Dyslexia-associated protein KIAA0319-like protein
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30028879 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 7
Homology
BLAST of Dyslexia-associated protein KIAA0319-like protein vs. Ensembl Human
Match: KIAA0319 (KIAA0319 [Source:HGNC Symbol;Acc:HGNC:21580]) HSP 1 Score: 306.22 bits (783), Expect = 9.773e-93 Identity = 198/486 (40.74%), Postives = 264/486 (54.32%), Query Frame = 3
Query: 246 KRLKVNIGKNITIFLPKNSVSLVANVSGNP--NQKYDYEWDLVSKPSDQNAGNLEGKNNRELILKNLILGEYQFKLMVKGNNSYGEALVFVFVKPG-------------------------------STDDDKIVSYHWEIIQGPIVKENIMKDDQPMLQLDKTITQGNYTFKLTVKDTSGQLNFTIANLIVLPEKDYPPKSDPGPNMILNLPVNSAILNGSGSTDDKKIVSYEWS--KVSDGLTADIQGVREPILKLSNLQEGTYTFNLKVTDSADQVSNKEVKVYVKPRVNVPPVAKASTTPDGIVTVRLPATEAVLNGSLSSDDDKIVKYQWEQTSGQQKLNIVDGDKPIAFVNDLKIGSFQFRLTVWDSDKQAGSDIVTLKVNENQNQKPKATVVESSEVYYLQPDLIKIDGSKSWDDHKIVKYQWIREDDSLAVGDILEKSYSESVXXXXXXXXXXYKFKLIVYDEEGLYDSAITSLQVFP 1598
K L V+ G N+ I LP N V L A V+ P Y+YEW+L+S P+D G ++ + + L L L +G Y FK+ V N++GE V V VKP STDD +IVSYHWE I GP ++E D P+L+L + GNY+F+LTV D+ G N T A LIV DYPP ++ GPN + LP NS LNG+ S+DD +IV YEWS S+G +QGV+ P L LS +QEG YTF LKVTDS+ Q S V V V+P N PPVA A PD + P A L+GS SSDD IV Y WE G + + + DK IA V L++G++ FRLTV D + + +T+ V + N P+A V L + I +DGS+S DD +IV Y WIR+ S A GD+++ S L LT L+ G+Y F L V D +G D+ +++V P
Sbjct: 333 KELTVSAGDNLIITLPDNEVELKAFVAPAPPVETTYNYEWNLISHPTDYQ-GEIKQGHKQTLNLSQLSVGLYVFKVTVSSENAFGEGFVNVTVKPARRVNLPPVAVVSPQLQELTLPLTSALIDGSQSTDDTEIVSYHWEEINGPFIEEKT-SVDSPVLRLSN-LDPGNYSFRLTVTDSDGATNSTTAALIVNNAVDYPPVANAGPNHTITLPQNSITLNGNQSSDDHQIVLYEWSLGPGSEGKHVVMQGVQTPYLHLSAMQEGDYTFQLKVTDSSRQQSTAVVTVIVQPENNRPPVAVAG--PDKELI--FPVESATLDGSSSSDDHGIVFYHWEHVRGPSAVEMENIDKAIATVTGLQVGTYHFRLTVKDQQGLSSTSTLTVAVKKENNSPPRAR-AGGRHVLVLPNNSITLDGSRSTDDQRIVSYLWIRDGQSPAAGDVIDGSDHSVALQLTNLVEGVYTFHLRVTDSQGASDTDTATVEVQP 810
BLAST of Dyslexia-associated protein KIAA0319-like protein vs. Ensembl Human
Match: KIAA0319 (KIAA0319 [Source:HGNC Symbol;Acc:HGNC:21580]) HSP 1 Score: 305.449 bits (781), Expect = 1.803e-92 Identity = 198/486 (40.74%), Postives = 264/486 (54.32%), Query Frame = 3
Query: 246 KRLKVNIGKNITIFLPKNSVSLVANVSGNP--NQKYDYEWDLVSKPSDQNAGNLEGKNNRELILKNLILGEYQFKLMVKGNNSYGEALVFVFVKPG-------------------------------STDDDKIVSYHWEIIQGPIVKENIMKDDQPMLQLDKTITQGNYTFKLTVKDTSGQLNFTIANLIVLPEKDYPPKSDPGPNMILNLPVNSAILNGSGSTDDKKIVSYEWS--KVSDGLTADIQGVREPILKLSNLQEGTYTFNLKVTDSADQVSNKEVKVYVKPRVNVPPVAKASTTPDGIVTVRLPATEAVLNGSLSSDDDKIVKYQWEQTSGQQKLNIVDGDKPIAFVNDLKIGSFQFRLTVWDSDKQAGSDIVTLKVNENQNQKPKATVVESSEVYYLQPDLIKIDGSKSWDDHKIVKYQWIREDDSLAVGDILEKSYSESVXXXXXXXXXXYKFKLIVYDEEGLYDSAITSLQVFP 1598
K L V+ G N+ I LP N V L A V+ P Y+YEW+L+S P+D G ++ + + L L L +G Y FK+ V N++GE V V VKP STDD +IVSYHWE I GP ++E D P+L+L + GNY+F+LTV D+ G N T A LIV DYPP ++ GPN + LP NS LNG+ S+DD +IV YEWS S+G +QGV+ P L LS +QEG YTF LKVTDS+ Q S V V V+P N PPVA A PD + P A L+GS SSDD IV Y WE G + + + DK IA V L++G++ FRLTV D + + +T+ V + N P+A V L + I +DGS+S DD +IV Y WIR+ S A GD+++ S L LT L+ G+Y F L V D +G D+ +++V P
Sbjct: 288 KELTVSAGDNLIITLPDNEVELKAFVAPAPPVETTYNYEWNLISHPTDYQ-GEIKQGHKQTLNLSQLSVGLYVFKVTVSSENAFGEGFVNVTVKPARRVNLPPVAVVSPQLQELTLPLTSALIDGSQSTDDTEIVSYHWEEINGPFIEEKT-SVDSPVLRLSN-LDPGNYSFRLTVTDSDGATNSTTAALIVNNAVDYPPVANAGPNHTITLPQNSITLNGNQSSDDHQIVLYEWSLGPGSEGKHVVMQGVQTPYLHLSAMQEGDYTFQLKVTDSSRQQSTAVVTVIVQPENNRPPVAVAG--PDKELI--FPVESATLDGSSSSDDHGIVFYHWEHVRGPSAVEMENIDKAIATVTGLQVGTYHFRLTVKDQQGLSSTSTLTVAVKKENNSPPRAR-AGGRHVLVLPNNSITLDGSRSTDDQRIVSYLWIRDGQSPAAGDVIDGSDHSVALQLTNLVEGVYTFHLRVTDSQGASDTDTATVEVQP 765
BLAST of Dyslexia-associated protein KIAA0319-like protein vs. Ensembl Human
Match: KIAA0319 (KIAA0319 [Source:HGNC Symbol;Acc:HGNC:21580]) HSP 1 Score: 305.834 bits (782), Expect = 2.691e-92 Identity = 198/486 (40.74%), Postives = 264/486 (54.32%), Query Frame = 3
Query: 246 KRLKVNIGKNITIFLPKNSVSLVANVSGNP--NQKYDYEWDLVSKPSDQNAGNLEGKNNRELILKNLILGEYQFKLMVKGNNSYGEALVFVFVKPG-------------------------------STDDDKIVSYHWEIIQGPIVKENIMKDDQPMLQLDKTITQGNYTFKLTVKDTSGQLNFTIANLIVLPEKDYPPKSDPGPNMILNLPVNSAILNGSGSTDDKKIVSYEWS--KVSDGLTADIQGVREPILKLSNLQEGTYTFNLKVTDSADQVSNKEVKVYVKPRVNVPPVAKASTTPDGIVTVRLPATEAVLNGSLSSDDDKIVKYQWEQTSGQQKLNIVDGDKPIAFVNDLKIGSFQFRLTVWDSDKQAGSDIVTLKVNENQNQKPKATVVESSEVYYLQPDLIKIDGSKSWDDHKIVKYQWIREDDSLAVGDILEKSYSESVXXXXXXXXXXYKFKLIVYDEEGLYDSAITSLQVFP 1598
K L V+ G N+ I LP N V L A V+ P Y+YEW+L+S P+D G ++ + + L L L +G Y FK+ V N++GE V V VKP STDD +IVSYHWE I GP ++E D P+L+L + GNY+F+LTV D+ G N T A LIV DYPP ++ GPN + LP NS LNG+ S+DD +IV YEWS S+G +QGV+ P L LS +QEG YTF LKVTDS+ Q S V V V+P N PPVA A PD + P A L+GS SSDD IV Y WE G + + + DK IA V L++G++ FRLTV D + + +T+ V + N P+A V L + I +DGS+S DD +IV Y WIR+ S A GD+++ S L LT L+ G+Y F L V D +G D+ +++V P
Sbjct: 333 KELTVSAGDNLIITLPDNEVELKAFVAPAPPVETTYNYEWNLISHPTDYQ-GEIKQGHKQTLNLSQLSVGLYVFKVTVSSENAFGEGFVNVTVKPARRVNLPPVAVVSPQLQELTLPLTSALIDGSQSTDDTEIVSYHWEEINGPFIEEKT-SVDSPVLRLSN-LDPGNYSFRLTVTDSDGATNSTTAALIVNNAVDYPPVANAGPNHTITLPQNSITLNGNQSSDDHQIVLYEWSLGPGSEGKHVVMQGVQTPYLHLSAMQEGDYTFQLKVTDSSRQQSTAVVTVIVQPENNRPPVAVAG--PDKELI--FPVESATLDGSSSSDDHGIVFYHWEHVRGPSAVEMENIDKAIATVTGLQVGTYHFRLTVKDQQGLSSTSTLTVAVKKENNSPPRAR-AGGRHVLVLPNNSITLDGSRSTDDQRIVSYLWIRDGQSPAAGDVIDGSDHSVALQLTNLVEGVYTFHLRVTDSQGASDTDTATVEVQP 810
BLAST of Dyslexia-associated protein KIAA0319-like protein vs. Ensembl Human
Match: KIAA0319 (KIAA0319 [Source:HGNC Symbol;Acc:HGNC:21580]) HSP 1 Score: 305.834 bits (782), Expect = 2.691e-92 Identity = 198/486 (40.74%), Postives = 264/486 (54.32%), Query Frame = 3
Query: 246 KRLKVNIGKNITIFLPKNSVSLVANVSGNP--NQKYDYEWDLVSKPSDQNAGNLEGKNNRELILKNLILGEYQFKLMVKGNNSYGEALVFVFVKPG-------------------------------STDDDKIVSYHWEIIQGPIVKENIMKDDQPMLQLDKTITQGNYTFKLTVKDTSGQLNFTIANLIVLPEKDYPPKSDPGPNMILNLPVNSAILNGSGSTDDKKIVSYEWS--KVSDGLTADIQGVREPILKLSNLQEGTYTFNLKVTDSADQVSNKEVKVYVKPRVNVPPVAKASTTPDGIVTVRLPATEAVLNGSLSSDDDKIVKYQWEQTSGQQKLNIVDGDKPIAFVNDLKIGSFQFRLTVWDSDKQAGSDIVTLKVNENQNQKPKATVVESSEVYYLQPDLIKIDGSKSWDDHKIVKYQWIREDDSLAVGDILEKSYSESVXXXXXXXXXXYKFKLIVYDEEGLYDSAITSLQVFP 1598
K L V+ G N+ I LP N V L A V+ P Y+YEW+L+S P+D G ++ + + L L L +G Y FK+ V N++GE V V VKP STDD +IVSYHWE I GP ++E D P+L+L + GNY+F+LTV D+ G N T A LIV DYPP ++ GPN + LP NS LNG+ S+DD +IV YEWS S+G +QGV+ P L LS +QEG YTF LKVTDS+ Q S V V V+P N PPVA A PD + P A L+GS SSDD IV Y WE G + + + DK IA V L++G++ FRLTV D + + +T+ V + N P+A V L + I +DGS+S DD +IV Y WIR+ S A GD+++ S L LT L+ G+Y F L V D +G D+ +++V P
Sbjct: 333 KELTVSAGDNLIITLPDNEVELKAFVAPAPPVETTYNYEWNLISHPTDYQ-GEIKQGHKQTLNLSQLSVGLYVFKVTVSSENAFGEGFVNVTVKPARRVNLPPVAVVSPQLQELTLPLTSALIDGSQSTDDTEIVSYHWEEINGPFIEEKT-SVDSPVLRLSN-LDPGNYSFRLTVTDSDGATNSTTAALIVNNAVDYPPVANAGPNHTITLPQNSITLNGNQSSDDHQIVLYEWSLGPGSEGKHVVMQGVQTPYLHLSAMQEGDYTFQLKVTDSSRQQSTAVVTVIVQPENNRPPVAVAG--PDKELI--FPVESATLDGSSSSDDHGIVFYHWEHVRGPSAVEMENIDKAIATVTGLQVGTYHFRLTVKDQQGLSSTSTLTVAVKKENNSPPRAR-AGGRHVLVLPNNSITLDGSRSTDDQRIVSYLWIRDGQSPAAGDVIDGSDHSVALQLTNLVEGVYTFHLRVTDSQGASDTDTATVEVQP 810
BLAST of Dyslexia-associated protein KIAA0319-like protein vs. Ensembl Human
Match: KIAA0319 (KIAA0319 [Source:HGNC Symbol;Acc:HGNC:21580]) HSP 1 Score: 305.449 bits (781), Expect = 3.214e-92 Identity = 198/486 (40.74%), Postives = 264/486 (54.32%), Query Frame = 3
Query: 246 KRLKVNIGKNITIFLPKNSVSLVANVSGNP--NQKYDYEWDLVSKPSDQNAGNLEGKNNRELILKNLILGEYQFKLMVKGNNSYGEALVFVFVKPG-------------------------------STDDDKIVSYHWEIIQGPIVKENIMKDDQPMLQLDKTITQGNYTFKLTVKDTSGQLNFTIANLIVLPEKDYPPKSDPGPNMILNLPVNSAILNGSGSTDDKKIVSYEWS--KVSDGLTADIQGVREPILKLSNLQEGTYTFNLKVTDSADQVSNKEVKVYVKPRVNVPPVAKASTTPDGIVTVRLPATEAVLNGSLSSDDDKIVKYQWEQTSGQQKLNIVDGDKPIAFVNDLKIGSFQFRLTVWDSDKQAGSDIVTLKVNENQNQKPKATVVESSEVYYLQPDLIKIDGSKSWDDHKIVKYQWIREDDSLAVGDILEKSYSESVXXXXXXXXXXYKFKLIVYDEEGLYDSAITSLQVFP 1598
K L V+ G N+ I LP N V L A V+ P Y+YEW+L+S P+D G ++ + + L L L +G Y FK+ V N++GE V V VKP STDD +IVSYHWE I GP ++E D P+L+L + GNY+F+LTV D+ G N T A LIV DYPP ++ GPN + LP NS LNG+ S+DD +IV YEWS S+G +QGV+ P L LS +QEG YTF LKVTDS+ Q S V V V+P N PPVA A PD + P A L+GS SSDD IV Y WE G + + + DK IA V L++G++ FRLTV D + + +T+ V + N P+A V L + I +DGS+S DD +IV Y WIR+ S A GD+++ S L LT L+ G+Y F L V D +G D+ +++V P
Sbjct: 324 KELTVSAGDNLIITLPDNEVELKAFVAPAPPVETTYNYEWNLISHPTDYQ-GEIKQGHKQTLNLSQLSVGLYVFKVTVSSENAFGEGFVNVTVKPARRVNLPPVAVVSPQLQELTLPLTSALIDGSQSTDDTEIVSYHWEEINGPFIEEKT-SVDSPVLRLSN-LDPGNYSFRLTVTDSDGATNSTTAALIVNNAVDYPPVANAGPNHTITLPQNSITLNGNQSSDDHQIVLYEWSLGPGSEGKHVVMQGVQTPYLHLSAMQEGDYTFQLKVTDSSRQQSTAVVTVIVQPENNRPPVAVAG--PDKELI--FPVESATLDGSSSSDDHGIVFYHWEHVRGPSAVEMENIDKAIATVTGLQVGTYHFRLTVKDQQGLSSTSTLTVAVKKENNSPPRAR-AGGRHVLVLPNNSITLDGSRSTDDQRIVSYLWIRDGQSPAAGDVIDGSDHSVALQLTNLVEGVYTFHLRVTDSQGASDTDTATVEVQP 801
BLAST of Dyslexia-associated protein KIAA0319-like protein vs. Ensembl Fly
Match: CG7565 (gene:FBgn0035833 transcript:FBtr0076738) HSP 1 Score: 274.633 bits (701), Expect = 3.815e-81 Identity = 185/474 (39.03%), Postives = 255/474 (53.80%), Query Frame = 3
Query: 282 IFLPKNSVSLVANV---SGNPNQKYDYEWDLVSKPSDQNAGNLEGKNNRELILKNLILGEYQFKLMVKGNN-SYGEALVFVFVKP-------------------------------GSTDDDKIVSYHWEIIQGPIVKENIMKDDQPMLQLDKTITQGNYTFKLTVKDTSGQLNFTIANLIVLPEKDYPPKSDPGPNMILNLPVNSAILNGSGSTDDKKIVSYEWSK-VSDGLTA-DIQGVREPILKLSNLQEGTYTFNLKVTDSADQVSNKEVKVYVKPRVNVPPVAKASTTPDGIVTVRLPATEAVLNGSLSSDDDKIVKYQWEQTSGQQKLNIVDGDKPIAFVNDLKIGSFQFRLTVWDSDKQAGSDIVTLKVNENQNQKPKATVVESSEVYYLQPDLIKIDGSKSWDDHKIVKYQWIREDDSLAVGDILEKSYSESVXXXXXXXXXXYKFKLIVYDEEGLYDSAITSLQV 1592
+ LP+ V+L A + KY Y W L+S+P G + ++ ++ L NL G Y FK+ V G+N ++GEA V V P STDDDKI ++HWE+I GPI + ++ + LQLD T + GNYTFKLTV D++ N T A + VL E DY P ++ G +IL LP N+ LNG+ S+DD +IV++EW+K SD A D+Q R P ++LSNL+EG YTF LKVTD + Q S +V V+VKP N PPVA+A + T LP +LNGS S DD I Y W+Q SG I+ + IA L +G ++F LTV D + +D +K+ + +N P A V L I +GSKSWDD +VKY W R++ SLA G I+ + E V++LT L+ G Y F L V D++GL S S+ V
Sbjct: 339 VRLPEQEVTLAAFTVPDEQTSDTKYKYLWTLISQPKGPMNGTISDQSKSKVKLSNLSEGLYTFKVTVTGDNGTFGEATANVTVLPENRINQPPQVIISPREQIIRQPTTNAILDGSTSTDDDKITNWHWEVISGPIGYQPVLPEVN-TLQLDLT-SPGNYTFKLTVTDSNNVTNSTTATIAVLKETDYAPVANAGDAVILYLPNNNVTLNGTASSDDHEIVAWEWTKDASDEAKAVDMQNTRTPYVQLSNLEEGMYTFVLKVTDGSGQSSTAKVHVFVKPPTNSPPVAEAGSN----TTTSLPINWVLLNGSDSKDDIGIKSYLWKQLSGPNNAVILKSNSSIANATSLTLGLYEFELTVADENNNTATDTTWVKIVQERNAAPIANAGGDHTV-TLPATAIYFNGSKSWDDLAVVKYLWTRDEHSLAAGVIVADTDKEPVMILTNLVQGRYVFTLTVSDDQGLTSSDTVSVNV 805 HSP 2 Score: 120.553 bits (301), Expect = 2.350e-28 Identity = 90/265 (33.96%), Postives = 129/265 (48.68%), Query Frame = 3
Query: 525 GSTDDDKIVSYHWEIIQGPIVKENIMKDDQ-PMLQLDKTITQGNYTFKLTVKDTSGQLNFTIANLIVLPEKDYPPKSDPGPNMILNLPVNSAILNGSGSTDDKKIVSYEWSKVSDGLTADIQGVREPILKLSNLQEGTYTFNLKVTDSADQVSNKEVKVYVKPRVNVPPVAKASTTPDGIVTVRLPATEAVLNGSLSSDDDKIVKYQW--EQTSGQQKLNIVDGDK-PIAFVNDLKIGSFQFRLTVWDSDKQAGSDIVTLKVNEN 1307
S+DD +IV++ W K M++ + P +QL + +G YTF L V D SGQ + ++ V P + PP ++ G N +LP+N +LNGS S DD I SY W ++S A I I ++L G Y F L V D + + V + N P+A A G TV LPAT NGS S DD +VKY W ++ S + + D DK P+ + +L G + F LTV D SD V++ V +
Sbjct: 549 ASSDDHEIVAWEWTKDASDEAKAVDMQNTRTPYVQLSN-LEEGMYTFVLKVTDGSGQSSTAKVHVFVKPPTNSPPVAEAGSNTTTSLPINWVLLNGSDSKDDIGIKSYLWKQLSGPNNAVILKSNSSIANATSLTLGLYEFELTVADENNNTATDTTWVKIVQERNAAPIANAG----GDHTVTLPATAIYFNGSKSWDDLAVVKYLWTRDEHSLAAGVIVADTDKEPVMILTNLVQGRYVFTLTVSDDQGLTSSDTVSVNVRRD 808
BLAST of Dyslexia-associated protein KIAA0319-like protein vs. Ensembl Zebrafish
Match: si:ch211-193k19.1 (si:ch211-193k19.1 [Source:ZFIN;Acc:ZDB-GENE-060503-110]) HSP 1 Score: 286.96 bits (733), Expect = 5.123e-87 Identity = 186/471 (39.49%), Postives = 255/471 (54.14%), Query Frame = 3
Query: 252 LKVNIGKNITIFLPKNSVSLVANVSGNP--NQKYDYEWDLVSKPSDQNAGNLEGKNNRELILKNLILGEYQFKLMVKGNNSYGEALVFVFVKP-------------------------------GSTDDDKIVSYHWEIIQGPIVKENIMKDDQPMLQLDKTITQGNYTFKLTVKDTSGQLNFTIANLIVLPEKDYPPKSDPGPNMILNLPVNSAILNGSGSTDDKKIVSYEW--SKVSDGLTADIQGVREPILKLSNLQEGTYTFNLKVTDSADQVSNKEVKVYVKPRVNVPPVAKASTTPDGIVTVRLPATEAVLNGSLSSDDDKIVKYQWEQTSGQQKLNIVDGDKPIAFVNDLKIGSFQFRLTVWDSDKQAGSDIVTLKVNENQNQKPKATVVESSEVYYLQPDLIKIDGSKSWDDHKIVKYQWIREDDSLAVGDILEKSYSESVXXXXXXXXXXYKFKLIVYDEEG 1559
L V+ G+N+ + LP+N V L A V P YD++W L++ P D +G +EGK+ L L L +G Y+F+++V G ++GE V V VKP STDDDK+V +HWE ++GP+ +E D +L L + GNYTF LTV D+ G N T A L+V DY P ++ GPN ++ LP N LNG+ STDD +SYEW S S G ++QGVR P L+LS +QEG YTF L VTDS+ Q +V V V+P N PPVA A PD +T LP L+G S+DD KIV Y W++T G + + + + + +A V L+ G + F LTV D SD V++ V E +Q P A VV S + L +DGS+S DD + Y W RE++S A GD+L S ++VL L L+ G Y F L V D +G
Sbjct: 76 LVVSAGQNVEVTLPRNEVKLSAYVVPAPPTGTNYDFDWRLITHPKDY-SGEMEGKHTMTLKLSKLTVGLYEFEVVVDGEGAHGEGYVNVTVKPEPRVNKPPVAVVSPKYQEISLPTSSTVIDGSRSTDDDKVVLWHWEEVKGPL-REEKASGDTDILTL-TNLVPGNYTFSLTVTDSDGAQNSTQAMLLVNKATDYRPTANAGPNQVITLPHNYITLNGNQSTDDHDNLSYEWSLSPESKGKVVEMQGVRTPTLQLSAMQEGDYTFELTVTDSSGQQDTTQVTVIVQPENNQPPVADAG--PDKELT--LPVDHTTLDGGKSTDDQKIVTYHWKKTKGPEGVKLDNAETVVATVTGLQEGEYIFMLTVTDERNLESSDTVSVIVREENDQPPVAKVVSSPPI-TLPVRTAVLDGSRSSDDKGSISYLWTREENSPAAGDVLNHSDHQAVLFLGNLVEGKYSFTLTVTDSKG 538 HSP 2 Score: 150.599 bits (379), Expect = 3.735e-38 Identity = 118/369 (31.98%), Postives = 176/369 (47.70%), Query Frame = 3
Query: 282 IFLPKNSVSLVANVSGNPNQKYDYEWDLVSKPSDQNAGNLEGKNNRELILKNLILGEYQFKLMVK---GNNSYGEALVFV-----------------FVKPG---------STDDDKIVSYHWEII---QGPIVKENIMKDDQPMLQLDKTITQGNYTFKLTVKDTSGQLNFTIANLIVLPEKDYPPKSDPGPNMILNLPVNSAILNGSGSTDDKKIVSYEWSKVSDGLTADIQGVREPILKLSNLQEGTYTFNLKVTDSADQVSNKEVKVYVKPRVNVPPVAKASTTPDGIVTVRLPATEAVLNGSLSSDDDKIVKYQWEQT----SGQQKLNIVDGDKPIAFVNDLKIGSFQFRLTVWDSDKQAGSD 1280
I LP +S + + S + ++ + W+ V P + + + L L NL+ G Y F L V G + +A++ V P STDD +SY W + +G +V+ ++ P LQL + +G+YTF+LTV D+SGQ + T +IV PE + PP +D GP+ L LPV+ L+G STDD+KIV+Y W K + + ++ LQEG Y F L VTD + S+ V V V+ + PPVAK ++P + LP AVL+GS SSDD + Y W + + LN D + + F+ +L G + F LTV DS + SD
Sbjct: 186 ISLPTSSTVIDGSRSTDDDKVVLWHWEEVKGPLREEKAS---GDTDILTLTNLVPGNYTFSLTVTDSDGAQNSTQAMLLVNKATDYRPTANAGPNQVITLPHNYITLNGNQSTDDHDNLSYEWSLSPESKGKVVEMQGVR--TPTLQL-SAMQEGDYTFELTVTDSSGQQDTTQVTVIVQPENNQPPVADAGPDKELTLPVDHTTLDGGKSTDDQKIVTYHWKKTKGPEGVKLDNAETVVATVTGLQEGEYIFMLTVTDERNLESSDTVSVIVREENDQPPVAKVVSSP----PITLPVRTAVLDGSRSSDDKGSISYLWTREENSPAAGDVLNHSD-HQAVLFLGNLVEGKYSFTLTVTDSKGKTSSD 543 HSP 3 Score: 110.923 bits (276), Expect = 3.591e-25 Identity = 93/297 (31.31%), Postives = 136/297 (45.79%), Query Frame = 3
Query: 225 MVNVLVTKRLKVNIGKNITIFLPKNSVSLVANVSGNPNQKYDYEWDLVSKPSDQNAGNLEGKNNRELILKNLILGEYQFKLMVKGNNSYGEAL-VFVFVKP----------------------------GSTDDDKIVSYHWEIIQGPIVKENIMKDDQPMLQLDKT-ITQGNYTFKLTVKDTSGQLNFTIANLIVLPEKDYPPKSDPGPNMILNLPVNSAILNGSGSTDDKKIVSYEWSKVSDGLTA-DI--QGVREPILKLSNLQEGTYTFNLKVTDSADQVSNKEVKVYVKPRV 1016
+VN R N G N I LP N ++L N S + + YEW L S S ++G L L + G+Y F+L V ++ + V V V+P STDD KIV+YHW+ +GP E + D+ + T + +G Y F LTV D + ++IV E D PP + + + LPV +A+L+GS S+DDK +SY W++ + A D+ + +L L NL EG Y+F L VTDS + S+ V V+P V
Sbjct: 261 LVNKATDYRPTANAGPNQVITLPHNYITLNGNQSTDDHDNLSYEWSL-SPESKGKVVEMQGVRTPTLQLSAMQEGDYTFELTVTDSSGQQDTTQVTVIVQPENNQPPVADAGPDKELTLPVDHTTLDGGKSTDDQKIVTYHWKKTKGP---EGVKLDNAETVVATVTGLQEGEYIFMLTVTDERNLESSDTVSVIVREENDQPPVAKVVSSPPITLPVRTAVLDGSRSSDDKGSISYLWTREENSPAAGDVLNHSDHQAVLFLGNLVEGKYSFTLTVTDSKGKTSSDSGVVDVRPDV 553 HSP 4 Score: 100.908 bits (250), Expect = 7.384e-22 Identity = 83/257 (32.30%), Postives = 126/257 (49.03%), Query Frame = 3
Query: 843 YEWSKVSD--GLTADIQGVREPILKLSNLQEGTYTFNLKVTDSADQVSNKEVKVYVKP--RVNVPPVAKASTTPDGIVTVRLPATEAVLNGSLSSDDDKIVKYQWEQTSGQQKLNIVDGDKPIAFVNDLKIGSFQFRLTVWDSDKQAGSDIVTLKVNENQNQKPKATVVESSEVYYLQPDLIKIDGSKSWDDHKIVKYQWIREDDSLAVGDILE-KSYSESVXXXXXXXXXXYKFKLIVYDEEGLYDSAITSLQVFP 1598
++W ++ + +++G LKLS L G Y F + V D V V VKP RVN PPVA S I LP + V++GS S+DDDK+V + WE+ G + GD I + +L G++ F LTV DSD S L VN+ + +P A ++V L + I ++G++S DDH + Y+W +S G ++E + L L+ + G Y F+L V D G D+ ++ V P
Sbjct: 111 FDWRLITHPKDYSGEMEGKHTMTLKLSKLTVGLYEFEV-VVDGEGAHGEGYVNVTVKPEPRVNKPPVAVVSPKYQEI---SLPTSSTVIDGSRSTDDDKVVLWHWEEVKGPLREEKASGDTDILTLTNLVPGNYTFSLTVTDSDGAQNSTQAMLLVNKATDYRPTAN-AGPNQVITLPHNYITLNGNQSTDDHDNLSYEWSLSPES--KGKVVEMQGVRTPTLQLSAMQEGDYTFELTVTDSSGQQDTTQVTVIVQP 360
BLAST of Dyslexia-associated protein KIAA0319-like protein vs. Ensembl Zebrafish
Match: si:ch211-193k19.1 (si:ch211-193k19.1 [Source:ZFIN;Acc:ZDB-GENE-060503-110]) HSP 1 Score: 278.485 bits (711), Expect = 5.540e-83 Identity = 186/491 (37.88%), Postives = 257/491 (52.34%), Query Frame = 3
Query: 246 KRLKVNIGKNITIFLPKNSVSLVANVSGNP--NQKYDYEWDLVSKPSDQNAGNLEGKNNRELILKNLILGEYQFKLMVKGNNSYGEALVFVFVKP-------------------------------GSTDDDKIVSYHWEIIQGPIVKENIMKDDQPMLQLDKTITQGNYTFK------------------LTVKDTSGQLNFTIANLIVLPEKDYPPKSDPGPNMILNLPVNSAILNGSGSTDDKKIVSYEWS--KVSDGLTADIQGVREPILKLSNLQEGTYTFNLKVTDSADQVSNKEVKVYVKPRVNVPPVAKASTTPDGIVTVRLPATEAVLNGSLSSDDDKIVKYQWEQTSGQQKLNIVDGDKPIAFVNDLKIGSFQFRLTVWDSDKQAGSDIVTLKVNENQNQKPKATVVESSEVYYLQPDLIKIDGSKSWDDHKIVKYQWIREDDSLAVGDILEKSYSESVXXXXXXXXXXYKFKLIVYDEEG 1559
+ L V+ G+N+ + LP+N V L A V P YD++W L++ P D +G +EGK+ L L L +G Y+F+++V G ++GE V V VKP STDDDK+V +HWE ++GP+ +E D +L L + GNYTF+ LTV D+ G N T A L+V DY P ++ GPN ++ LP N LNG+ STDD +SYEWS S G ++QGVR P L+LS +QEG YTF L VTDS+ Q +V V V+P N PPVA A PD +T LP L+G S+DD KIV Y W++T G + + + + + +A V L+ G + F LTV D SD V++ V E +Q P A VV S + L +DGS+S DD + Y W RE++S A GD+L S ++VL L L+ G Y F L V D +G
Sbjct: 205 RELVVSAGQNVEVTLPRNEVKLSAYVVPAPPTGTNYDFDWRLITHPKDY-SGEMEGKHTMTLKLSKLTVGLYEFEVVVDGEGAHGEGYVNVTVKPEPRVNKPPVAVVSPKYQEISLPTSSTVIDGSRSTDDDKVVLWHWEEVKGPL-REEKASGDTDILTL-TNLVPGNYTFRFDYSSSTSQHVCSPQLLILTVTDSDGAQNSTQAMLLVNKATDYRPTANAGPNQVITLPHNYITLNGNQSTDDHDNLSYEWSLSPESKGKVVEMQGVRTPTLQLSAMQEGDYTFELTVTDSSGQQDTTQVTVIVQPENNQPPVADAG--PDKELT--LPVDHTTLDGGKSTDDQKIVTYHWKKTKGPEGVKLDNAETVVATVTGLQEGEYIFMLTVTDERNLESSDTVSVIVREENDQPPVAKVVSSPPI-TLPVRTAVLDGSRSSDDKGSISYLWTREENSPAAGDVLNHSDHQAVLFLGNLVEGKYSFTLTVTDSKG 687 HSP 2 Score: 148.288 bits (373), Expect = 2.277e-37 Identity = 97/258 (37.60%), Postives = 139/258 (53.88%), Query Frame = 3
Query: 528 STDDDKIVSYHWEII---QGPIVKENIMKDDQPMLQLDKTITQGNYTFKLTVKDTSGQLNFTIANLIVLPEKDYPPKSDPGPNMILNLPVNSAILNGSGSTDDKKIVSYEWSKVSDGLTADIQGVREPILKLSNLQEGTYTFNLKVTDSADQVSNKEVKVYVKPRVNVPPVAKASTTPDGIVTVRLPATEAVLNGSLSSDDDKIVKYQWEQT----SGQQKLNIVDGDKPIAFVNDLKIGSFQFRLTVWDSDKQAGSD 1280
STDD +SY W + +G +V+ ++ P LQL + +G+YTF+LTV D+SGQ + T +IV PE + PP +D GP+ L LPV+ L+G STDD+KIV+Y W K + + ++ LQEG Y F L VTD + S+ V V V+ + PPVAK ++P + LP AVL+GS SSDD + Y W + + LN D + + F+ +L G + F LTV DS + SD
Sbjct: 443 STDDHDNLSYEWSLSPESKGKVVEMQGVR--TPTLQL-SAMQEGDYTFELTVTDSSGQQDTTQVTVIVQPENNQPPVADAGPDKELTLPVDHTTLDGGKSTDDQKIVTYHWKKTKGPEGVKLDNAETVVATVTGLQEGEYIFMLTVTDERNLESSDTVSVIVREENDQPPVAKVVSSPP----ITLPVRTAVLDGSRSSDDKGSISYLWTREENSPAAGDVLNHSD-HQAVLFLGNLVEGKYSFTLTVTDSKGKTSSD 692 HSP 3 Score: 112.079 bits (279), Expect = 1.934e-25 Identity = 93/297 (31.31%), Postives = 136/297 (45.79%), Query Frame = 3
Query: 225 MVNVLVTKRLKVNIGKNITIFLPKNSVSLVANVSGNPNQKYDYEWDLVSKPSDQNAGNLEGKNNRELILKNLILGEYQFKLMVKGNNSYGEAL-VFVFVKP----------------------------GSTDDDKIVSYHWEIIQGPIVKENIMKDDQPMLQLDKT-ITQGNYTFKLTVKDTSGQLNFTIANLIVLPEKDYPPKSDPGPNMILNLPVNSAILNGSGSTDDKKIVSYEWSKVSDGLTA-DI--QGVREPILKLSNLQEGTYTFNLKVTDSADQVSNKEVKVYVKPRV 1016
+VN R N G N I LP N ++L N S + + YEW L S S ++G L L + G+Y F+L V ++ + V V V+P STDD KIV+YHW+ +GP E + D+ + T + +G Y F LTV D + ++IV E D PP + + + LPV +A+L+GS S+DDK +SY W++ + A D+ + +L L NL EG Y+F L VTDS + S+ V V+P V
Sbjct: 410 LVNKATDYRPTANAGPNQVITLPHNYITLNGNQSTDDHDNLSYEWSL-SPESKGKVVEMQGVRTPTLQLSAMQEGDYTFELTVTDSSGQQDTTQVTVIVQPENNQPPVADAGPDKELTLPVDHTTLDGGKSTDDQKIVTYHWKKTKGP---EGVKLDNAETVVATVTGLQEGEYIFMLTVTDERNLESSDTVSVIVREENDQPPVAKVVSSPPITLPVRTAVLDGSRSSDDKGSISYLWTREENSPAAGDVLNHSDHQAVLFLGNLVEGKYSFTLTVTDSKGKTSSDSGVVDVRPDV 702 HSP 4 Score: 106.686 bits (265), Expect = 9.199e-24 Identity = 116/371 (31.27%), Postives = 167/371 (45.01%), Query Frame = 3
Query: 555 YHWEIIQGPIVKENIMKDDQPM-LQLDKTITQGNYTFKLTVKDTSGQLNFTIANLIVLPEK--DYPPKSDPGPN-MILNLPVNSAILNGSGSTDDKKIVSYEWSKVSDGLTADIQGVREPILKLSNLQEGTYTFN------------------LKVTDSADQVSNKEVKVYVKPRVNVPPVAKASTTPDGIVTVRLPATEAVLNGSLSSDDDKIVKYQWEQTSGQQKLNIVDGD---KPIAFVNDLKIGSFQFRLTVWDSDKQAGSDIVTLKVNENQNQKPKATVVESSEVYYLQPDLIKIDGSKSWDDHKIVKYQWIREDDSLAVGDILEKSYSESVXXXXXXXXXXYKFKLIVYDEEGLYDSAITSLQV 1592
+ W +I P M+ M L+L K +T G Y F++ V D G N+ V PE + PP + P ++LP +S +++GS STDD K+V + W +V L + IL L+NL G YTF L VTDS ++ + + V + P A A P+ ++T LP LNG+ S+DD + Y+W S + K +V+ P ++ ++ G + F LTV DS Q + VT+ V NQ P A E+ L D +DG KS DD KIV Y W + V L+ + + V +TGL G Y F L V DE L S S+ V
Sbjct: 242 FDWRLITHPKDYSGEMEGKHTMTLKLSK-LTVGLYEFEVVV-DGEGAHGEGYVNVTVKPEPRVNKPPVAVVSPKYQEISLPTSSTVIDGSRSTDDDKVVLWHWEEVKGPLREEKASGDTDILTLTNLVPGNYTFRFDYSSSTSQHVCSPQLLILTVTDSDGAQNSTQAMLLVNKATDYRPTANAG--PNQVIT--LPHNYITLNGNQSTDDHDNLSYEW-SLSPESKGKVVEMQGVRTPTLQLSAMQEGDYTFELTVTDSSGQQDTTQVTVIVQPENNQPPVADAGPDKEL-TLPVDHTTLDGGKSTDDQKIVTYHWKKTKGPEGVK--LDNAET-VVATVTGLQEGEYIFMLTVTDERNLESSDTVSVIV 601
BLAST of Dyslexia-associated protein KIAA0319-like protein vs. Ensembl Zebrafish
Match: si:ch73-215d9.1 (si:ch73-215d9.1 [Source:ZFIN;Acc:ZDB-GENE-100922-40]) HSP 1 Score: 218.394 bits (555), Expect = 2.219e-61 Identity = 165/488 (33.81%), Postives = 243/488 (49.80%), Query Frame = 3
Query: 246 KRLKVNIGKNITIFLPKNSVSLVANVSGNPNQK--YDYEWDLVSKPSDQNAGNLEGKNNRELILKNLILGEYQFKLMVKGNNSYGEALVFVFVKPG--------------------------------STDDDKIVSYHWEIIQGPI-VKENIMKDDQPMLQLDKTITQGNYTFKLTVKDTSGQLNFTIANLIVLPEKDYPPKSDPGPNMILNLPVNSAILNGSGSTDDKKIVSYEWSKVSDGLTADI--QGVREPILKLSNLQEGTYTFNLKVTDSADQVSNKEVKVYVKPRVNVPPVAKASTTPDGIVTVRLPATEAVLNGSLSSDDDKIVKYQWEQTSGQQKLNIVDGDKPIAFVNDLKIGSFQFRLTVWDSDKQAGSDIVTLKVNENQNQKPKATVVESSEVYYLQPDLIKIDGSKSWDDHKIVKYQWIREDDSLAVGDILEKSYSESVXXXXXXXXXXYKFKLIVYDEEGLYDSAITSLQVFP 1598
+ L V+I + LP+N+V L A VS + + Y YEW V P Q +EG++N+ +IL L G Y +++VK + +YGE V + V P S DD IVSY W+ + GP E + ++P+LQL K + G YTF+LTV D+ G + + A L V KD PP + G + ++ LP+N L G+ STDD+ I SY W+ T + Q VR L +S+L+EG YTF L VTDS Q + + V V P N PV A T PD + + LP LNGS S+DD I +YQW+ SG L + D +K +A L+ G ++ +LTV D + S ++++ V E ++ P S L + + + GS S V + W+R++ S A GD+L S E+ L L L+ G Y F+L V D +G +A +++V P
Sbjct: 306 RALTVSIEGPVEAMLPQNTVKLTALVSPDDTAESPYTYEWTFVISPEGQRR-VMEGQHNKSVILSELSEGVYAVRVIVKAHQAYGEGSVDLTVHPAEKINKPPKAVVLPKSQDVLFKKDSVLIINGSESMDDAGIVSYLWKKVDGPFWTPEGPV--NKPVLQL-KNLLPGEYTFELTVSDSEGLSDSSTATLRVSIPKDEPPLARAGTDRVITLPLNHLTLWGNQSTDDQAITSYLWTLHPSSPTRKVTMQDVRSAFLLVSDLEEGQYTFQLTVTDSRGQQDSDTISVTVLP-ANRAPV--AVTGPD--IQLLLPVNSITLNGSGSTDDQAISRYQWDVMSGPPGLKMKDANKAVAIATGLRSGIYKLKLTVVDEQGETDSAVLSITVKEAKS-LPLVAHASGSHTLTLPNNSLVLRGSVSNSGPANVSFLWVRDEQSPAAGDVLYGSDHEASLYLANLVEGTYLFQLRVTDVQGRSSTATATVEVRP 783
BLAST of Dyslexia-associated protein KIAA0319-like protein vs. Ensembl Zebrafish
Match: si:ch73-215d9.1 (si:ch73-215d9.1 [Source:ZFIN;Acc:ZDB-GENE-100922-40]) HSP 1 Score: 218.394 bits (555), Expect = 3.441e-61 Identity = 165/488 (33.81%), Postives = 243/488 (49.80%), Query Frame = 3
Query: 246 KRLKVNIGKNITIFLPKNSVSLVANVSGNPNQK--YDYEWDLVSKPSDQNAGNLEGKNNRELILKNLILGEYQFKLMVKGNNSYGEALVFVFVKPG--------------------------------STDDDKIVSYHWEIIQGPI-VKENIMKDDQPMLQLDKTITQGNYTFKLTVKDTSGQLNFTIANLIVLPEKDYPPKSDPGPNMILNLPVNSAILNGSGSTDDKKIVSYEWSKVSDGLTADI--QGVREPILKLSNLQEGTYTFNLKVTDSADQVSNKEVKVYVKPRVNVPPVAKASTTPDGIVTVRLPATEAVLNGSLSSDDDKIVKYQWEQTSGQQKLNIVDGDKPIAFVNDLKIGSFQFRLTVWDSDKQAGSDIVTLKVNENQNQKPKATVVESSEVYYLQPDLIKIDGSKSWDDHKIVKYQWIREDDSLAVGDILEKSYSESVXXXXXXXXXXYKFKLIVYDEEGLYDSAITSLQVFP 1598
+ L V+I + LP+N+V L A VS + + Y YEW V P Q +EG++N+ +IL L G Y +++VK + +YGE V + V P S DD IVSY W+ + GP E + ++P+LQL K + G YTF+LTV D+ G + + A L V KD PP + G + ++ LP+N L G+ STDD+ I SY W+ T + Q VR L +S+L+EG YTF L VTDS Q + + V V P N PV A T PD + + LP LNGS S+DD I +YQW+ SG L + D +K +A L+ G ++ +LTV D + S ++++ V E ++ P S L + + + GS S V + W+R++ S A GD+L S E+ L L L+ G Y F+L V D +G +A +++V P
Sbjct: 306 RALTVSIEGPVEAMLPQNTVKLTALVSPDDTAESPYTYEWTFVISPEGQRR-VMEGQHNKSVILSELSEGVYAVRVIVKAHQAYGEGSVDLTVHPAEKINKPPKAVVLPKSQDVLFKKDSVLIINGSESMDDAGIVSYLWKKVDGPFWTPEGPV--NKPVLQL-KNLLPGEYTFELTVSDSEGLSDSSTATLRVSIPKDEPPLARAGTDRVITLPLNHLTLWGNQSTDDQAITSYLWTLHPSSPTRKVTMQDVRSAFLLVSDLEEGQYTFQLTVTDSRGQQDSDTISVTVLP-ANRAPV--AVTGPD--IQLLLPVNSITLNGSGSTDDQAISRYQWDVMSGPPGLKMKDANKAVAIATGLRSGIYKLKLTVVDEQGETDSAVLSITVKEAKS-LPLVAHASGSHTLTLPNNSLVLRGSVSNSGPANVSFLWVRDEQSPAAGDVLYGSDHEASLYLANLVEGTYLFQLRVTDVQGRSSTATATVEVRP 783
BLAST of Dyslexia-associated protein KIAA0319-like protein vs. Ensembl Zebrafish
Match: si:ch73-215d9.1 (si:ch73-215d9.1 [Source:ZFIN;Acc:ZDB-GENE-100922-40]) HSP 1 Score: 212.616 bits (540), Expect = 3.325e-59 Identity = 159/477 (33.33%), Postives = 233/477 (48.85%), Query Frame = 3
Query: 273 NITIFLPKNSVSLVANVSGNPNQKYDYEWDLVSKPSDQNAGNLEGKNNRELILKNLILGEYQFKLMVKGNNSYGEALVFVFVKPG--------------------------------STDDDKIVSYHWEIIQGPI-VKENIMKDDQPMLQLDKTITQGNYTFKLTVKDTSGQLNFTIANLIVLPEKDYPPKSDPGPNMILNLPVNSAILNGSGSTDDKKIVSYEWSKVSDGLTADI--QGVREPILKLSNLQEGTYTFNLKVTDSADQVSNKEVKVYVKPRVNVPPVAKASTTPDGIVTVRLPATEAVLNGSLSSDDDKIVKYQWEQTSGQQKLNIVDGDKPIAFVNDLKIGSFQFRLTVWDSDKQAGSDIVTLKVNENQNQKPKATVVESSEVYYLQPDLIKIDGSKSWDDHKIVKYQWIREDDSLAVGDILEKSYSESVXXXXXXXXXXYKFKLIVYDEEGLYDSAITSLQVFP 1598
N + P N+ + S P Y YEW V P Q +EG++N+ +IL L G Y +++VK + +YGE V + V P S DD IVSY W+ + GP E + ++P+LQL K + G YTF+LTV D+ G + + A L V KD PP + G + ++ LP+N L G+ STDD+ I SY W+ T + Q VR L +S+L+EG YTF L VTDS Q + + V V P N PV A T PD + + LP LNGS S+DD I +YQW+ SG L + D +K +A L+ G ++ +LTV D + S ++++ V E ++ P S L + + + GS S V + W+R++ S A GD+L S E+ L L L+ G Y F+L V D +G +A +++V P
Sbjct: 284 NGSFITPANTEATPQMTSEQPESPYTYEWTFVISPEGQRR-VMEGQHNKSVILSELSEGVYAVRVIVKAHQAYGEGSVDLTVHPAEKINKPPKAVVLPKSQDVLFKKDSVLIINGSESMDDAGIVSYLWKKVDGPFWTPEGPV--NKPVLQL-KNLLPGEYTFELTVSDSEGLSDSSTATLRVSIPKDEPPLARAGTDRVITLPLNHLTLWGNQSTDDQAITSYLWTLHPSSPTRKVTMQDVRSAFLLVSDLEEGQYTFQLTVTDSRGQQDSDTISVTVLP-ANRAPV--AVTGPD--IQLLLPVNSITLNGSGSTDDQAISRYQWDVMSGPPGLKMKDANKAVAIATGLRSGIYKLKLTVVDEQGETDSAVLSITVKEAKS-LPLVAHASGSHTLTLPNNSLVLRGSVSNSGPANVSFLWVRDEQSPAAGDVLYGSDHEASLYLANLVEGTYLFQLRVTDVQGRSSTATATVEVRP 750
BLAST of Dyslexia-associated protein KIAA0319-like protein vs. Ensembl Xenopus
Match: KIAA0319L (kiaa0319 like [Source:NCBI gene;Acc:100494286]) HSP 1 Score: 309.686 bits (792), Expect = 4.860e-96 Identity = 200/488 (40.98%), Postives = 278/488 (56.97%), Query Frame = 3
Query: 240 VTKRLKVNIGKNITIFLPKNSVSLVANVSGNP--NQKYDYEWDLVSKPSDQNAGNLEGKNNRELILKNLILGEYQFKLMVKGNNSYGEALVFVFVKPG-------------------------------STDDDKIVSYHWEIIQGPIVKENIMKDDQPMLQLDKTITQGNYTFKLTVKDTSGQLNFTIANLIVLPEKDYPPKSDPGPNMILNLPVNSAILNGSGSTDDKKIVSYEW--SKVSDGLTADIQGVREPILKLSNLQEGTYTFNLKVTDSADQVSNKEVKVYVKPRVNVPPVAKASTTPDGIVTVRLPATEAVLNGSLSSDDDKIVKYQWEQTSGQQKLNIVDGDKPIAFVNDLKIGSFQFRLTVWDSDKQAGSDIVTLKVNENQNQKPKATVVESSEVYYLQPDLIKIDGSKSWDDHKIVKYQWIREDDSLAVGDILEKSYSESVXXXXXXXXXXYKFKLIVYDEEGLYDSAITSLQVFP 1598
VT +L V+ G ++ + LPKN V L A V P + Y Y+W L++ P+D +G +EGK+++EL L L G Y+FK++VKG N++GE V V V P STDD+KIVSY+WE ++GP+ +E + + P+L+L + GNYTF+LTV D+ G N T ANL V DYPP ++ G N ++ LP NS +L G+ STDD IVSYEW S S G ++QGVR L+LS LQEG YTF+L VTDSA Q S EV V V+P N PP A A PD +T LP L+GS S+DD I Y WE+T G + I + + A V+ L++G+++F LTV D V++ V E N+ P A + + V L + ++DG+KS+DD IV YQW R++ S A G++L S SVL L+ L+ G+Y F L V D +G DS +++V P
Sbjct: 33 VTNKLVVSAGDSVEVTLPKNEVQLNAFVVPEPPEGKTYTYDWRLITHPTDY-SGEMEGKHSQELKLSKLTAGLYEFKVIVKGENAHGEGFVNVTVNPKPRVNQPPTAIVSPRYQEISLPTTSTFIDGSQSTDDEKIVSYYWEELKGPLREEKVTA-ETPVLKLSN-LVPGNYTFRLTVTDSDGAQNSTTANLTVSKAVDYPPVANAGANQVITLPKNSIVLFGNLSTDDHGIVSYEWSLSPSSKGNVMEMQGVRTANLQLSALQEGDYTFHLTVTDSAGQQSTSEVTVIVQPENNKPPEADAG--PDKELT--LPVDSTTLDGSRSTDDQGISSYLWEKTKGPDGVKITNSNSSTATVSGLQVGTYEFTLTVKDERDLQSQSTVSVIVREEINKPPVAKIA-GNVVITLPSNTAELDGTKSFDDKGIVSYQWERDEGSPAAGEVLNGSDCHSVLFLSNLVEGIYSFHLKVTDAKGETDSDRATVEVKP 512
BLAST of Dyslexia-associated protein KIAA0319-like protein vs. Ensembl Xenopus
Match: KIAA0319L (kiaa0319 like [Source:NCBI gene;Acc:100494286]) HSP 1 Score: 310.842 bits (795), Expect = 3.672e-95 Identity = 200/488 (40.98%), Postives = 278/488 (56.97%), Query Frame = 3
Query: 240 VTKRLKVNIGKNITIFLPKNSVSLVANVSGNP--NQKYDYEWDLVSKPSDQNAGNLEGKNNRELILKNLILGEYQFKLMVKGNNSYGEALVFVFVKPG-------------------------------STDDDKIVSYHWEIIQGPIVKENIMKDDQPMLQLDKTITQGNYTFKLTVKDTSGQLNFTIANLIVLPEKDYPPKSDPGPNMILNLPVNSAILNGSGSTDDKKIVSYEW--SKVSDGLTADIQGVREPILKLSNLQEGTYTFNLKVTDSADQVSNKEVKVYVKPRVNVPPVAKASTTPDGIVTVRLPATEAVLNGSLSSDDDKIVKYQWEQTSGQQKLNIVDGDKPIAFVNDLKIGSFQFRLTVWDSDKQAGSDIVTLKVNENQNQKPKATVVESSEVYYLQPDLIKIDGSKSWDDHKIVKYQWIREDDSLAVGDILEKSYSESVXXXXXXXXXXYKFKLIVYDEEGLYDSAITSLQVFP 1598
VT +L V+ G ++ + LPKN V L A V P + Y Y+W L++ P+D +G +EGK+++EL L L G Y+FK++VKG N++GE V V V P STDD+KIVSY+WE ++GP+ +E + + P+L+L + GNYTF+LTV D+ G N T ANL V DYPP ++ G N ++ LP NS +L G+ STDD IVSYEW S S G ++QGVR L+LS LQEG YTF+L VTDSA Q S EV V V+P N PP A A PD +T LP L+GS S+DD I Y WE+T G + I + + A V+ L++G+++F LTV D V++ V E N+ P A + + V L + ++DG+KS+DD IV YQW R++ S A G++L S SVL L+ L+ G+Y F L V D +G DS +++V P
Sbjct: 172 VTNKLVVSAGDSVEVTLPKNEVQLNAFVVPEPPEGKTYTYDWRLITHPTDY-SGEMEGKHSQELKLSKLTAGLYEFKVIVKGENAHGEGFVNVTVNPKPRVNQPPTAIVSPRYQEISLPTTSTFIDGSQSTDDEKIVSYYWEELKGPLREEKVTA-ETPVLKLSN-LVPGNYTFRLTVTDSDGAQNSTTANLTVSKAVDYPPVANAGANQVITLPKNSIVLFGNLSTDDHGIVSYEWSLSPSSKGNVMEMQGVRTANLQLSALQEGDYTFHLTVTDSAGQQSTSEVTVIVQPENNKPPEADAG--PDKELT--LPVDSTTLDGSRSTDDQGISSYLWEKTKGPDGVKITNSNSSTATVSGLQVGTYEFTLTVKDERDLQSQSTVSVIVREEINKPPVAKIA-GNVVITLPSNTAELDGTKSFDDKGIVSYQWERDEGSPAAGEVLNGSDCHSVLFLSNLVEGIYSFHLKVTDAKGETDSDRATVEVKP 651
BLAST of Dyslexia-associated protein KIAA0319-like protein vs. Ensembl Xenopus
Match: KIAA0319L (kiaa0319 like [Source:NCBI gene;Acc:100494286]) HSP 1 Score: 311.227 bits (796), Expect = 7.134e-95 Identity = 200/488 (40.98%), Postives = 278/488 (56.97%), Query Frame = 3
Query: 240 VTKRLKVNIGKNITIFLPKNSVSLVANVSGNP--NQKYDYEWDLVSKPSDQNAGNLEGKNNRELILKNLILGEYQFKLMVKGNNSYGEALVFVFVKPG-------------------------------STDDDKIVSYHWEIIQGPIVKENIMKDDQPMLQLDKTITQGNYTFKLTVKDTSGQLNFTIANLIVLPEKDYPPKSDPGPNMILNLPVNSAILNGSGSTDDKKIVSYEW--SKVSDGLTADIQGVREPILKLSNLQEGTYTFNLKVTDSADQVSNKEVKVYVKPRVNVPPVAKASTTPDGIVTVRLPATEAVLNGSLSSDDDKIVKYQWEQTSGQQKLNIVDGDKPIAFVNDLKIGSFQFRLTVWDSDKQAGSDIVTLKVNENQNQKPKATVVESSEVYYLQPDLIKIDGSKSWDDHKIVKYQWIREDDSLAVGDILEKSYSESVXXXXXXXXXXYKFKLIVYDEEGLYDSAITSLQVFP 1598
VT +L V+ G ++ + LPKN V L A V P + Y Y+W L++ P+D +G +EGK+++EL L L G Y+FK++VKG N++GE V V V P STDD+KIVSY+WE ++GP+ +E + + P+L+L + GNYTF+LTV D+ G N T ANL V DYPP ++ G N ++ LP NS +L G+ STDD IVSYEW S S G ++QGVR L+LS LQEG YTF+L VTDSA Q S EV V V+P N PP A A PD +T LP L+GS S+DD I Y WE+T G + I + + A V+ L++G+++F LTV D V++ V E N+ P A + + V L + ++DG+KS+DD IV YQW R++ S A G++L S SVL L+ L+ G+Y F L V D +G DS +++V P
Sbjct: 242 VTNKLVVSAGDSVEVTLPKNEVQLNAFVVPEPPEGKTYTYDWRLITHPTDY-SGEMEGKHSQELKLSKLTAGLYEFKVIVKGENAHGEGFVNVTVNPKPRVNQPPTAIVSPRYQEISLPTTSTFIDGSQSTDDEKIVSYYWEELKGPLREEKVTA-ETPVLKLSN-LVPGNYTFRLTVTDSDGAQNSTTANLTVSKAVDYPPVANAGANQVITLPKNSIVLFGNLSTDDHGIVSYEWSLSPSSKGNVMEMQGVRTANLQLSALQEGDYTFHLTVTDSAGQQSTSEVTVIVQPENNKPPEADAG--PDKELT--LPVDSTTLDGSRSTDDQGISSYLWEKTKGPDGVKITNSNSSTATVSGLQVGTYEFTLTVKDERDLQSQSTVSVIVREEINKPPVAKIA-GNVVITLPSNTAELDGTKSFDDKGIVSYQWERDEGSPAAGEVLNGSDCHSVLFLSNLVEGIYSFHLKVTDAKGETDSDRATVEVKP 721
BLAST of Dyslexia-associated protein KIAA0319-like protein vs. Ensembl Xenopus
Match: KIAA0319L (kiaa0319 like [Source:NCBI gene;Acc:100494286]) HSP 1 Score: 310.071 bits (793), Expect = 8.250e-95 Identity = 200/488 (40.98%), Postives = 278/488 (56.97%), Query Frame = 3
Query: 240 VTKRLKVNIGKNITIFLPKNSVSLVANVSGNP--NQKYDYEWDLVSKPSDQNAGNLEGKNNRELILKNLILGEYQFKLMVKGNNSYGEALVFVFVKPG-------------------------------STDDDKIVSYHWEIIQGPIVKENIMKDDQPMLQLDKTITQGNYTFKLTVKDTSGQLNFTIANLIVLPEKDYPPKSDPGPNMILNLPVNSAILNGSGSTDDKKIVSYEW--SKVSDGLTADIQGVREPILKLSNLQEGTYTFNLKVTDSADQVSNKEVKVYVKPRVNVPPVAKASTTPDGIVTVRLPATEAVLNGSLSSDDDKIVKYQWEQTSGQQKLNIVDGDKPIAFVNDLKIGSFQFRLTVWDSDKQAGSDIVTLKVNENQNQKPKATVVESSEVYYLQPDLIKIDGSKSWDDHKIVKYQWIREDDSLAVGDILEKSYSESVXXXXXXXXXXYKFKLIVYDEEGLYDSAITSLQVFP 1598
VT +L V+ G ++ + LPKN V L A V P + Y Y+W L++ P+D +G +EGK+++EL L L G Y+FK++VKG N++GE V V V P STDD+KIVSY+WE ++GP+ +E + + P+L+L + GNYTF+LTV D+ G N T ANL V DYPP ++ G N ++ LP NS +L G+ STDD IVSYEW S S G ++QGVR L+LS LQEG YTF+L VTDSA Q S EV V V+P N PP A A PD +T LP L+GS S+DD I Y WE+T G + I + + A V+ L++G+++F LTV D V++ V E N+ P A + + V L + ++DG+KS+DD IV YQW R++ S A G++L S SVL L+ L+ G+Y F L V D +G DS +++V P
Sbjct: 199 VTNKLVVSAGDSVEVTLPKNEVQLNAFVVPEPPEGKTYTYDWRLITHPTDY-SGEMEGKHSQELKLSKLTAGLYEFKVIVKGENAHGEGFVNVTVNPKPRVNQPPTAIVSPRYQEISLPTTSTFIDGSQSTDDEKIVSYYWEELKGPLREEKVTAET-PVLKLSN-LVPGNYTFRLTVTDSDGAQNSTTANLTVSKAVDYPPVANAGANQVITLPKNSIVLFGNLSTDDHGIVSYEWSLSPSSKGNVMEMQGVRTANLQLSALQEGDYTFHLTVTDSAGQQSTSEVTVIVQPENNKPPEADAG--PDKELT--LPVDSTTLDGSRSTDDQGISSYLWEKTKGPDGVKITNSNSSTATVSGLQVGTYEFTLTVKDERDLQSQSTVSVIVREEINKPPVAKIA-GNVVITLPSNTAELDGTKSFDDKGIVSYQWERDEGSPAAGEVLNGSDCHSVLFLSNLVEGIYSFHLKVTDAKGETDSDRATVEVKP 678
BLAST of Dyslexia-associated protein KIAA0319-like protein vs. Ensembl Xenopus
Match: KIAA0319L (kiaa0319 like [Source:NCBI gene;Acc:100494286]) HSP 1 Score: 310.457 bits (794), Expect = 9.417e-95 Identity = 200/488 (40.98%), Postives = 278/488 (56.97%), Query Frame = 3
Query: 240 VTKRLKVNIGKNITIFLPKNSVSLVANVSGNP--NQKYDYEWDLVSKPSDQNAGNLEGKNNRELILKNLILGEYQFKLMVKGNNSYGEALVFVFVKPG-------------------------------STDDDKIVSYHWEIIQGPIVKENIMKDDQPMLQLDKTITQGNYTFKLTVKDTSGQLNFTIANLIVLPEKDYPPKSDPGPNMILNLPVNSAILNGSGSTDDKKIVSYEW--SKVSDGLTADIQGVREPILKLSNLQEGTYTFNLKVTDSADQVSNKEVKVYVKPRVNVPPVAKASTTPDGIVTVRLPATEAVLNGSLSSDDDKIVKYQWEQTSGQQKLNIVDGDKPIAFVNDLKIGSFQFRLTVWDSDKQAGSDIVTLKVNENQNQKPKATVVESSEVYYLQPDLIKIDGSKSWDDHKIVKYQWIREDDSLAVGDILEKSYSESVXXXXXXXXXXYKFKLIVYDEEGLYDSAITSLQVFP 1598
VT +L V+ G ++ + LPKN V L A V P + Y Y+W L++ P+D +G +EGK+++EL L L G Y+FK++VKG N++GE V V V P STDD+KIVSY+WE ++GP+ +E + + P+L+L + GNYTF+LTV D+ G N T ANL V DYPP ++ G N ++ LP NS +L G+ STDD IVSYEW S S G ++QGVR L+LS LQEG YTF+L VTDSA Q S EV V V+P N PP A A PD +T LP L+GS S+DD I Y WE+T G + I + + A V+ L++G+++F LTV D V++ V E N+ P A + + V L + ++DG+KS+DD IV YQW R++ S A G++L S SVL L+ L+ G+Y F L V D +G DS +++V P
Sbjct: 210 VTNKLVVSAGDSVEVTLPKNEVQLNAFVVPEPPEGKTYTYDWRLITHPTDY-SGEMEGKHSQELKLSKLTAGLYEFKVIVKGENAHGEGFVNVTVNPKPRVNQPPTAIVSPRYQEISLPTTSTFIDGSQSTDDEKIVSYYWEELKGPLREEKVTA-ETPVLKLSN-LVPGNYTFRLTVTDSDGAQNSTTANLTVSKAVDYPPVANAGANQVITLPKNSIVLFGNLSTDDHGIVSYEWSLSPSSKGNVMEMQGVRTANLQLSALQEGDYTFHLTVTDSAGQQSTSEVTVIVQPENNKPPEADAG--PDKELT--LPVDSTTLDGSRSTDDQGISSYLWEKTKGPDGVKITNSNSSTATVSGLQVGTYEFTLTVKDERDLQSQSTVSVIVREEINKPPVAKIA-GNVVITLPSNTAELDGTKSFDDKGIVSYQWERDEGSPAAGEVLNGSDCHSVLFLSNLVEGIYSFHLKVTDAKGETDSDRATVEVKP 689
BLAST of Dyslexia-associated protein KIAA0319-like protein vs. Ensembl Mouse
Match: AU040320 (expressed sequence AU040320 [Source:MGI Symbol;Acc:MGI:2140475]) HSP 1 Score: 302.368 bits (773), Expect = 2.453e-91 Identity = 195/488 (39.96%), Postives = 269/488 (55.12%), Query Frame = 3
Query: 240 VTKRLKVNIGKNITIFLPKNSVSLVANV--SGNPNQKYDYEWDLVSKPSDQNAGNLEGKNNRELILKNLILGEYQFKLMVKGNNSYGEALVFVFVKP-------------------------------GSTDDDKIVSYHWEIIQGPIVKENIMKDDQPMLQLDKTITQGNYTFKLTVKDTSGQLNFTIANLIVLPEKDYPPKSDPGPNMILNLPVNSAILNGSGSTDDKKIVSYEW--SKVSDGLTADIQGVREPILKLSNLQEGTYTFNLKVTDSADQVSNKEVKVYVKPRVNVPPVAKASTTPDGIVTVRLPATEAVLNGSLSSDDDKIVKYQWEQTSGQQKLNIVDGDKPIAFVNDLKIGSFQFRLTVWDSDKQAGSDIVTLKVNENQNQKPKATVVESSEVYYLQPDLIKIDGSKSWDDHKIVKYQWIREDDSLAVGDILEKSYSESVXXXXXXXXXXYKFKLIVYDEEGLYDSAITSLQVFP 1598
V K L V+ GK++ I LPKN V L A V P + Y Y+W L++ P+D +G +E K+++ L L L G Y+FK+ V G N++GE V V VKP STDDDKIV YHWE ++GP+ +E I +D +L+L K + GNYTF LTV D+ G N T A+L V DYPP ++ GPN ++ LP NS L G+ STDD I SYEW S S G ++QGVR P L+LS +QEG YT+ L VTD+A Q + +V V V+P N PP A A PD +T LP L+GS S+DD ++V Y WEQ+ G + + + + +A V L++G++ F LTV D V + V E N+ P A + + V L ++DGS+S DD IV Y W R++ S A G++L S VL L+ L+ G Y F L V D +G D+ T+++V P
Sbjct: 304 VVKELVVSAGKSVQITLPKNEVQLNAFVLPEAEPGETYTYDWQLITHPTDY-SGEVERKHSQSLQLSKLTPGLYEFKVTVDGQNAHGEGYVNVTVKPEPRKNRPPVAVVSPQFQEISLPTTSTIIDGSQSTDDDKIVQYHWEELKGPLREEKI-SEDTAILKLSK-LVPGNYTFSLTVVDSDGATNSTTASLTVNKAVDYPPVANAGPNQVITLPQNSITLFGNQSTDDHGITSYEWSLSPSSKGKVVEMQGVRTPALQLSAMQEGDYTYQLTVTDTAGQQATAQVTVIVQPENNKPPQADAG--PDKELT--LPVDSTTLDGSKSTDDQRVVSYLWEQSRGPDGVQLENANSSVATVTGLQVGTYVFTLTVKDERNLQSQSSVNVIVKEEINKPPVAKIA-GNVVVTLPTSTAELDGSRSSDDKGIVSYLWTRDETSPAAGEVLNHSDHHPVLFLSNLVEGTYTFHLKVTDAKGESDTDRTTVEVKP 783
BLAST of Dyslexia-associated protein KIAA0319-like protein vs. Ensembl Mouse
Match: AU040320 (expressed sequence AU040320 [Source:MGI Symbol;Acc:MGI:2140475]) HSP 1 Score: 302.368 bits (773), Expect = 3.838e-91 Identity = 195/488 (39.96%), Postives = 269/488 (55.12%), Query Frame = 3
Query: 240 VTKRLKVNIGKNITIFLPKNSVSLVANV--SGNPNQKYDYEWDLVSKPSDQNAGNLEGKNNRELILKNLILGEYQFKLMVKGNNSYGEALVFVFVKP-------------------------------GSTDDDKIVSYHWEIIQGPIVKENIMKDDQPMLQLDKTITQGNYTFKLTVKDTSGQLNFTIANLIVLPEKDYPPKSDPGPNMILNLPVNSAILNGSGSTDDKKIVSYEW--SKVSDGLTADIQGVREPILKLSNLQEGTYTFNLKVTDSADQVSNKEVKVYVKPRVNVPPVAKASTTPDGIVTVRLPATEAVLNGSLSSDDDKIVKYQWEQTSGQQKLNIVDGDKPIAFVNDLKIGSFQFRLTVWDSDKQAGSDIVTLKVNENQNQKPKATVVESSEVYYLQPDLIKIDGSKSWDDHKIVKYQWIREDDSLAVGDILEKSYSESVXXXXXXXXXXYKFKLIVYDEEGLYDSAITSLQVFP 1598
V K L V+ GK++ I LPKN V L A V P + Y Y+W L++ P+D +G +E K+++ L L L G Y+FK+ V G N++GE V V VKP STDDDKIV YHWE ++GP+ +E I +D +L+L K + GNYTF LTV D+ G N T A+L V DYPP ++ GPN ++ LP NS L G+ STDD I SYEW S S G ++QGVR P L+LS +QEG YT+ L VTD+A Q + +V V V+P N PP A A PD +T LP L+GS S+DD ++V Y WEQ+ G + + + + +A V L++G++ F LTV D V + V E N+ P A + + V L ++DGS+S DD IV Y W R++ S A G++L S VL L+ L+ G Y F L V D +G D+ T+++V P
Sbjct: 304 VVKELVVSAGKSVQITLPKNEVQLNAFVLPEAEPGETYTYDWQLITHPTDY-SGEVERKHSQSLQLSKLTPGLYEFKVTVDGQNAHGEGYVNVTVKPEPRKNRPPVAVVSPQFQEISLPTTSTIIDGSQSTDDDKIVQYHWEELKGPLREEKI-SEDTAILKLSK-LVPGNYTFSLTVVDSDGATNSTTASLTVNKAVDYPPVANAGPNQVITLPQNSITLFGNQSTDDHGITSYEWSLSPSSKGKVVEMQGVRTPALQLSAMQEGDYTYQLTVTDTAGQQATAQVTVIVQPENNKPPQADAG--PDKELT--LPVDSTTLDGSKSTDDQRVVSYLWEQSRGPDGVQLENANSSVATVTGLQVGTYVFTLTVKDERNLQSQSSVNVIVKEEINKPPVAKIA-GNVVVTLPTSTAELDGSRSSDDKGIVSYLWTRDETSPAAGEVLNHSDHHPVLFLSNLVEGTYTFHLKVTDAKGESDTDRTTVEVKP 783
BLAST of Dyslexia-associated protein KIAA0319-like protein vs. Ensembl Mouse
Match: AU040320 (expressed sequence AU040320 [Source:MGI Symbol;Acc:MGI:2140475]) HSP 1 Score: 302.368 bits (773), Expect = 3.838e-91 Identity = 195/488 (39.96%), Postives = 269/488 (55.12%), Query Frame = 3
Query: 240 VTKRLKVNIGKNITIFLPKNSVSLVANV--SGNPNQKYDYEWDLVSKPSDQNAGNLEGKNNRELILKNLILGEYQFKLMVKGNNSYGEALVFVFVKP-------------------------------GSTDDDKIVSYHWEIIQGPIVKENIMKDDQPMLQLDKTITQGNYTFKLTVKDTSGQLNFTIANLIVLPEKDYPPKSDPGPNMILNLPVNSAILNGSGSTDDKKIVSYEW--SKVSDGLTADIQGVREPILKLSNLQEGTYTFNLKVTDSADQVSNKEVKVYVKPRVNVPPVAKASTTPDGIVTVRLPATEAVLNGSLSSDDDKIVKYQWEQTSGQQKLNIVDGDKPIAFVNDLKIGSFQFRLTVWDSDKQAGSDIVTLKVNENQNQKPKATVVESSEVYYLQPDLIKIDGSKSWDDHKIVKYQWIREDDSLAVGDILEKSYSESVXXXXXXXXXXYKFKLIVYDEEGLYDSAITSLQVFP 1598
V K L V+ GK++ I LPKN V L A V P + Y Y+W L++ P+D +G +E K+++ L L L G Y+FK+ V G N++GE V V VKP STDDDKIV YHWE ++GP+ +E I +D +L+L K + GNYTF LTV D+ G N T A+L V DYPP ++ GPN ++ LP NS L G+ STDD I SYEW S S G ++QGVR P L+LS +QEG YT+ L VTD+A Q + +V V V+P N PP A A PD +T LP L+GS S+DD ++V Y WEQ+ G + + + + +A V L++G++ F LTV D V + V E N+ P A + + V L ++DGS+S DD IV Y W R++ S A G++L S VL L+ L+ G Y F L V D +G D+ T+++V P
Sbjct: 304 VVKELVVSAGKSVQITLPKNEVQLNAFVLPEAEPGETYTYDWQLITHPTDY-SGEVERKHSQSLQLSKLTPGLYEFKVTVDGQNAHGEGYVNVTVKPEPRKNRPPVAVVSPQFQEISLPTTSTIIDGSQSTDDDKIVQYHWEELKGPLREEKI-SEDTAILKLSK-LVPGNYTFSLTVVDSDGATNSTTASLTVNKAVDYPPVANAGPNQVITLPQNSITLFGNQSTDDHGITSYEWSLSPSSKGKVVEMQGVRTPALQLSAMQEGDYTYQLTVTDTAGQQATAQVTVIVQPENNKPPQADAG--PDKELT--LPVDSTTLDGSKSTDDQRVVSYLWEQSRGPDGVQLENANSSVATVTGLQVGTYVFTLTVKDERNLQSQSSVNVIVKEEINKPPVAKIA-GNVVVTLPTSTAELDGSRSSDDKGIVSYLWTRDETSPAAGEVLNHSDHHPVLFLSNLVEGTYTFHLKVTDAKGESDTDRTTVEVKP 783
BLAST of Dyslexia-associated protein KIAA0319-like protein vs. Ensembl Mouse
Match: D130043K22Rik (RIKEN cDNA D130043K22 gene [Source:MGI Symbol;Acc:MGI:3036268]) HSP 1 Score: 290.812 bits (743), Expect = 6.710e-87 Identity = 187/486 (38.48%), Postives = 254/486 (52.26%), Query Frame = 3
Query: 246 KRLKVNIGKNITIFLPKNSVSLVANVSGNP--NQKYDYEWDLVSKPSDQNAGNLEGKNNRELILKNLILGEYQFKLMVKGNNSYGEALVFVFVKPG-------------------------------STDDDKIVSYHWEIIQGPIVKENIMKDDQPMLQLDKTITQGNYTFKLTVKDTSGQLNFTIANLIVLPEKDYPPKSDPGPNMILNLPVNSAILNGSGSTDDKKIVSYEWSKVSDGLTAD--IQGVREPILKLSNLQEGTYTFNLKVTDSADQVSNKEVKVYVKPRVNVPPVAKASTTPDGIVTVRLPATEAVLNGSLSSDDDKIVKYQWEQTSGQQKLNIVDGDKPIAFVNDLKIGSFQFRLTVWDSDKQAGSDIVTLKVNENQNQKPKATVVESSEVYYLQPDLIKIDGSKSWDDHKIVKYQWIREDDSLAVGDILEKSYSESVXXXXXXXXXXYKFKLIVYDEEGLYDSAITSLQVFP 1598
K L V+ G N+ + LP L A+V P + Y YEW L+S P D G ++ +N L L L +G Y F++ V N++GE V V V P STDD +IVSYHWE + GP + E D P+L+L + GNYTF+LT+ D+ G N T A+L++ DYPP ++ GPN + LP N+ ILNG+ S+DD +IV YEW G + + +QG + P L LS LQEG YTF L VTDS+ Q S V V V+ N PVA A PD + P A L+GS SSDD IV Y WE G + + + DK IA V L++G + FRLTV D + + +T+ V + N P+A V L + I +DGS+S DD IV Y WIR+ S A GD++ S + L LT L+ G+Y F L+V D +G DS +++V P
Sbjct: 342 KALAVSAGDNLVLTLPDREAELKASVEPAPPADTTYSYEWSLMSHPVDFQ-GKIKQENKPTLHLSQLSVGLYAFRVAVSSENAFGEGYVNVTVMPAARVNQPPVAVVSPQTQELSVPLTSALIDGSQSTDDTEIVSYHWEEVDGPFLGEEF-PADTPILRLSNLVP-GNYTFRLTITDSDGATNSTTASLVIRDAVDYPPVANAGPNQTITLPQNTIILNGNQSSDDHQIVLYEWFAGPGGESKEMVMQGAQTPYLHLSELQEGEYTFQLMVTDSSGQQSTALVAVTVQAENNQAPVAVAG--PDKELV--FPVQSATLDGSRSSDDHGIVCYHWEHIRGPSAVEMENVDKAIATVTGLQVGIYHFRLTVRDQQGLSSTSTLTVAVKKENNSPPRAQ-AGGRHVLILPNNSITLDGSRSTDDRGIVSYLWIRDGQSPAAGDVIGGSDHRAALQLTNLVEGVYTFHLLVTDSQGASDSDAATVEVLP 819
BLAST of Dyslexia-associated protein KIAA0319-like protein vs. Ensembl Mouse
Match: D130043K22Rik (RIKEN cDNA D130043K22 gene [Source:MGI Symbol;Acc:MGI:3036268]) HSP 1 Score: 269.626 bits (688), Expect = 5.909e-81 Identity = 170/440 (38.64%), Postives = 227/440 (51.59%), Query Frame = 3
Query: 246 KRLKVNIGKNITIFLPKNSVSLVANVSGNP--NQKYDYEWDLVSKPSDQNAGNLEGKNNRELILKNLILGEYQFKLMVKGNNSYGEALVFVFVKPG-------------------------------STDDDKIVSYHWEIIQGPIVKENIMKDDQPMLQLDKTITQGNYTFKLTVKDTSGQLNFTIANLIVLPEKDYPPKSDPGPNMILNLPVNSAILNGSGSTDDKKIVSYEWSKVSDGLTAD--IQGVREPILKLSNLQEGTYTFNLKVTDSADQVSNKEVKVYVKPRVNVPPVAKASTTPDGIVTVRLPATEAVLNGSLSSDDDKIVKYQWEQTSGQQKLNIVDGDKPIAFVNDLKIGSFQFRLTVWDSDKQAGSDIVTLKVNENQNQKPKATVVESSEVYYLQPDLIKIDGSKSWDDHKIVKYQWIREDDSLAVG 1460
K L V+ G N+ + LP L A+V P + Y YEW L+S P D G ++ +N L L L +G Y F++ V N++GE V V V P STDD +IVSYHWE + GP + E D P+L+L + GNYTF+LT+ D+ G N T A+L++ DYPP ++ GPN + LP N+ ILNG+ S+DD +IV YEW G + + +QG + P L LS LQEG YTF L VTDS+ Q S V V V+ N PVA A PD + P A L+GS SSDD IV Y WE G + + + DK IA V L++G + FRLTV D + + +T+ V + N P+A V L + I +DGS+S DD IV Y WIR+ S A G
Sbjct: 342 KALAVSAGDNLVLTLPDREAELKASVEPAPPADTTYSYEWSLMSHPVDFQ-GKIKQENKPTLHLSQLSVGLYAFRVAVSSENAFGEGYVNVTVMPAARVNQPPVAVVSPQTQELSVPLTSALIDGSQSTDDTEIVSYHWEEVDGPFLGEEF-PADTPILRLSN-LVPGNYTFRLTITDSDGATNSTTASLVIRDAVDYPPVANAGPNQTITLPQNTIILNGNQSSDDHQIVLYEWFAGPGGESKEMVMQGAQTPYLHLSELQEGEYTFQLMVTDSSGQQSTALVAVTVQAENNQAPVAVAG--PDKELV--FPVQSATLDGSRSSDDHGIVCYHWEHIRGPSAVEMENVDKAIATVTGLQVGIYHFRLTVRDQQGLSSTSTLTVAVKKENNSPPRAQ-AGGRHVLILPNNSITLDGSRSTDDRGIVSYLWIRDGQSPAAG 773 HSP 2 Score: 161.384 bits (407), Expect = 8.014e-42 Identity = 120/375 (32.00%), Postives = 197/375 (52.53%), Query Frame = 3
Query: 495 EALVFVFVKPGSTDDDKIVSYHWEIIQGPI-VKENIMKDDQPMLQLDKTITQGNYTFKLTVKDTSGQLNFTIANLIVLPEK--DYPPKSDPGPNMI-LNLPVNSAILNGSGSTDDKKIVSYEWSKVSDGLTADIQGVREPILKLSNLQEGTYTFNLKVTDSADQVSNKEVKVYVKPRVNVPPVAKASTTPDGIVTVRLPATEAVLNGSLSSDDDKIVKYQW-EQTSGQQKLNIVDGDK-PIAFVNDLKIGSFQFRLTVWDSDKQAGSDIVTLKVNENQNQKPKATVVESSE-VYYLQPDLIKIDGSKSWDDHKIVKYQW--IREDDSLAVGDILEKSYSESVXXXXXXXXXXYKFKLIVYDEEGLYDSAITSLQV 1592
EA + V+P + D SY W ++ P+ + I ++++P L L + ++ G Y F++ V + N+ V+P + PP + P L++P+ SA+++GS STDD +IVSY W +V + PIL+LSNL G YTF L +TDS ++ + ++ V+ PPVA A T+ LP +LNG+ SSDD +IV Y+W G+ K ++ G + P +++L+ G + F+L V DS Q + +V + V NQ P A E V+ +Q +DGS+S DDH IV Y W IR ++ + ++ +++ +TGL G+Y F+L V D++GL ++ ++ V
Sbjct: 360 EAELKASVEP-APPADTTYSYEWSLMSHPVDFQGKIKQENKPTLHLSQ-LSVGLYAFRVAVS-SENAFGEGYVNVTVMPAARVNQPPVAVVSPQTQELSVPLTSALIDGSQSTDDTEIVSYHWEEVDGPFLGEEFPADTPILRLSNLVPGNYTFRLTITDSDGATNSTTASLVIRDAVDYPPVANAGPN----QTITLPQNTIILNGNQSSDDHQIVLYEWFAGPGGESKEMVMQGAQTPYLHLSELQEGEYTFQLMVTDSSGQQSTALVAVTVQAENNQAPVAVAGPDKELVFPVQ--SATLDGSRSSDDHGIVCYHWEHIRGPSAVEMENV-----DKAIATVTGLQVGIYHFRLTVRDQQGLSSTSTLTVAV 720
BLAST of Dyslexia-associated protein KIAA0319-like protein vs. UniProt/SwissProt
Match: sp|Q5VV43|K0319_HUMAN (Dyslexia-associated protein KIAA0319 OS=Homo sapiens OX=9606 GN=KIAA0319 PE=1 SV=1) HSP 1 Score: 305.834 bits (782), Expect = 1.292e-91 Identity = 198/486 (40.74%), Postives = 264/486 (54.32%), Query Frame = 3
Query: 246 KRLKVNIGKNITIFLPKNSVSLVANVSGNP--NQKYDYEWDLVSKPSDQNAGNLEGKNNRELILKNLILGEYQFKLMVKGNNSYGEALVFVFVKPG-------------------------------STDDDKIVSYHWEIIQGPIVKENIMKDDQPMLQLDKTITQGNYTFKLTVKDTSGQLNFTIANLIVLPEKDYPPKSDPGPNMILNLPVNSAILNGSGSTDDKKIVSYEWS--KVSDGLTADIQGVREPILKLSNLQEGTYTFNLKVTDSADQVSNKEVKVYVKPRVNVPPVAKASTTPDGIVTVRLPATEAVLNGSLSSDDDKIVKYQWEQTSGQQKLNIVDGDKPIAFVNDLKIGSFQFRLTVWDSDKQAGSDIVTLKVNENQNQKPKATVVESSEVYYLQPDLIKIDGSKSWDDHKIVKYQWIREDDSLAVGDILEKSYSESVXXXXXXXXXXYKFKLIVYDEEGLYDSAITSLQVFP 1598
K L V+ G N+ I LP N V L A V+ P Y+YEW+L+S P+D G ++ + + L L L +G Y FK+ V N++GE V V VKP STDD +IVSYHWE I GP ++E D P+L+L + GNY+F+LTV D+ G N T A LIV DYPP ++ GPN + LP NS LNG+ S+DD +IV YEWS S+G +QGV+ P L LS +QEG YTF LKVTDS+ Q S V V V+P N PPVA A PD + P A L+GS SSDD IV Y WE G + + + DK IA V L++G++ FRLTV D + + +T+ V + N P+A V L + I +DGS+S DD +IV Y WIR+ S A GD+++ S L LT L+ G+Y F L V D +G D+ +++V P
Sbjct: 333 KELTVSAGDNLIITLPDNEVELKAFVAPAPPVETTYNYEWNLISHPTDYQ-GEIKQGHKQTLNLSQLSVGLYVFKVTVSSENAFGEGFVNVTVKPARRVNLPPVAVVSPQLQELTLPLTSALIDGSQSTDDTEIVSYHWEEINGPFIEEKT-SVDSPVLRLSN-LDPGNYSFRLTVTDSDGATNSTTAALIVNNAVDYPPVANAGPNHTITLPQNSITLNGNQSSDDHQIVLYEWSLGPGSEGKHVVMQGVQTPYLHLSAMQEGDYTFQLKVTDSSRQQSTAVVTVIVQPENNRPPVAVAG--PDKELI--FPVESATLDGSSSSDDHGIVFYHWEHVRGPSAVEMENIDKAIATVTGLQVGTYHFRLTVKDQQGLSSTSTLTVAVKKENNSPPRAR-AGGRHVLVLPNNSITLDGSRSTDDQRIVSYLWIRDGQSPAAGDVIDGSDHSVALQLTNLVEGVYTFHLRVTDSQGASDTDTATVEVQP 810
BLAST of Dyslexia-associated protein KIAA0319-like protein vs. UniProt/SwissProt
Match: sp|Q8K135|K319L_MOUSE (Dyslexia-associated protein KIAA0319-like protein OS=Mus musculus OX=10090 GN=Kiaa0319l PE=1 SV=1) HSP 1 Score: 302.368 bits (773), Expect = 1.716e-90 Identity = 195/488 (39.96%), Postives = 269/488 (55.12%), Query Frame = 3
Query: 240 VTKRLKVNIGKNITIFLPKNSVSLVANV--SGNPNQKYDYEWDLVSKPSDQNAGNLEGKNNRELILKNLILGEYQFKLMVKGNNSYGEALVFVFVKP-------------------------------GSTDDDKIVSYHWEIIQGPIVKENIMKDDQPMLQLDKTITQGNYTFKLTVKDTSGQLNFTIANLIVLPEKDYPPKSDPGPNMILNLPVNSAILNGSGSTDDKKIVSYEW--SKVSDGLTADIQGVREPILKLSNLQEGTYTFNLKVTDSADQVSNKEVKVYVKPRVNVPPVAKASTTPDGIVTVRLPATEAVLNGSLSSDDDKIVKYQWEQTSGQQKLNIVDGDKPIAFVNDLKIGSFQFRLTVWDSDKQAGSDIVTLKVNENQNQKPKATVVESSEVYYLQPDLIKIDGSKSWDDHKIVKYQWIREDDSLAVGDILEKSYSESVXXXXXXXXXXYKFKLIVYDEEGLYDSAITSLQVFP 1598
V K L V+ GK++ I LPKN V L A V P + Y Y+W L++ P+D +G +E K+++ L L L G Y+FK+ V G N++GE V V VKP STDDDKIV YHWE ++GP+ +E I +D +L+L K + GNYTF LTV D+ G N T A+L V DYPP ++ GPN ++ LP NS L G+ STDD I SYEW S S G ++QGVR P L+LS +QEG YT+ L VTD+A Q + +V V V+P N PP A A PD +T LP L+GS S+DD ++V Y WEQ+ G + + + + +A V L++G++ F LTV D V + V E N+ P A + + V L ++DGS+S DD IV Y W R++ S A G++L S VL L+ L+ G Y F L V D +G D+ T+++V P
Sbjct: 304 VVKELVVSAGKSVQITLPKNEVQLNAFVLPEAEPGETYTYDWQLITHPTDY-SGEVERKHSQSLQLSKLTPGLYEFKVTVDGQNAHGEGYVNVTVKPEPRKNRPPVAVVSPQFQEISLPTTSTIIDGSQSTDDDKIVQYHWEELKGPLREEKI-SEDTAILKLSK-LVPGNYTFSLTVVDSDGATNSTTASLTVNKAVDYPPVANAGPNQVITLPQNSITLFGNQSTDDHGITSYEWSLSPSSKGKVVEMQGVRTPALQLSAMQEGDYTYQLTVTDTAGQQATAQVTVIVQPENNKPPQADAG--PDKELT--LPVDSTTLDGSKSTDDQRVVSYLWEQSRGPDGVQLENANSSVATVTGLQVGTYVFTLTVKDERNLQSQSSVNVIVKEEINKPPVAKIA-GNVVVTLPTSTAELDGSRSSDDKGIVSYLWTRDETSPAAGEVLNHSDHHPVLFLSNLVEGTYTFHLKVTDAKGESDTDRTTVEVKP 783
BLAST of Dyslexia-associated protein KIAA0319-like protein vs. UniProt/SwissProt
Match: sp|Q5RFR6|K319L_PONAB (Dyslexia-associated protein KIAA0319-like protein OS=Pongo abelii OX=9601 GN=Kiaa0319l PE=2 SV=1) HSP 1 Score: 301.982 bits (772), Expect = 2.316e-90 Identity = 198/488 (40.57%), Postives = 269/488 (55.12%), Query Frame = 3
Query: 240 VTKRLKVNIGKNITIFLPKNSVSLVANVSGNP--NQKYDYEWDLVSKPSDQNAGNLEGKNNRELILKNLILGEYQFKLMVKGNNSYGEALVFVFVKP-------------------------------GSTDDDKIVSYHWEIIQGPIVKENIMKDDQPMLQLDKTITQGNYTFKLTVKDTSGQLNFTIANLIVLPEKDYPPKSDPGPNMILNLPVNSAILNGSGSTDDKKIVSYEW--SKVSDGLTADIQGVREPILKLSNLQEGTYTFNLKVTDSADQVSNKEVKVYVKPRVNVPPVAKASTTPDGIVTVRLPATEAVLNGSLSSDDDKIVKYQWEQTSGQQKLNIVDGDKPIAFVNDLKIGSFQFRLTVWDSDKQAGSDIVTLKVNENQNQKPKATVVESSEVYYLQPDLIKIDGSKSWDDHKIVKYQWIREDDSLAVGDILEKSYSESVXXXXXXXXXXYKFKLIVYDEEGLYDSAITSLQVFP 1598
V K L V+ G ++ I LPKN V L A V P + Y Y+W L++ P D +G +EGK+++ L L L G Y+FK++V+G N++GE V V VKP STDDDKIV YHWE ++GP+ +E I +D +L+L K + GNYTF LTV D+ G N T ANL V DYPP ++ GPN ++ LP NS L G+ STDD I SYEW S S G ++QGVR P L+LS +QEG YT+ L VTD+ Q + +V V V+P N PP A A PD +T LP L+GS SSDD KI+ Y WE+T G + + + + IA V L++G++ F LTV D V + V E N+ P A + + V L ++DGSKS DD IV Y W R++ S A G++L S +L L+ L+ G Y F L V D +G D+ T+++V P
Sbjct: 305 VIKELVVSAGDSVQITLPKNEVQLNAYVLQEPPKGETYTYDWQLITHPRDY-SGEMEGKHSQILKLSKLTPGLYEFKVIVEGQNAHGEGYVNVTVKPEPRKNRPPIAIVSPQFQEISLPTTSTVIDGSQSTDDDKIVQYHWEELKGPLREEKI-SEDTAILKLSKLVP-GNYTFSLTVVDSDGATNSTTANLTVNKAVDYPPVANAGPNQVITLPQNSITLFGNQSTDDHGITSYEWSLSPSSKGKVVEMQGVRTPTLQLSAMQEGDYTYQLTVTDTIGQQATAQVTVIVQPENNKPPQADAG--PDKELT--LPVDSTTLDGSKSSDDQKIISYLWEKTQGPDGVQLENANSSIATVTGLQVGTYVFTLTVKDERNLQSQSSVNVIVKEEINKPPIAKIT-GNVVITLPTSTAELDGSKSSDDKGIVSYLWTRDEGSPAAGEVLNHSDHHPILFLSNLVEGTYTFHLKVTDAKGESDTDRTTVEVKP 784
BLAST of Dyslexia-associated protein KIAA0319-like protein vs. UniProt/SwissProt
Match: sp|Q8IZA0|K319L_HUMAN (Dyslexia-associated protein KIAA0319-like protein OS=Homo sapiens OX=9606 GN=KIAA0319L PE=1 SV=2) HSP 1 Score: 301.982 bits (772), Expect = 2.841e-90 Identity = 197/488 (40.37%), Postives = 270/488 (55.33%), Query Frame = 3
Query: 240 VTKRLKVNIGKNITIFLPKNSVSLVANVSGNP--NQKYDYEWDLVSKPSDQNAGNLEGKNNRELILKNLILGEYQFKLMVKGNNSYGEALVFVFVKP-------------------------------GSTDDDKIVSYHWEIIQGPIVKENIMKDDQPMLQLDKTITQGNYTFKLTVKDTSGQLNFTIANLIVLPEKDYPPKSDPGPNMILNLPVNSAILNGSGSTDDKKIVSYEW--SKVSDGLTADIQGVREPILKLSNLQEGTYTFNLKVTDSADQVSNKEVKVYVKPRVNVPPVAKASTTPDGIVTVRLPATEAVLNGSLSSDDDKIVKYQWEQTSGQQKLNIVDGDKPIAFVNDLKIGSFQFRLTVWDSDKQAGSDIVTLKVNENQNQKPKATVVESSEVYYLQPDLIKIDGSKSWDDHKIVKYQWIREDDSLAVGDILEKSYSESVXXXXXXXXXXYKFKLIVYDEEGLYDSAITSLQVFP 1598
V K L V+ G+++ I LPKN V L A V P + Y Y+W L++ P D +G +EGK+++ L L L G Y+FK++V+G N++GE V V VKP STDDDKIV YHWE ++GP+ +E I +D +L+L K + GNYTF LTV D+ G N T ANL V DYPP ++ GPN ++ LP NS L G+ STDD I SYEW S S G ++QGVR P L+LS +QEG YT+ L VTD+ Q + +V V V+P N PP A A PD +T LP L+GS SSDD KI+ Y WE+T G + + + + +A V L++G++ F LTV D V + V E N+ P A + + V L ++DGSKS DD IV Y W R++ S A G++L S +L L+ L+ G Y F L V D +G D+ T+++V P
Sbjct: 305 VIKELVVSAGESVQITLPKNEVQLNAYVLQEPPKGETYTYDWQLITHPRDY-SGEMEGKHSQILKLSKLTPGLYEFKVIVEGQNAHGEGYVNVTVKPEPRKNRPPIAIVSPQFQEISLPTTSTVIDGSQSTDDDKIVQYHWEELKGPLREEKI-SEDTAILKLSKLVP-GNYTFSLTVVDSDGATNSTTANLTVNKAVDYPPVANAGPNQVITLPQNSITLFGNQSTDDHGITSYEWSLSPSSKGKVVEMQGVRTPTLQLSAMQEGDYTYQLTVTDTIGQQATAQVTVIVQPENNKPPQADAG--PDKELT--LPVDSTTLDGSKSSDDQKIISYLWEKTQGPDGVQLENANSSVATVTGLQVGTYVFTLTVKDERNLQSQSSVNVIVKEEINKPPIAKIT-GNVVITLPTSTAELDGSKSSDDKGIVSYLWTRDEGSPAAGEVLNHSDHHPILFLSNLVEGTYTFHLKVTDAKGESDTDRTTVEVKP 784
BLAST of Dyslexia-associated protein KIAA0319-like protein vs. UniProt/SwissProt
Match: sp|P0CI71|K0319_RAT (Dyslexia-associated protein KIAA0319 homolog OS=Rattus norvegicus OX=10116 PE=2 SV=1) HSP 1 Score: 296.204 bits (757), Expect = 4.977e-88 Identity = 190/486 (39.09%), Postives = 259/486 (53.29%), Query Frame = 3
Query: 246 KRLKVNIGKNITIFLPKNSVSLVANVSGNP--NQKYDYEWDLVSKPSDQNAGNLEGKNNRELILKNLILGEYQFKLMVKGNNSYGEALVFVFVKPG-------------------------------STDDDKIVSYHWEIIQGPIVKENIMKDDQPMLQLDKTITQGNYTFKLTVKDTSGQLNFTIANLIVLPEKDYPPKSDPGPNMILNLPVNSAILNGSGSTDDKKIVSYEWSKVSDGLTAD--IQGVREPILKLSNLQEGTYTFNLKVTDSADQVSNKEVKVYVKPRVNVPPVAKASTTPDGIVTVRLPATEAVLNGSLSSDDDKIVKYQWEQTSGQQKLNIVDGDKPIAFVNDLKIGSFQFRLTVWDSDKQAGSDIVTLKVNENQNQKPKATVVESSEVYYLQPDLIKIDGSKSWDDHKIVKYQWIREDDSLAVGDILEKSYSESVXXXXXXXXXXYKFKLIVYDEEGLYDSAITSLQVFP 1598
K L V+ G N+ + LP L A+V P + Y YEW L+S P D G ++ +N L L L +G Y F++ V G N++GE V V V P STDD +IVSYHWE + GP + E + DD P+L+L + GNYTF+LT+ D+ G N T A LI+ DYPP ++ GPN + LP N+ ILNG+ S+DD +IV YEW G + + +QG + P L LS LQEG YTF L VTDS+ Q S V + V+ N PVA A PD + P A+L+GS SSDD IV Y+WE G + + + DK IA V L++G++ FRLTV D + + +T+ V + N P+A V L + I +DGS+S DD IV Y WIR+ S A GDI+ S + + L LT L+ G+Y F L+V D +G DS ++V P
Sbjct: 342 KALAVSAGDNLVLTLPNGEAELKASVEPAPPADTAYTYEWSLMSHPVDFQ-GKIKQENKPTLHLSQLSVGLYAFRVAVSGENAFGEGYVNVTVMPAARINQPPVAIVSPQIQELSLPLTSALIDGSQSTDDAEIVSYHWEEVDGPFLGEAFL-DDSPLLRLSN-LDPGNYTFRLTITDSDGATNSTTAALIIRGSLDYPPVANAGPNQTITLPQNTIILNGNQSSDDHQIVLYEWFPDPGGESKEMVMQGAQTPYLHLSELQEGEYTFQLMVTDSSGQQSTALVTLTVQAENNQAPVAVAG--PDKELV--FPVQSAMLDGSRSSDDHGIVCYRWEHIRGPSAVEMENVDKAIATVTGLQVGTYHFRLTVRDQQGLSSTSTLTVAVKKENNSPPRAQ-AGGRHVLMLPNNSITLDGSRSTDDRGIVSYLWIRDGQSPAAGDIIGSSDNGAALQLTNLVEGVYTFHLLVTDSQGASDSDTAIVEVLP 819
BLAST of Dyslexia-associated protein KIAA0319-like protein vs. TrEMBL
Match: A0A3M0LAG6 (Uncharacterized protein OS=Hirundo rustica rustica OX=333673 GN=DUI87_08462 PE=4 SV=1) HSP 1 Score: 335.109 bits (858), Expect = 1.038e-100 Identity = 203/455 (44.62%), Postives = 269/455 (59.12%), Query Frame = 3
Query: 246 KRLKVNIGKNITIFLPKNSVSLVANVSGNPNQK--YDYEWDLVSKPSDQNAGNLEGKNNRELILKNLILGEYQFKLMVKGNNSYGEALVFVFVKPGSTDDDKIVSYHWEIIQGPIVKENIMKDDQPMLQLDKTITQGNYTFKLTVKDTSGQLNFTIANLIVLPEKDYPPKSDPGPNMILNLPVNSAILNGSGSTDDKKIVSYEW--SKVSDGLTADIQGVREPILKLSNLQEGTYTFNLKVTDSADQVSNKEVKVYVKPRVNVPPVAKASTTPDGIVTVRLPATEAVLNGSLSSDDDKIVKYQWEQTSGQQKLNIVDGDKPIAFVNDLKIGSFQFRLTVWDSDKQAGSDIVTLKVNENQNQKPKATVVESSEVYYLQPDLIKIDGSKSWDDHKIVKYQWIREDDSLAVGDILEKSYSESVXXXXXXXXXXYKFKLIVYDEEGLYDSAITSLQVFP 1598
K L V++G NI + LPKN V L A P+ + Y YEW L+S P+D +G +E ++++ L L +L +G Y FK+ V G N++GE V V VKP S DD KIVSYHWE I+GP+ +E D P+L L + GNYTF+LTV D+ G N TIA+L V DYPP ++ GPN + LP N LNG+ S+DD +IVSYEW S S G +QGVR P L+LS +QEG YTF L VTDSA Q S EV + V+P N PPVA A PD +T P L+GS S DD IV Y WE SG + + + DK IA V+ L++G++ FRLTV D + + ++++ V E N P+A V L + + +DGS S DD IV Y WIR+ S A GD++ S E+VL LT L+ G Y F L V D +G D +++V P
Sbjct: 335 KELTVSVGDNIQVILPKNEVELNAFAIPPPSTETAYTYEWSLISHPADY-SGEMEHRHSQTLKLSHLSVGLYAFKVTVSGENAFGEGFVNVTVKPESLDDAKIVSYHWEEIKGPL-REQKASADTPVLHLSNLVP-GNYTFRLTVIDSDGAANSTIASLTVNKPVDYPPIANAGPNQAVTLPQNFITLNGNQSSDDHEIVSYEWSLSPRSKGKVVAMQGVRTPYLQLSAMQEGDYTFQLTVTDSARQRSTAEVTLIVQPENNSPPVAVAG--PDKELT--FPVESTTLDGSKSQDDQGIVFYHWENISGPSSVQMENDDKAIATVSGLQVGTYHFRLTVKDQQGLSSASVLSITVKEENNSPPRAH-AGGKHVLVLPNNSVTLDGSGSADDQGIVSYLWIRDGQSPAAGDVIHGSDHEAVLQLTNLVEGTYIFHLKVTDTKGDSDVDSATVEVRP 781
BLAST of Dyslexia-associated protein KIAA0319-like protein vs. TrEMBL
Match: V4B545 (Uncharacterized protein OS=Lottia gigantea OX=225164 GN=LOTGIDRAFT_138056 PE=4 SV=1) HSP 1 Score: 327.405 bits (838), Expect = 2.643e-100 Identity = 206/484 (42.56%), Postives = 282/484 (58.26%), Query Frame = 3
Query: 246 KRLKVNIGKNITIFLPKNSVSLVANVSGNPN--QKYDYEWDLVSKPS-DQNAGNLEGKNNRELILKNLILGEYQFKLMVKGNNSYGEALVFVFVKP------------------------------GSTDDDKIVSYHWEIIQGPIVKENIMKDDQPMLQLDKTITQGNYTFKLTVKDTSGQLNFTIANLIVLPEKDYPPKSDPGPNMILNLPVNSAILNGSGSTDDKKIVSYEWSKVSDG-LTADIQGVREPILKLSNLQEGTYTFNLKVTDSADQVSNKEVKVYVKPRVNVPPVAKASTTPDGIVTVRLPATEAVLNGSLSSDDDKIVKYQWEQTSGQQKLNIVDGDKPIAFVN-DLKIGSFQFRLTVWDSDKQAGSDIVTLKVNENQNQKPKATVVESSEVYYLQPDLIKIDGSKSWDDHKIVKYQWIREDDSLAVGDILEKSYSESVXXXXXXXXXXYKFKLIVYDEEGLYDSAITSLQV 1592
K L V+ GK I LP N V+L A V P+ + Y Y W +VS P+ D++ G +EGK + LKNLI G Y FK+ V G+N +GE+ V V V P STDDDKIV YHWE + GP+ +E+ + D ML+L + ++ GNYTFKLTV D+ G +N + AN+ V E DYPPK++ G +++++LPV S IL G+ STDDK IVSYEW+K D +T D+ GVR P L L +L+ G YT+ LKVTD++ Q S+ +V V+VKP N PP A + + V LPA VL+G+ SSDD KI+ + W Q SG +L +++ D+ +A LK G + F+L V D+D Q G+ ++T+ ++ N P A +V YL + DGS S DDH IVKY+W R+ SLA GDI+ S S +VL L L+ G Y F L V D EGL +S S+ V
Sbjct: 39 KPLTVSAGKGRIIQLPVNDVALSAFVVQEPDKGETYHYTWSMVSSPNGDKDKGLMEGKTLDTVKLKNLIAGGYIFKVTVTGDNKFGESTVNVTVLPPARMNTSPVAIIKPTNQVIKLPNSGVLDGSDSTDDDKIVKYHWEEVNGPL-QEHSISGDSSMLKL-QNLSPGNYTFKLTVTDSDGAVNSSQANVTVHKETDYPPKANAGSDVVIHLPVKSVILYGNASTDDKGIVSYEWTKTGDTDITNDVSGVRTPFLHLKDLEVGDYTYTLKVTDASGQSSSADVHVFVKPETNQPPKAVTEKS----IEVVLPADNIVLDGTNSSDDSKIITFAWSQKSGPSQLELMNSDRMVAAARGKLKEGIYTFQLLVKDADGQTGTQLLTVTTKKHANLAPVAN-AGGDKVVYLPVSSLVFDGSNSKDDHGIVKYKWSRDQRSLAAGDIVNGSASHAVLQLINLVAGRYIFTLTVVDVEGLSNSDSASVIV 515
BLAST of Dyslexia-associated protein KIAA0319-like protein vs. TrEMBL
Match: A0A226PHE5 (Uncharacterized protein OS=Colinus virginianus OX=9014 GN=H355_005994 PE=4 SV=1) HSP 1 Score: 332.798 bits (852), Expect = 9.998e-100 Identity = 205/456 (44.96%), Postives = 270/456 (59.21%), Query Frame = 3
Query: 246 KRLKVNIGKNITIFLPKNSVSLVANVSGNP--NQKYDYEWDLVSKPSDQNAGNLEGKNNRELILKNLILGEYQFKLMVKGNNSYGEALVFVFVKPGSTDDDKIVSYHWEIIQGPIVKENIMKDDQPMLQLDKTITQGNYTFKLTVKDTSGQLNFTIANLIVLPEKDYPPKSDPGPNMILNLPVNSAILNGSGSTDDKKIVSYEWS---KVSDGLTADIQGVREPILKLSNLQEGTYTFNLKVTDSADQVSNKEVKVYVKPRVNVPPVAKASTTPDGIVTVRLPATEAVLNGSLSSDDDKIVKYQWEQTSGQQKLNIVDGDKPIAFVNDLKIGSFQFRLTVWDSDKQAGSDIVTLKVNENQNQKPKATVVESSEVYYLQPDLIKIDGSKSWDDHKIVKYQWIREDDSLAVGDILEKSYSESVXXXXXXXXXXYKFKLIVYDEEGLYDSAITSLQVFP 1598
K L V+ G NI + LPKN V L A V P Y+YEW L+S P+D G +E + R L L +L +G Y F++ V G N++GE V V VKP STDD KIVSYHWE I+GP+ +E D P+L L + GNYTF+LTV D+ G N T A+L V DYPP ++ GPN + LP N LNG+ S+DD +IVSYEWS + D + A +QGVR P L+LS +QEG YTF L VTDSA Q S EV + V+P N PPVA A PD +T P L+GS S DD IV Y WE SG + + +GDK IA V L++G+++FRLTV D + + ++++ V E N P+A V L + + +DGS+S DD IV Y WIR+ S A GD++ S E+VL LT L+ G+Y F L V D +G D +++V P
Sbjct: 315 KELIVSAGDNIQVTLPKNEVELNAFVVPPPPTETSYNYEWRLISHPTDY-GGEMEHRYTRTLKLSHLSVGLYTFQVTVSGENAFGEGFVNVTVKPESTDDMKIVSYHWEEIKGPL-REQKASADTPVLHLSNLVL-GNYTFRLTVIDSDGAANSTFASLSVNKPVDYPPIANAGPNQAVTLPQNFITLNGNQSSDDHEIVSYEWSLSPRSKDKVVA-MQGVRTPYLQLSAVQEGDYTFQLTVTDSARQQSTAEVTLIVQPENNSPPVAVAG--PDRELT--FPVESTTLDGSRSQDDQGIVFYHWENISGPSYVQMENGDKAIATVTGLQVGTYRFRLTVKDQQGLSSACVLSITVKEESNSPPQAH-AGGKHVLVLPNNSVTLDGSRSADDQGIVSYLWIRDGQSPAAGDVIHGSDHEAVLQLTNLVEGIYIFHLKVTDAKGDSDIDSATVEVRP 761
BLAST of Dyslexia-associated protein KIAA0319-like protein vs. TrEMBL
Match: A0A226MGN8 (Uncharacterized protein OS=Callipepla squamata OX=9009 GN=ASZ78_003580 PE=4 SV=1) HSP 1 Score: 330.872 bits (847), Expect = 1.745e-99 Identity = 204/456 (44.74%), Postives = 270/456 (59.21%), Query Frame = 3
Query: 246 KRLKVNIGKNITIFLPKNSVSLVANVSGNPNQK--YDYEWDLVSKPSDQNAGNLEGKNNRELILKNLILGEYQFKLMVKGNNSYGEALVFVFVKPGSTDDDKIVSYHWEIIQGPIVKENIMKDDQPMLQLDKTITQGNYTFKLTVKDTSGQLNFTIANLIVLPEKDYPPKSDPGPNMILNLPVNSAILNGSGSTDDKKIVSYEWS---KVSDGLTADIQGVREPILKLSNLQEGTYTFNLKVTDSADQVSNKEVKVYVKPRVNVPPVAKASTTPDGIVTVRLPATEAVLNGSLSSDDDKIVKYQWEQTSGQQKLNIVDGDKPIAFVNDLKIGSFQFRLTVWDSDKQAGSDIVTLKVNENQNQKPKATVVESSEVYYLQPDLIKIDGSKSWDDHKIVKYQWIREDDSLAVGDILEKSYSESVXXXXXXXXXXYKFKLIVYDEEGLYDSAITSLQVFP 1598
K L V+ G NI + LPKN V L A P + Y+YEW L+S P+D G +E + R L L +L +G Y FK+ V G N++GE V V VKP STDD KIVSYHWE I+GP+ +E D P+L L + GNYTF+LTV D+ G N T A+L V DYPP ++ GPN + LP N LNG+ S+DD +IVSYEWS + D + A +QGVR P L+LS +QEG YTF L VTDSA Q S EV + V+P N PPVA A PD +T P L+GS S DD IV Y WE SG + + +GDK IA V L++G+++FRLTV D + + ++++ V E N P+A V L + + +DGS+S DD IV Y WIR+ S A GD++ S ++VL LT L+ G+Y F L V D +G D +++V P
Sbjct: 315 KELIVSAGDNIQVTLPKNEVELNAFAVPPPATETSYNYEWRLISHPTDY-GGEMEHRYTRTLKLSHLSVGLYAFKVTVSGENAFGEGFVNVTVKPESTDDVKIVSYHWEEIKGPL-REQKASADTPVLHLSNLVL-GNYTFRLTVIDSDGAANSTFASLSVSRPVDYPPIANAGPNQAVTLPQNFITLNGNQSSDDHEIVSYEWSLSPRSKDKVVA-MQGVRTPYLQLSAMQEGDYTFQLTVTDSARQQSTAEVTLIVQPENNSPPVAVAG--PDRELT--FPVESTTLDGSRSQDDQGIVFYHWENISGPSYVQMENGDKAIATVTGLQVGTYRFRLTVKDQQGLSSTCVLSITVKEESNSPPQAH-AGGKHVLVLPNNSVTLDGSRSADDQGIVSYLWIRDGQSPAAGDVIHGSDHDAVLQLTNLVEGIYIFHLKVTDVKGDSDIDSATVEVRP 761
BLAST of Dyslexia-associated protein KIAA0319-like protein vs. TrEMBL
Match: A0A091RLF2 (Dyslexia-associated protein KIAA0319 (Fragment) OS=Mesitornis unicolor OX=54374 GN=N332_07768 PE=4 SV=1) HSP 1 Score: 323.939 bits (829), Expect = 1.521e-97 Identity = 206/487 (42.30%), Postives = 270/487 (55.44%), Query Frame = 3
Query: 243 TKRLKVNIGKNITIFLPKNSVSLVANVSGNP--NQKYDYEWDLVSKPSDQNAGNLEGKNNRELILKNLILGEYQFKLMVKGNNSYGEALVFVFVKPG-------------------------------STDDDKIVSYHWEIIQGPIVKENIMKDDQPMLQLDKTITQGNYTFKLTVKDTSGQLNFTIANLIVLPEKDYPPKSDPGPNMILNLPVNSAILNGSGSTDDKKIVSYEW--SKVSDGLTADIQGVREPILKLSNLQEGTYTFNLKVTDSADQVSNKEVKVYVKPRVNVPPVAKASTTPDGIVTVRLPATEAVLNGSLSSDDDKIVKYQWEQTSGQQKLNIVDGDKPIAFVNDLKIGSFQFRLTVWDSDKQAGSDIVTLKVNENQNQKPKATVVESSEVYYLQPDLIKIDGSKSWDDHKIVKYQWIREDDSLAVGDILEKSYSESVXXXXXXXXXXYKFKLIVYDEEGLYDSAITSLQVFP 1598
TK L V+ G NI + LPKN V L A V P Y YEW+L+S P+D G +E ++++ L L +L +G Y FK+ V G N++GE V V VKP S DD KIVSYHWE I+GP+ +E D P+L L + GNYTF+LTV D+ G N TIA+L V DYPP ++ GPN + LP N LNG+ S+DD +IVSYEW S S G +QGVR P L+LS +QEG YTF L VTDSA Q S EV + V+P N PPVA A PD +T P L+GS S DD IV Y WE SG + + +GDK IA V L++G+++FRLTV D + + ++++ V E N P+A V L + + +DGS+S DD IV Y WIR+ S A GD+++ S E+VL LT L+ G Y F L V D +G D ++V P
Sbjct: 323 TKELLVSAGDNIQVMLPKNEVELNAFVVPPPPTETAYTYEWNLISHPADY-GGEMERRHSQTLKLSHLSVGLYAFKVAVSGENAFGEGFVNVTVKPAVRVNQPPVAVASPKVQEVSLPTTSTFIDGSQSIDDMKIVSYHWEEIKGPL-REQKASADTPVLHLSNLVP-GNYTFRLTVIDSDGAANSTIASLTVSKPVDYPPIANAGPNQAVTLPQNFITLNGNQSSDDHEIVSYEWSLSPKSKGKVVAMQGVRTPYLQLSAMQEGDYTFQLTVTDSARQRSTAEVTLIVQPENNNPPVAVAG--PDKELT--FPVESTTLDGSKSQDDQGIVFYHWENISGPSSIQMENGDKAIATVTGLQVGTYRFRLTVKDQQGLSSASVLSITVKEENNSPPRAH-AGGKHVLVLPNNSVTLDGSRSADDQGIVSYLWIRDGQSPAAGDVIQGSDHEAVLQLTNLVEGTYIFHLKVTDAKGDSDIDSAVVEVRP 801
BLAST of Dyslexia-associated protein KIAA0319-like protein vs. Ensembl Cavefish
Match: si:ch211-193k19.1 (KIAA0319 like [Source:NCBI gene;Acc:103041131]) HSP 1 Score: 288.5 bits (737), Expect = 1.179e-86 Identity = 189/486 (38.89%), Postives = 263/486 (54.12%), Query Frame = 3
Query: 246 KRLKVNIGKNITIFLPKNSVSLVANVSGNP--NQKYDYEWDLVSKPSDQNAGNLEGKNNRELILKNLILGEYQFKLMVKGNNSYGEALVFVFVKP-------------------------------GSTDDDKIVSYHWEIIQGPIVKENIMKDDQPMLQLDKTITQGNYTFKLTVKDTSGQLNFTIANLIVLPEKDYPPKSDPGPNMILNLPVNSAILNGSGSTDDKKIVSYEW--SKVSDGLTADIQGVREPILKLSNLQEGTYTFNLKVTDSADQVSNKEVKVYVKPRVNVPPVAKASTTPDGIVTVRLPATEAVLNGSLSSDDDKIVKYQWEQTSGQQKLNIVDGDKPIAFVNDLKIGSFQFRLTVWDSDKQAGSDIVTLKVNENQNQKPKATVVESSEVYYLQPDLIKIDGSKSWDDHKIVKYQWIREDDSLAVGDILEKSYSESVXXXXXXXXXXYKFKLIVYDEEGLYDSAITSLQVFP 1598
K L V+ G+N+ + LP+N V L A V P Y ++W L + P D +G +EGK+++ L L L +G Y+F+++V G+ ++GE V V VKP STDDDKIV++HWE ++GP+ +E + D +L L ++ GNYTF LTV D+ G + T A L V DY P ++ G N ++ LP NS L G+ STDD + ++YEW S S G ++QGVR P L+LS +QEG YTF L VTDS+ Q +V V V+P N PPVA A PD +T LP L+GS S+DD KI Y WEQT G + + I + D +A V L+ G++ F LTV D SD VT+ E +Q P A V+SS L +DGS+S DD + Y W R+ S A GD+L S ++VL L L+ G Y F L V D +G + +++V P
Sbjct: 236 KELIVSAGENVEVTLPRNEVELNAFVVPAPPLGTAYVFDWSLKTHPKDY-SGEMEGKHSKTLKLSKLTVGLYEFEVIVDGDGAHGEGFVNVTVKPEPRVNKPPVAVVSPKSQEISLPISSTVIDGSQSTDDDKIVAWHWEEVKGPLREEKVSADTA-VLTL-TSLVPGNYTFSLTVTDSDGAQSSTQAMLSVNKAMDYRPVANAGANQVITLPRNSVTLYGNQSTDDHEPLAYEWSLSPESKGKVVEMQGVRTPTLQLSAMQEGDYTFQLTVTDSSGQQDTAQVTVIVQPENNKPPVADAG--PDKELT--LPVDHTTLDGSKSTDDQKIATYHWEQTKGPEGVKIENADSAVATVTGLQDGTYIFMLTVTDERNLHSSDTVTVTAREEVDQPPVAR-VQSSPSITLPVRTAVLDGSRSSDDKGSISYVWTRDGSSPAAGDVLNNSDHQAVLFLGNLVEGKYTFTLTVTDSKGQSHADTGTVEVRP 713 HSP 2 Score: 154.066 bits (388), Expect = 2.702e-39 Identity = 124/402 (30.85%), Postives = 192/402 (47.76%), Query Frame = 3
Query: 225 MVNVLVTKRLKVN-------IGKNITIFLPKNSVSLVANVSGNPNQKYDYEWDLVSKPSDQNAGNLEGKNNRELILKNLILGEYQFKLMVK---GNNSYGEALVFV--------FVKPG------------------STDDDKIVSYHWEII---QGPIVKENIMKDDQPMLQLDKTITQGNYTFKLTVKDTSGQLNFTIANLIVLPEKDYPPKSDPGPNMILNLPVNSAILNGSGSTDDKKIVSYEWSKVSDGLTADIQGVREPILKLSNLQEGTYTFNLKVTDSADQVSNKEVKVYVKPRVNVPPVAKASTTPDGIVTVRLPATEAVLNGSLSSDDDKIVKYQWEQTSGQQK----LNIVDGDKPIAFVNDLKIGSFQFRLTVWDSDKQAGSDIVTLKVN 1301
VNV V +VN K+ I LP +S + + S + ++ + W+ V P + + + L L +L+ G Y F L V G S +A++ V G STDD + ++Y W + +G +V+ ++ P LQL + +G+YTF+LTV D+SGQ + +IV PE + PP +D GP+ L LPV+ L+GS STDD+KI +Y W + I+ + ++ LQ+GTY F L VTD + S+ V V + V+ PPVA+ ++P ++ LP AVL+GS SSDD + Y W + LN D + + F+ +L G + F LTV DS Q+ +D T++V
Sbjct: 322 FVNVTVKPEPRVNKPPVAVVSPKSQEISLPISSTVIDGSQSTDDDKIVAWHWEEVKGPLREEKVS---ADTAVLTLTSLVPGNYTFSLTVTDSDGAQSSTQAMLSVNKAMDYRPVANAGANQVITLPRNSVTLYGNQSTDDHEPLAYEWSLSPESKGKVVEMQGVR--TPTLQL-SAMQEGDYTFQLTVTDSSGQQDTAQVTVIVQPENNKPPVADAGPDKELTLPVDHTTLDGSKSTDDQKIATYHWEQTKGPEGVKIENADSAVATVTGLQDGTYIFMLTVTDERNLHSSDTVTVTAREEVDQPPVARVQSSP----SITLPVRTAVLDGSRSSDDKGSISYVWTRDGSSPAAGDVLNNSD-HQAVLFLGNLVEGKYTFTLTVTDSKGQSHADTGTVEVR 712 HSP 3 Score: 112.849 bits (281), Expect = 1.039e-25 Identity = 95/300 (31.67%), Postives = 134/300 (44.67%), Query Frame = 3
Query: 228 VNVLVTKRLKVNIGKNITIFLPKNSVSLVANVSGNPNQKYDYEWDLVSKPSDQNAGNLEGKNNRELILKNLILGEYQFKLMVKGNNSYGE---ALVFVFVKP----------------------------GSTDDDKIVSYHWEIIQGPIVKENI-MKDDQPMLQLDKTITQGNYTFKLTVKDTSGQLNFTIANLIVLPEKDYPPKSDPGPNMILNLPVNSAILNGSGSTDDKKIVSYEWSKVSDGLTADIQGV-----REPILKLSNLQEGTYTFNLKVTDSADQVSNKEVKVYVKPRV 1016
VN + R N G N I LP+NSV+L N S + ++ YEW L S S ++G L L + G+Y F+L V +S G+ A V V V+P STDD KI +YHWE +GP E + +++ + + G Y F LTV D + + E D PP + + + LPV +A+L+GS S+DDK +SY W++ DG + V + +L L NL EG YTF L VTDS Q V V+P +
Sbjct: 424 VNKAMDYRPVANAGANQVITLPRNSVTLYGNQSTDDHEPLAYEWSL-SPESKGKVVEMQGVRTPTLQLSAMQEGDYTFQLTV--TDSSGQQDTAQVTVIVQPENNKPPVADAGPDKELTLPVDHTTLDGSKSTDDQKIATYHWEQTKGP---EGVKIENADSAVATVTGLQDGTYIFMLTVTDERNLHSSDTVTVTAREEVDQPPVARVQSSPSITLPVRTAVLDGSRSSDDKGSISYVWTR--DGSSPAAGDVLNNSDHQAVLFLGNLVEGKYTFTLTVTDSKGQSHADTGTVEVRPDI 715
BLAST of Dyslexia-associated protein KIAA0319-like protein vs. Ensembl Cavefish
Match: si:ch73-215d9.1 (dyslexia-associated protein KIAA0319 [Source:NCBI gene;Acc:103036464]) HSP 1 Score: 242.662 bits (618), Expect = 9.092e-70 Identity = 177/485 (36.49%), Postives = 245/485 (50.52%), Query Frame = 3
Query: 252 LKVNIGKNITIFLPKNSVSLVANVSGNPNQK--YDYEWDLVSKPSDQNAGNLEGKNNRELILKNLILGEYQFKLMVKGNNSYGEALVFVFVKP--------------------------------GSTDDDKIVSYHWEIIQGPIVKENIMKDDQPMLQLDKTITQGNYTFKLTVKDTSGQLNFTIANLIVLPEKDYPPKSDPGPNMILNLPVNSAILNGSGSTDDKKIVSYEWS--KVSDGLTADIQGVREPILKLSNLQEGTYTFNLKVTDSADQVSNKEVKVYVKPRVNVPPVAKASTTPDGIVTVRLPATEAVLNGSLSSDDDKIVKYQWEQTSGQQKLNIVDGDKPIAFVNDLKIGSFQFRLTVWDSDKQAGSDIVTLKVNENQNQKPKATVVESSEVYYLQPDLIKIDGSKSWDDHKIVKYQWIREDDSLAVGDILEKSYSESVXXXXXXXXXXYKFKLIVYDEEGLYDSAITSLQVFP 1598
L V I + LP+N++ L A+VS + Y YEW LVS PS+Q A +EGK++R + + +L G Y ++ VKG +YGE++ V P S+DD +V Y WE + GP+ K D P+L+L + IT G YTF+LTV D G + + A L V KD PP + G + ++ LP+N L + STDD I Y WS S A ++G+R L+LS LQEG YTF L VTDS+ Q + V V V P N PVA A PD + LP + +LNG+ SSDD I YQWE SG I D DK +A V L+ GS + +LTV D +A S ++T+ V E ++ P S L + + + GS S V Y W+R++ S A GD+L S E+ L L L+ G Y F+L V D +G SA +++V P
Sbjct: 320 LDVFIRSTGEVTLPENTIELTASVSPETETETPYTYEWSLVSSPSEQQA-EMEGKHSRTVKISDLSAGVYVVRVSVKGKEAYGESVGNFTVYPEERRNIPPKSVALPKHQDVSLSDGSIIFINGSQSSDDTGVVGYLWEQVDGPLWKSEAPMD-TPVLRL-QNITAGEYTFRLTVTDPEGLTDSSTATLTVSSPKDNPPVARAGSDQVITLPLNHLTLWANQSTDDLAITGYLWSLQSSSSAKAATMRGIRSLALQLSELQEGQYTFLLTVTDSSSQQDSDTVVVTVLPE-NRAPVAVAG--PDR--QLLLPTSSVMLNGTDSSDDQAITNYQWEILSGPPGSKIKDADKAVAMVTGLRAGSHKIKLTVQDQQGEADSAVITVTVTEAKS-LPLIAHASGSHTLTLPNNSLVLRGSASNCGSVNVSYLWVRDEQSPAAGDVLYGSDHEAFLYLANLVEGTYLFRLRVADSQGRSSSATATVEVRP 795
BLAST of Dyslexia-associated protein KIAA0319-like protein vs. Ensembl Cavefish
Match: si:ch73-215d9.1 (dyslexia-associated protein KIAA0319 [Source:NCBI gene;Acc:103036464]) HSP 1 Score: 242.662 bits (618), Expect = 9.092e-70 Identity = 177/485 (36.49%), Postives = 245/485 (50.52%), Query Frame = 3
Query: 252 LKVNIGKNITIFLPKNSVSLVANVSGNPNQK--YDYEWDLVSKPSDQNAGNLEGKNNRELILKNLILGEYQFKLMVKGNNSYGEALVFVFVKP--------------------------------GSTDDDKIVSYHWEIIQGPIVKENIMKDDQPMLQLDKTITQGNYTFKLTVKDTSGQLNFTIANLIVLPEKDYPPKSDPGPNMILNLPVNSAILNGSGSTDDKKIVSYEWS--KVSDGLTADIQGVREPILKLSNLQEGTYTFNLKVTDSADQVSNKEVKVYVKPRVNVPPVAKASTTPDGIVTVRLPATEAVLNGSLSSDDDKIVKYQWEQTSGQQKLNIVDGDKPIAFVNDLKIGSFQFRLTVWDSDKQAGSDIVTLKVNENQNQKPKATVVESSEVYYLQPDLIKIDGSKSWDDHKIVKYQWIREDDSLAVGDILEKSYSESVXXXXXXXXXXYKFKLIVYDEEGLYDSAITSLQVFP 1598
L V I + LP+N++ L A+VS + Y YEW LVS PS+Q A +EGK++R + + +L G Y ++ VKG +YGE++ V P S+DD +V Y WE + GP+ K D P+L+L + IT G YTF+LTV D G + + A L V KD PP + G + ++ LP+N L + STDD I Y WS S A ++G+R L+LS LQEG YTF L VTDS+ Q + V V V P N PVA A PD + LP + +LNG+ SSDD I YQWE SG I D DK +A V L+ GS + +LTV D +A S ++T+ V E ++ P S L + + + GS S V Y W+R++ S A GD+L S E+ L L L+ G Y F+L V D +G SA +++V P
Sbjct: 320 LDVFIRSTGEVTLPENTIELTASVSPETETETPYTYEWSLVSSPSEQQA-EMEGKHSRTVKISDLSAGVYVVRVSVKGKEAYGESVGNFTVYPEERRNIPPKSVALPKHQDVSLSDGSIIFINGSQSSDDTGVVGYLWEQVDGPLWKSEAPMD-TPVLRL-QNITAGEYTFRLTVTDPEGLTDSSTATLTVSSPKDNPPVARAGSDQVITLPLNHLTLWANQSTDDLAITGYLWSLQSSSSAKAATMRGIRSLALQLSELQEGQYTFLLTVTDSSSQQDSDTVVVTVLPE-NRAPVAVAG--PDR--QLLLPTSSVMLNGTDSSDDQAITNYQWEILSGPPGSKIKDADKAVAMVTGLRAGSHKIKLTVQDQQGEADSAVITVTVTEAKS-LPLIAHASGSHTLTLPNNSLVLRGSASNCGSVNVSYLWVRDEQSPAAGDVLYGSDHEAFLYLANLVEGTYLFRLRVADSQGRSSSATATVEVRP 795
BLAST of Dyslexia-associated protein KIAA0319-like protein vs. Ensembl Cavefish
Match: lrp11 (LDL receptor related protein 11 [Source:NCBI gene;Acc:103032685]) HSP 1 Score: 74.7146 bits (182), Expect = 9.287e-14 Identity = 38/90 (42.22%), Postives = 55/90 (61.11%), Query Frame = 3
Query: 735 DYPPKSDPGPNMILNLPVNSAILNGSGSTDDKKIVSYEWSKVSDGLTADIQGVREPILKLSNLQEGTYTFNLKVTDSADQVSNKEVKVYV 1004
D PP+SD G ++++ LP + AIL+G S DD I+ YEWS V + +++ +LKLS L+EG YTF L + D+ Q S+ V V V
Sbjct: 221 DEPPRSDAGQDVVVQLPTDWAILDGRDSIDDHGIMRYEWSLVKGDHSVNMKVTHPGLLKLSGLREGVYTFQLTIVDTIGQKSSDNVSVTV 310
BLAST of Dyslexia-associated protein KIAA0319-like protein vs. Ensembl Cavefish
Match: lrp11 (LDL receptor related protein 11 [Source:NCBI gene;Acc:103032685]) HSP 1 Score: 74.7146 bits (182), Expect = 9.497e-14 Identity = 38/90 (42.22%), Postives = 55/90 (61.11%), Query Frame = 3
Query: 735 DYPPKSDPGPNMILNLPVNSAILNGSGSTDDKKIVSYEWSKVSDGLTADIQGVREPILKLSNLQEGTYTFNLKVTDSADQVSNKEVKVYV 1004
D PP+SD G ++++ LP + AIL+G S DD I+ YEWS V + +++ +LKLS L+EG YTF L + D+ Q S+ V V V
Sbjct: 221 DEPPRSDAGQDVVVQLPTDWAILDGRDSIDDHGIMRYEWSLVKGDHSVNMKVTHPGLLKLSGLREGVYTFQLTIVDTIGQKSSDNVSVTV 310
BLAST of Dyslexia-associated protein KIAA0319-like protein vs. Ensembl Sea Lamprey
Match: si:ch211-193k19.1 (si:ch211-193k19.1 [Source:ZFIN;Acc:ZDB-GENE-060503-110]) HSP 1 Score: 300.827 bits (769), Expect = 1.845e-94 Identity = 190/487 (39.01%), Postives = 272/487 (55.85%), Query Frame = 3
Query: 246 KRLKVNIGKNITIFLPKNSVSLVANVSGNP--NQKYDYEWDLVSKPSDQNAGNLEGKNNRELILK-NLILGEYQFKLMVKGNNSYGEALVFVFVKPG-------------------------------STDDDKIVSYHWEIIQGPIVKENIMKDDQPMLQLDKTITQGNYTFKLTVKDTSGQLNFTIANLIVLPEKDYPPKSDPGPNMILNLPVNSAILNGSGSTDDKKIVSYEWSKVSD--GLTADIQGVREPILKLSNLQEGTYTFNLKVTDSADQVSNKEVKVYVKPRVNVPPVAKASTTPDGIVTVRLPATEAVLNGSLSSDDDKIVKYQWEQTSGQQKLNIVDGDKPIAFVNDLKIGSFQFRLTVWDSDKQAGSDIVTLKVNENQNQKPKATVVESSEVYYLQPDLIKIDGSKSWDDHKIVKYQWIREDDSLAVGDILEKSYSESVXXXXXXXXXXYKFKLIVYDEEGLYDSAITSLQVFP 1598
K L V+ G ++ + LPK+ V L A S P + Y YEW L+S P D G +E K++ ++ + L G Y +K+ V G N+YGE + V VKP S DDD I SY WE I+GP+ +E + + P+L L ++ G+YTF+LTV D+ G N+T AN+ V DYPP ++ GPN + LP N LNG+ S+DD IVSYEW+ S+ G ++QGVR P L+LS++QEG YTF L VTD+A+Q S EV V ++P N PPVA+A PD +T+ P L+GS S+DD I Y WE+ SG + + GD+ +A V++L++G++ F LTV D+ + S VT+ V E N+ P AT ++V L D + +DGS+SWDD + Y+W R+ S A G +L S VL LT L+ G Y F+L V D +G + +++V P
Sbjct: 4 KALVVSAGGSVEVTLPKDEVELNAVASPEPPAGETYQYEWMLISHPEDYQ-GAIEDKHHGGVLFRAQLSAGLYMYKVAVIGKNAYGEGFINVTVKPAPRVNQPPVAIVSPKSQEISLPTSSTFIDGKLSQDDDGIASYRWEQIRGPLHEERVT--NLPILHL-SSLVAGSYTFRLTVVDSDGVSNWTTANVTVNKAVDYPPVANAGPNQAITLPRNFVTLNGNQSSDDHGIVSYEWTLGSNTKGKVLEMQGVRTPYLQLSSMQEGDYTFQLTVTDAAEQQSTAEVTVVIQPENNRPPVAEAG--PDKELTI--PVDSTSLDGSKSTDDQGIASYHWEKISGPPGVRLDHGDEAVATVSELQVGTYVFSLTVLDAKGLSSSASVTVTVKEENNKPPHAT-AGGNKVLLLPDDTVMLDGSRSWDDQGSLSYEWTRDGSSPAAGVVLNGSEHHPVLWLTNLVEGTYVFRLRVTDNKGESSQDMATVEVKP 481 HSP 2 Score: 115.931 bits (289), Expect = 1.319e-27 Identity = 99/311 (31.83%), Postives = 139/311 (44.69%), Query Frame = 3
Query: 222 SMVNVLVTKRLK----VNIGKNITIFLPKNSVSLVANVSGNPNQKYDYEWDLVSKPSDQNAGNLEGKNNRELILKNLILGEYQFKLMVK-GNNSYGEALVFVFVKP----------------------------GSTDDDKIVSYHWEIIQGPIVKENIMKDDQPMLQLDK------TITQ---GNYTFKLTVKDTSGQLNFTIANLIVLPEKDYPPKSDPGPNMILNLPVNSAILNGSGSTDDKKIVSYEWSKVSDGLTADIQGV------REPILKLSNLQEGTYTFNLKVTDSADQVSNKEVKVYVKP 1010
+ NV V K + N G N I LP+N V+L N S + + YEW L S + ++G L L ++ G+Y F+L V A V V ++P STDD I SYHWE I GP P ++LD T+++ G Y F LTV D G + + V E + PP + G N +L LP ++ +L+GS S DD+ +SYEW++ DG ++ GV P+L L+NL EGTY F L+VTD+ + S V VKP
Sbjct: 186 TTANVTVNKAVDYPPVANAGPNQAITLPRNFVTLNGNQSSDDHGIVSYEWTLGSN-TKGKVLEMQGVRTPYLQLSSMQEGDYTFQLTVTDAAEQQSTAEVTVVIQPENNRPPVAEAGPDKELTIPVDSTSLDGSKSTDDQGIASYHWEKISGP-----------PGVRLDHGDEAVATVSELQVGTYVFSLTVLDAKGLSSSASVTVTVKEENNKPPHATAGGNKVLLLPDDTVMLDGSRSWDDQGSLSYEWTR--DG-SSPAAGVVLNGSEHHPVLWLTNLVEGTYVFRLRVTDNKGESSQDMATVEVKP 481
BLAST of Dyslexia-associated protein KIAA0319-like protein vs. Ensembl Nematostella
Match: EDO42871 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S0H0]) HSP 1 Score: 286.96 bits (733), Expect = 3.051e-89 Identity = 194/481 (40.33%), Postives = 257/481 (53.43%), Query Frame = 3
Query: 252 LKVNIGKNITIFLPKNSVSLVANVSGNPNQ----KYDYEWDLVSKPSDQNAGNLEGKNNRELILKNL-ILGEYQFKLMVKG-NNSYGEALVFVFVKPG-------------------------------STDDDKIVSYHWEIIQGPIVKENIM---KDDQPMLQLDKTITQGNYTFKLTVKDTSGQLNFTIANLIVLPEKDYPPKSDPGPNMILNLPVNSAILNGSGSTDDKKIVSYEWSKV-SDGLTADIQGVREPILKLSNLQEGTYTFNLKVTDSADQVSNKEVKVYVKPRVNVPPVAKASTTPDGIVTVRLPATEAVLNGSLSSDDDKIVKYQWEQTSGQQKLNIVDGDKPIAFVNDLKIGSFQFRLTVWDSDKQAGSDIVTLKVNENQNQKPKATVVESSEVYYLQPDLIKIDGSKSWDDHKIVKYQWIREDDSLAVGDILEKSYSESVXXXXXXXXXXYKFKLIVYDEEGLYDS 1571
+ V+ G N + LP NS+ L A S P + Y Y W +S P + G +EGK+ R +IL L +G YQFK+ V G N+++G A V V VKP STDDDKIV Y WE ++GP+ +N M D P+LQL K++ G YTFKLTV D+ G+ + T A + V EKDYPP + G +++L LPVN +L G+ STDDK I SYEWSK S D+QG P LK+SN+ G YTF LKVTD+ Q + V V V+P N PPVAKA + D + P L+ S DD KIVKY W+Q SG + D + V L G + F+LTV D GS V + V ++ NQ P A V +L ++DGSKS DDH I +Y W R+ S A GD++ S +++L L+ L+ G+YKFKL V D +GL S
Sbjct: 1 MLVSAGDNKVLTLPVNSIELYA--SAFPKETIDNHYTYHWQQISAPQGSH-GYMEGKDTRRVILSKLSHIGTYQFKVTVTGANHAFGVAHVNVTVKPAPRVNKPPRADISPKEQTITLPTNEVVLDGSKSTDDDKIVEYKWEEMKGPLNDKNKMISQGADSPVLQL-KSLVPGIYTFKLTVSDSDGETDSTTAVVTVNDEKDYPPVARAGNDVVLTLPVNHVVLYGNSSTDDKGIASYEWSKTPSSPAVGDMQGTNSPQLKVSNMVLGDYTFVLKVTDTGGQSATSRVTVVVQPEKNTPPVAKAGSDKDLV----YPDDTTTLDAKGSYDDQKIVKYHWDQVSGPSSAEMSGADNQVVEVKKLTEGHYVFKLTVTDDKGLTGSGTVAVNVKKDVNQAPVAR-AGPDVVVHLPNRAAELDGSKSSDDHGIAQYLWTRDAKSPAAGDVINSSNHQAILRLSNLVEGMYKFKLTVLDAKGLKSS 472 HSP 2 Score: 154.836 bits (390), Expect = 1.446e-40 Identity = 123/381 (32.28%), Postives = 182/381 (47.77%), Query Frame = 3
Query: 270 KNITIFLPKNSVSLVANVSGNPNQKYDYEWDLVSKP-SDQNAGNLEGKNNRELILKNLILGEYQFKLMVK---GNNSYGEALVFV--------FVKPG------------------STDDDKIVSYHWEIIQGPIVKENIMKDDQPMLQLDKTITQGNYTFKLTVKDTSGQLNFTIANLIVLPEKDYPPKSDPGPNMILNLPVNSAILNGSGSTDDKKIVSYEWSKVSDGLTADIQGVREPILKLSNLQEGTYTFNLKVTDSADQVSNKEVKVYVKPRVNVPPVAKASTTPDGIVTVRLPATEAVLNGSLSSDDDKIVKYQWEQTSGQQKLNIV---DGDKPIAFVNDLKIGSFQFRLTVWDSDKQAGSDIVTLKVNENQN 1313
K TI LP N V L + S + ++ +Y+W+ + P +D+N +G ++ L LK+L+ G Y FKL V G A+V V + G STDD I SY W ++ + P L++ + G+YTF L V DT GQ + ++V PEK+ PP + G + L P ++ L+ GS DD+KIV Y W +VS +A++ G ++++ L EG Y F L VTD + V V VK VN PVA+A PD V V LP A L+GS SSDD I +Y W + + V + I +++L G ++F+LTV D+ SD L V E+++
Sbjct: 109 KEQTITLPTNEVVLDGSKSTDDDKIVEYKWEEMKGPLNDKNKMISQGADSPVLQLKSLVPGIYTFKLTVSDSDGETDSTTAVVTVNDEKDYPPVARAGNDVVLTLPVNHVVLYGNSSTDDKGIASYEWSKTPSSPAVGDMQGTNSPQLKVSNMVL-GDYTFVLKVTDTGGQSATSRVTVVVQPEKNTPPVAKAGSDKDLVYPDDTTTLDAKGSYDDQKIVKYHWDQVSGPSSAEMSGADNQVVEVKKLTEGHYVFKLTVTDDKGLTGSGTVAVNVKKDVNQAPVARAG--PD--VVVHLPNRAAELDGSKSSDDHGIAQYLWTRDAKSPAAGDVINSSNHQAILRLSNLVEGMYKFKLTVLDAKGLKSSDEALLTVKEDEH 484 HSP 3 Score: 152.525 bits (384), Expect = 1.078e-39 Identity = 116/361 (32.13%), Postives = 173/361 (47.92%), Query Frame = 3
Query: 540 DKIVSYHWEIIQGPIVKENIMKD-DQPMLQLDKTITQGNYTFKLTVKDTSGQLNFTIANLIV--LPEKDYPPKSDPGP-NMILNLPVNSAILNGSGSTDDKKIVSYEWSKVSDGLTAD----IQGVREPILKLSNLQEGTYTFNLKVTDSADQVSNKEVKVYVKPRVNVPPVAKASTTPDGIVTVRLPATEAVLNGSLSSDDDKIVKYQWEQTSGQQKLNIVDG-DKPIAFVNDLKIGSFQFRLTVWDSDKQAGSDIVTLKVNENQNQKPKATVVESSEVYYLQPDLIKIDGSKSWDDHKIVKYQWIREDDSLAVGDILEKSYSES-VXXXXXXXXXXYKFKLIVYDEEGLYDSAITSLQV 1592
D +YHW+ I P M+ D + L K G Y FK+TV + N+ V P + PP++D P + LP N +L+GS STDD KIV Y+W ++ L QG P+L+L +L G YTF L V+DS + + V V + PPVA+A V + LP VL G+ S+DD I Y+W +T + + G + P V+++ +G + F L V D+ Q+ + VT+ V +N P A ++ Y D +D S+DD KIVKY W D ++ E S +++ V+ + L G Y FKL V D++GL S ++ V
Sbjct: 31 DNHYTYHWQQISAPQGSHGYMEGKDTRRVILSKLSHIGTYQFKVTVTGANHAFGVAHVNVTVKPAPRVNKPPRADISPKEQTITLPTNEVVLDGSKSTDDDKIVEYKWEEMKGPLNDKNKMISQGADSPVLQLKSLVPGIYTFKLTVSDSDGETDSTTAVVTVNDEKDYPPVARAGND----VVLTLPVNHVVLYGNSSTDDKGIASYEWSKTPSSPAVGDMQGTNSPQLKVSNMVLGDYTFVLKVTDTGGQSATSRVTVVVQPEKNTPPVAKAGSDKDLVY-PDDTTTLDAKGSYDDQKIVKYHW----DQVSGPSSAEMSGADNQVVEVKKLTEGHYVFKLTVTDDKGLTGSGTVAVNV 382 HSP 4 Score: 121.324 bits (303), Expect = 3.476e-29 Identity = 91/280 (32.50%), Postives = 137/280 (48.93%), Query Frame = 3
Query: 267 GKNITIFLPKNSVSLVANVSGNPNQKYDYEWDLVSKPSDQNAGNLEGKNNRELILKNLILGEYQFKLMV--KGNNSYGEALVFVFVKP----------------------------GSTDDDKIVSYHWEIIQGPIVKENIMKDDQPMLQLDKTITQGNYTFKLTVKDTSGQLNFTIANLIVLPEKDYPPKSDPGPNMILNLPVNSAILNGSGSTDDKKIVSYEWSKVSDGLTA-DI--QGVREPILKLSNLQEGTYTFNLKVTDSADQVSNKEVKVYVK 1007
G ++ + LP N V L N S + YEW PS G+++G N+ +L + N++LG+Y F L V G S + V V V+P GS DD KIV YHW+ + GP E D+Q ++++ K +T+G+Y FKLTV D G + V + + P + GP+++++LP +A L+GS S+DD I Y W++ + A D+ + IL+LSNL EG Y F L V D+ S+ E + VK
Sbjct: 206 GNDVVLTLPVNHVVLYGNSSTDDKGIASYEWS--KTPSSPAVGDMQGTNSPQLKVSNMVLGDYTFVLKVTDTGGQS-ATSRVTVVVQPEKNTPPVAKAGSDKDLVYPDDTTTLDAKGSYDDQKIVKYHWDQVSGPSSAEMSGADNQ-VVEVKK-LTEGHYVFKLTVTDDKGLTGSGTVAVNVKKDVNQAPVARAGPDVVVHLPNRAAELDGSKSSDDHGIAQYLWTRDAKSPAAGDVINSSNHQAILRLSNLVEGMYKFKLTVLDAKGLKSSDEALLTVK 480
BLAST of Dyslexia-associated protein KIAA0319-like protein vs. Ensembl Medaka
Match: si:ch211-193k19.1 (KIAA0319 like [Source:NCBI gene;Acc:101168634]) HSP 1 Score: 296.59 bits (758), Expect = 1.001e-89 Identity = 192/484 (39.67%), Postives = 266/484 (54.96%), Query Frame = 3
Query: 246 KRLKVNIGKNITIFLPKNSVSLVANV--SGNPNQKYDYEWDLVSKPSDQNAGNLEGKNNRELILKNLILGEYQFKLMVKGNNSYGEALVFVFVKP-------------------------------GSTDDDKIVSYHWEIIQGPIVKENIMKDDQPMLQLDKTITQGNYTFKLTVKDTSGQLNFTIANLIVLPEKDYPPKSDPGPNMILNLPVNSAILNGSGSTDDKKIVSYEW--SKVSDGLTADIQGVREPILKLSNLQEGTYTFNLKVTDSADQVSNKEVKVYVKPRVNVPPVAKASTTPDGIVTVRLPATEAVLNGSLSSDDDKIVKYQWEQTSGQQKLNIVDGDKPIAFVNDLKIGSFQFRLTVWDSDKQAGSDIVTLKVNENQNQKPKATVVESSEVYYLQPDLIKIDGSKSWDDHKIVKYQWIREDDSLAVGDILEKSYSESVXXXXXXXXXXYKFKLIVYDEEGLYDSAITSLQV 1592
K L V+ G+++ + LP+N V L A V + P Y ++W L++ P D +G +EGK ++ L L L +G Y+F + V G +++GE V V VKP STDDDK+V++HWE ++GP+ +E ++ D + +L L + GNYTF LTV DT G N T A L V KDY P S+ GPN ++ LP NS L G+ STDD +SYEW S S ++QGVR PIL+LS +QEG YTF L VTDS+ Q V V V+P N PVA A P+ +T LP L+GS SSDD +I Y+W +TSG + I + D IA V L++G++ F LTV D SD VT+ V E ++Q P A V+ S + L +DGS S DD + Y W R+D S A G++L S ++VL L L+ G Y+FKL V D +G S +++V
Sbjct: 217 KELVVSAGESVEVTLPRNEVELNAFVLPTPPPGTNYAFDWRLITHPKDY-SGEMEGKKSKTLKLSQLTVGLYEFGVTVDGEDAHGEGFVNVTVKPEPRVNKPPVAVVSPKFQEISLPTSSTVIDGSQSTDDDKVVAWHWEEVKGPLREEKVLADTK-ILTL-TNLVPGNYTFSLTVTDTDGATNSTQATLSVNKAKDYRPISNAGPNQVIQLPRNSITLYGNQSTDDHDSLSYEWSLSPESKDKVVEMQGVRTPILQLSAMQEGDYTFQLTVTDSSGQQDTSHVTVIVQPENNKAPVANAG--PEKELT--LPVDRTTLDGSKSSDDQRIATYRWTKTSGPDGVKIENADSAIATVTGLEVGTYTFMLTVTDDRNLENSDTVTVIVREEKDQPPVARVISSPPI-SLPVRTASLDGSHSTDDEGGLSYLWTRDDSSPAAGEVLNNSDHQAVLFLGNLVEGKYRFKLTVTDSKGQSSSDSGTVEV 692 HSP 2 Score: 147.132 bits (370), Expect = 5.579e-37 Identity = 122/404 (30.20%), Postives = 197/404 (48.76%), Query Frame = 3
Query: 282 IFLPKNSVSLVANVSGNPNQKYDYEWDLVSKPSDQNAGNLEGKNNRELILKNLILGEYQFKLMVK---GNNSYGEALVFV--------------------------FVKPGSTDDDKIVSYHWEIIQGPIVKENIMKDD---QPMLQLDKTITQGNYTFKLTVKDTSGQLNFTIANLIVLPEKDYPPKSDPGPNMILNLPVNSAILNGSGSTDDKKIVSYEWSKVSDGLTADIQGVREPILKLSNLQEGTYTFNLKVTDSADQVSNKEVKVYVKPRVNVPPVAKASTTPDGIVTVRLPATEAVLNGSLSSDDDKIVKYQWEQ----TSGQQKLNIVDGDKPIAFVNDLKIGSFQFRLTVWDSDKQAGSDIVTLKVNENQNQKPKATV---VESSEVYYLQPDLI 1376
I LP +S + + S + ++ + W+ V P + + K L L NL+ G Y F L V G + +A + V STDD +SY W + P K+ +++ P+LQL + +G+YTF+LTV D+SGQ + + +IV PE + P ++ GP L LPV+ L+GS S+DD++I +Y W+K S I+ I ++ L+ GTYTF L VTD + ++ V V V+ + PPVA+ ++P + LP A L+GS S+DD+ + Y W + + + LN D + + F+ +L G ++F+LTV DS Q+ SD T++V + +K + V S+V+ Q DL+
Sbjct: 329 ISLPTSSTVIDGSQSTDDDKVVAWHWEEVKGPLREEKVLADTKI---LTLTNLVPGNYTFSLTVTDTDGATNSTQATLSVNKAKDYRPISNAGPNQVIQLPRNSITLYGNQSTDDHDSLSYEWSL--SPESKDKVVEMQGVRTPILQL-SAMQEGDYTFQLTVTDSSGQQDTSHVTVIVQPENNKAPVANAGPEKELTLPVDRTTLDGSKSSDDQRIATYRWTKTSGPDGVKIENADSAIATVTGLEVGTYTFMLTVTDDRNLENSDTVTVIVREEKDQPPVARVISSP----PISLPVRTASLDGSHSTDDEGGLSYLWTRDDSSPAAGEVLNNSD-HQAVLFLGNLVEGKYRFKLTVTDSKGQSSSDSGTVEVKADPWEKDLVELVLEVPVSQVFQRQRDLL 721 HSP 3 Score: 100.523 bits (249), Expect = 7.761e-22 Identity = 81/258 (31.40%), Postives = 131/258 (50.78%), Query Frame = 3
Query: 840 SYEWSKVSD--GLTADIQGVREPILKLSNLQEGTYTFNLKVTDSADQVSNKEVKVYVKP--RVNVPPVAKASTTPDGIVTVRLPATEAVLNGSLSSDDDKIVKYQWEQTSGQQKLNIVDGDKPIAFVNDLKIGSFQFRLTVWDSDKQAGSDIVTLKVNENQNQKPKATVVESSEVYYLQPDLIKIDGSKSWDDHKIVKYQWIREDDSLAVGDILE-KSYSESVXXXXXXXXXXYKFKLIVYDEEGLYDSAITSLQVFP 1598
+++W ++ + +++G + LKLS L G Y F + V D D V V VKP RVN PPVA S + LP + V++GS S+DDDK+V + WE+ G + V D I + +L G++ F LTV D+D S TL VN+ ++ +P + ++V L + I + G++S DDH + Y+W +S ++E + +L L+ + G Y F+L V D G D++ ++ V P
Sbjct: 253 AFDWRLITHPKDYSGEMEGKKSKTLKLSQLTVGLYEFGVTV-DGEDAHGEGFVNVTVKPEPRVNKPPVAVVSPK---FQEISLPTSSTVIDGSQSTDDDKVVAWHWEEVKGPLREEKVLADTKILTLTNLVPGNYTFSLTVTDTDGATNSTQATLSVNKAKDYRPISN-AGPNQVIQLPRNSITLYGNQSTDDHDSLSYEWSLSPES--KDKVVEMQGVRTPILQLSAMQEGDYTFQLTVTDSSGQQDTSHVTVIVQP 503 HSP 4 Score: 99.3673 bits (246), Expect = 1.786e-21 Identity = 92/288 (31.94%), Postives = 128/288 (44.44%), Query Frame = 3
Query: 261 NIGKNITIFLPKNSVSLVANVSGNPNQKYDYEWDLVSKPSDQNAGNLEGKNNRELILKNLILGEYQFKLMVKGNNSYGE---ALVFVFVKP----------------------------GSTDDDKIVSYHWEIIQGP-IVKENIMKDDQPMLQLDKTITQGNYTFKLTVKDTSGQLNFTIANLIVLPEKDYPPKSDPGPNMILNLPVNSAILNGSGSTDDKKIVSYEWSKVSDGLTA-------DIQGVREPILKLSNLQEGTYTFNLKVTDSADQVSNKEVKVYVK 1007
N G N I LP+NS++L N S + + YEW L + D+ ++G L L + G+Y F+L V +S G+ + V V V+P S+DD +I +Y W GP VK +++ + + G YTF LTV D N +IV EKD PP + + ++LPV +A L+GS STDD+ +SY W++ A D Q V L L NL EG Y F L VTDS Q S+ V VK
Sbjct: 416 NAGPNQVIQLPRNSITLYGNQSTDDHDSLSYEWSLSPESKDKVV-EMQGVRTPILQLSAMQEGDYTFQLTV--TDSSGQQDTSHVTVIVQPENNKAPVANAGPEKELTLPVDRTTLDGSKSSDDQRIATYRWTKTSGPDGVK---IENADSAIATVTGLEVGTYTFMLTVTDDRNLENSDTVTVIVREEKDQPPVARVISSPPISLPVRTASLDGSHSTDDEGGLSYLWTRDDSSPAAGEVLNNSDHQAV----LFLGNLVEGKYRFKLTVTDSKGQSSSDSGTVEVK 693
BLAST of Dyslexia-associated protein KIAA0319-like protein vs. Ensembl Medaka
Match: lrp11 (low-density lipoprotein receptor-related protein 11 [Source:NCBI gene;Acc:101175213]) HSP 1 Score: 69.707 bits (169), Expect = 3.444e-12 Identity = 33/88 (37.50%), Postives = 54/88 (61.36%), Query Frame = 3
Query: 741 PPKSDPGPNMILNLPVNSAILNGSGSTDDKKIVSYEWSKVSDGLTADIQGVREPILKLSNLQEGTYTFNLKVTDSADQVSNKEVKVYV 1004
PP+S+ G ++++ LP + A+L+G S DD I Y+W+ V +++ +LK+S LQEG YTF + +TD++ Q S+ V V V
Sbjct: 190 PPRSNAGQDVVIQLPTDWAVLDGRDSVDDHGIDRYDWTLVKGDTAINMKSTHPGLLKVSGLQEGVYTFQMTITDTSGQKSSDNVSVTV 277
BLAST of Dyslexia-associated protein KIAA0319-like protein vs. Ensembl Medaka
Match: si:ch73-215d9.1 (dyslexia-associated protein KIAA0319 homolog [Source:NCBI gene;Acc:101173681]) HSP 1 Score: 62.7734 bits (151), Expect = 6.176e-10 Identity = 49/204 (24.02%), Postives = 76/204 (37.25%), Query Frame = 3
Query: 531 TDDDKIVSYHWEIIQGPIVKENIMKDDQPMLQLDKTITQGNYTFKLTVKDTSGQLNFTIANLIVLPEKDYPPKSDPGPNMILNLPVNSAILNGSGSTDDKKIVSYEWSKVSDGLTADIQGVR--------------------------------------------EPILKLSNLQEGTYTFNLKVTDSADQVSNKEVKVYVKP 1010
T + S+ WE + GP ++++ + ++ G Y F+LTV D G + + V PP + + L LP NS +L GS S D+ V + W++ A + G +P L L++L EGTY F LKVTD+ + S V V+P
Sbjct: 299 TGGRAVSSFRWEAVSGP--PGFLLQNADRAVATVTSVQPGRYVFRLTVSDQEGATDSASLTVRVQEASSPPPVAHASGSHTLTLPNNSLVLRGSVSDGDQSRVHFLWTRDPQSPAAGVSGAEQNMRHLGRNRNSEEQRLLYSQDGYPSFRRNASALLQVVLFGSRTQPSLFLADLVEGTYLFQLKVTDAQGRSSVAMATVEVRP 500 HSP 2 Score: 56.9954 bits (136), Expect = 3.389e-8 Identity = 46/142 (32.39%), Postives = 68/142 (47.89%), Query Frame = 3
Query: 750 SDPGPNMILN------LPVNSAILNGSGSTD--DKKIVSYEWSKVSDGLTADIQGVREPILKLSNLQEGTYTFNLKVTDSADQVSNKEVKVYVKPRVNVPPVAKASTTPDGIVTVRLPATEAVLNGSLSSDDDKIVKYQWEQ 1151
SDPGP + LP++S +LNGS ST + + S+ W VS +Q + ++++Q G Y F L V+D + + V V+ + PPVA AS G T+ LP VL GS+S D V + W +
Sbjct: 268 SDPGPVAVAGPDRRLVLPLSSVLLNGSSSTGTGGRAVSSFRWEAVSGPPGFLLQNADRAVATVTSVQPGRYVFRLTVSDQEGATDSASLTVRVQEASSPPPVAHAS----GSHTLTLPNNSLVLRGSVSDGDQSRVHFLWTR 405 HSP 3 Score: 54.299 bits (129), Expect = 2.909e-7 Identity = 36/123 (29.27%), Postives = 57/123 (46.34%), Query Frame = 3
Query: 1098 NGSLSSD--DDKIVKYQWEQTSGQQKLNIVDGDKPIAFVNDLKIGSFQFRLTVWDSDKQAGSDIVTLKVNENQNQKPKATVVESSEVYYLQPDLIKIDGSKSWDDHKIVKYQWIREDDSLAVG 1460
NGS S+ + ++WE SG + + D+ +A V ++ G + FRLTV D + S +T++V E + P A S L + + + GS S D V + W R+ S A G
Sbjct: 292 NGSSSTGTGGRAVSSFRWEAVSGPPGFLLQNADRAVATVTSVQPGRYVFRLTVSDQEGATDSASLTVRVQEASSPPPVAH-ASGSHTLTLPNNSLVLRGSVSDGDQSRVHFLWTRDPQSPAAG 413
BLAST of Dyslexia-associated protein KIAA0319-like protein vs. Ensembl Medaka
Match: spint1a (kunitz-type protease inhibitor 1 [Source:NCBI gene;Acc:101175207]) HSP 1 Score: 56.225 bits (134), Expect = 4.692e-8 Identity = 36/91 (39.56%), Postives = 52/91 (57.14%), Query Frame = 3
Query: 735 DYPPKSDPGPNMILNLPVNSAILNGSGSTDDKKIVSYEWSKVSDGLTADIQGVREP-ILKLSNLQEGTYTFNLKVTDSADQVSNKEVKVYV 1004
D PP ++ GP++++ P ++ LNG S DDK IV+YEW +S A I+ + P + +SNL G Y FNL V D+ Q + V V V
Sbjct: 135 DAPPVANGGPDIVVQ-PNDAVTLNGIQSKDDKGIVTYEWQMLSPYPFAVIERTKFPDQVVVSNLTAGRYKFNLTVIDTIGQSDSTVVTVLV 224
BLAST of Dyslexia-associated protein KIAA0319-like protein vs. Ensembl Medaka
Match: si:ch73-215d9.1 (dyslexia-associated protein KIAA0319 homolog [Source:NCBI gene;Acc:101173681]) HSP 1 Score: 56.6102 bits (135), Expect = 4.997e-8 Identity = 34/90 (37.78%), Postives = 47/90 (52.22%), Query Frame = 3
Query: 741 PPKSDPGPNMILNLPVNSAILNGSGSTDDKKIVSYEWSKVSDGLTADIQGVREPILKLSNLQEGTYTFNLKVTDSADQVSNKEVKVYVKP 1010
PP + + L LP NS +L GS S D+ V + W++ A + G P L L++L EGTY F LKVTD+ + S V V+P
Sbjct: 397 PPVAHASGSHTLTLPNNSLVLRGSVSDGDQSRVHFLWTRDPQSPAAGVSG---PSLFLADLVEGTYLFQLKVTDAQGRSSVAMATVEVRP 483 HSP 2 Score: 51.6026 bits (122), Expect = 2.010e-6 Identity = 66/226 (29.20%), Postives = 97/226 (42.92%), Query Frame = 3
Query: 750 SDPGPNMILN------LPVNSAILNGSGS--TDDKKIVSYEWSKVSDGLTADIQGVREPILKLSNLQEGTYTFNLKVTDSADQVSNKEVKVY-----VKPRVNV-PPVAKASTTPDGIVTVRLPATEAVLNGSLSSDDDKIVKYQWEQTSGQQKLNIVDGDKPIAFVNDLKIGSFQFRLTVWDSDKQAGSDIVTLKVN---ENQNQKPKATVVESSEVYYLQPDLI 1376
SDPGP + LP++S +LNGS S T + + S+ W V GL ++G T + KV ++ V V V+P + PPVA AS G T+ LP VL GS+S D V + W + Q V G P F+ DL G++ F+L V D+ ++ + T++V Q +V S+V LQ D +
Sbjct: 305 SDPGPVAVAGPDRRLVLPLSSVLLNGSSSTGTGGRAVSSFRWEAVRRGLIISVRGA-------------TSSGFRKVRGGLCSINMTSVVVLIRLWSVRPAASSPPPVAHAS----GSHTLTLPNNSLVLRGSVSDGDQSRVHFLWTRDP-QSPAAGVSG--PSLFLADLVEGTYLFQLKVTDAQGRSSVAMATVEVRPEPAGGEQVELEMLVPVSQVSVLQRDTV 510
BLAST of Dyslexia-associated protein KIAA0319-like protein vs. Planmine SMEST
Match: SMESG000079575.1 (SMESG000079575.1) HSP 1 Score: 909.827 bits (2350), Expect = 0.000e+0 Identity = 488/538 (90.71%), Postives = 489/538 (90.89%), Query Frame = 3
Query: 75 SVSMPNISTTVSTNLTSNHVINXXXXXXXXXXXXPISWIFILFYIR*T*SMVNVLVTKRLKVNIGKNITIFLPKNSVSLVANVSGNPNQKYDYEWDLVSKPSDQNAGNLEGKNNRELILKNLILGEYQFKLMVKGNNSYGEALVFVFVKP------------------------------GSTDDDKIVSYHWEIIQGPIVKENIMKDDQPMLQLDKTITQGNYTFKLTVKDTSGQLNFTIANLIVLPEKDYPPKSDPGPNMILNLPVNSAILNGSGSTDDKKIVSYEWSKVSDGLTADIQGVREPILKLSNLQEGTYTFNLKVTDSADQVSNKEVKVYVKPRVNVPPVAKASTTPDGIVTVRLPATEAVLNGSLSSDDDKIVKYQWEQTSGQQKLNIVDGDKPIAFVNDLKIGSFQFRLTVWDSDKQAGSDIVTLKVNENQNQKPKATVVESSEVYYLQPDLIKIDGSKSWDDHKIVKYQWIREDDSLAVGDILEKSYSESVXXXXXXXXXXYKFKLIVYDEEGLYDSAITSLQVFP 1598
SVSMPNISTTVSTNLTSNHVINTTTKTFTEKMSTPI +TKRLKVNIGKNITIFLPKNSVSLVANVSGNPNQKYDYEWDLVSKPSDQNAGNLEGKNNRELILKNLILGEYQFKLMVKGNNSYGEALVFVFVKP GSTDDDKIVSYHWEIIQGPIVKENIMKDDQPMLQLDKTITQGNYTFKLTVKDTSGQLNFTIANLIVLPEKDYPPKSDPGPNMILNLPVNSAILNGSGSTDDKKIVSYEWSKVSDGLTADIQGVREPILKLSNLQEGTYTFNLKVTDSADQVSNKEVKVYVKPRVNVPPVAKASTTPDGIVTVRLPATEAVLNGSLSSDDDKIVKYQWEQTSGQQKLNIVDGDKPIAFVNDLKIGSFQFRLTVWDSDKQAGSDIVTLKVNENQNQKPKATVVESSEVYYLQPDLIKIDGSKSWDDHKIVKYQWIREDDSLAVGDILEKSYSESVLLLTGLLPGLYKFKLIVYDEEGLYDSAITSLQVFP
Sbjct: 99 SVSMPNISTTVSTNLTSNHVINTTTKTFTEKMSTPI-------------------ITKRLKVNIGKNITIFLPKNSVSLVANVSGNPNQKYDYEWDLVSKPSDQNAGNLEGKNNRELILKNLILGEYQFKLMVKGNNSYGEALVFVFVKPEKKKDQPPIAIIKPSTQTVQLPNNVILDGSGSTDDDKIVSYHWEIIQGPIVKENIMKDDQPMLQLDKTITQGNYTFKLTVKDTSGQLNFTIANLIVLPEKDYPPKSDPGPNMILNLPVNSAILNGSGSTDDKKIVSYEWSKVSDGLTADIQGVREPILKLSNLQEGTYTFNLKVTDSADQVSNKEVKVYVKPRVNVPPVAKASTTPDGIVTVRLPATEAVLNGSLSSDDDKIVKYQWEQTSGQQKLNIVDGDKPIAFVNDLKIGSFQFRLTVWDSDKQAGSDIVTLKVNENQNQKPKATVVESSEVYYLQPDLIKIDGSKSWDDHKIVKYQWIREDDSLAVGDILEKSYSESVLLLTGLLPGLYKFKLIVYDEEGLYDSAITSLQVFP 617
BLAST of Dyslexia-associated protein KIAA0319-like protein vs. Planmine SMEST
Match: SMESG000079575.1 (SMESG000079575.1) HSP 1 Score: 907.516 bits (2344), Expect = 0.000e+0 Identity = 488/538 (90.71%), Postives = 489/538 (90.89%), Query Frame = 3
Query: 75 SVSMPNISTTVSTNLTSNHVINXXXXXXXXXXXXPISWIFILFYIR*T*SMVNVLVTKRLKVNIGKNITIFLPKNSVSLVANVSGNPNQKYDYEWDLVSKPSDQNAGNLEGKNNRELILKNLILGEYQFKLMVKGNNSYGEALVFVFVKP------------------------------GSTDDDKIVSYHWEIIQGPIVKENIMKDDQPMLQLDKTITQGNYTFKLTVKDTSGQLNFTIANLIVLPEKDYPPKSDPGPNMILNLPVNSAILNGSGSTDDKKIVSYEWSKVSDGLTADIQGVREPILKLSNLQEGTYTFNLKVTDSADQVSNKEVKVYVKPRVNVPPVAKASTTPDGIVTVRLPATEAVLNGSLSSDDDKIVKYQWEQTSGQQKLNIVDGDKPIAFVNDLKIGSFQFRLTVWDSDKQAGSDIVTLKVNENQNQKPKATVVESSEVYYLQPDLIKIDGSKSWDDHKIVKYQWIREDDSLAVGDILEKSYSESVXXXXXXXXXXYKFKLIVYDEEGLYDSAITSLQVFP 1598
SVSMPNISTTVSTNLTSNHVINTTTKTFTEKMSTPI +TKRLKVNIGKNITIFLPKNSVSLVANVSGNPNQKYDYEWDLVSKPSDQNAGNLEGKNNRELILKNLILGEYQFKLMVKGNNSYGEALVFVFVKP GSTDDDKIVSYHWEIIQGPIVKENIMKDDQPMLQLDKTITQGNYTFKLTVKDTSGQLNFTIANLIVLPEKDYPPKSDPGPNMILNLPVNSAILNGSGSTDDKKIVSYEWSKVSDGLTADIQGVREPILKLSNLQEGTYTFNLKVTDSADQVSNKEVKVYVKPRVNVPPVAKASTTPDGIVTVRLPATEAVLNGSLSSDDDKIVKYQWEQTSGQQKLNIVDGDKPIAFVNDLKIGSFQFRLTVWDSDKQAGSDIVTLKVNENQNQKPKATVVESSEVYYLQPDLIKIDGSKSWDDHKIVKYQWIREDDSLAVGDILEKSYSESVLLLTGLLPGLYKFKLIVYDEEGLYDSAITSLQVFP
Sbjct: 18 SVSMPNISTTVSTNLTSNHVINTTTKTFTEKMSTPI-------------------ITKRLKVNIGKNITIFLPKNSVSLVANVSGNPNQKYDYEWDLVSKPSDQNAGNLEGKNNRELILKNLILGEYQFKLMVKGNNSYGEALVFVFVKPEKKKDQPPIAIIKPSTQTVQLPNNVILDGSGSTDDDKIVSYHWEIIQGPIVKENIMKDDQPMLQLDKTITQGNYTFKLTVKDTSGQLNFTIANLIVLPEKDYPPKSDPGPNMILNLPVNSAILNGSGSTDDKKIVSYEWSKVSDGLTADIQGVREPILKLSNLQEGTYTFNLKVTDSADQVSNKEVKVYVKPRVNVPPVAKASTTPDGIVTVRLPATEAVLNGSLSSDDDKIVKYQWEQTSGQQKLNIVDGDKPIAFVNDLKIGSFQFRLTVWDSDKQAGSDIVTLKVNENQNQKPKATVVESSEVYYLQPDLIKIDGSKSWDDHKIVKYQWIREDDSLAVGDILEKSYSESVLLLTGLLPGLYKFKLIVYDEEGLYDSAITSLQVFP 536
BLAST of Dyslexia-associated protein KIAA0319-like protein vs. Planmine SMEST
Match: SMESG000063418.1 (SMESG000063418.1) HSP 1 Score: 75.0998 bits (183), Expect = 2.395e-14 Identity = 52/154 (33.77%), Postives = 88/154 (57.14%), Query Frame = 3
Query: 1134 KYQWEQTSGQQKLNIVDGDKPIAFVNDLKIGSFQFRLTV-WDSDKQAGSDIVTLKVNENQNQKPKATVVESSEVYYLQPDLIKIDGSKSWDDHKIVKYQWIREDDSLAVGDILEKSYSESVXXXXXXXXXXYKFKLIVYDEEGLYDSAITSLQV 1592
K++W+Q G L+++ P+A + +LK+G + F + + ++ S I+ + + ++ N KPKA + V L +++ G S+DD K+++YQWI + + A +IL S +E L+L L PG+YKFKL+V D EGL D +L V
Sbjct: 51 KFKWKQIMGPHNLSVLSDTNPVAVITNLKMGFYVFLVKIDQFNNSSLRSRIIQINIYDSSNIKPKANA-GGNVVVILPRTSVQLSGVNSFDDRKVLRYQWIADVHNPAGLEILGNSVNEPNLILCNLSPGIYKFKLLVEDLEGLQDEDKMTLTV 203 HSP 2 Score: 58.5362 bits (140), Expect = 4.710e-9 Identity = 49/167 (29.34%), Postives = 82/167 (49.10%), Query Frame = 3
Query: 486 SYGEALVFVFVKPGS----TDDDKIVSYHWEIIQGPIVKENIMKDDQPMLQLDKTITQGNYTFKLTV-KDTSGQLNFTIANLIVLPEKDYPPKSDPGPNMILNLPVNSAILNGSGSTDDKKIVSYEW-SKVSDGLTADIQG--VREPILKLSNLQEGTYTFNLKVTD 962
SY L +++ PGS + + K + W+ I GP +++ D P+ + + G Y F + + + + L I + + + PK++ G N+++ LP S L+G S DD+K++ Y+W + V + +I G V EP L L NL G Y F L V D
Sbjct: 28 SYYLPLEKIYLHPGSNLIPSSNAK---FKWKQIMGP-HNLSVLSDTNPV-AVITNLKMGFYVFLVKIDQFNNSSLRSRIIQINIYDSSNIKPKANAGGNVVVILPRTSVQLSGVNSFDDRKVLRYQWIADVHNPAGLEILGNSVNEPNLILCNLSPGIYKFKLLVED 189
BLAST of Dyslexia-associated protein KIAA0319-like protein vs. Planmine SMEST
Match: SMESG000063418.1 (SMESG000063418.1) HSP 1 Score: 74.7146 bits (182), Expect = 3.784e-14 Identity = 52/154 (33.77%), Postives = 88/154 (57.14%), Query Frame = 3
Query: 1134 KYQWEQTSGQQKLNIVDGDKPIAFVNDLKIGSFQFRLTV-WDSDKQAGSDIVTLKVNENQNQKPKATVVESSEVYYLQPDLIKIDGSKSWDDHKIVKYQWIREDDSLAVGDILEKSYSESVXXXXXXXXXXYKFKLIVYDEEGLYDSAITSLQV 1592
K++W+Q G L+++ P+A + +LK+G + F + + ++ S I+ + + ++ N KPKA + V L +++ G S+DD K+++YQWI + + A +IL S +E L+L L PG+YKFKL+V D EGL D +L V
Sbjct: 51 KFKWKQIMGPHNLSVLSDTNPVAVITNLKMGFYVFLVKIDQFNNSSLRSRIIQINIYDSSNIKPKANA-GGNVVVILPRTSVQLSGVNSFDDRKVLRYQWIADVHNPAGLEILGNSVNEPNLILCNLSPGIYKFKLLVEDLEGLQDEDKMTLTV 203 HSP 2 Score: 58.9214 bits (141), Expect = 4.054e-9 Identity = 49/167 (29.34%), Postives = 82/167 (49.10%), Query Frame = 3
Query: 486 SYGEALVFVFVKPGS----TDDDKIVSYHWEIIQGPIVKENIMKDDQPMLQLDKTITQGNYTFKLTV-KDTSGQLNFTIANLIVLPEKDYPPKSDPGPNMILNLPVNSAILNGSGSTDDKKIVSYEW-SKVSDGLTADIQG--VREPILKLSNLQEGTYTFNLKVTD 962
SY L +++ PGS + + K + W+ I GP +++ D P+ + + G Y F + + + + L I + + + PK++ G N+++ LP S L+G S DD+K++ Y+W + V + +I G V EP L L NL G Y F L V D
Sbjct: 28 SYYLPLEKIYLHPGSNLIPSSNAK---FKWKQIMGP-HNLSVLSDTNPVAVI-TNLKMGFYVFLVKIDQFNNSSLRSRIIQINIYDSSNIKPKANAGGNVVVILPRTSVQLSGVNSFDDRKVLRYQWIADVHNPAGLEILGNSVNEPNLILCNLSPGIYKFKLLVED 189
BLAST of Dyslexia-associated protein KIAA0319-like protein vs. Planmine SMEST
Match: SMESG000063418.1 (SMESG000063418.1) HSP 1 Score: 74.3294 bits (181), Expect = 4.255e-14 Identity = 52/154 (33.77%), Postives = 88/154 (57.14%), Query Frame = 3
Query: 1134 KYQWEQTSGQQKLNIVDGDKPIAFVNDLKIGSFQFRLTV-WDSDKQAGSDIVTLKVNENQNQKPKATVVESSEVYYLQPDLIKIDGSKSWDDHKIVKYQWIREDDSLAVGDILEKSYSESVXXXXXXXXXXYKFKLIVYDEEGLYDSAITSLQV 1592
K++W+Q G L+++ P+A + +LK+G + F + + ++ S I+ + + ++ N KPKA + V L +++ G S+DD K+++YQWI + + A +IL S +E L+L L PG+YKFKL+V D EGL D +L V
Sbjct: 51 KFKWKQIMGPHNLSVLSDTNPVAVITNLKMGFYVFLVKIDQFNNSSLRSRIIQINIYDSSNIKPKANA-GGNVVVILPRTSVQLSGVNSFDDRKVLRYQWIADVHNPAGLEILGNSVNEPNLILCNLSPGIYKFKLLVEDLEGLQDEDKMTLTV 203 HSP 2 Score: 58.9214 bits (141), Expect = 4.425e-9 Identity = 49/167 (29.34%), Postives = 82/167 (49.10%), Query Frame = 3
Query: 486 SYGEALVFVFVKPGS----TDDDKIVSYHWEIIQGPIVKENIMKDDQPMLQLDKTITQGNYTFKLTV-KDTSGQLNFTIANLIVLPEKDYPPKSDPGPNMILNLPVNSAILNGSGSTDDKKIVSYEW-SKVSDGLTADIQG--VREPILKLSNLQEGTYTFNLKVTD 962
SY L +++ PGS + + K + W+ I GP +++ D P+ + + G Y F + + + + L I + + + PK++ G N+++ LP S L+G S DD+K++ Y+W + V + +I G V EP L L NL G Y F L V D
Sbjct: 28 SYYLPLEKIYLHPGSNLIPSSNAK---FKWKQIMGP-HNLSVLSDTNPV-AVITNLKMGFYVFLVKIDQFNNSSLRSRIIQINIYDSSNIKPKANAGGNVVVILPRTSVQLSGVNSFDDRKVLRYQWIADVHNPAGLEILGNSVNEPNLILCNLSPGIYKFKLLVED 189 The following BLAST results are available for this feature:
BLAST of Dyslexia-associated protein KIAA0319-like protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of Dyslexia-associated protein KIAA0319-like protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 0
BLAST of Dyslexia-associated protein KIAA0319-like protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 1
BLAST of Dyslexia-associated protein KIAA0319-like protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of Dyslexia-associated protein KIAA0319-like protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of Dyslexia-associated protein KIAA0319-like protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of Dyslexia-associated protein KIAA0319-like protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of Dyslexia-associated protein KIAA0319-like protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Dyslexia-associated protein KIAA0319-like protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of Dyslexia-associated protein KIAA0319-like protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 1
BLAST of Dyslexia-associated protein KIAA0319-like protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 0
BLAST of Dyslexia-associated protein KIAA0319-like protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 1
BLAST of Dyslexia-associated protein KIAA0319-like protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of Dyslexia-associated protein KIAA0319-like protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30028879 ID=SMED30028879|Name=Dyslexia-associated protein KIAA0319-like protein|organism=Schmidtea mediterranea sexual|type=transcript|length=1599bpback to top protein sequence of SMED30028879-orf-1 >SMED30028879-orf-1 ID=SMED30028879-orf-1|Name=SMED30028879-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=458bp MVNVLVTKRLKVNIGKNITIFLPKNSVSLVANVSGNPNQKYDYEWDLVSKback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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