Transmembrane emp24 domain-containing protein 10

Overview
NameTransmembrane emp24 domain-containing protein 10
Smed IDSMED30028888
Length (bp)1116
Neoblast Clusters

Zeng et. al., 2018




▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 



 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)




Explore this single cell expression dataset with our NB Cluster Shiny App




 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Transmembrane emp24 domain-containing protein 10 (SMED30028888) t-SNE clustered cells

Violin plots show distribution of expression levels for Transmembrane emp24 domain-containing protein 10 (SMED30028888) in cells (dots) of each of the 12 neoblast clusters.

 

back to top


 

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Transmembrane emp24 domain-containing protein 10 (SMED30028888) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Transmembrane emp24 domain-containing protein 10 (SMED30028888) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

back to top


 

Embryonic Expression

Davies et. al., 2017




Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

back to top
Anatomical Expression

PAGE et. al., 2020




SMED30028888

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 9

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
epidermisSMED30028888SMESG000024933.1 dd_Smed_v4_746_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30028888SMESG000024933.1 dd_Smed_v4_746_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
muscle cellSMED30028888SMESG000024933.1 dd_Smed_v4_746_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
neoblastSMED30028888SMESG000024933.1 dd_Smed_v4_746_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymal cellSMED30028888SMESG000024933.1 dd_Smed_v4_746_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30028888SMESG000024933.1 Contig35445uc_Smed_v2PMID:29674431
Fincher et al., 2018
FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30028888SMESG000024933.1 Contig35445newmark_estsPMID:29674431
Fincher et al., 2018
FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Category 2 cellSMED30028888SMESG000024933.1 dd_Smed_v6_746_0dd_Smed_v6PMID:29674432
Plass et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Category 3 cellSMED30028888SMESG000024933.1 dd_Smed_v6_746_0dd_Smed_v6PMID:29674432
Plass et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
BLAST of Transmembrane emp24 domain-containing protein 10 vs. Ensembl Human
Match: TMED10 (transmembrane p24 trafficking protein 10 [Source:HGNC Symbol;Acc:HGNC:16998])

HSP 1 Score: 250.751 bits (639), Expect = 5.123e-82
Identity = 121/192 (63.02%), Postives = 154/192 (80.21%), Query Frame = 1
Query:  121 AIRFFVTPNGGKKCLKEEIHKNVLVTGEYDITD----APGQKASIQVTDSKSHVLYQKDDISKGKFAFTTEEYEMFDVCVETKLMGGGKGPDREVFLDIKHGVETKNYDSLAQAEKLKPLEVELKRLEDLSDEIVKDFQYMRDREEKMRDTNESTHNRVFYFSIFSMGCLMALAVWQVLYLRRYFKSKKLIE 684
            AI F + P   +KCL+EEIHK++LVTG Y+I+D    A G ++ +++TDS  H+LY K+D +KGKFAFTTE+Y+MF+VC E+K  G G+ PD+ V LD+KHGVE KNY+ +A+ EKLKPLEVEL+RLEDLS+ IV DF YM+ REE+MRDTNEST+ RV YFSIFSM CL+ LA WQV YLRR+FK+KKLIE
Sbjct:   31 AISFHL-PINSRKCLREEIHKDLLVTGAYEISDQSGGAGGLRSHLKITDSAGHILYSKEDATKGKFAFTTEDYDMFEVCFESK--GTGRIPDQLVILDMKHGVEAKNYEEIAKVEKLKPLEVELRRLEDLSESIVNDFAYMKKREEEMRDTNESTNTRVLYFSIFSMFCLIGLATWQVFYLRRFFKAKKLIE 219          
BLAST of Transmembrane emp24 domain-containing protein 10 vs. Ensembl Human
Match: TMED10 (transmembrane p24 trafficking protein 10 [Source:HGNC Symbol;Acc:HGNC:16998])

HSP 1 Score: 122.865 bits (307), Expect = 2.351e-33
Identity = 61/116 (52.59%), Postives = 87/116 (75.00%), Query Frame = 1
Query:  121 AIRFFVTPNGGKKCLKEEIHKNVLVTGEYDITD----APGQKASIQVTDSKSHVLYQKDDISKGKFAFTTEEYEMFDVCVETKLMGGGKGPDREVFLDIKHGVETKNYDSLAQAEK 456
            AI F + P   +KCL+EEIHK++LVTG Y+I+D    A G ++ +++TDS  H+LY K+D +KGKFAFTTE+Y+MF+VC E+K  G G+ PD+ V LD+KHGVE KNY+  + +E+
Sbjct:   31 AISFHL-PINSRKCLREEIHKDLLVTGAYEISDQSGGAGGLRSHLKITDSAGHILYSKEDATKGKFAFTTEDYDMFEVCFESK--GTGRIPDQLVILDMKHGVEAKNYEEHSVSEE 143          
BLAST of Transmembrane emp24 domain-containing protein 10 vs. Ensembl Human
Match: TMED9 (transmembrane p24 trafficking protein 9 [Source:HGNC Symbol;Acc:HGNC:24878])

HSP 1 Score: 102.064 bits (253), Expect = 1.092e-24
Identity = 63/215 (29.30%), Postives = 108/215 (50.23%), Query Frame = 1
Query:   85 SLFILNFLYITSAIRFFVTPNGGKKCLKEEIHKNVLVTGEYDI-----------TDAPGQKASIQVTDSKSHVLYQKDDISKGKFAFTTEEYEMFDVCVETK-----LMGGGKGPDREVFLDIKHGVETKNYDSLAQAEKLKPLEVELKRLEDLSDEIVKDFQYMRDREEKMRDTNESTHNRVFYFSIFSMGCLMALAVWQVLYLRRYFKSKKLI 681
            +L ++ +L    +  +F      KKC  EEI    +V G Y                PG    ++V D +  V+  +   S+G+F FT+       +C+ +      L  GG      V LDI+ G    +Y  +A  +KL  L++ +++L +  ++I K+  Y R REE+ R T+EST+ RV ++SI     L+A+ VWQ+ +L+ +F++KKL+
Sbjct:   24 TLLLVLWLATRGSALYFHIGETEKKCFIEEIPDETMVIGNYRTQLYDKQREEYQPATPGLGMFVEVKDPEDKVILARQYGSEGRFTFTSHTPGEHQICLHSNSTKFSLFAGGM---LRVHLDIQVGEHANDYAEIAAKDKLSELQLRVRQLVEQVEQIQKEQNYQRWREERFRQTSESTNQRVLWWSILQTLILVAIGVWQMRHLKSFFEAKKLV 235          
BLAST of Transmembrane emp24 domain-containing protein 10 vs. Ensembl Human
Match: TMED4 (transmembrane p24 trafficking protein 4 [Source:HGNC Symbol;Acc:HGNC:22301])

HSP 1 Score: 99.3673 bits (246), Expect = 1.069e-23
Identity = 60/192 (31.25%), Postives = 97/192 (50.52%), Query Frame = 1
Query:  154 KKCLKEEIHKNVLVTGEYD-----------ITDAPGQKASIQVTDSKSHVLYQKDDISKGKFAFTTEEYEMFDVCVETK-----LMGGGKGPDREVFLDIKHGVETKNYDSLAQAEKLKPLEVELKRLEDLSDEIVKDFQYMRDREEKMRDTNESTHNRVFYFSIFSMGCLMALAVWQVLYLRRYFKSKKLI 681
            K+C  EEI    +V G Y            +   PG    ++V D    V+  +   S+G+F FT+       +C+ +      L  GGK     V LDI+ G    NY  +A  +KL  L++  ++L D  ++I K+  Y R REE+ R T+EST+ RV ++SI     L+   +WQ+ +L+ +F++KKL+
Sbjct:   39 KRCFIEEIPDETMVIGNYRTQMWDKQKEVFLPSTPGLGMHVEVKDPDGKVVLSRQYGSEGRFTFTSHTPGDHQICLHSNSTRMALFAGGK---LRVHLDIQVGEHANNYPEIAAKDKLTELQLRARQLLDQVEQIQKEQDYQRYREERFRLTSESTNQRVLWWSIAQTVILILTGIWQMRHLKSFFEAKKLV 227          
BLAST of Transmembrane emp24 domain-containing protein 10 vs. Ensembl Human
Match: TMED4 (transmembrane p24 trafficking protein 4 [Source:HGNC Symbol;Acc:HGNC:22301])

HSP 1 Score: 56.6102 bits (135), Expect = 6.906e-9
Identity = 40/143 (27.97%), Postives = 63/143 (44.06%), Query Frame = 1
Query:  154 KKCLKEEIHKNVLVTGEYD-----------ITDAPGQKASIQVTDSKSHVLYQKDDISKGKFAFTTEEYEMFDVCVETK-----LMGGGKGPDREVFLDIKHGVETKNYDSLAQAEKLKPLEVELKRLEDLSDEIVKDFQYMR 534
            K+C  EEI    +V G Y            +   PG    ++V D    V+  +   S+G+F FT+       +C+ +      L  GGK     V LDI+ G    NY  +A  +KL  L++  ++L D  ++I K+  Y R
Sbjct:   39 KRCFIEEIPDETMVIGNYRTQMWDKQKEVFLPSTPGLGMHVEVKDPDGKVVLSRQYGSEGRFTFTSHTPGDHQICLHSNSTRMALFAGGK---LRVHLDIQVGEHANNYPEIAAKDKLTELQLRARQLLDQVEQIQKEQDYQR 178          
BLAST of Transmembrane emp24 domain-containing protein 10 vs. Ensembl Celegans
Match: F47G9.1 (pep chromosome:WBcel235:V:11323965:11326964:-1 gene:WBGene00009829.1 transcript:F47G9.1.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:F47G9.1)

HSP 1 Score: 245.743 bits (626), Expect = 1.395e-80
Identity = 116/201 (57.71%), Postives = 154/201 (76.62%), Query Frame = 1
Query:   88 LFILNFLYITSAIRFFVTPNGGKKCLKEEIHKNVLVTGEYDITDAPGQKASIQVTDSKSHVLYQKDDIS--KGKFAFTTEEYEMFDVCVETKLMGGGKGPDREVFLDIKHGVETKNYDSLAQAEKLKPLEVELKRLEDLSDEIVKDFQYMRDREEKMRDTNESTHNRVFYFSIFSMGCLMALAVWQVLYLRRYFKSKKLIE 684
            +  L+ + +  ++RF+V P   KKCLKEEIHKNV+VTGEY+ +       SI VTD++ H LY++++ +  KGKFAFT +EY++F++C+E     G  G  REV L +KHGVE KNYD +A+AEKLKPLEVEL+RLED++D I KDF +MR REE+MR+TNEST++RV Y SIFSM CL+ LA+WQVL+LR YFKSKKLI+
Sbjct:    5 VIFLSAIVLAHSLRFYVPPKE-KKCLKEEIHKNVVVTGEYEFSQGIQYTGSIHVTDTRGHTLYKRENFADLKGKFAFTADEYDIFEICIENHPPAGHPGEKREVSLILKHGVEAKNYDDIAKAEKLKPLEVELRRLEDMADSITKDFAFMRQREEEMRNTNESTNSRVLYLSIFSMLCLLGLAIWQVLFLRNYFKSKKLID 204          
BLAST of Transmembrane emp24 domain-containing protein 10 vs. Ensembl Celegans
Match: Y60A3A.9 (pep chromosome:WBcel235:V:19946691:19949093:-1 gene:WBGene00013360.1 transcript:Y60A3A.9.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:Y60A3A.9)

HSP 1 Score: 114.775 bits (286), Expect = 5.472e-30
Identity = 64/194 (32.99%), Postives = 102/194 (52.58%), Query Frame = 1
Query:  130 FFVTPNGGKKCLKEEIHKNVLVTGEYDIT----------DAPGQKASIQVTDSKSHVLYQKDDISKGKFAFTTEEYEMFDVCVETKLMGGGKGPDREVFLDIKHGVETKNYDSLAQAEKLKPLEVELKRLEDLSDEIVKDFQYMRDREEKMRDTNESTHNRVFYFSIFSMGCLMALAVWQVLYLRRYFKSKKLI 681
            +F      KKC  EEI    +VTG Y +           D P     ++V D +  V+  K   ++G+F FT+       +C+ +       G    V LDI+ G   ++Y  +AQ +KL  L++ +++L D  D+I K+  Y R REE+ R T+EST++RVFY+SI  +  L     WQ+ +LR +F++KKL+
Sbjct:   18 YFHIAETEKKCFIEEIPDETMVTGNYKVQLYDPNTKGYGDYPNIGMHVEVKDPEDKVILSKLYTAEGRFTFTSNTPGEHVICIYSNSTAWFNGAQLRVHLDIQAGDHAQDYAQIAQKDKLNELQLRIRQLLDQVDQITKEQNYQRYREERFRQTSESTNSRVFYWSIAQVVVLAITGAWQMRHLRGFFEAKKLV 211          
BLAST of Transmembrane emp24 domain-containing protein 10 vs. Ensembl Celegans
Match: sel-9 (Suppressor/enhancer of lin-12 protein 9 [Source:UniProtKB/Swiss-Prot;Acc:O17528])

HSP 1 Score: 55.4546 bits (132), Expect = 7.473e-9
Identity = 42/205 (20.49%), Postives = 89/205 (43.41%), Query Frame = 1
Query:   91 FILNFLYITSAIRFFVTPNGGK-KCLKEEIHKNVLVTGEYDITDAPGQKASIQVTDSKSHVLYQKDDISKGKFAFTTEEYEMFDVCVETKLMGGGKGPDREVFLDIKHGVETKNYDSLAQAEKLKPLEVELKRLEDLSDEIVKDF-------QYMRDREEKMRDTNESTHNRVFYFSIFSMGCLMALAVWQVLYLRRYFKSKKLI 681
            +IL  L++T A  +F+  +  + +C  + +     +   +++ +       +++T   +  +Y+ +  S GKF F      ++  C   K+      P   +F      VE       A          +  +LE++  E+           +YM  RE   R+ NE+T++RV  ++ F    L+ + V Q+ YL+R+F+ + ++
Sbjct:    6 WILAVLFVTPAASYFIHVDANEEQCFFDRLTSGTKMGLMFEVAEGGFLDIDVKITGPDNKEIYKGERESSGKFTFAAHMDGVYTYCFGNKM--STMTPKAVMFT-----VEITEPHQQAPGAAANQDAADNAKLEEMVRELSSALMSVKHEQEYMEVRERVHRNINENTNSRVVMWAAFEAFVLVGMTVGQIFYLKRFFEVRTMV 203          
BLAST of Transmembrane emp24 domain-containing protein 10 vs. Ensembl Celegans
Match: T08D2.1 (pep chromosome:WBcel235:X:162529:163134:-1 gene:WBGene00011606.1 transcript:T08D2.1.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:T08D2.1)

HSP 1 Score: 48.521 bits (114), Expect = 1.084e-6
Identity = 38/135 (28.15%), Postives = 56/135 (41.48%), Query Frame = 1
Query:  130 FFVTPNGGKKCLKEEIHKNVLVTGEYDIT----------DAPGQKASIQVTDSKSHVLYQKDDISKGKFAFTTEEYEMFDVCVETKLMGGGKGPDREVFLDIKHGVETKNYDSLAQAEKL-----KPLEVELKRL 489
            +F      KKC  EEI    +VTG Y +           D P     ++V D +  V+  K   S+G+F FT+       +C+ +       G    V LDI+ G   ++Y  + +  KL     K LE E  RL
Sbjct:   18 YFHIAETEKKCFIEEIPDETMVTGNYKVQLYDPNTKGYGDYPNIGMHVEVKDPEDKVILSKLYTSEGRFTFTSNTPGEHVICIYSNTTAWFNGAQLRVHLDIQAGDHAQDYAQVEEERKLDENREKSLENEDFRL 152          
BLAST of Transmembrane emp24 domain-containing protein 10 vs. Ensembl Fly
Match: bai (gene:FBgn0045866 transcript:FBtr0084758)

HSP 1 Score: 224.172 bits (570), Expect = 4.975e-72
Identity = 108/201 (53.73%), Postives = 147/201 (73.13%), Query Frame = 1
Query:   82 ISLFILNFLYITSAIRFFVTPNGGKKCLKEEIHKNVLVTGEYDITDAPGQKASIQVTDSKSHVLYQKDDISKGKFAFTTEEYEMFDVCVETKLMGGGKGPDREVFLDIKHGVETKNYDSLAQAEKLKPLEVELKRLEDLSDEIVKDFQYMRDREEKMRDTNESTHNRVFYFSIFSMGCLMALAVWQVLYLRRYFKSKKLIE 684
            I   ++   + + A+ F ++PN  +KCLKE+I  N LV GE++++D PGQ       D+K H+L QK+ I+KGKF+F +E Y+ +++C  +K+    +G  +EV L  K GVETK+Y+ + +A KLKPLEV+LKRLEDLSD IV+DF  MR REE+MRDTNE T++RV +FSIFSM CL+ LA WQVLYLRRYFK+KKLIE
Sbjct:    7 IVCLLMACAWSSHAVMFKLSPNT-QKCLKEDIQANQLVMGEFEVSDVPGQIIDYIARDTKGHILSQKEHITKGKFSFMSEVYDTYEICFISKVPAHQRGVIQEVSLLTKKGVETKSYEGIGEASKLKPLEVDLKRLEDLSDSIVRDFVLMRKREEEMRDTNEKTNSRVLFFSIFSMCCLLGLATWQVLYLRRYFKAKKLIE 206          
BLAST of Transmembrane emp24 domain-containing protein 10 vs. Ensembl Fly
Match: eca (gene:FBgn0069242 transcript:FBtr0082098)

HSP 1 Score: 98.5969 bits (244), Expect = 7.668e-24
Identity = 61/212 (28.77%), Postives = 108/212 (50.94%), Query Frame = 1
Query:   82 ISL-FILNFLYITSAIRFFVTPNGGKKCLKEEIHKNVLVTGEYDI-----------TDAPGQKASIQVTDSKSHVLYQKDDISKGKFAFTTEEYEMFDVCVETKLMGGGKGPDREVFLDIKHGVETKNYDSLAQAEKLKPLEVELKRLEDLSDEIVKDFQYMRDREEKMRDTNESTHNRVFYFSIFSMGCLMALAVWQVLYLRRYFKSKKLI 681
            ISL  IL  L+    + F ++    +KC  EE+     V   Y +             +PG    ++V DS   ++  +   S+G+ +FT+       +C+ +       G    V LDI+ G    +Y  +AQ EKL  L++ +++L D  ++I K+  Y R REE+ R T+EST++RV ++S+     L+ +  WQ+ +L+ +F++KKL+
Sbjct:    6 ISLALILCVLHSACGLYFHISETE-RKCFIEEVPDETTVIVNYKVELYDPRSNGFMPSSPGIGMHVEVRDSDDKIVLSRVYSSQGRISFTSHTPGEHVICMFSNSTAWFSGAQLRVHLDIQVGEHAIDYAHVAQKEKLTELQLRIRQLLDQVEQITKEQNYQRYREERFRHTSESTNSRVLWWSLAQTVVLVCMGFWQMRHLKSFFEAKKLV 216          
BLAST of Transmembrane emp24 domain-containing protein 10 vs. Ensembl Fly
Match: p24-2 (gene:FBgn0053105 transcript:FBtr0082093)

HSP 1 Score: 85.5001 bits (210), Expect = 6.167e-19
Identity = 56/202 (27.72%), Postives = 97/202 (48.02%), Query Frame = 1
Query:   82 ISL-FILNFLYITSAIRFFVTPNGGKKCLKEEIHKNVLVTGEYDI-----------TDAPGQKASIQVTDSKSHVLYQKDDISKGKFAFTTEEYEMFDVCVETKLMGGGKGPDREVFLDIKHGVETKNYDSLAQAEKLKPLEVELKRLEDLSDEIVKDFQYMRDREEKMRDTNESTHNRVFYFSIFSMGCLMALAVWQVLYL 651
            ISL  IL  L+    + F ++    +KC  EE+     V   Y +             +PG    ++V DS   ++  +   S+G+ +FT+       +C+ +       G    V LDI+ G    +Y  +AQ EKL  L++ +++L D  ++I K+  Y R REE+ R T+EST++RV ++S+     L+ +  W +  L
Sbjct:    6 ISLALILCVLHSACGLYFHIS-QTERKCFIEEVPDETTVIVNYKVELYDPRSNGFMPSSPGIGMHVEVRDSDDKIVLSRVYSSQGRISFTSHTPGEHVICMFSNSTAWFSGAQLRVHLDIQVGEHAIDYAHVAQKEKLTELQLRIRQLLDQVEQITKEQNYQRYREERFRHTSESTNSRVLWWSLAQTVVLVCMGFWHLFNL 206          
BLAST of Transmembrane emp24 domain-containing protein 10 vs. Ensembl Fly
Match: p24-2 (gene:FBgn0053105 transcript:FBtr0303038)

HSP 1 Score: 85.5001 bits (210), Expect = 6.167e-19
Identity = 56/202 (27.72%), Postives = 97/202 (48.02%), Query Frame = 1
Query:   82 ISL-FILNFLYITSAIRFFVTPNGGKKCLKEEIHKNVLVTGEYDI-----------TDAPGQKASIQVTDSKSHVLYQKDDISKGKFAFTTEEYEMFDVCVETKLMGGGKGPDREVFLDIKHGVETKNYDSLAQAEKLKPLEVELKRLEDLSDEIVKDFQYMRDREEKMRDTNESTHNRVFYFSIFSMGCLMALAVWQVLYL 651
            ISL  IL  L+    + F ++    +KC  EE+     V   Y +             +PG    ++V DS   ++  +   S+G+ +FT+       +C+ +       G    V LDI+ G    +Y  +AQ EKL  L++ +++L D  ++I K+  Y R REE+ R T+EST++RV ++S+     L+ +  W +  L
Sbjct:    6 ISLALILCVLHSACGLYFHIS-QTERKCFIEEVPDETTVIVNYKVELYDPRSNGFMPSSPGIGMHVEVRDSDDKIVLSRVYSSQGRISFTSHTPGEHVICMFSNSTAWFSGAQLRVHLDIQVGEHAIDYAHVAQKEKLTELQLRIRQLLDQVEQITKEQNYQRYREERFRHTSESTNSRVLWWSLAQTVVLVCMGFWHLFNL 206          
BLAST of Transmembrane emp24 domain-containing protein 10 vs. Ensembl Fly
Match: CHOp24 (gene:FBgn0029709 transcript:FBtr0343566)

HSP 1 Score: 56.225 bits (134), Expect = 5.092e-9
Identity = 38/178 (21.35%), Postives = 80/178 (44.94%), Query Frame = 1
Query:  154 KKCLKEEIHKNVLVTGEYDITDAPGQKASIQVTDSKSHVLYQKDDISKGKFAFTTEEYEMFDVCVETKLMGGGKGPDREVFLDIKHGVETKNYDSLAQAEKLKPLEVE--LKRLEDLSDEIVKDFQYMRDREEKMRDTNESTHNRVFYFSIFSMGCLMALAVWQVLYLRRYFKSKKLI 681
            ++C  E +         +++ D       I+++   +HV+++ +  S GK+ F       + VC   +         + V   I  G   +        E++   ++E  ++ L      +  + +YM  R++  R  NE+T++RV  +S F    L+ + V QV YL+R+F+ K+++
Sbjct:   34 EECFFENVEGGTKFGVTFEVIDGGFLDVDIKISGPDNHVMHESEKESSGKYTFVAPAKGTYTVCFNNER---SSMTPKLVMFSIDVGDAPQRAPGAPGEEEVGHTKLEDMIRELSGTLTSVKHEQEYMHVRDKIHRSVNENTNSRVVLWSTFEALVLVLMTVGQVYYLKRFFEVKRVV 208          
BLAST of Transmembrane emp24 domain-containing protein 10 vs. Ensembl Zebrafish
Match: tmed10 (transmembrane p24 trafficking protein 10 [Source:ZFIN;Acc:ZDB-GENE-030131-4915])

HSP 1 Score: 262.307 bits (669), Expect = 9.228e-87
Identity = 120/185 (64.86%), Postives = 153/185 (82.70%), Query Frame = 1
Query:  133 FVTPNGGKKCLKEEIHKNVLVTGEYDITDAPGQKASIQVTDSKSHVLYQKDDISKGKFAFTTEEYEMFDVCVETK-LMGGGKGPDREVFLDIKHGVETKNYDSLAQAEKLKPLEVELKRLEDLSDEIVKDFQYMRDREEKMRDTNESTHNRVFYFSIFSMGCLMALAVWQVLYLRRYFKSKKLIE 684
            F  P   +KCL+EEIHK+VLVTGEY+I++ P  K ++++TDS  H+LY K+D +KGKFAFTTE+Y+MF+VC E+K  MG G+ PD+++ LD+KHGVE KNY+ +A+ EKLKPLEVEL+RLEDLS+ IV DF YM+ REE+MRDTNEST+ RV YFSIFSM CL+ LA WQV YLRR+FK+KKLIE
Sbjct:   25 FYLPVRSRKCLREEIHKDVLVTGEYEISEQPNTKTNLKITDSSGHILYVKEDATKGKFAFTTEDYDMFEVCFESKSPMGTGRVPDQQINLDMKHGVEAKNYEEIAKVEKLKPLEVELRRLEDLSESIVNDFAYMKKREEEMRDTNESTNTRVLYFSIFSMCCLIGLATWQVFYLRRFFKAKKLIE 209          
BLAST of Transmembrane emp24 domain-containing protein 10 vs. Ensembl Zebrafish
Match: tmed10 (transmembrane p24 trafficking protein 10 [Source:ZFIN;Acc:ZDB-GENE-030131-4915])

HSP 1 Score: 262.307 bits (669), Expect = 9.228e-87
Identity = 120/185 (64.86%), Postives = 153/185 (82.70%), Query Frame = 1
Query:  133 FVTPNGGKKCLKEEIHKNVLVTGEYDITDAPGQKASIQVTDSKSHVLYQKDDISKGKFAFTTEEYEMFDVCVETK-LMGGGKGPDREVFLDIKHGVETKNYDSLAQAEKLKPLEVELKRLEDLSDEIVKDFQYMRDREEKMRDTNESTHNRVFYFSIFSMGCLMALAVWQVLYLRRYFKSKKLIE 684
            F  P   +KCL+EEIHK+VLVTGEY+I++ P  K ++++TDS  H+LY K+D +KGKFAFTTE+Y+MF+VC E+K  MG G+ PD+++ LD+KHGVE KNY+ +A+ EKLKPLEVEL+RLEDLS+ IV DF YM+ REE+MRDTNEST+ RV YFSIFSM CL+ LA WQV YLRR+FK+KKLIE
Sbjct:   25 FYLPVRSRKCLREEIHKDVLVTGEYEISEQPNTKTNLKITDSSGHILYVKEDATKGKFAFTTEDYDMFEVCFESKSPMGTGRVPDQQINLDMKHGVEAKNYEEIAKVEKLKPLEVELRRLEDLSESIVNDFAYMKKREEEMRDTNESTNTRVLYFSIFSMCCLIGLATWQVFYLRRFFKAKKLIE 209          
BLAST of Transmembrane emp24 domain-containing protein 10 vs. Ensembl Zebrafish
Match: tmed10 (transmembrane p24 trafficking protein 10 [Source:ZFIN;Acc:ZDB-GENE-030131-4915])

HSP 1 Score: 256.529 bits (654), Expect = 1.213e-84
Identity = 118/184 (64.13%), Postives = 151/184 (82.07%), Query Frame = 1
Query:  133 FVTPNGGKKCLKEEIHKNVLVTGEYDITDAPGQKASIQVTDSKSHVLYQKDDISKGKFAFTTEEYEMFDVCVETKLMGGGKGPDREVFLDIKHGVETKNYDSLAQAEKLKPLEVELKRLEDLSDEIVKDFQYMRDREEKMRDTNESTHNRVFYFSIFSMGCLMALAVWQVLYLRRYFKSKKLIE 684
            F  P   +KCL+EEIHK+VLVTGEY+I++ P  K ++++TDS  H+LY K+D +KGKFAFTTE+Y+MF+VC E+K    G+ PD+++ LD+KHGVE KNY+ +A+ EKLKPLEVEL+RLEDLS+ IV DF YM+ REE+MRDTNEST+ RV YFSIFSM CL+ LA WQV YLRR+FK+KKLIE
Sbjct:   25 FYLPVRSRKCLREEIHKDVLVTGEYEISEQPNTKTNLKITDSSGHILYVKEDATKGKFAFTTEDYDMFEVCFESK-SPMGRVPDQQINLDMKHGVEAKNYEEIAKVEKLKPLEVELRRLEDLSESIVNDFAYMKKREEEMRDTNESTNTRVLYFSIFSMCCLIGLATWQVFYLRRFFKAKKLIE 207          
BLAST of Transmembrane emp24 domain-containing protein 10 vs. Ensembl Zebrafish
Match: tmed4 (transmembrane p24 trafficking protein 4 [Source:ZFIN;Acc:ZDB-GENE-040625-140])

HSP 1 Score: 107.457 bits (267), Expect = 5.939e-27
Identity = 66/214 (30.84%), Postives = 111/214 (51.87%), Query Frame = 1
Query:   91 FILNFLYIT-SAIRFFVTPNGGKKCLKEEIHKNVLVTGEYD-----------ITDAPGQKASIQVTDSKSHVLYQKDDISKGKFAFTTEEYEMFDVCVETK-----LMGGGKGPDREVFLDIKHGVETKNYDSLAQAEKLKPLEVELKRLEDLSDEIVKDFQYMRDREEKMRDTNESTHNRVFYFSIFSMGCLMALAVWQVLYLRRYFKSKKLI 681
            F+L F++++ S   +F      KKC  EEI    +V G Y            +   PG    +++ D ++ V+  +   S G+F FT+       +C+ +      L  GGK     V LDI+ G  T NY  +A  +KL  L++ +++L D  ++I K+  Y R REE+ R T+EST+ RV ++SI     L+   +WQ+ +L+ +F++KKL+
Sbjct:   15 FLLLFVWLSPSQALYFHIGETEKKCFIEEIPDETMVIGRYRTQLWDKQAGSFLPSTPGLGMHVEIKDPETKVILSRQYGSDGRFTFTSHTPGEHQICLHSNSTKMALFAGGK---LRVHLDIQVGEHTNNYPEIAAKDKLTELQLRVRQLLDQVEQIQKEQNYQRYREERFRMTSESTNQRVLWWSIAQTVILIITGIWQMKHLKSFFEAKKLV 225          
BLAST of Transmembrane emp24 domain-containing protein 10 vs. Ensembl Zebrafish
Match: tmed9 (transmembrane p24 trafficking protein 9 [Source:ZFIN;Acc:ZDB-GENE-050417-434])

HSP 1 Score: 104.375 bits (259), Expect = 9.763e-26
Identity = 68/222 (30.63%), Postives = 109/222 (49.10%), Query Frame = 1
Query:   64 RMNFYIISLFILNFLYITSAIRFFVTPNGGKKCLKEEIHKNVLVTGEYDITDAPGQKAS-----------IQVTDSKSHVLYQKDDISKGKFAFTTEEYEMFDVCVETK-----LMGGGKGPDREVFLDIKHGVETKNYDSLAQAEKLKPLEVELKRLEDLSDEIVKDFQYMRDREEKMRDTNESTHNRVFYFSIFSMGCLMALAVWQVLYLRRYFKSKKLI 681
            RM F +  L +LN      +  +F      KKC  EEI    ++ G Y       QK             ++V D    V+  +   S+G+F FT+       +C+ +      L  GG      V LDI+ G  T NY  +A  +KL  L++ +++L +  D+I K+  Y R REE+ R T+EST+ RV ++SI     L+A+  WQ+ +L+ +F++KKL+
Sbjct:    5 RMQFTLYFLVLLNIYNSLVSALYFHIGETEKKCFIEEIPDETMIIGNYRTQLYDKQKEEYLPATQGLGMFVEVKDPDEKVILSRQYGSEGRFIFTSHTPGEHQICLHSNSSKFALFAGGM---LRVHLDIQVGEHTNNYAEIAAKDKLTELQLRVRQLMEQVDQIQKEQNYQRYREERFRQTSESTNQRVLWWSIVQTLILVAIGFWQMRHLKSFFEAKKLV 223          
BLAST of Transmembrane emp24 domain-containing protein 10 vs. Ensembl Xenopus
Match: enpp7 (ectonucleotide pyrophosphatase/phosphodiesterase 7 [Source:Xenbase;Acc:XB-GENE-996993])

HSP 1 Score: 260.766 bits (665), Expect = 4.943e-86
Identity = 128/201 (63.68%), Postives = 158/201 (78.61%), Query Frame = 1
Query:   88 LFILNFLYITSAIRFFVTPNGGKKCLKEEIHKNVLVTGEYDITDAPGQ-KASIQVTDSKSHVLYQKDDISKGKFAFTTEEYEMFDVCVETKL-MGGGKGPDREVFLDIKHGVETKNYDSLAQAEKLKPLEVELKRLEDLSDEIVKDFQYMRDREEKMRDTNESTHNRVFYFSIFSMGCLMALAVWQVLYLRRYFKSKKLIE 684
            LF L F      I F + PN  +KCL+EEIHKNVLVTGEY++++A  Q +  +++TDS  H+LY K+D SKGKFAFTTEEY+MF+VC ++KL  G G+ PD+ V L +KHGVE KNY+ +A+ EKLKPLEVEL+RLEDLS+ IV DF YM+ REE+MRDTNEST+ RV YFSIFSM CLM LA WQV YLRR+FK+KKLIE
Sbjct:    8 LFALLFCGYVQPISFSLPPNS-RKCLREEIHKNVLVTGEYELSEAHNQGQVRLKITDSAGHILYSKEDASKGKFAFTTEEYDMFEVCFDSKLPAGAGRVPDQMVNLIMKHGVEAKNYEEIAKVEKLKPLEVELRRLEDLSESIVNDFAYMKKREEEMRDTNESTNVRVLYFSIFSMCCLMGLATWQVFYLRRFFKAKKLIE 207          
BLAST of Transmembrane emp24 domain-containing protein 10 vs. Ensembl Xenopus
Match: enpp7 (ectonucleotide pyrophosphatase/phosphodiesterase 7 [Source:Xenbase;Acc:XB-GENE-996993])

HSP 1 Score: 251.906 bits (642), Expect = 1.521e-82
Identity = 126/206 (61.17%), Postives = 154/206 (74.76%), Query Frame = 1
Query:   88 LFILNFLYITSAIRFFVTPNGGKKCLKEEIHKNVLVTGEYDITDAPGQKASIQ-------VTDSKSHVLYQKDDISKGKFAFTTEEYEMFDVCVETKLMGGGKGPDREVFLDIKHGVETKNYDSLAQAEKLKPLEVELKRLEDLSDEIVKDFQYMRDREEKMRDTNESTHNRVFYFSIFSMGCLMALAVWQVLYLRRYFKSKKLIE 684
            LF L F      I F + PN  +KCL+EEIHKNVLVTGEY++++A  Q   I+       +TDS  H+LY K+D SKGKFAFTTEEY+MF+VC ++     G+ PD+ V L +KHGVE KNY+ +A+ EKLKPLEVEL+RLEDLS+ IV DF YM+ REE+MRDTNEST+ RV YFSIFSM CLM LA WQV YLRR+FK+KKLIE
Sbjct:    8 LFALLFCGYVQPISFSLPPNS-RKCLREEIHKNVLVTGEYELSEAHNQAGFIRSHLSFLNITDSAGHILYSKEDASKGKFAFTTEEYDMFEVCFDS----AGRVPDQMVNLIMKHGVEAKNYEEIAKVEKLKPLEVELRRLEDLSESIVNDFAYMKKREEEMRDTNESTNVRVLYFSIFSMCCLMGLATWQVFYLRRFFKAKKLIE 208          
BLAST of Transmembrane emp24 domain-containing protein 10 vs. Ensembl Xenopus
Match: shroom1 (shroom family member 1 [Source:Xenbase;Acc:XB-GENE-6492080])

HSP 1 Score: 234.958 bits (598), Expect = 4.753e-76
Identity = 116/191 (60.73%), Postives = 146/191 (76.44%), Query Frame = 1
Query:  115 TSAIRFFVTPNGGKKCLKEEIHKNVLVTGEYDITDAPGQKASIQVTDSKSHVLYQKDDISKGKFAFTTEEYEMFDVCVETKLMGGGKG-PDREVFLDIKHGVETKNYDSLAQAEKLKPLEVELKRLEDLSDEIVKDFQYMRDREEKMRDTNESTHNRVFYFSIFSMGCLMALAVWQVLYLRRYFKSKKLIE 684
            T AI F++ P G KKCLKEEIHK+VLVTGEY++++ PG    ++VTDS  H+LY K+D  KGKFAFTT++ ++++VC  +K         D+ + LDIKHGVE KNY  +A+ EKLKPLEVEL+RLEDL+  +VKDF YM+ REE+MRDTNEST  RV YFS FSM CL+ALA WQV YLR +FK+KKLIE
Sbjct:   17 TGAISFYLRPLG-KKCLKEEIHKDVLVTGEYEVSEQPGLTCDLKVTDSIGHILYSKEDARKGKFAFTTDDNDVYEVCFVSKSPSDTLSFTDQLIALDIKHGVEAKNYKDVAETEKLKPLEVELRRLEDLTQSVVKDFSYMKKREEEMRDTNESTSLRVLYFSAFSMFCLVALATWQVFYLRHFFKAKKLIE 206          
BLAST of Transmembrane emp24 domain-containing protein 10 vs. Ensembl Xenopus
Match: tmed4 (transmembrane p24 trafficking protein 4 [Source:NCBI gene;Acc:548496])

HSP 1 Score: 103.219 bits (256), Expect = 3.790e-25
Identity = 61/192 (31.77%), Postives = 99/192 (51.56%), Query Frame = 1
Query:  154 KKCLKEEIHKNVLVTGEYD-----------ITDAPGQKASIQVTDSKSHVLYQKDDISKGKFAFTTEEYEMFDVCVETK-----LMGGGKGPDREVFLDIKHGVETKNYDSLAQAEKLKPLEVELKRLEDLSDEIVKDFQYMRDREEKMRDTNESTHNRVFYFSIFSMGCLMALAVWQVLYLRRYFKSKKLI 681
            K+C  EEI    +V G Y            +   PG    ++V DS   V+  +   S+G+F FT+       +C+ +         GGK     V LDI+ G  T NY  +A  +KL  L++ +++L D  ++I K+  Y R REE+ R T+EST+ RV ++SI     L+   +WQ+ +L+ +F++KKL+
Sbjct:   40 KRCFIEEIPDETMVIGNYKTQLWDKQSETFLPSTPGLGMHVEVKDSDGKVILSRQYGSEGRFTFTSHTPGEHQICLHSNSTRMSFFAGGK---LRVHLDIQIGEHTNNYPEIAAKDKLTELQLRVRQLLDQVEQIQKEQNYQRYREERFRLTSESTNQRVLWWSIAQTLILILTGIWQMRHLKSFFEAKKLV 228          
BLAST of Transmembrane emp24 domain-containing protein 10 vs. Ensembl Xenopus
Match: tmed9 (transmembrane p24 trafficking protein 9 [Source:NCBI gene;Acc:496564])

HSP 1 Score: 95.9005 bits (237), Expect = 2.250e-22
Identity = 59/192 (30.73%), Postives = 97/192 (50.52%), Query Frame = 1
Query:  154 KKCLKEEIHKNVLVTGEYD-----------ITDAPGQKASIQVTDSKSHVLYQKDDISKGKFAFTTEEYEMFDVCVETK-----LMGGGKGPDREVFLDIKHGVETKNYDSLAQAEKLKPLEVELKRLEDLSDEIVKDFQYMRDREEKMRDTNESTHNRVFYFSIFSMGCLMALAVWQVLYLRRYFKSKKLI 681
            KKC  EEI    +V G Y            +   PG    ++V D    V+  +   S+G+F FT+       +C+ +      L  GG      V LDI+ G    +Y  +A  +KL  L++ +++L +  ++I K+  Y R REE+ R T+EST  RV ++SI     L+ + VWQ+ +L+ +F++KKL+
Sbjct:   53 KKCFIEEIPDETMVVGNYRTQMFDKQREDYLPATPGLGMFVEVKDPDDKVILSRQYGSEGRFTFTSHTPGEHQICLHSNSTKFALFAGGM---LRVHLDIQVGEHANDYVDIAAKDKLNTLQLRVRQLIEQVEQIQKEQNYQRWREERFRQTSESTSQRVLWWSIAQTLILVTIGVWQMKHLKGFFEAKKLV 241          
BLAST of Transmembrane emp24 domain-containing protein 10 vs. Ensembl Mouse
Match: Tmed10 (transmembrane p24 trafficking protein 10 [Source:MGI Symbol;Acc:MGI:1915831])

HSP 1 Score: 250.751 bits (639), Expect = 3.634e-82
Identity = 120/188 (63.83%), Postives = 150/188 (79.79%), Query Frame = 1
Query:  133 FVTPNGGKKCLKEEIHKNVLVTGEYDITD----APGQKASIQVTDSKSHVLYQKDDISKGKFAFTTEEYEMFDVCVETKLMGGGKGPDREVFLDIKHGVETKNYDSLAQAEKLKPLEVELKRLEDLSDEIVKDFQYMRDREEKMRDTNESTHNRVFYFSIFSMGCLMALAVWQVLYLRRYFKSKKLIE 684
            F  P   +KCL+EEIHK++LVTG Y+ITD    A G +  +++TDS  H+LY K+D +KGKFAFTTE+Y+MF+VC E+K  G G+ PD+ V LD+KHGVE KNY+ +A+ EKLKPLEVEL+RLEDLS+ IV DF YM+ REE+MRDTNEST+ RV YFSIFSM CL+ LA WQV YLRR+FK+KKLIE
Sbjct:   34 FHLPVNSRKCLREEIHKDLLVTGAYEITDQSGGAGGLRTHLKITDSAGHILYAKEDATKGKFAFTTEDYDMFEVCFESK--GTGRIPDQLVILDMKHGVEAKNYEEIAKVEKLKPLEVELRRLEDLSESIVNDFAYMKKREEEMRDTNESTNTRVLYFSIFSMFCLIGLATWQVFYLRRFFKAKKLIE 219          
BLAST of Transmembrane emp24 domain-containing protein 10 vs. Ensembl Mouse
Match: Tmed10 (transmembrane p24 trafficking protein 10 [Source:MGI Symbol;Acc:MGI:1915831])

HSP 1 Score: 173.326 bits (438), Expect = 2.004e-53
Identity = 82/118 (69.49%), Postives = 98/118 (83.05%), Query Frame = 1
Query:  331 MFDVCVETKLMGGGKGPDREVFLDIKHGVETKNYDSLAQAEKLKPLEVELKRLEDLSDEIVKDFQYMRDREEKMRDTNESTHNRVFYFSIFSMGCLMALAVWQVLYLRRYFKSKKLIE 684
            MF+VC E+K  G G+ PD+ V LD+KHGVE KNY+ +A+ EKLKPLEVEL+RLEDLS+ IV DF YM+ REE+MRDTNEST+ RV YFSIFSM CL+ LA WQV YLRR+FK+KKLIE
Sbjct:    1 MFEVCFESK--GTGRIPDQLVILDMKHGVEAKNYEEIAKVEKLKPLEVELRRLEDLSESIVNDFAYMKKREEEMRDTNESTNTRVLYFSIFSMFCLIGLATWQVFYLRRFFKAKKLIE 116          
BLAST of Transmembrane emp24 domain-containing protein 10 vs. Ensembl Mouse
Match: Tmed9 (transmembrane p24 trafficking protein 9 [Source:MGI Symbol;Acc:MGI:1914761])

HSP 1 Score: 100.138 bits (248), Expect = 5.159e-24
Identity = 60/192 (31.25%), Postives = 99/192 (51.56%), Query Frame = 1
Query:  154 KKCLKEEIHKNVLVTGEYDI-----------TDAPGQKASIQVTDSKSHVLYQKDDISKGKFAFTTEEYEMFDVCVETK-----LMGGGKGPDREVFLDIKHGVETKNYDSLAQAEKLKPLEVELKRLEDLSDEIVKDFQYMRDREEKMRDTNESTHNRVFYFSIFSMGCLMALAVWQVLYLRRYFKSKKLI 681
            KKC  EEI    +V G Y                PG    ++V D +  V+  +   S+G+F FT+       +C+ +      L  GG      V LDI+ G    +Y  +A  +KL  L++ +++L +  ++I K+  Y R REE+ R T+EST+ RV ++SI     L+A+ VWQ+ +L+ +F++KKL+
Sbjct:   47 KKCFIEEIPDETMVIGNYRTQLYDKQREEYQPATPGLGMFVEVKDPEDKVILARQYGSEGRFTFTSHTPGEHQICLHSNSTKFSLFAGGM---LRVHLDIQVGEHANDYAEIAAKDKLSELQLRVRQLVEQVEQIQKEQNYQRWREERFRQTSESTNQRVLWWSILQTLILVAIGVWQMRHLKSFFEAKKLV 235          
BLAST of Transmembrane emp24 domain-containing protein 10 vs. Ensembl Mouse
Match: Tmed4 (transmembrane p24 trafficking protein 4 [Source:MGI Symbol;Acc:MGI:1915070])

HSP 1 Score: 99.7525 bits (247), Expect = 5.696e-24
Identity = 63/215 (29.30%), Postives = 103/215 (47.91%), Query Frame = 1
Query:   85 SLFILNFLYITSAIRFFVTPNGGKKCLKEEIHKNVLVTGEYD-----------ITDAPGQKASIQVTDSKSHVLYQKDDISKGKFAFTTEEYEMFDVCVETK-----LMGGGKGPDREVFLDIKHGVETKNYDSLAQAEKLKPLEVELKRLEDLSDEIVKDFQYMRDREEKMRDTNESTHNRVFYFSIFSMGCLMALAVWQVLYLRRYFKSKKLI 681
             L +L      +   +F      K+C  EEI    +V G Y            +   PG    ++V D    V+  +   S+G+F FT+       +C+ +      L  GGK     V LDI+ G    NY  +A  +KL  L++  ++L D  ++I K+  Y R REE+ R T+EST+ RV ++SI     L+   +WQ+ +L+ +F++KKL+
Sbjct:   16 GLLVLTVCAACARGLYFHIGETEKRCFIEEIPDETMVIGNYRTQMWDKQKEVFLPSTPGLGMHVEVKDPDGKVVLSRQYGSEGRFTFTSHTPGDHQICLHSNSTRMALFAGGK---LRVHLDIQVGEHANNYPEIAAKDKLTELQLRARQLLDQVEQIQKEQDYQRYREERFRLTSESTNQRVLWWSIAQTVILILTGIWQMRHLKSFFEAKKLV 227          
BLAST of Transmembrane emp24 domain-containing protein 10 vs. Ensembl Mouse
Match: Tmed9 (transmembrane p24 trafficking protein 9 [Source:MGI Symbol;Acc:MGI:1914761])

HSP 1 Score: 92.0485 bits (227), Expect = 2.251e-21
Identity = 51/158 (32.28%), Postives = 89/158 (56.33%), Query Frame = 1
Query:  223 PGQKASIQVTDSKSHVLYQKDDISKGKFAFTTEEYEMFDVCVETK-----LMGGGKGPDREVFLDIKHGVETKNYDSLAQAEKLKPLEVELKRLEDLSDEIVKDFQYMRDREEKMRDTNESTHNRVFYFSIFSMGCLMALAVWQVLYLRRYFKSKKLI 681
            PG    ++V D +  V+  +   S+G+F FT+       +C+ +      L  GG      V LDI+ G    +Y  +A  +KL  L++ +++L +  ++I K+  Y R REE+ R T+EST+ RV ++SI     L+A+ VWQ+ +L+ +F++KKL+
Sbjct:   55 PGLGMFVEVKDPEDKVILARQYGSEGRFTFTSHTPGEHQICLHSNSTKFSLFAGGM---LRVHLDIQVGEHANDYAEIAAKDKLSELQLRVRQLVEQVEQIQKEQNYQRWREERFRQTSESTNQRVLWWSILQTLILVAIGVWQMRHLKSFFEAKKLV 209          
BLAST of Transmembrane emp24 domain-containing protein 10 vs. UniProt/SwissProt
Match: sp|Q28735|TMEDA_RABIT (Transmembrane emp24 domain-containing protein 10 OS=Oryctolagus cuniculus OX=9986 GN=TMED10 PE=1 SV=1)

HSP 1 Score: 252.292 bits (643), Expect = 8.127e-82
Identity = 123/192 (64.06%), Postives = 153/192 (79.69%), Query Frame = 1
Query:  121 AIRFFVTPNGGKKCLKEEIHKNVLVTGEYDITD----APGQKASIQVTDSKSHVLYQKDDISKGKFAFTTEEYEMFDVCVETKLMGGGKGPDREVFLDIKHGVETKNYDSLAQAEKLKPLEVELKRLEDLSDEIVKDFQYMRDREEKMRDTNESTHNRVFYFSIFSMGCLMALAVWQVLYLRRYFKSKKLIE 684
            AI F + P   +KCL+EEIHK++LVTG Y+ITD    A G +  +++TDS  H+LY K+D SKGKFAFTTE+Y+MF+VC E+K  G G+ PD+ V LD+KHGVE KNY+ +A+ EKLKPLEVEL+RLEDLS+ IV DF YM+ REE+MRDTNEST+ RV YFSIFSM CL+ LA WQV YLRR+FK+KKLIE
Sbjct:   31 AISFHL-PVNSRKCLREEIHKDLLVTGAYEITDQSGGAGGLRTHLKITDSAGHILYSKEDASKGKFAFTTEDYDMFEVCFESK--GTGRIPDQLVILDMKHGVEAKNYEEIAKVEKLKPLEVELRRLEDLSESIVNDFAYMKKREEEMRDTNESTNTRVLYFSIFSMFCLIGLATWQVFYLRRFFKAKKLIE 219          
BLAST of Transmembrane emp24 domain-containing protein 10 vs. UniProt/SwissProt
Match: sp|Q5E971|TMEDA_BOVIN (Transmembrane emp24 domain-containing protein 10 OS=Bos taurus OX=9913 GN=TMED10 PE=2 SV=1)

HSP 1 Score: 251.136 bits (640), Expect = 2.305e-81
Identity = 122/192 (63.54%), Postives = 153/192 (79.69%), Query Frame = 1
Query:  121 AIRFFVTPNGGKKCLKEEIHKNVLVTGEYDITD----APGQKASIQVTDSKSHVLYQKDDISKGKFAFTTEEYEMFDVCVETKLMGGGKGPDREVFLDIKHGVETKNYDSLAQAEKLKPLEVELKRLEDLSDEIVKDFQYMRDREEKMRDTNESTHNRVFYFSIFSMGCLMALAVWQVLYLRRYFKSKKLIE 684
            AI F + P   +KCL+EEIHK++LVTG Y+ITD    A G +  +++TDS  H+LY K+D +KGKFAFTTE+Y+MF+VC E+K  G G+ PD+ V LD+KHGVE KNY+ +A+ EKLKPLEVEL+RLEDLS+ IV DF YM+ REE+MRDTNEST+ RV YFSIFSM CL+ LA WQV YLRR+FK+KKLIE
Sbjct:   31 AISFHL-PVNSRKCLREEIHKDLLVTGAYEITDQSGGAGGLRTHLKITDSAGHILYSKEDATKGKFAFTTEDYDMFEVCFESK--GTGRIPDQLVILDMKHGVEAKNYEEIAKVEKLKPLEVELRRLEDLSESIVNDFAYMKKREEEMRDTNESTNTRVLYFSIFSMFCLIGLATWQVFYLRRFFKAKKLIE 219          
BLAST of Transmembrane emp24 domain-containing protein 10 vs. UniProt/SwissProt
Match: sp|P49755|TMEDA_HUMAN (Transmembrane emp24 domain-containing protein 10 OS=Homo sapiens OX=9606 GN=TMED10 PE=1 SV=2)

HSP 1 Score: 250.751 bits (639), Expect = 2.460e-81
Identity = 121/192 (63.02%), Postives = 154/192 (80.21%), Query Frame = 1
Query:  121 AIRFFVTPNGGKKCLKEEIHKNVLVTGEYDITD----APGQKASIQVTDSKSHVLYQKDDISKGKFAFTTEEYEMFDVCVETKLMGGGKGPDREVFLDIKHGVETKNYDSLAQAEKLKPLEVELKRLEDLSDEIVKDFQYMRDREEKMRDTNESTHNRVFYFSIFSMGCLMALAVWQVLYLRRYFKSKKLIE 684
            AI F + P   +KCL+EEIHK++LVTG Y+I+D    A G ++ +++TDS  H+LY K+D +KGKFAFTTE+Y+MF+VC E+K  G G+ PD+ V LD+KHGVE KNY+ +A+ EKLKPLEVEL+RLEDLS+ IV DF YM+ REE+MRDTNEST+ RV YFSIFSM CL+ LA WQV YLRR+FK+KKLIE
Sbjct:   31 AISFHL-PINSRKCLREEIHKDLLVTGAYEISDQSGGAGGLRSHLKITDSAGHILYSKEDATKGKFAFTTEDYDMFEVCFESK--GTGRIPDQLVILDMKHGVEAKNYEEIAKVEKLKPLEVELRRLEDLSESIVNDFAYMKKREEEMRDTNESTNTRVLYFSIFSMFCLIGLATWQVFYLRRFFKAKKLIE 219          
BLAST of Transmembrane emp24 domain-containing protein 10 vs. UniProt/SwissProt
Match: sp|Q9D1D4|TMEDA_MOUSE (Transmembrane emp24 domain-containing protein 10 OS=Mus musculus OX=10090 GN=Tmed10 PE=1 SV=1)

HSP 1 Score: 250.751 bits (639), Expect = 2.542e-81
Identity = 120/188 (63.83%), Postives = 150/188 (79.79%), Query Frame = 1
Query:  133 FVTPNGGKKCLKEEIHKNVLVTGEYDITD----APGQKASIQVTDSKSHVLYQKDDISKGKFAFTTEEYEMFDVCVETKLMGGGKGPDREVFLDIKHGVETKNYDSLAQAEKLKPLEVELKRLEDLSDEIVKDFQYMRDREEKMRDTNESTHNRVFYFSIFSMGCLMALAVWQVLYLRRYFKSKKLIE 684
            F  P   +KCL+EEIHK++LVTG Y+ITD    A G +  +++TDS  H+LY K+D +KGKFAFTTE+Y+MF+VC E+K  G G+ PD+ V LD+KHGVE KNY+ +A+ EKLKPLEVEL+RLEDLS+ IV DF YM+ REE+MRDTNEST+ RV YFSIFSM CL+ LA WQV YLRR+FK+KKLIE
Sbjct:   34 FHLPVNSRKCLREEIHKDLLVTGAYEITDQSGGAGGLRTHLKITDSAGHILYAKEDATKGKFAFTTEDYDMFEVCFESK--GTGRIPDQLVILDMKHGVEAKNYEEIAKVEKLKPLEVELRRLEDLSESIVNDFAYMKKREEEMRDTNESTNTRVLYFSIFSMFCLIGLATWQVFYLRRFFKAKKLIE 219          
BLAST of Transmembrane emp24 domain-containing protein 10 vs. UniProt/SwissProt
Match: sp|O35587|TMEDA_MESAU (Transmembrane protein Tmp21 OS=Mesocricetus auratus OX=10036 GN=TMED10 PE=1 SV=1)

HSP 1 Score: 250.751 bits (639), Expect = 2.927e-81
Identity = 122/192 (63.54%), Postives = 153/192 (79.69%), Query Frame = 1
Query:  121 AIRFFVTPNGGKKCLKEEIHKNVLVTGEYDITD----APGQKASIQVTDSKSHVLYQKDDISKGKFAFTTEEYEMFDVCVETKLMGGGKGPDREVFLDIKHGVETKNYDSLAQAEKLKPLEVELKRLEDLSDEIVKDFQYMRDREEKMRDTNESTHNRVFYFSIFSMGCLMALAVWQVLYLRRYFKSKKLIE 684
            AI F + P   +KCL+EEIHK++LVTG Y+ITD    A G +  +++TDS  H+LY K+D +KGKFAFTTE+Y+MF+VC E+K  G G+ PD+ V LD+KHGVE KNY+ +A+ EKLKPLEVEL+RLEDLS+ IV DF YM+ REE+MRDTNEST+ RV YFSIFSM CL+ LA WQV YLRR+FK+KKLIE
Sbjct:   31 AISFHL-PVNSRKCLREEIHKDLLVTGAYEITDQSGGAGGLRTHLKITDSAGHILYAKEDATKGKFAFTTEDYDMFEVCFESK--GTGRIPDQLVILDMKHGVEAKNYEEIAKVEKLKPLEVELRRLEDLSESIVNDFAYMKKREEEMRDTNESTNTRVLYFSIFSMLCLIGLATWQVFYLRRFFKAKKLIE 219          
BLAST of Transmembrane emp24 domain-containing protein 10 vs. TrEMBL
Match: A0A210QCL1 (Transmembrane emp24 domain-containing protein 10 OS=Mizuhopecten yessoensis OX=6573 GN=KP79_PYT09705 PE=3 SV=1)

HSP 1 Score: 290.812 bits (743), Expect = 1.035e-94
Identity = 136/206 (66.02%), Postives = 168/206 (81.55%), Query Frame = 1
Query:   67 MNFYIISLFILNFLYITSAIRFFVTPNGGKKCLKEEIHKNVLVTGEYDITDAPGQKASIQVTDSKSHVLYQKDDISKGKFAFTTEEYEMFDVCVETKLMGGGKGPDREVFLDIKHGVETKNYDSLAQAEKLKPLEVELKRLEDLSDEIVKDFQYMRDREEKMRDTNESTHNRVFYFSIFSMGCLMALAVWQVLYLRRYFKSKKLIE 684
            M+   ++  I    + +     F  P   KKCL+EEIHK+VLVTG+Y+++DAPGQKA++ VTDSK H+LY KDD  KGKFAFTTEEY+MF+VC +TK++GGG G DREV LD+KHG+E K+YD LA+AEKLKPLEVEL+RLEDLS  IV DF+YM++RE++MRDTNESTH+RV YFSIFSM CL+ LA WQVLYLRRYFK+KKLIE
Sbjct:    1 MDLTQLACVIFFLCFNSFDCLMFHLPVNSKKCLREEIHKDVLVTGDYELSDAPGQKATLAVTDSKGHILYTKDDAKKGKFAFTTEEYDMFEVCFQTKMVGGGHGGDREVTLDMKHGIEAKSYDDLAKAEKLKPLEVELRRLEDLSKSIVDDFEYMKEREKEMRDTNESTHSRVMYFSIFSMCCLLGLATWQVLYLRRYFKAKKLIE 206          
BLAST of Transmembrane emp24 domain-containing protein 10 vs. TrEMBL
Match: A0A1S3II12 (transmembrane emp24 domain-containing protein 10 OS=Lingula unguis OX=7574 GN=LOC106164225 PE=3 SV=1)

HSP 1 Score: 287.73 bits (735), Expect = 1.527e-93
Identity = 138/206 (66.99%), Postives = 163/206 (79.13%), Query Frame = 1
Query:   67 MNFYIISLFILNFLYITSAIRFFVTPNGGKKCLKEEIHKNVLVTGEYDITDAPGQKASIQVTDSKSHVLYQKDDISKGKFAFTTEEYEMFDVCVETKLMGGGKGPDREVFLDIKHGVETKNYDSLAQAEKLKPLEVELKRLEDLSDEIVKDFQYMRDREEKMRDTNESTHNRVFYFSIFSMGCLMALAVWQVLYLRRYFKSKKLIE 684
            M F+   L I +   ++     F  P   KKCLKEEIHKNVLVTG YD+T+APGQ+  + V DS+ H+LYQKDD SKGKFAFTTE+Y+MF+VC ETKL  G   PDREV +D+K GVE KNY++LA+AEKLKPLEVEL++LEDLS+ IV DF YMR REE+MRDTNESTH+RV YFSIFSM CL+ LA WQVLYLRRYFK+KKLIE
Sbjct:    1 MEFWQYLLLISSIFLVSIDALSFHLPINQKKCLKEEIHKNVLVTGIYDLTEAPGQRTKLVVVDSRGHILYQKDDASKGKFAFTTEDYDMFEVCFETKLPMGTHAPDREVTIDVKTGVEAKNYEALAKAEKLKPLEVELRKLEDLSEAIVNDFAYMRAREEEMRDTNESTHSRVLYFSIFSMCCLLGLASWQVLYLRRYFKAKKLIE 206          
BLAST of Transmembrane emp24 domain-containing protein 10 vs. TrEMBL
Match: V4AC86 (GOLD domain-containing protein OS=Lottia gigantea OX=225164 GN=LOTGIDRAFT_172557 PE=3 SV=1)

HSP 1 Score: 282.337 bits (721), Expect = 2.009e-91
Identity = 134/204 (65.69%), Postives = 165/204 (80.88%), Query Frame = 1
Query:   73 FYIISLFILNFLYITSAIRFFVTPNGGKKCLKEEIHKNVLVTGEYDITDAPGQKASIQVTDSKSHVLYQKDDISKGKFAFTTEEYEMFDVCVETKLMGGGKGPDREVFLDIKHGVETKNYDSLAQAEKLKPLEVELKRLEDLSDEIVKDFQYMRDREEKMRDTNESTHNRVFYFSIFSMGCLMALAVWQVLYLRRYFKSKKLIE 684
            F +  LF+   +   +AI F ++PN  KKCL++EIHK+VLVTGEY+++DAPGQK  + VTDSK H+LY K+  SKGKFAFTTEEY+MF++C ETK+ GGG G DRE+ L +KHGVE K+Y+ +A+A+KLKPLEVEL++LED+S  IV DF YMR REE+MRDTNESTH RV YFSIFSM CL  LA WQVLYLRRYFK+KKLIE
Sbjct:    4 FQVFVLFMTLCITNLNAIMFHLSPNQ-KKCLRDEIHKDVLVTGEYELSDAPGQKTHLTVTDSKEHILYSKEGASKGKFAFTTEEYDMFEICFETKMPGGGHGVDREISLILKHGVEAKSYEDIAKADKLKPLEVELRKLEDMSQSIVDDFAYMRAREEEMRDTNESTHTRVMYFSIFSMCCLFGLATWQVLYLRRYFKAKKLIE 206          
BLAST of Transmembrane emp24 domain-containing protein 10 vs. TrEMBL
Match: K1QBY6 (Transmembrane protein Tmp21 OS=Crassostrea gigas OX=29159 GN=CGI_10015076 PE=3 SV=1)

HSP 1 Score: 280.411 bits (716), Expect = 5.414e-91
Identity = 130/177 (73.45%), Postives = 151/177 (85.31%), Query Frame = 1
Query:  154 KKCLKEEIHKNVLVTGEYDITDAPGQKASIQVTDSKSHVLYQKDDISKGKFAFTTEEYEMFDVCVETKLMGGGKGPDREVFLDIKHGVETKNYDSLAQAEKLKPLEVELKRLEDLSDEIVKDFQYMRDREEKMRDTNESTHNRVFYFSIFSMGCLMALAVWQVLYLRRYFKSKKLIE 684
            KKCLKEEIHK+VLVTGEY ++D PG K  + VTDSK H+LYQKDD  KGKFAFTTEEY+MF+VC   ++ GGG+ PDREV LD+KHGVE K+YD LA+AEKLKPLEVEL+RLEDLS  IV DF+YM+ RE+ MRDTNESTH+RV YFSIFSM CL+ LA WQVLYLRR+FK+KKLIE
Sbjct:    9 KKCLKEEIHKDVLVTGEYQLSDVPGHKTQLLVTDSKGHILYQKDDAKKGKFAFTTEEYDMFEVCFNNRMPGGGQSPDREVSLDMKHGVEAKSYDELAKAEKLKPLEVELRRLEDLSKSIVDDFEYMKSREKMMRDTNESTHSRVMYFSIFSMCCLLGLATWQVLYLRRFFKAKKLIE 185          
BLAST of Transmembrane emp24 domain-containing protein 10 vs. TrEMBL
Match: T1EJC8 (GOLD domain-containing protein OS=Helobdella robusta OX=6412 GN=20196678 PE=3 SV=1)

HSP 1 Score: 276.559 bits (706), Expect = 3.829e-89
Identity = 134/199 (67.34%), Postives = 161/199 (80.90%), Query Frame = 1
Query:   88 LFILNFLYITSAIRFFVTPNGGKKCLKEEIHKNVLVTGEYDITDAPGQKASIQVTDSKSHVLYQKDDISKGKFAFTTEEYEMFDVCVETKLMGGGKGPDREVFLDIKHGVETKNYDSLAQAEKLKPLEVELKRLEDLSDEIVKDFQYMRDREEKMRDTNESTHNRVFYFSIFSMGCLMALAVWQVLYLRRYFKSKKLIE 684
            LF+L+FL   S+I+F + P G KKCLKEEIHK+VLVTGEY IT  P QKAS++V DSK H LY K+D  KGKFAFTTEE++MF++C E+ +  G  G DREV L +K GVE KNY  +A+AEKLKP+E+ELK+LEDLS+ IV DF  M+DREE+MRDTNESTH+RV YFS+FSM CL+ LA WQVLYLRRYFKSKKLIE
Sbjct:    3 LFLLHFLSEISSIQFNL-PAGQKKCLKEEIHKDVLVTGEYSITAVPEQKASLKVVDSKGHFLYNKEDAEKGKFAFTTEEFDMFEICFESHVPHGVHGLDREVSLTVKRGVEAKNYADIAKAEKLKPMELELKKLEDLSEAIVSDFARMKDREEEMRDTNESTHSRVLYFSLFSMSCLLGLATWQVLYLRRYFKSKKLIE 200          
BLAST of Transmembrane emp24 domain-containing protein 10 vs. Ensembl Cavefish
Match: tmed10 (transmembrane p24 trafficking protein 10 [Source:NCBI gene;Acc:103042340])

HSP 1 Score: 262.307 bits (669), Expect = 5.625e-87
Identity = 123/189 (65.08%), Postives = 156/189 (82.54%), Query Frame = 1
Query:  121 AIRFFVTPNGGKKCLKEEIHKNVLVTGEYDITDAPGQKASIQVTDSKSHVLYQKDDISKGKFAFTTEEYEMFDVCVETK-LMGGGKGPDREVFLDIKHGVETKNYDSLAQAEKLKPLEVELKRLEDLSDEIVKDFQYMRDREEKMRDTNESTHNRVFYFSIFSMGCLMALAVWQVLYLRRYFKSKKLIE 684
            +I FF+ P   +KCLKEEIHK+VLVTGEY+I++ P  K ++++TDS  H+LY K+D +KGKFAFTTE+Y+MF+VC E+K  MG G+ PD+ + LD+KHGVE KNY+ +A+ EKLKPLEVEL+RLEDLS+ IV DF YM+ REE+MRDTNEST+ RV YFSIFSM CL+ LA WQV YLRR+FK+KKLIE
Sbjct:   19 SISFFL-PVRTRKCLKEEIHKDVLVTGEYEISEQPNTKTNLKITDSSGHILYSKEDATKGKFAFTTEDYDMFEVCFESKSQMGTGRVPDQLINLDMKHGVEAKNYEEIAKVEKLKPLEVELRRLEDLSESIVNDFAYMKKREEEMRDTNESTNTRVLYFSIFSMCCLIGLATWQVFYLRRFFKAKKLIE 206          
BLAST of Transmembrane emp24 domain-containing protein 10 vs. Ensembl Cavefish
Match: tmed9 (transmembrane p24 trafficking protein 9 [Source:NCBI gene;Acc:103030438])

HSP 1 Score: 113.235 bits (282), Expect = 4.215e-29
Identity = 69/222 (31.08%), Postives = 113/222 (50.90%), Query Frame = 1
Query:   64 RMNFYIISLFILNFLYITSAIRFFVTPNGGKKCLKEEIHKNVLVTGEYDITDAPGQKAS-----------IQVTDSKSHVLYQKDDISKGKFAFTTEEYEMFDVCVETK-----LMGGGKGPDREVFLDIKHGVETKNYDSLAQAEKLKPLEVELKRLEDLSDEIVKDFQYMRDREEKMRDTNESTHNRVFYFSIFSMGCLMALAVWQVLYLRRYFKSKKLI 681
            RM F + ++ +LNF Y   +  +F      KKC  EEI    ++ G Y       QK             ++V D    V+  +   S+G+F FT+       +C+ +      L  GG      V LDI+ G  T NY+ +A  +KL  L++ +++L +  D+I K+  Y R REE+ R T+EST+ RV ++SI     L+A+  WQ+ +L+ +F++KKL+
Sbjct:    5 RMQFTLCTVLVLNFCYSLVSALYFHIGETEKKCFIEEIPDETMIIGNYRTQLYDKQKEEYLPATQGLGMFVEVKDPDEKVILSRQYGSEGRFTFTSHTPGEHQICLHSNSSKFSLFAGGM---LRVHLDIQVGEHTNNYEVIAAKDKLTELQLRVRQLVEQVDQIQKEQNYQRYREERFRQTSESTNQRVLWWSIVQTLILVAIGFWQMRHLKSFFEAKKLV 223          
BLAST of Transmembrane emp24 domain-containing protein 10 vs. Ensembl Cavefish
Match: tmed9 (transmembrane p24 trafficking protein 9 [Source:NCBI gene;Acc:103030438])

HSP 1 Score: 110.923 bits (276), Expect = 3.081e-28
Identity = 68/221 (30.77%), Postives = 112/221 (50.68%), Query Frame = 1
Query:   67 MNFYIISLFILNFLYITSAIRFFVTPNGGKKCLKEEIHKNVLVTGEYDITDAPGQKAS-----------IQVTDSKSHVLYQKDDISKGKFAFTTEEYEMFDVCVETK-----LMGGGKGPDREVFLDIKHGVETKNYDSLAQAEKLKPLEVELKRLEDLSDEIVKDFQYMRDREEKMRDTNESTHNRVFYFSIFSMGCLMALAVWQVLYLRRYFKSKKLI 681
            M F + ++ +LNF Y   +  +F      KKC  EEI    ++ G Y       QK             ++V D    V+  +   S+G+F FT+       +C+ +      L  GG      V LDI+ G  T NY+ +A  +KL  L++ +++L +  D+I K+  Y R REE+ R T+EST+ RV ++SI     L+A+  WQ+ +L+ +F++KKL+
Sbjct:   15 MQFTLCTVLVLNFCYSLVSALYFHIGETEKKCFIEEIPDETMIIGNYRTQLYDKQKEEYLPATQGLGMFVEVKDPDEKVILSRQYGSEGRFTFTSHTPGEHQICLHSNSSKFSLFAGGM---LRVHLDIQVGEHTNNYEVIAAKDKLTELQLRVRQLVEQVDQIQKEQNYQRYREERFRQTSESTNQRVLWWSIVQTLILVAIGFWQMRHLKSFFEAKKLV 232          
BLAST of Transmembrane emp24 domain-containing protein 10 vs. Ensembl Cavefish
Match: tmed4 (transmembrane p24 trafficking protein 4 [Source:ZFIN;Acc:ZDB-GENE-040625-140])

HSP 1 Score: 105.916 bits (263), Expect = 1.855e-26
Identity = 66/214 (30.84%), Postives = 108/214 (50.47%), Query Frame = 1
Query:   88 LFILNFLYITSAIRFFVTPNGGKKCLKEEIHKNVLVTGEYD-----------ITDAPGQKASIQVTDSKSHVLYQKDDISKGKFAFTTEEYEMFDVCVETK-----LMGGGKGPDREVFLDIKHGVETKNYDSLAQAEKLKPLEVELKRLEDLSDEIVKDFQYMRDREEKMRDTNESTHNRVFYFSIFSMGCLMALAVWQVLYLRRYFKSKKLI 681
            L +L   +  S   +F      KKC  EEI    +V G+Y            +   PG    +++ D  + V+  +   S G+F FT+       +C+ +      L  GGK     V LDI+ G  T NY  +A  +KL  L++ +++L D  ++I K+  Y R REE+ R T+EST+ RV ++SI     L+  A+WQ+ +L+ +F++KKL+
Sbjct:   16 LLLLFAWFSPSRALYFHIGETEKKCFIEEIPDETMVIGKYRTQLWDKQTGSFLPATPGLGMHVEIKDPDTKVILSRQYGSDGRFTFTSHTPGEHQICLHSNSTKMALFAGGK---LRVHLDIQVGEHTNNYPEIAAKDKLTELQLRVRQLLDQVEQIQKEQNYQRYREERFRMTSESTNQRVLWWSIAQTIILITAAIWQMRHLKSFFEAKKLV 226          
BLAST of Transmembrane emp24 domain-containing protein 10 vs. Ensembl Cavefish
Match: si:ch211-255i20.3 (transmembrane emp24 domain-containing protein 11-like [Source:NCBI gene;Acc:103034721])

HSP 1 Score: 78.1814 bits (191), Expect = 2.524e-16
Identity = 56/221 (25.34%), Postives = 105/221 (47.51%), Query Frame = 1
Query:   70 NFYIISLFILNFLYITSAI-------RFFVTPNGGKKCLKEEIHKNVLVTGEYDIT--------DAPGQKASIQVTDSKSHVLYQKDDISKGKFAFTTEEYEMFDVCVETK--LMGGGKGPDREVFLDIKHGVETKNYDSLAQAEKLKPLEVELKRLEDLSDEIVKDFQYMRDREEKMRDTNESTHNRVFYFSIFSMGCLMALAVWQVLYLRRYFKSKKLI 681
            +++ I+   L++ Y+ +A         +F   +  +KC+ EEI ++VLVTG + +         ++P    ++ V D  + VL  K     GKF FT+       +CV++         G   +V LD++ G  T +  +    E  K +E  ++ L D    I K   + R+REE  R+ +E+T+  V ++++     L+ +  WQ+  L+ +   KKL+
Sbjct:   12 HYFGITTMKLSWCYLLAACFVSLSFAMYFDLVDQREKCIIEEIPEDVLVTGYFFVEHWDEKKQDNSPHLGVTVTVRDPNNEVLLMKRFGRYGKFTFTSHASGQHFLCVKSNSTRFSAFAGERLKVHLDVQMGEHTIDPSAEKAKETFKTMEYRMQHLIDQMQYISKQQDFQREREELFREMSETTNGSVLWWALIQTSILLTVGFWQMRNLKNFLIEKKLV 232          
BLAST of Transmembrane emp24 domain-containing protein 10 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000001929.1 (pep scaffold:Pmarinus_7.0:GL476868:73855:89088:-1 gene:ENSPMAG00000001745.1 transcript:ENSPMAT00000001929.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 93.9745 bits (232), Expect = 2.996e-23
Identity = 51/162 (31.48%), Postives = 88/162 (54.32%), Query Frame = 1
Query:  211 ITDAPGQKASIQVTDSKSHVLYQKDDISKGKFAFTTEEYEMFDVCVETK-----LMGGGKGPDREVFLDIKHGVETKNYDSLAQAEKLKPLEVELKRLEDLSDEIVKDFQYMRDREEKMRDTNESTHNRVFYFSIFSMGCLMALAVWQVLYLRRYFKSKKLI 681
            +   PG    ++V D    V+  K   S+G+F FT+       +C+ +      L  GG+     V LDI+ G    +Y  +A  +KL  L++ +++L D  ++I K+  Y R REE+ R T+EST+ RV ++SI     L+   +WQ+ +L+ +F++KKL+
Sbjct:   18 LPSTPGLGMHVEVKDPDGKVILSKQYSSEGRFTFTSHTPGEHQICLHSNSTKIALFAGGR---LRVHLDIQVGEHANDYSEIAAKDKLTELQLRVRQLLDQVEQIQKEQNYQRYREERFRQTSESTNQRVLWWSIAQTLILITTGIWQMRHLKSFFEAKKLV 176          
BLAST of Transmembrane emp24 domain-containing protein 10 vs. Ensembl Sea Lamprey
Match: tmed2 (transmembrane p24 trafficking protein 2 [Source:ZFIN;Acc:ZDB-GENE-030131-269])

HSP 1 Score: 56.225 bits (134), Expect = 4.351e-10
Identity = 37/147 (25.17%), Postives = 69/147 (46.94%), Query Frame = 1
Query:  241 IQVTDSKSHVLYQKDDISKGKFAFTTEEYEMFDVCVETKLMGGGKGPDREVFLDIKHGVETKNYDSLAQAEKLKPLEVELKRLEDLSDEIVKDFQYMRDREEKMRDTNESTHNRVFYFSIFSMGCLMALAVWQVLYLRRYFKSKKLI 681
            +Q+T      +Y+ D  S GK+ F      ++  C   K+        + V   I  G   K  D   +A + K LE  +  L      +  + +YM  RE   R  N++T++RV  ++ F    L+A+ + Q+ YL+R+F+ ++++
Sbjct:    1 VQITGPDGREIYRGDRESNGKYTFAAHMDGVYKFCFGNKM---STMTPKMVMFTIDMGETPKGQDMETEAHQNK-LEEMINELATAMTAVKHEQEYMEVRERIHRSVNDNTNSRVVLWAFFEALVLVAMTLGQIYYLKRFFEVRRVV 143          
BLAST of Transmembrane emp24 domain-containing protein 10 vs. Ensembl Sea Lamprey
Match: tmed3 (transmembrane p24 trafficking protein 3 [Source:ZFIN;Acc:ZDB-GENE-030131-8335])

HSP 1 Score: 45.0542 bits (105), Expect = 9.639e-6
Identity = 42/183 (22.95%), Postives = 81/183 (44.26%), Query Frame = 1
Query:  133 FVTPNGGKKCLKEEIHKNVLVTGEYDITDAPGQKASIQVTDSKSHVLYQKDDISKGKFAFTTEEYEMFDVCVETKLMGGGKGPDREVFLDIKHGVETKNY-DSLAQAEKLKPLEVELKRLEDLSDEIVKDFQYM-RDREEKMRDTNESTHNRVFYFSIFSMGCLMALAVWQVLYLRRYFKSKK 675
            F   +  K+C  E+I + V VT ++ +          +V      VLY ++      +A+TTE+   +++C   +         + V+ D++ G E   + D   +   L  +E     + +   + V ++Q   R +E + R   E  ++RV  +SI     L+ + V QV+ L+ +F  KK
Sbjct:   47 FELKDNAKQCFYEDIDQGVKVTLDFQVITGGNYDVDCRVKGPHDSVLYNENRKQYDSYAWTTEQRGTYEICFSNEF---STFTHKTVYFDLQVGEEAPLFRDEGTRVVALTQMESACVTIHE-GLKSVDNYQTQHRLQETQDRHQAEVLNSRVNMWSIGETIILVVVGVGQVMLLKSFFSDKK 225          
BLAST of Transmembrane emp24 domain-containing protein 10 vs. Ensembl Yeast
Match: ERV25 (Member of the p24 family involved in ER to Golgi transport; role in misfolded protein quality control; forms a heterotrimeric complex with Erp1, Erp2p, and Emp24, [Source:SGD;Acc:S000004473])

HSP 1 Score: 137.502 bits (345), Expect = 2.813e-39
Identity = 76/206 (36.89%), Postives = 121/206 (58.74%), Query Frame = 1
Query:  106 LYITSAIRFFVTPNG-----------GKKCLKEEIHKNVLVTGEY--DITDAPGQKASIQVTDSKSHVLYQKDDISKG-KFAFTTEEYEMFDVCVETKLMGGGKGPDREVFLDIKHGVETKNYDSLAQAEKLKPLEVELKRLEDLSDEIVKDFQYMRDREEKMRDTNESTHNRVFYFSIFSMGCLMALAVWQVLYLRRYFKSKKLI 681
            L++T+ I   V   G            + C+++ + +  LV  +   D +   GQK ++ V DS  +   +K D +   + AFT      FDVC E +    G+   R + LDI+ G E ++++ ++  EKLKP+EVEL+R+E+++DEIV +  Y+++REE++RDTNEST+ RV  FSI  +  L +L VWQV YL+ YFK+K +I
Sbjct:    6 LWLTTLISLVVAVQGLHFDIAASTDPEQVCIRDFVTEGQLVVADIHSDGSVGDGQKLNLFVRDSVGNEYRRKRDFAGDVRVAFTAPSSTAFDVCFENQAQYRGRSLSRAIELDIESGAEARDWNKISANEKLKPIEVELRRVEEITDEIVDELTYLKNREERLRDTNESTNRRVRNFSILVIIVLSSLGVWQVNYLKNYFKTKHII 211          
BLAST of Transmembrane emp24 domain-containing protein 10 vs. Ensembl Yeast
Match: EMP24 (Component of the p24 complex; role in misfolded protein quality control; binds to GPI anchor proteins and mediates their efficient transport from the ER to the Golgi; integral membrane protein that associates with endoplasmic reticulum-derived COPII-coated vesicles [Source:SGD;Acc:S000003168])

HSP 1 Score: 68.9366 bits (167), Expect = 2.936e-14
Identity = 54/219 (24.66%), Postives = 98/219 (44.75%), Query Frame = 1
Query:   67 MNFYIISLFILNFLYITSAIRFFVTPNGGKKCLKEEIHKNVLVTGEYDITDAPGQKASIQVTD------SKSHVLYQKDDISKGKFAFTTEEYEMFDVCVETKLMGGGKGPDREVFLDIKHGVETK----NYDSLAQAEKLKP----LEVELKRLEDLSDEIVKDFQYMRDREEKMRDTNESTHNRVFYFSIFSMGCLMALAVWQVLYLRRYFKSKKLI 681
            M  +     I  FL+ +++    + P  G++C  E++ K   ++  +   D   Q +S    D       +  VL    D S G+   +      F  C                FL+   G+ETK    N   +   +   P    L+  +++L  L+ E+  +  Y+  RE   R+T EST++RV ++SIF +G ++A +++Q+ YLRR+F+   L+
Sbjct:    1 MASFATKFVIACFLFFSASAHNVLLPAYGRRCFFEDLSKGDELSISFQFGDRNPQSSSQLTGDFIIYGPERHEVLKTVRDTSHGEITLSAPYKGHFQYC----------------FLNENTGIETKDVTFNIHGVVYVDLDDPNTNTLDSAVRKLSKLTREVKDEQSYIVIRERTHRNTAESTNDRVKWWSIFQLGVVIANSLFQIYYLRRFFEVTSLV 203          
BLAST of Transmembrane emp24 domain-containing protein 10 vs. Ensembl Yeast
Match: ERP6 (Member of the p24 family involved in ER to Golgi transport; similar to Emp24p and Erv25p; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; ERP6 has a paralog, ERP1, that arose from the whole genome duplication [Source:SGD;Acc:S000002970])

HSP 1 Score: 67.781 bits (164), Expect = 1.201e-13
Identity = 54/221 (24.43%), Postives = 108/221 (48.87%), Query Frame = 1
Query:   67 MNFYIISLFILNFLYITSAIRFFVTPNGGKKCLKEEIHKNVLVTGEYDITDAPGQKASI---------------QVTDSKSHVLYQKDDISKGKFAFTTEEYEMFDVCVETKLMGG-GKGPDREVFLDIKHGVETKNYDSLAQAEKLKPLEVELKRLEDLSDEIVKDFQYMRDREEKMRDTNESTHNRVFYFSIFSMGCLMALAVWQVLYLRRYFKSKKLI 681
            ++ YI   F+L  L    +  +F    G +KC  +E+ K+ L+ G Y++     + A                 +V D+   V++Q+   S G F+F   E   + +C+++++    GK   +   L+I+  V  +    + + E L+ L  ++  L     +I ++ Q MR+REE  RD +ES ++R  ++++  +  L+ + VWQ+  LR +F  +K++
Sbjct:    2 LSHYIFLAFVL--LPFRVSAFYFYGYGGDRKCFLKELSKDTLLKGSYNLEVYDDKLADYALPSYNDYGIVIDVEEVFDNNHRVVHQQGSPS-GDFSFLALESGEYKICLQSRVNNWVGKTKTK---LEIEFEVGFEAMLDMQRKETLESLHGKVSILNSKIVDIRREQQLMREREESFRDISESVNSRAMWWTVTQVTLLIIICVWQMKSLRSFFVKQKVL 216          
BLAST of Transmembrane emp24 domain-containing protein 10 vs. Ensembl Yeast
Match: ERP1 (Member of the p24 family involved in ER to Golgi transport; role in misfolded protein quality control; forms heterotrimeric complex with Erp2p, Emp24p, and Erv25p; localized to COPII-coated vesicles; ERP1 has a paralog, ERP6, that arose from the whole genome duplication [Source:SGD;Acc:S000002129])

HSP 1 Score: 52.373 bits (124), Expect = 1.787e-8
Identity = 40/198 (20.20%), Postives = 86/198 (43.43%), Query Frame = 1
Query:  130 FFVTPNGGKKCLKEEIHKNVLVTGEY----------DITDAPGQKASIQV----TDSKSHVLYQKDDISKGKFAFTTEEYEMFDVCVETKLMGGGKGPDREVFLDIKHGVETKNYDSLAQAEKLKPLEVELKRLEDLSDEIVKDFQYMRDREEKMRDTNESTHNRVFYFSIFSMGCLMALAVWQVLYLRRYFKSKKLI 681
            ++ T    +KC  +E+ K  L    Y          +  DA  Q   + +    T   +H++  +   + G   F   +     +C++ +  G       ++ ++ + G + K  DS  +A  +  L  ++  L     EI ++ + MRDRE   RD +E+ ++R  ++ +  +  L     WQ+ +L ++F  +K++
Sbjct:   24 YYYTSGAERKCFHKELSKGTLFQATYKAQIYDDQLQNYRDAGAQDFGVLIDIEETFDDNHLVVHQKGSASGDLTFLASDSGEHKICIQPEAGGWLIKAKTKIDVEFQVGSDEK-LDSKGKA-TIDILHAKVNVLNSKIGEIRREQKLMRDREATFRDASEAVNSRAMWWIVIQLIVLAVTCGWQMKHLGKFFVKQKIL 219          
BLAST of Transmembrane emp24 domain-containing protein 10 vs. Ensembl Yeast
Match: ERP5 (Protein with similarity to Emp24p and Erv25p; member of the p24 family involved in ER to Golgi transport [Source:SGD;Acc:S000001152])

HSP 1 Score: 48.521 bits (114), Expect = 3.836e-7
Identity = 51/220 (23.18%), Postives = 99/220 (45.00%), Query Frame = 1
Query:   67 MNFYIISLFILNFLYITSAIR--FFVTPNGGKKCLKEEIHKNVLVTGEYDI--------TDAPGQKASIQVT---DSKSHVLYQKDDISKGKFAFTTEEYEMFDVCVETKLMGGGKGPDREVFLDIKHGVETKNYDSL--AQAEKLKPLEVELKRLEDLSDEIVKDFQYMRDREEKMRDTNESTHNRVFYFSIFSMGCLMALAVWQVLYLRRYFKSKKLI 681
            M + I+    L F  IT A+    F   +G  KC  E + +  L+ G+ D+         + P    +I V    D+   VL QK+  + G   FT  +      C         K     VF++++ G    N ++L   + E +  L+  + +L      I K+   +R++E + R+ +ES ++++  +S+F +  L+    +Q+ YL+ +F  +K++
Sbjct:    1 MKYNIVHGICLLFA-ITQAVGAVHFYAKSGETKCFYEHLSRGNLLIGDLDLYVEKDGLFEEDPESSLTITVDETFDNDHRVLNQKNSHT-GDVTFTALDTGEHRFCFTP--FYSKKSATLRVFIELEIG----NVEALDSKKKEDMNSLKGRVGQLTQRLSSIRKEQDAIREKEAEFRNQSESANSKIMTWSVFQLLILLGTCAFQLRYLKNFFVKQKVV 212          
BLAST of Transmembrane emp24 domain-containing protein 10 vs. Ensembl Nematostella
Match: EDO41239 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S4Z3])

HSP 1 Score: 264.233 bits (674), Expect = 4.024e-88
Identity = 122/202 (60.40%), Postives = 163/202 (80.69%), Query Frame = 1
Query:   79 IISLFILNFLYITSAIRFFVTPNGGKKCLKEEIHKNVLVTGEYDITDAPGQKASIQVTDSKSHVLYQKDDISKGKFAFTTEEYEMFDVCVETKLMGGGKGPDREVFLDIKHGVETKNYDSLAQAEKLKPLEVELKRLEDLSDEIVKDFQYMRDREEKMRDTNESTHNRVFYFSIFSMGCLMALAVWQVLYLRRYFKSKKLIE 684
            ++ L I  ++   S++ F ++ +G +KCLKEE+HK+VLVTGE+ ++DAP QK +++VTDS  HV Y++DD +KGKFAFTT++Y+M++VC +++   GG G DREV ++IKHGVE KNY+ LA+AEKLKP+EVELKRLEDL D IV DF YMR RE++MRDTNESTH+RV YFSIFS+ CL  LA WQ+ YLRR+F +KKLIE
Sbjct:    8 LVPLLICEYILSASSLSFTLS-SGNRKCLKEEVHKDVLVTGEFTLSDAPQQKTNLKVTDSTGHVFYKRDDATKGKFAFTTDDYDMYEVCFDSETSHGG-GSDREVSINIKHGVEAKNYEDLAKAEKLKPMEVELKRLEDLGDAIVNDFAYMRQREQEMRDTNESTHSRVLYFSIFSILCLFGLATWQLFYLRRFFIAKKLIE 207          
BLAST of Transmembrane emp24 domain-containing protein 10 vs. Ensembl Nematostella
Match: EDO41240 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S4Z4])

HSP 1 Score: 128.642 bits (322), Expect = 2.460e-34
Identity = 63/123 (51.22%), Postives = 86/123 (69.92%), Query Frame = 1
Query:  199 GEYDITDAPG-QKASIQVTDSKSHVLYQKDDISKGKFAFTTEEYEMFDVCVETKLMGGGKGPDREVFLDIKHGVETKNYDSLAQAEKLKPLEVELKRLEDLSDEIVKDFQYMRDREEKMRDTN 564
            GEY +++A   QK  IQV D+ +H+LY+ DD  KGKFA TT E   ++VC +    G G    REV ++IKHG E K Y +LAQAEKLKP+++ ++RLED++DEIV  F Y R+REE+ R+TN
Sbjct:   24 GEYVVSEAAAAQKMRIQVLDTANHILYKNDDARKGKFAITTSENNYYEVCFKDNSPGQG-AVRREVSINIKHGTEAKAYQNLAQAEKLKPIKLAMRRLEDMADEIVSSFAYFREREEEQRNTN 145          

HSP 2 Score: 122.479 bits (306), Expect = 4.963e-32
Identity = 70/187 (37.43%), Postives = 109/187 (58.29%), Query Frame = 1
Query:  133 FVTPNGGKKCLKEEIHKNVLVTGEYDITDAPGQKASIQVT----DSKSHVLYQKDDISKGKFAFTTEEYEMFDVCVETKLMGGGKGPDREVFLDIKHGVETKNYDSLAQAEKLKPLEVELKRLEDLSDEIVKDFQYMRDREEKMRDTNESTHNRVFYFSIFSMGCLMALAVWQVLYLRRYFKSKKLI 681
            F      +KCL +   K+ L   +Y+I+    Q +++++T    D    +L+ K++ +KGKFAFT +    FD+C + ++  G  G D  VFL IK G E KNY++LA A+KL+P E+E+ RL D+S E++     + +R E    TNEST  R+ Y  +F    L+ L   Q++YL R+F +KKLI
Sbjct:  147 FKIKAATRKCLTDFAQKDQLFKADYEISH--DQSSTVKITVIDIDVTLQLLFTKENATKGKFAFTFDRDGHFDLCFDNQVRLGS-GSDSIVFLKIKRGSEAKNYENLALAQKLQPQEIEVMRLADMSSEVLTSLGRLINRGEDHLITNESTGARILYLGVFLTMLLVMLTGGQLVYLHRFFAAKKLI 330          
BLAST of Transmembrane emp24 domain-containing protein 10 vs. Ensembl Nematostella
Match: EDO35953 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SK51])

HSP 1 Score: 99.7525 bits (247), Expect = 1.203e-24
Identity = 60/217 (27.65%), Postives = 109/217 (50.23%), Query Frame = 1
Query:   79 IISLFILNFLYITSAIRFFVTPNGGKKCLKEEIHKNVLVTGEYD-----------ITDAPGQKASIQVTDSKSHVLYQKDDISKGKFAFTTEEYEMFDVCVETK-----LMGGGKGPDREVFLDIKHGVETKNYDSLAQAEKLKPLEVELKRLEDLSDEIVKDFQYMRDREEKMRDTNESTHNRVFYFSIFSMGCLMALAVWQVLYLRRYFKSKKLI 681
            ++SL  + ++       +F      KKC  EEI    +V G+Y            +  +PG    ++V D    ++  K   S+G+F FT+       +C+ +      L  GG+     + LDI+ G    +Y  +A  +KL  L++ +++L D  ++I K+  Y R REE+ R T+EST+ RV ++++     L+A   WQ+ +L+ +F++KKL+
Sbjct:    4 VVSLAFIGYMLGNVQALYFHMGETEKKCFIEEIPDETMVIGKYKTQLYDENIKDFLPSSPGIGMHVEVKDPNGKIIMSKYYSSEGRFTFTSHTPGEHVICLHSNSTRWSLWAGGR---LRIHLDIQVGEHANDYAQIAAKDKLTELQLRIRQLLDQVEQISKEQNYQRFREERFRMTSESTNQRVLWWALAQTVILLATGFWQMRHLKGFFEAKKLV 217          
BLAST of Transmembrane emp24 domain-containing protein 10 vs. Ensembl Nematostella
Match: EDO31547 (Transmembrane emp24 domain-containing protein [Source:UniProtKB/Swiss-Prot;Acc:A7SXK3])

HSP 1 Score: 58.9214 bits (141), Expect = 2.436e-10
Identity = 42/200 (21.00%), Postives = 92/200 (46.00%), Query Frame = 1
Query:   85 SLFILNFLYITSAIRFFVTPNGGKKCLKEEIHKNVLVTGEYDITDAPGQKASIQVTDSKSHVLYQKDDISKGKFAFTTEEYEMFDVCVETKLMGGGKGPDREVF-LDIKHGVETKNYDSLAQAEKLKPLEVELKRLEDLSDEIVKDFQYMRDREEKMRDTNESTHNRVFYFSIFSMGCLMALAVWQVLYLRRYFKSKKLI 681
            S  +L FL  +S   F      G++C  +++     +   +++ +       +++      V+Y  +  + GK+ F       ++ C   K+      P    F +DI    +  + +  A  +KL  +   + +L +    +  + +YM  RE   R  N++T++RV ++S F    L+A+ + QV YL+R+F+ ++++
Sbjct:    9 SCIVLMFLARSSLCYFITIDAHGEECFHDKVTSGTKMGLIFEVAEGGFLDIDVKIIGPDQKVIYSGERETSGKYTFAAHMDGTYNYCFSNKM--STMTPKVLKFSMDIGEAPKDTSKEDNAGHDKLSEM---VSQLSEAMTGVKHEQEYMEVRERIHRSINDNTNSRVVWWSFFESLVLVAMTLGQVYYLKRFFEVRRVV 203          
BLAST of Transmembrane emp24 domain-containing protein 10 vs. Ensembl Nematostella
Match: EDO42051 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S2I7])

HSP 1 Score: 45.8246 bits (107), Expect = 7.534e-6
Identity = 40/204 (19.61%), Postives = 86/204 (42.16%), Query Frame = 1
Query:   70 NFYIISLFILNFLYITSAIRFFVTPNGGKKCLKEEIHKNVLVTGEYDITDAPGQKASIQVTDSKSHVLYQKDDISKGKFAFTTEEYEMFDVCVETKLMGGGKGPDREVFLDIKHGVETKNYDSLAQAE-KLKPLEVELKRLEDLSDEIVKDFQ-YMRDREEKMRDTNESTHNRVFYFSIFSMGCLMALAVWQVLYLRRYFKSKK 675
            +F   ++  L+ + ++     F   +  ++C  EE+ K+   T E+ +         + + D     LY           FT E+  ++  C   +         + V+ D + G ET+   ++      L  +E     + + + +I  D+Q + R RE + RD  E  + RV ++S+     ++ + + QV  LR++F  ++
Sbjct:    7 SFVTFTVLALSCILVSCTELTFELEDNARQCFYEELKKDAKATLEFQVITGGNYDVDVILYDINEKELYSVQKKQYDSHTFTVEQPGIYKFCFSNEF---STISHKTVYFDFQSGEETQLTKTMGNHHTALTQMETACVTIHE-NLKIAIDYQTHHRLRESQGRDMAEYLNERVQWWSVGESVLIVIVGICQVFILRQFFAERR 206          
BLAST of Transmembrane emp24 domain-containing protein 10 vs. Ensembl Medaka
Match: tmed10 (transmembrane p24 trafficking protein 10 [Source:NCBI gene;Acc:101167507])

HSP 1 Score: 263.848 bits (673), Expect = 1.767e-87
Identity = 123/189 (65.08%), Postives = 155/189 (82.01%), Query Frame = 1
Query:  121 AIRFFVTPNGGKKCLKEEIHKNVLVTGEYDITDAPGQKASIQVTDSKSHVLYQKDDISKGKFAFTTEEYEMFDVCVETK-LMGGGKGPDREVFLDIKHGVETKNYDSLAQAEKLKPLEVELKRLEDLSDEIVKDFQYMRDREEKMRDTNESTHNRVFYFSIFSMGCLMALAVWQVLYLRRYFKSKKLIE 684
            +I FF+ P   +KCL+EEIHK+VLVTGEYD+T+ P  K  +++TDS +H LY K+D +KGKFAFTTE+Y+MF+VC E+K  +G G+ PD+ V LD+KHGVE KNY+ +A+ EKLKPLEVEL+RLEDLS+ IV DF YM+ REE+MRDTNEST+ RV YFSIFSM CL+ LA WQV YLRR+FK+KKLIE
Sbjct:   20 SISFFL-PVNSRKCLREEIHKDVLVTGEYDLTEQPNTKTHLKITDSSTHTLYSKEDATKGKFAFTTEDYDMFEVCFESKSPLGTGRVPDQLVNLDMKHGVEAKNYEEIAKVEKLKPLEVELRRLEDLSESIVNDFAYMKKREEEMRDTNESTNTRVLYFSIFSMCCLIGLATWQVFYLRRFFKAKKLIE 207          
BLAST of Transmembrane emp24 domain-containing protein 10 vs. Ensembl Medaka
Match: tmed10 (transmembrane p24 trafficking protein 10 [Source:NCBI gene;Acc:101167507])

HSP 1 Score: 262.692 bits (670), Expect = 7.210e-87
Identity = 123/189 (65.08%), Postives = 155/189 (82.01%), Query Frame = 1
Query:  121 AIRFFVTPNGGKKCLKEEIHKNVLVTGEYDITDAPGQKASIQVTDSKSHVLYQKDDISKGKFAFTTEEYEMFDVCVETK-LMGGGKGPDREVFLDIKHGVETKNYDSLAQAEKLKPLEVELKRLEDLSDEIVKDFQYMRDREEKMRDTNESTHNRVFYFSIFSMGCLMALAVWQVLYLRRYFKSKKLIE 684
            +I FF+ P   +KCL+EEIHK+VLVTGEYD+T+ P  K  +++TDS +H LY K+D +KGKFAFTTE+Y+MF+VC E+K  +G G+ PD+ V LD+KHGVE KNY+ +A+ EKLKPLEVEL+RLEDLS+ IV DF YM+ REE+MRDTNEST+ RV YFSIFSM CL+ LA WQV YLRR+FK+KKLIE
Sbjct:   34 SISFFL-PVNSRKCLREEIHKDVLVTGEYDLTEQPNTKTHLKITDSSTHTLYSKEDATKGKFAFTTEDYDMFEVCFESKSPLGTGRVPDQLVNLDMKHGVEAKNYEEIAKVEKLKPLEVELRRLEDLSESIVNDFAYMKKREEEMRDTNESTNTRVLYFSIFSMCCLIGLATWQVFYLRRFFKAKKLIE 221          
BLAST of Transmembrane emp24 domain-containing protein 10 vs. Ensembl Medaka
Match: tmed4 (transmembrane emp24 domain-containing protein 4 [Source:NCBI gene;Acc:101175398])

HSP 1 Score: 106.301 bits (264), Expect = 1.142e-26
Identity = 65/217 (29.95%), Postives = 112/217 (51.61%), Query Frame = 1
Query:   79 IISLFILNFLYITSAIRFFVTPNGGKKCLKEEIHKNVLVTGEYD-----------ITDAPGQKASIQVTDSKSHVLYQKDDISKGKFAFTTEEYEMFDVCVETK-----LMGGGKGPDREVFLDIKHGVETKNYDSLAQAEKLKPLEVELKRLEDLSDEIVKDFQYMRDREEKMRDTNESTHNRVFYFSIFSMGCLMALAVWQVLYLRRYFKSKKLI 681
            + S  +L+++   SA+ F +     KKC  EEI    +V G+Y            +   PG    +++ D  + ++  +   S G+F FT+       +C+ +      L  GGK     V LDI+ G  T NY  +A  +KL  L++ +++L D  ++I K+  Y R REE+ R T+EST+ RV ++SI     L+   +WQ+ +L+ +F++KKL+
Sbjct:    2 LASFLLLSWISSISALYFHIGETE-KKCFIEEIPDETMVIGKYRTQLWDKQSGSFLPATPGLGMHVEIKDPDTKIILSRQYGSDGRFTFTSHTPGEHQICLHSNSTKMALFAGGK---LRVHLDIQVGEHTNNYPEIAAKDKLTELQLRVRQLLDQVEQIQKEQNYQRYREERFRMTSESTNQRVLWWSITQTLILIITGIWQMKHLKSFFEAKKLV 214          
BLAST of Transmembrane emp24 domain-containing protein 10 vs. Ensembl Medaka
Match: tmed4 (transmembrane emp24 domain-containing protein 4 [Source:NCBI gene;Acc:101175398])

HSP 1 Score: 105.145 bits (261), Expect = 3.373e-26
Identity = 64/215 (29.77%), Postives = 111/215 (51.63%), Query Frame = 1
Query:   85 SLFILNFLYITSAIRFFVTPNGGKKCLKEEIHKNVLVTGEYD-----------ITDAPGQKASIQVTDSKSHVLYQKDDISKGKFAFTTEEYEMFDVCVETK-----LMGGGKGPDREVFLDIKHGVETKNYDSLAQAEKLKPLEVELKRLEDLSDEIVKDFQYMRDREEKMRDTNESTHNRVFYFSIFSMGCLMALAVWQVLYLRRYFKSKKLI 681
            +  +L+++   SA+ F +     KKC  EEI    +V G+Y            +   PG    +++ D  + ++  +   S G+F FT+       +C+ +      L  GGK     V LDI+ G  T NY  +A  +KL  L++ +++L D  ++I K+  Y R REE+ R T+EST+ RV ++SI     L+   +WQ+ +L+ +F++KKL+
Sbjct:    9 AFLLLSWISSISALYFHIGETE-KKCFIEEIPDETMVIGKYRTQLWDKQSGSFLPATPGLGMHVEIKDPDTKIILSRQYGSDGRFTFTSHTPGEHQICLHSNSTKMALFAGGK---LRVHLDIQVGEHTNNYPEIAAKDKLTELQLRVRQLLDQVEQIQKEQNYQRYREERFRMTSESTNQRVLWWSITQTLILIITGIWQMKHLKSFFEAKKLV 219          
BLAST of Transmembrane emp24 domain-containing protein 10 vs. Ensembl Medaka
Match: tmed9 (transmembrane emp24 domain-containing protein 9 [Source:NCBI gene;Acc:101173315])

HSP 1 Score: 101.293 bits (251), Expect = 8.567e-25
Identity = 60/192 (31.25%), Postives = 100/192 (52.08%), Query Frame = 1
Query:  154 KKCLKEEIHKNVLVTGEYD-----------ITDAPGQKASIQVTDSKSHVLYQKDDISKGKFAFTTEEYEMFDVCVETK-----LMGGGKGPDREVFLDIKHGVETKNYDSLAQAEKLKPLEVELKRLEDLSDEIVKDFQYMRDREEKMRDTNESTHNRVFYFSIFSMGCLMALAVWQVLYLRRYFKSKKLI 681
            KKC  EEI    ++ G Y            +  +PG    ++V D    V+  +   S+G+F FT+       +C+ +      L  GG      V LDI+ G    NY  +A  +KL  L++ +++L +  D+I K+  Y R REE+ R T+EST+ RV ++SI     L+A+ +WQ+ +L+ +F++KKL+
Sbjct:   30 KKCFIEEIPDETMIIGNYRTQLYDKQKEEYLPASPGLGMFVEVKDPDEKVILSRQYGSEGRFTFTSHTPGEHQICLHSNSSKFSLFVGG---TLRVHLDIQVGEHANNYAEIAAKDKLTELQLRVRQLVEQVDQIQKEQNYQRYREERFRQTSESTNQRVLWWSIVQTLILVAIGIWQMRHLKSFFEAKKLV 218          
BLAST of Transmembrane emp24 domain-containing protein 10 vs. Planmine SMEST
Match: SMESG000024933.1 (SMESG000024933.1)

HSP 1 Score: 427.172 bits (1097), Expect = 5.742e-152
Identity = 206/206 (100.00%), Postives = 206/206 (100.00%), Query Frame = 1
Query:   67 MNFYIISLFILNFLYITSAIRFFVTPNGGKKCLKEEIHKNVLVTGEYDITDAPGQKASIQVTDSKSHVLYQKDDISKGKFAFTTEEYEMFDVCVETKLMGGGKGPDREVFLDIKHGVETKNYDSLAQAEKLKPLEVELKRLEDLSDEIVKDFQYMRDREEKMRDTNESTHNRVFYFSIFSMGCLMALAVWQVLYLRRYFKSKKLIE 684
            MNFYIISLFILNFLYITSAIRFFVTPNGGKKCLKEEIHKNVLVTGEYDITDAPGQKASIQVTDSKSHVLYQKDDISKGKFAFTTEEYEMFDVCVETKLMGGGKGPDREVFLDIKHGVETKNYDSLAQAEKLKPLEVELKRLEDLSDEIVKDFQYMRDREEKMRDTNESTHNRVFYFSIFSMGCLMALAVWQVLYLRRYFKSKKLIE
Sbjct:    1 MNFYIISLFILNFLYITSAIRFFVTPNGGKKCLKEEIHKNVLVTGEYDITDAPGQKASIQVTDSKSHVLYQKDDISKGKFAFTTEEYEMFDVCVETKLMGGGKGPDREVFLDIKHGVETKNYDSLAQAEKLKPLEVELKRLEDLSDEIVKDFQYMRDREEKMRDTNESTHNRVFYFSIFSMGCLMALAVWQVLYLRRYFKSKKLIE 206          
BLAST of Transmembrane emp24 domain-containing protein 10 vs. Planmine SMEST
Match: SMESG000073800.1 (SMESG000073800.1)

HSP 1 Score: 111.309 bits (277), Expect = 1.375e-28
Identity = 66/216 (30.56%), Postives = 117/216 (54.17%), Query Frame = 1
Query:   67 MNFYIISLFILNFLYITSAIRFFVTPNGGKKCLKEEIHKNVLVTGEYD-----------ITDAPGQKASIQVTDSKSHVLYQKDDISKGKFAFTTEEYEMFDVCVETKLMGGGKGPDREVFLDIKHGVETKNYDSLAQAEKLKPLEVELKRLEDLSDEIVKDFQYMRDREEKMRDTNESTHNRVFYFSIFSMGCLMALAVWQVLYLRRYFKSKKLI 681
            M F  IS+F+  F+  T+AI F +     K C  EE+ ++ ++ G+Y            +    G    +++TD +  V+  +   S+G+F  TT     F +C+ +       G    V L+I+ G   ++Y  +A  +KL  L++ +++L D  ++I K+  Y RDRE + RDT+EST++RV YFS+  +G L+ +  WQ+  L+ +F++KKL+
Sbjct:    5 MTFTFISIFLSVFILNTNAIYFHIRETESK-CFIEEVPEDTMIVGKYKTEIFDKSKNVYVPTVSGLGMHVEITDPEKKVVLSRTYSSEGRFVHTTHSSGEFAICLHSNSSVWFGGAKLRVHLEIQTGEHAQDYKEIAAKDKLTDLQLRVRQLIDQVEQITKEQNYQRDREARFRDTSESTNSRVLYFSLVQVGLLVVVGFWQMQNLKSFFRAKKLV 219          
BLAST of Transmembrane emp24 domain-containing protein 10 vs. Planmine SMEST
Match: SMESG000073800.1 (SMESG000073800.1)

HSP 1 Score: 111.309 bits (277), Expect = 1.382e-28
Identity = 66/216 (30.56%), Postives = 117/216 (54.17%), Query Frame = 1
Query:   67 MNFYIISLFILNFLYITSAIRFFVTPNGGKKCLKEEIHKNVLVTGEYD-----------ITDAPGQKASIQVTDSKSHVLYQKDDISKGKFAFTTEEYEMFDVCVETKLMGGGKGPDREVFLDIKHGVETKNYDSLAQAEKLKPLEVELKRLEDLSDEIVKDFQYMRDREEKMRDTNESTHNRVFYFSIFSMGCLMALAVWQVLYLRRYFKSKKLI 681
            M F  IS+F+  F+  T+AI F +     K C  EE+ ++ ++ G+Y            +    G    +++TD +  V+  +   S+G+F  TT     F +C+ +       G    V L+I+ G   ++Y  +A  +KL  L++ +++L D  ++I K+  Y RDRE + RDT+EST++RV YFS+  +G L+ +  WQ+  L+ +F++KKL+
Sbjct:    1 MTFTFISIFLSVFILNTNAIYFHIRETESK-CFIEEVPEDTMIVGKYKTEIFDKSKNVYVPTVSGLGMHVEITDPEKKVVLSRTYSSEGRFVHTTHSSGEFAICLHSNSSVWFGGAKLRVHLEIQTGEHAQDYKEIAAKDKLTDLQLRVRQLIDQVEQITKEQNYQRDREARFRDTSESTNSRVLYFSLVQVGLLVVVGFWQMQNLKSFFRAKKLV 215          
BLAST of Transmembrane emp24 domain-containing protein 10 vs. Planmine SMEST
Match: SMESG000058563.1 (SMESG000058563.1)

HSP 1 Score: 65.855 bits (159), Expect = 1.489e-12
Identity = 36/145 (24.83%), Postives = 71/145 (48.97%), Query Frame = 1
Query:  247 VTDSKSHVLYQKDDISKGKFAFTTEEYEMFDVCVETKLMGGGKGPDREVFLDIKHGVETKNYDSLAQAEKLKPLEVELKRLEDLSDEIVKDFQYMRDREEKMRDTNESTHNRVFYFSIFSMGCLMALAVWQVLYLRRYFKSKKLI 681
            V D    ++  K    +G F+FTT ++  F VC+ T  +   +     ++LD +      +Y      + L   + ++K +  +   I+    Y R +EEK R+T   T++R+ ++S      L+ +  WQ++ L+ +F SKK++
Sbjct:   31 VYDGDGDIIISKAYTEEGFFSFTTHKFGEFKVCISTVSVAWIETVKLRIYLDFETSESADDYMDTLNRQDLDQSKAKIKAIIHIMRNILSQQNYQRIKEEKFRETVAFTNSRLLWWSFMQAFVLLCVGFWQIINLKTFFHSKKIV 175          
BLAST of Transmembrane emp24 domain-containing protein 10 vs. Planmine SMEST
Match: SMESG000058563.1 (SMESG000058563.1)

HSP 1 Score: 65.855 bits (159), Expect = 1.518e-12
Identity = 36/145 (24.83%), Postives = 71/145 (48.97%), Query Frame = 1
Query:  247 VTDSKSHVLYQKDDISKGKFAFTTEEYEMFDVCVETKLMGGGKGPDREVFLDIKHGVETKNYDSLAQAEKLKPLEVELKRLEDLSDEIVKDFQYMRDREEKMRDTNESTHNRVFYFSIFSMGCLMALAVWQVLYLRRYFKSKKLI 681
            V D    ++  K    +G F+FTT ++  F VC+ T  +   +     ++LD +      +Y      + L   + ++K +  +   I+    Y R +EEK R+T   T++R+ ++S      L+ +  WQ++ L+ +F SKK++
Sbjct:   32 VYDGDGDIIISKAYTEEGFFSFTTHKFGEFKVCISTVSVAWIETVKLRIYLDFETSESADDYMDTLNRQDLDQSKAKIKAIIHIMRNILSQQNYQRIKEEKFRETVAFTNSRLLWWSFMQAFVLLCVGFWQIINLKTFFHSKKIV 176          
The following BLAST results are available for this feature:
BLAST of Transmembrane emp24 domain-containing protein 10 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
TMED105.123e-8263.02transmembrane p24 trafficking protein 10 [Source:H... [more]
TMED102.351e-3352.59transmembrane p24 trafficking protein 10 [Source:H... [more]
TMED91.092e-2429.30transmembrane p24 trafficking protein 9 [Source:HG... [more]
TMED41.069e-2331.25transmembrane p24 trafficking protein 4 [Source:HG... [more]
TMED46.906e-927.97transmembrane p24 trafficking protein 4 [Source:HG... [more]
back to top
BLAST of Transmembrane emp24 domain-containing protein 10 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 4
Match NameE-valueIdentityDescription
F47G9.11.395e-8057.71pep chromosome:WBcel235:V:11323965:11326964:-1 gen... [more]
Y60A3A.95.472e-3032.99pep chromosome:WBcel235:V:19946691:19949093:-1 gen... [more]
sel-97.473e-920.49Suppressor/enhancer of lin-12 protein 9 [Source:U... [more]
T08D2.11.084e-628.15pep chromosome:WBcel235:X:162529:163134:-1 gene:WB... [more]
back to top
BLAST of Transmembrane emp24 domain-containing protein 10 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
bai4.975e-7253.73gene:FBgn0045866 transcript:FBtr0084758[more]
eca7.668e-2428.77gene:FBgn0069242 transcript:FBtr0082098[more]
p24-26.167e-1927.72gene:FBgn0053105 transcript:FBtr0082093[more]
p24-26.167e-1927.72gene:FBgn0053105 transcript:FBtr0303038[more]
CHOp245.092e-921.35gene:FBgn0029709 transcript:FBtr0343566[more]
back to top
BLAST of Transmembrane emp24 domain-containing protein 10 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
tmed109.228e-8764.86transmembrane p24 trafficking protein 10 [Source:Z... [more]
tmed109.228e-8764.86transmembrane p24 trafficking protein 10 [Source:Z... [more]
tmed101.213e-8464.13transmembrane p24 trafficking protein 10 [Source:Z... [more]
tmed45.939e-2730.84transmembrane p24 trafficking protein 4 [Source:ZF... [more]
tmed99.763e-2630.63transmembrane p24 trafficking protein 9 [Source:ZF... [more]
back to top
BLAST of Transmembrane emp24 domain-containing protein 10 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
enpp74.943e-8663.68ectonucleotide pyrophosphatase/phosphodiesterase 7... [more]
enpp71.521e-8261.17ectonucleotide pyrophosphatase/phosphodiesterase 7... [more]
shroom14.753e-7660.73shroom family member 1 [Source:Xenbase;Acc:XB-GENE... [more]
tmed43.790e-2531.77transmembrane p24 trafficking protein 4 [Source:NC... [more]
tmed92.250e-2230.73transmembrane p24 trafficking protein 9 [Source:NC... [more]
back to top
BLAST of Transmembrane emp24 domain-containing protein 10 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Tmed103.634e-8263.83transmembrane p24 trafficking protein 10 [Source:M... [more]
Tmed102.004e-5369.49transmembrane p24 trafficking protein 10 [Source:M... [more]
Tmed95.159e-2431.25transmembrane p24 trafficking protein 9 [Source:MG... [more]
Tmed45.696e-2429.30transmembrane p24 trafficking protein 4 [Source:MG... [more]
Tmed92.251e-2132.28transmembrane p24 trafficking protein 9 [Source:MG... [more]
back to top
BLAST of Transmembrane emp24 domain-containing protein 10 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q28735|TMEDA_RABIT8.127e-8264.06Transmembrane emp24 domain-containing protein 10 O... [more]
sp|Q5E971|TMEDA_BOVIN2.305e-8163.54Transmembrane emp24 domain-containing protein 10 O... [more]
sp|P49755|TMEDA_HUMAN2.460e-8163.02Transmembrane emp24 domain-containing protein 10 O... [more]
sp|Q9D1D4|TMEDA_MOUSE2.542e-8163.83Transmembrane emp24 domain-containing protein 10 O... [more]
sp|O35587|TMEDA_MESAU2.927e-8163.54Transmembrane protein Tmp21 OS=Mesocricetus auratu... [more]
back to top
BLAST of Transmembrane emp24 domain-containing protein 10 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A210QCL11.035e-9466.02Transmembrane emp24 domain-containing protein 10 O... [more]
A0A1S3II121.527e-9366.99transmembrane emp24 domain-containing protein 10 O... [more]
V4AC862.009e-9165.69GOLD domain-containing protein OS=Lottia gigantea ... [more]
K1QBY65.414e-9173.45Transmembrane protein Tmp21 OS=Crassostrea gigas O... [more]
T1EJC83.829e-8967.34GOLD domain-containing protein OS=Helobdella robus... [more]
back to top
BLAST of Transmembrane emp24 domain-containing protein 10 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
tmed105.625e-8765.08transmembrane p24 trafficking protein 10 [Source:N... [more]
tmed94.215e-2931.08transmembrane p24 trafficking protein 9 [Source:NC... [more]
tmed93.081e-2830.77transmembrane p24 trafficking protein 9 [Source:NC... [more]
tmed41.855e-2630.84transmembrane p24 trafficking protein 4 [Source:ZF... [more]
si:ch211-255i20.32.524e-1625.34transmembrane emp24 domain-containing protein 11-l... [more]
back to top
BLAST of Transmembrane emp24 domain-containing protein 10 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 3
Match NameE-valueIdentityDescription
ENSPMAT00000001929.12.996e-2331.48pep scaffold:Pmarinus_7.0:GL476868:73855:89088:-1 ... [more]
tmed24.351e-1025.17transmembrane p24 trafficking protein 2 [Source:ZF... [more]
tmed39.639e-622.95transmembrane p24 trafficking protein 3 [Source:ZF... [more]
back to top
BLAST of Transmembrane emp24 domain-containing protein 10 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 5
Match NameE-valueIdentityDescription
ERV252.813e-3936.89Member of the p24 family involved in ER to Golgi t... [more]
EMP242.936e-1424.66Component of the p24 complex; role in misfolded pr... [more]
ERP61.201e-1324.43Member of the p24 family involved in ER to Golgi t... [more]
ERP11.787e-820.20Member of the p24 family involved in ER to Golgi t... [more]
ERP53.836e-723.18Protein with similarity to Emp24p and Erv25p; memb... [more]
back to top
BLAST of Transmembrane emp24 domain-containing protein 10 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO412394.024e-8860.40Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO412402.460e-3451.22Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO359531.203e-2427.65Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO315472.436e-1021.00Transmembrane emp24 domain-containing protein [So... [more]
EDO420517.534e-619.61Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
back to top
BLAST of Transmembrane emp24 domain-containing protein 10 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
tmed101.767e-8765.08transmembrane p24 trafficking protein 10 [Source:N... [more]
tmed107.210e-8765.08transmembrane p24 trafficking protein 10 [Source:N... [more]
tmed41.142e-2629.95transmembrane emp24 domain-containing protein 4 [S... [more]
tmed43.373e-2629.77transmembrane emp24 domain-containing protein 4 [S... [more]
tmed98.567e-2531.25transmembrane emp24 domain-containing protein 9 [S... [more]
back to top
BLAST of Transmembrane emp24 domain-containing protein 10 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000024933.15.742e-152100.00SMESG000024933.1[more]
SMESG000073800.11.375e-2830.56SMESG000073800.1[more]
SMESG000073800.11.382e-2830.56SMESG000073800.1[more]
SMESG000058563.11.489e-1224.83SMESG000058563.1[more]
SMESG000058563.11.518e-1224.83SMESG000058563.1[more]
back to top
Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30028888 ID=SMED30028888|Name=Transmembrane emp24 domain-containing protein 10|organism=Schmidtea mediterranea sexual|type=transcript|length=1116bp
AATTAATAACACATATATTGGATAGTTTTAATCACATTTTAAAAATTAAT
TACGTATTATAGTCGAATGAATTTTTATATTATCAGCCTTTTTATTCTAA
ACTTTCTTTACATAACATCTGCTATTAGATTTTTTGTTACTCCAAATGGA
GGAAAGAAATGTTTAAAGGAAGAAATTCACAAAAATGTGTTAGTTACTGG
TGAATATGATATTACAGATGCACCAGGTCAAAAAGCCTCAATACAAGTAA
CAGATTCTAAATCTCATGTTCTTTATCAAAAAGACGACATTTCAAAAGGC
AAGTTTGCATTTACCACCGAGGAATATGAAATGTTTGATGTTTGTGTCGA
AACAAAATTGATGGGAGGTGGTAAAGGTCCTGACCGAGAAGTTTTCTTAG
ACATTAAGCATGGAGTTGAAACAAAAAATTACGATAGCCTTGCACAAGCA
GAGAAATTGAAGCCCCTCGAAGTGGAATTGAAACGATTGGAAGACCTCAG
CGATGAGATTGTGAAAGATTTCCAGTATATGCGTGACCGAGAAGAGAAAA
TGCGTGATACAAATGAATCCACCCACAACCGAGTGTTCTATTTCTCCATT
TTCTCCATGGGGTGCTTGATGGCGCTCGCCGTTTGGCAGGTTCTTTATTT
GAGGCGATATTTCAAGTCAAAGAAACTGATAGAATAATGAGGTTAGTGTT
GCTACAAATCTTGAAGCAGCGGCAGAGGCGACAGGAGCAACAGCAATTCC
ACAAAATCCGGATTCTGATTATTATCTTAGTGTTGTGTAATAATATTATT
GATTATTAGTTGTGATTTGATTTGTTTTGTTTATTTCCCGTTGTCAATTC
TGTAAACAGGCTGGATTGAAAGGATTGGTTGGTTGTATGCGTGATTGTGT
GTATTATCGTGTCTCTATGCGTGTGTGTGTATATATCGTTATCATGTTGT
TTCAATTACATCAAGTCGTTGCTTCATTCAATCATCTGTATGCATGTGTT
TGTATGTGTCATTTCTGTGTGTGTGTGCGTGTCCGCATCAAGTAAATGTT
ATCAGTCATTCTTCACCATTGTTACCTATTTATAAATAAAATTCAACTGG
ATTCCCAAGATCGGAA
back to top

protein sequence of SMED30028888-orf-1

>SMED30028888-orf-1 ID=SMED30028888-orf-1|Name=SMED30028888-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=207bp
MNFYIISLFILNFLYITSAIRFFVTPNGGKKCLKEEIHKNVLVTGEYDIT
DAPGQKASIQVTDSKSHVLYQKDDISKGKFAFTTEEYEMFDVCVETKLMG
GGKGPDREVFLDIKHGVETKNYDSLAQAEKLKPLEVELKRLEDLSDEIVK
DFQYMRDREEKMRDTNESTHNRVFYFSIFSMGCLMALAVWQVLYLRRYFK
SKKLIE*
back to top
Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000028Category 2 cell
PLANA:0000035Category 3 cell
PLANA:0002032epidermal cell
Vocabulary: INTERPRO
TermDefinition
IPR015720TMP21-related
IPR009038GOLD_dom
Vocabulary: biological process
TermDefinition
GO:0006810transport
GO:0006890retrograde vesicle-mediated transport, Golgi to ER
GO:0015031protein transport
GO:0016192vesicle-mediated transport
GO:0035964COPI-coated vesicle budding
GO:1902003regulation of beta-amyloid formation
Vocabulary: cellular component
TermDefinition
GO:0016021integral component of membrane
GO:0030658transport vesicle membrane
GO:0000139Golgi membrane
GO:0005783endoplasmic reticulum
GO:0005789endoplasmic reticulum membrane
GO:0005794Golgi apparatus
GO:0005886plasma membrane
GO:0016020membrane
GO:0030137COPI-coated vesicle
GO:0030140trans-Golgi network transport vesicle
GO:0030667secretory granule membrane
GO:0031410cytoplasmic vesicle
GO:0033116endoplasmic reticulum-Golgi intermediate compartment membrane
GO:0042470melanosome
GO:0070765gamma-secretase complex
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR009038GOLD domainSMARTSM01190EMP24_GP25L_2coord: 19..200
e-value: 4.7E-63
score: 225.5
IPR009038GOLD domainPFAMPF01105EMP24_GP25Lcoord: 23..200
e-value: 1.6E-49
score: 168.3
IPR009038GOLD domainPROSITEPS50866GOLDcoord: 30..140
score: 13.083
IPR015720TMP21-relatedPANTHERPTHR22811TRANSMEMBRANE EMP24 DOMAIN-CONTAINING PROTEINcoord: 12..205
NoneNo IPR availablePANTHERPTHR22811:SF58TMED10 PROTEINcoord: 12..205
NoneNo IPR availableSIGNALP_EUKSignalP-noTMSignalP-noTMcoord: 1..19
score: 0.844
NoneNo IPR availableTMHMMTMhelixcoord: 5..24
NoneNo IPR availableTMHMMTMhelixcoord: 173..195