SMED30028687

Overview
NameSMED30028687
Smed IDSMED30028687
Length (bp)8551
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of SMED30028687 (SMED30028687) t-SNE clustered cells

Violin plots show distribution of expression levels for SMED30028687 (SMED30028687) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of SMED30028687 (SMED30028687) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for SMED30028687 (SMED30028687) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30028687

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 6

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
nervous systemSMED30028687SMESG000062746.1 SMESG000003172.1 dd_Smed_v4_417_1_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
epidermisSMED30028687SMESG000062746.1 SMESG000003172.1 dd_Smed_v4_417_1_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
neoblastSMED30028687SMESG000062746.1 SMESG000003172.1 dd_Smed_v4_417_1_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
neoblastSMED30028687 dd_Smed_v4_13631_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
epidermisSMED30028687SMESG000062746.1 SMESG000003172.1 dd_Smed_v4_417_1_1dd_Smed_v4PMID:28292427
Wurtzel et al., 2017		whole organism asexual adult single-cell RNA-sequencing evidence
epidermisSMED30028687SMESG000003172.1 dd_Smed_v4_417_0_1dd_Smed_v4PMID:28292427
Wurtzel et al., 2017		whole organism asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of SMED30028687 vs. Ensembl Human
Match: PAK2 (p21 (RAC1) activated kinase 2 [Source:HGNC Symbol;Acc:HGNC:8591])

HSP 1 Score: 129.413 bits (324), Expect = 4.706e-30
Identity = 82/258 (31.78%), Postives = 140/258 (54.26%), Query Frame = -2 
Query:  271 KKLGIGAFAKVKLCKNKLSGRVFALK---MPKNKNINAILNEISIFSTLKSSPSMILFHGIYLHSNKLCIAMEYISGKTLESVLKDENSLDYSLKLQFVFQILQQIKSLHDAGIIHRDISCNNIMIYKENQNAKLIDFGLSISVKGLNTDAIELSGKYGTPWYMAPELLTHEPYSNKIDIWSVGVVAVKIFSGERPYTYLNPTKFQAKIAKDKTIEL-DPQNFSKDVFDFLSPCFKSDPKERPTVDDLLSSKMFQINR 1032
            +K+G GA   V    +   G+  A+K   + K      I+NEI +   LK+ P+++ F   YL  ++L + MEY++G +L  V+  E  +D +       + LQ ++ LH   +IHRDI  +N+++  E  + KL DFG    +     +  + S   GTP++MAPE++T + Y  K+DIWS+G++A+++  GE PY   NP +    IA + T EL +P+  S    DFL+ C + D ++R +  +LL     ++ +
Sbjct:  253 EKIGQGASGTVFTATDVALGQEVAIKQINLQKQPKKELIINEILVMKELKN-PNIVNFLDSYLVGDELFVVMEYLAGGSLTDVVT-ETCMDEAQIAAVCRECLQALEFLHANQVIHRDIKSDNVLLGMEG-SVKLTDFGFCAQI---TPEQSKRSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMVEGEPPYLNENPLRALYLIATNGTPELQNPEKLSPIFRDFLNRCLEMDVEKRGSAKELLQHPFLKLAK 504
[Close]
BLAST of SMED30028687 vs. Ensembl Human
Match: PAK1 (p21 (RAC1) activated kinase 1 [Source:HGNC Symbol;Acc:HGNC:8590])

HSP 1 Score: 122.479 bits (306), Expect = 5.831e-30
Identity = 71/213 (33.33%), Postives = 121/213 (56.81%), Query Frame = -2 
Query:  292 ILNEISIFSTLKSSPSMILFHGIYLHSNKLCIAMEYISGKTLESVLKDENSLDYSLKLQFVFQILQQIKSLHDAGIIHRDISCNNIMIYKENQNAKLIDFGLSISVKGLNTDAIELSGKYGTPWYMAPELLTHEPYSNKIDIWSVGVVAVKIFSGERPYTYLNPTKFQAKIAKDKTIEL-DPQNFSKDVFDFLSPCFKSDPKERPTVDDLLSS 927
            I+NEI +    K+ P+++ +   YL  ++L + MEY++G +L  V+  E  +D         + LQ ++ LH   +IHRDI  +NI++  +  + KL DFG    +     +  + S   GTP++MAPE++T + Y  K+DIWS+G++A+++  GE PY   NP +    IA + T EL +P+  S    DFL+ C + D ++R +  +LL +
Sbjct:   34 IINEILVMRENKN-PNIVNYLDSYLVGDELWVVMEYLAGGSLTDVVT-ETCMDEGQIAAVCRECLQALEFLHSNQVIHRDIKSDNILLGMDG-SVKLTDFGFCAQI---TPEQSKRSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMIEGEPPYLNENPLRALYLIATNGTPELQNPEKLSAIFRDFLNRCLEMDVEKRGSAKELLQA 240
[Close]
BLAST of SMED30028687 vs. Ensembl Human
Match: NEK5 (NIMA related kinase 5 [Source:HGNC Symbol;Acc:HGNC:7748])

HSP 1 Score: 122.479 bits (306), Expect = 1.705e-29
Identity = 81/261 (31.03%), Postives = 139/261 (53.26%), Query Frame = -2 
Query:  298 MDNIEVLKKLGIGAFAKVKLCKNKLSGRVFALK------MPKNKNINAILNEISIFSTLKSSPSMILFHGIYLHSNKLCIAMEYISGKTLESVLKDENSLDYSLK--LQFVFQILQQIKSLHDAGIIHRDISCNNIMIYKENQNAKLIDFGLSISVKGLNTDAIELSGK-YGTPWYMAPELLTHEPYSNKIDIWSVGVVAVKIFSGERPYTYLNPTKFQAKIAKDKTIELDPQNFSKDVFDFLSPCFKSDPKERPTVDDLL 1053
            MD  +V+K +G GAF K  L K K   +   +K      MP  +   A   E+ +   +K  P+++ F   +  + +L I MEY  G  L   +  +  + +S    L +  QI   +K +HD  I+HRDI   NI + K    AKL DFG++   + LN +++EL+    GTP+Y++PE+  ++PY+NK DIWS+G V  ++ + + P+   N  +   KI +     + P  FS+++   +S  F+  P++RP+++ +L
Sbjct:    1 MDKYDVIKAIGQGAFGKAYLAKGKSDSKHCVIKEINFEKMPIQEK-EASKKEVILLEKMKH-PNIVAFFNSFQENGRLFIVMEYCDGGDLMKRINRQRGVLFSEDQILGWFVQISLGLKHIHDRKILHRDIKAQNIFLSKNGMVAKLGDFGIA---RVLN-NSMELARTCIGTPYYLSPEICQNKPYNNKTDIWSLGCVLYELCTLKHPFEGNNLQQLVLKICQAHFAPISP-GFSRELHSLISQLFQVSPRDRPSINSIL 254
[Close]
BLAST of SMED30028687 vs. Ensembl Human
Match: PAK1 (p21 (RAC1) activated kinase 1 [Source:HGNC Symbol;Acc:HGNC:8590])

HSP 1 Score: 125.561 bits (314), Expect = 3.506e-29
Identity = 81/259 (31.27%), Postives = 140/259 (54.05%), Query Frame = -2 
Query:  277 LKKLGIGAFAKVKLCKNKLSGRVFALK---MPKNKNINAILNEISIFSTLKSSPSMILFHGIYLHSNKLCIAMEYISGKTLESVLKDENSLDYSLKLQFVFQILQQIKSLHDAGIIHRDISCNNIMIYKENQNAKLIDFGLSISVKGLNTDAIELSGKYGTPWYMAPELLTHEPYSNKIDIWSVGVVAVKIFSGERPYTYLNPTKFQAKIAKDKTIEL-DPQNFSKDVFDFLSPCFKSDPKERPTVDDLLSSK--MFQI 1035
             +K+G GA   V    +  +G+  A+K   + +      I+NEI +    K+ P+++ +   YL  ++L + MEY++G +L  V+  E  +D         + LQ ++ LH   +IHRDI  +NI++  +  + KL DFG    +     +  + S   GTP++MAPE++T + Y  K+DIWS+G++A+++  GE PY   NP +    IA + T EL +P+  S    DFL+ C + D ++R +  +LL  +   FQ+
Sbjct:  175 FEKIGQGASGTVYTAMDVATGQEVAIKQMNLQQQPKKELIINEILVMRENKN-PNIVNYLDSYLVGDELWVVMEYLAGGSLTDVVT-ETCMDEGQIAAVCRECLQALEFLHSNQVIHRDIKSDNILLGMDG-SVKLTDFGFCAQI---TPEQSKRSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMIEGEPPYLNENPLRALYLIATNGTPELQNPEKLSAIFRDFLNRCLEMDVEKRGSAKELLQVRKLRFQV 427
[Close]
BLAST of SMED30028687 vs. Ensembl Human
Match: STK24 (serine/threonine kinase 24 [Source:HGNC Symbol;Acc:HGNC:11403])

HSP 1 Score: 124.79 bits (312), Expect = 4.383e-29
Identity = 91/277 (32.85%), Postives = 143/277 (51.62%), Query Frame = -2 
Query:  229 LKKLGIGAFAKVKLCKNKLSGRVFALKM----PKNKNINAILNEISIFSTLKSSPSMILFHGIYLHSNKLCIAMEYISGKTLESVLKDENSLDYSLKLQFVFQILQQIKSLHDAGIIHRDISCNNIMIYKENQNAKLIDFGLSISVKGLNTDA-IELSGKYGTPWYMAPELLTHEPYSNKIDIWSVGVVAVKIFSGERPYTYLNPTKFQAKIAKDKTIELDPQNFSKDVFDFLSPCFKSDPKERPTVDDLLSSKMFQIN---RSWQISRISRTD*WR 1035
            L+K+G G+F +V    +  + +V A+K+         I  I  EI++ S    SP +  ++G YL   KL I MEY+ G +   +L +   LD +     + +IL+ +  LH    IHRDI   N+++  E+   KL DFG    V G  TD  I+ +   GTP++MAPE++    Y +K DIWS+G+ A+++  GE P++ L+P K    I K+    L+  N+SK + +F+  C   +P  RPT  +LL  K    N    S+    I R   W+
Sbjct:   27 LEKIGKGSFGEVFKGIDNRTQKVVAIKIIDLEEAEDEIEDIQQEITVLSQC-DSPYVTKYYGSYLKDTKLWIIMEYLGGGSALDLL-EPGPLDETQIATILREILKGLDYLHSEKKIHRDIKAANVLL-SEHGEVKLADFG----VAGQLTDTQIKRNTFVGTPFWMAPEVIKQSAYDSKADIWSLGITAIELARGEPPHSELHPMKVLFLIPKNNPPTLE-GNYSKPLKEFVEACLNKEPSFRPTAKELLKHKFILRNAKKTSYLTELIDRYKRWK 295
[Close]
BLAST of SMED30028687 vs. Ensembl Celegans
Match: cst-2 (Caenorhabditis STE20-like kinase [Source:UniProtKB/TrEMBL;Acc:Q304D8])

HSP 1 Score: 119.398 bits (298), Expect = 1.026e-27
Identity = 77/249 (30.92%), Postives = 129/249 (51.81%), Query Frame = -2 
Query:  310 EVLKKLGIGAFAKVKLCKNKLSGRVFALK-MPKNKNINAILNEISIFSTLKSSPSMILFHGIYLHSNKLCIAMEYISGKTLESVLKDENSLDYSLKLQFVFQ-ILQQIKSLHDAGIIHRDISCNNIMIYKENQNAKLIDFGLSISVKGLNTDAIELSGKY-GTPWYMAPELLTHEPYSNKIDIWSVGVVAVKIFSGERPYTYLNPTK--FQAKIAKDKTIELDPQNFSKDVFDFLSPCFKSDPKERPTV 1041
            +++ KLG G++  V    ++ SG V A+K +P + ++  I+ EISI    KS   ++ ++G Y   + L I MEY    ++  +++         ++  V +  L+ ++ LHD   IHRDI   NI++  +   AKL DFG    V G  TD +       GTP++MAPE++    Y  K DIWS+G+ A+++  G  PY+ ++P +  F        T +  P+ +S +  DF+  C    P+ER T 
Sbjct:   36 DIVGKLGEGSYGSVHKAIHRESGHVLAIKKVPVDTDLQEIIKEISIMQQCKSK-YVVKYYGSYFKHSDLWIVMEYCGAGSISDIMRARRKPLSEQEISAVLRDTLKGLQYLHDLKKIHRDIKAGNILLNTDGI-AKLADFG----VAGQLTDTMAKRNTVIGTPFWMAPEVIEEIGYDTKADIWSLGITAIEMAEGRPPYSDIHPMRAIFMIPTKPPPTFK-KPEEWSSEFNDFIRSCLIKKPEERKTA 277
[Close]
BLAST of SMED30028687 vs. Ensembl Celegans
Match: cst-1 (Serine/threonine-protein kinase cst-1 Serine/threonine-protein kinase cst-1 37kDa subunit Serine/threonine-protein kinase cst-1 18kDa subunit [Source:UniProtKB/Swiss-Prot;Acc:Q9NB31])

HSP 1 Score: 119.398 bits (298), Expect = 2.651e-27
Identity = 77/249 (30.92%), Postives = 129/249 (51.81%), Query Frame = -2 
Query:  310 EVLKKLGIGAFAKVKLCKNKLSGRVFALK-MPKNKNINAILNEISIFSTLKSSPSMILFHGIYLHSNKLCIAMEYISGKTLESVLKDENSLDYSLKLQFVFQ-ILQQIKSLHDAGIIHRDISCNNIMIYKENQNAKLIDFGLSISVKGLNTDAIELSGKY-GTPWYMAPELLTHEPYSNKIDIWSVGVVAVKIFSGERPYTYLNPTK--FQAKIAKDKTIELDPQNFSKDVFDFLSPCFKSDPKERPTV 1041
            +++ KLG G++  V    ++ SG V A+K +P + ++  I+ EISI    KS   ++ ++G Y   + L I MEY    ++  +++         ++  V +  L+ ++ LHD   IHRDI   NI++  +   AKL DFG    V G  TD +       GTP++MAPE++    Y  K DIWS+G+ A+++  G  PY+ ++P +  F        T +  P+ +S +  DF+  C    P+ER T 
Sbjct:   36 DIVGKLGEGSYGSVHKAIHRESGHVLAIKKVPVDTDLQEIIKEISIMQQCKSK-YVVKYYGSYFKHSDLWIVMEYCGAGSISDIMRARRKPLSEQEISAVLRDTLKGLQYLHDLKKIHRDIKAGNILLNTDGI-AKLADFG----VAGQLTDTMAKRNTVIGTPFWMAPEVIEEIGYDTKADIWSLGITAIEMAEGRPPYSDIHPMRAIFMIPTKPPPTFK-KPEEWSSEFNDFIRSCLIKKPEERKTA 277
[Close]
BLAST of SMED30028687 vs. Ensembl Celegans
Match: cst-1 (Serine/threonine-protein kinase cst-1 Serine/threonine-protein kinase cst-1 37kDa subunit Serine/threonine-protein kinase cst-1 18kDa subunit [Source:UniProtKB/Swiss-Prot;Acc:Q9NB31])

HSP 1 Score: 119.398 bits (298), Expect = 2.788e-27
Identity = 77/249 (30.92%), Postives = 129/249 (51.81%), Query Frame = -2 
Query:  310 EVLKKLGIGAFAKVKLCKNKLSGRVFALK-MPKNKNINAILNEISIFSTLKSSPSMILFHGIYLHSNKLCIAMEYISGKTLESVLKDENSLDYSLKLQFVFQ-ILQQIKSLHDAGIIHRDISCNNIMIYKENQNAKLIDFGLSISVKGLNTDAIELSGKY-GTPWYMAPELLTHEPYSNKIDIWSVGVVAVKIFSGERPYTYLNPTK--FQAKIAKDKTIELDPQNFSKDVFDFLSPCFKSDPKERPTV 1041
            +++ KLG G++  V    ++ SG V A+K +P + ++  I+ EISI    KS   ++ ++G Y   + L I MEY    ++  +++         ++  V +  L+ ++ LHD   IHRDI   NI++  +   AKL DFG    V G  TD +       GTP++MAPE++    Y  K DIWS+G+ A+++  G  PY+ ++P +  F        T +  P+ +S +  DF+  C    P+ER T 
Sbjct:   36 DIVGKLGEGSYGSVHKAIHRESGHVLAIKKVPVDTDLQEIIKEISIMQQCKSK-YVVKYYGSYFKHSDLWIVMEYCGAGSISDIMRARRKPLSEQEISAVLRDTLKGLQYLHDLKKIHRDIKAGNILLNTDGI-AKLADFG----VAGQLTDTMAKRNTVIGTPFWMAPEVIEEIGYDTKADIWSLGITAIEMAEGRPPYSDIHPMRAIFMIPTKPPPTFK-KPEEWSSEFNDFIRSCLIKKPEERKTA 277
[Close]
BLAST of SMED30028687 vs. Ensembl Celegans
Match: gck-1 (Germinal center kinase 1 [Source:UniProtKB/Swiss-Prot;Acc:H2L099])

HSP 1 Score: 120.553 bits (301), Expect = 3.847e-27
Identity = 79/250 (31.60%), Postives = 131/250 (52.40%), Query Frame = -2 
Query:  298 KKLGIGAFAKVKLCKNKLSGRVFALKM----PKNKNINAILNEISIFSTLKSSPSMILFHGIYLHSNKLCIAMEYISGKTLESVLKDENSLDYSLKLQFVFQILQQIKSLHDAGIIHRDISCNNIMIYKENQNAKLIDFGLSISVKGLNTDAIELSGKY-GTPWYMAPELLTHEPYSNKIDIWSVGVVAVKIFSGERPYTYLNPTKFQAKIAKDKTIELDPQNFSKDVFDFLSPCFKSDPKERPTVDDLL 1032
            +++G G+F +V    +  +GRV A+K+         I  I  EI + S   S   +  + G +L  +KL I MEY+ G +   + K    LD S     + +IL+ ++ LH    IHRDI   N+++  E+ + K+ DFG    V G  T+ ++    + G+P++MAPEL+    Y  K DIWS+G+ A+++ +GE P++ L+P +    I K+    L    +SK   +F+  C   DP+ RP+   LL
Sbjct:   18 ERIGRGSFGEVYKGIDNRTGRVVAIKIIDLEQAEDEIEDIQQEIQVLSQCDSQ-YVTKYFGSFLKGSKLWIIMEYLGGGSALDLTKS-GKLDESHIAVILREILKGLEYLHSERKIHRDIKAANVLV-SEHGDVKVADFG----VAGQLTETVKKRITFVGSPFWMAPELIKQSSYDYKADIWSLGITAIELANGEPPHSDLHPMRVLFLIPKNPPPVLQGSQWSKPFKEFVEMCLNKDPENRPSASTLL 260
[Close]
BLAST of SMED30028687 vs. Ensembl Celegans
Match: gck-1 (Germinal center kinase 1 [Source:UniProtKB/Swiss-Prot;Acc:H2L099])

HSP 1 Score: 120.168 bits (300), Expect = 4.253e-27
Identity = 79/250 (31.60%), Postives = 131/250 (52.40%), Query Frame = -2 
Query:  298 KKLGIGAFAKVKLCKNKLSGRVFALKM----PKNKNINAILNEISIFSTLKSSPSMILFHGIYLHSNKLCIAMEYISGKTLESVLKDENSLDYSLKLQFVFQILQQIKSLHDAGIIHRDISCNNIMIYKENQNAKLIDFGLSISVKGLNTDAIELSGKY-GTPWYMAPELLTHEPYSNKIDIWSVGVVAVKIFSGERPYTYLNPTKFQAKIAKDKTIELDPQNFSKDVFDFLSPCFKSDPKERPTVDDLL 1032
            +++G G+F +V    +  +GRV A+K+         I  I  EI + S   S   +  + G +L  +KL I MEY+ G +   + K    LD S     + +IL+ ++ LH    IHRDI   N+++  E+ + K+ DFG    V G  T+ ++    + G+P++MAPEL+    Y  K DIWS+G+ A+++ +GE P++ L+P +    I K+    L    +SK   +F+  C   DP+ RP+   LL
Sbjct:   23 ERIGRGSFGEVYKGIDNRTGRVVAIKIIDLEQAEDEIEDIQQEIQVLSQCDSQ-YVTKYFGSFLKGSKLWIIMEYLGGGSALDLTKS-GKLDESHIAVILREILKGLEYLHSERKIHRDIKAANVLV-SEHGDVKVADFG----VAGQLTETVKKRITFVGSPFWMAPELIKQSSYDYKADIWSLGITAIELANGEPPHSDLHPMRVLFLIPKNPPPVLQGSQWSKPFKEFVEMCLNKDPENRPSASTLL 265
[Close]
BLAST of SMED30028687 vs. Ensembl Fly
Match: Mekk1 (gene:FBgn0024329 transcript:FBtr0331353)

HSP 1 Score: 139.813 bits (351), Expect = 2.558e-32
Identity = 86/263 (32.70%), Postives = 139/263 (52.85%), Query Frame = -2 
Query:  271 KLGIGAFAKVKLCKNKLSGRVFALK----MP-KNKNINAILNEISIFSTLKSSPSMILFHGIYLHSNKLCIAMEYISGKTLESVLKDENSLDYSLKLQFVFQILQQIKSLHDAGIIHRDISCNNIMIYKENQNAKLIDFGLSISVKGLNTDAIELSGKYGTPWYMAPELLT---HEPYSNKIDIWSVGVVAVKIFSGERPYTYLNPTKFQA--KIAKDKTIELDPQNFSKDVFDFLSPCFKSDPKERPTVDDLLSSKMFQINR 1029
            K+G G F KV    N  +G + A+K     P + + +  +  E+ I   +K   +++ ++GI +H  +L I ME  S  TLES+++   +L  +L  +F  Q+L  +  LH  GI+HRDI   NI +   + + KL DFG ++ ++   T   EL G  GT  YMAPE+ T    + +    DIWSVG V V++ SG+RP+   + + FQ   K+   +  +  P++ S++  DF+  C + DPK R T  +LL     +  R
Sbjct: 1194 KIGQGRFGKVYTAVNNNTGELMAMKEIAIQPGETRALKNVAEELKILEGIKHK-NLVRYYGIEVHREELLIFMELCSEGTLESLVELTGNLPEALTRRFTAQLLSGVSELHKHGIVHRDIKTANIFLVDGSNSLKLGDFGSAVKIQAHTTVPGELQGYVGTQAYMAPEVFTKTNSDGHGRAADIWSVGCVVVEMASGKRPWAQFD-SNFQIMFKVGMGEKPQA-PESLSQEGHDFIDHCLQHDPKRRLTAVELLEHNFCKYGR 1453
[Close]
BLAST of SMED30028687 vs. Ensembl Fly
Match: Mekk1 (gene:FBgn0024329 transcript:FBtr0083684)

HSP 1 Score: 139.813 bits (351), Expect = 2.694e-32
Identity = 86/263 (32.70%), Postives = 139/263 (52.85%), Query Frame = -2 
Query:  271 KLGIGAFAKVKLCKNKLSGRVFALK----MP-KNKNINAILNEISIFSTLKSSPSMILFHGIYLHSNKLCIAMEYISGKTLESVLKDENSLDYSLKLQFVFQILQQIKSLHDAGIIHRDISCNNIMIYKENQNAKLIDFGLSISVKGLNTDAIELSGKYGTPWYMAPELLT---HEPYSNKIDIWSVGVVAVKIFSGERPYTYLNPTKFQA--KIAKDKTIELDPQNFSKDVFDFLSPCFKSDPKERPTVDDLLSSKMFQINR 1029
            K+G G F KV    N  +G + A+K     P + + +  +  E+ I   +K   +++ ++GI +H  +L I ME  S  TLES+++   +L  +L  +F  Q+L  +  LH  GI+HRDI   NI +   + + KL DFG ++ ++   T   EL G  GT  YMAPE+ T    + +    DIWSVG V V++ SG+RP+   + + FQ   K+   +  +  P++ S++  DF+  C + DPK R T  +LL     +  R
Sbjct: 1287 KIGQGRFGKVYTAVNNNTGELMAMKEIAIQPGETRALKNVAEELKILEGIKHK-NLVRYYGIEVHREELLIFMELCSEGTLESLVELTGNLPEALTRRFTAQLLSGVSELHKHGIVHRDIKTANIFLVDGSNSLKLGDFGSAVKIQAHTTVPGELQGYVGTQAYMAPEVFTKTNSDGHGRAADIWSVGCVVVEMASGKRPWAQFD-SNFQIMFKVGMGEKPQA-PESLSQEGHDFIDHCLQHDPKRRLTAVELLEHNFCKYGR 1546
[Close]
BLAST of SMED30028687 vs. Ensembl Fly
Match: GckIII (gene:FBgn0266465 transcript:FBtr0083399)

HSP 1 Score: 115.931 bits (289), Expect = 1.442e-25
Identity = 75/250 (30.00%), Postives = 131/250 (52.40%), Query Frame = -2 
Query:  298 KKLGIGAFAKVKLCKNKLSGRVFALKM----PKNKNINAILNEISIFSTLKSSPSMILFHGIYLHSNKLCIAMEYISGKTLESVLKDENSLDYSLKLQFVFQILQQIKSLHDAGIIHRDISCNNIMIYKENQNAKLIDFGLSISVKGLNTDAIELSGKY-GTPWYMAPELLTHEPYSNKIDIWSVGVVAVKIFSGERPYTYLNPTKFQAKIAKDKTIELDPQNFSKDVFDFLSPCFKSDPKERPTVDDLL 1032
            +++G G+F +V    +  + +V A+K+         I+ I  EI + S    SP +  ++G +L   KL I MEY+ G +   ++K  +  +  + +  + ++L+ +  LH    +HRDI   N+++  E  + KL DFG    V G  T+       + GTP++MAPE++    Y  K DIWS+G+ A+++  GE P + L+P +    I K+   +L   +++K   DF+  C   DP+ RPT  +LL
Sbjct:   17 ERIGKGSFGEVFKGIDNRTQQVVAIKIIDLEEAEDEIDDIQQEIMVLSQC-DSPYVTKYYGSFLKGTKLWIIMEYLGGGSALDLMKAGSFEEMHIGI-ILREVLKGLDYLHSERKLHRDIKAANVLL-SEQGDVKLADFG----VAGQLTNTTSKRNTFVGTPFWMAPEVIKQSQYDAKADIWSLGITAIELAKGEPPNSELHPMRVLFLIPKNNPPQLT-GSYTKSFKDFVEACLNKDPENRPTAKELL 258
[Close]
BLAST of SMED30028687 vs. Ensembl Fly
Match: Slik (gene:FBgn0035001 transcript:FBtr0332925)

HSP 1 Score: 117.087 bits (292), Expect = 1.716e-25
Identity = 83/269 (30.86%), Postives = 143/269 (53.16%), Query Frame = -2 
Query:  268 EVLKKLGIGAFAKVKLCKNKLSGRVFALKM---PKNKNINAILNEISIFSTLKSSPSMILFHGIYLHSNKLCIAMEYISGKTLESVLKDENSLDYSLKLQFVFQILQQ-IKSLHDAGIIHRDISCNNIMIYKENQNAKLIDFGLSISVKGLNTDAIELSGKY-GTPWYMAPELLTHE-----PYSNKIDIWSVGVVAVKIFSGERPYTYLNPTKFQAKIAKDKTIELD-PQNFSKDVFDFLSPCFKSDPKERPTVDDLLSSKMFQINRS 1041
            E++ +LG GAF KV   ++K   R  A KM      +N++  + EI I S +K  P+++  +  +   +KL + +EY  G  L+S++ +        ++ +V + + + +  LH   +IHRD+   N+++  E    KL DFG+S      N   ++    + GTP++MAPEL+  E     PY +K+DIWS+G+  +++   E P + ++P +   KI K +  +L+ P  +SK+  DFL      DP+ RPT D L+      INR+
Sbjct:   38 EMVGELGDGAFGKVYKAQHKEQKRFAAAKMCQLEDEENLSDHMVEIDILSEIKH-PNIVELYEAFSIDDKLWMLIEYCDGGALDSIMVELEKPLTEPQIAYVCKHMTEGLTFLHRNKVIHRDLKAGNVLLTMEG-GVKLADFGVSAK----NKHTMQKHDTFIGTPYWMAPELVLCETFRDNPYDHKVDIWSLGITLIELAQMEPPNSEMSPMRVLLKIQKSEPPKLEQPSRWSKEFNDFLKKSLVKDPQVRPTTDVLMQHAF--INRN 298
[Close]
BLAST of SMED30028687 vs. Ensembl Fly
Match: Slik (gene:FBgn0035001 transcript:FBtr0072363)

HSP 1 Score: 117.087 bits (292), Expect = 1.919e-25
Identity = 83/269 (30.86%), Postives = 143/269 (53.16%), Query Frame = -2 
Query:  268 EVLKKLGIGAFAKVKLCKNKLSGRVFALKM---PKNKNINAILNEISIFSTLKSSPSMILFHGIYLHSNKLCIAMEYISGKTLESVLKDENSLDYSLKLQFVFQILQQ-IKSLHDAGIIHRDISCNNIMIYKENQNAKLIDFGLSISVKGLNTDAIELSGKY-GTPWYMAPELLTHE-----PYSNKIDIWSVGVVAVKIFSGERPYTYLNPTKFQAKIAKDKTIELD-PQNFSKDVFDFLSPCFKSDPKERPTVDDLLSSKMFQINRS 1041
            E++ +LG GAF KV   ++K   R  A KM      +N++  + EI I S +K  P+++  +  +   +KL + +EY  G  L+S++ +        ++ +V + + + +  LH   +IHRD+   N+++  E    KL DFG+S      N   ++    + GTP++MAPEL+  E     PY +K+DIWS+G+  +++   E P + ++P +   KI K +  +L+ P  +SK+  DFL      DP+ RPT D L+      INR+
Sbjct:   38 EMVGELGDGAFGKVYKAQHKEQKRFAAAKMCQLEDEENLSDHMVEIDILSEIKH-PNIVELYEAFSIDDKLWMLIEYCDGGALDSIMVELEKPLTEPQIAYVCKHMTEGLTFLHRNKVIHRDLKAGNVLLTMEG-GVKLADFGVSAK----NKHTMQKHDTFIGTPYWMAPELVLCETFRDNPYDHKVDIWSLGITLIELAQMEPPNSEMSPMRVLLKIQKSEPPKLEQPSRWSKEFNDFLKKSLVKDPQVRPTTDVLMQHAF--INRN 298
[Close]
BLAST of SMED30028687 vs. Ensembl Zebrafish
Match: dapk2a (death-associated protein kinase 2a [Source:ZFIN;Acc:ZDB-GENE-080402-8])

HSP 1 Score: 127.102 bits (318), Expect = 1.096e-29
Identity = 88/279 (31.54%), Postives = 139/279 (49.82%), Query Frame = -2 
Query:  265 DNIEVLKKLGIGAFAKVKLCKNKLSGRVFALKMPKNKNINA---------ILNEISIFSTLKSSPSMILFHGIYLHSNKLCIAMEYISGKTLESVLKDENSLDYSLKLQFVFQILQQIKSLHDAGIIHRDISCNNIMIYKENQ---NAKLIDFGLSISVKGLNTDAIELSGKYGTPWYMAPELLTHEPYSNKIDIWSVGVVAVKIFSGERPYTYLNPTKFQAKIAKDKTI--ELDPQNF---SKDVFDFLSPCFKSDPKERPTVDDLLSSKMFQINRSW 1050
            D  E+ ++LG G FA VK C+ K SGR FA K  K +  NA         I  E++I   +   P++++ H ++ +   + + +E +SG  L   L  + SL      QF+ QIL+ +  LH   I H D+   NIM+  +N      KLIDFGL+  +     + +E    +GTP ++APE++ +EP   + D+WSVGV+   + SG  P  +L  TK Q  +     +  E D + F   S+   +F+    + D K+R T+ D L       N +W
Sbjct:   11 DFFEIGEELGSGQFAIVKQCREKSSGRDFAAKFIKKRQSNASRRGVLREEIEREVNILQQI-HHPNIVMLHDVFENKTDVVLILELVSGGELFDFLAQKESLSEEEATQFIKQILEGVHYLHSRNIAHFDLKPENIMLLDKNAPLPRIKLIDFGLAHKI----AEGVEFKNIFGTPEFVAPEIVNYEPLGLEADMWSVGVITYILLSGASP--FLGETK-QDTLGNISAMNYEFDDEFFGHTSELAKNFIRQLLEKDTKKRLTIQDAL-------NHAW 274
[Close]
BLAST of SMED30028687 vs. Ensembl Zebrafish
Match: stk24b (serine/threonine kinase 24b (STE20 homolog, yeast) [Source:ZFIN;Acc:ZDB-GENE-040426-2841])

HSP 1 Score: 124.405 bits (311), Expect = 3.198e-29
Identity = 85/255 (33.33%), Postives = 137/255 (53.73%), Query Frame = -2 
Query:  286 LKKLGIGAFAKVKLCKNKLSGRVFALKM----PKNKNINAILNEISIFSTLKSSPSMILFHGIYLHSNKLCIAMEYISGKTLESVLKDENSLDYSLKLQFVFQILQQIKSLHDAGIIHRDISCNNIMIYKENQNAKLIDFGLSISVKGLNTDA-IELSGKYGTPWYMAPELLTHEPYSNKIDIWSVGVVAVKIFSGERPYTYLNPTKFQAKIAKDKTIELDPQNFSKDVFDFLSPCFKSDPKERPTVDDLLSSKM 1035
            L+++G G+F +V    +  + +V A+K+         I  I  EI++ S    SP +  ++G YL   KL I MEY+ G +   +L +  SLD +     + +IL+ ++ LH    IHRDI   N+++  E    KL DFG    V G  TD  I+ +   GTP++MAPE++    Y +K DIWS+G+ A+++  GE P++ L+P K    I K+    L+  N+ K + +F+  C   +P  RPT  +LL  K+
Sbjct:   15 LERIGKGSFGEVFKGIDNRTQKVVAIKIIDLEEAEDEIEDIQQEITVLSQC-DSPFVTKYYGSYLKDTKLWIIMEYLGGGSALDLL-EPGSLDETQIATILREILKGLEYLHSEKKIHRDIKAANVLL-SEQGEVKLADFG----VAGQLTDTQIKRNTFVGTPFWMAPEVIKQSAYDSKADIWSLGITAIELAKGEPPHSDLHPMKVLFLIPKNNPPTLE-GNYCKPLKEFVEACLNKEPSFRPTAKELLKHKL 261
[Close]
BLAST of SMED30028687 vs. Ensembl Zebrafish
Match: stk24b (serine/threonine kinase 24b (STE20 homolog, yeast) [Source:ZFIN;Acc:ZDB-GENE-040426-2841])

HSP 1 Score: 124.405 bits (311), Expect = 3.881e-29
Identity = 85/256 (33.20%), Postives = 137/256 (53.52%), Query Frame = -2 
Query:  283 LKKLGIGAFAKVKLCKNKLSGRVFALKM----PKNKNINAILNEISIFSTLKSSPSMILFHGIYLHSNKLCIAMEYISGKTLESVLKDENSLDYSLKLQFVFQILQQIKSLHDAGIIHRDISCNNIMIYKENQNAKLIDFGLSISVKGLNTDA-IELSGKYGTPWYMAPELLTHEPYSNKIDIWSVGVVAVKIFSGERPYTYLNPTKFQAKIAKDKTIELDPQNFSKDVFDFLSPCFKSDPKERPTVDDLLSSKMF 1035
            L+++G G+F +V    +  + +V A+K+         I  I  EI++ S    SP +  ++G YL   KL I MEY+ G +   +L +  SLD +     + +IL+ ++ LH    IHRDI   N+++  E    KL DFG    V G  TD  I+ +   GTP++MAPE++    Y +K DIWS+G+ A+++  GE P++ L+P K    I K+    L+  N+ K + +F+  C   +P  RPT  +LL  K+ 
Sbjct:   27 LERIGKGSFGEVFKGIDNRTQKVVAIKIIDLEEAEDEIEDIQQEITVLSQC-DSPFVTKYYGSYLKDTKLWIIMEYLGGGSALDLL-EPGSLDETQIATILREILKGLEYLHSEKKIHRDIKAANVLL-SEQGEVKLADFG----VAGQLTDTQIKRNTFVGTPFWMAPEVIKQSAYDSKADIWSLGITAIELAKGEPPHSDLHPMKVLFLIPKNNPPTLE-GNYCKPLKEFVEACLNKEPSFRPTAKELLKHKLI 274
[Close]
BLAST of SMED30028687 vs. Ensembl Zebrafish
Match: pak2a (p21 protein (Cdc42/Rac)-activated kinase 2a [Source:ZFIN;Acc:ZDB-GENE-021011-2])

HSP 1 Score: 125.176 bits (313), Expect = 6.805e-29
Identity = 80/258 (31.01%), Postives = 140/258 (54.26%), Query Frame = -2 
Query:  271 KKLGIGAFAKVKLCKNKLSGRVFALK---MPKNKNINAILNEISIFSTLKSSPSMILFHGIYLHSNKLCIAMEYISGKTLESVLKDENSLDYSLKLQFVFQILQQIKSLHDAGIIHRDISCNNIMIYKENQNAKLIDFGLSISVKGLNTDAIELSGKYGTPWYMAPELLTHEPYSNKIDIWSVGVVAVKIFSGERPYTYLNPTKFQAKIAKDKTIEL-DPQNFSKDVFDFLSPCFKSDPKERPTVDDLLSSKMFQINR 1032
            +K+G GA   V    +  +G+  A+K   + K      I+NEI +   LK+ P+++ F   +L  ++L + MEY++G +L  V+  E  +D +       + LQ ++ LH   +IHRDI  +N+++  +  + KL DFG    +     +  + S   GTP++MAPE++T + Y  K+DIWS+G++A+++  GE PY   NP +    IA + T EL +P+  S    DFL+ C + D ++R    +LL     ++ +
Sbjct:  246 EKIGQGASGTVYTAIDVATGQEVAIKQINLQKQPKKELIINEILVMKELKN-PNIVNFLDSFLVGDELFVVMEYLAGGSLTDVVT-ETCMDEAQIAAVCRECLQALEFLHANQVIHRDIKSDNVLLGMDG-SVKLTDFGFCAQI---TPEQSKRSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMVEGEPPYLNENPLRALYLIATNGTPELQNPEKLSPIFRDFLNRCLEMDVEKRGGGKELLQHPFLKLAK 497
[Close]
BLAST of SMED30028687 vs. Ensembl Zebrafish
Match: pak2a (p21 protein (Cdc42/Rac)-activated kinase 2a [Source:ZFIN;Acc:ZDB-GENE-021011-2])

HSP 1 Score: 125.176 bits (313), Expect = 6.805e-29
Identity = 80/258 (31.01%), Postives = 140/258 (54.26%), Query Frame = -2 
Query:  271 KKLGIGAFAKVKLCKNKLSGRVFALK---MPKNKNINAILNEISIFSTLKSSPSMILFHGIYLHSNKLCIAMEYISGKTLESVLKDENSLDYSLKLQFVFQILQQIKSLHDAGIIHRDISCNNIMIYKENQNAKLIDFGLSISVKGLNTDAIELSGKYGTPWYMAPELLTHEPYSNKIDIWSVGVVAVKIFSGERPYTYLNPTKFQAKIAKDKTIEL-DPQNFSKDVFDFLSPCFKSDPKERPTVDDLLSSKMFQINR 1032
            +K+G GA   V    +  +G+  A+K   + K      I+NEI +   LK+ P+++ F   +L  ++L + MEY++G +L  V+  E  +D +       + LQ ++ LH   +IHRDI  +N+++  +  + KL DFG    +     +  + S   GTP++MAPE++T + Y  K+DIWS+G++A+++  GE PY   NP +    IA + T EL +P+  S    DFL+ C + D ++R    +LL     ++ +
Sbjct:  246 EKIGQGASGTVYTAIDVATGQEVAIKQINLQKQPKKELIINEILVMKELKN-PNIVNFLDSFLVGDELFVVMEYLAGGSLTDVVT-ETCMDEAQIAAVCRECLQALEFLHANQVIHRDIKSDNVLLGMDG-SVKLTDFGFCAQI---TPEQSKRSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMVEGEPPYLNENPLRALYLIATNGTPELQNPEKLSPIFRDFLNRCLEMDVEKRGGGKELLQHPFLKLAK 497
[Close]
BLAST of SMED30028687 vs. Ensembl Xenopus
Match: stk25 (serine/threonine kinase 25 [Source:NCBI gene;Acc:548355])

HSP 1 Score: 129.413 bits (324), Expect = 6.563e-31
Identity = 94/293 (32.08%), Postives = 145/293 (49.49%), Query Frame = -2 
Query:  181 LKKLGIGAFAKVKLCKNKLSGRVFALKM----PKNKNINAILNEISIFSTLKSSPSMILFHGIYLHSNKLCIAMEYISGKTLESVLKDENSLDYSLKLQFVFQILQQIKSLHDAGIIHRDISCNNIMIYKENQNAKLIDFGLSISVKGLNTDA-IELSGKYGTPWYMAPELLTHEPYSNKIDIWSVGVVAVKIFSGERPYTYLNPTKFQAKIAKDKTIELDPQNFSKDVFDFLSPCFKSDPKERPTVDDLLSSKM---FQINRSWQISRISRTD*WRKAAFICSGSDHEGIIN 1035
            L+++G G+F +V       S  V A+K+         I  I  EI++ S    SP +  ++G YL  +KL I MEY+ G +   +LK    L+ +     + +IL+ +  LH    IHRDI   N+++  E  + KL DFG    V G  TD  I+ +   GTP++MAPE++    Y  K DIWS+G+ A+++  GE PY+ L+P +    I K+    L  Q +SK   DF+  C   DP+ RPT  +LL  +    +    S+ +  + R   W+        S  E  IN
Sbjct:   22 LERIGKGSFGEVYKGIENRSKEVVAIKIIDLEEAEDEIEDIQQEITVLSQC-DSPYITRYYGSYLKGSKLWIIMEYLGGGSALDLLKP-GPLEEAYIATILREILKGLDYLHSERKIHRDIKAANVLL-SEQGDVKLADFG----VAGQLTDTQIKRNTFVGTPFWMAPEVIKQSAYDFKADIWSLGITAIELAKGEPPYSDLHPMRVLFLIPKNNPPSLQGQ-YSKPFKDFVEACLNKDPRSRPTARELLKHRFILRYTKKTSFLVELVERHKRWKSQGHREDSSSDESDIN 306
[Close]
BLAST of SMED30028687 vs. Ensembl Xenopus
Match: stk25 (serine/threonine kinase 25 [Source:NCBI gene;Acc:548355])

HSP 1 Score: 127.487 bits (319), Expect = 1.899e-30
Identity = 87/255 (34.12%), Postives = 133/255 (52.16%), Query Frame = -2 
Query:  286 LKKLGIGAFAKVKLCKNKLSGRVFALKM----PKNKNINAILNEISIFSTLKSSPSMILFHGIYLHSNKLCIAMEYISGKTLESVLKDENSLDYSLKLQFVFQILQQIKSLHDAGIIHRDISCNNIMIYKENQNAKLIDFGLSISVKGLNTDA-IELSGKYGTPWYMAPELLTHEPYSNKIDIWSVGVVAVKIFSGERPYTYLNPTKFQAKIAKDKTIELDPQNFSKDVFDFLSPCFKSDPKERPTVDDLLSSKM 1035
            L+++G G+F +V       S  V A+K+         I  I  EI++ S    SP +  ++G YL  +KL I MEY+ G +   +LK    L+ +     + +IL+ +  LH    IHRDI   N+++  E  + KL DFG    V G  TD  I+ +   GTP++MAPE++    Y  K DIWS+G+ A+++  GE PY+ L+P +    I K+    L  Q +SK   DF+  C   DP+ RPT  +LL  + 
Sbjct:   10 LERIGKGSFGEVYKGIENRSKEVVAIKIIDLEEAEDEIEDIQQEITVLSQC-DSPYITRYYGSYLKGSKLWIIMEYLGGGSALDLLKP-GPLEEAYIATILREILKGLDYLHSERKIHRDIKAANVLL-SEQGDVKLADFG----VAGQLTDTQIKRNTFVGTPFWMAPEVIKQSAYDFKADIWSLGITAIELAKGEPPYSDLHPMRVLFLIPKNNPPSLQGQ-YSKPFKDFVEACLNKDPRSRPTARELLKHRF 256
[Close]
BLAST of SMED30028687 vs. Ensembl Xenopus
Match: stk25 (serine/threonine kinase 25 [Source:NCBI gene;Acc:548355])

HSP 1 Score: 127.487 bits (319), Expect = 2.768e-30
Identity = 87/254 (34.25%), Postives = 133/254 (52.36%), Query Frame = -2 
Query:  289 LKKLGIGAFAKVKLCKNKLSGRVFALKM----PKNKNINAILNEISIFSTLKSSPSMILFHGIYLHSNKLCIAMEYISGKTLESVLKDENSLDYSLKLQFVFQILQQIKSLHDAGIIHRDISCNNIMIYKENQNAKLIDFGLSISVKGLNTDA-IELSGKYGTPWYMAPELLTHEPYSNKIDIWSVGVVAVKIFSGERPYTYLNPTKFQAKIAKDKTIELDPQNFSKDVFDFLSPCFKSDPKERPTVDDLLSSK 1035
            L+++G G+F +V       S  V A+K+         I  I  EI++ S    SP +  ++G YL  +KL I MEY+ G +   +LK    L+ +     + +IL+ +  LH    IHRDI   N+++  E  + KL DFG    V G  TD  I+ +   GTP++MAPE++    Y  K DIWS+G+ A+++  GE PY+ L+P +    I K+    L  Q +SK   DF+  C   DP+ RPT  +LL  +
Sbjct:   10 LERIGKGSFGEVYKGIENRSKEVVAIKIIDLEEAEDEIEDIQQEITVLSQC-DSPYITRYYGSYLKGSKLWIIMEYLGGGSALDLLKP-GPLEEAYIATILREILKGLDYLHSERKIHRDIKAANVLL-SEQGDVKLADFG----VAGQLTDTQIKRNTFVGTPFWMAPEVIKQSAYDFKADIWSLGITAIELAKGEPPYSDLHPMRVLFLIPKNNPPSLQGQ-YSKPFKDFVEACLNKDPRSRPTARELLKHR 255
[Close]
BLAST of SMED30028687 vs. Ensembl Xenopus
Match: stk25 (serine/threonine kinase 25 [Source:NCBI gene;Acc:548355])

HSP 1 Score: 127.487 bits (319), Expect = 3.006e-30
Identity = 87/254 (34.25%), Postives = 133/254 (52.36%), Query Frame = -2 
Query:  289 LKKLGIGAFAKVKLCKNKLSGRVFALKM----PKNKNINAILNEISIFSTLKSSPSMILFHGIYLHSNKLCIAMEYISGKTLESVLKDENSLDYSLKLQFVFQILQQIKSLHDAGIIHRDISCNNIMIYKENQNAKLIDFGLSISVKGLNTDA-IELSGKYGTPWYMAPELLTHEPYSNKIDIWSVGVVAVKIFSGERPYTYLNPTKFQAKIAKDKTIELDPQNFSKDVFDFLSPCFKSDPKERPTVDDLLSSK 1035
            L+++G G+F +V       S  V A+K+         I  I  EI++ S    SP +  ++G YL  +KL I MEY+ G +   +LK    L+ +     + +IL+ +  LH    IHRDI   N+++  E  + KL DFG    V G  TD  I+ +   GTP++MAPE++    Y  K DIWS+G+ A+++  GE PY+ L+P +    I K+    L  Q +SK   DF+  C   DP+ RPT  +LL  +
Sbjct:   10 LERIGKGSFGEVYKGIENRSKEVVAIKIIDLEEAEDEIEDIQQEITVLSQC-DSPYITRYYGSYLKGSKLWIIMEYLGGGSALDLLKP-GPLEEAYIATILREILKGLDYLHSERKIHRDIKAANVLL-SEQGDVKLADFG----VAGQLTDTQIKRNTFVGTPFWMAPEVIKQSAYDFKADIWSLGITAIELAKGEPPYSDLHPMRVLFLIPKNNPPSLQGQ-YSKPFKDFVEACLNKDPRSRPTARELLKHR 255
[Close]
BLAST of SMED30028687 vs. Ensembl Xenopus
Match: slc39a7 (solute carrier family 39 member 7 [Source:Xenbase;Acc:XB-GENE-492963])

HSP 1 Score: 123.635 bits (309), Expect = 9.482e-29
Identity = 85/254 (33.46%), Postives = 136/254 (53.54%), Query Frame = -2 
Query:  289 LKKLGIGAFAKVKLCKNKLSGRVFALKM----PKNKNINAILNEISIFSTLKSSPSMILFHGIYLHSNKLCIAMEYISGKTLESVLKDENSLDYSLKLQFVFQILQQIKSLHDAGIIHRDISCNNIMIYKENQNAKLIDFGLSISVKGLNTDA-IELSGKYGTPWYMAPELLTHEPYSNKIDIWSVGVVAVKIFSGERPYTYLNPTKFQAKIAKDKTIELDPQNFSKDVFDFLSPCFKSDPKERPTVDDLLSSK 1035
            L+K+G G+F +V    +  + +V A+K+         I  I  EI++ S    SP +  ++G YL   KL I MEY+ G +   +L +   LD +     + +IL+ +  LH    IHRDI   N+++  E+   KL DFG    V G  TD  I+ +   GTP++MAPE++    Y +K DIWS+G+ A+++  GE P++ L+P K    I K+    L+  N+SK + +F+  C   +P  RP+  +LL  K
Sbjct:   27 LEKIGKGSFGEVFKGIDNRTQKVVAIKIIDLEEAEDEIEDIQQEITVLSQC-DSPYVTKYYGSYLKDTKLWIIMEYLGGGSALDLL-EPGPLDETQIATILREILKGLDYLHSEKKIHRDIKAANVLL-SEHGEVKLADFG----VAGQLTDTQIKRNTFVGTPFWMAPEVIKQSAYDSKADIWSLGITAIELAKGEPPHSELHPMKVLFLIPKNNPPTLE-GNYSKGLKEFVEACLNKEPSFRPSAKELLKHK 272
[Close]
BLAST of SMED30028687 vs. Ensembl Mouse
Match: Pak2 (p21 (RAC1) activated kinase 2 [Source:MGI Symbol;Acc:MGI:1339984])

HSP 1 Score: 129.413 bits (324), Expect = 3.571e-30
Identity = 82/258 (31.78%), Postives = 140/258 (54.26%), Query Frame = -2 
Query:  271 KKLGIGAFAKVKLCKNKLSGRVFALK---MPKNKNINAILNEISIFSTLKSSPSMILFHGIYLHSNKLCIAMEYISGKTLESVLKDENSLDYSLKLQFVFQILQQIKSLHDAGIIHRDISCNNIMIYKENQNAKLIDFGLSISVKGLNTDAIELSGKYGTPWYMAPELLTHEPYSNKIDIWSVGVVAVKIFSGERPYTYLNPTKFQAKIAKDKTIEL-DPQNFSKDVFDFLSPCFKSDPKERPTVDDLLSSKMFQINR 1032
            +K+G GA   V    +   G+  A+K   + K      I+NEI +   LK+ P+++ F   YL  ++L + MEY++G +L  V+  E  +D +       + LQ ++ LH   +IHRDI  +N+++  E  + KL DFG    +     +  + S   GTP++MAPE++T + Y  K+DIWS+G++A+++  GE PY   NP +    IA + T EL +P+  S    DFL+ C + D ++R +  +LL     ++ +
Sbjct:  253 EKIGQGASGTVFTATDVALGQEVAIKQINLQKQPKKELIINEILVMKELKN-PNIVNFLDSYLVGDELFVVMEYLAGGSLTDVVT-ETCMDEAQIAAVCRECLQALEFLHANQVIHRDIKSDNVLLGMEG-SVKLTDFGFCAQI---TPEQSKRSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMVEGEPPYLNENPLRALYLIATNGTPELQNPEKLSPIFRDFLNRCLEMDVEKRGSAKELLQHPFLKLAK 504
[Close]
BLAST of SMED30028687 vs. Ensembl Mouse
Match: Nek5 (NIMA (never in mitosis gene a)-related expressed kinase 5 [Source:MGI Symbol;Acc:MGI:2142824])

HSP 1 Score: 128.642 bits (322), Expect = 1.317e-29
Identity = 83/256 (32.42%), Postives = 138/256 (53.91%), Query Frame = -2 
Query:  298 MDNIEVLKKLGIGAFAKVKLCKNKLSGRVFALK-MPKNKNINAILNEISIFSTLKSSPSMILFHGIYLHSNKLCIAMEYISGKTLESVLKDENSLDYSLK--LQFVFQILQQIKSLHDAGIIHRDISCNNIMIYKENQNAKLIDFGLSISVKGLNTDAIELSGK-YGTPWYMAPELLTHEPYSNKIDIWSVGVVAVKIFSGERPYTYLNPTKFQAKIAKDKTIELDPQNFSKDVFDFLSPCFKSDPKERPTVDDLL 1053
            MDN  ++K +G G F KV L K+K       +K +   K   A  NE+ + + ++  P+++ F   +  + +L I MEY  G  L   ++ +  + +S    L +  QI   +K +HD  I+HRDI   NI + K    AKL DFG   + + LN D++EL+    GTP+Y++PE+  + PY+NK DIWS+G V  ++ + + P+   N      KI + +   + P +FS+D+   +   F+  P++RP+V  LL
Sbjct:    1 MDNFHLIKIIGEGTFGKVYLAKDKSESSHCVIKEISLTKEKEASKNEVILLARMEH-PNIVTFFSSFQENGRLFIVMEYCDGGDLMQRIQRQRGVMFSEDQILCWFVQISLGLKHIHDRKILHRDIKSQNIFLSKNGMVAKLGDFG---TARTLN-DSMELAQTCAGTPYYLSPEICQNRPYNNKTDIWSLGCVLYELCTLKHPFESNNFHHLVLKICQGRVAPISP-HFSRDLQSLIPQLFRVSPQDRPSVTSLL 250
[Close]
BLAST of SMED30028687 vs. Ensembl Mouse
Match: Nek5 (NIMA (never in mitosis gene a)-related expressed kinase 5 [Source:MGI Symbol;Acc:MGI:2142824])

HSP 1 Score: 128.257 bits (321), Expect = 1.884e-29
Identity = 83/256 (32.42%), Postives = 138/256 (53.91%), Query Frame = -2 
Query:  298 MDNIEVLKKLGIGAFAKVKLCKNKLSGRVFALK-MPKNKNINAILNEISIFSTLKSSPSMILFHGIYLHSNKLCIAMEYISGKTLESVLKDENSLDYSLK--LQFVFQILQQIKSLHDAGIIHRDISCNNIMIYKENQNAKLIDFGLSISVKGLNTDAIELSGK-YGTPWYMAPELLTHEPYSNKIDIWSVGVVAVKIFSGERPYTYLNPTKFQAKIAKDKTIELDPQNFSKDVFDFLSPCFKSDPKERPTVDDLL 1053
            MDN  ++K +G G F KV L K+K       +K +   K   A  NE+ + + ++  P+++ F   +  + +L I MEY  G  L   ++ +  + +S    L +  QI   +K +HD  I+HRDI   NI + K    AKL DFG   + + LN D++EL+    GTP+Y++PE+  + PY+NK DIWS+G V  ++ + + P+   N      KI + +   + P +FS+D+   +   F+  P++RP+V  LL
Sbjct:    1 MDNFHLIKIIGEGTFGKVYLAKDKSESSHCVIKEISLTKEKEASKNEVILLARMEH-PNIVTFFSSFQENGRLFIVMEYCDGGDLMQRIQRQRGVMFSEDQILCWFVQISLGLKHIHDRKILHRDIKSQNIFLSKNGMVAKLGDFG---TARTLN-DSMELAQTCAGTPYYLSPEICQNRPYNNKTDIWSLGCVLYELCTLKHPFESNNFHHLVLKICQGRVAPISP-HFSRDLQSLIPQLFRVSPQDRPSVTSLL 250
[Close]
BLAST of SMED30028687 vs. Ensembl Mouse
Match: Pak1 (p21 (RAC1) activated kinase 1 [Source:MGI Symbol;Acc:MGI:1339975])

HSP 1 Score: 125.946 bits (315), Expect = 5.059e-29
Identity = 80/259 (30.89%), Postives = 140/259 (54.05%), Query Frame = -2 
Query:  271 LKKLGIGAFAKVKLCKNKLSGRVFALK---MPKNKNINAILNEISIFSTLKSSPSMILFHGIYLHSNKLCIAMEYISGKTLESVLKDENSLDYSLKLQFVFQILQQIKSLHDAGIIHRDISCNNIMIYKENQNAKLIDFGLSISVKGLNTDAIELSGKYGTPWYMAPELLTHEPYSNKIDIWSVGVVAVKIFSGERPYTYLNPTKFQAKIAKDKTIEL-DPQNFSKDVFDFLSPCFKSDPKERPTVDDLLSSKMFQINR 1035
             +K+G GA   V    +  +G+  A+K   + +      I+NEI +    K+ P+++ +   YL  ++L + MEY++G +L  V+  E  +D         + LQ ++ LH   +IHRDI  +NI++  +  + KL DFG    +     +  + S   GTP++MAPE++T + Y  K+DIWS+G++A+++  GE PY   NP +    IA + T EL +P+  S    DFL+ C + D ++R +  +LL  +  +I +
Sbjct:  272 FEKIGQGASGTVYTAMDVATGQEVAIKQMNLQQQPKKELIINEILVMRENKN-PNIVNYLDSYLVGDELWVVMEYLAGGSLTDVVT-ETCMDEGQIAAVCRECLQALEFLHSNQVIHRDIKSDNILLGMDG-SVKLTDFGFCAQI---TPEQSKRSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMIEGEPPYLNENPLRALYLIATNGTPELQNPEKLSAIFRDFLNRCLEMDVEKRGSAKELLQHQFLKIAK 524
[Close]
BLAST of SMED30028687 vs. Ensembl Mouse
Match: Pak1 (p21 (RAC1) activated kinase 1 [Source:MGI Symbol;Acc:MGI:1339975])

HSP 1 Score: 125.946 bits (315), Expect = 5.059e-29
Identity = 80/259 (30.89%), Postives = 140/259 (54.05%), Query Frame = -2 
Query:  271 LKKLGIGAFAKVKLCKNKLSGRVFALK---MPKNKNINAILNEISIFSTLKSSPSMILFHGIYLHSNKLCIAMEYISGKTLESVLKDENSLDYSLKLQFVFQILQQIKSLHDAGIIHRDISCNNIMIYKENQNAKLIDFGLSISVKGLNTDAIELSGKYGTPWYMAPELLTHEPYSNKIDIWSVGVVAVKIFSGERPYTYLNPTKFQAKIAKDKTIEL-DPQNFSKDVFDFLSPCFKSDPKERPTVDDLLSSKMFQINR 1035
             +K+G GA   V    +  +G+  A+K   + +      I+NEI +    K+ P+++ +   YL  ++L + MEY++G +L  V+  E  +D         + LQ ++ LH   +IHRDI  +NI++  +  + KL DFG    +     +  + S   GTP++MAPE++T + Y  K+DIWS+G++A+++  GE PY   NP +    IA + T EL +P+  S    DFL+ C + D ++R +  +LL  +  +I +
Sbjct:  272 FEKIGQGASGTVYTAMDVATGQEVAIKQMNLQQQPKKELIINEILVMRENKN-PNIVNYLDSYLVGDELWVVMEYLAGGSLTDVVT-ETCMDEGQIAAVCRECLQALEFLHSNQVIHRDIKSDNILLGMDG-SVKLTDFGFCAQI---TPEQSKRSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMIEGEPPYLNENPLRALYLIATNGTPELQNPEKLSAIFRDFLNRCLEMDVEKRGSAKELLQHQFLKIAK 524
[Close]
BLAST of SMED30028687 vs. UniProt/SwissProt
Match: sp|P38692|KIC1_YEAST (Serine/threonine-protein kinase KIC1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=KIC1 PE=1 SV=1)

HSP 1 Score: 133.265 bits (334), Expect = 1.735e-29
Identity = 82/262 (31.30%), Postives = 138/262 (52.67%), Query Frame = -2 
Query:  256 LGIGAFAKVKLCKNKLSGRVFALKM----PKNKNINAILNEISIFSTLKSSPSMILFHGIYLHSNKLCIAMEYISGKTLESVLKDENSLDYSLKLQFVFQILQQIKSLHDAGIIHRDISCNNIMIYKENQNAKLIDFGLSISVKGLNTDAIELSGKYGTPWYMAPELLTHEPY-SNKIDIWSVGVVAVKIFSGERPYTYLNPTKFQAKIAKDKTIELDPQNFSKDVFDFLSPCFKSDPKERPTVDDLLSSKMFQINRSWQIS 1026
            +G G F  V    N  +GRV+A+K+      +  +  +  EI   ++LK   ++  ++G YL    L I ME+ +G +L S+L+    +D       + ++L  +K +H   +IHRDI   N++I  E  N KL DFG++  V   N  ++      GTP++MAPE++    Y   K+DIWS+G+   +I +G  PY  +   +    I K K   L+ +++S  + +F++ C   DPKER + DDLL SK  + +++   S
Sbjct:   29 IGRGKFGVVYKGYNVKTGRVYAIKVLNLDSDSDEVEDVQREIQFLASLKQISNITRYYGSYLKDTSLWIIMEHCAGGSLRSLLR-PGKIDEKYIGVIMRELLVALKCIHKDNVIHRDIKAANVLITNEG-NVKLCDFGVAAQV---NQTSLRRQTMAGTPYWMAPEVIMEGVYYDTKVDIWSLGITTYEIATGNPPYCDVEALRAMQLIIKSKPPRLEDRSYSTSLKEFIALCLDEDPKERLSADDLLKSKFIRAHKATPTS 285
[Close]
BLAST of SMED30028687 vs. UniProt/SwissProt
Match: sp|Q13177|PAK2_HUMAN (Serine/threonine-protein kinase PAK 2 OS=Homo sapiens OX=9606 GN=PAK2 PE=1 SV=3)

HSP 1 Score: 129.413 bits (324), Expect = 2.260e-29
Identity = 82/258 (31.78%), Postives = 140/258 (54.26%), Query Frame = -2 
Query:  271 KKLGIGAFAKVKLCKNKLSGRVFALK---MPKNKNINAILNEISIFSTLKSSPSMILFHGIYLHSNKLCIAMEYISGKTLESVLKDENSLDYSLKLQFVFQILQQIKSLHDAGIIHRDISCNNIMIYKENQNAKLIDFGLSISVKGLNTDAIELSGKYGTPWYMAPELLTHEPYSNKIDIWSVGVVAVKIFSGERPYTYLNPTKFQAKIAKDKTIEL-DPQNFSKDVFDFLSPCFKSDPKERPTVDDLLSSKMFQINR 1032
            +K+G GA   V    +   G+  A+K   + K      I+NEI +   LK+ P+++ F   YL  ++L + MEY++G +L  V+  E  +D +       + LQ ++ LH   +IHRDI  +N+++  E  + KL DFG    +     +  + S   GTP++MAPE++T + Y  K+DIWS+G++A+++  GE PY   NP +    IA + T EL +P+  S    DFL+ C + D ++R +  +LL     ++ +
Sbjct:  253 EKIGQGASGTVFTATDVALGQEVAIKQINLQKQPKKELIINEILVMKELKN-PNIVNFLDSYLVGDELFVVMEYLAGGSLTDVVT-ETCMDEAQIAAVCRECLQALEFLHANQVIHRDIKSDNVLLGMEG-SVKLTDFGFCAQI---TPEQSKRSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMVEGEPPYLNENPLRALYLIATNGTPELQNPEKLSPIFRDFLNRCLEMDVEKRGSAKELLQHPFLKLAK 504
[Close]
BLAST of SMED30028687 vs. UniProt/SwissProt
Match: sp|Q29502|PAK2_RABIT (Serine/threonine-protein kinase PAK 2 OS=Oryctolagus cuniculus OX=9986 GN=PAK2 PE=1 SV=1)

HSP 1 Score: 129.413 bits (324), Expect = 2.302e-29
Identity = 82/258 (31.78%), Postives = 140/258 (54.26%), Query Frame = -2 
Query:  271 KKLGIGAFAKVKLCKNKLSGRVFALK---MPKNKNINAILNEISIFSTLKSSPSMILFHGIYLHSNKLCIAMEYISGKTLESVLKDENSLDYSLKLQFVFQILQQIKSLHDAGIIHRDISCNNIMIYKENQNAKLIDFGLSISVKGLNTDAIELSGKYGTPWYMAPELLTHEPYSNKIDIWSVGVVAVKIFSGERPYTYLNPTKFQAKIAKDKTIEL-DPQNFSKDVFDFLSPCFKSDPKERPTVDDLLSSKMFQINR 1032
            +K+G GA   V    +   G+  A+K   + K      I+NEI +   LK+ P+++ F   YL  ++L + MEY++G +L  V+  E  +D +       + LQ ++ LH   +IHRDI  +N+++  E  + KL DFG    +     +  + S   GTP++MAPE++T + Y  K+DIWS+G++A+++  GE PY   NP +    IA + T EL +P+  S    DFL+ C + D ++R +  +LL     ++ +
Sbjct:  253 EKIGQGASGTVFTATDVALGQEVAIKQINLQKQPKKELIINEILVMKELKN-PNIVNFLDSYLVGDELFVVMEYLAGGSLTDVVT-ETCMDEAQIAAVCRECLQALEFLHANQVIHRDIKSDNVLLGMEG-SVKLTDFGFCAQI---TPEQSKRSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMVEGEPPYLNENPLRALYLIATNGTPELQNPEKLSPIFRDFLNRCLEMDVEKRGSAKELLQHPFLKLAK 504
[Close]
BLAST of SMED30028687 vs. UniProt/SwissProt
Match: sp|O61122|SVKA_DICDI (Serine/threonine-protein kinase svkA OS=Dictyostelium discoideum OX=44689 GN=svkA PE=1 SV=1)

HSP 1 Score: 128.642 bits (322), Expect = 2.354e-29
Identity = 85/256 (33.20%), Postives = 134/256 (52.34%), Query Frame = -2 
Query:  280 KKLGIGAFAKVKLCKNKLSGRVFALKM----PKNKNINAILNEISIFSTLKSSPSMILFHGIYLHSNKLCIAMEYISGKTLESVLKDENSLDYSLKLQFVFQILQQIKSLHDAGIIHRDISCNNIMIYKENQNAKLIDFGLSISVKGLNTDAIELSGKY-GTPWYMAPELLTHEPYSNKIDIWSVGVVAVKIFSGERPYTYLNPTKFQAKIAKDKTIELDPQNFSKDVFDFLSPCFKSDPKERPTVDDLLSSKMFQ 1032
            +K+G G+F +V    NK +    A+K          I  I  EI++ S  +S P +  + G +L  +KL I MEY++G ++  ++K     D       + ++L+ ++ LH  G IHRDI   N+++     + KL DFG+S    G  TD +     + GTP++MAPE++    Y +K DIWS+G+ A+++  GE P   L+P +    I KD    L+  NFSK   +F + C   DP +RPT  DLL  K  +
Sbjct:   16 EKIGKGSFGEVFKGINKKTNETIAIKTIDLEDAEDEIEDIQQEINVLSQCES-PFVTKYFGSFLKGSKLWIIMEYLAGGSVLDLMK-PGPFDEGYIAIILRELLKGLEYLHSEGKIHRDIKAANVLLSASG-DVKLADFGVS----GQLTDQMTKRNTFVGTPFWMAPEVIKQTGYDSKADIWSMGITALEMAKGEPPRADLHPMRALFLIPKDPPPTLE-GNFSKGFKEFCALCLNKDPNQRPTAKDLLKHKFIK 263
[Close]
BLAST of SMED30028687 vs. UniProt/SwissProt
Match: sp|Q8CIN4|PAK2_MOUSE (Serine/threonine-protein kinase PAK 2 OS=Mus musculus OX=10090 GN=Pak2 PE=1 SV=1)

HSP 1 Score: 129.413 bits (324), Expect = 2.498e-29
Identity = 82/258 (31.78%), Postives = 140/258 (54.26%), Query Frame = -2 
Query:  271 KKLGIGAFAKVKLCKNKLSGRVFALK---MPKNKNINAILNEISIFSTLKSSPSMILFHGIYLHSNKLCIAMEYISGKTLESVLKDENSLDYSLKLQFVFQILQQIKSLHDAGIIHRDISCNNIMIYKENQNAKLIDFGLSISVKGLNTDAIELSGKYGTPWYMAPELLTHEPYSNKIDIWSVGVVAVKIFSGERPYTYLNPTKFQAKIAKDKTIEL-DPQNFSKDVFDFLSPCFKSDPKERPTVDDLLSSKMFQINR 1032
            +K+G GA   V    +   G+  A+K   + K      I+NEI +   LK+ P+++ F   YL  ++L + MEY++G +L  V+  E  +D +       + LQ ++ LH   +IHRDI  +N+++  E  + KL DFG    +     +  + S   GTP++MAPE++T + Y  K+DIWS+G++A+++  GE PY   NP +    IA + T EL +P+  S    DFL+ C + D ++R +  +LL     ++ +
Sbjct:  253 EKIGQGASGTVFTATDVALGQEVAIKQINLQKQPKKELIINEILVMKELKN-PNIVNFLDSYLVGDELFVVMEYLAGGSLTDVVT-ETCMDEAQIAAVCRECLQALEFLHANQVIHRDIKSDNVLLGMEG-SVKLTDFGFCAQI---TPEQSKRSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMVEGEPPYLNENPLRALYLIATNGTPELQNPEKLSPIFRDFLNRCLEMDVEKRGSAKELLQHPFLKLAK 504
[Close]
BLAST of SMED30028687 vs. TrEMBL
Match: A0A0P4WAY3 (Protein kinase domain-containing protein OS=Scylla olivacea OX=85551 PE=3 SV=1)

HSP 1 Score: 154.836 bits (390), Expect = 4.845e-37
Identity = 85/262 (32.44%), Postives = 149/262 (56.87%), Query Frame = -2 
Query:  274 KLGIGAFAKVKLCKNKLSGRVFALK-MP----KNKNINAILNEISIFSTLKSSPSMILFHGIYLHSNKLCIAMEYISGKTLESVLKD-ENSLDYSLKLQFVFQILQQIKSLHDAGIIHRDISCNNIMIYKENQNAKLIDFGLSISVKGLNTDAIELSGKYGTPWYMAPELL-THEPYSNKIDIWSVGVVAVKIFSGERPYTYLNPT---KFQAKIAKDKTIELDPQNFSKDVFDFLSPCFKSDPKERPTVDDLLSSKMFQIN 1029
            K+G G F KV    N  +G + A+K +P     +++I  + +E  IF  + S P ++  +G+ +H++++ + MEY    TLES+    E  L   L  ++  Q+L+ + +LH+ GI+HRDI   NI + +E    KL DFG ++ ++G +T+  EL+G  GT  YMAPE+  + E +    D+WSVG V +++ +G+RP+   + +    F+  + +  TI   P++ S++  +FL+ CF  DPK+R T   LL     +++
Sbjct:   42 KIGAGRFGKVYTAVNNNTGELMAMKVLPLQPNDHRSIRRVADEFHIFEGI-SHPHLVKCYGVEIHNDEMLMFMEYCDEGTLESLATSTETGLPEELVRKYTRQLLEAVHALHERGIVHRDIKGANIFLTEEGNMLKLGDFGCAVRLRGHHTEVGELAGIVGTHAYMAPEIFQSSEGHGRAADVWSVGCVVIEMATGKRPWPEYDSSVQIMFRVGMGQSPTI---PKHLSEEGHEFLASCFIHDPKKRATTAQLLDHTFVKVD 299
[Close]
BLAST of SMED30028687 vs. TrEMBL
Match: A0A371IGI6 (Mitogen-activated protein kinase kinase kinase NPK1 (Fragment) OS=Mucuna pruriens OX=157652 GN=NPK1 PE=3 SV=1)

HSP 1 Score: 149.443 bits (376), Expect = 3.558e-35
Identity = 95/249 (38.15%), Postives = 133/249 (53.41%), Query Frame = -2 
Query:  298 KKLGIGAFAKVKLCKNKLSGRVFALKMP-KNKNINAILNEISIFSTLKSSPSMILFHGIYLHSNKLCIAMEYISGKTLESVL-KDENSLDYSLKLQFVFQILQQIKSLHDAGIIHRDISCNNIMIYKENQNAKLIDFGLSISVKGLNTDAIELSGKYGTPWYMAPELLTHEPYSNKIDIWSVGVVAVKIFSGERPYT--YLNPTKFQAKIAKDKTIELDPQNFSKDVFDFLSPCFKSDPKERPTVDDLL 1032
            K +G G+F+ V L  NK +G +F +K P +    +A+  EI I  TL SSP ++   GI     KL I MEY++G +L  V  K   SLD  +   +  +IL  I  LH  GI+H D+ CNN+++   + N KL DFG +  VK L      + G   TP +MAPE+L +E      DIWS+G   +++ +G+ P+     NP      IA    I   P +FSKD  DFLS C   +PK R TV +LL
Sbjct:   19 KVVGCGSFSTVHLAMNKSTGGLFVVKSPHEGVGRDALDKEIKILRTLNSSPYIVQCLGIQEDQGKLNIFMEYMAGGSLADVAHKFGGSLDEKVVRIYTREILHGINHLHQHGIVHCDLKCNNVLL-GSSGNIKLADFGCAKRVKDLANSWQSIGG---TPLWMAPEVLRNESLDFAADIWSLGCTVIEMATGKPPWANQLSNPITAVLNIAHGDRIPHFPSHFSKDGLDFLSRCMDREPKNRSTVKELL 263
[Close]
BLAST of SMED30028687 vs. TrEMBL
Match: A0A445DK24 (Protein kinase domain-containing protein OS=Arachis hypogaea OX=3818 GN=Ahy_A04g021377 PE=3 SV=1)

HSP 1 Score: 145.206 bits (365), Expect = 1.821e-33
Identity = 88/249 (35.34%), Postives = 131/249 (52.61%), Query Frame = -2 
Query:  298 KKLGIGAFAKVKLCKNKLSGRVFALKMPK-NKNINAILNEISIFSTLKSSPSMILFHGIYLHSNKLCIAMEYISGKTLESVLKD-ENSLDYSLKLQFVFQILQQIKSLHDAGIIHRDISCNNIMIYKENQNAKLIDFGLSISVKGLNTDAIELSGKYGTPWYMAPELLTHEPYSNKIDIWSVGVVAVKIFSGERPYT--YLNPTKFQAKIAKDKTIELDPQNFSKDVFDFLSPCFKSDPKERPTVDDLL 1032
            K +G G+F  V L  NK +G +F +K         A+ NE+ I  +L SSP ++ + G       L + MEY++G +L  V +    SLD  +   +  +IL  ++ LH  GI+H D+ C N+++   + N KL DFG +  VK L   A  L G   TP +MAPE+L +E      DIWS+G   +++ +G  P+     NP     +IA    I   P +FSK+  DFL+ C + DPK+R T  DLL
Sbjct:   20 KLVGTGSFGTVNLAMNKSTGGLFVVKSAHIGAGCEALSNEVKILESLSSSPYIVQYLGKEEDQGNLNVFMEYMAGGSLADVAQKFGGSLDEDVVRLYTREILHGLQHLHQHGIVHCDLKCKNVLL-GSSGNIKLADFGCAKRVKDLKA-AARLGG---TPLWMAPEVLRNEQLDVSADIWSLGCTVIEMATGRYPWAGEVSNPMASVLRIANGDEIPQLPAHFSKEGLDFLTRCLERDPKKRCTAQDLL 263
[Close]
BLAST of SMED30028687 vs. TrEMBL
Match: A0A444ZC67 (Protein kinase domain-containing protein OS=Arachis hypogaea OX=3818 GN=Ahy_B04g069280 PE=3 SV=1)

HSP 1 Score: 144.821 bits (364), Expect = 2.040e-33
Identity = 88/249 (35.34%), Postives = 131/249 (52.61%), Query Frame = -2 
Query:  298 KKLGIGAFAKVKLCKNKLSGRVFALKMPK-NKNINAILNEISIFSTLKSSPSMILFHGIYLHSNKLCIAMEYISGKTLESVLKD-ENSLDYSLKLQFVFQILQQIKSLHDAGIIHRDISCNNIMIYKENQNAKLIDFGLSISVKGLNTDAIELSGKYGTPWYMAPELLTHEPYSNKIDIWSVGVVAVKIFSGERPYT--YLNPTKFQAKIAKDKTIELDPQNFSKDVFDFLSPCFKSDPKERPTVDDLL 1032
            K +G G+F  V L  NK +G +F +K         A+ NE+ I  +L SSP ++ + G       L + MEY++G +L  V +    SLD  +   +  +IL  ++ LH  GI+H D+ C N+++   + N KL DFG +  VK L   A  L G   TP +MAPE+L +E      DIWS+G   +++ +G  P+     NP     +IA    I   P +FSK+  DFL+ C + DPK+R T  DLL
Sbjct:   20 KLVGTGSFGTVNLAMNKSTGGLFVVKSAHIGGGCEALSNEVKILESLSSSPYIVQYLGKEEDQGNLNVFMEYMAGGSLADVAQKFGGSLDEDVVRLYTREILHGLQHLHQHGIVHCDLKCKNVLL-GSSGNIKLADFGCAKRVKDLKA-AARLGG---TPLWMAPEVLRNEQLDVSADIWSLGCTVIEMATGRYPWAGEVSNPMASVLRIANGDEIPQLPAHFSKEGLDFLTKCLERDPKKRCTAQDLL 263
[Close]
BLAST of SMED30028687 vs. TrEMBL
Match: A0A0C3LVR5 (Protein kinase domain-containing protein OS=Tulasnella calospora MUT 4182 OX=1051891 GN=M407DRAFT_75683 PE=4 SV=1)

HSP 1 Score: 142.895 bits (359), Expect = 2.751e-33
Identity = 90/276 (32.61%), Postives = 151/276 (54.71%), Query Frame = -2 
Query:  223 KKLGIGAFAKVKLCKNKLSGRVFALKM----PKNKNINAILNEISIFSTLKSSPSMILFHGIYLHSNKLCIAMEYISGKTLESVLKDENSLDYSLKLQFVFQILQQIKSLHDAGIIHRDISCNNIMIYKENQNAKLIDFGLSISVKGLNTDAIELSGKYGTPWYMAPELLTHEPYSNKIDIWSVGVVAVKIFSGERPYTYLNPTKFQAKIAKDKTIELDPQNFSKDVFDFLSPCFKSDPKERPTVDDLLSSK-MFQINRSWQISR-ISRTD*WRKA 1032
            +++G G+F +V     K S +V A+K+         I  I  EI I S L  SP +  +HG +L  + L I MEY +G +   ++K     +  + +  + ++L+ ++ LH  G +HRDI   NI++  +  + KL DFG+S  + G  T + + +   GTP++M+PE++    Y +K DIWS+G+ A+++  GE PY  L+P K    I K+    L+   FSK   DF++ C + DP+ERPT  DLL  K + +  R+  ++  + R + W+ A
Sbjct:   15 ERIGKGSFGEVYKGFEKASKKVVAIKIIDLESAEDEIEDIQQEIQILSQL-DSPFVTKYHGSFLKGSNLWIVMEYCAGGSCSDLMKAGVFREEYIAI-IIKELLKGLEYLHQEGKLHRDIKAANILLSGDG-SVKLADFGVSGQLSG--TLSAKKNTFVGTPYWMSPEVIKQSGYDHKADIWSLGITAIELAKGEPPYAELHPMKVLFLIPKNPPPTLEGPEFSKLFKDFVACCLRRDPRERPTARDLLRHKWILKAKRTNYLTELLERQERWKMA 285
[Close]
BLAST of SMED30028687 vs. Ensembl Cavefish
Match: pak2b (p21 protein (Cdc42/Rac)-activated kinase 2b [Source:ZFIN;Acc:ZDB-GENE-030131-3759])

HSP 1 Score: 127.102 bits (318), Expect = 1.058e-29
Identity = 80/258 (31.01%), Postives = 139/258 (53.88%), Query Frame = -2 
Query:  271 KKLGIGAFAKVKLCKNKLSGRVFALK---MPKNKNINAILNEISIFSTLKSSPSMILFHGIYLHSNKLCIAMEYISGKTLESVLKDENSLDYSLKLQFVFQILQQIKSLHDAGIIHRDISCNNIMIYKENQNAKLIDFGLSISVKGLNTDAIELSGKYGTPWYMAPELLTHEPYSNKIDIWSVGVVAVKIFSGERPYTYLNPTKFQAKIAKDKTIELD-PQNFSKDVFDFLSPCFKSDPKERPTVDDLLSSKMFQINR 1032
            +K+G GA   V    +  +G+  A+K   + K      I+NEI +   LK+ P+++ F   +L   +L + MEY++G +L  V+  E  +D +       + LQ ++ LH   +IHRDI  +N+++  +  + KL DFG    +     +  + S   GTP++MAPE++T + Y  K+DIWS+G++A+++  GE PY   NP +    IA + T EL  P+  S    DFL+ C + D ++R +  +LL     ++ +
Sbjct:  218 EKIGQGASGTVYTAIDVATGQEVAIKQINLQKQPKKELIINEILVMKELKN-PNIVNFLDSFLVGEELFVVMEYLAGGSLTDVVT-ETCMDEAQIAAVCRECLQALEFLHANQVIHRDIKSDNVLLGMDG-SVKLTDFGFCAQI---TPEQSKRSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMVEGEPPYLNENPLRALYLIATNGTPELQSPEKLSPIFRDFLARCLEMDVEKRGSSKELLQHPFLKLAK 469
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BLAST of SMED30028687 vs. Ensembl Cavefish
Match: stk24b (serine/threonine-protein kinase 24-like [Source:NCBI gene;Acc:103028447])

HSP 1 Score: 125.561 bits (314), Expect = 1.280e-29
Identity = 85/256 (33.20%), Postives = 138/256 (53.91%), Query Frame = -2 
Query:  283 LKKLGIGAFAKVKLCKNKLSGRVFALKM----PKNKNINAILNEISIFSTLKSSPSMILFHGIYLHSNKLCIAMEYISGKTLESVLKDENSLDYSLKLQFVFQILQQIKSLHDAGIIHRDISCNNIMIYKENQNAKLIDFGLSISVKGLNTDA-IELSGKYGTPWYMAPELLTHEPYSNKIDIWSVGVVAVKIFSGERPYTYLNPTKFQAKIAKDKTIELDPQNFSKDVFDFLSPCFKSDPKERPTVDDLLSSKMF 1035
            L+++G G+F +V    +  + +V A+K+         I  I  EI++ S    SP +  ++G YL   KL I MEY+ G +   +L +  +LD +     + +IL+ ++ LH    IHRDI   N+++  E    KL DFG    V G  TD  I+ +   GTP++MAPE++    Y +K DIWS+G+ A+++  GE P++ L+P K    I K+    L+  N+SK + +F+  C   +P  RPT  +LL  K+ 
Sbjct:   27 LERIGKGSFGEVFKGIDNRTQKVVAIKIIDLEEAEDEIEDIQQEITVLSQC-DSPFVTKYYGSYLKGTKLWIIMEYLGGGSALDLL-EPGALDETQIATILREILKGLEYLHSEKKIHRDIKAANVLL-SEQGEVKLADFG----VAGQLTDTQIKRNTFVGTPFWMAPEVIKQSAYDSKADIWSLGITAIELAKGEPPHSDLHPMKVLFLIPKNNPPTLE-GNYSKPLKEFVEACLNKEPSFRPTAKELLKHKLI 274
[Close]
BLAST of SMED30028687 vs. Ensembl Cavefish
Match: ENSAMXT00000008518.2 (pep primary_assembly:Astyanax_mexicanus-2.0:19:14507502:14520436:1 gene:ENSAMXG00000008289.2 transcript:ENSAMXT00000008518.2 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 124.405 bits (311), Expect = 1.799e-29
Identity = 89/277 (32.13%), Postives = 144/277 (51.99%), Query Frame = -2 
Query:  229 LKKLGIGAFAKVKLCKNKLSGRVFALKM----PKNKNINAILNEISIFSTLKSSPSMILFHGIYLHSNKLCIAMEYISGKTLESVLKDENSLDYSLKLQFVFQILQQIKSLHDAGIIHRDISCNNIMIYKENQNAKLIDFGLSISVKGLNTDA-IELSGKYGTPWYMAPELLTHEPYSNKIDIWSVGVVAVKIFSGERPYTYLNPTKFQAKIAKDKTIELDPQNFSKDVFDFLSPCFKSDPKERPTVDDLLSSKM---FQINRSWQISRISRTD*WR 1035
            L+K+G G+F +V    +  + +V A+K+         I  I  EI++ S    SP +  ++G YL   KL I MEY+ G +   +L +   LD +     + +IL+ ++ LH    IHRDI   N+++  E  + KL DFG    V G  TD  I+ +   GTP++MAPE++    Y +K DIWS+G+ A+++  GE P++ L+P K    I K+    L+  N+ K + +F+  C   +P  RPT  +LL  K+   +    S+    I R   W+
Sbjct:   24 LEKIGKGSFGEVFKGIDNRTQKVVAIKIIDLEEAEDEIEDIQQEITVLSQC-DSPFVTKYYGSYLKGTKLWIIMEYLGGGSALDLL-EPGPLDETQIATILREILKGLEYLHSEKKIHRDIKAANVLL-SEQGDVKLADFG----VAGQLTDTQIKRNTFVGTPFWMAPEVIKQSAYDSKADIWSLGITAIELAKGEPPHSELHPMKVLFLIPKNNPPTLE-GNYCKPLKEFVEACLNKEPSFRPTAKELLKHKLIVRYAKKTSYLTELIDRYKRWK 292
[Close]
BLAST of SMED30028687 vs. Ensembl Cavefish
Match: stk17b (serine/threonine kinase 17b [Source:NCBI gene;Acc:103028616])

HSP 1 Score: 123.25 bits (308), Expect = 1.941e-29
Identity = 78/263 (29.66%), Postives = 133/263 (50.57%), Query Frame = -2 
Query:  295 VLKKLGIGAFAKVKLCKNKLSGRVFALKMPKNKNIN-----AILNEISIFSTLKSSPSMILFHGIYLHSNKLCIAMEYISG-KTLESVLKDENSLDYSLKLQFVFQILQQIKSLHDAGIIHRDISCNNIMIYKEN--QNAKLIDFGLSISVKGLNTDAIELSGKYGTPWYMAPELLTHEPYSNKIDIWSVGVVAVKIFSGERPY-------TYLNPTKFQAKIAKDKTIELDPQNFSKDVFDFLSPCFKSDPKERPTVDDLLS 1038
            V  +LG G FA VK C  K +G+VFA K  + +         +++E+++    KS+P ++  H  Y   + + + +EY +G +  E  + DE  L     ++ + Q L+ I  LH + ++H D+   NI++   N   + KL+DFGL+  +      A EL    GTP Y+APE+L +EP +   D+WSVGV+   + +GE P+       T+LN ++     +K+    +     S+    F+       P++RP+  D LS
Sbjct:   34 VTGELGRGKFAVVKKCVEKATGKVFAAKFVRKRRRGRDCKAEVIHEMAVLEAAKSNPRVVNLHAAYETEHDIVLLLEYAAGGEIFEHCVSDE-LLSEGQVIRLIRQTLEGIHQLHQSNVVHLDLKPQNILLTSLNPLGDIKLVDFGLARRL----GSAGELREILGTPEYVAPEILNYEPITTASDLWSVGVITYMLITGESPFAGEDKQQTFLNVSQVNVDYSKEAFARV-----SELAVHFIRKLLVKAPEDRPSAADCLS 286
[Close]
BLAST of SMED30028687 vs. Ensembl Cavefish
Match: STK4 (serine/threonine kinase 4 [Source:HGNC Symbol;Acc:HGNC:11408])

HSP 1 Score: 125.561 bits (314), Expect = 1.961e-29
Identity = 82/258 (31.78%), Postives = 135/258 (52.33%), Query Frame = -2 
Query:  283 EVLKKLGIGAFAKVKLCKNKLSGRVFALK-MPKNKNINAILNEISIFSTLKSSPSMILFHGIYLHSNKLCIAMEYISGKTLESVLKDENSLDYSLKLQFVFQ-ILQQIKSLHDAGIIHRDISCNNIMIYKENQNAKLIDFGLSISVKGLNTDAIELSGKY-GTPWYMAPELLTHEPYSNKIDIWSVGVVAVKIFSGERPYTYLNPTK--FQAKIAKDKTIELDPQNFSKDVFDFLSPCFKSDPKERPTVDDLLSSKMF 1041
            +VL+KLG G++  V     K +G + A+K +P   ++  I+ EISI     +SP ++ ++G Y  ++ L I MEY    ++  +++  N      ++  + Q  L+ ++ LH    IHRDI   NI++  E Q AKL DFG    V G  TD +       GTP++MAPE++    Y+   DIWS+G+ A+++  G+ PY  ++P +  F        T   +P  +S+   DF+S C   +P+ R T   LL   +F
Sbjct:   34 DVLEKLGEGSYGSVFKAHYKETGEIVAIKQVPVESDLQEIIKEISIMQQC-NSPHVVRYYGSYFKNSDLWIVMEYCGAGSVSDIIRQRNKTLAEDEIAAILQSTLKGLEYLHFMRKIHRDIKAGNILLNSEGQ-AKLADFG----VAGQLTDTMAKRNTVIGTPFWMAPEVIQEIGYNCVADIWSLGITAIEMAEGKPPYADIHPMRAIFMIPTNPPPTFR-NPDQWSEPFRDFVSQCLVKNPENRATATQLLQVFIF 284
[Close]
BLAST of SMED30028687 vs. Ensembl Sea Lamprey
Match: map3k2 (mitogen-activated protein kinase kinase kinase 2 [Source:ZFIN;Acc:ZDB-GENE-120215-96])

HSP 1 Score: 120.168 bits (300), Expect = 1.297e-27
Identity = 80/268 (29.85%), Postives = 131/268 (48.88%), Query Frame = -2 
Query:  274 NIEVLKKLGIGAFAKVKLCKNKLSGRVFALK--------MPKNKNINAILNEISIFSTLKSSPSMILFHGIYLHSNK--LCIAMEYISGKTLESVLKDENSLDYSLKLQFVFQILQQIKSLHDAGIIHRDISCNNIMIYKENQNAKLIDFGLSISVKGLNTDAIELSGKYGTPWYMAPELLTHEPYSNKIDIWSVGVVAVKIFSGERPYTYLNPTKFQAKIAKDKTIELDPQNFSKDVFDFLSPCFKSDPKERPTVDDLLSSKMFQIN 1047
            N +  K LG GAF +V LC +  +GR  A+K        +  +K +NA+  EI +   L+    ++ + G      +  L I MEY+ G +++  L+   +L  ++  ++  QIL+ +  LH   I+HRDI   NI+      N KL DFG S  ++ + +    +    GTP++M+PE++  E Y  K DIWSVG   V++ + + P+          KIA   T    P + S+   D L   F  + K RP+ +DLL      ++
Sbjct:  358 NWQRGKLLGQGAFGRVYLCYDADTGRELAVKQVQFDPGSVETSKEVNALECEIQLLKNLQHE-RIVQYFGCLRDPQQKTLSIFMEYMPGGSIKDQLRAYGALTENVTRKYTRQILEGVSFLHGNMIVHRDIKGANIL-RDSTGNVKLGDFGASKRLQTICSQGTAMRSVTGTPYWMSPEVINGEGYGRKADIWSVGCTVVEMLTEKPPWAEFEAMAAIFKIATQPTDPRLPLHASEHARDLLRRIF-VEAKLRPSAEDLLRHPFVHVH 622
[Close]
BLAST of SMED30028687 vs. Ensembl Sea Lamprey
Match: stk25a (serine/threonine kinase 25a [Source:ZFIN;Acc:ZDB-GENE-041010-92])

HSP 1 Score: 111.309 bits (277), Expect = 1.450e-25
Identity = 84/258 (32.56%), Postives = 131/258 (50.78%), Query Frame = -2 
Query:  280 KKLGIGAFAKVKLCKNKLSGRVFALKM----PKNKNINAILNEISIFSTLKSSPSMILFHGIYLHSNKLCIAMEYISGKTLESVLKDENSLDYSLKLQFVFQILQQIKSLHDAGIIHRDI--SCNNIMIYKENQNAKLIDFGLSISVKGLNTDA-IELSGKYGTPWYMAPELLTHEPYSNKIDIWSVGVVAVKIFSGERPYTYLNPTKFQAKIAKDKTIELDPQNFSKDVFDFLSPCFKSDPKERPTVDDLLSSKMFQ 1032
            +++G G+F +V    +  +  V A+K+         I  I  EI++ S    SP +  + G YL   KL I MEY+ G +   ++K    L+       + +IL+ +  LH    IHRDI     N+++  E  + KL DFG    V G  TD  I+ +   GTP++MAPE++    Y  K DIWS+G+ A+++  GE P + L+P +    I K+    L+  N+SK   +F+  C   DP+ RPT  +LL  K  Q
Sbjct:   30 ERIGKGSFGEVFKGIDNRTKEVVAIKIIDLEEAEDEIEDIQQEITVLSQC-DSPYVTHYFGSYLKGTKLWIIMEYLGGGSALDLIKP-GPLEEHQIATILREILKGLDYLHSERKIHRDIKGPAANVLL-SEQGDVKLADFG----VAGQLTDTQIKRNTFVGTPFWMAPEVIKQSAYDFKADIWSLGITAIELAKGEPPNSELHPMRVLFLIPKNNPPTLE-GNYSKAFKEFVDSCLNKDPQFRPTAKELLKHKFIQ 279
[Close]
BLAST of SMED30028687 vs. Ensembl Sea Lamprey
Match: slka (STE20-like kinase a [Source:ZFIN;Acc:ZDB-GENE-050411-66])

HSP 1 Score: 115.161 bits (287), Expect = 1.562e-25
Identity = 82/251 (32.67%), Postives = 131/251 (52.19%), Query Frame = -2 
Query:  319 VLKKLGIGAFAKVKLCKNKLSGRVFALKMPKNKNINAILN---EISIFSTLKSSPSMILFHGIYLHSNKLCIAMEYISGKTLESVLKD-ENSLDYSLKLQFVFQILQQIKSLHDAGIIHRDISCNNIMIYKENQNAKLIDFGLSISVKGLNTDAIELSGKY-GTPWYMAPELLTHE-----PYSNKIDIWSVGVVAVKIFSGERPYTYLNPTKFQAKIAKDKTIELD-PQNFSKDVFDFLSPCFKSDPKER 1038
            V+ +LG GAF KV   +NK SG + A K+ + K+   + +   EI I + L   P+++     + + NKL I +E+  G  +++++ + E  L          Q+L+ +  LH   IIHRD+   NI++  E  + KL DFG+S      NT  ++    + GTP++MAPE++  E     PY  K DIWS+G+  +++   E P   LNP +   KIAK+    L  P  +S +  DFL  C   +P+ R
Sbjct:   35 VIGELGDGAFGKVYKAQNKESGVLAAAKVIETKSEEELEDYMVEIEILA-LCDHPNIVGLLNAFYYENKLWIFIEFCPGGAVDAIMLELERGLAEPQIRVVCKQMLEALNYLHTHRIIHRDLKAGNILLTFEG-DVKLADFGVSAK----NTRTLQRRDSFIGTPYWMAPEVVMCETMKDAPYDYKADIWSLGITLIELAQMEPPNHELNPMRVMLKIAKNDPPSLSFPSKWSAEFTDFLKKCLDKNPETR 279
[Close]
BLAST of SMED30028687 vs. Ensembl Sea Lamprey
Match: map3k19 (mitogen-activated protein kinase kinase kinase 19 [Source:ZFIN;Acc:ZDB-GENE-081104-140])

HSP 1 Score: 107.071 bits (266), Expect = 2.939e-25
Identity = 71/264 (26.89%), Postives = 126/264 (47.73%), Query Frame = -2 
Query:  295 KLGIGAFAKVKLCKNKLSGRVFALK---------------MPKNKNINAILNEISIFSTLKSSPSMILFHGIYLHSNKLCIAMEYISGKTLESVLKDENSLDYSLKLQFVFQILQQIKSLHDAGIIHRDISCNNIMIYKENQNAKLIDFGLSISVKGLNTDAIELSG---KYGTPWYMAPELLTHEPYSNKIDIWSVGVVAVKIFSGERPYTYLNPTKFQAKIA-KDKTIELDPQNFSKDVFDFLSPCFKSDPKERPTVDDLLS 1029
            +LG GAF  V L      G++ A+K                 K   +  + +E+ + +TL   P+++ + G  +  N+  I ME++ G T+   ++    L  S+   ++ Q+ + +  LH  G++H D+  +N +I       KLIDFG +  V  L     E  G    +GT ++MAPE++    Y+ + D+WS+G    ++  G  P+  + P      I  ++  +   PQ FSK+  +F+  CF  D  +RP+  +LLS
Sbjct:   20 RLGKGAFGTVFLGLTN-QGKLIAVKELELRDAQSANGNQGGQKQSELQKLQDEVELLTTLHH-PNVVEYLGTEMEGNRFSIFMEFVPGGTVAETVRGFGPLGESVCRSYIAQMTRGLAYLHGHGVMHGDVKGSNAVITPAGV-VKLIDFGCAQRVA-LALSCHENGGLHSVHGTAYWMAPEVINGTGYARRADVWSLGCTLHEMAVGRPPFADMAPMAALLHIGIRNGIMPGLPQAFSKEAQEFVEQCFIRDKLKRPSSQELLS 279
[Close]
BLAST of SMED30028687 vs. Ensembl Sea Lamprey
Match: NEK9 (NIMA related kinase 9 [Source:HGNC Symbol;Acc:HGNC:18591])

HSP 1 Score: 112.079 bits (279), Expect = 8.993e-25
Identity = 81/279 (29.03%), Postives = 145/279 (51.97%), Query Frame = -2 
Query:  244 LKKLGIGAFAKVKLCKNKLSGRVFALK-----MPKNKNINAILNEISIFSTLKSSPSMILFHGIYLHSNKLCIAMEYISGKTL-ESVLKDENSLDYSLK--LQFVFQILQQIKSLHDAGIIHRDISCNNIMIYKENQNAKLIDFGLSISVKGLNTDAIELSGKYGTPWYMAPELLTHEPYSNKIDIWSVGVVAVKIFSGERPYTYLNPTKFQAKIAKD-KTIELDPQNFSKDVFDFLSPCFKSDPKERPTVDDLLSSKMFQINRS------WQISRISR 1035
            ++ LG GAF +  L +      +   K        +K      NEI I S L+ + ++I ++  +L  N L I +EY +G TL E ++K   +  +  K  + + +Q++  ++ +H+  I+HRDI   NI + K +   K+ DFG+S   K L++ +       GTP+YM+PEL+  + Y+ K DIW++G V  ++ +  R +   NP K   +I    K +E+D Q +SK++ + +  C + D ++RPT +DLL     +  R       W+++  +R
Sbjct:   39 VRVLGRGAFGEAALYRRNEDNSLVVWKEIDLTRLSDKERRDSQNEIDILSLLEHA-NIISYYNHFLDGNVLLIELEYCNGGTLYEKIIKQHGAF-FPEKDIVWYFYQLVSAVEQIHNFKILHRDIKTLNIFLTKSDL-IKVGDFGIS---KILDSRSQMAESYVGTPYYMSPELIRGDKYNTKSDIWAMGCVLYELLTLTRTFDATNPLKLCYEIIHGKKQVEIDDQ-YSKEIKEVVQKCLQQDAEQRPTAEDLLELSPIKTRRREMEKNVWRLNEPAR 310
[Close]
BLAST of SMED30028687 vs. Ensembl Yeast
Match: KIC1 (Protein kinase of the PAK/Ste20 family, required for cell integrity; physically interacts with Cdc31p (centrin), which is a component of the spindle pole body; part of the RAM network that regulates cellular polarity and morphogenesis [Source:SGD;Acc:S000001144])

HSP 1 Score: 133.265 bits (334), Expect = 2.498e-31
Identity = 82/262 (31.30%), Postives = 138/262 (52.67%), Query Frame = -2 
Query:  256 LGIGAFAKVKLCKNKLSGRVFALKM----PKNKNINAILNEISIFSTLKSSPSMILFHGIYLHSNKLCIAMEYISGKTLESVLKDENSLDYSLKLQFVFQILQQIKSLHDAGIIHRDISCNNIMIYKENQNAKLIDFGLSISVKGLNTDAIELSGKYGTPWYMAPELLTHEPY-SNKIDIWSVGVVAVKIFSGERPYTYLNPTKFQAKIAKDKTIELDPQNFSKDVFDFLSPCFKSDPKERPTVDDLLSSKMFQINRSWQIS 1026
            +G G F  V    N  +GRV+A+K+      +  +  +  EI   ++LK   ++  ++G YL    L I ME+ +G +L S+L+    +D       + ++L  +K +H   +IHRDI   N++I  E  N KL DFG++  V   N  ++      GTP++MAPE++    Y   K+DIWS+G+   +I +G  PY  +   +    I K K   L+ +++S  + +F++ C   DPKER + DDLL SK  + +++   S
Sbjct:   29 IGRGKFGVVYKGYNVKTGRVYAIKVLNLDSDSDEVEDVQREIQFLASLKQISNITRYYGSYLKDTSLWIIMEHCAGGSLRSLLR-PGKIDEKYIGVIMRELLVALKCIHKDNVIHRDIKAANVLITNEG-NVKLCDFGVAAQV---NQTSLRRQTMAGTPYWMAPEVIMEGVYYDTKVDIWSLGITTYEIATGNPPYCDVEALRAMQLIIKSKPPRLEDRSYSTSLKEFIALCLDEDPKERLSADDLLKSKFIRAHKATPTS 285
[Close]
BLAST of SMED30028687 vs. Ensembl Yeast
Match: BCK1 (MAPKKK acting in the protein kinase C signaling pathway; the kinase C signaling pathway controls cell integrity; upon activation by Pkc1p phosphorylates downstream kinases Mkk1p and Mkk2p; MAPKKK is an acronym for mitogen-activated protein (MAP) kinase kinase kinase [Source:SGD;Acc:S000003631])

HSP 1 Score: 123.635 bits (309), Expect = 2.665e-28
Identity = 83/269 (30.86%), Postives = 157/269 (58.36%), Query Frame = -2 
Query:  265 LGIGAFAKVKLCKNKLSGRVFALK---MPKNKNIN-AILNEI----SIFSTLKS--SPSMILFHGIYLHSNKLCIAMEYISGKTLESVLKDENSLDYSLKLQFVFQILQQIKSLHDAGIIHRDISCNNIMIYKENQNAKLIDFGLSISVKGLNTDAIELSGKYGTPWYMAPELL-THEPYSNKIDIWSVGVVAVKIFSGERPYTYLNPTKFQAKIAKDKTIELDPQN----FSKDVFDFLSPCFKSDPKERPTVDDLLSSKMFQINRSW 1026
            +G G+F  V LC N  +G + A+K   +PK  + N AIL+ +    S  STLK     +++ + G    +N   + +EY++G ++ S+++     D  L      Q+L+ +  LH  GI+HRD+  +N+++ ++    K+ DFG+S   K + +++ +++ + GT ++MAPE++ T + YS K+DIWS+G + +++F+G+RP++ L       KI K K+    P++     S+   +FL  CF+ +P++RPT ++LLS    ++N ++
Sbjct: 1181 IGKGSFGAVYLCLNVTTGEMMAVKQVEVPKYSSQNEAILSTVEALRSEVSTLKDLDHLNIVQYLGFENKNNIYSLFLEYVAGGSVGSLIRMYGRFDEPLIKHLTTQVLKGLAYLHSKGILHRDMKADNLLLDQDGI-CKISDFGISRKSKDIYSNS-DMTMR-GTVFWMAPEMVDTKQGYSAKVDIWSLGCIVLEMFAGKRPWSNLEVVAAMFKIGKSKSAPPIPEDTLPLISQIGRNFLDACFEINPEKRPTANELLSHPFSEVNETF 1446
[Close]
BLAST of SMED30028687 vs. Ensembl Yeast
Match: TPK2 (cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; partially redundant with Tpk1p and Tpk3p; localizes to P-bodies during stationary phase; relocalizes to the cytosol in response to hypoxia [Source:SGD;Acc:S000006124])

HSP 1 Score: 113.62 bits (283), Expect = 7.379e-27
Identity = 68/250 (27.20%), Postives = 125/250 (50.00%), Query Frame = -2 
Query:  319 MDNIEVLKKLGIGAFAKVKLCKNKLSGRVFALKMPKNKNINAI-----LNEISIFSTLKSSPSMILFHGIYLHSNKLCIAMEYISGKTLESVLKDENSLDYSLKLQFVFQILQQIKSLHDAGIIHRDISCNNIMIYKENQNAKLIDFGLSISVKGLNTDAIELSGKYGTPWYMAPELLTHEPYSNKIDIWSVGVVAVKIFSGERPYTYLNPTKFQAKIAKDKTIELDPQNFSKDVFDFLSPCFKSDPKER 1053
            + + ++++ LG G+F +V L ++  +GR +A+K+ K + +  +      N+      L   P +I   G +  +  + + M+YI G  L S+L+        +   +  +++  ++ LH   II+RD+   NI++   N + K+ DFG +  V+ +           GTP Y+APE++T +PY+  +D WS+GV+  ++ +G  P+    P K   KI + K +   P  F  DV D LS    +D   R
Sbjct:   67 LHDFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKQQVVKMKQVEHTNDERRMLKLVEHPFLIRMWGTFQDARNIFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVILALEYLHAHNIIYRDLKPENILL-DRNGHIKITDFGFAKEVQTVTWTLC------GTPDYIAPEVITTKPYNKSVDWWSLGVLIYEMLAGYTPFYDTTPMKTYEKILQGKVVY--PPYFHPDVVDLLSKLITADLTRR 307
[Close]
BLAST of SMED30028687 vs. Ensembl Yeast
Match: CDC15 (Protein kinase of the Mitotic Exit Network; localized to the spindle pole bodies at late anaphase; promotes mitotic exit by directly switching on the kinase activity of Dbf2p; required for spindle disassembly after meiosis II; relocalizes to the cytoplasm upon DNA replication stress [Source:SGD;Acc:S000000072])

HSP 1 Score: 115.161 bits (287), Expect = 7.118e-26
Identity = 80/247 (32.39%), Postives = 127/247 (51.42%), Query Frame = -2 
Query:  298 LGIGAFAKVKLCKNKLSGRVFALK---MPKNKNINAILNEISIFSTLKSSPSMILFHGIYLHSNKLCIAMEYISGKTLESVL-KDENSLDYSLKLQFVFQILQQIKSLHDAGIIHRDISCNNIMIYKENQNAKLIDFGLSISVKGLNTDAIELSGKYGTPWYMAPELLTHEPYSNKIDIWSVGVVAVKIFSGERPYTYLNPTKFQAKIAKDKTIELDPQNFSKDVFDFLSPCFKSDPKERPTVDDLL 1026
            +G G++  V    NK + +V A+K      ++ +N I+ EIS+   L  + +++ +HG    S +L I +EY +  +L  ++ +    L  +    +V Q L  +K LH  G+IHRDI   NI++  +N   KL DFG+S  V   N+ A+ L+G      +MAPE+L +   S   DIWS+G   V++ +   PY  L        +  D      P +FS+ + DFLS CF  +  +RPT D LL
Sbjct:   31 IGRGSYGVVYKAINKHTDQVVAIKEVVYENDEELNDIMAEISLLKNLNHN-NIVKYHGFIRKSYELYILLEYCANGSLRRLISRSSTGLSENESKTYVTQTLLGLKYLHGEGVIHRDIKAANILLSADN-TVKLADFGVSTIV---NSSALTLAGTLN---WMAPEILGNRGASTLSDIWSLGATVVEMLTKNPPYHNLTDANIYYAVENDTYYP--PSSFSEPLKDFLSKCFVKNMYKRPTADQLL 267
[Close]
BLAST of SMED30028687 vs. Ensembl Yeast
Match: MKK2 (MAPKK involved in the protein kinase C signaling pathway; involved in control of cell integrity; upon activation by Bck1p phosphorylates downstream target, Slt2p; functionally redundant with Mkk1p; MKK2 has a paralog, MKK1, that arose from the whole genome duplication [Source:SGD;Acc:S000006061])

HSP 1 Score: 111.309 bits (277), Expect = 2.118e-25
Identity = 84/272 (30.88%), Postives = 134/272 (49.26%), Query Frame = -2 
Query:  298 DNIEVLKKLGIGAFAKVKLCKNKLSGRVFALKMPKNKNIN-----AILNEISIFSTLKSSPSMILFHGIYL--HSNKLCIAMEYISGKTLES----VLKDENSLDYSLKLQFVFQILQQIKSLHDAGIIHRDISCNNIMIYKENQNAKLIDFGLSISVKGLNTDAIELSGKYGTPWYMAPELLTHEPYSNKIDIWSVGVVAVKIFSGERPYTYLNPTKFQAKIAKDKTI-ELDPQ---------NFSKDVFDFLSPCFKSDPKERPTVDDLL 1050
            D I  L  LG GA   V  C+ K   +VFALK     N +      I  E+    + KS   ++ ++G++    S+ + IAMEY+ GK+LE+    +LK    +   +  +    +L+ +  LH+  +IHRDI   NI++  E    KL DFG  +S + +N+ A+  +G   T +YMAPE +  +PYS   D+WS+G+  +++  G  P+     T+  A I     I    PQ         ++SK    F+  C K D +ERP+   +L
Sbjct:  212 DEITTLGILGEGAGGSVAKCRLKNGKKVFALKTINTMNTDPEYQKQIFRELQFNKSFKSD-YIVQYYGMFTDEQSSSIYIAMEYMGGKSLEATYKNLLKRGGRISERVIGKIAESVLRGLSYLHERKVIHRDIKPQNILL-NEKGEIKLCDFG--VSGEAVNSLAMTFTG---TSFYMAPERIQGQPYSVTCDVWSLGLTLLEVAGGRFPFESDKITQNVAPIELLTMILTFSPQLKDEPELDISWSKTFRSFIDYCLKKDARERPSPRQML 476
[Close]
BLAST of SMED30028687 vs. Ensembl Nematostella
Match: EDO41410 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S4G7])

HSP 1 Score: 133.65 bits (335), Expect = 2.829e-34
Identity = 82/262 (31.30%), Postives = 132/262 (50.38%), Query Frame = -2 
Query:  298 MDNIEVLKKLGIGAFAKVKLCKNKLSGRVFALKMPKNKNIN--------AILNEISIFSTLKSSPSMILFHGIYLHSNKLCIAMEYISGKTLESVLKDENSLDYSLKLQFVFQILQQIKSLHDAGIIHRDISCNNIM--IYKENQNAKLIDFGLSISVKGLNTDAIELSGKYGTPWYMAPELLTHEPYSNKIDIWSVGVVAVKIFSGERPYTYLNPTKFQAKIAKDKTIELDPQNFSKDVFDFLSPCFKSDPKERPTVDDLL 1053
            M+N    K LG GAF +V +C +  +GR  A+K  +   +N        A+  EI      ++   ++ ++GI      + I MEY+ G ++   +K   +L+ SL  ++  QIL+ I  LH   I+HRDI   NI+  +Y    N KL DFG S  ++ + +        +GTP++MAPE++  E Y  K D+WSVG   V++ + + P+    P     KIA   T    P + S D  +F+    + + K RP+ D+LL
Sbjct:    1 MNNWRKGKLLGAGAFGQVYMCHDLDTGRELAVKQIETGQLNSSTKNEVKALEGEIEFMKAFRNE-RIVQYYGIETDDLHIYIFMEYLPGGSIHEHIKQHGALNESLTRKYSRQILEGILYLHTNRIVHRDIKGANILRDLYG---NVKLADFGASKRLQTIRSKT-GFRSVHGTPYWMAPEVINGEGYGRKADVWSVGCTVVEMLTTKPPWADFEPMAALFKIATQPTEPELPSDLSVDAVEFVRSTLRMNSKSRPSADELL 257
[Close]
BLAST of SMED30028687 vs. Ensembl Nematostella
Match: EDO42845 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S0A9])

HSP 1 Score: 131.339 bits (329), Expect = 7.649e-33
Identity = 90/269 (33.46%), Postives = 144/269 (53.53%), Query Frame = -2 
Query:  247 EVLKKLGIGAFAKVKLCKNKLSGRVFALK-MPKNKNINAILNEISIFSTLKSSPSMILFHGIYLHSNKLCIAMEYISGKTLESVLKDENSLDYSLKLQFVFQ-ILQQIKSLHDAGIIHRDISCNNIMIYKENQNAKLIDFGLSISVKGLNTDAIELSGKY-GTPWYMAPELLTHEPYSNKIDIWSVGVVAVKIFSGERPYTYLNPTKFQAKI-AKDKTIELDPQNFSKDVFDFLSPCFKSDPKERPTVDDLLSSKMFQINRSWQISRIS 1041
            +VL+KLG G++  V    +K SG+V A+K +P + ++  I+ EIS+      SP ++ ++G Y  +  L I MEY    ++  ++K  N      +++ V +  L+ ++ LH    IHRDI   NI++  E  +AKL DFG    V G  TD +       GTP++MAPE++    Y    DIWS+G+ A+++  G+ PY  ++P +    I  K      DP  +S+D  DF+S C   +P+ER T  +LL     Q  +  QIS +S
Sbjct:   25 DVLEKLGEGSYGSVFKAMHKESGQVVAIKQVPVDTDLQEIIKEISMMQQC-DSPYVVKYYGSYFKNTDLWIVMEYCGAGSVSDLMKIRNKTLTEEEIKCVLKYTLKGLEYLHLRRKIHRDIKAGNILLNSEG-HAKLADFG----VAGQLTDTMAKRNTVIGTPFWMAPEVIQEVGYDCLADIWSLGITAMEMAEGKPPYADIHPMRAIFMIPTKPPPTFRDPGQWSEDFKDFVSKCLVKNPEERATATELLQHSFIQGAK--QISILS 285
[Close]
BLAST of SMED30028687 vs. Ensembl Nematostella
Match: EDO31934 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SWI4])

HSP 1 Score: 125.561 bits (314), Expect = 2.634e-30
Identity = 86/277 (31.05%), Postives = 144/277 (51.99%), Query Frame = -2 
Query:  226 LKKLGIGAFAKVKLCKNKLSGRVFALKM----PKNKNINAILNEISIFSTLKSSPSMILFHGIYLHSNKLCIAMEYISGKTLESVLKDENSLDYSLKLQFVFQILQQIKSLHDAGIIHRDISCNNIMIYKENQNAKLIDFGLSISVKGLNTDAIELSGKY-GTPWYMAPELLTHEPYSNKIDIWSVGVVAVKIFSGERPYTYLNPTKFQAKIAKDKTIELDPQNFSKDVFDFLSPCFKSDPKERPTVDDLLSSKMFQINR--SWQISRISRTD*WRK 1035
            L+++G G+F +V    +  +  V A+K+         I  I  EI++ S    S  +  +HG YL   KL I MEY+ G +   ++K  N  ++ +    + ++L+ +  LH    +HRDI   N+++  E  + KL DFG    V G  TD +     + GTP++MAPE++    Y +K DIWS+G+ A+++  GE P + L+P +    I K+   EL   NFSK   +F+S C   DP +RPT  +LL  +  +  +  ++ +  I R   W++
Sbjct:   14 LERIGKGSFGEVFKGIDNRTNEVVAIKIIDLEEAEDEIEDIQQEITVLSQC-DSLYVTKYHGSYLKGTKLWIIMEYLGGGSALDLMKAGNIEEFYIA-TILREVLKGLDYLHTEKKLHRDIKAANVLM-SETGDVKLADFG----VAGQLTDTLNKRNTFVGTPFWMAPEVIKQSAYDSKADIWSLGITAIELAKGEPPNSDLHPMRVLFLIPKNNPPELT-GNFSKAFKEFVSLCLNKDPNDRPTAKELLKHRFIKTAKKNAYLVELIERHKKWKQ 282
[Close]
BLAST of SMED30028687 vs. Ensembl Nematostella
Match: EDO36150 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SJF2])

HSP 1 Score: 128.642 bits (322), Expect = 1.313e-29
Identity = 77/263 (29.28%), Postives = 136/263 (51.71%), Query Frame = -2 
Query:  277 LGIGAFAKVKLCKNKLSGRVFALKM---------PKNKNINAILNEISIFSTLKSSPSMILFHGIYLHSNKLCIAMEYISGKTLESVLKDENSLDYSLKLQFVFQILQQIKSLHDAGIIHRDISCNNIMIYKENQNAKLIDFGLSISVKGLNTDAIELSGK-YGTPWYMAPELLTHEPYSNKIDIWSVGVVAVKIFSGERPYTYLNPTKFQA---KIAKDKTIELDPQNFSKDVFDFLSPCFKSDPKERPTVDDLLSSKMFQI 1026
            LG GAF+     ++ ++G + A+K           ++K    I++EI+I + LK  P +I   G   H+    I +E+++G ++  +L      + ++ ++++ QILQ +  LH+  ++HRDI   NI++    Q+ ++ DFG +  +    T A E  G+  GT  +MAPE+L  E Y    D+WSVG V +++ +G+ P+     +   A   KIA        P++ +  V D +  C +S P++RP   DLL   +F I
Sbjct:  583 LGTGAFSSCYGARDVMTGSLMAVKQVSFCRNSKSEQDKVCQTIMDEIAILARLKH-PHLIKCLGATRHTGHFNIFLEWMAGGSISMLLSKYGPFEEAILIRYLRQILQGVSYLHENQVVHRDIKGANILVDSTGQDIRIADFGAAARLATQITGAGEFQGQLLGTIAFMAPEVLRGESYGRSCDVWSVGCVLIEMATGKPPWNAHEHSNHLALIFKIACAIGPPDIPEHLNPGVRDVVLRCLESKPEDRPAAVDLLQHPLFTI 844
[Close]
BLAST of SMED30028687 vs. Ensembl Nematostella
Match: EDO33667 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SRJ0])

HSP 1 Score: 121.324 bits (303), Expect = 3.195e-28
Identity = 78/250 (31.20%), Postives = 132/250 (52.80%), Query Frame = -2 
Query:  298 LKKLGIGAFAKVKLCKNKLSGRVFALK---MPKNKNINAILNEISIFSTLKSSPSMILFHGIYLHSNKLCIAMEYISGKTLESVLKDENSLDYSLKLQFVFQILQQIKSLHDAGIIHRDISCNNIMIYKENQNAKLIDFGLSISVKGLNTDAIELSGKYGTPWYMAPELLTHEPYSNKIDIWSVGVVAVKIFSGERPYTYLNPTKFQAKIAKDKTIEL-DPQNFSKDVFDFLSPCFKSDPKERPTVDDLL 1035
             +K+G GA   V       +G   A+K   + +      I+NEI +    K  P+++ +   YL   +L + MEY++G +L  V+  E  +D         + LQ ++ LH  G+IHRDI  +NI++  + Q  KL DFG   ++     +  + S   GTP++MAPE++T + Y  ++D+WS+G++A+++  GE PY   NP +    IA + T EL  P+  S    DFL+   + D ++R +  +LL
Sbjct:  229 FEKIGQGASGTVYTAIEVATGHEVAIKQMNLSQQPKKELIINEILVMRENKH-PNIVNYVDSYLVGEELWVVMEYLAGGSLTDVV-TETCMDEGQIAAVCRECLQALEFLHSNGVIHRDIKSDNILLGMDGQ-VKLTDFGFCATI---TPEQNKRSTMVGTPYWMAPEVVTRKQYGPRVDVWSLGIMAIEMVEGEPPYLNENPLRALYLIATNGTPELAHPEKLSPVFKDFLAQSLEMDVEKRSSARELL 472
[Close]
BLAST of SMED30028687 vs. Ensembl Medaka
Match: pak2b (p21 (RAC1) activated kinase 2 [Source:NCBI gene;Acc:101167280])

HSP 1 Score: 126.716 bits (317), Expect = 4.944e-30
Identity = 80/258 (31.01%), Postives = 140/258 (54.26%), Query Frame = -2 
Query:  271 KKLGIGAFAKVKLCKNKLSGRVFALK---MPKNKNINAILNEISIFSTLKSSPSMILFHGIYLHSNKLCIAMEYISGKTLESVLKDENSLDYSLKLQFVFQILQQIKSLHDAGIIHRDISCNNIMIYKENQNAKLIDFGLSISVKGLNTDAIELSGKYGTPWYMAPELLTHEPYSNKIDIWSVGVVAVKIFSGERPYTYLNPTKFQAKIAKDKTIEL-DPQNFSKDVFDFLSPCFKSDPKERPTVDDLLSSKMFQINR 1032
            +K+G GA   V    +  +G+  A+K   + K      I+NEI +   LK+ P+++ F   +L  ++L + MEY++G +L  V+  E  +D +       + LQ ++ LH   +IHRDI  +N+++  +  + KL DFG    +     +  + S   GTP++MAPE++T + Y  K+DIWS+G++A+++  GE PY   NP +    IA + T EL +P+  S    DFL+ C + D ++R    +LL     ++ +
Sbjct:  152 EKIGQGASGTVFTAIDVATGQEVAIKQINLQKQPKKELIINEILVMKELKN-PNIVNFLDSFLMGDELFVVMEYLAGGSLTDVVT-ETCMDEAQIAAVCRECLQALEFLHANQVIHRDIKSDNVLLGMDG-SVKLTDFGFCAQI---TPEQSKRSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMVEGEPPYLNENPLRALYLIATNGTPELQNPEKLSPVFRDFLNRCLEMDVEKRGGGKELLQHPFLKLAK 403
[Close]
BLAST of SMED30028687 vs. Ensembl Medaka
Match: ENSORLT00000015480.2 (serine/threonine-protein kinase PAK 2 [Source:NCBI gene;Acc:101169249])

HSP 1 Score: 127.102 bits (318), Expect = 8.157e-30
Identity = 81/258 (31.40%), Postives = 141/258 (54.65%), Query Frame = -2 
Query:  271 KKLGIGAFAKVKLCKNKLSGRVFALK---MPKNKNINAILNEISIFSTLKSSPSMILFHGIYLHSNKLCIAMEYISGKTLESVLKDENSLDYSLKLQFVFQILQQIKSLHDAGIIHRDISCNNIMIYKENQNAKLIDFGLSISVKGLNTDAIELSGKYGTPWYMAPELLTHEPYSNKIDIWSVGVVAVKIFSGERPYTYLNPTKFQAKIAKDKTIEL-DPQNFSKDVFDFLSPCFKSDPKERPTVDDLLSSKMFQINR 1032
            +K+G GA   V    +  +G+  A+K   + K      I+NEI +   LK+ P+++ F   +L  ++L + MEY++G +L  V+  E  +D +       ++LQ ++ LH   +IHRDI  +N+++  +  + KL DFG    +     +  + S   GTP++MAPE++T + Y  K+DIWS+G++A+++  GE PY   NP +    IA + T EL +P+  S     FLS C + D ++R +  +LL     +I +
Sbjct:  206 EKIGQGASGTVYTAIDVSTGQEVAIKQINLQKQPKKELIINEILVMKELKN-PNIVNFVDSFLVGDELFVVMEYLAGGSLTDVVT-ETCMDEAQIAAVCREVLQALEFLHANQVIHRDIKSDNVLLGMDG-SVKLTDFGFCAQI---TPEQSKRSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMVEGEPPYLNENPLRALYLIATNGTPELQNPEKLSPVFKSFLSRCLEMDVEKRGSGKELLQHPFLKIAK 457
[Close]
BLAST of SMED30028687 vs. Ensembl Medaka
Match: ENSORLT00000028689.1 (serine/threonine-protein kinase PAK 2 [Source:NCBI gene;Acc:101169249])

HSP 1 Score: 126.716 bits (317), Expect = 1.810e-29
Identity = 81/258 (31.40%), Postives = 141/258 (54.65%), Query Frame = -2 
Query:  271 KKLGIGAFAKVKLCKNKLSGRVFALK---MPKNKNINAILNEISIFSTLKSSPSMILFHGIYLHSNKLCIAMEYISGKTLESVLKDENSLDYSLKLQFVFQILQQIKSLHDAGIIHRDISCNNIMIYKENQNAKLIDFGLSISVKGLNTDAIELSGKYGTPWYMAPELLTHEPYSNKIDIWSVGVVAVKIFSGERPYTYLNPTKFQAKIAKDKTIEL-DPQNFSKDVFDFLSPCFKSDPKERPTVDDLLSSKMFQINR 1032
            +K+G GA   V    +  +G+  A+K   + K      I+NEI +   LK+ P+++ F   +L  ++L + MEY++G +L  V+  E  +D +       ++LQ ++ LH   +IHRDI  +N+++  +  + KL DFG    +     +  + S   GTP++MAPE++T + Y  K+DIWS+G++A+++  GE PY   NP +    IA + T EL +P+  S     FLS C + D ++R +  +LL     +I +
Sbjct:  243 EKIGQGASGTVYTAIDVSTGQEVAIKQINLQKQPKKELIINEILVMKELKN-PNIVNFVDSFLVGDELFVVMEYLAGGSLTDVVT-ETCMDEAQIAAVCREVLQALEFLHANQVIHRDIKSDNVLLGMDG-SVKLTDFGFCAQI---TPEQSKRSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMVEGEPPYLNENPLRALYLIATNGTPELQNPEKLSPVFKSFLSRCLEMDVEKRGSGKELLQHPFLKIAK 494
[Close]
BLAST of SMED30028687 vs. Ensembl Medaka
Match: ENSORLT00000043480.1 (serine/threonine-protein kinase PAK 2 [Source:NCBI gene;Acc:101169249])

HSP 1 Score: 126.716 bits (317), Expect = 1.810e-29
Identity = 81/258 (31.40%), Postives = 141/258 (54.65%), Query Frame = -2 
Query:  271 KKLGIGAFAKVKLCKNKLSGRVFALK---MPKNKNINAILNEISIFSTLKSSPSMILFHGIYLHSNKLCIAMEYISGKTLESVLKDENSLDYSLKLQFVFQILQQIKSLHDAGIIHRDISCNNIMIYKENQNAKLIDFGLSISVKGLNTDAIELSGKYGTPWYMAPELLTHEPYSNKIDIWSVGVVAVKIFSGERPYTYLNPTKFQAKIAKDKTIEL-DPQNFSKDVFDFLSPCFKSDPKERPTVDDLLSSKMFQINR 1032
            +K+G GA   V    +  +G+  A+K   + K      I+NEI +   LK+ P+++ F   +L  ++L + MEY++G +L  V+  E  +D +       ++LQ ++ LH   +IHRDI  +N+++  +  + KL DFG    +     +  + S   GTP++MAPE++T + Y  K+DIWS+G++A+++  GE PY   NP +    IA + T EL +P+  S     FLS C + D ++R +  +LL     +I +
Sbjct:  243 EKIGQGASGTVYTAIDVSTGQEVAIKQINLQKQPKKELIINEILVMKELKN-PNIVNFVDSFLVGDELFVVMEYLAGGSLTDVVT-ETCMDEAQIAAVCREVLQALEFLHANQVIHRDIKSDNVLLGMDG-SVKLTDFGFCAQI---TPEQSKRSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMVEGEPPYLNENPLRALYLIATNGTPELQNPEKLSPVFKSFLSRCLEMDVEKRGSGKELLQHPFLKIAK 494
[Close]
BLAST of SMED30028687 vs. Ensembl Medaka
Match: ENSORLT00000030173.1 (serine/threonine-protein kinase PAK 2 [Source:NCBI gene;Acc:101169249])

HSP 1 Score: 126.716 bits (317), Expect = 1.810e-29
Identity = 81/258 (31.40%), Postives = 141/258 (54.65%), Query Frame = -2 
Query:  271 KKLGIGAFAKVKLCKNKLSGRVFALK---MPKNKNINAILNEISIFSTLKSSPSMILFHGIYLHSNKLCIAMEYISGKTLESVLKDENSLDYSLKLQFVFQILQQIKSLHDAGIIHRDISCNNIMIYKENQNAKLIDFGLSISVKGLNTDAIELSGKYGTPWYMAPELLTHEPYSNKIDIWSVGVVAVKIFSGERPYTYLNPTKFQAKIAKDKTIEL-DPQNFSKDVFDFLSPCFKSDPKERPTVDDLLSSKMFQINR 1032
            +K+G GA   V    +  +G+  A+K   + K      I+NEI +   LK+ P+++ F   +L  ++L + MEY++G +L  V+  E  +D +       ++LQ ++ LH   +IHRDI  +N+++  +  + KL DFG    +     +  + S   GTP++MAPE++T + Y  K+DIWS+G++A+++  GE PY   NP +    IA + T EL +P+  S     FLS C + D ++R +  +LL     +I +
Sbjct:  243 EKIGQGASGTVYTAIDVSTGQEVAIKQINLQKQPKKELIINEILVMKELKN-PNIVNFVDSFLVGDELFVVMEYLAGGSLTDVVT-ETCMDEAQIAAVCREVLQALEFLHANQVIHRDIKSDNVLLGMDG-SVKLTDFGFCAQI---TPEQSKRSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMVEGEPPYLNENPLRALYLIATNGTPELQNPEKLSPVFKSFLSRCLEMDVEKRGSGKELLQHPFLKIAK 494
[Close]
BLAST of SMED30028687 vs. Planmine SMEST
Match: SMESG000003172.1 (SMESG000003172.1)

HSP 1 Score: 556.599 bits (1433), Expect = 1.528e-174
Identity = 270/272 (99.26%), Postives = 271/272 (99.63%), Query Frame = -2 
Query:  238 MDNIEVLKKLGIGAFAKVKLCKNKLSGRVFALKMPKNKNINAILNEISIFSTLKSSPSMILFHGIYLHSNKLCIAMEYISGKTLESVLKDENSLDYSLKLQFVFQILQQIKSLHDAGIIHRDISCNNIMIYKENQNAKLIDFGLSISVKGLNTDAIELSGKYGTPWYMAPELLTHEPYSNKIDIWSVGVVAVKIFSGERPYTYLNPTKFQAKIAKDKTIELDPQNFSKDVFDFLSPCFKSDPKERPTVDDLLSSKMFQINRSWQISRISRTD 1053
            MDNIEVLKKLGIGAFAKVKLCKNKLSGRVFALKMPKNKNINAILNEISIFSTLKSSPSMILFHGIYLHSNKLCIAMEYISGKTLESVLKDENSLDYSLKLQFVFQILQQIKSLHDAGIIHRDISCNNIMIYKENQNAKLIDFGLSISVKGLNTDAIELSGKYGTPWYMAPELLTHEPYSNKIDIWSVGVVAVKIFSG+RPYTYLNPTKFQAKIAKDKTIELDPQ FSKDVFDFLSPCFKSDPKERPTVDDLLSSKMFQINRSWQISRISRTD
Sbjct:  452 MDNIEVLKKLGIGAFAKVKLCKNKLSGRVFALKMPKNKNINAILNEISIFSTLKSSPSMILFHGIYLHSNKLCIAMEYISGKTLESVLKDENSLDYSLKLQFVFQILQQIKSLHDAGIIHRDISCNNIMIYKENQNAKLIDFGLSISVKGLNTDAIELSGKYGTPWYMAPELLTHEPYSNKIDIWSVGVVAVKIFSGKRPYTYLNPTKFQAKIAKDKTIELDPQKFSKDVFDFLSPCFKSDPKERPTVDDLLSSKMFQINRSWQISRISRTD 723

HSP 2 Score: 136.732 bits (343), Expect = 4.619e-32
Identity = 66/72 (91.67%), Postives = 68/72 (94.44%), Query Frame = -2 
Query: 3952 PSIEWQTTDDNFDIINLPKHIFAVGNLKKEISRQLGENKDNLRLITDGETQSDDDYVIDLNDVHYCRIIIML 4167
            PSIEWQTTDDNFDIINLPKHIF VGNLK+EISRQLGENKDNLRLI DGETQSDDDYVIDLND + CRIIIML
Sbjct:  379 PSIEWQTTDDNFDIINLPKHIFTVGNLKEEISRQLGENKDNLRLIKDGETQSDDDYVIDLNDANDCRIIIML 450
[Close]
BLAST of SMED30028687 vs. Planmine SMEST
Match: SMESG000003172.1 (SMESG000003172.1)

HSP 1 Score: 555.058 bits (1429), Expect = 2.883e-174
Identity = 270/272 (99.26%), Postives = 271/272 (99.63%), Query Frame = -2 
Query:  238 MDNIEVLKKLGIGAFAKVKLCKNKLSGRVFALKMPKNKNINAILNEISIFSTLKSSPSMILFHGIYLHSNKLCIAMEYISGKTLESVLKDENSLDYSLKLQFVFQILQQIKSLHDAGIIHRDISCNNIMIYKENQNAKLIDFGLSISVKGLNTDAIELSGKYGTPWYMAPELLTHEPYSNKIDIWSVGVVAVKIFSGERPYTYLNPTKFQAKIAKDKTIELDPQNFSKDVFDFLSPCFKSDPKERPTVDDLLSSKMFQINRSWQISRISRTD 1053
            MDNIEVLKKLGIGAFAKVKLCKNKLSGRVFALKMPKNKNINAILNEISIFSTLKSSPSMILFHGIYLHSNKLCIAMEYISGKTLESVLKDENSLDYSLKLQFVFQILQQIKSLHDAGIIHRDISCNNIMIYKENQNAKLIDFGLSISVKGLNTDAIELSGKYGTPWYMAPELLTHEPYSNKIDIWSVGVVAVKIFSG+RPYTYLNPTKFQAKIAKDKTIELDPQ FSKDVFDFLSPCFKSDPKERPTVDDLLSSKMFQINRSWQISRISRTD
Sbjct:  434 MDNIEVLKKLGIGAFAKVKLCKNKLSGRVFALKMPKNKNINAILNEISIFSTLKSSPSMILFHGIYLHSNKLCIAMEYISGKTLESVLKDENSLDYSLKLQFVFQILQQIKSLHDAGIIHRDISCNNIMIYKENQNAKLIDFGLSISVKGLNTDAIELSGKYGTPWYMAPELLTHEPYSNKIDIWSVGVVAVKIFSGKRPYTYLNPTKFQAKIAKDKTIELDPQKFSKDVFDFLSPCFKSDPKERPTVDDLLSSKMFQINRSWQISRISRTD 705

HSP 2 Score: 136.732 bits (343), Expect = 4.498e-32
Identity = 66/72 (91.67%), Postives = 68/72 (94.44%), Query Frame = -2 
Query: 3952 PSIEWQTTDDNFDIINLPKHIFAVGNLKKEISRQLGENKDNLRLITDGETQSDDDYVIDLNDVHYCRIIIML 4167
            PSIEWQTTDDNFDIINLPKHIF VGNLK+EISRQLGENKDNLRLI DGETQSDDDYVIDLND + CRIIIML
Sbjct:  361 PSIEWQTTDDNFDIINLPKHIFTVGNLKEEISRQLGENKDNLRLIKDGETQSDDDYVIDLNDANDCRIIIML 432
[Close]
BLAST of SMED30028687 vs. Planmine SMEST
Match: SMESG000003172.1 (SMESG000003172.1)

HSP 1 Score: 459.914 bits (1182), Expect = 1.337e-141
Identity = 221/226 (97.79%), Postives = 223/226 (98.67%), Query Frame = -2 
Query:  238 ISIFSTLKSSPSMILFHGIYLHSNKLCIAMEYISGKTLESVLKDENSLDYSLKLQFVFQILQQIKSLHDAGIIHRDISCNNIMIYKENQNAKLIDFGLSISVKGLNTDAIELSGKYGTPWYMAPELLTHEPYSNKIDIWSVGVVAVKIFSGERPYTYLNPTKFQAKIAKDKTIELDPQNFSKDVFDFLSPCFKSDPKERPTVDDLLSSKMFQINRSWQISRISRTD 915
            I + STLKSSPSMILFHGIYLHSNKLCIAMEYISGKTLESVLKDENSLDYSLKLQFVFQILQQIKSLHDAGIIHRDISCNNIMIYKENQNAKLIDFGLSISVKGLNTDAIELSGKYGTPWYMAPELLTHEPYSNKIDIWSVGVVAVKIFSG+RPYTYLNPTKFQAKIAKDKTIELDPQ FSKDVFDFLSPCFKSDPKERPTVDDLLSSKMFQINRSWQISRISRTD
Sbjct:  447 IIMLSTLKSSPSMILFHGIYLHSNKLCIAMEYISGKTLESVLKDENSLDYSLKLQFVFQILQQIKSLHDAGIIHRDISCNNIMIYKENQNAKLIDFGLSISVKGLNTDAIELSGKYGTPWYMAPELLTHEPYSNKIDIWSVGVVAVKIFSGKRPYTYLNPTKFQAKIAKDKTIELDPQKFSKDVFDFLSPCFKSDPKERPTVDDLLSSKMFQINRSWQISRISRTD 672

HSP 2 Score: 136.732 bits (343), Expect = 3.679e-32
Identity = 66/72 (91.67%), Postives = 68/72 (94.44%), Query Frame = -2 
Query: 3952 PSIEWQTTDDNFDIINLPKHIFAVGNLKKEISRQLGENKDNLRLITDGETQSDDDYVIDLNDVHYCRIIIML 4167
            PSIEWQTTDDNFDIINLPKHIF VGNLK+EISRQLGENKDNLRLI DGETQSDDDYVIDLND + CRIIIML
Sbjct:  379 PSIEWQTTDDNFDIINLPKHIFTVGNLKEEISRQLGENKDNLRLIKDGETQSDDDYVIDLNDANDCRIIIML 450
[Close]
BLAST of SMED30028687 vs. Planmine SMEST
Match: SMESG000003172.1 (SMESG000003172.1)

HSP 1 Score: 459.144 bits (1180), Expect = 2.928e-141
Identity = 221/226 (97.79%), Postives = 223/226 (98.67%), Query Frame = -2 
Query:  238 ISIFSTLKSSPSMILFHGIYLHSNKLCIAMEYISGKTLESVLKDENSLDYSLKLQFVFQILQQIKSLHDAGIIHRDISCNNIMIYKENQNAKLIDFGLSISVKGLNTDAIELSGKYGTPWYMAPELLTHEPYSNKIDIWSVGVVAVKIFSGERPYTYLNPTKFQAKIAKDKTIELDPQNFSKDVFDFLSPCFKSDPKERPTVDDLLSSKMFQINRSWQISRISRTD 915
            I + STLKSSPSMILFHGIYLHSNKLCIAMEYISGKTLESVLKDENSLDYSLKLQFVFQILQQIKSLHDAGIIHRDISCNNIMIYKENQNAKLIDFGLSISVKGLNTDAIELSGKYGTPWYMAPELLTHEPYSNKIDIWSVGVVAVKIFSG+RPYTYLNPTKFQAKIAKDKTIELDPQ FSKDVFDFLSPCFKSDPKERPTVDDLLSSKMFQINRSWQISRISRTD
Sbjct:  457 IIMLSTLKSSPSMILFHGIYLHSNKLCIAMEYISGKTLESVLKDENSLDYSLKLQFVFQILQQIKSLHDAGIIHRDISCNNIMIYKENQNAKLIDFGLSISVKGLNTDAIELSGKYGTPWYMAPELLTHEPYSNKIDIWSVGVVAVKIFSGKRPYTYLNPTKFQAKIAKDKTIELDPQKFSKDVFDFLSPCFKSDPKERPTVDDLLSSKMFQINRSWQISRISRTD 682

HSP 2 Score: 136.346 bits (342), Expect = 4.465e-32
Identity = 66/72 (91.67%), Postives = 68/72 (94.44%), Query Frame = -2 
Query: 3952 PSIEWQTTDDNFDIINLPKHIFAVGNLKKEISRQLGENKDNLRLITDGETQSDDDYVIDLNDVHYCRIIIML 4167
            PSIEWQTTDDNFDIINLPKHIF VGNLK+EISRQLGENKDNLRLI DGETQSDDDYVIDLND + CRIIIML
Sbjct:  389 PSIEWQTTDDNFDIINLPKHIFTVGNLKEEISRQLGENKDNLRLIKDGETQSDDDYVIDLNDANDCRIIIML 460
[Close]
BLAST of SMED30028687 vs. Planmine SMEST
Match: SMESG000003172.1 (SMESG000003172.1)

HSP 1 Score: 459.529 bits (1181), Expect = 3.201e-141
Identity = 221/226 (97.79%), Postives = 223/226 (98.67%), Query Frame = -2 
Query:  238 ISIFSTLKSSPSMILFHGIYLHSNKLCIAMEYISGKTLESVLKDENSLDYSLKLQFVFQILQQIKSLHDAGIIHRDISCNNIMIYKENQNAKLIDFGLSISVKGLNTDAIELSGKYGTPWYMAPELLTHEPYSNKIDIWSVGVVAVKIFSGERPYTYLNPTKFQAKIAKDKTIELDPQNFSKDVFDFLSPCFKSDPKERPTVDDLLSSKMFQINRSWQISRISRTD 915
            I + STLKSSPSMILFHGIYLHSNKLCIAMEYISGKTLESVLKDENSLDYSLKLQFVFQILQQIKSLHDAGIIHRDISCNNIMIYKENQNAKLIDFGLSISVKGLNTDAIELSGKYGTPWYMAPELLTHEPYSNKIDIWSVGVVAVKIFSG+RPYTYLNPTKFQAKIAKDKTIELDPQ FSKDVFDFLSPCFKSDPKERPTVDDLLSSKMFQINRSWQISRISRTD
Sbjct:  465 IIMLSTLKSSPSMILFHGIYLHSNKLCIAMEYISGKTLESVLKDENSLDYSLKLQFVFQILQQIKSLHDAGIIHRDISCNNIMIYKENQNAKLIDFGLSISVKGLNTDAIELSGKYGTPWYMAPELLTHEPYSNKIDIWSVGVVAVKIFSGKRPYTYLNPTKFQAKIAKDKTIELDPQKFSKDVFDFLSPCFKSDPKERPTVDDLLSSKMFQINRSWQISRISRTD 690

HSP 2 Score: 136.732 bits (343), Expect = 4.054e-32
Identity = 66/72 (91.67%), Postives = 68/72 (94.44%), Query Frame = -2 
Query: 3952 PSIEWQTTDDNFDIINLPKHIFAVGNLKKEISRQLGENKDNLRLITDGETQSDDDYVIDLNDVHYCRIIIML 4167
            PSIEWQTTDDNFDIINLPKHIF VGNLK+EISRQLGENKDNLRLI DGETQSDDDYVIDLND + CRIIIML
Sbjct:  397 PSIEWQTTDDNFDIINLPKHIFTVGNLKEEISRQLGENKDNLRLIKDGETQSDDDYVIDLNDANDCRIIIML 468
The following BLAST results are available for this feature:
BLAST of SMED30028687 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
PAK24.706e-3031.78p21 (RAC1) activated kinase 2 [Source:HGNC Symbol;... [more]
PAK15.831e-3033.33p21 (RAC1) activated kinase 1 [Source:HGNC Symbol;... [more]
NEK51.705e-2931.03NIMA related kinase 5 [Source:HGNC Symbol;Acc:HGNC... [more]
PAK13.506e-2931.27p21 (RAC1) activated kinase 1 [Source:HGNC Symbol;... [more]
STK244.383e-2932.85serine/threonine kinase 24 [Source:HGNC Symbol;Acc... [more]
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BLAST of SMED30028687 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
cst-21.026e-2730.92Caenorhabditis STE20-like kinase [Source:UniProtK... [more]
cst-12.651e-2730.92Serine/threonine-protein kinase cst-1 Serine/threo... [more]
cst-12.788e-2730.92Serine/threonine-protein kinase cst-1 Serine/threo... [more]
gck-13.847e-2731.60Germinal center kinase 1 [Source:UniProtKB/Swiss-... [more]
gck-14.253e-2731.60Germinal center kinase 1 [Source:UniProtKB/Swiss-... [more]
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BLAST of SMED30028687 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Mekk12.558e-3232.70gene:FBgn0024329 transcript:FBtr0331353[more]
Mekk12.694e-3232.70gene:FBgn0024329 transcript:FBtr0083684[more]
GckIII1.442e-2530.00gene:FBgn0266465 transcript:FBtr0083399[more]
Slik1.716e-2530.86gene:FBgn0035001 transcript:FBtr0332925[more]
Slik1.919e-2530.86gene:FBgn0035001 transcript:FBtr0072363[more]
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BLAST of SMED30028687 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
dapk2a1.096e-2931.54death-associated protein kinase 2a [Source:ZFIN;Ac... [more]
stk24b3.198e-2933.33serine/threonine kinase 24b (STE20 homolog, yeast)... [more]
stk24b3.881e-2933.20serine/threonine kinase 24b (STE20 homolog, yeast)... [more]
pak2a6.805e-2931.01p21 protein (Cdc42/Rac)-activated kinase 2a [Sourc... [more]
pak2a6.805e-2931.01p21 protein (Cdc42/Rac)-activated kinase 2a [Sourc... [more]
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BLAST of SMED30028687 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
stk256.563e-3132.08serine/threonine kinase 25 [Source:NCBI gene;Acc:5... [more]
stk251.899e-3034.12serine/threonine kinase 25 [Source:NCBI gene;Acc:5... [more]
stk252.768e-3034.25serine/threonine kinase 25 [Source:NCBI gene;Acc:5... [more]
stk253.006e-3034.25serine/threonine kinase 25 [Source:NCBI gene;Acc:5... [more]
slc39a79.482e-2933.46solute carrier family 39 member 7 [Source:Xenbase;... [more]
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BLAST of SMED30028687 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Pak23.571e-3031.78p21 (RAC1) activated kinase 2 [Source:MGI Symbol;A... [more]
Nek51.317e-2932.42NIMA (never in mitosis gene a)-related expressed k... [more]
Nek51.884e-2932.42NIMA (never in mitosis gene a)-related expressed k... [more]
Pak15.059e-2930.89p21 (RAC1) activated kinase 1 [Source:MGI Symbol;A... [more]
Pak15.059e-2930.89p21 (RAC1) activated kinase 1 [Source:MGI Symbol;A... [more]
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BLAST of SMED30028687 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|P38692|KIC1_YEAST1.735e-2931.30Serine/threonine-protein kinase KIC1 OS=Saccharomy... [more]
sp|Q13177|PAK2_HUMAN2.260e-2931.78Serine/threonine-protein kinase PAK 2 OS=Homo sapi... [more]
sp|Q29502|PAK2_RABIT2.302e-2931.78Serine/threonine-protein kinase PAK 2 OS=Oryctolag... [more]
sp|O61122|SVKA_DICDI2.354e-2933.20Serine/threonine-protein kinase svkA OS=Dictyostel... [more]
sp|Q8CIN4|PAK2_MOUSE2.498e-2931.78Serine/threonine-protein kinase PAK 2 OS=Mus muscu... [more]
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BLAST of SMED30028687 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A0P4WAY34.845e-3732.44Protein kinase domain-containing protein OS=Scylla... [more]
A0A371IGI63.558e-3538.15Mitogen-activated protein kinase kinase kinase NPK... [more]
A0A445DK241.821e-3335.34Protein kinase domain-containing protein OS=Arachi... [more]
A0A444ZC672.040e-3335.34Protein kinase domain-containing protein OS=Arachi... [more]
A0A0C3LVR52.751e-3332.61Protein kinase domain-containing protein OS=Tulasn... [more]
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BLAST of SMED30028687 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
pak2b1.058e-2931.01p21 protein (Cdc42/Rac)-activated kinase 2b [Sourc... [more]
stk24b1.280e-2933.20serine/threonine-protein kinase 24-like [Source:NC... [more]
ENSAMXT00000008518.21.799e-2932.13pep primary_assembly:Astyanax_mexicanus-2.0:19:145... [more]
stk17b1.941e-2929.66serine/threonine kinase 17b [Source:NCBI gene;Acc:... [more]
STK41.961e-2931.78serine/threonine kinase 4 [Source:HGNC Symbol;Acc:... [more]
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BLAST of SMED30028687 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5
Match NameE-valueIdentityDescription
map3k21.297e-2729.85mitogen-activated protein kinase kinase kinase 2 [... [more]
stk25a1.450e-2532.56serine/threonine kinase 25a [Source:ZFIN;Acc:ZDB-G... [more]
slka1.562e-2532.67STE20-like kinase a [Source:ZFIN;Acc:ZDB-GENE-0504... [more]
map3k192.939e-2526.89mitogen-activated protein kinase kinase kinase 19 ... [more]
NEK98.993e-2529.03NIMA related kinase 9 [Source:HGNC Symbol;Acc:HGNC... [more]
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BLAST of SMED30028687 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 5
Match NameE-valueIdentityDescription
KIC12.498e-3131.30Protein kinase of the PAK/Ste20 family, required f... [more]
BCK12.665e-2830.86MAPKKK acting in the protein kinase C signaling pa... [more]
TPK27.379e-2727.20cAMP-dependent protein kinase catalytic subunit; p... [more]
CDC157.118e-2632.39Protein kinase of the Mitotic Exit Network; locali... [more]
MKK22.118e-2530.88MAPKK involved in the protein kinase C signaling p... [more]
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BLAST of SMED30028687 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO414102.829e-3431.30Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO428457.649e-3333.46Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO319342.634e-3031.05Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO361501.313e-2929.28Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO336673.195e-2831.20Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of SMED30028687 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
pak2b4.944e-3031.01p21 (RAC1) activated kinase 2 [Source:NCBI gene;Ac... [more]
ENSORLT00000015480.28.157e-3031.40serine/threonine-protein kinase PAK 2 [Source:NCBI... [more]
ENSORLT00000028689.11.810e-2931.40serine/threonine-protein kinase PAK 2 [Source:NCBI... [more]
ENSORLT00000043480.11.810e-2931.40serine/threonine-protein kinase PAK 2 [Source:NCBI... [more]
ENSORLT00000030173.11.810e-2931.40serine/threonine-protein kinase PAK 2 [Source:NCBI... [more]
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BLAST of SMED30028687 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000003172.11.528e-17499.26SMESG000003172.1[more]
SMESG000003172.12.883e-17499.26SMESG000003172.1[more]
SMESG000003172.11.337e-14197.79SMESG000003172.1[more]
SMESG000003172.12.928e-14197.79SMESG000003172.1[more]
SMESG000003172.13.201e-14197.79SMESG000003172.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30028687 ID=SMED30028687|Name=SMED30028687|organism=Schmidtea mediterranea sexual|type=transcript|length=8551bp
GTCAAATTTTGTAGAAAATATTATATAATGTATACATTATTATAATTAAA
GTTGTGTTCTAACTTATGTCAATGCAACAATGCTCATATGGGTTTTGTGA
TGAATTTCATTACCAAAGTCATTAGCAATTCTAGTTTAAGATTCACAGTA
ATTATCATCAAGATTTAAAACCGATTATGAATTAATAATTCCTTCATGAT
CACTCCCAGAACAAATAAATGCAGCCTTTCTCCACTAGTCAGTTCGTGAA
ATTCTGGAAATTTGCCATGAACGATTAATTTGGAACATCTTTGAACTTAG
CAAATCATCAACTGTAGGTCTTTCTTTAGGATCTGATTTGAAACATGGAC
TTAGGAAATCAAAAACGTCTTTGGAAAAATTTTGTGGATCTAATTCAATA
GTTTTATCTTTGGCAATTTTTGCTTGAAATTTAGTTGGGTTTAGGTAGGT
ATATGGGCGTTCTCCGGAAAATATTTTGACAGCAACAACACCAACAGACC
AAATATCAATTTTGTTCGAGTAAGGTTCATGAGTTAACAACTCAGGAGCC
ATATACCAAGGTGTACCATATTTACCAGATAATTCTATAGCATCTGTATT
CAATCCTTTTACAGATATTGAAAGCCCAAAGTCAATTAATTTTGCATTTT
GATTCTCCTTGTAAATCATAATGTTATTACATGAGATATCTCGGTGAATA
ATTCCAGCATCATGGAGAGATTTTATTTGCTGTAAAATCTGAAACACAAA
TTGTAATTTTAAAGAATAGTCTAAACTGTTTTCATCTTTCAAAACAGATT
CTAGTGTTTTCCCAGAAATGTATTCCATCGCAATGCACAGCTTATTTGAA
TGCAAGTATATCCCATGAAATAATATCATAGATGGCGAAGATTTCAATGT
ACTAAAAATTGAAATTTCATTCAAAATTGCATTGATATTTTTATTTTTAG
GCATTTTTAGTGCAAATACTCGACCTGATAACTTATTTTTGCATAGCTTT
ACTTTTGCAAACGCACCAATTCCAAGTTTCTTTAGGACTTCTATATTATC
CATACTAAAAAGTTTATTTTAAAATGATTTAGAATTAAAATTTGATTTTA
ATTTTAAAATATAATACGGTTATCAAAAATATTCTAGCCCAAGAAAAAGA
GACATTGCATATTCGTTTACAAGGCAATGCAAGAGGGGAACCACAAAACC
CACAAAACATAGAATAGTAATTAAATATGTTACAAACGAAAGAATAGCAT
AAAGTACGTTGATTAAGAAACACTTGTATTCAATGATTTTCAAAATTGAA
TCAATGAGAAATTTGTCAAATATTGGATAAGAACTAAATATAGTTGAAAG
GTATTCGCGTATATTTATTGAAATGTTTATAATAAAGAAACTTTATGAGA
AGAATATTTTCGAAACGATATAAAAAGTATAGTAAAAACTAAAAAAAAGC
AGTGAATTTAATTAAAAAAGACGTCTAATCAAAAGAATCTGAACAAGATA
GGCATGTTCTTAGATCAACTAATTTATTGCATCACTGTACTCCCGACATG
GAACAGATAAAAATATAAAACAGTAATAAGCTGTTTCCTGAAACACCTGC
TTTTGAGAAACCCTACATGAGAGTAGACAATAATACAATAGAAAGACTAA
AAGAAGAAATAAAGTAAATAAATGCAGTTAAGAAAAATTATTAAGAATGA
AAAATAGGTTCAAATATCAAATTTCAAGAAAAATATGACTTAATATAACT
AGTAATAATAGCGAGTCAACCAAATGTAAGAACTACTAAGCATCATAGCG
CAAAAAACTACTCTGGCATACAAACCAGAGAAATGTGGTTACAGAACCAA
CTCATAAGGATTGGAAAATAAAATATGTATTAACGGAAAAGAAATTAAAA
ACATCAGTGGCGAAAATAGATATACTTACGTTGGAAATAGAATTGGAAAC
AAGAACAAAAACACATAAACGAAACATTTAATGATATTCGAAGAAAGATG
AAGAACATATTTGAGTTCAAAATCCAATGCGAAGTATTTACCATAATTGG
ACACTCAAAACTCATCTTTCAATTACAAGTCGAAGACGTAGAAAAAACTG
ATATTGACCAATTCGACAAAGACAAATCAAAAAATGCCATAAACCTTCCT
GGCAAACGCCTCTTTATGGATGTAATAATATACTCACCTAAAGAAGAAAG
AGGTCTAGGTATAACTAAAACCATATTAGAGCAAGCAGCCCAATCAATTA
ACAGAATAATGCAGCTCATCAACAACAGCCATGCTTCAATAGTAAAAATC
ATAATAGATATAGCTAAGATAAGTACTAAACATTCGATCACTAACCTAAA
GAAAGAACTAAAATGATTAGATGGAACCTATGAAAATAAGCCCAAGAAAA
GCCGCAAATCCACATGACTCAACAGAGTCAGGGGTACATTACAAAAATTA
TGAAACAATTATCATATAAAGTTGTGTCCAAAAACCAAGAGCGAAAAGCT
GGGATGCATTATAAAATGAGGAACCCAAGAAAGCATTTACACACTAGACT
ATCAAGCAACAAAGGATCTACCAAAAACCCTACACTGAATGATAAAGGAG
AGGTATACAGAAAAATTATGGAATTAAGCAATTTTTCAAGATCTAGTTCT
AAACCTACCAAACTCAGAACAAATGAAATGGAAAATACTTCCTAACCTCA
AGGATCCAGAATGGCATTTCATCATAATAGCAATATTCAATAACCTTGAT
TTGAATATGAAACAAGTTAACCAATGAGGTAGAATAGAATACACTGCTTC
ACAAAAGAATTATTGGCACATGTGATCAATTATCATCTTAGATATCAAAC
GCCATTCTATGACAAAGAAGCACTAGAAGCCGTGAACAAGAATTATGATA
AATACAGCGAGCTAAGAAGAGACATGTATTTACACAATTGTCGAAACTTT
TATGGTGTGCTCTCTCGGAGCATTGGATAAAAGAAACTCCATACTAAGAA
ATCTTAAGATCAAATACCAAGAATATCAGTTACGAAAGCAAAAATGTTTA
AGGGTGCCATCAAAGGCTCTAGGAAGATCTAGAAAACCACAGATGATATT
TCACATAGCCGCGATTAGAAAAAGGATATTCTATGGAAAAATCCATAAAG
AAGGCATACTTGTGATAAATAGTATCCAGATATATAGATTGTCTAATATC
TTTGGGCCAACAATCCATGTACTGTTTTTGAATTGTTTAAATAATAAATA
TTGAGGTTCCCAGAATCTTAACTAGATGTCTTATATAAATAAGAACACTA
ACACTGGTTCAAAGACTTTTATTTAAATACCACACTTATACAACAAAGAT
GTTAACCTTCACTAGCTTTTAATAATTACTCTATCTTCTTATTGTGTTTC
CTGTGCTAACTCTATTTGCAGTTGCCTGAGATCTGCTACGTAATTTTTGT
AATTGGCTTAATTTTTATTTGTAAATTTGTTTATAATGTCAATAAATCAC
CTAACGACTTTTGGAAATATTCCATTTAAAGTTAATAAACATGTTAAAAA
GCTTTGGTTTATGAAATTTTAATAAAATATTGAGATATATTAATATAAAA
GTATTGAATTTATTTAATTTTTGTTTATTGATATACTATTTATACATTGC
CAGTAATCTATAATAATAAAATAATACATTTTAAATATTTAAATTACTAA
AAATTTTCTTTTATTTATCATTATAAATCCTTAACATATATATTTACTAA
TGTACGTAACTAATGCCTGTAACTTTGTTAACTATGGCATAGTCACGTAT
ATCAACACTATTATATATACAAAATTCTCATACAACTGTTATTATAAATT
ATGTCAGTACATCAGGTGATTTTTCACGGGTCAAATAATTCACTATTCAA
ATATATCTAAGGAGAAGGAAAACCTAAATTTTATATAAACCAAAATTACC
TTAACATAATAATTATACGACAGTAATGTACATCATTCAAATCTATTACA
TAATCATCGTCGGATTGCGTTTCTCCATCCGTTATCAAACGTAAATTGTC
TTTATTTTCACCCAGCTGCCTAGAAATTTCTTTCTTTAAGTTTCCAACAG
CGAAAATATGTTTGGGCAGATTAATAATATCAAAATTATCATCTGTTGTT
TGCCATTCTATTGATGGACTGAAGCAAAGTCATAAATACAGATTAAAAGA
AAGCGATTAAAATGATTAAATTAACTAACTGGCAACTCGACAAAATAAAT
ATCGATTCAAACAATTATGTTTGGAACCTTGGATTCATCACATTTTAATT
TATTGGTATCACTTTTATTGGATATTAGTAGGTAGAAACCTCTTTTACAA
AGACTAATAAATTCAGAAATGAACATATGCATAAAGACTATTTTCATTTA
TTCATATTTTCGACTATTGCCTATGGCATTTCATGCGAACTGCTAATCCC
AACAACTCATACTTTTTTACTGATGGTCAACAACCAAATATATTCCAAAC
ATACTTATTTTATATCATAAAATCAAAACCCACACAAAACTTGAGTGAAT
CTTTAAACAAATGCTGTTTCGCGAGTTCAGTGAATAATAGAAGTTTATCA
TATTATTTTGTGATGATTAAAATTAAATAGTTACTAATTTTAAGAAAAAA
AAAAGGTTACAAATTTTGAAAATATTGGATTCCCCCACCCTTCAAAAACA
CGAGCGCTTATCTTTGTCATTTTGCGAAGAGTCTTTTTTATGCGCTGTCA
TATCTCAAACAATAAGCCATAACAGATTCCTCAACATCTTCTTTAACTTG
GCTCAAAACCGATCCAATAGCTCTACCTTCTCTTGGATAGTCGAGAATAG
GTGCCTCACAAAACCTATCATTCAGTGATAGGAAGTTTTCATTACATTCT
TTAGCCCAAATTATATCTTTATCACATCCAGATGTTGCGATATAATATCG
TTCTGCGATTTTGGCATAGTCTTTGGTGAATCTTTTGTAGTATTTCATTT
ATCAGAGAAAGGAGCTTTACTGATTCGAACATTTTGGTACTTCTGTTTTT
TCAATTTCTTTAACTTTCTTTCTATTTATTTGAATAACCCTTTCTGTTAA
CTGTATGCACAAGGAAGCAAAATTCTGTTTTATTGAATTCACAGTTTTGT
GTTTATCTTCAACCTTGCCATTTGAATTGTTTTAAATATTTCTTTTATTA
GCTCATCGTGATCTTTTTTGCTTTTCTCGTATATTAAAATATCATCTAAG
TAAACTACTACTATTAATTGTATTCTTTCCAATACTGTGTGAACTAGTCG
CTGAAATGTAACAGAAGCGATTGCTAATCAAAACGGTAGCCTATTGAAAC
AAATTTTCATTTCTCTTGTAGTAAATCTACTCATTCCTTGAATATCTAGA
GTAAGTTATATTGGTAATACGCCTGATCTAAATCAATTGACGAAAATAAT
CTTGCAACCAAAAGACAGTACAATAAAAAATTGATATTAGGCATCTGTAA
AGATTCCTTTTCCATTATATGGTATAGAAACATTGTGATTATTTCTTATT
TTCGGCGTGATCGCCAGTTAAATCCAACTCATTTTTAAAAGAATTTAATT
CCGCTAAGATATATTTCATAAAAGTGCTAAATAAACAATTATTTAAACAC
AAGATAATTATATATCTTAACTCTCTCCTTAATATTTTCCTGTTTTGATG
CTCAAGAAATTTGAAGCATATGCTTCGTTATTTATGAATAAAAATGGCCT
TGTGATCAGGAGCAAATGCTCACAGTACTTCCTCATGAGCATTTGCTCTG
GAAACCTTGAGCACATGCTTCATGCTCTTAACCACATGCTCTGATTTTTG
AGCATATGCTCTTAAAAACCTGAGATTGGTTAGGAGCAACCTCATATTTT
ATTTATGCTGTTACAACACTCTAAAAAAGGTGGCGCATAAACGTAATTGA
ATTTATCAAGTTCCCTATAACATTTGAGAAAAATATGGAAAATAGAGCAA
AGTGGACTGCTGCTAGGGGATATTCTGCAATCATCGGTGCATTAGACTGT
ACGCATGTGAGAATTGAAAAACCAAGTGGCGTTCATGGTGACGAGTACAT
CAACAGGAAAGGGTTTCCTTCTTTAAATGCCCAGGTAAGCTGTAACTGTT
GAAACCTTTATATTTGTTGTTAAATGTCTGGACTTGTTTATCAGGCCACT
TGTAATGAAAAATGCTTGCTGGCCTGGGTTAGTACATGATAATTGTGACC
TGAAAAATATTCATATTTTAATAAGTCAAAGAAGGGAAACATCCGAAATG
ATTAACCGCAAAACTCTTCAGTAACCAATCAGCAGTTTTCTGTGTGTGAT
TGTGTGTGAGAGAGTGCTTTTATTTATCTCAGCGCAGCTTGGTGTACCGT
TATGGCGTAGCACATGCTCACGAGAATAAGCATGTACTCGGTAGTATGAG
CAATAGGTTATTAATAAACCTTAGAGTACATGCTTATGCACTTGAACACA
TGCTCACACCCTAATGCTCATACTCAAGGCATTTGCTCCATGAGCACATG
ATCAACTTTATTCATACGGCCCATTCTTTTAGTCTTTTTATATCTTAATC
AGAAATACCATGTCTCAAATATAGAACCTGTAGTAAAAAATTATGTGTTT
CGGATTTAAATTGTTTCACTTGATTTGGCAATCTTCCAAGCACCGCTCTT
ACTCTTCCTAGTTGTTGTTCATATGTACCTCCATATATCAAAACATTGTC
AATGTATATCAAACATTGTTCACGCTTTTCTTTTTAAAAATCATATCCAT
CAATCTTTGAAAAGTAGCCGGTGCTGTAGACAGTCCGATCGACATTCTGC
TAAATCCAAATAGTCTTCTCTTTATCAACTTCTTTTAGCTAGAAATTATA
AAATCCATTTGACAAATCTAAAACGCTGAACACTGTTAGTATACAAGGAA
ACTAAAATTCAAATTATGACACACTAACATAATCTATTATTGCCATTTTC
CGTCTCTTGAGTTTTCAGGGTCATATATTTTCCCTCGCACACCTCACAAT
TTCCCACTTCACTGTCATCTACCCATGAGCGAACCCACCTTGGTACCGCA
CATGACTTCCGTAAACTATTCGAGAAGGTGAGCACCGTTTCCGGTACTAC
TCCTCGAATAACACTCGTTACGGGTTCCAGACAGCCGCTAGAAGGTCCTA
CGTCGACATGGCTTTCCTGGGTGAACTGAATTCCCATCGGTTCCATGCAT
ATACTTGTAGAAAATTTTCGTATTCAAATCGGTACTTAGTAAATTTTCCT
TTTGTTTAGAAATTTTCTACCGTTGGGGCAAAGTCGTAAAAATTATGTGA
TTTGAACTAATATGTACTACTTGAGTAAAATATTAGGAAAATAAACTTTA
ACCCCATTTTATTACAAAAGACTATTTCATTTCAGCTTTGTTTTACTATT
CTAATTGTGCAGACTCATACCGTGTTTCTACGAATATAAGACCCGGTCTT
ATATTAATTTCATAGCCAAAAAACGAACTAGGTTTCATTTTCGTGAGGAA
AACCAAAAGTACAAAACACGTTATTTTATAAAAACTCAACATTTTTACAA
TCAAAATTGTTTATTTGTTAAGCAAGAGCAACATACATTAACAAAACAAA
ACATTTAAAAAATAGAAACATGAAAAATTTATTCTAACACCATCATTTCA
TCCTATTCTGGAATGTCGTCATAACACATCAAACCTCGAATATTAATTTT
AATATTAATGTAAAAATGATTAATTTAATAACAGAGATATATTCTTTTTT
CAATATCGATGTAATTATTAAAAAAAAATTGGGGGAGAATTTTTAAAGGG
CCTTATGAAGTATAATAAAAAAAATTACGCCAAATCAACTGGATTTTGAA
AATGAATAATGTTTTATAATCAGCAATTTGTTATTGACAGTCAACAAATA
TTTCCCTCCGTTCACTGTGACAGAAGGCATTGAAAACAAACTATTAATAG
TCTAGCAAACTATTATGTGTCATACAAAAATTAATTTGTCGCGGTTCATT
AAAAATCGCAATAATAATTGCATAACAATTAACGCTAATTATTATTCTGC
GGACGCATCACGATTGCATTAGCATAATTCTGTGAGTTCCCTAATTGATC
CTGAAAATAAACCAATCGATAGTACAGAATAATGCTTAAAATTAAATTAT
GAAAGGGGGAATAATAAATAATTTTTATCCATTAAAACATGACATCATCA
CAAACCAAATACGTAACTAAGGCTTATAATAAGGAAGGGGCGCAAAATTT
GATAATTATGTAAACAGTTTGGATTGGAGACGTGGGTATTTTAATTTTGG
AACTGAGATGGATAAATAATTATGTAACTAATACTAAGGCTGCTGAATCT
CGCTACACAATAGACATTATAATAACGTATACTCATTGGTTTCTATATCA
ACTAAATATATAGAGCAGCGTTTCTCAAACTTTTCATATTGTGACATATA
AGATATAAGTAAAAAAATGCGGCCCATAATACATAAATTTATTAAAAAGA
C
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protein sequence of SMED30028687-orf-1

>SMED30028687-orf-1 ID=SMED30028687-orf-1|Name=SMED30028687-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=123bp
MKNIFEFKIQCEVFTIIGHSKLIFQLQVEDVEKTDIDQFDKDKSKNAINL
PGKRLFMDVIIYSPKEERGLGITKTILEQAAQSINRIMQLINNSHASIVK
IIIDIAKISTKHSITNLKKELK*
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protein sequence of SMED30028687-orf-2

>SMED30028687-orf-2 ID=SMED30028687-orf-2|Name=SMED30028687-orf-2|organism=Schmidtea mediterranea sexual|type=polypeptide|length=273bp
MDNIEVLKKLGIGAFAKVKLCKNKLSGRVFALKMPKNKNINAILNEISIF
STLKSSPSMILFHGIYLHSNKLCIAMEYISGKTLESVLKDENSLDYSLKL
QFVFQILQQIKSLHDAGIIHRDISCNNIMIYKENQNAKLIDFGLSISVKG
LNTDAIELSGKYGTPWYMAPELLTHEPYSNKIDIWSVGVVAVKIFSGERP
YTYLNPTKFQAKIAKDKTIELDPQNFSKDVFDFLSPCFKSDPKERPTVDD
LLSSKMFQINRSWQISRISRTD*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000034epidermis
PLANA:0002032epidermal cell
Vocabulary: INTERPRO
TermDefinition
IPR029071Ubiquitin-like_domsf
IPR000477RT_dom
IPR000719Prot_kinase_dom
IPR017441Protein_kinase_ATP_BS
IPR008266Tyr_kinase_AS
IPR011009Kinase-like_dom_sf
Vocabulary: molecular function
TermDefinition
GO:0004672protein kinase activity
GO:0005524ATP binding
Vocabulary: biological process
TermDefinition
GO:0006468protein phosphorylation