hemicentin-1 isoform X2
Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30028839 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 5
Homology
BLAST of hemicentin-1 isoform X2 vs. Ensembl Human
Match: MXRA5 (matrix remodeling associated 5 [Source:HGNC Symbol;Acc:HGNC:7539]) HSP 1 Score: 107.071 bits (266), Expect = 1.764e-22 Identity = 180/793 (22.70%), Postives = 310/793 (39.09%), Query Frame = 3 Query: 363 LTIHNISSDNSGYYVCRVTLLTTSEHIISLAVVTVKTPPKSISFHFNKSINVFQEQEFIAIQCSVSGGIPPPKISMYIVKDNAIKRLKIISSNFPNSTIAEVSAISLWRPHYLENRGFVMCTAINDAGVLTKNTSLLNIKYKPKIKPFVPNTVNAMINQTIDLSCEVYANPAATIQWVIMQGLQIIDS-------------SKFIAKIRPDMDGPLICEAKNYLGSTKETVQLNVLRDPLIHIDSNYRV----PKNSN------YSINCRVTSNPPPEFIKWYKLSNMTDSSAVLISDDAKL----NFILIDRSST----GMYACVTQNIQISTTGKRKPANSEKTMFLTVTYKPKEPQILGNKIISIMKGEKFIIKCSTDRKSPGEPFPTLKWIDVETKDIVSDMET---------FQVINSES--------RHNGKYKCLAENEIGKSFSRETALVTVNEAPSIITQHKNRKVFLSYSDLPQSISFTCEFRGQPLYEARW-RYGNEKIPPSSQDFKIEDHRNISNERISQIFTKLTIDLYSRTFSQQTSLRSSPNGRYNCEADNRHGIASLDYFLXXXXXXXXXXN-----IRHRKIAASLNQNVVMIRCQAESISTMHIKWYKTNEHIVLPFQSKKYSIFEAEVTKYEPERDLFTPGLKVNELTIKDLENDDFSNYSCVASNDQGIKKVNFEV-VFKSQPDP----PYDLRVTDFEWDSVTINWKPGFNGGLTQNYEILVISENF-----GTQNVPFYSDKNENTLTITGLYPSTPYEIRIYAVNSIGRS 2549 L I + + G Y+C + L + ++ L VTV+ P + ++ H+ + + V+ + IA++C ++ G P P+IS +I D + + +S T+ E +S+ + +RG C A N AG + L P I ++ +I + C A P +++WV+ G QI S + +I + P G C A N +GS + TVQLNV R +N R+ P+ ++ ++C + +P P + M D+ L S D+++ N L+ +S T G Y CV +N K + + + V KP + + + G + C G P P + W + + S M++ + V N+ + R G Y C AEN++GK R V V AP+ I V + Y D+ ++ CE +G+P+ + W N+ IP SS+ + QI+ T+ + Q + RS +G Y C N G ++ + P R+IAA ++ +I C+AE I T + W E +VLP + +T + L I+ L D C+A N+ G ++ ++ V + P P ++T ++++N + T ++ + N G Q FY K + L I+GL R A N+ G + Sbjct: 1913 LVIRKVQVQDRGQYMCTASNLHGLDRMVVLLSVTVQQP-QILASHY-QDVTVYL-GDTIAMEC-LAKGTPAPQIS-WIFPDRRV--WQTVSPVEGRITLHENRTLSIKEASF-SDRGVYKCVASNAAGADSLAIRLHVAALPPVIHQEKLENISLPPGLSIHIHCTAKAAPLPSVRWVLGDGTQIRPSQFLHGNLFVFPNGTLYIRNLAPKDSGRYECVAANLVGSARRTVQLNVQR-----AAANARITGTSPRRTDVRYGGTLKLDCSASGDPWPRILWRLPSKRMIDA---LFSFDSRIKVFANGTLVVKSVTDKDAGDYLCVARN---------KVGDDYVVLKVDVVMKPAKIEHKEENDHKVFYGGDLKVDCVAT----GLPNPEISWSLPDGSLVNSFMQSDDSGGRTKRYVVFNNGTLYFNEVGMREEGDYTCFAENQVGKDEMR--VRVKVVTAPATIRNKTYLAVQVPYGDV---VTVACEAKGEPMPKVTWLSPTNKVIPTSSEKY--------------QIYQDGTLLI-------QKAQRSD-SGNYTCLVRNSAGEDRKTVWIHVNVQPPKINGNPNPITTVREIAAGGSRK--LIDCKAEGIPTPRVLW-AFPEGVVLP-----APYYGNRITVH-----------GNGSLDIRSLRKSDSVQLVCMARNEGGEARLILQLTVLEPMEKPIFHDPISEKITAMAGHTISLN----CSAAGTPTPSLVWVLPNGTDLQSGQQLQRFY-HKADGMLHISGLSSVDAGAYRCVARNAAGHT 2625 HSP 2 Score: 69.707 bits (169), Expect = 4.792e-11 Identity = 158/711 (22.22%), Postives = 261/711 (36.71%), Query Frame = 3 Query: 330 ESQITISHESR-LTIHNISSDNSGYYVCRVTLLTTSEHI-ISLAVVTVKTPPKSISFHFNKSINVFQEQEF-IAIQCSVSGGIPPPKISMYIVKDNAIKRLKIISSN---FPNSTIAEVSAISLWRPHYLEN-----RGFVMCTAINDAGVLTKNTSLLNIKYKP---KIKPFVPNTVNAMINQTIDLSCEVYANPAATIQWVIMQG------------LQIIDSSKFIAKIRPDMD-GPLICEAKNYLGSTKETVQLNVLRDP--LIHIDSN-YRVPKNSNYSINCRVTSNPPPEFIKWYKLSNMTDSSAV---LISDDAK-------------LNFILIDRSSTGMYACVTQNIQISTTGKRKPANSEKTMFLTVTYKPKEPQILGNKI---ISIMKGEKFIIKCSTDRKSPGEPFPTLKWIDVETKDIVSDMETFQVIN--------SESRHNGKYKCLAENEIGKSFSRETALVTVNEAPSIITQHKN-----RKVFLSYSDLPQSISFTCEFRGQPLYEARWRYGNEKIPPSS-QDFKIEDHRNISNERISQIFTKLTIDLYSRTFSQQTSLRSSPNGRYNCEADNRHGIASLDYFLXXXXXXXXXXNIRHRKIA---ASLNQNVVMIRCQAESISTMHIKWYKTNEHIVLPFQSKKYSIFEAEVTKYEPERDLFTPGLKVNELTIKDLENDDFSNYSCVASNDQG 2264 E +IT+ HE+R L+I S + G Y C + ++ + I L V + PP H K N+ I I C+ P P + + I+ + + N FPN T+ Y+ N G C A N G + T LN++ +I P + T+ L C +P I W + +++ + + K D D G +C A+N +G ++++V+ P + H + N ++V + ++C T P PE I W ++ D S V + SDD+ L F + G Y C +N GK + + VT P + NK + + G+ + C ++ GEP P + W+ K I + E +Q+ ++ +G Y CL N G+ R+T + VN P I + N R++ S C+ G P W + + P+ +I H N S +D+ SLR S + + C A N G A L L + ++ I H I+ ++ + + + C A T + W VLP + S ++ ++ + D G+ L I L + D Y CVA N G Sbjct: 1999 EGRITL-HENRTLSIKEASFSDRGVYKCVASNAAGADSLAIRLHVAAL--PP---VIHQEKLENISLPPGLSIHIHCTAKAA-PLPSVRWVLGDGTQIRPSQFLHGNLFVFPNGTL------------YIRNLAPKDSGRYECVAANLVGS-ARRTVQLNVQRAAANARITGTSPRRTDVRYGGTLKLDCSASGDPWPRILWRLPSKRMIDALFSFDSRIKVFANGTLVVKSVTDKDAGDYLCVARNKVGDDYVVLKVDVVMKPAKIEHKEENDHKVFYGGDLKVDCVATGLPNPE-ISW----SLPDGSLVNSFMQSDDSGGRTKRYVVFNNGTLYFNEVGMREEGDYTCFAEN----QVGK----DEMRVRVKVVT----APATIRNKTYLAVQVPYGDVVTVAC----EAKGEPMPKVTWLSPTNKVIPTSSEKYQIYQDGTLLIQKAQRSDSGNYTCLVRNSAGE--DRKTVWIHVNVQPPKINGNPNPITTVREIAAGGS----RKLIDCKAEGIPTPRVLWAFPEGVVLPAPYYGNRITVHGNGS------------LDIR--------SLRKSDSVQLVCMARNEGGEARL--ILQLTVLEPMEKPIFHDPISEKITAMAGHTISLNCSAAGTPTPSLVW-------VLPNGTDLQS--GQQLQRFYHKAD----GM----LHISGLSSVDAGAYRCVARNAAG 2623 HSP 3 Score: 53.1434 bits (126), Expect = 4.655e-6 Identity = 111/560 (19.82%), Postives = 201/560 (35.89%), Query Frame = 3 Query: 774 NIKYKPKIKPFVPNTVNAMINQTIDLSCEVYANPAATIQWVI------------MQGLQIIDSSKF-IAKIRPDMDGPLICEAKNYLGSTKETVQLNV-LRDPLIHIDSNYR---VPKNSNYSINCRVTSNPPPEFI-------KWYKLSNMTDSSAVLISDDAKLNFILIDRSSTGMYACVTQNIQISTTGKRKPANSEKTMFLTVTYKPKEPQILGNKI--ISIMKGEKFIIKCSTDRKSPGEPFPTLKWIDVETKDI-----------VSDMETFQVINSESRHNGKYKCLAENEIGKSFSRETALVTVNEAP--SIITQHKNRKVFLSYSDLPQSISFTCEFRGQPLYEARWRYGNEKIPPSSQDFKIEDHRNISNERISQIFTKLTIDLYSRTFSQQTSLRSSPNGRYNCEADNRHGIASLDYFLXXXXXXXXXXNIRHRK--IAASLNQNVVMIRCQAESISTMHIKWYKTNEHIVLPF--------QSKKYSIFEAEVTKYEPERDLFTPGLKVNELTIKDLENDDFSNYSCVASNDQGIKKVNFEVVFKSQP 2306 ++ KP+I P TV+ CE P + W +Q +++ + I K++ G +C A N G + V L+V ++ P I + S+Y+ V ++ C P P+ W +S + + + ++ L+ S G+Y CV N A ++ + + P I K+ IS+ G I C+ P P+++W+ + I V T + N + +G+Y+C+A N +G +R T + V A + IT R+ + Y ++ C G P WR ++++ + F + RI ++F T+ + S T G Y C A N+ G DY ++ + I H++ + + C A + I W + +V F ++K+Y +F L NE+ +++ E D Y+C A N G ++ V + P Sbjct: 1848 SLGEKPQILTKSPQTVSVTAETDTVFPCEATGKPKPFVTWTKVSTGALMTPNTRIQRFEVLKNGTLVIRKVQVQDRGQYMCTASNLHGLDRMVVLLSVTVQQPQI-LASHYQDVTVYLGDTIAMECLAKGTPAPQISWIFPDRRVWQTVSPV--EGRITLHENRTLSIKEASFSDRGVYKCVASN-----------AAGADSLAIRLHVAALPPVIHQEKLENISLPPGLSIHIHCTAK----AAPLPSVRWVLGDGTQIRPSQFLHGNLFVFPNGTLYIRNLAPKDSGRYECVAANLVGS--ARRTVQLNVQRAAANARITGTSPRRTDVRYGG---TLKLDCSASGDPWPRILWRLPSKRMIDALFSF---------DSRI-KVFANGTLVVKSVTDKDA--------GDYLCVARNKVGD---DYVVLKVDVVMKPAKIEHKEENDHKVFYGGDLKVDCVATGLPNPEISWSLPDGSLVNSFMQSDDSGGRTKRYVVFNNGT-------------LYFNEVGMRE-EGD----YTCFAENQVGKDEMRVRVKVVTAP 2345
BLAST of hemicentin-1 isoform X2 vs. Ensembl Human
Match: ROBO2 (roundabout guidance receptor 2 [Source:HGNC Symbol;Acc:HGNC:10250]) HSP 1 Score: 106.686 bits (265), Expect = 2.084e-22 Identity = 146/630 (23.17%), Postives = 238/630 (37.78%), Query Frame = 3 Query: 810 PNTVNAMINQTIDLSCEVYANPAATIQWVI-------------MQGLQIIDSSKFIAKI------RPDMDGPLICEAKNYLG---STKETVQLNVLRDPLIHIDSNYRVPKNSNYSINCRVTSNPPPEFIKWYKLSNMTDSSAVLIS-DDAKLNFILIDRSSTGMYACVTQNIQISTTGKRKPANSEKTMFLTVTYKPKEPQILGNKIISIMKGEKFI-IKCSTDRKSPGEPFPTLKWIDVETKDI------VSDMETFQVINSESRHNGKYKCLAENEIGKSFSRETALVTVNEAPSIITQHKNRKVFLSYSDLPQSISFTCEFRGQPLYEARWRYGNEKIPPSSQDFKIEDHRNISNERISQIFTK-LTIDLYSRTFSQQTSLRSSPNGRYNCEADNRHG--IASLDYFLXXXXXXXXXXNIRHRKIAASLN-QNVVMIRCQAESISTMHIKWYKTNEHIVLPFQSKKYSIFEAEVTKYEPERDLFTPGLKVNELTIKDLENDDFSNYSCVASNDQGIKKVNFEVV---------------FKSQPDPPYDLRVTDFEWDSVTINWKPGFNGGLTQN-YEILVISENFGTQNVPFYSDKNENTLTITGLYPSTPYEIRIYAVNSIGRS 2549 P+ V + L+C+ P TI+W + + S F +I +PD +G +C A+NYLG S ++++ +LRD ++ V + C+ P I W K D IS KL +S GMY CV N+ G+R +E T+F + P L I ++ E+ + +C G+P PT++W + D+ + D T ++ + S G Y C+AEN +GK +A +TV P + + +++ V ++++F CE +G P W+ SQ+ + N R S T LTI T+++ S G Y C+A G +A + I +L +++C+A I W K E P + + +I E L IK+L D Y+CVA++ G + ++ V P PP +VTD +SVT++W+PG G L + Y I S++ + T+ GL P+T Y + A+N G S Sbjct: 37 PSDVIVSKGEPTTLNCKAEGRPTPTIEWYKDGERVETDKDDPRSHRMLLPSGSLFFLRIVHGRRSKPD-EGSYVCVARNYLGEAVSRNASLEVALLRDDFRQNPTDVVVAAGEPAILECQPPRGHPEPTIYWKKDKVRIDDKEERISIRGGKLMISNTRKSDAGMYTCVGTNM----VGERDSDPAELTVF-------ERPTFLRRPINQVVLEEEAVEFRCQVQ----GDPQPTVRW-KKDDADLPRGRYDIKDDYTLRIKKTMSTDEGTYMCIAENRVGK--MEASATLTVRAPPQFVVRPRDQIVAQG-----RTVTFPCETKGNPQPAVFWQKEG------SQNLLFPNQPQQPNSRCSVSPTGDLTI----------TNIQRSDAGYYICQALTVAGSILAKAQLEVTDVLTDRPPPIILQGPANQTLAVDGTALLKCKATGDPLPVISWLK--EGFTFPGRDPRATIQEQ------------------GTLQIKNLRISDTGTYTCVATSSSG--ETSWSAVLDVTESGATISKNYDLSDLPGPPSKPQVTDVTKNSVTLSWQPGTPGTLPASAYIIEAFSQSVSNSWQTVANHVKTTLYTVRGLRPNTIYLFMVRAINPQGLS 604 HSP 2 Score: 62.3882 bits (150), Expect = 6.201e-9 Identity = 101/467 (21.63%), Postives = 172/467 (36.83%), Query Frame = 3 Query: 360 RLTIHNISSDNSGYYVC--RVTLLTTSEHIISLAVVTVKTPPKSISFHFNKSINVFQEQEFIAIQCSVSGGIPPPKISMYIVK---DNAIKRLKIISSNFPNSTIAEVSAISLWRPHYLENRGFVMCTAINDAGVLTKNTSLLNIKYKPKIKPFVPNTVNAMI--NQTIDLSCEVYANPAATIQWV-----IMQGLQII--DSSKFIAKIRPDMDGPLICEAKNYLGSTKETVQLNVLRDPLIHIDSNYR-VPKNSNYSINCRVTSNPPPEFIKWYKLSNMT---------DSSAVLISDDAKLNFILIDRSSTGMYACVTQNIQISTTGKRKPANSEKTMFLTVTYKPKEPQILGNKIISIMKGEKFIIKCSTDRKSPGEPFPTLKWI-------DVETKDIVSDMETFQVINSESRHNGKYKCLAENEIGKSFSRETALVTVNEAPSIITQHKNRKVFLSYSDLP 1667 R+ S + G YVC R L SL V ++ F N + V E ++C G P P I K D+ +R+ I S + A G C N G + + L + +P F+ +N ++ + ++ C+V +P T++W + +G I D + I K +G +C A+N +G + + L V P + + V + + C NP P W K + +S +S L I RS G Y C + S K A E T LT P Q N+ +++ ++KC K+ G+P P + W+ + + + + T Q+ N G Y C+A + G+ + +A++ V E+ + I+++ + SDLP Sbjct: 94 RIVHGRRSKPDEGSYVCVARNYLGEAVSRNASLEVALLRD-----DFRQNPTDVVVAAGEPAILECQPPRGHPEPTIYWKKDKVRIDDKEERISIRGGKLMISNTRKSDA------------GMYTCVGTNMVGERDSDPAELTVFERPT---FLRRPINQVVLEEEAVEFRCQVQGDPQPTVRWKKDDADLPRGRYDIKDDYTLRIKKTMSTDEGTYMCIAENRVGKMEASATLTVRAPPQFVVRPRDQIVAQGRTVTFPCETKGNPQPAVF-WQKEGSQNLLFPNQPQQPNSRCSVSPTGDLTITNIQRSDAGYYICQALTVAGSILAK---AQLEVTDVLTDRPPPIILQGPANQTLAV--DGTALLKC----KATGDPLPVISWLKEGFTFPGRDPRATIQEQGTLQIKNLRISDTGTYTCVATSSSGE--TSWSAVLDVTESGATISKNYD------LSDLP 522
BLAST of hemicentin-1 isoform X2 vs. Ensembl Human
Match: ROBO2 (roundabout guidance receptor 2 [Source:HGNC Symbol;Acc:HGNC:10250]) HSP 1 Score: 105.916 bits (263), Expect = 3.069e-22 Identity = 146/630 (23.17%), Postives = 238/630 (37.78%), Query Frame = 3 Query: 810 PNTVNAMINQTIDLSCEVYANPAATIQWVI-------------MQGLQIIDSSKFIAKI------RPDMDGPLICEAKNYLG---STKETVQLNVLRDPLIHIDSNYRVPKNSNYSINCRVTSNPPPEFIKWYKLSNMTDSSAVLIS-DDAKLNFILIDRSSTGMYACVTQNIQISTTGKRKPANSEKTMFLTVTYKPKEPQILGNKIISIMKGEKFI-IKCSTDRKSPGEPFPTLKWIDVETKDI------VSDMETFQVINSESRHNGKYKCLAENEIGKSFSRETALVTVNEAPSIITQHKNRKVFLSYSDLPQSISFTCEFRGQPLYEARWRYGNEKIPPSSQDFKIEDHRNISNERISQIFTK-LTIDLYSRTFSQQTSLRSSPNGRYNCEADNRHG--IASLDYFLXXXXXXXXXXNIRHRKIAASLN-QNVVMIRCQAESISTMHIKWYKTNEHIVLPFQSKKYSIFEAEVTKYEPERDLFTPGLKVNELTIKDLENDDFSNYSCVASNDQGIKKVNFEVV---------------FKSQPDPPYDLRVTDFEWDSVTINWKPGFNGGLTQN-YEILVISENFGTQNVPFYSDKNENTLTITGLYPSTPYEIRIYAVNSIGRS 2549 P+ V + L+C+ P TI+W + + S F +I +PD +G +C A+NYLG S ++++ +LRD ++ V + C+ P I W K D IS KL +S GMY CV N+ G+R +E T+F + P L I ++ E+ + +C G+P PT++W + D+ + D T ++ + S G Y C+AEN +GK +A +TV P + + +++ V ++++F CE +G P W+ SQ+ + N R S T LTI T+++ S G Y C+A G +A + I +L +++C+A I W K E P + + +I E L IK+L D Y+CVA++ G + ++ V P PP +VTD +SVT++W+PG G L + Y I S++ + T+ GL P+T Y + A+N G S Sbjct: 53 PSDVIVSKGEPTTLNCKAEGRPTPTIEWYKDGERVETDKDDPRSHRMLLPSGSLFFLRIVHGRRSKPD-EGSYVCVARNYLGEAVSRNASLEVALLRDDFRQNPTDVVVAAGEPAILECQPPRGHPEPTIYWKKDKVRIDDKEERISIRGGKLMISNTRKSDAGMYTCVGTNM----VGERDSDPAELTVF-------ERPTFLRRPINQVVLEEEAVEFRCQVQ----GDPQPTVRW-KKDDADLPRGRYDIKDDYTLRIKKTMSTDEGTYMCIAENRVGK--MEASATLTVRAPPQFVVRPRDQIVAQG-----RTVTFPCETKGNPQPAVFWQKEG------SQNLLFPNQPQQPNSRCSVSPTGDLTI----------TNIQRSDAGYYICQALTVAGSILAKAQLEVTDVLTDRPPPIILQGPANQTLAVDGTALLKCKATGDPLPVISWLK--EGFTFPGRDPRATIQEQ------------------GTLQIKNLRISDTGTYTCVATSSSG--ETSWSAVLDVTESGATISKNYDLSDLPGPPSKPQVTDVTKNSVTLSWQPGTPGTLPASAYIIEAFSQSVSNSWQTVANHVKTTLYTVRGLRPNTIYLFMVRAINPQGLS 620 HSP 2 Score: 62.3882 bits (150), Expect = 6.596e-9 Identity = 103/474 (21.73%), Postives = 175/474 (36.92%), Query Frame = 3 Query: 360 RLTIHNISSDNSGYYVC--RVTLLTTSEHIISLAVVTVKTPPKSISFHFNKSINVFQEQEFIAIQCSVSGGIPPPKISMYIVKDN----------AIKRLKIISSNFPNSTIAEVSAISLWRPHYLENRGFVMCTAINDAGVLTKNTSLLNIKYKPKIKPFVPNTVNAMI--NQTIDLSCEVYANPAATIQWV-----IMQGLQII--DSSKFIAKIRPDMDGPLICEAKNYLGSTKETVQLNVLRDPLIHIDSNYR-VPKNSNYSINCRVTSNPPPEFIKWYKLSNMT---------DSSAVLISDDAKLNFILIDRSSTGMYACVTQNIQISTTGKRKPANSEKTMFLTVTYKPKEPQILGNKIISIMKGEKFIIKCSTDRKSPGEPFPTLKWI-------DVETKDIVSDMETFQVINSESRHNGKYKCLAENEIGKSFSRETALVTVNEAPSIITQHKNRKVFLSYSDLP 1667 R+ S + G YVC R L SL V ++ F N + V E ++C G P P I Y KD +I+ K++ SN S + G C N G + + L + +P F+ +N ++ + ++ C+V +P T++W + +G I D + I K +G +C A+N +G + + L V P + + V + + C NP P W K + +S +S L I RS G Y C + S K A E T LT P Q N+ +++ ++KC K+ G+P P + W+ + + + + T Q+ N G Y C+A + G+ + +A++ V E+ + I+++ + SDLP Sbjct: 110 RIVHGRRSKPDEGSYVCVARNYLGEAVSRNASLEVALLRD-----DFRQNPTDVVVAAGEPAILECQPPRGHPEPTI--YWKKDKVRIDDKEERISIRGGKLMISNTRKS-----------------DAGMYTCVGTNMVGERDSDPAELTVFERPT---FLRRPINQVVLEEEAVEFRCQVQGDPQPTVRWKKDDADLPRGRYDIKDDYTLRIKKTMSTDEGTYMCIAENRVGKMEASATLTVRAPPQFVVRPRDQIVAQGRTVTFPCETKGNPQPAVF-WQKEGSQNLLFPNQPQQPNSRCSVSPTGDLTITNIQRSDAGYYICQALTVAGSILAK---AQLEVTDVLTDRPPPIILQGPANQTLAV--DGTALLKC----KATGDPLPVISWLKEGFTFPGRDPRATIQEQGTLQIKNLRISDTGTYTCVATSSSGE--TSWSAVLDVTESGATISKNYD------LSDLP 538
BLAST of hemicentin-1 isoform X2 vs. Ensembl Human
Match: ROBO2 (roundabout guidance receptor 2 [Source:HGNC Symbol;Acc:HGNC:10250]) HSP 1 Score: 105.916 bits (263), Expect = 3.170e-22 Identity = 146/630 (23.17%), Postives = 238/630 (37.78%), Query Frame = 3 Query: 810 PNTVNAMINQTIDLSCEVYANPAATIQWVI-------------MQGLQIIDSSKFIAKI------RPDMDGPLICEAKNYLG---STKETVQLNVLRDPLIHIDSNYRVPKNSNYSINCRVTSNPPPEFIKWYKLSNMTDSSAVLIS-DDAKLNFILIDRSSTGMYACVTQNIQISTTGKRKPANSEKTMFLTVTYKPKEPQILGNKIISIMKGEKFI-IKCSTDRKSPGEPFPTLKWIDVETKDI------VSDMETFQVINSESRHNGKYKCLAENEIGKSFSRETALVTVNEAPSIITQHKNRKVFLSYSDLPQSISFTCEFRGQPLYEARWRYGNEKIPPSSQDFKIEDHRNISNERISQIFTK-LTIDLYSRTFSQQTSLRSSPNGRYNCEADNRHG--IASLDYFLXXXXXXXXXXNIRHRKIAASLN-QNVVMIRCQAESISTMHIKWYKTNEHIVLPFQSKKYSIFEAEVTKYEPERDLFTPGLKVNELTIKDLENDDFSNYSCVASNDQGIKKVNFEVV---------------FKSQPDPPYDLRVTDFEWDSVTINWKPGFNGGLTQN-YEILVISENFGTQNVPFYSDKNENTLTITGLYPSTPYEIRIYAVNSIGRS 2549 P+ V + L+C+ P TI+W + + S F +I +PD +G +C A+NYLG S ++++ +LRD ++ V + C+ P I W K D IS KL +S GMY CV N+ G+R +E T+F + P L I ++ E+ + +C G+P PT++W + D+ + D T ++ + S G Y C+AEN +GK +A +TV P + + +++ V ++++F CE +G P W+ SQ+ + N R S T LTI T+++ S G Y C+A G +A + I +L +++C+A I W K E P + + +I E L IK+L D Y+CVA++ G + ++ V P PP +VTD +SVT++W+PG G L + Y I S++ + T+ GL P+T Y + A+N G S Sbjct: 37 PSDVIVSKGEPTTLNCKAEGRPTPTIEWYKDGERVETDKDDPRSHRMLLPSGSLFFLRIVHGRRSKPD-EGSYVCVARNYLGEAVSRNASLEVALLRDDFRQNPTDVVVAAGEPAILECQPPRGHPEPTIYWKKDKVRIDDKEERISIRGGKLMISNTRKSDAGMYTCVGTNM----VGERDSDPAELTVF-------ERPTFLRRPINQVVLEEEAVEFRCQVQ----GDPQPTVRW-KKDDADLPRGRYDIKDDYTLRIKKTMSTDEGTYMCIAENRVGK--MEASATLTVRAPPQFVVRPRDQIVAQG-----RTVTFPCETKGNPQPAVFWQK------EGSQNLLFPNQPQQPNSRCSVSPTGDLTI----------TNIQRSDAGYYICQALTVAGSILAKAQLEVTDVLTDRPPPIILQGPANQTLAVDGTALLKCKATGDPLPVISWLK--EGFTFPGRDPRATIQEQ------------------GTLQIKNLRISDTGTYTCVATSSSG--ETSWSAVLDVTESGATISKNYDLSDLPGPPSKPQVTDVTKNSVTLSWQPGTPGTLPASAYIIEAFSQSVSNSWQTVANHVKTTLYTVRGLRPNTIYLFMVRAINPQGLS 604 HSP 2 Score: 62.003 bits (149), Expect = 7.350e-9 Identity = 103/474 (21.73%), Postives = 175/474 (36.92%), Query Frame = 3 Query: 360 RLTIHNISSDNSGYYVC--RVTLLTTSEHIISLAVVTVKTPPKSISFHFNKSINVFQEQEFIAIQCSVSGGIPPPKISMYIVKDN----------AIKRLKIISSNFPNSTIAEVSAISLWRPHYLENRGFVMCTAINDAGVLTKNTSLLNIKYKPKIKPFVPNTVNAMI--NQTIDLSCEVYANPAATIQWV-----IMQGLQII--DSSKFIAKIRPDMDGPLICEAKNYLGSTKETVQLNVLRDPLIHIDSNYR-VPKNSNYSINCRVTSNPPPEFIKWYKLSNMT---------DSSAVLISDDAKLNFILIDRSSTGMYACVTQNIQISTTGKRKPANSEKTMFLTVTYKPKEPQILGNKIISIMKGEKFIIKCSTDRKSPGEPFPTLKWI-------DVETKDIVSDMETFQVINSESRHNGKYKCLAENEIGKSFSRETALVTVNEAPSIITQHKNRKVFLSYSDLP 1667 R+ S + G YVC R L SL V ++ F N + V E ++C G P P I Y KD +I+ K++ SN S + G C N G + + L + +P F+ +N ++ + ++ C+V +P T++W + +G I D + I K +G +C A+N +G + + L V P + + V + + C NP P W K + +S +S L I RS G Y C + S K A E T LT P Q N+ +++ ++KC K+ G+P P + W+ + + + + T Q+ N G Y C+A + G+ + +A++ V E+ + I+++ + SDLP Sbjct: 94 RIVHGRRSKPDEGSYVCVARNYLGEAVSRNASLEVALLRD-----DFRQNPTDVVVAAGEPAILECQPPRGHPEPTI--YWKKDKVRIDDKEERISIRGGKLMISNTRKS-----------------DAGMYTCVGTNMVGERDSDPAELTVFERPT---FLRRPINQVVLEEEAVEFRCQVQGDPQPTVRWKKDDADLPRGRYDIKDDYTLRIKKTMSTDEGTYMCIAENRVGKMEASATLTVRAPPQFVVRPRDQIVAQGRTVTFPCETKGNPQPAVF-WQKEGSQNLLFPNQPQQPNSRCSVSPTGDLTITNIQRSDAGYYICQALTVAGSILAK---AQLEVTDVLTDRPPPIILQGPANQTLAV--DGTALLKC----KATGDPLPVISWLKEGFTFPGRDPRATIQEQGTLQIKNLRISDTGTYTCVATSSSGE--TSWSAVLDVTESGATISKNYD------LSDLP 522
BLAST of hemicentin-1 isoform X2 vs. Ensembl Human
Match: ROBO1 (roundabout guidance receptor 1 [Source:HGNC Symbol;Acc:HGNC:10249]) HSP 1 Score: 105.145 bits (261), Expect = 5.265e-22 Identity = 157/666 (23.57%), Postives = 264/666 (39.64%), Query Frame = 3 Query: 705 NRGFVMCTAINDAGVLTKNTSLLNIK-YKPKIKPFVPNTVNAMINQTIDLSCEVYANPAATIQWVIMQGLQIIDSSK---------------FIAKI------RPDMDGPLICEAKNYLG---STKETVQLNVLRDPLIHIDSNYRVPKNSNYSINCRVTSNPPPEFIKWYK-LSNMTDSSAVLISDDAKLNFILIDRSSTGMYACVTQNIQISTTGKRKPANSEKTMFLTVTYKPKEPQILGNKIISIMKGEKFIIKCSTDRKSPGEPFPTLKWI--DVE---TKDIVSDMETFQVINSESRHNGKYKCLAENEIGKSFSRETALVTVNEAPSIITQHKNRKVFLSYSDLPQSISFTCEFRGQPLYEARWRY-GNEKIPPSSQDFKIEDHRNISNERISQIFTKLTIDLYSRTFSQQTSLRSSPNGRYNCEADNRHGIASLDYFLXXXXXXXXXXNIRHRKIAASLNQNVV-----MIRCQAESISTMHIKWYKTNEHIVLPFQSKKYSIFEAEVTKYEPERDLFTPGLKVNELTIKDLENDDFSNYSCVASNDQG-------IKKVNFEVVFKSQ--------PDPPYDLRVTDFEWDSVTINWKPGFNGGLT-QNYEILVISENFGTQNVPFYSDKNENTLTITGLYPSTPYEIRIYAVNSIG 2543 + G + T+ ND L S L + + P+I P+ + + L+C+ P TI+W +G + +++ K F +I RPD +G +C A+NYLG S ++++ +LRD S+ V + C+ P I W K S + D + KL +S G Y CV N+ G+R+ +E LTV +P + N +++ +F KC ++ G+P PT++W D E ++ + D T ++ + G Y C+AEN +GK + +A +TV E P + + +++ V L ++++F CE G P WR G++ + F + ++ S +SQ LTI T+++ S G Y C+ N G +L + + R+ +NQ V ++ C A I W K + +++ Q + E V L I+ + D Y+C+AS G I+ F V + P P VTD ++VT++W+P N G T +Y I S G+ + T I GL P+ Y + A N+ G Sbjct: 39 DHGTPIPTSDNDDNSLGYTGSRLRQEDFPPRIVEH-PSDLIVSKGEPATLNCKAEGRPTPTIEW--YKGGERVETDKDDPRSHRMLLPSGSLFFLRIVHGRKSRPD-EGVYVCVARNYLGEAVSHNASLEVAILRDDFRQNPSDVMVAVGEPAVMECQPPRGHPEPTISWKKDGSPLDDKDERITIRGGKLMITYTRKSDAGKYVCVGTNM----VGERESEVAE----LTVLERPSFVKRPSNLAVTVDDSAEF--KC----EARGDPVPTVRWRKDDGELPKSRYEIRDDHTLKIRKVTAGDMGSYTCVAENMVGK--AEASATLTVQEPPHFVVKPRDQVVALG-----RTVTFQCEATGNPQPAIFWRREGSQNL-----LFSYQPPQSSSRFSVSQT-GDLTI----------TNVQRSDVGYYICQTLNVAGSIITKAYLEVTDVIADRPPPVIRQ--GPVNQTVAVDGTFVLSCVATGSPVPTILWRK--DGVLVSTQDSRIKQLENGV------------------LQIRYAKLGDTGRYTCIASTPSGEATWSAYIEVQEFGVPVQPPRPTDPNLIPSAPSKPEVTDVSRNTVTLSWQPNLNSGATPTSYIIEAFSHASGSSWQTVAENVKTETSAIKGLKPNAIYLFLVRAANAYG 641
BLAST of hemicentin-1 isoform X2 vs. Ensembl Celegans
Match: igcm-1 (ImmunoGlobulin-like Cell adhesion Molecule family [Source:UniProtKB/TrEMBL;Acc:Q9TXI8]) HSP 1 Score: 129.028 bits (323), Expect = 8.007e-30 Identity = 178/764 (23.30%), Postives = 297/764 (38.87%), Query Frame = 3 Query: 396 GYYVCRVTLLTTSE-HIISLAVVTVKTPPKSISFHFNKSINVFQEQEFIAIQCSVSGGIPPPKISMYIVKDNAIKRLKIISSNFPNSTIAEVSAISLWRPHYLENRGFVMCTAINDA--GVLTKN--TSLLNIKYKPKIKPFVPNTVNAM-----INQTIDLSCEVYANPAA-TIQWVIMQGLQIIDSSKFIAKIRP-----DMDGPLICEAKNYLGSTKETVQLNVLRDPLIHIDSNYRVPKNSNYSINCRVTSNPPPEFIKWYKLSNMTDSSAVLISDDAKLNFILIDRSSTGMYACVTQN-IQISTTGKRKPANSEKTMFLTVTYKPKEPQILGNKIISIMKGEKFIIKCSTDRKSPGEPFPTLKWIDVETKDIVS----DMETFQVINSESRHNGKYKCLAENEIGKSFSRETALVTVNEAPSIITQHKNRKVFLSYSDLPQSISFTCEFRGQPLYEARWRYGNEKIPPSSQDFKIEDHRNISNER-ISQIFTKLTIDLYSRTFSQQTSLRSSPNGRYNCEADNRHGIASLDYFLXXXXXXXXXXNIRHRK-----IAASLNQNVVMIRCQAESISTMHIKWYKTNEHIVLPFQSKKYSIFEAEVTKYEPERDLFTPGLKVNELTIKDLENDDFSNYSCVASNDQGIKKVNFEVVFKSQPDPPYDLRVTDFEWDSVTINWKPGFNGGLTQNY--EILVISENFGT--QNVP--------FYSDK-------NENTLTITGLYPSTPYEIRIYAVNSIGRS 2549 G Y C V S+ +LA V V PP S +V E +F+ +C GG P P + + + ++ I I ++ F + ++ +R ++ V C N A G TK +S LN+ YKP + FV T N + ++L+C +NP A + +W I ++ KI P M G C + N LG +++ V P I++ + + + I C V++ P IKW + + ++L I ++ +G Y C+ N + + + T + V KP + QI+ + ++ GE + C + G P + W + I ++F+V N++ NG Y C A N++G+ T ++TV E I + ++F S Q CE +G P +W + S I S + + + F T+ + T + L+ S G + C ADN D + K +RK +AA+ + +IRC+ + W + I +++++S +T E + L I+ ++ D+ Y C A+N G V E+ S P P DL+ +SV + W P F+GG Q Y E I G N P D+ ++N TGL P + Y +RI AV+ G S Sbjct: 115 GTYHCNVIGTDDSDVQYSALATVVVLVPPGDPIISTTPSESVI-EGDFMTAKCVSVGGSPQPTFT-WTLPNDTIASSAIFTTQFRD---GATESLLHFRVTSSDDGKSVQCDVTNRAMLGGETKQVKSSQLNVLYKPVV--FVTPTENLTHLSVEEGELVNLTCNSASNPPAHSYEW-----KHIASGERYQGKIWPIRVDSSMSGDFECRSTNELGEGTAVLKMVVQHIPRINVPESISPNEMEDIDILCEVSAVPEVIDIKWVGPNGFKQ-------NGSRLTITSISKAQSGNYTCMATNFLTVYGHSGSQQRMGTGTTIVDVKRKPGQAQIVSARQ-NVDVGETIKLMCQAE--DAGNPSASYTWASPSSGGIFGLEGHTEKSFEVRNAQLSDNGVYSCKAYNDLGEG-KIGTVMITVIEKARISSPLATERIFTSGE---QGKILECEAQGYPSPVIKWLKDGRPVKQS-----IYASSATSESKCLPEDFCTQTV---ASTLTLAGPLKWSDKGNFTCVADNGSDKTDKDSSSWTIVRVLHKPVFLNRKFPEKSLAAADIGSQAIIRCKVSARPEPEFHWMFRDSEIS---ENERHSFHTVGITGKPDEYEQL--------LQIESVQESDYGEYVCRATNGNGGDHVVIELRKTSPPALPLDLQKLSATSNSVLLGWVPQFDGGADQTYVLETRKIDPFTGEIDGNAPVSKLNINAVQQDQEIDGTLVSKNIFNFTGLTPLSTYNLRIQAVSEKGES 833
BLAST of hemicentin-1 isoform X2 vs. Ensembl Celegans
Match: him-4 (High Incidence of Males (Increased X chromosome loss) [Source:UniProtKB/TrEMBL;Acc:A4UVK0]) HSP 1 Score: 104.375 bits (259), Expect = 4.599e-22 Identity = 157/706 (22.24%), Postives = 278/706 (39.38%), Query Frame = 3 Query: 306 KPCVVPDSESQIT-ISHESRLTIHNISSDNSGYYVCRVTLLTTSEHIISLAVVTVKTPPKSISFHFNKSINVFQEQEFIAIQCSVSGGIPPPKISMYIVKDNAIKRLKIISSNFPNSTIAEVSAISLWRPHYLE-NRGFVMCTAINDAGVLTKNTSLLNIKYKPKI-KPFVPNTVNAMINQTIDLSCEVYANPAATIQWVIMQGLQIIDSSKFIA-----------KIRPDMDGPLICEAKNYLGSTKETVQLNVLRDPLI---HIDSNYRVPKNSNYSINCRVTSNPPPEFIKWYKLSNMTDSSAVLISDDA--KLNFILIDRSSTGMYACVTQNIQISTTGKRKPANSEKTMFLTVTYKPKEPQILGNKIISIMKGEKFIIKCSTDRKSPGEPFPTLKWIDVE-TKD----------------IVSDMETFQVINSESRHNGKYKCLAENEIGKSFSRETALVTVNEAPSIITQ--HKNRKVFLSYSDLPQSISFTCEFRGQPLYEARWRYGNEKIPPSSQDFKIEDHRNISNERISQIFTKLTIDLYSRTFSQQTSLRSSPNGRYNCEADNRHGIASLDYFLXXXXXXXXXXNIRHRKIAASLNQNVVMIRCQAE-SISTMHIKWYKTNEHIVLPFQSKKYSIFEAEVTKYEPERDLFTPGLKVNELTIKDLENDDFSNYSCVASNDQGIKKVNFEVVFKSQP 2306 +P + +++IT +S++ RLTI N++ ++ G Y CRV A V V PP I +K+ E + + C +G P P I+ + KD ++ I+ PN E++ L E + G C A N AG + ++ ++ N+ PKI K +P+ + N+ + +SC VYA P A I W ++ + + S KF+ K+R C A N G+ K ++++L P +I V + +++C +P P I W K N + + + DA +L + S G Y C+ N + G N+ + + P I G + ++ E F + D S G +DVE KD I S + +++ +G+Y C+ N G+ +R+ VN+ PSI + N + + Y + C G P + W + ++ + P S +++ ++ SQ+ G Y CEA N G A D+ + + PP + + R+ + + +++ C AE S+ + W+ +E + + KY+ E L + +++ DD Y C A N+ GI K F+++ P Sbjct: 2231 QPIDLEAEDARITRLSNDRRLTILNVTENDEGQYSCRVKNDAGENSFDFKATVLV--PPTIIMLDKDKNKTAV-EHSTVTLSCPATGK-PEPDITWF--KDGEAIHIENIADIIPN---GELNGNQLKITRIKEGDAGKYTCEADNSAGSVEQDVNV-NVITIPKIEKDGIPSDYESQQNERVVISCPVYARPPAKITW--LKAGKPLQSDKFVKTSANGQKLYLFKLRETDSSKYTCIATNEAGTDKRDFKVSMLVAPSFDEPNIVRRITVNSGNPSTLHCPAKGSPSPT-ITWLKDGNAIEPNDRYVFFDAGRQLQISKTEGSDQGRYTCIATN----SVGSDDLENTLEVII--------PPVIDGERREAVAVIEGFSSELFCDSNSTG--------VDVEWQKDGLTINQDTLRGDSFIQIPSSGKKMSFLSARKSDSGRYTCIVRNPAGE--ARKLFDFAVNDPPSISDELSSANIQTIVPY----YPVEINCVVSGSPHPKVYWLFDDKPLEPDSAAYELTNNGETLKIVRSQV---------------------EHAGTYTCEAQNNVGKARKDFLVRVTAPPHFE---KEREEVVARVGDTMLLTCNAESSVPLSSVYWHAHDESVQNGVITSKYAANE-------------------KTLNVTNIQLDDEGFYYCTAVNEAGITKKFFKLIVIETP 2854 HSP 2 Score: 94.3597 bits (233), Expect = 4.775e-19 Identity = 148/706 (20.96%), Postives = 273/706 (38.67%), Query Frame = 3 Query: 306 KPCVVPDSESQITISHESRLTIHNISSDNSGYYVCRVTLLTTSEHIISLAVVTVKTPPKSISFHFNKSINVFQEQEFIAIQCSVSGGIPPPKISMYIVKDNAIKRLKIISSNFPNSTIAEVSAISLW-RPHYLENRGFVMCTAINDAGVLTKNTSLLNIKYKPKIKPFVPNTVNAMINQTIDLSCEV-YANPAATIQWV-----IMQGLQI-IDSSKFIAKIR---PDMDGPLICEAKNYLGSTKETVQLNVLRDP-----------------------LIHIDSNYRVPKNSNYSINCRVTSNPPPEFIKWYKLSN--MTDSSAVLISDDAKLNFILIDRSSTGMYACVTQNIQISTTGKRKPANSEKTMFLTVTYKPKEPQILGNKIISIMKGEKFIIKCSTDRKSPGEPFPTLKWIDVE---TKDIVSDMETFQVINSESRHNGKYKCLAENEIGKSFSRETALVTVNEAPSIITQHKNRKVFLSYSDLPQSISFTCEFRGQPLYEARWRYGNEKIPPSSQDFKIEDHRNISNERISQIFTKLTIDLYSRTFSQQTSLRSSPNGRYNCEADNRHGIASLDYFLXXXXXXXXXXNIRHRKIAASLNQNVVMIRCQAESISTMHIKWYKTNEHIVLPFQSKKYSIFEAEVTKYEPERDLFTPGLKVNELTIKDLENDDFSNYSCVASNDQGIKKVNFEVVFKSQP 2306 K + PD +I +E +L I +++G Y C + + + +A ++V P I +N+ ++ + +QC ++ GIPPP+I ++ ++ + N +++ +L +E++G C A N G +++T+L+ + VP + Q + LSC V P +I W+ + +G I I+ + ++R P +G C A + G++ + + +++ P + ++S + V ++I C V+ PPP I WY +S ++ D L D+S +G+Y C N + G N +KT + P G +++ + F I C G+P P + W+ + T+ +V++ + + N H G + C A+N G T +TV+ P+I +++ K+ L D I C + P W Y EKI D ++ H TI Q L ++ G + C+ N G SL Y L + P I + + + + I C+A + + W K I L KK+S+ + L I + + +D NY+CV +N+ G ++ V + P Sbjct: 741 KDLIKPDDYIKI---NEGQLHIMGAKDEDAGAYSCVGENMAGKD--VQVANLSVGRVPTIIESPHTVRVNIERQ---VTLQC-LAVGIPPPEIEW--------QKGNVLLATLNNPRYTQLADGNLLITDAQIEDQGQFTCIARNTYGQQSQSTTLMVTGLVSPVLGHVPPEEQLIEGQDLTLSCVVVLGTPKPSIVWIKDDKPVEEGPTIKIEGGGSLLRLRGGNPKDEGKYTCIAVSPAGNSTLHINVQLIKKPEFVYKPEGGIVFKPTISGMDEKHVAVVNSTHDVLDGEGFAIPCVVSGTPPP-IITWYLDGRPITPNSRDFTVTADNTLIVRKADKSYSGVYTCQATN----SAGD----NEQKTTIRIMNTPMISP---GQSSFNMVVDDLFTIPCDVY----GDPKPVITWLLDDKPFTEGVVNEDGSLTIPNVNEAHRGTFTCHAQNAAGND--TRTVTLTVHTTPTINAENQ-EKIALQNDD----IVLECPAKALPPPVRLWTYEGEKI-----DSQLIPH---------------TIREDGALVLQNVKLENT--GVFVCQVSNLAGEDSLSYTLTVHEKPKIISEVP--GVVDVVKGFTIEIPCRATGVPEVIRTWNKNG--IDLKMDEKKFSVD------------------NLGTLRIYEADKNDIGNYNCVVTNEAGTSQMTTHVDVQEPP 1362 HSP 3 Score: 85.8853 bits (211), Expect = 2.296e-16 Identity = 152/735 (20.68%), Postives = 273/735 (37.14%), Query Frame = 3 Query: 165 NATVNSKENLTLECVVDQQNIVYSWEYKPFHIKSNIMSKVLGFCYFEKPCVVPDSESQITISHESRLTIHNISSDNSGYYVC-RVTLLTTSEHIISLAVVTVKTPPKSISFHFNKSINVFQEQEFIAIQCSVSGGIPPPKISMYIVKDNAIKRLKIISSNFPNSTIAEVSAISLWRPHYLENR-GFVMCTAINDAGVLTKNTSLLNIKYKPKIKPFVPNTVNAMINQTIDLSCEVYANPAATIQWVIMQGLQIIDSSKFIAKI-----RPDM---DGPLICEAKNYLGSTKETVQLNVLRDPLIHIDSNYRVPKNSN-YSINCRVTSNPPPEFIKWYKLSNMTDSSAVLISDDAKLNFILIDRSST----GMYACVTQNIQISTTGKRKPANSEKTMFLTVTYKPKEPQILGNKIISIMKGEKFIIKCSTDRKSPGEPFPTLKWI------DVETKDIVSDMETFQVINSESRHNGKYKCLAENEIGKS--------FSRETALVTVNEAPSIITQHKNRKVFLSYSDLPQSISFTCEFRGQPLYEARWRYGNEKIPPSSQDFKIEDHRNISNERISQIFTKLTIDLYSRTFSQQTSLRSSPNGRYNCEADNRHGIASLDYFLXXXXXXXXXXNIRHRKIAASLNQNVVMIRCQAESISTMHIKWYKTNEHIVLPFQSKKYSIFEAEVTKYEPERDLFTPGLKVNELTIKDLENDDFSNYSCVASNDQGIKKVNF 2282 N V + + LTLEC ++ + V+ + F + D +Q + S +S+L I + +++ Y C V +E + VTV TPPK F S + I C G IPPP+IS ++ ++ P T + +SL + N+ G C A N AG ++T + I P++ + + + + CEV+ NP + W+ D +F K+ R G C A N G ++ T + VL P I + K N Y ++C+VT P P ++ W + + + N +L R++T G Y+C+ N + A+ +F T++ E +I++GE I+C D G P PT+ W+ +++ + +T ++ ++ G Y C+A N G S +++ T+++ P + + I C G P W+ G++ +P S+ H ++N DL + S+ + G+Y+C A N G + Y + P + + + + + + C S I W++ ++ + L +YSI P+ + +TI + D Y C ASN+ G ++ Sbjct: 2951 NVEVQAGDPLTLECPIEDTSGVHITWSRQFGKDGQL-----------------DMRAQSS-SDKSKLYIMQATPEDADSYSCIAVNDAGGAEAVFQ---VTVNTPPKIFGDSF--STTEIVADTTLEIPCRTEG-IPPPEISWFLDGKPILE--------MPGVTYKQ-GDLSLRIDNIKPNQEGRYTCVAENKAGRAEQDT-YVEISEPPRVV-MASEVMRVVEGRQTTIRCEVFGNPEPVVNWLKDGEPYTSDLLQFSTKLSYLHLRETTLADGGTYTCIATNKAGESQTTTDVEVLVPPRIEDEERVLQGKEGNTYMVHCQVTGRPVP-YVTWKRNGKEIE----------QFNPVLHIRNATRADEGKYSCIASNEAGTAV-----ADFLIDVFTKPTFETHE------TTFNIVEGESAKIECKID----GHPKPTISWLKGGRPFNMDNIILSPRGDTLMILKAQRFDGGLYTCVATNSYGDSEQDFKVNVYTKPYIDETIDQTPKAVAGGE--------------IILKCPVLGNPTPTVTWKRGDDAVPNDSR------HTIVNN-----------YDL------KINSVTTEDAGQYSCIAVNEAGNLTTHYAAEVIGKPTFVR--KGGNLYEVIENDTITMDCGVTSRPLPSISWFRGDKPVYL---YDRYSI--------SPDG---------SHITINKAKLSDGGKYICRASNEAGTSDIDL 3565 HSP 4 Score: 84.7297 bits (208), Expect = 4.354e-16 Identity = 159/677 (23.49%), Postives = 256/677 (37.81%), Query Frame = 3 Query: 363 LTIHNISSDNSGYYVCRVTLLTTSEHIISLA--VVTVKTPPKSISFHFNKSINVFQEQEFIAIQCSVSGGIPPPKISMYIVKDNAIKRLKIISSNFPNSTIAEVSAISLWRPHYLENRGFVMCTAINDAGVLTKNTSLLNIKYKPKIKPFVPNTVNAMINQTIDLSCEVYANPAATIQWVIMQGLQIIDSSKFIA--------KIRPDMDGPLICEAKNYLGSTKETVQLNVLRDP-LIHIDSN-YRVPKNSNYSINCRVTSNPPPEFIKWY----------KLSNMTDSSAVLISDDAKLNFILIDRSSTGMYACVTQNIQISTTGKRKPANSEKTMFLTVTYKPK--EPQILGNKIISIMKGEKFIIKCSTDRKSPGEPFPTLKW----IDVETKD----IVSDMETFQVINSESRHNGKYKCLAENEIGKSFSRETALVTVNEAPSIITQHKNRKVFLSYSDLPQSISFTCEFR-----GQPLYEARWRYGNEKIPPSSQDFKIEDHRNISNERISQIFTKLTIDLYSRTFSQQTSLRSSPNGRYNCEADNRHGIASLDYFLXXXXXXXXXXNIRHRKIAASLNQNVVMIRCQAESISTMHIKWYKTNEHIVLPFQSKKYSIFEAEVTKYEPERDLFTPGLKVNELTIKDLENDDFSNYSCVASNDQGIKKVNF 2282 L I N + + G Y C + ++E ++A ++ V T P +F +++ E E I+C + G P P IS ++ II S ++ + + + + G C A N G ++ + N+ KP I + T A+ I L C V NP T+ W DS I + + G C A N G+ V+ P + N Y V +N +++C VTS P P I W+ + S D S + I + AKL S G Y C N + S+ + L + PK + I+GN + + + ++C G P P + W +D+ D + + ETF + N + G+Y C A N GK+ S + +L + +P H + D +I+ TC + + + W ++D + D N IS KLTI Q SL ++ G Y C A NR G ASL++ + I PP+I + + ++NQ +M RC IKW K + + + I E + L I ++D +SCVA ND G+K++ Sbjct: 3264 LHIRNATRADEGKYSC----IASNEAGTAVADFLIDVFTKP---TFETHETTFNIVEGESAKIECKIDGH-PKPTIS-WLKGGRPFNMDNIILSPRGDT-------LMILKAQRFDG-GLYTCVATNSYGDSEQDFKV-NVYTKPYIDETIDQTPKAVAGGEIILKCPVLGNPTPTVTWKRGDDAVPNDSRHTIVNNYDLKINSVTTEDAGQYSCIAVNEAGNLTTHYAAEVIGKPTFVRKGGNLYEVIENDTITMDCGVTSRPLPS-ISWFRGDKPVYLYDRYSISPDGSHITI-NKAKL-------SDGGKYICRASN---------EAGTSDIDLILKILVPPKIDKSNIIGNPLAIVAR--TIYLECPIS----GIPQPDVIWTKNGMDINMTDSRVILAQNNETFGIENVQVTDQGRYTCTATNRGGKA-SHDFSLDVL--SPPEFDIHGTQPTIKREGD---TITLTCPIKLAEDIADQVMDVSW----------TKDSRALDGDLTDNVDISDDGRKLTI--------SQASLENA--GLYTCIALNRAGEASLEFKVEILSPPVIDISRNDVQPQVAVNQPTIM-RCAVTGHPFPSIKWLKNGKEVT---DDENIRIVE-----------------QGQVLQILRTDSDHAGKWSCVAENDAGVKELEM 3851 HSP 5 Score: 83.9593 bits (206), Expect = 7.278e-16 Identity = 145/704 (20.60%), Postives = 267/704 (37.93%), Query Frame = 3 Query: 291 FCYFEKPCVVPDSESQITISHESRLTIHNISSDNSGYYVCRVTLLTTSEHIISLA----VVTVKTPPKSISFHFNKSIN--VFQEQEFIAIQCSVSGGIPPPKISMYIVKDNAIKRLKIISSNFPNSTIAEVSAISLWRPHYLENRGFVMCTAINDAGVLTKNTSLLNIKY-----KPKIKPFVPNTVNAMINQTIDLSCEVYANPAATIQWVI-------MQGLQIIDSSKFIAKIRPDMDGPLICEAKNYLGSTKETVQLNVLRDPLIHID-SNYRVPKNSNYSINCRV--TSNPPPEFIKWYKLSNMTDSSAVLISDDAKLNFILIDRSSTGMYACVTQNIQISTTGKRKPANSEKTMFLTVTYKPKEPQILGNKI--ISIMKGEKFIIKCSTDRKSPGEPFPTLKWIDVETKDIV---------SDMETFQVINSESRHNGKYKCLAENEIGKSFSRETALVTVNEAPSIITQHKNRKVFLSYSDLPQSISFTCEFRGQPLYEARWRYGNEKIPPSSQDFKIEDHRNISNERISQIFTKLTIDLYSRTFSQQTSLRSSPNGRYNCEADNRHGIASLDYFLXXXXXXXXXXNIRHRKIAASLNQNVVMIRCQAESISTMHIKWYKTNEHIVLPFQSKKYSIFEAEVTKYEPERDLFTPGLKVNELTIKDLENDDFSNYSCVASNDQGIKKVNFEVVFKSQP 2306 + F+ + PDS + ++ L I +++G Y C +++ + A +V V PP HF K V + + + + C+ +P + + D +++ I S N V+ I L ++ GF CTA+N+AG+ K L+ I+ + K+ P + + + + L C P TI ++ + II S+ I + +++G C A+N G +++ + + VL P + + N V ++ C + TS + + + D A SD +KL + Y+C+ N A + +F P P+I G+ I+ I C T+ G P P + W ++ K I+ D+ + ++ N + G+Y C+AEN+ G++ + V ++E P ++ + +V + + CE G P W E P + D + Q TKL+ L+ R +T+L + G Y C A N+ G + + + PP I+ ++ N M+ CQ ++ W + + I + F P L I++ D YSC+ASN+ G +F + ++P Sbjct: 2701 YWLFDDKPLEPDSAAYELTNNGETLKIVRSQVEHAGTYTCE------AQNNVGKARKDFLVRVTAPP-----HFEKEREEVVARVGDTMLLTCNAESSVPLSSVYWH-AHDESVQNGVITSKYAANEKTLNVTNIQL------DDEGFYYCTAVNEAGITKKFFKLIVIETPYFLDQQKLYPII-------LGKRLTLDCSATGTPPPTILFMKDGKRLNESDEVDIIGSTLVIDNPQKEVEGRYTCIAENKAGRSEKDMMVEVLLPPKLSKEWINVEVQAGDPLTLECPIEDTSGVHITWSRQFGKDGQLDMRAQSSSDKSKLYIMQATPEDADSYSCIAVN----------DAGGAEAVFQVTVNTP--PKIFGDSFSTTEIVADTTLEIPCRTE----GIPPPEISWF-LDGKPILEMPGVTYKQGDL-SLRIDNIKPNQEGRYTCVAENKAGRA--EQDTYVEISEPPRVVMASEVMRVVEG-----RQTTIRCEVFGNPEPVVNWLKDGE---PYTSD-------------LLQFSTKLSY-LHLR----ETTL--ADGGTYTCIATNKAGESQTTTDVEVLVPPRIED---EERVLQGKEGNTYMVHCQVTGRPVPYVTWKRNGKEI-----------------------EQFNPVLH-----IRNATRADEGKYSCIASNEAGTAVADFLIDVFTKP 3300 HSP 6 Score: 80.1073 bits (196), Expect = 1.096e-14 Identity = 122/562 (21.71%), Postives = 225/562 (40.04%), Query Frame = 3 Query: 342 TISHESRLTIHNISSDNSGYYVCRVTLLTTSEHIISLAVVTVKTPPKSISFHFNKSINVFQEQEFIAIQCSVSGGIPPPKISMYIVKDNAIKRLKIISSNFPNSTIAEVSAISLWRPHYLENRGFVMCTAINDAGVLTKNTSLLNIKYKPKIKPFVPNTVNAMINQTIDLSCEVYANPAATIQWVIMQGLQI-IDSSKFIAKIRPDMDGPLI-------------CEAKNYLGSTKETVQLNVLRDPLIH---IDSNYRVPKNSNYSINCRVTSNPPPEFIKWYKLSN--MTDSSAVLISDDA-KLNFILIDRSSTGMYACVTQNIQISTTGKRKPANSEKTMFLTVTYKPKEPQILGNKIISIMKGEKFIIKCSTDRKSPGEPFPTLKWI----------DVETKDIVSDMETFQVINSESRHNGKYKCLAENEIGKSFSRETALVTVNEAPSIITQHKNRKVFLSYSDLPQSISFTCEFRGQPLYEARWRY---GNEKIPPSSQDFKIEDHRNISNERISQIFTKLTIDLYSRTFSQQTSLRSSPNGRYNCEADNRHGIA 1928 TI + L + N+ +N+G +VC+V+ L + + +TV PK IS ++V + I I C +G P I + N I LK+ F ++ + + ++ + G C N+AG ++ T+ ++++ P I P A++ ++L C V A+P A++ W +G+ I D+ ++ + DG L+ C+A N G + +Q+ V+ P I + + + ++ +S+ C V SNP P+ I WY + D ++ SDD KL+ + +G+Y CV +N K+ + V + K + +GE+ + C G P P + W+ + + +D T + + G Y C+A+++ G + L + A I+ + N +VFL + IS +C+ + + + + + G+E P + + HR LY T + NG+Y C N G A Sbjct: 1227 TIREDGALVLQNVKLENTGVFVCQVSNLAGEDSL--SYTLTVHEKPKIIS-EVPGVVDVVKGFT-IEIPCRATG--VPEVIRTW--NKNGID-LKMDEKKF---SVDNLGTLRIYEADK-NDIGNYNCVVTNEAGT-SQMTTHVDVQEPPIILPSTQTNNTAVVGDRVELKCYVEASPPASVTW-FRRGIAIGTDTKGYVV----ESDGTLVIQSASVEDATIYTCKASNPAGKAEANLQVTVIASPDIKDPDVVTQESIKESHPFSLYCPVFSNPLPQ-ISWYLNDKPLIDDKTSWKTSDDKRKLHVFKAKITDSGVYKCVARNAA---------GEGSKSFQVEVIVPLNLDESKYKKKVFAKEGEEVTLGCPVS----GFPVPQINWVVDGTVVEPGKKYKGATLSNDGLTLHFDSVSVKQEGNYHCVAQSK-GNILDIDVELSVL--AVPIVGEDDNLEVFLG-----KDISLSCDLQTESDDKTTFVWSINGSESDRPDNVQIPSDGHR-----------------LYI------TDAKPENNGKYMCRVTNSAGKA 1724 HSP 7 Score: 78.9518 bits (193), Expect = 2.814e-14 Identity = 130/565 (23.01%), Postives = 214/565 (37.88%), Query Frame = 3 Query: 330 ESQITISHESRLTIHNISSDNSGYYVCRVTLLTTSEHIISLAVVTVKTPPKSISFHFNKSINVFQ--EQEFIAIQCSVSGGIPPPKISMYIVKDNAIKRLKIISSNFPNSTIAEVSAISLWRPHYLENRGFVMCTAINDAGVLTKNTSL-LNIKYKPKI-KPFVPNTVNAMINQTIDLSCEVYANPAATIQWVIMQGLQI--IDSSKFIAK---------IRPDMDGPLICEAKNYLGSTKETVQLNVLRDPLIHIDSNYRVPKNSNYSINCRVTSNPPPEF------IKWYKLSNMTDSSA---VLISDDA-KLNFILIDRSSTGMYACVTQNIQISTTGKRKPANSEKTMFLTVTYKPKEPQILGNKIISIMKGEKFIIKCSTDRKSPGEPFPTLKWI-------DVETKDIVSDMETFQVINSESRHNGKYKCLAENEIGKSFSRETALVTVNEAPSIITQHKNRKVFLSYSDLPQSISFTCEFRGQPLYEARWRYGNEKIPPSSQDFKIEDHRNISNERISQIFTKLTIDLYSRTFSQQTSLRSSPNGRYNCEADNRHGIA 1928 +S+ TI + L I++++++++G Y C + + A + P K N+++ E + I + C V+ P P IS + D + S + S I A L + G +C A N+AG T + L L I PKI K + A++ +TI L C + P + W G+ I DS +A+ ++ G C A N G L+VL P I K +I + + W K S D V ISDD KL + G+Y C+ N + + K + ++ +PQ+ N + I++C+ G PFP++KW+ D E IV + Q++ ++S H GK+ C+AEN+ G +E +V P +++ + + L ++I+ C G P + +W G I F D RIS +L I L+ + G Y C+A N G + Sbjct: 3434 DSRHTIVNNYDLKINSVTTEDAGQYSC-IAVNEAGNLTTHYAAEVIGKP-----TFVRKGGNLYEVIENDTITMDCGVTSR-PLPSIS-WFRGDKPVYLYDRYSISPDGSHITINKA-------KLSDGGKYICRASNEAG--TSDIDLILKILVPPKIDKSNIIGNPLAIVARTIYLECPISGIPQPDVIWT-KNGMDINMTDSRVILAQNNETFGIENVQVTDQGRYTCTATNRGGKASHDFSLDVLSPPEFDIHGTQPTIKREGDTITLTCPIKLAEDIADQVMDVSWTKDSRALDGDLTDNVDISDDGRKLTISQASLENAGLYTCIALNRAGEASLEFK-VEILSPPVIDISRNDVQPQVAVN--------QPTIMRCAVT----GHPFPSIKWLKNGKEVTDDENIRIVEQGQVLQILRTDSDHAGKWSCVAENDAG---VKELEMVLDVFTPPVVSVKSDNPI----KALGETITLFCNASGNPYPQLKWAKGGSLI------FDSPD-----GARISLKGARLDI----------PHLKKTDVGDYTCQALNAAGTS 3939 HSP 8 Score: 77.0258 bits (188), Expect = 9.867e-14 Identity = 148/650 (22.77%), Postives = 248/650 (38.15%), Query Frame = 3 Query: 516 VFQEQEFIAIQCSVSGG---IPPPKISMYIVKDNAI-----KRLKIISSNFPNSTIAEVSAISLWRPHYLENRGFVMCTAINDAGVLTKNTSLLNIKYKPKIKPFVPNTVNAMINQT--IDLSCEVYANPAATIQWVIMQGLQIIDSSKFIAKIRPDMD--------GPLICEAKNYLGSTKETVQLNVLRDPLIH---IDSNYRVPKNSNYSINCRVTSNPPPEFIKWYKLSNMTDSSAVLISDDAKLNFILIDRSST---GMYACVTQNIQISTTGKRKPANSEKTMFLTVTYKPKEPQILGNKIISIMKGEKFIIKCSTDRKSPGEPFPTLKWI-------DVETKDIVSDMETFQVINSESRHNGKYKCLAENEIGKS-FSRETALVTVNEAPSIITQHKNRKVFLSYSDLPQSISFTC------EFRGQPLYEARWRYGNEKIPPSSQDFKIEDHR--NISNERISQIFTKLTIDLYSRTFSQQTSLRSSPNGRYNCEADNRHGIASLDYFLXXXXXXXXXXNIRHRKIAASLNQNVVMIRCQAESISTMHIKWYKTNEHIVLPFQSKKYSIFEAEVTKYEPERDLFTPG-LKVNELTIKDLENDDFSNYSCVASNDQGIKKVNFEVVFKSQPDPPYDLRVTDFE 2342 +F+E E I + C VS G I K + + +++AI RL I+++N R H C A N AG ++K+ ++ ++ PKIK V V IN+ I L+C+ NP T +W QG + + F+ + G C A N +G +T+ ++V P +S V + ++ C V + I W + + A F+ I + T G YAC N + + KT L V P G ++++ ++ C G+P P + W D+++ ++S+ + F+++++E H G Y C+A+N++G + S + ++T P I KN + LP F C F+GQ + W + I D + ED R +SN+R +LTI ++ + G+Y+C N G S D F P + K ++ + V + C A I W+K E I + E D+ G L N+L I ++ D Y+C A N G + + V + P D +D+E Sbjct: 1837 IFRESETITLDCPVSLGDFQITWMKQGLPLTENDAIFTLDNTRLTILNAN---------------RDH----EDIYTCVANNTAGQVSKDFDVV-VQVLPKIKNAV---VTLEINEGEEIILTCDAEGNPTPTAKWDFNQG-DLPKEAVFVNNNHTVVVNNVTKYHTGVYKCYATNKVGQAVKTINVHVRTKPRFESGLTESELTVNLTRSITLECDV-DDAIGVGISWTVNGKPFLAETDGVQTLAGGRFLHIVSAKTDDHGSYACTVTN---------EAGVATKTFNLFVQVPPTIVNEGGE--YTVIENNSLVLPCEVT----GKPNPVVTWTKDGRPVGDLKSVQVLSEGQQFKIVHAEIAHKGSYICMAKNDVGTAEISFDVDIIT---RPMIQKGIKNIVTAIKGGALP----FKCPIDDDKNFKGQII----WLRNYQPI-----DLEAEDARITRLSNDR------RLTI----------LNVTENDEGQYSCRVKNDAGENSFD-FKATVLVPPTIIMLDKDKNKTAVEHSTVTLSCPATGKPEPDITWFKDGEAIHI-----------------ENIADIIPNGELNGNQLKITRIKEGDAGKYTCEADNSAGSVEQDVNVNVITIPKIEKDGIPSDYE 2396 HSP 9 Score: 72.0182 bits (175), Expect = 3.503e-12 Identity = 137/614 (22.31%), Postives = 240/614 (39.09%), Query Frame = 3 Query: 318 VPDSESQITISHESRLTIHNISSDNSGYYVCRVTLLTTSEHIISLAVVTVKTPPKSISFHFNKSINVFQEQEFIAIQCSVSGGIPPPKISMYIVKDNAIKRLKIISSNFPNSTIAEVSAISLWRPHYLE-NRGFVMCTAINDAGVLTKNTSLLNIKYKPKI-KPFVPNTVNAMINQTIDLSCEVYANPAATIQWVI--------MQGLQIIDSSKFIA--KIRPDMDGPLICEAKNYLGSTKETVQLNVLRDPLIHIDSNYRVPKNSNYSINCRVTSNPPPEFIKWYKLSNMTDSS--AVLISDDAKLNFILIDRS-STGMYACVTQNIQISTTGKRKPANSEKTMFLTVTYKPKEPQILGN--KIISIMKGEKFIIKCSTDRKSPGEPFPTLKWI-------DVETKDIVSDMETFQVINSESRHNGKYKCLAENEIGKSFSRETALVTVNEAPSIITQHKNRKVFLSYSDLPQSISFTCEFRGQPLYEARWRYGNEKIPPSSQDFKIEDHRNISNERISQIFTKLTIDLYSRTFSQQTSLRSSPNGRYNCEADNRHGIASLDYFLXXXXXXXXXXNIRHRKIAASLNQNVVMIRCQAESISTMHIKWYKTNE 2087 V D E+ + L I SD++G + C + + L +V P +S + I E I + C+ SG P P++ K ++ I S P+ + L PH + + G C A+N AG + S+ ++ P+I + + + Q++ L C P ++W + G+ + S FI + G C A+N GS ++V++ P+I +V + I C V P P+ + W + N ++ V D ++ I+ RS +G+Y C S T + A T+ + V+ P+I+ + +++ G KF + C+ G P P + W D E + T + +E RH Y+C A+N+ G + E + T+ AP I T NR +++ S+ +++ CE + + + G +P ++ F ED++ I + S R S G Y+C A N+ G A+ L + P I R + + + V + C+A + I WYK NE Sbjct: 3808 VTDDENIRIVEQGQVLQILRTDSDHAGKWSC---VAENDAGVKELEMVLDVFTPPVVSVKSDNPIKALGET--ITLFCNASGN-PYPQLKW--AKGGSL----IFDS--PDGARISLKGARLDIPHLKKTDVGDYTCQALNAAGTSEASVSV-DVLVPPEINRDGIDMSPRLPAQQSLTLQCLAQGKPVPQMRWTLNGTALTHSTPGITVASDSTFIQINNVSLSDKGVYTCYAENVAGSDNLMYNVDVVQAPVISNGGTKQVIEGELAVIECLVEGYPAPQ-VSWLRNGNRVETGVQGVRYVTDGRMLTIIEARSLDSGIYLC-------SATNEAGSAQQAYTLEVLVS-----PKIITSTPGVLTPSSGSKFSLPCAVR----GYPDPIISWTLNGNDIKDGENGHTIGADGTLHIEKAEERHL-IYECTAKNDAGAD-TLEFPVQTI-VAPKISTS-GNR--YINGSEGTETV-IKCEIESESSEFSWSKNGVPLLPSNNLIFS-EDYKLI----------------------KILSTRLSDQGEYSCTAANKAGNATQKTNLNVGVAPKIMERPRTQVVHKG---DQVTLWCEASGVPQPAITWYKDNE 4356 HSP 10 Score: 70.4774 bits (171), Expect = 1.012e-11 Identity = 144/689 (20.90%), Postives = 249/689 (36.14%), Query Frame = 3 Query: 330 ESQITISHESRLTIHNISSDNSGYYVCRVTLLTTSEHIISLAVVTVKTPPKSISFHFNKSINVFQEQEFIAIQCSVSGGIPPPKISMYIVKDNAIKRLKIISSNFPNSTIAEVSAISLWRPHYLENRGFVMCTAINDAGVLTKNTSLLNIKYKPKIK-PFVPNTVNAMINQTIDLSCEVYANPAATIQWVIMQGLQIIDSSKF----------IAKIRPDMDGPLICEAKNYLGSTKETVQLNVLRDPLIHIDSNYR----VPKNSNYSINCRVTSNPPPEFIKWYKLSNMTD-----SSAVLISDDAKLNFILIDRSSTGMYACVTQNIQISTTGKRKPANSEKTMFLTVTYKPKEPQILGNKIISIMKGEKFIIKCSTDRKSPGEPFPTLKW-IDVETKD------IVSDMETFQVINSESRHNGKYKCLAENEIGKSFSRETALVTVNEAPSIITQ--HKNRKVFLSYSDLPQSISFTCEFRGQPLYEARWRYGNEKIPPSSQDFKIEDHRNISNERISQI-FTKLTIDLYSRTFSQQTSLRSSPNGRYNCEADNRHGIASLDYFLXXXXXXXXXXNIRHRKIAASLNQNVVMIRCQAESISTMHIKWYKTNEHIVLPFQSKKYSIFEAEVTKYEPERDLFTPGLKVNELTIKDLENDDFSNYSCVASNDQGIKKVNFEVVFKSQP 2306 E + ++ + L I+ ++ G Y C VT + + + V V+ PP I ++ N + + ++C V PP ++ + R I + E + + +E+ C A N AG N + I P IK P V + + L C V++NP I W + I D + + + K + G C A+N G ++ Q+ V+ PL +S Y+ + ++ C V+ P P+ I W + + A L +D L+F + G Y CV Q + G + E ++ P + + + + G+ + C D ++ + T W I+ D I SD + +++ +NGKY C N GK+ T + V E P + N+K+ + I C+ G P W+ + D + +E +S + KLT + + +C A+N+ G AS D+F+ P K I + + C S+ I W K LP ++ +IF + T+ LTI + D Y+CVA+N G +F+VV + P Sbjct: 1315 EKKFSVDNLGTLRIYEADKNDIGNYNCVVTNEAGTSQMTTH--VDVQEPP--IILPSTQTNNTAVVGDRVELKCYVEAS-PPASVTWF--------RRGIAIGTDTKGYVVESDGTLVIQSASVEDATIYTCKASNPAGKAEANLQVTVIA-SPDIKDPDVVTQESIKESHPFSLYCPVFSNPLPQISWYLNDKPLIDDKTSWKTSDDKRKLHVFKAKITDSGVYKCVARNAAGEGSKSFQVEVIV-PLNLDESKYKKKVFAKEGEEVTLGCPVSGFPVPQ-INWVVDGTVVEPGKKYKGATLSNDGLTLHFDSVSVKQEGNYHCVAQ-----SKGNILDIDVELSVLAV-------PIVGEDDNLEVFLGKDISLSC--DLQTESDDKTTFVWSINGSESDRPDNVQIPSDGHRLYITDAKPENNGKYMCRVTNSAGKA--ERTLTLDVLEPPVFVEPVFEANQKLIGN-----NPIILQCQVTGNPKPTVIWKIDGNDV----------DKSWLFDESLSLLRIEKLT----------------GKSAQISCTAENKAGTASRDFFIQNIAAPTFKNEGDQETIFRE--SETITLDCPV-SLGDFQITWMKQG----LPL-TENDAIFTLDNTR----------------LTILNANRDHEDIYTCVANNTAGQVSKDFDVVVQVLP 1916 HSP 11 Score: 67.781 bits (164), Expect = 6.611e-11 Identity = 115/559 (20.57%), Postives = 209/559 (37.39%), Query Frame = 3 Query: 702 ENRGFVMCTAINDAGVLTKNTSLLNIKYKPKIKPFVPNTVNAMINQTIDLSCEVYANPAATIQWVI----MQGLQIIDSSKFIAKIRP--DMDGPLICEAKNYLGSTKETVQLNVLRDPLIHIDSNYRV--PKNSNYSINCRVTSNPPPEF-IKWYKLS-NMTDSSAVLISDDAKLNFILIDRSSTGMYACVTQNIQISTTGKRKPANSEKTMFLTVTYKPKEPQILGNKIIS--IMKGEKFIIKCSTDRKSPGEPFPTLKWIDVETKDIVSDM------ETFQVINSESRHNGKYKCLAENEIGKSFSRETALVTVNEAPSIITQHKNRKVFLSYSDLPQSISFTCEFRGQPLYEARWRYGNEKIPPSSQDFKIEDHRNISNERISQIFTKLTIDLYSRTFSQQTSLRSSPNGRYNCEADNRHGIASLDYFLXXXXXXXXXXNIRHRKIAASLNQNVVMIRCQAESISTMHIKWYKTN------EHIVLPFQSKKYSIFEAEVTKYEPERDLFTPGLKVNELTIKDLENDDFSNYSCVASNDQGIKKVNFEVVFKSQP 2306 EN G MC N AG + +L ++ ++P + N I L C+V NP T+ W I + + D S + +I + C A+N G+ + + P + + ++ +++C V+ +F I W K +T++ A+ D+ +L + +R +Y CV N T G+ K + V PK + N +++ I +GE+ I+ C + G P PT KW D D+ + T V N H G YKC A N++G++ +T V V P + ++ + +L +SI+ C+ W + + F E T L F S ++ +G Y C N G+A+ + L ++ PP I + + N +++ C+ + W K + + + + +++ I AE+ +Y C+A ND G +++F+V ++P Sbjct: 1708 ENNGKYMCRVTNSAGKAERTLTLDVLEPPVFVEPVFEANQKLIGNNPIILQCQVTGNPKPTVIWKIDGNDVDKSWLFDESLSLLRIEKLTGKSAQISCTAENKAGTASRDFFIQNIAAPTFKNEGDQETIFRESETITLDCPVSLG---DFQITWMKQGLPLTENDAIFTLDNTRLTILNANRDHEDIYTCVANN----TAGQ-----VSKDFDVVVQVLPK----IKNAVVTLEINEGEEIILTCDAE----GNPTPTAKW-DFNQGDLPKEAVFVNNNHTVVVNNVTKYHTGVYKCYATNKVGQAV--KTINVHVRTKPRFESGLTESELTV---NLTRSITLECDVDDAIGVGISWTV-------NGKPFLAE--------------TDGVQTLAGGRFLHIVSAKTDDHGSYACTVTNEAGVATKTFNLFVQVPPTIVNEGGEYTV---IENNSLVLPCEVTGKPNPVVTWTKDGRPVGDLKSVQVLSEGQQFKIVHAEIAHK--------------------------GSYICMAKNDVGTAEISFDVDIITRP 2190 HSP 12 Score: 63.929 bits (154), Expect = 9.289e-10 Identity = 127/631 (20.13%), Postives = 239/631 (37.88%), Query Frame = 3 Query: 525 EQEFIAIQCSVSGGIPPPKISMYIVKDNAIKRLKIISSNFPNSTIAEVSAISLWRPHYLENRGFVMCTAINDAGVLTKNTSLLNIK-----YKPKIKPFVPNTVNAM-------INQTID--------LSCEVYANPAATIQWVIMQGLQII----------DSSKFIAKIRPDMDGPLICEAKNYLGSTKETVQLNVLRDPLIH-IDSNYRVPKNSNYSINCRVTSNPPPEFIKWYKLSNMTDSSAVLISDDAKLNFILIDRSSTGMYACVTQNIQISTTGKRKPANSEKTMFLTVTYKPKEPQILGNKIISIMKGEKFIIKCSTDRKSPGEPFPTLKWIDVETKDI---VSDMETFQVINSESRHNGKYKCLAENEIGKSFSRETALVTVNEAPSIITQHKNR-KVFLSYSDLPQSISFTCEFRGQPLYEARWRYGNEKIPPSSQDFKIEDHR-NISNERISQIFTKLTIDLYSRTFSQQTSLRSSPNGRYNCEADNRHGIASLDYFLXXXXXXXXXXNIRHRKIAASLNQNVVMIRCQAESISTMHIKWYKTNEHIVLPFQSKKYSIFEAEVTKYEPERDLFTPGLKVNELTIKDLENDDFSNYSCVASNDQGIKKVNFEVVFKSQPD 2309 E + + + C V G P P I ++I D ++ P I ++ R ++ G C A++ AG T + ++ IK YKP+ T++ M +N T D + C V P I W + G I D++ + K G C+A N G ++ + ++ P+I S++ + + ++I C V +P P I W L + + ++++D L ++ + G + C QN N +T+ LTV P KI ++ + +++C P T + ++++ I + + + N + + G + C N G+ T +TV+E P II++ V ++ I C G P W + D K+++ + ++ N +I+ D+ G YNC N G + + + ++ PPII + + A ++ V ++C E+ + W++ I + +K Y + E++ T L I+ +D + Y+C ASN G + N +V + PD Sbjct: 900 EGQDLTLSCVVVLGTPKPSI-VWIKDDKPVEE-------GPTIKIEGGGSLLRLRGGNPKDEGKYTCIAVSPAGNSTLHINVQLIKKPEFVYKPEGGIVFKPTISGMDEKHVAVVNSTHDVLDGEGFAIPCVVSGTPPPIITWY-LDGRPITPNSRDFTVTADNTLIVRKADKSYSGVYTCQATNSAGDNEQKTTIRIMNTPMISPGQSSFNMVVDDLFTIPCDVYGDPKP-VITW--LLDDKPFTEGVVNEDGSLTIPNVNEAHRGTFTCHAQNAA---------GNDTRTVTLTVHTTPTINAENQEKIA--LQNDDIVLECPAKALPPPVRLWTYEGEKIDSQLIPHTIREDGALVLQNVKLENTGVFVCQVSNLAGEDSLSYT--LTVHEKPKIISEVPGVVDVVKGFT-----IEIPCRATGVPEVIRTWNK-------NGIDLKMDEKKFSVDNLGTLRIYEADKNDI----------------GNYNCVVTNEAGTSQMTTHVDVQEPPIILPSTQTNNTAVVGDR--VELKCYVEASPPASVTWFRRG--IAIGTDTKGY-VVESDGT-----------------LVIQSASVEDATIYTCKASNPAGKAEANLQVTVIASPD 1455 HSP 13 Score: 61.6178 bits (148), Expect = 4.519e-9 Identity = 132/640 (20.62%), Postives = 233/640 (36.41%), Query Frame = 3 Query: 153 ITPNNATVNSKENLTLECVVDQQ-NIVYSWEY--KPFHIKSNIMSKVLGFCYFEKPCVVPDSESQITISHESRLTIHNISSDNSGYYVCRVTLLTTSEHIISLAV--VTVKTPPKSISFHFNKSINVFQEQEFIAIQCSVSGGIPPPKISMYIVKDNAIKRLKIISSNFPNSTIAEVSAISLWRPHYLENRGFVMCTAINDAGVLTKNTSL-LNIKYKPKIKPFVPNTVNAMINQTIDLSCEVYANPAATIQWVIMQGLQIIDSSKFIAKI--------------RPDMDGPLICEAKNYLGSTKETVQLNVLRDPLIHI---DSNYRVPKNSNYSINCRVTSNPPPEFIKWYKLSNMTDSSAVLISDDA-----------KLNFILIDRSSTGMYACVTQNIQISTTGKRKPANSEKTMFLTVTYKPKEPQILGNKIISIMKGEKFIIKCSTDRKSP--------GEPFPTLKWIDVETKDIVSDMETFQVINSESRHNGKYKCLAENEIGKSFSRETALVTVNEAPSIITQHKNRKVFLSYSDLPQSISFTCEFRGQPLYEARWRYGNEKIPPSSQDFKIEDHRNISNERISQIFTKLTIDLYSRTFSQQTSLRSSPNGRYNCEADNRHGIASLDYFL 1946 +T + TVN ++TLEC VD + SW KPF +++ + + G + L I + +D+ G Y C V T+E ++ + V+ PP ++ ++ E + + C V+G P + + + LK + ++E + + ++G +C A ND G T S ++I +P I+ + N V A+ + C + + Q + ++ Q ID A+I + +G C KN G + VL P I + D N ++S +++C T P P+ I W+K D A+ I + A +L I G Y C N + E+ + + V PK + + E+ +I C + P G+P + K+ V+T + F++ ++S KY C+A NE G + V++ APS + R++ ++ + P ++ C +G P W I P+ + + R + Q + S GRY C A N G L+ L Sbjct: 2011 LTESELTVNLTRSITLECDVDDAIGVGISWTVNGKPFLAETDGVQTLAGGRF---------------------LHIVSAKTDDHGSYACTV----TNEAGVATKTFNLFVQVPPTIVNEGGEYTV---IENNSLVLPCEVTG--KPNPVVTWTKDGRPVGDLKSV------QVLSEGQQFKIVHAE-IAHKGSYICMAKNDVG--TAEISFDVDIITRPMIQKGIKNIVTAIKGGALPFKCPIDDDKNFKGQIIWLRNYQPIDLEAEDARITRLSNDRRLTILNVTENDEGQYSCRVKNDAGENSFDFKATVLVPPTIIMLDKDKNKTAVEHSTVTLSCPATGKPEPD-ITWFK-----DGEAIHIENIADIIPNGELNGNQLKITRIKEGDAGKYTCEADN---------SAGSVEQDVNVNVITIPKIEKDGIPSDYESQQNERVVISCPVYARPPAKITWLKAGKPLQSDKF--VKTSANGQKLYLFKLRETDSS---KYTCIATNEAGT--DKRDFKVSMLVAPSFDEPNIVRRITVNSGN-PSTLH--CPAKGSPSPTITWLKDGNAIEPNDRYVFFDAGRQL----------------------QISKTEGSDQGRYTCIATNSVGSDDLENTL 2564 HSP 14 Score: 55.4546 bits (132), Expect = 3.501e-7 Identity = 65/315 (20.63%), Postives = 121/315 (38.41%), Query Frame = 3 Query: 357 SRLTIHNISSDNSGYYVCRVTLLTTSEHIISLAVVTVKTPPKSISFHFNKSINV-FQEQEFIAIQCSVSGGIPPPKISMYIVKDNAIKRLKIISSNFPNSTIAEVSAISLWRPHYL--ENRGFVMCTAINDAGVLTKNTSLLNIKYKPKIKPFVPNTVNAMINQTIDLSCEVYANPAATIQWVIMQ-------GLQIIDSSKF--IAKIRPDMDGPLICEAKNYLGSTKETVQLNVLRDPLIHIDSN-YRVPKNSNYSINCRVTSNPPPEFIKWYK-LSNMTDSSAVLISDDAKLNFILIDRSSTGMYACVTQNI 1259 S TI +S ++G Y CRV + + + V T ++PP+ ++++V E F+ +G + I+ + ++ F + H++ + G C A N G+ T+ L +I P +K P V + + ++LSCE +P + W Q+ SKF I +G C A + G ++T L + P + I N V + S C+ P I+W+K ++ + ++ +L+ + G Y+CV +N+ Sbjct: 482 SVWTIPELSLKDAGEYECRV-ISNNGNYSVKTRVETRESPPEIFGV---RNVSVPLGEAAFLHCSTRSAGEV-------------EIRWTRYGATVFNGPNTERNPTNGTLKIHHVTRADAGVYECMARNAGGMSTRKMRL-DIMEPPSVK-VTPQDVYFNMREGVNLSCEAMGDPKPEVHWYFKGRHLLNDYKYQVGQDSKFLYIRDATHHDEGTYECRAMSQAGQARDTTDLMLATPPKVEIIQNKMMVGRGDRVSFECKTIRGKPHPKIRWFKNGKDLIKPDDYIKINEGQLHIMGAKDEDAGAYSCVGENM 777 HSP 15 Score: 54.6842 bits (130), Expect = 5.999e-7 Identity = 96/423 (22.70%), Postives = 164/423 (38.77%), Query Frame = 3 Query: 516 VFQEQEFIAIQCSVSGGIPPPKISMYIVKDNAIKRLKIISSNFPNSTIAEVSAISLWRPHYLENRGFVMCTAINDAGVLTKNTSLLNIKYKPKIKPFVPNTVNAMIN--QTIDLSCEVYANPAATIQWVIMQGL--------QIIDSSKFIAKIRPDMDGPLICEAKNYLGSTKETVQLNV----LRDPLIHIDSNYRV-PKNSNYSINCRVTSNPPPEFIKWYKLSNMTDSSAVLISDDAKLNFILIDRSSTGMYACVTQNIQISTTGKRKPANSEKTMFLTVTYKPKEPQ-ILGNKIISIMKGEKFIIKCSTDRKSPGEPFPTLKWID----VETKDIVSDMETFQVINSESRHNGKYKCLAENEIGKSFSRETALVTVNE----APSIITQHKNRKVFLSYS-DLPQSISFTCEFRGQPL 1709 V + + + + C SG +P P I+ Y KDN +++++ + T ++ G C A N ++ L+ + P++ VP +N N QT+ LSC P I W+ + QI+ ++ I + PD DG C AK+ G T +L V R I ++ + + PK + Y I+ T + P+ + W + +D+ LN + Y C+ G R S +T+ L PQ I+ K + G ++CS + G P PT+ W +E +V + + +G+Y C+A+N +G S +A + V+ P + KN V Y + S T E+ G P+ Sbjct: 4328 VVHKGDQVTLWCEASG-VPQPAITWY--KDN-----ELLTNTGVDETATTKKKSVIFSSISPSQAGVYTCKAENWVASTEEDIDLI-VMIPPEV---VPERMNVSTNPRQTVFLSCNATGIPEPVISWMRDSNIAIQNNEKYQILGTTLAIRNVLPDDDGFYHCIAKSDAGQKIATRKLIVNKPSDRPAPIWVECDEKGKPKKTEYMIDRGDTPDDNPQLLPWKDV------------EDSSLNGSI-------AYRCM--------PGPR----SSRTVLLHAA-----PQFIVKPKNTTAAIGAIVELRCS----AAGPPHPTITWAKDGKLIEDSKFEIAYSHLKVTLNSTSDSGEYTCMAQNSVGSSTV--SAFINVDNNILPTPKPSSNQKNVAVITCYERNQAYSRGLTWEYNGVPM 4696
BLAST of hemicentin-1 isoform X2 vs. Ensembl Celegans
Match: him-4 (High Incidence of Males (Increased X chromosome loss) [Source:UniProtKB/TrEMBL;Acc:A4UVK0]) HSP 1 Score: 104.375 bits (259), Expect = 5.491e-22 Identity = 157/706 (22.24%), Postives = 278/706 (39.38%), Query Frame = 3 Query: 306 KPCVVPDSESQIT-ISHESRLTIHNISSDNSGYYVCRVTLLTTSEHIISLAVVTVKTPPKSISFHFNKSINVFQEQEFIAIQCSVSGGIPPPKISMYIVKDNAIKRLKIISSNFPNSTIAEVSAISLWRPHYLE-NRGFVMCTAINDAGVLTKNTSLLNIKYKPKI-KPFVPNTVNAMINQTIDLSCEVYANPAATIQWVIMQGLQIIDSSKFIA-----------KIRPDMDGPLICEAKNYLGSTKETVQLNVLRDPLI---HIDSNYRVPKNSNYSINCRVTSNPPPEFIKWYKLSNMTDSSAVLISDDA--KLNFILIDRSSTGMYACVTQNIQISTTGKRKPANSEKTMFLTVTYKPKEPQILGNKIISIMKGEKFIIKCSTDRKSPGEPFPTLKWIDVE-TKD----------------IVSDMETFQVINSESRHNGKYKCLAENEIGKSFSRETALVTVNEAPSIITQ--HKNRKVFLSYSDLPQSISFTCEFRGQPLYEARWRYGNEKIPPSSQDFKIEDHRNISNERISQIFTKLTIDLYSRTFSQQTSLRSSPNGRYNCEADNRHGIASLDYFLXXXXXXXXXXNIRHRKIAASLNQNVVMIRCQAE-SISTMHIKWYKTNEHIVLPFQSKKYSIFEAEVTKYEPERDLFTPGLKVNELTIKDLENDDFSNYSCVASNDQGIKKVNFEVVFKSQP 2306 +P + +++IT +S++ RLTI N++ ++ G Y CRV A V V PP I +K+ E + + C +G P P I+ + KD ++ I+ PN E++ L E + G C A N AG + ++ ++ N+ PKI K +P+ + N+ + +SC VYA P A I W ++ + + S KF+ K+R C A N G+ K ++++L P +I V + +++C +P P I W K N + + + DA +L + S G Y C+ N + G N+ + + P I G + ++ E F + D S G +DVE KD I S + +++ +G+Y C+ N G+ +R+ VN+ PSI + N + + Y + C G P + W + ++ + P S +++ ++ SQ+ G Y CEA N G A D+ + + PP + + R+ + + +++ C AE S+ + W+ +E + + KY+ E L + +++ DD Y C A N+ GI K F+++ P Sbjct: 2231 QPIDLEAEDARITRLSNDRRLTILNVTENDEGQYSCRVKNDAGENSFDFKATVLV--PPTIIMLDKDKNKTAV-EHSTVTLSCPATGK-PEPDITWF--KDGEAIHIENIADIIPN---GELNGNQLKITRIKEGDAGKYTCEADNSAGSVEQDVNV-NVITIPKIEKDGIPSDYESQQNERVVISCPVYARPPAKITW--LKAGKPLQSDKFVKTSANGQKLYLFKLRETDSSKYTCIATNEAGTDKRDFKVSMLVAPSFDEPNIVRRITVNSGNPSTLHCPAKGSPSPT-ITWLKDGNAIEPNDRYVFFDAGRQLQISKTEGSDQGRYTCIATN----SVGSDDLENTLEVII--------PPVIDGERREAVAVIEGFSSELFCDSNSTG--------VDVEWQKDGLTINQDTLRGDSFIQIPSSGKKMSFLSARKSDSGRYTCIVRNPAGE--ARKLFDFAVNDPPSISDELSSANIQTIVPY----YPVEINCVVSGSPHPKVYWLFDDKPLEPDSAAYELTNNGETLKIVRSQV---------------------EHAGTYTCEAQNNVGKARKDFLVRVTAPPHFE---KEREEVVARVGDTMLLTCNAESSVPLSSVYWHAHDESVQNGVITSKYAANE-------------------KTLNVTNIQLDDEGFYYCTAVNEAGITKKFFKLIVIETP 2854 HSP 2 Score: 94.3597 bits (233), Expect = 5.374e-19 Identity = 148/706 (20.96%), Postives = 273/706 (38.67%), Query Frame = 3 Query: 306 KPCVVPDSESQITISHESRLTIHNISSDNSGYYVCRVTLLTTSEHIISLAVVTVKTPPKSISFHFNKSINVFQEQEFIAIQCSVSGGIPPPKISMYIVKDNAIKRLKIISSNFPNSTIAEVSAISLW-RPHYLENRGFVMCTAINDAGVLTKNTSLLNIKYKPKIKPFVPNTVNAMINQTIDLSCEV-YANPAATIQWV-----IMQGLQI-IDSSKFIAKIR---PDMDGPLICEAKNYLGSTKETVQLNVLRDP-----------------------LIHIDSNYRVPKNSNYSINCRVTSNPPPEFIKWYKLSN--MTDSSAVLISDDAKLNFILIDRSSTGMYACVTQNIQISTTGKRKPANSEKTMFLTVTYKPKEPQILGNKIISIMKGEKFIIKCSTDRKSPGEPFPTLKWIDVE---TKDIVSDMETFQVINSESRHNGKYKCLAENEIGKSFSRETALVTVNEAPSIITQHKNRKVFLSYSDLPQSISFTCEFRGQPLYEARWRYGNEKIPPSSQDFKIEDHRNISNERISQIFTKLTIDLYSRTFSQQTSLRSSPNGRYNCEADNRHGIASLDYFLXXXXXXXXXXNIRHRKIAASLNQNVVMIRCQAESISTMHIKWYKTNEHIVLPFQSKKYSIFEAEVTKYEPERDLFTPGLKVNELTIKDLENDDFSNYSCVASNDQGIKKVNFEVVFKSQP 2306 K + PD +I +E +L I +++G Y C + + + +A ++V P I +N+ ++ + +QC ++ GIPPP+I ++ ++ + N +++ +L +E++G C A N G +++T+L+ + VP + Q + LSC V P +I W+ + +G I I+ + ++R P +G C A + G++ + + +++ P + ++S + V ++I C V+ PPP I WY +S ++ D L D+S +G+Y C N + G N +KT + P G +++ + F I C G+P P + W+ + T+ +V++ + + N H G + C A+N G T +TV+ P+I +++ K+ L D I C + P W Y EKI D ++ H TI Q L ++ G + C+ N G SL Y L + P I + + + + I C+A + + W K I L KK+S+ + L I + + +D NY+CV +N+ G ++ V + P Sbjct: 741 KDLIKPDDYIKI---NEGQLHIMGAKDEDAGAYSCVGENMAGKD--VQVANLSVGRVPTIIESPHTVRVNIERQ---VTLQC-LAVGIPPPEIEW--------QKGNVLLATLNNPRYTQLADGNLLITDAQIEDQGQFTCIARNTYGQQSQSTTLMVTGLVSPVLGHVPPEEQLIEGQDLTLSCVVVLGTPKPSIVWIKDDKPVEEGPTIKIEGGGSLLRLRGGNPKDEGKYTCIAVSPAGNSTLHINVQLIKKPEFVYKPEGGIVFKPTISGMDEKHVAVVNSTHDVLDGEGFAIPCVVSGTPPP-IITWYLDGRPITPNSRDFTVTADNTLIVRKADKSYSGVYTCQATN----SAGD----NEQKTTIRIMNTPMISP---GQSSFNMVVDDLFTIPCDVY----GDPKPVITWLLDDKPFTEGVVNEDGSLTIPNVNEAHRGTFTCHAQNAAGND--TRTVTLTVHTTPTINAENQ-EKIALQNDD----IVLECPAKALPPPVRLWTYEGEKI-----DSQLIPH---------------TIREDGALVLQNVKLENT--GVFVCQVSNLAGEDSLSYTLTVHEKPKIISEVP--GVVDVVKGFTIEIPCRATGVPEVIRTWNKNG--IDLKMDEKKFSVD------------------NLGTLRIYEADKNDIGNYNCVVTNEAGTSQMTTHVDVQEPP 1362 HSP 3 Score: 86.6557 bits (213), Expect = 1.221e-16 Identity = 133/549 (24.23%), Postives = 219/549 (39.89%), Query Frame = 3 Query: 249 PFHIKSNIMSKVLGFCYFEKP-CVVPDSESQITISHESR-LTIHNISSDNSGYYVC-------------RVTLLTTS-------EH---IISLAVVTVKTPPKSISFHFNK--------SINVFQEQEFI----AIQCSVSGGIPPPKISMYIVKDNAIKRLKIISSNFPNSTIAEVSAISLWRPHYLENRGFVMCTAINDAGVLTKNTSLLNIKYKPKIKPFVPNTVNAMINQTIDLSCEVYANPAATIQWVIMQGLQIIDSSKFIAKI-----RPDMD-------GPLICEAKNYLGSTKETVQLNVLRDPLIH---IDSNYRVPKNSNYSINCRVTSNPPPEFIKWYKLSNMTDSSAVLISDDAKLNFILIDR---SSTGMYACVTQNIQISTTGKRKPANSEKTMFLTVTYKPKEPQILGNKIISIMKGEKFIIKCSTDRKSPGEPFPTLKWI--------DVETKDIVSDMETFQVINSESRHNGKYKCLAENEIGKSFSRETALVTVNEAPSIITQHKNRKVFLSYSDLPQSISFTCEFRGQP 1706 P + +I +V+ + + + D + IS + R LTI S +N+G Y C +V +L TS EH I+ + V T P+ +S N S N Q Q + ++C+V+G P P I +K K ++ + + + + + R ++ G C A NDAGV + +L++ P + N + A+ +TI L C NP ++W +G +I S A+I R D+ G C+A N G+++ +V ++VL P I+ ID + R+P + ++ C P P+ ++W S I+ + FI I+ S G+Y C +N+ A S+ M+ + P I +++GE +I+C + G P P + W+ V+ V+D +I + S +G Y C A NE G + T V V +P IIT S S S C RG P Sbjct: 3690 PIKLAEDIADQVMDVSWTKDSRALDGDLTDNVDISDDGRKLTISQASLENAGLYTCIALNRAGEASLEFKVEILCTSLATVKCREHENNYIARHMPHVVTKPREMSQSANAYPPPVIDISRNDVQPQVAVNQPTIMRCAVTGH-PFPSIKW-------LKNGKEVTDDENIRIVEQGQVLQILRTDS-DHAGKWSCVAENDAGV-KELEMVLDVFTPPVVSVKSDNPIKAL-GETITLFCNASGNPYPQLKWA--KGGSLIFDSPDGARISLKGARLDIPHLKKTDVGDYTCQALNAAGTSEASVSVDVLVPPEINRDGIDMSPRLPAQQSLTLQCLAQGKPVPQ-MRWTLNGTALTHSTPGITVASDSTFIQINNVSLSDKGVYTCYAENV----------AGSDNLMYNVDVV--QAPVISNGGTKQVIEGELAVIECLVE----GYPAPQVSWLRNGNRVETGVQGVRYVTDGRMLTIIEARSLDSGIYLCSATNEAGSAQQAYTLEVLV--SPKIITSTPGVLTPSSGSKF----SLPCAVRGYP 4202 HSP 4 Score: 83.9593 bits (206), Expect = 8.330e-16 Identity = 145/704 (20.60%), Postives = 267/704 (37.93%), Query Frame = 3 Query: 291 FCYFEKPCVVPDSESQITISHESRLTIHNISSDNSGYYVCRVTLLTTSEHIISLA----VVTVKTPPKSISFHFNKSIN--VFQEQEFIAIQCSVSGGIPPPKISMYIVKDNAIKRLKIISSNFPNSTIAEVSAISLWRPHYLENRGFVMCTAINDAGVLTKNTSLLNIKY-----KPKIKPFVPNTVNAMINQTIDLSCEVYANPAATIQWVI-------MQGLQIIDSSKFIAKIRPDMDGPLICEAKNYLGSTKETVQLNVLRDPLIHID-SNYRVPKNSNYSINCRV--TSNPPPEFIKWYKLSNMTDSSAVLISDDAKLNFILIDRSSTGMYACVTQNIQISTTGKRKPANSEKTMFLTVTYKPKEPQILGNKI--ISIMKGEKFIIKCSTDRKSPGEPFPTLKWIDVETKDIV---------SDMETFQVINSESRHNGKYKCLAENEIGKSFSRETALVTVNEAPSIITQHKNRKVFLSYSDLPQSISFTCEFRGQPLYEARWRYGNEKIPPSSQDFKIEDHRNISNERISQIFTKLTIDLYSRTFSQQTSLRSSPNGRYNCEADNRHGIASLDYFLXXXXXXXXXXNIRHRKIAASLNQNVVMIRCQAESISTMHIKWYKTNEHIVLPFQSKKYSIFEAEVTKYEPERDLFTPGLKVNELTIKDLENDDFSNYSCVASNDQGIKKVNFEVVFKSQP 2306 + F+ + PDS + ++ L I +++G Y C +++ + A +V V PP HF K V + + + + C+ +P + + D +++ I S N V+ I L ++ GF CTA+N+AG+ K L+ I+ + K+ P + + + + L C P TI ++ + II S+ I + +++G C A+N G +++ + + VL P + + N V ++ C + TS + + + D A SD +KL + Y+C+ N A + +F P P+I G+ I+ I C T+ G P P + W ++ K I+ D+ + ++ N + G+Y C+AEN+ G++ + V ++E P ++ + +V + + CE G P W E P + D + Q TKL+ L+ R +T+L + G Y C A N+ G + + + PP I+ ++ N M+ CQ ++ W + + I + F P L I++ D YSC+ASN+ G +F + ++P Sbjct: 2701 YWLFDDKPLEPDSAAYELTNNGETLKIVRSQVEHAGTYTCE------AQNNVGKARKDFLVRVTAPP-----HFEKEREEVVARVGDTMLLTCNAESSVPLSSVYWH-AHDESVQNGVITSKYAANEKTLNVTNIQL------DDEGFYYCTAVNEAGITKKFFKLIVIETPYFLDQQKLYPII-------LGKRLTLDCSATGTPPPTILFMKDGKRLNESDEVDIIGSTLVIDNPQKEVEGRYTCIAENKAGRSEKDMMVEVLLPPKLSKEWINVEVQAGDPLTLECPIEDTSGVHITWSRQFGKDGQLDMRAQSSSDKSKLYIMQATPEDADSYSCIAVN----------DAGGAEAVFQVTVNTP--PKIFGDSFSTTEIVADTTLEIPCRTE----GIPPPEISWF-LDGKPILEMPGVTYKQGDL-SLRIDNIKPNQEGRYTCVAENKAGRA--EQDTYVEISEPPRVVMASEVMRVVEG-----RQTTIRCEVFGNPEPVVNWLKDGE---PYTSD-------------LLQFSTKLSY-LHLR----ETTL--ADGGTYTCIATNKAGESQTTTDVEVLVPPRIED---EERVLQGKEGNTYMVHCQVTGRPVPYVTWKRNGKEI-----------------------EQFNPVLH-----IRNATRADEGKYSCIASNEAGTAVADFLIDVFTKP 3300 HSP 5 Score: 80.1073 bits (196), Expect = 1.172e-14 Identity = 122/562 (21.71%), Postives = 225/562 (40.04%), Query Frame = 3 Query: 342 TISHESRLTIHNISSDNSGYYVCRVTLLTTSEHIISLAVVTVKTPPKSISFHFNKSINVFQEQEFIAIQCSVSGGIPPPKISMYIVKDNAIKRLKIISSNFPNSTIAEVSAISLWRPHYLENRGFVMCTAINDAGVLTKNTSLLNIKYKPKIKPFVPNTVNAMINQTIDLSCEVYANPAATIQWVIMQGLQI-IDSSKFIAKIRPDMDGPLI-------------CEAKNYLGSTKETVQLNVLRDPLIH---IDSNYRVPKNSNYSINCRVTSNPPPEFIKWYKLSN--MTDSSAVLISDDA-KLNFILIDRSSTGMYACVTQNIQISTTGKRKPANSEKTMFLTVTYKPKEPQILGNKIISIMKGEKFIIKCSTDRKSPGEPFPTLKWI----------DVETKDIVSDMETFQVINSESRHNGKYKCLAENEIGKSFSRETALVTVNEAPSIITQHKNRKVFLSYSDLPQSISFTCEFRGQPLYEARWRY---GNEKIPPSSQDFKIEDHRNISNERISQIFTKLTIDLYSRTFSQQTSLRSSPNGRYNCEADNRHGIA 1928 TI + L + N+ +N+G +VC+V+ L + + +TV PK IS ++V + I I C +G P I + N I LK+ F ++ + + ++ + G C N+AG ++ T+ ++++ P I P A++ ++L C V A+P A++ W +G+ I D+ ++ + DG L+ C+A N G + +Q+ V+ P I + + + ++ +S+ C V SNP P+ I WY + D ++ SDD KL+ + +G+Y CV +N K+ + V + K + +GE+ + C G P P + W+ + + +D T + + G Y C+A+++ G + L + A I+ + N +VFL + IS +C+ + + + + + G+E P + + HR LY T + NG+Y C N G A Sbjct: 1227 TIREDGALVLQNVKLENTGVFVCQVSNLAGEDSL--SYTLTVHEKPKIIS-EVPGVVDVVKGFT-IEIPCRATG--VPEVIRTW--NKNGID-LKMDEKKF---SVDNLGTLRIYEADK-NDIGNYNCVVTNEAGT-SQMTTHVDVQEPPIILPSTQTNNTAVVGDRVELKCYVEASPPASVTW-FRRGIAIGTDTKGYVV----ESDGTLVIQSASVEDATIYTCKASNPAGKAEANLQVTVIASPDIKDPDVVTQESIKESHPFSLYCPVFSNPLPQ-ISWYLNDKPLIDDKTSWKTSDDKRKLHVFKAKITDSGVYKCVARNAA---------GEGSKSFQVEVIVPLNLDESKYKKKVFAKEGEEVTLGCPVS----GFPVPQINWVVDGTVVEPGKKYKGATLSNDGLTLHFDSVSVKQEGNYHCVAQSK-GNILDIDVELSVL--AVPIVGEDDNLEVFLG-----KDISLSCDLQTESDDKTTFVWSINGSESDRPDNVQIPSDGHR-----------------LYI------TDAKPENNGKYMCRVTNSAGKA 1724 HSP 6 Score: 77.0258 bits (188), Expect = 1.139e-13 Identity = 148/650 (22.77%), Postives = 248/650 (38.15%), Query Frame = 3 Query: 516 VFQEQEFIAIQCSVSGG---IPPPKISMYIVKDNAI-----KRLKIISSNFPNSTIAEVSAISLWRPHYLENRGFVMCTAINDAGVLTKNTSLLNIKYKPKIKPFVPNTVNAMINQT--IDLSCEVYANPAATIQWVIMQGLQIIDSSKFIAKIRPDMD--------GPLICEAKNYLGSTKETVQLNVLRDPLIH---IDSNYRVPKNSNYSINCRVTSNPPPEFIKWYKLSNMTDSSAVLISDDAKLNFILIDRSST---GMYACVTQNIQISTTGKRKPANSEKTMFLTVTYKPKEPQILGNKIISIMKGEKFIIKCSTDRKSPGEPFPTLKWI-------DVETKDIVSDMETFQVINSESRHNGKYKCLAENEIGKS-FSRETALVTVNEAPSIITQHKNRKVFLSYSDLPQSISFTC------EFRGQPLYEARWRYGNEKIPPSSQDFKIEDHR--NISNERISQIFTKLTIDLYSRTFSQQTSLRSSPNGRYNCEADNRHGIASLDYFLXXXXXXXXXXNIRHRKIAASLNQNVVMIRCQAESISTMHIKWYKTNEHIVLPFQSKKYSIFEAEVTKYEPERDLFTPG-LKVNELTIKDLENDDFSNYSCVASNDQGIKKVNFEVVFKSQPDPPYDLRVTDFE 2342 +F+E E I + C VS G I K + + +++AI RL I+++N R H C A N AG ++K+ ++ ++ PKIK V V IN+ I L+C+ NP T +W QG + + F+ + G C A N +G +T+ ++V P +S V + ++ C V + I W + + A F+ I + T G YAC N + + KT L V P G ++++ ++ C G+P P + W D+++ ++S+ + F+++++E H G Y C+A+N++G + S + ++T P I KN + LP F C F+GQ + W + I D + ED R +SN+R +LTI ++ + G+Y+C N G S D F P + K ++ + V + C A I W+K E I + E D+ G L N+L I ++ D Y+C A N G + + V + P D +D+E Sbjct: 1837 IFRESETITLDCPVSLGDFQITWMKQGLPLTENDAIFTLDNTRLTILNAN---------------RDH----EDIYTCVANNTAGQVSKDFDVV-VQVLPKIKNAV---VTLEINEGEEIILTCDAEGNPTPTAKWDFNQG-DLPKEAVFVNNNHTVVVNNVTKYHTGVYKCYATNKVGQAVKTINVHVRTKPRFESGLTESELTVNLTRSITLECDV-DDAIGVGISWTVNGKPFLAETDGVQTLAGGRFLHIVSAKTDDHGSYACTVTN---------EAGVATKTFNLFVQVPPTIVNEGGE--YTVIENNSLVLPCEVT----GKPNPVVTWTKDGRPVGDLKSVQVLSEGQQFKIVHAEIAHKGSYICMAKNDVGTAEISFDVDIIT---RPMIQKGIKNIVTAIKGGALP----FKCPIDDDKNFKGQII----WLRNYQPI-----DLEAEDARITRLSNDR------RLTI----------LNVTENDEGQYSCRVKNDAGENSFD-FKATVLVPPTIIMLDKDKNKTAVEHSTVTLSCPATGKPEPDITWFKDGEAIHI-----------------ENIADIIPNGELNGNQLKITRIKEGDAGKYTCEADNSAGSVEQDVNVNVITIPKIEKDGIPSDYE 2396 HSP 7 Score: 76.2554 bits (186), Expect = 1.840e-13 Identity = 164/698 (23.50%), Postives = 263/698 (37.68%), Query Frame = 3 Query: 363 LTIHNISSDNSGYYVCRVTLLTTSEHIISLA--VVTVKTPPKSISFHFNKSINVFQEQEFIAIQCSVSGGIPPPKISMYIVKDNAIKRLKIISSNFPNSTIAEVSAISLWRPHYLENRGFVMCTAINDAGVLTKNTSLLNIKYKPKIKPFVPNTVNAMINQTIDLSCEVYANPAATIQWVIMQGLQIIDSSKFIA--------KIRPDMDGPLICEAKNYLGSTKETVQLNVLRDP-LIHIDSN-YRVPKNSNYSINCRVTSNPPPEFIKWY----------KLSNMTDSSAVLISDDAKLNFILIDRSSTGMYACVTQNIQISTTGKRKPANSEKTMFLTVTYKPK--EPQILGNKIISIMKGEKFIIKCSTDRKSPGEPFPTLKW----IDVETKD----IVSDMETFQVINSESRHNGKYKCLAENEIGKSFSRETALVTVNEAPSIITQHKNRKVFLSYSDLPQSISFTCEFR-----GQPLYEARWRYGNEKIPPSSQDFKIEDHRNISNERISQIFTKLTIDLYSRTFSQQTSLRSSPNGRYNCEADNRHGIASLDYFLXXXXXXXXXXNIRHRK---IAASLNQNVVMIRCQAES----------ISTMHIK-WYKTNEHIVL-------PFQSKKYSIFEAEVTKYEPERDLFTPGLKVNELTIKDLENDDFSNYSCVASNDQGIKKVNF 2282 L I N + + G Y C + ++E ++A ++ V T P +F +++ E E I+C + G P P IS ++ II S ++ + + + + G C A N G ++ + N+ KP I + T A+ I L C V NP T+ W DS I + + G C A N G+ V+ P + N Y V +N +++C VTS P P I W+ + S D S + I + AKL S G Y C N + S+ + L + PK + I+GN + + + ++C G P P + W +D+ D + + ETF + N + G+Y C A N GK+ S + +L + +P H + D +I+ TC + + + W ++D + D N IS KLTI Q SL ++ G Y C A NR G ASL++ + I + R + IA + V R ++S IS ++ N+ ++ PF S K+ EVT E R + G L I ++D +SCVA ND G+K++ Sbjct: 3264 LHIRNATRADEGKYSC----IASNEAGTAVADFLIDVFTKP---TFETHETTFNIVEGESAKIECKIDGH-PKPTIS-WLKGGRPFNMDNIILSPRGDT-------LMILKAQRFDG-GLYTCVATNSYGDSEQDFKV-NVYTKPYIDETIDQTPKAVAGGEIILKCPVLGNPTPTVTWKRGDDAVPNDSRHTIVNNYDLKINSVTTEDAGQYSCIAVNEAGNLTTHYAAEVIGKPTFVRKGGNLYEVIENDTITMDCGVTSRPLPS-ISWFRGDKPVYLYDRYSISPDGSHITI-NKAKL-------SDGGKYICRASN---------EAGTSDIDLILKILVPPKIDKSNIIGNPLAIVAR--TIYLECPIS----GIPQPDVIWTKNGMDINMTDSRVILAQNNETFGIENVQVTDQGRYTCTATNRGGKA-SHDFSLDVL--SPPEFDIHGTQPTIKREGD---TITLTCPIKLAEDIADQVMDVSW----------TKDSRALDGDLTDNVDISDDGRKLTI--------SQASLENA--GLYTCIALNRAGEASLEFKVEILCTSLATVKCREHENNYIARHMPHVVTKPREMSQSANAYPPPVIDISRNDVQPQVAVNQPTIMRCAVTGHPFPSIKWLKNGKEVTDDENIR-IVEQG---QVLQILRTDSDHAGKWSCVAENDAGVKELEM 3889 HSP 8 Score: 75.485 bits (184), Expect = 3.262e-13 Identity = 136/594 (22.90%), Postives = 221/594 (37.21%), Query Frame = 3 Query: 330 ESQITISHESRLTIHNISSDNSGYYVCRVTLLTTSEHIISLAVVTVKTPPKSISFHFNKSINVFQ--EQEFIAIQCSVSGGIPPPKISMYIVKDNAIKRLKIISSNFPNSTIAEVSAISLWRPHYLENRGFVMCTAINDAGVLTKNTSL-LNIKYKPKI-KPFVPNTVNAMINQTIDLSCEVYANPAATIQWVIMQGLQI--IDSSKFIAK---------IRPDMDGPLICEAKNYLGSTKETVQLNVLRDPLIHIDSNYRVPKNSNYSINCRVTSNPPPEF------IKWYKLSNMTDSSA---VLISDDA-KLNFILIDRSSTGMYACVTQN---------------IQISTTGKRKPANSEKTMFLT-VTYKPKEPQILGNK----IISIMKG---------EKFIIKCSTDRKSPGEPFPTLKWI-------DVETKDIVSDMETFQVINSESRHNGKYKCLAENEIGKSFSRETALVTVNEAPSIITQHKNRKVFLSYSDLPQSISFTCEFRGQPLYEARWRYGNEKIPPSSQDFKIEDHRNISNERISQIFTKLTIDLYSRTFSQQTSLRSSPNGRYNCEADNRHGIA 1928 +S+ TI + L I++++++++G Y C + + A + P K N+++ E + I + C V+ P P IS + D + S + S I A L + G +C A N+AG T + L L I PKI K + A++ +TI L C + P + W G+ I DS +A+ ++ G C A N G L+VL P I K +I + + W K S D V ISDD KL + G+Y C+ N ++T R+ N+ + V KP+E N +I I + + I++C+ G PFP++KW+ D E IV + Q++ ++S H GK+ C+AEN+ G +E +V P +++ + + L ++I+ C G P + +W G I F D RIS +L I L+ + G Y C+A N G + Sbjct: 3434 DSRHTIVNNYDLKINSVTTEDAGQYSC-IAVNEAGNLTTHYAAEVIGKP-----TFVRKGGNLYEVIENDTITMDCGVTSR-PLPSIS-WFRGDKPVYLYDRYSISPDGSHITINKA-------KLSDGGKYICRASNEAG--TSDIDLILKILVPPKIDKSNIIGNPLAIVARTIYLECPISGIPQPDVIWT-KNGMDINMTDSRVILAQNNETFGIENVQVTDQGRYTCTATNRGGKASHDFSLDVLSPPEFDIHGTQPTIKREGDTITLTCPIKLAEDIADQVMDVSWTKDSRALDGDLTDNVDISDDGRKLTISQASLENAGLYTCIALNRAGEASLEFKVEILCTSLATVKCREHENNYIARHMPHVVTKPREMSQSANAYPPPVIDISRNDVQPQVAVNQPTIMRCAVT----GHPFPSIKWLKNGKEVTDDENIRIVEQGQVLQILRTDSDHAGKWSCVAENDAG---VKELEMVLDVFTPPVVSVKSDNPI----KALGETITLFCNASGNPYPQLKWAKGGSLI------FDSPD-----GARISLKGARLDI----------PHLKKTDVGDYTCQALNAAGTS 3977 HSP 9 Score: 71.633 bits (174), Expect = 3.909e-12 Identity = 137/614 (22.31%), Postives = 240/614 (39.09%), Query Frame = 3 Query: 318 VPDSESQITISHESRLTIHNISSDNSGYYVCRVTLLTTSEHIISLAVVTVKTPPKSISFHFNKSINVFQEQEFIAIQCSVSGGIPPPKISMYIVKDNAIKRLKIISSNFPNSTIAEVSAISLWRPHYLE-NRGFVMCTAINDAGVLTKNTSLLNIKYKPKI-KPFVPNTVNAMINQTIDLSCEVYANPAATIQWVI--------MQGLQIIDSSKFIA--KIRPDMDGPLICEAKNYLGSTKETVQLNVLRDPLIHIDSNYRVPKNSNYSINCRVTSNPPPEFIKWYKLSNMTDSS--AVLISDDAKLNFILIDRS-STGMYACVTQNIQISTTGKRKPANSEKTMFLTVTYKPKEPQILGN--KIISIMKGEKFIIKCSTDRKSPGEPFPTLKWI-------DVETKDIVSDMETFQVINSESRHNGKYKCLAENEIGKSFSRETALVTVNEAPSIITQHKNRKVFLSYSDLPQSISFTCEFRGQPLYEARWRYGNEKIPPSSQDFKIEDHRNISNERISQIFTKLTIDLYSRTFSQQTSLRSSPNGRYNCEADNRHGIASLDYFLXXXXXXXXXXNIRHRKIAASLNQNVVMIRCQAESISTMHIKWYKTNE 2087 V D E+ + L I SD++G + C + + L +V P +S + I E I + C+ SG P P++ K ++ I S P+ + L PH + + G C A+N AG + S+ ++ P+I + + + Q++ L C P ++W + G+ + S FI + G C A+N GS ++V++ P+I +V + I C V P P+ + W + N ++ V D ++ I+ RS +G+Y C S T + A T+ + V+ P+I+ + +++ G KF + C+ G P P + W D E + T + +E RH Y+C A+N+ G + E + T+ AP I T NR +++ S+ +++ CE + + + G +P ++ F ED++ I + S R S G Y+C A N+ G A+ L + P I R + + + V + C+A + I WYK NE Sbjct: 3846 VTDDENIRIVEQGQVLQILRTDSDHAGKWSC---VAENDAGVKELEMVLDVFTPPVVSVKSDNPIKALGET--ITLFCNASGN-PYPQLKW--AKGGSL----IFDS--PDGARISLKGARLDIPHLKKTDVGDYTCQALNAAGTSEASVSV-DVLVPPEINRDGIDMSPRLPAQQSLTLQCLAQGKPVPQMRWTLNGTALTHSTPGITVASDSTFIQINNVSLSDKGVYTCYAENVAGSDNLMYNVDVVQAPVISNGGTKQVIEGELAVIECLVEGYPAPQ-VSWLRNGNRVETGVQGVRYVTDGRMLTIIEARSLDSGIYLC-------SATNEAGSAQQAYTLEVLVS-----PKIITSTPGVLTPSSGSKFSLPCAVR----GYPDPIISWTLNGNDIKDGENGHTIGADGTLHIEKAEERHL-IYECTAKNDAGAD-TLEFPVQTI-VAPKISTS-GNR--YINGSEGTETV-IKCEIESESSEFSWSKNGVPLLPSNNLIFS-EDYKLI----------------------KILSTRLSDQGEYSCTAANKAGNATQKTNLNVGVAPKIMERPRTQVVHKG---DQVTLWCEASGVPQPAITWYKDNE 4394 HSP 10 Score: 71.633 bits (174), Expect = 4.825e-12 Identity = 118/555 (21.26%), Postives = 210/555 (37.84%), Query Frame = 3 Query: 705 NRGFVMCTAINDAGVLTKNTSLLNIKYKPKIKPFVPNTVNAMINQTIDLSCEVYANPAATIQWVIMQGLQIIDSSKFIAKIRPD---------MDGPL-ICEAKNYLGSTKETVQLNVLRDPLIH--IDSNYRVPKNSNYSINCRVTSNPPPEFIKWYKLSNMT--DSSAVLISD-DAKLNFILIDRSSTGMYACVTQNIQISTTGKRKPANSEKTMFLTVTYKPKEPQILGNKIISIMKGEKFIIKCSTDRKSPGEPFPTLKWIDVETK-------DIVSDMETFQVINSESRHNGKYKCLAENEIGKSFSRETALVTVNEAPSIITQHKNRKVFLSYSDLPQSISFTCEFRGQPLYEARWRYGNEKIPPSSQDFKIEDHRNISNERISQIFTKLTIDLYSRTFSQQTSLRSSPNGRYNCEADNRHGIASLDYFLXXXXXXXXXXNIRHRKIAASLNQNVVMIRCQ---AESIS--TMHIKWYKTNEHIVLPFQSKKYSIFEAEVTKYEPERDLFTPGLKVNELTIKDLENDDFSNYSCVASNDQGIKKVNFEV 2288 + G C A N+AG + L+++ KP + T N + ++ + C++ +P TI W ++G + + I R D DG L C A N G +++ ++NV P I ID + + C V NP P + W + + DS ++++ D K+N + + + G Y+C+ N + N V KP + GN + +++ + + C + P P++ W + I D + ++ GKY C A NE G S + L+ P I K+ + + + ++I C G P + W + D + D R I + + TF + +++ + GRY C A NR G AS D+ L +++I + + + + C AE I+ M + W +K + ++T D+ G K LTI ++ Y+C+A N G + F+V Sbjct: 3273 DEGKYSCIASNEAGTAVADF-LIDVFTKPTFETH-ETTFNIVEGESAKIECKIDGHPKPTISW--LKGGRPFNMDNIILSPRGDTLMILKAQRFDGGLYTCVATNSYGDSEQDFKVNVYTKPYIDETIDQTPKAVAGGEIILKCPVLGNPTPT-VTWKRGDDAVPNDSRHTIVNNYDLKINSVTTEDA--GQYSCIAVN---------EAGNLTTHYAAEVIGKPTFVRKGGN-LYEVIENDTITMDCGVTSR----PLPSISWFRGDKPVYLYDRYSISPDGSHITINKAKLSDGGKYICRASNEAGTS---DIDLILKILVPPKI--DKSNIIGNPLAIVARTIYLECPISGIPQPDVIWTK-------NGMDINMTDSRVILAQN-------------NETFGIE-NVQVTDQGRYTCTATNRGGKASHDFSL--DVLSPPEFDIHGTQPTIKREGDTITLTCPIKLAEDIADQVMDVSW------------TKDSRALDGDLTD---NVDISDDGRK---LTISQASLENAGLYTCIALNRAGEASLEFKV 3760 HSP 11 Score: 70.0922 bits (170), Expect = 1.120e-11 Identity = 144/689 (20.90%), Postives = 249/689 (36.14%), Query Frame = 3 Query: 330 ESQITISHESRLTIHNISSDNSGYYVCRVTLLTTSEHIISLAVVTVKTPPKSISFHFNKSINVFQEQEFIAIQCSVSGGIPPPKISMYIVKDNAIKRLKIISSNFPNSTIAEVSAISLWRPHYLENRGFVMCTAINDAGVLTKNTSLLNIKYKPKIK-PFVPNTVNAMINQTIDLSCEVYANPAATIQWVIMQGLQIIDSSKF----------IAKIRPDMDGPLICEAKNYLGSTKETVQLNVLRDPLIHIDSNYR----VPKNSNYSINCRVTSNPPPEFIKWYKLSNMTD-----SSAVLISDDAKLNFILIDRSSTGMYACVTQNIQISTTGKRKPANSEKTMFLTVTYKPKEPQILGNKIISIMKGEKFIIKCSTDRKSPGEPFPTLKW-IDVETKD------IVSDMETFQVINSESRHNGKYKCLAENEIGKSFSRETALVTVNEAPSIITQ--HKNRKVFLSYSDLPQSISFTCEFRGQPLYEARWRYGNEKIPPSSQDFKIEDHRNISNERISQI-FTKLTIDLYSRTFSQQTSLRSSPNGRYNCEADNRHGIASLDYFLXXXXXXXXXXNIRHRKIAASLNQNVVMIRCQAESISTMHIKWYKTNEHIVLPFQSKKYSIFEAEVTKYEPERDLFTPGLKVNELTIKDLENDDFSNYSCVASNDQGIKKVNFEVVFKSQP 2306 E + ++ + L I+ ++ G Y C VT + + + V V+ PP I ++ N + + ++C V PP ++ + R I + E + + +E+ C A N AG N + I P IK P V + + L C V++NP I W + I D + + + K + G C A+N G ++ Q+ V+ PL +S Y+ + ++ C V+ P P+ I W + + A L +D L+F + G Y CV Q + G + E ++ P + + + + G+ + C D ++ + T W I+ D I SD + +++ +NGKY C N GK+ T + V E P + N+K+ + I C+ G P W+ + D + +E +S + KLT + + +C A+N+ G AS D+F+ P K I + + C S+ I W K LP ++ +IF + T+ LTI + D Y+CVA+N G +F+VV + P Sbjct: 1315 EKKFSVDNLGTLRIYEADKNDIGNYNCVVTNEAGTSQMTTH--VDVQEPP--IILPSTQTNNTAVVGDRVELKCYVEAS-PPASVTWF--------RRGIAIGTDTKGYVVESDGTLVIQSASVEDATIYTCKASNPAGKAEANLQVTVIA-SPDIKDPDVVTQESIKESHPFSLYCPVFSNPLPQISWYLNDKPLIDDKTSWKTSDDKRKLHVFKAKITDSGVYKCVARNAAGEGSKSFQVEVIV-PLNLDESKYKKKVFAKEGEEVTLGCPVSGFPVPQ-INWVVDGTVVEPGKKYKGATLSNDGLTLHFDSVSVKQEGNYHCVAQ-----SKGNILDIDVELSVLAV-------PIVGEDDNLEVFLGKDISLSC--DLQTESDDKTTFVWSINGSESDRPDNVQIPSDGHRLYITDAKPENNGKYMCRVTNSAGKA--ERTLTLDVLEPPVFVEPVFEANQKLIGN-----NPIILQCQVTGNPKPTVIWKIDGNDV----------DKSWLFDESLSLLRIEKLT----------------GKSAQISCTAENKAGTASRDFFIQNIAAPTFKNEGDQETIFRE--SETITLDCPV-SLGDFQITWMKQG----LPL-TENDAIFTLDNTR----------------LTILNANRDHEDIYTCVANNTAGQVSKDFDVVVQVLP 1916 HSP 12 Score: 67.3958 bits (163), Expect = 7.957e-11 Identity = 115/559 (20.57%), Postives = 209/559 (37.39%), Query Frame = 3 Query: 702 ENRGFVMCTAINDAGVLTKNTSLLNIKYKPKIKPFVPNTVNAMINQTIDLSCEVYANPAATIQWVI----MQGLQIIDSSKFIAKIRP--DMDGPLICEAKNYLGSTKETVQLNVLRDPLIHIDSNYRV--PKNSNYSINCRVTSNPPPEF-IKWYKLS-NMTDSSAVLISDDAKLNFILIDRSSTGMYACVTQNIQISTTGKRKPANSEKTMFLTVTYKPKEPQILGNKIIS--IMKGEKFIIKCSTDRKSPGEPFPTLKWIDVETKDIVSDM------ETFQVINSESRHNGKYKCLAENEIGKSFSRETALVTVNEAPSIITQHKNRKVFLSYSDLPQSISFTCEFRGQPLYEARWRYGNEKIPPSSQDFKIEDHRNISNERISQIFTKLTIDLYSRTFSQQTSLRSSPNGRYNCEADNRHGIASLDYFLXXXXXXXXXXNIRHRKIAASLNQNVVMIRCQAESISTMHIKWYKTN------EHIVLPFQSKKYSIFEAEVTKYEPERDLFTPGLKVNELTIKDLENDDFSNYSCVASNDQGIKKVNFEVVFKSQP 2306 EN G MC N AG + +L ++ ++P + N I L C+V NP T+ W I + + D S + +I + C A+N G+ + + P + + ++ +++C V+ +F I W K +T++ A+ D+ +L + +R +Y CV N T G+ K + V PK + N +++ I +GE+ I+ C + G P PT KW D D+ + T V N H G YKC A N++G++ +T V V P + ++ + +L +SI+ C+ W + + F E T L F S ++ +G Y C N G+A+ + L ++ PP I + + N +++ C+ + W K + + + + +++ I AE+ +Y C+A ND G +++F+V ++P Sbjct: 1708 ENNGKYMCRVTNSAGKAERTLTLDVLEPPVFVEPVFEANQKLIGNNPIILQCQVTGNPKPTVIWKIDGNDVDKSWLFDESLSLLRIEKLTGKSAQISCTAENKAGTASRDFFIQNIAAPTFKNEGDQETIFRESETITLDCPVSLG---DFQITWMKQGLPLTENDAIFTLDNTRLTILNANRDHEDIYTCVANN----TAGQ-----VSKDFDVVVQVLPK----IKNAVVTLEINEGEEIILTCDAE----GNPTPTAKW-DFNQGDLPKEAVFVNNNHTVVVNNVTKYHTGVYKCYATNKVGQAV--KTINVHVRTKPRFESGLTESELTV---NLTRSITLECDVDDAIGVGISWTV-------NGKPFLAE--------------TDGVQTLAGGRFLHIVSAKTDDHGSYACTVTNEAGVATKTFNLFVQVPPTIVNEGGEYTV---IENNSLVLPCEVTGKPNPVVTWTKDGRPVGDLKSVQVLSEGQQFKIVHAEIAHK--------------------------GSYICMAKNDVGTAEISFDVDIITRP 2190 HSP 13 Score: 63.929 bits (154), Expect = 1.081e-9 Identity = 127/631 (20.13%), Postives = 239/631 (37.88%), Query Frame = 3 Query: 525 EQEFIAIQCSVSGGIPPPKISMYIVKDNAIKRLKIISSNFPNSTIAEVSAISLWRPHYLENRGFVMCTAINDAGVLTKNTSLLNIK-----YKPKIKPFVPNTVNAM-------INQTID--------LSCEVYANPAATIQWVIMQGLQII----------DSSKFIAKIRPDMDGPLICEAKNYLGSTKETVQLNVLRDPLIH-IDSNYRVPKNSNYSINCRVTSNPPPEFIKWYKLSNMTDSSAVLISDDAKLNFILIDRSSTGMYACVTQNIQISTTGKRKPANSEKTMFLTVTYKPKEPQILGNKIISIMKGEKFIIKCSTDRKSPGEPFPTLKWIDVETKDI---VSDMETFQVINSESRHNGKYKCLAENEIGKSFSRETALVTVNEAPSIITQHKNR-KVFLSYSDLPQSISFTCEFRGQPLYEARWRYGNEKIPPSSQDFKIEDHR-NISNERISQIFTKLTIDLYSRTFSQQTSLRSSPNGRYNCEADNRHGIASLDYFLXXXXXXXXXXNIRHRKIAASLNQNVVMIRCQAESISTMHIKWYKTNEHIVLPFQSKKYSIFEAEVTKYEPERDLFTPGLKVNELTIKDLENDDFSNYSCVASNDQGIKKVNFEVVFKSQPD 2309 E + + + C V G P P I ++I D ++ P I ++ R ++ G C A++ AG T + ++ IK YKP+ T++ M +N T D + C V P I W + G I D++ + K G C+A N G ++ + ++ P+I S++ + + ++I C V +P P I W L + + ++++D L ++ + G + C QN N +T+ LTV P KI ++ + +++C P T + ++++ I + + + N + + G + C N G+ T +TV+E P II++ V ++ I C G P W + D K+++ + ++ N +I+ D+ G YNC N G + + + ++ PPII + + A ++ V ++C E+ + W++ I + +K Y + E++ T L I+ +D + Y+C ASN G + N +V + PD Sbjct: 900 EGQDLTLSCVVVLGTPKPSI-VWIKDDKPVEE-------GPTIKIEGGGSLLRLRGGNPKDEGKYTCIAVSPAGNSTLHINVQLIKKPEFVYKPEGGIVFKPTISGMDEKHVAVVNSTHDVLDGEGFAIPCVVSGTPPPIITWY-LDGRPITPNSRDFTVTADNTLIVRKADKSYSGVYTCQATNSAGDNEQKTTIRIMNTPMISPGQSSFNMVVDDLFTIPCDVYGDPKP-VITW--LLDDKPFTEGVVNEDGSLTIPNVNEAHRGTFTCHAQNAA---------GNDTRTVTLTVHTTPTINAENQEKIA--LQNDDIVLECPAKALPPPVRLWTYEGEKIDSQLIPHTIREDGALVLQNVKLENTGVFVCQVSNLAGEDSLSYT--LTVHEKPKIISEVPGVVDVVKGFT-----IEIPCRATGVPEVIRTWNK-------NGIDLKMDEKKFSVDNLGTLRIYEADKNDI----------------GNYNCVVTNEAGTSQMTTHVDVQEPPIILPSTQTNNTAVVGDR--VELKCYVEASPPASVTWFRRG--IAIGTDTKGY-VVESDGT-----------------LVIQSASVEDATIYTCKASNPAGKAEANLQVTVIASPD 1455 HSP 14 Score: 61.6178 bits (148), Expect = 4.958e-9 Identity = 132/640 (20.62%), Postives = 233/640 (36.41%), Query Frame = 3 Query: 153 ITPNNATVNSKENLTLECVVDQQ-NIVYSWEY--KPFHIKSNIMSKVLGFCYFEKPCVVPDSESQITISHESRLTIHNISSDNSGYYVCRVTLLTTSEHIISLAV--VTVKTPPKSISFHFNKSINVFQEQEFIAIQCSVSGGIPPPKISMYIVKDNAIKRLKIISSNFPNSTIAEVSAISLWRPHYLENRGFVMCTAINDAGVLTKNTSL-LNIKYKPKIKPFVPNTVNAMINQTIDLSCEVYANPAATIQWVIMQGLQIIDSSKFIAKI--------------RPDMDGPLICEAKNYLGSTKETVQLNVLRDPLIHI---DSNYRVPKNSNYSINCRVTSNPPPEFIKWYKLSNMTDSSAVLISDDA-----------KLNFILIDRSSTGMYACVTQNIQISTTGKRKPANSEKTMFLTVTYKPKEPQILGNKIISIMKGEKFIIKCSTDRKSP--------GEPFPTLKWIDVETKDIVSDMETFQVINSESRHNGKYKCLAENEIGKSFSRETALVTVNEAPSIITQHKNRKVFLSYSDLPQSISFTCEFRGQPLYEARWRYGNEKIPPSSQDFKIEDHRNISNERISQIFTKLTIDLYSRTFSQQTSLRSSPNGRYNCEADNRHGIASLDYFL 1946 +T + TVN ++TLEC VD + SW KPF +++ + + G + L I + +D+ G Y C V T+E ++ + V+ PP ++ ++ E + + C V+G P + + + LK + ++E + + ++G +C A ND G T S ++I +P I+ + N V A+ + C + + Q + ++ Q ID A+I + +G C KN G + VL P I + D N ++S +++C T P P+ I W+K D A+ I + A +L I G Y C N + E+ + + V PK + + E+ +I C + P G+P + K+ V+T + F++ ++S KY C+A NE G + V++ APS + R++ ++ + P ++ C +G P W I P+ + + R + Q + S GRY C A N G L+ L Sbjct: 2011 LTESELTVNLTRSITLECDVDDAIGVGISWTVNGKPFLAETDGVQTLAGGRF---------------------LHIVSAKTDDHGSYACTV----TNEAGVATKTFNLFVQVPPTIVNEGGEYTV---IENNSLVLPCEVTG--KPNPVVTWTKDGRPVGDLKSV------QVLSEGQQFKIVHAE-IAHKGSYICMAKNDVG--TAEISFDVDIITRPMIQKGIKNIVTAIKGGALPFKCPIDDDKNFKGQIIWLRNYQPIDLEAEDARITRLSNDRRLTILNVTENDEGQYSCRVKNDAGENSFDFKATVLVPPTIIMLDKDKNKTAVEHSTVTLSCPATGKPEPD-ITWFK-----DGEAIHIENIADIIPNGELNGNQLKITRIKEGDAGKYTCEADN---------SAGSVEQDVNVNVITIPKIEKDGIPSDYESQQNERVVISCPVYARPPAKITWLKAGKPLQSDKF--VKTSANGQKLYLFKLRETDSS---KYTCIATNEAGT--DKRDFKVSMLVAPSFDEPNIVRRITVNSGN-PSTLH--CPAKGSPSPTITWLKDGNAIEPNDRYVFFDAGRQL----------------------QISKTEGSDQGRYTCIATNSVGSDDLENTL 2564 HSP 15 Score: 55.4546 bits (132), Expect = 3.357e-7 Identity = 65/315 (20.63%), Postives = 121/315 (38.41%), Query Frame = 3 Query: 357 SRLTIHNISSDNSGYYVCRVTLLTTSEHIISLAVVTVKTPPKSISFHFNKSINV-FQEQEFIAIQCSVSGGIPPPKISMYIVKDNAIKRLKIISSNFPNSTIAEVSAISLWRPHYL--ENRGFVMCTAINDAGVLTKNTSLLNIKYKPKIKPFVPNTVNAMINQTIDLSCEVYANPAATIQWVIMQ-------GLQIIDSSKF--IAKIRPDMDGPLICEAKNYLGSTKETVQLNVLRDPLIHIDSN-YRVPKNSNYSINCRVTSNPPPEFIKWYK-LSNMTDSSAVLISDDAKLNFILIDRSSTGMYACVTQNI 1259 S TI +S ++G Y CRV + + + V T ++PP+ ++++V E F+ +G + I+ + ++ F + H++ + G C A N G+ T+ L +I P +K P V + + ++LSCE +P + W Q+ SKF I +G C A + G ++T L + P + I N V + S C+ P I+W+K ++ + ++ +L+ + G Y+CV +N+ Sbjct: 482 SVWTIPELSLKDAGEYECRV-ISNNGNYSVKTRVETRESPPEIFGV---RNVSVPLGEAAFLHCSTRSAGEV-------------EIRWTRYGATVFNGPNTERNPTNGTLKIHHVTRADAGVYECMARNAGGMSTRKMRL-DIMEPPSVK-VTPQDVYFNMREGVNLSCEAMGDPKPEVHWYFKGRHLLNDYKYQVGQDSKFLYIRDATHHDEGTYECRAMSQAGQARDTTDLMLATPPKVEIIQNKMMVGRGDRVSFECKTIRGKPHPKIRWFKNGKDLIKPDDYIKINEGQLHIMGAKDEDAGAYSCVGENM 777 HSP 16 Score: 54.6842 bits (130), Expect = 5.656e-7 Identity = 96/423 (22.70%), Postives = 164/423 (38.77%), Query Frame = 3 Query: 516 VFQEQEFIAIQCSVSGGIPPPKISMYIVKDNAIKRLKIISSNFPNSTIAEVSAISLWRPHYLENRGFVMCTAINDAGVLTKNTSLLNIKYKPKIKPFVPNTVNAMIN--QTIDLSCEVYANPAATIQWVIMQGL--------QIIDSSKFIAKIRPDMDGPLICEAKNYLGSTKETVQLNV----LRDPLIHIDSNYRV-PKNSNYSINCRVTSNPPPEFIKWYKLSNMTDSSAVLISDDAKLNFILIDRSSTGMYACVTQNIQISTTGKRKPANSEKTMFLTVTYKPKEPQ-ILGNKIISIMKGEKFIIKCSTDRKSPGEPFPTLKWID----VETKDIVSDMETFQVINSESRHNGKYKCLAENEIGKSFSRETALVTVNE----APSIITQHKNRKVFLSYS-DLPQSISFTCEFRGQPL 1709 V + + + + C SG +P P I+ Y KDN +++++ + T ++ G C A N ++ L+ + P++ VP +N N QT+ LSC P I W+ + QI+ ++ I + PD DG C AK+ G T +L V R I ++ + + PK + Y I+ T + P+ + W + +D+ LN + Y C+ G R S +T+ L PQ I+ K + G ++CS + G P PT+ W +E +V + + +G+Y C+A+N +G S +A + V+ P + KN V Y + S T E+ G P+ Sbjct: 4366 VVHKGDQVTLWCEASG-VPQPAITWY--KDN-----ELLTNTGVDETATTKKKSVIFSSISPSQAGVYTCKAENWVASTEEDIDLI-VMIPPEV---VPERMNVSTNPRQTVFLSCNATGIPEPVISWMRDSNIAIQNNEKYQILGTTLAIRNVLPDDDGFYHCIAKSDAGQKIATRKLIVNKPSDRPAPIWVECDEKGKPKKTEYMIDRGDTPDDNPQLLPWKDV------------EDSSLNGSI-------AYRCM--------PGPR----SSRTVLLHAA-----PQFIVKPKNTTAAIGAIVELRCS----AAGPPHPTITWAKDGKLIEDSKFEIAYSHLKVTLNSTSDSGEYTCMAQNSVGSSTV--SAFINVDNNILPTPKPSSNQKNVAVITCYERNQAYSRGLTWEYNGVPM 4734
BLAST of hemicentin-1 isoform X2 vs. Ensembl Celegans
Match: him-4 (High Incidence of Males (Increased X chromosome loss) [Source:UniProtKB/TrEMBL;Acc:A4UVK0]) HSP 1 Score: 104.375 bits (259), Expect = 5.534e-22 Identity = 157/706 (22.24%), Postives = 278/706 (39.38%), Query Frame = 3 Query: 306 KPCVVPDSESQIT-ISHESRLTIHNISSDNSGYYVCRVTLLTTSEHIISLAVVTVKTPPKSISFHFNKSINVFQEQEFIAIQCSVSGGIPPPKISMYIVKDNAIKRLKIISSNFPNSTIAEVSAISLWRPHYLE-NRGFVMCTAINDAGVLTKNTSLLNIKYKPKI-KPFVPNTVNAMINQTIDLSCEVYANPAATIQWVIMQGLQIIDSSKFIA-----------KIRPDMDGPLICEAKNYLGSTKETVQLNVLRDPLI---HIDSNYRVPKNSNYSINCRVTSNPPPEFIKWYKLSNMTDSSAVLISDDA--KLNFILIDRSSTGMYACVTQNIQISTTGKRKPANSEKTMFLTVTYKPKEPQILGNKIISIMKGEKFIIKCSTDRKSPGEPFPTLKWIDVE-TKD----------------IVSDMETFQVINSESRHNGKYKCLAENEIGKSFSRETALVTVNEAPSIITQ--HKNRKVFLSYSDLPQSISFTCEFRGQPLYEARWRYGNEKIPPSSQDFKIEDHRNISNERISQIFTKLTIDLYSRTFSQQTSLRSSPNGRYNCEADNRHGIASLDYFLXXXXXXXXXXNIRHRKIAASLNQNVVMIRCQAE-SISTMHIKWYKTNEHIVLPFQSKKYSIFEAEVTKYEPERDLFTPGLKVNELTIKDLENDDFSNYSCVASNDQGIKKVNFEVVFKSQP 2306 +P + +++IT +S++ RLTI N++ ++ G Y CRV A V V PP I +K+ E + + C +G P P I+ + KD ++ I+ PN E++ L E + G C A N AG + ++ ++ N+ PKI K +P+ + N+ + +SC VYA P A I W ++ + + S KF+ K+R C A N G+ K ++++L P +I V + +++C +P P I W K N + + + DA +L + S G Y C+ N + G N+ + + P I G + ++ E F + D S G +DVE KD I S + +++ +G+Y C+ N G+ +R+ VN+ PSI + N + + Y + C G P + W + ++ + P S +++ ++ SQ+ G Y CEA N G A D+ + + PP + + R+ + + +++ C AE S+ + W+ +E + + KY+ E L + +++ DD Y C A N+ GI K F+++ P Sbjct: 2231 QPIDLEAEDARITRLSNDRRLTILNVTENDEGQYSCRVKNDAGENSFDFKATVLV--PPTIIMLDKDKNKTAV-EHSTVTLSCPATGK-PEPDITWF--KDGEAIHIENIADIIPN---GELNGNQLKITRIKEGDAGKYTCEADNSAGSVEQDVNV-NVITIPKIEKDGIPSDYESQQNERVVISCPVYARPPAKITW--LKAGKPLQSDKFVKTSANGQKLYLFKLRETDSSKYTCIATNEAGTDKRDFKVSMLVAPSFDEPNIVRRITVNSGNPSTLHCPAKGSPSPT-ITWLKDGNAIEPNDRYVFFDAGRQLQISKTEGSDQGRYTCIATN----SVGSDDLENTLEVII--------PPVIDGERREAVAVIEGFSSELFCDSNSTG--------VDVEWQKDGLTINQDTLRGDSFIQIPSSGKKMSFLSARKSDSGRYTCIVRNPAGE--ARKLFDFAVNDPPSISDELSSANIQTIVPY----YPVEINCVVSGSPHPKVYWLFDDKPLEPDSAAYELTNNGETLKIVRSQV---------------------EHAGTYTCEAQNNVGKARKDFLVRVTAPPHFE---KEREEVVARVGDTMLLTCNAESSVPLSSVYWHAHDESVQNGVITSKYAANE-------------------KTLNVTNIQLDDEGFYYCTAVNEAGITKKFFKLIVIETP 2854 HSP 2 Score: 94.3597 bits (233), Expect = 5.416e-19 Identity = 148/706 (20.96%), Postives = 273/706 (38.67%), Query Frame = 3 Query: 306 KPCVVPDSESQITISHESRLTIHNISSDNSGYYVCRVTLLTTSEHIISLAVVTVKTPPKSISFHFNKSINVFQEQEFIAIQCSVSGGIPPPKISMYIVKDNAIKRLKIISSNFPNSTIAEVSAISLW-RPHYLENRGFVMCTAINDAGVLTKNTSLLNIKYKPKIKPFVPNTVNAMINQTIDLSCEV-YANPAATIQWV-----IMQGLQI-IDSSKFIAKIR---PDMDGPLICEAKNYLGSTKETVQLNVLRDP-----------------------LIHIDSNYRVPKNSNYSINCRVTSNPPPEFIKWYKLSN--MTDSSAVLISDDAKLNFILIDRSSTGMYACVTQNIQISTTGKRKPANSEKTMFLTVTYKPKEPQILGNKIISIMKGEKFIIKCSTDRKSPGEPFPTLKWIDVE---TKDIVSDMETFQVINSESRHNGKYKCLAENEIGKSFSRETALVTVNEAPSIITQHKNRKVFLSYSDLPQSISFTCEFRGQPLYEARWRYGNEKIPPSSQDFKIEDHRNISNERISQIFTKLTIDLYSRTFSQQTSLRSSPNGRYNCEADNRHGIASLDYFLXXXXXXXXXXNIRHRKIAASLNQNVVMIRCQAESISTMHIKWYKTNEHIVLPFQSKKYSIFEAEVTKYEPERDLFTPGLKVNELTIKDLENDDFSNYSCVASNDQGIKKVNFEVVFKSQP 2306 K + PD +I +E +L I +++G Y C + + + +A ++V P I +N+ ++ + +QC ++ GIPPP+I ++ ++ + N +++ +L +E++G C A N G +++T+L+ + VP + Q + LSC V P +I W+ + +G I I+ + ++R P +G C A + G++ + + +++ P + ++S + V ++I C V+ PPP I WY +S ++ D L D+S +G+Y C N + G N +KT + P G +++ + F I C G+P P + W+ + T+ +V++ + + N H G + C A+N G T +TV+ P+I +++ K+ L D I C + P W Y EKI D ++ H TI Q L ++ G + C+ N G SL Y L + P I + + + + I C+A + + W K I L KK+S+ + L I + + +D NY+CV +N+ G ++ V + P Sbjct: 741 KDLIKPDDYIKI---NEGQLHIMGAKDEDAGAYSCVGENMAGKD--VQVANLSVGRVPTIIESPHTVRVNIERQ---VTLQC-LAVGIPPPEIEW--------QKGNVLLATLNNPRYTQLADGNLLITDAQIEDQGQFTCIARNTYGQQSQSTTLMVTGLVSPVLGHVPPEEQLIEGQDLTLSCVVVLGTPKPSIVWIKDDKPVEEGPTIKIEGGGSLLRLRGGNPKDEGKYTCIAVSPAGNSTLHINVQLIKKPEFVYKPEGGIVFKPTISGMDEKHVAVVNSTHDVLDGEGFAIPCVVSGTPPP-IITWYLDGRPITPNSRDFTVTADNTLIVRKADKSYSGVYTCQATN----SAGD----NEQKTTIRIMNTPMISP---GQSSFNMVVDDLFTIPCDVY----GDPKPVITWLLDDKPFTEGVVNEDGSLTIPNVNEAHRGTFTCHAQNAAGND--TRTVTLTVHTTPTINAENQ-EKIALQNDD----IVLECPAKALPPPVRLWTYEGEKI-----DSQLIPH---------------TIREDGALVLQNVKLENT--GVFVCQVSNLAGEDSLSYTLTVHEKPKIISEVP--GVVDVVKGFTIEIPCRATGVPEVIRTWNKNG--IDLKMDEKKFSVD------------------NLGTLRIYEADKNDIGNYNCVVTNEAGTSQMTTHVDVQEPP 1362 HSP 3 Score: 85.5001 bits (210), Expect = 2.670e-16 Identity = 152/735 (20.68%), Postives = 273/735 (37.14%), Query Frame = 3 Query: 165 NATVNSKENLTLECVVDQQNIVYSWEYKPFHIKSNIMSKVLGFCYFEKPCVVPDSESQITISHESRLTIHNISSDNSGYYVC-RVTLLTTSEHIISLAVVTVKTPPKSISFHFNKSINVFQEQEFIAIQCSVSGGIPPPKISMYIVKDNAIKRLKIISSNFPNSTIAEVSAISLWRPHYLENR-GFVMCTAINDAGVLTKNTSLLNIKYKPKIKPFVPNTVNAMINQTIDLSCEVYANPAATIQWVIMQGLQIIDSSKFIAKI-----RPDM---DGPLICEAKNYLGSTKETVQLNVLRDPLIHIDSNYRVPKNSN-YSINCRVTSNPPPEFIKWYKLSNMTDSSAVLISDDAKLNFILIDRSST----GMYACVTQNIQISTTGKRKPANSEKTMFLTVTYKPKEPQILGNKIISIMKGEKFIIKCSTDRKSPGEPFPTLKWI------DVETKDIVSDMETFQVINSESRHNGKYKCLAENEIGKS--------FSRETALVTVNEAPSIITQHKNRKVFLSYSDLPQSISFTCEFRGQPLYEARWRYGNEKIPPSSQDFKIEDHRNISNERISQIFTKLTIDLYSRTFSQQTSLRSSPNGRYNCEADNRHGIASLDYFLXXXXXXXXXXNIRHRKIAASLNQNVVMIRCQAESISTMHIKWYKTNEHIVLPFQSKKYSIFEAEVTKYEPERDLFTPGLKVNELTIKDLENDDFSNYSCVASNDQGIKKVNF 2282 N V + + LTLEC ++ + V+ + F + D +Q + S +S+L I + +++ Y C V +E + VTV TPPK F S + I C G IPPP+IS ++ ++ P T + +SL + N+ G C A N AG ++T + I P++ + + + + CEV+ NP + W+ D +F K+ R G C A N G ++ T + VL P I + K N Y ++C+VT P P ++ W + + + N +L R++T G Y+C+ N + A+ +F T++ E +I++GE I+C D G P PT+ W+ +++ + +T ++ ++ G Y C+A N G S +++ T+++ P + + I C G P W+ G++ +P S+ H ++N DL + S+ + G+Y+C A N G + Y + P + + + + + + C S I W++ ++ + L +YSI P+ + +TI + D Y C ASN+ G ++ Sbjct: 2951 NVEVQAGDPLTLECPIEDTSGVHITWSRQFGKDGQL-----------------DMRAQSS-SDKSKLYIMQATPEDADSYSCIAVNDAGGAEAVFQ---VTVNTPPKIFGDSF--STTEIVADTTLEIPCRTEG-IPPPEISWFLDGKPILE--------MPGVTYKQ-GDLSLRIDNIKPNQEGRYTCVAENKAGRAEQDT-YVEISEPPRVV-MASEVMRVVEGRQTTIRCEVFGNPEPVVNWLKDGEPYTSDLLQFSTKLSYLHLRETTLADGGTYTCIATNKAGESQTTTDVEVLVPPRIEDEERVLQGKEGNTYMVHCQVTGRPVP-YVTWKRNGKEIE----------QFNPVLHIRNATRADEGKYSCIASNEAGTAV-----ADFLIDVFTKPTFETHE------TTFNIVEGESAKIECKID----GHPKPTISWLKGGRPFNMDNIILSPRGDTLMILKAQRFDGGLYTCVATNSYGDSEQDFKVNVYTKPYIDETIDQTPKAVAGGE--------------IILKCPVLGNPTPTVTWKRGDDAVPNDSR------HTIVNN-----------YDL------KINSVTTEDAGQYSCIAVNEAGNLTTHYAAEVIGKPTFVR--KGGNLYEVIENDTITMDCGVTSRPLPSISWFRGDKPVYL---YDRYSI--------SPDG---------SHITINKAKLSDGGKYICRASNEAGTSDIDL 3565 HSP 4 Score: 84.3445 bits (207), Expect = 5.239e-16 Identity = 159/677 (23.49%), Postives = 256/677 (37.81%), Query Frame = 3 Query: 363 LTIHNISSDNSGYYVCRVTLLTTSEHIISLA--VVTVKTPPKSISFHFNKSINVFQEQEFIAIQCSVSGGIPPPKISMYIVKDNAIKRLKIISSNFPNSTIAEVSAISLWRPHYLENRGFVMCTAINDAGVLTKNTSLLNIKYKPKIKPFVPNTVNAMINQTIDLSCEVYANPAATIQWVIMQGLQIIDSSKFIA--------KIRPDMDGPLICEAKNYLGSTKETVQLNVLRDP-LIHIDSN-YRVPKNSNYSINCRVTSNPPPEFIKWY----------KLSNMTDSSAVLISDDAKLNFILIDRSSTGMYACVTQNIQISTTGKRKPANSEKTMFLTVTYKPK--EPQILGNKIISIMKGEKFIIKCSTDRKSPGEPFPTLKW----IDVETKD----IVSDMETFQVINSESRHNGKYKCLAENEIGKSFSRETALVTVNEAPSIITQHKNRKVFLSYSDLPQSISFTCEFR-----GQPLYEARWRYGNEKIPPSSQDFKIEDHRNISNERISQIFTKLTIDLYSRTFSQQTSLRSSPNGRYNCEADNRHGIASLDYFLXXXXXXXXXXNIRHRKIAASLNQNVVMIRCQAESISTMHIKWYKTNEHIVLPFQSKKYSIFEAEVTKYEPERDLFTPGLKVNELTIKDLENDDFSNYSCVASNDQGIKKVNF 2282 L I N + + G Y C + ++E ++A ++ V T P +F +++ E E I+C + G P P IS ++ II S ++ + + + + G C A N G ++ + N+ KP I + T A+ I L C V NP T+ W DS I + + G C A N G+ V+ P + N Y V +N +++C VTS P P I W+ + S D S + I + AKL S G Y C N + S+ + L + PK + I+GN + + + ++C G P P + W +D+ D + + ETF + N + G+Y C A N GK+ S + +L + +P H + D +I+ TC + + + W ++D + D N IS KLTI Q SL ++ G Y C A NR G ASL++ + I PP+I + + ++NQ +M RC IKW K + + + I E + L I ++D +SCVA ND G+K++ Sbjct: 3264 LHIRNATRADEGKYSC----IASNEAGTAVADFLIDVFTKP---TFETHETTFNIVEGESAKIECKIDGH-PKPTIS-WLKGGRPFNMDNIILSPRGDT-------LMILKAQRFDG-GLYTCVATNSYGDSEQDFKV-NVYTKPYIDETIDQTPKAVAGGEIILKCPVLGNPTPTVTWKRGDDAVPNDSRHTIVNNYDLKINSVTTEDAGQYSCIAVNEAGNLTTHYAAEVIGKPTFVRKGGNLYEVIENDTITMDCGVTSRPLPS-ISWFRGDKPVYLYDRYSISPDGSHITI-NKAKL-------SDGGKYICRASN---------EAGTSDIDLILKILVPPKIDKSNIIGNPLAIVAR--TIYLECPIS----GIPQPDVIWTKNGMDINMTDSRVILAQNNETFGIENVQVTDQGRYTCTATNRGGKA-SHDFSLDVL--SPPEFDIHGTQPTIKREGD---TITLTCPIKLAEDIADQVMDVSW----------TKDSRALDGDLTDNVDISDDGRKLTI--------SQASLENA--GLYTCIALNRAGEASLEFKVEILSPPVIDISRNDVQPQVAVNQPTIM-RCAVTGHPFPSIKWLKNGKEVT---DDENIRIVE-----------------QGQVLQILRTDSDHAGKWSCVAENDAGVKELEM 3851 HSP 5 Score: 83.9593 bits (206), Expect = 8.256e-16 Identity = 145/704 (20.60%), Postives = 267/704 (37.93%), Query Frame = 3 Query: 291 FCYFEKPCVVPDSESQITISHESRLTIHNISSDNSGYYVCRVTLLTTSEHIISLA----VVTVKTPPKSISFHFNKSIN--VFQEQEFIAIQCSVSGGIPPPKISMYIVKDNAIKRLKIISSNFPNSTIAEVSAISLWRPHYLENRGFVMCTAINDAGVLTKNTSLLNIKY-----KPKIKPFVPNTVNAMINQTIDLSCEVYANPAATIQWVI-------MQGLQIIDSSKFIAKIRPDMDGPLICEAKNYLGSTKETVQLNVLRDPLIHID-SNYRVPKNSNYSINCRV--TSNPPPEFIKWYKLSNMTDSSAVLISDDAKLNFILIDRSSTGMYACVTQNIQISTTGKRKPANSEKTMFLTVTYKPKEPQILGNKI--ISIMKGEKFIIKCSTDRKSPGEPFPTLKWIDVETKDIV---------SDMETFQVINSESRHNGKYKCLAENEIGKSFSRETALVTVNEAPSIITQHKNRKVFLSYSDLPQSISFTCEFRGQPLYEARWRYGNEKIPPSSQDFKIEDHRNISNERISQIFTKLTIDLYSRTFSQQTSLRSSPNGRYNCEADNRHGIASLDYFLXXXXXXXXXXNIRHRKIAASLNQNVVMIRCQAESISTMHIKWYKTNEHIVLPFQSKKYSIFEAEVTKYEPERDLFTPGLKVNELTIKDLENDDFSNYSCVASNDQGIKKVNFEVVFKSQP 2306 + F+ + PDS + ++ L I +++G Y C +++ + A +V V PP HF K V + + + + C+ +P + + D +++ I S N V+ I L ++ GF CTA+N+AG+ K L+ I+ + K+ P + + + + L C P TI ++ + II S+ I + +++G C A+N G +++ + + VL P + + N V ++ C + TS + + + D A SD +KL + Y+C+ N A + +F P P+I G+ I+ I C T+ G P P + W ++ K I+ D+ + ++ N + G+Y C+AEN+ G++ + V ++E P ++ + +V + + CE G P W E P + D + Q TKL+ L+ R +T+L + G Y C A N+ G + + + PP I+ ++ N M+ CQ ++ W + + I + F P L I++ D YSC+ASN+ G +F + ++P Sbjct: 2701 YWLFDDKPLEPDSAAYELTNNGETLKIVRSQVEHAGTYTCE------AQNNVGKARKDFLVRVTAPP-----HFEKEREEVVARVGDTMLLTCNAESSVPLSSVYWH-AHDESVQNGVITSKYAANEKTLNVTNIQL------DDEGFYYCTAVNEAGITKKFFKLIVIETPYFLDQQKLYPII-------LGKRLTLDCSATGTPPPTILFMKDGKRLNESDEVDIIGSTLVIDNPQKEVEGRYTCIAENKAGRSEKDMMVEVLLPPKLSKEWINVEVQAGDPLTLECPIEDTSGVHITWSRQFGKDGQLDMRAQSSSDKSKLYIMQATPEDADSYSCIAVN----------DAGGAEAVFQVTVNTP--PKIFGDSFSTTEIVADTTLEIPCRTE----GIPPPEISWF-LDGKPILEMPGVTYKQGDL-SLRIDNIKPNQEGRYTCVAENKAGRA--EQDTYVEISEPPRVVMASEVMRVVEG-----RQTTIRCEVFGNPEPVVNWLKDGE---PYTSD-------------LLQFSTKLSY-LHLR----ETTL--ADGGTYTCIATNKAGESQTTTDVEVLVPPRIED---EERVLQGKEGNTYMVHCQVTGRPVPYVTWKRNGKEI-----------------------EQFNPVLH-----IRNATRADEGKYSCIASNEAGTAVADFLIDVFTKP 3300 HSP 6 Score: 80.1073 bits (196), Expect = 1.182e-14 Identity = 122/562 (21.71%), Postives = 225/562 (40.04%), Query Frame = 3 Query: 342 TISHESRLTIHNISSDNSGYYVCRVTLLTTSEHIISLAVVTVKTPPKSISFHFNKSINVFQEQEFIAIQCSVSGGIPPPKISMYIVKDNAIKRLKIISSNFPNSTIAEVSAISLWRPHYLENRGFVMCTAINDAGVLTKNTSLLNIKYKPKIKPFVPNTVNAMINQTIDLSCEVYANPAATIQWVIMQGLQI-IDSSKFIAKIRPDMDGPLI-------------CEAKNYLGSTKETVQLNVLRDPLIH---IDSNYRVPKNSNYSINCRVTSNPPPEFIKWYKLSN--MTDSSAVLISDDA-KLNFILIDRSSTGMYACVTQNIQISTTGKRKPANSEKTMFLTVTYKPKEPQILGNKIISIMKGEKFIIKCSTDRKSPGEPFPTLKWI----------DVETKDIVSDMETFQVINSESRHNGKYKCLAENEIGKSFSRETALVTVNEAPSIITQHKNRKVFLSYSDLPQSISFTCEFRGQPLYEARWRY---GNEKIPPSSQDFKIEDHRNISNERISQIFTKLTIDLYSRTFSQQTSLRSSPNGRYNCEADNRHGIA 1928 TI + L + N+ +N+G +VC+V+ L + + +TV PK IS ++V + I I C +G P I + N I LK+ F ++ + + ++ + G C N+AG ++ T+ ++++ P I P A++ ++L C V A+P A++ W +G+ I D+ ++ + DG L+ C+A N G + +Q+ V+ P I + + + ++ +S+ C V SNP P+ I WY + D ++ SDD KL+ + +G+Y CV +N K+ + V + K + +GE+ + C G P P + W+ + + +D T + + G Y C+A+++ G + L + A I+ + N +VFL + IS +C+ + + + + + G+E P + + HR LY T + NG+Y C N G A Sbjct: 1227 TIREDGALVLQNVKLENTGVFVCQVSNLAGEDSL--SYTLTVHEKPKIIS-EVPGVVDVVKGFT-IEIPCRATG--VPEVIRTW--NKNGID-LKMDEKKF---SVDNLGTLRIYEADK-NDIGNYNCVVTNEAGT-SQMTTHVDVQEPPIILPSTQTNNTAVVGDRVELKCYVEASPPASVTW-FRRGIAIGTDTKGYVV----ESDGTLVIQSASVEDATIYTCKASNPAGKAEANLQVTVIASPDIKDPDVVTQESIKESHPFSLYCPVFSNPLPQ-ISWYLNDKPLIDDKTSWKTSDDKRKLHVFKAKITDSGVYKCVARNAA---------GEGSKSFQVEVIVPLNLDESKYKKKVFAKEGEEVTLGCPVS----GFPVPQINWVVDGTVVEPGKKYKGATLSNDGLTLHFDSVSVKQEGNYHCVAQSK-GNILDIDVELSVL--AVPIVGEDDNLEVFLG-----KDISLSCDLQTESDDKTTFVWSINGSESDRPDNVQIPSDGHR-----------------LYI------TDAKPENNGKYMCRVTNSAGKA 1724 HSP 7 Score: 78.5666 bits (192), Expect = 3.274e-14 Identity = 130/565 (23.01%), Postives = 214/565 (37.88%), Query Frame = 3 Query: 330 ESQITISHESRLTIHNISSDNSGYYVCRVTLLTTSEHIISLAVVTVKTPPKSISFHFNKSINVFQ--EQEFIAIQCSVSGGIPPPKISMYIVKDNAIKRLKIISSNFPNSTIAEVSAISLWRPHYLENRGFVMCTAINDAGVLTKNTSL-LNIKYKPKI-KPFVPNTVNAMINQTIDLSCEVYANPAATIQWVIMQGLQI--IDSSKFIAK---------IRPDMDGPLICEAKNYLGSTKETVQLNVLRDPLIHIDSNYRVPKNSNYSINCRVTSNPPPEF------IKWYKLSNMTDSSA---VLISDDA-KLNFILIDRSSTGMYACVTQNIQISTTGKRKPANSEKTMFLTVTYKPKEPQILGNKIISIMKGEKFIIKCSTDRKSPGEPFPTLKWI-------DVETKDIVSDMETFQVINSESRHNGKYKCLAENEIGKSFSRETALVTVNEAPSIITQHKNRKVFLSYSDLPQSISFTCEFRGQPLYEARWRYGNEKIPPSSQDFKIEDHRNISNERISQIFTKLTIDLYSRTFSQQTSLRSSPNGRYNCEADNRHGIA 1928 +S+ TI + L I++++++++G Y C + + A + P K N+++ E + I + C V+ P P IS + D + S + S I A L + G +C A N+AG T + L L I PKI K + A++ +TI L C + P + W G+ I DS +A+ ++ G C A N G L+VL P I K +I + + W K S D V ISDD KL + G+Y C+ N + + K + ++ +PQ+ N + I++C+ G PFP++KW+ D E IV + Q++ ++S H GK+ C+AEN+ G +E +V P +++ + + L ++I+ C G P + +W G I F D RIS +L I L+ + G Y C+A N G + Sbjct: 3434 DSRHTIVNNYDLKINSVTTEDAGQYSC-IAVNEAGNLTTHYAAEVIGKP-----TFVRKGGNLYEVIENDTITMDCGVTSR-PLPSIS-WFRGDKPVYLYDRYSISPDGSHITINKA-------KLSDGGKYICRASNEAG--TSDIDLILKILVPPKIDKSNIIGNPLAIVARTIYLECPISGIPQPDVIWT-KNGMDINMTDSRVILAQNNETFGIENVQVTDQGRYTCTATNRGGKASHDFSLDVLSPPEFDIHGTQPTIKREGDTITLTCPIKLAEDIADQVMDVSWTKDSRALDGDLTDNVDISDDGRKLTISQASLENAGLYTCIALNRAGEASLEFK-VEILSPPVIDISRNDVQPQVAVN--------QPTIMRCAVT----GHPFPSIKWLKNGKEVTDDENIRIVEQGQVLQILRTDSDHAGKWSCVAENDAG---VKELEMVLDVFTPPVVSVKSDNPI----KALGETITLFCNASGNPYPQLKWAKGGSLI------FDSPD-----GARISLKGARLDI----------PHLKKTDVGDYTCQALNAAGTS 3939 HSP 8 Score: 76.6406 bits (187), Expect = 1.197e-13 Identity = 148/650 (22.77%), Postives = 248/650 (38.15%), Query Frame = 3 Query: 516 VFQEQEFIAIQCSVSGG---IPPPKISMYIVKDNAI-----KRLKIISSNFPNSTIAEVSAISLWRPHYLENRGFVMCTAINDAGVLTKNTSLLNIKYKPKIKPFVPNTVNAMINQT--IDLSCEVYANPAATIQWVIMQGLQIIDSSKFIAKIRPDMD--------GPLICEAKNYLGSTKETVQLNVLRDPLIH---IDSNYRVPKNSNYSINCRVTSNPPPEFIKWYKLSNMTDSSAVLISDDAKLNFILIDRSST---GMYACVTQNIQISTTGKRKPANSEKTMFLTVTYKPKEPQILGNKIISIMKGEKFIIKCSTDRKSPGEPFPTLKWI-------DVETKDIVSDMETFQVINSESRHNGKYKCLAENEIGKS-FSRETALVTVNEAPSIITQHKNRKVFLSYSDLPQSISFTC------EFRGQPLYEARWRYGNEKIPPSSQDFKIEDHR--NISNERISQIFTKLTIDLYSRTFSQQTSLRSSPNGRYNCEADNRHGIASLDYFLXXXXXXXXXXNIRHRKIAASLNQNVVMIRCQAESISTMHIKWYKTNEHIVLPFQSKKYSIFEAEVTKYEPERDLFTPG-LKVNELTIKDLENDDFSNYSCVASNDQGIKKVNFEVVFKSQPDPPYDLRVTDFE 2342 +F+E E I + C VS G I K + + +++AI RL I+++N R H C A N AG ++K+ ++ ++ PKIK V V IN+ I L+C+ NP T +W QG + + F+ + G C A N +G +T+ ++V P +S V + ++ C V + I W + + A F+ I + T G YAC N + + KT L V P G ++++ ++ C G+P P + W D+++ ++S+ + F+++++E H G Y C+A+N++G + S + ++T P I KN + LP F C F+GQ + W + I D + ED R +SN+R +LTI ++ + G+Y+C N G S D F P + K ++ + V + C A I W+K E I + E D+ G L N+L I ++ D Y+C A N G + + V + P D +D+E Sbjct: 1837 IFRESETITLDCPVSLGDFQITWMKQGLPLTENDAIFTLDNTRLTILNAN---------------RDH----EDIYTCVANNTAGQVSKDFDVV-VQVLPKIKNAV---VTLEINEGEEIILTCDAEGNPTPTAKWDFNQG-DLPKEAVFVNNNHTVVVNNVTKYHTGVYKCYATNKVGQAVKTINVHVRTKPRFESGLTESELTVNLTRSITLECDV-DDAIGVGISWTVNGKPFLAETDGVQTLAGGRFLHIVSAKTDDHGSYACTVTN---------EAGVATKTFNLFVQVPPTIVNEGGE--YTVIENNSLVLPCEVT----GKPNPVVTWTKDGRPVGDLKSVQVLSEGQQFKIVHAEIAHKGSYICMAKNDVGTAEISFDVDIIT---RPMIQKGIKNIVTAIKGGALP----FKCPIDDDKNFKGQII----WLRNYQPI-----DLEAEDARITRLSNDR------RLTI----------LNVTENDEGQYSCRVKNDAGENSFD-FKATVLVPPTIIMLDKDKNKTAVEHSTVTLSCPATGKPEPDITWFKDGEAIHI-----------------ENIADIIPNGELNGNQLKITRIKEGDAGKYTCEADNSAGSVEQDVNVNVITIPKIEKDGIPSDYE 2396 HSP 9 Score: 72.0182 bits (175), Expect = 3.684e-12 Identity = 137/614 (22.31%), Postives = 240/614 (39.09%), Query Frame = 3 Query: 318 VPDSESQITISHESRLTIHNISSDNSGYYVCRVTLLTTSEHIISLAVVTVKTPPKSISFHFNKSINVFQEQEFIAIQCSVSGGIPPPKISMYIVKDNAIKRLKIISSNFPNSTIAEVSAISLWRPHYLE-NRGFVMCTAINDAGVLTKNTSLLNIKYKPKI-KPFVPNTVNAMINQTIDLSCEVYANPAATIQWVI--------MQGLQIIDSSKFIA--KIRPDMDGPLICEAKNYLGSTKETVQLNVLRDPLIHIDSNYRVPKNSNYSINCRVTSNPPPEFIKWYKLSNMTDSS--AVLISDDAKLNFILIDRS-STGMYACVTQNIQISTTGKRKPANSEKTMFLTVTYKPKEPQILGN--KIISIMKGEKFIIKCSTDRKSPGEPFPTLKWI-------DVETKDIVSDMETFQVINSESRHNGKYKCLAENEIGKSFSRETALVTVNEAPSIITQHKNRKVFLSYSDLPQSISFTCEFRGQPLYEARWRYGNEKIPPSSQDFKIEDHRNISNERISQIFTKLTIDLYSRTFSQQTSLRSSPNGRYNCEADNRHGIASLDYFLXXXXXXXXXXNIRHRKIAASLNQNVVMIRCQAESISTMHIKWYKTNE 2087 V D E+ + L I SD++G + C + + L +V P +S + I E I + C+ SG P P++ K ++ I S P+ + L PH + + G C A+N AG + S+ ++ P+I + + + Q++ L C P ++W + G+ + S FI + G C A+N GS ++V++ P+I +V + I C V P P+ + W + N ++ V D ++ I+ RS +G+Y C S T + A T+ + V+ P+I+ + +++ G KF + C+ G P P + W D E + T + +E RH Y+C A+N+ G + E + T+ AP I T NR +++ S+ +++ CE + + + G +P ++ F ED++ I + S R S G Y+C A N+ G A+ L + P I R + + + V + C+A + I WYK NE Sbjct: 3808 VTDDENIRIVEQGQVLQILRTDSDHAGKWSC---VAENDAGVKELEMVLDVFTPPVVSVKSDNPIKALGET--ITLFCNASGN-PYPQLKW--AKGGSL----IFDS--PDGARISLKGARLDIPHLKKTDVGDYTCQALNAAGTSEASVSV-DVLVPPEINRDGIDMSPRLPAQQSLTLQCLAQGKPVPQMRWTLNGTALTHSTPGITVASDSTFIQINNVSLSDKGVYTCYAENVAGSDNLMYNVDVVQAPVISNGGTKQVIEGELAVIECLVEGYPAPQ-VSWLRNGNRVETGVQGVRYVTDGRMLTIIEARSLDSGIYLC-------SATNEAGSAQQAYTLEVLVS-----PKIITSTPGVLTPSSGSKFSLPCAVR----GYPDPIISWTLNGNDIKDGENGHTIGADGTLHIEKAEERHL-IYECTAKNDAGAD-TLEFPVQTI-VAPKISTS-GNR--YINGSEGTETV-IKCEIESESSEFSWSKNGVPLLPSNNLIFS-EDYKLI----------------------KILSTRLSDQGEYSCTAANKAGNATQKTNLNVGVAPKIMERPRTQVVHKG---DQVTLWCEASGVPQPAITWYKDNE 4356 HSP 10 Score: 70.4774 bits (171), Expect = 1.110e-11 Identity = 144/689 (20.90%), Postives = 249/689 (36.14%), Query Frame = 3 Query: 330 ESQITISHESRLTIHNISSDNSGYYVCRVTLLTTSEHIISLAVVTVKTPPKSISFHFNKSINVFQEQEFIAIQCSVSGGIPPPKISMYIVKDNAIKRLKIISSNFPNSTIAEVSAISLWRPHYLENRGFVMCTAINDAGVLTKNTSLLNIKYKPKIK-PFVPNTVNAMINQTIDLSCEVYANPAATIQWVIMQGLQIIDSSKF----------IAKIRPDMDGPLICEAKNYLGSTKETVQLNVLRDPLIHIDSNYR----VPKNSNYSINCRVTSNPPPEFIKWYKLSNMTD-----SSAVLISDDAKLNFILIDRSSTGMYACVTQNIQISTTGKRKPANSEKTMFLTVTYKPKEPQILGNKIISIMKGEKFIIKCSTDRKSPGEPFPTLKW-IDVETKD------IVSDMETFQVINSESRHNGKYKCLAENEIGKSFSRETALVTVNEAPSIITQ--HKNRKVFLSYSDLPQSISFTCEFRGQPLYEARWRYGNEKIPPSSQDFKIEDHRNISNERISQI-FTKLTIDLYSRTFSQQTSLRSSPNGRYNCEADNRHGIASLDYFLXXXXXXXXXXNIRHRKIAASLNQNVVMIRCQAESISTMHIKWYKTNEHIVLPFQSKKYSIFEAEVTKYEPERDLFTPGLKVNELTIKDLENDDFSNYSCVASNDQGIKKVNFEVVFKSQP 2306 E + ++ + L I+ ++ G Y C VT + + + V V+ PP I ++ N + + ++C V PP ++ + R I + E + + +E+ C A N AG N + I P IK P V + + L C V++NP I W + I D + + + K + G C A+N G ++ Q+ V+ PL +S Y+ + ++ C V+ P P+ I W + + A L +D L+F + G Y CV Q + G + E ++ P + + + + G+ + C D ++ + T W I+ D I SD + +++ +NGKY C N GK+ T + V E P + N+K+ + I C+ G P W+ + D + +E +S + KLT + + +C A+N+ G AS D+F+ P K I + + C S+ I W K LP ++ +IF + T+ LTI + D Y+CVA+N G +F+VV + P Sbjct: 1315 EKKFSVDNLGTLRIYEADKNDIGNYNCVVTNEAGTSQMTTH--VDVQEPP--IILPSTQTNNTAVVGDRVELKCYVEAS-PPASVTWF--------RRGIAIGTDTKGYVVESDGTLVIQSASVEDATIYTCKASNPAGKAEANLQVTVIA-SPDIKDPDVVTQESIKESHPFSLYCPVFSNPLPQISWYLNDKPLIDDKTSWKTSDDKRKLHVFKAKITDSGVYKCVARNAAGEGSKSFQVEVIV-PLNLDESKYKKKVFAKEGEEVTLGCPVSGFPVPQ-INWVVDGTVVEPGKKYKGATLSNDGLTLHFDSVSVKQEGNYHCVAQ-----SKGNILDIDVELSVLAV-------PIVGEDDNLEVFLGKDISLSC--DLQTESDDKTTFVWSINGSESDRPDNVQIPSDGHRLYITDAKPENNGKYMCRVTNSAGKA--ERTLTLDVLEPPVFVEPVFEANQKLIGN-----NPIILQCQVTGNPKPTVIWKIDGNDV----------DKSWLFDESLSLLRIEKLT----------------GKSAQISCTAENKAGTASRDFFIQNIAAPTFKNEGDQETIFRE--SETITLDCPV-SLGDFQITWMKQG----LPL-TENDAIFTLDNTR----------------LTILNANRDHEDIYTCVANNTAGQVSKDFDVVVQVLP 1916 HSP 11 Score: 67.3958 bits (163), Expect = 7.887e-11 Identity = 115/559 (20.57%), Postives = 209/559 (37.39%), Query Frame = 3 Query: 702 ENRGFVMCTAINDAGVLTKNTSLLNIKYKPKIKPFVPNTVNAMINQTIDLSCEVYANPAATIQWVI----MQGLQIIDSSKFIAKIRP--DMDGPLICEAKNYLGSTKETVQLNVLRDPLIHIDSNYRV--PKNSNYSINCRVTSNPPPEF-IKWYKLS-NMTDSSAVLISDDAKLNFILIDRSSTGMYACVTQNIQISTTGKRKPANSEKTMFLTVTYKPKEPQILGNKIIS--IMKGEKFIIKCSTDRKSPGEPFPTLKWIDVETKDIVSDM------ETFQVINSESRHNGKYKCLAENEIGKSFSRETALVTVNEAPSIITQHKNRKVFLSYSDLPQSISFTCEFRGQPLYEARWRYGNEKIPPSSQDFKIEDHRNISNERISQIFTKLTIDLYSRTFSQQTSLRSSPNGRYNCEADNRHGIASLDYFLXXXXXXXXXXNIRHRKIAASLNQNVVMIRCQAESISTMHIKWYKTN------EHIVLPFQSKKYSIFEAEVTKYEPERDLFTPGLKVNELTIKDLENDDFSNYSCVASNDQGIKKVNFEVVFKSQP 2306 EN G MC N AG + +L ++ ++P + N I L C+V NP T+ W I + + D S + +I + C A+N G+ + + P + + ++ +++C V+ +F I W K +T++ A+ D+ +L + +R +Y CV N T G+ K + V PK + N +++ I +GE+ I+ C + G P PT KW D D+ + T V N H G YKC A N++G++ +T V V P + ++ + +L +SI+ C+ W + + F E T L F S ++ +G Y C N G+A+ + L ++ PP I + + N +++ C+ + W K + + + + +++ I AE+ +Y C+A ND G +++F+V ++P Sbjct: 1708 ENNGKYMCRVTNSAGKAERTLTLDVLEPPVFVEPVFEANQKLIGNNPIILQCQVTGNPKPTVIWKIDGNDVDKSWLFDESLSLLRIEKLTGKSAQISCTAENKAGTASRDFFIQNIAAPTFKNEGDQETIFRESETITLDCPVSLG---DFQITWMKQGLPLTENDAIFTLDNTRLTILNANRDHEDIYTCVANN----TAGQ-----VSKDFDVVVQVLPK----IKNAVVTLEINEGEEIILTCDAE----GNPTPTAKW-DFNQGDLPKEAVFVNNNHTVVVNNVTKYHTGVYKCYATNKVGQAV--KTINVHVRTKPRFESGLTESELTV---NLTRSITLECDVDDAIGVGISWTV-------NGKPFLAE--------------TDGVQTLAGGRFLHIVSAKTDDHGSYACTVTNEAGVATKTFNLFVQVPPTIVNEGGEYTV---IENNSLVLPCEVTGKPNPVVTWTKDGRPVGDLKSVQVLSEGQQFKIVHAEIAHK--------------------------GSYICMAKNDVGTAEISFDVDIITRP 2190 HSP 12 Score: 63.929 bits (154), Expect = 1.081e-9 Identity = 127/631 (20.13%), Postives = 239/631 (37.88%), Query Frame = 3 Query: 525 EQEFIAIQCSVSGGIPPPKISMYIVKDNAIKRLKIISSNFPNSTIAEVSAISLWRPHYLENRGFVMCTAINDAGVLTKNTSLLNIK-----YKPKIKPFVPNTVNAM-------INQTID--------LSCEVYANPAATIQWVIMQGLQII----------DSSKFIAKIRPDMDGPLICEAKNYLGSTKETVQLNVLRDPLIH-IDSNYRVPKNSNYSINCRVTSNPPPEFIKWYKLSNMTDSSAVLISDDAKLNFILIDRSSTGMYACVTQNIQISTTGKRKPANSEKTMFLTVTYKPKEPQILGNKIISIMKGEKFIIKCSTDRKSPGEPFPTLKWIDVETKDI---VSDMETFQVINSESRHNGKYKCLAENEIGKSFSRETALVTVNEAPSIITQHKNR-KVFLSYSDLPQSISFTCEFRGQPLYEARWRYGNEKIPPSSQDFKIEDHR-NISNERISQIFTKLTIDLYSRTFSQQTSLRSSPNGRYNCEADNRHGIASLDYFLXXXXXXXXXXNIRHRKIAASLNQNVVMIRCQAESISTMHIKWYKTNEHIVLPFQSKKYSIFEAEVTKYEPERDLFTPGLKVNELTIKDLENDDFSNYSCVASNDQGIKKVNFEVVFKSQPD 2309 E + + + C V G P P I ++I D ++ P I ++ R ++ G C A++ AG T + ++ IK YKP+ T++ M +N T D + C V P I W + G I D++ + K G C+A N G ++ + ++ P+I S++ + + ++I C V +P P I W L + + ++++D L ++ + G + C QN N +T+ LTV P KI ++ + +++C P T + ++++ I + + + N + + G + C N G+ T +TV+E P II++ V ++ I C G P W + D K+++ + ++ N +I+ D+ G YNC N G + + + ++ PPII + + A ++ V ++C E+ + W++ I + +K Y + E++ T L I+ +D + Y+C ASN G + N +V + PD Sbjct: 900 EGQDLTLSCVVVLGTPKPSI-VWIKDDKPVEE-------GPTIKIEGGGSLLRLRGGNPKDEGKYTCIAVSPAGNSTLHINVQLIKKPEFVYKPEGGIVFKPTISGMDEKHVAVVNSTHDVLDGEGFAIPCVVSGTPPPIITWY-LDGRPITPNSRDFTVTADNTLIVRKADKSYSGVYTCQATNSAGDNEQKTTIRIMNTPMISPGQSSFNMVVDDLFTIPCDVYGDPKP-VITW--LLDDKPFTEGVVNEDGSLTIPNVNEAHRGTFTCHAQNAA---------GNDTRTVTLTVHTTPTINAENQEKIA--LQNDDIVLECPAKALPPPVRLWTYEGEKIDSQLIPHTIREDGALVLQNVKLENTGVFVCQVSNLAGEDSLSYT--LTVHEKPKIISEVPGVVDVVKGFT-----IEIPCRATGVPEVIRTWNK-------NGIDLKMDEKKFSVDNLGTLRIYEADKNDI----------------GNYNCVVTNEAGTSQMTTHVDVQEPPIILPSTQTNNTAVVGDR--VELKCYVEASPPASVTWFRRG--IAIGTDTKGY-VVESDGT-----------------LVIQSASVEDATIYTCKASNPAGKAEANLQVTVIASPD 1455 HSP 13 Score: 61.6178 bits (148), Expect = 5.083e-9 Identity = 132/640 (20.62%), Postives = 233/640 (36.41%), Query Frame = 3 Query: 153 ITPNNATVNSKENLTLECVVDQQ-NIVYSWEY--KPFHIKSNIMSKVLGFCYFEKPCVVPDSESQITISHESRLTIHNISSDNSGYYVCRVTLLTTSEHIISLAV--VTVKTPPKSISFHFNKSINVFQEQEFIAIQCSVSGGIPPPKISMYIVKDNAIKRLKIISSNFPNSTIAEVSAISLWRPHYLENRGFVMCTAINDAGVLTKNTSL-LNIKYKPKIKPFVPNTVNAMINQTIDLSCEVYANPAATIQWVIMQGLQIIDSSKFIAKI--------------RPDMDGPLICEAKNYLGSTKETVQLNVLRDPLIHI---DSNYRVPKNSNYSINCRVTSNPPPEFIKWYKLSNMTDSSAVLISDDA-----------KLNFILIDRSSTGMYACVTQNIQISTTGKRKPANSEKTMFLTVTYKPKEPQILGNKIISIMKGEKFIIKCSTDRKSP--------GEPFPTLKWIDVETKDIVSDMETFQVINSESRHNGKYKCLAENEIGKSFSRETALVTVNEAPSIITQHKNRKVFLSYSDLPQSISFTCEFRGQPLYEARWRYGNEKIPPSSQDFKIEDHRNISNERISQIFTKLTIDLYSRTFSQQTSLRSSPNGRYNCEADNRHGIASLDYFL 1946 +T + TVN ++TLEC VD + SW KPF +++ + + G + L I + +D+ G Y C V T+E ++ + V+ PP ++ ++ E + + C V+G P + + + LK + ++E + + ++G +C A ND G T S ++I +P I+ + N V A+ + C + + Q + ++ Q ID A+I + +G C KN G + VL P I + D N ++S +++C T P P+ I W+K D A+ I + A +L I G Y C N + E+ + + V PK + + E+ +I C + P G+P + K+ V+T + F++ ++S KY C+A NE G + V++ APS + R++ ++ + P ++ C +G P W I P+ + + R + Q + S GRY C A N G L+ L Sbjct: 2011 LTESELTVNLTRSITLECDVDDAIGVGISWTVNGKPFLAETDGVQTLAGGRF---------------------LHIVSAKTDDHGSYACTV----TNEAGVATKTFNLFVQVPPTIVNEGGEYTV---IENNSLVLPCEVTG--KPNPVVTWTKDGRPVGDLKSV------QVLSEGQQFKIVHAE-IAHKGSYICMAKNDVG--TAEISFDVDIITRPMIQKGIKNIVTAIKGGALPFKCPIDDDKNFKGQIIWLRNYQPIDLEAEDARITRLSNDRRLTILNVTENDEGQYSCRVKNDAGENSFDFKATVLVPPTIIMLDKDKNKTAVEHSTVTLSCPATGKPEPD-ITWFK-----DGEAIHIENIADIIPNGELNGNQLKITRIKEGDAGKYTCEADN---------SAGSVEQDVNVNVITIPKIEKDGIPSDYESQQNERVVISCPVYARPPAKITWLKAGKPLQSDKF--VKTSANGQKLYLFKLRETDSS---KYTCIATNEAGT--DKRDFKVSMLVAPSFDEPNIVRRITVNSGN-PSTLH--CPAKGSPSPTITWLKDGNAIEPNDRYVFFDAGRQL----------------------QISKTEGSDQGRYTCIATNSVGSDDLENTL 2564 HSP 14 Score: 55.4546 bits (132), Expect = 3.682e-7 Identity = 45/196 (22.96%), Postives = 78/196 (39.80%), Query Frame = 3 Query: 705 NRGFVMCTAINDAGVLTKNTSLLNIKYKPKIKPFVPNTVNAMINQTIDLSCEVYANPAATIQWVIMQ-------GLQIIDSSKF--IAKIRPDMDGPLICEAKNYLGSTKETVQLNVLRDPLIHIDSN-YRVPKNSNYSINCRVTSNPPPEFIKWYK-LSNMTDSSAVLISDDAKLNFILIDRSSTGMYACVTQNI 1259 + G C A N G+ T+ L +I P +K P V + + ++LSCE +P + W Q+ SKF I +G C A + G ++T L + P + I N V + S C+ P I+W+K ++ + ++ +L+ + G Y+CV +N+ Sbjct: 584 DAGVYECMARNAGGMSTRKMRL-DIMEPPSVK-VTPQDVYFNMREGVNLSCEAMGDPKPEVHWYFKGRHLLNDYKYQVGQDSKFLYIRDATHHDEGTYECRAMSQAGQARDTTDLMLATPPKVEIIQNKMMVGRGDRVSFECKTIRGKPHPKIRWFKNGKDLIKPDDYIKINEGQLHIMGAKDEDAGAYSCVGENM 777 HSP 15 Score: 54.6842 bits (130), Expect = 6.361e-7 Identity = 96/423 (22.70%), Postives = 164/423 (38.77%), Query Frame = 3 Query: 516 VFQEQEFIAIQCSVSGGIPPPKISMYIVKDNAIKRLKIISSNFPNSTIAEVSAISLWRPHYLENRGFVMCTAINDAGVLTKNTSLLNIKYKPKIKPFVPNTVNAMIN--QTIDLSCEVYANPAATIQWVIMQGL--------QIIDSSKFIAKIRPDMDGPLICEAKNYLGSTKETVQLNV----LRDPLIHIDSNYRV-PKNSNYSINCRVTSNPPPEFIKWYKLSNMTDSSAVLISDDAKLNFILIDRSSTGMYACVTQNIQISTTGKRKPANSEKTMFLTVTYKPKEPQ-ILGNKIISIMKGEKFIIKCSTDRKSPGEPFPTLKWID----VETKDIVSDMETFQVINSESRHNGKYKCLAENEIGKSFSRETALVTVNE----APSIITQHKNRKVFLSYS-DLPQSISFTCEFRGQPL 1709 V + + + + C SG +P P I+ Y KDN +++++ + T ++ G C A N ++ L+ + P++ VP +N N QT+ LSC P I W+ + QI+ ++ I + PD DG C AK+ G T +L V R I ++ + + PK + Y I+ T + P+ + W + +D+ LN + Y C+ G R S +T+ L PQ I+ K + G ++CS + G P PT+ W +E +V + + +G+Y C+A+N +G S +A + V+ P + KN V Y + S T E+ G P+ Sbjct: 4328 VVHKGDQVTLWCEASG-VPQPAITWY--KDN-----ELLTNTGVDETATTKKKSVIFSSISPSQAGVYTCKAENWVASTEEDIDLI-VMIPPEV---VPERMNVSTNPRQTVFLSCNATGIPEPVISWMRDSNIAIQNNEKYQILGTTLAIRNVLPDDDGFYHCIAKSDAGQKIATRKLIVNKPSDRPAPIWVECDEKGKPKKTEYMIDRGDTPDDNPQLLPWKDV------------EDSSLNGSI-------AYRCM--------PGPR----SSRTVLLHAA-----PQFIVKPKNTTAAIGAIVELRCS----AAGPPHPTITWAKDGKLIEDSKFEIAYSHLKVTLNSTSDSGEYTCMAQNSVGSSTV--SAFINVDNNILPTPKPSSNQKNVAVITCYERNQAYSRGLTWEYNGVPM 4696
BLAST of hemicentin-1 isoform X2 vs. Ensembl Celegans
Match: syg-2 (Synaptogenesis protein syg-2 [Source:UniProtKB/Swiss-Prot;Acc:Q9U3P2]) HSP 1 Score: 75.485 bits (184), Expect = 1.676e-13 Identity = 56/222 (25.23%), Postives = 107/222 (48.20%), Query Frame = 3 Query: 1884 NGRYNCEADNRHGI-ASLDYFLXXXXXXXXXXNIRHRKIAASLNQNVVMIRCQAESISTMHIKWYKTNEHIVLPFQSKKYSIFEAEVTKYEPERDLFTPGLKVNELTIKDLENDDFSN-YSCVASNDQGIKKVNFEVVFKSQPDPPYDLRVTDFEWDSVTINWKPGFNGGLTQNYEILVISENFGTQNVPFYSDKNENTLTITGLYPSTPYEIRIYAVNSIG 2543 +G Y C+ADN G+ A FL++ P + R+ K A L V RC+ ++ T+ W K + ++ S KYSI ++ E L+ IK++ DD++ C+A N G ++ ++ + PD P++L +T+ +++++ W+P F+GG Q +E+ +N ++ + L ++GL + Y +I ++N+ G Sbjct: 295 SGEYTCKADNGIGVPAEGQTFLLVNSAPRVLPVARYAKTAGILG-GVAKARCKVYAVPTVEFVWEKDEQ--LIKKNSSKYSIVNTQIDYSTYESTLW----------IKNIVPDDYTKKVKCIARNSFGTDHLSIPIIPPTHPDEPFNLTMTNSTLNTISVAWEPRFDGGSDQIFEVKYRRQN---DDLIHLVNTTHTNLRLSGLATANTYFFQIRSINARG 500
BLAST of hemicentin-1 isoform X2 vs. Ensembl Fly
Match: ed (gene:FBgn0000547 transcript:FBtr0334265) HSP 1 Score: 155.606 bits (392), Expect = 7.804e-38 Identity = 164/695 (23.60%), Postives = 296/695 (42.59%), Query Frame = 3 Query: 363 LTIHNISSD-NSGYYVCRVTLLTTSEHI-ISLAVVTVKTPPKSISFHFNKSINVFQEQEFIAIQCSVSGGIPPPKISMYIVKDNAIKRLKIISSNFPNS-TIAEVSAISLWRPHYLENRGFVMCTAINDAGVLTKNTSLLNIKYKPKIKPFVPNTVNAMINQTIDLSCEVYANP-AATIQWVIMQGLQIIDSS--KFIAKIRPDMDGPLICEAKNYLGSTKET-VQLNVLRDPLIHIDSNYR-VPKNSNYSINCRVTSNPPPEFIKWYKLSNMTDSSAVLISDDAKLNFILIDRSSTGMYACVTQNIQISTTGKRKPANSEKTMFLTVTYKPKEPQILGNKIISIMKGEKFIIKCSTDRKSPGEPFPTLKW---IDVE---TKDIVSDMETFQVINSESRHNGKYKCLAENEIGKSFSRETALVTVNEAPSIIT---QHKNRKVFLSYSDLPQSISFTCEFRGQPLYEARWRYGNEKIPPSSQDFKIEDHRNISNERISQIFTKLTIDLYSRTFSQQTSLRSSPNGRYNCEADNRHGIASLDYFLXXXXXXXXXXNIRHRKIAASLNQNVVMIRCQAESISTMHIKWYKTNEHIVLPFQSKKYSIFEAEVTKYEPERDLFTPGLKVNELTIKDLENDDFSNYSCVASNDQGIKKVNFEVVFKSQPDPPYDLRVTDFEWDSVTINWKPGFNGGLTQ 2396 L I N+S + ++G + CR+ T + +TV TPP +I V E + + + CS GG P P I+ Y N ++ + T A +S I + + V A+N+ L + T+ LN+ Y P+++ N + ++T L C V A P ++W + + I SS I ++ G C A N LG T E + L++L P++ I+S R + +I C VT+NP P I+W K ++S + L + G Y C NI S +R T+ L V ++P + I NK + + G + CS + PG P P +W +D E T+ I++ + + + + GKY C A NE+G T ++ +++ P + QH R+V + + TC +G+P +W +I P ++++ + + + + ++L +R +L G Y C N + S + + ++ ++ K+A + + ++ C+ ++ +W N L S + E++ D++T LK+N LT + D+ Y+C +N + + K P+ P +LR T+ + V+++W PGF+GGL++ Sbjct: 110 LQIKNVSYNRDNGRFECRIKAKGTGADVHQEFHNLTVLTPPHPPVISPG-NIAVATEDKPMELTCSSIGGSPDPTITWYREGSNTPLPATVLKGGTKDQPTNATLSIIPRREDDGAKYKCVVRNRAMNEGKRL-EATATLNVNYYPRVEVGPENPLRVERDRTAKLECNVDAKPKVPNVRW--NRNGRFISSSLVHTIHRVSVQDAGKYTCIADNGLGKTGEQELILDILYPPMVVIESKTREAEEGDTVTIRCNVTANPAPVTIEWLK-----ENSPDFRYNGDVLTLTSVRADHAGNYICRAVNIMQSQGMERSERVGNSTVALLVRHRPGQAYITPNKPV-VHVGNGVTLTCSAN--PPGWPVPQYRWFRDMDGEFSSTQKILAQGPQYSIPKAHLGNEGKYHCHAVNELGIGM-MATIVLEIHQPPQFLAKLQQHMTRRVADT------DYTVTCSAKGKPAPSVKWLKDAVEILPEENLYEVQTNPDQGLNGMVTVQSQLKFRGKAR--PNGNALVPGDRGLYTCLYQNE--VNSANSSMQLRIEHEPIVLHQYNKVAFDIRETAEVV-CKVQAYPKPEFQWQFGNNPSPLTMSSDGHY----EISTTTDNNDIYTSVLKINSLT-----HSDYGEYTCRVANTLDTIRAPIRLQQKGPPEKPTNLRATEVGHNYVSLSWDPGFDGGLSK 771
BLAST of hemicentin-1 isoform X2 vs. Ensembl Fly
Match: ed (gene:FBgn0000547 transcript:FBtr0077465) HSP 1 Score: 155.606 bits (392), Expect = 7.804e-38 Identity = 164/695 (23.60%), Postives = 296/695 (42.59%), Query Frame = 3 Query: 363 LTIHNISSD-NSGYYVCRVTLLTTSEHI-ISLAVVTVKTPPKSISFHFNKSINVFQEQEFIAIQCSVSGGIPPPKISMYIVKDNAIKRLKIISSNFPNS-TIAEVSAISLWRPHYLENRGFVMCTAINDAGVLTKNTSLLNIKYKPKIKPFVPNTVNAMINQTIDLSCEVYANP-AATIQWVIMQGLQIIDSS--KFIAKIRPDMDGPLICEAKNYLGSTKET-VQLNVLRDPLIHIDSNYR-VPKNSNYSINCRVTSNPPPEFIKWYKLSNMTDSSAVLISDDAKLNFILIDRSSTGMYACVTQNIQISTTGKRKPANSEKTMFLTVTYKPKEPQILGNKIISIMKGEKFIIKCSTDRKSPGEPFPTLKW---IDVE---TKDIVSDMETFQVINSESRHNGKYKCLAENEIGKSFSRETALVTVNEAPSIIT---QHKNRKVFLSYSDLPQSISFTCEFRGQPLYEARWRYGNEKIPPSSQDFKIEDHRNISNERISQIFTKLTIDLYSRTFSQQTSLRSSPNGRYNCEADNRHGIASLDYFLXXXXXXXXXXNIRHRKIAASLNQNVVMIRCQAESISTMHIKWYKTNEHIVLPFQSKKYSIFEAEVTKYEPERDLFTPGLKVNELTIKDLENDDFSNYSCVASNDQGIKKVNFEVVFKSQPDPPYDLRVTDFEWDSVTINWKPGFNGGLTQ 2396 L I N+S + ++G + CR+ T + +TV TPP +I V E + + + CS GG P P I+ Y N ++ + T A +S I + + V A+N+ L + T+ LN+ Y P+++ N + ++T L C V A P ++W + + I SS I ++ G C A N LG T E + L++L P++ I+S R + +I C VT+NP P I+W K ++S + L + G Y C NI S +R T+ L V ++P + I NK + + G + CS + PG P P +W +D E T+ I++ + + + + GKY C A NE+G T ++ +++ P + QH R+V + + TC +G+P +W +I P ++++ + + + + ++L +R +L G Y C N + S + + ++ ++ K+A + + ++ C+ ++ +W N L S + E++ D++T LK+N LT + D+ Y+C +N + + K P+ P +LR T+ + V+++W PGF+GGL++ Sbjct: 110 LQIKNVSYNRDNGRFECRIKAKGTGADVHQEFHNLTVLTPPHPPVISPG-NIAVATEDKPMELTCSSIGGSPDPTITWYREGSNTPLPATVLKGGTKDQPTNATLSIIPRREDDGAKYKCVVRNRAMNEGKRL-EATATLNVNYYPRVEVGPENPLRVERDRTAKLECNVDAKPKVPNVRW--NRNGRFISSSLVHTIHRVSVQDAGKYTCIADNGLGKTGEQELILDILYPPMVVIESKTREAEEGDTVTIRCNVTANPAPVTIEWLK-----ENSPDFRYNGDVLTLTSVRADHAGNYICRAVNIMQSQGMERSERVGNSTVALLVRHRPGQAYITPNKPV-VHVGNGVTLTCSAN--PPGWPVPQYRWFRDMDGEFSSTQKILAQGPQYSIPKAHLGNEGKYHCHAVNELGIGM-MATIVLEIHQPPQFLAKLQQHMTRRVADT------DYTVTCSAKGKPAPSVKWLKDAVEILPEENLYEVQTNPDQGLNGMVTVQSQLKFRGKAR--PNGNALVPGDRGLYTCLYQNE--VNSANSSMQLRIEHEPIVLHQYNKVAFDIRETAEVV-CKVQAYPKPEFQWQFGNNPSPLTMSSDGHY----EISTTTDNNDIYTSVLKINSLT-----HSDYGEYTCRVANTLDTIRAPIRLQQKGPPEKPTNLRATEVGHNYVSLSWDPGFDGGLSK 771
BLAST of hemicentin-1 isoform X2 vs. Ensembl Fly
Match: ed (gene:FBgn0000547 transcript:FBtr0334266) HSP 1 Score: 155.606 bits (392), Expect = 8.493e-38 Identity = 164/695 (23.60%), Postives = 296/695 (42.59%), Query Frame = 3 Query: 363 LTIHNISSD-NSGYYVCRVTLLTTSEHI-ISLAVVTVKTPPKSISFHFNKSINVFQEQEFIAIQCSVSGGIPPPKISMYIVKDNAIKRLKIISSNFPNS-TIAEVSAISLWRPHYLENRGFVMCTAINDAGVLTKNTSLLNIKYKPKIKPFVPNTVNAMINQTIDLSCEVYANP-AATIQWVIMQGLQIIDSS--KFIAKIRPDMDGPLICEAKNYLGSTKET-VQLNVLRDPLIHIDSNYR-VPKNSNYSINCRVTSNPPPEFIKWYKLSNMTDSSAVLISDDAKLNFILIDRSSTGMYACVTQNIQISTTGKRKPANSEKTMFLTVTYKPKEPQILGNKIISIMKGEKFIIKCSTDRKSPGEPFPTLKW---IDVE---TKDIVSDMETFQVINSESRHNGKYKCLAENEIGKSFSRETALVTVNEAPSIIT---QHKNRKVFLSYSDLPQSISFTCEFRGQPLYEARWRYGNEKIPPSSQDFKIEDHRNISNERISQIFTKLTIDLYSRTFSQQTSLRSSPNGRYNCEADNRHGIASLDYFLXXXXXXXXXXNIRHRKIAASLNQNVVMIRCQAESISTMHIKWYKTNEHIVLPFQSKKYSIFEAEVTKYEPERDLFTPGLKVNELTIKDLENDDFSNYSCVASNDQGIKKVNFEVVFKSQPDPPYDLRVTDFEWDSVTINWKPGFNGGLTQ 2396 L I N+S + ++G + CR+ T + +TV TPP +I V E + + + CS GG P P I+ Y N ++ + T A +S I + + V A+N+ L + T+ LN+ Y P+++ N + ++T L C V A P ++W + + I SS I ++ G C A N LG T E + L++L P++ I+S R + +I C VT+NP P I+W K ++S + L + G Y C NI S +R T+ L V ++P + I NK + + G + CS + PG P P +W +D E T+ I++ + + + + GKY C A NE+G T ++ +++ P + QH R+V + + TC +G+P +W +I P ++++ + + + + ++L +R +L G Y C N + S + + ++ ++ K+A + + ++ C+ ++ +W N L S + E++ D++T LK+N LT + D+ Y+C +N + + K P+ P +LR T+ + V+++W PGF+GGL++ Sbjct: 110 LQIKNVSYNRDNGRFECRIKAKGTGADVHQEFHNLTVLTPPHPPVISPG-NIAVATEDKPMELTCSSIGGSPDPTITWYREGSNTPLPATVLKGGTKDQPTNATLSIIPRREDDGAKYKCVVRNRAMNEGKRL-EATATLNVNYYPRVEVGPENPLRVERDRTAKLECNVDAKPKVPNVRW--NRNGRFISSSLVHTIHRVSVQDAGKYTCIADNGLGKTGEQELILDILYPPMVVIESKTREAEEGDTVTIRCNVTANPAPVTIEWLK-----ENSPDFRYNGDVLTLTSVRADHAGNYICRAVNIMQSQGMERSERVGNSTVALLVRHRPGQAYITPNKPV-VHVGNGVTLTCSAN--PPGWPVPQYRWFRDMDGEFSSTQKILAQGPQYSIPKAHLGNEGKYHCHAVNELGIGM-MATIVLEIHQPPQFLAKLQQHMTRRVADT------DYTVTCSAKGKPAPSVKWLKDAVEILPEENLYEVQTNPDQGLNGMVTVQSQLKFRGKAR--PNGNALVPGDRGLYTCLYQNE--VNSANSSMQLRIEHEPIVLHQYNKVAFDIRETAEVV-CKVQAYPKPEFQWQFGNNPSPLTMSSDGHY----EISTTTDNNDIYTSVLKINSLT-----HSDYGEYTCRVANTLDTIRAPIRLQQKGPPEKPTNLRATEVGHNYVSLSWDPGFDGGLSK 771
BLAST of hemicentin-1 isoform X2 vs. Ensembl Fly
Match: fred (gene:FBgn0051774 transcript:FBtr0308126) HSP 1 Score: 151.754 bits (382), Expect = 1.026e-36 Identity = 183/791 (23.14%), Postives = 318/791 (40.20%), Query Frame = 3 Query: 363 LTIHNISSD-NSGYYVCRVTLLTTS----EHIISLAVVTVKTPPKSISFHFNKSINVFQEQEFIAIQCSVSGGIPPPKISMYIVKDNAIKR---LKIISSN-FPNSTIAEVSAISLWRPHYLENRGFVMCTAINDA---GVLTKNTSLLNIKYKPKIKPFVPNTVNAMINQTIDLSCEVYANPAAT-IQWVIMQGLQIIDSSKFIAKIRPDMDGPLICEAKNYLGSTKET-VQLNVLRDPLIHIDS-NYRVPKNSNYSINCRVTSNPPPEFIKWYKLSNMTDSSAVLISDDAKLNFILIDRSSTGMYACVTQNIQISTTGKRKPANSEKTMFLTVTYKPKEPQILGNKIISIMKGEKFIIKCSTDRKSPGEPFPTLKWI-DVE-----TKDIVSDMETFQVINSESRHNGKYKCLAENEIGKSFSRETALVTVNEAPSIIT---QHKNRKVFLSYSDLPQSISFTCEFRGQPLYEARWRYGNEKIPPSSQDFKIEDHRNISNERISQIFTKLTIDLYSRTFSQQTSLRSSPNGRYNCEADNRHGIASLDYFLXXXXXXXXXXNIRHRKIAASLNQNVVMIRCQAESISTMHIKWYKTNEHIVLPFQSKKYSIFEAEVTKYEPERDLFTPGLKVNELTIKDLENDDFSNYSCVASNDQGIKKVNFEVVFKSQPDPPYDLRVTDFEWDSVTINWKPGFNGGLTQNYEIL-----------VISENFGTQNVPFYSDK----------------NENTLTITGLYPSTPYEIRIYAVNSIGRSLNSETVKCVTK 2582 L I N S + ++G + CR+ T + +L V+T PP ++ V E++ + + CS GG P P I+ Y + LK S N + N+T+ V P ++ C N A G + + + LN+ Y P+++ N + + L C V A P + ++W + I ++ G C A N LG T E + L+VL P++ I+S + + I C VT+NP P ++W K + + L + G Y C + NI + KR T+ L V ++P + I NK + + G + CS + PG P P +W D++ T+ I++ + + + GKY C A NE+G T ++ V++ P + QH R+V D+ ++ TC +G+P + RW +I P+ + F I + + + + L +R Q L + G Y C +N A+ L I++ PI+ + ++ K+A L ++ ++ C+ ++ +W N L S + E++ D++T L+ I L++ D+ Y C A N + + K P+ P +L++ + + +NW PGFNGG ++ +S+ G +P Y EN + L Y ++YA+NS G S S + TK Sbjct: 89 LQIKNTSYNRDNGRFECRIKAKGTGADVHQEFYNLTVLTAPHPPMVTP----GNLAVATEEKPLELTCSSIGGSPDPMITWYREGSTVPLQSYALKGGSKNHYTNATLQIV-------PRRADDGAKYKCVVWNRAMPEGHMLETSVTLNVNYYPRVEVGPQNPLKVERDHVAKLDCRVDAKPMVSNVRWSRNGQYVSATPTHTIYRVNRHHAGKYTCSADNGLGKTGEKDIVLDVLYPPIVFIESKTHEAEEGETVLIRCNVTANPSPINVEWLK-----EGAPDFRYTGELLTLGSVRAEHAGNYICRSVNIMQPFSSKRVEGVGNSTVALLVRHRPGQAYITPNKPV-VHVGNGVTLTCSAN--PPGWPVPQYRWFRDMDGDIGNTQKILAQGPQYSIPKAHLGSEGKYHCHAVNELGIG-KIATIILEVHQPPQFLAKLQQHMTRRV----GDVDYAV--TCSAKGKPTPQIRWIKDGTEILPTRKMFDIRTTPTDAGGGVVAVQSILRFRGKARPNGNQ--LLPNDRGLYTCLYENDVNSANSSMHLRIEHEPIVIH--QYNKVAYDLRESAEVV-CRVQAYPKPEFQWQYGNNPSPLTMSSDGHY----EISTRMENNDVYTSILR-----IAHLQHSDYGEYICRAVNPLDSIRAPIRLQPKGSPEKPTNLKILEVGHNYAVLNWTPGFNGGFMSTKYLVSYRRVATPREQTLSDCSGNGYIPSYQISSSSSNSNHEWIEFNCFKENPCKLAPLDQHQSYMFKVYALNSKGTSGYSNEILATTK 839
BLAST of hemicentin-1 isoform X2 vs. Ensembl Fly
Match: fred (gene:FBgn0051774 transcript:FBtr0308125) HSP 1 Score: 150.984 bits (380), Expect = 2.295e-36 Identity = 183/791 (23.14%), Postives = 318/791 (40.20%), Query Frame = 3 Query: 363 LTIHNISSD-NSGYYVCRVTLLTTS----EHIISLAVVTVKTPPKSISFHFNKSINVFQEQEFIAIQCSVSGGIPPPKISMYIVKDNAIKR---LKIISSN-FPNSTIAEVSAISLWRPHYLENRGFVMCTAINDA---GVLTKNTSLLNIKYKPKIKPFVPNTVNAMINQTIDLSCEVYANPAAT-IQWVIMQGLQIIDSSKFIAKIRPDMDGPLICEAKNYLGSTKET-VQLNVLRDPLIHIDS-NYRVPKNSNYSINCRVTSNPPPEFIKWYKLSNMTDSSAVLISDDAKLNFILIDRSSTGMYACVTQNIQISTTGKRKPANSEKTMFLTVTYKPKEPQILGNKIISIMKGEKFIIKCSTDRKSPGEPFPTLKWI-DVE-----TKDIVSDMETFQVINSESRHNGKYKCLAENEIGKSFSRETALVTVNEAPSIIT---QHKNRKVFLSYSDLPQSISFTCEFRGQPLYEARWRYGNEKIPPSSQDFKIEDHRNISNERISQIFTKLTIDLYSRTFSQQTSLRSSPNGRYNCEADNRHGIASLDYFLXXXXXXXXXXNIRHRKIAASLNQNVVMIRCQAESISTMHIKWYKTNEHIVLPFQSKKYSIFEAEVTKYEPERDLFTPGLKVNELTIKDLENDDFSNYSCVASNDQGIKKVNFEVVFKSQPDPPYDLRVTDFEWDSVTINWKPGFNGGLTQNYEIL-----------VISENFGTQNVPFYSDK----------------NENTLTITGLYPSTPYEIRIYAVNSIGRSLNSETVKCVTK 2582 L I N S + ++G + CR+ T + +L V+T PP ++ V E++ + + CS GG P P I+ Y + LK S N + N+T+ V P ++ C N A G + + + LN+ Y P+++ N + + L C V A P + ++W + I ++ G C A N LG T E + L+VL P++ I+S + + I C VT+NP P ++W K + + L + G Y C + NI + KR T+ L V ++P + I NK + + G + CS + PG P P +W D++ T+ I++ + + + GKY C A NE+G T ++ V++ P + QH R+V D+ ++ TC +G+P + RW +I P+ + F I + + + + L +R Q L + G Y C +N A+ L I++ PI+ + ++ K+A L ++ ++ C+ ++ +W N L S + E++ D++T L+ I L++ D+ Y C A N + + K P+ P +L++ + + +NW PGFNGG ++ +S+ G +P Y EN + L Y ++YA+NS G S S + TK Sbjct: 89 LQIKNTSYNRDNGRFECRIKAKGTGADVHQEFYNLTVLTAPHPPMVTP----GNLAVATEEKPLELTCSSIGGSPDPMITWYREGSTVPLQSYALKGGSKNHYTNATLQIV-------PRRADDGAKYKCVVWNRAMPEGHMLETSVTLNVNYYPRVEVGPQNPLKVERDHVAKLDCRVDAKPMVSNVRWSRNGQYVSATPTHTIYRVNRHHAGKYTCSADNGLGKTGEKDIVLDVLYPPIVFIESKTHEAEEGETVLIRCNVTANPSPINVEWLK-----EGAPDFRYTGELLTLGSVRAEHAGNYICRSVNIMQPFSSKRVEGVGNSTVALLVRHRPGQAYITPNKPV-VHVGNGVTLTCSAN--PPGWPVPQYRWFRDMDGDIGNTQKILAQGPQYSIPKAHLGSEGKYHCHAVNELGIG-KIATIILEVHQPPQFLAKLQQHMTRRV----GDVDYAV--TCSAKGKPTPQIRWIKDGTEILPTRKMFDIRTTPTDAGGGVVAVQSILRFRGKARPNGNQ--LLPNDRGLYTCLYENDVNSANSSMHLRIEHEPIVIH--QYNKVAYDLRESAEVV-CRVQAYPKPEFQWQYGNNPSPLTMSSDGHY----EISTRMENNDVYTSILR-----IAHLQHSDYGEYICRAVNPLDSIRAPIRLQPKGSPEKPTNLKILEVGHNYAVLNWTPGFNGGFMSTKYLVSYRRVATPREQTLSDCSGNGYIPSYQISSSSSNSNHEWIEFNCFKENPCKLAPLDQHQSYMFKVYALNSKGTSGYSNEILATTK 839
BLAST of hemicentin-1 isoform X2 vs. Ensembl Zebrafish
Match: hmcn1 (hemicentin 1 [Source:ZFIN;Acc:ZDB-GENE-041014-322]) HSP 1 Score: 110.153 bits (274), Expect = 1.471e-23 Identity = 157/688 (22.82%), Postives = 283/688 (41.13%), Query Frame = 3 Query: 327 SESQITISHESRLT-IHNISSDNSGYYVCRVTLLTTSEHIISLAVVTVKTPPKSISFHFNKSINVFQEQEFI-----AIQCSVSGGIPPPKISMYIVKDNAIKRLKIISSN-----FPNSTIAEVSAISLWRPHYLENRGFVMCTAINDAGVLTKNTSLLNIKYKPKIKPF---VPNTVNAMINQTIDLSCEVYANPAATIQWVI-MQGLQIIDSSKFIAKIRPDM--------DGPLICEAKNYLGSTKETVQLNVLRDPLIHI--DSNYRVPKNSNYSINCRVTSNPPPEFIKWYKLSNMTDSS--AVLISDDAKLNFILIDRSSTGMYACVTQNIQISTTGKRKPAN-SEKTMFLTVTYKPKEPQILGN--KIISIMKGEKFIIKCSTDRKSPGEPFPTLKWID-----VETKD--IVSDMETFQVINSESRHNGKYKCLAENEIG---KSFSRETALVTVNEAPSIITQHKNRKVFLSYSDLPQSISFTCEFRGQPLYEARWRYGNEKIPPSSQDFKIEDHRNISNERISQIFTKLTIDLYSRTFSQQTSLRS--SPNGRYNCEADNRHGIASLDYFLXXXXXXXXXXNIRHRKIAASLNQNVVMIRCQAESISTMHIKWYKTNEHIVLPFQSKKYSIFEAEVTKYEPERDLFTPGLKVNELTIKDLENDDFSNYSCVASNDQG 2264 ++ +TI+ R+ I + ++G Y C T + + V ++ PP F + N + ++ I ++ C + +PPP ++ Y K +++SN P + ++ + ++ G C A+N+AG + + + P I+ +P+ V ++N+T+ L C+V +P I WV Q L ++ + ++ R G +C A+N G+ +++ L+V P I + N V N+ S+NC T PPP ++W+K +S A+++ L + S G Y+CV N PA ++K ++LTV P G+ ++++ G+ +++C ++ P P + W ET + I++D + Q+ +E G+Y C A N G K+F + ++ P + + R V + ++F C+ G IPP S + + N R+ + L + + S Q S RS S +G Y C A N G A +Y L+I PP I + +++ LN +V ++ C+AE T I+W K I Q K P+ + LT+ + D Y+CVA+N G Sbjct: 2706 ADGHLTITANGRIVQIKHTQVSDTGRYTCVATNIAGEDE--KDFDVNIQVPPSFRGFGDSGPGNNGEVKDVILNNPISLYCETNA-VPPPVLTWY-------KDGHLLTSNDKVLILPGGRVLQIPRAQV------DDTGRYTCVAVNEAGEDSIQYDV-RVLLPPSIRGADGELPDEVTVLVNKTMLLECQVDGSPTPKISWVKDSQPLTQDNTHRLLSNGRTLQILNAQVTDTGRYVCVAQNLAGTAEKSFNLHVHVSPTIVGIREENVTVVLNNFVSLNCEATGLPPPT-LRWFKDRRPVQASTNALIMPGGRTLQILKAKMSDGGKYSCVAVN----------PAGEAQKLIYLTVYVPPSIRHNSGDLPVVLNVQVGKSVMLECESNAVPP----PVITWYKNGRPIAETANLRILADGQMLQLKETEVSDTGQYVCKATNVAGQVDKNFH-----LNIHVPPRLDGPAEERVV----ETISNPVTFACDATG--------------IPPPSLTW-------LKNGRVIENSESLEMHILSGGSKLQIS-RSQLSDSGTYTCVASNVEGKAQKNYHLVIHVPPNIIGSELPSEMSVLLNDSVQLV-CRAEGTPTPEIQWLKDGMTISRTAQKN---------IKISPDG---------STLTVTAVHTSDSGKYTCVATNQAG 3311 HSP 2 Score: 100.138 bits (248), Expect = 1.491e-20 Identity = 152/680 (22.35%), Postives = 251/680 (36.91%), Query Frame = 3 Query: 363 LTIHNISSDNSGYYVCRVTLLTTSEHIISLAVVTVKTPPKSISFHFNKSINVFQEQEFIAIQCSVSGGIPPPKISMYIVKDNAIKRLKII--SSNFPNSTIAEVSAISLWRPHYLENRGFVMCTAINDAGVLTKNTSLLNIKYKPKI-KPFVPNTVNAMINQTIDLSCEVYANPAATIQWVIMQGLQIIDSSKFIAKIRPDMD------------GPLICEAKNYLGSTKETVQLNVLRDPLIHIDSNYRVPK------NSNYSINCRVTSNPPPEFIKWYK--LSNMTDSSAVLISDDAKLNFILIDRSSTGMYACVTQNIQISTTGKRKPANSEKTMFLTVTYKPKEPQILGNKIISIMKGEKFIIKCSTDRKSPGEPFPTLKWIDVE---TKD----IVSDMETFQVINSESRHNGKYKCLAENEIGKSFSRETALVTVNEAPSIITQHKNRKVFLSYSDLPQSISFTCEFRGQPLYEARWRYGNEKIPPSSQDFKIEDHRNISNERISQIFTKLTIDLYSRTFSQQTSLRSSPNGRYNCEADNRHGIASLDYFLXXXXXXXXXXNIRHRKIAASLNQNVVMIRCQAESISTMHIKWYKTNEHIVLPFQSKKYSIFEAEVTKYEPERDLFTPG--LKVNELTIKDLENDDFSNYSCVASNDQGIKKVNFEVVFKSQP 2306 L + ++G YVC+ T + + + + PP+ + + + C +G IPPP ++ +K ++I S + ++ S + + R L + G C A N G KN L+ I P I +P+ ++ ++N ++ L C P IQW + G+ I +++ KI PD G C A N G LNV PLI N K +S+ +I C + +PPP+ + W K L S L+S L S G Y CV N + + L V P + ++++KG C D G P P + W+ +KD +++ T Q++N H G+Y C A N+ G + SR +L V + P I +V + + + + CE G PL W +P + NI R Q+ R S Q GRY C A + G + FL+ + P R + + L V + C+++++ + W K + + K P + + G L++N + D + YSCVASN G + +F++ P Sbjct: 3100 LQLKETEVSDTGQYVCKAT--NVAGQVDKNFHLNIHVPPRLDGPAEERVVETISNP--VTFACDATG-IPPPSLTW-------LKNGRVIENSESLEMHILSGGSKLQISRSQ-LSDSGTYTCVASNVEGKAQKNYHLV-IHVPPNIIGSELPSEMSVLLNDSVQLVCRAEGTPTPEIQW-LKDGMTISRTAQKNIKISPDGSTLTVTAVHTSDSGKYTCVATNQAGEEDRIFNLNVYVPPLIQ--GNGPAAKELTTVLDSSINIECVASGSPPPQ-LNWLKNGLPLPVSSQIRLLSAGQVLRIARAQVSDGGSYTCVASN---------RAGVDNRHYTLQVYVPPSLDGAGSTEEVTVVKGSTASFICIAD----GTPSPVIIWLRTGASVSKDAHISLLNQNSTMQIVNVLVNHTGRYTCTAHNQAGDA-SRHFSL-KVLDPPRINGSGVPAEVSVVVNHV---LELLCEADGIPLPTLTWLKDGRPLPQT---------ENIRLLRDGQML---------RVASAQV----ENTGRYTCLASSPAGDDDKE-FLVRVHVPPNIAGDRGVQDVSVLQNRQVTLECKSDAVPPPTLTWLKDDAPL-----------------KMSPRVRVLSSGRYLQINNAVL-----GDGAQYSCVASNVAGETRRHFKLSVNVPP 3698 HSP 3 Score: 93.5893 bits (231), Expect = 1.460e-18 Identity = 152/708 (21.47%), Postives = 265/708 (37.43%), Query Frame = 3 Query: 318 VPDSESQITISHESRLTIHNISSDNSGYYVCRVTLLTTSEHIISLAVVTVKTPPKSISFHFNKSINVFQEQEFIAIQCSVSGGIPPPKISMYIVKDNAIK---RLKIISSN----FPNSTIAEVSAISLWRPHYLENRGFVMCTAINDAGVLTKNTSLLNIKYKPKIKPFVPNTVNAMINQTIDLSCEVYANPAATIQWVIMQGLQII----------DSSKFIAKIRPDMDGPLICEAKNYLGSTKETVQLNVLRDPLI-HIDSNYRVPKNSNYSINCRVTSNPPPEFIKWYK----LSNMTDSSAVLISDDAKLNFILIDRSSTGMYACVTQNIQISTTGKRKPANSEKTMFLTVTYKPKEPQILGNKIISIMKGEKFIIKCSTDRKSPGEPFPTLKWIDVETKD---IVSDMETFQVINS--------ESRHNGKYKCLAENEIGKSFSRETALVTVNEAPSIITQHKNRKVFLSYSDLPQSISFTCEFRGQPLYEARWRYGNEKIPPSSQDFKIEDHRNISNERISQIFTKLTIDLYSRTFSQQTSLRSSPNGRYNCEADNRHGIASLDYFLXXXXXXXXXXNIRHRKIAASLNQNVVMIRCQAESISTMHIKWYKTNEHIVLPFQSKKYSIFEAEVTKYEPERDLFTPGLKVNELTIKDLENDDFSNYSCVASNDQGIKKVNFEVVFKSQPDPPYDLRVTDFE 2342 +P +E+ + L + + +N+G Y C + + L V V PP + ++V Q ++ + ++C S +PPP ++ ++ D +K R++++SS N+ + + + S C A N AG T+ L++ P IK P +V+ INQ + L C V PA I W QG + D S I + G +C A N G+ ++ V L V P I +N V N +++C T P P + W K L+ + + + L I T +Y CV N + + + LTV P ++S + +I C+ G P P L W +KD + D E F ++ S + H+G+Y C+A+N G + R L TV+E+P I + V L+ ++ C G P W+ I + F + + + Q + + +G Y C A N G A L ++ PP+I +IR +A ++ V ++C +E T + W+K + + + + S ++ +P D Y+C +N G ++ + + P +RV + E Sbjct: 3554 LPQTENIRLLRDGQMLRVASAQVENTGRYTCLASSPAGDDDKEFL--VRVHVPPNIAGDRGVQDVSVLQNRQ-VTLECK-SDAVPPPTLT-WLKDDAPLKMSPRVRVLSSGRYLQINNAVLGDGAQYS--------------CVASNVAGE-TRRHFKLSVNVPPTIKDG-PQSVSVHINQPVVLECVVNGVPAPRITWR-KQGSILAGNNPRYKFGEDGSLRILSAQVTDTGRYLCMATNQAGTERKRVDLQVYVPPSIAEGPTNITVTVNVQTTLSCEATGIPKPS-VSWTKNTQALNTDQNQNMYRLLSSGSLVVIAPSVEDTALYECVVSN---------EAGQESRAIQLTVHVPPSIADEATELVVSRLS--PVVIGCTAS----GVPHPVLYW----SKDGLRLAKDGEGFTILPSGPLEITAADLSHSGRYSCVAKNAAGTAH-RHVQL-TVHESPVIQSHPSTLDVILN-----NHVTLPCRATGSPRPTITWQKEGINIFTTGGGFTVLPNGGL----------------------QISKAKVEDSGTYMCVAQNPAGTALGKTKLRVQVPPVITSDIRAYTVALDVS---VTLQCNSEGFPTPSVSWHKDGQLLSESVRQRVLSTGALQIAFAQP---------------------GDTGRYTCTVANVAGSSSLDISLTVQIPP----SIRVGESE 4162 HSP 4 Score: 88.1965 bits (217), Expect = 6.747e-17 Identity = 151/635 (23.78%), Postives = 247/635 (38.90%), Query Frame = 3 Query: 327 SESQITISHESRLTIHNISSDNSGYYVCRVTLLTTSEHIISLAVVTVKTPPKSISFHFNKSINVFQEQ---------EFIAIQCSVSGGIPPPKISMYIVKDNAIKRLKIISSNFPNSTIAEVSAISLWRPHYLENRGFVMCTAINDAGVLTKNTSLLNIKYKPKIKPFVPNTVNAMINQTIDLSCEVYANPAATIQW-----VIMQG--LQIIDSSKFIAKIRPDMDGPLICEAKNYLGSTKETVQLNVLRDPLIHI-DSNYRVP-----KNSNYSINCRVTSNPPPEFIKWYKLSN--MTDSSAVLISDDAKLNFILIDRS--STGMYACVTQNIQISTTGKRKPANSEKTMFLTVTYKP--KEPQILGNKIISIMKGEKFIIKCSTDRKSPGEPFPTLKWID-----VETKD--IVSDMETFQVINSESRHNGKYKCLAENEIGKSFSRETAL-VTVNEAPSIITQHKNRKVFLSYSDLPQSISFTCEFRGQPLYEARWRYGNEKIPPSSQDFKIEDHRNISNERISQIFTKLTIDLYSRTFSQQTSLRSSPNG---RYNCEADNRHGIASLDYFLXXXXXXXXXXNIRHRKIAASLNQNVVMIRCQAESISTMHIKWYKTNEHIVLPFQSK 2114 S S +++ + L IH+ S + SG +VC T + + +TV PK +S I+ E+ + I + C V +PPP I+ KD K + S F I S + + G +C A N AG ++ T L++ P I P + I IDL C P ++ W V+ G +I D + + ++ +G +C A N G + +QL+V P++ + + + P N + C P P IKW++ + + V I +D L IL S G Y C+ N +EK L V P ++ +L N + I + + + G P P + W V + D I+ +T +++ + + G+Y C A N G SRE + V P+II +R + + L Q I C+ +G P +W +K +R I++ +R QQ ++S+ G RY C A N G S D+ L I PP IK ++ L N+V + C+ + + WYK E I+ Q++ Sbjct: 1016 SGSVFSLTEDGSLHIHSPSGEESGEFVCTAT--NAAGYSSRKVQLTVYVRPK-LSGVGEADIHDNSEKLLEMSVIVGDDITLPCEVES-VPPPIITW--AKD------KQLISPFSPRHIQLPSGSMRITDTRVTDSGMYLCVATNIAGNFSQ-TVKLSVLVPPSISAG-PRAMKVQIGHAIDLPCVTQGVPEPSVSWLKDGTVLQDGSRYRISDGALTLNQVALTDEGIYVCRAVNIAGKEETAIQLHVQVPPVVEVSEPPFNSPLQERVANQQIAFPCPAKGTPEP-VIKWFRNGHELTGNEPGVSILEDGTL-LILASVSPLDNGEYTCMAVN---------DAGTTEKKYQLKVNVPPDIRDNGLLSNVSVVINQPTNLVCDVT------GTPVPVITWYKDGVEVVPSSDVQILQKGKTLKLLKAAVQDAGRYICKAINIAG---SRERDFYLDVLVPPTIIGTVGSRDL---SAVLNQEIVLECKVKGDPFPTIQW-------------YK---------DRKPVFLGDPNIEVLNR--GQQLKIKSARLGDQARYQCSATNAAGKQSKDFNLSIFVPPSIKGGNVSSEVTVLLG-NLVTLECEVRGVPLPAVTWYKNGEVILSSRQAQ 1588 HSP 5 Score: 88.1965 bits (217), Expect = 6.978e-17 Identity = 155/692 (22.40%), Postives = 270/692 (39.02%), Query Frame = 3 Query: 330 ESQITISHESRLTIHNISSDNSGYYVCRVTLLTTSEHIISLAVVTVKTPPKSISFHFNKSINVFQEQEFIAIQCSVSGGIPPPKISMYIVKDNA-IKRLKI--ISSNFPNSTI--AEVSAISLWRPHYLENRGFVMCTAINDAGVLTKNTSLLNIKYKPKIKPFVPNTVNAMINQTIDLSCEVYANPAATIQWVIMQGLQIIDSSKF-----------IAKIRPDMDGPLICEAKNYLGSTKETVQLNVLRDPLIHIDS---NYRVPKNSNYSINCRVTSNPPPEFIKWYKLSNMTDSSAVLISDDAKLNFILIDR---SSTGMYACVTQNIQISTTGKRKPANSEKTMFLTVTYKPKEPQILGNKIISIMKGEKFIIKCSTDRKSPGEPFPTLKWIDVETK--------DIVSDMETFQVINSESRHNGKYKCLAENEIGKSFSRETALVTVNEAPSIITQHKNRKVFLSYSDLPQSISFTCEFRGQPLYEARWRYGNEKIPPSSQDFKIEDHRNISNERISQIFTKLTIDLY-SRTFSQQTSLRSSPNGRYNCEADNRHGIASLDYFLXXXXXXXXXXNIRHRKIAASLN---QNVVMIRCQAESISTMHIKWYKTNEHIVLPFQSKKYSIFEAEVTKYEPERDLFTPGLKVNELTIKDLENDDFSNYSCVASNDQG--IKKVNFEVVFK 2297 ES + ++ I N ++G YVC T + + I V+V PP V + ++C +G P P I+ +KD +K + I+SN I A+VS +L+ C A N+AG + + ++ P I+ P + +++ +I L C V P + W + G + + +F I K R + G C A N G ++ ++L+V P I N + + C+ T +P P + WYK +SA ++ ++ + + IDR S G Y CV N+ ST E T L V P G +++++ + ++C ++ G P P+L W+ + ++S I+++ G Y C+A N G+ RE L V P+I+ + N V + QS+ C+ ++ IPP + ++ +D R ++ K + + +F + S + GRY CEA N G Y L + PP +IR +SL ++ + C++ I + W K + K + + + G +L I E D S+Y+C+AS+ G IK+ N +V + Sbjct: 1679 ESLRVLDQGRKIEILNALQSDAGRYVCVATSVAGEKEI--KYDVSVLVPPVVDGASDTTDATVILNN-ILELECYATG-RPTPTITW--LKDGVPVKHGEGVRITSNGRRLVISRAQVSDTALFH-----------CVATNEAGEQEREFKV-SVHVPPAIRSTGPAERSVVLHTSISLQCVVSGIPPPSTTW-LKDGRPVDTTQEFLKLESAGRVLHIKKARLEDAGKYTCVATNAAGEAQQHIRLSVHEPPSIQYAGEMLNETILAGFQIQLKCKATGSPLPA-VTWYK-DGRPLTSAAGVNILSRGHVLEIDRAQVSDAGFYKCVAINVAGST---------ELTYSLQVYVPPTISSKGG--MVTVVVNDPVRLEC----EASGVPVPSLTWLKEGSPVSSFSDGIQVLSGGRVLSFISAQVSDAGHYTCVAVNAGGEQH-REYEL-RVYVPPNIMGEEVNNTVLMG-----QSVQLHCQ--------------SDAIPPPALSWR-KDGR--------PLYRKPGLSVSEDGSFLKIISAQVQDTGRYTCEATNVAGKTEKHYNLNVWVPP----SIRGSDEVSSLTVIEGGLITLVCESSGIPPPSLIWKKDGSEL-----------------KGDSRVRVLSGG---RQLQISSAEKADASSYTCLASSAAGSAIKEYNLQVYVR 2280 HSP 6 Score: 85.8853 bits (211), Expect = 3.287e-16 Identity = 154/700 (22.00%), Postives = 254/700 (36.29%), Query Frame = 3 Query: 363 LTIHNISSDNSGYYVCRVTLLTTSEHIISLAVVTVKT----------------PPKSISFHFNKSINVFQEQEFIAIQCSVSGGIPPPKISMYIVKDNAIKRLKIISSNFPNSTIAEVSAISLWRPHYLENRGFVMCTAINDAGVLTKNTSLLNIKYKPKIKPFVPN-------TVNAMINQTIDLSCEVYANPAATIQW-------------VIMQGLQIIDSSKFIAKIRPDMDGPLICEAKNYLGSTKETVQLNVLRDPLIHIDSNYRVPK------NSNYSINCRVTSNPPPEFIKWYKLSN--MTDSSAVLISDDAKLNFILIDRSSTGMYACVTQNIQISTTGKRKPANSEKTMFLTVTYKPKEPQILGNKIISIMKGEKFIIKCSTDRKSPGEPFPTLKW------IDVETKD-IVSDMETFQVINSESRHNGKYKCLAENEIGKSFSRETALVTVNEAPSIITQHKNRKVFLSYSDLPQSISFTCEFRGQPLYEARWRYGNEKIPPSSQDFKIEDHRNISNERISQIFTKLTIDLYSRTFSQQTSLRSSPNGRYNCEADNRHGIASLDYFLXXXXXXXXXXNIRHRKIAASLNQNVVMIRCQAESISTMHIKWYKTNEHIVLPFQSKKYSIFEAEVTKYEPERDLFTPGLKVNELTIKDLENDDFSNYSCVASNDQGIKKVNFEVVFKSQPD 2309 L I N +++G Y C + T+E +L VK PK + N ++ + E + IP P + Y KD I + + N I ++ + + G C A N AG K+ + NI+ P + F + + ++N I L CE A P + W +I+ G +++ I + + D G C A N G + VL P I ++ +P N + C+V +P P+ I W K S D++ L+S+ L + + TG Y CV QN+ +EK+ L V P I + ++ F+ S + ++ G P PTL+W + T I+ T Q++ ++ GKY C+A N G++ ++ +TV PSI + V L+ + +S+ CE P W Y N + + + +I L Q S G+Y C+A N G ++ L I PP + R + N V C A I + W K N ++ +S + I ++L I + D Y+CVASN +G + N+ +V P+ Sbjct: 2620 LQILNAKEEDAGRYTC----VATNEAGETLKNYEVKVFVPPVINKNDIPGESLAPKEVKIKVNNTLTLECEAQ----------AIPTPTLVWY--KDGQILKADGHLTITANGRIVQIKHTQV------SDTGRYTCVATNIAGEDEKDFDV-NIQVPPSFRGFGDSGPGNNGEVKDVILNNPISLYCETNAVPPPVLTWYKDGHLLTSNDKVLILPGGRVLQ----IPRAQVDDTGRYTCVAVNEAGEDSIQYDVRVLLPPSIR-GADGELPDEVTVLVNKTMLLECQVDGSPTPK-ISWVKDSQPLTQDNTHRLLSNGRTLQILNAQVTDTGRYVCVAQNLA---------GTAEKSFNLHVHVSPTIVGIREENVTVVLN--NFV---SLNCEATGLPPPTLRWFKDRRPVQASTNALIMPGGRTLQILKAKMSDGGKYSCVAVNPAGEA--QKLIYLTVYVPPSIRHNSGDLPVVLNV-QVGKSVMLECESNAVPPPVITW-YKNGRPIAETANLRI---------------------LADGQMLQLKETEVSDTGQYVCKATNVAGQVDKNFHLNIHVPPRLDGPAEERVVETI--SNPVTFACDATGIPPPSLTWLK-NGRVIENSESLEMHILSGG-----------------SKLQISRSQLSDSGTYTCVASNVEGKAQKNYHLVIHVPPN 3231 HSP 7 Score: 85.8853 bits (211), Expect = 3.761e-16 Identity = 150/670 (22.39%), Postives = 262/670 (39.10%), Query Frame = 3 Query: 381 SSDNSGYYVCRVTLLTTSEHIISLAV-VTVKTPPKSISFHFNKSINVFQEQEFIAIQCSVSGGIPPPKISMYIVKDNAIKRLKIISSNF---PNSTIAEVSAISLWRPHYLENRGFVMCTAINDAGVLTKNTSLLNIKYKPKIKPFVPNTVNAMINQTIDLSCEVYANPAATIQW--------VIMQGLQIIDSSKF-IAKIRPDMDGPLICEAKNYLGSTKETVQLNVLRDPLIHID-SNYRVPKNSNYSINCRVTSNPPPEFIKWYKLSNM-TDSSAVLISDDAKLNFILIDRSSTGMYACVTQNIQISTTGKRKPANSEKTMFLTVTYKPKEPQILGNKIISIMKGEKFIIKCSTDRKSPGEPFPTLKW--IDVETKDIVSD---METFQVI--NSESRHNGKYKCLAENEIGKSFSRETALVTVNEAPSI------ITQHKNRKVFLSYSDLPQSISFTCEFRGQPLYEARWRYGNEKIPPSSQDFKIEDHRNISNERISQIFTKLTIDLYSRTFSQQTSLRSSPNGRYNCEADNRHG-IASLDYFLXXXXXXXXXXNIRHRKIAASLNQNVVMIRCQAESISTMHIKWYKTNEHIVLPFQSKKYSIFEAEVTKYEPERDLFTPGLKVNELTIKDLENDDFSNYSCVASNDQGIKKVNFEVVFKSQ 2303 S +++ Y C V+ E S A+ +TV PP S + V + I C+ SG +P P +Y KD RL F P+ + E++A L + G C A N AG ++ L + P I+ P+T++ ++N + L C +P TI W G ++ + I+K + + G +C A+N G+ +L V P+I D Y V + + ++ C P P + W+K + ++S + L TG Y C N+ +S + LTV P +G +S+++ + ++ C D G P PT+ W D+ D ++ + T ++ ++ +G Y C+ N +G+ SR +L +++ P+ + +K ++ + C G P + W + N +P DH N +E L I+ S+ S G Y C A+N G I SL F+ +K PPII ++ +I L N ++ C+ I+W K ++ + + ++ L L I ++D NY CVA+ND G+ + + +S+ Sbjct: 3852 SVEDTALYECVVSNEAGQE---SRAIQLTVHVPP---SIADEATELVVSRLSPVVIGCTASG-VPHP--VLYWSKDGL--RLAKDGEGFTILPSGPL-EITAADL------SHSGRYSCVAKNAAGTAHRHVQL-TVHESPVIQSH-PSTLDVILNNHVTLPCRATGSPRPTITWQKEGINIFTTGGGFTVLPNGGLQISKAKVEDSGTYMCVAQNPAGTALGKTKLRVQVPPVITSDIRAYTVALDVSVTLQCNSEGFPTPS-VSWHKDGQLLSESVRQRVLSTGALQIAFAQPGDTGRYTCTVANVA---------GSSSLDISLTVQIPPS--IRVGESEVSVVENTQALLTCVAD----GVPQPTITWEKDDIPLTDTTAEYTILPTGDLLIDTAQPEDSGSYTCVGTNSMGQD-SRTISL-SIHTHPAFTELLGDVALNKRERLLM-----------VCGVTGIPPPKITWTFNNNIVPAQY------DHYNGHSE--------LVIERVSKDDS----------GTYTCMAENSVGSIKSLG-FVYVKEPPIIDGDVHSNRIEP-LGGNAIL-NCEVRGDPLPTIQWSKKGINVQISNRIRQ---------------------LDNGSLAIYGTVSEDAGNYMCVATNDAGVVERTVTLTLQSK 4424 HSP 8 Score: 80.8777 bits (198), Expect = 1.139e-14 Identity = 138/647 (21.33%), Postives = 245/647 (37.87%), Query Frame = 3 Query: 537 IAIQCSVSGGIPPPKISMYIVKDNAIKRLKIISSNFPNSTIAEVSAISLWRPHYLENRGFVMCTAINDAGVLTKNTSLLNIKYKPKI--KPFVPNTVNAMINQTIDLSCEVYANPAATIQWVIMQGLQIIDSSKFIAKIRPDMD-----------GPLICEAKNYLGSTKETVQLNVLRDPLIHIDS---NYRVPKNSNYSINCRVTSNPPPEFIKWYKLSN--MTDSSAVLISDDAKLNFILIDRSSTGMYACVTQNIQISTTGKRKPANSEKTMFLTVTYKPKEPQILGNKIISIMKGEKFIIKCSTDRKSP--------GEPFPTLKWIDVETKDIVSDMETFQVINSESRHNGKYKCLAENEIGKSFSRETALVTV------NEAPSIITQHKNRKVFLSYSDLPQSISFTCEFRGQPLYEARWRYGNEKIPPSSQDFKIEDHRNI-SNERISQIFTKLTIDLYSRTFSQQTSLRSSPNGRYNCEADNRHGIASLDYFLXXXX-----XXXXXXNIRHRKIAASLNQNVVMIRCQAESISTMHIKWYKTNEHIVLPFQSKKYSIFEAEVTKYEPERDLFTPGLKVNELTIKDLENDDFSNYSCVASNDQGIKKVNFEVVFKSQPDPPYDLRVTDFEW-DSVTI 2360 I ++C G +P P +S +K + +S+ + E + + + + G C AIN AG + + N+ P I + +P ++ ++ + L+CE P I W ++ Q I +S + I G C N G ++ L VL P I + + +V + N + C VT NP PE I W K +D+ ++S+ L + TG Y+C+ N + G R + + ++ T P+ ++ + ++ C P G PF + + + V + T Q++N++ G+Y C+A NE G++ V V N+ P K K+ ++ +++ CE + P W Y + +I K + H I +N RI QI + T + S GRY C A N G D+ + I+ + ++ + N + + C+ ++ + WYK + H++ ++ L PG +V L I + DD Y+CVA N+ G + ++V P +R D E D VT+ Sbjct: 2299 ITLRCEADG-VPRPAVSW-------MKDGRPLSTGRKAQILNEGRLLRILEAQ-VADTGRYTCIAINVAGQADRKYDV-NVHVPPTIIGQTHMPENISVVVKNPVVLTCEASGMPPPAITW--LKDGQPISTSSSVRVISGGRGLRLMHAASSDAGRYTCIVSNSAGEERKNFDLYVLVPPSIVNEGTVEDVKVKERQNAILACEVTGNPVPE-ITWLKDGQPLASDTRLQVMSNGRFLQISASQVADTGRYSCLASN----SAGDRS-RHFNLNVLVSPTIAGSGPEGSAEEVTVTLNSPTSLV-CEAQSYPPAIITWLKDGTPFESSRNVRV-----LPGGRTLQILNAKEEDAGRYTCVATNEAGETLKNYEVKVFVPPVINKNDIPGESLAPKEVKIKVN-----NTLTLECEAQAIPTPTLVW-YKDGQI------LKADGHLTITANGRIVQI--------------KHTQV--SDTGRYTCVATNIAGEDEKDFDVNIQVPPSFRGFGDSGPGNNGEVKDVILNNPISLYCETNAVPPPVLTWYK-DGHLLT-----------------SNDKVLILPGGRV--LQIPRAQVDDTGRYTCVAVNEAGEDSIQYDVRVLLPP----SIRGADGELPDEVTV 2869 HSP 9 Score: 78.1814 bits (191), Expect = 6.845e-14 Identity = 152/754 (20.16%), Postives = 274/754 (36.34%), Query Frame = 3 Query: 345 ISHESRLTIHNISSDNSGYYVC-RVTLLTTSEHIISLAVVTVKTPPKSISFHFNKSINVFQEQEFIAIQCSVSGGIPPPKISMYIVKDNAIKRLKIISSNFPNSTIAEVSAISLWRPHYLENRGFVMCTAINDAGVLTKNTSLLNIKYKPKI-KPFVPNTVNAMINQTIDLSCEVYANPAATIQW-------VIMQGLQIIDSSKFIAKIRPDMD--GPLICEAKNYLGSTKETVQLNVLRDPLIHID---SNYRVPKNSNYSINCRVTSNPPPEFIKWYKLSN--MTDSSAVLISDDAKLNFILIDRSSTGMYACVTQNIQISTTGKRKPANSEKTMFLTVTYKPKEPQILGNKIISIMKGEKFIIKCSTDRKSPGEPFPTLKWID-------VETKDIVSDMETFQVINSESRHNGKYKCLAENEIGKSFSRETALVTVNEAPSIITQHKNRKVFLSYSDLPQSIS--------FTCEFRGQPLYEARW---------------------------------RY--------GNEK--------IPPS------SQDFKIEDHRN--ISNERISQIFTKLTIDLYSRTFSQQTSLRSSPNG--------------RYNCEADNRHGIASLDY---FLXXXXXXXXXXNIRHRKIAASLNQNVVMIRCQAESISTMHIKWYKTNEHIVLPFQSKKYSIFEAEVTKYEPERDL-FTPGLKVNELTIKDLENDDFSNYSCVASNDQGIKKVNFEV 2288 +S L I ++G+Y C + + ++E SL V P +IS V + + ++C SG +P P ++ +K +SS + + + + + G C A+N G + L + P I V NTV ++ Q++ L C+ A P + W GL + + F+ I + G CEA N G T++ LNV P I S+ V + ++ C + PPP I W K + DS ++S +L +++ Y C+ + S K N + + +++ ++ + ++ +G ++C D G P P + W+ I+++ +++ ++ G+Y C+A N G++ + V V+ P+II Q + +P++IS TCE G P W RY G E+ +PPS +D K+++ +N ++ E ++T + + T L+ NG RY+C A N G S + L+ ++ +LN ++ C+A+S I W K + T +E R++ PG + L I + + +D Y+CVA+N+ G N+EV Sbjct: 1963 LSRGHVLEIDRAQVSDAGFYKCVAINVAGSTELTYSLQVYV----PPTISSKGGMVTVVVNDP--VRLECEASG-VPVPSLTW-------LKEGSPVSSFSDGIQVLSGGRVLSFISAQVSDAGHYTCVAVNAGGEQHREYEL-RVYVPPNIMGEEVNNTV--LMGQSVQLHCQSDAIPPPALSWRKDGRPLYRKPGLSVSEDGSFLKIISAQVQDTGRYTCEATNVAGKTEKHYNLNVWVPPSIRGSDEVSSLTVIEGGLITLVCESSGIPPPSLI-WKKDGSELKGDSRVRVLSGGRQLQISSAEKADASSYTCLASSAAGSAI---KEYNLQVYVRPSISSSAQDEE-------TVTRGGDITLRCEAD----GVPRPAVSWMKDGRPLSTGRKAQILNEGRLLRILEAQVADTGRYTCIAINVAGQADRKYD--VNVHVPPTIIGQ----------THMPENISVVVKNPVVLTCEASGMPPPAITWLKDGQPISTSSSVRVISGGRGLRLMHAASSDAGRYTCIVSNSAGEERKNFDLYVLVPPSIVNEGTVEDVKVKERQNAILACEVTGNPVPEITWLKDGQPLASDTRLQVMSNGRFLQISASQVADTGRYSCLASNSAGDRSRHFNLNVLVSPTIAGSGPEGSAEEVTVTLNSPTSLV-CEAQSYPPAIITWLK-------------------DGTPFESSRNVRVLPGGRT--LQILNAKEEDAGRYTCVATNEAGETLKNYEV 2650 HSP 10 Score: 75.8702 bits (185), Expect = 3.943e-13 Identity = 141/619 (22.78%), Postives = 225/619 (36.35%), Query Frame = 3 Query: 537 IAIQCSVSGGIPPPKISMYIVKDNAIKRLKIISSNFPNSTIAEVSAISLWRPHYLENRGFVMCTAINDAGVLTKNTSLLNIKYKPKIKPFVPNTVNAMINQTI------DLSCEVYANPAATIQW-------VIMQGLQIIDSSKFIAKIRPDMD--GPLICEAKNYLGSTKETVQLNVLRDPLIHIDSNY-RVPKNSNYSINCRVTSNPPPEFIKWYK----LSNMTDSSAVLISDDAKLNFILIDRSSTGMYACVTQNIQISTTGKRKPANSEKTMFLTVTYKPKEPQILGNKII-SIMKGEKFIIKCSTDRKSPGEPFPTLKWIDVETKD-----------IVSDMETFQVINSESRHNGKYKCLAENEIGKSFSRETALVTVNEAPSIITQHKNRKVFLSYSDLPQSISFTCEFRGQPLYEARWRYGNEKIPPSSQDFKIEDHRNISNERISQIFTKLTIDLYSRTFSQQTSLRSSPNGRYNCEADNRHGIASLDYFLXXXXXXXXXXNIRHRKIAASLNQNVVMIRCQAESISTMHIKWYKTNEHIVLPFQSKKYSIFEAEVTKYEPERDLFTPGLKVNE---LTIKDLENDDFSNYSCVASNDQGIKKVNFEV 2288 I++QC VSG IPPP S +KD + + + V I R LE+ G C A N AG ++ L ++ P I+ M+N+TI L C+ +P + W G+ I+ + R + G C A N GST+ T L V P I V N + C + P P + W K +S+ +D VL S L+FI S G Y CV N + + Y P P I+G ++ +++ G+ + C +D P P L W KD + D ++I+++ + G+Y C A N GK+ V V PSI + + + L I+ CE G P W+ ++ D ++ R +S R QI + D S Y C A + G A +Y L + P I + + + + +RC+A+ + + W K P + + +A++ +NE L I + + D Y+C+A N G ++V Sbjct: 1837 ISLQCVVSG-IPPP--STTWLKDG--RPVDTTQEFLKLESAGRVLHIKKAR---LEDAGKYTCVATNAAGEAQQHIRL-SVHEPPSIQ-----YAGEMLNETILAGFQIQLKCKATGSPLPAVTWYKDGRPLTSAAGVNILSRGHVLEIDRAQVSDAGFYKCVAINVAGSTELTYSLQVYVPPTISSKGGMVTVVVNDPVRLECEASGVPVPS-LTWLKEGSPVSSFSDGIQVL-SGGRVLSFISAQVSDAGHYTCVAVNA----------GGEQHREYELRVYVP--PNIMGEEVNNTVLMGQSVQLHCQSDAIPP----PALSW----RKDGRPLYRKPGLSVSEDGSFLKIISAQVQDTGRYTCEATNVAGKTEKHYNLNVWV--PPSIRGSDEVSSLTVIEGGL---ITLVCESSGIPPPSLIWKKDGSEL---KGDSRV---RVLSGGRQLQISSAEKADASS----------------YTCLASSAAGSAIKEYNLQVYVRPSISSSAQDEETVTRGGD--ITLRCEADGVPRPAVSWMKDGR----PLSTGR----KAQI---------------LNEGRLLRILEAQVADTGRYTCIAINVAGQADRKYDV 2367 HSP 11 Score: 75.485 bits (184), Expect = 5.663e-13 Identity = 134/634 (21.14%), Postives = 237/634 (37.38%), Query Frame = 3 Query: 327 SESQITISHESRLTIHNISSDNSGYYVCRVTLLTTSEHIISLAVVTVKTPPKSISFHFNKSINVFQEQEFIAIQCSVSGGIPPPKISMYIVKDNAIKRLKIISSNFPNSTIAEVSAISLWRPHYLENRGFVMCTAINDAGVLTKNTSLLNIKYKPKIKPFVPNTVNAMINQTIDLSCEVYANPAATIQWVIMQGLQIIDSSKFIAKIRPDMDGPL-------------ICEAKNYLG--STKETVQLNVLRDPLIHIDSNY-RVPKNSNYSINC-RVTSNPPPEFIKWYKLSNMTDSSAVLISDDAKLNFILIDRSSTGMYACVTQNIQISTTGKRKPANSEKTMFLTVTYKPKEPQILGNKIISIMKGEKFIIKCSTDRKSPGEPFPTLKW------IDVETKDI-VSDMETFQVINSESRHNGKYKCLAENEIGKSFSRETALVTVNEAPSIITQ---HKNRKVFLSYSDL-PQSISFTCEFRGQPLYEARWRYGNEKIPPSSQDFKIEDHRNISNERISQIFTKLTIDLYSRTFSQQTSLRSSPNGRYNCEADNRHGIASLDYFLXXXXXXXXXXNIRHRKIAASLNQNVVMIRCQAESISTMHIKWYKTNEHIVLPFQSKKYSIFEAEVT 2144 S+ ++ + L I N ++G Y C + + ++ A+V+ P+ H + I + Q+ ++C V+G +P P I M+ D +K ++S + T+ Y C A+N AG + L++ P+ P+ ++A I I L C +P + W + + + + MDG L +CEA+N+ G K V + L PLI + V ++ ++ C + NP PE + +T S V + D L+ + + G Y C+T+N+ +S +T L V P G +I S ++G + C ++ G P P + W +D+ +++ + + + +G++ C A N G S + V V S + + H N + L S + I+ CE P W + I P F+ I L S + + T R + +G Y C A N G S L + PP I R K+ + + + C + + + W K + VL S +Y I + +T Sbjct: 646 GSSRHRMTPDGTLIIKNTGLKDAGTYGCLASNVAGTDS--QTAIVSYIESPQVTVPHSDLLIGLGQK---TVMECRVTG-VPHPDI-MWYKGDLQLKPSSVLSMDPQRGTLTIQQTQDTHAGQY-------TCVAVNSAGS-AQGYITLDVGSAPQFTKK-PSDLSADIGTNITLPCYAQGHPKPQLSWRREDNIALFTQRHGPSTVTHRMDGGLFITNLWVEDEATYVCEAQNHFGRIQVKAKVTVTGLVSPLIALSPTVVSVIEDQQVTLPCVLLAGNPLPERHWLHDNGLVTSSPYVTVRRDGSLHIEQVSQQDGGQYTCLTENVV---------GSSNRTTILNVYVMPTIQH--GPQIFSTIEGTPISLPC----RAHGVPKPDITWSKRGELLDLSGSVFSLTEDGSLHIHSPSGEESGEFVCTATNAAGYSSRKVQLTVYVRPKLSGVGEADIHDNSEKLLEMSVIVGDDITLPCEVESVPPPIITWAKDKQLISP---------------------FSPRHIQLPSGSM-RITDTRVTDSGMYLCVATNIAGNFSQTVKLSVLVPPSISAGPRAMKVQIG---HAIDLPCVTQGVPEPSVSWLK--DGTVLQDGS-RYRISDGALT 1220 HSP 12 Score: 67.781 bits (164), Expect = 1.073e-10 Identity = 82/364 (22.53%), Postives = 138/364 (37.91%), Query Frame = 3 Query: 699 LENRGFVMCTAINDAGVLTKNTSLLNIKYKPKIKPFVPNTVNAMINQTIDLSCEVYANPAATIQWVIMQGLQIIDS--------SKFIAKIRPDMDGPLICEAKNYLGSTKETVQLNVLRDPLIHIDSNYRVPKNSNYS------INCRVTSNPPPEFIKWYKLSNMTDSSAVLISDDAKLNFILIDRSSTGMYACVTQNIQISTTGKRKPANSEKTMFLTVTYKPKEPQILGNKIISIMKGEKFIIKCSTDRKSPGEPFPTLKW----IDVETKDIVS---DMETFQVINSESRHNGKYKCLAENEIGKSFSRETALVTVNEAPSIITQHKNRKVFLSYSDLPQSISFTCEFRGQPLYEARWR 1727 L++ GF C AI+ AG T L + P I VP A + L+C V + + W +D S I ++ PD G C A N G + V LNV P++ +D P+N + I C P P + + + SS ++ D L G Y C+ N+ +T ++ P+ + +I + G+K +++C + G P P + W + ++ ++S T + ++ H G+Y C+A N G + T + V AP Q + LS +D+ +I+ C +G P + WR Sbjct: 485 LKDEGFYECIAISSAGTGRAQTFLDVSEPPPAIT--VPFNATASPGANVILTCLVTSTVRFNLTWQRGDVDARLDHRIRVTTNLSLEIQRVTPDDVGWYTCIAANEGGVSAARVYLNVQEPPVVTVD-----PRNQTFQTGQEIWIRCSAKGYPSPMVVWTHNDMFIMGSSRHRMTPDGTLIIKNTGLKDAGTYGCLASNVA---------GTDSQTAIVSYIESPQVTVPHSDLLIGL--GQKTVMEC----RVTGVPHPDIMWYKGDLQLKPSSVLSMDPQRGTLTIQQTQDTHAGQYTCVAVNSAGSAQGYIT--LDVGSAP----QFTKKPSDLS-ADIGTNITLPCYAQGHPKPQLSWR 819 HSP 13 Score: 62.7734 bits (151), Expect = 3.495e-9 Identity = 102/437 (23.34%), Postives = 178/437 (40.73%), Query Frame = 3 Query: 363 LTIHNISSDNSGYYVC-RVTLLTTSEHIISLAVVTVKTPP--KSISFHFNKSINVFQEQEFIAIQCSVSGGIPPPKISMYIVKDNAIKRLKIISSNFPNSTIAEVSAISLWRPHYLENRGFVMCTAINDAGVLTKNTSLLNIKYKPKIKPFVPN-TVNAMINQTIDLSCEVYANPAATIQW---------------VIMQGLQI-IDSSKFIAKIRPDMDGPLICEAKNYLGSTKETVQLNVLRDPLI---HIDSNYRVPKNSNYSINCRVTSNPPPEFIKWYKLSNMTDSS--AVLISDDAKLNFILIDRSSTGMYACVTQNIQISTTGKRKPANSEKTMFLTVTYKPKEPQIL----GNKIISIMKGEKFIIKCSTDRKSPGEPFPTLKWID-------VETKDIVSDMETFQVINSESRHNGKYKCLAENEIGK 1565 L + ++S ++G Y C V T+E L V PP + N S+ + Q + C V+G P P I+ Y KD ++++ S+ + I + +++ G +C AIN AG ++ L++ P I V + ++A++NQ I L C+V +P TIQW V+ +G Q+ I S++ + R C A N G + L++ P I ++ S V + ++ C V P P + WYK + SS A + L + S G Y C ++ +EK + L V Y P P I G + ++ + I++C + G P P+L W+ E+ ++ +++N+ G+Y C+A + G+ Sbjct: 1316 LILASVSPLDNGEYTCMAVNDAGTTEKKYQLKV---NVPPDIRDNGLLSNVSVVINQPTNLV---CDVTG-TPVPVITWY--KDG----VEVVPSS--DVQILQKGKTLKLLKAAVQDAGRYICKAINIAGSRERDF-YLDVLVPPTIIGTVGSRDLSAVLNQEIVLECKVKGDPFPTIQWYKDRKPVFLGDPNIEVLNRGQQLKIKSARLGDQAR------YQCSATNAAGKQSKDFNLSIFVPPSIKGGNVSSEVTVLLGNLVTLECEVRGVPLPA-VTWYKNGEVILSSRQAQYVDRGQFLKILRAQVSDAGQYTCRVTSVA---------GTAEKVVELDV-YVP--PSITAGSDGPTDMKVVLNKSLILECEAE----GHPPPSLTWLKDGSPVAVRESLRVLDQGRKIEILNALQSDAGRYVCVATSVAGE 1713
BLAST of hemicentin-1 isoform X2 vs. Ensembl Zebrafish
Match: hmcn1 (hemicentin 1 [Source:ZFIN;Acc:ZDB-GENE-041014-322]) HSP 1 Score: 110.153 bits (274), Expect = 1.561e-23 Identity = 157/688 (22.82%), Postives = 283/688 (41.13%), Query Frame = 3 Query: 327 SESQITISHESRLT-IHNISSDNSGYYVCRVTLLTTSEHIISLAVVTVKTPPKSISFHFNKSINVFQEQEFI-----AIQCSVSGGIPPPKISMYIVKDNAIKRLKIISSN-----FPNSTIAEVSAISLWRPHYLENRGFVMCTAINDAGVLTKNTSLLNIKYKPKIKPF---VPNTVNAMINQTIDLSCEVYANPAATIQWVI-MQGLQIIDSSKFIAKIRPDM--------DGPLICEAKNYLGSTKETVQLNVLRDPLIHI--DSNYRVPKNSNYSINCRVTSNPPPEFIKWYKLSNMTDSS--AVLISDDAKLNFILIDRSSTGMYACVTQNIQISTTGKRKPAN-SEKTMFLTVTYKPKEPQILGN--KIISIMKGEKFIIKCSTDRKSPGEPFPTLKWID-----VETKD--IVSDMETFQVINSESRHNGKYKCLAENEIG---KSFSRETALVTVNEAPSIITQHKNRKVFLSYSDLPQSISFTCEFRGQPLYEARWRYGNEKIPPSSQDFKIEDHRNISNERISQIFTKLTIDLYSRTFSQQTSLRS--SPNGRYNCEADNRHGIASLDYFLXXXXXXXXXXNIRHRKIAASLNQNVVMIRCQAESISTMHIKWYKTNEHIVLPFQSKKYSIFEAEVTKYEPERDLFTPGLKVNELTIKDLENDDFSNYSCVASNDQG 2264 ++ +TI+ R+ I + ++G Y C T + + V ++ PP F + N + ++ I ++ C + +PPP ++ Y K +++SN P + ++ + ++ G C A+N+AG + + + P I+ +P+ V ++N+T+ L C+V +P I WV Q L ++ + ++ R G +C A+N G+ +++ L+V P I + N V N+ S+NC T PPP ++W+K +S A+++ L + S G Y+CV N PA ++K ++LTV P G+ ++++ G+ +++C ++ P P + W ET + I++D + Q+ +E G+Y C A N G K+F + ++ P + + R V + ++F C+ G IPP S + + N R+ + L + + S Q S RS S +G Y C A N G A +Y L+I PP I + +++ LN +V ++ C+AE T I+W K I Q K P+ + LT+ + D Y+CVA+N G Sbjct: 2705 ADGHLTITANGRIVQIKHTQVSDTGRYTCVATNIAGEDE--KDFDVNIQVPPSFRGFGDSGPGNNGEVKDVILNNPISLYCETNA-VPPPVLTWY-------KDGHLLTSNDKVLILPGGRVLQIPRAQV------DDTGRYTCVAVNEAGEDSIQYDV-RVLLPPSIRGADGELPDEVTVLVNKTMLLECQVDGSPTPKISWVKDSQPLTQDNTHRLLSNGRTLQILNAQVTDTGRYVCVAQNLAGTAEKSFNLHVHVSPTIVGIREENVTVVLNNFVSLNCEATGLPPPT-LRWFKDRRPVQASTNALIMPGGRTLQILKAKMSDGGKYSCVAVN----------PAGEAQKLIYLTVYVPPSIRHNSGDLPVVLNVQVGKSVMLECESNAVPP----PVITWYKNGRPIAETANLRILADGQMLQLKETEVSDTGQYVCKATNVAGQVDKNFH-----LNIHVPPRLDGPAEERVV----ETISNPVTFACDATG--------------IPPPSLTW-------LKNGRVIENSESLEMHILSGGSKLQIS-RSQLSDSGTYTCVASNVEGKAQKNYHLVIHVPPNIIGSELPSEMSVLLNDSVQLV-CRAEGTPTPEIQWLKDGMTISRTAQKN---------IKISPDG---------STLTVTAVHTSDSGKYTCVATNQAG 3310 HSP 2 Score: 100.138 bits (248), Expect = 1.543e-20 Identity = 152/680 (22.35%), Postives = 251/680 (36.91%), Query Frame = 3 Query: 363 LTIHNISSDNSGYYVCRVTLLTTSEHIISLAVVTVKTPPKSISFHFNKSINVFQEQEFIAIQCSVSGGIPPPKISMYIVKDNAIKRLKII--SSNFPNSTIAEVSAISLWRPHYLENRGFVMCTAINDAGVLTKNTSLLNIKYKPKI-KPFVPNTVNAMINQTIDLSCEVYANPAATIQWVIMQGLQIIDSSKFIAKIRPDMD------------GPLICEAKNYLGSTKETVQLNVLRDPLIHIDSNYRVPK------NSNYSINCRVTSNPPPEFIKWYK--LSNMTDSSAVLISDDAKLNFILIDRSSTGMYACVTQNIQISTTGKRKPANSEKTMFLTVTYKPKEPQILGNKIISIMKGEKFIIKCSTDRKSPGEPFPTLKWIDVE---TKD----IVSDMETFQVINSESRHNGKYKCLAENEIGKSFSRETALVTVNEAPSIITQHKNRKVFLSYSDLPQSISFTCEFRGQPLYEARWRYGNEKIPPSSQDFKIEDHRNISNERISQIFTKLTIDLYSRTFSQQTSLRSSPNGRYNCEADNRHGIASLDYFLXXXXXXXXXXNIRHRKIAASLNQNVVMIRCQAESISTMHIKWYKTNEHIVLPFQSKKYSIFEAEVTKYEPERDLFTPG--LKVNELTIKDLENDDFSNYSCVASNDQGIKKVNFEVVFKSQP 2306 L + ++G YVC+ T + + + + PP+ + + + C +G IPPP ++ +K ++I S + ++ S + + R L + G C A N G KN L+ I P I +P+ ++ ++N ++ L C P IQW + G+ I +++ KI PD G C A N G LNV PLI N K +S+ +I C + +PPP+ + W K L S L+S L S G Y CV N + + L V P + ++++KG C D G P P + W+ +KD +++ T Q++N H G+Y C A N+ G + SR +L V + P I +V + + + + CE G PL W +P + NI R Q+ R S Q GRY C A + G + FL+ + P R + + L V + C+++++ + W K + + K P + + G L++N + D + YSCVASN G + +F++ P Sbjct: 3099 LQLKETEVSDTGQYVCKAT--NVAGQVDKNFHLNIHVPPRLDGPAEERVVETISNP--VTFACDATG-IPPPSLTW-------LKNGRVIENSESLEMHILSGGSKLQISRSQ-LSDSGTYTCVASNVEGKAQKNYHLV-IHVPPNIIGSELPSEMSVLLNDSVQLVCRAEGTPTPEIQW-LKDGMTISRTAQKNIKISPDGSTLTVTAVHTSDSGKYTCVATNQAGEEDRIFNLNVYVPPLIQ--GNGPAAKELTTVLDSSINIECVASGSPPPQ-LNWLKNGLPLPVSSQIRLLSAGQVLRIARAQVSDGGSYTCVASN---------RAGVDNRHYTLQVYVPPSLDGAGSTEEVTVVKGSTASFICIAD----GTPSPVIIWLRTGASVSKDAHISLLNQNSTMQIVNVLVNHTGRYTCTAHNQAGDA-SRHFSL-KVLDPPRINGSGVPAEVSVVVNHV---LELLCEADGIPLPTLTWLKDGRPLPQT---------ENIRLLRDGQML---------RVASAQV----ENTGRYTCLASSPAGDDDKE-FLVRVHVPPNIAGDRGVQDVSVLQNRQVTLECKSDAVPPPTLTWLKDDAPL-----------------KMSPRVRVLSSGRYLQINNAVL-----GDGAQYSCVASNVAGETRRHFKLSVNVPP 3697 HSP 3 Score: 93.5893 bits (231), Expect = 1.536e-18 Identity = 152/708 (21.47%), Postives = 265/708 (37.43%), Query Frame = 3 Query: 318 VPDSESQITISHESRLTIHNISSDNSGYYVCRVTLLTTSEHIISLAVVTVKTPPKSISFHFNKSINVFQEQEFIAIQCSVSGGIPPPKISMYIVKDNAIK---RLKIISSN----FPNSTIAEVSAISLWRPHYLENRGFVMCTAINDAGVLTKNTSLLNIKYKPKIKPFVPNTVNAMINQTIDLSCEVYANPAATIQWVIMQGLQII----------DSSKFIAKIRPDMDGPLICEAKNYLGSTKETVQLNVLRDPLI-HIDSNYRVPKNSNYSINCRVTSNPPPEFIKWYK----LSNMTDSSAVLISDDAKLNFILIDRSSTGMYACVTQNIQISTTGKRKPANSEKTMFLTVTYKPKEPQILGNKIISIMKGEKFIIKCSTDRKSPGEPFPTLKWIDVETKD---IVSDMETFQVINS--------ESRHNGKYKCLAENEIGKSFSRETALVTVNEAPSIITQHKNRKVFLSYSDLPQSISFTCEFRGQPLYEARWRYGNEKIPPSSQDFKIEDHRNISNERISQIFTKLTIDLYSRTFSQQTSLRSSPNGRYNCEADNRHGIASLDYFLXXXXXXXXXXNIRHRKIAASLNQNVVMIRCQAESISTMHIKWYKTNEHIVLPFQSKKYSIFEAEVTKYEPERDLFTPGLKVNELTIKDLENDDFSNYSCVASNDQGIKKVNFEVVFKSQPDPPYDLRVTDFE 2342 +P +E+ + L + + +N+G Y C + + L V V PP + ++V Q ++ + ++C S +PPP ++ ++ D +K R++++SS N+ + + + S C A N AG T+ L++ P IK P +V+ INQ + L C V PA I W QG + D S I + G +C A N G+ ++ V L V P I +N V N +++C T P P + W K L+ + + + L I T +Y CV N + + + LTV P ++S + +I C+ G P P L W +KD + D E F ++ S + H+G+Y C+A+N G + R L TV+E+P I + V L+ ++ C G P W+ I + F + + + Q + + +G Y C A N G A L ++ PP+I +IR +A ++ V ++C +E T + W+K + + + + S ++ +P D Y+C +N G ++ + + P +RV + E Sbjct: 3553 LPQTENIRLLRDGQMLRVASAQVENTGRYTCLASSPAGDDDKEFL--VRVHVPPNIAGDRGVQDVSVLQNRQ-VTLECK-SDAVPPPTLT-WLKDDAPLKMSPRVRVLSSGRYLQINNAVLGDGAQYS--------------CVASNVAGE-TRRHFKLSVNVPPTIKDG-PQSVSVHINQPVVLECVVNGVPAPRITWR-KQGSILAGNNPRYKFGEDGSLRILSAQVTDTGRYLCMATNQAGTERKRVDLQVYVPPSIAEGPTNITVTVNVQTTLSCEATGIPKPS-VSWTKNTQALNTDQNQNMYRLLSSGSLVVIAPSVEDTALYECVVSN---------EAGQESRAIQLTVHVPPSIADEATELVVSRLS--PVVIGCTAS----GVPHPVLYW----SKDGLRLAKDGEGFTILPSGPLEITAADLSHSGRYSCVAKNAAGTAH-RHVQL-TVHESPVIQSHPSTLDVILN-----NHVTLPCRATGSPRPTITWQKEGINIFTTGGGFTVLPNGGL----------------------QISKAKVEDSGTYMCVAQNPAGTALGKTKLRVQVPPVITSDIRAYTVALDVS---VTLQCNSEGFPTPSVSWHKDGQLLSESVRQRVLSTGALQIAFAQP---------------------GDTGRYTCTVANVAGSSSLDISLTVQIPP----SIRVGESE 4161 HSP 4 Score: 88.1965 bits (217), Expect = 6.978e-17 Identity = 151/635 (23.78%), Postives = 247/635 (38.90%), Query Frame = 3 Query: 327 SESQITISHESRLTIHNISSDNSGYYVCRVTLLTTSEHIISLAVVTVKTPPKSISFHFNKSINVFQEQ---------EFIAIQCSVSGGIPPPKISMYIVKDNAIKRLKIISSNFPNSTIAEVSAISLWRPHYLENRGFVMCTAINDAGVLTKNTSLLNIKYKPKIKPFVPNTVNAMINQTIDLSCEVYANPAATIQW-----VIMQG--LQIIDSSKFIAKIRPDMDGPLICEAKNYLGSTKETVQLNVLRDPLIHI-DSNYRVP-----KNSNYSINCRVTSNPPPEFIKWYKLSN--MTDSSAVLISDDAKLNFILIDRS--STGMYACVTQNIQISTTGKRKPANSEKTMFLTVTYKP--KEPQILGNKIISIMKGEKFIIKCSTDRKSPGEPFPTLKWID-----VETKD--IVSDMETFQVINSESRHNGKYKCLAENEIGKSFSRETAL-VTVNEAPSIITQHKNRKVFLSYSDLPQSISFTCEFRGQPLYEARWRYGNEKIPPSSQDFKIEDHRNISNERISQIFTKLTIDLYSRTFSQQTSLRSSPNG---RYNCEADNRHGIASLDYFLXXXXXXXXXXNIRHRKIAASLNQNVVMIRCQAESISTMHIKWYKTNEHIVLPFQSK 2114 S S +++ + L IH+ S + SG +VC T + + +TV PK +S I+ E+ + I + C V +PPP I+ KD K + S F I S + + G +C A N AG ++ T L++ P I P + I IDL C P ++ W V+ G +I D + + ++ +G +C A N G + +QL+V P++ + + + P N + C P P IKW++ + + V I +D L IL S G Y C+ N +EK L V P ++ +L N + I + + + G P P + W V + D I+ +T +++ + + G+Y C A N G SRE + V P+II +R + + L Q I C+ +G P +W +K +R I++ +R QQ ++S+ G RY C A N G S D+ L I PP IK ++ L N+V + C+ + + WYK E I+ Q++ Sbjct: 1015 SGSVFSLTEDGSLHIHSPSGEESGEFVCTAT--NAAGYSSRKVQLTVYVRPK-LSGVGEADIHDNSEKLLEMSVIVGDDITLPCEVES-VPPPIITW--AKD------KQLISPFSPRHIQLPSGSMRITDTRVTDSGMYLCVATNIAGNFSQ-TVKLSVLVPPSISAG-PRAMKVQIGHAIDLPCVTQGVPEPSVSWLKDGTVLQDGSRYRISDGALTLNQVALTDEGIYVCRAVNIAGKEETAIQLHVQVPPVVEVSEPPFNSPLQERVANQQIAFPCPAKGTPEP-VIKWFRNGHELTGNEPGVSILEDGTL-LILASVSPLDNGEYTCMAVN---------DAGTTEKKYQLKVNVPPDIRDNGLLSNVSVVINQPTNLVCDVT------GTPVPVITWYKDGVEVVPSSDVQILQKGKTLKLLKAAVQDAGRYICKAINIAG---SRERDFYLDVLVPPTIIGTVGSRDL---SAVLNQEIVLECKVKGDPFPTIQW-------------YK---------DRKPVFLGDPNIEVLNR--GQQLKIKSARLGDQARYQCSATNAAGKQSKDFNLSIFVPPSIKGGNVSSEVTVLLG-NLVTLECEVRGVPLPAVTWYKNGEVILSSRQAQ 1587 HSP 5 Score: 88.1965 bits (217), Expect = 7.339e-17 Identity = 155/692 (22.40%), Postives = 270/692 (39.02%), Query Frame = 3 Query: 330 ESQITISHESRLTIHNISSDNSGYYVCRVTLLTTSEHIISLAVVTVKTPPKSISFHFNKSINVFQEQEFIAIQCSVSGGIPPPKISMYIVKDNA-IKRLKI--ISSNFPNSTI--AEVSAISLWRPHYLENRGFVMCTAINDAGVLTKNTSLLNIKYKPKIKPFVPNTVNAMINQTIDLSCEVYANPAATIQWVIMQGLQIIDSSKF-----------IAKIRPDMDGPLICEAKNYLGSTKETVQLNVLRDPLIHIDS---NYRVPKNSNYSINCRVTSNPPPEFIKWYKLSNMTDSSAVLISDDAKLNFILIDR---SSTGMYACVTQNIQISTTGKRKPANSEKTMFLTVTYKPKEPQILGNKIISIMKGEKFIIKCSTDRKSPGEPFPTLKWIDVETK--------DIVSDMETFQVINSESRHNGKYKCLAENEIGKSFSRETALVTVNEAPSIITQHKNRKVFLSYSDLPQSISFTCEFRGQPLYEARWRYGNEKIPPSSQDFKIEDHRNISNERISQIFTKLTIDLY-SRTFSQQTSLRSSPNGRYNCEADNRHGIASLDYFLXXXXXXXXXXNIRHRKIAASLN---QNVVMIRCQAESISTMHIKWYKTNEHIVLPFQSKKYSIFEAEVTKYEPERDLFTPGLKVNELTIKDLENDDFSNYSCVASNDQG--IKKVNFEVVFK 2297 ES + ++ I N ++G YVC T + + I V+V PP V + ++C +G P P I+ +KD +K + I+SN I A+VS +L+ C A N+AG + + ++ P I+ P + +++ +I L C V P + W + G + + +F I K R + G C A N G ++ ++L+V P I N + + C+ T +P P + WYK +SA ++ ++ + + IDR S G Y CV N+ ST E T L V P G +++++ + ++C ++ G P P+L W+ + ++S I+++ G Y C+A N G+ RE L V P+I+ + N V + QS+ C+ ++ IPP + ++ +D R ++ K + + +F + S + GRY CEA N G Y L + PP +IR +SL ++ + C++ I + W K + K + + + G +L I E D S+Y+C+AS+ G IK+ N +V + Sbjct: 1678 ESLRVLDQGRKIEILNALQSDAGRYVCVATSVAGEKEI--KYDVSVLVPPVVDGASDTTDATVILNN-ILELECYATG-RPTPTITW--LKDGVPVKHGEGVRITSNGRRLVISRAQVSDTALFH-----------CVATNEAGEQEREFKV-SVHVPPAIRSTGPAERSVVLHTSISLQCVVSGIPPPSTTW-LKDGRPVDTTQEFLKLESAGRVLHIKKARLEDAGKYTCVATNAAGEAQQHIRLSVHEPPSIQYAGEMLNETILAGFQIQLKCKATGSPLPA-VTWYK-DGRPLTSAAGVNILSRGHVLEIDRAQVSDAGFYKCVAINVAGST---------ELTYSLQVYVPPTISSKGG--MVTVVVNDPVRLEC----EASGVPVPSLTWLKEGSPVSSFSDGIQVLSGGRVLSFISAQVSDAGHYTCVAVNAGGEQH-REYEL-RVYVPPNIMGEEVNNTVLMG-----QSVQLHCQ--------------SDAIPPPALSWR-KDGR--------PLYRKPGLSVSEDGSFLKIISAQVQDTGRYTCEATNVAGKTEKHYNLNVWVPP----SIRGSDEVSSLTVIEGGLITLVCESSGIPPPSLIWKKDGSEL-----------------KGDSRVRVLSGG---RQLQISSAEKADASSYTCLASSAAGSAIKEYNLQVYVR 2279 HSP 6 Score: 85.8853 bits (211), Expect = 3.576e-16 Identity = 154/700 (22.00%), Postives = 254/700 (36.29%), Query Frame = 3 Query: 363 LTIHNISSDNSGYYVCRVTLLTTSEHIISLAVVTVKT----------------PPKSISFHFNKSINVFQEQEFIAIQCSVSGGIPPPKISMYIVKDNAIKRLKIISSNFPNSTIAEVSAISLWRPHYLENRGFVMCTAINDAGVLTKNTSLLNIKYKPKIKPFVPN-------TVNAMINQTIDLSCEVYANPAATIQW-------------VIMQGLQIIDSSKFIAKIRPDMDGPLICEAKNYLGSTKETVQLNVLRDPLIHIDSNYRVPK------NSNYSINCRVTSNPPPEFIKWYKLSN--MTDSSAVLISDDAKLNFILIDRSSTGMYACVTQNIQISTTGKRKPANSEKTMFLTVTYKPKEPQILGNKIISIMKGEKFIIKCSTDRKSPGEPFPTLKW------IDVETKD-IVSDMETFQVINSESRHNGKYKCLAENEIGKSFSRETALVTVNEAPSIITQHKNRKVFLSYSDLPQSISFTCEFRGQPLYEARWRYGNEKIPPSSQDFKIEDHRNISNERISQIFTKLTIDLYSRTFSQQTSLRSSPNGRYNCEADNRHGIASLDYFLXXXXXXXXXXNIRHRKIAASLNQNVVMIRCQAESISTMHIKWYKTNEHIVLPFQSKKYSIFEAEVTKYEPERDLFTPGLKVNELTIKDLENDDFSNYSCVASNDQGIKKVNFEVVFKSQPD 2309 L I N +++G Y C + T+E +L VK PK + N ++ + E + IP P + Y KD I + + N I ++ + + G C A N AG K+ + NI+ P + F + + ++N I L CE A P + W +I+ G +++ I + + D G C A N G + VL P I ++ +P N + C+V +P P+ I W K S D++ L+S+ L + + TG Y CV QN+ +EK+ L V P I + ++ F+ S + ++ G P PTL+W + T I+ T Q++ ++ GKY C+A N G++ ++ +TV PSI + V L+ + +S+ CE P W Y N + + + +I L Q S G+Y C+A N G ++ L I PP + R + N V C A I + W K N ++ +S + I ++L I + D Y+CVASN +G + N+ +V P+ Sbjct: 2619 LQILNAKEEDAGRYTC----VATNEAGETLKNYEVKVFVPPVINKNDIPGESLAPKEVKIKVNNTLTLECEAQ----------AIPTPTLVWY--KDGQILKADGHLTITANGRIVQIKHTQV------SDTGRYTCVATNIAGEDEKDFDV-NIQVPPSFRGFGDSGPGNNGEVKDVILNNPISLYCETNAVPPPVLTWYKDGHLLTSNDKVLILPGGRVLQ----IPRAQVDDTGRYTCVAVNEAGEDSIQYDVRVLLPPSIR-GADGELPDEVTVLVNKTMLLECQVDGSPTPK-ISWVKDSQPLTQDNTHRLLSNGRTLQILNAQVTDTGRYVCVAQNLA---------GTAEKSFNLHVHVSPTIVGIREENVTVVLN--NFV---SLNCEATGLPPPTLRWFKDRRPVQASTNALIMPGGRTLQILKAKMSDGGKYSCVAVNPAGEA--QKLIYLTVYVPPSIRHNSGDLPVVLNV-QVGKSVMLECESNAVPPPVITW-YKNGRPIAETANLRI---------------------LADGQMLQLKETEVSDTGQYVCKATNVAGQVDKNFHLNIHVPPRLDGPAEERVVETI--SNPVTFACDATGIPPPSLTWLK-NGRVIENSESLEMHILSGG-----------------SKLQISRSQLSDSGTYTCVASNVEGKAQKNYHLVIHVPPN 3230 HSP 7 Score: 82.0333 bits (201), Expect = 4.665e-15 Identity = 150/670 (22.39%), Postives = 262/670 (39.10%), Query Frame = 3 Query: 381 SSDNSGYYVCRVTLLTTSEHIISLAV-VTVKTPPKSISFHFNKSINVFQEQEFIAIQCSVSGGIPPPKISMYIVKDNAIKRLKIISSNF---PNSTIAEVSAISLWRPHYLENRGFVMCTAINDAGVLTKNTSLLNIKYKPKIKPFVPNTVNAMINQTIDLSCEVYANPAATIQW--------VIMQGLQIIDSSKF-IAKIRPDMDGPLICEAKNYLGSTKETVQLNVLRDPLIHID-SNYRVPKNSNYSINCRVTSNPPPEFIKWYKLSN-MTDSSAVLISDDAKLNFILIDRSSTGMYACVTQNIQISTTGKRKPANSEKTMFLTVTYKPKEPQILGNKIISIMKGEKFIIKCSTDRKSPGEPFPTLKW--IDVETKDIVSD---METFQVI--NSESRHNGKYKCLAENEIGKSFSRETALVTVNEAPSI------ITQHKNRKVFLSYSDLPQSISFTCEFRGQPLYEARWRYGNEKIPPSSQDFKIEDHRNISNERISQIFTKLTIDLYSRTFSQQTSLRSSPNGRYNCEADNRHG-IASLDYFLXXXXXXXXXXNIRHRKIAASLNQNVVMIRCQAESISTMHIKWYKTNEHIVLPFQSKKYSIFEAEVTKYEPERDLFTPGLKVNELTIKDLENDDFSNYSCVASNDQGIKKVNFEVVFKSQ 2303 S +++ Y C V+ E S A+ +TV PP S + V + I C+ SG +P P +Y KD RL F P+ + E++A L + G C A N AG ++ L + P I+ P+T++ ++N + L C +P TI W G ++ + I+K + + G +C A+N G+ +L V P+I D Y V + + ++ C P P + W+K +++S + L TG Y C N+ +S + LTV P +G +S+++ + ++ C D G P PT+ W D+ D ++ + T ++ ++ +G Y C+ N +G+ SR +L +++ P+ + +K ++ + C G P + W + N +P DH N +E L I+ S+ S G Y C A+N G I SL F+ +K PPII ++ +I L N ++ C+ I+W K ++ + + ++ L L I ++D NY CVA+ND G+ + + +S+ Sbjct: 3851 SVEDTALYECVVSNEAGQE---SRAIQLTVHVPP---SIADEATELVVSRLSPVVIGCTASG-VPHP--VLYWSKDGL--RLAKDGEGFTILPSGPL-EITAADL------SHSGRYSCVAKNAAGTAHRHVQL-TVHESPVIQSH-PSTLDVILNNHVTLPCRATGSPRPTITWQKEGINIFTTGGGFTVLPNGGLQISKAKVEDSGTYMCVAQNPAGTALGKTKLRVQVPPVITSDIRAYTVALDVSVTLQCNSEGFPTPS-VSWHKDGQLLSESVRQRVLSTGALQIAFAQPGDTGRYTCTVANVA---------GSSSLDISLTVQIPPS--IRVGESEVSVVENTQALLTCVAD----GVPQPTITWEKDDIPLTDTTAEYTILPTGDLLIDTAQPEDSGSYTCVGTNSMGQD-SRTISL-SIHTHPAFTELLGDVALNKRERLLM-----------VCGVTGIPPPKITWTFNNNIVPAQY------DHYNGHSE--------LVIERVSKDDS----------GTYTCMAENSVGSIKSLG-FVYVKEPPIIDGDVHSNRIEP-LGGNAIL-NCEVRGDPLPTIQWSKKGINVQISNRIRQ---------------------LDNGSLAIYG-TSEDAGNYMCVATNDAGVVERTVTLTLQSK 4422 HSP 8 Score: 80.8777 bits (198), Expect = 1.208e-14 Identity = 138/647 (21.33%), Postives = 245/647 (37.87%), Query Frame = 3 Query: 537 IAIQCSVSGGIPPPKISMYIVKDNAIKRLKIISSNFPNSTIAEVSAISLWRPHYLENRGFVMCTAINDAGVLTKNTSLLNIKYKPKI--KPFVPNTVNAMINQTIDLSCEVYANPAATIQWVIMQGLQIIDSSKFIAKIRPDMD-----------GPLICEAKNYLGSTKETVQLNVLRDPLIHIDS---NYRVPKNSNYSINCRVTSNPPPEFIKWYKLSN--MTDSSAVLISDDAKLNFILIDRSSTGMYACVTQNIQISTTGKRKPANSEKTMFLTVTYKPKEPQILGNKIISIMKGEKFIIKCSTDRKSP--------GEPFPTLKWIDVETKDIVSDMETFQVINSESRHNGKYKCLAENEIGKSFSRETALVTV------NEAPSIITQHKNRKVFLSYSDLPQSISFTCEFRGQPLYEARWRYGNEKIPPSSQDFKIEDHRNI-SNERISQIFTKLTIDLYSRTFSQQTSLRSSPNGRYNCEADNRHGIASLDYFLXXXX-----XXXXXXNIRHRKIAASLNQNVVMIRCQAESISTMHIKWYKTNEHIVLPFQSKKYSIFEAEVTKYEPERDLFTPGLKVNELTIKDLENDDFSNYSCVASNDQGIKKVNFEVVFKSQPDPPYDLRVTDFEW-DSVTI 2360 I ++C G +P P +S +K + +S+ + E + + + + G C AIN AG + + N+ P I + +P ++ ++ + L+CE P I W ++ Q I +S + I G C N G ++ L VL P I + + +V + N + C VT NP PE I W K +D+ ++S+ L + TG Y+C+ N + G R + + ++ T P+ ++ + ++ C P G PF + + + V + T Q++N++ G+Y C+A NE G++ V V N+ P K K+ ++ +++ CE + P W Y + +I K + H I +N RI QI + T + S GRY C A N G D+ + I+ + ++ + N + + C+ ++ + WYK + H++ ++ L PG +V L I + DD Y+CVA N+ G + ++V P +R D E D VT+ Sbjct: 2298 ITLRCEADG-VPRPAVSW-------MKDGRPLSTGRKAQILNEGRLLRILEAQ-VADTGRYTCIAINVAGQADRKYDV-NVHVPPTIIGQTHMPENISVVVKNPVVLTCEASGMPPPAITW--LKDGQPISTSSSVRVISGGRGLRLMHAASSDAGRYTCIVSNSAGEERKNFDLYVLVPPSIVNEGTVEDVKVKERQNAILACEVTGNPVPE-ITWLKDGQPLASDTRLQVMSNGRFLQISASQVADTGRYSCLASN----SAGDRS-RHFNLNVLVSPTIAGSGPEGSAEEVTVTLNSPTSLV-CEAQSYPPAIITWLKDGTPFESSRNVRV-----LPGGRTLQILNAKEEDAGRYTCVATNEAGETLKNYEVKVFVPPVINKNDIPGESLAPKEVKIKVN-----NTLTLECEAQAIPTPTLVW-YKDGQI------LKADGHLTITANGRIVQI--------------KHTQV--SDTGRYTCVATNIAGEDEKDFDVNIQVPPSFRGFGDSGPGNNGEVKDVILNNPISLYCETNAVPPPVLTWYK-DGHLLT-----------------SNDKVLILPGGRV--LQIPRAQVDDTGRYTCVAVNEAGEDSIQYDVRVLLPP----SIRGADGELPDEVTV 2868 HSP 9 Score: 78.1814 bits (191), Expect = 7.199e-14 Identity = 152/754 (20.16%), Postives = 274/754 (36.34%), Query Frame = 3 Query: 345 ISHESRLTIHNISSDNSGYYVC-RVTLLTTSEHIISLAVVTVKTPPKSISFHFNKSINVFQEQEFIAIQCSVSGGIPPPKISMYIVKDNAIKRLKIISSNFPNSTIAEVSAISLWRPHYLENRGFVMCTAINDAGVLTKNTSLLNIKYKPKI-KPFVPNTVNAMINQTIDLSCEVYANPAATIQW-------VIMQGLQIIDSSKFIAKIRPDMD--GPLICEAKNYLGSTKETVQLNVLRDPLIHID---SNYRVPKNSNYSINCRVTSNPPPEFIKWYKLSN--MTDSSAVLISDDAKLNFILIDRSSTGMYACVTQNIQISTTGKRKPANSEKTMFLTVTYKPKEPQILGNKIISIMKGEKFIIKCSTDRKSPGEPFPTLKWID-------VETKDIVSDMETFQVINSESRHNGKYKCLAENEIGKSFSRETALVTVNEAPSIITQHKNRKVFLSYSDLPQSIS--------FTCEFRGQPLYEARW---------------------------------RY--------GNEK--------IPPS------SQDFKIEDHRN--ISNERISQIFTKLTIDLYSRTFSQQTSLRSSPNG--------------RYNCEADNRHGIASLDY---FLXXXXXXXXXXNIRHRKIAASLNQNVVMIRCQAESISTMHIKWYKTNEHIVLPFQSKKYSIFEAEVTKYEPERDL-FTPGLKVNELTIKDLENDDFSNYSCVASNDQGIKKVNFEV 2288 +S L I ++G+Y C + + ++E SL V P +IS V + + ++C SG +P P ++ +K +SS + + + + + G C A+N G + L + P I V NTV ++ Q++ L C+ A P + W GL + + F+ I + G CEA N G T++ LNV P I S+ V + ++ C + PPP I W K + DS ++S +L +++ Y C+ + S K N + + +++ ++ + ++ +G ++C D G P P + W+ I+++ +++ ++ G+Y C+A N G++ + V V+ P+II Q + +P++IS TCE G P W RY G E+ +PPS +D K+++ +N ++ E ++T + + T L+ NG RY+C A N G S + L+ ++ +LN ++ C+A+S I W K + T +E R++ PG + L I + + +D Y+CVA+N+ G N+EV Sbjct: 1962 LSRGHVLEIDRAQVSDAGFYKCVAINVAGSTELTYSLQVYV----PPTISSKGGMVTVVVNDP--VRLECEASG-VPVPSLTW-------LKEGSPVSSFSDGIQVLSGGRVLSFISAQVSDAGHYTCVAVNAGGEQHREYEL-RVYVPPNIMGEEVNNTV--LMGQSVQLHCQSDAIPPPALSWRKDGRPLYRKPGLSVSEDGSFLKIISAQVQDTGRYTCEATNVAGKTEKHYNLNVWVPPSIRGSDEVSSLTVIEGGLITLVCESSGIPPPSLI-WKKDGSELKGDSRVRVLSGGRQLQISSAEKADASSYTCLASSAAGSAI---KEYNLQVYVRPSISSSAQDEE-------TVTRGGDITLRCEAD----GVPRPAVSWMKDGRPLSTGRKAQILNEGRLLRILEAQVADTGRYTCIAINVAGQADRKYD--VNVHVPPTIIGQ----------THMPENISVVVKNPVVLTCEASGMPPPAITWLKDGQPISTSSSVRVISGGRGLRLMHAASSDAGRYTCIVSNSAGEERKNFDLYVLVPPSIVNEGTVEDVKVKERQNAILACEVTGNPVPEITWLKDGQPLASDTRLQVMSNGRFLQISASQVADTGRYSCLASNSAGDRSRHFNLNVLVSPTIAGSGPEGSAEEVTVTLNSPTSLV-CEAQSYPPAIITWLK-------------------DGTPFESSRNVRVLPGGRT--LQILNAKEEDAGRYTCVATNEAGETLKNYEV 2649 HSP 10 Score: 75.8702 bits (185), Expect = 4.078e-13 Identity = 141/619 (22.78%), Postives = 225/619 (36.35%), Query Frame = 3 Query: 537 IAIQCSVSGGIPPPKISMYIVKDNAIKRLKIISSNFPNSTIAEVSAISLWRPHYLENRGFVMCTAINDAGVLTKNTSLLNIKYKPKIKPFVPNTVNAMINQTI------DLSCEVYANPAATIQW-------VIMQGLQIIDSSKFIAKIRPDMD--GPLICEAKNYLGSTKETVQLNVLRDPLIHIDSNY-RVPKNSNYSINCRVTSNPPPEFIKWYK----LSNMTDSSAVLISDDAKLNFILIDRSSTGMYACVTQNIQISTTGKRKPANSEKTMFLTVTYKPKEPQILGNKII-SIMKGEKFIIKCSTDRKSPGEPFPTLKWIDVETKD-----------IVSDMETFQVINSESRHNGKYKCLAENEIGKSFSRETALVTVNEAPSIITQHKNRKVFLSYSDLPQSISFTCEFRGQPLYEARWRYGNEKIPPSSQDFKIEDHRNISNERISQIFTKLTIDLYSRTFSQQTSLRSSPNGRYNCEADNRHGIASLDYFLXXXXXXXXXXNIRHRKIAASLNQNVVMIRCQAESISTMHIKWYKTNEHIVLPFQSKKYSIFEAEVTKYEPERDLFTPGLKVNE---LTIKDLENDDFSNYSCVASNDQGIKKVNFEV 2288 I++QC VSG IPPP S +KD + + + V I R LE+ G C A N AG ++ L ++ P I+ M+N+TI L C+ +P + W G+ I+ + R + G C A N GST+ T L V P I V N + C + P P + W K +S+ +D VL S L+FI S G Y CV N + + Y P P I+G ++ +++ G+ + C +D P P L W KD + D ++I+++ + G+Y C A N GK+ V V PSI + + + L I+ CE G P W+ ++ D ++ R +S R QI + D S Y C A + G A +Y L + P I + + + + +RC+A+ + + W K P + + +A++ +NE L I + + D Y+C+A N G ++V Sbjct: 1836 ISLQCVVSG-IPPP--STTWLKDG--RPVDTTQEFLKLESAGRVLHIKKAR---LEDAGKYTCVATNAAGEAQQHIRL-SVHEPPSIQ-----YAGEMLNETILAGFQIQLKCKATGSPLPAVTWYKDGRPLTSAAGVNILSRGHVLEIDRAQVSDAGFYKCVAINVAGSTELTYSLQVYVPPTISSKGGMVTVVVNDPVRLECEASGVPVPS-LTWLKEGSPVSSFSDGIQVL-SGGRVLSFISAQVSDAGHYTCVAVNA----------GGEQHREYELRVYVP--PNIMGEEVNNTVLMGQSVQLHCQSDAIPP----PALSW----RKDGRPLYRKPGLSVSEDGSFLKIISAQVQDTGRYTCEATNVAGKTEKHYNLNVWV--PPSIRGSDEVSSLTVIEGGL---ITLVCESSGIPPPSLIWKKDGSEL---KGDSRV---RVLSGGRQLQISSAEKADASS----------------YTCLASSAAGSAIKEYNLQVYVRPSISSSAQDEETVTRGGD--ITLRCEADGVPRPAVSWMKDGR----PLSTGR----KAQI---------------LNEGRLLRILEAQVADTGRYTCIAINVAGQADRKYDV 2366 HSP 11 Score: 75.0998 bits (183), Expect = 6.109e-13 Identity = 134/634 (21.14%), Postives = 237/634 (37.38%), Query Frame = 3 Query: 327 SESQITISHESRLTIHNISSDNSGYYVCRVTLLTTSEHIISLAVVTVKTPPKSISFHFNKSINVFQEQEFIAIQCSVSGGIPPPKISMYIVKDNAIKRLKIISSNFPNSTIAEVSAISLWRPHYLENRGFVMCTAINDAGVLTKNTSLLNIKYKPKIKPFVPNTVNAMINQTIDLSCEVYANPAATIQWVIMQGLQIIDSSKFIAKIRPDMDGPL-------------ICEAKNYLG--STKETVQLNVLRDPLIHIDSNY-RVPKNSNYSINC-RVTSNPPPEFIKWYKLSNMTDSSAVLISDDAKLNFILIDRSSTGMYACVTQNIQISTTGKRKPANSEKTMFLTVTYKPKEPQILGNKIISIMKGEKFIIKCSTDRKSPGEPFPTLKW------IDVETKDI-VSDMETFQVINSESRHNGKYKCLAENEIGKSFSRETALVTVNEAPSIITQ---HKNRKVFLSYSDL-PQSISFTCEFRGQPLYEARWRYGNEKIPPSSQDFKIEDHRNISNERISQIFTKLTIDLYSRTFSQQTSLRSSPNGRYNCEADNRHGIASLDYFLXXXXXXXXXXNIRHRKIAASLNQNVVMIRCQAESISTMHIKWYKTNEHIVLPFQSKKYSIFEAEVT 2144 S+ ++ + L I N ++G Y C + + ++ A+V+ P+ H + I + Q+ ++C V+G +P P I M+ D +K ++S + T+ Y C A+N AG + L++ P+ P+ ++A I I L C +P + W + + + + MDG L +CEA+N+ G K V + L PLI + V ++ ++ C + NP PE + +T S V + D L+ + + G Y C+T+N+ +S +T L V P G +I S ++G + C ++ G P P + W +D+ +++ + + + +G++ C A N G S + V V S + + H N + L S + I+ CE P W + I P F+ I L S + + T R + +G Y C A N G S L + PP I R K+ + + + C + + + W K + VL S +Y I + +T Sbjct: 645 GSSRHRMTPDGTLIIKNTGLKDAGTYGCLASNVAGTDS--QTAIVSYIESPQVTVPHSDLLIGLGQK---TVMECRVTG-VPHPDI-MWYKGDLQLKPSSVLSMDPQRGTLTIQQTQDTHAGQY-------TCVAVNSAGS-AQGYITLDVGSAPQFTKK-PSDLSADIGTNITLPCYAQGHPKPQLSWRREDNIALFTQRHGPSTVTHRMDGGLFITNLWVEDEATYVCEAQNHFGRIQVKAKVTVTGLVSPLIALSPTVVSVIEDQQVTLPCVLLAGNPLPERHWLHDNGLVTSSPYVTVRRDGSLHIEQVSQQDGGQYTCLTENVV---------GSSNRTTILNVYVMPTIQH--GPQIFSTIEGTPISLPC----RAHGVPKPDITWSKRGELLDLSGSVFSLTEDGSLHIHSPSGEESGEFVCTATNAAGYSSRKVQLTVYVRPKLSGVGEADIHDNSEKLLEMSVIVGDDITLPCEVESVPPPIITWAKDKQLISP---------------------FSPRHIQLPSGSM-RITDTRVTDSGMYLCVATNIAGNFSQTVKLSVLVPPSISAGPRAMKVQIG---HAIDLPCVTQGVPEPSVSWLK--DGTVLQDGS-RYRISDGALT 1219 HSP 12 Score: 67.781 bits (164), Expect = 1.100e-10 Identity = 82/364 (22.53%), Postives = 138/364 (37.91%), Query Frame = 3 Query: 699 LENRGFVMCTAINDAGVLTKNTSLLNIKYKPKIKPFVPNTVNAMINQTIDLSCEVYANPAATIQWVIMQGLQIIDS--------SKFIAKIRPDMDGPLICEAKNYLGSTKETVQLNVLRDPLIHIDSNYRVPKNSNYS------INCRVTSNPPPEFIKWYKLSNMTDSSAVLISDDAKLNFILIDRSSTGMYACVTQNIQISTTGKRKPANSEKTMFLTVTYKPKEPQILGNKIISIMKGEKFIIKCSTDRKSPGEPFPTLKW----IDVETKDIVS---DMETFQVINSESRHNGKYKCLAENEIGKSFSRETALVTVNEAPSIITQHKNRKVFLSYSDLPQSISFTCEFRGQPLYEARWR 1727 L++ GF C AI+ AG T L + P I VP A + L+C V + + W +D S I ++ PD G C A N G + V LNV P++ +D P+N + I C P P + + + SS ++ D L G Y C+ N+ +T ++ P+ + +I + G+K +++C + G P P + W + ++ ++S T + ++ H G+Y C+A N G + T + V AP Q + LS +D+ +I+ C +G P + WR Sbjct: 484 LKDEGFYECIAISSAGTGRAQTFLDVSEPPPAIT--VPFNATASPGANVILTCLVTSTVRFNLTWQRGDVDARLDHRIRVTTNLSLEIQRVTPDDVGWYTCIAANEGGVSAARVYLNVQEPPVVTVD-----PRNQTFQTGQEIWIRCSAKGYPSPMVVWTHNDMFIMGSSRHRMTPDGTLIIKNTGLKDAGTYGCLASNVA---------GTDSQTAIVSYIESPQVTVPHSDLLIGL--GQKTVMEC----RVTGVPHPDIMWYKGDLQLKPSSVLSMDPQRGTLTIQQTQDTHAGQYTCVAVNSAGSAQGYIT--LDVGSAP----QFTKKPSDLS-ADIGTNITLPCYAQGHPKPQLSWR 818 HSP 13 Score: 62.7734 bits (151), Expect = 3.645e-9 Identity = 76/322 (23.60%), Postives = 133/322 (41.30%), Query Frame = 3 Query: 699 LENRGFVMCTAINDAGVLTKNTSLLNIKYKPKIKPFVPN-TVNAMINQTIDLSCEVYANPAATIQW---------------VIMQGLQI-IDSSKFIAKIRPDMDGPLICEAKNYLGSTKETVQLNVLRDPLI---HIDSNYRVPKNSNYSINCRVTSNPPPEFIKWYKLSNMTDSS--AVLISDDAKLNFILIDRSSTGMYACVTQNIQISTTGKRKPANSEKTMFLTVTYKPKEPQIL----GNKIISIMKGEKFIIKCSTDRKSPGEPFPTLKWID-------VETKDIVSDMETFQVINSESRHNGKYKCLAENEIGK 1565 +++ G +C AIN AG ++ L++ P I V + ++A++NQ I L C+V +P TIQW V+ +G Q+ I S++ + R C A N G + L++ P I ++ S V + ++ C V P P + WYK + SS A + L + S G Y C ++ +EK + L V Y P P I G + ++ + I++C + G P P+L W+ E+ ++ +++N+ G+Y C+A + G+ Sbjct: 1415 VQDAGRYICKAINIAGSRERDF-YLDVLVPPTIIGTVGSRDLSAVLNQEIVLECKVKGDPFPTIQWYKDRKPVFLGDPNIEVLNRGQQLKIKSARLGDQAR------YQCSATNAAGKQSKDFNLSIFVPPSIKGGNVSSEVTVLLGNLVTLECEVRGVPLPA-VTWYKNGEVILSSRQAQYVDRGQFLKILRAQVSDAGQYTCRVTSVA---------GTAEKVVELDV-YVP--PSITAGSDGPTDMKVVLNKSLILECEAE----GHPPPSLTWLKDGSPVAVRESLRVLDQGRKIEILNALQSDAGRYVCVATSVAGE 1712
BLAST of hemicentin-1 isoform X2 vs. Ensembl Zebrafish
Match: hmcn2 (hemicentin 2 [Source:ZFIN;Acc:ZDB-GENE-030131-9765]) HSP 1 Score: 100.138 bits (248), Expect = 1.402e-20 Identity = 117/485 (24.12%), Postives = 186/485 (38.35%), Query Frame = 3 Query: 723 CTAINDAGVLTKNTSL---LNIKYKPKIKPFVPNTVNAMINQTIDLSCEVYANPAATIQWVIMQGLQII-DSSKFIAKIRPDMDGPLICEAKNYLGSTKETVQLNVLRDPLIHIDSNYRVPK--NSNYSINCRVTSNPPPEFIKWYK----LSNMTDSSAVLISDDAKLNFILIDRSSTGMYACVTQNIQISTTGKRK------PANSEKTMFLTVTYKPKEPQILGNKIISIMKGEKFIIKCSTDRKSPGEPFPTLKWIDVETKDIVSDMET-----------FQVINSESRHNGKYKCLAENEIGKSFSRETALVTVNEAPSIITQHKNRKVFLSYSDLPQSISFTCEFRGQPLYEARWRYGNEKIPPSSQDFKIEDHRNISNERISQIFTKLTIDLYSRTFSQQTSLRSSPNGRYNCEADNRHGIASLDYFLXXXXXXXXXXNIRHRKIAASLNQNVVMIRCQAESISTMHIKWYKTNEHIV 2096 C+A+N AG N SL L ++ KP+I P P+T+ A+I QT+ L C V P+ + W + GL + D I ++ G C A+N G + L+VL P + + NS I C +P P+ ++W+K + V +++D L S +G + CV N S K + P + L +T K+P LG I P PT+ W TKD +ET ++ + H G++ C A+N G++ T V +AP +I+ + + Q + C G+PL W + E + P+ D +E R+ S+R G Y C A N G + + L I+ P+I+ + ++ L V+ C+ E I I W K N+ IV Sbjct: 1142 CSAVNPAG----NVSLTYNLQVQAKPRIHP-APSTLKALIGQTVVLPCVVQGEPSPQVSW-LHNGLPVASDRMLKIQAVQHSDSGTYRCVARNSAGEDTIQIVLDVLEGPYFETNGETVIESVANSKVLIPCPARGSPAPQ-VRWFKNGLEVHMERSEHGVSLAEDGALVIGSASASHSGDFKCVATNEAGSVERKTRLKVNVPPEIQDDGQLLNLTVTLKQPLTLGCDAFGI-------------------PTPTISW----TKDNRPVLETPGVYLQNGKRLLKIYRVQHDHAGRFSCTAQNSAGEAKREYTIEV---QAPPVISGTSGVQEVTIMAG--QEVDMQCRVSGRPLPSVEWTHDGEVLSPNG-DPHVEFLEKGQVLRVK-------------------SVRPRDRGLYQCVATNNAGTQTRQFRLTIQAAPLIRDSGEDSEVTVVLGFPAVL-HCEVEGIPLPTITWLKDNQPIV 1570 HSP 2 Score: 83.1889 bits (204), Expect = 2.405e-15 Identity = 106/433 (24.48%), Postives = 178/433 (41.11%), Query Frame = 3 Query: 711 GFVMCTAINDAGVLTKNTSLLNIKYKPKIKPFVPNTVNAMINQTIDLSCEVYANPAATIQWVIMQGLQIIDSSKF---------IAKIRPDMDGPLICEAKNYLGSTKETVQLNVLRDPLIHIDS-NYRVPKNSNYSINCRVTSNPPPEFIKWYKLSN-MTDSSAVLISDDAKLNFILIDRSSTGMYACVTQNIQISTTGKRKPANSEKTMFLTVTYKPKEPQI-LGNKIISIMKGEKFIIKCSTDRKSPGEPFPTLKWIDVETKDI-VSDM-------ETFQVI--NSESRHNGKYKCLAENEIGKSFSRETALVTVN------EAPSIITQHKNRKVFLSYSDLPQSISFTCEFRGQPLYEARWRYGNEKIPPSSQDFKIEDHRNISNERISQIFTKLTIDLYSRTFSQQTSLRSSPNGRYNCEADNRHGI 1925 G C+A N GV K+ +L ++ P+I+P + V +++ ++ L CEV P TI W +G+ + + +++ G C A+N G+ QL + P++ + Y V S++C P PE + W++ + DSS + + + L+ R G+Y C +N + G+ A+ + + L + P PQI +G IS+M+G + ++ C+ + G P P + W E K + VS+M E+ +I +E+ G + C+A N G +R +TVN E P +T +K QS+S +C G P W N +S D R S IF +T+ S G Y C A+N G+ Sbjct: 2922 GKYTCSARNPVGVAYKHVTL-TVQEPPEIRP-MAEEVQVVLHHSVVLPCEVQGFPRPTITWQ-REGVPVATGHRLAVLSNGALKFSRVTLGDAGTYQCLAQNEAGTALAQTQLILQVPPVLSVPRLEYVVVLGQPVSLDCVADGQPKPE-VTWHRDRRPVVDSSHLRLFSNGSLHITATQRGDAGIYTCSARN----SVGR---ASHDVRLIL---HTP--PQIFVGQSEISVMQGLRVMLPCA----AQGVPEPRMSW---EKKGVSVSNMPGKFTLRESGGLIIERAEAGDAGLFTCVATNTAGS--ARWDIRLTVNMRPAFKELPGDVTLNKG-----------QSLSLSCHAEGTPTPTITWTANNRPYTGASVD---------ETGRSSVIFDNVTV---------------SDGGTYACIAENTVGL 3294 HSP 3 Score: 81.6481 bits (200), Expect = 5.776e-15 Identity = 146/698 (20.92%), Postives = 255/698 (36.53%), Query Frame = 3 Query: 315 VVPDSESQITISHE-SRLTIHNISSDNSGYYVCRVTLLTTSEHIISLAVVTVKTPPKSISFHFNKSINVFQEQE-FIAIQCSVSGGIPPPKISMYIVKDN----AIKRLKIISSNFPNSTIAEVSAISLWRPHYLENRGFVMCTAINDAGVLTKNTSLLNIKYKPKIKPFVPNTVNAMIN-QTIDLSCEVYANPAATIQW------VIMQGLQIIDSSK---FIAKIRPDMDGPLICEAKNYLGSTKETVQLNVLRDPLIH---IDSNYRVPKNSNYSINCRVTSNPPPEFIKWYKLSN-MTDSSAVLISDDAKLNFILIDRSSTGMYACVTQNIQISTTGKRKPANSEKTMFLTVTYKPKEPQILGN---KIISIMKGEKFIIKCSTDRKSPGEPFPTLKWIDVETK-------DIVSDMETFQVINSESRHNGKYKCLAENEIGKS---FSRETALVTV-NEAPSIITQHKNRKVFLSYSDLPQSISFTCEFRGQPLYEARWRYGNEKIPPSSQDFKIEDHRNISNERISQIFTKLTIDLYSRTFSQQTSLRSSPNGRYNCEADNRHGIASLDYFLXXXXXXXXXXNIRHRKIAASLNQNVVMIRCQAESISTMHIKWYKTNEHIVLPFQSKKYSIFEAEVTKYEPERDLFTPGLKVNELTIKDLENDDFSNYSCVASNDQGIKKVNFEVVFKSQP 2306 +V + I IS + S LT ++ ++SG Y C E I V P SIS + V Q + ++C G P P+IS ++D R++++S++ ST+ IS P +L + G C A + AG+ N L ++ P ++ P A++ ++ L+CE P T+ W + + ++D + ++ + P G C A N GS+ +T L VL P I + +S + C T PPP + W K + D+ A++ D L + G+Y C+ + PA + P P +LG+ + +S+ ++C TD P P ++W K ++ + ++ + +G+Y C+ N G + F+ E L V E S+I H + Q CE G P WR +P + N R + L S + ++++ S GRY C N+ G S + +K + + Q V+ C++ I + W + I + QS Y + + L I +D + C +N+ G ++ EV+ + P Sbjct: 2248 LVNGNTEHINISPDGSTLTFLSVKPEDSGTYTCLAVSSAGQETKIYTLFALV---PPSISGETSVPREVHTTQHSVVTLECKAKG-TPQPQISW--LRDGHPLLLSPRIRLLSAD---STLR----IS---PVHLSDSGIYTCVARSRAGLAELNFDL-QVQAPPAVERTEPTEQVAVVQGSSVTLTCEARGVPPPTLSWLKDGQPLSLHRNLLLDGQETRFLLSDVGPSDAGLYSCVASNQAGSSTKTFNLTVLEPPKITGSLSPEEQLIAVDSLLELECIATGLPPPT-LSWLKDGRPIQDNMAIIERDGQLLRINKVQVEDAGLYTCLASS----------PAGEDGRNHWVRVQLP--PTLLGSNDIRTVSVPAKGHLTLECQTDSDPP----PEIEWYKDNVKVQLGGRIQSIASGQFLEIQDVRMHDSGQYSCVVTNIAGSTSLFFTVEILLPPVIREGSSLIIAH-----------VGQDAVLPCEVEGAPSSSVMWRKDGGPVP-------------LHNNRFT---------LLSEGSLRISTVQLSDVGRYYCSVSNQAG--SDHRGMDLKVYVGPSISPGPFNVTVVTGQRAVL-SCESTGIPAPQVSWRRNGSPISVD-QSSAYRLMSS------------------GSLVITSPTAEDEGYFECTVTNEVGEERRVIEVILQVPP 2856 HSP 4 Score: 81.2629 bits (199), Expect = 8.159e-15 Identity = 119/555 (21.44%), Postives = 211/555 (38.02%), Query Frame = 3 Query: 723 CTAINDAGVLTKNTSLLNIKYKPKIKPFVPNTVNAMINQTIDLSCEVYANPAATIQWV-------IMQGLQIIDSSKFIAKIRPDMD--GPLICEAKNYLGSTKETVQLNVLRDPLI----HIDSNYRVP-KNSNYSINCRVTSNPPPEFIKWYKLSNMTDSSAVLISDDAKLNFILIDRSSTGMYACVTQNIQISTTGKRKPANSEKTMFLTVTYKPKEPQILGNKIISIMKGEKFIIKCSTDRKSPGEPFPTLKWIDVETKDIVSDMETFQVINSESR------------HNGKYKCLAENEIGKSFSRETALVTVNEAPSIITQHKNRKVFLSYSDLPQSISFTCEFRGQPLYEARW-RYGNEKIPPSSQDFKIEDHRNISNERISQIFTKLTIDLYSRTFSQQTSLRSSPNGRYNCEADNRHGIASLDYFLXXXXXXXXXXNIRHRKIAASLNQNVVMIRCQAESISTMHIKWYKTNEHIVLPFQSKKYSIFEAEVTKYEPERDLFTPGLKVNELTIKDLENDDFSNYSCVASNDQGIKKVNFEVVFKSQP 2306 C A N AG + + SL +I+ P+I ++ + I L C+V A P A I W G+ I+ + + R G +C A N G ++++ L + P + +S R P S + C P PE + WY+ + L + +L + + + G+Y C NI ++T +TV P L + + G + C ++ G P P + W+ KD S +E+ N +R H G Y C+A+N G++ ++ +T+ PSII +V + + + ++ C G P + W R G + +++ H NIS + + F S++ +G Y C A + G + Y L PP I + + +VV + C+A+ I W + ++L S + + A+ T L I + D Y+CVA + G+ ++NF++ ++ P Sbjct: 1908 CVAENKAGAVERLYSL-SIQVPPRIVGRREEEMSVVEGHMISLLCDVQAYPPADIIWTKDGQMLEFTTGIHILPGGQMLQIPRAGQQDAGQYVCTATNSAGQDQKSILLTIYALPALVPRLESESEVRTPLVGSTLILRCEANGIPKPE-VTWYRNGLQLAAGNGLRIERQQLEIVGVQVADGGVYTCKVSNIA---------GQVDRTFRVTVHVPPVMEGPLHETLTQNL-GSHITLIC----EASGIPVPNIAWL----KD-GSPIESSLQWNWSTRANRLELGPLQLSHAGTYTCIAKNTEGQT--QKDYSLTIYAPPSIIDSGHPSEV---SAPVGEELALECRAMGSPAPKVSWLRNGKTLVNGNTE------HINISPDGSTLTFL---------------SVKPEDSGTYTCLAVSSAGQETKIYTLFALVPPSISGETSVPREVHTTQHSVVTLECKAKGTPQPQISWLRDGHPLLL---SPRIRLLSADST-----------------LRISPVHLSDSGIYTCVARSRAGLAELNFDLQVQAPP 2395 HSP 5 Score: 73.559 bits (179), Expect = 2.014e-12 Identity = 106/523 (20.27%), Postives = 198/523 (37.86%), Query Frame = 3 Query: 828 MINQTIDLSCEVYANPAATIQWVIMQGLQIIDSSKF----------IAKIRPDMDGPLICEAKNYLGSTKETVQLNVLRDPLIHIDSNYRVPK-----NSNYSINCRVTSNPPPEFIKWYK--LSNMTDSSAVLISDDAKLNFILIDRSSTGMYACVTQNIQISTTGKRKPANSEKTMFLTVTYKPKEPQILGNK--IISIMKGEKFIIKCSTDRKSPGEPFPTLKWIDVETKD-----------IVSDMETFQVINSESRHNGKYKCLAENEIGKSFSRETALVTVNEAPSIITQHKNRKVFLSYSDLPQSISFTCEFRGQPLYEARWRYGNEKIPPSSQDFKIEDHRNISNERISQIFTKLTIDLYSRTFSQQTSLRSSPNGRYNCEADNRHGIASLDYFLXXXXXXXXXXNIRHRKIAASLNQNVVMIRCQAESISTMHIKWYKTNEHIVLPFQSKKYSIFEAEVTKYEPERDLFTPGLKVNELTIKDLENDDFSNYSCVASNDQGIKKVNFEVVFKSQP 2306 ++ +I LSCE A P + W QG Q+ S I +++ + G C+A N G K L VL P+I ++ + NS S+ C V+ +P P + W K L +DS ++ D L + + S Y CV +N K E+ L++ P+ I+G + +S+++G + C P + + W TKD I+ + Q+ + + G+Y C A N G+ +++ L+T+ P+++ + ++ + + ++ CE G P E W Y N + +IE R + ++ + G Y C+ N G + + + PP+++ + H + +L ++ +I C+A I +I W K I Q + + N L + L+ Y+C+A N +G + ++ + + P Sbjct: 1755 LLGHSISLSCESNAIPPPRLSWY-RQGRQLTSSDGVVLAPGGHILQIPRVQLEDAGKYTCQAVNEAGEDKMHYDLEVLVPPVISGQTDEFMQDVDTVVNSTVSLRCDVSGHPSPS-VSWIKDGLPLYSDSRHNILEDGKLLEIVNVQVSDGASYQCVAEN---------KAGAVERLYSLSIQVPPR---IVGRREEEMSVVEGHMISLLCDVQAYPPAD----IIW----TKDGQMLEFTTGIHILPGGQMLQIPRAGQQDAGQYVCTATNSAGQ--DQKSILLTIYALPALVPRLESESE-VRTPLVGSTLILRCEANGIPKPEVTW-YRNGLQLAAGNGLRIE-----------------------RQQLEIVGVQVADGGVYTCKVSNIAGQVDRTFRVTVHVPPVMEGPL-HETLTQNLGSHITLI-CEASGIPVPNIAWLKDGSPIESSLQ--------------------WNWSTRANRLELGPLQLSHAGTYTCIAKNTEGQTQKDYSLTIYAPP 2206 HSP 6 Score: 70.4774 bits (171), Expect = 1.626e-11 Identity = 145/674 (21.51%), Postives = 231/674 (34.27%), Query Frame = 3 Query: 336 QITISHESRLTIHNISSDNSGYYVCRVTLLTTSEHIISLAVVTVKTPPKSISFHFNKSINVFQEQEFIAIQCSVSGGIPPPKISMYIVKDNAIKRLKIISSNFPNSTIAEVSAISLWRPHYLENRGFVMCTAINDAGVLTKNTSLLNIKYKPKIKPFVPNTVNAMINQTIDLSCEVYANPAATIQWVIMQGLQIIDSSKF-------------IAKIRPDMDGPLICEAKNYLGSTKETVQLNV--LRDPLI-----HIDSNYRVPKNSNYSINCRVTSNPP-PEFIKWYKLSNMTDSSAVLISDDAKLNFILIDRS---STGMYACVTQNIQISTTGKRKPANSEKTMFLTVTYKPKEPQILGNKIISIMKGEKFIIKCSTDRKSPGEPFPTLKWI---DVETKDIVSDME----TFQVINSESRHNGKYKCLAENEIGKSFSRETALVTVNEAPSIITQHKNRKVFLSYSDLPQSISFTCEFRGQPLYEARWRYGNEKIPPSSQDFKIEDHRNISNERISQIFTKLTIDLYSRTFSQQTSLRSSPNGRYNCEADNRHGIASLDYFLXXXXXXXXXXNIRHRKIAASLNQNVVMIRCQAESISTMHIKWYKTNEHIVLPFQSKKYSIFEAEVTKYEPERDLFTPGLKVNELTIKDLENDDFSNYSCVASNDQG 2264 +++IS LTI + ++SG Y C L T S +V P SIS + V E +++C SG P I + D + + T+ L + G C A N AG + +L + P P + A + I L C P ++ W G I S I + D +G +CEAKN GS K ++ V L PL+ I + P N + CR+ P PE I + + V + D L+ +DR+ G Y C N+ S +TVT + P + + E I S + + G P PT+ W D + + + E + + + G Y C A + +G + SRE L+ VN P I+ ++ +++ + CE +G P W + IPP + F + ++ + + +KL Y C A N G SL Y L + + + + A + Q VV+ C + + + W H LP S + L I+ +++ D Y CVA N G Sbjct: 652 RMSISESGMLTIRGAAPEDSGNYTC---LATNEVGTASQSVNVNYAEPPSISVVQQMVMVVAGEDA--SLECQASG--TPSPIVKWQKGDLDLGTAPFAEQDVHRGTLQIRGVQEL-------DSGDYTCVASNIAGS-SSAVVVLQVGAAPTFSE-SPVDITASVGDNITLPCIARGFPTPSLIWRRQDGRPIFGKSSGHVGTSQLPSGALQIQSVWVDDEGVYLCEAKNQFGSIKALARVTVTGLEPPLLVQGAPSITTMIAQPLN----LPCRLLDGIPLPERIWTHNGKQVRVGGRVFLRSDGSLH---VDRAVPEDAGTYVCTAVNVAGSAN-------------ITVTVEVHAPPDIKAGPLHYTASEGTPISLSCEAR--GVPKPTISWSKGRDPLNRPVSAPFEAADGSLYISSPTEEDAGVYICTATSAVGYT-SREMHLI-VNSKPRIVGADGSQVTVKMAAEVGSEVILPCEVQGSPTPLVTWSRNGQTIPPVTAWFTMLPSGSLKISDVRVVDSKL----------------------YTCSAVNPAGNVSLTYNL--QVQAKPRIHPAPSTLKALIGQTVVL-PCVVQGEPSPQVSWL----HNGLPVASDRM-------------------------LKIQAVQHSDSGTYRCVARNSAG 1231 HSP 7 Score: 68.5514 bits (166), Expect = 6.201e-11 Identity = 114/548 (20.80%), Postives = 206/548 (37.59%), Query Frame = 3 Query: 537 IAIQCSVSGGIPPPKISMYIVKDNAIKRLKIISSNFPNSTIAEVSAISLWRPHYLENRGFVMCTAINDAGVLTKNTSLLNIKYKPKIK----PFVPNTVNAMINQTIDLSCEVYANPAATIQWVIMQGLQIIDSSKF----------IAKIRPDMDGPLICEAKNYLGSTKETVQLNVLRDPLI--HIDSNYRVPKNSNYSINCRVTSNPPPEFIKWYKLSNMTD--SSAVLISDDAKLNFILIDRSSTGMYACVTQNIQISTTGKRKPANSEKTMFLTVTYKPK-EPQILG-NKIISIMKGEKFIIKCSTDRKSPGEPFPTLKWID-----VETKDIVSDMETFQVINSESRHNGKYKCLAEN---EIGKSFSRETALVTVNEAPSIITQHKNRKVFLSYSDLPQSISFTCEFRGQPLYEARWRYGNEKIPPSSQDFKIEDHRNISNERISQIFTKLTIDLYSRTFSQQTSLRSSPNGRYNCEADNRHGIASLDYFLXXXXXXXXXXNIRHRKIAASLNQNVVMIRCQAESISTMHIKWYKTNEHIV 2096 I++ C S IPPP++S Y ++ + P I ++ + L E+ G C A+N+AG K L + P I F+ + V+ ++N T+ L C+V +P+ ++ W I GL + S+ I ++ C A+N G+ + L++ P I + V + S+ C V + PP + I W K M + + ++ L + G Y C N +K++ LT+ P P++ +++ + + G I++C + G P P + W + + + +++ + G Y C N ++ ++F + V E P T +N L I+ CE G P+ W I S Q N S R +++ + L+ S G Y C A N G DY L I PP I + +++A + + + + C+A + W + + +V Sbjct: 1760 ISLSCE-SNAIPPPRLSWYRQGRQLTSSDGVVLA--PGGHILQIPRVQL------EDAGKYTCQAVNEAGE-DKMHYDLEVLVPPVISGQTDEFMQD-VDTVVNSTVSLRCDVSGHPSPSVSW-IKDGLPLYSDSRHNILEDGKLLEIVNVQVSDGASYQCVAENKAGAVERLYSLSIQVPPRIVGRREEEMSVVEGHMISLLCDVQAYPPADII-WTKDGQMLEFTTGIHILPGGQMLQIPRAGQQDAGQYVCTATN---------SAGQDQKSILLTIYALPALVPRLESESEVRTPLVGSTLILRCEAN----GIPKPEVTWYRNGLQLAAGNGLRIERQQLEIVGVQVADGGVYTCKVSNIAGQVDRTFRVTVHVPPVMEGPLHETLTQN---------LGSHITLICEASGIPVPNIAWLKDGSPIESSLQ-------WNWST-RANRL--------------ELGPLQLSHAGTYTCIAKNTEGQTQKDYSLTIYAPPSIIDSGHPSEVSAPVGEELAL-ECRAMGSPAPKVSWLRNGKTLV 2249 HSP 8 Score: 61.6178 bits (148), Expect = 6.976e-9 Identity = 112/519 (21.58%), Postives = 185/519 (35.65%), Query Frame = 3 Query: 363 LTIHNISSDNSGYYVCRVTLLTTSEHIISLAVVTVKTPPKSISFHFNKSINVFQEQEFIAIQCSVSGGIPPPKISMY----IVKDNAIKRLKIISSNFPNSTIAEVSAISLWRPHYLENRGFVMCTAINDAGVLTKNTSLLNIKYKPKIKPFVPNT-VNAMINQTIDLSCEVYANPAATIQWV-----IMQGLQII----DSSKFIAKIRPDMDGPLICEAKNYLGSTKETVQLNVLRDPLIHIDSNY--------RVPKNSNYSINCRVTSNPPPEFIKWYK---------LSNMTDSSAVLISDDAKLNFILIDRSSTGMYACVTQN------------IQIS-------------TTGKRKPANSEKTMFLTVTYKPKEPQILGNKIISIMKGEKFIIKCSTDRKSPGEPFPTLKWIDVETKDIVSD-------METFQVINSESRHNGKYKCLAENEIGKSFSRETALVTVNEAPSIITQHKNRKVFLSYSD--LPQSISFTCEFRGQPLYEARW 1724 L I+ + D++G + C T ++ + V+ PP + + + QE + +QC VSG P P + ++ N ++ + +V + RP +RG C A N+AG T+ L I+ P I+ ++ V ++ L CEV P TI W+ I+ Q+ S +A R + G C A N G+ L ++ P I DS +V N +++C P P +W+K S ++ +S +L D+A L S G Y CV N IQ+ T G+R+ + P P + + ++ G + C ++ P P L W + SD Q+ + GKY C A NE G+ V V P +I+ + F+ D + ++S C+ G P W Sbjct: 1396 LKIYRVQHDHAGRFSC--TAQNSAGEAKREYTIEVQAPPVISGTSGVQEVTIMAGQE-VDMQCRVSGR-PLPSVEWTHDGEVLSPNGDPHVEFLEK-------GQVLRVKSVRP---RDRGLYQCVATNNAGTQTRQFR-LTIQAAPLIRDSGEDSEVTVVLGFPAVLHCEVEGIPLPTITWLKDNQPIVSSPQLTYTQGGQSLRVAAARGEDAGAYTCRATNPAGTAHRHYTLRIMVPPQIEGDSTILSFGRREEKVRINGTLTLSCLAKGFPEP-VTQWFKDGQLLNGNTHSGLSVNSHMLHVDNAML-------SHEGQYTCVVSNSAGEDKRDFHLTIQVPPVFHRVINGAADFTLGEREGDEED----------PDSPDGMVER-REVLLGHSISLSCESNAIPP----PRLSWYRQGRQLTSSDGVVLAPGGHILQIPRVQLEDAGKYTCQAVNEAGEDKMHYDLEVLV---PPVISGQTDE--FMQDVDTVVNSTVSLRCDVSGHPSPSVSW 1871 HSP 9 Score: 60.8474 bits (146), Expect = 1.206e-8 Identity = 111/547 (20.29%), Postives = 203/547 (37.11%), Query Frame = 3 Query: 363 LTIHNISSDNSGYYVCRVTLLTTSEHIISLAVVTVKTPPKSISFHFNKSINVFQEQEFIAIQCSVSGGIPPPKISMYIVKDNAIKRLKIISSNFPNSTIAEVSAISLWRPHYLENRGFVMCTAINDAGVLTKNTSL---LNIKYKPKIKPFVPNTVNAMINQTIDLSCEVYANPAATIQWVIMQGLQIIDSSKF---------IAKIRPDMDGPLICEAKNYLGSTKETVQLNVLRDPLIHIDS-NYRVPKNSNYSINCRVTSNPPPEFIKWYKLSN---MTDSSAVLISDDAKLNFILIDRSSTGMYACVTQNIQISTTGKRKPANSEKTMFLTVTYKPKEPQILGNKIISI--MKGEKFIIKCSTDRKSPGEPFPTL----KWIDVETKD---IVSDMETFQVINSESRHNGKYKCLAENEIGKSFSRETALVTVNEAPSIITQHKNRKVFLSYSDLPQSISFTCEFRGQPLYEARWRYGNEKIPPSSQDFKIEDHRNISNERISQIFTKLTIDLYSRTFSQQTSLRSSPNGRYNCEADNRHGIA 1928 L I+ + +++G Y C + + V V+ PP + + ++++V + + ++C PPP+I Y KDN +L + + E+ + + + G C N AG +TSL + I P I+ + + A + Q L CEV P++++ W G + +++F I+ ++ G C N GS + L V P I N V ++C T P P+ + W + + + SSA + L G + C N E+ + + + P ++ + + S+ +K ++ C + G P P + W+ + + V +++ + H GKY C A N +G ++ T +TV E P I + +V L + S+ CE +G P W+ E +P ++ HR + F+++T+ G Y C A N G A Sbjct: 2544 LRINKVQVEDAGLYTCLASSPAGEDG--RNHWVRVQLPPTLLGSNDIRTVSV-PAKGHLTLECQTDSD-PPPEIEWY--KDNVKVQLGGRIQSIASGQFLEIQDVRM------HDSGQYSCVVTNIAG----STSLFFTVEILLPPVIREG-SSLIIAHVGQDAVLPCEVEGAPSSSVMWRKDGGPVPLHNNRFTLLSEGSLRISTVQLSDVGRYYCSVSNQAGSDHRGMDLKVYVGPSISPGPFNVTVVTGQRAVLSCESTGIPAPQ-VSWRRNGSPISVDQSSAYRLMSSGSLVITSPTAEDEGYFECTVTN----------EVGEERRVIEVIL---QVPPVIKDDVSSVTAVKMSPVVLPC----HATGRPEPVISWNKNWMQLGARGGSYRVLPTGALEILAATPSHAGKYTCSARNPVGVAYKHVT--LTVQEPPEIRPMAEEVQVVLHH-----SVVLPCEVQGFPRPTITWQ--REGVPVAT------GHRLAVLSNGALKFSRVTL---------------GDAGTYQCLAQNEAGTA 3025 HSP 10 Score: 60.4622 bits (145), Expect = 1.916e-8 Identity = 98/448 (21.88%), Postives = 168/448 (37.50%), Query Frame = 3 Query: 663 EVSAISLWRPHYL--ENRGFVMCTAINDAGVLTKNTSLLNIKYKPKIKPFVPNTVNAMINQTIDLSCEVYANPAATIQWVIMQGLQ---------IIDSSKFIAKIRPDMDGPLICEAKNYLGSTKETVQLNVLRDPLIHIDSNYRVPKNSNYS------INCRVTSNPPPEFIKWYKLSNMTDSSAVLISDDAKLNFILIDRSSTGMYACVTQNIQISTTGKRKPANSEKTMFLTVTYKPKEPQILGNKIISIMKGEKFIIKCSTDRKSPGEPFPTLKW----IDVETKDIVSD---METFQVINSESRHNGKYKCLAENEIGKSFS----RETALVTVNEAPSIITQHKNRKVFLSYSDLPQSISFTCEFRGQPLYEARWRYGNEKIPPSSQDFKIEDHRNISNERISQIFTKLTIDLYSRTFSQQTSLRSSPNGRYNCEADNRHG 1922 E S + W Y ++ G C A + AG+ T L + P ++P P V + LSC++ + + W + +SS I+ +R GP C A N G ++ V L VL P + + P+ ++S I+C + +PPP+ + +++ + IS+ L +G Y C+ N ++ T + + V Y + +++ ++ GE ++C ++ G P P +KW +D+ T T Q+ + +G Y C+A N G S + + A T +E+P IT + + +I+ C RG P WR +D R I + + T L S Q S+ G Y CEA N+ G Sbjct: 473 EASGKASWEIPYASGDDEGAYECVARSTAGMGRALTQLTVREPPPVLRP--PVNVTSSPGTVAVLSCQIQGSVRHNLTWYRTGSALPSRSGRVRVLANSSLEISWVRSQDAGPYQCRASNAHGESQAVVWLVVLEAPSVVVS-----PQTQSFSLGAEVHISCSASGSPPPKVFWSHGNIFLSNHHRMSISESGMLTIRGAAPEDSGNYTCLATN-EVGTASQS----------VNVNYAEPPSISVVQQMVMVVAGEDASLEC----QASGTPSPIVKWQKGDLDLGTAPFAEQDVHRGTLQIRGVQELDSGDYTCVASNIAGSSSAVVVLQVGAAPTFSESPVDIT-----------ASVGDNITLPCIARGFPTPSLIWRR--------------QDGRPIFGKSSGHVGTS---QLPSGALQIQ-SVWVDDEGVYLCEAKNQFG 869 HSP 11 Score: 55.4546 bits (132), Expect = 6.090e-7 Identity = 100/445 (22.47%), Postives = 166/445 (37.30%), Query Frame = 3 Query: 318 VPDSESQITISHESRLTIHNISSDNSGYYVCRVTLLTTSEHIISLAVVTVKTPPKSISFHFNKSINVFQEQEFIAIQCSVSGGIPPPKISM------YIVKDNAIKRLKIISSNFPNSTIAEVSAISLWRPHYLENRGFVMCTAINDAGVLTKNTSLLNIKYKPKIKPFVPNTVNAMINQTIDLSCEVYANPAATIQW--VIMQ------GLQIIDSSKF-IAKIRPDMDGPLICEAKNYLGSTKETVQLNVLRDPLIH-IDSNYRVPKNSNYSINCRVTSNPPPEFIKWYK--LSNMTDSSAVLISDDAKLNFILIDRSSTGMYACVTQNIQISTTGKRKPANSEKTMFLTVTYKPKEPQILGNKIIS--IMKGEKFIIKCSTDRKSPGEPFPTLKWIDVETKDIVSDMETFQVINSESRH--------NGKYKCLAENEIGKS 1568 VP ++ T+ E L I + + G Y C V+ S+H + V P FN ++ Q A+ S GIP P++S V ++ RL S S A E+ G+ CT N+ G + ++ ++ P IK V ++V A+ + L C P I W MQ +++ + I P G C A+N +G + V L V P I + +V + + + C V P P I W + + T ++S+ A L F + G Y C+ QN + A ++ + L V P +L + ++ G+ + C D G+P P + W + V D ++ ++ S H G Y C A N +G++ Sbjct: 2713 VPLHNNRFTLLSEGSLRISTVQLSDVGRYYCSVSNQAGSDH--RGMDLKVYVGPSISPGPFNVTVVTGQR----AVLSCESTGIPAPQVSWRRNGSPISVDQSSAYRLMSSGSLVITSPTA-------------EDEGYFECTVTNEVGEERRVIEVI-LQVPPVIKDDV-SSVTAVKMSPVVLPCHATGRPEPVISWNKNWMQLGARGGSYRVLPTGALEILAATPSHAGKYTCSARNPVGVAYKHVTLTVQEPPEIRPMAEEVQVVLHHSVVLPCEVQGFPRPT-ITWQREGVPVATGHRLAVLSNGA-LKFSRVTLGDAGTYQCLAQN-------EAGTALAQTQLILQV------PPVLSVPRLEYVVVLGQPVSLDCVAD----GQPKPEVTW--HRDRRPVVDSSHLRLFSNGSLHITATQRGDAGIYTCSARNSVGRA 3115
BLAST of hemicentin-1 isoform X2 vs. Ensembl Zebrafish
Match: robo2 (roundabout, axon guidance receptor, homolog 2 (Drosophila) [Source:ZFIN;Acc:ZDB-GENE-001019-1]) HSP 1 Score: 91.6633 bits (226), Expect = 4.444e-18 Identity = 130/541 (24.03%), Postives = 205/541 (37.89%), Query Frame = 3 Query: 1020 LNVLRDPLIHIDSNYRVPKNSNYSINCRVTSNPPPEFIKWYKLSNMTDSSAVLIS-DDAKLNFILIDRSSTGMYACVTQNIQISTTGKRKPANSEKTMFLTVTYKPKEPQILGNKIISIMKGEKFI-IKCSTDRKSPGEPFPTLKWI--DVETKDIVSDME------TFQVINSESRHNGKYKCLAENEIGKSFSRETALVTV--NEAPSIITQHKNRKVFLSYSDLPQSISFTCEFRGQPLYEARWRYGNEKIPPSSQDFKIEDHRNISNERIS-QIFTKLTIDLYSRTFSQQTSLRSSPNGRYNCEADNRHG--IASLDYFLXXXXXXXXXXNIRHRKIAASLN-QNVVMIRCQAESISTMHIKWYKTNEHIVLPFQSKKYSIFEAEVTKYEPERDLFTPGLKVNELTIKDLENDDFSNYSCVASNDQG---------IKKVNFEVVFKSQ-----PDPPYDLRVTDFEWDSVTINWKPGFNGGLT-QNYEILVISENFGTQNVPFYSDKNENTLTITGLYPSTPYEIRIYAVNSIGRS 2549 ++VLRD ++ V + C P I W K D I KL +S GMY CV N+ G+R ++ T+F + P L I ++ E+ + +C G+P P+++W DVE DM+ T ++ + + G + C+AEN +GK + T V V + AP + + +++ V ++ SF CE +G P W+ SQ+ + N R S LTI T+++ + G Y C+A G +A + IR +L +V ++RC A I W K + + L + + S+ +DL L IK L D Y+CVA++ G +K+ VV K + P PP +VTD +SV+++W+PG G Y I S++ TI GL P+T Y + AVN G S Sbjct: 1 VSVLRDDFRQNPTDVVVAAGEPAILECVPPRGHPEPTIYWKKDKVRIDEKDDRIKIRGGKLMISNTRKSDAGMYICVGTNM----VGERDSETAQVTVF-------ERPTFLRRPINQVVLEEEAVEFRCQVQ----GDPQPSIRWKKDDVEIPRGRYDMKFDKDDFTLRIKKATASDEGTFTCVAENRVGKMEASATLTVRVLGSAAPQFVIRPRDQIVAQG-----RTASFPCETKGNPQPAVFWQK------EGSQNLLFPNQPQQPNSRFSVSPSGDLTI----------TTVQRADAGYYICQALTVAGSILAKAQLEVTDVLTDRPPPIIRQGPANQTLGVDSVALLRCHASGEPVPTISWLK--DGVSLLGKDPRMSL-----------QDL-------GSLQIKGLRLSDSGIYTCVAASSSGETSWSAFLEVKEAGSLVVVKDRDENELPGPPSKPQVTDVTKNSVSLSWQPGLPGASAISTYVIEAFSQSVSNSWQTVADHAKTTQYTIKGLRPNTIYLFMVRAVNVQGLS 485 HSP 2 Score: 55.8398 bits (133), Expect = 4.305e-7 Identity = 75/342 (21.93%), Postives = 129/342 (37.72%), Query Frame = 3 Query: 705 NRGFVMCTAINDAGVLTKNTSLLNIKYKPKIKPFVPNTVNAMI--NQTIDLSCEVYANPAATIQWV-----IMQGL--QIIDSSKFIAKIRPDM---DGPLICEAKNYLGSTKETVQLNVL----RDPLIHIDSNYR-VPKNSNYSINCRVTSNPPPEFIKWYKLSNMT---------DSSAVLISDDAKLNFILIDRSSTGMYACVTQNIQISTTGKRKPANSEKTMFLTVTYKPKEPQILGNKIISIMKGEKFIIKCSTDRKSPGEPFPTLKWIDVETKDIVS-----------DMETFQVINSESRHNGKYKCLAENEIGKSFSRETALVTVNEAPSII 1619 + G +C N G T+ + + +P F+ +N ++ + ++ C+V +P +I+W I +G D F +I+ +G C A+N +G + + L V P I + V + S C NP P W K + +S +S L + R+ G Y C + S K A E T LT P Q N+ + + +++C + GEP PT+ W+ KD VS D+ + Q+ +G Y C+A + G+ + +A + V EA S++ Sbjct: 70 DAGMYICVGTNMVGERDSETAQVTVFERPT---FLRRPINQVVLEEEAVEFRCQVQGDPQPSIRWKKDDVEIPRGRYDMKFDKDDFTLRIKKATASDEGTFTCVAENRVGKMEASATLTVRVLGSAAPQFVIRPRDQIVAQGRTASFPCETKGNPQPAVF-WQKEGSQNLLFPNQPQQPNSRFSVSPSGDLTITTVQRADAGYYICQALTVAGSILAK---AQLEVTDVLTDRPPPIIRQGPANQTLGV--DSVALLRC----HASGEPVPTISWL----KDGVSLLGKDPRMSLQDLGSLQIKGLRLSDSGIYTCVAASSSGE--TSWSAFLEVKEAGSLV 392
BLAST of hemicentin-1 isoform X2 vs. Ensembl Zebrafish
Match: robo2 (roundabout, axon guidance receptor, homolog 2 (Drosophila) [Source:ZFIN;Acc:ZDB-GENE-001019-1]) HSP 1 Score: 91.6633 bits (226), Expect = 4.444e-18 Identity = 130/541 (24.03%), Postives = 205/541 (37.89%), Query Frame = 3 Query: 1020 LNVLRDPLIHIDSNYRVPKNSNYSINCRVTSNPPPEFIKWYKLSNMTDSSAVLIS-DDAKLNFILIDRSSTGMYACVTQNIQISTTGKRKPANSEKTMFLTVTYKPKEPQILGNKIISIMKGEKFI-IKCSTDRKSPGEPFPTLKWI--DVETKDIVSDME------TFQVINSESRHNGKYKCLAENEIGKSFSRETALVTV--NEAPSIITQHKNRKVFLSYSDLPQSISFTCEFRGQPLYEARWRYGNEKIPPSSQDFKIEDHRNISNERIS-QIFTKLTIDLYSRTFSQQTSLRSSPNGRYNCEADNRHG--IASLDYFLXXXXXXXXXXNIRHRKIAASLN-QNVVMIRCQAESISTMHIKWYKTNEHIVLPFQSKKYSIFEAEVTKYEPERDLFTPGLKVNELTIKDLENDDFSNYSCVASNDQG---------IKKVNFEVVFKSQ-----PDPPYDLRVTDFEWDSVTINWKPGFNGGLT-QNYEILVISENFGTQNVPFYSDKNENTLTITGLYPSTPYEIRIYAVNSIGRS 2549 ++VLRD ++ V + C P I W K D I KL +S GMY CV N+ G+R ++ T+F + P L I ++ E+ + +C G+P P+++W DVE DM+ T ++ + + G + C+AEN +GK + T V V + AP + + +++ V ++ SF CE +G P W+ SQ+ + N R S LTI T+++ + G Y C+A G +A + IR +L +V ++RC A I W K + + L + + S+ +DL L IK L D Y+CVA++ G +K+ VV K + P PP +VTD +SV+++W+PG G Y I S++ TI GL P+T Y + AVN G S Sbjct: 1 VSVLRDDFRQNPTDVVVAAGEPAILECVPPRGHPEPTIYWKKDKVRIDEKDDRIKIRGGKLMISNTRKSDAGMYICVGTNM----VGERDSETAQVTVF-------ERPTFLRRPINQVVLEEEAVEFRCQVQ----GDPQPSIRWKKDDVEIPRGRYDMKFDKDDFTLRIKKATASDEGTFTCVAENRVGKMEASATLTVRVLGSAAPQFVIRPRDQIVAQG-----RTASFPCETKGNPQPAVFWQK------EGSQNLLFPNQPQQPNSRFSVSPSGDLTI----------TTVQRADAGYYICQALTVAGSILAKAQLEVTDVLTDRPPPIIRQGPANQTLGVDSVALLRCHASGEPVPTISWLK--DGVSLLGKDPRMSL-----------QDL-------GSLQIKGLRLSDSGIYTCVAASSSGETSWSAFLEVKEAGSLVVVKDRDENELPGPPSKPQVTDVTKNSVSLSWQPGLPGASAISTYVIEAFSQSVSNSWQTVADHAKTTQYTIKGLRPNTIYLFMVRAVNVQGLS 485 HSP 2 Score: 55.8398 bits (133), Expect = 4.305e-7 Identity = 75/342 (21.93%), Postives = 129/342 (37.72%), Query Frame = 3 Query: 705 NRGFVMCTAINDAGVLTKNTSLLNIKYKPKIKPFVPNTVNAMI--NQTIDLSCEVYANPAATIQWV-----IMQGL--QIIDSSKFIAKIRPDM---DGPLICEAKNYLGSTKETVQLNVL----RDPLIHIDSNYR-VPKNSNYSINCRVTSNPPPEFIKWYKLSNMT---------DSSAVLISDDAKLNFILIDRSSTGMYACVTQNIQISTTGKRKPANSEKTMFLTVTYKPKEPQILGNKIISIMKGEKFIIKCSTDRKSPGEPFPTLKWIDVETKDIVS-----------DMETFQVINSESRHNGKYKCLAENEIGKSFSRETALVTVNEAPSII 1619 + G +C N G T+ + + +P F+ +N ++ + ++ C+V +P +I+W I +G D F +I+ +G C A+N +G + + L V P I + V + S C NP P W K + +S +S L + R+ G Y C + S K A E T LT P Q N+ + + +++C + GEP PT+ W+ KD VS D+ + Q+ +G Y C+A + G+ + +A + V EA S++ Sbjct: 70 DAGMYICVGTNMVGERDSETAQVTVFERPT---FLRRPINQVVLEEEAVEFRCQVQGDPQPSIRWKKDDVEIPRGRYDMKFDKDDFTLRIKKATASDEGTFTCVAENRVGKMEASATLTVRVLGSAAPQFVIRPRDQIVAQGRTASFPCETKGNPQPAVF-WQKEGSQNLLFPNQPQQPNSRFSVSPSGDLTITTVQRADAGYYICQALTVAGSILAK---AQLEVTDVLTDRPPPIIRQGPANQTLGV--DSVALLRC----HASGEPVPTISWL----KDGVSLLGKDPRMSLQDLGSLQIKGLRLSDSGIYTCVAASSSGE--TSWSAFLEVKEAGSLV 392
BLAST of hemicentin-1 isoform X2 vs. Ensembl Xenopus
Match: lrrc8c (leucine rich repeat containing 8 VRAC subunit C [Source:Xenbase;Acc:XB-GENE-5797483]) HSP 1 Score: 111.694 bits (278), Expect = 5.254e-24 Identity = 153/671 (22.80%), Postives = 268/671 (39.94%), Query Frame = 3 Query: 714 FVMCTAINDAGVLTKNTSLLNIKYKPKIKPFVPNTVNAMINQTIDLSCEVYANPAATIQWVIMQGLQIIDSSK----------------FI-----AKIRPDMDGPLICEAKNYLG---STKETVQLNVLRDPLIHIDSNYRVPKNSNYSINCRVTSNPPPEFIKWYKLSNM--TDSSAVLISDDAKLNFILIDRSSTGMYACVTQNIQISTTGKRKPANSEKTMFLTVTYKPKEPQILGNKIISIMKGEKFIIKCSTDRKSPGEPFPTLKWIDVE-----TKDIVSDMETFQVINSESRHNGKYKCLAENEIGKSFSRETALVTVNEAPSIITQHKNRKVFLSYSDLPQSISFTCEFRGQPLYEARW-RYGNEKIPPSSQDFKIEDHRNISNERISQIFTKLTIDLYSRTFSQQTSLRSSPNGRYNCEADNRHGIASLDYFLXXXXXXXXXXNIRHRKIAASLNQNV-----VMIRCQAESISTMHIKWYKTNEHIVLPFQSKKYSIFEAEVTKYEPERDLFTPGLKVNELTIKDLENDDFSNYSCVASNDQGIKKVNFEVVFKSQ-----------------PDPPYDLRVTDFEWDSVTINWKPGFNGGLT-QNYEILVISENFGTQNVPFYSDKNENTLTITGLYPSTPYEIRIYAVNSIGRSLNSE 2561 F++C + LT + L + P+I P+ + + L+C+ P TI+W +G +++ K F+ KIRPD +G +C A+NYLG S ++++ +LRD S+ V + C+ P I W K D + KL +S G Y CV N+ G+R+ +E LTV +P + N +++ +F KC ++ G+P PT++W + ++ + D T ++ + G Y C+AEN +GK + +A++TV E P+ + + +++ V L ++++F CE G P W + G++ + F + ++ S +SQ LTI T+++ S G Y C+ N G + FL + + R+ +NQ V +++ C A I I W K + I++P Q + ++ L I+ + D Y+C AS G + N+ + Q P P VTD ++VT++W+P N G T +Y I S G+ + ++ + L P+ Y + AVN+ G S S+ Sbjct: 9 FLLCGIM----CLTSGSRLRQEDFPPRIVEH-PSDLIVSKGEPATLNCKAEGRPTPTIEW--YKGGDKVETDKDDPRSHRMLLPSGSLFFLRIVHGRKIRPD-EGVYVCVARNYLGEAVSHNASLEVAILRDDFRQNPSDVMVAVGEPAVMECQPPRGHPEPTISWKKDGTPIDDDKDERITIRGGKLMITYTRKSDAGKYVCVGTNM----VGERESEVAE----LTVLERPSFVRRPSNMAVTVDDSVEF--KC----EARGDPVPTVRWRKDDGDLPKSRYEIRDDHTLKIRKVTAGDMGSYTCVAENMVGK--AEASAVLTVQEPPNFVVKPRDQVVALG-----RTVTFQCEATGNPQPAIFWQKEGSQNL-----LFSYQPPQSSSRFSVSQT-GDLTI----------TTVQKSDVGYYICQTLNVAGSITTKAFLEVTDVVADRPPPVIRQ--GPVNQTVAVDGTLIMNCIASGIPVPTIHWRK--DGILIPTQDSRIKQQDS------------------GALQIRYAKLSDTGRYTCTASTTSG--EANWSAYIEVQEFGVPVQPPRATDPNLIPSAPSKPEVTDVSKNTVTLSWQPNLNSGATPTSYLIEAFSHASGSSWQTVAENVKTDSFAVKALKPNAIYLFLVRAVNAYGLSDPSQ 610 HSP 2 Score: 63.929 bits (154), Expect = 1.808e-9 Identity = 96/429 (22.38%), Postives = 152/429 (35.43%), Query Frame = 3 Query: 390 NSGYYVC--RVTLLTTSEHIISLAVVTVKTPPKSISFHFNKSINVFQEQEFIAIQCSVSGGIPPPKISM----YIVKDNAIKRLKIISSNFPNSTIAEVSAISLWRPHYLENRGFVMCTAINDAGVLTKNTSLLNIKYKPKIKPFV--PNTVNAMINQTIDLSCEVYANPAATIQWVIMQG------LQIIDSSKF-IAKIRPDMDGPLICEAKNYLGSTKETVQLNVLRDP-LIHIDSNYRVPKNSNYSINCRVTSNPPPEFIKWYKLSNMT---------DSSAVLISDDAKLNFILIDRSSTGMYACVTQNIQISTTGKRKPANSEKTMFLTVT--YKPKEPQILGNKII--SIMKGEKFIIKCSTDRKSPGEPFPTLKW----IDVETKDI---VSDMETFQVINSESRHNGKYKCLAENEIGKS 1568 + G YVC R L H SL V ++ F N S + E ++C G P P IS + D+ +R+ I I+ R + G +C N G + L + +P FV P+ + ++ +++ CE +P T++W G +I D I K+ G C A+N +G + + L V P + + V + C T NP P I W K + SS +S L + +S G Y C T N+ S T K FL VT + P ++ + ++ I+ C G P PT+ W I + T+D D Q+ ++ G+Y C A G++ Sbjct: 103 DEGVYVCVARNYLGEAVSHNASLEVAILRD-----DFRQNPSDVMVAVGEPAVMECQPPRGHPEPTISWKKDGTPIDDDKDERITIRGGKL---------MITYTR---KSDAGKYVCVGTNMVGERESEVAELTVLERPS---FVRRPSNMAVTVDDSVEFKCEARGDPVPTVRWRKDDGDLPKSRYEIRDDHTLKIRKVTAGDMGSYTCVAENMVGKAEASAVLTVQEPPNFVVKPRDQVVALGRTVTFQCEATGNPQPA-IFWQKEGSQNLLFSYQPPQSSSRFSVSQTGDLTITTVQKSDVGYYICQTLNVAGSITTK---------AFLEVTDVVADRPPPVIRQGPVNQTVAVDGTLIMNCIAS----GIPVPTIHWRKDGILIPTQDSRIKQQDSGALQIRYAKLSDTGRYTCTASTTSGEA 497
BLAST of hemicentin-1 isoform X2 vs. Ensembl Xenopus
Match: lrrc8c (leucine rich repeat containing 8 VRAC subunit C [Source:Xenbase;Acc:XB-GENE-5797483]) HSP 1 Score: 110.923 bits (276), Expect = 7.497e-24 Identity = 145/626 (23.16%), Postives = 251/626 (40.10%), Query Frame = 3 Query: 849 LSCEVYANPAATIQWVIMQGLQIIDSSK----------------FIA-----KIRPDMDGPLICEAKNYLG---STKETVQLNVLRDPLIHIDSNYRVPKNSNYSINCRVTSNPPPEFIKWYKLSNMTDSS--AVLISDDAKLNFILIDRSSTGMYACVTQNIQISTTGKRKPANSEKTMFLTVTYKPKEPQILGNKIISIMKGEKFIIKCSTDRKSPGEPFPTLKWIDVE-----TKDIVSDMETFQVINSESRHNGKYKCLAENEIGKSFSRETALVTVNEAPSIITQHKNRKVFLSYSDLPQSISFTCEFRGQPLYEARW-RYGNEKIPPSSQDFKIEDHRNISNERISQIFTKLTIDLYSRTFSQQTSLRSSPNGRYNCEADNRHGIASLDYFLXXXXXXXXXXNIRHRKIAASLNQNV-----VMIRCQAESISTMHIKWYKTNEHIVLPFQSKKYSIFEAEVTKYEPERDLFTPGLKVNELTIKDLENDDFSNYSCVASNDQGIKKVNFEVVFKSQ-----------------PDPPYDLRVTDFEWDSVTINWKPGFNGGLT-QNYEILVISENFGTQNVPFYSDKNENTLTITGLYPSTPYEIRIYAVNSIGRSLNSE 2561 L+C+ P TI+W +G +++ K F+ KIRPD +G +C A+NYLG S ++++ +LRD S+ V + C+ P I W K D + KL +S G Y CV N+ G+R+ +E LTV +P + N +++ +F KC ++ G+P PT++W + ++ + D T ++ + G Y C+AEN +GK+ +A++TV E P+ + + +++ V L ++++F CE G P W + G++ + F + ++ S +SQ LTI T+++ S G Y C+ N G + FL + + R+ +NQ V +++ C A I I W K + I++P Q + ++ L I+ + D Y+C AS G + N+ + Q P P VTD ++VT++W+P N G T +Y I S G+ + ++ + L P+ Y + AVN+ G S S+ Sbjct: 40 LNCKAEGRPTPTIEW--YKGGDKVETDKDDPRSHRMLLPSGSLFFLRIVHGRKIRPD-EGVYVCVARNYLGEAVSHNASLEVAILRDDFRQNPSDVMVAVGEPAVMECQPPRGHPEPTISWKKDGTPIDDDKDERITIRGGKLMITYTRKSDAGKYVCVGTNM----VGERESEVAE----LTVLERPSFVRRPSNMAVTVDDSVEF--KC----EARGDPVPTVRWRKDDGDLPKSRYEIRDDHTLKIRKVTAGDMGSYTCVAENMVGKA--EASAVLTVQEPPNFVVKPRDQVVALG-----RTVTFQCEATGNPQPAIFWQKEGSQNL-----LFSYQPPQSSSRFSVSQT-GDLTI----------TTVQKSDVGYYICQTLNVAGSITTKAFLEVTDVVADRPPPVIRQ--GPVNQTVAVDGTLIMNCIASGIPVPTIHWRK--DGILIPTQDSRIKQQDS------------------GALQIRYAKLSDTGRYTCTASTTSG--EANWSAYIEVQEFGVPVQPPRATDPNLIPSAPSKPEVTDVSKNTVTLSWQPNLNSGATPTSYLIEAFSHASGSSWQTVAENVKTDSFAVKALKPNAIYLFLVRAVNAYGLSDPSQ 601 HSP 2 Score: 74.3294 bits (181), Expect = 1.364e-12 Identity = 100/451 (22.17%), Postives = 163/451 (36.14%), Query Frame = 3 Query: 1041 LIHIDSNYRVPKNSNYSINCRVTSNPPPEFIKWYKLSNMTDS------SAVLISDDAKLNFILID-----RSSTGMYACVTQNIQISTTGKRKPANSEKTMFLTVTYKPKEPQILGNKIISIMKGEKFIIKCSTDRKSPGEPFPTLKWI-------DVETKDIVSDMETFQVINSESRHNGKYKCLAENEIGKSFSRETALVTVNEAPSIITQHKNRKVFLSYSDLPQSISFTCEFRGQPLYEARWRYGNEKIPPSSQDFKIEDHRNISNERISQIFTKLTIDLYSRTFSQQTSLRSSPNGRYNCEADNRHGIASLDYFLXXXXXXXXXXNIRHRKIAASLNQNVVMIRCQAESISTMHIKWYKTNEHIVL-----PFQSKKYSIFEAEVTKYEPERDLFTPGLKVNELTIKDLENDDFSNYSCVASNDQG--IKKVNFEV--VFKSQPDP 2312 ++ S+ V K ++NC+ P P I+WYK + ++ S ++ L F+ I R G+Y CV +N S + L ++ ++ + GE +++C R G P PT+ W D + + I + + GKY C+ N +G+ S E A +TV E PS + + N V + S+ F CE RG P+ RWR + +P S ++I D + +++ + G Y C A+N G A L ++ PP R + +A V +C+A I W K +L P S ++S+ + +LTI ++ D Y C N G K EV V +P P Sbjct: 23 IVEHPSDLIVSKGEPATLNCKAEGRPTPT-IEWYKGGDKVETDKDDPRSHRMLLPSGSLFFLRIVHGRKIRPDEGVYVCVARNYLGEAVSHNA---SLEVAILRDDFRQNPSDVM------VAVGEPAVMECQPPR---GHPEPTISWKKDGTPIDDDKDERITIRGGKLMITYTRKSDAGKYVCVGTNMVGERES-EVAELTVLERPSFVRRPSNMAVTVD-----DSVEFKCEARGDPVPTVRWRKDDGDLPKSR--YEIRDDHTLKIRKVT----------------------AGDMGSYTCVAENMVGKAEASAVLTVQEPPNFVVKPRDQVVALG---RTVTFQCEATGNPQPAIFWQKEGSQNLLFSYQPPQSSSRFSVSQ------------------TGDLTITTVQKSDVGYYICQTLNVAGSITTKAFLEVTDVVADRPPP 409 HSP 3 Score: 63.929 bits (154), Expect = 1.719e-9 Identity = 96/429 (22.38%), Postives = 152/429 (35.43%), Query Frame = 3 Query: 390 NSGYYVC--RVTLLTTSEHIISLAVVTVKTPPKSISFHFNKSINVFQEQEFIAIQCSVSGGIPPPKISM----YIVKDNAIKRLKIISSNFPNSTIAEVSAISLWRPHYLENRGFVMCTAINDAGVLTKNTSLLNIKYKPKIKPFV--PNTVNAMINQTIDLSCEVYANPAATIQWVIMQG------LQIIDSSKF-IAKIRPDMDGPLICEAKNYLGSTKETVQLNVLRDP-LIHIDSNYRVPKNSNYSINCRVTSNPPPEFIKWYKLSNMT---------DSSAVLISDDAKLNFILIDRSSTGMYACVTQNIQISTTGKRKPANSEKTMFLTVT--YKPKEPQILGNKII--SIMKGEKFIIKCSTDRKSPGEPFPTLKW----IDVETKDI---VSDMETFQVINSESRHNGKYKCLAENEIGKS 1568 + G YVC R L H SL V ++ F N S + E ++C G P P IS + D+ +R+ I I+ R + G +C N G + L + +P FV P+ + ++ +++ CE +P T++W G +I D I K+ G C A+N +G + + L V P + + V + C T NP P I W K + SS +S L + +S G Y C T N+ S T K FL VT + P ++ + ++ I+ C G P PT+ W I + T+D D Q+ ++ G+Y C A G++ Sbjct: 94 DEGVYVCVARNYLGEAVSHNASLEVAILRD-----DFRQNPSDVMVAVGEPAVMECQPPRGHPEPTISWKKDGTPIDDDKDERITIRGGKL---------MITYTR---KSDAGKYVCVGTNMVGERESEVAELTVLERPS---FVRRPSNMAVTVDDSVEFKCEARGDPVPTVRWRKDDGDLPKSRYEIRDDHTLKIRKVTAGDMGSYTCVAENMVGKAEASAVLTVQEPPNFVVKPRDQVVALGRTVTFQCEATGNPQPA-IFWQKEGSQNLLFSYQPPQSSSRFSVSQTGDLTITTVQKSDVGYYICQTLNVAGSITTK---------AFLEVTDVVADRPPPVIRQGPVNQTVAVDGTLIMNCIAS----GIPVPTIHWRKDGILIPTQDSRIKQQDSGALQIRYAKLSDTGRYTCTASTTSGEA 488
BLAST of hemicentin-1 isoform X2 vs. Ensembl Xenopus
Match: lrrc8c (leucine rich repeat containing 8 VRAC subunit C [Source:Xenbase;Acc:XB-GENE-5797483]) HSP 1 Score: 110.923 bits (276), Expect = 9.069e-24 Identity = 154/679 (22.68%), Postives = 271/679 (39.91%), Query Frame = 3 Query: 705 NRGFVMCTAI-----NDAGVLTKNTSLLNIKYKPKIKPFVPNTVNAMINQTIDLSCEVYANPAATIQWVIMQGLQIIDSSK----------------FIA-----KIRPDMDGPLICEAKNYLG---STKETVQLNVLRDPLIHIDSNYRVPKNSNYSINCRVTSNPPPEFIKWYKLSNM--TDSSAVLISDDAKLNFILIDRSSTGMYACVTQNIQISTTGKRKPANSEKTMFLTVTYKPKEPQILGNKIISIMKGEKFIIKCSTDRKSPGEPFPTLKWIDVE-----TKDIVSDMETFQVINSESRHNGKYKCLAENEIGKSFSRETALVTVNEAPSIITQHKNRKVFLSYSDLPQSISFTCEFRGQPLYEARW-RYGNEKIPPSSQDFKIEDHRNISNERISQIFTKLTIDLYSRTFSQQTSLRSSPNGRYNCEADNRHGIASLDYFLXXXXXXXXXXNIRHRKIAASLNQNV-----VMIRCQAESISTMHIKWYKTNEHIVLPFQSKKYSIFEAEVTKYEPERDLFTPGLKVNELTIKDLENDDFSNYSCVASNDQGIKKVNFEVVFKSQ-----------------PDPPYDLRVTDFEWDSVTINWKPGFNGGLT-QNYEILVISENFGTQNVPFYSDKNENTLTITGLYPSTPYEIRIYAVNSIGRSLNSE 2561 +RG TA+ +D ++ + L + P+I P+ + + L+C+ P TI+W +G +++ K F+ KIRPD +G +C A+NYLG S ++++ +LRD S+ V + C+ P I W K D + KL +S G Y CV N+ G+R+ +E LTV +P + N +++ +F KC ++ G+P PT++W + ++ + D T ++ + G Y C+AEN +GK+ +A++TV E P+ + + +++ V L ++++F CE G P W + G++ + F + ++ S +SQ LTI T+++ S G Y C+ N G + FL + + R+ +NQ V +++ C A I I W K + I++P Q + ++ L I+ + D Y+C AS G + N+ + Q P P VTD ++VT++W+P N G T +Y I S G+ + ++ + L P+ Y + AVN+ G S S+ Sbjct: 37 DRGLDSGTALPTSDHDDNSLVYTGSRLRQEDFPPRIVEH-PSDLIVSKGEPATLNCKAEGRPTPTIEW--YKGGDKVETDKDDPRSHRMLLPSGSLFFLRIVHGRKIRPD-EGVYVCVARNYLGEAVSHNASLEVAILRDDFRQNPSDVMVAVGEPAVMECQPPRGHPEPTISWKKDGTPIDDDKDERITIRGGKLMITYTRKSDAGKYVCVGTNM----VGERESEVAE----LTVLERPSFVRRPSNMAVTVDDSVEF--KC----EARGDPVPTVRWRKDDGDLPKSRYEIRDDHTLKIRKVTAGDMGSYTCVAENMVGKA--EASAVLTVQEPPNFVVKPRDQVVALG-----RTVTFQCEATGNPQPAIFWQKEGSQNL-----LFSYQPPQSSSRFSVSQT-GDLTI----------TTVQKSDVGYYICQTLNVAGSITTKAFLEVTDVVADRPPPVIRQ--GPVNQTVAVDGTLIMNCIASGIPVPTIHWRK--DGILIPTQDSRIKQQDS------------------GALQIRYAKLSDTGRYTCTASTTSG--EANWSAYIEVQEFGVPVQPPRATDPNLIPSAPSKPEVTDVSKNTVTLSWQPNLNSGATPTSYLIEAFSHASGSSWQTVAENVKTDSFAVKALKPNAIYLFLVRAVNAYGLSDPSQ 650 HSP 2 Score: 64.3142 bits (155), Expect = 1.615e-9 Identity = 96/429 (22.38%), Postives = 152/429 (35.43%), Query Frame = 3 Query: 390 NSGYYVC--RVTLLTTSEHIISLAVVTVKTPPKSISFHFNKSINVFQEQEFIAIQCSVSGGIPPPKISM----YIVKDNAIKRLKIISSNFPNSTIAEVSAISLWRPHYLENRGFVMCTAINDAGVLTKNTSLLNIKYKPKIKPFV--PNTVNAMINQTIDLSCEVYANPAATIQWVIMQG------LQIIDSSKF-IAKIRPDMDGPLICEAKNYLGSTKETVQLNVLRDP-LIHIDSNYRVPKNSNYSINCRVTSNPPPEFIKWYKLSNMT---------DSSAVLISDDAKLNFILIDRSSTGMYACVTQNIQISTTGKRKPANSEKTMFLTVT--YKPKEPQILGNKII--SIMKGEKFIIKCSTDRKSPGEPFPTLKW----IDVETKDI---VSDMETFQVINSESRHNGKYKCLAENEIGKS 1568 + G YVC R L H SL V ++ F N S + E ++C G P P IS + D+ +R+ I I+ R + G +C N G + L + +P FV P+ + ++ +++ CE +P T++W G +I D I K+ G C A+N +G + + L V P + + V + C T NP P I W K + SS +S L + +S G Y C T N+ S T K FL VT + P ++ + ++ I+ C G P PT+ W I + T+D D Q+ ++ G+Y C A G++ Sbjct: 143 DEGVYVCVARNYLGEAVSHNASLEVAILRD-----DFRQNPSDVMVAVGEPAVMECQPPRGHPEPTISWKKDGTPIDDDKDERITIRGGKL---------MITYTR---KSDAGKYVCVGTNMVGERESEVAELTVLERPS---FVRRPSNMAVTVDDSVEFKCEARGDPVPTVRWRKDDGDLPKSRYEIRDDHTLKIRKVTAGDMGSYTCVAENMVGKAEASAVLTVQEPPNFVVKPRDQVVALGRTVTFQCEATGNPQPA-IFWQKEGSQNLLFSYQPPQSSSRFSVSQTGDLTITTVQKSDVGYYICQTLNVAGSITTK---------AFLEVTDVVADRPPPVIRQGPVNQTVAVDGTLIMNCIAS----GIPVPTIHWRKDGILIPTQDSRIKQQDSGALQIRYAKLSDTGRYTCTASTTSGEA 537
BLAST of hemicentin-1 isoform X2 vs. Ensembl Xenopus
Match: lrrc8c (leucine rich repeat containing 8 VRAC subunit C [Source:Xenbase;Acc:XB-GENE-5797483]) HSP 1 Score: 110.538 bits (275), Expect = 1.072e-23 Identity = 154/679 (22.68%), Postives = 271/679 (39.91%), Query Frame = 3 Query: 705 NRGFVMCTAI-----NDAGVLTKNTSLLNIKYKPKIKPFVPNTVNAMINQTIDLSCEVYANPAATIQWVIMQGLQIIDSSK----------------FIA-----KIRPDMDGPLICEAKNYLG---STKETVQLNVLRDPLIHIDSNYRVPKNSNYSINCRVTSNPPPEFIKWYKLSNM--TDSSAVLISDDAKLNFILIDRSSTGMYACVTQNIQISTTGKRKPANSEKTMFLTVTYKPKEPQILGNKIISIMKGEKFIIKCSTDRKSPGEPFPTLKWIDVE-----TKDIVSDMETFQVINSESRHNGKYKCLAENEIGKSFSRETALVTVNEAPSIITQHKNRKVFLSYSDLPQSISFTCEFRGQPLYEARW-RYGNEKIPPSSQDFKIEDHRNISNERISQIFTKLTIDLYSRTFSQQTSLRSSPNGRYNCEADNRHGIASLDYFLXXXXXXXXXXNIRHRKIAASLNQNV-----VMIRCQAESISTMHIKWYKTNEHIVLPFQSKKYSIFEAEVTKYEPERDLFTPGLKVNELTIKDLENDDFSNYSCVASNDQGIKKVNFEVVFKSQ-----------------PDPPYDLRVTDFEWDSVTINWKPGFNGGLT-QNYEILVISENFGTQNVPFYSDKNENTLTITGLYPSTPYEIRIYAVNSIGRSLNSE 2561 +RG TA+ +D ++ + L + P+I P+ + + L+C+ P TI+W +G +++ K F+ KIRPD +G +C A+NYLG S ++++ +LRD S+ V + C+ P I W K D + KL +S G Y CV N+ G+R+ +E LTV +P + N +++ +F KC ++ G+P PT++W + ++ + D T ++ + G Y C+AEN +GK+ +A++TV E P+ + + +++ V L ++++F CE G P W + G++ + F + ++ S +SQ LTI T+++ S G Y C+ N G + FL + + R+ +NQ V +++ C A I I W K + I++P Q + ++ L I+ + D Y+C AS G + N+ + Q P P VTD ++VT++W+P N G T +Y I S G+ + ++ + L P+ Y + AVN+ G S S+ Sbjct: 37 DRGLDSGTALPTSDHDDNSLVYTGSRLRQEDFPPRIVEH-PSDLIVSKGEPATLNCKAEGRPTPTIEW--YKGGDKVETDKDDPRSHRMLLPSGSLFFLRIVHGRKIRPD-EGVYVCVARNYLGEAVSHNASLEVAILRDDFRQNPSDVMVAVGEPAVMECQPPRGHPEPTISWKKDGTPIDDDKDERITIRGGKLMITYTRKSDAGKYVCVGTNM----VGERESEVAE----LTVLERPSFVRRPSNMAVTVDDSVEF--KC----EARGDPVPTVRWRKDDGDLPKSRYEIRDDHTLKIRKVTAGDMGSYTCVAENMVGKA--EASAVLTVQEPPNFVVKPRDQVVALG-----RTVTFQCEATGNPQPAIFWQKEGSQNL-----LFSYQPPQSSSRFSVSQT-GDLTI----------TTVQKSDVGYYICQTLNVAGSITTKAFLEVTDVVADRPPPVIRQ--GPVNQTVAVDGTLIMNCIASGIPVPTIHWRK--DGILIPTQDSRIKQQDS------------------GALQIRYAKLSDTGRYTCTASTTSG--EANWSAYIEVQEFGVPVQPPRATDPNLIPSAPSKPEVTDVSKNTVTLSWQPNLNSGATPTSYLIEAFSHASGSSWQTVAENVKTDSFAVKALKPNAIYLFLVRAVNAYGLSDPSQ 650 HSP 2 Score: 64.3142 bits (155), Expect = 1.587e-9 Identity = 96/429 (22.38%), Postives = 152/429 (35.43%), Query Frame = 3 Query: 390 NSGYYVC--RVTLLTTSEHIISLAVVTVKTPPKSISFHFNKSINVFQEQEFIAIQCSVSGGIPPPKISM----YIVKDNAIKRLKIISSNFPNSTIAEVSAISLWRPHYLENRGFVMCTAINDAGVLTKNTSLLNIKYKPKIKPFV--PNTVNAMINQTIDLSCEVYANPAATIQWVIMQG------LQIIDSSKF-IAKIRPDMDGPLICEAKNYLGSTKETVQLNVLRDP-LIHIDSNYRVPKNSNYSINCRVTSNPPPEFIKWYKLSNMT---------DSSAVLISDDAKLNFILIDRSSTGMYACVTQNIQISTTGKRKPANSEKTMFLTVT--YKPKEPQILGNKII--SIMKGEKFIIKCSTDRKSPGEPFPTLKW----IDVETKDI---VSDMETFQVINSESRHNGKYKCLAENEIGKS 1568 + G YVC R L H SL V ++ F N S + E ++C G P P IS + D+ +R+ I I+ R + G +C N G + L + +P FV P+ + ++ +++ CE +P T++W G +I D I K+ G C A+N +G + + L V P + + V + C T NP P I W K + SS +S L + +S G Y C T N+ S T K FL VT + P ++ + ++ I+ C G P PT+ W I + T+D D Q+ ++ G+Y C A G++ Sbjct: 143 DEGVYVCVARNYLGEAVSHNASLEVAILRD-----DFRQNPSDVMVAVGEPAVMECQPPRGHPEPTISWKKDGTPIDDDKDERITIRGGKL---------MITYTR---KSDAGKYVCVGTNMVGERESEVAELTVLERPS---FVRRPSNMAVTVDDSVEFKCEARGDPVPTVRWRKDDGDLPKSRYEIRDDHTLKIRKVTAGDMGSYTCVAENMVGKAEASAVLTVQEPPNFVVKPRDQVVALGRTVTFQCEATGNPQPA-IFWQKEGSQNLLFSYQPPQSSSRFSVSQTGDLTITTVQKSDVGYYICQTLNVAGSITTK---------AFLEVTDVVADRPPPVIRQGPVNQTVAVDGTLIMNCIAS----GIPVPTIHWRKDGILIPTQDSRIKQQDSGALQIRYAKLSDTGRYTCTASTTSGEA 537
BLAST of hemicentin-1 isoform X2 vs. Ensembl Xenopus
Match: lrrc8c (leucine rich repeat containing 8 VRAC subunit C [Source:Xenbase;Acc:XB-GENE-5797483]) HSP 1 Score: 110.538 bits (275), Expect = 1.312e-23 Identity = 154/679 (22.68%), Postives = 272/679 (40.06%), Query Frame = 3 Query: 705 NRGFVMCTAI-----NDAGVLTKNTSLLNIKYKPKIKPFVPNTVNAMINQTIDLSCEVYANPAATIQWVIMQGLQIIDSSK----------------FIA-----KIRPDMDGPLICEAKNYLG---STKETVQLNVLRDPLIHIDSNYRVPKNSNYSINCRVTSNPPPEFIKWYKLSNM--TDSSAVLISDDAKLNFILIDRSSTGMYACVTQNIQISTTGKRKPANSEKTMFLTVTYKPKEPQILGNKIISIMKGEKFIIKCSTDRKSPGEPFPTLKWIDVE-----TKDIVSDMETFQVINSESRHNGKYKCLAENEIGKSFSRETALVTVNEAPSIITQHKNRKVFLSYSDLPQSISFTCEFRGQPLYEARW-RYGNEKIPPSSQDFKIEDHRNISNERISQIFTKLTIDLYSRTFSQQTSLRSSPNGRYNCEADNRHGIASLDYFLXXXXXXXXXXNIRHRKIAASLNQNV-----VMIRCQAESISTMHIKWYKTNEHIVLPFQSKKYSIFEAEVTKYEPERDLFTPGLKVNELTIKDLENDDFSNYSCVASNDQGIKKVNFEVVFKSQ-----------------PDPPYDLRVTDFEWDSVTINWKPGFNGGLT-QNYEILVISENFGTQNVPFYSDKNENTLTITGLYPSTPYEIRIYAVNSIGRSLNSE 2561 +RG TA+ +D ++ + L + P+I P+ + + L+C+ P TI+W +G +++ K F+ KIRPD +G +C A+NYLG S ++++ +LRD S+ V + C+ P I W K D + KL +S G Y CV N+ G+R+ +E LTV +P + N +++ +F KC ++ G+P PT++W + ++ + D T ++ + G Y C+AEN +GK+ + +A++TV E P+ + + +++ V L ++++F CE G P W + G++ + F + ++ S +SQ LTI T+++ S G Y C+ N G + FL + + R+ +NQ V +++ C A I I W K + I++P Q + ++ L I+ + D Y+C AS G + N+ + Q P P VTD ++VT++W+P N G T +Y I S G+ + ++ + L P+ Y + AVN+ G S S+ Sbjct: 31 DRGLDSGTALPTSDHDDNSLVYTGSRLRQEDFPPRIVEH-PSDLIVSKGEPATLNCKAEGRPTPTIEW--YKGGDKVETDKDDPRSHRMLLPSGSLFFLRIVHGRKIRPD-EGVYVCVARNYLGEAVSHNASLEVAILRDDFRQNPSDVMVAVGEPAVMECQPPRGHPEPTISWKKDGTPIDDDKDERITIRGGKLMITYTRKSDAGKYVCVGTNM----VGERESEVAE----LTVLERPSFVRRPSNMAVTVDDSVEF--KC----EARGDPVPTVRWRKDDGDLPKSRYEIRDDHTLKIRKVTAGDMGSYTCVAENMVGKAEA--SAVLTVQEPPNFVVKPRDQVVALG-----RTVTFQCEATGNPQPAIFWQKEGSQNL-----LFSYQPPQSSSRFSVSQT-GDLTI----------TTVQKSDVGYYICQTLNVAGSITTKAFLEVTDVVADRPPPVIRQ--GPVNQTVAVDGTLIMNCIASGIPVPTIHWRK--DGILIPTQDSRIKQQDS------------------GALQIRYAKLSDTGRYTCTASTTSG--EANWSAYIEVQEFGVPVQPPRATDPNLIPSAPSKPEVTDVSKNTVTLSWQPNLNSGATPTSYLIEAFSHASGSSWQTVAENVKTDSFAVKALKPNAIYLFLVRAVNAYGLSDPSQ 644 HSP 2 Score: 64.3142 bits (155), Expect = 1.755e-9 Identity = 96/429 (22.38%), Postives = 152/429 (35.43%), Query Frame = 3 Query: 390 NSGYYVC--RVTLLTTSEHIISLAVVTVKTPPKSISFHFNKSINVFQEQEFIAIQCSVSGGIPPPKISM----YIVKDNAIKRLKIISSNFPNSTIAEVSAISLWRPHYLENRGFVMCTAINDAGVLTKNTSLLNIKYKPKIKPFV--PNTVNAMINQTIDLSCEVYANPAATIQWVIMQG------LQIIDSSKF-IAKIRPDMDGPLICEAKNYLGSTKETVQLNVLRDP-LIHIDSNYRVPKNSNYSINCRVTSNPPPEFIKWYKLSNMT---------DSSAVLISDDAKLNFILIDRSSTGMYACVTQNIQISTTGKRKPANSEKTMFLTVT--YKPKEPQILGNKII--SIMKGEKFIIKCSTDRKSPGEPFPTLKW----IDVETKDI---VSDMETFQVINSESRHNGKYKCLAENEIGKS 1568 + G YVC R L H SL V ++ F N S + E ++C G P P IS + D+ +R+ I I+ R + G +C N G + L + +P FV P+ + ++ +++ CE +P T++W G +I D I K+ G C A+N +G + + L V P + + V + C T NP P I W K + SS +S L + +S G Y C T N+ S T K FL VT + P ++ + ++ I+ C G P PT+ W I + T+D D Q+ ++ G+Y C A G++ Sbjct: 137 DEGVYVCVARNYLGEAVSHNASLEVAILRD-----DFRQNPSDVMVAVGEPAVMECQPPRGHPEPTISWKKDGTPIDDDKDERITIRGGKL---------MITYTR---KSDAGKYVCVGTNMVGERESEVAELTVLERPS---FVRRPSNMAVTVDDSVEFKCEARGDPVPTVRWRKDDGDLPKSRYEIRDDHTLKIRKVTAGDMGSYTCVAENMVGKAEASAVLTVQEPPNFVVKPRDQVVALGRTVTFQCEATGNPQPA-IFWQKEGSQNLLFSYQPPQSSSRFSVSQTGDLTITTVQKSDVGYYICQTLNVAGSITTK---------AFLEVTDVVADRPPPVIRQGPVNQTVAVDGTLIMNCIAS----GIPVPTIHWRKDGILIPTQDSRIKQQDSGALQIRYAKLSDTGRYTCTASTTSGEA 531
BLAST of hemicentin-1 isoform X2 vs. Ensembl Mouse
Match: Robo1 (roundabout guidance receptor 1 [Source:MGI Symbol;Acc:MGI:1274781]) HSP 1 Score: 107.457 bits (267), Expect = 9.081e-23 Identity = 148/617 (23.99%), Postives = 246/617 (39.87%), Query Frame = 3 Query: 849 LSCEVYANPAATIQWVIMQGLQIIDSSK---------------FIAKI------RPDMDGPLICEAKNYLG---STKETVQLNVLRDPLIHIDSNYRVPKNSNYSINCRVTSNPPPEFIKWYK-LSNMTDSSAVLISDDAKLNFILIDRSSTGMYACVTQNIQISTTGKRKPANSEKTMFLTVTYKPKEPQILGNKIISIMKGEKFIIKCSTDRKSPGEPFPTLKWI--DVE---TKDIVSDMETFQVINSESRHNGKYKCLAENEIGKSFSRETALVTVNEAPSIITQHKNRKVFLSYSDLPQSISFTCEFRGQPLYEARWRY-GNEKIPPSSQDFKIEDHRNISNERISQIFTKLTIDLYSRTFSQQTSLRSSPNGRYNCEADNRHGIASLDYFLXXXXXXXXXXNIRHRKIAASLNQNV-----VMIRCQAESISTMHIKWYKTNEHIVLPFQSKKYSIFEAEVTKYEPERDLFTPGLKVNELTIKDLENDDFSNYSCVASNDQG-------IKKVNFEVVFKSQ--------PDPPYDLRVTDFEWDSVTINWKPGFNGGLT-QNYEILVISENFGTQNVPFYSDKNENTLTITGLYPSTPYEIRIYAVNSIG 2543 L+C+ P TI+W +G + +++ K F +I RPD +G IC A+NYLG S ++++ +LRD S+ V + C+ P I W K S + D + KL +S G Y CV N+ G+R+ +E LTV +P + N +++ +F KC ++ G+P PT++W D E ++ + D T ++ + G Y C+AEN +GK + +A +TV E P + + +++ V L ++++F CE G P WR G++ + F + ++ S +SQ LTI T+++ S G Y C+ N G +L + + R+ +NQ V +++ C A I W K + +++ Q + E+ V L I+ + D Y+C AS G I+ F V + P P VTD ++VT++W+P N G T +Y I S G+ + T I GL P+ Y + A N+ G Sbjct: 48 LNCKAEGRPTPTIEW--YKGGERVETDKDDPRSHRMLLPSGSLFFLRIVHGRKSRPD-EGVYICVARNYLGEAVSHNASLEVAILRDDFRQNPSDVMVAVGEPAVMECQPPRGHPEPTISWKKDGSPLDDKDERITIRGGKLMITYTRKSDAGKYVCVGTNM----VGERESEVAE----LTVLERPSFVKRPSNLAVTVDDSAEF--KC----EARGDPVPTVRWRKDDGELPKSRYEIRDDHTLKIRKVTAGDMGSYTCVAENMVGK--AEASATLTVQEPPHFVVKPRDQVVALG-----RTVTFQCEATGNPQPAIFWRREGSQNL-----LFSYQPPQSSSRFSVSQT-GDLTI----------TNVQRSDVGYYICQTLNVAGSIITKAYLEVTDVIADRPPPVIRQ--GPVNQTVAVDGTLILSCVATGSPAPTILWRK--DGVLVSTQDSRIKQLESGV------------------LQIRYAKLGDTGRYTCTASTPSGEATWSAYIEVQEFGVPVQPPRPTDPNLIPSAPSKPEVTDVSKNTVTLSWQPNLNSGATPTSYIIEAFSHASGSSWQTAAENVKTETFAIKGLKPNAIYLFLVRAANAYG 602 HSP 2 Score: 76.6406 bits (187), Expect = 2.022e-13 Identity = 100/450 (22.22%), Postives = 165/450 (36.67%), Query Frame = 3 Query: 1041 LIHIDSNYRVPKNSNYSINCRVTSNPPPEFIKWYKLSNMTDS------SAVLISDDAKLNFILI-----DRSSTGMYACVTQNIQISTTGKRKPANSEKTMFLTVTYKPKEPQILGNKIISIMKGEKFIIKCSTDRKSPGEPFPTLKW------IDVETKDIVSDMETFQVINSESRHNGKYKCLAENEIGKSFSRETALVTVNEAPSIITQHKNRKVFLSYSDLPQSISFTCEFRGQPLYEARWRYGNEKIPPSSQDFKIEDHRNISNERISQIFTKLTIDLYSRTFSQQTSLRSSPNGRYNCEADNRHGIASLDYFLXXXXXXXXXXNIRHRKIAASLNQNVVMIRCQAESISTMHIKWYKTNEHIVL-----PFQSKKYSIFEAEVTKYEPERDLFTPGLKVNELTIKDLENDDFSNYSCVASNDQG--IKKVNFEV--VFKSQPDP 2312 ++ S+ V K ++NC+ P P I+WYK ++ S ++ L F+ I R G+Y CV +N S + L ++ ++ + GE +++C R G P PT+ W +D + + I + + GKY C+ N +G+ S E A +TV E PS + + N V + S F CE RG P+ RWR + ++P S ++I D + +++ + G Y C A+N G A L ++ PP R + +A V +C+A I W + +L P S ++S+ + +LTI +++ D Y C N G I K EV V +P P Sbjct: 31 IVEHPSDLIVSKGEPATLNCKAEGRPTPT-IEWYKGGERVETDKDDPRSHRMLLPSGSLFFLRIVHGRKSRPDEGVYICVARNYLGEAVSHNA---SLEVAILRDDFRQNPSDVM------VAVGEPAVMECQPPR---GHPEPTISWKKDGSPLDDKDERITIRGGKLMITYTRKSDAGKYVCVGTNMVGERES-EVAELTVLERPSFVKRPSNLAVTVD-----DSAEFKCEARGDPVPTVRWRKDDGELPKSR--YEIRDDHTLKIRKVT----------------------AGDMGSYTCVAENMVGKAEASATLTVQEPPHFVVKPRDQVVALG---RTVTFQCEATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSVSQ------------------TGDLTITNVQRSDVGYYICQTLNVAGSIITKAYLEVTDVIADRPPP 416 HSP 3 Score: 58.5362 bits (140), Expect = 6.839e-8 Identity = 97/434 (22.35%), Postives = 155/434 (35.71%), Query Frame = 3 Query: 360 RLTIHNISSDNSGYYVC--RVTLLTTSEHIISLAVVTVKTPPKSISFHFNKSINVFQEQEFIAIQCSVSGGIPPPKISMYIVK---DNAIKRLKIISSNFPNSTIAEVSAISLWRPHYLENRGFVMCTAINDAGVLTKNTSLLNIKYKPKIKPFV--PNTVNAMINQTIDLSCEVYANPAATIQWVIMQG------LQIIDSSKF-IAKIRPDMDGPLICEAKNYLGSTKETVQLNVLRDPLIHIDSNYRVPK-NSNYSINCRVTSNPPPEFIKWYKLSNMT---------DSSAVLISDDAKLNFILIDRSSTGMYACVTQNIQISTTGKRKPANSEKTMFLTVTYKPKEPQILGNKIISIMKGEKFIIKCSTDRKSPGEPFPTLKW----IDVETKDI-VSDMET--FQVINSESRHNGKYKCLAENEIGKS 1568 R+ S + G Y+C R L H SL V ++ F N S + E ++C G P P IS D+ +R+ I I+ R + G +C N G + L + +P FV P+ + ++ + + CE +P T++W G +I D I K+ G C A+N +G + + L V P + +V + C T NP P I W + + SS +S L + RS G Y C T N+ S K A E T + P Q N+ +++ I+ C G P PT+ W + V T+D + +E+ Q+ ++ G+Y C A G++ Sbjct: 92 RIVHGRKSRPDEGVYICVARNYLGEAVSHNASLEVAILRD-----DFRQNPSDVMVAVGEPAVMECQPPRGHPEPTISWKKDGSPLDDKDERITIRGGKL---------MITYTR---KSDAGKYVCVGTNMVGERESEVAELTVLERPS---FVKRPSNLAVTVDDSAEFKCEARGDPVPTVRWRKDDGELPKSRYEIRDDHTLKIRKVTAGDMGSYTCVAENMVGKAEASATLTVQEPPHFVVKPRDQVVALGRTVTFQCEATGNPQPA-IFWRREGSQNLLFSYQPPQSSSRFSVSQTGDLTITNVQRSDVGYYICQTLNVAGSIITK---AYLEVTDVIADRPPPVIRQGPVNQTVAV--DGTLILSCVAT----GSPAPTILWRKDGVLVSTQDSRIKQLESGVLQIRYAKLGDTGRYTCTASTPSGEA 495
BLAST of hemicentin-1 isoform X2 vs. Ensembl Mouse
Match: Robo1 (roundabout guidance receptor 1 [Source:MGI Symbol;Acc:MGI:1274781]) HSP 1 Score: 106.301 bits (264), Expect = 1.777e-22 Identity = 148/617 (23.99%), Postives = 246/617 (39.87%), Query Frame = 3 Query: 849 LSCEVYANPAATIQWVIMQGLQIIDSSK---------------FIAKI------RPDMDGPLICEAKNYLG---STKETVQLNVLRDPLIHIDSNYRVPKNSNYSINCRVTSNPPPEFIKWYK-LSNMTDSSAVLISDDAKLNFILIDRSSTGMYACVTQNIQISTTGKRKPANSEKTMFLTVTYKPKEPQILGNKIISIMKGEKFIIKCSTDRKSPGEPFPTLKWI--DVE---TKDIVSDMETFQVINSESRHNGKYKCLAENEIGKSFSRETALVTVNEAPSIITQHKNRKVFLSYSDLPQSISFTCEFRGQPLYEARWRY-GNEKIPPSSQDFKIEDHRNISNERISQIFTKLTIDLYSRTFSQQTSLRSSPNGRYNCEADNRHGIASLDYFLXXXXXXXXXXNIRHRKIAASLNQNV-----VMIRCQAESISTMHIKWYKTNEHIVLPFQSKKYSIFEAEVTKYEPERDLFTPGLKVNELTIKDLENDDFSNYSCVASNDQG-------IKKVNFEVVFKSQ--------PDPPYDLRVTDFEWDSVTINWKPGFNGGLT-QNYEILVISENFGTQNVPFYSDKNENTLTITGLYPSTPYEIRIYAVNSIG 2543 L+C+ P TI+W +G + +++ K F +I RPD +G IC A+NYLG S ++++ +LRD S+ V + C+ P I W K S + D + KL +S G Y CV N+ G+R+ +E LTV +P + N +++ +F KC ++ G+P PT++W D E ++ + D T ++ + G Y C+AEN +GK + +A +TV E P + + +++ V L ++++F CE G P WR G++ + F + ++ S +SQ LTI T+++ S G Y C+ N G +L + + R+ +NQ V +++ C A I W K + +++ Q + E+ V L I+ + D Y+C AS G I+ F V + P P VTD ++VT++W+P N G T +Y I S G+ + T I GL P+ Y + A N+ G Sbjct: 58 LNCKAEGRPTPTIEW--YKGGERVETDKDDPRSHRMLLPSGSLFFLRIVHGRKSRPD-EGVYICVARNYLGEAVSHNASLEVAILRDDFRQNPSDVMVAVGEPAVMECQPPRGHPEPTISWKKDGSPLDDKDERITIRGGKLMITYTRKSDAGKYVCVGTNM----VGERESEVAE----LTVLERPSFVKRPSNLAVTVDDSAEF--KC----EARGDPVPTVRWRKDDGELPKSRYEIRDDHTLKIRKVTAGDMGSYTCVAENMVGK--AEASATLTVQEPPHFVVKPRDQVVALG-----RTVTFQCEATGNPQPAIFWRREGSQNL-----LFSYQPPQSSSRFSVSQT-GDLTI----------TNVQRSDVGYYICQTLNVAGSIITKAYLEVTDVIADRPPPVIRQ--GPVNQTVAVDGTLILSCVATGSPAPTILWRK--DGVLVSTQDSRIKQLESGV------------------LQIRYAKLGDTGRYTCTASTPSGEATWSAYIEVQEFGVPVQPPRPTDPNLIPSAPSKPEVTDVSKNTVTLSWQPNLNSGATPTSYIIEAFSHASGSSWQTAAENVKTETFAIKGLKPNAIYLFLVRAANAYG 612 HSP 2 Score: 77.7962 bits (190), Expect = 9.466e-14 Identity = 105/468 (22.44%), Postives = 172/468 (36.75%), Query Frame = 3 Query: 987 NYLGSTKETVQLNVLRDPLIHIDSNYRVPKNSNYSINCRVTSNPPPEFIKWYKLSNMTDS------SAVLISDDAKLNFILI-----DRSSTGMYACVTQNIQISTTGKRKPANSEKTMFLTVTYKPKEPQILGNKIISIMKGEKFIIKCSTDRKSPGEPFPTLKW------IDVETKDIVSDMETFQVINSESRHNGKYKCLAENEIGKSFSRETALVTVNEAPSIITQHKNRKVFLSYSDLPQSISFTCEFRGQPLYEARWRYGNEKIPPSSQDFKIEDHRNISNERISQIFTKLTIDLYSRTFSQQTSLRSSPNGRYNCEADNRHGIASLDYFLXXXXXXXXXXNIRHRKIAASLNQNVVMIRCQAESISTMHIKWYKTNEHIVL-----PFQSKKYSIFEAEVTKYEPERDLFTPGLKVNELTIKDLENDDFSNYSCVASNDQG--IKKVNFEV--VFKSQPDP 2312 N LG T ++ ++ S+ V K ++NC+ P P I+WYK ++ S ++ L F+ I R G+Y CV +N S + L ++ ++ + GE +++C R G P PT+ W +D + + I + + GKY C+ N +G+ S E A +TV E PS + + N V + S F CE RG P+ RWR + ++P S ++I D + +++ D+ G Y C A+N G A L ++ PP R + +A V +C+A I W + +L P S ++S+ + +LTI +++ D Y C N G I K EV V +P P Sbjct: 23 NSLGYTGSRLRQEDFPPRIVEHPSDLIVSKGEPATLNCKAEGRPTPT-IEWYKGGERVETDKDDPRSHRMLLPSGSLFFLRIVHGRKSRPDEGVYICVARNYLGEAVSHNA---SLEVAILRDDFRQNPSDVM------VAVGEPAVMECQPPR---GHPEPTISWKKDGSPLDDKDERITIRGGKLMITYTRKSDAGKYVCVGTNMVGERES-EVAELTVLERPSFVKRPSNLAVTVD-----DSAEFKCEARGDPVPTVRWRKDDGELPKSR--YEIRDDHTLKIRKVT------AGDM----------------GSYTCVAENMVGKAEASATLTVQEPPHFVVKPRDQVVALG---RTVTFQCEATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSVSQ------------------TGDLTITNVQRSDVGYYICQTLNVAGSIITKAYLEVTDVIADRPPP 426 HSP 3 Score: 58.151 bits (139), Expect = 8.746e-8 Identity = 97/434 (22.35%), Postives = 155/434 (35.71%), Query Frame = 3 Query: 360 RLTIHNISSDNSGYYVC--RVTLLTTSEHIISLAVVTVKTPPKSISFHFNKSINVFQEQEFIAIQCSVSGGIPPPKISMYIVK---DNAIKRLKIISSNFPNSTIAEVSAISLWRPHYLENRGFVMCTAINDAGVLTKNTSLLNIKYKPKIKPFV--PNTVNAMINQTIDLSCEVYANPAATIQWVIMQG------LQIIDSSKF-IAKIRPDMDGPLICEAKNYLGSTKETVQLNVLRDPLIHIDSNYRVPK-NSNYSINCRVTSNPPPEFIKWYKLSNMT---------DSSAVLISDDAKLNFILIDRSSTGMYACVTQNIQISTTGKRKPANSEKTMFLTVTYKPKEPQILGNKIISIMKGEKFIIKCSTDRKSPGEPFPTLKW----IDVETKDI-VSDMET--FQVINSESRHNGKYKCLAENEIGKS 1568 R+ S + G Y+C R L H SL V ++ F N S + E ++C G P P IS D+ +R+ I I+ R + G +C N G + L + +P FV P+ + ++ + + CE +P T++W G +I D I K+ G C A+N +G + + L V P + +V + C T NP P I W + + SS +S L + RS G Y C T N+ S K A E T + P Q N+ +++ I+ C G P PT+ W + V T+D + +E+ Q+ ++ G+Y C A G++ Sbjct: 102 RIVHGRKSRPDEGVYICVARNYLGEAVSHNASLEVAILRD-----DFRQNPSDVMVAVGEPAVMECQPPRGHPEPTISWKKDGSPLDDKDERITIRGGKL---------MITYTR---KSDAGKYVCVGTNMVGERESEVAELTVLERPS---FVKRPSNLAVTVDDSAEFKCEARGDPVPTVRWRKDDGELPKSRYEIRDDHTLKIRKVTAGDMGSYTCVAENMVGKAEASATLTVQEPPHFVVKPRDQVVALGRTVTFQCEATGNPQPA-IFWRREGSQNLLFSYQPPQSSSRFSVSQTGDLTITNVQRSDVGYYICQTLNVAGSIITK---AYLEVTDVIADRPPPVIRQGPVNQTVAVDG--TLILSCVAT----GSPAPTILWRKDGVLVSTQDSRIKQLESGVLQIRYAKLGDTGRYTCTASTPSGEA 505
BLAST of hemicentin-1 isoform X2 vs. Ensembl Mouse
Match: Hmcn1 (hemicentin 1 [Source:MGI Symbol;Acc:MGI:2685047]) HSP 1 Score: 103.219 bits (256), Expect = 1.861e-21 Identity = 168/689 (24.38%), Postives = 265/689 (38.46%), Query Frame = 3 Query: 363 LTIHNISSDNSGYYVCRVTLLTTSEHIISLAVVTVKTPPKSIS-FHFNKSINVFQEQEFIAIQCSVSGGIPPPKISMYIVKDNAIKRLKIISSNFPNSTIAEVSA---ISLWRPHYLENRGFVMCTAINDAGVLTKNTSLLNIKYKPKIKPFVPNT---VNAMINQTIDLSCEVYANPAATIQWVIMQGLQIIDSSKF----------IAKIRPDMDGPLICEAKNYLGSTKETVQLNVLRDPLIHI-DSNYRVPKNSN-YSINCRVTSNPPPEFIKWYK----LSNMTDSSAVLISDDAKLNFILIDRSSTGMYACVTQNIQISTTGKRKPANSEKTMFLTVTYKPKEPQILGNKI---ISIMKGEKFIIKCSTDRKSPGEPFPTLKWI---------DVETKDIVSDMETFQVINSESRHNGKYKCLAENEIGKSFSRETALVTVN--EAPSIITQHKNRKVFLSYSDLPQSISFTCEFRGQPLYEARWRYGNEKIPPSSQDFKIEDHRNISNERISQIFTKLTIDLYSRTFSQQTSLRSSPNGRYNCEADNRHGIASLDYFLXXXXXXXXXXNIRHRKIAASLNQNVVMIRCQAESISTMHIKWYKTNEHIVLPFQSKKYSIFEAEVTKYEPERDLFTPGLKVNELTIKDLENDDFSNYSCVASNDQGIKKVNFEVVFKSQPDPPY 2318 L I N ++G YVC T+ + V PP I H + S+ V FI++ C VS G PPP +S ++ + IK PN+ + V + + R + + G C AIN AG K S L + P IK + VN ++ L CE A P I W G I DS+ I + G +C A N G + LNV P I ++ V SN ++ C T PPP I W K + N ++S +KL RS++G Y CV N++ GK A +F+ V P + G ++ +S++ GE + C+ D G P P L+W+ + E + +D T + + + GKY C+A N G+ E + +N P I + + ++ D SI+ C+ G P + W +P SS R +S ++ +I D+ Y C A NR G+ S Y L + PP + + +I + M C + + W + + + +A +T + T G+ L + E +D Y+CVA+N+ G +V+ V K +PP+ Sbjct: 2927 LQILNAQITDTGRYVCVAE--NTAGSAKKYFNLNVHVPPSVIGPNHEHLSVVV---NHFISLNCEVS-GFPPPDLS-WLKNEEPIK---------PNTNVLTVPGGRTLQIIRAK-ISDGGDYTCIAINQAGESKKKVS-LTVHVPPSIKDHGSQSLSIVNVREGTSVSLECESNAVPPPVITWS-KNGRMIPDSTNVEILTGGQTLHIRRAEVSDTGQYVCRAINVAGRDDKNFHLNVYVPPTIEGPETEVIVETISNPVTLTCDATGIPPPT-ITWLKNHKPIENSDPLEVHILSGGSKLQIARPQRSNSGNYTCVASNME----GK---AQKNFILFIQV-----PPSVAGAEVPSEVSVLLGENVELVCNAD----GIPTPHLQWLRDGKPIVNGETERVRVTTDGSTLNIYRALTSDMGKYTCVATNPAGE----EDRIFNLNVYVPPKIRGNKEEAEKLMALVD--TSINIECKATGTPPPQINWLKNGLPLPISSH------IRLLSAGQVVRIVRAQVSDI----------------AVYTCVASNRAGVDSKHYSLQVFVPPNMDNAMGTEEITIVKGSSTSMT-CFTDGTPAPSMSWLRDGQPLAP----------DAHLT-------VSTQGMV---LQLIKAETEDTGKYTCVATNEAG--EVSKHFVLKVL-EPPH 3527 HSP 2 Score: 103.219 bits (256), Expect = 2.221e-21 Identity = 154/697 (22.09%), Postives = 258/697 (37.02%), Query Frame = 3 Query: 315 VVPDSESQITISHESRLTIHNISSDNSGYYVCRVTLLTTSE----HIISLAVVTVKTPPKSISFHFNKSINVFQEQEFIAIQCSVSGGIPPPKISMYIVKDNAIKRLKIISSNFPNST--IAEVSAISLWRPHYLENRGFVMCTAINDAGVLTKNTSLLNIKYKPKIKPF-VPNTVNAMINQTIDLSCEVYANPAATIQWVIMQGLQIIDSSKFIAKIRPDMD------------GPLICEAKNYLGSTKETVQLNVLRDPLIHID----SNYRVPKNSNYSINCRVTSNPPPEFIKWYK--LSNMTDSSAVLISDDAKLNFILIDRSSTGMYACVTQNIQISTTGKRKPANSEKTMFLTVTYKPKEPQILGNKIISIMKGEKFIIKCSTDRKSPGEPFPTLKWIDVETKDIVSDME--------TFQVINSESRHNGKYKCLAENEIGKSFSRETALVTVNEAPSIITQHKNRKVFLSYSDLPQSISFTCEFRGQPLYEARWRYGNEKIPPSSQDFKIEDHRNISNERISQIFTKLTIDLYSRTFSQQTSLRSSPNGRYNCEADNRHGIASLDYFLXXXXXXXXXXNIRHRKIAASLNQNVVMIRCQAESISTMHIKWYKTNEHIVLPFQSKKYSIFEAEVTKYEPERDLFTPGLKVNELTIKDLENDDFSNYSCVASNDQGIKKVNFEVVFKSQP 2306 ++PDS + ++ L I ++G YVCR + + H+ T++ P + V + + C +G IPPP I+ +K K I ++ P ++ S + + RP N G C A N G KN +L I+ P + VP+ V+ ++ + ++L C P +QW + G I++ ++ D G C A N G LNV P I + +++ +I C+ T PPP+ I W K L S L+S + + S +Y CV N + K L V P +G + I+I+KG + C TD G P P++ W+ + + + D Q+I +E+ GKY C+A NE G+ S+ L V E P I +V + ++ + +C G P + W ++D R + T+ L + +S + GRY C A + G +Y + + PP I + N+ V + C+++++ I W K E + + P + + G L I + + D +NY+CVASN G F + P Sbjct: 3098 MIPDSTNVEILTGGQTLHIRRAEVSDTGQYVCRAINVAGRDDKNFHLNVYVPPTIEGP--------ETEVIVETISNPVTLTCDATG-IPPPTITW-------LKNHKPIENSDPLEVHILSGGSKLQIARPQR-SNSGNYTCVASNMEGKAQKNF-ILFIQVPPSVAGAEVPSEVSVLLGENVELVCNADGIPTPHLQW-LRDGKPIVNGETERVRVTTDGSTLNIYRALTSDMGKYTCVATNPAGEEDRIFNLNVYVPPKIRGNKEEAEKLMALVDTSINIECKATGTPPPQ-INWLKNGLPLPISSHIRLLSAGQVVRIVRAQVSDIAVYTCVASN---------RAGVDSKHYSLQVFVPPNMDNAMGTEEITIVKGSSTSMTCFTD----GTPAPSMSWLR-DGQPLAPDAHLTVSTQGMVLQLIKAETEDTGKYTCVATNEAGE-VSKHFVL-KVLEPPHINGSEGPGEVSVIVNN---PLELSCIASGIPAPKISW---------------MKDGRPF-------LQTEQVQTLEGGAILRVSSAQVEDTGRYTCLASSPAGDDDKEYLVRVHVPPNIAGMDEAQDFTVLRNRQVTL-ECKSDAVPPPVIMWLKNREQL-----------------QATPRVRILSGG---RYLQINNADLGDTANYTCVASNIAGKTTREFNLTVNVPP 3712 HSP 3 Score: 99.7525 bits (247), Expect = 2.413e-20 Identity = 151/698 (21.63%), Postives = 266/698 (38.11%), Query Frame = 3 Query: 315 VVPDSESQITI-SHESRLTIHNISSDNSGYYVC---RVTLLTTSEHIISLAVVTVKTPPKSISFHFNKSINVFQEQEFIAIQCSVSGGIPPPKISMYIVKDNAIKRLKIISSNFPNSTIAEVSAISLWRPHYLENRGFVMCTAINDAGVLTKNTSLLNIKYKPKI--KPFVPNTVNAMINQTIDLSCEVYANPAATIQWV-------IMQGLQIIDSSKFI--AKIRPDMDGPLICEAKNYLGSTKETVQLNVLRDPLIHIDS---NYRVPKNSNYSINCRVTSNPPPEFIKWYKLSNM--TDSSAVLISDDAKLNFILIDRSSTGMYACVTQNIQISTTGKRKPANSEKTMFLTVTYKPKEPQILGNKIISIMKGEKFIIKCSTDRKSPGEPFPTLKWIDVETK-------DIVSDMETFQVINSESRHNGKYKCLAENEIGKSFSRETALVTVNEAPSIITQHKNRKVFLSYSDLP----QSISFTCEFRGQPLYEARWRYGNEKIPPSSQDFKIEDHRNISNERISQIFTKLTIDLYSRTFSQQTSLRSSPNGRYNCEADNRHGIASLDY---------FLXXXXXXXXXXNIRHRKIAASLNQNVVMIRCQAESISTMHIKWYKTNEHIVLPFQSKKYSIFEAEVTKYEPERDLFTPGLKVNELTIKDLENDDFSNYSCVASNDQGIKKVNFEV 2288 V+ DS ++ I S RL I ++G Y C V + E+ + + + P + S I V + + I+++C V G IP P ++ ++ + + K + I + I + ++ + G +C A+N AG+ K L ++ P I VP V+ + ++ L+CE P +I W+ + ++I+ + + + RP+ G C +N G ++ L+VL P I ++ + ++ + + ++ C V NP P+ I W+K + D + ++S L S TG Y C+ NI K + +F++ T + +I I+ ++ C P T+ W T I+ T Q++N++ + G+Y C+A NE G+ V + P II + LS ++ S++ CE P RW Q K +DH +TI T Q + S GRY C A N G LD+ F + + R + + N + + C+ + + WYK P S +R L PG +V L I + +D Y+CVA N+ G + ++V Sbjct: 2236 VLADSAGRVHILSGGRRLQISIAEKADAGLYTCVASNVAGVAKKEYNLQVYI----RPSITNSGGHRPEITVIRGKS-ISLECEVQG-IPQPTVT-WMKDGRPLTKGKGVE-------ILDEGRILQLKNVHVSDTGRYVCVAVNVAGMTDKRYDL-SVHAPPSIIGNHGVPENVSVVEKSSVSLTCEASGIPLPSITWLKDGWPVNLGSSVKILSGGRMLRLMQTRPEDAGQYTCIVRNAAGEDRKMFGLSVLVPPHIVGENTLEDVKIKEKQSVTLTCEVRGNPVPQ-ITWHKDGQLLQEDEAHHMMSGGRFLQITNAQVSHTGRYTCLASNI-----AGDKSKSFRLNVFVSPTIAGVDSDGSPEDVIVILNSPTSLV-CEAYSYPPA----TITWFKDGTPLESNRNIRILPGGRTLQILNAQEDNAGRYSCVATNEAGEKIKHYEVKVYI---PPIIKKGDLLGPGLSPKEVKIRVNSSLTLECEAYAIPSASLRWYK-------DGQPLKSDDH--------------VTIAASGHTL-QIKEAQISDTGRYTCVASNLAGEDELDFDVNIQVPPSFQKLWEIGNMLDTGRSGEAKDVIINNPLSLHCETNAAPPPTLTWYKDGR----PLTSS--------------DRVLILPGGRV--LQIPRAKVEDAGRYTCVAVNEAGEDSLRYDV 2862 HSP 4 Score: 93.5893 bits (231), Expect = 1.866e-18 Identity = 152/679 (22.39%), Postives = 265/679 (39.03%), Query Frame = 3 Query: 363 LTIHNISSDNSGYYVCRVTLLTTSEHIISLAVVTVKTPPKSISFHFNKSINVFQEQEFIAIQCSVSGGIPPPKISMYIVKDNAIKRL------KIISSNFPNSTIAEVSAISLWRPHYLENRGFVMCTAINDAGVLTKNTSLLNIKYKPKIKPFVPNTVNAMINQTIDLSCEVYANPAATIQWVIMQGLQIIDSSKFIA-----------KIRPDMDGPLICEAKNYLGSTKETVQLNVLRDPLIHI-DSNYRVPKNSNYSINCRVTSNPPPEFIKWYKLSN-MTDSSAVLISDDAKLNFILIDRSSTGMYACVTQNIQISTTGKRKPANSEKTMFLTVTYKPKEPQILGNKI-ISIMKGEKFIIKCSTDRKSPGEPFPTLKW-------IDVETKDIVSDMETFQVINSESRHNGKYKCLAENEIGKSFSRET----ALVTVNEAPSIITQHKNRKVFLSYSDLPQSISFTCEFRGQPLYEARWRYGNEKIPPSSQDFKIEDHRNISNERISQIFTKLTIDLYSRTFSQQTSLRSSPNGRYNCEADNRHGIASLDYFLXXXXXXXXXXNIRHRKIAASLNQNVVMIRCQAESISTMHIKWYKTNEHIVLPFQSKKYSIFEAEVTKYEPERDLFTPGLKVNELTIKDLENDDFSNYSCVASNDQGIKKVNFEVVFKSQP 2306 L I + S D++ Y C VT + + +TV+ PP +I+ ++ ++ ++ A+ + G+P P I N ++ L +I+SS AI + L + G C A N AG ++ +L ++ P I+P P+ ++ ++N I L CE P I W +G+ +I S K +A +R D G +C A+N G+ V+LNV P+I Y V + S+ C +PPP+ I W+K + +T+S I + L G Y C+ N+ +S + LTV P+ I ++ ++ + + ++ C D G P P + W ++ K + N +G Y C+A N G+ T L T E P ++ +K ++ LS C+ G PL + W + N IP + I H + E++S+ +G Y C A+N G F+ +K PP+ K + I L N ++ C+ + I+W + I + + ++ L L I N+D +Y+CVA+N+ G+ + + + +S P Sbjct: 3860 LVIISPSVDDTASYECTVT--SDAGEDKRAVDLTVQVPP-TIA---DEPMDFLVTRQAPAVMTCSASGVPVPSIHW---TKNGLRLLPRGDGYRILSSG----------AIEIPTTQ-LNHAGRYTCVARNAAGSAHRHVTL-RVQEPPVIQP-QPSELDVILNNPILLPCEATGIPTPFITWQ-KEGINVITSGKSLAILPSGSLQISRAVRGDA-GTYMCVAQNPAGTALGKVKLNVQVPPVISSHQKEYVVTMDKPVSLLCETEGSPPPD-ITWHKDGHALTESIRQRILNSGALQIAFAQPDDAGQYTCMAANMA---------GSSSVSSTLTVHVPPR---IQSTEVHFTVNENSQAVLPCVAD----GIPTPAIHWEKDGVLIANLLGKYTAQPYGELILENVVLEDSGTYTCVANNAAGEDTRIVTLAVHTLPTFTELPGDLSLNKGEQLRLS-----------CKAVGIPLPKLTWTFNNNIIP--AHFDSINGHSELVIEKVSK----------------------EDSGTYVCTAENSVGFVKAIGFVYVKEPPVFKGDYPSNWIEP-LGGNAIL-NCEVKGDPAPTIQWSRKGADIEISHRIRQ---------------------LGNGSLAIYGTVNEDAGDYTCVAANEAGMVERSMSLTLQSSP 4439 HSP 5 Score: 90.5077 bits (223), Expect = 1.351e-17 Identity = 130/553 (23.51%), Postives = 217/553 (39.24%), Query Frame = 3 Query: 699 LENRGFVMCTAINDAGVLTKNTSL---LNIKYKPKIKPF---VPNTVNAMINQTIDLSCEVYANPAATIQWVIMQGLQII---DSSKFIAKIRPDM--------DGPLICEAKNYLGSTKETVQLNVLRDPLIHIDSNYR---VPKNSNYSINCRVTSNPPPEFIKWYKLSN--MTDSSAVLISDDAKLNFILIDRSSTGMYACVTQNIQISTTGKRKPANSEKTMFLTVTYKP--KEPQILGNKIISIMKGEKFIIKCSTDRKSPGEPFPTLKWI-------DVETKDIVSDMETFQVINSESRHNGKYKCLAENEIGKSFSRETALVTVNEAPSIITQHKNRKVFLSYSDLPQSISFTCEFRGQPLYEARWRYGNEKIPPSSQDFKIEDHRNISNERISQIFTKLTIDLYSRTFSQQTSLRSSPNGRYNCEADNRHGIASLDYFLXXXXXXXXXXNIRHRKIAASLNQNVVMIRCQAESISTMHIKWYKTNEHIVLPFQSKKYSIFEAEVTKYEPERDLFTPGLKVNELTIKDLENDDFSNYSCVASNDQG 2264 +E+ G C A+N+AG SL +++ P IK +P V ++N++ + C NPA W + QI+ + KF + R G +C A+N GS K+ LNV P + I N+ V N S+NC V+ PPP+ + W K +++ + + L I S G Y C+ N + S+K + LTV P K+ I+++ +G ++C ++ P P + W D +I++ +T + +E G+Y C A N G+ V V P I + + + S+ ++ TC+ G P W +++H+ I N ++ L + Q + S +G Y C A N G A ++ L I+ PP + +++ L +NV ++ C A+ I T H++W + + IV E ER T + L I D Y+CVA+N G Sbjct: 2839 VEDAGRYTCVAVNEAG----EDSLRYDVHVLLPPVIKGANSDLPEEVTVLVNKSTQMECSSSGNPAPRNYW--QKDGQILLEDEHHKFQSDGRSLQILNAQITDTGRYVCVAENTAGSAKKYFNLNVHVPPSV-IGPNHEHLSVVVNHFISLNCEVSGFPPPD-LSWLKNEEPIKPNTNVLTVPGGRTLQIIRAKISDGGDYTCIAIN---------QAGESKKKVSLTVHVPPSIKDHGSQSLSIVNVREGTSVSLECESNAVPP----PVITWSKNGRMIPDSTNVEILTGGQTLHIRRAEVSDTGQYVCRAINVAGRDDKNFHLNVYV---PPTIEGPETEVIVETISN---PVTLTCDATGIPPPTITW---------------LKNHKPIENSDPLEVHI-----LSGGSKLQIARPQRSNSGNYTCVASNMEGKAQKNFILFIQVPPSVAGAEVPSEVSVLLGENVELV-CNADGIPTPHLQWLRDGKPIV----------------NGETERVRVT--TDGSTLNIYRALTSDMGKYTCVATNPAG 3325 HSP 6 Score: 90.1225 bits (222), Expect = 1.876e-17 Identity = 162/689 (23.51%), Postives = 254/689 (36.87%), Query Frame = 3 Query: 348 SHESRLTIHNISSDNSGYYVCRVTLLTTSEHIISLAVVTVKTPP--KSISFHFNKSINVFQEQEFIAIQCSVSGGIPPPKISMYIVKDNAIKRLKIISSNFPNSTIAEVSAISLWRPHYLENRGFVMCTAINDAGVLTKNTSLLNIKYKPKI--KPFVPNTVNAMINQTIDLSCEVYANPAATIQW-------VIMQGLQIIDSSKFIA--KIRPDMDGPLICEAKNYLGSTKETVQLNVLRDPLI---HIDSNYRVPKNSNYSINCRVTSNPPPEFIKWYKLSN---MTDSSAVLISDDAKLNFILIDRSSTGMYACVTQNIQISTTGKRKPANSEKTMFLTVTYKPKEPQILGNKI---ISIMKGEKFIIKCSTDRKSPGEPFPTLKWIDVETKDIVSDMETFQVINSESRH--------NGKYKCLAENEIG---KSFSRETALVTVNEAPSI---ITQHKNRKVFLSYSDLPQSISFTCEFRGQPLYEARWRYGNEKIPPSSQDFKIEDHRNISNERISQIFTKLTIDLYSRTFSQQTSLRSSPNGRYNCEADNRHGIASLDYFLXXXXXXXXXXNIRHRKIAASLNQNVVMIRCQAESISTMHIKWYKTNEHIVLPFQSKKYSIFEAEVTKYEPERDLFTPGLKVNELTIKDLENDDFSNYSCVASNDQGIKKVNFEVVFKSQP 2306 S + L+I ++G Y C T + S+ + + V+ PP + + FN + I C G P P I + + ++ P +I E A+ + N G +C A+N+AG T+ L + P I K V N V+ + +Q L CEV P+ I W +QI+++ K + K+ + G C+A N G++++ +NVL P I S V N N ++ C T P P I W+K + D + L L+ RS G Y C N GK+ K + LTV Y P P I G I IS + ++C T G P P + W + + + S + + + H + Y C A N G KSF V + P+I +T N++V + QS+ C+ G P W + +P + D H +++ +I + L +D G+Y C A + G + Y + + PP ++ L N++ + CQ I W K + I ERD F L +L I + D Y CVA+N G + FEV P Sbjct: 1220 SPDGTLSIEQAVISDAGVYTCAATNIAGSDE--AEVTLHVQEPPSVEDLQPPFNTPFQERLANQRIEFPCPAKG-TPKPTIKW-------LHNGREVTGQEPGVSILEDGALLVIASVTPHNNGEYICVAVNEAGT-TERKYNLKVHVPPVIRDKEHVTN-VSVLTSQLASLYCEVEGTPSPVITWYKDDIQVTESSTVQIVNNGKILKLFKVSAEDAGRYSCKAINIAGTSQKDFSVNVLVPPSILGASSPSEVSVVLNHNVTLQCPGTGVPFPA-IHWFKDGKPLFLGDPNIELSDRGQSLHLRNARRSDKGRYQCTVSN----AAGKQA-----KDIKLTV-YVP--PSIKGGNITTEISALLNSIVKLECETR----GLPVPAITWYK-DGQVVTSSSQALYIDKGQLLHIQRAQVSDSATYTCHAANVAGTAEKSFH-----VDIYVPPTIEGDLTAPSNKQVIIG-----QSLILECKAAGNPPPILTWL--KDGVPVKASD---NIHIEAGGKKL-EILSALEVD----------------RGQYICVATSVAGEREIKYEVDVLVPPAVEGG-EETSYFIVLANNLLELDCQVSGSPPPTIMWLKGGQLI--------------------DERDGFKILLNGRKLVIAQAQVSDTGLYQCVATNIAGDHRKEFEVTVHVPP 1825 HSP 7 Score: 77.7962 bits (190), Expect = 1.174e-13 Identity = 175/741 (23.62%), Postives = 279/741 (37.65%), Query Frame = 3 Query: 159 PNNATVNSKENLTLEC-VVDQQNIVYSWEYKPFHIKSNIMSKVLGFCYFEKPCVVPDSESQITISHESRLTIHNISSDNSGYYVCRVTLLTTSEHIISLAVV--TVKTPPKSISFHFNKSINVFQEQEFIAIQCSVSGGIPPPKI-----SMYIVKDNAIKRLKIISSNFPNSTIAEVSAISLWRPHYLENRGFVMCTAINDAGVLTKNTSLLNIKYKPKIKPFVPNTVNAMINQTIDLSCEVYANPAATIQWVIMQGLQIIDSSKFIA--------KIRPDMD---GPLICEAKNYLGSTKETVQLNVLRDPL-IHIDSNYRVPKNSNYSINCRVTSNPPPEFIKWYKLSNMTDSS---AVLISDDAKLNFILIDR---SSTGMYACVTQNIQISTTGKRKPANSEKTMFLTVTYKPKEPQILG--NKIISIMKGEKFIIKCSTDRKSPGEPFPTLKWIDVETKDI------VSDMETFQVINSESRHNGKYKCLAENEIGKSFSRETALVTVNEAPSIITQHKNRKVFLSYSDLPQSISFTCEFRGQPLYEARWRYGNEKIPPSSQDFKIEDHRNISNERISQIFTKLTIDLYSRTFSQQTSLRSSPNGRYNCEADNRHGIASLDYFLXXXXXXXXXXNIRH----RKIAAS-LNQNVVMIRCQAESISTMHIKWYKTNEHIVLPFQSKKYSIFEAEVTKYEPERDLFTPGLKVNELTIKDLENDDFSNYSCVASNDQG 2264 PNN TV E L C V+ + +W+ I+ + DS T+++ S L + ++ ++G Y C V +SE + A V TV+ PK N+S F I+I CS + G P PKI M+I+ + R ++ S T+ +A+ ++ G C A N AG K TS L PK+ + A+ + T+ + C+ P ++W +G + S F++ KI+ D G C A N G + L+V P+ I S+ V SN ++ C V P P+ IKW +L NM S +V + + I S G Y C +N GK + S+ T+ +T P ++G + S+++G+ + C+ G P P +W+ + V + + + GKY C+A N G + +T V V+ PSI QH +++ + +P ++ C G P W E I SS F + LY S S +G Y C A N G A L + P + + R + + S L ++ C+A+S+ I W K + ++ PF R F P + I + D Y CVA+N G Sbjct: 526 PNNVTVTPGERAVLACLVISAVDYNLTWQRSGRDIR------------------LADSARIRTLANLS-LELRSVKIGDAGEYRCVV----SSEGGSAAASVFLTVQEKPKVTVMPKNQS---FTGGSEISIMCSAT-GYPKPKIVWTMNEMFIMGSH---RYRMTS----EGTLFIKNAVP-------KDAGTYACLASNAAGT-DKQTSTLRYIEAPKLVVEQSELLVALGDTTV-MECKTSGIPPPQVKW--FKGDLELRPSTFLSIDPLVGLLKIQETQDLDAGDYTCVAINEAGRATGRLTLDVGSPPVFIQEPSDVAVEIGSNVTLPCYVQGYPEPK-IKWRRLDNMPVFSRPFSVSFISQLRTGALFISNLWASDKGTYICEAEN----QFGKIQ---SQTTVTVTGLVAP----LIGISPSMASVIEGQPLTLPCTL---LAGNPIPERRWMKNSAMLVQNPYITVRSDGSLHIERVRLQDGGKYTCVASNVAGT--NNKTTSVAVHVLPSI--QH-GQQILSTIEGVP--VTLPCRASGIPKPSITWSKKGELISTSSAKFSAGADGS----------------LYV------VSPGSEESGEYICTATNAAGYAKRKVQLTVYVRPRVFGDQRGLSQDKPVEISVLAGEEAILPCEAKSLPPPIITWAK-DSQLISPFSP----------------RHTFLPS---GSMKITETRVSDSGMYLCVATNIAG 1157 HSP 8 Score: 77.7962 bits (190), Expect = 1.194e-13 Identity = 145/669 (21.67%), Postives = 246/669 (36.77%), Query Frame = 3 Query: 390 NSGYYVCRVTLLTTSEHIISLAVVTVKTPPKSISFHFNKSINVFQEQEFIAIQCSVSGGIPPPKISMYIVKDNAIKR---LKIISSNFPNSTIAEVSAISLWRPHYLENRGFVMCTAINDAGVLTKNTSLLNIKYKPKIKPFVPNTVNAMINQTIDLSCEVYANPAATIQWV--------IMQGLQIIDSSKF--IAKIRPDMDGPLICEAKNYLGSTKETVQLNVLRDPLIHIDSNYR---VPKNSNYSINCRVTSNPPPEFIKWYKLSN--MTDSSAVLISDDAKLNFILIDRSSTGMYACVTQNIQISTTGKRKPANSEKTMFLTVTYKPKEPQILGNK-IISIMKGEKFIIKCSTDRKSPGEPFPTLKWIDVETK--------DIVSDMETFQVINSESRHNGKYKCLAENEIGKSFSRETALVTVNEAPSIITQHKNRKVFLSYSDLPQSISFTCEFRGQPLYEARWRYGNEKIPPSSQDFKIEDHRNISNE---RISQIFTKLTIDLYSRTFSQQTSLRSSPNGRYNCEADNRHGIASLDYFLXXXXXXXXXXNIRHRKIAASLNQNVVMIRCQAESISTMHIKWYKTNEHIVLPFQSKKYSIFEAEVTKYEPERDLFTPGLKVNELTIKDLENDDFSNYSCVASNDQGIKKVNFEVVFKSQP 2306 + G Y+C T + I V V P ++ S + + + C VSG PPP I M++ I KI+ N IA+ + + G C A N AG K + + P IK + + + L C P +I W+ L+I S + IAK + G C A N G + QL+V P + R V N+ + C+ T P P I WYK S+ +SA + L S G+Y CV N A + + + + P P I G+ ++ ++ ++C ++ G P P+L W+ + I+S + +++ G+Y C+A N G+ R+ L V P+I+ + +N V + Q++ C+ ++ +PP + + ++D R + IS+ + L I+ ++ GRY CEA N G +Y + + PP I + ++ A + N++ + C++ I + W K +VL + + I L I E D Y+CVASN G+ K + + +P Sbjct: 1705 DRGQYICVATSVAGEREIKYEVDVLV---PPAVEGGEETSYFIVLANNLLELDCQVSGS-PPPTI-MWLKGGQLIDERDGFKILL-NGRKLVIAQAQ---------VSDTGLYQCVATNIAGDHRKEFEV-TVHVPPTIKSSDLPEKTVVRYKPVTLQCIANGIPNPSITWLKDDQPVNTAHGNLKIQSSGRVLQIAKALLEDAGRYTCVATNAAGEAHQHTQLHVHEPPSLDDAGKMRNETVVVNNPIQLECKATGKPLP-VITWYKDSHPLSGSASAAFLKRGQVLEIGSAQISDAGIYKCVAIN----------SAGATELFYSLQVHVP--PSISGSSSMVEVVVNNLARLEC----EARGIPAPSLTWLKDGSPVSSFSNGIQILSGGRILALTSAQMSDAGRYTCVAVNAAGEK-QRDIDL-RVYAPPNIMGEEQNVSVLIG-----QAVELFCQ--------------SDAVPPPTLMW-LKDGRPLLKRPGLSISENGSVLKIE----------DAQAGDTGRYTCEATNVAGKTEKNYNVNVWVPPSIYGSDELVQLTA-IEGNLITLLCESSGIPPPDLTWKKKGS-LVLADSAGRVHILSGG-----------------RRLQISIAEKADAGLYTCVASNVAGVAKKEYNLQVYIRP 2289 HSP 9 Score: 76.6406 bits (187), Expect = 2.442e-13 Identity = 165/743 (22.21%), Postives = 254/743 (34.19%), Query Frame = 3 Query: 147 FLITPNNATVNSKENLTLECVVDQQNIVYSWEYKPFHIKSNIMSKVLGFCYFEKPCVVPDSESQITISHESRLTIHNISSDNSGYYVCRV-TLLTTSEHIISLAVVTVKTPPKSISFHFNKSINVFQEQEFIAIQCSVSGGIPPPKISMYIVKDNAIKRLKIISSNFPNSTIAEVSAISLWRPHYLENRGFVMCTAINDAGVLTKNTSLLNIKYKPKIKPFVPNTVNAMINQTIDLSCEVYANPAATIQWVIMQGLQIIDSSKFIAK-------IRPDMD--GPLICEAKNYLGSTKETVQLNVLRDPLIHIDS---------NYRVPKNSNYSINCRVTSNPPPEFIKWYK----LSNMTDSSAVLISDDAKLNFILIDRSSTGMYACVTQNIQISTTGKRKPANSEKTMFLTVTYKPKEPQILGNKIISIMKGEKFIIKCSTDRKSPGEPFPTLKWIDV------ETKDIVSDMETFQVINSESRHNGKYKCLAENEIGKSFSRETALVTVNEAPSIITQHKNRKVFLSYSDLPQSISFTCEFRGQPLYEARWRYGNEKIPPSSQDFKIEDHRNISNERISQIFTKLTIDLYSRTFSQQTSLRSSPNGRYNCEADNRHGIASLDYFLXXXXXXXXXXNIRHRKIAASLNQNVVMIRCQAESISTMHIKWYKTNEHIVLPFQSKKYSIFEAEVTKYEPERDLFTPGLKVNELTIKDLENDDFSNYSCVASNDQGIKKVNFEV 2288 F+ P++ V N+TL C Y Y IK + + F P S S I+ L I N+ + + G Y+C + ++ V + P IS I E + + + C++ G P P+ +K ++ N P T+ ++ + R L++ G C A N AG K TS+ + P I+ ++ + + L C P +I W L S+KF A + P + G IC A N G K VQL V P + D V + C S PPP I W K +S + L S K+ + S +GMY CV NI N +++ L+V PK GN+ I + G++ I C+ G P P + W + S T + + G Y C A N G + T + V E PS+ Q I F C +G P +W + ++ I + + L I S+ NG Y C A N G Y L + P + + H + L + + C+ E + I WYK + I + S + ++ K LF + +D YSC A N G + +F V Sbjct: 795 FIQEPSDVAVEIGSNVTLPC--------YVQGYPEPKIKWRRLDNMPVFSR-------PFSVSFISQLRTGALFISNLWASDKGTYICEAENQFGKIQSQTTVTVTGLVAPLIGISPSMASVI----EGQPLTLPCTLLAGNPIPE-------RRWMKNSAMLVQN-PYITVRSDGSLHIERVR-LQDGGKYTCVASNVAGTNNKTTSVA-VHVLPSIQ-HGQQILSTIEGVPVTLPCRASGIPKPSITWSKKGELISTSSAKFSAGADGSLYVVSPGSEESGEYICTATNAAGYAKRKVQLTVYVRPRVFGDQRGLSQDKPVEISVLAGEEAILPCEAKSLPPP-IITWAKDSQLISPFSPRHTFLPSGSMKITETRV--SDSGMYLCVATNIA---------GNVTQSVKLSVHVPPKIQH--GNRHIKVQVGQRVDILCNAH----GSPPPVITWFKSGRPFLDGAQHPGSPDGTLSIEQAVISDAGVYTCAATNIAGSDEAEVT--LHVQEPPSVEDLQPPFNTPFQERLANQRIEFPCPAKGTPKPTIKWLHNGREVTGQEPGVSILEDGAL-----------LVI----------ASVTPHNNGEYICVAVNEAGTTERKYNL-KVHVPPVIRDKEHVTNVSVLTSQLASLYCEVEGTPSPVITWYK--DDIQVTESSTVQIVNNGKILK------LF------------KVSAEDAGRYSCKAINIAGTSQKDFSV 1445 HSP 10 Score: 75.485 bits (184), Expect = 5.254e-13 Identity = 184/829 (22.20%), Postives = 302/829 (36.43%), Query Frame = 3 Query: 21 GTLSTDNETYNLLSNR*-----NMEYFKTFILITLFGNLMD---RSYTLNFLITPNNATVNSK---ENLTLECVVDQQNIVYSWEYKPFHIKSNIMSKVLGFCYFEKPCVVPDSESQITISHESR-LTIHNISSDNSGYYVCRVTLLTTSEHIISLAVVTVKTP-------------PKSISFHFNKSINVFQEQEFIAIQCSVSGGIPPPKISMYIVKDNAIKRLKIISSNFPNSTIAEVSAISLWRPHYLENRGFVMCTAINDAGVLTKNTSLLNIKYKPKIKPF--VPNTVNA---------MINQTIDLSCEVYANPAATIQW-------------VIMQGLQIIDSSKFIAKIRPDMDGPLICEAKNYLGSTKETVQLNVLRDPLIHIDSNYRVPK------NSNYSINCRVTSNPPPEFIKWYKLSN--MTDSSAVLISDDAKLNFILIDRSSTGMYACVTQNIQISTTGKRKPANSEKTMFLTVTYKPKEPQILG--NKIISIMKGEKFIIKCSTDRKSPGEPFPTLKWIDVETKD-------IVSDMETFQVINSESRHNGKYKCLAENEIGKSFSRETALVTVNEAPSIITQHKNRKVFLSYSDLPQSISFTCEFRGQPLYEARWRYGNEKIPPSSQDFKIEDHRNISNERISQIFTKLTIDLYSRTFSQQTSLRSSPNGRYNCEADNRHGIASLDYFLXXXXXXXXXXNIRHRKIAASLNQNVVMIRCQAESISTMHIKWYKTNEHIVLPFQSKKYSIFEAEVTKYEP-ERDLFTPGLKVNELTIKDLENDDFSNYSCVASNDQGIKKVNFEVVFKSQP 2306 G L ++E ++++S N + T L N+ +S+ LN ++P A V+S E++ + + ++ Y P I +F+ + +S I I R L I N DN+G Y C V E I V P PK + N S+ + E E AI P S+ KD + LK + + TIA + + + G C A N AG + + NI+ P + + N ++ +IN + L CE A P T+ W +I+ G +++ I + + + G C A N G ++VL P+I +N +P+ N + + C + NP P W K + D SD L + + TG Y CV +N A S K F + P P ++G ++ +S++ + C G P P L W+ E V T Q+I ++ G Y C+A N+ G+S ++ +TV+ PSI H ++ + + S+S CE P W N ++ P S + +I + R +++ S G+Y C A N G ++ L + PP I+ ++ N V + C A I I W K ++ I +P E + + G K L I + + NY+CVASN +G + NF + + P Sbjct: 2516 GQLLQEDEAHHMMSGGRFLQITNAQVSHTGRYTCLASNIAGDKSKSFRLNVFVSPTIAGVDSDGSPEDVIVILNSPTSLVCEAYSYPPATIT-----------WFKDGTPL-ESNRNIRILPGGRTLQILNAQEDNAGRYSC-VATNEAGEKIKHYEVKVYIPPIIKKGDLLGPGLSPKEVKIRVNSSLTL--ECEAYAI----------PSASLRWYKDG--QPLK----SDDHVTIAASGHTLQIKEAQISDTGRYTCVASNLAGEDELDFDV-NIQVPPSFQKLWEIGNMLDTGRSGEAKDVIINNPLSLHCETNAAPPPTLTWYKDGRPLTSSDRVLILPGGRVLQ----IPRAKVEDAGRYTCVAVNEAGEDSLRYDVHVLLPPVIK-GANSDLPEEVTVLVNKSTQMECSSSGNPAPRNY-WQKDGQILLEDEHHKFQSDGRSLQILNAQITDTGRYVCVAENT----------AGSAKKYFNLNVHVP--PSVIGPNHEHLSVVVNHFISLNCEVS----GFPPPDLSWLKNEEPIKPNTNVLTVPGGRTLQIIRAKISDGGDYTCIAINQAGES--KKKVSLTVHVPPSI-KDHGSQSLSIVNVREGTSVSLECESNAVPPPVITWSK-NGRMIPDSTNVEILTGGQTLHIRRAEV---------------------SDTGQYVCRAINVAGRDDKNFHLNVYVPPTIEGP--ETEVIVETISNPVTLTCDATGIPPPTITWLKNHKPI----------------ENSDPLEVHILSGGSK---LQIARPQRSNSGNYTCVASNMEGKAQKNFILFIQVPP 3244 HSP 11 Score: 71.633 bits (174), Expect = 8.170e-12 Identity = 100/441 (22.68%), Postives = 173/441 (39.23%), Query Frame = 3 Query: 345 ISHESRLTIHNISSDNSGYYVCRVTLLTTSEHIISLAVVTVKTPPKSISFHFNKSINVFQEQEFIAIQCSVSGGIPPPKISMYIVKDNAIKRLKIISSNFPNSTIAEVSAISLWRPHYLENRGFVMCTAINDAGVLTKNTSLLNIKYKPKIKPFVPNTVNAMINQTIDLSCEVYANPAATIQW-----VIMQGLQIID--SSKFIAKIRPDMDGPLICEAKNYLGSTKETVQLNVLRDPLIHID--SNYRVPKNSNYSINCRVTSNPPPEFIKW-YKLSNMTDSSAVLISDDAKLNFILIDRSSTGMYACVTQNIQISTTGKRKPANSEKTMFLTVTYKPKEPQILGNKIISIM-KGEKFIIKCSTDRKSPGEPFPTLKW------IDVETKDIVSDMETFQVINSESRHNGKYKCLAENEIGKSFSRETALVTVNEAPSI 1616 I + L I D++G Y C + + + +TV PP+ S + ++N E + C V+ GIP P I + KD ++ +N A+ + LE+ G C A N AG T+ +L + P P ++ + + LSC+ P + W +I I+ S I K+ + G +C A+N +G K + V P+ D SN+ P N +NC V +P P I+W K +++ S + + L G Y CV N + E++M LT+ P I + +++ G + I+ C ++ GEP PT+ W I + + + + + + +Y+C+A N +G R +V V+ S+ Sbjct: 4126 ILNSGALQIAFAQPDDAGQYTCMAANM--AGSSSVSSTLTVHVPPRIQSTEVHFTVN---ENSQAVLPC-VADGIPTPAI--HWEKDG------VLIANLLGKYTAQPYGELILENVVLEDSGTYTCVANNAAGEDTRIVTLA-VHTLPTFTEL-PGDLSLNKGEQLRLSCKAVGIPLPKLTWTFNNNIIPAHFDSINGHSELVIEKVSKEDSGTYVCTAENSVGFVKAIGFVYVKEPPVFKGDYPSNWIEPLGGNAILNCEVKGDPAPT-IQWSRKGADIEISHRIRQLGNGSLAIYGTVNEDAGDYTCVAAN---------EAGMVERSMSLTLQ---SSPIITLEPVETVVDAGGRVILDC----QAAGEPQPTITWSRQGQPISWDNRLSMLPNSSLYIAAARKEDTSEYECVARNLMGSVLVRVPVIVQVHGGFSL 4533 HSP 12 Score: 67.0106 bits (162), Expect = 2.195e-10 Identity = 93/431 (21.58%), Postives = 171/431 (39.68%), Query Frame = 3 Query: 699 LENRGFVMCTAINDAGVLTKNTSLLNIKYKPKIKPFVPNTVNAMINQTIDLSCEVYANPAATIQWV-IMQGLQIIDSSKF--IAKIRPDMDGPLICEAKNYL-------GSTKETVQLNVLRDPLIHIDSNYRVPKNSNY------SINCRVTSNPPPEFIKWYKLSNMTDSSAVLISDDAKLNFILIDRSSTGMYACVTQNIQISTTGKRKPANSEKTMFLTVTYKPKEPQILGNKIISIMKGEKFIIKCSTDRKSPGEPFPTLKWI--DVETK-----DIVSDMETFQVINSESRHNGKYKCLAENEIGKSFSRETALVTVNEAPSIITQHKNRKVFLSYSDLPQSISFTCEFRGQPLYEARWRYGNEKIPPSSQDFKIEDHRNISNERISQIFTKLTIDLYSRTFSQQTSLRSSPNGRYNCEADNRHG 1922 L + GF C A++ AG + + ++ P I PN V + L+C V + + W + +++ DS++ +A + ++ I +A Y GS +V L V P + + +PKN ++ SI C T P P+ + + S ++ + L G YAC+ N ++T L PK ++ + + G+ +++C K+ G P P +KW D+E + I + ++ ++ G Y C+A NE G++ R T + V P I + + V ++ +++ C +G P + +WR + +P S+ F + IS R +F ++L +S G Y CEA+N+ G Sbjct: 491 LSDEGFYDCIAVSSAGT-GRAQTFFDVSEPPPIIQL-PNNVTVTPGERAVLACLVISAVDYNLTWQRSGRDIRLADSARIRTLANLSLELRSVKIGDAGEYRCVVSSEGGSAAASVFLTVQEKPKVTV-----MPKNQSFTGGSEISIMCSATGYPKPKIVWTMNEMFIMGSHRYRMTSEGTLFIKNAVPKDAGTYACLASNAA---------GTDKQTSTLRYIEAPK--LVVEQSELLVALGDTTVMEC----KTSGIPPPQVKWFKGDLELRPSTFLSIDPLVGLLKIQETQDLDAGDYTCVAINEAGRATGRLT--LDVGSPPVFIQEPSDVAV-----EIGSNVTLPCYVQGYPEPKIKWRR-LDNMPVFSRPFSVS---FISQLRTGALFI--------------SNLWASDKGTYICEAENQFG 874 HSP 13 Score: 55.8398 bits (133), Expect = 5.491e-7 Identity = 84/365 (23.01%), Postives = 143/365 (39.18%), Query Frame = 3 Query: 702 ENRGFVMCTAINDAGVLTKNTSLLNIKYKPKIKPF-VPNTVNAMINQTIDLSCEVYANPAATIQW-------VIMQGLQIIDSSKF--IAKIRPDMDGPLICEAKNYLGSTKETVQLNVLRDP-LIHID--SNYRVPKNSNYSINCRVTSNPPPEFIKWYKLSNMTDSS--AVLISDDAKLNFILIDRSSTGMYACVTQNIQISTTGKRKPANSEKTMFLTVTYKPKEPQILGNKIISIMKGEKFIIKCSTDRKSPGEPFPTLKW-----IDVETKDIVSDMETFQVINSESRH---NGKYKCLAENEIGKSFSRETALVTVNEAPSIITQHKNRKVFLSYSDLPQSISFTCEFRGQPLYEARWR 1727 E+ G C A N+AG ++K+ +L + P I P V+ ++N ++LSC PA I W + + +Q ++ ++ + + G C A + G + + V P + +D ++ V +N ++ C+ + PPP I W K ++ ++S L D T Y CV NI TT + LTV P G + + + + ++C ++ G P P + W + E+ S +E ++ ES H G+Y C+A N G R + V+ PSI N V ++ + CE G P WR Sbjct: 3498 EDTGKYTCVATNEAGEVSKHF-VLKVLEPPHINGSEGPGEVSVIVNNPLELSCIASGIPAPKISWMKDGRPFLQTEQVQTLEGGAILRVSSAQVEDTGRYTCLASSPAGDDDKEYLVRVHVPPNIAGMDEAQDFTVLRNRQVTLECKSDAVPPP-VIMWLKNREQLQATPRVRILSGGRYLQINNADLGDTANYTCVASNIAGKTT---------REFNLTVNVPPSIGG--GPQSLVTLLNKSIALEC----RAEGVPAPRITWRKDGVVLAESHARYSILEN-GFLHIESAHVTDTGRYLCMATNVAGT--DRRRIDLQVHVPPSIAMGPTNVTVTVN-----VQTTLACEATGIPKPSVTWR 3837
BLAST of hemicentin-1 isoform X2 vs. Ensembl Mouse
Match: Hmcn1 (hemicentin 1 [Source:MGI Symbol;Acc:MGI:2685047]) HSP 1 Score: 102.834 bits (255), Expect = 2.293e-21 Identity = 168/689 (24.38%), Postives = 265/689 (38.46%), Query Frame = 3 Query: 363 LTIHNISSDNSGYYVCRVTLLTTSEHIISLAVVTVKTPPKSIS-FHFNKSINVFQEQEFIAIQCSVSGGIPPPKISMYIVKDNAIKRLKIISSNFPNSTIAEVSA---ISLWRPHYLENRGFVMCTAINDAGVLTKNTSLLNIKYKPKIKPFVPNT---VNAMINQTIDLSCEVYANPAATIQWVIMQGLQIIDSSKF----------IAKIRPDMDGPLICEAKNYLGSTKETVQLNVLRDPLIHI-DSNYRVPKNSN-YSINCRVTSNPPPEFIKWYK----LSNMTDSSAVLISDDAKLNFILIDRSSTGMYACVTQNIQISTTGKRKPANSEKTMFLTVTYKPKEPQILGNKI---ISIMKGEKFIIKCSTDRKSPGEPFPTLKWI---------DVETKDIVSDMETFQVINSESRHNGKYKCLAENEIGKSFSRETALVTVN--EAPSIITQHKNRKVFLSYSDLPQSISFTCEFRGQPLYEARWRYGNEKIPPSSQDFKIEDHRNISNERISQIFTKLTIDLYSRTFSQQTSLRSSPNGRYNCEADNRHGIASLDYFLXXXXXXXXXXNIRHRKIAASLNQNVVMIRCQAESISTMHIKWYKTNEHIVLPFQSKKYSIFEAEVTKYEPERDLFTPGLKVNELTIKDLENDDFSNYSCVASNDQGIKKVNFEVVFKSQPDPPY 2318 L I N ++G YVC T+ + V PP I H + S+ V FI++ C VS G PPP +S ++ + IK PN+ + V + + R + + G C AIN AG K S L + P IK + VN ++ L CE A P I W G I DS+ I + G +C A N G + LNV P I ++ V SN ++ C T PPP I W K + N ++S +KL RS++G Y CV N++ GK A +F+ V P + G ++ +S++ GE + C+ D G P P L+W+ + E + +D T + + + GKY C+A N G+ E + +N P I + + ++ D SI+ C+ G P + W +P SS R +S ++ +I D+ Y C A NR G+ S Y L + PP + + +I + M C + + W + + + +A +T + T G+ L + E +D Y+CVA+N+ G +V+ V K +PP+ Sbjct: 2927 LQILNAQITDTGRYVCVAE--NTAGSAKKYFNLNVHVPPSVIGPNHEHLSVVV---NHFISLNCEVS-GFPPPDLS-WLKNEEPIK---------PNTNVLTVPGGRTLQIIRAK-ISDGGDYTCIAINQAGESKKKVS-LTVHVPPSIKDHGSQSLSIVNVREGTSVSLECESNAVPPPVITWS-KNGRMIPDSTNVEILTGGQTLHIRRAEVSDTGQYVCRAINVAGRDDKNFHLNVYVPPTIEGPETEVIVETISNPVTLTCDATGIPPPT-ITWLKNHKPIENSDPLEVHILSGGSKLQIARPQRSNSGNYTCVASNME----GK---AQKNFILFIQV-----PPSVAGAEVPSEVSVLLGENVELVCNAD----GIPTPHLQWLRDGKPIVNGETERVRVTTDGSTLNIYRALTSDMGKYTCVATNPAGE----EDRIFNLNVYVPPKIRGNKEEAEKLMALVD--TSINIECKATGTPPPQINWLKNGLPLPISSH------IRLLSAGQVVRIVRAQVSDI----------------AVYTCVASNRAGVDSKHYSLQVFVPPNMDNAMGTEEITIVKGSSTSMT-CFTDGTPAPSMSWLRDGQPLAP----------DAHLT-------VSTQGMV---LQLIKAETEDTGKYTCVATNEAG--EVSKHFVLKVL-EPPH 3527 HSP 2 Score: 102.834 bits (255), Expect = 2.669e-21 Identity = 154/697 (22.09%), Postives = 258/697 (37.02%), Query Frame = 3 Query: 315 VVPDSESQITISHESRLTIHNISSDNSGYYVCRVTLLTTSE----HIISLAVVTVKTPPKSISFHFNKSINVFQEQEFIAIQCSVSGGIPPPKISMYIVKDNAIKRLKIISSNFPNST--IAEVSAISLWRPHYLENRGFVMCTAINDAGVLTKNTSLLNIKYKPKIKPF-VPNTVNAMINQTIDLSCEVYANPAATIQWVIMQGLQIIDSSKFIAKIRPDMD------------GPLICEAKNYLGSTKETVQLNVLRDPLIHID----SNYRVPKNSNYSINCRVTSNPPPEFIKWYK--LSNMTDSSAVLISDDAKLNFILIDRSSTGMYACVTQNIQISTTGKRKPANSEKTMFLTVTYKPKEPQILGNKIISIMKGEKFIIKCSTDRKSPGEPFPTLKWIDVETKDIVSDME--------TFQVINSESRHNGKYKCLAENEIGKSFSRETALVTVNEAPSIITQHKNRKVFLSYSDLPQSISFTCEFRGQPLYEARWRYGNEKIPPSSQDFKIEDHRNISNERISQIFTKLTIDLYSRTFSQQTSLRSSPNGRYNCEADNRHGIASLDYFLXXXXXXXXXXNIRHRKIAASLNQNVVMIRCQAESISTMHIKWYKTNEHIVLPFQSKKYSIFEAEVTKYEPERDLFTPGLKVNELTIKDLENDDFSNYSCVASNDQGIKKVNFEVVFKSQP 2306 ++PDS + ++ L I ++G YVCR + + H+ T++ P + V + + C +G IPPP I+ +K K I ++ P ++ S + + RP N G C A N G KN +L I+ P + VP+ V+ ++ + ++L C P +QW + G I++ ++ D G C A N G LNV P I + +++ +I C+ T PPP+ I W K L S L+S + + S +Y CV N + K L V P +G + I+I+KG + C TD G P P++ W+ + + + D Q+I +E+ GKY C+A NE G+ S+ L V E P I +V + ++ + +C G P + W ++D R + T+ L + +S + GRY C A + G +Y + + PP I + N+ V + C+++++ I W K E + + P + + G L I + + D +NY+CVASN G F + P Sbjct: 3098 MIPDSTNVEILTGGQTLHIRRAEVSDTGQYVCRAINVAGRDDKNFHLNVYVPPTIEGP--------ETEVIVETISNPVTLTCDATG-IPPPTITW-------LKNHKPIENSDPLEVHILSGGSKLQIARPQR-SNSGNYTCVASNMEGKAQKNF-ILFIQVPPSVAGAEVPSEVSVLLGENVELVCNADGIPTPHLQW-LRDGKPIVNGETERVRVTTDGSTLNIYRALTSDMGKYTCVATNPAGEEDRIFNLNVYVPPKIRGNKEEAEKLMALVDTSINIECKATGTPPPQ-INWLKNGLPLPISSHIRLLSAGQVVRIVRAQVSDIAVYTCVASN---------RAGVDSKHYSLQVFVPPNMDNAMGTEEITIVKGSSTSMTCFTD----GTPAPSMSWLR-DGQPLAPDAHLTVSTQGMVLQLIKAETEDTGKYTCVATNEAGE-VSKHFVL-KVLEPPHINGSEGPGEVSVIVNN---PLELSCIASGIPAPKISW---------------MKDGRPF-------LQTEQVQTLEGGAILRVSSAQVEDTGRYTCLASSPAGDDDKEYLVRVHVPPNIAGMDEAQDFTVLRNRQVTL-ECKSDAVPPPVIMWLKNREQL-----------------QATPRVRILSGG---RYLQINNADLGDTANYTCVASNIAGKTTREFNLTVNVPP 3712 HSP 3 Score: 98.9821 bits (245), Expect = 3.460e-20 Identity = 151/698 (21.63%), Postives = 266/698 (38.11%), Query Frame = 3 Query: 315 VVPDSESQITI-SHESRLTIHNISSDNSGYYVC---RVTLLTTSEHIISLAVVTVKTPPKSISFHFNKSINVFQEQEFIAIQCSVSGGIPPPKISMYIVKDNAIKRLKIISSNFPNSTIAEVSAISLWRPHYLENRGFVMCTAINDAGVLTKNTSLLNIKYKPKI--KPFVPNTVNAMINQTIDLSCEVYANPAATIQWV-------IMQGLQIIDSSKFI--AKIRPDMDGPLICEAKNYLGSTKETVQLNVLRDPLIHIDS---NYRVPKNSNYSINCRVTSNPPPEFIKWYKLSNM--TDSSAVLISDDAKLNFILIDRSSTGMYACVTQNIQISTTGKRKPANSEKTMFLTVTYKPKEPQILGNKIISIMKGEKFIIKCSTDRKSPGEPFPTLKWIDVETK-------DIVSDMETFQVINSESRHNGKYKCLAENEIGKSFSRETALVTVNEAPSIITQHKNRKVFLSYSDLP----QSISFTCEFRGQPLYEARWRYGNEKIPPSSQDFKIEDHRNISNERISQIFTKLTIDLYSRTFSQQTSLRSSPNGRYNCEADNRHGIASLDY---------FLXXXXXXXXXXNIRHRKIAASLNQNVVMIRCQAESISTMHIKWYKTNEHIVLPFQSKKYSIFEAEVTKYEPERDLFTPGLKVNELTIKDLENDDFSNYSCVASNDQGIKKVNFEV 2288 V+ DS ++ I S RL I ++G Y C V + E+ + + + P + S I V + + I+++C V G IP P ++ ++ + + K + I + I + ++ + G +C A+N AG+ K L ++ P I VP V+ + ++ L+CE P +I W+ + ++I+ + + + RP+ G C +N G ++ L+VL P I ++ + ++ + + ++ C V NP P+ I W+K + D + ++S L S TG Y C+ NI K + +F++ T + +I I+ ++ C P T+ W T I+ T Q++N++ + G+Y C+A NE G+ V + P II + LS ++ S++ CE P RW Q K +DH +TI T Q + S GRY C A N G LD+ F + + R + + N + + C+ + + WYK P S +R L PG +V L I + +D Y+CVA N+ G + ++V Sbjct: 2236 VLADSAGRVHILSGGRRLQISIAEKADAGLYTCVASNVAGVAKKEYNLQVYI----RPSITNSGGHRPEITVIRGKS-ISLECEVQG-IPQPTVT-WMKDGRPLTKGKGVE-------ILDEGRILQLKNVHVSDTGRYVCVAVNVAGMTDKRYDL-SVHAPPSIIGNHGVPENVSVVEKSSVSLTCEASGIPLPSITWLKDGWPVNLGSSVKILSGGRMLRLMQTRPEDAGQYTCIVRNAAGEDRKMFGLSVLVPPHIVGENTLEDVKIKEKQSVTLTCEVRGNPVPQ-ITWHKDGQLLQEDEAHHMMSGGRFLQITNAQVSHTGRYTCLASNI-----AGDKSKSFRLNVFVSPTIAGVDSDGSPEDVIVILNSPTSLV-CEAYSYPPA----TITWFKDGTPLESNRNIRILPGGRTLQILNAQEDNAGRYSCVATNEAGEKIKHYEVKVYI---PPIIKKGDLLGPGLSPKEVKIRVNSSLTLECEAYAIPSASLRWYK-------DGQPLKSDDH--------------VTIAASGHTL-QIKEAQISDTGRYTCVASNLAGEDELDFDVNIQVPPSFQKLWEIGNMLDTGRSGEAKDVIINNPLSLHCETNAAPPPTLTWYKDGR----PLTSS--------------DRVLILPGGRV--LQIPRAKVEDAGRYTCVAVNEAGEDSLRYDV 2862 HSP 4 Score: 93.2041 bits (230), Expect = 2.186e-18 Identity = 152/679 (22.39%), Postives = 265/679 (39.03%), Query Frame = 3 Query: 363 LTIHNISSDNSGYYVCRVTLLTTSEHIISLAVVTVKTPPKSISFHFNKSINVFQEQEFIAIQCSVSGGIPPPKISMYIVKDNAIKRL------KIISSNFPNSTIAEVSAISLWRPHYLENRGFVMCTAINDAGVLTKNTSLLNIKYKPKIKPFVPNTVNAMINQTIDLSCEVYANPAATIQWVIMQGLQIIDSSKFIA-----------KIRPDMDGPLICEAKNYLGSTKETVQLNVLRDPLIHI-DSNYRVPKNSNYSINCRVTSNPPPEFIKWYKLSN-MTDSSAVLISDDAKLNFILIDRSSTGMYACVTQNIQISTTGKRKPANSEKTMFLTVTYKPKEPQILGNKI-ISIMKGEKFIIKCSTDRKSPGEPFPTLKW-------IDVETKDIVSDMETFQVINSESRHNGKYKCLAENEIGKSFSRET----ALVTVNEAPSIITQHKNRKVFLSYSDLPQSISFTCEFRGQPLYEARWRYGNEKIPPSSQDFKIEDHRNISNERISQIFTKLTIDLYSRTFSQQTSLRSSPNGRYNCEADNRHGIASLDYFLXXXXXXXXXXNIRHRKIAASLNQNVVMIRCQAESISTMHIKWYKTNEHIVLPFQSKKYSIFEAEVTKYEPERDLFTPGLKVNELTIKDLENDDFSNYSCVASNDQGIKKVNFEVVFKSQP 2306 L I + S D++ Y C VT + + +TV+ PP +I+ ++ ++ ++ A+ + G+P P I N ++ L +I+SS AI + L + G C A N AG ++ +L ++ P I+P P+ ++ ++N I L CE P I W +G+ +I S K +A +R D G +C A+N G+ V+LNV P+I Y V + S+ C +PPP+ I W+K + +T+S I + L G Y C+ N+ +S + LTV P+ I ++ ++ + + ++ C D G P P + W ++ K + N +G Y C+A N G+ T L T E P ++ +K ++ LS C+ G PL + W + N IP + I H + E++S+ +G Y C A+N G F+ +K PP+ K + I L N ++ C+ + I+W + I + + ++ L L I N+D +Y+CVA+N+ G+ + + + +S P Sbjct: 3860 LVIISPSVDDTASYECTVT--SDAGEDKRAVDLTVQVPP-TIA---DEPMDFLVTRQAPAVMTCSASGVPVPSIHW---TKNGLRLLPRGDGYRILSSG----------AIEIPTTQ-LNHAGRYTCVARNAAGSAHRHVTL-RVQEPPVIQP-QPSELDVILNNPILLPCEATGIPTPFITWQ-KEGINVITSGKSLAILPSGSLQISRAVRGDA-GTYMCVAQNPAGTALGKVKLNVQVPPVISSHQKEYVVTMDKPVSLLCETEGSPPPD-ITWHKDGHALTESIRQRILNSGALQIAFAQPDDAGQYTCMAANMA---------GSSSVSSTLTVHVPPR---IQSTEVHFTVNENSQAVLPCVAD----GIPTPAIHWEKDGVLIANLLGKYTAQPYGELILENVVLEDSGTYTCVANNAAGEDTRIVTLAVHTLPTFTELPGDLSLNKGEQLRLS-----------CKAVGIPLPKLTWTFNNNIIP--AHFDSINGHSELVIEKVSK----------------------EDSGTYVCTAENSVGFVKAIGFVYVKEPPVFKGDYPSNWIEP-LGGNAIL-NCEVKGDPAPTIQWSRKGADIEISHRIRQ---------------------LGNGSLAIYGTVNEDAGDYTCVAANEAGMVERSMSLTLQSSP 4439 HSP 5 Score: 90.5077 bits (223), Expect = 1.665e-17 Identity = 130/553 (23.51%), Postives = 217/553 (39.24%), Query Frame = 3 Query: 699 LENRGFVMCTAINDAGVLTKNTSL---LNIKYKPKIKPF---VPNTVNAMINQTIDLSCEVYANPAATIQWVIMQGLQII---DSSKFIAKIRPDM--------DGPLICEAKNYLGSTKETVQLNVLRDPLIHIDSNYR---VPKNSNYSINCRVTSNPPPEFIKWYKLSN--MTDSSAVLISDDAKLNFILIDRSSTGMYACVTQNIQISTTGKRKPANSEKTMFLTVTYKP--KEPQILGNKIISIMKGEKFIIKCSTDRKSPGEPFPTLKWI-------DVETKDIVSDMETFQVINSESRHNGKYKCLAENEIGKSFSRETALVTVNEAPSIITQHKNRKVFLSYSDLPQSISFTCEFRGQPLYEARWRYGNEKIPPSSQDFKIEDHRNISNERISQIFTKLTIDLYSRTFSQQTSLRSSPNGRYNCEADNRHGIASLDYFLXXXXXXXXXXNIRHRKIAASLNQNVVMIRCQAESISTMHIKWYKTNEHIVLPFQSKKYSIFEAEVTKYEPERDLFTPGLKVNELTIKDLENDDFSNYSCVASNDQG 2264 +E+ G C A+N+AG SL +++ P IK +P V ++N++ + C NPA W + QI+ + KF + R G +C A+N GS K+ LNV P + I N+ V N S+NC V+ PPP+ + W K +++ + + L I S G Y C+ N + S+K + LTV P K+ I+++ +G ++C ++ P P + W D +I++ +T + +E G+Y C A N G+ V V P I + + + S+ ++ TC+ G P W +++H+ I N ++ L + Q + S +G Y C A N G A ++ L I+ PP + +++ L +NV ++ C A+ I T H++W + + IV E ER T + L I D Y+CVA+N G Sbjct: 2839 VEDAGRYTCVAVNEAG----EDSLRYDVHVLLPPVIKGANSDLPEEVTVLVNKSTQMECSSSGNPAPRNYW--QKDGQILLEDEHHKFQSDGRSLQILNAQITDTGRYVCVAENTAGSAKKYFNLNVHVPPSV-IGPNHEHLSVVVNHFISLNCEVSGFPPPD-LSWLKNEEPIKPNTNVLTVPGGRTLQIIRAKISDGGDYTCIAIN---------QAGESKKKVSLTVHVPPSIKDHGSQSLSIVNVREGTSVSLECESNAVPP----PVITWSKNGRMIPDSTNVEILTGGQTLHIRRAEVSDTGQYVCRAINVAGRDDKNFHLNVYV---PPTIEGPETEVIVETISN---PVTLTCDATGIPPPTITW---------------LKNHKPIENSDPLEVHI-----LSGGSKLQIARPQRSNSGNYTCVASNMEGKAQKNFILFIQVPPSVAGAEVPSEVSVLLGENVELV-CNADGIPTPHLQWLRDGKPIV----------------NGETERVRVT--TDGSTLNIYRALTSDMGKYTCVATNPAG 3325 HSP 6 Score: 89.7373 bits (221), Expect = 2.293e-17 Identity = 162/689 (23.51%), Postives = 254/689 (36.87%), Query Frame = 3 Query: 348 SHESRLTIHNISSDNSGYYVCRVTLLTTSEHIISLAVVTVKTPP--KSISFHFNKSINVFQEQEFIAIQCSVSGGIPPPKISMYIVKDNAIKRLKIISSNFPNSTIAEVSAISLWRPHYLENRGFVMCTAINDAGVLTKNTSLLNIKYKPKI--KPFVPNTVNAMINQTIDLSCEVYANPAATIQW-------VIMQGLQIIDSSKFIA--KIRPDMDGPLICEAKNYLGSTKETVQLNVLRDPLI---HIDSNYRVPKNSNYSINCRVTSNPPPEFIKWYKLSN---MTDSSAVLISDDAKLNFILIDRSSTGMYACVTQNIQISTTGKRKPANSEKTMFLTVTYKPKEPQILGNKI---ISIMKGEKFIIKCSTDRKSPGEPFPTLKWIDVETKDIVSDMETFQVINSESRH--------NGKYKCLAENEIG---KSFSRETALVTVNEAPSI---ITQHKNRKVFLSYSDLPQSISFTCEFRGQPLYEARWRYGNEKIPPSSQDFKIEDHRNISNERISQIFTKLTIDLYSRTFSQQTSLRSSPNGRYNCEADNRHGIASLDYFLXXXXXXXXXXNIRHRKIAASLNQNVVMIRCQAESISTMHIKWYKTNEHIVLPFQSKKYSIFEAEVTKYEPERDLFTPGLKVNELTIKDLENDDFSNYSCVASNDQGIKKVNFEVVFKSQP 2306 S + L+I ++G Y C T + S+ + + V+ PP + + FN + I C G P P I + + ++ P +I E A+ + N G +C A+N+AG T+ L + P I K V N V+ + +Q L CEV P+ I W +QI+++ K + K+ + G C+A N G++++ +NVL P I S V N N ++ C T P P I W+K + D + L L+ RS G Y C N GK+ K + LTV Y P P I G I IS + ++C T G P P + W + + + S + + + H + Y C A N G KSF V + P+I +T N++V + QS+ C+ G P W + +P + D H +++ +I + L +D G+Y C A + G + Y + + PP ++ L N++ + CQ I W K + I ERD F L +L I + D Y CVA+N G + FEV P Sbjct: 1220 SPDGTLSIEQAVISDAGVYTCAATNIAGSDE--AEVTLHVQEPPSVEDLQPPFNTPFQERLANQRIEFPCPAKG-TPKPTIKW-------LHNGREVTGQEPGVSILEDGALLVIASVTPHNNGEYICVAVNEAGT-TERKYNLKVHVPPVIRDKEHVTN-VSVLTSQLASLYCEVEGTPSPVITWYKDDIQVTESSTVQIVNNGKILKLFKVSAEDAGRYSCKAINIAGTSQKDFSVNVLVPPSILGASSPSEVSVVLNHNVTLQCPGTGVPFPA-IHWFKDGKPLFLGDPNIELSDRGQSLHLRNARRSDKGRYQCTVSN----AAGKQA-----KDIKLTV-YVP--PSIKGGNITTEISALLNSIVKLECETR----GLPVPAITWYK-DGQVVTSSSQALYIDKGQLLHIQRAQVSDSATYTCHAANVAGTAEKSFH-----VDIYVPPTIEGDLTAPSNKQVIIG-----QSLILECKAAGNPPPILTWL--KDGVPVKASD---NIHIEAGGKKL-EILSALEVD----------------RGQYICVATSVAGEREIKYEVDVLVPPAVEGG-EETSYFIVLANNLLELDCQVSGSPPPTIMWLKGGQLI--------------------DERDGFKILLNGRKLVIAQAQVSDTGLYQCVATNIAGDHRKEFEVTVHVPP 1825 HSP 7 Score: 77.411 bits (189), Expect = 1.342e-13 Identity = 171/739 (23.14%), Postives = 277/739 (37.48%), Query Frame = 3 Query: 159 PNNATVNSKENLTLEC-VVDQQNIVYSWEYKPFHIKSNIMSKVLGFCYFEKPCVVPDSESQITISHESRLTIHNISSDNSGYYVCRVTLLTTSEHIISLAVVTVKTPPKSISFHFNKSINVFQEQEFIAIQCSVSGGIPPPKI-----SMYIVKDNAIKRLKIISSNFPNSTIAEVSAISLWRPHYLENRGFVMCTAINDAGVLTKNTSLLNIKYKPKIKPFVPNTVNAMINQTIDLSCEVYANPAATIQWVIMQGLQIIDSSKFIA--------KIRPDMD---GPLICEAKNYLGSTKETVQLNVLRDPL-IHIDSNYRVPKNSNYSINCRVTSNPPPEFIKWYKLSNMTDSS---AVLISDDAKLNFILIDR---SSTGMYACVTQNIQISTTGKRKPANSEKTMFLTVTYKPKEPQILG--NKIISIMKGEKFIIKCSTDRKSPGEPFPTLKWIDVETKDI------VSDMETFQVINSESRHNGKYKCLAENEIGKSFSRETALVTVNEAPSIITQHKNRKVFLSYSDLPQSISFTCEFRGQPLYEARWRYGNEKIPPSSQDFKIEDHRNISNERISQIFTKLTIDLYSRTFSQQTSLRSSPNGRYNCEADNRHGIASLDYFLXXXXXXXXXXNIRH----RKIAAS-LNQNVVMIRCQAESISTMHIKWYKTNEHIVLPFQSKKYSIFEAEVTKYEPERDLFTPGLKVNELTIKDLENDDFSNYSCVASNDQG 2264 PNN TV E L C V+ + +W+ I+ + DS T+++ S L + ++ ++G Y C V+ + + +TV+ PK N+S F I+I CS + G P PKI M+I+ + R ++ S T+ +A+ ++ G C A N AG K TS L PK+ + A+ + T+ + C+ P ++W +G + S F++ KI+ D G C A N G + L+V P+ I S+ V SN ++ C V P P+ IKW +L NM S +V + + I S G Y C +N GK + S+ T+ +T P ++G + S+++G+ + C+ G P P +W+ + V + + + GKY C+A N G + +T V V+ PSI QH +++ + +P ++ C G P W E I SS F + LY S S +G Y C A N G A L + P + + R + + S L ++ C+A+S+ I W K + ++ PF R F P + I + D Y CVA+N G Sbjct: 526 PNNVTVTPGERAVLACLVISAVDYNLTWQRSGRDIR------------------LADSARIRTLANLS-LELRSVKIGDAGEYRCVVS--SEGGSAAASVFLTVQEKPKVTVMPKNQS---FTGGSEISIMCSAT-GYPKPKIVWTMNEMFIMGSH---RYRMTS----EGTLFIKNAVP-------KDAGTYACLASNAAGT-DKQTSTLRYIEAPKLVVEQSELLVALGDTTV-MECKTSGIPPPQVKW--FKGDLELRPSTFLSIDPLVGLLKIQETQDLDAGDYTCVAINEAGRATGRLTLDVGSPPVFIQEPSDVAVEIGSNVTLPCYVQGYPEPK-IKWRRLDNMPVFSRPFSVSFISQLRTGALFISNLWASDKGTYICEAEN----QFGKIQ---SQTTVTVTGLVAP----LIGISPSMASVIEGQPLTLPCTL---LAGNPIPERRWMKNSAMLVQNPYITVRSDGSLHIERVRLQDGGKYTCVASNVAGT--NNKTTSVAVHVLPSI--QH-GQQILSTIEGVP--VTLPCRASGIPKPSITWSKKGELISTSSAKFSAGADGS----------------LYV------VSPGSEESGEYICTATNAAGYAKRKVQLTVYVRPRVFGDQRGLSQDKPVEISVLAGEEAILPCEAKSLPPPIITWAK-DSQLISPFSP----------------RHTFLPS---GSMKITETRVSDSGMYLCVATNIAG 1157 HSP 8 Score: 77.411 bits (189), Expect = 1.522e-13 Identity = 145/669 (21.67%), Postives = 246/669 (36.77%), Query Frame = 3 Query: 390 NSGYYVCRVTLLTTSEHIISLAVVTVKTPPKSISFHFNKSINVFQEQEFIAIQCSVSGGIPPPKISMYIVKDNAIKR---LKIISSNFPNSTIAEVSAISLWRPHYLENRGFVMCTAINDAGVLTKNTSLLNIKYKPKIKPFVPNTVNAMINQTIDLSCEVYANPAATIQWV--------IMQGLQIIDSSKF--IAKIRPDMDGPLICEAKNYLGSTKETVQLNVLRDPLIHIDSNYR---VPKNSNYSINCRVTSNPPPEFIKWYKLSN--MTDSSAVLISDDAKLNFILIDRSSTGMYACVTQNIQISTTGKRKPANSEKTMFLTVTYKPKEPQILGNK-IISIMKGEKFIIKCSTDRKSPGEPFPTLKWIDVETK--------DIVSDMETFQVINSESRHNGKYKCLAENEIGKSFSRETALVTVNEAPSIITQHKNRKVFLSYSDLPQSISFTCEFRGQPLYEARWRYGNEKIPPSSQDFKIEDHRNISNE---RISQIFTKLTIDLYSRTFSQQTSLRSSPNGRYNCEADNRHGIASLDYFLXXXXXXXXXXNIRHRKIAASLNQNVVMIRCQAESISTMHIKWYKTNEHIVLPFQSKKYSIFEAEVTKYEPERDLFTPGLKVNELTIKDLENDDFSNYSCVASNDQGIKKVNFEVVFKSQP 2306 + G Y+C T + I V V P ++ S + + + C VSG PPP I M++ I KI+ N IA+ + + G C A N AG K + + P IK + + + L C P +I W+ L+I S + IAK + G C A N G + QL+V P + R V N+ + C+ T P P I WYK S+ +SA + L S G+Y CV N A + + + + P P I G+ ++ ++ ++C ++ G P P+L W+ + I+S + +++ G+Y C+A N G+ R+ L V P+I+ + +N V + Q++ C+ ++ +PP + + ++D R + IS+ + L I+ ++ GRY CEA N G +Y + + PP I + ++ A + N++ + C++ I + W K +VL + + I L I E D Y+CVASN G+ K + + +P Sbjct: 1705 DRGQYICVATSVAGEREIKYEVDVLV---PPAVEGGEETSYFIVLANNLLELDCQVSGS-PPPTI-MWLKGGQLIDERDGFKILL-NGRKLVIAQAQ---------VSDTGLYQCVATNIAGDHRKEFEV-TVHVPPTIKSSDLPEKTVVRYKPVTLQCIANGIPNPSITWLKDDQPVNTAHGNLKIQSSGRVLQIAKALLEDAGRYTCVATNAAGEAHQHTQLHVHEPPSLDDAGKMRNETVVVNNPIQLECKATGKPLP-VITWYKDSHPLSGSASAAFLKRGQVLEIGSAQISDAGIYKCVAIN----------SAGATELFYSLQVHVP--PSISGSSSMVEVVVNNLARLEC----EARGIPAPSLTWLKDGSPVSSFSNGIQILSGGRILALTSAQMSDAGRYTCVAVNAAGEK-QRDIDL-RVYAPPNIMGEEQNVSVLIG-----QAVELFCQ--------------SDAVPPPTLMW-LKDGRPLLKRPGLSISENGSVLKIE----------DAQAGDTGRYTCEATNVAGKTEKNYNVNVWVPPSIYGSDELVQLTA-IEGNLITLLCESSGIPPPDLTWKKKGS-LVLADSAGRVHILSGG-----------------RRLQISIAEKADAGLYTCVASNVAGVAKKEYNLQVYIRP 2289 HSP 9 Score: 76.2554 bits (186), Expect = 2.886e-13 Identity = 165/743 (22.21%), Postives = 254/743 (34.19%), Query Frame = 3 Query: 147 FLITPNNATVNSKENLTLECVVDQQNIVYSWEYKPFHIKSNIMSKVLGFCYFEKPCVVPDSESQITISHESRLTIHNISSDNSGYYVCRV-TLLTTSEHIISLAVVTVKTPPKSISFHFNKSINVFQEQEFIAIQCSVSGGIPPPKISMYIVKDNAIKRLKIISSNFPNSTIAEVSAISLWRPHYLENRGFVMCTAINDAGVLTKNTSLLNIKYKPKIKPFVPNTVNAMINQTIDLSCEVYANPAATIQWVIMQGLQIIDSSKFIAK-------IRPDMD--GPLICEAKNYLGSTKETVQLNVLRDPLIHIDS---------NYRVPKNSNYSINCRVTSNPPPEFIKWYK----LSNMTDSSAVLISDDAKLNFILIDRSSTGMYACVTQNIQISTTGKRKPANSEKTMFLTVTYKPKEPQILGNKIISIMKGEKFIIKCSTDRKSPGEPFPTLKWIDV------ETKDIVSDMETFQVINSESRHNGKYKCLAENEIGKSFSRETALVTVNEAPSIITQHKNRKVFLSYSDLPQSISFTCEFRGQPLYEARWRYGNEKIPPSSQDFKIEDHRNISNERISQIFTKLTIDLYSRTFSQQTSLRSSPNGRYNCEADNRHGIASLDYFLXXXXXXXXXXNIRHRKIAASLNQNVVMIRCQAESISTMHIKWYKTNEHIVLPFQSKKYSIFEAEVTKYEPERDLFTPGLKVNELTIKDLENDDFSNYSCVASNDQGIKKVNFEV 2288 F+ P++ V N+TL C Y Y IK + + F P S S I+ L I N+ + + G Y+C + ++ V + P IS I E + + + C++ G P P+ +K ++ N P T+ ++ + R L++ G C A N AG K TS+ + P I+ ++ + + L C P +I W L S+KF A + P + G IC A N G K VQL V P + D V + C S PPP I W K +S + L S K+ + S +GMY CV NI N +++ L+V PK GN+ I + G++ I C+ G P P + W + S T + + G Y C A N G + T + V E PS+ Q I F C +G P +W + ++ I + + L I S+ NG Y C A N G Y L + P + + H + L + + C+ E + I WYK + I + S + ++ K LF + +D YSC A N G + +F V Sbjct: 795 FIQEPSDVAVEIGSNVTLPC--------YVQGYPEPKIKWRRLDNMPVFSR-------PFSVSFISQLRTGALFISNLWASDKGTYICEAENQFGKIQSQTTVTVTGLVAPLIGISPSMASVI----EGQPLTLPCTLLAGNPIPE-------RRWMKNSAMLVQN-PYITVRSDGSLHIERVR-LQDGGKYTCVASNVAGTNNKTTSVA-VHVLPSIQ-HGQQILSTIEGVPVTLPCRASGIPKPSITWSKKGELISTSSAKFSAGADGSLYVVSPGSEESGEYICTATNAAGYAKRKVQLTVYVRPRVFGDQRGLSQDKPVEISVLAGEEAILPCEAKSLPPP-IITWAKDSQLISPFSPRHTFLPSGSMKITETRV--SDSGMYLCVATNIA---------GNVTQSVKLSVHVPPKIQH--GNRHIKVQVGQRVDILCNAH----GSPPPVITWFKSGRPFLDGAQHPGSPDGTLSIEQAVISDAGVYTCAATNIAGSDEAEVT--LHVQEPPSVEDLQPPFNTPFQERLANQRIEFPCPAKGTPKPTIKWLHNGREVTGQEPGVSILEDGAL-----------LVI----------ASVTPHNNGEYICVAVNEAGTTERKYNL-KVHVPPVIRDKEHVTNVSVLTSQLASLYCEVEGTPSPVITWYK--DDIQVTESSTVQIVNNGKILK------LF------------KVSAEDAGRYSCKAINIAGTSQKDFSV 1445 HSP 10 Score: 75.0998 bits (183), Expect = 6.531e-13 Identity = 120/526 (22.81%), Postives = 198/526 (37.64%), Query Frame = 3 Query: 822 NAMINQTIDLSCEVYANPAATIQW-------------VIMQGLQIIDSSKFIAKIRPDMDGPLICEAKNYLGSTKETVQLNVLRDPLIHIDSNYRVPK------NSNYSINCRVTSNPPPEFIKWYKLSN--MTDSSAVLISDDAKLNFILIDRSSTGMYACVTQNIQISTTGKRKPANSEKTMFLTVTYKPKEPQILG--NKIISIMKGEKFIIKCSTDRKSPGEPFPTLKWIDVETKD-------IVSDMETFQVINSESRHNGKYKCLAENEIGKSFSRETALVTVNEAPSIITQHKNRKVFLSYSDLPQSISFTCEFRGQPLYEARWRYGNEKIPPSSQDFKIEDHRNISNERISQIFTKLTIDLYSRTFSQQTSLRSSPNGRYNCEADNRHGIASLDYFLXXXXXXXXXXNIRHRKIAASLNQNVVMIRCQAESISTMHIKWYKTNEHIVLPFQSKKYSIFEAEVTKYEP-ERDLFTPGLKVNELTIKDLENDDFSNYSCVASNDQGIKKVNFEVVFKSQP 2306 + +IN + L CE A P T+ W +I+ G +++ I + + + G C A N G ++VL P+I +N +P+ N + + C + NP P W K + D SD L + + TG Y CV +N A S K F + P P ++G ++ +S++ + C G P P L W+ E V T Q+I ++ G Y C+A N+ G+S ++ +TV+ PSI H ++ + + S+S CE P W N ++ P S + +I + R +++ S G+Y C A N G ++ L + PP I+ ++ N V + C A I I W K ++ I +P E + + G K L I + + NY+CVASN +G + NF + + P Sbjct: 2787 DVIINNPLSLHCETNAAPPPTLTWYKDGRPLTSSDRVLILPGGRVLQ----IPRAKVEDAGRYTCVAVNEAGEDSLRYDVHVLLPPVIK-GANSDLPEEVTVLVNKSTQMECSSSGNPAPRNY-WQKDGQILLEDEHHKFQSDGRSLQILNAQITDTGRYVCVAENT----------AGSAKKYFNLNVHVP--PSVIGPNHEHLSVVVNHFISLNCEVS----GFPPPDLSWLKNEEPIKPNTNVLTVPGGRTLQIIRAKISDGGDYTCIAINQAGES--KKKVSLTVHVPPSI-KDHGSQSLSIVNVREGTSVSLECESNAVPPPVITWSK-NGRMIPDSTNVEILTGGQTLHIRRAEV---------------------SDTGQYVCRAINVAGRDDKNFHLNVYVPPTIEG--PETEVIVETISNPVTLTCDATGIPPPTITWLKNHKPI----------------ENSDPLEVHILSGGSK---LQIARPQRSNSGNYTCVASNMEGKAQKNFILFIQVPP 3244 HSP 11 Score: 71.2478 bits (173), Expect = 9.738e-12 Identity = 100/441 (22.68%), Postives = 173/441 (39.23%), Query Frame = 3 Query: 345 ISHESRLTIHNISSDNSGYYVCRVTLLTTSEHIISLAVVTVKTPPKSISFHFNKSINVFQEQEFIAIQCSVSGGIPPPKISMYIVKDNAIKRLKIISSNFPNSTIAEVSAISLWRPHYLENRGFVMCTAINDAGVLTKNTSLLNIKYKPKIKPFVPNTVNAMINQTIDLSCEVYANPAATIQW-----VIMQGLQIID--SSKFIAKIRPDMDGPLICEAKNYLGSTKETVQLNVLRDPLIHID--SNYRVPKNSNYSINCRVTSNPPPEFIKW-YKLSNMTDSSAVLISDDAKLNFILIDRSSTGMYACVTQNIQISTTGKRKPANSEKTMFLTVTYKPKEPQILGNKIISIM-KGEKFIIKCSTDRKSPGEPFPTLKW------IDVETKDIVSDMETFQVINSESRHNGKYKCLAENEIGKSFSRETALVTVNEAPSI 1616 I + L I D++G Y C + + + +TV PP+ S + ++N E + C V+ GIP P I + KD ++ +N A+ + LE+ G C A N AG T+ +L + P P ++ + + LSC+ P + W +I I+ S I K+ + G +C A+N +G K + V P+ D SN+ P N +NC V +P P I+W K +++ S + + L G Y CV N + E++M LT+ P I + +++ G + I+ C ++ GEP PT+ W I + + + + + + +Y+C+A N +G R +V V+ S+ Sbjct: 4126 ILNSGALQIAFAQPDDAGQYTCMAANM--AGSSSVSSTLTVHVPPRIQSTEVHFTVN---ENSQAVLPC-VADGIPTPAI--HWEKDG------VLIANLLGKYTAQPYGELILENVVLEDSGTYTCVANNAAGEDTRIVTLA-VHTLPTFTEL-PGDLSLNKGEQLRLSCKAVGIPLPKLTWTFNNNIIPAHFDSINGHSELVIEKVSKEDSGTYVCTAENSVGFVKAIGFVYVKEPPVFKGDYPSNWIEPLGGNAILNCEVKGDPAPT-IQWSRKGADIEISHRIRQLGNGSLAIYGTVNEDAGDYTCVAAN---------EAGMVERSMSLTLQ---SSPIITLEPVETVVDAGGRVILDC----QAAGEPQPTITWSRQGQPISWDNRLSMLPNSSLYIAAARKEDTSEYECVARNLMGSVLVRVPVIVQVHGGFSL 4533 HSP 12 Score: 66.6254 bits (161), Expect = 2.487e-10 Identity = 93/431 (21.58%), Postives = 171/431 (39.68%), Query Frame = 3 Query: 699 LENRGFVMCTAINDAGVLTKNTSLLNIKYKPKIKPFVPNTVNAMINQTIDLSCEVYANPAATIQWV-IMQGLQIIDSSKF--IAKIRPDMDGPLICEAKNYL-------GSTKETVQLNVLRDPLIHIDSNYRVPKNSNY------SINCRVTSNPPPEFIKWYKLSNMTDSSAVLISDDAKLNFILIDRSSTGMYACVTQNIQISTTGKRKPANSEKTMFLTVTYKPKEPQILGNKIISIMKGEKFIIKCSTDRKSPGEPFPTLKWI--DVETK-----DIVSDMETFQVINSESRHNGKYKCLAENEIGKSFSRETALVTVNEAPSIITQHKNRKVFLSYSDLPQSISFTCEFRGQPLYEARWRYGNEKIPPSSQDFKIEDHRNISNERISQIFTKLTIDLYSRTFSQQTSLRSSPNGRYNCEADNRHG 1922 L + GF C A++ AG + + ++ P I PN V + L+C V + + W + +++ DS++ +A + ++ I +A Y GS +V L V P + + +PKN ++ SI C T P P+ + + S ++ + L G YAC+ N ++T L PK ++ + + G+ +++C K+ G P P +KW D+E + I + ++ ++ G Y C+A NE G++ R T + V P I + + V ++ +++ C +G P + +WR + +P S+ F + IS R +F ++L +S G Y CEA+N+ G Sbjct: 491 LSDEGFYDCIAVSSAGT-GRAQTFFDVSEPPPIIQL-PNNVTVTPGERAVLACLVISAVDYNLTWQRSGRDIRLADSARIRTLANLSLELRSVKIGDAGEYRCVVSSEGGSAAASVFLTVQEKPKVTV-----MPKNQSFTGGSEISIMCSATGYPKPKIVWTMNEMFIMGSHRYRMTSEGTLFIKNAVPKDAGTYACLASNAA---------GTDKQTSTLRYIEAPK--LVVEQSELLVALGDTTVMEC----KTSGIPPPQVKWFKGDLELRPSTFLSIDPLVGLLKIQETQDLDAGDYTCVAINEAGRATGRLT--LDVGSPPVFIQEPSDVAV-----EIGSNVTLPCYVQGYPEPKIKWRR-LDNMPVFSRPFSVS---FISQLRTGALFI--------------SNLWASDKGTYICEAENQFG 874 HSP 13 Score: 55.4546 bits (132), Expect = 6.277e-7 Identity = 84/365 (23.01%), Postives = 143/365 (39.18%), Query Frame = 3 Query: 702 ENRGFVMCTAINDAGVLTKNTSLLNIKYKPKIKPF-VPNTVNAMINQTIDLSCEVYANPAATIQW-------VIMQGLQIIDSSKF--IAKIRPDMDGPLICEAKNYLGSTKETVQLNVLRDP-LIHID--SNYRVPKNSNYSINCRVTSNPPPEFIKWYKLSNMTDSS--AVLISDDAKLNFILIDRSSTGMYACVTQNIQISTTGKRKPANSEKTMFLTVTYKPKEPQILGNKIISIMKGEKFIIKCSTDRKSPGEPFPTLKW-----IDVETKDIVSDMETFQVINSESRH---NGKYKCLAENEIGKSFSRETALVTVNEAPSIITQHKNRKVFLSYSDLPQSISFTCEFRGQPLYEARWR 1727 E+ G C A N+AG ++K+ +L + P I P V+ ++N ++LSC PA I W + + +Q ++ ++ + + G C A + G + + V P + +D ++ V +N ++ C+ + PPP I W K ++ ++S L D T Y CV NI TT + LTV P G + + + + ++C ++ G P P + W + E+ S +E ++ ES H G+Y C+A N G R + V+ PSI N V ++ + CE G P WR Sbjct: 3498 EDTGKYTCVATNEAGEVSKHF-VLKVLEPPHINGSEGPGEVSVIVNNPLELSCIASGIPAPKISWMKDGRPFLQTEQVQTLEGGAILRVSSAQVEDTGRYTCLASSPAGDDDKEYLVRVHVPPNIAGMDEAQDFTVLRNRQVTLECKSDAVPPP-VIMWLKNREQLQATPRVRILSGGRYLQINNADLGDTANYTCVASNIAGKTT---------REFNLTVNVPPSIGG--GPQSLVTLLNKSIALEC----RAEGVPAPRITWRKDGVVLAESHARYSILEN-GFLHIESAHVTDTGRYLCMATNVAGT--DRRRIDLQVHVPPSIAMGPTNVTVTVN-----VQTTLACEATGIPKPSVTWR 3837
BLAST of hemicentin-1 isoform X2 vs. Ensembl Mouse
Match: Robo2 (roundabout guidance receptor 2 [Source:MGI Symbol;Acc:MGI:1890110]) HSP 1 Score: 101.679 bits (252), Expect = 3.972e-21 Identity = 145/630 (23.02%), Postives = 238/630 (37.78%), Query Frame = 3 Query: 810 PNTVNAMINQTIDLSCEVYANPAATIQWVI-------------MQGLQIIDSSKFIAKI------RPDMDGPLICEAKNYLG---STKETVQLNVLRDPLIHIDSNYRVPKNSNYSINCRVTSNPPPEFIKWYKLSNMTDSSAVLIS-DDAKLNFILIDRSSTGMYACVTQNIQISTTGKRKPANSEKTMFLTVTYKPKEPQILGNKIISIMKGEKFI-IKCSTDRKSPGEPFPTLKWIDVETKDI------VSDMETFQVINSESRHNGKYKCLAENEIGKSFSRETALVTVNEAPSIITQHKNRKVFLSYSDLPQSISFTCEFRGQPLYEARWRYGNEKIPPSSQDFKIEDHRNISNERISQIFT-KLTIDLYSRTFSQQTSLRSSPNGRYNCEADNRHG--IASLDYFLXXXXXXXXXXNIRHRKIAASLN-QNVVMIRCQAESISTMHIKWYKTNEHIVLPFQSKKYSIFEAEVTKYEPERDLFTPGLKVNELTIKDLENDDFSNYSCVASNDQGIKKVNFEVVFK---------------SQPDPPYDLRVTDFEWDSVTINWKPGFNGGLTQN-YEILVISENFGTQNVPFYSDKNENTLTITGLYPSTPYEIRIYAVNSIGRS 2549 P+ V + L+C+ P TI+W + + S F +I +PD +G +C A+NYLG S ++++ +LRD ++ V + C+ P I W K D IS KL +S GMY CV N+ G+R +E T+F + P L I ++ E+ + +C G+P PT++W + D+ + D T ++ + S G Y C+AEN +GK +A +TV P + + +++ V ++++F CE +G P W+ SQ+ + N R S T LTI T+++ S G Y C+A G +A + I I +L +++C+A I W K E + + +I + L IK+L D Y+CVA++ G + ++ V P PP +VTD +SVT++W+PG G L + Y I S++ + T+ GL P+T Y + A+N G S Sbjct: 37 PSDVIVSKGEPTTLNCKAEGRPTPTIEWYKDGERVETDKDDPRSHRMLLPSGSLFFLRIVHGRRSKPD-EGSYVCVARNYLGEAVSRNASLEVALLRDDFRQNPTDVVVAAGEPAILECQPPRGHPEPTIYWKKDKVRIDDKEERISIRGGKLMISNTRKSDAGMYTCVGTNM----VGERDSDPAELTVF-------ERPTFLRRPINQVVLEEEAVEFRCQVQ----GDPQPTVRW-KKDDADLPRGRYDIKDDYTLRIKKAMSTDEGTYVCIAENRVGK--VEASATLTVRAPPQFVVRPRDQIVAQG-----RTVTFPCETKGNPQPAVFWQK------EGSQNLLFPNQPQQPNSRCSVSPTGDLTI----------TNIQRSDAGYYICQALTVAGSILAKAQLEVTDVLTDRPPPIILQGPINQTLAVDGTALLKCKATGEPLPVISWLK--EGFTFLGRDPRATIQDQ------------------GTLQIKNLRISDTGTYTCVATSSSG--ETSWSAVLDVTESGATISKNYDMNDLPGPPSKPQVTDVSKNSVTLSWQPGTPGVLPASAYIIEAFSQSVSNSWQTVANHVKTTLYTVRGLRPNTIYLFMVRAINPQGLS 604 HSP 2 Score: 63.5438 bits (153), Expect = 2.023e-9 Identity = 99/454 (21.81%), Postives = 167/454 (36.78%), Query Frame = 3 Query: 360 RLTIHNISSDNSGYYVC--RVTLLTTSEHIISLAVVTVKTPPKSISFHFNKSINVFQEQEFIAIQCSVSGGIPPPKISMYIVK---DNAIKRLKIISSNFPNSTIAEVSAISLWRPHYLENRGFVMCTAINDAGVLTKNTSLLNIKYKPKIKPFVPNTVNAMI--NQTIDLSCEVYANPAATIQWV-----IMQGLQII--DSSKFIAKIRPDMDGPLICEAKNYLGSTKETVQLNVLRDPLIHIDSNYR-VPKNSNYSINCRVTSNPPPEFIKWYKLSNMT---------DSSAVLISDDAKLNFILIDRSSTGMYACVTQNIQISTTGKRKPANSEKTMFLTVTYKPKEPQILGNKIISIMKGEKFIIKCSTDRKSPGEPFPTLKWI-------DVETKDIVSDMETFQVINSESRHNGKYKCLAENEIGKSFSRETALVTVNEAPSIITQH 1628 R+ S + G YVC R L SL V ++ F N + V E ++C G P P I K D+ +R+ I S + A G C N G + + L + +P F+ +N ++ + ++ C+V +P T++W + +G I D + I K +G +C A+N +G + + L V P + + V + + C NP P W K + +S +S L I RS G Y C + S K A E T LT P Q N+ +++ ++KC K+ GEP P + W+ + + + D T Q+ N G Y C+A + G+ + +A++ V E+ + I+++ Sbjct: 94 RIVHGRRSKPDEGSYVCVARNYLGEAVSRNASLEVALLRD-----DFRQNPTDVVVAAGEPAILECQPPRGHPEPTIYWKKDKVRIDDKEERISIRGGKLMISNTRKSDA------------GMYTCVGTNMVGERDSDPAELTVFERPT---FLRRPINQVVLEEEAVEFRCQVQGDPQPTVRWKKDDADLPRGRYDIKDDYTLRIKKAMSTDEGTYVCIAENRVGKVEASATLTVRAPPQFVVRPRDQIVAQGRTVTFPCETKGNPQPAVF-WQKEGSQNLLFPNQPQQPNSRCSVSPTGDLTITNIQRSDAGYYICQALTVAGSILAK---AQLEVTDVLTDRPPPIILQGPINQTLAV--DGTALLKC----KATGEPLPVISWLKEGFTFLGRDPRATIQDQGTLQIKNLRISDTGTYTCVATSSSGE--TSWSAVLDVTESGATISKN 515
BLAST of hemicentin-1 isoform X2 vs. UniProt/SwissProt
Match: sp|O89026|ROBO1_MOUSE (Roundabout homolog 1 OS=Mus musculus OX=10090 GN=Robo1 PE=1 SV=1) HSP 1 Score: 107.071 bits (266), Expect = 7.274e-22 Identity = 148/617 (23.99%), Postives = 246/617 (39.87%), Query Frame = 3 Query: 849 LSCEVYANPAATIQWVIMQGLQIIDSSK---------------FIAKI------RPDMDGPLICEAKNYLG---STKETVQLNVLRDPLIHIDSNYRVPKNSNYSINCRVTSNPPPEFIKWYK-LSNMTDSSAVLISDDAKLNFILIDRSSTGMYACVTQNIQISTTGKRKPANSEKTMFLTVTYKPKEPQILGNKIISIMKGEKFIIKCSTDRKSPGEPFPTLKWI--DVE---TKDIVSDMETFQVINSESRHNGKYKCLAENEIGKSFSRETALVTVNEAPSIITQHKNRKVFLSYSDLPQSISFTCEFRGQPLYEARWRY-GNEKIPPSSQDFKIEDHRNISNERISQIFTKLTIDLYSRTFSQQTSLRSSPNGRYNCEADNRHGIASLDYFLXXXXXXXXXXNIRHRKIAASLNQNV-----VMIRCQAESISTMHIKWYKTNEHIVLPFQSKKYSIFEAEVTKYEPERDLFTPGLKVNELTIKDLENDDFSNYSCVASNDQG-------IKKVNFEVVFKSQ--------PDPPYDLRVTDFEWDSVTINWKPGFNGGLT-QNYEILVISENFGTQNVPFYSDKNENTLTITGLYPSTPYEIRIYAVNSIG 2543 L+C+ P TI+W +G + +++ K F +I RPD +G IC A+NYLG S ++++ +LRD S+ V + C+ P I W K S + D + KL +S G Y CV N+ G+R+ +E LTV +P + N +++ +F KC ++ G+P PT++W D E ++ + D T ++ + G Y C+AEN +GK + +A +TV E P + + +++ V L ++++F CE G P WR G++ + F + ++ S +SQ LTI T+++ S G Y C+ N G +L + + R+ +NQ V +++ C A I W K + +++ Q + E+ V L I+ + D Y+C AS G I+ F V + P P VTD ++VT++W+P N G T +Y I S G+ + T I GL P+ Y + A N+ G Sbjct: 48 LNCKAEGRPTPTIEW--YKGGERVETDKDDPRSHRMLLPSGSLFFLRIVHGRKSRPD-EGVYICVARNYLGEAVSHNASLEVAILRDDFRQNPSDVMVAVGEPAVMECQPPRGHPEPTISWKKDGSPLDDKDERITIRGGKLMITYTRKSDAGKYVCVGTNM----VGERESEVAE----LTVLERPSFVKRPSNLAVTVDDSAEF--KC----EARGDPVPTVRWRKDDGELPKSRYEIRDDHTLKIRKVTAGDMGSYTCVAENMVGK--AEASATLTVQEPPHFVVKPRDQVVALG-----RTVTFQCEATGNPQPAIFWRREGSQNL-----LFSYQPPQSSSRFSVSQT-GDLTI----------TNVQRSDVGYYICQTLNVAGSIITKAYLEVTDVIADRPPPVIRQ--GPVNQTVAVDGTLILSCVATGSPAPTILWRK--DGVLVSTQDSRIKQLESGV------------------LQIRYAKLGDTGRYTCTASTPSGEATWSAYIEVQEFGVPVQPPRPTDPNLIPSAPSKPEVTDVSKNTVTLSWQPNLNSGATPTSYIIEAFSHASGSSWQTAAENVKTETFAIKGLKPNAIYLFLVRAANAYG 602 HSP 2 Score: 76.6406 bits (187), Expect = 1.579e-12 Identity = 100/450 (22.22%), Postives = 165/450 (36.67%), Query Frame = 3 Query: 1041 LIHIDSNYRVPKNSNYSINCRVTSNPPPEFIKWYKLSNMTDS------SAVLISDDAKLNFILI-----DRSSTGMYACVTQNIQISTTGKRKPANSEKTMFLTVTYKPKEPQILGNKIISIMKGEKFIIKCSTDRKSPGEPFPTLKW------IDVETKDIVSDMETFQVINSESRHNGKYKCLAENEIGKSFSRETALVTVNEAPSIITQHKNRKVFLSYSDLPQSISFTCEFRGQPLYEARWRYGNEKIPPSSQDFKIEDHRNISNERISQIFTKLTIDLYSRTFSQQTSLRSSPNGRYNCEADNRHGIASLDYFLXXXXXXXXXXNIRHRKIAASLNQNVVMIRCQAESISTMHIKWYKTNEHIVL-----PFQSKKYSIFEAEVTKYEPERDLFTPGLKVNELTIKDLENDDFSNYSCVASNDQG--IKKVNFEV--VFKSQPDP 2312 ++ S+ V K ++NC+ P P I+WYK ++ S ++ L F+ I R G+Y CV +N S + L ++ ++ + GE +++C R G P PT+ W +D + + I + + GKY C+ N +G+ S E A +TV E PS + + N V + S F CE RG P+ RWR + ++P S ++I D + +++ + G Y C A+N G A L ++ PP R + +A V +C+A I W + +L P S ++S+ + +LTI +++ D Y C N G I K EV V +P P Sbjct: 31 IVEHPSDLIVSKGEPATLNCKAEGRPTPT-IEWYKGGERVETDKDDPRSHRMLLPSGSLFFLRIVHGRKSRPDEGVYICVARNYLGEAVSHNA---SLEVAILRDDFRQNPSDVM------VAVGEPAVMECQPPR---GHPEPTISWKKDGSPLDDKDERITIRGGKLMITYTRKSDAGKYVCVGTNMVGERES-EVAELTVLERPSFVKRPSNLAVTVD-----DSAEFKCEARGDPVPTVRWRKDDGELPKSR--YEIRDDHTLKIRKVT----------------------AGDMGSYTCVAENMVGKAEASATLTVQEPPHFVVKPRDQVVALG---RTVTFQCEATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSVSQ------------------TGDLTITNVQRSDVGYYICQTLNVAGSIITKAYLEVTDVIADRPPP 416 HSP 3 Score: 58.5362 bits (140), Expect = 5.339e-7 Identity = 97/434 (22.35%), Postives = 155/434 (35.71%), Query Frame = 3 Query: 360 RLTIHNISSDNSGYYVC--RVTLLTTSEHIISLAVVTVKTPPKSISFHFNKSINVFQEQEFIAIQCSVSGGIPPPKISMYIVK---DNAIKRLKIISSNFPNSTIAEVSAISLWRPHYLENRGFVMCTAINDAGVLTKNTSLLNIKYKPKIKPFV--PNTVNAMINQTIDLSCEVYANPAATIQWVIMQG------LQIIDSSKF-IAKIRPDMDGPLICEAKNYLGSTKETVQLNVLRDPLIHIDSNYRVPK-NSNYSINCRVTSNPPPEFIKWYKLSNMT---------DSSAVLISDDAKLNFILIDRSSTGMYACVTQNIQISTTGKRKPANSEKTMFLTVTYKPKEPQILGNKIISIMKGEKFIIKCSTDRKSPGEPFPTLKW----IDVETKDI-VSDMET--FQVINSESRHNGKYKCLAENEIGKS 1568 R+ S + G Y+C R L H SL V ++ F N S + E ++C G P P IS D+ +R+ I I+ R + G +C N G + L + +P FV P+ + ++ + + CE +P T++W G +I D I K+ G C A+N +G + + L V P + +V + C T NP P I W + + SS +S L + RS G Y C T N+ S K A E T + P Q N+ +++ I+ C G P PT+ W + V T+D + +E+ Q+ ++ G+Y C A G++ Sbjct: 92 RIVHGRKSRPDEGVYICVARNYLGEAVSHNASLEVAILRD-----DFRQNPSDVMVAVGEPAVMECQPPRGHPEPTISWKKDGSPLDDKDERITIRGGKL---------MITYTR---KSDAGKYVCVGTNMVGERESEVAELTVLERPS---FVKRPSNLAVTVDDSAEFKCEARGDPVPTVRWRKDDGELPKSRYEIRDDHTLKIRKVTAGDMGSYTCVAENMVGKAEASATLTVQEPPHFVVKPRDQVVALGRTVTFQCEATGNPQPA-IFWRREGSQNLLFSYQPPQSSSRFSVSQTGDLTITNVQRSDVGYYICQTLNVAGSIITK---AYLEVTDVIADRPPPVIRQGPVNQTVAV--DGTLILSCVAT----GSPAPTILWRKDGVLVSTQDSRIKQLESGVLQIRYAKLGDTGRYTCTASTPSGEA 495
BLAST of hemicentin-1 isoform X2 vs. UniProt/SwissProt
Match: sp|Q9NR99|MXRA5_HUMAN (Matrix-remodeling-associated protein 5 OS=Homo sapiens OX=9606 GN=MXRA5 PE=1 SV=3) HSP 1 Score: 107.071 bits (266), Expect = 8.470e-22 Identity = 180/793 (22.70%), Postives = 310/793 (39.09%), Query Frame = 3 Query: 363 LTIHNISSDNSGYYVCRVTLLTTSEHIISLAVVTVKTPPKSISFHFNKSINVFQEQEFIAIQCSVSGGIPPPKISMYIVKDNAIKRLKIISSNFPNSTIAEVSAISLWRPHYLENRGFVMCTAINDAGVLTKNTSLLNIKYKPKIKPFVPNTVNAMINQTIDLSCEVYANPAATIQWVIMQGLQIIDS-------------SKFIAKIRPDMDGPLICEAKNYLGSTKETVQLNVLRDPLIHIDSNYRV----PKNSN------YSINCRVTSNPPPEFIKWYKLSNMTDSSAVLISDDAKL----NFILIDRSST----GMYACVTQNIQISTTGKRKPANSEKTMFLTVTYKPKEPQILGNKIISIMKGEKFIIKCSTDRKSPGEPFPTLKWIDVETKDIVSDMET---------FQVINSES--------RHNGKYKCLAENEIGKSFSRETALVTVNEAPSIITQHKNRKVFLSYSDLPQSISFTCEFRGQPLYEARW-RYGNEKIPPSSQDFKIEDHRNISNERISQIFTKLTIDLYSRTFSQQTSLRSSPNGRYNCEADNRHGIASLDYFLXXXXXXXXXXN-----IRHRKIAASLNQNVVMIRCQAESISTMHIKWYKTNEHIVLPFQSKKYSIFEAEVTKYEPERDLFTPGLKVNELTIKDLENDDFSNYSCVASNDQGIKKVNFEV-VFKSQPDP----PYDLRVTDFEWDSVTINWKPGFNGGLTQNYEILVISENF-----GTQNVPFYSDKNENTLTITGLYPSTPYEIRIYAVNSIGRS 2549 L I + + G Y+C + L + ++ L VTV+ P + ++ H+ + + V+ + IA++C ++ G P P+IS +I D + + +S T+ E +S+ + +RG C A N AG + L P I ++ +I + C A P +++WV+ G QI S + +I + P G C A N +GS + TVQLNV R +N R+ P+ ++ ++C + +P P + M D+ L S D+++ N L+ +S T G Y CV +N K + + + V KP + + + G + C G P P + W + + S M++ + V N+ + R G Y C AEN++GK R V V AP+ I V + Y D+ ++ CE +G+P+ + W N+ IP SS+ + QI+ T+ + Q + RS +G Y C N G ++ + P R+IAA ++ +I C+AE I T + W E +VLP + +T + L I+ L D C+A N+ G ++ ++ V + P P ++T ++++N + T ++ + N G Q FY K + L I+GL R A N+ G + Sbjct: 1913 LVIRKVQVQDRGQYMCTASNLHGLDRMVVLLSVTVQQP-QILASHY-QDVTVYL-GDTIAMEC-LAKGTPAPQIS-WIFPDRRV--WQTVSPVEGRITLHENRTLSIKEASF-SDRGVYKCVASNAAGADSLAIRLHVAALPPVIHQEKLENISLPPGLSIHIHCTAKAAPLPSVRWVLGDGTQIRPSQFLHGNLFVFPNGTLYIRNLAPKDSGRYECVAANLVGSARRTVQLNVQR-----AAANARITGTSPRRTDVRYGGTLKLDCSASGDPWPRILWRLPSKRMIDA---LFSFDSRIKVFANGTLVVKSVTDKDAGDYLCVARN---------KVGDDYVVLKVDVVMKPAKIEHKEENDHKVFYGGDLKVDCVAT----GLPNPEISWSLPDGSLVNSFMQSDDSGGRTKRYVVFNNGTLYFNEVGMREEGDYTCFAENQVGKDEMR--VRVKVVTAPATIRNKTYLAVQVPYGDV---VTVACEAKGEPMPKVTWLSPTNKVIPTSSEKY--------------QIYQDGTLLI-------QKAQRSD-SGNYTCLVRNSAGEDRKTVWIHVNVQPPKINGNPNPITTVREIAAGGSRK--LIDCKAEGIPTPRVLW-AFPEGVVLP-----APYYGNRITVH-----------GNGSLDIRSLRKSDSVQLVCMARNEGGEARLILQLTVLEPMEKPIFHDPISEKITAMAGHTISLN----CSAAGTPTPSLVWVLPNGTDLQSGQQLQRFY-HKADGMLHISGLSSVDAGAYRCVARNAAGHT 2625 HSP 2 Score: 69.707 bits (169), Expect = 2.301e-10 Identity = 158/711 (22.22%), Postives = 261/711 (36.71%), Query Frame = 3 Query: 330 ESQITISHESR-LTIHNISSDNSGYYVCRVTLLTTSEHI-ISLAVVTVKTPPKSISFHFNKSINVFQEQEF-IAIQCSVSGGIPPPKISMYIVKDNAIKRLKIISSN---FPNSTIAEVSAISLWRPHYLEN-----RGFVMCTAINDAGVLTKNTSLLNIKYKP---KIKPFVPNTVNAMINQTIDLSCEVYANPAATIQWVIMQG------------LQIIDSSKFIAKIRPDMD-GPLICEAKNYLGSTKETVQLNVLRDP--LIHIDSN-YRVPKNSNYSINCRVTSNPPPEFIKWYKLSNMTDSSAV---LISDDAK-------------LNFILIDRSSTGMYACVTQNIQISTTGKRKPANSEKTMFLTVTYKPKEPQILGNKI---ISIMKGEKFIIKCSTDRKSPGEPFPTLKWIDVETKDIVSDMETFQVIN--------SESRHNGKYKCLAENEIGKSFSRETALVTVNEAPSIITQHKN-----RKVFLSYSDLPQSISFTCEFRGQPLYEARWRYGNEKIPPSS-QDFKIEDHRNISNERISQIFTKLTIDLYSRTFSQQTSLRSSPNGRYNCEADNRHGIASLDYFLXXXXXXXXXXNIRHRKIA---ASLNQNVVMIRCQAESISTMHIKWYKTNEHIVLPFQSKKYSIFEAEVTKYEPERDLFTPGLKVNELTIKDLENDDFSNYSCVASNDQG 2264 E +IT+ HE+R L+I S + G Y C + ++ + I L V + PP H K N+ I I C+ P P + + I+ + + N FPN T+ Y+ N G C A N G + T LN++ +I P + T+ L C +P I W + +++ + + K D D G +C A+N +G ++++V+ P + H + N ++V + ++C T P PE I W ++ D S V + SDD+ L F + G Y C +N GK + + VT P + NK + + G+ + C ++ GEP P + W+ K I + E +Q+ ++ +G Y CL N G+ R+T + VN P I + N R++ S C+ G P W + + P+ +I H N S +D+ SLR S + + C A N G A L L + ++ I H I+ ++ + + + C A T + W VLP + S ++ ++ + D G+ L I L + D Y CVA N G Sbjct: 1999 EGRITL-HENRTLSIKEASFSDRGVYKCVASNAAGADSLAIRLHVAAL--PP---VIHQEKLENISLPPGLSIHIHCTAKAA-PLPSVRWVLGDGTQIRPSQFLHGNLFVFPNGTL------------YIRNLAPKDSGRYECVAANLVGS-ARRTVQLNVQRAAANARITGTSPRRTDVRYGGTLKLDCSASGDPWPRILWRLPSKRMIDALFSFDSRIKVFANGTLVVKSVTDKDAGDYLCVARNKVGDDYVVLKVDVVMKPAKIEHKEENDHKVFYGGDLKVDCVATGLPNPE-ISW----SLPDGSLVNSFMQSDDSGGRTKRYVVFNNGTLYFNEVGMREEGDYTCFAEN----QVGK----DEMRVRVKVVT----APATIRNKTYLAVQVPYGDVVTVAC----EAKGEPMPKVTWLSPTNKVIPTSSEKYQIYQDGTLLIQKAQRSDSGNYTCLVRNSAGE--DRKTVWIHVNVQPPKINGNPNPITTVREIAAGGS----RKLIDCKAEGIPTPRVLWAFPEGVVLPAPYYGNRITVHGNGS------------LDIR--------SLRKSDSVQLVCMARNEGGEARL--ILQLTVLEPMEKPIFHDPISEKITAMAGHTISLNCSAAGTPTPSLVW-------VLPNGTDLQS--GQQLQRFYHKAD----GM----LHISGLSSVDAGAYRCVARNAAG 2623
BLAST of hemicentin-1 isoform X2 vs. UniProt/SwissProt
Match: sp|Q9Y6N7|ROBO1_HUMAN (Roundabout homolog 1 OS=Homo sapiens OX=9606 GN=ROBO1 PE=1 SV=1) HSP 1 Score: 105.145 bits (261), Expect = 2.528e-21 Identity = 157/666 (23.57%), Postives = 264/666 (39.64%), Query Frame = 3 Query: 705 NRGFVMCTAINDAGVLTKNTSLLNIK-YKPKIKPFVPNTVNAMINQTIDLSCEVYANPAATIQWVIMQGLQIIDSSK---------------FIAKI------RPDMDGPLICEAKNYLG---STKETVQLNVLRDPLIHIDSNYRVPKNSNYSINCRVTSNPPPEFIKWYK-LSNMTDSSAVLISDDAKLNFILIDRSSTGMYACVTQNIQISTTGKRKPANSEKTMFLTVTYKPKEPQILGNKIISIMKGEKFIIKCSTDRKSPGEPFPTLKWI--DVE---TKDIVSDMETFQVINSESRHNGKYKCLAENEIGKSFSRETALVTVNEAPSIITQHKNRKVFLSYSDLPQSISFTCEFRGQPLYEARWRY-GNEKIPPSSQDFKIEDHRNISNERISQIFTKLTIDLYSRTFSQQTSLRSSPNGRYNCEADNRHGIASLDYFLXXXXXXXXXXNIRHRKIAASLNQNVV-----MIRCQAESISTMHIKWYKTNEHIVLPFQSKKYSIFEAEVTKYEPERDLFTPGLKVNELTIKDLENDDFSNYSCVASNDQG-------IKKVNFEVVFKSQ--------PDPPYDLRVTDFEWDSVTINWKPGFNGGLT-QNYEILVISENFGTQNVPFYSDKNENTLTITGLYPSTPYEIRIYAVNSIG 2543 + G + T+ ND L S L + + P+I P+ + + L+C+ P TI+W +G + +++ K F +I RPD +G +C A+NYLG S ++++ +LRD S+ V + C+ P I W K S + D + KL +S G Y CV N+ G+R+ +E LTV +P + N +++ +F KC ++ G+P PT++W D E ++ + D T ++ + G Y C+AEN +GK + +A +TV E P + + +++ V L ++++F CE G P WR G++ + F + ++ S +SQ LTI T+++ S G Y C+ N G +L + + R+ +NQ V ++ C A I W K + +++ Q + E V L I+ + D Y+C+AS G I+ F V + P P VTD ++VT++W+P N G T +Y I S G+ + T I GL P+ Y + A N+ G Sbjct: 39 DHGTPIPTSDNDDNSLGYTGSRLRQEDFPPRIVEH-PSDLIVSKGEPATLNCKAEGRPTPTIEW--YKGGERVETDKDDPRSHRMLLPSGSLFFLRIVHGRKSRPD-EGVYVCVARNYLGEAVSHNASLEVAILRDDFRQNPSDVMVAVGEPAVMECQPPRGHPEPTISWKKDGSPLDDKDERITIRGGKLMITYTRKSDAGKYVCVGTNM----VGERESEVAE----LTVLERPSFVKRPSNLAVTVDDSAEF--KC----EARGDPVPTVRWRKDDGELPKSRYEIRDDHTLKIRKVTAGDMGSYTCVAENMVGK--AEASATLTVQEPPHFVVKPRDQVVALG-----RTVTFQCEATGNPQPAIFWRREGSQNL-----LFSYQPPQSSSRFSVSQT-GDLTI----------TNVQRSDVGYYICQTLNVAGSIITKAYLEVTDVIADRPPPVIRQ--GPVNQTVAVDGTFVLSCVATGSPVPTILWRK--DGVLVSTQDSRIKQLENGV------------------LQIRYAKLGDTGRYTCIASTPSGEATWSAYIEVQEFGVPVQPPRPTDPNLIPSAPSKPEVTDVSRNTVTLSWQPNLNSGATPTSYIIEAFSHASGSSWQTVAENVKTETSAIKGLKPNAIYLFLVRAANAYG 641
BLAST of hemicentin-1 isoform X2 vs. UniProt/SwissProt
Match: sp|D3YXG0|HMCN1_MOUSE (Hemicentin-1 OS=Mus musculus OX=10090 GN=Hmcn1 PE=1 SV=1) HSP 1 Score: 103.219 bits (256), Expect = 1.302e-20 Identity = 168/689 (24.38%), Postives = 265/689 (38.46%), Query Frame = 3 Query: 363 LTIHNISSDNSGYYVCRVTLLTTSEHIISLAVVTVKTPPKSIS-FHFNKSINVFQEQEFIAIQCSVSGGIPPPKISMYIVKDNAIKRLKIISSNFPNSTIAEVSA---ISLWRPHYLENRGFVMCTAINDAGVLTKNTSLLNIKYKPKIKPFVPNT---VNAMINQTIDLSCEVYANPAATIQWVIMQGLQIIDSSKF----------IAKIRPDMDGPLICEAKNYLGSTKETVQLNVLRDPLIHI-DSNYRVPKNSN-YSINCRVTSNPPPEFIKWYK----LSNMTDSSAVLISDDAKLNFILIDRSSTGMYACVTQNIQISTTGKRKPANSEKTMFLTVTYKPKEPQILGNKI---ISIMKGEKFIIKCSTDRKSPGEPFPTLKWI---------DVETKDIVSDMETFQVINSESRHNGKYKCLAENEIGKSFSRETALVTVN--EAPSIITQHKNRKVFLSYSDLPQSISFTCEFRGQPLYEARWRYGNEKIPPSSQDFKIEDHRNISNERISQIFTKLTIDLYSRTFSQQTSLRSSPNGRYNCEADNRHGIASLDYFLXXXXXXXXXXNIRHRKIAASLNQNVVMIRCQAESISTMHIKWYKTNEHIVLPFQSKKYSIFEAEVTKYEPERDLFTPGLKVNELTIKDLENDDFSNYSCVASNDQGIKKVNFEVVFKSQPDPPY 2318 L I N ++G YVC T+ + V PP I H + S+ V FI++ C VS G PPP +S ++ + IK PN+ + V + + R + + G C AIN AG K S L + P IK + VN ++ L CE A P I W G I DS+ I + G +C A N G + LNV P I ++ V SN ++ C T PPP I W K + N ++S +KL RS++G Y CV N++ GK A +F+ V P + G ++ +S++ GE + C+ D G P P L+W+ + E + +D T + + + GKY C+A N G+ E + +N P I + + ++ D SI+ C+ G P + W +P SS R +S ++ +I D+ Y C A NR G+ S Y L + PP + + +I + M C + + W + + + +A +T + T G+ L + E +D Y+CVA+N+ G +V+ V K +PP+ Sbjct: 2927 LQILNAQITDTGRYVCVAE--NTAGSAKKYFNLNVHVPPSVIGPNHEHLSVVV---NHFISLNCEVS-GFPPPDLS-WLKNEEPIK---------PNTNVLTVPGGRTLQIIRAK-ISDGGDYTCIAINQAGESKKKVS-LTVHVPPSIKDHGSQSLSIVNVREGTSVSLECESNAVPPPVITWS-KNGRMIPDSTNVEILTGGQTLHIRRAEVSDTGQYVCRAINVAGRDDKNFHLNVYVPPTIEGPETEVIVETISNPVTLTCDATGIPPPT-ITWLKNHKPIENSDPLEVHILSGGSKLQIARPQRSNSGNYTCVASNME----GK---AQKNFILFIQV-----PPSVAGAEVPSEVSVLLGENVELVCNAD----GIPTPHLQWLRDGKPIVNGETERVRVTTDGSTLNIYRALTSDMGKYTCVATNPAGE----EDRIFNLNVYVPPKIRGNKEEAEKLMALVD--TSINIECKATGTPPPQINWLKNGLPLPISSH------IRLLSAGQVVRIVRAQVSDI----------------AVYTCVASNRAGVDSKHYSLQVFVPPNMDNAMGTEEITIVKGSSTSMT-CFTDGTPAPSMSWLRDGQPLAP----------DAHLT-------VSTQGMV---LQLIKAETEDTGKYTCVATNEAG--EVSKHFVLKVL-EPPH 3527 HSP 2 Score: 103.219 bits (256), Expect = 1.554e-20 Identity = 154/697 (22.09%), Postives = 258/697 (37.02%), Query Frame = 3 Query: 315 VVPDSESQITISHESRLTIHNISSDNSGYYVCRVTLLTTSE----HIISLAVVTVKTPPKSISFHFNKSINVFQEQEFIAIQCSVSGGIPPPKISMYIVKDNAIKRLKIISSNFPNST--IAEVSAISLWRPHYLENRGFVMCTAINDAGVLTKNTSLLNIKYKPKIKPF-VPNTVNAMINQTIDLSCEVYANPAATIQWVIMQGLQIIDSSKFIAKIRPDMD------------GPLICEAKNYLGSTKETVQLNVLRDPLIHID----SNYRVPKNSNYSINCRVTSNPPPEFIKWYK--LSNMTDSSAVLISDDAKLNFILIDRSSTGMYACVTQNIQISTTGKRKPANSEKTMFLTVTYKPKEPQILGNKIISIMKGEKFIIKCSTDRKSPGEPFPTLKWIDVETKDIVSDME--------TFQVINSESRHNGKYKCLAENEIGKSFSRETALVTVNEAPSIITQHKNRKVFLSYSDLPQSISFTCEFRGQPLYEARWRYGNEKIPPSSQDFKIEDHRNISNERISQIFTKLTIDLYSRTFSQQTSLRSSPNGRYNCEADNRHGIASLDYFLXXXXXXXXXXNIRHRKIAASLNQNVVMIRCQAESISTMHIKWYKTNEHIVLPFQSKKYSIFEAEVTKYEPERDLFTPGLKVNELTIKDLENDDFSNYSCVASNDQGIKKVNFEVVFKSQP 2306 ++PDS + ++ L I ++G YVCR + + H+ T++ P + V + + C +G IPPP I+ +K K I ++ P ++ S + + RP N G C A N G KN +L I+ P + VP+ V+ ++ + ++L C P +QW + G I++ ++ D G C A N G LNV P I + +++ +I C+ T PPP+ I W K L S L+S + + S +Y CV N + K L V P +G + I+I+KG + C TD G P P++ W+ + + + D Q+I +E+ GKY C+A NE G+ S+ L V E P I +V + ++ + +C G P + W ++D R + T+ L + +S + GRY C A + G +Y + + PP I + N+ V + C+++++ I W K E + + P + + G L I + + D +NY+CVASN G F + P Sbjct: 3098 MIPDSTNVEILTGGQTLHIRRAEVSDTGQYVCRAINVAGRDDKNFHLNVYVPPTIEGP--------ETEVIVETISNPVTLTCDATG-IPPPTITW-------LKNHKPIENSDPLEVHILSGGSKLQIARPQR-SNSGNYTCVASNMEGKAQKNF-ILFIQVPPSVAGAEVPSEVSVLLGENVELVCNADGIPTPHLQW-LRDGKPIVNGETERVRVTTDGSTLNIYRALTSDMGKYTCVATNPAGEEDRIFNLNVYVPPKIRGNKEEAEKLMALVDTSINIECKATGTPPPQ-INWLKNGLPLPISSHIRLLSAGQVVRIVRAQVSDIAVYTCVASN---------RAGVDSKHYSLQVFVPPNMDNAMGTEEITIVKGSSTSMTCFTD----GTPAPSMSWLR-DGQPLAPDAHLTVSTQGMVLQLIKAETEDTGKYTCVATNEAGE-VSKHFVL-KVLEPPHINGSEGPGEVSVIVNN---PLELSCIASGIPAPKISW---------------MKDGRPF-------LQTEQVQTLEGGAILRVSSAQVEDTGRYTCLASSPAGDDDKEYLVRVHVPPNIAGMDEAQDFTVLRNRQVTL-ECKSDAVPPPVIMWLKNREQL-----------------QATPRVRILSGG---RYLQINNADLGDTANYTCVASNIAGKTTREFNLTVNVPP 3712 HSP 3 Score: 99.7525 bits (247), Expect = 1.688e-19 Identity = 151/698 (21.63%), Postives = 266/698 (38.11%), Query Frame = 3 Query: 315 VVPDSESQITI-SHESRLTIHNISSDNSGYYVC---RVTLLTTSEHIISLAVVTVKTPPKSISFHFNKSINVFQEQEFIAIQCSVSGGIPPPKISMYIVKDNAIKRLKIISSNFPNSTIAEVSAISLWRPHYLENRGFVMCTAINDAGVLTKNTSLLNIKYKPKI--KPFVPNTVNAMINQTIDLSCEVYANPAATIQWV-------IMQGLQIIDSSKFI--AKIRPDMDGPLICEAKNYLGSTKETVQLNVLRDPLIHIDS---NYRVPKNSNYSINCRVTSNPPPEFIKWYKLSNM--TDSSAVLISDDAKLNFILIDRSSTGMYACVTQNIQISTTGKRKPANSEKTMFLTVTYKPKEPQILGNKIISIMKGEKFIIKCSTDRKSPGEPFPTLKWIDVETK-------DIVSDMETFQVINSESRHNGKYKCLAENEIGKSFSRETALVTVNEAPSIITQHKNRKVFLSYSDLP----QSISFTCEFRGQPLYEARWRYGNEKIPPSSQDFKIEDHRNISNERISQIFTKLTIDLYSRTFSQQTSLRSSPNGRYNCEADNRHGIASLDY---------FLXXXXXXXXXXNIRHRKIAASLNQNVVMIRCQAESISTMHIKWYKTNEHIVLPFQSKKYSIFEAEVTKYEPERDLFTPGLKVNELTIKDLENDDFSNYSCVASNDQGIKKVNFEV 2288 V+ DS ++ I S RL I ++G Y C V + E+ + + + P + S I V + + I+++C V G IP P ++ ++ + + K + I + I + ++ + G +C A+N AG+ K L ++ P I VP V+ + ++ L+CE P +I W+ + ++I+ + + + RP+ G C +N G ++ L+VL P I ++ + ++ + + ++ C V NP P+ I W+K + D + ++S L S TG Y C+ NI K + +F++ T + +I I+ ++ C P T+ W T I+ T Q++N++ + G+Y C+A NE G+ V + P II + LS ++ S++ CE P RW Q K +DH +TI T Q + S GRY C A N G LD+ F + + R + + N + + C+ + + WYK P S +R L PG +V L I + +D Y+CVA N+ G + ++V Sbjct: 2236 VLADSAGRVHILSGGRRLQISIAEKADAGLYTCVASNVAGVAKKEYNLQVYI----RPSITNSGGHRPEITVIRGKS-ISLECEVQG-IPQPTVT-WMKDGRPLTKGKGVE-------ILDEGRILQLKNVHVSDTGRYVCVAVNVAGMTDKRYDL-SVHAPPSIIGNHGVPENVSVVEKSSVSLTCEASGIPLPSITWLKDGWPVNLGSSVKILSGGRMLRLMQTRPEDAGQYTCIVRNAAGEDRKMFGLSVLVPPHIVGENTLEDVKIKEKQSVTLTCEVRGNPVPQ-ITWHKDGQLLQEDEAHHMMSGGRFLQITNAQVSHTGRYTCLASNI-----AGDKSKSFRLNVFVSPTIAGVDSDGSPEDVIVILNSPTSLV-CEAYSYPPA----TITWFKDGTPLESNRNIRILPGGRTLQILNAQEDNAGRYSCVATNEAGEKIKHYEVKVYI---PPIIKKGDLLGPGLSPKEVKIRVNSSLTLECEAYAIPSASLRWYK-------DGQPLKSDDH--------------VTIAASGHTL-QIKEAQISDTGRYTCVASNLAGEDELDFDVNIQVPPSFQKLWEIGNMLDTGRSGEAKDVIINNPLSLHCETNAAPPPTLTWYKDGR----PLTSS--------------DRVLILPGGRV--LQIPRAKVEDAGRYTCVAVNEAGEDSLRYDV 2862 HSP 4 Score: 93.5893 bits (231), Expect = 1.305e-17 Identity = 152/679 (22.39%), Postives = 265/679 (39.03%), Query Frame = 3 Query: 363 LTIHNISSDNSGYYVCRVTLLTTSEHIISLAVVTVKTPPKSISFHFNKSINVFQEQEFIAIQCSVSGGIPPPKISMYIVKDNAIKRL------KIISSNFPNSTIAEVSAISLWRPHYLENRGFVMCTAINDAGVLTKNTSLLNIKYKPKIKPFVPNTVNAMINQTIDLSCEVYANPAATIQWVIMQGLQIIDSSKFIA-----------KIRPDMDGPLICEAKNYLGSTKETVQLNVLRDPLIHI-DSNYRVPKNSNYSINCRVTSNPPPEFIKWYKLSN-MTDSSAVLISDDAKLNFILIDRSSTGMYACVTQNIQISTTGKRKPANSEKTMFLTVTYKPKEPQILGNKI-ISIMKGEKFIIKCSTDRKSPGEPFPTLKW-------IDVETKDIVSDMETFQVINSESRHNGKYKCLAENEIGKSFSRET----ALVTVNEAPSIITQHKNRKVFLSYSDLPQSISFTCEFRGQPLYEARWRYGNEKIPPSSQDFKIEDHRNISNERISQIFTKLTIDLYSRTFSQQTSLRSSPNGRYNCEADNRHGIASLDYFLXXXXXXXXXXNIRHRKIAASLNQNVVMIRCQAESISTMHIKWYKTNEHIVLPFQSKKYSIFEAEVTKYEPERDLFTPGLKVNELTIKDLENDDFSNYSCVASNDQGIKKVNFEVVFKSQP 2306 L I + S D++ Y C VT + + +TV+ PP +I+ ++ ++ ++ A+ + G+P P I N ++ L +I+SS AI + L + G C A N AG ++ +L ++ P I+P P+ ++ ++N I L CE P I W +G+ +I S K +A +R D G +C A+N G+ V+LNV P+I Y V + S+ C +PPP+ I W+K + +T+S I + L G Y C+ N+ +S + LTV P+ I ++ ++ + + ++ C D G P P + W ++ K + N +G Y C+A N G+ T L T E P ++ +K ++ LS C+ G PL + W + N IP + I H + E++S+ +G Y C A+N G F+ +K PP+ K + I L N ++ C+ + I+W + I + + ++ L L I N+D +Y+CVA+N+ G+ + + + +S P Sbjct: 3860 LVIISPSVDDTASYECTVT--SDAGEDKRAVDLTVQVPP-TIA---DEPMDFLVTRQAPAVMTCSASGVPVPSIHW---TKNGLRLLPRGDGYRILSSG----------AIEIPTTQ-LNHAGRYTCVARNAAGSAHRHVTL-RVQEPPVIQP-QPSELDVILNNPILLPCEATGIPTPFITWQ-KEGINVITSGKSLAILPSGSLQISRAVRGDA-GTYMCVAQNPAGTALGKVKLNVQVPPVISSHQKEYVVTMDKPVSLLCETEGSPPPD-ITWHKDGHALTESIRQRILNSGALQIAFAQPDDAGQYTCMAANMA---------GSSSVSSTLTVHVPPR---IQSTEVHFTVNENSQAVLPCVAD----GIPTPAIHWEKDGVLIANLLGKYTAQPYGELILENVVLEDSGTYTCVANNAAGEDTRIVTLAVHTLPTFTELPGDLSLNKGEQLRLS-----------CKAVGIPLPKLTWTFNNNIIP--AHFDSINGHSELVIEKVSK----------------------EDSGTYVCTAENSVGFVKAIGFVYVKEPPVFKGDYPSNWIEP-LGGNAIL-NCEVKGDPAPTIQWSRKGADIEISHRIRQ---------------------LGNGSLAIYGTVNEDAGDYTCVAANEAGMVERSMSLTLQSSP 4439 HSP 5 Score: 90.5077 bits (223), Expect = 9.450e-17 Identity = 130/553 (23.51%), Postives = 217/553 (39.24%), Query Frame = 3 Query: 699 LENRGFVMCTAINDAGVLTKNTSL---LNIKYKPKIKPF---VPNTVNAMINQTIDLSCEVYANPAATIQWVIMQGLQII---DSSKFIAKIRPDM--------DGPLICEAKNYLGSTKETVQLNVLRDPLIHIDSNYR---VPKNSNYSINCRVTSNPPPEFIKWYKLSN--MTDSSAVLISDDAKLNFILIDRSSTGMYACVTQNIQISTTGKRKPANSEKTMFLTVTYKP--KEPQILGNKIISIMKGEKFIIKCSTDRKSPGEPFPTLKWI-------DVETKDIVSDMETFQVINSESRHNGKYKCLAENEIGKSFSRETALVTVNEAPSIITQHKNRKVFLSYSDLPQSISFTCEFRGQPLYEARWRYGNEKIPPSSQDFKIEDHRNISNERISQIFTKLTIDLYSRTFSQQTSLRSSPNGRYNCEADNRHGIASLDYFLXXXXXXXXXXNIRHRKIAASLNQNVVMIRCQAESISTMHIKWYKTNEHIVLPFQSKKYSIFEAEVTKYEPERDLFTPGLKVNELTIKDLENDDFSNYSCVASNDQG 2264 +E+ G C A+N+AG SL +++ P IK +P V ++N++ + C NPA W + QI+ + KF + R G +C A+N GS K+ LNV P + I N+ V N S+NC V+ PPP+ + W K +++ + + L I S G Y C+ N + S+K + LTV P K+ I+++ +G ++C ++ P P + W D +I++ +T + +E G+Y C A N G+ V V P I + + + S+ ++ TC+ G P W +++H+ I N ++ L + Q + S +G Y C A N G A ++ L I+ PP + +++ L +NV ++ C A+ I T H++W + + IV E ER T + L I D Y+CVA+N G Sbjct: 2839 VEDAGRYTCVAVNEAG----EDSLRYDVHVLLPPVIKGANSDLPEEVTVLVNKSTQMECSSSGNPAPRNYW--QKDGQILLEDEHHKFQSDGRSLQILNAQITDTGRYVCVAENTAGSAKKYFNLNVHVPPSV-IGPNHEHLSVVVNHFISLNCEVSGFPPPD-LSWLKNEEPIKPNTNVLTVPGGRTLQIIRAKISDGGDYTCIAIN---------QAGESKKKVSLTVHVPPSIKDHGSQSLSIVNVREGTSVSLECESNAVPP----PVITWSKNGRMIPDSTNVEILTGGQTLHIRRAEVSDTGQYVCRAINVAGRDDKNFHLNVYV---PPTIEGPETEVIVETISN---PVTLTCDATGIPPPTITW---------------LKNHKPIENSDPLEVHI-----LSGGSKLQIARPQRSNSGNYTCVASNMEGKAQKNFILFIQVPPSVAGAEVPSEVSVLLGENVELV-CNADGIPTPHLQWLRDGKPIV----------------NGETERVRVT--TDGSTLNIYRALTSDMGKYTCVATNPAG 3325 HSP 6 Score: 90.1225 bits (222), Expect = 1.313e-16 Identity = 162/689 (23.51%), Postives = 254/689 (36.87%), Query Frame = 3 Query: 348 SHESRLTIHNISSDNSGYYVCRVTLLTTSEHIISLAVVTVKTPP--KSISFHFNKSINVFQEQEFIAIQCSVSGGIPPPKISMYIVKDNAIKRLKIISSNFPNSTIAEVSAISLWRPHYLENRGFVMCTAINDAGVLTKNTSLLNIKYKPKI--KPFVPNTVNAMINQTIDLSCEVYANPAATIQW-------VIMQGLQIIDSSKFIA--KIRPDMDGPLICEAKNYLGSTKETVQLNVLRDPLI---HIDSNYRVPKNSNYSINCRVTSNPPPEFIKWYKLSN---MTDSSAVLISDDAKLNFILIDRSSTGMYACVTQNIQISTTGKRKPANSEKTMFLTVTYKPKEPQILGNKI---ISIMKGEKFIIKCSTDRKSPGEPFPTLKWIDVETKDIVSDMETFQVINSESRH--------NGKYKCLAENEIG---KSFSRETALVTVNEAPSI---ITQHKNRKVFLSYSDLPQSISFTCEFRGQPLYEARWRYGNEKIPPSSQDFKIEDHRNISNERISQIFTKLTIDLYSRTFSQQTSLRSSPNGRYNCEADNRHGIASLDYFLXXXXXXXXXXNIRHRKIAASLNQNVVMIRCQAESISTMHIKWYKTNEHIVLPFQSKKYSIFEAEVTKYEPERDLFTPGLKVNELTIKDLENDDFSNYSCVASNDQGIKKVNFEVVFKSQP 2306 S + L+I ++G Y C T + S+ + + V+ PP + + FN + I C G P P I + + ++ P +I E A+ + N G +C A+N+AG T+ L + P I K V N V+ + +Q L CEV P+ I W +QI+++ K + K+ + G C+A N G++++ +NVL P I S V N N ++ C T P P I W+K + D + L L+ RS G Y C N GK+ K + LTV Y P P I G I IS + ++C T G P P + W + + + S + + + H + Y C A N G KSF V + P+I +T N++V + QS+ C+ G P W + +P + D H +++ +I + L +D G+Y C A + G + Y + + PP ++ L N++ + CQ I W K + I ERD F L +L I + D Y CVA+N G + FEV P Sbjct: 1220 SPDGTLSIEQAVISDAGVYTCAATNIAGSDE--AEVTLHVQEPPSVEDLQPPFNTPFQERLANQRIEFPCPAKG-TPKPTIKW-------LHNGREVTGQEPGVSILEDGALLVIASVTPHNNGEYICVAVNEAGT-TERKYNLKVHVPPVIRDKEHVTN-VSVLTSQLASLYCEVEGTPSPVITWYKDDIQVTESSTVQIVNNGKILKLFKVSAEDAGRYSCKAINIAGTSQKDFSVNVLVPPSILGASSPSEVSVVLNHNVTLQCPGTGVPFPA-IHWFKDGKPLFLGDPNIELSDRGQSLHLRNARRSDKGRYQCTVSN----AAGKQA-----KDIKLTV-YVP--PSIKGGNITTEISALLNSIVKLECETR----GLPVPAITWYK-DGQVVTSSSQALYIDKGQLLHIQRAQVSDSATYTCHAANVAGTAEKSFH-----VDIYVPPTIEGDLTAPSNKQVIIG-----QSLILECKAAGNPPPILTWL--KDGVPVKASD---NIHIEAGGKKL-EILSALEVD----------------RGQYICVATSVAGEREIKYEVDVLVPPAVEGG-EETSYFIVLANNLLELDCQVSGSPPPTIMWLKGGQLI--------------------DERDGFKILLNGRKLVIAQAQVSDTGLYQCVATNIAGDHRKEFEVTVHVPP 1825 HSP 7 Score: 77.7962 bits (190), Expect = 8.212e-13 Identity = 175/741 (23.62%), Postives = 279/741 (37.65%), Query Frame = 3 Query: 159 PNNATVNSKENLTLEC-VVDQQNIVYSWEYKPFHIKSNIMSKVLGFCYFEKPCVVPDSESQITISHESRLTIHNISSDNSGYYVCRVTLLTTSEHIISLAVV--TVKTPPKSISFHFNKSINVFQEQEFIAIQCSVSGGIPPPKI-----SMYIVKDNAIKRLKIISSNFPNSTIAEVSAISLWRPHYLENRGFVMCTAINDAGVLTKNTSLLNIKYKPKIKPFVPNTVNAMINQTIDLSCEVYANPAATIQWVIMQGLQIIDSSKFIA--------KIRPDMD---GPLICEAKNYLGSTKETVQLNVLRDPL-IHIDSNYRVPKNSNYSINCRVTSNPPPEFIKWYKLSNMTDSS---AVLISDDAKLNFILIDR---SSTGMYACVTQNIQISTTGKRKPANSEKTMFLTVTYKPKEPQILG--NKIISIMKGEKFIIKCSTDRKSPGEPFPTLKWIDVETKDI------VSDMETFQVINSESRHNGKYKCLAENEIGKSFSRETALVTVNEAPSIITQHKNRKVFLSYSDLPQSISFTCEFRGQPLYEARWRYGNEKIPPSSQDFKIEDHRNISNERISQIFTKLTIDLYSRTFSQQTSLRSSPNGRYNCEADNRHGIASLDYFLXXXXXXXXXXNIRH----RKIAAS-LNQNVVMIRCQAESISTMHIKWYKTNEHIVLPFQSKKYSIFEAEVTKYEPERDLFTPGLKVNELTIKDLENDDFSNYSCVASNDQG 2264 PNN TV E L C V+ + +W+ I+ + DS T+++ S L + ++ ++G Y C V +SE + A V TV+ PK N+S F I+I CS + G P PKI M+I+ + R ++ S T+ +A+ ++ G C A N AG K TS L PK+ + A+ + T+ + C+ P ++W +G + S F++ KI+ D G C A N G + L+V P+ I S+ V SN ++ C V P P+ IKW +L NM S +V + + I S G Y C +N GK + S+ T+ +T P ++G + S+++G+ + C+ G P P +W+ + V + + + GKY C+A N G + +T V V+ PSI QH +++ + +P ++ C G P W E I SS F + LY S S +G Y C A N G A L + P + + R + + S L ++ C+A+S+ I W K + ++ PF R F P + I + D Y CVA+N G Sbjct: 526 PNNVTVTPGERAVLACLVISAVDYNLTWQRSGRDIR------------------LADSARIRTLANLS-LELRSVKIGDAGEYRCVV----SSEGGSAAASVFLTVQEKPKVTVMPKNQS---FTGGSEISIMCSAT-GYPKPKIVWTMNEMFIMGSH---RYRMTS----EGTLFIKNAVP-------KDAGTYACLASNAAGT-DKQTSTLRYIEAPKLVVEQSELLVALGDTTV-MECKTSGIPPPQVKW--FKGDLELRPSTFLSIDPLVGLLKIQETQDLDAGDYTCVAINEAGRATGRLTLDVGSPPVFIQEPSDVAVEIGSNVTLPCYVQGYPEPK-IKWRRLDNMPVFSRPFSVSFISQLRTGALFISNLWASDKGTYICEAEN----QFGKIQ---SQTTVTVTGLVAP----LIGISPSMASVIEGQPLTLPCTL---LAGNPIPERRWMKNSAMLVQNPYITVRSDGSLHIERVRLQDGGKYTCVASNVAGT--NNKTTSVAVHVLPSI--QH-GQQILSTIEGVP--VTLPCRASGIPKPSITWSKKGELISTSSAKFSAGADGS----------------LYV------VSPGSEESGEYICTATNAAGYAKRKVQLTVYVRPRVFGDQRGLSQDKPVEISVLAGEEAILPCEAKSLPPPIITWAK-DSQLISPFSP----------------RHTFLPS---GSMKITETRVSDSGMYLCVATNIAG 1157 HSP 8 Score: 77.7962 bits (190), Expect = 8.351e-13 Identity = 145/669 (21.67%), Postives = 246/669 (36.77%), Query Frame = 3 Query: 390 NSGYYVCRVTLLTTSEHIISLAVVTVKTPPKSISFHFNKSINVFQEQEFIAIQCSVSGGIPPPKISMYIVKDNAIKR---LKIISSNFPNSTIAEVSAISLWRPHYLENRGFVMCTAINDAGVLTKNTSLLNIKYKPKIKPFVPNTVNAMINQTIDLSCEVYANPAATIQWV--------IMQGLQIIDSSKF--IAKIRPDMDGPLICEAKNYLGSTKETVQLNVLRDPLIHIDSNYR---VPKNSNYSINCRVTSNPPPEFIKWYKLSN--MTDSSAVLISDDAKLNFILIDRSSTGMYACVTQNIQISTTGKRKPANSEKTMFLTVTYKPKEPQILGNK-IISIMKGEKFIIKCSTDRKSPGEPFPTLKWIDVETK--------DIVSDMETFQVINSESRHNGKYKCLAENEIGKSFSRETALVTVNEAPSIITQHKNRKVFLSYSDLPQSISFTCEFRGQPLYEARWRYGNEKIPPSSQDFKIEDHRNISNE---RISQIFTKLTIDLYSRTFSQQTSLRSSPNGRYNCEADNRHGIASLDYFLXXXXXXXXXXNIRHRKIAASLNQNVVMIRCQAESISTMHIKWYKTNEHIVLPFQSKKYSIFEAEVTKYEPERDLFTPGLKVNELTIKDLENDDFSNYSCVASNDQGIKKVNFEVVFKSQP 2306 + G Y+C T + I V V P ++ S + + + C VSG PPP I M++ I KI+ N IA+ + + G C A N AG K + + P IK + + + L C P +I W+ L+I S + IAK + G C A N G + QL+V P + R V N+ + C+ T P P I WYK S+ +SA + L S G+Y CV N A + + + + P P I G+ ++ ++ ++C ++ G P P+L W+ + I+S + +++ G+Y C+A N G+ R+ L V P+I+ + +N V + Q++ C+ ++ +PP + + ++D R + IS+ + L I+ ++ GRY CEA N G +Y + + PP I + ++ A + N++ + C++ I + W K +VL + + I L I E D Y+CVASN G+ K + + +P Sbjct: 1705 DRGQYICVATSVAGEREIKYEVDVLV---PPAVEGGEETSYFIVLANNLLELDCQVSGS-PPPTI-MWLKGGQLIDERDGFKILL-NGRKLVIAQAQ---------VSDTGLYQCVATNIAGDHRKEFEV-TVHVPPTIKSSDLPEKTVVRYKPVTLQCIANGIPNPSITWLKDDQPVNTAHGNLKIQSSGRVLQIAKALLEDAGRYTCVATNAAGEAHQHTQLHVHEPPSLDDAGKMRNETVVVNNPIQLECKATGKPLP-VITWYKDSHPLSGSASAAFLKRGQVLEIGSAQISDAGIYKCVAIN----------SAGATELFYSLQVHVP--PSISGSSSMVEVVVNNLARLEC----EARGIPAPSLTWLKDGSPVSSFSNGIQILSGGRILALTSAQMSDAGRYTCVAVNAAGEK-QRDIDL-RVYAPPNIMGEEQNVSVLIG-----QAVELFCQ--------------SDAVPPPTLMW-LKDGRPLLKRPGLSISENGSVLKIE----------DAQAGDTGRYTCEATNVAGKTEKNYNVNVWVPPSIYGSDELVQLTA-IEGNLITLLCESSGIPPPDLTWKKKGS-LVLADSAGRVHILSGG-----------------RRLQISIAEKADAGLYTCVASNVAGVAKKEYNLQVYIRP 2289 HSP 9 Score: 76.6406 bits (187), Expect = 1.708e-12 Identity = 165/743 (22.21%), Postives = 254/743 (34.19%), Query Frame = 3 Query: 147 FLITPNNATVNSKENLTLECVVDQQNIVYSWEYKPFHIKSNIMSKVLGFCYFEKPCVVPDSESQITISHESRLTIHNISSDNSGYYVCRV-TLLTTSEHIISLAVVTVKTPPKSISFHFNKSINVFQEQEFIAIQCSVSGGIPPPKISMYIVKDNAIKRLKIISSNFPNSTIAEVSAISLWRPHYLENRGFVMCTAINDAGVLTKNTSLLNIKYKPKIKPFVPNTVNAMINQTIDLSCEVYANPAATIQWVIMQGLQIIDSSKFIAK-------IRPDMD--GPLICEAKNYLGSTKETVQLNVLRDPLIHIDS---------NYRVPKNSNYSINCRVTSNPPPEFIKWYK----LSNMTDSSAVLISDDAKLNFILIDRSSTGMYACVTQNIQISTTGKRKPANSEKTMFLTVTYKPKEPQILGNKIISIMKGEKFIIKCSTDRKSPGEPFPTLKWIDV------ETKDIVSDMETFQVINSESRHNGKYKCLAENEIGKSFSRETALVTVNEAPSIITQHKNRKVFLSYSDLPQSISFTCEFRGQPLYEARWRYGNEKIPPSSQDFKIEDHRNISNERISQIFTKLTIDLYSRTFSQQTSLRSSPNGRYNCEADNRHGIASLDYFLXXXXXXXXXXNIRHRKIAASLNQNVVMIRCQAESISTMHIKWYKTNEHIVLPFQSKKYSIFEAEVTKYEPERDLFTPGLKVNELTIKDLENDDFSNYSCVASNDQGIKKVNFEV 2288 F+ P++ V N+TL C Y Y IK + + F P S S I+ L I N+ + + G Y+C + ++ V + P IS I E + + + C++ G P P+ +K ++ N P T+ ++ + R L++ G C A N AG K TS+ + P I+ ++ + + L C P +I W L S+KF A + P + G IC A N G K VQL V P + D V + C S PPP I W K +S + L S K+ + S +GMY CV NI N +++ L+V PK GN+ I + G++ I C+ G P P + W + S T + + G Y C A N G + T + V E PS+ Q I F C +G P +W + ++ I + + L I S+ NG Y C A N G Y L + P + + H + L + + C+ E + I WYK + I + S + ++ K LF + +D YSC A N G + +F V Sbjct: 795 FIQEPSDVAVEIGSNVTLPC--------YVQGYPEPKIKWRRLDNMPVFSR-------PFSVSFISQLRTGALFISNLWASDKGTYICEAENQFGKIQSQTTVTVTGLVAPLIGISPSMASVI----EGQPLTLPCTLLAGNPIPE-------RRWMKNSAMLVQN-PYITVRSDGSLHIERVR-LQDGGKYTCVASNVAGTNNKTTSVA-VHVLPSIQ-HGQQILSTIEGVPVTLPCRASGIPKPSITWSKKGELISTSSAKFSAGADGSLYVVSPGSEESGEYICTATNAAGYAKRKVQLTVYVRPRVFGDQRGLSQDKPVEISVLAGEEAILPCEAKSLPPP-IITWAKDSQLISPFSPRHTFLPSGSMKITETRV--SDSGMYLCVATNIA---------GNVTQSVKLSVHVPPKIQH--GNRHIKVQVGQRVDILCNAH----GSPPPVITWFKSGRPFLDGAQHPGSPDGTLSIEQAVISDAGVYTCAATNIAGSDEAEVT--LHVQEPPSVEDLQPPFNTPFQERLANQRIEFPCPAKGTPKPTIKWLHNGREVTGQEPGVSILEDGAL-----------LVI----------ASVTPHNNGEYICVAVNEAGTTERKYNL-KVHVPPVIRDKEHVTNVSVLTSQLASLYCEVEGTPSPVITWYK--DDIQVTESSTVQIVNNGKILK------LF------------KVSAEDAGRYSCKAINIAGTSQKDFSV 1445 HSP 10 Score: 75.485 bits (184), Expect = 3.675e-12 Identity = 184/829 (22.20%), Postives = 302/829 (36.43%), Query Frame = 3 Query: 21 GTLSTDNETYNLLSNR*-----NMEYFKTFILITLFGNLMD---RSYTLNFLITPNNATVNSK---ENLTLECVVDQQNIVYSWEYKPFHIKSNIMSKVLGFCYFEKPCVVPDSESQITISHESR-LTIHNISSDNSGYYVCRVTLLTTSEHIISLAVVTVKTP-------------PKSISFHFNKSINVFQEQEFIAIQCSVSGGIPPPKISMYIVKDNAIKRLKIISSNFPNSTIAEVSAISLWRPHYLENRGFVMCTAINDAGVLTKNTSLLNIKYKPKIKPF--VPNTVNA---------MINQTIDLSCEVYANPAATIQW-------------VIMQGLQIIDSSKFIAKIRPDMDGPLICEAKNYLGSTKETVQLNVLRDPLIHIDSNYRVPK------NSNYSINCRVTSNPPPEFIKWYKLSN--MTDSSAVLISDDAKLNFILIDRSSTGMYACVTQNIQISTTGKRKPANSEKTMFLTVTYKPKEPQILG--NKIISIMKGEKFIIKCSTDRKSPGEPFPTLKWIDVETKD-------IVSDMETFQVINSESRHNGKYKCLAENEIGKSFSRETALVTVNEAPSIITQHKNRKVFLSYSDLPQSISFTCEFRGQPLYEARWRYGNEKIPPSSQDFKIEDHRNISNERISQIFTKLTIDLYSRTFSQQTSLRSSPNGRYNCEADNRHGIASLDYFLXXXXXXXXXXNIRHRKIAASLNQNVVMIRCQAESISTMHIKWYKTNEHIVLPFQSKKYSIFEAEVTKYEP-ERDLFTPGLKVNELTIKDLENDDFSNYSCVASNDQGIKKVNFEVVFKSQP 2306 G L ++E ++++S N + T L N+ +S+ LN ++P A V+S E++ + + ++ Y P I +F+ + +S I I R L I N DN+G Y C V E I V P PK + N S+ + E E AI P S+ KD + LK + + TIA + + + G C A N AG + + NI+ P + + N ++ +IN + L CE A P T+ W +I+ G +++ I + + + G C A N G ++VL P+I +N +P+ N + + C + NP P W K + D SD L + + TG Y CV +N A S K F + P P ++G ++ +S++ + C G P P L W+ E V T Q+I ++ G Y C+A N+ G+S ++ +TV+ PSI H ++ + + S+S CE P W N ++ P S + +I + R +++ S G+Y C A N G ++ L + PP I+ ++ N V + C A I I W K ++ I +P E + + G K L I + + NY+CVASN +G + NF + + P Sbjct: 2516 GQLLQEDEAHHMMSGGRFLQITNAQVSHTGRYTCLASNIAGDKSKSFRLNVFVSPTIAGVDSDGSPEDVIVILNSPTSLVCEAYSYPPATIT-----------WFKDGTPL-ESNRNIRILPGGRTLQILNAQEDNAGRYSC-VATNEAGEKIKHYEVKVYIPPIIKKGDLLGPGLSPKEVKIRVNSSLTL--ECEAYAI----------PSASLRWYKDG--QPLK----SDDHVTIAASGHTLQIKEAQISDTGRYTCVASNLAGEDELDFDV-NIQVPPSFQKLWEIGNMLDTGRSGEAKDVIINNPLSLHCETNAAPPPTLTWYKDGRPLTSSDRVLILPGGRVLQ----IPRAKVEDAGRYTCVAVNEAGEDSLRYDVHVLLPPVIK-GANSDLPEEVTVLVNKSTQMECSSSGNPAPRNY-WQKDGQILLEDEHHKFQSDGRSLQILNAQITDTGRYVCVAENT----------AGSAKKYFNLNVHVP--PSVIGPNHEHLSVVVNHFISLNCEVS----GFPPPDLSWLKNEEPIKPNTNVLTVPGGRTLQIIRAKISDGGDYTCIAINQAGES--KKKVSLTVHVPPSI-KDHGSQSLSIVNVREGTSVSLECESNAVPPPVITWSK-NGRMIPDSTNVEILTGGQTLHIRRAEV---------------------SDTGQYVCRAINVAGRDDKNFHLNVYVPPTIEGP--ETEVIVETISNPVTLTCDATGIPPPTITWLKNHKPI----------------ENSDPLEVHILSGGSK---LQIARPQRSNSGNYTCVASNMEGKAQKNFILFIQVPP 3244 HSP 11 Score: 71.633 bits (174), Expect = 5.715e-11 Identity = 100/441 (22.68%), Postives = 173/441 (39.23%), Query Frame = 3 Query: 345 ISHESRLTIHNISSDNSGYYVCRVTLLTTSEHIISLAVVTVKTPPKSISFHFNKSINVFQEQEFIAIQCSVSGGIPPPKISMYIVKDNAIKRLKIISSNFPNSTIAEVSAISLWRPHYLENRGFVMCTAINDAGVLTKNTSLLNIKYKPKIKPFVPNTVNAMINQTIDLSCEVYANPAATIQW-----VIMQGLQIID--SSKFIAKIRPDMDGPLICEAKNYLGSTKETVQLNVLRDPLIHID--SNYRVPKNSNYSINCRVTSNPPPEFIKW-YKLSNMTDSSAVLISDDAKLNFILIDRSSTGMYACVTQNIQISTTGKRKPANSEKTMFLTVTYKPKEPQILGNKIISIM-KGEKFIIKCSTDRKSPGEPFPTLKW------IDVETKDIVSDMETFQVINSESRHNGKYKCLAENEIGKSFSRETALVTVNEAPSI 1616 I + L I D++G Y C + + + +TV PP+ S + ++N E + C V+ GIP P I + KD ++ +N A+ + LE+ G C A N AG T+ +L + P P ++ + + LSC+ P + W +I I+ S I K+ + G +C A+N +G K + V P+ D SN+ P N +NC V +P P I+W K +++ S + + L G Y CV N + E++M LT+ P I + +++ G + I+ C ++ GEP PT+ W I + + + + + + +Y+C+A N +G R +V V+ S+ Sbjct: 4126 ILNSGALQIAFAQPDDAGQYTCMAANM--AGSSSVSSTLTVHVPPRIQSTEVHFTVN---ENSQAVLPC-VADGIPTPAI--HWEKDG------VLIANLLGKYTAQPYGELILENVVLEDSGTYTCVANNAAGEDTRIVTLA-VHTLPTFTEL-PGDLSLNKGEQLRLSCKAVGIPLPKLTWTFNNNIIPAHFDSINGHSELVIEKVSKEDSGTYVCTAENSVGFVKAIGFVYVKEPPVFKGDYPSNWIEPLGGNAILNCEVKGDPAPT-IQWSRKGADIEISHRIRQLGNGSLAIYGTVNEDAGDYTCVAAN---------EAGMVERSMSLTLQ---SSPIITLEPVETVVDAGGRVILDC----QAAGEPQPTITWSRQGQPISWDNRLSMLPNSSLYIAAARKEDTSEYECVARNLMGSVLVRVPVIVQVHGGFSL 4533 HSP 12 Score: 67.0106 bits (162), Expect = 1.535e-9 Identity = 93/431 (21.58%), Postives = 171/431 (39.68%), Query Frame = 3 Query: 699 LENRGFVMCTAINDAGVLTKNTSLLNIKYKPKIKPFVPNTVNAMINQTIDLSCEVYANPAATIQWV-IMQGLQIIDSSKF--IAKIRPDMDGPLICEAKNYL-------GSTKETVQLNVLRDPLIHIDSNYRVPKNSNY------SINCRVTSNPPPEFIKWYKLSNMTDSSAVLISDDAKLNFILIDRSSTGMYACVTQNIQISTTGKRKPANSEKTMFLTVTYKPKEPQILGNKIISIMKGEKFIIKCSTDRKSPGEPFPTLKWI--DVETK-----DIVSDMETFQVINSESRHNGKYKCLAENEIGKSFSRETALVTVNEAPSIITQHKNRKVFLSYSDLPQSISFTCEFRGQPLYEARWRYGNEKIPPSSQDFKIEDHRNISNERISQIFTKLTIDLYSRTFSQQTSLRSSPNGRYNCEADNRHG 1922 L + GF C A++ AG + + ++ P I PN V + L+C V + + W + +++ DS++ +A + ++ I +A Y GS +V L V P + + +PKN ++ SI C T P P+ + + S ++ + L G YAC+ N ++T L PK ++ + + G+ +++C K+ G P P +KW D+E + I + ++ ++ G Y C+A NE G++ R T + V P I + + V ++ +++ C +G P + +WR + +P S+ F + IS R +F ++L +S G Y CEA+N+ G Sbjct: 491 LSDEGFYDCIAVSSAGT-GRAQTFFDVSEPPPIIQL-PNNVTVTPGERAVLACLVISAVDYNLTWQRSGRDIRLADSARIRTLANLSLELRSVKIGDAGEYRCVVSSEGGSAAASVFLTVQEKPKVTV-----MPKNQSFTGGSEISIMCSATGYPKPKIVWTMNEMFIMGSHRYRMTSEGTLFIKNAVPKDAGTYACLASNAA---------GTDKQTSTLRYIEAPK--LVVEQSELLVALGDTTVMEC----KTSGIPPPQVKWFKGDLELRPSTFLSIDPLVGLLKIQETQDLDAGDYTCVAINEAGRATGRLT--LDVGSPPVFIQEPSDVAV-----EIGSNVTLPCYVQGYPEPKIKWRR-LDNMPVFSRPFSVS---FISQLRTGALFI--------------SNLWASDKGTYICEAENQFG 874 HSP 13 Score: 55.8398 bits (133), Expect = 3.841e-6 Identity = 84/365 (23.01%), Postives = 143/365 (39.18%), Query Frame = 3 Query: 702 ENRGFVMCTAINDAGVLTKNTSLLNIKYKPKIKPF-VPNTVNAMINQTIDLSCEVYANPAATIQW-------VIMQGLQIIDSSKF--IAKIRPDMDGPLICEAKNYLGSTKETVQLNVLRDP-LIHID--SNYRVPKNSNYSINCRVTSNPPPEFIKWYKLSNMTDSS--AVLISDDAKLNFILIDRSSTGMYACVTQNIQISTTGKRKPANSEKTMFLTVTYKPKEPQILGNKIISIMKGEKFIIKCSTDRKSPGEPFPTLKW-----IDVETKDIVSDMETFQVINSESRH---NGKYKCLAENEIGKSFSRETALVTVNEAPSIITQHKNRKVFLSYSDLPQSISFTCEFRGQPLYEARWR 1727 E+ G C A N+AG ++K+ +L + P I P V+ ++N ++LSC PA I W + + +Q ++ ++ + + G C A + G + + V P + +D ++ V +N ++ C+ + PPP I W K ++ ++S L D T Y CV NI TT + LTV P G + + + + ++C ++ G P P + W + E+ S +E ++ ES H G+Y C+A N G R + V+ PSI N V ++ + CE G P WR Sbjct: 3498 EDTGKYTCVATNEAGEVSKHF-VLKVLEPPHINGSEGPGEVSVIVNNPLELSCIASGIPAPKISWMKDGRPFLQTEQVQTLEGGAILRVSSAQVEDTGRYTCLASSPAGDDDKEYLVRVHVPPNIAGMDEAQDFTVLRNRQVTLECKSDAVPPP-VIMWLKNREQLQATPRVRILSGGRYLQINNADLGDTANYTCVASNIAGKTT---------REFNLTVNVPPSIGG--GPQSLVTLLNKSIALEC----RAEGVPAPRITWRKDGVVLAESHARYSILEN-GFLHIESAHVTDTGRYLCMATNVAGT--DRRRIDLQVHVPPSIAMGPTNVTVTVN-----VQTTLACEATGIPKPSVTWR 3837
BLAST of hemicentin-1 isoform X2 vs. UniProt/SwissProt
Match: sp|O55005|ROBO1_RAT (Roundabout homolog 1 OS=Rattus norvegicus OX=10116 GN=Robo1 PE=1 SV=1) HSP 1 Score: 102.449 bits (254), Expect = 1.684e-20 Identity = 146/617 (23.66%), Postives = 241/617 (39.06%), Query Frame = 3 Query: 849 LSCEVYANPAATIQWVIMQGLQIIDSSK---------------FIAKI------RPDMDGPLICEAKNYLG---STKETVQLNVLRDPLIHIDSNYRVPKNSNYSINCRVTSNPPPEFIKWYK-LSNMTDSSAVLISDDAKLNFILIDRSSTGMYACVTQNIQISTTGKRKPANSEKTMFLTVTYKPKEPQILGNKIISIMKGEKFIIKCSTDRKSPGEPFPTLKWI--DVE---TKDIVSDMETFQVINSESRHNGKYKCLAENEIGKSFSRETALVTVNEAPSIITQHKNRKVFLSYSDLPQSISFTCEFRGQPLYEARWRY-GNEKIPPSSQDFKIEDHRNISNERISQIFTKLTIDLYSRTFSQQTSLRSSPNGRYNCEADNRHGIASLDYFLXXXXXXXXXXNIRHRKIAASLNQNVVM-----IRCQAESISTMHIKWYKTNEHIVLPFQSKKYSIFEAEVTKYEPERDLFTPGLKVNELTIKDLENDDFSNYSCVASNDQG-------IKKVNFEVVFKSQ--------PDPPYDLRVTDFEWDSVTINWKPGFNGGLT-QNYEILVISENFGTQNVPFYSDKNENTLTITGLYPSTPYEIRIYAVNSIG 2543 L+C+ P TI+W +G + +++ K F +I RPD +G IC A+NYLG S ++++ +LRD S+ V + C+ P I W K S + D + KL +S G Y CV N+ G+R+ K +TV +P + N +++ +F KC ++ G+P PT W D E ++ + D T ++ + G Y C+AEN +GK + +A +TV E P + + +++ V L ++++F CE G P WR G++ + F + ++ S +SQ LT+ T+++ S G Y C+ N G +L + + R+ +NQ V + + C A I W K + +++ Q + E+ V L I+ + D Y+C AS G I+ F V + P P VTD ++VT+ W+P N G T +Y I S G+ + T I GL P+ Y + A N+ G Sbjct: 87 LNCKAEGRPTPTIEW--YKGGERVETDKDDPRSHRMLLPSGSLFFLRIVHGRKSRPD-EGVYICVARNYLGEAVSHNASLEVAILRDDFRQNPSDVMVAVGEPAVMECQPPRGHPEPTISWKKDGSPLDDKDERITIRGGKLMITYTRKSDAGKYVCVGTNM----VGERE----SKVADVTVLERPSFVKRPSNLAVTVDDSAEF--KC----EARGDPVPTFGWRKDDGELPKSRYEIRDDHTLKIRKVTAGDMGSYTCVAENMVGK--AEASATLTVQEPPHFVVKPRDQVVALG-----RTVTFQCEATGNPQPAIFWRREGSQNL-----LFSYQPPQSSSRFSVSQT-GDLTV----------TNVQRSDVGYYICQTLNVAGSIITKAYLEVTDVIADRPPPVIRQ--GPVNQTVAVDGTLTLSCVATGSPVPTILWRK--DGVLVSTQDSRIKQLESGV------------------LQIRYAKLGDTGRYTCTASTPSGEATWSAYIEVQEFGVPVQPPRPTDPNLIPSAPSKPEVTDVSKNTVTLLWQPNLNSGATPTSYIIEAFSHASGSSWQTVAENVKTETFAIKGLKPNAIYLFLVRAANAYG 641 HSP 2 Score: 73.559 bits (179), Expect = 1.147e-11 Identity = 102/468 (21.79%), Postives = 170/468 (36.32%), Query Frame = 3 Query: 987 NYLGSTKETVQLNVLRDPLIHIDSNYRVPKNSNYSINCRVTSNPPPEFIKWYKLSNMTDS------SAVLISDDAKLNFILI-----DRSSTGMYACVTQNIQISTTGKRKPANSEKTMFLTVTYKPKEPQILGNKIISIMKGEKFIIKCSTDRKSPGEPFPTLKW------IDVETKDIVSDMETFQVINSESRHNGKYKCLAENEIGKSFSRETALVTVNEAPSIITQHKNRKVFLSYSDLPQSISFTCEFRGQPLYEARWRYGNEKIPPSSQDFKIEDHRNISNERISQIFTKLTIDLYSRTFSQQTSLRSSPNGRYNCEADNRHGIASLDYFLXXXXXXXXXXNIRHRKIAASLNQNVVMIRCQAESISTMHIKWYKTNEHIVL-----PFQSKKYSIFEAEVTKYEPERDLFTPGLKVNELTIKDLENDDFSNYSCVASNDQG--IKKVNFEV--VFKSQPDP 2312 N LG T ++ ++ S+ V K ++NC+ P P I+WYK ++ S ++ L F+ I R G+Y CV +N S + L ++ ++ + GE +++C R G P PT+ W +D + + I + + GKY C+ N +G+ S+ A VTV E PS + + N V + S F CE RG P+ WR + ++P S ++I D + +++ + G Y C A+N G A L ++ PP R + +A V +C+A I W + +L P S ++S+ + +LT+ +++ D Y C N G I K EV V +P P Sbjct: 52 NSLGYTGSRLRQEDFPPRIVEHPSDLIVSKGEPATLNCKAEGRPTPT-IEWYKGGERVETDKDDPRSHRMLLPSGSLFFLRIVHGRKSRPDEGVYICVARNYLGEAVSHNA---SLEVAILRDDFRQNPSDVM------VAVGEPAVMECQPPR---GHPEPTISWKKDGSPLDDKDERITIRGGKLMITYTRKSDAGKYVCVGTNMVGERESK-VADVTVLERPSFVKRPSNLAVTVD-----DSAEFKCEARGDPVPTFGWRKDDGELPKSR--YEIRDDHTLKIRKVT----------------------AGDMGSYTCVAENMVGKAEASATLTVQEPPHFVVKPRDQVVALG---RTVTFQCEATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSVSQ------------------TGDLTVTNVQRSDVGYYICQTLNVAGSIITKAYLEVTDVIADRPPP 455
BLAST of hemicentin-1 isoform X2 vs. TrEMBL
Match: A0A1S3HD63 (hemicentin-1 isoform X2 OS=Lingula unguis OX=7574 GN=LOC106154221 PE=4 SV=1) HSP 1 Score: 233.032 bits (593), Expect = 1.089e-58 Identity = 249/970 (25.67%), Postives = 395/970 (40.72%), Query Frame = 3 Query: 81 YFKTFILITLFGNLMDRSYTLNFLITPNNATVNSKENLTLECVVD-----QQNIVYSWEYKPFHIKSNIMSKVLGFCYFEKPCVVPDSESQITISHES--RLTIHNISSDNSGYYVCRVTLLTTSEHIISLAVVTVKTPPKSISFHFNKSINVFQEQEFIAIQCSVSGGIPPPKISMYIVKDNAIKRLKIISSNFPNSTIAEVSAISL----WRPHYLENRGFVMCTAINDAGVLTKNTS--LLNIKYKPKIKPFVP-NTVNAMINQTIDLSCEVYANPAAT-IQWVIMQGLQIID--SSKFIAKIRPDMDGPLICEAKNYLGSTKETVQLNVLRDP---LIHIDSNYRVPKNSNYSIN--CRVTSNPPPEFIKWYKLSNMTDSSAVLISDDAKLNFILIDRSSTGMYACVTQNIQISTTGKRKPA--NSEKTMFLTVTYKPKEPQILGNKIISIMKGEKFIIKCSTDRKSPGEPFPTLKWIDVETKDIVSDMETFQVINSESRHNGKYKCLAENEIGKSFSRETALVTVNEAPSIITQHKNRKVF----LSYSDLPQSISFTCEFRGQPLYEARWRYGNEKIPPSSQDFKIEDHRNISNERISQIFTKLTIDLYSRTFSQQTSLRSSPNGRYNCEADNR----HGIASLDYFLXXXXXXXXXXNIRHRKIAASLNQNVVMIRCQAESISTMHIKWYKTNEHIVLPFQSKKYSIFEAEVTKYEPERDLFTPGLKVNELTIKDLENDDFSNYSCVASNDQGIKKVNFEVVFKSQPDPPYDLRVTDFEWDSVTINWKPGFNGGLTQNYEILVISENFGTQ--NVPFYSDKNENTLTITGLYPSTPYEIRIYAVNSIGRSLNSETVKCVTKRIRKFDKIQAKILSDQPKIAVIIQEPDVCANLEYTRDNGH---QWFSILHCIRFNASHINETVLLDIIRVASILDLQSGLIHLRLTFCLISRPSVCSPHRIL 2879 + I TLF + + T ++ P VN ++TL C ++ Q N+++S+ K N S P S + + E+ L I N+S ++G Y C+V + + A +TV P + N S +E + + CS GG PPP IS + +DN + SS+ S AE+ + WR +N C N A T T+ N+++ P + F P N + T ++C V ANP T ++W+I G+ I + S + + +R G C A+N +GS+ T+ L+V P +I+I R+ N + +N C V +NPP I W K + + LI F + R+ GMY C +N T KR P S K L V Y+P I N ++ G+ +KC+ K G P L W V + S E + + NG Y+C +N++G+ E + V VNE P+ + Q+ +F +S D+ I C RG+P W I + + F I I I +T L R + T ++ Y C N G L + + + K+A +NQ ++ CQ+++ + +W + + I + S E+ GL+ + LTI + D NYSC+A+N G VN ++ + QPD P +LRV + WDSV + W PGFNGG Q + ++V + + G + V F N ITGL+P T Y ++Y N++ S+ V T + A + + Q C +E + N +W C TV + I++ S + LR+ CL SRP VC ++ Sbjct: 21 WMYAAIFTTLFMCVHAQDTTASWKQMPTAQAVNKGGDVTLSCEINNPGQFQINVIWSFNGKSITFNRNPFS----------PSTSDPRRSIVGANVETDFNLRITNLSLVDNGVYSCQVQ----GTDLTADAKLTVVVVPGTAVITTNNS-GTSKEGDTVFFNCSSFGGNPPPTISWF--RDNEPIQP---SSDIQYSPAAELGGSTSSKLSWRLRRADNEKMFACRVSNQANPSTPRTANTAANVQFAPVVN-FGPYNPLILREGATEQVACTVEANPQVTSVEWLI-DGVSIGNTRSVRLLDPVRLTDRGQHTCIARNIIGSSNATLTLDVQYPPKIEIINIQEGNRLTVNESSRVNLTCSVRANPPATEIVWRKNGTLQVAQPALI-------FQTVTRNRAGMYRCTAKNTL--TLSKRSPEVQESSKPAELVVQYRPGRAVI--NAHPEVVIGDPINLKCTVGDK--GIPEAQLFWERVGSTTQYSPGEDLNIPRAALDDNGSYRCTPKNKLGRGPHGEIS-VGVNEIPTWLQQNS---IFPARSVSVGDV--GIRLACRARGKPAPNIEWLKNGVPIENNGELFTIRTEEKI----IDTYSYNVTGYLEFRGTQRLTGIQVDDTANYTCLGSNHLSESRGGGKLSSSVELLVRYAPMLDRTQDKVAVDMNQTASLV-CQSQAYPAVTFRWIRAGQPITA---DGRRSFSESSGA-----------GLQTSTLTITRVSQGDLGNYSCIATNPVGETTVNIDLTVRRQPDAPTNLRVRENTWDSVLLEWTPGFNGGYDQTF-VIVKTNSSGKEEIQVGFVMQYN-----ITGLFPDTSYTFQVYGKNALKAGDYSQGVPVRTAALYVPPASDATFNGETGTLQFKSQYDQYCIRVEIEKKNAEGVLEWQEATPCAP-------PTVGDNSIKIQ-----DSTVSSLRVALCLTSRPEVCGAFSVV 912
BLAST of hemicentin-1 isoform X2 vs. TrEMBL
Match: A0A1S3HD72 (hemicentin-1 isoform X1 OS=Lingula unguis OX=7574 GN=LOC106154221 PE=4 SV=1) HSP 1 Score: 233.032 bits (593), Expect = 1.116e-58 Identity = 249/970 (25.67%), Postives = 395/970 (40.72%), Query Frame = 3 Query: 81 YFKTFILITLFGNLMDRSYTLNFLITPNNATVNSKENLTLECVVD-----QQNIVYSWEYKPFHIKSNIMSKVLGFCYFEKPCVVPDSESQITISHES--RLTIHNISSDNSGYYVCRVTLLTTSEHIISLAVVTVKTPPKSISFHFNKSINVFQEQEFIAIQCSVSGGIPPPKISMYIVKDNAIKRLKIISSNFPNSTIAEVSAISL----WRPHYLENRGFVMCTAINDAGVLTKNTS--LLNIKYKPKIKPFVP-NTVNAMINQTIDLSCEVYANPAAT-IQWVIMQGLQIID--SSKFIAKIRPDMDGPLICEAKNYLGSTKETVQLNVLRDP---LIHIDSNYRVPKNSNYSIN--CRVTSNPPPEFIKWYKLSNMTDSSAVLISDDAKLNFILIDRSSTGMYACVTQNIQISTTGKRKPA--NSEKTMFLTVTYKPKEPQILGNKIISIMKGEKFIIKCSTDRKSPGEPFPTLKWIDVETKDIVSDMETFQVINSESRHNGKYKCLAENEIGKSFSRETALVTVNEAPSIITQHKNRKVF----LSYSDLPQSISFTCEFRGQPLYEARWRYGNEKIPPSSQDFKIEDHRNISNERISQIFTKLTIDLYSRTFSQQTSLRSSPNGRYNCEADNR----HGIASLDYFLXXXXXXXXXXNIRHRKIAASLNQNVVMIRCQAESISTMHIKWYKTNEHIVLPFQSKKYSIFEAEVTKYEPERDLFTPGLKVNELTIKDLENDDFSNYSCVASNDQGIKKVNFEVVFKSQPDPPYDLRVTDFEWDSVTINWKPGFNGGLTQNYEILVISENFGTQ--NVPFYSDKNENTLTITGLYPSTPYEIRIYAVNSIGRSLNSETVKCVTKRIRKFDKIQAKILSDQPKIAVIIQEPDVCANLEYTRDNGH---QWFSILHCIRFNASHINETVLLDIIRVASILDLQSGLIHLRLTFCLISRPSVCSPHRIL 2879 + I TLF + + T ++ P VN ++TL C ++ Q N+++S+ K N S P S + + E+ L I N+S ++G Y C+V + + A +TV P + N S +E + + CS GG PPP IS + +DN + SS+ S AE+ + WR +N C N A T T+ N+++ P + F P N + T ++C V ANP T ++W+I G+ I + S + + +R G C A+N +GS+ T+ L+V P +I+I R+ N + +N C V +NPP I W K + + LI F + R+ GMY C +N T KR P S K L V Y+P I N ++ G+ +KC+ K G P L W V + S E + + NG Y+C +N++G+ E + V VNE P+ + Q+ +F +S D+ I C RG+P W I + + F I I I +T L R + T ++ Y C N G L + + + K+A +NQ ++ CQ+++ + +W + + I + S E+ GL+ + LTI + D NYSC+A+N G VN ++ + QPD P +LRV + WDSV + W PGFNGG Q + ++V + + G + V F N ITGL+P T Y ++Y N++ S+ V T + A + + Q C +E + N +W C TV + I++ S + LR+ CL SRP VC ++ Sbjct: 21 WMYAAIFTTLFMCVHAQDTTASWKQMPTAQAVNKGGDVTLSCEINNPGQFQINVIWSFNGKSITFNRNPFS----------PSTSDPRRSIVGANVETDFNLRITNLSLVDNGVYSCQVQ----GTDLTADAKLTVVVVPGTAVITTNNS-GTSKEGDTVFFNCSSFGGNPPPTISWF--RDNEPIQP---SSDIQYSPAAELGGSTSSKLSWRLRRADNEKMFACRVSNQANPSTPRTANTAANVQFAPVVN-FGPYNPLILREGATEQVACTVEANPQVTSVEWLI-DGVSIGNTRSVRLLDPVRLTDRGQHTCIARNIIGSSNATLTLDVQYPPKIEIINIQEGNRLTVNESSRVNLTCSVRANPPATEIVWRKNGTLQVAQPALI-------FQTVTRNRAGMYRCTAKNTL--TLSKRSPEVQESSKPAELVVQYRPGRAVI--NAHPEVVIGDPINLKCTVGDK--GIPEAQLFWERVGSTTQYSPGEDLNIPRAALDDNGSYRCTPKNKLGRGPHGEIS-VGVNEIPTWLQQNS---IFPARSVSVGDV--GIRLACRARGKPAPNIEWLKNGVPIENNGELFTIRTEEKI----IDTYSYNVTGYLEFRGTQRLTGIQVDDTANYTCLGSNHLSESRGGGKLSSSVELLVRYAPMLDRTQDKVAVDMNQTASLV-CQSQAYPAVTFRWIRAGQPITA---DGRRSFSESSGA-----------GLQTSTLTITRVSQGDLGNYSCIATNPVGETTVNIDLTVRRQPDAPTNLRVRENTWDSVLLEWTPGFNGGYDQTF-VIVKTNSSGKEEIQVGFVMQYN-----ITGLFPDTSYTFQVYGKNALKAGDYSQGVPVRTAALYVPPASDATFNGETGTLQFKSQYDQYCIRVEIEKKNAEGVLEWQEATPCAP-------PTVGDNSIKIQ-----DSTVSSLRVALCLTSRPEVCGAFSVV 912
BLAST of hemicentin-1 isoform X2 vs. TrEMBL
Match: A0A087U7N6 (Hemicentin-2 (Fragment) OS=Stegodyphus mimosarum OX=407821 GN=X975_20479 PE=4 SV=1) HSP 1 Score: 209.534 bits (532), Expect = 2.919e-51 Identity = 212/839 (25.27%), Postives = 354/839 (42.19%), Query Frame = 3 Query: 471 TPPKSISFHFNKSINVFQEQEFIAIQCSVSGGIPPPKISMYIVKDNAIKRLKI---ISSNFPNSTIAEVSAISLWRPHYLENRGFVMCTAINDAGVLTKNTSL-----LNIKYKPKIKPFVPNTVNAMINQTIDLSCEVYANPAA-TIQWVIMQGLQIIDSSKFIAKIRPDMDGPLICEAKNYLG-STKETVQLNVLRDPLIHIDSNYRVPKNSNYSINCRVTSNPPPEFIKWYKLSNMTDSSAVLISDDAKLNFILIDRSSTGMYAC-VTQNIQISTTGKRKPANSEKTMFLTVTYKPKEPQILGNKIISIMKGEKFIIKCSTDRKSPGEPFPTLKWI-DVETKDIVSDMETFQVINSESRHNGKYKCLAENEIGKSFSRETALVTVNEAPSIITQHKNRKVFLSYSDLPQSISFTCEFRGQPLYEARWRYGNEKIPPSSQDFKIEDHRNISNERISQIFTKLTIDLYSRTFSQQTSLRSSPNGRYNCEADNRHGIASLDYFLXXXXXXXXXXNIRH--RKIAASLNQNVVMIRCQAESISTMHIKWYKTNEHIVLPFQSKKYSIFEAEVTKYEPERDLFTPGLKVNELTIKDLENDDFSNYSCVASNDQGI-KKVNFEVVFKSQPDPPYDLRVTDFEWDSVTINWKPGFNGGLTQNYEILVISENFGTQNVPFYSDKNENTLTITGLYPSTPYEIRIYAVNSIGRSLNSETVKCVTKRIRKFDKIQAKILSDQPKIAVIIQEPDVCANLEYTRDNGHQWF-----SILHCIRFNASHINETV-----LLDIIRVASILDL---QSGLIHLRLTFCLISRPSVCSPHRILENPKNENL 2903 TPPK I+ +E+E I++ CS GG P P I Y +D + + K+ S P S++ +V+ P ++ C N A L N L L + Y P+I N +N + N L C V A+P +++WV L + I + PD G C A N +G ST+ ++L++L P + + S V + C V+S PP I+W K D D ++ + +D G Y C + + S + + A T+ + + +KP +IL + ++I G F + C+ G P P +W + + ++ + +I++ H G+Y C N +G+ S L TV+E SI+ K + V D ++ S TC RG+P + RW ++I S F I + + + FT +I ++ ++ L GRY CE DN G ++ ++ + +RH ++A + + V+ +C+ ++ +W+ + +Y + +T D++ L+I+D++ +D+ Y+C ASN G KK +V K P+ P L + + D VT+ W+ GFNGG + N E LV N T S +++N ITGL +T Y ++ AVN G S SE + TK D P+ + +Y +D G+ F S+ + A I V ++ +IR + L G +R+ CL S S C + L NP E+L Sbjct: 114 TPPKPIA----------RERETISLTCSSEGGSPDPTIRWY--RDGVLLQGKVQKGGSRERPTSSVLDVT------PRIEDDDSVYRCVVWNRA--LADNVKLDTSVSLRVHYSPRITVGPSNPLNVLENTDAHLICNVIASPPVRSVRWVKNGNLLSNTFNHTIRSVTPDDSGIYSCIADNGIGDSTQANLELSILYGPHVKVISYQEVAAGDTLVVKCDVSSKPPSHMIQWLKEG---DPYFRQTGDTLQIEKVSVDDG--GRYICEAAASFRPSGSNVQSEATGNGTVTVRIKHKPGLAEILPVQPVAIA-GRPFTLSCTA--HPLGWPLPEYRWWKEGQQSQELTPKSNYTLISAHMSHEGRYFCQPSNALGRGGSASVYL-TVHEPASIVHPLKPQTVM---KDKEKNYSITCRARGKPKPKVRWLQNGQEISEDSGLFHITTTDTVED---NNAFTVQSILAFAGPSRRENGLTPGDRGRYTCEFDNGFGESARSEMMLRIEHSPV---VRHTYNRVAFDVGETAVL-QCKMQAYPNPQFEWFSRGRVL------DEYGNYGTNITDLG--EDIY-----AGVLSIRDMKEEDYGEYTCRASNQVGDDKKTIIRLVRKGPPERPTHLELIEVSSDKVTLRWQEGFNGGFS-NTEFLVTYLNTETGRQFNESCRSQNLCQITGLSANTEYHFKVLAVNPRGYSPYSEEMPVTTK--------------DMPR----------PSEAQYDKDTGYLTFHVELTSLKLLAKIEAKPIGSEVWILQTVIKVIRPIEKVQLSPPDEGFSDVRVKLCLESNDSWCGDAK-LANPLEEDL 874
BLAST of hemicentin-1 isoform X2 vs. TrEMBL
Match: A0A224Z096 (Hemicentin-2-like OS=Rhipicephalus zambeziensis OX=60191 PE=4 SV=1) HSP 1 Score: 208.764 bits (530), Expect = 5.433e-51 Identity = 224/955 (23.46%), Postives = 395/955 (41.36%), Query Frame = 3 Query: 84 FKTFILITLFGNLMDRSYTLNFLITPNNATVNSKENLTLEC----VVDQQNIVYSWEYKPFHIKSN--IMSKVLGFCYFEKPCVVPDSESQITISHESRLTIHNISSDNSGYYVCRVTLLTTSEHIISLAV-VTVKTPPKSISFHFNKSINVFQEQEFIAIQCSVSGGIPPPKISMYIVKDNAIKRL-KIISSNFPNSTIAEVSAISLWRPHYLENRGFVMCTAINDA---GVLTKNTSLLNIKYKPKIKPFVPNTVNAMINQTIDLSCEVYANPAA-TIQWVIMQGLQIIDSSKFIAKIRPDMDGPLICEAKN-YLGSTKETVQLNVLRDPLIHIDSNYRVPKNSNYSINCRVTSNPPPEFIKWYKLSNMTDSSAVLISDDAKLNFILIDRSSTGMYAC-VTQNIQISTTGKRKPANSEKTMFLTVTYKPKEPQILGNKIISIMKGEKFIIKCSTDRKSPGEPFPTLKWIDVETKDI-VSDMETFQVINSESRHNGKYKCLAENEIGKSFSRETALVTVNEAPSIITQHKNRKVFLSYSDLPQSISFTCEFRGQPLYEARWRYGNEKIPPSSQ-DFKIEDHRNISNERISQIFTKLTIDLYSRTFSQQTSLRSSPNGRYNCEADNRHGIASLDYFLXXXXXXXXXXNIRHRKIAASLN-QNVVMIRCQAESISTMHIKWYKTNEHIVLPFQSKKYSIFEAEVTKYEPERDLFTPGLKVNELTIKDLENDDFSNYSCVASNDQG-IKKVNFEVVFKSQPDPPYDLRVTDFEWDSVTINWKPGFNGGLTQNYEILVISENFGTQNVPFYSDKNENTLTITGLYPSTPYEIRIYAVNSIGRSLNSETVKCVTK-RIRKFDK-IQAKILSDQPKIAVIIQE--PDVCANLEYTRDNGHQWFSILHCIRFNASHINETVLLDIIRVASILDLQSGLIHLRLTFCLISRPSVCSPHRILE 2882 F + L T+ L+ + + + P V E+L L C + +N++Y W H K N I L Y E + L ++G+Y C++ + + + A VTV P S E E +A+ C+ GG P P + + + L + + + P + + ++ P ++ C N A G + + + + Y PKI N +N M+ L+C V ANP +++W+ L + I + P+ G C A N L ++ + L+VL P +++ + N +I C V SNP P I W K D L D +L+ + + G Y C T ++ S T ++ L V +KP E +I ++ G F++ C + PG P P +W + I + ++ S H G+Y C N +GK S + + VNEA +II + ++ D QS S TC RG+P + W + ++++ S + F+I+ NI + + + + LT Q +L G+Y C DN G A+ ++ P +RH + + ++ ++RCQ ++ +W + ++Y+ + VT + DL+T L++ D++ D+ +Y+C A N G +++ ++V KS PD P L + D VT+ W GFNGG N E +V N + S ++ N TITGL P + Y +++ AVN+ G S SE + TK ++ + + A+ + ++ +++ + A +E QW + + + I+ L++ A+++D +R+ CL S S C R+ E Sbjct: 10 FSRWHLCTVLAVLLAARSSRSTPLEPEGRDVVEGESLRLSCNFNPALASRNLLYFWFRTNRHGKENAAISGSALDPHY--------SVEYNPAEGRYALLISRAQYDKDNGHYECKLKESGSGADVHNAAYDVTVLIAPGEP--RITPSSPTALEGEPLALTCASEGGSPDPDVDWFRGDERLPSALTRGGARDRPTAAVLTLT------PAREDDGAEFRCRITNRAMPQGSAYEARTTIRVHYAPKITVGPYNPLNVMVGTDATLTCSVLANPPVRSVRWMKRGQLLSNTYNHTIPSVTPEDSGNYACVADNGILQPSQVELHLSVLYGPRVNVLPEQEAAQGENVAIKCNVASNPEPHSILWTK---QGDGQFALQGDTLRLDRVTAE--DAGTYICQATVIMRPSATAIHTEVVGNDSVVLHVRHKPGEAEITPQGPTAVA-GRPFVLTCGA--RPPGWPRPEYRWWREGQEHIDLGHRSNHSFLSVHSSHEGRYFCQPHNALGKG-SIASVYLAVNEAATIIVPLRP-QIIRKAGD--QSQSVTCRARGKPKPQVHWTHRDKELQMSPESGFEIKTIENIEDNEVFSVQSTLTF---------QRALTPEDRGKYACLFDNGFGGAAKSEMMLRIEHPP---QVRHTYNRVAFDPGDMAVLRCQMQAYPEPTFEWVYKGRIL------ERYANYATNVT--DDGDDLYT-----GALSVADVKESDYGDYTCRAWNQVGDVQRTILKLVKKSAPDQPGRLVAVSSDSDKVTLQWTEGFNGGFG-NTEFVVTYSNVASGQTKNESCRSHNPCTITGLEPKSEYVMKVVAVNARGFSSYSEEITVQTKVNLKDMPRPLSAQFDQETGRVYFTVEQNTERLLARVEGRARGQEQWVPLAE-VEVDRPQIS----LEVANAANLVD-------IRVLLCLQSNASWCGDERLAE 898
BLAST of hemicentin-1 isoform X2 vs. TrEMBL
Match: A0A267F8R8 (Uncharacterized protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig027676g1 PE=4 SV=1) HSP 1 Score: 208.764 bits (530), Expect = 5.641e-51 Identity = 210/903 (23.26%), Postives = 357/903 (39.53%), Query Frame = 3 Query: 189 NLTLECVVDQQNIVYSWEYKPFHIKSNIMSKVLGFCYFEKPCVVPDSE----SQITISHESRLTIHNISSDNSGYYVCRV--TLLTTSEHIISLAVVTVKTPPKSISFHFNKSINVFQEQEFIAIQC-SVSGGIPPPKISMY---IVKDNAIKRLKIISSNFPNSTIAEVSAISLWRPHYLENRGFVMCTA----INDAGVLTKNTSLLNIKYKPKIKPFVPNTVNAMINQTIDLSCEVYANPAATIQWVIMQGLQIIDSSKFIAKIRP---DMDGPLICEAKNYLGSTKETVQLNVLRDPLIHIDSNYRVPKNSNYSINCRVTSNPPPEFIKWYKLSNMTDSSAVLISDDAKLNFILID-RSSTGMYACVTQNIQISTTGKRKPANSEKTMFLTVTYKPKEPQILGNKIISIMKGEKFIIKCSTDRKSPGEPFPTLKWIDVETKDI-VSDMETFQVINSESRHNGKYKCLAENEIGKSFSRETALVTVNEAPSIITQHKNRKVFLSYSDLPQSISFTCEFRGQPLYEARWRYGNEKIPPSSQDFKIEDHRNISNERISQIFTKLT----------IDLYSRTFSQQTSLRSSPNGRYNCEADNRHGIASLDYFLXXXXXXXXXXNIRHRKIAASLNQNVVMIRCQAESISTMHIKWYKTNEHIVLPFQSKKYSIFEAEVTKYEPERDLFTPGLKVNELTIKDLEND-DFSNYSCVASNDQGIKKVNFEVVFKSQPDPPYDLRVTDFEWDSVTINWKPGFNGGLTQNYEILVISEN--FGTQ---NVPFYSDKNENTLTITGLYPSTPYEIRIYAVNSIGRSL------NSETVKCVTKRIRKFDKIQAKILSDQPKIAVII--QEPDVCANLEYTRDNGHQWFS-----ILHCIRFNASHIN 2753 NL L C V ++ W Y + VL C+++ +S + + + L++ ++ GYY C L E I + VVT P +S C S SG PPP+++ I K + + P + S++ ++ ++CTA +++A V LL +K+KP I + A+ ++ ++C PA +Q + G + +S+ + + P G L C A N LG+ +L+VL P + ++ V + ++ C V NPPP + W + +A+ S D L D R G++ C ++I +++G + + LTV Y+P PQ ++ GE + C + SPGEP P+L W+ +++ + + + + +G Y C A N++G S S +L+ V++APS+ + + + C R P RW ++PP ++FT+L + L+ R F Q++ LR + G Y C ADN G ++ ++ L + P I + AA + + CQ S S + W +T + L S + + EA P + + D + NY+C +N G + ++V S PDPP L WDSV + WKPGF+GG + ++ N G + + P D TI GLYP T Y++ A N +G S N+ V T +R Q + S P ++ +P CA +E + D G W + + C+ F A ++ Sbjct: 57 NLRLHCNVSEKPDYIFWYYS--TVPGGTDRAVLARCHWDSATCAVESGFKAWANLVVMGSGTLSLAGVARSQDGYYECEAFRDRLDAKEGIRVVVVVTASEP------SIVQSPTQLTSGNLATFTCNSGSGWNPPPRLTWLRNSIDKPAGDDLTALALYSPPAAKFGPASSVLRLTVGADDHEAVLICTAAQAELSNASVSAAQLKLL-VKHKPSIGSIA--DLTAIEGSSVPVACSAGGYPAPRLQLIGANGSVMQESASGMFTLYPVDRSQAGALACRAVNPLGTATAAFRLSVLYQPTVRTPASAVVDAGGSVTLPCSVDGNPPPAELVWR---HDATGAALPPSSDGALRLDGADPRRHAGVWHCEARSILTASSGPPTEYTASSAVVLTVRYRPGLPQA-SQPRSPLLAGESVNLTCQPSQVSPGEPAPSLAWVQIQSSPVHLPAGPSVRFSPVGLSDSGSYACRAVNDLGTSESAPVSLL-VHQAPSLTVESAPTGANAARVG-STNFRLVCRVRANPAPRLRWLLNGARMPP-------------------ELFTELAGLGDQSFEYQLTLHFRGF-QRSVLRLNDTGVYQCFADNELGNSTAEHRLEVLTQPSI---VNAFDKAAFVPGRRPALACQFISHSGFSVTW-RTPDGRTLTTGSAQ-PVEEAN----------GQPWWMTSPAPLTDGGSQPAIGNYTCQVNNSLGTVQRRLQLVAVSAPDPPERLSAAPLAWDSVRLFWKPGFDGGHPAKLRLRLVGWNASVGARMPTSPPLLVDAEVGEATIGGLYPDTAYDVVCVAENRLGESPAFGAADNNAAVVVTTGHLR---LPQVRDASWDPATGRLVFRGQPGYCARVEASSDAGATWRAPPNADAVGCLAFQADGLS 904
BLAST of hemicentin-1 isoform X2 vs. Ensembl Cavefish
Match: ENSAMXT00000001796.2 (pep primary_assembly:Astyanax_mexicanus-2.0:20:23710211:23902940:-1 gene:ENSAMXG00000001638.2 transcript:ENSAMXT00000001796.2 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 109.383 bits (272), Expect = 1.591e-23 Identity = 146/634 (23.03%), Postives = 245/634 (38.64%), Query Frame = 3 Query: 849 LSCEVYANPAATIQWVI-------------MQGLQIIDSSKFIAKI------RPDMDGPLICEAKNYLG---STKETVQLNVLRDPLIHIDSNYRVPKNSNYSINCRVTSNPPPEFIKWYK-LSNMTDSSAVLISDDAKLNFILIDRSSTGMYACVTQNIQISTTGKRKPANSEKTMFLTVTYKPKEPQILGNKIISIMKGEKFIIKCSTDRKSPGEPFPTLKWIDVETK------DIVSDMETFQVINSESRHNGKYKCLAENEIGKSFSRETALVTVNEAPSIITQHKNRKVFLSYSDLPQSISFTCEFRGQPLYEARW-RYGNEKIPPSSQDFKIEDHRNISNERISQIFTKLTIDLYSRTFSQQTSLRSSPNGRYNCEADNRHGIASLDYFLXXXXXXXXXXNIRHRKIAASLNQNV-----VMIRCQAESISTMHIKWYKTNEHIVLPFQSKKYSIFEAEVTKYEPERDLFTPGLKVNELTIKDLENDDFSNYSCVASNDQG-------IKKVNFEVVFKSQ--------PDPPYDLRVTDFEWDSVTINWKPGFNGGLTQNYEILVISENFGTQNVPFYSDKNENTLTITGLYPSTPYEIRIYAVNSIGRSLNSETVKCVTKRIRKFD 2600 L+C+ P+ T++W + + S F +I +PD DG +C A+NYLG S ++++ +LRD ++ V + + C+ P I W K +N+ D + KL +S G Y CV N+ G+R+ +E T+ ++ + ++ ++ E +C ++ G+PFPT++W + + +I+ D T + G Y CLAEN +GK + +A +TV+ P+ + +N+ V + ++++F CE G P W R G++ + F + + S +SQ LTI T ++ S G Y+C+A N G L + + R+ NQ V V++ C A T + W K + S ++ +T+ L L I+ + D Y+CVA++ G + F V + P P VTD SVT++WK NG +Y I S G+ V + + GL PS Y + A N+ G S S +T IR D Sbjct: 48 LNCKAEGRPSPTVEWYKDGERVETDRDNPRSHRMLLPSGSLFFLRIVHGRRSKPD-DGSYVCVARNYLGEAVSHNASLEVAILRDDFRQNPADVMVAEGEPAVLECQPPRGHPEPTISWRKDGTNINDRDERITIRSGKLMITNARKSDAGKYVCVGTNM----VGERESEIAELTVLERPSFTRRPSSVV------VLADESVEFRC----EARGDPFPTIRWRKEDGELPKGRYEILED-HTLSLQRVTPADVGSYSCLAENMVGK--AEASATLTVHVPPAFAVRPRNQVVGVG-----RTVTFQCEATGNPQPAIFWQREGSQNL-----LFSYQPPQPSSRFSVSQT-GDLTI----------TDVQRSDGGLYSCQALNIAGSVITKALLEVTDVVSDRPPPVIRQ--GPENQTVAVDGTVLLNCVATGTPTPTLLWRKDGMLV---------STHDSRITQ-----------LDSGALQIRYAKLVDTGVYTCVATSPSGEASWKAYLAVEEFGVAVQPGRPTDPNLIPSAPSKPEVTDVTRTSVTLSWKASPNGATPTSYVIEAFSHASGSSWVTLADHVKTESFILKGLKPSAVYLFLVRAANAYGLSDPSP----ITDAIRTQD 616 HSP 2 Score: 81.2629 bits (199), Expect = 6.096e-15 Identity = 105/450 (23.33%), Postives = 172/450 (38.22%), Query Frame = 3 Query: 1041 LIHIDSNYRVPKNSNYSINCRVTSNPPPEFIKWYKLSNMTDS------SAVLISDDAKLNFILI-----DRSSTGMYACVTQNIQISTTGKRKPANSEKTMFLTVTYKPKEPQILGNKIISIMKGEKFIIKCSTDRKSPGEPFPTLKW------IDVETKDIVSDMETFQVINSESRHNGKYKCLAENEIGKSFSRETALVTVNEAPSIITQHKNRKVFLSYSDLPQSISFTCEFRGQPLYEARWRYGNEKIPPSSQDFKIEDHRNISNERISQIFTKLTIDLYSRTFSQQTSLRSSPNGRYNCEADNRHGIASLDYFLXXXXXXXXXXNIRHRKIAASLNQNVVMIRCQAESISTMHIKWYKTNEHIVL-----PFQSKKYSIFEAEVTKYEPERDLFTPGLKVNELTIKDLENDDFSNYSCVASNDQG--IKKVNFEV--VFKSQPDP 2312 ++ S+ V K ++NC+ P P ++WYK ++ S ++ L F+ I + G Y CV +N S + L ++ ++ + +GE +++C R G P PT+ W I+ + I + N+ GKY C+ N +G+ S E A +TV E PS T+ + V L+ +S+ F CE RG P RWR + ++P + +EDH +S +R++ D+ G Y+C A+N G A L + PP R++ + V +C+A I W + +L P S ++S+ + +LTI D++ D YSC A N G I K EV V +P P Sbjct: 31 IVEHPSDLIVSKGEPATLNCKAEGRPSPT-VEWYKDGERVETDRDNPRSHRMLLPSGSLFFLRIVHGRRSKPDDGSYVCVARNYLGEAVSHNA---SLEVAILRDDFRQNPADVM------VAEGEPAVLECQPPR---GHPEPTISWRKDGTNINDRDERITIRSGKLMITNARKSDAGKYVCVGTNMVGERES-EIAELTVLERPSF-TRRPSSVVVLA----DESVEFRCEARGDPFPTIRWRKEDGELPKGRYEI-LEDH-TLSLQRVT------PADV----------------GSYSCLAENMVGKAEASATLTVHVPPAFAVRPRNQVVGVG---RTVTFQCEATGNPQPAIFWQREGSQNLLFSYQPPQPSSRFSVSQ------------------TGDLTITDVQRSDGGLYSCQALNIAGSVITKALLEVTDVVSDRPPP 416 HSP 3 Score: 65.4698 bits (158), Expect = 4.145e-10 Identity = 97/429 (22.61%), Postives = 157/429 (36.60%), Query Frame = 3 Query: 360 RLTIHNISSDNSGYYVC--RVTLLTTSEHIISLAVVTVKTPPKSISFHFNKSINVFQEQEFIAIQCSVSGGIPPPKISMYIVKDNAIKRLKIISSNFPNSTIAEVSAISLWRPHYLENRGFVMCTAINDAGVLTKNTSLLNIKYKPKIKPFVPNTVNAMINQTIDLSCEVYANPAATIQWVIMQG------LQII-DSSKFIAKIRPDMDGPLICEAKNYLGSTKETVQLNVLRDPLIHI-DSNYRVPKNSNYSINCRVTSNPPPEFIKWYKLSNMT---------DSSAVLISDDAKLNFILIDRSSTGMYACVTQNIQISTTGKRKPANSEKTMFLTVTYKPKEPQILGNKIISIMKGEKFIIKCSTDRKSPGEPFPTLKW----IDVETKD---IVSDMETFQVINSESRHNGKYKCLAENEIGKS 1568 R+ S + G YVC R L H SL V ++ F N + + E E ++C G P P IS N R + I+ I + G +C N G + L + +P P++V + +++++ CE +P TI+W G +I+ D + + ++ P G C A+N +G + + L V P + N V + C T NP P I W + + SS +S L + RS G+Y+C NI S K A E T ++ P Q N+ +++ ++ C + G P PTL W + V T D D Q+ ++ G Y C+A + G++ Sbjct: 92 RIVHGRRSKPDDGSYVCVARNYLGEAVSHNASLEVAILRD-----DFRQNPADVMVAEGEPAVLECQPPRGHPEPTISWRKDGTNINDRDERITIRSGKLMITNARK---------SDAGKYVCVGTNMVGERESEIAELTVLERPSFT-RRPSSVVVLADESVEFRCEARGDPFPTIRWRKEDGELPKGRYEILEDHTLSLQRVTPADVGSYSCLAENMVGKAEASATLTVHVPPAFAVRPRNQVVGVGRTVTFQCEATGNPQPA-IFWQREGSQNLLFSYQPPQPSSRFSVSQTGDLTITDVQRSDGGLYSCQALNIAGSVITK---ALLEVTDVVSDRPPPVIRQGPENQTVAVDG--TVLLNCV----ATGTPTPTLLWRKDGMLVSTHDSRITQLDSGALQIRYAKLVDTGVYTCVATSPSGEA 495
BLAST of hemicentin-1 isoform X2 vs. Ensembl Cavefish
Match: robo1 (roundabout, axon guidance receptor, homolog 1 (Drosophila) [Source:ZFIN;Acc:ZDB-GENE-000209-3]) HSP 1 Score: 104.375 bits (259), Expect = 4.987e-22 Identity = 153/688 (22.24%), Postives = 260/688 (37.79%), Query Frame = 3 Query: 663 EVSAISLWRPHYLENRGFVMCTAINDA------GVLTKNTSLLNIKYKPKIKPFVPNTVNAMINQTIDLSCEVYANPAATIQWVI-------------MQGLQIIDSSKFIAKI------RPDMDGPLICEAKNYLG---STKETVQLNVLRDPLIHIDSNYRVPKNSNYSINCRVTSNPPPEFIKWYKLS-NMTDSSAVLISDDAKLNFILIDRSSTGMYACVTQNIQISTTGKRKPANSEKTMFLTVTY--KPKEPQILGNKIISIMKGEKFIIKCSTDRKSPGEPFPTLKWIDVETKDI------VSDMETFQVINSESRHNGKYKCLAENEIGKSFSRETALVTVNEAPSIITQHKNRKVFLSYSDLPQSISFTCEFRGQPLYEARW-RYGNEKIPPSSQDFKIEDHRNISNERISQIFTKLTIDLYSRTFSQQTSLRSSPNGRYNCEADNRHGIASLDYFLXXXXXXXXXXNIRHRKIAASLNQNV-----VMIRCQAESISTMHIKWYKTNEHIVLPFQSKKYSIFEAEVTKYEPERDLFTPGLKVNELTIKDLENDDFSNYSCVASNDQG-------IKKVNFEVVFKSQ--------PDPPYDLRVTDFEWDSVTINWKPGFNGGLT-QNYEILVISENFGTQNVPFYSDKNENTLTITGLYPSTPYEIRIYAVNSIGRS 2549 + S++S+ R + E F++ T + L T L Y P+I P+ + + L+C+ P T++W + + S F +I +PD +G +C A+NYLG S ++++ +LRD S+ V + C+ P I W K N+ D + KL +S G Y CV N+ G+R+ +E T+ ++ +P +L ++ + +C ++ G+P PT++W E ++ + D T ++ S G Y CLAEN +GK+ + TA +TV+ P + +N+ V + ++++F CE G P W R G++ + SSQ + ++S LTI T + G Y+C+A N G L + + R+ NQ V V++ CQA T I W K + +++ + + L L I+ + D Y+C+AS G ++ F V + P P VTD +V++ WKP N G T +Y I S G+ + + GL PS Y + + N+ G S Sbjct: 18 DASSVSIMRIAWSEATAFIIITLLRLGQSEVVESSLVPGTRLRLEDYPPRIVEH-PSDLIVSKGEPATLNCKAEGRPTPTVEWYKDGERVETDRDNSRSHRMLLPSGSLFFLRIVHGRRSKPD-EGSYVCVARNYLGEAVSHNASLEVAILRDEFRQNPSDVMVAAGEPAVMECQPPRGHPEPTISWKKDGVNVDDRDERITIRGGKLMITNTRKSDAGKYVCVGTNMM----GERESEIAELTVLERPSFLRRPSSQSVLVDQSVEF--------RC----EAQGDPVPTVRWRK-EDGELPKGRFEIRDDHTLKLKRLSSADAGSYTCLAENMMGKTEA--TATLTVHVPPVFAVRPRNQVVGVG-----RTVTFQCEATGSPQPAIFWQREGSQNLLFSSQPPQPSSRFSVSQ------TGDLTI----------TGIERGDAGYYSCQALNIAGSVITKALLEVTDIISDRPPPVVRQ--GPTNQTVAVDGTVVLGCQATGTPTPTILWRK--DGVLVSTHDSRLKL------------------LDTGALQIRYAKLGDTGMYTCIASTPSGEASWKAYLEVQEFGVAVQPGRPTDPNLIPSAPSKPEVTDVTRSTVSLTWKPDLNSGATPTSYIIEAFSHASGSSWQTLAEHVRTESYVLKGLKPSAVYLFLVRSANAYGLS 641 HSP 2 Score: 69.3218 bits (168), Expect = 2.844e-11 Identity = 98/434 (22.58%), Postives = 160/434 (36.87%), Query Frame = 3 Query: 360 RLTIHNISSDNSGYYVC--RVTLLTTSEHIISLAVVTVKTPPKSISFHFNKSINVFQEQEFIAIQCSVSGGIPPPKISMY---IVKDNAIKRLKIISSNFPNSTIAEVSAISLWRPHYLENRGFVMCTAINDAGVLTKNTSLLNIKYKPKIKPFV--PNTVNAMINQTIDLSCEVYANPAATIQWVIMQG------LQIIDSSKFIAKIRPDMD-GPLICEAKNYLGSTKETVQLNVLRDPLIHI-DSNYRVPKNSNYSINCRVTSNPPPEFIKWYKLSNMT---------DSSAVLISDDAKLNFILIDRSSTGMYACVTQNIQISTTGKRKPANSEKTMFLTVTYKPKEPQILGNKIISIMKGEKFIIKCSTDRKSPGEPFPTLKW----IDVETKDI---VSDMETFQVINSESRHNGKYKCLAENEIGKS 1568 R+ S + G YVC R L H SL V ++ F N S + E ++C G P P IS + D+ +R+ I + + A G +C N G + L + +P F+ P++ + +++Q+++ CE +P T++W G +I D K D G C A+N +G T+ T L V P+ + N V + C T +P P I W + + SS +S L I+R G Y+C NI S K A E T ++ P Q N+ +++ ++ C ++ G P PT+ W + V T D + D Q+ ++ G Y C+A G++ Sbjct: 129 RIVHGRRSKPDEGSYVCVARNYLGEAVSHNASLEVAILRD-----EFRQNPSDVMVAAGEPAVMECQPPRGHPEPTISWKKDGVNVDDRDERITIRGGKLMITNTRKSDA------------GKYVCVGTNMMGERESEIAELTVLERPS---FLRRPSSQSVLVDQSVEFRCEAQGDPVPTVRWRKEDGELPKGRFEIRDDHTLKLKRLSSADAGSYTCLAENMMGKTEATATLTVHVPPVFAVRPRNQVVGVGRTVTFQCEATGSPQPA-IFWQREGSQNLLFSSQPPQPSSRFSVSQTGDLTITGIERGDAGYYSCQALNIAGSVITK---ALLEVTDIISDRPPPVVRQGPTNQTVAVDG--TVVLGC----QATGTPTPTILWRKDGVLVSTHDSRLKLLDTGALQIRYAKLGDTGMYTCIASTPSGEA 532
BLAST of hemicentin-1 isoform X2 vs. Ensembl Cavefish
Match: robo2 (roundabout, axon guidance receptor, homolog 2 (Drosophila) [Source:ZFIN;Acc:ZDB-GENE-001019-1]) HSP 1 Score: 103.99 bits (258), Expect = 6.765e-22 Identity = 141/618 (22.82%), Postives = 237/618 (38.35%), Query Frame = 3 Query: 849 LSCEVYANPAATIQWVI-------------MQGLQIIDSSKFIAKI------RPDMDGPLICEAKNYLG---STKETVQLNVLRDPLIHIDSNYRVPKNSNYSINCRVTSNPPPEFIKWYKLSNMTDSSAVLIS-DDAKLNFILIDRSSTGMYACVTQNIQISTTGKRKPANSEKTMFLTVTYKPKEPQILGNKIISI-MKGEKFIIKCSTDRKSPGEPFPTLKW----IDVETK--DIVSDMETF--QVINSESRHNGKYKCLAENEIGKSFSRETALVTVNEAPSIITQHKNRKVFLSYSDLPQSISFTCEFRGQPLYEARWRYGNEKIPPSSQDFKIEDHRNISNERIS-QIFTKLTIDLYSRTFSQQTSLRSSPNGRYNCEADNRHG--IASLDYFLXXXXXXXXXXNIRHRKIAASLN-QNVVMIRCQAESISTMHIKWYKTNEHIVLPFQSKKYSIFEAEVTKYEPERDLFTPGLKVNELTIKDLENDDFSNYSCVASNDQG---------IKKVNFEVVFKSQ-----PDPPYDLRVTDFEWDSVTINWKPGFNGG-LTQNYEILVISENFGTQNVPFYSDKNENTLTITGLYPSTPYEIRIYAVNSIGRS 2549 L+C+ P T++W + + S F +I +PD +G +C A+NYLG S ++++ +LRD ++ V + C P I W K D I KL +S GMY CV N+ G+R ++ T+F + P L I + ++ E +C G+P P+++W +DV DI D + + ++ + + G + C+AEN +GK +A +TV P + + +++ V ++ +F CE +G P W+ SQ+ + N R S LTI T ++ + G Y C+A G +A + IR +L V +++CQA I W K + + L + + S+ L + L IK++ D Y+CVA++ G +K+ V K++ P PP +VTD +SV+++W+PG G +T +Y I S++ TI L P+T Y + AVN+ G S Sbjct: 50 LNCKAEGRPTPTVEWYKDGERVETDKDDSRSHRMLLPSGSLFFLRIVHGRRSKPD-EGAYVCVARNYLGEAVSRNASLEVALLRDDFRQNPTDVVVAAGEPAILECVPPRGHPEPTIFWKKDKVRIDEKEDRIKIRGGKLMISNTRKSDAGMYVCVGTNM----VGERDSETAQVTVF-------ERPTFLRRPINQVVLEDEAVEFRCQVQ----GDPQPSVRWRKDDVDVARGRYDIRYDKDDYVLRIKKASAGDEGTFTCVAENRVGKL--EASATLTVRAPPQFVIRPRDQIVAQG-----RTATFPCETKGNPQPAVFWQKEG------SQNLLFPNQPQQPNSRFSVSPSGDLTI----------TGVQRADAGYYICQALTVAGSILAKAQLEVTDVLTDRPPPIIRQGPANQTLGVDGVALLKCQASGEPVPTISWRK--DGVSLLGKDPRMSL------------------LDLGSLQIKNIRLSDSGIYTCVAASSSGETSWSAFLEVKESAGVVTIKNRDESELPGPPSKPQVTDVTKNSVSLSWQPGLTGASVTTSYVIEAFSQSVSNSWQTVADHVKTTQYTIKSLRPNTIYLFMVRAVNAQGLS 608 HSP 2 Score: 64.3142 bits (155), Expect = 9.428e-10 Identity = 103/464 (22.20%), Postives = 171/464 (36.85%), Query Frame = 3 Query: 360 RLTIHNISSDNSGYYVC--RVTLLTTSEHIISLAVVTVKTPPKSISFHFNKSINVFQEQEFIAIQCSVSGGIPPPKISMYIVK---DNAIKRLKIISSNFPNSTIAEVSAISLWRPHYLENRGFVMCTAINDAGVLTKNTSLLNIKYKPKIKPFVPNTVNAMI--NQTIDLSCEVYANPAATIQWV-----IMQGLQII--DSSKFIAKIR---PDMDGPLICEAKNYLGSTKETVQLNVLRDPLIHIDSNYR-VPKNSNYSINCRVTSNPPPEFIKWYKLSN---------MTDSSAVLISDDAKLNFILIDRSSTGMYACVTQNIQISTTGKRKPANSEKTMFLTVTYKPKEPQILGNKIISIMKGEKFIIKCSTDRKSPGEPFPTLKWIDVETKDIVS-----------DMETFQVINSESRHNGKYKCLAENEIGKSFSRETALVTVNEAPSIITQHKNR 1637 R+ S + G YVC R L SL V ++ F N + V E ++C G P P I K D R+KI S + A G +C N G T+ + + +P F+ +N ++ ++ ++ C+V +P +++W + +G I D ++ +I+ +G C A+N +G + + L V P I + V + + C NP P W K + +S +S L + R+ G Y C + S K A E T LT P Q N+ + + ++KC ++ GEP PT+ W KD VS D+ + Q+ N +G Y C+A + G+ + +A + V E+ ++T KNR Sbjct: 94 RIVHGRRSKPDEGAYVCVARNYLGEAVSRNASLEVALLRD-----DFRQNPTDVVVAAGEPAILECVPPRGHPEPTIFWKKDKVRIDEKEDRIKIRGGKLMISNTRKSDA------------GMYVCVGTNMVGERDSETAQVTVFERPT---FLRRPINQVVLEDEAVEFRCQVQGDPQPSVRWRKDDVDVARGRYDIRYDKDDYVLRIKKASAGDEGTFTCVAENRVGKLEASATLTVRAPPQFVIRPRDQIVAQGRTATFPCETKGNPQPAVF-WQKEGSQNLLFPNQPQQPNSRFSVSPSGDLTITGVQRADAGYYICQALTVAGSILAK---AQLEVTDVLTDRPPPIIRQGPANQTLGV--DGVALLKC----QASGEPVPTISW----RKDGVSLLGKDPRMSLLDLGSLQIKNIRLSDSGIYTCVAASSSGE--TSWSAFLEVKESAGVVT-IKNR 520
BLAST of hemicentin-1 isoform X2 vs. Ensembl Cavefish
Match: robo1 (roundabout, axon guidance receptor, homolog 1 (Drosophila) [Source:ZFIN;Acc:ZDB-GENE-000209-3]) HSP 1 Score: 103.605 bits (257), Expect = 9.593e-22 Identity = 149/652 (22.85%), Postives = 247/652 (37.88%), Query Frame = 3 Query: 747 VLTKNTSLLNIKYKPKIKPFVPNTVNAMINQTIDLSCEVYANPAATIQWVI-------------MQGLQIIDSSKFIAKI------RPDMDGPLICEAKNYLG---STKETVQLNVLRDPLIHIDSNYRVPKNSNYSINCRVTSNPPPEFIKWYKLS-NMTDSSAVLISDDAKLNFILIDRSSTGMYACVTQNIQISTTGKRKPANSEKTMFLTVTYKPKEPQILGNKIISIMKGEKFIIKCSTDRKSPGEPFPTLKWIDVETKDI------VSDMETFQVINSESRHNGKYKCLAENEIGKSFSRETALVTVNEAPSIITQHKNRKVFLSYSDLPQSISFTCEFRGQPLYEARW-RYGNEKIPPSSQDFKIEDHRNISNERISQIFTKLTIDLYSRTFSQQTSLRSSPNGRYNCEADNRHGIASLDYFLXXXXXXXXXXNIRHRKIAASLNQNV-----VMIRCQAESISTMHIKWYKTNEHIVLPFQSKKYSIFEAEVTKYEPERDLFTPGLKVNELTIKDLENDDFSNYSCVASNDQG-------IKKVNFEVVFKSQ--------PDPPYDLRVTDFEWDSVTINWKPGFNGGLT-QNYEILVISENFGTQNVPFYSDKNENTLTITGLYPSTPYEIRIYAVNSIGRS 2549 V T L Y P+I P+ + + L+C+ P T++W + + S F +I +PD +G +C A+NYLG S ++++ +LRD S+ V + C+ P I W K N+ D + KL +S G Y CV N+ G+R+ +E LTV +P + ++ + + + +F +C ++ G+P PT++W E ++ + D T ++ S G Y CLAEN +GK+ TA +TV+ P + +N+ V + ++++F CE G P W R G++ + SSQ + ++S LTI T + G Y+C+A N G L + + R+ NQ V V++ CQA T I W K + +++ + + L L I+ + D Y+C+AS G ++ F V + P P VTD +V++ WKP N G T +Y I S G+ + + GL PS Y + + N+ G S Sbjct: 17 VCPPGTRLRLEDYPPRIVEH-PSDLIVSKGEPATLNCKAEGRPTPTVEWYKDGERVETDRDNSRSHRMLLPSGSLFFLRIVHGRRSKPD-EGSYVCVARNYLGEAVSHNASLEVAILRDEFRQNPSDVMVAAGEPAVMECQPPRGHPEPTISWKKDGVNVDDRDERITIRGGKLMITNTRKSDAGKYVCVGTNMM----GERESEIAE----LTVLERPSFLRRPSSQSVLVDQSVEF--RC----EAQGDPVPTVRWRK-EDGELPKGRFEIRDDHTLKLKRLSSADAGSYTCLAENMMGKT--EATATLTVHVPPVFAVRPRNQVVGVG-----RTVTFQCEATGSPQPAIFWQREGSQNLLFSSQPPQPSSRFSVSQT------GDLTI----------TGIERGDAGYYSCQALNIAGSVITKALLEVTDIISDRPPPVVRQ--GPTNQTVAVDGTVVLGCQATGTPTPTILWRK--DGVLVSTHDSRLKL------------------LDTGALQIRYAKLGDTGMYTCIASTPSGEASWKAYLEVQEFGVAVQPGRPTDPNLIPSAPSKPEVTDVTRSTVSLTWKPDLNSGATPTSYIIEAFSHASGSSWQTLAEHVRTESYVLKGLKPSAVYLFLVRSANAYGLS 606 HSP 2 Score: 70.4774 bits (171), Expect = 1.267e-11 Identity = 98/434 (22.58%), Postives = 160/434 (36.87%), Query Frame = 3 Query: 360 RLTIHNISSDNSGYYVC--RVTLLTTSEHIISLAVVTVKTPPKSISFHFNKSINVFQEQEFIAIQCSVSGGIPPPKISMY---IVKDNAIKRLKIISSNFPNSTIAEVSAISLWRPHYLENRGFVMCTAINDAGVLTKNTSLLNIKYKPKIKPFV--PNTVNAMINQTIDLSCEVYANPAATIQWVIMQG------LQIIDSSKFIAKIRPDMD-GPLICEAKNYLGSTKETVQLNVLRDPLIHI-DSNYRVPKNSNYSINCRVTSNPPPEFIKWYKLSNMT---------DSSAVLISDDAKLNFILIDRSSTGMYACVTQNIQISTTGKRKPANSEKTMFLTVTYKPKEPQILGNKIISIMKGEKFIIKCSTDRKSPGEPFPTLKW----IDVETKDI---VSDMETFQVINSESRHNGKYKCLAENEIGKS 1568 R+ S + G YVC R L H SL V ++ F N S + E ++C G P P IS + D+ +R+ I + + A G +C N G + L + +P F+ P++ + +++Q+++ CE +P T++W G +I D K D G C A+N +G T+ T L V P+ + N V + C T +P P I W + + SS +S L I+R G Y+C NI S K A E T ++ P Q N+ +++ ++ C ++ G P PT+ W + V T D + D Q+ ++ G Y C+A G++ Sbjct: 94 RIVHGRRSKPDEGSYVCVARNYLGEAVSHNASLEVAILRD-----EFRQNPSDVMVAAGEPAVMECQPPRGHPEPTISWKKDGVNVDDRDERITIRGGKLMITNTRKSDA------------GKYVCVGTNMMGERESEIAELTVLERPS---FLRRPSSQSVLVDQSVEFRCEAQGDPVPTVRWRKEDGELPKGRFEIRDDHTLKLKRLSSADAGSYTCLAENMMGKTEATATLTVHVPPVFAVRPRNQVVGVGRTVTFQCEATGSPQPA-IFWQREGSQNLLFSSQPPQPSSRFSVSQTGDLTITGIERGDAGYYSCQALNIAGSVITK---ALLEVTDIISDRPPPVVRQGPTNQTVAV--DGTVVLGC----QATGTPTPTILWRKDGVLVSTHDSRLKLLDTGALQIRYAKLGDTGMYTCIASTPSGEA 497
BLAST of hemicentin-1 isoform X2 vs. Ensembl Cavefish
Match: robo1 (roundabout, axon guidance receptor, homolog 1 (Drosophila) [Source:ZFIN;Acc:ZDB-GENE-000209-3]) HSP 1 Score: 101.679 bits (252), Expect = 3.850e-21 Identity = 147/651 (22.58%), Postives = 246/651 (37.79%), Query Frame = 3 Query: 756 KNTSLLNIKYKPKIKPFVPNTVNAMINQTIDLSCEVYANPAATIQWVI-------------MQGLQIIDSSKFIAKI------RPDMDGPLICEAKNYLG---STKETVQLNVLRDPLIHIDSNYRVPKNSNYSINCRVTSNPPPEFIKWYKLS-NMTDSSAVLISDDAKLNFILIDRSSTGMYACVTQNIQISTTGKRKPANSEKTMFLTVTY--KPKEPQILGNKIISIMKGEKFIIKCSTDRKSPGEPFPTLKWIDVETKDI------VSDMETFQVINSESRHNGKYKCLAENEIGKSFSRETALVTVNEAPSIITQHKNRKVFLSYSDLPQSISFTCEFRGQPLYEARW-RYGNEKIPPSSQDFKIEDHRNISNERISQIFTKLTIDLYSRTFSQQTSLRSSPNGRYNCEADNRHGIASLDYFLXXXXXXXXXXNIRHRKIAASLNQNV-----VMIRCQAESISTMHIKWYKTNEHIVLPFQSKKYSIFEAEVTKYEPERDLFTPGLKVNELTIKDLENDDFSNYSCVASNDQG-------IKKVNFEVVFKSQ--------PDPPYDLRVTDFEWDSVTINWKPGFNGGLT-QNYEILVISENFGTQNVPFYSDKNENTLTITGLYPSTPYEIRIYAVNSIGRS 2549 K T L Y P+I P+ + + L+C+ P T++W + + S F +I +PD +G +C A+NYLG S ++++ +LRD S+ V + C+ P I W K N+ D + KL +S G Y CV N+ G+R+ +E T+ ++ +P +L ++ + +C ++ G+P PT++W E ++ + D T ++ S G Y CLAEN +GK+ + TA +TV+ P + +N+ V + ++++F CE G P W R G++ + SSQ + ++S LTI T + G Y+C+A N G L + + R+ NQ V V++ CQA T I W K + +++ + + L L I+ + D Y+C+AS G ++ F V + P P VTD +V++ WKP N G T +Y I S G+ + + GL PS Y + + N+ G S Sbjct: 34 KGTRLRLEDYPPRIVEH-PSDLIVSKGEPATLNCKAEGRPTPTVEWYKDGERVETDRDNSRSHRMLLPSGSLFFLRIVHGRRSKPD-EGSYVCVARNYLGEAVSHNASLEVAILRDEFRQNPSDVMVAAGEPAVMECQPPRGHPEPTISWKKDGVNVDDRDERITIRGGKLMITNTRKSDAGKYVCVGTNMM----GERESEIAELTVLERPSFLRRPSSQSVLVDQSVEF--------RC----EAQGDPVPTVRWRK-EDGELPKGRFEIRDDHTLKLKRLSSADAGSYTCLAENMMGKTEA--TATLTVHVPPVFAVRPRNQVVGVG-----RTVTFQCEATGSPQPAIFWQREGSQNLLFSSQPPQPSSRFSVSQ------TGDLTI----------TGIERGDAGYYSCQALNIAGSVITKALLEVTDIISDRPPPVVRQ--GPTNQTVAVDGTVVLGCQATGTPTPTILWRK--DGVLVSTHDSRLKL------------------LDTGALQIRYAKLGDTGMYTCIASTPSGEASWKAYLEVQEFGVAVQPGRPTDPNLIPSAPSKPEVTDVTRSTVSLTWKPDLNSGATPTSYIIEAFSHASGSSWQTLAEHVRTESYVLKGLKPSAVYLFLVRSANAYGLS 620 HSP 2 Score: 69.3218 bits (168), Expect = 2.813e-11 Identity = 98/434 (22.58%), Postives = 160/434 (36.87%), Query Frame = 3 Query: 360 RLTIHNISSDNSGYYVC--RVTLLTTSEHIISLAVVTVKTPPKSISFHFNKSINVFQEQEFIAIQCSVSGGIPPPKISMY---IVKDNAIKRLKIISSNFPNSTIAEVSAISLWRPHYLENRGFVMCTAINDAGVLTKNTSLLNIKYKPKIKPFV--PNTVNAMINQTIDLSCEVYANPAATIQWVIMQG------LQIIDSSKFIAKIRPDMD-GPLICEAKNYLGSTKETVQLNVLRDPLIHI-DSNYRVPKNSNYSINCRVTSNPPPEFIKWYKLSNMT---------DSSAVLISDDAKLNFILIDRSSTGMYACVTQNIQISTTGKRKPANSEKTMFLTVTYKPKEPQILGNKIISIMKGEKFIIKCSTDRKSPGEPFPTLKW----IDVETKDI---VSDMETFQVINSESRHNGKYKCLAENEIGKS 1568 R+ S + G YVC R L H SL V ++ F N S + E ++C G P P IS + D+ +R+ I + + A G +C N G + L + +P F+ P++ + +++Q+++ CE +P T++W G +I D K D G C A+N +G T+ T L V P+ + N V + C T +P P I W + + SS +S L I+R G Y+C NI S K A E T ++ P Q N+ +++ ++ C ++ G P PT+ W + V T D + D Q+ ++ G Y C+A G++ Sbjct: 108 RIVHGRRSKPDEGSYVCVARNYLGEAVSHNASLEVAILRD-----EFRQNPSDVMVAAGEPAVMECQPPRGHPEPTISWKKDGVNVDDRDERITIRGGKLMITNTRKSDA------------GKYVCVGTNMMGERESEIAELTVLERPS---FLRRPSSQSVLVDQSVEFRCEAQGDPVPTVRWRKEDGELPKGRFEIRDDHTLKLKRLSSADAGSYTCLAENMMGKTEATATLTVHVPPVFAVRPRNQVVGVGRTVTFQCEATGSPQPA-IFWQREGSQNLLFSSQPPQPSSRFSVSQTGDLTITGIERGDAGYYSCQALNIAGSVITK---ALLEVTDIISDRPPPVVRQGPTNQTVAVDG--TVVLGC----QATGTPTPTILWRKDGVLVSTHDSRLKLLDTGALQIRYAKLGDTGMYTCIASTPSGEA 511
BLAST of hemicentin-1 isoform X2 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000010567.1 (pep scaffold:Pmarinus_7.0:GL479154:561817:685780:1 gene:ENSPMAG00000009565.1 transcript:ENSPMAT00000010567.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 90.8929 bits (224), Expect = 1.396e-18 Identity = 143/623 (22.95%), Postives = 233/623 (37.40%), Query Frame = 3 Query: 849 LSCEVYANPAATIQWVI-------------MQGLQIIDSSKFIAKI----RPDMD-GPLICEAKNYLGSTKETVQLNVLRDPLIHIDSNYR-------VPKNSNYSINCRVTSNPPPEFIKWYKLS-NMTDSSAVLISDDAKLNFILIDRSSTGMYACVTQNIQISTTGKRKPANSEKTMFLTVTYKPKEPQILGNKIISIMKGEKFIIKCSTDRKSPGEPFPTLKWIDVETKDI-------VSDMETFQVINSESRHNGKYKCLAENEIGKSFSRETALVTVNEAPSIITQHKNRKVFLSYSDLPQSISFTCEFRGQPLYEARWRYGNEKIPPSSQDFKIEDHRNISNERISQIFTK-LTIDLYSRTFSQQTSLRSSPNGRYNCEADNRHG--IASLDYFLXXXXXXXXXXNIRHRKIAASLN-QNVVMIRCQAESISTMHIKWYKTNEHIVLPFQSKKYSIFEAEVTKYEPERDLFTPGLKV-NELTIKDLENDDFSNYSCVASN--------------DQGIKKVNFEVVFKSQPDPPYDLRVTDFEWDSVTINWK-PGFNGGLTQNYEILVI---SENFGTQNVPFYSDKNENTLTITGLYPSTPYEIRIYAVNSIGRS 2549 L+C+ PA T++W + + S F +I R D G +C A+NYLG E V N + + +I NYR V + CR P + W + +TD + KL ++ GMY CV N+ G+R +E +F T+ K ++ ++ +C G+P PT++W E D+ + D T +V G Y C+ EN +GK + +A + V+ P + + +++ V QS +F CE G P W+ SQ+ + + + R S T LTI T ++ S +G Y C+A + G +A + IR +L +V ++ CQA + T + W K K S+ A + GL+ L+IKD++ D Y+CVA + + G+ S PP RVTD ++VT++W+ P +G Y I+ S++ T + + T+ GL P+T Y + A N+ G S Sbjct: 49 LNCKAEGRPAPTVEWYKDGERVETDRDDPRSHRMLLPTGSLFFLRIVHGRRTKTDEGSYVCVARNYLG---EAVSRNASLE-VANIRRNYRSSPSAVKVAAREPAVMECRPPRGHPEPTVSWKRNGVALTDKDERVTIRGGKLMISNTQKADAGMYVCVGTNM----VGERDSEPAELAVFERPTFARKPMNLV------MLADSDAEFRCEVH----GDPPPTVRWRK-EDGDLPKGSRFEIQDDYTLRVERVGGTDEGTYTCVGENRVGK--AEASASLVVHAPPQFVVRPRDQIVAQG-----QSATFLCETTGNPPPAVFWQR------EGSQNLLFPNQPSQPSSRFSVSQTGHLTI----------TDVQRSDSGYYTCQALSVAGSILAKALLEVGDALADSPPPIIRQGPANQTLAVGSVALLACQAMGMPTPSVHWLK---------DGSKLSLGSARL------------GLQSGGTLSIKDVQLMDAGLYTCVAVSPSGETTWSAFMDVQENGVPSQPQPPEPSSLAAPPSKPRVTDVTKNTVTLSWQLPEPSGPSPILYYIIEAFRDSQSVSTSWQTVATHVTRDAFTLRGLRPNTIYLFIVRAANAHGLS 608 HSP 2 Score: 51.9878 bits (123), Expect = 1.104e-6 Identity = 61/314 (19.43%), Postives = 117/314 (37.26%), Query Frame = 3 Query: 705 NRGFVMCTAINDAGVLTKNTSLLNIKYKPKIKPFVPNTVNAMINQTIDLSCEVYANPAATIQWVIMQGLQIIDSSKF---------IAKIRPDMDGPLICEAKNYLGSTKETVQLNVLRDPLIHIDSNYR-VPKNSNYSINCRVTSNPPPEFIKWYKLSNMT---------DSSAVLISDDAKLNFILIDRSSTGMYACVTQNIQISTTGKRKPANSEKTMFLTVTYKPKEPQILGNKIISIMKGEKFIIKCSTDRKSPGEPFPTLKWIDVETKDIVSDME-------TFQVINSESRHNGKYKCLAENEIGKS 1568 + G +C N G + L + +P P + + + + CEV+ +P T++W G + S+F + ++ +G C +N +G + + L V P + + V + + + C T NPPP W + + SS +S L + RS +G Y C ++ S K A E L + P Q N+ +++ G ++ C ++ G P P++ W+ +K + T + + + G Y C+A + G++ Sbjct: 196 DAGMYVCVGTNMVGERDSEPAELAVFERPTFA-RKPMNLVMLADSDAEFRCEVHGDPPPTVRWRKEDG-DLPKGSRFEIQDDYTLRVERVGGTDEGTYTCVGENRVGKAEASASLVVHAPPQFVVRPRDQIVAQGQSATFLCETTGNPPPAVF-WQREGSQNLLFPNQPSQPSSRFSVSQTGHLTITDVQRSDSGYYTCQALSVAGSILAK---ALLEVGDALADSPPPIIRQGPANQTLAV--GSVALLAC----QAMGMPTPSVHWLKDGSKLSLGSARLGLQSGGTLSIKDVQLMDAGLYTCVAVSPSGET 497
BLAST of hemicentin-1 isoform X2 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000008186.1 (pep scaffold:Pmarinus_7.0:GL476501:83598:168579:1 gene:ENSPMAG00000007342.1 transcript:ENSPMAT00000008186.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 88.1965 bits (217), Expect = 1.055e-17 Identity = 181/873 (20.73%), Postives = 316/873 (36.20%), Query Frame = 3 Query: 357 SRLTIHNISSDNSGYYVCRV----TLLTTSEHIISLAVVTVKTPPKSISFHFNKSINVFQEQEFIAIQCSVSGGIPPPKISMYIVKDNAIKRLKIISSNFPNSTIAEVSAISLWR----PHYLENRGFVMCTAINDAGVLTKNTSLLNIK-YKPKIKPFVPNTVNAMINQTIDLSCEVYANPAATIQWVI------------MQGLQIIDSSKF-----IAKIRPDMDGPLICEAKNYLGSTKETVQLNVLRDPLIHIDSNYRVPKNSNYSINCRVTSNPPPEFIKWYKLSN-MTDSSAVLISDDAKLNFILIDRS-STGMYACVTQNIQISTTGKRKPANSEKTMFLTVTYKPKEPQILGN-KIISIMKGEKFIIKCS-TDRKSP--------GEPFPTLKWIDVETKDIVSDMETFQVINSESRHNGKYKCLAENEIGKSFSRETALVTVNEAPSIITQHKNRKVFLSYSDLPQSISFTCEFRGQPLYEARWRYGNEKIPPSSQDFKIEDHRNISNERISQIFTKLT-IDLYSRTFSQQTSLRSSPNGRYNCEADNRHGIASLDYFLXXXXXXXXXXNIRHRKIAASLNQNVVMIRCQAESISTMHIKWYKTNEHIVLPFQSKKYSIFEAEVTKYEPERDLFTPGLKVNELTIKDLENDDFSNYSCVASNDQGIKKVNFEVVFKSQPDPPYDLRVTDFEWDSVTINWKPGFNGGLTQNYEILVISENFGTQNVPFYSDKNE-------NTLTITGLYPSTPYEIRIYAVNSIGRSLNSETVKCVTKRIRKFDKIQAKILSDQPKIAVIIQEPDVCANLEYTRD--NGHQWFSILHC--IRFNASHINETVL--LDIIRVASILDLQSGLIH 2819 S L I + + ++SG YVC V + S + A V V+ P + + + EF C VSG ++ + D P + A VS R + G C A + G ++ S+L ++ PKI V + L C V +P TI W + +G I+ + R G C+A N G + ++NV P I N ++CRV P I+W + + + + + L + + G Y C +Q A+ +++ +TV KEP ++ ++ ++ +G++ + C SP G+P P VET + +S + + N HNG Y CLA NE + S + L+ V P + Q K++ + + C G P+ + W+Y P Q R F L L R ++ G Y C+ N G L+ P + + + +A + ++C A + I+W K E ++ P + +Y ++ + T ++ L I D ++C A N G + ++ + PDPP ++ V + ++T+ W GF+G N I + ++ + + N TI L+P+T Y R+YA N IG S S+ + T+ + D P + VI+ EP ++ T +GH ++ I + + L +I+R+ S + +S L+H Sbjct: 109 SGLVITDTTVEDSGAYVCEVWNSFGVAAVSGRLTIKAPVVVRVDPHRLKTTLSGTA------EF---SCEVSGAAGDGMVTWFHNGD-------------PPTPTASVSGAQGERLSVHAAGRSDGGTYQCVARGEGGDTAQDFSILMLEDGSPKIASSFSERV-VSPGEPFSLQCVVRGSPPPTIAWTLDGEPALSRDAPHRRGNHIVTPGDVTGYLNVTGARVTDGGVYRCQAGNAAGQAEYQARINVRGSPSIRPMRNVTAIAGREAYLHCRVIGYPY-YSIRWLREGTPLPYNHRQTVFANGTLRLADVQKGMDEGAYICSVL-VQPG-------ASPSRSLIVTV----KEPPLIQPFEMPAVTQGQRVYVPCVIVSGDSPIRITWHKDGQPLPPRLGAQVETTEFIS---SLLIPNVTQLHNGNYTCLARNE-AATVSHGSQLI-VRVPPRFVVQPKDQDGIFG-----KPVVLNCSADGYPIPKIIWKYSKGNGNPQFQPVLSGGGR----------FQPLGNGSLLLRQVQEED------GGFYLCQVSNGVGTDISKSMLLNVKIPALVTSQANVTLATRGQHS--NLQCSARGERPIIIRWEK-EETLIDPERMFRYVVYTQD-----------TGDELLSTLQILPTVRGDSGFFTCHAINSYGEDRGLIQLTVQEPPDPP-EVEVREVNARTITLRWTSGFDG----NSPITAFDIEYKNRSDTWEQKQRTKDISSTINQATIIDLHPATHYVFRVYAKNRIGASEPSKDLPITTQ----------EAAPDGPPLEVIL-EPQSSQSIRVTWKVPHGHLRNGVIRGYQIGYREAEPGSGALSQFNIVRLESTGERESCLLH 889
BLAST of hemicentin-1 isoform X2 vs. Ensembl Sea Lamprey
Match: cntn3b (contactin 3b [Source:ZFIN;Acc:ZDB-GENE-130530-645]) HSP 1 Score: 70.0922 bits (170), Expect = 2.668e-12 Identity = 126/605 (20.83%), Postives = 222/605 (36.69%), Query Frame = 3 Query: 966 PLICEAKNYLGSTKETVQLNVLRDPLIHIDSNYRVPKNSNYSINCRVTSNPPPEFIKWYKLSNMTDSSAVLISDDAKLNFILIDRSSTGMYACVTQNIQISTTGKRKPANSEKTMFLTVTYKPKEPQILGNKIISIMKGEKFIIKCSTDRKSPGEPFPTLKW----IDVETKDIVSDMETFQVINSESR--HNGKYKCLAENEIGKSFSRETALVTVNEAPSIITQHKNRKVFLSYSDLPQSISFTCEFRGQPLYEARWRYGNEKIPPSSQDFKIEDHRNISNERISQIFTKLTIDLYSRTFSQQTSLRSSPNGRYNCEADNRHGIA--SLDYFLXXXXXXXXXXNIRHRKIAASLNQNVVMIRCQAESISTMHIK--WYKTNEHIVLPFQSKKYSIFEAEVTKYEPERDLFTPGLKVNELTIKDLENDDFSNYSCVASNDQGIKKVNFEVVFKSQPDPPYDLRVTDFEWDSVTINWKPGFNGG---LTQNYEILVISENFGTQNV---PFYSDKNENTLTITGLYPSTPYEIRIYAVNSIGRSLNSETVKCVT----------KRIRKFDKIQAK-ILSDQPKIAVIIQEPDVCANLEYTRDNG 2699 PL+ ++ +G + +++ P H + V + C NP P I W K+ S A L+ +A L G Y C +N+ + + K +TV P Q + N I G+K C K+ G+P PT +W + + ++ S M ++I E + G Y+CLAEN+ G+ +S V + AP + R + Q++ CE + P W GN + + NER+S L+ R+ + + + G Y C +N G A + L + +++ + S ++ CQA ++ I W + I + ++ Y + + ++ DL IK L+ NY+C A ++ + P PP + + +V + WK G N ++ + + G NV P + T+ GL P YE + A+N++G S S + + +R+ Q + +++ QP PDV L + R+NG Sbjct: 193 PLLIKSGRSMGEYEPRIEVGF--SPKTHTLLGHTV------RLECFALGNPVP-VISWRKIDGQLPSKAYLMEANAVLEIPNFQHEDGGNYECNAENVAGKNSAQGK---------ITVYAPPHWIQPISNVEQGI--GDKLSWDC----KAGGKPPPTYRWLRNGVPLPSESRFSVMANGELILQELQPWDRGMYQCLAENKHGRIYSHGELRVKAS-APDFRSNPLKRVTPAARGG--QAV-IKCEPKAWPRPSFTWTKGNAMV--------------MDNERMS---ITQNGSLWIRSVTDEDA------GTYTCTVENHLGSANSTGRLILKESTRITVVPSLKMVSVGES-----IVWPCQASHDPSLDIVFVWSLNGQRIDMEKDAEHYQLLQGSKSQ---TSDL---------ALIKRLQLRHRGNYTCTAQTSVDNTSAWAMLMVRGPPGPPGAVVAEEATSTTVRLTWKRGSNNHSPIISYKIQARAPVASTGWLNVHTSPDIISGDSEQATVVGLTPWMDYEFTVLAINALGESEASRPSRMIKTQSAGPELAPERLGGGGGHQHELVITWQPVAPQFQYGPDVGYTLAF-RENG 728 HSP 2 Score: 51.9878 bits (123), Expect = 9.933e-7 Identity = 62/288 (21.53%), Postives = 107/288 (37.15%), Query Frame = 3 Query: 780 KYKPKIK-PFVPNTVNAMINQTIDLSCEVYANPAATIQWVIMQG-------LQIIDSSKFIAKIRPDMDGPLICEAKNYLGSTKETVQLNVLRDP-LIHIDSNYRVPKNSNYSINCRVTSNPPPEFIKWYKLS-NMTDSSAVLISDDAKLNFILIDRSSTGMYACVTQN--IQISTTGKRKPANSEKTMFLTVTYKPKEPQILGN---KIISIMKGEKFIIKCSTDRKSPGEPFPTLKWIDVETKDIVSDMETFQVINSES--------RHNGKYKCLAENEIGKSFS 1574 +Y+P+I+ F P T + ++ T+ L C NP I W + G L ++ I + + G C A+N G ++ V P I SN S +C+ PPP + +W + + S + + +L + GMY C+ +N +I + G+ + K P N ++ +G + +IKC + P P+ W + +V D E + + S G Y C EN +G + S Sbjct: 204 EYEPRIEVGFSPKT-HTLLGHTVRLECFALGNPVPVISWRKIDGQLPSKAYLMEANAVLEIPNFQHEDGGNYECNAENVAGKNSAQGKITVYAPPHWIQPISNVEQGIGDKLSWDCKAGGKPPPTY-RWLRNGVPLPSESRFSVMANGELILQELQPWDRGMYQCLAENKHGRIYSHGELR-------------VKASAPDFRSNPLKRVTPAARGGQAVIKC----EPKAWPRPSFTW--TKGNAMVMDNERMSITQNGSLWIRSVTDEDAGTYTCTVENHLGSANS 470
BLAST of hemicentin-1 isoform X2 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000002502.1 (pep scaffold:Pmarinus_7.0:GL476400:249000:366561:-1 gene:ENSPMAG00000002253.1 transcript:ENSPMAT00000002502.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 67.3958 bits (163), Expect = 2.467e-11 Identity = 168/760 (22.11%), Postives = 283/760 (37.24%), Query Frame = 3 Query: 360 RLTIHNISSDNSGYYVCRVTLLTTSEHIISLAVVTVKTPPKSISFHFNKSINVFQEQEFIA--IQCSVSGGIPPPKISMYIVKDNAIKRLKIISSNFPNSTIAEVSAISLWRPHYLENRGFVMCTAINDAGVLTKNTSLLNIKYKPKIKPFVP--NTVNAMINQTIDLSCEVYANPAATIQWV-----IMQG----LQIID--SSKFIAKIRPDMDGPLICEAKNYLGSTKETVQLNVLRDPLI--HIDSNYRVPKNSNYSINCRVTSNPPPEFIKWYKLSNMTDSSA----VLISDDAKLNFILIDRSSTGMYACVTQNIQISTT-GKRKPANSEKTMFLTVTYKPKEPQILGNKIISIMKGEKFIIKCSTDRKSPGEPFPTLKWID----VETKD----IVSDME-TFQVINSESRHNGKYKCLAENEIGKSFSRETALVTVNEAPSIITQHKNRKVFLSYSDLPQSISFTCEFRGQPLYEARWRYGNEKIPPSSQDFKIEDHRNISNERISQIFTKLTIDLYSRTFSQQTSLRSSPNGRYNCEADNRHGIASLDYFLXXXXXXXXXXNIRHRKIAASLNQNVVMIRCQAESISTMHIKWYKTNEHIVLPFQSKKYSI-FEAEVTKYEPERDLFTPGLKVNELTIKDLENDDFSNYSCVASNDQGIKKVNFEVVFKSQPDPPYDLRVTDFEWDSVTINWKPGFNGGLTQNYEILVISENFGTQNVPFYSDKNENTLTITGLYPSTPYEIRIYAVNSIG 2543 RL + G Y C+ T T S+H + V +T P F++ + + ++ +C V+G P + KDN R N+ + + + +++ + + G C A N A T+ L++K +P FV T +A ++ T L C++ + ++ W I QG + ++ ++ I K+ C+A N GS T L V+ P ++S + VP ++ V S P +KW++ N S ++ A L +D +S G+Y+C N S T +E+ F + K+ Q + GE + S G P + W +E D +S+ E T +V+N + G Y C +NE G+ T L T+ E P+ I + ++ + ++ C+ G P W G++K+ S K+ N++ T++L SL + G Y+C+A+N G A+ L + Y R K ++ C+ WYK H V + Y I E V + T E T + +D + SC A + KKV F+ +PDP FE + + +P L N EI + G + FY + T+ G S Y + AVN +G Sbjct: 5082 RLIVMKTDRSEGGVYTCKATNETGSDHCSTQLEVKERTIPPD----FDEKLESLEVTAGLSADFECHVTGSAP---FRVTWTKDNRDIR---SGGNYKFTFLDNTAHLTILKADK-GDIGTYTCKAANAA-GSAACTADLSVKDRPVAPSFVRKLKTTDAALSSTAHLECKLSGSVPISVVWFKGSEEIAQGERYKMTFVENVATLEIQKVVASDAFSYTCKATNVSGSEASTADLKVIEPPSFTKTVESQHVVP-GASVEFKSSV-SGTEPLTVKWFRDDNELMSGRRCKITFLNGVATLKLDDVDAASAGVYSCQVSNAAASETCSANLTVKAERANF---RRRVKDSQ--------VSNGETAVFSTSFS----GTPEIVVFWYKQNNLIEESDKYRVAISEGESTLEVLNVDKSDEGIYTCKIQNEAGEDSCLAT-LATL-EPPNFIKGLEPTEIVVG-----STVHLECQVAGTPQIRVSWYKGSQKL-KSGDKCKMAFKNNLA-----------TLELR--------SLTKADTGDYSCKAENDFGSATSLASLSVSERKNPPYFTRKLKDWQAVEGTAATFDCRVTGTPPFSFIWYK---HGVELSSGEDYVISAEENVATLDIHNVKLT---HAGEYTCRVF--NDVDSASCSAKLEAKDKKV--PPSFEKKPDPVEVTAGESFELECLIAGSRPIRISWLKNNREI----RSVGNYKLFFYDNAARLTVLKAGKEDSGTYVCK--AVNEVG 5769 HSP 2 Score: 63.5438 bits (153), Expect = 3.491e-10 Identity = 146/692 (21.10%), Postives = 256/692 (36.99%), Query Frame = 3 Query: 363 LTIHNISSDNSGYYVCRVT-LLTTSEHIISLAVVTVKTPPKSISFHFNKSINVFQEQEFIAIQCSVSGGIPPPKISMYIVKDNAIKRLKIISSNFPNSTIAEVSAISLWRPHYLENRGFVMCTAINDAGVLTKNTSLLNIKYKPKIKPFVPN---TVNAMINQTIDLSCEVYANPAATIQW---------------VIMQGLQIIDSSKFIAKIRPDMDGPLICEAKNYLGSTKETVQLNVLRDPLIHIDSNYRVPK-----NSNYSINCRVTSNPPPEFIKWYK----LSNMTDSSAVLISDDAKLNFILIDRSSTGMYACVTQNIQISTTGKRKPANSEKTMFLTVTYKPKEPQILGNKIISIMKGEKFIIKCSTDRKSPGEPFPTLKWI--DVETKDIVSDMETFQ-------VINSESRHNGKYKCLAENEIGKSFSRETALVTVNEAPSIITQHKNRKVFLSYSDL----PQSISFTCEFRGQPLYEARWRYGNEKIPPSSQDFKIEDHRNISNERISQIFTKLTIDLYSRTFSQQTSLRSSPNGRYNCEADNRHGIASLDYFLXXXXXXXXXXNIRHRKIAASLNQNVVMIRCQAESISTMHIKWYKTNEHIVLPFQSKKYSIFEAEVTKYEPERDLFTPGLKVNELTIKDLENDDFSNYSCVASNDQGIKKVNFEVVFKSQPDPP 2315 L I N+++++ Y C V+ + SL V K PP SF + E + C V+G PP KIS +KDN R +N+ S + +++ + ++ G +C A N+AG T + + + IK + ++ P ++N + +L C V + + W + M+ + + I K+ G C A N +GS + ++ V +D + ++ K +S ++CRV P + W K + + + + A L + +D+S G Y C N+ + + E FL EPQ ++ G + +C+ S EP +KW + E + +S +F+ V + G+Y C N GK+ + V + P+ K F SDL S SF C F G P W + +I + H+ +++ + + T+D+ + S +G Y C+ N G + L + PP ++ + + V CQ + + WYK ++ + KY + +F V L +K+ E D YSC A N G K + + K + PP Sbjct: 6114 LEILNLATNDEEEYSCTVSNDVGKISCAASLEVKERKNPP---SFDQQLAPASVTAGEPADLGCHVTGS-PPFKISW--LKDNKEIR---PGTNYKFSFVDNTPLLTILKTDKRDS-GVYVCRAANEAGYDT-SCAPVTIKER-RVAPTFDQKLESLNVTTGERAELECHVTGSVPIKVTWAKDNREIRAAGNYRMIFMENIARLT----ILKVGKLDSGIYTCAASNDVGSDVTSTEITV-KDQAVPPSFVRKLKKTDAILHSTAQMDCRVAGTVPI-LVAWSKNGVEIVDGDKYRCLFEENTASLEILKVDKSDDGSYTCTATNVAGRDSCSTTLSIIEPPSFLM----KMEPQ-------EVLSGSRATFQCAV---SGTEPL-LVKWYKGNQELRTDISHSISFRDSVALLIVEKVKLAFAGEYSCQVSNSAGKTSCSASLFV---KEPA--------KFFSKPSDLDVKAGDSASFICSFVGTPKIAVNWYKEDNQI--------VAGHKF----QVTTVEGQSTLDILATEISD--------SGNYTCKIQNDSGQDNCTALLKVLDPPYFVKSLEPMEGTFGTS---VYFECQVAGAPEIRVTWYKGSQKL----SGAKY-------------KTMFQHNTAV--LEVKNFEKADVGTYSCEAENSLGSAKTSASLAGKERKHPP 6719 HSP 3 Score: 60.077 bits (144), Expect = 4.002e-9 Identity = 119/563 (21.14%), Postives = 204/563 (36.23%), Query Frame = 3 Query: 699 LENRGFVMCTAINDAGVLTKNTSLLNIKYKPK-IKPFVPNTVNAMINQTIDLSCEVYANPAATIQW------VIMQG------------LQIIDSSKFIAKIRPDMDGPLICEAKNYLGSTKETVQLNV-----LRDPLIHIDSNYRVPKNSNYSINCRVTSNPPPEFIKWYK----LSNMTDSSAVLISDDAKLNFILIDRSSTGMYACVTQNIQISTTGKRKPANSEKTMFLTVTYKPKEPQILGNKIIS--IMKGEKFIIKCSTDRKSPGEPFPTLKWIDVETKDIVSD----------METFQVINSESRHNGKYKCLAENEIGKSFSRETALVTVNEAPSIITQHKNRKVFLSYSDLPQSISFTCEFRGQPLYEARWRYGNEKIPPSSQDFKIEDHRNISNERISQIFTKLTIDLYSRTFSQQTSLRSSPNGRYNCEADNRHGIASLDYFLXXXXXXXXXXNIRHRKIAASLNQNVVMIRCQAESISTMHIKWYKTNEHIVLPFQSKKYSI-FEAEVTKYEPERDLFTPGLKVNELTIKDLENDDFSNYSCVASNDQG 2264 L + G +CTA ++AG + +S+ +K P ++ P A + L C + +P + W V G L+I DS + CEA+N +G+ T ++V + PL + V NS+ ++ + +PP + +KW K L + A L + A L + G Y+C +N GK + K KEP K I+ + +G + + P T+ W + K I D ++ +E H G+Y C A+NE G +A+++V E + + + ++ V + + F C G RWR +E + SS+ FK+ N+++ ++ ++ D + G Y CE N G + + L I + +R K + ++ C+ S + + W+K E I S K+ I FE K E I + D Y+C A N G Sbjct: 4314 LADTGDYVCTASSEAGSESTASSV-EVKADPAGLRALQPEVKEA--KGLVHLDCSLKGSPVIKVTWFKNDNEVKADGRVQLSFVNNVAVLEIRDS-------ETEDSADYTCEAQNEVGTVSCTCAVSVKEIPSFKKPL----ESMEVRGNSDVTLEVELDGSPPFD-VKWVKNARELPKIDKYRAKLENTTATLRIGNFSAADVGQYSCKVKN----NVGKDESH---------ANIKLKEPPKFTKKFINSEVSEGSSATLNATLIGSQP----MTIAWSKDKLK-IAEDENHSISYKDNHAILTIVKAEKSHAGEYTCDAKNEAGAQSC--SAVLSVKEPATFVDKMESVNVTVG-----EVAFFECRVAGSVPITVRWRKDHELL-KSSKKFKMTFTNNVASLKL------MSTDKFD-------------TGEYYCEVQNDGGSSICNATLTILDRIVPPTFVRKLKNGDCVLHAKAVLECKLAGSSPLTVSWFKGVEEIS---DSDKFKISFEDNTAKVE----------------ILNASQVDEGTYTCKADNAAG 4797 HSP 4 Score: 58.151 bits (139), Expect = 1.524e-8 Identity = 152/692 (21.97%), Postives = 248/692 (35.84%), Query Frame = 3 Query: 363 LTIHNISSDNSGYYVCRVTLLTTSEHIISLAVVTVKTPPKSISFHFNKSINVFQEQEFIAIQCSVSGGIPPPKISM-YIVKDNAIKRLKIISSNFPNSTIAEVSAISLWRPHYLENRGFVMCTAINDAGVLTKNTSLLNIKYKPK-IKPFVPNTVNAMINQTIDLSCEVYANPAATIQWVIMQGLQIIDSSKFIAKIRPDMD------------GPLICEAKNYLGSTKETVQLNVLRDPLIHIDSNYRVPKNSNYSI------NCRVTSNPPPEFIKWY----KLSNMTDSSAVLISDD-AKLNFILIDRSSTGMYACVTQNIQISTTGKRKPANSEKTMFLTVTYKPKEPQILGNKIISIMKGEKFIIKCSTDRKSPGEPFPTLKWIDVETKDI----------VSDMETFQVINSESRHNGKYKCLAENEIGK--SFSRETALVTVNEAPSIITQHKNRKVFLSYSDLPQSISFTCEFRGQPLYEARWRYGNEKIPPSSQDFKIEDHRNISNERISQIFTKLTIDLYSR-----TFSQQTSLRS------SPNGRYNCEADNRHGIASLDYFLXXXXXXXXXXNIRHRKIAASLNQNV----------VMIRCQAESISTMHIKWYKTNEHIVLPFQSKKYSIFEAEVTKYEPERDLFTPGLKVNELTIKDLENDDFSNYSCVASNDQG 2264 L + + +G Y C+V+ ++ A + VK P K S + + FI CS G PKI++ + +DN I + F +T+ S + + + + G C ND+G T+LL + P +K P + ++ C+V P + W +G Q + +K+ + + G CEA+N LGS K + L H S R+ KN I + RVT PP + W+ +LS +D + D+ A L+ + S G Y C N S + K +E+ KP Q L + + + G+ ++C P + F W+ + KDI + + + +G+Y C A N+IG S + ETA+ RKV ++ P I E +G L D R ++ I+ +TK DL++ +F +L S S +G Y C+A+N G A+ L NI+ RK A + ++ V + C+ + I W K + V PF + E + T L I + D Y+C A N+ G Sbjct: 6495 LIVEKVKLAFAGEYSCQVS--NSAGKTSCSASLFVKEPAKFFSKPSDLDVKAGDSASFI---CSFVG---TPKIAVNWYKEDNQI----VAGHKFQVTTVEGQSTLDILATE-ISDSGNYTCKIQNDSG-QDNCTALLKVLDPPYFVKSLEP--MEGTFGTSVYFECQVAGAPEIRVTW--YKGSQKLSGAKYKTMFQHNTAVLEVKNFEKADVGTYSCEAENSLGSAKTSASLAGKERK--HPPSFSRMLKNMQQVIGDCAKFDARVTGTPPF-HVSWFLGDSELS-YSDKHVISFEDNVASLSIFSLKVSDAGEYTCKVSNEDGSISCSAKLDVTERKT------KPTFDQKL--EPVEAVVGDPAELECHLTGSLPIKIF----WMK-DKKDIRPGPNCKMTFFDNTPHLTIYKLDKSDSGEYTCKAVNDIGSDNSCTCETAIA-------------ERKVAPMFTKKPLEILDEEEGKGVKL----------------------DSRVSGSQPIAITWTKDDKDLHAHPGRELSFKNNIALMSLKSTKVSDSGLYVCKAENEAGTATFKVTL----------NIKERKHAPNFDKKVQSLTVVEGDTLSASCRVSGSEPLQIMWLKDRKE-VQPFGKVSIAYSEGDCT-----------------LEISQVTKADAGEYTCKAVNEAG 7088 HSP 5 Score: 55.0694 bits (131), Expect = 1.217e-7 Identity = 145/685 (21.17%), Postives = 244/685 (35.62%), Query Frame = 3 Query: 342 TISHESRLTIHNISSDNSGYYVCRVTLLTTSEHIISLAVVTVKTPPKSISFHFNKSINVFQE---QEFIAIQCSVSGGIPPPKISM-YIVKDNAIKRLKIISSNF-PNSTIAEVSAISLWRPHYLENRGFVMCTAINDAGVLTKNTSLLNIKYKPKIKPFVPNTVNAMINQTIDLSCEVYANPAATIQW-----VIMQGLQIIDSSKF------IAKIRPDMDGPLICEAKNYLGSTKETVQLNVL--RDPLIHID--SNYRVPKNSNYSINCRVTSNPPPEFIKWYKLS-NMTDSSAVLISDDAKLNFILIDRSSTG---MYACVTQNIQISTTGKRKPANSEKTMFLTVTYKPKEPQILGNKI--ISIMKGEKFIIKCSTDRKSPGEPFPTLKWIDVETKDI----------VSDMETFQVINSESRHNGKYKCLAENEIGKSFSRETALVTVNEAPSIITQHKNRKVFLSYSDLPQSISFT--------CEFRGQPLYEARWRYGNEKIPPSSQDFKIEDHRNISNERISQIFTKLTIDLYSRTFSQQTSLRSSPNGRYNCEADNRHGIASLDYFLXXXXXXXXXXNIRHRKIAASLNQNVVMIRCQAESISTMHIKWYKTNEHIVLPFQSKKYSIFEAEVTKYEPERDLFTPGLKVNELTIKDLENDDFSNYSCVASNDQG 2264 T H L I + + G Y C+V + + ++ VT+ PP F+K++ +QE E++ Q V+G P +S+ + +K S +F N + E+S + + G C N AG+ T + L +K P +V L CEV P W +I GL K + ++ G +C+A+N +GS L V ++P + + + + +CR T PP + W+K +T +S + + F+ I +T Y+C N GK A S L V + K P ++ S+ GE + C G P + W+ + K+I V + ++ ++ R +G Y C A NE G + A VT+ E R+V ++ +S++ T C G + W N +I + ++R I E I+ +LTI + S G Y C A N G + +K + +R K ++ + + C+ + + W K IV KY E T L I ++ D +Y+C A+N G Sbjct: 5836 TSDHTVNLEILELGIADGGNYTCKVNNVAGKDSCSAILRVTIAEPP-----GFSKTLE-YQEVLLGEYVRFQSIVTGTEP---LSVKWFADSKELKPTDNCSISFRGNRALLELSQVD------SASAGEFTCQVANAAGIETCSAKLF-------VKVSEPGSVR--------LECEVAGTPVIKTSWFKDDVLITSGLNRKPVQKLNLAILELRNVQYSESGEYVCKAENDIGSATSVAMLTVTERKNPPVFTRKLKDVQGVEGGAAMFDCRATGTPPFA-VAWFKHGKEITPGEKYRMSFEENVVFLEILNLATNDEEEYSCTVSN----DVGKISCAAS-----LEVKER-KNPPSFDQQLAPASVTAGEPADLGCHV----TGSPPFKISWLK-DNKEIRPGTNYKFSFVDNTPLLTILKTDKRDSGVYVCRAANEAG--YDTSCAPVTIKE----------RRVAPTFDQKLESLNVTTGERAELECHVTGSVPIKVTWAKDNREIRAAG------NYRMIFMENIA----RLTILKVGKLDS----------GIYTCAASNDVGSDVTSTEITVKDQAVPPSFVRKLKKTDAILHSTAQMDCRVAGTVPILVAWSKNGVEIV---DGDKYRCLFEENTA---------------SLEILKVDKSDDGSYTCTATNVAG 6424 HSP 6 Score: 55.0694 bits (131), Expect = 1.501e-7 Identity = 158/747 (21.15%), Postives = 274/747 (36.68%), Query Frame = 3 Query: 363 LTIHNISSDNSGYYVCRVTLLTTSEHIISLAVVTVKTPPKSISFHFNKSINVFQEQEFIAIQCSVSGGIPPPKISMYIVKDNAIKRLKIISSNFPNSTIAEVSAISLWRPHYLENRGFVMCTAINDAGVLTKNTSLLNIKYKPKIKPFVPNTVNAMINQTIDLSCEVYANPAATIQW------------VIMQGLQIIDSSKFIAKIRPDMDGPLICEAKNYLGSTKETVQLNVLRD----PLIHIDSNYRVPKNSNYSINCRVTSNPPPEFIKWYK-LSNMTDSSAVLIS---DDAKLNFILIDRSSTGMYACVTQNIQISTTGKRKPANSEKTMFLTVTYKPKEPQILGNKIISIMKGEKFIIKCSTDRKSPGEPFPTLKWIDVET------------KDIVSDMETFQVINSESRHNGKYKCLAENEIGKSFSRETALVTVNEAPSIITQHKNRKVFLSYSDLPQSISFTCEFRGQPLYEARWRYGNEKIPPSSQDFKIEDHRNISNERISQIFTKLTIDLYSRTFSQQTSLRSSPN--------GRYNCEADNRHGIASLDYFLXXXXXXXXXXNIRHRKIAASLNQNVVMI----------RCQAESISTMHIKWYKTNEHIVLPFQSKKYSIFEAEVTKYEPERDLFTPGLKVNELTIKDLENDDFSNYSCVASNDQGIKKVNFEVVFKSQPDPP-YDLRVTDFEWDSVTINWKPGFNGGLTQNYEILVISENFGTQNVPF 2450 L I N S+ + G Y C+V + S A + +K PPK N ++ E + ++ G P +++ KD +LKI + + + AI + G C A N+AG + +++L++K +P +VN + + C V + T++W M + S K ++ + D G CE +N GS+ L +L + N ++ + C++ + P + W+K + ++DS IS + AK+ + + G Y C N + + K E F V KP+E L ++S T S +P ++KW T K++ + +E +V +S G+Y C N +G +A + V E T+ ++ V +L + SF C F G P RW +E++ S + FKI S+ + I T + YS S + S N G Y C A N G +S + LI ++ RK+A + +Q + + C + I W K N+ I Y I + T L + + + Y+C A+N+ G + ++ K + PP +D ++ E GL+ ++E V T + PF Sbjct: 4493 LRIGNFSAADVGQYSCKVKNNVGKDE--SHANIKLKEPPKFTKKFINSEVS---EGSSATLNATLIGSQP---MTIAWSKD----KLKIAEDENHSISYKDNHAILTIVKAEKSHAGEYTCDAKNEAGAQS-CSAVLSVK-EPATFVDKMESVNVTVGEVAFFECRVAGSVPITVRWRKDHELLKSSKKFKMTFTNNVASLKLMSTDKFDT-GEYYCEVQNDGGSSICNATLTILDRIVPPTFVRKLKNGDCVLHAKAVLECKLAGSSPLT-VSWFKGVEEISDSDKFKISFEDNTAKVEILNASQVDEGTYTCKADNAAGTDSCWAKVKVMEPPSFKEV-IKPQEA--LPGAVVSF-----------TSVVSGTDPL-SVKWFKDGTELLPSRNSRISFKNLSAVIELDKV---DSTAAGEYSCQVSNAVGTETC--SATLFVKEPAKFETKLQSTNV-----NLGDTASFNCTFTGTPEITVRWFRKDEELQDSDK-FKIVTTATSSSLEVLNI-TSDDVKPYSCRISNEAGEDSCINSLSVQADAGEYVCTAANEAGTSSCNANLI----------VKERKVAPTFDQKLQPVEVTAGDPSEFECHVTGSLPIKITWSKNNKEI---RSGGNYRITFLDNTP---------------RLIVMKTDRSEGGVYTCKATNETGSDHCSTQLEVKERTIPPDFDEKLESLE-----------VTAGLSADFECHV------TGSAPF 5151
BLAST of hemicentin-1 isoform X2 vs. Ensembl Sea Lamprey
Match: pxdn (peroxidasin [Source:ZFIN;Acc:ZDB-GENE-140415-2]) HSP 1 Score: 62.7734 bits (151), Expect = 5.422e-10 Identity = 87/412 (21.12%), Postives = 148/412 (35.92%), Query Frame = 3 Query: 1071 PKNSNYSINCRVTSNPPPEFIKWYKLSN---MTDSSAVLISDDAKLNFILIDRSSTGMYACVTQNIQISTTGKRKPANSEKTMFLTVTY--KPKEPQ-ILGNKIISIMKGEKFIIKCSTDRKSPGEPFPTLKWIDVETKDIVSDMETFQVINSESRH--------NGKYKCLAENEIGKSFSRETALVTVNEAPSIITQHKNRKVFLSYSDLPQSISFTCEFRGQPLYEARWRYGNEKIPPSSQDFKIEDHRNISNERISQIFTKLTIDLYSRTFSQQTSLRSSPNGRYNCEADNRHGIASLDYFLXXXXXXXXXXNIRHRKIAASLNQNVVMIRCQAESISTMHIKWYKTNEHIVLPFQSKKYSIFEAEVTKYEPERDLFTPGLKVNELTIKDLENDDFSNYSCVASNDQG 2264 P N+ Y + CR NP P I W SN M + + D L + G Y C+ +N+ A K + + Y P P ++ ++ GE ++CS G P P + W +++ + +D F V S H G+Y C A N + R +A + + AP I +++ V ++ + CE +G+PL W ++P S+ R++ + + T+ + Q G++ C+A N G+ L + +++ I ++ V I C A+ + W K HI +S K+ + AE L I+D D Y C+A N G Sbjct: 196 PGNTVY-LRCRAEGNPKPAII-WLHNSNEIAMAEDERRNLLQDGTLMIRDTRHTDQGTYQCMARNV----------AGEVKAPEVVLRYFDVPAPPTFVIQPHDTEVLVGESVTLECSAG----GHPAPRVSWTRDDSEQLPAD-PRFSVTASGGLHVERAGPGDEGRYTCHASNN--QDSIRASATILLKSAPQFILAPEDQVVTEGHT-----VDLHCEAQGRPLPVIAWTKAGSQLP--------------SDRRLT-VLSSGTLRIARVALHDQ--------GQFECQAVNVVGVRRAATQLTVLPRVTPVFSVTPSDITTDSGRD-VRIACSAQGEPQPSLMWAKDGVHIT---ESGKFHV-SAE-----------------GYLEIRDAGPADQGRYECIARNSIG 538 HSP 2 Score: 62.7734 bits (151), Expect = 5.514e-10 Identity = 67/307 (21.82%), Postives = 110/307 (35.83%), Query Frame = 3 Query: 705 NRGFVMCTAINDAGVLTKNTSLLNIKYKPKIKPFV--PNTVNAMINQTIDLSCEVYANPAATIQWVIMQGLQIIDSSKF---------IAKIRPDMDGPLICEAKNYLGSTKETVQLNVLRDP-LIHIDSNYRVPKNSNYSINCRVTSNPPPEFIKWYKLSNMTDSSAVL-ISDDAKLNFILIDRSSTGMYACVTQNIQISTTGKRKPANSEKTMFLTVTYKPKEPQILGNKIISIMKGEKFIIKCSTDRKSPGEPFPTLKW------IDVETKDIVSDMETFQVINSESRHNGKYKCLAENEIGKS 1568 ++G C A N AG + +L P FV P+ ++ +++ L C +PA + W Q+ +F + + P +G C A N S + + + + P I + V + ++C P P I W K + S L + L + G + C N+ G R+ A LTV + + I+ G I CS GEP P+L W I K VS ++ ++ G+Y+C+A N IG + Sbjct: 248 DQGTYQCMARNVAGEVKAPEVVLRYFDVPAPPTFVIQPHDTEVLVGESVTLECSAGGHPAPRVSWTRDDSEQLPADPRFSVTASGGLHVERAGPGDEGRYTCHASNNQDSIRASATILLKSAPQFILAPEDQVVTEGHTVDLHCEAQGRPLP-VIAWTKAGSQLPSDRRLTVLSSGTLRIARVALHDQGQFECQAVNV----VGVRRAATQ-----LTVLPRVTPVFSVTPSDITTDSGRDVRIACSAQ----GEPQPSLMWAKDGVHITESGKFHVSAEGYLEIRDAGPADQGRYECIARNSIGHA 540
BLAST of hemicentin-1 isoform X2 vs. Ensembl Nematostella
Match: EDO31942 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SWF5]) HSP 1 Score: 72.4034 bits (176), Expect = 6.424e-13 Identity = 90/369 (24.39%), Postives = 152/369 (41.19%), Query Frame = 3 Query: 498 FNKSINVFQEQEFIAIQCSVSGGIPPPKISMYIVKDNAIKRLKIISSNFPNSTIAEVSAISLWRPHYLENRGFVMCTAINDA--GVLTKNTSLLNIKYKPKIKPFVPNTVNAMINQTIDLSCEVYANPAATIQWVIMQGLQIIDSSKF-IAKIRPDMDGPLICEAKNYLGSTKETVQLN----VLRDPLIHIDSNYRVPKNSNYSINCRVTSNP-PPEFIKWYKLSNMTDSSAVLISDDAKLNFILIDRSSTGMYACVTQNIQISTTGKRKPANSEKTMFLTVTYKPKEPQILGNKIISIMKGEKFIIKCSTDRKSPGEPFPTLKWIDVETKDIVSDME-----TFQVINSESRHN-GKYKCLAENEIG 1562 ++S +V ++++F +I CS SG P P ++ ++ K +S P + + +SL + G C A ND G +T++ ++ N++Y P+I P TV A +TI L+C V NP ++ W Q + F A G +C A N + +T ++ V P I +S Y+ + S+ S+ P + W + + ++V SD + RS G Y C N S T T+ +TV YKP+ N S + ++C K+ G P P + W + I + + QV ++ + G+YKC A N +G Sbjct: 8 LDRSRDVAEDKDF-SITCSASG-RPAPNVT-WVNK----------TSGSPVAHGTGSAILSLLKIQ-RHQAGVYQCQATNDVKRGAITQDFTI-NVQYPPEITPIQNTTVRA--GETITLTCAVAGNPTPSVSWSKAGSGQSTGGNVFNEAGATKAETGQYVCTAVNIVSGNTQTKTVSTYVIVKYKPSIIANSPYQTVNETTGSLKLSCISDGYPAPMVTWSRDGVVVSPTSVYYSDS-------VTRSEAGTYTCTATNEMGSDT---------NTVQVTVNYKPEMASSTTN--TSSWNRKVLSLQC----KARGVPLPQITWYKPGGQPITAGVSPISGGQLQVTTTQDSGDYGQYKCRASNLLG 337 HSP 2 Score: 64.6994 bits (156), Expect = 1.655e-10 Identity = 104/502 (20.72%), Postives = 184/502 (36.65%), Query Frame = 3 Query: 1050 IDSNYRVPKNSNYSINCRVTSNPPPEFIKWYKLSNMTDSSAVLISDDAKLNFILIDRSSTGMYACVTQNIQISTTGKRKPANSEKTMFLTVTYKPKEPQILGNKIISIMKGEKFIIKCSTDRKSPGEPFPTLKWIDVETKDIVSDMETFQVINSESRHNGKYKCLAENEIGKSFSRET--ALVTVNEAPSIITQHKNRKVFLSYSDLPQSISFTCEFRGQPLYEARWRYGNEKIPPSSQDFKIEDHRNISNERISQIFTKLTIDLYSRTFSQQTSLRSSPNGRYNCEADNRHGIASLDYFLXXXXXXXXXXNIRHRKIAASLNQNVVMIRCQAESISTMHIKWYKTNEHIVLPFQSKKYSIFEAEVTKYEPERDLFTPGLKVNELTIKDLENDDFSNYSCVASNDQGIKKVNFEVVFKSQPDPPYDLRVTDFEWDSVTINWKPGFNGGLTQ--NYEILVISENFGTQNVPFYSDKNENTLTITGLYPSTPYEIRIYAVNSIG 2543 +D + V ++ ++SI C + P P + W ++ + S + A L+ + I R G+Y C Q + KR + T + V Y P+I + ++ GE + C+ G P P++ W + + F + G+Y C A N + + +T V V PSII + + ++ S+ +C G P W + P+S + S+ S G Y C A N G + + + Y P + + + +S N+ V+ ++C+A + I WYK + A V+ G ++ T +D + D+ Y C ASN G V P PP + V++ E S+ +NW P + G + +Y++ V P + I+GL +T Y +++ A N +G Sbjct: 8 LDRSRDVAEDKDFSITCSASGRPAPN-VTW--VNKTSGSPVAHGTGSAILSLLKIQRHQAGVYQC-----QATNDVKRGAITQDFT--INVQYP---PEITPIQNTTVRAGETITLTCAVA----GNPTPSVSWSKAGSGQ-STGGNVFNEAGATKAETGQYVCTAVNIVSGNTQTKTVSTYVIVKYKPSIIANSP----YQTVNETTGSLKLSCISDGYPAPMVTWSRDGVVVSPTSVYYS-------------------------------DSVTRSEAGTYTCTATNEMGSDTNTVQVTVNYKPEMASSTTN---TSSWNRKVLSLQCKARGVPLPQITWYKPGGQPIT-----------AGVSPIS--------GGQLQVTTTQD--SGDYGQYKCRASNLLGSVGRLIYVTQWFSPGPPI-IIVSNIEASSIKVNWAPPSSDGGSPVIDYKVEVDPAK------PPREGVAGGPVVISGLTKNTEYTVKVTARNVVG 425 HSP 3 Score: 63.1586 bits (152), Expect = 4.879e-10 Identity = 76/330 (23.03%), Postives = 123/330 (37.27%), Query Frame = 3 Query: 789 PKIKPFVPNTVNAMINQTIDLSCEVYANPAATIQWV-IMQGLQIIDSSK----FIAKIRPDMDGPLICEAKNYL--GSTKETVQLNVLRDPLIHIDSNYRVPKNSNYSINCRVTSNPPPEFIKWYKLSNMTDSSAVLISDDAKLNFILIDRSSTGMYACVTQNIQISTTGKRKPANSEKTMFLTVTYKPK----EPQILGNKIISIMKGEKFIIKCSTDRKSPGEPFPTLKWIDVETKD--IVSDMETFQVINSESRHNGKYKCLAENEIGKSFSRETALVTVNEAPSII-----TQHKNRKVFLSYSDLPQSISFTCEFRGQPLYEARW 1724 P P + + + ++ ++C PA + WV G + + + KI+ G C+A N + G+ + +NV P I N V ++ C V NP P + W K + + + ++ ++ TG Y C NI T + + ++ V YKP P N+ +K + C +D G P P + W ++D +VS + + G Y C A NE+G + T VTVN P + T NRKV +S C+ RG PL + W Sbjct: 2 PAFNPPLDRSRDVAEDKDFSITCSASGRPAPNVTWVNKTSGSPVAHGTGSAILSLLKIQRHQAGVYQCQATNDVKRGAITQDFTINVQYPPEITPIQNTTVRAGETITLTCAVAGNPTPS-VSWSKAGSGQSTGGNVFNEAGAT------KAETGQYVCTAVNIVSGNTQTKT-----VSTYVIVKYKPSIIANSPYQTVNETTGSLK-----LSCISD----GYPAPMVTW----SRDGVVVSPTSVYYSDSVTRSEAGTYTCTATNEMGSDTN--TVQVTVNYKPEMASSTTNTSSWNRKV----------LSLQCKARGVPLPQITW 294
BLAST of hemicentin-1 isoform X2 vs. Ensembl Nematostella
Match: EDO32297 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SVH5]) HSP 1 Score: 65.0846 bits (157), Expect = 2.085e-11 Identity = 62/247 (25.10%), Postives = 105/247 (42.51%), Query Frame = 3 Query: 564 GIPPPKISMYIVKD---NAIKRLKIISSNFPNSTIAEVSAISLWRPHYLENRGFVMCTAINDAGVLTKNTSLLNIKYKPKIKPFVPNTVNAMINQTIDLSCEVYANPAATIQWV-----IMQGLQI----IDSSKFIAKIRPDMDGPLICEAKNYLGSTKETVQLNVLR-DPLIH---IDSNYRVPKNSNYSINCRVTSNPPPEFIKWYKLSNMTDSSAVLISDDAKLNFILIDRSSTGMYACVTQN 1256 G+P P +S D + + + +S++ N TI + + G +CTA N GV + ++L +K PF V +++ ++++C V P +I W+ + Q + + + + ++ I G +C A N LG+ T LNVL D L H I N +++ SI+C T NP P I W + + + S + + L + S TG Y CV N Sbjct: 9 GLPKPSVSWTRAGDKLSHWLASMGRVSTSNGNVTITQAEP---------NDAGMYLCTARNLLGVASARSTLY---FKGMFHPF---DVITLLSSNVEVTCPVRGFPLPSITWLKDGQPLKQSMTVKVNNLTGTLYLLSILERRAGLYMCVATNSLGAATATTTLNVLHYDSLSHALTIGDNLNTLISTSVSIHCNATGNPVPS-ITWSRSGALIEPSKRIKIMGSTLVIVGTLWSDTGSYECVASN 239
BLAST of hemicentin-1 isoform X2 vs. Ensembl Nematostella
Match: EDO32296 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SVH4]) HSP 1 Score: 62.003 bits (149), Expect = 8.361e-10 Identity = 77/326 (23.62%), Postives = 132/326 (40.49%), Query Frame = 3 Query: 711 GFVMCTAINDAGVLTKNTSLLNIKYKPKIKPFVPNTVNAMINQTIDLSCEVYANPAATIQWV------IMQGLQIIDSSKFIAK-IRPDMDGPLICEAKNYLG----STKETVQLNVL-RD-PL-------IHIDSNYRVPKNSNYSINCRVTSNPPPEFIKWYKLSN-MTDSSAVLISDDAKLNFILIDRSSTGMYAC----------VTQNIQISTTGKRKPANSEKTMFLTVTYKPKEPQILGNKIISIMKGEKFIIKCSTDRKSPGEPFPTLKWIDVETKDIVSDMETFQVINSESRHNGKYKCLAENEIGKSFSRETALVT 1595 G CTA N G N++ + +K V + + + + + + CEV P ++ WV + +G I D+ + + RP G C A N G S++ T++ V RD PL I N V S +I+C T P P I W K + + + + + L + S G++ C V+ NI++ TT K + ++ KP + +I G ++ + G + CS + G P P ++W++ K I + N S +G Y C+A N +G++ + VT Sbjct: 103 GRYTCTARNAFGKDNANSTTIPPGDGSPVKVSVGDNITVITDTPLLIDCEVSGIPFPSVVWVKDGRVLMGEGYVIFDNGTLVLRRARPADSGRYTCTANNSRGKDHISSQPTIERPVAPRDIPLGDGSPTIARIADNATVLTGSRLTIDCVATGVPKPSII-WRKDGRELIGAGSYMAPGNGSLLIQQVAASHHGVFTCTATNPVGEDSVSSNIRVRTTDKVEKSD----------MKPVDVRIGGQ--VTSLSGVDITLNCS----ARGLPPPDIEWMN-GGKMITVQGPRLVLRNVMSSDSGNYTCIASNVVGRASASTMVNVT 410 HSP 2 Score: 57.7658 bits (138), Expect = 1.588e-8 Identity = 79/372 (21.24%), Postives = 138/372 (37.10%), Query Frame = 3 Query: 711 GFVMCTAINDAGVLTKNTSLL----NIKYKPKIKPFVPNTVNAMINQTIDLSCEVYANPAATIQWVI----MQGLQIIDSSKFIAKIRPDMDGPLICEAKNYLG---STKETVQLNVLRDPLIHIDSNYRVPKNSNYSINCRVTSNPPPEFIKWYKLSNMTDSSAVLISDDAKLNFILIDRSSTGMYACVTQNIQISTTGKRKPANSEKTMFLTVTYKPKEPQILGNKI---ISIMKGEKFIIKCSTDRKSPGEPFPTLKWIDVETKDIVSDMETFQVINSE-------SRHNGKYKCLAENEIGK-SFS-----RETALVTVNEAPSIITQHKNRKVFLSYSDLPQSISFTCEFRGQPLYEARWRYGNEKI 1745 G +CTA+N G++ K+T+ + N +K KI N + M + + L C P TI W M+ + S + K+ G C A+N G + T+ + + N V ++ I+C V+ P P + W K + +I D+ L + +G Y C N + +P + P I +I +++ G + I C + G P P++ W + ++++ N + H+G + C A N +G+ S S R T V ++ + + + LS D I+ C RG P + W G + I Sbjct: 15 GRYVCTAVNAIGIIHKSTNYIVWYENRPFKTKIG----NNLTTMKGRKLTLICHATGRPRPTITWFRGGEEMRTKVTNNGSLILEKVSSSDIGRYTCTARNAFGKDNANSTTIPPGDGSPVKVSVGDNITVITDTPLLIDCEVSGIPFPSVV-WVKDGRVLMGEGYVIFDNGTLVLRRARPADSGRYTCTANNSRGKDHISSQPTIERPVAPRDIPLGDGSPTIA--RIADNATVLTGSRLTIDCV----ATGVPKPSIIWRK-DGRELIGAGSYMAPGNGSLLIQQVAASHHGVFTCTATNPVGEDSVSSNIRVRTTDKVEKSDMKPVDVRIGGQVTSLSGVD----ITLNCSARGLPPPDIEWMNGGKMI 370
BLAST of hemicentin-1 isoform X2 vs. Ensembl Nematostella
Match: EDO32299 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SVH7]) HSP 1 Score: 59.3066 bits (142), Expect = 2.162e-9 Identity = 67/262 (25.57%), Postives = 109/262 (41.60%), Query Frame = 3 Query: 840 TIDLSCEVYANPAATIQWVIMQGLQIIDSSKFIAK---------IRPDMDGPLICEAKNYLGSTKETVQLNVL----RDPLIHIDSNYRVPKNSNYSINCRVTSNPPPEFIKWYKLSNMTDSSAVLISD----DAKLNFILIDRSSTGMYACVTQNIQISTTGKRKPANSEKTMFLTVTYKPKEPQILGNKIISIMKGEKFIIKCSTDRKSPGEPFPTLKW-IDVE--TKDIVSDMETFQVI--NSESRHNGKYKCLAENEI 1559 T+ + C PA + W M + +F+ + ++ D G + C A+N G T +LNV+ + I I + RV + N I+C + P P + W + + S+A L D D +N IL S TG Y C N EK+ F+TVT +G I+++ G K +++C S G P P+ W ++ E K +D+ +++ +GKY+C A N I Sbjct: 6 TLTIICPTRGLPAPDVTWE-MNNTNVRPGGRFVVQEGTLTIRNLVKQDQ-GNIRCVARNAAGQDTATSKLNVIDGDGEEARITIGQDLRVVEKMNVRIHCPIVGFPKP-VVTWTRNNQDVRSNARLFVDPNTNDLLINNILT--SDTGQYICSAVN---------PIGEDEKSSFITVTAT------IGTT-ITLLAGAKLVLQC----PSTGVPLPSTSWSLNGEPLEKGGRADLRGTELVIPAVAGVDSGKYQCTASNVI 242
BLAST of hemicentin-1 isoform X2 vs. Ensembl Nematostella
Match: EDO29616 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T347]) HSP 1 Score: 60.4622 bits (145), Expect = 3.056e-9 Identity = 70/293 (23.89%), Postives = 110/293 (37.54%), Query Frame = 3 Query: 771 LNIKYKPKIKPFVPNTVNAMINQTIDLSCEVYANPAATIQWV-------IMQGLQIIDSSKFIAKIRPDMDGPLICEAKNYL--GSTKETVQLNVLRDPLIHIDSNYRVPKNSNYSINCRVTSNPPPEFIKWYKLSNMTDSSAVLISDDAKLNFILIDRSSTGMYACVTQNIQISTTGKRKPANSEKTMFLTVTYKP----KEPQILGNKIISIMKGEKFIIKCSTDRKSPGEPFPTLKWIDVETKDIVSDMETFQVINSESR-HNGKYKCLAENEIGKSFSRETALVTVNEA 1607 LN+K P + ++++ N + +C PA + WV + G ++ + KI+ G C+A N + G+ + V + V P I N V ++ C V NP P + W K + + + + + TG Y C N T R + ++ V YKP P N+ I +K + C +D G P PT+ W +V + NS +R G Y C A NE+G + T VTVN A Sbjct: 112 LNVKVAPAFTSSLSSSLDVAENDDVTNTCSASGRPAPNVTWVNKTSGSPVAHGTG--SATLSLLKIQRHQAGLYQCQAINDVGRGAITQDVTIIVQYPPEITPIQNTTVRAGETITLTCAVAGNPTPS-VSWSKAGSGHSTGGNVFTKAGATKAV------TGQYVCTAVNTVTGNTQTRT-----ASTYVMVKYKPSIISSYPGQTVNETIDFLK-----LTCISD----GYPAPTVTW---SRDGLVVSRTSVYYSNSVTRSEAGTYTCTATNEMGSDAT--TVQVTVNCA 376
BLAST of hemicentin-1 isoform X2 vs. Ensembl Medaka
Match: ENSORLT00000012598.2 (roundabout homolog 1 [Source:NCBI gene;Acc:101156600]) HSP 1 Score: 96.2857 bits (238), Expect = 1.653e-19 Identity = 147/660 (22.27%), Postives = 243/660 (36.82%), Query Frame = 3 Query: 738 DAGVLTKNTSLLNIKYKPKIKPFVPNTVNAMINQTIDLSCEVYANPAATIQWVI-------------MQGLQIIDSSKFIAKI------RPDMDGPLICEAKNYLG---STKETVQLNVLRDPLIHIDSNYRVPKNSNYSINCRVTSNPPPEFIKWYK-LSNMTDSSAVLISDDAKLNFILIDRSSTGMYACVTQNIQISTTGKRKPANSEKTMFLTVTYKPKEPQILGNKIISIMKGEKFIIKCSTDRKSPGEPFPTLKWIDVETK------DIVSDMETFQVINSESRHNGKYKCLAENEIGKSFSRETALVTVNEAPSIITQHKNRKVFLSYSDLPQSISFTCEFRGQPLYEARW-RYGNEKIPPSSQDFKIEDHRNISNERISQIFTKLTIDLYSRTFSQQTSLRSSPNGRYNCEADNRHGI-----------ASLDYFLXXXXXXXXXXNIRHRKIAASLNQNVVMIRCQAESISTMHIKWYKTNEHIVLPFQSKKYSIFEAEVTKYEPERDLFTPGLKVNELTIKDLENDDFSNYSCVASN--------------DQGIKKVNFEVVFKSQPDPPYDLRVTDFEWDSVTINWKPGFNG-GLTQNYEILVISENFGTQNVPFYSDKNENTLTITGLYPSTPYEIRIYAVNSIGRS 2549 D+ + K + L + P+I P+ + + L+C+ P T++W + + S F +I +PD DG +C A+NYLG S ++++ +LRD + V + C+ P I W K +N+ D + KL ++ G Y CV N+ G+R+ +E T+ T+ + ++ ++ E C G+P P ++W ++ +++ D T + S G Y C+ EN +GKS +A +TV+ P+ T +N+ V + ++++F CE G P W R G+E + F + + S +SQ+ + LTI T ++ S G Y+C+A N G A DY I + L ++V + CQ + W K + +VL + S+ E L I E D Y+C ASN + G+ K + V P P VT+ SVT++WK + L +Y I S G + V T + L P Y I AVN+ G S Sbjct: 53 DSNLGYKGSRLRQEDFPPRIVEH-PSDLIVSKGEPATLNCKAEGRPPPTVEWYKDGERVETDRDNPRSHRMLLPSGSLFFLRIIHGRRSKPD-DGSYVCVARNYLGQAISHNASLEVAILRDDFRQNPVDVMVAVGEPAVLECQPPRGHPEPTISWRKDGANLDDRDERITIRSGKLMITNTLKTDAGKYICVATNM----LGERESETAELTVLERPTFVKRPSSVV------VLTDESVEFHCVVH----GDPVPIVRWRRDDSDLPKGRFEVLVD-HTLIIRQVTSSDEGSYTCVVENMVGKS--EASASLTVHVPPAFATHPRNQVVSVG-----RTVTFQCEATGNPQPAIFWQREGSESLL-----FSYQPPQPFSRLSVSQMGS-LTI----------TDVQRSDAGFYSCQALNIAGSVITKALLEVSDAGSDYLPPIIKQGPSNQTV--------LVDSIVELGCQTAGTPPPTVHWKK--DGVVLSPADSRTSLTE------------------TGSLKIYHTELGDSGMYTCTASNPGGEASWTAFLQVQEFGVGKSDHPVENNMIPTAPSKPEVTNISQTSVTLSWKSSPDKEKLPTSYLIEAFSYTLGNRWVTLAEHVRAETFVLRNLKPGAVYLFMIRAVNTYGLS 644 HSP 2 Score: 71.2478 bits (173), Expect = 6.745e-12 Identity = 110/485 (22.68%), Postives = 183/485 (37.73%), Query Frame = 3 Query: 903 QGLQIIDSSKFIAKIRPDMDGPLICEAKNYLGST--KETVQLNVLRDPLIHIDSNYRVPKNSNYSINCRVTSNPPPEFIKWYKLSNMTDS------SAVLISDDAKLNFILI-----DRSSTGMYACVTQNIQISTTGKRKPANSE-KTMFLTVTYKPKEPQILGNKIISIMKGEKFIIKCSTDRKSPGEPFPTLKW------IDVETKDIVSDMETFQVINSESRHNGKYKCLAENEIGKSFSRETALVTVNEAPSIITQHKNRKVFLSYSDLPQSISFTCEFRGQPLYEARWRYGNEKIPPSSQDFKIEDHRNISNERISQIFTKLTIDLYSRTFSQQTSLRSSPNGRYNCEADNRHGIASLDYFLXXXXXXXXXXNIRHRKIAASLNQNVVMIRCQAESISTMHIKWYKTNEHIVLPFQSKKYSIFEAEVTKYEPERDLFTPGL-KVNELTIKDLENDDFSNYSCVASNDQG--IKKVNFEV 2288 QG + + + +K P+ D L Y GS +E ++ P S+ V K ++NC+ PPP ++WYK ++ S ++ L F+ I + G Y CV +N G+ N+ + L ++ ++ + GE +++C R G P PT+ W +D + I + N+ GKY C+A N +G+ S ETA +TV E P+ + + + V +S+ F C G P+ RWR + +P + + DH I I Q+ SS G Y C +N G + L + PP + R++ ++ V +C+A I W + E+ + Y+P + + ++ LTI D++ D YSC A N G I K EV Sbjct: 34 QGSREVSTKSPQSKTEPNQDSNL-----GYKGSRLRQEDFPPRIVEHP-----SDLIVSKGEPATLNCKAEGRPPPT-VEWYKDGERVETDRDNPRSHRMLLPSGSLFFLRIIHGRRSKPDDGSYVCVARNY----LGQAISHNASLEVAILRDDFRQNPVDVM------VAVGEPAVLECQPPR---GHPEPTISWRKDGANLDDRDERITIRSGKLMITNTLKTDAGKYICVATNMLGERES-ETAELTVLERPTFVKRPSSVVVLTD-----ESVEFHCVVHGDPVPIVRWRRDDSDLPKGRFEVLV-DHTLI----IRQV-------------------TSSDEGSYTCVVENMVGKSEASASLTVHVPPAFATHPRNQVVSVG---RTVTFQCEATGNPQPAIFWQREGS--------------ESLLFSYQPPQPFSRLSVSQMGSLTITDVQRSDAGFYSCQALNIAGSVITKALLEV 447
BLAST of hemicentin-1 isoform X2 vs. Ensembl Medaka
Match: robo1 (roundabout guidance receptor 1 [Source:NCBI gene;Acc:101157073]) HSP 1 Score: 92.4337 bits (228), Expect = 2.423e-18 Identity = 112/472 (23.73%), Postives = 178/472 (37.71%), Query Frame = 3 Query: 978 EAKNYLGSTKETVQLNVLRDPLIHIDSNYRVPKNSNYSINCRVTSNPPPEFIKWYKLSNMTDS------SAVLISDDAKLNFILI-----DRSSTGMYACVTQNIQISTTGKRKPANSE-KTMFLTVTYKPKEPQILGNKIISIMKGEKFIIKCSTDRKSPGEPFPTLKW------IDVETKDIVSDMETFQVINSESRHNGKYKCLAENEIGKSFSRETALVTVNEAPSIITQHKNRKVFLSYSDLPQSISFTCEFRGQPLYEARWRYGNEKIPPSSQDFKIEDHRNISNERISQIFTKLTIDLYSRTFSQQTSLRSSPNGRYNCEADNRHGIASLDYFLXXXXXXXXXXNIRHRKIAASLNQNVVMIRCQAESISTMHIKWYKTNEHIVL-----PFQSKKYSIFEAEVTKYEPERDLFTPGLKVNELTIKDLENDDFSNYSCVASNDQG--IKKVNFEV--VFKSQPDP 2312 E N LG T ++ ++ S+ V K ++NC+ P P ++WYK ++ S ++ L F+ I + G Y CV +N G+ N+ + L ++ ++ + GE +++C R G P PT+ W ID + I + N+ GKY C+ N +G+ S E A +TV E PS + + ++ V + QS+ F CE RG P+ RWR + ++P + + EDH T+ + L S+ G Y C A+N G A L + PP R++ + V +C+A I W + +L P S ++S+ + +LTI D E D YSC A N G I K EV V +P P Sbjct: 68 EEDNSLGYTGSRLRQEDTPPRIVEHPSDLIVSKGEPATLNCKAEGRPTPT-VEWYKDGERVETDRDNPRSQRMLLPSGSLFFLRIVHGRRSKPDEGSYVCVARNY----LGEAVSHNASLEVAILRDDFRQNPADVM------VAAGEPAVLECQPPR---GHPEPTISWKKDGVNIDDRDERITIRGGKLMITNARKSDAGKYVCVGTNMVGERDS-EVAELTVLERPSFVRRPGSQVVLVD-----QSVEFRCEARGDPVPTVRWRKDDGELPKGRYEIR-EDH---------------TLKIR--------RLTSADVGSYTCVAENMMGKAEASATLTVHVPPAFVVRPRNQVVGVG---RTVTFQCEATGNPQPAIFWQREGSQNLLFSYQPPQPSSRFSVSQ------------------TGDLTITDAERSDMGYYSCQALNIAGSVITKALLEVTDVVSDRPPP 474 HSP 2 Score: 58.5362 bits (140), Expect = 5.212e-8 Identity = 103/455 (22.64%), Postives = 167/455 (36.70%), Query Frame = 3 Query: 360 RLTIHNISSDNSGYYVC--RVTLLTTSEHIISLAVVTVKTPPKSISFHFNKSINVFQEQEFIAIQCSVSGGIPPPKISMY---IVKDNAIKRLKIISSNFPNSTIAEVSAISLWRPHYLENRGFVMCTAINDAGVLTKNTSLLNIKYKPKIKPFV--PNTVNAMINQTIDLSCEVYANPAATIQWV-----IMQGLQII--DSSKFIAKIRPDMDGPLICEAKNYLGSTKETVQLNVLRDPLIHI-DSNYRVPKNSNYSINCRVTSNPPPEFIKWYKLSNMT---------DSSAVLISDDAKLNFILIDRSSTGMYACVTQNIQISTTGKRKPANSEKTMFLTVTYKPKEPQILGNKIISIMKGEKFIIKCSTDRKSPGEPFPTLKW----IDVETKDI-VSDMET--FQVINSESRHNGKYKCLAENEIGKSFSRETALVTVNEAPSIITQHK 1631 R+ S + G YVC R L H SL V ++ F N + + E ++C G P P IS + D+ +R+ I + + A G +C N G + L + +P FV P + +++Q+++ CE +P T++W + +G I D + I ++ G C A+N +G + + L V P + N V + C T NP P I W + + SS +S L +RS G Y+C NI S K A E T ++ P Q N+ + + + C + G P PT+ W + V T D V ++T Q+ ++ G Y C+A G++ + + V V E S I H+ Sbjct: 150 RIVHGRRSKPDEGSYVCVARNYLGEAVSHNASLEVAILRD-----DFRQNPADVMVAAGEPAVLECQPPRGHPEPTISWKKDGVNIDDRDERITIRGGKLMITNARKSDA------------GKYVCVGTNMVGERDSEVAELTVLERPS---FVRRPGSQVVLVDQSVEFRCEARGDPVPTVRWRKDDGELPKGRYEIREDHTLKIRRLTSADVGSYTCVAENMMGKAEASATLTVHVPPAFVVRPRNQVVGVGRTVTFQCEATGNPQPA-IFWQREGSQNLLFSYQPPQPSSRFSVSQTGDLTITDAERSDMGYYSCQALNIAGSVITK---ALLEVTDVVSDRPPPVIRQGPTNQTVPVDG--TVDLNC----MAAGNPTPTILWRKDGVLVSTHDSRVKQLDTGALQIRYAKLGDTGTYTCIASTPSGEASWK--SFVEVQEFGSPIQPHR 572
BLAST of hemicentin-1 isoform X2 vs. Ensembl Medaka
Match: ENSORLT00000042592.1 (roundabout homolog 2 [Source:NCBI gene;Acc:101156842]) HSP 1 Score: 92.4337 bits (228), Expect = 2.438e-18 Identity = 134/585 (22.91%), Postives = 232/585 (39.66%), Query Frame = 3 Query: 942 KIRPDMDGPLICEAKNYLG---STKETVQLNVLRDPLIHIDSNYRVPKNSNYSINCRVTSNPPPEFIKWYKLSNMTDSSAVLISDD------AKLNFILIDRSSTGMYACVTQNIQISTTGKRKPANSEKTMFLTVTYKPKEPQILGNKIISIMKGEKFIIKCSTDRKSPGEPFPTLKWI--DVETKDIVSDMETF--QVINSESRHNGKYKCLAENEIGKSFSRETALVTVN----EAPSIITQHKNRKVFLSYSDLPQSISFTCEFRGQPLYEARWRYGNEKIPPSSQDFKIEDHRNISNERIS-QIFTKLTIDLYSRTFSQQTSLRSSPNGRYNCEADNRHG--IASLDYFLXXXXXXXXXXNIRHRKIAASLNQNVVMI-RCQAESISTMHIKWYKTNEHIVLPFQSKKYSIFEAEVTKYEPERDLFTPGLKVNELTIKDLENDDFSNYSCVASNDQG---------IKKVNFEVVFK---------------SQPDPPYDLRVTDFEWDSVTINWKPGFNGGLTQNYEILVISENFGT------QNVPFYSDKNENTLTITGLYPSTPYEIRIYAVNSIG 2543 + +PD DG +C A+NY+G S ++++ +LRD + V + C+ P W K D + + +SDD KL +S +G++ CV N+ G+R+ SEK L+V KP Q N+++ + + +F +C G+P P L+W DV+ + E F ++ + G + C AEN +GK + +A +T+ EAP + + +++ V ++ +F CE RG+P W+ S+D + + R+S + +LTI +S++ S G Y C+A G +A + IR + V + RCQA + W K +++ + ++S+ E L I++ D Y+CVA++ G ++ ++ V F + P PP VT+ S++++W+PG G + ++ E FG Q V + E T+T L P T Y I AVN+ G Sbjct: 100 RSKPD-DGNYVCVARNYMGEAVSRNASLEVALLRDDFRQNPQDVVVAVGETATFECQPPRGHPEPVTFWRK-----DKTRLDLSDDRITVRGGKLTISNTKKSDSGIFVCVASNM----VGERE---SEKAQ-LSVFEKPSFVQRPVNQVVLVDESVEF--RCQVH----GDPPPVLRWKKEDVDIPRGRYEKEDFLLRIKKASVSDQGTFTCSAENRVGK--TEASAYLTIRARPVEAPQFVVRPRDQIVAQG-----RTATFPCETRGKPQPTVFWQR------EGSKDLLFPNQSAQGDSRVSVSVNGELTI----------SSVQRSDAGYYICQALTVAGSIMAKAQLEVADALKDRPPPIIRQGPSNQTQALGAVSVFRCQASGDPEPTVTWRKNGANLL--GKDPRFSVLEH------------------GSLQIQNSRLSDAGLYTCVATSSSGETSWSAYLDVRGLHCLVFFAFYNVISIYFVFHNSTTLPGPPSKPEVTNVTKSSISLSWEPGPEAGSPVSSYVI---EAFGQSVSNSWQTVADHVKTTE--FTVTDLRPKTVYLFIIRAVNAQG 616 HSP 2 Score: 58.151 bits (139), Expect = 6.560e-8 Identity = 101/458 (22.05%), Postives = 175/458 (38.21%), Query Frame = 3 Query: 1041 LIHIDSNYRVPKNSNYSINCRVTSNPPPEFIKWYKLSNMTDS------SAVLISDDAKLNFILI-----DRSSTGMYACVTQNIQISTTGKRKPANSEKTMFLTVTYKPKEPQILGNKIISIMKGEKFIIKCSTDRKSPGEPFPTLKWIDVETK-DIVSDMETFQ-----VINSESRHNGKYKCLAENEIGKSFSRETALVTVNEAPSIITQHKNRKVFLSYSDLPQSISFTCEFRGQPLYEARWRYGNEKIPPSSQDFKIEDHRNISNERISQIFTKLTIDLYSRTFSQQTSLRSSPNGRYNCEADNRHGIASLDYFLXXXXXXXXXXNIRHRKIAA------SLNQNVVMIR-----CQAESISTMHIKWYK-TNEHIVLPFQSKKYSIFEAEVTKYEPERDLFTPGLKVN-ELTIKDLENDDFSNYSCVASNDQG--IKKVNFEV--VFKSQPDP 2312 ++ S+ V K ++NC+ P P ++WYK ++ S ++ L F+ I + G Y CV +N G+ N+ + L + PQ + ++++ GE +C R G P P W +T+ D+ D T + + N++ +G + C+A N +G+ S E A ++V E PS + + N+ V + +S+ F C+ G P RW+ + IP ++ ED + + + S Q G + C A+NR G +L IR R + A +Q V R C+ + W + ++ ++ P QS + ++ V+ + VN ELTI ++ D Y C A G + K EV K +P P Sbjct: 33 IVEHPSDLIVSKGEPATLNCKAEGRPIPS-VEWYKDGERVETDRDNPRSHRMLLPSGSLFFLRIVHGRRSKPDDGNYVCVARNYM----GEAVSRNASLEVALLRDDFRQNPQ---DVVVAV--GETATFECQPPR---GHPEPVTFWRKDKTRLDLSDDRITVRGGKLTISNTKKSDSGIFVCVASNMVGERES-EKAQLSVFEKPSFVQRPVNQVVLVD-----ESVEFRCQVHGDPPPVLRWKKEDVDIP--RGRYEKED---------------FLLRIKKASVSDQ--------GTFTCSAENRVGKTEASAYL----------TIRARPVEAPQFVVRPRDQIVAQGRTATFPCETRGKPQPTVFWQREGSKDLLFPNQSAQ---GDSRVS------------VSVNGELTISSVQRSDAGYYICQALTVAGSIMAKAQLEVADALKDRPPP 421 HSP 3 Score: 56.225 bits (134), Expect = 2.294e-7 Identity = 65/321 (20.25%), Postives = 124/321 (38.63%), Query Frame = 3 Query: 705 NRGFVMCTAINDAGVLTKNTSLLNIKYKPKIKPFVPNTVN--AMINQTIDLSCEVYANPAATIQWV-----IMQGLQIIDSSKFIAKIRPDM---DGPLICEAKNYLGSTKETVQLNVLRDPLIHIDSNYR-----VPKNSNYSINCRVTSNPPPEFIKWYKLS---------NMTDSSAVLISDDAKLNFILIDRSSTGMYACVTQNIQISTTGKRKPANSEKTMFLTVTYKPKEPQIL--GNKIISIMKGEKFIIKCSTDRKSPGEPFPTLKW-------IDVETKDIVSDMETFQVINSESRHNGKYKCLAENEIGKS 1568 + G +C A N G + L++ KP FV VN +++++++ C+V+ +P ++W I +G + F+ +I+ G C A+N +G T+ + L + P+ R V + + C P P W + + S V +S + +L + RS G Y C + S K + + + K + P I+ G + G + +C ++ G+P PT+ W + + + V + + Q+ NS G Y C+A + G++ Sbjct: 197 DSGIFVCVASNMVGERESEKAQLSVFEKPS---FVQRPVNQVVLVDESVEFRCQVHGDPPPVLRWKKEDVDIPRGR--YEKEDFLLRIKKASVSDQGTFTCSAENRVGKTEASAYLTIRARPVEAPQFVVRPRDQIVAQGRTATFPCETRGKPQPTVF-WQREGSKDLLFPNQSAQGDSRVSVSVNGELTISSVQRSDAGYYICQALTVAGSIMAKAQ-------LEVADALKDRPPPIIRQGPSNQTQALGAVSVFRC----QASGDPEPTVTWRKNGANLLGKDPRFSVLEHGSLQIQNSRLSDAGLYTCVATSSSGET 500
BLAST of hemicentin-1 isoform X2 vs. Ensembl Medaka
Match: ENSORLT00000012625.2 (roundabout homolog 2 [Source:NCBI gene;Acc:101156842]) HSP 1 Score: 91.6633 bits (226), Expect = 3.571e-18 Identity = 135/581 (23.24%), Postives = 234/581 (40.28%), Query Frame = 3 Query: 942 KIRPDMDGPLICEAKNYLG---STKETVQLNVLRDPLIHIDSNYRVPKNSNYSINCRVTSNPPPEFIKWYKLSNMTDSSAVLISDD------AKLNFILIDRSSTGMYACVTQNIQISTTGKRKPANSEKTMFLTVTYKPKEPQILGNKIISIMKGEKFIIKCSTDRKSPGEPFPTLKW----IDVETK--DIVSDMETF--QVINSESRHNGKYKCLAENEIGKSFSRETALVTVN----EAPSIITQHKNRKVFLSYSDLPQSISFTCEFRGQPLYEARWRYGNEKIPPSSQDFKIEDHRNISNERIS-QIFTKLTIDLYSRTFSQQTSLRSSPNGRYNCEADNRHG--IASLDYFLXXXXXXXXXXNIRHRKIAASLNQNVVMI-RCQAESISTMHIKWYKTNEHIVLPFQSKKYSIFEAEVTKYEPERDLFTPGLKVNELTIKDLENDDFSNYSCVASNDQG-------------IKKVNFEVVFKSQ---PDPPYDLRVTDFEWDSVTINWKPGFNGGLTQNYEILVISENFGT------QNVPFYSDKNENTLTITGLYPSTPYEIRIYAVNSIG 2543 + +PD DG +C A+NY+G S ++++ +LRD + V + C+ P W K D + + +SDD KL +S +G++ CV N+ G+R+ SEK L+V KP Q N+++ + + +F +C G+P P L+W +D+ +I + E F ++ + G + C AEN +GK + +A +T+ EAP + + +++ V ++ +F CE RG+P W+ S+D + + R+S + +LTI +S++ S G Y C+A G +A + IR + V + RCQA + W K +++ + ++S+ E L I++ D Y+CVA++ G + ++F VF + P PP VT+ S++++W+PG G + ++ E FG Q V + E T+T L P T Y I AVN+ G Sbjct: 98 RSKPD-DGNYVCVARNYMGEAVSRNASLEVALLRDDFRQNPQDVVVAVGETATFECQPPRGHPEPVTFWRK-----DKTRLDLSDDRITVRGGKLTISNTKKSDSGIFVCVASNM----VGERE---SEKAQ-LSVFEKPSFVQRPVNQVVLVDESVEF--RCQVH----GDPPPVLRWKKEDVDIPRGRYEIRYEKEDFLLRIKKASVSDQGTFTCSAENRVGK--TEASAYLTIRARPVEAPQFVVRPRDQIVAQG-----RTATFPCETRGKPQPTVFWQR------EGSKDLLFPNQSAQGDSRVSVSVNGELTI----------SSVQRSDAGYYICQALTVAGSIMAKAQLEVADALKDRPPPIIRQGPSNQTQALGAVSVFRCQASGDPEPTVTWRKNGANLL--GKDPRFSVLEH------------------GSLQIQNSRLSDAGLYTCVATSSSGETSWSAYLDVRDSMDPIDF--VFHNSTTLPGPPSKPEVTNVTKSSISLSWEPGPEAGSPVSSYVI---EAFGQSVSNSWQTVADHVKTTE--FTVTDLRPKTVYLFIIRAVNAQG 608 HSP 2 Score: 58.5362 bits (140), Expect = 4.543e-8 Identity = 100/458 (21.83%), Postives = 174/458 (37.99%), Query Frame = 3 Query: 1041 LIHIDSNYRVPKNSNYSINCRVTSNPPPEFIKWYKLSNMTDS------SAVLISDDAKLNFILI-----DRSSTGMYACVTQNIQISTTGKRKPANSEKTMFLTVTYKPKEPQILGNKIISIMKGEKFIIKCSTDRKSPGEPFPTLKWIDVETK-DIVSDMETFQ-----VINSESRHNGKYKCLAENEIGKSFSRETALVTVNEAPSIITQHKNRKVFLSYSDLPQSISFTCEFRGQPLYEARWRYGNEKIPPSSQDFKIEDHRNISNERISQIFTKLTIDLYSRTFSQQTSLRSSPNGRYNCEADNRHGIASLDYFLXXXXXXXXXXNIRHRKIAA------SLNQNVVMIR-----CQAESISTMHIKWYK-TNEHIVLPFQSKKYSIFEAEVTKYEPERDLFTPGLKVN-ELTIKDLENDDFSNYSCVASNDQG--IKKVNFEV--VFKSQPDP 2312 ++ S+ V K ++NC+ P P ++WYK ++ S ++ L F+ I + G Y CV +N G+ N+ + L + PQ + ++++ GE +C R G P P W +T+ D+ D T + + N++ +G + C+A N +G+ S E A ++V E PS + + N+ V + +S+ F C+ G P RW+ + IP + + E + + + S Q G + C A+NR G +L IR R + A +Q V R C+ + W + ++ ++ P QS + ++ V+ + VN ELTI ++ D Y C A G + K EV K +P P Sbjct: 31 IVEHPSDLIVSKGEPATLNCKAEGRPIPS-VEWYKDGERVETDRDNPRSHRMLLPSGSLFFLRIVHGRRSKPDDGNYVCVARNYM----GEAVSRNASLEVALLRDDFRQNPQ---DVVVAV--GETATFECQPPR---GHPEPVTFWRKDKTRLDLSDDRITVRGGKLTISNTKKSDSGIFVCVASNMVGERES-EKAQLSVFEKPSFVQRPVNQVVLVD-----ESVEFRCQVHGDPPPVLRWKKEDVDIPRGRYEIRYEKE-------------DFLLRIKKASVSDQ--------GTFTCSAENRVGKTEASAYL----------TIRARPVEAPQFVVRPRDQIVAQGRTATFPCETRGKPQPTVFWQREGSKDLLFPNQSAQ---GDSRVS------------VSVNGELTISSVQRSDAGYYICQALTVAGSIMAKAQLEVADALKDRPPP 423 HSP 3 Score: 55.8398 bits (133), Expect = 3.632e-7 Identity = 66/323 (20.43%), Postives = 125/323 (38.70%), Query Frame = 3 Query: 705 NRGFVMCTAINDAGVLTKNTSLLNIKYKPKIKPFVPNTVN--AMINQTIDLSCEVYANPAATIQWV-----IMQGLQII--DSSKFIAKIRPDM---DGPLICEAKNYLGSTKETVQLNVLRDPLIHIDSNYR-----VPKNSNYSINCRVTSNPPPEFIKWYKLS---------NMTDSSAVLISDDAKLNFILIDRSSTGMYACVTQNIQISTTGKRKPANSEKTMFLTVTYKPKEPQIL--GNKIISIMKGEKFIIKCSTDRKSPGEPFPTLKW-------IDVETKDIVSDMETFQVINSESRHNGKYKCLAENEIGKS 1568 + G +C A N G + L++ KP FV VN +++++++ C+V+ +P ++W I +G I + F+ +I+ G C A+N +G T+ + L + P+ R V + + C P P W + + S V +S + +L + RS G Y C + S K + + + K + P I+ G + G + +C ++ G+P PT+ W + + + V + + Q+ NS G Y C+A + G++ Sbjct: 195 DSGIFVCVASNMVGERESEKAQLSVFEKPS---FVQRPVNQVVLVDESVEFRCQVHGDPPPVLRWKKEDVDIPRGRYEIRYEKEDFLLRIKKASVSDQGTFTCSAENRVGKTEASAYLTIRARPVEAPQFVVRPRDQIVAQGRTATFPCETRGKPQPTVF-WQREGSKDLLFPNQSAQGDSRVSVSVNGELTISSVQRSDAGYYICQALTVAGSIMAKAQ-------LEVADALKDRPPPIIRQGPSNQTQALGAVSVFRC----QASGDPEPTVTWRKNGANLLGKDPRFSVLEHGSLQIQNSRLSDAGLYTCVATSSSGET 502
BLAST of hemicentin-1 isoform X2 vs. Ensembl Medaka
Match: igsf9bb (protein turtle homolog B-like [Source:NCBI gene;Acc:101174449]) HSP 1 Score: 91.2781 bits (225), Expect = 4.550e-18 Identity = 119/522 (22.80%), Postives = 211/522 (40.42%), Query Frame = 3 Query: 159 PNNATVNSKENLTLECVVDQQNIVYSWEYKPFHIKSNIMSKVLGFCY---FEKPCVVPDSESQITISHESRLTIHNISSDNSGYYVCRVTLLTT---SEHIISLAVVTVKTPPKSISFHFNKSINVF---QEQEFIAIQCSVSGGIPPPKISMYIVKDNAIKRLKIISSNFPNSTIAEVSAISLWRPHYLENRGFVMCTAINDAGVLTKNTSLLNIKYKPKIKPFV---PNTVNAMINQTIDLSCEVYANPA-ATIQWVIMQ-------GLQ-----IIDSSKFIAKIRPDMDGPLICEAKNYLGSTKETVQLNVLRDP--LIHIDSNYRVPKNSNYSINCRVTSNPPPEFIKWYK---LSNMTDSSAVLISDDAKLNFILIDRSSTGMYACVTQNIQISTTGKRKPANSEKTMFLTVTYKPKEPQILGNKIISIMKGEKFIIKCSTDRKSPGEPFPTLKWIDV----ETKDIVSDMETFQVINSESRHNGKYKCLAENEIGKSFSRETALVTVNEAPSIIT 1622 P T + E++ L C N+ + +P+ ++ + F F P V P+ + ++ +S L I N+ SD+ G+Y C+V +L + H S +TV PP F + + +E I + C G PK S+ +++ ++ ++SS + ++ +S+ R ++RG MC A + G T LL + PF+ P + I+Q +C+ A P T W Q L+ +ID S IA+++P+ G C N LG ++ P ++++ S V I C V +NPP +KW K + DD + + S G Y+C+ N + + G PA L + PK + G + + G + +I C + G+PFP + W V +K V + Q+ + +G+++C+A N + S + T + + +P T Sbjct: 30 PQFVTARAGESVILGC-----NVPHPLNGQPYVVEWFKYGMPIPFFINFRFYPPHVDPEYAGRASLHGKSSLRIDNVRSDDHGWYECKVLMLQQQYDTFHNGSWVHLTVNAPPT-----FTDTPPQYVEAKEGGSITLTCMAFGN---PKPSVSWLREGSL----MVSSAKYKLSDGSLTVLSITR----QDRGAYMCRAFSLQGEAIHTTRLLV-----QGPPFIISPPENITVNISQDAFFTCQAEAYPRNLTYTWFWEQDNVFFKNDLKRRVSILIDGSLIIAQVKPEDAGKYTCVPSNSLGQPPSASAYLTVQYPARVVNMPSVIYVAIGLPGFIRCPVDANPPVTLVKWKKDGLFLRIDKFPGWSQMDDGSIRVAEVTEDSLGTYSCMPYN-ALGSMGWSPPAP------LVLKDPPKFSVVPGGEYRQEV-GRELVIPCEAE----GDPFPNITWRKVGKPSRSKHNVLPRGSLQLKSLTKEDHGEWECVATN-VATSITASTHVQVIGTSPHAPT 512 HSP 2 Score: 53.9138 bits (128), Expect = 1.236e-6 Identity = 39/140 (27.86%), Postives = 61/140 (43.57%), Query Frame = 3 Query: 2181 LKVNELTIKDLENDDFSNYSCVASN-DQGIKKVNFEVVFKSQPDPPYDLR-VTDFEWDSVTINWKPGFNGGLTQNYEILVISENFGTQN-----VPFYSDKNENTLTITGLYPSTPYEIRIYAVNSIGRSLNSETVKCVT 2579 L L +K L +D + CVA+N I V + P P ++ V W +V+ W+ G++GG Q + + + E G + VP +N ++GL P T Y+ + A N +G S SE V T Sbjct: 466 LPRGSLQLKSLTKEDHGEWECVATNVATSITASTHVQVIGTSPHAPTNVHAVASSTWANVS--WEAGYSGGFQQTFSVWIKRERLGPHDWLSTAVP----GGQNWKLVSGLEPETTYQFSVLAQNKLGTSPFSEVVTVNT 599
BLAST of hemicentin-1 isoform X2 vs. Planmine SMEST
Match: SMESG000003113.1 (SMESG000003113.1) HSP 1 Score: 2290 bits (5933), Expect = 0.000e+0 Identity = 1177/1183 (99.49%), Postives = 1178/1183 (99.58%), Query Frame = 3 Query: 75 MEYFKTFILITLFGNLMDRSYTLNFLITPNNATVNSKENLTLECVVDQQNIVYSWEYKPFHIKSNIMSKVLGFCYFEKPCVVPDSESQITISHESRLTIHNISSDNSGYYVCRVTLLTTSEHIISLAVVTVKTPPKSISFHFNKSINVFQEQEFIAIQCSVSGGIPPPKISMYIVKDNAIKRLKIISSNFPNSTIAEVSAISLWRPHYLENRGFVMCTAINDAGVLTKNTSLLNIKYKPKIKPFVPNTVNAMINQTIDLSCEVYANPAATIQWVIMQGLQIIDSSKFIAKIRPDMDGPLICEAKNYLGSTKETVQLNVLRDPLIHIDSNYRVPKNSNYSINCRVTSNPPPEFIKWYKLSNMTDSSAVLISDDAKLNFILIDRSSTGMYACVTQNIQISTTGKRKPANSEKTMFLTVTYKPKEPQILGNKIISIMKGEKFIIKCSTDRKSPGEPFPTLKWIDVETKDIVSDMETFQVINSESRHNGKYKCLAENEIGKSFSRETALVTVNEAPSIITQHKNRKVFLSYSDLPQSISFTCEFRGQPLYEARWRYGNEKIPPSSQDFKIEDHRNISNERISQIFTKLTIDLYSRTFSQQTSLRSSPNGRYNCEADNRHGIASLDYFLXXXXXXXXXXNIRHRKIAASLNQNVVMIRCQAESISTMHIKWYKTNEHIVLPFQSKKYSIFEAEVTKYEPERDLFTPGLKVNELTIKDLENDDFSNYSCVASNDQGIKKVNFEVVFKSQPDPPYDLRVTDFEWDSVTINWKPGFNGGLTQNYEILVISENFGTQNVPFYSDKNENTLTITGLYPSTPYEIRIYAVNSIGRSLNSETVKCVTKRIRKFDKIQAKILSDQPKIAVIIQEPDVCANLEYTRDNGHQWFSILHCIRFNASHINETVLLDIIRVASILDLQSGLIHLRLTFCLISRPSVCSPHRILENPKNENLATQXXXXXXXXXXXXXXXXXXXXXXXXXXRFRYHCVSCNQYFCHNYCCFPRFYGATNKPIRHYNNNRIPYDGKPLSCSRVSCQDILDENDINTGSTSNYCSSLIGSSTPHIMNKKCPQNSSNDVYSSFICPHHEFRSHIPVLYEGSSFLQPTVLSWSQKIXXXXXXXXXXXXXXXXXXXXXRNLPQNSVHYRKKQDGISNSNVVNHKSYAQTEGIIKLPDVTSEAIHFVKPDYNEKLMEA 3623 MEYFKTFILITLFGNLMDRSYTLNFLITPNNATVNSKENLTLECVVDQQNIVYSWEYKPFHIKSN MSKVLGFCYFEKPCVVPDSESQITISHESRLTIHNISSDNSGYYVCRVTLLTTSEHIISLAVVTVKTPPKSISFHFNKSINVFQEQEFIAIQCSVSGGIPPPKISMYIVKDNAIKRLKIISSNFPNSTIAEVSAISLWRPHYLENRGFVMCTAINDAGVLTKNTSLLNIKYKPKIKPFVPNTVNAMINQTIDLSCEVY+NPAATIQWVIMQGLQIIDSSKFIAKIRPDMDGPLICEAKNYLGSTKETVQLNVLRDPLIHIDSNYRVPKNSNYSINCRVTSNPPPEFIKWYKLSNMTDSSAVLISDDAKLNFILIDRSSTGMYACVTQNIQISTTGKRKPANSEKTMFLTVTYKPKEPQILGNKIISIMKGEKFIIKCSTDRKSPGEPFPTLKWIDVETKDIVSD ETFQVINSESRHNGKYKCLAENEIGKSFSRETALVTVNEAPSIITQHKNRKVFLSYSDLPQSISFTCEFRGQPLYEARWRYGNEKIPPSSQDFKIEDHRNISNERISQIFTKLTIDLYS TFSQQTSLRSSPNGRYNCEADNRHGIASLDYFLIIKYPPIIKYNIRHRKIAASLNQNV MIRCQAESISTMHIKWYKTNEHIVLPFQSKKYSIFEAEVTKYEPERDLFTPGLKVNELTIKDLENDDFSNYSCVASNDQGIKKVNFEVVFKSQPDPPYDLRVTDFEWDSVTINWKPGFNGGLTQNYEILVISENFGTQNVPFYSDKNENTLTITGLYPSTPYEIRIYAVNSIGRSLNSETVKCVTKRIRKFDKIQAKILSDQPKIAVIIQEPDVCANLEYTRDNGHQWFSILHCIRFNASHINETVLLDIIRVASILDLQSGLIHLRLTFCLISRPSVCSPHRILENPKNENLATQTVILVITVICFLLIIILIALFIVCCIRFRYHCVSCNQYFCHNYCCFPRFYGATNKPIRHYNNNRIPYDGKPLSCSRVSCQDILDENDINTGSTSNYCSSLIGSSTPHIMNKKCPQNSSNDVYSSFICPHHEFRSHIPVLYEGSSFLQPTVLSWSQKISPPSCEASSSHSHSSSTGSSSRNLPQN VHYRKKQDGISNSNVVNHKSYAQTEGIIKLPDVTSEAIHFVKPDYNEKLMEA Sbjct: 1 MEYFKTFILITLFGNLMDRSYTLNFLITPNNATVNSKENLTLECVVDQQNIVYSWEYKPFHIKSNSMSKVLGFCYFEKPCVVPDSESQITISHESRLTIHNISSDNSGYYVCRVTLLTTSEHIISLAVVTVKTPPKSISFHFNKSINVFQEQEFIAIQCSVSGGIPPPKISMYIVKDNAIKRLKIISSNFPNSTIAEVSAISLWRPHYLENRGFVMCTAINDAGVLTKNTSLLNIKYKPKIKPFVPNTVNAMINQTIDLSCEVYSNPAATIQWVIMQGLQIIDSSKFIAKIRPDMDGPLICEAKNYLGSTKETVQLNVLRDPLIHIDSNYRVPKNSNYSINCRVTSNPPPEFIKWYKLSNMTDSSAVLISDDAKLNFILIDRSSTGMYACVTQNIQISTTGKRKPANSEKTMFLTVTYKPKEPQILGNKIISIMKGEKFIIKCSTDRKSPGEPFPTLKWIDVETKDIVSDTETFQVINSESRHNGKYKCLAENEIGKSFSRETALVTVNEAPSIITQHKNRKVFLSYSDLPQSISFTCEFRGQPLYEARWRYGNEKIPPSSQDFKIEDHRNISNERISQIFTKLTIDLYSPTFSQQTSLRSSPNGRYNCEADNRHGIASLDYFLIIKYPPIIKYNIRHRKIAASLNQNVAMIRCQAESISTMHIKWYKTNEHIVLPFQSKKYSIFEAEVTKYEPERDLFTPGLKVNELTIKDLENDDFSNYSCVASNDQGIKKVNFEVVFKSQPDPPYDLRVTDFEWDSVTINWKPGFNGGLTQNYEILVISENFGTQNVPFYSDKNENTLTITGLYPSTPYEIRIYAVNSIGRSLNSETVKCVTKRIRKFDKIQAKILSDQPKIAVIIQEPDVCANLEYTRDNGHQWFSILHCIRFNASHINETVLLDIIRVASILDLQSGLIHLRLTFCLISRPSVCSPHRILENPKNENLATQTVILVITVICFLLIIILIALFIVCCIRFRYHCVSCNQYFCHNYCCFPRFYGATNKPIRHYNNNRIPYDGKPLSCSRVSCQDILDENDINTGSTSNYCSSLIGSSTPHIMNKKCPQNSSNDVYSSFICPHHEFRSHIPVLYEGSSFLQPTVLSWSQKISPPSCEASSSHSHSSSTGSSSRNLPQNPVHYRKKQDGISNSNVVNHKSYAQTEGIIKLPDVTSEAIHFVKPDYNEKLMEA 1183
BLAST of hemicentin-1 isoform X2 vs. Planmine SMEST
Match: SMESG000003113.1 (SMESG000003113.1) HSP 1 Score: 2256.48 bits (5846), Expect = 0.000e+0 Identity = 1161/1167 (99.49%), Postives = 1162/1167 (99.57%), Query Frame = 3 Query: 123 MDRSYTLNFLITPNNATVNSKENLTLECVVDQQNIVYSWEYKPFHIKSNIMSKVLGFCYFEKPCVVPDSESQITISHESRLTIHNISSDNSGYYVCRVTLLTTSEHIISLAVVTVKTPPKSISFHFNKSINVFQEQEFIAIQCSVSGGIPPPKISMYIVKDNAIKRLKIISSNFPNSTIAEVSAISLWRPHYLENRGFVMCTAINDAGVLTKNTSLLNIKYKPKIKPFVPNTVNAMINQTIDLSCEVYANPAATIQWVIMQGLQIIDSSKFIAKIRPDMDGPLICEAKNYLGSTKETVQLNVLRDPLIHIDSNYRVPKNSNYSINCRVTSNPPPEFIKWYKLSNMTDSSAVLISDDAKLNFILIDRSSTGMYACVTQNIQISTTGKRKPANSEKTMFLTVTYKPKEPQILGNKIISIMKGEKFIIKCSTDRKSPGEPFPTLKWIDVETKDIVSDMETFQVINSESRHNGKYKCLAENEIGKSFSRETALVTVNEAPSIITQHKNRKVFLSYSDLPQSISFTCEFRGQPLYEARWRYGNEKIPPSSQDFKIEDHRNISNERISQIFTKLTIDLYSRTFSQQTSLRSSPNGRYNCEADNRHGIASLDYFLXXXXXXXXXXNIRHRKIAASLNQNVVMIRCQAESISTMHIKWYKTNEHIVLPFQSKKYSIFEAEVTKYEPERDLFTPGLKVNELTIKDLENDDFSNYSCVASNDQGIKKVNFEVVFKSQPDPPYDLRVTDFEWDSVTINWKPGFNGGLTQNYEILVISENFGTQNVPFYSDKNENTLTITGLYPSTPYEIRIYAVNSIGRSLNSETVKCVTKRIRKFDKIQAKILSDQPKIAVIIQEPDVCANLEYTRDNGHQWFSILHCIRFNASHINETVLLDIIRVASILDLQSGLIHLRLTFCLISRPSVCSPHRILENPKNENLATQXXXXXXXXXXXXXXXXXXXXXXXXXXRFRYHCVSCNQYFCHNYCCFPRFYGATNKPIRHYNNNRIPYDGKPLSCSRVSCQDILDENDINTGSTSNYCSSLIGSSTPHIMNKKCPQNSSNDVYSSFICPHHEFRSHIPVLYEGSSFLQPTVLSWSQKIXXXXXXXXXXXXXXXXXXXXXRNLPQNSVHYRKKQDGISNSNVVNHKSYAQTEGIIKLPDVTSEAIHFVKPDYNEKLMEA 3623 MDRSYTLNFLITPNNATVNSKENLTLECVVDQQNIVYSWEYKPFHIKSN MSKVLGFCYFEKPCVVPDSESQITISHESRLTIHNISSDNSGYYVCRVTLLTTSEHIISLAVVTVKTPPKSISFHFNKSINVFQEQEFIAIQCSVSGGIPPPKISMYIVKDNAIKRLKIISSNFPNSTIAEVSAISLWRPHYLENRGFVMCTAINDAGVLTKNTSLLNIKYKPKIKPFVPNTVNAMINQTIDLSCEVY+NPAATIQWVIMQGLQIIDSSKFIAKIRPDMDGPLICEAKNYLGSTKETVQLNVLRDPLIHIDSNYRVPKNSNYSINCRVTSNPPPEFIKWYKLSNMTDSSAVLISDDAKLNFILIDRSSTGMYACVTQNIQISTTGKRKPANSEKTMFLTVTYKPKEPQILGNKIISIMKGEKFIIKCSTDRKSPGEPFPTLKWIDVETKDIVSD ETFQVINSESRHNGKYKCLAENEIGKSFSRETALVTVNEAPSIITQHKNRKVFLSYSDLPQSISFTCEFRGQPLYEARWRYGNEKIPPSSQDFKIEDHRNISNERISQIFTKLTIDLYS TFSQQTSLRSSPNGRYNCEADNRHGIASLDYFLIIKYPPIIKYNIRHRKIAASLNQNV MIRCQAESISTMHIKWYKTNEHIVLPFQSKKYSIFEAEVTKYEPERDLFTPGLKVNELTIKDLENDDFSNYSCVASNDQGIKKVNFEVVFKSQPDPPYDLRVTDFEWDSVTINWKPGFNGGLTQNYEILVISENFGTQNVPFYSDKNENTLTITGLYPSTPYEIRIYAVNSIGRSLNSETVKCVTKRIRKFDKIQAKILSDQPKIAVIIQEPDVCANLEYTRDNGHQWFSILHCIRFNASHINETVLLDIIRVASILDLQSGLIHLRLTFCLISRPSVCSPHRILENPKNENLATQTVILVITVICFLLIIILIALFIVCCIRFRYHCVSCNQYFCHNYCCFPRFYGATNKPIRHYNNNRIPYDGKPLSCSRVSCQDILDENDINTGSTSNYCSSLIGSSTPHIMNKKCPQNSSNDVYSSFICPHHEFRSHIPVLYEGSSFLQPTVLSWSQKISPPSCEASSSHSHSSSTGSSSRNLPQN VHYRKKQDGISNSNVVNHKSYAQTEGIIKLPDVTSEAIHFVKPDYNEKLMEA Sbjct: 1 MDRSYTLNFLITPNNATVNSKENLTLECVVDQQNIVYSWEYKPFHIKSNSMSKVLGFCYFEKPCVVPDSESQITISHESRLTIHNISSDNSGYYVCRVTLLTTSEHIISLAVVTVKTPPKSISFHFNKSINVFQEQEFIAIQCSVSGGIPPPKISMYIVKDNAIKRLKIISSNFPNSTIAEVSAISLWRPHYLENRGFVMCTAINDAGVLTKNTSLLNIKYKPKIKPFVPNTVNAMINQTIDLSCEVYSNPAATIQWVIMQGLQIIDSSKFIAKIRPDMDGPLICEAKNYLGSTKETVQLNVLRDPLIHIDSNYRVPKNSNYSINCRVTSNPPPEFIKWYKLSNMTDSSAVLISDDAKLNFILIDRSSTGMYACVTQNIQISTTGKRKPANSEKTMFLTVTYKPKEPQILGNKIISIMKGEKFIIKCSTDRKSPGEPFPTLKWIDVETKDIVSDTETFQVINSESRHNGKYKCLAENEIGKSFSRETALVTVNEAPSIITQHKNRKVFLSYSDLPQSISFTCEFRGQPLYEARWRYGNEKIPPSSQDFKIEDHRNISNERISQIFTKLTIDLYSPTFSQQTSLRSSPNGRYNCEADNRHGIASLDYFLIIKYPPIIKYNIRHRKIAASLNQNVAMIRCQAESISTMHIKWYKTNEHIVLPFQSKKYSIFEAEVTKYEPERDLFTPGLKVNELTIKDLENDDFSNYSCVASNDQGIKKVNFEVVFKSQPDPPYDLRVTDFEWDSVTINWKPGFNGGLTQNYEILVISENFGTQNVPFYSDKNENTLTITGLYPSTPYEIRIYAVNSIGRSLNSETVKCVTKRIRKFDKIQAKILSDQPKIAVIIQEPDVCANLEYTRDNGHQWFSILHCIRFNASHINETVLLDIIRVASILDLQSGLIHLRLTFCLISRPSVCSPHRILENPKNENLATQTVILVITVICFLLIIILIALFIVCCIRFRYHCVSCNQYFCHNYCCFPRFYGATNKPIRHYNNNRIPYDGKPLSCSRVSCQDILDENDINTGSTSNYCSSLIGSSTPHIMNKKCPQNSSNDVYSSFICPHHEFRSHIPVLYEGSSFLQPTVLSWSQKISPPSCEASSSHSHSSSTGSSSRNLPQNPVHYRKKQDGISNSNVVNHKSYAQTEGIIKLPDVTSEAIHFVKPDYNEKLMEA 1167
BLAST of hemicentin-1 isoform X2 vs. Planmine SMEST
Match: SMESG000015102.1 (SMESG000015102.1) HSP 1 Score: 185.652 bits (470), Expect = 2.431e-47 Identity = 209/861 (24.27%), Postives = 359/861 (41.70%), Query Frame = 3 Query: 363 LTIHNISSDNSGYYVCRVTLLTTSEHIISLAVVTVKTPPKSISFHFNKSINVFQEQEFIAIQCSVSGGIPPPKISMYIVKD---NAIKRLKIISSNFPNSTI--AEVSAISLWRPHYLENRGFVMCTAINDAGVLTKNTSLLNIKYKPKIKPFVPNTVNAMINQTIDLSCEVYANPAATIQWVIMQGLQIIDSSKFIAK-IRPDMDGPLICEAKNYLGSTKETVQLNVLRDPLIHIDSNYRVPKNSNYSINCRVTSNPPPEFIKWYKLSNMTDSSAVLISDDAKLNFILIDRSSTGMYACVTQNIQIS--TTGKRKPANSEKTMFLTVTYKPKEPQILGNKIISIMKGEKFIIKCSTDRKSPGEPFPTLKWIDVETKDIVSDMETFQVINSESRHNGKYKCLAENEIGKSFSRETALVTVNEAPSIITQHKNRKVFLSYSD----LPQSISFTCEFRGQPLYEARWRYGNEKIPPSSQDFKIE-DHRNISNERISQIFTKLTIDLYSRTFSQQTSLRSSPNGRYNCEADNRHGIASLDYFLXXXXXXXXXXN--IRHRKIAA-SLNQNVVMIRCQAESISTMHIKWYKTNEHIVLPFQSKKYSIFEAEVTKYE-PERDLFTPGLKVNELTIKDLENDDFSNYSCVASNDQGIKKVNFEVVFKSQPDPPYDLRVTDFEWDSVTINWKPGFNGGLTQNYEILVISENFGTQNVPFYSDKNENTLTITGLYPSTPYEIRIYAVNSIGRSLNSETVKCVTKRIRKFDKIQAKILSDQPKIAVI-----IQEPDVC---ANLEYTRDNGHQWFSILHCIRFNASHINETVLLDIIRVASILDLQSGLIHLRLTFCLISRPSVCSPH 2870 +TI N +S NSG Y C L+ ++ V++ TPP + N + E ++C+ GG PPP + ++ KD N I + + I + +STI ++ + W P E+ + C A N ++ N +++ Y P I F T + I++ C+ + AAT +W+ +G D S I K +R G C KN G++ ++ + VL +P I I + + ++ C V P + W + + L+ + N I+ + Y +++Q S TT KRK + + V Y P++P I +M G + C ++K PG P P W T + + E H+G Y C N +G S AL V P + + S+SD + QS + C F+ QP W +E + +S + ++++ +N I+ I + + ++ + N +Y C A+NR+G DYF+ + Y P I N I+ KI+ S ++ V + C + + I W + + F K I E + KY ER+L K + L IK+ ++DD+ Y C A+N +G +F + + PDP ++L + + S+T+ W GF+GG Q +S Q P + +T+ L P Y + I + N IG S +++ T + D+ Q ++ K+ + C N++ +D W + CI+ + IR+ + D R+ CLI+ P VCS + Sbjct: 150 ITIRNANSKNSGLYKC--VHLSYPKYERHHYDVSILTPPGKPQIYTNAGLT---ENVTAHLKCTSEGGYPPPTLK-WVWKDFSNNLISKERRIKTTITSSTIKYGLITLSTTWLPKSNEDGDSLNCVAENSLATVSSNWVYISVNYAPIIYEFPQKTYYGLEGDEINIECKATSKSAATYKWISDKGTVYSDGSYLIIKPLRTSDKGSYSCVVKNSYGTSSASLDIKVLSEPKISIPEAVVINEWETLNLTCDVI--PKTSNVTWLLKDKVLSNLKNLVHNVVGHNSFEIECRA---YVFTKRHLQYSIITTSKRK-------VKVIVHYIPQKPTISAIPAGKLMTGSSVTLTCIPNKKKPGLPNPDYSWKKRHTDWYTNGTNFLSISTLEFEHSGIYCCKLFNSLGSSDESCYAL-NVEGKPVM-----KKSALSSFSDVSARIGQSFNIVCLFQAQPHPIINWYNNDELVENNSNSTRFNMENKSANNSLITSIL-----------YVNEPNV--NINEKYRCTAENRYGTIFKDYFVKVIYSPRILSNVFIKAAKISGFSSDKQSVNLNCTVTASPLIRILWIRKLHN----FNEK---IIENDTDKYLIKERNLLGIIGKESLLFIKNFQSDDYGAYICYANNSEGYIANDFIIRKFAIPDPAHNLVIESRTYCSLTLKWNAGFDGGYQQ---FFTVSYTTTMQKHPLQVRTIHSNITLINLLPEVLYIVNISSSNQIGTSTLVRSIETRTAEL-PIDRDQIFFVNKDEKVIEFSLPLNMSSSIFCLTIENMDTQKDLVGDWALVGKCIKNSIRK---------IRIENPND------RFRVKICLINLPDVCSTY 947
BLAST of hemicentin-1 isoform X2 vs. Planmine SMEST
Match: SMESG000015102.1 (SMESG000015102.1) HSP 1 Score: 185.267 bits (469), Expect = 2.702e-47 Identity = 208/861 (24.16%), Postives = 360/861 (41.81%), Query Frame = 3 Query: 363 LTIHNISSDNSGYYVCRVTLLTTSEHIISLAVVTVKTPPKSISFHFNKSINVFQEQEFIAIQCSVSGGIPPPKISMYIVKD---NAIKRLKIISSNFPNSTI--AEVSAISLWRPHYLENRGFVMCTAINDAGVLTKNTSLLNIKYKPKIKPFVPNTVNAMINQTIDLSCEVYANPAATIQWVIMQGLQIIDSSKFIAK-IRPDMDGPLICEAKNYLGSTKETVQLNVLRDPLIHIDSNYRVPKNSNYSINCRVTSNPPPEFIKWYKLSNMTDSSAVLISDDAKLNFILIDRSSTGMYACVTQNIQIS--TTGKRKPANSEKTMFLTVTYKPKEPQILGNKIISIMKGEKFIIKCSTDRKSPGEPFPTLKWIDVETKDIVSDMETFQVINSESRHNGKYKCLAENEIGKSFSRETALVTVNEAPSIITQHKNRKVFLSYSD----LPQSISFTCEFRGQPLYEARWRYGNEKIPPSSQDFKIE-DHRNISNERISQIFTKLTIDLYSRTFSQQTSLRSSPNGRYNCEADNRHGIASLDYFLXXXXXXXXXXN--IRHRKIAA-SLNQNVVMIRCQAESISTMHIKWYKTNEHIVLPFQSKKYSIFEAEVTKYE-PERDLFTPGLKVNELTIKDLENDDFSNYSCVASNDQGIKKVNFEVVFKSQPDPPYDLRVTDFEWDSVTINWKPGFNGGLTQNYEILVISENFGTQNVPFYSDKNENTLTITGLYPSTPYEIRIYAVNSIGRSLNSETVKCVTKRIRKFDKIQAKILSDQPKIAVIIQEPDVCA--------NLEYTRDNGHQWFSILHCIRFNASHINETVLLDIIRVASILDLQSGLIHLRLTFCLISRPSVCSPH 2870 +TI N +S NSG Y C L+ ++ V++ TPP + N + E ++C+ GG PPP + ++ KD N I + + I + +STI ++ + W P E+ + C A N ++ N +++ Y P I F T + I++ C+ + AAT +W+ +G D S I K +R G C KN G++ ++ + VL +P I I + + ++ C V P + W + + L+ + N I+ + Y +++Q S TT KRK + + V Y P++P I +M G + C ++K PG P P W T + + E H+G Y C N +G S AL V P + + S+SD + QS + C F+ QP W +E + +S + ++++ +N I+ I + + ++ + N +Y C A+NR+G DYF+ + Y P I N I+ KI+ S ++ V + C + + I W + + F K I E + KY ER+L K + L IK+ ++DD+ Y C A+N +G +F + + PDP ++L + + S+T+ W GF+GG Q +S Q P + +T+ L P Y + I + N IG S +++ T + D+ Q ++ K+ ++ + N++ +D W + CI+ + IR+ + D R+ CLI+ P VCS + Sbjct: 101 ITIRNANSKNSGLYKC--VHLSYPKYERHHYDVSILTPPGKPQIYTNAGLT---ENVTAHLKCTSEGGYPPPTLK-WVWKDFSNNLISKERRIKTTITSSTIKYGLITLSTTWLPKSNEDGDSLNCVAENSLATVSSNWVYISVNYAPIIYEFPQKTYYGLEGDEINIECKATSKSAATYKWISDKGTVYSDGSYLIIKPLRTSDKGSYSCVVKNSYGTSSASLDIKVLSEPKISIPEAVVINEWETLNLTCDVI--PKTSNVTWLLKDKVLSNLKNLVHNVVGHNSFEIECRA---YVFTKRHLQYSIITTSKRK-------VKVIVHYIPQKPTISAIPAGKLMTGSSVTLTCIPNKKKPGLPNPDYSWKKRHTDWYTNGTNFLSISTLEFEHSGIYCCKLFNSLGSSDESCYAL-NVEGKPVM-----KKSALSSFSDVSARIGQSFNIVCLFQAQPHPIINWYNNDELVENNSNSTRFNMENKSANNSLITSIL-----------YVNEPNV--NINEKYRCTAENRYGTIFKDYFVKVIYSPRILSNVFIKAAKISGFSSDKQSVNLNCTVTASPLIRILWIRKLHN----FNEK---IIENDTDKYLIKERNLLGIIGKESLLFIKNFQSDDYGAYICYANNSEGYIANDFIIRKFAIPDPAHNLVIESRTYCSLTLKWNAGFDGGYQQ---FFTVSYTTTMQKHPLQVRTIHSNITLINLLPEVLYIVNISSSNQIGTSTLVRSIETRTAEL-PIDRDQIFFVNKDEKVIEFSLPLNMSSSIFCLTIENMDTQKDLVGDWALVGKCIKNSIRK---------IRIENPND------RFRVKICLINLPDVCSTY 898
BLAST of hemicentin-1 isoform X2 vs. Planmine SMEST
Match: SMESG000015102.1 (SMESG000015102.1) HSP 1 Score: 184.882 bits (468), Expect = 4.064e-47 Identity = 208/861 (24.16%), Postives = 360/861 (41.81%), Query Frame = 3 Query: 363 LTIHNISSDNSGYYVCRVTLLTTSEHIISLAVVTVKTPPKSISFHFNKSINVFQEQEFIAIQCSVSGGIPPPKISMYIVKD---NAIKRLKIISSNFPNSTI--AEVSAISLWRPHYLENRGFVMCTAINDAGVLTKNTSLLNIKYKPKIKPFVPNTVNAMINQTIDLSCEVYANPAATIQWVIMQGLQIIDSSKFIAK-IRPDMDGPLICEAKNYLGSTKETVQLNVLRDPLIHIDSNYRVPKNSNYSINCRVTSNPPPEFIKWYKLSNMTDSSAVLISDDAKLNFILIDRSSTGMYACVTQNIQIS--TTGKRKPANSEKTMFLTVTYKPKEPQILGNKIISIMKGEKFIIKCSTDRKSPGEPFPTLKWIDVETKDIVSDMETFQVINSESRHNGKYKCLAENEIGKSFSRETALVTVNEAPSIITQHKNRKVFLSYSD----LPQSISFTCEFRGQPLYEARWRYGNEKIPPSSQDFKIE-DHRNISNERISQIFTKLTIDLYSRTFSQQTSLRSSPNGRYNCEADNRHGIASLDYFLXXXXXXXXXXN--IRHRKIAA-SLNQNVVMIRCQAESISTMHIKWYKTNEHIVLPFQSKKYSIFEAEVTKYE-PERDLFTPGLKVNELTIKDLENDDFSNYSCVASNDQGIKKVNFEVVFKSQPDPPYDLRVTDFEWDSVTINWKPGFNGGLTQNYEILVISENFGTQNVPFYSDKNENTLTITGLYPSTPYEIRIYAVNSIGRSLNSETVKCVTKRIRKFDKIQAKILSDQPKIAVIIQEPDVCA--------NLEYTRDNGHQWFSILHCIRFNASHINETVLLDIIRVASILDLQSGLIHLRLTFCLISRPSVCSPH 2870 +TI N +S NSG Y C L+ ++ V++ TPP + N + E ++C+ GG PPP + ++ KD N I + + I + +STI ++ + W P E+ + C A N ++ N +++ Y P I F T + I++ C+ + AAT +W+ +G D S I K +R G C KN G++ ++ + VL +P I I + + ++ C V P + W + + L+ + N I+ + Y +++Q S TT KRK + + V Y P++P I +M G + C ++K PG P P W T + + E H+G Y C N +G S AL V P + + S+SD + QS + C F+ QP W +E + +S + ++++ +N I+ I + + ++ + N +Y C A+NR+G DYF+ + Y P I N I+ KI+ S ++ V + C + + I W + + F K I E + KY ER+L K + L IK+ ++DD+ Y C A+N +G +F + + PDP ++L + + S+T+ W GF+GG Q +S Q P + +T+ L P Y + I + N IG S +++ T + D+ Q ++ K+ ++ + N++ +D W + CI+ + IR+ + D R+ CLI+ P VCS + Sbjct: 101 ITIRNANSKNSGLYKC--VHLSYPKYERHHYDVSILTPPGKPQIYTNAGLT---ENVTAHLKCTSEGGYPPPTLK-WVWKDFSNNLISKERRIKTTITSSTIKYGLITLSTTWLPKSNEDGDSLNCVAENSLATVSSNWVYISVNYAPIIYEFPQKTYYGLEGDEINIECKATSKSAATYKWISDKGTVYSDGSYLIIKPLRTSDKGSYSCVVKNSYGTSSASLDIKVLSEPKISIPEAVVINEWETLNLTCDVI--PKTSNVTWLLKDKVLSNLKNLVHNVVGHNSFEIECRA---YVFTKRHLQYSIITTSKRK-------VKVIVHYIPQKPTISAIPAGKLMTGSSVTLTCIPNKKKPGLPNPDYSWKKRHTDWYTNGTNFLSISTLEFEHSGIYCCKLFNSLGSSDESCYAL-NVEGKPVM-----KKSALSSFSDVSARIGQSFNIVCLFQAQPHPIINWYNNDELVENNSNSTRFNMENKSANNSLITSIL-----------YVNEPNV--NINEKYRCTAENRYGTIFKDYFVKVIYSPRILSNVFIKAAKISGFSSDKQSVNLNCTVTASPLIRILWIRKLHN----FNEK---IIENDTDKYLIKERNLLGIIGKESLLFIKNFQSDDYGAYICYANNSEGYIANDFIIRKFAIPDPAHNLVIESRTYCSLTLKWNAGFDGGYQQ---FFTVSYTTTMQKHPLQVRTIHSNITLINLLPEVLYIVNISSSNQIGTSTLVRSIETRTAEL-PIDRDQIFFVNKDEKVIEFSLPLNMSSSIFCLTIENMDTQKDLVGDWALVGKCIKNSIRK---------IRIENPND------RFRVKICLINLPDVCSTY 898 The following BLAST results are available for this feature:
BLAST of hemicentin-1 isoform X2 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of hemicentin-1 isoform X2 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of hemicentin-1 isoform X2 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of hemicentin-1 isoform X2 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of hemicentin-1 isoform X2 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of hemicentin-1 isoform X2 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of hemicentin-1 isoform X2 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of hemicentin-1 isoform X2 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of hemicentin-1 isoform X2 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of hemicentin-1 isoform X2 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 5
BLAST of hemicentin-1 isoform X2 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 0
BLAST of hemicentin-1 isoform X2 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of hemicentin-1 isoform X2 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of hemicentin-1 isoform X2 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30028839 ID=SMED30028839|Name=hemicentin-1 isoform X2|organism=Schmidtea mediterranea sexual|type=transcript|length=3766bpback to top protein sequence of SMED30028839-orf-1 >SMED30028839-orf-1 ID=SMED30028839-orf-1|Name=SMED30028839-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=1186bp MEYFKTFILITLFGNLMDRSYTLNFLITPNNATVNSKENLTLECVVDQQNback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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