TTF-type domain-containing protein

Overview
NameTTF-type domain-containing protein
Smed IDSMED30028697
Length (bp)1998
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of TTF-type domain-containing protein (SMED30028697) t-SNE clustered cells

Violin plots show distribution of expression levels for TTF-type domain-containing protein (SMED30028697) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of TTF-type domain-containing protein (SMED30028697) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for TTF-type domain-containing protein (SMED30028697) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30028697

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 8

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
nervous systemSMED30028697h1SMcG0004194 dd_Smed_v4_11239_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30028697h1SMcG0004194 dd_Smed_v4_11239_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
neuronSMED30028697h1SMcG0004194 dd_Smed_v4_11239_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		whole organism asexual adult colorimetric in situ hybridization evidence
parenchymal cellSMED30028697h1SMcG0004194 dd_Smed_v4_11239_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
non-ciliated neuronSMED30028697h1SMcG0004194 dd_Smed_v4_11239_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cilated neuronSMED30028697h1SMcG0004194 dd_Smed_v4_11239_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
posterior sideSMED30028697h1SMcG0004194 dd_Smed_v4_11239_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
posterior muscle cellSMED30028697h1SMcG0004194 dd_Smed_v4_11239_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of TTF-type domain-containing protein vs. Ensembl Human
Match: ZMYM1 (zinc finger MYM-type containing 1 [Source:HGNC Symbol;Acc:HGNC:26253])

HSP 1 Score: 60.8474 bits (146), Expect = 2.295e-17
Identity = 25/82 (30.49%), Postives = 48/82 (58.54%), Query Frame = 3 
Query:  699 VIVSEHFVTFLELHDTTGENMTKIAIDKLQELCVNLDDMRRQGYDNGANMHGKYNGVQARIRQLNPRTFFIPCSAHFLSLVL 944
            +++ E F+ F++  + TG ++ +     LQ++ V++D +  Q YD+  N+  K+N + A  ++  PR  +I C AHFL L +
Sbjct:  673 ILIKERFLGFVDTEEMTGTHLHRTIKTYLQQIGVDMDKIHGQAYDSTTNLKIKFNKIAAEFKKEEPRALYIHCYAHFLDLSI 754

HSP 2 Score: 48.9062 bits (115), Expect = 2.295e-17
Identity = 49/196 (25.00%), Postives = 88/196 (44.90%), Query Frame = 2 
Query:   56 IKGTTKDVVFCICCKIFSPNKFSLS----SNDGCRDGKNLSVIIKQHETSNGHTTAYSNRRELQVRLKSGTTMDD--INQKIIQSKTQHWRKVIERTLIRTLGGQNLELRGTCEKLFEPNKENLLKFIE*LGNYDP------IMSKHI*GIITSKIHTT*LRKTTQNKIVELLANKIKDHVLTQLKQAKYYSIILD 607
            ++ + KDV FC  C++F    FS      +  G  + K      ++HE S  H  +    RE Q     G   DD  I+ K I+   ++ + +IE  L   LG Q L LRG  + +   NK N L+ +E +   D       +M+  +    +++I         Q+ I+E++  ++   ++ ++  +  +SII D
Sbjct:  467 LENSKKDVAFCYSCQLFCQKYFSCGRESFATHGTSNWKKTLEKFRKHEKSEMHLKSLEFWREYQ--FCDGAVSDDLSIHSKQIEGNKKYLKLIIENILF--LGKQCLPLRGNDQSVSSVNKGNFLELLE-MRAKDKGEETFRLMNSQVDFYNSTQI---------QSDIIEIIKTEMLQDIVNEINDSSAFSIICD 648
[Close]
BLAST of TTF-type domain-containing protein vs. Ensembl Human
Match: ZMYM1 (zinc finger MYM-type containing 1 [Source:HGNC Symbol;Acc:HGNC:26253])

HSP 1 Score: 60.8474 bits (146), Expect = 2.295e-17
Identity = 25/82 (30.49%), Postives = 48/82 (58.54%), Query Frame = 3 
Query:  699 VIVSEHFVTFLELHDTTGENMTKIAIDKLQELCVNLDDMRRQGYDNGANMHGKYNGVQARIRQLNPRTFFIPCSAHFLSLVL 944
            +++ E F+ F++  + TG ++ +     LQ++ V++D +  Q YD+  N+  K+N + A  ++  PR  +I C AHFL L +
Sbjct:  673 ILIKERFLGFVDTEEMTGTHLHRTIKTYLQQIGVDMDKIHGQAYDSTTNLKIKFNKIAAEFKKEEPRALYIHCYAHFLDLSI 754

HSP 2 Score: 48.9062 bits (115), Expect = 2.295e-17
Identity = 49/196 (25.00%), Postives = 88/196 (44.90%), Query Frame = 2 
Query:   56 IKGTTKDVVFCICCKIFSPNKFSLS----SNDGCRDGKNLSVIIKQHETSNGHTTAYSNRRELQVRLKSGTTMDD--INQKIIQSKTQHWRKVIERTLIRTLGGQNLELRGTCEKLFEPNKENLLKFIE*LGNYDP------IMSKHI*GIITSKIHTT*LRKTTQNKIVELLANKIKDHVLTQLKQAKYYSIILD 607
            ++ + KDV FC  C++F    FS      +  G  + K      ++HE S  H  +    RE Q     G   DD  I+ K I+   ++ + +IE  L   LG Q L LRG  + +   NK N L+ +E +   D       +M+  +    +++I         Q+ I+E++  ++   ++ ++  +  +SII D
Sbjct:  467 LENSKKDVAFCYSCQLFCQKYFSCGRESFATHGTSNWKKTLEKFRKHEKSEMHLKSLEFWREYQ--FCDGAVSDDLSIHSKQIEGNKKYLKLIIENILF--LGKQCLPLRGNDQSVSSVNKGNFLELLE-MRAKDKGEETFRLMNSQVDFYNSTQI---------QSDIIEIIKTEMLQDIVNEINDSSAFSIICD 648
[Close]
BLAST of TTF-type domain-containing protein vs. Ensembl Human
Match: ZMYM1 (zinc finger MYM-type containing 1 [Source:HGNC Symbol;Acc:HGNC:26253])

HSP 1 Score: 60.8474 bits (146), Expect = 2.295e-17
Identity = 25/82 (30.49%), Postives = 48/82 (58.54%), Query Frame = 3 
Query:  699 VIVSEHFVTFLELHDTTGENMTKIAIDKLQELCVNLDDMRRQGYDNGANMHGKYNGVQARIRQLNPRTFFIPCSAHFLSLVL 944
            +++ E F+ F++  + TG ++ +     LQ++ V++D +  Q YD+  N+  K+N + A  ++  PR  +I C AHFL L +
Sbjct:  673 ILIKERFLGFVDTEEMTGTHLHRTIKTYLQQIGVDMDKIHGQAYDSTTNLKIKFNKIAAEFKKEEPRALYIHCYAHFLDLSI 754

HSP 2 Score: 48.9062 bits (115), Expect = 2.295e-17
Identity = 49/196 (25.00%), Postives = 88/196 (44.90%), Query Frame = 2 
Query:   56 IKGTTKDVVFCICCKIFSPNKFSLS----SNDGCRDGKNLSVIIKQHETSNGHTTAYSNRRELQVRLKSGTTMDD--INQKIIQSKTQHWRKVIERTLIRTLGGQNLELRGTCEKLFEPNKENLLKFIE*LGNYDP------IMSKHI*GIITSKIHTT*LRKTTQNKIVELLANKIKDHVLTQLKQAKYYSIILD 607
            ++ + KDV FC  C++F    FS      +  G  + K      ++HE S  H  +    RE Q     G   DD  I+ K I+   ++ + +IE  L   LG Q L LRG  + +   NK N L+ +E +   D       +M+  +    +++I         Q+ I+E++  ++   ++ ++  +  +SII D
Sbjct:  467 LENSKKDVAFCYSCQLFCQKYFSCGRESFATHGTSNWKKTLEKFRKHEKSEMHLKSLEFWREYQ--FCDGAVSDDLSIHSKQIEGNKKYLKLIIENILF--LGKQCLPLRGNDQSVSSVNKGNFLELLE-MRAKDKGEETFRLMNSQVDFYNSTQI---------QSDIIEIIKTEMLQDIVNEINDSSAFSIICD 648
[Close]
BLAST of TTF-type domain-containing protein vs. Ensembl Human
Match: ZMYM1 (zinc finger MYM-type containing 1 [Source:HGNC Symbol;Acc:HGNC:26253])

HSP 1 Score: 60.8474 bits (146), Expect = 2.295e-17
Identity = 25/82 (30.49%), Postives = 48/82 (58.54%), Query Frame = 3 
Query:  699 VIVSEHFVTFLELHDTTGENMTKIAIDKLQELCVNLDDMRRQGYDNGANMHGKYNGVQARIRQLNPRTFFIPCSAHFLSLVL 944
            +++ E F+ F++  + TG ++ +     LQ++ V++D +  Q YD+  N+  K+N + A  ++  PR  +I C AHFL L +
Sbjct:  673 ILIKERFLGFVDTEEMTGTHLHRTIKTYLQQIGVDMDKIHGQAYDSTTNLKIKFNKIAAEFKKEEPRALYIHCYAHFLDLSI 754

HSP 2 Score: 48.9062 bits (115), Expect = 2.295e-17
Identity = 49/196 (25.00%), Postives = 88/196 (44.90%), Query Frame = 2 
Query:   56 IKGTTKDVVFCICCKIFSPNKFSLS----SNDGCRDGKNLSVIIKQHETSNGHTTAYSNRRELQVRLKSGTTMDD--INQKIIQSKTQHWRKVIERTLIRTLGGQNLELRGTCEKLFEPNKENLLKFIE*LGNYDP------IMSKHI*GIITSKIHTT*LRKTTQNKIVELLANKIKDHVLTQLKQAKYYSIILD 607
            ++ + KDV FC  C++F    FS      +  G  + K      ++HE S  H  +    RE Q     G   DD  I+ K I+   ++ + +IE  L   LG Q L LRG  + +   NK N L+ +E +   D       +M+  +    +++I         Q+ I+E++  ++   ++ ++  +  +SII D
Sbjct:  467 LENSKKDVAFCYSCQLFCQKYFSCGRESFATHGTSNWKKTLEKFRKHEKSEMHLKSLEFWREYQ--FCDGAVSDDLSIHSKQIEGNKKYLKLIIENILF--LGKQCLPLRGNDQSVSSVNKGNFLELLE-MRAKDKGEETFRLMNSQVDFYNSTQI---------QSDIIEIIKTEMLQDIVNEINDSSAFSIICD 648
[Close]
BLAST of TTF-type domain-containing protein vs. Ensembl Human
Match: ZMYM5 (zinc finger MYM-type containing 5 [Source:HGNC Symbol;Acc:HGNC:13029])

HSP 1 Score: 60.077 bits (144), Expect = 9.847e-9
Identity = 33/104 (31.73%), Postives = 56/104 (53.85%), Query Frame = 2 
Query:    2 GRKFSCFHFYSRMSNGDK------IKGTTKDVVFCICCKIFSPNKFSLSSNDGCRDGKNLSVIIKQHETSNGHTTAYSNRRELQVRLKSGTTMDDINQKIIQSK 295
            GRKFS  ++   + NG+K      +  T+KD VFC+ CK+F   K  L + +GC+D ++LS I+ +HE S  H        +L+  LK    +D    ++ +++
Sbjct:  556 GRKFSETYYTRILPNGEKTTRSWLLYSTSKDSVFCLYCKLFGEGKNQLKNENGCKDWQHLSHILSKHEESEMHVNNSVKYSKLKSDLKKNKAIDAAEHRLYENE 659
[Close]
BLAST of TTF-type domain-containing protein vs. Ensembl Zebrafish
Match: CR762475.1 (pep chromosome:GRCz11:4:55494751:55498830:1 gene:ENSDARG00000098243.2 transcript:ENSDART00000172605.2 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CR762475.1)

HSP 1 Score: 76.6406 bits (187), Expect = 2.633e-22
Identity = 37/93 (39.78%), Postives = 54/93 (58.06%), Query Frame = 3 
Query:  705 VSEHFVTFLELHDTTGENMTKIAIDKLQELCVNLDDMRRQGYDNGANMHGKYNGVQARIRQLNPRTFFIPCSAHFLSLVLNDAVNICIQTVAF 983
            V E F+    L  TTG+ +  + I  LQ+  ++L ++R QGYD  ANM G Y G+Q+RIR  N +  ++ C AH L+LVL ++    I  V F
Sbjct:  433 VKERFLQVCTLESTTGKELENVVISLLQDNGLDLKNIRGQGYDGAANMSGMYKGLQSRIRAHNEKALYVHCQAHCLNLVLVESAKSSIHFVTF 525

HSP 2 Score: 49.2914 bits (116), Expect = 2.633e-22
Identity = 48/198 (24.24%), Postives = 85/198 (42.93%), Query Frame = 2 
Query:   74 DVVFCICCKIF-SPNKF---SLSSNDGCRDGKNLSVIIKQHETSNGHTTA------YSNRRELQVRLKSGTTMDDINQKIIQSKTQHWRKVIERTLIRT---LGGQNLELRGTCEKLFEPNKENLLKFIE*LGNYDPIMSKHI*GI-----ITSKIHTT*LRKTTQNKIVELLANKIKDHVLTQLKQAKYYSIILDCT 613
            D ++C  C+IF    KF   +     G    ++ +  +K+H ++  H  +      YS +      L++     DI  K I+ + +   + I   LI     L  Q    RG  E     N+ N ++ ++ L  YD +M  H+  I        K   + L   +QN I+  L   I+  +  ++K+A+ +SI+LD T
Sbjct:  220 DAIYCFSCRIFLREEKFKNKTAWKTLGINTWRSATGKMKEHASTEAHMMSMVRWNIYSKKA-----LQTAFDTSDIQGKAIRERERQRNREILTRLIDISLYLARQGQAFRGDDESSSSANQGNFIELVKTLAQYDSVMKLHLDAIQEKQASMKKPQVSLLSNRSQNDIIMSLGTFIRSKIQNEIKEAQIFSILLDET 412
[Close]
BLAST of TTF-type domain-containing protein vs. Ensembl Xenopus
Match: ENSXETT00000043220.1 (pep primary_assembly:Xenopus_tropicalis_v9.1:7:36411169:36451375:1 gene:ENSXETG00000018966.1 transcript:ENSXETT00000043220.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 86.2705 bits (212), Expect = 9.344e-35
Identity = 40/94 (42.55%), Postives = 57/94 (60.64%), Query Frame = 3 
Query:  702 IVSEHFVTFLELHDTTGENMTKIAIDKLQELCVNLDDMRRQGYDNGANMHGKYNGVQARIRQLNPRTFFIPCSAHFLSLVLNDAVNICIQTVAF 983
            I  E F+ F+       EN+    +D L+E  +++ D R Q YDN +NM G Y+G+QARI+Q+NP   +IPCSAH L+LV   A   C + V+F
Sbjct:  276 IPKERFIKFIPNVGHKAENLFSAVMDTLKEYHIDILDCRGQSYDNASNMSGPYSGLQARIKQVNPLAVYIPCSAHSLNLVGTSAAESCREAVSF 369

HSP 2 Score: 82.0333 bits (201), Expect = 9.344e-35
Identity = 52/165 (31.52%), Postives = 88/165 (53.33%), Query Frame = 2 
Query:  131 SNDGCRDGKNLSVIIKQHETSNGHTTAYSNRRELQVRLKSGTTMDDINQKIIQSKTQHWRKVIER--TLIRTLGGQNLELRGTCEKLFEPNKENLLKFIE*LGNYDPIMSKHI*GI-ITSKIHTT*LRKTTQNKIVELLANKIKDHVLTQLKQAKYYSIILDCTP 616
            +++G  D KN SV + +HE S  H   Y     +Q R K    +D +  +    + ++WR V++R  T ++TL  + L  RGT EK       N L  +E +  +DP +++HI     T    T+ L KT   + ++++A+ + + ++ + KQAKYYSI +D TP
Sbjct:   95 AHEGYNDWKNASVRLNEHEESKFHKDCY---LRMQNRAKISGRIDQLFLEKQNQEMEYWRNVLKRVVTAVKTLSSRGLPFRGTDEKFGSLTNGNYLMLLEAIAEHDPFLAEHIKKYGNTGTGSTSYLSKTVCFEFIDIVASSVLEVIINEAKQAKYYSISVDSTP 256
[Close]
BLAST of TTF-type domain-containing protein vs. Ensembl Xenopus
Match: slc10a6 (solute carrier family 10 (sodium/bile acid cotransporter), member 6 [Source:Xenbase;Acc:XB-GENE-988401])

HSP 1 Score: 64.6994 bits (156), Expect = 2.776e-10
Identity = 29/84 (34.52%), Postives = 50/84 (59.52%), Query Frame = 3 
Query:  699 VIVSEHFVTFLELHDTTGENMTKIAIDKLQELCVNLDDMRRQGYDNGANMHGKYNGVQARIRQLNPRTFFIPCSAHFLSLVLND 950
            V + E F+ F  L      ++  + +++  +  +N+D +  QGYD  + M GK  GVQA+I++  PR  F+ C++H L+LV+ND
Sbjct:  230 VKIREEFLGFATLKAVDATSIANVIMEQCIKFGLNMDKLYGQGYDGCSTMAGKEGGVQAKIKEKYPRAIFVYCASHKLNLVVND 313
[Close]
BLAST of TTF-type domain-containing protein vs. Ensembl Xenopus
Match: tbx18 (T-box 18 [Source:Xenbase;Acc:XB-GENE-489907])

HSP 1 Score: 61.6178 bits (148), Expect = 2.981e-9
Identity = 28/84 (33.33%), Postives = 50/84 (59.52%), Query Frame = 3 
Query:  699 VIVSEHFVTFLELHDTTGENMTKIAIDKLQELCVNLDDMRRQGYDNGANMHGKYNGVQARIRQLNPRTFFIPCSAHFLSLVLND 950
            V + E F+ F  L      ++  + +++  +  +N+D +  QGYD  + M GK  GVQA+I++  PR  F+ C++H L+LV+N+
Sbjct:  180 VKIREEFLGFATLKAFDATSIANVIMEQCIKFGLNIDKLYGQGYDGCSTMAGKEGGVQAKIKEKYPRAIFVHCASHKLNLVVNN 263
[Close]
BLAST of TTF-type domain-containing protein vs. Ensembl Mouse
Match: Zmym1 (zinc finger, MYM domain containing 1 [Source:MGI Symbol;Acc:MGI:1915560])

HSP 1 Score: 50.447 bits (119), Expect = 2.155e-13
Identity = 26/82 (31.71%), Postives = 43/82 (52.44%), Query Frame = 3 
Query:  699 VIVSEHFVTFLELHDTTGENMTKIAIDKLQELCVNLDDMRRQGYDNGANMHGKYNGVQARIRQLNPRTFFIPCSAHFLSLVL 944
            V+V E F+ F+   + TG ++       LQ++ V+ + +  Q YD+  N   K N V A  ++  PR  ++ C AHFL L +
Sbjct:  514 VLVKERFLGFVTAEEVTGVHVHGRIKAYLQQVGVDFNKICGQAYDSATNFTVKLNEVVAEFKKEEPRALYVHCHAHFLELAV 595

HSP 2 Score: 45.0542 bits (105), Expect = 2.155e-13
Identity = 42/186 (22.58%), Postives = 83/186 (44.62%), Query Frame = 2 
Query:   74 DVVFCICCKIFSPNKFSLS----SNDGCRDGKNLSVIIKQHETSNGHTTAYSNRRELQVRLKSGTTMDDINQKIIQSKTQHWRKVIERTLIRTLGGQNLELRGTCEKLFEPNKENLLKFIE----*LGNYDPIMSKHI*GIITSKIHTT*LRKTTQNKIVELLANKIKDHVLTQLKQAKYYSIILD 607
            ++ FC  C +F   KFS      +  G  D + +    ++HE S+ H  +    R+ Q           +  K I+   ++ R +IE  L   LG Q L L+G  + +   NK + L+ +E      G    +MS H+    +S +         Q +I+E++ +++   +++++  +  +SII +
Sbjct:  315 NIAFCYSCYLFFQKKFSCRREAFATQGTADWEKMLGNFRKHEESDVHLKSLQFWRQYQFLDAIPCDNSSVYSKQIEGNKKYLRLIIENILF--LGKQCLLLKGNDQSVSPMNKGSFLELLELRARDRGEVFQLMSSHV-DFYSSTL--------VQEEIIEMIKDEMLQDIVSEINASSAFSIICE 489
[Close]
BLAST of TTF-type domain-containing protein vs. Ensembl Mouse
Match: Zmym1 (zinc finger, MYM domain containing 1 [Source:MGI Symbol;Acc:MGI:1915560])

HSP 1 Score: 50.447 bits (119), Expect = 2.155e-13
Identity = 26/82 (31.71%), Postives = 43/82 (52.44%), Query Frame = 3 
Query:  699 VIVSEHFVTFLELHDTTGENMTKIAIDKLQELCVNLDDMRRQGYDNGANMHGKYNGVQARIRQLNPRTFFIPCSAHFLSLVL 944
            V+V E F+ F+   + TG ++       LQ++ V+ + +  Q YD+  N   K N V A  ++  PR  ++ C AHFL L +
Sbjct:  514 VLVKERFLGFVTAEEVTGVHVHGRIKAYLQQVGVDFNKICGQAYDSATNFTVKLNEVVAEFKKEEPRALYVHCHAHFLELAV 595

HSP 2 Score: 45.0542 bits (105), Expect = 2.155e-13
Identity = 42/186 (22.58%), Postives = 83/186 (44.62%), Query Frame = 2 
Query:   74 DVVFCICCKIFSPNKFSLS----SNDGCRDGKNLSVIIKQHETSNGHTTAYSNRRELQVRLKSGTTMDDINQKIIQSKTQHWRKVIERTLIRTLGGQNLELRGTCEKLFEPNKENLLKFIE----*LGNYDPIMSKHI*GIITSKIHTT*LRKTTQNKIVELLANKIKDHVLTQLKQAKYYSIILD 607
            ++ FC  C +F   KFS      +  G  D + +    ++HE S+ H  +    R+ Q           +  K I+   ++ R +IE  L   LG Q L L+G  + +   NK + L+ +E      G    +MS H+    +S +         Q +I+E++ +++   +++++  +  +SII +
Sbjct:  315 NIAFCYSCYLFFQKKFSCRREAFATQGTADWEKMLGNFRKHEESDVHLKSLQFWRQYQFLDAIPCDNSSVYSKQIEGNKKYLRLIIENILF--LGKQCLLLKGNDQSVSPMNKGSFLELLELRARDRGEVFQLMSSHV-DFYSSTL--------VQEEIIEMIKDEMLQDIVSEINASSAFSIICE 489
[Close]
BLAST of TTF-type domain-containing protein vs. Ensembl Mouse
Match: Zmym1 (zinc finger, MYM domain containing 1 [Source:MGI Symbol;Acc:MGI:1915560])

HSP 1 Score: 50.8322 bits (120), Expect = 5.912e-11
Identity = 26/82 (31.71%), Postives = 43/82 (52.44%), Query Frame = 3 
Query:  699 VIVSEHFVTFLELHDTTGENMTKIAIDKLQELCVNLDDMRRQGYDNGANMHGKYNGVQARIRQLNPRTFFIPCSAHFLSLVL 944
            V+V E F+ F+   + TG ++       LQ++ V+ + +  Q YD+  N   K N V A  ++  PR  ++ C AHFL L +
Sbjct:  416 VLVKERFLGFVTAEEVTGVHVHGRIKAYLQQVGVDFNKICGQAYDSATNFTVKLNEVVAEFKKEEPRALYVHCHAHFLELAV 497

HSP 2 Score: 36.965 bits (84), Expect = 5.912e-11
Identity = 43/193 (22.28%), Postives = 87/193 (45.08%), Query Frame = 2 
Query:   44 NGDKIKGTTKDVVF-CICCKIFSPNKFSLSSNDGCRDGKNLSVIIKQHETSNGHTTAYSNRRELQVRLKSGTTMDDINQKIIQSKTQHWRKVIERTLIRTLGGQNLELRGTCEKLFEPNKENLLKFIE*L----GNYDPIMSKHI*GIITSKIHTT*LRKTTQNKIVELLANKIKDHVLTQLKQAKYYSIILD 607
            N D ++GT   +    I  K FS  + + ++  G  D + +    ++HE S+ H  +    R+ Q           +  K I+   ++ R +IE  L   LG Q L L+G  + +   NK + L+ +E      G    +MS H+    +S +         Q +I+E++ +++   +++++  +  +SII +
Sbjct:  211 NTDLLQGTLSSLPTDVIMSKKFSCRREAFATQ-GTADWEKMLGNFRKHEESDVHLKSLQFWRQYQFLDAIPCDNSSVYSKQIEGNKKYLRLIIENILF--LGKQCLLLKGNDQSVSPMNKGSFLELLELRARDRGEVFQLMSSHV-DFYSSTL--------VQEEIIEMIKDEMLQDIVSEINASSAFSIICE 391
[Close]
BLAST of TTF-type domain-containing protein vs. UniProt/SwissProt
Match: sp|Q5SVZ6|ZMYM1_HUMAN (Zinc finger MYM-type protein 1 OS=Homo sapiens OX=9606 GN=ZMYM1 PE=1 SV=1)

HSP 1 Score: 60.8474 bits (146), Expect = 1.008e-16
Identity = 25/82 (30.49%), Postives = 48/82 (58.54%), Query Frame = 3 
Query:  699 VIVSEHFVTFLELHDTTGENMTKIAIDKLQELCVNLDDMRRQGYDNGANMHGKYNGVQARIRQLNPRTFFIPCSAHFLSLVL 944
            +++ E F+ F++  + TG ++ +     LQ++ V++D +  Q YD+  N+  K+N + A  ++  PR  +I C AHFL L +
Sbjct:  673 ILIKERFLGFVDTEEMTGTHLHRTIKTYLQQIGVDMDKIHGQAYDSTTNLKIKFNKIAAEFKKEEPRALYIHCYAHFLDLSI 754

HSP 2 Score: 48.9062 bits (115), Expect = 1.008e-16
Identity = 49/196 (25.00%), Postives = 88/196 (44.90%), Query Frame = 2 
Query:   56 IKGTTKDVVFCICCKIFSPNKFSLS----SNDGCRDGKNLSVIIKQHETSNGHTTAYSNRRELQVRLKSGTTMDD--INQKIIQSKTQHWRKVIERTLIRTLGGQNLELRGTCEKLFEPNKENLLKFIE*LGNYDP------IMSKHI*GIITSKIHTT*LRKTTQNKIVELLANKIKDHVLTQLKQAKYYSIILD 607
            ++ + KDV FC  C++F    FS      +  G  + K      ++HE S  H  +    RE Q     G   DD  I+ K I+   ++ + +IE  L   LG Q L LRG  + +   NK N L+ +E +   D       +M+  +    +++I         Q+ I+E++  ++   ++ ++  +  +SII D
Sbjct:  467 LENSKKDVAFCYSCQLFCQKYFSCGRESFATHGTSNWKKTLEKFRKHEKSEMHLKSLEFWREYQ--FCDGAVSDDLSIHSKQIEGNKKYLKLIIENILF--LGKQCLPLRGNDQSVSSVNKGNFLELLE-MRAKDKGEETFRLMNSQVDFYNSTQI---------QSDIIEIIKTEMLQDIVNEINDSSAFSIICD 648
[Close]
BLAST of TTF-type domain-containing protein vs. UniProt/SwissProt
Match: sp|Q9UJ78|ZMYM5_HUMAN (Zinc finger MYM-type protein 5 OS=Homo sapiens OX=9606 GN=ZMYM5 PE=1 SV=4)

HSP 1 Score: 60.077 bits (144), Expect = 4.729e-8
Identity = 33/104 (31.73%), Postives = 56/104 (53.85%), Query Frame = 2 
Query:    2 GRKFSCFHFYSRMSNGDK------IKGTTKDVVFCICCKIFSPNKFSLSSNDGCRDGKNLSVIIKQHETSNGHTTAYSNRRELQVRLKSGTTMDDINQKIIQSK 295
            GRKFS  ++   + NG+K      +  T+KD VFC+ CK+F   K  L + +GC+D ++LS I+ +HE S  H        +L+  LK    +D    ++ +++
Sbjct:  556 GRKFSETYYTRILPNGEKTTRSWLLYSTSKDSVFCLYCKLFGEGKNQLKNENGCKDWQHLSHILSKHEESEMHVNNSVKYSKLKSDLKKNKAIDAAEHRLYENE 659
[Close]
BLAST of TTF-type domain-containing protein vs. UniProt/SwissProt
Match: sp|A6QPH9|ZMYM5_BOVIN (Zinc finger MYM-type protein 5 OS=Bos taurus OX=9913 GN=ZMYM5 PE=2 SV=2)

HSP 1 Score: 58.9214 bits (141), Expect = 1.012e-7
Identity = 33/94 (35.11%), Postives = 53/94 (56.38%), Query Frame = 2 
Query:    2 GRKFSCFHFYSRMSNGDK------IKGTTKDVVFCICCKIFSPNKFSLSSNDGCRDGKNLSVIIKQHETSNGHTTAYSNRRELQVRLKSGTTMD 265
            GRKFS  ++   ++NG+K      +  T+KD VFC+ CK+F   K  L + +GCRD ++LS I+ +HE S  H        +L+  LK+   ++
Sbjct:  556 GRKFSETYYTRILANGEKTTRSWLLYSTSKDSVFCLYCKLFGEGKNQLKNENGCRDWQHLSHILSKHEESEMHINNSVKYSKLKSDLKTSKIVE 649
[Close]
BLAST of TTF-type domain-containing protein vs. UniProt/SwissProt
Match: sp|Q4R3D6|ZMYM5_MACFA (Zinc finger MYM-type protein 5 OS=Macaca fascicularis OX=9541 GN=ZMYM5 PE=2 SV=3)

HSP 1 Score: 58.5362 bits (140), Expect = 1.420e-7
Identity = 32/104 (30.77%), Postives = 57/104 (54.81%), Query Frame = 2 
Query:    2 GRKFSCFHFYSRMSNGDK------IKGTTKDVVFCICCKIFSPNKFSLSSNDGCRDGKNLSVIIKQHETSNGHTTAYSNRRELQVRLKSGTTMDDINQKIIQSK 295
            GRKFS  ++   + NG+K      +  T+KD VFC+ C++F   K  L + +GC+D ++LS I+ +HE S  H        +L+  LK    +D   +++ +++
Sbjct:  553 GRKFSETYYTRILPNGEKTTRSWLLYSTSKDSVFCLYCRLFGEGKNQLKNENGCKDWQHLSHILSKHEESEMHINNSVKYSKLKSDLKKNKAIDAAERRLYENE 656
[Close]
BLAST of TTF-type domain-containing protein vs. TrEMBL
Match: X1XM94 (TTF-type domain-containing protein OS=Acyrthosiphon pisum OX=7029 PE=4 SV=1)

HSP 1 Score: 202.986 bits (515), Expect = 6.645e-84
Identity = 106/213 (49.77%), Postives = 147/213 (69.01%), Query Frame = 2 
Query:    2 GRKFSCFHFYSRMSNGDKIKGT------TKDVVFCICCKIFSPNKFSLSSNDGCRDGKNLSVIIKQHETSNGHTTAYSNRRELQVRLKSGTTMDDINQKIIQSKTQHWRKVIER--TLIRTLGGQNLELRGTCEKLFEPNKENLLKFIE*LGNYDPIMSKHI*GIITSKIHTT*LRKTTQNKIVELLANKIKDHVLTQLKQAKYYSIILDCTP 616
            GR+F+  HF+ ++SNG ++K +      T D VFC CCK+F+  K SL   +G  D KN++  +KQHE S  H T++   +EL++R+ +  T+ +IN+KII+++ QHWR+VIER  +LIR LG QNL LRGT +KL   N  N LKFIE LG +DP+M +HI  I + +IHT  L K  QN+I+ LLA KI+ H+L  LK+AKYYSI+LDCTP
Sbjct:  200 GRRFTINHFFRKLSNGMEVKRSWLVYSGTGDSVFCYCCKLFNETKSSLGK-EGYHDWKNIAETLKQHERSPHHETSFLKWKELEIRINNSKTIGNINEKIIKTEIQHWRQVIERIISLIRVLGNQNLALRGTHDKLNLENNGNFLKFIEFLGKFDPVMKEHIRRITSDEIHTHYLGKEIQNEIINLLAKKIRLHILNCLKKAKYYSIVLDCTP 411

HSP 2 Score: 139.813 bits (351), Expect = 6.645e-84
Identity = 66/121 (54.55%), Postives = 92/121 (76.03%), Query Frame = 3 
Query:  645 IVFRFFSATESSSEKAVEVIVSEHFVTFLELHDTTGENMTKIAIDKLQELCVNLDDMRRQGYDNGANMHGKYNGVQARIRQLNPRTFFIPCSAHFLSLVLNDAVNICIQTVA-FDLI*CIY 1004
            ++FRF + +E + E    V ++EHFV F++L+DT+G NM K+ +DKL+E  V L+DMR QGYDNGANM GK++GVQARI +LN R F++PC+AH L+LVLND+ N C++ V+ F LI  IY
Sbjct:  421 MIFRFVTISEDTGE----VTINEHFVDFIQLYDTSGFNMIKVLLDKLREFEVKLEDMRGQGYDNGANMRGKHSGVQARILELNSRAFYVPCNAHTLNLVLNDSANCCLEAVSFFSLIQAIY 537
[Close]
BLAST of TTF-type domain-containing protein vs. TrEMBL
Match: H3A856 (TTF-type domain-containing protein OS=Latimeria chalumnae OX=7897 PE=4 SV=1)

HSP 1 Score: 173.326 bits (438), Expect = 6.521e-80
Identity = 84/210 (40.00%), Postives = 132/210 (62.86%), Query Frame = 2 
Query:    5 RKFSCFHFYSRMSNGDKIKGT------TKDVVFCICCKIFSPNKFSLSSNDGCRDGKNLSVIIKQHETSNGHTTAYSNRRELQVRLKSGTTMDDINQKIIQSKTQHWRKVIER--TLIRTLGGQNLELRGTCEKLFEPNKENLLKFIE*LGNYDPIMSKHI*GIITSKIHTT*LRKTTQNKIVELLANKIKDHVLTQLKQAKYYSIILDC 610
            RKF+  H+   ++NG+ +  T      + D +FC CCKIF+ N  S  ++DG RD KNLS I+  HE S  H +A+   +E++ RL    T+D  N++ + ++T+HWR V+ R   L RTL  QNL  +G  ++L+EP   N LKFIE +G +D +M + +  I ++  H   L K  QN++++LLA+KI+  +L+ +K++KYYS+ILDC
Sbjct:  137 RKFTPNHYMHHLTNGEAVARTWLLYSVSSDTIFCFCCKIFTLNVKSALASDGVRDWKNLSAILSSHEKSFDHISAFQTWKEMEERLNCNKTVDQYNRRTLSAETEHWRNVLHRLVALTRTLAVQNLTFQGHSDRLYEPGNGNFLKFIELMGMFDGVMKERLQRITSNDTHIHYLGKNIQNELIDLLASKIRGKILSMVKESKYYSVILDC 346

HSP 2 Score: 155.992 bits (393), Expect = 6.521e-80
Identity = 107/304 (35.20%), Postives = 161/304 (52.96%), Query Frame = 3 
Query:  645 IVFRFFSATESSSEKAVEVIVSEHFVTFLELHDTTGENMTKIAIDKLQELCVNLDDMRRQGYDNGANMHGKYNGVQARIRQLNPRTFFIPCSAHFLSLVLNDAVNICIQTVAFDLI*CI--------YY*SVLLN---------*WSLRCPT*NI*RQHFNNSIT----------SKNYLDAKGIIRNISNFKFVCSLVLWYDFLLQINLFR*MLRTQHLDLTLTLENLNATKSFLCNYRSXXXXXXXXXXXXXXXXXXXXXXGFFEKEPRVCRKSRQFLYESRDEPIVAPKINFRV-FFLIGY 1472
            ++ RF S    + E      + E F+ F++L D++GE MT++ + KL E+ + L DMR Q YDNGANM GK   VQ  +R+LN R FF+PC+ H L+L+L+DA   C   V F +I  I        Y   +LL           W  R       R     SI           +K++ +A+ I   + NFKF+CSLV+W+D L ++N+    L+    DL   +E L   + FL NYR + +F  ++  A++LA  L I + F E+     +K  QF Y++RDEP+V P+ +F+V FF + Y
Sbjct:  358 MIVRFVSTRPGNVE------IQECFLAFVKLDDSSGEGMTEVLLQKLNEMGLPLADMRGQSYDNGANMKGKNKEVQKWVRELNSRAFFVPCNTHSLNLILSDAAGCCTDAVNFGVIQAIFVYFSLSTYQWDILLKHVVKQLSETRWGSRVEAARAIRYDALLSIADDTMLTGTCGTKSHAEARSITGKVLNFKFLCSLVVWHDILFEVNIASKTLQVVEFDLHQAIEQLAVLQDFLQNYRLDHSFVSVLAIAQELAESLSIQQRFAEE----IQKKTQFDYKTRDEPVVNPEQSFKVNFFYVLY 651
[Close]
BLAST of TTF-type domain-containing protein vs. TrEMBL
Match: T2MBP3 (Zinc finger MYM-type protein 1 (Fragment) OS=Hydra vulgaris OX=6087 GN=ZMYM1 PE=2 SV=1)

HSP 1 Score: 160.229 bits (404), Expect = 2.864e-72
Identity = 108/321 (33.64%), Postives = 166/321 (51.71%), Query Frame = 3 
Query:  696 EVIVSEHFVTFLELHDTTGENMTKIAIDKLQELCVNLDDMRRQGYDNGANMHGKYNGVQARIRQLNPRTFFIPCSAHFLSLVLNDAVNICIQTVA-FDLI*CIY-Y*SVLLN*W---SLRCPT*NI*R---------------------------------QHFNNSITSKNYLDAKGIIRNISNFKFVCSLVLWYDFLLQINLFR*MLRTQHLDLTLTLENLNATKSFLCNYRSXXXXXXXXXXXXXXXXXXXXXXGFFEKEPRVCRKSRQFLYESRDEPIVAPKINFRVFFLIGYWASQFKQQMKYLPNFPNISSYLGF 1544
            E  + EHF+ F+ L  TTG  M +  I +L+E+   +D++R QGYDNGANM GK NGVQ +I  +NPR  F+PCSAH L+LV+NDA N C+   + FD++  +Y Y S   + W   +   PT  +                                        S  S    DAK +  +++ FKFV S+V+WY+ L ++N+    L+ + LD+   ++ L  T+++L + RS+  FA ++  A ++A +LEI    FE EP++ R+ +QF YE+ DEP+  PK NF+V F      +  +   +       I S  GF
Sbjct:  387 EFSIKEHFLGFVPLKKTTGAYMAETIIQQLEEMESPIDNLRGQGYDNGANMIGKNNGVQKKILNINPRALFVPCSAHTLNLVVNDAANCCLMATSFFDIVQRVYVYFSSSTHRWVVFTSHQPTLTVKPLSETRWERRIDAIKPLRYELGKIYDALLEIADDTSLTGSSGSTARSDAKALANSVAKFKFVVSIVVWYNILFELNITSKQLQAKDLDIHAAVQQLQHTQAYLVDCRSDIGFARMLVDAAEIAKDLEISLT-FEAEPQLRRRKKQFAYEAGDEPVRDPKQNFKVNFFFAILDTAIRSVEERFEQMRTIESVFGF 706

HSP 2 Score: 143.28 bits (360), Expect = 2.864e-72
Identity = 77/218 (35.32%), Postives = 127/218 (58.26%), Query Frame = 2 
Query:    5 RKFSCFHFYSRMSNGDKI------KGTTKDVVFCICCKIFSPNKFSLSS--NDGCRDGKNLSVIIKQHETSNGHTTAYSNRRELQVRLKSGTTMDDINQKIIQSKTQHWRKVIER--TLIRTLGGQNLELRGTCEKLFEPNKENLLKFIE*LGNYDPIMSKHI*GI---ITSKIHTT-*LRKTTQNKIVELLANKIKDHVLTQLKQAKYYSIILDCTP 616
            RKFS FH+  ++ NG+++          KD VFC CCK+F      +SS  + G  D KN++ I+  HE S  H   Y   +EL  RL+  +T+D    + ++++ ++W+++++R   L+R LG QNL  RGT E L+  N  N LKF++ L  +DP+M++H+  I   ++ + +T   L +  QN++++LL N IK  ++      KY+SI+LD TP
Sbjct:  147 RKFSVFHYLRKLPNGEELCCSWLLYSVLKDSVFCFCCKLFGMKAIGISSLTHTGSSDWKNMAAILSSHEKSPEHLQNYQKWKELHQRLQRDSTIDAEILRKMKNEEKYWQQILKRLIALVRVLGEQNLAFRGTNETLYSANNGNFLKFVQYLAIFDPLMNEHLQKISNKVSWRRYTKHYLGEDIQNELIQLLGNAIKKEIIQTANAMKYFSIVLDGTP 364

HSP 3 Score: 70.8626 bits (172), Expect = 7.091e-9
Identity = 63/192 (32.81%), Postives = 90/192 (46.88%), Query Frame = 2 
Query: 1457 FFNRILGIAIQATNEIFTQFSEYIELFGFLYNI-GSKKFTDDELLKHCKD*QFTLSSDG*SDINRVEFWNEILSI*RRL-DTPKAIQKVC*YIFTR------------LNLLKYSPTC**HFAYCQSYQSKFLVLKKVFQSSK*KLYLRSQMCQYRLVGLATISIEK*ISVQSDMEDLVTDFGELTEIKIHF 1990
            FF  IL  AI++  E F Q      +FGFLY+I G +  T  E+L+ C   +  L      D+   +   E+ SI RRL +  K+ Q V  +I  +            L +L   P          S +  F  LK +      K Y+RS MCQ RLVGLAT+SIE  ++ + D++D V DF +    K+ F
Sbjct:  678 FFFAILDTAIRSVEERFEQMRTIESVFGFLYHIHGLQSKTSQEILECCMKLESALQHGDNRDLVASDLCGELQSIARRLSEETKSPQDVFRFILCQNLEDSLPNLCIALRILLTLPVS------VASEERSFSKLKLI------KTYIRSSMCQDRLVGLATLSIEHKLADKLDLKDFVFDFAQKKARKVQF 857
[Close]
BLAST of TTF-type domain-containing protein vs. TrEMBL
Match: A0A452HM69 (Uncharacterized protein OS=Gopherus agassizii OX=38772 PE=4 SV=1)

HSP 1 Score: 115.546 bits (288), Expect = 2.944e-67
Identity = 63/165 (38.18%), Postives = 100/165 (60.61%), Query Frame = 2 
Query:  125 LSSNDGCRDGKNLSVIIKQHETSNGHTTAYSNRRELQVRLKSGTTMDDINQKIIQSKTQHWRKVIERTL--IRTLGGQNLELRGTCEKLFEPNKENLLKFIE*LGNYDPIMSKHI*GIITSKIHTT*LRKTTQNKIVELLANKIKDHVLTQLKQAKYYSIILDCT 613
            L +  G  D +NL   + +HETS  H  + +N  EL  RL SGTT++ + Q  + S+   W+ V++R+L  I  L  Q L    + + L+E N  N LK +E L  +D +M++H+  +   +IHT  L K TQN+I+EL++N +++ +L+ L+ A YYSII+DCT
Sbjct:   16 LLATAGFNDWRNLHQHLNEHETSKNHLCSLTNWIELSNRLCSGTTINAVQQHQLNSEILWWQAVLKRSLAIINFLAEQCLAFCRSSDILYENNNGNFLKLVELLAKFDNVMAEHVQRVKDGEIHTHYLGKNTQNEIIELISNGVRNEILSNLEHANYYSIIVDCT 180

HSP 2 Score: 113.62 bits (283), Expect = 2.944e-67
Identity = 88/297 (29.63%), Postives = 148/297 (49.83%), Query Frame = 3 
Query:  645 IVFRFFSATESSSEKAVEVIVSEHFVTFLELHDTTGENMTKIAIDKLQELCVNLDDMRRQGYDNGANMHGKYNGVQARIRQLNPRTFFIPCSAHFLSLVLNDAV--NICIQTVAFDLI*CIYY*S---VLLN*WSLRCPT*NI*RQHFNNSITSKNYL-------------------DAKGIIRNISNFKFVCSLVLWYDFLLQINLFR*MLRTQHLDLTLTLENLNATKSFLCNYRSXXXXXXXXXXXXXXXXXXXXXXGFFEKE---PRVCRKSRQFLYESRDEPIVAPKINFRV 1454
            IV RF    E++     EV + EHF+ F+ ++ TTG+ +T + + +L+   + L +MR QGYDNG+NM G++ GVQ RI  LN R FF PC AH L LV+          + + F     + Y +    + N +S       + ++H    +T K                      +A+ + + +  F+F C  V+W++ L QINL   +++   ++++     LN    +L  Y S+  F E +++A  +A +L+    F  ++   PR   K+RQF YE+ D+PI+ P   F+V
Sbjct:  191 IVLRFLKTDENA-----EVKICEHFLEFIPVNKTTGKALTDVILQRLEHYRIPLKNMRGQGYDNGSNMRGRHAGVQQRILHLNNRAFFSPCHAHSLDLVVXARTTGKCTAKNIEFKQSNAVSYFTTVQAIYNFFSASTHRWAVLKKHLEQKLTLKPLSQTRWESRIDDLSYDPSFRHEAETLAQKMMQFQFSCCTVIWHNILNQINLTSKVMQNITINISKAKMILNKMLEYLRKYHSDEEFEETVKEASTIAEDLDFEPTFAPQQFIRPR--EKTRQFCYEAHDDPILNPNKRFKV 480

HSP 3 Score: 78.9518 bits (193), Expect = 2.944e-67
Identity = 64/189 (33.86%), Postives = 96/189 (50.79%), Query Frame = 2 
Query: 1460 FNRILGIAIQATNEIFTQFSEYIELFGFLYNIGSKK--FTDDELLKHCKD*QFTLSSDG*SDINRVEFWNEILSI*RRLDTPKAIQKVC*YI-----FTR-----LNLLKYSPTC**HFAYCQSYQSKFLVLKKVFQSSK*KLYLRSQMCQYRLVGLATISIEK*ISVQSDMEDLVTDFGELTEIKIHF 1990
            F  IL +AI +  E F Q   + E+F FLY+IG+ K  F+ ++L+K C+D    LS+D  +DI+ VE ++E++++   +    +  KV  +I     FT      L +L   P          S Q  F  LK +      K YLRS M Q R+ GLA ISIE  I+ + D  +L+ D+  +   KI F
Sbjct:  483 FYCILDVAITSIEERFCQLHGHCEIFEFLYDIGNIKNQFSKEDLMKQCQDLYLALSTDNAADIDAVELYDELIALAELISPKTSPLKVLEFIARNVFFTPNTAITLRILLTLPVS------TASGQRSFSKLKLL------KNYLRSIMSQNRMSGLALISIESTIAKKLDFTNLLKDYASIKTRKIQF 659
[Close]
BLAST of TTF-type domain-containing protein vs. TrEMBL
Match: A0A0F8ARZ7 (Zinc finger MYM-type protein 1 OS=Larimichthys crocea OX=215358 GN=EH28_11148 PE=4 SV=1)

HSP 1 Score: 145.206 bits (365), Expect = 1.607e-66
Identity = 73/207 (35.27%), Postives = 121/207 (58.45%), Query Frame = 2 
Query:   26 FYSRMSNGDKIK------GTTKDVVFCICCKIFS--PNKFSLSSNDGCRDGKNLSVIIKQHETSNGHTTAYSNRRELQVRLKSGTTMDDINQKIIQSKTQHWRKVIERTL--IRTLGGQNLELRGTCEKLFEPNKENLLKFIE*LGNYDPIMSKHI*GIITSKIHTT*LRKTTQNKIVELLANKIKDHVLTQLKQAKYYSIILDCTP 616
            F  R+SNG+ IK          D  FC CCK+FS   NK  +    G  D  N++ +++QHE S  HT +    +EL +RL  G T+D I    ++++ + WR V+ R L   ++L  +NL  RG+ +KL++P+  N L+ +E L  YDP+M  H+  I   + H   L K  QN++++L++++I   ++ +++ +KY+S+ILDCTP
Sbjct:  128 FQRRLSNGEIIKRSWLSYSVKNDATFCFCCKLFSKKTNKIIVG---GVNDWSNINAVLRQHEGSPEHTKSMIKWKELDLRLSHGKTLDHIQMTALEAERKRWRDVLTRLLSITQSLAERNLAFRGSSDKLYQPDNGNFLREVELLAKYDPVMENHVSRIKDGETHAHYLSKDIQNELIQLVSDQILATIVAEVRHSKYFSLILDCTP 331

HSP 2 Score: 116.316 bits (290), Expect = 1.607e-66
Identity = 80/292 (27.40%), Postives = 127/292 (43.49%), Query Frame = 3 
Query:  705 VSEHFVTFLELHDTTGENMTKIAIDKLQELCVNLDDMRRQGYDNGANMHGKYNGVQARIRQLNPRTFFIPCSAHFLSLVLNDAVNICIQTVAFDLI*CIYY*SVLLN*WSLRCPT*NI*RQHFNNSITSKNYLD---------------------------------------AKGIIRNISNFKFVCSLVLWYDFLLQINLFR*MLRTQHLDLTLTLENLNATKSFLCNYRSXXXXXXXXXXXXXXXXXXXXXXGFFEKEPRVCRKSRQFLYESRDEPIVAPKINFRVFFL 1463
            + EHF+ F+ +  TTG N+T + +DKL +L +  D+ R Q YDNGANM GK+ GVQAR+ ++NPR  F+PC AH L+L++ DA       V F       Y   L   +S      +I ++H N  IT K++ D                                       A+ +   + +++F+   V+W + L + N    +L++  + L + ++ ++  K+ L  YR                           KE R+    + F YES DEP+V    N  V F 
Sbjct:  354 IKEHFLGFVNVEATTGLNLTTVILDKLADLKIPFDNCRGQAYDNGANMKGKHQGVQARLLRMNPRAVFVPCGAHTLNLIIADAAKSSKDAVGF-----FGYVQKLFTFFSAGTQRWSILKKHVN--ITVKSWSDTRWESRLQSVHAVRHQASKIREALLEARQTVNDPVAKVEAQSLAEEVGSYRFLICCVVWCEILSRTNTVNKLLQSASMQLDIAVQLISTAKASLTLYRDTGFSDAQTTAQSICEEMNVEP---VLKEKRLRTTKKHFSYESSDEPVVDALRNLEVNFF 635

HSP 3 Score: 44.669 bits (104), Expect = 1.607e-66
Identity = 43/171 (25.15%), Postives = 79/171 (46.20%), Query Frame = 2 
Query: 1457 FFNRILGIAIQATNEIFTQFSEYIELFGFLYNIGSK-KFTDDELLKHCKD*QFTLSSDG*SDINRVEFWNEILSI*RRLDTPKAIQKVC*YIFTRLNLLKYSPTC**HFAYCQSYQSKFLVLKKVFQSSK-*KLYLRSQMCQYRLVGLATISIEK*ISVQSDMEDLVTDFG 1963
            FFN ++  AI + +E F   ++  + +G + N  S  + +DD L+  C + +  L+ +  SDI+ V+   EI ++     +     ++  ++  + NL +  P          +        ++ F   K  K YLRS M Q RL GLA +SI   +  +   +D++ DF 
Sbjct:  634 FFNIVVDTAIASVDERFETLNKVKKQYGVVLNFSSACQMSDDPLMAECMEMEKALTFNEESDISGVDLAEEIKNLPPLPSSNMTAFELLSFLCEK-NLEELYPNLWIALRIGVTLPVTVASAERSFSKLKIIKSYLRSTMSQERLSGLAIMSINHDMGKKICYDDIIDDFA 803
[Close]
BLAST of TTF-type domain-containing protein vs. Ensembl Cavefish
Match: ENSAMXT00000037907.1 (pep primary_assembly:Astyanax_mexicanus-2.0:APWO02002089.1:152797:155023:-1 gene:ENSAMXG00000037599.1 transcript:ENSAMXT00000037907.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 153.68 bits (387), Expect = 7.897e-60
Identity = 84/213 (39.44%), Postives = 127/213 (59.62%), Query Frame = 2 
Query:    5 RKFSCFHFYSRMSNGDKIK------GTTKDVVFCICCKIFS-PNKFSLSSNDGCRDGKNLSVIIKQHETSNGHTTAYSNRRELQVRLKSGTTMDDINQKIIQSKTQHWRKVIERTL--IRTLGGQNLELRGTCEKLFEPNKENLLKFIE*LGNYDPIMSKHI*GIITSKIHTT*LRKTTQNKIVELLANKIKDHVLTQLKQAKYYSIILDCTP 616
            R+F+  +++ +M+NG+KI         + D VFC CC +F   +KF+LSS+ G R   N+   ++ HE S  H     N REL  RLK+GT +D   Q++   + QHW+ V+ R L  +  L  +N  LRG  EKLFEP+  N L  IE +  +DP+MS+H+  I   +I    L KT QN+++ L+  K KD ++ ++K AKY+S+I+DCTP
Sbjct:   51 RQFTVDNYHMKMNNGEKINWNWLVYSLSSDSVFCFCCTVFERESKFALSSS-GFRSWINIHSHLRDHEKSKIHCANMQNLRELAERLKTGTAIDSACQELRALEVQHWKAVLRRILAIVCNLAERNQALRGHSEKLFEPHNGNFLGQIELMAQFDPVMSEHLRRIDKKEIKDHYLSKTIQNELISLVGQKTKDAIVQKVKDAKYFSVIMDCTP 262

HSP 2 Score: 70.4774 bits (171), Expect = 7.897e-60
Identity = 65/272 (23.90%), Postives = 112/272 (41.18%), Query Frame = 3 
Query:  705 VSEHFVTFLELHDTTGENMTKIAIDKLQELCVNLDDMRRQGYDNGANMHGKYNGVQARIRQLNPRTFFIPCSAHFLSLVLNDAVNICIQTVAFDLI*CIYY*SVLLN----*WSLRCPT*NI*RQHFNNSITSKNYL--------------DAKGIIRNISNFKFVCSLVLWYDFLLQINLFR*MLRTQHLDLTLTLENLNATKSFLCNYRSXXXXXXXXXXXXXXXXXXXXXXGFFEKEPRVCRKSRQFLYESRDEPIVAPKINF-RVFFL 1463
            +SEHFV F  + DT+G  +      +L+ + +N+ D R Q YDNG+NM G   GVQ         T F          +L    N+   +V    I   +    + N     W  R  +    R  +   I + + L               A+ + + + +++F+  +V+WY+ L  IN    +L++ ++ +       +  K FL  YR     +   E  +        +     ++ R  RK   FLYE +DE  + P+ +F + FFL
Sbjct:  287 ISEHFVGFFSVQDTSGRGLCNTLTKELKNMKLNIADCRGQSYDNGSNMMGHKQGVQKSAGDKPKGTVFFCVVCDLFFGILQRLYNLFSSSVHRWSILQRHVKLTVKNLSTTRWECRIESVKALRHQYPEMIEALSALTEHAAEKKDGETLYSAQNLCKELMSWQFILCVVIWYNVLFHINHVSKLLQSPNMAIDAVKRETDHVKQFLQEYRDHGISSAKTEAREIAEKLQVDMTFPVARQRRTTRK---FLYEGKDEVQLTPEQHFNQEFFL 555

HSP 3 Score: 48.1358 bits (113), Expect = 7.897e-60
Identity = 52/183 (28.42%), Postives = 74/183 (40.44%), Query Frame = 2 
Query: 1457 FFNRILGIAIQATNEIFTQFSEYIELFGFLYNIGS-KKFTDDELLKHCKD*QFTLSS----DG*SDINRVEFWNEILSI*RRLDTPKAIQKVC*YIFTRLNLLKYSPTC**HFAYCQSYQSKFLVLKKVFQSSK*KLYLRSQMCQYRLVGLATISIEK*ISVQSDMEDLVTDFGELTEIKIHF 1990
            FF  ++  A+ + +E FTQ   +  LFGFLY+  + KK   D L   CK  + TL       G  DI    +   +L +   L     +                 P          S +  F  LK +      K +LRS M Q RL GLA ISIE+ +    +MED++  F E     + F
Sbjct:  553 FFLPLIDTALISISERFTQVDVFFSLFGFLYSANNMKKAIQDTLEDSCKKLERTLGQPRPGSGSEDILDYIYKENLLELYGNLSIALLLLLT-------------LPIT------VASGERSFSSLKLI------KHFLRSTMSQERLTGLAMISIEQRVRRSLNMEDIINAFAETKTRMVQF 710
[Close]
BLAST of TTF-type domain-containing protein vs. Ensembl Cavefish
Match: ENSAMXT00000036272.1 (pep primary_assembly:Astyanax_mexicanus-2.0:20:11935414:11938921:1 gene:ENSAMXG00000041670.1 transcript:ENSAMXT00000036272.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 115.546 bits (288), Expect = 1.487e-59
Identity = 66/213 (30.99%), Postives = 110/213 (51.64%), Query Frame = 2 
Query:    2 GRKFSCFHFYSRMSNGDKIK------GTTKDVVFCICCKIFSPNKFSLSSNDGCRDGKNLSVIIKQHETSNGHTTAYSNRRELQVRLKSGTTMDDINQKIIQSKTQHWRKVIER--TLIRTLGGQNLELRGTCEKLFEPNKENLLKFIE*LGNYDPIMSKHI*GIITSKIHTT*LRKTTQNKIVELLANKIKDHVLTQLKQAKYYSIILDCTP 616
            GR F     Y  + N +KIK          + VFC  CK+F      L+   G  D  N+++ ++ HE S  HT      REL  RL+    +D     +++++ + W  V++R  ++  +L  +NL  RG+ + L+  +  N LK +E L  +D +   H+  I      T  L + TQN+I+E++ ++    ++ ++KQAKYY+IILDCTP
Sbjct:  130 GRAFHAGLQYKSLPNKEKIKRSWMVYSAQSNAVFCFPCKLFGTKSTRLTKT-GYSDWSNINICLRSHEGSPDHTKCMLQWRELDRRLRKNLAIDQQELSLMEAERKRWHDVLKRLFSITLSLATRNLPFRGSSQSLYVQDNGNFLKEVELLAQFDSVTEGHVARIKDDASRTHYLGQQTQNEIIEIICSQTIQTIVAKIKQAKYYAIILDCTP 341

HSP 2 Score: 102.834 bits (255), Expect = 1.487e-59
Identity = 74/288 (25.69%), Postives = 127/288 (44.10%), Query Frame = 3 
Query:  705 VSEHFVTFLELHDTTGENMTKIAIDKLQELCVNLDDMRRQGYDNGANMHGKYNGVQARIRQLNPRTFFIPCSAHFLSLVLNDAVNICIQTVAF----DLI*CIY------------Y*SVLLN*WS-------------LRCPT*NI------*RQHFNNSITSKNYLDAKGIIRNISNFKFVCSLVLWYDFLLQINLFR*MLRTQHLDLTLTLENLNATKSFLCNYRSXXXXXXXXXXXXXXXXXXXXXXGFFEKEPRVCRKSRQFLYESRDEPIVAPKINFRVFFL 1463
            + E+F+ ++ + +TTG N++ + ++KL+ L +  +D R Q YDNGANM GK  GVQAR+ QLNPR  F+PC+AH ++LV++DA       +++      + C +            +  + L  WS             +R     +       RQ     +      +A+G+   + +F+F+   V+W + L   +    +L++  + L +    +   K  L  YR       I    +         E    K+ R+    RQF YE+ DEP    +    V F 
Sbjct:  364 IREYFLGYMNVVETTGLNLSNVVLEKLRALGIPFEDCRGQAYDNGANMKGKRQGVQARLLQLNPRAAFVPCAAHTMNLVISDAAKSSTDAISYFGYLQRLFCFFSAATQRWDILLKHVKLTLKSWSDVRWESRLQSVVAVRSQVKEVREALLEARQAVTEPVARS---EAQGLAEEVGSFRFLICTVVWAEVLSVTSQVNKVLQSSSMQLDIAARLIKTAKESLTKYRQSGFSEAIESAKELCEALNIEPEL---KQKRLRSTKRQFGYEAPDEPFSDAQKRLEVEFF 645

HSP 3 Score: 50.8322 bits (120), Expect = 1.487e-59
Identity = 49/181 (27.07%), Postives = 79/181 (43.65%), Query Frame = 2 
Query: 1457 FFNRILGIAIQATNEIFTQFSEYIELFGFLYNIGS-KKFTDDELLKHCKD*QFTLSSDG*SDINRVEFWNEILSI*RRLDTPKA-----------IQKVC*YIFTRLNLLKYSPTC**HFAYCQSYQSKFLVLKKVFQSSK*KLYLRSQMCQYRLVGLATISIEK*ISVQSDMEDLVTDFG 1963
            FFN ++  A+ +  E F   S+  + FG L +       +  +L  HC D +  L+  G +DI+  E   EI+++ +      A           +Q+V   ++  L +    P          S +  F  LK +      K YLRS M Q RL GLA ISI   ++    ++DL++DF 
Sbjct:  644 FFNHVVDSALTSLQERFETMSQVRDTFGVLLDFQKVHGISKQDLHNHCMDVEKKLTDKGEADIDGQEMMQEIINLPQLSPQTTAFELLTYLHDNSLQEVYPNLWIALRIALTLPVT------VASAERSFSKLKLI------KTYLRSTMGQERLSGLAVISINAEVAHSLSLDDLISDFA 812

HSP 4 Score: 23.0978 bits (48), Expect = 1.487e-59
Identity = 8/10 (80.00%), Postives = 9/10 (90.00%), Query Frame = 1 
Query:  613 PDIIHKEQMT 642
            PDI HKEQM+
Sbjct:  341 PDISHKEQMS 350
[Close]
BLAST of TTF-type domain-containing protein vs. Ensembl Cavefish
Match: ENSAMXT00000044961.1 (pep primary_assembly:Astyanax_mexicanus-2.0:APWO02000032.1:419978:423709:1 gene:ENSAMXG00000036481.1 transcript:ENSAMXT00000044961.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 135.576 bits (340), Expect = 2.386e-53
Identity = 76/212 (35.85%), Postives = 120/212 (56.60%), Query Frame = 2 
Query:    5 RKFSCFHFYSRMSNGDKI------KGTTKDVVFCICCKIFSPNKFSLSSNDGCRDGKNLSVIIKQHETSNGHTTAYSNRRELQVRLKSGTTMDDINQKIIQSKTQHWRKVIER--TLIRTLGGQNLELRGTCEKLFEPNKENLLKFIE*LGNYDPIMSKHI*GIITSKIHTT*LRKTTQNKIVELLANKIKDHVLTQLKQAKYYSIILDCTP 616
            R+F+  ++   M NG+KI         + D VFC  C +F     +LS        KNL+  +K+HE S GH     N  ELQ RL++ TT+D   Q ++Q + +HW+ VI R   +I  L  +N  LRGT  +L++P+  N L  +E +  +DP+M++HI  I   +     L  T QN+I+ L+ NK+ + ++ + ++AKYYS+I+DCTP
Sbjct:  105 RRFTKENYRRTMKNGEKILRSWLVYSMSTDSVFCFPCTVFGKRDNALSKL-WFHKWKNLTYHLKEHEYSKGHCDNMRNWHELQRRLQNKTTIDQRQQALMQIEIEHWKAVIRRVIAIICHLAERNQALRGTTSELYDPHNGNFLAQVELMAKFDPVMNEHIRRIQNQEAKVHYLSGTIQNEIIALIGNKVLEEIVRRAQRAKYYSVIMDCTP 315

HSP 2 Score: 94.3597 bits (233), Expect = 2.386e-53
Identity = 42/95 (44.21%), Postives = 66/95 (69.47%), Query Frame = 3 
Query:  699 VIVSEHFVTFLELHDTTGENMTKIAIDKLQELCVNLDDMRRQGYDNGANMHGKYNGVQARIRQLNPRTFFIPCSAHFLSLVLNDAVNICIQTVAF 983
            V ++EHF  F+++ DT+G+ +T++ +D LQ+  +++ D R Q YDNG+NM G+  GVQARI QLN +   IPCS+H L+LV+ DA    + + +F
Sbjct:  336 VSIAEHFFGFIDVEDTSGKGLTEVLLDHLQKHNLSISDCRGQSYDNGSNMMGQKQGVQARILQLNNKALCIPCSSHTLNLVVADAAKSSVLSTSF 430
[Close]
BLAST of TTF-type domain-containing protein vs. Ensembl Cavefish
Match: ENSAMXT00000025204.2 (pep primary_assembly:Astyanax_mexicanus-2.0:12:7364240:7371214:-1 gene:ENSAMXG00000024490.2 transcript:ENSAMXT00000025204.2 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 125.561 bits (314), Expect = 1.333e-49
Identity = 75/212 (35.38%), Postives = 116/212 (54.72%), Query Frame = 2 
Query:    5 RKFSCFHFYSRMSNGDKI------KGTTKDVVFCICCKIFSPNKFSLSSNDGCRDGKNLSVIIKQHETSNGHTTAYSNRRELQVRLKSGTTMDDINQKIIQSKTQHWRKVIER--TLIRTLGGQNLELRGTCEKLFEPNKENLLKFIE*LGNYDPIMSKHI*GIITSKIHTT*LRKTTQNKIVELLANKIKDHVLTQLKQAKYYSIILDCTP 616
            R+F+  ++   M NG+KI         + D VFC  C +      +LS N G    KNL+  +K+HE S GH     N  ELQ RL++ TT+D   Q ++Q + +HW+ VI R   +I  L  +N  LRGT   L++P+  N L  +E +  +DP+M++HI      +     L  T QN+I+ L+ NK+ + ++TQ    + YS+I+DCTP
Sbjct:   55 RRFTKENYRRTMKNGEKILRSWLVYSMSTDSVFCFPCTVLGKRDNALS-NCGFHKWKNLTYHLKEHEYSKGHCDNMRNWHELQRRLQNKTTIDQRQQTLMQIEIEHWKAVIRRVIAIICHLAERNQALRGTTSVLYDPHNGNFLAQVELMAKFDPVMNEHIRRRQNQEAKVHYLSGTIQNEIIALIGNKVLEEIITQ----RDYSVIMDCTP 261

HSP 2 Score: 91.6633 bits (226), Expect = 1.333e-49
Identity = 41/95 (43.16%), Postives = 66/95 (69.47%), Query Frame = 3 
Query:  699 VIVSEHFVTFLELHDTTGENMTKIAIDKLQELCVNLDDMRRQGYDNGANMHGKYNGVQARIRQLNPRTFFIPCSAHFLSLVLNDAVNICIQTVAF 983
            V ++EHF  F+++ DT+G+ +T++ +D LQ+  +++ D R Q YDNG+NM G+  GV+ARI QLN +   IPCS+H L+LV+ DA    + + +F
Sbjct:  282 VSIAEHFFGFIDVEDTSGKGLTEVLLDHLQKHNLSISDCRGQSYDNGSNMMGQKQGVRARILQLNNKALCIPCSSHKLNLVVADAAKSSVLSTSF 376

HSP 3 Score: 42.3578 bits (98), Expect = 3.362e-9
Identity = 23/47 (48.94%), Postives = 29/47 (61.70%), Query Frame = 2 
Query: 1847 KLYLRSQMCQYRLVGLATISIEK*ISVQSDMEDLVTDFGELTEIKIH 1987
            K Y+RS M Q RL GLA +SIE+ +    DMED+V  F    E K+H
Sbjct:  686 KTYMRSTMGQERLTGLALMSIEREVCRSLDMEDIVVAFA---EAKVH 729

HSP 4 Score: 38.891 bits (89), Expect = 3.362e-9
Identity = 18/38 (47.37%), Postives = 26/38 (68.42%), Query Frame = 1 
Query: 1708 PKSLLIYIYTSKFVEVFPNLLIALRILPKLPVKVSSAE 1821
            P  +L YIY+ K ++++  L IALR+L  LPV V+S E
Sbjct:  639 PFDMLNYIYSEKLLDLYSTLSIALRLLLTLPVSVASGE 676
[Close]
BLAST of TTF-type domain-containing protein vs. Ensembl Cavefish
Match: ENSAMXT00000055782.1 (pep primary_assembly:Astyanax_mexicanus-2.0:APWO02001476.1:1798:4262:-1 gene:ENSAMXG00000042376.1 transcript:ENSAMXT00000055782.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 98.5969 bits (244), Expect = 7.321e-48
Identity = 71/212 (33.49%), Postives = 106/212 (50.00%), Query Frame = 2 
Query:    5 RKFSCFHFYSRMSNGDKIK------GTTKDVVFCICCKIFSPNKFSLSSNDGCRDGKNLSVIIKQHETSNGHTTAYSNRRELQVRLKSGTTMDDINQKIIQSKTQHWRKVIERTL--IRTLGGQNLELRGTCEKLFEPNKENLLKFIE*LGNYDPIMSKHI*GIITSKIHTT*LRKTTQNKIVELLANKIKDHVLTQLKQAKYYSIILDCTP 616
            R+F+  +++ +M+NG+KI         + D VFC CC +F             R+ K    I+K+   S  H     N REL  RLK+                QH + V+ R L  +  L  +N  LRG  EKLFEP+  N L  IE +     +MS+H+  I   +I    L KT QN+++ L+  K KD ++ ++K AKY+S+I+DCTP
Sbjct:  111 RRFTVDNYHMKMNNGEKINRNWLVYSLSSDSVFCFCCTVFE------------RESK---FIMKK---SKIHRANMQNWRELAERLKT---------------VQHRKAVLRRILAIVCHLAERNQALRGHSEKLFEPHNGNFLGQIELMAQ---LMSEHLRRIDKKEIKDHYLSKTIQNELISLVGQKTKDAIVQKVKDAKYFSVIMDCTP 286

HSP 2 Score: 84.7297 bits (208), Expect = 7.321e-48
Identity = 69/288 (23.96%), Postives = 116/288 (40.28%), Query Frame = 3 
Query:  705 VSEHFVTFLELHDTTGENMTKIAIDKLQELCVNLDDMRRQGYDNGANMHGKYNGVQARIRQLNPRTFFIPCSAHFLSLVLNDAVNICIQTVAFDLI*CIYY---------*SVL------------LN*WSLRCPT*NI*RQHFNNSITSKNYL--------------DAKGIIRNISNFKFVCSLVLWYDFLLQINLFR*MLRTQHLDLTLTLENLN-----ATKSFLCNYRSXXXXXXXXXXXXXXXXXXXXXXGFFEKEPRVCRKSRQFLYESRDEPIVAPKINF 1448
            +SEHFV F  + DT+G  +     ++L+ + +N+ D R Q Y+NG+NM G   GVQ R+ ++N +   +PCS+H L+LV+ DA    + +V F  I    Y          S+L               W  R  +    R  +   I + + L               A+ + + + +++F+  +V+WY+ L  IN    +L+   L       + N       +    NYR                                 R +R+FLYE +DE  + P+  F
Sbjct:  311 ISEHFVGFFSVQDTSGRGLCNTLTEELKHMKLNIADCRGQSYNNGSNMMGHKQGVQKRVLEINQKALCVPCSSHSLNLVVADAAKSSVLSVTFFGILQWLYNLFSSSVHRWSILQRHVKLTVKNLSTTRWECRIESVKALRHQYPEMIEALSVLTEHAAEKKDGETLYSAQNLCKELMSWQFILCVVIWYNVLFHINHVSKLLQKPELFSPRIPGSWNFIAKTEARELQRNYR---------------------------------RTTRKFLYEGKDEVQLTPEQRF 565

HSP 3 Score: 48.521 bits (114), Expect = 7.321e-48
Identity = 55/191 (28.80%), Postives = 78/191 (40.84%), Query Frame = 2 
Query: 1460 FNRILGIAIQATNEIFTQFSEYIELFGFLY--NIGSKKFTDDELLKHCKD*QFTLSSDG*SDINRVEFWNEILSI*RRLDTPKAIQKVC*YIFTR------------LNLLKYSPTC**HFAYCQSYQSKFLVLKKVFQSSK*KLYLRSQMCQYRLVGLATISIEK*ISVQSDMEDLVTDFGELTEIKIHF 1990
            F  ++  A+ + +E FTQ   +  LFGFLY  N   K   +D L   CK  + TL      D+  +E    +      + +P  I     YI+              L LL   P          S +  F  LK +      K +LRS M Q RL GLA ISIE+ +    +MED++  F E     + F
Sbjct:  570 FLPLIDTALISISERFTQVDVFFSLFGFLYYANNMKKAIQEDTLEDSCKKLERTLGDVDSQDL-VLEVTAAVSVFPDHISSPADILD---YIYKENLLELYGNLSIALRLLLTLPIT------VASGERSFSSLKLI------KNFLRSTMSQERLTGLAMISIEQRVRRSLNMEDIINAFAETKTRMVQF 744
[Close]
BLAST of TTF-type domain-containing protein vs. Ensembl Medaka
Match: ENSORLT00000028133.1 (zinc finger MYM-type protein 1-like [Source:NCBI gene;Acc:111948955])

HSP 1 Score: 125.561 bits (314), Expect = 6.507e-53
Identity = 72/211 (34.12%), Postives = 120/211 (56.87%), Query Frame = 2 
Query:   14 SCFHFYSR--MSNGDKIKGT------TKDVVFCICCKIFSPNKFSLSSNDGCRDGKNLSVIIKQHETSNGHTTAYSNRRELQVRLKSGTTMDDINQKIIQSKTQHWRKVIER--TLIRTLGGQNLELRGTCEKLFEPNKENLLKFIE*LGNYDPIMSKHI*GIIT-SKIHTT*LRKTTQNKIVELLANKIKDHVLTQLKQAKYYSIILDCT 613
            SC H Y R  + +G+KI  T       K+ +FC CCK+FS    +L+++ G  + K+ S  +  HE S  H       +EL  R++SG T+D     +++ +   WR V+ R   ++++L  +NL LRG  E LF  +  N LK +E +  +DPIM  H+  ++  +  H + +    QN++++LL++KI   ++  +K+AKY+SIILDCT
Sbjct:  163 SCHHHYFRKTLVSGEKIARTWLMYSKVKNSLFCFCCKLFSNKNINLTTS-GTANWKHASTYLTAHEKSPEHLNCMKAWKELSGRIRSGKTIDKQEMALLEEERVRWRAVLTRLIAIVQSLAVRNLALRGHTETLFTSSNGNFLKEVELMARFDPIMKDHLNRVLRGTASHNSYIGHHVQNELIDLLSSKILSAIVDDIKKAKYFSIILDCT 372

HSP 2 Score: 102.834 bits (255), Expect = 6.507e-53
Identity = 72/272 (26.47%), Postives = 127/272 (46.69%), Query Frame = 3 
Query:  705 VSEHFVTFLELHDTTGENMTKIAIDKLQELCVNLDDMRRQGYDNGANMHGKYNGVQARIRQLNPRTFFIPCSAHFLSLVLNDAVNICIQTVA-FDLI*CIY-Y*SVLLN*WSLRCPT*NI*RQHFN--------NSITSKNY----------------------LDAKGIIRNISNFKFVCSLVLWYDFLLQINLFR*MLRTQHLDLTLTLENLNATKSFLCNYRSXXXXXXXXXXXXXXXXXXXXXXGFFEKEPRVCRKSRQFLYESRDEP 1424
            + EHF+ FLE  ++TG+++  + +++L+EL ++ +D R Q YDNGANM GK  GVQAR+ + NPR  F+PC AH L+LV+ DA    +  ++ F ++  +Y   S     W++     +I  + +          SI    Y                       +A+ +   + +++F    V+W+D L  I     ++++ ++ + L +  L  T+  L +YR+       +   +              K+ R+     QF YES DEP
Sbjct:  396 IREHFMGFLEAEESTGQHLASMILNRLEELGISFEDCRGQSYDNGANMKGKNKGVQARLLEKNPRALFLPCGAHTLNLVVCDAAKRSVDAMSYFGVLQKLYTLFSASAQRWAILKSQVSITLKSWTETRWESKIKSIEPMRYQGAAVREALIEVRDKTKDPVIKAEAQSLSEEVGSYRFNICTVVWHDILSTIKHVSKLMQSPNMHVDLAVSLLKKTEQSLQSYRANGFVNAQMAAKEMCKEMNVEA---ILKQKRIRSTKCQFSYESHDEP 664
[Close]
BLAST of TTF-type domain-containing protein vs. Ensembl Medaka
Match: ENSORLT00000042294.1 (zinc finger MYM-type protein 1-like [Source:NCBI gene;Acc:110016639])

HSP 1 Score: 125.561 bits (314), Expect = 6.507e-53
Identity = 72/211 (34.12%), Postives = 120/211 (56.87%), Query Frame = 2 
Query:   14 SCFHFYSR--MSNGDKIKGT------TKDVVFCICCKIFSPNKFSLSSNDGCRDGKNLSVIIKQHETSNGHTTAYSNRRELQVRLKSGTTMDDINQKIIQSKTQHWRKVIER--TLIRTLGGQNLELRGTCEKLFEPNKENLLKFIE*LGNYDPIMSKHI*GIIT-SKIHTT*LRKTTQNKIVELLANKIKDHVLTQLKQAKYYSIILDCT 613
            SC H Y R  + +G+KI  T       K+ +FC CCK+FS    +L+++ G  + K+ S  +  HE S  H       +EL  R++SG T+D     +++ +   WR V+ R   ++++L  +NL LRG  E LF  +  N LK +E +  +DPIM  H+  ++  +  H + +    QN++++LL++KI   ++  +K+AKY+SIILDCT
Sbjct:  163 SCHHHYFRKTLVSGEKIARTWLMYSKVKNSLFCFCCKLFSNKNINLTTS-GTANWKHASTYLTAHEKSPEHLNCMKAWKELSGRIRSGKTIDKQEMALLEEERVRWRAVLTRLIAIVQSLAVRNLALRGHTETLFTSSNGNFLKEVELMARFDPIMKDHLNRVLRGTASHNSYIGHHVQNELIDLLSSKILSAIVDDIKKAKYFSIILDCT 372

HSP 2 Score: 102.834 bits (255), Expect = 6.507e-53
Identity = 72/272 (26.47%), Postives = 127/272 (46.69%), Query Frame = 3 
Query:  705 VSEHFVTFLELHDTTGENMTKIAIDKLQELCVNLDDMRRQGYDNGANMHGKYNGVQARIRQLNPRTFFIPCSAHFLSLVLNDAVNICIQTVA-FDLI*CIY-Y*SVLLN*WSLRCPT*NI*RQHFN--------NSITSKNY----------------------LDAKGIIRNISNFKFVCSLVLWYDFLLQINLFR*MLRTQHLDLTLTLENLNATKSFLCNYRSXXXXXXXXXXXXXXXXXXXXXXGFFEKEPRVCRKSRQFLYESRDEP 1424
            + EHF+ FLE  ++TG+++  + +++L+EL ++ +D R Q YDNGANM GK  GVQAR+ + NPR  F+PC AH L+LV+ DA    +  ++ F ++  +Y   S     W++     +I  + +          SI    Y                       +A+ +   + +++F    V+W+D L  I     ++++ ++ + L +  L  T+  L +YR+       +   +              K+ R+     QF YES DEP
Sbjct:  396 IREHFMGFLEAEESTGQHLASMILNRLEELGISFEDCRGQSYDNGANMKGKNKGVQARLLEKNPRALFLPCGAHTLNLVVCDAAKRSVDAMSYFGVLQKLYTLFSASAQRWAILKSQVSITLKSWTETRWESKIKSIEPMRYQGAAVREALIEVRDKTKDPVIKAEAQSLSEEVGSYRFNICTVVWHDILSTIKHVSKLMQSPNMHVDLAVSLLKKTEQSLQSYRANGFVNAQMAAKEMCKEMNVEA---ILKQKRIRSTKCQFSYESHDEP 664
[Close]
BLAST of TTF-type domain-containing protein vs. Ensembl Medaka
Match: ENSORLT00000045044.1 (zinc finger MYM-type protein 1-like [Source:NCBI gene;Acc:111948193])

HSP 1 Score: 125.561 bits (314), Expect = 6.507e-53
Identity = 72/211 (34.12%), Postives = 120/211 (56.87%), Query Frame = 2 
Query:   14 SCFHFYSR--MSNGDKIKGT------TKDVVFCICCKIFSPNKFSLSSNDGCRDGKNLSVIIKQHETSNGHTTAYSNRRELQVRLKSGTTMDDINQKIIQSKTQHWRKVIER--TLIRTLGGQNLELRGTCEKLFEPNKENLLKFIE*LGNYDPIMSKHI*GIIT-SKIHTT*LRKTTQNKIVELLANKIKDHVLTQLKQAKYYSIILDCT 613
            SC H Y R  + +G+KI  T       K+ +FC CCK+FS    +L+++ G  + K+ S  +  HE S  H       +EL  R++SG T+D     +++ +   WR V+ R   ++++L  +NL LRG  E LF  +  N LK +E +  +DPIM  H+  ++  +  H + +    QN++++LL++KI   ++  +K+AKY+SIILDCT
Sbjct:  163 SCHHHYFRKTLVSGEKIARTWLMYSKVKNSLFCFCCKLFSNKNINLTTS-GTANWKHASTYLTAHEKSPEHLNCMKAWKELSGRIRSGKTIDKQEMALLEEERVRWRAVLTRLIAIVQSLAVRNLALRGHTETLFTSSNGNFLKEVELMARFDPIMKDHLNRVLRGTASHNSYIGHHVQNELIDLLSSKILSAIVDDIKKAKYFSIILDCT 372

HSP 2 Score: 102.834 bits (255), Expect = 6.507e-53
Identity = 72/272 (26.47%), Postives = 127/272 (46.69%), Query Frame = 3 
Query:  705 VSEHFVTFLELHDTTGENMTKIAIDKLQELCVNLDDMRRQGYDNGANMHGKYNGVQARIRQLNPRTFFIPCSAHFLSLVLNDAVNICIQTVA-FDLI*CIY-Y*SVLLN*WSLRCPT*NI*RQHFN--------NSITSKNY----------------------LDAKGIIRNISNFKFVCSLVLWYDFLLQINLFR*MLRTQHLDLTLTLENLNATKSFLCNYRSXXXXXXXXXXXXXXXXXXXXXXGFFEKEPRVCRKSRQFLYESRDEP 1424
            + EHF+ FLE  ++TG+++  + +++L+EL ++ +D R Q YDNGANM GK  GVQAR+ + NPR  F+PC AH L+LV+ DA    +  ++ F ++  +Y   S     W++     +I  + +          SI    Y                       +A+ +   + +++F    V+W+D L  I     ++++ ++ + L +  L  T+  L +YR+       +   +              K+ R+     QF YES DEP
Sbjct:  396 IREHFMGFLEAEESTGQHLASMILNRLEELGISFEDCRGQSYDNGANMKGKNKGVQARLLEKNPRALFLPCGAHTLNLVVCDAAKRSVDAMSYFGVLQKLYTLFSASAQRWAILKSQVSITLKSWTETRWESKIKSIEPMRYQGAAVREALIEVRDKTKDPVIKAEAQSLSEEVGSYRFNICTVVWHDILSTIKHVSKLMQSPNMHVDLAVSLLKKTEQSLQSYRANGFVNAQMAAKEMCKEMNVEA---ILKQKRIRSTKCQFSYESHDEP 664
[Close]
BLAST of TTF-type domain-containing protein vs. Ensembl Medaka
Match: ENSORLT00000041223.1 (zinc finger MYM-type protein 1 [Source:NCBI gene;Acc:101155882])

HSP 1 Score: 43.8986 bits (102), Expect = 1.792e-8
Identity = 30/87 (34.48%), Postives = 45/87 (51.72%), Query Frame = 3 
Query:  705 VSEHFVTFLELHDTTGENMTKIAIDKLQELCVN--LDDMRRQGYDNGANMHGKYNGVQARIRQLNPRTFFIPCSAHFLSLVLNDAVN 959
            V E FV F ++  T+G+    IA   ++ L  N  LD +  Q ++         NGVQA++++  P   FI C AH LSLVL+   +
Sbjct:  272 VKERFVRFEDV--TSGKRADDIAGLVIKFLLENECLDKVVAQCFEGATVTSSGLNGVQAKVKESAPLALFIHCYAHQLSLVLSQGAS 356

HSP 2 Score: 35.039 bits (79), Expect = 1.792e-8
Identity = 36/187 (19.25%), Postives = 86/187 (45.99%), Query Frame = 2 
Query:   80 VFCICCKIFSPNKFSLSSNDGCRDGKNLSVIIKQHETSNGHT-------TAYSNRRELQVRLKSGTTMDDINQKIIQSKTQHWRKVIERTL--IRTLGGQNLELRGTCEKLFEPNKENLLKFIE*LGNYDPIMSKHI*GIITSKIHTT*LRKTTQNKIVELLANKIKDHVLTQLKQAKYYSIILDCT 613
            ++C  C +F+ ++  + S+ G  +   L+   K+H+ + GH        T   +R ELQ+   +    +  N+K+ ++     R++++R +  +  LG Q L  RG  E     N+ N  + +  +   +  +  H    +++    +      Q+ ++  +   I+D +  ++K A + S++++ T
Sbjct:   74 LYCWECLLFALDRHGVWSHTGFGNLTCLTKAAKKHQNTAGHLQSIVLSKTFGESRVELQLNEHARRETELHNEKVKKN-----REILKRLIDCVLFLGKQELSFRGRDESGGSSNRGNYCELLSVIAESNTDLHYH----LSTNEAFSGTSGKIQDDLISAIDEVIRDEIRREVKNAPFVSVMVEET 251
[Close]
BLAST of TTF-type domain-containing protein vs. Ensembl Medaka
Match: ENSORLT00000027735.1 (pep primary_assembly:ASM223467v1:9:30712608:30715295:1 gene:ENSORLG00000030268.1 transcript:ENSORLT00000027735.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 51.6026 bits (122), Expect = 2.293e-6
Identity = 31/94 (32.98%), Postives = 49/94 (52.13%), Query Frame = 3 
Query:  705 VSEHFVTFLELHDTTGENMTKIAIDKLQELCVNLDD-MRRQGYDNGANMHGKYNGVQARIRQLNPRTFFIPCSAHFLSLVLNDAVNICIQTVAF 983
            V E F+ F          +++  I+ LQ+  ++  + +  Q YD  + M GK  GVQARI+   P  F++ C+AH L+LVL D+V    +   F
Sbjct:  341 VCECFLAFEAAQRLNAAALSQKIIEILQKHGLDYKNHLVGQAYDGASVMSGKNTGVQARIKSEAPLAFYVHCNAHCLNLVLVDSVKFIPEANCF 434
[Close]
BLAST of TTF-type domain-containing protein vs. Planmine SMEST
Match: SMESG000026738.1 (SMESG000026738.1)

HSP 1 Score: 105.145 bits (261), Expect = 3.919e-46
Identity = 65/217 (29.95%), Postives = 111/217 (51.15%), Query Frame = 2 
Query:    2 GRKFSCFHFYSRMSNGDK------IKGTTKDVVFCICCKIFSPNKFSLSSNDGCRDGKNLSVIIKQHETSNGHTTAYSNRRELQVRLKSGTTMDDINQKIIQSKTQHWRKVIER--TLIRTLGGQNLELRGTCEKLFEPNKENLLKFIE*LGNYDPIMSKHI*GIITSKIHTT*----LRKTTQNKIVELLANKIKDHVLTQLKQAKYYSIILDCTP 616
            GR FS  +FY ++ NG+K      I     D  FC CCK+F   +  L  N+G +D +++S  + +HE +  H    +  ++L++ LK  TT+D   Q+   ++ + W ++++R  ++++ L GQ L  RG                      +D IM+ HI  +             L    QN+I+ +LA +I+ ++LT +K+AKY+S+ILDCTP
Sbjct:  142 GRSFSKVYFYRKLPNGEKFNREWLIYSPKNDATFCFCCKLFGKQEIKLV-NEGFKDWQHISDNLSRHEKTTLHIENCTCWKKLELNLKRKTTIDKNMQRYYDAEKKRWCQIVKRMISVVQFLAGQCLAFRG---------------------KFDDIMADHIKRVQEPNAPKNRMPHYLGNRFQNEIIAILATQIQKYILTSIKEAKYFSVILDCTP 336

HSP 2 Score: 100.138 bits (248), Expect = 3.919e-46
Identity = 48/99 (48.48%), Postives = 62/99 (62.63%), Query Frame = 3 
Query:  687 KAVEVIVSEHFVTFLELHDTTGENMTKIAIDKLQELCVNLDDMRRQGYDNGANMHGKYNGVQARIRQLNPRTFFIPCSAHFLSLVLNDAVNICIQTVAF 983
            K  EV V E+F+ F +    TGE+     I KL  L +N+ DMR QGYDNG+NM GK+ G+Q RI    PR  F+PC+AH L+L +NDA N+   TV F
Sbjct:  354 KNYEVEVRENFIGFYQAKKCTGESFYDFLIQKLNYLELNISDMRVQGYDNGSNMSGKHRGLQKRILDNYPRALFMPCNAHTLNLAINDAANVSFSTVDF 452
[Close]
BLAST of TTF-type domain-containing protein vs. Planmine SMEST
Match: SMESG000036749.1 (SMESG000036749.1)

HSP 1 Score: 99.3673 bits (246), Expect = 4.324e-41
Identity = 47/99 (47.47%), Postives = 62/99 (62.63%), Query Frame = 3 
Query:  687 KAVEVIVSEHFVTFLELHDTTGENMTKIAIDKLQELCVNLDDMRRQGYDNGANMHGKYNGVQARIRQLNPRTFFIPCSAHFLSLVLNDAVNICIQTVAF 983
            K  EV V E+F+ F +    TGE+     I KL  + +N+ DMR QGYDNG+NM GK+ G+Q RI    PR  F+PC+AH L+L +NDA N+   TV F
Sbjct:  303 KNYEVEVRENFIGFYQAKKCTGESFYDFLIQKLNYIELNISDMRGQGYDNGSNMSGKHRGLQKRILDNYPRALFMPCNAHTLNLAINDAANVSFSTVDF 401

HSP 2 Score: 88.9669 bits (219), Expect = 4.324e-41
Identity = 62/211 (29.38%), Postives = 104/211 (49.29%), Query Frame = 2 
Query:    2 GRKFSCFHFYSRMSNGDKIKGTTKDVVFCICCKIFSPNKFSLSSNDGCRDGKNLSVIIKQHETSNGHTTAYSNRRELQVRLKSGTTMDDINQKIIQSKTQHWRKVIER--TLIRTLGGQNLELRGTCEKLFEPNKENLLKFIE*LGNYDPIMSKHI*GIITSKIHTT*----LRKTTQNKIVELLANKIKDHVLTQLKQAKYYSIILDCTP 616
            GR FS  +FY ++ NG+K                   N+  L      R   ++  +I   + +  H   +   +      +  TT+D   Q+   ++ + W ++I+R  ++++ L GQ L  RG+  KL+E N  N LK IE +G +D IM+ HI  +             L    QN+I+ +LA +I+ ++LT +K+AKY+S+ILDCTP
Sbjct:   99 GRSFSKVYFYRKLPNGEKF------------------NREWLQ-----RLATHIRQLISSRKNNAAHRKLHLLEKLELNLKRK-TTIDKNMQRYYDAEKKRWCQIIKRMISMVQFLAGQCLAFRGSSGKLYEKNNGNFLKAIEMIGKFDDIMADHIKRVQEPNAPKNRMPHYLGNRFQNEIIAILATQIQKYILTSIKEAKYFSVILDCTP 285
[Close]
BLAST of TTF-type domain-containing protein vs. Planmine SMEST
Match: SMESG000069312.1 (SMESG000069312.1)

HSP 1 Score: 107.071 bits (266), Expect = 1.660e-36
Identity = 70/219 (31.96%), Postives = 110/219 (50.23%), Query Frame = 2 
Query:    2 GRKFSCFHFYSRMSNGDKIKGT------TKDVVFCICCKIFSPNKFSLSSNDGCRDGKNL---SVIIKQHETSNGHTTAYSNRRELQVRLKSGTTMDDINQKIIQSKTQHWRKVIERTL--IRTLGGQNLELRGTCEKLFEPNKENLLKFI---E*LGNYDPIMSKHI*GIITSKIHTT*LRKTTQNKIVELLANKIKDHVLTQLKQAKYYSIILDCTP 616
            GR      F  R++NGD+I  T       K   +C CC +F  +  +  S     +G N       +  HE S  H  +++  +E + R+ SG  +D   Q  +Q++ Q WR V++R L  ++ L  QNL LRG  E L   N  N+  F+   + L  YDP++S HI     +    + L   TQN+ + LLA+K+++ +L  +K+ KYY I+ D TP
Sbjct:  156 GRSSHSSWFTRRLANGDEINQTWLLYSPLKSSAYCFCCLLFPKSINNQRSGLTLPEGFNKLRKPEKMSAHENSPTHRASFTAWKEAERRIMSGKGIDAELQAQMQNEKQKWRDVLKRLLSCVKFLASQNLALRGHAESLATNNSSNVGNFLATLKLLAEYDPLLSNHIDHARQNPGSVSYLSPQTQNESISLLASKVRNKLLNDIKRNKYYGILFDSTP 374

HSP 2 Score: 65.855 bits (159), Expect = 1.660e-36
Identity = 58/197 (29.44%), Postives = 82/197 (41.62%), Query Frame = 3 
Query:  699 VIVSEHFVTFLELHDTTGENMTKIAIDKLQELCVNLDDMRRQGYDNGANMHGKYNGVQARIRQLNPRTFFIPCSAHFLSLV-LNDAVNICIQTVAFDLI*CIY-Y*S-----------VLLN--------*WSLRCPT*NI*RQHFN------------NSITSKNYLDAKGIIRNISNFKFVCSLVLWYDFLLQIN 1190
            V + E F+ F+ELH      +  +  D L+   + LDD R Q YDN A M G  +G+Q RI   NPR  F+ C+ H L+L  ++ A    +    F  I  IY Y S           V+ N         WS R           N            NS T     DA+ ++ NI +F F+  L  W+  L +I+
Sbjct:  399 VTIKESFLGFIELHAKDAATLEHVIADTLEADNLRLDDCRSQCYDNAALMSGHISGLQQRICNRNPRAIFVNCNNHSLNLAGMHSAKQDAVAVTFFRTIKSIYLYFSRSTLRWNELKNVISNTVKRECETRWSARADAVKAVHNGVNEIVGLLEIFSADNSQTQDTRADAERLLANILDFNFLVLLHFWHQILGKID 595
[Close]
BLAST of TTF-type domain-containing protein vs. Planmine SMEST
Match: SMESG000047334.1 (SMESG000047334.1)

HSP 1 Score: 134.42 bits (337), Expect = 2.077e-32
Identity = 75/217 (34.56%), Postives = 124/217 (57.14%), Query Frame = 2 
Query:    2 GRKFSCFHFYSRMSNGDK------IKGTTKDVVFCICCKIFSPNKFSLSSNDGCRDGKNLSVIIKQHETSNGHTTAYSNRRELQVRLKSGTTMDDINQKIIQSKTQHWRKVIER--TLIRTLGGQNLELRGTCEKLFEPNKENLLKFIE*LGNYDPIMSKHI*GIITSKIHTT*----LRKTTQNKIVELLANKIKDHVLTQLKQAKYYSIILDCTP 616
            GR FS  +FY ++ NG+K      I     D +FC CCK+F   +  L  N+G  D +++S  + +HE +  H   Y+  ++L++ LK  TT+D   Q+   ++ + W ++++R  ++++ L GQ L  RG+   L+E N  N LK IE +G +D IM+ HI  +             L    QN+I+ +LA +I+ ++LT +K+AKY+S+ILDCTP
Sbjct:  271 GRSFSKVYFYRKLPNGEKFNRELLIYSPKNDAIFCFCCKLFGKQEIKLV-NEGFNDWQHISDNLSRHEKTTLHIENYTCWKKLELNLKRKTTIDKNMQRYYDAEKKRWCQIVKRMISVVQFLAGQCLAFRGSSGILYEKNNGNFLKAIEMIGKFDDIMADHIKRVQEPNAPKNRMPHYLGNRFQNEIIAILATQIQKYILTSIKEAKYFSVILDCTP 486

HSP 2 Score: 77.411 bits (189), Expect = 1.856e-14
Identity = 35/68 (51.47%), Postives = 46/68 (67.65%), Query Frame = 3 
Query:  780 KLQELCVNLDDMRRQGYDNGANMHGKYNGVQARIRQLNPRTFFIPCSAHFLSLVLNDAVNICIQTVAF 983
            +L  L +N+ DMR QGYDNG+NM GK+  +Q RI    PR  F+PC+AH L+L +NDA N+   TV F
Sbjct:  509 ELNYLELNISDMRGQGYDNGSNMSGKHRRLQKRILDNYPRALFMPCNAHTLNLAINDAANVSFSTVDF 576
[Close]
BLAST of TTF-type domain-containing protein vs. Planmine SMEST
Match: SMESG000061124.1 (SMESG000061124.1)

HSP 1 Score: 120.939 bits (302), Expect = 6.545e-28
Identity = 75/217 (34.56%), Postives = 124/217 (57.14%), Query Frame = 2 
Query:    2 GRKFSCFHFYSRMSNGDK------IKGTTKDVVFCICCKIFSPNKFSLSSNDGCRDGKNLSVIIKQHETSNGHTTAYSNRRELQVRLKSGTTMDDINQKIIQSKTQHWRKVIER--TLIRTLGGQNLELRGTCEKLFEPNKENLLKFIE*LGNYDPIMSKHI*GII---TSKIHTT*LRKTT-QNKIVELLANKIKDHVLTQLKQAKYYSIILDCTP 616
            GR FS  +FY ++ NG+K      I     D  FC CCK+F   +  L  N+G  D +++S  + +HE +  H    +  ++L++ LK  TT+D   Q+   ++ + W ++++R  ++++ L GQ L  RG+  KL+E N  N LK IE +G +D  M+ HI  +      K H    +    QN+I+ +LA +I+ ++LT +K+AKY+S+ILDCTP
Sbjct:  142 GRSFSKVYFYRKLPNGEKFNREWLIYSPKNDATFCFCCKLFGKQEIKLV-NEGFNDWQHISDNLSRHEKTTLHIENCTCWKKLKLNLKRKTTIDKNMQRYYDAEKKRWCQIVKRMISVVQFLAGQCLAFRGSSGKLYEKNNGNFLKAIEMIGKFDDTMADHIKRVQEPNAPKNHMPHYQGNRFQNEIIAILATQIQKYILTSIKEAKYFSVILDCTP 357

HSP 2 Score: 78.5666 bits (192), Expect = 1.160e-14
Identity = 33/67 (49.25%), Postives = 47/67 (70.15%), Query Frame = 3 
Query:  783 LQELCVNLDDMRRQGYDNGANMHGKYNGVQARIRQLNPRTFFIPCSAHFLSLVLNDAVNICIQTVAF 983
            ++++ + + DMR QGYDNG+NM GK+ G+Q RI    PR  F+PC+AH L+L +NDA N+   TV F
Sbjct:  362 VEQITMVISDMRGQGYDNGSNMSGKHRGLQKRILDNYPRALFMPCNAHTLNLAINDAANVSFSTVDF 428

HSP 3 Score: 44.669 bits (104), Expect = 2.491e-8
Identity = 50/184 (27.17%), Postives = 79/184 (42.93%), Query Frame = 2 
Query: 1457 FFNRILGIAIQATNEIFTQFSEYIELFGFLYNIGSKKFTD---DELLKHCKD*QFTLSSDG*SDINRVEFWNEILSI*RRLDTPKAIQKVC*YIF------------TRLNLLKYSPTC**HFAYCQSYQSKFLVLKKVFQSSK*KLYLRSQMCQYRLVGLATISIEK*ISVQSDMEDLVTDFG 1963
            FFN IL  AI +    F   S +   FGFLY     KF D   +E+ K C D           DI+ VE + E++S+   +   K  +++  +++            T L LL   P       +  S +  F  LK +      K +LR+ M Q  L  ++ I+IE  I+  +++E  V +F 
Sbjct:  621 FFNVILDTAISSLTTRFETLSGFERCFGFLY-----KFIDMEHEEIKKSCFDLHNKFKDGESCDISGVELYQELVSLKIIIKDRKQPEELIKFLYKYNLETSFPNVATSLKLLLTVP------VFVASGERSFSKLKII------KNHLRTSMTQECLSNISIIAIENEIADSTNIEGAVEEFA 787

HSP 4 Score: 33.4982 bits (75), Expect = 2.491e-8
Identity = 30/122 (24.59%), Postives = 64/122 (52.46%), Query Frame = 3 
Query: 1104 DAKGIIRNISNFKFVCSLVLWYDFLLQINLFR*MLRTQHLDLTLTLENLNATKSFLCNYRSXXXXXXXXXXXXXXXXXXXXXXGF-FEKEPRVCRKSRQFLYESRDEPI-VAPKINFRVFFL 1463
            +A+ +   + ++KF+ S+++WY+ L +++    M++    +++   E++     F  + R++ +F   ++ + +L + LE    F  E   R     +QF YE RDE I   PK +F++ F 
Sbjct:  502 EAECLANKLKSYKFISSIIIWYEILEKVDFISKMMQKVSWNISSCAESIKEVLKFFKSIRNDESFENYLQISNELCVALETEPDFPAEISVRSRHHRKQFSYE-RDEDIQFTPKEHFQISFF 622
The following BLAST results are available for this feature:
BLAST of TTF-type domain-containing protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ZMYM12.295e-1730.49zinc finger MYM-type containing 1 [Source:HGNC Sym... [more]
ZMYM12.295e-1730.49zinc finger MYM-type containing 1 [Source:HGNC Sym... [more]
ZMYM12.295e-1730.49zinc finger MYM-type containing 1 [Source:HGNC Sym... [more]
ZMYM12.295e-1730.49zinc finger MYM-type containing 1 [Source:HGNC Sym... [more]
ZMYM59.847e-931.73zinc finger MYM-type containing 5 [Source:HGNC Sym... [more]
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BLAST of TTF-type domain-containing protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of TTF-type domain-containing protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of TTF-type domain-containing protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 1
Match NameE-valueIdentityDescription
CR762475.12.633e-2239.78pep chromosome:GRCz11:4:55494751:55498830:1 gene:E... [more]
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BLAST of TTF-type domain-containing protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 3
Match NameE-valueIdentityDescription
ENSXETT00000043220.19.344e-3542.55pep primary_assembly:Xenopus_tropicalis_v9.1:7:364... [more]
slc10a62.776e-1034.52solute carrier family 10 (sodium/bile acid cotrans... [more]
tbx182.981e-933.33T-box 18 [Source:Xenbase;Acc:XB-GENE-489907][more]
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BLAST of TTF-type domain-containing protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 3
Match NameE-valueIdentityDescription
Zmym12.155e-1331.71zinc finger, MYM domain containing 1 [Source:MGI S... [more]
Zmym12.155e-1331.71zinc finger, MYM domain containing 1 [Source:MGI S... [more]
Zmym15.912e-1131.71zinc finger, MYM domain containing 1 [Source:MGI S... [more]
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BLAST of TTF-type domain-containing protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 4
Match NameE-valueIdentityDescription
sp|Q5SVZ6|ZMYM1_HUMAN1.008e-1630.49Zinc finger MYM-type protein 1 OS=Homo sapiens OX=... [more]
sp|Q9UJ78|ZMYM5_HUMAN4.729e-831.73Zinc finger MYM-type protein 5 OS=Homo sapiens OX=... [more]
sp|A6QPH9|ZMYM5_BOVIN1.012e-735.11Zinc finger MYM-type protein 5 OS=Bos taurus OX=99... [more]
sp|Q4R3D6|ZMYM5_MACFA1.420e-730.77Zinc finger MYM-type protein 5 OS=Macaca fascicula... [more]
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BLAST of TTF-type domain-containing protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
X1XM946.645e-8449.77TTF-type domain-containing protein OS=Acyrthosipho... [more]
H3A8566.521e-8040.00TTF-type domain-containing protein OS=Latimeria ch... [more]
T2MBP32.864e-7233.64Zinc finger MYM-type protein 1 (Fragment) OS=Hydra... [more]
A0A452HM692.944e-6738.18Uncharacterized protein OS=Gopherus agassizii OX=3... [more]
A0A0F8ARZ71.607e-6635.27Zinc finger MYM-type protein 1 OS=Larimichthys cro... [more]
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BLAST of TTF-type domain-containing protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ENSAMXT00000037907.17.897e-6039.44pep primary_assembly:Astyanax_mexicanus-2.0:APWO02... [more]
ENSAMXT00000036272.11.487e-5930.99pep primary_assembly:Astyanax_mexicanus-2.0:20:119... [more]
ENSAMXT00000044961.12.386e-5335.85pep primary_assembly:Astyanax_mexicanus-2.0:APWO02... [more]
ENSAMXT00000025204.21.333e-4935.38pep primary_assembly:Astyanax_mexicanus-2.0:12:736... [more]
ENSAMXT00000055782.17.321e-4833.49pep primary_assembly:Astyanax_mexicanus-2.0:APWO02... [more]
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BLAST of TTF-type domain-containing protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of TTF-type domain-containing protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of TTF-type domain-containing protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of TTF-type domain-containing protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ENSORLT00000028133.16.507e-5334.12zinc finger MYM-type protein 1-like [Source:NCBI g... [more]
ENSORLT00000042294.16.507e-5334.12zinc finger MYM-type protein 1-like [Source:NCBI g... [more]
ENSORLT00000045044.16.507e-5334.12zinc finger MYM-type protein 1-like [Source:NCBI g... [more]
ENSORLT00000041223.11.792e-834.48zinc finger MYM-type protein 1 [Source:NCBI gene;A... [more]
ENSORLT00000027735.12.293e-632.98pep primary_assembly:ASM223467v1:9:30712608:307152... [more]
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BLAST of TTF-type domain-containing protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000026738.13.919e-4629.95SMESG000026738.1[more]
SMESG000036749.14.324e-4147.47SMESG000036749.1[more]
SMESG000069312.11.660e-3631.96SMESG000069312.1[more]
SMESG000047334.12.077e-3234.56SMESG000047334.1[more]
SMESG000061124.16.545e-2834.56SMESG000061124.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30028697 ID=SMED30028697|Name=TTF-type domain-containing protein|organism=Schmidtea mediterranea sexual|type=transcript|length=1998bp
AGGTAGAAAATTTTCCTGCTTTCATTTTTATAGCCGAATGTCTAACGGTG
ATAAAATTAAAGGCACTACAAAAGACGTTGTATTTTGCATTTGCTGTAAA
ATATTCAGTCCGAATAAATTCTCCTTGTCATCGAATGATGGATGCCGAGA
TGGGAAAAATCTTTCTGTTATTATCAAACAACATGAAACATCAAATGGCC
ACACTACTGCATATTCAAATCGGAGAGAGCTGCAGGTGAGACTTAAATCA
GGTACTACCATGGATGACATTAATCAGAAAATAATTCAATCTAAAACGCA
ACATTGGCGAAAAGTTATTGAAAGAACATTAATTAGGACTCTTGGTGGAC
AAAATCTAGAATTAAGAGGAACCTGTGAAAAACTTTTCGAGCCAAATAAA
GAAAATCTTTTGAAATTTATTGAATAATTAGGAAACTATGATCCTATTAT
GAGTAAACATATTTAAGGAATAATAACAAGTAAAATTCACACAACCTAAC
TAAGAAAAACAACTCAAAATAAAATCGTTGAATTGCTTGCCAATAAAATC
AAAGATCACGTCTTAACACAACTAAAACAAGCAAAGTACTACTCAATTAT
TTTAGATTGTACCCCGATATAATCCACAAGGAGCAGATGACAGAATTGTT
TTTAGGTTTTTCAGTGCAACTGAATCATCTTCAGAAAAAGCAGTGGAAGT
CATAGTTTCTGAGCACTTCGTGACTTTTCTTGAATTACATGATACAACTG
GAGAAAATATGACAAAAATTGCAATCGATAAGTTACAGGAATTATGCGTA
AATCTTGATGACATGAGAAGACAAGGGTACGATAATGGAGCCAACATGCA
CGGAAAATATAATGGTGTTCAAGCCAGAATTCGTCAACTGAACCCCCGAA
CTTTTTTCATACCTTGTAGTGCCCACTTTCTCAGTTTGGTATTAAACGAT
GCAGTTAATATTTGCATACAAACTGTCGCATTTGATTTAATTTAATGCAT
TTATTATTAAAGTGTATTACTAAATTAGTGGAGTTTACGATGCCCTACTT
GAAATATCTGAAGACAACACTTTAACAACTCCATCACGAGTAAAAATTAC
CTAGATGCTAAGGGAATAATCAGAAATATTTCAAACTTCAAATTTGTTTG
CTCCTTGGTATTGTGGTATGACTTTTTATTGCAAATTAACCTTTTCAGAT
AAATGCTACGAACACAGCATTTAGACTTGACTCTGACATTAGAGAATTTA
AACGCTACCAAATCTTTTCTATGTAATTATCGTTCTGAGGCAGCTTTTGC
AGAAATAATTGAAAAGGCTAAAAAATTAGCAATCGAACTTGAAATTTTGG
AAGGATTTTTTGAGAAAGAACCCCGCGTTTGCAGAAAGAGTCGACAATTT
TTATACGAAAGTCGTGATGAACCGATAGTAGCACCAAAAATAAACTTTAG
AGTATTTTTTTTAATCGGATATTGGGCATCGCAATTCAAGCAACAAATGA
AATATTTACCCAATTTTCCGAATATATCGAGTTATTTGGGTTTCTATACA
ATATCGGCAGTAAGAAATTTACGGATGACGAATTATTGAAACATTGTAAG
GACTAGCAGTTCACGCTTTCATCAGATGGCTAATCAGACATCAACCGGGT
AGAATTTTGGAATGAAATTCTATCTATATGAAGACGACTTGATACTCCAA
AAGCGATCCAAAAAGTTTGTTAATATATATTTACACGTCTAAATTTGTTG
AAGTATTCCCCAACCTGTTGATAGCACTTCGCATACTGCCAAAGTTACCA
GTCAAAGTTTCTAGTGCTGAAAAAAGTTTTTCAAAGCTCAAAATAAAAAT
TATATCTGAGATCACAGATGTGTCAATATCGTTTAGTTGGTCTAGCAACG
ATTTCCATAGAAAAATAAATTTCTGTTCAATCAGACATGGAGGATTTGGT
TACGGATTTTGGAGAATTAACAGAGATAAAAATCCACTTTTAATTATT
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protein sequence of SMED30028697-orf-1

>SMED30028697-orf-1 ID=SMED30028697-orf-1|Name=SMED30028697-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=142bp
GRKFSCFHFYSRMSNGDKIKGTTKDVVFCICCKIFSPNKFSLSSNDGCRD
GKNLSVIIKQHETSNGHTTAYSNRRELQVRLKSGTTMDDINQKIIQSKTQ
HWRKVIERTLIRTLGGQNLELRGTCEKLFEPNKENLLKFIE*
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protein sequence of SMED30028697-orf-2

>SMED30028697-orf-2 ID=SMED30028697-orf-2|Name=SMED30028697-orf-2|organism=Schmidtea mediterranea sexual|type=polypeptide|length=129bp
MLRTQHLDLTLTLENLNATKSFLCNYRSEAAFAEIIEKAKKLAIELEILE
GFFEKEPRVCRKSRQFLYESRDEPIVAPKINFRVFFLIGYWASQFKQQMK
YLPNFPNISSYLGFYTISAVRNLRMTNY*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: cellular component
TermDefinition
GO:0016020membrane
GO:0016021integral component of membrane
Vocabulary: molecular function
TermDefinition
GO:0046983protein dimerization activity
GO:0003676nucleic acid binding
Vocabulary: INTERPRO
TermDefinition
IPR025398DUF4371