Elongin B
Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30029051 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 18
Homology
BLAST of Elongin B vs. Ensembl Human
Match: ELOB (elongin B [Source:HGNC Symbol;Acc:HGNC:11619]) HSP 1 Score: 117.087 bits (292), Expect = 6.279e-34 Identity = 56/111 (50.45%), Postives = 76/111 (68.47%), Query Frame = 1 Query: 43 MDVYLMVKRKKTSIFLDCKENSTVMEIKKMIEGILKVQPENQMLYKDKTVMEDTKTVAEYNLNSLTSRAQTPSLLGLCLRDLEIGNFETLEIFPLSVPPELPEVMRTQDQS 375 MDV+LM++R KT+IF D KE+STV E+K+++EGILK P+ Q LYKD +++D KT+ E S T+R Q P+ +GL R + FE L I P S PPELP+VM+ QD Sbjct: 1 MDVFLMIRRHKTTIFTDAKESSTVFELKRIVEGILKRPPDEQRLYKDDQLLDDGKTLGECGFTSQTARPQAPATVGLAFRADD--TFEALCIEPFSSPPELPDVMKPQDSG 109
BLAST of Elongin B vs. Ensembl Human
Match: ELOB (elongin B [Source:HGNC Symbol;Acc:HGNC:11619]) HSP 1 Score: 117.857 bits (294), Expect = 1.209e-33 Identity = 56/109 (51.38%), Postives = 76/109 (69.72%), Query Frame = 1 Query: 43 MDVYLMVKRKKTSIFLDCKENSTVMEIKKMIEGILKVQPENQMLYKDKTVMEDTKTVAEYNLNSLTSRAQTPSLLGLCLRDLEIGNFETLEIFPLSVPPELPEVMRTQD 369 MDV+LM++R KT+IF D KE+STV E+K+++EGILK P+ Q LYKD +++D KT+ E S T+R Q P+ +GL R + FE L I P S PPELP+VM+ QD Sbjct: 1 MDVFLMIRRHKTTIFTDAKESSTVFELKRIVEGILKRPPDEQRLYKDDQLLDDGKTLGECGFTSQTARPQAPATVGLAFRADD--TFEALCIEPFSSPPELPDVMKPQD 107
BLAST of Elongin B vs. Ensembl Human
Match: ELOB (elongin B [Source:HGNC Symbol;Acc:HGNC:11619]) HSP 1 Score: 108.227 bits (269), Expect = 1.964e-30 Identity = 52/104 (50.00%), Postives = 71/104 (68.27%), Query Frame = 1 Query: 58 MVKRKKTSIFLDCKENSTVMEIKKMIEGILKVQPENQMLYKDKTVMEDTKTVAEYNLNSLTSRAQTPSLLGLCLRDLEIGNFETLEIFPLSVPPELPEVMRTQD 369 M++R KT+IF D KE+STV E+K+++EGILK P+ Q LYKD +++D KT+ E S T+R Q P+ +GL R + FE L I P S PPELP+VM+ QD Sbjct: 1 MIRRHKTTIFTDAKESSTVFELKRIVEGILKRPPDEQRLYKDDQLLDDGKTLGECGFTSQTARPQAPATVGLAFRADD--TFEALCIEPFSSPPELPDVMKPQD 102
BLAST of Elongin B vs. Ensembl Human
Match: ELOB (elongin B [Source:HGNC Symbol;Acc:HGNC:11619]) HSP 1 Score: 101.679 bits (252), Expect = 1.243e-27 Identity = 55/133 (41.35%), Postives = 75/133 (56.39%), Query Frame = 1 Query: 46 DVYLMVKRKKTSIFLDCKENSTVMEIKKMIEGILKVQPENQMLYK-----------------------DKTVMEDTKTVAEYNLNSLTSRAQTPSLLGLCLRDLEIGNFETLEIFPLSVPPELPEVMRTQDQS 375 DV+LM++R KT+IF D KE+STV E+K+++EGILK P+ Q LYK D +++D KT+ E S T+R Q P+ +GL R + FE L I P S PPELP+VM+ QD Sbjct: 1 DVFLMIRRHKTTIFTDAKESSTVFELKRIVEGILKRPPDEQRLYKLLVRSLWDLPHVGPLPRSCFSPQDDQLLDDGKTLGECGFTSQTARPQAPATVGLAFRADD--TFEALCIEPFSSPPELPDVMKPQDSG 131
BLAST of Elongin B vs. Ensembl Human
Match: ELOB (elongin B [Source:HGNC Symbol;Acc:HGNC:11619]) HSP 1 Score: 64.6994 bits (156), Expect = 4.036e-14 Identity = 28/46 (60.87%), Postives = 38/46 (82.61%), Query Frame = 1 Query: 43 MDVYLMVKRKKTSIFLDCKENSTVMEIKKMIEGILKVQPENQMLYK 180 MDV+LM++R KT+IF D KE+STV E+K+++EGILK P+ Q LYK Sbjct: 1 MDVFLMIRRHKTTIFTDAKESSTVFELKRIVEGILKRPPDEQRLYK 46
BLAST of Elongin B vs. Ensembl Celegans
Match: elb-1 (ELongin B; RNA polymerase II transcription factor SIII p18 subunit [Source:UniProtKB/TrEMBL;Acc:G5ECR7]) HSP 1 Score: 68.1662 bits (165), Expect = 2.487e-15 Identity = 41/118 (34.75%), Postives = 70/118 (59.32%), Query Frame = 1 Query: 46 DVYLMVKRKKTSIFLDCKENSTVMEIKKMIEGILKVQPENQM-LYK------DKTVMEDTKTVAEYNLNSLTSRAQTPSLLGLCLRDLEIGNFETLEIFPLSVPPELPEVMRTQDQSP 378 +++ V+R ++ I+LD +E+ +VME+K M+ GI + P N M L+K ++ DT T+++ +S ++AQ P+ LGL L + E E L I +S P +P+ MR Q+Q+P Sbjct: 5 ELFFEVRRNRSHIYLDAEESHSVMELKLMLAGITR-DPVNHMELWKLDEDGNKSQLLHDTATLSDAGFSSTNAKAQCPAALGLRLTNAE----EHLTISDVSTAPPIPDTMR-QEQAP 116
BLAST of Elongin B vs. Ensembl Fly
Match: EloB (gene:FBgn0023212 transcript:FBtr0083947) HSP 1 Score: 133.265 bits (334), Expect = 1.119e-40 Identity = 64/115 (55.65%), Postives = 88/115 (76.52%), Query Frame = 1 Query: 43 MDVYLMVKRKKTSIFLDCKENSTVMEIKKMIEGILKVQPENQMLY-KDKTVMEDTKTVAEYNLNSLTSRAQTPSLLGLCLRDLEIGNFETLEIFPLSVPPELPEVMRTQDQSPLQ 384 MDV+LM++R+KT+IF D KEN+TV E+K+MIEGILKVQP +Q LY +D VMED T+ +Y + T++AQ P+ LGL R+ E+G+FETL++ P S PP+LPEVM+ Q+ S Q Sbjct: 1 MDVFLMIRRQKTTIFTDAKENTTVAELKRMIEGILKVQPVDQRLYNQDNDVMEDDSTLQDYGVTVSTAKAQAPAQLGLTFRN-EVGDFETLDMTPYSAPPDLPEVMKNQEASNGQ 114
BLAST of Elongin B vs. Ensembl Zebrafish
Match: elob (elongin B [Source:ZFIN;Acc:ZDB-GENE-020415-1]) HSP 1 Score: 115.546 bits (288), Expect = 1.973e-33 Identity = 54/111 (48.65%), Postives = 77/111 (69.37%), Query Frame = 1 Query: 43 MDVYLMVKRKKTSIFLDCKENSTVMEIKKMIEGILKVQPENQMLYKDKTVMEDTKTVAEYNLNSLTSRAQTPSLLGLCLRDLEIGNFETLEIFPLSVPPELPEVMRTQDQS 375 MDV+LM++R KT+IF D KE++TV E+K+++EGILK PE+Q LYKD ++ED+KT+ + + T+R Q P+ +GL R + FE L I S PPELP+VM+ QD Sbjct: 1 MDVFLMIRRHKTTIFTDAKESTTVYELKRIVEGILKRAPEDQRLYKDDMLLEDSKTLGDCGFTNQTARPQAPATVGLAFR-ISDDAFEPLRIEAFSSPPELPDVMKPQDSG 110
BLAST of Elongin B vs. Ensembl Zebrafish
Match: elob (elongin B [Source:ZFIN;Acc:ZDB-GENE-020415-1]) HSP 1 Score: 106.301 bits (264), Expect = 5.401e-30 Identity = 50/104 (48.08%), Postives = 72/104 (69.23%), Query Frame = 1 Query: 58 MVKRKKTSIFLDCKENSTVMEIKKMIEGILKVQPENQMLYKDKTVMEDTKTVAEYNLNSLTSRAQTPSLLGLCLRDLEIGNFETLEIFPLSVPPELPEVMRTQD 369 M++R KT+IF D KE++TV E+K+++EGILK PE+Q LYKD ++ED+KT+ + + T+R Q P+ +GL R + FE L I S PPELP+VM+ QD Sbjct: 1 MIRRHKTTIFTDAKESTTVYELKRIVEGILKRAPEDQRLYKDDMLLEDSKTLGDCGFTNQTARPQAPATVGLAFR-ISDDAFEPLRIEAFSSPPELPDVMKPQD 103
BLAST of Elongin B vs. Ensembl Zebrafish
Match: elob (elongin B [Source:ZFIN;Acc:ZDB-GENE-020415-1]) HSP 1 Score: 106.301 bits (264), Expect = 5.401e-30 Identity = 50/104 (48.08%), Postives = 72/104 (69.23%), Query Frame = 1 Query: 58 MVKRKKTSIFLDCKENSTVMEIKKMIEGILKVQPENQMLYKDKTVMEDTKTVAEYNLNSLTSRAQTPSLLGLCLRDLEIGNFETLEIFPLSVPPELPEVMRTQD 369 M++R KT+IF D KE++TV E+K+++EGILK PE+Q LYKD ++ED+KT+ + + T+R Q P+ +GL R + FE L I S PPELP+VM+ QD Sbjct: 1 MIRRHKTTIFTDAKESTTVYELKRIVEGILKRAPEDQRLYKDDMLLEDSKTLGDCGFTNQTARPQAPATVGLAFR-ISDDAFEPLRIEAFSSPPELPDVMKPQD 103
BLAST of Elongin B vs. Ensembl Zebrafish
Match: BX004999.2 (pep chromosome:GRCz11:3:31066787:31079186:-1 gene:ENSDARG00000097471.2 transcript:ENSDART00000145636.2 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:BX004999.2) HSP 1 Score: 67.3958 bits (163), Expect = 3.093e-15 Identity = 28/48 (58.33%), Postives = 41/48 (85.42%), Query Frame = 1 Query: 43 MDVYLMVKRKKTSIFLDCKENSTVMEIKKMIEGILKVQPENQMLYKDK 186 MDV+LM++R KT+IF D KE++TV E+K+++EGILK PE+Q LYK++ Sbjct: 8 MDVFLMIRRHKTTIFTDAKESTTVYELKRIVEGILKRAPEDQRLYKER 55
BLAST of Elongin B vs. Ensembl Xenopus
Match: fam210a (family with sequence similarity 210 member A [Source:Xenbase;Acc:XB-GENE-944382]) HSP 1 Score: 115.931 bits (289), Expect = 1.779e-33 Identity = 54/111 (48.65%), Postives = 77/111 (69.37%), Query Frame = 1 Query: 43 MDVYLMVKRKKTSIFLDCKENSTVMEIKKMIEGILKVQPENQMLYKDKTVMEDTKTVAEYNLNSLTSRAQTPSLLGLCLRDLEIGNFETLEIFPLSVPPELPEVMRTQDQS 375 MDV+LM++ KT+IF D KE++TV E+K+++EGILK PE+Q LYKD V++D KT+ + S T+R Q P+ +GL R +FE L + P S PPELP+VM+ Q+ S Sbjct: 1 MDVFLMIRHHKTTIFTDAKESTTVYELKRIVEGILKRPPEDQKLYKDDQVLDDNKTLGDCGFTSQTARPQAPATVGLAFRS-SGDSFEPLRVDPFSSPPELPDVMKPQETS 110
BLAST of Elongin B vs. Ensembl Mouse
Match: Elob (elongin B [Source:MGI Symbol;Acc:MGI:1914923]) HSP 1 Score: 120.553 bits (301), Expect = 2.180e-35 Identity = 57/111 (51.35%), Postives = 76/111 (68.47%), Query Frame = 1 Query: 43 MDVYLMVKRKKTSIFLDCKENSTVMEIKKMIEGILKVQPENQMLYKDKTVMEDTKTVAEYNLNSLTSRAQTPSLLGLCLRDLEIGNFETLEIFPLSVPPELPEVMRTQDQS 375 MDV+LM++R KT+IF D KE+STV E+K+++EGILK PE Q LYKD +++D KT+ E S T+R Q P+ +GL R + FE L I P S PPELP+VM+ QD Sbjct: 1 MDVFLMIRRHKTTIFTDAKESSTVFELKRIVEGILKRPPEEQRLYKDDQLLDDGKTLGECGFTSQTARPQAPATVGLAFRADD--TFEALRIEPFSSPPELPDVMKPQDSG 109
BLAST of Elongin B vs. Ensembl Mouse
Match: Elob (elongin B [Source:MGI Symbol;Acc:MGI:1914923]) HSP 1 Score: 95.5153 bits (236), Expect = 6.122e-26 Identity = 42/80 (52.50%), Postives = 58/80 (72.50%), Query Frame = 1 Query: 43 MDVYLMVKRKKTSIFLDCKENSTVMEIKKMIEGILKVQPENQMLYKDKTVMEDTKTVAEYNLNSLTSRAQTPSLLGLCLR 282 MDV+LM++R KT+IF D KE+STV E+K+++EGILK PE Q LYKD +++D KT+ E S T+R Q P+ +GL R Sbjct: 1 MDVFLMIRRHKTTIFTDAKESSTVFELKRIVEGILKRPPEEQRLYKDDQLLDDGKTLGECGFTSQTARPQAPATVGLAFR 80
BLAST of Elongin B vs. Ensembl Mouse
Match: Elobl (elongin B-like [Source:MGI Symbol;Acc:MGI:1860403]) HSP 1 Score: 91.6633 bits (226), Expect = 2.337e-24 Identity = 43/98 (43.88%), Postives = 67/98 (68.37%), Query Frame = 1 Query: 31 VAESMDVYLMVKRKKTSIFLDCKENSTVMEIKKMIEGILKVQPENQMLYKDKTVMEDTKTVAEYNLNSLTSRAQTPSLLGLCLRDLEIGNFETLEIFP 324 A+ MDV+LM++ KKT+I D KE+STV+ +K++IEGI+K PE Q+L+KD ++++ KT+ E S +R + P+ +GL R ++ FE LEI P Sbjct: 5 AAKGMDVFLMIRYKKTTILTDAKESSTVLALKRIIEGIMKRPPEEQLLFKDNQLLDEMKTLRECGFTSQVARPEAPATVGLAFRTGDV--FEGLEIHP 100
BLAST of Elongin B vs. Ensembl Mouse
Match: Elobl (elongin B-like [Source:MGI Symbol;Acc:MGI:1860403]) HSP 1 Score: 89.3521 bits (220), Expect = 8.439e-23 Identity = 43/96 (44.79%), Postives = 66/96 (68.75%), Query Frame = 1 Query: 43 MDVYLMVKRKKTSIFLDCKENSTVMEIKKMIEGILKVQPENQMLYKDKTVMEDTKTVAEYNLNSLTSRAQTPSLLGLCLRDLEIGNFETLEIFPLS 330 MDV+LM++ KKT+I D KE+STV+ +K++IEGI+K PE Q+L+KD ++++ KT+ E S +R + P+ +GL R ++ FE LEI P S Sbjct: 1 MDVFLMIRYKKTTILTDAKESSTVLALKRIIEGIMKRPPEEQLLFKDNQLLDEMKTLRECGFTSQVARPEAPATVGLAFRTGDV--FEGLEIHPYS 94
BLAST of Elongin B vs. Ensembl Mouse
Match: Elobl (elongin B-like [Source:MGI Symbol;Acc:MGI:1860403]) HSP 1 Score: 89.3521 bits (220), Expect = 8.439e-23 Identity = 43/96 (44.79%), Postives = 66/96 (68.75%), Query Frame = 1 Query: 43 MDVYLMVKRKKTSIFLDCKENSTVMEIKKMIEGILKVQPENQMLYKDKTVMEDTKTVAEYNLNSLTSRAQTPSLLGLCLRDLEIGNFETLEIFPLS 330 MDV+LM++ KKT+I D KE+STV+ +K++IEGI+K PE Q+L+KD ++++ KT+ E S +R + P+ +GL R ++ FE LEI P S Sbjct: 1 MDVFLMIRYKKTTILTDAKESSTVLALKRIIEGIMKRPPEEQLLFKDNQLLDEMKTLRECGFTSQVARPEAPATVGLAFRTGDV--FEGLEIHPYS 94
BLAST of Elongin B vs. UniProt/SwissProt
Match: sp|P62870|ELOB_RAT (Elongin-B OS=Rattus norvegicus OX=10116 GN=Elob PE=1 SV=1) HSP 1 Score: 120.553 bits (301), Expect = 1.525e-34 Identity = 57/111 (51.35%), Postives = 76/111 (68.47%), Query Frame = 1 Query: 43 MDVYLMVKRKKTSIFLDCKENSTVMEIKKMIEGILKVQPENQMLYKDKTVMEDTKTVAEYNLNSLTSRAQTPSLLGLCLRDLEIGNFETLEIFPLSVPPELPEVMRTQDQS 375 MDV+LM++R KT+IF D KE+STV E+K+++EGILK PE Q LYKD +++D KT+ E S T+R Q P+ +GL R + FE L I P S PPELP+VM+ QD Sbjct: 1 MDVFLMIRRHKTTIFTDAKESSTVFELKRIVEGILKRPPEEQRLYKDDQLLDDGKTLGECGFTSQTARPQAPATVGLAFRADD--TFEALRIEPFSSPPELPDVMKPQDSG 109
BLAST of Elongin B vs. UniProt/SwissProt
Match: sp|P62869|ELOB_MOUSE (Elongin-B OS=Mus musculus OX=10090 GN=Elob PE=1 SV=1) HSP 1 Score: 120.553 bits (301), Expect = 1.525e-34 Identity = 57/111 (51.35%), Postives = 76/111 (68.47%), Query Frame = 1 Query: 43 MDVYLMVKRKKTSIFLDCKENSTVMEIKKMIEGILKVQPENQMLYKDKTVMEDTKTVAEYNLNSLTSRAQTPSLLGLCLRDLEIGNFETLEIFPLSVPPELPEVMRTQDQS 375 MDV+LM++R KT+IF D KE+STV E+K+++EGILK PE Q LYKD +++D KT+ E S T+R Q P+ +GL R + FE L I P S PPELP+VM+ QD Sbjct: 1 MDVFLMIRRHKTTIFTDAKESSTVFELKRIVEGILKRPPEEQRLYKDDQLLDDGKTLGECGFTSQTARPQAPATVGLAFRADD--TFEALRIEPFSSPPELPDVMKPQDSG 109
BLAST of Elongin B vs. UniProt/SwissProt
Match: sp|Q15370|ELOB_HUMAN (Elongin-B OS=Homo sapiens OX=9606 GN=ELOB PE=1 SV=1) HSP 1 Score: 117.087 bits (292), Expect = 3.015e-33 Identity = 56/111 (50.45%), Postives = 76/111 (68.47%), Query Frame = 1 Query: 43 MDVYLMVKRKKTSIFLDCKENSTVMEIKKMIEGILKVQPENQMLYKDKTVMEDTKTVAEYNLNSLTSRAQTPSLLGLCLRDLEIGNFETLEIFPLSVPPELPEVMRTQDQS 375 MDV+LM++R KT+IF D KE+STV E+K+++EGILK P+ Q LYKD +++D KT+ E S T+R Q P+ +GL R + FE L I P S PPELP+VM+ QD Sbjct: 1 MDVFLMIRRHKTTIFTDAKESSTVFELKRIVEGILKRPPDEQRLYKDDQLLDDGKTLGECGFTSQTARPQAPATVGLAFRADD--TFEALCIEPFSSPPELPDVMKPQDSG 109
BLAST of Elongin B vs. TrEMBL
Match: C1L5E2 (Elongin B OS=Schistosoma japonicum OX=6182 GN=Elongin-B PE=2 SV=1) HSP 1 Score: 150.599 bits (379), Expect = 8.457e-44 Identity = 72/118 (61.02%), Postives = 93/118 (78.81%), Query Frame = 1 Query: 43 MDVYLMVKRKKTSIFLDCKENSTVMEIKKMIEGILKVQPENQMLYKDKTVMEDTKTVAEYNLNSLTSRAQTPSLLGLCLRDLEIGNFETLEIFPLSVPPELPEVMRTQDQSPLQTGSE 396 MDVY++V+RKKT+I L+ +E S V+E+KKMIEGI+KV+PE+QML K +T M+D KT++ YNLNS T+RA TP+ LGLCLRD FETL+I P S PPELPEVMR+Q+ P Q+ E Sbjct: 1 MDVYMVVRRKKTTIHLNARETSLVLEVKKMIEGIIKVKPEDQMLLKHQTEMDDEKTLSYYNLNSQTARAHTPATLGLCLRDPTTEKFETLDITPYSNPPELPEVMRSQENLPPQSAPE 118
BLAST of Elongin B vs. TrEMBL
Match: A0A5K4EHA3 (Putative elongin B OS=Schistosoma mansoni OX=6183 PE=4 SV=1) HSP 1 Score: 149.058 bits (375), Expect = 2.907e-43 Identity = 72/118 (61.02%), Postives = 92/118 (77.97%), Query Frame = 1 Query: 43 MDVYLMVKRKKTSIFLDCKENSTVMEIKKMIEGILKVQPENQMLYKDKTVMEDTKTVAEYNLNSLTSRAQTPSLLGLCLRDLEIGNFETLEIFPLSVPPELPEVMRTQDQSPLQTGSE 396 M+VY++V+RKKT+I L KE S V+E+KKMIEGILKV+PE+QML K +T M+D K+++ YNLNS T+RA TP+ LGLCLRD FETL+I P S PPELPEVMR+Q+ P Q+ E Sbjct: 1 MEVYMVVRRKKTTIHLSAKETSLVLEVKKMIEGILKVKPEDQMLLKHQTEMDDEKSLSYYNLNSQTARAHTPATLGLCLRDPATEKFETLDITPYSNPPELPEVMRSQENLPPQSAPE 118
BLAST of Elongin B vs. TrEMBL
Match: B7PDP5 (RNA polymerase II transcription elongation factor, putative OS=Ixodes scapularis OX=6945 GN=8028374 PE=4 SV=1) HSP 1 Score: 144.436 bits (363), Expect = 1.379e-41 Identity = 65/106 (61.32%), Postives = 84/106 (79.25%), Query Frame = 1 Query: 43 MDVYLMVKRKKTSIFLDCKENSTVMEIKKMIEGILKVQPENQMLYKDKTVMEDTKTVAEYNLNSLTSRAQTPSLLGLCLRDLEIGNFETLEIFPLSVPPELPEVMR 360 MDV+LMV+RKKT++FLD KE ++V E+KKMI GI KV PENQMLYKD+ M+D K + EY LNS T++AQ P+ +GL RDL+ G FE L++ PLS PPELP+VM+ Sbjct: 1 MDVFLMVRRKKTTVFLDAKETTSVRELKKMIAGITKVAPENQMLYKDEQCMDDNKMLTEYGLNSSTAKAQAPATVGLAFRDLDSGKFENLDVTPLSSPPELPDVMK 106
BLAST of Elongin B vs. TrEMBL
Match: A0A131ZA95 (Transcription elongation factor B, polypeptide 2 (Fragment) OS=Rhipicephalus appendiculatus OX=34631 PE=4 SV=1) HSP 1 Score: 145.591 bits (366), Expect = 2.369e-41 Identity = 66/109 (60.55%), Postives = 85/109 (77.98%), Query Frame = 1 Query: 34 AESMDVYLMVKRKKTSIFLDCKENSTVMEIKKMIEGILKVQPENQMLYKDKTVMEDTKTVAEYNLNSLTSRAQTPSLLGLCLRDLEIGNFETLEIFPLSVPPELPEVMR 360 A++MDV+LMV+RKKT+IFLD KE ++V E+KKMI GI KV PENQ+LYKD M+D K + EY LNS T++AQ P+ +GL RD + G FE LE+ PLS PPELP+VM+ Sbjct: 45 ADTMDVFLMVRRKKTTIFLDAKETTSVRELKKMIAGITKVAPENQVLYKDDQCMDDNKVLTEYGLNSSTAKAQAPATVGLAFRDPDTGKFEPLEVTPLSSPPELPDVMK 153
BLAST of Elongin B vs. TrEMBL
Match: A0A504YIH8 (Putative rna polymerase ii transcription elongation factor elongin/siii subunit elongin b OS=Fasciola gigantica OX=46835 GN=FGIG_06007 PE=4 SV=1) HSP 1 Score: 144.05 bits (362), Expect = 2.985e-41 Identity = 70/112 (62.50%), Postives = 85/112 (75.89%), Query Frame = 1 Query: 43 MDVYLMVKRKKTSIFLDCKENSTVMEIKKMIEGILKVQPENQMLYKDKTVMEDTKTVAEYNLNSLTSRAQTPSLLGLCLRDLEIGNFETLEIFPLSVPPELPEVMRTQDQSP 378 M+VY++V+RKKT+I L+ KE +TV+E+KKMIEGILKV PENQM+ K T +ED KT+ YNLN T+RA TP+ LGLCLRD FE L+I P SVPPELPEVMR D P Sbjct: 1 MEVYMVVRRKKTTIHLNAKETTTVLEVKKMIEGILKVPPENQMILKHLTELEDDKTLGYYNLNGQTARAHTPASLGLCLRDPATEKFEALDITPYSVPPELPEVMRCPDNMP 112
BLAST of Elongin B vs. Ensembl Cavefish
Match: ENSAMXT00000037441.1 (elongin B [Source:NCBI gene;Acc:103031344]) HSP 1 Score: 115.546 bits (288), Expect = 1.483e-33 Identity = 52/109 (47.71%), Postives = 80/109 (73.39%), Query Frame = 1 Query: 43 MDVYLMVKRKKTSIFLDCKENSTVMEIKKMIEGILKVQPENQMLYKDKTVMEDTKTVAEYNLNSLTSRAQTPSLLGLCLRDLEIGNFETLEIFPLSVPPELPEVMRTQD 369 MDV+LM++R KT+IF D KE++TV E+K++++GILK PE+Q LYKD+ ++ED+KT+ + + T+R Q+P+ +GL R + FE L++ S PPELP+VM+ QD Sbjct: 1 MDVFLMIRRHKTTIFTDAKESTTVYELKRIVQGILKRPPEDQRLYKDEQLLEDSKTLGDSGFTNQTARPQSPATVGLAFR-INDDTFEPLQVEAFSNPPELPDVMKPQD 108
BLAST of Elongin B vs. Ensembl Cavefish
Match: elob (elongin B [Source:ZFIN;Acc:ZDB-GENE-020415-1]) HSP 1 Score: 107.071 bits (266), Expect = 2.209e-30 Identity = 50/104 (48.08%), Postives = 72/104 (69.23%), Query Frame = 1 Query: 58 MVKRKKTSIFLDCKENSTVMEIKKMIEGILKVQPENQMLYKDKTVMEDTKTVAEYNLNSLTSRAQTPSLLGLCLRDLEIGNFETLEIFPLSVPPELPEVMRTQD 369 M++R KT+IF D KE++TV E+K+++EGILK PE Q LYKD ++ED+KT+ + + T+R Q P+ +GL R + FE L + P S PPELP+VM+ QD Sbjct: 1 MIRRHKTTIFTDAKESTTVYELKRIVEGILKRPPEEQRLYKDDMLLEDSKTLGDCGFTNQTARPQAPATVGLAFR-VSDDAFEPLRVEPFSSPPELPDVMKPQD 103
BLAST of Elongin B vs. Ensembl Cavefish
Match: ELOB (elongin B [Source:HGNC Symbol;Acc:HGNC:11619]) HSP 1 Score: 107.071 bits (266), Expect = 2.209e-30 Identity = 50/104 (48.08%), Postives = 72/104 (69.23%), Query Frame = 1 Query: 58 MVKRKKTSIFLDCKENSTVMEIKKMIEGILKVQPENQMLYKDKTVMEDTKTVAEYNLNSLTSRAQTPSLLGLCLRDLEIGNFETLEIFPLSVPPELPEVMRTQD 369 M++R KT+IF D KE++TV E+K+++EGILK PE Q LYKD ++ED+KT+ + + T+R Q P+ +GL R + FE L + P S PPELP+VM+ QD Sbjct: 1 MIRRHKTTIFTDAKESTTVYELKRIVEGILKRPPEEQRLYKDDMLLEDSKTLGDCGFTNQTARPQAPATVGLAFR-VSDDAFEPLRVEPFSSPPELPDVMKPQD 103
BLAST of Elongin B vs. Ensembl Nematostella
Match: EDO37366 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SFY6]) HSP 1 Score: 116.316 bits (290), Expect = 1.972e-34 Identity = 60/117 (51.28%), Postives = 83/117 (70.94%), Query Frame = 1 Query: 43 MDVYLMVKRKKTSIFLDCKENSTVMEIKKMIEGILKVQPENQMLYKDKTVMEDTKTVAEYNLNSLTSRAQTPSLLGLCLRDLEIGNFETLEIFPLSVPPELPEVMRTQDQSPLQTGS 393 M+V+LMV+R K SIFLDCKE +TVME+KK IEGI+K PE+Q L+KD +++D KT+ + + T++AQTP+L+GL LR + FE + I LS PPELP+VM+ Q+ GS Sbjct: 1 MEVFLMVRRLKLSIFLDCKEGTTVMELKKKIEGIIKRPPEDQKLFKDDQLLDDNKTLGDCGFTNQTAKAQTPALVGLALRRED--EFEPVTIDALSSPPELPDVMKPQEGISNSDGS 115
BLAST of Elongin B vs. Ensembl Medaka
Match: ELOB (elongin B [Source:NCBI gene;Acc:101169818]) HSP 1 Score: 112.849 bits (281), Expect = 1.464e-32 Identity = 53/109 (48.62%), Postives = 76/109 (69.72%), Query Frame = 1 Query: 43 MDVYLMVKRKKTSIFLDCKENSTVMEIKKMIEGILKVQPENQMLYKDKTVMEDTKTVAEYNLNSLTSRAQTPSLLGLCLRDLEIGNFETLEIFPLSVPPELPEVMRTQD 369 MDV+LM++R KT+IF D KE++TV E+K+++EGILK P++Q LYKD ++ED KT+ + + T+R Q P+ +GL R + FE L I S PPELP+VM+ QD Sbjct: 1 MDVFLMIRRHKTTIFTDAKESTTVYELKRIVEGILKRAPDDQRLYKDDQLLEDNKTLGDCGFTNQTARPQAPATVGLAFRSND-DMFEQLHIEAFSSPPELPDVMKPQD 108
BLAST of Elongin B vs. Planmine SMEST
Match: SMESG000004072.1 (SMESG000004072.1) HSP 1 Score: 243.817 bits (621), Expect = 2.518e-84 Identity = 120/120 (100.00%), Postives = 120/120 (100.00%), Query Frame = 1 Query: 43 MDVYLMVKRKKTSIFLDCKENSTVMEIKKMIEGILKVQPENQMLYKDKTVMEDTKTVAEYNLNSLTSRAQTPSLLGLCLRDLEIGNFETLEIFPLSVPPELPEVMRTQDQSPLQTGSETK 402 MDVYLMVKRKKTSIFLDCKENSTVMEIKKMIEGILKVQPENQMLYKDKTVMEDTKTVAEYNLNSLTSRAQTPSLLGLCLRDLEIGNFETLEIFPLSVPPELPEVMRTQDQSPLQTGSETK Sbjct: 1 MDVYLMVKRKKTSIFLDCKENSTVMEIKKMIEGILKVQPENQMLYKDKTVMEDTKTVAEYNLNSLTSRAQTPSLLGLCLRDLEIGNFETLEIFPLSVPPELPEVMRTQDQSPLQTGSETK 120 The following BLAST results are available for this feature:
BLAST of Elongin B vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of Elongin B vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 1
BLAST of Elongin B vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 1
BLAST of Elongin B vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 4
BLAST of Elongin B vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 1
BLAST of Elongin B vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of Elongin B vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 3
BLAST of Elongin B vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Elongin B vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 3
BLAST of Elongin B vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 0
BLAST of Elongin B vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 0
BLAST of Elongin B vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 1
BLAST of Elongin B vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 1
BLAST of Elongin B vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 1
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30029051 ID=SMED30029051|Name=Elongin B|organism=Schmidtea mediterranea sexual|type=transcript|length=489bpback to top protein sequence of SMED30029051-orf-1 >SMED30029051-orf-1 ID=SMED30029051-orf-1|Name=SMED30029051-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=121bp MDVYLMVKRKKTSIFLDCKENSTVMEIKKMIEGILKVQPENQMLYKDKTVback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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