Glutamate receptor ionotropic, NMDA 2B

Overview
NameGlutamate receptor ionotropic, NMDA 2B
Smed IDSMED30028945
Length (bp)3582
Neoblast Clusters

Zeng et. al., 2018




▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 



 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)




Explore this single cell expression dataset with our NB Cluster Shiny App




 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Glutamate receptor ionotropic, NMDA 2B (SMED30028945) t-SNE clustered cells

Violin plots show distribution of expression levels for Glutamate receptor ionotropic, NMDA 2B (SMED30028945) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Glutamate receptor ionotropic, NMDA 2B (SMED30028945) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Glutamate receptor ionotropic, NMDA 2B (SMED30028945) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017




Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020




SMED30028945

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 5

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
head regionSMED30028945h1SMcG0017750 SmedASXL_014724SmedAsxl_ww_GCZZ01PMID:27034770
Currie et al., 2016
whole organism asexual adult RNA-sequencing evidence
muscle cellSMED30028945h1SMcG0017750 dd_Smed_v4_14850_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
prepharyngeal regionSMED30028945h1SMcG0017750 dd_Smed_v6_14850_0_1dd_Smed_v6PMID:28171748
Stückemann et al., 2017
whole organism asexual adult RNA-sequencing evidence
head regionSMED30028945h1SMcG0017750 OX_Smed_1.0.06344ox_Smed_v2PMID:24238224
Kao et al., 2013
whole organism asexual adult RNA-sequencing evidence
enteric muscle cellSMED30028945h1SMcG0017750 dd_Smed_v4_14850_0_1dd_Smed_v4PMID:30471994
Scimone et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
BLAST of Glutamate receptor ionotropic, NMDA 2B vs. Ensembl Human
Match: GRIN2A (glutamate ionotropic receptor NMDA type subunit 2A [Source:HGNC Symbol;Acc:HGNC:4585])

HSP 1 Score: 326.25 bits (835), Expect = 3.558e-93
Identity = 186/503 (36.98%), Postives = 280/503 (55.67%), Query Frame = 2
Query: 1430 WTKVGTWIMSSTLEEKRTKLQIDGVTWPGEVNKPPLGRPSKFKLRVSTLKEEPFVIFSVKQ--DKTCGNNALACSVLHDSLSISVDDFEKSKNRTKYLYMGNENY-TDACCTGMAIDILRELMKDLNFEVDLYEVPDRKWGAWSAEKGWNGLLESLINRKVDMAVSAFKITPNRSEQVDFTVPFQETGIAILVALHEGSISPTAFLKPYDWASWMVILIFSVHCCSTAMFIYEWLSPKGLDRG---NVPPREHKFSLFRALWLIWAMLFGASVNVDSPRGMASRFLGCIWALFGLVFLASYTANLAAFMIAKEDHYDLKGLNDWRFQRPWNFKPEFRFATVPFSASEENIALNYPDIALYMRRYNKSSVEEGIRALKQKEIDAFIYDSNVLEFRAAKDEGCKLRTVGN--LYAVTGYGIAFPKGSKWYSKVNDLIMQYQKYDLLHRWKTFWLTGACKKTDKLANTNRTLGVRNFISAFXXXXXXXXXXXXXXXCEHLFFRYLR 2914
            W KVG W       E  T L +    WP          P    L + TL+E PFVI        +TC  N + C             F K  N T      NE      CC G  IDIL++L + + F  DLY V + K G       WNG++  ++ ++  MAV +  I   RSE VDF+VPF ETGI+++V+   G++SP+AFL+P+  + W+++ +  +   + A+F++E+ SP G +R       P    F++ +A+WL+W ++F  SV V +P+G  S+ +  +WA F ++FLASYTANLAAFMI +E    + GL+D +FQRP ++ P FRF TVP  ++E NI  NYP +  YM ++N+  VE+ + +LK  ++DAFIYD+ VL ++A +DEGCKL T+G+  ++A TGYGIA  KGS W  +++  ++Q+     +   +T WLTG C   +K    +  L + N    F +L   + +S +  I EHLF+  LR
Sbjct:  235 WEKVGKW-------ENHT-LSLRHAVWP-RYKSFSDCEPDDNHLSIVTLEEAPFVIVEDIDPLTETCVRNTVPCR-----------KFVKINNST------NEGMNVKKCCKGFCIDILKKLSRTVKFTYDLYLVTNGKHGK-KVNNVWNGMIGEVVYQRAVMAVGSLTINEERSEVVDFSVPFVETGISVMVSRSNGTVSPSAFLEPFSASVWVMMFVMLLIVSAIAVFVFEYFSPVGYNRNLAKGKAPHGPSFTIGKAIWLLWGLVFNNSVPVQNPKGTTSKIMVSVWAFFAVIFLASYTANLAAFMIQEEFVDQVTGLSDKKFQRPHDYSPPFRFGTVPNGSTERNIRNNYPYMHQYMTKFNQKGVEDALVSLKTGKLDAFIYDAAVLNYKAGRDEGCKLVTIGSGYIFATTGYGIALQKGSPWKRQIDLALLQFVGDGEMEELETLWLTGIC-HNEKNEVMSSQLDIDNMAGVFYMLAAAMALSLITFIWEHLFYWKLR 709          
BLAST of Glutamate receptor ionotropic, NMDA 2B vs. Ensembl Human
Match: GRIN2A (glutamate ionotropic receptor NMDA type subunit 2A [Source:HGNC Symbol;Acc:HGNC:4585])

HSP 1 Score: 325.865 bits (834), Expect = 2.181e-92
Identity = 186/503 (36.98%), Postives = 280/503 (55.67%), Query Frame = 2
Query: 1430 WTKVGTWIMSSTLEEKRTKLQIDGVTWPGEVNKPPLGRPSKFKLRVSTLKEEPFVIFSVKQ--DKTCGNNALACSVLHDSLSISVDDFEKSKNRTKYLYMGNENY-TDACCTGMAIDILRELMKDLNFEVDLYEVPDRKWGAWSAEKGWNGLLESLINRKVDMAVSAFKITPNRSEQVDFTVPFQETGIAILVALHEGSISPTAFLKPYDWASWMVILIFSVHCCSTAMFIYEWLSPKGLDRG---NVPPREHKFSLFRALWLIWAMLFGASVNVDSPRGMASRFLGCIWALFGLVFLASYTANLAAFMIAKEDHYDLKGLNDWRFQRPWNFKPEFRFATVPFSASEENIALNYPDIALYMRRYNKSSVEEGIRALKQKEIDAFIYDSNVLEFRAAKDEGCKLRTVGN--LYAVTGYGIAFPKGSKWYSKVNDLIMQYQKYDLLHRWKTFWLTGACKKTDKLANTNRTLGVRNFISAFXXXXXXXXXXXXXXXCEHLFFRYLR 2914
            W KVG W       E  T L +    WP          P    L + TL+E PFVI        +TC  N + C             F K  N T      NE      CC G  IDIL++L + + F  DLY V + K G       WNG++  ++ ++  MAV +  I   RSE VDF+VPF ETGI+++V+   G++SP+AFL+P+  + W+++ +  +   + A+F++E+ SP G +R       P    F++ +A+WL+W ++F  SV V +P+G  S+ +  +WA F ++FLASYTANLAAFMI +E    + GL+D +FQRP ++ P FRF TVP  ++E NI  NYP +  YM ++N+  VE+ + +LK  ++DAFIYD+ VL ++A +DEGCKL T+G+  ++A TGYGIA  KGS W  +++  ++Q+     +   +T WLTG C   +K    +  L + N    F +L   + +S +  I EHLF+  LR
Sbjct:  372 WEKVGKW-------ENHT-LSLRHAVWP-RYKSFSDCEPDDNHLSIVTLEEAPFVIVEDIDPLTETCVRNTVPCR-----------KFVKINNST------NEGMNVKKCCKGFCIDILKKLSRTVKFTYDLYLVTNGKHGK-KVNNVWNGMIGEVVYQRAVMAVGSLTINEERSEVVDFSVPFVETGISVMVSRSNGTVSPSAFLEPFSASVWVMMFVMLLIVSAIAVFVFEYFSPVGYNRNLAKGKAPHGPSFTIGKAIWLLWGLVFNNSVPVQNPKGTTSKIMVSVWAFFAVIFLASYTANLAAFMIQEEFVDQVTGLSDKKFQRPHDYSPPFRFGTVPNGSTERNIRNNYPYMHQYMTKFNQKGVEDALVSLKTGKLDAFIYDAAVLNYKAGRDEGCKLVTIGSGYIFATTGYGIALQKGSPWKRQIDLALLQFVGDGEMEELETLWLTGICHN-EKNEVMSSQLDIDNMAGVFYMLAAAMALSLITFIWEHLFYWKLR 846          
BLAST of Glutamate receptor ionotropic, NMDA 2B vs. Ensembl Human
Match: GRIN2A (glutamate ionotropic receptor NMDA type subunit 2A [Source:HGNC Symbol;Acc:HGNC:4585])

HSP 1 Score: 325.865 bits (834), Expect = 7.985e-92
Identity = 186/503 (36.98%), Postives = 280/503 (55.67%), Query Frame = 2
Query: 1430 WTKVGTWIMSSTLEEKRTKLQIDGVTWPGEVNKPPLGRPSKFKLRVSTLKEEPFVIFSVKQ--DKTCGNNALACSVLHDSLSISVDDFEKSKNRTKYLYMGNENY-TDACCTGMAIDILRELMKDLNFEVDLYEVPDRKWGAWSAEKGWNGLLESLINRKVDMAVSAFKITPNRSEQVDFTVPFQETGIAILVALHEGSISPTAFLKPYDWASWMVILIFSVHCCSTAMFIYEWLSPKGLDRG---NVPPREHKFSLFRALWLIWAMLFGASVNVDSPRGMASRFLGCIWALFGLVFLASYTANLAAFMIAKEDHYDLKGLNDWRFQRPWNFKPEFRFATVPFSASEENIALNYPDIALYMRRYNKSSVEEGIRALKQKEIDAFIYDSNVLEFRAAKDEGCKLRTVGN--LYAVTGYGIAFPKGSKWYSKVNDLIMQYQKYDLLHRWKTFWLTGACKKTDKLANTNRTLGVRNFISAFXXXXXXXXXXXXXXXCEHLFFRYLR 2914
            W KVG W       E  T L +    WP          P    L + TL+E PFVI        +TC  N + C             F K  N T      NE      CC G  IDIL++L + + F  DLY V + K G       WNG++  ++ ++  MAV +  I   RSE VDF+VPF ETGI+++V+   G++SP+AFL+P+  + W+++ +  +   + A+F++E+ SP G +R       P    F++ +A+WL+W ++F  SV V +P+G  S+ +  +WA F ++FLASYTANLAAFMI +E    + GL+D +FQRP ++ P FRF TVP  ++E NI  NYP +  YM ++N+  VE+ + +LK  ++DAFIYD+ VL ++A +DEGCKL T+G+  ++A TGYGIA  KGS W  +++  ++Q+     +   +T WLTG C   +K    +  L + N    F +L   + +S +  I EHLF+  LR
Sbjct:  372 WEKVGKW-------ENHT-LSLRHAVWP-RYKSFSDCEPDDNHLSIVTLEEAPFVIVEDIDPLTETCVRNTVPCR-----------KFVKINNST------NEGMNVKKCCKGFCIDILKKLSRTVKFTYDLYLVTNGKHGK-KVNNVWNGMIGEVVYQRAVMAVGSLTINEERSEVVDFSVPFVETGISVMVSRSNGTVSPSAFLEPFSASVWVMMFVMLLIVSAIAVFVFEYFSPVGYNRNLAKGKAPHGPSFTIGKAIWLLWGLVFNNSVPVQNPKGTTSKIMVSVWAFFAVIFLASYTANLAAFMIQEEFVDQVTGLSDKKFQRPHDYSPPFRFGTVPNGSTERNIRNNYPYMHQYMTKFNQKGVEDALVSLKTGKLDAFIYDAAVLNYKAGRDEGCKLVTIGSGYIFATTGYGIALQKGSPWKRQIDLALLQFVGDGEMEELETLWLTGIC-HNEKNEVMSSQLDIDNMAGVFYMLAAAMALSLITFIWEHLFYWKLR 846          
BLAST of Glutamate receptor ionotropic, NMDA 2B vs. Ensembl Human
Match: GRIN2A (glutamate ionotropic receptor NMDA type subunit 2A [Source:HGNC Symbol;Acc:HGNC:4585])

HSP 1 Score: 325.865 bits (834), Expect = 7.985e-92
Identity = 186/503 (36.98%), Postives = 280/503 (55.67%), Query Frame = 2
Query: 1430 WTKVGTWIMSSTLEEKRTKLQIDGVTWPGEVNKPPLGRPSKFKLRVSTLKEEPFVIFSVKQ--DKTCGNNALACSVLHDSLSISVDDFEKSKNRTKYLYMGNENY-TDACCTGMAIDILRELMKDLNFEVDLYEVPDRKWGAWSAEKGWNGLLESLINRKVDMAVSAFKITPNRSEQVDFTVPFQETGIAILVALHEGSISPTAFLKPYDWASWMVILIFSVHCCSTAMFIYEWLSPKGLDRG---NVPPREHKFSLFRALWLIWAMLFGASVNVDSPRGMASRFLGCIWALFGLVFLASYTANLAAFMIAKEDHYDLKGLNDWRFQRPWNFKPEFRFATVPFSASEENIALNYPDIALYMRRYNKSSVEEGIRALKQKEIDAFIYDSNVLEFRAAKDEGCKLRTVGN--LYAVTGYGIAFPKGSKWYSKVNDLIMQYQKYDLLHRWKTFWLTGACKKTDKLANTNRTLGVRNFISAFXXXXXXXXXXXXXXXCEHLFFRYLR 2914
            W KVG W       E  T L +    WP          P    L + TL+E PFVI        +TC  N + C             F K  N T      NE      CC G  IDIL++L + + F  DLY V + K G       WNG++  ++ ++  MAV +  I   RSE VDF+VPF ETGI+++V+   G++SP+AFL+P+  + W+++ +  +   + A+F++E+ SP G +R       P    F++ +A+WL+W ++F  SV V +P+G  S+ +  +WA F ++FLASYTANLAAFMI +E    + GL+D +FQRP ++ P FRF TVP  ++E NI  NYP +  YM ++N+  VE+ + +LK  ++DAFIYD+ VL ++A +DEGCKL T+G+  ++A TGYGIA  KGS W  +++  ++Q+     +   +T WLTG C   +K    +  L + N    F +L   + +S +  I EHLF+  LR
Sbjct:  372 WEKVGKW-------ENHT-LSLRHAVWP-RYKSFSDCEPDDNHLSIVTLEEAPFVIVEDIDPLTETCVRNTVPCR-----------KFVKINNST------NEGMNVKKCCKGFCIDILKKLSRTVKFTYDLYLVTNGKHGK-KVNNVWNGMIGEVVYQRAVMAVGSLTINEERSEVVDFSVPFVETGISVMVSRSNGTVSPSAFLEPFSASVWVMMFVMLLIVSAIAVFVFEYFSPVGYNRNLAKGKAPHGPSFTIGKAIWLLWGLVFNNSVPVQNPKGTTSKIMVSVWAFFAVIFLASYTANLAAFMIQEEFVDQVTGLSDKKFQRPHDYSPPFRFGTVPNGSTERNIRNNYPYMHQYMTKFNQKGVEDALVSLKTGKLDAFIYDAAVLNYKAGRDEGCKLVTIGSGYIFATTGYGIALQKGSPWKRQIDLALLQFVGDGEMEELETLWLTGIC-HNEKNEVMSSQLDIDNMAGVFYMLAAAMALSLITFIWEHLFYWKLR 846          
BLAST of Glutamate receptor ionotropic, NMDA 2B vs. Ensembl Human
Match: GRIN2D (glutamate ionotropic receptor NMDA type subunit 2D [Source:HGNC Symbol;Acc:HGNC:4588])

HSP 1 Score: 323.553 bits (828), Expect = 2.091e-91
Identity = 188/505 (37.23%), Postives = 285/505 (56.44%), Query Frame = 2
Query: 1421 VTSWTKVGTWIMSSTLEEKRTKLQIDGVTWPGEVNKPPLGRPSKFKLRVSTLKEEPFVIFSVKQ--DKTCGNNALACSVLHDSLSISVDDFEKSKNRTKYLYMGNENYTDACCTGMAIDILRELMKDLNFEVDLYEVPDRKWGAWSAEKGWNGLLESLINRKVDMAVSAFKITPNRSEQVDFTVPFQETGIAILVALHEGSISPTAFLKPYDWASWMVILIFSVHCCSTAMFIYEWLSPKGLDRG---NVPPREHKFSLFRALWLIWAMLFGASVNVDSPRGMASRFLGCIWALFGLVFLASYTANLAAFMIAKEDHYDLKGLNDWRFQRPWNFKPEFRFATVPFSASEENIALNYPDIALYMRRYNKSSVEEGIRALKQKEIDAFIYDSNVLEFRAAKDEGCKLRTVGN--LYAVTGYGIAFPKGSKWYSKVNDLIMQYQKYDLLHRWKTFWLTGACKKTDKLANTNRTLGVRNFISAFXXXXXXXXXXXXXXXCEHLFFRYLR 2914
            V S T+  TW +  + E++  +L+    +  G   +P         L V+TL+E PFVI         TC  +++ C    +       D  + + R              CC G  IDIL+ L   + F  DLY V + K G    +  WNG++  +  ++ DMA+ +  I   RSE VDF+VPF ETGI+++VA   G++SP+AFL+PY  A W+++ +  +   +  +FI+E+LSP G +R       P    F++ +++WL+WA++F  SV V++PRG  S+ +  +WA F ++FLASYTANLAAFMI +E    + GL+D +FQRP    P  +F TVP  ++E+NI  NYPD+  YM RYN+  VEE +  LK  ++DAFIYD+ VL + A KDEGCKL T+G+  ++A TGYGIA  KGS+W   ++  ++Q+   D +   +  WL+G C   DK+   +  L + N    F +LL  + +S L+   EHL +  LR
Sbjct:  389 VISLTRDRTWEVVGSWEQQTLRLKYPLWSRYGRFLQP---VDDTQHLTVATLEERPFVIVEPADPISGTCIRDSVPCRSQLNRTHSPPPDAPRPEKR--------------CCKGFCIDILKRLAHTIGFSYDLYLVTNGKHGK-KIDGVWNGMIGEVFYQRADMAIGSLTINEERSEIVDFSVPFVETGISVMVARSNGTVSPSAFLEPYSPAVWVMMFVMCLTVVAVTVFIFEYLSPVGYNRSLATGKRPGGSTFTIGKSIWLLWALVFNNSVPVENPRGTTSKIMVLVWAFFAVIFLASYTANLAAFMIQEEYVDTVSGLSDRKFQRPQEQYPPLKFGTVPNGSTEKNIRSNYPDMHSYMVRYNQPRVEEALTQLKAGKLDAFIYDAAVLNYMARKDEGCKLVTIGSGKVFATTGYGIALHKGSRWKRPIDLALLQFLGDDEIEMLERLWLSGICHN-DKIEVMSSKLDIDNMAGVFYMLLVAMGLSLLVFAWEHLVYWRLR 874          
BLAST of Glutamate receptor ionotropic, NMDA 2B vs. Ensembl Celegans
Match: nmr-2 (NMDA class glutamate Receptor [Source:UniProtKB/TrEMBL;Acc:E0AHC1])

HSP 1 Score: 424.476 bits (1090), Expect = 1.735e-130
Identity = 239/616 (38.80%), Postives = 352/616 (57.14%), Query Frame = 2
Query: 1208 LNCQSKVDRNDAWTFGKYIYKFMSTLSV---------DYNSNFYQFSVHNYLNSTSFLVMNTRSILDKSPLYEMEKEKHFVTSWTKVGTWIMSSTLEEKRTKLQIDGVTWPGEVNKPPLGRPSKFKLRVSTLKEEPFVIFS-VKQD--KTCGNNALACSVLHDSLSIS-VDDFEKSKNRTKYLYMGNENYTDACCTGMAIDILRELMKDLNFEVDLYEVPDRKWGAWSAEKGWNGLLESLINRKVDMAVSAFKITPNRSEQVDFTVPFQETGIAILVALHEGSISPTAFLKPYDWASWMVILIFSVHCCSTAMFIYEWLSPKGLDRGNVPPREHKFSLFRALWLIWAMLFGASVNVDSPRGMASRFLGCIWALFGLVFLASYTANLAAFMIAKEDHYDLKGLNDWRFQRPWNFKPEFRFATVPFSASEENIALNYPDIALYMR--RYNKSSVEEGIRALKQKEIDAFIYDSNVLEFRAAKDEGCKLRTVGNLYAVTGYGIAFPKGSKWYSKVNDLIMQYQKYDLLHRWKTFWLTGACKKTDKLANTNRTLGVRNFISAFXXXXXXXXXXXXXXXCEHLFFRYLRPRMSNLDQYGCCGLISLSMGQLLSFEQTVNQT 3010
            ++C+S+ D +  W  GKYIY+ M    V          ++S FY F     L ++   + N R+          + EK    +W KVG +           +L++  V WPGE   PP G   KF ++V TL E PF+  S V  D  K  GN    C    D   +   D     KNRT             CC+G  +D+L +L  D+ F   LY+V D KWG    E GWNGL+  L++ K DM V++ K+   R+  +DF++PF +TGI+I+V +  G +SPTAFL+P+++++W++IL   +H  + ++F++EW+SP   +    PP EHKFSLFR+ WL+WA LF ASV+ D P+   SR +  +WA FGL FLA YTANLAAFMI +  +YDL G++D     P + KP FRF TV    + E +  N+  +  Y++  +Y + ++  GI A+K +E+DAFIYD+ VL++ A KD  C L TVG   ++TGYGI FPK S   S VN  ++QYQ+   L R + FWLTGAC         +  LG+ NF+SAF+LL  G+I+S ++L  EH++  +LR  +  +D  G CG+IS++MG+ L+F + V++ 
Sbjct:  358 VSCKSE-DGDPYWDNGKYIYEHMKAAFVKGNPFHVDDGHDSFFYTFEKTGRLRNSILQISNLRT--------NSKGEK----TWEKVGIFT--------NNELKMADVQWPGEKANPPQGAADKFHVKVVTLHEPPFIAVSDVDPDTQKCPGNQGSIC----DWGDVEYTDGAGVKKNRTLL----------KCCSGYCVDLLNKLANDIGFTYTLYKVRDEKWGL-KTENGWNGLIADLMHNKADMCVTSLKLNSERARDIDFSLPFLDTGISIIVKIRSGVLSPTAFLEPFEYSTWVIILFVCIHVAAISIFLFEWVSPYSFNMQKYPPPEHKFSLFRSYWLVWATLFSASVSTDVPKSTVSRLMALVWAAFGLTFLAVYTANLAAFMITRVQYYDLSGIHDPMLNFPHDQKPPFRFGTVDGGNTHETMKRNWHKMHEYVKHNKYFRMNISAGIEAVKNEELDAFIYDAVVLDYWAGKDANCALMTVGKWASMTGYGIGFPKNSPHTSLVNHYMLQYQQKGDLERLQNFWLTGACTPDSHSQTQSAPLGIENFLSAFVLLAGGIIVSVIVLGFEHIYCMHLRKPLQKIDPNGWCGIISMAMGKSLTFTEAVDRV 937          
BLAST of Glutamate receptor ionotropic, NMDA 2B vs. Ensembl Celegans
Match: nmr-2 (NMDA class glutamate Receptor [Source:UniProtKB/TrEMBL;Acc:E0AHC1])

HSP 1 Score: 335.88 bits (860), Expect = 4.023e-104
Identity = 163/376 (43.35%), Postives = 247/376 (65.69%), Query Frame = 2
Query: 1889 INRKVDMAVSAFKITPNRSEQVDFTVPFQETGIAILVALHEGSISPTAFLKPYDWASWMVILIFSVHCCSTAMFIYEWLSPKGLDRGNVPPREHKFSLFRALWLIWAMLFGASVNVDSPRGMASRFLGCIWALFGLVFLASYTANLAAFMIAKEDHYDLKGLNDWRFQRPWNFKPEFRFATVPFSASEENIALNYPDIALYMR--RYNKSSVEEGIRALKQKEIDAFIYDSNVLEFRAAKDEGCKLRTVGNLYAVTGYGIAFPKGSKWYSKVNDLIMQYQKYDLLHRWKTFWLTGACKKTDKLANTNRTLGVRNFISAFXXXXXXXXXXXXXXXCEHLFFRYLRPRMSNLDQYGCCGLISLSMGQLLSFEQTVNQT 3010
            ++ K DM V++ K+   R+  +DF++PF +TGI+I+V +  G +SPTAFL+P+++++W++IL   +H  + ++F++EW+SP   +    PP EHKFSLFR+ WL+WA LF ASV+ D P+   SR +  +WA FGL FLA YTANLAAFMI +  +YDL G++D     P + KP FRF TV    + E +  N+  +  Y++  +Y + ++  GI A+K +E+DAFIYD+ VL++ A KD  C L TVG   ++TGYGI FPK S   S VN  ++QYQ+   L R + FWLTGAC         +  LG+ NF+SAF+LL  G+I+S ++L  EH++  +LR  +  +D  G CG+IS++MG+ L+F + V++ 
Sbjct:    1 MHNKADMCVTSLKLNSERARDIDFSLPFLDTGISIIVKIRSGVLSPTAFLEPFEYSTWVIILFVCIHVAAISIFLFEWVSPYSFNMQKYPPPEHKFSLFRSYWLVWATLFSASVSTDVPKSTVSRLMALVWAAFGLTFLAVYTANLAAFMITRVQYYDLSGIHDPMLNFPHDQKPPFRFGTVDGGNTHETMKRNWHKMHEYVKHNKYFRMNISAGIEAVKNEELDAFIYDAVVLDYWAGKDANCALMTVGKWASMTGYGIGFPKNSPHTSLVNHYMLQYQQKGDLERLQNFWLTGACTPDSHSQTQSAPLGIENFLSAFVLLAGGIIVSVIVLGFEHIYCMHLRKPLQKIDPNGWCGIISMAMGKSLTFTEAVDRV 376          
BLAST of Glutamate receptor ionotropic, NMDA 2B vs. Ensembl Celegans
Match: nmr-1 (NMDA class glutamate Receptor; NMDA-type ionotropic glutamate receptor NMR-1 [Source:UniProtKB/TrEMBL;Acc:G5EGQ9])

HSP 1 Score: 155.221 bits (391), Expect = 6.019e-38
Identity = 127/462 (27.49%), Postives = 203/462 (43.94%), Query Frame = 2
Query: 1484 KLQIDGVTWPGEVNKPPLGRPSKFKLRVSTLKEEPFV----IFSVKQDKTCGNNALACSVLHDSLSISVDDFE---KSKNRTKYLYMGNENYTDACCTGMAIDILRELMK-------DLNFEVDLYEVPDRKWGAWSAEKG----WNGLLESLINRKVDMAVSAFKITPNRSEQVDFTVPFQETGIAILVALHEGSISPTAFLKPYDWASWMVILIFSVHCCSTAMFIYEWLSP----KGLDRGNVPPREHKFSLF------------RALWLIWAMLFGASVNVDSPRGMASRFLGCIWALFGLVFLASYTANLAAFMIAKEDHYDLKGLNDWRFQRPWNFKPEFRFATVPFSASEENIALNYPDIALY--MRRYNKSSVEEGIRALKQKEIDAFIYDSNVLEFRAAKDEGCKLRTVGNLYAVTGYGIAFPKGSKWYSKVNDLIMQYQKYDLLHRWKTFWL 2761
            +L  D + W G      +  P    LRV T+ + PFV    I S  Q    GN  +  S+  D + +S   +      +N T+Y           CC G+AID+L  L         D +F   L+   +  +G   A +      +G++  L     DMA+    I P R   VDFT P+   GI IL           +FL+P   + W  + I SV     A++  ++ SP       D+      + +F L+             A+W +W +L  + V+  +PR  ++R LG +W  F ++ +ASYTANLAAF++  +    L G+ D R + P      F F TV  S   +    +    +++  M  +N     E + +L    +DAFI+DS  LEF AA+   C+LRT G+L+  + YGI   K S W   +   I++  +  ++ +    W+
Sbjct:  374 RLDEDSIEWAGGTKPLEISLPKH--LRVVTVADPPFVYTTPIGSPSQCAELGNTVVEWSIF-DKIVVSGPWYSCPLTLENSTEYF----------CCAGLAIDLLSNLSLPEANNSIDTSFTFSLHL--NESYGVVQASETTGITISGVIGELDGDTADMAIGGITINPERERIVDFTEPWLYHGIRILEKNIPRDSPMQSFLQPLQSSLWTALFI-SVILVGLAIYCLDFKSPFERFYQADKEMEQDLKKEFELWIGKDADENVNFGEAMWFVWGVLLNSGVSEKTPRSCSARVLGIVWCGFCMIMVASYTANLAAFLVLDQPEKGLTGVTDPRLRNP---SANFSFGTVLNSNVYQYFKRHVELSSMFRKMEPHNVRRASEAVHSLLNGSLDAFIWDSTRLEFEAARH--CELRTRGSLFGRSAYGIGLQKNSPWTPHITSAILRMSESGVMEKLDQKWI 814          
BLAST of Glutamate receptor ionotropic, NMDA 2B vs. Ensembl Celegans
Match: nmr-1 (NMDA class glutamate Receptor; NMDA-type ionotropic glutamate receptor NMR-1 [Source:UniProtKB/TrEMBL;Acc:G5EGQ9])

HSP 1 Score: 155.221 bits (391), Expect = 6.019e-38
Identity = 127/462 (27.49%), Postives = 203/462 (43.94%), Query Frame = 2
Query: 1484 KLQIDGVTWPGEVNKPPLGRPSKFKLRVSTLKEEPFV----IFSVKQDKTCGNNALACSVLHDSLSISVDDFE---KSKNRTKYLYMGNENYTDACCTGMAIDILRELMK-------DLNFEVDLYEVPDRKWGAWSAEKG----WNGLLESLINRKVDMAVSAFKITPNRSEQVDFTVPFQETGIAILVALHEGSISPTAFLKPYDWASWMVILIFSVHCCSTAMFIYEWLSP----KGLDRGNVPPREHKFSLF------------RALWLIWAMLFGASVNVDSPRGMASRFLGCIWALFGLVFLASYTANLAAFMIAKEDHYDLKGLNDWRFQRPWNFKPEFRFATVPFSASEENIALNYPDIALY--MRRYNKSSVEEGIRALKQKEIDAFIYDSNVLEFRAAKDEGCKLRTVGNLYAVTGYGIAFPKGSKWYSKVNDLIMQYQKYDLLHRWKTFWL 2761
            +L  D + W G      +  P    LRV T+ + PFV    I S  Q    GN  +  S+  D + +S   +      +N T+Y           CC G+AID+L  L         D +F   L+   +  +G   A +      +G++  L     DMA+    I P R   VDFT P+   GI IL           +FL+P   + W  + I SV     A++  ++ SP       D+      + +F L+             A+W +W +L  + V+  +PR  ++R LG +W  F ++ +ASYTANLAAF++  +    L G+ D R + P      F F TV  S   +    +    +++  M  +N     E + +L    +DAFI+DS  LEF AA+   C+LRT G+L+  + YGI   K S W   +   I++  +  ++ +    W+
Sbjct:  374 RLDEDSIEWAGGTKPLEISLPKH--LRVVTVADPPFVYTTPIGSPSQCAELGNTVVEWSIF-DKIVVSGPWYSCPLTLENSTEYF----------CCAGLAIDLLSNLSLPEANNSIDTSFTFSLHL--NESYGVVQASETTGITISGVIGELDGDTADMAIGGITINPERERIVDFTEPWLYHGIRILEKNIPRDSPMQSFLQPLQSSLWTALFI-SVILVGLAIYCLDFKSPFERFYQADKEMEQDLKKEFELWIGKDADENVNFGEAMWFVWGVLLNSGVSEKTPRSCSARVLGIVWCGFCMIMVASYTANLAAFLVLDQPEKGLTGVTDPRLRNP---SANFSFGTVLNSNVYQYFKRHVELSSMFRKMEPHNVRRASEAVHSLLNGSLDAFIWDSTRLEFEAARH--CELRTRGSLFGRSAYGIGLQKNSPWTPHITSAILRMSESGVMEKLDQKWI 814          
BLAST of Glutamate receptor ionotropic, NMDA 2B vs. Ensembl Celegans
Match: glr-4 (GLutamate Receptor family (AMPA) [Source:UniProtKB/TrEMBL;Acc:Q17697])

HSP 1 Score: 143.28 bits (360), Expect = 1.860e-34
Identity = 103/358 (28.77%), Postives = 175/358 (48.88%), Query Frame = 2
Query: 1757 GMAIDILRELMKDLNFEVDLYEVPDRKWGAWSAEKGWNGLLESLINRKVDMAVSAFKITPNRSEQVDFTVPFQETGIAILVA-----LHEGSISPTAFLKPYDWASWMVILIFSVHCCSTAMFI------YEWLSPKGLDR---GNVPPREHKFSLFRALWLIWAMLFGASVNVDSPRGMASRFLGCIWALFGLVFLASYTANLAAFMIAKEDHYDLKGLNDWRFQRPWNFKPEFRFATVPFSASEENIALNYPDIALYMRRYN----------KSSVEEGIRALKQKEIDAFIYDSNVLEFRAAKDEGCKLRTVGNLYAVTGYGIAFPKGSKWYSKVNDLIMQYQKYDLLHRWKTFW 2758
            G  ID+L E+ + L F   + EV D  +G       WNG++ +L   + D+++SA  IT +R+E VDFT+PF   GI+IL+A       +GS+    FL+P     W+ +LI S    S +M I      YEW + + +D     N+  ++++F++  + W     L     +V  PR  A+R +  +W +F  + ++SYTA LAAF+  +     ++   D   Q+   +      +T+ F             I +Y R ++           +S  EGI  +K     A++ +S++LE+   +D  C+L+++G L    GYGIA PKGS     ++  ++Q Q+  +L   K  W
Sbjct:  431 GFCIDLLNEMTQVLKFNYTIIEVQDGTYGIEDESGRWNGIIGALQRHEADLSLSAVTITYSRAEVVDFTLPFMHLGISILLARTSEETDKGSL--WTFLEPLSLTVWISLLI-SYCIVSYSMHILAKFSPYEWYNLERIDERDFENIKNQKNQFTVLNSFWFTMGSLMQQGSDV-IPRAAATRLIAVVWWMFTQIIISSYTAQLAAFLTVERMSTPIESTQDLANQQKIRYGVLKSGSTMDF--------FRESKIPMYERMWSVMESSSPGVFVNSSREGIARVKSGGY-AYMMESSMLEYYLERD--CELQSIGGLLDSKGYGIALPKGSPLRDILSRTVLQLQERTILEALKNKW 773          
BLAST of Glutamate receptor ionotropic, NMDA 2B vs. Ensembl Fly
Match: Nmdar2 (gene:FBgn0053513 transcript:FBtr0091453)

HSP 1 Score: 484.567 bits (1246), Expect = 6.837e-154
Identity = 273/782 (34.91%), Postives = 441/782 (56.39%), Query Frame = 2
Query:  812 LEHILAADHRIILFYGMKYDLIIMHKIALKDPNLSKIFGAEFVWILCPEAITPTMSVMNKKEKFSPSLELSEDMPPLPGVFGFAYAPTTSMLKDNLNIATSFWKTSVEXXXXXXXXXXXXXXXEILERMIPKLNCQSKVDRNDAWTFGKYIYKFMSTLSV--DYNSNFYQFSVHNYLNSTSFLVMNTRSILDKSPLYEMEKEKHFVTSWTKVGTWIMSSTLEEKRTKLQIDGVTWPGEVNKPPLGRPSKFKLRVSTLKEEPFVIFSVKQDKTCG----NNALACSVLHD-SLSISVDDFEKSKNRTKYLYMGNENYTDACCTGMAIDILRELMKDLNFEVDLYEVPDRKWGAWSAEKGWNGLLESLINRKVDMAVSAFKITPNRSEQVDFTVPFQETGIAILVALHEGSISPTAFLKPYDWASWMVILIFSVHCCSTAMFIYEWLSPKGLD------RGNVPPREHKFSLFRALWLIWAMLFGASVNVDSPRGMASRFLGCIWALFGLVFLASYTANLAAFMIAKEDHYDLKGLNDWRFQRPWNFKPEFRFATVPFSASEENIALNYPDIALYMRRYNKSSVEEGIRALKQKEIDAFIYDSNVLEFRAAKDEGCKLRTVGNLYAVTGYGIAFPKGSKWYSKVNDLIMQYQKYDLLHRWKTFWLTGACKKTDKLANTNRTLGVRNFISAFXXXXXXXXXXXXXXXCEHLFFRYLRPRMSNLDQYGCCGLISLSMGQLLSFEQTVNQTVDFVKNYKCHNPLCENQIWRLRKELEMSKEIIRKLE 3118
            L  ++ ++ R++L Y  + + I +    L+     K+ G  +VW++       + SV+ KK+  S         P   G+ G  +  +++ L + ++ A   +   VE  + +   R+    T+        L+C+   +    W  G+  +K++  +S+  D N    +F+    L S    +MN R   +   L            W ++G W    T      KL I  + WPG  + PP G P KF L+++ L+E P++  S   D   G    +  + C V  D  ++  +D  +  +N + Y           CC+G  ID+L +  ++L F  +L  V D KWG     K WNGL+  L+NRK DM +++  I   R   VDF+ PF ETGIAI+VA   G ISPTAFL+P+D ASWM++ I ++   +  +F++EWLSP G D        NV P  ++FSLFR  WL+WA+LF A+V+VDSPRG  SRF+  +WALF +VFLA YTANLAAFMI +E+ ++  GLND R   P++ KP F+F T+P+S ++  I   +  +  YMR+YNK+SV +G+ A+    +D+FIYD  VL++  A+DE C+L TVG+ YA+TGYG+AF + SK+    N  +++++    L R + +W+TG C+   +   ++  L +  F+SAF+LL+ G++++ LLL+ EH++F+Y+R R++  D   CC LISLSMG+ L+F   V +  + +K ++C++P+C+  +W+++ EL+MS+  +R+LE
Sbjct:  118 LMELVNSEARVMLLYATQTEAITI----LRAAEEMKLTGENYVWVV-------SQSVIEKKDAHS-------QFPV--GMLGVHFDTSSAALMNEISNAIKIYSYGVEAYLTDPANRDRRLTTQ-------SLSCED--EGRGRWDNGEIFFKYLRNVSIEGDLNKPNIEFTADGDLRSAELKIMNLRPSANNKNLV-----------WEEIGVWKSWET-----QKLDIRDIAWPGNSHAPPQGVPEKFHLKITFLEEAPYINLS-PADPVSGKCLMDRGVLCRVAADHEMAADIDVGQAHRNESFY----------QCCSGFCIDLLEKFAEELGFTYELVRVEDGKWGTLENGK-WNGLIADLVNRKTDMVLTSLMINTEREAVVDFSEPFMETGIAIVVAKRTGIISPTAFLEPFDTASWMLVGIVAIQAATFMIFLFEWLSPSGYDMKLYLQNTNVTP--YRFSLFRTYWLVWAVLFQAAVHVDSPRGFTSRFMTNVWALFAVVFLAIYTANLAAFMITREEFHEFSGLNDSRLVHPFSHKPSFKFGTIPYSHTDSTIHKYFNVMHNYMRQYNKTSVADGVAAVLNGNLDSFIYDGTVLDYLVAQDEDCRLMTVGSWYAMTGYGLAFSRNSKYVQMFNKRLLEFRANGDLERLRRYWMTGTCRPGKQEHKSSDPLALEQFLSAFLLLMAGILLAALLLLLEHVYFKYIRKRLAKKDGGHCCALISLSMGKSLTFRGAVFEATEILKKHRCNDPICDTHLWKVKHELDMSRLRVRQLE 840          
BLAST of Glutamate receptor ionotropic, NMDA 2B vs. Ensembl Fly
Match: Nmdar2 (gene:FBgn0053513 transcript:FBtr0301842)

HSP 1 Score: 484.567 bits (1246), Expect = 6.837e-154
Identity = 273/782 (34.91%), Postives = 441/782 (56.39%), Query Frame = 2
Query:  812 LEHILAADHRIILFYGMKYDLIIMHKIALKDPNLSKIFGAEFVWILCPEAITPTMSVMNKKEKFSPSLELSEDMPPLPGVFGFAYAPTTSMLKDNLNIATSFWKTSVEXXXXXXXXXXXXXXXEILERMIPKLNCQSKVDRNDAWTFGKYIYKFMSTLSV--DYNSNFYQFSVHNYLNSTSFLVMNTRSILDKSPLYEMEKEKHFVTSWTKVGTWIMSSTLEEKRTKLQIDGVTWPGEVNKPPLGRPSKFKLRVSTLKEEPFVIFSVKQDKTCG----NNALACSVLHD-SLSISVDDFEKSKNRTKYLYMGNENYTDACCTGMAIDILRELMKDLNFEVDLYEVPDRKWGAWSAEKGWNGLLESLINRKVDMAVSAFKITPNRSEQVDFTVPFQETGIAILVALHEGSISPTAFLKPYDWASWMVILIFSVHCCSTAMFIYEWLSPKGLD------RGNVPPREHKFSLFRALWLIWAMLFGASVNVDSPRGMASRFLGCIWALFGLVFLASYTANLAAFMIAKEDHYDLKGLNDWRFQRPWNFKPEFRFATVPFSASEENIALNYPDIALYMRRYNKSSVEEGIRALKQKEIDAFIYDSNVLEFRAAKDEGCKLRTVGNLYAVTGYGIAFPKGSKWYSKVNDLIMQYQKYDLLHRWKTFWLTGACKKTDKLANTNRTLGVRNFISAFXXXXXXXXXXXXXXXCEHLFFRYLRPRMSNLDQYGCCGLISLSMGQLLSFEQTVNQTVDFVKNYKCHNPLCENQIWRLRKELEMSKEIIRKLE 3118
            L  ++ ++ R++L Y  + + I +    L+     K+ G  +VW++       + SV+ KK+  S         P   G+ G  +  +++ L + ++ A   +   VE  + +   R+    T+        L+C+   +    W  G+  +K++  +S+  D N    +F+    L S    +MN R   +   L            W ++G W    T      KL I  + WPG  + PP G P KF L+++ L+E P++  S   D   G    +  + C V  D  ++  +D  +  +N + Y           CC+G  ID+L +  ++L F  +L  V D KWG     K WNGL+  L+NRK DM +++  I   R   VDF+ PF ETGIAI+VA   G ISPTAFL+P+D ASWM++ I ++   +  +F++EWLSP G D        NV P  ++FSLFR  WL+WA+LF A+V+VDSPRG  SRF+  +WALF +VFLA YTANLAAFMI +E+ ++  GLND R   P++ KP F+F T+P+S ++  I   +  +  YMR+YNK+SV +G+ A+    +D+FIYD  VL++  A+DE C+L TVG+ YA+TGYG+AF + SK+    N  +++++    L R + +W+TG C+   +   ++  L +  F+SAF+LL+ G++++ LLL+ EH++F+Y+R R++  D   CC LISLSMG+ L+F   V +  + +K ++C++P+C+  +W+++ EL+MS+  +R+LE
Sbjct:  118 LMELVNSEARVMLLYATQTEAITI----LRAAEEMKLTGENYVWVV-------SQSVIEKKDAHS-------QFPV--GMLGVHFDTSSAALMNEISNAIKIYSYGVEAYLTDPANRDRRLTTQ-------SLSCED--EGRGRWDNGEIFFKYLRNVSIEGDLNKPNIEFTADGDLRSAELKIMNLRPSANNKNLV-----------WEEIGVWKSWET-----QKLDIRDIAWPGNSHAPPQGVPEKFHLKITFLEEAPYINLS-PADPVSGKCLMDRGVLCRVAADHEMAADIDVGQAHRNESFY----------QCCSGFCIDLLEKFAEELGFTYELVRVEDGKWGTLENGK-WNGLIADLVNRKTDMVLTSLMINTEREAVVDFSEPFMETGIAIVVAKRTGIISPTAFLEPFDTASWMLVGIVAIQAATFMIFLFEWLSPSGYDMKLYLQNTNVTP--YRFSLFRTYWLVWAVLFQAAVHVDSPRGFTSRFMTNVWALFAVVFLAIYTANLAAFMITREEFHEFSGLNDSRLVHPFSHKPSFKFGTIPYSHTDSTIHKYFNVMHNYMRQYNKTSVADGVAAVLNGNLDSFIYDGTVLDYLVAQDEDCRLMTVGSWYAMTGYGLAFSRNSKYVQMFNKRLLEFRANGDLERLRRYWMTGTCRPGKQEHKSSDPLALEQFLSAFLLLMAGILLAALLLLLEHVYFKYIRKRLAKKDGGHCCALISLSMGKSLTFRGAVFEATEILKKHRCNDPICDTHLWKVKHELDMSRLRVRQLE 840          
BLAST of Glutamate receptor ionotropic, NMDA 2B vs. Ensembl Fly
Match: Nmdar2 (gene:FBgn0053513 transcript:FBtr0091454)

HSP 1 Score: 484.567 bits (1246), Expect = 6.837e-154
Identity = 273/782 (34.91%), Postives = 441/782 (56.39%), Query Frame = 2
Query:  812 LEHILAADHRIILFYGMKYDLIIMHKIALKDPNLSKIFGAEFVWILCPEAITPTMSVMNKKEKFSPSLELSEDMPPLPGVFGFAYAPTTSMLKDNLNIATSFWKTSVEXXXXXXXXXXXXXXXEILERMIPKLNCQSKVDRNDAWTFGKYIYKFMSTLSV--DYNSNFYQFSVHNYLNSTSFLVMNTRSILDKSPLYEMEKEKHFVTSWTKVGTWIMSSTLEEKRTKLQIDGVTWPGEVNKPPLGRPSKFKLRVSTLKEEPFVIFSVKQDKTCG----NNALACSVLHD-SLSISVDDFEKSKNRTKYLYMGNENYTDACCTGMAIDILRELMKDLNFEVDLYEVPDRKWGAWSAEKGWNGLLESLINRKVDMAVSAFKITPNRSEQVDFTVPFQETGIAILVALHEGSISPTAFLKPYDWASWMVILIFSVHCCSTAMFIYEWLSPKGLD------RGNVPPREHKFSLFRALWLIWAMLFGASVNVDSPRGMASRFLGCIWALFGLVFLASYTANLAAFMIAKEDHYDLKGLNDWRFQRPWNFKPEFRFATVPFSASEENIALNYPDIALYMRRYNKSSVEEGIRALKQKEIDAFIYDSNVLEFRAAKDEGCKLRTVGNLYAVTGYGIAFPKGSKWYSKVNDLIMQYQKYDLLHRWKTFWLTGACKKTDKLANTNRTLGVRNFISAFXXXXXXXXXXXXXXXCEHLFFRYLRPRMSNLDQYGCCGLISLSMGQLLSFEQTVNQTVDFVKNYKCHNPLCENQIWRLRKELEMSKEIIRKLE 3118
            L  ++ ++ R++L Y  + + I +    L+     K+ G  +VW++       + SV+ KK+  S         P   G+ G  +  +++ L + ++ A   +   VE  + +   R+    T+        L+C+   +    W  G+  +K++  +S+  D N    +F+    L S    +MN R   +   L            W ++G W    T      KL I  + WPG  + PP G P KF L+++ L+E P++  S   D   G    +  + C V  D  ++  +D  +  +N + Y           CC+G  ID+L +  ++L F  +L  V D KWG     K WNGL+  L+NRK DM +++  I   R   VDF+ PF ETGIAI+VA   G ISPTAFL+P+D ASWM++ I ++   +  +F++EWLSP G D        NV P  ++FSLFR  WL+WA+LF A+V+VDSPRG  SRF+  +WALF +VFLA YTANLAAFMI +E+ ++  GLND R   P++ KP F+F T+P+S ++  I   +  +  YMR+YNK+SV +G+ A+    +D+FIYD  VL++  A+DE C+L TVG+ YA+TGYG+AF + SK+    N  +++++    L R + +W+TG C+   +   ++  L +  F+SAF+LL+ G++++ LLL+ EH++F+Y+R R++  D   CC LISLSMG+ L+F   V +  + +K ++C++P+C+  +W+++ EL+MS+  +R+LE
Sbjct:  118 LMELVNSEARVMLLYATQTEAITI----LRAAEEMKLTGENYVWVV-------SQSVIEKKDAHS-------QFPV--GMLGVHFDTSSAALMNEISNAIKIYSYGVEAYLTDPANRDRRLTTQ-------SLSCED--EGRGRWDNGEIFFKYLRNVSIEGDLNKPNIEFTADGDLRSAELKIMNLRPSANNKNLV-----------WEEIGVWKSWET-----QKLDIRDIAWPGNSHAPPQGVPEKFHLKITFLEEAPYINLS-PADPVSGKCLMDRGVLCRVAADHEMAADIDVGQAHRNESFY----------QCCSGFCIDLLEKFAEELGFTYELVRVEDGKWGTLENGK-WNGLIADLVNRKTDMVLTSLMINTEREAVVDFSEPFMETGIAIVVAKRTGIISPTAFLEPFDTASWMLVGIVAIQAATFMIFLFEWLSPSGYDMKLYLQNTNVTP--YRFSLFRTYWLVWAVLFQAAVHVDSPRGFTSRFMTNVWALFAVVFLAIYTANLAAFMITREEFHEFSGLNDSRLVHPFSHKPSFKFGTIPYSHTDSTIHKYFNVMHNYMRQYNKTSVADGVAAVLNGNLDSFIYDGTVLDYLVAQDEDCRLMTVGSWYAMTGYGLAFSRNSKYVQMFNKRLLEFRANGDLERLRRYWMTGTCRPGKQEHKSSDPLALEQFLSAFLLLMAGILLAALLLLLEHVYFKYIRKRLAKKDGGHCCALISLSMGKSLTFRGAVFEATEILKKHRCNDPICDTHLWKVKHELDMSRLRVRQLE 840          
BLAST of Glutamate receptor ionotropic, NMDA 2B vs. Ensembl Fly
Match: Nmdar2 (gene:FBgn0053513 transcript:FBtr0301843)

HSP 1 Score: 483.797 bits (1244), Expect = 3.498e-153
Identity = 273/782 (34.91%), Postives = 441/782 (56.39%), Query Frame = 2
Query:  812 LEHILAADHRIILFYGMKYDLIIMHKIALKDPNLSKIFGAEFVWILCPEAITPTMSVMNKKEKFSPSLELSEDMPPLPGVFGFAYAPTTSMLKDNLNIATSFWKTSVEXXXXXXXXXXXXXXXEILERMIPKLNCQSKVDRNDAWTFGKYIYKFMSTLSV--DYNSNFYQFSVHNYLNSTSFLVMNTRSILDKSPLYEMEKEKHFVTSWTKVGTWIMSSTLEEKRTKLQIDGVTWPGEVNKPPLGRPSKFKLRVSTLKEEPFVIFSVKQDKTCG----NNALACSVLHD-SLSISVDDFEKSKNRTKYLYMGNENYTDACCTGMAIDILRELMKDLNFEVDLYEVPDRKWGAWSAEKGWNGLLESLINRKVDMAVSAFKITPNRSEQVDFTVPFQETGIAILVALHEGSISPTAFLKPYDWASWMVILIFSVHCCSTAMFIYEWLSPKGLD------RGNVPPREHKFSLFRALWLIWAMLFGASVNVDSPRGMASRFLGCIWALFGLVFLASYTANLAAFMIAKEDHYDLKGLNDWRFQRPWNFKPEFRFATVPFSASEENIALNYPDIALYMRRYNKSSVEEGIRALKQKEIDAFIYDSNVLEFRAAKDEGCKLRTVGNLYAVTGYGIAFPKGSKWYSKVNDLIMQYQKYDLLHRWKTFWLTGACKKTDKLANTNRTLGVRNFISAFXXXXXXXXXXXXXXXCEHLFFRYLRPRMSNLDQYGCCGLISLSMGQLLSFEQTVNQTVDFVKNYKCHNPLCENQIWRLRKELEMSKEIIRKLE 3118
            L  ++ ++ R++L Y  + + I +    L+     K+ G  +VW++       + SV+ KK+  S         P   G+ G  +  +++ L + ++ A   +   VE  + +   R+    T+        L+C+   +    W  G+  +K++  +S+  D N    +F+    L S    +MN R   +   L            W ++G W    T      KL I  + WPG  + PP G P KF L+++ L+E P++  S   D   G    +  + C V  D  ++  +D  +  +N + Y           CC+G  ID+L +  ++L F  +L  V D KWG     K WNGL+  L+NRK DM +++  I   R   VDF+ PF ETGIAI+VA   G ISPTAFL+P+D ASWM++ I ++   +  +F++EWLSP G D        NV P  ++FSLFR  WL+WA+LF A+V+VDSPRG  SRF+  +WALF +VFLA YTANLAAFMI +E+ ++  GLND R   P++ KP F+F T+P+S ++  I   +  +  YMR+YNK+SV +G+ A+    +D+FIYD  VL++  A+DE C+L TVG+ YA+TGYG+AF + SK+    N  +++++    L R + +W+TG C+   +   ++  L +  F+SAF+LL+ G++++ LLL+ EH++F+Y+R R++  D   CC LISLSMG+ L+F   V +  + +K ++C++P+C+  +W+++ EL+MS+  +R+LE
Sbjct:  157 LMELVNSEARVMLLYATQTEAITI----LRAAEEMKLTGENYVWVV-------SQSVIEKKDAHS-------QFPV--GMLGVHFDTSSAALMNEISNAIKIYSYGVEAYLTDPANRDRRLTTQ-------SLSCED--EGRGRWDNGEIFFKYLRNVSIEGDLNKPNIEFTADGDLRSAELKIMNLRPSANNKNLV-----------WEEIGVWKSWET-----QKLDIRDIAWPGNSHAPPQGVPEKFHLKITFLEEAPYINLS-PADPVSGKCLMDRGVLCRVAADHEMAADIDVGQAHRNESFY----------QCCSGFCIDLLEKFAEELGFTYELVRVEDGKWGTLENGK-WNGLIADLVNRKTDMVLTSLMINTEREAVVDFSEPFMETGIAIVVAKRTGIISPTAFLEPFDTASWMLVGIVAIQAATFMIFLFEWLSPSGYDMKLYLQNTNVTP--YRFSLFRTYWLVWAVLFQAAVHVDSPRGFTSRFMTNVWALFAVVFLAIYTANLAAFMITREEFHEFSGLNDSRLVHPFSHKPSFKFGTIPYSHTDSTIHKYFNVMHNYMRQYNKTSVADGVAAVLNGNLDSFIYDGTVLDYLVAQDEDCRLMTVGSWYAMTGYGLAFSRNSKYVQMFNKRLLEFRANGDLERLRRYWMTGTCRPGKQEHKSSDPLALEQFLSAFLLLMAGILLAALLLLLEHVYFKYIRKRLAKKDGGHCCALISLSMGKSLTFRGAVFEATEILKKHRCNDPICDTHLWKVKHELDMSRLRVRQLE 879          
BLAST of Glutamate receptor ionotropic, NMDA 2B vs. Ensembl Fly
Match: Nmdar2 (gene:FBgn0053513 transcript:FBtr0301844)

HSP 1 Score: 485.723 bits (1249), Expect = 1.935e-152
Identity = 273/782 (34.91%), Postives = 441/782 (56.39%), Query Frame = 2
Query:  812 LEHILAADHRIILFYGMKYDLIIMHKIALKDPNLSKIFGAEFVWILCPEAITPTMSVMNKKEKFSPSLELSEDMPPLPGVFGFAYAPTTSMLKDNLNIATSFWKTSVEXXXXXXXXXXXXXXXEILERMIPKLNCQSKVDRNDAWTFGKYIYKFMSTLSV--DYNSNFYQFSVHNYLNSTSFLVMNTRSILDKSPLYEMEKEKHFVTSWTKVGTWIMSSTLEEKRTKLQIDGVTWPGEVNKPPLGRPSKFKLRVSTLKEEPFVIFSVKQDKTCG----NNALACSVLHD-SLSISVDDFEKSKNRTKYLYMGNENYTDACCTGMAIDILRELMKDLNFEVDLYEVPDRKWGAWSAEKGWNGLLESLINRKVDMAVSAFKITPNRSEQVDFTVPFQETGIAILVALHEGSISPTAFLKPYDWASWMVILIFSVHCCSTAMFIYEWLSPKGLD------RGNVPPREHKFSLFRALWLIWAMLFGASVNVDSPRGMASRFLGCIWALFGLVFLASYTANLAAFMIAKEDHYDLKGLNDWRFQRPWNFKPEFRFATVPFSASEENIALNYPDIALYMRRYNKSSVEEGIRALKQKEIDAFIYDSNVLEFRAAKDEGCKLRTVGNLYAVTGYGIAFPKGSKWYSKVNDLIMQYQKYDLLHRWKTFWLTGACKKTDKLANTNRTLGVRNFISAFXXXXXXXXXXXXXXXCEHLFFRYLRPRMSNLDQYGCCGLISLSMGQLLSFEQTVNQTVDFVKNYKCHNPLCENQIWRLRKELEMSKEIIRKLE 3118
            L  ++ ++ R++L Y  + + I +    L+     K+ G  +VW++       + SV+ KK+  S         P   G+ G  +  +++ L + ++ A   +   VE  + +   R+    T+        L+C+   +    W  G+  +K++  +S+  D N    +F+    L S    +MN R   +   L            W ++G W    T      KL I  + WPG  + PP G P KF L+++ L+E P++  S   D   G    +  + C V  D  ++  +D  +  +N + Y           CC+G  ID+L +  ++L F  +L  V D KWG     K WNGL+  L+NRK DM +++  I   R   VDF+ PF ETGIAI+VA   G ISPTAFL+P+D ASWM++ I ++   +  +F++EWLSP G D        NV P  ++FSLFR  WL+WA+LF A+V+VDSPRG  SRF+  +WALF +VFLA YTANLAAFMI +E+ ++  GLND R   P++ KP F+F T+P+S ++  I   +  +  YMR+YNK+SV +G+ A+    +D+FIYD  VL++  A+DE C+L TVG+ YA+TGYG+AF + SK+    N  +++++    L R + +W+TG C+   +   ++  L +  F+SAF+LL+ G++++ LLL+ EH++F+Y+R R++  D   CC LISLSMG+ L+F   V +  + +K ++C++P+C+  +W+++ EL+MS+  +R+LE
Sbjct:  299 LMELVNSEARVMLLYATQTEAITI----LRAAEEMKLTGENYVWVV-------SQSVIEKKDAHS-------QFPV--GMLGVHFDTSSAALMNEISNAIKIYSYGVEAYLTDPANRDRRLTTQ-------SLSCED--EGRGRWDNGEIFFKYLRNVSIEGDLNKPNIEFTADGDLRSAELKIMNLRPSANNKNLV-----------WEEIGVWKSWET-----QKLDIRDIAWPGNSHAPPQGVPEKFHLKITFLEEAPYINLS-PADPVSGKCLMDRGVLCRVAADHEMAADIDVGQAHRNESFY----------QCCSGFCIDLLEKFAEELGFTYELVRVEDGKWGTLENGK-WNGLIADLVNRKTDMVLTSLMINTEREAVVDFSEPFMETGIAIVVAKRTGIISPTAFLEPFDTASWMLVGIVAIQAATFMIFLFEWLSPSGYDMKLYLQNTNVTP--YRFSLFRTYWLVWAVLFQAAVHVDSPRGFTSRFMTNVWALFAVVFLAIYTANLAAFMITREEFHEFSGLNDSRLVHPFSHKPSFKFGTIPYSHTDSTIHKYFNVMHNYMRQYNKTSVADGVAAVLNGNLDSFIYDGTVLDYLVAQDEDCRLMTVGSWYAMTGYGLAFSRNSKYVQMFNKRLLEFRANGDLERLRRYWMTGTCRPGKQEHKSSDPLALEQFLSAFLLLMAGILLAALLLLLEHVYFKYIRKRLAKKDGGHCCALISLSMGKSLTFRGAVFEATEILKKHRCNDPICDTHLWKVKHELDMSRLRVRQLE 1021          
BLAST of Glutamate receptor ionotropic, NMDA 2B vs. Ensembl Zebrafish
Match: grin2cb (glutamate receptor, ionotropic, N-methyl D-aspartate 2Cb [Source:ZFIN;Acc:ZDB-GENE-100308-2])

HSP 1 Score: 333.954 bits (855), Expect = 2.992e-95
Identity = 216/648 (33.33%), Postives = 338/648 (52.16%), Query Frame = 2
Query: 1271 FMSTLSVDYNSNFYQFSVHNYLNSTSFLVMNTRSILDKSPLYEMEKEKHFVTSWTKVGTWIMSSTLEEKRTKLQIDGVTWP--GEVNKPPLGRPSKFKLRVSTLKEEPFVIFSV--KQDKTCGNNALACSVLHDSLSISVDDFEKSKNRTKYLYMGNENYTDACCTGMAIDILRELMKDLNFEVDLYEVPDRKWGAWSAEKGWNGLLESLINRKVDMAVSAFKITPNRSEQVDFTVPFQETGIAILVALHEGSISPTAFLKPYDWASWMVILIFSVHCCSTAMFIYEWLSPKGLDRGNV---PPREHKFSLFRALWLIWAMLFGASVNVDSPRGMASRFLGCIWALFGLVFLASYTANLAAFMIAKEDHYDLKGLNDWRFQRPWNFKPEFRFATVPFSASEENIALNYPDIALYMRRYNKSSVEEGIRALKQKEIDAFIYDSNVLEFRAAKDEGCKLRTVGN--LYAVTGYGIAFPKGSKWYSKVNDLIMQYQKYDLLHRWKTFWLTGACKKTDKLANTNRTLGVRNFISAFXXXXXXXXXXXXXXXCEHLFFRYLRPRMSNLDQYGCCGLISLSMGQLLSF-------EQTVNQTVDFVKNYKCHNPLCENQIWRLRKELEMSKEIIR--KLETSFEGLNSSLRSMS 3160
            F   L+V +      F+   YL + S +++             +++E H    W KVG++        +   LQ+    WP  G   +P         L V+TL+E PFVI         TC  N + C               +  NRT+ +    E YT  CC G  IDIL++L + + F  DLY V + K G       WNG++  +  ++ DMA+ +  I   RSE VDF+VPF ETGI+++VA   G++SP+AFL+PY  A W+++ +  +   +  +F++E+ SP G +R  V    P    F++ +++WL+W ++F  SV +++P+G  S+ +  +WA F ++FLASYTANLAAFMI ++    + GL+D +FQ+P    P FRF TVP  ++E NI  NYPD+  +M +YN+  VEE + +LK  ++DAFIYD+ VL + A KDEGCKL T+G+  ++A TGYGIA  K S+W   ++  ++Q+       R +T WL+G C+  +K    +  L + N    F +LL  + +S L+   EHL +  LR  +   D+     L+++S G    F         T  Q  D   NY   N L         K L+ +K+I+   K+E S +    ++ + S
Sbjct:  339 FRHMLNVSWEHKDLSFNSDGYLTNPSMVII------------ALDRENH----WDKVGSY--------EGGILQMRYPVWPRYGSFLEP---VSDNRHLTVATLEERPFVIVESVDPATGTCVRNTVPC--------------RRQSNRTESIIGHTEPYTKLCCKGFCIDILKKLSRTIKFSYDLYLVTNGKHGKM-VRGVWNGMIGEVFYKRADMAIGSLTINEERSEIVDFSVPFVETGISVMVARSNGTVSPSAFLEPYSPAVWVMMFVMCLTVVAVTVFVFEYFSPVGYNRSLVSAKAPGGPTFTIGKSVWLLWGIVFNNSVPIENPKGTTSKIMVLVWAFFAVIFLASYTANLAAFMIQEQYIDTVSGLSDKKFQKPQEHYPPFRFGTVPNGSTERNIRSNYPDMHTHMIKYNQKGVEEALNSLKTGKLDAFIYDAAVLNYMAGKDEGCKLVTIGSGKVFATTGYGIALQKDSRWKRPIDLALLQFLGDGDTQRLETVWLSGICQN-EKNEVMSSKLDIDNMAGVFYMLLVAMGLSLLVFAWEHLLYWKLRHSVHKSDRLDF--LLAISRGIYSCFNGVEDIGRSTGIQNPDITANYAQANML---------KMLQTAKDIVSSAKVENSLDNATKTIENWS 932          
BLAST of Glutamate receptor ionotropic, NMDA 2B vs. Ensembl Zebrafish
Match: grin2cb (glutamate receptor, ionotropic, N-methyl D-aspartate 2Cb [Source:ZFIN;Acc:ZDB-GENE-100308-2])

HSP 1 Score: 333.954 bits (855), Expect = 2.992e-95
Identity = 216/648 (33.33%), Postives = 338/648 (52.16%), Query Frame = 2
Query: 1271 FMSTLSVDYNSNFYQFSVHNYLNSTSFLVMNTRSILDKSPLYEMEKEKHFVTSWTKVGTWIMSSTLEEKRTKLQIDGVTWP--GEVNKPPLGRPSKFKLRVSTLKEEPFVIFSV--KQDKTCGNNALACSVLHDSLSISVDDFEKSKNRTKYLYMGNENYTDACCTGMAIDILRELMKDLNFEVDLYEVPDRKWGAWSAEKGWNGLLESLINRKVDMAVSAFKITPNRSEQVDFTVPFQETGIAILVALHEGSISPTAFLKPYDWASWMVILIFSVHCCSTAMFIYEWLSPKGLDRGNV---PPREHKFSLFRALWLIWAMLFGASVNVDSPRGMASRFLGCIWALFGLVFLASYTANLAAFMIAKEDHYDLKGLNDWRFQRPWNFKPEFRFATVPFSASEENIALNYPDIALYMRRYNKSSVEEGIRALKQKEIDAFIYDSNVLEFRAAKDEGCKLRTVGN--LYAVTGYGIAFPKGSKWYSKVNDLIMQYQKYDLLHRWKTFWLTGACKKTDKLANTNRTLGVRNFISAFXXXXXXXXXXXXXXXCEHLFFRYLRPRMSNLDQYGCCGLISLSMGQLLSF-------EQTVNQTVDFVKNYKCHNPLCENQIWRLRKELEMSKEIIR--KLETSFEGLNSSLRSMS 3160
            F   L+V +      F+   YL + S +++             +++E H    W KVG++        +   LQ+    WP  G   +P         L V+TL+E PFVI         TC  N + C               +  NRT+ +    E YT  CC G  IDIL++L + + F  DLY V + K G       WNG++  +  ++ DMA+ +  I   RSE VDF+VPF ETGI+++VA   G++SP+AFL+PY  A W+++ +  +   +  +F++E+ SP G +R  V    P    F++ +++WL+W ++F  SV +++P+G  S+ +  +WA F ++FLASYTANLAAFMI ++    + GL+D +FQ+P    P FRF TVP  ++E NI  NYPD+  +M +YN+  VEE + +LK  ++DAFIYD+ VL + A KDEGCKL T+G+  ++A TGYGIA  K S+W   ++  ++Q+       R +T WL+G C+  +K    +  L + N    F +LL  + +S L+   EHL +  LR  +   D+     L+++S G    F         T  Q  D   NY   N L         K L+ +K+I+   K+E S +    ++ + S
Sbjct:  339 FRHMLNVSWEHKDLSFNSDGYLTNPSMVII------------ALDRENH----WDKVGSY--------EGGILQMRYPVWPRYGSFLEP---VSDNRHLTVATLEERPFVIVESVDPATGTCVRNTVPC--------------RRQSNRTESIIGHTEPYTKLCCKGFCIDILKKLSRTIKFSYDLYLVTNGKHGKM-VRGVWNGMIGEVFYKRADMAIGSLTINEERSEIVDFSVPFVETGISVMVARSNGTVSPSAFLEPYSPAVWVMMFVMCLTVVAVTVFVFEYFSPVGYNRSLVSAKAPGGPTFTIGKSVWLLWGIVFNNSVPIENPKGTTSKIMVLVWAFFAVIFLASYTANLAAFMIQEQYIDTVSGLSDKKFQKPQEHYPPFRFGTVPNGSTERNIRSNYPDMHTHMIKYNQKGVEEALNSLKTGKLDAFIYDAAVLNYMAGKDEGCKLVTIGSGKVFATTGYGIALQKDSRWKRPIDLALLQFLGDGDTQRLETVWLSGICQN-EKNEVMSSKLDIDNMAGVFYMLLVAMGLSLLVFAWEHLLYWKLRHSVHKSDRLDF--LLAISRGIYSCFNGVEDIGRSTGIQNPDITANYAQANML---------KMLQTAKDIVSSAKVENSLDNATKTIENWS 932          
BLAST of Glutamate receptor ionotropic, NMDA 2B vs. Ensembl Zebrafish
Match: BX294659.1 (glutamate receptor, ionotropic, N-methyl D-aspartate 2Cb [Source:NCBI gene;Acc:100333648])

HSP 1 Score: 333.954 bits (855), Expect = 3.836e-95
Identity = 216/648 (33.33%), Postives = 338/648 (52.16%), Query Frame = 2
Query: 1271 FMSTLSVDYNSNFYQFSVHNYLNSTSFLVMNTRSILDKSPLYEMEKEKHFVTSWTKVGTWIMSSTLEEKRTKLQIDGVTWP--GEVNKPPLGRPSKFKLRVSTLKEEPFVIFSV--KQDKTCGNNALACSVLHDSLSISVDDFEKSKNRTKYLYMGNENYTDACCTGMAIDILRELMKDLNFEVDLYEVPDRKWGAWSAEKGWNGLLESLINRKVDMAVSAFKITPNRSEQVDFTVPFQETGIAILVALHEGSISPTAFLKPYDWASWMVILIFSVHCCSTAMFIYEWLSPKGLDRGNV---PPREHKFSLFRALWLIWAMLFGASVNVDSPRGMASRFLGCIWALFGLVFLASYTANLAAFMIAKEDHYDLKGLNDWRFQRPWNFKPEFRFATVPFSASEENIALNYPDIALYMRRYNKSSVEEGIRALKQKEIDAFIYDSNVLEFRAAKDEGCKLRTVGN--LYAVTGYGIAFPKGSKWYSKVNDLIMQYQKYDLLHRWKTFWLTGACKKTDKLANTNRTLGVRNFISAFXXXXXXXXXXXXXXXCEHLFFRYLRPRMSNLDQYGCCGLISLSMGQLLSF-------EQTVNQTVDFVKNYKCHNPLCENQIWRLRKELEMSKEIIR--KLETSFEGLNSSLRSMS 3160
            F   L+V +      F+   YL + S +++             +++E H    W KVG++        +   LQ+    WP  G   +P         L V+TL+E PFVI         TC  N + C               +  NRT+ +    E YT  CC G  IDIL++L + + F  DLY V + K G       WNG++  +  ++ DMA+ +  I   RSE VDF+VPF ETGI+++VA   G++SP+AFL+PY  A W+++ +  +   +  +F++E+ SP G +R  V    P    F++ +++WL+W ++F  SV +++P+G  S+ +  +WA F ++FLASYTANLAAFMI ++    + GL+D +FQ+P    P FRF TVP  ++E NI  NYPD+  +M +YN+  VEE + +LK  ++DAFIYD+ VL + A KDEGCKL T+G+  ++A TGYGIA  K S+W   ++  ++Q+       R +T WL+G C+  +K    +  L + N    F +LL  + +S L+   EHL +  LR  +   D+     L+++S G    F         T  Q  D   NY   N L         K L+ +K+I+   K+E S +    ++ + S
Sbjct:  339 FRHMLNVSWEHKDLSFNSDGYLTNPSMVII------------ALDRENH----WDKVGSY--------EGGILQMRYPVWPRYGSFLEP---VSDNRHLTVATLEERPFVIVESVDPATGTCVRNTVPC--------------RRQSNRTESIIGHTEPYTKLCCKGFCIDILKKLSRTIKFSYDLYLVTNGKHGKM-VRGVWNGMIGEVFYKRADMAIGSLTINEERSEIVDFSVPFVETGISVMVARSNGTVSPSAFLEPYSPAVWVMMFVMCLTVVAVTVFVFEYFSPVGYNRSLVSAKAPGGPTFTIGKSVWLLWGIVFNNSVPIENPKGTTSKIMVLVWAFFAVIFLASYTANLAAFMIQEQYIDTVSGLSDKKFQKPQEHYPPFRFGTVPNGSTERNIRSNYPDMHTHMIKYNQKGVEEALNSLKTGKLDAFIYDAAVLNYMAGKDEGCKLVTIGSGKVFATTGYGIALQKDSRWKRPIDLALLQFLGDGDTQRLETVWLSGICQN-EKNEVMSSKLDIDNMAGVFYMLLVAMGLSLLVFAWEHLLYWKLRHSVHKSDRLDF--LLAISRGIYSCFNGVEDIGRSTGIQNPDITANYAQANML---------KMLQTAKDIVSSAKVENSLDNATKTIENWS 932          
BLAST of Glutamate receptor ionotropic, NMDA 2B vs. Ensembl Zebrafish
Match: grin2aa (glutamate receptor, ionotropic, N-methyl D-aspartate 2A, a [Source:ZFIN;Acc:ZDB-GENE-070424-129])

HSP 1 Score: 327.02 bits (837), Expect = 2.115e-92
Identity = 187/531 (35.22%), Postives = 290/531 (54.61%), Query Frame = 2
Query: 1430 WTKVGTWIMSSTLEEKRTKLQIDGVTWPGEVNKPPLGRPSKFKLRVSTLKEEPFVIFS--VKQDKTCGNNALACSVLHDSLSISVDDFEKSKNRTKYLYMGNENYTDACCTGMAIDILRELMKDLNFEVDLYEVPDRKWGAWSAEKGWNGLLESLINRKVDMAVSAFKITPNRSEQVDFTVPFQETGIAILVALHEGSISPTAFLKPYDWASWMVILIFSVHCCSTAMFIYEWLSPKGLDRG---NVPPREHKFSLFRALWLIWAMLFGASVNVDSPRGMASRFLGCIWALFGLVFLASYTANLAAFMIAKEDHYDLKGLNDWRFQRPWNFKPEFRFATVPFSASEENIALNYPDIALYMRRYNKSSVEEGIRALKQKEIDAFIYDSNVLEFRAAKDEGCKLRTVGN--LYAVTGYGIAFPKGSKWYSKVNDLIMQYQKYDLLHRWKTFWLTGACKKTDKLANTNRTLGVRNFISAFXXXXXXXXXXXXXXXCEHLFFRYLRPRMSNLDQYGCCGLISLSMGQLLSFEQTV 3001
            W K+G W        +   L +    WP   N           L + TL+E+PFVI     +   TC  N++ C                 K+       G   Y   CC G  IDIL+++ +++ F  DLY V + K G       WNG++  ++N+K  MAV +  I   RSE +DF+VPF ETGI+++V+   G++SP+AFL+P+  + W+++ +  +   + A+F++E++SP G +R       P    F++ +A+WL+W ++F  SV V +P+G  S+F+  +WA F ++FLASYTANLAAFMI +E    + GL+D +FQ P+++ P FRF TVP  ++E NI  NYPD+  YM +Y+++ V + + +LK  ++DAFIYD+ VL + A +DEGCKL T+G+  ++A TGYGIA  KGS W   V+  I+       +   +  WLTG C   +K    +  L V N    F +L T + +S +  + EHLF+  LR        Y   G+ S + G L S  + +
Sbjct:  369 WEKMGKW--------ENQSLTLKYPVWP-RFNSFGDAETDDNHLTIVTLEEKPFVIVENVERLTGTCMRNSVPCR----------------KHIKDNTTEGGGTYIKKCCKGFCIDILKKIARNVKFTYDLYLVTNGKHGK-KINNVWNGMVGEVVNKKAVMAVGSLTINEERSEVIDFSVPFVETGISVMVSRSNGTVSPSAFLEPFSASVWVMMFVMLLLVTAMAVFMFEYISPLGFNRNLAQGKDPHGPSFTMGKAVWLLWGLVFNNSVPVQNPKGTTSKFIVSVWAFFAVIFLASYTANLAAFMIQEEFVDQVTGLSDKKFQSPYSYSPPFRFGTVPNGSTERNIRKNYPDMHQYMVKYHQTGVNDALVSLKTGKLDAFIYDAAVLNYMAGRDEGCKLVTIGSGYIFATTGYGIALQKGSLWKRPVDLAILAIIGDGEMEELEAQWLTGIC-HNEKNEVMSSQLDVDNMAGVFYMLATAMGLSLITFVWEHLFYWRLR--------YCFTGVCSGTPGLLFSISRGI 864          
BLAST of Glutamate receptor ionotropic, NMDA 2B vs. Ensembl Zebrafish
Match: grin2db (glutamate receptor, ionotropic, N-methyl D-aspartate 2D, b [Source:ZFIN;Acc:ZDB-GENE-100920-7])

HSP 1 Score: 320.087 bits (819), Expect = 4.298e-92
Identity = 192/538 (35.69%), Postives = 295/538 (54.83%), Query Frame = 2
Query: 1424 TSWTKVGTWIMSSTLEEKRTKLQIDGVTWPGEVNKPPLGRPSKFKLRVSTLKEEPFVIFSVKQ--DKTCGNNALACSVLHDSLSISVDDFEKSKNRTKYLYMGNENYTDACCTGMAIDILRELMKDLNFEVDLYEVPDRKWGAWSAEKGWNGLLESLINRKVDMAVSAFKITPNRSEQVDFTVPFQETGIAILVALHEGSISPTAFLKPYDWASWMVILIFSVHCCSTAMFIYEWLSPKGLDRGNVPPRE---HKFSLFRALWLIWAMLFGASVNVDSPRGMASRFLGCIWALFGLVFLASYTANLAAFMIAKEDHYDLKGLNDWRFQRPWNFKPEFRFATVPFSASEENIALNYPDIALYMRRYNKSSVEEGIRALKQKEIDAFIYDSNVLEFRAAKDEGCKLRTVGN--LYAVTGYGIAFPKGSKWYSKVNDLIMQYQKYDLLHRWKTFWLTGACKKTDKLANTNRTLGVRNFISAFXXXXXXXXXXXXXXXCEHLFFRYLRPRMSNLDQYGCCGLI---SLSMGQLLSFEQTVNQ 3007
            + W  VG W      E    +L+    +  G   +PP        LRV TL+E PFVI  +      TC  +++ C        ++    ++     K            CC G  IDIL+ L + + F  DLY V + K G    +  WNG++  ++ ++ DMA+ +  I   RSE VDF+VPF ETGI+++V+   G++SP+AFL+PY  A W+++ +  +   +  +FI+E+ SP G +R     ++    KF++ +++WL+WA++F  SV V++P+G  S+ +  +WA F ++FLASYTANLAAFMI +E    + GL+D +FQ P    P  +F TVP  ++E+NI  NYPD+  YM +YN+ SVE+ I  LK  ++DAFIYD+ VL + A KDEGCK+ T+G+  ++A TGYGIA  K S+W   ++  ++Q    D +   +  WL+G C   DK+   +  L + N    F +LL  + +S L+   EHL +  LR  MS + Q G    +   S  M    SFE    Q
Sbjct:  399 SGWEDVGWW------ENGVLRLRYPAWSRYGPFLQPP---DDAQHLRVVTLEERPFVIVELADAASGTCIRDSVPC-----RRPLNASALQEGVAPVK-----------QCCKGFCIDILKRLARIVGFTYDLYLVTNGKHGK-KIDGVWNGMVGEVVYKRADMAIGSLTINEERSEVVDFSVPFVETGISVMVSRSNGTVSPSAFLEPYSPAVWVMMFVMCLTVVAVTVFIFEFFSPVGYNRSLQSGKKAGGSKFTIGKSIWLLWALVFNNSVPVENPKGTTSKIMVLVWAFFAVIFLASYTANLAAFMIQEEYIDTVSGLSDKKFQHPTEQYPPLKFGTVPNGSTEKNIRSNYPDMHQYMVKYNQKSVEDAISHLKTGKLDAFIYDAAVLNYMARKDEGCKVMTIGSGKVFATTGYGIALIKNSRWKRPLDLALLQLVGDDEIEMLERLWLSGICHN-DKIEVMSSKLDIDNMAGVFYMLLVAMGLSLLVFAWEHLVYWRLRHCMSKMGQSGKLDFLLAFSRGMYSCCSFEDETAQ 909          
BLAST of Glutamate receptor ionotropic, NMDA 2B vs. Ensembl Xenopus
Match: sdr42e1 (short chain dehydrogenase/reductase family 42E, member 1 [Source:Xenbase;Acc:XB-GENE-985965])

HSP 1 Score: 330.872 bits (847), Expect = 8.982e-97
Identity = 191/511 (37.38%), Postives = 292/511 (57.14%), Query Frame = 2
Query: 1559 LRVSTLKEEPFVIFSV--KQDKTCGNNALACSVLHDSLSISVDDFEKSKNRTKYLYMGNENYTDACCTGMAIDILRELMKDLNFEVDLYEVPDRKWGAWSAEKGWNGLLESLINRKVDMAVSAFKITPNRSEQVDFTVPFQETGIAILVALHEGSISPTAFLKPYDWASWMVILIFSVHCCSTAMFIYEWLSPKGLDRG---NVPPREHKFSLFRALWLIWAMLFGASVNVDSPRGMASRFLGCIWALFGLVFLASYTANLAAFMIAKEDHYDLKGLNDWRFQRPWNFKPEFRFATVPFSASEENIALNYPDIALYMRRYNKSSVEEGIRALKQKEIDAFIYDSNVLEFRAAKDEGCKLRTVGN--LYAVTGYGIAFPKGSKWYSKVNDLIMQYQKYDLLHRWKTFWLTGACKKTDKLANTNRTLGVRNFISAFXXXXXXXXXXXXXXXCEHLFFRYLRPRMSNLDQYGCCGLISLSMGQLLSFE--QTVNQTVDFVKNYKCHNPLCENQI 3064
            L V+TL+E PFVI         TC  +++ C               K  NRT         +   CC G  IDIL+ L K + F  DLY V + K G    +  WNG++  +  ++ DMA+ +  I   RSE +DF+VPF ETGI+++V+   G++SP+AFL+PY  A W+++ +  +   +  +FI+E+ SP G +R       P   KF++ +++WL+WA++F  SV V++P+G  S+ +  IWA F ++FLASYTANLAAFMI +E    + GL+D +FQRP    P  +F TVP  ++E+NI  NYPD+  YM +YN+  VE+ ++ LK  ++DAFIYD+ VL + A KDEGCKL T+G+  ++A TGYGIA  KGSKW   ++  ++Q+   D +   +  WL+G C   DK+   +  L + N    F +LL  + +S L+   EHL +  LR  M +          S  +  LL+F   +T+ Q V F+K+ + +   C+ +I
Sbjct:  395 LTVATLEERPFVIVEGVDPATGTCIRDSVPC--------------RKQLNRTDNHLTDPIIFVKQCCKGFCIDILKRLSKTIGFTYDLYLVTNGKHGK-KIDGVWNGMIGEVFYQRADMAIGSLTINEERSEIIDFSVPFVETGISVMVSRSNGTVSPSAFLEPYSPAVWVMMFVMCLTVVAVTVFIFEYFSPVGYNRSLSTGKRPGGSKFTIGKSIWLLWALVFNNSVPVENPKGTTSKIMVLIWAFFAVIFLASYTANLAAFMIQEEYVDTVSGLSDKKFQRPHEQYPPLKFGTVPNGSTEKNIRSNYPDMHAYMIKYNQRHVEDALQNLKTGKLDAFIYDAAVLNYMARKDEGCKLVTIGSGKVFATTGYGIALQKGSKWKRPIDLALLQFLGDDEIEMLERLWLSGICHN-DKIEVMSSKLDIDNMAGVFYMLLVAMGLSLLVFAWEHLIYWKLRHCMRH----------SGKLDFLLAFSRVKTIFQFVVFLKHIEVNVICCKWKI 879          
BLAST of Glutamate receptor ionotropic, NMDA 2B vs. Ensembl Xenopus
Match: GRIN2C (glutamate receptor, ionotropic, N-methyl D-aspartate 2C [Source:NCBI gene;Acc:100496638])

HSP 1 Score: 331.257 bits (848), Expect = 7.924e-95
Identity = 189/483 (39.13%), Postives = 277/483 (57.35%), Query Frame = 2
Query: 1559 LRVSTLKEEPFVIFSVKQDKT--CGNNALACSVLHDSLSISVDDFEKSKNRTKYLYMGNENYTDACCTGMAIDILRELMKDLNFEVDLYEVPDRKWGAWSAEKGWNGLLESLINRKVDMAVSAFKITPNRSEQVDFTVPFQETGIAILVALHEGSISPTAFLKPYDWASWMVILIFSVHCCSTAMFIYEWLSPKGLD-------RGNVPPREHKFSLFRALWLIWAMLFGASVNVDSPRGMASRFLGCIWALFGLVFLASYTANLAAFMIAKEDHYDLKGLNDWRFQRPWNFKPEFRFATVPFSASEENIALNYPDIALYMRRYNKSSVEEGIRALKQKEIDAFIYDSNVLEFRAAKDEGCKLRTVGN--LYAVTGYGIAFPKGSKWYSKVNDLIMQYQKYDLLHRWKTFWLTGACKKTDKLANTNRTLGVRNFISAFXXXXXXXXXXXXXXXCEHLFFRYLRPRMSNLDQYGCCGLISLSMG 2974
            L V+TL+E PFVI       T  C  N + C               K  N T  L    E YT  CC G  IDIL++L + + F  DLY V + K G       WNG++  +  R+  +A+ +  I   RSE VDF+VPF ETGI++LV+   G++SP+AFL+PY  A WM++ +  +   +  +FI+E+ SP G D       R   P     F++ ++LWL+WA++F  SV + +PRG  S+ +  +WA F ++FLASYTANLAAFMI ++    + GL+D +FQ+P    P FRF TVP  ++E NI  NYPD+  YM RYN+ SVE+ + +LK  ++DAFIYD+ VL + A KDEGCKL T+G+  ++A TGYGIA  K S+W   ++  ++Q+       R +T WL+G C+     A +++ L + N    F +LL  + +S L+   EHL +  +R  M +    G  GL+ +S G
Sbjct:  388 LTVATLEERPFVIVESTDPATGDCIRNTVPC--------------RKQSNLT--LSSSGEPYTKLCCKGFCIDILKKLARTVKFSYDLYLVTNGKHGKL-VRGVWNGMIGEVYYRRAHLAIGSLTINEERSEIVDFSVPFVETGISVLVSRSNGTVSPSAFLEPYSPAVWMMMFVMCLSVVAVTVFIFEYFSPMGYDQDLSNGKRLGGP----SFTIGKSLWLLWALVFNNSVPIQNPRGTTSKIMVLVWAFFAVIFLASYTANLAAFMIQEQYIDTVSGLSDRKFQKPQEQYPPFRFGTVPNGSTERNIRTNYPDMHSYMVRYNQRSVEDALASLKAGKLDAFIYDAAVLNYMAGKDEGCKLVTIGSGKVFATTGYGIALQKNSRWKRPIDLALLQFLGDGDTQRLETVWLSGICQNEKNEAVSSK-LDIDNMAGVFYMLLVAMGLSLLVFSWEHLVYWRMRHCMPS--SCGEKGLLGISRG 846          
BLAST of Glutamate receptor ionotropic, NMDA 2B vs. Ensembl Xenopus
Match: GRIN2C (glutamate receptor, ionotropic, N-methyl D-aspartate 2C [Source:NCBI gene;Acc:100496638])

HSP 1 Score: 330.872 bits (847), Expect = 1.249e-94
Identity = 190/483 (39.34%), Postives = 275/483 (56.94%), Query Frame = 2
Query: 1559 LRVSTLKEEPFVIFSVKQDKT--CGNNALACSVLHDSLSISVDDFEKSKNRTKYLYMGNENYTDACCTGMAIDILRELMKDLNFEVDLYEVPDRKWGAWSAEKGWNGLLESLINRKVDMAVSAFKITPNRSEQVDFTVPFQETGIAILVALHEGSISPTAFLKPYDWASWMVILIFSVHCCSTAMFIYEWLSPKGLD-------RGNVPPREHKFSLFRALWLIWAMLFGASVNVDSPRGMASRFLGCIWALFGLVFLASYTANLAAFMIAKEDHYDLKGLNDWRFQRPWNFKPEFRFATVPFSASEENIALNYPDIALYMRRYNKSSVEEGIRALKQKEIDAFIYDSNVLEFRAAKDEGCKLRTVGN--LYAVTGYGIAFPKGSKWYSKVNDLIMQYQKYDLLHRWKTFWLTGACKKTDKLANTNRTLGVRNFISAFXXXXXXXXXXXXXXXCEHLFFRYLRPRMSNLDQYGCCGLISLSMG 2974
            L V+TL+E PFVI       T  C  N + C               K  N T  L    E YT  CC G  IDIL++L + + F  DLY V + K G       WNG++  +  R+  +A+ +  I   RSE VDF+VPF ETGI++LV+   G++SP+AFL+PY  A WM++ +  +   +  +FI+E+ SP G D       R   P     F++ ++LWL+WA++F  SV + +PRG  S+ +  +WA F ++FLASYTANLAAFMI ++    + GL+D +FQ+P    P FRF TVP  ++E NI  NYPD+  YM RYN+ SVE+ + +LK  ++DAFIYD+ VL + A KDEGCKL T+G+  ++A TGYGIA  K S+W   ++  ++Q+       R +T WL+G C+     A +++ L + N    F +LL  + +S L+   EHL   Y R R       G  GL+ +S G
Sbjct:  398 LTVATLEERPFVIVESTDPATGDCIRNTVPC--------------RKQSNLT--LSSSGEPYTKLCCKGFCIDILKKLARTVKFSYDLYLVTNGKHGKL-VRGVWNGMIGEVYYRRAHLAIGSLTINEERSEIVDFSVPFVETGISVLVSRSNGTVSPSAFLEPYSPAVWMMMFVMCLSVVAVTVFIFEYFSPMGYDQDLSNGKRLGGP----SFTIGKSLWLLWALVFNNSVPIQNPRGTTSKIMVLVWAFFAVIFLASYTANLAAFMIQEQYIDTVSGLSDRKFQKPQEQYPPFRFGTVPNGSTERNIRTNYPDMHSYMVRYNQRSVEDALASLKAGKLDAFIYDAAVLNYMAGKDEGCKLVTIGSGKVFATTGYGIALQKNSRWKRPIDLALLQFLGDGDTQRLETVWLSGICQNEKNEAVSSK-LDIDNMAGVFYMLLVAMGLSLLVFSWEHLV--YWRMRHCMPSSCGEKGLLGISRG 856          
BLAST of Glutamate receptor ionotropic, NMDA 2B vs. Ensembl Xenopus
Match: GRIN2A (glutamate receptor, ionotropic, N-methyl D-aspartate 2A [Source:NCBI gene;Acc:100489006])

HSP 1 Score: 331.643 bits (849), Expect = 2.941e-94
Identity = 206/650 (31.69%), Postives = 338/650 (52.00%), Query Frame = 2
Query: 1097 LNIATSFWKTSVEXXXXXXXXXXXXXXXEILER--MIP--KLNCQSKVDRNDAWTFGKYIYKFMSTLSVDYNSNFYQFSVHNYLNSTSFLVMNTRSILDKSPLYEMEKEKHFVTSWTKVGTWIMSSTLEEKRTKLQIDGVTWPGEVNKPPLGRPSKFKLRVSTLKEEPFVIFSVKQ--DKTCGNNALACSVLHDSLSISVDDFEKSKNRTKYLYMGNENY----TDACCTGMAIDILRELMKDLNFEVDLYEVPDRKWGAWSAEKGWNGLLESLINRKVDMAVSAFKITPNRSEQVDFTVPFQETGIAILVALHEGSISPTAFLKPYDWASWMVILIFSVHCCSTAMFIYEWLSPKGLDRG---NVPPREHKFSLFRALWLIWAMLFGASVNVDSPRGMASRFLGCIWALFGLVFLASYTANLAAFMIAKEDHYDLKGLNDWRFQRPWNFKPEFRFATVPFSASEENIALNYPDIALYMRRYNKSSVEEGIRALKQKEIDAFIYDSNVLEFRAAKDEGCKLRTVGN--LYAVTGYGIAFPKGSKWYSKVNDLIMQYQKYDLLHRWKTFWLTGACKKTDKLANTNRTLGVRNFISAFXXXXXXXXXXXXXXXCEHLFFRYLRPRMSNLDQYGCCGLISLSMGQLLSFEQTV 3001
            ++++   W  ++E  + +       + + +LE+  +IP  K +C ++ +RN+       ++KFM  ++V ++     F+   Y  +   +V+          L  M++E      W KVG W        +   L +    WP  +       P    L + TL+E PFVI         TC  N + C                     KY  + N          CC G  IDIL++L K + F  DLY V + K G    +  WNG++  ++ ++  MAV +  I   RSE VDF+VPF ETGI+++V+   G++SP+AFL+P+  + W+++ +  +   + A+F++E+ SP G +R       P    F++ +A+WL+W ++F  SV V +P+G  S+ +  IWA F ++FLASYTANLAAFMI +E    + GL+D +FQRP ++ P FRF TVP  ++E NI  NYPD+  YM ++++  V++ + +LK  ++DAFIYD+ VL + A +DEGCKL T+G+  ++A TGYGIA  KGS+W   ++  ++Q+     +   +  WLTG C  T+K    +  L + N    F +L   + +S +  + EHLF+  LR        Y   G+ + + G L S  + +
Sbjct:  137 VSVSYDDWDYNIEARVRDGLGIITTAASAMLEKHSVIPEAKTSCYAQNERNEPPLHT--LHKFM--INVTWDGKDLSFTEDGYQANPKLVVL----------LLNMDRE------WEKVGKW--------ENKSLNMKYPVWP-RITASLDSDPDDNHLSIVTLEEAPFVIVENVDYLTGTCVRNTVPCR--------------------KYFRLNNSTTEGTSVKKCCKGFCIDILKKLSKTVKFTYDLYLVTNGKHGK-KIKNVWNGMIGEVVYKRAVMAVGSLTINEERSEAVDFSVPFVETGISVMVSRSNGTVSPSAFLEPFSASVWVMMFVMLLLVSAVAVFVFEYFSPVGYNRNLADGKAPHGPSFTIGKAVWLLWGLVFNNSVPVQNPKGTTSKIIVSIWAFFAVIFLASYTANLAAFMIQEEFVDQVTGLSDKKFQRPHDYSPPFRFGTVPNGSTERNIRNNYPDMHQYMVKFHQKGVQDALVSLKTGKLDAFIYDAAVLNYMAGRDEGCKLVTIGSGYIFATTGYGIALQKGSRWKRPIDLALLQFVGDGEMEELEKLWLTGIC-HTEKNEVMSSQLDIDNMAGVFYMLAAAMALSLITFVWEHLFYWKLR--------YCFTGVCTGTPGLLFSISRGI 727          
BLAST of Glutamate receptor ionotropic, NMDA 2B vs. Ensembl Xenopus
Match: GRIN2C (glutamate receptor, ionotropic, N-methyl D-aspartate 2C [Source:NCBI gene;Acc:100496638])

HSP 1 Score: 327.405 bits (838), Expect = 1.605e-93
Identity = 186/484 (38.43%), Postives = 275/484 (56.82%), Query Frame = 2
Query: 1559 LRVSTLKEEPFVIFSVKQDKT--CGNNALACSVLHDSLSISVDDFEKSKNRTKYLYMGNENYTDACCTGMAIDILRELMKDLNFEVDLYEVPDRKWGAWSAEKGWNGLLESLINRKVDMAVSAFKITPNRSEQVDFTVPFQETGIAILVALHEGSISPTAFLKPYDWASWMVILIFSVHCCSTAMFIYEWLSPKGLD-------RGNVPPREHKFSLFRALWLIWAMLFGASVNVDSPRGMASRFLGCIWALFGLVFLASYTANLAAFMIAKEDHYDLKGLNDWRFQRPWNFKPEFRFATVPFSASEENIALNYPDIALYMRRYNKSSVEEGIRALKQKEIDAFIYDSNVLEFRAAKDEGCKLRTVGN--LYAVTGYGIAFPKGSKWYSKVNDLIMQY-QKYDLLHRWKTFWLTGACKKTDKLANTNRTLGVRNFISAFXXXXXXXXXXXXXXXCEHLFFRYLRPRMSNLDQYGCCGLISLSMG 2974
            L V+TL+E PFVI       T  C  N + C                 + ++       E YT  CC G  IDIL++L + + F  DLY V + K G       WNG++  +  R+  +A+ +  I   RSE VDF+VPF ETGI++LV+   G++SP+AFL+PY  A WM++ +  +   +  +FI+E+ SP G D       R   P     F++ ++LWL+WA++F  SV + +PRG  S+ +  +WA F ++FLASYTANLAAFMI ++    + GL+D +FQ+P    P FRF TVP  ++E NI  NYPD+  YM RYN+ SVE+ + +LK  ++DAFIYD+ VL + A KDEGCKL T+G+  ++A TGYGIA  K S+W   ++  ++Q+    +   R +T WL+G C+     A +++ L + N    F +LL  + +S L+   EHL   Y R R       G  GL+ +S G
Sbjct:  387 LTVATLEERPFVIVESTDPATGDCIRNTVPC-----------------RKQSNLTLSSGEPYTKLCCKGFCIDILKKLARTVKFSYDLYLVTNGKHGKL-VRGVWNGMIGEVYYRRAHLAIGSLTINEERSEIVDFSVPFVETGISVLVSRSNGTVSPSAFLEPYSPAVWMMMFVMCLSVVAVTVFIFEYFSPMGYDQDLSNGKRLGGP----SFTIGKSLWLLWALVFNNSVPIQNPRGTTSKIMVLVWAFFAVIFLASYTANLAAFMIQEQYIDTVSGLSDRKFQKPQEQYPPFRFGTVPNGSTERNIRTNYPDMHSYMVRYNQRSVEDALASLKAGKLDAFIYDAAVLNYMAGKDEGCKLVTIGSGKVFATTGYGIALQKNSRWKRPIDLALLQFLGDGEYTQRLETVWLSGICQNEKNEAVSSK-LDIDNMAGVFYMLLVAMGLSLLVFSWEHLV--YWRMRHCMPSSCGEKGLLGISRG 845          
BLAST of Glutamate receptor ionotropic, NMDA 2B vs. Ensembl Mouse
Match: Grin2a (glutamate receptor, ionotropic, NMDA2A (epsilon 1) [Source:MGI Symbol;Acc:MGI:95820])

HSP 1 Score: 327.02 bits (837), Expect = 2.316e-92
Identity = 186/503 (36.98%), Postives = 281/503 (55.86%), Query Frame = 2
Query: 1430 WTKVGTWIMSSTLEEKRTKLQIDGVTWPGEVNKPPLGRPSKFKLRVSTLKEEPFVIFSVKQ--DKTCGNNALACSVLHDSLSISVDDFEKSKNRTKYLYMGNENY-TDACCTGMAIDILRELMKDLNFEVDLYEVPDRKWGAWSAEKGWNGLLESLINRKVDMAVSAFKITPNRSEQVDFTVPFQETGIAILVALHEGSISPTAFLKPYDWASWMVILIFSVHCCSTAMFIYEWLSPKGLDRG---NVPPREHKFSLFRALWLIWAMLFGASVNVDSPRGMASRFLGCIWALFGLVFLASYTANLAAFMIAKEDHYDLKGLNDWRFQRPWNFKPEFRFATVPFSASEENIALNYPDIALYMRRYNKSSVEEGIRALKQKEIDAFIYDSNVLEFRAAKDEGCKLRTVGN--LYAVTGYGIAFPKGSKWYSKVNDLIMQYQKYDLLHRWKTFWLTGACKKTDKLANTNRTLGVRNFISAFXXXXXXXXXXXXXXXCEHLFFRYLR 2914
            W KVG W       E +T L +    WP          P    L + TL+E PFVI        +TC  N + C             F K  N T      NE      CC G  IDIL++L + + F  DLY V + K G       WNG++  ++ ++  MAV +  I   RSE VDF+VPF ETGI+++V+   G++SP+AFL+P+  + W+++ +  +   + A+F++E+ SP G +R       P    F++ +A+WL+W ++F  SV V +P+G  S+ +  +WA F ++FLASYTANLAAFMI +E    + GL+D +FQRP ++ P FRF TVP  ++E NI  NYP +  YM ++N+  VE+ + +LK  ++DAFIYD+ VL ++A +DEGCKL T+G+  ++A TGYGIA  KGS W  +++  ++Q+     +   +T WLTG C   +K    +  L + N    F +L   + +S +  I EHLF+  LR
Sbjct:  372 WEKVGKW-------ENQT-LSLRHAVWP-RYKSFSDCEPDDNHLSIVTLEEAPFVIVEDIDPLTETCVRNTVPCR-----------KFVKINNST------NEGMNVKKCCKGFCIDILKKLSRTVKFTYDLYLVTNGKHGK-KVNNVWNGMIGEVVYQRAVMAVGSLTINEERSEVVDFSVPFVETGISVMVSRSNGTVSPSAFLEPFSASVWVMMFVMLLIVSAIAVFVFEYFSPVGYNRNLAKGKAPHGPSFTIGKAIWLLWGLVFNNSVPVQNPKGTTSKIMVSVWAFFAVIFLASYTANLAAFMIQEEFVDQVTGLSDKKFQRPHDYSPPFRFGTVPNGSTERNIRNNYPYMHQYMTKFNQRGVEDALVSLKTGKLDAFIYDAAVLNYKAGRDEGCKLVTIGSGYIFATTGYGIALQKGSPWKRQIDLALLQFVGDGEMEELETLWLTGIC-HNEKNEVMSSQLDIDNMAGVFYMLAAAMALSLITFIWEHLFYWKLR 846          
BLAST of Glutamate receptor ionotropic, NMDA 2B vs. Ensembl Mouse
Match: Grin2a (glutamate receptor, ionotropic, NMDA2A (epsilon 1) [Source:MGI Symbol;Acc:MGI:95820])

HSP 1 Score: 327.02 bits (837), Expect = 2.316e-92
Identity = 186/503 (36.98%), Postives = 281/503 (55.86%), Query Frame = 2
Query: 1430 WTKVGTWIMSSTLEEKRTKLQIDGVTWPGEVNKPPLGRPSKFKLRVSTLKEEPFVIFSVKQ--DKTCGNNALACSVLHDSLSISVDDFEKSKNRTKYLYMGNENY-TDACCTGMAIDILRELMKDLNFEVDLYEVPDRKWGAWSAEKGWNGLLESLINRKVDMAVSAFKITPNRSEQVDFTVPFQETGIAILVALHEGSISPTAFLKPYDWASWMVILIFSVHCCSTAMFIYEWLSPKGLDRG---NVPPREHKFSLFRALWLIWAMLFGASVNVDSPRGMASRFLGCIWALFGLVFLASYTANLAAFMIAKEDHYDLKGLNDWRFQRPWNFKPEFRFATVPFSASEENIALNYPDIALYMRRYNKSSVEEGIRALKQKEIDAFIYDSNVLEFRAAKDEGCKLRTVGN--LYAVTGYGIAFPKGSKWYSKVNDLIMQYQKYDLLHRWKTFWLTGACKKTDKLANTNRTLGVRNFISAFXXXXXXXXXXXXXXXCEHLFFRYLR 2914
            W KVG W       E +T L +    WP          P    L + TL+E PFVI        +TC  N + C             F K  N T      NE      CC G  IDIL++L + + F  DLY V + K G       WNG++  ++ ++  MAV +  I   RSE VDF+VPF ETGI+++V+   G++SP+AFL+P+  + W+++ +  +   + A+F++E+ SP G +R       P    F++ +A+WL+W ++F  SV V +P+G  S+ +  +WA F ++FLASYTANLAAFMI +E    + GL+D +FQRP ++ P FRF TVP  ++E NI  NYP +  YM ++N+  VE+ + +LK  ++DAFIYD+ VL ++A +DEGCKL T+G+  ++A TGYGIA  KGS W  +++  ++Q+     +   +T WLTG C   +K    +  L + N    F +L   + +S +  I EHLF+  LR
Sbjct:  372 WEKVGKW-------ENQT-LSLRHAVWP-RYKSFSDCEPDDNHLSIVTLEEAPFVIVEDIDPLTETCVRNTVPCR-----------KFVKINNST------NEGMNVKKCCKGFCIDILKKLSRTVKFTYDLYLVTNGKHGK-KVNNVWNGMIGEVVYQRAVMAVGSLTINEERSEVVDFSVPFVETGISVMVSRSNGTVSPSAFLEPFSASVWVMMFVMLLIVSAIAVFVFEYFSPVGYNRNLAKGKAPHGPSFTIGKAIWLLWGLVFNNSVPVQNPKGTTSKIMVSVWAFFAVIFLASYTANLAAFMIQEEFVDQVTGLSDKKFQRPHDYSPPFRFGTVPNGSTERNIRNNYPYMHQYMTKFNQRGVEDALVSLKTGKLDAFIYDAAVLNYKAGRDEGCKLVTIGSGYIFATTGYGIALQKGSPWKRQIDLALLQFVGDGEMEELETLWLTGIC-HNEKNEVMSSQLDIDNMAGVFYMLAAAMALSLITFIWEHLFYWKLR 846          
BLAST of Glutamate receptor ionotropic, NMDA 2B vs. Ensembl Mouse
Match: Grin2a (glutamate receptor, ionotropic, NMDA2A (epsilon 1) [Source:MGI Symbol;Acc:MGI:95820])

HSP 1 Score: 327.02 bits (837), Expect = 2.316e-92
Identity = 186/503 (36.98%), Postives = 281/503 (55.86%), Query Frame = 2
Query: 1430 WTKVGTWIMSSTLEEKRTKLQIDGVTWPGEVNKPPLGRPSKFKLRVSTLKEEPFVIFSVKQ--DKTCGNNALACSVLHDSLSISVDDFEKSKNRTKYLYMGNENY-TDACCTGMAIDILRELMKDLNFEVDLYEVPDRKWGAWSAEKGWNGLLESLINRKVDMAVSAFKITPNRSEQVDFTVPFQETGIAILVALHEGSISPTAFLKPYDWASWMVILIFSVHCCSTAMFIYEWLSPKGLDRG---NVPPREHKFSLFRALWLIWAMLFGASVNVDSPRGMASRFLGCIWALFGLVFLASYTANLAAFMIAKEDHYDLKGLNDWRFQRPWNFKPEFRFATVPFSASEENIALNYPDIALYMRRYNKSSVEEGIRALKQKEIDAFIYDSNVLEFRAAKDEGCKLRTVGN--LYAVTGYGIAFPKGSKWYSKVNDLIMQYQKYDLLHRWKTFWLTGACKKTDKLANTNRTLGVRNFISAFXXXXXXXXXXXXXXXCEHLFFRYLR 2914
            W KVG W       E +T L +    WP          P    L + TL+E PFVI        +TC  N + C             F K  N T      NE      CC G  IDIL++L + + F  DLY V + K G       WNG++  ++ ++  MAV +  I   RSE VDF+VPF ETGI+++V+   G++SP+AFL+P+  + W+++ +  +   + A+F++E+ SP G +R       P    F++ +A+WL+W ++F  SV V +P+G  S+ +  +WA F ++FLASYTANLAAFMI +E    + GL+D +FQRP ++ P FRF TVP  ++E NI  NYP +  YM ++N+  VE+ + +LK  ++DAFIYD+ VL ++A +DEGCKL T+G+  ++A TGYGIA  KGS W  +++  ++Q+     +   +T WLTG C   +K    +  L + N    F +L   + +S +  I EHLF+  LR
Sbjct:  372 WEKVGKW-------ENQT-LSLRHAVWP-RYKSFSDCEPDDNHLSIVTLEEAPFVIVEDIDPLTETCVRNTVPCR-----------KFVKINNST------NEGMNVKKCCKGFCIDILKKLSRTVKFTYDLYLVTNGKHGK-KVNNVWNGMIGEVVYQRAVMAVGSLTINEERSEVVDFSVPFVETGISVMVSRSNGTVSPSAFLEPFSASVWVMMFVMLLIVSAIAVFVFEYFSPVGYNRNLAKGKAPHGPSFTIGKAIWLLWGLVFNNSVPVQNPKGTTSKIMVSVWAFFAVIFLASYTANLAAFMIQEEFVDQVTGLSDKKFQRPHDYSPPFRFGTVPNGSTERNIRNNYPYMHQYMTKFNQRGVEDALVSLKTGKLDAFIYDAAVLNYKAGRDEGCKLVTIGSGYIFATTGYGIALQKGSPWKRQIDLALLQFVGDGEMEELETLWLTGIC-HNEKNEVMSSQLDIDNMAGVFYMLAAAMALSLITFIWEHLFYWKLR 846          
BLAST of Glutamate receptor ionotropic, NMDA 2B vs. Ensembl Mouse
Match: Grin2d (glutamate receptor, ionotropic, NMDA2D (epsilon 4) [Source:MGI Symbol;Acc:MGI:95823])

HSP 1 Score: 323.168 bits (827), Expect = 1.843e-91
Identity = 188/505 (37.23%), Postives = 285/505 (56.44%), Query Frame = 2
Query: 1421 VTSWTKVGTWIMSSTLEEKRTKLQIDGVTWPGEVNKPPLGRPSKFKLRVSTLKEEPFVIFSVKQ--DKTCGNNALACSVLHDSLSISVDDFEKSKNRTKYLYMGNENYTDACCTGMAIDILRELMKDLNFEVDLYEVPDRKWGAWSAEKGWNGLLESLINRKVDMAVSAFKITPNRSEQVDFTVPFQETGIAILVALHEGSISPTAFLKPYDWASWMVILIFSVHCCSTAMFIYEWLSPKGLDRG---NVPPREHKFSLFRALWLIWAMLFGASVNVDSPRGMASRFLGCIWALFGLVFLASYTANLAAFMIAKEDHYDLKGLNDWRFQRPWNFKPEFRFATVPFSASEENIALNYPDIALYMRRYNKSSVEEGIRALKQKEIDAFIYDSNVLEFRAAKDEGCKLRTVGN--LYAVTGYGIAFPKGSKWYSKVNDLIMQYQKYDLLHRWKTFWLTGACKKTDKLANTNRTLGVRNFISAFXXXXXXXXXXXXXXXCEHLFFRYLR 2914
            V S T+  TW +  + E++  +L+    +  G   +P         L V+TL+E PFVI         TC  +++ C    +       D  + + R              CC G  IDIL+ L   + F  DLY V + K G    +  WNG++  +  ++ DMA+ +  I   RSE VDF+VPF ETGI+++VA   G++SP+AFL+PY  A W+++ +  +   +  +FI+E+LSP G +R       P    F++ +++WL+WA++F  SV V++PRG  S+ +  +WA F ++FLASYTANLAAFMI +E    + GL+D +FQRP    P  +F TVP  ++E+NI  NYPD+  YM RYN+  VEE +  LK  ++DAFIYD+ VL + A KDEGCKL T+G+  ++A TGYGIA  KGS+W   ++  ++Q+   D +   +  WL+G C   DK+   +  L + N    F +LL  + +S L+   EHL +  LR
Sbjct:  386 VISLTRDRTWEVVGSWEQQTLRLKYPLWSRYGRFLQP---VDDTQHLTVATLEERPFVIVEPADPISGTCIRDSVPCRSQLNRTHSPPPDAPRPEKR--------------CCKGFCIDILKRLAHTIGFSYDLYLVTNGKHGK-KIDGVWNGMIGEVFYQRADMAIGSLTINEERSEIVDFSVPFVETGISVMVARSNGTVSPSAFLEPYSPAVWVMMFVMCLTVVAVTVFIFEYLSPVGYNRSLATGKRPGGSTFTIGKSIWLLWALVFNNSVPVENPRGTTSKIMVLVWAFFAVIFLASYTANLAAFMIQEEYVDTVSGLSDRKFQRPQEQYPPLKFGTVPNGSTEKNIRSNYPDMHSYMVRYNQPRVEEALTQLKAGKLDAFIYDAAVLNYMARKDEGCKLVTIGSGKVFATTGYGIALHKGSRWKRPIDLALLQFLGDDEIEMLERLWLSGICHN-DKIEVMSSKLDIDNMAGVFYMLLVAMGLSLLVFAWEHLVYWRLR 871          
BLAST of Glutamate receptor ionotropic, NMDA 2B vs. Ensembl Mouse
Match: Grin2d (glutamate receptor, ionotropic, NMDA2D (epsilon 4) [Source:MGI Symbol;Acc:MGI:95823])

HSP 1 Score: 323.168 bits (827), Expect = 1.843e-91
Identity = 188/505 (37.23%), Postives = 285/505 (56.44%), Query Frame = 2
Query: 1421 VTSWTKVGTWIMSSTLEEKRTKLQIDGVTWPGEVNKPPLGRPSKFKLRVSTLKEEPFVIFSVKQ--DKTCGNNALACSVLHDSLSISVDDFEKSKNRTKYLYMGNENYTDACCTGMAIDILRELMKDLNFEVDLYEVPDRKWGAWSAEKGWNGLLESLINRKVDMAVSAFKITPNRSEQVDFTVPFQETGIAILVALHEGSISPTAFLKPYDWASWMVILIFSVHCCSTAMFIYEWLSPKGLDRG---NVPPREHKFSLFRALWLIWAMLFGASVNVDSPRGMASRFLGCIWALFGLVFLASYTANLAAFMIAKEDHYDLKGLNDWRFQRPWNFKPEFRFATVPFSASEENIALNYPDIALYMRRYNKSSVEEGIRALKQKEIDAFIYDSNVLEFRAAKDEGCKLRTVGN--LYAVTGYGIAFPKGSKWYSKVNDLIMQYQKYDLLHRWKTFWLTGACKKTDKLANTNRTLGVRNFISAFXXXXXXXXXXXXXXXCEHLFFRYLR 2914
            V S T+  TW +  + E++  +L+    +  G   +P         L V+TL+E PFVI         TC  +++ C    +       D  + + R              CC G  IDIL+ L   + F  DLY V + K G    +  WNG++  +  ++ DMA+ +  I   RSE VDF+VPF ETGI+++VA   G++SP+AFL+PY  A W+++ +  +   +  +FI+E+LSP G +R       P    F++ +++WL+WA++F  SV V++PRG  S+ +  +WA F ++FLASYTANLAAFMI +E    + GL+D +FQRP    P  +F TVP  ++E+NI  NYPD+  YM RYN+  VEE +  LK  ++DAFIYD+ VL + A KDEGCKL T+G+  ++A TGYGIA  KGS+W   ++  ++Q+   D +   +  WL+G C   DK+   +  L + N    F +LL  + +S L+   EHL +  LR
Sbjct:  386 VISLTRDRTWEVVGSWEQQTLRLKYPLWSRYGRFLQP---VDDTQHLTVATLEERPFVIVEPADPISGTCIRDSVPCRSQLNRTHSPPPDAPRPEKR--------------CCKGFCIDILKRLAHTIGFSYDLYLVTNGKHGK-KIDGVWNGMIGEVFYQRADMAIGSLTINEERSEIVDFSVPFVETGISVMVARSNGTVSPSAFLEPYSPAVWVMMFVMCLTVVAVTVFIFEYLSPVGYNRSLATGKRPGGSTFTIGKSIWLLWALVFNNSVPVENPRGTTSKIMVLVWAFFAVIFLASYTANLAAFMIQEEYVDTVSGLSDRKFQRPQEQYPPLKFGTVPNGSTEKNIRSNYPDMHSYMVRYNQPRVEEALTQLKAGKLDAFIYDAAVLNYMARKDEGCKLVTIGSGKVFATTGYGIALHKGSRWKRPIDLALLQFLGDDEIEMLERLWLSGICHN-DKIEVMSSKLDIDNMAGVFYMLLVAMGLSLLVFAWEHLVYWRLR 871          
BLAST of Glutamate receptor ionotropic, NMDA 2B vs. UniProt/SwissProt
Match: sp|Q00959|NMDE1_RAT (Glutamate receptor ionotropic, NMDA 2A OS=Rattus norvegicus OX=10116 GN=Grin2a PE=1 SV=2)

HSP 1 Score: 327.405 bits (838), Expect = 1.200e-91
Identity = 187/503 (37.18%), Postives = 281/503 (55.86%), Query Frame = 2
Query: 1430 WTKVGTWIMSSTLEEKRTKLQIDGVTWPGEVNKPPLGRPSKFKLRVSTLKEEPFVIFSVKQ--DKTCGNNALACSVLHDSLSISVDDFEKSKNRTKYLYMGNENY-TDACCTGMAIDILRELMKDLNFEVDLYEVPDRKWGAWSAEKGWNGLLESLINRKVDMAVSAFKITPNRSEQVDFTVPFQETGIAILVALHEGSISPTAFLKPYDWASWMVILIFSVHCCSTAMFIYEWLSPKGLDRG---NVPPREHKFSLFRALWLIWAMLFGASVNVDSPRGMASRFLGCIWALFGLVFLASYTANLAAFMIAKEDHYDLKGLNDWRFQRPWNFKPEFRFATVPFSASEENIALNYPDIALYMRRYNKSSVEEGIRALKQKEIDAFIYDSNVLEFRAAKDEGCKLRTVGN--LYAVTGYGIAFPKGSKWYSKVNDLIMQYQKYDLLHRWKTFWLTGACKKTDKLANTNRTLGVRNFISAFXXXXXXXXXXXXXXXCEHLFFRYLR 2914
            W KVG W       E +T L +    WP          P    L + TL+E PFVI        +TC  N + C             F K  N T      NE      CC G  IDIL++L + + F  DLY V + K G       WNG++  ++ ++  MAV +  I   RSE VDF+VPF ETGI+++V+   G++SP+AFL+P+  + W+++ +  +   + A+F++E+ SP G +R       P    F++ +A+WL+W ++F  SV V +P+G  S+ +  +WA F ++FLASYTANLAAFMI +E    + GL+D +FQRP ++ P FRF TVP  ++E NI  NYP +  YM R+N+  VE+ + +LK  ++DAFIYD+ VL ++A +DEGCKL T+G+  ++A TGYGIA  KGS W  +++  ++Q+     +   +T WLTG C   +K    +  L + N    F +L   + +S +  I EHLF+  LR
Sbjct:  372 WEKVGKW-------ENQT-LSLRHAVWP-RYKSFSDCEPDDNHLSIVTLEEAPFVIVEDIDPLTETCVRNTVPCR-----------KFVKINNST------NEGMNVKKCCKGFCIDILKKLSRTVKFTYDLYLVTNGKHGK-KVNNVWNGMIGEVVYQRAVMAVGSLTINEERSEVVDFSVPFVETGISVMVSRSNGTVSPSAFLEPFSASVWVMMFVMLLIVSAIAVFVFEYFSPVGYNRNLAKGKAPHGPSFTIGKAIWLLWGLVFNNSVPVQNPKGTTSKIMVSVWAFFAVIFLASYTANLAAFMIQEEFVDQVTGLSDKKFQRPHDYSPPFRFGTVPNGSTERNIRNNYPYMHQYMTRFNQRGVEDALVSLKTGKLDAFIYDAAVLNYKAGRDEGCKLVTIGSGYIFASTGYGIALQKGSPWKRQIDLALLQFVGDGEMEELETLWLTGIC-HNEKNEVMSSQLDIDNMAGVFYMLAAAMALSLITFIWEHLFYWKLR 846          
BLAST of Glutamate receptor ionotropic, NMDA 2B vs. UniProt/SwissProt
Match: sp|P35436|NMDE1_MOUSE (Glutamate receptor ionotropic, NMDA 2A OS=Mus musculus OX=10090 GN=Grin2a PE=1 SV=2)

HSP 1 Score: 327.02 bits (837), Expect = 1.620e-91
Identity = 186/503 (36.98%), Postives = 281/503 (55.86%), Query Frame = 2
Query: 1430 WTKVGTWIMSSTLEEKRTKLQIDGVTWPGEVNKPPLGRPSKFKLRVSTLKEEPFVIFSVKQ--DKTCGNNALACSVLHDSLSISVDDFEKSKNRTKYLYMGNENY-TDACCTGMAIDILRELMKDLNFEVDLYEVPDRKWGAWSAEKGWNGLLESLINRKVDMAVSAFKITPNRSEQVDFTVPFQETGIAILVALHEGSISPTAFLKPYDWASWMVILIFSVHCCSTAMFIYEWLSPKGLDRG---NVPPREHKFSLFRALWLIWAMLFGASVNVDSPRGMASRFLGCIWALFGLVFLASYTANLAAFMIAKEDHYDLKGLNDWRFQRPWNFKPEFRFATVPFSASEENIALNYPDIALYMRRYNKSSVEEGIRALKQKEIDAFIYDSNVLEFRAAKDEGCKLRTVGN--LYAVTGYGIAFPKGSKWYSKVNDLIMQYQKYDLLHRWKTFWLTGACKKTDKLANTNRTLGVRNFISAFXXXXXXXXXXXXXXXCEHLFFRYLR 2914
            W KVG W       E +T L +    WP          P    L + TL+E PFVI        +TC  N + C             F K  N T      NE      CC G  IDIL++L + + F  DLY V + K G       WNG++  ++ ++  MAV +  I   RSE VDF+VPF ETGI+++V+   G++SP+AFL+P+  + W+++ +  +   + A+F++E+ SP G +R       P    F++ +A+WL+W ++F  SV V +P+G  S+ +  +WA F ++FLASYTANLAAFMI +E    + GL+D +FQRP ++ P FRF TVP  ++E NI  NYP +  YM ++N+  VE+ + +LK  ++DAFIYD+ VL ++A +DEGCKL T+G+  ++A TGYGIA  KGS W  +++  ++Q+     +   +T WLTG C   +K    +  L + N    F +L   + +S +  I EHLF+  LR
Sbjct:  372 WEKVGKW-------ENQT-LSLRHAVWP-RYKSFSDCEPDDNHLSIVTLEEAPFVIVEDIDPLTETCVRNTVPCR-----------KFVKINNST------NEGMNVKKCCKGFCIDILKKLSRTVKFTYDLYLVTNGKHGK-KVNNVWNGMIGEVVYQRAVMAVGSLTINEERSEVVDFSVPFVETGISVMVSRSNGTVSPSAFLEPFSASVWVMMFVMLLIVSAIAVFVFEYFSPVGYNRNLAKGKAPHGPSFTIGKAIWLLWGLVFNNSVPVQNPKGTTSKIMVSVWAFFAVIFLASYTANLAAFMIQEEFVDQVTGLSDKKFQRPHDYSPPFRFGTVPNGSTERNIRNNYPYMHQYMTKFNQRGVEDALVSLKTGKLDAFIYDAAVLNYKAGRDEGCKLVTIGSGYIFATTGYGIALQKGSPWKRQIDLALLQFVGDGEMEELETLWLTGIC-HNEKNEVMSSQLDIDNMAGVFYMLAAAMALSLITFIWEHLFYWKLR 846          
BLAST of Glutamate receptor ionotropic, NMDA 2B vs. UniProt/SwissProt
Match: sp|Q5IS45|NMDE1_PANTR (Glutamate receptor ionotropic, NMDA 2A OS=Pan troglodytes OX=9598 GN=GRIN2A PE=2 SV=1)

HSP 1 Score: 326.25 bits (835), Expect = 2.950e-91
Identity = 186/503 (36.98%), Postives = 280/503 (55.67%), Query Frame = 2
Query: 1430 WTKVGTWIMSSTLEEKRTKLQIDGVTWPGEVNKPPLGRPSKFKLRVSTLKEEPFVIFSVKQ--DKTCGNNALACSVLHDSLSISVDDFEKSKNRTKYLYMGNENY-TDACCTGMAIDILRELMKDLNFEVDLYEVPDRKWGAWSAEKGWNGLLESLINRKVDMAVSAFKITPNRSEQVDFTVPFQETGIAILVALHEGSISPTAFLKPYDWASWMVILIFSVHCCSTAMFIYEWLSPKGLDRG---NVPPREHKFSLFRALWLIWAMLFGASVNVDSPRGMASRFLGCIWALFGLVFLASYTANLAAFMIAKEDHYDLKGLNDWRFQRPWNFKPEFRFATVPFSASEENIALNYPDIALYMRRYNKSSVEEGIRALKQKEIDAFIYDSNVLEFRAAKDEGCKLRTVGN--LYAVTGYGIAFPKGSKWYSKVNDLIMQYQKYDLLHRWKTFWLTGACKKTDKLANTNRTLGVRNFISAFXXXXXXXXXXXXXXXCEHLFFRYLR 2914
            W KVG W       E  T L +    WP          P    L + TL+E PFVI        +TC  N + C             F K  N T      NE      CC G  IDIL++L + + F  DLY V + K G       WNG++  ++ ++  MAV +  I   RSE VDF+VPF ETGI+++V+   G++SP+AFL+P+  + W+++ +  +   + A+F++E+ SP G +R       P    F++ +A+WL+W ++F  SV V +P+G  S+ +  +WA F ++FLASYTANLAAFMI +E    + GL+D +FQRP ++ P FRF TVP  ++E NI  NYP +  YM ++N+  VE+ + +LK  ++DAFIYD+ VL ++A +DEGCKL T+G+  ++A TGYGIA  KGS W  +++  ++Q+     +   +T WLTG C   +K    +  L + N    F +L   + +S +  I EHLF+  LR
Sbjct:  372 WEKVGKW-------ENHT-LSLRHAVWP-RYKSFSDCEPDDNHLSIVTLEEAPFVIVEDIDPLTETCVRNTVPCR-----------KFVKINNST------NEGMNVKKCCKGFCIDILKKLSRTVKFTYDLYLVTNGKHGK-KVNNVWNGMIGEVVYQRAVMAVGSLTINEERSEVVDFSVPFVETGISVMVSRSNGTVSPSAFLEPFSASVWVMMFVMLLIVSAIAVFVFEYFSPVGYNRNLAKGKAPHGPSFTIGKAIWLLWGLVFNNSVPVQNPKGTTSKIMVSVWAFFAVIFLASYTANLAAFMIQEEFVDQVTGLSDKKFQRPHDYSPPFRFGTVPNGSTERNIRNNYPYMHQYMTKFNQKGVEDALVSLKTGKLDAFIYDAAVLNYKAGRDEGCKLVTIGSGYIFATTGYGIALQKGSPWKRQIDLALLQFVGDGEMEELETLWLTGIC-HNEKNEVMSSQLDIDNMAGVFYMLAAAMALSLITFIWEHLFYWKLR 846          
BLAST of Glutamate receptor ionotropic, NMDA 2B vs. UniProt/SwissProt
Match: sp|Q12879|NMDE1_HUMAN (Glutamate receptor ionotropic, NMDA 2A OS=Homo sapiens OX=9606 GN=GRIN2A PE=1 SV=1)

HSP 1 Score: 325.865 bits (834), Expect = 3.834e-91
Identity = 186/503 (36.98%), Postives = 280/503 (55.67%), Query Frame = 2
Query: 1430 WTKVGTWIMSSTLEEKRTKLQIDGVTWPGEVNKPPLGRPSKFKLRVSTLKEEPFVIFSVKQ--DKTCGNNALACSVLHDSLSISVDDFEKSKNRTKYLYMGNENY-TDACCTGMAIDILRELMKDLNFEVDLYEVPDRKWGAWSAEKGWNGLLESLINRKVDMAVSAFKITPNRSEQVDFTVPFQETGIAILVALHEGSISPTAFLKPYDWASWMVILIFSVHCCSTAMFIYEWLSPKGLDRG---NVPPREHKFSLFRALWLIWAMLFGASVNVDSPRGMASRFLGCIWALFGLVFLASYTANLAAFMIAKEDHYDLKGLNDWRFQRPWNFKPEFRFATVPFSASEENIALNYPDIALYMRRYNKSSVEEGIRALKQKEIDAFIYDSNVLEFRAAKDEGCKLRTVGN--LYAVTGYGIAFPKGSKWYSKVNDLIMQYQKYDLLHRWKTFWLTGACKKTDKLANTNRTLGVRNFISAFXXXXXXXXXXXXXXXCEHLFFRYLR 2914
            W KVG W       E  T L +    WP          P    L + TL+E PFVI        +TC  N + C             F K  N T      NE      CC G  IDIL++L + + F  DLY V + K G       WNG++  ++ ++  MAV +  I   RSE VDF+VPF ETGI+++V+   G++SP+AFL+P+  + W+++ +  +   + A+F++E+ SP G +R       P    F++ +A+WL+W ++F  SV V +P+G  S+ +  +WA F ++FLASYTANLAAFMI +E    + GL+D +FQRP ++ P FRF TVP  ++E NI  NYP +  YM ++N+  VE+ + +LK  ++DAFIYD+ VL ++A +DEGCKL T+G+  ++A TGYGIA  KGS W  +++  ++Q+     +   +T WLTG C   +K    +  L + N    F +L   + +S +  I EHLF+  LR
Sbjct:  372 WEKVGKW-------ENHT-LSLRHAVWP-RYKSFSDCEPDDNHLSIVTLEEAPFVIVEDIDPLTETCVRNTVPCR-----------KFVKINNST------NEGMNVKKCCKGFCIDILKKLSRTVKFTYDLYLVTNGKHGK-KVNNVWNGMIGEVVYQRAVMAVGSLTINEERSEVVDFSVPFVETGISVMVSRSNGTVSPSAFLEPFSASVWVMMFVMLLIVSAIAVFVFEYFSPVGYNRNLAKGKAPHGPSFTIGKAIWLLWGLVFNNSVPVQNPKGTTSKIMVSVWAFFAVIFLASYTANLAAFMIQEEFVDQVTGLSDKKFQRPHDYSPPFRFGTVPNGSTERNIRNNYPYMHQYMTKFNQKGVEDALVSLKTGKLDAFIYDAAVLNYKAGRDEGCKLVTIGSGYIFATTGYGIALQKGSPWKRQIDLALLQFVGDGEMEELETLWLTGIC-HNEKNEVMSSQLDIDNMAGVFYMLAAAMALSLITFIWEHLFYWKLR 846          
BLAST of Glutamate receptor ionotropic, NMDA 2B vs. UniProt/SwissProt
Match: sp|B7ZSK1|NMDE1_XENLA (Glutamate receptor ionotropic, NMDA 2A OS=Xenopus laevis OX=8355 GN=grin2a PE=1 SV=1)

HSP 1 Score: 325.094 bits (832), Expect = 6.960e-91
Identity = 201/614 (32.74%), Postives = 319/614 (51.95%), Query Frame = 2
Query: 1118 WKTSVEXXXXXXXXXXXXXXXEILER--MIP--KLNCQSKVDRNDAWTFGKYIYKFMSTLSVDYNSNFYQFSVHNYLNSTSFLVMNTRSILDKSPLYEMEKEKHFVTSWTKVGTWIMSSTLEEKRTKLQIDGVTWPGEVNKPPLGRPSKFKLRVSTLKEEPFVIFSVKQ--DKTCGNNALACSVLHDSLSISVDDFEKSKNRTKYLYMGNENYTDA----CCTGMAIDILRELMKDLNFEVDLYEVPDRKWGAWSAEKGWNGLLESLINRKVDMAVSAFKITPNRSEQVDFTVPFQETGIAILVALHEGSISPTAFLKPYDWASWMVILIFSVHCCSTAMFIYEWLSPKGLDRG---NVPPREHKFSLFRALWLIWAMLFGASVNVDSPRGMASRFLGCIWALFGLVFLASYTANLAAFMIAKEDHYDLKGLNDWRFQRPWNFKPEFRFATVPFSASEENIALNYPDIALYMRRYNKSSVEEGIRALKQKEIDAFIYDSNVLEFRAAKDEGCKLRTVGN--LYAVTGYGIAFPKGSKWYSKVNDLIMQYQKYDLLHRWKTFWLTGACKKTDKLANTNRTLGVRNFISAFXXXXXXXXXXXXXXXCEHLFFRYLR 2914
            W   +E  + +       + + +LE+  +IP  K +C  + +RND       ++ FM  ++V ++     F+   Y  +   +V+          L  ME+E      W KVG W        +   L +    WP  +            L + TL+E PFVI         TC  N + C                     KY  + N          CC G  IDIL++L K + F  DLY V + K G    +  WNG++  ++ ++  MAV +  I   RS  VDF+VPF ETGI+++V+   G++SP+AFL+P+  + W+++ +  +   + A+FI+E+ SP G +R       P    F++ +A+WL+W ++F  SV V +P+G  S+ +  IWA F ++FLASYTANLAAFMI +E    + GL+D +FQRP ++ P FRF TVP  ++E NI  NYPD+  YM ++++  V++ + +LK  ++DAFIYD+ VL + A +DEGCKL T+G+  ++A TGYGIA  KGS+W   ++  ++Q+     +   +  WLTG C  T+K    +  L + N    F +L   + +S +  + EHLF+  LR
Sbjct:  276 WDYGIEARVRDGLGIITTAASAMLEKHSVIPEAKTSCYGQNERNDPPLHT--LHNFM--INVTWDGKDLSFTEDGYQANPKLVVL----------LLNMERE------WEKVGKW--------ENKSLNMKYPVWP-RITASLDSDHDDNHLSIVTLEEAPFVIVENIDYLTGTCVRNTVPCR--------------------KYFRLNNSTTEGTSVKKCCKGFCIDILKKLSKTVKFTYDLYLVTNGKHGK-KIKNVWNGMIGEVVYKRAVMAVGSLTINEERSVAVDFSVPFVETGISVMVSRSNGTVSPSAFLEPFSASVWVMMFVMLLLVSAMAVFIFEYFSPVGYNRNLAQGKDPHGPSFTIGKAVWLLWGLVFNNSVPVQNPKGTTSKIIVSIWAFFAVIFLASYTANLAAFMIQEEFVDQVTGLSDNKFQRPHDYSPPFRFGTVPNGSTERNIRNNYPDMHQYMVKFHQKGVQDALVSLKTGKLDAFIYDAAVLNYMAGRDEGCKLVTIGSGYIFATTGYGIALQKGSRWKRPIDLALLQFVGDGEMEELEKLWLTGIC-HTEKNEVMSSQLDIDNMAGVFYMLAAAMALSLITFVWEHLFYWKLR 838          
BLAST of Glutamate receptor ionotropic, NMDA 2B vs. TrEMBL
Match: A0A267FAS3 (Uncharacterized protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig031588g1 PE=3 SV=1)

HSP 1 Score: 796.579 bits (2056), Expect = 0.000e+0
Identity = 398/804 (49.50%), Postives = 546/804 (67.91%), Query Frame = 2
Query:  734 FDGFIDQSEIMSVLKSEERLSSYKKSLEHILAADHRIILFYGMKYDLIIMHKIALKDPNLSKIFGAEFVWILCPEAITPTMSVMNKKEKFSPSLELSEDMPPLPGVFGFAYAPTTSMLKDNLNIATSFWKTSVEXXXXXXXXXXXXXXXEILERMIPKLNCQSKVDRNDAWTFGKYIYKFMSTLSVDYNSN------FYQFSVHNYLNSTSFLVMNTRSILDKSPLYEMEKEKHFVTSWTKVGTWIMSSTLEE-KRTKLQIDGVTWPGEVNKPPLGRPSKFKLRVSTLKEEPFVIFS-VKQDKTCGNNALACSVLHDSLSISVDDFEKSKNRTKYLYMGNENYTDACCTGMAIDILRELMKDLNFEVDLYEVPDRKWGAWSAEKGWNGLLESLINRKVDMAVSAFKITPNRSEQVDFTVPFQETGIAILVALHEGSISPTAFLKPYDWASWMVILIFSVHCCSTAMFIYEWLSPKGLDRGNVPPREHKFSLFRALWLIWAMLFGASVNVDSPRGMASRFLGCIWALFGLVFLASYTANLAAFMIAKEDHYDLKGLNDWRFQRPWNFKPEFRFATVPFSASEENIALNYPDIALYMRRYNKSSVEEGIRALKQKEIDAFIYDSNVLEFRAAKDEGCKLRTVGNLYAVTGYGIAFPKGSKWYSKVNDLIMQYQKYDLLHRWKTFWLTGACKKTDKLANTNRTLGVRNFISAFXXXXXXXXXXXXXXXCEHLFFRYLRPRMSNLDQYGCCGLISLSMGQLLSFEQTVNQTVDFVKNYKCHNPLCENQIWRLRKELEMSKEIIRKLET 3121
            F G    SE+ +  +    +  YK  L  +   + RI + YG+  DL++++K A KD  L  +FG E+VW++ P AI       N K+ F+  LE       LPG+FGF Y P  S   +    A   W  ++      L   + +  + +L R+ P    +    R   W +GK+I K   T    Y  +      +  F+ +  +N+T F+++N+          +++K +   T W  VG+W MSS  E   RT  +ID V WPG    PP+GRP K+ +RV+TL+E+PF+ +  ++ D  CG  +L C V+  + S    +F  S         G+  Y   CC+G++ID+LRELMKDL+F+VDL+EVPD+KWG W+A+ GWNGL+  L+  K DM ++A KITPNRSEQ++F+VP+Q TGI ILVAL EG+IS  AFLKPYD+ SW +IL+FSVH C  A+F++EWLSP+GLDRGNVPPREHKFSLFR+LWLIW+MLFGA+VN D+PRG+ASRFLG IWALF LVFLASYTANLAAFMIA+E +YDL G+NDWR   P   +P FRFATVP  A+EEN+ +N+P +A YMR Y+KS+++EGI+ALK  EIDAFIYD+ VL++R  KD+ CKL+TVGN Y++TGYG+ FPKGS+W   ++  I+ Y+K  LL RW  +W TGAC+++ +L N+N+TLGV+NFISAFILL+ G+++  LLL+ EH F+RY+RPR+ + D+YGCCGL+S+SMGQLLSFEQ+VNQTVD +K++KC NP+CE Q W+LR ELE S+  ++KLET
Sbjct:  237 FPGINKLSEVRTCPEDSRCIWRYKSILRQLYNTEERIFILYGVSSDLMLLYKAA-KDTGLLHLFGNEYVWLVSPPAIVSPSE--NIKDGFTTGLEKEH----LPGLFGFYYTPDISKAAE---AAAYVWYEAMRKYKGQLLNSSRLDESTVLGRLHPNFTYKHSDYRRQFWEYGKHITKLAKTAGHCYRCDDIERREYIGFNSNGVINTTQFVLVNS----------QIKKNQ---TRWFPVGSWSMSSRHESPSRTSFRIDSVIWPGYSKTPPIGRPKKYLMRVATLEEDPFITYRPLEADGRCGETSLKCRVVMSNAS----EFHWSNADNITKLDGSGRYQFNCCSGLSIDLLRELMKDLDFDVDLFEVPDKKWGGWTAQ-GWNGLVRVLLEGKADMVLTALKITPNRSEQIEFSVPYQRTGITILVALREGAISTRAFLKPYDYPSWCLILVFSVHACGAALFLFEWLSPQGLDRGNVPPREHKFSLFRSLWLIWSMLFGAAVNADNPRGVASRFLGNIWALFALVFLASYTANLAAFMIAEESYYDLSGINDWRLMEPGMHRPPFRFATVPSGATEENVKMNFPQMAEYMRNYSKSNLDEGIKALKNHEIDAFIYDATVLQYRVGKDKDCKLKTVGNWYSMTGYGVGFPKGSEWKPDIDSQILIYRKNGLLERWSKYWFTGACQQSGRLRNSNQTLGVKNFISAFILLIGGMLLCCLLLLLEHWFYRYMRPRLKDFDKYGCCGLVSISMGQLLSFEQSVNQTVDLMKHHKCKNPICETQQWKLRHELETSRRRLQKLET 1012          

HSP 2 Score: 62.7734 bits (151), Expect = 5.706e-6
Identity = 37/100 (37.00%), Postives = 58/100 (58.00%), Query Frame = 3
Query:  423 VIEYFVNLISNLGVPTITWLPSQLGQILFEEGPMALRLEPSNKHLAEAMFDFVQTYNWXXXXXXXXXXXXXXXXFVQMLKEVITERESSSKDDYFKLKIV 722
             + YF+  I++LG+P  T+L + +GQ+  E+  + LRLEPS  H+A+A  DF+Q +NW    L+VS NL G    +Q +KE     +  +    FK +I 
Sbjct:  133 TVNYFLLNINSLGIPAFTYLANAVGQLESEKDSLCLRLEPSTWHVAQAFSDFLQEFNWEKATLIVSENLPGHAEMIQHMKESAESSQRLTDSSAFKFEIT 232          
BLAST of Glutamate receptor ionotropic, NMDA 2B vs. TrEMBL
Match: A0A267EW57 (Uncharacterized protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig014971g1 PE=3 SV=1)

HSP 1 Score: 793.882 bits (2049), Expect = 0.000e+0
Identity = 398/804 (49.50%), Postives = 546/804 (67.91%), Query Frame = 2
Query:  734 FDGFIDQSEIMSVLKSEERLSSYKKSLEHILAADHRIILFYGMKYDLIIMHKIALKDPNLSKIFGAEFVWILCPEAITPTMSVMNKKEKFSPSLELSEDMPPLPGVFGFAYAPTTSMLKDNLNIATSFWKTSVEXXXXXXXXXXXXXXXEILERMIPKLNCQSKVDRNDAWTFGKYIYKFMSTLSVDYNSN------FYQFSVHNYLNSTSFLVMNTRSILDKSPLYEMEKEKHFVTSWTKVGTWIMSSTLEE-KRTKLQIDGVTWPGEVNKPPLGRPSKFKLRVSTLKEEPFVIFS-VKQDKTCGNNALACSVLHDSLSISVDDFEKSKNRTKYLYMGNENYTDACCTGMAIDILRELMKDLNFEVDLYEVPDRKWGAWSAEKGWNGLLESLINRKVDMAVSAFKITPNRSEQVDFTVPFQETGIAILVALHEGSISPTAFLKPYDWASWMVILIFSVHCCSTAMFIYEWLSPKGLDRGNVPPREHKFSLFRALWLIWAMLFGASVNVDSPRGMASRFLGCIWALFGLVFLASYTANLAAFMIAKEDHYDLKGLNDWRFQRPWNFKPEFRFATVPFSASEENIALNYPDIALYMRRYNKSSVEEGIRALKQKEIDAFIYDSNVLEFRAAKDEGCKLRTVGNLYAVTGYGIAFPKGSKWYSKVNDLIMQYQKYDLLHRWKTFWLTGACKKTDKLANTNRTLGVRNFISAFXXXXXXXXXXXXXXXCEHLFFRYLRPRMSNLDQYGCCGLISLSMGQLLSFEQTVNQTVDFVKNYKCHNPLCENQIWRLRKELEMSKEIIRKLET 3121
            F G    SE+ +  +    +  YK  L  +   + RI + YG+  DL++++K A KD  L  +FG E+VW++ P AI       N K+ F+  LE       LPG+FGF Y P  S   +    A   W  ++      L   + +  + +L R+ P    +    R   W +GK+I K   T    Y  +      +  F+ +  +N+T F+++N+          +++K +   T W  VG+W MSS  E   RT  +ID V WPG    PP+GRP K+ +RV+TL+E+PF+ +  ++ D  CG  +L C V+  + S    +F  S         G+  Y   CC+G++ID+LRELMKDL+F+VDL+EVPD+KWG W+A+ GWNGL+  L+  K DM ++A KITPNRSEQ++F+VP+Q TGI ILVAL EG+IS  AFLKPYD+ SW +IL+FSVH C  A+F++EWLSP+GLDRGNVPPREHKFSLFR+LWLIW+MLFGA+VN D+PRG+ASRFLG IWALF LVFLASYTANLAAFMIA+E +YDL G+NDWR   P   +P FRFATVP  A+EEN+ +N+P +A YMR Y+KS+++EGI+ALK  EIDAFIYD+ VL++R  KD+ CKL+TVGN Y++TGYG+ FPKGS+W   ++  I+ Y+K  LL RW  +W TGAC+++ +L N+N+TLGV+NFISAFILL+ G+++  LLL+ EH F+RY+RPR+ + D+YGCCGL+S+SMGQLLSFEQ+VNQTVD +K++KC NP+CE Q W+LR ELE S+  ++KLET
Sbjct:  147 FPGINKLSEVRTCPEDSRCIWRYKSILRQLYNTEERIFILYGVSSDLMLLYKAA-KDTGLLHLFGNEYVWLISPPAIVSPSE--NIKDGFTTGLEKEH----LPGLFGFYYTPDISKAAE---AAAYVWYEAMRKYKGQLLNSSRLDESTVLGRLHPNFTYKHSDYRRQFWEYGKHITKLAKTAGHCYRCDDIERREYIGFNSNGVINTTQFVLVNS----------QIKKNQ---TRWFPVGSWSMSSRHESPSRTSFRIDSVIWPGYSKTPPIGRPKKYLMRVATLEEDPFITYRPLEADGRCGETSLKCRVVMSNAS----EFHWSNADNITKLDGSGRYQFNCCSGLSIDLLRELMKDLDFDVDLFEVPDKKWGGWTAQ-GWNGLVRVLLEGKADMVLTALKITPNRSEQIEFSVPYQRTGITILVALREGAISTRAFLKPYDYPSWCLILVFSVHACGAALFLFEWLSPQGLDRGNVPPREHKFSLFRSLWLIWSMLFGAAVNADNPRGVASRFLGNIWALFALVFLASYTANLAAFMIAEESYYDLSGINDWRLMEPGMHRPPFRFATVPSGATEENVKMNFPQMAEYMRNYSKSNLDEGIKALKNHEIDAFIYDATVLQYRVGKDKDCKLKTVGNWYSMTGYGVGFPKGSEWKPDIDSQILIYRKNGLLERWSKYWFTGACQQSGRLRNSNQTLGVKNFISAFILLIGGMLLCCLLLLLEHWFYRYMRPRLKDFDKYGCCGLVSISMGQLLSFEQSVNQTVDLMKHHKCKNPICETQQWKLRHELETSRRRLQKLET 922          
BLAST of Glutamate receptor ionotropic, NMDA 2B vs. TrEMBL
Match: A0A267G7X7 (Uncharacterized protein (Fragment) OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig034011g2 PE=3 SV=1)

HSP 1 Score: 764.607 bits (1973), Expect = 0.000e+0
Identity = 401/855 (46.90%), Postives = 553/855 (64.68%), Query Frame = 2
Query:  734 FDGFIDQSEIMSVLKSEERLSSYKKSLEHILAADHRIILFYGMKYDL-IIMHKIALKDPNLSKIFGAEFVWILCPEAITPTMSVMNKKEKFSPSLELSEDMPPLPGVFGFAYAPTTSMLKDNLNIATSFWKTSVEX-----XXXXXXXXXXXXXXEILERMIPKLNCQSKVDRNDAWTFGKYIYKFMSTLSVDYNSN------FYQFSVHNYLNSTSFLVMNTRSILDKSPLYEMEKEKHFVTSWTKVGTWIMSSTLEE-KRTKLQIDGVTWPGEVNKPPLGRPSKFKLRVSTLKEEPFVIFSVKQ---DKTCGNNALACSVLHDSLSISVDDFEKSKNRTKYLYMGNENYTDACCTGMAIDILRELMKDLNFEVDLYEVPDRKWGAWSAEKGWNGLLESLINRKVDMAVSAFKITPNRSEQVDFTVPFQETGIAILVALHEGSISPTAFLKPYDWASWMVILIFSVHCCSTAMFIYEWLSPKGLDRGNVPPREHKFSLFRALWLIWAMLFGASVNVDSPRGMASRFLGCIWALFGLVFLASYTANLAAFMIAKEDHYDLKGLNDWRFQRPWNFKPEFRFATVPFSASEENIALNYPDIALYMRRYNKSSVEEGIRALKQKEIDAFIYDSNVLEFRAAKDEGCKLRTVGNLYAVTGYGIAFPKGSKWYSKVNDLIMQYQKYDLLHRWKTFWLTGACKKTDKLANTNRTLGVRNFISAFXXXXXXXXXXXXXXXCEHLFFRYLRPRMSNLDQYGCCGLISLSMGQLLSFEQTVNQTVDFVKNYKCHNPLCENQIWRLRKELEMSKEIIRKLETSFEGLNSSLRSMSSFPKFVNQAEADNKNSASLLKSKEYHSFNN 3250
            FDG + Q   M        + +Y   L  +++ D RI   +G   DL +++H++ +K+     +F  +++WI+ P A+T   S +  K  F  +L        + G+F   Y    S L   + +A+  W  ++       L  ++    +++  +IL RM P   C +       W  GK I++     S  Y         +  F     LN+T F+++N+R    K   Y           W  VG W MSS  E    T   + GVTWPG  ++ PLGRP KF+LR +TLKE+PFV +   +    + C   +L C VL ++ S+       + N+++ L      YT +CC+G+AID+LRELMKDLNFEVDL+EVPD+KWG W+  + WNGL+  L+  + DM V++ KITPNRSEQ++F+VPF  TGI ILVAL EG+IS  AFLKPYD+ SW +IL+FSVH C  A+F++EWLSP+GLD+GNVPPREHKFSLFR+LWLIW+MLFGA+VN D+PRG+ASRFLG IWALF LVFLASYTANLAAFMIA+E +YDL G+NDWR + P + +P FRFATVP  A+EEN+ +NYPDIA +MR Y+KS+++EGIR LK  EIDAFIYD+ VL++R   DE CKL+TVGN Y++TGYGI  PKGSKW  ++N  I+ Y+   LL RW  +W+TGAC+++ KL NTN+TLGV+NFISAFILL+ G++   LLL+ EH F+R LRP++   D+YGCCGL+S+SMGQLLSFEQ+VNQTVD +K++KC NP+CE Q+W+LR EL+ +K  +++LE     LN  L++ +S  +   +A  D+  +      +EY    N
Sbjct:  239 FDG-VAQVSDMRRCNQTGCIRAYDSVLRRLVSGDDRIFFLHGNFADLRLLVHRVHIKNSRFGILFDKDYLWIVSPSAVTSPTSDL--KSGFDSNLGTIR----IAGLFALYY---DSNLVKAVTVASQLWFQALRQFKQRLLQQSVAAGGSLTNLDILRRMRPTFKCSNTTGL--FWPDGKEIFRLALNSSHCYECGNEDKREYIGFDRRGLLNTTEFVLLNSRPNSLKDSTY-----------WHPVGRWAMSSQHESLGGTSFDMQGVTWPGLASQAPLGRPKKFRLRAATLKEDPFVRYRPPEPPGSEACDPVSLPCRVLAENASLPDRYNWSAGNQSESL-----PYTASCCSGLAIDLLRELMKDLNFEVDLFEVPDKKWGGWTNNE-WNGLVRVLLEGQADMVVTSLKITPNRSEQIEFSVPFHRTGITILVALREGAISTKAFLKPYDYPSWCLILVFSVHACGAALFLFEWLSPQGLDKGNVPPREHKFSLFRSLWLIWSMLFGAAVNADNPRGVASRFLGNIWALFALVFLASYTANLAAFMIAEESYYDLSGINDWRLRDPTSHRPPFRFATVPSGATEENMRMNYPDIANHMRNYSKSNIDEGIRTLKTFEIDAFIYDATVLQYRVGNDEDCKLKTVGNWYSMTGYGIGLPKGSKWRHRINHRILSYRSSGLLERWSKYWITGACQQSGKLRNTNQTLGVKNFISAFILLIGGMLFCCLLLLLEHCFYRRLRPQLKKWDRYGCCGLVSISMGQLLSFEQSVNQTVDLIKHHKCQNPICETQLWKLRHELDTTKRKLQRLEGM---LNGRLQTATSTSENETRAVTDSAPTTIGNNGQEYLRITN 1061          
BLAST of Glutamate receptor ionotropic, NMDA 2B vs. TrEMBL
Match: A0A267F5H5 (Uncharacterized protein (Fragment) OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig034011g1 PE=3 SV=1)

HSP 1 Score: 764.222 bits (1972), Expect = 0.000e+0
Identity = 401/855 (46.90%), Postives = 550/855 (64.33%), Query Frame = 2
Query:  734 FDGFIDQSEIMSVLKSEERLSSYKKSLEHILAADHRIILFYGMKYDL-IIMHKIALKDPNLSKIFGAEFVWILCPEAITPTMSVMNKKEKFSPSLELSEDMPPLPGVFGFAYAPTTSMLKDNLNIATSFWKTSVEXXXXXXXXXXXXXXXE-----ILERMIPKLNCQSKVDRNDAWTFGKYIYKFMSTLSVDYNSN------FYQFSVHNYLNSTSFLVMNTRSILDKSPLYEMEKEKHFVTSWTKVGTWIMSSTLEE-KRTKLQIDGVTWPGEVNKPPLGRPSKFKLRVSTLKEEPFVIFSVKQ---DKTCGNNALACSVLHDSLSISVDDFEKSKNRTKYLYMGNENYTDACCTGMAIDILRELMKDLNFEVDLYEVPDRKWGAWSAEKGWNGLLESLINRKVDMAVSAFKITPNRSEQVDFTVPFQETGIAILVALHEGSISPTAFLKPYDWASWMVILIFSVHCCSTAMFIYEWLSPKGLDRGNVPPREHKFSLFRALWLIWAMLFGASVNVDSPRGMASRFLGCIWALFGLVFLASYTANLAAFMIAKEDHYDLKGLNDWRFQRPWNFKPEFRFATVPFSASEENIALNYPDIALYMRRYNKSSVEEGIRALKQKEIDAFIYDSNVLEFRAAKDEGCKLRTVGNLYAVTGYGIAFPKGSKWYSKVNDLIMQYQKYDLLHRWKTFWLTGACKKTDKLANTNRTLGVRNFISAFXXXXXXXXXXXXXXXCEHLFFRYLRPRMSNLDQYGCCGLISLSMGQLLSFEQTVNQTVDFVKNYKCHNPLCENQIWRLRKELEMSKEIIRKLETSFEGLNSSLRSMSSFPKFVNQAEADNKNSASLLKSKEYHSFNN 3250
            FDG + Q   M        + +Y   L  +++ D RI   +G   DL +++H++ +K+     +F  +++WI+ P A+T   S +  K  F  +L        + G+F   Y    S L   + +A+  W  ++      L  ++  +        IL RM P   C +       W  GK I++     S  Y         +  F     LN+T F+++N+R    K   Y           W  VG W MSS  E    T   + GVTWPG  ++ PLGRP KF+LR +TLKE+PFV +   +    + C   +L C VL ++ S+       + N+++ L      YT +CC+G+AID+LRELMKDLNFEVDL+EVPD+KWG W+  + WNGL+  L+  + DM V++ KITPNRSEQ++F+VPF  TGI ILVAL EG+IS  AFLKPYD+ SW +IL+FSVH C  A+F++EWLSP+GLD+GNVPPREHKFSLFR+LWLIW+MLFGA+VN D+PRG+ASRFLG IWALF LVFLASYTANLAAFMIA+E +YDL G+NDWR + P + +P FRFATVP  A+EEN+ +NYPDIA +MR Y+KS+++EGIR LK  EIDAFIYD+ VL++R   DE CKL+TVGN Y++TGYGI  PKGSKW  ++N  I+ Y+   LL RW  +W+TGAC+++ KL NTN+TLGV+NFISAFILL+ G++   LLL+ EH F+R LRP++   D+YGCCGL+S+SMGQLLSFEQ+VNQTVD +K++KC NP+CE Q+W+LR EL+ +K  +++LE     LN  L++ +S  +   +A  D+  +      +EY    N
Sbjct:  239 FDG-VAQVSDMRRCNQTGCIRAYDSVLRRLVSGDDRIFFLHGNFADLRLLVHRVHIKNSRFGILFDKDYLWIVSPSAVTSPTSDL--KSGFDSNLGTIR----IAGLFALYY---DSNLVKAVTVASQLWFQALRRFKQRLLQQSVAAGGSLTNLGILRRMRPTFKCSNTTGL--FWPDGKEIFRLALNSSHCYECGNEDKREYIGFDRRGLLNTTEFVLLNSRPNSLKDSTY-----------WHPVGRWAMSSQHESLGGTSFDMQGVTWPGLASQAPLGRPKKFRLRAATLKEDPFVRYRPPEPPGSEACDPVSLPCRVLAENASLPDRYNWSAGNQSESL-----PYTASCCSGLAIDLLRELMKDLNFEVDLFEVPDKKWGGWTNNE-WNGLVRVLLEGQADMVVTSLKITPNRSEQIEFSVPFHRTGITILVALREGAISTKAFLKPYDYPSWCLILVFSVHACGAALFLFEWLSPQGLDKGNVPPREHKFSLFRSLWLIWSMLFGAAVNADNPRGVASRFLGNIWALFALVFLASYTANLAAFMIAEESYYDLSGINDWRLRDPTSHRPPFRFATVPSGATEENMRMNYPDIAKHMRNYSKSNIDEGIRTLKTFEIDAFIYDATVLQYRVGNDEDCKLKTVGNWYSMTGYGIGLPKGSKWRHRINHRILSYRSSGLLERWSKYWITGACQQSGKLRNTNQTLGVKNFISAFILLIGGMLFCCLLLLLEHCFYRRLRPQLKKWDRYGCCGLVSISMGQLLSFEQSVNQTVDLIKHHKCQNPICETQLWKLRHELDTTKRKLQRLEGM---LNGRLQTATSTSENETRAVTDSAPTTIGNNGQEYLRITN 1061          
BLAST of Glutamate receptor ionotropic, NMDA 2B vs. TrEMBL
Match: A0A1I8JBQ4 (Uncharacterized protein OS=Macrostomum lignano OX=282301 PE=3 SV=1)

HSP 1 Score: 719.924 bits (1857), Expect = 0.000e+0
Identity = 363/753 (48.21%), Postives = 502/753 (66.67%), Query Frame = 2
Query:  734 FDGFIDQSEIMSVLKSEERLSSYKKSLEHILAADHRIILFYGMKYDLIIMHKIALKDPNLSKIFGAEFVWILCPEAITPTMSVMNKKEKFSPSLELSEDMPPLPGVFGFAYAPTTSMLKDNLNIATSFWKTSVEXXXXXXXXXXXXXXXEILERMIPKLNCQSKVDRNDAWTFGKYIYKFMSTLSVDYNSN------FYQFSVHNYLNSTSFLVMNTRSILDKSPLYEMEKEKHFVTSWTKVGTWIMSSTLEE-KRTKLQIDGVTWPGEVNKPPLGRPSKFKLRVSTLKEEPFVIF-SVKQDKTCGNNALACSVLHDSLSISVDDFEKSKNRTKYLYMGNENYTDACCTGMAIDILRELMKDLNFEVDLYEVPDRKWGAWSAEKGWNGLLESLINRKVDMAVSAFKITPNRSEQVDFTVPFQETGIAILVALHEGSISPTAFLKPYDWASWMVILIFSVHCCSTAMFIYEWLSPKGLDRGNVPPREHKFSLFRALWLIWAMLFGASVNVDSPRGMASRFLGCIWALFGLVFLASYTANLAAFMIAKEDHYDLKGLNDWRFQRPWNFKPEFRFATVPFSASEENIALNYPDIALYMRRYNKSSVEEGIRALKQKEIDAFIYDSNVLEFRAAKDEGCKLRTVGNLYAVTGYGIAFPKGSKWYSKVNDLIMQYQKYDLLHRWKTFWLTGACKKTDKLANTNRTLGVRNFISAFXXXXXXXXXXXXXXXCEHLFFRYLRPRMSNLDQYGCCGLISLS 2968
            F G    SE+ +  +    +  YK  L  +   + RI + YG+  DL++++K A KD  L  +FG E+VW++ P AI       N K+ F+  LE       LPG+FGF Y P  S   +    A   W  ++      L   + +  + +L R+ P    +    R   W +GK+I K   T    Y  +      +  F+ +  +N+T F+++N+          +++K +   T W  VG+W MSS  E   RT  +ID V WPG    PP+GRP K+ +RV+TL+E+PF+ +  ++ D  CG  +L C V+  + S    +F  S         G+  Y   CC+G++ID+LRELMKDL+F+VDL+EVPD+KWG W+A+ GWNGL+  L+  K DM ++A KITPNRSEQ++F+VP+Q TGI ILVAL EG+IS  AFLKPYD+ SW +IL+FSVH C  A+F++EWLSP+GLDRGNVPPREHKFSLFR+LWLIW+MLFGA+VN D+PRG+ASRFLG IWALF LVFLASYTANLAAFMIA+E +YDL G+NDWR   P   +P FRFATVP  A+EEN+ +N+P +A YMR Y+KS+++EGI+ALK  EIDAFIYD+ VL++R  KD+ CKL+TVGN Y++TGYG+ FPKGS+W   ++  I+ Y+K  LL RW  +W TGAC+++ +L N+N+TLGV+NFISAFILL+ G+++  LLL+ EH F+RY+RPR+ + D+YGCCGL+S+ 
Sbjct:   77 FPGINKLSEVRTCPEDSRCIWRYKSILRQLYNTEERIFILYGVSSDLMLLYKAA-KDTGLLHLFGNEYVWLISPPAIVSPSE--NIKDGFTTGLEKEH----LPGLFGFYYTPDISKAAE---AAAYVWYEAMRKYKGQLLNSSRLDESTVLGRLHPNFTYKHSDYRRQFWEYGKHITKLAKTAGHCYRCDDIERREYIGFNSNGVINTTQFVLVNS----------QIKKNQ---TRWFPVGSWSMSSRHESPSRTSFRIDSVIWPGYSKTPPIGRPKKYLMRVATLEEDPFITYRPLEADGRCGETSLKCRVVMSNAS----EFHWSNADNITKLDGSGRYQFNCCSGLSIDLLRELMKDLDFDVDLFEVPDKKWGGWTAQ-GWNGLVRVLLEGKADMVLTALKITPNRSEQIEFSVPYQRTGITILVALREGAISTRAFLKPYDYPSWCLILVFSVHACGAALFLFEWLSPQGLDRGNVPPREHKFSLFRSLWLIWSMLFGAAVNADNPRGVASRFLGNIWALFALVFLASYTANLAAFMIAEESYYDLSGINDWRLMEPGMHRPPFRFATVPSGATEENVKMNFPQMAEYMRNYSKSNLDEGIKALKNHEIDAFIYDATVLQYRVGKDKDCKLKTVGNWYSMTGYGVGFPKGSEWKPDIDSQILIYRKNGLLERWSKYWFTGACQQSGRLRNSNQTLGVKNFISAFILLIGGMLLCCLLLLLEHWFYRYMRPRLKDFDKYGCCGLVSIG 801          
BLAST of Glutamate receptor ionotropic, NMDA 2B vs. Ensembl Cavefish
Match: grin2ca (glutamate receptor ionotropic, NMDA 2C-like [Source:NCBI gene;Acc:103025257])

HSP 1 Score: 329.331 bits (843), Expect = 2.788e-93
Identity = 214/666 (32.13%), Postives = 353/666 (53.00%), Query Frame = 2
Query: 1211 NCQS--KVDRNDAWTFGKYIYKFMSTLSVDYNSNFYQFSVHNYLNSTSFLVMNTRSILDKSPLYEMEKEKHFVTSWTKVGTWIMSSTLEEKRTKLQIDGVTWP--GEVNKPPLGRPSKFKLRVSTLKEEPFVIFSVKQ--DKTCGNNALACSVLHDSLSISVDDFEKSKNRTKYLYMGNENYTDACCTGMAIDILRELMKDLNFEVDLYEVPDRKWGAWSAEKGWNGLLESLINRKVDMAVSAFKITPNRSEQVDFTVPFQETGIAILVALHEGSISPTAFLKPYDWASWMVILIFSVHCCSTAMFIYEWLSPKGLDRGNVP---PREHKFSLFRALWLIWAMLFGASVNVDSPRGMASRFLGCIWALFGLVFLASYTANLAAFMIAKEDHYDLKGLNDWRFQRPWNFKPEFRFATVPFSASEENIALNYPDIALYMRRYNKSSVEEGIRALKQKEIDAFIYDSNVLEFRAAKDEGCKLRTVGN--LYAVTGYGIAFPKGSKWYSKVNDLIMQYQKYDLLHRWKTFWLTGACKKTDKLANTNRTLGVRNFISAFXXXXXXXXXXXXXXXCEHLFFRYLRPRMSNLDQYGCCGLISLSMGQLLSF---EQTVN----QTVDFVKNYKCHNPLCENQIWRLRKELEMSKEIIR--KLETSFEGLNSSL 3148
            +CQ+  + D ND          F   L+V +    + F+   YL + + +++             +++E+     W KVG +        +   LQ+    WP  G   +P         L V+TL+E PFVI         TC +N + C               +  N+T+ +    E YT  CC G  IDIL++L +++ F  DLY V + K G       WNG++  ++ ++ DMA+ +  I   RSE +DF+VPF ETGI+++VA   G++SP+AFL+PY  A W+++ +  +   +  +F++E+ SP G +R  V    P    F++ +++WL+W ++F  SV +++P+G  S+ +  +WA F ++FLASYTANLAAFMI ++    + GL+D +FQ+P    P FRF TVP  ++E NI  NYP++  +M +YN+  VE+ + +LK  ++DAFIYD+ VL + A KDEGCKL T+G+  ++A TGYGIA  KGS+W   ++  ++Q+       + +T WLTG C+   K   +++ L + N    F +LL  + +S L+   EHL +  LR  +   ++     L+++S G    F   E+T +    Q+ D   NY   N L         K L+ +K+I+   ++E S +    ++
Sbjct:  330 DCQTPLRPDTNDTL--------FTHMLNVTWEHTDFSFNSDGYLVNPAMIIIT------------LDRERQ----WDKVGRY--------ESGILQMRYPVWPRYGTYLEP---VSDNRHLTVATLEERPFVIVEAVDPVTGTCLSNTVPC--------------RRQSNKTETIIGHTEPYTKLCCKGFCIDILKKLSRNIKFSYDLYLVTNGKHGKL-VRGVWNGMIGEVVYKRADMAIGSLTINEERSEIIDFSVPFVETGISVMVARSNGTVSPSAFLEPYSPAVWVMMFVMCLTVVAVTVFVFEYCSPVGYNRSLVSAKDPGGPTFTIGKSVWLLWGIVFNNSVPIENPKGTTSKIMVLVWAFFAVIFLASYTANLAAFMIQEQYIDTVSGLSDKKFQKPQEQYPPFRFGTVPNGSTERNIRSNYPEMHSHMVKYNQKGVEDALNSLKTGKLDAFIYDAAVLNYMAGKDEGCKLVTIGSGKVFATTGYGIALQKGSRWKRPIDLALLQFLADGDTQKLQTVWLTGICRNEKKEVMSSK-LDIDNMAGVFYMLLVAMGLSLLVFAWEHLLYWKLRHSVRRSERLDF--LLAISRGIYSCFNGVEETDHNGSMQSPDVTTNYTQANML---------KMLKTAKDIVSSARVENSLDNATKTI 933          
BLAST of Glutamate receptor ionotropic, NMDA 2B vs. Ensembl Cavefish
Match: grin2cb (glutamate receptor ionotropic, NMDA 2C [Source:NCBI gene;Acc:103046826])

HSP 1 Score: 327.791 bits (839), Expect = 4.076e-93
Identity = 193/550 (35.09%), Postives = 306/550 (55.64%), Query Frame = 2
Query: 1559 LRVSTLKEEPFVIFSV--KQDKTCGNNALACSVLHDSLSISVDDFEKSKNRTKYLYMGNENYTDACCTGMAIDILRELMKDLNFEVDLYEVPDRKWGAWSAEKGWNGLLESLINRKVDMAVSAFKITPNRSEQVDFTVPFQETGIAILVALHEGSISPTAFLKPYDWASWMVILIFSVHCCSTAMFIYEWLSPKGLDRGNV---PPREHKFSLFRALWLIWAMLFGASVNVDSPRGMASRFLGCIWALFGLVFLASYTANLAAFMIAKEDHYDLKGLNDWRFQRPWNFKPEFRFATVPFSASEENIALNYPDIALYMRRYNKSSVEEGIRALKQKEIDAFIYDSNVLEFRAAKDEGCKLRTVGN--LYAVTGYGIAFPKGSKWYSKVNDLIMQYQKYDLLHRWKTFWLTGACKKTDKLANTNRTLGVRNFISAFXXXXXXXXXXXXXXXCEHLFFRYLRPRMSNLDQYGCCGLISLSMGQLLSFEQTVN-------QTVDFVKNYKCHNPLCENQIWRLRKELEMSKEIIR--KLETSFEGLNSSLRSMS 3160
            L V+TL+E PFVI         TC  N + C               +  N+T+ ++  +E YT  CC G  IDIL++L + + F  DLY V + K G       WNG++  +  ++ DMA+ +  I   RSE +DF+VPF ETGI+++VA   G++SP+AFL+PY  A W+++ +  +   +  +F++E+ SP G +R  V    P    F++ +++WL+W ++F  SV +++P+G  S+ +  +WA F ++FLASYTANLAAFMI ++    + GL+D +FQ+P    P FRF TVP  ++E NI  NYPD+  +M +YN+  VEE + +LK  ++DAFIYD+ VL + A KDEGCKL T+G+  ++A TGYGIA  K S+W   ++  ++Q+       R +T WL+G C+  +K    +  L + N    F +LL  + +S L+   EHL +  LR  +   ++     L+++S G    F    +       Q  D   NY   N L         K L+ +K+I+   K+E S +    ++ + S
Sbjct:  410 LTVATLEERPFVIVESVDPATGTCVRNTVPC--------------RRQANKTEAVFGHSEPYTKLCCKGFCIDILKKLSRTIKFSYDLYLVTNGKHGKL-VRGTWNGMIGEVFYKRADMAIGSLTINEERSEIIDFSVPFVETGISVMVARSNGTVSPSAFLEPYSPAVWVMMFVMCLTVVAVTVFVFEYFSPVGYNRSLVSAKAPGGPTFTIGKSVWLLWGIVFNNSVPIENPKGTTSKIMVLVWAFFAVIFLASYTANLAAFMIQEQYIDTVSGLSDKKFQKPQEHYPPFRFGTVPNGSTERNIRSNYPDMHTHMMKYNQKGVEEALNSLKTGKLDAFIYDAAVLNYMAGKDEGCKLVTIGSGKVFATTGYGIALQKDSRWKRPIDLALLQFLGDGDTQRLETVWLSGICQN-EKNEVMSSKLDIDNMAGVFYMLLVAMGLSLLVFAWEHLLYWKLRHSVHKSERLDF--LLAISRGIYSCFNGVEDVGRSGNMQNPDITTNYAQANML---------KMLQTAKDIVSSAKVENSLDNATKTIENWS 932          
BLAST of Glutamate receptor ionotropic, NMDA 2B vs. Ensembl Cavefish
Match: grin2cb (glutamate receptor ionotropic, NMDA 2C [Source:NCBI gene;Acc:103046826])

HSP 1 Score: 320.857 bits (821), Expect = 7.015e-91
Identity = 193/550 (35.09%), Postives = 302/550 (54.91%), Query Frame = 2
Query: 1559 LRVSTLKEEPFVIFSV--KQDKTCGNNALACSVLHDSLSISVDDFEKSKNRTKYLYMGNENYTDACCTGMAIDILRELMKDLNFEVDLYEVPDRKWGAWSAEKGWNGLLESLINRKVDMAVSAFKITPNRSEQVDFTVPFQETGIAILVALHEGSISPTAFLKPYDWASWMVILIFSVHCCSTAMFIYEWLSPKGLDRGNV---PPREHKFSLFRALWLIWAMLFGASVNVDSPRGMASRFLGCIWALFGLVFLASYTANLAAFMIAKEDHYDLKGLNDWRFQRPWNFKPEFRFATVPFSASEENIALNYPDIALYMRRYNKSSVEEGIRALKQKEIDAFIYDSNVLEFRAAKDEGCKLRTVGN--LYAVTGYGIAFPKGSKWYSKVNDLIMQYQKYDLLHRWKTFWLTGACKKTDKLANTNRTLGVRNFISAFXXXXXXXXXXXXXXXCEHLFFRYLRPRMSNLDQYGCCGLISLSMGQLLSFEQTVN-------QTVDFVKNYKCHNPLCENQIWRLRKELEMSKEIIR--KLETSFEGLNSSLRSMS 3160
            L V+TL+E PFVI         TC  N + C               +  N+T       E YT  CC G  IDIL++L + + F  DLY V + K G       WNG++  +  ++ DMA+ +  I   RSE +DF+VPF ETGI+++VA   G++SP+AFL+PY  A W+++ +  +   +  +F++E+ SP G +R  V    P    F++ +++WL+W ++F  SV +++P+G  S+ +  +WA F ++FLASYTANLAAFMI ++    + GL+D +FQ+P    P FRF TVP  ++E NI  NYPD+  +M +YN+  VEE + +LK  ++DAFIYD+ VL + A KDEGCKL T+G+  ++A TGYGIA  K S+W   ++  ++Q+       R +T WL+G C+  +K    +  L + N    F +LL  + +S L+   EHL +  LR  +   ++     L+++S G    F    +       Q  D   NY   N L         K L+ +K+I+   K+E S +    ++ + S
Sbjct:  400 LTVATLEERPFVIVESVDPATGTCVRNTVPC--------------RRQANKT-------EPYTKLCCKGFCIDILKKLSRTIKFSYDLYLVTNGKHGKL-VRGTWNGMIGEVFYKRADMAIGSLTINEERSEIIDFSVPFVETGISVMVARSNGTVSPSAFLEPYSPAVWVMMFVMCLTVVAVTVFVFEYFSPVGYNRSLVSAKAPGGPTFTIGKSVWLLWGIVFNNSVPIENPKGTTSKIMVLVWAFFAVIFLASYTANLAAFMIQEQYIDTVSGLSDKKFQKPQEHYPPFRFGTVPNGSTERNIRSNYPDMHTHMMKYNQKGVEEALNSLKTGKLDAFIYDAAVLNYMAGKDEGCKLVTIGSGKVFATTGYGIALQKDSRWKRPIDLALLQFLGDGDTQRLETVWLSGICQN-EKNEVMSSKLDIDNMAGVFYMLLVAMGLSLLVFAWEHLLYWKLRHSVHKSERLDF--LLAISRGIYSCFNGVEDVGRSGNMQNPDITTNYAQANML---------KMLQTAKDIVSSAKVENSLDNATKTIENWS 915          
BLAST of Glutamate receptor ionotropic, NMDA 2B vs. Ensembl Cavefish
Match: grin2da (glutamate receptor ionotropic, NMDA 2D-like [Source:NCBI gene;Acc:103040794])

HSP 1 Score: 322.398 bits (825), Expect = 2.035e-90
Identity = 180/482 (37.34%), Postives = 279/482 (57.88%), Query Frame = 2
Query: 1559 LRVSTLKEEPFVIFSVKQDKT--CGNNALACSVLHDSLSISVDDFEKSKNRTKYLYMGNENYTDACCTGMAIDILRELMKDLNFEVDLYEVPDRKWGAWSAEKGWNGLLESLINRKVDMAVSAFKITPNRSEQVDFTVPFQETGIAILVALHEGSISPTAFLKPYDWASWMVILIFSVHCCSTAMFIYEWLSPKGLDRGNVPPRE---HKFSLFRALWLIWAMLFGASVNVDSPRGMASRFLGCIWALFGLVFLASYTANLAAFMIAKEDHYDLKGLNDWRFQRPWNFKPEFRFATVPFSASEENIALNYPDIALYMRRYNKSSVEEGIRALKQKEIDAFIYDSNVLEFRAAKDEGCKLRTVGN--LYAVTGYGIAFPKGSKWYSKVNDLIMQYQKYDLLHRWKTFWLTGACKKTDKLANTNRTLGVRNFISAFXXXXXXXXXXXXXXXCEHLFF---RYLRPRMSNLD--------QYGCC 2950
            LRV TL+E PFVI       T  C  +++ C +  ++ S+ VD  +  K+               CC G  ID+L+ L K + F  DLY V + + G  +    WNG++  +++++ DMA+ +  I   RSE V+F+VPF ETGI+++V+   G++SP+AFL+PY  A W+++ +  +   +  +FI+E+ SP G +R     ++    KF++ +++WL+WA++F  SV V++PRG  S+ +  +WA F ++FLASYTANLAAFMI +E    + GL+D +FQ+P    P  RF TVP  ++EENI  NYP++  +M R N+  VEE I  LK  ++DAFIYD+ VL + A KDEGCK+ T+G+  ++A TGYGIA  K S+W   ++  ++Q    D +   +  WL+G C   DK+   +  L + N    F +LL  + +S L+   EHL +   R+   R   LD         Y CC
Sbjct:  351 LRVVTLEERPFVIVEPADPGTGSCIRDSVPCRLPLNTSSVVVDGIQSMKH---------------CCKGFCIDVLKRLAKIVGFTYDLYLVTNGRHGK-NINGEWNGMVGEVVSKRADMAIGSLTINEERSEVVEFSVPFVETGISVMVSRSNGTVSPSAFLEPYSPAVWVMMFVMCLSVVAVTVFIFEFFSPVGYNRSLQSGKKAGGSKFTIGKSIWLLWALVFNNSVPVENPRGTTSKIMVLVWAFFAVIFLASYTANLAAFMIQEEYIDTVSGLSDKKFQQPAEQYPPLRFGTVPNGSTEENIRSNYPNMHQFMVRNNQRGVEEAIDNLKTGKLDAFIYDAAVLNYMARKDEGCKVMTIGSGKVFATTGYGIALDKNSRWKRPLDLALLQLVGDDEIDMLERLWLSGIC-HNDKIEVMSSKLDIDNMAGVFYMLLVAMGLSLLVFAWEHLVYWKLRHCLGRSKGLDFLLAFSRGMYSCC 815          
BLAST of Glutamate receptor ionotropic, NMDA 2B vs. Ensembl Cavefish
Match: grin2ab (glutamate receptor, ionotropic, N-methyl D-aspartate 2A, b [Source:ZFIN;Acc:ZDB-GENE-070424-223])

HSP 1 Score: 320.087 bits (819), Expect = 3.435e-90
Identity = 178/488 (36.48%), Postives = 277/488 (56.76%), Query Frame = 2
Query: 1559 LRVSTLKEEPFVIFSVKQ--DKTCGNNALACSVLHDSLSISVDDFEKSKNRTKYLYMGNENYTDACCTGMAIDILRELMKDLNFEVDLYEVPDRKWGAWSAEKGWNGLLESLINRKVDMAVSAFKITPNRSEQVDFTVPFQETGIAILVALHEGSISPTAFLKPYDWASWMVILIFSVHCCSTAMFIYEWLSPKGLDRG---NVPPREHKFSLFRALWLIWAMLFGASVNVDSPRGMASRFLGCIWALFGLVFLASYTANLAAFMIAKEDHYDLKGLNDWRFQRPWNFKPEFRFATVPFSASEENIALNYPDIALYMRRYNKSSVEEGIRALKQKEIDAFIYDSNVLEFRAAKDEGCKLRTVGN--LYAVTGYGIAFPKGSKWYSKVNDLIMQYQKYDLLHRWKTFWLTGACKKTDKLANTNRTLGVRNFISAFXXXXXXXXXXXXXXXCEHLFFRYLRPRMSNLDQYGCCGLISLSMGQLLSFEQTV 3001
            L + TL+E+PFVI         TC  N++ C              +  K+ T        +Y   CC G  IDIL+++ +++ F  DLY V + K G       WNG++  ++ +K  MAV +  I   RSE +DF+VPF ETGI+++V+   G++SP+AFL+P+  + W+++ +  +   + A+F++E++SP G +R       P    F++ +A+WL+W ++F  SV V +PRG  S+F+  +WA F ++FLASYTANLAAFMI +E    + GL+D +FQ P++F P FRF TVP  ++E NI  NYPD+  YM +Y+++ V++ + +LK  ++DAFIYD+ VL + A +D+GCKL T+G+  ++A TGYGIA  KGS W   V+  I+       +   +  WLTG C   +K    +  L V N    F +L   + +S +    EHLF+  LR        Y   GL S   G L +  + +
Sbjct:  383 LSIVTLEEKPFVIVDDVDILTGTCMRNSVPCR-------------KHIKDNTT-----GGSYVKQCCKGFCIDILKKIARNVKFTYDLYLVTNGKHGK-KINNVWNGMVGEVVYKKAVMAVGSLTINEERSEVIDFSVPFVETGISVMVSRSNGTVSPSAFLEPFSASVWVMMFVMLLIVTAIAVFLFEFISPLGFNRNLAQGKDPHGPSFTIGKAVWLLWGLVFNNSVPVQNPRGTTSKFIVSVWAFFAVIFLASYTANLAAFMIQEEFVDQVTGLSDRKFQSPYSFSPPFRFGTVPNGSTERNIRKNYPDMHQYMVKYHQTGVQDALVSLKTGKLDAFIYDAAVLNYMAGRDDGCKLVTIGSGYIFATTGYGIALQKGSYWKRLVDLAILGIIGDGEMEELEAQWLTGICHN-EKNEVMSSQLDVDNMAGVFYMLAAAMALSLITFAWEHLFYWRLR--------YCFTGLCSGRPGLLFTISRGI 842          
BLAST of Glutamate receptor ionotropic, NMDA 2B vs. Ensembl Sea Lamprey
Match: ENSPMAT00000010716.1 (pep scaffold:Pmarinus_7.0:GL476465:413535:454465:1 gene:ENSPMAG00000009705.1 transcript:ENSPMAT00000010716.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 309.301 bits (791), Expect = 1.627e-90
Identity = 161/406 (39.66%), Postives = 251/406 (61.82%), Query Frame = 2
Query: 1736 YTDACCTGMAIDILRELMKDLNFEVDLYEVPDRKWGAWSAEKGWNGLLESLINRKVDMAVSAFKITPNRSEQVDFTVPFQETGIAILVALHEGSISPTAFLKPYDWASWMVILIFSVHCCSTAMFIYEWLSPKGLDRGNVPPREH---KFSLFRALWLIWAMLFGASVNVDSPRGMASRFLGCIWALFGLVFLASYTANLAAFMIAKEDHYD-LKGLNDWRFQRPWNFKPEFRFATVPFSASEENIALNYPDIALYMRRYNKSSVEEGIRALKQKEIDAFIYDSNVLEFRAAKDEGCKLRTVGN--LYAVTGYGIAFPKGSKWYSKVNDLIMQYQKYDLLHRWKTFWLTGAC--KKTDKLANTNRTLGVRNFISAFXXXXXXXXXXXXXXXCEHLFFRYLRPRMSN 2929
            Y   CC G  IDIL++L K + F  DLY V + K G+      WNG++  ++N +  MAV +  I   RSE VDF+VPF ETGI+++V    G++SP+AFL+P+    W+++ I  +     A+FI+E+ SP G +R     +E     F++ +++WL+WA++F  SV V++PRG  S+F+  +WA F ++FLASYTANLAAFMI +ED+ D + GL+D +FQ P    P FRF TVP  ++E NI  NY  +  YM ++++ SVE+ + +LK  ++DAFIYD+ VL + A KDEGC+L T+G+  ++  TGYGIA  K S+W   ++  ++Q+     +   +  WLTG C  ++ D +++    L + N    F +LL  + +S ++ +CEH F+   R  + N
Sbjct:  391 YVKKCCKGFCIDILKKLSKTVKFTYDLYLVTNGKHGS-KINGVWNGMIGEVVNMRAHMAVGSLTINEERSEVVDFSVPFVETGISVMVPRSNGTVSPSAFLEPFSADVWVMMFILCLLVSGIAVFIFEYFSPVGYNRQLSAGKEFGGPAFTIGKSIWLLWAIVFNNSVPVENPRGTTSKFMVSVWAFFAVIFLASYTANLAAFMI-QEDYIDQVSGLSDKKFQSPLEHSPPFRFGTVPNGSTERNIRNNYLQMHGYMSKFHQKSVEDALMSLKAGKLDAFIYDAAVLNYMAGKDEGCRLVTIGSGKVFVATGYGIALQKSSRWKRAIDLALLQFIGDGEMDELEMIWLTGICHGERNDVMSS---QLDIDNMAGVFYMLLVAMGLSFIVFVCEHFFYHVGRHCVKN 791          
BLAST of Glutamate receptor ionotropic, NMDA 2B vs. Ensembl Sea Lamprey
Match: ENSPMAT00000000889.1 (pep scaffold:Pmarinus_7.0:GL476542:184998:205948:1 gene:ENSPMAG00000000813.1 transcript:ENSPMAT00000000889.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 122.865 bits (307), Expect = 1.069e-31
Identity = 69/198 (34.85%), Postives = 108/198 (54.55%), Query Frame = 2
Query: 1559 LRVSTLKEEPFVIFSVKQ--DKTCGNNALACSVLHDSLSISVDDFEKSKNRTKYLYMGNENYTDACCTGMAIDILRELMKDLNFEVDLYEVPDRKWGAWSAEKGWNGLLESLINRKVDMAVSAFKITPNRSEQVDFTVPFQETGIAILVALHEGSISPTAFLKPYDWASWMVILIFSVHCCSTAMFIYEWLSPKGLDR 2146
            L + TL+E PFVI         TC  + +AC        I++ D    K+           Y   CC G  IDILR+L   + F  DLY V + K G    +  WNG++  +  ++  MAV +  I   RS+ VDF+VPF ETGI+++V+   G++SP+AFL+P+  A W+++ I  +   + A++++E+LSP G +R
Sbjct:   36 LSIVTLEERPFVIVENVDALTGTCMRSTVACR-----QEINMTDTSGDKS----------PYVKRCCKGFCIDILRKLSTTVRFTYDLYLVVNGKHGK-KIQGVWNGMVGEVEQKRAHMAVGSLTINEERSQVVDFSVPFVETGISVMVSRSNGTVSPSAFLEPFSAAVWVMMFILCLMLSAIAVWLFEYLSPVGFNR 217          
BLAST of Glutamate receptor ionotropic, NMDA 2B vs. Ensembl Sea Lamprey
Match: gria1b (glutamate receptor, ionotropic, AMPA 1b [Source:ZFIN;Acc:ZDB-GENE-020125-2])

HSP 1 Score: 119.013 bits (297), Expect = 4.353e-28
Identity = 104/395 (26.33%), Postives = 170/395 (43.04%), Query Frame = 2
Query: 1718 YMGNENYTDACCTGMAIDILRELMKDLNFEVDLYEVPDRKWGAWSAE-KGWNGLLESLINRKVDMAVSAFKITPNRSEQVDFTVPFQETGIAILVALHEGSISPT-AFLKPYDWASWMVILIFSVHCCSTAMFIYEWLSPKGLDRGN---------------------------------VPPREHKFSLFRALWLIWAMLFGASVNVDSPRGMASRFLGCIWALFGLVFLASYTANLAAFMIAKEDHYDLKGLNDWRFQRPWNFKPEFRFATVPFSASEE-----NIALNYPDIALYMR--------RYNKSSVEEGIRALKQKEIDAFIYDSNVLEFRAAKDEGCKLRTVGNLYAVTGYGIAFPKGSKWYSKVNDLIMQYQKYDLLHRWKTFW 2758
            + GN+ Y   C     +D+ +E+     FE     VPD  +GA + + K WNG++  L+  + D+A++   I+  R E +DF+ PF   GI+I++   + S     +FL P  +  WM I IF+    S  +F+    SP    R +                                  PP E  F +F +LW            + SPR ++ R +G +W  F L+ ++SYTANLAAF+  +     ++  +D   Q       E  + T+   +++E      I + Y  + L+M+        R N   V    R  K K   A++ +S   E+   +     ++  GNL +  GYGIA PKGS     VN  +++  +  LL + K  W
Sbjct:   53 FEGNDKYEGYC-----VDLGQEIAIHEQFEYKWSVVPDGAYGARNPDTKVWNGMVGELVYGRADIAIAPLTISLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVISFLDPLAYEIWMCI-IFAYIGVSVVLFLVSRFSPYEWQRDDDTDVEPNGNGGAGGGGGGGGSGGGAGGGSGGGGEPPNE--FGIFNSLWFSLGAFMQQGCEI-SPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESADDLAKQT------EIAYGTLDSGSTKEFFQRSKIGV-YEKMWLFMKDAEPKVFVRTNADGVS---RVRKSKGKYAYLLESTTNEYTEQRKPCDTMKVGGNLDS-KGYGIATPKGSALRDAVNLAVLKLNEQGLLDKLKNKW 427          
BLAST of Glutamate receptor ionotropic, NMDA 2B vs. Ensembl Sea Lamprey
Match: ENSPMAT00000005084.1 (pep scaffold:Pmarinus_7.0:GL476900:54926:87395:-1 gene:ENSPMAG00000004612.1 transcript:ENSPMAT00000005084.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 108.997 bits (271), Expect = 5.563e-26
Identity = 93/333 (27.93%), Postives = 150/333 (45.05%), Query Frame = 2
Query: 1883 SLINRKVDMAVSAFKITPNRSEQVDFTVPFQETGIAILVALHEGSISPT--AFLKPYDWASWMVILI--FSVHCCSTAMFI------YEWLSPKGLDRGNVPPREHKFSLFRALWLIWAMLFGASVNVDSPRGMASRFLGCIWALFGLVFLASYTANLAAFMIAKEDHYDLKGLNDWRFQRPWNFKPEFRFATVPFSASEENIALNYPDIALYMRRYNKSSV---EEGIRALKQKEIDAFIYDSNVLEFRAAKDEGCKLRTVGNLYAVTGYGIAFPKGSKWYSKVNDLIMQYQKYDLLHRWKTFWLTG-ACKKTDKLANTNRTLGVRNFISAF 2839
            S  N K D+AV+   I   R + +DF+ PF   GI+IL     G+ +P   +FL P     WM IL+    V C    +F+      YEW +P   +  +    E+ F++  + W     L      +  P+ +++R +G IW  F L+ ++SYTANLAAF+  +     +   +D   Q    +      +T+ F    +     Y  +  +M     + +   EEGI+ +   +  A + +S  +E+   ++  C L  +G L    GYGI  P GS +  K+   I+Q Q+   LH  K  W  G  C + D  +N    LGV+N    F
Sbjct:    4 SRTNHKADLAVAPLTINYMREKAIDFSKPFMTLGISILYRKPNGT-NPGIFSFLNPLSPDIWMYILLAYLGVSCV---LFVIARFSPYEWYNPHPCNP-DSDVVENNFTMLNSFWFGVGALMQQGSEL-MPKALSTRIVGGIWWFFTLIIISSYTANLAAFLTVERMESPISSADDLAKQTRIEYGAVRDGSTMTFFKKSK--ISTYEKMWAFMSSRQTALIKNNEEGIQRVLTTDY-AMLMESTNIEYVTQRN--CNLTQIGGLIDNKGYGIGTPLGSPYRDKITIAILQLQEEGKLHMMKEKWWRGNGCPEED--SNEASALGVQNIGGIF 323          
BLAST of Glutamate receptor ionotropic, NMDA 2B vs. Ensembl Sea Lamprey
Match: ENSPMAT00000000621.1 (pep scaffold:Pmarinus_7.0:GL479810:19620:30867:-1 gene:ENSPMAG00000000562.1 transcript:ENSPMAT00000000621.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 79.7221 bits (195), Expect = 7.038e-17
Identity = 53/194 (27.32%), Postives = 94/194 (48.45%), Query Frame = 2
Query: 1757 GMAIDILRELMKDLNFEVDLYEVPDRKWGAWSAEKGWNGLLESLINRKVDMAVSAFKITPNRSEQVDFTVPFQETGIAILVALHEGSISPTAFLKPYDWASWMVILIFSVHCCSTAMFIYEWLSPKGLDRGNVPPREHKFSLFRALWLIWAMLFGASVNVDSPRGMASRFLGCIWALFGLVFLASYTANLAAFM 2338
            G ++D++  L K L F  +++   D  +G   A+  W+G++  L+N++ D+A+SA  ITP R   VDFT  + +  + +       S    A L P + A+W   L  +V      +++   ++P+   R       H  SL  +LWL++         + S    A   +G +W LF  + ++SYTA+L A +
Sbjct:   22 GFSVDVMDALSKSLGFSYEIFMPADLSYGLPQADGTWSGMIGELLNKRADVAISALTITPERESVVDFTKRYMDYSVGVAARRPADSAGLFALLSPLEPATW-ACLGLAVGLVGLLVYLLNRVTPRREPR-------HSPSLPASLWLVYGSFMQQGPELSSSSLSARLVMG-VWWLFAFIVVSSYTASLTALL 206          
BLAST of Glutamate receptor ionotropic, NMDA 2B vs. Ensembl Nematostella
Match: EDO35545 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SL56])

HSP 1 Score: 219.164 bits (557), Expect = 7.530e-59
Identity = 141/456 (30.92%), Postives = 230/456 (50.44%), Query Frame = 2
Query: 1496 DGVTWPGEVNKPPLGRPSKFKLRVSTLKEEPFVIFSVKQDKTCGNNALACSVLHDSLSISVDDFEKSKNRTKYLYMGNENYTDACCTGMAIDILRELMKDLNFEVDLYEVPDRKWGAW-----SAEKGWNGLLESLINRKVDMAVSAFKITPNRSEQVDFTVPFQETGIAILVALHEGSISPTAFLKPYDWASWMVILIFSVHCCSTAMFIYEWLSPKG-LDRGNVPPREHKFSLFRALWLIWAMLFGASVNVDSPRGMASRFLGCIWALFGLVFLASYTANLAAFMIAKEDHYDLKGLNDWRFQRPWNFKPEFRFATVPFSASEENI--ALNYPDIALYMRRYNKSSVEEGIRALKQKEIDAFIYDSNVLEFRAAKDEGCKLRTVGNLYAVTGYGIAFPKGSKWYSKVNDLIMQYQKYDLLHRWKTFWLTGACKKTDKLANTNRTLGVRNFISAF 2839
            + + WPG +N  P G      LRV TL  EPFV   VK   T G     CS L  + +  V            L  G  + TD   +G  +D+L  L + +NF   +    D  +G+      S  K WNG++  +I  K D+ V+A  I   R+E ++F+ PF+  G+ ILV  +E S S  +FL+P+    W+++L+ SVH  +  +++ +  SP G          E   +L  A+W  W +L  + +   +PR  ++R LG +WA F ++ +ASYTANLAAF++       + G++D   + P     +F +ATV  S+ +      +    +  +M  YN  + +EGI  +K  E+ AFI+DS VL + A+KD  C L T G L+  +GYGI  PKGS W + ++  I+ + +  ++   +T W+  +   T+    +  TLG+++ +  F
Sbjct:  375 ESIIWPGNLNTTPTGVFLSNHLRVVTLVGEPFVY--VKPIPTSGR----CSDLDTNTAKHV------------LCTGTVSDTD---SGFCMDLLIRLGEKVNFTYSVSLSEDGSYGSLRRVNGSDTKQWNGMVGEVIQGKADLIVAALTINNERAEWIEFSKPFKYQGLTILVKKNEQSNSLDSFLRPFQIHLWLLVLL-SVHIVAVILYLLDRFSPFGRFKLARKEKEETALNLSSAMWFSWGVLLNSGIGEGTPRSFSARVLGMVWAGFAMIIVASYTANLAAFLVLDRPKAVVSGIDDPNLRNP---SKQFIYATVANSSVDAYFRRQVELSSMYTFMEGYNVKTAKEGIEKVKNGELKAFIWDSPVLYYEASKD--CTLTTAGELFGRSGYGIGMPKGSPWSNAISLAILNFHESGVMEELETTWIDASKCNTEN--TSPATLGLQHMLGVF 801          
BLAST of Glutamate receptor ionotropic, NMDA 2B vs. Ensembl Nematostella
Match: EDO44842 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RUE9])

HSP 1 Score: 204.912 bits (520), Expect = 1.328e-58
Identity = 114/340 (33.53%), Postives = 187/340 (55.00%), Query Frame = 2
Query: 1748 CCTGMAIDILRELMKDLNFEVDLYEVPDRKWGAWSAEKGWNGLLESLINRKVDMAVSAFKITPNRSEQVDFTVPFQETGIAILVALHEGSISPTAFLKPYDWASWMVILIFSVHCCSTAMFIYEWLSPKGLDRGNVPPREHKFSLFRALWLIWAMLFGASVNVDSPRGMASRFLGCIWALFGLVFLASYTANLAAFMIAKEDHYDLKGLNDWRFQRPWNFKPEFRFATVPFSASEENIALNYPDIALYMRRYNKSSVEEGIRALKQK---EIDAFIYDSNVLEFRAAKDEGCKLRTVGNLYAVTGYGIAFPKGSKWYSKVNDLIMQYQKYDLLHRWKTFW 2758
            CC G+ ID+++ L +D+ F   +  +   + G++   K W GL+  ++    DMA+S+  IT  RS+ VDF+ PF  TG  ILVA   GS     FLKP+  ++W++I           + ++E  +P GL R        +F + +++WL+++  F   +N   PR ++SR +   W+   L+  A YTANLAAFM+ ++  + + G+ND R Q P       +F T+  ++ E+   +N+P +  +MR Y  +   EG+RA+K+     IDAFI++S  +E   A D  C L TVG L+  +G+  AFPKGS W   ++D I++YQ+ D+    +  W
Sbjct:    2 CCYGLCIDLIKLLSRDIGFIPVIETIQGGRAGSFKNGK-WTGLIGEVVAGNADMAMSSISITSQRSKFVDFSEPFIHTGSTILVAKRHGSFKGDGFLKPFKVSAWLLIFAVLYLVAVVVL-LFESHNP-GLQRQKHRNYRGEFDIHQSVWLMFSRFFSGILNAPIPRFVSSRVVLSSWSFATLMIDALYTANLAAFMVLQDQAHYIDGINDSRIQNP--LASVLKFTTIRDTSVEKYFKINFPHVYSFMRNYRFNHSSEGVRAVKEGYVIVIDAFIWESATMERYVANDTRCSLLTVGKLFDTSGFAAAFPKGSPWTRNISDFILKYQQTDVQGELRDKW 336          
BLAST of Glutamate receptor ionotropic, NMDA 2B vs. Ensembl Nematostella
Match: EDO34363 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SPJ5])

HSP 1 Score: 152.525 bits (384), Expect = 4.865e-40
Identity = 104/373 (27.88%), Postives = 172/373 (46.11%), Query Frame = 2
Query: 1748 CCTGMAIDILRELMKDLNFEVDLYEVPDRKWGAWSAEKG-WNGLLESLINRKVDMAVSAFKITPNRSEQVDFTVPFQETGIAILVALHE--GSISPTAFLKPYDWASWMVIL--IFSVHCCSTAMFIYEWLSPKGLDRGNVPPREHKFSLFRALWLIWAMLFGASVNVDSPRGMASRFLGCIWALFGLVFLASYTANLAAFMIAKEDHYDLKGLNDWRFQRPWNFKPEFRFATVPFSASEENIALNYPD----IALYMRRYNKSSVEEGIRALKQKEIDAFIYDSNVLEFRAAKDEGCKLRTVGNLYAVTGYGIAFPKGSKWYSKVNDLIMQYQKYDLLHRWKTFWLTGACKKTDKLANTNRTLGVRNFISAF 2839
            C +G  I++L  + + ++F  + Y + D K+G+     G WNG++  +I  + DMA++   IT +RS  +DF+ P+ E GI IL       GS+    F+ P     W VIL  I  V      +  +EW   KG     +P  + + SL  ++   W+           P   ++R +   +AL  L+   SYTA LAAF + ++    + G+ D + Q P    P+F+FAT+  S++E     +  +    I  +M+  N   VE+G+  L   E   +I D   LE   +    C LR +G  + ++GYGIA  K S W   +++ I++      L    + WL   C   D+   +   L + N    F
Sbjct:    1 CISGQMIELLELIREYVHFTYEFYLIRDHKYGSVDPVTGLWNGMVGDIITGEADMALATLTITASRSRVIDFSSPYGEVGIGILARTDTTLGSVVNMDFMIPLSSQLWTVILATILFVIIVLWVLGDWEWYL-KGRSH-FIPDYKRRVSLLESMTYSWSTFVHVQAGTGLPMSTSARLVALFFALAMLIVNTSYTAELAAFKVKEQFVPPISGIEDPKMQNP---PPDFKFATLRDSSTEAYFRFSKDEKLRRIYEHMKDNNVEMVEDGVAKLISGEFKLYIDDQPYLEHLVSSSGNCMLRMIGRPFGISGYGIALAKNSPWTRPISNAIIKLNDMKALENLWSKWLKRKCVTQDEFGKSPSGLSIENVNGLF 368          
BLAST of Glutamate receptor ionotropic, NMDA 2B vs. Ensembl Nematostella
Match: EDO48986 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RHH8])

HSP 1 Score: 144.05 bits (362), Expect = 2.100e-37
Identity = 100/356 (28.09%), Postives = 186/356 (52.25%), Query Frame = 2
Query: 1757 GMAIDILRELMKDLNFEVDLYEVPDRKWGAWS-AEKGWNGLLESLINRKVDMAVSAFKITPNRSEQVDFTVPFQETGIAILV---ALHEGSISPTAFLKPYDWASWMVILIFSVHCCSTAMFIYEWLSP----KGLDRGNVPPREHK-------FSLFRALWLIWAMLFGASVNVDSPRGMASRFLGCIWALFGLVFLASYTANLAAFMIAKEDHYDLKGLNDWRFQRPWNFKPE-FRFATVP------FSASEENIALNYPDIALYMRRYNKSSVEEGIRALKQKEIDAFIYDSNVLEFRAAKDEGCKLRTVGNLYAVTGYGIAFPKGSKWYSKVNDLIMQYQKYDLLHRWKTFW 2758
            G AID+L  + + LNFE +L    D ++G +    K WNG+++ L++ K D+ +  + I+  R+  +DFT P+  +GI +LV   +   G+I   ++L+P+    W+ +L  S+   S  +++ E L+P      +D G+     +K       F L  A+    A+ FG   +   P    +R     + +  L+F+++Y+ANLAAF+I ++ +  ++ + D +   P    PE F + TV       F A+ E+  +    +  +MR++N  + +EG+R +K      F+ +S+ L + +  D  C+L+ VG  +A++G  +A  KGS W++ +ND++ Q +  DL    + FW
Sbjct:    1 GFAIDVLELIKQALNFEPELRFSEDGQFGVYDEVNKTWNGIVKELLDDKGDITLDLY-ISARRATVLDFTEPYAPSGIRLLVKERSGKGGNIYWLSYLRPFTMNVWLTLL-GSMGIMSLFLWLVEKLAPCQTLTNIDEGDNSEETNKQPVAYGPFGLDNAICFTLALAFGRPADEAKPMLHGARLASVAFGVAMLMFVSTYSANLAAFLIVEDKYTTVENIYDPKIANP----PEGFTYGTVKGSYMADFFANAESTYMR--GMWYHMRKHNVETSKEGVRKVKSGNYCYFLAESSTLVYESLNDLDCELKVVGEPFAMSGASLAVKKGSPWFNALNDVLQQLKSKDLTDFIQKFW 348          
BLAST of Glutamate receptor ionotropic, NMDA 2B vs. Ensembl Nematostella
Match: EDO37551 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SFF8])

HSP 1 Score: 148.673 bits (374), Expect = 2.599e-36
Identity = 127/453 (28.04%), Postives = 207/453 (45.70%), Query Frame = 2
Query: 1418 FVTSWTKVGTWIMSSTLEEKRTKLQIDGVTWPGEVNKPPLGRPSKFKLRVSTLKEEPFVIFSVKQDKTCGNNALACSVLHDSLSISVDDFEKSKNRTKYLYMGNENYTDACCTGMAIDILRELMKDLNFEVDLYEVPDRKWGAWSAEKG-WNGLLESLINRKVDMAVSAFKITPNRSEQVDFTVPFQETGIAILVALHEGSISPT--AFLKPYDWASWMVILIFSVHCCSTAMFIYEWLSPKG---LDRGNVPPREHKFSLFRALWLIWAMLFGASVNVDSPRGMASRFLGCIWALFGLVFLASYTANLAAFMIAKEDHYDLKGLNDWRFQRPWNFKPEFRFATVPFSASEENIALNY-PDIALYMRRYNKS-----SVEEGIRALKQKEIDAFIYDSNVLEFRAAKDEGC---KLRTVG--NLYAVTGYGIAFPKGSKWYSKVNDLIMQYQK 2725
            F  SW  V +W+     + K T    + +T  G   K  LG P    LR + ++  P  + S        N  + C                     +Y   G E+YT  CC G+AID+L  +  +L FE  +Y V D  +GA +   G WNG++  LI  + D+++        RS+ VDF++ +   G+A+LV + E ++ P   AF  P+ W  W V +I +V+    A++I + LSP G   +++ +V  + H F L  ++W  W + F        P   +SR +    A+F L+ L SYTANL A +++ +    + G+ D +F        +     V  S  +    LN  P + +  RR   +     +  +G+R +K  E+D FI +   L++  AK +     +L+ VG    +A TGY  +F K S W  K  DL++   K
Sbjct:  370 FDKSWMTVSSWV-----DGKMTLAASEYLTPKG---KGALGMPV---LRAAVVEYPPLTMKSAYTPYIGCNQGIEC--------------------VEYRGPGREHYTKYCCYGLAIDVLNYVKTELEFEPFVYFVRDGNYGAKNLTSGEWNGVVRDLIRGEADISID-LMTNEARSDVVDFSLRWTHAGLALLVLVGEKNVEPIDFAFFDPFTWQLW-VGIIATVNVYLVALWIADRLSPYGYHQINKRSVDNKRH-FELDGSMWYCWGVCFDNQFVEQRPAAYSSRAMSVCLAMFALLCLTSYTANLTAHLVSDDTKPYVTGIRDKKFTAK---DSQISSGVVKSSYVDSYFELNQDPVMQMLFRRMRDNGHLVDNFTDGVRRVKSGELDIFISEILSLDYEVAKQKNTGYPRLQVVGASKPFADTGYSYSFRKNSTWKPKF-DLVVNRLK 784          
BLAST of Glutamate receptor ionotropic, NMDA 2B vs. Ensembl Medaka
Match: grin2ca (glutamate ionotropic receptor NMDA type subunit 2C [Source:NCBI gene;Acc:101159589])

HSP 1 Score: 335.109 bits (858), Expect = 1.946e-95
Identity = 193/558 (34.59%), Postives = 311/558 (55.73%), Query Frame = 2
Query: 1271 FMSTLSVDYNSNFYQFSVHNYLNSTSFLVMNTRSILDKSPLYEMEKEKHFVTSWTKVGTWIMSSTLEEKRTKLQIDGVTWP--GEVNKPPLGRPSKFK-LRVSTLKEEPFVIFSV--KQDKTCGNNALACSVLHDSLSISVDDFEKSKNRTKYLYMGNENYTDACCTGMAIDILRELMKDLNFEVDLYEVPDRKWGAWSAEKGWNGLLESLINRKVDMAVSAFKITPNRSEQVDFTVPFQETGIAILVALHEGSISPTAFLKPYDWASWMVILIFSVHCCSTAMFIYEWLSPKGLDRGNVP---PREHKFSLFRALWLIWAMLFGASVNVDSPRGMASRFLGCIWALFGLVFLASYTANLAAFMIAKEDHYDLKGLNDWRFQRPWNFKPEFRFATVPFSASEENIALNYPDIALYMRRYNKSSVEEGIRALKQKEIDAFIYDSNVLEFRAAKDEGCKLRTVGN--LYAVTGYGIAFPKGSKWYSKVNDLIMQYQKYDLLHRWKTFWLTGACKKTDKLANTNRTLGVRNFISAFXXXXXXXXXXXXXXXCEHLFFRYLR 2914
            F   L+V +  N + F+ + YL + + +++             +++E+     W KVGT+ +          LQ+    WP  G   +P     S ++ L V+TL+E PFVI         TC +N + C               +  N+T+ +    E YT  CC G  IDIL++L + + F  DLY V + K G       WNG++  +  ++ DMA+ +  I   RSE +DF+VPF ETGI+++VA   G++SP+AFL+PY  A W+++ +  +   +  +F++E+ SP G +R  V    P    F++ +++WL+W ++F  SV +++P+G  S+ +  +WA F ++FLASYTANLAAFMI ++    + GL+D +FQ+P    P FRF TVP  ++E NI  NYP++  +M +YN+  VE+ + +LK  ++DAFIYD+ VL + A KDEGCKL T+G+  ++A TGYGIA  K S W   ++  ++Q+       + +T WLTG C+   K   +++ L + N    F +LL  + +S L+   EHL +  LR
Sbjct:  341 FRHMLNVTWEHNDFSFNSNGYLVNPAMIIIT------------LDRERQ----WDKVGTYEVG--------ILQMRYPVWPRFGSYLEPV----SDYRHLTVATLEERPFVIVEAVDPATGTCVSNTVPC--------------RRQSNKTETIVGHTEPYTKLCCKGFCIDILKKLARTIKFSYDLYLVTNGKHGKL-VRGIWNGMIGEVFYKRADMAIGSLTINEERSEIIDFSVPFVETGISVMVARSNGTVSPSAFLEPYSPAVWVMMFVMCLTVVAITVFVFEYCSPVGYNRSLVTAKDPGGPTFTIGKSVWLLWGIVFNNSVPIENPKGTTSKIMVLVWAFFAVIFLASYTANLAAFMIQEQYIDTVSGLSDKKFQKPQEQYPPFRFGTVPNGSTERNIRSNYPEMHAHMVKYNQKGVEDALNSLKTGKLDAFIYDAAVLNYMAGKDEGCKLVTIGSGKVFATTGYGIALQKDSSWKRPIDLALLQFLADGDTQKLQTVWLTGICRNEKKEVMSSK-LDIDNMAGVFYMLLVAMGLSLLVFAWEHLLYWKLR 854          
BLAST of Glutamate receptor ionotropic, NMDA 2B vs. Ensembl Medaka
Match: ENSORLT00000013760.2 (glutamate receptor ionotropic, NMDA 2C [Source:NCBI gene;Acc:101166504])

HSP 1 Score: 329.717 bits (844), Expect = 1.224e-93
Identity = 213/661 (32.22%), Postives = 343/661 (51.89%), Query Frame = 2
Query: 1271 FMSTLSVDYNSNFYQFSVHNYLNSTSFLVMNTRSILDKSPLYEMEKEKHFVTSWTKVGTWIMSSTLEEKRTKLQIDGVTWPGEVNKPPLGRPSKF--------KLRVSTLKEEPFVIFSV--KQDKTCGNNALACSVLHDSLSISVDDFEKSKNRTKYLYMGNENYTDACCTGMAIDILRELMKDLNFEVDLYEVPDRKWGAWSAEKGWNGLLESLIN-RKVDMAVSAFKITPNRSEQVDFTVPFQETGIAILVALHEGSISPTAFLKPYDWASWMVILIFSVHCCSTAMFIYEWLSPKGLDRGNV---PPREHKFSLFRALWLIWAMLFGASVNVDSPRGMASRFLGCIWALFGLVFLASYTANLAAFMIAKEDHYDLKGLNDWRFQRPWNFKPEFRFATVPFSASEENIALNYPDIALYMRRYNKSSVEEGIRALKQKEIDAFIYDSNVLEFRAAKDEGCKLRTVGN--LYAVTGYGIAFPKGSKWYSKVNDLIMQYQKYDLLHRWKTFWLTGACKKTDKLANTNRTLGVRNFISAFXXXXXXXXXXXXXXXCEHLFFRYLRPRMSNLDQYGCCGLISLSMGQLLSFEQTVN-------QTVDFVKNYKCHNPLCENQIWRLRKELEMSKEIIRKLETSFEGLNSSLRSMSSFPKFVNQ 3184
            F   L+V +      F+   +L++ S +++             +++E+     W KVGT+         R  LQ+    WP         R   F         L V+TL+E PFV+         TC  N + C               +  N T+ ++   E+YT  CC G  IDIL++L +++ F  DLY V + K G       WNG++  + N ++ DMA+ +  I   RSE +DF+VPF ETGI+++VA   G++SP+AFL+PY  A W+++ +  +   +  +F++E+ SP G +R  V    P    F++ +++WL+W ++F  SV +++P+G  S+ +  +WA F ++FLASYTANLAAFMI ++    + GL+D +FQ+P    P FRF TVP  ++E NI  NYPD+  +M RYN+  VEE +++LK  ++DAFIYD+ VL + A KDEGCKL T+G+  ++A TGYGIA  K S+W   ++  ++Q+       R +T WL+G C+  +K    +  L + N    F +LL  + +S ++   EHL +  LR  +   D+     L+++S G    F+   +          D   NY   N L   ++ R  K+L  +  +   L+ + + +    R   S P  V Q
Sbjct:  339 FRHMLNVTWERKDLSFNSQGFLSNPSMVIIT------------LDRERQ----WDKVGTF--------ARGILQVRYPIWP---------RYGSFLEHVSDDRHLTVATLEEHPFVMVENVDPGTGTCVRNTVPC--------------RRQSNYTESVFGPTESYTKLCCKGFCIDILKKLSRNIKFSFDLYLVTNGKHGKL-VHGVWNGMIGEVRNAQRADMAIGSLTINEERSEIIDFSVPFVETGISVMVARSNGTVSPSAFLEPYSPAVWVMMFVMCLTVVAVTVFVFEYFSPVGYNRSLVSAKAPGGPTFTIGKSVWLLWGIVFNNSVPIENPKGTTSKIMVLVWAFFAVIFLASYTANLAAFMIQEQYIDTVSGLSDKKFQKPQEHYPPFRFGTVPNGSTERNIRSNYPDMHTHMMRYNQKGVEEALQSLKTGKLDAFIYDAAVLNYMAGKDEGCKLVTIGSGKVFATTGYGIALVKDSRWKRPIDLALLQFLGDGDTERLETVWLSGICQN-EKNEVMSSKLDIDNMAGVFYMLLVAMGLSMVVFAWEHLLYWKLRHSLHKSDKVDF--LLAISRGIYSCFKGVEDPGRSSGLAKPDLTSNYAQANML---KMLRTAKDLVSTANVESSLDNATKTIEHLTRHGGSLPVRVPQ 945          
BLAST of Glutamate receptor ionotropic, NMDA 2B vs. Ensembl Medaka
Match: ENSORLT00000011525.2 (glutamate receptor ionotropic, NMDA 2A [Source:NCBI gene;Acc:101164378])

HSP 1 Score: 320.857 bits (821), Expect = 3.696e-90
Identity = 173/459 (37.69%), Postives = 266/459 (57.95%), Query Frame = 2
Query: 1559 LRVSTLKEEPFVIFSVKQ--DKTCGNNALACSVLHDSLSISVDDFEKSKNRTKYLYMGNENYTDACCTGMAIDILRELMKDLNFEVDLYEVPDRKWGAWSAEKGWNGLLESLINRKVDMAVSAFKITPNRSEQVDFTVPFQETGIAILVALHEGSISPTAFLKPYDWASWMVILIFSVHCCSTAMFIYEWLSPKGLDRG---NVPPREHKFSLFRALWLIWAMLFGASVNVDSPRGMASRFLGCIWALFGLVFLASYTANLAAFMIAKEDHYDLKGLNDWRFQRPWNFKPEFRFATVPFSASEENIALNYPDIALYMRRYNKSSVEEGIRALKQKEIDAFIYDSNVLEFRAAKDEGCKLRTVGN--LYAVTGYGIAFPKGSKWYSKVNDLIMQYQKYDLLHRWKTFWLTGACKKTDKLANTNRTLGVRNFISAFXXXXXXXXXXXXXXXCEHLFFRYLR 2914
            L + TL+E+PFVI         TC  N++ C                 +   K        Y   CC G  IDIL+++ +++ F  DLY V + K G       WNG++  ++ +K  MAV +  I   RSE +DF+VPF ETGI+++V+   G++SP+AFL+P+  + W+++ +  +   + A+F++E++SP G +R       P    F++ +A+WL+W ++F  SV V +PRG  S+F+  +WA F ++FLASYTANLAAFMI +E    + GL+D +FQ P+++ P FRF TVP  ++E NI  NYPD+  YM +Y+++ V + + +LK  ++DAFIYD+ VL + A +D+GCKL T+G+  ++A TGYGIA  KGS W   V+  I+       +   +  WLTG C   +K    +  L V N    F +L T + +S L  I EHLF+  LR
Sbjct:  475 LSIVTLEEKPFVIVDNVDILTGTCMRNSVPC-----------------RKHVKLNSTSGGAYIKQCCKGFCIDILKKIARNVKFTYDLYLVTNGKHGK-KINNMWNGMVGEVVYKKAVMAVGSLTINEERSEVIDFSVPFVETGISVMVSRSNGTVSPSAFLEPFSASVWVMMFVMLLIVTAIAVFLFEFISPLGFNRNLAQGKDPHGPSFTIGKAIWLLWGLVFNNSVPVQNPRGTTSKFIVSVWAFFAVIFLASYTANLAAFMIQEEFVDQVTGLSDKKFQSPYSYSPPFRFGTVPNGSTERNIRKNYPDMHQYMTKYHQTGVTDALVSLKTGKLDAFIYDAAVLNYMAGRDDGCKLVTIGSGYIFATTGYGIALQKGSYWKRHVDLAILSIIGDGEMEELEAQWLTGICHN-EKNEVMSSQLDVDNMAGVFYMLATAMGLSILTFISEHLFYWRLR 914          
BLAST of Glutamate receptor ionotropic, NMDA 2B vs. Ensembl Medaka
Match: ENSORLT00000040618.1 (glutamate receptor ionotropic, NMDA 2A [Source:NCBI gene;Acc:101164378])

HSP 1 Score: 320.857 bits (821), Expect = 4.485e-90
Identity = 173/459 (37.69%), Postives = 266/459 (57.95%), Query Frame = 2
Query: 1559 LRVSTLKEEPFVIFSVKQ--DKTCGNNALACSVLHDSLSISVDDFEKSKNRTKYLYMGNENYTDACCTGMAIDILRELMKDLNFEVDLYEVPDRKWGAWSAEKGWNGLLESLINRKVDMAVSAFKITPNRSEQVDFTVPFQETGIAILVALHEGSISPTAFLKPYDWASWMVILIFSVHCCSTAMFIYEWLSPKGLDRG---NVPPREHKFSLFRALWLIWAMLFGASVNVDSPRGMASRFLGCIWALFGLVFLASYTANLAAFMIAKEDHYDLKGLNDWRFQRPWNFKPEFRFATVPFSASEENIALNYPDIALYMRRYNKSSVEEGIRALKQKEIDAFIYDSNVLEFRAAKDEGCKLRTVGN--LYAVTGYGIAFPKGSKWYSKVNDLIMQYQKYDLLHRWKTFWLTGACKKTDKLANTNRTLGVRNFISAFXXXXXXXXXXXXXXXCEHLFFRYLR 2914
            L + TL+E+PFVI         TC  N++ C                 +   K        Y   CC G  IDIL+++ +++ F  DLY V + K G       WNG++  ++ +K  MAV +  I   RSE +DF+VPF ETGI+++V+   G++SP+AFL+P+  + W+++ +  +   + A+F++E++SP G +R       P    F++ +A+WL+W ++F  SV V +PRG  S+F+  +WA F ++FLASYTANLAAFMI +E    + GL+D +FQ P+++ P FRF TVP  ++E NI  NYPD+  YM +Y+++ V + + +LK  ++DAFIYD+ VL + A +D+GCKL T+G+  ++A TGYGIA  KGS W   V+  I+       +   +  WLTG C   +K    +  L V N    F +L T + +S L  I EHLF+  LR
Sbjct:  504 LSIVTLEEKPFVIVDNVDILTGTCMRNSVPC-----------------RKHVKLNSTSGGAYIKQCCKGFCIDILKKIARNVKFTYDLYLVTNGKHGK-KINNMWNGMVGEVVYKKAVMAVGSLTINEERSEVIDFSVPFVETGISVMVSRSNGTVSPSAFLEPFSASVWVMMFVMLLIVTAIAVFLFEFISPLGFNRNLAQGKDPHGPSFTIGKAIWLLWGLVFNNSVPVQNPRGTTSKFIVSVWAFFAVIFLASYTANLAAFMIQEEFVDQVTGLSDKKFQSPYSYSPPFRFGTVPNGSTERNIRKNYPDMHQYMTKYHQTGVTDALVSLKTGKLDAFIYDAAVLNYMAGRDDGCKLVTIGSGYIFATTGYGIALQKGSYWKRHVDLAILSIIGDGEMEELEAQWLTGICHN-EKNEVMSSQLDVDNMAGVFYMLATAMGLSILTFISEHLFYWRLR 943          
BLAST of Glutamate receptor ionotropic, NMDA 2B vs. Ensembl Medaka
Match: grin2aa (glutamate ionotropic receptor NMDA type subunit 2A [Source:NCBI gene;Acc:101161811])

HSP 1 Score: 315.079 bits (806), Expect = 3.032e-88
Identity = 179/488 (36.68%), Postives = 275/488 (56.35%), Query Frame = 2
Query: 1559 LRVSTLKEEPFVIFS--VKQDKTCGNNALACSVLHDSLSISVDDFEKSKNRTKYLYMGNENYTDACCTGMAIDILRELMKDLNFEVDLYEVPDRKWGAWSAEKGWNGLLESLINRKVDMAVSAFKITPNRSEQVDFTVPFQETGIAILVALHEGSISPTAFLKPYDWASWMVILIFSVHCCSTAMFIYEWLSPKGLDRG---NVPPREHKFSLFRALWLIWAMLFGASVNVDSPRGMASRFLGCIWALFGLVFLASYTANLAAFMIAKEDHYDLKGLNDWRFQRPWNFKPEFRFATVPFSASEENIALNYPDIALYMRRYNKSSVEEGIRALKQKEIDAFIYDSNVLEFRAAKDEGCKLRTVGN--LYAVTGYGIAFPKGSKWYSKVNDLIMQYQKYDLLHRWKTFWLTGACKKTDKLANTNRTLGVRNFISAFXXXXXXXXXXXXXXXCEHLFFRYLRPRMSNLDQYGCCGLISLSMGQLLSFEQTV 3001
            L + TL+E+PFVI     +   TC  N++ C              +  K+ T         Y   CC G  IDIL+++ K + F  DLY V + K G       WNG++  ++ +K  MAV +  I   RSE +DF+VPF ETGI+++V+   G++SP+AFL+P+  + W+++ +  +   + A+F++E++SP G +R       P    F++ +A+WL+W ++F  SV V +P+G  S+F+  +WA F ++FLASYTANLAAFMI +E    + GL+D +FQ P  + P FRF TVP  ++E NI  NYP +  YM +Y+++ V + + +LK  ++DAFIYD+ VL + A +DEGCKL T+G+  ++A TGYGIA  KGS W  +V+  I+       +   +  WLTG C   +K    +  L V N    F +L T + +S +  I EHLF+  LR        Y   G+ S   G L S  + +
Sbjct:  425 LSIVTLEEKPFVIVEDVERLTGTCMRNSVPCR-------------KHIKDNTTE---AGGTYIKKCCKGFCIDILKKIAKYVKFTYDLYLVTNGKHGK-KINNVWNGMVGEVVYKKAVMAVGSLTINEERSEVIDFSVPFVETGISVMVSRSNGTVSPSAFLEPFSASVWVMMFVMLLLVTAMAVFMFEYISPLGFNRNLAQGKDPHGPSFTMGKAVWLLWGLVFNNSVPVQNPKGTTSKFIVSVWAFFAVIFLASYTANLAAFMIQEEFVDQVTGLSDNKFQNPHAYSPPFRFGTVPNGSTERNIRKNYPAMHQYMVKYHQTGVVDALVSLKTGKLDAFIYDAAVLNYMAGRDEGCKLVTIGSGYIFATTGYGIALQKGSYWKRQVDLAILAIIGDGEMEELEAQWLTGIC-HNEKNEVMSSQLDVDNMAGVFYMLATAMGLSLITFISEHLFYWRLR--------YCFTGVCSGKPGLLFSISRGI 886          
BLAST of Glutamate receptor ionotropic, NMDA 2B vs. Planmine SMEST
Match: SMESG000048391.1 (SMESG000048391.1)

HSP 1 Score: 924.08 bits (2387), Expect = 0.000e+0
Identity = 476/477 (99.79%), Postives = 476/477 (99.79%), Query Frame = 2
Query: 2063 MVILIFSVHCCSTAMFIYEWLSPKGLDRGNVPPREHKFSLFRALWLIWAMLFGASVNVDSPRGMASRFLGCIWALFGLVFLASYTANLAAFMIAKEDHYDLKGLNDWRFQRPWNFKPEFRFATVPFSASEENIALNYPDIALYMRRYNKSSVEEGIRALKQKEIDAFIYDSNVLEFRAAKDEGCKLRTVGNLYAVTGYGIAFPKGSKWYSKVNDLIMQYQKYDLLHRWKTFWLTGACKKTDKLANTNRTLGVRNFISAFXXXXXXXXXXXXXXXCEHLFFRYLRPRMSNLDQYGCCGLISLSMGQLLSFEQTVNQTVDFVKNYKCHNPLCENQIWRLRKELEMSKEIIRKLETSFEGLNSSLRSMSSFPKFVNQAEADNKNSASLLKSKEYHSFNNPPVDNSCQIQDADDKNKNSNSSFQLAHEXXXXXXXXXXXXXXXPEKLTYTCFVENSLLSQTQLHSNSRKCRNFIIQQESSL 3493
            MVILIFSVHCCSTAMFIYEWLSPKGLDRGNVPPREHKFSLFRALWLIWAMLFGASVNVDSPRGMASRFLGCIWALFGLVFLASYTANLAAFMIAKEDHYDLKGLNDWRFQRPWNFKPEFRFATVPFSASEENIALNYPDIALYMRRYNKSSVEEGIRALKQKEIDAFIYDSNVLEFRAAKDEGCKLRTVGNLYAVTGYGIAFPKGSKWYSKVNDLIMQYQKYDLLHRWKTFWLTGACKKTDKLANTNRTLGVRNFISAFILLLTGLIISTLLLICEHLFFRYLRPRMSNLDQYGCCGLISLSMGQLLSFEQTVNQTVDFVKNYKCHNPLCENQIWRLRKELEMSKEIIRKLETSFEGLNSSLRSMSSFPKFVNQAEADNKNSASLLKSKEYHSFNNPPVDNSCQIQDADDKNKNSNSSFQ AHEISRRKSSSFISINSIPEKLTYTCFVENSLLSQTQLHSNSRKCRNFIIQQESSL
Sbjct:    1 MVILIFSVHCCSTAMFIYEWLSPKGLDRGNVPPREHKFSLFRALWLIWAMLFGASVNVDSPRGMASRFLGCIWALFGLVFLASYTANLAAFMIAKEDHYDLKGLNDWRFQRPWNFKPEFRFATVPFSASEENIALNYPDIALYMRRYNKSSVEEGIRALKQKEIDAFIYDSNVLEFRAAKDEGCKLRTVGNLYAVTGYGIAFPKGSKWYSKVNDLIMQYQKYDLLHRWKTFWLTGACKKTDKLANTNRTLGVRNFISAFILLLTGLIISTLLLICEHLFFRYLRPRMSNLDQYGCCGLISLSMGQLLSFEQTVNQTVDFVKNYKCHNPLCENQIWRLRKELEMSKEIIRKLETSFEGLNSSLRSMSSFPKFVNQAEADNKNSASLLKSKEYHSFNNPPVDNSCQIQDADDKNKNSNSSFQSAHEISRRKSSSFISINSIPEKLTYTCFVENSLLSQTQLHSNSRKCRNFIIQQESSL 477          
BLAST of Glutamate receptor ionotropic, NMDA 2B vs. Planmine SMEST
Match: SMESG000048395.1 (SMESG000048395.1)

HSP 1 Score: 842.032 bits (2174), Expect = 0.000e+0
Identity = 425/425 (100.00%), Postives = 425/425 (100.00%), Query Frame = 2
Query:  764 MSVLKSEERLSSYKKSLEHILAADHRIILFYGMKYDLIIMHKIALKDPNLSKIFGAEFVWILCPEAITPTMSVMNKKEKFSPSLELSEDMPPLPGVFGFAYAPTTSMLKDNLNIATSFWKTSVEXXXXXXXXXXXXXXXEILERMIPKLNCQSKVDRNDAWTFGKYIYKFMSTLSVDYNSNFYQFSVHNYLNSTSFLVMNTRSILDKSPLYEMEKEKHFVTSWTKVGTWIMSSTLEEKRTKLQIDGVTWPGEVNKPPLGRPSKFKLRVSTLKEEPFVIFSVKQDKTCGNNALACSVLHDSLSISVDDFEKSKNRTKYLYMGNENYTDACCTGMAIDILRELMKDLNFEVDLYEVPDRKWGAWSAEKGWNGLLESLINRKVDMAVSAFKITPNRSEQVDFTVPFQETGIAILVALHEGSISPTAFL 2038
            MSVLKSEERLSSYKKSLEHILAADHRIILFYGMKYDLIIMHKIALKDPNLSKIFGAEFVWILCPEAITPTMSVMNKKEKFSPSLELSEDMPPLPGVFGFAYAPTTSMLKDNLNIATSFWKTSVENLINNLTIRNNISRTEILERMIPKLNCQSKVDRNDAWTFGKYIYKFMSTLSVDYNSNFYQFSVHNYLNSTSFLVMNTRSILDKSPLYEMEKEKHFVTSWTKVGTWIMSSTLEEKRTKLQIDGVTWPGEVNKPPLGRPSKFKLRVSTLKEEPFVIFSVKQDKTCGNNALACSVLHDSLSISVDDFEKSKNRTKYLYMGNENYTDACCTGMAIDILRELMKDLNFEVDLYEVPDRKWGAWSAEKGWNGLLESLINRKVDMAVSAFKITPNRSEQVDFTVPFQETGIAILVALHEGSISPTAFL
Sbjct:    1 MSVLKSEERLSSYKKSLEHILAADHRIILFYGMKYDLIIMHKIALKDPNLSKIFGAEFVWILCPEAITPTMSVMNKKEKFSPSLELSEDMPPLPGVFGFAYAPTTSMLKDNLNIATSFWKTSVENLINNLTIRNNISRTEILERMIPKLNCQSKVDRNDAWTFGKYIYKFMSTLSVDYNSNFYQFSVHNYLNSTSFLVMNTRSILDKSPLYEMEKEKHFVTSWTKVGTWIMSSTLEEKRTKLQIDGVTWPGEVNKPPLGRPSKFKLRVSTLKEEPFVIFSVKQDKTCGNNALACSVLHDSLSISVDDFEKSKNRTKYLYMGNENYTDACCTGMAIDILRELMKDLNFEVDLYEVPDRKWGAWSAEKGWNGLLESLINRKVDMAVSAFKITPNRSEQVDFTVPFQETGIAILVALHEGSISPTAFL 425          
BLAST of Glutamate receptor ionotropic, NMDA 2B vs. Planmine SMEST
Match: SMESG000021416.1 (SMESG000021416.1)

HSP 1 Score: 758.829 bits (1958), Expect = 0.000e+0
Identity = 390/789 (49.43%), Postives = 530/789 (67.17%), Query Frame = 2
Query:  812 LEHILAADHRIILFYGMKYDLIIM-----HKIALKDPNLSKIFGAEFVWILCPEAITPTMSVMNKKEKFSPSL-------ELSEDMPPLPGVFGFAYAPTTSMLKDNLNIATSFWKTSVEXXXXXXXXXXXXXXXEILERMIPKLNCQSKVDRNDAWTFGKYIYKFMSTLSVDYNSNFYQFSVHNYLNSTSFLVMNTRSILDKSPLYEMEKEKHFVTSWTKVGTWIMSSTLEEKRTKLQIDGVTWPGEVNKPPLGRPSKFKLRVSTLKEEPFVIFSVKQDKTCGNNALACSVLHDSLSISVDDFEKSKNRTKYLYMG-----NENYTDACCTGMAIDILRELMKDLNFEVDLYEVPDRKWGAWSAEKGWNGLLESLINRKVDMAVSAFKITPNRSEQVDFTVPFQETGIAILVALHEGSISPTAFLKPYDWASWMVILIFSVHCCSTAMFIYEWLSPKGLDRGNVPPREHKFSLFRALWLIWAMLFGASVNVDSPRGMASRFLGCIWALFGLVFLASYTANLAAFMIAKEDHYDLKGLNDWRFQRPWNFKPEFRFATVPFSASEENIALNYPDIALYMRRYNKSSVEEGIRALKQKEIDAFIYDSNVLEFRAAKDEGCKLRTVGNLYAVTGYGIAFPKGSKWYSKVNDLIMQYQKYDLLHRWKTFWLTGACKKTDKLANTNRTLGVRNFISAFXXXXXXXXXXXXXXXCEHLFFRYLRPRMSNLDQYGCCGLISLSMGQLLSFEQTVNQTVDFVKNYKCHNPLCENQIWRLRKELEMSKEIIRKLETSF 3127
            L+ +   + R+ILF+G +Y+L+++          K   L+++FG+ ++W+  P  +TP  + M + E  +P L       ++ +    +PG+F F         K    +A   W  S+  L   L  R+  + + I++++ P   C++K   N     G  +Y+ M ++++  N  +  F  +  +N+T  L+ N++  +                 W KVGTW MSS   +K++ L+IDGVTWPG   KPP GRP KF+LRV+T+KE PFV F   +   C  N+L C V   +  +S    E + N T Y   G     +  Y  ACC+G+ +D+L ELMKDL FEVDL+EVPD KWG W+ + GWNGL++ L +   DMAV++FKITPNRSEQ+DF+VPF +TGIAI+VAL EG ISPTAFL+PYD+ SW VIL+FSVH C  A+FIYEWLSP GLDRGN    EHKFS FR+LWLIW+MLFGA+VN D+PRG ASRFL  IWALF LVFLASYTANLAAFMIAK+D YDL G+ D     P  FKP F FATVP  A+EENI +N+P +  YM+++N+SSVEEGI+ALK  EI+AFIYDSNVLE+RA KDE CKL+TVGNL+A+TGYG+ FPK SKW + +ND I+ Y+    + RWK +WLTGACKK  +L +TN+ LGV+NFISAFILLL G+I+ +LLL+ EH F++YLRP ++N+D+YGCCGL+S+SMGQ+L+FEQ+VNQTVD VK++KC N +CE++  + R E +  K+ +  LE + 
Sbjct:  250 LKELHKNNDRVILFHGTQYELMLLISAVKEYAVDKSSYLNEMFGSNYIWLCSPALVTPVKNEM-RSESINPDLFVIKGSWKVGKVDLQIPGMFVFVTFNNFESYKSKAIMARELWARSLSKLTEILKERHPNNISAIVDKLRPSDLCENK---NPKLKMGPQLYQIMKSMTLKINDEYIGFLNNGAINTTELLIFNSQKKISG-------------LGWHKVGTWSMSSKWGKKKSNLRIDGVTWPGNEIKPPRGRPDKFRLRVTTIKEVPFVQFRESETGNCDGNSLKCWVRDLNRQLS----ESNVNETFYAIFGVNVTSDHPYVPACCSGLTMDMLSELMKDLEFEVDLFEVPDGKWGGWTFD-GWNGLVKVLKDHSADMAVTSFKITPNRSEQIDFSVPFLQTGIAIIVALREGGISPTAFLEPYDYQSWCVILVFSVHACGAALFIYEWLSPHGLDRGNQVTAEHKFSFFRSLWLIWSMLFGAAVNADNPRGTASRFLANIWALFALVFLASYTANLAAFMIAKDDFYDLTGIKDAHLMNPLGFKPPFTFATVPSGATEENIKINFPTMYEYMKKFNRSSVEEGIKALKTGEINAFIYDSNVLEYRATKDENCKLKTVGNLFAMTGYGVGFPKSSKWLNLINDRILNYESNGKMQRWKQYWLTGACKKDRRLDSTNKRLGVKNFISAFILLLGGIILCSLLLLLEHTFYKYLRPHLTNIDKYGCCGLVSISMGQILNFEQSVNQTVDMVKHHKCSNIICESKWLKARNEADRLKKRVEMLEDAL 1016          

HSP 2 Score: 73.1738 bits (178), Expect = 1.025e-12
Identity = 42/139 (30.22%), Postives = 76/139 (54.68%), Query Frame = 3
Query:  303 PQAIHNAICKILQPKRRKKXXXXXXXXXXXXDNLDAKSSKVIEYFVNLISNLGVPTITWLPSQLGQILFEEGPMALRLEPSNKHLAEAMFDFVQTYNWXXXXXXXXXXXXXXXXFVQMLKEVITERESSSKDDYFKLKI 719
            P A+ + ICK L+  +    + V     +  +  +    + I++ +++ S++G+PT TW P + GQ   ++  +A+RLEP+N H+ +AM DF+Q YNW  V  +VS  +    NF++ L+    ER   + +  F+  I
Sbjct:   82 PTALKSEICKELRQNQVNTFMLVNDDGELEKETFN----RGIDFIIHMASSMGIPTFTWFPDKAGQYKLDKSSLAIRLEPANWHIIQAMVDFMQAYNWTQVATIVSKKIPNHQNFIKELQLAQKERGLMNNEKLFRFII 216          
BLAST of Glutamate receptor ionotropic, NMDA 2B vs. Planmine SMEST
Match: SMESG000021416.1 (SMESG000021416.1)

HSP 1 Score: 758.829 bits (1958), Expect = 0.000e+0
Identity = 390/789 (49.43%), Postives = 530/789 (67.17%), Query Frame = 2
Query:  812 LEHILAADHRIILFYGMKYDLIIM-----HKIALKDPNLSKIFGAEFVWILCPEAITPTMSVMNKKEKFSPSL-------ELSEDMPPLPGVFGFAYAPTTSMLKDNLNIATSFWKTSVEXXXXXXXXXXXXXXXEILERMIPKLNCQSKVDRNDAWTFGKYIYKFMSTLSVDYNSNFYQFSVHNYLNSTSFLVMNTRSILDKSPLYEMEKEKHFVTSWTKVGTWIMSSTLEEKRTKLQIDGVTWPGEVNKPPLGRPSKFKLRVSTLKEEPFVIFSVKQDKTCGNNALACSVLHDSLSISVDDFEKSKNRTKYLYMG-----NENYTDACCTGMAIDILRELMKDLNFEVDLYEVPDRKWGAWSAEKGWNGLLESLINRKVDMAVSAFKITPNRSEQVDFTVPFQETGIAILVALHEGSISPTAFLKPYDWASWMVILIFSVHCCSTAMFIYEWLSPKGLDRGNVPPREHKFSLFRALWLIWAMLFGASVNVDSPRGMASRFLGCIWALFGLVFLASYTANLAAFMIAKEDHYDLKGLNDWRFQRPWNFKPEFRFATVPFSASEENIALNYPDIALYMRRYNKSSVEEGIRALKQKEIDAFIYDSNVLEFRAAKDEGCKLRTVGNLYAVTGYGIAFPKGSKWYSKVNDLIMQYQKYDLLHRWKTFWLTGACKKTDKLANTNRTLGVRNFISAFXXXXXXXXXXXXXXXCEHLFFRYLRPRMSNLDQYGCCGLISLSMGQLLSFEQTVNQTVDFVKNYKCHNPLCENQIWRLRKELEMSKEIIRKLETSF 3127
            L+ +   + R+ILF+G +Y+L+++          K   L+++FG+ ++W+  P  +TP  + M + E  +P L       ++ +    +PG+F F         K    +A   W  S+  L   L  R+  + + I++++ P   C++K   N     G  +Y+ M ++++  N  +  F  +  +N+T  L+ N++  +                 W KVGTW MSS   +K++ L+IDGVTWPG   KPP GRP KF+LRV+T+KE PFV F   +   C  N+L C V   +  +S    E + N T Y   G     +  Y  ACC+G+ +D+L ELMKDL FEVDL+EVPD KWG W+ + GWNGL++ L +   DMAV++FKITPNRSEQ+DF+VPF +TGIAI+VAL EG ISPTAFL+PYD+ SW VIL+FSVH C  A+FIYEWLSP GLDRGN    EHKFS FR+LWLIW+MLFGA+VN D+PRG ASRFL  IWALF LVFLASYTANLAAFMIAK+D YDL G+ D     P  FKP F FATVP  A+EENI +N+P +  YM+++N+SSVEEGI+ALK  EI+AFIYDSNVLE+RA KDE CKL+TVGNL+A+TGYG+ FPK SKW + +ND I+ Y+    + RWK +WLTGACKK  +L +TN+ LGV+NFISAFILLL G+I+ +LLL+ EH F++YLRP ++N+D+YGCCGL+S+SMGQ+L+FEQ+VNQTVD VK++KC N +CE++  + R E +  K+ +  LE + 
Sbjct:  242 LKELHKNNDRVILFHGTQYELMLLISAVKEYAVDKSSYLNEMFGSNYIWLCSPALVTPVKNEM-RSESINPDLFVIKGSWKVGKVDLQIPGMFVFVTFNNFESYKSKAIMARELWARSLSKLTEILKERHPNNISAIVDKLRPSDLCENK---NPKLKMGPQLYQIMKSMTLKINDEYIGFLNNGAINTTELLIFNSQKKISG-------------LGWHKVGTWSMSSKWGKKKSNLRIDGVTWPGNEIKPPRGRPDKFRLRVTTIKEVPFVQFRESETGNCDGNSLKCWVRDLNRQLS----ESNVNETFYAIFGVNVTSDHPYVPACCSGLTMDMLSELMKDLEFEVDLFEVPDGKWGGWTFD-GWNGLVKVLKDHSADMAVTSFKITPNRSEQIDFSVPFLQTGIAIIVALREGGISPTAFLEPYDYQSWCVILVFSVHACGAALFIYEWLSPHGLDRGNQVTAEHKFSFFRSLWLIWSMLFGAAVNADNPRGTASRFLANIWALFALVFLASYTANLAAFMIAKDDFYDLTGIKDAHLMNPLGFKPPFTFATVPSGATEENIKINFPTMYEYMKKFNRSSVEEGIKALKTGEINAFIYDSNVLEYRATKDENCKLKTVGNLFAMTGYGVGFPKSSKWLNLINDRILNYESNGKMQRWKQYWLTGACKKDRRLDSTNKRLGVKNFISAFILLLGGIILCSLLLLLEHTFYKYLRPHLTNIDKYGCCGLVSISMGQILNFEQSVNQTVDMVKHHKCSNIICESKWLKARNEADRLKKRVEMLEDAL 1008          

HSP 2 Score: 73.1738 bits (178), Expect = 1.040e-12
Identity = 42/139 (30.22%), Postives = 76/139 (54.68%), Query Frame = 3
Query:  303 PQAIHNAICKILQPKRRKKXXXXXXXXXXXXDNLDAKSSKVIEYFVNLISNLGVPTITWLPSQLGQILFEEGPMALRLEPSNKHLAEAMFDFVQTYNWXXXXXXXXXXXXXXXXFVQMLKEVITERESSSKDDYFKLKI 719
            P A+ + ICK L+  +    + V     +  +  +    + I++ +++ S++G+PT TW P + GQ   ++  +A+RLEP+N H+ +AM DF+Q YNW  V  +VS  +    NF++ L+    ER   + +  F+  I
Sbjct:   74 PTALKSEICKELRQNQVNTFMLVNDDGELEKETFN----RGIDFIIHMASSMGIPTFTWFPDKAGQYKLDKSSLAIRLEPANWHIIQAMVDFMQAYNWTQVATIVSKKIPNHQNFIKELQLAQKERGLMNNEKLFRFII 208          
BLAST of Glutamate receptor ionotropic, NMDA 2B vs. Planmine SMEST
Match: SMESG000021416.1 (SMESG000021416.1)

HSP 1 Score: 758.444 bits (1957), Expect = 0.000e+0
Identity = 390/789 (49.43%), Postives = 530/789 (67.17%), Query Frame = 2
Query:  812 LEHILAADHRIILFYGMKYDLIIM-----HKIALKDPNLSKIFGAEFVWILCPEAITPTMSVMNKKEKFSPSL-------ELSEDMPPLPGVFGFAYAPTTSMLKDNLNIATSFWKTSVEXXXXXXXXXXXXXXXEILERMIPKLNCQSKVDRNDAWTFGKYIYKFMSTLSVDYNSNFYQFSVHNYLNSTSFLVMNTRSILDKSPLYEMEKEKHFVTSWTKVGTWIMSSTLEEKRTKLQIDGVTWPGEVNKPPLGRPSKFKLRVSTLKEEPFVIFSVKQDKTCGNNALACSVLHDSLSISVDDFEKSKNRTKYLYMG-----NENYTDACCTGMAIDILRELMKDLNFEVDLYEVPDRKWGAWSAEKGWNGLLESLINRKVDMAVSAFKITPNRSEQVDFTVPFQETGIAILVALHEGSISPTAFLKPYDWASWMVILIFSVHCCSTAMFIYEWLSPKGLDRGNVPPREHKFSLFRALWLIWAMLFGASVNVDSPRGMASRFLGCIWALFGLVFLASYTANLAAFMIAKEDHYDLKGLNDWRFQRPWNFKPEFRFATVPFSASEENIALNYPDIALYMRRYNKSSVEEGIRALKQKEIDAFIYDSNVLEFRAAKDEGCKLRTVGNLYAVTGYGIAFPKGSKWYSKVNDLIMQYQKYDLLHRWKTFWLTGACKKTDKLANTNRTLGVRNFISAFXXXXXXXXXXXXXXXCEHLFFRYLRPRMSNLDQYGCCGLISLSMGQLLSFEQTVNQTVDFVKNYKCHNPLCENQIWRLRKELEMSKEIIRKLETSF 3127
            L+ +   + R+ILF+G +Y+L+++          K   L+++FG+ ++W+  P  +TP  + M + E  +P L       ++ +    +PG+F F         K    +A   W  S+  L   L  R+  + + I++++ P   C++K   N     G  +Y+ M ++++  N  +  F  +  +N+T  L+ N++  +                 W KVGTW MSS   +K++ L+IDGVTWPG   KPP GRP KF+LRV+T+KE PFV F   +   C  N+L C V   +  +S    E + N T Y   G     +  Y  ACC+G+ +D+L ELMKDL FEVDL+EVPD KWG W+ + GWNGL++ L +   DMAV++FKITPNRSEQ+DF+VPF +TGIAI+VAL EG ISPTAFL+PYD+ SW VIL+FSVH C  A+FIYEWLSP GLDRGN    EHKFS FR+LWLIW+MLFGA+VN D+PRG ASRFL  IWALF LVFLASYTANLAAFMIAK+D YDL G+ D     P  FKP F FATVP  A+EENI +N+P +  YM+++N+SSVEEGI+ALK  EI+AFIYDSNVLE+RA KDE CKL+TVGNL+A+TGYG+ FPK SKW + +ND I+ Y+    + RWK +WLTGACKK  +L +TN+ LGV+NFISAFILLL G+I+ +LLL+ EH F++YLRP ++N+D+YGCCGL+S+SMGQ+L+FEQ+VNQTVD VK++KC N +CE++  + R E +  K+ +  LE + 
Sbjct:  236 LKELHKNNDRVILFHGTQYELMLLISAVKEYAVDKSSYLNEMFGSNYIWLCSPALVTPVKNEM-RSESINPDLFVIKGSWKVGKVDLQIPGMFVFVTFNNFESYKSKAIMARELWARSLSKLTEILKERHPNNISAIVDKLRPSDLCENK---NPKLKMGPQLYQIMKSMTLKINDEYIGFLNNGAINTTELLIFNSQKKISG-------------LGWHKVGTWSMSSKWGKKKSNLRIDGVTWPGNEIKPPRGRPDKFRLRVTTIKEVPFVQFRESETGNCDGNSLKCWVRDLNRQLS----ESNVNETFYAIFGVNVTSDHPYVPACCSGLTMDMLSELMKDLEFEVDLFEVPDGKWGGWTFD-GWNGLVKVLKDHSADMAVTSFKITPNRSEQIDFSVPFLQTGIAIIVALREGGISPTAFLEPYDYQSWCVILVFSVHACGAALFIYEWLSPHGLDRGNQVTAEHKFSFFRSLWLIWSMLFGAAVNADNPRGTASRFLANIWALFALVFLASYTANLAAFMIAKDDFYDLTGIKDAHLMNPLGFKPPFTFATVPSGATEENIKINFPTMYEYMKKFNRSSVEEGIKALKTGEINAFIYDSNVLEYRATKDENCKLKTVGNLFAMTGYGVGFPKSSKWLNLINDRILNYESNGKMQRWKQYWLTGACKKDRRLDSTNKRLGVKNFISAFILLLGGIILCSLLLLLEHTFYKYLRPHLTNIDKYGCCGLVSISMGQILNFEQSVNQTVDMVKHHKCSNIICESKWLKARNEADRLKKRVEMLEDAL 1002          

HSP 2 Score: 73.1738 bits (178), Expect = 1.038e-12
Identity = 42/139 (30.22%), Postives = 76/139 (54.68%), Query Frame = 3
Query:  303 PQAIHNAICKILQPKRRKKXXXXXXXXXXXXDNLDAKSSKVIEYFVNLISNLGVPTITWLPSQLGQILFEEGPMALRLEPSNKHLAEAMFDFVQTYNWXXXXXXXXXXXXXXXXFVQMLKEVITERESSSKDDYFKLKI 719
            P A+ + ICK L+  +    + V     +  +  +    + I++ +++ S++G+PT TW P + GQ   ++  +A+RLEP+N H+ +AM DF+Q YNW  V  +VS  +    NF++ L+    ER   + +  F+  I
Sbjct:   68 PTALKSEICKELRQNQVNTFMLVNDDGELEKETFN----RGIDFIIHMASSMGIPTFTWFPDKAGQYKLDKSSLAIRLEPANWHIIQAMVDFMQAYNWTQVATIVSKKIPNHQNFIKELQLAQKERGLMNNEKLFRFII 202          
The following BLAST results are available for this feature:
BLAST of Glutamate receptor ionotropic, NMDA 2B vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
GRIN2A3.558e-9336.98glutamate ionotropic receptor NMDA type subunit 2A... [more]
GRIN2A2.181e-9236.98glutamate ionotropic receptor NMDA type subunit 2A... [more]
GRIN2A7.985e-9236.98glutamate ionotropic receptor NMDA type subunit 2A... [more]
GRIN2A7.985e-9236.98glutamate ionotropic receptor NMDA type subunit 2A... [more]
GRIN2D2.091e-9137.23glutamate ionotropic receptor NMDA type subunit 2D... [more]
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BLAST of Glutamate receptor ionotropic, NMDA 2B vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
nmr-21.735e-13038.80NMDA class glutamate Receptor [Source:UniProtKB/T... [more]
nmr-24.023e-10443.35NMDA class glutamate Receptor [Source:UniProtKB/T... [more]
nmr-16.019e-3827.49NMDA class glutamate Receptor; NMDA-type ionotropi... [more]
nmr-16.019e-3827.49NMDA class glutamate Receptor; NMDA-type ionotropi... [more]
glr-41.860e-3428.77GLutamate Receptor family (AMPA) [Source:UniProtK... [more]
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BLAST of Glutamate receptor ionotropic, NMDA 2B vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Nmdar26.837e-15434.91gene:FBgn0053513 transcript:FBtr0091453[more]
Nmdar26.837e-15434.91gene:FBgn0053513 transcript:FBtr0301842[more]
Nmdar26.837e-15434.91gene:FBgn0053513 transcript:FBtr0091454[more]
Nmdar23.498e-15334.91gene:FBgn0053513 transcript:FBtr0301843[more]
Nmdar21.935e-15234.91gene:FBgn0053513 transcript:FBtr0301844[more]
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BLAST of Glutamate receptor ionotropic, NMDA 2B vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
grin2cb2.992e-9533.33glutamate receptor, ionotropic, N-methyl D-asparta... [more]
grin2cb2.992e-9533.33glutamate receptor, ionotropic, N-methyl D-asparta... [more]
BX294659.13.836e-9533.33glutamate receptor, ionotropic, N-methyl D-asparta... [more]
grin2aa2.115e-9235.22glutamate receptor, ionotropic, N-methyl D-asparta... [more]
grin2db4.298e-9235.69glutamate receptor, ionotropic, N-methyl D-asparta... [more]
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BLAST of Glutamate receptor ionotropic, NMDA 2B vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
sdr42e18.982e-9737.38short chain dehydrogenase/reductase family 42E, me... [more]
GRIN2C7.924e-9539.13glutamate receptor, ionotropic, N-methyl D-asparta... [more]
GRIN2C1.249e-9439.34glutamate receptor, ionotropic, N-methyl D-asparta... [more]
GRIN2A2.941e-9431.69glutamate receptor, ionotropic, N-methyl D-asparta... [more]
GRIN2C1.605e-9338.43glutamate receptor, ionotropic, N-methyl D-asparta... [more]
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BLAST of Glutamate receptor ionotropic, NMDA 2B vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Grin2a2.316e-9236.98glutamate receptor, ionotropic, NMDA2A (epsilon 1)... [more]
Grin2a2.316e-9236.98glutamate receptor, ionotropic, NMDA2A (epsilon 1)... [more]
Grin2a2.316e-9236.98glutamate receptor, ionotropic, NMDA2A (epsilon 1)... [more]
Grin2d1.843e-9137.23glutamate receptor, ionotropic, NMDA2D (epsilon 4)... [more]
Grin2d1.843e-9137.23glutamate receptor, ionotropic, NMDA2D (epsilon 4)... [more]
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BLAST of Glutamate receptor ionotropic, NMDA 2B vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q00959|NMDE1_RAT1.200e-9137.18Glutamate receptor ionotropic, NMDA 2A OS=Rattus n... [more]
sp|P35436|NMDE1_MOUSE1.620e-9136.98Glutamate receptor ionotropic, NMDA 2A OS=Mus musc... [more]
sp|Q5IS45|NMDE1_PANTR2.950e-9136.98Glutamate receptor ionotropic, NMDA 2A OS=Pan trog... [more]
sp|Q12879|NMDE1_HUMAN3.834e-9136.98Glutamate receptor ionotropic, NMDA 2A OS=Homo sap... [more]
sp|B7ZSK1|NMDE1_XENLA6.960e-9132.74Glutamate receptor ionotropic, NMDA 2A OS=Xenopus ... [more]
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BLAST of Glutamate receptor ionotropic, NMDA 2B vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A267FAS35.706e-649.50Uncharacterized protein OS=Macrostomum lignano OX=... [more]
A0A267EW570.000e+049.50Uncharacterized protein OS=Macrostomum lignano OX=... [more]
A0A267G7X70.000e+046.90Uncharacterized protein (Fragment) OS=Macrostomum ... [more]
A0A267F5H50.000e+046.90Uncharacterized protein (Fragment) OS=Macrostomum ... [more]
A0A1I8JBQ40.000e+048.21Uncharacterized protein OS=Macrostomum lignano OX=... [more]
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BLAST of Glutamate receptor ionotropic, NMDA 2B vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
grin2ca2.788e-9332.13glutamate receptor ionotropic, NMDA 2C-like [Sourc... [more]
grin2cb4.076e-9335.09glutamate receptor ionotropic, NMDA 2C [Source:NCB... [more]
grin2cb7.015e-9135.09glutamate receptor ionotropic, NMDA 2C [Source:NCB... [more]
grin2da2.035e-9037.34glutamate receptor ionotropic, NMDA 2D-like [Sourc... [more]
grin2ab3.435e-9036.48glutamate receptor, ionotropic, N-methyl D-asparta... [more]
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BLAST of Glutamate receptor ionotropic, NMDA 2B vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ENSPMAT00000010716.11.627e-9039.66pep scaffold:Pmarinus_7.0:GL476465:413535:454465:1... [more]
ENSPMAT00000000889.11.069e-3134.85pep scaffold:Pmarinus_7.0:GL476542:184998:205948:1... [more]
gria1b4.353e-2826.33glutamate receptor, ionotropic, AMPA 1b [Source:ZF... [more]
ENSPMAT00000005084.15.563e-2627.93pep scaffold:Pmarinus_7.0:GL476900:54926:87395:-1 ... [more]
ENSPMAT00000000621.17.038e-1727.32pep scaffold:Pmarinus_7.0:GL479810:19620:30867:-1 ... [more]
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BLAST of Glutamate receptor ionotropic, NMDA 2B vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Glutamate receptor ionotropic, NMDA 2B vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO355457.530e-5930.92Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO448421.328e-5833.53Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO343634.865e-4027.88Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO489862.100e-3728.09Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO375512.599e-3628.04Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Glutamate receptor ionotropic, NMDA 2B vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
grin2ca1.946e-9534.59glutamate ionotropic receptor NMDA type subunit 2C... [more]
ENSORLT00000013760.21.224e-9332.22glutamate receptor ionotropic, NMDA 2C [Source:NCB... [more]
ENSORLT00000011525.23.696e-9037.69glutamate receptor ionotropic, NMDA 2A [Source:NCB... [more]
ENSORLT00000040618.14.485e-9037.69glutamate receptor ionotropic, NMDA 2A [Source:NCB... [more]
grin2aa3.032e-8836.68glutamate ionotropic receptor NMDA type subunit 2A... [more]
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BLAST of Glutamate receptor ionotropic, NMDA 2B vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000048391.10.000e+099.79SMESG000048391.1[more]
SMESG000048395.10.000e+0100.00SMESG000048395.1[more]
SMESG000021416.11.025e-1249.43SMESG000021416.1[more]
SMESG000021416.11.040e-1249.43SMESG000021416.1[more]
SMESG000021416.11.038e-1249.43SMESG000021416.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30028945 ID=SMED30028945|Name=Glutamate receptor ionotropic, NMDA 2B|organism=Schmidtea mediterranea sexual|type=transcript|length=3582bp
TTTCAAACAATTTGCACTCGAGAATTTCCCCATCAAAATCAGGAAAATTC
TTAAAAGACTGTACATCTTAAATAAAAAATATGATAAAGCTATTCCAAAT
AATTATCCCTTTACTGAATTGGATAATCAAATGCGCGGGAAGAGATGTTA
TTCATAATCTGGAAGTGATTTGTGCTACATCTGGTTTATCGAAGACTCTT
GGGTCAGCGATGACAACAGAAATCGAAGAGCTGAATAAGCAGATTAGTGA
TAAATATGTTATTCATAACACTGGTTGCAGCCGAATCTCAGCCTGGGATG
CGCCTCAAGCCATTCATAATGCGATTTGCAAAATTCTTCAACCAAAACGC
AGAAAGAAATCTGTTACTGTTACGTCAACGGTTCTTGTAGTTAGCGATAA
TCTAGATGCAAAATCATCAAAAGTTATAGAATATTTCGTCAATTTAATAT
CCAATCTTGGAGTTCCAACAATTACATGGCTTCCAAGCCAATTAGGTCAA
ATTTTATTTGAAGAGGGTCCAATGGCGTTACGTCTTGAACCTAGTAACAA
ACATCTAGCTGAAGCAATGTTCGACTTCGTACAGACTTACAACTGGAATA
TGGTAGTTCTCTTGGTCAGTTTGAATCTTTCTGGATCCATGAACTTTGTC
CAAATGCTCAAGGAAGTCATTACCGAACGAGAATCATCAAGCAAGGATGA
TTATTTCAAATTAAAAATAGTTGATGAATATTTTTTGACGGATTCATTGA
TCAGAGTGAAATTATGAGTGTCCTAAAATCTGAAGAGCGCCTGTCCTCCT
ACAAGAAAAGCCTGGAGCACATTCTGGCAGCTGACCATAGAATAATACTG
TTTTATGGAATGAAGTACGATTTGATTATCATGCATAAAATTGCTTTGAA
AGATCCTAACCTATCGAAAATATTCGGAGCAGAATTCGTGTGGATTTTAT
GCCCAGAAGCCATAACCCCTACTATGTCAGTGATGAATAAAAAAGAAAAG
TTCTCACCGAGTTTGGAATTATCAGAGGACATGCCCCCGTTGCCTGGAGT
ATTTGGTTTTGCATATGCTCCAACAACATCAATGCTAAAAGACAATTTAA
ACATTGCGACTTCTTTTTGGAAAACATCTGTGGAAAATTTGATAAATAAC
TTAACAATCAGGAACAATATCTCACGGACAGAAATTTTAGAGAGAATGAT
TCCTAAGTTGAATTGTCAATCAAAGGTTGACCGGAACGATGCCTGGACAT
TTGGAAAATATATTTACAAATTTATGAGCACACTATCAGTCGATTATAAC
TCAAATTTCTATCAATTTTCTGTCCATAACTATTTGAACAGCACGAGCTT
CCTTGTGATGAATACGAGATCCATTCTCGACAAGAGCCCTTTATATGAAA
TGGAGAAGGAAAAGCATTTTGTTACAAGTTGGACCAAGGTTGGAACCTGG
ATCATGAGTAGCACTTTGGAGGAAAAGAGAACAAAACTTCAAATTGACGG
AGTGACTTGGCCAGGTGAAGTTAATAAACCTCCACTTGGAAGGCCATCAA
AATTCAAATTAAGAGTTTCAACATTAAAAGAAGAACCTTTCGTGATCTTT
AGTGTTAAACAAGACAAAACTTGTGGAAATAACGCTTTGGCATGTTCAGT
TTTGCATGACTCGCTCTCGATTTCAGTAGATGATTTTGAAAAATCAAAAA
ATCGTACAAAATATTTGTACATGGGAAACGAAAACTATACGGACGCGTGC
TGTACAGGAATGGCAATAGATATTTTACGAGAATTAATGAAAGATCTAAA
TTTTGAAGTTGATCTTTATGAAGTTCCTGATCGAAAATGGGGAGCGTGGA
GTGCAGAAAAAGGATGGAATGGATTGCTCGAATCTTTGATTAATAGAAAA
GTCGATATGGCAGTCAGTGCTTTCAAGATAACACCGAACCGATCAGAGCA
GGTCGATTTCACGGTGCCATTCCAAGAAACTGGAATCGCTATACTTGTGG
CGCTTCATGAAGGATCTATTTCACCGACTGCTTTTCTCAAACCTTACGAT
TGGGCGTCATGGATGGTTATCTTGATATTCAGTGTCCATTGCTGCAGCAC
TGCTATGTTCATTTATGAATGGCTCAGTCCCAAAGGTCTCGACAGAGGAA
ATGTTCCTCCCAGAGAGCATAAATTCTCCTTGTTTCGTGCGTTGTGGTTG
ATTTGGGCGATGCTTTTCGGAGCATCCGTAAACGTGGATTCTCCTCGAGG
AATGGCAAGCAGATTTTTGGGATGTATTTGGGCGCTATTTGGATTGGTTT
TTCTGGCGAGTTATACAGCAAATCTAGCTGCTTTTATGATTGCCAAGGAA
GATCATTACGATTTAAAAGGTCTTAATGATTGGAGATTTCAAAGACCATG
GAACTTTAAACCCGAATTTCGGTTTGCTACAGTCCCTTTCAGTGCTTCCG
AAGAAAATATAGCCCTCAACTACCCTGATATAGCTTTGTATATGAGAAGA
TATAACAAAAGCAGCGTTGAAGAAGGAATTCGAGCATTAAAACAAAAAGA
AATCGATGCTTTTATCTACGACTCAAACGTTCTTGAGTTCCGAGCCGCCA
AAGACGAAGGCTGCAAACTTCGGACCGTTGGTAATCTATATGCAGTTACT
GGATATGGAATCGCTTTCCCAAAAGGTTCTAAATGGTATTCAAAGGTCAA
TGATCTTATAATGCAATATCAAAAATACGATCTGCTTCATCGGTGGAAAA
CATTCTGGTTGACTGGTGCTTGCAAGAAAACCGATAAGTTAGCAAACACA
AATCGAACATTGGGGGTGCGAAATTTTATCAGTGCTTTTATTTTGCTACT
CACCGGGCTCATTATTTCGACTCTCTTGTTGATTTGTGAGCACCTTTTCT
TTCGATATCTGCGACCAAGGATGAGCAATCTCGATCAGTACGGATGTTGC
GGTTTGATCAGTTTGAGTATGGGACAGCTTCTTTCGTTTGAGCAAACCGT
CAACCAGACCGTGGATTTTGTGAAAAACTATAAATGTCACAATCCGTTGT
GTGAAAATCAAATATGGAGACTACGTAAAGAATTGGAAATGTCAAAAGAA
ATAATTCGGAAACTCGAGACATCTTTTGAAGGTCTTAATTCTTCATTAAG
GTCAATGTCATCTTTCCCAAAGTTCGTGAATCAGGCAGAAGCAGACAATA
AAAACTCAGCCTCTCTTCTAAAATCAAAAGAATATCATTCTTTCAATAAT
CCTCCAGTGGATAATTCATGCCAAATTCAAGACGCGGATGACAAAAATAA
AAATTCGAATTCTTCTTTCCAGTTAGCTCATGAAATTTCTCGGAGAAAAT
CCAGCTCTTTCATATCTATCAACTCAATACCGGAGAAACTGACGTACACT
TGCTTCGTTGAAAATTCATTGCTCTCACAGACCCAATTACATTCCAATAG
TAGAAAATGTAGAAATTTTATCATTCAGCAAGAGTCGTCGTTGTAAATTG
TTTTTGAATATCTGAGACTGTCATCTGATTGTGGAAAATCTAGCATTTTA
ATTGTTTTTGGTGCCATAGAATCAATTCTGTG
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protein sequence of SMED30028945-orf-1

>SMED30028945-orf-1 ID=SMED30028945-orf-1|Name=SMED30028945-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=911bp
MSVLKSEERLSSYKKSLEHILAADHRIILFYGMKYDLIIMHKIALKDPNL
SKIFGAEFVWILCPEAITPTMSVMNKKEKFSPSLELSEDMPPLPGVFGFA
YAPTTSMLKDNLNIATSFWKTSVENLINNLTIRNNISRTEILERMIPKLN
CQSKVDRNDAWTFGKYIYKFMSTLSVDYNSNFYQFSVHNYLNSTSFLVMN
TRSILDKSPLYEMEKEKHFVTSWTKVGTWIMSSTLEEKRTKLQIDGVTWP
GEVNKPPLGRPSKFKLRVSTLKEEPFVIFSVKQDKTCGNNALACSVLHDS
LSISVDDFEKSKNRTKYLYMGNENYTDACCTGMAIDILRELMKDLNFEVD
LYEVPDRKWGAWSAEKGWNGLLESLINRKVDMAVSAFKITPNRSEQVDFT
VPFQETGIAILVALHEGSISPTAFLKPYDWASWMVILIFSVHCCSTAMFI
YEWLSPKGLDRGNVPPREHKFSLFRALWLIWAMLFGASVNVDSPRGMASR
FLGCIWALFGLVFLASYTANLAAFMIAKEDHYDLKGLNDWRFQRPWNFKP
EFRFATVPFSASEENIALNYPDIALYMRRYNKSSVEEGIRALKQKEIDAF
IYDSNVLEFRAAKDEGCKLRTVGNLYAVTGYGIAFPKGSKWYSKVNDLIM
QYQKYDLLHRWKTFWLTGACKKTDKLANTNRTLGVRNFISAFILLLTGLI
ISTLLLICEHLFFRYLRPRMSNLDQYGCCGLISLSMGQLLSFEQTVNQTV
DFVKNYKCHNPLCENQIWRLRKELEMSKEIIRKLETSFEGLNSSLRSMSS
FPKFVNQAEADNKNSASLLKSKEYHSFNNPPVDNSCQIQDADDKNKNSNS
SFQLAHEISRRKSSSFISINSIPEKLTYTCFVENSLLSQTQLHSNSRKCR
NFIIQQESSL*
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protein sequence of SMED30028945-orf-2

>SMED30028945-orf-2 ID=SMED30028945-orf-2|Name=SMED30028945-orf-2|organism=Schmidtea mediterranea sexual|type=polypeptide|length=229bp
MIKLFQIIIPLLNWIIKCAGRDVIHNLEVICATSGLSKTLGSAMTTEIEE
LNKQISDKYVIHNTGCSRISAWDAPQAIHNAICKILQPKRRKKSVTVTST
VLVVSDNLDAKSSKVIEYFVNLISNLGVPTITWLPSQLGQILFEEGPMAL
RLEPSNKHLAEAMFDFVQTYNWNMVVLLVSLNLSGSMNFVQMLKEVITER
ESSSKDDYFKLKIVDEYFLTDSLIRVKL*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: molecular function
TermDefinition
GO:0015276ligand-gated ion channel activity
GO:0038023signaling receptor activity
GO:0004872receptor activity
GO:0005216ion channel activity
GO:0004970ionotropic glutamate receptor activity
GO:0005234extracellular-glutamate-gated ion channel activity
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000418head
PLANA:0000419prepharyngeal region
PLANA:0003104enteric muscle cell
Vocabulary: INTERPRO
TermDefinition
IPR001828ANF_lig-bd_rcpt
IPR028082Peripla_BP_I
IPR001508Iono_rcpt_met
IPR019594Glu/Gly-bd
IPR001320Iontro_rcpt
Vocabulary: cellular component
TermDefinition
GO:0016020membrane
GO:0005886plasma membrane
GO:0016021integral component of membrane
GO:0098794postsynapse
Vocabulary: biological process
TermDefinition
GO:0006811ion transport
GO:0006810transport
GO:0034220ion transmembrane transport
GO:0035235ionotropic glutamate receptor signaling pathway
GO:0060079excitatory postsynaptic potential
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
NoneNo IPR availableGENE3DG3DSA:3.40.50.2300coord: 43..154
e-value: 6.3E-9
score: 37.1
NoneNo IPR availableGENE3DG3DSA:3.40.50.2300coord: 155..203
e-value: 6.3E-9
score: 37.1
NoneNo IPR availableCDDcd06351PBP1_iGluR_N_LIVBP_likecoord: 124..206
e-value: 2.37926E-8
score: 51.3553
NoneNo IPR availableSIGNALP_EUKSignalP-noTMSignalP-noTMcoord: 1..20
score: 0.581
IPR001828Receptor, ligand binding regionPFAMPF01094ANF_receptorcoord: 43..185
e-value: 3.3E-7
score: 29.7
IPR028082Periplasmic binding protein-like ISUPERFAMILYSSF53822Periplasmic binding protein-like Icoord: 112..181