mutS protein homolog 4

Overview


Name	mutS protein homolog 4
Smed ID	SMED30028928
Length (bp)	2984

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of mutS protein homolog 4 (SMED30028928) t-SNE clustered cells

Violin plots show distribution of expression levels for mutS protein homolog 4 (SMED30028928) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of mutS protein homolog 4 (SMED30028928) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for mutS protein homolog 4 (SMED30028928) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30028928

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 3

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication
protonephridia	SMED30028928	h1SMcG0001344	dd_Smed_v4_12806_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
nervous system	SMED30028928	h1SMcG0001344	dd_Smed_v4_12806_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
parenchymal cell	SMED30028928	h1SMcG0001344	dd_Smed_v4_12806_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018

Note: Hover over icons to view figure legend

Homology

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BLAST of mutS protein homolog 4 vs. Ensembl Human
Match: MSH4 (mutS homolog 4 [Source:HGNC Symbol;Acc:HGNC:7327])

HSP 1 Score: 677.552 bits (1747), Expect = 0.000e+0
Identity = 332/742 (44.74%), Postives = 505/742 (68.06%), Query Frame = 1

Query:  526 LIEGRGVASGEIGIASVDLKNPELELSQFSDSIGYSRTLSKLYLKDPVEIVFPHTMCENGVRSKLFQIVSEFMHKSSITTIHRRYYNDKNGKEIIQHLCHKDYTSSILYESREKYYALAACAAIIKYVEFIQNILFAPGSLQIIFSGSVKCAIIDIASVRNLELVENSKDLTENGSLFSALNFTTTNGGYRLLRANILQPSFDIPTITSRYDCVEELMNNAELFFTLKSQIKHFVSLNHLLSLCVQLPKNQTVKSAENTITQVIALKHVMELIPTLRATLQSFKSSLFIEYHSLLVDSRYDEILSIINVVVHEDVHFEKGILQMRSQKLFAIKDGINVILDIARRSYSEQIEALRDEVQALSVEHALPLRVAFSNSRGFYIQLPLTNSSVKPRLSLP--FIKVAIVKNFITCTTEKIMKFNERLKGALAEIYLTAELLLSELIKAIRVHMGVLYRLSEISATLDLLLSFAQVSKMQNYIRPEFTDTLAIKNCRNPLLDRLSNKEAISNHVYAANLSNFTIVTGANMSGKSMYLRQIALVQIMGQIGCFIPAEYASFRLSDHLFTRIGVDDDIQSNSSTFTIEMREMSYIINTITDNSLVLIDELGRGTSFDEGLGICFAICEHLLQTKAFIFIATHFRELSKLEILYPNVQNVNFEVKNLSESDGDENHLLFTYKCVRGVCPDFTNAMKLAKLSNLPKQLLFEAEKIYGRLGDSNELIIEVKSQFIRNIHKGRPLGKERGVF 2745
            ++EGRG+A GEIG+AS+DLKNP++ LSQF+D+  Y++ ++KL +  P+EI+  +T C  G  +KLF +++E     + TTI R+Y+N+  G E I+ LC  ++ S++L E + KYY LAA AA++KYVEFIQN ++AP SL+I F GS + A+ID +S +NLEL+ N++D   N +LF  LN+T T GG R LR+NIL+P  DI TI  R DCV+EL+ + ELFF L+S I  F+    LLS+ VQ+PK  TV +AE+ IT +I LKH +EL+  L+  +++  + L   Y+  L D R+  IL  I  V+++D  + KG L MR+QK +A++  IN  LDIARR+Y+E ++ +   +  L  +++LPLR +FS++RGF+IQ+  T+    P   LP  FIK++ VKN  + T+  ++K NER + +L EIY    +++ +L+  I  H+  LY+LS+  + LD+LLSFA    + +Y+RPEFTDTLAIK   +P+L+++S ++ I+N+ Y    SNF I+TG NMSGKS YL+QIAL QIM QIG ++PAEY+SFR++  +FTRI  DDDI++NSSTF  EM+E++YI++   D SL+LIDELGRGT+ +EG+GIC+A+CE+LL  KAF   ATHF EL  ++ LYPNV+N++FEV+++  +  ++  +L+TYK  +G+  +    +K A++S+LP  ++           D+ E+  ++  Q ++N      + ++R V+
Sbjct:  160 VVEGRGLARGEIGMASIDLKNPQIILSQFADNTTYAKVITKLKILSPLEIIMSNTACAVGNSTKLFTLITENFKNVNFTTIQRKYFNETKGLEYIEQLCIAEF-STVLMEVQSKYYCLAAVAALLKYVEFIQNSVYAPKSLKICFQGSEQTAMIDSSSAQNLELLINNQDYRNNHTLFGVLNYTKTPGGSRRLRSNILEPLVDIETINMRLDCVQELLQDEELFFGLQSVISRFLDTEQLLSVLVQIPKQDTVNAAESKITNLIYLKHTLELVDPLKIAMKNCNTPLLRAYYGSLEDKRFGIILEKIKTVINDDARYMKGCLNMRTQKCYAVRSNINEFLDIARRTYTEIVDDIAGMISQLGEKYSLPLRTSFSSARGFFIQM-TTDCIALPSDQLPSEFIKISKVKNSYSFTSADLIKMNERCQESLREIYHMTYMIVCKLLSEIYEHIHCLYKLSDTVSMLDMLLSFAHACTLSDYVRPEFTDTLAIKQGWHPILEKISAEKPIANNTYVTEGSNFLIITGPNMSGKSTYLKQIALCQIMAQIGSYVPAEYSSFRIAKQIFTRISTDDDIETNSSTFMKEMKEIAYILHNANDKSLILIDELGRGTNTEEGIGICYAVCEYLLSLKAFTLFATHFLELCHIDALYPNVENMHFEVQHVKNTSRNKEAILYTYKLSKGLTEEKNYGLKAAEVSSLPPSIVL----------DAKEITTQITRQILQNQRSTPEMERQRAVY 889

[Close]

BLAST of mutS protein homolog 4 vs. Ensembl Human
Match: MSH2 (mutS homolog 2 [Source:HGNC Symbol;Acc:HGNC:7325])

HSP 1 Score: 205.682 bits (522), Expect = 5.591e-54
Identity = 206/723 (28.49%), Postives = 331/723 (45.78%), Query Frame = 1

Query:  556 EIGIASVDLKNPELELSQFSDSIGYSRTLSKLYLKDPVEIVFPHTMCENGVRSKLFQIVSEFMHKSSITTIHRRYYNDKNGKEIIQHLCH-------KDYTSSILYESREKYYALAACAAIIKYVEFIQNIL-FAPGSLQII-FSGSVKCAIIDIASVRNLELVENS-KDLTENGSLFSALNFTTTNGGYRLLRANILQPSFDIPTITSRYDCVEELMNNAELFFTLKSQI-KHFVSLNHL----------LSLCVQLPKNQTVKSAENTITQVIAL--KHVMELIPTLRATLQSFKSSLFIEYHSLLVDSRYDEILSIINVVVHE---DVHFEKGILQMRSQKLFAIKDGINVILDIARRSYSEQIEALRDEVQALSVEHALPLRVAFSNSRGFYIQLPLTNSSVKPRLSLPFIKVAIVKNFITCTTEKIMKFNERLKGALAEIYLTAELLLSELIKAIRVHMGVLYRLSEISATLDLLLSFAQVSKMQN--YIRPEFTDT----LAIKNCRNPLLDRLSNKEAISNHVY-AANLSNFTIVTGANMSGKSMYLRQIALVQIMGQIGCFIPAEYASFRLSDHLFTRIGVDDDIQSNSSTFTIEMREMSYIINTITDNSLVLIDELGRGTSFDEGLGICFAICEHLL-QTKAFIFIATHFRELSKLEILYPNVQNVNFEVKNLSESDGDENHLLFTYKCVRGVCPDFTNAMKLAKLSNLPKQLL 2622
            ++G+  VD    +L L +F D+  +S   + L    P E V P      G   KL QI+     +  I    R+   D + K+I Q L         +   S++L E  E   A+++ +A+IK++E + +   F    L    FS  +K   +DIA+VR L L + S +D T + SL + LN   T  G RL+   I QP  D   I  R + VE  + +AEL  TL+  + + F  LN L          L  C +L   Q +    N I  +     KH   L+      L   +S  F ++  ++     +  L +  V  HE      F+  + ++R            ++ D+ ++  S  I A RD    L ++    +++  S   G+Y ++      V  R +  F  V I KN +  T  K+   NE       E     + ++ E++     ++  +  L+++ A LD ++SFA VS      Y+RP   +     + +K  R+  ++       I N VY   +   F I+TG NM GKS Y+RQ  ++ +M QIGCF+P E A   + D +  R+G  D      STF  EM E + I+ + T +SL++IDELGRGTS  +G G+ +AI E++  +  AF   ATHF EL+ L    P V N++       E+      L   Y+  +GVC D +  + +A+L+N PK ++
Sbjct:  160 QVGVGYVDSIQRKLGLCEFPDNDQFSNLEALLIQIGPKECVLPGGETA-GDMGKLRQII----QRGGILITERKKA-DFSTKDIYQDLNRLLKGKKGEQMNSAVLPE-MENQVAVSSLSAVIKFLELLSDDSNFGQFELTTFDFSQYMK---LDIAAVRALNLFQGSVEDTTGSQSLAALLNKCKTPQGQRLVNQWIKQPLMDKNRIEERLNLVEAFVEDAELRQTLQEDLLRRFPDLNRLAKKFQRQAANLQDCYRL--YQGINQLPNVIQALEKHEGKHQKLLLAVFVTPLTDLRSD-FSKFQEMI-----ETTLDMDQVENHEFLVKPSFDPNLSELRE-----------IMNDLEKKMQSTLISAARD----LGLDPGKQIKLDSSAQFGYYFRVTCKEEKVL-RNNKNFSTVDIQKNGVKFTNSKLTSLNEEYTKNKTEYEEAQDAIVKEIVNISSGYVEPMQTLNDVLAQLDAVVSFAHVSNGAPVPYVRPAILEKGQGRIILKASRHACVEVQDEIAFIPNDVYFEKDKQMFHIITGPNMGGKSTYIRQTGVIVLMAQIGCFVPCESAEVSIVDCILARVGAGDSQLKGVSTFMAEMLETASILRSATKDSLIIIDELGRGTSTYDGFGLAWAISEYIATKIGAFCMFATHFHELTALANQIPTVNNLHVTALTTEET------LTMLYQVKKGVC-DQSFGIHVAELANFPKHVI 841

[Close]

BLAST of mutS protein homolog 4 vs. Ensembl Human
Match: MSH2 (mutS homolog 2 [Source:HGNC Symbol;Acc:HGNC:7325])

HSP 1 Score: 205.297 bits (521), Expect = 6.214e-54
Identity = 206/723 (28.49%), Postives = 331/723 (45.78%), Query Frame = 1

Query:  556 EIGIASVDLKNPELELSQFSDSIGYSRTLSKLYLKDPVEIVFPHTMCENGVRSKLFQIVSEFMHKSSITTIHRRYYNDKNGKEIIQHLCH-------KDYTSSILYESREKYYALAACAAIIKYVEFIQNIL-FAPGSLQII-FSGSVKCAIIDIASVRNLELVENS-KDLTENGSLFSALNFTTTNGGYRLLRANILQPSFDIPTITSRYDCVEELMNNAELFFTLKSQI-KHFVSLNHL----------LSLCVQLPKNQTVKSAENTITQVIAL--KHVMELIPTLRATLQSFKSSLFIEYHSLLVDSRYDEILSIINVVVHE---DVHFEKGILQMRSQKLFAIKDGINVILDIARRSYSEQIEALRDEVQALSVEHALPLRVAFSNSRGFYIQLPLTNSSVKPRLSLPFIKVAIVKNFITCTTEKIMKFNERLKGALAEIYLTAELLLSELIKAIRVHMGVLYRLSEISATLDLLLSFAQVSKMQN--YIRPEFTDT----LAIKNCRNPLLDRLSNKEAISNHVY-AANLSNFTIVTGANMSGKSMYLRQIALVQIMGQIGCFIPAEYASFRLSDHLFTRIGVDDDIQSNSSTFTIEMREMSYIINTITDNSLVLIDELGRGTSFDEGLGICFAICEHLL-QTKAFIFIATHFRELSKLEILYPNVQNVNFEVKNLSESDGDENHLLFTYKCVRGVCPDFTNAMKLAKLSNLPKQLL 2622
            ++G+  VD    +L L +F D+  +S   + L    P E V P      G   KL QI+     +  I    R+   D + K+I Q L         +   S++L E  E   A+++ +A+IK++E + +   F    L    FS  +K   +DIA+VR L L + S +D T + SL + LN   T  G RL+   I QP  D   I  R + VE  + +AEL  TL+  + + F  LN L          L  C +L   Q +    N I  +     KH   L+      L   +S  F ++  ++     +  L +  V  HE      F+  + ++R            ++ D+ ++  S  I A RD    L ++    +++  S   G+Y ++      V  R +  F  V I KN +  T  K+   NE       E     + ++ E++     ++  +  L+++ A LD ++SFA VS      Y+RP   +     + +K  R+  ++       I N VY   +   F I+TG NM GKS Y+RQ  ++ +M QIGCF+P E A   + D +  R+G  D      STF  EM E + I+ + T +SL++IDELGRGTS  +G G+ +AI E++  +  AF   ATHF EL+ L    P V N++       E+      L   Y+  +GVC D +  + +A+L+N PK ++
Sbjct:  160 QVGVGYVDSIQRKLGLCEFPDNDQFSNLEALLIQIGPKECVLPGGETA-GDMGKLRQII----QRGGILITERKKA-DFSTKDIYQDLNRLLKGKKGEQMNSAVLPE-MENQVAVSSLSAVIKFLELLSDDSNFGQFELTTFDFSQYMK---LDIAAVRALNLFQGSVEDTTGSQSLAALLNKCKTPQGQRLVNQWIKQPLMDKNRIEERLNLVEAFVEDAELRQTLQEDLLRRFPDLNRLAKKFQRQAANLQDCYRL--YQGINQLPNVIQALEKHEGKHQKLLLAVFVTPLTDLRSD-FSKFQEMI-----ETTLDMDQVENHEFLVKPSFDPNLSELRE-----------IMNDLEKKMQSTLISAARD----LGLDPGKQIKLDSSAQFGYYFRVTCKEEKVL-RNNKNFSTVDIQKNGVKFTNSKLTSLNEEYTKNKTEYEEAQDAIVKEIVNISSGYVEPMQTLNDVLAQLDAVVSFAHVSNGAPVPYVRPAILEKGQGRIILKASRHACVEVQDEIAFIPNDVYFEKDKQMFHIITGPNMGGKSTYIRQTGVIVLMAQIGCFVPCESAEVSIVDCILARVGAGDSQLKGVSTFMAEMLETASILRSATKDSLIIIDELGRGTSTYDGFGLAWAISEYIATKIGAFCMFATHFHELTALANQIPTVNNLHVTALTTEET------LTMLYQVKKGVC-DQSFGIHVAELANFPKHVI 841

[Close]

BLAST of mutS protein homolog 4 vs. Ensembl Human
Match: MSH2 (mutS homolog 2 [Source:HGNC Symbol;Acc:HGNC:7325])

HSP 1 Score: 205.297 bits (521), Expect = 6.370e-54
Identity = 206/723 (28.49%), Postives = 331/723 (45.78%), Query Frame = 1

Query:  556 EIGIASVDLKNPELELSQFSDSIGYSRTLSKLYLKDPVEIVFPHTMCENGVRSKLFQIVSEFMHKSSITTIHRRYYNDKNGKEIIQHLCH-------KDYTSSILYESREKYYALAACAAIIKYVEFIQNIL-FAPGSLQII-FSGSVKCAIIDIASVRNLELVENS-KDLTENGSLFSALNFTTTNGGYRLLRANILQPSFDIPTITSRYDCVEELMNNAELFFTLKSQI-KHFVSLNHL----------LSLCVQLPKNQTVKSAENTITQVIAL--KHVMELIPTLRATLQSFKSSLFIEYHSLLVDSRYDEILSIINVVVHE---DVHFEKGILQMRSQKLFAIKDGINVILDIARRSYSEQIEALRDEVQALSVEHALPLRVAFSNSRGFYIQLPLTNSSVKPRLSLPFIKVAIVKNFITCTTEKIMKFNERLKGALAEIYLTAELLLSELIKAIRVHMGVLYRLSEISATLDLLLSFAQVSKMQN--YIRPEFTDT----LAIKNCRNPLLDRLSNKEAISNHVY-AANLSNFTIVTGANMSGKSMYLRQIALVQIMGQIGCFIPAEYASFRLSDHLFTRIGVDDDIQSNSSTFTIEMREMSYIINTITDNSLVLIDELGRGTSFDEGLGICFAICEHLL-QTKAFIFIATHFRELSKLEILYPNVQNVNFEVKNLSESDGDENHLLFTYKCVRGVCPDFTNAMKLAKLSNLPKQLL 2622
            ++G+  VD    +L L +F D+  +S   + L    P E V P      G   KL QI+     +  I    R+   D + K+I Q L         +   S++L E  E   A+++ +A+IK++E + +   F    L    FS  +K   +DIA+VR L L + S +D T + SL + LN   T  G RL+   I QP  D   I  R + VE  + +AEL  TL+  + + F  LN L          L  C +L   Q +    N I  +     KH   L+      L   +S  F ++  ++     +  L +  V  HE      F+  + ++R            ++ D+ ++  S  I A RD    L ++    +++  S   G+Y ++      V  R +  F  V I KN +  T  K+   NE       E     + ++ E++     ++  +  L+++ A LD ++SFA VS      Y+RP   +     + +K  R+  ++       I N VY   +   F I+TG NM GKS Y+RQ  ++ +M QIGCF+P E A   + D +  R+G  D      STF  EM E + I+ + T +SL++IDELGRGTS  +G G+ +AI E++  +  AF   ATHF EL+ L    P V N++       E+      L   Y+  +GVC D +  + +A+L+N PK ++
Sbjct:  160 QVGVGYVDSIQRKLGLCEFPDNDQFSNLEALLIQIGPKECVLPGGETA-GDMGKLRQII----QRGGILITERKKA-DFSTKDIYQDLNRLLKGKKGEQMNSAVLPE-MENQVAVSSLSAVIKFLELLSDDSNFGQFELTTFDFSQYMK---LDIAAVRALNLFQGSVEDTTGSQSLAALLNKCKTPQGQRLVNQWIKQPLMDKNRIEERLNLVEAFVEDAELRQTLQEDLLRRFPDLNRLAKKFQRQAANLQDCYRL--YQGINQLPNVIQALEKHEGKHQKLLLAVFVTPLTDLRSD-FSKFQEMI-----ETTLDMDQVENHEFLVKPSFDPNLSELRE-----------IMNDLEKKMQSTLISAARD----LGLDPGKQIKLDSSAQFGYYFRVTCKEEKVL-RNNKNFSTVDIQKNGVKFTNSKLTSLNEEYTKNKTEYEEAQDAIVKEIVNISSGYVEPMQTLNDVLAQLDAVVSFAHVSNGAPVPYVRPAILEKGQGRIILKASRHACVEVQDEIAFIPNDVYFEKDKQMFHIITGPNMGGKSTYIRQTGVIVLMAQIGCFVPCESAEVSIVDCILARVGAGDSQLKGVSTFMAEMLETASILRSATKDSLIIIDELGRGTSTYDGFGLAWAISEYIATKIGAFCMFATHFHELTALANQIPTVNNLHVTALTTEET------LTMLYQVKKGVC-DQSFGIHVAELANFPKHVI 841

[Close]

BLAST of mutS protein homolog 4 vs. Ensembl Human
Match: MSH2 (mutS homolog 2 [Source:HGNC Symbol;Acc:HGNC:7325])

HSP 1 Score: 205.297 bits (521), Expect = 6.576e-54
Identity = 206/723 (28.49%), Postives = 331/723 (45.78%), Query Frame = 1

Query:  556 EIGIASVDLKNPELELSQFSDSIGYSRTLSKLYLKDPVEIVFPHTMCENGVRSKLFQIVSEFMHKSSITTIHRRYYNDKNGKEIIQHLCH-------KDYTSSILYESREKYYALAACAAIIKYVEFIQNIL-FAPGSLQII-FSGSVKCAIIDIASVRNLELVENS-KDLTENGSLFSALNFTTTNGGYRLLRANILQPSFDIPTITSRYDCVEELMNNAELFFTLKSQI-KHFVSLNHL----------LSLCVQLPKNQTVKSAENTITQVIAL--KHVMELIPTLRATLQSFKSSLFIEYHSLLVDSRYDEILSIINVVVHE---DVHFEKGILQMRSQKLFAIKDGINVILDIARRSYSEQIEALRDEVQALSVEHALPLRVAFSNSRGFYIQLPLTNSSVKPRLSLPFIKVAIVKNFITCTTEKIMKFNERLKGALAEIYLTAELLLSELIKAIRVHMGVLYRLSEISATLDLLLSFAQVSKMQN--YIRPEFTDT----LAIKNCRNPLLDRLSNKEAISNHVY-AANLSNFTIVTGANMSGKSMYLRQIALVQIMGQIGCFIPAEYASFRLSDHLFTRIGVDDDIQSNSSTFTIEMREMSYIINTITDNSLVLIDELGRGTSFDEGLGICFAICEHLL-QTKAFIFIATHFRELSKLEILYPNVQNVNFEVKNLSESDGDENHLLFTYKCVRGVCPDFTNAMKLAKLSNLPKQLL 2622
            ++G+  VD    +L L +F D+  +S   + L    P E V P      G   KL QI+     +  I    R+   D + K+I Q L         +   S++L E  E   A+++ +A+IK++E + +   F    L    FS  +K   +DIA+VR L L + S +D T + SL + LN   T  G RL+   I QP  D   I  R + VE  + +AEL  TL+  + + F  LN L          L  C +L   Q +    N I  +     KH   L+      L   +S  F ++  ++     +  L +  V  HE      F+  + ++R            ++ D+ ++  S  I A RD    L ++    +++  S   G+Y ++      V  R +  F  V I KN +  T  K+   NE       E     + ++ E++     ++  +  L+++ A LD ++SFA VS      Y+RP   +     + +K  R+  ++       I N VY   +   F I+TG NM GKS Y+RQ  ++ +M QIGCF+P E A   + D +  R+G  D      STF  EM E + I+ + T +SL++IDELGRGTS  +G G+ +AI E++  +  AF   ATHF EL+ L    P V N++       E+      L   Y+  +GVC D +  + +A+L+N PK ++
Sbjct:  160 QVGVGYVDSIQRKLGLCEFPDNDQFSNLEALLIQIGPKECVLPGGETA-GDMGKLRQII----QRGGILITERKKA-DFSTKDIYQDLNRLLKGKKGEQMNSAVLPE-MENQVAVSSLSAVIKFLELLSDDSNFGQFELTTFDFSQYMK---LDIAAVRALNLFQGSVEDTTGSQSLAALLNKCKTPQGQRLVNQWIKQPLMDKNRIEERLNLVEAFVEDAELRQTLQEDLLRRFPDLNRLAKKFQRQAANLQDCYRL--YQGINQLPNVIQALEKHEGKHQKLLLAVFVTPLTDLRSD-FSKFQEMI-----ETTLDMDQVENHEFLVKPSFDPNLSELRE-----------IMNDLEKKMQSTLISAARD----LGLDPGKQIKLDSSAQFGYYFRVTCKEEKVL-RNNKNFSTVDIQKNGVKFTNSKLTSLNEEYTKNKTEYEEAQDAIVKEIVNISSGYVEPMQTLNDVLAQLDAVVSFAHVSNGAPVPYVRPAILEKGQGRIILKASRHACVEVQDEIAFIPNDVYFEKDKQMFHIITGPNMGGKSTYIRQTGVIVLMAQIGCFVPCESAEVSIVDCILARVGAGDSQLKGVSTFMAEMLETASILRSATKDSLIIIDELGRGTSTYDGFGLAWAISEYIATKIGAFCMFATHFHELTALANQIPTVNNLHVTALTTEET------LTMLYQVKKGVC-DQSFGIHVAELANFPKHVI 841

[Close]

BLAST of mutS protein homolog 4 vs. Ensembl Celegans
Match: him-14 (MutS protein homolog him-14 [Source:UniProtKB/Swiss-Prot;Acc:Q23405])

HSP 1 Score: 348.591 bits (893), Expect = 1.714e-105
Identity = 221/724 (30.52%), Postives = 398/724 (54.97%), Query Frame = 1

Query:  523 LLIEGRGVASGEIGIASVDLKNPELELSQFSDSIGYSRTLSKLYLKDPVEIVFPHTMCENGVRSKLFQIVSEFMHKSSITTIHRRYYNDKNGKEIIQHLCHKDYTSSILYESREKYYALAACAAIIKYVEFIQNILFAPGSLQIIFSGSVKCAIIDIASVRNLELVENSK-------DLTENGSLFSALNFTTTNGGYRLLRANILQPSFDIPTITSRYDCVEELMNNAELFFTLKSQIKHFVSLNHLLSLCVQLPKNQTVKSAENTITQVIALKHVMELIPTLRATLQS--FKSSLFIEYHSLLVDSRYDEILSIINVVVHEDV-HFEKGILQMRSQKLFAIKDGINVILDIARRSYSEQIEALRDEVQALSVEHAL----PLRVAFSNSRGFYIQLPLTNSSVKPRLSLPFIKVAIVKNFITCTTEKIMKFNERLKGALAEIYLTAELLLSELIKAIRVHMGVLYRLSEISATLDLLLSFAQVSKMQNYIRPEFTDTLAIKNCRNPLLDRLSNKEAISNHVYAANLSNFTIVTGANMSGKSMYLRQIALVQIMGQIGCFIPAEYASFRLSDHLFTRIGVDDDIQSNSSTFTIEMREMSYIINTITDNSLVLIDELGRGTSFDEGLGICFAICEHLLQTKAFIFIATHFRELSKLEILYPNVQNVNFEVKNLSESDGDENHLLFTYKCVRGVCPDFTNAMKLAKLSNLPKQLLFEAEKIYGRL 2652
            +++EGRG   G IGIA  D   PE+ L +F DS  Y+   + + + +  +IV  +   E G    L + +     ++S+ +I  +Y+N + G+  +Q L + +  S++      +  AL A A ++KY+   + + F   SL+I   G     +ID  S  +LE+V+           + +  +L S LN T T  GYRLLR+++LQPS D+  I SR + +EEL+   +L   L+  +     L+ ++++C+Q   + TV+ +E  I Q+I L H +++I  +R  L S   KS++ IE    L D R+D+I++I+   V + +   +K  L +++ K +AI+  + V LD+AR++Y E I  + +E  A  +         +R++FS SRGF+    +T  +    +   F+ V   +  +T  + K++ +N+RL+  +AE++L +++++ ++I+ ++  + VLY   +  +++D L   A  S +++  +P F  + +I   R+P+LD   +++ I+N         F I+TG NM+GKS YL+Q A + IM QIGCFIPA YAS  + + +F+R+G +D++  N S F  EM + + I+     NSLV++DEL R TS +EG+ I +AICE +L+ +++ F+ATHF +++ L      + N +F    L ++D +       +K +RG         +L +LS +P +++  A+ +   L
Sbjct:   56 VVMEGRGSCEGHIGIALHDTCFPEIHLCEFVDSREYTTLKTMINVHEAFDIVIQNGNEERGSTKLLGEALMTAFPEASLQSISSKYFNSERGERQLQSLMNAE-VSTVSEGCLRRTLALGALAVLLKYIHETRCVFFRVKSLRIKEMGVNDTCMIDFVSWESLEIVDADDASKARKFQMKQKRTLMSVLNHTVTTNGYRLLRSSVLQPSTDVYLIQSRQEAIEELIGKPQLKDKLRRTLSRAHELDRVIAMCIQTSTSWTVRESEAKINQIIKLMHTLKVIQGIRTLLHSAKMKSNILIEKTEFLKDPRFDQIMNILVEKVDDSLLDGKKNSLHLQNTKCYAIRHFVAVQLDLARQTYEEIIRNV-EETGAREIAEYFHGNSSVRLSFSQSRGFHYTF-VTRQAESVTIPRYFLDVFRNRTTVTFNSRKVIAYNDRLEQVVAEMFLASDVIVCDMIEEMQPMIPVLYYAMDALSSIDFLCGLATYSDLRDTCKPTFGPSFSISQGRHPILDWDDSEKTITNDTCLTRDRRFGIITGPNMAGKSTYLKQTAQLAIMAQIGCFIPANYASLPIFNRIFSRMGHNDELIRNKSAFASEMSDAAAIVQYADKNSLVVLDELARSTSTEEGIAITYAICEKVLKLQSYTFLATHFLDIAALANYSNAIDNYHF----LPQTDENSTK---KHKLLRGQYRGPLYGFELVELSTIPDEVIEHAQSLATEL 769

[Close]

BLAST of mutS protein homolog 4 vs. Ensembl Celegans
Match: msh-2 (MSH (MutS Homolog) family [Source:UniProtKB/TrEMBL;Acc:Q9TXR4])

HSP 1 Score: 154.451 bits (389), Expect = 3.549e-38
Identity = 194/763 (25.43%), Postives = 337/763 (44.17%), Query Frame = 1

Query:  541 GVASGEIGIASVDLKNPELELSQFSDSIGYSRTLSKLYLKDPVEIVFPHTMCENGVRSKLFQIVSEF----MHKSS-----------ITTIHRRYYND-----KNGKEIIQHLCHKDYTSSILYESREKYYALAACAAIIKYVEFIQNILFAPGSLQIIFSGSVKCAIIDIASVRNLELVE---NSKDLTENGSLFSALNFTTTNGGYRLLRANILQPSFDIPTITSRYDCVEELMNNAELFFTLKSQIKHFVS-----LNHLLSLCVQLPKNQTVKSA---ENTITQVIALKHVMELIPTLRATLQSFKSSLF--IEYHSLLVDSRYDEILSIINVVVHEDVHFEKGILQMRSQKLFAIKDGINVILDIARRSYSEQIEALRDEVQALSVEHALPLRVAFSNSRGFYIQLPLTNS-SVKPRLS--LPFIKVAIVK---NFITCTTEKIMKFNERLKGALAEIYLTAELLLSELIKAIRVHMGVLYRLSEISATLDLLLSFAQVSKMQN--YIRPEF----TDTLAIKNCRNPLLDRLSNKEAISNHVYAANLSNFTIVTGANMSGKSMYLRQIALVQIMGQIGCFIPAEYASFRLSDHLFTRIGVDDDIQSNSSTFTIEMREMSYIINTITDNSLVLIDELGRGTSFDEGLGICFAICEHLL-QTKAFIFIATHFRELSKLEILYPNVQNVNFEVKNLSESDGDENHLLFTYKCVRGVCPDFTNAMKLAKLSNLPKQLLFEAEKIYGRLGDSNELIIEVKSQ 2691
            G     + + + D  N  + +S++ D+  +S+T   ++   P E +  +   E  V  K  +I S F    +H              I ++H  Y ++     +N KE +Q          IL+ +    Y+++   +I  Y                   G+    +ID  +V  LEL +   N  + + N +L++ LN   T  G +LLR  + +P   I  I  R D VE L  N  +   L+  I   +         L+  C     N+  ++A   E    Q+I L    +  P++   L+S  + +   +E   +L D  +D      N  +   V F   I ++ S+KL    + +  + +  R+ YS + E                L++  ++  GFY ++ L    S++ +    L   K + VK     ++   ++ ++F+  LK   AE     E ++S L K     + ++  ++++ ATLD+ +S +  +   +  Y RP      +  L +K CR+P+++  S K  I N V   +     I+TGANM GKS YLR  AL  ++ QIG F+P   A+  + D +FTR+G  D      STF  EM + S I+   T NS V+IDELGRGTS  +G GI  AI + +L + +     ATHF E+ KL    P    +   V    + + +E H+L  YK   GV    +  +++AK+  + + ++ +A ++    G   +L+I+ K +
Sbjct:  137 GDDDNRVTLCAWDAGNVRIVISEYIDTPSFSQTEQCIFGLCPTEYILVN---EGSVAPKAKKIASMFTRMEVHNKQQLKPKSQWSDVIESVHLDYKDEAEKQNENIKECLQ----------ILHSNAADEYSISEKYSIFNY-------------------GTHGNMLIDSCAVEALELFQLNYNYLEKSNNLTLYNVLNKCKTLPGEKLLRDWLSRPLCQIDHINERLDIVEALFENQTIRQKLRDSILARMPDCSQLARRLMRKCTLQDLNRFYQAATLLETVEMQLIQLSEAEQFAPSINRLLKSEITEILKKVERFQVLCDEFFDFDYEKENKEIRVRVDFVPEIQEI-SEKL----EQMERVAEKLRKKYSAKFECDN-------------LKLDKNSQYGFYFRVTLKEEKSIRKKDVHILETTKGSGVKFSVGELSDINDEFLEFH--LKYTRAE-----EEVISMLCKKAEEFIPLIPAMAQLIATLDVFVSLSTFAATSSGIYTRPNLLPLGSKRLELKQCRHPVIEGNSEKPFIPNDV-VLDKCRLIILTGANMGGKSTYLRSAALSILLAQIGSFVPCSSATISVVDGIFTRVGASDKQSQGISTFMAEMLDCSAILQRATKNSFVVIDELGRGTSTFDGFGIASAIAQDILNRIQCLSIFATHFHEMGKL-AEQPGAVALQMGV----QIENNEIHML--YKVFEGVA-QCSFGLQVAKMVGIDENVINKAAQLLE--GLEKKLVIDSKKK 831

[Close]

BLAST of mutS protein homolog 4 vs. Ensembl Celegans
Match: msh-6 (MSH (MutS Homolog) family [Source:UniProtKB/TrEMBL;Acc:Q9N3T8])

HSP 1 Score: 132.88 bits (333), Expect = 4.071e-31
Identity = 157/602 (26.08%), Postives = 272/602 (45.18%), Query Frame = 1

Query:  949 QIIFSGSVKCAIIDIASVRNLELVENSKDLTENGSLFSALNFTTTNGGYRLLRANILQPSFDIPTITSRYDCVEELMN-NAELFFTLKSQ-IKHFVSLNHLLSLCVQLP-KNQTVKSAENTITQVIALKHVMELIPTLRATLQSFK--SSLFIEYHSLLVDSR----YDEILSIINVV--VHEDVHFEKGILQMRSQKLFAIKDGINVI-------LDIARRSYSEQIEALRDEVQALSVEHALPLRVAFSNSRGFYIQLPLTNSSVKPRLSLPFIKVAIVKNFITCTTEKIMKFNERLKGALAEIYLTAELLLSELIKAIRVHMG----VLYRLSEISATLDLLLSFAQVSKMQNY--IRPEF----TDT-LAIKNCRNPLLDRLSNKEAISNHVYAANLSNF-------TIVTGANMSGKSMYLRQIALVQIMGQIGCFIPAEYASFRLS--DHLFTRIGVDDDIQSNSSTFTIEMREMSYIINTITDNSLVLIDELGRGTSFDEGLGICFAICEHLLQTKAF-IFIATHFRELSKLEILYPNVQNVNFE--VKNLSESDGDENHLLFTYKCVRGVCPDFTNAMKLAKLSNLPKQLLFEA 2631
            +I ++G  K  I+D  ++ NL +V N +D +   SL+  +N  +T  G RLLR+ +LQP+ D   +  R   ++ L++ +A  F T  +  +K    L+ LL     +  K ++ K  ++       +K   + I  L A +  FK  + L  EY  +  +       DE+L     +  V E+++F + +    +    A+KDG  V         D A     E +  L D   +++ +++  ++   S    + +++P  N+ V     L   +    K FI  +T      +E+L  AL  +      L  +  + +    G    +     ++ ++ D+L S A  +K   +    PEF    TD  L +    +P L   S  E      + AN +          ++TG NM GKS  +RQ A++ I+  IG  +PA   S RL+  D +FTRIG +D I    STF IE++E   ++   T +SL+L+DELGRGTS  +G  I  A+ + +    A   F +TH+  +      +PNV+  + +  V   +  D     + F Y+   G+CP  +     AKL+ +  Q++  A
Sbjct:  563 KIDWNG--KNLILDGTALENLNIVPNGRD-SHLTSLYYVINKCSTPFGRRLLRSWLLQPTCDPKKLEQRQKAIKWLVSPDASSFMTTATATLKKIPDLDRLLQKIHTIGLKYRSEKHPDSRAIFFDTIKTNQKKIAELLAAIDGFKLCNKLRKEYIKVQKEGEGCELLDELLGNEQEMEEVDENIYFFEKMFDRST----AMKDGKIVPNAGCDEEYDEALNRVKEALNELNDYKDSVAKKYSCSIKFVDSGKVKYLLEMP-ENTKVSSSFELKSRR----KGFIRYSTPD----SEQLVAALDAVEKEKSKLGDDATRRVFEQFGHKNPIWLETVKLVSSFDVLTSLALFAKSSPFEMCMPEFDFNATDPYLIVDKGVHPCLALQSRNEVTQTTSFIANSTTMGASEAAVMLLTGPNMGGKSTLMRQTAVLAILAHIGSMVPA--FSMRLTPIDRIFTRIGANDRIMCGESTFFIELKETDIMLKNATKHSLLLVDELGRGTSTFDGTAIASAVLQKISDDLACRTFFSTHYHSICDSFTNHPNVRLAHMKCVVDKENNEDPTMEDVTFLYELESGICPK-SYGFYAAKLAGIDHQVVRNA 1145

[Close]

BLAST of mutS protein homolog 4 vs. Ensembl Celegans
Match: msh-5 (MutS protein homolog 5 [Source:UniProtKB/Swiss-Prot;Acc:Q19272])

HSP 1 Score: 109.768 bits (273), Expect = 5.595e-24
Identity = 142/594 (23.91%), Postives = 260/594 (43.77%), Query Frame = 1

Query:  985 IDIASVRNLELV----ENSKDLTENGSLFSALNFTTTNGGYRLLRANILQPSFDIPTITSRYDCVEELMN--NAELFFTLKSQIKHFVSLNHLLSLCVQLPKNQTVKSAENTITQVIALKHVMELIPTLRATLQSFKSSLFIEYHSLLVDSRYDEILSIINVVVHEDVHFEKGILQMRSQKLFAIKDGINVILDIARRSYSEQIEALRDEVQALSVEHALPLRVAFSNSRGFYIQLPLTNSSVKPRLSLP---FIKVAIVKNFITCTTEKIMKFN---ERLKGALAEIYL-----TAELLLSELIKAIRVHMGVLYRLSEISATLDLLLSFAQVSKMQNYIRPEFTDTLAIKNCR--NPLLDRLSNKEAISNHVYAANLS-NFTIVTGANMSGKSMYLRQIALVQIMGQIGCFIPAEYASFRLSDHLFTRIGVDDDIQSNSSTFTIEMREMSYIINTITDNSLVLIDELGRGTSFDEGLGICFAICEHLLQTKA----FIFIATHFRELSKLEILYPNVQN-VNFEVKNLSESDGDENHLLFTYKCVRGVCPDFTNAMKLAKLSNLPKQLLFEAEKIYGRLGDSNELIIEVKSQ 2691
            ID  +++ L+++    EN K   +  SL+  ++   +  G + LR     P+ D   + SR  CV       NAE+   L S +    +LN +     Q    Q +   E  ++ V AL  ++ +I       Q+  S  F     LL +      +S I V+    ++F +  +Q R      + +GI+  LD  R +Y      L    +       LP    +SN    YI L      V   LS+P    ++       +  T E +   N    RL     +I +        ++L+   + ++    ++  LS I++ +D+L+SF  ++    +  P   D   I+     +P+   +  K  + N V +       +I+TG N  GKS+Y++ I ++  +  IG F+PA +A   + D + TR+   D +    STF  ++ +++  +   T NSLV+IDE G+GT  + GL +  ++  + +   A     IF+++HF  L     L  N+   + F V  L E+ G    + + ++   G+  D + A+ +AK   +P  ++  A +IY  L  +  L+ E+K++
Sbjct:  280 IDFNTIQALDILPKETENKKTFGQGRSLYQLMDKCRSTVGKKCLRKWFRNPTTDRDDLVSRQKCVHYFKQDWNAEVTAKLSSILGRVKALNSVFQK-FQSGTAQLIH-WECFVSTVNALVEILNII------RQTPISKEFPVESDLLRE------VSEIAVIAGSIINFAESKIQGR----VTVMNGIDEELDEIRDTYENMPMVLTAIAKQEEARLGLP---PYSNVACVYIPL------VGFVLSVPRDYGVESQPDMTLLYSTHEDLRVRNATTSRLDDEFGDILMRLIDSQTAIILTLKTRVMKKKRSIIKLLS-IASRIDVLISFGLIAAQNGWNCPALVDEPVIEAVELYHPISVLVVKKSFVPNQVSSGRDGIKASIITGPNACGKSVYMKSIGIMVFLSHIGSFVPARHAKIGIVDRIVTRMFTVDSVLDGMSTFAKDVEQVALALRKATGNSLVIIDEFGKGTMTEVGLSLLASVMTYWMNRGADRCPHIFLSSHFHALPNYIPLETNIATFLTFTV--LREAGG---KIKYLFRMTPGLV-DCSFALSVAKEEGIPPPVIGRACRIYKALK-AGTLLKEIKAE 838

[Close]

BLAST of mutS protein homolog 4 vs. Ensembl Celegans
Match: msh-5 (MutS protein homolog 5 [Source:UniProtKB/Swiss-Prot;Acc:Q19272])

HSP 1 Score: 101.679 bits (252), Expect = 1.158e-21
Identity = 74/280 (26.43%), Postives = 141/280 (50.36%), Query Frame = 1

Query: 1876 LYRLSEISATLDLLLSFAQVSKMQNYIRPEFTDTLAIKNCR--NPLLDRLSNKEAISNHVYAANLS-NFTIVTGANMSGKSMYLRQIALVQIMGQIGCFIPAEYASFRLSDHLFTRIGVDDDIQSNSSTFTIEMREMSYIINTITDNSLVLIDELGRGTSFDEGLGICFAICEHLLQTKA----FIFIATHFRELSKLEILYPNVQN-VNFEVKNLSESDGDENHLLFTYKCVRGVCPDFTNAMKLAKLSNLPKQLLFEAEKIYGRLGDSNELIIEVKSQ 2691
            + +L  I++ +D+L+SF  ++    +  P   D   I+     +P+   +  K  + N V +       +I+TG N  GKS+Y++ I ++  +  IG F+PA +A   + D + TR+   D +    STF  ++ +++  +   T NSLV+IDE G+GT  + GL +  ++  + +   A     IF+++HF  L     L  N+   + F V  L E+ G    + + ++   G+  D + A+ +AK   +P  ++  A +IY  L  +  L+ E+K++
Sbjct:  120 IIKLLSIASRIDVLISFGLIAAQNGWNCPALVDEPVIEAVELYHPISVLVVKKSFVPNQVSSGRDGIKASIITGPNACGKSVYMKSIGIMVFLSHIGSFVPARHAKIGIVDRIVTRMFTVDSVLDGMSTFAKDVEQVALALRKATGNSLVIIDEFGKGTMTEVGLSLLASVMTYWMNRGADRCPHIFLSSHFHALPNYIPLETNIATFLTFTV--LREAGG---KIKYLFRMTPGLV-DCSFALSVAKEEGIPPPVIGRACRIYKAL-KAGTLLKEIKAE 392

[Close]

BLAST of mutS protein homolog 4 vs. Ensembl Fly
Match: spel1 (gene:FBgn0015546 transcript:FBtr0344018)

HSP 1 Score: 162.155 bits (409), Expect = 2.144e-40
Identity = 105/321 (32.71%), Postives = 167/321 (52.02%), Query Frame = 1

Query: 1726 VAIVKNFITCTTEKIMKFNERLKGALAEIYLTAELLLSELIKAIRVHMGVLYRLSEISATLDLLLSFAQVSKMQN--YIRP----EFTDTLAIKNCRNPLLDRLSNKEAISNHV-YAANLSNFTIVTGANMSGKSMYLRQIALVQIMGQIGCFIPAEYASFRLSDHLFTRIGVDDDIQSNSSTFTIEMREMSYIINTITDNSLVLIDELGRGTSFDEGLGICFAICEHLL-QTKAFIFIATHFRELSKLEILYPNVQNVNFEVKNLSESDGDENHLLFTYKCVRGVCPDFTNAMKLAKLSNLPKQLLFEAEKIYGRLGDSN 2664
            V ++K  +  T++K+  + +               ++ E+I     +   L  L+   A LD L+SFA  ++     Y+RP    E    L +++ R+P L+   +   I+N V +     N  I+TG NM GKS Y+R +    +M  IG F+P   A+  + D +  R+G  D+I    STF +EM E S II T TD SLV+IDELGRGTS  EG GI ++I EHL  +TK F   ATHF E++KL      V+N +      + +D D+  LL+    VR    + +  +++A+L+N P+ ++  A+++Y    D +
Sbjct:  540 VDVIKGGVRFTSDKLEGYADEFASCRTRYEEQQLSIVEEIIHVAVGYAAPLTLLNNELAQLDCLVSFAIAARSAPTPYVRPKMLEEGARELVLEDVRHPCLELQEHVNFIANSVDFKKEECNMFIITGPNMGGKSTYIRSVGTAVLMAHIGAFVPCSLATISMVDSILGRVGASDNIIKGLSTFMVEMIETSGIIRTATDKSLVIIDELGRGTSTYEGCGIAWSIAEHLAKETKCFTLFATHFHEITKLAETLSTVKNCHMA----AVADADDFTLLYQ---VRSGVMEKSFGIQVARLANFPEHVVQNAQEVYNEFEDEH 853

[Close]

BLAST of mutS protein homolog 4 vs. Ensembl Fly
Match: spel1 (gene:FBgn0015546 transcript:FBtr0344019)

HSP 1 Score: 162.155 bits (409), Expect = 2.144e-40
Identity = 105/321 (32.71%), Postives = 167/321 (52.02%), Query Frame = 1

Query: 1726 VAIVKNFITCTTEKIMKFNERLKGALAEIYLTAELLLSELIKAIRVHMGVLYRLSEISATLDLLLSFAQVSKMQN--YIRP----EFTDTLAIKNCRNPLLDRLSNKEAISNHV-YAANLSNFTIVTGANMSGKSMYLRQIALVQIMGQIGCFIPAEYASFRLSDHLFTRIGVDDDIQSNSSTFTIEMREMSYIINTITDNSLVLIDELGRGTSFDEGLGICFAICEHLL-QTKAFIFIATHFRELSKLEILYPNVQNVNFEVKNLSESDGDENHLLFTYKCVRGVCPDFTNAMKLAKLSNLPKQLLFEAEKIYGRLGDSN 2664
            V ++K  +  T++K+  + +               ++ E+I     +   L  L+   A LD L+SFA  ++     Y+RP    E    L +++ R+P L+   +   I+N V +     N  I+TG NM GKS Y+R +    +M  IG F+P   A+  + D +  R+G  D+I    STF +EM E S II T TD SLV+IDELGRGTS  EG GI ++I EHL  +TK F   ATHF E++KL      V+N +      + +D D+  LL+    VR    + +  +++A+L+N P+ ++  A+++Y    D +
Sbjct:  540 VDVIKGGVRFTSDKLEGYADEFASCRTRYEEQQLSIVEEIIHVAVGYAAPLTLLNNELAQLDCLVSFAIAARSAPTPYVRPKMLEEGARELVLEDVRHPCLELQEHVNFIANSVDFKKEECNMFIITGPNMGGKSTYIRSVGTAVLMAHIGAFVPCSLATISMVDSILGRVGASDNIIKGLSTFMVEMIETSGIIRTATDKSLVIIDELGRGTSTYEGCGIAWSIAEHLAKETKCFTLFATHFHEITKLAETLSTVKNCHMA----AVADADDFTLLYQ---VRSGVMEKSFGIQVARLANFPEHVVQNAQEVYNEFEDEH 853

[Close]

BLAST of mutS protein homolog 4 vs. Ensembl Fly
Match: spel1 (gene:FBgn0015546 transcript:FBtr0080630)

HSP 1 Score: 162.155 bits (409), Expect = 2.144e-40
Identity = 105/321 (32.71%), Postives = 167/321 (52.02%), Query Frame = 1

Query: 1726 VAIVKNFITCTTEKIMKFNERLKGALAEIYLTAELLLSELIKAIRVHMGVLYRLSEISATLDLLLSFAQVSKMQN--YIRP----EFTDTLAIKNCRNPLLDRLSNKEAISNHV-YAANLSNFTIVTGANMSGKSMYLRQIALVQIMGQIGCFIPAEYASFRLSDHLFTRIGVDDDIQSNSSTFTIEMREMSYIINTITDNSLVLIDELGRGTSFDEGLGICFAICEHLL-QTKAFIFIATHFRELSKLEILYPNVQNVNFEVKNLSESDGDENHLLFTYKCVRGVCPDFTNAMKLAKLSNLPKQLLFEAEKIYGRLGDSN 2664
            V ++K  +  T++K+  + +               ++ E+I     +   L  L+   A LD L+SFA  ++     Y+RP    E    L +++ R+P L+   +   I+N V +     N  I+TG NM GKS Y+R +    +M  IG F+P   A+  + D +  R+G  D+I    STF +EM E S II T TD SLV+IDELGRGTS  EG GI ++I EHL  +TK F   ATHF E++KL      V+N +      + +D D+  LL+    VR    + +  +++A+L+N P+ ++  A+++Y    D +
Sbjct:  540 VDVIKGGVRFTSDKLEGYADEFASCRTRYEEQQLSIVEEIIHVAVGYAAPLTLLNNELAQLDCLVSFAIAARSAPTPYVRPKMLEEGARELVLEDVRHPCLELQEHVNFIANSVDFKKEECNMFIITGPNMGGKSTYIRSVGTAVLMAHIGAFVPCSLATISMVDSILGRVGASDNIIKGLSTFMVEMIETSGIIRTATDKSLVIIDELGRGTSTYEGCGIAWSIAEHLAKETKCFTLFATHFHEITKLAETLSTVKNCHMA----AVADADDFTLLYQ---VRSGVMEKSFGIQVARLANFPEHVVQNAQEVYNEFEDEH 853

[Close]

BLAST of mutS protein homolog 4 vs. Ensembl Fly
Match: spel1 (gene:FBgn0015546 transcript:FBtr0309281)

HSP 1 Score: 162.155 bits (409), Expect = 2.144e-40
Identity = 105/321 (32.71%), Postives = 167/321 (52.02%), Query Frame = 1

Query: 1726 VAIVKNFITCTTEKIMKFNERLKGALAEIYLTAELLLSELIKAIRVHMGVLYRLSEISATLDLLLSFAQVSKMQN--YIRP----EFTDTLAIKNCRNPLLDRLSNKEAISNHV-YAANLSNFTIVTGANMSGKSMYLRQIALVQIMGQIGCFIPAEYASFRLSDHLFTRIGVDDDIQSNSSTFTIEMREMSYIINTITDNSLVLIDELGRGTSFDEGLGICFAICEHLL-QTKAFIFIATHFRELSKLEILYPNVQNVNFEVKNLSESDGDENHLLFTYKCVRGVCPDFTNAMKLAKLSNLPKQLLFEAEKIYGRLGDSN 2664
            V ++K  +  T++K+  + +               ++ E+I     +   L  L+   A LD L+SFA  ++     Y+RP    E    L +++ R+P L+   +   I+N V +     N  I+TG NM GKS Y+R +    +M  IG F+P   A+  + D +  R+G  D+I    STF +EM E S II T TD SLV+IDELGRGTS  EG GI ++I EHL  +TK F   ATHF E++KL      V+N +      + +D D+  LL+    VR    + +  +++A+L+N P+ ++  A+++Y    D +
Sbjct:  540 VDVIKGGVRFTSDKLEGYADEFASCRTRYEEQQLSIVEEIIHVAVGYAAPLTLLNNELAQLDCLVSFAIAARSAPTPYVRPKMLEEGARELVLEDVRHPCLELQEHVNFIANSVDFKKEECNMFIITGPNMGGKSTYIRSVGTAVLMAHIGAFVPCSLATISMVDSILGRVGASDNIIKGLSTFMVEMIETSGIIRTATDKSLVIIDELGRGTSTYEGCGIAWSIAEHLAKETKCFTLFATHFHEITKLAETLSTVKNCHMA----AVADADDFTLLYQ---VRSGVMEKSFGIQVARLANFPEHVVQNAQEVYNEFEDEH 853

[Close]

BLAST of mutS protein homolog 4 vs. Ensembl Fly
Match: Msh6 (gene:FBgn0036486 transcript:FBtr0075646)

HSP 1 Score: 118.627 bits (296), Expect = 1.145e-26
Identity = 68/197 (34.52%), Postives = 104/197 (52.79%), Query Frame = 1

Query: 2056 ANLSNFTIVTGANMSGKSMYLRQIALVQIMGQIGCFIPAEYASFRLSDHLFTRIGVDDDIQSNSSTFTIEMREMSYIINTITDNSLVLIDELGRGTSFDEGLGICFAICEHLLQTKAFIFIATHFRELSKLEILYPNVQNVNFE-----VKNLSESDGDENHLLFTYKCVRGVCPDFTNAMKLAKLSNLPKQLLFEA 2631
            A+ +  +++TG NM GKS  +R++ L+ IM QIG  IPA      L D +FTR+G  DDI +  STF +E+ E S I+   T +SLVL+DELGRGT+  +G  I  ++   L   K     +TH+  L      + N + +        V+N   +D  +  + F YK   G CP  +     AKL+ +P+ ++  A
Sbjct:  948 ASEAPLSLLTGPNMGGKSTLMREVGLLVIMAQIGAHIPAASCRLSLVDRIFTRLGAQDDILAGHSTFLVELNETSLILKHATCHSLVLLDELGRGTATYDGTAIAASVVNFLANLKCRTLFSTHYHNLID---FFHNDKRITLGHMACMVENEDNADPTQETVTFLYKYTAGACPK-SYGFNAAKLAGMPQGIIKRA 1140

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BLAST of mutS protein homolog 4 vs. Ensembl Zebrafish
Match: msh4 (mutS homolog 4 [Source:ZFIN;Acc:ZDB-GENE-131121-643])

HSP 1 Score: 674.085 bits (1738), Expect = 0.000e+0
Identity = 326/711 (45.85%), Postives = 494/711 (69.48%), Query Frame = 1

Query:  526 LIEGRGVASGEIGIASVDLKNPELELSQFSDSIGYSRTLSKLYLKDPVEIVFPHTMCENGVRSKLFQIVSEFMHKSSITTIHRRYYNDKNGKEIIQHLCHKDYTSSILYESREKYYALAACAAIIKYVEFIQNILFAPGSLQIIFSGSVKCAIIDIASVRNLELVENSKDLTENGSLFSALNFTTTNGGYRLLRANILQPSFDIPTITSRYDCVEELMNNAELFFTLKSQIKHFVSLNHLLSLCVQLPKNQTVKSAENTITQVIALKHVMELIPTLRATLQSFKSSLFIEYHSLLVDSRYDEILSIINVVVHEDVHFEKGILQMRSQKLFAIKDGINVILDIARRSYSEQIEALRDEVQALSVEHALPLRVAFSNSRGFYIQLPLTNSSVKPRLSLP--FIKVAIVKNFITCTTEKIMKFNERLKGALAEIYLTAELLLSELIKAIRVHMGVLYRLSEISATLDLLLSFAQVSKMQNYIRPEFTDTLAIKNCRNPLLDRLSNKEAISNHVYAANLSNFTIVTGANMSGKSMYLRQIALVQIMGQIGCFIPAEYASFRLSDHLFTRIGVDDDIQSNSSTFTIEMREMSYIINTITDNSLVLIDELGRGTSFDEGLGICFAICEHLLQTKAFIFIATHFRELSKLEILYPNVQNVNFEVKNLSESDGDENHLLFTYKCVRGVCPDFTNAMKLAKLSNLPKQLLFEAEKIYGRL 2652
            ++EGRG+A GEIG+AS+++K PEL LSQF D+  Y++ ++KL+   P+EI+ P T    G  +KL+ +++E     + T + RRY+N+K G E IQ LC  ++T+ +L E + KYY LA+ +A++KY EF+Q  ++AP SL++ FSGS + A+ID  S  NLELV N ++     +LF  LN T T+GG R LR+NIL+P  ++ TI SR D ++EL+ N ELFF+LK+ I HF+ ++ LLS  VQ+PK +T+  AE  ITQVI LKH++EL+P+L+  LQ   + L   Y   L D R++ IL  I  ++++D  + KG L MR+QK +A++  ++  LDIARR+Y+E ++ +   V  L  +H LPLR +FSN+RGF+IQ+ L   ++ P   LP  FIKV+  KN  + TT  +MK N+  + AL +I+  + +++S+L+  +   +  LY+LS++ + LD+LLS A    + NY+RPEFTDTLAI+  R+P+L+R+S ++ ISN+ Y +  SNF I+TG NMSGKS +L+Q+ALVQIM QIGCF+PAEYAS R++D +FTRIGVDDD ++NSSTF +EM+E+SYII+  T++SL++IDELGRGTS +EG+GIC ++CE L+  KAF   ATHF EL +L+ LYPNV+N + +V+++   DG    +++TY+  RG   +    ++ A+++NLP  ++ EA+ +  ++
Sbjct:  152 VVEGRGLARGEIGMASINMKYPELVLSQFVDTGTYTKVITKLHNLTPMEILMPDTASVKGQGTKLYSLITETFPSVTFTAVLRRYFNEKKGLEFIQQLCVPEFTT-VLMEVQTKYYCLASASALLKYFEFVQKSIYAPKSLKVTFSGSEQTAMIDAVSASNLELVVNHRNHRSEHTLFGVLNHTKTSGGERRLRSNILEPLLEVDTIKSRQDTIQELLQNEELFFSLKNAIAHFLDIDELLSALVQIPKQETIAVAEAKITQVIQLKHIVELVPSLKVMLQHSTTHLLTAYCKSLEDCRFNSILDHIKSLINDDTSYMKGSLTMRTQKCYAVRPNVSEFLDIARRAYTEVVDDIAGLVAQLGEKHNLPLRTSFSNARGFFIQMKLEGGAL-PGGKLPDEFIKVSKQKNNFSFTTLDLMKMNDHCEEALKDIFHMSYVVVSKLLNEVHEQIHCLYKLSDVVSMLDMLLSLANACTISNYVRPEFTDTLAIQQGRHPVLERISGQQPISNNSYISEGSNFVIITGPNMSGKSTFLKQVALVQIMAQIGCFVPAEYASVRIADQIFTRIGVDDDFETNSSTFMVEMKEVSYIIHNATNSSLIIIDELGRGTSPEEGIGICHSVCEFLINLKAFTLFATHFLELCQLQTLYPNVENQHMQVQHIRTGDGRAERVVYTYQLSRGHSEERNYGIRAAEMTNLPLDIIQEAKTVADKI 860

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BLAST of mutS protein homolog 4 vs. Ensembl Zebrafish
Match: msh4 (mutS homolog 4 [Source:ZFIN;Acc:ZDB-GENE-131121-643])

HSP 1 Score: 587.8 bits (1514), Expect = 0.000e+0
Identity = 303/714 (42.44%), Postives = 462/714 (64.71%), Query Frame = 1

Query:  526 LIEGRGVASGEIGIASVDLKNPELELSQFSDSIGYSRTLSKLYLKDPVEIVFPHTMCENGVRSKLFQIVSEFMHKSSITTIHRRYYNDKNGKEIIQHLCHKDYTSSILYESREKYYALAACAAIIKYVEFIQNILFAPGSLQIIFSGSVKCAIIDIASVRNLELVENSKDLTENGSLFSALNFTTTNGGYRLLRANILQPSFDIPTITSRYDCVEELMNNAELFFTLK---SQIKHFVSLNHLLSLCVQLPKNQTVKSAENTITQVIALKHVMELIPTLRATLQSFKSSLFIEYHSLLVDSRYDEILSIINVVVHEDVHFEKGILQMRSQKLFAIKDGINVILDIARRSYSEQIEALRDEVQALSVEHALPLRVAFSNSRGFYIQLPLTNSSVKPRLSLP--FIKVAIVKNFITCTTEKIMKFNERLKGALAEIYLTAELLLSELIKAIRVHMGVLYRLSEISATLDLLLSFAQVSKMQNYIRPEFTDTLAIKNCRNPLLDRLSNKEAISNHVYAANLSNFTIVTGANMSGKSMYLRQIALVQIMGQIGCFIPAEYASFRLSDHLFTRIGVDDDIQSNSSTFTIEMREMSYIINTITDNSLVLIDELGRGTSFDEGLGICFAICEHLLQTKAFIFIATHFRELSKLEILYPNVQNVNFEVKNLSESDGDENHLLFTYKCVRGVCPDFTNAMKLAKLSNLPKQLLFEAEKIYGRL 2652
            ++EGRG+A GEIG+AS+++K PEL LSQF D+  Y++ ++KL+   P+EI+ P T    G  +KL+ +++E     + T + RRY+N+K G E IQ LC  ++T+ +L E + KYY LA+ +A++KY EF+Q  ++AP SL++ FSGS + A+ID  S  NLELV N ++     +LF  LN T T+GG R LR+NIL+P  ++ TI SR D ++ +      FF+LK   + I HF+ ++ LLS  VQ+PK                                         ++S+L     D I S+IN    +D  + KG L MR+QK +A++  ++  LDIARR+Y+E ++ +   V  L  +H LPLR +FSN+RGF+IQ+ L   ++ P   LP  FIKV+  KN  + TT  +MK N+  + AL +I+  + +++S+L+  +   +  LY+LS++ + LD+LLS A    + NY+RPEFTDTLAI+  R+P+L+R+S ++ ISN+ Y +  SNF I+TG NMSGKS +L+Q+ALVQIM QIGCF+PAEYAS R++D +FTRIGVDDD ++NSSTF +EM+E+SYII+  T++SL++IDELGRGTS +EG+GIC ++CE L+  KAF   ATHF EL +L+ LYPNV+N + +V+++   DG    +++TY+  RG   +    ++ A+++NLP  ++ EA+ +  ++
Sbjct:   64 VVEGRGLARGEIGMASINMKYPELVLSQFVDTGTYTKVITKLHNLTPMEILMPDTASVKGQGTKLYSLITETFPSVTFTAVLRRYFNEKKGLEFIQQLCVPEFTT-VLMEVQTKYYCLASASALLKYFEFVQKSIYAPKSLKVTFSGSEQTAMIDAVSASNLELVVNHRNHRSEHTLFGVLNHTKTSGGERRLRSNILEPLLEVDTIKSRQDTIQVI-----FFFSLKFSHTSIAHFLDIDELLSALVQIPK-----------------------------------------FNSIL-----DHIKSLIN----DDTSYMKGSLTMRTQKCYAVRPNVSEFLDIARRAYTEVVDDIAGLVAQLGEKHNLPLRTSFSNARGFFIQMKLEGGAL-PGGKLPDEFIKVSKQKNNFSFTTLDLMKMNDHCEEALKDIFHMSYVVVSKLLNEVHEQIHCLYKLSDVVSMLDMLLSLANACTISNYVRPEFTDTLAIQQGRHPVLERISGQQPISNNSYISEGSNFVIITGPNMSGKSTFLKQVALVQIMAQIGCFVPAEYASVRIADQIFTRIGVDDDFETNSSTFMVEMKEVSYIIHNATNSSLIIIDELGRGTSPEEGIGICHSVCEFLINLKAFTLFATHFLELCQLQTLYPNVENQHMQVQHIRTGDGRAERVVYTYQLSRGHSEERNYGIRAAEMTNLPLDIIQEAKTVADKI 720

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BLAST of mutS protein homolog 4 vs. Ensembl Zebrafish
Match: msh4 (mutS homolog 4 [Source:ZFIN;Acc:ZDB-GENE-131121-643])

HSP 1 Score: 587.03 bits (1512), Expect = 0.000e+0
Identity = 304/714 (42.58%), Postives = 465/714 (65.13%), Query Frame = 1

Query:  526 LIEGRGVASGEIGIASVDLKNPELELSQFSDSIGYSRTLSKLYLKDPVEIVFPHTMCENGVRSKLFQIVSEFMHKSSITTIHRRYYNDKNGKEIIQHLCHKDYTSSILYESREKYYALAACAAIIKYVEFIQNILFAPGSLQIIFSGSVKCAIIDIASVRNLELVENSKDLTENGSLFSALNFTTTNGGYRLLRANILQPSFDIPTITSRYDCVEELMNNAELFFTLK---SQIKHFVSLNHLLSLCVQLPKNQTVKSAENTITQVIALKHVMELIPTLRATLQSFKSSLFIEYHSLLVDSRYDEILSIINVVVHEDVHFEKGILQMRSQKLFAIKDGINVILDIARRSYSEQIEALRDEVQALSVEHALPLRVAFSNSRGFYIQLPLTNSSVKPRLSLP--FIKVAIVKNFITCTTEKIMKFNERLKGALAEIYLTAELLLSELIKAIRVHMGVLYRLSEISATLDLLLSFAQVSKMQNYIRPEFTDTLAIKNCRNPLLDRLSNKEAISNHVYAANLSNFTIVTGANMSGKSMYLRQIALVQIMGQIGCFIPAEYASFRLSDHLFTRIGVDDDIQSNSSTFTIEMREMSYIINTITDNSLVLIDELGRGTSFDEGLGICFAICEHLLQTKAFIFIATHFRELSKLEILYPNVQNVNFEVKNLSESDGDENHLLFTYKCVRGVCPDFTNAMKLAKLSNLPKQLLFEAEKIYGRL 2652
            ++EGRG+A GEIG+AS+++K PEL LSQF D+  Y++ ++KL+   P+EI+ P T    G  +KL+ +++E     + T + RRY+N+K G E IQ LC  ++T+ +L E + KYY LA+ +A++KY EF+Q  ++AP SL++ FSGS + A+ID  S  NLELV N ++ +E+ +LF  LN T T+GG R LR+NIL+P  ++ TI SR D ++ +      FF+LK   + I HF+ ++ LLS  VQ+PK                                         ++S+L     D I S+IN    +D  + KG L MR+QK +A++  ++  LDIARR+Y+E ++ +   V  L  +H LPLR +FSN+RGF+IQ+ L   ++ P   LP  FIKV+  KN  + TT  +MK N+  + AL +I+  + +++S+L+  +   +  LY+LS++ + LD+LLS A    + NY+RPEFTDTLAI+  R+P+L+R+S ++ ISN+ Y +  SNF I+TG NMSGKS +L+Q+ALVQIM QIGCF+PAEYAS R++D +FTRIGVDDD ++NSSTF +EM+E+SYII+  T++SL++IDELGRGTS +EG+GIC ++CE L+  KAF   ATHF EL +L+ LYPNV+N + +V+++   DG    +++TY+  RG   +    ++ A+++NLP  ++ EA+ +  ++
Sbjct:   99 VVEGRGLARGEIGMASINMKYPELVLSQFVDTGTYTKVITKLHNLTPMEILMPDTASVKGQGTKLYSLITETFPSVTFTAVLRRYFNEKKGLEFIQQLCVPEFTT-VLMEVQTKYYCLASASALLKYFEFVQKSIYAPKSLKVTFSGSEQTAMIDAVSASNLELVVNHRNHSEH-TLFGVLNHTKTSGGERRLRSNILEPLLEVDTIKSRQDTIQVI-----FFFSLKFSHTSIAHFLDIDELLSALVQIPK-----------------------------------------FNSIL-----DHIKSLIN----DDTSYMKGSLTMRTQKCYAVRPNVSEFLDIARRAYTEVVDDIAGLVAQLGEKHNLPLRTSFSNARGFFIQMKLEGGAL-PGGKLPDEFIKVSKQKNNFSFTTLDLMKMNDHCEEALKDIFHMSYVVVSKLLNEVHEQIHCLYKLSDVVSMLDMLLSLANACTISNYVRPEFTDTLAIQQGRHPVLERISGQQPISNNSYISEGSNFVIITGPNMSGKSTFLKQVALVQIMAQIGCFVPAEYASVRIADQIFTRIGVDDDFETNSSTFMVEMKEVSYIIHNATNSSLIIIDELGRGTSPEEGIGICHSVCEFLINLKAFTLFATHFLELCQLQTLYPNVENQHMQVQHIRTGDGRAERVVYTYQLSRGHSEERNYGIRAAEMTNLPLDIIQEAKTVADKI 754

[Close]

BLAST of mutS protein homolog 4 vs. Ensembl Zebrafish
Match: msh2 (mutS homolog 2 (E. coli) [Source:ZFIN;Acc:ZDB-GENE-040426-2932])

HSP 1 Score: 196.052 bits (497), Expect = 4.888e-51
Identity = 196/717 (27.34%), Postives = 331/717 (46.16%), Query Frame = 1

Query:  559 IGIASVDLKNPELELSQFSDSIGYSRTLSKLYLKDPVEIVFPHTMCENGVRSKLFQIVSEFMHKSSITTIHRRYYNDKNGKEIIQHL-----CHKDYT-SSILYESREKYYALAACAAIIKYVEFIQNILFAPGSLQIIFSGSVKCAIIDIASVRNLELVE-NSKDLTENGSLFSALNFTTTNGGYRLLRANILQPSFDIPTITSRYDCVEELMNNAELFFTLKSQI-KHFVSLNHLLSLCVQLPKNQTVKSAENTITQVIALKHVMELIPTLRATLQSFKSSLFIE-YHSLLVD-SRYDEILSI---INVVVHEDVHFEKGILQMRSQKLFAIKDGINVILDIARRSYSEQIE-----ALRDEVQALSVEHALPLRVAFSNSRGFYIQLPLTNSSVKPRLSLPFIKVAIVKNFITCTTEKIMKFNERLKGALAEIYLTAELLLSELIKAIRVHMGVLYRLSEISATLDLLLSFAQVSKMQN--YIRPEF----TDTLAIKNCRNPLLDRLSNKEAISNHV-YAANLSNFTIVTGANMSGKSMYLRQIALVQIMGQIGCFIPAEYASFRLSDHLFTRIGVDDDIQSNSSTFTIEMREMSYIINTITDNSLVLIDELGRGTSFDEGLGICFAICEHLL-QTKAFIFIATHFRELSKLEILYPNVQNVNFEVKNLSESDGDENHLLFTYKCVRGVCPDFTNAMKLAKLSNLPKQLLFEA 2631
            +G+  VD    +L + +F D+  +S   + L    P E V P      G   KL Q+V     +  I    R+  ++   K+I+Q L       K  T SS      EK  A++   A+IKY+E + +     GS ++      +   +D A+V+ L L + +S D T   SL   LN   T  G RL+   I QP  D   I  R D VE  + ++EL  + +  + + F  LN +     +   N  ++        V  L +V+  +       Q    + FI   + L+ D S++ E++     +N V H +               F +K   +  L   R +  +++E     AL    + L +E A  +++  +   G++ ++         R +  F  + + KN +  T  K+   NE    +  E       ++ E+I     ++  +  L+E+ A LD ++SFA VS      +IRP+     +  L +K  R+P ++       I N V +      F I+TG NM GKS Y+RQ+ ++ +M QIGCF+P + A   + D +  R+G  D      STF  EM E + I+ + +++SL++IDELGRGTS  +G G+ +AI E++  + K+F   ATHF EL+ L    P V+N++  V  L+     ++ L   YK  +GVC D +  + +A+L++ PK ++  A
Sbjct:  161 VGVGYVDSTLRKLGVCEFPDNDQFSNLEALLVQIGPKECVLP-AGDSGGDLGKLKQVV----QRGGILLTDRKK-SEFTTKDIVQDLNRLLKARKGETVSSAALPEMEKKIAMSCLEAVIKYLELLADEANF-GSFKMTTFDLNQYMRLDNAAVQALNLFQGSSDDATGTHSLAGLLNKCRTPQGQRLVNQWIKQPLIDKNKIEERLDLVETFVEDSELRKSCQEDLLRRFPDLNRMAKKFQRQSSN--LQDCYRVYQSVGQLPNVVLALERYSGKHQVLLHAAFISPLNDLISDFSKFQEMIETTLDMNQVEHHE---------------FLVKPSFDPTLSDLRENM-DRLEKAMQAALSSAARELGLEAAKTVKLESNAQIGYFFRVTCKEEK-SLRNNKKFTTLDVQKNGVRFTNSKLSSLNEEYTKSREEYEEAQNAIVKEIISIAAGYVDPVQTLNEVIAQLDAVVSFAVVSHAAPVPFIRPKILEKGSGRLVLKAARHPCVEAQDEVAFIPNDVTFIRGEKMFHIITGPNMGGKSTYIRQVGVIVLMAQIGCFVPCDEAELSVVDCVLARVGAGDSQIKGVSTFMAEMLETAAILRSASEDSLIIIDELGRGTSTYDGFGLAWAISEYIATRLKSFCLFATHFHELTALAQQVPTVRNLH--VTALTT----DSTLTMLYKVKKGVC-DQSFGIHVAELASFPKHVIANA 844

[Close]

Query:  559 IGIASVDLKNPELELSQFSDSIGYSRTLSKLYLKDPVEIVFPHTMCENGVRSKLFQIVSEFMHKSSITTIHRRYYNDKNGKEIIQHL-----CHKDYT-SSILYESREKYYALAACAAIIKYVEFIQNILFAPGSLQIIFSGSVKCAIIDIASVRNLELVE-NSKDLTENGSLFSALNFTTTNGGYRLLRANILQPSFDIPTITSRYDCVEELMNNAELFFTLKSQI-KHFVSLNHLLSLCVQLPKNQTVKSAENTITQVIALKHVMELIPTLRATLQSFKSSLFIE-YHSLLVD-SRYDEILSI---INVVVHEDVHFEKGILQMRSQKLFAIKDGINVILDIARRSYSEQIE-----ALRDEVQALSVEHALPLRVAFSNSRGFYIQLPLTNSSVKPRLSLPFIKVAIVKNFITCTTEKIMKFNERLKGALAEIYLTAELLLSELIKAIRVHMGVLYRLSEISATLDLLLSFAQVSKMQN--YIRPEF----TDTLAIKNCRNPLLDRLSNKEAISNHV-YAANLSNFTIVTGANMSGKSMYLRQIALVQIMGQIGCFIPAEYASFRLSDHLFTRIGVDDDIQSNSSTFTIEMREMSYIINTITDNSLVLIDELGRGTSFDEGLGICFAICEHLL-QTKAFIFIATHFRELSKLEILYPNVQNVNFEVKNLSESDGDENHLLFTYKCVRGVCPDFTNAMKLAKLSNLPKQLLFEA 2631
            +G+  VD    +L + +F D+  +S   + L    P E V P      G   KL Q+V     +  I    R+  ++   K+I+Q L       K  T SS      EK  A++   A+IKY+E + +     GS ++      +   +D A+V+ L L + +S D T   SL   LN   T  G RL+   I QP  D   I  R D VE  + ++EL  + +  + + F  LN +     +   N  ++        V  L +V+  +       Q    + FI   + L+ D S++ E++     +N V H +               F +K   +  L   R +  +++E     AL    + L +E A  +++  +   G++ ++         R +  F  + + KN +  T  K+   NE    +  E       ++ E+I     ++  +  L+E+ A LD ++SFA VS      +IRP+     +  L +K  R+P ++       I N V +      F I+TG NM GKS Y+RQ+ ++ +M QIGCF+P + A   + D +  R+G  D      STF  EM E + I+ + +++SL++IDELGRGTS  +G G+ +AI E++  + K+F   ATHF EL+ L    P V+N++  V  L+     ++ L   YK  +GVC D +  + +A+L++ PK ++  A
Sbjct:  161 VGVGYVDSTLRKLGVCEFPDNDQFSNLEALLVQIGPKECVLP-AGDSGGDLGKLKQVV----QRGGILLTDRKK-SEFTTKDIVQDLNRLLKARKGETVSSAALPEMEKKIAMSCLEAVIKYLELLADEANF-GSFKMTTFDLNQYMRLDNAAVQALNLFQGSSDDATGTHSLAGLLNKCRTPQGQRLVNQWIKQPLIDKNKIEERLDLVETFVEDSELRKSCQEDLLRRFPDLNRMAKKFQRQSSN--LQDCYRVYQSVGQLPNVVLALERYSGKHQVLLHAAFISPLNDLISDFSKFQEMIETTLDMNQVEHHE---------------FLVKPSFDPTLSDLRENM-DRLEKAMQAALSSAARELGLEAAKTVKLESNAQIGYFFRVTCKEEK-SLRNNKKFTTLDVQKNGVRFTNSKLSSLNEEYTKSREEYEEAQNAIVKEIISIAAGYVDPVQTLNEVIAQLDAVVSFAVVSHAAPVPFIRPKILEKGSGRLVLKAARHPCVEAQDEVAFIPNDVTFIRGEKMFHIITGPNMGGKSTYIRQVGVIVLMAQIGCFVPCDEAELSVVDCVLARVGAGDSQIKGVSTFMAEMLETAAILRSASEDSLIIIDELGRGTSTYDGFGLAWAISEYIATRLKSFCLFATHFHELTALAQQVPTVRNLH--VTALTT----DSTLTMLYKVKKGVC-DQSFGIHVAELASFPKHVIANA 844

[Close]

BLAST of mutS protein homolog 4 vs. Ensembl Xenopus
Match: ak7 (adenylate kinase 7 [Source:Xenbase;Acc:XB-GENE-953547])

HSP 1 Score: 587.8 bits (1514), Expect = 0.000e+0
Identity = 298/690 (43.19%), Postives = 445/690 (64.49%), Query Frame = 1

Query:  526 LIEGRGVASGEIGIASVDLKNPELELSQFSDSIGYSRTLSKLYLKDPVEIVFPHTMCENGVRSKLFQIVSEFMHKSSITTIHRRYYNDKNGKEIIQHLCHKDYTSSILYESREKYYALAACAAIIKYVEFIQNILFAPGSLQIIFSGSVKCAIIDIASVRNLELVENSKDLTENGSLFSALNFTTTNGGYRLLRANILQPSFDIPTITSRYDCVEELMNNAELFFTLKSQIKHFVSLNHLLSLCVQLPKNQTVKSAENTITQVIALKHVMELIPTLRATLQSFKSSLFIEYHSLLVDSRYDEILSIINVVVHEDVHFEKGILQMRSQKLFAIKDGINVILDIARRSYSEQIEALRDEVQALSVEHALPLRVAFSNSRGFYIQLPLTNSSVKPRLSLPFIKVAIVKNFITCTTEKIMKFNERLKGALAEIYLTAELLLSELIKAIRVHMGVLYRLSEISATLDLLLSFAQVSKMQNYIRPEFTDTLAIKNCRNPLLDRLSNKEAISNHVYAANLSNFTIVTGANMSGKSMYLRQIALVQIMGQIGCFIPAEYASFRLSDHLFTRIGVDDDIQSNSSTFTIEMREMSYIINTITDNSLVLIDELGRGTSFDEGLGICFAICEHLLQTKAFIFIATHFRELSKLEILYPNVQNVNFEVKNLSESDGDENHLLFTYKCVRGVCPDFTNAMKLAK 2595
            ++EGRG+A GEIG+AS+DLKNPE+ LSQF+D+  Y + ++KL +  P+EI+ P+T C++G  SKLF +++E     S T + R+Y+N+  G E I+ LC  ++ SS+L E + KYY LAA AA++KYVE+IQN ++AP SL+I F GS K A+ID  S +NLEL+ N +D   + +LF  LN+T T+GG R LR+NIL+P  D+ TI +R DCV+E + + ELFF+L+S +  F+   +LLS  +Q+PK  TV                      L   L++ K+ L   Y++ L D+R+  IL  I  V+++D  + KG L  R+QK +A+K+ IN +LDI RR+Y+E ++ +   +  LS ++ L L+ +F+ +R                         I+KN    TT  ++K NER + +L EIY  + L++ +L+  I  H+  LY+LS+  + LD+LLSFA    + +Y+RPEFTDTLAIK   +P+L++++ ++ +SN+ Y    +NF I+TG NMSGKS YL+QIAL QIM Q+G F+PAEYASF++++ +FTRIG+DDDI++N STF  EM+E++YII    + SL+LIDELGRGTS +EG+GIC+A+CE+LL  KAF    TH+ EL  L  +YPN +N  FEV++  E   D   +L+TY   +G   +    +K A+
Sbjct:   32 VVEGRGLARGEIGMASLDLKNPEVVLSQFADNTIYVKVITKLKILTPLEILMPNTACDSGTASKLFLLIAENFKDVSFTAVQRKYFNETKGLEYIERLCVSEF-SSVLMEVQSKYYCLAAVAALLKYVEYIQNTVYAPKSLKICFQGSEKTAMIDSVSAQNLELLVNKRDSRNDHTLFGVLNYTKTSGGSRRLRSNILEPLVDLKTINTRLDCVQEFLQDEELFFSLQSVLSRFLDTENLLSNLIQIPKQDTVAE--------------------LCVALKNCKTPLLKAYYNSLEDNRFGIILEKIGAVINDDTRYTKGCLSTRTQKCYAVKENINELLDIDRRAYAEIVDDISGLISQLSEKYNLSLKTSFNTARD----------------------ANIIKNSCCFTTVDLLKLNERCQESLKEIYHRSYLIVCKLLSEIYEHIHCLYKLSDTVSMLDMLLSFAHACTLSDYVRPEFTDTLAIKQGWHPILEKIAMEKPVSNNTYITEGNNFVILTGPNMSGKSTYLKQIALNQIMAQLGSFVPAEYASFKIAEQIFTRIGMDDDIETNCSTFMKEMKEVNYIIQNANNKSLILIDELGRGTSTEEGIGICYAVCEYLLGLKAFTLFVTHYLELCHLSTIYPNSENYYFEVQHKREKSEDRESILYTYLLSKGQTKEKNYGLKAAE 678

[Close]

BLAST of mutS protein homolog 4 vs. Ensembl Xenopus
Match: ak7 (adenylate kinase 7 [Source:Xenbase;Acc:XB-GENE-953547])

HSP 1 Score: 273.478 bits (698), Expect = 1.002e-82
Identity = 126/263 (47.91%), Postives = 185/263 (70.34%), Query Frame = 1

Query: 1807 EIYLTAELLLSELIKAIRVHMGVLYRLSEISATLDLLLSFAQVSKMQNYIRPEFTDTLAIKNCRNPLLDRLSNKEAISNHVYAANLSNFTIVTGANMSGKSMYLRQIALVQIMGQIGCFIPAEYASFRLSDHLFTRIGVDDDIQSNSSTFTIEMREMSYIINTITDNSLVLIDELGRGTSFDEGLGICFAICEHLLQTKAFIFIATHFRELSKLEILYPNVQNVNFEVKNLSESDGDENHLLFTYKCVRGVCPDFTNAMKLAK 2595
            ++Y    +++ +L+  I  H+  LY+LS+  + LD+LLSFA    + +Y+RPEFTDTLAIK   +P+L++++ ++ +SN+ Y    +NF I+TG NMSGKS YL+QIAL QIM Q+G F+PAEYASF++++ +FTRIG+DDDI++N STF  EM+E++YII    + SL+LIDELGRGTS +EG+GIC+A+CE+LL  KAF    TH+ EL  L  +YPN +N  FEV++  E   D   +L+TY   +G   +    +K A+
Sbjct:   11 DLYHLYSIIVCKLLSEIYEHIHCLYKLSDTVSMLDMLLSFAHACTLSDYVRPEFTDTLAIKQGWHPILEKIAMEKPVSNNTYITEGNNFVILTGPNMSGKSTYLKQIALNQIMAQLGSFVPAEYASFKIAEQIFTRIGMDDDIETNCSTFMKEMKEVNYIIQNANNKSLILIDELGRGTSTEEGIGICYAVCEYLLGLKAFTLFVTHYLELCHLSTIYPNSENYYFEVQHKREKSEDRESILYTYLLSKGQTKEKNYGLKAAE 273

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BLAST of mutS protein homolog 4 vs. Ensembl Xenopus
Match: MSH2 (mutS homolog 2 [Source:NCBI gene;Acc:100380043])

HSP 1 Score: 194.897 bits (494), Expect = 1.335e-50
Identity = 192/718 (26.74%), Postives = 329/718 (45.82%), Query Frame = 1

Query:  559 IGIASVDLKNPELELSQFSDSIGYSRTLSKLYLKDPVEIVFPHTMCENGVRSKLFQIV------------SEFMHKSSITTIHRRYYNDKNGKEIIQHLCHKDYTSSILYESREKYYALAACAAIIKYVEFIQNILFAPGSLQIIFSGSVKCAIIDIASVRNLELVENS-KDLTENGSLFSALNFTTTNGGYRLLRANILQPSFDIPTITSRYDCVEELMNNAELFFTLKSQI-KHFVSLNHLLSLCVQLPKNQTVKSAENTITQVIALKHVMELIPTLRATLQSFKSSLFIEYHSLLVDSRYDEILSIINVVVHE---DVHFEKGILQMRSQKLFAIKDGINVILDIARRSYSEQIEALRDEVQALSVEHALPLRVAFSNSRGFYIQLPLTNSSVKPRLSLPFIKVAIVKNFITCTTEKIMKFNERLKGALAEIYLTAELLLSELIKAIRVHMGVLYRLSEISATLDLLLSFAQVSKMQN--YIRP----EFTDTLAIKNCRNPLLDRLSNKEAISNHV-YAANLSNFTIVTGANMSGKSMYLRQIALVQIMGQIGCFIPAEYASFRLSDHLFTRIGVDDDIQSNSSTFTIEMREMSYIINTITDNSLVLIDELGRGTSFDEGLGICFAICEHL-LQTKAFIFIATHFRELSKLEILYPNVQNVNFEVKNLSESDGDENHLLFTYKCVRGVCPDFTNAMKLAKLSNLPKQLLFEAEK 2637
            +G+  VD    +L + +F D+  +S   + L    P E V P      G   KL QIV            +EF  K S+  ++R     K G+++         TS+ L E  EK  A++A A+++KY+E + +       +   F  S +   +D A+V  L L   S +D +   SL   LN   T  G RL+   I QP  D   I  R + VE  + +AEL   L+  + + F  LN L     +  + QT       +     L   +  +P +   ++ ++++ F  +     D R  + L ++    HE      F+  + ++R +K+  ++  +   L+ A R               L ++    +++  ++  G + ++         R +  F  + I KN +  T  K+   +E       E       ++ E+I     ++  +  L+++ A LD  +SFA VS      Y+RP    +    + +++ R+P ++   +   I N + +      F I+TG NM GKS Y+RQ  ++ +M QIG F+P + A   + D +  R+G  D      STF  EM E + I+ + T+NSL++IDELGRGTS  +G G+ +AI E++  + KAF   ATHF EL+ L    P V N++  V  L+     E+ L   Y+  RGVC D +  + +A+L+N PK ++  A++
Sbjct:  160 VGVGYVDSTLRKLGVCEFPDNDQFSNLEALLVQIGPKECVMPGGDTA-GDMGKLRQIVKRGGILITDRKKAEFTTKDSVQDLNR-LLKAKKGEQV---------TSAALPE-MEKQVAMSALASVMKYLELLSDESNFGQFVMTNFDLS-QYMKLDNAAVGALNLFPGSAEDTSGTQSLAGLLNKCKTPQGQRLVNQWIKQPLMDKNRIEERLNLVEAFVTDAELRQCLQEDLLRRFPDLNRL----AKKFQRQTA-----NLQDCYRLYQAVNQLPGVIQAIEKYEAASFSAWQ----DQRLSQPLQLVEN--HEFLVKASFDPNLTELR-EKMNELEKNMQAALNGAARE--------------LGLDAGKSIKLESNSQVGHFFRVTCKEEKAL-RNNKKFTTIDIQKNGVRFTNGKLSSLSEEYMRNREEYEEAQNAIVKEIISISAGYVDPIQTLNDVIAQLDAAVSFAYVSNSAPVPYVRPVILEKGQGKIMLQSARHPCIEMQDDVAFIPNDITFEKEKQMFHIITGPNMGGKSTYIRQTGVIVLMAQIGSFVPCDSAEISIVDCILARVGAGDSQLKGVSTFMAEMLETASILRSATENSLIIIDELGRGTSTYDGFGLAWAISEYISTKIKAFCMFATHFHELTALADQVPTVNNLH--VTALT----TEDTLTMLYRIKRGVC-DQSFGIHVAELANFPKHVIETAKE 826

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BLAST of mutS protein homolog 4 vs. Ensembl Xenopus
Match: MSH2 (mutS homolog 2 [Source:NCBI gene;Acc:100380043])

HSP 1 Score: 192.586 bits (488), Expect = 6.160e-50
Identity = 199/730 (27.26%), Postives = 330/730 (45.21%), Query Frame = 1

Query:  559 IGIASVDLKNPELELSQFSDSIGYSRTLSKLYLKDPVEIVFPHTMCENGVRSKLFQIV------------SEFMHKSSITTIHRRYYNDKNGKEIIQHLCHKDYTSSILYESREKYYALAACAAIIKYVEFIQNILFAPGSLQIIFSGSVKCAIIDIASVRNLELVENS-KDLTENGSLFSALNFTTTNGGYRLLRANILQPSFDIPTITSRYDCVEELMNNAELFFTLKSQI-KHFVSLNHL----------LSLCVQLPKNQTVKSAENTITQVIALK--HVMELIPTLRATLQSFKSSLFIEYHSLLVDSRYDEILSIINVVVHE---DVHFEKGILQMRSQKLFAIKDGINVILDIARRSYSEQIEALRDEVQALSVEHALPLRVAFSNSRGFYIQLPLTNSSVKPRLSLPFIKVAIVKNFITCTTEKIMKFNERLKGALAEIYLTAELLLSELIKAIRVHMGVLYRLSEISATLDLLLSFAQVSKMQN--YIRP----EFTDTLAIKNCRNPLLDRLSNKEAISNHV-YAANLSNFTIVTGANMSGKSMYLRQIALVQIMGQIGCFIPAEYASFRLSDHLFTRIGVDDDIQSNSSTFTIEMREMSYIINTITDNSLVLIDELGRGTSFDEGLGICFAICEHL-LQTKAFIFIATHFRELSKLEILYPNVQNVNFEVKNLSESDGDENHLLFTYKCVRGVCPDFTNAMKLAKLSNLPKQLLFEAEK 2637
            +G+  VD    +L + +F D+  +S   + L    P E V P      G   KL QIV            +EF  K S+  ++R     K G+++         TS+ L E  EK  A++A A+++KY+E + +       +   F  S +   +D A+V  L L   S +D +   SL   LN   T  G RL+   I QP  D   I  R + VE  + +AEL   L+  + + F  LN L          L  C +L   Q V      I  +   +  H M L+      L    SS F ++  ++     +  L +  V  HE      F+  + ++R +K+  ++  +   L+ A R               L ++    +++  ++  G + ++         R +  F  + I KN +  T  K+   +E       E       ++ E+I     ++  +  L+++ A LD  +SFA VS      Y+RP    +    + +++ R+P ++   +   I N + +      F I+TG NM GKS Y+RQ  ++ +M QIG F+P + A   + D +  R+G  D      STF  EM E + I+ + T+NSL++IDELGRGTS  +G G+ +AI E++  + KAF   ATHF EL+ L    P V N++  V  L+     E+ L   Y+  RGVC D +  + +A+L+N PK ++  A++
Sbjct:  160 VGVGYVDSTLRKLGVCEFPDNDQFSNLEALLVQIGPKECVMPGGDTA-GDMGKLRQIVKRGGILITDRKKAEFTTKDSVQDLNR-LLKAKKGEQV---------TSAALPE-MEKQVAMSALASVMKYLELLSDESNFGQFVMTNFDLS-QYMKLDNAAVGALNLFPGSAEDTSGTQSLAGLLNKCKTPQGQRLVNQWIKQPLMDKNRIEERLNLVEAFVTDAELRQCLQEDLLRRFPDLNRLAKKFQRQTANLQDCYRL--YQAVNQLPGVIQAIEKYEGTHQMLLLAVFATPLSDL-SSDFSKFQEMI-----ETTLDMDQVENHEFLVKASFDPNLTELR-EKMNELEKNMQAALNGAARE--------------LGLDAGKSIKLESNSQVGHFFRVTCKEEKAL-RNNKKFTTIDIQKNGVRFTNGKLSSLSEEYMRNREEYEEAQNAIVKEIISISAGYVDPIQTLNDVIAQLDAAVSFAYVSNSAPVPYVRPVILEKGQGKIMLQSARHPCIEMQDDVAFIPNDITFEKEKQMFHIITGPNMGGKSTYIRQTGVIVLMAQIGSFVPCDSAEISIVDCILARVGAGDSQLKGVSTFMAEMLETASILRSATENSLIIIDELGRGTSTYDGFGLAWAISEYISTKIKAFCMFATHFHELTALADQVPTVNNLH--VTALTT----EDTLTMLYRIKRGVC-DQSFGIHVAELANFPKHVIETAKE 845

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BLAST of mutS protein homolog 4 vs. Ensembl Xenopus
Match: MSH2 (mutS homolog 2 [Source:NCBI gene;Acc:100380043])

HSP 1 Score: 189.504 bits (480), Expect = 7.354e-49
Identity = 197/731 (26.95%), Postives = 329/731 (45.01%), Query Frame = 1

Query:  559 IGIASVDLKNPELELSQFSDSIGYSRTLSKLYLKDPVEIVFPHTMCENGVRSKLFQI-------------VSEFMHKSSITTIHRRYYNDKNGKEIIQHLCHKDYTSSILYESREKYYALAACAAIIKYVEFIQNILFAPGSLQIIFSGSVKCAIIDIASVRNLELVENS-KDLTENGSLFSALNFTTTNGGYRLLRANILQPSFDIPTITSRYDCVEELMNNAELFFTLKSQI-KHFVSLNHL----------LSLCVQLPKNQTVKSAENTITQVIALK--HVMELIPTLRATLQSFKSSLFIEYHSLLVDSRYDEILSIINVVVHE---DVHFEKGILQMRSQKLFAIKDGINVILDIARRSYSEQIEALRDEVQALSVEHALPLRVAFSNSRGFYIQLPLTNSSVKPRLSLPFIKVAIVKNFITCTTEKIMKFNERLKGALAEIYLTAELLLSELIKAIRVHMGVLYRLSEISATLDLLLSFAQVSKMQN--YIRP----EFTDTLAIKNCRNPLLDRLSNKEAISNHV-YAANLSNFTIVTGANMSGKSMYLRQIALVQIMGQIGCFIPAEYASFRLSDHLFTRIGVDDDIQSNSSTFTIEMREMSYIINTITDNSLVLIDELGRGTSFDEGLGICFAICEHL-LQTKAFIFIATHFRELSKLEILYPNVQNVNFEVKNLSESDGDENHLLFTYKCVRGVCPDFTNAMKLAKLSNLPKQLLFEAEK 2637
            +G+  VD    +L + +F D+  +S   + L    P E V P      G   KL Q+              +EF  K S+  ++R     K G+++         TS+ L E  EK  A++A A+++KY+E + +       +   F  S +   +D A+V  L L   S +D +   SL   LN   T  G RL+   I QP  D   I  R + VE  + +AEL   L+  + + F  LN L          L  C +L   Q V      I  +   +  H M L+      L    SS F ++  ++     +  L +  V  HE      F+  + ++R +K+  ++  +   L+ A R               L ++    +++  ++  G + ++         R +  F  + I KN +  T  K+   +E       E       ++ E+I     ++  +  L+++ A LD  +SFA VS      Y+RP    +    + +++ R+P ++   +   I N + +      F I+TG NM GKS Y+RQ  ++ +M QIG F+P + A   + D +  R+G  D      STF  EM E + I+ + T+NSL++IDELGRGTS  +G G+ +AI E++  + KAF   ATHF EL+ L    P V N++  V  L+     E+ L   Y+  RGVC D +  + +A+L+N PK ++  A++
Sbjct:  160 VGVGYVDSTLRKLGVCEFPDNDQFSNLEALLVQIGPKECVMPGGDTA-GDMGKLRQVRDSRGGILITDRKKAEFTTKDSVQDLNR-LLKAKKGEQV---------TSAALPE-MEKQVAMSALASVMKYLELLSDESNFGQFVMTNFDLS-QYMKLDNAAVGALNLFPGSAEDTSGTQSLAGLLNKCKTPQGQRLVNQWIKQPLMDKNRIEERLNLVEAFVTDAELRQCLQEDLLRRFPDLNRLAKKFQRQTANLQDCYRL--YQAVNQLPGVIQAIEKYEGTHQMLLLAVFATPLSDL-SSDFSKFQEMI-----ETTLDMDQVENHEFLVKASFDPNLTELR-EKMNELEKNMQAALNGAARE--------------LGLDAGKSIKLESNSQVGHFFRVTCKEEKAL-RNNKKFTTIDIQKNGVRFTNGKLSSLSEEYMRNREEYEEAQNAIVKEIISISAGYVDPIQTLNDVIAQLDAAVSFAYVSNSAPVPYVRPVILEKGQGKIMLQSARHPCIEMQDDVAFIPNDITFEKEKQMFHIITGPNMGGKSTYIRQTGVIVLMAQIGSFVPCDSAEISIVDCILARVGAGDSQLKGVSTFMAEMLETASILRSATENSLIIIDELGRGTSTYDGFGLAWAISEYISTKIKAFCMFATHFHELTALADQVPTVNNLH--VTALTT----EDTLTMLYRIKRGVC-DQSFGIHVAELANFPKHVIETAKE 846

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BLAST of mutS protein homolog 4 vs. Ensembl Mouse
Match: Msh4 (mutS homolog 4 [Source:MGI Symbol;Acc:MGI:1860077])

HSP 1 Score: 654.44 bits (1687), Expect = 0.000e+0
Identity = 328/742 (44.20%), Postives = 504/742 (67.92%), Query Frame = 1

Query:  526 LIEGRGVASGEIGIASVDLKNPELELSQFSDSIGYSRTLSKLYLKDPVEIVFPHTMCENGVRSKLFQIVSEFMHKSSITTIHRRYYNDKNGKEIIQHLCHKDYTSSILYESREKYYALAACAAIIKYVEFIQNILFAPGSLQIIFSGSVKCAIIDIASVRNLELVENSKDLTENGSLFSALNFTTTNGGYRLLRANILQPSFDIPTITSRYDCVEELMNNAELFFTLKSQIKHFVSLNHLLSLCVQLPKNQTVKSAENTITQVIALKHVMELIPTLRATLQSFKSSLFIEYHSLLVDSRYDEILSIINVVVHEDVHFEKGILQMRSQKLFAIKDGINVILDIARRSYSEQIEALRDEVQALSVEHALPLRVAFSNSRGFYIQLPLTNSSVKPRLSLP--FIKVAIVKNFITCTTEKIMKFNERLKGALAEIYLTAELLLSELIKAIRVHMGVLYRLSEISATLDLLLSFAQVSKMQNYIRPEFTDTLAIKNCRNPLLDRLSNKEAISNHVYAANLSNFTIVTGANMSGKSMYLRQIALVQIMGQIGCFIPAEYASFRLSDHLFTRIGVDDDIQSNSSTFTIEMREMSYIINTITDNSLVLIDELGRGTSFDEGLGICFAICEHLLQTKAFIFIATHFRELSKLEILYPNVQNVNFEVKNLSESDGDENHLLFTYKCVRGVCPDFTNAMKLAKLSNLPKQLLFEAEKIYGRLGDSNELIIEVKSQFIRNIHKGRPLGKERGVF 2745
            ++EGRG+A GEIG+AS+DLK+P++ LSQF+D+  Y++ ++KL +  P+EI+  +T C  G  +KLF +++E     + TT+ R+Y+N+  G E I+ LC  ++ SS+L E + +YY LAA AA++KYVEFIQN ++AP SL+I F GS + A+ID +S +NLEL+ N++D   N +LF  LN+T T GG R LR+NIL+P  D+ TI+ R DCV+EL+ + ELFF L+S I  F+    LLS+ VQ+PK  TV +AE+ IT +I LKH +EL+  L+ TL++  + L   Y+  L D R+  IL  I  V+++D  + KG L MR+QK +A++  I+  LDIARR+Y+E ++ +   +  L+ +++LPLR +FS+SRGF+IQ+  T+ +      LP  FIK++ VKN  + T+  ++K NER + +L EIY    +++ +L+  I  H+  LY+LS+  + LD+LLSFA    + +Y+RPEFTDTLAIK   +P+L+++S ++ ++N+ Y    SN  I+TG NMSGKS YL+QIAL QIM QIG ++PAEYASFR++  +FTRI  DDDI++NSSTF  EM+E++YI++   D SL+LIDELGRGT+ +EG+GI +A+CEHLL  KAF    THF EL  L+ LY NV+N++FEV+++  +  +++ +L+TYK  RG+  +    +K A+ S+LP  ++           D+ ++  ++  Q ++N      + ++R V+
Sbjct:   94 VVEGRGLARGEIGMASIDLKSPQIMLSQFADNTTYAKVITKLQVLSPLEIIMSNTACVVGNSTKLFTLITENFKNVNFTTVQRKYFNETKGLEYIEQLCIAEF-SSVLMEVQSRYYCLAAAAALLKYVEFIQNSVYAPKSLKIYFQGSEQTAMIDSSSAQNLELLVNNQDYRSNHTLFGVLNYTKTAGGSRRLRSNILEPLVDVETISMRLDCVQELLQDEELFFGLQSVISRFLDTEQLLSVLVQIPKQDTVNAAESKITNLIYLKHTLELVEPLKVTLKNCSTPLLRAYYGSLEDHRFGLILDKIKTVINDDARYMKGCLNMRTQKCYAVRSNISEFLDIARRTYTEIVDDIAGMIAQLAEKYSLPLRTSFSSSRGFFIQMT-TDCAALSSDQLPSEFIKISKVKNSYSFTSADLIKMNERCQESLREIYHMTYMIVCKLLSEIYEHIHCLYKLSDTVSMLDMLLSFAHACTLSDYVRPEFTDTLAIKQGWHPILEKISAEKPVANNTYITEGSNVLIITGPNMSGKSTYLKQIALCQIMAQIGSYVPAEYASFRIAAQIFTRISTDDDIETNSSTFMKEMKEIAYILHNANDKSLILIDELGRGTNTEEGIGISYAVCEHLLSIKAFTLFTTHFLELCHLDALYLNVENMHFEVQHVKNTSRNKDAILYTYKLSRGLTEEKNYGLKAAEASSLPSSIVL----------DARDITTQITRQILQNQRSSPEMDRQRAVY 823

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Query:  526 LIEGRGVASGEIGIASVDLKNPELELSQFSDSIGYSRTLSKLYLKDPVEIVFPHTMCENGVRSKLFQIVSEFMHKSSITTIHRRYYNDKNGKEIIQHLCHKDYTSSILYESREKYYALAACAAIIKYVEFIQNILFAPGSLQIIFSGSVKCAIIDIASVRNLELVENSKDLTENGSLFSALNFTTTNGGYRLLRANILQPSFDIPTITSRYDCVEELMNNAELFFTLKSQIKHFVSLNHLLSLCVQLPKNQTVKSAENTITQVIALKHVMELIPTLRATLQSFKSSLFIEYHSLLVDSRYDEILSIINVVVHEDVHFEKGILQMRSQKLFAIKDGINVILDIARRSYSEQIEALRDEVQALSVEHALPLRVAFSNSRGFYIQLPLTNSSVKPRLSLP--FIKVAIVKNFITCTTEKIMKFNERLKGALAEIYLTAELLLSELIKAIRVHMGVLYRLSEISATLDLLLSFAQVSKMQNYIRPEFTDTLAIKNCRNPLLDRLSNKEAISNHVYAANLSNFTIVTGANMSGKSMYLRQIALVQIMGQIGCFIPAEYASFRLSDHLFTRIGVDDDIQSNSSTFTIEMREMSYIINTITDNSLVLIDELGRGTSFDEGLGICFAICEHLLQTKAFIFIATHFRELSKLEILYPNVQNVNFEVKNLSESDGDENHLLFTYKCVRGVCPDFTNAMKLAKLSNLPKQLLFEAEKIYGRLGDSNELIIEVKSQFIRNIHKGRPLGKERGVF 2745
            ++EGRG+A GEIG+AS+DLK+P++ LSQF+D+  Y++ ++KL +  P+EI+  +T C  G  +KLF +++E     + TT+ R+Y+N+  G E I+ LC  ++ SS+L E + +YY LAA AA++KYVEFIQN ++AP SL+I F GS + A+ID +S +NLEL+ N++D   N +LF  LN+T T GG R LR+NIL+P  D+ TI+ R DCV+EL+ + ELFF L+S I  F+    LLS+ VQ+PK  TV +AE+ IT +I LKH +EL+  L+ TL++  + L   Y+  L D R+  IL  I  V+++D  + KG L MR+QK +A++  I+  LDIARR+Y+E ++ +   +  L+ +++LPLR +FS+SRGF+IQ+  T+ +      LP  FIK++ VKN  + T+  ++K NER + +L EIY    +++ +L+  I  H+  LY+LS+  + LD+LLSFA    + +Y+RPEFTDTLAIK   +P+L+++S ++ ++N+ Y    SN  I+TG NMSGKS YL+QIAL QIM QIG ++PAEYASFR++  +FTRI  DDDI++NSSTF  EM+E++YI++   D SL+LIDELGRGT+ +EG+GI +A+CEHLL  KAF    THF EL  L+ LY NV+N++FEV+++  +  +++ +L+TYK  RG+  +    +K A+ S+LP  ++           D+ ++  ++  Q ++N      + ++R V+
Sbjct:  182 VVEGRGLARGEIGMASIDLKSPQIMLSQFADNTTYAKVITKLQVLSPLEIIMSNTACVVGNSTKLFTLITENFKNVNFTTVQRKYFNETKGLEYIEQLCIAEF-SSVLMEVQSRYYCLAAAAALLKYVEFIQNSVYAPKSLKIYFQGSEQTAMIDSSSAQNLELLVNNQDYRSNHTLFGVLNYTKTAGGSRRLRSNILEPLVDVETISMRLDCVQELLQDEELFFGLQSVISRFLDTEQLLSVLVQIPKQDTVNAAESKITNLIYLKHTLELVEPLKVTLKNCSTPLLRAYYGSLEDHRFGLILDKIKTVINDDARYMKGCLNMRTQKCYAVRSNISEFLDIARRTYTEIVDDIAGMIAQLAEKYSLPLRTSFSSSRGFFIQM-TTDCAALSSDQLPSEFIKISKVKNSYSFTSADLIKMNERCQESLREIYHMTYMIVCKLLSEIYEHIHCLYKLSDTVSMLDMLLSFAHACTLSDYVRPEFTDTLAIKQGWHPILEKISAEKPVANNTYITEGSNVLIITGPNMSGKSTYLKQIALCQIMAQIGSYVPAEYASFRIAAQIFTRISTDDDIETNSSTFMKEMKEIAYILHNANDKSLILIDELGRGTNTEEGIGISYAVCEHLLSIKAFTLFTTHFLELCHLDALYLNVENMHFEVQHVKNTSRNKDAILYTYKLSRGLTEEKNYGLKAAEASSLPSSIVL----------DARDITTQITRQILQNQRSSPEMDRQRAVY 911

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BLAST of mutS protein homolog 4 vs. Ensembl Mouse
Match: Msh4 (mutS homolog 4 [Source:MGI Symbol;Acc:MGI:1860077])

HSP 1 Score: 632.098 bits (1629), Expect = 0.000e+0
Identity = 319/729 (43.76%), Postives = 492/729 (67.49%), Query Frame = 1

Query:  565 IASVDLKNPELELSQFSDSIGYSRTLSKLYLKDPVEIVFPHTMCENGVRSKLFQIVSEFMHKSSITTIHRRYYNDKNGKEIIQHLCHKDYTSSILYESREKYYALAACAAIIKYVEFIQNILFAPGSLQIIFSGSVKCAIIDIASVRNLELVENSKDLTENGSLFSALNFTTTNGGYRLLRANILQPSFDIPTITSRYDCVEELMNNAELFFTLKSQIKHFVSLNHLLSLCVQLPKNQTVKSAENTITQVIALKHVMELIPTLRATLQSFKSSLFIEYHSLLVDSRYDEILSIINVVVHEDVHFEKGILQMRSQKLFAIKDGINVILDIARRSYSEQIEALRDEVQALSVEHALPLRVAFSNSRGFYIQLPLTNSSVKPRLSLP--FIKVAIVKNFITCTTEKIMKFNERLKGALAEIYLTAELLLSELIKAIRVHMGVLYRLSEISATLDLLLSFAQVSKMQNYIRPEFTDTLAIKNCRNPLLDRLSNKEAISNHVYAANLSNFTIVTGANMSGKSMYLRQIALVQIMGQIGCFIPAEYASFRLSDHLFTRIGVDDDIQSNSSTFTIEMREMSYIINTITDNSLVLIDELGRGTSFDEGLGICFAICEHLLQTKAFIFIATHFRELSKLEILYPNVQNVNFEVKNLSESDGDENHLLFTYKCVRGVCPDFTNAMKLAKLSNLPKQLLFEAEKIYGRLGDSNELIIEVKSQFIRNIHKGRPLGKERGVF 2745
            +AS+DLK+P++ LSQF+D+  Y++ ++KL +  P+EI+  +T C  G  +KLF +++E     + TT+ R+Y+N+  G E I+ LC  ++ SS+L E + +YY LAA AA++KYVEFIQN ++AP SL+I F GS + A+ID +S +NLEL+ N++D   N +LF  LN+T T GG R LR+NIL+P  D+ TI+ R DCV+EL+ + ELFF L+S I  F+    LLS+ VQ+PK  TV +AE+ IT +I LKH +EL+  L+ TL++  + L   Y+  L D R+  IL  I  V+++D  + KG L MR+QK +A++  I+  LDIARR+Y+E ++ +   +  L+ +++LPLR +FS+SRGF+IQ+  T+ +      LP  FIK++ VKN  + T+  ++K NER + +L EIY    +++ +L+  I  H+  LY+LS+  + LD+LLSFA    + +Y+RPEFTDTLAIK   +P+L+++S ++ ++N+ Y    SN  I+TG NMSGKS YL+QIAL QIM QIG ++PAEYASFR++  +FTRI  DDDI++NSSTF  EM+E++YI++   D SL+LIDELGRGT+ +EG+GI +A+CEHLL  KAF    THF EL  L+ LY NV+N++FEV+++  +  +++ +L+TYK  RG+  +    +K A+ S+LP  ++           D+ ++  ++  Q ++N      + ++R V+
Sbjct:    1 MASIDLKSPQIMLSQFADNTTYAKVITKLQVLSPLEIIMSNTACVVGNSTKLFTLITENFKNVNFTTVQRKYFNETKGLEYIEQLCIAEF-SSVLMEVQSRYYCLAAAAALLKYVEFIQNSVYAPKSLKIYFQGSEQTAMIDSSSAQNLELLVNNQDYRSNHTLFGVLNYTKTAGGSRRLRSNILEPLVDVETISMRLDCVQELLQDEELFFGLQSVISRFLDTEQLLSVLVQIPKQDTVNAAESKITNLIYLKHTLELVEPLKVTLKNCSTPLLRAYYGSLEDHRFGLILDKIKTVINDDARYMKGCLNMRTQKCYAVRSNISEFLDIARRTYTEIVDDIAGMIAQLAEKYSLPLRTSFSSSRGFFIQMT-TDCAALSSDQLPSEFIKISKVKNSYSFTSADLIKMNERCQESLREIYHMTYMIVCKLLSEIYEHIHCLYKLSDTVSMLDMLLSFAHACTLSDYVRPEFTDTLAIKQGWHPILEKISAEKPVANNTYITEGSNVLIITGPNMSGKSTYLKQIALCQIMAQIGSYVPAEYASFRIAAQIFTRISTDDDIETNSSTFMKEMKEIAYILHNANDKSLILIDELGRGTNTEEGIGISYAVCEHLLSIKAFTLFTTHFLELCHLDALYLNVENMHFEVQHVKNTSRNKDAILYTYKLSRGLTEEKNYGLKAAEASSLPSSIVL----------DARDITTQITRQILQNQRSSPEMDRQRAVY 717

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BLAST of mutS protein homolog 4 vs. Ensembl Mouse
Match: Msh3 (mutS homolog 3 [Source:MGI Symbol;Acc:MGI:109519])

HSP 1 Score: 194.897 bits (494), Expect = 2.361e-50
Identity = 169/607 (27.84%), Postives = 301/607 (49.59%), Query Frame = 1

Query:  877 LAACAAIIKYV-EF-IQNILFAPGSLQIIFSGSVKCAIIDIASVRNLELVENSKDLTENGSLFSALNFTTTNGGYRLLRANILQPSFDIPTITSRYDCVEELMNN-AELFFTLKSQIKHFVSLNHLLSLCVQLPKNQTVKSAENTITQVIALKHVME-LIPTLRATLQS-FKSSLFIEYHSLLVDSRYDEILSIINVVVHEDVHFEKGILQMRSQKLFAIKDGINVILDIARRS-YSEQIEALRDEVQALSVEHALP-LRVAFSNSRGFYIQLPLTNSSVKPRLSLPFIKVAIVKNFITCTTEKIMKFNERLKGALAEIYLTAELLLSELIKAIRVHMGVLYRLSEISATLDLLLSFAQVSKMQNYIRPEFTD--TLAIKNCRNPLLDRL--SNKEAISNHVYAANLSNFTIVTGANMSGKSMYLRQIALVQIMGQIGCFIPAEYASFRLSDHLFTRIGVDDDIQSNSSTFTIEMREMSYIINTITDNSLVLIDELGRGTSFDEGLGICFAICEHLLQ-TKAFIFIATHFRELSKLEILYPNVQNVNFEVKNLSESD------GD----ENHLLFTYKCVRGVCPDFTNAMKLAKLSNLPKQLLFEA 2631
            + A AA+I+Y+ EF ++ +L  P S + + SG ++   I+  ++RNLE+++N  D+   GSL   L+ T T+ G R L+  + QP   +  I +R D V +++++ + +F  +++ ++    +     LC    K  + +     +  +  LK  ++ L+P + + +QS    +L +E   LL  S  +  L ++N           G       K    KD  +  L   R++   E I +++  +Q       LP L+    + + F I++   NS+V   +   ++KV   K         I++   RL     ++ L         ++    H   L +  +  AT+D + S A+V+K  NY RP   +   + IKN R+P++D L     + + N    ++     I+TG NM GKS Y++Q+ALV IM QIG ++PAE A+  + D +FTR+G  D+I    STF  E+ + + II   +  SLV++DELGRGTS  +G+ I +A  E+ ++  K+     TH+  + +LE  YP  Q  N+ +  L   D      GD     + + F Y+  RG+    +  + +AKL+++P+++L +A
Sbjct:  458 ICALAAVIRYLKEFNLEKMLSKPESFKQLSSG-MEFMRINGTTLRNLEILQNQTDMKTKGSLLWVLDHTKTSFGRRKLKNWVTQPLLKLREINARLDAVSDVLHSESSVFEQIENLLRKLPDVER--GLCSIYHKKCSTQEFFLIVKSLCQLKSELQALMPAVNSHVQSDLLRALIVEAPELL--SPVEHYLKVLN-----------GPAAKVGDKTELFKDLSDFPLIKKRKNEIQEVIHSIQMRLQEFRKILKLPSLQYVTVSGQEFMIEI--KNSAVSC-IPADWVKVGSTKAVSRFHPPFIVESYRRLNQLREQLVLDCNAEWLGFLENFGEHYHTLCKAVDHLATVDCIFSLAKVAKQGNYCRPTLQEEKKIIIKNGRHPMIDVLLGEQDQFVPNSTSLSDSERVMIITGPNMGGKSSYIKQVALVTIMAQIGSYVPAEEATIGIVDGIFTRMGAADNIYKGRSTFMEELTDTAEIIRRASPQSLVILDELGRGTSTHDGIAIAYATLEYFIRDVKSLTLFVTHYPPVCELEKCYPE-QVGNYHMGFLVNEDESKQDSGDMEQMPDSVTFLYQITRGIAAR-SYGLNVAKLADVPREVLQKA 1043

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BLAST of mutS protein homolog 4 vs. Ensembl Mouse
Match: Msh3 (mutS homolog 3 [Source:MGI Symbol;Acc:MGI:109519])

HSP 1 Score: 191.045 bits (484), Expect = 3.309e-49
Identity = 170/608 (27.96%), Postives = 301/608 (49.51%), Query Frame = 1

Query:  877 LAACAAIIKYV-EF-IQNILFAPGSLQIIFSGSVKCAIIDIASVRNLELVENSKDLTENGSLFSALNFTTTNGGYRLLRANILQPSFDIPTITSRYDCVEELMNN-AELFFTLKSQIKHFVSLNHLLSLCVQLPKNQTVKSAENTITQVIALKHVME-LIPTLRATLQS-FKSSLFIEYHSLLVDSRYDEILSIINVVVHEDVHFEKGILQMRSQKLFAIKDGINVILDIARRS-YSEQIEALRDEVQALSVEHALP-LRVAFSNSRGFYIQLPLTNSSVKPRLSLPFIKVAIVKNFITCTTEKIMKFNERLKGALAEIYLTAELLLSELIKAIRVHMGVLYRLSEISATLDLLLSFAQVSKMQNYIRPEFTD--TLAIKNCRNPLLDRL--SNKEAISNHVYAANLSN-FTIVTGANMSGKSMYLRQIALVQIMGQIGCFIPAEYASFRLSDHLFTRIGVDDDIQSNSSTFTIEMREMSYIINTITDNSLVLIDELGRGTSFDEGLGICFAICEHLLQ-TKAFIFIATHFRELSKLEILYPNVQNVNFEVKNLSESD------GD----ENHLLFTYKCVRGVCPDFTNAMKLAKLSNLPKQLLFEA 2631
            + A AA+I+Y+ EF ++ +L  P S + + SG ++   I+  ++RNLE+++N  D+   GSL   L+ T T+ G R L+  + QP   +  I +R D V +++++ + +F  +++ ++    +     LC    K  + +     +  +  LK  ++ L+P + + +QS    +L +E   LL  S  +  L ++N           G       K    KD  +  L   R++   E I +++  +Q       LP L+    + + F I++   NS+V   +   ++KV   K         I++   RL     ++ L         ++    H   L +  +  AT+D + S A+V+K  NY RP   +   + IKN R+P++D L     + + N    +  S    I+TG NM GKS Y++Q+ALV IM QIG ++PAE A+  + D +FTR+G  D+I    STF  E+ + + II   +  SLV++DELGRGTS  +G+ I +A  E+ ++  K+     TH+  + +LE  YP  Q  N+ +  L   D      GD     + + F Y+  RG+    +  + +AKL+++P+++L +A
Sbjct:  458 ICALAAVIRYLKEFNLEKMLSKPESFKQLSSG-MEFMRINGTTLRNLEILQNQTDMKTKGSLLWVLDHTKTSFGRRKLKNWVTQPLLKLREINARLDAVSDVLHSESSVFEQIENLLRKLPDVER--GLCSIYHKKCSTQEFFLIVKSLCQLKSELQALMPAVNSHVQSDLLRALIVEAPELL--SPVEHYLKVLN-----------GPAAKVGDKTELFKDLSDFPLIKKRKNEIQEVIHSIQMRLQEFRKILKLPSLQYVTVSGQEFMIEI--KNSAVSC-IPADWVKVGSTKAVSRFHPPFIVESYRRLNQLREQLVLDCNAEWLGFLENFGEHYHTLCKAVDHLATVDCIFSLAKVAKQGNYCRPTLQEEKKIIIKNGRHPMIDVLLGEQDQFVPNSTSLSQDSERVMIITGPNMGGKSSYIKQVALVTIMAQIGSYVPAEEATIGIVDGIFTRMGAADNIYKGRSTFMEELTDTAEIIRRASPQSLVILDELGRGTSTHDGIAIAYATLEYFIRDVKSLTLFVTHYPPVCELEKCYPE-QVGNYHMGFLVNEDESKQDSGDMEQMPDSVTFLYQITRGIAAR-SYGLNVAKLADVPREVLQKA 1044

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BLAST of mutS protein homolog 4 vs. UniProt/SwissProt
Match: sp|O15457|MSH4_HUMAN (MutS protein homolog 4 OS=Homo sapiens OX=9606 GN=MSH4 PE=1 SV=2)

HSP 1 Score: 677.552 bits (1747), Expect = 0.000e+0
Identity = 332/742 (44.74%), Postives = 505/742 (68.06%), Query Frame = 1

Query:  526 LIEGRGVASGEIGIASVDLKNPELELSQFSDSIGYSRTLSKLYLKDPVEIVFPHTMCENGVRSKLFQIVSEFMHKSSITTIHRRYYNDKNGKEIIQHLCHKDYTSSILYESREKYYALAACAAIIKYVEFIQNILFAPGSLQIIFSGSVKCAIIDIASVRNLELVENSKDLTENGSLFSALNFTTTNGGYRLLRANILQPSFDIPTITSRYDCVEELMNNAELFFTLKSQIKHFVSLNHLLSLCVQLPKNQTVKSAENTITQVIALKHVMELIPTLRATLQSFKSSLFIEYHSLLVDSRYDEILSIINVVVHEDVHFEKGILQMRSQKLFAIKDGINVILDIARRSYSEQIEALRDEVQALSVEHALPLRVAFSNSRGFYIQLPLTNSSVKPRLSLP--FIKVAIVKNFITCTTEKIMKFNERLKGALAEIYLTAELLLSELIKAIRVHMGVLYRLSEISATLDLLLSFAQVSKMQNYIRPEFTDTLAIKNCRNPLLDRLSNKEAISNHVYAANLSNFTIVTGANMSGKSMYLRQIALVQIMGQIGCFIPAEYASFRLSDHLFTRIGVDDDIQSNSSTFTIEMREMSYIINTITDNSLVLIDELGRGTSFDEGLGICFAICEHLLQTKAFIFIATHFRELSKLEILYPNVQNVNFEVKNLSESDGDENHLLFTYKCVRGVCPDFTNAMKLAKLSNLPKQLLFEAEKIYGRLGDSNELIIEVKSQFIRNIHKGRPLGKERGVF 2745
            ++EGRG+A GEIG+AS+DLKNP++ LSQF+D+  Y++ ++KL +  P+EI+  +T C  G  +KLF +++E     + TTI R+Y+N+  G E I+ LC  ++ S++L E + KYY LAA AA++KYVEFIQN ++AP SL+I F GS + A+ID +S +NLEL+ N++D   N +LF  LN+T T GG R LR+NIL+P  DI TI  R DCV+EL+ + ELFF L+S I  F+    LLS+ VQ+PK  TV +AE+ IT +I LKH +EL+  L+  +++  + L   Y+  L D R+  IL  I  V+++D  + KG L MR+QK +A++  IN  LDIARR+Y+E ++ +   +  L  +++LPLR +FS++RGF+IQ+  T+    P   LP  FIK++ VKN  + T+  ++K NER + +L EIY    +++ +L+  I  H+  LY+LS+  + LD+LLSFA    + +Y+RPEFTDTLAIK   +P+L+++S ++ I+N+ Y    SNF I+TG NMSGKS YL+QIAL QIM QIG ++PAEY+SFR++  +FTRI  DDDI++NSSTF  EM+E++YI++   D SL+LIDELGRGT+ +EG+GIC+A+CE+LL  KAF   ATHF EL  ++ LYPNV+N++FEV+++  +  ++  +L+TYK  +G+  +    +K A++S+LP  ++           D+ E+  ++  Q ++N      + ++R V+
Sbjct:  160 VVEGRGLARGEIGMASIDLKNPQIILSQFADNTTYAKVITKLKILSPLEIIMSNTACAVGNSTKLFTLITENFKNVNFTTIQRKYFNETKGLEYIEQLCIAEF-STVLMEVQSKYYCLAAVAALLKYVEFIQNSVYAPKSLKICFQGSEQTAMIDSSSAQNLELLINNQDYRNNHTLFGVLNYTKTPGGSRRLRSNILEPLVDIETINMRLDCVQELLQDEELFFGLQSVISRFLDTEQLLSVLVQIPKQDTVNAAESKITNLIYLKHTLELVDPLKIAMKNCNTPLLRAYYGSLEDKRFGIILEKIKTVINDDARYMKGCLNMRTQKCYAVRSNINEFLDIARRTYTEIVDDIAGMISQLGEKYSLPLRTSFSSARGFFIQM-TTDCIALPSDQLPSEFIKISKVKNSYSFTSADLIKMNERCQESLREIYHMTYMIVCKLLSEIYEHIHCLYKLSDTVSMLDMLLSFAHACTLSDYVRPEFTDTLAIKQGWHPILEKISAEKPIANNTYVTEGSNFLIITGPNMSGKSTYLKQIALCQIMAQIGSYVPAEYSSFRIAKQIFTRISTDDDIETNSSTFMKEMKEIAYILHNANDKSLILIDELGRGTNTEEGIGICYAVCEYLLSLKAFTLFATHFLELCHIDALYPNVENMHFEVQHVKNTSRNKEAILYTYKLSKGLTEEKNYGLKAAEVSSLPPSIVL----------DAKEITTQITRQILQNQRSTPEMERQRAVY 889

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BLAST of mutS protein homolog 4 vs. UniProt/SwissProt
Match: sp|Q99MT2|MSH4_MOUSE (MutS protein homolog 4 OS=Mus musculus OX=10090 GN=Msh4 PE=2 SV=1)

HSP 1 Score: 654.44 bits (1687), Expect = 0.000e+0
Identity = 328/742 (44.20%), Postives = 504/742 (67.92%), Query Frame = 1

Query:  526 LIEGRGVASGEIGIASVDLKNPELELSQFSDSIGYSRTLSKLYLKDPVEIVFPHTMCENGVRSKLFQIVSEFMHKSSITTIHRRYYNDKNGKEIIQHLCHKDYTSSILYESREKYYALAACAAIIKYVEFIQNILFAPGSLQIIFSGSVKCAIIDIASVRNLELVENSKDLTENGSLFSALNFTTTNGGYRLLRANILQPSFDIPTITSRYDCVEELMNNAELFFTLKSQIKHFVSLNHLLSLCVQLPKNQTVKSAENTITQVIALKHVMELIPTLRATLQSFKSSLFIEYHSLLVDSRYDEILSIINVVVHEDVHFEKGILQMRSQKLFAIKDGINVILDIARRSYSEQIEALRDEVQALSVEHALPLRVAFSNSRGFYIQLPLTNSSVKPRLSLP--FIKVAIVKNFITCTTEKIMKFNERLKGALAEIYLTAELLLSELIKAIRVHMGVLYRLSEISATLDLLLSFAQVSKMQNYIRPEFTDTLAIKNCRNPLLDRLSNKEAISNHVYAANLSNFTIVTGANMSGKSMYLRQIALVQIMGQIGCFIPAEYASFRLSDHLFTRIGVDDDIQSNSSTFTIEMREMSYIINTITDNSLVLIDELGRGTSFDEGLGICFAICEHLLQTKAFIFIATHFRELSKLEILYPNVQNVNFEVKNLSESDGDENHLLFTYKCVRGVCPDFTNAMKLAKLSNLPKQLLFEAEKIYGRLGDSNELIIEVKSQFIRNIHKGRPLGKERGVF 2745
            ++EGRG+A GEIG+AS+DLK+P++ LSQF+D+  Y++ ++KL +  P+EI+  +T C  G  +KLF +++E     + TT+ R+Y+N+  G E I+ LC  ++ SS+L E + +YY LAA AA++KYVEFIQN ++AP SL+I F GS + A+ID +S +NLEL+ N++D   N +LF  LN+T T GG R LR+NIL+P  D+ TI+ R DCV+EL+ + ELFF L+S I  F+    LLS+ VQ+PK  TV +AE+ IT +I LKH +EL+  L+ TL++  + L   Y+  L D R+  IL  I  V+++D  + KG L MR+QK +A++  I+  LDIARR+Y+E ++ +   +  L+ +++LPLR +FS+SRGF+IQ+  T+ +      LP  FIK++ VKN  + T+  ++K NER + +L EIY    +++ +L+  I  H+  LY+LS+  + LD+LLSFA    + +Y+RPEFTDTLAIK   +P+L+++S ++ ++N+ Y    SN  I+TG NMSGKS YL+QIAL QIM QIG ++PAEYASFR++  +FTRI  DDDI++NSSTF  EM+E++YI++   D SL+LIDELGRGT+ +EG+GI +A+CEHLL  KAF    THF EL  L+ LY NV+N++FEV+++  +  +++ +L+TYK  RG+  +    +K A+ S+LP  ++           D+ ++  ++  Q ++N      + ++R V+
Sbjct:  182 VVEGRGLARGEIGMASIDLKSPQIMLSQFADNTTYAKVITKLQVLSPLEIIMSNTACVVGNSTKLFTLITENFKNVNFTTVQRKYFNETKGLEYIEQLCIAEF-SSVLMEVQSRYYCLAAAAALLKYVEFIQNSVYAPKSLKIYFQGSEQTAMIDSSSAQNLELLVNNQDYRSNHTLFGVLNYTKTAGGSRRLRSNILEPLVDVETISMRLDCVQELLQDEELFFGLQSVISRFLDTEQLLSVLVQIPKQDTVNAAESKITNLIYLKHTLELVEPLKVTLKNCSTPLLRAYYGSLEDHRFGLILDKIKTVINDDARYMKGCLNMRTQKCYAVRSNISEFLDIARRTYTEIVDDIAGMIAQLAEKYSLPLRTSFSSSRGFFIQM-TTDCAALSSDQLPSEFIKISKVKNSYSFTSADLIKMNERCQESLREIYHMTYMIVCKLLSEIYEHIHCLYKLSDTVSMLDMLLSFAHACTLSDYVRPEFTDTLAIKQGWHPILEKISAEKPVANNTYITEGSNVLIITGPNMSGKSTYLKQIALCQIMAQIGSYVPAEYASFRIAAQIFTRISTDDDIETNSSTFMKEMKEIAYILHNANDKSLILIDELGRGTNTEEGIGISYAVCEHLLSIKAFTLFTTHFLELCHLDALYLNVENMHFEVQHVKNTSRNKDAILYTYKLSRGLTEEKNYGLKAAEASSLPSSIVL----------DARDITTQITRQILQNQRSSPEMDRQRAVY 911

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BLAST of mutS protein homolog 4 vs. UniProt/SwissProt
Match: sp|F4JP48|MSH4_ARATH (DNA mismatch repair protein MSH4 OS=Arabidopsis thaliana OX=3702 GN=MSH4 PE=2 SV=1)

HSP 1 Score: 394.815 bits (1013), Expect = 3.696e-122
Identity = 265/759 (34.91%), Postives = 414/759 (54.55%), Query Frame = 1

Query:  526 LIEGRGVASGEIGIASVDLKNPELELSQFSD-SIGYSRTLSKLYLKDP-VEIVFPHTMCENGVRSKLFQIVSEFMHKSSITT----IHRRYYNDKNGKEIIQHLCHKDYTS-SILYESREKYYALAACAAIIKYVEFIQNILFAPGSLQIIFSGSVKCAIIDIASVRNLELVE---NSKDLTENG--SLFSALNFTTTNGGYRLLRANILQPSFDIPTITSRYDCVEELMNNAELFFTLKSQIKHFVSLNH--LLSLCVQLPKNQT--------VKSAENTITQVIALKHVMELIPTLRATLQSFKSSLFIE-YHSLLVDSRYDEILSIINVVVHEDVHFEKGILQMRSQKLFAIKDGINVILDIARRSYSEQIEALRDEVQALSVEHALP-LRVAFSNSRGFYIQLPLTNSSVKPRLSLPFIKVAIVKNFITCTTEKIMKFNERLKGALAEIYLTAELLLSELIKAIRVHMGVLYRLSEISATLDLLL-SFAQV---SKMQNYIRPEFTDT--LAIKNCRNPLLDRLSNKEAISNHVYAANLSNFTIVTGANMSGKSMYLRQIALVQIMGQIGCFIPAEYASFRLSDHLFTRIGVDDDIQSNSSTFTIEMREMSYIINTITDNSLVLIDELGRGTSFDEGLGICFAICEHLLQTKAFIFIATHFRELSKLEILYPNVQNVNFEVKNLSESDGDENHLLFTYKCVRGVCPDFTNAMKLAKLSNLPKQLLFEAEKIYGRLGDSNELIIEVKSQFIRNIHK 2712
            LIE R   + E+G+A+ DL++  L LSQ+ + S  Y  T + L   DP V IV P+ +  +G+       VSE + +   T       R  ++D  G  +IQ+L  ++  +  +    ++ Y +LAA AA IK++E  + ++    SL + F+GS     ID  SV NLEL++   N+   T N   SLF     T T GG RLLRAN+LQP  DI TI +R DC++ELM+N +LFF L   ++ F       L   C + PK  T         + ++N I+ +I LK  ++ +P L   L+  K  L    Y S+  + RY  I   I  V+ +DV   +     R+Q+ FA+K GI+  LDIARR++ +  EA+ +       E  LP L++ F+N +GF+ ++P     V+ +L   F +V      I C++ ++   N R K A  E ++  E  L  L+ AIR  +  L  L+E+   LD+++ SFA       +  Y RPE TD+  LAI   R+P+L+ + N + +SN ++ +  +N  +V G NMSGKS YL+Q+ LV I+ QIGC++PA +A+ R+ D +FTR+G  D+++SNSSTF  EMRE ++I+  +T+ SL+++DELGR TS  +GL + ++ CE+LL  KA+   ATH   L++L  +YPNV+ ++F V      D  +N L F ++   G        + LA+++ LP  ++  A  I  R+ D     IE+       IH+
Sbjct:   15 LIENR---AKEVGMAAFDLRSASLHLSQYIETSSSYQNTKTLLRFYDPSVIIVPPNKLAADGMVG-----VSELVDRCYSTVRKVVFARGCFDDTKGAVLIQNLAAEEPLALGLDTYYKQHYLSLAAAAATIKWIEAEKGVIVTNHSLTVTFNGSFDHMNIDATSVENLELIDPFHNALLGTSNKKRSLFQMFKTTKTAGGTRLLRANLLQPLKDIETINTRLDCLDELMSNEQLFFGLSQVLRKFPKETDRVLCHFCFK-PKKVTEAVIGFENTRKSQNMISSIILLKTALDALPILAKVLKDAKCFLLANVYKSVCENDRYASIRKKIGEVIDDDVLHARVPFVARTQQCFALKAGIDGFLDIARRTFCDTSEAIHNLASKYREEFNLPNLKLPFNNRQGFFFRIP--QKEVQGKLPNKFTQVVKHGKNIHCSSLELASLNVRNKSAAGECFIRTETCLEALMDAIREDISALTLLAEVLCLLDMIVNSFAHTISTKPVDRYSRPELTDSGPLAIDAGRHPILESIHN-DFVSNSIFMSEATNMLVVMGPNMSGKSTYLQQVCLVVILAQIGCYVPARFATIRVVDRIFTRMGTMDNLESNSSTFMTEMRETAFIMQNVTNRSLIVMDELGRATSSSDGLAMAWSCCEYLLSLKAYTVFATHMDSLAELATIYPNVKVLHFYV------DIRDNRLDFKFQLRDGTLHVPHYGLLLAEVAGLPSTVIDTARIITKRITDKENKRIELNCGKHHEIHR 755

[Close]

BLAST of mutS protein homolog 4 vs. UniProt/SwissProt
Match: sp|Q23405|HIM14_CAEEL (MutS protein homolog him-14 OS=Caenorhabditis elegans OX=6239 GN=him-14 PE=1 SV=2)

HSP 1 Score: 348.591 bits (893), Expect = 2.180e-104
Identity = 221/724 (30.52%), Postives = 398/724 (54.97%), Query Frame = 1

Query:  523 LLIEGRGVASGEIGIASVDLKNPELELSQFSDSIGYSRTLSKLYLKDPVEIVFPHTMCENGVRSKLFQIVSEFMHKSSITTIHRRYYNDKNGKEIIQHLCHKDYTSSILYESREKYYALAACAAIIKYVEFIQNILFAPGSLQIIFSGSVKCAIIDIASVRNLELVENSK-------DLTENGSLFSALNFTTTNGGYRLLRANILQPSFDIPTITSRYDCVEELMNNAELFFTLKSQIKHFVSLNHLLSLCVQLPKNQTVKSAENTITQVIALKHVMELIPTLRATLQS--FKSSLFIEYHSLLVDSRYDEILSIINVVVHEDV-HFEKGILQMRSQKLFAIKDGINVILDIARRSYSEQIEALRDEVQALSVEHAL----PLRVAFSNSRGFYIQLPLTNSSVKPRLSLPFIKVAIVKNFITCTTEKIMKFNERLKGALAEIYLTAELLLSELIKAIRVHMGVLYRLSEISATLDLLLSFAQVSKMQNYIRPEFTDTLAIKNCRNPLLDRLSNKEAISNHVYAANLSNFTIVTGANMSGKSMYLRQIALVQIMGQIGCFIPAEYASFRLSDHLFTRIGVDDDIQSNSSTFTIEMREMSYIINTITDNSLVLIDELGRGTSFDEGLGICFAICEHLLQTKAFIFIATHFRELSKLEILYPNVQNVNFEVKNLSESDGDENHLLFTYKCVRGVCPDFTNAMKLAKLSNLPKQLLFEAEKIYGRL 2652
            +++EGRG   G IGIA  D   PE+ L +F DS  Y+   + + + +  +IV  +   E G    L + +     ++S+ +I  +Y+N + G+  +Q L + +  S++      +  AL A A ++KY+   + + F   SL+I   G     +ID  S  +LE+V+           + +  +L S LN T T  GYRLLR+++LQPS D+  I SR + +EEL+   +L   L+  +     L+ ++++C+Q   + TV+ +E  I Q+I L H +++I  +R  L S   KS++ IE    L D R+D+I++I+   V + +   +K  L +++ K +AI+  + V LD+AR++Y E I  + +E  A  +         +R++FS SRGF+    +T  +    +   F+ V   +  +T  + K++ +N+RL+  +AE++L +++++ ++I+ ++  + VLY   +  +++D L   A  S +++  +P F  + +I   R+P+LD   +++ I+N         F I+TG NM+GKS YL+Q A + IM QIGCFIPA YAS  + + +F+R+G +D++  N S F  EM + + I+     NSLV++DEL R TS +EG+ I +AICE +L+ +++ F+ATHF +++ L      + N +F    L ++D +       +K +RG         +L +LS +P +++  A+ +   L
Sbjct:   56 VVMEGRGSCEGHIGIALHDTCFPEIHLCEFVDSREYTTLKTMINVHEAFDIVIQNGNEERGSTKLLGEALMTAFPEASLQSISSKYFNSERGERQLQSLMNAE-VSTVSEGCLRRTLALGALAVLLKYIHETRCVFFRVKSLRIKEMGVNDTCMIDFVSWESLEIVDADDASKARKFQMKQKRTLMSVLNHTVTTNGYRLLRSSVLQPSTDVYLIQSRQEAIEELIGKPQLKDKLRRTLSRAHELDRVIAMCIQTSTSWTVRESEAKINQIIKLMHTLKVIQGIRTLLHSAKMKSNILIEKTEFLKDPRFDQIMNILVEKVDDSLLDGKKNSLHLQNTKCYAIRHFVAVQLDLARQTYEEIIRNV-EETGAREIAEYFHGNSSVRLSFSQSRGFHYTF-VTRQAESVTIPRYFLDVFRNRTTVTFNSRKVIAYNDRLEQVVAEMFLASDVIVCDMIEEMQPMIPVLYYAMDALSSIDFLCGLATYSDLRDTCKPTFGPSFSISQGRHPILDWDDSEKTITNDTCLTRDRRFGIITGPNMAGKSTYLKQTAQLAIMAQIGCFIPANYASLPIFNRIFSRMGHNDELIRNKSAFASEMSDAAAIVQYADKNSLVVLDELARSTSTEEGIAITYAICEKVLKLQSYTFLATHFLDIAALANYSNAIDNYHF----LPQTDENSTK---KHKLLRGQYRGPLYGFELVELSTIPDEVIEHAQSLATEL 769

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BLAST of mutS protein homolog 4 vs. UniProt/SwissProt
Match: sp|P40965|MSH4_YEAST (MutS protein homolog 4 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=MSH4 PE=1 SV=2)

HSP 1 Score: 328.946 bits (842), Expect = 9.765e-97
Identity = 229/684 (33.48%), Postives = 367/684 (53.65%), Query Frame = 1

Query:  520 CLLIEGRGVASGEIGIASVDLKNPELELSQFSDSIGYSRTLSKLYLKDPVEIVFPHTMCENGVRSKLFQIVSEFMHKSSITTIHRRYYNDKNGKEIIQHLCHKDYTSSI-LYESREKYYALAACAAIIKYVEFI----QNILFAPGSLQIIFSGSVKCAIIDIASVRNLELVENSKDLTENG-SLFSALNFTTTNGGYRLLRANILQPSFDIPTITSRYDCVEELMNNAELFFTLKSQIKHFVSLNHLLS--LCVQLPKNQTVKSAENTITQVIALKHVMELIPTLRATL--QSFKSSLFIEYHSLLVDSRYDEILSIINVVVHEDVHFEKGILQMRSQKLFAIKDGINVILDIARRSYSEQIEALRDEVQALSVEHALPLRVAFSNSRGFYIQLPLTNSSVKPRLSLP--FIKVAIVKNFITCTTEKIMKFNERLKGALAEIYLTAELLLSELIKAIRVHMGVLYRLSEISATLDLLLSFAQVSKMQNYIRPEFTDTLAIKNCRNPLLDRLSNKEAISNHVYAA-NLSNFTIVTGANMSGKSMYLRQIALVQIMGQIGCFIPAEYASFRLSDHLFTRIGVDDDIQSNSSTFTIEMREMSYIINTITDNSLVLIDELGRGTSFDEGLGICFAICEHLLQTKAFIFIATHFRELSKLEILYPNVQNVNFEVKNLSESDGDENHLL 2532
            C + E     S  IG+  ++    ++ LS F DS  Y R + KL +  P EI+ P +     V      I         I    R+ +N ++G   I      D    + + E  +K +AL A +A I Y+E I       L A   L+I F G+    +ID  +VR LELVEN  D  +NG SL+  L+ T+T  G R LR +ILQP  D  +I  R + +EEL  N +L   L+ ++K    L+ L S  LC+    N +    +  I  V+ LK  ++ + +L+  L  Q  +S L  E   +  +    EI  +IN  ++ED  +    +Q+ +Q+ +A+K   N +LD++R+ Y E  E    EV+ L+ ++ + L   + ++RGFY+++           +LP  FI   I KN+I CTT  I+K N RLK  + EI L +E  + EL+  I  H+  L+ ++E  A LDL+ SF    K  NY  P FT+ L I++ R+PLL+++  K  + N + +  + S+  I+TG NMSGKS+YL+Q+AL+ IM Q+G  IPA Y SF +   L  R+  +D ++  SS F  EM+EM+Y ++ I   +L+++DELGRG+S  +G  +  A+ EHLL+T+A +F++THF+++ K+    P V +++ +   L+++    N+ L
Sbjct:  107 CCIYEVPRDISTRIGLCIINCNTGQMYLSDFMDSQIYIRVVHKLQIYQPTEILIPSSSLAPTVSKLATMIKFNVAETVKIEEGSRKCFNSQDGLAAITKYLMDDTKKDLKIEEIIDKTFALCAASAAISYMEEIISKSSRNLNAFRKLRIQFEGTENTMLIDSKTVRGLELVENKLD--KNGISLWKFLDTTSTKMGQRSLRNSILQPLTDRGSIEMRLEALEELKANDDLLQKLRLEMKSLPDLDKLFSRLLCI----NHSAIKPDQRINYVLLLKETLQSVKSLKDALNDQLIQSRLISETKKIFNNDAIMEIEKLINSCINEDCVWASSAIQLLNQRSYAVKSDSNGLLDVSRQIYKEVKEEFFREVEDLTAKNKINLDHNYDSARGFYLRIK-RQEFTDDVATLPDVFISRTIKKNYIECTTLNIIKKNARLKEVMEEILLLSEETVDELLDKIATHISELFMIAEAVAILDLVCSFTYNLKENNYTIPIFTNNLLIRDSRHPLLEKVL-KNFVPNTISSTKHSSSLQIITGCNMSGKSVYLKQVALICIMAQMGSGIPALYGSFPVFKRLHARV-CNDSMELTSSNFGFEMKEMAYFLDDINTETLLILDELGRGSSIADGFCVSLAVTEHLLRTEATVFLSTHFQDIPKIMSKKPAVSHLHMDAVLLNDNSVKMNYQL 781

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BLAST of mutS protein homolog 4 vs. TrEMBL
Match: W4ZC78 (DNA_MISMATCH_REPAIR_2 domain-containing protein OS=Strongylocentrotus purpuratus OX=7668 PE=4 SV=1)

HSP 1 Score: 720.309 bits (1858), Expect = 0.000e+0
Identity = 355/712 (49.86%), Postives = 500/712 (70.22%), Query Frame = 1

Query:  526 LIEGRGVASGEIGIASVDLKNPELELSQFSDSIGYSRTLSKLYLKDPVEIVFPHTMCENGVRSKLFQIVSEFMHKSSITTIHRRYYNDKNGKEIIQHLCHKDYTSSILYESREKYYALAACAAIIKYVEFIQNILFAPGSLQIIFSGSVKCAIIDIASVRNLELVENSKDLTENGSLFSALNFTTTNGGYRLLRANILQPSFDIPTITSRYDCVEELMNNAELFFTLKSQIKHFVSLNHLLSLCVQLPKNQTVKSAENTITQVIALKHVMELIPTLRATLQSFKSSLFIEYHSLLVDSRYDEILSIINVVVHEDVHFEKGILQMRSQKLFAIKDGINVILDIARRSYSEQIEALRDEVQALSVEHALPLRVAFSNSRGFYIQLPLTNSSVKPRLSLP--FIKVAIVKNFITCTTEKIMKFNERLKGALAEIYLTAELLLSELIKAIRVHMGVLYRLSEISATLDLLLSFAQVSKMQNYIRPEFTDTLAIKNCRNPLLDRLSNKEAISNHVYAANLSNFTIVTGANMSGKSMYLRQIALVQIMGQIGCFIPAEYASFRLSDHLFTRIGVDDDIQSNSSTFTIEMREMSYIINTITDNSLVLIDELGRGTSFDEGLGICFAICEHLLQTKAFIFIATHFRELSKLEILYPNVQNVNFEVKNLSESDGDENHLLFTYKCVRGVCPDFTNAMKLAKLSNLPKQLLFEAEKIYGRLG 2655
            ++EGRG+A GEIG+AS+DLK PEL LSQFSDS  Y +  +KL +  P+EI+  HT CE G  +KLF+++S+      +TTI R+Y+N+  G  +++ LC  D+ SS+  E   KYY LAA AA++KYVEFIQN ++AP SL+++F GS + A+ID  + RNLELV+N KD   + +LF  LN+T T GG RL+R+NILQP FD  TI  R D V EL  N ELF+ L+S +  F+ ++HLLSLCVQ+PK ++VKS+E  IT VI LKH +EL+  L   LQS +S L   YH  L D+R+ +IL  I  V++++  ++KG L MR+QK FA+K  IN +LD+ARR+Y+E ++ + + ++ LS EH L LR ++S +RGF+IQL        P  SLP  FIKV   KN ++ TT  ++K N+R++ +L EIYL   +++S+L+  IR H+G LY+L+E  + +D+L+SFA    + +Y+RP+FTDTLAIK  R+P+LD++S    + N++YA+   NF I+TG NMSGKS YL+QIAL+QIM QIGCF+PAEYASFR+ D +F+RIG DDDI++N+S+FT+EMRE++YI+   T  SLV+IDELGRGTS DEG+GIC AICE+LL  KAF F ATHF EL+ L+ LYPNV+N +F+V+       D N L +T+   RG   +    +KLA++S LP  ++ EA+ +  +L 
Sbjct:    4 IVEGRGIAQGEIGMASIDLKQPELILSQFSDSQTYVKVTTKLQVLQPIEIIMSHTACEGGAMTKLFKLISDNFQGLDVTTIQRKYFNETKGLSVVKQLCVADF-SSVEMEITSKYYCLAAAAALLKYVEFIQNSVYAPNSLKVVFRGSEQSAVIDAVTARNLELVQNRKDPKSDHTLFGVLNYTKTMGGARLMRSNILQPPFDEETIKLRLDVVAELTENEELFYNLQSVLSRFLDVDHLLSLCVQIPKEESVKSSEQKITNVIHLKHTLELVEPLHVALQSAQSKLPQAYHKTLQDTRFQQILEKIATVINDETRYQKGTLNMRTQKCFAVKPEINGLLDVARRTYTELVDDISEMIKQLSDEHGLMLRTSYSTARGFFIQLYCKGKYSIPVESLPPVFIKVVKAKNTLSFTTTDLIKMNDRVRESLNEIYLMTNVVVSQLLNDIREHVGCLYKLAECVSVIDMLVSFAHACTLSDYVRPDFTDTLAIKQARHPILDKISFDPPVPNNIYASEEGNFLIITGPNMSGKSTYLKQIALLQIMAQIGCFVPAEYASFRICDQVFSRIGCDDDIETNASSFTLEMREINYIVQNCTHESLVIIDELGRGTSSDEGVGICHAICEYLLSLKAFTFFATHFMELTNLDALYPNVENYHFQVEQSLAEGEDSNRLSYTHILSRGRTTEQYYGIKLAEISALPPSIVREAKALSQKLA 714

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BLAST of mutS protein homolog 4 vs. TrEMBL
Match: A0A0L8GSV3 (DNA_MISMATCH_REPAIR_2 domain-containing protein OS=Octopus bimaculoides OX=37653 GN=OCBIM_22028772mg PE=4 SV=1)

HSP 1 Score: 716.457 bits (1848), Expect = 0.000e+0
Identity = 353/742 (47.57%), Postives = 517/742 (69.68%), Query Frame = 1

Query:  526 LIEGRGVASGEIGIASVDLKNPELELSQFSDSIGYSRTLSKLYLKDPVEIVFPHTMCENGVRSKLFQIVSEFMHKSSITTIHRRYYNDKNGKEIIQHLCHKDYTSSILYESREKYYALAACAAIIKYVEFIQNILFAPGSLQIIFSGSVKCAIIDIASVRNLELVENSKDLTENGSLFSALNFTTTNGGYRLLRANILQPSFDIPTITSRYDCVEELMNNAELFFTLKSQIKHFVSLNHLLSLCVQLPKNQTVKSAENTITQVIALKHVMELIPTLRATLQSFKSSLFIEYHSLLVDSRYDEILSIINVVVHEDVHFEKGILQMRSQKLFAIKDGINVILDIARRSYSEQIEALRDEVQALSVEHALPLRVAFSNSRGFYIQLPLTNSSVKPRLSLP--FIKVAIVKNFITCTTEKIMKFNERLKGALAEIYLTAELLLSELIKAIRVHMGVLYRLSEISATLDLLLSFAQVSKMQNYIRPEFTDTLAIKNCRNPLLDRLSNKEAISNHVYAANLSNFTIVTGANMSGKSMYLRQIALVQIMGQIGCFIPAEYASFRLSDHLFTRIGVDDDIQSNSSTFTIEMREMSYIINTITDNSLVLIDELGRGTSFDEGLGICFAICEHLLQTKAFIFIATHFRELSKLEILYPNVQNVNFEVKNLSESDGDENHLLFTYKCVRGVCPDFTNAMKLAKLSNLPKQLLFEAEKIYGRLGDSNELIIEVKSQFIRNIHKGRPLGKERGVF 2745
            L+EGRG+A GEIG+AS+DLK P L LSQFSDS  Y + ++KL +  P+EIV P T CENG  SKLFQ++S  +    ++T+ R+Y+N+  G + I+ LC  DY +S+  E   KYY LA  +A++KYVEFIQNI++AP +L+IIF G     +ID+ + +NLELV+N +D   + SLF  LN+  T GG RLLRANILQP  DI TIT R D V EL +N +LFF L+S +K F+ ++HLLSLCVQ+PK +T+++AE+ IT +I LKH++E++P L+  L+   ++L + Y   LVD R + + S I+ ++HED  ++KG+L M++QK FA+K G+   LD+ARR+Y+E I+ + + V+ LS ++ LPL+ +++++RGF++QL   N       SLP  FIKV   KN ++ TT  ++K N+R+K +L EIYL   ++++EL+  IR  +  LY+LSE  +TLD+L  FA +  + +Y RPEFTDT+AIK  R+P+L++++ +  + N+ YA+N SNF I+TG NMSGKS YLRQ+AL+QIM QIGCF+PA YASFR+SD +FTRIG DDD+++N+STF +EMRE++YII   +D SL++IDELGRGTS  EGLGIC+AICE+LL TKA     THF EL+ L+ +YPNV+N  FEVK +   +G+   L +T+   +G   +    ++LA++S +P+ ++ EA+++          I+ V  +  +N+ K     K+R VF
Sbjct:  100 LVEGRGLAKGEIGMASIDLKCPVLVLSQFSDSQTYVKVMTKLQILQPIEIVIPSTACENGNMSKLFQVISNNLSNCCMSTVQRKYFNESKGLQFIRQLCLPDY-NSVEMEVASKYYCLATASALLKYVEFIQNIVYAPSTLKIIFRGCENTTMIDVTTAKNLELVQNLRDPKSSHSLFGILNYCKTAGGVRLLRANILQPPSDIETITLRQDVVSELTDNEDLFFNLQSILKRFLDVDHLLSLCVQMPKQETIRTAESKITNIIYLKHILEMLPALQDALKKSDNTLLVAYSKALVDPRIEIMKSKIDSIIHEDTKYQKGVLNMKTQKCFAVKSGL---LDVARRTYTEIIDDIAELVRQLSEKYKLPLKTSYNSTRGFFMQLYSGNKDKYMVDSLPSIFIKVGKHKNTLSFTTTDLIKLNDRVKESLQEIYLMTNIVVTELLNDIRSCISCLYKLSECVSTLDMLAGFAHLCTLSDYTRPEFTDTVAIKQSRHPILEKIAREPPVPNNTYASNDSNFIIITGPNMSGKSTYLRQVALLQIMAQIGCFVPATYASFRISDQIFTRIGSDDDLETNASTFMLEMREINYIIQNASDTSLIIIDELGRGTSVKEGLGICYAICEYLLSTKAITLFVTHFMELTNLDEVYPNVENYYFEVKRIFCQEGNCEKLTYTHILSQGKTNEKHYGIQLAEVSTIPRSVVEEAKQLLQ--------IVSVNKKVDQNLKK--EARKQRAVF 827

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BLAST of mutS protein homolog 4 vs. TrEMBL
Match: A0A1S3J8M3 (mutS protein homolog 4 OS=Lingula unguis OX=7574 GN=LOC106170772 PE=4 SV=1)

HSP 1 Score: 702.975 bits (1813), Expect = 0.000e+0
Identity = 346/717 (48.26%), Postives = 498/717 (69.46%), Query Frame = 1

Query:  526 LIEGRGVASGEIGIASVDLKNPELELSQFSDSIGYSRTLSKLYLKDPVEIVFPHTMCENGVRSKLFQIVSEFMHKSSITTIHRRYYNDKNGKEIIQHLCHKDYTSSILYESREKYYALAACAAIIKYVEFIQNILFAPGSLQIIFSGSVKCAIIDIASVRNLELVENSKDLTENGSLFSALNFTTTNGGYRLLRANILQPSFDIPTITSRYDCVEELMNNAELFFTLKSQIKHFVSLNHLLSLCVQLPKNQTVKSAENTITQVIALKHVMELIPTLRATLQSFKSSLFIEYHSLLVDSRYDEILSIINVVVHEDVHFEKGILQMRSQKLFAIKDGINVILDIARRSYSEQIEALRDEVQALSVEHALPLRVAFSNSRGFYIQLPLTNSSVKPRLS-LP--FIKVAIVKNFITCTTEKIMKFNERLKGALAEIYLTAELLLSELIKAIRVHMGVLYRLSEISATLDLLLSFAQVSKMQNYIRPEFTDTLAIKNCRNPLLDRLSNKEAISNHVYAANLSNFTIVTGANMSGKSMYLRQIALVQIMGQIGCFIPAEYASFRLSDHLFTRIGVDDDIQSNSSTFTIEMREMSYIINTITDNSLVLIDELGRGTSFDEGLGICFAICEHLLQTKAFIFIATHFRELSKLEILYPNVQNVNFEVKNLSESDGDENHLLFTYKCVRGVCPDFTNAMKLAKLSNLPKQLLFEAEKIYGRLGDSNE 2667
            L+EGRG+A GEIG+A +DLK+P L +SQFSDS  Y + ++KL +  P EI+ P+T+CE+G  + LF+ +S     ++I T+ R+Y+N+  G + I+ L   + T+ +  E   KYY LA  AA++KYVEFIQN+++AP SL++IF GS    +ID  +  +LEL++N +D     +LF  LNFT T GG RLLR+NILQP  D+ TIT+R D V+EL  N ELF+ L+S +  F+ ++HLLSLCVQLPK +T+K+AEN IT VI LKH +EL+  L+  L+   +SLF  YH  L DSR+D I   ++ V+HED  F+KG L MR+QK FA+K  IN +LD+ARR+Y+E ++ + + ++ LS EH LPL+  +S +RGFYI +        P  + LP  FIKV   KN I+ TT  ++K N+R++ +L EI L + +++SEL+  IR  +G LY+L+E  A+LDLL+S A    +  Y+RPEFTDTLA+K  R+P+LD++S +  + N+VYA++ SNF I+TG NMSGKS YLRQIAL+QIM QIG ++PA++ASFR+ D +F+RIG DDDI++NSSTF +EMRE++YII   +  SL++IDELGRGTS DEG+GI  A+CEHLL  KAF F ATHF EL+ L  LYPNV+N +FEV+ L  ++     L +T+   +G+  +    ++LA++S LP  ++ +A+ +   + +  E
Sbjct:  130 LVEGRGLARGEIGMACIDLKSPVLVVSQFSDSQTYIKVMTKLQILQPAEIIMPNTVCESGNMTTLFKQISNTFQNANIATVQRKYFNETKGLQYIKQLSLPECTT-VEMELAGKYYCLATTAALLKYVEFIQNVVYAPSSLKVIFKGSEMTTMIDSTTAGSLELLQNLQDPKSEHTLFGMLNFTKTTGGARLLRSNILQPPCDLETITTRLDAVQELTENEELFYNLQSVLSRFMDIDHLLSLCVQLPKQETLKTAENKITNVIYLKHTLELVEPLKEALKDSTNSLFKAYHDTLGDSRFDVIREKVHSVIHEDTRFQKGSLNMRTQKCFAVKPNINGLLDVARRTYTEIVDDISELIKQLSTEHMLPLKTGYSVTRGFYIHMTCGGKDGGPSAAELPGIFIKVNKFKNTISFTTTDLIKMNDRIRESLQEICLISNVVVSELLTDIRSQIGCLYKLTECVASLDLLVSLAHACSLSEYVRPEFTDTLAVKQGRHPILDKISVETPVPNNVYASDESNFLIITGPNMSGKSTYLRQIALLQIMAQIGSWVPADFASFRVCDQIFSRIGSDDDIETNSSTFMLEMREINYIIQNASATSLIIIDELGRGTSADEGIGISQAVCEHLLSLKAFTFFATHFCELTNLGNLYPNVENYHFEVQRLYAAETHHEKLQYTHVLSKGISKEKHYGIELAQVSTLPSSIVEDAKLVAKAIAEQKE 845

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BLAST of mutS protein homolog 4 vs. TrEMBL
Match: A0A210Q4E9 (MutS protein-like 4 OS=Mizuhopecten yessoensis OX=6573 GN=KP79_PYT08491 PE=4 SV=1)

HSP 1 Score: 695.656 bits (1794), Expect = 0.000e+0
Identity = 333/707 (47.10%), Postives = 508/707 (71.85%), Query Frame = 1

Query:  526 LIEGRGVASGEIGIASVDLKNPELELSQFSDSIGYSRTLSKLYLKDPVEIVFPHTMCENGVRSKLFQIVSEFMHKSSITTIHRRYYNDKNGKEIIQHLCHKDYTSSILYESREKYYALAACAAIIKYVEFIQNILFAPGSLQIIFSGSVKCAIIDIASVRNLELVENSKDLTENGSLFSALNFTTTNGGYRLLRANILQPSFDIPTITSRYDCVEELMNNAELFFTLKSQIKHFVSLNHLLSLCVQLPKNQTVKSAENTITQVIALKHVMELIPTLRATLQSFKSSLFIEYHSLLVDSRYDEILSIINVVVHEDVHFEKGILQMRSQKLFAIKDGINVILDIARRSYSEQIEALRDEVQALSVEHALPLRVAFSNSRGFYIQLPLTNSSVKPRLS---LP--FIKVAIVKNFITCTTEKIMKFNERLKGALAEIYLTAELLLSELIKAIRVHMGVLYRLSEISATLDLLLSFAQVSKMQNYIRPEFTDTLAIKNCRNPLLDRLSNKEAISNHVYAANLSNFTIVTGANMSGKSMYLRQIALVQIMGQIGCFIPAEYASFRLSDHLFTRIGVDDDIQSNSSTFTIEMREMSYIINTITDNSLVLIDELGRGTSFDEGLGICFAICEHLLQTKAFIFIATHFRELSKLEILYPNVQNVNFEVKNLSESDGDENHLLFTYKCVRGVCPDFTNAMKLAKLSNLPKQLLFEA 2631
            ++EGRG+A GEIG+AS+DLK P L LSQFSD+  Y +T++KL +  P+EI+ P+T CENG  +KL +++++    +SI+T+ R+Y+N+  G + ++ LC  ++ +++  E R KYYALAA A+++KYVEF+QN+++APGSL+++F GS    +ID +S +NLEL++N +D T + +L+  LN+T T GG RLLRANILQP  D+ TIT R D + EL    E+F+ L++ I  F  ++HLLSL +Q+PK +T+K AE+ IT +I LKH +ELI  L+  L+  ++ L   Y   L D R+D I++ I+ V+HED  F+KG L MR+QK FA+K  IN +LD+ARR Y+E ++ + + V  L  ++ LPL+ +++++RGF+IQ   T++S K  L+   LP  FIKV   K+ ++ TT  ++K N R++ +L EIYL A ++++ L+  IR ++G LY+L+E  A +D+LLSFA V  + NY+RPEFTDTLAIK  R+P+L++++  + + N+ YA++ SNF ++TG NMSGKS YLRQI L+QIM QIGC +PAEYASFR++D +F+RI  DD++++NSSTFT+EM+E++YII   ++ SLV++DELGRGTS +EG+GIC +ICE+L+Q KAF    THF EL+ L++LYPNV+N  F+V+    +   E  ++FT+   +G   +    M+LAK+S+LP+ ++ +A
Sbjct:  120 IVEGRGLAKGEIGLASLDLKCPHLTLSQFSDTQTYVKTITKLQILQPIEIIVPNTACENGTMTKLLKLINDQFQNTSISTVQRKYFNETRGLQYVKQLCVPEF-NTVEMEVRLKYYALAAVASLMKYVEFMQNMMYAPGSLKVVFQGSENTTMIDASSAKNLELLQNLRDPTSDITLYGILNYTKTPGGARLLRANILQPPSDLETITMRQDAIGELTEKEEVFYNLQTVIGQFPDVDHLLSLLLQIPKQETIKIAESKITNIIYLKHTLELIEPLKEALKDCENPLLKAYCKSLDDPRFDIIITKISSVIHEDTRFQKGTLHMRTQKCFAVKPNINGLLDVARRMYTEIVDDISELVTQLGGQYGLPLKTSYNSARGFFIQ---TSASGKDGLTADNLPGIFIKVTKAKSTLSFTTTDLIKLNARIQQSLEEIYLMANIVVTALLNDIRGYLGCLYKLTESVAIIDVLLSFAHVCTLSNYVRPEFTDTLAIKQGRHPILEKIAIGQTVPNNTYASDESNFLVITGPNMSGKSTYLRQIPLLQIMAQIGCSVPAEYASFRIADQIFSRISTDDEMETNSSTFTLEMKEVNYIIQNASNRSLVIMDELGRGTSPEEGVGICHSICEYLIQLKAFTVFVTHFLELTNLDVLYPNVENYCFDVQRSVCTQSAEEKIIFTHTLQKGKTEERHYGMELAKMSSLPRDIIEKA 822

[Close]

BLAST of mutS protein homolog 4 vs. TrEMBL
Match: A0A5N3WK57 (Uncharacterized protein OS=Muntiacus muntjak OX=9888 GN=FD754_006020 PE=4 SV=1)

HSP 1 Score: 681.789 bits (1758), Expect = 0.000e+0
Identity = 334/742 (45.01%), Postives = 512/742 (69.00%), Query Frame = 1

Query:  526 LIEGRGVASGEIGIASVDLKNPELELSQFSDSIGYSRTLSKLYLKDPVEIVFPHTMCENGVRSKLFQIVSEFMHKSSITTIHRRYYNDKNGKEIIQHLCHKDYTSSILYESREKYYALAACAAIIKYVEFIQNILFAPGSLQIIFSGSVKCAIIDIASVRNLELVENSKDLTENGSLFSALNFTTTNGGYRLLRANILQPSFDIPTITSRYDCVEELMNNAELFFTLKSQIKHFVSLNHLLSLCVQLPKNQTVKSAENTITQVIALKHVMELIPTLRATLQSFKSSLFIEYHSLLVDSRYDEILSIINVVVHEDVHFEKGILQMRSQKLFAIKDGINVILDIARRSYSEQIEALRDEVQALSVEHALPLRVAFSNSRGFYIQLPLTNSSVKPRLSLP--FIKVAIVKNFITCTTEKIMKFNERLKGALAEIYLTAELLLSELIKAIRVHMGVLYRLSEISATLDLLLSFAQVSKMQNYIRPEFTDTLAIKNCRNPLLDRLSNKEAISNHVYAANLSNFTIVTGANMSGKSMYLRQIALVQIMGQIGCFIPAEYASFRLSDHLFTRIGVDDDIQSNSSTFTIEMREMSYIINTITDNSLVLIDELGRGTSFDEGLGICFAICEHLLQTKAFIFIATHFRELSKLEILYPNVQNVNFEVKNLSESDGDENHLLFTYKCVRGVCPDFTNAMKLAKLSNLPKQLLFEAEKIYGRLGDSNELIIEVKSQFIRNIHKGRPLGKERGVF 2745
            ++EGRG+A GEIG+AS+DLK+P++ LSQF+D+  Y++ ++KL +  P+EI+  +T C  G  +KLF +++E     + TTI R+Y+N+  G E I+ LC  ++ +++L E + KYY LAA AA++KYVEFIQN ++AP SL+I F GS + A+ID +S +NLEL+ N++D   N +LF  LN+T T GG R LR+NIL+P  D+ TI  R DCV+EL+ + ELFF L+S I  F+    LLS+ VQ+PK  TV +AE+ IT +I LKH +EL+  L+ TL++  + L   Y+  L D R+  IL  I  V+++D  + KG L MR+QK +A++  IN  LDIARR+Y+E ++ +   +  L+ +++LPLR +FS++RGF+IQ+  T+ +V P   LP  FIK++ VKN  + T+  ++K NER + +L EIY    +++ +L+  I  H+  LY+LS+  + LD+LLSFA    + +Y+RPEFTDTLAIK   +P+L+R+S ++ ++N+ Y    SNF I+TG NMSGKS YL+QIAL QIM QIG ++PAEY+SFR+++ +FTRI  DDDI++NSSTF  EM+E++YI++   D SL+LIDELGRGT+ +EG+GIC+A+CEHLL  KAF   ATHF EL ++++LYPNV+N++FEV+++  +  ++  +L+TYK  +G+  +    +K A++S+LP  ++ +A+ I  R          +  Q ++N      + ++R V+
Sbjct:  162 VVEGRGLARGEIGMASIDLKSPQIVLSQFADNTTYAKVITKLKILSPLEIIMSNTACVVGNSTKLFTLITENFKNVNFTTIQRKYFNETKGLEYIEQLCIAEF-NTVLMEVQSKYYCLAAVAALLKYVEFIQNSVYAPKSLKICFQGSEQTAMIDSSSAQNLELLINNQDSRNNHTLFGVLNYTKTPGGSRRLRSNILEPLVDVETINMRLDCVQELLQDEELFFGLQSVIARFLDTEQLLSVLVQIPKQDTVNAAESKITNLIYLKHTLELVDPLKITLKNCNTPLLRAYYGSLEDKRFGIILDKIKTVINDDARYMKGCLNMRTQKCYAVRSNINEFLDIARRTYTEIVDDIAGMITQLAEKYSLPLRTSFSSARGFFIQM-TTDCTVLPNDQLPSEFIKISKVKNSYSFTSTDLIKMNERCQESLREIYHMTYMIVCKLLSEIYEHIHCLYKLSDTVSMLDMLLSFAHACTLSDYVRPEFTDTLAIKQGWHPILERISVEKPVANNTYITEGSNFFIITGPNMSGKSTYLKQIALCQIMAQIGSYVPAEYSSFRIAEQIFTRISTDDDIETNSSTFMKEMKEIAYILHNANDKSLILIDELGRGTNTEEGIGICYAVCEHLLSLKAFTLFATHFLELCQIDVLYPNVENMHFEVQHVKNTSRNKEAILYTYKLSKGLTEEKNYGLKAAEVSSLPPSIVLDAKDITTR----------ITGQILQNQRSTPEMERQRAVY 891

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BLAST of mutS protein homolog 4 vs. Ensembl Cavefish
Match: msh4 (mutS homolog 4 [Source:ZFIN;Acc:ZDB-GENE-131121-643])

HSP 1 Score: 623.239 bits (1606), Expect = 0.000e+0
Identity = 319/712 (44.80%), Postives = 475/712 (66.71%), Query Frame = 1

Query:  526 LIEGRGVASGEIGIASVDLKNPELELSQFSDSIGYSRTLSKLYLKDPVEIVFPHTMCENGVRSKLFQIVSEFMHKSSITTIHRRYYNDKNGKEIIQHLCHKDYTSSILYESREKYYALAACAAIIKYVEFIQNILFAPGSLQIIFSGSVKCAIIDIASVRNLELVENSKDLTENGSLFSALNFTTTNGGYRLLRANILQPSFDIPTITSRYDCVEELMNNAELFFTLKSQIKHFVSLNHLLSLCVQLPKNQTVKSAENTITQVIA-LKHVMELIPTLRATLQSFKSSLFIEYHSLLVDSRYDEILSIINVVVHEDVHFEKGILQMRSQKLFAIKDGINVILDIARRSYSEQIEALRDEVQALSVEHALPLRVAFSNSRGFYIQLPLTNSSVKPRLSLP--FIKVAIVKNFITCTTEKIMKFNERLKGALAEIYLTAELLLSELIKAIRVHMGVLYRLSEISATLDLLLSFAQVSKMQNYIRPEFTDTLAIKNCRNPLLDRLSNKEAISNHVYAANLSNFTIVTGANMSGKSMYLRQIALVQIMGQIGCFIPAEYASFRLSDHLFTRIGVDDDIQSNSSTFTIEMREMSYIINTITDNSLVLIDELGRGTSFDEGLGICFAICEHLLQTKAFIFIATHFRELSKLEILYPNVQNVNFEVKNLSESDGDENHLLFTYKCVRGVCPDFTNAMKLAKLSNLPKQLLFEAEKIYGRL 2652
            ++EGRG+A GEIG++S+++K+PEL LSQF+D+  Y++ ++KL++  P+EI+ P T  E G  +KLF +++E +   S T I R+Y+N++ G E IQ LC  ++ S++L E + KYY LA+ AA++KYVEFIQN ++AP SL++ F+GS +  +ID  S +NLELV N++D +++ +LF  LN T T GG R LR+NIL+P  D+ TI +R D ++EL+ + ELFF LKS I HF+ ++ LLS  VQ+PK +T +     I  ++A +KH    +  L  ++  F  S            R+  IL  I  V+++D    KG L MR+QK +A++  +N  LDIARR+Y+E ++ +   V  L  ++ LPLR  FS +RGF+IQL L    V P   LP  FIK    KN  + TT  +MK N R + AL EI+  + +++  L+  +   +  LY+LS+  + LD+LLS A    + +Y+RPEFTDTLAIK  R+P L+R++ K+ ISN+ Y +  SNF IVTG NMSGKS YLRQ+AL QIM QIG F+PAEYASFR++D +FTRIGVDDD ++NSSTF +EM+E+SYI +T ++ SL++IDELGRGTS +EG+GIC A+CE L+  KAF   ATH+ EL +LE LYPNV+N + +V+++   D     +++TY   RG   +    ++ A+++++P  ++ EA+ I  ++
Sbjct:   21 VVEGRGLARGEIGLSSINMKSPELVLSQFADTGTYAKVITKLHILMPLEILMPDTASEKGQGTKLFNLITENVPSVSFTAIQRKYFNERKGLEYIQQLCAPEF-STVLMEVQTKYYCLASAAALLKYVEFIQNSVYAPKSLKVSFTGSEQTTMIDSVSAKNLELVINNRDQSDH-TLFGVLNHTKTPGGGRRLRSNILEPLLDVDTINTRLDAIQELLQDEELFFGLKSAITHFLDVDQLLSSLVQVPKQETSQQVCYFIDSLLAWIKHDFYFLQKLTFSIAFFHFS----------SHRFKSILDEIKTVINDDTTSLKGSLNMRTQKCYAVRPNVNEFLDIARRAYTEVVDDIAGLVDQLGEKYGLPLRTIFSTARGFFIQLSL-EGVVLPEGHLPEEFIK----KNNYSFTTLDLMKMNSRCEEALKEIFHMSYMVICRLLNGVYEQIHCLYKLSDAVSMLDMLLSLANACTLSDYVRPEFTDTLAIKQGRHPTLERITGKQPISNNSYISEGSNFVIVTGPNMSGKSTYLRQVALCQIMAQIGSFVPAEYASFRVADQIFTRIGVDDDFETNSSTFMVEMKEVSYITHTASERSLIIIDELGRGTSAEEGIGICHAVCEFLINLKAFTLFATHYLELCQLETLYPNVENQHMQVQHIRREDNSTESVVYTYLLTRGFSEERNYGIRAAEMTSMPPSIIQEAKSIAAKV 715

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BLAST of mutS protein homolog 4 vs. Ensembl Cavefish
Match: msh2 (mutS homolog 2 [Source:NCBI gene;Acc:103047089])

HSP 1 Score: 198.364 bits (503), Expect = 7.105e-52
Identity = 194/720 (26.94%), Postives = 325/720 (45.14%), Query Frame = 1

Query:  559 IGIASVDLKNPELELSQFSDSIGYSRTLSKLYLKDPVEIVFPHTMCENGVRSKLFQIVSEFMHKSSITTIHRRYYNDKNGKEIIQHL-----CHKDYT-SSILYESREKYYALAACAAIIKYVEFIQNILFAPGSLQIIFSGSVKCAIIDIASVRNLELVE--NSKDLTENGSLFSALNFTTTNGGYRLLRANILQPSFDIPTITSRYDCVEELMNNAELFFTLKSQI-KHFVSLNHLLSLCVQLPKN-QTVKSAENTITQVIALKHVMELIPTLRATLQSFKSSLFIEYHSLLVD-SRYDEILSI---INVVVHEDVHFEKGILQMRSQKLFAIKDGINVILDIARRSYSEQIE-----ALRDEVQALSVEHALPLRVAFSNSRGFYIQLPLTNSSVKPRLSLPFIKVAIVKNFITCTTEKIMKFNERLKGALAEIYLTAELLLSELIKAIRVHMGVLYRLSEISATLDLLLSFAQVSKMQN--YIRPEF----TDTLAIKNCRNPLLDRLSNKEAISNHV-YAANLSNFTIVTGANMSGKSMYLRQIALVQIMGQIGCFIPAEYASFRLSDHLFTRIGVDDDIQSNSSTFTIEMREMSYIINTITDNSLVLIDELGRGTSFDEGLGICFAICEHLL-QTKAFIFIATHFRELSKLEILYPNVQNVNFEVKNLSESDGDENHLLFTYKCVRGVCPDFTNAMKLAKLSNLPKQLLFEAEK 2637
            +G+  VD    ++ + +F D+  +S   + L    P E V P      G   KL Q++     +  I    R+   +   K+I+Q L       K  T SS      EK  A++  AA+IKY+E + +     GS ++      +   +D A+V+ L L +  +S D T   SL   LN   T  G RL+   + QP  D   I  R D VE  + ++EL  + +  + + F  LN L     +   N Q        + Q+  L   +E        L    ++    +  L  D S++ E++     +N + H +               F +K   +  L   R S  +Q+E     AL    + L ++    +++  +   G++ ++         R +  F  + + KN +  T  K+   NE    +  E       ++ E+I     ++  L  L+E+ A LD ++SFA VS      ++RP      +  L +K  R+P ++   +   I N V +      F I+TG NM GKS Y+RQ+ ++ +M QIGCF+P + A   + D +  R+G  D      STF  EM E + I+ + T++SL++IDELGRGTS  +G G+ +AI E++  + K+F   ATHF EL+ L    P V   N  V  L+     ++ L   Y+  +GVC D +  + +A+L+N PK ++  A +
Sbjct:  162 VGVGYVDSTLRKMGVCEFPDNDQFSNLEALLVQIGPKECVLPGGDTA-GDLGKLRQVI----QRGGILLSDRKKM-EFTAKDIVQDLNRLLKARKGETVSSAALPEMEKQIAVSCLAAVIKYLELLSDEANF-GSFKLTTFDLNQYMRLDNAAVQALNLFQGSSSDDPTGTHSLAGLLNKCRTPQGQRLVNQWLKQPLIDKNKIEERLDLVESFVEDSELRQSCQEDLLRRFPDLNRLAKKLQRQSANLQDCYRVYQAVGQLPGLVQALERHTGKHQVL--LNAAFISPFSDLTSDFSKFQEMIETTLDMNQIDHHE---------------FLVKPSFDPTLSELRESM-DQLEKSMQSALNSAARELGLDAGKTIKLESNAQMGYFFRVTCKEEK-SLRNNKKFTTLDVQKNGVRFTNSKLSSLNEEYVKSREEYEEAQNAIVKEIIGIAGGYVEPLQTLNEVIAQLDAVVSFAVVSHAAPVPFVRPRILEKGSGRLILKGSRHPCVEAQDDVAFIPNDVTFTRGEQMFHIITGPNMGGKSTYIRQVGVIVLMAQIGCFVPCDEAELSVVDCVLARVGAGDSQIKGVSTFMAEMLETAAILRSATEDSLIIIDELGRGTSTYDGFGLAWAISEYIATRLKSFCLFATHFHELTALAQQEPTV--CNLHVTALTT----DSTLTMLYRVKKGVC-DQSFGIHVAELANFPKHVIANARE 848

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BLAST of mutS protein homolog 4 vs. Ensembl Cavefish
Match: msh3 (mutS homolog 3 [Source:NCBI gene;Acc:103037699])

HSP 1 Score: 180.259 bits (456), Expect = 6.760e-46
Identity = 197/745 (26.44%), Postives = 335/745 (44.97%), Query Frame = 1

Query:  559 IGIASVDLKNPELELSQFSDSIGYSRTLSKLYLKDPVEIVFPHTMCENGVRSKLFQIVS------------------EFMHKSSITTIHRRYYNDKNGKEIIQHLCHKDYTSSILYESREKYYALAACAAIIKYV-EF-IQNILFAPGSLQIIFSGSVKCAIIDIASVRNLELVENSKDLTENGSLFSALNFTTTNGGYRLLRANILQPSFDIPTITSRYDCVEELMNNAELFFTLKSQIKHFVSLNHLLSLCVQLPKNQTVKSAENTITQVIALKHVMELIPTLRATLQSFKSSLFIEYHSLLVDSRYDEILSIINVVVHED----VHFEKGILQMRSQKLFAIKDGINVILDIARRSYSEQIEALRDEVQAL---SVEHALPLRVAFSN---------SRGFYIQLPLTNSSVKPRLSLPFIKVAIVKN----FITCTTEKIMKFNERLKGALAEIYLTAELLLSELIKAIRVHMGVLYRLSEISATLDLLLSFAQVSKMQNYIRPEFTDT---LAIKNCRNPLLDRLSNKE---AISNHVYAANLSNFTIVTGANMSGKSMYLRQIALVQIMGQIGCFIPAEYASFRLSDHLFTRIGVDDDIQSNSSTFTIEMREMSYIINTITDNSLVLIDELGRGTSFDEGLGICFAICEHLLQ-TKAFIFIATHFRELSKLEILYP-NVQNVNFE-VKNLSESDGDENH-----LLFTYKCVRGVCPDFTNAMKLAKLSNLPKQLLFEA 2631
            +G+  V     ++ L  F D+   S   +++    PVEI+ P  + E   R  L + ++                  +F + +++ T+ R +Y  ++ + +    C K   S+  Y S E    +     +I+Y+ EF ++ +L  P S + + S S    ++   +++NLE+  N    +  GSL   L+ T T  G RLL+  + QP      I SR + V E+         L S+     S+  LL+   +LP        E  +  +   K   +    L +TL    S L IE+ +L + +   +I S +   +  D    +      L++ ++      +   +  D+        IE  +D++Q +    +EH   LR+   N          + F I++  + SSV P   +      +V      FI      +++  E+L     + ++    L  E    ++  +G L       AT+D   S AQV+K  NY RPE  +    + I++ R+P++D L  ++     ++     +     IVTG NM GKS Y+RQ+ALV IM Q+G F+PA  AS  + D +FTR+G  D+I    STF  E+ E S I++  T  SLV++DELGRGTS  +G+ I +A  E  ++  K      TH+  L +LE LYP +V N +   + N  E  GDE       + F Y+   G     +  + +A+L+N+P+ +L  A
Sbjct:  368 VGLVVVQPSTGDVMLDCFKDNTSRSELEARVLKIQPVEILVPSDLSEPTER--LLRTIALSSVQADDRIRIEKRESTQFEYPTAMMTV-REFYTSRSTRTVKN--CEKG--SASFYLSLESP-VICCLGPVIQYLTEFKLERVLLCPSSFRRLLSDS-DHMVLSATTMKNLEIFCNQTTGSVKGSLLWVLDHTHTPFGKRLLKKWVSQPLKSASEILSRQEAVAEI---------LSSESSVLPSIQALLN---RLP------DLERGLCSIYHKKCSTQEFYLLSSTL----SRLGIEFQAL-IPAVQSQISSALLKSLLLDTPQLLSPAHNFLKVLNENAAKTGNKTELFADLTDFPV---IEQRKDQIQNILSDIMEHRRELRLILRNPSLNYATVSGQEFLIEVKNSMSSVVPPDWVKINSTKVVGRYHSPFIVEKYRCLLQLREQLVIDSGQEWINFLQLFGEHYYILKKAVGHL-------ATMDCFFSLAQVAKENNYCRPEVLEQERHIVIRDGRHPVIDMLMGEQDQYVPNDTELQGDGKRAMIVTGPNMGGKSSYIRQVALVTIMAQLGSFVPAREASIGMVDGIFTRMGASDNISRGRSTFMEELLEASEILSHATSRSLVILDELGRGTSTHDGIAIAYATLEFFIRDVKCLTLFVTHYPPLCELEKLYPLHVGNYHMAFLLNEPEIVGDEEEVQPEFITFLYQLTEGAA-GRSYGLNVARLANIPESILRTA 1069

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Query:  559 IGIASVDLKNPELELSQFSDSIGYSRTLSKLYLKDPVEIVFPHTMCENGVRSKLFQIVS------------------EFMHKSSITTIHRRYYNDKNGKEIIQHLCHKDYTSSILYESREKYYALAACAAIIKYV-EF-IQNILFAPGSLQIIFSGSVKCAIIDIASVRNLELVENSKDLTENGSLFSALNFTTTNGGYRLLRANILQPSFDIPTITSRYDCVEELMNNAELFFTLKSQIKHFVSLNHLLSLCVQLPKNQTVKSAENTITQVIALKHVMELIPTLRATLQSFKSSLFIEYHSLLVDSRYDEILSIINVVVHED----VHFEKGILQMRSQKLFAIKDGINVILDIARRSYSEQIEALRDEVQAL---SVEHALPLRVAFSN---------SRGFYIQLPLTNSSVKPRLSLPFIKVAIVKN----FITCTTEKIMKFNERLKGALAEIYLTAELLLSELIKAIRVHMGVLYRLSEISATLDLLLSFAQVSKMQNYIRPEFTDT---LAIKNCRNPLLDRLSNKE---AISNHVYAANLSNFTIVTGANMSGKSMYLRQIALVQIMGQIGCFIPAEYASFRLSDHLFTRIGVDDDIQSNSSTFTIEMREMSYIINTITDNSLVLIDELGRGTSFDEGLGICFAICEHLLQ-TKAFIFIATHFRELSKLEILYP-NVQNVNFE-VKNLSESDGDENH-----LLFTYKCVRGVCPDFTNAMKLAKLSNLPKQLLFEA 2631
            +G+  V     ++ L  F D+   S   +++    PVEI+ P  + E   R  L + ++                  +F + +++ T+ R +Y  ++ + +    C K   S+  Y S E    +     +I+Y+ EF ++ +L  P S + + S S    ++   +++NLE+  N    +  GSL   L+ T T  G RLL+  + QP      I SR + V E+         L S+     S+  LL+   +LP        E  +  +   K   +    L +TL    S L IE+ +L + +   +I S +   +  D    +      L++ ++      +   +  D+        IE  +D++Q +    +EH   LR+   N          + F I++  + SSV P   +      +V      FI      +++  E+L     + ++    L  E    ++  +G L       AT+D   S AQV+K  NY RPE  +    + I++ R+P++D L  ++     ++     +     IVTG NM GKS Y+RQ+ALV IM Q+G F+PA  AS  + D +FTR+G  D+I    STF  E+ E S I++  T  SLV++DELGRGTS  +G+ I +A  E  ++  K      TH+  L +LE LYP +V N +   + N  E  GDE       + F Y+   G     +  + +A+L+N+P+ +L  A
Sbjct:  368 VGLVVVQPSTGDVMLDCFKDNTSRSELEARVLKIQPVEILVPSDLSEPTER--LLRTIALSSVQADDRIRIEKRESTQFEYPTAMMTV-REFYTSRSTRTVKN--CEKG--SASFYLSLESP-VICCLGPVIQYLTEFKLERVLLCPSSFRRLLSDS-DHMVLSATTMKNLEIFCNQTTGSVKGSLLWVLDHTHTPFGKRLLKKWVSQPLKSASEILSRQEAVAEI---------LSSESSVLPSIQALLN---RLP------DLERGLCSIYHKKCSTQEFYLLSSTL----SRLGIEFQAL-IPAVQSQISSALLKSLLLDTPQLLSPAHNFLKVLNENAAKTGNKTELFADLTDFPV---IEQRKDQIQNILSDIMEHRRELRLILRNPSLNYATVSGQEFLIEVKNSMSSVVPPDWVKINSTKVVGRYHSPFIVEKYRCLLQLREQLVIDSGQEWINFLQLFGEHYYILKKAVGHL-------ATMDCFFSLAQVAKENNYCRPEVLEQERHIVIRDGRHPVIDMLMGEQDQYVPNDTELQGDGKRAMIVTGPNMGGKSSYIRQVALVTIMAQLGSFVPAREASIGMVDGIFTRMGASDNISRGRSTFMEELLEASEILSHATSRSLVILDELGRGTSTHDGIAIAYATLEFFIRDVKCLTLFVTHYPPLCELEKLYPLHVGNYHMAFLLNEPEIVGDEEEVQPEFITFLYQLTEGAA-GRSYGLNVARLANIPESILRTA 1069

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BLAST of mutS protein homolog 4 vs. Ensembl Cavefish
Match: msh3 (mutS homolog 3 [Source:NCBI gene;Acc:103037699])

HSP 1 Score: 142.895 bits (359), Expect = 3.413e-34
Identity = 87/242 (35.95%), Postives = 135/242 (55.79%), Query Frame = 1

Query: 1948 NYIRPEFTDT---LAIKNCRNPLLDRLSNKE---AISNHVYAANLSNFTIVTGANMSGKSMYLRQIALVQIMGQIGCFIPAEYASFRLSDHLFTRIGVDDDIQSNSSTFTIEMREMSYIINTITDNSLVLIDELGRGTSFDEGLGICFAICEHLLQ-TKAFIFIATHFRELSKLEILYP-NVQNVNFE-VKNLSESDGDENH-----LLFTYKCVRGVCPDFTNAMKLAKLSNLPKQLLFEA 2631
            N+++PE  +    + I++ R+P++D L  ++     ++     +     IVTG NM GKS Y+RQ+ALV IM Q+G F+PA  AS  + D +FTR+G  D+I    STF  E+ E S I++  T  SLV++DELGRGTS  +G+ I +A  E  ++  K      TH+  L +LE LYP +V N +   + N  E  GDE       + F Y+   G     +  + +A+L+N+P+ +L  A
Sbjct:  793 NFLQPEVLEQERHIVIRDGRHPVIDMLMGEQDQYVPNDTELQGDGKRAMIVTGPNMGGKSSYIRQVALVTIMAQLGSFVPAREASIGMVDGIFTRMGASDNISRGRSTFMEELLEASEILSHATSRSLVILDELGRGTSTHDGIAIAYATLEFFIRDVKCLTLFVTHYPPLCELEKLYPLHVGNYHMAFLLNEPEIVGDEEEVQPEFITFLYQLTEGAA-GRSYGLNVARLANIPESILRTA 1033

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BLAST of mutS protein homolog 4 vs. Ensembl Sea Lamprey
Match: msh3 (mutS homolog 3 (E. coli) [Source:ZFIN;Acc:ZDB-GENE-060526-307])

HSP 1 Score: 165.622 bits (418), Expect = 3.962e-42
Identity = 191/754 (25.33%), Postives = 338/754 (44.83%), Query Frame = 1

Query:  562 GIASVDLKNPELELSQFSDSIGYSRTLSKLYLKDPVEIVFPHTMCENGVRS---------------KLFQI-VSEFMHKSSITTIHRRYYNDKNGKEIIQHLCHKDYTSSILYESREKYYALAAC-AAIIKYV-EF-IQNILFAPGSLQIIFSGSVKCAIIDIASVRNLELVENSKDLTENGSLFSALNFTTTNGGYRLLRANILQPSFDIPTITSRYDCVEELMNNAELFFTLKSQIKHFVSLNHLLSLCVQLPKNQTVKSAENTITQVIALKHVMELIPTLRATLQSFKSSLFIEYHSLLVDSRYDEILSIINVVVHEDV--------HFEKGILQMRSQ-----KLFAIKDGINVILDIARRSYSEQIEALRDEVQALSVEHALPLRVAFSNSRGFYIQLPLTNSSVKPRLSL----P--FIKVAIVKN-------FITCTTEKIMKFNERLKGALAEIYLTAELLLSELIKAIRVHMGVLYRLSEISATLDLLLSFAQVSKMQNY--IRPEFTDT---LAIKNCRNPLLDRL--SNKEAISNHVY-AANLSNFTIVTGANMSGKSMYLRQIALVQIMGQIGCFIPAEYASFRLSDHLFTRIGVDDDIQSNSSTFTIEMREMSYIINTITDNSLVLIDELGRGTSFDEGLGICFAICEHLL-QTKAFIFIATHFRELSKLEILYPNV---QNVNFEVKNLSES----DGDE-NHLLFTYKCVRGVCPDFTNAMKLAKLSNLPKQLLFEAEK 2637
            G+ +V     EL    F D        S++    PVE++ P  + +   RS               ++ ++ V  F H  +   + R +     G E +Q  C+ D        + EK   + AC A +I Y+ EF ++ +L+   + Q  FS   +C  I+  + +N+EL +N  +    GSL  A++ T T  G R+ R  + +P   I  I +R DCV E++ +           +H V L+    L  +LP        E  +T +   K   +    + ++L+     L  E H+L   ++ D++ S + + +  DV        H+ + + +  ++     +LF    G   +L   RRS  E+I A+ +E++    EH   +R    +    Y  +      ++ R S+    P  ++K+   K        F+    +++ +  E+L+      +L       E     R  +  L       ATLD L S A ++    Y  IRPEF +    + I+N R+P+++ L     + + N  +  A+     I+TG NM GKS Y+RQ+AL+ +M Q+G F+PA +A       + TR+G  D+I    STF  E+ E S II   T +SLV++DELGRGTS  +G+ I +A  E+ + + +      TH+  + ++E L   V    +++F +    E+    DG+    + F Y+   G     +  + +A+L+ +P+Q+L  A +
Sbjct:  185 GLVAVQPSTGELLFDCFEDGKARLELESRVLSLQPVELLIPAALSDETERSLCSLTANSSQGDDRVRVERVDVDLFEHSRAFQAVSRFF-----GAESLQSNCNHDEQKLSHVLAMEK--PIIACLAVLIHYLTEFGLERVLYLSSNFQK-FSMESECLHINGITQKNMELFQNQTNGKVKGSLLWAMDRTCTPFGRRMFRNWLGRPLISISDINARLDCVSEILAS-----------EHMV-LSRAKELLWKLP------DLERGLTSIYHRKCSTKEFSLIASSLER----LCTETHALAASAQ-DQLSSPLLLGILLDVPRRLQHVQHYTRVLDKQAAKEGDKTRLFTDLTGFPRML---RRS--EEIRAVLEELR----EHRTEVRRTLRSPAADYTTVSGQEFLIEVRNSMLHTVPSNWVKIGSTKAVTRFHTPFVVQKFKQLCQLREKLRIDSNAEWLGFLTQFGEHYHNFRAAVAQL-------ATLDCLFSLAAIASRDGYCSIRPEFVEEKSLIVIENGRHPVVELLMGDQNQYVPNSTHLDADGKRAMIITGPNMGGKSSYIRQVALIAVMAQMGSFVPASHAKLSSLHAIHTRMGASDNIYKGHSTFMEELSEASEIIRKATRHSLVILDELGRGTSTHDGIAIAYATLEYFVKEVQCLTLFVTHYPPVCEMERLNAEVVSNYHMSFLLSEPEETAQGEDGERLESVTFLYQLTEGPAAR-SYGLNVARLAAIPEQVLHTAAQ 890

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BLAST of mutS protein homolog 4 vs. Ensembl Sea Lamprey
Match: msh6 (mutS homolog 6 (E. coli) [Source:ZFIN;Acc:ZDB-GENE-020905-3])

HSP 1 Score: 112.079 bits (279), Expect = 3.139e-25
Identity = 68/197 (34.52%), Postives = 103/197 (52.28%), Query Frame = 1

Query: 2077 IVTGANMSGKSMYLRQIALVQIMGQIGCFIPAEYASFRLSDHLFTRIGVDDDIQS-----NSSTFTIEMREMSYIINTITDNSLVLIDEL-------GRGTSFDEGLGICFAICEHLLQ-TKAFIFIATHFRELSKLEILYPNVQ--NVNFEVKNLSESDGDENHLLFTYKCVRGVCPDFTNAMKLAKLSNLPKQLL 2622
            +VTG NM GKS  +RQ  L+ IM Q+GC++PAE       D +FTR+G  D I S       STF +E+ E S I+   T +SLVL+DEL       GRGT+  +G  I  A+   L +  +     +TH+  L +     P+V+  ++   V+  ++ D  +  + F YK V G CP  +     A+L+ LP  ++
Sbjct: 1162 LVTGPNMGGKSTLMRQAGLIVIMAQLGCYVPAEACRLTPVDRVFTRLGASDRIMSVLRRAGESTFFVELSETSSILQHATRHSLVLLDELGFLLRPRGRGTATYDGTAIASAVVHELAEGVRCRTLFSTHYHSLVEDFAASPHVRLGHMACMVEQENDDDPSQETITFLYKFVAGACPK-SYGFNAARLAGLPDAVV 1357

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BLAST of mutS protein homolog 4 vs. Ensembl Sea Lamprey
Match: msh2 (mutS homolog 2 (E. coli) [Source:ZFIN;Acc:ZDB-GENE-040426-2932])

HSP 1 Score: 50.0618 bits (118), Expect = 1.744e-6
Identity = 63/220 (28.64%), Postives = 93/220 (42.27%), Query Frame = 1

Query:  529 IEGRGV-ASGEIGIASVDLKNPELELSQFSDSIGYSRTLSKLYLKDPVEIVFPHTMCENGVRSKLFQIVSEFMHKSSITTIHRRYYNDKNGKEIIQHLCH------KDYTSSILYESREKYYALAACAAIIKYVEFIQN-ILFAPGSLQIIFSGSVKCAIIDIASVRNLELVENSKDLTENG---SLFSALNFTTTNGGYRLLRANILQPSFDIPTITSR 1155
            I+G G  A   +G+   D     L + +F D+  +S   + L    P E V P    +     KL Q+V     +S +    R+   + + K+I+Q L         +  +S      EK  A+++ AA++KY+E   +   F    L     G  +   +D A+VR L L + S D  E G   SLF  LN   T  G RLL   I QP  D   I  R
Sbjct:  150 IQGGGADAQRVVGVGFADTTLRRLCVCEFPDNDQFSNLEALLVQLGPKECVLPAGEVQADA-GKLRQVV----QRSGLLITDRKKV-EFSSKDIVQDLNRLLKTRKGEQANSAALSEMEKQVAMSSLAALVKYLELTSDESGFGQFELSTFDLG--QYVRLDSAAVRALNLFQGSSD--EGGRTQSLFGLLNRCRTAQGQRLLAQWIKQPLLDQNRIEER 359

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BLAST of mutS protein homolog 4 vs. Ensembl Yeast
Match: MSH4 (Protein involved in meiotic recombination; required for normal levels of crossing over, colocalizes with Zip2p to discrete foci on meiotic chromosomes, has homology to bacterial MutS protein [Source:SGD;Acc:S000001891])

HSP 1 Score: 328.946 bits (842), Expect = 1.406e-98
Identity = 229/684 (33.48%), Postives = 367/684 (53.65%), Query Frame = 1

Query:  520 CLLIEGRGVASGEIGIASVDLKNPELELSQFSDSIGYSRTLSKLYLKDPVEIVFPHTMCENGVRSKLFQIVSEFMHKSSITTIHRRYYNDKNGKEIIQHLCHKDYTSSI-LYESREKYYALAACAAIIKYVEFI----QNILFAPGSLQIIFSGSVKCAIIDIASVRNLELVENSKDLTENG-SLFSALNFTTTNGGYRLLRANILQPSFDIPTITSRYDCVEELMNNAELFFTLKSQIKHFVSLNHLLS--LCVQLPKNQTVKSAENTITQVIALKHVMELIPTLRATL--QSFKSSLFIEYHSLLVDSRYDEILSIINVVVHEDVHFEKGILQMRSQKLFAIKDGINVILDIARRSYSEQIEALRDEVQALSVEHALPLRVAFSNSRGFYIQLPLTNSSVKPRLSLP--FIKVAIVKNFITCTTEKIMKFNERLKGALAEIYLTAELLLSELIKAIRVHMGVLYRLSEISATLDLLLSFAQVSKMQNYIRPEFTDTLAIKNCRNPLLDRLSNKEAISNHVYAA-NLSNFTIVTGANMSGKSMYLRQIALVQIMGQIGCFIPAEYASFRLSDHLFTRIGVDDDIQSNSSTFTIEMREMSYIINTITDNSLVLIDELGRGTSFDEGLGICFAICEHLLQTKAFIFIATHFRELSKLEILYPNVQNVNFEVKNLSESDGDENHLL 2532
            C + E     S  IG+  ++    ++ LS F DS  Y R + KL +  P EI+ P +     V      I         I    R+ +N ++G   I      D    + + E  +K +AL A +A I Y+E I       L A   L+I F G+    +ID  +VR LELVEN  D  +NG SL+  L+ T+T  G R LR +ILQP  D  +I  R + +EEL  N +L   L+ ++K    L+ L S  LC+    N +    +  I  V+ LK  ++ + +L+  L  Q  +S L  E   +  +    EI  +IN  ++ED  +    +Q+ +Q+ +A+K   N +LD++R+ Y E  E    EV+ L+ ++ + L   + ++RGFY+++           +LP  FI   I KN+I CTT  I+K N RLK  + EI L +E  + EL+  I  H+  L+ ++E  A LDL+ SF    K  NY  P FT+ L I++ R+PLL+++  K  + N + +  + S+  I+TG NMSGKS+YL+Q+AL+ IM Q+G  IPA Y SF +   L  R+  +D ++  SS F  EM+EM+Y ++ I   +L+++DELGRG+S  +G  +  A+ EHLL+T+A +F++THF+++ K+    P V +++ +   L+++    N+ L
Sbjct:  107 CCIYEVPRDISTRIGLCIINCNTGQMYLSDFMDSQIYIRVVHKLQIYQPTEILIPSSSLAPTVSKLATMIKFNVAETVKIEEGSRKCFNSQDGLAAITKYLMDDTKKDLKIEEIIDKTFALCAASAAISYMEEIISKSSRNLNAFRKLRIQFEGTENTMLIDSKTVRGLELVENKLD--KNGISLWKFLDTTSTKMGQRSLRNSILQPLTDRGSIEMRLEALEELKANDDLLQKLRLEMKSLPDLDKLFSRLLCI----NHSAIKPDQRINYVLLLKETLQSVKSLKDALNDQLIQSRLISETKKIFNNDAIMEIEKLINSCINEDCVWASSAIQLLNQRSYAVKSDSNGLLDVSRQIYKEVKEEFFREVEDLTAKNKINLDHNYDSARGFYLRIK-RQEFTDDVATLPDVFISRTIKKNYIECTTLNIIKKNARLKEVMEEILLLSEETVDELLDKIATHISELFMIAEAVAILDLVCSFTYNLKENNYTIPIFTNNLLIRDSRHPLLEKVL-KNFVPNTISSTKHSSSLQIITGCNMSGKSVYLKQVALICIMAQMGSGIPALYGSFPVFKRLHARV-CNDSMELTSSNFGFEMKEMAYFLDDINTETLLILDELGRGSSIADGFCVSLAVTEHLLRTEATVFLSTHFQDIPKIMSKKPAVSHLHMDAVLLNDNSVKMNYQL 781

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BLAST of mutS protein homolog 4 vs. Ensembl Yeast
Match: MSH2 (Protein that binds to DNA mismatches; forms heterodimers with Msh3p and Msh6p that bind to DNA mismatches to initiate the mismatch repair process; contains a Walker ATP-binding motif required for repair activity and involved in interstrand cross-link repair; Msh2p-Msh6p binds to and hydrolyzes ATP [Source:SGD;Acc:S000005450])

HSP 1 Score: 184.496 bits (467), Expect = 2.830e-48
Identity = 159/564 (28.19%), Postives = 262/564 (46.45%), Query Frame = 1

Query: 1051 SLFSALNFTTTNGGYRLLRANILQPSFDIPTITSRYDCVEELMNNAELFFTLKSQIKHFVSLNHLLSLCVQLPKNQTVKSAENTITQVIALKHVMELIPTLRATLQSF--------KSSLFIEYHSLLVDSRYDEILSIINVVVHEDVHFEKGILQMRSQKLFAIKDGINVILDIARRSYSEQIEALRDEVQALSVEHALPL------RVAFSNSR--GFYIQLPLTNSSVKPRLSLPFIKVAIVKNFITCTTEKIMKFNERLKGALAEIYLTAELLLSELIKAIRVHMGVLYRLSEISATLDLLLSFAQVSKMQN--YIRPEFTDTLAIK-----NCRNPLLDRLSNKEAISNHV-YAANLSNFTIVTGANMSGKSMYLRQIALVQIMGQIGCFIPAEYASFRLSDHLFTRIGVDDDIQSNSSTFTIEMREMSYIINTITDNSLVLIDELGRGTSFDEGLGICFAICEHLL-QTKAFIFIATHFRELSKLEILYPNVQNVNFEV---KNLSESDGDENHLLFTYKCVRGVCPDFTNAMKLAKLSNLPKQLLFEAEKIYGRLGD 2658
            SLF  LN   TN G RLL   + QP  +I  I  R+D V+ L++  EL   L S+  +   +  +  L  +L K          +  V+ +    + IP +     SF          +  +    L   S + E LS    +V   V  +           F IK   N  L   R     +++ LRDE+ ++ ++ A  L      ++   N    G+ ++L   N + + R    +I+++ VK  I  +T+++            E       L+ E+I     +  V  +LS + A LD++ SFA  S      YIRP+     + +     + R+P+L+   +   ISN V   +   +F I+TG NM GKS Y+RQ+ ++ +M QIGCF+P E A   + D +  R+G  D      STF +E+ E + I+   + NSL+++DELGRGTS  +G G+ +AI EH+  +   F   ATHF EL++L    PNV+N++      KNL E   D+  +   YK   G+  D +  + +A++   P++++  A++    L D
Sbjct:  337 SLFQLLNHCKTNAGVRLLNEWLKQPLTNIDEINKRHDLVDYLIDQIELRQMLTSE--YLPMIPDIRRLTKKLNK-------RGNLEDVLKIYQFSKRIPEIVQVFTSFLEDDSPTEPVNELVRSVWLAPLSHHVEPLSKFEEMVETTVDLD----AYEENNEFMIKVEFNEELGKIRS----KLDTLRDEIHSIHLDSAEDLGFDPDKKLKLENHHLHGWCMRL-TRNDAKELRKHKKYIELSTVKAGIFFSTKQLKSIANETNILQKEYDKQQSALVREIINITLTYTPVFEKLSLVLAHLDVIASFAHTSSYAPIPYIRPKLHPMDSERRTHLISSRHPVLEMQDDISFISNDVTLESGKGDFLIITGPNMGGKSTYIRQVGVISLMAQIGCFVPCEEAEIAIVDAILCRVGAGDSQLKGVSTFMVEILETASILKNASKNSLIIVDELGRGTSTYDGFGLAWAIAEHIASKIGCFALFATHFHELTELSEKLPNVKNMHVVAHIEKNLKEQKHDDEDITLLYKVEPGIS-DQSFGIHVAEVVQFPEKIVKMAKRKANELDD 881

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BLAST of mutS protein homolog 4 vs. Ensembl Yeast
Match: MSH3 (Mismatch repair protein; forms dimers with Msh2p that mediate repair of insertion or deletion mutations and removal of nonhomologous DNA ends, contains a PCNA (Pol30p) binding motif required for genome stability [Source:SGD;Acc:S000000688])

HSP 1 Score: 184.496 bits (467), Expect = 3.431e-48
Identity = 161/555 (29.01%), Postives = 267/555 (48.11%), Query Frame = 1

Query: 1048 GSLFSALNFTTTNGGYRLLRANILQPSFDIPTITSRYD---CVEELMNNAELFFTLKSQIKHFVSLNHLLSLCVQLPKNQTVKSAENTITQVIALKHVMELIPTLRATL----QSFKSS-------------LFIEYHSLLVDSRYDEILSIINVVVHEDVHFEKGILQMRSQKLFAIKDGINVILDIARRSYSEQIEALRDEVQALSVEHALPLRVAFSNSRGFYIQLPLTNSSVKPRLSLP--FIKVAIVKNFITCTTEKIMKFNERLKGALAEIYLTAELLLSELIKAIRVHMGVLYRLSEISATLDLLLSFAQVSKMQNYIRPEFTD---TLAIKNCRNPLLDRLSNKEAISNHVYAANLSNFTIVTGANMSGKSMYLRQIALVQIMGQIGCFIPAEYASFRLSDHLFTRIGVDDDIQSNSSTFTIEMREMSYIINTITDNSLVLIDELGRGTSFDEGLGICFAICEHL--LQTKAFIFIATHFRELSKLEILYPNVQNVNFEVKNLSESDGDENHLLFTYKCVRGVCPDFTNAMKLAKLSNLPKQLLFEA 2631
            GSLF  L+ T T+ G R+LR  IL+P  D+  I  R D   C+   +NN+ +FF   +Q+     LNH   L   L  N+ +    +       LK +   +   +       + FKSS             LF E + LL  ++    L++INV    + + +K ++   +   +   +GI   + I R S S + + L++E+  +      P  + F +   + I++   NS +K    LP  +IKV   K     TT +  K  ++L+     +   +EL   E +  I      L +++   A  D +LS A  S   NY+RP F +    +  KN RNP+++ L      ++ + +       I+TG NM GKS Y+RQ+AL+ IM QIG F+PAE     + +++ TRIG  DDI +  STF +EM ++ +I+      SL+L+DE+GRGT   +G+ I +A+ ++   L     I   THF  L   EI  P ++N + +     ++  D   ++F YK  +G+  + +  M +AKL+ L K ++  A
Sbjct:  438 GSLFWLLDHTRTSFGLRMLREWILKPLVDVHQIEERLDAIECITSEINNS-IFFESLNQM-----LNHTPDLLRTL--NRIMYGTTSRKEVYFYLKQITSFVDHFKMHQSYLSEHFKSSDGRIGKQSPLLFRLFSELNELLSTTQLPHFLTMINVSAVMEKNSDKQVMDFFNLNNYDCSEGI---IKIQRESESVRSQ-LKEELAEIRKYLKRPY-LNFRDEVDYLIEV--KNSQIK---DLPDDWIKVNNTKMVSRFTTPRTQKLTQKLEYYKDLLIRESELQYKEFLNKITAEYTELRKITLNLAQYDCILSLAATSCNVNYVRPTFVNGQQAIIAKNARNPIIESLDVHYVPNDIMMSPENGKINIITGPNMGGKSSYIRQVALLTIMAQIGSFVPAEEIRLSIFENVLTRIGAHDDIINGDSTFKVEMLDILHILKNCNKRSLLLLDEVGRGTGTHDGIAISYALIKYFSELSDCPLILFTTHFPMLG--EIKSPLIRNYHMDYVEEQKTGEDWMSVIFLYKLKKGLTYN-SYGMNVAKLARLDKDIINRA 971

[Close]

BLAST of mutS protein homolog 4 vs. Ensembl Yeast
Match: MSH1 (DNA-binding protein of the mitochondria; involved in repair of mitochondrial DNA; has ATPase activity and binds to DNA mismatches; has homology to E. coli MutS; transcription is induced during meiosis [Source:SGD;Acc:S000001162])

HSP 1 Score: 139.813 bits (351), Expect = 3.078e-34
Identity = 88/259 (33.98%), Postives = 147/259 (56.76%), Query Frame = 1

Query: 1906 LDLLLSFAQVSKMQNYIRPEFTDT--LAIKNCRNPLLDRLSNKEAISNHVYAAN-----LSNFTIVTGANMSGKSMYLRQIALVQIMGQIGCFIPAEYASFRLSDHLFTRIGVDDDIQSNSSTFTIEMREMSYIINTITDNSLVLIDELGRGTSFDEGLGICFAICEHLLQ-TKAFIFIATHF-RELSKL---EILYPNVQNVNFEVKNLSESDGDENHLLFTYKCVRGVCPDFTNAMKLAKLSNLPKQLLFEAEKIYG 2646
            LD L SFA ++  +N + P+  ++  L + N R+ +++      A S   + AN       N  ++TG NM GKS +LRQ A++ I+ QIGCF+P   A   + D LF+R+G  DD+ +  STF +EM E S+I+   T+ SL ++DE+GRGTS  EG+ I +A  ++LL+  +     ATHF +EL ++   +      + V F    +++  G  N+  + +K   G+C   ++A+++A+L+  P + L EA +I G
Sbjct:  706 LDTLSSFAVLANERNLVCPKVDESNKLEVVNGRHLMVE--EGLSARSLETFTANNCELAKDNLWVITGPNMGGKSTFLRQNAIIVILAQIGCFVPCSKARVGIVDKLFSRVGSADDLYNEMSTFMVEMIETSFILQGATERSLAILDEIGRGTSGKEGISIAYATLKYLLENNQCRTLFATHFGQELKQIIDNKCSKGMSEKVKFYQSGITDLGG--NNFCYNHKLKPGICTK-SDAIRVAELAGFPMEALKEAREILG 959

[Close]

BLAST of mutS protein homolog 4 vs. Ensembl Yeast
Match: MSH6 (Protein required for mismatch repair in mitosis and meiosis; forms a complex with Msh2p to repair both single-base & insertion-deletion mispairs; also involved in interstrand cross-link repair; potentially phosphorylated by Cdc28p [Source:SGD;Acc:S000002504])

HSP 1 Score: 134.035 bits (336), Expect = 2.753e-32
Identity = 172/746 (23.06%), Postives = 331/746 (44.37%), Query Frame = 1

Query:  562 GIASVDLKNPELELSQFSDSIGYSRTLSKLYLKDPVEIVFPHTMCENGVRSKLFQIVSEFMHKSSI---TTIHRRYYN-DKNGKEII--QHLCHKDYTSSIL---YESREK--YYALAACAAIIKYVEFIQNILFAPGSLQIIFSGSVKCAIIDIASVRNLELVENSKDLTENGSLFSALNFTTTNGGYRLLRANILQPSFDIPTITSRYDCVEELMNNAELFFTLKSQIK-HFVSLNHLLSLCVQL-PKNQTVKSAENTITQVIALKHVMELIPTLRAT-LQSFKSSLFIEYHSLLVDSRYDEILSIINVVVHEDVHFEKGILQMRSQKLFAIKDGINVILDIARRSYSEQIEALRDEVQALSVEHALPLRVAF-----SNSRGFYIQLPLTNSSVKPRLSLPFIKVAIVKNFITCTTEKIMKFNERLKGALAEIYLT-AELLLSELIKAIRVHMGVLYRLSEISA--TLDLLLSFAQVSKM--QNYIRPEFTDT------------LAIKNCRNPL--LDRLSNKEAISNHV-YAANLSNFTIVTGANMSGKSMYLRQIALVQIMGQIGCFIPAEYASFRLSDHLFTRIGVDDDIQSNSSTFTIEMREMSYIINTITDNSLVLIDELGRGTSFDEGLGICFAICEHL-LQTKAFIFIATHFRELSKLEILYPNVQNVNFEVKNLSESDGDENHLLFTYKCVRGVCPDFTNAMKLAKLSNLPKQLLFEAEKIYGRLGDSNELIIE 2679
            G A +D    EL++ +F D    ++  + +    P+E+V    M  N + +   +IV      ++I         +Y+ DK   EII  ++   ++    +L   Y++ +K  + A       +K+++  +N++      +  F  S    ++D  +++NLE+  NS D ++ G+LF   N   T  G R+++  ++ P      I SR D V+ L+ +     TL+ Q++  F  L  L  +  ++  +   VK  E  IT   A + ++EL  +L+   L+   S     +   LV++    + S  N    +    E  I+  R         G ++  D +     ++I+ L DE+  + + +    + +      S    + I++P++ +   P     ++++A  K +    ++++      +  A  EI+ T  E L + L +    H   ++ +  I A   +D LL+  + S+       RP   D             L  K+ R+P   L   + K+ I N +          ++TGAN +GKS  LR   +  IM Q+GC++P E A     D + TR+G +D+I    STF +E+ E   I++  T+ SL+++DELGRG S  +G  I  ++  H+    ++  F ATH+  L+     +P V+ +   +      D    ++ F YK + G   + +  M +A +  + K+++  A+     L  ++ L+ E
Sbjct:  468 GAAFIDTATGELQMLEFEDDSECTKLDTLMSQVRPMEVV----MERNNLSTLANKIVKFNSAPNAIFNEVKAGEEFYDCDKTYAEIISSEYFSTEEDWPEVLKSYYDTGKKVGFSAFGGLLYYLKWLKLDKNLISMKNIKEYDFVKSQHSMVLDGITLQNLEIFSNSFDGSDKGTLFKLFNRAITPMGKRMMKKWLMHPLLRKNDIESRLDSVDSLLQD----ITLREQLEITFSKLPDLERMLARIHSRTIKVKDFEKVIT---AFETIIELQDSLKNNDLKGDVSKYISSFPEGLVEA----VKSWTNAFERQKAINENIIVPQR---------GFDIEFDKSM----DRIQELEDELMEILMTYRKQFKCSNIQYKDSGKEIYTIEIPISATKNVPS---NWVQMAANKTYKRYYSDEVRALARSMAEA-KEIHKTLEEDLKNRLCQKFDAHYNTIW-MPTIQAISNIDCLLAITRTSEYLGAPSCRPTIVDEVDSKTNTQLNGFLKFKSLRHPCFNLGATTAKDFIPNDIELGKEQPRLGLLTGANAAGKSTILRMACIAVIMAQMGCYVPCESAVLTPIDRIMTRLGANDNIMQGKSTFFVELAETKKILDMATNRSLLVVDELGRGGSSSDGFAIAESVLHHVATHIQSLGFFATHYGTLASSFKHHPQVRPLKMSIL----VDEATRNVTFLYKMLEGQS-EGSFGMHVASMCGISKEIIDNAQIAADNLEHTSRLVKE 1175

[Close]

BLAST of mutS protein homolog 4 vs. Ensembl Nematostella
Match: EDO35291 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SM04])

HSP 1 Score: 664.455 bits (1713), Expect = 0.000e+0
Identity = 325/713 (45.58%), Postives = 489/713 (68.58%), Query Frame = 1

Query:  526 LIEGRGVASGEIGIASVDLKNPELELSQFSDSIGYSRTLSKLYLKDPVEIVFPHTMCENGVRSKLFQIVSEFMHKSSITTIHRRYYNDKNGKEIIQHLCHKDYTSSILYESREKYYALAACAAIIKYVEFIQNILFAPGSLQIIFSGSVKCAIIDIASVRNLELVENSKDLTENGSLFSALNFTTTNGGYRLLRANILQPSFDIPTITSRYDCVEELMNNAELFFTLKSQIKHFVSLNHLLSLCVQLPKNQTVKSAENTITQVIALKHVMELIPTLRATLQSFKSSLFIEYHSLLVDSRYDEILSIINVVVHEDVHFEKGILQMRSQKLFAIKDGINV--------------------ILDIARRSYSEQIEALRDEVQALSVEHALPLRVAFSNSRGFYIQLPLTNSSVKPRLSLP--FIKVAIVKNFITCTTEKIMKFNERLKGALAEIYLTAELLLSELIKAIRVHMGVLYRLSEISATLDLLLSFAQVSKMQNYIRPEFTDTLAIKNCRNPLLDRLSNKEAISNHVYAANLSNFTIVTGANMSGKSMYLRQIALVQIMGQIGCFIPAEYASFRLSDHLFTRIGVDDDIQSNSSTFTIEMREMSYIINTITDNSLVLIDELGRGTSFDEGLGICFAICEHLLQTKAFIFIATHFRELSKLEILYPNVQNVNFEVKNLSESDGDENHLLFTYKCVRGVC--PDFTNAMKLA 2592
            ++EGRG+A GEIG+AS+DLK P+L LSQFSDS  Y + L+KL + +P+EI+ P+T CENG  +KLF+ + +    S++ T+ R+Y+N+  G E I+ LC  +Y +++  E   KYY LA  AA++KYVEFIQNI++AP SL+++F GS + ++ID+ + +NLEL++N +D     SLF  LN+T T GG +              TI  R DC+ EL    ELF+ +++ I  F+ ++HL S+CVQ+PK++TVK+AE+ I  VI LKH +ELI  L++ L+   + LF  Y   L D R+  I+  I  V+H+D  ++KG L MR+QK FA+K    V                    +LD+ARR+Y+E ++ + D ++ L+ ++ LPL+V F+N+RGF+IQ+ L+        SLP   IKV+ VKN +T +T  ++K N+R++ +L EIYL A +++SEL+  IR  +G LY+L+E+ + LD+L+SFA +  + +Y+RPEFTDTLAIK  R+P+LD++ ++  + N++YAA  +NF I+TG NMSGKS YL+QIAL+Q+M QIGC++PAEYASFRL+D +F+RIG DDDI++NSSTF +EM+E++YII   +D SL+++DELGRGTS +EG+GIC+A+CEHLL  KAF F ATHF EL+ ++ LYPNV+N++FE+++   +      LL+  +  + VC  P F N +++ 
Sbjct:  103 IVEGRGLARGEIGMASIDLKRPQLILSQFSDSQTYVKVLTKLQILEPLEIIMPNTACENGNTTKLFKFLGDQFVHSNLATVQRKYFNETKGLEYIKQLCVPEY-NTVEMEVASKYYCLATAAALLKYVEFIQNIVYAPLSLKVVFKGSEQTSMIDVTTAKNLELIQNVRDAKSEHSLFGVLNYTRTAGGNK-------------ETINMRLDCIAELTEKEELFYNIQTVIGRFLDVDHLTSMCVQIPKHETVKTAESKINTVIYLKHTLELIEPLQSALKDTDTPLFKAYFESLKDPRFTAIMEKIQSVIHDDTRYQKGALNMRTQKCFAVKYEQTVEKYECMCLDFRPSVVRCPVGLLDVARRTYTETVDDITDLIKQLAEKYELPLKVGFNNTRGFFIQMQLSKEQDVDTSSLPGELIKVSKVKNNLTFSTGDLIKLNDRIRESLNEIYLMANVVVSELLSDIRDQIGCLYKLAELVSMLDMLVSFAHICTLSDYVRPEFTDTLAIKQGRHPILDKILHETPVPNNMYAAEGTNFLIITGPNMSGKSTYLKQIALLQVMAQIGCYVPAEYASFRLADQIFSRIGSDDDIETNSSTFMLEMKEINYIIQNASDKSLIIVDELGRGTSSEEGVGICYAVCEHLLGIKAFTFFATHFLELTTMDELYPNVENLHFEIQSQVCAKVSSTFLLYI-EGRKFVCNFPRFFNTLRVG 800

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BLAST of mutS protein homolog 4 vs. Ensembl Nematostella
Match: EDO38319 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SD83])

HSP 1 Score: 193.741 bits (491), Expect = 2.931e-51
Identity = 205/763 (26.87%), Postives = 346/763 (45.35%), Query Frame = 1

Query:  541 GVASGE--IGIASVDLKNPELELSQFSDSIGYSRTLSKLYLKDPVEIVFPHTMCENGVRSKLFQIVSEFMHKSSITTIHRRYYNDKNGKEIIQHLCH-----KDYTSSILYESREKYYALAACAAIIKYVEFIQN----ILFAPGSLQIIFSGSVKCAIIDIASVRNLELVENSKDLTENGSLFSAL-NFTTTNGGYRLLRANILQPSFDIPTITSRYDCVEELMNNAELFFTLKSQIKHFVSLNHLLSLCVQLPKNQTVKSAENTITQVIALKHVMELIPTLRATLQSFKSSLFIEYHSLLVDSRYDEILSIINVVVHEDVHFEKGI-LQMRSQKLFAIKDGINVILDIARRSYSEQIEALRDEV----QALSVEHALPLRVAFSNSRGFYIQLPLTNSSVKPRLSLPFIKVAIVKNFITCTTEKIMKFNERLKGALAEIYLTAELLLSELIKAIRVHMGVLYRLSEISATLDLLLSFAQVSKMQN--YIRPEFT-----DTLAIKNCRNPLLDRLSNKEAISNHV-YAANLSNFTIVTGANMSGKSMYLRQIALVQIMGQIGCFIPAEYASFRLSDHLFTRIGVDDDIQSNSSTFTIEMREMSYIINTITDNSLVLIDELGRGTSFDEGLGICFAICEHLL-QTKAFIFIATHFRELSKLEILYPNVQNVNFEVKNLSESDGDENHLLFTYKCVRGVCPDFTNAMKLAKLSNLPKQLLFEAEKIYGRL----GDSNELIIEVKSQFIRNIHKGRPLGKERG 2739
            G  +G+  +G+A  D+ + +L + +F+D+  +S   + +    P E +   T   +G  +K  ++V     +S+I    R+     N K+I+Q L           S+ L E  +  +A AA AA+IKY+E + +      F   S  +  S  +K   +D A+VR L L+ N  D        + L N   T  G RL+   I QP  D   I  R + VE  + + EL  TL+ ++K F   + L        K Q  K+   T+   + +   ++ +      L+ +      ++  LLV+   D ++ ++          E  I L+      + IK   +  L   R    E +E    E+    + LS+E +  +++  +N  G++ ++      V  R +  +  +   K+ +  T   + + N+  +G           L +E++K    +   +  LS++ A +D L+SFA VS      Y+RP  T       + +   R+P L+   N   I+N V  + +   F I+TG NM GKS Y+RQI ++ +M Q+GCF+P   A   ++D +  R+G  D      STF  EM E + I+ T T +SL++IDELGRGTS  +G G+ +AI E++  Q K+F   ATHF EL+ L      V N++        +      L   YK   GVC D +  + +A+L++ P  ++  A++    L    G S EL   V      +  K R L K+ G
Sbjct:   13 GTVTGQRVVGVAYADVASRKLGVCEFADNDQFSNLEALIVQLGPKECLMASTDS-SGDAAKTHEVVK----RSNILVTERKKVEFSN-KDIVQDLNRLLKLTAGGNSATLPE-MDMIHATAALAAVIKYLELLSDESNFSQFKLSSFDL--SQYMK---LDAAAVRALNLLPNPMDGGNKSMCLTGLLNKCKTPQGQRLVAQWIKQPLMDKNKIEERLNIVEAFVEDTELRQTLQDEMKKFPDFSRLAK------KFQRQKA---TLQDCVRVYQSVQRLEPFADVLERYHG----DHRKLLVECFRDPLMELVADFAKFCDLVETTIDLEQVENHEYLIKATFDEGLQECREHMDEILEKFPVELNKAGRDLSLEPSKTIKLESNNQLGYFFRITRKEEKVL-RNNKRYSTIETRKDGVRFTNSALSQLNDEFRGYKDTYNDVQGKLAAEVLKIAGGYSEPMQGLSDVIAQIDALVSFAHVSANAPIPYVRPTITPKGSEGDIILTGSRHPCLEIQDNVAFIANDVTLSRDKQMFLIITGPNMGGKSTYIRQIGVIVLMAQLGCFVPCSTAQISITDCILARVGSGDSQLKGVSTFMSEMLETASILRTATKDSLIIIDELGRGTSTYDGFGLAWAISEYIATQIKSFCLFATHFHELTSLADEVSTVTNLHVTALTTGGT------LTLLYKVKPGVC-DQSFGIHVAELAHFPSDVIEFAKQKAAELEDFQGSSAELGQGVTDSTGESQAKRRRLAKQEG 742

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BLAST of mutS protein homolog 4 vs. Ensembl Nematostella
Match: EDO26509 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7TBU4])

HSP 1 Score: 171.4 bits (433), Expect = 7.175e-48
Identity = 101/259 (39.00%), Postives = 155/259 (59.85%), Query Frame = 1

Query: 1900 ATLDLLLSFAQVSKMQNYIRP---EFTDTLAIKNCRNPLLDRL--SNKEAISNHVY-AANLSNFTIVTGANMSGKSMYLRQIALVQIMGQIGCFIPAEYASFRLSDHLFTRIGVDDDIQSNSSTFTIEMREMSYIINTITDNSLVLIDELGRGTSFDEGLGICFAICE--HLLQTKAFIFIATHFRELSKLEILYPNVQNVNFEVKNLSESDGDENHLLFTYKCVRGVCPDFTNAMKLAKLSNLPKQLLFEAEKIYGRL 2652
            A LD LLSFA+ +   NY+RP   E TD L IKN R+P++++     +E I+N V    N     ++TG NMSGKS  LRQ AL+ ++ Q+G ++PA+ A   + D +FTR+G  D+I    STF +EM E + I+N I++ SLVL+DE+GRGTS  +G+ I +AI E  H   +KA    ATH+ EL+ +   +  ++N N  VK L ++      ++F  K V G   + +  + +AKL+ +P +++  A KI  +L
Sbjct:   13 AQLDCLLSFAKTAIDNNYVRPILDESTD-LEIKNGRHPVIEKQLPIGEEYIANDVVLNRNQQQIIMITGPNMSGKSAILRQTALIVLLAQMGSYVPAQNARIGIVDKIFTRVGASDNISMGESTFMVEMNETASILNNISERSLVLLDEIGRGTSTYDGISIAWAIAEFLHEHPSKAKTLFATHYHELNDMTETFERIKNYNVSVKELKDT------IIFLRKLVAG-GSNHSFGIHVAKLAGMPNRVIHRASKILEQL 263

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BLAST of mutS protein homolog 4 vs. Ensembl Nematostella
Match: EDO38799 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SBW8])

HSP 1 Score: 158.688 bits (400), Expect = 9.914e-40
Identity = 188/747 (25.17%), Postives = 325/747 (43.51%), Query Frame = 1

Query:  520 CLLIEGRGVASG-EIGIASVDLKNPELELSQFSDSIGYSRTLSKLYLKDPVEIVFPHTMCENGVRSKLFQIVSEFMHKSSITTIHRRYYN-----DKNGKEIIQHLCHK-DYT-SSILYESREKYYA--------LAAC-AAIIKYVE--FIQNILFAPGSLQIIFSGSVKCAIIDIASVRNLELVENSKDLTENGSLFSALNFTTTNGGYRLLRANILQPSFDIPTITSR---YDCVEELMNNAELFFTLKSQIKHFVSLNHLLSLC-VQLPKNQTVK--SAENTITQVIALKHVMELIPTLRATLQSFKSSLFIEYHSLLVDSRYDEILSIINVVVHEDVHFEKGILQMRSQKLFAIKDGINVILDIARR--SYSEQIEALRDEVQALSVEHALPLRVAFSNSRGFYIQLPLTNSSVKPRLSLPFIKVAIVKN-------FITCTTEKIMKFNERLKGALAEIYLTAELLLSELIKAIRVHMGVLYRLSEISATLDLLLSFAQVSKMQNYIRPEF-----TDTLAIKNCRNPLLDRLSNKEA---ISNHVYAANLSNFTIVTGANMSGKSMYLRQIALVQIMGQIGCFIPAEYASFRLSDHLFTRIGVDDDIQSNSSTFTIEMREMSYIINTITDNSLVLIDELGRGTSFDEGLGICFAICEHLL-QTKAFIFIATHFRELSKLEILYPNVQNVNFEVKNLSESDG-------DENHLLFTYKCVRGVCPDFTNAMKLAKLSNLP 2610
            C+  E  G  +G   GI +V     E+    F DS   S   ++L    P E++   T+ E   R++ F  V    +KS+      R  +       +  +I+Q  C+  D T  S    S+E            +  C  ++ KY++   +  +L   G+ +  FS   K   ++  +++NLE+++ S+  +  GSL   L+ T+T  G RLL+  I QP  +   I  R     C+  L ++  L  ++   + H   L     LC +   K  TV+  S    ++++       EL         S  S  F E   LL  S  ++ L+ I+         EK        KLF        +L   +     + +++  R E++  +++H     V +    G    + + N+ + P +   +IK++  K        F+    + I ++ E+L  A  E +L       E +          +R  ++ A LD ++S A V++   Y+ P         ++ I   R+P++D L  + A    +N           I+TG NM GKS Y++Q+AL+ +M Q+G F+PA        D ++TR+G  D+I    STF +E++E S I+   T  SLV++DELGRGTS  +G+ I +A   H + QT +     TH+  L++LE ++P     N      S+ D        D   + F Y+ VRGV    +  + +A+L+ +P
Sbjct:  149 CVHEEDSGAKTGITYGIVAVQPSTGEIIYDYFPDSPSCSELETRLEHLSPSELLIHDTLSE---RTRSFLDVFSSYYKSADPIRTERIPDPLPSSQSDANQILQEFCNSTDETFGSSSPNSQETLLQTLLTLPLPVQKCFISLQKYLKDFKLDKVLKLAGNFEK-FSTIAKFMKLNGCALQNLEILK-SQCGSRKGSLLGILDHTSTPFGKRLLKRWITQPLLEKREIEERLKAVSCLSALSSDQPLLKSIHRLLSHIPDLEK--GLCAIYYKKCSTVEFLSIAKALSKLHDELKSTELNSAKELAGSSILSRTFTEVPDLL--SGVEDFLNQID---------EKAAKCGDKTKLFTDPSKFPPVLTCIQEIDGLTAELKEHRSEIRR-TIQHP---SVDYCTVSGNEFLIEVRNAKL-PSVPADWIKISATKQICRFRTPFVEEKFKSICQWREKLAQACQEAWL-------EFLDIFSTSYTRFHRAVKLVANLDCIMSLATVARQPGYVCPVIKKETEASSVLITQGRHPVIDVLLQEHAQYVPNNTELNTEGPRCMIITGPNMGGKSSYIKQVALIVLMAQMGSFVPAHSVELTPLDAIYTRMGASDNIYKGRSTFMVELQETSEILAQATRRSLVILDELGRGTSTHDGVAIAYATLRHFIDQTHSLTLFVTHYPSLAELERIFPGHVTNNHMAFMTSDGDTELASVAMDTPAVTFLYELVRGVAAR-SYGLNVARLAGIP 864

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BLAST of mutS protein homolog 4 vs. Ensembl Nematostella
Match: EDO48759 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RIQ7])

HSP 1 Score: 152.525 bits (384), Expect = 9.626e-38
Identity = 151/548 (27.55%), Postives = 257/548 (46.90%), Query Frame = 1

Query: 1042 ENGSLFSALNFTTTNGGYRLLRANILQPSFDIPTITSRYDCVEELMN--NAELFFTLKSQIKHFVSLNHLLSLCVQLPKNQTV-------KSAENTITQVIALKHVMELIPTLRATLQSFKSSLFIEYH-SLLVDSRYDEILSIINVVVHEDVHFEKGILQMRSQKLFAIKDGINVILDIARRSYSE----QIEALRDEVQALSVEHALPLRVAFSNSRGFYIQLPLTNSSVKPRLSLPFIKVAIVKNFITCTTEKIMKFNERL--KGALAEIYLTAELLLSELIKAIRVHMGVLYRLSEISATLDLLLSFAQVSKMQNYIRPEFTDT--LAIKNCRNPLLDRLSNKEAISNHVYAANLSNFTIVTGANMSGKSMYLRQIALVQIMGQIGCFIPAEYASFRLSDHLFTRIGVDDDIQSNSSTFTIEMREMSYIINTITDNSLVLIDELGRGTSFDEGLGICFAICEHLLQTKA---FIFIATHFRELSKLEILYPNVQNVNFEVKNLSESDGDENHLLFTYKCVRGVCPDFTNAMKLAKLSNLPKQLL 2622
            E  SLF  LN T +  G RLLR   L+P+ DI  +T R   +       N +L  +L+  +K+  +++  L +  +  K ++V       K+A+ +IT   AL   +     +    ++  S + I    ++LV      I S+IN ++  D   E        Q  F +K G++  LD  +R+Y+       +  R E+  L+    +   V +    G+ + +P T             K+   K+F     + +   N  +  K A    + TA  ++  L   I     VL  + E +A LD L+S A  ++  NY+ PE T    L I    +PL +   ++   ++     +     I+TG N SGKS+YL+Q+ L+  +  IG F+PAE A   ++D LFTRI   + +    STF I++ +++  I + TD SLVLIDE G+GT+  +GL +  A   H L + +      ++THF  L + ++L P++  + F+   + + DG E  L+F Y  V G     + A  +A L+ +P+ L+
Sbjct:  262 EGLSLFGVLNRTRSALGSRLLRMWFLRPTRDILVLTERQKAITFFTTPRNIDLIASLQDCLKNVKNVSVRLYITKRELKVKSVPRILVRMKTAQASITDWQALYKTVYNAMYIADLCRTIPSEIAIAKKITVLVTQDLHNIASLINTIIDFDDSTE--------QNRFVVKPGVDPALDERKRTYNGLPDFMTKVARKELNKLN-PSIVECNVIYLPQLGYLLAVPRTT------------KMKEEKDFEMDGLDFVFLSNNMVYYKSASTRDHETA--IMHRLQSTILERTKVLLDVMECTAELDCLISLAVSARENNYVCPEITSKSILHITGGMHPLQELCVSQFVPNDTAINEDSGRVVILTGPNASGKSVYLKQVGLIVFLAHIGSFVPAESAIIGVTDRLFTRIHTRETVSVGLSTFMIDLNQVASAIQSATDKSLVLIDEFGKGTATVDGLSLLCATLRHWLASSSKCPKTLVSTHFHSLIRQKLL-PDIPILRFQTTEVIQ-DGKE--LVFLYHLVDGHAKT-SYASHIAALAGMPEHLV 781

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BLAST of mutS protein homolog 4 vs. Ensembl Medaka
Match: msh4 (mutS homolog 4 [Source:NCBI gene;Acc:101160275])

HSP 1 Score: 649.047 bits (1673), Expect = 0.000e+0
Identity = 344/735 (46.80%), Postives = 497/735 (67.62%), Query Frame = 1

Query:  526 LIEGRGVASGEIGIASVDLKNPELELSQFSDSIGYSRTLSKLYLKDPVEIVFPHTMCENGVRSKLFQIVSEFMHKSSITTIHRRYYNDKNGKEIIQHLCHKDYTSSILYESREKYYALAACAAIIKYVEFIQNILFAPGSLQIIFSGSVKCAIIDIASVRNLELVENSKDLTENGSLFSALNFTTTNGGYRLLRANILQPSFDIPTITSRYDCVEELMNNAELFFTLKSQIKHFVSLNHLLSLCVQLPKNQTVKSAENTITQVIALKHVMELIPTLRATLQSFKSSLFIEYHSLLVDSRYDEILSIINVVVHEDVHFEKGILQMRSQKLFAIKDGINVILDIARRSYSEQIEALRDEVQALSVEHALPLRVAFSNSRGFYIQLPLTNSSVKPRLSLP--FIKVAIVKNFITCTTEKIMKFNERLKGALAEIYLTAELLLSELIKAIRVHMGVLYRLSEISATLDLLLSFAQVSKMQNYIRPEFTDTLAIKNCRNPLLDRLSNKEAISNHVYAANLSNFTIVTGANMSGKSMYLRQIALVQIMGQIGCFIPAEYASFRLSDHLFTRIGVDDDIQSNSSTFTIEMREMSYIINTITDNSLVLIDELGRGTSFDEGLGICFAICEHLLQTKAFIFIATHFRELSKLEILYPNVQNVNFEVKNLSESDGDENHLLFTYKCVRGVCPDFTNAMKLAKLSNLPKQLLFEAEKIYGRLGDSNELI----IEVKSQFIRNIHK 2712
            ++EGRG+A GEIG+AS++LK PEL LSQF+D+  Y++ ++K+++  PVEI+ P T CE G  +KLF++++E       T I R+Y+N+K G E IQ LC  +Y  ++L E + KYY LAA AA++KY+EF+QN ++A  SL++ F GS + A+ID AS  NLELV N++D     +L   LN T T GG R LR+NIL+P  ++ TI  R D V+EL+ + ELFF LK+ I HF+ ++ LLS+ VQ+PK +TV++AE  IT VI LKH ++L+P LR   ++  + L   Y S L D+R+D IL  I  V++ D  + KG L MR+QK +A++  IN  LDIARR+Y+E ++ +   V  +  ++ LP+R +FS SRGF+IQL L + SV PR SLP   IKV   KN    TT  +MK N R   AL EI+  + +++ +L+  I  H+  LY+LS+  + LD+LLS A    + +Y+RPEFTDTLAIK  R+P+L+R++ ++  SN+ Y +  SNF I+TG NMSGKS YL+Q+AL QIM QIG F+PAEYASFRL+  +FTRIGVDDD ++NSS+F +EM+E+SYII+  +D SL++IDELGRGTS +EG+GIC ++CE LL  KAF   ATHF EL +LE LYPNV+N + EV++    D    H+++TY   RG   +    ++ A+++ LP  ++ EA  I  ++  S +L+    I+ KS   R +++
Sbjct:  123 VVEGRGLARGEIGMASLNLKCPELVLSQFADTGTYAKVITKIHILVPVEILMPDTACEKGKGTKLFKLITENFPGVPFTAIQRKYFNEKKGLEYIQQLCAPEY-GTVLMEVQAKYYCLAAAAALLKYLEFLQNSVYAAKSLKVTFKGSEQTAMIDSASAYNLELVVNNRDHRSEHTLLGVLNHTKTPGGARRLRSNILEPLVNVDTINMRLDAVQELLQDEELFFGLKNAICHFLDVDRLLSVLVQIPKQETVQAAEAKITHVIQLKHTLDLVPQLRTVFKNCNTPLLKAYSSTLEDNRFDMILEQIKTVINPDTMYLKGSLNMRTQKCYAVRPNINEFLDIARRAYTEIVDDIAVLVNQMGEKYGLPMRTSFSTSRGFFIQLKL-DGSVLPRGSLPPECIKVTKHKNNYCFTTADLMKMNGRCDEALREIFHMSYVVICQLLSTIHGHIHCLYKLSDAVSMLDMLLSLANACTISDYVRPEFTDTLAIKQGRHPILERMARQQPTSNNAYISEGSNFVIITGPNMSGKSTYLKQVALCQIMAQIGSFVPAEYASFRLAGQIFTRIGVDDDFETNSSSFMLEMKEISYIIHNASDRSLIIIDELGRGTSAEEGVGICHSVCEFLLGLKAFTLFATHFLELCQLESLYPNVENQHMEVQHTRSGDTGVEHVVYTYLLKRGCSEERLYGLRAAEMTALPPNIIQEARTIASKV--SQQLMARHHIDPKSHRQRALYR 853

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BLAST of mutS protein homolog 4 vs. Ensembl Medaka
Match: msh4 (mutS homolog 4 [Source:NCBI gene;Acc:101160275])

HSP 1 Score: 632.484 bits (1630), Expect = 0.000e+0
Identity = 337/731 (46.10%), Postives = 489/731 (66.89%), Query Frame = 1

Query:  526 LIEGRGVASGEIGIASVDLKNPELELSQFSDSIGYSRTLSKLYLKDPVEIVFPHTMCENGVRSKLFQIVSEFMHKSSITTIHRRYYNDKNGKEIIQHLCHKDYTSSILYESREKYYALAACAAIIKYVEFIQNILFAPGSLQIIFSGSVKCAIIDIASVRNLELVENSKDLTENGSLFSALNFTTTNGGYRLLRANILQPSFDIPTITSRYDCVEELMNNAELFFTLKSQIKHFVSLNHLLSLCVQLPKNQTVKSAENTITQVIALKHVMELIPTLRATLQSFKSSLFIEYHSLLVDSRYDEILSIINVVVHEDVHFEKGILQMRSQKLFAIKDGINVILDIARRSYSEQIEALRDEVQALSVEHALPLRVAFSNSRGFYIQLPLTNSSVKPRLSLP--FIKVAIVKNFITCTTEKIMKFNERLKGALAEIYLTAELLLSELIKAIRVHMGVLYRLSEISATLDLLLSFAQVSKMQNYIRPEFTDTLAIKNCRNPLLDRLSNKEAISNHVYAANLSNFTIVTGANMSGKSMYLRQIALVQIMGQIGCFIPAEYASFRLSDHLFTRIGVDDDIQSNSSTFTIEMREMSYIINTITDNSLVLIDELGRGTSFDEGLGICFAICEHLLQTKAFIFIATHFRELSKLEILYPNVQNVNFEVKNLSESDGDENHLLFTYKCVRGVCPDFTNAMKLAKLSNLPKQLLFEAEKIYGRLGDSNELIIEVKSQFIRNIHK 2712
            ++EGRG+A GEIG+AS++LK PEL LSQF+D+  Y++ ++K+++  PVEI+ P T CE G  +KLF++++E       T I R+Y+N+K G E IQ LC  +Y  ++L E + KYY LAA AA++KY+EF+QN ++A  SL++ F GS + A+ID AS  NLELV N++D     +L   LN T T GG R LR+NIL+P  ++ TI  R D V+EL+ + ELFF LK+ I HF+ ++ LLS+ VQ+PK +TV++AE  IT VI LKH ++L+P LR   ++  + L  +             LS I  V++ D  + KG L MR+QK +A++  IN  LDIARR+Y+E ++ +   V  +  ++ LP+R +FS SRGF+IQL L + SV PR SLP   IKV   KN    TT  +MK N R   AL EI+  + +++ +L+  I  H+  LY+LS+  + LD+LLS A    + +Y+RPEFTDTLAIK  R+P+L+R++ ++  SN+ Y +  SNF I+TG NMSGKS YL+Q+AL QIM QIG F+PAEYASFRL+  +FTRIGVDDD ++NSS+F +EM+E+SYII+  +D SL++IDELGRGTS +EG+GIC ++CE LL  KAF   ATHF EL +LE LYPNV+N + EV++    D    H+++TY   RG   +    ++ A+++ LP  ++ EA  I  ++  S +L++  KS   R +++
Sbjct:   77 VVEGRGLARGEIGMASLNLKCPELVLSQFADTGTYAKVITKIHILVPVEILMPDTACEKGKGTKLFKLITENFPGVPFTAIQRKYFNEKKGLEYIQQLCAPEY-GTVLMEVQAKYYCLAAAAALLKYLEFLQNSVYAAKSLKVTFKGSEQTAMIDSASAYNLELVVNNRDHRSEHTLLGVLNHTKTPGGARRLRSNILEPLVNVDTINMRLDAVQELLQDEELFFGLKNAICHFLDVDRLLSVLVQIPKQETVQAAEAKITHVIQLKHTLDLVPQLRTVFKNCNTPLLKQ-------------LSSIKTVINPDTMYLKGSLNMRTQKCYAVRPNINEFLDIARRAYTEIVDDIAVLVNQMGEKYGLPMRTSFSTSRGFFIQLKL-DGSVLPRGSLPPECIKVTKHKNNYCFTTADLMKMNGRCDEALREIFHMSYVVICQLLSTIHGHIHCLYKLSDAVSMLDMLLSLANACTISDYVRPEFTDTLAIKQGRHPILERMARQQPTSNNAYISEGSNFVIITGPNMSGKSTYLKQVALCQIMAQIGSFVPAEYASFRLAGQIFTRIGVDDDFETNSSSFMLEMKEISYIIHNASDRSLIIIDELGRGTSAEEGVGICHSVCEFLLGLKAFTLFATHFLELCQLESLYPNVENQHMEVQHTRSGDTGVEHVVYTYLLKRGCSEERLYGLRAAEMTALPPNIIQEARTIASKV--SQQLMVYPKSHRQRALYR 790

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BLAST of mutS protein homolog 4 vs. Ensembl Medaka
Match: msh3 (mutS homolog 3 [Source:NCBI gene;Acc:101156254])

HSP 1 Score: 200.29 bits (508), Expect = 2.792e-52
Identity = 191/732 (26.09%), Postives = 337/732 (46.04%), Query Frame = 1

Query:  559 IGIASVDLKNPELELSQFSDSIGYSRTLSKLYLKDPVEIVFPHTMCENGVRSKLFQIVSEFMHKSSITTIHRR------YYNDKNGKEIIQHLCHKDYTSSILYESREKYYALAAC--AAIIKYV-EF-IQNILFAPGSLQIIFSGSVKCAIIDIASVRNLELVENSKDLTENGSLFSALNFTTTNGGYRLLRANILQPSFDIPTITSRYDCVEELM-NNAELFFTLKSQIKHFVSLNHLLSLCVQLPKNQTVKSAENTITQVIALK-HVMELIPTLRATLQS-FKSSLFIEYHSLLVDSRYDEILSIINVVVHEDVHFEKGILQMRSQKLFAIKDGINVILDIARRSYSEQIEALRDEVQALSVEHALPLRVAFS---------NSRGFYIQLPLTNSSVKPRLSLPFIKVAIVKNFITCTTEKIMKFNERLKGALAEIYLTAELLLSELIKAIRVHMGVLYRLSEISATLDLLLSFAQVSKMQNYIRPEFTD---TLAIKNCRNPLLDRLSNKEA--ISNHV-YAANLSNFTIVTGANMSGKSMYLRQIALVQIMGQIGCFIPAEYASFRLSDHLFTRIGVDDDIQSNSSTFTIEMREMSYIINTITDNSLVLIDELGRGTSFDEGLGICFAICEHLLQ-TKAFIFIATHFRELSKLEILYPNVQNVNFEVKNL--------SESDGD--ENHLLFTYKCVRGVCPDFTNAMKLAKLSNLPKQLLFEAEK 2637
            +G+ +V     ++ L  F D    S   S++   +PVEI+ P  + E   R  L  + +          + RR      Y +  N   + Q  C      S        + +   C    +I+Y+ EF ++ +L +  S Q + S   +  I++ A++RNLE++ N  D    GSLF  L+ + T  G RL+R  + QP  D+  I+ R D V+E+M +++ +  ++KS +     L     +C    K  + +      + +  L   +   IP +R+  +S    S+ ++   LL  +     L+++N         EK        +LF+   G  V+     +  ++QI  +  E+Q    EH   +R+            + + F I++  + SS  P     ++K++  K      +  +++  ++L+    ++ L  +   ++ +     H   + R     AT+D L S A+V++   Y RP+  +    + I++ R+P +D L  ++   + NH     +     I+TG NM GKS Y+RQ+AL+ IM QIG F+PA  A   L D ++TR+G  D+I    STF  E+ E S II+  T+ SLV++DELGRGTS  +G+ I +A  E+ ++  K+F    TH+  L +LE +YP+    NF +  L           DGD     + F Y    G     +  + +AKL+++P  +L  A +
Sbjct:  351 VGLVAVQPSTGDVFLDCFPDGSSRSELESRILKINPVEILVPSDLSEETCR-LLLSVTNGSFQADDRARVERRDSAQFEYTSAIN--TVTQFYCRSQQEDSRSLWRVASFESPVICCLGPLIQYLQEFNLERVLRSESSFQRL-SCESEAMILNAATLRNLEILNNQTDRGVRGSLFWVLDHSRTPFGRRLMRKWVSQPLTDLQRISERQDAVQEIMESDSPILDSVKSLLPRLPDLER--GICSIYHKKSSTQEFYLISSHLSRLGLQLQSWIPAIRSQTRSVLLRSVLLDTPDLLAPAHT--FLNVLN---------EKAARSGNKTELFSDLSGFPVL-----QERTKQIHFVLSEIQ----EHLKDIRMVLKAPTLNYITVSGQEFLIEVKNSLSSTVPS---DWVKISSTKAVGRYHSPLLVERYKKLQQLREQLLLDCQREWTDFLDQFGEHYHTMKRAISHLATIDCLFSLAEVAQQGGYCRPKVCEDQPQIMIRDGRHPAIDLLMGEQNQFVPNHTDLQGDGKRTMIITGPNMGGKSSYIRQVALICIMAQIGSFVPASEACLGLLDGIYTRMGASDNIYKGRSTFMEELTEASEIISRATERSLVILDELGRGTSTHDGIAIAYATLEYFIRHVKSFTLFVTHYPPLCELERMYPD-HVSNFHMAFLLNETHISSDTKDGDVQPEFITFLYNLTEGAAGQ-SYGLNVAKLADVPDPILCTAAR 1051

[Close]

BLAST of mutS protein homolog 4 vs. Ensembl Medaka
Match: msh2 (mutS homolog 2 [Source:NCBI gene;Acc:101167993])

HSP 1 Score: 197.208 bits (500), Expect = 1.830e-51
Identity = 195/721 (27.05%), Postives = 327/721 (45.35%), Query Frame = 1

Query:  559 IGIASVDLKNPELELSQFSDSIGYSRTLSKLYLKDPVEIVFPHTMCENGVRSKLFQIVSEFMHKSSITTIHRRYYNDKNGKEIIQHLCH-------KDYTSSILYESREKYYALAACAAIIKYVEFIQNIL-FAPGSLQIIFSGSVKCAIIDIASVRNLELVENS-KDLTENGSLFSALNFTTTNGGYRLLRANILQPSFDIPTITSRYDCVEELMNNAELFFTLKSQIKHFVSLNHLLSLCVQLPKNQTVKSAENTITQVIALKHVMELIPTLRATLQSFKSS----LFIEYHSLLVD-----SRYDEILSI---INVVVHED----VHFEKGILQMRSQKLFAIKDGINVILDIARRSYSEQIEALRDEVQALSVEHALPLRVAFSNSRGFYIQLPLTNSSVKPRLSLPFIKVAIVKNFITCTTEKIMKFNERLKGALAEIYLTAELLLSELIKAIRVHMGVLYRLSEISATLDLL--LSFAQVSKMQNYIRPEFTDT----LAIKNCRNPLLDRLSNKEAISNHV-YAANLSNFTIVTGANMSGKSMYLRQIALVQIMGQIGCFIPAEYASFRLSDHLFTRIGVDDDIQSNSSTFTIEMREMSYIINTITDNSLVLIDELGRGTSFDEGLGICFAICEHLL-QTKAFIFIATHFRELSKLEILYPNVQNVNFEVKNLSESDGDENHLLFTYKCVRGVCPDFTNAMKLAKLSNLPKQLL 2622
            +G+  VD    ++ + +F D+  +S   S L    P E +        G  S     + E + +  +  +  R   D + K+I Q L         +   SS L E  +K  A++  AA++++++ + +   F   SL  +  G  +   +D A+V  L L + S  D++   SL   LN   T  G RL+   I QP  D   I  R D VE  + ++EL  T +  + H     H      +L K     SA  T+     +   +  IP L A  + +  S    L   + S L D     ++Y E++     +N + H +      F+  + ++R +K+  +++ +  +L+ A R               L +E    +++  +   GFY+++         R +  F  + + KN +  T  K+   NE       E       ++ E+I     ++  L  LS++ A LD +  L+ A VS    Y+RP   D     L +   R+P ++  ++   I N V +     +F I+TG NM GKS Y+RQ+ ++ +M QIGCF+P E A   ++D +  R+G  D      STF  EM E + I+ + T+NSL++IDELGRGTS  +G G+ +AI EH+  +   F   ATHF EL+ L    P+V N++  V  L+      N L   Y+   GVC D +  + +A+L+  P  +L
Sbjct:  160 VGVGYVDAAQRKMGVCEFPDNEIFSNLESLLVQISPKECLLAQ-----GDSSTDGNKLREVVQRGGML-VSDRKRADFSSKDITQDLNRLLRVKKGEAMASSTLSE-LDKQVAMSCLAAVVRFLDLLSDESNFNSFSLASLDLG--QYMRLDNAAVGALNLFQGSPDDISGAHSLAGLLNKCRTPQGQRLVNQWIKQPLMDKTKIEERLDLVESFVCDSELRQTCQGDLLHRFPDLH------RLAKKFHRHSA--TLQDCYRVYQAVSQIPGLIAAFEKYSGSYQVLLQAVFTSPLTDLQTDFTKYQEMVETTLDMNQIDHHEFLVKASFDPVLTELR-EKMDDLEESMQAVLNSAARE--------------LGLEAGKTVKLESNAMLGFYLRVTCKEEK-GLRNNKKFTTLDVQKNGVRFTNSKLSSLNEEYTRNKEEYEEAQNAIVKEIINIASGYVDPLQTLSDVIAQLDAVVSLALASVSAPVPYVRPRILDEGCRRLELVQARHPCMETDADTAFIPNDVSFVQGERSFYIITGPNMGGKSTYIRQVGVIALMAQIGCFVPCEKAELSVTDSILARVGAGDSQVKGVSTFMSEMLETAAILRSATENSLIIIDELGRGTSTYDGFGLAWAISEHIASKISCFCLFATHFHELTALASQQPSVHNLH--VTALTT----HNTLTMLYRVKAGVC-DQSFGIHVAELACFPPAVL 840

[Close]

BLAST of mutS protein homolog 4 vs. Ensembl Medaka
Match: msh3 (mutS homolog 3 [Source:NCBI gene;Acc:101156254])

HSP 1 Score: 178.718 bits (452), Expect = 2.298e-45
Identity = 183/723 (25.31%), Postives = 319/723 (44.12%), Query Frame = 1

Query:  559 IGIASVDLKNPELELSQFSDSIGYSRTLSKLYLKDPVEIVFPHTMCENGVRSKLFQIVSEFMHKSSITTIHRR------YYNDKNGKEIIQHLCHKDYTSSILYESREKYYALAAC--AAIIKYV-EF-IQNILFAPGSLQIIFSGSVKCAIIDIASVRNLELVENSKDLTENGSLFSALNFTTTNGGYRLLRANILQPSFDIPTITSRYDCVEELM-NNAELFFTLKSQIKHFVSLNHLLSLCVQLPKNQTVKSAENTITQVIALK-HVMELIPTLRATLQS-FKSSLFIEYHSLLVDSRYDEILSIINVVVHEDVHFEKGILQMRSQKLFAIKDGINVILDIARRSYSEQIEALRDEVQALSVEHALPLRVAFSNSRGFYIQLPLTNSSVKPRLSLPFIKVAIVKNFITCTTEKIMKFNERLKGALAEIYLTAELLLSELIKAIRVHMGVLYRLSEISATLDLLLSFAQVSKMQNYIRPEFTD---TLAIKNCRNPLLDRLSNKEA--ISNHV-YAANLSNFTIVTGANMSGKSMYLRQIALVQIMGQIGCFIPAEYASFRLSDHLFTRIGVDDDIQSNSSTFTIEMREMSYIINTITDNSLVLIDELGRGTSFDEGLGICFAICEHLLQ-TKAFIFIATHFRELSKLEILYPNVQNVNFEVKNL--------SESDGD--ENHLLFTYKCVRGVCPDFTNAMKLAKLSNLPKQLLFEAEK 2637
            +G+ +V     ++ L  F D    S   S++   +PVEI+ P  + E   R  L  + +          + RR      Y +  N   + Q  C      S        + +   C    +I+Y+ EF ++ +L +  S Q + S   +  I++ A++RNLE++ N  D    GSLF  L+ + T  G RL+R  + QP  D+  I+ R D V+E+M +++ +  ++KS +     L     +C    K  + +      + +  L   +   IP +R+  +S    S+ ++   LL  +     L+++N         EK        +LF+   G  V+     +  ++QI  +  E+Q    EH   +R+                              A   N+IT + ++ +     +K +L+    +  + +S      R H  +L    +    L   L      +  +++ P+  +    + I++ R+P +D L  ++   + NH     +     I+TG NM GKS Y+RQ+AL+ IM QIG F+PA  A   L D ++TR+G  D+I    STF  E+ E S II+  T+ SLV++DELGRGTS  +G+ I +A  E+ ++  K+F    TH+  L +LE +YP+    NF +  L           DGD     + F Y    G     +  + +AKL+++P  +L  A +
Sbjct:  351 VGLVAVQPSTGDVFLDCFPDGSSRSELESRILKINPVEILVPSDLSEETCR-LLLSVTNGSFQADDRARVERRDSAQFEYTSAIN--TVTQFYCRSQQEDSRSLWRVASFESPVICCLGPLIQYLQEFNLERVLRSESSFQRL-SCESEAMILNAATLRNLEILNNQTDRGVRGSLFWVLDHSRTPFGRRLMRKWVSQPLTDLQRISERQDAVQEIMESDSPILDSVKSLLPRLPDLER--GICSIYHKKSSTQEFYLISSHLSRLGLQLQSWIPAIRSQTRSVLLRSVLLDTPDLLAPAHT--FLNVLN---------EKAARSGNKTELFSDLSGFPVL-----QERTKQIHFVLSEIQ----EHLKDIRMVLK---------------------------APTLNYITVSGQEFLI---EVKNSLSSTVPSDWVKISSTKAVGRYHSPLLVERYKKLQQLREQLLLDCQREWTDFLEPKVCEDQPQIMIRDGRHPAIDLLMGEQNQFVPNHTDLQGDGKRTMIITGPNMGGKSSYIRQVALICIMAQIGSFVPASEACLGLLDGIYTRMGASDNIYKGRSTFMEELTEASEIISRATERSLVILDELGRGTSTHDGIAIAYATLEYFIRHVKSFTLFVTHYPPLCELERMYPD-HVSNFHMAFLLNETHISSDTKDGDVQPEFITFLYNLTEGAAGQ-SYGLNVAKLADVPDPILCTAAR 1015

[Close]

BLAST of mutS protein homolog 4 vs. Planmine SMEST
Match: SMESG000019326.1 (SMESG000019326.1)

HSP 1 Score: 1038.1 bits (2683), Expect = 0.000e+0
Identity = 547/558 (98.03%), Postives = 549/558 (98.39%), Query Frame = 1

Query:  124 SFSSDNLVTNNKNDFIFKTPKSRGMEPSCSYQDTDTMSLKTCPNLNHKLKKTIAFSTSILDKKKFRSEVTPYKRTINLPLKYLSTGSKSDLSRIVSNKLVRXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXCLLI---EGRGVASGEIGIASVDLKNPELELSQFSDSIGYSRTLSKLYLKDPVEIVFPHTMCENGVRSKLFQIVSEFMHKSSITTIHRRYYNDKNGKEIIQHLCHKDYTSSILYESREKYYALAACAAIIKYVEFIQNILFAPGSLQIIFSGSVKCAIIDIASVRNLELVENSKDLTENGSLFSALNFTTTNGGYRLLRANILQPSFDIPTITSRYDCVEELMNNAELFFTLKSQIKHFVSLNHLLSLCVQLPKNQTVKSAENTITQVIALKHVMELIPTLRATLQSFKSSLFIEYHSLLVDSRYDEILSIINVVVHEDVHFEKGILQMRSQKLFAIKDGINVILDIARRSYSEQIEALRDEVQALSVEHALPLRVAFSNSRGFYIQLPLTNSSVKPRLSLPFIKVAIVKNFITCTTEKIMKFNER 1788
            +F SDNLVTNNKNDFIFKTPKSRGMEPSCSYQDTDTMSLKTCPNLNHKLKKTIAFSTSILDKKKFRSEVTPYKRTINLPLKYLSTGSKSDLSRIVSNKLVRKSKLPTKTSTTLLSTGPSTSTTTNTKRTSDSCLLI   EGRGVASGEIGIASVDLKNPELELSQFSDSIGYSRTLSKLYLKDPVEIVFPHTMCENGVRSKLFQIVSEFMHKSSITTIHRRYYNDKNGKEIIQHLCHKDYTSSILYESREKYYALAACAAIIKYVEFIQNILFAPGSLQIIFSGSVKCAIIDIASVRNLELVENSKDLTENGSLFSALNFTTTNGGYRLLRANILQPSFDIPTITSRYDCVEELMNNAELFFTLKSQIKHFVSLNHLLSLCVQLPKNQTVKSAENTITQVIALKHVMELIPTLRATLQSFKSSLFIEYHSLLVDSRYDEILSIINVVVHEDVHFEKGILQMRSQKLFAIKDGINVILDIARRSYSEQIEALRDEVQALSVEHALPLRVAFSNSRGFYIQLPLTN+SVKPRLSLPFIKVAIVKNFITCTTEKI     R
Sbjct:   16 AFQSDNLVTNNKNDFIFKTPKSRGMEPSCSYQDTDTMSLKTCPNLNHKLKKTIAFSTSILDKKKFRSEVTPYKRTINLPLKYLSTGSKSDLSRIVSNKLVRKSKLPTKTSTTLLSTGPSTSTTTNTKRTSDSCLLIAIVEGRGVASGEIGIASVDLKNPELELSQFSDSIGYSRTLSKLYLKDPVEIVFPHTMCENGVRSKLFQIVSEFMHKSSITTIHRRYYNDKNGKEIIQHLCHKDYTSSILYESREKYYALAACAAIIKYVEFIQNILFAPGSLQIIFSGSVKCAIIDIASVRNLELVENSKDLTENGSLFSALNFTTTNGGYRLLRANILQPSFDIPTITSRYDCVEELMNNAELFFTLKSQIKHFVSLNHLLSLCVQLPKNQTVKSAENTITQVIALKHVMELIPTLRATLQSFKSSLFIEYHSLLVDSRYDEILSIINVVVHEDVHFEKGILQMRSQKLFAIKDGINVILDIARRSYSEQIEALRDEVQALSVEHALPLRVAFSNSRGFYIQLPLTNNSVKPRLSLPFIKVAIVKNFITCTTEKIKGLKVR 573

[Close]

BLAST of mutS protein homolog 4 vs. Planmine SMEST
Match: SMESG000019325.1 (SMESG000019325.1)

HSP 1 Score: 612.838 bits (1579), Expect = 0.000e+0
Identity = 302/334 (90.42%), Postives = 302/334 (90.42%), Query Frame = 1

Query: 1942 MQNYIRPEFTDTLAIKNCRNPLLDRLSNKEAISNHVYAANLSNFTIVTGANMSGKSMYLRQIALVQIMGQIGCFIPAEYASFRLSDHLFTRIGVDDDIQSNSSTFTIEMREMSYIINTITDNSLVLIDELGRGTSFDEGLGICFAICEHLLQTKAFIFIATHFRELSKLEILYPNVQNVNFEVKNLSESDGDENHLLFTYKCVRGVCPDFTNAMKLAKLSNLPKQLLFEAEKIYGRLGDSNELIIEVKSQFIRNIHKGRPLGKERGVFTKGGMMGQWENEKNTNSIASDYEICKLSAKIEYLAKNVTVDTPEVNFCLKSLQNQCRVTFEKLNKQ 2943
            MQNYIRPEFTDTLAIKNCRNPLLDRLSNKE ISNHVYAANLSNFTIVTGANMSGKSMYLRQIALVQIMGQIGCFIPAEYASFRLSDHLFTRIGVDDDIQSNSSTFTIEMREMSYIINTITDNSLVLIDELGRGTSFDEGLGICFAICEHLLQTKAFIFIATHFRELSKLEILYPNVQNVNFEVKNLSESDGDENHLLFTYKCVRGVCPDFTNAMKLAKLSNLPKQLLFEAEKIYGRLGDSNELIIE                               ENEKNTNSIASDYEICKLSAKIEYLAKNVTVDTPEVNFCLKSLQNQCRVTFEKLNKQ
Sbjct:    1 MQNYIRPEFTDTLAIKNCRNPLLDRLSNKETISNHVYAANLSNFTIVTGANMSGKSMYLRQIALVQIMGQIGCFIPAEYASFRLSDHLFTRIGVDDDIQSNSSTFTIEMREMSYIINTITDNSLVLIDELGRGTSFDEGLGICFAICEHLLQTKAFIFIATHFRELSKLEILYPNVQNVNFEVKNLSESDGDENHLLFTYKCVRGVCPDFTNAMKLAKLSNLPKQLLFEAEKIYGRLGDSNELIIE-------------------------------ENEKNTNSIASDYEICKLSAKIEYLAKNVTVDTPEVNFCLKSLQNQCRVTFEKLNKQ 303

[Close]

BLAST of mutS protein homolog 4 vs. Planmine SMEST
Match: SMESG000016751.1 (SMESG000016751.1)

HSP 1 Score: 200.29 bits (508), Expect = 8.609e-53
Identity = 160/548 (29.20%), Postives = 264/548 (48.18%), Query Frame = 1

Query: 1009 LELVENSKDLTENGSLFSALNFTTTNGGYRLLRANILQPSFDIPTITSRYDCVEELMNNAELFFTLKSQIKHFVSLNHLLSLCVQLPKNQTVKSAENTITQVIALKHVMELIPTLRATLQSFKSSLFIEYHSLLVDSRYDEILSIINVVVHEDVHFEKGILQMRSQKLFAIKDGINVILDIARRSY---SEQIEALRDEV-QALSVEHALPLRVAFSNSRGFYIQLPLTNSSVKPRLSLPFIKVAIVKNFITCTTEKIMKFNERLKGALAEIYLTAELLLSELIKAIRVHMGVLYRLSEISATLDLLLSFAQV--SKMQNYIRPEFTD-----TLAIKNCRNPLLDRLSNKEAISNHVYAANLSNFTIVTGANMSGKSMYLRQIALVQIMGQIGCFIPAEYASFRLSDHLFTRIGVDDDIQSNSSTFTIEMREMSYIINTITDNSLVLIDELGRGTSFDEGLGICFAICEHL-LQTKAFIFIATHFRELSKLEILYPNVQNVNFEVKNLSESDGDENHLLFTYKCVRGVCPDFTNAMKLAKLSNLPKQ 2616
            L ++ +  DL ++ SL+  LN   T  G RLL   I QP  D+  I +R D VE L+N+ +L   L  +  +   +  L  +  +L +N+   + ++     +AL+   +++  L      +K  +  E  S++      EIL      +     F     +      F +K  ++  L     S      Q+E     V   L +E    L+   SNS G+Y+++   + +V    S   I +  +K+ +   + ++   NE       +       ++ E++K    ++G L++LS I A LD+L S A +       Y RP+  D        +KNCR+PL++  +N   I+N +       F I+TG NM GKS Y+R I L+ +M QIG F+P + A   + D + TRIG  D   +  STF  EM ++S+I+ T T  SL++IDELGRGTS  +G G+ ++I EH+  + KAF   ATHF EL+ L  ++ NV N++   + +       N L+F YK   G     +  +++AK S LP +
Sbjct:  297 LNILPSPNDLRKHDSLYGLLNCCRTASGERLLLQWIKQPLMDVNLINNRLDIVESLINDNKLRGCLYEE--NLRRIPDLQRITRRLQRNKG--NLQDIYKLYVALRQASDMLNLLNEHNGPYKCIIQSELSSVI-----QEILKDTENFIQMFTSFFD--FEAVKNHEFKVKCDVDESLKECENSMITLKSQMETESSRVSDKLGIESTKQLKFESSNSLGYYMRVSRKDENVLRNKSFISI-IETLKDGVKFHSTQMTLMNESYLQHRRDYEEYERSIIEEIMKITNKYVGSLHQLSSIIAKLDVLCSLATMVCGAPGTYARPKVVDDCKTRVFKVKNCRHPLVEMQNNMSYIANDISFDESRTFQIITGPNMGGKSTYIRSIGLISVMAQIGSFVPCDGAEISIFDRIMTRIGAGDCQLTGVSTFMAEMLDISWILKTATSKSLIIIDELGRGTSTFDGFGLAWSISEHIATELKAFSAFATHFHELTDLSKIHCNVNNLHVTAQTIG------NELIFMYKVEEGPAVR-SYGIEVAKASGLPDE 825

[Close]

BLAST of mutS protein homolog 4 vs. Planmine SMEST
Match: SMESG000006277.1 (SMESG000006277.1)

HSP 1 Score: 140.969 bits (354), Expect = 2.930e-34
Identity = 142/579 (24.53%), Postives = 264/579 (45.60%), Query Frame = 1

Query: 1030 KDLTENGSLFSALNFTTTNGGYRLLRANILQPSFDIPTITSRYDCVEELMN--NAELFFTLKSQIKHFVSLNHLLSLCVQLPKNQTVKSAENTITQVIA-LKHVMELIPTLRATLQSFKSSLFIEYHSLLVDSRYDEILSIINVVVHEDVHFEKGILQMRSQKLFAIKDGINVILDIARRSY-----------SEQIEALRDEVQALSVEHALPLRVAFSNSRGFYIQLPLTNSSVKPRLSLPFIKVAI-VKNFITCTTEKIMKFNERLKGALAEIYLTAELLLSELIKAIRVHMGVLYRLSEISATLDLLLSFAQVSKMQNYIRPEF--TDTLAIKNCRNPLLDRLSNKEAISNHVYAANLSN-FTIVTGANMSGKSMYLRQIALVQIMGQIGCFIPAEYASFRLSDHLFTRIGVDDDIQSNSSTFTIEMREMSYIINTITDNSLVLIDELGRGTSFDEGLGICFAICEHLLQTKA---FIFIATHFRELSKLEILYPNVQNVNFEVKNLSESDGDENHLLFTYKCVRGVCPDFTNAMKLAKLSNLPKQLLFEAEKIYGRLGDSNELIIEVKSQFIRN 2703
            KD  E  S+F  LN   +     +L + + +P  DI  I  R DCV+   N  N ++   L  ++K   ++  +L   +++  +  +    N + Q IA L  + E+   ++  L+  +           +++++ + L +I   + + +  E GI     QK F +K+G++  LD  +  Y            E+++   +++Q   + + LP         G+ + +P+ N+  + ++++P ++    + N +        K ++     L EI      ++  L ++I  +  +L    ++   LD LLS A  ++     RP F  +  + I+N R+PL +  SN   I N  Y+ +     TI++GAN SGKS+YL+QI ++ ++ QIG F+PA   S    + L TR+   +   S  STF +++ ++S        +S +LIDE G+G     G+ +  A    ++  K+    IF+ THF  L  L    P VQ  NF V      +   + L++ Y+ V G   + ++A++ A+L N+   +L  A              IEV   F +N
Sbjct:   77 KDTKEGLSIFHLLNNCHSKMASDMLHSWLRRPLTDISMIQKRLDCVDFFQNSQNQDVLQILLRKLKGVGNIKQIL---LRMKNSTALLPDWNVLIQSIAGLISIFEIFSAIKEPLEIKQK----------IEAKFTDKLYLIASWITKIIDTE-GI---EKQKRFVVKEGVDPYLDEKKSKYYHLPDLLSALAEEELKGFNNDIQICGIVY-LP-------QVGYLLTIPIENNENEQKINIPGMEYLFSMNNAVYYKNYTTKKLDKEFGDILYEIKDLETSIMHCLQESILEYTHMLLNCLDLVLELDCLLSLAIAARQIGGTRPLFETSGEIKIENGRHPLQEVFSN-PFIPNSTYSNDWDGKLTIISGANGSGKSVYLKQIGILIVLAQIGSFVPATKMSLTPQNALLTRLKSLESSLSGLSTFMVDLNQISLCCKKANAHSTILIDEFGKGAEMKSGISLIVAFLRFMVAKKSECPHIFVVTHFHRLFSLIQDLPKVQFKNFNV-----IEDKHSQLIYLYQLVDGHI-ECSHAIQAARLVNVSDNILQRA--------------IEVSDSFAKN 609

[Close]

BLAST of mutS protein homolog 4 vs. Planmine SMEST
Match: SMESG000006277.1 (SMESG000006277.1)

HSP 1 Score: 134.035 bits (336), Expect = 4.785e-32
Identity = 141/581 (24.27%), Postives = 260/581 (44.75%), Query Frame = 1

Query: 1030 KDLTENGSLFSALNFTTTNGGYRLLRANILQPSFDIPTITSRYDCVEELMN--NAELFFTLKSQIKHFVSLNHLLSLCVQLPKNQTVKSAENTITQVIA-LKHVMELIPTLRATLQSFKSSLFIEYHSLLVDSRYDEILSIINVVVHEDVHFEKGILQMRSQKLFAIKDGINVILDIARRSY-----------SEQIEALRDEVQALSVEHALPLRVAFSNSRGFYIQLPLTNSSVKPRLSLPFIKVAIVKNFITCTTEKIMKFNERLKGALAEIYLTAEL---LLSELIKAIRVHMGVLYRLSEISATLDLLLSFAQVSKMQNYIRPEF--TDTLAIKNCRNPLLDRLSNKEAISNHVYAANLSN-FTIVTGANMSGKSMYLRQIALVQIMGQIGCFIPAEYASFRLSDHLFTRIGVDDDIQSNSSTFTIEMREMSYIINTITDNSLVLIDELGRGTSFDEGLGICFAICEHLLQTKA---FIFIATHFRELSKLEILYPNVQNVNFEVKNLSESDGDENHLLFTYKCVRGVCPDFTNAMKLAKLSNLPKQLLFEAEKIYGRLGDSNELIIEVKSQFIRN 2703
            KD  E  S+F  LN   +     +L + + +P  DI  I  R DCV+   N  N ++   L  ++K   ++  +L   +++  +  +    N + Q IA L  + E+   ++  L+  +           +++++ + L +I   + + +  E GI     QK F +K+G++  LD  +  Y            E+++   +++Q   + + LP         G+ + +P+ N+  + ++++P ++     N                     + Y T  L   ++  L ++I  +  +L    ++   LD LLS A  ++     RP F  +  + I+N R+PL +  SN   I N  Y+ +     TI++GAN SGKS+YL+QI ++ ++ QIG F+PA   S    + L TR+   +   S  STF +++ ++S        +S +LIDE G+G     G+ +  A    ++  K+    IF+ THF  L  L    P VQ  NF V      +   + L++ Y+ V G   + ++A++ A+L N+   +L  A              IEV   F +N
Sbjct:   77 KDTKEGLSIFHLLNNCHSKMASDMLHSWLRRPLTDISMIQKRLDCVDFFQNSQNQDVLQILLRKLKGVGNIKQIL---LRMKNSTALLPDWNVLIQSIAGLISIFEIFSAIKEPLEIKQK----------IEAKFTDKLYLIASWITKIIDTE-GI---EKQKRFVVKEGVDPYLDEKKSKYYHLPDLLSALAEEELKGFNNDIQICGIVY-LP-------QVGYLLTIPIENNENEQKINIPGMEYLFSMN----------------NAVYYKNYTTKNLETSIMHCLQESILEYTHMLLNCLDLVLELDCLLSLAIAARQIGGTRPLFETSGEIKIENGRHPLQEVFSN-PFIPNSTYSNDWDGKLTIISGANGSGKSVYLKQIGILIVLAQIGSFVPATKMSLTPQNALLTRLKSLESSLSGLSTFMVDLNQISLCCKKANAHSTILIDEFGKGAEMKSGISLIVAFLRFMVAKKSECPHIFVVTHFHRLFSLIQDLPKVQFKNFNV-----IEDKHSQLIYLYQLVDGHI-ECSHAIQAARLVNVSDNILQRA--------------IEVSDSFAKN 595

The following BLAST results are available for this feature:

BLAST of mutS protein homolog 4 vs. Ensembl Human
BLAST of mutS protein homolog 4 vs. Ensembl Celegans
BLAST of mutS protein homolog 4 vs. Ensembl Fly
BLAST of mutS protein homolog 4 vs. Ensembl Zebrafish
BLAST of mutS protein homolog 4 vs. Ensembl Xenopus
BLAST of mutS protein homolog 4 vs. Ensembl Mouse
BLAST of mutS protein homolog 4 vs. UniProt/SwissProt
BLAST of mutS protein homolog 4 vs. TrEMBL
BLAST of mutS protein homolog 4 vs. Ensembl Cavefish
BLAST of mutS protein homolog 4 vs. Ensembl Sea Lamprey
BLAST of mutS protein homolog 4 vs. Ensembl Yeast
BLAST of mutS protein homolog 4 vs. Ensembl Nematostella
BLAST of mutS protein homolog 4 vs. Ensembl Medaka
BLAST of mutS protein homolog 4 vs. Planmine SMEST

BLAST of mutS protein homolog 4 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
MSH4	0.000e+0	44.74	mutS homolog 4 [Source:HGNC Symbol;Acc:HGNC:7327]	[more]
MSH2	5.591e-54	28.49	mutS homolog 2 [Source:HGNC Symbol;Acc:HGNC:7325]	[more]
MSH2	6.214e-54	28.49	mutS homolog 2 [Source:HGNC Symbol;Acc:HGNC:7325]	[more]
MSH2	6.370e-54	28.49	mutS homolog 2 [Source:HGNC Symbol;Acc:HGNC:7325]	[more]
MSH2	6.576e-54	28.49	mutS homolog 2 [Source:HGNC Symbol;Acc:HGNC:7325]	[more]

BLAST of mutS protein homolog 4 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5


Match Name	E-value	Identity	Description
him-14	1.714e-105	30.52	MutS protein homolog him-14 [Source:UniProtKB/Swi...	[more]
msh-2	3.549e-38	25.43	MSH (MutS Homolog) family [Source:UniProtKB/TrEMB...	[more]
msh-6	4.071e-31	26.08	MSH (MutS Homolog) family [Source:UniProtKB/TrEMB...	[more]
msh-5	5.595e-24	23.91	MutS protein homolog 5 [Source:UniProtKB/Swiss-Pr...	[more]
msh-5	1.158e-21	26.43	MutS protein homolog 5 [Source:UniProtKB/Swiss-Pr...	[more]

BLAST of mutS protein homolog 4 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5


Match Name	E-value	Identity	Description
spel1	2.144e-40	32.71	gene:FBgn0015546 transcript:FBtr0344018	[more]
spel1	2.144e-40	32.71	gene:FBgn0015546 transcript:FBtr0344019	[more]
spel1	2.144e-40	32.71	gene:FBgn0015546 transcript:FBtr0080630	[more]
spel1	2.144e-40	32.71	gene:FBgn0015546 transcript:FBtr0309281	[more]
Msh6	1.145e-26	34.52	gene:FBgn0036486 transcript:FBtr0075646	[more]

BLAST of mutS protein homolog 4 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
msh4	0.000e+0	45.85	mutS homolog 4 [Source:ZFIN;Acc:ZDB-GENE-131121-64...	[more]
msh4	0.000e+0	42.44	mutS homolog 4 [Source:ZFIN;Acc:ZDB-GENE-131121-64...	[more]
msh4	0.000e+0	42.58	mutS homolog 4 [Source:ZFIN;Acc:ZDB-GENE-131121-64...	[more]
msh2	4.888e-51	27.34	mutS homolog 2 (E. coli) [Source:ZFIN;Acc:ZDB-GENE...	[more]
msh2	4.888e-51	27.34	mutS homolog 2 (E. coli) [Source:ZFIN;Acc:ZDB-GENE...	[more]

BLAST of mutS protein homolog 4 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ak7	0.000e+0	43.19	adenylate kinase 7 [Source:Xenbase;Acc:XB-GENE-953...	[more]
ak7	1.002e-82	47.91	adenylate kinase 7 [Source:Xenbase;Acc:XB-GENE-953...	[more]
MSH2	1.335e-50	26.74	mutS homolog 2 [Source:NCBI gene;Acc:100380043]	[more]
MSH2	6.160e-50	27.26	mutS homolog 2 [Source:NCBI gene;Acc:100380043]	[more]
MSH2	7.354e-49	26.95	mutS homolog 2 [Source:NCBI gene;Acc:100380043]	[more]

BLAST of mutS protein homolog 4 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Msh4	0.000e+0	44.20	mutS homolog 4 [Source:MGI Symbol;Acc:MGI:1860077]	[more]
Msh4	0.000e+0	44.20	mutS homolog 4 [Source:MGI Symbol;Acc:MGI:1860077]	[more]
Msh4	0.000e+0	43.76	mutS homolog 4 [Source:MGI Symbol;Acc:MGI:1860077]	[more]
Msh3	2.361e-50	27.84	mutS homolog 3 [Source:MGI Symbol;Acc:MGI:109519]	[more]
Msh3	3.309e-49	27.96	mutS homolog 3 [Source:MGI Symbol;Acc:MGI:109519]	[more]

BLAST of mutS protein homolog 4 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|O15457\|MSH4_HUMAN	0.000e+0	44.74	MutS protein homolog 4 OS=Homo sapiens OX=9606 GN=...	[more]
sp\|Q99MT2\|MSH4_MOUSE	0.000e+0	44.20	MutS protein homolog 4 OS=Mus musculus OX=10090 GN...	[more]
sp\|F4JP48\|MSH4_ARATH	3.696e-122	34.91	DNA mismatch repair protein MSH4 OS=Arabidopsis th...	[more]
sp\|Q23405\|HIM14_CAEEL	2.180e-104	30.52	MutS protein homolog him-14 OS=Caenorhabditis eleg...	[more]
sp\|P40965\|MSH4_YEAST	9.765e-97	33.48	MutS protein homolog 4 OS=Saccharomyces cerevisiae...	[more]

BLAST of mutS protein homolog 4 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
W4ZC78	0.000e+0	49.86	DNA_MISMATCH_REPAIR_2 domain-containing protein OS...	[more]
A0A0L8GSV3	0.000e+0	47.57	DNA_MISMATCH_REPAIR_2 domain-containing protein OS...	[more]
A0A1S3J8M3	0.000e+0	48.26	mutS protein homolog 4 OS=Lingula unguis OX=7574 G...	[more]
A0A210Q4E9	0.000e+0	47.10	MutS protein-like 4 OS=Mizuhopecten yessoensis OX=...	[more]
A0A5N3WK57	0.000e+0	45.01	Uncharacterized protein OS=Muntiacus muntjak OX=98...	[more]

BLAST of mutS protein homolog 4 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
msh4	0.000e+0	44.80	mutS homolog 4 [Source:ZFIN;Acc:ZDB-GENE-131121-64...	[more]
msh2	7.105e-52	26.94	mutS homolog 2 [Source:NCBI gene;Acc:103047089]	[more]
msh3	6.760e-46	26.44	mutS homolog 3 [Source:NCBI gene;Acc:103037699]	[more]
msh3	6.760e-46	26.44	mutS homolog 3 [Source:NCBI gene;Acc:103037699]	[more]
msh3	3.413e-34	35.95	mutS homolog 3 [Source:NCBI gene;Acc:103037699]	[more]

BLAST of mutS protein homolog 4 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 3


Match Name	E-value	Identity	Description
msh3	3.962e-42	25.33	mutS homolog 3 (E. coli) [Source:ZFIN;Acc:ZDB-GENE...	[more]
msh6	3.139e-25	34.52	mutS homolog 6 (E. coli) [Source:ZFIN;Acc:ZDB-GENE...	[more]
msh2	1.744e-6	28.64	mutS homolog 2 (E. coli) [Source:ZFIN;Acc:ZDB-GENE...	[more]

BLAST of mutS protein homolog 4 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 5


Match Name	E-value	Identity	Description
MSH4	1.406e-98	33.48	Protein involved in meiotic recombination; require...	[more]
MSH2	2.830e-48	28.19	Protein that binds to DNA mismatches; forms hetero...	[more]
MSH3	3.431e-48	29.01	Mismatch repair protein; forms dimers with Msh2p t...	[more]
MSH1	3.078e-34	33.98	DNA-binding protein of the mitochondria; involved ...	[more]
MSH6	2.753e-32	23.06	Protein required for mismatch repair in mitosis an...	[more]

BLAST of mutS protein homolog 4 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5


Match Name	E-value	Identity	Description
EDO35291	0.000e+0	45.58	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO38319	2.931e-51	26.87	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO26509	7.175e-48	39.00	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO38799	9.914e-40	25.17	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO48759	9.626e-38	27.55	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of mutS protein homolog 4 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5


Match Name	E-value	Identity	Description
msh4	0.000e+0	46.80	mutS homolog 4 [Source:NCBI gene;Acc:101160275]	[more]
msh4	0.000e+0	46.10	mutS homolog 4 [Source:NCBI gene;Acc:101160275]	[more]
msh3	2.792e-52	26.09	mutS homolog 3 [Source:NCBI gene;Acc:101156254]	[more]
msh2	1.830e-51	27.05	mutS homolog 2 [Source:NCBI gene;Acc:101167993]	[more]
msh3	2.298e-45	25.31	mutS homolog 3 [Source:NCBI gene;Acc:101156254]	[more]

BLAST of mutS protein homolog 4 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5


Match Name	E-value	Identity	Description
SMESG000019326.1	0.000e+0	98.03	SMESG000019326.1	[more]
SMESG000019325.1	0.000e+0	90.42	SMESG000019325.1	[more]
SMESG000016751.1	8.609e-53	29.20	SMESG000016751.1	[more]
SMESG000006277.1	2.930e-34	24.53	SMESG000006277.1	[more]
SMESG000006277.1	4.785e-32	24.27	SMESG000006277.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30028928 ID=SMED30028928|Name=mutS protein homolog 4|organism=Schmidtea mediterranea sexual|type=transcript|length=2984bp
CAAAATTATTTAAGTGAGAATATCAATTTTTGTTTAGTGATTGATATTAC
CATAAATCTAGTTCGTAAATTTCAAAGCGATGAAAAAACAACTATTTCGA
CATTTATTCGAAACTCCAAATGAAGCTTTTCAAGTGACAATCTAGTTACA
AACAATAAAAACGATTTTATTTTTAAAACTCCGAAAAGCAGAGGAATGGA
ACCAAGTTGTTCATACCAAGACACTGATACTATGAGCCTTAAAACATGTC
CAAATTTGAATCACAAGTTAAAGAAAACGATTGCATTTTCAACAAGTATT
CTTGATAAGAAAAAATTTAGATCAGAAGTTACTCCGTATAAACGTACAAT
AAACTTACCTTTGAAGTATTTGTCAACAGGAAGCAAAAGCGATCTGTCAA
GAATTGTATCTAATAAATTAGTAAGAAAAAGTAAATTGCCCACGAAAACA
TCCACTACACTTCTAAGTACGGGACCTTCAACTTCAACAACAACTAACAC
AAAACGAACTAGTGATTCCTGTTTATTAATTGAAGGAAGGGGGGTTGCAT
CAGGAGAAATTGGTATAGCAAGCGTTGATTTAAAAAACCCTGAGCTTGAA
TTATCACAATTTTCTGATTCCATTGGCTATTCTCGAACTTTATCTAAATT
ATATTTGAAAGATCCAGTTGAGATCGTTTTTCCTCACACTATGTGTGAAA
ATGGAGTCAGATCGAAATTGTTTCAAATCGTTTCGGAATTTATGCATAAA
TCGTCAATAACAACAATTCATCGCCGTTATTACAATGATAAAAACGGAAA
GGAAATTATTCAGCATCTTTGCCATAAAGATTACACTTCATCAATACTTT
ATGAAAGCAGGGAAAAATATTATGCTCTAGCTGCATGTGCTGCAATAATT
AAATATGTTGAATTTATTCAAAATATATTATTTGCCCCTGGATCCTTACA
GATTATATTTTCTGGATCAGTAAAATGTGCGATAATTGATATTGCTTCAG
TAAGAAATCTTGAATTAGTTGAAAATTCGAAAGATCTCACTGAAAACGGC
TCGCTATTTTCTGCTTTAAATTTTACTACAACTAATGGTGGATACCGACT
TCTTCGTGCTAACATTTTGCAACCGTCTTTTGATATTCCAACAATTACCT
CTCGATATGATTGTGTGGAAGAATTAATGAACAATGCTGAACTATTTTTC
ACTTTAAAATCTCAAATAAAACATTTTGTGTCCTTAAATCATTTACTTTC
TCTATGCGTTCAACTCCCAAAAAATCAAACTGTTAAAAGTGCCGAGAATA
CAATAACTCAAGTTATTGCACTGAAACATGTAATGGAATTAATTCCAACT
CTAAGAGCGACTCTACAATCCTTTAAAAGCTCATTGTTTATAGAATATCA
TTCGTTACTCGTGGATTCCAGATATGATGAAATTCTTTCAATTATTAATG
TAGTGGTTCACGAAGATGTGCATTTTGAAAAAGGAATTCTTCAAATGAGA
TCTCAGAAGCTTTTTGCAATTAAAGATGGAATTAATGTCATATTAGATAT
AGCTCGACGTTCTTATTCTGAACAAATTGAAGCATTGCGGGACGAAGTAC
AAGCGCTATCTGTAGAACATGCTCTTCCACTTAGAGTAGCTTTCAGTAAT
TCTCGGGGATTCTACATTCAGTTACCGTTGACAAATAGTTCAGTTAAACC
TCGATTAAGTTTACCATTCATAAAAGTGGCGATTGTTAAAAATTTTATTA
CATGCACTACCGAAAAAATTATGAAATTTAACGAAAGGCTTAAAGGTGCG
CTAGCAGAAATTTATTTAACTGCAGAATTGCTGCTCTCTGAGTTAATAAA
GGCAATTCGGGTGCATATGGGAGTGTTATATAGGTTATCTGAAATATCTG
CAACTTTAGATTTATTATTGTCGTTTGCTCAAGTTAGTAAAATGCAAAAT
TATATCCGTCCTGAATTTACCGATACACTTGCAATAAAAAATTGTCGTAA
TCCTTTGCTTGACAGGTTATCAAATAAAGAAGCAATATCTAATCACGTGT
ATGCAGCAAATCTATCGAATTTTACCATCGTTACCGGTGCAAATATGAGT
GGTAAATCAATGTATCTACGACAAATTGCTTTAGTTCAGATAATGGGCCA
AATAGGATGTTTTATTCCAGCAGAATATGCATCTTTTCGTTTGAGCGATC
ATTTGTTTACGCGAATCGGAGTAGATGATGATATCCAATCAAATTCTTCT
ACTTTCACAATTGAGATGAGAGAAATGAGCTACATTATCAATACCATTAC
CGATAATTCTTTAGTTCTTATAGACGAGTTAGGAAGAGGAACAAGTTTTG
ATGAAGGCCTTGGAATATGTTTTGCTATTTGTGAACATTTATTACAAACT
AAAGCATTTATATTCATAGCGACTCATTTCAGGGAGCTTTCGAAATTGGA
AATTCTTTATCCAAACGTTCAAAATGTGAATTTTGAAGTAAAAAATTTAT
CCGAATCTGATGGCGATGAGAATCATTTGCTTTTTACATATAAATGTGTC
AGAGGAGTTTGTCCAGATTTTACGAATGCGATGAAATTGGCCAAATTATC
GAATCTTCCGAAACAACTTTTATTCGAAGCTGAAAAGATCTATGGTAGAC
TCGGTGATTCTAACGAGCTGATAATTGAAGTAAAGTCTCAGTTTATAAGG
AACATCCATAAAGGACGTCCTCTGGGAAAGGAGAGAGGGGTCTTTACAAA
AGGGGGCATGATGGGACAATGGGAAAACGAAAAAAATACAAATTCAATTG
CGAGTGATTATGAAATATGCAAATTATCTGCAAAAATAGAATATCTTGCA
AAAAATGTTACTGTTGACACGCCGGAGGTAAATTTTTGTTTAAAATCTTT
ACAAAATCAATGCAGGGTGACTTTTGAAAAGTTAAACAAACAATAAATTG
CATTTGTATTGTTGTTAAATACATTTTCTATTCC

protein sequence of SMED30028928-orf-1

>SMED30028928-orf-1 ID=SMED30028928-orf-1|Name=SMED30028928-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=917bp
MEPSCSYQDTDTMSLKTCPNLNHKLKKTIAFSTSILDKKKFRSEVTPYKR
TINLPLKYLSTGSKSDLSRIVSNKLVRKSKLPTKTSTTLLSTGPSTSTTT
NTKRTSDSCLLIEGRGVASGEIGIASVDLKNPELELSQFSDSIGYSRTLS
KLYLKDPVEIVFPHTMCENGVRSKLFQIVSEFMHKSSITTIHRRYYNDKN
GKEIIQHLCHKDYTSSILYESREKYYALAACAAIIKYVEFIQNILFAPGS
LQIIFSGSVKCAIIDIASVRNLELVENSKDLTENGSLFSALNFTTTNGGY
RLLRANILQPSFDIPTITSRYDCVEELMNNAELFFTLKSQIKHFVSLNHL
LSLCVQLPKNQTVKSAENTITQVIALKHVMELIPTLRATLQSFKSSLFIE
YHSLLVDSRYDEILSIINVVVHEDVHFEKGILQMRSQKLFAIKDGINVIL
DIARRSYSEQIEALRDEVQALSVEHALPLRVAFSNSRGFYIQLPLTNSSV
KPRLSLPFIKVAIVKNFITCTTEKIMKFNERLKGALAEIYLTAELLLSEL
IKAIRVHMGVLYRLSEISATLDLLLSFAQVSKMQNYIRPEFTDTLAIKNC
RNPLLDRLSNKEAISNHVYAANLSNFTIVTGANMSGKSMYLRQIALVQIM
GQIGCFIPAEYASFRLSDHLFTRIGVDDDIQSNSSTFTIEMREMSYIINT
ITDNSLVLIDELGRGTSFDEGLGICFAICEHLLQTKAFIFIATHFRELSK
LEILYPNVQNVNFEVKNLSESDGDENHLLFTYKCVRGVCPDFTNAMKLAK
LSNLPKQLLFEAEKIYGRLGDSNELIIEVKSQFIRNIHKGRPLGKERGVF
TKGGMMGQWENEKNTNSIASDYEICKLSAKIEYLAKNVTVDTPEVNFCLK
SLQNQCRVTFEKLNKQ*

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000020	protonephridia
PLANA:0000099	neuron
PLANA:0003116	parenchymal cell

Vocabulary: **INTERPRO**
Term	Definition
IPR000432	DNA_mismatch_repair_MutS_C
IPR007696	DNA_mismatch_repair_MutS_core
IPR027417	P-loop_NTPase
IPR007860	DNA_mmatch_repair_MutS_con_dom
IPR007861	DNA_mismatch_repair_MutS_clamp

Vocabulary: **molecular function**
Term	Definition
GO:0005524	ATP binding
GO:0030983	mismatched DNA binding
GO:0003677	DNA binding

Vocabulary: **biological process**
Term	Definition
GO:0006298	mismatch repair
GO:0001541	ovarian follicle development
GO:0006281	DNA repair
GO:0006974	cellular response to DNA damage stimulus
GO:0007126	meiotic nuclear division
GO:0007129	synapsis
GO:0007283	spermatogenesis
GO:0007292	female gamete generation

Vocabulary: **cellular component**
Term	Definition
GO:0000793	condensed chromosome
GO:0000794	condensed nuclear chromosome
GO:0000795	synaptonemal complex
GO:0005634	nucleus
GO:0005713	recombination nodule
GO:0032301	MutSalpha complex