Lysosomal Pro-X carboxypeptidase

Overview
NameLysosomal Pro-X carboxypeptidase
Smed IDSMED30029010
Length (bp)1722
Neoblast Clusters

Zeng et. al., 2018




▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 



 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)




Explore this single cell expression dataset with our NB Cluster Shiny App




 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Lysosomal Pro-X carboxypeptidase (SMED30029010) t-SNE clustered cells

Violin plots show distribution of expression levels for Lysosomal Pro-X carboxypeptidase (SMED30029010) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Lysosomal Pro-X carboxypeptidase (SMED30029010) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Lysosomal Pro-X carboxypeptidase (SMED30029010) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017




Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020




SMED30029010

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 3

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
parenchymal cellSMED30029010SMESG000074421.1 dd_Smed_v4_10813_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
whole organism asexual adult single-cell RNA-sequencing evidence
epidermal cellSMED30029010SMESG000074421.1 dd_Smed_v4_10813_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
whole organism asexual adult single-cell RNA-sequencing evidence
epidermisSMED30029010SMESG000074421.1 dd_Smed_v4_10813_0_1dd_Smed_v4PMID:28292427
Wurtzel et al., 2017
whole organism asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
BLAST of Lysosomal Pro-X carboxypeptidase vs. Ensembl Human
Match: PRCP (prolylcarboxypeptidase [Source:HGNC Symbol;Acc:HGNC:9344])

HSP 1 Score: 367.466 bits (942), Expect = 7.708e-121
Identity = 175/451 (38.80%), Postives = 274/451 (60.75%), Query Frame = 1
Query:  205 YETRYFQTYVDHFTFKNESLKFNLKYLISTKYWSK-GNVILFYCGNEANIEFFARISGNLWELGEQLSALVVFAEHRYYGSSLPFGNKSFSSAEYFGYLTVEQVIADYATLLTYLKSKITGASKSPVIAFGGSYGGMLAAWLRLKYTNIVAGSISSSAPFLMVGNYKNCNKIFKVISKVYQSQGSKLCAENIRKIWPIIKAINNR-HGLAHLSKIFHLCQPL--KDVETLISFLNNALFEISVANFPYAASVSVPLPAWPVREFCKRYTNGNLSDISNVLTSFYNAIQIYGNSTENSKCLDFQAADKNSFNSMAWEIQTCMELPFPMCINGIHDIYFKENLITEGEFNNFCLKKYGIKPRLNWINILFSGIHFQSLSNIIFSNGLLDPWSAGGILESSNKKIQLIKILNGAHHVDLRKSHPMDTTDIKMARKLEKTTIEKWISEWHEQIAK 1545
            Y   YFQ  VDHF F N    FN +YL++ KYW K G  ILFY GNE +I +F   +G +W++ E+L A++VFAEHRYYG SLPFG+ SF  + +  +LT EQ +AD+A L+ +LK  I GA   PVIA GGSYGGMLAAW R+KY ++V G++++SAP     +   C    K+++  ++  G   C+E+I + W  I  ++N   GL  L+   HLC PL  +D++ L  +++     +++ ++PYA++   PLPAWP++  C+   N N+SD S +L + + A+ +Y N +   KCL+      +S  ++ W  Q C E+  P C NG+ D+ F+ +     E ++ C +++G++PR +WI  ++ G +  S +NI+FSNG LDPWS GG+ +     +  + I  GAHH+DLR  + +D   + +AR LE   ++ WI ++++   K
Sbjct:   48 YSVLYFQQKVDHFGF-NTVKTFNQRYLVADKYWKKNGGSILFYTGNEGDIIWFCNNTGFMWDVAEELKAMLVFAEHRYYGESLPFGDNSFKDSRHLNFLTSEQALADFAELIKHLKRTIPGAENQPVIAIGGSYGGMLAAWFRMKYPHMVVGALAASAPIWQFEDLVPCGVFMKIVTTDFRKSGPH-CSESIHRSWDAINRLSNTGSGLQWLTGALHLCSPLTSQDIQHLKDWISETWVNLAMVDYPYASNFLQPLPAWPIKVVCQYLKNPNVSD-SLLLQNIFQALNVYYNYSGQVKCLNISETATSSLGTLGWSYQACTEVVMPFCTNGVDDM-FEPHSWNLKELSDDCFQQWGVRPRPSWITTMYGGKNISSHTNIVFSNGELDPWSGGGVTKDITDTLVAVTISEGAHHLDLRTKNALDPMSVLLARSLEVRHMKNWIRDFYDSAGK 494          
BLAST of Lysosomal Pro-X carboxypeptidase vs. Ensembl Human
Match: PRCP (prolylcarboxypeptidase [Source:HGNC Symbol;Acc:HGNC:9344])

HSP 1 Score: 360.147 bits (923), Expect = 8.653e-118
Identity = 172/448 (38.39%), Postives = 271/448 (60.49%), Query Frame = 1
Query:  214 RYFQTYVDHFTFKNESLKFNLKYLISTKYWSK-GNVILFYCGNEANIEFFARISGNLWELGEQLSALVVFAEHRYYGSSLPFGNKSFSSAEYFGYLTVEQVIADYATLLTYLKSKITGASKSPVIAFGGSYGGMLAAWLRLKYTNIVAGSISSSAPFLMVGNYKNCNKIFKVISKVYQSQGSKLCAENIRKIWPIIKAINNR-HGLAHLSKIFHLCQPL--KDVETLISFLNNALFEISVANFPYAASVSVPLPAWPVREFCKRYTNGNLSDISNVLTSFYNAIQIYGNSTENSKCLDFQAADKNSFNSMAWEIQTCMELPFPMCINGIHDIYFKENLITEGEFNNFCLKKYGIKPRLNWINILFSGIHFQSLSNIIFSNGLLDPWSAGGILESSNKKIQLIKILNGAHHVDLRKSHPMDTTDIKMARKLEKTTIEKWISEWHEQIAK 1545
             Y    VDHF F N    FN +YL++ KYW K G  ILFY GNE +I +F   +G +W++ E+L A++VFAEHRYYG SLPFG+ SF  + +  +LT EQ +AD+A L+ +LK  I GA   PVIA GGSYGGMLAAW R+KY ++V G++++SAP     +   C    K+++  ++  G   C+E+I + W  I  ++N   GL  L+   HLC PL  +D++ L  +++     +++ ++PYA++   PLPAWP++  C+   N N+SD S +L + + A+ +Y N +   KCL+      +S  ++ W  Q C E+  P C NG+ D+ F+ +     E ++ C +++G++PR +WI  ++ G +  S +NI+FSNG LDPWS GG+ +     +  + I  GAHH+DLR  + +D   + +AR LE   ++ WI ++++   K
Sbjct:   72 HYKTPLVDHFGF-NTVKTFNQRYLVADKYWKKNGGSILFYTGNEGDIIWFCNNTGFMWDVAEELKAMLVFAEHRYYGESLPFGDNSFKDSRHLNFLTSEQALADFAELIKHLKRTIPGAENQPVIAIGGSYGGMLAAWFRMKYPHMVVGALAASAPIWQFEDLVPCGVFMKIVTTDFRKSGPH-CSESIHRSWDAINRLSNTGSGLQWLTGALHLCSPLTSQDIQHLKDWISETWVNLAMVDYPYASNFLQPLPAWPIKVVCQYLKNPNVSD-SLLLQNIFQALNVYYNYSGQVKCLNISETATSSLGTLGWSYQACTEVVMPFCTNGVDDM-FEPHSWNLKELSDDCFQQWGVRPRPSWITTMYGGKNISSHTNIVFSNGELDPWSGGGVTKDITDTLVAVTISEGAHHLDLRTKNALDPMSVLLARSLEVRHMKNWIRDFYDSAGK 515          
BLAST of Lysosomal Pro-X carboxypeptidase vs. Ensembl Human
Match: DPP7 (dipeptidyl peptidase 7 [Source:HGNC Symbol;Acc:HGNC:14892])

HSP 1 Score: 298.13 bits (762), Expect = 4.565e-94
Identity = 169/452 (37.39%), Postives = 253/452 (55.97%), Query Frame = 1
Query:  205 YETRYFQTYVDHFTFKNESLK-FNLKYLISTKYWSKG-NVILFYCGNEANIEFFARISGNLWELGEQLSALVVFAEHRYYGSSLPFGNKSFSSAEYFGYLTVEQVIADYATLLTYLKSKITGASKSPVIAFGGSYGGMLAAWLRLKYTNIVAGSISSSAPFLMVGNYKNCNKIFKVISKVYQSQGSKLCAENIRKIWPIIKAINNRHGLAHLSKIFHLCQPL---KDVETLISFLNNALFEISVANFPYAASVSVPLPAWPVREFCKRYTNGNLSDISNVLTSFYNAIQIYGNSTENSKCLDF-----QAADKNSF----NSMAWEIQTCMELPFPMCINGIHDIYFKENLITEGEFNNFCLKKYGIKPRLNWINILFSGIHFQSLSNIIFSNGLLDPWSAGGILESSNKKIQLIKILNGAHHVDLRKSHPMDTTDIKMARKLEKTTIEKWI 1518
            ++ R+FQ  +DHF F+    K F  ++L+S ++W +G   I FY GNE ++  FA  S  + EL  +  AL+VFAEHRYYG SLPFG +S +   +   LTVEQ +AD+A LL  L+  + GA  +P IAFGGSYGGML+A+LR+KY ++VAG++++SAP L V    + N+ F+ ++  ++ Q  K C + +R+ +  IK +  +     +   F  CQPL   KD+  L  F  NA   +++ ++PY      PLPA PV+  C R     LS+   +      A  +Y N++ +  C D        AD        ++ AW+ Q C E+      N + D+ F +   T+     +CL  +G+ PR +W+   F G   ++ SNIIFSNG LDPW+ GGI  + +  +  + I  GAHH+DLR SHP D   +  ARKLE T I +W+
Sbjct:   31 FQERFFQQRLDHFNFERFGNKTFPQRFLVSDRFWVRGEGPIFFYTGNEGDVWAFANNSAFVAELAAERGALLVFAEHRYYGKSLPFGAQS-TQRGHTELLTVEQALADFAELLRALRRDL-GAQDAPAIAFGGSYGGMLSAYLRMKYPHLVAGALAASAPVLAVAGLGDSNQFFRDVTADFEGQSPK-CTQGVREAFRQIKDLFLQGAYDTVRWEFGTCQPLSDEKDLTQLFMFARNAFTVLAMMDYPYPTDFLGPLPANPVKVGCDRL----LSEAQRITGLRALAGLVY-NASGSEHCYDIYRLYHSCADPTGCGTGPDARAWDYQACTEINLTFASNNVTDM-FPDLPFTDELRQRYCLDTWGVWPRPDWLLTSFWGGDLRAASNIIFSNGNLDPWAGGGIRRNLSASVIAVTIQGGAHHLDLRASHPEDPASVVEARKLEATIIGEWV 473          
BLAST of Lysosomal Pro-X carboxypeptidase vs. Ensembl Human
Match: PRCP (prolylcarboxypeptidase [Source:HGNC Symbol;Acc:HGNC:9344])

HSP 1 Score: 201.06 bits (510), Expect = 3.229e-60
Identity = 94/233 (40.34%), Postives = 149/233 (63.95%), Query Frame = 1
Query:  379 LWELGEQLSALVVFAEHRYYGSSLPFGNKSFSSAEYFGYLTVEQVIADYATLLTYLKSKITGASKSPVIAFGGSYGGMLAAWLRLKYTNIVAGSISSSAPFLMVGNYKNCNKIFKVISKVYQSQGSKLCAENIRKIWPIIKAINNR-HGLAHLSKIFHLCQPL--KDVETLISFLNNALFEISVANFPYAASVSVPLPAWPVREFCKRYTNGNLSDISNVLTSFYNAIQIYGN 1068
            +W++ E+L A++VFAEHRYYG SLPFG+ SF  + +  +LT EQ +AD+A L+ +LK  I GA   PVIA GGSYGGMLAAW R+KY ++V G++++SAP     +   C    K+++  ++  G   C+E+I + W  I  ++N   GL  L+   HLC PL  +D++ L  +++     +++ ++PYA++   PLPAWP++  C+   N N+SD S +L + + A+ +Y N
Sbjct:    1 MWDVAEELKAMLVFAEHRYYGESLPFGDNSFKDSRHLNFLTSEQALADFAELIKHLKRTIPGAENQPVIAIGGSYGGMLAAWFRMKYPHMVVGALAASAPIWQFEDLVPCGVFMKIVTTDFRKSGPH-CSESIHRSWDAINRLSNTGSGLQWLTGALHLCSPLTSQDIQHLKDWISETWVNLAMVDYPYASNFLQPLPAWPIKVVCQYLKNPNVSD-SLLLQNIFQALNVYYN 231          
BLAST of Lysosomal Pro-X carboxypeptidase vs. Ensembl Human
Match: PRCP (prolylcarboxypeptidase [Source:HGNC Symbol;Acc:HGNC:9344])

HSP 1 Score: 170.244 bits (430), Expect = 1.476e-49
Identity = 80/149 (53.69%), Postives = 107/149 (71.81%), Query Frame = 1
Query:  232 VDHFTFKNESLKFNLKYLISTKYWSK-GNVILFYCGNEANIEFFARISGNLWELGEQLSALVVFAEHRYYGSSLPFGNKSFSSAEYFGYLTVEQVIADYATLLTYLKSKITGASKSPVIAFGGSYGGMLAAWLRLKYTNIVAGSISSSA 675
            VDHF F N    FN +YL++ KYW K G  ILFY GNE +I +F   +G +W++ E+L A++VFAEHRYYG SLPFG+ SF  + +  +LT EQ +AD+A L+ +LK  I GA   PVIA GGSYGGMLAAW R+KY ++V G++++SA
Sbjct:   16 VDHFGF-NTVKTFNQRYLVADKYWKKNGGSILFYTGNEGDIIWFCNNTGFMWDVAEELKAMLVFAEHRYYGESLPFGDNSFKDSRHLNFLTSEQALADFAELIKHLKRTIPGAENQPVIAIGGSYGGMLAAWFRMKYPHMVVGALAASA 163          
BLAST of Lysosomal Pro-X carboxypeptidase vs. Ensembl Celegans
Match: pcp-5 (Prolyl carboxy peptidase like protein 5 [Source:UniProtKB/Swiss-Prot;Acc:P34676])

HSP 1 Score: 292.352 bits (747), Expect = 4.252e-92
Identity = 169/501 (33.73%), Postives = 270/501 (53.89%), Query Frame = 1
Query:   97 MKLYLFLIQMHCL-FLQQSFSYNKSKEIDKLSNYKLTYETRYFQTYVDHFTFKNESLKFNLKYLISTKYWSKGNVILFYCGNEANIEFFARISGNLWELGEQLSALVVFAEHRYYGSSLPFGNKSFSSAEYFGYLTVEQVIADYATLLTYLKS-KITGASKSPVIAFGGSYGGMLAAWLRLKYTNIVAGSISSSAPFLMVGNYKNCNKIFK-VISKVYQSQGSKLCAENIRKIWPIIKAI-NNRHGLAHLSKIFHLCQPLK-----DVETLISFLNNALFEISVANFPYAASVSVPLPAWPVREFCKRYTNGNLSDISNVLTSFYNAIQIYGNSTENSKCLDFQAADKNSF-----NSMAWEIQTCMELPFPMCINGI-HDIYFKENLITEGEFNNFCLKKYG--------IKPRLNWINILFSGIHFQSLSNIIFSNGLLDPWSAGGILESSNKKIQLIKIL--NGAHHVDLRKSHPMDTTDIKMARKLEKTTIEKWISE 1524
            + L + +   HCL  L+   + N + + +K S  K  YE  Y +  +D F F N+ L+F+L+Y ++  ++  G  ILFY GNE ++E FA  +G +W+L  +L A VVF EHR+YG S PF N+S++   + GYL+ +Q +AD+A  + + K+ KI GA KS VIAFGGSYGGML+AW R+KY +IV G+I++SAP     +      ++  ++++ +   G    A  I K W  +  +  +  G  +L+ ++ L    K     D+  L  ++  ++  +++ N+PY  S    LPAWPV+E CK  +    +   +     Y  + +Y N T +       AA  +S      + + W  QTC E+  P+C +G  +D ++K+   T  ++  FC++ +         ++P      + F      S SNI+FSNG LDPWS GG   S   +  +I ++   GAHH DLR +HP DT ++K  R +E   I+KWI E
Sbjct:    5 ISLAILIATTHCLTLLRDPVTQNGASKFEK-SIGKYKYEEGYLKAPIDPFAFTND-LEFDLRYFLNIDHYETGGPILFYTGNEGSLEAFAENTGFMWDLAPELKAAVVFVEHRFYGKSQPFKNESYTDIRHLGYLSSQQALADFALSVQFFKNEKIKGAQKSAVIAFGGSYGGMLSAWFRIKYPHIVDGAIAASAPVFWFTDSNIPEDVYDFIVTRAFLDAGCNRKA--IEKGWIALDELAKSDSGRQYLNVLYKLDPKSKLENKDDIGFLKQYIRESMEAMAMVNYPYPTSFLSSLPAWPVKEACKSASQPGKTQEESA-EQLYKIVNLYYNYTGDKSTHCANAAKCDSAYGSLGDPLGWPFQTCTEMVMPLCGSGYPNDFFWKDCPFTSEKYAEFCMQTFSSIHYNKTLLRPLAG--GLAFGATSLPSASNIVFSNGYLDPWSGGGYDHSDKVQGSVISVILKQGAHHYDLRGAHPQDTEEVKKVRAMETQAIKKWIKE 498          
BLAST of Lysosomal Pro-X carboxypeptidase vs. Ensembl Celegans
Match: pcp-5 (Prolyl carboxy peptidase like protein 5 [Source:UniProtKB/Swiss-Prot;Acc:P34676])

HSP 1 Score: 292.352 bits (747), Expect = 4.252e-92
Identity = 169/501 (33.73%), Postives = 270/501 (53.89%), Query Frame = 1
Query:   97 MKLYLFLIQMHCL-FLQQSFSYNKSKEIDKLSNYKLTYETRYFQTYVDHFTFKNESLKFNLKYLISTKYWSKGNVILFYCGNEANIEFFARISGNLWELGEQLSALVVFAEHRYYGSSLPFGNKSFSSAEYFGYLTVEQVIADYATLLTYLKS-KITGASKSPVIAFGGSYGGMLAAWLRLKYTNIVAGSISSSAPFLMVGNYKNCNKIFK-VISKVYQSQGSKLCAENIRKIWPIIKAI-NNRHGLAHLSKIFHLCQPLK-----DVETLISFLNNALFEISVANFPYAASVSVPLPAWPVREFCKRYTNGNLSDISNVLTSFYNAIQIYGNSTENSKCLDFQAADKNSF-----NSMAWEIQTCMELPFPMCINGI-HDIYFKENLITEGEFNNFCLKKYG--------IKPRLNWINILFSGIHFQSLSNIIFSNGLLDPWSAGGILESSNKKIQLIKIL--NGAHHVDLRKSHPMDTTDIKMARKLEKTTIEKWISE 1524
            + L + +   HCL  L+   + N + + +K S  K  YE  Y +  +D F F N+ L+F+L+Y ++  ++  G  ILFY GNE ++E FA  +G +W+L  +L A VVF EHR+YG S PF N+S++   + GYL+ +Q +AD+A  + + K+ KI GA KS VIAFGGSYGGML+AW R+KY +IV G+I++SAP     +      ++  ++++ +   G    A  I K W  +  +  +  G  +L+ ++ L    K     D+  L  ++  ++  +++ N+PY  S    LPAWPV+E CK  +    +   +     Y  + +Y N T +       AA  +S      + + W  QTC E+  P+C +G  +D ++K+   T  ++  FC++ +         ++P      + F      S SNI+FSNG LDPWS GG   S   +  +I ++   GAHH DLR +HP DT ++K  R +E   I+KWI E
Sbjct:    5 ISLAILIATTHCLTLLRDPVTQNGASKFEK-SIGKYKYEEGYLKAPIDPFAFTND-LEFDLRYFLNIDHYETGGPILFYTGNEGSLEAFAENTGFMWDLAPELKAAVVFVEHRFYGKSQPFKNESYTDIRHLGYLSSQQALADFALSVQFFKNEKIKGAQKSAVIAFGGSYGGMLSAWFRIKYPHIVDGAIAASAPVFWFTDSNIPEDVYDFIVTRAFLDAGCNRKA--IEKGWIALDELAKSDSGRQYLNVLYKLDPKSKLENKDDIGFLKQYIRESMEAMAMVNYPYPTSFLSSLPAWPVKEACKSASQPGKTQEESA-EQLYKIVNLYYNYTGDKSTHCANAAKCDSAYGSLGDPLGWPFQTCTEMVMPLCGSGYPNDFFWKDCPFTSEKYAEFCMQTFSSIHYNKTLLRPLAG--GLAFGATSLPSASNIVFSNGYLDPWSGGGYDHSDKVQGSVISVILKQGAHHYDLRGAHPQDTEEVKKVRAMETQAIKKWIKE 498          
BLAST of Lysosomal Pro-X carboxypeptidase vs. Ensembl Celegans
Match: pcp-5 (Prolyl carboxy peptidase like protein 5 [Source:UniProtKB/Swiss-Prot;Acc:P34676])

HSP 1 Score: 291.582 bits (745), Expect = 3.896e-91
Identity = 169/501 (33.73%), Postives = 270/501 (53.89%), Query Frame = 1
Query:   97 MKLYLFLIQMHCL-FLQQSFSYNKSKEIDKLSNYKLTYETRYFQTYVDHFTFKNESLKFNLKYLISTKYWSKGNVILFYCGNEANIEFFARISGNLWELGEQLSALVVFAEHRYYGSSLPFGNKSFSSAEYFGYLTVEQVIADYATLLTYLKS-KITGASKSPVIAFGGSYGGMLAAWLRLKYTNIVAGSISSSAPFLMVGNYKNCNKIFK-VISKVYQSQGSKLCAENIRKIWPIIKAI-NNRHGLAHLSKIFHLCQPLK-----DVETLISFLNNALFEISVANFPYAASVSVPLPAWPVREFCKRYTNGNLSDISNVLTSFYNAIQIYGNSTENSKCLDFQAADKNSF-----NSMAWEIQTCMELPFPMCINGI-HDIYFKENLITEGEFNNFCLKKYG--------IKPRLNWINILFSGIHFQSLSNIIFSNGLLDPWSAGGILESSNKKIQLIKIL--NGAHHVDLRKSHPMDTTDIKMARKLEKTTIEKWISE 1524
            + L + +   HCL  L+   + N + + +K S  K  YE  Y +  +D F F N+ L+F+L+Y ++  ++  G  ILFY GNE ++E FA  +G +W+L  +L A VVF EHR+YG S PF N+S++   + GYL+ +Q +AD+A  + + K+ KI GA KS VIAFGGSYGGML+AW R+KY +IV G+I++SAP     +      ++  ++++ +   G    A  I K W  +  +  +  G  +L+ ++ L    K     D+  L  ++  ++  +++ N+PY  S    LPAWPV+E CK  +    +   +     Y  + +Y N T +       AA  +S      + + W  QTC E+  P+C +G  +D ++K+   T  ++  FC++ +         ++P      + F      S SNI+FSNG LDPWS GG   S   +  +I ++   GAHH DLR +HP DT ++K  R +E   I+KWI E
Sbjct:   66 ISLAILIATTHCLTLLRDPVTQNGASKFEK-SIGKYKYEEGYLKAPIDPFAFTND-LEFDLRYFLNIDHYETGGPILFYTGNEGSLEAFAENTGFMWDLAPELKAAVVFVEHRFYGKSQPFKNESYTDIRHLGYLSSQQALADFALSVQFFKNEKIKGAQKSAVIAFGGSYGGMLSAWFRIKYPHIVDGAIAASAPVFWFTDSNIPEDVYDFIVTRAFLDAGCNRKA--IEKGWIALDELAKSDSGRQYLNVLYKLDPKSKLENKDDIGFLKQYIRESMEAMAMVNYPYPTSFLSSLPAWPVKEACKSASQPGKTQEESA-EQLYKIVNLYYNYTGDKSTHCANAAKCDSAYGSLGDPLGWPFQTCTEMVMPLCGSGYPNDFFWKDCPFTSEKYAEFCMQTFSSIHYNKTLLRPLAG--GLAFGATSLPSASNIVFSNGYLDPWSGGGYDHSDKVQGSVISVILKQGAHHYDLRGAHPQDTEEVKKVRAMETQAIKKWIKE 559          
BLAST of Lysosomal Pro-X carboxypeptidase vs. Ensembl Celegans
Match: pcp-1 (Putative serine protease pcp-1 [Source:UniProtKB/Swiss-Prot;Acc:P34610])

HSP 1 Score: 214.542 bits (545), Expect = 5.485e-62
Identity = 150/485 (30.93%), Postives = 239/485 (49.28%), Query Frame = 1
Query:  232 VDHFTFKNESLKFNLKYLISTKYWSKGNVILFYCGNEANIEFFARISGNLWELGEQLSALVVFAEHRYYGSSLPFGNKSFSSAEYFGYLTVEQVIADYATLLTYLKS-----KITGASKSPVIAFGGSYGGMLAAWLRLKYTNIVAGSISSSAPFL-MVGNYKNCNKIFKVISKVYQSQG-SKLCAENIRKIWPIIKAINNRHGLAHLSKIFHLCQPLK-----DVETLISFLNNALFEISVANFPYAASVSVPLPAWPVREFCKRYTNGNLSDIS--NVLTSFYNAIQIYGNSTENSK---CLDFQ-----AADKNSFNSMAWEIQTCMELPFPMCIN-GIHDIYFKE------NLITEGEFNNFCLKKYGIKPRLNW----INILFSGIHFQSLSNIIFSNGLLDPWSAGGILESSN---KKIQLIKILNGAHHVDLRKSHPMDTTDIKMARKLEKTTIEKWISEWHEQIAKIYLL*NFCVSN 1578
            +DHFT+  ++  F+++ + +  ++  G  I FY GNE  +E F   +G +++L    +A ++FAEHR+YG + PFGN+S++S    GYLT EQ +ADYA LLT LK      K+T  + + VI+FGGSYGGML+AW R KY +IV G+ + SAP + M G   +      + S+ Y   G ++    N       + + +      + + +F L    K     D   L ++L  A+  +++ ++PY      PLPAWPV   C  Y N N +  S  +++ +  NA  IY N   +     C+DF             + + W  Q C E+   MC + G +D+++ E        + +G  + F  K  G  P+ NW    +  L+ G      SN+I + G LDPWS GG     N   + I +++I   AHH+DLR+ +  D   +  AR      ++ W+      I  I  L +  + N
Sbjct:   51 LDHFTW-GDTRTFDMRVMWNNTFYKPGGPIFFYTGNEGGLESFVTATGMMFDLAPMFNASIIFAEHRFYGQTQPFGNQSYASLANVGYLTSEQALADYAELLTELKRDNNQFKMTFPAATQVISFGGSYGGMLSAWFRQKYPHIVKGAWAGSAPLIYMNGGGVDPGAFDHITSRTYIDNGCNRFILANAWNATLNLSSTDAGRQWLNNNTVFKLDPRTKIRNQTDGWNLNAYLREAIEYMAMVDYPYPTGFLEPLPAWPVTVACG-YMNANGTSFSDKDLVKAVANAANIYYNYNRDPNFTYCIDFSICGDQGTGGLGGDELGWPWQECSEIIMAMCASGGSNDVFWNECGKDIYQTLQQGCVSIF--KSMGWTPK-NWNIDAVKTLY-GYDLSGSSNLILTQGHLDPWSGGGYKVDQNNAARGIYVLEIPGSAHHLDLRQPNTCDPNTVTNARFQIIQILKCWVDPNCNTIPTISPLPSISIPN 529          
BLAST of Lysosomal Pro-X carboxypeptidase vs. Ensembl Celegans
Match: pcp-1 (Putative serine protease pcp-1 [Source:UniProtKB/Swiss-Prot;Acc:P34610])

HSP 1 Score: 214.542 bits (545), Expect = 5.485e-62
Identity = 150/485 (30.93%), Postives = 239/485 (49.28%), Query Frame = 1
Query:  232 VDHFTFKNESLKFNLKYLISTKYWSKGNVILFYCGNEANIEFFARISGNLWELGEQLSALVVFAEHRYYGSSLPFGNKSFSSAEYFGYLTVEQVIADYATLLTYLKS-----KITGASKSPVIAFGGSYGGMLAAWLRLKYTNIVAGSISSSAPFL-MVGNYKNCNKIFKVISKVYQSQG-SKLCAENIRKIWPIIKAINNRHGLAHLSKIFHLCQPLK-----DVETLISFLNNALFEISVANFPYAASVSVPLPAWPVREFCKRYTNGNLSDIS--NVLTSFYNAIQIYGNSTENSK---CLDFQ-----AADKNSFNSMAWEIQTCMELPFPMCIN-GIHDIYFKE------NLITEGEFNNFCLKKYGIKPRLNW----INILFSGIHFQSLSNIIFSNGLLDPWSAGGILESSN---KKIQLIKILNGAHHVDLRKSHPMDTTDIKMARKLEKTTIEKWISEWHEQIAKIYLL*NFCVSN 1578
            +DHFT+  ++  F+++ + +  ++  G  I FY GNE  +E F   +G +++L    +A ++FAEHR+YG + PFGN+S++S    GYLT EQ +ADYA LLT LK      K+T  + + VI+FGGSYGGML+AW R KY +IV G+ + SAP + M G   +      + S+ Y   G ++    N       + + +      + + +F L    K     D   L ++L  A+  +++ ++PY      PLPAWPV   C  Y N N +  S  +++ +  NA  IY N   +     C+DF             + + W  Q C E+   MC + G +D+++ E        + +G  + F  K  G  P+ NW    +  L+ G      SN+I + G LDPWS GG     N   + I +++I   AHH+DLR+ +  D   +  AR      ++ W+      I  I  L +  + N
Sbjct:   51 LDHFTW-GDTRTFDMRVMWNNTFYKPGGPIFFYTGNEGGLESFVTATGMMFDLAPMFNASIIFAEHRFYGQTQPFGNQSYASLANVGYLTSEQALADYAELLTELKRDNNQFKMTFPAATQVISFGGSYGGMLSAWFRQKYPHIVKGAWAGSAPLIYMNGGGVDPGAFDHITSRTYIDNGCNRFILANAWNATLNLSSTDAGRQWLNNNTVFKLDPRTKIRNQTDGWNLNAYLREAIEYMAMVDYPYPTGFLEPLPAWPVTVACG-YMNANGTSFSDKDLVKAVANAANIYYNYNRDPNFTYCIDFSICGDQGTGGLGGDELGWPWQECSEIIMAMCASGGSNDVFWNECGKDIYQTLQQGCVSIF--KSMGWTPK-NWNIDAVKTLY-GYDLSGSSNLILTQGHLDPWSGGGYKVDQNNAARGIYVLEIPGSAHHLDLRQPNTCDPNTVTNARFQIIQILKCWVDPNCNTIPTISPLPSISIPN 529          
BLAST of Lysosomal Pro-X carboxypeptidase vs. Ensembl Fly
Match: CG2493 (gene:FBgn0032864 transcript:FBtr0081363)

HSP 1 Score: 342.428 bits (877), Expect = 1.049e-111
Identity = 173/453 (38.19%), Postives = 280/453 (61.81%), Query Frame = 1
Query:  196 KLTYETRYFQTYVDHFTFKNESLKFNLKYLISTKYWSKGNV---ILFYCGNEANIEFFARISGNLWELGEQLSALVVFAEHRYYGSSLPFGNKSFSSA--EYFGYLTVEQVIADYATLLTYLKSKITGASKSPVIAFGGSYGGMLAAWLRLKYTNIVAGSISSSAPFLMVGNYKNCNKIFKVISKVYQSQGSKLCAENIRKIWPIIKAIN-NRHGLAHLSKIFHLCQPLK---DVETLISFLNNALFEISVANFPYAASVSVPLPAWPVREFCKRYTNGNLSDISNVLTSFYNAIQIYGNSTENSKCLDFQAADKNSFNSMAWEIQTCMELPFPMCINGIHDIYFKENLITEGEFNNFCLKKYGIKPRLNWINILFSGIHFQSLSNIIFSNGLLDPWSAGGILESSNKKIQLIKILNGAHHVDLRKSHPMDTTDIKMARKLEKTTIEKWISEW 1527
            +  YE + FQ  +DHF+F   +  FN++YL +  +  K N    I FY GNE +IE FA+ +G LWE  E+  ALV+FAEHRYYG SLPFG+ +F+++  E+  Y TVEQ + DYA L+T+L++      + PV+AFGGSYGGMLAAW R+KY ++V G++++SAP L      +C+  +++++ V+Q+  ++ C  NI K W + + +  +  G   +S  FHLC  LK   D++  + ++      +++ N+PY +S   PLPA+PVR+ C      + +D +++L +  +A+ +Y N T+++KCLD  + + N+ +S  W IQ+C ++  P+C NG  +  F+ +     ++   C K Y + P+   I + + G + ++ +NIIFSNGLLDPWS GG+L++ N K+ +I +  GAHH+DLR S P D   ++ AR  E   I +WI ++
Sbjct:   32 RFKYEIKEFQVPLDHFSFLINA-TFNIRYLYNDSFVDKSNARTPIFFYTGNEGDIELFAQNTGFLWEQAERQRALVIFAEHRYYGKSLPFGSSTFNTSLPEHLAYFTVEQTLEDYAMLITFLRND----RQMPVVAFGGSYGGMLAAWFRMKYPHLVNGALAASAPVLQFPGITDCDIFYRIVTSVFQNAYNENCTLNIAKSWKLFETLGASEAGKKQISDAFHLCNALKNDDDLKKFLDYVEEVYSNLAMVNYPYNSSFLAPLPAYPVRQVCYYLKELHSTD-ADLLHAMSSALAVYTNYTQSAKCLDI-SVNSNADDS-GWNIQSCNQMVMPICSNG-SETMFRTSSWNFKDYAEKCYKNYRLTPKPYDIILRYGGRNLEAATNIIFSNGLLDPWSGGGVLQAPNDKVFVIILPEGAHHLDLRHSDPADPPSVRDARDKEAAIIARWIQDF 475          
BLAST of Lysosomal Pro-X carboxypeptidase vs. Ensembl Fly
Match: CG2493 (gene:FBgn0032864 transcript:FBtr0332970)

HSP 1 Score: 342.428 bits (877), Expect = 1.049e-111
Identity = 173/453 (38.19%), Postives = 280/453 (61.81%), Query Frame = 1
Query:  196 KLTYETRYFQTYVDHFTFKNESLKFNLKYLISTKYWSKGNV---ILFYCGNEANIEFFARISGNLWELGEQLSALVVFAEHRYYGSSLPFGNKSFSSA--EYFGYLTVEQVIADYATLLTYLKSKITGASKSPVIAFGGSYGGMLAAWLRLKYTNIVAGSISSSAPFLMVGNYKNCNKIFKVISKVYQSQGSKLCAENIRKIWPIIKAIN-NRHGLAHLSKIFHLCQPLK---DVETLISFLNNALFEISVANFPYAASVSVPLPAWPVREFCKRYTNGNLSDISNVLTSFYNAIQIYGNSTENSKCLDFQAADKNSFNSMAWEIQTCMELPFPMCINGIHDIYFKENLITEGEFNNFCLKKYGIKPRLNWINILFSGIHFQSLSNIIFSNGLLDPWSAGGILESSNKKIQLIKILNGAHHVDLRKSHPMDTTDIKMARKLEKTTIEKWISEW 1527
            +  YE + FQ  +DHF+F   +  FN++YL +  +  K N    I FY GNE +IE FA+ +G LWE  E+  ALV+FAEHRYYG SLPFG+ +F+++  E+  Y TVEQ + DYA L+T+L++      + PV+AFGGSYGGMLAAW R+KY ++V G++++SAP L      +C+  +++++ V+Q+  ++ C  NI K W + + +  +  G   +S  FHLC  LK   D++  + ++      +++ N+PY +S   PLPA+PVR+ C      + +D +++L +  +A+ +Y N T+++KCLD  + + N+ +S  W IQ+C ++  P+C NG  +  F+ +     ++   C K Y + P+   I + + G + ++ +NIIFSNGLLDPWS GG+L++ N K+ +I +  GAHH+DLR S P D   ++ AR  E   I +WI ++
Sbjct:   32 RFKYEIKEFQVPLDHFSFLINA-TFNIRYLYNDSFVDKSNARTPIFFYTGNEGDIELFAQNTGFLWEQAERQRALVIFAEHRYYGKSLPFGSSTFNTSLPEHLAYFTVEQTLEDYAMLITFLRND----RQMPVVAFGGSYGGMLAAWFRMKYPHLVNGALAASAPVLQFPGITDCDIFYRIVTSVFQNAYNENCTLNIAKSWKLFETLGASEAGKKQISDAFHLCNALKNDDDLKKFLDYVEEVYSNLAMVNYPYNSSFLAPLPAYPVRQVCYYLKELHSTD-ADLLHAMSSALAVYTNYTQSAKCLDI-SVNSNADDS-GWNIQSCNQMVMPICSNG-SETMFRTSSWNFKDYAEKCYKNYRLTPKPYDIILRYGGRNLEAATNIIFSNGLLDPWSGGGVLQAPNDKVFVIILPEGAHHLDLRHSDPADPPSVRDARDKEAAIIARWIQDF 475          
BLAST of Lysosomal Pro-X carboxypeptidase vs. Ensembl Fly
Match: CG3734 (gene:FBgn0038700 transcript:FBtr0339152)

HSP 1 Score: 126.331 bits (316), Expect = 7.564e-31
Identity = 118/493 (23.94%), Postives = 202/493 (40.97%), Query Frame = 1
Query:  109 LFLIQMHCLFLQQSFSY-NKSKEIDKLSNYKLTYETRYFQTYVDHFTFKNESLKFNLKYLISTKYWSKGNVILFYCGNEANIEFFARISGNLWELGEQLSALVVFAEHRYYGSSLPFGNKSFSSAEYFGYLTVEQVIADYATLLTYLKSKITGASKSPVIAFGGSYGGMLAAWLRLKYTNIVAGSISSSAPFLMVGNYKNCNKIFKVISKVYQSQGSKLCAENIRK-IWPIIKAINNRHGLAHLSKIFHLCQPLK-----DVETLISFLNNALFEISVANFPYAASVSVPLPAWPVREFCKRYTNGNLSDISNVLTSFYNAIQIYGNSTENSKCLDFQ---------AADKNSFNSMAWEIQTCMELPFPMCINGIHDIYFKENLITEGEFNNFCLKKYG-------IKPRLNWINILFSGIHFQSLSNIIFSNGLLDPWSAGGILESSNKKIQLIKILNGAHHVDLRKSHPMDTTDIKMARKLEKTTIEKWI 1518
            L L Q H    +++F   ++   +    N     +T + +  +DHF    E+  + ++Y+++   +  G  +  Y G E  I       G+L+++ ++ +AL+ + EHRYYG S P  + S    E   YL V Q +AD A  +  +K    G S S VI  GGSY   +  W +  Y ++VAG  +SSAP L   N+    +I     +  +  G   C + I   I  +   I  + G A +  +  LC+P       DV TL S +++             A V     A  +   C++   G+ +D+  V     +  +  G      KC D             + N      W  QTC E  +          +  +  +T   +   C   YG       I  +++  N  F G+ F ++ N+  ++G LDPW A GI + +   I    I   AH  D       DT +++ +++     + +W+
Sbjct:   12 LALGQTHGSIFERTFKRIHEEPPLPTTQNRADVVQTLWIEQKLDHFD-PEETRTWQMRYMLNDALYQSGAPLFIYLGGEWEISSGRITGGHLYDMAKEHNALLAYTEHRYYGQSKPLPDLS---NENIKYLNVNQSLADLAYFINTIKQNHEGLSDSKVIIVGGSYSATMVTWFKKLYPDLVAGGWASSAPLLAKVNFVEYKEI---TGQSIEQMGGSACYKRIENGIAEMETMIATKRG-AEVKALLKLCEPFDVYSDLDVWTLFSEISDIF-----------AGVVQTHNAGQIEGVCEKIMAGS-NDLIGVAGYLLDVFEESG-----GKCYDLSYDAITALLLDTNYNGNIMRQWIFQTCNEYGWYQTSGSSAQPFGTKFPVT--YYTTMCADLYGSEYSNEFISNQVSITNQFFGGL-FPNVENVYLTHGQLDPWRAMGIQDETQATI----IPEHAHCKDFNSISSSDTAEMRASKERIAELVREWV 472          
BLAST of Lysosomal Pro-X carboxypeptidase vs. Ensembl Fly
Match: CG3734 (gene:FBgn0038700 transcript:FBtr0083755)

HSP 1 Score: 126.331 bits (316), Expect = 7.564e-31
Identity = 118/493 (23.94%), Postives = 202/493 (40.97%), Query Frame = 1
Query:  109 LFLIQMHCLFLQQSFSY-NKSKEIDKLSNYKLTYETRYFQTYVDHFTFKNESLKFNLKYLISTKYWSKGNVILFYCGNEANIEFFARISGNLWELGEQLSALVVFAEHRYYGSSLPFGNKSFSSAEYFGYLTVEQVIADYATLLTYLKSKITGASKSPVIAFGGSYGGMLAAWLRLKYTNIVAGSISSSAPFLMVGNYKNCNKIFKVISKVYQSQGSKLCAENIRK-IWPIIKAINNRHGLAHLSKIFHLCQPLK-----DVETLISFLNNALFEISVANFPYAASVSVPLPAWPVREFCKRYTNGNLSDISNVLTSFYNAIQIYGNSTENSKCLDFQ---------AADKNSFNSMAWEIQTCMELPFPMCINGIHDIYFKENLITEGEFNNFCLKKYG-------IKPRLNWINILFSGIHFQSLSNIIFSNGLLDPWSAGGILESSNKKIQLIKILNGAHHVDLRKSHPMDTTDIKMARKLEKTTIEKWI 1518
            L L Q H    +++F   ++   +    N     +T + +  +DHF    E+  + ++Y+++   +  G  +  Y G E  I       G+L+++ ++ +AL+ + EHRYYG S P  + S    E   YL V Q +AD A  +  +K    G S S VI  GGSY   +  W +  Y ++VAG  +SSAP L   N+    +I     +  +  G   C + I   I  +   I  + G A +  +  LC+P       DV TL S +++             A V     A  +   C++   G+ +D+  V     +  +  G      KC D             + N      W  QTC E  +          +  +  +T   +   C   YG       I  +++  N  F G+ F ++ N+  ++G LDPW A GI + +   I    I   AH  D       DT +++ +++     + +W+
Sbjct:   12 LALGQTHGSIFERTFKRIHEEPPLPTTQNRADVVQTLWIEQKLDHFD-PEETRTWQMRYMLNDALYQSGAPLFIYLGGEWEISSGRITGGHLYDMAKEHNALLAYTEHRYYGQSKPLPDLS---NENIKYLNVNQSLADLAYFINTIKQNHEGLSDSKVIIVGGSYSATMVTWFKKLYPDLVAGGWASSAPLLAKVNFVEYKEI---TGQSIEQMGGSACYKRIENGIAEMETMIATKRG-AEVKALLKLCEPFDVYSDLDVWTLFSEISDIF-----------AGVVQTHNAGQIEGVCEKIMAGS-NDLIGVAGYLLDVFEESG-----GKCYDLSYDAITALLLDTNYNGNIMRQWIFQTCNEYGWYQTSGSSAQPFGTKFPVT--YYTTMCADLYGSEYSNEFISNQVSITNQFFGGL-FPNVENVYLTHGQLDPWRAMGIQDETQATI----IPEHAHCKDFNSISSSDTAEMRASKERIAELVREWV 472          
BLAST of Lysosomal Pro-X carboxypeptidase vs. Ensembl Fly
Match: CG9953 (gene:FBgn0035726 transcript:FBtr0076898)

HSP 1 Score: 117.087 bits (292), Expect = 1.407e-27
Identity = 113/456 (24.78%), Postives = 189/456 (41.45%), Query Frame = 1
Query:  199 LTYETRYFQTYVDHFTFKNESLKFNLKYLISTKYW---SKGNVILFYCGN-EANIEFFARISGNLWELGEQLSALVVFAEHRYYGSSLPFGNKSFSSAEYFGYLTVEQVIADYATLLTYLKSKITGASKSPVIAFGGSYGGMLAAWLRLKYTNIVAGSISSSAPFLMVGNYKNCNKIFKVISKVYQSQGSKLCAENIRKIWPIIKA-INNRHGLAHLSKIFHLCQPLKD-VETLISFLNNALFEISVANFPYAASV---SVPLPAWPVREFCKRYTNGNLSDISNVLTSFYNAIQIYGNSTENSKCLDFQ-----------AADKNSFNSM-AWEIQTCMELPFPMCINGIHDIYFKENLITEGEFNNFCLKKYGIKPRLNWINILFS------GIHFQSLSNIIFSNGLLDPWSAGGILESSNKKIQLIKILNGAHHVDLRKSHPMDTTDIKMAR 1485
            L  E  +F+  +DHF   ++   +  +Y ++  ++   S   V L   G  EA+ ++     G      E   AL +  EHR+YG S P  + S    E   YL+ EQ + D A+ +T +K K         IAFGGSY G LAAW R KY  ++ GSISSS P L   ++K   ++ K     Y+ +    C + + + +  ++  + +  G   L + F  C P+KD +E  +   N   FE    NF         + P     + + C    N         L    + +    N+T    CLD++           + D  +   M  W  QTC E  F    +   D +   +      F   C+  +       ++ ++ S      G      +N+++ +G +DPW A G+++S+N  +  I I   AH  ++ +    D   +  AR
Sbjct:   52 LHSEDLWFEQRLDHFK-SSDKRTWQQRYFVNADFYRNDSSAPVFLMIGGEGEASAKWMRE--GAWVHYAEHFGALCLQLEHRFYGKSHPTADLS---TENLHYLSSEQALEDLASFVTAMKVKFNLGDGQKWIAFGGSYPGSLAAWAREKYPELIYGSISSSGPLLAEVDFKEYFEVVKASLAAYKPE----CVDAVTRSFAQVEILLKHMIGQRSLDEKFKTCTPIKDSIENDLDMAN--FFENLAGNFAGVVQYNKDNSPHATITIDDICDVMLNTTAGPPVTRLGLVNDMLLKESNTT----CLDYKYDKMVADMKNVSWDSETAKGMRQWTYQTCHEFGFYQTSDNPADTF--GDRFGVDFFIRQCMDVFSKNMNAKFLKLVVSATNDNYGALKPKTTNVLYVHGSIDPWHALGLVKSTNAALPTIYIEGTAHCANMYEPVKTDPPQLVAAR 489          
BLAST of Lysosomal Pro-X carboxypeptidase vs. Ensembl Zebrafish
Match: prcp (prolylcarboxypeptidase (angiotensinase C) [Source:ZFIN;Acc:ZDB-GENE-040718-447])

HSP 1 Score: 338.961 bits (868), Expect = 4.611e-110
Identity = 182/484 (37.60%), Postives = 280/484 (57.85%), Query Frame = 1
Query:   82 SCSFQMKLYLFLIQMHCLFLQQSFSYNKSKEIDKLSNYKLTYETRYFQTYVDHFTFKNESLKFNLKYLISTKYWSK-GNVILFYCGNEANIEFFARISGNLWELGEQLSALVVFAEHRYYGSSLPFGNKSFSSAEYFGYLTVEQVIADYATLLTYLKSKITGASKSPVIAFGGSYGGMLAAWLRLKYTNIVAGSISSSAPFLMVGNYKNCNKIFKVISKVYQSQGSKLCAENIRKIWPIIKAINNRHGLAHLSKIFHLCQPLKDVETLISF---LNNALFEISVANFPYAASVSVPLPAWPVREFCKRYT-NGNLSDISNVLTSFYNAIQIYGNSTENSKCLDFQAADKNSFNSMAWEIQTCMELPFPMCINGIHDIYFKENLITEGEFNNFCLKKYGIKPRLNWINILFSGIHFQSLSNIIFSNGLLDPWSAGGILESSNKKIQLIKILNGAHHVDLRKSHPMDTTDIKMARKLEKTTIEKWI 1518
            + SF++ + +F+     L L+  F   ++ +     +  ++Y T Y    +DHF F  E+  F  +YL++ ++W K G  ILFY GNE +I +F   +G +W++ E+L AL+VFAEHRYYG SLPFG +S+S+A+Y  YLT EQV+AD+A L+  LK    GA KS VIA GGSYGGMLAAWLR+KY N V G++++SAP         C + ++V+++ +   GS   +        I +      GL  LS+ F LC PLK  E +  F   L      +++ ++PY A    PLPAWPV+  CK    N  +SD   +L     A+++Y N T ++ CL+       +   + W  Q+C E+  PMC +GI+D+ F+    +   F++ C  ++G++PR +W   ++ G +  + SNIIFSNG LDPW +GG+ +S ++ +  I I  GAHH+DLR ++ +D   +  AR LE    ++WI
Sbjct:    7 ALSFRLLILIFIFSCKALALKPRF-LGRNTDQSFSQHRSVSYNTLYIDQQIDHFGFL-ENGTFKQRYLLNDQHWHKDGGPILFYTGNEGDITWFCNNTGFMWDVAEELGALLVFAEHRYYGESLPFGEESYSNAKYLNYLTSEQVLADFAVLIKALKKSQPGAEKSSVIAIGGSYGGMLAAWLRMKYPNAVVGALAASAPIWQF--IVPCGEFYRVVTRDFTISGSNCSSSIRSSWAAIDRLSATGEGLQWLSQTFGLCGPLKSQEDVFGFKAWLQETWVNLAMVDYPYEADFLQPLPAWPVKVVCKNLQFNKGVSD-KQLLNGVSQAVRVYYNYTGDAVCLNTSKTATGNLGFLGWFYQSCTEMVMPMCTDGINDM-FEPQPWSFQAFSDECYNQFGVRPREDWAETVYGGRNIHAHSNIIFSNGNLDPWMSGGVTKSLSESLLAIMIDGGAHHLDLRYNNELDPQSVIKARSLEVQYFKQWI 484          
BLAST of Lysosomal Pro-X carboxypeptidase vs. Ensembl Zebrafish
Match: dpp7 (dipeptidyl-peptidase 7 [Source:ZFIN;Acc:ZDB-GENE-050306-16])

HSP 1 Score: 304.294 bits (778), Expect = 1.152e-96
Identity = 169/467 (36.19%), Postives = 260/467 (55.67%), Query Frame = 1
Query:  160 NKSKEIDKLSNYKLTYETRYFQTYVDHFTFKN-ESLKFNLKYLISTKYWSKG-NVILFYCGNEANIEFFARISGNLWELGEQLSALVVFAEHRYYGSSLPFGNKSFSSAEYFGYLTVEQVIADYATLLTYLKSKITGASKSPVIAFGGSYGGMLAAWLRLKYTNIVAGSISSSAPFLMVGNYKNCNKIFKVISKVYQSQGSKLCAENIRKIWPIIKAINNRHGLAHLSKIFHLCQ---PLKDVETLISFLNNALFEISVANFPYAASVSVPLPAWPVREFCKRYTNGNLSDISNVLTSFYNAIQIYGNSTENSKCLDF-----QAADKNS----FNSMAWEIQTCMELPFPMCINGIHDIYFKENLITEGEFNNFCLKKYGIKPRLNWINILFSGIHFQSLSNIIFSNGLLDPWSAGGILESSNKKIQLIKILNGAHHVDLRKSHPMDTTDIKMARKLEKTTIEKWI 1518
            N S EI    +  L ++ +YF+  +DHF + +  +  ++ +YLI+ KYW KG   I FY GNE +I  FAR SG + EL     AL++FAEHRYYG SLPFG  SF   E  G LTVEQ +ADYA ++T LK ++ G    PVI FGGSYGGML+ ++R++Y NIVAG++++SAP L      +  + F+ ++  ++ + +  C   ++  +  +  +  +     +   F LC+     KD+  L  FL NA   +++ ++PY+      +PA+PV+  C+   NG     ++++++  + + I  N+T    C D      + AD       FNS AW+ Q C E+      N + D+ F     TE +   +C  ++G+ PR  W+   F G    + SNIIFSNG LDPW+ GGI +S +  +  I I  GAHH+DLR+S+P D   + +ARK E   I +W+
Sbjct:   26 NYSNEITSHRDLSLDFKEKYFKQILDHFNYNSLGNGTYDQRYLITDKYWKKGYGPIFFYTGNEGDISEFARNSGFMVELAAAQGALLIFAEHRYYGKSLPFGKNSFKIPE-VGLLTVEQALADYAVMITELKEEL-GGQTCPVIVFGGSYGGMLSVYMRIRYPNIVAGALAASAPILSTAGLGDPRQFFQDVTADFE-KFNPACRNAVQGAFQKLNTLAQQKDYIRIQSAFSLCKTPSSPKDIHQLNGFLRNAFTMMAMLDYPYSTHFMGSMPAFPVKVACEIMLNG-----TDLMSALRDTVGIVYNNTGELTCYDLYSLYVECADPTGCGLGFNSYAWDYQACTEIEMCFESNNVTDM-FPAMPFTEQQREQYCSNRWGVVPRPGWLKTQFWGNDLSTASNIIFSNGDLDPWANGGIRKSLSPSLIAITIPEGAHHLDLRESNPADPESVIVARKKEAEIIAQWV 483          
BLAST of Lysosomal Pro-X carboxypeptidase vs. Ensembl Zebrafish
Match: dpp7 (dipeptidyl-peptidase 7 [Source:ZFIN;Acc:ZDB-GENE-050306-16])

HSP 1 Score: 304.294 bits (778), Expect = 1.641e-96
Identity = 169/467 (36.19%), Postives = 260/467 (55.67%), Query Frame = 1
Query:  160 NKSKEIDKLSNYKLTYETRYFQTYVDHFTFKN-ESLKFNLKYLISTKYWSKG-NVILFYCGNEANIEFFARISGNLWELGEQLSALVVFAEHRYYGSSLPFGNKSFSSAEYFGYLTVEQVIADYATLLTYLKSKITGASKSPVIAFGGSYGGMLAAWLRLKYTNIVAGSISSSAPFLMVGNYKNCNKIFKVISKVYQSQGSKLCAENIRKIWPIIKAINNRHGLAHLSKIFHLCQ---PLKDVETLISFLNNALFEISVANFPYAASVSVPLPAWPVREFCKRYTNGNLSDISNVLTSFYNAIQIYGNSTENSKCLDF-----QAADKNS----FNSMAWEIQTCMELPFPMCINGIHDIYFKENLITEGEFNNFCLKKYGIKPRLNWINILFSGIHFQSLSNIIFSNGLLDPWSAGGILESSNKKIQLIKILNGAHHVDLRKSHPMDTTDIKMARKLEKTTIEKWI 1518
            N S EI    +  L ++ +YF+  +DHF + +  +  ++ +YLI+ KYW KG   I FY GNE +I  FAR SG + EL     AL++FAEHRYYG SLPFG  SF   E  G LTVEQ +ADYA ++T LK ++ G    PVI FGGSYGGML+ ++R++Y NIVAG++++SAP L      +  + F+ ++  ++ + +  C   ++  +  +  +  +     +   F LC+     KD+  L  FL NA   +++ ++PY+      +PA+PV+  C+   NG     ++++++  + + I  N+T    C D      + AD       FNS AW+ Q C E+      N + D+ F     TE +   +C  ++G+ PR  W+   F G    + SNIIFSNG LDPW+ GGI +S +  +  I I  GAHH+DLR+S+P D   + +ARK E   I +W+
Sbjct:   35 NYSNEITSHRDLSLDFKEKYFKQILDHFNYNSLGNGTYDQRYLITDKYWKKGYGPIFFYTGNEGDISEFARNSGFMVELAAAQGALLIFAEHRYYGKSLPFGKNSFKIPE-VGLLTVEQALADYAVMITELKEEL-GGQTCPVIVFGGSYGGMLSVYMRIRYPNIVAGALAASAPILSTAGLGDPRQFFQDVTADFE-KFNPACRNAVQGAFQKLNTLAQQKDYIRIQSAFSLCKTPSSPKDIHQLNGFLRNAFTMMAMLDYPYSTHFMGSMPAFPVKVACEIMLNG-----TDLMSALRDTVGIVYNNTGELTCYDLYSLYVECADPTGCGLGFNSYAWDYQACTEIEMCFESNNVTDM-FPAMPFTEQQREQYCSNRWGVVPRPGWLKTQFWGNDLSTASNIIFSNGDLDPWANGGIRKSLSPSLIAITIPEGAHHLDLRESNPADPESVIVARKKEAEIIAQWV 492          
BLAST of Lysosomal Pro-X carboxypeptidase vs. Ensembl Zebrafish
Match: dpp7 (dipeptidyl-peptidase 7 [Source:ZFIN;Acc:ZDB-GENE-050306-16])

HSP 1 Score: 304.294 bits (778), Expect = 1.641e-96
Identity = 169/467 (36.19%), Postives = 260/467 (55.67%), Query Frame = 1
Query:  160 NKSKEIDKLSNYKLTYETRYFQTYVDHFTFKN-ESLKFNLKYLISTKYWSKG-NVILFYCGNEANIEFFARISGNLWELGEQLSALVVFAEHRYYGSSLPFGNKSFSSAEYFGYLTVEQVIADYATLLTYLKSKITGASKSPVIAFGGSYGGMLAAWLRLKYTNIVAGSISSSAPFLMVGNYKNCNKIFKVISKVYQSQGSKLCAENIRKIWPIIKAINNRHGLAHLSKIFHLCQ---PLKDVETLISFLNNALFEISVANFPYAASVSVPLPAWPVREFCKRYTNGNLSDISNVLTSFYNAIQIYGNSTENSKCLDF-----QAADKNS----FNSMAWEIQTCMELPFPMCINGIHDIYFKENLITEGEFNNFCLKKYGIKPRLNWINILFSGIHFQSLSNIIFSNGLLDPWSAGGILESSNKKIQLIKILNGAHHVDLRKSHPMDTTDIKMARKLEKTTIEKWI 1518
            N S EI    +  L ++ +YF+  +DHF + +  +  ++ +YLI+ KYW KG   I FY GNE +I  FAR SG + EL     AL++FAEHRYYG SLPFG  SF   E  G LTVEQ +ADYA ++T LK ++ G    PVI FGGSYGGML+ ++R++Y NIVAG++++SAP L      +  + F+ ++  ++ + +  C   ++  +  +  +  +     +   F LC+     KD+  L  FL NA   +++ ++PY+      +PA+PV+  C+   NG     ++++++  + + I  N+T    C D      + AD       FNS AW+ Q C E+      N + D+ F     TE +   +C  ++G+ PR  W+   F G    + SNIIFSNG LDPW+ GGI +S +  +  I I  GAHH+DLR+S+P D   + +ARK E   I +W+
Sbjct:   35 NYSNEITSHRDLSLDFKEKYFKQILDHFNYNSLGNGTYDQRYLITDKYWKKGYGPIFFYTGNEGDISEFARNSGFMVELAAAQGALLIFAEHRYYGKSLPFGKNSFKIPE-VGLLTVEQALADYAVMITELKEEL-GGQTCPVIVFGGSYGGMLSVYMRIRYPNIVAGALAASAPILSTAGLGDPRQFFQDVTADFE-KFNPACRNAVQGAFQKLNTLAQQKDYIRIQSAFSLCKTPSSPKDIHQLNGFLRNAFTMMAMLDYPYSTHFMGSMPAFPVKVACEIMLNG-----TDLMSALRDTVGIVYNNTGELTCYDLYSLYVECADPTGCGLGFNSYAWDYQACTEIEMCFESNNVTDM-FPAMPFTEQQREQYCSNRWGVVPRPGWLKTQFWGNDLSTASNIIFSNGDLDPWANGGIRKSLSPSLIAITIPEGAHHLDLRESNPADPESVIVARKKEAEIIAQWV 492          
BLAST of Lysosomal Pro-X carboxypeptidase vs. Ensembl Zebrafish
Match: dpp7 (dipeptidyl-peptidase 7 [Source:ZFIN;Acc:ZDB-GENE-050306-16])

HSP 1 Score: 304.294 bits (778), Expect = 1.641e-96
Identity = 169/467 (36.19%), Postives = 260/467 (55.67%), Query Frame = 1
Query:  160 NKSKEIDKLSNYKLTYETRYFQTYVDHFTFKN-ESLKFNLKYLISTKYWSKG-NVILFYCGNEANIEFFARISGNLWELGEQLSALVVFAEHRYYGSSLPFGNKSFSSAEYFGYLTVEQVIADYATLLTYLKSKITGASKSPVIAFGGSYGGMLAAWLRLKYTNIVAGSISSSAPFLMVGNYKNCNKIFKVISKVYQSQGSKLCAENIRKIWPIIKAINNRHGLAHLSKIFHLCQ---PLKDVETLISFLNNALFEISVANFPYAASVSVPLPAWPVREFCKRYTNGNLSDISNVLTSFYNAIQIYGNSTENSKCLDF-----QAADKNS----FNSMAWEIQTCMELPFPMCINGIHDIYFKENLITEGEFNNFCLKKYGIKPRLNWINILFSGIHFQSLSNIIFSNGLLDPWSAGGILESSNKKIQLIKILNGAHHVDLRKSHPMDTTDIKMARKLEKTTIEKWI 1518
            N S EI    +  L ++ +YF+  +DHF + +  +  ++ +YLI+ KYW KG   I FY GNE +I  FAR SG + EL     AL++FAEHRYYG SLPFG  SF   E  G LTVEQ +ADYA ++T LK ++ G    PVI FGGSYGGML+ ++R++Y NIVAG++++SAP L      +  + F+ ++  ++ + +  C   ++  +  +  +  +     +   F LC+     KD+  L  FL NA   +++ ++PY+      +PA+PV+  C+   NG     ++++++  + + I  N+T    C D      + AD       FNS AW+ Q C E+      N + D+ F     TE +   +C  ++G+ PR  W+   F G    + SNIIFSNG LDPW+ GGI +S +  +  I I  GAHH+DLR+S+P D   + +ARK E   I +W+
Sbjct:   35 NYSNEITSHRDLSLDFKEKYFKQILDHFNYNSLGNGTYDQRYLITDKYWKKGYGPIFFYTGNEGDISEFARNSGFMVELAAAQGALLIFAEHRYYGKSLPFGKNSFKIPE-VGLLTVEQALADYAVMITELKEEL-GGQTCPVIVFGGSYGGMLSVYMRIRYPNIVAGALAASAPILSTAGLGDPRQFFQDVTADFE-KFNPACRNAVQGAFQKLNTLAQQKDYIRIQSAFSLCKTPSSPKDIHQLNGFLRNAFTMMAMLDYPYSTHFMGSMPAFPVKVACEIMLNG-----TDLMSALRDTVGIVYNNTGELTCYDLYSLYVECADPTGCGLGFNSYAWDYQACTEIEMCFESNNVTDM-FPAMPFTEQQREQYCSNRWGVVPRPGWLKTQFWGNDLSTASNIIFSNGDLDPWANGGIRKSLSPSLIAITIPEGAHHLDLRESNPADPESVIVARKKEAEIIAQWV 492          
BLAST of Lysosomal Pro-X carboxypeptidase vs. Ensembl Xenopus
Match: prcp (prolylcarboxypeptidase [Source:NCBI gene;Acc:780095])

HSP 1 Score: 381.333 bits (978), Expect = 2.202e-126
Identity = 192/485 (39.59%), Postives = 284/485 (58.56%), Query Frame = 1
Query:   85 CSFQMKLYLFLIQMHCLFLQQSFSYNKSKEIDKLSNYKLTYETRYFQTYVDHFTFKNESLKFNLKYLISTKYWSK-GNVILFYCGNEANIEFFARISGNLWELGEQLSALVVFAEHRYYGSSLPFGNKSFSSAEYFGYLTVEQVIADYATLLTYLKSKITGASKSPVIAFGGSYGGMLAAWLRLKYTNIVAGSISSSAPFLMVGNYKNCNKIFKVISKVYQSQGSKLCAENIRKIWPII-KAINNRHGLAHLSKIFHLCQPLK---DVETLISFLNNALFEISVANFPYAASVSVPLPAWPVREFCKRYTNGNLSDISNVLTSFYNAIQIYGNSTENSKCLDFQAADKNSFNSMAWEIQTCMELPFPMCINGIHDIYFKENLITEGEFNNFCLKKYGIKPRLNWINILFSGIHFQSLSNIIFSNGLLDPWSAGGILESSNKKIQLIKILNGAHHVDLRKSHPMDTTDIKMARKLEKTTIEKWISE 1524
            C+F     L L   H + L + F    S +    SN   +YET YF   VDHF F  E   F  +YL+S  YW K G  ILFY GNE +I  F   +G +W++ E++ A++VFAEHRYYG S+PFG+ +FS  ++  YLT EQ +AD+A LL Y K+   GA  SPVIA GGSYGGMLAAW R+KY ++V G+I+SSAP     +   CN+ ++V++  ++  G   C+E++R  W  I +      GL  LS  FHLC PLK   DV     +L+     +++ ++PY AS   PLPAWP++  CK   +    D  ++L   + A+ +Y N T ++ CL+       S   + W  Q C E+  P C +G+ D++  ++   +  F++ C K++G++PR +W+  ++ G +  S SNIIFSNG LDPWSAGG+ ES +  +  + I  GAHH+DLR ++  D   + +AR LE   ++KWI++
Sbjct:   13 CAFLAWNLLLLSAAHSVRLSRQFG---SAQQYGSSNPGPSYETYYFTQQVDHFGFY-EDATFKQRYLVSDTYWRKPGGPILFYTGNEGDITLFCNNTGFMWDVAEEMGAMLVFAEHRYYGESMPFGDLAFSDPKHLNYLTSEQALADFAVLLRYFKATTEGAQNSPVIALGGSYGGMLAAWFRMKYPDVVVGAIASSAPIWQFEDLVPCNEYYQVVTNDFKKSGPG-CSESVRNSWAAINRMAETTDGLQWLSNAFHLCCPLKSKEDVAVFKGWLSETWVSLAMVDYPYPASFLEPLPAWPIQVVCKFLKDPKSGD-KDLLQDIFQAVNVYYNYTGDTPCLNTSQTASGSLGDLGWSYQACTEMVMPFCSDGVSDMFEPQSWDLQA-FSDECYKQWGVRPRGSWVTTVYGGKNISSHSNIIFSNGGLDPWSAGGVKESLSDSLLAVLIPEGAHHLDLRSNNADDPKSVLLARSLEVEYMKKWIAQ 490          
BLAST of Lysosomal Pro-X carboxypeptidase vs. Ensembl Xenopus
Match: prcp (prolylcarboxypeptidase [Source:NCBI gene;Acc:780095])

HSP 1 Score: 366.696 bits (940), Expect = 3.369e-121
Identity = 177/436 (40.60%), Postives = 264/436 (60.55%), Query Frame = 1
Query:  232 VDHFTFKNESLKFNLKYLISTKYWSK-GNVILFYCGNEANIEFFARISGNLWELGEQLSALVVFAEHRYYGSSLPFGNKSFSSAEYFGYLTVEQVIADYATLLTYLKSKITGASKSPVIAFGGSYGGMLAAWLRLKYTNIVAGSISSSAPFLMVGNYKNCNKIFKVISKVYQSQGSKLCAENIRKIWPII-KAINNRHGLAHLSKIFHLCQPLK---DVETLISFLNNALFEISVANFPYAASVSVPLPAWPVREFCKRYTNGNLSDISNVLTSFYNAIQIYGNSTENSKCLDFQAADKNSFNSMAWEIQTCMELPFPMCINGIHDIYFKENLITEGEFNNFCLKKYGIKPRLNWINILFSGIHFQSLSNIIFSNGLLDPWSAGGILESSNKKIQLIKILNGAHHVDLRKSHPMDTTDIKMARKLEKTTIEKWISE 1524
            VDHF F  E   F  +YL+S  YW K G  ILFY GNE +I  F   +G +W++ E++ A++VFAEHRYYG S+PFG+ +FS  ++  YLT EQ +AD+A LL Y K+   GA  SPVIA GGSYGGMLAAW R+KY ++V G+I+SSAP     +   CN+ ++V++  ++  G   C+E++R  W  I +      GL  LS  FHLC PLK   DV     +L+     +++ ++PY AS   PLPAWP++  CK   +    D  ++L   + A+ +Y N T ++ CL+       S   + W  Q C E+  P C +G+ D++  ++   +  F++ C K++G++PR +W+  ++ G +  S SNIIFSNG LDPWSAGG+ ES +  +  + I  GAHH+DLR ++  D   + +AR LE   ++KWI++
Sbjct:   19 VDHFGFY-EDATFKQRYLVSDTYWRKPGGPILFYTGNEGDITLFCNNTGFMWDVAEEMGAMLVFAEHRYYGESMPFGDLAFSDPKHLNYLTSEQALADFAVLLRYFKATTEGAQNSPVIALGGSYGGMLAAWFRMKYPDVVVGAIASSAPIWQFEDLVPCNEYYQVVTNDFKKSGPG-CSESVRNSWAAINRMAETTDGLQWLSNAFHLCCPLKSKEDVAVFKGWLSETWVSLAMVDYPYPASFLEPLPAWPIQVVCKFLKDPKSGD-KDLLQDIFQAVNVYYNYTGDTPCLNTSQTASGSLGDLGWSYQACTEMVMPFCSDGVSDMFEPQSWDLQA-FSDECYKQWGVRPRGSWVTTVYGGKNISSHSNIIFSNGGLDPWSAGGVKESLSDSLLAVLIPEGAHHLDLRSNNADDPKSVLLARSLEVEYMKKWIAQ 450          
BLAST of Lysosomal Pro-X carboxypeptidase vs. Ensembl Xenopus
Match: prcp (prolylcarboxypeptidase [Source:NCBI gene;Acc:780095])

HSP 1 Score: 365.925 bits (938), Expect = 4.437e-121
Identity = 177/436 (40.60%), Postives = 264/436 (60.55%), Query Frame = 1
Query:  232 VDHFTFKNESLKFNLKYLISTKYWSK-GNVILFYCGNEANIEFFARISGNLWELGEQLSALVVFAEHRYYGSSLPFGNKSFSSAEYFGYLTVEQVIADYATLLTYLKSKITGASKSPVIAFGGSYGGMLAAWLRLKYTNIVAGSISSSAPFLMVGNYKNCNKIFKVISKVYQSQGSKLCAENIRKIWPII-KAINNRHGLAHLSKIFHLCQPLK---DVETLISFLNNALFEISVANFPYAASVSVPLPAWPVREFCKRYTNGNLSDISNVLTSFYNAIQIYGNSTENSKCLDFQAADKNSFNSMAWEIQTCMELPFPMCINGIHDIYFKENLITEGEFNNFCLKKYGIKPRLNWINILFSGIHFQSLSNIIFSNGLLDPWSAGGILESSNKKIQLIKILNGAHHVDLRKSHPMDTTDIKMARKLEKTTIEKWISE 1524
            VDHF F  E   F  +YL+S  YW K G  ILFY GNE +I  F   +G +W++ E++ A++VFAEHRYYG S+PFG+ +FS  ++  YLT EQ +AD+A LL Y K+   GA  SPVIA GGSYGGMLAAW R+KY ++V G+I+SSAP     +   CN+ ++V++  ++  G   C+E++R  W  I +      GL  LS  FHLC PLK   DV     +L+     +++ ++PY AS   PLPAWP++  CK   +    D  ++L   + A+ +Y N T ++ CL+       S   + W  Q C E+  P C +G+ D++  ++   +  F++ C K++G++PR +W+  ++ G +  S SNIIFSNG LDPWSAGG+ ES +  +  + I  GAHH+DLR ++  D   + +AR LE   ++KWI++
Sbjct:    5 VDHFGFY-EDATFKQRYLVSDTYWRKPGGPILFYTGNEGDITLFCNNTGFMWDVAEEMGAMLVFAEHRYYGESMPFGDLAFSDPKHLNYLTSEQALADFAVLLRYFKATTEGAQNSPVIALGGSYGGMLAAWFRMKYPDVVVGAIASSAPIWQFEDLVPCNEYYQVVTNDFKKSGPG-CSESVRNSWAAINRMAETTDGLQWLSNAFHLCCPLKSKEDVAVFKGWLSETWVSLAMVDYPYPASFLEPLPAWPIQVVCKFLKDPKSGD-KDLLQDIFQAVNVYYNYTGDTPCLNTSQTASGSLGDLGWSYQACTEMVMPFCSDGVSDMFEPQSWDLQA-FSDECYKQWGVRPRGSWVTTVYGGKNISSHSNIIFSNGGLDPWSAGGVKESLSDSLLAVLIPEGAHHLDLRSNNADDPKSVLLARSLEVEYMKKWIAD 436          
BLAST of Lysosomal Pro-X carboxypeptidase vs. Ensembl Xenopus
Match: prcp (prolylcarboxypeptidase [Source:NCBI gene;Acc:780095])

HSP 1 Score: 365.925 bits (938), Expect = 4.532e-121
Identity = 177/440 (40.23%), Postives = 266/440 (60.45%), Query Frame = 1
Query:  232 VDHFTFKNESLKFNLKYLISTKYWSK-GNVILFYCGNEANIEFFARISGNLWELGEQLSALVVFAEHRYYGSSLPFGNKSFSSAEYFGYLTVEQVIADYATLLTYLKSKITGASKSPVIAFGGSYGGMLAAWLRLKYTNIVAGSISSSAPFLMVGNYKNCNKIFKVISKVYQSQGSKLCAENIRKIWPII-KAINNRHGLAHLSKIFHLCQPLK---DVETLISFLNNALFEISVANFPYAASVSVPLPAWPVREFCKRYTNGNLSDISNVLTSFYNAIQIYGNSTENSKCLDFQAADKNSFNSMAWEIQTCMELPFPMCINGIHDIYFKENLITEGEFNNFCLKKYGIKPRLNWINILFSGIHFQSLSNIIFSNGLLDPWSAGGILESSNKKIQLIKILNGAHHVDLRKSHPMDTTDIKMARKLEKTTIEKWISEWHEQ 1536
            VDHF F  E   F  +YL+S  YW K G  ILFY GNE +I  F   +G +W++ E++ A++VFAEHRYYG S+PFG+ +FS  ++  YLT EQ +AD+A LL Y K+   GA  SPVIA GGSYGGMLAAW R+KY ++V G+I+SSAP     +   CN+ ++V++  ++  G   C+E++R  W  I +      GL  LS  FHLC PLK   DV     +L+     +++ ++PY AS   PLPAWP++  CK   +    D  ++L   + A+ +Y N T ++ CL+       S   + W  Q C E+  P C +G+ D++  ++   +  F++ C K++G++PR +W+  ++ G +  S SNIIFSNG LDPWSAGG+ ES +  +  + I  GAHH+DLR ++  D   + +AR LE   ++KWI+++  +
Sbjct:    5 VDHFGFY-EDATFKQRYLVSDTYWRKPGGPILFYTGNEGDITLFCNNTGFMWDVAEEMGAMLVFAEHRYYGESMPFGDLAFSDPKHLNYLTSEQALADFAVLLRYFKATTEGAQNSPVIALGGSYGGMLAAWFRMKYPDVVVGAIASSAPIWQFEDLVPCNEYYQVVTNDFKKSGPG-CSESVRNSWAAINRMAETTDGLQWLSNAFHLCCPLKSKEDVAVFKGWLSETWVSLAMVDYPYPASFLEPLPAWPIQVVCKFLKDPKSGD-KDLLQDIFQAVNVYYNYTGDTPCLNTSQTASGSLGDLGWSYQACTEMVMPFCSDGVSDMFEPQSWDLQA-FSDECYKQWGVRPRGSWVTTVYGGKNISSHSNIIFSNGGLDPWSAGGVKESLSDSLLAVLIPEGAHHLDLRSNNADDPKSVLLARSLEVEYMKKWIAQFERK 440          
BLAST of Lysosomal Pro-X carboxypeptidase vs. Ensembl Xenopus
Match: prcp (prolylcarboxypeptidase [Source:NCBI gene;Acc:780095])

HSP 1 Score: 366.311 bits (939), Expect = 5.899e-121
Identity = 177/436 (40.60%), Postives = 264/436 (60.55%), Query Frame = 1
Query:  232 VDHFTFKNESLKFNLKYLISTKYWSK-GNVILFYCGNEANIEFFARISGNLWELGEQLSALVVFAEHRYYGSSLPFGNKSFSSAEYFGYLTVEQVIADYATLLTYLKSKITGASKSPVIAFGGSYGGMLAAWLRLKYTNIVAGSISSSAPFLMVGNYKNCNKIFKVISKVYQSQGSKLCAENIRKIWPII-KAINNRHGLAHLSKIFHLCQPLK---DVETLISFLNNALFEISVANFPYAASVSVPLPAWPVREFCKRYTNGNLSDISNVLTSFYNAIQIYGNSTENSKCLDFQAADKNSFNSMAWEIQTCMELPFPMCINGIHDIYFKENLITEGEFNNFCLKKYGIKPRLNWINILFSGIHFQSLSNIIFSNGLLDPWSAGGILESSNKKIQLIKILNGAHHVDLRKSHPMDTTDIKMARKLEKTTIEKWISE 1524
            VDHF F  E   F  +YL+S  YW K G  ILFY GNE +I  F   +G +W++ E++ A++VFAEHRYYG S+PFG+ +FS  ++  YLT EQ +AD+A LL Y K+   GA  SPVIA GGSYGGMLAAW R+KY ++V G+I+SSAP     +   CN+ ++V++  ++  G   C+E++R  W  I +      GL  LS  FHLC PLK   DV     +L+     +++ ++PY AS   PLPAWP++  CK   +    D  ++L   + A+ +Y N T ++ CL+       S   + W  Q C E+  P C +G+ D++  ++   +  F++ C K++G++PR +W+  ++ G +  S SNIIFSNG LDPWSAGG+ ES +  +  + I  GAHH+DLR ++  D   + +AR LE   ++KWI++
Sbjct:   21 VDHFGFY-EDATFKQRYLVSDTYWRKPGGPILFYTGNEGDITLFCNNTGFMWDVAEEMGAMLVFAEHRYYGESMPFGDLAFSDPKHLNYLTSEQALADFAVLLRYFKATTEGAQNSPVIALGGSYGGMLAAWFRMKYPDVVVGAIASSAPIWQFEDLVPCNEYYQVVTNDFKKSGPG-CSESVRNSWAAINRMAETTDGLQWLSNAFHLCCPLKSKEDVAVFKGWLSETWVSLAMVDYPYPASFLEPLPAWPIQVVCKFLKDPKSGD-KDLLQDIFQAVNVYYNYTGDTPCLNTSQTASGSLGDLGWSYQACTEMVMPFCSDGVSDMFEPQSWDLQA-FSDECYKQWGVRPRGSWVTTVYGGKNISSHSNIIFSNGGLDPWSAGGVKESLSDSLLAVLIPEGAHHLDLRSNNADDPKSVLLARSLEVEYMKKWIAQ 452          
BLAST of Lysosomal Pro-X carboxypeptidase vs. Ensembl Mouse
Match: Prcp (prolylcarboxypeptidase (angiotensinase C) [Source:MGI Symbol;Acc:MGI:1919711])

HSP 1 Score: 371.318 bits (952), Expect = 1.248e-122
Identity = 179/449 (39.87%), Postives = 274/449 (61.02%), Query Frame = 1
Query:  205 YETRYFQTYVDHFTFKNESLKFNLKYLISTKYWSK-GNVILFYCGNEANIEFFARISGNLWELGEQLSALVVFAEHRYYGSSLPFGNKSFSSAEYFGYLTVEQVIADYATLLTYLKSKITGASKSPVIAFGGSYGGMLAAWLRLKYTNIVAGSISSSAPFLMVGNYKNCNKIFKVISKVYQSQGSKLCAENIRKIWPIIKAINNR-HGLAHLSKIFHLCQPL--KDVETLISFLNNALFEISVANFPYAASVSVPLPAWPVREFCKRYTNGNLSDISNVLTSFYNAIQIYGNSTENSKCLDFQAADKNSFNSMAWEIQTCMELPFPMCINGIHDIYFKENLITEGEFNNFCLKKYGIKPRLNWINILFSGIHFQSLSNIIFSNGLLDPWSAGGILESSNKKIQLIKILNGAHHVDLRKSHPMDTTDIKMARKLEKTTIEKWISEWHEQI 1539
            Y   YF+  VDHF F +    F  +YL++ K+W + G  ILFY GNE +I +F   +G +W++ E+L A++VFAEHRYYG SLPFG  SF  +++  +LT EQ +AD+A L+ +L+  I GA   PVIA GGSYGGMLAAW R+KY +IV G++++SAP   +     C +  K+++  ++  G   C+E+IRK W +I  ++    GL  L+ I HLC PL  + + TL  ++      +++ N+PYA +   PLPAWP++E C+   N N+SD + +L + + A+ +Y N +  + CL+      +S  SM W  Q C E+  P C NGI D+ F+  L    +++N C  ++G+KPR +W+  ++ G +  S SNIIFSNG LDPWS GG+       +  I I +GAHH+DLR  +  D + + ++R LE   ++KWI +++  I
Sbjct:   46 YSVLYFEQKVDHFGFADMR-TFKQRYLVADKHWQRNGGSILFYTGNEGDIVWFCNNTGFMWDVAEELKAMLVFAEHRYYGESLPFGQDSFKDSQHLNFLTSEQALADFAELIRHLEKTIPGAQGQPVIAIGGSYGGMLAAWFRMKYPHIVVGALAASAPIWQLDGMVPCGEFMKIVTNDFRKSG-PYCSESIRKSWNVIDKLSGSGSGLQSLTNILHLCSPLTSEKIPTLKGWIAETWVNLAMVNYPYACNFLQPLPAWPIKEVCQYLKNPNVSD-TVLLQNIFQALSVYYNYSGQAACLNISQTTTSSLGSMGWSFQACTEMVMPFCTNGIDDM-FEPFLWDLEKYSNDCFNQWGVKPRPHWMTTMYGGKNISSHSNIIFSNGELDPWSGGGVTRDITDTLVAINIHDGAHHLDLRAHNAFDPSSVLLSRLLEVKHMKKWILDFYSNI 490          
BLAST of Lysosomal Pro-X carboxypeptidase vs. Ensembl Mouse
Match: Prcp (prolylcarboxypeptidase (angiotensinase C) [Source:MGI Symbol;Acc:MGI:1919711])

HSP 1 Score: 341.658 bits (875), Expect = 1.328e-111
Identity = 172/448 (38.39%), Postives = 257/448 (57.37%), Query Frame = 1
Query:  205 YETRYFQTYVDHFTFKNESLKFNLKYLISTKYWSK-GNVILFYCGNEANIEFFARISGNLWELGEQLSALVVFAEHRYYGSSLPFGNKSFSSAEYFGYLTVEQVIADYATLLTYLKSKITGASKSPVIAFGGSYGGMLAAWLRLKYTNIVAGSISSSAPFLMVGNYKNCNKIFKVISKVYQSQGSKLCAENIRKIWPIIKAINNRHGLAHLSKIFHLCQPL--KDVETLISFLNNALFEISVANFPYAASVSVPLPAWPVREFCKRYTNGNLSDISNVLTSFYNAIQIYGNSTENSKCLDFQAADKNSFNSMAWEIQTCMELPFPMCINGIHDIYFKENLITEGEFNNFCLKKYGIKPRLNWINILFSGIHFQSLSNIIFSNGLLDPWSAGGILESSNKKIQLIKILNGAHHVDLRKSHPMDTTDIKMARKLEKTTIEKWISEWHEQI 1539
            Y   YF+  VDHF F +    F  +YL++ K+W + G  ILFY GNE +I +F   +G +W++ E+L A++VFAEHRYYG SLPFG  SF  +++  +LT EQ +AD+A L+ +L+  I GA   PVIA GGSYGGMLAAW R+KY +IV G++++SAP                   ++Q  G   C                  GL  L+ I HLC PL  + + TL  ++      +++ N+PYA +   PLPAWP++E C+   N N+SD + +L + + A+ +Y N +  + CL+      +S  SM W  Q C E+  P C NGI D+ F+  L    +++N C  ++G+KPR +W+  ++ G +  S SNIIFSNG LDPWS GG+       +  I I +GAHH+DLR  +  D + + ++R LE   ++KWI +++  I
Sbjct:   46 YSVLYFEQKVDHFGFADMR-TFKQRYLVADKHWQRNGGSILFYTGNEGDIVWFCNNTGFMWDVAEELKAMLVFAEHRYYGESLPFGQDSFKDSQHLNFLTSEQALADFAELIRHLEKTIPGAQGQPVIAIGGSYGGMLAAWFRMKYPHIVVGALAASAP-------------------IWQLDGMVPCGS----------------GLQSLTNILHLCSPLTSEKIPTLKGWIAETWVNLAMVNYPYACNFLQPLPAWPIKEVCQYLKNPNVSD-TVLLQNIFQALSVYYNYSGQAACLNISQTTTSSLGSMGWSFQACTEMVMPFCTNGIDDM-FEPFLWDLEKYSNDCFNQWGVKPRPHWMTTMYGGKNISSHSNIIFSNGELDPWSGGGVTRDITDTLVAINIHDGAHHLDLRAHNAFDPSSVLLSRLLEVKHMKKWILDFYSNI 455          
BLAST of Lysosomal Pro-X carboxypeptidase vs. Ensembl Mouse
Match: Dpp7 (dipeptidylpeptidase 7 [Source:MGI Symbol;Acc:MGI:1933213])

HSP 1 Score: 276.559 bits (706), Expect = 9.900e-86
Identity = 166/455 (36.48%), Postives = 249/455 (54.73%), Query Frame = 1
Query:  205 YETRYFQTYVDHFTFKNESLK-FNLKYLISTKYWSKG-NVILFYCGNEANIEFFARISGNLWELGEQLSALVVFAEHRYYGSSLPFGNKSFSSAEYFGYLTVEQVIADYATLLTYLKSKITGASKSPVIAFGGSYGGMLAAWLRLKYTNIVAGSISSSAPFLMVGNYKNCNKIFKVISKVYQSQGSKLCAENIRKIWPIIKAINNRHGLAHLSKIFHLCQPL---KDVETLISFLNNALFEISVANFPYAASVSVPLPAWPVREFCKRYTN-----------GNLSDISNVLTSFYNAIQIYGNSTENSKCLDFQAADKNSFNSMAWEIQTCMELPFPMCINGIHDIYFKENLITEGEFNNFCLKKYGIKPRLNWINILFSGIHFQSLSNIIFSNGLLDPWSAGGILESSNKKIQLIKILNGAHHVDLRKSHPMDTTDIKMARKLEKTTIEKWIS 1521
            +   YF+ Y+DHF F++   K F  ++L+S K+W  G   I FY GNE +I  FA  SG + EL  Q  AL+VFAEHRYYG SLPFG +S +   Y   LTVEQ +AD+A LL  L+  + G   +P IAFGGSYGGML+A++R+KY ++VAG++++SAP + V    +  + F+ ++  +  Q  K CA+ +R  +  IK +  +     +S+ F  CQ L   KD+  L  F  NA   +++ ++PY      PLPA PV+  C+R  N             L   S+     Y+  ++Y +  + + C           ++ AW+ Q C E+      N + D+ F E   +E     +CL  +G+ PR +W+   F G   ++ SNIIFSNG LDPW+ GGI  + +  +  + I  GAHH+DLR S+  D   +   RKLE T I +W++
Sbjct:   41 FHENYFEQYMDHFNFESFGNKTFGQRFLVSDKFWKMGEGPIFFYTGNEGDIWSFANNSGFMVELAAQQEALLVFAEHRYYGKSLPFGVQS-TQRGYTQLLTVEQALADFAVLLQALRQDL-GVHDAPTIAFGGSYGGMLSAYMRMKYPHLVAGALAASAPVVAVAGLGDSYQFFRDVTADFYGQSPK-CAQAVRDAFQQIKDLFLQGAYDTISQNFGTCQSLSSPKDLTQLFGFARNAFTVLAMMDYPYPTDFLGPLPANPVKVGCQRLLNEGQRIMGLRALAGLVYNSSGTEPCYDIYRLYQSCADPTGC-------GTGSDARAWDYQACTEINLTFDSNNVTDM-FPEIPFSEELRQQYCLDTWGVWPRQDWLQTSFWGGDLKAASNIIFSNGDLDPWAGGGIQSNLSTSVIAVTIQGGAHHLDLRASNSEDPPSVVEVRKLESTLIREWVA 484          
BLAST of Lysosomal Pro-X carboxypeptidase vs. Ensembl Mouse
Match: Prss16 (protease, serine 16 (thymus) [Source:MGI Symbol;Acc:MGI:1859181])

HSP 1 Score: 114.775 bits (286), Expect = 1.082e-26
Identity = 108/466 (23.18%), Postives = 185/466 (39.70%), Query Frame = 1
Query:  217 YFQTYVDHFTFKNESLKFNLKYLISTKYWSKGNVILF-YCGNEANIEFFARISGNLWELGEQLSALVVFAEHRYYGSSLPFGNKSFSSAEYFGYLTVEQVIADYATLLTYLKSKITGASKSPVIAFGGSYGGMLAAWLRLKYTNIVAGSISSSAPFLMVGNYKNCNKIFKVISKVYQSQGSKLC----------AENIRKIWPIIKAINNRHGLAHLSKIFHLCQPLKDVETLISFLNNALFEISVANFPYAASVSVPLPAWPVREFCKRYTN--GNLSDISNVLTSFYNAIQIYGNSTENSKCLDFQAADK-----------NSFNSMAWEIQTCMELPFPMCINGIHDIYFKENLITEGEFN-NFCLKKYGIKP-----RLNWINILFSGIHFQSLSNIIFSNGLLDPWSAGGILESSNKKIQLIKILNGAHHVDLRKSHPMDTTDIKMARKLEKTTIEKWISE 1524
            + +  +D F   +    F  +Y ++ ++ +  +V +F + G E ++   + ++G+   L     ALV+  EHR+YG S+P G    +      YL+    +AD A+    L   +  +S SP I FGGSY G LA W RLK+ ++V  +++SSAP   V ++   N++           GS  C           E + +  P  +A+        L +    C  L   E     L  AL  +      Y      PL    VR+ C       GN S  +  L     A+QI   S    KCL F  A+            +      W  QTC E  F +   G+   + +   +    F    C + +G+ P      +   N  + G      + ++F NG  DPW    + +        + I + +H  D+    P D+  +++ R+     ++ W+ +
Sbjct:   60 WLEQPLDPFNASDRR-TFLQRYWVNDQHRTGQDVPVFLHIGGEGSLGPGSVMAGHPAALAPAWGALVISLEHRFYGLSMPAGGLDLA---LLRYLSSRHALADVASARQALSGLLNVSSSSPWICFGGSYAGSLATWARLKFPHLVFAAVASSAPLSAVVDFSAYNQVVARSLTQVAIGGSLECLAAASTAFTEVERLLRAGPAAQAV--------LREELGACGSLDLTEDQAELL-GALQALVGGTVQYDGQAGAPL---SVRQLCGLLLGKWGNRSRSTPYL-GLRRAVQIVLRSM-GQKCLSFSRAETVAQLSNTEPQVSGVGDRQWLYQTCTEFGFYVTCEGLQCPFSQLPAL---PFQLELCEQVFGLSPASVAQAVAQTNSYYGG-QSPGATQVLFVNGDTDPWHVLSVTQDLGLSEPALLIPSASHCFDMAPMRPSDSPSLRLGRQKISQQLQDWLKD 503          
BLAST of Lysosomal Pro-X carboxypeptidase vs. UniProt/SwissProt
Match: sp|Q7TMR0|PCP_MOUSE (Lysosomal Pro-X carboxypeptidase OS=Mus musculus OX=10090 GN=Prcp PE=1 SV=2)

HSP 1 Score: 371.318 bits (952), Expect = 8.728e-122
Identity = 179/449 (39.87%), Postives = 274/449 (61.02%), Query Frame = 1
Query:  205 YETRYFQTYVDHFTFKNESLKFNLKYLISTKYWSK-GNVILFYCGNEANIEFFARISGNLWELGEQLSALVVFAEHRYYGSSLPFGNKSFSSAEYFGYLTVEQVIADYATLLTYLKSKITGASKSPVIAFGGSYGGMLAAWLRLKYTNIVAGSISSSAPFLMVGNYKNCNKIFKVISKVYQSQGSKLCAENIRKIWPIIKAINNR-HGLAHLSKIFHLCQPL--KDVETLISFLNNALFEISVANFPYAASVSVPLPAWPVREFCKRYTNGNLSDISNVLTSFYNAIQIYGNSTENSKCLDFQAADKNSFNSMAWEIQTCMELPFPMCINGIHDIYFKENLITEGEFNNFCLKKYGIKPRLNWINILFSGIHFQSLSNIIFSNGLLDPWSAGGILESSNKKIQLIKILNGAHHVDLRKSHPMDTTDIKMARKLEKTTIEKWISEWHEQI 1539
            Y   YF+  VDHF F +    F  +YL++ K+W + G  ILFY GNE +I +F   +G +W++ E+L A++VFAEHRYYG SLPFG  SF  +++  +LT EQ +AD+A L+ +L+  I GA   PVIA GGSYGGMLAAW R+KY +IV G++++SAP   +     C +  K+++  ++  G   C+E+IRK W +I  ++    GL  L+ I HLC PL  + + TL  ++      +++ N+PYA +   PLPAWP++E C+   N N+SD + +L + + A+ +Y N +  + CL+      +S  SM W  Q C E+  P C NGI D+ F+  L    +++N C  ++G+KPR +W+  ++ G +  S SNIIFSNG LDPWS GG+       +  I I +GAHH+DLR  +  D + + ++R LE   ++KWI +++  I
Sbjct:   46 YSVLYFEQKVDHFGFADMR-TFKQRYLVADKHWQRNGGSILFYTGNEGDIVWFCNNTGFMWDVAEELKAMLVFAEHRYYGESLPFGQDSFKDSQHLNFLTSEQALADFAELIRHLEKTIPGAQGQPVIAIGGSYGGMLAAWFRMKYPHIVVGALAASAPIWQLDGMVPCGEFMKIVTNDFRKSG-PYCSESIRKSWNVIDKLSGSGSGLQSLTNILHLCSPLTSEKIPTLKGWIAETWVNLAMVNYPYACNFLQPLPAWPIKEVCQYLKNPNVSD-TVLLQNIFQALSVYYNYSGQAACLNISQTTTSSLGSMGWSFQACTEMVMPFCTNGIDDM-FEPFLWDLEKYSNDCFNQWGVKPRPHWMTTMYGGKNISSHSNIIFSNGELDPWSGGGVTRDITDTLVAINIHDGAHHLDLRAHNAFDPSSVLLSRLLEVKHMKKWILDFYSNI 490          
BLAST of Lysosomal Pro-X carboxypeptidase vs. UniProt/SwissProt
Match: sp|Q5RBU7|PCP_PONAB (Lysosomal Pro-X carboxypeptidase OS=Pongo abelii OX=9601 GN=PRCP PE=2 SV=1)

HSP 1 Score: 371.318 bits (952), Expect = 1.280e-121
Identity = 176/451 (39.02%), Postives = 276/451 (61.20%), Query Frame = 1
Query:  205 YETRYFQTYVDHFTFKNESLKFNLKYLISTKYWSK-GNVILFYCGNEANIEFFARISGNLWELGEQLSALVVFAEHRYYGSSLPFGNKSFSSAEYFGYLTVEQVIADYATLLTYLKSKITGASKSPVIAFGGSYGGMLAAWLRLKYTNIVAGSISSSAPFLMVGNYKNCNKIFKVISKVYQSQGSKLCAENIRKIWPIIKAINNR-HGLAHLSKIFHLCQPL--KDVETLISFLNNALFEISVANFPYAASVSVPLPAWPVREFCKRYTNGNLSDISNVLTSFYNAIQIYGNSTENSKCLDFQAADKNSFNSMAWEIQTCMELPFPMCINGIHDIYFKENLITEGEFNNFCLKKYGIKPRLNWINILFSGIHFQSLSNIIFSNGLLDPWSAGGILESSNKKIQLIKILNGAHHVDLRKSHPMDTTDIKMARKLEKTTIEKWISEWHEQIAK 1545
            Y   YFQ  VDHF F N    FN +YL++ KYW K G  ILFY GNE +I +F   +G +W++ E+L A++VFAEHRYYG SLPFG+ +F  + +  +LT EQ +AD+A L+ +LK  I GA   PVIA GGSYGGMLAAW R+KY ++V G++++SAP     +   C    K+++  ++  G   C+E+IR+ W  I  ++N   GL  L+   HLC PL  +D++ L  +++     +++ ++PYA++   PLPAWP++  C+   N N+SD S +L + + A+ +Y N +   KCL+      +S  ++ W  Q C E+  P C NG+ D+ F+ +     E ++ C +++G++PR +WI  ++ G +  S +NI+FSNG LDPWS GG+ +     +  + I  GAHH+DLR  + +D T + +AR LE   ++ WI ++++   K
Sbjct:   48 YSVLYFQQKVDHFGF-NTVKTFNQRYLVADKYWKKNGGSILFYTGNEGDIIWFCNNTGFMWDVAEELKAMLVFAEHRYYGESLPFGDNTFKDSRHLNFLTSEQALADFAELIKHLKRTIPGAENQPVIAIGGSYGGMLAAWFRMKYPHMVVGALAASAPIWQFEDLVPCGVFMKIVTTDFRKSGPH-CSESIRRSWDAINRLSNTGSGLQWLTGALHLCSPLTSQDIQHLKDWISETWVNLAMVDYPYASNFLQPLPAWPIKVVCQYLKNPNVSD-SLLLQNIFQALNVYYNYSGQVKCLNISETATSSLGTLGWSYQACTEVVMPFCTNGVDDM-FEPHSWNLKELSDDCFQQWGVRPRPSWITTMYGGKNISSHTNIVFSNGELDPWSGGGVTKDITDTLVAVTISEGAHHLDLRTKNALDPTSVLLARSLEVRHMKNWIRDFYDSAGK 494          
BLAST of Lysosomal Pro-X carboxypeptidase vs. UniProt/SwissProt
Match: sp|Q2TA14|PCP_BOVIN (Lysosomal Pro-X carboxypeptidase OS=Bos taurus OX=9913 GN=PRCP PE=2 SV=1)

HSP 1 Score: 368.622 bits (945), Expect = 1.540e-120
Identity = 178/455 (39.12%), Postives = 279/455 (61.32%), Query Frame = 1
Query:  199 LTYETRYFQTYVDHFTFKNESLKFNLKYLISTKYWSK-GNVILFYCGNEANIEFFARISGNLWELGEQLSALVVFAEHRYYGSSLPFGNKSFSSAEYFGYLTVEQVIADYATLLTYLKSKITGASKSPVIAFGGSYGGMLAAWLRLKYTNIVAGSISSSAPFLMVGNYKNCNKIFKVISKVYQSQGSKLCAENIRKIWPIIKAINNR-HGLAHLSKIFHLCQPL---KDVETLISFLNNALFEISVANFPYAASVSVPLPAWPVREFCKRYTNGNLSDISNVLTSFYNAIQIYGNSTENSKCLDFQAADKNSFNSMAWEIQTCMELPFPMCINGIHDIYFKENLITEGEFNNFCLKKYGIKPRLNWINILFSGIHFQSLSNIIFSNGLLDPWSAGGILESSNKKIQLIKILNGAHHVDLRKSHPMDTTDIKMARKLEKTTIEKWISEWHEQIAKI 1548
            L Y  RY Q  VDHF F N    F  +YLI+  YW + G  ILFY GNE +I +F   +G +W++ E++ A++VFAEHRYYG SLPFG  SFS + +  +LT EQ +AD+A L+ YLK  I GA    VIA GGSYGGMLAAW R+KY ++V G+++SSAP     +   C+   K+++  + SQ    C+E+IR+ W  I  +  +  GL  LS+  HLC PL   +DV+ L  +++     +++ ++PY ++   PLPAWPV+  C+ +   N+ D + ++ + + A+ +Y N +  +KCL+      +S   + W  Q C E+  P C +G+ D+ F+ +     E+++ C K++G++PR +WI  ++ G +  S +NIIFSNG LDPWS GG+ +     +  I I NGAHH+DLR S+ +D   +++ R LE   +++WIS+++ ++ K+
Sbjct:   48 LKYSIRYIQQKVDHFGF-NIDRTFKQRYLIADNYWKEDGGSILFYTGNEGDIIWFCNNTGFMWDIAEEMKAMLVFAEHRYYGESLPFGADSFSDSRHLNFLTTEQALADFAKLIRYLKRTIPGARNQHVIALGGSYGGMLAAWFRMKYPHLVVGALASSAPIWQFNDLVPCDIFMKIVTTDF-SQSGPNCSESIRRSWDAINRLAKKGTGLRWLSEALHLCTPLTKSQDVQRLKDWISETWVNVAMVDYPYESNFLQPLPAWPVKVVCQYFKYSNVPD-TVMVQNIFQALNVYYNYSGQAKCLNVSETATSSLGVLGWSYQACTEMVMPTCSDGVDDM-FEPHSWNMKEYSDDCFKQWGVRPRPSWIPTMYGGKNISSHTNIIFSNGELDPWSGGGVTKDITDTLLAIVIPNGAHHLDLRASNALDPVSVQLTRSLEVKYMKQWISDFYVRLRKM 498          
BLAST of Lysosomal Pro-X carboxypeptidase vs. UniProt/SwissProt
Match: sp|P42785|PCP_HUMAN (Lysosomal Pro-X carboxypeptidase OS=Homo sapiens OX=9606 GN=PRCP PE=1 SV=1)

HSP 1 Score: 367.466 bits (942), Expect = 3.702e-120
Identity = 175/451 (38.80%), Postives = 274/451 (60.75%), Query Frame = 1
Query:  205 YETRYFQTYVDHFTFKNESLKFNLKYLISTKYWSK-GNVILFYCGNEANIEFFARISGNLWELGEQLSALVVFAEHRYYGSSLPFGNKSFSSAEYFGYLTVEQVIADYATLLTYLKSKITGASKSPVIAFGGSYGGMLAAWLRLKYTNIVAGSISSSAPFLMVGNYKNCNKIFKVISKVYQSQGSKLCAENIRKIWPIIKAINNR-HGLAHLSKIFHLCQPL--KDVETLISFLNNALFEISVANFPYAASVSVPLPAWPVREFCKRYTNGNLSDISNVLTSFYNAIQIYGNSTENSKCLDFQAADKNSFNSMAWEIQTCMELPFPMCINGIHDIYFKENLITEGEFNNFCLKKYGIKPRLNWINILFSGIHFQSLSNIIFSNGLLDPWSAGGILESSNKKIQLIKILNGAHHVDLRKSHPMDTTDIKMARKLEKTTIEKWISEWHEQIAK 1545
            Y   YFQ  VDHF F N    FN +YL++ KYW K G  ILFY GNE +I +F   +G +W++ E+L A++VFAEHRYYG SLPFG+ SF  + +  +LT EQ +AD+A L+ +LK  I GA   PVIA GGSYGGMLAAW R+KY ++V G++++SAP     +   C    K+++  ++  G   C+E+I + W  I  ++N   GL  L+   HLC PL  +D++ L  +++     +++ ++PYA++   PLPAWP++  C+   N N+SD S +L + + A+ +Y N +   KCL+      +S  ++ W  Q C E+  P C NG+ D+ F+ +     E ++ C +++G++PR +WI  ++ G +  S +NI+FSNG LDPWS GG+ +     +  + I  GAHH+DLR  + +D   + +AR LE   ++ WI ++++   K
Sbjct:   48 YSVLYFQQKVDHFGF-NTVKTFNQRYLVADKYWKKNGGSILFYTGNEGDIIWFCNNTGFMWDVAEELKAMLVFAEHRYYGESLPFGDNSFKDSRHLNFLTSEQALADFAELIKHLKRTIPGAENQPVIAIGGSYGGMLAAWFRMKYPHMVVGALAASAPIWQFEDLVPCGVFMKIVTTDFRKSGPH-CSESIHRSWDAINRLSNTGSGLQWLTGALHLCSPLTSQDIQHLKDWISETWVNLAMVDYPYASNFLQPLPAWPIKVVCQYLKNPNVSD-SLLLQNIFQALNVYYNYSGQVKCLNISETATSSLGTLGWSYQACTEVVMPFCTNGVDDM-FEPHSWNLKELSDDCFQQWGVRPRPSWITTMYGGKNISSHTNIVFSNGELDPWSGGGVTKDITDTLVAVTISEGAHHLDLRTKNALDPMSVLLARSLEVRHMKNWIRDFYDSAGK 494          
BLAST of Lysosomal Pro-X carboxypeptidase vs. UniProt/SwissProt
Match: sp|Q9UHL4|DPP2_HUMAN (Dipeptidyl peptidase 2 OS=Homo sapiens OX=9606 GN=DPP7 PE=1 SV=3)

HSP 1 Score: 298.13 bits (762), Expect = 2.192e-93
Identity = 169/452 (37.39%), Postives = 253/452 (55.97%), Query Frame = 1
Query:  205 YETRYFQTYVDHFTFKNESLK-FNLKYLISTKYWSKG-NVILFYCGNEANIEFFARISGNLWELGEQLSALVVFAEHRYYGSSLPFGNKSFSSAEYFGYLTVEQVIADYATLLTYLKSKITGASKSPVIAFGGSYGGMLAAWLRLKYTNIVAGSISSSAPFLMVGNYKNCNKIFKVISKVYQSQGSKLCAENIRKIWPIIKAINNRHGLAHLSKIFHLCQPL---KDVETLISFLNNALFEISVANFPYAASVSVPLPAWPVREFCKRYTNGNLSDISNVLTSFYNAIQIYGNSTENSKCLDF-----QAADKNSF----NSMAWEIQTCMELPFPMCINGIHDIYFKENLITEGEFNNFCLKKYGIKPRLNWINILFSGIHFQSLSNIIFSNGLLDPWSAGGILESSNKKIQLIKILNGAHHVDLRKSHPMDTTDIKMARKLEKTTIEKWI 1518
            ++ R+FQ  +DHF F+    K F  ++L+S ++W +G   I FY GNE ++  FA  S  + EL  +  AL+VFAEHRYYG SLPFG +S +   +   LTVEQ +AD+A LL  L+  + GA  +P IAFGGSYGGML+A+LR+KY ++VAG++++SAP L V    + N+ F+ ++  ++ Q  K C + +R+ +  IK +  +     +   F  CQPL   KD+  L  F  NA   +++ ++PY      PLPA PV+  C R     LS+   +      A  +Y N++ +  C D        AD        ++ AW+ Q C E+      N + D+ F +   T+     +CL  +G+ PR +W+   F G   ++ SNIIFSNG LDPW+ GGI  + +  +  + I  GAHH+DLR SHP D   +  ARKLE T I +W+
Sbjct:   31 FQERFFQQRLDHFNFERFGNKTFPQRFLVSDRFWVRGEGPIFFYTGNEGDVWAFANNSAFVAELAAERGALLVFAEHRYYGKSLPFGAQS-TQRGHTELLTVEQALADFAELLRALRRDL-GAQDAPAIAFGGSYGGMLSAYLRMKYPHLVAGALAASAPVLAVAGLGDSNQFFRDVTADFEGQSPK-CTQGVREAFRQIKDLFLQGAYDTVRWEFGTCQPLSDEKDLTQLFMFARNAFTVLAMMDYPYPTDFLGPLPANPVKVGCDRL----LSEAQRITGLRALAGLVY-NASGSEHCYDIYRLYHSCADPTGCGTGPDARAWDYQACTEINLTFASNNVTDM-FPDLPFTDELRQRYCLDTWGVWPRPDWLLTSFWGGDLRAASNIIFSNGNLDPWAGGGIRRNLSASVIAVTIQGGAHHLDLRASHPEDPASVVEARKLEATIIGEWV 473          
BLAST of Lysosomal Pro-X carboxypeptidase vs. TrEMBL
Match: A0A0X3PYJ7 (Uncharacterized protein OS=Schistocephalus solidus OX=70667 GN=TR147549 PE=4 SV=1)

HSP 1 Score: 396.356 bits (1017), Expect = 5.320e-129
Identity = 194/436 (44.50%), Postives = 265/436 (60.78%), Query Frame = 1
Query:  232 VDHFTFKNESLKFNLKYLISTKYWSKGNVILFYCGNEANIEFFARISGNLWELGEQLSALVVFAEHRYYGSSLPFGNKSFSSAEYFGYLTVEQVIADYATLLTYLKSKITGASKSPVIAFGGSYGGMLAAWLRLKYTNIVAGSISSSAPFLMVGNYKNCNKIFKVISKVYQSQGSKLCAENIRKIWPIIKAINNR-HGLAHLSKIFHLCQPLKDVETLISFLNNALFEISVANFPYAASVSVPLPAWPVREFCKRYTNGNLSD-ISNVLTSFYNAIQIYGNSTENSKCLDFQAADKNSFNSMAWEIQTCMELPFPMCINGIHDIYFKENLITEGEFNNFCLKKYGIKPRLNWINILFSGIHFQSLSNIIFSNGLLDPWSAGGILESSNKK-IQLIKILNGAHHVDLRKSHPMDTTDIKMARKLEKTTIEKWISEWH 1530
            VDHF+F  + + +N+ YL+    +     I FY GNE  IE FA  SG ++EL   LSA+V+FAEHRYYGSSLPFGN SFS  ++FGYLT EQ +ADYA  LT  K      +  PVI+FGGSYGGML AW R KY NI+AG +++SAP  +      CN   +V ++ Y   G   C + +R  WP++  I +   GL  LS++F  C P+ +   L  F  + L  +++AN+PY +S   PLPAWPV EFCK       S  + + +  F  A+    N     +CL    AD  + ++  WE+QTC+E+P P+C NG  D+ FK  +     F++ C   +G++PR+NW ++ F G +  SL+N+IFSNG LDPWSA G+LE S    + +I+I  GAHH+DLR SHP DT ++K AR  EK  IEKWI EWH
Sbjct:   43 VDHFSFAKKDI-YNMTYLLYRNNFEHATSIFFYTGNEGRIEHFAENSGFIFELAASLSAVVIFAEHRYYGSSLPFGNGSFSDRKHFGYLTAEQALADYAEFLTEFKCANPELADLPVISFGGSYGGMLTAWFRQKYPNIIAGGLAASAPVWLFPGMAECNGFLRVTTETYDRAGGTACVDMVRMTWPLVDQIGSTPEGLEDLSRVFKSCTPIPNATFLYDFAQDFLITLAMANYPYESSFLGPLPAWPVTEFCKALETCRPSGLLPDPVEKFACALFSLANYNRTDECLSLN-ADAENIDAHGWELQTCLEMPTPVCANGETDM-FKPQVWDPLAFSDHCENTFGVRPRMNWADVNFWGRNLHSLTNVIFSNGDLDPWSALGVLEGSQAPNVDIIRIATGAHHLDLRGSHPNDTVEVKYARAQEKDIIEKWIREWH 475          
BLAST of Lysosomal Pro-X carboxypeptidase vs. TrEMBL
Match: A0A1D5PVG8 (Prolylcarboxypeptidase OS=Gallus gallus OX=9031 GN=PRCP PE=4 SV=1)

HSP 1 Score: 394.045 bits (1011), Expect = 3.463e-128
Identity = 191/449 (42.54%), Postives = 282/449 (62.81%), Query Frame = 1
Query:  205 YETRYFQTYVDHFTFKNESLKFNLKYLISTKYWSKGN-VILFYCGNEANIEFFARISGNLWELGEQLSALVVFAEHRYYGSSLPFGNKSFSSAEYFGYLTVEQVIADYATLLTYLKSKITGASKSPVIAFGGSYGGMLAAWLRLKYTNIVAGSISSSAPFLMVGNYKNCNKIFKVISKVYQSQGSKLCAENIRKIWPIIKAINNRH-GLAHLSKIFHLCQPLK---DVETLISFLNNALFEISVANFPYAASVSVPLPAWPVREFCKRYTNGNLSDISNVLTSFYNAIQIYGNSTENSKCLDFQAADKNSFNSMAWEIQTCMELPFPMCINGIHDIYFKENLITEGEFNNFCLKKYGIKPRLNWINILFSGIHFQSLSNIIFSNGLLDPWSAGGILESSNKKIQLIKILNGAHHVDLRKSHPMDTTDIKMARKLEKTTIEKWISEWHEQ 1536
            Y TRY    +DHF F +E+L F  +YLI+ ++W K N  ILFY GNE +I +F   +G +W++ E+L+A++VFAEHRYYG SLPFGN+SFS +++  YLT EQ +AD+A L+ YLK  I GA  SPVIA GGSYGGMLAAW R+KY ++V G++++SAP    G+   C   F +++  ++  G+  C+E+IR  W  I  +++   GL  LS+ FHLC PLK   D   L ++L+    ++++ ++PY A    PLPAWP+RE CK   + +LSD   +L + + AI IY N T  + C D       +   + W  Q C E+  PMC +G+HD++  +    E   ++ C + +G++PR +WI  ++ G +  S SNIIFSNG LDPWSAGG+ ++    +  I I +GAHH+DLR  +P D   ++ AR LE   +++WI+E   Q
Sbjct:   38 YLTRYLTQQIDHFGF-DENLTFQQRYLIADQHWKKDNGPILFYTGNEGDITWFCNNTGFMWDVAEELNAMLVFAEHRYYGESLPFGNESFSDSKHLNYLTSEQALADFAVLIEYLKETIAGARHSPVIAIGGSYGGMLAAWFRMKYPHVVVGALAASAPIWQFGDLVPCGAYFTIVTNDFKKSGTG-CSESIRNSWNAINHLSSTDVGLQWLSRTFHLCSPLKNLQDAAMLKTWLSETWIDLAMVDYPYKADFLQPLPAWPIREVCKFLKDPSLSD-KLLLQNIFQAINIYYNYTGEASCFDMSETATKNLGQLGWYYQVCTEMVMPMCTDGVHDMFEPQKWDFEA-LSDECFRLWGVRPRPSWILSMYGGKNISSHSNIIFSNGGLDPWSAGGVTQNVTDSLVAIVIPDGAHHLDLRSRNPCDPKSVQQARALEVHYMKQWIAEAKHQ 482          
BLAST of Lysosomal Pro-X carboxypeptidase vs. TrEMBL
Match: U3JZA6 (Prolylcarboxypeptidase OS=Ficedula albicollis OX=59894 GN=PRCP PE=4 SV=1)

HSP 1 Score: 390.193 bits (1001), Expect = 4.766e-127
Identity = 186/445 (41.80%), Postives = 280/445 (62.92%), Query Frame = 1
Query:  205 YETRYFQTYVDHFTFKNESLKFNLKYLISTKYWSKGN-VILFYCGNEANIEFFARISGNLWELGEQLSALVVFAEHRYYGSSLPFGNKSFSSAEYFGYLTVEQVIADYATLLTYLKSKITGASKSPVIAFGGSYGGMLAAWLRLKYTNIVAGSISSSAPFLMVGNYKNCNKIFKVISKVYQSQGSKLCAENIRKIWPIIKAINNRH-GLAHLSKIFHLCQPLK---DVETLISFLNNALFEISVANFPYAASVSVPLPAWPVREFCKRYTNGNLSDISNVLTSFYNAIQIYGNSTENSKCLDFQAADKNSFNSMAWEIQTCMELPFPMCINGIHDIYFKENLITEGEFNNFCLKKYGIKPRLNWINILFSGIHFQSLSNIIFSNGLLDPWSAGGILESSNKKIQLIKILNGAHHVDLRKSHPMDTTDIKMARKLEKTTIEKWISE 1524
            Y TRY    +DHF F +E+  F  +YL++ +YW K +  ILFY GNE +IE+F   +G +W++ E+L+A++VFAEHRYYG SLPFGN+SFS +++  YLT EQ +AD+A L+ YLK+ I GA  SPVIA GGSYGGMLAAW R+KY ++V G++++SAP    G+   C   F +++  ++  G   C+E+IR  W  I  +++   GL  LS  FHLC PLK   D   L ++L+     +++ N+PY A    PLPAWP++E CK   + +LSD   +L + + A+ +Y N T  + CLD       S   M W  Q C E+  P+C +G+HD++  +    +   +  C + +G++PRL+WI  ++ G +  S SNIIFSNG LDPWSAGG+ ++    +  + I +GAHH+DLR  +P+D   ++ AR +E   +++WI +
Sbjct:   13 YLTRYLSQQIDHFGF-DENRTFQQRYLVADQYWKKDHGPILFYTGNEGDIEWFCNNTGFMWDVAEELNAMLVFAEHRYYGESLPFGNESFSDSKHLNYLTSEQALADFAVLVEYLKTTIAGAQHSPVIAIGGSYGGMLAAWFRMKYPHVVVGALAASAPIWQFGDLVPCGTFFSIVTNDFKKSGMG-CSESIRNSWNAINRLSSTDAGLQWLSSTFHLCSPLKTLQDAAVLKNWLSETWVNLAMVNYPYKADFLQPLPAWPIQEVCKFLKDPSLSD-KLLLQNVFQAVNLYYNYTGEASCLDVAQTATKSLGEMGWYYQACTEMVMPLCTDGVHDMFEPQKWDFDA-LSEECYRMWGVRPRLSWILSMYGGKNITSHSNIIFSNGGLDPWSAGGVTQNITNSLVAVVIPDGAHHLDLRSRNPLDPKSVQQARAMEICLMKEWIEK 453          
BLAST of Lysosomal Pro-X carboxypeptidase vs. TrEMBL
Match: G1NQQ2 (Prolylcarboxypeptidase OS=Meleagris gallopavo OX=9103 GN=PRCP PE=4 SV=1)

HSP 1 Score: 389.808 bits (1000), Expect = 1.045e-126
Identity = 190/449 (42.32%), Postives = 284/449 (63.25%), Query Frame = 1
Query:  205 YETRYFQTYVDHFTFKNESLKFNLKYLISTKYWSKGN-VILFYCGNEANIEFFARISGNLWELGEQLSALVVFAEHRYYGSSLPFGNKSFSSAEYFGYLTVEQVIADYATLLTYLKSKITGASKSPVIAFGGSYGGMLAAWLRLKYTNIVAGSISSSAPFLMVGNYKNCNKIFKVISKVYQSQGSKLCAENIRKIWPIIKAINNRH-GLAHLSKIFHLCQPLKDVET---LISFLNNALFEISVANFPYAASVSVPLPAWPVREFCKRYTNGNLSDISNVLTSFYNAIQIYGNSTENSKCLDFQAADKNSFNSMAWEIQTCMELPFPMCINGIHDIYFKENLITEGEFNNFCLKKYGIKPRLNWINILFSGIHFQSLSNIIFSNGLLDPWSAGGILESSNKKIQLIKILNGAHHVDLRKSHPMDTTDIKMARKLEKTTIEKWISEWHEQ 1536
            Y TRY    +DHF F +E+L F  +YLI+ ++W K N  ILFY GNE +I +F   +G +W++ E+L+A++VFAEHRYYG SLPFGN+SFS +++  YLT EQ +AD+A L+ YLK  I GA  SPVIA GGSYGGMLAAW R+KY ++V G++++SAP    G+   C   F +++  ++  G+  C+E+IR  W  I  +++   GL  LS+ FHLC PLK+++    L S+L+    ++++ ++PY A    PLPAWP++E CK   + +LSD   +L + + AI IY N T  + C D       +   + W  Q C E+  PMC +G+HD++  +    E   ++ C K +G++PR +WI  ++ G +  S SNIIFSNG LDPWSAGG+ ++    +  I I +GAHH+DLR  +P D   ++ AR LE   +++WI++   Q
Sbjct:   35 YVTRYLTQQIDHFGF-DENLTFQQRYLIADQHWQKDNGPILFYTGNEGDITWFCNNTGFMWDVAEELNAMLVFAEHRYYGESLPFGNESFSDSKHLNYLTSEQALADFAVLIEYLKETIAGARHSPVIAIGGSYGGMLAAWFRMKYPHVVVGALAASAPIWQFGDLVPCGAYFTIVTNDFKKSGTG-CSESIRNSWNAINHLSSTDAGLQWLSRTFHLCSPLKNLQDALMLKSWLSETWIDLAMVDYPYKADFLEPLPAWPIQEVCKFLKDPSLSD-KLLLQNVFQAINIYYNYTGEASCFDMSETATKNLGQLGWYYQVCTEMVMPMCTDGVHDMFEPQKWDFEA-LSDECFKLWGVRPRPSWILSMYGGKNISSHSNIIFSNGGLDPWSAGGVTQNITDSLVAIVIPDGAHHLDLRSRNPCDPKSVQEARALEVHYMKQWIAKAKHQ 479          
BLAST of Lysosomal Pro-X carboxypeptidase vs. TrEMBL
Match: E9GMP5 (Uncharacterized protein OS=Daphnia pulex OX=6669 GN=DAPPUDRAFT_225197 PE=4 SV=1)

HSP 1 Score: 387.497 bits (994), Expect = 7.987e-126
Identity = 192/444 (43.24%), Postives = 282/444 (63.51%), Query Frame = 1
Query:  205 YETRYFQTYVDHFTFKNESLKFNLKYLISTKYWSKGN-VILFYCGNEANIEFFARISGNLWELGEQLSALVVFAEHRYYGSSLPFGNKSFSSAEYFGYLTVEQVIADYATLLTYLKSKITGASKSPVIAFGGSYGGMLAAWLRLKYTNIVAGSISSSAPFLMVGNYKNCNKIFKVISKVYQSQGSKLCAENIRKIWPIIKAI-NNRHGLAHLSKIFHLCQPL---KDVETLISFLNNALFEISVANFPYAASVSVPLPAWPVREFCKRYTNGNLSDISNVLTSFYNAIQIYGNSTENSKCLDFQAADKNSFNSMAWEIQTCMELPFPMCINGIHDIYFKENLITEGEFNNFCLKKYGIKPRLNWINILFSGIHFQSLSNIIFSNGLLDPWSAGGILESSNKKIQLIKILNGAHHVDLRKSHPMDTTDIKMARKLEKTTIEKWIS 1521
            ++T +F+  VDHF+F N+   +  +YL+++ YW +G   I FY GNE +IE+FA+ +G +W++ E+  A++VFAEHRYYG SLP+GNKS+S A+Y GYLT EQ +AD+A L+ Y+KS  +GA  SPVIAFGGSYGGML+AW+R+KY +I+ GSI++SAP L       C+   +V++  + S  ++ C+E IRK W  + +I +   G   L   ++LC PL    DV  L  +L N    +++ N+PYAA+   PLPA+PV+  C+  TN +L D S +L   +  + +Y N T  +KCLD       S   M W+ Q C E+  PMC +GI+D++  +    E +++  CLKK+ + PR     +++ G +  S SNI+FSNGLLDPWS GG+ +S +  I  I I  GAHH+DLR + P D   +  AR++EK  I KWIS
Sbjct:   22 WKTFFFKQQVDHFSFANQD-TYPQRYLVNSTYWKRGGGPIFFYTGNEGDIEWFAQNTGFMWDIAEEFGAMLVFAEHRYYGQSLPYGNKSYSDAKYLGYLTSEQALADFAELVAYIKSTNSGAVDSPVIAFGGSYGGMLSAWMRIKYPHIITGSIAASAPILQFTGLTPCDAFNRVVTADFASASTE-CSETIRKSWKSLSSILSQDDGKEWLRTHWNLCVPLNGTDDVVNLKDWLTNVWTNLAMVNYPYAANFLAPLPAYPVKAVCEHLTNSSLDDHS-LLDELFKGLSVYANFTGQTKCLDVSQQADQSLGDMGWDFQACTEMVMPMCGDGINDMFEAQPWNIE-KYSERCLKKWKVNPRPLMAPLIYGGKNISSSSNIVFSNGLLDPWSTGGVTKSLSDSIVAIIIPEGAHHLDLRAADPNDPPSVVKAREIEKQFIGKWIS 461          
BLAST of Lysosomal Pro-X carboxypeptidase vs. Ensembl Cavefish
Match: prcp (prolylcarboxypeptidase [Source:NCBI gene;Acc:103038921])

HSP 1 Score: 332.798 bits (852), Expect = 1.421e-107
Identity = 172/450 (38.22%), Postives = 265/450 (58.89%), Query Frame = 1
Query:  199 LTYETRYFQTYVDHFTFKNESLKFNLKYLISTKYWSKGN-VILFYCGNEANIEFFARISGNLWELGEQLSALVVFAEHRYYGSSLPFGNKSFSSAEYFGYLTVEQVIADYATLLTYLKSKITGASKSPVIAFGGSYGGMLAAWLRLKYTNIVAGSISSSAPFLMVGNYKNCNKIFKVISKVYQSQGSKLCAENIRKIWPIIKAINN-RHGLAHLSKIFHLCQPLK--DVETLISFLNNALFEISVANFPYAASVSVPLPAWPVREFCKRYTNGNLSDISN--VLTSFYNAIQIYGNSTENSKCLDFQAADKNSFNSMAWEIQTCMELPFPMCINGIHDIYFKENLITEGEFNNFCLKKYGIKPRLNWINILFSGIHFQSLSNIIFSNGLLDPWSAGGILESSNKKIQLIKIL--NGAHHVDLRKSHPMDTTDIKMARKLEKTTIEKWISE 1524
            ++Y T Y    +DHF F  E+  F  +YL++  +W K N  ILFY GNE +I +F   +G +W++ E+L A++VFAEHRYYG SLPFG++S+S+A+Y  YLT EQ +AD+A L+  LK    GA  SPVIA GGSYGGML+AWLR+KY + V G++++SAP     +   C   +K++++ +   G   C+ NIR+ W  I  +++   GL  LS+ F LC PLK  DV     +L      +++ ++PY A+   PLP WP++  C   +   ++D+ +  +L     A+ +Y N T N++CL+       +     W  Q+C E+  PMC +GI D+ F+        F++ C   +G++PR +W + ++ G +  S SNIIFSNG LDPW +GG+         L+ I+  +GAHH+DLR ++  D   +  AR +E    +KWI +
Sbjct:   51 VSYTTLYLDQQIDHFGFL-ENGTFKQRYLLNDLHWHKDNSPILFYTGNEGDITWFCNNTGFMWDIAEELGAMLVFAEHRYYGESLPFGDESYSNAKYLNYLTSEQALADFAVLIENLKKTYPGAQNSPVIAIGGSYGGMLSAWLRMKYPSAVVGALAASAPIWQFTDMVPCGDFYKIVTQDFAISGFN-CSNNIRRSWMAINNVSSTDEGLQWLSEEFRLCSPLKEEDVSGFKGWLQETWVNLAMVDYPYEANFLQPLPRWPIKVVCSYLS--FVTDVPDKELLHGISQAVNVYYNYTGNAECLNISLTATGNLGIRGWFYQSCTEMVMPMCTDGIQDM-FEPQPWNFQAFSDECYDLFGVRPREHWADTVYGGKNICSHSNIIFSNGRLDPWMSGGVTRLCGVSDSLVAIVIPDGAHHLDLRYNNEYDPETVIRARAVEVQYFKKWIKQ 495          
BLAST of Lysosomal Pro-X carboxypeptidase vs. Ensembl Cavefish
Match: dpp7 (dipeptidyl-peptidase 7 [Source:ZFIN;Acc:ZDB-GENE-050306-16])

HSP 1 Score: 275.789 bits (704), Expect = 4.358e-86
Identity = 160/461 (34.71%), Postives = 250/461 (54.23%), Query Frame = 1
Query:  196 KLTYETRYFQTYVDHFTFKN-ESLKFNLKYLISTKYWSKGN-VILFYCGNEANIEFFARISGNLWELGEQLSALVVFAEHRYYGSSLPFGNKSFSSAEYFGYLTVEQVIADYATLLTYLKSKITGASKSPVIAFGGSYGGMLAAWLRLKYTNIVAGSISSSAPFLMVGNYKNCNKIFKVISKVYQSQGSKLCAENIRKIWPIIKAINNRHGLAHLSKIFHLCQPL---KDVETLISFLNNALFEISVANFPYAASVSVPLPAWPVREFCKRYTNGNLSDISNVLTSFYNAIQIYGNSTENSKCLDF-----QAADKNS----FNSMAWEIQTCMELPFPMCINGIHDIYFKENLITEGEFNNFCLKKYGIKPRLNWINILFSGIHFQSLSNIIFSNGLLDPWSAGGILESSNKKIQLIKILNGAHHVDLRKSHPMDTTDIKMARKLEKTTIEKWISEWHEQ 1536
            K  ++ +YF   +DHF + +  +  +  +YLI+ +YW KG+  I FY GNE +I  FA  SG + EL  + +ALV+FAEH          +KSF      G LTVEQ +ADYA ++T LK ++  A K PVI FGGSYGGML+ ++R++Y NIV G++++SAP L      +  + F+ ++  +++  S +C +++R  +  ++ +  +   A +   F LC+     KD+  L  FL NA   +++ ++PY  S    +PA+PV+  C+   NG     + VL++  + + I  NST    C D      + AD       FNS AW+ Q C E+      N + D+ F     TE     +C +++ + PR  W+   + G    + SNIIFSNG LDPW+ GGI +S +  +  I I  GAHH+DLR S+P D   +  AR+ E   I +W+    E+
Sbjct:   23 KAQFKEKYFTQILDHFNYNSLGNGTYPQRYLITDQYWKKGSGPIFFYTGNEGDIWDFALNSGFVLELAVEQAALVIFAEH----------DKSFIIPN-VGLLTVEQALADYAVMITDLKKELR-AEKCPVIVFGGSYGGMLSVYMRVRYPNIVTGALAASAPILSTAGMGDSGQFFRDVTADFEN-CSPVCKDSVRSAFQKLQTLAQQEDYAGIQSAFSLCKTPSSSKDIHQLNGFLRNAFTLLAMMDYPYKTSFMSVMPAFPVKVACETMLNG-----TEVLSALRDTVGIVYNSTGEHACYDLYSLYVECADPTGCGLGFNSYAWDYQACTEIEMCFESNNVTDM-FPPMPFTESMREEYCARRWAVVPRPGWLKTQYWGDALSTASNIIFSNGDLDPWANGGIRKSLSDSLIAINIPEGAHHLDLRASNPADPDSVIKARQTEAKLIAQWVKTAREK 464          
BLAST of Lysosomal Pro-X carboxypeptidase vs. Ensembl Cavefish
Match: ENSAMXT00000015346.2 (serine protease 16 [Source:NCBI gene;Acc:103045980])

HSP 1 Score: 125.561 bits (314), Expect = 2.203e-30
Identity = 107/446 (23.99%), Postives = 192/446 (43.05%), Query Frame = 1
Query:  232 VDHFTFKNESLKFNLKYLISTKYWSKGNVILF-YCGNEANIEFFARISGNLWELGEQLSALVVFAEHRYYGSSLPFGNKSFSSAEYFGYLTVEQVIADYATLLTYLKSKITGASKSPVIAFGGSYGGMLAAWLRLKYTNIVAGSISSSAPFLMVGNYKNCNKIFKVISKVYQSQGSKLCAENIRKIWPIIKAINNRHGLAHLSKIFHLCQPLKDVETLISFLNNALFEISVANFPYAASVSVPLPAWPVREFCKRYTNGNLSDIS--NVLTSFYNAIQIYGNSTENSKC---------LDFQAADKNSFNSMAWEIQTCMELPF-PMCINGIHDIYFKENLITEGEFNN--FCLKKYGIKPRLNWINILFSGIHFQSLSNIIFSNGLLDPWSAGGILE--SSNKKIQLIKILNGAHHVDLRKSHPMDTTDIKMARKLEKTTIEKWI 1518
            +DHF  +N +  F  ++ I+  YW   +  +F Y G E  +  F+ ++G+   + +Q  AL+V  EHR+YG S+  G       +   YL+ +Q +AD A    ++  K     ++  I+FGGSY G L+AW R K+ ++V G+++SSAP     ++ +   +           GS+ C + + + +  ++A   R     + K F  C+  K +E     L  +L +I +    Y   V +      +   C   TN + + +              IY  + E   C         LD       S     W  QTC E  F   C +         NL TE +     F + ++ +   + + N+ + G   Q+   +++ NG  DPW A  ++   ++  K + I I + AH  D+  +   D   +  AR+  ++ +E W+
Sbjct:   59 LDHFNRRN-TRTFPQRFFINEAYWKHPHGPVFLYIGGEGPLSEFSVLAGHHVTMAKQQGALLVALEHRFYGRSIIPGGLE---PQNLQYLSSQQALADLAAFHQHISQKYNLTYRNIWISFGGSYAGALSAWFRGKFPHLVYGAVASSAPVQAKLDFSSYTTVVGRSLMDESVGGSEKCVKAVWEAFAAVEAALLRGEETQVGKDFSCCETPKSLEDQTELL-RSLADIFMGTVQYNEEVGL----LTIARLCSIMTNQSKAYVEGKEAYDRLVRLAAIY-RTMEKETCLEVSYEKSILDLNTTTHVSSGYRQWFYQTCTEFGFYQTCEDATCPFSRMMNLQTEIQLCPLLFSIPQHTLPSNIAFTNLYYGGDQPQT-QRVLYVNGDTDPWMALSVVRNGTNKDKHRAILIHSSAHCADMNPTRARDRASLLQARQEIESLVEAWL 493          
BLAST of Lysosomal Pro-X carboxypeptidase vs. Ensembl Cavefish
Match: prss16 (putative serine protease K12H4.7 [Source:NCBI gene;Acc:103026864])

HSP 1 Score: 94.3597 bits (233), Expect = 3.757e-20
Identity = 101/440 (22.95%), Postives = 179/440 (40.68%), Query Frame = 1
Query:  208 ETRYFQTYVDHFTFKNESLKFNLKYLISTKYWSKGNVILFYCGNEANIEFFARISGNLWELGEQLSALVVFAEHRYYGSSLPFGNKSFSSAEYFGYLTVEQVIADYATLLTYLKSKITGASKSPVIAFGGSYGGMLAAWLRLKYTNIVAGSISSSAPFLMVGNYKNCNKIFKVISKVYQSQGSKLCAENIRKIWPIIKA-INNRHGLAHLSKIFHLCQPLK-----DVETLISFLNNALFEISVANFPYAASVSVPLPAWPVREFCKRYTNGNLSDISNVLTSFYNAIQIYGNSTENSKCLDFQAAD------KNSFNSMA------WEIQTCMELPFPMCINGIHDIY----FKENLITEGEFNNFCLKKYGIKPRLNWINILFSGIHFQSLSNIIFSNGLLDPWSAGGILESSNKKIQLIKILNGAHHVDLRKSHPMD 1461
            E  +F   +DHF    +S  +  +Y I+ +++  G  +    G E          G      E+  AL +  EHR+YG S P  + S  S     +L+  Q +AD A   + + ++    + +  +AFGGSY G LAAW RLKY ++V  S+++SAP     N+    +  +V+ K  +++  + C   ++K    + A + +     +++K F LC  L+     D   L+  L     ++   N    A   V      ++  C    +  L +  +     Y A+      T    C D Q +         S+   A      W  QTC E  F    +  +  +     K +L    +  N       +   +   N  + G   +S + I+F NG +DPW A G++ +   ++  + I   AH  ++  +   D
Sbjct:   51 EEYWFIQRLDHFN-GADSRVWKQRYFINDRFYKPGGPVFLMIGGEGPANPAWMQYGTWLNYAEKFGALCLLLEHRFYGKSHPTEDLSVES---LRFLSSRQALADLAHFRS-VTAETRKLTSNKWVAFGGSYPGSLAAWFRLKYPHLVHASVATSAPVYATVNF---TEYLEVVQKSLEAENPQ-CPVLVKKASDTLMARLKDPKTYDNITKDFRLCSKLEIQSDMDSAYLLETLAGNFMDVVQYNEDNRAFEGVLGTNITIKVLCDVMLDSLLGEPYDR----YAAVARLLQKTFLQSCTDAQYSQYVREMSNTSWTGPAASGGRQWVYQTCAEFGFYQSTDSQNQPFGGFPLKYHLRQCNDIYNL---NSSVADAVQQTNEEYGGYDIRS-TRIVFPNGSIDPWHALGVISNITDELPAVFIKGTAHCANMYPARAED 473          
BLAST of Lysosomal Pro-X carboxypeptidase vs. Ensembl Sea Lamprey
Match: dpp7 (dipeptidyl-peptidase 7 [Source:ZFIN;Acc:ZDB-GENE-050306-16])

HSP 1 Score: 136.346 bits (342), Expect = 1.178e-36
Identity = 80/265 (30.19%), Postives = 127/265 (47.92%), Query Frame = 1
Query:  763 CAENIRKIWPIIKAINNRHGLAHLSKIFHLCQP---LKDVETLISFLNNALFEISVANFPYAASVSVPLPAWPVREFCKRYTNGNLSDISNVLTSFYNAIQIYGNSTENSKCLD-----FQAADKNSF----NSMAWEIQTCMELPFPMCINGIHDIYFKENLITEGEFNNFCLKKYGIKPRLNWINILFSGIHFQSLSNIIFSNGLLDPWSAGGILESSNKKIQLIKILNGAHHVDLRKSHPMDTTDIKMARKLEKTTIEKWIS 1521
            C + +R  +  +K + ++   A +++   LCQ      DV  +  +  N    +++ ++PYAAS    LPA PV   C    N       + L     A+ ++ N++  +KCLD      + AD        +S+AW+ Q C E+      N + D+ F     T      +C K++G+ PR  W+   + G    S SNIIFSNG LDPW  GG        +  +K++ GAHH+DLR S+P D   +  ARKLE   +  W++
Sbjct:    9 CPDIVRAGFIELKKLADKQEWAQIAQRMRLCQAPSSAADVRHMYGWARNTFTYLAMLDYPYAASFMGSLPANPVNVACDLLLNSK-----DPLDGLMQAVALFYNTSGTAKCLDPAAEFIECADPTGCGLGPDSLAWDYQACTEINLLCSTNNVSDM-FPALPYTAAARREYCAKRWGVVPRETWLATQYWGKDVNSSSNIIFSNGNLDPWGNGGFQHDVGGNVA-VKVIGGAHHLDLRYSNPADPESVVTARKLESALLHTWLA 266          
BLAST of Lysosomal Pro-X carboxypeptidase vs. Ensembl Sea Lamprey
Match: ENSPMAT00000005355.1 (pep scaffold:Pmarinus_7.0:GL477796:147175:163357:-1 gene:ENSPMAG00000004846.1 transcript:ENSPMAT00000005355.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 133.65 bits (335), Expect = 9.631e-34
Identity = 120/463 (25.92%), Postives = 198/463 (42.76%), Query Frame = 1
Query:  208 ETRYFQTYVDHFTFKNESLKFNLKYLISTKYWSK--GNVILFYCGNEANIEFFARISGNLWELGEQLSALVVFAEHRYYGSSL-PFGNKSFSSAEYFGYLTVEQVIADYATLLTYLKSKITGASKSPVIAFGGSYGGMLAAWLRLKYTNIVAGSISSSAPFLMVGNYKNCNKIFKVISKVYQSQGSKLCAENIRKIWPIIKAINNRHGLAHLSKIFHLCQPLKDVETLISFLNNALFEISVANFPYAASVSVPLPAWPVREFCKRYTNGNLSDISNVLTSFYNAIQIYGNSTENSKCLDFQA------ADKNSFNSMAWEIQTCMELPFPMCINGIHDIYFKENLITEGEFNNFCLKKYGIKPRLNWINILFS----GIHFQSLSNIIFSNGLLDPWSAGGILESSNKKIQLIKILNGAHHVDLRKSHPMDTTDIKMARKLEKTTIEKWISEWHEQIAKIYLL 1557
            + R+ Q  +DHF  + +   +  +Y ++   W K  G V LF  G E  +  +  ++G   EL  +  ALV   EHR+YG S+ P G K     E   YL+ +Q +AD A+   YL         +  I FGGSY G L+AW RLK+ ++V  +++SSAP     +++  NK+           GS  C   +R+ +  + A      L+ L + F  C P    + L  F +N L +I ++   Y    +  +P   +R  C    +   S    ++    N + I   +  ++   +F A      A +       W  QTC E  +        D  F + L+T     + C + +G+ P      + F+    G      S I+F NG +DPW A  +L +  +    I I   AH  ++  + P D   +  AR      I++ + +W  Q  +  LL
Sbjct:   71 QERFLQQPLDHFDRRTKE-TYKQRYWVNNMNWKKPDGPVFLFI-GGEGALSEYDVLAGEHVELSAKYGALVAAVEHRFYGESINPDGLK----MENLQYLSSQQALADLASFHAYLVDTYNLTRNNTWICFGGSYPGSLSAWFRLKFPHLVFAAVASSAPVRAQLDFQGYNKVVAASLADKVVGGSDKCLSRVREAFATVDAKLTGKELSGLERDFKSCVPFAGPDDLALFASN-LADIFMSVVQY----NREMPNSDIRALCAAMIDTGKSAYQQLVALNENYLSIEQRNCSDNTYANFIADLSNTTATRVGVGMRQWTYQTCTEFGYYQTCVSERDCPFLQ-LMTLSWNLDLCDRVFGVDPASVASAVRFTNEYYGADHPRGSRILFVNGDIDPWHALSVLRNETRSEVAIFINGTAHCANMSPTSPSDPPSLTNAR----LKIDEQVGDWLHQAKRRQLL 517          
BLAST of Lysosomal Pro-X carboxypeptidase vs. Ensembl Sea Lamprey
Match: ENSPMAT00000003379.1 (pep scaffold:Pmarinus_7.0:GL476462:377682:381797:1 gene:ENSPMAG00000003081.1 transcript:ENSPMAT00000003379.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 77.0258 bits (188), Expect = 1.634e-16
Identity = 50/174 (28.74%), Postives = 86/174 (49.43%), Query Frame = 1
Query:  268 FNLKYLISTKYWSKGNVILF-YCGNEANIEFFARISGNLWELGEQLSALVVFAEHRYYGSSLPFGNKSFSSAEYFGYLTVEQVIADYATLLTYLKSKITGASKSPV-IAFGGSYGGMLAAWLRLKYTNIVAGSISSSAPFLMVGNYKNCNKIFKVISKVYQSQGSKLCAENIRK 783
            F  +  +++ +W +    +F Y G E+ +       G    L +   AL+V AEHR+YG S+   N+   S +   YLT+ Q +AD   +  Y  S   G  +    ++FGGSY G L+AW RLK+  ++  +++SSAP     +Y   +++     +     GS  C  ++R+
Sbjct:   16 FKQRVWVNSLFWKRPRGPVFLYIGGESALNSNDVFVGQHVRLAQSHGALLVAAEHRFYGKSV---NEEGLSDKNLRYLTISQALADLVRVHHYYVSDEFGLKQGHAWVSFGGSYPGSLSAWFRLKHPELIHTAVASSAPVRAQLDYAGYDEVVGQSLRNSMVGGSDECVSSMRE 186          
BLAST of Lysosomal Pro-X carboxypeptidase vs. Ensembl Nematostella
Match: EDO36007 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SJW1])

HSP 1 Score: 367.851 bits (943), Expect = 1.659e-122
Identity = 171/438 (39.04%), Postives = 269/438 (61.42%), Query Frame = 1
Query:  232 VDHFTFKNESLKFNLKYLISTKYWSKGNVILFYCGNEANIEFFARISGNLWELGEQLSALVVFAEHRYYGSSLPFGNKSFSSAEYFGYLTVEQVIADYATLLTYLKSKITGASKSPVIAFGGSYGGMLAAWLRLKYTNIVAGSISSSAPFLMVGNYKNCNKIFKVISKVYQSQGSKLCAENIRKIWPIIKAIN-NRHGLAHLSKIFHLCQPLK---DVETLISFLNNALFEISVANFPYAASVSVPLPAWPVREFCKRYTNGNLSDISNVLTSFYNAIQIYGNSTENSKCLDFQAADKNSFNSMAWEIQTCMELPFPMCINGIHDIYFKENLITEGEFNNFCLKKYGIKPRLNWINILFSGIHFQSLSNIIFSNGLLDPWSAGGILESSNKKIQLIKILNGAHHVDLRKSHPMDTTDIKMARKLEKTTIEKWISEWHE 1533
            +DHF F+  S  F+ +YL++   W KG  I FY GNE +I +FA  +G +W+  ++  A++VFAEHRYYG +LPFG +S+ S +Y GYL+ EQ +AD+ATL+ ++K    GA+ SPVIA GGSYGGML++W+R+KY N+V  ++++SAP L       C    ++++K +   G   C  +IRK W +I+ +   + G   L+ +F+ C P+K   +V  L  +L+     +++ N+PYAA+   PLPAWP+++ C   T+ +L D++ +L +   A+ +Y NS+  +KC +      +S     W+ Q C E+  PMC +G++D+ FK        F   C   YG+KPR  W+ + + G    + SNIIFSNGLLDPW AGG+ +S +  +  + +  GAHH+DLR S+P D   +  AR+ EK  + +WISE+++
Sbjct:    1 LDHFNFRT-SATFSQRYLVNIANWRKGGPIFFYTGNEGDITWFANNTGFMWDNAKEFGAMLVFAEHRYYGETLPFGKRSYESPKYLGYLSSEQALADFATLIRHIKLTTPGATGSPVIAIGGSYGGMLSSWIRMKYPNLVTAALAASAPILYFQGLTPCEGFNEIVTKDFHRDGGDSCVNSIRKSWSVIEKLGATQSGRKTLTSVFNTCSPIKTKYNVTQLQDWLSETWANLAMVNYPYAATFLEPLPAWPIKKVCSHLTDADLPDVA-LLKAVAGAVGVYYNSSGQAKCFNLSQQAVSSLGDKGWDFQACTEMVMPMCSDGVNDM-FKPVKWDFEAFAESCQGSYGVKPRQYWVEVQYGGRDISAHSNIIFSNGLLDPWFAGGVTKSLSPSLVAVLVEEGAHHLDLRHSNPADPPSLIKARQTEKEYLHRWISEYYK 435          
BLAST of Lysosomal Pro-X carboxypeptidase vs. Ensembl Nematostella
Match: EDO48107 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RK54])

HSP 1 Score: 300.442 bits (768), Expect = 2.898e-96
Identity = 173/454 (38.11%), Postives = 251/454 (55.29%), Query Frame = 1
Query:  205 YETRYFQTYVDHFTFKNESLKFNLKYLISTKYWSKGNVILFYCGNEANIEFFARISGNLWELGEQLSALVVFAEHRYYGSSLPFGNKSFSSAEYFGYLTVEQVIADYATLLTYLKSKITGASKSPVIAFGGSYGGMLAAWLRLKYTNIVAGSISSSAPFLMVGNYKNCNKIFKVISKVYQSQGSKLCAENIRKIWPIIKAINNR--HGLAHLSKIFHLCQPLKDVET---LISFLNNALFEISVANFPYAASVSVPLPAWPVREFCKRYTNGNLSDISNVLTSFYNAIQIYGNSTENS-KCLD-----FQAADKNSFN----SMAWEIQTCMELPFPMCINGIHDIYFKENLITEGEFNNFCLKKYGIKPRLNWINILFSGIHFQSLSNIIFSNGLLDPWSAGGILESSNKKIQLIKILNGAHHVDLRKSHPMDTTDIKMARKLEKTTIEKWIS 1521
            ++T  F+  VDHF F  +S  F  +YL + KYW     I FY GNE  I  F   SG ++E  +  SALV+F EHRYYG SLPFG  SF   E  GYL++EQ +AD+ATL+  LK +   A + PV++FGGSYGGML+A+LR KY N++  ++++SAP   + +    +  F  +++ +++   K C + +R  +  +  +      GL  +SK F LC+PLK  +    LI ++ NA   I++ ++PYA     PLPA PV   CK      L+  S+ L+   +A  +  N T  + KC D      + AD         ++AW+ Q C ELP P   N + D+ F     T     ++C K + +KPRL W  I   G    + SNIIFSNG LDPW  GG+L+S +  +  + +  GAHH+DLR S+P D   +  AR++E   I KWIS
Sbjct:    3 FKTGTFEQTVDHFNFI-QSGTFKQRYLYTEKYWDGKGPIFFYSGNEGGITGFWENSGFVFEAAKNFSALVIFGEHRYYGESLPFGQDSFK-IENIGYLSIEQALADFATLIPALKKQFK-AEEKPVVSFGGSYGGMLSAYLRFKYPNVIQAALAASAPIYFIADLSIRDFFFPAVTRDFKNADPK-CPDLVRAGFIELDNLKKEGLKGLDAISKAFKLCKPLKSADQINHLIGWIRNAFTIIAMCDYPYATDFLAPLPANPVNYACKL-----LATASDRLSGLADAAGLAYNGTSGTLKCFDPWTEFVECADPTGCGLGNANLAWDYQACTELPMPAGTNNVTDM-FPVLPWTLDMRADYCQKHWQVKPRLEWPGISLWGRDISTASNIIFSNGNLDPWRPGGVLKSVSPSLVAVLVEGGAHHLDLRSSNPEDPPSVVAAREMELELIRKWIS 446          
BLAST of Lysosomal Pro-X carboxypeptidase vs. Ensembl Nematostella
Match: EDO29742 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T2S3])

HSP 1 Score: 194.897 bits (494), Expect = 6.927e-58
Identity = 107/267 (40.07%), Postives = 157/267 (58.80%), Query Frame = 1
Query:  205 YETRYFQTYVDHFTFKNESLKFNLKYLISTKYWSKGNVILFYCGNEANIEFFARISGNLWELGEQLSALVVFAEHRYYGSSLPFGNKSFSSAEYFGYLTVEQVIADYATLLTYLKSKITGASKSPVIAFGGSYGGMLAAWLRLKYTNIVAGSISSSAPFLMVGNYKNCNKIFKVISKVYQSQGSKLCAENIRKIWPIIKAINNR--HGLAHLSKIFHLCQPLKDVET---LISFLNNALFEISVANFPYAASVSVPLPAWPVREFCK 990
            ++T  F+  VDHF F  +S  F  +YL + KYW     I FY GNE  I  F   SG ++E  +  SALV+F EHRYYG SLPFG  SF   E  GYL++EQ +AD+ATL+  LK +   A + PV++FGGSYGGML+A+LR KY N++  ++++SAP   + +    +  F  +++ +++   K C + +R  +  +  +      GL  +SK F LC+PLK  +    LI ++ NA   I++ ++PYA     PLPA PV   CK
Sbjct:    1 FKTGTFEQTVDHFNFI-QSGTFKQRYLYTEKYWDGKGPIFFYSGNEGGITGFWENSGFVFEAAKNFSALVIFGEHRYYGESLPFGQDSF-KIENIGYLSIEQALADFATLIPALKKQFK-AEEKPVVSFGGSYGGMLSAYLRFKYPNVIQAALAASAPIYFIADLSIRDFFFPAVTRDFKNADPK-CPDLVRAGFIELDNLKKEGLKGLDAISKAFKLCKPLKSADQINHLIGWIRNAFTIIAMCDYPYATDFLAPLPANPVNYACK 263          
BLAST of Lysosomal Pro-X carboxypeptidase vs. Ensembl Nematostella
Match: EDO31220 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SYK4])

HSP 1 Score: 145.976 bits (367), Expect = 7.198e-38
Identity = 110/447 (24.61%), Postives = 202/447 (45.19%), Query Frame = 1
Query:  220 FQTYVDHFTFKNESLKFNLKYLISTKYW-SKGNVILFYCGNEANIEFFARISGNLWELGEQLSALVVFAEHRYYGSSLPFGNKSFSSAEYFGYLTVEQVIADYATLLTYLKSKITGASKSPVIAFGGSYGGMLAAWLRLKYTNIVAGSISSSAPFLMVGNYKNCNKIFKVISKVYQSQGSKLCAENIRKIWPIIKAINNRHGLAHLSKIFHLCQPLKDVETLISFLNN-ALFEISVANFPYAASVSVPLPAWPVREFCKRYTNGNLSDISNVLTSFYNAIQIYGNSTENS-----KCLDFQAADKNSFNSM-AWEIQTCMELP-FPMCINGIHDIYFKE-NLITEGEFNN--FCLKKYGIKPRLNWINILFSGIHFQSLSNIIFSNGLLDPWSAGGILESSNKKIQLIKILNGAHHVDLRKSHPMDTTDIKMARKLEKTTIEKWISE 1524
            F+ Y+DHF F      +  +Y ++  +W      +L Y G E+ +       G++ ++ ++  AL+   EHRYYG S  FG     +  Y   L+ +  +AD A  + + K+K     K+  I +GGSY G L+AW R+KY ++V G+++SSAP     ++K+ N +           GSKLC  NI + +  +  + +      L K F  C  +  +     F +N A F + +  +      +  +P   +   CK+  N + S   ++   +   IQ   + ++ S     K +  Q  D + F+ +  W  Q+C +   F  C  G H ++ K   +I + +     F +    +K R+N+ N  + G   +  S I+F NG +DPW +  ++ +       + I   +H  ++  + P D   +  AR+     + +W+ E
Sbjct:   61 FEQYIDHFEFTPRPRTYLQRYWMNRAFWKGPDGPVLLYVGGESVLSGGYIAGGHIVDIAKEYGALLFAVEHRYYGKSNFFGCLKTKNMRY---LSSQLALADLAQFVAHAKNKFGLTDKNKWITYGGSYPGSLSAWFRIKYPHLVIGAVASSAPVEAQTDFKDYNNVVASSLSSPLVGGSKLCMHNIEEAFKFVDRLLDTKNFKTLEKDFIACNDISKLNDTWMFASNLAGFFMGLVQY------NNQVPGINIAYVCKQMNNASRSPYKSLSILYKQQIQKTASCSDFSYENFMKTVKTQKRDPDGFDMIRQWYYQSCTQFGYFQTCEPGTHCVFSKRLGIINDMDLCQEVFEIALGQLKARINFTNEYYGGKRPRG-SKIVFVNGSIDPWHSLSVVTNQTSSEVAVFIPGTSHCANMGANQPNDPPALVEARRRVTAIVGEWLKE 497          
BLAST of Lysosomal Pro-X carboxypeptidase vs. Ensembl Nematostella
Match: EDO43517 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RYG7])

HSP 1 Score: 110.153 bits (274), Expect = 5.903e-26
Identity = 117/455 (25.71%), Postives = 182/455 (40.00%), Query Frame = 1
Query:  217 YFQTYVDHFTFKNESLKFNLKYLISTKYWSKGNVILFYCGNEANIEFFARISGNLWELGEQLSALVVFAEHRYYGSSLPFGNKSFSSAEYFGYLTVEQVIADYATLLTYLKSKITGASKSPVIAFGGSYGGMLAAWLRLKYTNIVAGSISSSAPFLMVGNYKNCNKIFKVISKVYQSQGSKLCAENIRKIWPIIKA-INNRHGLAHLSKIFHLCQPL-----KDVETLISFLNNALFEISVANFPYAASVSVPLPAWPVREFCKRYTNGNLSDISNVLTSFYNAI-QIYGNSTENSKCLDFQAADKNSFNSM--------------AWEIQTCMELPFPMCINGIHDIYFKENLITEGEFNNFCLKKYGIKPRLNWINILFSGIHFQSLSNIIFSNGLLDPWSAGGILESSNKKIQLIKILNGAHHVDLRKSHPMDTTDIKMARKLEKTTIEKWI 1518
            +F   +DHF   N        Y   T   +K + +    G E  I     + GN+ +  E   A+    EHR+YG S P   +S  S     YL  EQ +AD A     +  K    + S  I+FGGSY G L+AWLRLKY +++ G+++SSAP L   N+    +  +V++   ++ G   C +NI      I+  ++   G   L+ +F +C+PL      DV T  S L      +   N    A   VP     +   C    + +L           + I   YG      KCLD  A+ +N+ NS+               W  QTC E  F    +  +  + K           F L KY I+  ++     F+  +  S      +N     +   GI  S +    +      AH  ++      D+  +K AR++ K  I KW+
Sbjct:   18 WFIQRLDHFDDSNTETWKQRFYYNDTFRKTKDSPVFLMVGGEGAISPVWVLIGNMMKYAEGFGAMAFILEHRFYGQSHP---RSDMSDANLKYLNSEQALADLAAFRQAMSVKFN-LTDSKWISFGGSYPGSLSAWLRLKYPHLIHGAVASSAPVLAQLNFP---EYLEVVTASLETTGPD-CTKNIANATAAIEELLDADEGTKKLTNLFRVCEPLNRRNDNDVSTFSSNLAGLFMGVVQYNKDNRAFEGVPGTNITIATVCGIMNDKSLGPALMRYAKLNSLILDTYG-----EKCLD--ASYQNAINSLRNVSWDSSAAEGGRQWTYQTCTEFGFYQTTDSDNQPFGKR----------FPL-KYSIQQCMDVFGEAFNSSNLASGIRQTNTN-----YGGKGIASSRDIVFVVFYPTGTAHCANMYPESDSDSPQLKQAREVIKQHIAKWL 441          
BLAST of Lysosomal Pro-X carboxypeptidase vs. Ensembl Medaka
Match: prcp (prolylcarboxypeptidase [Source:NCBI gene;Acc:101171930])

HSP 1 Score: 348.977 bits (894), Expect = 6.938e-114
Identity = 179/461 (38.83%), Postives = 270/461 (58.57%), Query Frame = 1
Query:  187 SNYKLTYETRYFQTYVDHFTFKNESLKFNLKYLISTKYWSKGN-VILFYCGNEANIEFFARISGNLWELGEQLSALVVFAEHRYYGSSLPFGNKSFSSAEYFGYLTVEQVIADYATLLTYLKSKITGASKSPVIAFGGSYGGMLAAWLRLKYTNIVAGSISSSAPFLMVGNYKNCNKIFKVISKVYQSQGSKLCAENIRKIWPIIKAINN----RHGLAHLSKIFHLCQPLK---DVETLISFLNNALFEISVANFPYAASVSVPLPAWPVREFCKRYTNGNLSDISNVLTSFYNAIQIYGNSTENSKCLDFQAADKNSFNSMAWEIQTCMELPFPMCINGIHDIYFKENLITEGEFNNFCLKKYGIKPRLNWINILFSGIHFQSLSNIIFSNGLLDPWSAGGILESSNKKIQLIKILNGAHHVDLRKSHPMDTTDIKMARKLEKTTIEKWISEWHEQIAK 1545
            S   + Y+T YF   ++HF F  E   F  +YL++ K+W + +  ILFY GNE +I +F   +G +WE+ E+L A++VFAEHRYYG SLPFG  S+S +++  YLT EQ +AD+A L+  LKSK+    +SPVI+ GGSYGGML+AWLR+KY N+V G++++SAP         C   +K++++ +   G   C   IR+ W   KAINN      GL  LS+ F LC PLK   D      +L      +++ ++PY AS   PLPAWP++  CK     + +   ++L     A ++Y N T +S CL+      +S  ++ W  Q C E+  PMC +G+ D++  E+   +  F++ C   +G++PR +W   L+ G    S SNIIFSNG LDPWSAGG+  +  + +  I I +GAHH+DLR S  +D   ++ AR LE    ++WI +  ++  +
Sbjct:   46 SEPPIIYKTFYFNQRINHFGFL-EDGTFKQRYLVADKHWQEPDGPILFYTGNEGDITWFCNNTGFMWEIAEELGAMLVFAEHRYYGESLPFGQDSYSDSKHLNYLTSEQALADFAVLIQNLKSKM---PESPVISVGGSYGGMLSAWLRMKYPNVVVGALAASAPIWQFPRMVGCGDFYKIVTQDFAKSGQN-CDVTIRRSW---KAINNLSSTASGLQWLSEEFSLCSPLKTKTDAVIFKGWLQETWVNLAMVDYPYEASFLQPLPAWPIQVVCKYLAFDSKASDYDLLHGVSQAAKVYYNYTGSSSCLNTSQTATSSLGALGWTYQACTEMVMPMCTDGVQDMFEPEDWNFQA-FSDECYSMFGVRPREDWAGTLYGGKDISSHSNIIFSNGGLDPWSAGGVTYNITESLVSIMIPDGAHHLDLRYSTDLDPPSVRAARALELKFFQEWIDKTKKRTGR 497          
BLAST of Lysosomal Pro-X carboxypeptidase vs. Ensembl Medaka
Match: dpp7 (dipeptidyl peptidase 7 [Source:NCBI gene;Acc:101156583])

HSP 1 Score: 310.071 bits (793), Expect = 5.416e-99
Identity = 174/452 (38.50%), Postives = 253/452 (55.97%), Query Frame = 1
Query:  205 YETRYFQTYVDHFTFKN-ESLKFNLKYLISTKYWSKGN-VILFYCGNEANIEFFARISGNLWELGEQLSALVVFAEHRYYGSSLPFGNKSFSSAEYFGYLTVEQVIADYATLLTYLKSKITGASKSPVIAFGGSYGGMLAAWLRLKYTNIVAGSISSSAPFLMVGNYKNCNKIFKVISKVYQSQGSKLCAENIRKIWPIIKAINNRHGLAHLSKIFHLCQP---LKDVETLISFLNNALFEISVANFPYAASVSVPLPAWPVREFCKRYTNGNLSDISNVLTSFYNAIQIYGNSTENSKCLDF-----QAADKNS----FNSMAWEIQTCMELPFPMCINGIHDIYFKENLITEGEFNNFCLKKYGIKPRLNWINILFSGIHFQSLSNIIFSNGLLDPWSAGGILESSNKKIQLIKILNGAHHVDLRKSHPMDTTDIKMARKLEKTTIEKWI 1518
            +  +YF   VDHF F +  +  FN +YLI+ ++W + +  + FY GNE +I  FA  SG + EL  Q  ALV+FAEHRYYG SLPFGN SFS  E  G LTVEQ +ADYA ++T LK ++ GA++SPVIAFGGSYGGML+ ++RLKY NIVAG++++SAP L      +  + F+ ++  ++ + S  C   +   +  ++    R   +H+     LCQP    +DV  L   L NA   +++ ++PY+      LPA PV+  C     G      ++LT+  +   +  NS+    C D      + AD       FNS+AW+ Q C E+      N + D+ F     TE     +C K++G++PR  W+ + F G    + SNIIFSNG LDPW+ GG+  S +  +  I I  GAHH+DLR S+  D   +  ARK+E   I  W+
Sbjct:   35 FTEKYFSQVVDHFNFNSLGNRTFNQRYLITDRFWRRSSGPVFFYTGNEGDIWEFALNSGFIMELAAQQEALVIFAEHRYYGRSLPFGNNSFSIPE-VGLLTVEQALADYALMITELKLQL-GAAQSPVIAFGGSYGGMLSVYMRLKYPNIVAGALAASAPILSTAGLGDPRQFFRDVTADFE-RVSPACRGAVTAAFQQLREAAERRDYSHIQAELSLCQPPSSAQDVHQLYGLLRNAFTLMAMLDYPYSTHFMGSLPANPVKVACDTMLGG-----PDLLTNLRDTAGMVYNSSGLLPCFDLYSLYVECADPTGCGLGFNSLAWDYQACTEIEMCYESNNVTDM-FPAMTFTEDARQLYCSKRWGVQPRPGWLRLQFWGDDLSAASNIIFSNGDLDPWANGGVRTSLSPSLIAINISGGAHHLDLRGSNAADPESVIKARKMEAELIAAWV 477          
BLAST of Lysosomal Pro-X carboxypeptidase vs. Ensembl Medaka
Match: ENSORLT00000010681.2 (thymus-specific serine protease-like [Source:NCBI gene;Acc:101175669])

HSP 1 Score: 127.487 bits (319), Expect = 2.725e-31
Identity = 117/453 (25.83%), Postives = 208/453 (45.92%), Query Frame = 1
Query:  277 KYLISTKYWSK--GNVILFYCGNEANIEFFARISGNLWELGEQLSALVVFAEHRYYGSSL-PFGNKSFSSAEYFGYLTVEQVIADYATLLTYLKSKITGASKSPVIAFGGSYGGMLAAWLRLKYTNIVAGSISSSAPFLMVGNYKNCNKIFKVI--SKVYQSQGSKL---------------CAENIRKIWPIIKAINNRHGLAHLSKIFHLCQPLKDVETLISFLNNALFEISVANFPYAASVSVPLPAWPVREFCKRYTNGNLSDISNVLTSFYNAIQIYGNSTENSKCLDFQAAD------KNSFNS-----MAWEIQTCMELPF-PMCINGIHDIYFKENLITEGEFNNFCLKKYGIKPRLNWINILFSGIHFQS----LSNIIFSNGLLDPWSAGGILESSNKKIQLIKILNGAHHVDLRKSHPMDTTDIKMARKLEKTTIEKWISEW 1527
            K+ ++  +W +  G V LF  G E  I  F  ++G+  E+ +Q  AL++  EHR+YG S+ P G K+ S A+    L+ +Q +AD AT   Y+      +S++P I+FGGSY G L+AW R K+ ++V  +++SSAP     ++ + N +   +  S    +  S L               C   +++ +  ++A      L+ ++  F+ CQ  K+++  I  + N L ++ +    Y     +      V+E C   TN   S+ S   +  + ++Q+Y +STE+ KCLD    +        S +S       W  QTC E  F   C +         NL  +      C   +GI       NI F+  ++         +++ NG +DPW    +++   +++Q + I + AH  D+     +    ++ AR+     IEK +S+W
Sbjct:   14 KFFVNEAHWQRPDGPVFLFI-GGEGPIFSFDVLAGHHVEMAQQHGALLLAVEHRFYGDSINPDGLKTESLAD----LSSQQALADLATFHGYICRSFNLSSRNPWISFGGSYSGALSAWFRGKFPSLVYAAVASSAPIKAKLDFSDYNHVNVRVNASTCLHACDSSLYLSDCRFWLSLLFLQCWAQVQQAFAAVEAELLTGNLSQVAGDFNCCQIPKNLDDQIELMQN-LADLFMGTVQYNEEGVL----LSVKELCDLMTNMCNSEPS---SRSFVSVQVYRSSTED-KCLDVSHEETIKHLMDTSVHSSRRAERQWTYQTCTEFGFYQTCEDSTCPFSGLINLQAQ---TKLCTAVFGISQHSLPSNIAFTNSYYGGDEPHTHRVLYINGGIDPWKELSVVQ-GGQEVQSVFIEDTAHCADMSSRRVVKRDSLRRARQ----EIEKQVSDW 444          
BLAST of Lysosomal Pro-X carboxypeptidase vs. Ensembl Medaka
Match: prss16 (putative serine protease K12H4.7 [Source:NCBI gene;Acc:101158124])

HSP 1 Score: 114.39 bits (285), Expect = 9.699e-27
Identity = 108/461 (23.43%), Postives = 193/461 (41.87%), Query Frame = 1
Query:  208 ETRYFQTYVDHFTFKNESLKFNLKYLISTKYWSKGNVILFYCGNEANIEFFARISGNLWELGEQLSALVVFAEHRYYGSSLPFGNKSFSSAEYFGYLTVEQVIADYATLLTYLKSKITGASKSPVIAFGGSYGGMLAAWLRLKYTNIVAGSISSSAPFLMVGNYKNCNKIFKVISKVYQSQGSKLCAENIRKIWP-IIKAINNRHGLAHLSKIFHLCQPLK-----DVETLISFLNNALFEISVANFPYAASVSVPLPAWPVREFCKRYTNGNLSDISNVLTSFYNAIQIYGNSTENSKCLDFQAADKNSFNSMA--------------WEIQTCMELPFPMCINGIHDIY----FKENLITEGEFNNFCLKKYGIKPRLNWINILFSGIHFQSLSNIIFSNGLLDPWSAGGILESSNKKIQLIKILNGAHHVDLRKSHPMDTTDIKMARKLEKTTIEKWI 1518
            E ++F   +DHF    +S  +  +Y ++  ++  G  +    G E         +G      E+L AL +  EHRYYG S P  + S ++  Y   L+  Q +AD A   T +  +  G + +  +AFGGSY G LAAW RLKY ++V  S+++SAP     N+    +  +V+ +   S+ +K C   ++K    +++ + +     +++K F+LC  L+     D    +  L     ++   N        V      ++  C   ++ +L D      +    +      T + KCLD  A+  N    M               W  QTC E  F    +  +  +        L    +F N   ++  +   +   N  + G + +S S I+F NG +DPW A GI +     +  + I   AH  ++  +   D   + +AR      +++W+
Sbjct:   45 EEQWFTQKLDHFN-GADSRAWKQRYFLNEAFYKPGGPVFLMIGGEGPANPAWMKNGTWLIYAEKLGALCLMLEHRYYGKSHPTLDLSTNNLRY---LSSRQALADLAHFRTVM-GEAQGLTNNKWVAFGGSYPGSLAAWFRLKYPHLVHASVATSAPVHATVNFP---EYLEVVWRSLASENAK-CPLLVKKASDSLVEKLKDPETFDNITKDFNLCSKLQIQTEMDSAYFLEMLAGNFMDVVQYNEDNREFEGVQGGNITIKVLCDVMSDPSLGDAYARYAAVARLLM----DTFSLKCLD--ASFSNYLRDMTNTSWEGPSANGGRQWVYQTCTEFGFYQSTDSPNQPFTGFPLDYQLKQCADFYNISAEQ--VAQAVAQTNEYYGGYNIKS-SRIVFPNGSIDPWHALGITQDITADLPAVFIKGTAHCANMYPARSQDLPQLSLARDHVLLLLQQWL 487          
BLAST of Lysosomal Pro-X carboxypeptidase vs. Planmine SMEST
Match: SMESG000074421.1 (SMESG000074421.1)

HSP 1 Score: 998.808 bits (2581), Expect = 0.000e+0
Identity = 486/487 (99.79%), Postives = 486/487 (99.79%), Query Frame = 1
Query:   97 MKLYLFLIQMHCLFLQQSFSYNKSKEIDKLSNYKLTYETRYFQTYVDHFTFKNESLKFNLKYLISTKYWSKGNVILFYCGNEANIEFFARISGNLWELGEQLSALVVFAEHRYYGSSLPFGNKSFSSAEYFGYLTVEQVIADYATLLTYLKSKITGASKSPVIAFGGSYGGMLAAWLRLKYTNIVAGSISSSAPFLMVGNYKNCNKIFKVISKVYQSQGSKLCAENIRKIWPIIKAINNRHGLAHLSKIFHLCQPLKDVETLISFLNNALFEISVANFPYAASVSVPLPAWPVREFCKRYTNGNLSDISNVLTSFYNAIQIYGNSTENSKCLDFQAADKNSFNSMAWEIQTCMELPFPMCINGIHDIYFKENLITEGEFNNFCLKKYGIKPRLNWINILFSGIHFQSLSNIIFSNGLLDPWSAGGILESSNKKIQLIKILNGAHHVDLRKSHPMDTTDIKMARKLEKTTIEKWISEWHEQIAKIYLL 1557
            MKLYLFLIQMHCLFLQQSFSYNKSKEIDKLSNYKLTYETRYFQTYVDHFTFKNESLKFNLKYLISTKYWSKGNVILFYCGNEANIEFFARISGNLWELGEQLSALVVFAEHRYYGSSLPFGNKSFSSAEYFGYLTVEQVIADYATLLTYLKSKITGASKSPVIAFGGSYGGMLAAWLRLKYTNIVAGSISSSAPFLMVGNYKNCNKIFKVISKVYQSQGSKLCAENIRKIWPIIKAINNRHGLAHLSKIFHLCQPLKDVETLISFLN ALFEISVANFPYAASVSVPLPAWPVREFCKRYTNGNLSDISNVLTSFYNAIQIYGNSTENSKCLDFQAADKNSFNSMAWEIQTCMELPFPMCINGIHDIYFKENLITEGEFNNFCLKKYGIKPRLNWINILFSGIHFQSLSNIIFSNGLLDPWSAGGILESSNKKIQLIKILNGAHHVDLRKSHPMDTTDIKMARKLEKTTIEKWISEWHEQIAKIYLL
Sbjct:    1 MKLYLFLIQMHCLFLQQSFSYNKSKEIDKLSNYKLTYETRYFQTYVDHFTFKNESLKFNLKYLISTKYWSKGNVILFYCGNEANIEFFARISGNLWELGEQLSALVVFAEHRYYGSSLPFGNKSFSSAEYFGYLTVEQVIADYATLLTYLKSKITGASKSPVIAFGGSYGGMLAAWLRLKYTNIVAGSISSSAPFLMVGNYKNCNKIFKVISKVYQSQGSKLCAENIRKIWPIIKAINNRHGLAHLSKIFHLCQPLKDVETLISFLNYALFEISVANFPYAASVSVPLPAWPVREFCKRYTNGNLSDISNVLTSFYNAIQIYGNSTENSKCLDFQAADKNSFNSMAWEIQTCMELPFPMCINGIHDIYFKENLITEGEFNNFCLKKYGIKPRLNWINILFSGIHFQSLSNIIFSNGLLDPWSAGGILESSNKKIQLIKILNGAHHVDLRKSHPMDTTDIKMARKLEKTTIEKWISEWHEQIAKIYLL 487          
BLAST of Lysosomal Pro-X carboxypeptidase vs. Planmine SMEST
Match: SMESG000074421.1 (SMESG000074421.1)

HSP 1 Score: 981.474 bits (2536), Expect = 0.000e+0
Identity = 477/478 (99.79%), Postives = 477/478 (99.79%), Query Frame = 1
Query:  124 MHCLFLQQSFSYNKSKEIDKLSNYKLTYETRYFQTYVDHFTFKNESLKFNLKYLISTKYWSKGNVILFYCGNEANIEFFARISGNLWELGEQLSALVVFAEHRYYGSSLPFGNKSFSSAEYFGYLTVEQVIADYATLLTYLKSKITGASKSPVIAFGGSYGGMLAAWLRLKYTNIVAGSISSSAPFLMVGNYKNCNKIFKVISKVYQSQGSKLCAENIRKIWPIIKAINNRHGLAHLSKIFHLCQPLKDVETLISFLNNALFEISVANFPYAASVSVPLPAWPVREFCKRYTNGNLSDISNVLTSFYNAIQIYGNSTENSKCLDFQAADKNSFNSMAWEIQTCMELPFPMCINGIHDIYFKENLITEGEFNNFCLKKYGIKPRLNWINILFSGIHFQSLSNIIFSNGLLDPWSAGGILESSNKKIQLIKILNGAHHVDLRKSHPMDTTDIKMARKLEKTTIEKWISEWHEQIAKIYLL 1557
            MHCLFLQQSFSYNKSKEIDKLSNYKLTYETRYFQTYVDHFTFKNESLKFNLKYLISTKYWSKGNVILFYCGNEANIEFFARISGNLWELGEQLSALVVFAEHRYYGSSLPFGNKSFSSAEYFGYLTVEQVIADYATLLTYLKSKITGASKSPVIAFGGSYGGMLAAWLRLKYTNIVAGSISSSAPFLMVGNYKNCNKIFKVISKVYQSQGSKLCAENIRKIWPIIKAINNRHGLAHLSKIFHLCQPLKDVETLISFLN ALFEISVANFPYAASVSVPLPAWPVREFCKRYTNGNLSDISNVLTSFYNAIQIYGNSTENSKCLDFQAADKNSFNSMAWEIQTCMELPFPMCINGIHDIYFKENLITEGEFNNFCLKKYGIKPRLNWINILFSGIHFQSLSNIIFSNGLLDPWSAGGILESSNKKIQLIKILNGAHHVDLRKSHPMDTTDIKMARKLEKTTIEKWISEWHEQIAKIYLL
Sbjct:    1 MHCLFLQQSFSYNKSKEIDKLSNYKLTYETRYFQTYVDHFTFKNESLKFNLKYLISTKYWSKGNVILFYCGNEANIEFFARISGNLWELGEQLSALVVFAEHRYYGSSLPFGNKSFSSAEYFGYLTVEQVIADYATLLTYLKSKITGASKSPVIAFGGSYGGMLAAWLRLKYTNIVAGSISSSAPFLMVGNYKNCNKIFKVISKVYQSQGSKLCAENIRKIWPIIKAINNRHGLAHLSKIFHLCQPLKDVETLISFLNYALFEISVANFPYAASVSVPLPAWPVREFCKRYTNGNLSDISNVLTSFYNAIQIYGNSTENSKCLDFQAADKNSFNSMAWEIQTCMELPFPMCINGIHDIYFKENLITEGEFNNFCLKKYGIKPRLNWINILFSGIHFQSLSNIIFSNGLLDPWSAGGILESSNKKIQLIKILNGAHHVDLRKSHPMDTTDIKMARKLEKTTIEKWISEWHEQIAKIYLL 478          
BLAST of Lysosomal Pro-X carboxypeptidase vs. Planmine SMEST
Match: SMESG000074424.1 (SMESG000074424.1)

HSP 1 Score: 519.235 bits (1336), Expect = 0.000e+0
Identity = 245/456 (53.73%), Postives = 322/456 (70.61%), Query Frame = 1
Query:  163 KSKEID-KLSNYKLTYETRYFQTYVDHFTFKNESLKFNLKYLISTKYWSKGNVILFYCGNEANIEFFARISGNLWELGEQLSALVVFAEHRYYGSSLPFGNKSFSSAEYFGYLTVEQVIADYATLLTYLKSKITGASKSPVIAFGGSYGGMLAAWLRLKYTNIVAGSISSSAPFLMVGNYKNCNKIFKVISKVYQSQGSKLCAENIRKIWPIIKAINNRHGLAHLSKIFHLCQPLKDVETLISFLNNALFEISVANFPYAASVSVPLPAWPVREFCKRYTNGNLSDISNVLTSFYNAIQIYGNSTENSKCLDFQAADKNSFNSMAWEIQTCMELPFPMCINGIHDIYFKENLITEGEFNNFCLKKYGIKPRLNWINILFSGIHFQSLSNIIFSNGLLDPWSAGGILESSNKKIQLIKILNGAHHVDLRKSHPMDTTDIKMARKLEKTTIEKWISEW 1527
            K K+ D  +  YK  Y+T+YF TY+DHFT+KN+S KF +KYLIST+ W KGN ILFYCGNE +IE FA  SG +WELGEQLS +V+FAEHR+YGSSLPFG  S++ +++FGYL  EQ +ADYA LLTYLK+ I GA  SPVIAFGGSYGGMLAAW R KY NIVAGSI++SAP LMVGN +NCN  F+V+++ ++ +G++ C +N+R  W +IK +++  GL +LSKIFH C+PLK  ++LI  L + LF++ +AN+PY  +   P+PAWPV  FCK  +   +++   +L +FY  +Q++ N T   +CL          +   W +QTC ELP PMC +GI D+++ EN   +   +  C   YG+ PR  W   LF G   ++ SNI+FSNG LDPWSAGG+  SSN  +Q+I I NGAHHVDLR SHP DT+DI+ ARKLEK  I KWISEW
Sbjct:   23 KIKKFDVNIEQYK--YDTKYFSTYLDHFTYKNDSAKFQMKYLISTENWVKGNAILFYCGNEGSIELFANNSGFVWELGEQLSTMVIFAEHRFYGSSLPFGKMSYNGSQHFGYLNSEQALADYADLLTYLKATIAGAENSPVIAFGGSYGGMLAAWFRQKYPNIVAGSIAASAPVLMVGNVENCNYAFRVLTRAFKVKGNEACVDNVRNAWSVIKKMDDPVGLTNLSKIFHTCKPLKSADSLIGLLTDGLFDMGMANYPYPTNFLGPMPAWPVTVFCKPLST-PINNPIQLLNAFYTGVQVFFNYTGQIRCLPANPITP-GLDDNGWNVQTCTELPMPMCTDGITDMFY-ENRFDKNVNDKNCHLSYGVSPRWGWGQTLFWGKRLEAASNIVFSNGYLDPWSAGGVYNSSNPSVQIILIKNGAHHVDLRSSHPSDTSDIRFARKLEKNAIMKWISEW 473          
BLAST of Lysosomal Pro-X carboxypeptidase vs. Planmine SMEST
Match: SMESG000074424.1 (SMESG000074424.1)

HSP 1 Score: 518.85 bits (1335), Expect = 0.000e+0
Identity = 245/456 (53.73%), Postives = 322/456 (70.61%), Query Frame = 1
Query:  163 KSKEID-KLSNYKLTYETRYFQTYVDHFTFKNESLKFNLKYLISTKYWSKGNVILFYCGNEANIEFFARISGNLWELGEQLSALVVFAEHRYYGSSLPFGNKSFSSAEYFGYLTVEQVIADYATLLTYLKSKITGASKSPVIAFGGSYGGMLAAWLRLKYTNIVAGSISSSAPFLMVGNYKNCNKIFKVISKVYQSQGSKLCAENIRKIWPIIKAINNRHGLAHLSKIFHLCQPLKDVETLISFLNNALFEISVANFPYAASVSVPLPAWPVREFCKRYTNGNLSDISNVLTSFYNAIQIYGNSTENSKCLDFQAADKNSFNSMAWEIQTCMELPFPMCINGIHDIYFKENLITEGEFNNFCLKKYGIKPRLNWINILFSGIHFQSLSNIIFSNGLLDPWSAGGILESSNKKIQLIKILNGAHHVDLRKSHPMDTTDIKMARKLEKTTIEKWISEW 1527
            K K+ D  +  YK  Y+T+YF TY+DHFT+KN+S KF +KYLIST+ W KGN ILFYCGNE +IE FA  SG +WELGEQLS +V+FAEHR+YGSSLPFG  S++ +++FGYL  EQ +ADYA LLTYLK+ I GA  SPVIAFGGSYGGMLAAW R KY NIVAGSI++SAP LMVGN +NCN  F+V+++ ++ +G++ C +N+R  W +IK +++  GL +LSKIFH C+PLK  ++LI  L + LF++ +AN+PY  +   P+PAWPV  FCK  +   +++   +L +FY  +Q++ N T   +CL          +   W +QTC ELP PMC +GI D+++ EN   +   +  C   YG+ PR  W   LF G   ++ SNI+FSNG LDPWSAGG+  SSN  +Q+I I NGAHHVDLR SHP DT+DI+ ARKLEK  I KWISEW
Sbjct:   15 KIKKFDVNIEQYK--YDTKYFSTYLDHFTYKNDSAKFQMKYLISTENWVKGNAILFYCGNEGSIELFANNSGFVWELGEQLSTMVIFAEHRFYGSSLPFGKMSYNGSQHFGYLNSEQALADYADLLTYLKATIAGAENSPVIAFGGSYGGMLAAWFRQKYPNIVAGSIAASAPVLMVGNVENCNYAFRVLTRAFKVKGNEACVDNVRNAWSVIKKMDDPVGLTNLSKIFHTCKPLKSADSLIGLLTDGLFDMGMANYPYPTNFLGPMPAWPVTVFCKPLST-PINNPIQLLNAFYTGVQVFFNYTGQIRCLPANPITP-GLDDNGWNVQTCTELPMPMCTDGITDMFY-ENRFDKNVNDKNCHLSYGVSPRWGWGQTLFWGKRLEAASNIVFSNGYLDPWSAGGVYNSSNPSVQIILIKNGAHHVDLRSSHPSDTSDIRFARKLEKNAIMKWISEW 465          
BLAST of Lysosomal Pro-X carboxypeptidase vs. Planmine SMEST
Match: SMESG000048843.1 (SMESG000048843.1)

HSP 1 Score: 267.7 bits (683), Expect = 6.843e-83
Identity = 158/451 (35.03%), Postives = 251/451 (55.65%), Query Frame = 1
Query:  232 VDHFTF----KNESLKFNLKYLISTKYWSKGNVILFYCGNEANIEFFARISGNLWELGEQLSALVVFAEHRYYGSSLPFGNKSFSSAEYFGYLTVEQVIADYATLLTYLKSKITGASKSPVIAFGGSYGGMLAAWLRLKYTNIVAGSISSSAPFLMVGNYKNCNKIFKVISKVYQSQGSKLCAENIRKIWP--IIKAINNRHGLAHLSKIFHLCQPL---KDVETLISFLNNALFEISVANFPYAASVSVPLPAWPVREFCKRYTNGNLSDISNVLTSFYNAIQIYGNSTENSKC-----LDFQAADKNSF----NSMAWEIQTCMELPFPMCINGIHDIYFKENLITEGEFNNFCLKKYGIKPRLNWINILFSGIHFQSLSNIIFSNGLLDPWSAGGILESSNKKIQLIKIL--NGAHHVDLRKSHPMDTTDIKMARKLEKTTIEKWISE 1524
            +DHF F    +  ++KF  +YL   K++  G  I FYCGNE +IE F   +G ++EL  + +ALVVF EHRYYG SLPFG+ +     Y  YL+VEQ +AD+  +++Y+K K   A+ S VIAFGGSYGG LAA++R KY NIV G++++S+P   V   K  +K F++I+K +     K C E ++  +   I  A     GL  +S+    C+PL    DV   + +L NA   +++ ++PY  +    LPA+PV   C+      L++ +N + +   A  ++ N ++  KC     L  + +D        +S+AW+ Q C E+      N      F +  +T+ + +  C+KK+ I+   N +  L  G   ++ +N+IFSNG LDPWS GGI+ +S+ +   + +L   GAHH+DLR S+P D   ++  R++E+  I  W+  
Sbjct:   35 LDHFNFLSVSRGYAIKFKQRYLYEDKWYKPGGPIFFYCGNEGSIEGFWNNTGFMFELAPKFNALVVFGEHRYYGVSLPFGSINSFQQPYIQYLSVEQALADFVYMISYVKDKFN-ANNSDVIAFGGSYGGCLAAYMRFKYPNIVLGALAASSPIGWVSGSKGFHKFFEIITKDFYDINPK-CVEIVQDGFEEMITLAGKGLTGLDTISRYLKTCKPLTSMADVTYAMKWLRNAFVMLAMMDYPYKTNFMGSLPAFPVNVSCQNI----LANKNNPIIALREAAAVFYNQSKPLKCFSPMDLYIECSDITGCGLGPDSLAWDFQACTEMKLYDDNNATSADMFPDLPLTKKDVDRHCMKKFEIQRAPNQLKFLEWGNDVRTATNVIFSNGNLDPWSLGGIVSNSSLQPSSVALLIQGGAHHLDLRSSNPADPPSVRTVRQIEEKYIRAWLGH 479          
The following BLAST results are available for this feature:
BLAST of Lysosomal Pro-X carboxypeptidase vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
PRCP7.708e-12138.80prolylcarboxypeptidase [Source:HGNC Symbol;Acc:HGN... [more]
PRCP8.653e-11838.39prolylcarboxypeptidase [Source:HGNC Symbol;Acc:HGN... [more]
DPP74.565e-9437.39dipeptidyl peptidase 7 [Source:HGNC Symbol;Acc:HGN... [more]
PRCP3.229e-6040.34prolylcarboxypeptidase [Source:HGNC Symbol;Acc:HGN... [more]
PRCP1.476e-4953.69prolylcarboxypeptidase [Source:HGNC Symbol;Acc:HGN... [more]
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BLAST of Lysosomal Pro-X carboxypeptidase vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
pcp-54.252e-9233.73Prolyl carboxy peptidase like protein 5 [Source:U... [more]
pcp-54.252e-9233.73Prolyl carboxy peptidase like protein 5 [Source:U... [more]
pcp-53.896e-9133.73Prolyl carboxy peptidase like protein 5 [Source:U... [more]
pcp-15.485e-6230.93Putative serine protease pcp-1 [Source:UniProtKB/... [more]
pcp-15.485e-6230.93Putative serine protease pcp-1 [Source:UniProtKB/... [more]
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BLAST of Lysosomal Pro-X carboxypeptidase vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
CG24931.049e-11138.19gene:FBgn0032864 transcript:FBtr0081363[more]
CG24931.049e-11138.19gene:FBgn0032864 transcript:FBtr0332970[more]
CG37347.564e-3123.94gene:FBgn0038700 transcript:FBtr0339152[more]
CG37347.564e-3123.94gene:FBgn0038700 transcript:FBtr0083755[more]
CG99531.407e-2724.78gene:FBgn0035726 transcript:FBtr0076898[more]
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BLAST of Lysosomal Pro-X carboxypeptidase vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
prcp4.611e-11037.60prolylcarboxypeptidase (angiotensinase C) [Source:... [more]
dpp71.152e-9636.19dipeptidyl-peptidase 7 [Source:ZFIN;Acc:ZDB-GENE-0... [more]
dpp71.641e-9636.19dipeptidyl-peptidase 7 [Source:ZFIN;Acc:ZDB-GENE-0... [more]
dpp71.641e-9636.19dipeptidyl-peptidase 7 [Source:ZFIN;Acc:ZDB-GENE-0... [more]
dpp71.641e-9636.19dipeptidyl-peptidase 7 [Source:ZFIN;Acc:ZDB-GENE-0... [more]
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BLAST of Lysosomal Pro-X carboxypeptidase vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
prcp2.202e-12639.59prolylcarboxypeptidase [Source:NCBI gene;Acc:78009... [more]
prcp3.369e-12140.60prolylcarboxypeptidase [Source:NCBI gene;Acc:78009... [more]
prcp4.437e-12140.60prolylcarboxypeptidase [Source:NCBI gene;Acc:78009... [more]
prcp4.532e-12140.23prolylcarboxypeptidase [Source:NCBI gene;Acc:78009... [more]
prcp5.899e-12140.60prolylcarboxypeptidase [Source:NCBI gene;Acc:78009... [more]
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BLAST of Lysosomal Pro-X carboxypeptidase vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 4
Match NameE-valueIdentityDescription
Prcp1.248e-12239.87prolylcarboxypeptidase (angiotensinase C) [Source:... [more]
Prcp1.328e-11138.39prolylcarboxypeptidase (angiotensinase C) [Source:... [more]
Dpp79.900e-8636.48dipeptidylpeptidase 7 [Source:MGI Symbol;Acc:MGI:1... [more]
Prss161.082e-2623.18protease, serine 16 (thymus) [Source:MGI Symbol;Ac... [more]
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BLAST of Lysosomal Pro-X carboxypeptidase vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q7TMR0|PCP_MOUSE8.728e-12239.87Lysosomal Pro-X carboxypeptidase OS=Mus musculus O... [more]
sp|Q5RBU7|PCP_PONAB1.280e-12139.02Lysosomal Pro-X carboxypeptidase OS=Pongo abelii O... [more]
sp|Q2TA14|PCP_BOVIN1.540e-12039.12Lysosomal Pro-X carboxypeptidase OS=Bos taurus OX=... [more]
sp|P42785|PCP_HUMAN3.702e-12038.80Lysosomal Pro-X carboxypeptidase OS=Homo sapiens O... [more]
sp|Q9UHL4|DPP2_HUMAN2.192e-9337.39Dipeptidyl peptidase 2 OS=Homo sapiens OX=9606 GN=... [more]
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BLAST of Lysosomal Pro-X carboxypeptidase vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A0X3PYJ75.320e-12944.50Uncharacterized protein OS=Schistocephalus solidus... [more]
A0A1D5PVG83.463e-12842.54Prolylcarboxypeptidase OS=Gallus gallus OX=9031 GN... [more]
U3JZA64.766e-12741.80Prolylcarboxypeptidase OS=Ficedula albicollis OX=5... [more]
G1NQQ21.045e-12642.32Prolylcarboxypeptidase OS=Meleagris gallopavo OX=9... [more]
E9GMP57.987e-12643.24Uncharacterized protein OS=Daphnia pulex OX=6669 G... [more]
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BLAST of Lysosomal Pro-X carboxypeptidase vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 4
Match NameE-valueIdentityDescription
prcp1.421e-10738.22prolylcarboxypeptidase [Source:NCBI gene;Acc:10303... [more]
dpp74.358e-8634.71dipeptidyl-peptidase 7 [Source:ZFIN;Acc:ZDB-GENE-0... [more]
ENSAMXT00000015346.22.203e-3023.99serine protease 16 [Source:NCBI gene;Acc:103045980... [more]
prss163.757e-2022.95putative serine protease K12H4.7 [Source:NCBI gene... [more]
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BLAST of Lysosomal Pro-X carboxypeptidase vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 3
Match NameE-valueIdentityDescription
dpp71.178e-3630.19dipeptidyl-peptidase 7 [Source:ZFIN;Acc:ZDB-GENE-0... [more]
ENSPMAT00000005355.19.631e-3425.92pep scaffold:Pmarinus_7.0:GL477796:147175:163357:-... [more]
ENSPMAT00000003379.11.634e-1628.74pep scaffold:Pmarinus_7.0:GL476462:377682:381797:1... [more]
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BLAST of Lysosomal Pro-X carboxypeptidase vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Lysosomal Pro-X carboxypeptidase vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO360071.659e-12239.04Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO481072.898e-9638.11Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO297426.927e-5840.07Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO312207.198e-3824.61Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO435175.903e-2625.71Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Lysosomal Pro-X carboxypeptidase vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 4
Match NameE-valueIdentityDescription
prcp6.938e-11438.83prolylcarboxypeptidase [Source:NCBI gene;Acc:10117... [more]
dpp75.416e-9938.50dipeptidyl peptidase 7 [Source:NCBI gene;Acc:10115... [more]
ENSORLT00000010681.22.725e-3125.83thymus-specific serine protease-like [Source:NCBI ... [more]
prss169.699e-2723.43putative serine protease K12H4.7 [Source:NCBI gene... [more]
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BLAST of Lysosomal Pro-X carboxypeptidase vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000074421.10.000e+099.79SMESG000074421.1[more]
SMESG000074421.10.000e+099.79SMESG000074421.1[more]
SMESG000074424.10.000e+053.73SMESG000074424.1[more]
SMESG000074424.10.000e+053.73SMESG000074424.1[more]
SMESG000048843.16.843e-8335.03SMESG000048843.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30029010 ID=SMED30029010|Name=Lysosomal Pro-X carboxypeptidase|organism=Schmidtea mediterranea sexual|type=transcript|length=1722bp
GCTGGTTTCGTTGTTACTTTGTAATATTTGAATTTATTAAAAATAAAGCT
AAAAGACATAATATTAAATTTCTAATATTATTCATGTAGTTTCCAGATGA
AATTATATTTATTCTTAATTCAAATGCATTGCTTGTTTTTGCAGCAAAGT
TTCTCGTATAATAAAAGCAAGGAAATTGATAAATTGTCCAATTATAAACT
AACATATGAAACCAGATATTTTCAAACATACGTTGACCATTTTACTTTTA
AAAACGAAAGCTTAAAATTCAATTTGAAATACTTAATATCCACCAAGTAT
TGGTCGAAAGGAAATGTGATTTTATTTTATTGTGGCAATGAGGCAAATAT
TGAATTTTTTGCGAGAATCTCGGGGAACTTATGGGAACTTGGCGAGCAGT
TATCGGCCCTGGTTGTATTTGCAGAACACAGATATTACGGTTCATCACTG
CCTTTTGGCAACAAATCATTTTCCTCGGCTGAATACTTTGGATATCTTAC
AGTGGAACAAGTTATAGCAGATTATGCAACACTTTTGACCTATCTTAAAT
CAAAAATAACTGGTGCTAGCAAATCCCCTGTAATTGCGTTTGGCGGCTCT
TACGGAGGAATGCTAGCTGCATGGCTCAGATTAAAATATACAAATATTGT
TGCTGGATCGATTTCATCTTCTGCGCCGTTTCTAATGGTTGGCAATTACA
AAAATTGCAATAAAATTTTCAAAGTCATATCCAAAGTTTACCAATCACAA
GGCAGTAAATTATGCGCTGAAAACATCCGCAAAATTTGGCCAATTATAAA
AGCAATAAATAATCGTCATGGTTTAGCACATCTATCAAAAATATTTCATT
TGTGTCAACCTTTGAAAGACGTGGAGACTTTAATCAGTTTTTTAAATAAT
GCCTTATTTGAAATCAGTGTGGCGAATTTTCCTTACGCGGCATCCGTCAG
TGTTCCGTTGCCTGCCTGGCCTGTTCGCGAATTTTGTAAACGATATACAA
ATGGAAATCTTTCAGATATTTCAAATGTTTTAACTTCGTTTTACAATGCC
ATCCAGATATATGGAAATTCTACAGAAAACTCCAAATGCTTAGATTTTCA
AGCTGCGGACAAAAACAGTTTTAACTCAATGGCGTGGGAAATTCAAACCT
GTATGGAACTTCCATTTCCTATGTGTATAAACGGAATTCATGACATATAT
TTTAAAGAGAATTTAATAACGGAAGGAGAATTTAATAATTTTTGTTTGAA
AAAATATGGGATTAAACCTCGCTTGAATTGGATAAATATTCTTTTTTCGG
GTATTCACTTTCAGTCTTTATCCAACATAATATTTAGTAACGGGCTACTG
GATCCTTGGTCTGCTGGCGGAATCCTTGAATCTTCGAATAAAAAGATTCA
ATTAATTAAAATACTTAATGGAGCTCATCATGTGGATTTGCGAAAATCTC
ATCCAATGGACACGACTGACATTAAAATGGCAAGAAAATTAGAAAAAACA
ACGATAGAAAAGTGGATAAGTGAATGGCATGAACAAATTGCTAAAATTTA
TTTACTATGAAATTTTTGTGTTTCAAATTATATTTATGTAAGTGTTAAGG
TATTAATATTCTATATATGTAGAAAGTATGTAAGGTCCCAACCGAGTCAC
CTGTAAAAATAACTGTATTGGAACGGTCTGGAGTGAATGTTATGTTGATT
TATGTTAACTATTAACCACAAT
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protein sequence of SMED30029010-orf-1

>SMED30029010-orf-1 ID=SMED30029010-orf-1|Name=SMED30029010-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=488bp
MKLYLFLIQMHCLFLQQSFSYNKSKEIDKLSNYKLTYETRYFQTYVDHFT
FKNESLKFNLKYLISTKYWSKGNVILFYCGNEANIEFFARISGNLWELGE
QLSALVVFAEHRYYGSSLPFGNKSFSSAEYFGYLTVEQVIADYATLLTYL
KSKITGASKSPVIAFGGSYGGMLAAWLRLKYTNIVAGSISSSAPFLMVGN
YKNCNKIFKVISKVYQSQGSKLCAENIRKIWPIIKAINNRHGLAHLSKIF
HLCQPLKDVETLISFLNNALFEISVANFPYAASVSVPLPAWPVREFCKRY
TNGNLSDISNVLTSFYNAIQIYGNSTENSKCLDFQAADKNSFNSMAWEIQ
TCMELPFPMCINGIHDIYFKENLITEGEFNNFCLKKYGIKPRLNWINILF
SGIHFQSLSNIIFSNGLLDPWSAGGILESSNKKIQLIKILNGAHHVDLRK
SHPMDTTDIKMARKLEKTTIEKWISEWHEQIAKIYLL*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000034epidermis
PLANA:0002032epidermal cell
PLANA:0003116parenchymal cell
Vocabulary: INTERPRO
TermDefinition
IPR042269Ser_carbopepase_S28_SKS
IPR029058AB_hydrolase
IPR008758Peptidase_S28
Vocabulary: molecular function
TermDefinition
GO:0008236serine-type peptidase activity
GO:0004180carboxypeptidase activity
GO:0008233peptidase activity
GO:0016787hydrolase activity
Vocabulary: biological process
TermDefinition
GO:0006508proteolysis
GO:0002155regulation of thyroid hormone mediated signaling pathway
GO:0002353plasma kallikrein-kinin cascade
GO:0003085negative regulation of systemic arterial blood pressure
GO:0042593glucose homeostasis
GO:0043535regulation of blood vessel endothelial cell migration
GO:0060055angiogenesis involved in wound healing
GO:0097009energy homeostasis
GO:2000377regulation of reactive oxygen species metabolic process
Vocabulary: cellular component
TermDefinition
GO:0005764lysosome
GO:0045178basal part of cell
GO:0070062extracellular exosome
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR042269Serine carboxypeptidase S28, SKS domainGENE3DG3DSA:1.20.120.980coord: 203..373
e-value: 5.9E-139
score: 466.0
IPR008758Peptidase S28PFAMPF05577Peptidase_S28coord: 46..465
e-value: 3.3E-76
score: 256.8
IPR029058Alpha/Beta hydrolase foldGENE3DG3DSA:3.40.50.1820coord: 41..474
e-value: 5.9E-139
score: 466.0
IPR029058Alpha/Beta hydrolase foldSUPERFAMILYSSF53474alpha/beta-Hydrolasescoord: 45..262
NoneNo IPR availablePANTHERPTHR11010PROTEASE S28 PRO-X CARBOXYPEPTIDASE-RELATEDcoord: 17..480
NoneNo IPR availablePANTHERPTHR11010:SF38LYSOSOMAL PRO-X CARBOXYPEPTIDASEcoord: 17..480
NoneNo IPR availableSIGNALP_EUKSignalP-noTMSignalP-noTMcoord: 1..20
score: 0.552