BTAF1 RNA polymerase II, B-TFIID transcription factor-associated

Query: 3374 GAIELIYLVCHS---GLLPYRLAIAVIILPVVLACLNAPFDPLRRVATHVFSXXXXXXXXESSGADLSILTPARQQQRKQHLSFLDSLLNPKLIGQYNAHHSVVSAKLRQYQEEGVNWLGFLNRYGLHGVLADDMGLGKTLQAICVIAG-------EYSRAP-STCPP--SLIVCPPTLTVHWHQEFKKFLVNLPDFNTIVYLGTPMYRQCIFNSLSRYQVVITSYDTLRSDMNLLARPTFPRCGTDVTKGSLMANSNVWNYVVLDEGHLIRNYKSKVAVATRALCARHRLVLTGTPIQNRVGELWSLFDFLMPGLLGTCTEFNRRYGRVLEQNGSNSGRKVDSEAGTLALELLHRQVLPFMLRRVKDDVLQELPPKIMQDYMCTMSPLQLRLYTHCMESQAATDTDFVELVDKSY----KENSAINQHRHGFQTMHYLRLVCNHPSLGLTSSHPLYRTLMRELAANNQCLDDINLSGKLVALRQLILDCGVGVSGAGEEELDETSVVASNRLLVFCQSIKMMELVD-KMIRNEIPKATHLRLDGSVPAKDRQQIVEKFSCDAXXXXXXXXXXXXXXXXXXXXANIVIFVEHDWNPMRDLQAMDRAHRIGQKHTVIVYRLITAQSIEEKIMNLQEFKKFLANAVVSKDNNQMASMNTENILEIMNKEANWPTQSPPASANGKQKVVSSVSGGTETQLGSKSVLSKISKADSGERVYDCLDEYDQEYNLDSFV 5515
            GAIE +  V      G++PY   I ++++PV L  ++   D +R +AT  F+ L+ L+PLE+   D   ++    Q + +   FL+ LL+ K +  Y     + +A+LR+YQ++GVNWL FLN+Y LHG+L DDMGLGKTLQ+IC++AG       EY+R+  + C P  SL+VCPPTLT HW  E  KF  +    N + Y G P  R  + + + R+ +++ SYD +R+D++      F                   NY +LDEGH+I+N K+K++ A + L A +R++L+GTPIQN V ELWSLFDFLMPG LGT  +F  RYG+ +  +        + EAG LA++ LHRQVLPF+LRR+K+DVLQ+LPPKI+QDY CT+SPLQ++LY    +S+A  D D  E V  +      E   +    H FQ + YLR +CNHP+L LT  HP ++T   +LA  N  L DI  + KL AL+QL+LDCG+G +G+  E   E SVVA +R+L+FCQ   M+++V+  +++  +P  T+LRLDGS+P   R  IV +F+ D SID+LLLTT +GGLGLNLT A+ V+FVEHDWNPMRDLQAMDRAHRIGQK  V VYRLIT  ++EEKIM LQ+FK  +AN V+S++N+ + SM T+ +L++   + +   +    S +GK  +              KS+L  +S       ++D  ++YD EY+L++F+
Sbjct: 1164 GAIEALACVMEQLDVGIVPY---IVLLVVPV-LGRMSDQTDSVRFMATQCFATLIRLMPLEAGIPDPPNMSAELIQLKAKERHFLEQLLDGKKLENYKIPVPI-NAELRKYQQDGVNWLAFLNKYKLHGILCDDMGLGKTLQSICILAGDHCHRAQEYARSKLAECMPLPSLVVCPPTLTGHWVDEVGKF-CSREYLNPLHYTGPPTERIRLQHQVKRHNLIVASYDVVRNDIDFFRNIKF-------------------NYCILDEGHVIKNGKTKLSKAVKQLTANYRIILSGTPIQNNVLELWSLFDFLMPGFLGTERQFAARYGKPILASRDARSSSREQEAGVLAMDALHRQVLPFLLRRMKEDVLQDLPPKIIQDYYCTLSPLQVQLYEDFAKSRAKCDVD--ETVSSATLSEETEKPKLKATGHVFQALQYLRKLCNHPALVLTPQHPEFKTTAEKLAVQNSSLHDIQHAPKLSALKQLLLDCGLG-NGSTSESGTE-SVVAQHRILIFCQLKSMLDIVEHDLLKPHLPSVTYLRLDGSIPPGQRHSIVSRFNNDPSIDVLLLTTHVGGLGLNLTGADTVVFVEHDWNPMRDLQAMDRAHRIGQKRVVNVYRLITRGTLEEKIMGLQKFKMNIANTVISQENSSLQSMGTDQLLDLFTLDKDGKAEKADTSTSGKASM--------------KSILENLSD------LWD-QEQYDSEYSLENFM 1845          

Query:   86 SRLDKLFELLESNHQNI-RNAAAIQIGQLSANNQVNISALLAKLLPYAKHKIWVVRIAASDAVRHIGNNAKLWVP-------GTSESNVTN--VSNLINLENLNLHDILKIGTRLYSRDFKDLD-------EANTNQNINRDE--LARHLGF------------LIPDE---------CEIKNLITVKDCELVES--------KSENK---MSVELAVMKSM------ENSPKKPVKRPHEEVQDV-----NEPGTKMKC-VEKIGNETER-ERNTEWPWVDFCEELLKNLWDAKWEIRHGAATCLRELIRSQGSIMLPKNANISSTDKFAACHERFQEEIVVRLLCTLTLDQLSDFVSDEMVAPVRESCAQALGVISVHLTRRLVEILANQLLSLLNHDEWRVNHXXXXXXXXXXXXRMDLVEVLLPIIYDPISSHLKGNXXXXXXXXXXXXLMPLFGDCCSNTVAISNEELDTLKTDLWDVLAVRIDCTTSGATCAVLQLLERLYEKCNVVYNQSEDQPMATDRVKALNEYINRLHWCYFNYSDLVRLAAVRTCRAVLQSIGIKVGTILEHGTIXXXXXXXXXXXXIDDNCQVAAEA------HSVWNQFIDSLPEQLLARVSCERLEIWMCSAMQPARLSYTPGSILMPDYIIXXXXXXXXXXXXDGLDEDDGNKHHILTEFYIGGRESFITDGSSAARDDLVXXXXXXXXXXXXXXXXXFIFHEAGIRNILISI-----IAQI---HLKDRLAVQRFVASMILAYWDPDHLLAMRNLNDCSLSPLQSQLLTALEEPIYYQEILSQFKQMHKACRDLI 2314
            SRLD+LF LL++    + R AAA Q+G++   +   ++ LL+K+L Y +   W  RIAA  AV  I  N   W P        TSES++ +   +  +N +  ++  +L+ G  L      + +       E +  + I R    L + LG             L  DE           +    T++  EL++S        + +NK   M+   A  +S       E S       P E+ + +     N+     K  ++ I + +   E   EWP   FCEEL  +L++  WE+RHGA T LRE++++ G          S+ ++    H+ + E++V+RLLC   LD+  DFVSDE+VAPVRE+CAQ LGV+  H+    V    + LL LL  ++W V HG LLG+KY LA R D++  LLP +   I   L+ + DDDVR  A A+L+P+      + V +  +++  +   LWD L    D T S  T +++ LL  L     + Y Q +   +     ++L   + R+ W + +++    +++VR  RA L+++   + T  ++ +   +         I   C + +        H VW + +     Q +   +C  +  W+C  MQP+ L          D  +     A A     G      +++  + + YI G ++ + D   A RD +V+RAR+ A +LL  LC      + G+  +   I     + Q+   HL  + A+QR   ++++  W      A++         +Q +LL  L E +YY EI   F +M   C+ LI
Sbjct:    4 SRLDRLFILLDTGTTPVTRKAAAQQLGEVVKLHPHELNNLLSKVLIYLRSANWDTRIAAGQAVEAIVKNVPEWNPVPRTRQEPTSESSMEDSPTTERLNFDRFDICRLLQHGASLLGSAGAEFEVQDEKSGEVDPKERIARQRKLLQKKLGLNMGEAIGMSTEELFNDEDLDYTPTSASFVNKQPTLQAAELIDSEFRAGMSNRQKNKAKRMAKLFAKQRSRDAVETNEKSNDSTDGEPEEKRRKIANVVINQSANDSKVLIDNIPDSSSLIEETNEWPLESFCEELCNDLFNPSWEVRHGAGTGLREILKAHGKS--GGKMGDSTLEEMIQQHQEWLEDLVIRLLCVFALDRFGDFVSDEVVAPVRETCAQTLGVVLKHMNETGVHKTVDVLLKLLTQEQWEVRHGGLLGIKYALAVRQDVINTLLPKVLTRIIEGLQ-DLDDDVRAVAAASLVPVV----ESLVYLQTQKVPFIINTLWDALLELDDLTAS--TNSIMTLLSSL-----LTYPQVQQCSIQ----QSLTVLVPRV-WPFLHHT----ISSVR--RAALETLFTLLSTQDQNSSSWLIPILPDMLRHIFQFCVLESSQEILDLIHKVWMELLSKASVQYVVAAACPWMGAWLCLMMQPSHLPI--------DLNMLLEVKARAKEKTGGKVRQGQSQNKEVLQEYIAGADTIMED--PATRDFVVMRARMMAAKLLGALCCCIC--DPGVNVVTQEIKPAESLGQLLLFHLNSKSALQRISVALVICEW-----AALQKECKAVTLAVQPRLLDILSEHLYYDEIAVPFTRMQNECKQLI 782          

Query: 3374 GAIELIYLVCHS---GLLPYRLAIAVIILPVVLACLNAPFDPLRRVATHVFSXXXXXXXXESSGADLSILTPARQQQRKQHLSFLDSLLNPKLIGQYNAHHSVVSAKLRQYQEEGVNWLGFLNRYGLHGVLADDMGLGKTLQAICVIAG-------EYSRAP-STCPP--SLIVCPPTLTVHWHQEFKKFLVNLPDFNTIVYLGTPMYRQCIFNSLSRYQVVITSYDTLRSDMNLLARPTFPRCGTDVTKGSLMANSNVWNYVVLDEGHLIRNYKSKVAVATRALCARHRLVLTGTPIQNRVGELWSLFDFLMPGLLGTCTEFNRRYGRVLEQNGSNSGRKVDSEAGTLALELLHRQVLPFMLRRVKDDVLQELPPKIMQDYMCTMSPLQLRLYTHCMESQAATDTDFVELVDKSY----KENSAINQHRHGFQTMHYLRLVCNHPSLGLTSSHPLYRTLMRELAANNQCLDDINLSGKLVALRQLILDCGVGVSGAGEEELDETSVVASNRLLVFCQSIKMMELVD-KMIRNEIPKATHLRLDGSVPAKDRQQIVEKFSCDAXXXXXXXXXXXXXXXXXXXXANIVIFVEHDWNPMRDLQAMDRAHRIGQKHTVIVYRLITAQSIEEKIMNLQEFKKFLANAVVSKDNNQMASMNTENILEIMNKEANWPTQSPPASANGKQKVVSSVSGGTETQLGSKSVLSKISKADSGERVYDCLDEYDQEYNLDSFV 5515
            GAIE +  V      G++PY   I ++++PV L  ++   D +R +AT  F+ L+ L+PLE+   D   ++    Q + +   FL+ LL+ K +  Y     + +A+LR+YQ++GVNWL FLN+Y LHG+L DDMGLGKTLQ+IC++AG       EY+R+  + C P  SL+VCPPTLT HW  E  KF  +    N + Y G P  R  + + + R+ +++ SYD +R+D++      F                   NY +LDEGH+I+N K+K++ A + L A +R++L+GTPIQN V ELWSLFDFLMPG LGT  +F  RYG+ +  +        + EAG LA++ LHRQVLPF+LRR+K+DVLQ+LPPKI+QDY CT+SPLQ++LY    +S+A  D D  E V  +      E   +    H FQ + YLR +CNHP+L LT  HP ++T   +LA  N  L DI  + KL AL+QL+LDCG+G +G+  E   E SVVA +R+L+FCQ   M+++V+  +++  +P  T+LRLDGS+P   R  IV +F+ D SID+LLLTT +GGLGLNLT A+ V+FVEHDWNPMRDLQAMDRAHRIGQK  V VYRLIT  ++EEKIM LQ+FK  +AN V+S++N+ + SM T+ +L++   + +   +    S +GK  +              KS+L  +S       ++D  ++YD EY+L++F+
Sbjct: 1164 GAIEALACVMEQLDVGIVPY---IVLLVVPV-LGRMSDQTDSVRFMATQCFATLIRLMPLEAGIPDPPNMSAELIQLKAKERHFLEQLLDGKKLENYKIPVPI-NAELRKYQQDGVNWLAFLNKYKLHGILCDDMGLGKTLQSICILAGDHCHRAQEYARSKLAECMPLPSLVVCPPTLTGHWVDEVGKF-CSREYLNPLHYTGPPTERIRLQHQVKRHNLIVASYDVVRNDIDFFRNIKF-------------------NYCILDEGHVIKNGKTKLSKAVKQLTANYRIILSGTPIQNNVLELWSLFDFLMPGFLGTERQFAARYGKPILASRDARSSSREQEAGVLAMDALHRQVLPFLLRRMKEDVLQDLPPKIIQDYYCTLSPLQVQLYEDFAKSRAKCDVD--ETVSSATLSEETEKPKLKATGHVFQALQYLRKLCNHPALVLTPQHPEFKTTAEKLAVQNSSLHDIQHAPKLSALKQLLLDCGLG-NGSTSESGTE-SVVAQHRILIFCQLKSMLDIVEHDLLKPHLPSVTYLRLDGSIPPGQRHSIVSRFNNDPSIDVLLLTTHVGGLGLNLTGADTVVFVEHDWNPMRDLQAMDRAHRIGQKRVVNVYRLITRGTLEEKIMGLQKFKMNIANTVISQENSSLQSMGTDQLLDLFTLDKDGKAEKADTSTSGKASM--------------KSILENLSD------LWD-QEQYDSEYSLENFM 1845          

Query:  137 RNAAAIQIGQLSANNQVNISALLAKLLPYAKHKIWVVRIAASDAVRHIGNNAKLWVP-------GTSESNVTN--VSNLINLENLNLHDILKIGTRLYSRDFKDLD-------EANTNQNINRDE--LARHLGF------------LIPDE---------CEIKNLITVKDCELVES--------KSENK---MSVELAVMKSM------ENSPKKPVKRPHEEVQDV-----NEPGTKMKC-VEKIGNETER-ERNTEWPWVDFCEELLKNLWDAKWEIRHGAATCLRELIRSQGSIMLPKNANISSTDKFAACHERFQEEIVVRLLCTLTLDQLSDFVSDEMVAPVRESCAQALGVISVHLTRRLVEILANQLLSLLNHDEWRVNHXXXXXXXXXXXXRMDLVEVLLPIIYDPISSHLKGNXXXXXXXXXXXXLMPLFGDCCSNTVAISNEELDTLKTDLWDVLAVRIDCTTSGATCAVLQLLERLYEKCNVVYNQSEDQPMATDRVKALNEYINRLHWCYFNYSDLVRLAAVRTCRAVLQSIGIKVGTILEHGTIXXXXXXXXXXXXIDDNCQVAAEA------HSVWNQFIDSLPEQLLARVSCERLEIWMCSAMQPARLSYTPGSILMPDYIIXXXXXXXXXXXXDGLDEDDGNKHHILTEFYIGGRESFITDGSSAARDDLVXXXXXXXXXXXXXXXXXFIFHEAGIRNILISI-----IAQI---HLKDRLAVQRFVASMILAYWDPDHLLAMRNLNDCSLSPLQSQLLTALEEPIYYQEILSQFKQMHKACRDLI 2314
            R AAA Q+G++   +   ++ LL+K+L Y +   W  RIAA  AV  I  N   W P        TSES++ +   +  +N +  ++  +L+ G  L      + +       E +  + I R    L + LG             L  DE           +    T++  EL++S        + +NK   M+   A  +S       E S       P E+ + +     N+     K  ++ I + +   E   EWP   FCEEL  +L++  WE+RHGA T LRE++++ G          S+ ++    H+ + E++V+RLLC   LD+  DFVSDE+VAPVRE+CAQ LGV+  H+    V    + LL LL  ++W V HG LLG+KY LA R D++  LLP +   I   L+ + DDDVR  A A+L+P+      + V +  +++  +   LWD L    D T S  T +++ LL  L     + Y Q +   +     ++L   + R+ W + +++    +++VR  RA L+++   + T  ++ +   +         I   C + +        H VW + +     Q +   +C  +  W+C  MQP+ L          D  +     A A     G      +++  + + YI G ++ + D   A RD +V+RAR+ A +LL  LC      + G+  +   I     + Q+   HL  + A+QR   ++++  W      A++         +Q +LL  L E +YY EI   F +M   C+ LI
Sbjct:   22 RKAAAQQLGEVVKLHPHELNNLLSKVLIYLRSANWDTRIAAGQAVEAIVKNVPEWNPVPRTRQEPTSESSMEDSPTTERLNFDRFDICRLLQHGASLLGSAGAEFEVQDEKSGEVDPKERIARQRKLLQKKLGLNMGEAIGMSTEELFNDEDLDYTPTSASFVNKQPTLQAAELIDSEFRAGMSNRQKNKAKRMAKLFAKQRSRDAVETNEKSNDSTDGEPEEKRRKIANVVINQSANDSKVLIDNIPDSSSLIEETNEWPLESFCEELCNDLFNPSWEVRHGAGTGLREILKAHGKS--GGKMGDSTLEEMIQQHQEWLEDLVIRLLCVFALDRFGDFVSDEVVAPVRETCAQTLGVVLKHMNETGVHKTVDVLLKLLTQEQWEVRHGGLLGIKYALAVRQDVINTLLPKVLTRIIEGLQ-DLDDDVRAVAAASLVPVV----ESLVYLQTQKVPFIINTLWDALLELDDLTAS--TNSIMTLLSSL-----LTYPQVQQCSIQ----QSLTVLVPRV-WPFLHHT----ISSVR--RAALETLFTLLSTQDQNSSSWLIPILPDMLRHIFQFCVLESSQEILDLIHKVWMELLSKASVQYVVAAACPWMGAWLCLMMQPSHLPI--------DLNMLLEVKARAKEKTGGKVRQGQSQNKEVLQEYIAGADTIMED--PATRDFVVMRARMMAAKLLGALCCCIC--DPGVNVVTQEIKPAESLGQLLLFHLNSKSALQRISVALVICEW-----AALQKECKAVTLAVQPRLLDILSEHLYYDEIAVPFTRMQNECKQLI 782          

Query: 3683 KLRQYQEEGVNWLGFLNRYGLHGVLADDMGLGKTLQAICVIAG-EYSRAPSTCP--------PSLIVCPPTLTVHWHQEFKKFLVNLPDFNTIVYLGTPMY----RQCIFNSLSRYQVVITSYDTLRSDMNLLARPTFPRCGTDVTKGSLMANSNVWNYVVLDEGHLIRNYKSKVAVATRALCARHRLVLTGTPIQNRVGELWSLFDFLMPGLLGTCTEFNRRYGRVLEQNGSNSGRKVDSEAGTLALELLHRQVLPFMLRRVKDDVLQEL--PPKIMQDYMCTMSPLQLRLYTHCMESQAATDTDFVELVDKSYKENSAINQHRHGFQTMHYLRLVCNHPSLGLTSSHPLYRTLMRELAANNQCLDDINLSGKLVALRQLILDCGVGVSGAGEEELDETSVVASNRLLVFCQSIKMMELVDKMIRNEIPKATHLRLDGSVPAKDRQQIVEKFSCDAXXXXXXXXXXXXXXXXXXXXANIVIFVEHDWNPMRDLQAMDRAHRIGQKHTVIVYRLITAQSIEEKIMNLQEFKKFLANAVVSKDNNQMASMNTENILEIMNKEANWPTQSPPASA 5356
            KL +YQ+ GV WL  L+     G+L D+MGLGKT+Q I  +AG  YS+  +           P++IVCP T+   W +EF  +    P F   +   T  Y     + I +    + ++ITSY  +R   + ++R                     W+YV+LDEGH IRN  + V +A +     HR++L+G+P+QN + ELWSLFDF+ PG LGT   F  ++   +   G ++   V  +       +L   + P++LRR+K DV   L  P K  Q   C ++  Q ++Y + ++S+              Y+    +N     F  +  LR +CNHP L       L      EL  +         SGK++ +  L+                +       R+L+F QS +M+++++  +R +  K T+L++DG+     RQ ++ +++ D SI + LLTT +GGLG+NLT AN V+  + DWNP  D QA +RA RIGQK  V VYRL+TA +IEEKI + Q FK+FL N V+ KD  Q     + ++ E+    +   +QS   SA
Sbjct:  506 KLFKYQQTGVRWLWELHCQQAGGILGDEMGLGKTIQIIAFLAGLSYSKIRTRGSNYRFEGLGPTVIVCPTTVMHQWVKEFHTWW---PPFRVAILHETGSYTHKKEKLIRDVAHCHGILITSYSYIRLMQDDISRYD-------------------WHYVILDEGHKIRNPNAAVTLACKQFRTPHRIILSGSPMQNNLRELWSLFDFIFPGKLGTLPVFMEQFSVPITMGGYSNASPVQVKTAYKCACVLRDTINPYLLRRMKSDVKMSLSLPDKNEQVLFCRLTDEQHKVYQNFVDSKEV------------YR---ILNGEMQIFSGLIALRKICNHPDLFSGGPKNLKGLPDDELEEDQ--FGYWKRSGKMIVVESLL----------------KIWHKQGQRVLLFSQSRQMLDILEVFLRAQ--KYTYLKMDGTTTIASRQPLITRYNEDTSIFVFLLTTRVGGLGVNLTGANRVVIYDPDWNPSTDTQARERAWRIGQKKQVTVYRLLTAGTIEEKIYHRQIFKQFLTNRVL-KDPKQRRFFKSNDLYELFTLTSPDASQSTETSA 1020          

Query: 3671 VVSAKLRQYQEEGVNWLGFLNRYGLHGVLADDMGLGKTLQAICVIA--GEYSRAPSTCPPSLIVCPPTLTVHWHQEFKKFLVNLPDFNTIVYLGTPMYRQCIFNSL--SRYQVVITSYDTLRSDMNLLARPTFPRCGTDVTKGSLMANSNVWNYVVLDEGHLIRNYKSKVA-VATRALCARHRLVLTGTPIQNRVGELWSLFDFLMPGLLGTCTEFNRRYGRVLEQNGSNSGRKVD--SEAGTLALELLHRQVLPFMLRRVKDDVLQELPPKIMQDYMCTMSPLQLRLYTHCMESQAATDTDFVELVDKSYKENSAINQHRHGFQTMHYLRLVCNHPSLGLTSSHPLYRTLMRELAANNQCLDDINLSGKLVALRQLILDCGVGVSGAGEEELDETSVVASN-RLLVFCQSIKMMELVDKMIRNEIPKATHLRLDGSVPAKDRQQIVEKFS-CDAXXXXXXXXXXXXXXXXXXXXANIVIFVEHDWNPMRDLQAMDRAHRIGQKHTVIVYRLITAQSIEEKIMNLQEFK 5230
            +V+  L+QYQ +G+ WL  L    L+G+LAD+MGLGKT+Q I +I    E+ R      P LI+ P +   +W  EF K+    P    + Y G+P  R+     L   ++ V++T+Y+ +  D ++LA+                     W Y+++DEGH ++N+  K+  V      A  RL+LTGTP+QN++ ELW+L +FL+P +  +C+ F + +        + +G KVD   E   L +  LH+ + PF+LRR+K +V  +LP K+     C MS LQ  LY H M+++    TD  E   K       +        T+  LR +CNHP +        +   +       Q LD    SGK   L +++                   + A+N ++L+FCQ   +M +++        K  +LRLDG+  A+DR  +++ F+   +   I LL+T  GGLGLNL SA+ VI  + DWNP +DLQA DRAHRIGQ++ V V RL T  S+EEKI+   ++K
Sbjct:  245 MVNGVLKQYQIKGLEWLVSLYNNNLNGILADEMGLGKTIQTIALITYLMEHKRING---PFLIIVPLSTLSNWAYEFDKWA---PSVVKVSYKGSPAARRAFVPQLRSGKFNVLLTTYEYIIKDKHILAKIR-------------------WKYMIVDEGHRMKNHHCKLTQVLNTHYVAPRRLLLTGTPLQNKLPELWALLNFLLPTIFKSCSTFEQWFNAPF----AMTGEKVDLNEEETILIIRRLHKVLRPFLLRRLKKEVEAQLPEKVEYVIKCDMSALQRVLYRH-MQAKGVLLTDGSEKDKKGKGGTKTL------MNTIMQLRKICNHPYM-FQHIEESFSEHLGFTGGIVQGLDLYRASGKFELLDRIL-----------------PKLRATNHKVLLFCQMTSLMTIMEDYFAYRGFK--YLRLDGTTKAEDRGMLLKTFNEPGSEYFIFLLSTRAGGLGLNLQSADTVIIFDSDWNPHQDLQAQDRAHRIGQQNEVRVLRLCTVNSVEEKILAAAKYK 717          

Query: 3671 VVSAKLRQYQEEGVNWLGFLNRYGLHGVLADDMGLGKTLQAICVIA--GEYSRAPSTCPPSLIVCPPTLTVHWHQEFKKFLVNLPDFNTIVYLGTPMYRQCIFNSL--SRYQVVITSYDTLRSDMNLLARPTFPRCGTDVTKGSLMANSNVWNYVVLDEGHLIRNYKSKVA-VATRALCARHRLVLTGTPIQNRVGELWSLFDFLMPGLLGTCTEFNRRYGRVLEQNGSNSGRKVD--SEAGTLALELLHRQVLPFMLRRVKDDVLQELPPKIMQDYMCTMSPLQLRLYTHCMESQAATDTDFVELVDKSYKENSAINQHRHGFQTMHYLRLVCNHPSLGLTSSHPLYRTLMRELAANNQCLDDINLSGKLVALRQLILDCGVGVSGAGEEELDETSVVASN-RLLVFCQSIKMMELVDKMIRNEIPKATHLRLDGSVPAKDRQQIVEKFS-CDAXXXXXXXXXXXXXXXXXXXXANIVIFVEHDWNPMRDLQAMDRAHRIGQKHTVIVYRLITAQSIEEKIMNLQEFK 5230
            +V+  L+QYQ +G+ WL  L    L+G+LAD+MGLGKT+Q I +I    E+ R      P LI+ P +   +W  EF K+    P    + Y G+P  R+     L   ++ V++T+Y+ +  D ++LA+                     W Y+++DEGH ++N+  K+  V      A  RL+LTGTP+QN++ ELW+L +FL+P +  +C+ F + +        + +G KVD   E   L +  LH+ + PF+LRR+K +V  +LP K+     C MS LQ  LY H M+++    TD  E   K       +        T+  LR +CNHP +        +   +       Q LD    SGK   L +++                   + A+N ++L+FCQ   +M +++        K  +LRLDG+  A+DR  +++ F+   +   I LL+T  GGLGLNL SA+ VI  + DWNP +DLQA DRAHRIGQ++ V V RL T  S+EEKI+   ++K
Sbjct:  178 MVNGVLKQYQIKGLEWLVSLYNNNLNGILADEMGLGKTIQTIALITYLMEHKRING---PFLIIVPLSTLSNWAYEFDKWA---PSVVKVSYKGSPAARRAFVPQLRSGKFNVLLTTYEYIIKDKHILAKIR-------------------WKYMIVDEGHRMKNHHCKLTQVLNTHYVAPRRLLLTGTPLQNKLPELWALLNFLLPTIFKSCSTFEQWFNAPF----AMTGEKVDLNEEETILIIRRLHKVLRPFLLRRLKKEVEAQLPEKVEYVIKCDMSALQRVLYRH-MQAKGVLLTDGSEKDKKGKGGTKTL------MNTIMQLRKICNHPYM-FQHIEESFSEHLGFTGGIVQGLDLYRASGKFELLDRIL-----------------PKLRATNHKVLLFCQMTSLMTIMEDYFAYRGFK--YLRLDGTTKAEDRGMLLKTFNEPGSEYFIFLLSTRAGGLGLNLQSADTVIIFDSDWNPHQDLQAQDRAHRIGQQNEVRVLRLCTVNSVEEKILAAAKYK 650          

Query: 3437 AVIILPVVLACLNAPFDPLRRVATHVFSXXXXXXXXESSGADLSILTPARQQQRKQHLSFLDSLLNPKLIGQY---NAHHSVVSAKLRQYQEEGVNWLGFLNRYGLHGVLADDMGLGKTLQAICVIAGEYSRAPST----CPPSLIVCPPTLTVHWHQEFKKFLVNLPDFNTIVYLGTPMYRQCIFNSLSR---YQVVITSYDTLRSDMNLLARPTFPRCGTDVTKGSLMANSNVWNYVVLDEGHLIRNYKSKVAVATRALCARHRLVLTGTPIQNRVGELWSLFDFLMPGLLGTCTEFNRRYGRVLEQNGSNSGRKVDSEAGTLALELLHRQVLPFMLRRVKDDVLQELPPKIMQDYMCTMSPLQLRLY----THCMESQAATDTDFVELVDKSYKENSAINQHRHGFQTMHYLRLVCNHPSLGLTS----SHPLYRTLMRELAANNQCLDDINLSGKLVALRQLILDCGVGVSGAGEEELDETS---VVASNRLLVFCQSIKMMELV-DKMIRNEIPKA-THLRLDGSVPAKDRQQIVEKFSCDAXXXXXXXXXXXXXXXXXXXXANIVIFVEHDWNPMRDLQAMDRAHRIGQKHTVIVYRLITAQSIEEKIMNLQEFKKFLANAVVSKDNNQMASMNTENILEIMNKEANWPTQSPPASANGKQKVVSSVSGGTETQLGS 5416
            A ++ PV+   L    + +R  A   F  L+ ++ LE+    +  ++     ++ ++ +F++ L +P  + +    +      ++ LR+YQ EG+ W+ FL  YGLHG+LADDMGLGKTLQ +C IA    R   +    C  SLIVCP TL  HW  E+ +F                  R     +L+R    ++ + +YD L++   +                       VWNY+VLDEGH++RN K +       L  + RL+L+GTP+QN   +LWSLF +LMPG LG+  +F  ++ + + +       + D +AG+ A+  LH+ VLPF++RR+K +VL+ELP K +QDY C ++  Q  +Y      C  SQ   D     LV                  T+  LR + +H  L   +      P Y  L + LAA          SGK+ AL+QL+++C +  +   E E  E     V + +R L+FCQ     +LV D +   E     +HL LDGSVPA DR ++V +F+ D +ID+L+LTT +GG+GLNLT A+ VIF++HDWNPM+DLQA+DRAHR+GQ   V VYRLIT  ++EEK+M+L +FK   A A++  DN  M +M T  ++ +   + +   + P       +K   S     E  L S
Sbjct: 1016 ATLLAPVIFPLLADQCETVRDAAGEAFRRLIPVITLENPDFSIEGMSQELLAKKSEYSNFINVLGSPSSLPRVIRADIRGGFDTSMLREYQLEGITWIRFLRTYGLHGILADDMGLGKTLQTMCSIALSVDRDEMSEFHRC--SLIVCPRTLVDHWCLEWNRFFPQ---------------RVPASKNLTRCHGAEICVIAYDELKTAYMM---------------------DRVWNYIVLDEGHVMRNSKLRAWKFASQLVGKSRLILSGTPVQNSPADLWSLFAWLMPGYLGSEKQFRSQFLKKIMKCRLPKANEADLKAGSAAISQLHKLVLPFVMRRLKTEVLKELPEKNVQDYECELTEDQKEIYRFVVDRCTSSQE--DVGLSSLV------------------TLITLRKLTDHTKLVHDTLAKIGAPQY-ILSKALAAK---------SGKMEALKQLLIECEICKNPDEEVEQPEDLGGLVASGHRALIFCQWKTSAKLVSDALKSGEFGSVVSHLVLDGSVPAGDRMKMVNRFNEDKTIDVLILTTHVGGVGLNLTGADTVIFLDHDWNPMKDLQAIDRAHRLGQTRNVNVYRLITQGTVEEKVMSLAKFKLNTAQALIGADNTSMMTMETGELMNMFTLDGDEAKKKPGGGEPAAKKSKKSTGAPEEVDLAS 1630          

Query:   77 NMASRLDKLFELLESNHQNIRNAAAIQIGQLSANNQVNISALLAKLLPYAKHKIWVVRIAASDAVRHIGNNAKLWVPGTSESNVTNVSNLINLENLNLHDILKIGTRLYSRDFKDLDEANTNQNINRDELARHLGFLIPDECEIKNLITVKDCELVESKSENKMSVELAVMKSMENSPKKPVKRPHEEVQDVNEPGTKM---KCVEKI-------GN---ETERERNTEWPWVDFCEELLKNLWDAKWEIRHGAATCLRELIRSQGSIMLPKNANISSTDKFAACHERFQEEIVVRLLCTLTLDQLSDFVSDE-MVAPVRESCAQALGVISVHLTR 1042
            + ++RL +L  LLE+ + N+RN AA   G+LS  ++ ++   L K   +A  ++W  R++A  A++    NA  +    +E + ++VS   N+ ++ + ++L+    L S D   L ++  ++  N+                       K  E+V+   E   +  ++  K + +      +  H+ + + ++P T     + V KI       GN     ER++     ++    EL+  + + +W  RHG A  +                 I+ST      +E   + I+  L+  L LD+ +DF+S     APVRE CAQAL    VH+ R
Sbjct:    4 DTSARLLQLDPLLEAKNPNVRNEAAAAFGKLSILSE-DVKNSLKK---HAASQLWETRVSAGKALQATLQNAPEFERLKNEED-SSVSE--NVRSIVVMNVLRSFKPLLSDDESALKKSEKDRGNNQ-----------------------KQREIVDQHLEYNRATGISSTKFLSDD-----EFLHQGISEPDQPSTSKELDEVVTKIEIFDEENGNCDDGIERQKK----FLKVLRELVNLVAEKQWYARHGGAIAI---------------CQIASTSYDRLSYELI-DTILYLLIHVLILDKFNDFISGRNATAPVREQCAQAL----VHMLR 280          

Query: 3671 VVSAKLRQYQEEGVNWLGFLNRYGLHGVLADDMGLGKTLQAICVIAGEYSRAPSTCPPSLIVCPPTLTVHWHQEFKKFLVNLPDFNTIVYLGTPMYRQCIFNSL---SRYQVVITSYDTLRSDMNLLARPTFPRCGTDVTKGSLMANSNVWNYVVLDEGHLIRNYKSKVAVATRALCARHRLVLTGTPIQNRVGELWSLFDFLMPGLLGTCTEFNRRYGRVLEQNGSNSGRKVDSEAGTLALELLHRQVLPFMLRRVKDDVLQELPPKIMQDYMCTMSPLQLRLYTHCMESQAATDTDFVELVDKSYKENSAINQHRHGFQTMHYLRLVCNHPSL--GLTSSHPLYRTLMRELAANNQCLDDINLSGKLVALRQLILDCGVGVSGAGEEELDETSVVASNRLLVFCQSIKMMELVDKMIRNEIPKATHLRLDGSVPAKDRQQIVEKFSC-DAXXXXXXXXXXXXXXXXXXXXANIVIFVEHDWNPMRDLQAMDRAHRIGQKHTVIVYRLITAQSIEEKIMNLQEFKKFLANAVVSK 5260
            + + ++R YQ  G+NWL  L    ++G+LAD+MGLGKTLQ I +I G      +   P L++ P +   +W  EFKK+    P  N +V +G    R  +   +    ++ V  T+Y+     M L  +    +                W Y+++DE H I+N KSK++   R L + +RL++TGTP+QN + ELW+L +FL+P +  +  +F+  +      N + SG        T  ++ LH+ + PF+LRR+K DV + L PK        +S +Q   YT  +      D D +    K       + + R     MH LR   NHP L  G     P            +Q L  ++ SGK+V L +L++      S                R+L+F Q  +M++L++           + RLDGS P +DR   +E ++  D+   I +LTT  GGLG+NL +A++VI  + DWNP  DLQAMDRAHRIGQK  V V+RLIT  +++E+I+   E K  L N V+ +
Sbjct:  127 IENGEMRDYQVRGLNWLASLQHNKINGILADEMGLGKTLQTISMI-GYMKHYKNKASPHLVIVPKSTLQNWANEFKKWC---PSINAVVLIGDEAARNQVLRDVILPQKFDVCCTTYE-----MMLKVKTQLKKLN--------------WRYIIIDEAHRIKNEKSKLSETVRELNSENRLLITGTPLQNNLHELWALLNFLLPDIFTSSDDFDSWFS-----NDAMSG-------NTDLVQRLHKVLQPFLLRRIKSDVEKSLLPKKEVKVYVGLSKMQREWYTKVL----MKDIDIINGAGK-------VEKARLMNILMH-LRKCVNHPYLFDGAEPGPPF---------TTDQHL--VDNSGKMVVLDKLLMKFKEQGS----------------RVLIFSQFSRMLDLLEDFCW--WRHYEYCRLDGSTPHEDRSNAIEAYNAPDSKKFIFMLTTRAGGLGINLATADVVIIYDSDWNPQSDLQAMDRAHRIGQKKQVRVFRLITENTVDERIIEKAEAKLRLDNIVIQQ 586          

Query: 3677 SAKLRQYQEEGVNWLGFLNRYGLHGVLADDMGLGKTLQAICVIAGEYSRAPSTCPPSLIVCPPTLTVHWHQEFKKFLVNLPDFNTIVYLGTPMYRQCIFNSL---SRYQVVITSYDTLRSDMNLLARPTFPRCGTDVTKGSLMANSNVWNYVVLDEGHLIRNYKSKVA--VATRALCARHRLVLTGTPIQNRVGELWSLFDFLMPGLLGTCTEFNRRYGRVLEQNGSNSGRKVD--SEAGTLALELLHRQVLPFMLRRVKDDVLQELPPKIMQDYMCTMSPLQLRLYTHCMESQAATDTDFVELVDKSYKENSAINQHRHGFQTMHYLRLVCNHPSLGLTSSHPLYRTL--MRELAANNQCLDDINLSGKLVALRQLILDCGVGVSGAGEEELDETSVVASNRLLVFCQSIKMMELVDKMIRNEIPKATHLRLDGSVPAKDRQQIVEKFSC-DAXXXXXXXXXXXXXXXXXXXXANIVIFVEHDWNPMRDLQAMDRAHRIGQKHTVIVYRLITAQSIEEKIMNLQEFKKFLANAVV--SKDNNQMASMNTENILE 5305
            S KL+ YQ +G+ W+  L    L+G+LAD+MGLGKT+Q I  I         T  P L++ P +   +W  EF K+  N+   + I Y G P   + +F  +    ++ V++T+++ +  +  LL              G L      W Y+++DEGH ++N   K+   + TR  C R RL++TGTP+QN++ ELW+L +FL+P +  +C+ F + +        + +G KV+   E   L +  LH+ + PF+LRR+K +V  ELP K+     C MS LQ  LY H  +           L+D   K N+     R+   TM +LR +CNHP L   +     R     R ++A    +D   +SGKL  L +++                       +R+L+F Q   MM +V+  +        +LRLDGS    +R  +++KF+  ++   + +L+T  GGLGLNL +A+ VI  + DWNP +D+QA DRAHRIGQK  V V+RLITA S+EEKI+    +K  +   V+   K +N+        ILE
Sbjct: 1198 SLKLKPYQIKGLEWMVSLFNNNLNGILADEMGLGKTIQTIAFIT-YLMEIKKTSGPFLVIVPLSTVPNWQNEFDKWAANV---HLIAYKG-PKETRKVFEPIIKSGKFNVLLTTFEYVIREKALL--------------GKLR-----WKYMIIDEGHRLKNQHCKLTEMLNTRFQCQR-RLLITGTPLQNKLPELWALLNFLLPSIFSSCSTFEQWFNAPF----ATTGEKVELTQEETMLIIRRLHKVLRPFLLRRLKKEVESELPDKMEFVVRCDMSALQKVLYKHMQKGL---------LLDG--KTNTGSKSLRN---TMIHLRKLCNHPFL-FENVEESCRNFWDARFISA----VDLYRVSGKLELLSRILPKL----------------QATGHRVLMFFQMTSMMTIVEDFLAGGT--IQYLRLDGSTKPDERGALLDKFNAPNSEYFLFMLSTRAGGLGLNLQTADTVIIFDSDWNPHQDMQAQDRAHRIGQKAEVRVFRLITANSVEEKILAAARYKLNVDEKVIQAGKFDNRSTGAERREILE 1686          

Query: 3686 LRQYQEEGVNWLGFLNRYGLHGVLADDMGLGKTLQAICVIAGEYSRAPSTCPPSLIVCPPTLTVHWHQEFKKFLVNLPDFNTIVYLGTPMYRQCIFNSLSR--YQVVITSYDTLRSDMNLLARPTFPRCGTDVTKGSLMANSNVWNYVVLDEGHLIRNYKSKVAVATRALC-ARHRLVLTGTPIQNRVGELWSLFDFLMPGLLGTCTEFNRRYGRVLEQNGSNSGRKVD--SEAGTLALELLHRQVLPFMLRRVKDDVLQELPPKIMQDYMCTMSPLQLRLYTHCMESQAATDTDFVELVDKSYKENSAINQHRHGFQTMHYLRLVCNHPSLGLTSSHPLYRTLMRELAANNQC--LDDINLSGKLVALRQLILDCGVGVSGAGEEELDETSVVASNRLLVFCQSIKMMELVDKMIRNEIPKATHLRLDGSVPAKDRQQIVEKFSC-DAXXXXXXXXXXXXXXXXXXXXANIVIFVEHDWNPMRDLQAMDRAHRIGQKHTVIVYRLITAQSIEEKIMNLQEFK 5230
            L+ YQ +G+ W+  L    L+G+LAD+MGLGKT+Q I ++            P L++ P +   +W  EF K+    P   TI+Y GT   R+ +   + +  + V++T+Y+ +  +  LL +                     W Y+++DEGH ++N+  K+ +       A+HRL+LTGTP+QN++ ELW+L +FL+P +  +C  F + +        + +G KV+   E   L +  LH+ + PF+LRR+K +V  +LP K      C  S LQ  +Y H  +           L+D      +     R    T+ +LR +CNHP L      P      R     N+    D + ++GKL  L +++    +  +G              +R+L+F Q   MM + +  +     + T+LRLDGS    +R  ++ +F+  ++ + + +L+T  GGLGLNL +A+ VI  + DWNP +D+QA DRAHRIGQK  V V RLITA S+EEKI+    +K
Sbjct:  533 LKPYQIKGLEWMVSLYNNNLNGILADEMGLGKTIQTISLVTY-LMEVKQNNGPYLVIVPLSTLSNWQNEFAKWA---PSVTTIIYKGTKDARRRVEGQIRKGAFNVLMTTYEYVIKEKALLGKIR-------------------WKYMIIDEGHRLKNHNCKLTLMLNGFFHAQHRLLLTGTPLQNKLPELWALLNFLLPSIFSSCGTFEQWFNAPF----ATTGEKVELNQEETMLIIRRLHKVLRPFLLRRLKKEVESQLPDKTEYVIKCDQSALQKVIYRHMQKGL---------LLDAKMSSGA-----RSLMNTVVHLRKLCNHPFL-----FPNIEDSCRAYWKVNEVNGTDLMRVAGKLELLDRIL--PKLKATG--------------HRILMFFQMTSMMNIFEDFLN--FRRYTYLRLDGSTKPDERGDLLTQFNAPNSDLFLFMLSTRAGGLGLNLQTADTVIIFDSDWNPHQDMQAQDRAHRIGQKKEVRVLRLITANSVEEKILAAARYK 991          

Query: 3683 KLRQYQEEGVNWLGFLNRYGLHGVLADDMGLGKTLQAICVIAGEYSRAPSTCPPSLIVCPPTLTVHWHQEFKKFLVNLPDFNTIVYLGTPMYRQCIFN--------SLSRYQVVITSYDTLRSDMNLLARPTFPRCGTDVTKGSLMANSNVWNYVVLDEGHLIRNYKSKVAVATRALCARHRLVLTGTPIQNRVGELWSLFDFLMPGLLGTCTEFNRRYGRVLEQNGSNSGRKVDSEAGTLALELLHRQVLPFMLRRVKDDVLQELPPKIMQDYMCTMSPLQLRLYTHCMESQAATDTDFVELVDKSYKE-NSAINQHRHGFQTM-HYLRLVCNHPSLGLTSSHPLYRTLMRELAANNQCLDDINLSGKLVALRQLILDCGVGVSGAGEEELDETSVVASNRLLVFCQSIKMMELVDKMIRNEIPKATHLRLDGSVPAKDRQQIVEKFSC-DAXXXXXXXXXXXXXXXXXXXXANIVIFVEHDWNPMRDLQAMDRAHRIGQKHTVIVYRLITAQSIEEKIMNLQEFKKFLANAVVSK 5260
            KLR YQ EG+NW+ +    G   +LAD+MGLGKT+Q+I ++A  + R      P L+V P +    W +EF ++    P+ N +VY+G  + R  I             +   ++T+Y+ L  D   L+                   S  W  +++DE H ++N +S +  +       H+L++TGTP+QN + ELW+L  F+MP       EF   +                +E+    +  LH+++ PF+LRRVK DV + LPPK  Q     M+  Q + Y                ++ K+Y+E +  +    +GF  +   L+  CNH SL     H +Y      L    Q L  +  SGKL+ L +L+  C +   G              +R+L+F Q + M++++ + +  ++ +    RLDGS+ A  R+Q ++ ++   ++    LL+T  GGLG+NL +A+ VI  + DWNP  DLQAM RAHRIGQ  TV +YRL+T  S+EE+I+   + K  L + V+ +
Sbjct:  404 KLRDYQLEGLNWMVYAWCKGNSSILADEMGLGKTIQSISLLASLFHRY-DLAGPYLVVVPLSTMAAWQKEFAQWA---PEMNLVVYMGDVVSRDMIRQYEWFVGGTKKMKINAILTTYEILLKDKAFLS-------------------SIDWAALLVDEAHRLKNDESLLYKSLTQFRFNHKLLITGTPLQNSLKELWALLHFIMPEKFDCWEEFETAH----------------NESNHKGISALHKKLEPFLLRRVKKDVEKSLPPKTEQILRVDMTAHQKQFYKW--------------ILTKNYRELSKGVKGSINGFVNLVMELKKCCNHASLTRQYDH-IYDDAQGRL----QQL--LKSSGKLILLDKLL--CRLKDKG--------------HRVLIFSQMVMMLDILQEYL--QLRRFPSQRLDGSMRADLRKQALDHYNAPGSTDFAFLLSTRAGGLGINLATADTVIIFDSDWNPQNDLQAMSRAHRIGQTKTVNIYRLVTKGSVEEEIVERAKRKLVLDHLVIQR 862          

Query: 3374 GAIELIYLVCHS---GLLPYRLAIAVIILPVVLACLNAPFDPLRRVATHVFSXXXXXXXXESSGADLSILTPARQQQRKQHLSFLDSLLNPKLIGQYNAHHSVVSAKLRQYQEEGVNWLGFLNRYGLHGVLADDMGLGKTLQAICVIAGEY---SRAPSTCPPSLIVCPPTLTVHWHQEFKKFLVNLPDFNTIVYLGTPMYRQCIFNSL-SRYQVVITSYDTLRSDMNLLARPTFPRCGTDVTKGSLMANSNVWNYVVLDEGHLIRNYKSKVAVATRALCARHRLVLTGTPIQNRVGELWSLFDFLMPGLLGTCTEFNRRYGR-VLEQNGSNSGRKVDSEAGTLALELLHRQVLPFMLRRVKDDVLQELPPKIMQDYMCTMSPLQLRLYTHCMESQAATDTDFVELVDKSYKENSA------INQHRHGFQTMHYLRLVCNHPSLGLTSSHPLYRTLMRELAANNQCLDDINLSGKLVALRQLILDCGVGVSGAGEEELDETSVVASNRLLVFCQSIKMMELVDK-MIRNEIPKATHLRLDGSVPAKDRQQIVEKFSCDAXXXXXXXXXXXXXXXXXXXXANIVIFVEHDWNPMRDLQAMDRAHRIGQKHTVIVYRLITAQSIEEKIMNLQEFKKFLANAVVSKDNNQMASMNTENILEIMNKEANWPTQSPPASANGKQKVVSSVSGGTETQLGSKSVLSKISKADSGERVYDCLDEYDQEYNLDSFV 5515
            GAIE I  V       ++PY   I ++++P+ L  ++ P + +R ++TH F+ L+ L+PL+     L   +   Q ++ +   FLD L NPK I  Y     + S +LR YQ+ G+NWL FLN+Y LHG+L DDMGLGKTLQ IC++AG++     A     PSL++CPPTLT HW  E +KFL        + Y G P+ R+ + + + ++  +V+ SYDT+R D++  +   F                   NY VLDEGH+I+N K+K + A + L A HRL+L+GTPIQN V ELWSLFDFLMPG LGT  +F +R+ R +L    + S  K + EAG LA+E LHRQVLPF+LRRVK+DVL++LPPKI QD +C +SPLQLRLY      +  ++    + +DK    +SA      ++   H FQ + YL+ VCNHP L L  S  L + +  +LA +N  LDDI  S KL AL+QL+LDCG+GV         +T  V+ +R L+FCQ   M+++V++ ++R  +P  T+LRLDGSVPA  RQ IV  F+ D SID+LLLTT +GGLGLNLT A+ VIFVEHDWNPM+DLQAMDRAHRIGQK  V VYRLIT  S+EEKIM LQ+FK   AN VVS +N  + +M T  I ++ N   +   +S      G   V  + SGG    +   +++  + +  S         +Y++EY+L +FV
Sbjct: 1250 GAIEAIERVVSRLQIKVVPY---IVLLVVPL-LGAMSDPDESVRLLSTHCFANLVQLMPLDGKTEQLK--SDPLQARKTRDREFLDYLFNPKSIPNYKVPVPI-SVELRCYQQAGINWLWFLNKYNLHGILCDDMGLGKTLQTICILAGDHMHRQTANLANLPSLVICPPTLTGHWVYEVEKFLDQGSVLRPLHYYGFPVGREKLRSDIGTKCNLVVASYDTVRKDIDFFSGIHF-------------------NYCVLDEGHIIKNGKTKSSKAIKRLKANHRLILSGTPIQNNVLELWSLFDFLMPGFLGTEKQFVQRFSRPILSSRDAKSSAK-EQEAGVLAMEALHRQVLPFLLRRVKEDVLKDLPPKITQDLLCELSPLQLRLY------EDFSNKHLKDCLDKLGDSSSASMVTENLSAKTHIFQALRYLQNVCNHPKLVLRQSEELTK-VTSQLALSNSSLDDIEHSAKLPALKQLLLDCGIGV---------QTESVSQHRALIFCQLKAMLDIVEQDLLRRHLPSVTYLRLDGSVPASQRQDIVNNFNSDPSIDVLLLTTMVGGLGLNLTGADTVIFVEHDWNPMKDLQAMDRAHRIGQKKVVNVYRLITRNSLEEKIMGLQKFKILTANTVVSAENASLQTMGTSQIFDLFNGGKDKGAES------GSSAVQGTASGG----MSMNTIIENLPELWSEH-------QYEEEYDLGNFV 1918          

Query:  725 WPWVDFCEELLKNLWDAKWEIRHGAATCLRELI--RSQGSIMLPKNANISSTDKFAACHERFQEEIVVRLLCTLTLDQLSDFVSDEMVAPVRESCAQALGVISVHLTRRLVEILANQLLSLLNH-DEWRVNHXXXXXXXXXXXXRMDLVEVLLP 1177
            WP  +FC  L  +L+ AKWE+RHGAAT LRELI   +QG+      A + + ++    H R+ E+  +RLLC L LD+  DFVSD++VAPVRE+CAQ LG +   +    V+ + N LL L+ H +EW V HG LLGLKY+   R +L+ + LP
Sbjct:  324 WPLENFCSRLFIDLFHAKWEVRHGAATALRELINQHAQGA----GKAVLQTREQMDEAHSRWLEDAALRLLCVLCLDRFGDFVSDQVVAPVRETCAQVLGTLVKEMEASKVQRIVNILLQLIQHKNEWDVRHGGLLGLKYVFVVREELLPIYLP 473          

Query: 3374 GAIELIYLVCHS---GLLPYRLAIAVIILPVVLACLNAPFDPLRRVATHVFSXXXXXXXXESSGADLSILTPARQQQRKQHLSFLDSLLNPKLIGQYNAHHSVVSAKLRQYQEEGVNWLGFLNRYGLHGVLADDMGLGKTLQAICVIAGEY---SRAPSTCPPSLIVCPPTLTVHWHQEFKKFLVNLPDFNTIVYLGTPMYRQCIFNSL-SRYQVVITSYDTLRSDMNLLARPTFPRCGTDVTKGSLMANSNVWNYVVLDEGHLIRNYKSKVAVATRALCARHRLVLTGTPIQNRVGELWSLFDFLMPGLLGTCTEFNRRYGR-VLEQNGSNSGRKVDSEAGTLALELLHRQVLPFMLRRVKDDVLQELPPKIMQDYMCTMSPLQLRLYTHCMESQAATDTDFVELVDKSYKENSA------INQHRHGFQTMHYLRLVCNHPSLGLTSSHPLYRTLMRELAANNQCLDDINLSGKLVALRQLILDCGVGVSGAGEEELDETSVVASNRLLVFCQSIKMMELVDK-MIRNEIPKATHLRLDGSVPAKDRQQIVEKFSCDAXXXXXXXXXXXXXXXXXXXXANIVIFVEHDWNPMRDLQAMDRAHRIGQKHTVIVYRLITAQSIEEKIMNLQEFKKFLANAVVSKDNNQMASMNTENILEIMNKEANWPTQSPPASANGKQKVVSSVSGGTETQLGSKSVLSKISKADSGERVYDCLDEYDQEYNLDSFV 5515
            GAIE I  V       ++PY   I ++++P+ L  ++ P + +R ++TH F+ L+ L+PL+     L   +   Q ++ +   FLD L NPK I  Y     + S +LR YQ+ G+NWL FLN+Y LHG+L DDMGLGKTLQ IC++AG++     A     PSL++CPPTLT HW  E +KFL        + Y G P+ R+ + + + ++  +V+ SYDT+R D++  +   F                   NY VLDEGH+I+N K+K + A + L A HRL+L+GTPIQN V ELWSLFDFLMPG LGT  +F +R+ R +L    + S  K + EAG LA+E LHRQVLPF+LRRVK+DVL++LPPKI QD +C +SPLQLRLY      +  ++    + +DK    +SA      ++   H FQ + YL+ VCNHP L L  S  L + +  +LA +N  LDDI  S KL AL+QL+LDCG+GV         +T  V+ +R L+FCQ   M+++V++ ++R  +P  T+LRLDGSVPA  RQ IV  F+ D SID+LLLTT +GGLGLNLT A+ VIFVEHDWNPM+DLQAMDRAHRIGQK  V VYRLIT  S+EEKIM LQ+FK   AN VVS +N  + +M T  I ++ N   +   +S      G   V  + SGG    +   +++  + +  S         +Y++EY+L +FV
Sbjct: 1250 GAIEAIERVVSRLQIKVVPY---IVLLVVPL-LGAMSDPDESVRLLSTHCFANLVQLMPLDGKTEQLK--SDPLQARKTRDREFLDYLFNPKSIPNYKVPVPI-SVELRCYQQAGINWLWFLNKYNLHGILCDDMGLGKTLQTICILAGDHMHRQTANLANLPSLVICPPTLTGHWVYEVEKFLDQGSVLRPLHYYGFPVGREKLRSDIGTKCNLVVASYDTVRKDIDFFSGIHF-------------------NYCVLDEGHIIKNGKTKSSKAIKRLKANHRLILSGTPIQNNVLELWSLFDFLMPGFLGTEKQFVQRFSRPILSSRDAKSSAK-EQEAGVLAMEALHRQVLPFLLRRVKEDVLKDLPPKITQDLLCELSPLQLRLY------EDFSNKHLKDCLDKLGDSSSASMVTENLSAKTHIFQALRYLQNVCNHPKLVLRQSEELTK-VTSQLALSNSSLDDIEHSAKLPALKQLLLDCGIGV---------QTESVSQHRALIFCQLKAMLDIVEQDLLRRHLPSVTYLRLDGSVPASQRQDIVNNFNSDPSIDVLLLTTMVGGLGLNLTGADTVIFVEHDWNPMKDLQAMDRAHRIGQKKVVNVYRLITRNSLEEKIMGLQKFKILTANTVVSAENASLQTMGTSQIFDLFNGGKDKGAES------GSSAVQGTASGG----MSMNTIIENLPELWSEH-------QYEEEYDLGNFV 1918          

Query:  725 WPWVDFCEELLKNLWDAKWEIRHGAATCLRELI--RSQGSIMLPKNANISSTDKFAACHERFQEEIVVRLLCTLTLDQLSDFVSDEMVAPVRESCAQALGVISVHLTRRLVEILANQLLSLLNH-DEWRVNHXXXXXXXXXXXXRMDLVEVLLP 1177
            WP  +FC  L  +L+ AKWE+RHGAAT LRELI   +QG+      A + + ++    H R+ E+  +RLLC L LD+  DFVSD++VAPVRE+CAQ LG +   +    V+ + N LL L+ H +EW V HG LLGLKY+   R +L+ + LP
Sbjct:  324 WPLENFCSRLFIDLFHAKWEVRHGAATALRELINQHAQGA----GKAVLQTREQMDEAHSRWLEDAALRLLCVLCLDRFGDFVSDQVVAPVRETCAQVLGTLVKEMEASKVQRIVNILLQLIQHKNEWDVRHGGLLGLKYVFVVREELLPIYLP 473          

Query: 3671 VVSAKLRQYQEEGVNWLGFLNRYGLHGVLADDMGLGKTLQAICVIAGEYSRAPSTCPPSLIVCPPTLTVHWHQEFKKFLVNLPDFNTIVYLGTPMYRQCIFNSL--SRYQVVITSYDTLRSDMNLLARPTFPRCGTDVTKGSLMANSNVWNYVVLDEGHLIRNYKSKVA-VATRALCARHRLVLTGTPIQNRVGELWSLFDFLMPGLLGTCTEFNRRYGRVLEQNGSNSGRKVD--SEAGTLALELLHRQVLPFMLRRVKDDVLQELPPKIMQDYMCTMSPLQLRLYTHCMESQAATDTDFVELVDKSYKENSAINQHRHGFQTMHYLRLVCNHPSL---------------GLTSSHPLYRTLMRELAANNQCLDDINLSGKLVALRQLILDCGVGVSGAGEEELDETSVVASN-RLLVFCQSIKMMELVDKMIRNEIPKATHLRLDGSVPAKDRQQIVEKFSCDAXXX-XXXXXXXXXXXXXXXXXANIVIFVEHDWNPMRDLQAMDRAHRIGQKHTVIVYRLITAQSIEEKIMNLQEFKKFLANAVV 5254
            +V+  L++YQ +G+ WL  L    L+G+LAD+MGLGKT+Q I ++     R      P LI+ P +   +W  EF+K+    P    + Y G+P  R+ + N +  +++ V++T+Y+ +  D  +LA+                     W Y+++DEGH ++N+  K+  V      A +RL+LTGTP+QN++ ELW+L +FL+P +  +C+ F + +        + +G KV+   E   L +  LH+ + PF+LRR+K +V  +LP K+     C MS LQ  LY H M+S+    TD  E          A+        T+  LR +CNHP +               G+ S   LYR                 +SGK   L +++                   + A+N R+L+FCQ  + M +++  +     +  +LRLDG+  A+DR +++ KF+   S   + LL+T  GGLGLNL +A+ V+  + DWNP +DLQA DRAHRIGQ++ V V RL+T  S+EE+I+    +K  +   V+
Sbjct:  772 MVNGTLKEYQIKGLEWLVSLYNNNLNGILADEMGLGKTIQTISLVTYLMDRK-KVMGPYLIIVPLSTLPNWVLEFEKW---APAVGVVSYKGSPQGRRLLQNQMRATKFNVLLTTYEYVIKDKAVLAKIQ-------------------WKYMIIDEGHRMKNHHCKLTQVLNTHYIAPYRLLLTGTPLQNKLPELWALLNFLLPSIFKSCSTFEQWFNAPF----ATTGEKVELNEEETILIIRRLHKVLRPFLLRRLKKEVEHQLPDKVEYIIKCDMSALQRVLYKH-MQSKGVLLTDGSEKGKHGKGGAKAL------MNTIVQLRKLCNHPFMFQHIEEKYCDHTGGHGVVSGPDLYR-----------------VSGKFELLDRIL-----------------PKLKATNHRVLLFCQMTQCMTIIEDYLGWR--QFGYLRLDGTTKAEDRGELLRKFNAKGSDVFVFLLSTRAGGLGLNLQTADTVVIFDSDWNPHQDLQAQDRAHRIGQRNEVRVLRLMTVNSVEERILAAARYKLNMDEKVI 1251          

Query: 3671 VVSAKLRQYQEEGVNWLGFLNRYGLHGVLADDMGLGKTLQAICVIAGEYSRAPSTCPPSLIVCPPTLTVHWHQEFKKFLVNLPDFNTIVYLGTPMYRQCIFNSL--SRYQVVITSYDTLRSDMNLLARPTFPRCGTDVTKGSLMANSNVWNYVVLDEGHLIRNYKSKVA-VATRALCARHRLVLTGTPIQNRVGELWSLFDFLMPGLLGTCTEFNRRYGRVLEQNGSNSGRKVD--SEAGTLALELLHRQVLPFMLRRVKDDVLQELPPKIMQDYMCTMSPLQLRLYTHCMESQAATDTDFVELVDKSYKENSAINQHRHGFQTMHYLRLVCNHPSL---------------GLTSSHPLYRTLMRELAANNQCLDDINLSGKLVALRQLILDCGVGVSGAGEEELDETSVVASN-RLLVFCQSIKMMELVDKMIRNEIPKATHLRLDGSVPAKDRQQIVEKFSCDAXXX-XXXXXXXXXXXXXXXXXANIVIFVEHDWNPMRDLQAMDRAHRIGQKHTVIVYRLITAQSIEEKIMNLQEFKKFLANAVV 5254
            +V+  L++YQ +G+ WL  L    L+G+LAD+MGLGKT+Q I ++     R      P LI+ P +   +W  EF+K+    P    + Y G+P  R+ + N +  +++ V++T+Y+ +  D  +LA+                     W Y+++DEGH ++N+  K+  V      A +RL+LTGTP+QN++ ELW+L +FL+P +  +C+ F + +        + +G KV+   E   L +  LH+ + PF+LRR+K +V  +LP K+     C MS LQ  LY H M+S+    TD  E          A+        T+  LR +CNHP +               G+ S   LYR                 +SGK   L +++                   + A+N R+L+FCQ  + M +++  +     +  +LRLDG+  A+DR +++ KF+   S   + LL+T  GGLGLNL +A+ V+  + DWNP +DLQA DRAHRIGQ++ V V RL+T  S+EE+I+    +K  +   V+
Sbjct:  768 MVNGTLKEYQIKGLEWLVSLYNNNLNGILADEMGLGKTIQTISLVTYLMDRK-KVMGPYLIIVPLSTLPNWVLEFEKW---APAVGVVSYKGSPQGRRLLQNQMRATKFNVLLTTYEYVIKDKAVLAKIQ-------------------WKYMIIDEGHRMKNHHCKLTQVLNTHYIAPYRLLLTGTPLQNKLPELWALLNFLLPSIFKSCSTFEQWFNAPF----ATTGEKVELNEEETILIIRRLHKVLRPFLLRRLKKEVEHQLPDKVEYIIKCDMSALQRVLYKH-MQSKGVLLTDGSEKGKHGKGGAKAL------MNTIVQLRKLCNHPFMFQHIEEKYCDHTGGHGVVSGPDLYR-----------------VSGKFELLDRIL-----------------PKLKATNHRVLLFCQMTQCMTIIEDYLGWR--QFGYLRLDGTTKAEDRGELLRKFNAKGSDVFVFLLSTRAGGLGLNLQTADTVVIFDSDWNPHQDLQAQDRAHRIGQRNEVRVLRLMTVNSVEERILAAARYKLNMDEKVI 1247          

Query: 3671 VVSAKLRQYQEEGVNWLGFLNRYGLHGVLADDMGLGKTLQAICVIAGEYSRAPSTCPPSLIVCPPTLTVHWHQEFKKFLVNLPDFNTIVYLGTPMYRQCIFNSL--SRYQVVITSYDTLRSDMNLLARPTFPRCGTDVTKGSLMANSNVWNYVVLDEGHLIRNYKSKVA-VATRALCARHRLVLTGTPIQNRVGELWSLFDFLMPGLLGTCTEFNRRYGRVLEQNGSNSGRKVD--SEAGTLALELLHRQVLPFMLRRVKDDVLQELPPKIMQDYMCTMSPLQLRLYTHCMESQAATDTDFVELVDKSYKENSAINQHRHGFQTMHYLRLVCNHPSL---------------GLTSSHPLYRTLMRELAANNQCLDDINLSGKLVALRQLILDCGVGVSGAGEEELDETSVVASN-RLLVFCQSIKMMELVDKMIRNEIPKATHLRLDGSVPAKDRQQIVEKFSCDAXXX-XXXXXXXXXXXXXXXXXANIVIFVEHDWNPMRDLQAMDRAHRIGQKHTVIVYRLITAQSIEEKIMNLQEFKKFLANAVV 5254
            +V+  L++YQ +G+ WL  L    L+G+LAD+MGLGKT+Q I ++     R      P LI+ P +   +W  EF+K+    P    + Y G+P  R+ + N +  +++ V++T+Y+ +  D  +LA+                     W Y+++DEGH ++N+  K+  V      A +RL+LTGTP+QN++ ELW+L +FL+P +  +C+ F + +        + +G KV+   E   L +  LH+ + PF+LRR+K +V  +LP K+     C MS LQ  LY H M+S+    TD  E          A+        T+  LR +CNHP +               G+ S   LYR                 +SGK   L +++                   + A+N R+L+FCQ  + M +++  +     +  +LRLDG+  A+DR +++ KF+   S   + LL+T  GGLGLNL +A+ V+  + DWNP +DLQA DRAHRIGQ++ V V RL+T  S+EE+I+    +K  +   V+
Sbjct:  768 MVNGTLKEYQIKGLEWLVSLYNNNLNGILADEMGLGKTIQTISLVTYLMDRK-KVMGPYLIIVPLSTLPNWVLEFEKW---APAVGVVSYKGSPQGRRLLQNQMRATKFNVLLTTYEYVIKDKAVLAKIQ-------------------WKYMIIDEGHRMKNHHCKLTQVLNTHYIAPYRLLLTGTPLQNKLPELWALLNFLLPSIFKSCSTFEQWFNAPF----ATTGEKVELNEEETILIIRRLHKVLRPFLLRRLKKEVEHQLPDKVEYIIKCDMSALQRVLYKH-MQSKGVLLTDGSEKGKHGKGGAKAL------MNTIVQLRKLCNHPFMFQHIEEKYCDHTGGHGVVSGPDLYR-----------------VSGKFELLDRIL-----------------PKLKATNHRVLLFCQMTQCMTIIEDYLGWR--QFGYLRLDGTTKAEDRGELLRKFNAKGSDVFVFLLSTRAGGLGLNLQTADTVVIFDSDWNPHQDLQAQDRAHRIGQRNEVRVLRLMTVNSVEERILAAARYKLNMDEKVI 1247          

Query: 3374 GAIELIYLVCHS---GLLPYRLAIAVIILPVVLACLNAPFDPLRRVATHVFSXXXXXXXXESSGADLSILTP--ARQQQRKQHLSFLDSLLNPKLIGQYNAHHSVVSAKLRQYQEEGVNWLGFLNRYGLHGVLADDMGLGKTLQAICVIAG-------EYSR--APSTCP-PSLIVCPPTLTVHWHQEFKKFLVNLPDFNTIVYLGTPMYRQCIFNSLSRYQVVITSYDTLRSDMNLLARPTFPRCGTDVTKGSLMANSNVWNYVVLDEGHLIRNYKSKVAVATRALCARHRLVLTGTPIQNRVGELWSLFDFLMPGLLGTCTEFNRRYGRVLEQNGSNSGRKVDSEAGTLALELLHRQVLPFMLRRVKDDVLQELPPKIMQDYMCTMSPLQLRLYTHCMESQAATDTDFV--ELVDKSYKENSAINQHRHGFQTMHYLRLVCNHPSLGLTSSHPLYRTLMRELAANNQCLDDINLSGKLVALRQLILDCGVGVSGAGEEELDETSVVASNRLLVFCQSIKMMELVDK-MIRNEIPKATHLRLDGSVPAKDRQQIVEKFSCDAXXXXXXXXXXXXXXXXXXXXANIVIFVEHDWNPMRDLQAMDRAHRIGQKHTVIVYRLITAQSIEEKIMNLQEFKKFLANAVVSKDNNQMASMNTENILEIMN 5314
            GAIE +  V       ++PY   I ++++PV L  ++ P D +R +AT  F+ L+ LLPLE+   D   ++    RQ+ R++H  FL+ LL+ + +  Y     +  A+LR+YQ++GVNWL FLN+Y LHG+L DDMGLGKTLQ+IC++AG       EY+R  AP +CP PS++VCPPTLT HW  E  KF  +    N + Y G P  R  + + + ++ +++ SYD +R+D+       F                   NY +LDEGH+I+N K+K++ A + L A +RL+L+GTPIQN V ELWSLFDFLMPG LGT  +F  RYG+ +  +        + EAG LA+E LHRQVLPF+LRR+KDDVLQ+LPPKI+QDY C +SPLQ++LY    +S+A  + D V      +  +E   +    H FQ + YLR +CNHP+L LT  HP Y+ +  +L+  +  L DI  + KL AL+QL+LDCG+G +GA +   +  +VVA +R+L+FCQ   M+++V++ +++ ++P  T+LRLDGSV A  R  IV +F+ D SID+LLLTT +GGLGLNLT A+ V+FVEHDWNPMRDLQAMDRAHRIGQK  V VYRLIT  ++EEKIM LQ+FK  +AN V+S++N  + SM TE +L +  
Sbjct: 1170 GAIEALACVMEQLDVDIVPY---IVLLVVPV-LGRMSDPCDSVRFMATQCFATLIRLLPLEAGIPDPPSMSEDLIRQKARERH--FLEQLLDGRKLENYKIPVPI-KAELRKYQQDGVNWLAFLNKYKLHGILCDDMGLGKTLQSICILAGDHFLRAQEYTRTKAPDSCPLPSIVVCPPTLTGHWVDEVGKF-CSKEFLNPLHYTGPPTERARLQHQVKKHNLIVASYDVVRNDVEFFRDIKF-------------------NYCILDEGHVIKNGKTKLSKAIKQLTANYRLILSGTPIQNNVLELWSLFDFLMPGFLGTERQFAARYGKPILASRDAKSSSREQEAGVLAMEALHRQVLPFLLRRMKDDVLQDLPPKIIQDYYCNLSPLQVQLYEDFAKSRAKVNVDDVISTASTQEDEEKPKLKATGHVFQALQYLRKLCNHPALVLTPQHPEYKHITEQLSTQHSSLRDIQHAPKLSALKQLLLDCGLGSAGASDSGTE--AVVAQHRVLIFCQLKSMLDIVEQDLLKPQLPGVTYLRLDGSVQAGLRHSIVSRFNNDPSIDVLLLTTHVGGLGLNLTGADTVVFVEHDWNPMRDLQAMDRAHRIGQKRVVNVYRLITRGTLEEKIMGLQKFKMTIANTVISQENASLQSMGTEQLLNLFT 1805          

Query:   89 RLDKLFELLESNHQNI-RNAAAIQIGQLSANNQVNISALLAKLLPYAKHKIWVVRIAASDAVRHIGNNAKLWVPGTSESNVTNVSNL---------INLENLNLHDILKIGTRLYSRDFKDLD-------EANTNQNI--NRDELARHLGFLIPDEC--EIKNLITVKDCELVESKSENKMS-------------------VELAVMKSMENSPKKPVKR-----PHEEVQDVN-----------EPGTKMK-----CVEKIGNETE------------RERNTEWPWVDFCEELLKNLWDAKWEIRHGAATCLRELIRSQGSIMLPKNANISST-DKFAACHERFQEEIVVRLLCTLTLDQLSDFVSDEMVAPVRESCAQALGVISVHLTRRLVEILANQLLSLLNHDEWRVNHXXXXXXXXXXXXRMDLVEVLLPIIYDPISSHLKGNXXXXXXXXXXXXLMPLFGDCCSNTVAISNEELDTLKTDLWDVLAVRIDCTTSGATCAVLQLLERLYEKCNVVYNQSEDQPMATDRVKALNEYINRLHWCYFNYS-DLVRLAAVRTCRAVL----QSIGIKVGTILEHGTIXXXXXXXXXXXXIDDNCQVAAEAHSVWNQFIDSLPEQLLARVSCERLEIWMCSAMQPARLSYTPGSILMPDYIIXXXXXXXXXXXXDGLDEDDGNKHHILTEFYIGGRESFITDGSSAARDDLVXXXXXXXXXXXXXXXXXFI---FHEAGIRNILISIIAQI---HLKDRLAVQRFVASMILAYWDPDHLLAMRNLNDCSL--SPLQSQLLTALEEPIYYQEILSQFKQMHKACRDLILIYIEREI 2338
            RL++LF LL++    + R AAA Q+G +   +   ++ LL+K+L Y +   W  RIAA  AV  I  N   W P     +     +L         ++    ++  +LK G  L      + +       E +  + +   R +L + LG  +      + + L   +D E   + S N+                     ++      M N  K   KR       +  +DV+           EP  K +      +E+  N+++             E   EWP   FC+EL  +L++  WEIRHGA T LRE+++  G+        + ST ++    H+ + E++V+RLLC   LD+  DFVSDE+VAPVRE+CAQ LGV   H+    V +  + LL LL  D+W V HG LLG+KY LA R DL+  LLP +   I+  L+ + DDDVR  A AAL+P+        V +   ++  +   LW+ L    D T S  T +++ LL  L     V   Q   Q       ++L   + R+ W +  ++   VR AA+ T   +L    QS  + +  I++      +L  + Q  +++ N ++      VW + +   P+Q +   SC  +  W+C  MQ   +   P  +L         A   A      + E          + YIGG E+   +   A RD +V RARL A +LL  LC        + + +       +AQ+   HL  + A+QR   SM++  W            +C L  S +Q +LL  L E +YY EI   F +M   C+ LI +  +  I
Sbjct:    1 RLERLFILLDTGTTPVTRKAAAQQLGDVVKLHPHELNNLLSKVLTYLRSPNWDTRIAAGQAVEAIVKNIPEWNPSPKPKDEVCAEDLSPEDVSTDRLSFYRFDISRLLKHGASLLGSAGAEFELQDDKSGETDPKERLARQRKQLQKKLGLDMGAAIGMDTEELFNDEDLEDACASSTNRTQPGKSLGCHFSRNHLPAAELIDSEFRPGMSNRQKNKAKRMAKLVAKQRSRDVDSNEKSNDSFEGEPEEKRRKTTNVVIEQPANDSKVLIDNVPDNSSLFEETQEWPLESFCDELCNDLFNPSWEIRHGAGTGLREVLKCHGA---GGGKTVGSTAEQMERQHQEWLEDLVIRLLCVFALDRFGDFVSDEVVAPVRETCAQTLGVALRHMENSGVAMTVDILLKLLTEDQWEVRHGGLLGIKYALAVRQDLIAELLPRVLPAITEGLR-DLDDDVRAVAAAALIPVV----DGLVQLQPAKVPFIVDTLWNALLELDDLTAS--TNSIMTLLSSLLTYPQV--RQCSTQ-------QSLTVLVPRV-WPFLRHTIASVRRAALDTLFTLLSKADQSCAVWLNPIMQD-----MLRHIFQSCILESNQEILELIQKVWRELLRQAPQQYVVAASCPWMGAWLCLMMQAPHIPIDPNMLLEVKARFKEKAAGKARQGSVPVKET--------VQEYIGGAETVTEE--PATRDYVVTRARLMAAKLLGALCSCICDPRLNSSSLELRPAESLAQLLLFHLNSKSALQRIAVSMVICEWAGLQ-------KECELLSSVVQPRLLVILSEQLYYDEIAIPFTRMQNECKQLIALLADAHI 795          

Query: 3374 GAIELIYLVCHS---GLLPYRLAIAVIILPVVLACLNAPFDPLRRVATHVFSXXXXXXXXESSGADLSILTP--ARQQQRKQHLSFLDSLLNPKLIGQYNAHHSVVSAKLRQYQEEGVNWLGFLNRYGLHGVLADDMGLGKTLQAICVIAG-------EYSR--APSTCP-PSLIVCPPTLTVHWHQEFKKFLVNLPDFNTIVYLGTPMYRQCIFNSLSRYQVVITSYDTLRSDMNLLARPTFPRCGTDVTKGSLMANSNVWNYVVLDEGHLIRNYKSKVAVATRALCARHRLVLTGTPIQNRVGELWSLFDFLMPGLLGTCTEFNRRYGRVLEQNGSNSGRKVDSEAGTLALELLHRQVLPFMLRRVKDDVLQELPPKIMQDYMCTMSPLQLRLYTHCMESQAATDTDFV--ELVDKSYKENSAINQHRHGFQTMHYLRLVCNHPSLGLTSSHPLYRTLMRELAANNQCLDDINLSGKLVALRQLILDCGVGVSGAGEEELDETSVVASNRLLVFCQSIKMMELVDK-MIRNEIPKATHLRLDGSVPAKDRQQIVEKFSCDAXXXXXXXXXXXXXXXXXXXXANIVIFVEHDWNPMRDLQAMDRAHRIGQKHTVIVYRLITAQSIEEKIMNLQEFKKFLANAVVSKDNNQMASMNTENILEIMN 5314
            GAIE +  V       ++PY   I ++++PV L  ++ P D +R +AT  F+ L+ LLPLE+   D   ++    RQ+ R++H  FL+ LL+ + +  Y     +  A+LR+YQ++GVNWL FLN+Y LHG+L DDMGLGKTLQ+IC++AG       EY+R  AP +CP PS++VCPPTLT HW  E  KF  +    N + Y G P  R  + + + ++ +++ SYD +R+D+       F                   NY +LDEGH+I+N K+K++ A + L A +RL+L+GTPIQN V ELWSLFDFLMPG LGT  +F  RYG+ +  +        + EAG LA+E LHRQVLPF+LRR+KDDVLQ+LPPKI+QDY C +SPLQ++LY    +S+A  + D V      +  +E   +    H FQ + YLR +CNHP+L LT  HP Y+ +  +L+  +  L DI  + KL AL+QL+LDCG+G +GA +   +  +VVA +R+L+FCQ   M+++V++ +++ ++P  T+LRLDGSV A  R  IV +F+ D SID+LLLTT +GGLGLNLT A+ V+FVEHDWNPMRDLQAMDRAHRIGQK  V VYRLIT  ++EEKIM LQ+FK  +AN V+S++N  + SM TE +L +  
Sbjct: 1171 GAIEALACVMEQLDVDIVPY---IVLLVVPV-LGRMSDPCDSVRFMATQCFATLIRLLPLEAGIPDPPSMSEDLIRQKARERH--FLEQLLDGRKLENYKIPVPI-KAELRKYQQDGVNWLAFLNKYKLHGILCDDMGLGKTLQSICILAGDHFLRAQEYTRTKAPDSCPLPSIVVCPPTLTGHWVDEVGKF-CSKEFLNPLHYTGPPTERARLQHQVKKHNLIVASYDVVRNDVEFFRDIKF-------------------NYCILDEGHVIKNGKTKLSKAIKQLTANYRLILSGTPIQNNVLELWSLFDFLMPGFLGTERQFAARYGKPILASRDAKSSSREQEAGVLAMEALHRQVLPFLLRRMKDDVLQDLPPKIIQDYYCNLSPLQVQLYEDFAKSRAKVNVDDVISTASTQEDEEKPKLKATGHVFQALQYLRKLCNHPALVLTPQHPEYKHITEQLSTQHSSLRDIQHAPKLSALKQLLLDCGLGSAGASDSGTE--AVVAQHRVLIFCQLKSMLDIVEQDLLKPQLPGVTYLRLDGSVQAGLRHSIVSRFNNDPSIDVLLLTTHVGGLGLNLTGADTVVFVEHDWNPMRDLQAMDRAHRIGQKRVVNVYRLITRGTLEEKIMGLQKFKMTIANTVISQENASLQSMGTEQLLNLFT 1806          

Query:   89 RLDKLFELLESNHQNI-RNAAAIQIGQLSANNQVNISALLAKLLPYAKHKIWVVRIAASDAVRHIGNNAKLWVPGTSESNVTNVSNL---------INLENLNLHDILKIGTRLYSRDFKDLD-------EANTNQNI--NRDELARHLGFLIPDEC--EIKNLITVKDCELVESKSENKMS-------------------VELAVMKSMENSPKKPVKR-----PHEEVQDVN-----------EPGTKMK-----CVEKIGNETE------------RERNTEWPWVDFCEELLKNLWDAKWEIRHGAATCLRELIRSQGSIMLPKNANISST-DKFAACHERFQEEIVVRLLCTLTLDQLSDFVSDEMVAPVRESCAQALGVISVHLTRRLVEILANQLLSLLNHDEWRVNHXXXXXXXXXXXXRMDLVEVLLPIIYDPISSHLKGNXXXXXXXXXXXXLMPLFGDCCSNTVAISNEELDTLKTDLWDVLAVRIDCTTSGATCAVLQLLERLYEKCNVVYNQSEDQPMATDRVKALNEYINRLHWCYFNYS-DLVRLAAVRTCRAVL----QSIGIKVGTILEHGTIXXXXXXXXXXXXIDDNCQVAAEAHSVWNQFIDSLPEQLLARVSCERLEIWMCSAMQPARLSYTPGSILMPDYIIXXXXXXXXXXXXDGLDEDDGNKHHILTEFYIGGRESFITDGSSAARDDLVXXXXXXXXXXXXXXXXXFI---FHEAGIRNILISIIAQI---HLKDRLAVQRFVASMILAYWDPDHLLAMRNLNDCSL--SPLQSQLLTALEEPIYYQEILSQFKQMHKACRDLILIYIEREI 2338
            RL++LF LL++    + R AAA Q+G +   +   ++ LL+K+L Y +   W  RIAA  AV  I  N   W P     +     +L         ++    ++  +LK G  L      + +       E +  + +   R +L + LG  +      + + L   +D E   + S N+                     ++      M N  K   KR       +  +DV+           EP  K +      +E+  N+++             E   EWP   FC+EL  +L++  WEIRHGA T LRE+++  G+        + ST ++    H+ + E++V+RLLC   LD+  DFVSDE+VAPVRE+CAQ LGV   H+    V +  + LL LL  D+W V HG LLG+KY LA R DL+  LLP +   I+  L+ + DDDVR  A AAL+P+        V +   ++  +   LW+ L    D T S  T +++ LL  L     V   Q   Q       ++L   + R+ W +  ++   VR AA+ T   +L    QS  + +  I++      +L  + Q  +++ N ++      VW + +   P+Q +   SC  +  W+C  MQ   +   P  +L         A   A      + E          + YIGG E+   +   A RD +V RARL A +LL  LC        + + +       +AQ+   HL  + A+QR   SM++  W            +C L  S +Q +LL  L E +YY EI   F +M   C+ LI +  +  I
Sbjct:    2 RLERLFILLDTGTTPVTRKAAAQQLGDVVKLHPHELNNLLSKVLTYLRSPNWDTRIAAGQAVEAIVKNIPEWNPSPKPKDEVCAEDLSPEDVSTDRLSFYRFDISRLLKHGASLLGSAGAEFELQDDKSGETDPKERLARQRKQLQKKLGLDMGAAIGMDTEELFNDEDLEDACASSTNRTQPGKSLGCHFSRNHLPAAELIDSEFRPGMSNRQKNKAKRMAKLVAKQRSRDVDSNEKSNDSFEGEPEEKRRKTTNVVIEQPANDSKVLIDNVPDNSSLFEETQEWPLESFCDELCNDLFNPSWEIRHGAGTGLREVLKCHGA---GGGKTVGSTAEQMERQHQEWLEDLVIRLLCVFALDRFGDFVSDEVVAPVRETCAQTLGVALRHMENSGVAMTVDILLKLLTEDQWEVRHGGLLGIKYALAVRQDLIAELLPRVLPAITEGLR-DLDDDVRAVAAAALIPVV----DGLVQLQPAKVPFIVDTLWNALLELDDLTAS--TNSIMTLLSSLLTYPQV--RQCSTQ-------QSLTVLVPRV-WPFLRHTIASVRRAALDTLFTLLSKADQSCAVWLNPIMQD-----MLRHIFQSCILESNQEILELIQKVWRELLRQAPQQYVVAASCPWMGAWLCLMMQAPHIPIDPNMLLEVKARFKEKAAGKARQGSVPVKET--------VQEYIGGAETVTEE--PATRDYVVTRARLMAAKLLGALCSCICDPRLNSSSLELRPAESLAQLLLFHLNSKSALQRIAVSMVICEWAGLQ-------KECELLSSVVQPRLLVILSEQLYYDEIAIPFTRMQNECKQLIALLADAHI 796          

Query: 3683 KLRQYQEEGVNWLGFLNRYGLHGVLADDMGLGKTLQAICVIAG-EYSRAPSTCP--------PSLIVCPPTLTVHWHQEFKKFLVNLPDFNTIVYLGTPMY----RQCIFNSLSRYQVVITSYDTLRSDMNLLARPTFPRCGTDVTKGSLMANSNVWNYVVLDEGHLIRNYKSKVAVATRALCARHRLVLTGTPIQNRVGELWSLFDFLMPGLLGTCTEFNRRYGRVLEQNGSNSGRKVDSEAGTLALELLHRQVLPFMLRRVKDDVLQ--ELPPKIMQDYMCTMSPLQLRLYTHCMESQAATDTDFVELVDKSYKENSAINQHRHGFQTMHYLRLVCNHPSLGLTSSHPLYRTLMRELAANNQCLDDINLSGKLVALRQLILDCGVGVSGAGEEELDETSVVASNRLLVFCQSIKMMELVDKMIRNEIPKATHLRLDGSVPAKDRQQIVEKFSCDAXXXXXXXXXXXXXXXXXXXXANIVIFVEHDWNPMRDLQAMDRAHRIGQKHTVIVYRLITAQSIEEKIMNLQEFKKFLANAVVSKDNNQMASMNTENILEIMNKEANWPTQSPPASANGKQKVVSSVSGGTETQLGSKSVLSKISKA----------DSGER 5461
            KL +YQ+ GV W+  L+     G+L D+MGLGKT+Q I  +AG  YS+  +           P++IVCP T+   W +EF  +    P F   V   T  +     + I   ++ + ++ITSY  +R   + + R                     W+YV+LDEGH IRN  + V  A +     HR +L+G+P+QN + ELWSLFDF+ PG LGT   F  ++   +   G  +   V  +       +L   + P++LRR+K DV     LP K  Q   C ++  Q ++Y   ++S+                    +N     F  +  LR +CNHP L  T    L R +  +     +       SGK++ +  L+                       +R+L+F QS +M+E+++  ++      ++L++DG+     RQ ++ +F+ +  I + +LTT +GGLG+NLT AN V+  + DWNP  D QA +RA RIGQK  V VYRL+TA +IEEKI + Q FK+FL N V+ KD  Q     + +I E+        T S P  + G +        G++ Q+  +   S  S+           DSG R
Sbjct:  482 KLFKYQQTGVRWMWELHCQQAGGILGDEMGLGKTIQIIAFLAGLSYSKLKTRGSNYRYAGLGPTVIVCPATVMHQWVKEFHTWW---PPFRVAVLHDTGSFTSKKEKLIPEIVASHGILITSYSYIRIMQDYIQRYD-------------------WHYVILDEGHKIRNPNAGVTTACKQFRTPHRFILSGSPMQNNLKELWSLFDFVFPGKLGTLPVFMEQFSVPITMGGYANASPVQVQTAYKCACVLRDTINPYLLRRMKADVKANLSLPDKNEQVLFCRLTEDQRQVYQTFLDSKEVYQI---------------LNGDMQVFSGLIALRKICNHPDL-FTGGPRLLRGIPHDQLTEEEHFGYWKRSGKMIVVESLL----------------RLWHKQGHRVLLFTQSRQMLEILEVFVKEN--GFSYLKMDGTTTIASRQPLIAQFNQNKDIFVFILTTRVGGLGVNLTGANRVVIYDPDWNPSTDTQARERAWRIGQKQQVTVYRLLTAGTIEEKIYHRQIFKQFLTNRVL-KDPKQRRFFKSNDIYELF-------TLSSPDGSQGTETSAIFAGTGSDVQVPKRHKTSSPSQGTTRPSLSHSTDSGNR 1035          

Query: 3671 VVSAKLRQYQEEGVNWLGFLNRYGLHGVLADDMGLGKTLQAICVIA--GEYSRAPSTCPPSLIVCPPTLTVHWHQEFKKFLVNLPDFNTIVYLGTPMYRQCIFNSL--SRYQVVITSYDTLRSDMNLLARPTFPRCGTDVTKGSLMANSNVWNYVVLDEGHLIRNYKSKVA-VATRALCARHRLVLTGTPIQNRVGELWSLFDFLMPGLLGTCTEFNRRYGRVLEQNGSNSGRKVD--SEAGTLALELLHRQVLPFMLRRVKDDVLQELPPKIMQDYMCTMSPLQLRLYTHCMESQAATDTDFVELVDKSYKENSAINQHRHGFQTMHYLRLVCNHPSLGLTSSHPLYRTLMRELAANN---QCLDDINLSGKLVALRQLILDCGVGVSGAGEEELDETSVVASN-RLLVFCQSIKMMELVDKMI--RNEIPKATHLRLDGSVPAKDRQQIVEKFSCDAXXXXX-XXXXXXXXXXXXXXXANIVIFVEHDWNPMRDLQAMDRAHRIGQKHTVIVYRLITAQSIEEKIMNLQEFK 5230
            +++ +L+QYQ +G+ WL  L    L+G+LAD+MGLGKT+Q I +I    EY R      P LI+ P +   +W  EF K+    P    + Y G+P  R+     L   ++ V++T+Y+ +  D  +LA+                     W Y+++DEGH ++N+  K+  V      A  R++LTGTP+QN++ ELW+L +FL+P +  +C+ F + +        + +G KVD   E   L +  LH+ + PF+LRR+K +V  +LP K+     C MS LQ  LY H M+++    TD  E   K       +        T+  LR +CNHP +       +  T    L  +    Q LD    SGK   L +++                   + A+N ++L+FCQ   +M +++     RN      +LRLDG+  A+DR  +++ F+  AS   + LL+T  GGLGLNL SA+ VI  + DWNP +DLQA DRAHRIGQ + V V RL T  S+EEKI+   ++K
Sbjct:  702 LINGQLKQYQIKGLEWLVSLYNNNLNGILADEMGLGKTIQTIALITYLMEYKRLNG---PYLIIVPLSTLSNWVYEFDKWA---PSVVKVSYKGSPAARRAFVPQLRSGKFNVLLTTYEYIIKDKQILAKIR-------------------WKYMIVDEGHRMKNHHCKLTQVLNTHYLAPRRVLLTGTPLQNKLPELWALLNFLLPTIFKSCSTFEQWFNAPF----AMTGEKVDLNEEETILIIRRLHKVLRPFLLRRLKKEVEAQLPEKVEYVIKCDMSALQRVLYRH-MQAKGVLLTDGSEKDKKGKGGTKTL------MNTIMQLRKICNHPYM----FQQIEETFSEHLGFSGGIVQGLDLYRASGKFEVLDRIL-----------------PKLRATNHKVLLFCQMTSLMTIMEDYFAYRN----FKYLRLDGTTKAEDRGMLLKTFNDPASQYFIFLLSTRAGGLGLNLQSADTVIIFDSDWNPHQDLQAQDRAHRIGQLNEVRVLRLCTVNSVEEKILAAAKYK 1174          

Query: 3671 VVSAKLRQYQEEGVNWLGFLNRYGLHGVLADDMGLGKTLQAICVIA--GEYSRAPSTCPPSLIVCPPTLTVHWHQEFKKFLVNLPDFNTIVYLGTPMYRQCIFNSL--SRYQVVITSYDTLRSDMNLLARPTFPRCGTDVTKGSLMANSNVWNYVVLDEGHLIRNYKSKVA-VATRALCARHRLVLTGTPIQNRVGELWSLFDFLMPGLLGTCTEFNRRYGRVLEQNGSNSGRKVD--SEAGTLALELLHRQVLPFMLRRVKDDVLQELPPKIMQDYMCTMSPLQLRLYTHCMESQAATDTDFVELVDKSYKENSAINQHRHGFQTMHYLRLVCNHPSLGLTSSHPLYRTLMRELAANNQCLDDINL---SGKLVALRQLILDCGVGVSGAGEEELDETSVVASN-RLLVFCQSIKMMELVDKMI--RNEIPKATHLRLDGSVPAKDRQQIVEKFSCDAXXX-XXXXXXXXXXXXXXXXXANIVIFVEHDWNPMRDLQAMDRAHRIGQKHTVIVYRLITAQSIEEKIMNLQEFKKFLANAVV 5254
            +++  L+QYQ +G+ W+  L    L+G+LAD+MGLGKT+Q I +I    E+ R      P LI+ P +   +W  E  K+    P    I Y GTP  R+ +   L   ++ V+IT+Y+ +  D ++LA+                     W Y+++DEGH ++N+  K+  V      A  RL+LTGTP+QN++ ELW+L +FL+P +  +C+ F + +        + +G +VD   E   L +  LH+ + PF+LRR+K +V  +LP K+     C MS +Q  LY H M+ +    TD  E   K       +        T+  L+ +CNHP +       +  +    L   N  +   +L   SGK   L +++                   + A+N R+L+FCQ   +M +++     RN +    +LRLDG+  ++DR  +++KF+ + S   I LL+T  GGLGLNL +A+ V+  + DWNP +DLQA DRAHRIGQ++ V V RL T  S+EEKI+   ++K  +   V+
Sbjct:  721 LINGTLKQYQIQGLEWMVSLYNNNLNGILADEMGLGKTIQTIGLITYLMEHKRLNG---PYLIIVPLSTLSNWVYELDKW---APSIVKIAYKGTPSMRRSLVPQLRSGKFNVLITTYEYIIKDKHILAKIR-------------------WKYMIVDEGHRMKNHHCKLTQVLNTHYVAPRRLLLTGTPLQNKLPELWALLNFLLPTIFKSCSTFEQWFNAPF----AMTGERVDLNEEETILIIRRLHKVLRPFLLRRLKKEVESQLPEKVEYVIKCDMSAIQKVLYRH-MQGKGILLTDGSEKDKKGKGGAKTL------MNTIMQLKKICNHPYM----FQHIEESFAEHLGFPNGIISGPDLYRASGKFELLDRIL-----------------PKLKATNHRVLLFCQMTSLMTILEDYFGYRNFL----YLRLDGTTKSEDRAMLLKKFNEEGSQYFIFLLSTRAGGLGLNLQAADTVVIFDSDWNPHQDLQAQDRAHRIGQQNEVRVLRLCTVNSVEEKILAAAKYKLNVDQKVI 1201          

Query: 3374 GAIELIYLVCHS---GLLPYRLAIAVIILPVVLACLNAPFDPLRRVATHVFSXXXXXXXXESSGADLSILTPARQQQRKQHLSFLDSLLNPKLIGQYNAHHSVVSAKLRQYQEEGVNWLGFLNRYGLHGVLADDMGLGKTLQAICVIAGEYSRAP--------STCPPSLIVCPPTLTVHWHQEFKKFLVNLPDFNTIVYLGTPMYRQCIFNSLSRYQVVITSYDTLRSDMNLLARPTFPRCGTDVTKGSLMANSNVWNYVVLDEGHLIRNYKSKVAVATRALCARHRLVLTGTPIQNRVGELWSLFDFLMPGLLGTCTEFNRRYGRVLEQNGSNSGRKVDSEAGTLALELLHRQVLPFMLRRVKDDVLQELPPKIMQDYMCTMSPLQLRLYTHCMESQAATDTDFVELVDKSYKENS--AINQHRHGFQTMHYLRLVCNHPSLGLTSSHPLYRTLMRELAANNQCLDDINLSGKLVALRQLILDCGVGVSGAGEEELDETSVVASNRLLVFCQSIKMMELVDK-MIRNEIPKATHLRLDGSVPAKDRQQIVEKFSCDAXXXXXXXXXXXXXXXXXXXXANIVIFVEHDWNPMRDLQAMDRAHRIGQKHTVIVYRLITAQSIEEKIMNLQEFKKFLANAVVSKDNNQMASMNTENILEIMNKEANWPTQSPPASANGKQKVVSSVSGGTETQLGSKSVLSKISKADSGERVYDCLDEYDQEYNLDSFV 5515
            GA+E +  +      G++PY   I ++++PV L  ++   D +R +AT  F+ L+ L+PLE+   D   ++    + + +  +FL+ LL+ K +  Y     +  A+LR+YQ++GVNWL FLN+Y LHG+L DDMGLGKTLQ+IC++AG++ +          +     L VCPPTLT HW  E  KF  +    N + Y G P  R  + + + ++ +V+ SYD +R+D++      F                   NY +LDEGH+I+N K+K++ A + L A +R++L+GTPIQN V ELWSLFDFLMPG LGT  +F  RYG+ +  +        + EAG LA+E LHRQVLPF+LRR+K+DVLQ+LPPKI+QDY C++SPLQ++LY    +S+A TD D         +EN    +    H FQ + YLR +CNHP+L LT+ HP Y+ +  +L   N  L DI  + KL AL+QL+LDCG+G  G  E   +  +VVA +R+L+FCQ   M+++V++ +++  +P  T+LRLDG++PA  R  IV +F+ D SID+LLLTT +GGLGLNLT A+ V+FVEHDWNPMRDLQAMDRAHRIGQK  V VYRLIT  ++EEKIM LQ+FK  +AN V+S++N  + SM T+ +L++   + +  ++   A+   K+   SS+          KS+L  + +  + E       +YD E++LD+F+
Sbjct: 1139 GAMEALACIMEQLDVGIVPY---IVLLVVPV-LGRMSDQTDSVRFMATQCFATLIRLMPLEAGIPDPPSMSEELIKLKARERNFLEQLLDGKKLENYTIPVPI-KAELRKYQQDGVNWLAFLNKYKLHGILCDDMGLGKTLQSICILAGDHCQRIFQKINLRIACLGLRLFVCPPTLTGHWVDEVGKF-CSKEYLNPLHYTGPPTERARLQHQVKKHNMVVASYDVVRNDIDFFRNIKF-------------------NYCILDEGHVIKNGKTKLSKAVKQLSANYRIILSGTPIQNNVLELWSLFDFLMPGFLGTERQFAARYGKPILASRDARSSSREQEAGVLAMEALHRQVLPFLLRRMKEDVLQDLPPKIIQDYYCSLSPLQVQLYEDFAKSRAKTDIDETVSTTSLIEENEKPKVKATGHVFQALQYLRKLCNHPALVLTTQHPEYKKISEQLGVQNSSLRDIQHAPKLSALKQLLLDCGLGNGGTAESGTE--AVVAQHRILIFCQLKSMLDIVEQDLLKPHLPSVTYLRLDGTIPAGQRHSIVSRFNNDPSIDVLLLTTHVGGLGLNLTGADTVVFVEHDWNPMRDLQAMDRAHRIGQKRVVNVYRLITRGTLEEKIMGLQKFKMSIANTVISQENASLQSMGTDQLLDLFTLDKDGKSEKADAA---KESGKSSM----------KSILDGLGELWNQE-------QYDSEFSLDNFM 1819          

Query:   89 RLDKLFELLESNHQNI-RNAAAIQIGQLSANNQVNISALLAKLLPYAKHKIWVVRIAASDAVRHIGNNAKLWVPGTS-------ESNVTNVSNL--INLENLNLHDILKIGTRLYSRDFKDLD-------EANTNQNINRDE--LARHLGFLIPDECEI--KNLITVKDCELVESKSE-NKMSVEL---AVMKSMENSPKKPVKR---------------------------PHEEVQDV-----NEPGTKMKCV--EKIGNETERERNTEWPWVDFCEELLKNLWDAKWEIRHGAATCLRELIRSQGSIMLPKNANISSTDKFAAC--------HERFQEEIVVRLLCTLTLDQLSDFVSDEMVAPVRESCAQALGVISVHLTRRLVEILANQLLSLLNHDEWRVNHXXXXXXXXXXXXRMDLVEVLLPIIYDPISSHLKGNXXXXXXXXXXXXLMPLFGDCCSNTVAISNEELDTLKTDLWDVLAVRIDCTTSGATCAVLQLLERLY-----EKCNVVYNQSEDQPMATDRVKALNEYINRLHWCYFNYS-DLVRLAAVRTCRAVLQSIGIKVGTILEHGTIXXXXXXXXXXXXIDDNCQVAAEAHSVWNQFIDSLPEQLLARVSCERLEIWMCSAMQPARL 1801
            RLD+LF LL++    + R AAA Q+G++   +   ++ LL+K+L Y +   W  RIAA  AV  I  N   W P T        E +    S+L  ++ +  ++  +LK G  L      + +       E +  + I R    L R LG  +     +  + L   +D + + + +  NK + E      +  M N  K   KR                           P E+ + V     N+P T+ K +      N +  +   EWP   F EEL  +L++  WE+RHGA T LRE++++ G           S  K A C        H+ + E++ +RLLC   LD+  DFVSDE+VAPVRE+CAQ LGV+  H+    V      LL LLN ++W V HG LLG+KY LA R DL+  LLP     I   L+ + DDDVR  A A+L+P+      + V +  +++  + + LWD L    D T S  T +++ LL  L      ++CNV               ++L   + R+ W +  ++   VR AA+ T   +L +        L    +  ++  + Q  +++ N ++    H VW + ++    Q +   +C  +  W+C  MQP+ +
Sbjct:    2 RLDRLFILLDTGTTPVTRKAAAQQLGEVVKLHPHELNNLLSKVLVYLRSPNWDTRIAAGQAVEAIVKNIPEWNPATRLKKEPGLEGSNEESSHLERLSFDRFDISRLLKHGASLLGSAGAEFEVQDDKTGEVDPKERIARQRKLLQRKLGLDMGAAIGMSTEELFNDEDLDYMPTTALLNKPAAEFIDSEFLPGMSNRQKNKAKRMAKLIAKQRSRDTIETNEKSSDSTDGEPEEKRRKVTNVVINQPATESKVLIDNVPDNSSPYDEINEWPLESFSEELCNDLFNPSWEVRHGAGTGLREILKAHGR----------SGGKIADCTLEEMKQQHQDWLEDLAIRLLCVFALDRFGDFVSDEVVAPVRETCAQTLGVVLKHMNENGVHNTVKILLKLLNQEQWEVRHGGLLGIKYALAIRQDLINSLLPKALPAIVEGLQ-DLDDDVRAVAAASLVPV----VDSLVKLQFKQVPFIMSTLWDALLELDDLTAS--TNSIMTLLSSLLMYPQVQQCNV--------------QQSLTILVPRV-WPFLRHTISSVRKAALETLCTLLSTQDQNCSGWLT-PILQDMMRHIFQICILESNQEIIDLIHKVWQELLNKASVQYVVAAACPWMGAWLCLMMQPSHI 612          

Query: 3374 GAIELIYLVCHS---GLLPYRLAIAVIILPVVLACLNAPFDPLRRVATHVFSXXXXXXXXESSGADLSILTPARQQQRKQHLSFLDSLLNPKLIGQYNAHHSVVSAKLRQYQEEGVNWLGFLNRYGLHGVLADDMGLGKTLQAICVIAGEY--SRAPSTCPPSLIVCPPTLTVHWHQEFKKFLVNLPDFNTIVYLGTPMYRQCIFNSLSRYQVVITSYDTLRSDMNLLARPTFPRCGTDVTKGSLMANSNVWNYVVLDEGHLIRNYKSKVAVATRALCARHRLVLTGTPIQNRVGELWSLFDFLMPGLLGTCTEFNRRYGRVLEQNGSNSGRKVDSEAGTLALELLHRQVLPFMLRRVKDDVLQELPPKIMQDYMCTMSPLQLRLYTHCMESQAATDTDFVELVDKSYKENS--AINQHRHGFQTMHYLRLVCNHPSLGLTSSHPLYRTLMRELAANNQCLDDINLSGKLVALRQLILDCGVGVSGAGEEELDETSVVASNRLLVFCQSIKMMELVDK-MIRNEIPKATHLRLDGSVPAKDRQQIVEKFSCDAXXXXXXXXXXXXXXXXXXXXANIVIFVEHDWNPMRDLQAMDRAHRIGQKHTVIVYRLITAQSIEEKIMNLQEFKKFLANAVVSKDNNQMASMNTENILEIMNKEANWPTQSPPASANGKQKVVSSVSGGTETQLGSKSVLSKISKADSGERVYDCLDEYDQEYNLDSFV 5515
            GA+E +  +      G++PY   I ++++PV L  ++   D +R +AT  F+ L+ L+PLE+   D   ++    + + +  +FL+ LL+ K +  Y     +  A+LR+YQ++GVNWL FLN+Y LHG+L DDMGLGKTLQ+IC++AG++     P         C P  ++   +E+          N + Y G P  R  + + + ++ +V+ SYD +R+D++      F                   NY +LDEGH+I+N K+K++ A + L A +R++L+GTPIQN V ELWSLFDFLMPG LGT  +F  RYG+ +  +        + EAG LA+E LHRQVLPF+LRR+K+DVLQ+LPPKI+QDY C++SPLQ++LY    +S+A TD D         +EN    +    H FQ + YLR +CNHP+L LT+ HP Y+ +  +L   N  L DI  + KL AL+QL+LDCG+G  G  E   +  +VVA +R+L+FCQ   M+++V++ +++  +P  T+LRLDG++PA  R  IV +F+ D SID+LLLTT +GGLGLNLT A+ V+FVEHDWNPMRDLQAMDRAHRIGQK  V VYRLIT  ++EEKIM LQ+FK  +AN V+S++N  + SM T+ +L++   + +  ++   A+   K+   SS+          KS+L  + +  + E       +YD E++LD+F+
Sbjct: 1031 GAMEALACIMEQLDVGIVPY---IVLLVVPV-LGRMSDQTDSVRFMATQCFATLIRLMPLEAGIPDPPSMSEELIKLKARERNFLEQLLDGKKLENYTIPVPI-KAELRKYQQDGVNWLAFLNKYKLHGILCDDMGLGKTLQSICILAGDHCLKNIPKNKSAD---CMPRPSLFCSKEY---------LNPLHYTGPPTERARLQHQVKKHNMVVASYDVVRNDIDFFRNIKF-------------------NYCILDEGHVIKNGKTKLSKAVKQLSANYRIILSGTPIQNNVLELWSLFDFLMPGFLGTERQFAARYGKPILASRDARSSSREQEAGVLAMEALHRQVLPFLLRRMKEDVLQDLPPKIIQDYYCSLSPLQVQLYEDFAKSRAKTDIDETVSTTSLIEENEKPKVKATGHVFQALQYLRKLCNHPALVLTTQHPEYKKISEQLGVQNSSLRDIQHAPKLSALKQLLLDCGLGNGGTAESGTE--AVVAQHRILIFCQLKSMLDIVEQDLLKPHLPSVTYLRLDGTIPAGQRHSIVSRFNNDPSIDVLLLTTHVGGLGLNLTGADTVVFVEHDWNPMRDLQAMDRAHRIGQKRVVNVYRLITRGTLEEKIMGLQKFKMSIANTVISQENASLQSMGTDQLLDLFTLDKDGKSEKADAA---KESGKSSM----------KSILDGLGELWNQE-------QYDSEFSLDNFM 1694          

Query:  650 VNEPGTKMKCV--EKIGNETERERNTEWPWVDFCEELLKNLWDAKWEIRHGAATCLRELIRSQGSIMLPKNANISSTDKFAAC--------HERFQEEIVVRLLCTLTLDQLSDFVSDEMVAPVRESCAQALGVISVHLTRRLVEILANQLLSLLNHDEWRVNHXXXXXXXXXXXXRMDLVEVLLPIIYDPISSHLKGNXXXXXXXXXXXXLMPLFGDCCSNTVAISNEELDTLKTDLWDVLAVRIDCTTSGATCAVLQLLERLY-----EKCNVVYNQSEDQPMATDRVKALNEYINRLHWCYFNYS-DLVRLAAVRTCRAVLQSIGIKVGTILEHGTIXXXXXXXXXXXXIDDNCQVAAEAHSVWNQFIDSLPEQLLARVSCERLEIWMCSAMQPARL 1801
            +N+P T+ K +      N +  +   EWP   F EEL  +L++  WE+RHGA T LRE++++ G           S  K A C        H+ + E++ +RLLC   LD+  DFVSDE+VAPVRE+CAQ LGV+  H+    V      LL LLN ++W V HG LLG+KY LA R DL+  LLP     I   L+ + DDDVR  A A+L+P+      + V +  +++  + + LWD L    D T S  T +++ LL  L      ++CNV               ++L   + R+ W +  ++   VR AA+ T   +L +        L    +  ++  + Q  +++ N ++    H VW + ++    Q +   +C  +  W+C  MQP+ +
Sbjct:  122 INQPATESKVLIDNVPDNSSPYDEINEWPLESFSEELCNDLFNPSWEVRHGAGTGLREILKAHGR----------SGGKIADCTLEEMKQQHQDWLEDLAIRLLCVFALDRFGDFVSDEVVAPVRETCAQTLGVVLKHMNENGVHNTVKILLKLLNQEQWEVRHGGLLGIKYALAIRQDLINSLLPKALPAIVEGLQ-DLDDDVRAVAAASLVPVV----DSLVKLQFKQVPFIMSTLWDALLELDDLTAS--TNSIMTLLSSLLMYPQVQQCNV--------------QQSLTILVPRV-WPFLRHTISSVRKAALETLCTLLSTQDQNCSGWLT-PILQDMMRHIFQICILESNQEIIDLIHKVWQELLNKASVQYVVAAACPWMGAWLCLMMQPSHI 488          

Query: 3374 GAIELIYLVCHS---GLLPYRLAIAVIILPVVLACLNAPFDPLRRVATHVFSXXXXXXXXESSGADLSILTPARQQQRKQHLSFLDSLLNPKLIGQYNAHHSVVSAKLRQYQEEGVNWLGFLNRYGLHGVLADDMGLGKTLQAICVIAGEY--SRAPSTCPPSLIVCPPTLTVHWHQEFKKFLVNLPDFNTIVYLGTPMYRQCIFNSLSRYQVVITSYDTLRSDMNLLARPTFPRCGTDVTKGSLMANSNVWNYVVLDEGHLIRNYKSKVAVATRALCARHRLVLTGTPIQNRVGELWSLFDFLMPGLLGTCTEFNRRYGRVLEQNGSNSGRKVDSEAGTLALELLHRQVLPFMLRRVKDDVLQELPPKIMQDYMCTMSPLQLRLYTHCMESQAATDTDFVELVDKSYKENS--AINQHRHGFQTMHYLRLVCNHPSLGLTSSHPLYRTLMRELAANNQCLDDINLSGKLVALRQLILDCGVGVSGAGEEELDETSVVASNRLLVFCQSIKMMELVDK-MIRNEIPKATHLRLDGSVPAKDRQQIVEKFSCDAXXXXXXXXXXXXXXXXXXXXANIVIFVEHDWNPMRDLQAMDRAHRIGQKHTVIVYRLITAQSIEEKIMNLQEFKKFLANAVVSKDNNQMASMNTENILEIMNKEANWPTQSPPASANGKQKVVSSVSGGTETQLGSKSVLSKISKADSGERVYDCLDEYDQEYNLDSFV 5515
            GA+E +  +      G++PY   I ++++PV L  ++   D +R +AT  F+ L+ L+PLE+   D   ++    + + +  +FL+ LL+ K +  Y     +  A+LR+YQ++GVNWL FLN+Y LHG+L DDMGLGKTLQ+IC++AG++     P         C P  ++   +E+          N + Y G P  R  + + + ++ +V+ SYD +R+D++      F                   NY +LDEGH+I+N K+K++ A + L A +R++L+GTPIQN V ELWSLFDFLMPG LGT  +F  RYG+ +  +        + EAG LA+E LHRQVLPF+LRR+K+DVLQ+LPPKI+QDY C++SPLQ++LY    +S+A TD D         +EN    +    H FQ + YLR +CNHP+L LT+ HP Y+ +  +L   N  L DI  + KL AL+QL+LDCG+G  G  E   +  +VVA +R+L+FCQ   M+++V++ +++  +P  T+LRLDG++PA  R  IV +F+ D SID+LLLTT +GGLGLNLT A+ V+FVEHDWNPMRDLQAMDRAHRIGQK  V VYRLIT  ++EEKIM LQ+FK  +AN V+S++N  + SM T+ +L++   + +  ++   A+   K+   SS+          KS+L  + +  + E       +YD E++LD+F+
Sbjct: 1128 GAMEALACIMEQLDVGIVPY---IVLLVVPV-LGRMSDQTDSVRFMATQCFATLIRLMPLEAGIPDPPSMSEELIKLKARERNFLEQLLDGKKLENYTIPVPI-KAELRKYQQDGVNWLAFLNKYKLHGILCDDMGLGKTLQSICILAGDHCLKNIPKNKSAD---CMPRPSLFCSKEY---------LNPLHYTGPPTERARLQHQVKKHNMVVASYDVVRNDIDFFRNIKF-------------------NYCILDEGHVIKNGKTKLSKAVKQLSANYRIILSGTPIQNNVLELWSLFDFLMPGFLGTERQFAARYGKPILASRDARSSSREQEAGVLAMEALHRQVLPFLLRRMKEDVLQDLPPKIIQDYYCSLSPLQVQLYEDFAKSRAKTDIDETVSTTSLIEENEKPKVKATGHVFQALQYLRKLCNHPALVLTTQHPEYKKISEQLGVQNSSLRDIQHAPKLSALKQLLLDCGLGNGGTAESGTE--AVVAQHRILIFCQLKSMLDIVEQDLLKPHLPSVTYLRLDGTIPAGQRHSIVSRFNNDPSIDVLLLTTHVGGLGLNLTGADTVVFVEHDWNPMRDLQAMDRAHRIGQKRVVNVYRLITRGTLEEKIMGLQKFKMSIANTVISQENASLQSMGTDQLLDLFTLDKDGKSEKADAA---KESGKSSM----------KSILDGLGELWNQE-------QYDSEFSLDNFM 1791          

Query:   86 SRLDKLFELLESNHQNI-RNAAAIQIGQLSANNQVNISALLAKLLPYAKHKIWVVRIAASDAVRHIGNNAKLWVPGTS-------ESNVTNVSNL--INLENLNLHDILKIGTRLYSRDFKDLD-------EANTNQNINRDE--LARHLGF------------LIPDE-------CEIKNLITVKDCELVES--------KSENK---MSVELAVMKSM------ENSPKKPVKRPHEEVQDV-----NEPGTKMKCV--EKIGNETERERNTEWPWVDFCEELLKNLWDAKWEIRHGAATCLRELIRSQGSIMLPKNANISSTDKFAAC--------HERFQEEIVVRLLCTLTLDQLSDFVSDEMVAPVRESCAQALGVISVHLTRRLVEILANQLLSLLNHDEWRVNHXXXXXXXXXXXXRMDLVEVLLPIIYDPISSHLKGNXXXXXXXXXXXXLMPLFGDCCSNTVAISNEELDTLKTDLWDVLAVRIDCTTSGATCAVLQLLERLY-----EKCNVVYNQSEDQPMATDRVKALNEYINRLHWCYFNYS-DLVRLAAVRTCRAVLQSIGIKVGTILEHGTIXXXXXXXXXXXXIDDNCQVAAEAHSVWNQFIDSLPEQLLARVSCERLEIWMCSAMQPARL 1801
            SRLD+LF LL++    + R AAA Q+G++   +   ++ LL+K+L Y +   W  RIAA  AV  I  N   W P T        E +    S+L  ++ +  ++  +LK G  L      + +       E +  + I R    L R LG             L  DE         + N       E ++S        + +NK   M+  +A  +S       E S       P E+ + V     N+P T+ K +      N +  +   EWP   F EEL  +L++  WE+RHGA T LRE++++ G           S  K A C        H+ + E++ +RLLC   LD+  DFVSDE+VAPVRE+CAQ LGV+  H+    V      LL LLN ++W V HG LLG+KY LA R DL+  LLP     I   L+ + DDDVR  A A+L+P+      + V +  +++  + + LWD L    D T S  T +++ LL  L      ++CNV               ++L   + R+ W +  ++   VR AA+ T   +L +        L    +  ++  + Q  +++ N ++    H VW + ++    Q +   +C  +  W+C  MQP+ +
Sbjct:    4 SRLDRLFILLDTGTTPVTRKAAAQQLGEVVKLHPHELNNLLSKVLVYLRSPNWDTRIAAGQAVEAIVKNIPEWNPATRLKKEPGLEGSNEESSHLERLSFDRFDISRLLKHGASLLGSAGAEFEVQDDKTGEVDPKERIARQRKLLQRKLGLDMGAAIGMSTEELFNDEDLDYMPTTALLNKPVSMPSEFIDSEFLPGMSNRQKNKAKRMAKLIAKQRSRDTIETNEKSSDSTDGEPEEKRRKVTNVVINQPATESKVLIDNVPDNSSPYDEINEWPLESFSEELCNDLFNPSWEVRHGAGTGLREILKAHGR----------SGGKIADCTLEEMKQQHQDWLEDLAIRLLCVFALDRFGDFVSDEVVAPVRETCAQTLGVVLKHMNENGVHNTVKILLKLLNQEQWEVRHGGLLGIKYALAIRQDLINSLLPKALPAIVEGLQ-DLDDDVRAVAAASLVPVV----DSLVKLQFKQVPFIMSTLWDALLELDDLTAS--TNSIMTLLSSLLMYPQVQQCNV--------------QQSLTILVPRV-WPFLRHTISSVRKAALETLCTLLSTQDQNCSGWLT-PILQDMMRHIFQICILESNQEIIDLIHKVWQELLNKASVQYVVAAACPWMGAWLCLMMQPSHI 618          

Query: 3374 GAIELIYLVCHS---GLLPYRLAIAVIILPVVLACLNAPFDPLRRVATHVFSXXXXXXXXESSGADLSILTPARQQQRKQHLSFLDSLLNPKLIGQYNAHHSVVSAKLRQYQEEGVNWLGFLNRYGLHGVLADDMGLGKTLQAICVIAGEY--SRAPSTCPPSLIVCPPTLTVHWHQEFKKFLVNLPDFNTIVYLGTPMYRQCIFNSLSRYQVVITSYDTLRSDMNLLARPTFPRCGTDVTKGSLMANSNVWNYVVLDEGHLIRNYKSKVAVATRALCARHRLVLTGTPIQNRVGELWSLFDFLMPGLLGTCTEFNRRYGRVLEQNGSNSGRKVDSEAGTLALELLHRQVLPFMLRRVKDDVLQELPPKIMQDYMCTMSPLQLRLYTHCMESQAATDTDFVELVDKSYKENS--AINQHRHGFQTMHYLRLVCNHPSLGLTSSHPLYRTLMRELAANNQCLDDINLSGKLVALRQLILDCGVGVSGAGEEELDETSVVASNRLLVFCQSIKMMELVDK-MIRNEIPKATHLRLDGSVPAKDRQQIVEKFSCDAXXXXXXXXXXXXXXXXXXXXANIVIFVEHDWNPMRDLQAMDRAHRIGQKHTVIVYRLITAQSIEEKIMNLQEFKKFLANAVVSKDNNQMASMNTENILEIMNKEANWPTQSPPASANGKQKVVSSVSGGTETQLGSKSVLSKISKADSGERVYDCLDEYDQEYNLDSFV 5515
            GA+E +  +      G++PY   I ++++PV L  ++   D +R +AT  F+ L+ L+PLE+   D   ++    + + +  +FL+ LL+ K +  Y     +  A+LR+YQ++GVNWL FLN+Y LHG+L DDMGLGKTLQ+IC++AG++     P         C P  ++   +E+          N + Y G P  R  + + + ++ +V+ SYD +R+D++      F                   NY +LDEGH+I+N K+K++ A + L A +R++L+GTPIQN V ELWSLFDFLMPG LGT  +F  RYG+ +  +        + EAG LA+E LHRQVLPF+LRR+K+DVLQ+LPPKI+QDY C++SPLQ++LY    +S+A TD D         +EN    +    H FQ + YLR +CNHP+L LT+ HP Y+ +  +L   N  L DI  + KL AL+QL+LDCG+G  G  E   +  +VVA +R+L+FCQ   M+++V++ +++  +P  T+LRLDG++PA  R  IV +F+ D SID+LLLTT +GGLGLNLT A+ V+FVEHDWNPMRDLQAMDRAHRIGQK  V VYRLIT  ++EEKIM LQ+FK  +AN V+S++N  + SM T+ +L++   + +  ++   A+   K+   SS+          KS+L  + +  + E       +YD E++LD+F+
Sbjct: 1109 GAMEALACIMEQLDVGIVPY---IVLLVVPV-LGRMSDQTDSVRFMATQCFATLIRLMPLEAGIPDPPSMSEELIKLKARERNFLEQLLDGKKLENYTIPVPI-KAELRKYQQDGVNWLAFLNKYKLHGILCDDMGLGKTLQSICILAGDHCLKNIPKNKSAD---CMPRPSLFCSKEY---------LNPLHYTGPPTERARLQHQVKKHNMVVASYDVVRNDIDFFRNIKF-------------------NYCILDEGHVIKNGKTKLSKAVKQLSANYRIILSGTPIQNNVLELWSLFDFLMPGFLGTERQFAARYGKPILASRDARSSSREQEAGVLAMEALHRQVLPFLLRRMKEDVLQDLPPKIIQDYYCSLSPLQVQLYEDFAKSRAKTDIDETVSTTSLIEENEKPKVKATGHVFQALQYLRKLCNHPALVLTTQHPEYKKISEQLGVQNSSLRDIQHAPKLSALKQLLLDCGLGNGGTAESGTE--AVVAQHRILIFCQLKSMLDIVEQDLLKPHLPSVTYLRLDGTIPAGQRHSIVSRFNNDPSIDVLLLTTHVGGLGLNLTGADTVVFVEHDWNPMRDLQAMDRAHRIGQKRVVNVYRLITRGTLEEKIMGLQKFKMSIANTVISQENASLQSMGTDQLLDLFTLDKDGKSEKADAA---KESGKSSM----------KSILDGLGELWNQE-------QYDSEFSLDNFM 1772          

Query:   86 SRLDKLFELLESNHQNI-RNAAAIQIGQLSANNQVNISALLAKLLPYAKHKIWVVRIAASDAVRHIGNNAKLWVPGT--------SESNVTNVSNLINLE-NLNLHDILKIGTRLYSRDFKDLDEANTNQNINRDELARHLGFLIPDECEIKNLITVKDCELV-ESKSENKMSVELAVMKSMENSPKKPVKRPHEEVQDVNEPGTKMKCV--EKIGNETERERNTEWPWVDFCEELLKNLWDAKWEIRHGAATCLRELIRSQGSIMLPKNANISSTDKFAAC--------HERFQEEIVVRLLCTLTLDQLSDFVSDEMVAPVRESCAQALGVISVHLTRRLVEILANQLLSLLNHDEWRVNHXXXXXXXXXXXXRMDLVEVLLPIIYDPISSHLKGNXXXXXXXXXXXXLMPLFGDCCSNTVAISNEELDTLKTDLWDVLAVRIDCTTSGATCAVLQLLERLY-----EKCNVVYNQSEDQPMATDRVKALNEYINRLHWCYFNYS-DLVRLAAVRTCRAVLQSIGIKVGTILEHGTIXXXXXXXXXXXXIDDNCQVAAEAHSVWNQFIDSLPEQLLARVSCERLEIWMCSAMQPARL 1801
            SRLD+LF LL++    + R AAA Q+G++   +   ++ LL+K+L Y +   W  RIAA  AV  I  N   W P T         +  +     L+  +  L++   + + T     D +DLD   T   +N+          +P     +     +  +L+ + +S + +        S +  P++  ++    V  +N+P T+ K +      N +  +   EWP   F EEL  +L++  WE+RHGA T LRE++++ G           S  K A C        H+ + E++ +RLLC   LD+  DFVSDE+VAPVRE+CAQ LGV+  H+    V      LL LLN ++W V HG LLG+KY LA R DL+  LLP     I   L+ + DDDVR  A A+L+P+      + V +  +++  + + LWD L    D T S  T +++ LL  L      ++CNV               ++L   + R+ W +  ++   VR AA+ T   +L +        L    +  ++  + Q  +++ N ++    H VW + ++    Q +   +C  +  W+C  MQP+ +
Sbjct:    4 SRLDRLFILLDTGTTPVTRKAAAQQLGEVVKLHPHELNNLLSKVLVYLRSPNWDTRIAAGQAVEAIVKNIPEWNPATRLKKGEVDPKERIARQRKLLQRKLGLDMGAAIGMSTEELFND-EDLDYMPTTALLNKPAAEFIDSEFLPGMSNRQKNKAKRMAKLIAKQRSRDTIETNEKSSDSTDGEPEEKRRKVTNVV--INQPATESKVLIDNVPDNSSPYDEINEWPLESFSEELCNDLFNPSWEVRHGAGTGLREILKAHGR----------SGGKIADCTLEEMKQQHQDWLEDLAIRLLCVFALDRFGDFVSDEVVAPVRETCAQTLGVVLKHMNENGVHNTVKILLKLLNQEQWEVRHGGLLGIKYALAIRQDLINSLLPKALPAIVEGLQ-DLDDDVRAVAAASLVPVV----DSLVKLQFKQVPFIMSTLWDALLELDDLTAS--TNSIMTLLSSLLMYPQVQQCNV--------------QQSLTILVPRV-WPFLRHTISSVRKAALETLCTLLSTQDQNCSGWLT-PILQDMMRHIFQICILESNQEIIDLIHKVWQELLNKASVQYVVAAACPWMGAWLCLMMQPSHI 566          

Query: 3374 GAIELIYLVCHS---GLLPYRLAIAVIILPVVLACLNAPFDPLRRVATHVFSXXXXXXXXESSGADLSILTPARQQQRKQHLSFLDSLLNPKLIGQYNAHHSVVSAKLRQYQEEGVNWLGFLNRYGLHGVLADDMGLGKTLQAICVIAGEY--SRAPSTCPPSLIVCPPTLTVHWHQEFKKFLVNLPDFNTIVYLGTPMYRQCIFNSLSRYQVVITSYDTLRSDMNLLARPTFPRCGTDVTKGSLMANSNVWNYVVLDEGHLIRNYKSKVAVATRALCARHRLVLTGTPIQNRVGELWSLFDFLMPGLLGTCTEFNRRYGRVLEQNGSNSGRKVDSEAGTLALELLHRQVLPFMLRRVKDDVLQELPPKIMQDYMCTMSPLQLRLYTHCMESQAATDTDFVELVDKSYKENS--AINQHRHGFQTMHYLRLVCNHPSLGLTSSHPLYRTLMRELAANNQCLDDINLSGKLVALRQLILDCGVGVSGAGEEELDETSVVASNRLLVFCQSIKMMELVDK-MIRNEIPKATHLRLDGSVPAKDRQQIVEKFSCDAXXXXXXXXXXXXXXXXXXXXANIVIFVEHDWNPMRDLQAMDRAHRIGQKHTVIVYRLITAQSIEEKIMNLQEFKKFLANAVVSKDNNQMASMNTENILEIMNKEANWPTQSPPASANGKQKVVSSVSGGTETQLGSKSVLSKISKADSGERVYDCLDEYDQEYNLDSFV 5515
            GA+E +  +      G++PY   I ++++PV L  ++   D +R +AT  F+ L+ L+PLE+   D   ++    + + +  +FL+ LL+ K +  Y     +  A+LR+YQ++GVNWL FLN+Y LHG+L DDMGLGKTLQ+IC++AG++     P         C P  ++   +E+          N + Y G P  R  + + + ++ +V+ SYD +R+D++      F                   NY +LDEGH+I+N K+K++ A + L A +R++L+GTPIQN V ELWSLFDFLMPG LGT  +F  RYG+ +  +        + EAG LA+E LHRQVLPF+LRR+K+DVLQ+LPPKI+QDY C++SPLQ++LY    +S+A TD D         +EN    +    H FQ + YLR +CNHP+L LT+ HP Y+ +  +L   N  L DI  + KL AL+QL+LDCG+G  G  E   +  +VVA +R+L+FCQ   M+++V++ +++  +P  T+LRLDG++PA  R  IV +F+ D SID+LLLTT +GGLGLNLT A+ V+FVEHDWNPMRDLQAMDRAHRIGQK  V VYRLIT  ++EEKIM LQ+FK  +AN V+S++N  + SM T+ +L++   + +  ++   A+   K+   SS+          KS+L  + +  + E       +YD E++LD+F+
Sbjct: 1155 GAMEALACIMEQLDVGIVPY---IVLLVVPV-LGRMSDQTDSVRFMATQCFATLIRLMPLEAGIPDPPSMSEELIKLKARERNFLEQLLDGKKLENYTIPVPI-KAELRKYQQDGVNWLAFLNKYKLHGILCDDMGLGKTLQSICILAGDHCLKNIPKNKSAD---CMPRPSLFCSKEY---------LNPLHYTGPPTERARLQHQVKKHNMVVASYDVVRNDIDFFRNIKF-------------------NYCILDEGHVIKNGKTKLSKAVKQLSANYRIILSGTPIQNNVLELWSLFDFLMPGFLGTERQFAARYGKPILASRDARSSSREQEAGVLAMEALHRQVLPFLLRRMKEDVLQDLPPKIIQDYYCSLSPLQVQLYEDFAKSRAKTDIDETVSTTSLIEENEKPKVKATGHVFQALQYLRKLCNHPALVLTTQHPEYKKISEQLGVQNSSLRDIQHAPKLSALKQLLLDCGLGNGGTAESGTE--AVVAQHRILIFCQLKSMLDIVEQDLLKPHLPSVTYLRLDGTIPAGQRHSIVSRFNNDPSIDVLLLTTHVGGLGLNLTGADTVVFVEHDWNPMRDLQAMDRAHRIGQKRVVNVYRLITRGTLEEKIMGLQKFKMSIANTVISQENASLQSMGTDQLLDLFTLDKDGKSEKADAA---KESGKSSM----------KSILDGLGELWNQE-------QYDSEFSLDNFM 1818          

Query:   86 SRLDKLFELLESNHQNI-RNAAAIQIGQLSANNQVNISALLAKLLPYAKHKIWVVRIAASDAVRHIGNNAKLWVPGTS-------ESNVTNVSNL--INLENLNLHDILKIGTRLYSRDFKDLD-------EANTNQNINRDE--LARHLGFLIPDECEI--KNLITVKDCELVESKSE-NKMSVEL---AVMKSMENSPKKPVKR---------------------------PHEEVQDV-----NEPGTKMKCV--EKIGNETERERNTEWPWVDFCEELLKNLWDAKWEIRHGAATCLRELIRSQGSIMLPKNANISSTDKFAAC--------HERFQEEIVVRLLCTLTLDQLSDFVSDEMVAPVRESCAQALGVISVHLTRRLVEILANQLLSLLNHDEWRVNHXXXXXXXXXXXXRMDLVEVLLPIIYDPISSHLKGNXXXXXXXXXXXXLMPLFGDCCSNTVAISNEELDTLKTDLWDVLAVRIDCTTSGATCAVLQLLERLY-----EKCNVVYNQSEDQPMATDRVKALNEYINRLHWCYFNYS-DLVRLAAVRTCRAVLQSIGIKVGTILEHGTIXXXXXXXXXXXXIDDNCQVAAEAHSVWNQFIDSLPEQLLARVSCERLEIWMCSAMQPARL 1801
            SRLD+LF LL++    + R AAA Q+G++   +   ++ LL+K+L Y +   W  RIAA  AV  I  N   W P T        E +    S+L  ++ +  ++  +LK G  L      + +       E +  + I R    L R LG  +     +  + L   +D + + + +  NK + E      +  M N  K   KR                           P E+ + V     N+P T+ K +      N +  +   EWP   F EEL  +L++  WE+RHGA T LRE++++ G           S  K A C        H+ + E++ +RLLC   LD+  DFVSDE+VAPVRE+CAQ LGV+  H+    V      LL LLN ++W V HG LLG+KY LA R DL+  LLP     I   L+ + DDDVR  A A+L+P+      + V +  +++  + + LWD L    D T S  T +++ LL  L      ++CNV               ++L   + R+ W +  ++   VR AA+ T   +L +        L    +  ++  + Q  +++ N ++    H VW + ++    Q +   +C  +  W+C  MQP+ +
Sbjct:    4 SRLDRLFILLDTGTTPVTRKAAAQQLGEVVKLHPHELNNLLSKVLVYLRSPNWDTRIAAGQAVEAIVKNIPEWNPATRLKKEPGLEGSNEESSHLERLSFDRFDISRLLKHGASLLGSAGAEFEVQDDKTGEVDPKERIARQRKLLQRKLGLDMGAAIGMSTEELFNDEDLDYMPTTALLNKPAAEFIDSEFLPGMSNRQKNKAKRMAKLIAKQRSRDTIETNEKSSDSTDGEPEEKRRKVTNVVINQPATESKVLIDNVPDNSSPYDEINEWPLESFSEELCNDLFNPSWEVRHGAGTGLREILKAHGR----------SGGKIADCTLEEMKQQHQDWLEDLAIRLLCVFALDRFGDFVSDEVVAPVRETCAQTLGVVLKHMNENGVHNTVKILLKLLNQEQWEVRHGGLLGIKYALAIRQDLINSLLPKALPAIVEGLQ-DLDDDVRAVAAASLVPV----VDSLVKLQFKQVPFIMSTLWDALLELDDLTAS--TNSIMTLLSSLLMYPQVQQCNV--------------QQSLTILVPRV-WPFLRHTISSVRKAALETLCTLLSTQDQNCSGWLT-PILQDMMRHIFQICILESNQEIIDLIHKVWQELLNKASVQYVVAAACPWMGAWLCLMMQPSHI 615          

Query: 3374 GAIELIYLVCHS---GLLPYRLAIAVIILPVVLACLNAPFDPLRRVATHVFSXXXXXXXXESSGADLSILTPARQQQRKQHLSFLDSLLNPKLIGQYNAHHSVVSAKLRQYQEEGVNWLGFLNRYGLHGVLADDMGLGKTLQAICVIAG-------EYSRAP-STCPP--SLIVCPPTLTVHWHQEFKKFLVNLPDFNTIVYLGTPMYRQCIFNSLSRYQVVITSYDTLRSDMNLLARPTFPRCGTDVTKGSLMANSNVWNYVVLDEGHLIRNYKSKVAVATRALCARHRLVLTGTPIQNRVGELWSLFDFLMPGLLGTCTEFNRRYGRVLEQNGSNSGRKVDSEAGTLALELLHRQVLPFMLRRVKDDVLQELPPKIMQDYMCTMSPLQLRLYTHCMESQAATDTDFVELVDKSY----KENSAINQHRHGFQTMHYLRLVCNHPSLGLTSSHPLYRTLMRELAANNQCLDDINLSGKLVALRQLILDCGVGVSGAGEEELDETSVVASNRLLVFCQSIKMMELVD-KMIRNEIPKATHLRLDGSVPAKDRQQIVEKFSCDAXXXXXXXXXXXXXXXXXXXXANIVIFVEHDWNPMRDLQAMDRAHRIGQKHTVIVYRLITAQSIEEKIMNLQEFKKFLANAVVSKDNNQMASMNTENILEIMNKEANWPTQSPPASANGKQKVVSSVSGGTETQLGSKSVLSKISKADSGERVYDCLDEYDQEYNLDSFV 5515
            GAIE +  V      G++PY   I ++++PV L  ++   D +R +AT  F+ L+ L+PLE+   D   ++    Q + +   FL+ LL+ K +  Y     + +A+LR+YQ++GVNWL FLN+Y LHG+L DDMGLGKTLQ+IC++AG       EY+R+  + C P  SL+VCPPTLT HW  E  KF  +    N + Y G P  R  + + + R+ +++ SYD +R+D++      F                   NY +LDEGH+I+N K+K++ A + L A +R++L+GTPIQN V ELWSLFDFLMPG LGT  +F  RYG+ +  +        + EAG LA++ LHRQVLPF+LRR+K+DVLQ+LPPKI+QDY CT+SPLQ++LY    +S+A  D D  E V  +      E   +    H FQ + YLR +CNHP+L LT  HP +++   +L   N  L DI  + KL AL+QL+LDCG+G +G+  E   E SVVA +R+L+FCQ   M+++V+  +++  +P  T+LRLDGS+P   R  IV +F+ D SID+LLLTT +GGLGLNLT A+ V+FVEHDWNPMRDLQAMDRAHRIGQK  V VYRLIT  ++EEKIM LQ+FK  +AN V+S++N+ + SM T+ +L++   + +   +   +S +GK  +              KSVL  +S       ++D  ++YD EYNL++F+
Sbjct: 1163 GAIEALACVMEQLDVGIVPY---IVLLVVPV-LGRMSDQTDSVRFMATQCFATLIRLMPLEAGIPDPPNMSEELIQLKAKERHFLEQLLDGKKLENYKIPVPI-NAELRKYQQDGVNWLAFLNKYKLHGILCDDMGLGKTLQSICILAGDHCQRAQEYARSKLAECMPLPSLVVCPPTLTGHWVDEVGKF-CSREYLNPLHYTGPPTERIRLQHQVKRHNLIVASYDVVRNDIDFFRNIKF-------------------NYCILDEGHVIKNGKTKLSKAVKQLTANYRIILSGTPIQNNVLELWSLFDFLMPGFLGTERQFAARYGKPILASRDARSSSREQEAGVLAMDALHRQVLPFLLRRMKEDVLQDLPPKIIQDYYCTLSPLQVQLYEDFAKSRAKCDVD--ETVSSAALSEETEKPKLKATGHVFQALQYLRKLCNHPALVLTPQHPEFKSTTEKLTVQNSSLHDIQHAPKLSALKQLLLDCGLG-NGSSTESGTE-SVVAQHRILIFCQLKSMLDIVEHDLLKPHLPSVTYLRLDGSIPPGQRHSIVSRFNNDPSIDVLLLTTHVGGLGLNLTGADTVVFVEHDWNPMRDLQAMDRAHRIGQKRVVNVYRLITRGTLEEKIMGLQKFKMNIANTVISQENSSLQSMGTDQLLDLFTLDKDGKAEKADSSTSGKASM--------------KSVLENLSD------LWDA-EQYDSEYNLETFM 1844          

Query:   86 SRLDKLFELLESNHQNI-RNAAAIQIGQLSANNQVNISALLAKLLPYAKHKIWVVRIAASDAVRHIGNNAKLW--VPGT----SESNV--TNVSNLINLENLNLHDILKIGTRLYSRDFKDLD-------EANTNQNINRDE--LARHLGF------------LIPDE---------CEIKNLITVKDCELVES--------KSENK---MSVELAVMKSM------ENSPKKPVKRPHEEVQDV-----NEPGTKMKCVEKIGNETER----ERNTEWPWVDFCEELLKNLWDAKWEIRHGAATCLRELIRSQGSIMLPKNANISSTDKFAACHERFQEEIVVRLLCTLTLDQLSDFVSDEMVAPVRESCAQALGVISVHLTRRLVEILANQLLSLLNHDEWRVNHXXXXXXXXXXXXRMDLVEVLLPIIYDPISSHLKGNXXXXXXXXXXXXLMPLFGDCCSNTVAISNEELDTLKTDLWDVLAVRIDCTTSGATCAVLQLLERLYEKCNVVYNQSEDQPMATDRVKALNEYINRLHWCYFNYSDLVRLAAVRTCRAVLQSIGIKVGTILEHGTIXXXXXXXXXXXXIDDNCQVAAEA------HSVWNQFIDSLPEQLLARVSCERLEIWMCSAMQPARLSYTPGSILMPDYIIXXXXXXXXXXXXDGLDEDDGNKHHILTEFYIGGRESFITDGSSAARDDLVXXXXXXXXXXXXXXXXXFIFHEAGIRNILIS---IIAQI---HLKDRLAVQRFVASMILAYWDPDHLLAMRNLNDCSLSPLQSQLLTALEEPIYYQEILSQFKQMHKACRDLI 2314
            SRLD+LF LL++    + R AAA Q+G++   +   ++ LL+K+L Y +   W  RIAA  AV  I  N   W  VP T    +ES++  ++ ++ +N +  ++  +L+ G  L      + +       E +  + I R    L + LG             L  DE           +    T++  EL++S        + +NK   M+   A  +S       E S       P E+ + V     N+  +  K +  I N  E     E   EWP   FCEEL  +L++  WE+RHGA T LRE++++ G          S+ ++    H+ + E++V+RLLC   LD+  DFVSDE+VAPVRE+CAQ LGV+  H+    V    + LL LL  ++W V HG LLG+KY LA R D++  LLP +   I   L+ + DDDVR  A A+L+P+      + V +  +++ ++   LWD L    D T S  T +++ LL  +     + Y Q +   +     ++L   + R+ W + +++    +++VR  RA L+++   + T  E+ +   +         I   C + +        H VW + +     Q L   +C  +  W+C  MQP+ L          D  +     A A     G       ++  + + YI G ++ + D   A RD +V+RAR+ A +LL  LC         + N  I     + Q+   +L  + A+QR   ++++  W      A++         +Q +LL  L E +YY EI   F +M   C+  I
Sbjct:    4 SRLDRLFILLDTGTTPVTRKAAAQQLGEVVKLHPHELNNLLSKVLIYLRSTNWDTRIAAGQAVEAIVKNVPEWNPVPRTKQEPTESSMEDSSTTDRLNFDRFDICRLLQHGASLLGSAGAEFEVQDEKSGEVDPKERIARQRKLLQKKLGLNMGEAIGMSTEELFNDEDLDYTPTSAALVNKQSTLQAAELIDSEFRAGMSNRQKNKAKRMAKLFAKQRSRDAVETNEKSNDSTDGEPEEKRRKVANVVINQTASDSKVL--IDNVPESSSLIEETNEWPLESFCEELCNDLFNPSWEVRHGAGTGLREILKAHGKS--GGKMGDSTLEEMIQQHQEWLEDLVIRLLCVFALDRFGDFVSDEVVAPVRETCAQTLGVVLKHMNETGVHKTVDVLLKLLTQEQWEVRHGGLLGIKYALAVRQDVINTLLPKVLTRIIEGLQ-DLDDDVRAVAAASLVPV----VESLVYLQTQKVPSIINTLWDSLLELDDLTAS--TNSIMTLLSSM-----LTYPQVQQCSIQ----QSLTVLVPRV-WPFLHHT----ISSVR--RAALETLFTLLSTQDENSSSWLIPILSDMLRHIFQFCVLESSQEILDLIHKVWMELLSKASVQYLVAAACPWMSAWLCLMMQPSHLPI--------DLNMLLEVKARAKEKTGGKVRQGQIQNKEVLQEYIAGADTIMED--PATRDFVVMRARMMAAKLLGALCCYICDPSVNMVNQEIKPADSLGQLLLFYLNSKSALQRISVALVICEW-----AALQKECKAVTLAVQPRLLDILSEHLYYDEIAVPFTRMQNECKQFI 781          

Query: 3683 KLRQYQEEGVNWLGFLNRYGLHGVLADDMGLGKTLQAICVIAG-EYSRAPSTCP--------PSLIVCPPTLTVHWHQEFKKFLVNLPDFNTIVYLGTPMY----RQCIFNSLSRYQVVITSYDTLRSDMNLLARPTFPRCGTDVTKGSLMANSNVWNYVVLDEGHLIRNYKSKVAVATRALCARHRLVLTGTPIQNRVGELWSLFDFLMPGLLGTCTEFNRRYGRVLEQNGSNSGRKVDSEAGTLALELLHRQVLPFMLRRVKDDVLQ--ELPPKIMQDYMCTMSPLQLRLYTHCMESQAATDTDFVELVDKSYKENSAINQHRHGFQTMHYLRLVCNHPSLGLTSSHPLYRTLMRELAANNQCLDDINLSGKLVALRQLILDCGVGVSGAGEEELDETSVVASNRLLVFCQSIKMMELVDKMIRNEIPKATHLRLDGSVPAKDRQQIVEKFSCDAXXXXXXXXXXXXXXXXXXXXANIVIFVEHDWNPMRDLQAMDRAHRIGQKHTVIVYRLITAQSIEEKIMNLQEFKKFLANAVVSKDNNQMASMNTENILEIMNKEANWPTQSPPASANGKQKVVSSVSGGTETQL 5410
            KL +YQ+ GV WL  L+     G+L D+MGLGKT+Q I  +AG  YS+  +           P++IVCP T+   W +EF  +    P F   V   T  Y     + I + +  + V+ITSY  +R   + ++R                   + W+YV+LDEGH IRN  + V +A +     HR++L+G+P+QN + ELWSLFDF+ PG LGT   F  ++   +   G ++   V  +       +L   + P++LRR+K DV     LP K  Q   C ++  Q ++Y + ++S+A             Y+    +N     F  +  LR +CNHP   L S  P   +   E     +       SGK++ +  L+                +       R+L+F QS +M+ +++  +R    K ++L++DG+     RQ ++ K++ D SI + LLTT +GGLG+NLT AN VI  + DWNP  D QA +RA RIGQK  V VYRL+TA +IEEKI + Q FK+FL N V+ KD  Q     + ++ E+        T + P ++ G +   S++  GT + +
Sbjct:  502 KLFKYQQTGVRWLWELHCQQAGGILGDEMGLGKTIQIIAFLAGLSYSKIRTRGSNYRFEGLGPTIIVCPTTVMHQWVKEFHTWW---PPFRVAVLHETGSYTHKKERLIRDIVYCHGVLITSYSYIRLMQDDISR-------------------HDWHYVILDEGHKIRNPNAAVTLACKQFRTPHRIILSGSPMQNNLRELWSLFDFIFPGKLGTLPVFMEQFSVPITMGGYSNASPVQVKTAYKCACVLRDTINPYLLRRMKSDVKMSLSLPDKNEQVLFCRLTDEQHKVYQNFIDSKAV------------YR---ILNGENQIFSGLVALRKICNHPD--LFSGGPKNASGPPEDELEEEQFGHWRRSGKMIVVESLL----------------KIWHRQGQRVLLFSQSRQMLHILEVFLRAH--KYSYLKMDGTTTIASRQPLITKYNEDTSIFVFLLTTRVGGLGVNLTGANRVIIYDPDWNPSTDTQARERAWRIGQKKQVTVYRLLTAGTIEEKIYHRQIFKQFLTNRVL-KDPKQRRFFKSNDLYELF-------TLTSPDASQGTE--TSAIFAGTGSSI 1025          

Query: 3671 VVSAKLRQYQEEGVNWLGFLNRYGLHGVLADDMGLGKTLQAICVIA--GEYSRAPSTCPPSLIVCPPTLTVHWHQEFKKFLVNLPDFNTIVYLGTPMYRQCIFNSL--SRYQVVITSYDTLRSDMNLLARPTFPRCGTDVTKGSLMANSNVWNYVVLDEGHLIRNYKSKVA-VATRALCARHRLVLTGTPIQNRVGELWSLFDFLMPGLLGTCTEFNRRYGRVLEQNGSNSGRKVD--SEAGTLALELLHRQVLPFMLRRVKDDVLQELPPKIMQDYMCTMSPLQLRLYTHCMESQAATDTDFVELVDKSYKENSAINQHRHGFQTMHYLRLVCNHPSLGLTSSHPLYRTLMRELAANNQCLDDINL---SGKLVALRQLILDCGVGVSGAGEEELDETSVVASN-RLLVFCQSIKMMELVDK--MIRNEIPKATHLRLDGSVPAKDRQQIVEKFS-CDAXXXXXXXXXXXXXXXXXXXXANIVIFVEHDWNPMRDLQAMDRAHRIGQKHTVIVYRLITAQSIEEKIMNLQEFKKFLANAVV 5254
            +++  L+ YQ +G+ W+  L    L+G+LAD+MGLGKT+Q I +I    E+ R      P LI+ P +   +W  EF K+    P    I Y GTP  R+ +   L   ++ V++T+Y+ +  D ++LA+                     W Y+++DEGH ++N+  K+  V      A  R++LTGTP+QN++ ELW+L +FL+P +  +C+ F + +        + +G +VD   E   L +  LH+ + PF+LRR+K +V  +LP K+     C MS LQ  LY H M+++    TD  E   K       +        T+  LR +CNHP +     H +  +    L  +N  ++   L   SGK   L +++                   + A+N R+L+FCQ   +M +++     RN +    +LRLDG+  ++DR  +++KF+   +   I LL+T  GGLGLNL +A+ V+  + DWNP +DLQA DRAHRIGQ++ V V RL T  S+EEKI+   ++K  +   V+
Sbjct:  730 LINGTLKHYQLQGLEWMVSLYNNNLNGILADEMGLGKTIQTIALITYLMEHKRLNG---PYLIIVPLSTLSNWTYEFDKWA---PSVVKISYKGTPAMRRSLVPQLRSGKFNVLLTTYEYIIKDKHILAKIR-------------------WKYMIVDEGHRMKNHHCKLTQVLNTHYVAPRRILLTGTPLQNKLPELWALLNFLLPTIFKSCSTFEQWFNAPF----AMTGERVDLNEEETILIIRRLHKVLRPFLLRRLKKEVESQLPEKVEYVIKCDMSALQKILYRH-MQAKGILLTDGSEKDKKGKGGAKTL------MNTIMQLRKICNHPYM---FQH-IEESFAEHLGYSNGVINGAELYRASGKFELLDRIL-----------------PKLRATNHRVLLFCQMTSLMTIMEDYFAFRNFL----YLRLDGTTKSEDRAALLKKFNEPGSQYFIFLLSTRAGGLGLNLQAADTVVIFDSDWNPHQDLQAQDRAHRIGQQNEVRVLRLCTVNSVEEKILAAAKYKLNVDQKVI 1210          

Query: 3671 VVSAKLRQYQEEGVNWLGFLNRYGLHGVLADDMGLGKTLQAICVIA--GEYSRAPSTCPPSLIVCPPTLTVHWHQEFKKFLVNLPDFNTIVYLGTPMYRQCIFNSL--SRYQVVITSYDTLRSDMNLLARPTFPRCGTDVTKGSLMANSNVWNYVVLDEGHLIRNYKSKVA-VATRALCARHRLVLTGTPIQNRVGELWSLFDFLMPGLLGTCTEFNRRYGRVLEQNGSNSGRKVD--SEAGTLALELLHRQVLPFMLRRVKDDVLQELPPKIMQDYMCTMSPLQLRLYTHCMESQAATDTDFVELVDKSYKENSAINQHRHGFQTMHYLRLVCNHPSLGLTSSHPLYRTLMRELAANNQCLDDINL---SGKLVALRQLILDCGVGVSGAGEEELDETSVVASN-RLLVFCQSIKMMELVDK--MIRNEIPKATHLRLDGSVPAKDRQQIVEKFS-CDAXXXXXXXXXXXXXXXXXXXXANIVIFVEHDWNPMRDLQAMDRAHRIGQKHTVIVYRLITAQSIEEKIMNLQEFK 5230
            +++  L+ YQ +G+ W+  L    L+G+LAD+MGLGKT+Q I +I    E+ R      P LI+ P +   +W  EF K+    P    I Y GTP  R+ +   L   ++ V++T+Y+ +  D ++LA+                     W Y+++DEGH ++N+  K+  V      A  R++LTGTP+QN++ ELW+L +FL+P +  +C+ F + +        + +G +VD   E   L +  LH+ + PF+LRR+K +V  +LP K+     C MS LQ  LY H M+++    TD  E   K       +        T+  LR +CNHP +     H +  +    L  +N  ++   L   SGK   L +++                   + A+N R+L+FCQ   +M +++     RN +    +LRLDG+  ++DR  +++KF+   +   I LL+T  GGLGLNL +A+ V+  + DWNP +DLQA DRAHRIGQ++ V V RL T  S+EEKI+   ++K
Sbjct:  730 LINGTLKHYQLQGLEWMVSLYNNNLNGILADEMGLGKTIQTIALITYLMEHKRLNG---PYLIIVPLSTLSNWTYEFDKWA---PSVVKISYKGTPAMRRSLVPQLRSGKFNVLLTTYEYIIKDKHILAKIR-------------------WKYMIVDEGHRMKNHHCKLTQVLNTHYVAPRRILLTGTPLQNKLPELWALLNFLLPTIFKSCSTFEQWFNAPF----AMTGERVDLNEEETILIIRRLHKVLRPFLLRRLKKEVESQLPEKVEYVIKCDMSALQKILYRH-MQAKGILLTDGSEKDKKGKGGAKTL------MNTIMQLRKICNHPYM---FQH-IEESFAEHLGYSNGVINGAELYRASGKFELLDRIL-----------------PKLRATNHRVLLFCQMTSLMTIMEDYFAFRNFL----YLRLDGTTKSEDRAALLKKFNEPGSQYFIFLLSTRAGGLGLNLQAADTVVIFDSDWNPHQDLQAQDRAHRIGQQNEVRVLRLCTVNSVEEKILAAAKYK 1202          

Query: 3671 VVSAKLRQYQEEGVNWLGFLNRYGLHGVLADDMGLGKTLQAICVIA--GEYSRAPSTCPPSLIVCPPTLTVHWHQEFKKFLVNLPDFNTIVYLGTPMYRQCIFNSL--SRYQVVITSYDTLRSDMNLLARPTFPRCGTDVTKGSLMANSNVWNYVVLDEGHLIRNYKSKVA-VATRALCARHRLVLTGTPIQNRVGELWSLFDFLMPGLLGTCTEFNRRYGRVLEQNGSNSGRKVD--SEAGTLALELLHRQVLPFMLRRVKDDVLQELPPKIMQDYMCTMSPLQLRLYTHCMESQAATDTDFVELVDKSYKENSAINQHRHGFQTMHYLRLVCNHPSLGLTSSHPLYRTLMRELAANNQCLDDINL---SGKLVALRQLILDCGVGVSGAGEEELDETSVVASN-RLLVFCQSIKMMELVDK--MIRNEIPKATHLRLDGSVPAKDRQQIVEKFS-CDAXXXXXXXXXXXXXXXXXXXXANIVIFVEHDWNPMRDLQAMDRAHRIGQKHTVIVYRLITAQSIEEKIMNLQEFK 5230
            +++  L+ YQ +G+ W+  L    L+G+LAD+MGLGKT+Q I +I    E+ R      P LI+ P +   +W  EF K+    P    I Y GTP  R+ +   L   ++ V++T+Y+ +  D ++LA+                     W Y+++DEGH ++N+  K+  V      A  R++LTGTP+QN++ ELW+L +FL+P +  +C+ F + +        + +G +VD   E   L +  LH+ + PF+LRR+K +V  +LP K+     C MS LQ  LY H M+++    TD  E   K       +        T+  LR +CNHP +     H +  +    L  +N  ++   L   SGK   L +++                   + A+N R+L+FCQ   +M +++     RN +    +LRLDG+  ++DR  +++KF+   +   I LL+T  GGLGLNL +A+ V+  + DWNP +DLQA DRAHRIGQ++ V V RL T  S+EEKI+   ++K
Sbjct:  730 LINGTLKHYQLQGLEWMVSLYNNNLNGILADEMGLGKTIQTIALITYLMEHKRLNG---PYLIIVPLSTLSNWTYEFDKWA---PSVVKISYKGTPAMRRSLVPQLRSGKFNVLLTTYEYIIKDKHILAKIR-------------------WKYMIVDEGHRMKNHHCKLTQVLNTHYVAPRRILLTGTPLQNKLPELWALLNFLLPTIFKSCSTFEQWFNAPF----AMTGERVDLNEEETILIIRRLHKVLRPFLLRRLKKEVESQLPEKVEYVIKCDMSALQKILYRH-MQAKGILLTDGSEKDKKGKGGAKTL------MNTIMQLRKICNHPYM---FQH-IEESFAEHLGYSNGVINGAELYRASGKFELLDRIL-----------------PKLRATNHRVLLFCQMTSLMTIMEDYFAFRNFL----YLRLDGTTKSEDRAALLKKFNEPGSQYFIFLLSTRAGGLGLNLQAADTVVIFDSDWNPHQDLQAQDRAHRIGQQNEVRVLRLCTVNSVEEKILAAAKYK 1202          

Query: 3374 GAIELIYLVCHS---GLLPYRLAIAVIILPVVLACLNAPFDPLRRVATHVFSXXXXXXXXESSGADLSILTPARQQQRKQHLSFLDSLLNPKLIGQYNAHHSVVSAKLRQYQEEGVNWLGFLNRYGLHGVLADDMGLGKTLQAICVIAG-------EYSRAP-STCPP--SLIVCPPTLTVHWHQEFKKFLVNLPDFNTIVYLGTPMYRQCIFNSLSRYQVVITSYDTLRSDMNLLARPTFPRCGTDVTKGSLMANSNVWNYVVLDEGHLIRNYKSKVAVATRALCARHRLVLTGTPIQNRVGELWSLFDFLMPGLLGTCTEFNRRYGRVLEQNGSNSGRKVDSEAGTLALELLHRQVLPFMLRRVKDDVLQELPPKIMQDYMCTMSPLQLRLYTHCMESQAATDTDFVELVDKSY----KENSAINQHRHGFQTMHYLRLVCNHPSLGLTSSHPLYRTLMRELAANNQCLDDINLSGKLVALRQLILDCGVGVSGAGEEELDETSVVASNRLLVFCQSIKMMELVD-KMIRNEIPKATHLRLDGSVPAKDRQQIVEKFSCDAXXXXXXXXXXXXXXXXXXXXANIVIFVEHDWNPMRDLQAMDRAHRIGQKHTVIVYRLITAQSIEEKIMNLQEFKKFLANAVVSKDNNQMASMNTENILEIMNKEANWPTQSPPASANGKQKVVSSVSGGTETQLGSKSVLSKISKADSGERVYDCLDEYDQEYNLDSFV 5515
            GAIE +  V      G++PY   I ++++PV L  ++   D +R +AT  F+ L+ L+PLE+   D   ++    Q + +   FL+ LL+ K +  Y     + +A+LR+YQ++GVNWL FLN+Y LHG+L DDMGLGKTLQ+IC++AG       EY+R+  + C P  SL+VCPPTLT HW  E  KF  +    N + Y G P  R  + + + R+ +++ SYD +R+D++      F                   NY +LDEGH+I+N K+K++ A + L A +R++L+GTPIQN V ELWSLFDFLMPG LGT  +F  RYG+ +  +        + EAG LA++ LHRQVLPF+LRR+K+DVLQ+LPPKI+QDY CT+SPLQ++LY    +S+A  D D  E V  +      E   +    H FQ + YLR +CNHP+L LT  HP ++T   +LA  N  L DI  + KL AL+QL+LDCG+G +G+  E   E SVVA +R+L+FCQ   M+++V+  +++  +P  T+LRLDGS+P   R  IV +F+ D SID+LLLTT +GGLGLNLT A+ V+FVEHDWNPMRDLQAMDRAHRIGQK  V VYRLIT  ++EEKIM LQ+FK  +AN V+S++N+ + SM T+ +L++   + +   +    S +GK  +              KS+L  +S       ++D  ++YD EY+L++F+
Sbjct: 1164 GAIEALACVMEQLDVGIVPY---IVLLVVPV-LGRMSDQTDSVRFMATQCFATLIRLMPLEAGIPDPPNMSAELIQLKAKERHFLEQLLDGKKLENYKIPVPI-NAELRKYQQDGVNWLAFLNKYKLHGILCDDMGLGKTLQSICILAGDHCHRAQEYARSKLAECMPLPSLVVCPPTLTGHWVDEVGKF-CSREYLNPLHYTGPPTERIRLQHQVKRHNLIVASYDVVRNDIDFFRNIKF-------------------NYCILDEGHVIKNGKTKLSKAVKQLTANYRIILSGTPIQNNVLELWSLFDFLMPGFLGTERQFAARYGKPILASRDARSSSREQEAGVLAMDALHRQVLPFLLRRMKEDVLQDLPPKIIQDYYCTLSPLQVQLYEDFAKSRAKCDVD--ETVSSATLSEETEKPKLKATGHVFQALQYLRKLCNHPALVLTPQHPEFKTTAEKLAVQNSSLHDIQHAPKLSALKQLLLDCGLG-NGSTSESGTE-SVVAQHRILIFCQLKSMLDIVEHDLLKPHLPSVTYLRLDGSIPPGQRHSIVSRFNNDPSIDVLLLTTHVGGLGLNLTGADTVVFVEHDWNPMRDLQAMDRAHRIGQKRVVNVYRLITRGTLEEKIMGLQKFKMNIANTVISQENSSLQSMGTDQLLDLFTLDKDGKAEKADTSTSGKASM--------------KSILENLSD------LWD-QEQYDSEYSLENFM 1845          

Query:  137 RNAAAIQIGQLSANNQVNISALLAKLLPYAKHKIWVVRIAASDAVRHIGNNAKLWVP-------GTSESNVTN--VSNLINLENLNLHDILKIGTRLYSRDFKDLD-------EANTNQNINRDE--LARHLGF------------LIPDE---------CEIKNLITVKDCELVES--------KSENK---MSVELAVMKSM------ENSPKKPVKRPHEEVQDV-----NEPGTKMKC-VEKIGNETER-ERNTEWPWVDFCEELLKNLWDAKWEIRHGAATCLRELIRSQGSIMLPKNANISSTDKFAACHERFQEEIVVRLLCTLTLDQLSDFVSDEMVAPVRESCAQALGVISVHLTRRLVEILANQLLSLLNHDEWRVNHXXXXXXXXXXXXRMDLVEVLLPIIYDPISSHLKGNXXXXXXXXXXXXLMPLFGDCCSNTVAISNEELDTLKTDLWDVLAVRIDCTTSGATCAVLQLLERLYEKCNVVYNQSEDQPMATDRVKALNEYINRLHWCYFNYSDLVRLAAVRTCRAVLQSIGIKVGTILEHGTIXXXXXXXXXXXXIDDNCQVAAEA------HSVWNQFIDSLPEQLLARVSCERLEIWMCSAMQPARLSYTPGSILMPDYIIXXXXXXXXXXXXDGLDEDDGNKHHILTEFYIGGRESFITDGSSAARDDLVXXXXXXXXXXXXXXXXXFIFHEAGIRNILISI-----IAQI---HLKDRLAVQRFVASMILAYWDPDHLLAMRNLNDCSLSPLQSQLLTALEEPIYYQEILSQFKQMHKACRDLI 2314
            R AAA Q+G++   +   ++ LL+K+L Y +   W  RIAA  AV  I  N   W P        TSES++ +   +  +N +  ++  +L+ G  L      + +       E +  + I R    L + LG             L  DE           +    T++  EL++S        + +NK   M+   A  +S       E S       P E+ + +     N+     K  ++ I + +   E   EWP   FCEEL  +L++  WE+RHGA T LRE++++ G          S+ ++    H+ + E++V+RLLC   LD+  DFVSDE+VAPVRE+CAQ LGV+  H+    V    + LL LL  ++W V HG LLG+KY LA R D++  LLP +   I   L+ + DDDVR  A A+L+P+      + V +  +++  +   LWD L    D T S  T +++ LL  L     + Y Q +   +     ++L   + R+ W + +++    +++VR  RA L+++   + T  ++ +   +         I   C + +        H VW + +     Q +   +C  +  W+C  MQP+ L          D  +     A A     G      +++  + + YI G ++ + D   A RD +V+RAR+ A +LL  LC      + G+  +   I     + Q+   HL  + A+QR   ++++  W      A++         +Q +LL  L E +YY EI   F +M   C+ LI
Sbjct:   22 RKAAAQQLGEVVKLHPHELNNLLSKVLIYLRSANWDTRIAAGQAVEAIVKNVPEWNPVPRTRQEPTSESSMEDSPTTERLNFDRFDICRLLQHGASLLGSAGAEFEVQDEKSGEVDPKERIARQRKLLQKKLGLNMGEAIGMSTEELFNDEDLDYTPTSASFVNKQPTLQAAELIDSEFRAGMSNRQKNKAKRMAKLFAKQRSRDAVETNEKSNDSTDGEPEEKRRKIANVVINQSANDSKVLIDNIPDSSSLIEETNEWPLESFCEELCNDLFNPSWEVRHGAGTGLREILKAHGKS--GGKMGDSTLEEMIQQHQEWLEDLVIRLLCVFALDRFGDFVSDEVVAPVRETCAQTLGVVLKHMNETGVHKTVDVLLKLLTQEQWEVRHGGLLGIKYALAVRQDVINTLLPKVLTRIIEGLQ-DLDDDVRAVAAASLVPVV----ESLVYLQTQKVPFIINTLWDALLELDDLTAS--TNSIMTLLSSL-----LTYPQVQQCSIQ----QSLTVLVPRV-WPFLHHT----ISSVR--RAALETLFTLLSTQDQNSSSWLIPILPDMLRHIFQFCVLESSQEILDLIHKVWMELLSKASVQYVVAAACPWMGAWLCLMMQPSHLPI--------DLNMLLEVKARAKEKTGGKVRQGQSQNKEVLQEYIAGADTIMED--PATRDFVVMRARMMAAKLLGALCCCIC--DPGVNVVTQEIKPAESLGQLLLFHLNSKSALQRISVALVICEW-----AALQKECKAVTLAVQPRLLDILSEHLYYDEIAVPFTRMQNECKQLI 782          

Query: 3374 GAIELIYLVCH---SGLLPYRLAIAVIILPVVLACLNAPFDPLRRVATHVFSXXXXXXXXESSGADLSILTPARQQQRKQHLSFLDSLLNPKLIGQYNAHHSVVSAKLRQYQEEGVNWLGFLNRYGLHGVLADDMGLGKTLQAICVIAGEY---------SRAPSTCP-PSLIVCPPTLTVHWHQEFKKFLVNLPDFNTIVYLGTPMYRQCIFNSLSRYQVVITSYDTLRSDMNLLARPTFPRCGTDVTKGSLMANSNVWNYVVLDEGHLIRNYKSKVAVATRALCARHRLVLTGTPIQNRVGELWSLFDFLMPGLLGTCTEFNRRYGRVLEQNGSNSGRKVDSEAGTLALELLHRQVLPFMLRRVKDDVLQELPPKIMQDYMCTMSPLQLRLYTHCMESQAATDTDFVELVDKSYKENSAINQHRHGFQTMHYLRLVCNHPSLGLTSSHPLYRTLMRELAANNQCLDDINLSGKLVALRQLILDCGVGVSGAGEEELDETSVVASNRLLVFCQSIKMMELVDKMIRNE-IPKATHLRLDGSVPAKDRQQIVEKFSCDAXXXXXXXXXXXXXXXXXXXXANIVIFVEHDWNPMRDLQAMDRAHRIGQKHTVIVYRLITAQSIEEKIMNLQEFKKFLANAVVSKDNNQMASMNTENILEIMNKEANWPTQSPPASANGKQKVVSSVSGGTETQLGSKSVLSKISKADSGERVYDCLDEYDQEYNLDSFV 5515
            GA+E IY + H    G+LPY   +  +++PV L  ++   + +R +AT  F+ L+ L+PLE+   D   L+    + R +   F+  +L+ + + ++    ++  A+LR YQ+EGVNWL FLNRY LHG+L DDMGLGKTLQ IC++A ++         ++ P     PSLIVCPP+L+ HW QE K++    P  N + Y+G P  R  + ++L    +V+TSYD  R+D  +L                   N   WNY VLDEGHLI+N K+K  +A + L + HRL+L+GTPIQN V ELWSLFDFLMPG LGT   F  R+ + +  +  +     + EAG LA+E LH+QVLPF+LRR+K++VL +LPPKI+Q+Y C  S LQ +L+    + +     D V   +K+ KE        H FQ + Y+R +CN P+L +   H  Y  + + LAA +  + D+  + KL ALR L++DCG+GV    E +L   S V+ +R L+FCQ  +M+++V   + N+ +P    LRLDGSV A  RQ IV +F+ D S D+LLLTTS+GGLGLNLT A+ VIFVEHDWNP +D+QAMDRAHRIGQK  V VYRLIT  ++EEKI+NLQ FK  +A+ VV++ N  + +M+T+ +L++ N      T   P+ A G +  +  + G  + + G K  L      D GE   D   +Y +EYNLDSF+
Sbjct: 1202 GAVECIYHLIHVMEDGILPY---VIFLVVPV-LGRMSDSDNEVRLLATTSFATLVKLVPLEAGIPDPPGLSEELLKGRDRERQFMAQMLDVRKVEEFKIPVAI-KAELRPYQQEGVNWLAFLNRYNLHGILCDDMGLGKTLQTICIVASDHHMRAEEFARTQKPEVRKLPSLIVCPPSLSGHWQQELKQYA---PFLNCVAYVGPPAERSRLQSALPNADIVVTSYDICRNDNEVL-------------------NPINWNYCVLDEGHLIKNPKAKATIAVKRLLSNHRLILSGTPIQNNVLELWSLFDFLMPGFLGTEKVFLDRFAKPIAASRFSKSSSKEQEAGALAIEALHKQVLPFLLRRLKEEVLNDLPPKIIQNYYCDPSELQRKLFEDFTKKEQKALQDKVGSTEKADKE--------HIFQALQYMRRLCNSPALVVKEGHKQYNEVQQYLAAKHSNIRDVAHAPKLSALRDLLIDCGIGVDSPSEGDLSGASYVSPHRALIFCQMKEMLDIVQSEVFNKLLPSVQFLRLDGSVEATRRQDIVNRFNTDPSYDVLLLTTSVGGLGLNLTGADTVIFVEHDWNPQKDIQAMDRAHRIGQKKVVNVYRLITRGTLEEKILNLQRFKIDVASTVVNQQNAGLGTMDTDQLLDLFNLGETAETAEKPSDAAGNEVDMVDIDGNVKEK-GKKGWLD-----DLGELWDD--RQYQEEYNLDSFL 1886          

Query:  701 TERERNTEWPWVDFCEELLKNLWDAKWEIRHGAATCLRELIRSQGSIMLPKNANISSTDKFAACHERFQEEIVVRLLCTLTLDQLSDFVSDEMVAPVRESCAQALGVISVHLTRRLVEILANQLLSLLNHDE-------WRVNHXXXXXXXXXXXXRMDLV---EVLLPIIYDPISSHLKGNXXXXXXXXXXXXLMPLFGDCCSNTVAISNEELDTLKTDLWDVLAVRIDCTTSGATCAVLQLLERLYEKCNVVYNQSEDQPMATDRVKALNEYINRLHWCYFNYSDLVRLAAVRTCRAVLQSIGIKVGTILEHGTIXXXXXXXXXXXXIDDNCQVAAEAHSVWNQFIDSL 1723
            TE   N  WP+   C+ L+ +L+D  WEIRHGAA  LRE+IR QG+          S  +    + ++ +++  RLLC L LD+  D++SD +VAP+RE+  Q LG +   L  R V  +   L  ++   +       W V HG ++GL+YL+A R DL+     L+  + + +   L G+ DDDVR  + A L+P+        V      L TL T +WD L+  +    S +T +V+ LL +L     V+     +   A +   +  + + RL+    +    VR A +R     LQ  G      ++  T+      + Q +L++ N  V  ++  VW++ ++SL
Sbjct:  311 TEEGPNPNWPFELMCDILMVDLFDPNWEIRHGAAMALREVIRIQGAGA--GRVQGKSRAENDILNRKWLDDLACRLLCVLMLDRFGDYISDNVVAPIRETVGQTLGALLSQLPSRSVISVYKCLYRIIMQTDLGLERPIWEVCHGGMIGLRYLVAVRKDLLIKDSKLMDGVLEAVMKGL-GDYDDDVRAVSAATLVPI----AEEFVKTRQSTLGTLMTIVWDCLS-NLQDDLSASTGSVMDLLAKLCTFQEVLDAMKAN--AAVNPESSFGKLVPRLYPFLRHTITSVRSAVLRALMTFLQLEGEGTDEWVDGKTV----RLIFQNLLVERNEGVLKQSLQVWSELLNSL 647          

Query: 3374 GAIELIYLVCH---SGLLPYRLAIAVIILPVVLACLNAPFDPLRRVATHVFSXXXXXXXXESSGADLSILTPARQQQRKQHLSFLDSLLNPKLIGQYNAHHSVVSAKLRQYQEEGVNWLGFLNRYGLHGVLADDMGLGKTLQAICVIAGEY---------SRAPSTCP-PSLIVCPPTLTVHWHQEFKKFLVNLPDFNTIVYLGTPMYRQCIFNSLSRYQVVITSYDTLRSDMNLLARPTFPRCGTDVTKGSLMANSNVWNYVVLDEGHLIRNYKSKVAVATRALCARHRLVLTGTPIQNRVGELWSLFDFLMPGLLGTCTEFNRRYGRVLEQNGSNSGRKVDSEAGTLALELLHRQVLPFMLRRVKDDVLQELPPKIMQDYMCTMSPLQLRLYTHCMESQAATDTDFVELVDKSYKENSAINQHRHGFQTMHYLRLVCNHPSLGLTSSHPLYRTLMRELAANNQCLDDINLSGKLVALRQLILDCGVGVSGAGEEELDETSVVASNRLLVFCQSIKMMELVDKMIRNE-IPKATHLRLDGSVPAKDRQQIVEKFSCDAXXXXXXXXXXXXXXXXXXXXANIVIFVEHDWNPMRDLQAMDRAHRIGQKHTVIVYRLITAQSIEEKIMNLQEFKKFLANAVVSKDNNQMASMNTENILEIMNKEANWPTQSPPASANGKQKVVSSVSGGTETQLGSKSVLSKISKADSGERVYDCLDEYDQEYNLDSFV 5515
            GA+E IY + H    G+LPY   +  +++PV L  ++   + +R +AT  F+ L+ L+PLE+   D   L+    + R +   F+  +L+ + + ++    ++  A+LR YQ+EGVNWL FLNRY LHG+L DDMGLGKTLQ IC++A ++         ++ P     PSLIVCPP+L+ HW QE K++    P  N + Y+G P  R  + ++L    +V+TSYD  R+D  +L                   N   WNY VLDEGHLI+N K+K  +A + L + HRL+L+GTPIQN V ELWSLFDFLMPG LGT   F  R+ + +  +  +     + EAG LA+E LH+QVLPF+LRR+K++VL +LPPKI+Q+Y C  S LQ +L+    + +     D V   +K+ KE        H FQ + Y+R +CN P+L +   H  Y  + + LAA +  + D+  + KL ALR L++DCG+GV    E +L   S V+ +R L+FCQ  +M+++V   + N+ +P    LRLDGSV A  RQ IV +F+ D S D+LLLTTS+GGLGLNLT A+ VIFVEHDWNP +D+QAMDRAHRIGQK  V VYRLIT  ++EEKI+NLQ FK  +A+ VV++ N  + +M+T+ +L++ N      T   P+ A G +  +  + G  + + G K  L      D GE   D   +Y +EYNLDSF+
Sbjct: 1202 GAVECIYHLIHVMEDGILPY---VIFLVVPV-LGRMSDSDNEVRLLATTSFATLVKLVPLEAGIPDPPGLSEELLKGRDRERQFMAQMLDVRKVEEFKIPVAI-KAELRPYQQEGVNWLAFLNRYNLHGILCDDMGLGKTLQTICIVASDHHMRAEEFARTQKPEVRKLPSLIVCPPSLSGHWQQELKQYA---PFLNCVAYVGPPAERSRLQSALPNADIVVTSYDICRNDNEVL-------------------NPINWNYCVLDEGHLIKNPKAKATIAVKRLLSNHRLILSGTPIQNNVLELWSLFDFLMPGFLGTEKVFLDRFAKPIAASRFSKSSSKEQEAGALAIEALHKQVLPFLLRRLKEEVLNDLPPKIIQNYYCDPSELQRKLFEDFTKKEQKALQDKVGSTEKADKE--------HIFQALQYMRRLCNSPALVVKEGHKQYNEVQQYLAAKHSNIRDVAHAPKLSALRDLLIDCGIGVDSPSEGDLSGASYVSPHRALIFCQMKEMLDIVQSEVFNKLLPSVQFLRLDGSVEATRRQDIVNRFNTDPSYDVLLLTTSVGGLGLNLTGADTVIFVEHDWNPQKDIQAMDRAHRIGQKKVVNVYRLITRGTLEEKILNLQRFKIDVASTVVNQQNAGLGTMDTDQLLDLFNLGETAETAEKPSDAAGNEVDMVDIDGNVKEK-GKKGWLD-----DLGELWDD--RQYQEEYNLDSFL 1886          

Query:  701 TERERNTEWPWVDFCEELLKNLWDAKWEIRHGAATCLRELIRSQGSIMLPKNANISSTDKFAACHERFQEEIVVRLLCTLTLDQLSDFVSDEMVAPVRESCAQALGVISVHLTRRLVEILANQLLSLLNHDE-------WRVNHXXXXXXXXXXXXRMDLV---EVLLPIIYDPISSHLKGNXXXXXXXXXXXXLMPLFGDCCSNTVAISNEELDTLKTDLWDVLAVRIDCTTSGATCAVLQLLERLYEKCNVVYNQSEDQPMATDRVKALNEYINRLHWCYFNYSDLVRLAAVRTCRAVLQSIGIKVGTILEHGTIXXXXXXXXXXXXIDDNCQVAAEAHSVWNQFIDSL 1723
            TE   N  WP+   C+ L+ +L+D  WEIRHGAA  LRE+IR QG+          S  +    + ++ +++  RLLC L LD+  D++SD +VAP+RE+  Q LG +   L  R V  +   L  ++   +       W V HG ++GL+YL+A R DL+     L+  + + +   L G+ DDDVR  + A L+P+        V      L TL T +WD L+  +    S +T +V+ LL +L     V+     +   A +   +  + + RL+    +    VR A +R     LQ  G      ++  T+      + Q +L++ N  V  ++  VW++ ++SL
Sbjct:  311 TEEGPNPNWPFELMCDILMVDLFDPNWEIRHGAAMALREVIRIQGAGA--GRVQGKSRAENDILNRKWLDDLACRLLCVLMLDRFGDYISDNVVAPIRETVGQTLGALLSQLPSRSVISVYKCLYRIIMQTDLGLERPIWEVCHGGMIGLRYLVAVRKDLLIKDSKLMDGVLEAVMKGL-GDYDDDVRAVSAATLVPI----AEEFVKTRQSTLGTLMTIVWDCLS-NLQDDLSASTGSVMDLLAKLCTFQEVLDAMKAN--AAVNPESSFGKLVPRLYPFLRHTITSVRSAVLRALMTFLQLEGEGTDEWVDGKTV----RLIFQNLLVERNEGVLKQSLQVWSELLNSL 647          

Query: 3374 GAIELIY---LVCHSGLLPYRLAIAVIILPVVLACLNAPFDPLRRVATHVFSXXXXXXXXESSGADLSILTPARQQQRKQHLSFLDSLLNPKLIGQYNAHHSVVSAKLRQYQEEGVNWLGFLNRYGLHGVLADDMGLGKTLQAICVIAG---------EYSRA-PSTCPPSLIVCPPTLTVHWHQEFKKFLVNLPDFNTIVYLGTPMYRQCIFNSLSRYQVVITSYDTLRSDMNLLARPTFPRCGTDVTKGSLMANSNVWNYVVLDEGHLIRNYKSKVAVATRALCARHRLVLTGTPIQNRVGELWSLFDFLMPGLLGTCTEFNRRYGRVLEQNGSNSGRKVDSEAGTLALELLHRQVLPFMLRRVKDDVLQELPPKIMQDYMCTMSPLQLRLYTHCMESQAATDTDFVELVDKSYKENSAINQHRHGFQTMHYLRLVCNHPSLGLTSSHPLYRTLMRELAANNQCLDDINLSGKLVALRQLILDCGVGVSGAGEEELDETS----------VVASNRLLVFCQSIKMMELVDK-MIRNEIPKATHLRLDGSVPAKDRQQIVEKFSCDAXXXXXXXXXXXXXXXXXXXXANIVIFVEHDWNPMRDLQAMDRAHRIGQKHTVIVYRLITAQSIEEKIMNLQEFKKFLANAVVSKDNNQMASMNTENILEIMNKEANWPTQSPPASANGKQKVVSSVSGGTETQLGSKSVLSKISKADSGE--RVYDCLDEYDQEYNLDSFV 5515
            G+ ELIY   L   + +LPY   +  +I+P+ L  ++   + +R +AT  F+ ++ L+PLE+  AD   L       R++   F+  +++P     +    ++  A LR+YQ++GVNWL FLN+Y LHG+L DDMGLGKTLQ IC+IA          E +R+  S   PSLI+CPP+LT HW  EF ++    P    +VY G P  R  +   LS   +++TSYD  R+D+ +L                   N   +NY VLDEGH+I+N +SK+A A + + A HRL+LTGTPIQN V ELWSLFDFLMPG LGT   F  R+ + +  + ++     + EAG LALE LH+QVLPFMLRR+K+DVL +LPPKI+QDY C +  LQ +LY    + Q         +V+K  + +   +  +H FQ + Y+R +CNHP+L L+ +HP    +   L      L DI  + KL ALR L+ +CG+     GEE++D+ +          V++ +R L+FCQ   M+++V+  + +  +P  T++RLDGS+  +DRQ++V KF+ D SID LLLTT +GGLGLNLT A+ VIFVEHDWNPM DLQAMDRAHRIGQK  V VYR+IT  ++EEKIM LQ+FK  +A+ VV++ N+ +ASM+T  +L++ + + N  +Q      NG     S  + G E  + +++ L+  +K   GE   ++D   +Y++EYNLD+F+
Sbjct: 1170 GSTELIYHLSLSMETDVLPY---VIFLIVPL-LGRMSDSNEDVRNLATTTFASIIKLVPLEAGIADPKGLPEELVASRERERDFIQQMMDPSKAKPFKLPIAI-KATLRKYQQDGVNWLAFLNKYHLHGILCDDMGLGKTLQTICIIASDQYLRKEDYEKTRSVESRALPSLIICPPSLTGHWENEFDQYA---PFLKVVVYAGGPTVRLTLRPQLSDADIIVTSYDVARNDLAVL-------------------NKTEYNYCVLDEGHIIKNSQSKLAKAVKEITANHRLILTGTPIQNNVLELWSLFDFLMPGFLGTEKMFQERFAKPIAASRNSKTSSKEQEAGVLALEALHKQVLPFMLRRLKEDVLSDLPPKIIQDYYCELGDLQKQLYMDFTKKQK-------NVVEKDIENSEIADGKQHIFQALQYMRKLCNHPALVLSPNHPQLAQVQDYLKQTGLDLHDIINAPKLSALRTLLFECGI-----GEEDIDKKASQDQNFPIQNVISQHRALIFCQLKDMLDMVENDLFKKYMPSVTYMRLDGSIDPRDRQKVVRKFNEDPSIDCLLLTTKVGGLGLNLTGADTVIFVEHDWNPMNDLQAMDRAHRIGQKKVVNVYRIITKGTLEEKIMGLQKFKMNIASTVVNQQNSGLASMDTHQLLDLFDPD-NVTSQDNEEKNNGD----SQAAKGME-DIANETGLTGKAKEALGELKELWDP-SQYEEEYNLDTFI 1863          

Query:   86 SRLDKLFELLESNH-QNIRNAAAIQIGQLSANNQVNISALLAKLLPYAKHKIWVVRIAASDAVRHIGNNAKLW-------VPGTS---------------------ESNVTNVSNLI-------NLENLNLHDILKIGTRLYSRDFKDLD-----EANTNQNINRDELARHLGFLIPDECEIKNLITVKDCELVESKSENKMSVELAVMK------SMENSPKKPVKRPHEEVQDV--------------------NEPGTKMKCVEK--------------IGNETERERNTEWPWVDFCEELLKNLWDAKWEIRHGAATCLRELIRSQGSIMLPKNANISSTDKFAACHERFQEEIVVRLLCTLTLDQLSDFVSDEMVAPVRESCAQALGVISVHLTRRLVEILANQLLSLLNHDE---------WRVNHXXXXXXXXXXXXRMD------LVEVLLPIIYDPISSHLKGNXXXXXXXXXXXXLMPLFGDCCSNTVAISNEELDTLKTDLWDVLAVRIDCTTSGATCAVLQLLERL---YEKCNVVYNQSEDQP 1456
            SRLD+   L+E+   Q +RN AA Q+G L+  +  +I +LL+++ P+   K W  R+ A+ AV  I  +A  W       V GT+                     E+   N  NL+       +L +  L++ILK G  L +    D +     + N  +    D++ +    L   +   +N             + NK S  +  M       S +N+PK PV      V                       N+   K++  E+              +  + E      W +    E LL NL    WEIRHGAA  LREL++     +     N    +     + R  E++  RLL    LD+  D+V D +VAPVRES AQ L  + +HL   L   + N L  L+  D          W   HG LLG++Y ++ + +      L+E ++ I+   ++       DDDV+  A + L P+     S  V ++N  ++ L T +W +LA R+D   S +  +++ LL +L    E  +++ N++ + P
Sbjct:    6 SRLDRQVILIETGSTQVVRNMAADQMGDLAKQHPEDILSLLSRVYPFLLVKKWETRVTAARAVGGIVAHAPSWDPNESDLVGGTNEGSPLDNAQVKLEHEMKIKLEEATQNNQLNLLQEDHHLSSLSDWKLNEILKSGKVLLASSMNDYNVLGKADDNIRKQAKTDDIKQETSMLNASDKANEN-----------KSNANKKSARMLAMARRKKKMSAKNTPKHPVDITESSVSKTLLNGKNMTNSAASLATSPTSNQLNPKLEITEQADESKLMIESTVRPLLEQHEIVAGLVWQFQGIYELLLDNLMSENWEIRHGAALGLRELVKKHAYGVSRVKGNTREENNLR--NSRSLEDLASRLLTVFALDRFGDYVYDTVVAPVRESVAQTLAALLIHLDSTLSIKIFNCLEQLVLQDPLQTGLPNKIWEATHGGLLGIRYFVSIKTNFLFAHGLLENVVRIVLYGLN-----QSDDDVQSVAASILTPI----TSEFVKLNNSTIEILVTTIWSLLA-RLDDDISSSVGSIMDLLAKLCDHQEVLDILKNKALEHP 538          

Query: 3374 GAIELIYLVCHS---GLLPYRLAIAVIILPVVLACLNAPFDPLRRVATHVFSXXXXXXXXESSGADLSILTPARQQQRKQHLSFLDSLLNPKLIGQYNAHHSVVSAKLRQYQEEGVNWLGFLNRYGLHGVLADDMGLGKTLQAICVIAGE-YSR----APSTCP-----PSLIVCPPTLTVHWHQEFKKFLVNLPDFNTIVYLGTPMYRQCIFNSLSRYQVVITSYDTLRSDMNLLARPTFPRCGTDVTKGSLMANSNVWNYVVLDEGHLIRNYKSKVAVATRALCARHRLVLTGTPIQNRVGELWSLFDFLMPGLLGTCTEFNRRYGRVLEQNGSNSGRKVDSEAGTLALELLHRQVLPFMLRRVKDDVLQELPPKIMQDYMCTMSPLQLRL---YTHCMESQAATDTDFVELVDKSYKENSAINQHRHGFQTMHYLRLVCNHPSLGLTSSHPLYRTLMRELAANNQCLDDINLSGKLVALRQLILDCGVGVSGAGEEELDE--TSVVASNRLLVFCQSIKMMELVDK-MIRNEIPKATHLRLDGSVPAKDRQQIVEKFSCDAXXXXXXXXXXXXXXXXXXXXANIVIFVEHDWNPMRDLQAMDRAHRIGQKHTVIVYRLITAQSIEEKIMNLQEFKKFLANAVVSKDNNQMASMNTENILEIMNKEANWPTQSPPASANGKQKVVSSVSGGTETQLGSKSVLSKISKADSGERVYDCLDE--YDQEYNLDSFV 5515
            GAIE IY V       +LPY   I  +I+P++    +A  D +R +AT  F+ L+ L+PLE+   D   L       R++   FL+ +LNP  +  ++    + SA LR+YQ+EGVNWL FLN+Y LHG+L DDMGLGKTLQ IC++A + Y+R      S  P     PSLIVCP TL  HW QE   +    P      Y+G P  R  I + + +  VV+TSYD  R+D++ L +                     WNY VLDEGH+I+N ++K+  A ++L + HRL+L+GTPIQN V ELWSLFDFLMPG LGT   F  R+ R +  +        + E GTLALE +H+QVLPFMLRR+K+DVL +LPPKI+QDY C MS LQ +L   +   +      + D  E    + K+ S   Q  H FQ + Y+R +CNHP+L LT  HP    ++++LA  N  L D+  + KL AL QL+ DCG+G S      +D   T+ V+ +R+L+FCQ   M+++V+K +++  +P  T++RLDGSV    RQ+ V KF+ D SID+LLLTT +GGLGLNLT A+ VIFVEHDWNPMRDLQAMDRAHRIGQK  V VYRLIT   +EEKIM LQ FK  +A+ VV++ N  ++S+ T+ IL++ N  A+            +Q+ V ++    E++  +   LS  SK  + E + +  DE  YD E+NLD F+
Sbjct: 1256 GAIECIYHVVQRLGVRILPY---ILYLIIPLLGRMSDADQD-VRVLATTSFATLVKLVPLEAGLPDPPDLPQYLLDSREKERKFLEQMLNPSKVEAFSIPVPI-SADLRKYQQEGVNWLAFLNKYELHGILCDDMGLGKTLQTICIVASDHYNRQKLFEESGSPKFAHVPSLIVCPSTLAGHWQQELSTYA---PFLKVSAYVGPPAERAKIRSKMKKSDVVVTSYDICRNDVDELVKID-------------------WNYCVLDEGHVIKNARAKLTKAVKSLRSYHRLILSGTPIQNNVLELWSLFDFLMPGFLGTEKTFQERFVRPIAASRDAKSSSKERERGTLALEAIHKQVLPFMLRRLKEDVLADLPPKIIQDYYCDMSDLQRKLLNDFVSQLNINEELEDDETEKTQGTRKKKS---QKAHIFQALQYMRKLCNHPALILTEKHPKRNAIVKQLAKENSGLHDLKHAPKLTALGQLLRDCGLGNSSVNSNGIDSALTNAVSEHRVLIFCQLKDMLDMVEKDLLQATMPDVTYMRLDGSVEPTKRQEAVTKFNNDPSIDVLLLTTHVGGLGLNLTGADTVIFVEHDWNPMRDLQAMDRAHRIGQKKVVNVYRLITRGCLEEKIMGLQRFKMNVASTVVNQQNAGLSSIGTDQILDLFNTTAD------------EQQTVQNID-KEESEDAAGRGLSGTSKK-ALEGLPEMWDESQYD-EFNLDGFI 1945          

Query:  725 WPWVDFCEELLKNLWDAKWEIRHGAATCLRELIRSQGSIMLPKNANISSTDKFAACHERFQEEIVVRLLCTLTLDQLSDFVSDEMVAPVRESCAQALGVISVHLTRRLVEILANQLLSLLNHDE 1096
            WP+    E LL +++D  WEIRHGA   LRE+IR  G     +    S  +     ++++ ++++ R+ C   LD+  D+++D++VAP+RES +Q LGV  +++    V  +   L SL+  +E
Sbjct:  359 WPFETLVELLLIDMFDPSWEIRHGACMGLREIIRYAG-FGYGRVVGKSEAEN-EQLNKKYFDDLLCRIACVFALDRFGDYLADQVVAPIRESVSQVLGVALIYVPNDSVFSMYKVLHSLVFQNE 480          

Query:  623 KRPHEEVQDVNEPGTKMKCVE-KIGNET------ERERNTEWPWVDFCEELLKNLWDAKWEIRHGAATCLRELIRSQGSIMLPKNANIS---STDKFAACHERFQEEIVVRLLCTLTLDQLSDFVSDEMVAPVRESCAQALGVISVHLTRRLVEILANQLLSLLNHDEWRVNHXXXXXXXXXXXXRMDLVEVLLPIIYDPISSHLKGNXXXXXXXXXXXXLMPLFGDCCSNTVAISNEELDTLKTDLWDVLAVRIDCTTS-----GATCAVLQLLERLYEKCNVVYNQSEDQPMATDRVKALNEYINRLHWCYFNYSDLVRLAAVRTCRAVLQSIG-IKVGTIL--EHGTIXXXXXXXXXXXXIDDNCQVAAEAHSVWNQFID--SLPEQLLARVSCERLEIWMCSAMQPARLSYTPGSILMPDYIIXXXXXXXXXXXXDGLDEDDGNKHHILT--EFYIGGRESFITDGSSAARDDLVXXXXXXXXXXXXXXXXXFIFHEAGI---RNILISI-----IAQIHLKDRLAVQRFVASMILAYWDPDHLLAMRNLNDCSLSP--LQSQLLTALEEPIYYQEILSQFKQMHKACRDLILIYIEREIPLPPSIMNAVGPNASPVSIALNISQCQSLISSEMCSLCPPESMTTFSCATAAVDTCAQQHATLCRLVD--------------IAVGRALLQWGWXXXXXXXXXXXXXSAVRSETCVTLQTEACIALAQLVVDHNSQTRLLAPVTKLVKNLIQYQSEAIDSLATMQ--PHEVEQGEIVAIYKTSQLGREAFPRQEDNG--------TAVAID------NDVM----IKLRGSRLALEKIYSRFVSSSESDLDHSF-LMEIIYHAXXXXXXXXXXXXRDRHHDNNSILVALRAMNTCLPFIKHASNRFQKISLACYAQSVFQSGLSHIDPIIRHWSARVLAMLVMPQSAADNXXXXXXXXXXXXXXXXXXXXXMTLNEKLCYGAIELIYLVCHSGLLPYRLAIAVIILPVVLACLNAPFDP---LRRVATHVFSXXXXXXXX-----ESSGADLSILTPARQQQRK---QHLS--------------------FLDSLLNPKLIGQYNAHHSVVSAKLRQYQEEGVNWLGFLNRYGLHGVLADDMGLGKTLQAICVIAGEYS---------RAPSTCP-PSLIVCPPTLTVHWHQEFKKFLVNLPDFNTIVYLGTPMYRQCIFNSLSRYQVVITSYDTLRSDMNLLARPTFPRCGTDVTKGSLMANSNVWNYVVLDEGHLIRNYKSKVAVATRALCARHRLVLTGTPIQNRVGELWSLFDFLMPGLLGTCTEFNRRYGRVLEQNGSNSGRKVDSEAGTLALELLHRQVLPFMLRRVKDDVLQELPPKIMQDYMCTMSPLQLRLYTHCMESQAATDTDFVELVDKSYKENSAINQHRHGFQTMHYLRLVCNHPSLGLTSSHPLYRTLMRELAANNQCLDDINLSGKLVALRQLILDCGVGVSGAGEEELDETSVVASNRLLVFCQSIKMMELVDK-MIRNEIPKATHLRLDGSVPAKDRQQIVEKFSCDAXXXXXXXXXXXXXXXXXXXXANIVIFVEHDWNPMRDLQAMDRAHRIGQKHTVIVYRLITAQSIEEKIMNLQEFKKFLANAVVSKDNNQMASMNTENILEIMN 5314
            ++  E + +  EP  K   VE K+ +ET      +   + +WP   FC++L ++L+ + WE RHGAAT LRE++   G     K A  S   + D+    H+ + +++ +RLLC L LD+  DFVSD +VAPVRE+CAQ L  +   +  +      N LL LLN + W   HG LLGLKYLLA R D+V  LL   +  I   L  +  DDV   A +AL+P+        V +  + ++ + T LWD+LA + +  ++     G   A+L L E           Q+   P      + L+E + +L W + ++S     ++VR  +A LQ++G +  G  +  E   +   L  + QRVL++  C V   A  VWN+ I    L E LLA  +C  +  W+C +MQP R+ Y P   +         A +      +G++  D    H +T  + YIGG E+       A R+   ++ R  A ++L  L    I    G+   ++I + +     I  +HL+ + A+QR +A +++A W         +L+  ++ P  L+  L   L E +Y+ EI + F ++ +  +D I +    ++P           N   V   L + Q + L  +E+      + +  F      +D+  ++   L   V                A+  A + +  LP KLTP++KPL+ ++R E    LQ  A   LA L+     + R   P  K++ NL  +     +   T+   P  V QG +    +     + A+ R    G        T + ++      +DV     I+ RG+ LA  +I S F +     L   + LM     A +     +      +  D   +L  L+ M  C   I H   R      +     V    LSH    +RH SAR LA      S           +  +++   L  L  T NE    GA+E I  +  +     +  I   ++ +V+  L    D    +R + TH F+ L+ L+PL     E  G  LS+L   R+++R+   Q LS                    FL  LL+P  I  Y      + A+LR YQ+ GVNWL FLN+Y LHG+L DDMGLGKTLQ+IC++AG++          RAP   P PSL++CPPTLT HW  E +KFL +      + Y G+P+ R+ +     +Y +++ SYD +R D+   +                      WNY++LDEGH+I+N K++ ++A + L A+HRL+L+GTPIQN V ELWSLFDFLMPG LGT  +F  RY R +  +        + EAG LA+E LHRQVLPF+LRR+K+DVL +LPPKI QDY C +S LQ RLY     SQA      +E    +    S++  + H FQ + YL+ VCNHP L LT SHP Y  +  +L      L++I+ S KL AL QL+ DCG+GV+     EL    V+  +R LVFCQ   M+ +++  + +  +P  T+LRLDGSVPA  RQ +V +F+ D SID+LLLTT +GGLGLNLT A+ VIFVEHDWNPM+DLQAMDRAHRIGQ+  V VYRLIT  ++EEKIM LQ+FK   AN V+S +N+++ +M TE +L++ +
Sbjct:  148 QKSREPIDEEYEPDKKKNRVEDKVKDETALTIDIDNGDSGDWPLEMFCDQLSQDLFSSSWEARHGAATALREILTVHG-----KGAGKSVYLTADQIIEYHQAWLDDMAIRLLCVLALDKFGDFVSDSVVAPVRETCAQCLCAVLKLMNEKGCNTALNILLQLLNQEGWEARHGGLLGLKYLLAVREDMVHALLTGAFPSIMKGL-SDPVDDVGAVAASALIPI----VEKLVKLVPKSIELVVTKLWDLLAEQDELASACNSFMGLLAAILSLPE----------AQTLLPP------QPLSEVVPKL-WPFLSHST----SSVR--KATLQTLGTLTDGNTMQWEAQLLQDALRHVYQRVLVEPLCDVRRLAELVWNKLIKHAGLVELLLA--TCPFVSAWLCLSMQPIRIPYDPNLFIF--------AKSQRKQKVEGINSFD----HTVTPVKLYIGGSET----TPLATRETNAIKVRCMAARMLGLLSCYVIQKAPGVDYTKDIEVPLDCYIKILMVHLQSKSALQRMMAGLVIAEW--------ASLDAETICPELLKQILHKCLSECVYFDEIAASFTKLAQETKDFIAMLKHYKVP--------TDVNGDSV---LTLDQMKLLTGTEV-----QQVLLRFKLKQKILDSLEERRRGLHDSVSQTSQDQYMLSVSTLAALSGATVMFKALPEKLTPVVKPLMESIRREGDEQLQHIAAKRLAYLL--DQCRLRNSCPNDKILTNLCMFLRGDPEFTPTISKIPENVCQGIVTLDNQQRNAEKAAYRRSNSTGRGPGRPPATDIPLEELFKENDDVQKSNHIQRRGATLAFTEIVSYFGNELPEKLPKMWSLMVGQLTATVDPENFNVQALVGKKDDAEQLLWMLQVMEVCALHI-HPDLREMLFDNSLKRFCVL---LSHPYKAVRHLSARCLAAFAKIDSVP---------VMELIVSKVLPMLGATTNETDRQGAVEAIACIVEA----LQFDIVPYVVLLVVPLLGRMSDQNQCVRLMGTHSFATLVQLMPLDGGIPEPPGLKLSVLCAKREKEREFLSQLLSPEPPGLKLSVLCAKREKEREFLSQLLSPSSIPDYQIPVP-IDAELRTYQQAGVNWLAFLNKYKLHGILCDDMGLGKTLQSICILAGDHYHREQNYKLIRAPDCAPLPSLVICPPTLTGHWTYEVEKFL-SRKYLRPLQYNGSPVEREKLRYRFDKYNLIVASYDIVRKDIIFFSHIK-------------------WNYIILDEGHVIKNGKTRTSIAIKQLIAQHRLILSGTPIQNNVLELWSLFDFLMPGFLGTEKQFTARYSRPILASRDPKCSSKEQEAGALAMEALHRQVLPFLLRRMKEDVLDDLPPKITQDYYCELSTLQERLYDDFSRSQAHQT---LEESLSTGATASSMQGNTHIFQALRYLQNVCNHPKLVLTPSHPQYNKISLQLQNEGTLLENIHHSAKLPALMQLLQDCGIGVTETQSTEL----VINQHRALVFCQLKAMLNIIENDLFKKHMPGVTYLRLDGSVPASQRQVLVTRFNNDPSIDVLLLTTQVGGLGLNLTGADTVIFVEHDWNPMKDLQAMDRAHRIGQRKVVNVYRLITRSTLEEKIMGLQKFKVQTANTVISGENSRLETMATEQLLDLFS 1698          

Query: 3374 GAIELIYLVCHS---GLLPYRLAIAVIILPVVLACLNAPFDPLRRVATHVFSXXXXXXXXESSGADLSILTPARQQQRKQHLSFLDSLLNPKLIGQYNAHHSVVSAKLRQYQEEGVNWLGFLNRYGLHGVLADDMGLGKTLQAICVIAG-------EYSR---APSTCPPSLIVCPPTLTVHWHQEFKKFLVNLPDFNTIVYLGTPMYRQCIFNSLSRYQVVITSYDTLRSDMNLLARPTFPRCGTDVTKGSLMANSNVWNYVVLDEGHLIRNYKSKVAVATRALCARHRLVLTGTPIQNRVGELWSLFDFLMPGLLGTCTEFNRRYGRVLEQNGSNSGRKVDSEAGTLALELLHRQVLPFMLRRVKDDVLQELPPKIMQDYMCTMSPLQLRLYTHCMESQAATDTD----FVELVDKSYKENSAINQHRHGFQTMHYLRLVCNHPSLGLTSSHPLYRTLMRELAANNQCLDDINLSGKLVALRQLILDCGVGVSGAGEEELDETSVVASNRLLVFCQSIKMMELVD-KMIRNEIPKATHLRLDGSVPAKDRQQIVEKFSCDAXXXXXXXXXXXXXXXXXXXXANIVIFVEHDWNPMRDLQAMDRAHRIGQKHTVIVYRLITAQSIEEKIMNLQEFKKFLANAVVSKDNNQMASMNTENILEIMNKEANWPTQSPPASANGKQKVVSSVSGGTETQLGSKSVLSKISKADSGERVYDCLDEYDQEYNLDSFV 5515
            GAIE +  +      G++PY   I ++++PV L  ++   D +R +AT  F+ L+ L+PLE+   D   ++    + + +   FL+ LL+ K +  Y      + A+LR+YQ+EGVNWL FLN+Y LHG+L DDMGLGKTLQ+IC++AG       EY+R   A S   PSL+VCPPTLT HW  E  KF  +    N + Y G P  R  +   + R+ +++ SYD +R+D++      F                   NY +LDEGH+I+N K+K++ A + L A +R++L+GTPIQN V ELWSLFDFLMPG LGT  +F  RYG+ +  +        + EAG LA+E LHRQVLPF+LRR+K+DVLQ+LPPKI+QDY C +S LQ++LY    +S+A  D D       L +++  E   +    H FQ + YLR +CNHP+L LT+ HP ++ +  +L A N  L DI  + KL AL+QL+LDCG+G  G+ E   +  ++VA +R+L+FCQ   M+++V+  +++  +P  T+LRLDGS+PA  R  IV +F+ D SID+LLLTT +GGLGLNLT A+ V+FVEHDWNPM+DLQAMDRAHRIGQK  V VYRLIT  ++EEKIM LQ+FK  +AN V+S++N  + SM T+ +L++   + +  T+        K    +SVSG T      KSVL  + +      ++D  D+YD EY+L+ F+
Sbjct:   47 GAIEALGAIMEQLDVGIIPY---IVLLVVPV-LGRMSDQTDSVRFMATQCFATLIRLMPLEAGIPDPPNMSEDLIKIKAKERHFLEQLLDGKKLENYKIP-VPIKAELRKYQQEGVNWLAFLNKYKLHGILCDDMGLGKTLQSICILAGDHYLRAQEYARTKVADSIPLPSLVVCPPTLTGHWVDEVGKF-CSKEFLNPLHYTGPPTERARLQQHVKRHNLIVASYDVVRNDIDFFRNIKF-------------------NYCILDEGHVIKNGKTKLSKAIKQLAANYRIILSGTPIQNNVLELWSLFDFLMPGFLGTERQFAARYGKPILASRDARSSSREQEAGVLAMEALHRQVLPFLLRRMKEDVLQDLPPKIIQDYYCILSSLQVQLYEDFAKSRAKCDVDETVSAASLTEET--EKPKLKATGHVFQALQYLRKLCNHPALVLTAHHPEHKRITEKLGAENSSLHDIQHAPKLSALKQLLLDCGLGNGGSPESGTE--TIVAQHRILIFCQLKSMLDIVEHDLLKPHLPSVTYLRLDGSIPAGQRHSIVSRFNNDPSIDVLLLTTHVGGLGLNLTGADTVVFVEHDWNPMKDLQAMDRAHRIGQKRVVNVYRLITRGTLEEKIMGLQKFKMNIANTVISQENTSLQSMGTDQLLDLFTLDKDGKTE--------KSDGATSVSGKTSM----KSVLENLGE------LWD-QDQYDSEYSLEKFM 730          

Query: 3410 GLLPYRLAIAVIILPVVLACLNAPFDPLRRVATHVFSXXXXXXXXESSGADLSILTPARQQQRKQHLSFLDSLLNPKLIGQYNAHHSVVSAKLRQYQEEGVNWLGFLNRYGLHGVLADDMGLGKTLQAICVIAG-------EYSRAP-STCPP--SLIVCPPTLTVHWHQEFKKFLVNLPDFNTIVYLGTPMYRQCIFNSLSRYQVVITSYDTLRSDMNLLARPTFPRCGTDVTKGSLMANSNVWNYVVLDEGHLIRNYKSKVAVATRALCARHRLVLTGTPIQNRVGELWSLFDFLMPGLLGTCTEFNRRYGRVLEQNGSNSGRKVDSEAGTLALELLHRQVLPFMLRRVKDDVLQELPPKIMQDYMCTMSPLQLRLYTHCMESQAATDTDFVELVDKSY----KENSAINQHRHGFQTMHYLRLVCNHPSLGLTSSHPLYRTLMRELAANNQCLDDINLSGKLVALRQLILDCGVGVSGAGEEELDETSVVASNRLLVFCQSIKMMELVD-KMIRNEIPKATHLRLDGSVPAKDRQQIVEKFSCDAXXXXXXXXXXXXXXXXXXXXANIVIFVEHDWNPMRDLQAMDRAHRIGQKHTVIVYRLITAQSIEEKIMNLQEFKKFLANAVVSKDNNQMASMNTENILEIMNKEANWPTQSPPASANGKQKVVSSVSGGTETQLGSKSVLSKISKADSGERVYDCLDEYDQEYNLDSFV 5515
            G++PY   I ++++PV L  ++   D +R +AT  F+ L+ L+PLE+   D   ++    Q + +   FL+ LL+ K +  Y      ++A+LR+YQ++GVNWL FLN+Y LHG+L DDMGLGKTLQ+IC++AG       EY+R+  + C P  SL+VCPPTLT HW  E  KF  +    N + Y G P  R  + + + R+ +++ SYD +R+D++      F                   NY +LDEGH+I+N K+K++ A + L A +R++L+GTPIQN V ELWSLFDFLMPG LGT  +F  RYG+ +  +        + EAG LA++ LHRQVLPF+LRR+K+DVLQ+LPPKI+QDY CT+SPLQ++LY    +S+A  D D  E V  +      E   +    H FQ + YLR +CNHP+L LT  HP ++T   +LA  N  L DI  + KL AL+QL+LDCG+G +G+  E   E SVVA +R+L+FCQ   M+++V+  +++  +P  T+LRLDGS+P   R  IV +F+ D SID+LLLTT +GGLGLNLT A+ V+FVEHDWNPMRDLQAMDRAHRIGQK  V VYRLIT  ++EEKIM LQ+FK  +AN V+S++N+ + SM T+ +L++   + +   +    S +GK  +              KS+L  +S       ++D  ++YD EY+L++F+
Sbjct:   29 GIVPY---IVLLVVPV-LGRMSDQTDSVRFMATQCFATLIRLMPLEAGIPDPPNMSAELIQLKAKERHFLEQLLDGKKLENYKIP-VPINAELRKYQQDGVNWLAFLNKYKLHGILCDDMGLGKTLQSICILAGDHCHRAQEYARSKLAECMPLPSLVVCPPTLTGHWVDEVGKF-CSREYLNPLHYTGPPTERIRLQHQVKRHNLIVASYDVVRNDIDFFRNIKF-------------------NYCILDEGHVIKNGKTKLSKAVKQLTANYRIILSGTPIQNNVLELWSLFDFLMPGFLGTERQFAARYGKPILASRDARSSSREQEAGVLAMDALHRQVLPFLLRRMKEDVLQDLPPKIIQDYYCTLSPLQVQLYEDFAKSRAKCDVD--ETVSSATLSEETEKPKLKATGHVFQALQYLRKLCNHPALVLTPQHPEFKTTAEKLAVQNSSLHDIQHAPKLSALKQLLLDCGLG-NGSTSESGTE-SVVAQHRILIFCQLKSMLDIVEHDLLKPHLPSVTYLRLDGSIPPGQRHSIVSRFNNDPSIDVLLLTTHVGGLGLNLTGADTVVFVEHDWNPMRDLQAMDRAHRIGQKRVVNVYRLITRGTLEEKIMGLQKFKMNIANTVISQENSSLQSMGTDQLLDLFTLDKDGKAEKADTSTSGKASM--------------KSILENLSD------LWD-QEQYDSEYSLENFM 695          

Query: 3410 GLLPYRLAIAVIILPVVLACLNAPFDPLRRVATHVFSXXXXXXXXESSGADLSILTPARQQQRKQHLSFLDSLLNPKLIGQYNAHHSVVSAKLRQYQEEGVNWLGFLNRYGLHGVLADDMGLGKTLQAICVIAG-------EYSRAP-STCPP--SLIVCPPTLTVHWHQEFKKFLVNLPDFNTIVYLGTPMYRQCIFNSLSRYQVVITSYDTLRSDMNLLARPTFPRCGTDVTKGSLMANSNVWNYVVLDEGHLIRNYKSKVAVATRALCARHRLVLTGTPIQNRVGELWSLFDFLMPGLLGTCTEFNRRYGRVLEQNGSNSGRKVDSEAGTLALELLHRQVLPFMLRRVKDDVLQELPPKIMQDYMCTMSPLQLRLYTHCMESQAATDTDFVELVDKSY----KENSAINQHRHGFQTMHYLRLVCNHPSLGLTSSHPLYRTLMRELAANNQCLDDINLSGKLVALRQLILDCGVGVSGAGEEELDETSVVASNRLLVFCQSIKMMELVD-KMIRNEIPKATHLRLDGSVPAKDRQQIVEKFSCDAXXXXXXXXXXXXXXXXXXXXANIVIFVEHDWNPMRDLQAMDRAHRIGQKHTVIVYRLITAQSIEEKIMNLQEFKKFLANAVVSKDNNQMASMNTENILEIMNKEANWPTQSPPASANGKQKVVSSVSGGTETQLGSKSVLSKISKADSGERVYDCLDEYDQEYNLDSFV 5515
            G++PY   I ++++PV L  ++   D +R +AT  F+ L+ L+PLE+   D   ++    Q + +   FL+ LL+ K +  Y      ++A+LR+YQ++GVNWL FLN+Y LHG+L DDMGLGKTLQ+IC++AG       EY+R+  + C P  SL+VCPPTLT HW  E  KF  +    N + Y G P  R  + + + R+ +++ SYD +R+D++      F                   NY +LDEGH+I+N K+K++ A + L A +R++L+GTPIQN V ELWSLFDFLMPG LGT  +F  RYG+ +  +        + EAG LA++ LHRQVLPF+LRR+K+DVLQ+LPPKI+QDY CT+SPLQ++LY    +S+A  D D  E V  +      E   +    H FQ + YLR +CNHP+L LT  HP ++T   +LA  N  L DI  + KL AL+QL+LDCG+G +G+  E   E SVVA +R+L+FCQ   M+++V+  +++  +P  T+LRLDGS+P   R  IV +F+ D SID+LLLTT +GGLGLNLT A+ V+FVEHDWNPMRDLQAMDRAHRIGQK  V VYRLIT  ++EEKIM LQ+FK  +AN V+S++N+ + SM T+ +L++   + +   +    S +GK  +              KS+L  +S       ++D  ++YD EY+L++F+
Sbjct:   10 GIVPY---IVLLVVPV-LGRMSDQTDSVRFMATQCFATLIRLMPLEAGIPDPPNMSAELIQLKAKERHFLEQLLDGKKLENYKIP-VPINAELRKYQQDGVNWLAFLNKYKLHGILCDDMGLGKTLQSICILAGDHCHRAQEYARSKLAECMPLPSLVVCPPTLTGHWVDEVGKF-CSREYLNPLHYTGPPTERIRLQHQVKRHNLIVASYDVVRNDIDFFRNIKF-------------------NYCILDEGHVIKNGKTKLSKAVKQLTANYRIILSGTPIQNNVLELWSLFDFLMPGFLGTERQFAARYGKPILASRDARSSSREQEAGVLAMDALHRQVLPFLLRRMKEDVLQDLPPKIIQDYYCTLSPLQVQLYEDFAKSRAKCDVD--ETVSSATLSEETEKPKLKATGHVFQALQYLRKLCNHPALVLTPQHPEFKTTAEKLAVQNSSLHDIQHAPKLSALKQLLLDCGLG-NGSTSESGTE-SVVAQHRILIFCQLKSMLDIVEHDLLKPHLPSVTYLRLDGSIPPGQRHSIVSRFNNDPSIDVLLLTTHVGGLGLNLTGADTVVFVEHDWNPMRDLQAMDRAHRIGQKRVVNVYRLITRGTLEEKIMGLQKFKMNIANTVISQENSSLQSMGTDQLLDLFTLDKDGKAEKADTSTSGKASM--------------KSILENLSD------LWD-QEQYDSEYSLENFM 676          

Query: 3410 GLLPYRLAIAVIILPVVLACLNAPFDPLRRVATHVFSXXXXXXXXESSGADLSILTPARQQQRKQHLSFLDSLLNPKLIGQYNAHHSVVSAKLRQYQEEGVNWLGFLNRYGLHGVLADDMGLGKTLQAICVIAGE-YSR--------APSTCP-PSLIVCPPTLTVHWHQEFKKFLVNLPDFNTIVYLGTPMYRQCIFNSLSRYQVVITSYDTLRSDMNLLARPTFPRCGTDVTKGSLMANSNVWNYVVLDEGHLIRNYKSKVAVATRALCARHRLVLTGTPIQNRVGELWSLFDFLMPGLLGTCTEFNRRYGRVLEQNGSNSGRKVDSEAGTLALELLHRQVLPFMLRRVKDDVLQELPPKIMQDYMCTMSPLQLRLYTHCMESQAATDT-DFVELVDKSYKENSAINQHRHGFQTMHYLRLVCNHPSLGLTSSHPLYRTLMRELAANNQCLDDINLSGKLVALRQLILDCGVGV-----SGAGEEELDETSVVASNRLLVFCQSIKMMELVDK-MIRNEIPKATHLRLDGSVPAKDRQQIVEKFSCDAXXXXXXXXXXXXXXXXXXXXANIVIFVEHDWNPMRDLQAMDRAHRIGQKHTVIVYRLITAQSIEEKIMNLQEFKKFLANAVVSKDNNQMASMNTENILEIMNKEANWPTQSPPASANGKQKVVSSVSGGTETQLGSKSVLSKISKADSGERVYDCLDEYDQEYNLDSFV 5515
             +LPY   I ++++PV L C+    +P+R +ATH F+ ++ LLPLE+   D   +      +R +   FL+ LL+      Y+    +  A+LR+YQ++GVNWLGFLN+Y LHG+L DDMGLGKTLQ+IC++A + Y R         P  CP PSL+VCPPTL  HW  E  KF+ N    N ++Y G P  R  +   + ++ +++ SYD +R+D+      TF                  WNY +LDEGH+IRN K+K++ A + L   HRL+L+GTPIQN V +LWSLFDFLMPG LGT  +F  RYG+ + Q+        + EAG LA+E LHRQVLPF+LRR+K+DVLQ+LPPKI+QDY C +SPLQ+ LY    +SQ   D  D V   D S K++       H FQ + YLR VCNHPSL LT+SHP Y  +M  L  +   + DI  + KL AL+QL+ DCG+GV     SG       +  VV  +R+L+FCQ   M+ +V++ +I+ E+P  T+LRLDG VPA  R  IV++F+ D SID+LLLTT +GGLGLNLT A+ VIFVEHDWNPM+DLQAMDRAHRIGQK  V VYRL+T  ++EEKIM LQ+FK  +AN V+S+DN+ + SM T+ +L +   +             G+  V S+ S     +   K++L      +S E ++D   +YD EY+L++F+
Sbjct:  291 NILPY---IVLLVVPV-LGCMCDQNEPVRLMATHCFAQMIRLLPLEAGIPDPPEMKGDLANRRDKERKFLEQLLDGSKSEDYDITVDI-KAELRKYQQDGVNWLGFLNKYKLHGILCDDMGLGKTLQSICILATDHYERQKQYQKENTPDCCPLPSLVVCPPTLVGHWVYEINKFVDN-DLLNPLMYAGPPSERIRLQKKVKKHNLIVASYDVVRNDIEFFT--TFR-----------------WNYCILDEGHIIRNGKTKLSKAVKQLLCNHRLILSGTPIQNNVLDLWSLFDFLMPGFLGTEKQFQARYGKPILQSRDGKSTTKEQEAGALAMEALHRQVLPFILRRLKEDVLQDLPPKIIQDYYCDLSPLQVELYEDFAKSQVKNDIEDDVVSEDSSGKKSQG---STHVFQALQYLRKVCNHPSLVLTTSHPKYDMIMSRLKHDKSSIHDIQHAPKLTALKQLLNDCGIGVGSSNTSGTSNILGTDVPVVNQHRVLLFCQLKSMLNIVEQDLIKREMPSVTYLRLDGGVPATSRHDIVQRFNNDPSIDMLLLTTHVGGLGLNLTGADTVIFVEHDWNPMKDLQAMDRAHRIGQKKVVNVYRLVTRGTLEEKIMGLQKFKLNIANTVISQDNSNLQSMATDQLLHLFTLD---------DMKKGESSVPSTSSDKPVKKESMKTIL------ESLEGLWD-EPQYDTEYDLNNFM 965          

Query: 3374 GAIELIYLVCHS---GLLPYRLAIAVIILPVVLACLNAPFDPLRRVATHVFSXXXXXXXXESSGADLSILTP--ARQQQRKQHLSFLDSLLNPKLIGQYNAHHSVVSAKLRQYQEEGVNWLGFLNRYGLHGVLADDMGLGKTLQAICVIAGEY---------SRAPSTCP-PSLIVCPPTLTVHWHQEFKKFLVNLPDFNTIVYLGTPMYRQCIFNSLSRYQVVITSYDTLRSDMNLLARPTFPRCGTDVTKGSLMANSNVWNYVVLDEGHLIRNYKSKVAVATRALCARHRLVLTGTPIQNRVGELWSLFDFLMPGLLGTCTEFNRRYGRVLEQNGSNSGRKVDSEAGTLALELLHRQVLPFMLRRVKDDVLQELPPKIMQDYMCTMSPLQLRLYTHCMESQAATDTDFV--ELVDKSYKENSAINQHRHGFQTMHYLRLVCNHPSLGLTSSHPLYRTLMRELAANNQCLDDINLSGKLVALRQLILDCGVGVSGAGEEELDETSVVASNRLLVFCQSIKMMELVDK-MIRNEIPKATHLRLDGSVPAKDRQQIVEKFSCDAXXXXXXXXXXXXXXXXXXXXANIVIFVEHDWNPMRDLQAMDRAHRIGQKHTVIVYRLITAQSIEEKIMNLQEFKKFLANAVVSKDNNQMASMNTENILEIMN-KEANWPTQSPPASANGKQKVVSSVSGGTETQLGSKSVLSKISKADSGERVYDCLDEYDQEYNLDSFV 5515
            GAIE +  V       ++PY   I ++++PV L  ++ P D +R +AT  F+ L+ LLPLE+   D   ++    RQ+ R++H  FL+ LL+ + +  Y     +  A+LR+YQ++GVNWL FLN+Y LHG+L DDMGLGKTLQ+IC++AG++         ++A  +CP PS++VCPPTLT HW  E  KF       N + Y G P  R  + + + ++ +V+ SYD +R+D++      F                   NY +LDEGH+I+N K+K++ A + L A +R++L+GTPIQN V ELWSLFDFLMPG LGT  +F  RYG+ +  +        + EAG LA+E LHRQVLPF+LRR+K+DVLQ+LPPKI+QDY C +SPLQ++LY    +S+A    D V    V +  +E   +    H FQ + YLR +CNHP+L LT  HP ++ +  +L++ +  L DI  + KL AL+QL+LDCG+G   AG  +    +VVA +R+L+FCQ   M+++V++ +++ ++P  T+LRLDGSVPA  R  IV +F+ D SID+LLLTT +GGLGLNLT A+ V+FVEHDWNPMRDLQAMDRAHRIGQK  V VYRLIT  ++EEKIM LQ+FK  +AN V+S+DN+ + SM T+ +L +    + +   +S  AS++GK  + S + G     LG                ++D   +Y+ EY+LDSF+
Sbjct: 1170 GAIEAMACVMEQLDVDIVPY---IVLLVVPV-LGRMSDPSDSVRFMATQCFATLIRLLPLEAGIPDPPSMSDDLIRQKARERH--FLEQLLDGRKLENYKIPVPI-KAELRKYQQDGVNWLAFLNKYKLHGILCDDMGLGKTLQSICILAGDHYLRAQEYTKTKAADSCPLPSIVVCPPTLTGHWVDEVGKFCTK-EYLNPLHYTGPPTERARLQHQVKKHNLVVASYDVVRNDIDFFRNIKF-------------------NYCILDEGHVIKNGKTKLSKAIKQLAANYRVILSGTPIQNNVLELWSLFDFLMPGFLGTERQFAARYGKPILASRDAKSSSREQEAGVLAMEALHRQVLPFLLRRMKEDVLQDLPPKIIQDYYCNLSPLQVQLYEDFAKSRAKVSVDDVISTAVKEEEEEKPKLKATGHVFQALQYLRKLCNHPALVLTPQHPEHKRISEQLSSQHSSLRDIQHAPKLSALKQLLLDCGLG--SAGSSDGGTEAVVAQHRVLIFCQLKSMLDIVEQDLLKPQLPSVTYLRLDGSVPAGLRHSIVSRFNNDPSIDVLLLTTHVGGLGLNLTGADTVVFVEHDWNPMRDLQAMDRAHRIGQKRVVNVYRLITRGTLEEKIMGLQKFKMSIANTVISQDNSSLQSMGTDQLLNLFTLDKDDKAEKSEVASSSGKASMKSVLDG-----LGD---------------LWD-QQQYEAEYDLDSFM 1852          

Query:  593 SMENSPKKPVKRPHEEVQDVNEPGTKMKC-VEKI-GNETERERNTEWPWVDFCEELLKNLWDAKWEIRHGAATCLRELIRSQGSIMLPKNANI--SSTDKFAACHERFQEEIVVRLLCTLTLDQLSDFVSDEMVAPVRESCAQALGVISVHLTRRLVEILANQLLSLLNHDEWRVNHXXXXXXXXXXXXRMDLVEVLLPIIYDPISSHLKGNXXXXXXXXXXXXLMPLFGDCCSNTVAISNEELDTLKTDLWDVLAVRIDCTTSGATCAVLQLLERLYEKCNVVYNQSEDQPMATDRVKALNEYINRLHWCYFNYS-DLVRLAAVRTCRAVLQSIGIKVGTILEHGTIXXXXXXXXXXXXIDDNCQVAAEAHSVWNQFIDSLPEQLLARVSCERLEIWMCSAMQPARLSYTPGSILMPDYIIXXXXXXXXXXXXDGLDEDDGNKHHILTEFYIGGRESFITDGSSAARDDLVXXXXXXXXXXXXXXXXXFIFHEAGIRNILI---SIIAQI---HLKDRLAVQRFVASMILAYWDPDHLLAMRNLNDCSL--SPLQSQLLTALEEPIYYQEILSQFKQMHKACRDLILIYIEREIPLPPSIMNAVGPNASPVSIALNISQCQSLISSEMCSLCPPESMTTFSCATAAVDTCAQQHATL 2527
            S E  P++  ++    V  +++P T+ K  ++ +  N +  E   EWP   FCEEL  +L++  WEIRHGA T LRE+++  G+        +  S++++ A  H+ + E++V+RLLC   LD+  DFVSDE+VAPVRE+CAQ LGV   H+T   V +  + LL LL  D+W V HG LLG+KY LA R +L+  LLP +   I+  L+ + DDDVR  A AAL+P+        V +   ++  +   LWD L    D T S  T +++ LL  L     + Y Q     M     ++L   + R+ W +  ++   VR AA+ T   +L S   + G +  +  +  +L  + Q  +++ N ++      VW + +   P+Q +   SC  +  W+C  MQ + +          D  +     A +     G     G +     + YIGG ++   D     RD +V RARL A +LL  LC+     +       I     +AQ+   HL  + A+QR   +M+L  W           N+C +  S +Q +LL  L E +YY EI   F +M   C+ LI +  +  I +   I ++V            I Q   L++            T FS ATA+++  ++Q   L
Sbjct:  245 SFEGEPEEKRRKTTNVV--IDQPATENKVLIDNVPDNSSLLEETQEWPLESFCEELCNDLFNPSWEIRHGAGTGLREVLKCHGT----GGGKLVGSTSEQLAQQHQEWMEDLVIRLLCVFALDRFGDFVSDEVVAPVRETCAQTLGVALRHMTDSGVAMTVDVLLKLLTEDQWEVRHGGLLGIKYALAVRQNLISELLPRVLPAITEGLQ-DLDDDVRAVAAAALIPVV----DGLVHLQPAKVPFIVNTLWDALLELDDLTAS--TNSIMTLLSSL-----LTYPQVLQCSMQ----QSLTVLVPRV-WPFLRHTIASVRRAALETLFTLL-SKADQSGAVWLNPILQDMLRHIFQSCILESNQEILDLIQKVWGELLRQAPQQYVVAASCPWMGAWICLMMQASHIPI--------DLNMLLEVKARSKEKASGKPRQGGTQVKEAVQEYIGGADTITED--QGTRDYVVTRARLMAAKLLGALCRCICDPQLNSSTQEIRPAESLAQLLLFHLNSKSALQRIAVAMVLCEWAFVQ-------NECEIVSSVVQPRLLAILSEQLYYDEIAIPFTRMQNECKQLISLLADAHIDVRERINSSV----------FTIDQANELVT------------TIFSDATASLNLKSRQFQPL 839          

Query: 3374 GAIELIYLVCHS---GLLPYRLAIAVIILPVVLACLNAPFDPLRRVATHVFSXXXXXXXXESSGADLSILTP--ARQQQRKQHLSFLDSLLNPKLIGQYNAHHSVVSAKLRQYQEEGVNWLGFLNRYGLHGVLADDMGLGKTLQAICVIAGEY---------SRAPSTCP-PSLIVCPPTLTVHWHQEFKKFLVNLPDFNTIVYLGTPMYRQCIFNSLSRYQVVITSYDTLRSDMNLLARPTFPRCGTDVTKGSLMANSNVWNYVVLDEGHLIRNYKSKVAVATRALCARHRLVLTGTPIQNRVGELWSLFDFLMPGLLGTCTEFNRRYGRVLEQNGSNSGRKVDSEAGTLALELLHRQVLPFMLRRVKDDVLQELPPKIMQDYMCTMSPLQLRLYTHCMESQAATDTDFV--ELVDKSYKENSAINQHRHGFQTMHYLRLVCNHPSLGLTSSHPLYRTLMRELAANNQCLDDINLSGKLVALRQLILDCGVGVSGAGEEELDETSVVASNRLLVFCQSIKMMELVDK-MIRNEIPKATHLRLDGSVPAKDRQQIVEKFSCDAXXXXXXXXXXXXXXXXXXXXANIVIFVEHDWNPMRDLQAMDRAHRIGQKHTVIVYRLITAQSIEEKIMNLQEFKKFLANAVVSKDNNQMASMNTENILEIMN 5314
            GAIE +  V       ++PY   I ++++PV L  ++ P D +R +AT  F+ L+ LLPLE+   D   ++    RQ+ R++H  FL+ LL+ + +  Y     +  A+LR+YQ++GVNWL FLN+Y LHG+L DDMGLGKTLQ+IC++AG++         ++A  +CP PS++VCPPTLT HW  E  KF       N + Y G P  R  + + + ++ +V+ SYD +R+D++      F                   NY +LDEGH+I+N K+K++ A + L A +R++L+GTPIQN V ELWSLFDFLMPG LGT  +F  RYG+ +  +        + EAG LA+E LHRQVLPF+LRR+K+DVLQ+LPPKI+QDY C +SPLQ++LY    +S+A    D V    V +  +E   +    H FQ + YLR +CNHP+L LT  HP ++ +  +L++ +  L DI  + KL AL+QL+LDCG+G   AG  +    +VVA +R+L+FCQ   M+++V++ +++ ++P  T+LRLDGSVPA  R  IV +F+ D SID+LLLTT +GGLGLNLT A+ V+FVEHDWNPMRDLQAMDRAHRIGQK  V VYRLIT  ++EEKIM LQ+FK  +AN V+S+DN+ + SM T+ +L +  
Sbjct: 1120 GAIEAMACVMEQLDVDIVPY---IVLLVVPV-LGRMSDPSDSVRFMATQCFATLIRLLPLEAGIPDPPSMSDDLIRQKARERH--FLEQLLDGRKLENYKIPVPI-KAELRKYQQDGVNWLAFLNKYKLHGILCDDMGLGKTLQSICILAGDHYLRAQEYTKTKAADSCPLPSIVVCPPTLTGHWVDEVGKFCTK-EYLNPLHYTGPPTERARLQHQVKKHNLVVASYDVVRNDIDFFRNIKF-------------------NYCILDEGHVIKNGKTKLSKAIKQLAANYRVILSGTPIQNNVLELWSLFDFLMPGFLGTERQFAARYGKPILASRDAKSSSREQEAGVLAMEALHRQVLPFLLRRMKEDVLQDLPPKIIQDYYCNLSPLQVQLYEDFAKSRAKVSVDDVISTAVKEEEEEKPKLKATGHVFQALQYLRKLCNHPALVLTPQHPEHKRISEQLSSQHSSLRDIQHAPKLSALKQLLLDCGLG--SAGSSDGGTEAVVAQHRVLIFCQLKSMLDIVEQDLLKPQLPSVTYLRLDGSVPAGLRHSIVSRFNNDPSIDVLLLTTHVGGLGLNLTGADTVVFVEHDWNPMRDLQAMDRAHRIGQKRVVNVYRLITRGTLEEKIMGLQKFKMSIANTVISQDNSSLQSMGTDQLLNLFT 1755          

Query:  593 SMENSPKKPVKRPHEEVQDVNEPGTKMKC-VEKI-GNETERERNTEWPWVDFCEELLKNLWDAKWEIRHGAATCLRELIRSQGSIMLPKNANI--SSTDKFAACHERFQEEIVVRLLCTLTLDQLSDFVSDEMVAPVRESCAQALGVISVHLTRRLVEILANQLLSLLNHDEWRVNHXXXXXXXXXXXXRMDLVEVLLPIIYDPISSHLKGNXXXXXXXXXXXXLMPLFGDCCSNTVAISNEELDTLKTDLWDVLAVRIDCTTSGATCAVLQLLERL 1411
            S E  P++  ++    V  +++P T+ K  ++ +  N +  E   EWP   FCEEL  +L++  WEIRHGA T LRE+++  G+        +  S++++ A  H+ + E++V+RLLC   LD+  DFVSDE+VAPVRE+CAQ LGV   H+T   V +  + LL LL  D+W V HG LLG+KY LA R +L+  LLP +   I+  L+ + DDDVR  A AAL+P+        V +   ++  +   LWD L    D T S  T +++ LL  L
Sbjct:  245 SFEGEPEEKRRKTTNVV--IDQPATENKVLIDNVPDNSSLLEETQEWPLESFCEELCNDLFNPSWEIRHGAGTGLREVLKCHGT----GGGKLVGSTSEQLAQQHQEWMEDLVIRLLCVFALDRFGDFVSDEVVAPVRETCAQTLGVALRHMTDSGVAMTVDVLLKLLTEDQWEVRHGGLLGIKYALAVRQNLISELLPRVLPAITEGLQ-DLDDDVRAVAAAALIPVV----DGLVHLQPAKVPFIVNTLWDALLELDDLTAS--TNSIMTLLSSL 508          

Query: 3584 RQQQRKQHLSFLDSLLNPKLIGQYNAHHSVVSAKLRQYQEEGVNWLGFLNRYGLHGVLADDMGLGKTLQAICVIAGEY---------SRAPSTCP-PSLIVCPPTLTVHWHQEFKKFLVNLPDFNTIVYLGTPMYRQCIFNSLSRYQVVITSYDTLRSDMNLLARPTFPRCGTDVTKGSLMANSNVWNYVVLDEGHLIRNYKSKVAVATRALCARHRLVLTGTPIQNRVGELWSLFDFLMPGLLGTCTEFNRRYGRVLEQNGSNSGRKVDSEAGTLALELLHRQVLPFMLRRVKDDVLQELPPKIMQDYMCTMSPLQLRLYTHCMESQAATDTDFV--ELVDKSYKENSAINQHRHGFQTMHYLRLVCNHPSLGLTSSHPLYRTLMRELAANNQCLDDINLSGKLVALRQLILDCGVGVSGAGEEELDETSVVASNRLLVFCQSIKMMELVDK-MIRNEIPKATHLRLDGSVPAKDRQQIVEKFSCDAXXXXXXXXXXXXXXXXXXXXANIVIFVEHDWNPMRDLQAMDRAHRIGQKHTVIVYRLITAQSIEEKIMNLQEFKKFLANAVVSKDNNQMASMNTENILEIMN-KEANWPTQSPPASANGKQKVVSSVSGGTETQLGSKSVLSKISKADSGERVYDCLDEYDQEYNLDSFV 5515
            RQ+ R++H  FL+ LL+ + +  Y     +  A+LR+YQ++GVNWL FLN+Y LHG+L DDMGLGKTLQ+IC++AG++         ++A  +CP PS++VCPPTLT HW  E  KF       N + Y G P  R  + + + ++ +V+ SYD +R+D++      F                   NY +LDEGH+I+N K+K++ A + L A +R++L+GTPIQN V ELWSLFDFLMPG LGT  +F  RYG+ +  +        + EAG LA+E LHRQVLPF+LRR+K+DVLQ+LPPKI+QDY C +SPLQ++LY    +S+A    D V    V +  +E   +    H FQ + YLR +CNHP+L LT  HP ++ +  +L++ +  L DI  + KL AL+QL+LDCG+G   AG  +    +VVA +R+L+FCQ   M+++V++ +++ ++P  T+LRLDGSVPA  R  IV +F+ D SID+LLLTT +GGLGLNLT A+ V+FVEHDWNPMRDLQAMDRAHRIGQK  V VYRLIT  ++EEKIM LQ+FK  +AN V+S+DN+ + SM T+ +L +    + +   +S  AS++GK  + S + G     LG                ++D   +Y+ EY+LDSF+
Sbjct: 1138 RQKARERH--FLEQLLDGRKLENYKIPVPI-KAELRKYQQDGVNWLAFLNKYKLHGILCDDMGLGKTLQSICILAGDHYLRAQEYTKTKAADSCPLPSIVVCPPTLTGHWVDEVGKFCTK-EYLNPLHYTGPPTERARLQHQVKKHNLVVASYDVVRNDIDFFRNIKF-------------------NYCILDEGHVIKNGKTKLSKAIKQLAANYRVILSGTPIQNNVLELWSLFDFLMPGFLGTERQFAARYGKPILASRDAKSSSREQEAGVLAMEALHRQVLPFLLRRMKEDVLQDLPPKIIQDYYCNLSPLQVQLYEDFAKSRAKVSVDDVISTAVKEEEEEKPKLKATGHVFQALQYLRKLCNHPALVLTPQHPEHKRISEQLSSQHSSLRDIQHAPKLSALKQLLLDCGLG--SAGSSDGGTEAVVAQHRVLIFCQLKSMLDIVEQDLLKPQLPSVTYLRLDGSVPAGLRHSIVSRFNNDPSIDVLLLTTHVGGLGLNLTGADTVVFVEHDWNPMRDLQAMDRAHRIGQKRVVNVYRLITRGTLEEKIMGLQKFKMSIANTVISQDNSSLQSMGTDQLLNLFTLDKDDKAEKSEVASSSGKASMKSVLDG-----LGD---------------LWD-QQQYEAEYDLDSFM 1749          

Query:  191 ISALLAKLLPYAKHKIWVVRIAASDAVRHIGNNAKLW--VPGTSESNVTNVSNLINLE-------NLNLHDILKIGTRLYSRDFKDLD---EANTNQNINRDELARHLGFLI-----PDECEIKNLITVKDCELVESKSENKMSVELAVMKSMENSPKKPVKRPHEEVQDVNEPGTKMKCVEKIGNETERERNTEWPWVDFCE----ELLKNLWDAKWEIRHGAATCLRELIRSQGSIMLPKNANI--SSTDKFAACHERFQEEIVVRLLCTLTLDQLSDFVSDEMVAPVRESCAQALGVISVHLTRRLVEILANQLLSLLNHDEWRVNHXXXXXXXXXXXXRMDLVEVLLPIIYDPISSHLKGNXXXXXXXXXXXXLMPLFGDCCSNTVAISNEELDTLKTDLWDVLAVRIDCTTSGATCAVLQLLERLYEKCNVVYNQSEDQPMATDRVKALNEYINRLHWCYFNYS-DLVRLAAVRTCRAVLQSIGIKVGTILEHGTIXXXXXXXXXXXXIDDNCQVAAEAHSVWNQFIDSLPEQLLARVSCERLEIWMCSAMQPARLSYTPGSILMPDYIIXXXXXXXXXXXXDGLDEDDGNKHHILTEFYIGGRESFITDGSSAARDDLVXXXXXXXXXXXXXXXXXFIFHEAGIRNILI---SIIAQI---HLKDRLAVQRFVASMILAYWDPDHLLAMRNLNDCSL--SPLQSQLLTALEEPIYYQEILSQFKQMHKACRDLILIYIEREIPLPPSIMNAVGPNASPVSIALNISQCQSLISSEMCSLCPPESMTTFSCATAAVDTCAQQHATL 2527
            ++ LLAK+L Y +   W  RIAA  AV  I  N   W   P   E  V     L            L++   + + T     D +DLD    +N N+         H   LI     P     +     +  +LV  +    +        S E  P++  ++    V  +++P T+ K +  I N  +     E    + CE    E    +     +IRHGA T LRE+++  G+        +  S++++ A  H+ + E++V+RLLC   LD+  DFVSDE+VAPVRE+CAQ LGV   H+T   V +  + LL LL  D+W V HG LLG+KY LA R +L+  LLP +   I+  L+ + DDDVR  A AAL+P+        V +   ++  +   LWD L    D T S  T +++ LL  L     + Y Q     M     ++L   + R+ W +  ++   VR AA+ T   +L S   + G +  +  +  +L  + Q  +++ N ++      VW + +   P+Q +   SC  +  W+C  MQ + +          D  +     A +     G     G +     + YIGG ++   D     RD +V RARL A +LL  LC+     +       I     +AQ+   HL  + A+QR   +M+L  W           N+C +  S +Q +LL  L E +YY EI   F +M   C+ LI +  +  I +   I ++V            I Q   L++            T FS ATA+++  ++Q   L
Sbjct:   40 LNNLLAKVLLYLRSPNWDTRIAAGQAVEAIVKNIPEWNPSPKPKEGEVDPKERLARQRKLLQKKLGLDMGAAIGMDTEELFND-EDLDYTCASNANRCKQPTSSLWHAAELIDSEFRPGMSNRQRNKAKRMAKLVAKQRSRDLDPNEKSNDSFEGEPEEKRRKTTNVV--IDQPATENKVL--IDNVPDNSSLLE----EVCEHNMSEFKTRVCIFGLQIRHGAGTGLREVLKCHGT----GGGKLVGSTSEQLAQQHQEWMEDLVIRLLCVFALDRFGDFVSDEVVAPVRETCAQTLGVALRHMTDSGVAMTVDVLLKLLTEDQWEVRHGGLLGIKYALAVRQNLISELLPRVLPAITEGLQ-DLDDDVRAVAAAALIPVV----DGLVHLQPAKVPFIVNTLWDALLELDDLTAS--TNSIMTLLSSL-----LTYPQVLQCSMQ----QSLTVLVPRV-WPFLRHTIASVRRAALETLFTLL-SKADQSGAVWLNPILQDMLRHIFQSCILESNQEILDLIQKVWGELLRQAPQQYVVAASCPWMGAWICLMMQASHIPI--------DLNMLLEVKARSKEKASGKPRQGGTQVKEAVQEYIGGADTITED--QGTRDYVVTRARLMAAKLLGALCRCICDPQLNSSTQEIRPAESLAQLLLFHLNSKSALQRIAVAMVLCEWAFVQ-------NECEIVSSVVQPRLLAILSEQLYYDEIAIPFTRMQNECKQLISLLADAHIDVRERINSSV----------FTIDQANELVT------------TIFSDATASLNLKSRQFQPL 780          

Query: 3683 KLRQYQEEGVNWLGFLNRYGLHGVLADDMGLGKTLQAICVIAG-EYSRAPSTCP--------PSLIVCPPTLTVHWHQEFKKFLVNLPDFNTIVYLGTPMY----RQCIFNSLSRYQVVITSYDTLRSDMNLLARPTFPRCGTDVTKGSLMANSNVWNYVVLDEGHLIRNYKSKVAVATRALCARHRLVLTGTPIQNRVGELWSLFDFLMPGLLGTCTEFNRRYGRVLEQNGSNSGRKVDSEAGTLALELLHRQVLPFMLRRVKDDVLQE--LPPKIMQDYMCTMSPLQLRLYTHCMESQAATDTDFVELVDKSYKENSAINQHRHGFQTMHYLRLVCNHPSLGLTSSHPLYRTLMRELAANNQCLDDINLSGKLVALRQLILDCGVGVSGAGEEELDETSVVASNRLLVFCQSIKMMELVDKMIRNEIPKATHLRLDGSVPAKDRQQIVEKFSCDAXXXXXXXXXXXXXXXXXXXXANIVIFVEHDWNPMRDLQAMDRAHRIGQKHTVIVYRLITAQSIEEKIMNLQEFKKFLANAVVSKDNNQMASMNTENILEIMNKEANWPTQSPPASANGKQKVVSSVSGGTETQL 5410
            KL +YQ+ GV W+  L+     G+L D+MGLGKT+Q I  +AG  YS+  +           P++IVCP T+   W +EF  +    P F   V   T  +     + I    + + ++ITSY  +R   + + +                     W+YV+LDEGH IRN  + V VA +     HR +L+G+P+QN + ELWSLFDF+ PG LGT   F  ++   +   G ++   V  +       +L   + P++LRR+K DV     LP K  Q   C ++  Q ++Y   ++S+                    +N     F  +  LR +CNHP L  +    L + +  E  +  +       SGKL+ +  L+                       +R+L+F QS +M+E+++  +R      + L++DG+     RQ ++ +++ D  I + LLTT +GGLG+NLT AN VI  + DWNP  D QA +RA RIGQK  V VYRL+TA +IEEKI + Q FK+FL N V+ KD  Q     + +I E+        T S P  + G +        G++ Q+
Sbjct:  484 KLFKYQQTGVRWMWELHCQQAGGILGDEMGLGKTIQVIAFLAGLSYSKLRTRGSNYRYAGLGPTVIVCPATVMHQWVKEFHTWW---PPFRVAVLHETGSFTSKREKLIPEIAAGHGILITSYSYVRIMQDYIQKYD-------------------WHYVILDEGHKIRNPNAGVTVACKQFRTPHRFILSGSPMQNNLKELWSLFDFVFPGKLGTLPVFMEQFSVPITMGGYSNASPVQVQTAYKCACVLRDSINPYLLRRMKADVKANLALPDKSEQVLFCRLTEDQRKVYQDFLDSKEVYQI---------------LNGDMQVFSGLIALRKICNHPDL-FSGGPRLLKGVPEEELSEEEHFGYWKRSGKLIVVESLL----------------RLWYKQGHRVLLFTQSRQMLEILEVFVRGN--GYSFLKMDGTTTIASRQPLIARYNED--IFVFLLTTKVGGLGVNLTGANRVIIYDPDWNPSTDTQARERAWRIGQKQQVTVYRLLTAGTIEEKIYHRQIFKQFLTNRVL-KDPKQRRFFKSNDIYELF-------TLSSPDGSQGTETSAIFAGTGSDVQI 1008          

Query: 3671 VVSAKLRQYQEEGVNWLGFLNRYGLHGVLADDMGLGKTLQAICVIA--GEYSRAPSTCPPSLIVCPPTLTVHWHQEFKKFLVNLPDFNTIVYLGTPMYRQCIFNSL--SRYQVVITSYDTLRSDMNLLARPTFPRCGTDVTKGSLMANSNVWNYVVLDEGHLIRNYKSKVA-VATRALCARHRLVLTGTPIQNRVGELWSLFDFLMPGLLGTCTEFNRRYGRVLEQNGSNSGRKVD--SEAGTLALELLHRQVLPFMLRRVKDDVLQELPPKIMQDYMCTMSPLQLRLYTHCMESQAATDTDFVELVDKSYKENSAINQHRHGFQTMHYLRLVCNHPSLGLTSSHPLYRTLMRELAANN---QCLDDINLSGKLVALRQLILDCGVGVSGAGEEELDETSVVASN-RLLVFCQSIKMMELVDKMI--RNEIPKATHLRLDGSVPAKDRQQIVEKFS-CDAXXXXXXXXXXXXXXXXXXXXANIVIFVEHDWNPMRDLQAMDRAHRIGQKHTVIVYRLITAQSIEEKIMNLQEFKKFLANAVV 5254
            +++ +L+QYQ +G+ WL  L    L+G+LAD+MGLGKT+Q I +I    EY R      P LI+ P +   +W  EF K+    P    + Y G+P  R+     L   ++ V++T+Y+ +  D  +LA+                     W Y+++DEGH ++N+  K+  V      A  R++LTGTP+QN++ ELW+L +FL+P +  +C+ F + +        + +G KVD   E   L +  LH+ + PF+LRR+K +V  +LP K+     C MS LQ  LY H M+++    TD  E   K       +        T+  LR +CNHP +       +  +    L  +    Q  D    SGK   L +++                   + A+N ++L+FCQ   +M +++     RN      +LRLDG+  A+DR  +++ F+  ++   I LL+T  GGLGLNL SA+ V+  + DWNP +DLQA DRAHRIGQ++ V V RL T  S+EEKI+   ++K  +   V+
Sbjct:  686 LINGQLKQYQIKGLEWLVSLYNNNLNGILADEMGLGKTIQTIALITYLMEYKRLNG---PYLIIVPLSTLSNWVYEFDKWA---PSVVKVSYKGSPAARRAFVPQLRSGKFNVLLTTYEYIIKDKQVLAKIR-------------------WKYMIVDEGHRMKNHHCKLTQVLNTHYLAPRRVLLTGTPLQNKLPELWALLNFLLPTIFKSCSTFEQWFNAPF----AMTGEKVDLNEEETILIIRRLHKVLRPFLLRRLKKEVEAQLPEKVEYVIKCDMSALQRVLYRH-MQAKGVLLTDGSEKDKKGKGGTKTL------MNTIMQLRKICNHPYM----FQQIEESFSEHLGFSGGIVQGADLYRASGKFEVLDRIL-----------------PKLRATNHKVLLFCQMTTLMTIMEDYFAYRN----FKYLRLDGTTKAEDRGMLLKTFNDPESQYFIFLLSTRAGGLGLNLQSADTVVIFDSDWNPHQDLQAQDRAHRIGQQNEVRVLRLCTVNSVEEKILAAAKYKLNVDQKVI 1166          

Query: 3374 GAIELIYLVCHS---GLLPYRLAIAVIILPVVLACLNAPFDPLRRVATHVFSXXXXXXXXESSGADLSILTPARQQQRKQHLSFLDSLLNPKLIGQYNAHHSVVSAKLRQYQEEGVNWLGFLNRYGLHGVLADDMGLGKTLQAICVIAG-------EYSR---APSTCPPSLIVCPPTLTVHWHQEFKKFLVNLPDF-NTIVYLGTPMYRQCIFNSLSRYQVVITSYDTLRSDMNLLARPTFPRCGTDVTKGSLMANSNV-WNYVVLDEGHLIRNYKSKVAVATRALCARHRLVLTGTPIQNRVGELWSLFDFLMPGLLGTCTEFNRRYGRVLEQNGSNSGRKVDSEAGTLALELLHRQVLPFMLRRVKDDVLQELPPKIMQDYMCTMSPLQLRLYTHCMESQAATDTDFVELVDKSYKENSAINQHR---HGFQTMHYLRLVCNHPSLGLTSSHPLYRTLMRELAANNQCLDDINLSGKLVALRQLILDCGVGVSGAGEE-ELDETSVVASNRLLVFCQSIKMMELVDK-MIRNEIPKATHLRLDGSVPAKDRQQIVEKFSCDAXXXXXXXXXXXXXXXXXXXXANIVIFVEHDWNPMRDLQAMDRAHRIGQKHTVIVYRLITAQSIEEKIMNLQEFKKFLANAVVSKDNNQMASMNTENILEIMNKEANWPTQSPPASANGKQKVVSSVSGGTETQLGSKSVLSKISKADSGERVYDCLDEYDQEYNLDSFV 5515
            GAIE +  V  +    ++PY   + ++++PV +  ++     +R +AT  F+ L+ L+PLE+   D   ++     Q+ +   FL+ LL+   +  Y A    + A+LR+YQ++GVNWL FLN+Y LHG+L DDMGLGKTLQ+IC++AG       EY R   A     PS++VCPPTLT HW  E  KF     +F N + Y G P  R  +   +  + +V+ SYD +R+D++                       N+ WNY +LDEGH+I+N K+K++ A + L A HRL+L+GTPIQN V ELWSLFDFLMPG LGT  +F  RYG+ +  +        + EAG LA+E LHRQVLPF+LRR+K+DVLQ+LPPKI+QDY C++SPLQ+RLY     SQA  D D      K   E S   + +   H FQ + YLR +CNHP+L LT  HP ++ +  ELA +   L DI  + KL AL+QL+LDCG+G  G     +    +VVA +R+L+FCQ   M+++V+  ++R ++P  T+LRLDGSVPA  R  IV +F+ D SID+LLLTT +GGLGLNLT A+ V+FVEHDWNPMRDLQAMDRAHRIGQK  V VYRLIT  ++EEKIM LQ+FK  +AN V+++DN  + SM TE +L++   E             G     +  SGG   +   KSVL  +        ++D  ++YD EYNLDSF+
Sbjct: 1156 GAIEALACVMDALDVDIVPY---MVLLVVPV-MGRMSDQTGSVRLMATQCFATLIRLMPLEAGIPDPPFMSQELASQKVRERHFLEQLLDGSKLDNY-AIPVPIHAELRKYQQDGVNWLSFLNKYKLHGILCDDMGLGKTLQSICILAGDHYLRAQEYERTQAADCATLPSMVVCPPTLTGHWVDEVHKFCPR--EFLNPLHYTGPPSERIRLQRYIKNHNLVVASYDVVRNDIDFF--------------------KNIKWNYCILDEGHMIKNGKTKLSKAVKQLTANHRLILSGTPIQNNVLELWSLFDFLMPGFLGTEHQFAARYGKPILASRDARSSSREQEAGVLAMEALHRQVLPFLLRRMKEDVLQDLPPKIIQDYYCSLSPLQVRLYEDFARSQAKHDLDDTISSGKLSSEPSDKTKLKATGHVFQALQYLRKLCNHPALVLTLQHPEFQRICEELATHGSSLRDIQHAPKLSALKQLLLDCGLGGGGGAGGVDSGPEAVVAQHRVLIFCQLKSMLDMVENDLLRPQLPAVTYLRLDGSVPAGQRHSIVARFNNDPSIDVLLLTTHVGGLGLNLTGADTVVFVEHDWNPMRDLQAMDRAHRIGQKRVVNVYRLITRGTLEEKIMGLQKFKLSIANTVINQDNASLQSMGTEQLLDLFTLE-----------KQGGLSEDAPSSGGASKKETIKSVLENLGD------LWD-QEQYDSEYNLDSFI 1844          

Query:   89 RLDKLFELLESNHQNI-RNAAAIQIGQLSANNQVNISALLAKLLPYAKHKIWVVRIAASDAVRHIGNNAKLWVP---------GTSESNVTNVSNLINLENLNLHDILKIGTRLYSRDFKDLD-EANTNQNINRDE--------LARHLGFLIPDECEIKNLITVKDCELVESKSENKMS----------VELAVMKSMENSPKKPVKR--------PHEEVQDV--------NEPGTKMKCV--------EKIGNETERERN------TEWPWVDFCEELLKNLWDAKWEIRHGAATCLRELIRSQG-SIMLPKNANISSTDKFAACHERFQEEIVVRLLCTLTLDQLSDFVSDEMVAPVRESCAQALGVISVHLTRRLVEILANQLLSLLNHDEWRVNHXXXXXXXXXXXXRMDLVEVLLPIIYDPISSHLKGNXXXXXXXXXXXXLMPLFGDCCSNTVAISNEELDTLKTDLWDVLAVRIDCTTSGATCAVLQLLERLYEKCNVVYNQSEDQPMATDRVKALNEYINRLHWCYFNY-SDLVRLAAVRTCRAVLQSIGIKVGTILEHGTIXXXXXXXXXXXXIDDNCQVAAEAHSVWNQFIDSLPEQLLARVSCERLEIWMCSAMQPARLSYTPGSILMPDYIIXXXXXXXXXXXXDGLDEDDGNKHHILTEFYIGGRESFITDGSSAARDDLVXXXXXXXXXXXXXXXXXFIFHEAGIRNILI---SIIAQI---HLKDRLAVQRFVASMILAYWDPDHLLAMRNLNDCSLSPLQSQLLTALEEPIYYQEILSQFKQMHKACRDLILIYIEREIPLPPSIMNAV 2368
            RLD+LF LL++    + R AAA Q+G++   +   +  LLAK++ Y +   W  RIAA  AV  I  N   W P            +S  +   + +     ++  +LK G  L      + D + + + N++  E        L + LG  +     +       D +L  S S    +          +E      M N  K   KR           E  DV         EP  K + V        +K+  ET  E +       EWP+  FCEEL  +L+   WE+RHGAAT LRE++++ G S   P +A +   ++    H+++ E++ +RLLC   LD+  DFVSDE+VAPVRE+CAQ LGV+  H+    V      LL LL  ++W V HG LLGLKY LA R DL+E LLP     +   L+   DD    AA A +         + V +  E++  +   LWD L    D T S  T +++ LL  L     V  N  +         ++    + R+ W +  + S  VR AA+ T   +L +   +  ++     +  ++  + Q  +++ +  +      VW + +   P Q +   +C  +  W+C  MQP+ +   P  ++            A       +    G     +   YI G E+   D +S  RD  V+R RL   +LL  L          + +  I     +AQ+   +L  + A+QR   S++++ W  DH      ++D     ++ +L   L E +YY EI   F +M   C+ L+ + +E    + P + +AV
Sbjct:    5 RLDRLFILLDTGTTPVTRKAAAQQLGEVQRLHPHELHNLLAKVITYLRSPNWDTRIAAGQAVEAIARNVPEWNPLPKSKLEGEQGRQSPDSQDDDRLAFRRFDIARLLKHGASLLGSTGAEFDVQDDKSGNVDPKERIARQRKLLQKKLGLDVGSALGMNTHELFDDDDLNASSSSTNHTKPQPFNAVEIMESEFAHGMSNRQKNKAKRMAKLHAKQRSRENADVATTSDTVDGEPDEKKRKVAVEVPIVEDKVLLETLPENSCLFEEMNEWPFESFCEELCNDLFSPSWEVRHGAATGLREVLKAHGPSGGKPADATLEEIEE---QHQQWLEDLAIRLLCVFALDRFGDFVSDEVVAPVRETCAQTLGVVLRHMRAEGVLGATRVLLQLLGQEQWEVRHGGLLGLKYTLAVRQDLIEALLPRTLPVVIEGLQDMDDDVRAVAAAALVP-----VVESLVQLHPEKIPVIMNTLWDSLLELDDLTAS--TNSIMTLLSSLLIYPAVRLNSMQ---------QSFTVLVPRV-WPFLRHNSSSVRKAALETLNTILSTQDSQSCSLWLTPILQDMMRFIYQVAILESSQDICYLVQKVWQELLAKAPLQYIVAAACPWMGAWLCLMMQPSHMPIDPNMLM---------ETRARAKDKCNVKARPGQPVREVRHEYIAGSETVHEDPTS--RDYHVMRTRLLNARLLGALSCCISHPSVNLASQEIRPAESLAQLLLFYLNSKSALQRIAVSLVISEW-ADHKQDCTTVSDA----VRPRLQAVLSEQLYYDEIAVPFTRMQTECKQLVSVLLEGGCDVRPRLASAV 795          

Query: 3671 VVSAKLRQYQEEGVNWLGFLNRYGLHGVLADDMGLGKTLQAICVIA--GEYSRAPSTCPPSLIVCPPTLTVHWHQEFKKFLVNLPDFNTIVYLGTPMYRQCIFNSL--SRYQVVITSYDTLRSDMNLLARPTFPRCGTDVTKGSLMANSNVWNYVVLDEGHLIRNYKSKVA-VATRALCARHRLVLTGTPIQNRVGELWSLFDFLMPGLLGTCTEFNRRYGRVLEQNGSNSGRKVD--SEAGTLALELLHRQVLPFMLRRVKDDVLQELPPKIMQDYMCTMSPLQLRLYTHCMESQAATDTDFVELVDKSYKENSAINQHRHGFQTMHYLRLVCNHPSLGLTSSHPLYRTLMRELAANN---QCLDDINLSGKLVALRQLILDCGVGVSGAGEEELDETSVVASNRLLVFCQSIKMMELVDKMIRNEIPKATHLRLDGSVPAKDRQQIVEKFS-CDAXXXXXXXXXXXXXXXXXXXXANIVIFVEHDWNPMRDLQAMDRAHRIGQKHTVIVYRLITAQSIEEKIMNLQEFKKFLANAVV 5254
            +V+  L+ YQ +G+ WL  L    L+G+LAD+MGLGKT+Q I +I    E+ R      P LI+ P +   +W  EF K+    P    I Y G+P+ R+     L   ++ V++T+Y+ +  D ++LA+                     W Y+++DEGH ++N+  K+  V      A  RL+LTGTP+QN++ ELW+L +FL+P +  +C+ F + +        + +G KVD   E   L +  LH+ + PF+LRR+K +V  +LP K+     C MS LQ  LY H M+++    TD  E   K       +        T+  LR + NHP +     H +  +    L   N   Q  D    SGK   L +++                    V+++R+L+FCQ   +M +++           +LRLDG+  ++DR  +++ F+  ++   I LL+T  GGLGLNL +A+ VI  + DWNP +DLQA DRAHRIGQ++ V V RL T  S+EEKI+   ++K  +   V+
Sbjct:  731 LVNGSLKMYQVQGLEWLVSLYNNNLNGILADEMGLGKTIQTIALITYLMEHKRLNG---PFLIIVPLSTLSNWMMEFDKWG---PSVVKISYKGSPIARRAFMPQLRSGKFNVLLTTYEYIIKDKHVLAK-------------------LRWKYMIVDEGHRMKNHHCKLTQVLNTHYIAPRRLLLTGTPLQNKLPELWALLNFLLPTIFKSCSTFEQWFNAPF----ALTGEKVDLNEEETILIIRRLHKVLRPFLLRRLKKEVESQLPEKVEYVIKCDMSALQKVLYRH-MQAKGVLLTDGSEKDKKGKGGAKTL------MNTIVQLRKIANHPYM---FQH-IEESFAEHLGFPNSIVQGADLFRASGKFELLDRILPKL----------------RVSNHRVLLFCQMTSLMTIMEDYF--AFRSFRYLRLDGTTKSEDRSNLLKTFNEPNSPYFIFLLSTRAGGLGLNLQAADTVIIFDSDWNPHQDLQAQDRAHRIGQQNEVRVLRLCTVNSVEEKILAAAKYKLNVDQKVI 1211          

Query: 3671 VVSAKLRQYQEEGVNWLGFLNRYGLHGVLADDMGLGKTLQAICVIAGEYSRAPSTCP-PSLIVCPPTLTVHWHQEFKKFLVNLPDFNTIVYLGTPMYR----QCIFNSLSRYQVVITSYDTLRSDMNLLARPTFPRCGTDVTKGSLMANSNVWNYVVLDEGHLIRNYKSKVAVATRALCARHRLVLTGTPIQNRVGELWSLFDFLMPGLLGTCTEFNRRYGRVLEQNGSNSGRKVDSEAGTLALELLHRQVLPFMLRRVKDDVLQELPPKIMQDYMCTMSPLQLRLYTHCMESQAATDTDFVELVDKSYKENSAINQHRHG-FQTMHYLRLVCNHPSL--GLTSSHPLYRTLMRELAANNQCLDDINLSGKLVALRQLILDCGVGVSGAGEEELDETSVVASNRLLVFCQSIKMMELVDK--MIRNEIPKATHLRLDGSVPAKDRQQIVEKFSC-DAXXXXXXXXXXXXXXXXXXXXANIVIFVEHDWNPMRDLQAMDRAHRIGQKHTVIVYRLITAQSIEEKIMNLQEFKKFLANAVVSK 5260
            V    +R YQ  G+NWL  L   G++G+LAD+MGLGKTLQ I ++   Y +     P P +++ P +   +W  EF++++   P    +  +G   +R    Q I   +  + V +TSY+ +                  + + S+    N W Y+V+DE H I+N KSK++   R     +RL+LTGTP+QN + ELWSL +FL+P +  +   F   +    + N     +++        +E LH  + PF+LRR+K DV + LPPK        +S +Q   YT  +      D D +         NSA    +      +  LR  CNHP L  G     P   T    +  N         SGK+V L +L+             +L E      +R+L+F Q  +MM++++   M R       + RLDG  P +DRQ  +  F+  D+S  + +L+T  GGLG+NL +A++VI  + DWNP  DLQAMDRAHRIGQK  V V+R IT  ++E++I+   E K  L + V+ +
Sbjct:  107 VKCGTMRDYQVRGLNWLISLYENGINGILADEMGLGKTLQTISLLG--YMKHYRNIPGPHMVLVPKSTLHNWMAEFERWV---PSLRAVCLIGDKDHRVSASQPIVPPIE-WDVCVTSYEMI------------------IREKSVFKKFN-WRYLVIDEAHRIKNEKSKLSEIVREFKTTNRLLLTGTPLQNNLHELWSLLNFLLPDVFNSADTFTSWF----DTNNCFGDQQL--------VERLHMVLRPFLLRRIKADVEKSLPPKKECKIYIGLSKMQREWYTKIL----MKDIDIL---------NSAGKMDKMRLLNILMQLRKCCNHPYLFDGAEPGPPY--TTDTHIVIN---------SGKMVVLDKLL------------PKLHE----QGSRVLIFSQMTRMMDILEDYCMWRG----YEYCRLDGQTPHEDRQVSIASFNAPDSSKFVFMLSTRAGGLGINLATADVVILYDSDWNPQVDLQAMDRAHRIGQKKVVRVFRFITESTVEDRIVERAEMKLRLDSIVIQQ 566          

Query: 3683 KLRQYQEEGVNWLGFLNRYGLHGVLADDMGLGKTLQAICVIAGEYSRAPSTCPPSLIVCPPTLTVHWHQEFKKFLVNLPDFNTIV------YLGTPMYRQC-IFNSLSRYQV---------VITSYDTLRSDMNLL-------ARPTFPRCGTDVTKGSLMA--NSNVWNYVVLDEGHLIRNYKSKVAVATRALCARHRLVLTGTPIQNRVGELWSLFDFLMPGLLGTCTEFNRRYGRVLEQNGSNSGRKVDSEAGTLALELLHRQVLPFMLRRVKDDVLQEL--PPKIMQDYMCTMSPLQLRLYTHCMESQAATDTDFVELVDKSYKENSAINQHRHGFQTMHYLRLVCNHPSLGLTSSHPLYRTLMRELAANNQCLDDINLSGKLVALRQLILDCGVGVSGAGEEELDETSVVASNRLLVFCQSIKMMELVDKMIRNEIPKATHLRLDGSVPAKDRQQIVEKFSCDAXXXXXXXXXXXXXXXXXXXXANIVIFVEHDWNPMRDLQAMDRAHRIGQKHTVIVYRLITAQSIEEKIMNLQEFKKFLANAVVSKDNNQMASMNTENILEIM 5311
            KL +YQ+ GV WL  L+     G+L D+MGLGKT+Q I  +AG   R      PSL+VCP T+   W +EF  +    P F   V      Y G    R+   F S S Y           V+ + D + + M+ +       A  T  RC    T+  ++A    + W        H  RN  +K+          HR++L+G+P+QN + ELWSLFDF+ PG LGT   F  ++   + Q G ++   V  +       +L   + PF+LRR+K DV   L  P K  Q        ++  L  +   SQ      + + +D S +    +N+ R  F  +  LR +CNHP L           L   L A +        SGKL+ +                E L        +R+L+F QS +M+++++K ++ E    +++++DG+     RQ +++KF+ D S+ + LLTT +GG+G+NLT AN VI  + DWNP  D QA +RA RIGQ   V +YRL++A +IEEKI + Q FK+FL N V+ KD  Q       ++ E+ 
Sbjct:   14 KLYKYQQTGVQWLWELHVKQAGGILGDEMGLGKTVQIIAFLAGLSHRYEG-LGPSLVVCPTTVMHQWVREFHTWW---PQFRVAVLHESGSYSGKKKVRRARFFYSYSTYSRAPLWKRPPPVLRASDGVAAIMHNMYIMFGGQASQTTFRC-LQFTRMLIIAIVFRSKWTCPRRAAHHPCRNADNKIFPNCFMFRTPHRIILSGSPVQNNLKELWSLFDFVFPGKLGTLPVFMEQFSVPITQGGYSNASDVQVQTAYKCACVLRDTIKPFLLRRMKADVKVNLALPDKNEQ--------VKALLKYNFQRSQV-----YQKFLD-SREVQQVLNRERQVFTALITLRKICNHPDL-----------LTGGLNAEDDGFGYWRRSGKLLVV----------------EALLRMWRRQGHRVLLFTQSRQMLDILEKFVQGE--GYSYMKMDGTTSIATRQPLIDKFNKDESMFMFLLTTHVGGIGVNLTGANRVIIFDPDWNPSTDTQARERAWRIGQLRQVTIYRLVSAGTIEEKIYHRQIFKQFLTNRVL-KDPRQQRFFKANDLFELF 534          

Query: 3653 YNAHHSVVSAKLRQYQEEGVNWLGFL---NRYGLHGVLADDMGLGKTLQAICVIAGEYSRAPSTCPPSLIVCPPTLTVHWHQEFKKFLVNLPDFNTIVYLGTPMYRQCIFNSLSRYQ-VVITSYDTLRSDMNLLARPTFPRCGTDVTKGSLMANSNVWNYVVLDEGHLIRNYKSKVAVATRALCARHRLVLTGTPIQNRVGELWSLFDFLMPG-LLGTCTEFNRRYGRVLEQNGSNSGRKVDSEAGTLAL-----ELLHRQVLPFMLRRVKDDVL-QELPPKIMQD-----------------YMCTMS---PLQLRLYTHCMESQAATD----TDFVELVDKSYKENSAINQHRHGFQTMHYLRLVCNHP---------SLGLTSSHPLYRTLMRELAANNQCLDDINLSGKLVALRQLILDCGVGVSGAGEEELDETSVVASNRLLVFCQSIKMMELVDKMIRNEIPKATHLRLDGSVP-AKDRQQIVEKFSCDAXXXXXXXXXXXXXXXXXXXXANIVIFVEHDWNPMRDLQAMDRAHRIGQKHTVIVYRLITAQSIEEKIMNLQEFKKFLANAVVSKDNNQMASMNTENILEIM 5311
            +N +H +   +L  +Q EGV WL  L    R G  G+LADDMGLGKT+Q I  ++G +    S     L+V P TL   W  EF K+    P      + GT   R      + R Q VVITSY  L ++ + L+              +      +W+ ++LDEGH I+   +K A +  A+ A  R++LTGTP+QN + E+W+LFDF+  G LLGT   F   Y     +N     R+ D+  G  AL     E L   + P+ LRR K +V  +EL  K ++D                  M T++    L + +Y   ++ Q   D     D  EL+D +          R     +  L+ +C HP          LGL +    +R +  E   +N  L  I    K V  + LI + G      G   L E      +R LVF QS+KM++++D +++++  K   +R+DG++    +R++ V+ F  D++ ++ LLTT +GG+GL LT+AN V+ ++  WNP  D QA+DRA+RIGQ   VI+YRL+T  ++EEKI   Q FK+ L         N     + + + E+ 
Sbjct:   88 FNLYHEL-HNQLYSHQLEGVAWLYNLFKNKRKG--GILADDMGLGKTIQVISFLSGMFD--ASLFGHVLLVMPTTLMSIWISEFDKWA---PGITIREFYGTKSERTRNLQKVQRTQGVVITSYQLLVNNWHELS--------------TYQGQEFIWDAMILDEGHKIKTSSTKTAKSAHAIPAHFRMILTGTPVQNNLKEIWALFDFVCEGSLLGTSKTFKMEY-----ENPITKARQKDATVGEKALGTRMAENLQELIGPYFLRRTKAEVQSKELHAKQLRDNKENDPTVGNLDQRIQIEMPTLTRKNDLIVWVYLSPVQEQIYRDFQNLDDIKELLDST----------RSPLVALGILKKICVHPRLLPERACAQLGLITCEFFFR-IESEGLQSNWFLSSI----KNVPPKTLIEESGKLTFLIG---LLERLRQEGHRTLVFSQSLKMLDIIDHILKHQGFKV--MRIDGTITHITEREKRVQTFQKDSAFNVFLLTTQVGGVGLTLTAANRVVILDPSWNPATDAQAVDRAYRIGQTDNVIIYRLVTCGTMEEKIYRRQIFKESLIRQTTGDKKNPFRYFSQQELRELF 638          

Query: 3374 GAIELIY---LVCHSGLLPYRLAIAVIILPVVLACLNAPFDPLRRVATHVFSXXXXXXXXESSGADLSILTPARQQQRKQHLSFLDSLLNPKLIGQYNAHHSVVSAKLRQYQEEGVNWLGFLNRYGLHGVLADDMGLGKTLQAICVIAG---------EYSRA-PSTCPPSLIVCPPTLTVHWHQEFKKFLVNLPDFNTIVYLGTPMYRQCIFNSLSRYQVVITSYDTLRSDMNLLARPTFPRCGTDVTKGSLMANSNVWNYVVLDEGHLIRNYKSKVAVATRALCARHRLVLTGTPIQNRVGELWSLFDFLMPGLLGTCTEFNRRYGRVLEQNGSNSGRKVDSEAGTLALELLHRQVLPFMLRRVKDDVLQELPPKIMQDYMCTMSPLQLRLYTHCMESQAATDTDFVELVDKSYKENSAINQHRHGFQTMHYLRLVCNHPSLGLTSSHPLYRTLMRELAANNQCLDDINLSGKLVALRQLILDCGVGVSGAGEEELDETS----------VVASNRLLVFCQSIKMMELVDK-MIRNEIPKATHLRLDGSVPAKDRQQIVEKFSCDAXXXXXXXXXXXXXXXXXXXXANIVIFVEHDWNPMRDLQAMDRAHRIGQKHTVIVYRLITAQSIEEKIMNLQEFKKFLANAVVSKDNNQMASMNTENILEIMNKEANWPTQSPPASANGKQKVVSSVSGGTETQLGSKSVLSKISKADSGE--RVYDCLDEYDQEYNLDSFV 5515
            G+ ELIY   L   + +LPY   +  +I+P+ L  ++   + +R +AT  F+ ++ L+PLE+  AD   L       R++   F+  +++P     +    ++  A LR+YQ++GVNWL FLN+Y LHG+L DDMGLGKTLQ IC+IA          E +R+  S   PSLI+CPP+LT HW  EF ++    P    +VY G P  R  +   LS   +++TSYD  R+D+ +L                   N   +NY VLDEGH+I+N +SK+A A + + A HRL+LTGTPIQN V ELWSLFDFLMPG LGT   F  R+ + +  + ++     + EAG LALE LH+QVLPFMLRR+K+DVL +LPPKI+QDY C +  LQ +LY    + Q         +V+K  + +   +  +H FQ + Y+R +CNHP+L L+ +HP    +   L      L DI  + KL ALR L+ +CG+     GEE++D+ +          V++ +R L+FCQ   M+++V+  + +  +P  T++RLDGS+  +DRQ++V KF+ D SID LLLTT +GGLGLNLT A+ VIFVEHDWNPM DLQAMDRAHRIGQK  V VYR+IT  ++EEKIM LQ+FK  +A+ VV++ N+ +ASM+T  +L++ + + N  +Q      NG     S  + G E  + +++ L+  +K   GE   ++D   +Y++EYNLD+F+
Sbjct: 1170 GSTELIYHLSLSMETDVLPY---VIFLIVPL-LGRMSDSNEDVRNLATTTFASIIKLVPLEAGIADPKGLPEELVASRERERDFIQQMMDPSKAKPFKLPIAI-KATLRKYQQDGVNWLAFLNKYHLHGILCDDMGLGKTLQTICIIASDQYLRKEDYEKTRSVESRALPSLIICPPSLTGHWENEFDQYA---PFLKVVVYAGGPTVRLTLRPQLSDADIIVTSYDVARNDLAVL-------------------NKTEYNYCVLDEGHIIKNSQSKLAKAVKEITANHRLILTGTPIQNNVLELWSLFDFLMPGFLGTEKMFQERFAKPIAASRNSKTSSKEQEAGVLALEALHKQVLPFMLRRLKEDVLSDLPPKIIQDYYCELGDLQKQLYMDFTKKQK-------NVVEKDIENSEIADGKQHIFQALQYMRKLCNHPALVLSPNHPQLAQVQDYLKQTGLDLHDIINAPKLSALRTLLFECGI-----GEEDIDKKASQDQNFPIQNVISQHRALIFCQLKDMLDMVENDLFKKYMPSVTYMRLDGSIDPRDRQKVVRKFNEDPSIDCLLLTTKVGGLGLNLTGADTVIFVEHDWNPMNDLQAMDRAHRIGQKKVVNVYRIITKGTLEEKIMGLQKFKMNIASTVVNQQNSGLASMDTHQLLDLFDPD-NVTSQDNEEKNNGD----SQAAKGME-DIANETGLTGKAKEALGELKELWDP-SQYEEEYNLDTFI 1863          

Query:   86 SRLDKLFELLESNH-QNIRNAAAIQIGQLSANNQVNISALLAKLLPYAKHKIWVVRIAASDAVRHIGNNAKLW-------VPGTS---------------------ESNVTNVSNLI-------NLENLNLHDILKIGTRLYSRDFKDLD-----EANTNQNINRDELARHLGFLIPDECEIKNLITVKDCELVESKSENKMSVELAVMK------SMENSPKKPVKRPHEEVQDV--------------------NEPGTKMKCVEK--------------IGNETERERNTEWPWVDFCEELLKNLWDAKWEIRHGAATCLRELIRSQGSIMLPKNANISSTDKFAACHERFQEEIVVRLLCTLTLDQLSDFVSDEMVAPVRESCAQALGVISVHLTRRLVEILANQLLSLLNHDE---------WRVNHXXXXXXXXXXXXRMD------LVEVLLPIIYDPISSHLKGNXXXXXXXXXXXXLMPLFGDCCSNTVAISNEELDTLKTDLWDVLAVRIDCTTSGATCAVLQLLERL---YEKCNVVYNQSEDQP 1456
            SRLD+   L+E+   Q +RN AA Q+G L+  +  +I +LL+++ P+   K W  R+ A+ AV  I  +A  W       V GT+                     E+   N  NL+       +L +  L++ILK G  L +    D +     + N  +    D++ +    L   +   +N             + NK S  +  M       S +N+PK PV      V                       N+   K++  E+              +  + E      W +    E LL NL    WEIRHGAA  LREL++     +     N    +     + R  E++  RLL    LD+  D+V D +VAPVRES AQ L  + +HL   L   + N L  L+  D          W   HG LLG++Y ++ + +      L+E ++ I+   ++       DDDV+  A + L P+     S  V ++N  ++ L T +W +LA R+D   S +  +++ LL +L    E  +++ N++ + P
Sbjct:    6 SRLDRQVILIETGSTQVVRNMAADQMGDLAKQHPEDILSLLSRVYPFLLVKKWETRVTAARAVGGIVAHAPSWDPNESDLVGGTNEGSPLDNAQVKLEHEMKIKLEEATQNNQLNLLQEDHHLSSLSDWKLNEILKSGKVLLASSMNDYNVLGKADDNIRKQAKTDDIKQETSMLNASDKANEN-----------KSNANKKSARMLAMARRKKKMSAKNTPKHPVDITESSVSKTLLNGKNMTNSAASLATSPTSNQLNPKLEITEQADESKLMIESTVRPLLEQHEIVAGLVWQFQGIYELLLDNLMSENWEIRHGAALGLRELVKKHAYGVSRVKGNTREENNLR--NSRSLEDLASRLLTVFALDRFGDYVYDTVVAPVRESVAQTLAALLIHLDSTLSIKIFNCLEQLVLQDPLQTGLPNKIWEATHGGLLGIRYFVSIKTNFLFAHGLLENVVRIVLYGLN-----QSDDDVQSVAASILTPI----TSEFVKLNNSTIEILVTTIWSLLA-RLDDDISSSVGSIMDLLAKLCDHQEVLDILKNKALEHP 538          

Query: 3671 VVSAKLRQYQEEGVNWLGFLNRYGLHGVLADDMGLGKTLQAICVIAGEYSRAPSTCPPSLIVCPPTLTVHWHQEFKKFLVNLPDFNTIVYLGTPMYRQCIFNSL---SRYQVVITSYDTLRSDMNLLARPTFPRCGTDVTKGSLMANSNVWNYVVLDEGHLIRNYKSKVAVATRALCARHRLVLTGTPIQNRVGELWSLFDFLMPGLLGTCTEFNRRYGRVLEQNGSNSGRKVDSEAGTLALELLHRQVLPFMLRRVKDDVLQELPPKIMQDYMCTMSPLQLRLYTHCMESQAATDTDFVELVDKSYKENSAINQHRHG----FQTMHYLRLVCNHPSL--GLTSSHPLYRTLMRELAANNQCLDDINLSGKLVALRQLILDCGVGVSGAGEEELDETSVVASNRLLVFCQSIKMMELVDKMIRNEIPKATHLRLDGSVPAKDRQQIVEKFSC-DAXXXXXXXXXXXXXXXXXXXXANIVIFVEHDWNPMRDLQAMDRAHRIGQKHTVIVYRLITAQSIEEKIM 5212
            V S KLR YQ +G+NWL  L+   L G+LAD+MGLGKTLQ I  + G          P LI+ P +   +W +EF K+    P+ N +V  G    R  I  ++   +R+ V+ITSY+ +  + N L R                     W Y+V+DE H I+N +S ++   R   +++RL++TGTP+QN + ELW+L +FL+P + G    F+  +    EQN S   +++        ++ LH  + PF+LRRVK DV + L PKI  +    M+ +Q++ Y   +E     D D V         N A+ + R G       +  LR  CNHP L  G     P   T    L  N         SGK++ L +L+            + L E      +R+L+F Q  +++++++           + R+DGS   ++R + +++++  ++   + LLTT  GGLG+NL +A+ VI  + DWNP  DLQAMDRAHRIGQK  V VYR +T  +IEEK++
Sbjct:  179 VKSGKLRDYQVQGLNWLISLHENKLSGILADEMGLGKTLQTISFL-GYLRYVKQIEGPFLIIVPKSTLDNWRREFLKWT---PNVNVLVLHGDKDTRADIVRNIILEARFDVLITSYEMVIREKNALKRL-------------------AWQYIVIDEAHRIKNEQSALSQIIRLFYSKNRLLITGTPLQNNLHELWALLNFLLPDIFGDSELFDEWF----EQNNSEQDQEI-------VIQQLHSVLNPFLLRRVKADVEKSLLPKIETNVYVGMTDMQIQWYKSLLEK----DIDAV---------NGAVGK-REGKTRLLNIVMQLRKCCNHPYLFEGAEPGPPY--TTDEHLIFN---------SGKMIILDKLL------------KRLKE----KGSRVLIFSQMSRLLDILEDYCY--FRDFEYCRIDGSTSHEERIEAIDEYNKPNSEKFVFLLTTRAGGLGINLVTADTVILFDSDWNPQADLQAMDRAHRIGQKKQVHVYRFVTENAIEEKVI 625          

Query: 3596 RKQHLSFLDSLLNPKLIGQYNAHHSVVSAKLRQYQEEGVNWLGFLNRYGLHGVLADDMGLGKTLQAICVIAGEYSRAPSTCPPSLIVCPPTLTVHWHQEFK----------------------KFLVNLPDFNTIVYLGTP--MYRQCIFNSLSRYQVVITSY------DTLRSDMNLLARPTFPRCGTDVTKGSLMANSNVWNYVVLDEGHLIRNYKSKVAVATRALCARHRLVLTGTPIQNRVGELWSLFDFLMPGLLGTCTEFNRRYGRVLEQNGSNSGRKVDSEAGTLALELLHRQVLPFMLRRVKDDVLQELPPKIMQDYMCTMSPLQLRLYTHCMESQAATDTDFVELVDKSYKENSAINQHRHGFQTMHY----LRLVCNHPSLGLTSSHPLYRTLMRELAANNQCLDDINLSGKLVALRQLILDCGVGVSGAGEEELDETSVVASNRLLVFCQSIKMMELVDKMIRNEIPKATH---LRLDGSVPAKDRQQIVEKFSCDAXXXXXXXXXXXXXXXXXXXXANIVIFVEHDWNPMRDLQAMDRAHRIGQKHTVIVYRLITAQSIEEKIMNLQEFKKFLANAVVS 5257
            R+ H +  D+ LN     Q+     + S  L  YQ+  V WL  L +    G++ D+MGLGKT+Q I  IA  +     T P  LIVCP T+   W  EF+                      KF ++  D   ++    P     +   NS    + + +SY      D + +D ++L   T+   G  +    L+     W Y VLDEGH IRN  S++++  + L   +R++L+GTPIQN + ELWSLFDF+ PG LGT   F +++   +   G  +   +  + G      L   + P++LRRVK DV ++LP K      C ++  Q   Y   + S                   S +NQ ++G + + +    LR +CNHP L           L R+   +N    D   SGK+  ++QL+L                       + L+F QS +M++++++ I  + P  +H   LR+DG+   K RQ +V++F+ ++    LL T   G       +  I+IF + DWNP  D+QA +RA RIGQK  V +YRL+   SIEEKI + Q FK+FL N +++
Sbjct:  272 RRPHPNIPDAKLN----SQFKIPGEIYSL-LFNYQKTCVQWLYELYQQNCGGIIGDEMGLGKTIQVIAFIAALHHSGLLTGPV-LIVCPATVMKQWCNEFQHWWPPLRTVILHSMGSGMASDQKFKMDENDLENLIMNSKPSDFSYEDWKNSTRTKKALESSYHLDKLIDKVVTDGHILI-TTY--VGLRIHSDKLLKVK--WQYAVLDEGHKIRNPDSEISLTCKKLKTHNRIILSGTPIQNNLTELWSLFDFIFPGKLGTLPVFQQQFVIPINIGGYANATNIQVQTGYKCAVALRDLISPYLLRRVKADVAKDLPQKKEMVLFCKLTKYQRSKYLEFLHS-------------------SDLNQIQNGKRNVLFGIDILRKICNHPDL-----------LDRDTKRHNPDYGDPKRSGKMQVVKQLLL----------------LWHKQGYKALLFTQSRQMLDILEEFISTKDPDLSHLNYLRMDGTTNIKGRQSLVDRFNNESFDVFLLTTRVGGLGVNLTGANRIIIF-DPDWNPSTDMQARERAWRIGQKREVSIYRLMVGGSIEEKIYHRQIFKQFLTNRILT 804          

Query: 3671 VVSAKLRQYQEEGVNWLGFLNRYGLHGVLADDMGLGKTLQAICVIAGEYSRAPSTCPPSLIVCPPTLTVHWHQEFKKFLVNLPDFNTIVYLGTPMYRQCIFNSL--SRYQVVITSYDTLRSDMNLLARPTFPRCGTDVTKGSLMANSNVWNYVVLDEGHLIRNYKSKVAVATRA-LCARHRLVLTGTPIQNRVGELWSLFDFLMPGLLGTCTEFNRRYGRVLEQNGSNSGRKVDSEAGTLALELLHRQVLPFMLRRVKDDVLQELPPKIMQDYMCTMSPLQLRLYTHCMESQAATDTDFVELVDKSYKENSAINQHRHGFQT-MHYLRLVCNHPSLGLTSSHPLYRTLMRELAANNQCLDDI-NLSGKLVALRQLILDCGVGVSGAGEEELDETSVVASNRLLVFCQSIKMMELVDKMIRNEIPKATHLRLDGSVPAKDRQQIVEKFSC-DAXXXXXXXXXXXXXXXXXXXXANIVIFVEHDWNPMRDLQAMDRAHRIGQKHTVIVYRLITAQSIEEKIMNLQEFKKFLANAVV---SKDNNQMASMNTENIL 5302
            +V   L+ YQ +G+ W+  L    L+G+LAD+MGLGKT+Q I ++   Y    +   P L++ P +   +W  EF K+    P   TI + G+P  R+     +    + VV+T+++ +  +  LL++                     W ++++DEGH ++N +SK+++       A +RL+LTGTP+QN + ELW+L +F++P +  +   F+  +       G     ++  E   L +  LH+ + PF+LRR+K DV +ELP K+ +   C MS LQ  +Y   ++ +       + + D++ K+   +     GF   +  L+ +CNHP         ++  +  ++    +  DDI  ++GK   L +++    +  +G              +R+L+F Q  ++M++++  +R       +LRLDG   + +R +++  F+  D+     +L+T  GGLGLNL +A+ VI  + DWNP +DLQA DRAHRIGQK+ V + RLIT  S+EE I+  + +KK   +  V    K +N+  S   E +L
Sbjct:  762 LVGGTLKDYQIKGLQWMVSLFNNHLNGILADEMGLGKTIQTISLLTYLYE-MKNIRGPYLVIVPLSTLSNWSSEFAKWA---PTLRTISFKGSPNERKAKQAKIRAGEFDVVLTTFEYIIKERALLSKVK-------------------WVHMIIDEGHRMKNAQSKLSLTLNTHYHADYRLILTGTPLQNNLPELWALLNFVLPKIFNSVKSFDEWFNTPFANTGGQDKIELSEEETLLVIRRLHKVLRPFLLRRLKKDVEKELPDKVEKVVKCKMSALQQIMYQQMLKYRR------LFIGDQNNKKMVGL----RGFNNQIMQLKKICNHPF--------VFEEVEDQINPTRETNDDIWRVAGKFELLDRIL--PKLKATG--------------HRVLIFFQMTQIMDIMEDFLR--YINIKYLRLDGHTKSDERSELLRLFNAPDSEYLCFILSTRAGGLGLNLQTADTVIIFDTDWNPHQDLQAQDRAHRIGQKNEVRILRLITTNSVEEVILE-RAYKKLDIDGKVIQAGKFDNKSTSEEQEALL 1254          

Query: 3686 LRQYQEEGVNWLGFLNRYGLHGVLADDMGLGKTLQAICVIAGEYSRAPSTCPPSLIVCPPTLTVHWHQEFKKFLVNLPDFNTIVYLGTPMYRQ------CIFNSLSRYQVVITSYDTLRSDMNLLARPTFPRCGTDVTKGSLMANSNVWNYVVLDEGHLIRNYKSKVAVATRALCARHRLVLTGTPIQNRVGELWSLFDFLMPGLLGTCTEFNR--RYGRVLEQNGSNS---GRKVDSEAGTLALELLHRQVLPFMLRRVKDDVLQE-LPPKIMQDYMCTMSPLQLRLYTHCMESQAATDTDFVELVDKSYKENSAINQHRHGFQTMHYLRLVCNHPSLGLTSS---HPLYRTL--MRELAANNQCLDDIN--LSGKLVALRQLI-----------------LDCGVGVSGAGE--EELDETSVVASNRLLVFCQSIKMMELVDKMIRNEIPKATHLRLDGSVPAKDRQQIVEKF-SCDAXXXXXXXXXXXXXXXXXXXXANIVIFVEHDWNPMRDLQAMDRAHRIGQKHTVIVYRLITAQSIEEKIMNLQEFKKFLANAVVSKDNNQMASMN 5287
            L+ YQ EG+NWL  L   GL+G+LAD+MGLGKT+Q+I ++A  Y     T  P L+  P +   +W  EF KF    PD   + Y GT  Y++        F       +VITSY+ +  D +L+                    S  W ++++DEGH ++N   ++    + +   +RL+LTGTP+QN + ELWSL +F+MP +      FN+   +  +   +GSNS    + ++ E     +  LH  + PF+LRR+K  VL   LPPK      C M+  Q + Y   +  +    T F EL+    K+   +N    G  +   +R   N+   G  +S   + +  TL  M +L   N  ++  N  L   ++ LRQ+I                 L+  +  SG  +  ++L    +   +++L++ Q + M++L++     ++      R+DGSV  + R+  +EKF S     +I LL+T   GLG+NL  A+ V+  + DWNP  DLQAMDR HRIGQ+  VIVYRL    +IE  I+     K+ L   V+     QM   N
Sbjct:  222 LKPYQLEGLNWLITLYENGLNGILADEMGLGKTVQSIALLAFIYEM--DTKGPFLVTAPLSTLDNWMNEFAKFA---PDLPVLKYYGTNGYKERSAKLKNFFKQHGGTGIVITSYEIILRDTDLIM-------------------SQNWKFLIVDEGHRLKNINCRLIKELKKINTSNRLLLTGTPLQNNLAELWSLLNFIMPDIFADFEIFNKWFDFDSLNLGSGSNSEALNKLINDELQKNLISNLHTILKPFLLRRLKKVVLANILPPKREYIINCPMTSAQEKFYKAGLNGKLKK-TMFKELI----KDFFTLNDEYIGHVSNRSIRDFINYKLSGNETSNTDNKINPTLLQMDKLYKKNLQMEISNKKLQNMMMQLRQIIDSTFLFYFPYLHPEDLTLETLLKTSGKLQILQKLIPPLISEGHKVLIYSQFVNMLDLIEDWC--DLNSFATFRIDGSVNNETRKDQLEKFNSSKDKHNIFLLSTRAAGLGINLVGADTVVLFDSDWNPQVDLQAMDRCHRIGQESPVIVYRLCCDNTIEHVILTRAANKRNLERMVI-----QMGKFN 758          

Query: 3458 VLACLNAPFDPLRRVATHVFSXXXXXXXXESSGADLSILTPARQQQRKQHLSFLDSLLNPKLIGQYNAHHSVVSAKLRQYQEEGVNWLGFLNRYGLHGVLADDMGLGKTLQAICVIAG----------EYSRAPSTCPPSLIVCPPTLTVHWHQEFKKFLVNLPDFNTIVYLGTPMYRQCIFNSLSRYQVVITSYDTLRSDMNLLARPTFPRCGTDVTKGSLMANSNVWNYVVLDEGHLIRNYKSKVAVATRALCARHRLVLTGTPIQNRVGELWSLFD--FLMPGLLGTCTEFNRRYGRVLEQNGSNSGRKVDSEAGTLALELLHRQVLPFMLRRVKDDVLQELPPKIMQDYMCTMSPLQLRLYTHCMESQA--ATDTDFVELVDKSYKENSAINQHRHGFQTMHYLRLVCNHPSLGLTSSHPLYRTLMRELAANNQCLDDINLSGKLVALRQLILDCGVGVSGAGEEELDETSVVASNRLLVFCQSIKMMELVDK-MIRNEIPKATHLRLDGSVPAKDRQQIVEKFSCDAXXXXXXXXXXXXXXXXXXXXANIVIFVEHDWNPMRDLQAMDRAHRIGQKHTVIVYRLITAQSIEEKIMNLQEFKKFLANAVVSKDNNQMASMNTENILEI--MNKEANWPTQSPPASANGKQKVVSSVSGGTETQLGSKSVLSKISKADSGERVYDCLDEYDQEYNLDSFV 5515
            +L  ++   + +R +AT+ F+ L++L+PLE    D   +  +  +Q++   +FL+ LL+ K +  Y     +  A+LR+YQ++GVNWL FL++Y LHG+L DDMGLGKTLQ+IC++A           E   A     PSL++CPPTLT HW  E +KF++       + Y G PM RQ + N +  + +++ SYD +R+D +                      S  WNY +LDEGH+I+N K+K+A   + L A HRL+L+GTPIQN V ELWSL    + +P +L   T F       L Q+        + EAG LA+E LHRQVLPF+LRR+K+DVLQ+LPPKI+QDY C +SPLQ++LY    +SQA    +  F    D   KE ++     H FQ + YLR VCNHP L LT  HP +  +M++L    Q L DI+ + KLVAL+QL+LDCG+GVS +   +L    VV+ +R+L+FCQ   M+++V+  + +  +P  T+LRLDGS PA  R  IV +F+ D SID+LLLTT +GGLGLNLT A+ VIFVEHDWNPM+DLQAMDRAHRIGQK  V VYRL+T  ++EEKIM LQ+FK  +AN V+S+DN+ +++M+T  + ++  ++KE     Q   A  N K+K+  SV    E                 GE ++D  ++Y+ EYNLD+F+
Sbjct: 1207 ILGRMSDQTEDVRLLATNCFATLISLMPLEKGVPDPPDMPASLVEQKQIERTFLEQLLDSKKLQNYTISIPI-KAELRKYQQDGVNWLAFLSKYKLHGILCDDMGLGKTLQSICIMASDHHYKLQKYKETGHADCKPLPSLVICPPTLTGHWVYEVEKFVIK-EYLKPLHYTGPPMERQRLRNKVKNHNLIVASYDIVRNDGDFF-------------------KSIHWNYCILDEGHIIKNGKTKLARVIKQLRANHRLILSGTPIQNNVLELWSLLHSFYWIPFILYNNTHFQENIDMCLIQSRDAKSSSKEQEAGALAMESLHRQVLPFLLRRLKEDVLQDLPPKIIQDYYCELSPLQVQLYEDFAKSQAKKGLEESFSLSEDADDKEMASKKGSAHIFQALQYLRKVCNHPLLVLTPQHPEHDKIMQQLKETRQSLKDIHHAAKLVALKQLLLDCGIGVSTSSTSDLASEPVVSQHRVLLFCQLKSMLDIVENDLFKTNMPSVTYLRLDGSTPAGSRHSIVHRFNNDPSIDVLLLTTHVGGLGLNLTGADTVIFVEHDWNPMKDLQAMDRAHRIGQKKVVNVYRLVTKGTLEEKIMGLQKFKMTIANTVISQDNSSLSTMDTGQLFDLFTVDKEGKREEQH-EAQDNNKRKM--SVKNAIEGM---------------GE-LWD-EEQYETEYNLDNFI 1868          

Query:  137 RNAAAIQIGQLSANNQVNISALLAKLLPYAKHKIWVVRIAASDAVRHIGNNAKLWVPG--TSESNVTNVSNLINLE-------NLNLHDILKIGTRLYSRDFKDLD---------EANTNQNINRDELARHLGF-LIP----------DECEIKNLITVKDCELVESKSENK-------MSVELAVMKSMENSP--------------KKPVKRPHEEVQDVNEPGTKMK-------CVEK--------IGNETE----RERNTEWPWVDFCEELLKNLWDAKWEIRHGAATCLRELIRSQGSIMLPKNANISSTDKFAACHE---RFQEEIVVRLLCTLTLDQLSDFVSDEMVAPVRESCAQALGVISVHLTRRLVEILANQLLSLLNHDEWRVNHXXXXXXXXXXXXRMDLVEVLLPIIYDPISSHLKGNXXXXXXXXXXXXLMPLFGDCCSNTVAISNEELDTLKTDLWDVLAVRIDCTTSGATCAVLQLLERLYEKCNVVYNQSEDQPMATDRVKALNEYINRLHWCYFNYS-DLVRLAAVRTCRAVLQSIG-IKVGT---ILEHGTIXXXXXXXXXXXXIDDNCQVAAEAHSVWNQFIDSLPEQLLARVSCERLEIWMCSAMQP 1792
            R AAA Q+G++   +   +  LL+++  + K   W  RIAA  A+  I  +   W P   T ++   + S+L   E         ++  +L+ G  L      + D         +      + +  + + LG  +IP          D+ ++  L++V+D     +K +N        ++ E+A + S + S               K+  K   + V + +E G  +K        VE+        + N T+     E + EWP+   C+EL + L    WE+RHGAAT LRE+++  G     + A  +        H    ++ E + V LLC L LD+  DFVSDE+VAPVRE+CAQ LGV+  H+       +   LL+L    EW V HG LLG+KYLLA R DL   LLP++ +PI S L+ + DDDVR  A +AL+P+      + V ++  ++  L   LW+ L    D T S  T +++ LL  +    +V                +L++ + RL W +  ++   VRLAA+RT R +LQ    +  GT   +     +   +  + QR +++ +  V    + VW   +    +Q L+      L  W+   MQP
Sbjct:   33 RKAAAKQLGEVQKLHPHELPNLLSRVHTFLKSGNWDTRIAAGQAIEAIAQSVPQWEPPGLTVKAEPQDGSSLCGSEPEQLEFGKFDIKRVLQHGEPLVGSSGAEYDMPDDELAGLDPKEKLALQQRMVRKRLGLDIIPGLDVGMDKLFDDEDL--LMSVEDTRRKPAKKQNSFESAADVVAAEIAAISSSKMSAREKNRAKRKAKLLAKQRSKEAGDSVSNEDEDGPNVKKRKTASVVVEQPAHADKIVVDNVTDVAATFEESGEWPFEHXCQELSQELXHHSWEVRHGAATGLREIVKVHG-----QGAGKTVDTFLEEMHMQNMKWMENMAVYLLCVLALDRFGDFVSDEVVAPVRETCAQTLGVVVRHMNVSDCRSVMLTLLTLQEQTEWEVRHGGLLGIKYLLAVRQDLSADLLPLVLNPIISALQ-DDDDDVRAIAASALLPI----AESIVQLAPNKVQELLMTLWNTLVELDDLTAS--TNSIMLLLAGILACPSVSMTM-------FGSAGSLSDLVPRL-WPFLRHTIRSVRLAALRTLRILLQGTANVSSGTAECVWLTPILQDAVRHIYQRFILESDASVIQYVYEVWCDLLSKSSKQCLSSSILPYLNSWLGMMMQP 639          

Query: 3671 VVSAKLRQYQEEGVNWLGFLNRYGLHGVLADDMGLGKTLQAICVIAGEYSRAPSTCPPSLIVCPPTLTVHWHQEFKKFLVNLPDFNTIVYLGTPMYRQCIFNSL--SRYQVVITSYDTLRSDMNLLARPTFPRCGTDVTKGSLMANSNVWNYVVLDEGHLIRNYKSKVA-VATRALCARHRLVLTGTPIQNRVGELWSLFDFLMPGLLGTCTEFNRRYGRVLEQNGSNSGRKVDSEAGTLALELLHRQVLPFMLRRVKDDVLQELPPKIMQDYMCTMSPLQLRLYTHCMESQAATDTDFVELVDKSYKENSAINQHRHGFQTMHYLRLVCNHPSLGLTSSHPLYRTLMRELAANNQCL---DDINLSGKLVALRQLILDCGVGVSGAGEEELDETSVVASNRLLVFCQSIKMMELVDKMIR-NEIPKATHLRLDGSVPAKDRQQIVEKFSC-DAXXXXXXXXXXXXXXXXXXXXANIVIFVEHDWNPMRDLQAMDRAHRIGQKHTVIVYRLITAQSIEEKIMNLQEFKKFLANAVVSK---DNNQMASMNTENILEIMNKEANWPTQSPPASANG 5362
            +V  +L++YQ  G+ W+  L+   L+G+LAD+MGLGKT+Q I + +    +      P L++ P +   +W  EF+K+    P    + Y G+P  R+     L   ++ VV+T+Y+ +  D  +LA+                     W Y+V+DEGH ++N+  K+  V      A+HR++LTGTP+QNR+ ELW+L +FL+P +  + + F + +       G     +++ E   L +  LH+ + PF+LRR+K +V  +LP K+     C MS LQ  LY H  +         V L D S K+       +    T+  LR +CNHP +       +  ++   L  +   +   D    SGK   L +++                       +R+L+FCQ   +M +++        P   +LRLDG+  ++DR Q++  F+  D+   + LL+T  GGLGLNL +A+ V+  + DWNP +DLQA DRAHRIGQ+  V V RL+T  S+EEKI+    +K  +   V+     + N  +S     ++ +++ E N   ++P +++NG
Sbjct:  641 LVGGRLKEYQLAGLEWMVSLHNNNLNGILADEMGLGKTIQTIALFSYLIEKK-RLNGPFLVIVPLSTLSNWQLEFEKWA---PSAIVVSYKGSPNMRRSAGAVLRTGKFNVVLTTYEYVMRDKAILAKVR-------------------WKYMVVDEGHRMKNHHCKLTQVLNTHYAAQHRILLTGTPLQNRLPELWALLNFLLPTIFKSVSTFEQWFNAPFAMTGEKV--ELNEEETILIIRRLHKVLRPFLLRRLKKEVESQLPDKVEYVVKCDMSILQRILYNHMYKK-------GVLLTDGSEKDKKGKGGTKTLMNTIMQLRKICNHPFM----FQHIEESIAEHLGFHGGIVTGPDIYRASGKFELLDRILPKLKRN----------------KHRVLMFCQMTSLMTILEDYFNWKGFP---YLRLDGTTKSEDRGQLLSLFNAKDSPYFVFLLSTRAGGLGLNLQAADTVVIFDSDWNPHQDLQAQDRAHRIGQEKEVRVLRLMTVNSVEEKILAAARYKLNVDEKVIQAGMFNQNSTSSERKAFLMALLDTE-NDDDEAPKSNSNG 1159          

Query: 3671 VVSAKLRQYQEEGVNWLGFLNRYGLHGVLADDMGLGKTLQAICVIAGEYSRAPSTCP-PSLIVCPPTLTVHWHQEFKKFLVNLPDFNTIVYLGTPMYRQCIFNSL---SRYQVVITSYDTLRSDMNLLARPTFPRCGTDVTKGSLMANSNVWNYVVLDEGHLIRNYKSKVAVATRALCARHRLVLTGTPIQNRVGELWSLFDFLMPGLLGTCTEFNRRYGRVLEQNGSNSGRKVDSEAGTLALELLHRQVLPFMLRRVKDDVLQELPPKIMQDYMCTMSPLQLRLYTHCMESQAATDTDFVELVDKSYKENSAINQHRHGFQTMHYLRLVCNHPSL-GLTSSHPLYRTLMRELAANNQCLDDINL---SGKLVALRQLILDCGVGVSGAGEEELDETSVVASNRLLVFCQSIKMMELVDK--MIRNEIPKATHLRLDGSVPAKDRQQIVEKFSC-DAXXXXXXXXXXXXXXXXXXXXANIVIFVEHDWNPMRDLQAMDRAHRIGQKHTVIVYRLITAQSIEEKIMNLQEFKKFLANAVVSK 5260
            +   ++R YQ  G+NWL  L   G++G+LAD+MGLGKTLQ I ++   Y +     P P +++CP +   +W  EF+++    P    +  +G    R            + V +TSY+     M +  +  F +                W Y+V+DE H I+N KSK++   R L + +RL+LTGTP+QN + ELW+L +FL+P +  +  +F+  +         NS   V+ +     +E LH  + PF+LRR+K DV + L PK        ++ +Q   YT  +      D D V    K+ K              +  LR  CNHP L       P Y T             D++L   SGK+  L +L+    +   G+              R+L+F Q  +++++++   + R    +  + RLDG  P ++RQ  +  F+   ++  I +L+T  GGLG+NL +A+IVI  + DWNP  DLQAMDRAHRIGQK  V V+R I+  ++EE+I+   E K  L   V+ +
Sbjct:  139 IKGGEMRDYQVRGLNWLISLYENGINGILADEMGLGKTLQTISLLG--YMKNFRNVPGPHMVICPKSTLANWMAEFERWC---PSIRAVCLIGNQEQRTAFIRDTMLPGEWDVCVTSYE-----MVIREKAVFKKFA--------------WRYIVIDEAHRIKNEKSKLSEIVRELRSANRLLLTGTPLQNNLHELWALLNFLLPDVFSSSDDFDAWF---------NSNNLVEEKQ---LVERLHSVLRPFLLRRLKSDVEKRLLPKKETKVYTGLTKMQRSWYTKIL----MKDIDVVNGAGKTDK--------MRLLNILMQLRKCCNHPYLFDGAEPGPPYTT-------------DVHLIENSGKMRVLDKLL--ARLKQEGS--------------RVLIFSQMTRLLDILEDYCLWR----QYDYCRLDGQTPHEERQAYINSFNMPGSTKFIFMLSTRAGGLGINLATADIVILYDSDWNPQVDLQAMDRAHRIGQKKQVKVFRFISESTVEERIIERAEMKLRLDAVVIQQ 598          

Query: 3686 LRQYQEEGVNWLGFLNRYGLHGVLADDMGLGKTLQAICVIAGEYSRAPSTCPPSLIVCPPTLTVHWHQEFKKFLVNLPDFNTIVYLGTPMYRQCIFNSLSRYQ---------VVITSYDTLRSDMNLLARPTFPRCGTDVTKGSLMANSNVWNYVVLDEGHLIRNYKSKVAVATRALCARHRLVLTGTPIQNRVGELWSLFDFLMPGLLGTCTEFNRRYG-RVLEQNGSNSGRKVDSEAGTLALELLHRQVLPFMLRRVKDDVLQELPPKIMQDYMCTMSPLQLRLYTHCMESQAATDTDFVELV--DKSYKEN-----SAINQHRHGFQTMHYLRLVCNHPSL-GLTSSHPLYRTLMRELAANNQCLDDINLSGKLVALRQLILDC------------GVGVSGAGEEELDETS---------VVASNR----LLVFCQSIKMMELVDKMIRNEIPKATHLRLDGSVPAKDRQQIVEKFSCDAXXXXXXXXXXXXXXXXXXXXANIVIFVEHDWNPMRDLQAMDRAHRIGQKHTVIVYRLITAQSIEEKIMNLQEFKKFLANAVVSK 5260
            LR YQ EGV WL  L   G++G+LAD+MGLGKT+Q I +++  Y        P L+  P +   +W  EF++F   +P    I+Y G+   R  +   +++ +         VV+TSY+   +D   L +              LM     W ++++DEGH I+N   ++    ++  + +RL+LTGTP+QN + ELWSL +FL+P +      F R +    +   G N  + +  E     LE LH  + PF+LRR+K DV   LPPK        ++  Q   Y      +AA D   +++V  +K  KE+     S   + R G + ++Y      + S+  L           RE+   +Q     ++S K+  +  L+  C             V      +EEL   S         V A  R    +L+F Q  KM++++       +    + RLDGS+  +DR++ ++ F+ D    I LL+T  GGLGLNL++A+ VI  + DWNP  DLQA DR HRIGQ   ++VYRL+T+ ++++KI+     K+ L   V+ K
Sbjct:  298 LRSYQLEGVEWLKGLYENGVNGILADEMGLGKTIQCIGLVS--YLIEMGVRGPFLVAAPLSTLPNWVSEFRRFSPQIP---VILYHGSIQERTSLRRKITKLKKAGPFETMPVVVTSYEIAMNDQKHLFQ--------------LM-----WKHMIVDEGHRIKNLNCRLIRELKSYNSANRLLLTGTPLQNNLAELWSLLNFLLPDIFDDLNSFQRWFDFSAINDEGGNE-KIIAQEKEHQVLERLHSILTPFLLRRLKTDVELSLPPKKEVLVRAPLTSKQTEFY------RAALDKTILDIVGDNKDKKEDKVEISSTGRKKRKGRRNINYKIFDDENGSIEELAEELATLEKSRREICTPSQKSSTYDISIKITNILMLLRKCCNHPYLLEYPLDPVTQQYKIDEELVRCSGKMLLLDQMVPALKRRGHKILIFSQMTKMLDILQDYCY--LRGYQYSRLDGSMKVEDRREEIDAFASDPEKFIFLLSTRAGGLGLNLSAADTVIIYDSDWNPQSDLQAQDRCHRIGQTKPILVYRLVTSNTVDQKIVERAASKRKLEKMVIYK 832          

Query: 3671 VVSAKLRQYQEEGVNWLGFLNRYGLHGVLADDMGLGKTLQAICVIAGEYSRAPSTCPPSLIVCPPTLTVHWHQEFKKFLVNLPDFNTIVYLGT----PMYRQCIFNSLSRYQVVITSYDTLRS---DMNLLA--RPTFPRCGTDVTKGSLMANSNVWNYVVLDEGHLIRNYKSKVAVATRALCARHRLVLTGTPIQNRVGELWSLFDFLMPGLLGTCTEFNRRYGRVLEQNGSNSGRKVDSEAGTLALELLHRQVLPFMLRRVKDDVLQELPPKIMQDYMCTMSPLQLRLYTHCMESQAATDTDFVELVDKSYKENSAINQHRHGFQTMHYLRLVCNHPSL--------GLTSSHPLY-----------------RTLMRELAANNQCLDDINLSGKLVALRQLILDCG-VGVSGAGEEELDETSVVASNRLLVFCQSIKMMELVDKMIRNEIPKATHLRLDGSVPAKDRQQIVEKFSCDAXXXXXXXXXXXXXXXXXXXXANIVIFVEHDWNPMRDLQAMDRAHRIGQKHTVIVYRLITAQSIEEKIMNLQEFKKFLANAVVSKDNNQ 5272
            + +  L+ YQ  G+NWL  ++  G++G+LAD+MGLGKT+QAI  IA    +      P LI+ P +   +W +EFK++    P     +Y G+       R+ I +  S ++V+IT+Y+       D + L   RP                     +YVV DEGH+++N +S+  +    + A+ RL+LTGTP+QN + EL SL  F+MP +    T+     G  L        R  DS       E   + + PF+LRR+K DVLQELP K      C +S  Q  L++              +L+ K Y E    ++ R     +  LR++ NHP L         L      Y                  T+M +   +  CL+  +LS  ++   +L+ D G      A   E+ +      +R+L+F Q   +M++++  +++      + RLDG  P  +RQ +++ F+ D  I + LL+T  GGLG+NLTSAN+VI  + D+NP  D QA DR HR+GQ   V VYRLI   ++E+ ++     K  L   VVS DN++
Sbjct:  108 IRAKSLKPYQLTGLNWLILMHEQGVNGILADEMGLGKTVQAISFIAHLIEKGDDG--PHLIIVPSSTLNNWVKEFKQWC---PTIRFTLYYGSQEERTYLREEILDEHSDFKVIITTYNMATGGFEDTSFLRQLRP---------------------HYVVFDEGHMLKNMQSQRYLKLTRIRAKRRLLLTGTPMQNDLLELMSLLSFVMPTIFDGRTD-----GLKLLFGNKKLDRDADSGYIKERAEQAKKIMKPFVLRRLKKDVLQELPQKHEHVIHCELSTSQKDLHS--------------KLMLKCYNEYRDASKSRDYKNILMALRMMSNHPLLLRNYYKDETLREMAVKYCRDIENRGSEVDLVCEDMTVMSDFELHRLCLEQRSLSSYVLG-EELLYDSGKFERLNAMLPEMKDNG----DRVLLFSQFTLVMDIIEVYLQH--CGYRYFRLDGQTPVVERQPMIDNFNSDPDIFLFLLSTKAGGLGINLTSANVVILHDIDFNPYNDKQAEDRCHRVGQTRDVHVYRLIAKDTVEDNMLKCANSKLKLEKDVVSADNDE 624          

Query: 3374 GAIELIYLVCHS---GLLPYRLAIAVIILPVVLACLNAPFDPLRRVATHVFSXXXXXXXXESSGADLSILTPARQQQRKQHLSFLDSLLNPKLIGQYNAHHSV-VSAKLRQYQEEGVNWLGFLNRYGLHGVLADDMGLGKTLQAICVIAGEY---------SRAPSTCP-PSLIVCPPTLTVHWHQEFKKFLVNLPDFNTIVYLGTPMYRQCIFNSLSRYQVVITSYDTLRSDMNLLARPTFPRCGTDVTKGSLMANSNVWNYVVLDEGHLIRNYKSKVAVATRALCARHRLVLTGTPIQNRVGELWSLFDFLMPGLLGTCTEFNRRYGRVLEQNGSNSGRKVDSEAGTLALELLHRQVLPFMLRRVKDDVLQELPPKIMQDYMCTMSPLQLRLYTHCMESQA-ATDTDFVELVD-KSYKENSAINQHRHGFQTMHYLRLVCNHPSLGLTSSHPLYRTLMRELAANNQCLDDINLSGKLVALRQLILDCGVGVSGAGEEELDETSVVASNRLLVFCQSIKMMELVD-KMIRNEIPKATHLRLDGSVPAKDRQQIVEKFSCDAXXXXXXXXXXXXXXXXXXXXANIVIFVEHDWNPMRDLQAMDRAHRIGQKHTVIVYRLITAQSIEEKIMNLQEFKKFLANAVVSKDNNQMASMNTENILEIMNKEANWPTQSPPASANGKQKVVSSVSGGTETQLGSKSVLSKISKADSGERVYDCLDEYDQEYNLDSFV 5515
            GAIE +  V       ++PY   I ++++PV L  ++ P D +R +AT  F+ L+ LLPLE+   D   ++    +Q+ +   FL+ LL+ + +  Y  H  V + A+LR+YQ++GVNWL FLN+Y LHG+L DDMGLGKTLQ+IC++AG++         ++A    P PSL+VCPPTLT HW  E  KF       + + Y G P  R  + + + ++ +++ SYD +R+D++      F                   NY +LDEGH+I+N K+K++ A + L A  RL+L+GTPIQN V ELWSLFDFLMPG LGT  +F  RYG+ +  +        + EAG LA+E LHRQVLPF+LRR+K+DVLQ+LPPKI+QDY C +SPLQ++LY    +S+A A+  D +     +  +E   +    H FQ + YLR +CNHPSL LT  HP Y+ +  +LAA N  L DI  + KL AL+QL+LDCG+G  G  E   +  +VVA +R+L+FCQ   M+++V+  +++ ++P  T+LRLDGSVPA  R  IV +F+ D SID+LLLTT +GGLGLNLT A+ V+FVEHDWNPMRDLQAMDRAHRIGQK  V VYRLIT  ++EEKIM LQ+FK  +AN V++++N  M SM T+ +L +   +            +GK +  SS SG        KSV+  +     GE ++D   +YD EYNLDSF+
Sbjct: 1106 GAIEALACVMEQLEVDIIPY---IVLLVVPV-LGRMSDPSDSIRFMATQCFATLIRLLPLEAGIPDPPAMSADLIRQKARERYFLEQLLDGRKLENY--HIPVPIKAELRKYQQDGVNWLSFLNKYKLHGILCDDMGLGKTLQSICILAGDHYLRAQEYAKTKAADCSPLPSLVVCPPTLTGHWVDEVGKFCTK-EYLHPLHYTGPPSERMRLQHQVKKHNLIVASYDVVRNDIDFFRNIKF-------------------NYCILDEGHIIKNGKTKLSKAIKQLAANFRLILSGTPIQNNVLELWSLFDFLMPGFLGTERQFAARYGKPILASRDAKSSSREQEAGVLAMEALHRQVLPFLLRRMKEDVLQDLPPKIIQDYYCNLSPLQVQLYEDFAKSRAKASVEDSISTASAEEEEEKPKLKATGHVFQALQYLRKLCNHPSLVLTPQHPEYKRVTDQLAAQNSGLRDIQHAPKLSALKQLLLDCGLGDGGGSETGTE--AVVAQHRVLIFCQLKSMLDIVEHDLLKPKMPTVTYLRLDGSVPAGLRHAIVSRFNNDPSIDVLLLTTHVGGLGLNLTGADTVVFVEHDWNPMRDLQAMDRAHRIGQKRVVNVYRLITRGTLEEKIMGLQKFKMSIANTVINQENTSMQSMGTDQLLNLFTLDQE--------EKDGKGEQSSSTSGKPSM----KSVIDGL-----GE-LWD-QQQYDTEYNLDSFM 1789          

Query:   86 SRLDKLFELLESNHQNI-RNAAAIQIGQLSANNQVNISALLAKLLPYAKHKIWVVRIAASDAVRHIGNNAKLWVPGTSE--------SNVTNVSNLINLENLNLHDILKIGTRLYSR---DFKDLDEANTNQNINRDELARH-------LGF------------LIPDE---------------------CEIKNLITVKDCELVESKSENKMSV-ELAVMKSMENSPKKPVKR---PHEEVQD-----------------VNEPGTKMKCVEKIGNETER--ERNTEWPWVDFCEELLKNLWDAKWEIRHGAATCLRELIRSQGSIMLPKNANISSTDKFAACHERFQEEIVVRLLCTLTLDQLSDFVSDE 976
            SRLD+LF LL++    + R AAA Q+G++   +   +  LLAK+L Y +   W  RIAA  AV  I  N   W P            S   + S+ ++  + ++  +LK G  L      +F +L E  T +   ++ LAR        LG             L  DE                     C   N +T++  EL++S+    MS  +    K M     K   R   P+E+  D                 +++P  + K +     +T    E ++EWP   FCEEL  +L++  WE+RHGA T LRE+++  G+         S+  + +  H+ + E++V+RLLC   LD+  DFVSDE
Sbjct:    4 SRLDRLFILLDTGTTPVTRKAAAQQLGEVVKLHPHELHNLLAKVLTYLRSPNWDTRIAAGQAVEAIVKNIPEWNPSPKPKEESCEDLSPEDSSSDRLSFYHFDISRLLKHGASLLGSAGAEF-ELQEDKTGEMDPKERLARQRKLLQKKLGLDMGAAIGMDTEELFNDEDLDDTCQSSVVKAHGVKVTAGCSSHNHLTIQAAELIDSEFRTGMSSRQKNKAKRMAKLVAKQRSRDVDPNEKSNDSFEGEPEEKRRKTTNVVIDQPAAQPKVLIDNVPDTSSVLEESSEWPLESFCEELCNDLFNPSWEVRHGAGTGLREILKCHGAAG--GKLVGSTAQQMSRQHQEWIEDLVIRLLCVFALDRFGDFVSDE 372          

Query: 3374 GAIELIYLVCHS---GLLPYRLAIAVIILPVVLACLNAPFDPLRRVATHVFSXXXXXXXXESSGADLSILTPARQQQRKQHLSFLDSLLNPKLIGQYNAHHSV-VSAKLRQYQEEGVNWLGFLNRYGLHGVLADDMGLGKTLQAICVIAGEY---------SRAPSTCP-PSLIVCPPTLTVHWHQEFKKFLVNLPDFNTIVYLGTPMYRQCIFNSLSRYQVVITSYDTLRSDMNLLARPTFPRCGTDVTKGSLMANSNVWNYVVLDEGHLIRNYKSKVAVATRALCARHRLVLTGTPIQNRVGELWSLFDFLMPGLLGTCTEFNRRYGRVLEQNGSNSGRKVDSEAGTLALELLHRQVLPFMLRRVKDDVLQELPPKIMQDYMCTMSPLQLRLYTHCMESQA-ATDTDFVELVD-KSYKENSAINQHRHGFQTMHYLRLVCNHPSLGLTSSHPLYRTLMRELAANNQCLDDINLSGKLVALRQLILDCGVGVSGAGEEELDETSVVASNRLLVFCQSIKMMELVD-KMIRNEIPKATHLRLDGSVPAKDRQQIVEKFSCDAXXXXXXXXXXXXXXXXXXXXANIVIFVEHDWNPMRDLQAMDRAHRIGQKHTVIVYRLITAQSIEEKIMNLQEFKKFLANAVVSKDNNQMASMNTENILEIMNKEANWPTQSPPASANGKQKVVSSVSGGTETQLGSKSVLSKISKADSGERVYDCLDEYDQEYNLDSFV 5515
            GAIE +  V       ++PY   I ++++PV L  ++ P D +R +AT  F+ L+ LLPLE+   D   ++    +Q+ +   FL+ LL+ + +  Y  H  V + A+LR+YQ++GVNWL FLN+Y LHG+L DDMGLGKTLQ+IC++AG++         ++A    P PSL+VCPPTLT HW  E  KF       + + Y G P  R  + + + ++ +++ SYD +R+D++      F                   NY +LDEGH+I+N K+K++ A + L A  RL+L+GTPIQN V ELWSLFDFLMPG LGT  +F  RYG+ +  +        + EAG LA+E LHRQVLPF+LRR+K+DVLQ+LPPKI+QDY C +SPLQ++LY    +S+A A+  D +     +  +E   +    H FQ + YLR +CNHPSL LT  HP Y+ +  +LAA N  L DI  + KL AL+QL+LDCG+G  G  E   +  +VVA +R+L+FCQ   M+++V+  +++ ++P  T+LRLDGSVPA  R  IV +F+ D SID+LLLTT +GGLGLNLT A+ V+FVEHDWNPMRDLQAMDRAHRIGQK  V VYRLIT  ++EEKIM LQ+FK  +AN V++++N  M SM T+ +L +   +            +GK +  SS SG        KSV+  +     GE ++D   +YD EYNLDSF+
Sbjct: 1165 GAIEALACVMEQLEVDIIPY---IVLLVVPV-LGRMSDPSDSIRFMATQCFATLIRLLPLEAGIPDPPAMSADLIRQKARERYFLEQLLDGRKLENY--HIPVPIKAELRKYQQDGVNWLSFLNKYKLHGILCDDMGLGKTLQSICILAGDHYLRAQEYAKTKAADCSPLPSLVVCPPTLTGHWVDEVGKFCTK-EYLHPLHYTGPPSERMRLQHQVKKHNLIVASYDVVRNDIDFFRNIKF-------------------NYCILDEGHIIKNGKTKLSKAIKQLAANFRLILSGTPIQNNVLELWSLFDFLMPGFLGTERQFAARYGKPILASRDAKSSSREQEAGVLAMEALHRQVLPFLLRRMKEDVLQDLPPKIIQDYYCNLSPLQVQLYEDFAKSRAKASVEDSISTASAEEEEEKPKLKATGHVFQALQYLRKLCNHPSLVLTPQHPEYKRVTDQLAAQNSGLRDIQHAPKLSALKQLLLDCGLGDGGGSETGTE--AVVAQHRVLIFCQLKSMLDIVEHDLLKPKMPTVTYLRLDGSVPAGLRHAIVSRFNNDPSIDVLLLTTHVGGLGLNLTGADTVVFVEHDWNPMRDLQAMDRAHRIGQKRVVNVYRLITRGTLEEKIMGLQKFKMSIANTVINQENTSMQSMGTDQLLNLFTLDQE--------EKDGKGEQSSSTSGKPSM----KSVIDGL-----GE-LWD-QQQYDTEYNLDSFM 1848          

Query:   86 SRLDKLFELLESNHQNI-RNAAAIQIGQLSANNQVNISALLAKLLPYAKHKIWVVRIAASDAVRHIGNNAKLWVPGTSE--------SNVTNVSNLINLENLNLHDILKIGTRLYSR---DFKDLDEANTNQNINRDELARH-------LGF------------LIPDE---------------------CEIKNLITVKDCELVESKSENKMSV-ELAVMKSMENSPKKPVKR---PHEEVQD-----------------VNEPGTKMKCVEKIGNETER--ERNTEWPWVDFCEELLKNLWDAKWEIRHGAATCLRELIRSQGSIMLPKNANISSTDKFAACHERFQEEIVVRLLCTLTLDQLSDFVSDEMVAPVRESCAQALGVISVHLTRRLVEILANQLLSLLNHDEWRVNHXXXXXXXXXXXXRMDLVEVLLPIIYDPISSHLKGNXXXXXXXXXXXXLMPLFGDCCSNTVAISNEELDTLKTDLWDVLAVRIDCTTSGATCAVLQLLERLYEKCNVVYNQSEDQPMATDRVKALNEYINRLHWCYFNYS-DLVRLAAVRTCRAVL----QSIGIKVGTILEHGTIXXXXXXXXXXXXIDDNCQVAAEAHSVWNQFIDSLPEQLLARVSCERLEIWMCSAMQPARLSYTPGSILMPDYIIXXXXXXXXXXXXDGLDEDDGNKHHILT-EFYIGGRESFITDGSSAARDDLVXXXXXXXXXXXXXXXXXFIFHE--AGIRNILIS-IIAQI---HLKDRLAVQRFVASMILAYWDPDHLLAMRNLNDCSL--SPLQSQLLTALEEPIYYQEILSQFKQMHKACRDLILIYIEREIPL 2344
            SRLD+LF LL++    + R AAA Q+G++   +   +  LLAK+L Y +   W  RIAA  AV  I  N   W P            S   + S+ ++  + ++  +LK G  L      +F +L E  T +   ++ LAR        LG             L  DE                     C   N +T++  EL++S+    MS  +    K M     K   R   P+E+  D                 +++P  + K +     +T    E ++EWP   FCEEL  +L++  WE+RHGA T LRE+++  G+         S+  + +  H+ + E++V+RLLC   LD+  DFVSDE+VAPVRE+CAQ LGV   H+    V +  N LL LL  D+W V HG LLG+KY LA R DL+ VLLP +   I+  L+ + DDDVR  A AAL+P+        V +   E+ ++   LWD L    D T S  T +++ LL  L     + Y Q     M     ++L   + R+ W +  ++   VR AA+ T   +L    QS  + +  I     I  +L  + Q  +++ + ++      VW + +   P+Q +   SC  +  W+C  MQ + +      +L            A +    G     GN     T + YI G E+   D     RD +V+RARL + +LL  LC+     +  A  + I  +  +AQ+   HL  + A+QR   +++L  W      A++   DC +  S +Q +LL  L E +YY EI   F +M   C+ LI +  +  I L
Sbjct:    4 SRLDRLFILLDTGTTPVTRKAAAQQLGEVVKLHPHELHNLLAKVLTYLRSPNWDTRIAAGQAVEAIVKNIPEWNPSPKPKEESCEDLSPEDSSSDRLSFYHFDISRLLKHGASLLGSAGAEF-ELQEDKTGEMDPKERLARQRKLLQKKLGLDMGAAIGMDTEELFNDEDLDDTCQSSVVKAHGVKVTAGCSSHNHLTIQAAELIDSEFRTGMSSRQKNKAKRMAKLVAKQRSRDVDPNEKSNDSFEGEPEEKRRKTTNVVIDQPAAQPKVLIDNVPDTSSVLEESSEWPLESFCEELCNDLFNPSWEVRHGAGTGLREILKCHGAA--GGKLVGSTAQQMSRQHQEWIEDLVIRLLCVFALDRFGDFVSDEVVAPVRETCAQTLGVALRHMNESGVFMTVNVLLKLLREDQWEVRHGGLLGIKYALAVRQDLMGVLLPRVLPAITEGLQ-DLDDDVRAVAAAALIPVV----DGLVQLQTNEVPSIVNTLWDALLDLDDLTAS--TNSIMTLLSSL-----LTYPQVRLCSMQ----QSLTVLVPRV-WPFLRHTISSVRRAALETLYTLLSTADQSCAVWINPI-----IQDMLRHIFQSCILESHEEILELIQKVWMELLFQAPQQYVVAASCPWMGAWLCLMMQASHIPIDQNMLL---------EVKARSKDKAGAKARLGNSQAKETVQEYIAGAETVADD--PLTRDYVVVRARLMSAKLLGALCKCICDPQLNAATQEIRPAESLAQLLLFHLNSKSALQRIAVALVLCEW-----AALQ--KDCQVVSSMVQPRLLAILAEQLYYDEIAIPFTRMQNECKQLITLLADANIDL 802          

Query: 3374 GAIELIYLVCHS---GLLPYRLAIAVIILPVVLACLNAPFDPLRRVATHVFSXXXXXXXXESSGADLSILTPARQQQRKQHLSFLDSLLNPKLIGQYNAHHSV-VSAKLRQYQEEGVNWLGFLNRYGLHGVLADDMGLGKTLQAICVIAGEY---------SRAPSTCP-PSLIVCPPTLTVHWHQEFKKFLVNLPDFNTIVYLGTPMYRQCIFNSLSRYQVVITSYDTLRSDMNLLARPTFPRCGTDVTKGSLMANSNVWNYVVLDEGHLIRNYKSKVAVATRALCARHRLVLTGTPIQNRVGELWSLFDFLMPGLLGTCTEFNRRYGRVLEQNGSNSGRKVDSEAGTLALELLHRQVLPFMLRRVKDDVLQELPPKIMQDYMCTMSPLQLRLYTHCMESQA-ATDTDFVELVD-KSYKENSAINQHRHGFQTMHYLRLVCNHPSLGLTSSHPLYRTLMRELAANNQCLDDINLSGKLVALRQLILDCGVGVSGAGEEELDETSVVASNRLLVFCQSIKMMELVD-KMIRNEIPKATHLRLDGSVPAKDRQQIVEKFSCDAXXXXXXXXXXXXXXXXXXXXANIVIFVEHDWNPMRDLQAMDRAHRIGQKH 5158
            GAIE +  V       ++PY   I ++++PV L  ++ P D +R +AT  F+ L+ LLPLE+   D   ++    +Q+ +   FL+ LL+ + +  Y  H  V + A+LR+YQ++GVNWL FLN+Y LHG+L DDMGLGKTLQ+IC++AG++         ++A    P PSL+VCPPTLT HW  E  KF       + + Y G P  R  + + + ++ +++ SYD +R+D++      F                   NY +LDEGH+I+N K+K++ A + L A  RL+L+GTPIQN V ELWSLFDFLMPG LGT  +F  RYG+ +  +        + EAG LA+E LHRQVLPF+LRR+K+DVLQ+LPPKI+QDY C +SPLQ++LY    +S+A A+  D +     +  +E   +    H FQ + YLR +CNHPSL LT  HP Y+ +  +LAA N  L DI  + KL AL+QL+LDCG+G  G  E   +  +VVA +R+L+FCQ   M+++V+  +++ ++P  T+LRLDGSVPA  R  IV +F+ D SID+LLLTT +GGLGLNLT A+ V+FVEHDWNPMRDLQAMDRAHRIGQ+ 
Sbjct: 1165 GAIEALACVMEQLEVDIIPY---IVLLVVPV-LGRMSDPSDSIRFMATQCFATLIRLLPLEAGIPDPPAMSADLIRQKARERYFLEQLLDGRKLENY--HIPVPIKAELRKYQQDGVNWLSFLNKYKLHGILCDDMGLGKTLQSICILAGDHYLRAQEYAKTKAADCSPLPSLVVCPPTLTGHWVDEVGKFCTK-EYLHPLHYTGPPSERMRLQHQVKKHNLIVASYDVVRNDIDFFRNIKF-------------------NYCILDEGHIIKNGKTKLSKAIKQLAANFRLILSGTPIQNNVLELWSLFDFLMPGFLGTERQFAARYGKPILASRDAKSSSREQEAGVLAMEALHRQVLPFLLRRMKEDVLQDLPPKIIQDYYCNLSPLQVQLYEDFAKSRAKASVEDSISTASAEEEEEKPKLKATGHVFQALQYLRKLCNHPSLVLTPQHPEYKRVTDQLAAQNSGLRDIQHAPKLSALKQLLLDCGLGDGGGSETGTE--AVVAQHRVLIFCQLKSMLDIVEHDLLKPKMPTVTYLRLDGSVPAGLRHAIVSRFNNDPSIDVLLLTTHVGGLGLNLTGADTVVFVEHDWNPMRDLQAMDRAHRIGQEE 1748          

Query:   86 SRLDKLFELLESNHQNI-RNAAAIQIGQLSANNQVNISALLAKLLPYAKHKIWVVRIAASDAVRHIGNNAKLWVPGTSE--------SNVTNVSNLINLENLNLHDILKIGTRLYSR---DFKDLDEANTNQNINRDELARH-------LGF------------LIPDE---------------------CEIKNLITVKDCELVESKSENKMSV-ELAVMKSMENSPKKPVKR---PHEEVQD-----------------VNEPGTKMKCVEKIGNETER--ERNTEWPWVDFCEELLKNLWDAKWEIRHGAATCLRELIRSQGSIMLPKNANISSTDKFAACHERFQEEIVVRLLCTLTLDQLSDFVSDEMVAPVRESCAQALGVISVHLTRRLVEILANQLLSLLNHDEWRVNHXXXXXXXXXXXXRMDLVEVLLPIIYDPISSHLKGNXXXXXXXXXXXXLMPLFGDCCSNTVAISNEELDTLKTDLWDVLAVRIDCTTSGATCAVLQLLERLYEKCNVVYNQSEDQPMATDRVKALNEYINRLHWCYFNYS-DLVRLAAVRTCRAVL----QSIGIKVGTILEHGTIXXXXXXXXXXXXIDDNCQVAAEAHSVWNQFIDSLPEQLLARVSCERLEIWMCSAMQPARLSYTPGSILMPDYIIXXXXXXXXXXXXDGLDEDDGNKHHILT-EFYIGGRESFITDGSSAARDDLVXXXXXXXXXXXXXXXXXFIFHE--AGIRNILIS-IIAQI---HLKDRLAVQRFVASMILAYWDPDHLLAMRNLNDCSL--SPLQSQLLTALEEPIYYQEILSQFKQMHKACRDLILIYIEREIPL 2344
            SRLD+LF LL++    + R AAA Q+G++   +   +  LLAK+L Y +   W  RIAA  AV  I  N   W P            S   + S+ ++  + ++  +LK G  L      +F +L E  T +   ++ LAR        LG             L  DE                     C   N +T++  EL++S+    MS  +    K M     K   R   P+E+  D                 +++P  + K +     +T    E ++EWP   FCEEL  +L++  WE+RHGA T LRE+++  G+         S+  + +  H+ + E++V+RLLC   LD+  DFVSDE+VAPVRE+CAQ LGV   H+    V +  N LL LL  D+W V HG LLG+KY LA R DL+ VLLP +   I+  L+ + DDDVR  A AAL+P+        V +   E+ ++   LWD L    D T S  T +++ LL  L     + Y Q     M     ++L   + R+ W +  ++   VR AA+ T   +L    QS  + +  I     I  +L  + Q  +++ + ++      VW + +   P+Q +   SC  +  W+C  MQ + +      +L            A +    G     GN     T + YI G E+   D     RD +V+RARL + +LL  LC+     +  A  + I  +  +AQ+   HL  + A+QR   +++L  W      A++   DC +  S +Q +LL  L E +YY EI   F +M   C+ LI +  +  I L
Sbjct:    4 SRLDRLFILLDTGTTPVTRKAAAQQLGEVVKLHPHELHNLLAKVLTYLRSPNWDTRIAAGQAVEAIVKNIPEWNPSPKPKEESCEDLSPEDSSSDRLSFYHFDISRLLKHGASLLGSAGAEF-ELQEDKTGEMDPKERLARQRKLLQKKLGLDMGAAIGMDTEELFNDEDLDDTCQSSVVKAHGVKVTAGCSSHNHLTIQAAELIDSEFRTGMSSRQKNKAKRMAKLVAKQRSRDVDPNEKSNDSFEGEPEEKRRKTTNVVIDQPAAQPKVLIDNVPDTSSVLEESSEWPLESFCEELCNDLFNPSWEVRHGAGTGLREILKCHGAA--GGKLVGSTAQQMSRQHQEWIEDLVIRLLCVFALDRFGDFVSDEVVAPVRETCAQTLGVALRHMNESGVFMTVNVLLKLLREDQWEVRHGGLLGIKYALAVRQDLMGVLLPRVLPAITEGLQ-DLDDDVRAVAAAALIPVV----DGLVQLQTNEVPSIVNTLWDALLDLDDLTAS--TNSIMTLLSSL-----LTYPQVRLCSMQ----QSLTVLVPRV-WPFLRHTISSVRRAALETLYTLLSTADQSCAVWINPI-----IQDMLRHIFQSCILESHEEILELIQKVWMELLFQAPQQYVVAASCPWMGAWLCLMMQASHIPIDQNMLL---------EVKARSKDKAGAKARLGNSQAKETVQEYIAGAETVADD--PLTRDYVVVRARLMSAKLLGALCKCICDPQLNAATQEIRPAESLAQLLLFHLNSKSALQRIAVALVLCEW-----AALQ--KDCQVVSSMVQPRLLAILAEQLYYDEIAIPFTRMQNECKQLITLLADANIDL 802          

Query: 3683 KLRQYQEEGVNWLGFLNRYGLHGVLADDMGLGKTLQAICVIAG-EYSRAPSTCP--------PSLIVCPPTLTVHWHQEFKKFLVNLPDFNTIVYLGTPMY----RQCIFNSLSRYQVVITSYDTLRSDMNLLARPTFPRCGTDVTKGSLMANSNVWNYVVLDEGHLIRNYKSKVAVATRALCARHRLVLTGTPIQNRVGELWSLFDFLMPGLLGTCTEFNRRYGRVLEQNGSNSGRKVDSEAGTLALELLHRQVLPFMLRRVKDDVLQ--ELPPKIMQDYMCTMSPLQLRLYTHCMESQAATDTDFVELVDKSYKENSAINQHRHGFQTMHYLRLVCNHPSLGLTSSHPLYRTLMRELAANNQCLDDINLSGKLVALRQLILDCGVGVSGAGEEELDETSVVASNRLLVFCQSIKMMELVDKMIRNEIPKATHLRLDGSVPAKDRQQIVEKFSCDAXXXXXXXXXXXXXXXXXXXXANIVIFVEHDWNPMRDLQAMDRAHRIGQKHTVIVYRLITAQSIEEKIMNLQEFKKFLANAVVSKDNNQMASMNTENILEIMNKEANWPTQSPPASANGKQKVVSSVSGGTETQLGSKSVLSKIS 5440
            KL +YQ+ GV W+  L+     G+L D+MGLGKT+Q I  +AG  YS+  +           P++IVCP T+   W +EF  +    P F   V   T  +     + I    S + ++ITSY  +R+  ++L R                     W+Y++LDEGH IRN  + V  A +     HR +L+G+P+QN + ELWSLFDF+ PG LGT   F  ++   +   G ++   V  +       +L   + P++LRR+K DV     LP K  Q   C ++  Q ++Y   ++S+                    +N     F  +  LR +CNHP L  +    + + +  +     +       SGKL+ +  L+                       +R+L+F QS +M+++++  +R      ++L++DG+     RQ ++ +++ D SI I LLTT +GGLG+NLT AN VI  + DWNP  D QA +RA RIGQ   V +YRL+TA +IEEKI + Q FK+FL N V+ KD  Q     + +I E+        T + P  + G +        G++ ++  K    K++
Sbjct:  497 KLYKYQQTGVRWMWELHCQQAGGILGDEMGLGKTIQVISFLAGLSYSKLRTRGSNYRYAGLGPTVIVCPATVMHQWVKEFHTWW---PPFRVAVLHETGSFTSKKEKLIPEIASCHGILITSYSAVRNLQDILIRYD-------------------WHYIILDEGHKIRNPNAAVTAACKQFQTPHRFILSGSPMQNNLKELWSLFDFVFPGKLGTLPVFMEQFSVPITMGGYSNASPVQVQTAYKCACVLRDTINPYLLRRMKADVKANLSLPDKNEQVLFCRLTEEQRQVYQSFLDSKEVYQI---------------LNGDMQVFSGLIALRKICNHPDL-FSGGPRMLKGIPEDQLTEEEHFGFWRRSGKLIVVESLL----------------RLWFKQGHRVLLFSQSRQMLDILEVFVREN--NYSYLKMDGTTTIASRQPLIARYNQDRSIFIFLLTTKVGGLGVNLTGANRVIIYDPDWNPSTDTQARERAWRIGQTLQVTIYRLLTAGTIEEKIYHRQIFKQFLTNRVL-KDPKQRRFFKSNDIYELF-------TLADPDGSQGTETSAIFAGTGSDVKVTKKPARPKLT 1033          

Query: 3683 KLRQYQEEGVNWLGFLNRYGLHGVLADDMGLGKTLQAICVIAG-EYSRAPSTCP--------PSLIVCPPTLTVHWHQEFKKFLVNLPDFNTIVYLGTPMY----RQCIFNSLSRYQVVITSYDTLRSDMNLLARPTFPRCGTDVTKGSLMANSNVWNYVVLDEGHLIRNYKSKVAVATRALCARHRLVLTGTPIQNRVGELWSLFDFLMPGLLGTCTEFNRRYGRVLEQNGSNSGRKVDSEAGTLALELLHRQVLPFMLRRVKDDVLQ--ELPPKIMQDYMCTMSPLQLRLYTHCMESQAATDTDFVELVDKSYKENSAINQHRHGFQTMHYLRLVCNHPSLGLTSSHPLYRTLMRELAANNQCLDDINLSGKLVALRQLILDCGVGVSGAGEEELDETSVVASNRLLVFCQSIKMMELVDKMIRNEIPKATHLRLDGSVPAKDRQQIVEKFSCDAXXXXXXXXXXXXXXXXXXXXANIVIFVEHDWNPMRDLQAMDRAHRIGQKHTVIVYRLITAQSIEEKIMNLQEFKKFLANAVVSKDNNQMASMNTENILEIMNKEANWPTQSPPASANGKQKVVSSVSGGTETQLGSKSVLSKIS 5440
            KL +YQ+ GV W+  L+     G+L D+MGLGKT+Q I  +AG  YS+  +           P++IVCP T+   W +EF  +    P F   V   T  +     + I    S + ++ITSY  +R+  ++L R                     W+Y++LDEGH IRN  + V  A +     HR +L+G+P+QN + ELWSLFDF+ PG LGT   F  ++   +   G ++   V  +       +L   + P++LRR+K DV     LP K  Q   C ++  Q ++Y   ++S+                    +N     F  +  LR +CNHP L  +    + + +  +     +       SGKL+ +  L+                       +R+L+F QS +M+++++  +R      ++L++DG+     RQ ++ +++ D SI I LLTT +GGLG+NLT AN VI  + DWNP  D QA +RA RIGQ   V +YRL+TA +IEEKI + Q FK+FL N V+ KD  Q     + +I E+        T + P  + G +        G++ ++  K    K++
Sbjct:  497 KLYKYQQTGVRWMWELHCQQAGGILGDEMGLGKTIQVISFLAGLSYSKLRTRGSNYRYAGLGPTVIVCPATVMHQWVKEFHTWW---PPFRVAVLHETGSFTSKKEKLIPEIASCHGILITSYSAVRNLQDILIRYD-------------------WHYIILDEGHKIRNPNAAVTAACKQFQTPHRFILSGSPMQNNLKELWSLFDFVFPGKLGTLPVFMEQFSVPITMGGYSNASPVQVQTAYKCACVLRDTINPYLLRRMKADVKANLSLPDKNEQVLFCRLTEEQRQVYQSFLDSKEVYQI---------------LNGDMQVFSGLIALRKICNHPDL-FSGGPRMLKGIPEDQLTEEEHFGFWRRSGKLIVVESLL----------------RLWFKQGHRVLLFSQSRQMLDILEVFVREN--NYSYLKMDGTTTIASRQPLIARYNQDRSIFIFLLTTKVGGLGVNLTGANRVIIYDPDWNPSTDTQARERAWRIGQTLQVTIYRLLTAGTIEEKIYHRQIFKQFLTNRVL-KDPKQRRFFKSNDIYELF-------TLADPDGSQGTETSAIFAGTGSDVKVTKKPARPKLT 1033          

Query:   80 MASRLDKLFELLESNHQNIRNAAAIQIGQLSANNQVNISALLAKLLPYAKHKIWVVRIAASDAVRHIGNNAKLWVPGTSESNVTNVSNLINLENLNLHDILKIGTRLYSRDFKDLDEANTNQNINRDELARHLGFLIPDECEIKNLITVKDCELVESKSENKMSVELAVMKSMENSPKKPVKRPHEEVQDVNEPGTKMKCVEKIGNETERERNTEWPWVDFCEELLKNLWDAKWEIRHGAATCLRELIRSQGSIMLPKNANISSTDKFAACHERFQEEIVVRLLCTLTLDQLSDFVSDEMVAPVRESCAQALGVISVHLTRRLVEILANQLLSLLNHDEWRVNHXXXXXXXXXXXXRMDLVEVLLPIIYDPISSHLKGNXXXXXXXXXXXXLMPLFGDCCSNTVAISNEELDTLKTDLWDVLAVRIDCTTSGATCAVLQLLERLYEKCNVVYNQSEDQPMATDRVKALNEYINRLHWCYFNYSDLVRLAAVRTCRAVLQSIGIKVGTILEHGTIXXXXXXXXXXXXIDDNCQVAAEAHSVWNQFIDSLPEQLLARVSCERLEIWMCSAMQPARLSYTPGSILMPDYIIXXXXXXXXXXXXDGLDEDDGNKHHILTEFYIGGRESFITDGSSAARDDLVXXXXXXXXXXXXXXXXXFIFHEAGIRNILISIIAQIHLKDRLAVQRFVASMILAYWDPDHLLAMRNLNDCSLSPLQSQLLTALEEPIYYQEILSQFKQMHKACRDLILIYIEREIPLPPSIMNAVGPNASPVSIALNISQCQSLISSEMCSLCPPESMTTFSCATAAVDTCAQQHATLCRLVDIAVGRALLQWGWXXXXXXXXXXXXXSAVRSETCVTLQTEACIALAQLVVDHNSQTRLLAPVTKLVKNLIQYQSEAIDSLATMQPHEVEQGEIVAIYKTSQLGREAFPRQEDNGTAVAIDNDVMIKLRGSRLALEKIYSRFVSSSESDLDHSFLMEIIYH 3019
            MASRLDKLFELLESNHQNIRNAAAIQIGQLSANNQVNISALLAKLLPYAKHKIWVVRIAASDAVRHIGNNAKLWVPGTSESNVTNVSNLINLENLNLHDILKIGTRLYSRDFKDLDEANTNQNINRDELARHLGFLIPDECEIKNLITVKDCELVESKSENKMSVELAVMKSMENSPKKPVKRPHEEVQDVNEPGTKMKCVEKIGNETERERNTEWPWVDFCEELLKNLWDAKWEIRHGAATCLRELIRSQGSIMLPKNANISSTDKFAACHERFQEEIVVRLLCTLTLDQLSDFVSDEMVAPVRESCAQALGVISVHLTRRLVEILANQLLSLLNHDEWRVNHGALLGLKYLLAARMDLVEVLLPIIYDPISSHLKGNCDDDVRCAAVAALMPLFGDCCSNTVAISNEELDTLKTDLWDVLAVRIDCTTSGATCAVLQLLERLYEKCNVVYNQSEDQPMATDRVKALNEYINRLHWCYFNYSDLVRLAAVRTCRAVLQSIGIKVGTILEHGTILQVLSQLVQRVLIDDNCQVAAEAHSVWNQFIDSLPEQLLARVSCERLEIWMCSAMQPARLSYTPGSILMPDYIITTAAGAAATVVGDGLDEDDGNKHHILTEFYIGGRESFITDGSSAARDDLVLRARLAACQLLARLCQRFIFHEAGIRNILISIIAQIHLKDRLAVQRFVASMILAYWDPDHLLAMRNLNDCSLSPLQSQLLTALEEPIYYQEILSQFKQMHKACRDLILIYIEREIPLPPSIMNAVGPNASPVSIALNISQCQSLISSEMCSLCPPESMTTFSCATAAVDTCAQQHATLCRLVDIAVGRALLQWGWLPLKLTPLIKPLISAVRSETCVTLQTEACIALAQLVVDHNSQTRLLAPVTKLVKNLIQYQSEAIDSLATMQPHEVEQGEIVAIYKTSQLGREAFPRQEDNGTAVAIDNDVMIKLRGSRLALEKIYSRFVSSSESDLDHSFLMEIIYH
Sbjct:    1 MASRLDKLFELLESNHQNIRNAAAIQIGQLSANNQVNISALLAKLLPYAKHKIWVVRIAASDAVRHIGNNAKLWVPGTSESNVTNVSNLINLENLNLHDILKIGTRLYSRDFKDLDEANTNQNINRDELARHLGFLIPDECEIKNLITVKDCELVESKSENKMSVELAVMKSMENSPKKPVKRPHEEVQDVNEPGTKMKCVEKIGNETERERNTEWPWVDFCEELLKNLWDAKWEIRHGAATCLRELIRSQGSIMLPKNANISSTDKFAACHERFQEEIVVRLLCTLTLDQLSDFVSDEMVAPVRESCAQALGVISVHLTRRLVEILANQLLSLLNHDEWRVNHGALLGLKYLLAARMDLVEVLLPIIYDPISSHLKGNCDDDVRCAAVAALMPLFGDCCSNTVAISNEELDTLKTDLWDVLAVRIDCTTSGATCAVLQLLERLYEKCNVVYNQSEDQPMATDRVKALNEYINRLHWCYFNYSDLVRLAAVRTCRAVLQSIGIKVGTILEHGTILQVLSQLVQRVLIDDNCQVAAEAHSVWNQFIDSLPEQLLARVSCERLEIWMCSAMQPARLSYTPGSILMPDYIITTAAGAAATVVGDGLDEDDGNKHHILTEFYIGGRESFITDGSSAARDDLVLRARLAACQLLARLCQRFIFHEAGIRNILISIIAQIHLKDRLAVQRFVASMILAYWDPDHLLAMRNLNDCSLSPLQSQLLTALEEPIYYQEILSQFKQMHKACRDLILIYIEREIPLPPSIMNAVGPNASPVSIALNISQCQSLISSEMCSLCPPESMTTFSCATAAVDTCAQQHATLCRLVDIAVGRALLQWGWLPLKLTPLIKPLISAVRSETCVTLQTEACIALAQLVVDHNSQTRLLAPVTKLVKNLIQYQSEAIDSLATMQPHEVEQGEIVAIYKTSQLGREAFPRQEDNGTAVAIDNDVMIKLRGSRLALEKIYSRFVSSSESDLDHSFLMEIIYH 980          

Query: 3767 MGLGKTLQAICVIAGEYSRAPSTCPPSLIVCPPTLTVHWHQEFKKFLVNLPDFNTIVYLGTPMYRQCIFNSLSRYQVVITSYDTLRSDMNLLARPTFPRCGTDVTKGSLMANSNVWNYVVLDEGHLIRNYKSKVAVATRALCARHRLVLTGTPIQNRVGELWSLFDFLMPGLLGTCTEFNRRYGRVLEQNGSNSGRKVDSEAGTLALELLHRQVLPFMLRRVKDDVLQELPPKIMQDYMCTMSPLQLRLYTHCMESQAATDTDFVELVDKSYKENSAINQHRHGFQTMHYLRLVCNHPSLGLTSSHPLYRTLMRELAANNQCLDDINLSGKLVALRQLILDCGVGVSGAGEEELDETSVVASNRLLVFCQSIKMMELVDKMIRNEIPKATHLRLDGSVPAKDRQQIVEKFSCDAXXXXXXXXXXXXXXXXXXXXANIVIFVEHDWNPMRDLQAMDRAHRIGQKHTVIVYRLITAQSIEEKIMNLQEFKKFLANAVVSKDNNQMASMNTENILEIMNKEANWPTQSPPASANGKQKVVSSVSGGTETQLGSKSVLSKISKADSGERVYDCLDEYDQEYNLDSFV 5515
            MGLGKTLQAICVIAGEYSRAPSTCPPSLIVCPPTLTVHWHQEFKKFLVNLPDFNTIVYLGTPMYRQCIFNSLSRYQVVITSYDTLRSDMNLLARPTFPRCGTDVTKGSLMANSNVWNYVVLDEGHLIRNYKSKVAVATRALCARHRLVLTGTPIQNRVGELWSLFDFLMPGLLGTCTEFNRRYGRVLEQNGSNSGRKVDSEAGTLALELLHRQVLPFMLRRVKDDVLQELPPKIMQDYMC MSPLQLRLYTHCMESQAATDTDFVELVDKSYKENSAINQHRHGFQTMHYLRLVCNHPSLGLTSSHPLYRTLMRELAANNQCLDDINLSGKLVALRQLILDCGVGVSGAGEEELDETSVVASNRLLVFCQSIKMMELVDKMIRNEIPKATHLRLDGSVPAKDRQQIVEKFSCDASIDILLLTTSIGGLGLNLTSANIVIFVEHDWNPMRDLQAMDRAHRIGQKHTVIVYRLITAQSIEEKIMNLQEFKKFLANAVVSKDNNQMASMNTENILEIMNKEANWPTQSPPASANGKQKVVSSVSGGTETQLGSKSVLSKI+KADSGERVYDC DEYDQEYNLDSFV
Sbjct:    1 MGLGKTLQAICVIAGEYSRAPSTCPPSLIVCPPTLTVHWHQEFKKFLVNLPDFNTIVYLGTPMYRQCIFNSLSRYQVVITSYDTLRSDMNLLARPTFPRCGTDVTKGSLMANSNVWNYVVLDEGHLIRNYKSKVAVATRALCARHRLVLTGTPIQNRVGELWSLFDFLMPGLLGTCTEFNRRYGRVLEQNGSNSGRKVDSEAGTLALELLHRQVLPFMLRRVKDDVLQELPPKIMQDYMCNMSPLQLRLYTHCMESQAATDTDFVELVDKSYKENSAINQHRHGFQTMHYLRLVCNHPSLGLTSSHPLYRTLMRELAANNQCLDDINLSGKLVALRQLILDCGVGVSGAGEEELDETSVVASNRLLVFCQSIKMMELVDKMIRNEIPKATHLRLDGSVPAKDRQQIVEKFSCDASIDILLLTTSIGGLGLNLTSANIVIFVEHDWNPMRDLQAMDRAHRIGQKHTVIVYRLITAQSIEEKIMNLQEFKKFLANAVVSKDNNQMASMNTENILEIMNKEANWPTQSPPASANGKQKVVSSVSGGTETQLGSKSVLSKINKADSGERVYDCFDEYDQEYNLDSFV 583          

Query: 3953 MYRQCIFNSLSRYQVVITSYDTLRSDMNLLARPTFPRCGTDVTKGSLMANSNVWNYVVLDEGHLIRNYKSKVAVATRALCARHRLVLTGTPIQNRVGELWSLFDFLMPGLLGTCTEFNRRYGRVLEQNGSNSGRKVDSEAGTLALELLHRQVLPFMLRRVKDDVLQELPPKIMQDYMCTMSPLQLRLYTHCMESQAATDTDFVELVDKSYKENSAINQHRHGFQTMHYLRLVCNHPSLGLTSSHPLYRTLMRELAANNQCLDDINLSGKLVALRQLILDCGVGVSGAGEEELDETSVVASNRLLVFCQSIKMMELVDKMIRNEIPKATHLRLDGSVPAKDRQQIVEKFSCDAXXXXXXXXXXXXXXXXXXXXANIVIFVEHDWNPMRDLQAMDRAHRIGQKHTVIVYRLITAQSIEEKIMNLQEFKKFLANAVVSKDNNQMASMNTENILEIMNKEANWPTQSPPASANGKQKVVSSVSGGTETQLGSKSVLSKISKADSGERVYDCLDEYDQEYNLDSFV 5515
            MYRQCIFNSLSRYQVVITSYDTLRSDMNLLARPTFPRCGTDVTKGSLMANSNVWNYVVLDEGHLIRNYKSKVAVATRALCARHRLVLTGTPIQNRVGELWSLFDFLMPGLLGTCTEFNRRYGRVLEQNGSNSGRKVDSEAGTLALELLHRQVLPFMLRRVKDDVLQELPPKIMQDYMC MSPLQLRLYTHCMESQAATDTDFVELVDKSYKENSAINQHRHGFQTMHYLRLVCNHPSLGLTSSHPLYRTLMRELAANNQCLDDINLSGKLVALRQLILDCGVGVSGAGEEELDETSVVASNRLLVFCQSIKMMELVDKMIRNEIPKATHLRLDGSVPAKDRQQIVEKFSCDASIDILLLTTSIGGLGLNLTSANIVIFVEHDWNPMRDLQAMDRAHRIGQKHTVIVYRLITAQSIEEKIMNLQEFKKFLANAVVSKDNNQMASMNTENILEIMNKEANWPTQSPPASANGKQKVVSSVSGGTETQLGSKSVLSKI+KADSGERVYDC DEYDQEYNLDSFV
Sbjct:    1 MYRQCIFNSLSRYQVVITSYDTLRSDMNLLARPTFPRCGTDVTKGSLMANSNVWNYVVLDEGHLIRNYKSKVAVATRALCARHRLVLTGTPIQNRVGELWSLFDFLMPGLLGTCTEFNRRYGRVLEQNGSNSGRKVDSEAGTLALELLHRQVLPFMLRRVKDDVLQELPPKIMQDYMCNMSPLQLRLYTHCMESQAATDTDFVELVDKSYKENSAINQHRHGFQTMHYLRLVCNHPSLGLTSSHPLYRTLMRELAANNQCLDDINLSGKLVALRQLILDCGVGVSGAGEEELDETSVVASNRLLVFCQSIKMMELVDKMIRNEIPKATHLRLDGSVPAKDRQQIVEKFSCDASIDILLLTTSIGGLGLNLTSANIVIFVEHDWNPMRDLQAMDRAHRIGQKHTVIVYRLITAQSIEEKIMNLQEFKKFLANAVVSKDNNQMASMNTENILEIMNKEANWPTQSPPASANGKQKVVSSVSGGTETQLGSKSVLSKINKADSGERVYDCFDEYDQEYNLDSFV 521          

Query: 3671 VVSAKLRQYQEEGVNWLGFLNRYGLHGVLADDMGLGKTLQAICVIAGEYSRAPSTCPPSLIVCPPTLTVHWHQEFKKFLVNLPDFNTIVYLGTPMYRQCIFNSL--SRYQVVITSYDTLRSDMNLLARPTFPRCGTDVTKGSLMANSNVWNYVVLDEGHLIRNYKSKVA-VATRALCARHRLVLTGTPIQNRVGELWSLFDFLMPGLLGTCTEFNRRYGRVLEQNGSNSGRKVD--SEAGTLALELLHRQVLPFMLRRVKDDVLQELPPKIMQDYMCTMSPLQLRLYTHCMESQAATDTDFVELVDKSYKENSAINQHRHGFQTMHYLRLVCNHPSLGLTSSHPLYRTLMRELAANNQCLDDINLSGKLVALRQLILDCGVGVSGAGEEELDE---TSVVASNRLLVFCQSIKMMELVDKMIRNEIPKATHLRLDGSVPAKDRQQIVEKFS-CDAXXXXXXXXXXXXXXXXXXXXANIVIFVEHDWNPMRDLQAMDRAHRIGQKHTVIVYRLITAQSIEEKIMNLQEFK 5230
            +++  L+QYQ +G+ WL  L    L+G+LAD+MGLGKT+Q I +I     R      P LI+ P +   +W  EF+K+    P    I+Y G+P  R+ +   L  S++ V++T+Y+ +  D + L++                     W Y+++DEGH ++N+  K+  +      A +RL+LTGTP+QN++ ELW+L +FL+P +  +   F + +        ++SG KV+   E   L +  LH+ + PF+LRR+K +V  +LP K+     C MS LQ ++Y++    +A      ++ VDK  K  +     R     +  LR +CNHP +         + +  ++   N   +        V + + I    +  +    E LD        A +R+L+FCQ   +M+L++  +     K  +LRLDG+  ++DR  ++  F+  ++   I +L+T  GGLGLNL SA+ VI  + DWNP +DLQA DRAHRIGQ++ V V RLI   SIEEKI+    FK
Sbjct:  543 LINGTLKQYQLKGLEWLVSLYNNNLNGILADEMGLGKTIQTIGLITYLMERK-KVNGPFLIIVPLSTMSNWAMEFEKW---GPSVKKILYKGSPKIRKELQAQLKTSKFNVLLTTYEYIIKDKSSLSKVK-------------------WKYMIIDEGHRMKNHHCKLTQILNTFYIAPYRLLLTGTPLQNKLPELWALLNFLLPNIFKSVNTFEQWFNAPF----ASSGEKVELNQEETLLIIRRLHKVLRPFLLRRLKKEVENQLPEKVEYVIKCEMSALQRKVYSNIQSKRA-----ILKSVDKDKKGRT----ERLWSNVLMQLRKICNHPYMFPEVEIEYAKHVFMKMHNGNPPPN--------VPIPKEIHGADLYRASGKFELLDRILPKLKRAKHRVLMFCQMTHLMDLMEPYLEYRCFK--YLRLDGTTKSEDRGDLLCAFNKPNSEFFIFMLSTRAGGLGLNLQSADTVIIFDSDWNPHQDLQAQDRAHRIGQQNEVRVLRLIMINSIEEKILAAARFK 1025          

Query: 3668 SVVSAKLRQYQEEGVNWLGFLNRYGLHGVLADDMGLGKTLQAICVIAGEYSRAPS---TCPPSLIVCPPTLTVHWHQEFKKFLVNLPDFNTIVYLGTPM---YRQCIFNSLSRY-QVVITSYDTLRSDMNLLARPTFPRCGTDVTKGSLMANSNVWNYVVLDEGHLIRNYKSKVAVATRALCARHRLVLTGTPIQNRVGELWSLFDFLMPGLLGTCTEFNRRYGRVLEQNGSNSGRKVDSEAGTLALELLHRQVLPFMLRRVKDDVLQELPPKIMQDYMCTMSPLQLRLYTHCMESQAATDTDFVELVDKSYKENSAINQHRHGFQTMHYLRLVCNHPSLGLTS-----SHPLYRTLMRELAANNQC--LDDINLSGKLVALRQLILDCGVGVSGAGEEELDETSVVASNRLLVFCQSIKMMELVDKMIRNEIPKATHLRLDGSVPAKDRQQIVEKF--SCDAXXXXXXXXXXXXXXXXXXXXANIVIFVEHDWNPMRDLQAMDRAHRIGQKHTVIVYRLITAQSIEEKIMNLQEFKKFLANAVVSKDNNQMASMNTENILEIM 5311
            S +  KL  YQ+ GV WL  L+  G  G+L D+MGLGKT+Q I  +AG  SR+        P LIVCP T+   W  EF+ +    P F   +   T       + +  S++ +  V+IT+Y ++     +L  P   R                W Y++LDEGH I+N  +KV    +    RHRL+++G+PIQN + ELWSL DF+ PG LG+   F + +   + + G      +  E       ++   +  ++LRR K +V  +LP K  Q   C ++  Q  +Y   + S+                    I   +  F  +  LR +CNHP L          HP+     RE   +         + SGK+V +++L+     G                 +++L+F Q   M++++ + I  E    +   +DG+     R  IV+KF  S      I LLTT +GGLGLNL  A+ V+  + DWNP  DLQA +RA RIGQ   V++YRL+ + S+EEKI + Q FK+FL N ++ K+  Q     T+++ ++ 
Sbjct:  275 SSIWNKLYGYQQAGVRWLLQLHDNGAGGILGDEMGLGKTIQVIAFLAG-LSRSKGGNYDIGPVLIVCPATVMRQWMDEFRAWA---PLFRVALLHATGSGYDKPERLLESIAHHPGVLITTYSSM-----VLHHPLLTRYD--------------WQYIILDEGHKIKNPNAKVTHCCKQFETRHRLIMSGSPIQNNLKELWSLVDFIYPGKLGSLASFIQNFAVPIMKGGYEHASPLQVETAYRCACVVRDTINEYLLRRTKAEVELQLPRKTEQVLFCGLTGHQNEVYREYLASRQC---------------KQIIAGQQVPFPGLVMLRKICNHPDLVTGGPKCVLDHPIL-GFAREATDDGHSYKFGHFSRSGKMVVVKELLRLWYRG----------------KHKVLLFTQGRMMLQILKRFI--EQQGYSMCTMDGTTAIGSRHAIVDKFNDSPYKEAFIFLLTTRVGGLGLNLVGADRVLVFDPDWNPCTDLQARERAWRIGQNRKVVIYRLVISGSVEEKIYHRQVFKQFLTNRIL-KNPRQRRFFKTQDLRDLF 780