Protein-tyrosine-phosphatase

Overview
NameProtein-tyrosine-phosphatase
Smed IDSMED30029055
Length (bp)1016
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Protein-tyrosine-phosphatase (SMED30029055) t-SNE clustered cells

Violin plots show distribution of expression levels for Protein-tyrosine-phosphatase (SMED30029055) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Protein-tyrosine-phosphatase (SMED30029055) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Protein-tyrosine-phosphatase (SMED30029055) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30029055

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 7

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
pigment cellSMED30029055 SmedASXL_019155SmedAsxl_ww_GCZZ01PMID:29158443
He et al., 2017		whole organism asexual adult RNA-sequencing evidence
Smed sexual biotypeSMED30029055 Contig50987newmark_estsPMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30029055 Contig50987uc_Smed_v2PMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
cephalic gangliaSMED30029055 dd_Smed_v4_4629_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymal cellSMED30029055 dd_Smed_v4_4629_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
tail regionSMED30029055 dd_Smed_v6_4629_0_1dd_Smed_v6PMID:28171748
Stückemann et al., 2017		whole organism asexual adult RNA-sequencing evidence
Category 3 cellSMED30029055 dd_Smed_v4_4629_0_1dd_Smed_v4PMID:28292427
Wurtzel et al., 2017		whole organism asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
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BLAST of Protein-tyrosine-phosphatase vs. TrEMBL
Match: A0A177QAL3 (TYR_PHOSPHATASE_2 domain-containing protein OS=bacterium SCGC AG-212-C10 OX=1799370 GN=AYO38_00120 PE=4 SV=1)

HSP 1 Score: 81.2629 bits (199), Expect = 5.838e-14
Identity = 53/180 (29.44%), Postives = 84/180 (46.67%), Query Frame = 2 
Query:  185 NFRPIIPSDRFHCSSM----IYRSNSIDDGKLDSVQWLFNEVKIKLILDLRNEIEFHPNSQLDQCYQLI----DFDEINEFQQNLDKYDSIKGYRCHVGFSYGNFNSQFGTVEDFYLHLIDNNKHVMKSIFSFMGNSKNFPILITCSYGKDRTGVVSAMVLDLVGCDQSTIIDEYLKSDA 700
            NFR + P       ++    IYRS +++        WL N++ I+ ++DLR+  EF    +  Q  +L+     F E    Q  + + + +          YGN     G   + YLH +    H     F  +  ++ +P+LI C+ GKDRTGVV  M++D++G     I DEY  SDA
Sbjct:   12 NFRAVAPYPLRGGGTIRANSIYRSGALELMTEADYAWLANDIGIRRVMDLRHPDEFGEGVK-HQLAELVCPLSIFPETGTQQSIIAELNGL----------YGN-----GPSPERYLHYLQAGSHRFVESFQVLAEAETYPVLIHCTAGKDRTGVVVGMLMDILGASDEDIADEYGLSDA 175
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BLAST of Protein-tyrosine-phosphatase vs. TrEMBL
Match: A0A417C6L4 (Protein-tyrosine-phosphatase OS=Erysipelatoclostridium sp. AM42-17 OX=2293102 GN=DW911_10430 PE=4 SV=1)

HSP 1 Score: 80.8777 bits (198), Expect = 5.935e-14
Identity = 69/200 (34.50%), Postives = 106/200 (53.00%), Query Frame = 2 
Query:  302 IKLILDLRNEIEFHPNSQLDQCYQLIDFDEINEFQ-QNLDK-YDSIKGYRCHVGFSYGNFNSQFGTVEDFYLHLIDNNKHVMKSIFSFMGNSKNFPILITCSYGKDRTGVVSAMVLDLVGCDQSTIIDEYLKSDALLKPVQERLNQIVKEKNINTEFAKCPIGAIKQFVIXXXXXXXXXXXXXXECGLTELDIEKIRSNL 895
            I+ ++DLR+  E        + YQ I++  I+  Q QN     D+IK Y+   GF               Y+ +I+ NK+ MK IF          I+  CS GKDRTGVVSA++LDL GC +  I+ +Y +S    KP+ ++L  ++KE+  + +F       + +F+ YL+  YG  K YL +CGL E  I++I+ NL
Sbjct:   60 IRTVVDLRSPFEVEQLPHPLKEYQDIEYYHIDLLQSQNFSLIADNIKEYQDLSGF---------------YIFMIEANKNQMKKIFEIFYEHPYDAIMFNCSAGKDRTGVVSALLLDLAGCHEYDIVKDYSESFENNKPILDQLKGMIKEE--DEKFLGSDPRIMMKFLAYLRETYGSAKEYLLQCGLDEEQIQEIKENL 242
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BLAST of Protein-tyrosine-phosphatase vs. TrEMBL
Match: A0A415RI38 (Protein-tyrosine-phosphatase OS=Coprobacillus sp. AF33-1AC OX=2292032 GN=DWZ53_10495 PE=4 SV=1)

HSP 1 Score: 80.8777 bits (198), Expect = 5.935e-14
Identity = 69/200 (34.50%), Postives = 106/200 (53.00%), Query Frame = 2 
Query:  302 IKLILDLRNEIEFHPNSQLDQCYQLIDFDEINEFQ-QNLDK-YDSIKGYRCHVGFSYGNFNSQFGTVEDFYLHLIDNNKHVMKSIFSFMGNSKNFPILITCSYGKDRTGVVSAMVLDLVGCDQSTIIDEYLKSDALLKPVQERLNQIVKEKNINTEFAKCPIGAIKQFVIXXXXXXXXXXXXXXECGLTELDIEKIRSNL 895
            I+ ++DLR+  E        + YQ I++  I+  Q QN     D+IK Y+   GF               Y+ +I+ NK+ MK IF          I+  CS GKDRTGVVSA++LDL GC +  I+ +Y +S    KP+ ++L  ++KE+  + +F       + +F+ YL+  YG  K YL +CGL E  I++I+ NL
Sbjct:   60 IRTVVDLRSPFEVEQLPHPLKEYQDIEYYHIDLLQSQNFSLIADNIKEYQDLSGF---------------YIFMIEANKNQMKKIFEIFYEHPYDAIMFNCSAGKDRTGVVSALLLDLAGCHEYDIVKDYSESFENNKPILDQLKGMIKEE--DEKFLGSDPRIMMKFLAYLRETYGSAKEYLLQCGLDEEQIQEIKENL 242
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BLAST of Protein-tyrosine-phosphatase vs. TrEMBL
Match: A0A507FTF4 (TYR_PHOSPHATASE_2 domain-containing protein OS=Chytriomyces confervae OX=246404 GN=CcCBS67573_g00324 PE=4 SV=1)

HSP 1 Score: 80.1073 bits (196), Expect = 1.689e-13
Identity = 55/147 (37.41%), Postives = 90/147 (61.22%), Query Frame = 2 
Query:  467 GNFNSQFGTVEDFYLHLIDNNKHVMKSIFSFMGNSKNFPILITCSYGKDRTGVVSAMVLDLVGCDQSTIIDEYLKSDALLKPVQERLNQIVKEKNINT-EFAKCPIGAIKQFVIXXXXXXXXXXXXXXECGLTELDIEKIRSNLLNV 904
            G+F ++ G +  FY+ L+DN+      IF F+    +FP+LI CS GKDRTG++SA++  L+G   + I+ +YL S+  L+ VQ  L + V +  +   EFA C   A+  F+ +L T+YGG   YL+  G++  + + +R+NLL+V
Sbjct:  115 GSFLNKPGGLTRFYIVLLDNHGDEFNRIFRFLTEKSHFPVLIHCSAGKDRTGILSALIHRLMGTPDADILKDYLLSNKGLESVQTLLEKEVDKMGMCVNEFAGCKEEAMIGFLDHLDTRYGGVHSYLESIGVSRAEQDLVRTNLLDV 261
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BLAST of Protein-tyrosine-phosphatase vs. TrEMBL
Match: V9L682 (TYR_PHOSPHATASE_2 domain-containing protein OS=Callorhinchus milii OX=7868 GN=LOC103182731 PE=2 SV=1)

HSP 1 Score: 76.6406 bits (187), Expect = 3.918e-12
Identity = 64/242 (26.45%), Postives = 103/242 (42.56%), Query Frame = 2 
Query:  167 MNLPPCNFRPIIPSDRFHCSSM--IYRSNSIDDGKLDSVQWLFNEVKIKLILDLRNEIEFHPNSQ-----LDQCYQLIDFDEINEFQQNLDKYDSIK-------GYRCHVGFSYGNFNSQFGT--------------------------------------VEDFYLHLIDNNKHVMKSIFSFMGNSKNFPILITCSYGKDRTGVVSAMVLDLVGCDQSTIIDEYLKSDALLKPVQERLNQI 736
            M + P N    IP+ R  CS    IYRS S D    + V+ L   + I+LI+DLR+  E   +S      +D  Y+ +   E  E +    K  + K       G RC + F+   + ++  T                                      V+  Y  L+D ++ V+ +I   +   +N P LI C+ GKDRTGV +A++   VG  +  II++Y  S   +KP+ E+L+ +
Sbjct:   11 MAIQPQN----IPNLRQLCSGFANIYRSASPDHASEEEVRVLKELLGIRLIIDLRSSEELQDSSHGGRKPIDISYERLKVTE-EEMEDTKRKGTTGKLLSGEAQGVRCVLSFATKKYKARLLTTMSACQKVLLMFMALIDRVFHTWLSQRYLTTRVLNPRGVKQQYTDLVDTSQTVIFTILKLLSEPRNVPALIHCTAGKDRTGVTAALIQLAVGWPKKNIIEDYTASTQGIKPIYEKLHTL 247
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BLAST of Protein-tyrosine-phosphatase vs. Planmine SMEST
Match: SMESG000055801.1 (SMESG000055801.1)

HSP 1 Score: 481.1 bits (1237), Expect = 3.455e-173
Identity = 250/252 (99.21%), Postives = 251/252 (99.60%), Query Frame = 2 
Query:  167 MNLPPCNFRPIIPSDRFHCSSMIYRSNSIDDGKLDSVQWLFNEVKIKLILDLRNEIEFHPNSQLDQCYQLIDFDEINEFQQNLDKYDSIKGYRCHVGFSYGNFNSQFGTVEDFYLHLIDNNKHVMKSIFSFMGNSKNFPILITCSYGKDRTGVVSAMVLDLVGCDQSTIIDEYLKSDALLKPVQERLNQIVKEKNINTEFAKCPIGAIKQFVIXXXXXXXXXXXXXXECGLTELDIEKIRSNLLNVTETNRD 922
            MNLPPCNFRPIIPSDRFHCSSMIYRSNSIDDGKLDSVQWLFNEVKIKLILDLRNEIEFHPNSQLDQCYQLIDFDEINEFQQNLDKYDSIKGYRCHVGFSYGNFNSQFGTVEDFYLHLIDNNKHVMKSIFSFMGNSKNFPILITCSYGKDRTGVVSAMVLDLVGCDQSTIIDEYLKSDALLKPVQERLNQIVKEKNIN EFAKCPIGAI+QFVIYLKTKYGGTKGYLKECGLTELDIEKIRSNLLNVTETNRD
Sbjct:    1 MNLPPCNFRPIIPSDRFHCSSMIYRSNSIDDGKLDSVQWLFNEVKIKLILDLRNEIEFHPNSQLDQCYQLIDFDEINEFQQNLDKYDSIKGYRCHVGFSYGNFNSQFGTVEDFYLHLIDNNKHVMKSIFSFMGNSKNFPILITCSYGKDRTGVVSAMVLDLVGCDQSTIIDEYLKSDALLKPVQERLNQIVKEKNINPEFAKCPIGAIQQFVIYLKTKYGGTKGYLKECGLTELDIEKIRSNLLNVTETNRD 252
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BLAST of Protein-tyrosine-phosphatase vs. Planmine SMEST
Match: SMESG000030078.1 (SMESG000030078.1)

HSP 1 Score: 139.043 bits (349), Expect = 1.131e-38
Identity = 93/283 (32.86%), Postives = 140/283 (49.47%), Query Frame = 2 
Query:  167 MNLPPCNFRPIIPSDRFHCSSMIYRSNSIDDGKLDSVQWLFNEVKIKLILDLRNEIEFHPNSQLDQCYQLIDFDEINEFQQNLDKYDSIKGYRCHVGF-----------------------------------SYGNFNSQ----FGTVEDFYLHLIDNNKHVMKSIFSFMGNSKNFPILITCSYGKDRTGVVSAMVLDLVGCDQSTIIDEYLKSDALLKPVQERLNQIVKEKNINTEFAKCPIGAIKQFVIXXXXXXXXXXXXXXECGLTELDIEKIRSNLL 898
            M LPPCNFRP+    R    + +YRSN+IDDG + S +WL   + I   +DLR   EFHP S+L       D+    +  + +       G R H+GF                                   +Y  +  Q      ++ +FY  L+D+ + V K IF+ M +  NFP++I CS+GKDRTG+V A++L LVG D   II EY KS+  L  +++ +    + K    E+   P  A+   + +LK KYG  + YLK CG+ E  IE+I++N++
Sbjct:    1 MELPPCNFRPVFSIHRASAGTNLYRSNAIDDGTVKSAKWLRETIGINSYVDLREGNEFHPMSKLG------DYFIQTKLNKPIKNPPGNFGRRYHMGFITVSYHWNLLIHKLKFNQIFVLIFLLIQHLIYRDYAYQKYGGQCYLSTLSLGEFYASLLDDCQKVFKQIFTTMTDPDNFPMIICCSFGKDRTGIVVALLLKLVGWDDEDIIKEYTKSEGNLDSLKDEIRSFFEFKGAGEEYCHAPRSAMVTMLAHLKEKYGTVENYLKSCGINEGQIEQIKTNIM 277
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BLAST of Protein-tyrosine-phosphatase vs. Planmine SMEST
Match: SMESG000055800.1 (SMESG000055800.1)

HSP 1 Score: 92.4337 bits (228), Expect = 5.764e-23
Identity = 57/114 (50.00%), Postives = 80/114 (70.18%), Query Frame = 2 
Query:  560 MGNSKNFPILITCSYGKDRTGVVSAMVLDLVGCDQSTIIDEYLKSDALLKPVQERLNQIVKEKNINTEFAKCPIGAIKQFVIXXXXXXXXXXXXXXECGLTELDIEKIRSNLLN 901
            M +  NFP++I C+YGKDRTGVV+A+ ++L GC    II EY +S  LLKP+QE+LN  +    I  EF +    A++ F+ YLK KYGG++GYLK CG+T   IEKI++N++N
Sbjct:    1 MADESNFPMIIACNYGKDRTGVVAAIAMELTGCSDQLIISEYSQSQNLLKPMQEKLNSEMNFYQIRQEFIQSSPKAMEMFLHYLKNKYGGSEGYLKFCGVTNEQIEKIKNNIMN 114
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BLAST of Protein-tyrosine-phosphatase vs. Planmine SMEST
Match: SMESG000055800.1 (SMESG000055800.1)

HSP 1 Score: 82.4185 bits (202), Expect = 2.627e-19
Identity = 53/106 (50.00%), Postives = 75/106 (70.75%), Query Frame = 2 
Query:  584 ILITCSYGKDRTGVVSAMVLDLVGCDQSTIIDEYLKSDALLKPVQERLNQIVKEKNINTEFAKCPIGAIKQFVIXXXXXXXXXXXXXXECGLTELDIEKIRSNLLN 901
            ++I C+YGKDRTGVV+A+ ++L GC    II EY +S  LLKP+QE+LN  +    I  EF +    A++ F+ YLK KYGG++GYLK CG+T   IEKI++N++N
Sbjct:    1 MIIACNYGKDRTGVVAAIAMELTGCSDQLIISEYSQSQNLLKPMQEKLNSEMNFYQIRQEFIQSSPKAMEMFLHYLKNKYGGSEGYLKFCGVTNEQIEKIKNNIMN 106
The following BLAST results are available for this feature:
BLAST of Protein-tyrosine-phosphatase vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Protein-tyrosine-phosphatase vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Protein-tyrosine-phosphatase vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Protein-tyrosine-phosphatase vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Protein-tyrosine-phosphatase vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Protein-tyrosine-phosphatase vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Protein-tyrosine-phosphatase vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Protein-tyrosine-phosphatase vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A177QAL35.838e-1429.44TYR_PHOSPHATASE_2 domain-containing protein OS=bac... [more]
A0A417C6L45.935e-1434.50Protein-tyrosine-phosphatase OS=Erysipelatoclostri... [more]
A0A415RI385.935e-1434.50Protein-tyrosine-phosphatase OS=Coprobacillus sp. ... [more]
A0A507FTF41.689e-1337.41TYR_PHOSPHATASE_2 domain-containing protein OS=Chy... [more]
V9L6823.918e-1226.45TYR_PHOSPHATASE_2 domain-containing protein OS=Cal... [more]
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BLAST of Protein-tyrosine-phosphatase vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Protein-tyrosine-phosphatase vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Protein-tyrosine-phosphatase vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Protein-tyrosine-phosphatase vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Protein-tyrosine-phosphatase vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Protein-tyrosine-phosphatase vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 4
Match NameE-valueIdentityDescription
SMESG000055801.13.455e-17399.21SMESG000055801.1[more]
SMESG000030078.11.131e-3832.86SMESG000030078.1[more]
SMESG000055800.15.764e-2350.00SMESG000055800.1[more]
SMESG000055800.12.627e-1950.00SMESG000055800.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30029055 ID=SMED30029055|Name=Protein-tyrosine-phosphatase|organism=Schmidtea mediterranea sexual|type=transcript|length=1016bp
TCTAATTTATTTAGTAAAAACGAAATTGATTTCATTGTAGAAAACGACAA
AAACAACAACAAAATTGAAACATTTAAAGTGCAAATCATTTAGCATTGAA
CACAGAATTTGCAGACAATTTATAGAAATCATCAACAGATAATTATTGAT
TACTATTGTCATATCGATGAATCTGCCGCCTTGCAATTTTAGACCAATCA
TTCCATCGGATCGATTTCATTGCTCGTCGATGATTTACAGATCGAACTCA
ATCGATGACGGCAAATTGGATTCTGTCCAATGGCTTTTCAATGAAGTTAA
AATCAAATTGATTTTAGATCTTAGAAATGAAATTGAGTTTCATCCGAATA
GCCAATTAGATCAATGCTATCAATTGATTGATTTCGATGAAATCAACGAA
TTCCAGCAAAACCTCGATAAATATGACTCGATCAAAGGCTACAGATGTCA
TGTGGGATTTTCTTATGGAAATTTCAATTCGCAATTCGGAACTGTTGAGG
ATTTTTATTTACATTTAATTGACAACAACAAACATGTGATGAAGTCAATT
TTTTCTTTCATGGGCAATTCGAAGAATTTTCCCATTTTAATTACTTGCAG
TTATGGAAAGGATCGAACTGGGGTCGTTTCCGCCATGGTTTTGGATTTGG
TTGGTTGTGATCAATCGACAATCATTGATGAATATTTAAAATCGGATGCT
CTGTTAAAACCTGTCCAAGAAAGGCTAAATCAAATTGTGAAGGAAAAGAA
TATAAATACAGAATTTGCAAAGTGTCCGATCGGTGCTATCAAGCAATTTG
TTATTTATTTAAAAACAAAATACGGAGGTACTAAAGGATATCTGAAAGAA
TGTGGACTTACGGAACTGGATATTGAGAAAATTAGATCCAATCTCTTGAA
TGTTACTGAAACCAATCGTGATTAAAATTTTATATTTTAATAATACCATT
TCAGTGATTTAAATATAAATTTATCAAATGATATTTTTAATAGAAATACT
ATCAGCCCAATCTTTT
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protein sequence of SMED30029055-orf-1

>SMED30029055-orf-1 ID=SMED30029055-orf-1|Name=SMED30029055-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=253bp
MNLPPCNFRPIIPSDRFHCSSMIYRSNSIDDGKLDSVQWLFNEVKIKLIL
DLRNEIEFHPNSQLDQCYQLIDFDEINEFQQNLDKYDSIKGYRCHVGFSY
GNFNSQFGTVEDFYLHLIDNNKHVMKSIFSFMGNSKNFPILITCSYGKDR
TGVVSAMVLDLVGCDQSTIIDEYLKSDALLKPVQERLNQIVKEKNINTEF
AKCPIGAIKQFVIYLKTKYGGTKGYLKECGLTELDIEKIRSNLLNVTETN
RD*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000035Category 3 cell
PLANA:0000421tail
PLANA:0002075pigment cell
PLANA:0003116parenchymal cell
Vocabulary: INTERPRO
TermDefinition
IPR029021Prot-tyrosine_phosphatase-like
IPR026893Tyr/Ser_Pase_IphP-type
Vocabulary: molecular function
TermDefinition
GO:0004725protein tyrosine phosphatase activity
GO:0016791phosphatase activity
Vocabulary: biological process
TermDefinition
GO:0016311dephosphorylation
GO:0035335peptidyl-tyrosine dephosphorylation
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR026893Tyrosine/serine-protein phosphatase IphP-typePFAMPF13350Y_phosphatase3coord: 21..244
e-value: 6.9E-35
score: 121.1
IPR029021Protein-tyrosine phosphatase-likeGENE3DG3DSA:3.90.190.10coord: 6..245
e-value: 8.4E-38
score: 132.6
IPR029021Protein-tyrosine phosphatase-likeSUPERFAMILYSSF52799(Phosphotyrosine protein) phosphatases IIcoord: 7..244
NoneNo IPR availablePANTHERPTHR31126FAMILY NOT NAMEDcoord: 7..244
NoneNo IPR availablePANTHERPTHR31126:SF1PTP/DSP-LIKEcoord: 7..244
NoneNo IPR availableCDDcd14529TpbA-likecoord: 6..174
e-value: 2.24824E-12
score: 61.2358