CRAL-TRIO domain-containing protein

Overview
NameCRAL-TRIO domain-containing protein
Smed IDSMED30028995
Length (bp)1363
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of CRAL-TRIO domain-containing protein (SMED30028995) t-SNE clustered cells

Violin plots show distribution of expression levels for CRAL-TRIO domain-containing protein (SMED30028995) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of CRAL-TRIO domain-containing protein (SMED30028995) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for CRAL-TRIO domain-containing protein (SMED30028995) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30028995

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 3

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
parapharyngeal regionSMED30028995h1SMcG0022485 SmedASXL_015467SmedAsxl_ww_GCZZ01PMID:27034770
Currie et al., 2016		whole organism asexual adult RNA-sequencing evidence
pharynxSMED30028995h1SMcG0022485 dd_Smed_v4_14357_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parapharyngeal regionSMED30028995h1SMcG0022485 dd_Smed_v6_14357_0_1dd_Smed_v6PMID:28171748
Stückemann et al., 2017		whole organism asexual adult RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of CRAL-TRIO domain-containing protein vs. Ensembl Human
Match: TTPAL (alpha tocopherol transfer protein like [Source:HGNC Symbol;Acc:HGNC:16114])

HSP 1 Score: 87.0409 bits (214), Expect = 3.057e-18
Identity = 68/246 (27.64%), Postives = 116/246 (47.15%), Query Frame = 3 
Query:  369 KEIHENPLQVNAHIESFRRWVL-SMPHLKCPTDSRFLLKFLRIAKYDHSKAQKRLDNFCTIRASPQGAPLYFNFSGINSTLIEKVFRAH--QNVPIGKTSGNELVILYKTQDWSNDEMSVEVLLQVIYMSFDIILSKESTQINGIISFFDLERCNRKTLEIWSDPKLLKTITRIWQDAFPIRMKGIILYKEPFLFHVILKILEFFISEKHRKRFF-QIDNTEKIFNCIPGLEDIMPIEYGGKGGNL 1094
            +E+ E P      +++ R  V    P+L    D  FLL+FLR  K+D+ +A + L N+ + R S    P  FN   +  + ++ V  +     +P     G  +V + +   W      +   ++ IY++ + ++  E TQ+NGI+   D +  +      +  P + K +  I QD FPIR+K + +  EP +F  I  I++ F+ EK   RFF    +   +   +P    I+P EYGG  G L
Sbjct:   45 EELQEKPEWRLRDVQALRDMVRKEYPNLSTSLDDAFLLRFLRARKFDYDRALQLLVNYHSCRRS---WPEVFN--NLKPSALKDVLASGFLTVLPHTDPRGCHVVCI-RPDRWIPSNYPITENIRAIYLTLEKLIQSEETQVNGIVILADYKGVSLSKASHFG-PFIAKKVIGILQDGFPIRIKAVHVVNEPRIFKGIFAIIKPFLKEKIANRFFLHGSDLNSLHTNLP--RSILPKEYGGTAGEL 281
[Close]
BLAST of CRAL-TRIO domain-containing protein vs. Ensembl Human
Match: TTPAL (alpha tocopherol transfer protein like [Source:HGNC Symbol;Acc:HGNC:16114])

HSP 1 Score: 87.0409 bits (214), Expect = 3.057e-18
Identity = 68/246 (27.64%), Postives = 116/246 (47.15%), Query Frame = 3 
Query:  369 KEIHENPLQVNAHIESFRRWVL-SMPHLKCPTDSRFLLKFLRIAKYDHSKAQKRLDNFCTIRASPQGAPLYFNFSGINSTLIEKVFRAH--QNVPIGKTSGNELVILYKTQDWSNDEMSVEVLLQVIYMSFDIILSKESTQINGIISFFDLERCNRKTLEIWSDPKLLKTITRIWQDAFPIRMKGIILYKEPFLFHVILKILEFFISEKHRKRFF-QIDNTEKIFNCIPGLEDIMPIEYGGKGGNL 1094
            +E+ E P      +++ R  V    P+L    D  FLL+FLR  K+D+ +A + L N+ + R S    P  FN   +  + ++ V  +     +P     G  +V + +   W      +   ++ IY++ + ++  E TQ+NGI+   D +  +      +  P + K +  I QD FPIR+K + +  EP +F  I  I++ F+ EK   RFF    +   +   +P    I+P EYGG  G L
Sbjct:   45 EELQEKPEWRLRDVQALRDMVRKEYPNLSTSLDDAFLLRFLRARKFDYDRALQLLVNYHSCRRS---WPEVFN--NLKPSALKDVLASGFLTVLPHTDPRGCHVVCI-RPDRWIPSNYPITENIRAIYLTLEKLIQSEETQVNGIVILADYKGVSLSKASHFG-PFIAKKVIGILQDGFPIRIKAVHVVNEPRIFKGIFAIIKPFLKEKIANRFFLHGSDLNSLHTNLP--RSILPKEYGGTAGEL 281
[Close]
BLAST of CRAL-TRIO domain-containing protein vs. Ensembl Human
Match: TTPA (alpha tocopherol transfer protein [Source:HGNC Symbol;Acc:HGNC:12404])

HSP 1 Score: 84.7297 bits (208), Expect = 8.659e-18
Identity = 61/225 (27.11%), Postives = 110/225 (48.89%), Query Frame = 3 
Query:  435 SMPHLKCPTDSRFLLKFLRIAKYDHSKAQKRLDNFCTIRA-SPQ-GAPLYFNFSGINSTLIEKVFRAHQNVPIGKTSGNELVILYKTQDWSNDEMSVEVLLQVIYMSFDIILSKESTQINGIISFFDLERCN-RKTLEIWSDPKLLKTITRIWQDAFPIRMKGIILYKEPFLFHVILKILEFFISEKHRKRFFQIDNTEKIFNCIPGLEDIMPIEYGGKGGNLSD 1100
             +P    P    FLL+FLR   +D   A + L N+   RA  P+  A L+        ++I  +   +  V   +      V++Y+   W     +   + +V  ++ ++I+ +  TQ NGI + FDLE        +I   P + K I  +  D+FP++++GI L  EP +FH +  +++ F++EK ++R     N  K  + +    DI+P+EYGG+  ++ D
Sbjct:   39 GVPLAPLPLTDSFLLRFLRARDFDLDLAWRLLKNYYKWRAECPEISADLH------PRSIIGLLKAGYHGVLRSRDPTGSKVLIYRIAHWDPKVFTAYDVFRVSLITSELIVQEVETQRNGIKAIFDLEGWQFSHAFQI--TPSVAKKIAAVLTDSFPLKVRGIHLINEPVIFHAVFSMIKPFLTEKIKERIHMHGNNYKQ-SLLQHFPDILPLEYGGEEFSMED 254
[Close]
BLAST of CRAL-TRIO domain-containing protein vs. Ensembl Human
Match: CLVS2 (clavesin 2 [Source:HGNC Symbol;Acc:HGNC:23046])

HSP 1 Score: 84.7297 bits (208), Expect = 1.817e-17
Identity = 69/294 (23.47%), Postives = 130/294 (44.22%), Query Frame = 3 
Query:  324 YFYKNLSSRDQEILSKEIHENPLQVNAHIESFRRWVLSMPHLK-CPTDSRFLLKFLRIAKYDHSKAQKRLDNFCTIRASPQGAPLYFNFSGINSTLIEKVFRAHQNVPIGKTS----GNELVILYKTQDWSNDEMSVEVLLQVIYMSFDIILSKESTQINGIISFFDLERCNRKTLEIWSDPKLLKTITRIWQDAFPIRMKGIILYKEPFLFHVILKILEFFISEKHRKRFFQIDNTEKIFNCIPGL--EDIMPIEYGGKGGNLSDKVDLFYLENWIKEVKDFHSNRDSWWNFE 1184
            +    LS    E    E++ENP  ++  I+  R  V++ P +    TD  F+L+FLR  K+ H +A + L  +   R   Q   ++ +F   +  + + +       P G  +    G ++++L+   +W     ++  +L+ I +S + ++     Q+NG +   D      K     + P +L+      QD+FP R  GI    +P+  H +  ++  F+ EK RKR F   N     N +  L   +I+P E+GG        +  + +  W + + D   + DS +N +
Sbjct:    3 HLQAGLSPETLEKARLELNENPDTLHQDIQEVRDMVITRPDIGFLRTDDAFILRFLRARKFHHFEAFRLLAQYFEYRQ--QNLDMFKSFKATDPGIKQAL---KDGFPGGLANLDHYGRKILVLFAA-NWDQSRYTLVDILRAILLSLEAMIEDPELQVNGFVLIIDWSNFTFKQASKLT-PSMLRLAIEGLQDSFPARFGGIHFVNQPWYIHALYTVIRPFLKEKTRKRIFLHGNN---LNSLHQLIHPEILPSEFGG-------MLPPYDMGTWARTLLDHEYDDDSEYNVD 279
[Close]
BLAST of CRAL-TRIO domain-containing protein vs. Ensembl Human
Match: CLVS1 (clavesin 1 [Source:HGNC Symbol;Acc:HGNC:23139])

HSP 1 Score: 78.5666 bits (192), Expect = 2.541e-15
Identity = 60/254 (23.62%), Postives = 110/254 (43.31%), Query Frame = 3 
Query:  324 YFYKNLSSRDQEILSKEIHENPLQVNAHIESFRRWVLSMPHLK-CPTDSRFLLKFLRIAKYDHSKAQKRLDNFCTIRASPQGAPLYFNFSGINSTLIEKVFRAHQNVPIGKTSGNELVILYKTQDWSNDEMSVEVLLQVIYMSFDIILSKESTQINGIISFFDLERCNRKTLEIWSDPKLLKTITRIWQDAFPIRMKGIILYKEPFLFHVILKILEFFISEKHRKR-FFQIDNTEKIFNCIPGLEDIMPIEYGG 1079
            +    LS    E    E++ENP  ++  I+  R  +++ P +    TD  F+L+FLR  K+  + A + L  +   R       ++ NF   +  +   +      V   +      ++L    +W     S   +L+ I +S ++++     QING I   D    + K     + P +LK      QD+FP R  G+    +P+  H +  +++ F+ +K RKR F   +N   +   I    + +P E+GG
Sbjct:   25 HLQAGLSPETIEKARLELNENPDVLHQDIQQVRDMIITRPDIGFLRTDDAFILRFLRARKFHQADAFRLLAQYFQYRQ--LNLDMFKNFKADDPGIKRALIDGFPGVLENRDHYGRKILLLFAANWDQSRNSFTDILRAILLSLEVLIEDPELQINGFILIIDWSNFSFKQASKLT-PSILKLAIEGLQDSFPARFGGVHFVNQPWYIHALYTLIKPFLKDKTRKRIFLHGNNLNSLHQLIH--PEFLPSEFGG 273
[Close]
BLAST of CRAL-TRIO domain-containing protein vs. Ensembl Fly
Match: CG33966 (gene:FBgn0053966 transcript:FBtr0100007)

HSP 1 Score: 95.1301 bits (235), Expect = 1.848e-21
Identity = 76/321 (23.68%), Postives = 150/321 (46.73%), Query Frame = 3 
Query:  333 KNLSSRDQEILSKEIHENPLQVNAHIESFRRWVLSMPHLKCPTDSRFLLKFLRIAKYDHSKAQKRLDNFCTIRASPQGAPLYFNFSGINSTLIEKVFRAHQNVPIGKT---SGNELVILYKTQDWSNDEMSVEVLLQVIYMSFDIILSKESTQI-NGIISFFDLERCNRKTLEIWSDPKLLKTITRIWQDAFPIRMKGIILYKEPFLFHVILKILEFFISEKHRKRFFQIDNT-EKIFNCIPGLEDIMPIEYGGKGGNLSDKVDLFYLENWIKEVKDFHSNRDSWWNFEVDEKKRQPDTKNFLKNYEDYVGETICGTPGSF 1280
            + LS   Q+   + ++E P +++  I + R W+   PHLK  TD +FL+ FLR  K+   + + ++D F T+R      P ++    ++     ++FR    V + +    +G  L +L +   +   + +++ + +   +   I+L ++   I NG+IS  DL         +   P   K +T   ++A P+R +GI     P  F  I  +++  +S+K + R +   +  E ++N IP  +  +P+EYGG+ G++ +      L+ W + +  + +  +   N+  DE  R     +F         E++ G  GSF
Sbjct:    5 RPLSPELQKTAIENLNEVPNKLDDDIAALRDWIKQQPHLKARTDDQFLVNFLRGCKFSLERTKSKIDRFYTLRTK---YPEFYLGHNVDVDKALEIFRLGTIVILPRPLNDNGPRLALL-RMACYDPSKYTLQEVNRAAGLMQQIMLDEDDVAIVNGLISILDLSNVTTGHF-LQMSPSFAKKMTVFQEEALPLRPQGIHFINTPNGFDTIFNMIKPMMSKKQQGRLYVHGSKWEALYNQIP--KQYLPVEYGGENGSIPE-----LLQQWEQRILAYRNYWEEEKNYGTDESLRVGQPVDF---------ESLFGLQGSF 304
[Close]
BLAST of CRAL-TRIO domain-containing protein vs. Ensembl Fly
Match: CG31636 (gene:FBgn0051636 transcript:FBtr0079324)

HSP 1 Score: 94.7449 bits (234), Expect = 2.483e-21
Identity = 72/285 (25.26%), Postives = 127/285 (44.56%), Query Frame = 3 
Query:  333 KNLSSRDQEILSKEIHENPLQVNAHIESFRRWVLSMPHLKCPTDSRFLLKFLRIAKYDHSKAQKRLDNFCTIRASPQGAPLYFNFSGINS-TLIEKVFRAHQ--NVPIGKTSGNELVILYKTQDWSNDEMSVEVLLQVIYMSFDIIL-SKESTQINGIISFFDLERCNRKTLEIWSDPKLLKTITRIWQDAFPIRMKGIILYKEPFLFHVILKILEFFISEKHRKRFFQIDNTEKIFNCIPGLEDIMPIEYGGKGGNLSD-----KVDLFYLENWIKEVKDFHSN 1160
            + L++  QEI  +E++E P ++   IE+ R WVL  PHL+  TD +FLL FLR  K+   +A+++ D F T++ S    P  FN   + +   +  + R      +P+        V + +   +   +   + +++V  M  +I++   ++  ++G +   D+       L     P+LL   +    +A P R KGI     P  F      L  F   K + R     +   I+  +      +P EYGG GGNL D     +  L     + +E ++F +N
Sbjct:    5 RPLNAALQEICIRELNELPARMAQDIEALRDWVLKQPHLRACTDDQFLLAFLRGTKFSLERAKEKFDRFYTLQRS---IPEVFNERRLATDPQVLDIVRMGVLLQIPMDADDPGPRVTIIRAGSYDTSKHKFQDIIRVGSMFGEIMMFEDDNATVSGYVEIMDMAGVTGSHL-FALQPQLLSKFSTYADEAMPTRQKGIHFINVPAAFETGFNSLRSFFPAKIKSRISVSSDPAAIYELV--RRKYLPQEYGGTGGNLQDISHTMEAKLSSYGPYFRESQNFGAN 283
[Close]
BLAST of CRAL-TRIO domain-containing protein vs. Ensembl Fly
Match: CG31636 (gene:FBgn0051636 transcript:FBtr0343865)

HSP 1 Score: 94.7449 bits (234), Expect = 2.483e-21
Identity = 72/285 (25.26%), Postives = 127/285 (44.56%), Query Frame = 3 
Query:  333 KNLSSRDQEILSKEIHENPLQVNAHIESFRRWVLSMPHLKCPTDSRFLLKFLRIAKYDHSKAQKRLDNFCTIRASPQGAPLYFNFSGINS-TLIEKVFRAHQ--NVPIGKTSGNELVILYKTQDWSNDEMSVEVLLQVIYMSFDIIL-SKESTQINGIISFFDLERCNRKTLEIWSDPKLLKTITRIWQDAFPIRMKGIILYKEPFLFHVILKILEFFISEKHRKRFFQIDNTEKIFNCIPGLEDIMPIEYGGKGGNLSD-----KVDLFYLENWIKEVKDFHSN 1160
            + L++  QEI  +E++E P ++   IE+ R WVL  PHL+  TD +FLL FLR  K+   +A+++ D F T++ S    P  FN   + +   +  + R      +P+        V + +   +   +   + +++V  M  +I++   ++  ++G +   D+       L     P+LL   +    +A P R KGI     P  F      L  F   K + R     +   I+  +      +P EYGG GGNL D     +  L     + +E ++F +N
Sbjct:    5 RPLNAALQEICIRELNELPARMAQDIEALRDWVLKQPHLRACTDDQFLLAFLRGTKFSLERAKEKFDRFYTLQRS---IPEVFNERRLATDPQVLDIVRMGVLLQIPMDADDPGPRVTIIRAGSYDTSKHKFQDIIRVGSMFGEIMMFEDDNATVSGYVEIMDMAGVTGSHL-FALQPQLLSKFSTYADEAMPTRQKGIHFINVPAAFETGFNSLRSFFPAKIKSRISVSSDPAAIYELV--RRKYLPQEYGGTGGNLQDISHTMEAKLSSYGPYFRESQNFGAN 283
[Close]
BLAST of CRAL-TRIO domain-containing protein vs. Ensembl Fly
Match: CG12926 (gene:FBgn0033437 transcript:FBtr0088502)

HSP 1 Score: 90.1225 bits (222), Expect = 1.006e-19
Identity = 78/307 (25.41%), Postives = 135/307 (43.97%), Query Frame = 3 
Query:  372 EIHENPLQVNAHIESFRRWVLSMPHLKCPTDSRFLLKFLRIAKYDHSKAQKRLDNFCTIR-ASPQGAPLYFNFSGINSTLIEKVFRAHQNVPIGKTSGNELVILYKTQDWSNDEMSVEVLLQVIYMSFDI-ILSKESTQINGIISFFDLERCNRKTLEIWSDPKLLKTITRIWQDAFPIRMKGIILYKEPFLFHVILKILEFFISEKHRKRFFQIDNTEKIFNCIPGLEDIMPIEYGGKGGNLSDKVDLFYLENWIKEVKDFHSNRDSWWNFEVDEKKRQPDTKNFLKNYEDYVGETICGTPGSFIK 1286
            E+ E P +++  IE+ R W+   PHLK   D++FL+ FLR  KY   K + +LDNF  +R A P+   LY N       L          +P    +    + + +   + + + S+  ++QV  M  +I I   ++  I+G +   D++      L    D  L+K +  +   A+P R KG      P      + I +  +SEK RKRF      + ++  +P  ++ +P EYGG  G + D V       W  ++  +    +   ++  +EK         L+  +    E++ G  GSF K
Sbjct:   23 ELGEIPDRIDEDIETLRTWISKQPHLKARQDAQFLVAFLRGCKYSLEKTKLKLDNFYAMRGAVPE---LYKNRIVGEKQLSILDTGCLLRLPQPLQADGPRIHISRYGQYDSKKYSIAEVVQVNTMLGEIQIREDDNAMISGFVEIIDMKGVGAGHL-FQFDAVLVKKLAVLGDKAYPYRPKGFHFVNAPSSAEKFMSIAKSLMSEKIRKRFHIHSKLDSLYKYVP--KECLPAEYGGSNGTIQDVVS-----TWRTKLLAYKPFFEEEASYGTNEK---------LRRGQPVSAESLFGIEGSFRK 309
[Close]
BLAST of CRAL-TRIO domain-containing protein vs. Ensembl Fly
Match: CG2663 (gene:FBgn0037323 transcript:FBtr0078795)

HSP 1 Score: 86.2705 bits (212), Expect = 2.219e-18
Identity = 69/266 (25.94%), Postives = 116/266 (43.61%), Query Frame = 3 
Query:  381 ENPLQVNAHIESFRRWVLSMPHLKCPTDSRFLLKFLRIAKYDHSKAQKRLDNFCTIRASPQGAPLYFNFSGINSTLIEKVFR-AHQNVPIGKTSGNELVILYKTQDWSNDEMSVEVLLQVIYMSFDIILSKESTQINGIISFFDLERCNRKTLEIWSDPKLLKTITRIWQDAFPIRMKGIILYKEPFLFHVILKILEFFISEKHRKRFFQIDNTEKIFNCIPGLEDIMPIEYGGKGGNLSD-----KVDLFYLENWIKEVKDFHSN 1160
            E+P  +   I+  R W+ + PHL    D   L  FLR  K+   K +K+LD + T+R      P +F+   IN   +  V    H     G T     +   +  D       +   ++V  M  D+ L++ES  I G I   D    +      +S P ++K      Q+A+P+++K + +     L   I   ++ F+ EK R R    ++ E ++  +P   D++P EYGGK G + +     K  L     W K+ +D  +N
Sbjct:   22 EDPADIERDIKLIREWLETQPHLPKDMDDMRLTTFLRGCKFSLEKVKKKLDMYYTMR---NAVPEFFSNRDINREELNIVLDYVHCPTLPGITPNGRRITFIRGIDCDFQPHHILDAMKVALMIGDVRLAEESVGIAGDIFILDASVASAAHFAKFS-PTVVKKFLIAVQEAYPVKVKEVHVINISPLVDTIFNFVKPFVKEKIRSRITFHNDVESLYKVVP--RDLLPNEYGGKAGGVVELNQWWKQKLVDNTQWFKDQEDKKAN 281
[Close]
BLAST of CRAL-TRIO domain-containing protein vs. Ensembl Zebrafish
Match: ttpal (tocopherol (alpha) transfer protein-like [Source:ZFIN;Acc:ZDB-GENE-030131-296])

HSP 1 Score: 86.2705 bits (212), Expect = 3.441e-18
Identity = 67/249 (26.91%), Postives = 119/249 (47.79%), Query Frame = 3 
Query:  369 KEIHENPLQVNAHIESFRRWVL-SMPHLKCPTDSRFLLKFLRIAKYDHSKAQKRLDNF-CTIRASPQGAPLYFNFSGINSTLIEKVFRAH--QNVPIGKTSGNELVILYKTQDWSNDEMSVEVLLQVIYMSFDIILSKESTQINGIISFFDLERCNRKTLEIWSDPK--LLKTITRIWQDAFPIRMKGIILYKEPFLFHVILKILEFFISEKHRKRF-FQIDNTEKIFNCIPGLEDIMPIEYGGKGGNL 1094
            +E+ E P      +++ R  +L   P+L+   D  FLL+FLR  K+D+ +A + L N+  + RA P+       F  +  + ++ V        +P     G  ++ L +   W  ++      ++ IY++ + ++  E TQ+NG++   D        L   S+P   L K +  I QD FPIR+K + +  EP +F  I  I++ F+ EK  +R+     +   +   IP  + ++P EYGG  G L
Sbjct:   44 EELQEKPEWRLRDVQALRDMILKDHPNLRTRLDDAFLLRFLRARKFDYDRALQLLLNYHASRRAWPE------VFQDLKPSTVKHVLDLGFLTVLPRPDPQGRYILCL-RPGKWKPNDYPFVDNIRAIYLTLEKLIQPEETQVNGVVILVDYAGVG---LSQASNPGPLLAKKVVGILQDGFPIRIKAVNIINEPRIFKGIFAIIKPFLKEKMAERYVLHGSDLASLHRVIP--QSVLPQEYGGVSGRL 280
[Close]
BLAST of CRAL-TRIO domain-containing protein vs. Ensembl Zebrafish
Match: ttpal (tocopherol (alpha) transfer protein-like [Source:ZFIN;Acc:ZDB-GENE-030131-296])

HSP 1 Score: 83.9593 bits (206), Expect = 9.807e-18
Identity = 60/222 (27.03%), Postives = 105/222 (47.30%), Query Frame = 3 
Query:  441 PHLKCPTDSRFLLKFLRIAKYDHSKAQKRLDNF-CTIRASPQGAPLYFNFSGINSTLIEKVFRAH--QNVPIGKTSGNELVILYKTQDWSNDEMSVEVLLQVIYMSFDIILSKESTQINGIISFFDLERCNRKTLEIWSDPKLLKTITRIWQDAFPIRMKGIILYKEPFLFHVILKILEFFISEKHRKRF-FQIDNTEKIFNCIPGLEDIMPIEYGGKGGNL 1094
            P+L+   D  FLL+FLR  K+D+ +A + L N+  + RA P+       F  +  + ++ V        +P     G  ++ L +   W  ++      ++ IY++ + ++  E TQ+NG++   D              P L K +  I QD FPIR+K + +  EP +F  I  I++ F+ EK  +R+     +   +   IP  + ++P EYGG  G L
Sbjct:    7 PNLRTRLDDAFLLRFLRARKFDYDRALQLLLNYHASRRAWPE------VFQDLKPSTVKHVLDLGFLTVLPRPDPQGRYILCL-RPGKWKPNDYPFVDNIRAIYLTLEKLIQPEETQVNGVVILVDYAGVGLSQAS-NPGPLLAKKVVGILQDGFPIRIKAVNIINEPRIFKGIFAIIKPFLKEKMAERYVLHGSDLASLHRVIP--QSVLPQEYGGVSGRL 218
[Close]
BLAST of CRAL-TRIO domain-containing protein vs. Ensembl Zebrafish
Match: clvs2 (clavesin 2 [Source:NCBI gene;Acc:566769])

HSP 1 Score: 82.8037 bits (203), Expect = 5.489e-17
Identity = 67/267 (25.09%), Postives = 116/267 (43.45%), Query Frame = 3 
Query:  324 YFYKNLSSRDQEILSKEIHENPLQVNAHIESFRRWVLSMPHLK-CPTDSRFLLKFLRIAKYDHSKA-----------QKRLDNFCTIRASPQG--APLYFNFSGINSTLIEKVFRAHQNVPIGKTSGNELVILYKTQDWSNDEMSVEVLLQVIYMSFDIILSKESTQINGIISFFDLERCNRKTLEIWSDPKLLKTITRIWQDAFPIRMKGIILYKEPFLFHVILKILEFFISEKHRKR-FFQIDNTEKIFNCIPGLEDIMPIEYGG 1079
            +    LS    E    E+ ENP  ++  I+  R  +++ P +    TD  F+L+FLR  K++H +A           Q+ LD F  ++A+  G    L   F G+ S L                 G ++++L+   +W     +   +L+ I +S + ++     Q+NG +   D      K     + P +L+      QD+FP R  GI    +P+  H +  ++  F+ +K RKR F   +N   +   I  L +I+P E GG
Sbjct:    3 HLQAGLSPETLEKAKVELKENPDTLHQDIQEVRDMIITRPDIGFLRTDDAFILRFLRARKFNHFEAFRLLAQYFEYRQQNLDMFKNLKATDPGIKQALKDGFPGVLSNL--------------DRYGRKILVLFAA-NWDQSRYTFVDILRAILLSLEAMIEDPELQVNGFVLIIDWSNFTFKQASKLT-PSMLRLAIEGLQDSFPARFGGIHFVNQPWYIHALYTVIRPFLKDKTRKRIFMHGNNLNSLHQLI--LPEILPSELGG 251
[Close]
BLAST of CRAL-TRIO domain-containing protein vs. Ensembl Zebrafish
Match: ttpa (tocopherol (alpha) transfer protein [Source:ZFIN;Acc:ZDB-GENE-030131-4631])

HSP 1 Score: 72.7886 bits (177), Expect = 6.492e-14
Identity = 54/213 (25.35%), Postives = 104/213 (48.83%), Query Frame = 3 
Query:  471 FLLKFLRIAKYDHSKAQKRLDNFCTIRASPQGAPLYFNFSGINSTLIEKVFRAHQNVPIGKTSGNELVILYKTQDWSNDEMSVEVLLQVIYMSFDIILSKESTQINGIISFFDLER-CNRKTLEIWSDPKLLKTITRIWQDAFPIRMKGIILYKEPFLFHVILKILEFFISEKHRKRFFQ--IDNTEKIFNCIPGLEDIMPIEYGGKGGNLSD 1100
            FL++FL+   +D + A K L N+   R   Q  P         S++I  +   +  V   +      V++Y+   W+  E +   + +V  ++ ++I+ +  TQ NG+ + FDL+  C    L+I  +P L K I+ +  D+FP++++GI L  EP  F  +  ++  F+ +K ++R           + N  P  + ++P  YGG G ++ +
Sbjct:   48 FLIRFLQARDFDVALALKLLINYHKWR---QECP-EITADLRPSSVIGLLQNNYHGVLRSRDDAGSRVLIYRIGKWNPKEFTAYEVFRVSLITSELIVQEWETQRNGLKAIFDLQDWCFAHALQI--NPSLAKKISSVLTDSFPLKVRGIHLINEPIFFRPVFAMIRPFLPDKIKQRIHMHGCSYARSLCNYFP--KAVLPPVYGGTGPSVDE 252
[Close]
BLAST of CRAL-TRIO domain-containing protein vs. Ensembl Zebrafish
Match: rlbp1b (retinaldehyde binding protein 1b [Source:ZFIN;Acc:ZDB-GENE-040426-1870])

HSP 1 Score: 62.3882 bits (150), Expect = 2.867e-10
Identity = 53/222 (23.87%), Postives = 104/222 (46.85%), Query Frame = 3 
Query:  474 LLKFLRIAKYDHSKAQKRLDNFCTIRAS-PQGAPLYFNFS--GINSTLIEKVFRAHQNVPIGKTSGNELVILYKTQDWSNDEMSVEVLLQVIYMSFDIILSKESTQINGIISFFDLERCNRKTLEIWSD--PKLLKTITRIWQDAFPIRMKGIILYKEPFLFHVILKILEFFISEKHRKR-FFQIDNTEKIFNCIPGLEDIMPIEYGGKGGNLSDKVDLFYL 1121
            L++F+R  KYD ++A + +  +   R   P+   L+ N +   + ST    +   +  +   +     +V+L+  ++W  +E++ + +L+   +  + +L  E TQING   F  +E     T++  S   P  LK +  + QD+FP R K +    +P+ F     +++  +  K  +R F   D+ E  F       +I+P ++ GKG     K+   +L
Sbjct:   96 LVRFIRARKYDVNRAYELMKGYVRFRRDYPE---LFENLTPEAVRST----IEAGYPGILSSRDKYGRVVLLFNIENWDYEEITFDEILRAYCVILEKLLENEETQING---FCIIENFKGFTMQQASGIKPTELKKMVDMLQDSFPARFKAVHFIHQPWYFTTTYNVVKPLMKSKLLERVFVHGDDLENYFKEFDA--EILPSDFDGKGSKYDGKITAAHL 305
[Close]
BLAST of CRAL-TRIO domain-containing protein vs. Ensembl Xenopus
Match: ttpal (tocopherol (alpha) transfer protein-like [Source:NCBI gene;Acc:548930])

HSP 1 Score: 98.5969 bits (244), Expect = 3.395e-22
Identity = 83/293 (28.33%), Postives = 135/293 (46.08%), Query Frame = 3 
Query:  369 KEIHENPLQVNAHIESFRRWVL-SMPHLKCPTDSRFLLKFLRIAKYDHSKAQKRLDNFCTIR-ASPQGAPLYFNFSGINSTLIEKVFRAH--QNVPIGKTSGNELVILYKTQDWSNDEMSVEVLLQVIYMSFDIILSKESTQINGIISFFDLERCNRKTLEIWSDPKLLKTITRIWQDAFPIRMKGIILYKEPFLFHVILKILEFFISEKHRKRFF-QIDNTEKIFNCIPGLEDIMPIEYGGKGGNLSDKVDLFYLENWIKEVKDFHSNRDSWWNFEVDEKKRQPDTKNFLKN 1232
            +E+ E P      +++ R  V    PHLK   D  FLL+FLR  K+D+ +A + L N+ + R A P+       F+ +  + ++ V  +     +P   T G  +V + +   W   +  +   ++ IY+S + ++  E TQ+NGI+   D           +  P + K +  I QD FPIR+K + +  EP +F  I  IL+ F+ EK  KRFF    +   +   IP  + I+P EYGG  G L           W + + D  S  D   +F +    R+   + FL N
Sbjct:   42 EELQEKPEWRLRDVQALRDMVWKDYPHLKTRVDDSFLLRFLRARKFDYDRALQLLVNYYSCRKAWPE------VFTDLRPSAVKPVLDSGFLTVLPHTDTEGRRIVCI-RPGCWIPRDYPITENIRAIYLSLEKLVESEETQVNGIVILADYNGVGLTHASHFG-PFIAKKVIGILQDGFPIRIKAVNVINEPRIFKGIFAILKPFLKEKIVKRFFLHGSDLNSLHANIP--KSILPEEYGGTAGKLDTTA-------WSQILLD--SEEDFAVHFGLAHPTREGSLQGFLMN 315
[Close]
BLAST of CRAL-TRIO domain-containing protein vs. Ensembl Xenopus
Match: thg1l (tRNA-histidine guanylyltransferase 1-like [Source:Xenbase;Acc:XB-GENE-966760])

HSP 1 Score: 85.5001 bits (210), Expect = 9.465e-18
Identity = 74/303 (24.42%), Postives = 130/303 (42.90%), Query Frame = 3 
Query:  324 YFYKNLSSRDQEILSKEIHENPLQVNAHIESFRRWVLSMPHLK-CPTDSRFLLKFLRIAKYDHSKA-----------QKRLDNFCTIRASPQG--APLYFNFSGINSTLIEKVFRAHQNVPIGKTSGNELVILYKTQDWSNDEMSVEVLLQVIYMSFDIILSKESTQINGIISFFDLERCNRKTLEIWSDPKLLKTITRIWQDAFPIRMKGIILYKEPFLFHVILKILEFFISEKHRKRFFQIDNTEKIFNCIPGL--EDIMPIEYGGKGGNLSDKVDLFYLENWIKEVKDFHSNRDSWWNFE 1184
            +    LS    E    E++ENP  ++  I+  R  V++ P +    TD  F+L+FLR  K++H +A           Q+ LD F   +A+  G    L   F G+ S L                 G ++++L+   +W     ++  +L+ I +S + ++     Q+NG +   D      K     + P +L+      QD+FP R  GI    +P+  H +  ++  F+ EK RKR F   N     N +  L   +I+P E+GG        +  + +  W + + D   + +S +N E
Sbjct:    3 HLQAGLSPETLEKARLELNENPDTLHQDIQEVRDMVITRPDIGFLRTDDAFILRFLRARKFNHFEAFRLLAQYFEYRQQNLDMFKNFKATDPGIKQGLKDGFPGVLSNL--------------DHFGRKILVLFAA-NWDQSRYTLVDILRAILLSLEAMIEDPELQVNGFVLIIDWSNFTFKQASKLT-PSMLRLAIEGLQDSFPARFGGIHFVNQPWYIHALYTVIRPFLKEKTRKRIFLHGNN---LNSLHQLIHPEILPSEFGG-------MLPPYDMGTWARTLLDHEYDDESEYNVE 279
[Close]
BLAST of CRAL-TRIO domain-containing protein vs. Ensembl Xenopus
Match: clvs1 (clavesin 1 [Source:NCBI gene;Acc:100037913])

HSP 1 Score: 81.2629 bits (199), Expect = 2.104e-16
Identity = 69/274 (25.18%), Postives = 121/274 (44.16%), Query Frame = 3 
Query:  303 IERMADYYFYKNLSSRDQEILSKEIHENPLQVNAHIESFRRWVLSMPHLK-CPTDSRFLLKFLRIAKYDHSKA-----------QKRLDNFCTIRASPQGA--PLYFNFSGINSTLIEKVFRAHQNVPIGKTSGNELVILYKTQDWSNDEMSVEVLLQVIYMSFDIILSKESTQINGIISFFDLERCNRKTLEIWSDPKLLKTITRIWQDAFPIRMKGIILYKEPFLFHVILKILEFFISEKHRKR-FFQIDNTEKIFNCIPGLEDIMPIEYGG 1079
            +E +   + +  LS    E    E++ENP  ++  I+  R  +++ P +    TD  F+L+FLR  K++  +A           Q  LD F  ++A   G    L   F G+         R H         G ++++L+   +W     S   +L+ I +S ++++  +  QING I   D    + K     + P +L+      QD+FP R  G+    +P+  H +  I++ F+ +K RKR F   +N   +   I    D +P E+GG
Sbjct:   15 VEDLKMTHLHAGLSPETIEKSRLELNENPDTLHQDIQQVRDMIITRPDIGFLRTDDAFILRFLRARKFNQMEAFRLLAQYFQYRQLNLDMFKNLKADDPGIKRALMDGFPGVLEN------RDHY--------GRKILLLFAA-NWDQSRNSFVDILRAILLSLEVLIEDQELQINGFILIIDWSNFSFKQASKLT-PSILRLAIEGLQDSFPARFGGVHFVNQPWYIHALYTIIKPFLKDKTRKRIFLHGNNLNSLHQLIH--PDCLPSEFGG 270
[Close]
BLAST of CRAL-TRIO domain-containing protein vs. Ensembl Xenopus
Match: clvs1 (clavesin 1 [Source:NCBI gene;Acc:100037913])

HSP 1 Score: 80.1073 bits (196), Expect = 6.749e-16
Identity = 68/267 (25.47%), Postives = 118/267 (44.19%), Query Frame = 3 
Query:  324 YFYKNLSSRDQEILSKEIHENPLQVNAHIESFRRWVLSMPHLK-CPTDSRFLLKFLRIAKYDHSKA-----------QKRLDNFCTIRASPQGA--PLYFNFSGINSTLIEKVFRAHQNVPIGKTSGNELVILYKTQDWSNDEMSVEVLLQVIYMSFDIILSKESTQINGIISFFDLERCNRKTLEIWSDPKLLKTITRIWQDAFPIRMKGIILYKEPFLFHVILKILEFFISEKHRKR-FFQIDNTEKIFNCIPGLEDIMPIEYGG 1079
            + +  LS    E    E++ENP  ++  I+  R  +++ P +    TD  F+L+FLR  K++  +A           Q  LD F  ++A   G    L   F G+         R H         G ++++L+   +W     S   +L+ I +S ++++  +  QING I   D    + K     + P +L+      QD+FP R  G+    +P+  H +  I++ F+ +K RKR F   +N   +   I    D +P E+GG
Sbjct:    3 HLHAGLSPETIEKSRLELNENPDTLHQDIQQVRDMIITRPDIGFLRTDDAFILRFLRARKFNQMEAFRLLAQYFQYRQLNLDMFKNLKADDPGIKRALMDGFPGVLEN------RDHY--------GRKILLLFAA-NWDQSRNSFVDILRAILLSLEVLIEDQELQINGFILIIDWSNFSFKQASKLT-PSILRLAIEGLQDSFPARFGGVHFVNQPWYIHALYTIIKPFLKDKTRKRIFLHGNNLNSLHQLIH--PDCLPSEFGG 251
[Close]
BLAST of CRAL-TRIO domain-containing protein vs. Ensembl Xenopus
Match: ggh (gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) [Source:NCBI gene;Acc:594986])

HSP 1 Score: 78.1814 bits (191), Expect = 1.593e-15
Identity = 60/217 (27.65%), Postives = 104/217 (47.93%), Query Frame = 3 
Query:  471 FLLKFLRIAKYDHSKAQKRLDNFCTIRA-SPQGAPLYFNFSGINSTLIEKVFRA-HQNVPIGKTSGNELVILYKTQDWSNDEMSVEVLLQVIYMSFDIILSKESTQINGIISFFDLERCNRKTLEIWSDPKLLKTITRIWQDAFPIRMKGIILYKEPFLFHVILKILEFFISEKHRKRFFQIDNTEKIFNCIPGL-----EDIMPIEYGGKGGNLSD 1100
            FLL+FLR   +    A K L N+   RA  P+        + +  + I  +FRA +  V   +      V++Y+ + W     +   + +V  ++ ++I+ +  TQ NGI + FDL+   R        P + K I  +  D+FP++++G+ L  EP  FH +  I++ F+ +K ++R     +     N IP L       I+P EYGG G  +S+
Sbjct:   51 FLLRFLRARDFCIELAFKLLKNYHKWRAECPEIT------ADLRPSPILDLFRAGYHAVLRSRDDSGSKVLIYRIEYWDPKLFTAYEVFRVSLITSELIVQEAETQRNGIKAIFDLQGW-RLAHAFQITPTMAKRIAAVMADSFPLKVRGVHLINEPLFFHPVFAIIKPFLPDKIKQRVHMHGS-----NYIPTLNQHFSTSILPPEYGGTGPAMSE 255
[Close]
BLAST of CRAL-TRIO domain-containing protein vs. Ensembl Mouse
Match: Ttpal (tocopherol (alpha) transfer protein-like [Source:MGI Symbol;Acc:MGI:1923330])

HSP 1 Score: 88.9669 bits (219), Expect = 6.081e-19
Identity = 72/266 (27.07%), Postives = 125/266 (46.99%), Query Frame = 3 
Query:  369 KEIHENPLQVNAHIESFRRWVL-SMPHLKCPTDSRFLLKFLRIAKYDHSKAQKRLDNFCTIRAS-PQGAPLYFNFSGINSTLIEKVFRAH--QNVPIGKTSGNELVILYKTQDWSNDEMSVEVLLQVIYMSFDIILSKESTQINGIISFFDLERCNRKTLEIWSDPKLLKTITRIWQDAFPIRMKGIILYKEPFLFHVILKILEFFISEKHRKRFF-QIDNTEKIFNCIPGLEDIMPIEYGGKGGNLS----DKVDLFYLENWIKE 1139
            +E+ E P      +++ R  V    P+L    D  FLL+FLR  K+D+ +A + L N+   R S P+       FS +  + ++ V  +     +P     G   V+  +   W      +   ++ +Y++ + ++  E TQ+NGI+   D +  +      +  P + K +  I QD FPIR+K + +  EP +F  I  I++ F+ EK   RFF    +   +   +P   +I+P EYGG  G L     + V L   E+++KE
Sbjct:   46 EELQEKPEWRLRDVQALRDMVRKEYPYLSTSLDDAFLLRFLRARKFDYDRALQLLVNYHGCRRSWPE------VFSNLRPSALKDVLNSGFLTVLPHTDPRGCH-VLCIRPDRWIPSNYPITENIRAVYLTLEKLIQSEETQVNGIVILADYKGVSLSKASHFG-PFIAKKVIGILQDGFPIRIKAVHIVNEPRIFKGIFAIIKPFLKEKIANRFFLHGSDLNSLHTNLP--RNILPKEYGGTAGELDTASWNAVLLASEEDFVKE 301
[Close]
BLAST of CRAL-TRIO domain-containing protein vs. Ensembl Mouse
Match: Ttpal (tocopherol (alpha) transfer protein-like [Source:MGI Symbol;Acc:MGI:1923330])

HSP 1 Score: 88.9669 bits (219), Expect = 6.081e-19
Identity = 72/266 (27.07%), Postives = 125/266 (46.99%), Query Frame = 3 
Query:  369 KEIHENPLQVNAHIESFRRWVL-SMPHLKCPTDSRFLLKFLRIAKYDHSKAQKRLDNFCTIRAS-PQGAPLYFNFSGINSTLIEKVFRAH--QNVPIGKTSGNELVILYKTQDWSNDEMSVEVLLQVIYMSFDIILSKESTQINGIISFFDLERCNRKTLEIWSDPKLLKTITRIWQDAFPIRMKGIILYKEPFLFHVILKILEFFISEKHRKRFF-QIDNTEKIFNCIPGLEDIMPIEYGGKGGNLS----DKVDLFYLENWIKE 1139
            +E+ E P      +++ R  V    P+L    D  FLL+FLR  K+D+ +A + L N+   R S P+       FS +  + ++ V  +     +P     G   V+  +   W      +   ++ +Y++ + ++  E TQ+NGI+   D +  +      +  P + K +  I QD FPIR+K + +  EP +F  I  I++ F+ EK   RFF    +   +   +P   +I+P EYGG  G L     + V L   E+++KE
Sbjct:   46 EELQEKPEWRLRDVQALRDMVRKEYPYLSTSLDDAFLLRFLRARKFDYDRALQLLVNYHGCRRSWPE------VFSNLRPSALKDVLNSGFLTVLPHTDPRGCH-VLCIRPDRWIPSNYPITENIRAVYLTLEKLIQSEETQVNGIVILADYKGVSLSKASHFG-PFIAKKVIGILQDGFPIRIKAVHIVNEPRIFKGIFAIIKPFLKEKIANRFFLHGSDLNSLHTNLP--RNILPKEYGGTAGELDTASWNAVLLASEEDFVKE 301
[Close]
BLAST of CRAL-TRIO domain-containing protein vs. Ensembl Mouse
Match: Ttpa (tocopherol (alpha) transfer protein [Source:MGI Symbol;Acc:MGI:1354168])

HSP 1 Score: 83.9593 bits (206), Expect = 1.004e-17
Identity = 67/259 (25.87%), Postives = 123/259 (47.49%), Query Frame = 3 
Query:  348 RDQEILSKEIHENPLQ---VNAHIESFRRWV--LSMPHLKCPTDSRFLLKFLRIAKYDHSKAQKRLDNFCTIRA-SPQGAPLYFNFSGINSTLIEKVFRA-HQNVPIGKTSGNELVILYKTQDWSNDEMSVEVLLQVIYMSFDIILSKESTQINGIISFFDLERCN-RKTLEIWSDPKLLKTITRIWQDAFPIRMKGIILYKEPFLFHVILKILEFFISEKHRKRFFQIDNTEKIFNCIPGLEDIMPIEYGGKGGNLSD 1100
            R   ++ K+++E P     +   +   RR V    +P    P    FLL+FLR   +D   A + + N+   RA  P+ +      + +    I  + +A +  V   + S    V++Y+   W     +   + +V  ++ ++I+ +  TQ NG+ + FDLE        +I   P + K I  +  D+FP++++GI L  EP +FH +  +++ F++EK + R     N  K  + +    DI+P EYGGK  ++ D
Sbjct:    5 RPGPLVGKQLNELPDHSPLLQPGLAELRRRVQEAGVPQTPQPLTDAFLLRFLRARDFDLDLAWRLMKNYYKWRAECPELS------ADLRPRSILGLLKAGYHGVLRSRDSTGSRVLIYRIAYWDPKVFTAYDVFRVSLITSELIVQEVETQRNGVKAIFDLEGWQVSHAFQI--TPSVAKKIAAVLTDSFPLKVRGIHLINEPVIFHAVFSMIKPFLTEKIKDRIHLHGNNYK-SSMLQHFPDILPREYGGKEFSMED 254
[Close]
BLAST of CRAL-TRIO domain-containing protein vs. Ensembl Mouse
Match: Clvs2 (clavesin 2 [Source:MGI Symbol;Acc:MGI:2443223])

HSP 1 Score: 84.7297 bits (208), Expect = 1.224e-17
Identity = 69/294 (23.47%), Postives = 130/294 (44.22%), Query Frame = 3 
Query:  324 YFYKNLSSRDQEILSKEIHENPLQVNAHIESFRRWVLSMPHLK-CPTDSRFLLKFLRIAKYDHSKAQKRLDNFCTIRASPQGAPLYFNFSGINSTLIEKVFRAHQNVPIGKTS----GNELVILYKTQDWSNDEMSVEVLLQVIYMSFDIILSKESTQINGIISFFDLERCNRKTLEIWSDPKLLKTITRIWQDAFPIRMKGIILYKEPFLFHVILKILEFFISEKHRKRFFQIDNTEKIFNCIPGL--EDIMPIEYGGKGGNLSDKVDLFYLENWIKEVKDFHSNRDSWWNFE 1184
            +    LS    E    E++ENP  ++  I+  R  V++ P +    TD  F+L+FLR  K+ H +A + L  +   R   Q   ++ +F   +  + + +       P G  +    G ++++L+   +W     ++  +L+ I +S + ++     Q+NG +   D      K     + P +L+      QD+FP R  GI    +P+  H +  ++  F+ EK RKR F   N     N +  L   +I+P E+GG        +  + +  W + + D   + DS +N +
Sbjct:    3 HLQAGLSPETLEKARLELNENPDTLHQDIQEVRDMVITRPDIGFLRTDDAFILRFLRARKFHHFEAFRLLAQYFEYRQ--QNLDMFKSFKATDPGIKQAL---KDGFPGGLANLDHYGRKILVLFAA-NWDQSRYTLVDILRAILLSLEAMIEDPELQVNGFVLIIDWSNFTFKQASKLT-PNMLRLAIEGLQDSFPARFGGIHFVNQPWYIHALYTVIRPFLKEKTRKRIFLHGNN---LNSLHQLIHPEILPSEFGG-------MLPPYDMGTWARTLLDHEYDDDSEYNVD 279
[Close]
BLAST of CRAL-TRIO domain-containing protein vs. Ensembl Mouse
Match: Clvs1 (clavesin 1 [Source:MGI Symbol;Acc:MGI:1921688])

HSP 1 Score: 77.411 bits (189), Expect = 4.178e-15
Identity = 60/254 (23.62%), Postives = 110/254 (43.31%), Query Frame = 3 
Query:  324 YFYKNLSSRDQEILSKEIHENPLQVNAHIESFRRWVLSMPHLK-CPTDSRFLLKFLRIAKYDHSKAQKRLDNFCTIRASPQGAPLYFNFSGINSTLIEKVFRAHQNVPIGKTSGNELVILYKTQDWSNDEMSVEVLLQVIYMSFDIILSKESTQINGIISFFDLERCNRKTLEIWSDPKLLKTITRIWQDAFPIRMKGIILYKEPFLFHVILKILEFFISEKHRKR-FFQIDNTEKIFNCIPGLEDIMPIEYGG 1079
            +    LS    E    E++ENP  ++  I+  R  +++ P +    TD  F+L+FLR  K+  + A + L  +   R       ++ NF   +  +   +      V   +      ++L    +W     S   +L+ I +S ++++     QING I   D    + K     + P +LK      QD+FP R  G+    +P+  H +  +++ F+ +K RKR F   +N   +   I    + +P E+GG
Sbjct:   25 HLQAGLSPDTIEKARLELNENPDILHQDIQQVRDMIITRPDIGFLRTDDAFILRFLRARKFHQADAFRLLAQYFQYRQ--LNLDMFKNFKADDPGIKRALIDGFPGVLENRDHYGRKILLLFAANWDQSRNSFTDILRAILLSLEVLIEDPELQINGFILIIDWSNFSFKQASKLT-PSILKLAIEGLQDSFPARFGGVHFVNQPWYIHALYTLIKPFLKDKTRKRIFLHGNNLNSLHQLI--HPEFLPSEFGG 273
[Close]
BLAST of CRAL-TRIO domain-containing protein vs. UniProt/SwissProt
Match: sp|Q9D3D0|TTPAL_MOUSE (Alpha-tocopherol transfer protein-like OS=Mus musculus OX=10090 GN=Ttpal PE=1 SV=3)

HSP 1 Score: 88.9669 bits (219), Expect = 4.253e-18
Identity = 72/266 (27.07%), Postives = 125/266 (46.99%), Query Frame = 3 
Query:  369 KEIHENPLQVNAHIESFRRWVL-SMPHLKCPTDSRFLLKFLRIAKYDHSKAQKRLDNFCTIRAS-PQGAPLYFNFSGINSTLIEKVFRAH--QNVPIGKTSGNELVILYKTQDWSNDEMSVEVLLQVIYMSFDIILSKESTQINGIISFFDLERCNRKTLEIWSDPKLLKTITRIWQDAFPIRMKGIILYKEPFLFHVILKILEFFISEKHRKRFF-QIDNTEKIFNCIPGLEDIMPIEYGGKGGNLS----DKVDLFYLENWIKE 1139
            +E+ E P      +++ R  V    P+L    D  FLL+FLR  K+D+ +A + L N+   R S P+       FS +  + ++ V  +     +P     G   V+  +   W      +   ++ +Y++ + ++  E TQ+NGI+   D +  +      +  P + K +  I QD FPIR+K + +  EP +F  I  I++ F+ EK   RFF    +   +   +P   +I+P EYGG  G L     + V L   E+++KE
Sbjct:   46 EELQEKPEWRLRDVQALRDMVRKEYPYLSTSLDDAFLLRFLRARKFDYDRALQLLVNYHGCRRSWPE------VFSNLRPSALKDVLNSGFLTVLPHTDPRGCH-VLCIRPDRWIPSNYPITENIRAVYLTLEKLIQSEETQVNGIVILADYKGVSLSKASHFG-PFIAKKVIGILQDGFPIRIKAVHIVNEPRIFKGIFAIIKPFLKEKIANRFFLHGSDLNSLHTNLP--RNILPKEYGGTAGELDTASWNAVLLASEEDFVKE 301
[Close]
BLAST of CRAL-TRIO domain-containing protein vs. UniProt/SwissProt
Match: sp|Q5RFR0|TTPAL_PONAB (Alpha-tocopherol transfer protein-like OS=Pongo abelii OX=9601 GN=TTPAL PE=2 SV=1)

HSP 1 Score: 87.0409 bits (214), Expect = 1.427e-17
Identity = 68/246 (27.64%), Postives = 116/246 (47.15%), Query Frame = 3 
Query:  369 KEIHENPLQVNAHIESFRRWVL-SMPHLKCPTDSRFLLKFLRIAKYDHSKAQKRLDNFCTIRASPQGAPLYFNFSGINSTLIEKVFRAH--QNVPIGKTSGNELVILYKTQDWSNDEMSVEVLLQVIYMSFDIILSKESTQINGIISFFDLERCNRKTLEIWSDPKLLKTITRIWQDAFPIRMKGIILYKEPFLFHVILKILEFFISEKHRKRFF-QIDNTEKIFNCIPGLEDIMPIEYGGKGGNL 1094
            +E+ E P      +++ R  V    P+L    D  FLL+FLR  K+D+ +A + L N+ + R S    P  FN   +  + ++ V  +     +P     G  +V + +   W      +   ++ IY++ + ++  E TQ+NGI+   D +  +      +  P + K +  I QD FPIR+K + +  EP +F  I  I++ F+ EK   RFF    +   +   +P    I+P EYGG  G L
Sbjct:   45 EELQEKPEWRLRDVQALRDMVRKEYPNLSTSLDDAFLLRFLRARKFDYDRALQLLVNYHSCRRS---WPEVFN--NLKPSALKDVLASGFLTVLPHTDPRGCHVVCI-RPDRWIPSNYPITENIRAIYLTLEKLIQSEETQVNGIVILADYKGVSLSKASHFG-PFIAKKVIGILQDGFPIRIKAVHVVNEPRIFKGIFAIIKPFLKEKIANRFFLHGSDLNSLHTNLP--RSILPKEYGGTAGEL 281
[Close]
BLAST of CRAL-TRIO domain-containing protein vs. UniProt/SwissProt
Match: sp|Q9BTX7|TTPAL_HUMAN (Alpha-tocopherol transfer protein-like OS=Homo sapiens OX=9606 GN=TTPAL PE=1 SV=2)

HSP 1 Score: 87.0409 bits (214), Expect = 1.468e-17
Identity = 68/246 (27.64%), Postives = 116/246 (47.15%), Query Frame = 3 
Query:  369 KEIHENPLQVNAHIESFRRWVL-SMPHLKCPTDSRFLLKFLRIAKYDHSKAQKRLDNFCTIRASPQGAPLYFNFSGINSTLIEKVFRAH--QNVPIGKTSGNELVILYKTQDWSNDEMSVEVLLQVIYMSFDIILSKESTQINGIISFFDLERCNRKTLEIWSDPKLLKTITRIWQDAFPIRMKGIILYKEPFLFHVILKILEFFISEKHRKRFF-QIDNTEKIFNCIPGLEDIMPIEYGGKGGNL 1094
            +E+ E P      +++ R  V    P+L    D  FLL+FLR  K+D+ +A + L N+ + R S    P  FN   +  + ++ V  +     +P     G  +V + +   W      +   ++ IY++ + ++  E TQ+NGI+   D +  +      +  P + K +  I QD FPIR+K + +  EP +F  I  I++ F+ EK   RFF    +   +   +P    I+P EYGG  G L
Sbjct:   45 EELQEKPEWRLRDVQALRDMVRKEYPNLSTSLDDAFLLRFLRARKFDYDRALQLLVNYHSCRRS---WPEVFN--NLKPSALKDVLASGFLTVLPHTDPRGCHVVCI-RPDRWIPSNYPITENIRAIYLTLEKLIQSEETQVNGIVILADYKGVSLSKASHFG-PFIAKKVIGILQDGFPIRIKAVHVVNEPRIFKGIFAIIKPFLKEKIANRFFLHGSDLNSLHTNLP--RSILPKEYGGTAGEL 281
[Close]
BLAST of CRAL-TRIO domain-containing protein vs. UniProt/SwissProt
Match: sp|P49638|TTPA_HUMAN (Alpha-tocopherol transfer protein OS=Homo sapiens OX=9606 GN=TTPA PE=1 SV=1)

HSP 1 Score: 84.7297 bits (208), Expect = 4.158e-17
Identity = 61/225 (27.11%), Postives = 110/225 (48.89%), Query Frame = 3 
Query:  435 SMPHLKCPTDSRFLLKFLRIAKYDHSKAQKRLDNFCTIRA-SPQ-GAPLYFNFSGINSTLIEKVFRAHQNVPIGKTSGNELVILYKTQDWSNDEMSVEVLLQVIYMSFDIILSKESTQINGIISFFDLERCN-RKTLEIWSDPKLLKTITRIWQDAFPIRMKGIILYKEPFLFHVILKILEFFISEKHRKRFFQIDNTEKIFNCIPGLEDIMPIEYGGKGGNLSD 1100
             +P    P    FLL+FLR   +D   A + L N+   RA  P+  A L+        ++I  +   +  V   +      V++Y+   W     +   + +V  ++ ++I+ +  TQ NGI + FDLE        +I   P + K I  +  D+FP++++GI L  EP +FH +  +++ F++EK ++R     N  K  + +    DI+P+EYGG+  ++ D
Sbjct:   39 GVPLAPLPLTDSFLLRFLRARDFDLDLAWRLLKNYYKWRAECPEISADLH------PRSIIGLLKAGYHGVLRSRDPTGSKVLIYRIAHWDPKVFTAYDVFRVSLITSELIVQEVETQRNGIKAIFDLEGWQFSHAFQI--TPSVAKKIAAVLTDSFPLKVRGIHLINEPVIFHAVFSMIKPFLTEKIKERIHMHGNNYKQ-SLLQHFPDILPLEYGGEEFSMED 254
[Close]
BLAST of CRAL-TRIO domain-containing protein vs. UniProt/SwissProt
Match: sp|P41034|TTPA_RAT (Alpha-tocopherol transfer protein OS=Rattus norvegicus OX=10116 GN=Ttpa PE=1 SV=1)

HSP 1 Score: 84.7297 bits (208), Expect = 4.531e-17
Identity = 69/260 (26.54%), Postives = 122/260 (46.92%), Query Frame = 3 
Query:  348 RDQEILSKEIHENPLQ---VNAHIESFRRWVL--SMPHLKCPTDSRFLLKFLRIAKYDHSKAQKRLDNFCTIRA-SPQ-GAPLY-FNFSGINSTLIEKVFRAHQNVPIGKTSGNELVILYKTQDWSNDEMSVEVLLQVIYMSFDIILSKESTQINGIISFFDLERCN-RKTLEIWSDPKLLKTITRIWQDAFPIRMKGIILYKEPFLFHVILKILEFFISEKHRKRFFQIDNTEKIFNCIPGLEDIMPIEYGGKGGNLSD 1100
            R   ++ K+++E P     V   +   RR      +P    P    FLL+FLR   +D   A + + N+   RA  P+  A L+  +  G+       V R+    P G       V++Y+   W     +   + +V  ++ ++I+ +  TQ NG+ + FDLE        +I   P + K I  +  D+FP++++GI L  EP +FH +  +++ F++EK + R     N  K  + +    DI+P+EYGG   ++ D
Sbjct:    5 RPGPVVGKQLNEQPDHSPLVQPGLAELRRRAQEEGVPETPQPLTDAFLLRFLRARDFDLDLAWRLMKNYYKWRAECPELSADLHPRSILGLLKAGYHGVLRSRD--PTGSR-----VLIYRISYWDPKVFTAYDVFRVSLITSELIVQEVETQRNGVKAIFDLEGWQISHAFQI--TPSVAKKIAAVVTDSFPLKVRGIHLINEPVIFHAVFSMIKPFLTEKIKGRIHLHGNNYK-SSLLQHFPDILPLEYGGNESSMED 254
[Close]
BLAST of CRAL-TRIO domain-containing protein vs. TrEMBL
Match: A0A267GCN2 (CRAL-TRIO domain-containing protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig023111g3 PE=4 SV=1)

HSP 1 Score: 229.95 bits (585), Expect = 3.951e-68
Identity = 119/323 (36.84%), Postives = 183/323 (56.66%), Query Frame = 3 
Query:  324 YFYKNLSSRDQEILSKEIHENPLQVNAHIESFRRWVLSMPHLKCPTDSRFLLKFLRIAKYDHSKAQKRLDNFCTIRASPQGAPLYFNFSGINSTLIEKVFRAHQNVPIGKTSGNELVILYKTQDWSNDEMSVEVLLQVIYMSFDIILSKESTQINGIISFFDLERCNRKTLEIWSDPKLLKTITRIWQDAFPIRMKGIILYKEPFLFHVILKILEFFISEKHRKRFFQIDNT-EKIFNCI-PGLEDIMPIEYGGKGGNLSDKVDLFYLENWIKEVKDFHSNRDSWWNFEVDEKKRQPDTKNFLKNYEDYVGETICGTPGSFIK 1286
            Y Y+ +  +D++   KE+HENP QV AHI S RRWV S PHL CPTD  FLL+FLR AK+D S+AQ+ +DNFCT+R SP+G+P +F    ++S +IE+  +   N+ +G     E +I     ++  D ++   L +  YM+ D ++  E  QING     +L+  N+K  + W +P+    + R WQDAFPIR K ++ + EP  F ++ +I+  F+ EK RKR  +      K+   I PG E ++P E GG+   + + +   Y    + +  +  + R       VDE KR P TK++LK Y+D    ++ G  G+F K
Sbjct:   10 YNYEGVDPKDKKKAQKELHENPDQVRAHIASLRRWVTSAPHLTCPTDDAFLLRFLRTAKFDQSRAQQLVDNFCTVRKSPRGSPEWFEPLPLDSPIIEETLKLPMNIFLGYNDDGEGIIYSSMDNYDPDRINFNDLARFAYMNADTMMKPEKIQINGCRFIMNLKNANKKQTQAWENPRTAFKMMRNWQDAFPIRTKALVYWHEPAFFELMFRIIMPFMKEKLRKRLHRCGTDFSKLKKAIGPGAERLLPPEMGGQNRPMEELLAERYK---MFKSAEAQAERAKLATITVDESKRLPTTKDYLKTYDDSADPSM-GIAGTFTK 328
[Close]
BLAST of CRAL-TRIO domain-containing protein vs. TrEMBL
Match: A0A267DVC9 (CRAL-TRIO domain-containing protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig023111g2 PE=4 SV=1)

HSP 1 Score: 229.95 bits (585), Expect = 4.124e-68
Identity = 119/323 (36.84%), Postives = 183/323 (56.66%), Query Frame = 3 
Query:  324 YFYKNLSSRDQEILSKEIHENPLQVNAHIESFRRWVLSMPHLKCPTDSRFLLKFLRIAKYDHSKAQKRLDNFCTIRASPQGAPLYFNFSGINSTLIEKVFRAHQNVPIGKTSGNELVILYKTQDWSNDEMSVEVLLQVIYMSFDIILSKESTQINGIISFFDLERCNRKTLEIWSDPKLLKTITRIWQDAFPIRMKGIILYKEPFLFHVILKILEFFISEKHRKRFFQIDNT-EKIFNCI-PGLEDIMPIEYGGKGGNLSDKVDLFYLENWIKEVKDFHSNRDSWWNFEVDEKKRQPDTKNFLKNYEDYVGETICGTPGSFIK 1286
            Y Y+ +  +D++   KE+HENP QV AHI S RRWV S PHL CPTD  FLL+FLR AK+D S+AQ+ +DNFCT+R SP+G+P +F    ++S +IE+  +   N+ +G     E +I     ++  D ++   L +  YM+ D ++  E  QING     +L+  N+K  + W +P+    + R WQDAFPIR K ++ + EP  F ++ +I+  F+ EK RKR  +      K+   I PG E ++P E GG+   + + +   Y    + +  +  + R       VDE KR P TK++LK Y+D    ++ G  G+F K
Sbjct:   10 YNYEGVDPKDKKKAQKELHENPDQVRAHIASLRRWVTSAPHLTCPTDDAFLLRFLRTAKFDQSRAQQLVDNFCTVRKSPRGSPEWFEPLPLDSPIIEEALKLPMNIFLGYNDDGEGIIYSSMDNYDPDRINFNDLARFAYMNADTMMKPEKIQINGCRFIMNLKNANKKQTQAWENPRTAFKMMRNWQDAFPIRTKALVYWHEPAFFELMFRIIMPFMKEKLRKRLHRCGTDFSKLKKAIGPGAERLLPPEMGGQNRPMEELLAERYK---MFKSAEAQAERAKLATITVDESKRLPTTKDYLKTYDDSADPSM-GIAGTFTK 328
[Close]
BLAST of CRAL-TRIO domain-containing protein vs. TrEMBL
Match: A0A267E9H4 (CRAL-TRIO domain-containing protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig023111g1 PE=4 SV=1)

HSP 1 Score: 229.18 bits (583), Expect = 8.451e-68
Identity = 118/323 (36.53%), Postives = 183/323 (56.66%), Query Frame = 3 
Query:  324 YFYKNLSSRDQEILSKEIHENPLQVNAHIESFRRWVLSMPHLKCPTDSRFLLKFLRIAKYDHSKAQKRLDNFCTIRASPQGAPLYFNFSGINSTLIEKVFRAHQNVPIGKTSGNELVILYKTQDWSNDEMSVEVLLQVIYMSFDIILSKESTQINGIISFFDLERCNRKTLEIWSDPKLLKTITRIWQDAFPIRMKGIILYKEPFLFHVILKILEFFISEKHRKRFFQIDNT-EKIFNCI-PGLEDIMPIEYGGKGGNLSDKVDLFYLENWIKEVKDFHSNRDSWWNFEVDEKKRQPDTKNFLKNYEDYVGETICGTPGSFIK 1286
            Y Y+ +  +D++   KE+HENP QV AHI S RRWV S PHL CPTD  FLL+FLR AK+D S+AQ+ +DNFCT+R SP+G+P +F    ++S +IE+  +   N+ +G     E +I     ++  D ++   L +  YM+ D ++  E  QING     +L+  N+K  + W +P+    + R WQDAFP+R K ++ + EP  F ++ +I+  F+ EK RKR  +      K+   I PG E ++P E GG+   + + +   Y    + +  +  + R       VDE KR P TK++LK Y+D    ++ G  G+F K
Sbjct:   10 YNYEGVDPKDKKKAQKELHENPDQVRAHIASLRRWVTSAPHLTCPTDDAFLLRFLRTAKFDQSRAQQLVDNFCTVRKSPRGSPEWFEPLPLDSPIIEEALKLPMNIFLGYNDDGEGIIYSSMDNYDPDRINFNDLARFAYMNADTMMKPEKIQINGCRFIMNLKNANKKQTQAWENPRTAFKMMRNWQDAFPMRTKALVYWHEPAFFELMFRIIMPFMKEKLRKRLHRCGTDFNKLKKAIGPGAERLLPPEMGGQNRPMEELLAERYK---MFKSAEAQAERAKLATITVDESKRLPTTKDYLKTYDDSADPSM-GIAGTFTK 328
[Close]
BLAST of CRAL-TRIO domain-containing protein vs. TrEMBL
Match: A0A1I8IZU0 (CRAL-TRIO domain-containing protein OS=Macrostomum lignano OX=282301 PE=4 SV=1)

HSP 1 Score: 229.565 bits (584), Expect = 1.543e-67
Identity = 119/323 (36.84%), Postives = 183/323 (56.66%), Query Frame = 3 
Query:  324 YFYKNLSSRDQEILSKEIHENPLQVNAHIESFRRWVLSMPHLKCPTDSRFLLKFLRIAKYDHSKAQKRLDNFCTIRASPQGAPLYFNFSGINSTLIEKVFRAHQNVPIGKTSGNELVILYKTQDWSNDEMSVEVLLQVIYMSFDIILSKESTQINGIISFFDLERCNRKTLEIWSDPKLLKTITRIWQDAFPIRMKGIILYKEPFLFHVILKILEFFISEKHRKRFFQIDNT-EKIFNCI-PGLEDIMPIEYGGKGGNLSDKVDLFYLENWIKEVKDFHSNRDSWWNFEVDEKKRQPDTKNFLKNYEDYVGETICGTPGSFIK 1286
            Y Y+ +  +D++   KE+HENP QV AHI S RRWV S PHL CPTD  FLL+FLR AK+D S+AQ+ +DNFCT+R SP+G+P +F    ++S +IE+  +   N+ +G     E +I     ++  D ++   L +  YM+ D ++  E  QING     +L+  N+K  + W +P+    + R WQDAFPIR K ++ + EP  F ++ +I+  F+ EK RKR  +      K+   I PG E ++P E GG+   + + +   Y    + +  +  + R       VDE KR P TK++LK Y+D    ++ G  G+F K
Sbjct:   10 YNYEGVDPKDKKKAQKELHENPDQVRAHIASLRRWVTSAPHLTCPTDDAFLLRFLRTAKFDQSRAQQLVDNFCTVRKSPRGSPEWFEPLPLDSPIIEEALKLPMNIFLGYNDDGEGIIYSSMDNYDPDRINFNDLARFAYMNADTMMKPEKIQINGCRFIMNLKNANKKQTQAWENPRTAFKMMRNWQDAFPIRTKALVYWHEPAFFELMFRIIMPFMKEKLRKRLHRCGTDFSKLKKAIGPGAERLLPPEMGGQNRPMEELLAERYK---MFKSAEAQAERAKLATITVDESKRLPTTKDYLKTYDDSADPSM-GIAGTFTK 328
[Close]
BLAST of CRAL-TRIO domain-containing protein vs. TrEMBL
Match: A0A1I8HCA4 (CRAL-TRIO domain-containing protein OS=Macrostomum lignano OX=282301 PE=4 SV=1)

HSP 1 Score: 229.565 bits (584), Expect = 2.141e-67
Identity = 119/323 (36.84%), Postives = 183/323 (56.66%), Query Frame = 3 
Query:  324 YFYKNLSSRDQEILSKEIHENPLQVNAHIESFRRWVLSMPHLKCPTDSRFLLKFLRIAKYDHSKAQKRLDNFCTIRASPQGAPLYFNFSGINSTLIEKVFRAHQNVPIGKTSGNELVILYKTQDWSNDEMSVEVLLQVIYMSFDIILSKESTQINGIISFFDLERCNRKTLEIWSDPKLLKTITRIWQDAFPIRMKGIILYKEPFLFHVILKILEFFISEKHRKRFFQIDNT-EKIFNCI-PGLEDIMPIEYGGKGGNLSDKVDLFYLENWIKEVKDFHSNRDSWWNFEVDEKKRQPDTKNFLKNYEDYVGETICGTPGSFIK 1286
            Y Y+ +  +D++   KE+HENP QV AHI S RRWV S PHL CPTD  FLL+FLR AK+D S+AQ+ +DNFCT+R SP+G+P +F    ++S +IE+  +   N+ +G     E +I     ++  D ++   L +  YM+ D ++  E  QING     +L+  N+K  + W +P+    + R WQDAFPIR K ++ + EP  F ++ +I+  F+ EK RKR  +      K+   I PG E ++P E GG+   + + +   Y    + +  +  + R       VDE KR P TK++LK Y+D    ++ G  G+F K
Sbjct:   10 YNYEGVDPKDKKKAQKELHENPDQVRAHIASLRRWVTSAPHLTCPTDDAFLLRFLRTAKFDQSRAQQLVDNFCTVRKSPRGSPEWFEPLPLDSPIIEEALKLPMNIFLGYNDDGEGIIYSSMDNYDPDRINFNDLARFAYMNADTMMKPEKIQINGCRFIMNLKNANKKQTQAWENPRTAFKMMRNWQDAFPIRTKALVYWHEPAFFELMFRIIMPFMKEKLRKRLHRCGTDFSKLKKAIGPGAERLLPPEMGGQNRPMEELLAERYK---MFKSAEAQAERAKLATITVDESKRLPTTKDYLKTYDDSADPSM-GIAGTFTK 328
[Close]
BLAST of CRAL-TRIO domain-containing protein vs. Ensembl Cavefish
Match: ttpal (alpha tocopherol transfer protein like [Source:NCBI gene;Acc:103043466])

HSP 1 Score: 86.6557 bits (213), Expect = 2.140e-18
Identity = 66/247 (26.72%), Postives = 115/247 (46.56%), Query Frame = 3 
Query:  369 KEIHENPLQVNAHIESFRRWVL-SMPHLKCPTDSRFLLKFLRIAKYDHSKAQKRLDNF-CTIRASPQGAPLYFNFSGINSTLIEKVFRAH--QNVPIGKTSGNELVILYKTQDWSNDEMSVEVLLQVIYMSFDIILSKESTQINGIISFFDLERCNRKTLEIWSDPKLLKTITRIWQDAFPIRMKGIILYKEPFLFHVILKILEFFISEKHRKRF-FQIDNTEKIFNCIPGLEDIMPIEYGGKGGNL 1094
            +E+ E P      +++ R  +L   P+L+   D  FLL+FLR  K+D+ +A + L N+  + RA P+       F  +  + ++ V        +P     G  ++ L +   W  ++      ++ IY++ + ++  E TQ+NGI+   D              P L K +  I QD FPIR+K + +  EP +F  I  I++ F+ EK  +R+     +   +   IP    ++P EYGG  G L
Sbjct:   48 EELQEKPEWRLRDVQALRDMILKEQPNLRTRLDDAFLLRFLRARKFDYDRAMQLLLNYHGSRRAWPE------VFQDLKPSTVKHVLDLGFLTVLPRPDPQGRYILCL-RPGKWKPNDYHFVDNIRAIYLTLEKLIQPEETQVNGIVILVDYTGVGLSQASN-PGPLLAKKVVSILQDGFPIRIKAVNIINEPRIFKGIFAIIKPFLKEKMAERYVLHGSDLSSLHRVIP--RSVLPEEYGGVAGRL 284
[Close]
BLAST of CRAL-TRIO domain-containing protein vs. Ensembl Cavefish
Match: ttpal (alpha tocopherol transfer protein like [Source:NCBI gene;Acc:103043466])

HSP 1 Score: 86.6557 bits (213), Expect = 2.303e-18
Identity = 68/249 (27.31%), Postives = 118/249 (47.39%), Query Frame = 3 
Query:  369 KEIHENPLQVNAHIESFRRWVL-SMPHLKCPTDSRFLLKFLRIAKYDHSKAQKRLDNF-CTIRASPQGAPLYFNFSGINSTLIEKVFRAH--QNVPIGKTSGNELVILYKTQDWSNDEMSVEVLLQVIYMSFDIILSKESTQINGIISFFDLERCNRKTLEIWSDPK--LLKTITRIWQDAFPIRMKGIILYKEPFLFHVILKILEFFISEKHRKRF-FQIDNTEKIFNCIPGLEDIMPIEYGGKGGNL 1094
            +E+ E P      +++ R  +L   P+L+   D  FLL+FLR  K+D+ +A + L N+  + RA P+       F  +  + ++ V        +P     G  ++ L +   W  ++      ++ IY++ + ++  E TQ+NGI+   D        L   S+P   L K +  I QD FPIR+K + +  EP +F  I  I++ F+ EK  +R+     +   +   IP    ++P EYGG  G L
Sbjct:   47 EELQEKPEWRLRDVQALRDMILKEQPNLRTRLDDAFLLRFLRARKFDYDRAMQLLLNYHGSRRAWPE------VFQDLKPSTVKHVLDLGFLTVLPRPDPQGRYILCL-RPGKWKPNDYHFVDNIRAIYLTLEKLIQPEETQVNGIVILVDYTGVG---LSQASNPGPLLAKKVVSILQDGFPIRIKAVNIINEPRIFKGIFAIIKPFLKEKMAERYVLHGSDLSSLHRVIP--RSVLPEEYGGVAGRL 283
[Close]
BLAST of CRAL-TRIO domain-containing protein vs. Ensembl Cavefish
Match: ttpa (tocopherol (alpha) transfer protein [Source:ZFIN;Acc:ZDB-GENE-030131-4631])

HSP 1 Score: 85.1149 bits (209), Expect = 1.653e-17
Identity = 62/217 (28.57%), Postives = 108/217 (49.77%), Query Frame = 3 
Query:  471 FLLKFLRIAKYDHSKAQKRLDNFCTIRASPQGAP-LYFNFSGINSTLIEKVFRAHQNVPIGKTSGNELVILYKTQDWSNDEMSVEVLLQVIYMSFDIILSKESTQINGIISFFDLER-CNRKTLEIWSDPKLLKTITRIWQDAFPIRMKGIILYKEPFLFHVILKILEFFISEKHRKR--FFQIDNTEKIFNCIPGLEDIMPIEYGGKGGNLSDKVD 1109
            FLLKFLR   +D   A K L N+   R   Q  P +  N     S++I  +   +  V   +      +++Y+   W+  E S   + +V  ++ ++I+ +  TQING+ + FDL+  C     +I  +P L K I+ +  D+FP++++GI L  EP  F  + K++  F+ +K ++R        T  ++   P  + I P EYGG G  L++  +
Sbjct:   48 FLLKFLRARDFDLDLALKLLINYHKWR---QECPEISANLQ--PSSVIGLLKNNYHGVLKSRDDAGSRILIYRISQWNPKEFSAYEVFRVSLITSELIVQERDTQINGLKAIFDLQGWCFAHAFQI--NPFLAKKISSVLTDSFPLKVRGIHLINEPIFFRPVFKMIRPFLPDKIKQRVHIHGSSYTASLYEHFP--KAIFPPEYGGTGPGLAEACE 255
[Close]
BLAST of CRAL-TRIO domain-containing protein vs. Ensembl Cavefish
Match: clvs2 (clavesin 2 [Source:NCBI gene;Acc:103047212])

HSP 1 Score: 82.0333 bits (201), Expect = 7.081e-17
Identity = 66/267 (24.72%), Postives = 116/267 (43.45%), Query Frame = 3 
Query:  324 YFYKNLSSRDQEILSKEIHENPLQVNAHIESFRRWVLSMPHLK-CPTDSRFLLKFLRIAKYDHSKA-----------QKRLDNFCTIRASPQG--APLYFNFSGINSTLIEKVFRAHQNVPIGKTSGNELVILYKTQDWSNDEMSVEVLLQVIYMSFDIILSKESTQINGIISFFDLERCNRKTLEIWSDPKLLKTITRIWQDAFPIRMKGIILYKEPFLFHVILKILEFFISEKHRKR-FFQIDNTEKIFNCIPGLEDIMPIEYGG 1079
            +    LS    E    E+ ENP  ++  I+  R  +++ P +    TD  F+L+FLR  K++H +A           Q+ LD F  ++A+  G    L   F G+ S L                 G ++++L+   +W     +   +L+ I +S + ++     Q+NG +   D      K     + P +L+      QD+FP R  GI    +P+  H +  ++  F+ +K RKR F   +N   +   I  + +I+P E GG
Sbjct:    3 HLQAGLSPETLEKAKVELKENPDTLHQDIQEVRDMIITRPDIGFLRTDDAFILRFLRARKFNHFEAFRLLAQYFEYRQQNLDMFKNLKATDPGIKQALKDGFPGVLSNL--------------DRHGRKILVLFAA-NWDQSRYTFVDILRAILLSLEAMIEDPELQVNGFVLIIDWSNFTFKQASKLT-PSMLRLAIEGLQDSFPARFGGIHFVNQPWYIHALYTVIRPFLKDKTRKRIFMHGNNLNSLHQLI--VPEILPSELGG 251
[Close]
BLAST of CRAL-TRIO domain-containing protein vs. Ensembl Cavefish
Match: clvs2 (clavesin 2 [Source:NCBI gene;Acc:103047212])

HSP 1 Score: 81.2629 bits (199), Expect = 1.887e-16
Identity = 66/267 (24.72%), Postives = 116/267 (43.45%), Query Frame = 3 
Query:  324 YFYKNLSSRDQEILSKEIHENPLQVNAHIESFRRWVLSMPHLK-CPTDSRFLLKFLRIAKYDHSKA-----------QKRLDNFCTIRASPQG--APLYFNFSGINSTLIEKVFRAHQNVPIGKTSGNELVILYKTQDWSNDEMSVEVLLQVIYMSFDIILSKESTQINGIISFFDLERCNRKTLEIWSDPKLLKTITRIWQDAFPIRMKGIILYKEPFLFHVILKILEFFISEKHRKR-FFQIDNTEKIFNCIPGLEDIMPIEYGG 1079
            +    LS    E    E+ ENP  ++  I+  R  +++ P +    TD  F+L+FLR  K++H +A           Q+ LD F  ++A+  G    L   F G+ S L                 G ++++L+   +W     +   +L+ I +S + ++     Q+NG +   D      K     + P +L+      QD+FP R  GI    +P+  H +  ++  F+ +K RKR F   +N   +   I  + +I+P E GG
Sbjct:   20 HLQAGLSPETLEKAKVELKENPDTLHQDIQEVRDMIITRPDIGFLRTDDAFILRFLRARKFNHFEAFRLLAQYFEYRQQNLDMFKNLKATDPGIKQALKDGFPGVLSNL--------------DRHGRKILVLFAA-NWDQSRYTFVDILRAILLSLEAMIEDPELQVNGFVLIIDWSNFTFKQASKLT-PSMLRLAIEGLQDSFPARFGGIHFVNQPWYIHALYTVIRPFLKDKTRKRIFMHGNNLNSLHQLI--VPEILPSELGG 268
[Close]
BLAST of CRAL-TRIO domain-containing protein vs. Ensembl Sea Lamprey
Match: ttpal (tocopherol (alpha) transfer protein-like [Source:ZFIN;Acc:ZDB-GENE-030131-296])

HSP 1 Score: 95.9005 bits (237), Expect = 7.606e-23
Identity = 69/240 (28.75%), Postives = 114/240 (47.50%), Query Frame = 3 
Query:  285 TSKRLFIERMADYYFYKNLSSRDQEILSKEIHENPLQVNAHIESFRRWVLSMPHLKCPTDSRFLLKFLRIAKYDHSKAQKRLDNFCTIRASPQGAPLYFNFSGINSTLIEKVFRAHQNVPIGKTSGNELVILYKTQDWSNDEMSVEVLLQVIYMSFDIILSKESTQINGIISFFDLERCNRKTLEIWSDPKLLKTITRIWQDAFPIRMKGIILYKEPFLFHVILKILEFFISEKHRKRFF 1004
            T  +L   +MA  Y   +LS    E    E+ ENP      ++  R  +   P +   TD  FLL+FLR  K+DH K  K ++++     +       F  S + + L     R    +P   + G   VI+     W+     +   ++ +YM+ ++++  E TQ+NGI    D +      +  ++ P L+K IT + QDAFPIR+KG     EP +F  +  +++ F+ EK RKR+F
Sbjct:   17 TDSQLSPLQMAGGYVC-SLSPELVERARVELGENPETRAQEVQKLREALARRPDIPARTDDAFLLRFLRARKFDHEKTFKLVESYYKCHETWPDIFQNFRPSAVKALLGSGFIRV---LPERDSKGRR-VIIQSPGKWNPSTTPMMDNIRAMYMTMELLIQSEETQVNGITILADHKGVRLAHVTNFT-PSLMKKITTVMQDAFPIRIKGHNTVNEPSIFKAMFALMKPFLKEKMRKRYF 250
[Close]
BLAST of CRAL-TRIO domain-containing protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000007468.1 (pep scaffold:Pmarinus_7.0:GL477833:5549:9144:1 gene:ENSPMAG00000006747.1 transcript:ENSPMAT00000007468.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 63.1586 bits (152), Expect = 2.562e-12
Identity = 35/116 (30.17%), Postives = 60/116 (51.72%), Query Frame = 3 
Query:  651 KTSGNELVILYKTQDWSNDEMSVEVLLQVIYMSFDIILSKESTQINGIISFFDLERCNRKTLEIWSDPKLLKTITRIWQDAFPIRMKGIILYKEPFLFHVILKILEFFISEKHRKR 998
            + S    VI+     W+     +    + +YM+ ++++  E TQ+NGI    D +      +  ++ P L+K IT + QDAFPIR+KG     EP +F  +  +++ F  EK +KR
Sbjct:   34 RDSKGRRVIIQSPGKWNPSTTPIIDNFKAMYMTLELLIQSEETQVNGITILVDHKGMGLAHVTNFT-PSLMKKITTVIQDAFPIRIKGHHTINEPSIFKAMFALIKPFFKEKMQKR 148
[Close]
BLAST of CRAL-TRIO domain-containing protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000003570.1 (pep scaffold:Pmarinus_7.0:GL486699:2092:8510:1 gene:ENSPMAG00000003262.1 transcript:ENSPMAT00000003570.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 65.0846 bits (157), Expect = 3.361e-12
Identity = 43/161 (26.71%), Postives = 76/161 (47.20%), Query Frame = 3 
Query:  327 FYKNLSSRDQEILSKEIHENPLQVNAHIESFRRWVLSMPHLKCPTDSRFLLKFLRIAKYDHSKAQKRLDNFCTIRASPQGAPLYFNFSGINSTLIEKVFRAHQNVPIGKTSGNELVILYKTQDWSNDEMSVEVLLQVIYMSFDIILSKESTQINGIISFFD 809
            +   LS    E+  +E+ E P      I++ R  +   P +  PTD  FLL+FLR  K+D+ KA   +DN+   R       + F  S +   L   V  A   +P     G  +++L +   W+        +L+V+YM+ ++++ +E TQ+ G++   D
Sbjct:   28 YVCRLSPHLVEVARQELQEKPEWRLRDIQALRDMLKEHPEIPAPTDDGFLLRFLRARKFDYDKALLLIDNYYKCRRVWPDVFVNFYPSSVRHVLEAGVVTA---LPQPDAQGRRIIVL-RPGLWNPAVAPATDMLRVLYMTLEMLVRQEETQVCGLVVLAD 184
[Close]
BLAST of CRAL-TRIO domain-containing protein vs. Ensembl Nematostella
Match: EDO33762 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SR95])

HSP 1 Score: 49.2914 bits (116), Expect = 1.064e-6
Identity = 32/148 (21.62%), Postives = 69/148 (46.62%), Query Frame = 3 
Query:  639 VPIGKTSGNELVILYKTQDWSNDEMSVEVLLQVIYMSFDIILSKESTQINGIISFFDLERCNRKTLEIWSDPKLLKTITRIWQDAFPIRMKGIILYKEPFLFHVILKILEFFISEKHRKR-FFQIDNTEKIFNCIPGLEDIMPIEYGG 1079
            +P     G+ +++L+    W  D  S + LLQ + ++   +    + Q  G++   D       T   + + K +K I  I+++ +P+  K + L  +P+    ++  L  F++ K + R F   +N   + + IP   + +P ++GG
Sbjct:   79 LPYMDPVGSTIMVLFPGM-WDTDTFSPDTLLQALMLTLMHLSESLTVQSRGVVLLVDFSEWT-STQAAYLNIKYIKKIVTIFENCYPVVFKSVHLINQPWYISALISFLRPFLTGKVKDRVFLHGNNLTTLHDHIP--PESLPSQFGG 222
[Close]
BLAST of CRAL-TRIO domain-containing protein vs. Ensembl Medaka
Match: ttpal (alpha tocopherol transfer protein like [Source:NCBI gene;Acc:101167039])

HSP 1 Score: 87.0409 bits (214), Expect = 1.656e-18
Identity = 67/247 (27.13%), Postives = 114/247 (46.15%), Query Frame = 3 
Query:  369 KEIHENPLQVNAHIESFRRWVL-SMPHLKCPTDSRFLLKFLRIAKYDHSKAQKRLDNF-CTIRASPQGAPLYFNFSGINSTLIEKVFRAH--QNVPIGKTSGNELVILYKTQDWSNDEMSVEVLLQVIYMSFDIILSKESTQINGIISFFDLERCNRKTLEIWSDPKLLKTITRIWQDAFPIRMKGIILYKEPFLFHVILKILEFFISEKHRKRF-FQIDNTEKIFNCIPGLEDIMPIEYGGKGGNL 1094
            +E+ E P      +++ R  +L   P+L    D  FLL+FLR  K+D+ +A + L N+    RA P+       F  +  + ++ V        +P    SG  ++ L +   W  ++      ++ IY++ + ++  E TQ+NGII   D              P L K +  I QD FPIR+K + +  EP +F  I  I++ F+ EK  +R+     +   +   +P    ++P EYGG  G L
Sbjct:   46 EELQEKPEWRLRDVQALRDMILKEQPNLHTRLDDAFLLRFLRARKFDYDRALQLLLNYHAGRRAWPE------VFQDLKPSTVKHVLDLGFLTVLPRPDPSGRYILCL-RPGKWKPNDYPFVDNVRAIYLTLEKLIQPEETQVNGIIILVDYTGVGMSQASN-PGPFLAKKVVSILQDGFPIRIKAVNIINEPLIFKGIFAIIKPFLKEKMAERYILHGSDLRSLHRNLPA--SVLPEEYGGTAGRL 282
[Close]
BLAST of CRAL-TRIO domain-containing protein vs. Ensembl Medaka
Match: CLVS1 (clavesin-1 [Source:NCBI gene;Acc:101158238])

HSP 1 Score: 85.8853 bits (211), Expect = 3.603e-18
Identity = 70/258 (27.13%), Postives = 122/258 (47.29%), Query Frame = 3 
Query:  324 YFYKNLSSRDQEILSKEIHENPLQVNAHIESFRRWVLSMPHLK-CPTDSRFLLKFLRIAKYDHSKAQKRLDNFCTIRASPQGAPLYFNFS----GINSTLIEKVFRAHQNVPIGKTSGNELVILYKTQDWSNDEMSVEVLLQVIYMSFDIILSKESTQINGIISFFDLERCNRKTLEIWSDPKLLKTITRIWQDAFPIRMKGIILYKEPFLFHVILKILEFFISEKHRKR-FFQIDNTEKIFNCIPGLEDIMPIEYGG 1079
            + + +LSS   E    E++ENP  ++  I+  R  +++ P +    TD  F+L+FLR  K+D  +  + L  +   R   Q   ++ +F     GI   L++  F      P     G +++IL+ + +W     S   +L+ I +S ++++     QING I   D    + K     + P +LK      QD+FP R  GI    +P+  H +  I++ F+ +K RKR F   +N   +   I  L + +P E+GG
Sbjct:    3 HLHSSLSSEMMEKARLELNENPDTLHQDIQQVRDMIVTRPDIGFLRTDDDFILRFLRARKFDQLETFRLLAQYFQFRQ--QNLDMFQSFKVDDLGIKRALMDG-FPGVLESP--DQHGRKILILFAS-NWDQSRNSFIDILRAILLSLEVLIENPELQINGFILIIDWSNFSFKQASKLT-PNILKLAIEGLQDSFPARFGGIHFVNQPWYIHAMYTIIKPFLKDKTRKRIFLHGNNLNSLHQLI--LPECLPSEFGG 251
[Close]
BLAST of CRAL-TRIO domain-containing protein vs. Ensembl Medaka
Match: clvs2 (clavesin 2 [Source:NCBI gene;Acc:101159632])

HSP 1 Score: 81.6481 bits (200), Expect = 1.066e-16
Identity = 67/266 (25.19%), Postives = 114/266 (42.86%), Query Frame = 3 
Query:  324 YFYKNLSSRDQEILSKEIHENPLQVNAHIESFRRWVLSMPHLK-CPTDSRFLLKFLRIAKYDHSKA-----------QKRLDNFCTIRASPQG--APLYFNFSGINSTLIEKVFRAHQNVPIGKTSGNELVILYKTQDWSNDEMSVEVLLQVIYMSFDIILSKESTQINGIISFFDLERCNRKTLEIWSDPKLLKTITRIWQDAFPIRMKGIILYKEPFLFHVILKILEFFISEKHRKRFFQIDNTEKIFNCIPGLEDIMPIEYGG 1079
            +    LS    E    E+ ENP  ++  I+  R  +++ P +    TD  F+L+FLR  K++H +A           Q+ LD F  ++A+  G    L   F G+ S L                 G ++++L+   +W     +   +L+ I +S + ++     Q+NG I   D      K     + P +L+      QD+FP R  GI    +P+  H +  ++  F+ +K RKR F   N     + +   E I+P E GG
Sbjct:    3 HLQAGLSPETLEKAKVELKENPDTLHQDIQEVRDMIITRPDIGFLRTDDAFILRFLRARKFNHFEAFRLLAQYFEYRQQNLDMFKNLKATDPGIKQALKDGFPGVLSNL--------------DKYGRKILVLFAA-NWDQSRYTFVDILRAILLSLESMIEDPELQVNGFILIIDWSNFTFKQASKLT-PSMLRLAIEGLQDSFPARFGGIHFVNQPWYIHALYTVIRPFLKDKTRKRIFMHGNNLNSLHQLINPE-ILPSELGG 251
[Close]
BLAST of CRAL-TRIO domain-containing protein vs. Ensembl Medaka
Match: TTPA (alpha tocopherol transfer protein [Source:NCBI gene;Acc:101155881])

HSP 1 Score: 67.3958 bits (163), Expect = 5.054e-12
Identity = 63/239 (26.36%), Postives = 111/239 (46.44%), Query Frame = 3 
Query:  456 PTDSRFLLKFLRIAKYDHSKAQKRLDNFCTIRASPQGAPLYFNFSGINSTLIEKVFRAHQNVPIGKTSGNELVILYKTQDWSNDEMSVEVLLQVIYMSFDIILSKESTQINGIISFFDLERCN-RKTLEIWSDPKLLKTITRIWQDAFPIRMKGIILYKEPFLFHVILKILEFFISEKHRKRF------FQIDNTEKIFNCIPGLEDIMPIEYGGKGGNLSDKVDLFYLENWIKEVKDF 1151
            P    FLLKFLR   +D   + K L N+   R   + +P   +    +S L       H  +P    +G+  V++Y+   W+  + S   + +V  M+ +II  +  TQ  G+ + FDL+  +    L+I  +P L K I+ +  D+FP++++GI L  EP  F  +  ++  F+ EK ++R       F  D     F+       ++P EYGG G  + +       ++W  ++  F
Sbjct:   50 PLSDGFLLKFLRARDFDVELSLKLLLNYLRWR---RDSPEISSCLSPSSVLGLLHMSYHAVLPQRDHAGSR-VLIYRIGQWNTKDWSPYQVFRVSLMTSEIISMETETQRRGLKAIFDLQGWSLGHALQI--NPSLAKKISCVLSDSFPLKVRGIHLVNEPRFFRPVFAMIRPFLPEKIKQRIHMHGADFHSD-LRHFFH-----PHVLPPEYGGHGPGIDEAC-----QDWTNQLLHF 271
[Close]
BLAST of CRAL-TRIO domain-containing protein vs. Ensembl Medaka
Match: TTPA (alpha tocopherol transfer protein [Source:NCBI gene;Acc:101155881])

HSP 1 Score: 67.0106 bits (162), Expect = 5.890e-12
Identity = 63/239 (26.36%), Postives = 111/239 (46.44%), Query Frame = 3 
Query:  456 PTDSRFLLKFLRIAKYDHSKAQKRLDNFCTIRASPQGAPLYFNFSGINSTLIEKVFRAHQNVPIGKTSGNELVILYKTQDWSNDEMSVEVLLQVIYMSFDIILSKESTQINGIISFFDLERCN-RKTLEIWSDPKLLKTITRIWQDAFPIRMKGIILYKEPFLFHVILKILEFFISEKHRKRF------FQIDNTEKIFNCIPGLEDIMPIEYGGKGGNLSDKVDLFYLENWIKEVKDF 1151
            P    FLLKFLR   +D   + K L N+   R   + +P   +    +S L       H  +P    +G+  V++Y+   W+  + S   + +V  M+ +II  +  TQ  G+ + FDL+  +    L+I  +P L K I+ +  D+FP++++GI L  EP  F  +  ++  F+ EK ++R       F  D     F+       ++P EYGG G  + +       ++W  ++  F
Sbjct:   47 PLSDGFLLKFLRARDFDVELSLKLLLNYLRWR---RDSPEISSCLSPSSVLGLLHMSYHAVLPQRDHAGSR-VLIYRIGQWNTKDWSPYQVFRVSLMTSEIISMETETQRRGLKAIFDLQGWSLGHALQI--NPSLAKKISCVLSDSFPLKVRGIHLVNEPRFFRPVFAMIRPFLPEKIKQRIHMHGADFHSD-LRHFFH-----PHVLPPEYGGHGPGIDEAC-----QDWTNQLLHF 268
[Close]
BLAST of CRAL-TRIO domain-containing protein vs. Planmine SMEST
Match: SMESG000009878.1 (SMESG000009878.1)

HSP 1 Score: 659.448 bits (1700), Expect = 0.000e+0
Identity = 323/330 (97.88%), Postives = 323/330 (97.88%), Query Frame = 3 
Query:  312 MADYYFYKNLSSRDQEILSKEIHENPLQVNAHIESFRRWVLSMPHLKCPTDSRFLLKFLRIAKYDHSKAQKRLDNFCTIRASPQGAPLYFNFSGINSTLIEKVFRAHQNVPIGKTSGNELVILYKTQDWSNDEMSVEVLLQVIYMSFDIILSKESTQINGIISFFDLERCNRKTLEIWSDPKLLKTITRIWQDAFPIRMKGIILYKEPFLFHVILKILEFFISEKHRKRFFQIDNTEKIFNCIPGLEDIMPIEYGGKGGNLSDKVDLFYLENWIKEVKDFHSNRDSWWNFEVDEKKRQPDTKNFLKNYEDYVGETICGTPGSFIKHKNVF 1301
            MAD Y YKNLSSRDQEILSKEIHENPLQVNAHIESFRRWVLSMPHLKCPTDSRFLLKFLRIAKYDHSKAQKRLDNFCTIRASPQGAPLYFNFSGINSTLIEKVFRAHQNVPIGKTSGNELVILYKTQDWSNDEMSVEVLLQVIYMSFDIILSKESTQINGIISFFDLERCNRKTLEIWSDPKLLKTITRIWQDAFPIRMKGIILYKEPFLFHVILKILEFFISEKHRKRFFQIDNTEKIFNCIPGLEDIMPIEYGGKGGNLSDKV     ENWIKEVKDFHSNRDSWWNFEVDEKKRQPDTKNFLKNYEDYVGETICGTPGSFIKHKNVF
Sbjct:    1 MADCYDYKNLSSRDQEILSKEIHENPLQVNAHIESFRRWVLSMPHLKCPTDSRFLLKFLRIAKYDHSKAQKRLDNFCTIRASPQGAPLYFNFSGINSTLIEKVFRAHQNVPIGKTSGNELVILYKTQDWSNDEMSVEVLLQVIYMSFDIILSKESTQINGIISFFDLERCNRKTLEIWSDPKLLKTITRIWQDAFPIRMKGIILYKEPFLFHVILKILEFFISEKHRKRFFQIDNTEKIFNCIPGLEDIMPIEYGGKGGNLSDKV-----ENWIKEVKDFHSNRDSWWNFEVDEKKRQPDTKNFLKNYEDYVGETICGTPGSFIKHKNVF 325
[Close]
BLAST of CRAL-TRIO domain-containing protein vs. Planmine SMEST
Match: SMESG000009877.1 (SMESG000009877.1)

HSP 1 Score: 445.662 bits (1145), Expect = 3.477e-156
Identity = 209/330 (63.33%), Postives = 262/330 (79.39%), Query Frame = 3 
Query:  312 MADYYFYKNLSSRDQEILSKEIHENPLQVNAHIESFRRWVLSMPHLKCPTDSRFLLKFLRIAKYDHSKAQKRLDNFCTIRASPQGAPLYFNFSGINSTLIEKVFRAHQNVPIGKTSGNELVILYKTQDWSNDEMSVEVLLQVIYMSFDIILSKESTQINGIISFFDLERCNRKTLEIWSDPKLLKTITRIWQDAFPIRMKGIILYKEPFLFHVILKILEFFISEKHRKRFFQIDNTEKIFNCIPGLEDIMPIEYGGKGGNLSDKVDLFYLENWIKEVKDFHSNRDSWWNFEVDEKKRQPDTKNFLKNYEDYVGETICGTPGSFIKHKNVF 1301
            MAD Y Y+ LS RD EIL  EI E+  QVNAHIESFRRWV+SMPHLKCPTDS+FLL FLR AK+DHS AQ+RLDNFCTIR+SP+G+P +F F  + +++IEKV R+HQN+P+GK S  E+V+L+KT DW  +E+SVE +LQV+YM+FD+IL++ESTQINGI+S FDLE C RKTLE WSDP L K I RIWQDAFPIRMKGIILYK P LFH+ILKI+EFF+ +KH+KR  QID+ +K+F+ + GL++IMP EYGG GG L DKV     E+WI EV+ F+   D W    VDE KR  DT +FL+NYE+Y GETI GTPGS+ K+++++
Sbjct:    1 MADVYKYETLSVRDSEILKNEIKEDKNQVNAHIESFRRWVVSMPHLKCPTDSKFLLMFLRTAKFDHSVAQRRLDNFCTIRSSPRGSPRFFKFPSLKNSIIEKVLRSHQNIPMGKDSAGEMVLLFKTGDWKPEEISVENILQVVYMTFDLILTRESTQINGIVSIFDLEGCCRKTLEAWSDPHLTKNIMRIWQDAFPIRMKGIILYKPPTLFHIILKIMEFFMIDKHKKRILQIDSQDKLFSKVSGLKEIMPTEYGGNGGKLKDKV-----ESWIGEVETFYDKGDPWSFISVDENKRPGDTVSFLRNYEEYKGETIGGTPGSYTKYEDLY 325
[Close]
BLAST of CRAL-TRIO domain-containing protein vs. Planmine SMEST
Match: SMESG000009988.1 (SMESG000009988.1)

HSP 1 Score: 339.732 bits (870), Expect = 1.264e-114
Identity = 158/326 (48.47%), Postives = 223/326 (68.40%), Query Frame = 3 
Query:  312 MADYYFYKNLSSRDQEILSKEIHENPLQVNAHIESFRRWVLSMPHLKCPTDSRFLLKFLRIAKYDHSKAQKRLDNFCTIRASPQGAPLYFNFSGINSTLIEKVFRAHQNVPIGKTSGNELVILYKTQDWSNDEMSVEVLLQVIYMSFDIILSKESTQINGIISFFDLERCNRKTLEIWSDPKLLKTITRIWQDAFPIRMKGIILYKEPFLFHVILKILEFFISEKHRKRFFQI-DNTEKIFNCIPGLEDIMPIEYGGKGGNLSDKVDLFYLENWIKEVKDFHSNRDSWWNFEVDEKKRQPDTKNFLKNYEDYVGETICGTPGSFIK 1286
            MAD Y Y  L+ RD+++   E++E+P QVNAHIESFRRWV SMPHL CPTDSRFLL FLR+AK+DH+KAQKRLDNFCT+R+S +G P YF F  IN  + EK F+  Q +P+G+T   E +    +  W+  E+ ++ L+QV++MS ++ L  +  QI G+ +F D+  C +  +E  SDPK++K +TR+WQD +PIR KG ++Y+EP  + V   I+EFF++EKHRKR F+I ++ +K F  IPGLE ++P EYGGKG  + + +D      W KEV+DF++    W N  VDE KR  +T  + + Y DY GE++ GT G+F K
Sbjct:    1 MADTYTYDGLTDRDKQVALTELNEDPKQVNAHIESFRRWVKSMPHLNCPTDSRFLLMFLRVAKFDHAKAQKRLDNFCTVRSSARGHPEYFQFPDINDAVFEKFFQTKQMIPLGRTVDGETLFFGVSNLWNPKEIPIKKLMQVMFMSLEVQLQNQYLQIYGMKAFMDMHGCGKSFMEAVSDPKVMKAMTRVWQDCYPIRFKGQVIYREPGWYSVFYNIMEFFLNEKHRKRVFRIKEDIQKGFEKIPGLEALLPEEYGGKGPKMDEAID-----KWAKEVRDFYTKGSPWANISVDESKRPVETLKYFEQYADYTGESL-GTKGTFTK 320
[Close]
BLAST of CRAL-TRIO domain-containing protein vs. Planmine SMEST
Match: SMESG000009876.1 (SMESG000009876.1)

HSP 1 Score: 302.753 bits (774), Expect = 4.747e-100
Identity = 139/331 (41.99%), Postives = 218/331 (65.86%), Query Frame = 3 
Query:  312 MADYYFYKNLSSRDQEILSKEIHENPLQVNAHIESFRRWVLSMPHLKCPTDSRFLLKFLRIAKYDHSKAQKRLDNFCTIRASPQGAPLYFNFSGINSTLIEKVFRAHQNVPIGKTSGNELVILYKTQDWSNDEMSVEVLLQVIYMSFDIILSKESTQINGIISFFDLERCNRKTLEIWSDPKLLKTITRIWQDAFPIRMKGIILYKEPFLFHVILKILEFFISEKHRKRFFQIDN-TEKIFNCIPGLEDIMPIEYGGKGGNLSDKVDLFYLENWIKEVKDFHSNRDSWWNFEVDEKKRQPDTKNFLKNYEDYVGETICGTPGSFIKHKNVF 1301
            M + Y Y  +S + ++    +I ENP QVNAHIESFRRW+ SMPHL+CPTD++FL+KFLR++K+DH +A+KR+DN+CT+RASP+G+P +FN   IN  +I        ++P+G+T   E + L +T+ W  +++    L+ +++M+ DII + E TQI+G+    DL+  +RK +E W DPK +K I R+ Q+++P+R+KG I Y EP +F ++ ++L FF++EK + R  +I N   K     PGL+ I+P+EYGG+GG +++       E W    K+F+ N +    F VDE KR  ++ ++L  Y DY G+T+ GT G++ K +NVF
Sbjct:    1 MTERYEYSGISEKTKQFAIDDIGENPSQVNAHIESFRRWLKSMPHLQCPTDAKFLMKFLRVSKFDHKRAEKRIDNYCTVRASPRGSPSFFNTFSINDPIINTYLETGMHLPLGRTENGETIFLVRTKVWDPEQIPFPKLIILMFMAMDIICNDEETQIHGMKMIIDLKDASRKAMESWGDPKYMKQINRVMQESYPLRIKGTIFYNEPVIFDIVFQVLSFFMNEKMKSRTIRIKNDINKAIEKNPGLDKILPMEYGGQGGTITE-----CSEKWKIRFKEFYKNGNPVSGFSVDESKRPQESASYLAEYPDYEGQTL-GTQGTYTKFENVF 325
[Close]
BLAST of CRAL-TRIO domain-containing protein vs. Planmine SMEST
Match: SMESG000009874.1 (SMESG000009874.1)

HSP 1 Score: 292.738 bits (748), Expect = 4.366e-96
Identity = 140/331 (42.30%), Postives = 211/331 (63.75%), Query Frame = 3 
Query:  312 MADYYFYKNLSSRDQEILSKEIHENPLQVNAHIESFRRWVLSMPHLKCPTDSRFLLKFLRIAKYDHSKAQKRLDNFCTIRASPQGAPLYFNFSGINSTLIEKVFRAHQNVPIGKTSGNELVILYKTQDWSNDEMSVEVLLQVIYMSFDIILSKESTQINGIISFFDLERCNRKTLEIWSDPKLLKTITRIWQDAFPIRMKGIILYKEPFLFHVILKILEFFISEKHRKRFFQIDN-TEKIFNCIPGLEDIMPIEYGGKGGNLSDKVDLFYLENWIKEVKDFHSNRDSWWNFEVDEKKRQPDTKNFLKNYEDYVGETICGTPGSFIKHKNVF 1301
            M D Y Y  +S R ++    ++ ENP QVNAHIESFRRWV SMPHL CPTDS FLLKFLR++K+DH K QKRLDNFCT+R+SP+G+P +F++  ++  +++    +   +P+G+    E+++L K + W ++++ V   L + +M  DI+LS+E TQI+G+    DL+  +RK++E  ++PK+LK      QD++PIRMK  I   EP +F V+ +I  FF+++K R R  +I N   K F  +PG++ ++P EY G+GG L      +  E W    K ++ N D      V+E KR  +T ++L  Y+DYVG T+ GT G+F K +NV 
Sbjct:    1 MQDRYEYNRISERSKQFAIDDLGENPSQVNAHIESFRRWVKSMPHLICPTDSEFLLKFLRVSKFDHKKTQKRLDNFCTVRSSPRGSPDFFHYFNVDDPIVDMYLDSKVQLPLGRNDAGEMILLMKPEGWDSEKIPVNQFLSLFFMGLDILLSEEETQIHGLTLLIDLKDVSRKSIEAMAEPKILKQYNMAVQDSYPIRMKKQIFCNEPVIFDVVFQIYSFFMNDKMRGRTHRIKNDINKAFEKVPGIKTVLPTEYNGEGGTLE-----YCAEKWKHRFKTYYKNGDPLKGISVEEAKRPKETASYLVAYKDYVGPTL-GTHGTFTKFENVL 325
The following BLAST results are available for this feature:
BLAST of CRAL-TRIO domain-containing protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
TTPAL3.057e-1827.64alpha tocopherol transfer protein like [Source:HGN... [more]
TTPAL3.057e-1827.64alpha tocopherol transfer protein like [Source:HGN... [more]
TTPA8.659e-1827.11alpha tocopherol transfer protein [Source:HGNC Sym... [more]
CLVS21.817e-1723.47clavesin 2 [Source:HGNC Symbol;Acc:HGNC:23046][more]
CLVS12.541e-1523.62clavesin 1 [Source:HGNC Symbol;Acc:HGNC:23139][more]
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BLAST of CRAL-TRIO domain-containing protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of CRAL-TRIO domain-containing protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
CG339661.848e-2123.68gene:FBgn0053966 transcript:FBtr0100007[more]
CG316362.483e-2125.26gene:FBgn0051636 transcript:FBtr0079324[more]
CG316362.483e-2125.26gene:FBgn0051636 transcript:FBtr0343865[more]
CG129261.006e-1925.41gene:FBgn0033437 transcript:FBtr0088502[more]
CG26632.219e-1825.94gene:FBgn0037323 transcript:FBtr0078795[more]
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BLAST of CRAL-TRIO domain-containing protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ttpal3.441e-1826.91tocopherol (alpha) transfer protein-like [Source:Z... [more]
ttpal9.807e-1827.03tocopherol (alpha) transfer protein-like [Source:Z... [more]
clvs25.489e-1725.09clavesin 2 [Source:NCBI gene;Acc:566769][more]
ttpa6.492e-1425.35tocopherol (alpha) transfer protein [Source:ZFIN;A... [more]
rlbp1b2.867e-1023.87retinaldehyde binding protein 1b [Source:ZFIN;Acc:... [more]
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BLAST of CRAL-TRIO domain-containing protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ttpal3.395e-2228.33tocopherol (alpha) transfer protein-like [Source:N... [more]
thg1l9.465e-1824.42tRNA-histidine guanylyltransferase 1-like [Source:... [more]
clvs12.104e-1625.18clavesin 1 [Source:NCBI gene;Acc:100037913][more]
clvs16.749e-1625.47clavesin 1 [Source:NCBI gene;Acc:100037913][more]
ggh1.593e-1527.65gamma-glutamyl hydrolase (conjugase, folylpolygamm... [more]
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BLAST of CRAL-TRIO domain-containing protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Ttpal6.081e-1927.07tocopherol (alpha) transfer protein-like [Source:M... [more]
Ttpal6.081e-1927.07tocopherol (alpha) transfer protein-like [Source:M... [more]
Ttpa1.004e-1725.87tocopherol (alpha) transfer protein [Source:MGI Sy... [more]
Clvs21.224e-1723.47clavesin 2 [Source:MGI Symbol;Acc:MGI:2443223][more]
Clvs14.178e-1523.62clavesin 1 [Source:MGI Symbol;Acc:MGI:1921688][more]
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BLAST of CRAL-TRIO domain-containing protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q9D3D0|TTPAL_MOUSE4.253e-1827.07Alpha-tocopherol transfer protein-like OS=Mus musc... [more]
sp|Q5RFR0|TTPAL_PONAB1.427e-1727.64Alpha-tocopherol transfer protein-like OS=Pongo ab... [more]
sp|Q9BTX7|TTPAL_HUMAN1.468e-1727.64Alpha-tocopherol transfer protein-like OS=Homo sap... [more]
sp|P49638|TTPA_HUMAN4.158e-1727.11Alpha-tocopherol transfer protein OS=Homo sapiens ... [more]
sp|P41034|TTPA_RAT4.531e-1726.54Alpha-tocopherol transfer protein OS=Rattus norveg... [more]
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BLAST of CRAL-TRIO domain-containing protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A267GCN23.951e-6836.84CRAL-TRIO domain-containing protein OS=Macrostomum... [more]
A0A267DVC94.124e-6836.84CRAL-TRIO domain-containing protein OS=Macrostomum... [more]
A0A267E9H48.451e-6836.53CRAL-TRIO domain-containing protein OS=Macrostomum... [more]
A0A1I8IZU01.543e-6736.84CRAL-TRIO domain-containing protein OS=Macrostomum... [more]
A0A1I8HCA42.141e-6736.84CRAL-TRIO domain-containing protein OS=Macrostomum... [more]
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BLAST of CRAL-TRIO domain-containing protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ttpal2.140e-1826.72alpha tocopherol transfer protein like [Source:NCB... [more]
ttpal2.303e-1827.31alpha tocopherol transfer protein like [Source:NCB... [more]
ttpa1.653e-1728.57tocopherol (alpha) transfer protein [Source:ZFIN;A... [more]
clvs27.081e-1724.72clavesin 2 [Source:NCBI gene;Acc:103047212][more]
clvs21.887e-1624.72clavesin 2 [Source:NCBI gene;Acc:103047212][more]
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BLAST of CRAL-TRIO domain-containing protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 3
Match NameE-valueIdentityDescription
ttpal7.606e-2328.75tocopherol (alpha) transfer protein-like [Source:Z... [more]
ENSPMAT00000007468.12.562e-1230.17pep scaffold:Pmarinus_7.0:GL477833:5549:9144:1 gen... [more]
ENSPMAT00000003570.13.361e-1226.71pep scaffold:Pmarinus_7.0:GL486699:2092:8510:1 gen... [more]
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BLAST of CRAL-TRIO domain-containing protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of CRAL-TRIO domain-containing protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 1
Match NameE-valueIdentityDescription
EDO337621.064e-621.62Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of CRAL-TRIO domain-containing protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ttpal1.656e-1827.13alpha tocopherol transfer protein like [Source:NCB... [more]
CLVS13.603e-1827.13clavesin-1 [Source:NCBI gene;Acc:101158238][more]
clvs21.066e-1625.19clavesin 2 [Source:NCBI gene;Acc:101159632][more]
TTPA5.054e-1226.36alpha tocopherol transfer protein [Source:NCBI gen... [more]
TTPA5.890e-1226.36alpha tocopherol transfer protein [Source:NCBI gen... [more]
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BLAST of CRAL-TRIO domain-containing protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000009878.10.000e+097.88SMESG000009878.1[more]
SMESG000009877.13.477e-15663.33SMESG000009877.1[more]
SMESG000009988.11.264e-11448.47SMESG000009988.1[more]
SMESG000009876.14.747e-10041.99SMESG000009876.1[more]
SMESG000009874.14.366e-9642.30SMESG000009874.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30028995 ID=SMED30028995|Name=CRAL-TRIO domain-containing protein|organism=Schmidtea mediterranea sexual|type=transcript|length=1363bp
TTGTTATTATTATTTATAAAATCAAAATTTGAAATACAAATAACAGAAAT
ATATATTATTTGAATTTGAAGTGTATATTGGCTTGAGCTTACACCGTAGC
AAGTATAGGGCTCTCTTAAACAATAAAAAATGACCTTGTCACCATTCTCA
TTTACATTTATTTACTTACACTCAAGTTTGTGTGATGTATGTAAGCTTTC
AAGGATCCAATGACAGAATCTGTCACTAAGAAATTTAATGAAGGGATGAC
CTTTGATCACGGTTGATTATAAAAACCCAGATTCACCAGTAAAAGGTTGT
TCATTGAAAGAATGGCTGATTACTATTTCTATAAAAACCTATCATCAAGA
GACCAAGAAATCTTATCGAAAGAAATTCATGAAAACCCTTTACAAGTGAA
TGCTCATATTGAAAGCTTCAGACGATGGGTCTTGTCTATGCCTCATTTGA
AATGTCCTACAGATTCAAGGTTTTTGTTGAAGTTTCTTCGGATAGCAAAA
TATGACCATTCAAAAGCTCAAAAACGTTTAGACAATTTCTGTACGATTCG
AGCATCCCCTCAAGGAGCTCCTTTATATTTCAATTTTTCGGGTATAAATA
GTACGTTGATTGAGAAAGTATTTAGAGCTCATCAAAATGTGCCGATAGGA
AAAACCTCAGGCAACGAGCTTGTAATTCTATATAAAACACAAGATTGGAG
CAATGATGAAATGTCTGTCGAAGTCCTGTTGCAAGTCATCTACATGTCAT
TTGACATAATTCTGTCAAAAGAAAGCACTCAAATCAATGGAATAATAAGC
TTCTTTGATCTGGAAAGATGCAATAGAAAGACCCTTGAAATATGGTCAGA
TCCTAAATTACTGAAAACAATTACCCGCATATGGCAGGATGCCTTTCCAA
TTAGAATGAAAGGAATAATCTTATACAAGGAGCCATTTTTGTTTCATGTT
ATTCTGAAAATTTTGGAGTTTTTTATCTCCGAGAAGCACCGGAAAAGATT
TTTCCAAATCGATAATACTGAAAAGATTTTCAATTGTATCCCGGGACTTG
AAGACATTATGCCTATTGAGTACGGAGGAAAAGGTGGAAATCTTTCAGAT
AAAGTTGACCTTTTTTATTTAGAAAACTGGATCAAAGAAGTGAAAGATTT
TCACTCTAACAGAGATTCTTGGTGGAACTTTGAAGTTGATGAGAAAAAAC
GACAACCAGATACGAAAAACTTTTTAAAGAATTATGAAGATTATGTTGGA
GAAACTATCTGTGGAACTCCAGGATCATTTATTAAACACAAAAACGTTTT
TTAACCAATTTAATAATAAAACATATAAAAAATTTCTATAATTTTCGGAT
CGACACGATTTCA
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protein sequence of SMED30028995-orf-1

>SMED30028995-orf-1 ID=SMED30028995-orf-1|Name=SMED30028995-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=331bp
MADYYFYKNLSSRDQEILSKEIHENPLQVNAHIESFRRWVLSMPHLKCPT
DSRFLLKFLRIAKYDHSKAQKRLDNFCTIRASPQGAPLYFNFSGINSTLI
EKVFRAHQNVPIGKTSGNELVILYKTQDWSNDEMSVEVLLQVIYMSFDII
LSKESTQINGIISFFDLERCNRKTLEIWSDPKLLKTITRIWQDAFPIRMK
GIILYKEPFLFHVILKILEFFISEKHRKRFFQIDNTEKIFNCIPGLEDIM
PIEYGGKGGNLSDKVDLFYLENWIKEVKDFHSNRDSWWNFEVDEKKRQPD
TKNFLKNYEDYVGETICGTPGSFIKHKNVF*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000420parapharyngeal region
Vocabulary: INTERPRO
TermDefinition
IPR036865CRAL-TRIO_dom_sf
IPR036273CRAL/TRIO_N_dom_sf
IPR001071CRAL-bd_toc_tran
IPR001251CRAL-TRIO_dom
IPR011074CRAL/TRIO_N_dom
Vocabulary: molecular function
TermDefinition
GO:0005215transporter activity
GO:0008289lipid binding
GO:0008431vitamin E binding
GO:0019842vitamin binding
GO:0043325phosphatidylinositol-3,4-bisphosphate binding
GO:0005515protein binding
GO:0005546phosphatidylinositol-4,5-bisphosphate binding
Vocabulary: biological process
TermDefinition
GO:0006810transport
GO:0006629lipid metabolic process
GO:0007584response to nutrient
GO:0009268response to pH
GO:0009636response to toxic substance
GO:0032502developmental process
GO:0042360vitamin E metabolic process
GO:0046909intermembrane transport
GO:0051180vitamin transport
GO:0051452intracellular pH reduction
GO:0060548negative regulation of cell death
GO:0090212negative regulation of establishment of blood-brain barrier
GO:0001890placenta development
GO:0001892embryonic placenta development
Vocabulary: cellular component
TermDefinition
GO:0005622intracellular
GO:0005737cytoplasm
GO:0005770late endosome
GO:0005829cytosol
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
NoneNo IPR availablePRINTSPR00180CRETINALDHBPcoord: 54..76
score: 35.87
coord: 182..203
score: 34.09
coord: 248..257
score: 57.5
NoneNo IPR availableGENE3DG3DSA:1.10.8.20coord: 4..82
e-value: 2.5E-8
score: 35.9
NoneNo IPR availablePANTHERPTHR10174RETINALDEHYDE BINDING PROTEIN-RELATEDcoord: 9..300
IPR001251CRAL-TRIO lipid binding domainSMARTSM00516sec14_4coord: 99..259
e-value: 4.1E-5
score: 33.0
IPR001251CRAL-TRIO lipid binding domainPFAMPF00650CRAL_TRIOcoord: 118..257
e-value: 1.4E-15
score: 57.4
IPR001251CRAL-TRIO lipid binding domainPROSITEPS50191CRAL_TRIOcoord: 117..262
score: 12.115
IPR001251CRAL-TRIO lipid binding domainCDDcd00170SEC14coord: 117..257
e-value: 1.6826E-18
score: 78.9662
IPR036865CRAL-TRIO lipid binding domain superfamilyGENE3DG3DSA:3.40.525.10coord: 92..265
e-value: 1.1E-32
score: 114.7
IPR036865CRAL-TRIO lipid binding domain superfamilySUPERFAMILYSSF52087CRAL/TRIO domaincoord: 103..269
IPR036273CRAL/TRIO, N-terminal domain superfamilySUPERFAMILYSSF46938CRAL/TRIO N-terminal domaincoord: 16..82