Bromodomain containing 2
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30028894 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 4
Homology
BLAST of Bromodomain containing 2 vs. Ensembl Human
Match: BRDT (bromodomain testis associated [Source:HGNC Symbol;Acc:HGNC:1105]) HSP 1 Score: 160.229 bits (404), Expect = 2.123e-41 Identity = 111/354 (31.36%), Postives = 174/354 (49.15%), Query Frame = 2
Query: 203 TNRLQFIKKKILPQLMRHKYSFPFLHPVDHAALNIPDYPKIIHYPMDFTTVKNRLIKKFYYNADECITDIRLVFQNCYIFNPPEIDLISMTLTLENIFNSKLDKLPSQEXXXXXXXXXXXXXXXXXXXXXXXEPVCDIKKSLRPTTKRLKXXXXXXXXXXXXXXXCSISPDAK-----------SKAKKRKVE------SCYDLSPTPSPSISLKNESLDEIPIKPKLSEEL----KMCSNILRDIS-SNRYRHLNDM---------------FMEPVAVRFPNLSDYSSIIKKPMDLSTIRKNLDDGSYKTKNDFSEDVKLIFDNCYDYNGKDSDISKLAKDLQNIFDELFSK 1153
TN+LQ+++K +L L +H +S+PF PVD L +PDY II PMD T+K RL K+Y A ECI D +F NCY++N P D++ M LE +F KL ++P +E + K +I S+ E K S T K K + T+ S ++ A +K KRK + S S SP+ + K+ +L PIK + + + + N+++ + + + RH +++ F PV V L +Y ++K PMDL TI++ +D+ YK F+ DV+L+F NCY YN D ++ +A+ LQ++F+ FSK
Sbjct: 29 TNQLQYLQKVVLKDLWKHSFSWPFQRPVDAVKLQLPDYYTIIKNPMDLNTIKKRLENKYYAKASECIEDFNTMFSNCYLYNKPGDDIVLMAQALEKLFMQKLSQMPQEEQVVGVKERIKKGTQQNIAVSSAKE-----KSSPSATEKVFKQQEIPSVFPKTSISPLNVVQGASVNSSSQTAAQVTKGVKRKADTTTPATSAVKASSEFSPTFTEKSVALP--PIKENMPKNVLPDSQQQYNVVKTVKVTEQLRHCSEILKEMLAKKHFSYAWPFYNPVDVNALGLHNYYDVVKNPMDLGTIKEKMDNQEYKDAYKFAADVRLMFMNCYKYNPPDHEVVTMARMLQDVFETHFSK 375 HSP 2 Score: 80.1073 bits (196), Expect = 5.862e-15 Identity = 34/100 (34.00%), Postives = 64/100 (64.00%), Query Frame = 2
Query: 230 KILPQLMRHK---YSFPFLHPVDHAALNIPDYPKIIHYPMDFTTVKNRLIKKFYYNADECITDIRLVFQNCYIFNPPEIDLISMTLTLENIFNSKLDKLP 520
+IL +++ K Y++PF +PVD AL + +Y ++ PMD T+K ++ + Y +A + D+RL+F NCY +NPP+ ++++M L+++F + K+P
Sbjct: 278 EILKEMLAKKHFSYAWPFYNPVDVNALGLHNYYDVVKNPMDLGTIKEKMDNQEYKDAYKFAADVRLMFMNCYKYNPPDHEVVTMARMLQDVFETHFSKIP 377 HSP 3 Score: 63.5438 bits (153), Expect = 9.945e-10 Identity = 49/152 (32.24%), Postives = 75/152 (49.34%), Query Frame = 2
Query: 863 ILRDISSNRYRH-LNDMFMEPVAVRFPNLSDYSSIIKKPMDLSTIRKNLDDGSYKTKNDFSEDVKLIFDNCYDYNGKDSDISKLAKDLQNIFDELFSKQFNLSKPQPSQVQNSKIKSESVNEDTLQLLQKIHKEQKSLVETHNKVAEKIIKQ 1315
+L+D+ ++H + F PV L DY +IIK PMDL+TI+K L++ Y ++ ED +F NCY YN DI +A+ L+ +F + S+ PQ QV K E + + T Q + ++KS EK+ KQ
Sbjct: 39 VLKDL----WKHSFSWPFQRPVDAVKLQLPDYYTIIKNPMDLNTIKKRLENKYYAKASECIEDFNTMFSNCYLYNKPGDDIVLMAQALEKLFMQKLSQM-----PQEEQVVGVK---ERIKKGTQQNIAVSSAKEKS----SPSATEKVFKQ 174
BLAST of Bromodomain containing 2 vs. Ensembl Human
Match: BRDT (bromodomain testis associated [Source:HGNC Symbol;Acc:HGNC:1105]) HSP 1 Score: 161.384 bits (407), Expect = 8.782e-40 Identity = 111/354 (31.36%), Postives = 174/354 (49.15%), Query Frame = 2
Query: 203 TNRLQFIKKKILPQLMRHKYSFPFLHPVDHAALNIPDYPKIIHYPMDFTTVKNRLIKKFYYNADECITDIRLVFQNCYIFNPPEIDLISMTLTLENIFNSKLDKLPSQEXXXXXXXXXXXXXXXXXXXXXXXEPVCDIKKSLRPTTKRLKXXXXXXXXXXXXXXXCSISPDAK-----------SKAKKRKVE------SCYDLSPTPSPSISLKNESLDEIPIKPKLSEEL----KMCSNILRDIS-SNRYRHLNDMFME---------------PVAVRFPNLSDYSSIIKKPMDLSTIRKNLDDGSYKTKNDFSEDVKLIFDNCYDYNGKDSDISKLAKDLQNIFDELFSK 1153
TN+LQ+++K +L L +H +S+PF PVD L +PDY II PMD T+K RL K+Y A ECI D +F NCY++N P D++ M LE +F KL ++P +E + K +I S+ E K S T K K + T+ S ++ A +K KRK + S S SP+ + K+ +L PIK + + + + N+++ + + + RH +++ E PV V L +Y ++K PMDL TI++ +D+ YK F+ DV+L+F NCY YN D ++ +A+ LQ++F+ FSK
Sbjct: 29 TNQLQYLQKVVLKDLWKHSFSWPFQRPVDAVKLQLPDYYTIIKNPMDLNTIKKRLENKYYAKASECIEDFNTMFSNCYLYNKPGDDIVLMAQALEKLFMQKLSQMPQEEQVVGVKERIKKGTQQNIAVSSAKE-----KSSPSATEKVFKQQEIPSVFPKTSISPLNVVQGASVNSSSQTAAQVTKGVKRKADTTTPATSAVKASSEFSPTFTEKSVALP--PIKENMPKNVLPDSQQQYNVVKTVKVTEQLRHCSEILKEMLAKKHFSYAWPFYNPVDVNALGLHNYYDVVKNPMDLGTIKEKMDNQEYKDAYKFAADVRLMFMNCYKYNPPDHEVVTMARMLQDVFETHFSK 375 HSP 2 Score: 106.686 bits (265), Expect = 8.657e-23 Identity = 47/74 (63.51%), Postives = 63/74 (85.14%), Query Frame = 2
Query: 1685 EDCKPMSYDDKRKLSMDINQLPGDKLGRIVQIIQEREPTLRDSNPDEIEIDFEVLHPVTLRELQKFVQSVLSRQ 1906
++ KPM+YD+KR+LS++IN+LPGDKLGR+V IIQ REP+L +SNPDEIEIDFE L TLREL+K+V + L ++
Sbjct: 505 DNAKPMNYDEKRQLSLNINKLPGDKLGRVVHIIQSREPSLSNSNPDEIEIDFETLKASTLRELEKYVSACLRKR 578 HSP 3 Score: 82.4185 bits (202), Expect = 2.946e-15 Identity = 34/100 (34.00%), Postives = 64/100 (64.00%), Query Frame = 2
Query: 230 KILPQLMRHK---YSFPFLHPVDHAALNIPDYPKIIHYPMDFTTVKNRLIKKFYYNADECITDIRLVFQNCYIFNPPEIDLISMTLTLENIFNSKLDKLP 520
+IL +++ K Y++PF +PVD AL + +Y ++ PMD T+K ++ + Y +A + D+RL+F NCY +NPP+ ++++M L+++F + K+P
Sbjct: 278 EILKEMLAKKHFSYAWPFYNPVDVNALGLHNYYDVVKNPMDLGTIKEKMDNQEYKDAYKFAADVRLMFMNCYKYNPPDHEVVTMARMLQDVFETHFSKIP 377 HSP 4 Score: 63.929 bits (154), Expect = 1.341e-9 Identity = 39/110 (35.45%), Postives = 59/110 (53.64%), Query Frame = 2
Query: 863 ILRDISSNRYRH-LNDMFMEPVAVRFPNLSDYSSIIKKPMDLSTIRKNLDDGSYKTKNDFSEDVKLIFDNCYDYNGKDSDISKLAKDLQNIFDELFSKQFNLSKPQPSQV 1189
+L+D+ ++H + F PV L DY +IIK PMDL+TI+K L++ Y ++ ED +F NCY YN DI +A+ L+ +F + S+ PQ QV
Sbjct: 39 VLKDL----WKHSFSWPFQRPVDAVKLQLPDYYTIIKNPMDLNTIKKRLENKYYAKASECIEDFNTMFSNCYLYNKPGDDIVLMAQALEKLFMQKLSQM-----PQEEQV 139
BLAST of Bromodomain containing 2 vs. Ensembl Human
Match: BRDT (bromodomain testis associated [Source:HGNC Symbol;Acc:HGNC:1105]) HSP 1 Score: 161.384 bits (407), Expect = 8.782e-40 Identity = 111/354 (31.36%), Postives = 174/354 (49.15%), Query Frame = 2
Query: 203 TNRLQFIKKKILPQLMRHKYSFPFLHPVDHAALNIPDYPKIIHYPMDFTTVKNRLIKKFYYNADECITDIRLVFQNCYIFNPPEIDLISMTLTLENIFNSKLDKLPSQEXXXXXXXXXXXXXXXXXXXXXXXEPVCDIKKSLRPTTKRLKXXXXXXXXXXXXXXXCSISPDAK-----------SKAKKRKVE------SCYDLSPTPSPSISLKNESLDEIPIKPKLSEEL----KMCSNILRDIS-SNRYRHLNDMFME---------------PVAVRFPNLSDYSSIIKKPMDLSTIRKNLDDGSYKTKNDFSEDVKLIFDNCYDYNGKDSDISKLAKDLQNIFDELFSK 1153
TN+LQ+++K +L L +H +S+PF PVD L +PDY II PMD T+K RL K+Y A ECI D +F NCY++N P D++ M LE +F KL ++P +E + K +I S+ E K S T K K + T+ S ++ A +K KRK + S S SP+ + K+ +L PIK + + + + N+++ + + + RH +++ E PV V L +Y ++K PMDL TI++ +D+ YK F+ DV+L+F NCY YN D ++ +A+ LQ++F+ FSK
Sbjct: 29 TNQLQYLQKVVLKDLWKHSFSWPFQRPVDAVKLQLPDYYTIIKNPMDLNTIKKRLENKYYAKASECIEDFNTMFSNCYLYNKPGDDIVLMAQALEKLFMQKLSQMPQEEQVVGVKERIKKGTQQNIAVSSAKE-----KSSPSATEKVFKQQEIPSVFPKTSISPLNVVQGASVNSSSQTAAQVTKGVKRKADTTTPATSAVKASSEFSPTFTEKSVALP--PIKENMPKNVLPDSQQQYNVVKTVKVTEQLRHCSEILKEMLAKKHFSYAWPFYNPVDVNALGLHNYYDVVKNPMDLGTIKEKMDNQEYKDAYKFAADVRLMFMNCYKYNPPDHEVVTMARMLQDVFETHFSK 375 HSP 2 Score: 106.686 bits (265), Expect = 8.657e-23 Identity = 47/74 (63.51%), Postives = 63/74 (85.14%), Query Frame = 2
Query: 1685 EDCKPMSYDDKRKLSMDINQLPGDKLGRIVQIIQEREPTLRDSNPDEIEIDFEVLHPVTLRELQKFVQSVLSRQ 1906
++ KPM+YD+KR+LS++IN+LPGDKLGR+V IIQ REP+L +SNPDEIEIDFE L TLREL+K+V + L ++
Sbjct: 505 DNAKPMNYDEKRQLSLNINKLPGDKLGRVVHIIQSREPSLSNSNPDEIEIDFETLKASTLRELEKYVSACLRKR 578 HSP 3 Score: 82.4185 bits (202), Expect = 2.946e-15 Identity = 34/100 (34.00%), Postives = 64/100 (64.00%), Query Frame = 2
Query: 230 KILPQLMRHK---YSFPFLHPVDHAALNIPDYPKIIHYPMDFTTVKNRLIKKFYYNADECITDIRLVFQNCYIFNPPEIDLISMTLTLENIFNSKLDKLP 520
+IL +++ K Y++PF +PVD AL + +Y ++ PMD T+K ++ + Y +A + D+RL+F NCY +NPP+ ++++M L+++F + K+P
Sbjct: 278 EILKEMLAKKHFSYAWPFYNPVDVNALGLHNYYDVVKNPMDLGTIKEKMDNQEYKDAYKFAADVRLMFMNCYKYNPPDHEVVTMARMLQDVFETHFSKIP 377 HSP 4 Score: 63.929 bits (154), Expect = 1.341e-9 Identity = 39/110 (35.45%), Postives = 59/110 (53.64%), Query Frame = 2
Query: 863 ILRDISSNRYRH-LNDMFMEPVAVRFPNLSDYSSIIKKPMDLSTIRKNLDDGSYKTKNDFSEDVKLIFDNCYDYNGKDSDISKLAKDLQNIFDELFSKQFNLSKPQPSQV 1189
+L+D+ ++H + F PV L DY +IIK PMDL+TI+K L++ Y ++ ED +F NCY YN DI +A+ L+ +F + S+ PQ QV
Sbjct: 39 VLKDL----WKHSFSWPFQRPVDAVKLQLPDYYTIIKNPMDLNTIKKRLENKYYAKASECIEDFNTMFSNCYLYNKPGDDIVLMAQALEKLFMQKLSQM-----PQEEQV 139
BLAST of Bromodomain containing 2 vs. Ensembl Human
Match: BRDT (bromodomain testis associated [Source:HGNC Symbol;Acc:HGNC:1105]) HSP 1 Score: 112.464 bits (280), Expect = 6.795e-28 Identity = 49/109 (44.95%), Postives = 69/109 (63.30%), Query Frame = 2
Query: 203 TNRLQFIKKKILPQLMRHKYSFPFLHPVDHAALNIPDYPKIIHYPMDFTTVKNRLIKKFYYNADECITDIRLVFQNCYIFNPPEIDLISMTLTLENIFNSKLDKLPSQE 529
TN+LQ+++K +L L +H +S+PF PVD L +PDY II PMD T+K RL K+Y A ECI D +F NCY++N P D++ M LE +F KL ++P +E
Sbjct: 29 TNQLQYLQKVVLKDLWKHSFSWPFQRPVDAVKLQLPDYYTIIKNPMDLNTIKKRLENKYYAKASECIEDFNTMFSNCYLYNKPGDDIVLMAQALEKLFMQKLSQMPQEE 137 HSP 2 Score: 63.5438 bits (153), Expect = 7.576e-11 Identity = 49/152 (32.24%), Postives = 75/152 (49.34%), Query Frame = 2
Query: 863 ILRDISSNRYRH-LNDMFMEPVAVRFPNLSDYSSIIKKPMDLSTIRKNLDDGSYKTKNDFSEDVKLIFDNCYDYNGKDSDISKLAKDLQNIFDELFSKQFNLSKPQPSQVQNSKIKSESVNEDTLQLLQKIHKEQKSLVETHNKVAEKIIKQ 1315
+L+D+ ++H + F PV L DY +IIK PMDL+TI+K L++ Y ++ ED +F NCY YN DI +A+ L+ +F + S+ PQ QV K E + + T Q + ++KS EK+ KQ
Sbjct: 39 VLKDL----WKHSFSWPFQRPVDAVKLQLPDYYTIIKNPMDLNTIKKRLENKYYAKASECIEDFNTMFSNCYLYNKPGDDIVLMAQALEKLFMQKLSQM-----PQEEQVVGVK---ERIKKGTQQNIAVSSAKEKS----SPSATEKVFKQ 174
BLAST of Bromodomain containing 2 vs. Ensembl Human
Match: BRDT (bromodomain testis associated [Source:HGNC Symbol;Acc:HGNC:1105]) HSP 1 Score: 112.849 bits (281), Expect = 1.264e-27 Identity = 49/109 (44.95%), Postives = 69/109 (63.30%), Query Frame = 2
Query: 203 TNRLQFIKKKILPQLMRHKYSFPFLHPVDHAALNIPDYPKIIHYPMDFTTVKNRLIKKFYYNADECITDIRLVFQNCYIFNPPEIDLISMTLTLENIFNSKLDKLPSQE 529
TN+LQ+++K +L L +H +S+PF PVD L +PDY II PMD T+K RL K+Y A ECI D +F NCY++N P D++ M LE +F KL ++P +E
Sbjct: 29 TNQLQYLQKVVLKDLWKHSFSWPFQRPVDAVKLQLPDYYTIIKNPMDLNTIKKRLENKYYAKASECIEDFNTMFSNCYLYNKPGDDIVLMAQALEKLFMQKLSQMPQEE 137 HSP 2 Score: 64.3142 bits (155), Expect = 6.154e-11 Identity = 51/153 (33.33%), Postives = 78/153 (50.98%), Query Frame = 2
Query: 863 ILRDISSNRYRH-LNDMFMEPV-AVRFPNLSDYSSIIKKPMDLSTIRKNLDDGSYKTKNDFSEDVKLIFDNCYDYNGKDSDISKLAKDLQNIFDELFSKQFNLSKPQPSQVQNSKIKSESVNEDTLQLLQKIHKEQKSLVETHNKVAEKIIKQ 1315
+L+D+ ++H + F PV AV+ L DY +IIK PMDL+TI+K L++ Y ++ ED +F NCY YN DI +A+ L+ +F + S+ PQ QV K E + + T Q + ++KS EK+ KQ
Sbjct: 39 VLKDL----WKHSFSWPFQRPVDAVKL-QLPDYYTIIKNPMDLNTIKKRLENKYYAKASECIEDFNTMFSNCYLYNKPGDDIVLMAQALEKLFMQKLSQM-----PQEEQVVGVK---ERIKKGTQQNIAVSSAKEKS----SPSATEKVFKQ 174
BLAST of Bromodomain containing 2 vs. Ensembl Celegans
Match: bet-2 (BET (Two bromodomains) family protein [Source:UniProtKB/TrEMBL;Acc:A0A0K3ASR2]) HSP 1 Score: 101.679 bits (252), Expect = 1.291e-21 Identity = 51/119 (42.86%), Postives = 71/119 (59.66%), Query Frame = 2
Query: 173 SGKPRPANISTNRLQFIKKKILPQLMRHKYSFPFLHPVDHAALNIPDYPKIIHYPMDFTTVKNRLIKKFYYNADECITDIRLVFQNCYIFNPPEIDLISMTLTLENIFNSKLDKLPSQE 529
+GKP TN L F+ ++ ++HK+S+PF PVD L IP+Y I++ PMD T++ RL +Y+ A++ I DI VF NCY FNPPE D+ M TLE S+L +LP E
Sbjct: 277 AGKP---TRHTNCLDFVLFTVVKDALKHKHSWPFQLPVDAIKLEIPEYHNIVNTPMDLRTIEKRLRNLYYWCAEDAIKDINQVFINCYSFNPPEYDVYKMAKTLEKQVLSQLTQLPRSE 392 HSP 2 Score: 67.0106 bits (162), Expect = 5.536e-11 Identity = 37/106 (34.91%), Postives = 55/106 (51.89%), Query Frame = 2
Query: 830 KLSEELKMCSNILRDISSNRYRHLNDMFMEPVAVRFPNLSDYSSIIKKPMDLSTIRKNLDDGSYKTKNDFSEDVKLIFDNCYDYNGKDSDISKLAKDLQNIFDELF 1147
K+ E K CS +L +I S + + +F PV + DY +I PMDL TI+K LD Y +F D+ L+ DNC YN K S A +L++ F++ +
Sbjct: 552 KIPEWQKFCSKLLNEIHSVKNKGFAQVFYLPVDPIKLKIYDYLEVITNPMDLQTIKKKLDFKQYAEPEEFVHDINLMVDNCCKYNPKGSPAHSNALELRSFFEQRW 657 HSP 3 Score: 53.9138 bits (128), Expect = 6.993e-7 Identity = 34/105 (32.38%), Postives = 47/105 (44.76%), Query Frame = 2
Query: 206 NRLQFIKKKILPQLMRHKYSFPFLHPVDHAALNIPDYPKIIHYPMDFTTVKNRLIKKFYYNADECITDIRLVFQNCYIFNPPEIDLISMTLTLENIFNSKLDKLP 520
N + +K K Q+ F PVD L I DY ++I PMD T+K +L K Y +E + DI L+ NC +NP S L L + F + P
Sbjct: 565 NEIHSVKNKGFAQV--------FYLPVDPIKLKIYDYLEVITNPMDLQTIKKKLDFKQYAEPEEFVHDINLMVDNCCKYNPKGSPAHSNALELRSFFEQRWKLFP 661 HSP 4 Score: 50.0618 bits (118), Expect = 8.918e-6 Identity = 26/72 (36.11%), Postives = 39/72 (54.17%), Query Frame = 2
Query: 911 FMEPVAVRFPNLSDYSSIIKKPMDLSTIRKNLDDGSYKTKNDFSEDVKLIFDNCYDYNGKDSDISKLAKDLQ 1126
F PV + +Y +I+ PMDL TI K L + Y D +D+ +F NCY +N + D+ K+AK L+
Sbjct: 307 FQLPVDAIKLEIPEYHNIVNTPMDLRTIEKRLRNLYYWCAEDAIKDINQVFINCYSFNPPEYDVYKMAKTLE 378
BLAST of Bromodomain containing 2 vs. Ensembl Celegans
Match: bet-2 (BET (Two bromodomains) family protein [Source:UniProtKB/TrEMBL;Acc:A0A0K3ASR2]) HSP 1 Score: 101.679 bits (252), Expect = 1.291e-21 Identity = 51/119 (42.86%), Postives = 71/119 (59.66%), Query Frame = 2
Query: 173 SGKPRPANISTNRLQFIKKKILPQLMRHKYSFPFLHPVDHAALNIPDYPKIIHYPMDFTTVKNRLIKKFYYNADECITDIRLVFQNCYIFNPPEIDLISMTLTLENIFNSKLDKLPSQE 529
+GKP TN L F+ ++ ++HK+S+PF PVD L IP+Y I++ PMD T++ RL +Y+ A++ I DI VF NCY FNPPE D+ M TLE S+L +LP E
Sbjct: 277 AGKP---TRHTNCLDFVLFTVVKDALKHKHSWPFQLPVDAIKLEIPEYHNIVNTPMDLRTIEKRLRNLYYWCAEDAIKDINQVFINCYSFNPPEYDVYKMAKTLEKQVLSQLTQLPRSE 392 HSP 2 Score: 67.0106 bits (162), Expect = 5.536e-11 Identity = 37/106 (34.91%), Postives = 55/106 (51.89%), Query Frame = 2
Query: 830 KLSEELKMCSNILRDISSNRYRHLNDMFMEPVAVRFPNLSDYSSIIKKPMDLSTIRKNLDDGSYKTKNDFSEDVKLIFDNCYDYNGKDSDISKLAKDLQNIFDELF 1147
K+ E K CS +L +I S + + +F PV + DY +I PMDL TI+K LD Y +F D+ L+ DNC YN K S A +L++ F++ +
Sbjct: 552 KIPEWQKFCSKLLNEIHSVKNKGFAQVFYLPVDPIKLKIYDYLEVITNPMDLQTIKKKLDFKQYAEPEEFVHDINLMVDNCCKYNPKGSPAHSNALELRSFFEQRW 657 HSP 3 Score: 53.9138 bits (128), Expect = 6.993e-7 Identity = 34/105 (32.38%), Postives = 47/105 (44.76%), Query Frame = 2
Query: 206 NRLQFIKKKILPQLMRHKYSFPFLHPVDHAALNIPDYPKIIHYPMDFTTVKNRLIKKFYYNADECITDIRLVFQNCYIFNPPEIDLISMTLTLENIFNSKLDKLP 520
N + +K K Q+ F PVD L I DY ++I PMD T+K +L K Y +E + DI L+ NC +NP S L L + F + P
Sbjct: 565 NEIHSVKNKGFAQV--------FYLPVDPIKLKIYDYLEVITNPMDLQTIKKKLDFKQYAEPEEFVHDINLMVDNCCKYNPKGSPAHSNALELRSFFEQRWKLFP 661 HSP 4 Score: 50.0618 bits (118), Expect = 8.918e-6 Identity = 26/72 (36.11%), Postives = 39/72 (54.17%), Query Frame = 2
Query: 911 FMEPVAVRFPNLSDYSSIIKKPMDLSTIRKNLDDGSYKTKNDFSEDVKLIFDNCYDYNGKDSDISKLAKDLQ 1126
F PV + +Y +I+ PMDL TI K L + Y D +D+ +F NCY +N + D+ K+AK L+
Sbjct: 307 FQLPVDAIKLEIPEYHNIVNTPMDLRTIEKRLRNLYYWCAEDAIKDINQVFINCYSFNPPEYDVYKMAKTLE 378
BLAST of Bromodomain containing 2 vs. Ensembl Celegans
Match: bet-2 (BET (Two bromodomains) family protein [Source:UniProtKB/TrEMBL;Acc:A0A0K3ASR2]) HSP 1 Score: 101.293 bits (251), Expect = 1.748e-21 Identity = 51/119 (42.86%), Postives = 71/119 (59.66%), Query Frame = 2
Query: 173 SGKPRPANISTNRLQFIKKKILPQLMRHKYSFPFLHPVDHAALNIPDYPKIIHYPMDFTTVKNRLIKKFYYNADECITDIRLVFQNCYIFNPPEIDLISMTLTLENIFNSKLDKLPSQE 529
+GKP TN L F+ ++ ++HK+S+PF PVD L IP+Y I++ PMD T++ RL +Y+ A++ I DI VF NCY FNPPE D+ M TLE S+L +LP E
Sbjct: 277 AGKP---TRHTNCLDFVLFTVVKDALKHKHSWPFQLPVDAIKLEIPEYHNIVNTPMDLRTIEKRLRNLYYWCAEDAIKDINQVFINCYSFNPPEYDVYKMAKTLEKQVLSQLTQLPRSE 392 HSP 2 Score: 67.3958 bits (163), Expect = 5.213e-11 Identity = 37/106 (34.91%), Postives = 55/106 (51.89%), Query Frame = 2
Query: 830 KLSEELKMCSNILRDISSNRYRHLNDMFMEPVAVRFPNLSDYSSIIKKPMDLSTIRKNLDDGSYKTKNDFSEDVKLIFDNCYDYNGKDSDISKLAKDLQNIFDELF 1147
K+ E K CS +L +I S + + +F PV + DY +I PMDL TI+K LD Y +F D+ L+ DNC YN K S A +L++ F++ +
Sbjct: 552 KIPEWQKFCSKLLNEIHSVKNKGFAQVFYLPVDPIKLKIYDYLEVITNPMDLQTIKKKLDFKQYAEPEEFVHDINLMVDNCCKYNPKGSPAHSNALELRSFFEQRW 657 HSP 3 Score: 53.5286 bits (127), Expect = 8.065e-7 Identity = 34/105 (32.38%), Postives = 47/105 (44.76%), Query Frame = 2
Query: 206 NRLQFIKKKILPQLMRHKYSFPFLHPVDHAALNIPDYPKIIHYPMDFTTVKNRLIKKFYYNADECITDIRLVFQNCYIFNPPEIDLISMTLTLENIFNSKLDKLP 520
N + +K K Q+ F PVD L I DY ++I PMD T+K +L K Y +E + DI L+ NC +NP S L L + F + P
Sbjct: 565 NEIHSVKNKGFAQV--------FYLPVDPIKLKIYDYLEVITNPMDLQTIKKKLDFKQYAEPEEFVHDINLMVDNCCKYNPKGSPAHSNALELRSFFEQRWKLFP 661 HSP 4 Score: 50.447 bits (119), Expect = 8.442e-6 Identity = 27/73 (36.99%), Postives = 42/73 (57.53%), Query Frame = 2
Query: 911 FMEPV-AVRFPNLSDYSSIIKKPMDLSTIRKNLDDGSYKTKNDFSEDVKLIFDNCYDYNGKDSDISKLAKDLQ 1126
F PV A++ + +Y +I+ PMDL TI K L + Y D +D+ +F NCY +N + D+ K+AK L+
Sbjct: 307 FQLPVDAIKL-EIPEYHNIVNTPMDLRTIEKRLRNLYYWCAEDAIKDINQVFINCYSFNPPEYDVYKMAKTLE 378
BLAST of Bromodomain containing 2 vs. Ensembl Celegans
Match: bet-1 (Bromodomain-containing protein bet-1 [Source:UniProtKB/Swiss-Prot;Acc:Q95Y80]) HSP 1 Score: 100.138 bits (248), Expect = 3.365e-21 Identity = 48/118 (40.68%), Postives = 66/118 (55.93%), Query Frame = 2
Query: 176 GKPRPANISTNRLQFIKKKILPQLMRHKYSFPFLHPVDHAALNIPDYPKIIHYPMDFTTVKNRLIKKFYYNADECITDIRLVFQNCYIFNPPEIDLISMTLTLENIFNSKLDKLPSQE 529
GKP TN+L +I +L + +HK+ +PF PVD AL IP Y + + PMD T++NRL +Y A ECI DI VFQNCY FN E D+ M + + L++ P +E
Sbjct: 35 GKP---TRHTNKLDYIMTTVLKEAGKHKHVWPFQKPVDAVALCIPLYHERVARPMDLKTIENRLKSTYYTCAQECIDDIETVFQNCYTFNGKEDDVTIMAQNVHEVIKKSLEQAPREE 149 HSP 2 Score: 83.1889 bits (204), Expect = 6.030e-16 Identity = 48/147 (32.65%), Postives = 74/147 (50.34%), Query Frame = 2
Query: 716 AKSKAKKRKVESCYDLSPTPSPSISLKNE-SLDEIPIKPKLSEELKMCSNILRDISSNRYRHLNDMFMEPVAVRFPNLSDYSSIIKKPMDLSTIRKNLDDGSYKTKNDFSEDVKLIFDNCYDYNGKDSDISKLAKDLQNIFDELFSK 1153
A K KRK ES D P P + K E ++ + + L +K C +L D S+ +Y+ F EPV L DY IIK+PMDL +++ ++ G+YK +DF DV+L+ NC+ YN + Q +FD +++
Sbjct: 222 AGKKTGKRKAESEDDEKPEP---LRAKREVAVVKKEVHQPLLPSMKPCLKLLNDFSTKKYQEFAWPFNEPVDAEQLGLHDYHKIIKEPMDLKSMKAKMESGAYKEPSDFEHDVRLMLRNCFLYNPVGDPVHSFGLRFQEVFDRRWAE 365 HSP 3 Score: 65.4698 bits (158), Expect = 1.790e-10 Identity = 27/88 (30.68%), Postives = 49/88 (55.68%), Query Frame = 2
Query: 254 HKYSFPFLHPVDHAALNIPDYPKIIHYPMDFTTVKNRLIKKFYYNADECITDIRLVFQNCYIFNPPEIDLISMTLTLENIFNSKLDKL 517
++++PF PVD L + DY KII PMD ++K ++ Y + D+RL+ +NC+++NP + S L + +F+ + +L
Sbjct: 279 QEFAWPFNEPVDAEQLGLHDYHKIIKEPMDLKSMKAKMESGAYKEPSDFEHDVRLMLRNCFLYNPVGDPVHSFGLRFQEVFDRRWAEL 366 HSP 4 Score: 52.373 bits (124), Expect = 1.739e-6 Identity = 23/85 (27.06%), Postives = 46/85 (54.12%), Query Frame = 2
Query: 881 SNRYRHLNDMFMEPVAVRFPNLSDYSSIIKKPMDLSTIRKNLDDGSYKTKNDFSEDVKLIFDNCYDYNGKDSDISKLAKDLQNIF 1135
+ +++H+ F +PV + Y + +PMDL TI L Y + +D++ +F NCY +NGK+ D++ +A+++ +
Sbjct: 55 AGKHKHVWP-FQKPVDAVALCIPLYHERVARPMDLKTIENRLKSTYYTCAQECIDDIETVFQNCYTFNGKEDDVTIMAQNVHEVI 138 HSP 5 Score: 51.9878 bits (123), Expect = 2.151e-6 Identity = 29/71 (40.85%), Postives = 45/71 (63.38%), Query Frame = 2
Query: 1700 MSYDDKRKLSMDINQLPGDKLGRIVQIIQEREPT------LRDSNPDEIEIDFEVLHPVTLRELQKFVQSV 1894
++Y++KR LS IN LP ++L I+ IIQ RE + L DS E+E+DFE L + LRE+ F++++
Sbjct: 526 LTYEEKRNLSNLINNLPNNQLNTIISIIQRRERSALMQQQLDDS---EVELDFESLGDMCLREMGAFIKTI 593
BLAST of Bromodomain containing 2 vs. Ensembl Celegans
Match: bet-1 (Bromodomain-containing protein bet-1 [Source:UniProtKB/Swiss-Prot;Acc:Q95Y80]) HSP 1 Score: 99.3673 bits (246), Expect = 5.083e-21 Identity = 48/118 (40.68%), Postives = 66/118 (55.93%), Query Frame = 2
Query: 176 GKPRPANISTNRLQFIKKKILPQLMRHKYSFPFLHPVDHAALNIPDYPKIIHYPMDFTTVKNRLIKKFYYNADECITDIRLVFQNCYIFNPPEIDLISMTLTLENIFNSKLDKLPSQE 529
GKP TN+L +I +L + +HK+ +PF PVD AL IP Y + + PMD T++NRL +Y A ECI DI VFQNCY FN E D+ M + + L++ P +E
Sbjct: 35 GKP---TRHTNKLDYIMTTVLKEAGKHKHVWPFQKPVDAVALCIPLYHERVARPMDLKTIENRLKSTYYTCAQECIDDIETVFQNCYTFNGKEDDVTIMAQNVHEVIKKSLEQAPREE 149 HSP 2 Score: 82.8037 bits (203), Expect = 6.822e-16 Identity = 48/147 (32.65%), Postives = 74/147 (50.34%), Query Frame = 2
Query: 716 AKSKAKKRKVESCYDLSPTPSPSISLKNE-SLDEIPIKPKLSEELKMCSNILRDISSNRYRHLNDMFMEPVAVRFPNLSDYSSIIKKPMDLSTIRKNLDDGSYKTKNDFSEDVKLIFDNCYDYNGKDSDISKLAKDLQNIFDELFSK 1153
A K KRK ES D P P + K E ++ + + L +K C +L D S+ +Y+ F EPV L DY IIK+PMDL +++ ++ G+YK +DF DV+L+ NC+ YN + Q +FD +++
Sbjct: 222 AGKKTGKRKAESEDDEKPEP---LRAKREVAVVKKEVHQPLLPSMKPCLKLLNDFSTKKYQEFAWPFNEPVDAEQLGLHDYHKIIKEPMDLKSMKAKMESGAYKEPSDFEHDVRLMLRNCFLYNPVGDPVHSFGLRFQEVFDRRWAE 365 HSP 3 Score: 64.3142 bits (155), Expect = 3.277e-10 Identity = 27/88 (30.68%), Postives = 49/88 (55.68%), Query Frame = 2
Query: 254 HKYSFPFLHPVDHAALNIPDYPKIIHYPMDFTTVKNRLIKKFYYNADECITDIRLVFQNCYIFNPPEIDLISMTLTLENIFNSKLDKL 517
++++PF PVD L + DY KII PMD ++K ++ Y + D+RL+ +NC+++NP + S L + +F+ + +L
Sbjct: 279 QEFAWPFNEPVDAEQLGLHDYHKIIKEPMDLKSMKAKMESGAYKEPSDFEHDVRLMLRNCFLYNPVGDPVHSFGLRFQEVFDRRWAEL 366 HSP 4 Score: 52.7582 bits (125), Expect = 1.413e-6 Identity = 23/85 (27.06%), Postives = 46/85 (54.12%), Query Frame = 2
Query: 881 SNRYRHLNDMFMEPVAVRFPNLSDYSSIIKKPMDLSTIRKNLDDGSYKTKNDFSEDVKLIFDNCYDYNGKDSDISKLAKDLQNIF 1135
+ +++H+ F +PV + Y + +PMDL TI L Y + +D++ +F NCY +NGK+ D++ +A+++ +
Sbjct: 55 AGKHKHVWP-FQKPVDAVALCIPLYHERVARPMDLKTIENRLKSTYYTCAQECIDDIETVFQNCYTFNGKEDDVTIMAQNVHEVI 138 HSP 5 Score: 52.373 bits (124), Expect = 1.841e-6 Identity = 29/71 (40.85%), Postives = 45/71 (63.38%), Query Frame = 2
Query: 1700 MSYDDKRKLSMDINQLPGDKLGRIVQIIQEREPT------LRDSNPDEIEIDFEVLHPVTLRELQKFVQSV 1894
++Y++KR LS IN LP ++L I+ IIQ RE + L DS E+E+DFE L + LRE+ F++++
Sbjct: 526 LTYEEKRNLSNLINNLPNNQLNTIISIIQRRERSALMQQQLDDS---EVELDFESLGDMCLREMGAFIKTI 593
BLAST of Bromodomain containing 2 vs. Ensembl Fly
Match: fs(1)h (gene:FBgn0004656 transcript:FBtr0333307) HSP 1 Score: 118.242 bits (295), Expect = 1.976e-26 Identity = 52/72 (72.22%), Postives = 62/72 (86.11%), Query Frame = 2
Query: 1691 CKPMSYDDKRKLSMDINQLPGDKLGRIVQIIQEREPTLRDSNPDEIEIDFEVLHPVTLRELQKFVQSVLSRQ 1906
KPMSYD+KR+LS+DIN+LPGDKLGR+V IIQ REP+LRDSNPDEIEIDFE L P TLREL+ +V S L ++
Sbjct: 949 AKPMSYDEKRQLSLDINKLPGDKLGRVVHIIQNREPSLRDSNPDEIEIDFETLKPSTLRELESYVASCLRKK 1020 HSP 2 Score: 116.316 bits (290), Expect = 7.391e-26 Identity = 49/115 (42.61%), Postives = 74/115 (64.35%), Query Frame = 2
Query: 185 RPANISTNRLQFIKKKILPQLMRHKYSFPFLHPVDHAALNIPDYPKIIHYPMDFTTVKNRLIKKFYYNADECITDIRLVFQNCYIFNPPEIDLISMTLTLENIFNSKLDKLPSQE 529
RP +TN+LQ++ K ++ + +H +S+PF PVD LN+PDY KII PMD T+K RL +Y++A E I D +F NCY++N P D++ M TLE +F K++ +P +E
Sbjct: 31 RPGR-NTNQLQYLIKTVMKVIWKHHFSWPFQQPVDAKKLNLPDYHKIIKQPMDMGTIKKRLENNYYWSAKETIQDFNTMFNNCYVYNKPGEDVVVMAQTLEKVFLQKIESMPKEE 144 HSP 3 Score: 100.138 bits (248), Expect = 6.258e-21 Identity = 44/109 (40.37%), Postives = 69/109 (63.30%), Query Frame = 2
Query: 824 KPKLSEELKMCSNILRDISSNRYRHLNDMFMEPVAVRFPNLSDYSSIIKKPMDLSTIRKNLDDGSYKTKNDFSEDVKLIFDNCYDYNGKDSDISKLAKDLQNIFDELFS 1150
K KLS+ LK C+ IL+++ S ++ F +PV L DY IIKKPMDL T+++ +D+ YK+ +F+ DV+LIF NCY YN D D+ + + LQ++F+ ++
Sbjct: 474 KEKLSDALKSCNEILKELFSKKHSGYAWPFYKPVDAEMLGLHDYHDIIKKPMDLGTVKRKMDNREYKSAPEFAADVRLIFTNCYKYNPPDHDVVAMGRKLQDVFEMRYA 582 HSP 4 Score: 87.4261 bits (215), Expect = 5.960e-17 Identity = 39/100 (39.00%), Postives = 60/100 (60.00%), Query Frame = 2
Query: 230 KILPQLMRHK---YSFPFLHPVDHAALNIPDYPKIIHYPMDFTTVKNRLIKKFYYNADECITDIRLVFQNCYIFNPPEIDLISMTLTLENIFNSKLDKLP 520
+IL +L K Y++PF PVD L + DY II PMD TVK ++ + Y +A E D+RL+F NCY +NPP+ D+++M L+++F + +P
Sbjct: 486 EILKELFSKKHSGYAWPFYKPVDAEMLGLHDYHDIIKKPMDLGTVKRKMDNREYKSAPEFAADVRLIFTNCYKYNPPDHDVVAMGRKLQDVFEMRYANIP 585 HSP 5 Score: 68.5514 bits (166), Expect = 2.752e-11 Identity = 30/81 (37.04%), Postives = 48/81 (59.26%), Query Frame = 2
Query: 893 RHLNDMFMEPVAVRFPNLSDYSSIIKKPMDLSTIRKNLDDGSYKTKNDFSEDVKLIFDNCYDYNGKDSDISKLAKDLQNIF 1135
H + F +PV + NL DY IIK+PMD+ TI+K L++ Y + + +D +F+NCY YN D+ +A+ L+ +F
Sbjct: 53 HHFSWPFQQPVDAKKLNLPDYHKIIKQPMDMGTIKKRLENNYYWSAKETIQDFNTMFNNCYVYNKPGEDVVVMAQTLEKVF 133
BLAST of Bromodomain containing 2 vs. Ensembl Fly
Match: fs(1)h (gene:FBgn0004656 transcript:FBtr0071119) HSP 1 Score: 118.242 bits (295), Expect = 2.095e-26 Identity = 52/72 (72.22%), Postives = 62/72 (86.11%), Query Frame = 2
Query: 1691 CKPMSYDDKRKLSMDINQLPGDKLGRIVQIIQEREPTLRDSNPDEIEIDFEVLHPVTLRELQKFVQSVLSRQ 1906
KPMSYD+KR+LS+DIN+LPGDKLGR+V IIQ REP+LRDSNPDEIEIDFE L P TLREL+ +V S L ++
Sbjct: 949 AKPMSYDEKRQLSLDINKLPGDKLGRVVHIIQNREPSLRDSNPDEIEIDFETLKPSTLRELESYVASCLRKK 1020 HSP 2 Score: 116.316 bits (290), Expect = 7.382e-26 Identity = 49/115 (42.61%), Postives = 74/115 (64.35%), Query Frame = 2
Query: 185 RPANISTNRLQFIKKKILPQLMRHKYSFPFLHPVDHAALNIPDYPKIIHYPMDFTTVKNRLIKKFYYNADECITDIRLVFQNCYIFNPPEIDLISMTLTLENIFNSKLDKLPSQE 529
RP +TN+LQ++ K ++ + +H +S+PF PVD LN+PDY KII PMD T+K RL +Y++A E I D +F NCY++N P D++ M TLE +F K++ +P +E
Sbjct: 31 RPGR-NTNQLQYLIKTVMKVIWKHHFSWPFQQPVDAKKLNLPDYHKIIKQPMDMGTIKKRLENNYYWSAKETIQDFNTMFNNCYVYNKPGEDVVVMAQTLEKVFLQKIESMPKEE 144 HSP 3 Score: 100.138 bits (248), Expect = 6.690e-21 Identity = 44/109 (40.37%), Postives = 69/109 (63.30%), Query Frame = 2
Query: 824 KPKLSEELKMCSNILRDISSNRYRHLNDMFMEPVAVRFPNLSDYSSIIKKPMDLSTIRKNLDDGSYKTKNDFSEDVKLIFDNCYDYNGKDSDISKLAKDLQNIFDELFS 1150
K KLS+ LK C+ IL+++ S ++ F +PV L DY IIKKPMDL T+++ +D+ YK+ +F+ DV+LIF NCY YN D D+ + + LQ++F+ ++
Sbjct: 474 KEKLSDALKSCNEILKELFSKKHSGYAWPFYKPVDAEMLGLHDYHDIIKKPMDLGTVKRKMDNREYKSAPEFAADVRLIFTNCYKYNPPDHDVVAMGRKLQDVFEMRYA 582 HSP 4 Score: 87.4261 bits (215), Expect = 5.905e-17 Identity = 39/100 (39.00%), Postives = 60/100 (60.00%), Query Frame = 2
Query: 230 KILPQLMRHK---YSFPFLHPVDHAALNIPDYPKIIHYPMDFTTVKNRLIKKFYYNADECITDIRLVFQNCYIFNPPEIDLISMTLTLENIFNSKLDKLP 520
+IL +L K Y++PF PVD L + DY II PMD TVK ++ + Y +A E D+RL+F NCY +NPP+ D+++M L+++F + +P
Sbjct: 486 EILKELFSKKHSGYAWPFYKPVDAEMLGLHDYHDIIKKPMDLGTVKRKMDNREYKSAPEFAADVRLIFTNCYKYNPPDHDVVAMGRKLQDVFEMRYANIP 585 HSP 5 Score: 68.5514 bits (166), Expect = 2.918e-11 Identity = 30/81 (37.04%), Postives = 48/81 (59.26%), Query Frame = 2
Query: 893 RHLNDMFMEPVAVRFPNLSDYSSIIKKPMDLSTIRKNLDDGSYKTKNDFSEDVKLIFDNCYDYNGKDSDISKLAKDLQNIF 1135
H + F +PV + NL DY IIK+PMD+ TI+K L++ Y + + +D +F+NCY YN D+ +A+ L+ +F
Sbjct: 53 HHFSWPFQQPVDAKKLNLPDYHKIIKQPMDMGTIKKRLENNYYWSAKETIQDFNTMFNNCYVYNKPGEDVVVMAQTLEKVF 133
BLAST of Bromodomain containing 2 vs. Ensembl Fly
Match: fs(1)h (gene:FBgn0004656 transcript:FBtr0333308) HSP 1 Score: 117.087 bits (292), Expect = 2.727e-26 Identity = 52/72 (72.22%), Postives = 62/72 (86.11%), Query Frame = 2
Query: 1691 CKPMSYDDKRKLSMDINQLPGDKLGRIVQIIQEREPTLRDSNPDEIEIDFEVLHPVTLRELQKFVQSVLSRQ 1906
KPMSYD+KR+LS+DIN+LPGDKLGR+V IIQ REP+LRDSNPDEIEIDFE L P TLREL+ +V S L ++
Sbjct: 944 AKPMSYDEKRQLSLDINKLPGDKLGRVVHIIQNREPSLRDSNPDEIEIDFETLKPSTLRELESYVASCLRKK 1015 HSP 2 Score: 115.546 bits (288), Expect = 1.037e-25 Identity = 49/115 (42.61%), Postives = 74/115 (64.35%), Query Frame = 2
Query: 185 RPANISTNRLQFIKKKILPQLMRHKYSFPFLHPVDHAALNIPDYPKIIHYPMDFTTVKNRLIKKFYYNADECITDIRLVFQNCYIFNPPEIDLISMTLTLENIFNSKLDKLPSQE 529
RP +TN+LQ++ K ++ + +H +S+PF PVD LN+PDY KII PMD T+K RL +Y++A E I D +F NCY++N P D++ M TLE +F K++ +P +E
Sbjct: 31 RPGR-NTNQLQYLIKTVMKVIWKHHFSWPFQQPVDAKKLNLPDYHKIIKQPMDMGTIKKRLENNYYWSAKETIQDFNTMFNNCYVYNKPGEDVVVMAQTLEKVFLQKIESMPKEE 144 HSP 3 Score: 100.523 bits (249), Expect = 4.382e-21 Identity = 44/109 (40.37%), Postives = 69/109 (63.30%), Query Frame = 2
Query: 824 KPKLSEELKMCSNILRDISSNRYRHLNDMFMEPVAVRFPNLSDYSSIIKKPMDLSTIRKNLDDGSYKTKNDFSEDVKLIFDNCYDYNGKDSDISKLAKDLQNIFDELFS 1150
K KLS+ LK C+ IL+++ S ++ F +PV L DY IIKKPMDL T+++ +D+ YK+ +F+ DV+LIF NCY YN D D+ + + LQ++F+ ++
Sbjct: 469 KEKLSDALKSCNEILKELFSKKHSGYAWPFYKPVDAEMLGLHDYHDIIKKPMDLGTVKRKMDNREYKSAPEFAADVRLIFTNCYKYNPPDHDVVAMGRKLQDVFEMRYA 577 HSP 4 Score: 86.6557 bits (213), Expect = 7.365e-17 Identity = 39/102 (38.24%), Postives = 61/102 (59.80%), Query Frame = 2
Query: 230 KILPQLMRHK---YSFPFLHPVDHAALNIPDYPKIIHYPMDFTTVKNRLIKKFYYNADECITDIRLVFQNCYIFNPPEIDLISMTLTLENIFNSKLDKLPSQ 526
+IL +L K Y++PF PVD L + DY II PMD TVK ++ + Y +A E D+RL+F NCY +NPP+ D+++M L+++F + +P +
Sbjct: 481 EILKELFSKKHSGYAWPFYKPVDAEMLGLHDYHDIIKKPMDLGTVKRKMDNREYKSAPEFAADVRLIFTNCYKYNPPDHDVVAMGRKLQDVFEMRYANIPDE 582 HSP 5 Score: 68.9366 bits (167), Expect = 1.892e-11 Identity = 30/81 (37.04%), Postives = 48/81 (59.26%), Query Frame = 2
Query: 893 RHLNDMFMEPVAVRFPNLSDYSSIIKKPMDLSTIRKNLDDGSYKTKNDFSEDVKLIFDNCYDYNGKDSDISKLAKDLQNIF 1135
H + F +PV + NL DY IIK+PMD+ TI+K L++ Y + + +D +F+NCY YN D+ +A+ L+ +F
Sbjct: 53 HHFSWPFQQPVDAKKLNLPDYHKIIKQPMDMGTIKKRLENNYYWSAKETIQDFNTMFNNCYVYNKPGEDVVVMAQTLEKVF 133
BLAST of Bromodomain containing 2 vs. Ensembl Fly
Match: fs(1)h (gene:FBgn0004656 transcript:FBtr0333309) HSP 1 Score: 117.087 bits (292), Expect = 2.771e-26 Identity = 52/72 (72.22%), Postives = 62/72 (86.11%), Query Frame = 2
Query: 1691 CKPMSYDDKRKLSMDINQLPGDKLGRIVQIIQEREPTLRDSNPDEIEIDFEVLHPVTLRELQKFVQSVLSRQ 1906
KPMSYD+KR+LS+DIN+LPGDKLGR+V IIQ REP+LRDSNPDEIEIDFE L P TLREL+ +V S L ++
Sbjct: 954 AKPMSYDEKRQLSLDINKLPGDKLGRVVHIIQNREPSLRDSNPDEIEIDFETLKPSTLRELESYVASCLRKK 1025 HSP 2 Score: 115.546 bits (288), Expect = 9.110e-26 Identity = 49/115 (42.61%), Postives = 74/115 (64.35%), Query Frame = 2
Query: 185 RPANISTNRLQFIKKKILPQLMRHKYSFPFLHPVDHAALNIPDYPKIIHYPMDFTTVKNRLIKKFYYNADECITDIRLVFQNCYIFNPPEIDLISMTLTLENIFNSKLDKLPSQE 529
RP +TN+LQ++ K ++ + +H +S+PF PVD LN+PDY KII PMD T+K RL +Y++A E I D +F NCY++N P D++ M TLE +F K++ +P +E
Sbjct: 31 RPGR-NTNQLQYLIKTVMKVIWKHHFSWPFQQPVDAKKLNLPDYHKIIKQPMDMGTIKKRLENNYYWSAKETIQDFNTMFNNCYVYNKPGEDVVVMAQTLEKVFLQKIESMPKEE 144 HSP 3 Score: 100.523 bits (249), Expect = 4.116e-21 Identity = 44/109 (40.37%), Postives = 69/109 (63.30%), Query Frame = 2
Query: 824 KPKLSEELKMCSNILRDISSNRYRHLNDMFMEPVAVRFPNLSDYSSIIKKPMDLSTIRKNLDDGSYKTKNDFSEDVKLIFDNCYDYNGKDSDISKLAKDLQNIFDELFS 1150
K KLS+ LK C+ IL+++ S ++ F +PV L DY IIKKPMDL T+++ +D+ YK+ +F+ DV+LIF NCY YN D D+ + + LQ++F+ ++
Sbjct: 479 KEKLSDALKSCNEILKELFSKKHSGYAWPFYKPVDAEMLGLHDYHDIIKKPMDLGTVKRKMDNREYKSAPEFAADVRLIFTNCYKYNPPDHDVVAMGRKLQDVFEMRYA 587 HSP 4 Score: 86.6557 bits (213), Expect = 6.910e-17 Identity = 39/102 (38.24%), Postives = 61/102 (59.80%), Query Frame = 2
Query: 230 KILPQLMRHK---YSFPFLHPVDHAALNIPDYPKIIHYPMDFTTVKNRLIKKFYYNADECITDIRLVFQNCYIFNPPEIDLISMTLTLENIFNSKLDKLPSQ 526
+IL +L K Y++PF PVD L + DY II PMD TVK ++ + Y +A E D+RL+F NCY +NPP+ D+++M L+++F + +P +
Sbjct: 491 EILKELFSKKHSGYAWPFYKPVDAEMLGLHDYHDIIKKPMDLGTVKRKMDNREYKSAPEFAADVRLIFTNCYKYNPPDHDVVAMGRKLQDVFEMRYANIPDE 592 HSP 5 Score: 68.9366 bits (167), Expect = 1.850e-11 Identity = 30/81 (37.04%), Postives = 48/81 (59.26%), Query Frame = 2
Query: 893 RHLNDMFMEPVAVRFPNLSDYSSIIKKPMDLSTIRKNLDDGSYKTKNDFSEDVKLIFDNCYDYNGKDSDISKLAKDLQNIF 1135
H + F +PV + NL DY IIK+PMD+ TI+K L++ Y + + +D +F+NCY YN D+ +A+ L+ +F
Sbjct: 53 HHFSWPFQQPVDAKKLNLPDYHKIIKQPMDMGTIKKRLENNYYWSAKETIQDFNTMFNNCYVYNKPGEDVVVMAQTLEKVF 133
BLAST of Bromodomain containing 2 vs. Ensembl Fly
Match: fs(1)h (gene:FBgn0004656 transcript:FBtr0071122) HSP 1 Score: 117.087 bits (292), Expect = 2.907e-26 Identity = 52/72 (72.22%), Postives = 62/72 (86.11%), Query Frame = 2
Query: 1691 CKPMSYDDKRKLSMDINQLPGDKLGRIVQIIQEREPTLRDSNPDEIEIDFEVLHPVTLRELQKFVQSVLSRQ 1906
KPMSYD+KR+LS+DIN+LPGDKLGR+V IIQ REP+LRDSNPDEIEIDFE L P TLREL+ +V S L ++
Sbjct: 949 AKPMSYDEKRQLSLDINKLPGDKLGRVVHIIQNREPSLRDSNPDEIEIDFETLKPSTLRELESYVASCLRKK 1020 HSP 2 Score: 115.546 bits (288), Expect = 1.050e-25 Identity = 49/115 (42.61%), Postives = 74/115 (64.35%), Query Frame = 2
Query: 185 RPANISTNRLQFIKKKILPQLMRHKYSFPFLHPVDHAALNIPDYPKIIHYPMDFTTVKNRLIKKFYYNADECITDIRLVFQNCYIFNPPEIDLISMTLTLENIFNSKLDKLPSQE 529
RP +TN+LQ++ K ++ + +H +S+PF PVD LN+PDY KII PMD T+K RL +Y++A E I D +F NCY++N P D++ M TLE +F K++ +P +E
Sbjct: 31 RPGR-NTNQLQYLIKTVMKVIWKHHFSWPFQQPVDAKKLNLPDYHKIIKQPMDMGTIKKRLENNYYWSAKETIQDFNTMFNNCYVYNKPGEDVVVMAQTLEKVFLQKIESMPKEE 144 HSP 3 Score: 100.523 bits (249), Expect = 4.432e-21 Identity = 44/109 (40.37%), Postives = 69/109 (63.30%), Query Frame = 2
Query: 824 KPKLSEELKMCSNILRDISSNRYRHLNDMFMEPVAVRFPNLSDYSSIIKKPMDLSTIRKNLDDGSYKTKNDFSEDVKLIFDNCYDYNGKDSDISKLAKDLQNIFDELFS 1150
K KLS+ LK C+ IL+++ S ++ F +PV L DY IIKKPMDL T+++ +D+ YK+ +F+ DV+LIF NCY YN D D+ + + LQ++F+ ++
Sbjct: 474 KEKLSDALKSCNEILKELFSKKHSGYAWPFYKPVDAEMLGLHDYHDIIKKPMDLGTVKRKMDNREYKSAPEFAADVRLIFTNCYKYNPPDHDVVAMGRKLQDVFEMRYA 582 HSP 4 Score: 86.6557 bits (213), Expect = 7.381e-17 Identity = 39/102 (38.24%), Postives = 61/102 (59.80%), Query Frame = 2
Query: 230 KILPQLMRHK---YSFPFLHPVDHAALNIPDYPKIIHYPMDFTTVKNRLIKKFYYNADECITDIRLVFQNCYIFNPPEIDLISMTLTLENIFNSKLDKLPSQ 526
+IL +L K Y++PF PVD L + DY II PMD TVK ++ + Y +A E D+RL+F NCY +NPP+ D+++M L+++F + +P +
Sbjct: 486 EILKELFSKKHSGYAWPFYKPVDAEMLGLHDYHDIIKKPMDLGTVKRKMDNREYKSAPEFAADVRLIFTNCYKYNPPDHDVVAMGRKLQDVFEMRYANIPDE 587 HSP 5 Score: 68.9366 bits (167), Expect = 2.011e-11 Identity = 30/81 (37.04%), Postives = 48/81 (59.26%), Query Frame = 2
Query: 893 RHLNDMFMEPVAVRFPNLSDYSSIIKKPMDLSTIRKNLDDGSYKTKNDFSEDVKLIFDNCYDYNGKDSDISKLAKDLQNIF 1135
H + F +PV + NL DY IIK+PMD+ TI+K L++ Y + + +D +F+NCY YN D+ +A+ L+ +F
Sbjct: 53 HHFSWPFQQPVDAKKLNLPDYHKIIKQPMDMGTIKKRLENNYYWSAKETIQDFNTMFNNCYVYNKPGEDVVVMAQTLEKVF 133
BLAST of Bromodomain containing 2 vs. Ensembl Zebrafish
Match: brd3b (bromodomain containing 3b [Source:ZFIN;Acc:ZDB-GENE-030131-5316]) HSP 1 Score: 119.013 bits (297), Expect = 7.359e-29 Identity = 51/74 (68.92%), Postives = 65/74 (87.84%), Query Frame = 2
Query: 1685 EDCKPMSYDDKRKLSMDINQLPGDKLGRIVQIIQEREPTLRDSNPDEIEIDFEVLHPVTLRELQKFVQSVLSRQ 1906
E+ PMSYD+KR+LS+DIN+LPG+KLGR+V IIQ REP+LRDSNPDEIEIDFE L P TLREL+++V+S L ++
Sbjct: 145 EESLPMSYDEKRQLSLDINRLPGEKLGRVVHIIQSREPSLRDSNPDEIEIDFETLKPSTLRELERYVKSCLQKK 218
BLAST of Bromodomain containing 2 vs. Ensembl Zebrafish
Match: brd2b (bromodomain containing 2b [Source:ZFIN;Acc:ZDB-GENE-070220-1]) HSP 1 Score: 113.235 bits (282), Expect = 3.121e-27 Identity = 49/110 (44.55%), Postives = 70/110 (63.64%), Query Frame = 2
Query: 200 STNRLQFIKKKILPQLMRHKYSFPFLHPVDHAALNIPDYPKIIHYPMDFTTVKNRLIKKFYYNADECITDIRLVFQNCYIFNPPEIDLISMTLTLENIFNSKLDKLPSQE 529
+TN+LQF+ K ++ L RH +++PF PVD LN+PDY KII PMD T+K RL +Y A EC+ D +F NCYI+N P D++ M +LE +F K+ ++P E
Sbjct: 71 ATNQLQFLHKVLVKALWRHHFAWPFHEPVDATRLNLPDYHKIIKQPMDMGTIKKRLENNYYRGASECLQDFNTMFTNCYIYNKPADDIVLMAQSLEKVFLQKVAQMPQDE 180 HSP 2 Score: 70.0922 bits (170), Expect = 1.481e-12 Identity = 37/110 (33.64%), Postives = 57/110 (51.82%), Query Frame = 2
Query: 893 RHLNDMFMEPVAVRFPNLSDYSSIIKKPMDLSTIRKNLDDGSYKTKNDFSEDVKLIFDNCYDYNGKDSDISKLAKDLQNIFDELFSK----QFNLSKPQPSQVQNSKIKS 1210
H F EPV NL DY IIK+PMD+ TI+K L++ Y+ ++ +D +F NCY YN DI +A+ L+ +F + ++ + L P P N +K+
Sbjct: 89 HHFAWPFHEPVDATRLNLPDYHKIIKQPMDMGTIKKRLENNYYRGASECLQDFNTMFTNCYIYNKPADDIVLMAQSLEKVFLQKVAQMPQDEIELPSPTPRGRGNKSVKA 198
BLAST of Bromodomain containing 2 vs. Ensembl Zebrafish
Match: brd3b (bromodomain containing 3b [Source:ZFIN;Acc:ZDB-GENE-030131-5316]) HSP 1 Score: 116.701 bits (291), Expect = 2.479e-26 Identity = 54/93 (58.06%), Postives = 73/93 (78.49%), Query Frame = 2
Query: 1685 EDCKPMSYDDKRKLSMDINQLPGDKLGRIVQIIQEREPTLRDSNPDEIEIDFEVLHPVTLRELQKFVQSVLSRQXXXXXXXXXXXXXGQAGQI 1963
E+ PMSYD+KR+LS+DIN+LPG+KLGR+V IIQ REP+LRDSNPDEIEIDFE L P TLREL+++V+S L +++ +K+ G A ++
Sbjct: 547 EESLPMSYDEKRQLSLDINRLPGEKLGRVVHIIQSREPSLRDSNPDEIEIDFETLKPSTLRELERYVKSCLQKKQRKPLQKAGSAQGGGASRL 639 HSP 2 Score: 115.931 bits (289), Expect = 5.000e-26 Identity = 50/119 (42.02%), Postives = 75/119 (63.03%), Query Frame = 2
Query: 173 SGKPRPANISTNRLQFIKKKILPQLMRHKYSFPFLHPVDHAALNIPDYPKIIHYPMDFTTVKNRLIKKFYYNADECITDIRLVFQNCYIFNPPEIDLISMTLTLENIFNSKLDKLPSQE 529
SGKP TN+LQ+++ ++ L +H++++PF PVD LN+PDY K+I PMD T+K RL +Y+ A EC+ D +F NCYI+N P D++ M LE IF K+ ++P +E
Sbjct: 25 SGKP---GRKTNQLQYMQNVVVKTLWKHQFAWPFYTPVDAIKLNLPDYHKVIKNPMDMGTIKKRLENNYYWTAGECMQDFNTMFTNCYIYNKPTDDIVLMAQALEKIFLQKVAQMPQEE 140 HSP 3 Score: 97.4413 bits (241), Expect = 2.766e-20 Identity = 44/110 (40.00%), Postives = 68/110 (61.82%), Query Frame = 2
Query: 824 KPKLSEELKMCSNILRDISSNRYRHLNDMFMEPVAVRFPNLSDYSSIIKKPMDLSTIRKNLDDGSYKTKNDFSEDVKLIFDNCYDYNGKDSDISKLAKDLQNIFDELFSK 1153
K KL++ LK C IL+++ S ++ F +PV L DY IIK+PMDLST++K +D Y +F+ DV+L+F NCY YN D ++ +A+ LQ++F+ F+K
Sbjct: 288 KSKLNDHLKYCDTILKEMLSKKHAAYAWPFYKPVDAEALELHDYHEIIKQPMDLSTVKKKMDSREYPDAQNFAADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMKFAK 397 HSP 4 Score: 89.3521 bits (220), Expect = 1.084e-17 Identity = 39/101 (38.61%), Postives = 64/101 (63.37%), Query Frame = 2
Query: 233 ILPQLMRHK---YSFPFLHPVDHAALNIPDYPKIIHYPMDFTTVKNRLIKKFYYNADECITDIRLVFQNCYIFNPPEIDLISMTLTLENIFNSKLDKLPSQ 526
IL +++ K Y++PF PVD AL + DY +II PMD +TVK ++ + Y +A D+RL+F NCY +NPP+ ++++M L+++F K K+P +
Sbjct: 301 ILKEMLSKKHAAYAWPFYKPVDAEALELHDYHEIIKQPMDLSTVKKKMDSREYPDAQNFAADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMKFAKMPDE 401 HSP 5 Score: 64.6994 bits (156), Expect = 3.803e-10 Identity = 31/75 (41.33%), Postives = 42/75 (56.00%), Query Frame = 2
Query: 911 FMEPVAVRFPNLSDYSSIIKKPMDLSTIRKNLDDGSYKTKNDFSEDVKLIFDNCYDYNGKDSDISKLAKDLQNIF 1135
F PV NL DY +IK PMD+ TI+K L++ Y T + +D +F NCY YN DI +A+ L+ IF
Sbjct: 55 FYTPVDAIKLNLPDYHKVIKNPMDMGTIKKRLENNYYWTAGECMQDFNTMFTNCYIYNKPTDDIVLMAQALEKIF 129
BLAST of Bromodomain containing 2 vs. Ensembl Zebrafish
Match: brd2b (bromodomain containing 2b [Source:ZFIN;Acc:ZDB-GENE-070220-1]) HSP 1 Score: 113.235 bits (282), Expect = 3.497e-26 Identity = 52/83 (62.65%), Postives = 67/83 (80.72%), Query Frame = 2
Query: 1658 LPSKTNRVTEDCKPMSYDDKRKLSMDINQLPGDKLGRIVQIIQEREPTLRDSNPDEIEIDFEVLHPVTLRELQKFVQSVLSRQ 1906
LP + ED PMSYDDKR+LS+DIN+LPG+KLGR+V IIQ REP+LRD+NP+EIEIDFE L P TLREL+++V + L ++
Sbjct: 237 LPHYDSEEEEDGLPMSYDDKRQLSLDINKLPGEKLGRVVHIIQSREPSLRDTNPEEIEIDFETLKPSTLRELERYVMTCLRKK 319 HSP 2 Score: 67.781 bits (164), Expect = 3.040e-11 Identity = 27/59 (45.76%), Postives = 41/59 (69.49%), Query Frame = 2
Query: 977 MDLSTIRKNLDDGSYKTKNDFSEDVKLIFDNCYDYNGKDSDISKLAKDLQNIFDELFSK 1153
MDLSTI++ +D+ Y+ FS DV+L+F NCY YN D D+ +A+ LQ++F+ F+K
Sbjct: 1 MDLSTIKRKMDEREYREAQQFSADVRLMFSNCYKYNPPDHDVVSMARKLQDVFEFRFAK 59 HSP 3 Score: 63.929 bits (154), Expect = 4.829e-10 Identity = 23/64 (35.94%), Postives = 43/64 (67.19%), Query Frame = 2
Query: 338 MDFTTVKNRLIKKFYYNADECITDIRLVFQNCYIFNPPEIDLISMTLTLENIFNSKLDKLPSQE 529
MD +T+K ++ ++ Y A + D+RL+F NCY +NPP+ D++SM L+++F + K+P ++
Sbjct: 1 MDLSTIKRKMDEREYREAQQFSADVRLMFSNCYKYNPPDHDVVSMARKLQDVFEFRFAKMPDED 64
BLAST of Bromodomain containing 2 vs. Ensembl Zebrafish
Match: brd4 (bromodomain containing 4 [Source:NCBI gene;Acc:570531]) HSP 1 Score: 117.472 bits (293), Expect = 4.045e-26 Identity = 51/74 (68.92%), Postives = 65/74 (87.84%), Query Frame = 2
Query: 1685 EDCKPMSYDDKRKLSMDINQLPGDKLGRIVQIIQEREPTLRDSNPDEIEIDFEVLHPVTLRELQKFVQSVLSRQ 1906
E CKPMSY++KR+LS+DIN+LPGDKLGR+V IIQ REP+L++SNPDEIEIDFE L P TLREL+++V S L ++
Sbjct: 653 EKCKPMSYEEKRQLSLDINKLPGDKLGRVVHIIQSREPSLKNSNPDEIEIDFETLKPSTLRELERYVSSCLRKK 726 HSP 2 Score: 115.161 bits (287), Expect = 1.710e-25 Identity = 51/109 (46.79%), Postives = 72/109 (66.06%), Query Frame = 2
Query: 203 TNRLQFIKKKILPQLMRHKYSFPFLHPVDHAALNIPDYPKIIHYPMDFTTVKNRLIKKFYYNADECITDIRLVFQNCYIFNPPEIDLISMTLTLENIFNSKLDKLPSQE 529
TN+LQ++ K +L L +H++++PF PVD LN+PDY KII PMD T+K RL FY +A ECI D +F NCYI+N P D++ M LE +F +K+ ++P QE
Sbjct: 45 TNQLQYLLKVVLKSLWKHQFAWPFHAPVDAVKLNLPDYYKIIKNPMDMGTIKKRLESAFYTSAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKVFLTKISEMPQQE 153 HSP 3 Score: 100.908 bits (250), Expect = 4.593e-21 Identity = 44/109 (40.37%), Postives = 68/109 (62.39%), Query Frame = 2
Query: 827 PKLSEELKMCSNILRDISSNRYRHLNDMFMEPVAVRFPNLSDYSSIIKKPMDLSTIRKNLDDGSYKTKNDFSEDVKLIFDNCYDYNGKDSDISKLAKDLQNIFDELFSK 1153
PK E+L+ CS I++D+ + ++ F +PV V L DY IIK PMDLSTI+ L+ Y+ +F+ DV+L+F NCY YN D ++ +A+ LQ++F+ F+K
Sbjct: 358 PKQQEQLRYCSGIVKDMFAKKHAAYAWPFYKPVDVDTLGLHDYHDIIKHPMDLSTIKDKLETRQYREAQEFAADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRFAK 466 HSP 4 Score: 87.4261 bits (215), Expect = 5.817e-17 Identity = 35/87 (40.23%), Postives = 57/87 (65.52%), Query Frame = 2
Query: 260 YSFPFLHPVDHAALNIPDYPKIIHYPMDFTTVKNRLIKKFYYNADECITDIRLVFQNCYIFNPPEIDLISMTLTLENIFNSKLDKLP 520
Y++PF PVD L + DY II +PMD +T+K++L + Y A E D+RL+F NCY +NPP+ ++++M L+++F + K+P
Sbjct: 382 YAWPFYKPVDVDTLGLHDYHDIIKHPMDLSTIKDKLETRQYREAQEFAADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRFAKMP 468 HSP 5 Score: 65.4698 bits (158), Expect = 3.633e-10 Identity = 34/93 (36.56%), Postives = 52/93 (55.91%), Query Frame = 2
Query: 863 ILRDISSNRYRH-LNDMFMEPV-AVRFPNLSDYSSIIKKPMDLSTIRKNLDDGSYKTKNDFSEDVKLIFDNCYDYNGKDSDISKLAKDLQNIF 1135
+L+ + + ++H F PV AV+ NL DY IIK PMD+ TI+K L+ Y + + +D +F NCY YN DI +A+ L+ +F
Sbjct: 51 LLKVVLKSLWKHQFAWPFHAPVDAVKL-NLPDYYKIIKNPMDMGTIKKRLESAFYTSAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKVF 142
BLAST of Bromodomain containing 2 vs. Ensembl Xenopus
Match: kif3b (kinesin family member 3B [Source:Xenbase;Acc:XB-GENE-979232]) HSP 1 Score: 119.783 bits (299), Expect = 1.044e-26 Identity = 58/152 (38.16%), Postives = 86/152 (56.58%), Query Frame = 2
Query: 128 DCVEVSQQIDKNVDCSGKPRPANIS------------------TNRLQFIKKKILPQLMRHKYSFPFLHPVDHAALNIPDYPKIIHYPMDFTTVKNRLIKKFYYNADECITDIRLVFQNCYIFNPPEIDLISMTLTLENIFNSKLDKLPSQE 529
D VE +Q + + + +P+P N S TN+LQ++ K +L L +H++++PF PVD LN+PDY KII PMD T+K RL +Y+NA ECI D +F NCYI+N P D++ M LE +F K+ ++P +E
Sbjct: 19 DGVEGAQMSGQQLPAAPQPQPQNSSLLNPPPPDIARPSQAKRQTNQLQYLLKTVLKTLWKHQFAWPFQLPVDVVKLNLPDYHKIIKNPMDMGTIKKRLENHYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLFLQKISEMPQEE 170 HSP 2 Score: 114.775 bits (286), Expect = 3.022e-25 Identity = 49/75 (65.33%), Postives = 66/75 (88.00%), Query Frame = 2
Query: 1682 TEDCKPMSYDDKRKLSMDINQLPGDKLGRIVQIIQEREPTLRDSNPDEIEIDFEVLHPVTLRELQKFVQSVLSRQ 1906
T+ C+PMSY++KR+LS+DIN+LPG+KLGR+V IIQ REP+L++SNPDEIEIDFE L P TLREL+++V S L ++
Sbjct: 594 TQRCRPMSYEEKRQLSLDINKLPGEKLGRVVHIIQSREPSLKNSNPDEIEIDFETLKPSTLRELERYVTSCLRKK 668 HSP 3 Score: 63.929 bits (154), Expect = 1.356e-9 Identity = 33/92 (35.87%), Postives = 49/92 (53.26%), Query Frame = 2
Query: 863 ILRDISSNRYRH-LNDMFMEPVAVRFPNLSDYSSIIKKPMDLSTIRKNLDDGSYKTKNDFSEDVKLIFDNCYDYNGKDSDISKLAKDLQNIF 1135
+L+ + ++H F PV V NL DY IIK PMD+ TI+K L++ Y + +D +F NCY YN DI +A+ L+ +F
Sbjct: 68 LLKTVLKTLWKHQFAWPFQLPVDVVKLNLPDYHKIIKNPMDMGTIKKRLENHYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLF 159
BLAST of Bromodomain containing 2 vs. Ensembl Xenopus
Match: kif3b (kinesin family member 3B [Source:Xenbase;Acc:XB-GENE-979232]) HSP 1 Score: 119.783 bits (299), Expect = 1.102e-26 Identity = 58/152 (38.16%), Postives = 86/152 (56.58%), Query Frame = 2
Query: 128 DCVEVSQQIDKNVDCSGKPRPANIS------------------TNRLQFIKKKILPQLMRHKYSFPFLHPVDHAALNIPDYPKIIHYPMDFTTVKNRLIKKFYYNADECITDIRLVFQNCYIFNPPEIDLISMTLTLENIFNSKLDKLPSQE 529
D VE +Q + + + +P+P N S TN+LQ++ K +L L +H++++PF PVD LN+PDY KII PMD T+K RL +Y+NA ECI D +F NCYI+N P D++ M LE +F K+ ++P +E
Sbjct: 19 DGVEGAQMSGQQLPAAPQPQPQNSSLLNPPPPDIARPSQAKRQTNQLQYLLKTVLKTLWKHQFAWPFQLPVDVVKLNLPDYHKIIKNPMDMGTIKKRLENHYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLFLQKISEMPQEE 170 HSP 2 Score: 114.775 bits (286), Expect = 3.296e-25 Identity = 49/75 (65.33%), Postives = 66/75 (88.00%), Query Frame = 2
Query: 1682 TEDCKPMSYDDKRKLSMDINQLPGDKLGRIVQIIQEREPTLRDSNPDEIEIDFEVLHPVTLRELQKFVQSVLSRQ 1906
T+ C+PMSY++KR+LS+DIN+LPG+KLGR+V IIQ REP+L++SNPDEIEIDFE L P TLREL+++V S L ++
Sbjct: 637 TQRCRPMSYEEKRQLSLDINKLPGEKLGRVVHIIQSREPSLKNSNPDEIEIDFETLKPSTLRELERYVTSCLRKK 711 HSP 3 Score: 100.523 bits (249), Expect = 8.821e-21 Identity = 43/108 (39.81%), Postives = 69/108 (63.89%), Query Frame = 2
Query: 830 KLSEELKMCSNILRDISSNRYRHLNDMFMEPVAVRFPNLSDYSSIIKKPMDLSTIRKNLDDGSYKTKNDFSEDVKLIFDNCYDYNGKDSDISKLAKDLQNIFDELFSK 1153
K SE+L+ C+ I+R++ S +++ F +PV V L DY IIK PMDL TI+ +D+ YK +F+ DV+L+F NCY YN D ++ +A+ LQ++F+ ++K
Sbjct: 374 KTSEQLRYCAGIIREMFSKKHQAYAWPFYKPVDVDALGLHDYREIIKHPMDLGTIKVKMDNWDYKDAKEFASDVRLMFSNCYKYNPPDHEVVIMARKLQDVFEMRYAK 481 HSP 4 Score: 82.0333 bits (201), Expect = 3.718e-15 Identity = 34/86 (39.53%), Postives = 56/86 (65.12%), Query Frame = 2
Query: 260 YSFPFLHPVDHAALNIPDYPKIIHYPMDFTTVKNRLIKKFYYNADECITDIRLVFQNCYIFNPPEIDLISMTLTLENIFNSKLDKL 517
Y++PF PVD AL + DY +II +PMD T+K ++ Y +A E +D+RL+F NCY +NPP+ +++ M L+++F + K+
Sbjct: 397 YAWPFYKPVDVDALGLHDYREIIKHPMDLGTIKVKMDNWDYKDAKEFASDVRLMFSNCYKYNPPDHEVVIMARKLQDVFEMRYAKM 482 HSP 5 Score: 63.929 bits (154), Expect = 1.438e-9 Identity = 33/92 (35.87%), Postives = 49/92 (53.26%), Query Frame = 2
Query: 863 ILRDISSNRYRH-LNDMFMEPVAVRFPNLSDYSSIIKKPMDLSTIRKNLDDGSYKTKNDFSEDVKLIFDNCYDYNGKDSDISKLAKDLQNIF 1135
+L+ + ++H F PV V NL DY IIK PMD+ TI+K L++ Y + +D +F NCY YN DI +A+ L+ +F
Sbjct: 68 LLKTVLKTLWKHQFAWPFQLPVDVVKLNLPDYHKIIKNPMDMGTIKKRLENHYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLF 159
BLAST of Bromodomain containing 2 vs. Ensembl Xenopus
Match: kif3b (kinesin family member 3B [Source:Xenbase;Acc:XB-GENE-979232]) HSP 1 Score: 119.398 bits (298), Expect = 1.303e-26 Identity = 58/152 (38.16%), Postives = 86/152 (56.58%), Query Frame = 2
Query: 128 DCVEVSQQIDKNVDCSGKPRPANIS------------------TNRLQFIKKKILPQLMRHKYSFPFLHPVDHAALNIPDYPKIIHYPMDFTTVKNRLIKKFYYNADECITDIRLVFQNCYIFNPPEIDLISMTLTLENIFNSKLDKLPSQE 529
D VE +Q + + + +P+P N S TN+LQ++ K +L L +H++++PF PVD LN+PDY KII PMD T+K RL +Y+NA ECI D +F NCYI+N P D++ M LE +F K+ ++P +E
Sbjct: 19 DGVEGAQMSGQQLPAAPQPQPQNSSLLNPPPPDIARPSQAKRQTNQLQYLLKTVLKTLWKHQFAWPFQLPVDVVKLNLPDYHKIIKNPMDMGTIKKRLENHYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLFLQKISEMPQEE 170 HSP 2 Score: 114.775 bits (286), Expect = 3.735e-25 Identity = 49/75 (65.33%), Postives = 66/75 (88.00%), Query Frame = 2
Query: 1682 TEDCKPMSYDDKRKLSMDINQLPGDKLGRIVQIIQEREPTLRDSNPDEIEIDFEVLHPVTLRELQKFVQSVLSRQ 1906
T+ C+PMSY++KR+LS+DIN+LPG+KLGR+V IIQ REP+L++SNPDEIEIDFE L P TLREL+++V S L ++
Sbjct: 637 TQRCRPMSYEEKRQLSLDINKLPGEKLGRVVHIIQSREPSLKNSNPDEIEIDFETLKPSTLRELERYVTSCLRKK 711 HSP 3 Score: 100.523 bits (249), Expect = 8.505e-21 Identity = 43/108 (39.81%), Postives = 69/108 (63.89%), Query Frame = 2
Query: 830 KLSEELKMCSNILRDISSNRYRHLNDMFMEPVAVRFPNLSDYSSIIKKPMDLSTIRKNLDDGSYKTKNDFSEDVKLIFDNCYDYNGKDSDISKLAKDLQNIFDELFSK 1153
K SE+L+ C+ I+R++ S +++ F +PV V L DY IIK PMDL TI+ +D+ YK +F+ DV+L+F NCY YN D ++ +A+ LQ++F+ ++K
Sbjct: 374 KTSEQLRYCAGIIREMFSKKHQAYAWPFYKPVDVDALGLHDYREIIKHPMDLGTIKVKMDNWDYKDAKEFASDVRLMFSNCYKYNPPDHEVVIMARKLQDVFEMRYAK 481 HSP 4 Score: 82.0333 bits (201), Expect = 4.474e-15 Identity = 34/86 (39.53%), Postives = 56/86 (65.12%), Query Frame = 2
Query: 260 YSFPFLHPVDHAALNIPDYPKIIHYPMDFTTVKNRLIKKFYYNADECITDIRLVFQNCYIFNPPEIDLISMTLTLENIFNSKLDKL 517
Y++PF PVD AL + DY +II +PMD T+K ++ Y +A E +D+RL+F NCY +NPP+ +++ M L+++F + K+
Sbjct: 397 YAWPFYKPVDVDALGLHDYREIIKHPMDLGTIKVKMDNWDYKDAKEFASDVRLMFSNCYKYNPPDHEVVIMARKLQDVFEMRYAKM 482 HSP 5 Score: 63.929 bits (154), Expect = 1.286e-9 Identity = 33/92 (35.87%), Postives = 49/92 (53.26%), Query Frame = 2
Query: 863 ILRDISSNRYRH-LNDMFMEPVAVRFPNLSDYSSIIKKPMDLSTIRKNLDDGSYKTKNDFSEDVKLIFDNCYDYNGKDSDISKLAKDLQNIF 1135
+L+ + ++H F PV V NL DY IIK PMD+ TI+K L++ Y + +D +F NCY YN DI +A+ L+ +F
Sbjct: 68 LLKTVLKTLWKHQFAWPFQLPVDVVKLNLPDYHKIIKNPMDMGTIKKRLENHYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLF 159
BLAST of Bromodomain containing 2 vs. Ensembl Xenopus
Match: kif3b (kinesin family member 3B [Source:Xenbase;Acc:XB-GENE-979232]) HSP 1 Score: 119.398 bits (298), Expect = 1.336e-26 Identity = 58/152 (38.16%), Postives = 86/152 (56.58%), Query Frame = 2
Query: 128 DCVEVSQQIDKNVDCSGKPRPANIS------------------TNRLQFIKKKILPQLMRHKYSFPFLHPVDHAALNIPDYPKIIHYPMDFTTVKNRLIKKFYYNADECITDIRLVFQNCYIFNPPEIDLISMTLTLENIFNSKLDKLPSQE 529
D VE +Q + + + +P+P N S TN+LQ++ K +L L +H++++PF PVD LN+PDY KII PMD T+K RL +Y+NA ECI D +F NCYI+N P D++ M LE +F K+ ++P +E
Sbjct: 19 DGVEGAQMSGQQLPAAPQPQPQNSSLLNPPPPDIARPSQAKRQTNQLQYLLKTVLKTLWKHQFAWPFQLPVDVVKLNLPDYHKIIKNPMDMGTIKKRLENHYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLFLQKISEMPQEE 170 HSP 2 Score: 114.39 bits (285), Expect = 4.198e-25 Identity = 49/75 (65.33%), Postives = 66/75 (88.00%), Query Frame = 2
Query: 1682 TEDCKPMSYDDKRKLSMDINQLPGDKLGRIVQIIQEREPTLRDSNPDEIEIDFEVLHPVTLRELQKFVQSVLSRQ 1906
T+ C+PMSY++KR+LS+DIN+LPG+KLGR+V IIQ REP+L++SNPDEIEIDFE L P TLREL+++V S L ++
Sbjct: 592 TQRCRPMSYEEKRQLSLDINKLPGEKLGRVVHIIQSREPSLKNSNPDEIEIDFETLKPSTLRELERYVTSCLRKK 666 HSP 3 Score: 100.523 bits (249), Expect = 7.855e-21 Identity = 43/108 (39.81%), Postives = 69/108 (63.89%), Query Frame = 2
Query: 830 KLSEELKMCSNILRDISSNRYRHLNDMFMEPVAVRFPNLSDYSSIIKKPMDLSTIRKNLDDGSYKTKNDFSEDVKLIFDNCYDYNGKDSDISKLAKDLQNIFDELFSK 1153
K SE+L+ C+ I+R++ S +++ F +PV V L DY IIK PMDL TI+ +D+ YK +F+ DV+L+F NCY YN D ++ +A+ LQ++F+ ++K
Sbjct: 343 KTSEQLRYCAGIIREMFSKKHQAYAWPFYKPVDVDALGLHDYREIIKHPMDLGTIKVKMDNWDYKDAKEFASDVRLMFSNCYKYNPPDHEVVIMARKLQDVFEMRYAK 450 HSP 4 Score: 82.0333 bits (201), Expect = 3.936e-15 Identity = 34/86 (39.53%), Postives = 56/86 (65.12%), Query Frame = 2
Query: 260 YSFPFLHPVDHAALNIPDYPKIIHYPMDFTTVKNRLIKKFYYNADECITDIRLVFQNCYIFNPPEIDLISMTLTLENIFNSKLDKL 517
Y++PF PVD AL + DY +II +PMD T+K ++ Y +A E +D+RL+F NCY +NPP+ +++ M L+++F + K+
Sbjct: 366 YAWPFYKPVDVDALGLHDYREIIKHPMDLGTIKVKMDNWDYKDAKEFASDVRLMFSNCYKYNPPDHEVVIMARKLQDVFEMRYAKM 451 HSP 5 Score: 64.3142 bits (155), Expect = 1.150e-9 Identity = 33/92 (35.87%), Postives = 49/92 (53.26%), Query Frame = 2
Query: 863 ILRDISSNRYRH-LNDMFMEPVAVRFPNLSDYSSIIKKPMDLSTIRKNLDDGSYKTKNDFSEDVKLIFDNCYDYNGKDSDISKLAKDLQNIF 1135
+L+ + ++H F PV V NL DY IIK PMD+ TI+K L++ Y + +D +F NCY YN DI +A+ L+ +F
Sbjct: 68 LLKTVLKTLWKHQFAWPFQLPVDVVKLNLPDYHKIIKNPMDMGTIKKRLENHYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLF 159
BLAST of Bromodomain containing 2 vs. Ensembl Xenopus
Match: brd3 (bromodomain containing 3 [Source:NCBI gene;Acc:733891]) HSP 1 Score: 115.931 bits (289), Expect = 1.045e-25 Identity = 50/74 (67.57%), Postives = 65/74 (87.84%), Query Frame = 2
Query: 1685 EDCKPMSYDDKRKLSMDINQLPGDKLGRIVQIIQEREPTLRDSNPDEIEIDFEVLHPVTLRELQKFVQSVLSRQ 1906
E+ PM+YD+KR+LS+DIN+LPG+KLGR+V IIQ REP+LRDSNPDEIEIDFE L P TLREL+++V+S L ++
Sbjct: 637 EESLPMTYDEKRQLSLDINRLPGEKLGRVVHIIQSREPSLRDSNPDEIEIDFETLKPTTLRELERYVKSCLQKK 710 HSP 2 Score: 112.079 bits (279), Expect = 1.634e-24 Identity = 46/109 (42.20%), Postives = 72/109 (66.06%), Query Frame = 2
Query: 203 TNRLQFIKKKILPQLMRHKYSFPFLHPVDHAALNIPDYPKIIHYPMDFTTVKNRLIKKFYYNADECITDIRLVFQNCYIFNPPEIDLISMTLTLENIFNSKLDKLPSQE 529
TN+LQ+++ ++ L +H++++PF PVD LN+PDY KII PMD T+K RL +Y++A+EC+ D +F NCYI+N D++ M LE IF K+ ++P +E
Sbjct: 32 TNQLQYMQNVVVKTLWKHQFAWPFYQPVDCVKLNLPDYHKIIKNPMDMGTIKKRLENNYYWSANECMQDFNTMFTNCYIYNKSTDDIVLMAQALEKIFLQKVAQMPQEE 140 HSP 3 Score: 95.5153 bits (236), Expect = 2.295e-19 Identity = 42/110 (38.18%), Postives = 67/110 (60.91%), Query Frame = 2
Query: 824 KPKLSEELKMCSNILRDISSNRYRHLNDMFMEPVAVRFPNLSDYSSIIKKPMDLSTIRKNLDDGSYKTKNDFSEDVKLIFDNCYDYNGKDSDISKLAKDLQNIFDELFSK 1153
K KL+E LK C +IL+++ S ++ F +PV L DY IIK PMDLS++++ +D Y F+ D++L+F NCY YN D ++ +A+ LQ++F+ F+K
Sbjct: 357 KGKLNEHLKYCDSILKEMLSKKHAAYAWPFYKPVDAEALELHDYHDIIKHPMDLSSVKRKMDAREYADAQAFAADIRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRFAK 466 HSP 4 Score: 89.7373 bits (221), Expect = 1.233e-17 Identity = 38/101 (37.62%), Postives = 64/101 (63.37%), Query Frame = 2
Query: 233 ILPQLMRHK---YSFPFLHPVDHAALNIPDYPKIIHYPMDFTTVKNRLIKKFYYNADECITDIRLVFQNCYIFNPPEIDLISMTLTLENIFNSKLDKLPSQ 526
IL +++ K Y++PF PVD AL + DY II +PMD ++VK ++ + Y +A DIRL+F NCY +NPP+ ++++M L+++F + K+P +
Sbjct: 370 ILKEMLSKKHAAYAWPFYKPVDAEALELHDYHDIIKHPMDLSSVKRKMDAREYADAQAFAADIRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRFAKMPDE 470 HSP 5 Score: 67.3958 bits (163), Expect = 1.117e-10 Identity = 32/75 (42.67%), Postives = 44/75 (58.67%), Query Frame = 2
Query: 911 FMEPVAVRFPNLSDYSSIIKKPMDLSTIRKNLDDGSYKTKNDFSEDVKLIFDNCYDYNGKDSDISKLAKDLQNIF 1135
F +PV NL DY IIK PMD+ TI+K L++ Y + N+ +D +F NCY YN DI +A+ L+ IF
Sbjct: 55 FYQPVDCVKLNLPDYHKIIKNPMDMGTIKKRLENNYYWSANECMQDFNTMFTNCYIYNKSTDDIVLMAQALEKIF 129
BLAST of Bromodomain containing 2 vs. Ensembl Mouse
Match: Brd4 (bromodomain containing 4 [Source:MGI Symbol;Acc:MGI:1888520]) HSP 1 Score: 120.553 bits (301), Expect = 9.380e-28 Identity = 59/155 (38.06%), Postives = 87/155 (56.13%), Query Frame = 2
Query: 119 VSDDCVEVSQQIDKNVDCSGKPRPANIS------------------TNRLQFIKKKILPQLMRHKYSFPFLHPVDHAALNIPDYPKIIHYPMDFTTVKNRLIKKFYYNADECITDIRLVFQNCYIFNPPEIDLISMTLTLENIFNSKLDKLPSQE 529
V D +E SQ +P+PAN + TN+LQ++ + +L L +H++++PF PVD LN+PDY KII PMD T+K RL +Y+NA ECI D +F NCYI+N P D++ M LE +F K+++LP++E
Sbjct: 16 VMGDGLETSQM--STTQAQAQPQPANAASTNPPPPETSNPNKPKRQTNQLQYLLRVVLKTLWKHQFAWPFQQPVDAVKLNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLFLQKINELPTEE 168 HSP 2 Score: 100.908 bits (250), Expect = 1.639e-21 Identity = 44/108 (40.74%), Postives = 68/108 (62.96%), Query Frame = 2
Query: 830 KLSEELKMCSNILRDISSNRYRHLNDMFMEPVAVRFPNLSDYSSIIKKPMDLSTIRKNLDDGSYKTKNDFSEDVKLIFDNCYDYNGKDSDISKLAKDLQNIFDELFSK 1153
K+SE+LK CS IL+++ + ++ F +PV V L DY IIK PMD+STI+ L+ Y+ +F DV+L+F NCY YN D ++ +A+ LQ++F+ F+K
Sbjct: 350 KISEQLKCCSGILKEMFAKKHAAYAWPFYKPVDVEALGLHDYCDIIKHPMDMSTIKSKLESREYRDAQEFGADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRFAK 457 HSP 3 Score: 88.1965 bits (217), Expect = 1.582e-17 Identity = 36/89 (40.45%), Postives = 60/89 (67.42%), Query Frame = 2
Query: 260 YSFPFLHPVDHAALNIPDYPKIIHYPMDFTTVKNRLIKKFYYNADECITDIRLVFQNCYIFNPPEIDLISMTLTLENIFNSKLDKLPSQ 526
Y++PF PVD AL + DY II +PMD +T+K++L + Y +A E D+RL+F NCY +NPP+ ++++M L+++F + K+P +
Sbjct: 373 YAWPFYKPVDVEALGLHDYCDIIKHPMDMSTIKSKLESREYRDAQEFGADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRFAKMPDE 461 HSP 4 Score: 65.855 bits (159), Expect = 1.638e-10 Identity = 35/93 (37.63%), Postives = 52/93 (55.91%), Query Frame = 2
Query: 863 ILRDISSNRYRH-LNDMFMEPV-AVRFPNLSDYSSIIKKPMDLSTIRKNLDDGSYKTKNDFSEDVKLIFDNCYDYNGKDSDISKLAKDLQNIF 1135
+LR + ++H F +PV AV+ NL DY IIK PMD+ TI+K L++ Y + +D +F NCY YN DI +A+ L+ +F
Sbjct: 66 LLRVVLKTLWKHQFAWPFQQPVDAVKL-NLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLF 157
BLAST of Bromodomain containing 2 vs. Ensembl Mouse
Match: Brd4 (bromodomain containing 4 [Source:MGI Symbol;Acc:MGI:1888520]) HSP 1 Score: 120.553 bits (301), Expect = 1.064e-27 Identity = 59/155 (38.06%), Postives = 87/155 (56.13%), Query Frame = 2
Query: 119 VSDDCVEVSQQIDKNVDCSGKPRPANIS------------------TNRLQFIKKKILPQLMRHKYSFPFLHPVDHAALNIPDYPKIIHYPMDFTTVKNRLIKKFYYNADECITDIRLVFQNCYIFNPPEIDLISMTLTLENIFNSKLDKLPSQE 529
V D +E SQ +P+PAN + TN+LQ++ + +L L +H++++PF PVD LN+PDY KII PMD T+K RL +Y+NA ECI D +F NCYI+N P D++ M LE +F K+++LP++E
Sbjct: 16 VMGDGLETSQM--STTQAQAQPQPANAASTNPPPPETSNPNKPKRQTNQLQYLLRVVLKTLWKHQFAWPFQQPVDAVKLNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLFLQKINELPTEE 168 HSP 2 Score: 100.908 bits (250), Expect = 1.702e-21 Identity = 44/108 (40.74%), Postives = 68/108 (62.96%), Query Frame = 2
Query: 830 KLSEELKMCSNILRDISSNRYRHLNDMFMEPVAVRFPNLSDYSSIIKKPMDLSTIRKNLDDGSYKTKNDFSEDVKLIFDNCYDYNGKDSDISKLAKDLQNIFDELFSK 1153
K+SE+LK CS IL+++ + ++ F +PV V L DY IIK PMD+STI+ L+ Y+ +F DV+L+F NCY YN D ++ +A+ LQ++F+ F+K
Sbjct: 350 KISEQLKCCSGILKEMFAKKHAAYAWPFYKPVDVEALGLHDYCDIIKHPMDMSTIKSKLESREYRDAQEFGADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRFAK 457 HSP 3 Score: 88.1965 bits (217), Expect = 1.707e-17 Identity = 36/89 (40.45%), Postives = 60/89 (67.42%), Query Frame = 2
Query: 260 YSFPFLHPVDHAALNIPDYPKIIHYPMDFTTVKNRLIKKFYYNADECITDIRLVFQNCYIFNPPEIDLISMTLTLENIFNSKLDKLPSQ 526
Y++PF PVD AL + DY II +PMD +T+K++L + Y +A E D+RL+F NCY +NPP+ ++++M L+++F + K+P +
Sbjct: 373 YAWPFYKPVDVEALGLHDYCDIIKHPMDMSTIKSKLESREYRDAQEFGADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRFAKMPDE 461 HSP 4 Score: 65.855 bits (159), Expect = 1.621e-10 Identity = 35/93 (37.63%), Postives = 52/93 (55.91%), Query Frame = 2
Query: 863 ILRDISSNRYRH-LNDMFMEPV-AVRFPNLSDYSSIIKKPMDLSTIRKNLDDGSYKTKNDFSEDVKLIFDNCYDYNGKDSDISKLAKDLQNIF 1135
+LR + ++H F +PV AV+ NL DY IIK PMD+ TI+K L++ Y + +D +F NCY YN DI +A+ L+ +F
Sbjct: 66 LLRVVLKTLWKHQFAWPFQQPVDAVKL-NLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLF 157
BLAST of Bromodomain containing 2 vs. Ensembl Mouse
Match: Brd4 (bromodomain containing 4 [Source:MGI Symbol;Acc:MGI:1888520]) HSP 1 Score: 120.553 bits (301), Expect = 1.826e-27 Identity = 59/155 (38.06%), Postives = 87/155 (56.13%), Query Frame = 2
Query: 119 VSDDCVEVSQQIDKNVDCSGKPRPANIS------------------TNRLQFIKKKILPQLMRHKYSFPFLHPVDHAALNIPDYPKIIHYPMDFTTVKNRLIKKFYYNADECITDIRLVFQNCYIFNPPEIDLISMTLTLENIFNSKLDKLPSQE 529
V D +E SQ +P+PAN + TN+LQ++ + +L L +H++++PF PVD LN+PDY KII PMD T+K RL +Y+NA ECI D +F NCYI+N P D++ M LE +F K+++LP++E
Sbjct: 16 VMGDGLETSQM--STTQAQAQPQPANAASTNPPPPETSNPNKPKRQTNQLQYLLRVVLKTLWKHQFAWPFQQPVDAVKLNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLFLQKINELPTEE 168 HSP 2 Score: 113.62 bits (283), Expect = 3.457e-25 Identity = 49/72 (68.06%), Postives = 64/72 (88.89%), Query Frame = 2
Query: 1691 CKPMSYDDKRKLSMDINQLPGDKLGRIVQIIQEREPTLRDSNPDEIEIDFEVLHPVTLRELQKFVQSVLSRQ 1906
CKPMSY++KR+LS+DIN+LPG+KLGR+V IIQ REP+L++SNPDEIEIDFE L P TLREL+++V S L ++
Sbjct: 608 CKPMSYEEKRQLSLDINKLPGEKLGRVVHIIQSREPSLKNSNPDEIEIDFETLKPSTLRELERYVTSCLRKK 679 HSP 3 Score: 101.293 bits (251), Expect = 2.473e-21 Identity = 44/108 (40.74%), Postives = 68/108 (62.96%), Query Frame = 2
Query: 830 KLSEELKMCSNILRDISSNRYRHLNDMFMEPVAVRFPNLSDYSSIIKKPMDLSTIRKNLDDGSYKTKNDFSEDVKLIFDNCYDYNGKDSDISKLAKDLQNIFDELFSK 1153
K+SE+LK CS IL+++ + ++ F +PV V L DY IIK PMD+STI+ L+ Y+ +F DV+L+F NCY YN D ++ +A+ LQ++F+ F+K
Sbjct: 350 KISEQLKCCSGILKEMFAKKHAAYAWPFYKPVDVEALGLHDYCDIIKHPMDMSTIKSKLESREYRDAQEFGADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRFAK 457 HSP 4 Score: 89.3521 bits (220), Expect = 1.208e-17 Identity = 36/89 (40.45%), Postives = 60/89 (67.42%), Query Frame = 2
Query: 260 YSFPFLHPVDHAALNIPDYPKIIHYPMDFTTVKNRLIKKFYYNADECITDIRLVFQNCYIFNPPEIDLISMTLTLENIFNSKLDKLPSQ 526
Y++PF PVD AL + DY II +PMD +T+K++L + Y +A E D+RL+F NCY +NPP+ ++++M L+++F + K+P +
Sbjct: 373 YAWPFYKPVDVEALGLHDYCDIIKHPMDMSTIKSKLESREYRDAQEFGADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRFAKMPDE 461 HSP 5 Score: 66.2402 bits (160), Expect = 1.459e-10 Identity = 35/93 (37.63%), Postives = 52/93 (55.91%), Query Frame = 2
Query: 863 ILRDISSNRYRH-LNDMFMEPV-AVRFPNLSDYSSIIKKPMDLSTIRKNLDDGSYKTKNDFSEDVKLIFDNCYDYNGKDSDISKLAKDLQNIF 1135
+LR + ++H F +PV AV+ NL DY IIK PMD+ TI+K L++ Y + +D +F NCY YN DI +A+ L+ +F
Sbjct: 66 LLRVVLKTLWKHQFAWPFQQPVDAVKL-NLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLF 157
BLAST of Bromodomain containing 2 vs. Ensembl Mouse
Match: Brd4 (bromodomain containing 4 [Source:MGI Symbol;Acc:MGI:1888520]) HSP 1 Score: 119.783 bits (299), Expect = 8.625e-27 Identity = 59/157 (37.58%), Postives = 88/157 (56.05%), Query Frame = 2
Query: 113 MLVSDDCVEVSQQIDKNVDCSGKPRPANIS------------------TNRLQFIKKKILPQLMRHKYSFPFLHPVDHAALNIPDYPKIIHYPMDFTTVKNRLIKKFYYNADECITDIRLVFQNCYIFNPPEIDLISMTLTLENIFNSKLDKLPSQE 529
+ V D +E SQ +P+PAN + TN+LQ++ + +L L +H++++PF PVD LN+PDY KII PMD T+K RL +Y+NA ECI D +F NCYI+N P D++ M LE +F K+++LP++E
Sbjct: 14 LPVMGDGLETSQM--STTQAQAQPQPANAASTNPPPPETSNPNKPKRQTNQLQYLLRVVLKTLWKHQFAWPFQQPVDAVKLNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLFLQKINELPTEE 168 HSP 2 Score: 113.62 bits (283), Expect = 6.048e-25 Identity = 49/72 (68.06%), Postives = 64/72 (88.89%), Query Frame = 2
Query: 1691 CKPMSYDDKRKLSMDINQLPGDKLGRIVQIIQEREPTLRDSNPDEIEIDFEVLHPVTLRELQKFVQSVLSRQ 1906
CKPMSY++KR+LS+DIN+LPG+KLGR+V IIQ REP+L++SNPDEIEIDFE L P TLREL+++V S L ++
Sbjct: 609 CKPMSYEEKRQLSLDINKLPGEKLGRVVHIIQSREPSLKNSNPDEIEIDFETLKPSTLRELERYVTSCLRKK 680 HSP 3 Score: 102.449 bits (254), Expect = 1.659e-21 Identity = 44/108 (40.74%), Postives = 68/108 (62.96%), Query Frame = 2
Query: 830 KLSEELKMCSNILRDISSNRYRHLNDMFMEPVAVRFPNLSDYSSIIKKPMDLSTIRKNLDDGSYKTKNDFSEDVKLIFDNCYDYNGKDSDISKLAKDLQNIFDELFSK 1153
K+SE+LK CS IL+++ + ++ F +PV V L DY IIK PMD+STI+ L+ Y+ +F DV+L+F NCY YN D ++ +A+ LQ++F+ F+K
Sbjct: 351 KISEQLKCCSGILKEMFAKKHAAYAWPFYKPVDVEALGLHDYCDIIKHPMDMSTIKSKLESREYRDAQEFGADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRFAK 458 HSP 4 Score: 88.9669 bits (219), Expect = 2.398e-17 Identity = 36/87 (41.38%), Postives = 59/87 (67.82%), Query Frame = 2
Query: 260 YSFPFLHPVDHAALNIPDYPKIIHYPMDFTTVKNRLIKKFYYNADECITDIRLVFQNCYIFNPPEIDLISMTLTLENIFNSKLDKLP 520
Y++PF PVD AL + DY II +PMD +T+K++L + Y +A E D+RL+F NCY +NPP+ ++++M L+++F + K+P
Sbjct: 374 YAWPFYKPVDVEALGLHDYCDIIKHPMDMSTIKSKLESREYRDAQEFGADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRFAKMP 460 HSP 5 Score: 67.3958 bits (163), Expect = 9.944e-11 Identity = 35/93 (37.63%), Postives = 52/93 (55.91%), Query Frame = 2
Query: 863 ILRDISSNRYRH-LNDMFMEPV-AVRFPNLSDYSSIIKKPMDLSTIRKNLDDGSYKTKNDFSEDVKLIFDNCYDYNGKDSDISKLAKDLQNIF 1135
+LR + ++H F +PV AV+ NL DY IIK PMD+ TI+K L++ Y + +D +F NCY YN DI +A+ L+ +F
Sbjct: 66 LLRVVLKTLWKHQFAWPFQQPVDAVKL-NLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLF 157
BLAST of Bromodomain containing 2 vs. Ensembl Mouse
Match: Brd4 (bromodomain containing 4 [Source:MGI Symbol;Acc:MGI:1888520]) HSP 1 Score: 119.783 bits (299), Expect = 8.695e-27 Identity = 59/157 (37.58%), Postives = 88/157 (56.05%), Query Frame = 2
Query: 113 MLVSDDCVEVSQQIDKNVDCSGKPRPANIS------------------TNRLQFIKKKILPQLMRHKYSFPFLHPVDHAALNIPDYPKIIHYPMDFTTVKNRLIKKFYYNADECITDIRLVFQNCYIFNPPEIDLISMTLTLENIFNSKLDKLPSQE 529
+ V D +E SQ +P+PAN + TN+LQ++ + +L L +H++++PF PVD LN+PDY KII PMD T+K RL +Y+NA ECI D +F NCYI+N P D++ M LE +F K+++LP++E
Sbjct: 14 LPVMGDGLETSQM--STTQAQAQPQPANAASTNPPPPETSNPNKPKRQTNQLQYLLRVVLKTLWKHQFAWPFQQPVDAVKLNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLFLQKINELPTEE 168 HSP 2 Score: 113.62 bits (283), Expect = 5.994e-25 Identity = 49/72 (68.06%), Postives = 64/72 (88.89%), Query Frame = 2
Query: 1691 CKPMSYDDKRKLSMDINQLPGDKLGRIVQIIQEREPTLRDSNPDEIEIDFEVLHPVTLRELQKFVQSVLSRQ 1906
CKPMSY++KR+LS+DIN+LPG+KLGR+V IIQ REP+L++SNPDEIEIDFE L P TLREL+++V S L ++
Sbjct: 608 CKPMSYEEKRQLSLDINKLPGEKLGRVVHIIQSREPSLKNSNPDEIEIDFETLKPSTLRELERYVTSCLRKK 679 HSP 3 Score: 102.449 bits (254), Expect = 1.659e-21 Identity = 44/108 (40.74%), Postives = 68/108 (62.96%), Query Frame = 2
Query: 830 KLSEELKMCSNILRDISSNRYRHLNDMFMEPVAVRFPNLSDYSSIIKKPMDLSTIRKNLDDGSYKTKNDFSEDVKLIFDNCYDYNGKDSDISKLAKDLQNIFDELFSK 1153
K+SE+LK CS IL+++ + ++ F +PV V L DY IIK PMD+STI+ L+ Y+ +F DV+L+F NCY YN D ++ +A+ LQ++F+ F+K
Sbjct: 350 KISEQLKCCSGILKEMFAKKHAAYAWPFYKPVDVEALGLHDYCDIIKHPMDMSTIKSKLESREYRDAQEFGADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRFAK 457 HSP 4 Score: 88.9669 bits (219), Expect = 2.418e-17 Identity = 36/87 (41.38%), Postives = 59/87 (67.82%), Query Frame = 2
Query: 260 YSFPFLHPVDHAALNIPDYPKIIHYPMDFTTVKNRLIKKFYYNADECITDIRLVFQNCYIFNPPEIDLISMTLTLENIFNSKLDKLP 520
Y++PF PVD AL + DY II +PMD +T+K++L + Y +A E D+RL+F NCY +NPP+ ++++M L+++F + K+P
Sbjct: 373 YAWPFYKPVDVEALGLHDYCDIIKHPMDMSTIKSKLESREYRDAQEFGADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRFAKMP 459 HSP 5 Score: 67.3958 bits (163), Expect = 9.775e-11 Identity = 35/93 (37.63%), Postives = 52/93 (55.91%), Query Frame = 2
Query: 863 ILRDISSNRYRH-LNDMFMEPV-AVRFPNLSDYSSIIKKPMDLSTIRKNLDDGSYKTKNDFSEDVKLIFDNCYDYNGKDSDISKLAKDLQNIF 1135
+LR + ++H F +PV AV+ NL DY IIK PMD+ TI+K L++ Y + +D +F NCY YN DI +A+ L+ +F
Sbjct: 66 LLRVVLKTLWKHQFAWPFQQPVDAVKL-NLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLF 157
BLAST of Bromodomain containing 2 vs. UniProt/SwissProt
Match: sp|Q4R8Y1|BRDT_MACFA (Bromodomain testis-specific protein OS=Macaca fascicularis OX=9541 GN=BRDT PE=2 SV=3) HSP 1 Score: 162.925 bits (411), Expect = 1.438e-39 Identity = 112/354 (31.64%), Postives = 176/354 (49.72%), Query Frame = 2
Query: 203 TNRLQFIKKKILPQLMRHKYSFPFLHPVDHAALNIPDYPKIIHYPMDFTTVKNRLIKKFYYNADECITDIRLVFQNCYIFNPPEIDLISMTLTLENIFNSKLDKLPSQEXXXXXXXXXXXXXXXXXXXXXXXEPVCDIKKSLRPTTKRLKXXXXXXXXXXXXXXXCSISPDAK-----------SKAKKRKVE------SCYDLSPTPSPSISLKNESLDEIPIKPKLSEEL----KMCSNILRDIS-SNRYRHLNDMFME---------------PVAVRFPNLSDYSSIIKKPMDLSTIRKNLDDGSYKTKNDFSEDVKLIFDNCYDYNGKDSDISKLAKDLQNIFDELFSK 1153
TN+LQ+++K +L L +H +S+PF PVD L +PDY II PMD T+K RL K+Y A ECI D +F NCY++N P D++ M LE +F KL ++P +E + K +I S+ E K S T K K + + T+ S +++ A +K KRK + S S SP+ + K+ +L PIK + + + + N+++ + + + RH +++ E PV V L +Y I+K PMDL TI++ +D+ YK F+ DV+L+F NCY YN D ++ +A+ LQ++F+ FSK
Sbjct: 29 TNQLQYLQKVVLKDLWKHSFSWPFQRPVDAVKLKLPDYYTIIKNPMDLNTIKKRLENKYYVKASECIEDFNTMFSNCYLYNKPGDDIVLMAQALEKLFVQKLSQMPQEEQVVGGKERIKKGTQQNIAVFSAKE-----KSSPNATEKVFKQQAIPSVFPKTSVSPLNVAQGASVNSSSQSVAQVTKGVKRKADTTTPATSVVKASSEFSPTFTEKSVTLP--PIKENMPKNVLPDSQQQYNVVKSVKVTEQLRHCSEILKEMLAKKHFSYAWPFYNPVDVNALGLHNYYDIVKNPMDLGTIKEKMDNQEYKDAYKFAADVRLMFMNCYKYNPPDHEVVTMARMLQDVFETHFSK 375 HSP 2 Score: 106.686 bits (265), Expect = 4.377e-22 Identity = 47/74 (63.51%), Postives = 63/74 (85.14%), Query Frame = 2
Query: 1685 EDCKPMSYDDKRKLSMDINQLPGDKLGRIVQIIQEREPTLRDSNPDEIEIDFEVLHPVTLRELQKFVQSVLSRQ 1906
++ KPM+YD+KR+LS++IN+LPGDKLGR+V IIQ REP+L +SNPDEIEIDFE L TLREL+K+V + L ++
Sbjct: 505 DNAKPMNYDEKRQLSLNINKLPGDKLGRVVHIIQSREPSLSNSNPDEIEIDFETLKASTLRELEKYVSACLRKR 578 HSP 3 Score: 82.8037 bits (203), Expect = 9.972e-15 Identity = 35/100 (35.00%), Postives = 64/100 (64.00%), Query Frame = 2
Query: 230 KILPQLMRHK---YSFPFLHPVDHAALNIPDYPKIIHYPMDFTTVKNRLIKKFYYNADECITDIRLVFQNCYIFNPPEIDLISMTLTLENIFNSKLDKLP 520
+IL +++ K Y++PF +PVD AL + +Y I+ PMD T+K ++ + Y +A + D+RL+F NCY +NPP+ ++++M L+++F + K+P
Sbjct: 278 EILKEMLAKKHFSYAWPFYNPVDVNALGLHNYYDIVKNPMDLGTIKEKMDNQEYKDAYKFAADVRLMFMNCYKYNPPDHEVVTMARMLQDVFETHFSKIP 377 HSP 4 Score: 64.6994 bits (156), Expect = 3.898e-9 Identity = 49/155 (31.61%), Postives = 76/155 (49.03%), Query Frame = 2
Query: 863 ILRDISSNRYRH-LNDMFMEPVAVRFPNLSDYSSIIKKPMDLSTIRKNLDDGSYKTKNDFSEDVKLIFDNCYDYNGKDSDISKLAKDLQNIFDELFSKQFNLSKPQPSQVQNSKIKSESVNEDTLQLLQKIHKEQKSLVETHNKVAEKIIKQNLL 1324
+L+D+ ++H + F PV L DY +IIK PMDL+TI+K L++ Y ++ ED +F NCY YN DI +A+ L+ +F + S+ PQ QV K E + + T Q + ++KS EK+ KQ +
Sbjct: 39 VLKDL----WKHSFSWPFQRPVDAVKLKLPDYYTIIKNPMDLNTIKKRLENKYYVKASECIEDFNTMFSNCYLYNKPGDDIVLMAQALEKLFVQKLSQM-----PQEEQVVGGK---ERIKKGTQQNIAVFSAKEKS----SPNATEKVFKQQAI 177
BLAST of Bromodomain containing 2 vs. UniProt/SwissProt
Match: sp|Q58F21|BRDT_HUMAN (Bromodomain testis-specific protein OS=Homo sapiens OX=9606 GN=BRDT PE=1 SV=4) HSP 1 Score: 161.384 bits (407), Expect = 4.217e-39 Identity = 111/354 (31.36%), Postives = 174/354 (49.15%), Query Frame = 2
Query: 203 TNRLQFIKKKILPQLMRHKYSFPFLHPVDHAALNIPDYPKIIHYPMDFTTVKNRLIKKFYYNADECITDIRLVFQNCYIFNPPEIDLISMTLTLENIFNSKLDKLPSQEXXXXXXXXXXXXXXXXXXXXXXXEPVCDIKKSLRPTTKRLKXXXXXXXXXXXXXXXCSISPDAK-----------SKAKKRKVE------SCYDLSPTPSPSISLKNESLDEIPIKPKLSEEL----KMCSNILRDIS-SNRYRHLNDMFME---------------PVAVRFPNLSDYSSIIKKPMDLSTIRKNLDDGSYKTKNDFSEDVKLIFDNCYDYNGKDSDISKLAKDLQNIFDELFSK 1153
TN+LQ+++K +L L +H +S+PF PVD L +PDY II PMD T+K RL K+Y A ECI D +F NCY++N P D++ M LE +F KL ++P +E + K +I S+ E K S T K K + T+ S ++ A +K KRK + S S SP+ + K+ +L PIK + + + + N+++ + + + RH +++ E PV V L +Y ++K PMDL TI++ +D+ YK F+ DV+L+F NCY YN D ++ +A+ LQ++F+ FSK
Sbjct: 29 TNQLQYLQKVVLKDLWKHSFSWPFQRPVDAVKLQLPDYYTIIKNPMDLNTIKKRLENKYYAKASECIEDFNTMFSNCYLYNKPGDDIVLMAQALEKLFMQKLSQMPQEEQVVGVKERIKKGTQQNIAVSSAKE-----KSSPSATEKVFKQQEIPSVFPKTSISPLNVVQGASVNSSSQTAAQVTKGVKRKADTTTPATSAVKASSEFSPTFTEKSVALP--PIKENMPKNVLPDSQQQYNVVKTVKVTEQLRHCSEILKEMLAKKHFSYAWPFYNPVDVNALGLHNYYDVVKNPMDLGTIKEKMDNQEYKDAYKFAADVRLMFMNCYKYNPPDHEVVTMARMLQDVFETHFSK 375 HSP 2 Score: 106.686 bits (265), Expect = 4.157e-22 Identity = 47/74 (63.51%), Postives = 63/74 (85.14%), Query Frame = 2
Query: 1685 EDCKPMSYDDKRKLSMDINQLPGDKLGRIVQIIQEREPTLRDSNPDEIEIDFEVLHPVTLRELQKFVQSVLSRQ 1906
++ KPM+YD+KR+LS++IN+LPGDKLGR+V IIQ REP+L +SNPDEIEIDFE L TLREL+K+V + L ++
Sbjct: 505 DNAKPMNYDEKRQLSLNINKLPGDKLGRVVHIIQSREPSLSNSNPDEIEIDFETLKASTLRELEKYVSACLRKR 578 HSP 3 Score: 82.4185 bits (202), Expect = 1.415e-14 Identity = 34/100 (34.00%), Postives = 64/100 (64.00%), Query Frame = 2
Query: 230 KILPQLMRHK---YSFPFLHPVDHAALNIPDYPKIIHYPMDFTTVKNRLIKKFYYNADECITDIRLVFQNCYIFNPPEIDLISMTLTLENIFNSKLDKLP 520
+IL +++ K Y++PF +PVD AL + +Y ++ PMD T+K ++ + Y +A + D+RL+F NCY +NPP+ ++++M L+++F + K+P
Sbjct: 278 EILKEMLAKKHFSYAWPFYNPVDVNALGLHNYYDVVKNPMDLGTIKEKMDNQEYKDAYKFAADVRLMFMNCYKYNPPDHEVVTMARMLQDVFETHFSKIP 377 HSP 4 Score: 63.929 bits (154), Expect = 6.440e-9 Identity = 39/110 (35.45%), Postives = 59/110 (53.64%), Query Frame = 2
Query: 863 ILRDISSNRYRH-LNDMFMEPVAVRFPNLSDYSSIIKKPMDLSTIRKNLDDGSYKTKNDFSEDVKLIFDNCYDYNGKDSDISKLAKDLQNIFDELFSKQFNLSKPQPSQV 1189
+L+D+ ++H + F PV L DY +IIK PMDL+TI+K L++ Y ++ ED +F NCY YN DI +A+ L+ +F + S+ PQ QV
Sbjct: 39 VLKDL----WKHSFSWPFQRPVDAVKLQLPDYYTIIKNPMDLNTIKKRLENKYYAKASECIEDFNTMFSNCYLYNKPGDDIVLMAQALEKLFMQKLSQM-----PQEEQV 139
BLAST of Bromodomain containing 2 vs. UniProt/SwissProt
Match: sp|Q5A4W8|BDF1_CANAL (Bromodomain-containing factor 1 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) OX=237561 GN=BDF1 PE=1 SV=1) HSP 1 Score: 125.176 bits (313), Expect = 5.433e-28 Identity = 89/340 (26.18%), Postives = 165/340 (48.53%), Query Frame = 2
Query: 245 LMRHKYSFPFLHPVDHAALNIPDYPKIIHYPMDFTTVKNRLIKKFYYNADECITDIRLVFQNCYIFNPPEIDLISMTLTLENIFNSKLDKLPSQEXXXXXXXXXXXXXXXXXXXXXXXEPVCDIKKSLRPTTKRLKXXXXXXXXXXXXXXXCSISPDAKSKAKKRKVESCYDLSPTPSPSISLKNESLDEIPIKPKLSEELKMCSNILRDISSNRYRHLNDMFMEPVAVRFPNLSDYSSIIKKPMDLSTIRKNLDDGSYKTKNDFSEDVKLIFDNCYDYNGKDSDISKLAKDLQNIFDELFS-KQFNLSKPQPSQVQNSKIKSESVNEDTLQLLQKIHKE 1261
+ R++ + PFLHPVD LN+P Y I PMD +T++ ++ K Y + + + D L+ +NC FN + M ++ F + K+P +E ++ ++ + + PTT + KS + + + S + P K K E Y+ P KN+ K++ EL+ C+ ++++ S ++ + N F+ PV N+ +Y+ I+K+PMDL TI+ L + Y+ +DF +DV+L+F NCY +N + +D++ + L+ +FD+ ++ K PQ S V + + SE ED +++ + + E
Sbjct: 225 VKRNREAVPFLHPVDTVKLNVPFYYNYIPRPMDLSTIERKINLKAYEDVSQVVDDFNLMVKNCKKFNGEAAGISKMATNIQAQFEKLMVKVPPKELPAGTNVAEATSV------------------ATSPTTNKRKSVAESSSSHQHRDSVAAARPKRTIHPPKSK-ELPYETKP--------KNK---------KVAAELRFCNQTIKELMSKKHYNYNFPFLAPVDTVALNIPNYNEIVKQPMDLGTIQSKLANNEYENADDFEKDVRLVFKNCYLFNPEGTDVNMMGHRLEAVFDKKWANKPVPEPTPQNSDVSDREYSSEE--EDNVEISEAMLSE 526 HSP 2 Score: 57.3806 bits (137), Expect = 5.924e-7 Identity = 37/129 (28.68%), Postives = 65/129 (50.39%), Query Frame = 2
Query: 767 PTPSPSISLKNESLDEIPIKPKLSEELKMCSNILRDISSNRYRHLNDMFMEPVAVRFPNLSDYSSIIKKPMDLSTIRKNLDDGSYKTKNDFSEDVKLIFDNCYDYNGKDSDISKLAKDLQNIFDELFSK 1153
P P P + ++ +P P + K N ++ + NR F+ PV N+ Y + I +PMDLSTI + ++ +Y+ + +D L+ NC +NG+ + ISK+A ++Q F++L K
Sbjct: 192 PAPKPP---QEPDMNNLPENPIPQHQAKFVLNTIKAVKRNREAVP---FLHPVDTVKLNVPFYYNYIPRPMDLSTIERKINLKAYEDVSQVVDDFNLMVKNCKKFNGEAAGISKMATNIQAQFEKLMVK 314
BLAST of Bromodomain containing 2 vs. UniProt/SwissProt
Match: sp|O60885|BRD4_HUMAN (Bromodomain-containing protein 4 OS=Homo sapiens OX=9606 GN=BRD4 PE=1 SV=2) HSP 1 Score: 120.168 bits (300), Expect = 4.592e-26 Identity = 59/157 (37.58%), Postives = 88/157 (56.05%), Query Frame = 2
Query: 113 MLVSDDCVEVSQQIDKNVDCSGKPRPANIS------------------TNRLQFIKKKILPQLMRHKYSFPFLHPVDHAALNIPDYPKIIHYPMDFTTVKNRLIKKFYYNADECITDIRLVFQNCYIFNPPEIDLISMTLTLENIFNSKLDKLPSQE 529
+ V D +E SQ +P+PAN + TN+LQ++ + +L L +H++++PF PVD LN+PDY KII PMD T+K RL +Y+NA ECI D +F NCYI+N P D++ M LE +F K+++LP++E
Sbjct: 14 LPVMGDGLETSQM--STTQAQAQPQPANAASTNPPPPETSNPNKPKRQTNQLQYLLRVVLKTLWKHQFAWPFQQPVDAVKLNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLFLQKINELPTEE 168 HSP 2 Score: 113.62 bits (283), Expect = 4.131e-24 Identity = 49/72 (68.06%), Postives = 64/72 (88.89%), Query Frame = 2
Query: 1691 CKPMSYDDKRKLSMDINQLPGDKLGRIVQIIQEREPTLRDSNPDEIEIDFEVLHPVTLRELQKFVQSVLSRQ 1906
CKPMSY++KR+LS+DIN+LPG+KLGR+V IIQ REP+L++SNPDEIEIDFE L P TLREL+++V S L ++
Sbjct: 607 CKPMSYEEKRQLSLDINKLPGEKLGRVVHIIQSREPSLKNSNPDEIEIDFETLKPSTLRELERYVTSCLRKK 678 HSP 3 Score: 101.679 bits (252), Expect = 1.815e-20 Identity = 44/108 (40.74%), Postives = 68/108 (62.96%), Query Frame = 2
Query: 830 KLSEELKMCSNILRDISSNRYRHLNDMFMEPVAVRFPNLSDYSSIIKKPMDLSTIRKNLDDGSYKTKNDFSEDVKLIFDNCYDYNGKDSDISKLAKDLQNIFDELFSK 1153
K+SE+LK CS IL+++ + ++ F +PV V L DY IIK PMD+STI+ L+ Y+ +F DV+L+F NCY YN D ++ +A+ LQ++F+ F+K
Sbjct: 349 KVSEQLKCCSGILKEMFAKKHAAYAWPFYKPVDVEALGLHDYCDIIKHPMDMSTIKSKLEAREYRDAQEFGADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRFAK 456 HSP 4 Score: 89.3521 bits (220), Expect = 1.308e-16 Identity = 36/87 (41.38%), Postives = 59/87 (67.82%), Query Frame = 2
Query: 260 YSFPFLHPVDHAALNIPDYPKIIHYPMDFTTVKNRLIKKFYYNADECITDIRLVFQNCYIFNPPEIDLISMTLTLENIFNSKLDKLP 520
Y++PF PVD AL + DY II +PMD +T+K++L + Y +A E D+RL+F NCY +NPP+ ++++M L+++F + K+P
Sbjct: 372 YAWPFYKPVDVEALGLHDYCDIIKHPMDMSTIKSKLEAREYRDAQEFGADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRFAKMP 458 HSP 5 Score: 67.0106 bits (162), Expect = 8.046e-10 Identity = 35/93 (37.63%), Postives = 52/93 (55.91%), Query Frame = 2
Query: 863 ILRDISSNRYRH-LNDMFMEPV-AVRFPNLSDYSSIIKKPMDLSTIRKNLDDGSYKTKNDFSEDVKLIFDNCYDYNGKDSDISKLAKDLQNIF 1135
+LR + ++H F +PV AV+ NL DY IIK PMD+ TI+K L++ Y + +D +F NCY YN DI +A+ L+ +F
Sbjct: 66 LLRVVLKTLWKHQFAWPFQQPVDAVKL-NLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLF 157
BLAST of Bromodomain containing 2 vs. UniProt/SwissProt
Match: sp|Q9ESU6|BRD4_MOUSE (Bromodomain-containing protein 4 OS=Mus musculus OX=10090 GN=Brd4 PE=1 SV=2) HSP 1 Score: 119.783 bits (299), Expect = 6.082e-26 Identity = 59/157 (37.58%), Postives = 88/157 (56.05%), Query Frame = 2
Query: 113 MLVSDDCVEVSQQIDKNVDCSGKPRPANIS------------------TNRLQFIKKKILPQLMRHKYSFPFLHPVDHAALNIPDYPKIIHYPMDFTTVKNRLIKKFYYNADECITDIRLVFQNCYIFNPPEIDLISMTLTLENIFNSKLDKLPSQE 529
+ V D +E SQ +P+PAN + TN+LQ++ + +L L +H++++PF PVD LN+PDY KII PMD T+K RL +Y+NA ECI D +F NCYI+N P D++ M LE +F K+++LP++E
Sbjct: 14 LPVMGDGLETSQM--STTQAQAQPQPANAASTNPPPPETSNPNKPKRQTNQLQYLLRVVLKTLWKHQFAWPFQQPVDAVKLNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLFLQKINELPTEE 168 HSP 2 Score: 113.62 bits (283), Expect = 4.193e-24 Identity = 49/72 (68.06%), Postives = 64/72 (88.89%), Query Frame = 2
Query: 1691 CKPMSYDDKRKLSMDINQLPGDKLGRIVQIIQEREPTLRDSNPDEIEIDFEVLHPVTLRELQKFVQSVLSRQ 1906
CKPMSY++KR+LS+DIN+LPG+KLGR+V IIQ REP+L++SNPDEIEIDFE L P TLREL+++V S L ++
Sbjct: 608 CKPMSYEEKRQLSLDINKLPGEKLGRVVHIIQSREPSLKNSNPDEIEIDFETLKPSTLRELERYVTSCLRKK 679 HSP 3 Score: 102.449 bits (254), Expect = 1.160e-20 Identity = 44/108 (40.74%), Postives = 68/108 (62.96%), Query Frame = 2
Query: 830 KLSEELKMCSNILRDISSNRYRHLNDMFMEPVAVRFPNLSDYSSIIKKPMDLSTIRKNLDDGSYKTKNDFSEDVKLIFDNCYDYNGKDSDISKLAKDLQNIFDELFSK 1153
K+SE+LK CS IL+++ + ++ F +PV V L DY IIK PMD+STI+ L+ Y+ +F DV+L+F NCY YN D ++ +A+ LQ++F+ F+K
Sbjct: 350 KISEQLKCCSGILKEMFAKKHAAYAWPFYKPVDVEALGLHDYCDIIKHPMDMSTIKSKLESREYRDAQEFGADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRFAK 457 HSP 4 Score: 88.9669 bits (219), Expect = 1.691e-16 Identity = 36/87 (41.38%), Postives = 59/87 (67.82%), Query Frame = 2
Query: 260 YSFPFLHPVDHAALNIPDYPKIIHYPMDFTTVKNRLIKKFYYNADECITDIRLVFQNCYIFNPPEIDLISMTLTLENIFNSKLDKLP 520
Y++PF PVD AL + DY II +PMD +T+K++L + Y +A E D+RL+F NCY +NPP+ ++++M L+++F + K+P
Sbjct: 373 YAWPFYKPVDVEALGLHDYCDIIKHPMDMSTIKSKLESREYRDAQEFGADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRFAKMP 459 HSP 5 Score: 67.3958 bits (163), Expect = 6.837e-10 Identity = 35/93 (37.63%), Postives = 52/93 (55.91%), Query Frame = 2
Query: 863 ILRDISSNRYRH-LNDMFMEPV-AVRFPNLSDYSSIIKKPMDLSTIRKNLDDGSYKTKNDFSEDVKLIFDNCYDYNGKDSDISKLAKDLQNIF 1135
+LR + ++H F +PV AV+ NL DY IIK PMD+ TI+K L++ Y + +D +F NCY YN DI +A+ L+ +F
Sbjct: 66 LLRVVLKTLWKHQFAWPFQQPVDAVKL-NLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLF 157
BLAST of Bromodomain containing 2 vs. TrEMBL
Match: A0A5K3EI34 (Uncharacterized protein OS=Mesocestoides corti OX=53468 PE=4 SV=1) HSP 1 Score: 332.798 bits (852), Expect = 3.301e-98 Identity = 212/597 (35.51%), Postives = 323/597 (54.10%), Query Frame = 2
Query: 179 KPRPANISTNRLQFIKKKILPQLMRHKYSFPFLHPVDHAALNIPDYPKIIHYPMDFTTVKNRLIKKFYYNADECITDIRLVFQNCYIFNPPEIDLISMTLTLENIFNSKLD-------KLPSQEXXXXXXXXXXXXXXXXXXXXXXXEPVCDIKKS--LRPTTKRLKXXXXXXXXXXXXXXXCSISPDAKSKAKKRKVE--SCYDLSPTPSPSISLKNESLDE--------IPIKPKLSEELKMCSNILRDISSNRYRHLNDMFMEPVAVRFPNLSDYSSIIKKPMDLSTIRKNLDDGSYKTKNDFSEDVKLIFDNCYDYNGKDSDISKLAKDLQNIFDELFSKQFNLSKPQPSQVQNSKIKSESVNEDTLQLLQKIHKEQKSLVETHNKVAEKIIKQNLLIRELSSTLKIPFEFDLSLINVNSSAVFAXXXXXXXXXXXXXXPIMAKTNGVL---NNHVMVSDTMSKSARQKKPTQESSSNSVPAESNRTETNVASSMPATLRMPCNESYQNTELPSKTNRVTEDCKPMSYDDKRKLSMDINQLPGDKLGRIVQIIQEREPTLRDSNPDEIEIDFEVLHPVTLRELQKFVQSVLSR 1903
K R A ++TN+L FIK+ ++ + + K ++PFL PVDH LN+PDYPKI+ +PMD T+K RL KFY A EC+ D+ +F+NCYIFN P D+++M + LE + KL +L SQ+ + S + S+S + S V D+ S + P+T + ++ ++ K KRK E S D+S TP + + L + + + +L E LK CSN+L+DISS RYRHLN +F+ PV V LSDY II PMDLST+R LD G Y+ KN+F+ D++L+F+NCY YNG+ SD++ + + LQ IF+E F+K + + + L+Q + K+ + +V +NK E++ K + I + S L P D + I + F+ +G L ++HV + + ++K S N+VPA+ + + ++MP +E + + + +PM+YD+KR+LS+DIN+LPG+KLGR+VQIIQ+REP+ RD NPDEIEIDFE L TLREL+++V+SVL +
Sbjct: 7 KSRAAKVNTNQLDFIKRHVISVIAKDKLAWPFLKPVDHQKLNLPDYPKIVKHPMDLGTIKQRLNLKFYRRASECLDDLFTMFRNCYIFNKPGDDVVAMAMKLERVARDKLQNMPFPEVELSSQKPNTSQVPPTSNISSDSNLSMSIVNNVEDLNGSSLVPPST---------PSGVALSSHPGPLTSTLNKKLPKRKPEPPSLDDISSTPHSTDDSRERRLAKKTKVEERVVGKRVRLCESLKQCSNLLKDISSARYRHLNQLFLHPVDVEGLGLSDYHDIITHPMDLSTVRSKLDSGIYQNKNEFAADLRLMFNNCYKYNGETSDVASVGRTLQGIFEEQFAK-----------ILDDDGDGSVDSRSCDALIQTVLKDHQRIVAQYNKFGEELQKISSSINTILSILNHP--ADQTPIKLPKKGQFS-----------------VHNSGALSGYDDHVNRKTSKASQKAKRKMPNASYQNAVPAQVSGGIPGIQNAMPVAT-YGVDEGFVS----------DANVRPMTYDEKRQLSLDINKLPGEKLGRVVQIIQQREPSHRDCNPDEIEIDFETLQHSTLRELERYVKSVLQK 553
BLAST of Bromodomain containing 2 vs. TrEMBL
Match: A0A4S2M8C2 (Uncharacterized protein OS=Opisthorchis felineus OX=147828 GN=CRM22_003256 PE=4 SV=1) HSP 1 Score: 332.798 bits (852), Expect = 7.471e-98 Identity = 240/672 (35.71%), Postives = 361/672 (53.72%), Query Frame = 2
Query: 173 SGKPRPANISTNRLQFIKKKILPQLMRHKYSFPFLHPVDHAALNIPDYPKIIHYPMDFTTVKNRLIKKFYYNADECITDIRLVFQNCYIFNPPEIDLISMTLTLENIFNSKLDKLPSQEXXXXXXXXXXXXXXXXXXXXXXXEPVCDIKKSLRP--------TTKRLKXXXXXXXXXXXXXXXCSISPDAKSKAKKRKVESCYD-LSPTPSPSISLKNESLDEIPIK-PK-------------LSEELKMCSNILRDISSNRYRHLNDMFMEPVAVRFPNLSDYSSIIKKPMDLSTIRKNLDDGSYKTKNDFSEDVKLIFDNCYDYNGKDSDISKLAKDLQNIFDELFSKQFNLSK---PQPSQVQNSKIKSESVNEDTLQLLQKIHKEQKSLVETHNKVAEKIIKQ----NLLIRELSSTLKIPFEFDLSLINVNSSAVFAXXXXXXXXXXXXXXPIMAKT--NGVLNNHVMVSDTMSKSARQKKPTQESSSNSVPAESNRTETNVASSMPATLRMPCNESYQNTELPSKTNRVTEDCKPMSYDDKRKLSMDINQLPGDKLGRIVQIIQEREPTLRDSNPDEIEIDFEVLHPVTLRELQKFVQSVLSRQXXXXXXXXXXXXXGQAGQISEGVITTNTGT---EDLASKTKE-ESRKDSFEDYP-NIQGFNN 2077
S K P+ I+TN+L++IKK+++ +L++ K +PF PVDH LN+PDYP+I+ +PMD T+K RL KFY+++ EC+ D+ +F+NCYIFN P D+++M + LE + +L +PS E +I + K T +PV ++ + P + L S +E + + S S KA K+K+E+ D L TP SL + S D IK PK LSE LK CSNIL+DISS RYR LN +F++PV L DY ++KK MDLST++ L+ G Y +K +F++D++L+F+NCY YNG+DSD++K+ K LQ IF+E F+K + P P + S++++ QL+Q KE + L + E++ + N +I L++ K + +NS + ++ S P+ ++ +GV + S + SK RQ Q SS+ ++ A TN +T+ Y E S+ N +PM+YD+KR+LS+DIN+LPG+KLGR+VQIIQ+REP+ RD NPDEIEIDFE L TLREL+K+V+SVL + +G + +G T G E + KT+E ESR P + GF+N
Sbjct: 19 SSKSHPSKITTNQLEYIKKEVVGRLLKEKIVWPFTRPVDHERLNLPDYPRIVKHPMDLGTIKQRLNLKFYHSSSECLDDLFTMFRNCYIFNKPGDDVVAMAMKLEQLARERLKSMPSPETEICPQKNSKST-----------KPVSSLRSTDDPPAPLPELNHVEGLNGTSLSSEPSGPAIRSSSSS--TGKKASKKKMENLLDDLPQTPH---SLDDPSRDRRQIKKPKRDYEERSVAKRLRLSEALKACSNILKDISSQRYRDLNHLFLKPVDAEAMGLHDYHDVVKKAMDLSTVKTKLESGQYHSKYEFADDIRLMFNNCYKYNGEDSDVAKVGKLLQAIFEESFAKVPDDESEIVPSPDR---------SIDQNLYQLIQNAIKEHQRLTVQFQRCNEELQRSAANLNSIISTLNTQAKRASANTGQVPQLNSVPL-------GQSAGASVRPVSNESFDDGVSSRKGRQSQSKSK-YRQTTALQTSSAPTLNA------TNATGHPQSTV-----HGYATDEEMSENN-----VRPMTYDEKRQLSIDINKLPGEKLGRVVQIIQQREPSHRDCNPDEIEIDFETLQHTTLRELEKYVKSVLQK-----------AKSGSRKYVKKGPNTATPGKSREECMKEKTEEIESRLREMRGLPSSASGFHN 630
BLAST of Bromodomain containing 2 vs. TrEMBL
Match: W6V1W1 (Bromodomain-containing protein 2 OS=Echinococcus granulosus OX=6210 GN=EGR_05210 PE=4 SV=1) HSP 1 Score: 329.331 bits (843), Expect = 5.144e-97 Identity = 209/601 (34.78%), Postives = 322/601 (53.58%), Query Frame = 2
Query: 164 VDCSG-KPRPANISTNRLQFIKKKILPQLMRHKYSFPFLHPVDHAALNIPDYPKIIHYPMDFTTVKNRLIKKFYYNADECITDIRLVFQNCYIFNPPEIDLISMTLTLENIFNSKLDKLPSQEXXXXXXXXXXXXXXXXXXXXXXXEPVCDIKKSLRPTTKRLKXXX----XXXXXXXXXXXXCSISPDAKSKAKKRKVESCYDLSPTPSPSISLKNESLDE-----IPIKPK-----------LSEELKMCSNILRDISSNRYRHLNDMFMEPVAVRFPNLSDYSSIIKKPMDLSTIRKNLDDGSYKTKNDFSEDVKLIFDNCYDYNGKDSDISKLAKDLQNIFDELFSKQFNLSKPQPSQVQNSKIKSESVNEDTLQLLQKIHKEQKSLVETHNKVAEKIIKQNLLIRELSSTLKIPFEFDLSLINVNSSAVFAXXXXXXXXXXXXXXPIMAKTNGVLNNHVMVSDTMSKSARQKKPTQESSSNSVPAESNRTETNVASSMPATLRMPCNESYQNTELPSKTNRVTEDCKPMSYDDKRKLSMDINQLPGDKLGRIVQIIQEREPTLRDSNPDEIEIDFEVLHPVTLRELQKFVQSVLSR 1903
+D +G K R A ++TN+L+FIK+ ++ + + K ++PFL PVDH LN+PDYPKII +PMD T+K RL KFY + EC+ D+ +F+NCYIFN P D+++M + LE + KL LP E ++ S + + N + + S+ T+ L +S + ++ KA KRK +S D+ TP S+DE + KPK LSE LK CSN+L+D+ + RYR+ N +F++PV V L DY II PMDLSTIR LD G Y+ KN+F+ D++L+FDNCY YNG+ SD+S L + LQ IF+E F+K + V ++ ++Q + K+ + +V +NK E++ K + + + + L P D + + + FA + ++HV ++ ++K + N+V A++ T + ++MP +E + + + +PM+YD+KR+LS+DIN+LPG+KLGR+VQIIQ+REP+ RD NPDEIEIDFE L TLREL+++V+SVL +
Sbjct: 1 MDATGVKSRVAKVNTNQLEFIKRNVIAVIAKDKLAWPFLKPVDHHKLNLPDYPKIIKHPMDLGTIKQRLNLKFYRHGAECLRDLFTMFRNCYIFNKPGDDVVAMAMKLERVAREKLQNLPYPEVELISQKLSTSHTAPTSNLSTD----SNFSMSILNNTEELNGSSLVPPTTPSGVALQQHQGPLTSSVNKKALKRKPDSLDDIPSTP--------HSMDESRERRVSKKPKMEERVIGKRVRLSESLKQCSNLLKDLCAARYRY-NQLFLKPVDVERLGLHDYHDIITHPMDLSTIRTKLDSGVYQNKNEFAADMRLMFDNCYKYNGEKSDVSDLGRALQGIFEENFAKILDDDVDGVHTVDPRSCEA---------MIQAVIKDHQRIVAQYNKFGEELQKLSSNLTTILTVLNHP--ADQAGVKMLKKGQFAVHNFSALSS--------------FDDHVGRKAKTTQKTKRKSQNPSTYQNAVSAQAASTVPGMPNAMPVA-PYGVDEGFVS----------DANVRPMTYDEKRQLSLDINKLPGEKLGRVVQIIQQREPSHRDCNPDEIEIDFETLQASTLRELERYVKSVLQK 552
BLAST of Bromodomain containing 2 vs. TrEMBL
Match: A0A4S2M714 (Uncharacterized protein OS=Opisthorchis felineus OX=147828 GN=CRM22_003256 PE=4 SV=1) HSP 1 Score: 333.954 bits (855), Expect = 1.081e-95 Identity = 240/672 (35.71%), Postives = 361/672 (53.72%), Query Frame = 2
Query: 173 SGKPRPANISTNRLQFIKKKILPQLMRHKYSFPFLHPVDHAALNIPDYPKIIHYPMDFTTVKNRLIKKFYYNADECITDIRLVFQNCYIFNPPEIDLISMTLTLENIFNSKLDKLPSQEXXXXXXXXXXXXXXXXXXXXXXXEPVCDIKKSLRPTT--------KRLKXXXXXXXXXXXXXXXCSISPDAKSKAKKRKVESCYD-LSPTPSPSISLKNESLDEIPIK-PK-------------LSEELKMCSNILRDISSNRYRHLNDMFMEPVAVRFPNLSDYSSIIKKPMDLSTIRKNLDDGSYKTKNDFSEDVKLIFDNCYDYNGKDSDISKLAKDLQNIFDELFSKQFNLSK---PQPSQVQNSKIKSESVNEDTLQLLQKIHKEQKSLVETHNKVAEKIIKQ----NLLIRELSSTLKIPFEFDLSLINVNSSAVFAXXXXXXXXXXXXXXPIMAKT--NGVLNNHVMVSDTMSKSARQKKPTQESSSNSVPAESNRTETNVASSMPATLRMPCNESYQNTELPSKTNRVTEDCKPMSYDDKRKLSMDINQLPGDKLGRIVQIIQEREPTLRDSNPDEIEIDFEVLHPVTLRELQKFVQSVLSRQXXXXXXXXXXXXXGQAGQISEGVITTNTGT---EDLASKTKE-ESRKDSFEDYP-NIQGFNN 2077
S K P+ I+TN+L++IKK+++ +L++ K +PF PVDH LN+PDYP+I+ +PMD T+K RL KFY+++ EC+ D+ +F+NCYIFN P D+++M + LE + +L +PS E +I + K T +PV ++ + P + L S +E + + S S KA K+K+E+ D L TP SL + S D IK PK LSE LK CSNIL+DISS RYR LN +F++PV L DY ++KK MDLST++ L+ G Y +K +F++D++L+F+NCY YNG+DSD++K+ K LQ IF+E F+K + P P + S++++ QL+Q KE + L + E++ + N +I L++ K + +NS + ++ S P+ ++ +GV + S + SK RQ Q SS+ ++ A TN +T+ Y E S+ N +PM+YD+KR+LS+DIN+LPG+KLGR+VQIIQ+REP+ RD NPDEIEIDFE L TLREL+K+V+SVL + +G + +G T G E + KT+E ESR P + GF+N
Sbjct: 19 SSKSHPSKITTNQLEYIKKEVVGRLLKEKIVWPFTRPVDHERLNLPDYPRIVKHPMDLGTIKQRLNLKFYHSSSECLDDLFTMFRNCYIFNKPGDDVVAMAMKLEQLARERLKSMPSPETEICPQKNSKST-----------KPVSSLRSTDDPPAPLPELNHVEGLNGTSLSSEPSGPAIRSSSSS--TGKKASKKKMENLLDDLPQTPH---SLDDPSRDRRQIKKPKRDYEERSVAKRLRLSEALKACSNILKDISSQRYRDLNHLFLKPVDAEAMGLHDYHDVVKKAMDLSTVKTKLESGQYHSKYEFADDIRLMFNNCYKYNGEDSDVAKVGKLLQAIFEESFAKVPDDESEIVPSPDR---------SIDQNLYQLIQNAIKEHQRLTVQFQRCNEELQRSAANLNSIISTLNTQAKRASANTGQVPQLNSVPL-------GQSAGASVRPVSNESFDDGVSSRKGRQSQSKSK-YRQTTALQTSSAPTLNA------TNATGHPQSTV-----HGYATDEEMSENN-----VRPMTYDEKRQLSIDINKLPGEKLGRVVQIIQQREPSHRDCNPDEIEIDFETLQHTTLRELEKYVKSVLQK-----------AKSGSRKYVKKGPNTATPGKSREECMKEKTEEIESRLREMRGLPSSASGFHN 630
BLAST of Bromodomain containing 2 vs. TrEMBL
Match: A0A068X388 (Bromodomain containing 2 OS=Echinococcus granulosus OX=6210 GN=EgrG_000332900 PE=4 SV=1) HSP 1 Score: 333.569 bits (854), Expect = 5.539e-95 Identity = 210/601 (34.94%), Postives = 322/601 (53.58%), Query Frame = 2
Query: 164 VDCSG-KPRPANISTNRLQFIKKKILPQLMRHKYSFPFLHPVDHAALNIPDYPKIIHYPMDFTTVKNRLIKKFYYNADECITDIRLVFQNCYIFNPPEIDLISMTLTLENIFNSKLDKLPSQEXXXXXXXXXXXXXXXXXXXXXXXEPVCDIKKSLRPTTKRLKXXX----XXXXXXXXXXXXCSISPDAKSKAKKRKVESCYDLSPTPSPSISLKNESLDE-----IPIKPK-----------LSEELKMCSNILRDISSNRYRHLNDMFMEPVAVRFPNLSDYSSIIKKPMDLSTIRKNLDDGSYKTKNDFSEDVKLIFDNCYDYNGKDSDISKLAKDLQNIFDELFSKQFNLSKPQPSQVQNSKIKSESVNEDTLQLLQKIHKEQKSLVETHNKVAEKIIKQNLLIRELSSTLKIPFEFDLSLINVNSSAVFAXXXXXXXXXXXXXXPIMAKTNGVLNNHVMVSDTMSKSARQKKPTQESSSNSVPAESNRTETNVASSMPATLRMPCNESYQNTELPSKTNRVTEDCKPMSYDDKRKLSMDINQLPGDKLGRIVQIIQEREPTLRDSNPDEIEIDFEVLHPVTLRELQKFVQSVLSR 1903
+D +G K R A ++TN+L+FIK+ ++ + + K ++PFL PVDH LN+PDYPKII +PMD T+K RL KFY + EC+ D+ +F+NCYIFN P D+++M + LE + KL LP E ++ S + + N + S + S+ T+ L +S + ++ KA KRK +S D+ TP S+DE + KPK LSE LK CSN+L+D+ + RYR N +F++PV V L DY II PMDLSTIR LD G Y+ KN+F+ D++L+FDNCY YNG+ SD+S L + LQ IF+E F+K + V ++ ++Q + K+ + +V +NK E++ K + + + + L P D + + + FA + ++HV ++ ++K + N+V A++ T + ++MP +E + + + +PM+YD+KR+LS+DIN+LPG+KLGR+VQIIQ+REP+ RD NPDEIEIDFE L TLREL+++V+SVL +
Sbjct: 1 MDATGVKSRVAKVNTNQLEFIKRNVIAVIAKDKLAWPFLKPVDHHKLNLPDYPKIIKHPMDLGTIKQRLNLKFYRHGAECLRDLFTMFRNCYIFNKPGDDVVAMAMKLERVAREKLQNLPYPEVELISQKLSTSHTAPTSNLSTDS----NFSMSILNNTEELNGSSLVPPTTPSGVALQQHQGPLTSSVNKKALKRKPDSLDDIPSTP--------HSMDESRERRVSKKPKMEERVIGKRVRLSESLKQCSNLLKDLCAARYRQYNQLFLKPVDVERLGLHDYHDIITHPMDLSTIRTKLDSGVYQNKNEFAADMRLMFDNCYKYNGEKSDVSDLGRALQGIFEENFAKILDDDVDGVHTVDPRSCEA---------MIQAVIKDHQRIVAQYNKFGEELQKLSSNLTTILTVLNHP--ADQAGVKMLKKGQFAVHNFSALSS--------------FDDHVGRKAKTTQKTKRKSQNPSTYQNAVSAQAASTVPGMPNAMPVA-PYGVDEGFVS----------DANVRPMTYDEKRQLSLDINKLPGEKLGRVVQIIQQREPSHRDCNPDEIEIDFETLQASTLRELERYVKSVLQK 553
BLAST of Bromodomain containing 2 vs. Ensembl Cavefish
Match: ENSAMXT00000057848.1 (pep primary_assembly:Astyanax_mexicanus-2.0:12:831065:839047:1 gene:ENSAMXG00000012049.2 transcript:ENSAMXT00000057848.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 113.235 bits (282), Expect = 1.219e-26 Identity = 52/114 (45.61%), Postives = 74/114 (64.91%), Query Frame = 2
Query: 188 PANISTNRLQFIKKKILPQLMRHKYSFPFLHPVDHAALNIPDYPKIIHYPMDFTTVKNRLIKKFYYNADECITDIRLVFQNCYIFNPPEIDLISMTLTLENIFNSKLDKLPSQE 529
PA + TN+LQ++ K +L L +H++S+PF PVD L +PDY KII PMD T+K RL ++Y NA ECI D +F NCYI+N P D++ M LE +F K+ ++P +E
Sbjct: 44 PARM-TNQLQYLLKVVLKTLWKHQFSWPFQAPVDAVKLRLPDYYKIIKCPMDMGTIKKRLENRYYRNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKMFLQKISEMPQEE 156 HSP 2 Score: 58.9214 bits (141), Expect = 9.532e-9 Identity = 33/93 (35.48%), Postives = 52/93 (55.91%), Query Frame = 2
Query: 863 ILRDISSNRYRH-LNDMFMEPV-AVRFPNLSDYSSIIKKPMDLSTIRKNLDDGSYKTKNDFSEDVKLIFDNCYDYNGKDSDISKLAKDLQNIF 1135
+L+ + ++H + F PV AV+ L DY IIK PMD+ TI+K L++ Y+ + +D +F NCY YN DI +A+ L+ +F
Sbjct: 54 LLKVVLKTLWKHQFSWPFQAPVDAVKL-RLPDYYKIIKCPMDMGTIKKRLENRYYRNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKMF 145
BLAST of Bromodomain containing 2 vs. Ensembl Cavefish
Match: BRD3 (bromodomain-containing protein 3-like [Source:NCBI gene;Acc:103046549]) HSP 1 Score: 115.931 bits (289), Expect = 4.010e-26 Identity = 51/74 (68.92%), Postives = 65/74 (87.84%), Query Frame = 2
Query: 1685 EDCKPMSYDDKRKLSMDINQLPGDKLGRIVQIIQEREPTLRDSNPDEIEIDFEVLHPVTLRELQKFVQSVLSRQ 1906
E+ PMSYD+KR+LS+DIN+LPG+KLGR+V IIQ REP+LRDSNPDEIEIDFE L P TLREL+++V+S L ++
Sbjct: 553 EEALPMSYDEKRQLSLDINRLPGEKLGRVVHIIQSREPSLRDSNPDEIEIDFETLKPSTLRELERYVKSCLQKK 626 HSP 2 Score: 113.235 bits (282), Expect = 3.104e-25 Identity = 46/109 (42.20%), Postives = 71/109 (65.14%), Query Frame = 2
Query: 203 TNRLQFIKKKILPQLMRHKYSFPFLHPVDHAALNIPDYPKIIHYPMDFTTVKNRLIKKFYYNADECITDIRLVFQNCYIFNPPEIDLISMTLTLENIFNSKLDKLPSQE 529
TN+LQ+++ ++ L RH++++PF PVD L++PDY K+I PMD T+K RL +Y+ A EC+ D +F NCYI+N P D++ M LE IF K+ ++P +E
Sbjct: 32 TNQLQYMQNVVVKTLWRHQFAWPFYTPVDAIKLSLPDYHKVIKNPMDMGTIKKRLENNYYWTAGECMQDFNTMFTNCYIYNKPTDDIVLMAQALEKIFLQKVAQMPQEE 140 HSP 3 Score: 100.138 bits (248), Expect = 3.694e-21 Identity = 48/119 (40.34%), Postives = 71/119 (59.66%), Query Frame = 2
Query: 797 NESLDEIPIKPKLSEELKMCSNILRDISSNRYRHLNDMFMEPVAVRFPNLSDYSSIIKKPMDLSTIRKNLDDGSYKTKNDFSEDVKLIFDNCYDYNGKDSDISKLAKDLQNIFDELFSK 1153
NE L + K KLS+ LK C IL+++ S ++ F +PV L DY IIK+PMDLST++K +D Y F+ DV+L+F NCY YN D ++ +A+ LQ++F+ F+K
Sbjct: 280 NELLQQGNKKGKLSDHLKHCDTILKEMLSKKHAAYAWPFYKPVDAEALELHDYHEIIKQPMDLSTVKKKMDGREYPDAQSFAADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRFAK 398 HSP 4 Score: 88.5817 bits (218), Expect = 1.447e-17 Identity = 38/101 (37.62%), Postives = 64/101 (63.37%), Query Frame = 2
Query: 233 ILPQLMRHK---YSFPFLHPVDHAALNIPDYPKIIHYPMDFTTVKNRLIKKFYYNADECITDIRLVFQNCYIFNPPEIDLISMTLTLENIFNSKLDKLPSQ 526
IL +++ K Y++PF PVD AL + DY +II PMD +TVK ++ + Y +A D+RL+F NCY +NPP+ ++++M L+++F + K+P +
Sbjct: 302 ILKEMLSKKHAAYAWPFYKPVDAEALELHDYHEIIKQPMDLSTVKKKMDGREYPDAQSFAADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRFAKMPDE 402 HSP 5 Score: 63.929 bits (154), Expect = 6.336e-10 Identity = 33/84 (39.29%), Postives = 48/84 (57.14%), Query Frame = 2
Query: 890 YRH-LNDMFMEPV-AVRFPNLSDYSSIIKKPMDLSTIRKNLDDGSYKTKNDFSEDVKLIFDNCYDYNGKDSDISKLAKDLQNIF 1135
+RH F PV A++ +L DY +IK PMD+ TI+K L++ Y T + +D +F NCY YN DI +A+ L+ IF
Sbjct: 47 WRHQFAWPFYTPVDAIKL-SLPDYHKVIKNPMDMGTIKKRLENNYYWTAGECMQDFNTMFTNCYIYNKPTDDIVLMAQALEKIF 129
BLAST of Bromodomain containing 2 vs. Ensembl Cavefish
Match: BRD3 (bromodomain-containing protein 3-like [Source:NCBI gene;Acc:103046549]) HSP 1 Score: 115.931 bits (289), Expect = 4.144e-26 Identity = 51/74 (68.92%), Postives = 65/74 (87.84%), Query Frame = 2
Query: 1685 EDCKPMSYDDKRKLSMDINQLPGDKLGRIVQIIQEREPTLRDSNPDEIEIDFEVLHPVTLRELQKFVQSVLSRQ 1906
E+ PMSYD+KR+LS+DIN+LPG+KLGR+V IIQ REP+LRDSNPDEIEIDFE L P TLREL+++V+S L ++
Sbjct: 576 EEALPMSYDEKRQLSLDINRLPGEKLGRVVHIIQSREPSLRDSNPDEIEIDFETLKPSTLRELERYVKSCLQKK 649 HSP 2 Score: 112.849 bits (281), Expect = 4.077e-25 Identity = 46/109 (42.20%), Postives = 71/109 (65.14%), Query Frame = 2
Query: 203 TNRLQFIKKKILPQLMRHKYSFPFLHPVDHAALNIPDYPKIIHYPMDFTTVKNRLIKKFYYNADECITDIRLVFQNCYIFNPPEIDLISMTLTLENIFNSKLDKLPSQE 529
TN+LQ+++ ++ L RH++++PF PVD L++PDY K+I PMD T+K RL +Y+ A EC+ D +F NCYI+N P D++ M LE IF K+ ++P +E
Sbjct: 32 TNQLQYMQNVVVKTLWRHQFAWPFYTPVDAIKLSLPDYHKVIKNPMDMGTIKKRLENNYYWTAGECMQDFNTMFTNCYIYNKPTDDIVLMAQALEKIFLQKVAQMPQEE 140 HSP 3 Score: 100.138 bits (248), Expect = 3.798e-21 Identity = 48/119 (40.34%), Postives = 71/119 (59.66%), Query Frame = 2
Query: 797 NESLDEIPIKPKLSEELKMCSNILRDISSNRYRHLNDMFMEPVAVRFPNLSDYSSIIKKPMDLSTIRKNLDDGSYKTKNDFSEDVKLIFDNCYDYNGKDSDISKLAKDLQNIFDELFSK 1153
NE L + K KLS+ LK C IL+++ S ++ F +PV L DY IIK+PMDLST++K +D Y F+ DV+L+F NCY YN D ++ +A+ LQ++F+ F+K
Sbjct: 280 NELLQQGNKKGKLSDHLKHCDTILKEMLSKKHAAYAWPFYKPVDAEALELHDYHEIIKQPMDLSTVKKKMDGREYPDAQSFAADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRFAK 398 HSP 4 Score: 88.1965 bits (217), Expect = 2.016e-17 Identity = 38/101 (37.62%), Postives = 64/101 (63.37%), Query Frame = 2
Query: 233 ILPQLMRHK---YSFPFLHPVDHAALNIPDYPKIIHYPMDFTTVKNRLIKKFYYNADECITDIRLVFQNCYIFNPPEIDLISMTLTLENIFNSKLDKLPSQ 526
IL +++ K Y++PF PVD AL + DY +II PMD +TVK ++ + Y +A D+RL+F NCY +NPP+ ++++M L+++F + K+P +
Sbjct: 302 ILKEMLSKKHAAYAWPFYKPVDAEALELHDYHEIIKQPMDLSTVKKKMDGREYPDAQSFAADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRFAKMPDE 402 HSP 5 Score: 63.929 bits (154), Expect = 6.622e-10 Identity = 33/84 (39.29%), Postives = 48/84 (57.14%), Query Frame = 2
Query: 890 YRH-LNDMFMEPV-AVRFPNLSDYSSIIKKPMDLSTIRKNLDDGSYKTKNDFSEDVKLIFDNCYDYNGKDSDISKLAKDLQNIF 1135
+RH F PV A++ +L DY +IK PMD+ TI+K L++ Y T + +D +F NCY YN DI +A+ L+ IF
Sbjct: 47 WRHQFAWPFYTPVDAIKL-SLPDYHKVIKNPMDMGTIKKRLENNYYWTAGECMQDFNTMFTNCYIYNKPTDDIVLMAQALEKIF 129
BLAST of Bromodomain containing 2 vs. Ensembl Cavefish
Match: ENSAMXT00000012387.2 (pep primary_assembly:Astyanax_mexicanus-2.0:12:832056:842867:1 gene:ENSAMXG00000012049.2 transcript:ENSAMXT00000012387.2 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 114.775 bits (286), Expect = 4.254e-26 Identity = 57/139 (41.01%), Postives = 83/139 (59.71%), Query Frame = 2
Query: 122 SDDCVEVSQQIDKNV---DCSGKPRPANISTNRLQFIKKKILPQLMRHKYSFPFLHPVDHAALNIPDYPKIIHYPMDFTTVKNRLIKKFYYNADECITDIRLVFQNCYIFNPPEIDLISMTLTLENIFNSKLDKLPSQE 529
S D V + + KN + + PA + TN+LQ++ K +L L +H++S+PF PVD L +PDY KII PMD T+K RL ++Y NA ECI D +F NCYI+N P D++ M LE +F K+ ++P +E
Sbjct: 1 SSDWVAPATPLSKNPLVPETTNHTHPARM-TNQLQYLLKVVLKTLWKHQFSWPFQAPVDAVKLRLPDYYKIIKCPMDMGTIKKRLENRYYRNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKMFLQKISEMPQEE 138 HSP 2 Score: 109.383 bits (272), Expect = 2.392e-24 Identity = 52/84 (61.90%), Postives = 66/84 (78.57%), Query Frame = 2
Query: 1655 ELPSKTNRVTEDCKPMSYDDKRKLSMDINQLPGDKLGRIVQIIQEREPTLRDSNPDEIEIDFEVLHPVTLRELQKFVQSVLSRQ 1906
EL +T KPMS ++KR+LS+DIN+LPG+KLGR+V IIQ REPTL++SNPDEIEIDFE L P TLREL+++V S L R+
Sbjct: 431 ELEVETGSQGTSGKPMSLEEKRQLSLDINRLPGNKLGRVVHIIQLREPTLKNSNPDEIEIDFEALKPSTLRELERYVSSCLKRK 514 HSP 3 Score: 75.8702 bits (185), Expect = 9.905e-14 Identity = 35/90 (38.89%), Postives = 55/90 (61.11%), Query Frame = 2
Query: 227 KKILPQLMRHK---YSFPFLHPVDHAALNIPDYPKIIHYPMDFTTVKNRLIKKFYYNADECITDIRLVFQNCYIFNPPEIDLISMTLTLE 487
+ +L ++M K Y++PF PVD AL + DY II + MD +T+K +L + Y +A D+RL+F NCY +NPP+ D++ M L+
Sbjct: 282 RGLLKEMMAKKHAGYAWPFYRPVDSNALGLHDYHDIIKHSMDLSTIKVKLENRQYPDAQAFAADVRLMFSNCYKYNPPDHDVVGMARKLQ 371 HSP 4 Score: 74.7146 bits (182), Expect = 2.089e-13 Identity = 35/95 (36.84%), Postives = 52/95 (54.74%), Query Frame = 2
Query: 842 ELKMCSNILRDISSNRYRHLNDMFMEPVAVRFPNLSDYSSIIKKPMDLSTIRKNLDDGSYKTKNDFSEDVKLIFDNCYDYNGKDSDISKLAKDLQ 1126
+L C +L+++ + ++ F PV L DY IIK MDLSTI+ L++ Y F+ DV+L+F NCY YN D D+ +A+ LQ
Sbjct: 277 QLHHCRGLLKEMMAKKHAGYAWPFYRPVDSNALGLHDYHDIIKHSMDLSTIKVKLENRQYPDAQAFAADVRLMFSNCYKYNPPDHDVVGMARKLQ 371 HSP 5 Score: 60.077 bits (144), Expect = 8.613e-9 Identity = 33/93 (35.48%), Postives = 52/93 (55.91%), Query Frame = 2
Query: 863 ILRDISSNRYRH-LNDMFMEPV-AVRFPNLSDYSSIIKKPMDLSTIRKNLDDGSYKTKNDFSEDVKLIFDNCYDYNGKDSDISKLAKDLQNIF 1135
+L+ + ++H + F PV AV+ L DY IIK PMD+ TI+K L++ Y+ + +D +F NCY YN DI +A+ L+ +F
Sbjct: 36 LLKVVLKTLWKHQFSWPFQAPVDAVKL-RLPDYYKIIKCPMDMGTIKKRLENRYYRNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKMF 127
BLAST of Bromodomain containing 2 vs. Ensembl Cavefish
Match: BRD3 (bromodomain-containing protein 3-like [Source:NCBI gene;Acc:103046549]) HSP 1 Score: 115.931 bits (289), Expect = 4.484e-26 Identity = 51/74 (68.92%), Postives = 65/74 (87.84%), Query Frame = 2
Query: 1685 EDCKPMSYDDKRKLSMDINQLPGDKLGRIVQIIQEREPTLRDSNPDEIEIDFEVLHPVTLRELQKFVQSVLSRQ 1906
E+ PMSYD+KR+LS+DIN+LPG+KLGR+V IIQ REP+LRDSNPDEIEIDFE L P TLREL+++V+S L ++
Sbjct: 576 EEALPMSYDEKRQLSLDINRLPGEKLGRVVHIIQSREPSLRDSNPDEIEIDFETLKPSTLRELERYVKSCLQKK 649 HSP 2 Score: 113.235 bits (282), Expect = 3.195e-25 Identity = 46/109 (42.20%), Postives = 71/109 (65.14%), Query Frame = 2
Query: 203 TNRLQFIKKKILPQLMRHKYSFPFLHPVDHAALNIPDYPKIIHYPMDFTTVKNRLIKKFYYNADECITDIRLVFQNCYIFNPPEIDLISMTLTLENIFNSKLDKLPSQE 529
TN+LQ+++ ++ L RH++++PF PVD L++PDY K+I PMD T+K RL +Y+ A EC+ D +F NCYI+N P D++ M LE IF K+ ++P +E
Sbjct: 32 TNQLQYMQNVVVKTLWRHQFAWPFYTPVDAIKLSLPDYHKVIKNPMDMGTIKKRLENNYYWTAGECMQDFNTMFTNCYIYNKPTDDIVLMAQALEKIFLQKVAQMPQEE 140 HSP 3 Score: 100.138 bits (248), Expect = 3.833e-21 Identity = 48/119 (40.34%), Postives = 71/119 (59.66%), Query Frame = 2
Query: 797 NESLDEIPIKPKLSEELKMCSNILRDISSNRYRHLNDMFMEPVAVRFPNLSDYSSIIKKPMDLSTIRKNLDDGSYKTKNDFSEDVKLIFDNCYDYNGKDSDISKLAKDLQNIFDELFSK 1153
NE L + K KLS+ LK C IL+++ S ++ F +PV L DY IIK+PMDLST++K +D Y F+ DV+L+F NCY YN D ++ +A+ LQ++F+ F+K
Sbjct: 280 NELLQQGNKKGKLSDHLKHCDTILKEMLSKKHAAYAWPFYKPVDAEALELHDYHEIIKQPMDLSTVKKKMDGREYPDAQSFAADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRFAK 398 HSP 4 Score: 88.9669 bits (219), Expect = 1.351e-17 Identity = 38/101 (37.62%), Postives = 64/101 (63.37%), Query Frame = 2
Query: 233 ILPQLMRHK---YSFPFLHPVDHAALNIPDYPKIIHYPMDFTTVKNRLIKKFYYNADECITDIRLVFQNCYIFNPPEIDLISMTLTLENIFNSKLDKLPSQ 526
IL +++ K Y++PF PVD AL + DY +II PMD +TVK ++ + Y +A D+RL+F NCY +NPP+ ++++M L+++F + K+P +
Sbjct: 302 ILKEMLSKKHAAYAWPFYKPVDAEALELHDYHEIIKQPMDLSTVKKKMDGREYPDAQSFAADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRFAKMPDE 402 HSP 5 Score: 63.929 bits (154), Expect = 7.084e-10 Identity = 33/84 (39.29%), Postives = 48/84 (57.14%), Query Frame = 2
Query: 890 YRH-LNDMFMEPV-AVRFPNLSDYSSIIKKPMDLSTIRKNLDDGSYKTKNDFSEDVKLIFDNCYDYNGKDSDISKLAKDLQNIF 1135
+RH F PV A++ +L DY +IK PMD+ TI+K L++ Y T + +D +F NCY YN DI +A+ L+ IF
Sbjct: 47 WRHQFAWPFYTPVDAIKL-SLPDYHKVIKNPMDMGTIKKRLENNYYWTAGECMQDFNTMFTNCYIYNKPTDDIVLMAQALEKIF 129
BLAST of Bromodomain containing 2 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000008098.1 (pep scaffold:Pmarinus_7.0:GL481104:2991:16154:-1 gene:ENSPMAG00000007319.1 transcript:ENSPMAT00000008098.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 125.561 bits (314), Expect = 6.518e-30 Identity = 52/109 (47.71%), Postives = 75/109 (68.81%), Query Frame = 2
Query: 203 TNRLQFIKKKILPQLMRHKYSFPFLHPVDHAALNIPDYPKIIHYPMDFTTVKNRLIKKFYYNADECITDIRLVFQNCYIFNPPEIDLISMTLTLENIFNSKLDKLPSQE 529
TN+LQF+++ +L L RH +++PFL PVD AALN+PDY KII PMD T+K RL +Y++A ECI+D + +F NCY++N P D+ M LE F K+ ++P +E
Sbjct: 36 TNQLQFMQRSVLKVLWRHHFAWPFLQPVDAAALNLPDYHKIIKQPMDMGTIKQRLESSYYWSASECISDFKTMFNNCYVYNKPGDDIAIMAQALEKAFLQKITEMPVEE 144 HSP 2 Score: 105.916 bits (263), Expect = 1.089e-23 Identity = 46/70 (65.71%), Postives = 60/70 (85.71%), Query Frame = 2
Query: 1697 PMSYDDKRKLSMDINQLPGDKLGRIVQIIQEREPTLRDSNPDEIEIDFEVLHPVTLRELQKFVQSVLSRQ 1906
PMSY++KR+LS+DIN+LPGD+LGR+V IIQ R+P+LR SNPDEIEIDFE L TLRELQ++V + L ++
Sbjct: 605 PMSYEEKRQLSLDINKLPGDRLGRVVHIIQARQPSLRGSNPDEIEIDFETLKVSTLRELQRYVGACLRKR 674 HSP 3 Score: 95.9005 bits (237), Expect = 1.706e-20 Identity = 44/127 (34.65%), Postives = 73/127 (57.48%), Query Frame = 2
Query: 773 PSPSISLKNESLDEIPIKPKLSEELKMCSNILRDISSNRYRHLNDMFMEPVAVRFPNLSDYSSIIKKPMDLSTIRKNLDDGSYKTKNDFSEDVKLIFDNCYDYNGKDSDISKLAKDLQNIFDELFSK 1153
P IS+ N ++ + + S +L+ C ++L+++ S + F PV R L DY IIK PMDL TIR+ L+ Y + +F+ DV+L+F NCY YN + D+ +A+ LQ++F+ F++
Sbjct: 299 PRKEISMANVAVVAC-ARSRPSAQLRYCGSLLKELISKNHAAYAWPFYNPVDARALGLHDYHDIIKHPMDLGTIRRKLEAREYASGQEFASDVRLMFSNCYKYNPPEHDVVAMARKLQDVFEMRFAR 424 HSP 4 Score: 89.3521 bits (220), Expect = 1.737e-18 Identity = 34/86 (39.53%), Postives = 57/86 (66.28%), Query Frame = 2
Query: 260 YSFPFLHPVDHAALNIPDYPKIIHYPMDFTTVKNRLIKKFYYNADECITDIRLVFQNCYIFNPPEIDLISMTLTLENIFNSKLDKL 517
Y++PF +PVD AL + DY II +PMD T++ +L + Y + E +D+RL+F NCY +NPPE D+++M L+++F + ++
Sbjct: 340 YAWPFYNPVDARALGLHDYHDIIKHPMDLGTIRRKLEAREYASGQEFASDVRLMFSNCYKYNPPEHDVVAMARKLQDVFEMRFARM 425 HSP 5 Score: 70.4774 bits (171), Expect = 1.273e-12 Identity = 31/80 (38.75%), Postives = 47/80 (58.75%), Query Frame = 2
Query: 896 HLNDMFMEPVAVRFPNLSDYSSIIKKPMDLSTIRKNLDDGSYKTKNDFSEDVKLIFDNCYDYNGKDSDISKLAKDLQNIF 1135
H F++PV NL DY IIK+PMD+ TI++ L+ Y + ++ D K +F+NCY YN DI+ +A+ L+ F
Sbjct: 54 HFAWPFLQPVDAAALNLPDYHKIIKQPMDMGTIKQRLESSYYWSASECISDFKTMFNNCYVYNKPGDDIAIMAQALEKAF 133
BLAST of Bromodomain containing 2 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000008812.1 (pep scaffold:Pmarinus_7.0:GL478772:7873:35829:1 gene:ENSPMAG00000007951.1 transcript:ENSPMAT00000008812.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 117.857 bits (294), Expect = 2.109e-27 Identity = 51/109 (46.79%), Postives = 73/109 (66.97%), Query Frame = 2
Query: 203 TNRLQFIKKKILPQLMRHKYSFPFLHPVDHAALNIPDYPKIIHYPMDFTTVKNRLIKKFYYNADECITDIRLVFQNCYIFNPPEIDLISMTLTLENIFNSKLDKLPSQE 529
TN+LQ+++K ++ L +H++++PF HPVD A LN+PDY II PMD T+K RL FY+ A ECI D +F NCYI+N P D++ M TLE F K+ ++P +E
Sbjct: 31 TNQLQYLQKVVMKALWKHQFAWPFHHPVDAAKLNLPDYYNIIKNPMDMGTIKKRLESNFYFTAVECIQDFSTMFTNCYIYNRPNDDIVLMAQTLEKFFLQKVAEMPVEE 139 HSP 2 Score: 114.775 bits (286), Expect = 1.945e-26 Identity = 51/74 (68.92%), Postives = 65/74 (87.84%), Query Frame = 2
Query: 1685 EDCKPMSYDDKRKLSMDINQLPGDKLGRIVQIIQEREPTLRDSNPDEIEIDFEVLHPVTLRELQKFVQSVLSRQ 1906
ED +PM+YD+KR+LS+DIN+LPGDKLGR+V IIQ REP+LR+SNPDEIEIDFE L P TLREL+++V S L ++
Sbjct: 559 EDSQPMTYDEKRQLSLDINKLPGDKLGRVVHIIQAREPSLRESNPDEIEIDFETLKPSTLRELERYVVSCLRKK 632 HSP 3 Score: 65.4698 bits (158), Expect = 4.070e-11 Identity = 43/137 (31.39%), Postives = 69/137 (50.36%), Query Frame = 2
Query: 818 PIKP-KLSEELKMCSNILRDISSNRYRH-LNDMFMEPVAVRFPNLSDYSSIIKKPMDLSTIRKNLDDGSYKTKNDFSEDVKLIFDNCYDYNGKDSDISKLAKDLQNIF----DELFSKQFNLSKPQPSQVQNSKIKS 1210
P+KP +L+ +L+ + + ++H F PV NL DY +IIK PMD+ TI+K L+ Y T + +D +F NCY YN + DI +A+ L+ F E+ ++ L++P P + KS
Sbjct: 24 PVKPGRLTNQLQYLQKV---VMKALWKHQFAWPFHHPVDAAKLNLPDYYNIIKNPMDMGTIKKRLESNFYFTAVECIQDFSTMFTNCYIYNRPNDDIVLMAQTLEKFFLQKVAEMPVEEIELAQPVPRGPRGRGRKS 157 HSP 4 Score: 49.6766 bits (117), Expect = 2.892e-6 Identity = 29/108 (26.85%), Postives = 55/108 (50.93%), Query Frame = 2
Query: 830 KLSEELKMCSNILRDISSNRYRHLNDMFMEPVAVRFPNLSDYSSIIKKPMDLSTIRKNLDDGSYKTKNDFSEDVKLIFDNCYDYNGKDSDISKLAKDLQNIFDELFSK 1153
++SE+LK CS+I++++ + ++ F +PV L DY IIK PMDLSTI+ L+ + ++ ++ +A++L ++F+ F+K
Sbjct: 296 QMSEQLKHCSSIIKEMLAKKHAAYAWPFYKPVDAESLGLHDYHDIIKHPMDLSTIKTFLEGRRFLEYPLMETSLRCCLFIALTKIQCCHKLALMARNLVDVFEMRFAK 403
BLAST of Bromodomain containing 2 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000002730.1 (pep scaffold:Pmarinus_7.0:GL482934:3:7765:-1 gene:ENSPMAG00000002495.1 transcript:ENSPMAT00000002730.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 111.694 bits (278), Expect = 3.110e-26 Identity = 49/123 (39.84%), Postives = 79/123 (64.23%), Query Frame = 2
Query: 176 GKPRPANIS-----TNRLQFIKKKILPQLMRHKYSFPFLHPVDHAALNIPDYPKIIHYPMDFTTVKNRLIKKFYYNADECITDIRLVFQNCYIFNPPEIDLISMTLTLENIFNSKLDKLPSQE 529
G+P AN + TN+LQ++++ ++ L +H++++PF PVD AL++PDY KII PMD T++ RL +Y++ ECI D +F NCY++N P D++ M TLE +F K+ +P +E
Sbjct: 49 GQPETANPNKPGRLTNQLQYLQRTVMKALWKHQFAWPFNVPVDANALHLPDYHKIIKQPMDMGTIRRRLENNYYWSGGECIQDFNTMFTNCYLYNKPTDDIVLMAQTLERLFLQKVALMPQEE 171 HSP 2 Score: 94.7449 bits (234), Expect = 9.673e-21 Identity = 43/105 (40.95%), Postives = 67/105 (63.81%), Query Frame = 2
Query: 824 KPKLSEELKMCSNILRDISSNRYRHLNDMFMEPVAVRFPNLSDYSSIIKKPMDLSTIRKNLDDGSYKTKNDFSEDVKLIFDNCYDYNGKDSDISKLAKDLQNIFD 1138
K KLSE+LK C+ IL+++ + ++ F +PV L DY IIK PMDLSTI+ +D+ Y+ +F+ DV+++F NCY YN D D+ +A+ LQ++F+
Sbjct: 326 KVKLSEQLKHCNGILKELFAKKHAAYAWPFYKPVDASTLGLHDYHDIIKHPMDLSTIKNKMDNRDYRDAQEFAADVRVMFSNCYKYNPPDHDVVSMARKLQDVFE 430 HSP 3 Score: 86.2705 bits (212), Expect = 6.193e-18 Identity = 34/79 (43.04%), Postives = 55/79 (69.62%), Query Frame = 2
Query: 260 YSFPFLHPVDHAALNIPDYPKIIHYPMDFTTVKNRLIKKFYYNADECITDIRLVFQNCYIFNPPEIDLISMTLTLENIF 496
Y++PF PVD + L + DY II +PMD +T+KN++ + Y +A E D+R++F NCY +NPP+ D++SM L+++F
Sbjct: 351 YAWPFYKPVDASTLGLHDYHDIIKHPMDLSTIKNKMDNRDYRDAQEFAADVRVMFSNCYKYNPPDHDVVSMARKLQDVF 429 HSP 4 Score: 62.003 bits (149), Expect = 3.753e-10 Identity = 33/99 (33.33%), Postives = 53/99 (53.54%), Query Frame = 2
Query: 911 FMEPVAVRFPNLSDYSSIIKKPMDLSTIRKNLDDGSYKTKNDFSEDVKLIFDNCYDYNGKDSDISKLAKDLQNIFDELFS----KQFNLSKPQPSQVQN 1195
F PV +L DY IIK+PMD+ TIR+ L++ Y + + +D +F NCY YN DI +A+ L+ +F + + ++ L+ P P V+
Sbjct: 86 FNVPVDANALHLPDYHKIIKQPMDMGTIRRRLENNYYWSGGECIQDFNTMFTNCYLYNKPTDDIVLMAQTLERLFLQKVALMPQEEVVLASPGPKAVKG 184
BLAST of Bromodomain containing 2 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000002732.1 (pep scaffold:Pmarinus_7.0:GL482934:3:7597:-1 gene:ENSPMAG00000002495.1 transcript:ENSPMAT00000002732.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 109.383 bits (272), Expect = 1.255e-25 Identity = 45/109 (41.28%), Postives = 73/109 (66.97%), Query Frame = 2
Query: 203 TNRLQFIKKKILPQLMRHKYSFPFLHPVDHAALNIPDYPKIIHYPMDFTTVKNRLIKKFYYNADECITDIRLVFQNCYIFNPPEIDLISMTLTLENIFNSKLDKLPSQE 529
TN+LQ++++ ++ L +H++++PF PVD AL++PDY KII PMD T++ RL +Y++ ECI D +F NCY++N P D++ M TLE +F K+ +P +E
Sbjct: 32 TNQLQYLQRTVMKALWKHQFAWPFNVPVDANALHLPDYHKIIKQPMDMGTIRRRLENNYYWSGGECIQDFNTMFTNCYLYNKPTDDIVLMAQTLERLFLQKVALMPQEE 140 HSP 2 Score: 95.1301 bits (235), Expect = 6.132e-21 Identity = 43/105 (40.95%), Postives = 67/105 (63.81%), Query Frame = 2
Query: 824 KPKLSEELKMCSNILRDISSNRYRHLNDMFMEPVAVRFPNLSDYSSIIKKPMDLSTIRKNLDDGSYKTKNDFSEDVKLIFDNCYDYNGKDSDISKLAKDLQNIFD 1138
K KLSE+LK C+ IL+++ + ++ F +PV L DY IIK PMDLSTI+ +D+ Y+ +F+ DV+++F NCY YN D D+ +A+ LQ++F+
Sbjct: 308 KVKLSEQLKHCNGILKELFAKKHAAYAWPFYKPVDASTLGLHDYHDIIKHPMDLSTIKNKMDNRDYRDAQEFAADVRVMFSNCYKYNPPDHDVVSMARKLQDVFE 412 HSP 3 Score: 85.1149 bits (209), Expect = 1.146e-17 Identity = 34/79 (43.04%), Postives = 55/79 (69.62%), Query Frame = 2
Query: 260 YSFPFLHPVDHAALNIPDYPKIIHYPMDFTTVKNRLIKKFYYNADECITDIRLVFQNCYIFNPPEIDLISMTLTLENIF 496
Y++PF PVD + L + DY II +PMD +T+KN++ + Y +A E D+R++F NCY +NPP+ D++SM L+++F
Sbjct: 333 YAWPFYKPVDASTLGLHDYHDIIKHPMDLSTIKNKMDNRDYRDAQEFAADVRVMFSNCYKYNPPDHDVVSMARKLQDVF 411 HSP 4 Score: 62.003 bits (149), Expect = 2.816e-10 Identity = 33/99 (33.33%), Postives = 53/99 (53.54%), Query Frame = 2
Query: 911 FMEPVAVRFPNLSDYSSIIKKPMDLSTIRKNLDDGSYKTKNDFSEDVKLIFDNCYDYNGKDSDISKLAKDLQNIFDE----LFSKQFNLSKPQPSQVQN 1195
F PV +L DY IIK+PMD+ TIR+ L++ Y + + +D +F NCY YN DI +A+ L+ +F + + ++ L+ P P V+
Sbjct: 55 FNVPVDANALHLPDYHKIIKQPMDMGTIRRRLENNYYWSGGECIQDFNTMFTNCYLYNKPTDDIVLMAQTLERLFLQKVALMPQEEVVLASPGPKAVKG 153
BLAST of Bromodomain containing 2 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000004772.1 (pep scaffold:Pmarinus_7.0:GL477964:1616:15578:1 gene:ENSPMAG00000004315.1 transcript:ENSPMAT00000004772.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 71.633 bits (174), Expect = 5.685e-13 Identity = 34/99 (34.34%), Postives = 58/99 (58.59%), Query Frame = 2
Query: 863 ILRDISSNRYRHLNDMFMEPVAVRFPNLSDYSSIIKKPMDLSTIRKNLDDGSYKTKNDFSEDVKLIFDNCYDYNGKDSDISKLAKDLQNIFDELFSKQF 1159
+ R ++++Y ++F++PV Y SI+ +PMDLSTI+KN+++G+ +T +F DV L+F N YN D D+ +A ++Q E +QF
Sbjct: 784 VWRAAANHKY---ANVFLQPVTNDI--APGYHSIVHRPMDLSTIKKNIENGAIRTTAEFQRDVMLMFQNAIMYNSSDHDVFHMAVEMQRDVMEHVQQQF 877 HSP 2 Score: 50.0618 bits (118), Expect = 2.520e-6 Identity = 25/78 (32.05%), Postives = 40/78 (51.28%), Query Frame = 2
Query: 254 HKYSFPFLHPVDHAALNIPDYPKIIHYPMDFTTVKNRLIKKFYYNADECITDIRLVFQNCYIFNPPEIDLISMTLTLE 487
HKY+ FL PV + P Y I+H PMD +T+K + E D+ L+FQN ++N + D+ M + ++
Sbjct: 791 HKYANVFLQPVTNDIA--PGYHSIVHRPMDLSTIKKNIENGAIRTTAEFQRDVMLMFQNAIMYNSSDHDVFHMAVEMQ 866
BLAST of Bromodomain containing 2 vs. Ensembl Yeast
Match: BDF2 (Protein involved in transcription initiation; acts at TATA-containing promoters; associates with the basal transcription factor TFIID; contains two bromodomains; corresponds to the C-terminal region of mammalian TAF1; redundant with Bdf1p; protein abundance increases in response to DNA replication stress; BDF2 has a paralog, BDF1, that arose from the whole genome duplication [Source:SGD;Acc:S000002228]) HSP 1 Score: 108.612 bits (270), Expect = 7.692e-25 Identity = 81/301 (26.91%), Postives = 139/301 (46.18%), Query Frame = 2
Query: 251 RHKYSFPFLHPVDHAALNIPDYPKIIHYPMDFTTVKNRLIKKFYYNADECITDIRLVFQNCYIFNPPEIDLISMTLTLENIFNSKLDKLPSQEXXXXXXXXXXXXXXXXXXXXXXXEPVCDIKKSLRPTTKRLKXXXXXXXXXXXXXXXCSISPDAKSKAKKRKVESCYDLSPTPSPSISLKNESLDEI-----PIKPKLSEELKMCSNILRDISSNRYRHLNDMFMEPVAVRFPNLSDYSSIIKKPMDLSTIRKNLDDGSYKTKNDFSEDVKLIFDNCYDYNGKDSDISKLAKDLQNIFD 1138
R K + PFL PVD ALNIP Y + PMD + ++ +L Y++ ++ +D + + NC FN PE + SM ++ F KL +P + P +KK T R + + ++ + S + D ++ R+ S T P K++ L +I P L ++ + C IL+ + S + +N F++PV NL +Y ++K PMDL TI NL + YKT + F +D+ L+F NC+ +N + +++ + K L+ +F+
Sbjct: 151 RLKDARPFLKPVDPIALNIPHYFNYVQTPMDLSLIETKLQGNVYHSVEQVTSDFKTMVDNCLNFNGPESSISSMAKRIQKYFEKKLSAMPPRVL-----------------------PASALKK-----TSRNRKKNEDMDSPLVIRRSVSTTNDNIGESGNREGVSGGRPKRTIHPP---KSKDLFDIYENSKPKSKTLQKKFRTCLKILKVLMSKKNSDINFPFLQPVDPIALNLPNYFDVVKNPMDLGTISNNLMNWKYKTIDQFVDDLNLVFYNCFQFNPEGNEVHSMGKKLKELFN 420 HSP 2 Score: 78.1814 bits (191), Expect = 2.838e-15 Identity = 41/93 (44.09%), Postives = 55/93 (59.14%), Query Frame = 2
Query: 230 KILPQLMRHKYS---FPFLHPVDHAALNIPDYPKIIHYPMDFTTVKNRLIKKFYYNADECITDIRLVFQNCYIFNPPEIDLISMTLTLENIFN 499
KIL LM K S FPFL PVD ALN+P+Y ++ PMD T+ N L+ Y D+ + D+ LVF NC+ FNP ++ SM L+ +FN
Sbjct: 328 KILKVLMSKKNSDINFPFLQPVDPIALNLPNYFDVVKNPMDLGTISNNLMNWKYKTIDQFVDDLNLVFYNCFQFNPEGNEVHSMGKKLKELFN 420 HSP 3 Score: 55.4546 bits (132), Expect = 3.503e-8 Identity = 27/79 (34.18%), Postives = 45/79 (56.96%), Query Frame = 2
Query: 914 MEPVAVRFPNLSDYSSIIKKPMDLSTIRKNLDDGSYKTKNDFSEDVKLIFDNCYDYNGKDSDISKLAKDLQNIFDELFS 1150
++P+A+ P+ +Y ++ PMDLS I L Y + + D K + DNC ++NG +S IS +AK +Q F++ S
Sbjct: 162 VDPIALNIPHYFNY---VQTPMDLSLIETKLQGNVYHSVEQVTSDFKTMVDNCLNFNGPESSISSMAKRIQKYFEKKLS 237
BLAST of Bromodomain containing 2 vs. Ensembl Yeast
Match: BDF1 (Protein involved in transcription initiation; functions at TATA-containing promoters; associates with the basal transcription factor TFIID; contains two bromodomains; corresponds to the C-terminal region of mammalian TAF1; redundant with Bdf2p; BDF1 has a paralog, BDF2, that arose from the whole genome duplication [Source:SGD;Acc:S000004391]) HSP 1 Score: 83.5741 bits (205), Expect = 7.352e-17 Identity = 39/116 (33.62%), Postives = 68/116 (58.62%), Query Frame = 2
Query: 818 PIKPKLSEELKMCSNILRDISSNRYRHLNDMFMEPVAVRFPNLSDYSSIIKKPMDLSTIRKNLDDGSYKTKNDFSEDVKLIFDNCYDYNGKDSDISKLAKDLQNIFDELFSKQFNL 1165
P +L + +K C ++L+++ + ++ N F+EPV NL Y +K+PMDL TI K L+D Y+T DF DV+L+F NCY +N + ++ + L+ +F+ ++ + NL
Sbjct: 309 PKSKRLQQAMKFCQSVLKELMAKKHASYNYPFLEPVDPVSMNLPTYFDYVKEPMDLGTIAKKLNDWQYQTMEDFERDVRLVFKNCYTFNPDGTIVNMMGHRLEEVFNSKWADRPNL 424 HSP 2 Score: 79.337 bits (194), Expect = 1.224e-15 Identity = 39/100 (39.00%), Postives = 56/100 (56.00%), Query Frame = 2
Query: 233 ILPQLMRHK---YSFPFLHPVDHAALNIPDYPKIIHYPMDFTTVKNRLIKKFYYNADECITDIRLVFQNCYIFNPPEIDLISMTLTLENIFNSKLDKLPS 523
+L +LM K Y++PFL PVD ++N+P Y + PMD T+ +L Y ++ D+RLVF+NCY FNP + M LE +FNSK P+
Sbjct: 324 VLKELMAKKHASYNYPFLEPVDPVSMNLPTYFDYVKEPMDLGTIAKKLNDWQYQTMEDFERDVRLVFKNCYTFNPDGTIVNMMGHRLEEVFNSKWADRPN 423 HSP 3 Score: 56.225 bits (134), Expect = 1.896e-8 Identity = 27/76 (35.53%), Postives = 49/76 (64.47%), Query Frame = 2
Query: 911 FMEPVAVRFPNLSDYSSIIKKPMDLSTIRKNLDDGSYKTKNDFSEDVKLIFDNCYDYNGKDSDISKLAKDLQNIFD 1138
F++PV ++ Y + IK+PMDLSTI + L+ G+Y+ +ED L+ +N +NG ++ IS++A+++Q F+
Sbjct: 173 FLQPVDPVKLDIPFYFNYIKRPMDLSTIERKLNVGAYEVPEQITEDFNLMVNNSIKFNGPNAGISQMARNIQASFE 248 HSP 4 Score: 52.373 bits (124), Expect = 2.656e-7 Identity = 28/93 (30.11%), Postives = 45/93 (48.39%), Query Frame = 2
Query: 251 RHKYSFPFLHPVDHAALNIPDYPKIIHYPMDFTTVKNRLIKKFYYNADECITDIRLVFQNCYIFNPPEIDLISMTLTLENIFNSKLDKLPSQE 529
R K + PFL PVD L+IP Y I PMD +T++ +L Y ++ D L+ N FN P + M ++ F + +P+++
Sbjct: 166 RLKDARPFLQPVDPVKLDIPFYFNYIKRPMDLSTIERKLNVGAYEVPEQITEDFNLMVNNSIKFNGPNAGISQMARNIQASFEKHMLNMPAKD 258
BLAST of Bromodomain containing 2 vs. Ensembl Yeast
Match: GCN5 (Catalytic subunit of ADA and SAGA histone acetyltransferase complexes; modifies N-terminal lysines on histones H2B and H3; acetylates Rsc4p, a subunit of the RSC chromatin-remodeling complex, altering replication stress tolerance; relocalizes to the cytosol in response to hypoxia; mutant displays reduced transcription elongation in the G-less-based run-on (GLRO) assay; greater involvement in repression of RNAPII-dependent transcription than in activation [Source:SGD;Acc:S000003484]) HSP 1 Score: 64.6994 bits (156), Expect = 3.087e-11 Identity = 34/96 (35.42%), Postives = 51/96 (53.12%), Query Frame = 2
Query: 233 ILPQLMRHKYSFPFLHPVDHAALNIPDYPKIIHYPMDFTTVKNRLIKKFYYNADECITDIRLVFQNCYIFNPPEIDLISMTLTLENIFNSKLDKLP 520
IL +L H ++PFL PV+ +PDY I PMD +T++ +L Y ++ I D RLVF NC ++N LE FN+K+ ++P
Sbjct: 339 ILTELQNHAAAWPFLQPVNKE--EVPDYYDFIKEPMDLSTMEIKLESNKYQKMEDFIYDARLVFNNCRMYNGENTSYYKYANRLEKFFNNKVKEIP 432 HSP 2 Score: 59.6918 bits (143), Expect = 1.303e-9 Identity = 36/112 (32.14%), Postives = 57/112 (50.89%), Query Frame = 2
Query: 806 LDEIPIKPKLSEELKMCSNILRDISSNRYRHLNDM-FMEPVAVRFPNLSDYSSIIKKPMDLSTIRKNLDDGSYKTKNDFSEDVKLIFDNCYDYNGKDSDISKLAKDLQNIFD 1138
+D + +PK NIL ++ + H F++PV + DY IK+PMDLST+ L+ Y+ DF D +L+F+NC YNG+++ K A L+ F+
Sbjct: 320 MDALAQRPKRGPHDAAIQNILTELQN----HAAAWPFLQPVNKE--EVPDYYDFIKEPMDLSTMEIKLESNKYQKMEDFIYDARLVFNNCRMYNGENTSYYKYANRLEKFFN 425
BLAST of Bromodomain containing 2 vs. Ensembl Yeast
Match: RSC4 (Component of the RSC chromatin remodeling complex; found in close proximity to nucleosomal DNA; displaced from the surface of nucleosomal DNA after chromatin remodeling; acetylated (K25) by Gcn5p, altering replication stress tolerance; contains tandem bromodomains that recognize histone H3 acetylated on K14 (H3K14ac) by Gcn5p [Source:SGD;Acc:S000001716]) HSP 1 Score: 53.1434 bits (126), Expect = 1.511e-7 Identity = 34/86 (39.53%), Postives = 44/86 (51.16%), Query Frame = 2
Query: 257 KYSFPFLHPVDHAALNIPDYPKIIHYPMDFTTVKNRLIKKFYYNADECITDIRLVFQNCYIFNPPEIDLISMTLTLENIFNSKLDK 514
K S PF+ VD L P+Y +I+H PM + VK L Y + I D+ LVFQN +IFN P + TL N FN + K
Sbjct: 208 KLSEPFMELVDKDEL--PEYYEIVHSPMALSIVKQNLEIGQYSKIYDFIIDMLLVFQNAHIFNDPSALIYKDATTLTNYFNYLIQK 291 HSP 2 Score: 50.0618 bits (118), Expect = 1.327e-6 Identity = 32/87 (36.78%), Postives = 47/87 (54.02%), Query Frame = 2
Query: 899 LNDMFMEPVAVRFPNLSDYSSIIKKPMDLSTIRKNLDDGSYKTKNDFSEDVKLIFDNCYDYNGKDSDISKLAKDLQNIFDELFSKQF 1159
L++ FME V L +Y I+ PM LS +++NL+ G Y DF D+ L+F N + +N + I K A L N F+ L K+F
Sbjct: 209 LSEPFME--LVDKDELPEYYEIVHSPMALSIVKQNLEIGQYSKIYDFIIDMLLVFQNAHIFNDPSALIYKDATTLTNYFNYLIQKEF 293
BLAST of Bromodomain containing 2 vs. Ensembl Nematostella
Match: EDO31846 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SWS3]) HSP 1 Score: 109.768 bits (273), Expect = 1.059e-28 Identity = 51/74 (68.92%), Postives = 61/74 (82.43%), Query Frame = 2
Query: 1685 EDCKPMSYDDKRKLSMDINQLPGDKLGRIVQIIQEREPTLRDSNPDEIEIDFEVLHPVTLRELQKFVQSVLSRQ 1906
E K M+YD+KR+LS+DIN+LPG KLGR+V IIQ RE LRDSNPDEIEIDFE L P TLREL+K+VQS L ++
Sbjct: 6 ETAKAMTYDEKRQLSLDINRLPGPKLGRVVHIIQSREKQLRDSNPDEIEIDFETLAPSTLRELEKYVQSCLRKK 79
BLAST of Bromodomain containing 2 vs. Ensembl Nematostella
Match: EDO31845 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SWS2]) HSP 1 Score: 108.997 bits (271), Expect = 6.207e-25 Identity = 49/117 (41.88%), Postives = 72/117 (61.54%), Query Frame = 2
Query: 179 KPRPANISTNRLQFIKKKILPQLMRHKYSFPFLHPVDHAALNIPDYPKIIHYPMDFTTVKNRLIKKFYYNADECITDIRLVFQNCYIFNPPEIDLISMTLTLENIFNSKLDKLPSQE 529
+P P +TN+LQF+ K +L L RH +++PF PVD LN+PDY II PMD T+K +L Y A ECI D RL+ NCY +N P D++ M +++ +F+ K+ +P +E
Sbjct: 8 QPAPKTRTTNQLQFLLKTVLKGLWRHHHAWPFREPVDAVKLNLPDYHTIIKKPMDLGTIKKKLENNEYPCAQECIEDFRLMINNCYTYNKPGDDIVLMCQSMDKLFHQKIAMMPPEE 124 HSP 2 Score: 103.219 bits (256), Expect = 4.182e-23 Identity = 53/177 (29.94%), Postives = 102/177 (57.63%), Query Frame = 2
Query: 833 LSEELKMCSNILRDISSNRYRHLNDMFMEPVAVRFPNLSDYSSIIKKPMDLSTIRKNLDDGSYKTKNDFSEDVKLIFDNCYDYNGKDSDISKLAKDLQNIFDELFSK------------QFNLSKPQPSQVQNSKIKSESVNEDTLQLLQKIHKEQKSLVETHNKVAEKIIKQNLLI 1327
L+E+LK CS IL+D+ S ++ F +PV L DY IIK+PMD++ I+ L++ +Y + ++F+ D++L+F NCY YN D D+ K+A+ LQ++F+ F+K + +P Q ++S ++ N+ + +K+ + Q+ L+ H +++ K+ +++L+
Sbjct: 283 LTEQLKYCSTILKDMFSKKHYAYAWPFYKPVDAEALGLHDYHDIIKQPMDMTEIKNKLENRAYDSPSEFAADIRLMFSNCYRYNPPDHDVVKMARQLQDVFEMKFAKMPEETIIAPPSPPPAQPEVEPEQQESSDEETSVSNDSEAERAEKLSQLQQQLISVHEQLS-KLTGESVLV 458 HSP 3 Score: 90.5077 bits (223), Expect = 6.884e-19 Identity = 39/92 (42.39%), Postives = 57/92 (61.96%), Query Frame = 2
Query: 251 RHKYSFPFLHPVDHAALNIPDYPKIIHYPMDFTTVKNRLIKKFYYNADECITDIRLVFQNCYIFNPPEIDLISMTLTLENIFNSKLDKLPSQ 526
+ Y++PF PVD AL + DY II PMD T +KN+L + Y + E DIRL+F NCY +NPP+ D++ M L+++F K K+P +
Sbjct: 302 HYAYAWPFYKPVDAEALGLHDYHDIIKQPMDMTEIKNKLENRAYDSPSEFAADIRLMFSNCYRYNPPDHDVVKMARQLQDVFEMKFAKMPEE 393 HSP 4 Score: 73.9442 bits (180), Expect = 1.273e-13 Identity = 40/111 (36.04%), Postives = 64/111 (57.66%), Query Frame = 2
Query: 863 ILRDISSNRYRHLNDM-FMEPV-AVRFPNLSDYSSIIKKPMDLSTIRKNLDDGSYKTKNDFSEDVKLIFDNCYDYNGKDSDISKLAKDLQNIFDELFSKQFNLSKPQPSQV 1189
+L+ + +RH + F EPV AV+ NL DY +IIKKPMDL TI+K L++ Y + ED +L+ +NCY YN DI + + + D+LF ++ + P+ ++
Sbjct: 22 LLKTVLKGLWRHHHAWPFREPVDAVKL-NLPDYHTIIKKPMDLGTIKKKLENNEYPCAQECIEDFRLMINNCYTYNKPGDDIVLMCQSM----DKLFHQKIAMMPPEEKEI 127
BLAST of Bromodomain containing 2 vs. Ensembl Nematostella
Match: EDO44902 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RUH0]) HSP 1 Score: 68.9366 bits (167), Expect = 1.281e-13 Identity = 36/109 (33.03%), Postives = 59/109 (54.13%), Query Frame = 2
Query: 203 TNRLQFIKKKILPQLMRHKYSFPFLHPVDHAALNIPDYPKIIHYPMDFTTVKNRLIKKFYYNADECITDIRLVFQNCYIFNPPEIDLISMTLTLENIFNSKLDKLPSQE 529
TNR K++L L HK ++PFL PV + L++P Y +I PMD +TV++++ K Y ++ ++D+ +F NC FN + LE +F KL S++
Sbjct: 49 TNRDHDSLKRMLRSLQSHKMAWPFLEPV--SGLDVPGYYDVIKEPMDLSTVEDKITSKKYATLEQFVSDVTRIFDNCRFFNGKDTPYYRCAEVLEAVFVQKLRAWKSKK 155 HSP 2 Score: 59.3066 bits (142), Expect = 2.846e-10 Identity = 33/91 (36.26%), Postives = 52/91 (57.14%), Query Frame = 2
Query: 863 ILRDISSNRYRHLNDMFMEPVAVRFPNLSDYSSIIKKPMDLSTIRKNLDDGSYKTKNDFSEDVKLIFDNCYDYNGKDSDISKLAKDLQNIF 1135
+LR + S++ + F+EPV+ ++ Y +IK+PMDLST+ + Y T F DV IFDNC +NGKD+ + A+ L+ +F
Sbjct: 59 MLRSLQSHK---MAWPFLEPVSGL--DVPGYYDVIKEPMDLSTVEDKITSKKYATLEQFVSDVTRIFDNCRFFNGKDTPYYRCAEVLEAVF 144
BLAST of Bromodomain containing 2 vs. Ensembl Nematostella
Match: EDO40753 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S640]) HSP 1 Score: 68.9366 bits (167), Expect = 1.005e-11 Identity = 31/76 (40.79%), Postives = 45/76 (59.21%), Query Frame = 2
Query: 911 FMEPVAVRFPNLSDYSSIIKKPMDLSTIRKNLDDGSYKTKNDFSEDVKLIFDNCYDYNGKDSDISKLAKDLQNIFD 1138
F PV + DY I++ PMDLSTI++ LD+G YK ++ +DV L+FDN + YN K S + K L +F+
Sbjct: 691 FRSPVDPKLLGCLDYFEIVRNPMDLSTIKRKLDNGQYKNPWEYCDDVWLMFDNAWLYNRKTSRVYKYCTKLSEVFE 766 HSP 2 Score: 54.6842 bits (130), Expect = 2.267e-7 Identity = 28/83 (33.73%), Postives = 42/83 (50.60%), Query Frame = 2
Query: 263 SFPFLHPVDHAALNIPDYPKIIHYPMDFTTVKNRLIKKFYYNADECITDIRLVFQNCYIFNPPEIDLISMTLTLENIFNSKLD 511
S PF PVD L DY +I+ PMD +T+K +L Y N E D+ L+F N +++N + L +F S++D
Sbjct: 688 SLPFRSPVDPKLLGCLDYFEIVRNPMDLSTIKRKLDNGQYKNPWEYCDDVWLMFDNAWLYNRKTSRVYKYCTKLSEVFESEID 770
BLAST of Bromodomain containing 2 vs. Ensembl Nematostella
Match: EDO43844 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RXH0]) HSP 1 Score: 67.781 bits (164), Expect = 1.748e-11 Identity = 37/99 (37.37%), Postives = 53/99 (53.54%), Query Frame = 2
Query: 212 LQFIKKKILPQLMRHKYSFPFLHPVDHAALNIPDYPKIIHYPMDFTTVKNRLIKKFYYNADECITDIRLVFQNCYIFNPPEIDLISMTLTLENIFNSKL 508
LQ K IL Q+ H ++PF PV+ A PDY + I YPMD T+ RL +Y + + D+R +FQNC +N P+ + T+E F SK+
Sbjct: 654 LQTQLKNILTQVKNHASAWPFQKPVERA--EAPDYYEHIKYPMDLKTMTERLKSGYYSSKKLFVADMRRIFQNCRTYNSPDTEYYKCANTVERFFLSKI 750 HSP 2 Score: 53.5286 bits (127), Expect = 4.004e-7 Identity = 25/62 (40.32%), Postives = 34/62 (54.84%), Query Frame = 2
Query: 950 DYSSIIKKPMDLSTIRKNLDDGSYKTKNDFSEDVKLIFDNCYDYNGKDSDISKLAKDLQNIF 1135
DY IK PMDL T+ + L G Y +K F D++ IF NC YN D++ K A ++ F
Sbjct: 685 DYYEHIKYPMDLKTMTERLKSGYYSSKKLFVADMRRIFQNCRTYNSPDTEYYKCANTVERFF 746
BLAST of Bromodomain containing 2 vs. Ensembl Medaka
Match: ENSORLT00000017454.2 (bromodomain-containing protein 3 [Source:NCBI gene;Acc:101155101]) HSP 1 Score: 125.561 bits (314), Expect = 7.132e-29 Identity = 53/115 (46.09%), Postives = 78/115 (67.83%), Query Frame = 2
Query: 185 RPANISTNRLQFIKKKILPQLMRHKYSFPFLHPVDHAALNIPDYPKIIHYPMDFTTVKNRLIKKFYYNADECITDIRLVFQNCYIFNPPEIDLISMTLTLENIFNSKLDKLPSQE 529
RP + TN+L ++++ ++ L RH+YS+PF PVD AL IPDY K+I +PMD TV RL ++Y+ A+ECI DI +F NCY++N P D++ M TLE IF K+ ++P +E
Sbjct: 25 RPGRV-TNQLLYLERVVIKALWRHQYSWPFRQPVDAVALCIPDYYKLIKHPMDLGTVMQRLKNRYYWEANECIKDISTMFNNCYVYNRPGDDIVFMAQTLEKIFLQKVSQMPKEE 138 HSP 2 Score: 92.4337 bits (228), Expect = 1.198e-18 Identity = 50/139 (35.97%), Postives = 75/139 (53.96%), Query Frame = 2
Query: 776 SPSISLKNESLDEIPIKP-------------KLSEELKMCSNILRDISSNRYRHLNDMFMEPVAVRFPNLSDYSSIIKKPMDLSTIRKNLDDGSYKTKNDFSEDVKLIFDNCYDYNGKDSDISKLAKDLQNIFDELFSK 1153
S SI L + + P+KP +L+E+L+ C+NIL+++ S R+ F PV L DY IIK+PMDLSTI+K +D Y +F+ DV+L+F NCY YN + +A+ LQ +F+ + K
Sbjct: 223 SASIPLISRTGSGRPVKPPKKNLDMFEDKRVRLTEKLRDCNNILKEMLSKRHCAYAWPFYTPVDAIALGLQDYHDIIKQPMDLSTIKKKMDHQEYTNATEFAADVRLMFSNCYRYNPPSHGVVYMARKLQEVFEARYMK 361 HSP 3 Score: 87.0409 bits (214), Expect = 5.786e-17 Identity = 42/102 (41.18%), Postives = 63/102 (61.76%), Query Frame = 2
Query: 233 ILPQLM--RH-KYSFPFLHPVDHAALNIPDYPKIIHYPMDFTTVKNRLIKKFYYNADECITDIRLVFQNCYIFNPPEIDLISMTLTLENIFNSKLDKLPSQE 529
IL +++ RH Y++PF PVD AL + DY II PMD +T+K ++ + Y NA E D+RL+F NCY +NPP ++ M L+ +F ++ K+ SQE
Sbjct: 265 ILKEMLSKRHCAYAWPFYTPVDAIALGLQDYHDIIKQPMDLSTIKKKMDHQEYTNATEFAADVRLMFSNCYRYNPPSHGVVYMARKLQEVFEARYMKM-SQE 365 HSP 4 Score: 73.559 bits (179), Expect = 8.625e-13 Identity = 33/71 (46.48%), Postives = 52/71 (73.24%), Query Frame = 2
Query: 1694 KPMSYDDKRKLSMDINQLPGDKLGRIVQIIQEREPTLRDSNPDEIEIDFEVLHPVTLRELQKFVQSVLSRQ 1906
KP++Y +K++L DIN LPGDKLG ++ II+ RE L++SN +++ IDF+++ P TL LQ+FV L ++
Sbjct: 497 KPVTYQEKKQLKSDINMLPGDKLGELLNIIKSRESYLQESNLEDVVIDFDMVKPSTLTVLQRFVAECLKKR 567 HSP 5 Score: 60.077 bits (144), Expect = 1.074e-8 Identity = 30/83 (36.14%), Postives = 45/83 (54.22%), Query Frame = 2
Query: 890 YRHLNDM-FMEPVAVRFPNLSDYSSIIKKPMDLSTIRKNLDDGSYKTKNDFSEDVKLIFDNCYDYNGKDSDISKLAKDLQNIF 1135
+RH F +PV + DY +IK PMDL T+ + L + Y N+ +D+ +F+NCY YN DI +A+ L+ IF
Sbjct: 45 WRHQYSWPFRQPVDAVALCIPDYYKLIKHPMDLGTVMQRLKNRYYWEANECIKDISTMFNNCYVYNRPGDDIVFMAQTLEKIF 127
BLAST of Bromodomain containing 2 vs. Ensembl Medaka
Match: brd4 (bromodomain-containing protein 4 [Source:NCBI gene;Acc:101158947]) HSP 1 Score: 117.857 bits (294), Expect = 2.411e-26 Identity = 50/109 (45.87%), Postives = 71/109 (65.14%), Query Frame = 2
Query: 203 TNRLQFIKKKILPQLMRHKYSFPFLHPVDHAALNIPDYPKIIHYPMDFTTVKNRLIKKFYYNADECITDIRLVFQNCYIFNPPEIDLISMTLTLENIFNSKLDKLPSQE 529
TN+LQ++ K ++ L +H +S+PF PVD LN+PDY IIH PMD T+K RL +Y+NA ECI D +F NCYI+N P D++ M LE +F K+ ++P +E
Sbjct: 125 TNQLQYLLKVVVKALWKHHFSWPFQAPVDAIKLNLPDYYTIIHTPMDLGTIKKRLENSYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKVFLQKVSEMPQEE 233 HSP 2 Score: 114.775 bits (286), Expect = 2.158e-25 Identity = 49/71 (69.01%), Postives = 63/71 (88.73%), Query Frame = 2
Query: 1685 EDCKPMSYDDKRKLSMDINQLPGDKLGRIVQIIQEREPTLRDSNPDEIEIDFEVLHPVTLRELQKFVQSVL 1897
E CKPM+Y++KR+LS+DIN+LPGDKLGR+V IIQ REP+L++SNPDEIEIDFE L P TLREL+++V + L
Sbjct: 719 EKCKPMTYEEKRQLSLDINKLPGDKLGRVVHIIQSREPSLKNSNPDEIEIDFETLKPSTLRELERYVSTCL 789 HSP 3 Score: 95.5153 bits (236), Expect = 1.577e-19 Identity = 41/109 (37.61%), Postives = 68/109 (62.39%), Query Frame = 2
Query: 827 PKLSEELKMCSNILRDISSNRYRHLNDMFMEPVAVRFPNLSDYSSIIKKPMDLSTIRKNLDDGSYKTKNDFSEDVKLIFDNCYDYNGKDSDISKLAKDLQNIFDELFSK 1153
P+ ++L C+ ++R++ S ++ F +PV V L DY IIK PMDLSTI+ L++ Y+ +F+ DV+L+F NCY YN D ++ +A+ LQ++F+ F+K
Sbjct: 437 PRPQDQLGYCAALVREMLSKKHAAYAWPFYKPVDVDALGLHDYHDIIKHPMDLSTIKAKLENRQYRDPQEFAADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRFAK 545 HSP 4 Score: 87.8113 bits (216), Expect = 4.120e-17 Identity = 35/87 (40.23%), Postives = 57/87 (65.52%), Query Frame = 2
Query: 260 YSFPFLHPVDHAALNIPDYPKIIHYPMDFTTVKNRLIKKFYYNADECITDIRLVFQNCYIFNPPEIDLISMTLTLENIFNSKLDKLP 520
Y++PF PVD AL + DY II +PMD +T+K +L + Y + E D+RL+F NCY +NPP+ ++++M L+++F + K+P
Sbjct: 461 YAWPFYKPVDVDALGLHDYHDIIKHPMDLSTIKAKLENRQYRDPQEFAADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRFAKMP 547 HSP 5 Score: 65.0846 bits (157), Expect = 3.276e-10 Identity = 32/82 (39.02%), Postives = 46/82 (56.10%), Query Frame = 2
Query: 893 RHLNDMFMEPV-AVRFPNLSDYSSIIKKPMDLSTIRKNLDDGSYKTKNDFSEDVKLIFDNCYDYNGKDSDISKLAKDLQNIF 1135
H + F PV A++ NL DY +II PMDL TI+K L++ Y + +D +F NCY YN DI +A+ L+ +F
Sbjct: 142 HHFSWPFQAPVDAIKL-NLPDYYTIIHTPMDLGTIKKRLENSYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKVF 222
BLAST of Bromodomain containing 2 vs. Ensembl Medaka
Match: ENSORLT00000046532.1 (bromodomain-containing protein 3 [Source:NCBI gene;Acc:101159110]) HSP 1 Score: 116.316 bits (290), Expect = 2.651e-26 Identity = 61/132 (46.21%), Postives = 84/132 (63.64%), Query Frame = 2
Query: 1511 SKSARQKKPTQESSSNSVPAESNRTETNVASSMPATLRMPCNESYQNTELPSKTNRVTEDCKPMSYDDKRKLSMDINQLPGDKLGRIVQIIQEREPTLRDSNPDEIEIDFEVLHPVTLRELQKFVQSVLSRQ 1906
+K +KKP + ++ PA + A+S R P + + + E PMSYD+KR+LS+DIN+LPG+KLGR+V IIQ REP+LRDSNPDEIEIDFE L P TLREL+++V+S L ++
Sbjct: 497 AKIEEEKKP-KAAAQQPKPANQKKAPARKANSTVTAPRQPKKGGKTSGGGSANGDDGEESSLPMSYDEKRQLSLDINRLPGEKLGRVVHIIQSREPSLRDSNPDEIEIDFETLKPSTLRELERYVKSCLQKK 627 HSP 2 Score: 103.219 bits (256), Expect = 3.430e-22 Identity = 43/109 (39.45%), Postives = 69/109 (63.30%), Query Frame = 2
Query: 203 TNRLQFIKKKILPQLMRHKYSFPFLHPVDHAALNIPDYPKIIHYPMDFTTVKNRLIKKFYYNADECITDIRLVFQNCYIFNPPEIDLISMTLTLENIFNSKLDKLPSQE 529
TN+LQ+++ ++ L +H++++PF PVD L + DY K+I PMD T+K RL +Y++A E + D +F NCYI+N P D++ M LE IF K+ ++P +E
Sbjct: 33 TNQLQYMQNVVVKTLWKHQFAWPFYQPVDAIKLCLWDYHKVIKNPMDMGTIKKRLENNYYWSASEAMQDFNTMFTNCYIYNKPTDDIVLMAQALEKIFLQKVAQMPQEE 141 HSP 3 Score: 98.5969 bits (244), Expect = 1.105e-20 Identity = 44/108 (40.74%), Postives = 65/108 (60.19%), Query Frame = 2
Query: 830 KLSEELKMCSNILRDISSNRYRHLNDMFMEPVAVRFPNLSDYSSIIKKPMDLSTIRKNLDDGSYKTKNDFSEDVKLIFDNCYDYNGKDSDISKLAKDLQNIFDELFSK 1153
KL E++K C IL+++ S ++ F +PV L DY IIK PMDLST+RK +D Y F+ DV+L+F NCY YN D ++ +A+ LQ++F+ F+K
Sbjct: 296 KLGEQMKHCDAILKEMLSKKHAAYAWPFYKPVDAEALELHDYHDIIKHPMDLSTVRKKMDKSEYSDPQSFATDVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRFAK 403 HSP 4 Score: 88.5817 bits (218), Expect = 1.413e-17 Identity = 38/101 (37.62%), Postives = 64/101 (63.37%), Query Frame = 2
Query: 233 ILPQLMRHK---YSFPFLHPVDHAALNIPDYPKIIHYPMDFTTVKNRLIKKFYYNADECITDIRLVFQNCYIFNPPEIDLISMTLTLENIFNSKLDKLPSQ 526
IL +++ K Y++PF PVD AL + DY II +PMD +TV+ ++ K Y + TD+RL+F NCY +NPP+ ++++M L+++F + K+P +
Sbjct: 307 ILKEMLSKKHAAYAWPFYKPVDAEALELHDYHDIIKHPMDLSTVRKKMDKSEYSDPQSFATDVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRFAKIPDE 407 HSP 5 Score: 61.2326 bits (147), Expect = 3.733e-9 Identity = 29/75 (38.67%), Postives = 43/75 (57.33%), Query Frame = 2
Query: 911 FMEPVAVRFPNLSDYSSIIKKPMDLSTIRKNLDDGSYKTKNDFSEDVKLIFDNCYDYNGKDSDISKLAKDLQNIF 1135
F +PV L DY +IK PMD+ TI+K L++ Y + ++ +D +F NCY YN DI +A+ L+ IF
Sbjct: 56 FYQPVDAIKLCLWDYHKVIKNPMDMGTIKKRLENNYYWSASEAMQDFNTMFTNCYIYNKPTDDIVLMAQALEKIF 130
BLAST of Bromodomain containing 2 vs. Ensembl Medaka
Match: brd4 (bromodomain-containing protein 4 [Source:NCBI gene;Acc:101158947]) HSP 1 Score: 117.857 bits (294), Expect = 2.679e-26 Identity = 50/109 (45.87%), Postives = 71/109 (65.14%), Query Frame = 2
Query: 203 TNRLQFIKKKILPQLMRHKYSFPFLHPVDHAALNIPDYPKIIHYPMDFTTVKNRLIKKFYYNADECITDIRLVFQNCYIFNPPEIDLISMTLTLENIFNSKLDKLPSQE 529
TN+LQ++ K ++ L +H +S+PF PVD LN+PDY IIH PMD T+K RL +Y+NA ECI D +F NCYI+N P D++ M LE +F K+ ++P +E
Sbjct: 39 TNQLQYLLKVVVKALWKHHFSWPFQAPVDAIKLNLPDYYTIIHTPMDLGTIKKRLENSYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKVFLQKVSEMPQEE 147 HSP 2 Score: 114.775 bits (286), Expect = 2.242e-25 Identity = 49/71 (69.01%), Postives = 63/71 (88.73%), Query Frame = 2
Query: 1685 EDCKPMSYDDKRKLSMDINQLPGDKLGRIVQIIQEREPTLRDSNPDEIEIDFEVLHPVTLRELQKFVQSVL 1897
E CKPM+Y++KR+LS+DIN+LPGDKLGR+V IIQ REP+L++SNPDEIEIDFE L P TLREL+++V + L
Sbjct: 633 EKCKPMTYEEKRQLSLDINKLPGDKLGRVVHIIQSREPSLKNSNPDEIEIDFETLKPSTLRELERYVSTCL 703 HSP 3 Score: 95.9005 bits (237), Expect = 1.357e-19 Identity = 41/109 (37.61%), Postives = 68/109 (62.39%), Query Frame = 2
Query: 827 PKLSEELKMCSNILRDISSNRYRHLNDMFMEPVAVRFPNLSDYSSIIKKPMDLSTIRKNLDDGSYKTKNDFSEDVKLIFDNCYDYNGKDSDISKLAKDLQNIFDELFSK 1153
P+ ++L C+ ++R++ S ++ F +PV V L DY IIK PMDLSTI+ L++ Y+ +F+ DV+L+F NCY YN D ++ +A+ LQ++F+ F+K
Sbjct: 351 PRPQDQLGYCAALVREMLSKKHAAYAWPFYKPVDVDALGLHDYHDIIKHPMDLSTIKAKLENRQYRDPQEFAADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRFAK 459 HSP 4 Score: 87.8113 bits (216), Expect = 4.143e-17 Identity = 35/87 (40.23%), Postives = 57/87 (65.52%), Query Frame = 2
Query: 260 YSFPFLHPVDHAALNIPDYPKIIHYPMDFTTVKNRLIKKFYYNADECITDIRLVFQNCYIFNPPEIDLISMTLTLENIFNSKLDKLP 520
Y++PF PVD AL + DY II +PMD +T+K +L + Y + E D+RL+F NCY +NPP+ ++++M L+++F + K+P
Sbjct: 375 YAWPFYKPVDVDALGLHDYHDIIKHPMDLSTIKAKLENRQYRDPQEFAADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRFAKMP 461 HSP 5 Score: 65.0846 bits (157), Expect = 3.234e-10 Identity = 32/82 (39.02%), Postives = 46/82 (56.10%), Query Frame = 2
Query: 893 RHLNDMFMEPV-AVRFPNLSDYSSIIKKPMDLSTIRKNLDDGSYKTKNDFSEDVKLIFDNCYDYNGKDSDISKLAKDLQNIF 1135
H + F PV A++ NL DY +II PMDL TI+K L++ Y + +D +F NCY YN DI +A+ L+ +F
Sbjct: 56 HHFSWPFQAPVDAIKL-NLPDYYTIIHTPMDLGTIKKRLENSYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKVF 136
BLAST of Bromodomain containing 2 vs. Ensembl Medaka
Match: ENSORLT00000032890.1 (bromodomain-containing protein 2 [Source:NCBI gene;Acc:101162475]) HSP 1 Score: 117.087 bits (292), Expect = 2.714e-26 Identity = 52/115 (45.22%), Postives = 76/115 (66.09%), Query Frame = 2
Query: 185 RPANISTNRLQFIKKKILPQLMRHKYSFPFLHPVDHAALNIPDYPKIIHYPMDFTTVKNRLIKKFYYNADECITDIRLVFQNCYIFNPPEIDLISMTLTLENIFNSKLDKLPSQE 529
RP + TN+LQ+++K ++ L RH++++PF PVD L +PDY KII PMD T+K RL FY +A ECI D +F NCYI+N P+ D++ M +LE IF K+ ++P +E
Sbjct: 67 RPGRM-TNQLQYLQKTLMKCLWRHEFAWPFHEPVDAYRLKLPDYYKIIKQPMDMGTIKKRLENSFYRSASECIQDFNTMFTNCYIYNKPKDDIVLMAQSLEKIFLQKVAQMPQEE 180 HSP 2 Score: 110.923 bits (276), Expect = 1.966e-24 Identity = 59/135 (43.70%), Postives = 86/135 (63.70%), Query Frame = 2
Query: 1511 SKSARQKKPTQESSSNSVPAESNRTETNV---ASSMPATLRMPCNESYQNTELPSKTNRVTEDCKPMSYDDKRKLSMDINQLPGDKLGRIVQIIQEREPTLRDSNPDEIEIDFEVLHPVTLRELQKFVQSVLSRQ 1906
+ S K P + S S A ++ + N +S T++ P N LP + E+ PM+YD+KR+LS+DIN+LPG+KLGR+V IIQ REP+LRD+NP+EIEIDFE L P TL+EL+++V + L ++
Sbjct: 588 AGSEEWKMPGKMMKSKSAKAGGSQPKKNQPKKSSKNSKTVKKPFYPQLSNPILPHYDSEEEEEIVPMTYDEKRQLSLDINKLPGEKLGRVVHIIQSREPSLRDTNPEEIEIDFETLKPSTLKELERYVMTCLRKK 722 HSP 3 Score: 97.8265 bits (242), Expect = 2.457e-20 Identity = 52/139 (37.41%), Postives = 77/139 (55.40%), Query Frame = 2
Query: 737 RKVESCYDLSPTPSPSISLKNESLDEIPIKPKLSEELKMCSNILRDISSNRYRHLNDMFMEPVAVRFPNLSDYSSIIKKPMDLSTIRKNLDDGSYKTKNDFSEDVKLIFDNCYDYNGKDSDISKLAKDLQNIFDELFSK 1153
R+V S + P P L + ++ K KLS L+ CS +L+D+ S ++ F PV L DY IIK PMDLSTI++ +D Y+ F+ DV+L+F NCY YN D D+ +A+ LQ++F+ F+K
Sbjct: 336 RRVGSGRPIKP---PKKDLPDAVQPQLSKKGKLSPPLRYCSGLLKDMLSKKHAAYAWPFYTPVDAAALGLHDYHDIIKCPMDLSTIKRKMDCREYRDAQQFASDVRLMFSNCYKYNPPDHDVVGMARKLQDVFEFSFAK 471 HSP 4 Score: 89.7373 bits (221), Expect = 7.082e-18 Identity = 36/89 (40.45%), Postives = 58/89 (65.17%), Query Frame = 2
Query: 260 YSFPFLHPVDHAALNIPDYPKIIHYPMDFTTVKNRLIKKFYYNADECITDIRLVFQNCYIFNPPEIDLISMTLTLENIFNSKLDKLPSQ 526
Y++PF PVD AAL + DY II PMD +T+K ++ + Y +A + +D+RL+F NCY +NPP+ D++ M L+++F K+P +
Sbjct: 387 YAWPFYTPVDAAALGLHDYHDIIKCPMDLSTIKRKMDCREYRDAQQFASDVRLMFSNCYKYNPPDHDVVGMARKLQDVFEFSFAKMPDE 475 HSP 5 Score: 67.0106 bits (162), Expect = 8.865e-11 Identity = 36/102 (35.29%), Postives = 55/102 (53.92%), Query Frame = 2
Query: 890 YRH-LNDMFMEPVAVRFPNLSDYSSIIKKPMDLSTIRKNLDDGSYKTKNDFSEDVKLIFDNCYDYNGKDSDISKLAKDLQNIF----DELFSKQFNLSKPQP 1180
+RH F EPV L DY IIK+PMD+ TI+K L++ Y++ ++ +D +F NCY YN DI +A+ L+ IF ++ ++ L P P
Sbjct: 87 WRHEFAWPFHEPVDAYRLKLPDYYKIIKQPMDMGTIKKRLENSFYRSASECIQDFNTMFTNCYIYNKPKDDIVLMAQSLEKIFLQKVAQMPQEELELPAPAP 188
BLAST of Bromodomain containing 2 vs. Planmine SMEST
Match: SMESG000075694.1 (SMESG000075694.1) HSP 1 Score: 1201.04 bits (3106), Expect = 0.000e+0 Identity = 662/664 (99.70%), Postives = 663/664 (99.85%), Query Frame = 2
Query: 113 MLVSDDCVEVSQQIDKNVDCSGKPRPANISTNRLQFIKKKILPQLMRHKYSFPFLHPVDHAALNIPDYPKIIHYPMDFTTVKNRLIKKFYYNADECITDIRLVFQNCYIFNPPEIDLISMTLTLENIFNSKLDKLPSQEXXXXXXXXXXXXXXXXXXXXXXXEPVCDIKKSLRPTTKRLKXXXXXXXXXXXXXXXCSISPDAKSKAKKRKVESCYDLSPTPSPSISLKNESLDEIPIKPKLSEELKMCSNILRDISSNRYRHLNDMFMEPVAVRFPNLSDYSSIIKKPMDLSTIRKNLDDGSYKTKNDFSEDVKLIFDNCYDYNGKDSDISKLAKDLQNIFDELFSKQFNLSKPQPSQVQNSKIKSESVNEDTLQLLQKIHKEQKSLVETHNKVAEKIIKQNLLIRELSSTLKIPFEFDLSLINVNSSAVFAXXXXXXXXXXXXXXPIMAKTNGVLNNHVMVSDTMSKSARQKKPTQESSSNSVPAESNRTETNVASSMPATLRMPCNESYQNTELPSKTNRVTEDCKPMSYDDKRKLSMDINQLPGDKLGRIVQIIQEREPTLRDSNPDEIEIDFEVLHPVTLRELQKFVQSVLSRQXXXXXXXXXXXXXGQAGQISEGVITTNTGTEDLASKTKEESRKDSFEDYPNIQGFNNQPKGETGAA 2104
MLVSDDCVEVSQQIDKNVDCSGKPRPANISTNRLQFIKKKILPQLMRHKYSFPFLHPVDHAALNIPDYPKIIHYPMDFTTVKNRLIKKFYYNADECITDIRLVFQNCYIFNPPEIDLISMTLTLENIFNSKLDKLPSQENDISSSNSKKDTKSNSINNDSSSEPVCDIKKSLRPTTKRLKSNSNYNETTSTNASNCSISPDAKSKAKKRKVESCYDLSPTPSPSISLKNESLDEIPIKPKLSEELKMCSNILRDISSNRYRHLNDMFMEPVAVRFPNLSDYSSIIKKPMDLSTIRKNLDDGSYKTKNDFSEDVKLIFDNCYDYNGKDSDISKLAKDLQNIFDELFSKQFNLSKPQP QVQNSKIKSESVNEDTLQLLQKIHKEQKSLVETHNKVAEKIIKQNLLIRELSSTLKIPFEFDLSLINVNSSAVFANSKSKKRNKNLSPSPIMAKTNGVLNNHVMVSDTMSKSARQKKPTQESSSNSVPAESNRTETNVASSMPATLRMPCNESYQNTELPSKTNRVTEDCKPMSYDDKRKLSMDINQLPGDKLGRIVQIIQEREPTLRDSNPDEIEIDFEVLHPVTLRELQKFVQSVLSRQKSNTSKKSAKKSNGQAGQISEGVITTN+GTEDLASKTKEESRKDSFEDYPNIQGFNNQPKGETGAA
Sbjct: 1 MLVSDDCVEVSQQIDKNVDCSGKPRPANISTNRLQFIKKKILPQLMRHKYSFPFLHPVDHAALNIPDYPKIIHYPMDFTTVKNRLIKKFYYNADECITDIRLVFQNCYIFNPPEIDLISMTLTLENIFNSKLDKLPSQENDISSSNSKKDTKSNSINNDSSSEPVCDIKKSLRPTTKRLKSNSNYNETTSTNASNCSISPDAKSKAKKRKVESCYDLSPTPSPSISLKNESLDEIPIKPKLSEELKMCSNILRDISSNRYRHLNDMFMEPVAVRFPNLSDYSSIIKKPMDLSTIRKNLDDGSYKTKNDFSEDVKLIFDNCYDYNGKDSDISKLAKDLQNIFDELFSKQFNLSKPQPFQVQNSKIKSESVNEDTLQLLQKIHKEQKSLVETHNKVAEKIIKQNLLIRELSSTLKIPFEFDLSLINVNSSAVFANSKSKKRNKNLSPSPIMAKTNGVLNNHVMVSDTMSKSARQKKPTQESSSNSVPAESNRTETNVASSMPATLRMPCNESYQNTELPSKTNRVTEDCKPMSYDDKRKLSMDINQLPGDKLGRIVQIIQEREPTLRDSNPDEIEIDFEVLHPVTLRELQKFVQSVLSRQKSNTSKKSAKKSNGQAGQISEGVITTNSGTEDLASKTKEESRKDSFEDYPNIQGFNNQPKGETGAA 664
BLAST of Bromodomain containing 2 vs. Planmine SMEST
Match: SMESG000040270.1 (SMESG000040270.1) HSP 1 Score: 182.185 bits (461), Expect = 2.611e-47 Identity = 95/222 (42.79%), Postives = 148/222 (66.67%), Query Frame = 2
Query: 743 VESCYDLSPTPSPSI---SLKNESLDEIPIK-PKLSEELKMCSNILRDISSNRYRHLNDMFMEPVAVRFPNLSDYSSIIKKPMDLSTIRKNLDDGSYKTKNDFSEDVKLIFDNCYDYNGKDSDISKLAKDLQNIFDELFSKQFNLSKPQPSQVQNSKIKSES----VNEDTLQLLQKIHKEQKSLVETHNKVAEKIIKQNLLIRELSSTLKIPFEFDLSLIN 1384
++SCYD+SPTPSP I LK+E D+ +K P+LS++L++C+ +L++I + RYRHLN+MF+EPV +FP+L DY SIIK P+DL TI+ L++ YKTK++F DV+L+F+NCY YNG +SD+S+LA+DLQ IFDE +SKQF L+ + S+ ++S +N D + KE + LV + ++ + +R +++TL +P E D ++
Sbjct: 180 IDSCYDMSPTPSPPIFKSKLKSEFSDDHHLKRPRLSDDLRLCAALLKEIMAVRYRHLNEMFLEPVTQKFPSLKDYLSIIKNPIDLGTIKDKLENYQYKTKDEFLNDVQLMFNNCYAYNGMESDVSRLARDLQKIFDEAYSKQFKLNSSKSLLTTKSEPTAKSDPVVINIDPKVTFMALQKEYRELVNS-------VVSFDQKLRGMAATLNLPHEPDGGILG 394 HSP 2 Score: 120.939 bits (302), Expect = 9.702e-28 Identity = 52/117 (44.44%), Postives = 82/117 (70.09%), Query Frame = 2
Query: 179 KPRPANISTNRLQFIKKKILPQLMRHKYSFPFLHPVDHAALNIPDYPKIIHYPMDFTTVKNRLIKKFYYNADECITDIRLVFQNCYIFNPPEIDLISMTLTLENIFNSKLDKLPSQE 529
K +PA I TN+L++IKK+I+P ++++ +++PF VD+ LN+PDYP+II PMD + +K RL +K+Y A +CI D+ +F NCYI+NPP D+++M LE + KL +P +E
Sbjct: 14 KVKPAKILTNKLEYIKKQIIPVILKNPHAYPFAKAVDYINLNLPDYPEIIKGPMDISKIKVRLAQKYYRRASDCIQDLFQIFCNCYIYNPPGTDIVNMARALEILTREKLKMMPIEE 130 HSP 3 Score: 109.383 bits (272), Expect = 4.053e-24 Identity = 60/112 (53.57%), Postives = 76/112 (67.86%), Query Frame = 2
Query: 1565 PAESNRTETNVASSMPATLRMPCNESYQNTELPSKTNRVTEDCKPMSYDDKRKLSMDINQLPGDKLGRIVQIIQEREPTLRDSNPDEIEIDFEVLHPVTLRELQKFVQSVLS 1900
PA+ + + ++ P T+R P + + Q P KT MSY+DKR+LSM IN LPGDKLGR+VQIIQEREP RDSN DE+EIDFE+L P TL EL++FVQS L+
Sbjct: 604 PAQHHHNDEQLSPFPPGTIR-PTDPAEQQ---PIKT---------MSYEDKRQLSMHINDLPGDKLGRVVQIIQEREPAHRDSNMDELEIDFELLQPETLLELERFVQSTLA 702 HSP 4 Score: 59.3066 bits (142), Expect = 1.522e-8 Identity = 33/96 (34.38%), Postives = 50/96 (52.08%), Query Frame = 2
Query: 227 KKILPQLMRHKYSFPFLHPVDHAALNIPDYPKIIHYPMDFTTVKNRLIKKFYYNADECITDIRLVFQNCYIFNPPEIDLISMTLTLENIFNSKLDK 514
K+I+ RH FL PV ++ DY II P+D T+K++L Y DE + D++L+F NCY +N E D+ + L+ IF+ K
Sbjct: 226 KEIMAVRYRHLNEM-FLEPVTQKFPSLKDYLSIIKNPIDLGTIKDKLENYQYKTKDEFLNDVQLMFNNCYAYNGMESDVSRLARDLQKIFDEAYSK 320 HSP 5 Score: 53.5286 bits (127), Expect = 7.364e-7 Identity = 27/62 (43.55%), Postives = 37/62 (59.68%), Query Frame = 2
Query: 941 NLSDYSSIIKKPMDLSTIRKNLDDGSYKTKNDFSEDVKLIFDNCYDYNGKDSDISKLAKDLQ 1126
NL DY IIK PMD+S I+ L Y+ +D +D+ IF NCY YN +DI +A+ L+
Sbjct: 55 NLPDYPEIIKGPMDISKIKVRLAQKYYRRASDCIQDLFQIFCNCYIYNPPGTDIVNMARALE 116
BLAST of Bromodomain containing 2 vs. Planmine SMEST
Match: SMESG000005406.1 (SMESG000005406.1) HSP 1 Score: 180.259 bits (456), Expect = 4.003e-47 Identity = 137/401 (34.16%), Postives = 200/401 (49.88%), Query Frame = 2
Query: 833 LSEELKMCSNILRDISSNRYRHLNDMFMEPVAVRFPNLSDYSSIIKKPMDLSTIRKNLDDGSYKTKNDFSEDVKLIFDNCYDYNGKDSDISKLAKDLQNIFDELFSKQFNLSKP--------------QPSQVQNSKIKSESV----------------------NEDTLQLLQKIHKEQKSLVETHNKVAEKIIKQNLLIRELSSTLKIPFEFDLSLINVNSSA----------VFAXXXXXXXXXXXXXXPIMAKTNGVLNNHVMVSDTMSKSARQKKPTQESSSNSVPAESNRTETNVASSMPATLRMPCNESYQNTELPSKTNRVTEDCKPMSYDDKRKLSMDINQLPGDKLGRIVQIIQEREPTLRDSNPDEIEIDFEVLHPVTLRELQKFVQSVL 1897
L+ +L C NIL+DI S++YR LN +F+ PV V+ NL +Y IIKKPMD +TI+ L+ Y+ K F EDV+L+F+NC +NG+ + +K+AK L IF EL +K F+ +K + S + K K ESV ++ +Q L KI Q L++ KV E + Q I EL LK + SL+ NS+ + + N+ I+ LN + + S ++ + + P + V SS L N + N + S+ V E PM Y++KR+L ++INQL DKLGR+V+IIQE EPTLRDS+PDE+E+DFE+L TLR+L+K+V SVL
Sbjct: 187 LNSDLSKCLNILKDIMSSKYRKLNGLFLLPVDVKKYNLHNYFEIIKKPMDFTTIKSKLEANLYENKEKFIEDVELVFNNCTIFNGELHEYAKIAKTLNEIFKELCTKTFSTNKTAETLQTSFKPDSNERNSFINQIKSKDESVLKSSPQEIHIPIDRSQISDNLDKKEIIQRLFKIESLQDELMQESRKVQELMTIQGAEIDELHQKLK-----EKSLLTCNSTGDKINPADTNNIGEFCDAGSMMSNMKSKRIIHPPKNKLNETINTPQSASGRKSSISSSKINPRKNAPDSCKKVTAPVKSS--KGLFPNENAAISNIKCKSEEEEVYE---PMIYEEKRQLRLNINQLLSDKLGRVVEIIQENEPTLRDSDPDEMEVDFEILQTKTLRKLEKYVNSVL 577 HSP 2 Score: 118.242 bits (295), Expect = 4.338e-27 Identity = 54/105 (51.43%), Postives = 73/105 (69.52%), Query Frame = 2
Query: 203 TNRLQFIKKKILPQLMRHKYSFPFLHPVDHAALNIPDYPKIIHYPMDFTTVKNRLIKKFYYNADECITDIRLVFQNCYIFNPPEIDLISMTLTLENIFNSKLDKL 517
TN L++I K +LP L++HK+++PF VD ALNIPDYPKII PMDF+ VK++L K Y + ECI D+ VF NCY+FN P D+I M L L++IF K+ +
Sbjct: 9 TNSLEYINKTVLPSLLKHKFAWPFTKAVDIVALNIPDYPKIIRQPMDFSLVKSKLRNKQYSSIYECIDDVNRVFCNCYLFNQPGEDVIFMALKLDSIFKEKIKHM 113 HSP 3 Score: 66.6254 bits (161), Expect = 6.577e-11 Identity = 38/91 (41.76%), Postives = 51/91 (56.04%), Query Frame = 2
Query: 233 ILPQLMRHKY---SFPFLHPVDHAALNIPDYPKIIHYPMDFTTVKNRLIKKFYYNADECITDIRLVFQNCYIFNPPEIDLISMTLTLENIF 496
IL +M KY + FL PVD N+ +Y +II PMDFTT+K++L Y N ++ I D+ LVF NC IFN + + TL IF
Sbjct: 197 ILKDIMSSKYRKLNGLFLLPVDVKKYNLHNYFEIIKKPMDFTTIKSKLEANLYENKEKFIEDVELVFNNCTIFNGELHEYAKIAKTLNEIF 287 HSP 4 Score: 51.6026 bits (122), Expect = 3.093e-6 Identity = 26/77 (33.77%), Postives = 42/77 (54.55%), Query Frame = 2
Query: 911 FMEPVAVRFPNLSDYSSIIKKPMDLSTIRKNLDDGSYKTKNDFSEDVKLIFDNCYDYNGKDSDISKLAKDLQNIFDE 1141
F + V + N+ DY II++PMD S ++ L + Y + + +DV +F NCY +N D+ +A L +IF E
Sbjct: 32 FTKAVDIVALNIPDYPKIIRQPMDFSLVKSKLRNKQYSSIYECIDDVNRVFCNCYLFNQPGEDVIFMALKLDSIFKE 108
BLAST of Bromodomain containing 2 vs. Planmine SMEST
Match: SMESG000080341.1 (SMESG000080341.1) HSP 1 Score: 165.236 bits (417), Expect = 3.195e-44 Identity = 115/379 (30.34%), Postives = 188/379 (49.60%), Query Frame = 2
Query: 170 CSGKPRPANISTNRLQFIKKKILPQLMRHKYSFPFLHPVDHAALNIPDYPKIIHYPMDFTTVKNRLIKKFYYNADECITDIRLVFQNCYIFNPPEIDLISMTLTLENIFNSKLDKLPSQEXXXXXXXXXXXXXXXXXXXXXXXEPVCDIKKSLRPTTKRLKXXXXXXXXXXXXXXXCSISPDAKSKAKKRKVESCYDLSPTPSPSISLKNESLDEIPIKPKLSEELKMCSNILRDISSNRYRHLNDMFMEPVAVRFPNLSDYSSIIKKPMDLSTIRKNLDDGSYKTKNDFSEDVKLIFDNCYDYNGKDSDISKLAKDLQNIFDELFSKQFNLSKPQPSQVQNSKIKSESVNEDTLQLLQKIHKEQKSLVETHNKVAEKI 1306
C KP TN+L + KKI+P +MR++ + PFL PVDH A +PDYP++I P+D +T+K RLI+KFY +C+ D L+ +NCYI+N P+ +ISM + L+ +KL +P E V ++K + P K+ +K K+++ ++S +P IS S + IP+ E C ++ ++ S++Y+ +N +F+EPV V+ LSDY +IK P+DLSTI+K +D+ Y ++ D+ L+ +NC YNG+ +DI + + Q F+ L+ F K + E+VN++ L KI ++ K + E +EKI
Sbjct: 6 CPQKP-----FTNKLDIMLKKIIPFVMRYEAAKPFLKPVDHVAYQLPDYPQVIKSPIDLSTIKERLIRKFYETLGKCLQDFNLMLENCYIYNAPDDPIISMGIKLKLYLKAKLVLMPIDEFK-----------------------VKNLKNKIVPLR------------------------SVKTPKQKLKIKNFLNVSQSPVKKISENIVSSNYIPLT---DSEYGKCYILINELMSSKYKSINYLFLEPVDVKSLGLSDYHELIKYPIDLSTIQKYMDERLYDSRLAVVNDIYLMINNCNIYNGRQTDIGNICRRFQLEFENLYYSIF-----------KEKCR-ENVNDEAFYFLMKIKRKHKEIEEMIRINSEKI 317
BLAST of Bromodomain containing 2 vs. Planmine SMEST
Match: SMESG000080341.1 (SMESG000080341.1) HSP 1 Score: 161.384 bits (407), Expect = 9.131e-44 Identity = 110/362 (30.39%), Postives = 181/362 (50.00%), Query Frame = 2
Query: 227 KKILPQLMRHKYSFPFLHPVDHAALNIPDYPKIIHYPMDFTTVKNRLIKKFYYNADECITDIRLVFQNCYIFNPPEIDLISMTLTLENIFNSKLDKLPSQEXXXXXXXXXXXXXXXXXXXXXXXEPVCDIKKSLRPTTKRLKXXXXXXXXXXXXXXXCSISPDAKSKAKKRKVESCYDLSPTPSPSISLKNESLDEIPIKPKLSEELKMCSNILRDISSNRYRHLNDMFMEPVAVRFPNLSDYSSIIKKPMDLSTIRKNLDDGSYKTKNDFSEDVKLIFDNCYDYNGKDSDISKLAKDLQNIFDELFSKQFNLSKPQPSQVQNSKIKSESVNEDTLQLLQKIHKEQKSLVETHNKVAEKIIK 1312
KKI+P +MR++ + PFL PVDH A +PDYP++I P+D +T+K RLI+KFY +C+ D L+ +NCYI+N P+ +ISM + L+ +KL +P E V ++K + P K+ +K K+++ ++S +P IS S + IP+ E C ++ ++ S++Y+ +N +F+EPV V+ LSDY +IK P+DLSTI+K +D+ Y ++ D+ L+ +NC YNG+ +DI + + Q F+ L+ F K + E+VN++ L KI ++ K + E +KV I K
Sbjct: 3 KKIIPFVMRYEAAKPFLKPVDHVAYQLPDYPQVIKSPIDLSTIKERLIRKFYETLGKCLQDFNLMLENCYIYNAPDDPIISMGIKLKLYLKAKLVLMPIDEFK-----------------------VKNLKNKIVPLR------------------------SVKTPKQKLKIKNFLNVSQSPVKKISENIVSSNYIPLT---DSEYGKCYILINELMSSKYKSINYLFLEPVDVKSLGLSDYHELIKYPIDLSTIQKYMDERLYDSRLAVVNDIYLMINNCNIYNGRQTDIGNICRRFQLEFENLYYSIF-----------KEKCR-ENVNDEAFYFLMKIKRKHKEIEEMIDKVVAIIWK 302 The following BLAST results are available for this feature:
BLAST of Bromodomain containing 2 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of Bromodomain containing 2 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of Bromodomain containing 2 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of Bromodomain containing 2 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of Bromodomain containing 2 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of Bromodomain containing 2 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of Bromodomain containing 2 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of Bromodomain containing 2 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Bromodomain containing 2 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of Bromodomain containing 2 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 5
BLAST of Bromodomain containing 2 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 4
BLAST of Bromodomain containing 2 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of Bromodomain containing 2 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of Bromodomain containing 2 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30028894 ID=SMED30028894|Name=Bromodomain containing 2|organism=Schmidtea mediterranea sexual|type=transcript|length=2927bpback to top protein sequence of SMED30028894-orf-1 >SMED30028894-orf-1 ID=SMED30028894-orf-1|Name=SMED30028894-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=692bp MLVSDDCVEVSQQIDKNVDCSGKPRPANISTNRLQFIKKKILPQLMRHKYback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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