early growth response-4

Overview


Name	early growth response-4 (AFJ24726.1)
Smed ID	SMED30028658
Length (bp)	2783

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of early growth response-4 (SMED30028658) t-SNE clustered cells

Violin plots show distribution of expression levels for early growth response-4 (SMED30028658) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of early growth response-4 (SMED30028658) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for early growth response-4 (SMED30028658) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30028658

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 5

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication
nervous system	SMED30028658	SMESG000028801.1 SMESG000028800.1	dd_Smed_v4_9410_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
cephalic ganglia	SMED30028658	SMESG000028801.1 SMESG000028800.1	dd_Smed_v4_9410_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
muscle cell	SMED30028658	SMESG000028801.1 SMESG000028800.1	dd_Smed_v4_9410_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
cilated neuron	SMED30028658	SMESG000028801.1 SMESG000028800.1	dd_Smed_v4_9410_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
head region	SMED30028658	SMESG000028801.1 SMESG000028800.1	OX_Smed_1.0.17498	ox_Smed_v2	PMID:24238224 Kao et al., 2013

Note: Hover over icons to view figure legend

Homology

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BLAST of early growth response-4 vs. Ensembl Human
Match: EGR1 (early growth response 1 [Source:HGNC Symbol;Acc:HGNC:3238])

HSP 1 Score: 122.479 bits (306), Expect = 2.361e-28
Identity = 56/96 (58.33%), Postives = 71/96 (73.96%), Query Frame = -3

Query: 1654 RKPNIERNF--PCEFCPAKFSRRDELKRHEKIHSGEKPLSCPYCDKCFMRSDHRTTHIRTHTGEKPYSCDICSKRFARSDEKLRHKRIHLKEKSKK 1935
            + P  ER +  P E C  +FSR DEL RH +IH+G+KP  C  C + F RSDH TTHIRTHTGEKP++CDIC ++FARSDE+ RH +IHL++K KK
Sbjct:  330 KTPPHERPYACPVESCDRRFSRSDELTRHIRIHTGQKPFQCRICMRNFSRSDHLTTHIRTHTGEKPFACDICGRKFARSDERKRHTKIHLRQKDKK 425

[Close]

BLAST of early growth response-4 vs. Ensembl Human
Match: EGR3 (early growth response 3 [Source:HGNC Symbol;Acc:HGNC:3240])

HSP 1 Score: 119.783 bits (299), Expect = 2.553e-28
Identity = 66/148 (44.59%), Postives = 83/148 (56.08%), Query Frame = -3

Query: 1654 KDIHPNINSVSAIQLS-SPIEESSIYNRRSQRPPTDNKTLRKQAHEEKAHKIIIRKPNIERNFPCEFCPAKFSRRDELKRHEKIHSGEKPLSCPYCDKCFMRSDHRTTHIRTHTGEKPYSCDICSKRFARSDEKLRHKRIHLKEKSKK 2094
            K IHP   S+    L+  PI      NR S+ P      L ++ H                  P E C  +FSR DEL RH +IH+G KP  C  C + F RSDH TTHIRTHTGEKP++C+ C ++FARSDE+ RH +IHLK+K KK
Sbjct:  237 KQIHPGFGSLPQPPLTLKPIRPRKYPNRPSKTP------LHERPHA----------------CPAEGCDRRFSRSDELTRHLRIHTGHKPFQCRICMRSFSRSDHLTTHIRTHTGEKPFACEFCGRKFARSDERKRHAKIHLKQKEKK 362

[Close]

BLAST of early growth response-4 vs. Ensembl Human
Match: EGR3 (early growth response 3 [Source:HGNC Symbol;Acc:HGNC:3240])

HSP 1 Score: 118.627 bits (296), Expect = 2.793e-28
Identity = 66/148 (44.59%), Postives = 83/148 (56.08%), Query Frame = -3

Query: 1654 KDIHPNINSVSAIQLS-SPIEESSIYNRRSQRPPTDNKTLRKQAHEEKAHKIIIRKPNIERNFPCEFCPAKFSRRDELKRHEKIHSGEKPLSCPYCDKCFMRSDHRTTHIRTHTGEKPYSCDICSKRFARSDEKLRHKRIHLKEKSKK 2094
            K IHP   S+    L+  PI      NR S+ P      L ++ H                  P E C  +FSR DEL RH +IH+G KP  C  C + F RSDH TTHIRTHTGEKP++C+ C ++FARSDE+ RH +IHLK+K KK
Sbjct:  199 KQIHPGFGSLPQPPLTLKPIRPRKYPNRPSKTP------LHERPHA----------------CPAEGCDRRFSRSDELTRHLRIHTGHKPFQCRICMRSFSRSDHLTTHIRTHTGEKPFACEFCGRKFARSDERKRHAKIHLKQKEKK 324

[Close]

BLAST of early growth response-4 vs. Ensembl Human
Match: EGR2 (early growth response 2 [Source:HGNC Symbol;Acc:HGNC:3239])

HSP 1 Score: 119.398 bits (298), Expect = 5.556e-28
Identity = 60/137 (43.80%), Postives = 82/137 (59.85%), Query Frame = -3

Query: 1576 LRKQAHEEKAHKIIIRKPNIERNFPC--EFCPAKFSRRDELKRHEKIHSGEKPLSCPYCDKCFMRSDHRTTHIRTHTGEKPYSCDICSKRFARSDEKLRHKRIHLKEKSKKNITHEICLKLMSQANMENSNKIESKL 1980
            LR + +  +  K  +     ER +PC  E C  +FSR DEL RH +IH+G KP  C  C + F RSDH TTHIRTHTGEKP++CD C ++FARSDE+ RH +IHL++K +K+      +   S A+     +    L
Sbjct:  271 LRPRKYPNRPSKTPVH----ERPYPCPAEGCDRRFSRSDELTRHIRIHTGHKPFQCRICMRNFSRSDHLTTHIRTHTGEKPFACDYCGRKFARSDERKRHTKIHLRQKERKSSAPSASVPAPSTASCSGGVQPGGTL 403

[Close]

BLAST of early growth response-4 vs. Ensembl Human
Match: EGR2 (early growth response 2 [Source:HGNC Symbol;Acc:HGNC:3239])

HSP 1 Score: 120.168 bits (300), Expect = 6.533e-28
Identity = 60/137 (43.80%), Postives = 82/137 (59.85%), Query Frame = -3

Query: 1576 LRKQAHEEKAHKIIIRKPNIERNFPC--EFCPAKFSRRDELKRHEKIHSGEKPLSCPYCDKCFMRSDHRTTHIRTHTGEKPYSCDICSKRFARSDEKLRHKRIHLKEKSKKNITHEICLKLMSQANMENSNKIESKL 1980
            LR + +  +  K  +     ER +PC  E C  +FSR DEL RH +IH+G KP  C  C + F RSDH TTHIRTHTGEKP++CD C ++FARSDE+ RH +IHL++K +K+      +   S A+     +    L
Sbjct:  321 LRPRKYPNRPSKTPVH----ERPYPCPAEGCDRRFSRSDELTRHIRIHTGHKPFQCRICMRNFSRSDHLTTHIRTHTGEKPFACDYCGRKFARSDERKRHTKIHLRQKERKSSAPSASVPAPSTASCSGGVQPGGTL 453

[Close]

BLAST of early growth response-4 vs. Ensembl Celegans
Match: egrh-2 (EGR (Early Growth factor Response factor) Homolog [Source:UniProtKB/TrEMBL;Acc:U4PM44])

HSP 1 Score: 107.457 bits (267), Expect = 2.759e-27
Identity = 51/82 (62.20%), Postives = 61/82 (74.39%), Query Frame = -3

Query: 1663 PCEFCPAKFSRRDELKRHEKIHSGEKPLSCPYCDKCFMRSDHRTTHIRTHTGEKPYSCDICSKRFARSDEKLRHKRIHLKEK 1908
            P + C  KFSR DEL RH +IH+G+KP  C  C + F RSDH TTH+RTHTGEKPYSCDIC K+FAR DE+ RH +IH K +
Sbjct:   16 PRDECDKKFSRSDELTRHIRIHTGQKPFQCRICMRRFSRSDHLTTHVRTHTGEKPYSCDICGKKFARCDERTRHTKIHKKSQ 97

HSP 2 Score: 53.9138 bits (128), Expect = 1.663e-8
Identity = 27/60 (45.00%), Postives = 33/60 (55.00%), Query Frame = -3

Query: 1759 IRKPNIERNFPCEFCPAKFSRRDELKRHEKIHSGEKPLSCPYCDKCFMRSDHRTTHIRTH 1938
            IR    ++ F C  C  +FSR D L  H + H+GEKP SC  C K F R D RT H + H
Sbjct:   34 IRIHTGQKPFQCRICMRRFSRSDHLTTHVRTHTGEKPYSCDICGKKFARCDERTRHTKIH 93

[Close]

BLAST of early growth response-4 vs. Ensembl Celegans
Match: egrh-2 (EGR (Early Growth factor Response factor) Homolog [Source:UniProtKB/TrEMBL;Acc:U4PM44])

HSP 1 Score: 112.079 bits (279), Expect = 5.551e-27
Identity = 51/82 (62.20%), Postives = 61/82 (74.39%), Query Frame = -3

Query: 1663 PCEFCPAKFSRRDELKRHEKIHSGEKPLSCPYCDKCFMRSDHRTTHIRTHTGEKPYSCDICSKRFARSDEKLRHKRIHLKEK 1908
            P + C  KFSR DEL RH +IH+G+KP  C  C + F RSDH TTH+RTHTGEKPYSCDIC K+FAR DE+ RH +IH K +
Sbjct:  181 PRDECDKKFSRSDELTRHIRIHTGQKPFQCRICMRRFSRSDHLTTHVRTHTGEKPYSCDICGKKFARCDERTRHTKIHKKSQ 262

HSP 2 Score: 56.225 bits (134), Expect = 3.386e-8
Identity = 27/60 (45.00%), Postives = 33/60 (55.00%), Query Frame = -3

Query: 1759 IRKPNIERNFPCEFCPAKFSRRDELKRHEKIHSGEKPLSCPYCDKCFMRSDHRTTHIRTH 1938
            IR    ++ F C  C  +FSR D L  H + H+GEKP SC  C K F R D RT H + H
Sbjct:  199 IRIHTGQKPFQCRICMRRFSRSDHLTTHVRTHTGEKPYSCDICGKKFARCDERTRHTKIH 258

[Close]

BLAST of early growth response-4 vs. Ensembl Celegans
Match: egrh-2 (EGR (Early Growth factor Response factor) Homolog [Source:UniProtKB/TrEMBL;Acc:U4PM44])

HSP 1 Score: 106.686 bits (265), Expect = 7.462e-27
Identity = 51/82 (62.20%), Postives = 60/82 (73.17%), Query Frame = -3

Query: 1651 CPAKFSRRDELKRHEKIHSGEKPLSCPYCDKCFMRSDHRTTHIRTHTGEKPYSCDICSKRFARSDEKLRHKRIHLKEKSKKN 1896
            C  KFSR DEL RH +IH+G+KP  C  C + F RSDH TTH+RTHTGEKPYSCDIC K+FAR DE+ RH +IH K    K+
Sbjct:   20 CDKKFSRSDELTRHIRIHTGQKPFQCRICMRRFSRSDHLTTHVRTHTGEKPYSCDICGKKFARCDERTRHTKIHKKSGPGKH 101

HSP 2 Score: 54.6842 bits (130), Expect = 1.340e-8
Identity = 28/65 (43.08%), Postives = 34/65 (52.31%), Query Frame = -3

Query: 1744 IRKPNIERNFPCEFCPAKFSRRDELKRHEKIHSGEKPLSCPYCDKCFMRSDHRTTHIRTHTGEKP 1938
            IR    ++ F C  C  +FSR D L  H + H+GEKP SC  C K F R D RT H + H    P
Sbjct:   34 IRIHTGQKPFQCRICMRRFSRSDHLTTHVRTHTGEKPYSCDICGKKFARCDERTRHTKIHKKSGP 98

[Close]

BLAST of early growth response-4 vs. Ensembl Celegans
Match: egrh-2 (EGR (Early Growth factor Response factor) Homolog [Source:UniProtKB/TrEMBL;Acc:U4PM44])

HSP 1 Score: 111.309 bits (277), Expect = 1.402e-26
Identity = 52/85 (61.18%), Postives = 61/85 (71.76%), Query Frame = -3

Query: 1654 PCEFCPAKFSRRDELKRHEKIHSGEKPLSCPYCDKCFMRSDHRTTHIRTHTGEKPYSCDICSKRFARSDEKLRHKRIHLKEKSKK 1908
            P + C  KFSR DEL RH +IH+G+KP  C  C + F RSDH TTH+RTHTGEKPYSCDIC K+FAR DE+ RH +IH K    K
Sbjct:  181 PRDECDKKFSRSDELTRHIRIHTGQKPFQCRICMRRFSRSDHLTTHVRTHTGEKPYSCDICGKKFARCDERTRHTKIHKKSGPGK 265

HSP 2 Score: 56.6102 bits (135), Expect = 2.793e-8
Identity = 28/65 (43.08%), Postives = 34/65 (52.31%), Query Frame = -3

Query: 1744 IRKPNIERNFPCEFCPAKFSRRDELKRHEKIHSGEKPLSCPYCDKCFMRSDHRTTHIRTHTGEKP 1938
            IR    ++ F C  C  +FSR D L  H + H+GEKP SC  C K F R D RT H + H    P
Sbjct:  199 IRIHTGQKPFQCRICMRRFSRSDHLTTHVRTHTGEKPYSCDICGKKFARCDERTRHTKIHKKSGP 263

[Close]

BLAST of early growth response-4 vs. Ensembl Celegans
Match: egrh-1 (EGR (Early Growth factor Response factor) Homolog [Source:UniProtKB/TrEMBL;Acc:Q18250])

HSP 1 Score: 111.309 bits (277), Expect = 1.601e-25
Identity = 48/83 (57.83%), Postives = 62/83 (74.70%), Query Frame = -3

Query: 1660 PCEFCPAKFSRRDELKRHEKIHSGEKPLSCPYCDKCFMRSDHRTTHIRTHTGEKPYSCDICSKRFARSDEKLRHKRIHLKEKS 1908
            P + C  +FSR DEL RH +IH+G+KP  C  C + F RSDH TTH+RTHTGEKP+SCDIC ++FARSDE+ RH ++H   +S
Sbjct:  377 PRDGCDRRFSRSDELTRHIRIHTGQKPFQCRICMRAFSRSDHLTTHVRTHTGEKPFSCDICGRKFARSDERKRHTKVHKTSRS 459

[Close]

BLAST of early growth response-4 vs. Ensembl Fly
Match: sr (gene:FBgn0003499 transcript:FBtr0330050)

HSP 1 Score: 125.176 bits (313), Expect = 9.325e-29
Identity = 57/96 (59.38%), Postives = 71/96 (73.96%), Query Frame = -3

Query: 1654 RKPNIERNF--PCEFCPAKFSRRDELKRHEKIHSGEKPLSCPYCDKCFMRSDHRTTHIRTHTGEKPYSCDICSKRFARSDEKLRHKRIHLKEKSKK 1935
            + P  ER +  P E C  +FSR DEL RH +IH+G+KP  C  C + F RSDH TTHIRTHTGEKP+SCDIC ++FARSDEK RH ++HLK++ KK
Sbjct: 1028 KTPVHERPYACPVENCDRRFSRSDELTRHIRIHTGQKPFQCRICMRSFSRSDHLTTHIRTHTGEKPFSCDICGRKFARSDEKKRHAKVHLKQRIKK 1123

[Close]

BLAST of early growth response-4 vs. Ensembl Fly
Match: sr (gene:FBgn0003499 transcript:FBtr0083542)

HSP 1 Score: 125.176 bits (313), Expect = 9.802e-29
Identity = 57/96 (59.38%), Postives = 71/96 (73.96%), Query Frame = -3

Query: 1654 RKPNIERNF--PCEFCPAKFSRRDELKRHEKIHSGEKPLSCPYCDKCFMRSDHRTTHIRTHTGEKPYSCDICSKRFARSDEKLRHKRIHLKEKSKK 1935
            + P  ER +  P E C  +FSR DEL RH +IH+G+KP  C  C + F RSDH TTHIRTHTGEKP+SCDIC ++FARSDEK RH ++HLK++ KK
Sbjct: 1028 KTPVHERPYACPVENCDRRFSRSDELTRHIRIHTGQKPFQCRICMRSFSRSDHLTTHIRTHTGEKPFSCDICGRKFARSDEKKRHAKVHLKQRIKK 1123

[Close]

BLAST of early growth response-4 vs. Ensembl Fly
Match: sr (gene:FBgn0003499 transcript:FBtr0301615)

HSP 1 Score: 123.635 bits (309), Expect = 1.190e-28
Identity = 57/96 (59.38%), Postives = 71/96 (73.96%), Query Frame = -3

Query: 1654 RKPNIERNF--PCEFCPAKFSRRDELKRHEKIHSGEKPLSCPYCDKCFMRSDHRTTHIRTHTGEKPYSCDICSKRFARSDEKLRHKRIHLKEKSKK 1935
            + P  ER +  P E C  +FSR DEL RH +IH+G+KP  C  C + F RSDH TTHIRTHTGEKP+SCDIC ++FARSDEK RH ++HLK++ KK
Sbjct:  559 KTPVHERPYACPVENCDRRFSRSDELTRHIRIHTGQKPFQCRICMRSFSRSDHLTTHIRTHTGEKPFSCDICGRKFARSDEKKRHAKVHLKQRIKK 654

[Close]

BLAST of early growth response-4 vs. Ensembl Fly
Match: sr (gene:FBgn0003499 transcript:FBtr0344633)

HSP 1 Score: 123.635 bits (309), Expect = 2.123e-28
Identity = 57/96 (59.38%), Postives = 71/96 (73.96%), Query Frame = -3

Query: 1654 RKPNIERNFPC--EFCPAKFSRRDELKRHEKIHSGEKPLSCPYCDKCFMRSDHRTTHIRTHTGEKPYSCDICSKRFARSDEKLRHKRIHLKEKSKK 1935
            + P  ER + C  E C  +FSR DEL RH +IH+G+KP  C  C + F RSDH TTHIRTHTGEKP+SCDIC ++FARSDEK RH ++HLK++ KK
Sbjct:  748 KTPVHERPYACPVENCDRRFSRSDELTRHIRIHTGQKPFQCRICMRSFSRSDHLTTHIRTHTGEKPFSCDICGRKFARSDEKKRHAKVHLKQRIKK 843

[Close]

BLAST of early growth response-4 vs. Ensembl Fly
Match: sr (gene:FBgn0003499 transcript:FBtr0083543)

HSP 1 Score: 123.635 bits (309), Expect = 2.123e-28
Identity = 57/96 (59.38%), Postives = 71/96 (73.96%), Query Frame = -3

Query: 1654 RKPNIERNFPC--EFCPAKFSRRDELKRHEKIHSGEKPLSCPYCDKCFMRSDHRTTHIRTHTGEKPYSCDICSKRFARSDEKLRHKRIHLKEKSKK 1935
            + P  ER + C  E C  +FSR DEL RH +IH+G+KP  C  C + F RSDH TTHIRTHTGEKP+SCDIC ++FARSDEK RH ++HLK++ KK
Sbjct:  748 KTPVHERPYACPVENCDRRFSRSDELTRHIRIHTGQKPFQCRICMRSFSRSDHLTTHIRTHTGEKPFSCDICGRKFARSDEKKRHAKVHLKQRIKK 843

[Close]

BLAST of early growth response-4 vs. Ensembl Zebrafish
Match: egr2a (early growth response 2a [Source:ZFIN;Acc:ZDB-GENE-030723-6])

HSP 1 Score: 120.939 bits (302), Expect = 3.542e-30
Identity = 67/148 (45.27%), Postives = 86/148 (58.11%), Query Frame = -3

Query: 1654 INSVSAIQLSSPIEESSIYNRRSQRPPTD-----NKTLRKQAHEEKAHKIIIRKPNIERNFPC--EFCPAKFSRRDELKRHEKIHSGEKPLSCPYCDKCFMRSDHRTTHIRTHTGEKPYSCDICSKRFARSDEKLRHKRIHLKEKSKK 2076
            +N++    L+ P++ S        RPP D     N  LR      K      + P  ER +PC  E C  +FSR DEL RH +IH+G KP  C  C + F RSDH TTHIRTHTGEKP+SCD C ++FARSDE+ RH +IH + K +K
Sbjct:   96 LNTIRNFTLACPVDGS--------RPPLDGTNPQNVPLRPILRPRKYPNRPCKTPVHERPYPCPAEGCDRRFSRSDELTRHVRIHTGHKPFQCRICMRSFSRSDHLTTHIRTHTGEKPFSCDFCGRKFARSDERRRHTKIHQRHKDRK 235

[Close]

Query: 1654 INSVSAIQLSSPIEESSIYNRRSQRPPTD-----NKTLRKQAHEEKAHKIIIRKPNIERNFPC--EFCPAKFSRRDELKRHEKIHSGEKPLSCPYCDKCFMRSDHRTTHIRTHTGEKPYSCDICSKRFARSDEKLRHKRIHLKEKSKK 2076
            +N++    L+ P++ S        RPP D     N  LR      K      + P  ER +PC  E C  +FSR DEL RH +IH+G KP  C  C + F RSDH TTHIRTHTGEKP+SCD C ++FARSDE+ RH +IH + K +K
Sbjct:   96 LNTIRNFTLACPVDGS--------RPPLDGTNPQNVPLRPILRPRKYPNRPCKTPVHERPYPCPAEGCDRRFSRSDELTRHVRIHTGHKPFQCRICMRSFSRSDHLTTHIRTHTGEKPFSCDFCGRKFARSDERRRHTKIHQRHKDRK 235

[Close]

BLAST of early growth response-4 vs. Ensembl Zebrafish
Match: egr4 (early growth response 4 [Source:ZFIN;Acc:ZDB-GENE-080204-90])

HSP 1 Score: 122.479 bits (306), Expect = 1.172e-29
Identity = 70/161 (43.48%), Postives = 89/161 (55.28%), Query Frame = -3

Query: 1636 SLYISINYKDIHPNINSVSAIQLSSPIEESSIYNRRSQRPPTDNKTLRKQAHEEKAHKIIIRKPNIERNFPCEFCPAKFSRRDELKRHEKIHSGEKPLSCPYCDKCFMRSDHRTTHIRTHTGEKPYSCDICSKRFARSDEKLRHKRIHLKEKSKKNITHEI 2118
            SLYIS       PN     A  L+  ++     N  +QR        RK A  EK               P E C  +FSR DEL RH +IH+G KP  C  C +CF RSDH TTH+RTHTGEKP+SCD+C++RFARSDE+ RH R+HLK++ +     E+
Sbjct:  208 SLYISF------PN-----AFGLADALDSLLATNTHAQR---SKPRARKGAAREKPFSC-----------PVESCERRFSRSDELNRHVRIHTGHKPFQCRVCLRCFSRSDHLTTHMRTHTGEKPFSCDVCARRFARSDERKRHMRVHLKQRERMQQKTEL 343

[Close]

BLAST of early growth response-4 vs. Ensembl Zebrafish
Match: egr2a (early growth response 2a [Source:ZFIN;Acc:ZDB-GENE-030723-6])

HSP 1 Score: 122.479 bits (306), Expect = 2.219e-29
Identity = 67/148 (45.27%), Postives = 86/148 (58.11%), Query Frame = -3

Query: 1654 INSVSAIQLSSPIEESSIYNRRSQRPPTD-----NKTLRKQAHEEKAHKIIIRKPNIERNFPC--EFCPAKFSRRDELKRHEKIHSGEKPLSCPYCDKCFMRSDHRTTHIRTHTGEKPYSCDICSKRFARSDEKLRHKRIHLKEKSKK 2076
            +N++    L+ P++ S        RPP D     N  LR      K      + P  ER +PC  E C  +FSR DEL RH +IH+G KP  C  C + F RSDH TTHIRTHTGEKP+SCD C ++FARSDE+ RH +IH + K +K
Sbjct:  241 LNTIRNFTLACPVDGS--------RPPLDGTNPQNVPLRPILRPRKYPNRPCKTPVHERPYPCPAEGCDRRFSRSDELTRHVRIHTGHKPFQCRICMRSFSRSDHLTTHIRTHTGEKPFSCDFCGRKFARSDERRRHTKIHQRHKDRK 380

[Close]

BLAST of early growth response-4 vs. Ensembl Zebrafish
Match: egr2b (early growth response 2b [Source:NCBI gene;Acc:30190])

HSP 1 Score: 119.783 bits (299), Expect = 2.575e-28
Identity = 65/147 (44.22%), Postives = 85/147 (57.82%), Query Frame = -3

Query: 1654 INSVSAIQLSSPIEESSIYNRRSQRPPT----DNKTLRKQAHEEKAHKIIIRKPNIERNFPC--EFCPAKFSRRDELKRHEKIHSGEKPLSCPYCDKCFMRSDHRTTHIRTHTGEKPYSCDICSKRFARSDEKLRHKRIHLKEKSKK 2076
            +N++    L  P+ +         R PT     N  LR      K      + P  ER +PC  E C  +FSR DEL RH +IH+G KP  C  C + F RSDH TTHIRTHTGEKP++CD C ++FARSDE+ RH +IHL++K +K
Sbjct:  247 LNTIRNFTLGGPVPDGP-------RLPTAYTPQNLPLRPILRPRKYPNRPSKTPVHERPYPCPAEGCDRRFSRSDELTRHIRIHTGHKPFQCRICMRNFSRSDHLTTHIRTHTGEKPFACDFCGRKFARSDERKRHTKIHLRQKERK 386

[Close]

BLAST of early growth response-4 vs. Ensembl Xenopus
Match: egr1 (early growth response 1 [Source:NCBI gene;Acc:100038164])

HSP 1 Score: 122.865 bits (307), Expect = 7.784e-29
Identity = 56/96 (58.33%), Postives = 71/96 (73.96%), Query Frame = -3

Query: 1654 RKPNIERNF--PCEFCPAKFSRRDELKRHEKIHSGEKPLSCPYCDKCFMRSDHRTTHIRTHTGEKPYSCDICSKRFARSDEKLRHKRIHLKEKSKK 1935
            + P  ER +  P E C  +FSR DEL RH +IH+G+KP  C  C + F RSDH TTHIRTHTGEKP++CDIC ++FARSDE+ RH +IHL++K KK
Sbjct:  272 KTPPHERPYACPVESCDRRFSRSDELTRHIRIHTGQKPFQCRICMRNFSRSDHLTTHIRTHTGEKPFACDICGRKFARSDERKRHTKIHLRQKDKK 367

[Close]

BLAST of early growth response-4 vs. Ensembl Xenopus
Match: egr1 (early growth response 1 [Source:NCBI gene;Acc:100038164])

HSP 1 Score: 122.865 bits (307), Expect = 8.748e-29
Identity = 56/96 (58.33%), Postives = 71/96 (73.96%), Query Frame = -3

Query: 1654 RKPNIERNF--PCEFCPAKFSRRDELKRHEKIHSGEKPLSCPYCDKCFMRSDHRTTHIRTHTGEKPYSCDICSKRFARSDEKLRHKRIHLKEKSKK 1935
            + P  ER +  P E C  +FSR DEL RH +IH+G+KP  C  C + F RSDH TTHIRTHTGEKP++CDIC ++FARSDE+ RH +IHL++K KK
Sbjct:  299 KTPPHERPYACPVESCDRRFSRSDELTRHIRIHTGQKPFQCRICMRNFSRSDHLTTHIRTHTGEKPFACDICGRKFARSDERKRHTKIHLRQKDKK 394

[Close]

BLAST of early growth response-4 vs. Ensembl Xenopus
Match: tbl1x (transducin beta like 1 X-linked [Source:Xenbase;Acc:XB-GENE-982285])

HSP 1 Score: 120.168 bits (300), Expect = 1.999e-28
Identity = 60/115 (52.17%), Postives = 75/115 (65.22%), Query Frame = -3

Query: 1651 NKTLRKQAHEEKAHKIIIRKPNIERNFPC--EFCPAKFSRRDELKRHEKIHSGEKPLSCPYCDKCFMRSDHRTTHIRTHTGEKPYSCDICSKRFARSDEKLRHKRIHLKEKSKKN 1989
            N  LR      K      + P  ER +PC  E C  +FSR DEL RH +IH+G KP  C  C + F RSDH TTHIRTHTGEKP++CD C ++FARSDE+ RH +IHL++K +KN
Sbjct:  235 NLPLRPILRPRKYPNRPSKTPVHERPYPCPAEGCDRRFSRSDELTRHIRIHTGHKPFQCRICMRNFSRSDHLTTHIRTHTGEKPFACDYCGRKFARSDERKRHTKIHLRQKERKN 349

[Close]

BLAST of early growth response-4 vs. Ensembl Xenopus
Match: serpinb4 (serpin peptidase inhibitor, clade B (ovalbumin), member 4 [Source:Xenbase;Acc:XB-GENE-5787878])

HSP 1 Score: 115.931 bits (289), Expect = 3.416e-27
Identity = 60/131 (45.80%), Postives = 81/131 (61.83%), Query Frame = -3

Query: 1633 YNRRSQRPPTDNKTLRKQAHEEKAHKIII-RKPNIERNFPCEFCPAKFSRRDELKRHEKIHSGEKPLSCPYCDKCFMRSDHRTTHIRTHTGEKPYSCDICSKRFARSDEKLRHKRIHLKEKSKKNITHEIC 2022
            +     +PP   K +R + +  +  K  +  +P+     P E C  +FSR DEL RH +IH+G KP  C  C + F RSDH TTHIRTHTGEKP++CD C ++FARSDE+ RH +IHLK+K KK     +C
Sbjct:  239 FGGMGHQPPLTLKPIRPRKYPNRPSKTPLHERPHA---CPAEGCDRRFSRSDELTRHLRIHTGHKPFQCRICMRSFSRSDHLTTHIRTHTGEKPFACDFCGRKFARSDERKRHAKIHLKQKDKKGGDKAVC 366

[Close]

BLAST of early growth response-4 vs. Ensembl Xenopus
Match: usp31 (ubiquitin specific peptidase 31 [Source:Xenbase;Acc:XB-GENE-920956])

HSP 1 Score: 115.931 bits (289), Expect = 2.924e-26
Identity = 51/84 (60.71%), Postives = 64/84 (76.19%), Query Frame = -3

Query: 1657 PCEFCPAKFSRRDELKRHEKIHSGEKPLSCPYCDKCFMRSDHRTTHIRTHTGEKPYSCDICSKRFARSDEKLRHKRIHLKEKSK 1908
            P E C   F+R DEL RH +IH+G KP  C  C + F RSDH TTHIRTHTGEKP+SCD+C +RFARSDEK RH ++H+K+K++
Sbjct:  443 PVESCIRSFARSDELNRHLRIHTGHKPFQCRICLRNFSRSDHLTTHIRTHTGEKPFSCDLCGRRFARSDEKKRHGKVHMKQKAR 526

[Close]

BLAST of early growth response-4 vs. Ensembl Mouse
Match: Egr1 (early growth response 1 [Source:MGI Symbol;Acc:MGI:95295])

HSP 1 Score: 122.479 bits (306), Expect = 1.562e-28
Identity = 56/96 (58.33%), Postives = 71/96 (73.96%), Query Frame = -3

Query: 1654 RKPNIERNF--PCEFCPAKFSRRDELKRHEKIHSGEKPLSCPYCDKCFMRSDHRTTHIRTHTGEKPYSCDICSKRFARSDEKLRHKRIHLKEKSKK 1935
            + P  ER +  P E C  +FSR DEL RH +IH+G+KP  C  C + F RSDH TTHIRTHTGEKP++CDIC ++FARSDE+ RH +IHL++K KK
Sbjct:  328 KTPPHERPYACPVESCDRRFSRSDELTRHIRIHTGQKPFQCRICMRNFSRSDHLTTHIRTHTGEKPFACDICGRKFARSDERKRHTKIHLRQKDKK 423

[Close]

Query: 1654 RKPNIERNF--PCEFCPAKFSRRDELKRHEKIHSGEKPLSCPYCDKCFMRSDHRTTHIRTHTGEKPYSCDICSKRFARSDEKLRHKRIHLKEKSKK 1935
            + P  ER +  P E C  +FSR DEL RH +IH+G+KP  C  C + F RSDH TTHIRTHTGEKP++CDIC ++FARSDE+ RH +IHL++K KK
Sbjct:  328 KTPPHERPYACPVESCDRRFSRSDELTRHIRIHTGQKPFQCRICMRNFSRSDHLTTHIRTHTGEKPFACDICGRKFARSDERKRHTKIHLRQKDKK 423

[Close]

BLAST of early growth response-4 vs. Ensembl Mouse
Match: Egr3 (early growth response 3 [Source:MGI Symbol;Acc:MGI:1306780])

HSP 1 Score: 119.013 bits (297), Expect = 1.604e-28
Identity = 66/149 (44.30%), Postives = 84/149 (56.38%), Query Frame = -3

Query: 1651 KDIHPNINSVSAIQLS-SPIEESSIYNRRSQRPPTDNKTLRKQAHEEKAHKIIIRKPNIERNFPCEFCPAKFSRRDELKRHEKIHSGEKPLSCPYCDKCFMRSDHRTTHIRTHTGEKPYSCDICSKRFARSDEKLRHKRIHLKEKSKKN 2094
            K IHP   S+    L+  PI      NR S+ P      L ++ H                  P E C  +FSR DEL RH +IH+G KP  C  C + F RSDH TTHIRTHTGEKP++C+ C ++FARSDE+ RH +IHLK+K KK+
Sbjct:  199 KQIHPGFGSLPQPPLTLKPIRPRKYPNRPSKTP------LHERPHA----------------CPAEGCDRRFSRSDELTRHLRIHTGHKPFQCRICMRSFSRSDHLTTHIRTHTGEKPFACEFCGRKFARSDERKRHAKIHLKQKEKKS 325

[Close]

BLAST of early growth response-4 vs. Ensembl Mouse
Match: Egr3 (early growth response 3 [Source:MGI Symbol;Acc:MGI:1306780])

HSP 1 Score: 119.783 bits (299), Expect = 1.657e-28
Identity = 66/149 (44.30%), Postives = 84/149 (56.38%), Query Frame = -3

Query: 1651 KDIHPNINSVSAIQLS-SPIEESSIYNRRSQRPPTDNKTLRKQAHEEKAHKIIIRKPNIERNFPCEFCPAKFSRRDELKRHEKIHSGEKPLSCPYCDKCFMRSDHRTTHIRTHTGEKPYSCDICSKRFARSDEKLRHKRIHLKEKSKKN 2094
            K IHP   S+    L+  PI      NR S+ P      L ++ H                  P E C  +FSR DEL RH +IH+G KP  C  C + F RSDH TTHIRTHTGEKP++C+ C ++FARSDE+ RH +IHLK+K KK+
Sbjct:  237 KQIHPGFGSLPQPPLTLKPIRPRKYPNRPSKTP------LHERPHA----------------CPAEGCDRRFSRSDELTRHLRIHTGHKPFQCRICMRSFSRSDHLTTHIRTHTGEKPFACEFCGRKFARSDERKRHAKIHLKQKEKKS 363

[Close]

BLAST of early growth response-4 vs. Ensembl Mouse
Match: Egr2 (early growth response 2 [Source:MGI Symbol;Acc:MGI:95296])

HSP 1 Score: 117.857 bits (294), Expect = 1.481e-27
Identity = 57/111 (51.35%), Postives = 75/111 (67.57%), Query Frame = -3

Query: 1654 LRKQAHEEKAHKIIIRKPNIERNFPC--EFCPAKFSRRDELKRHEKIHSGEKPLSCPYCDKCFMRSDHRTTHIRTHTGEKPYSCDICSKRFARSDEKLRHKRIHLKEKSKK 1980
            LR + +  +  K  +     ER +PC  E C  +FSR DEL RH +IH+G KP  C  C + F RSDH TTHIRTHTGEKP++CD C ++FARSDE+ RH +IHL++K +K
Sbjct:  268 LRPRKYPNRPSKTPVH----ERPYPCPAEGCDRRFSRSDELTRHIRIHTGHKPFQCRICMRNFSRSDHLTTHIRTHTGEKPFACDYCGRKFARSDERKRHTKIHLRQKERK 374

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BLAST of early growth response-4 vs. UniProt/SwissProt
Match: sp|O73693|EGR1_TAEGU (Early growth response protein 1 (Fragment) OS=Taeniopygia guttata OX=59729 GN=EGR1 PE=3 SV=1)

HSP 1 Score: 116.316 bits (290), Expect = 2.785e-28
Identity = 51/81 (62.96%), Postives = 64/81 (79.01%), Query Frame = -3

Query: 1654 CPAKFSRRDELKRHEKIHSGEKPLSCPYCDKCFMRSDHRTTHIRTHTGEKPYSCDICSKRFARSDEKLRHKRIHLKEKSKK 1896
            C  +FSR DEL RH +IH+G+KP  C  C + F RSDH TTHIRTHTGEKP++CDIC ++FARSDE+ RH +IHL++K KK
Sbjct:    1 CDRRFSRSDELTRHIRIHTGQKPFQCRICMRNFSRSDHLTTHIRTHTGEKPFACDICGRKFARSDERKRHTKIHLRQKDKK 81

HSP 2 Score: 53.1434 bits (126), Expect = 1.536e-6
Identity = 26/64 (40.62%), Postives = 34/64 (53.12%), Query Frame = -3

Query: 1747 IRKPNIERNFPCEFCPAKFSRRDELKRHEKIHSGEKPLSCPYCDKCFMRSDHRTTHIRTHTGEK 1938
            IR    ++ F C  C   FSR D L  H + H+GEKP +C  C + F RSD R  H + H  +K
Sbjct:   15 IRIHTGQKPFQCRICMRNFSRSDHLTTHIRTHTGEKPFACDICGRKFARSDERKRHTKIHLRQK 78

[Close]

BLAST of early growth response-4 vs. UniProt/SwissProt
Match: sp|O73692|EGR1_COTJA (Early growth response protein 1 (Fragment) OS=Coturnix japonica OX=93934 GN=EGR1 PE=3 SV=1)

HSP 1 Score: 116.316 bits (290), Expect = 2.918e-28
Identity = 51/81 (62.96%), Postives = 64/81 (79.01%), Query Frame = -3

Query: 1654 CPAKFSRRDELKRHEKIHSGEKPLSCPYCDKCFMRSDHRTTHIRTHTGEKPYSCDICSKRFARSDEKLRHKRIHLKEKSKK 1896
            C  +FSR DEL RH +IH+G+KP  C  C + F RSDH TTHIRTHTGEKP++CDIC ++FARSDE+ RH +IHL++K KK
Sbjct:    1 CDRRFSRSDELTRHIRIHTGQKPFQCRICMRNFSRSDHLTTHIRTHTGEKPFACDICGRKFARSDERKRHTKIHLRQKDKK 81

HSP 2 Score: 53.5286 bits (127), Expect = 1.380e-6
Identity = 26/64 (40.62%), Postives = 34/64 (53.12%), Query Frame = -3

Query: 1747 IRKPNIERNFPCEFCPAKFSRRDELKRHEKIHSGEKPLSCPYCDKCFMRSDHRTTHIRTHTGEK 1938
            IR    ++ F C  C   FSR D L  H + H+GEKP +C  C + F RSD R  H + H  +K
Sbjct:   15 IRIHTGQKPFQCRICMRNFSRSDHLTTHIRTHTGEKPFACDICGRKFARSDERKRHTKIHLRQK 78

[Close]

BLAST of early growth response-4 vs. UniProt/SwissProt
Match: sp|A4II20|EGR1_XENTR (Early growth response protein 1 OS=Xenopus tropicalis OX=8364 GN=egr1 PE=2 SV=2)

HSP 1 Score: 122.865 bits (307), Expect = 4.634e-28
Identity = 56/96 (58.33%), Postives = 71/96 (73.96%), Query Frame = -3

Query: 1654 RKPNIERNF--PCEFCPAKFSRRDELKRHEKIHSGEKPLSCPYCDKCFMRSDHRTTHIRTHTGEKPYSCDICSKRFARSDEKLRHKRIHLKEKSKK 1935
            + P  ER +  P E C  +FSR DEL RH +IH+G+KP  C  C + F RSDH TTHIRTHTGEKP++CDIC ++FARSDE+ RH +IHL++K KK
Sbjct:  299 KTPPHERPYACPVESCDRRFSRSDELTRHIRIHTGQKPFQCRICMRNFSRSDHLTTHIRTHTGEKPFACDICGRKFARSDERKRHTKIHLRQKDKK 394

[Close]

BLAST of early growth response-4 vs. UniProt/SwissProt
Match: sp|O73691|EGR1_CHICK (Early growth response protein 1 (Fragment) OS=Gallus gallus OX=9031 GN=EGR1 PE=3 SV=1)

HSP 1 Score: 115.546 bits (288), Expect = 4.635e-28
Identity = 51/81 (62.96%), Postives = 64/81 (79.01%), Query Frame = -3

Query: 1654 CPAKFSRRDELKRHEKIHSGEKPLSCPYCDKCFMRSDHRTTHIRTHTGEKPYSCDICSKRFARSDEKLRHKRIHLKEKSKK 1896
            C  +FSR DEL RH +IH+G+KP  C  C + F RSDH TTHIRTHTGEKP++CDIC ++FARSDE+ RH +IHL++K KK
Sbjct:    1 CDRRFSRSDELTRHIRIHTGQKPFQCRICMRNFSRSDHLTTHIRTHTGEKPFACDICGRKFARSDERKRHTKIHLRQKDKK 81

HSP 2 Score: 53.5286 bits (127), Expect = 1.210e-6
Identity = 26/64 (40.62%), Postives = 34/64 (53.12%), Query Frame = -3

Query: 1747 IRKPNIERNFPCEFCPAKFSRRDELKRHEKIHSGEKPLSCPYCDKCFMRSDHRTTHIRTHTGEK 1938
            IR    ++ F C  C   FSR D L  H + H+GEKP +C  C + F RSD R  H + H  +K
Sbjct:   15 IRIHTGQKPFQCRICMRNFSRSDHLTTHIRTHTGEKPFACDICGRKFARSDERKRHTKIHLRQK 78

[Close]

BLAST of early growth response-4 vs. UniProt/SwissProt
Match: sp|Q6GQH4|EGR1A_XENLA (Early growth response protein 1-A OS=Xenopus laevis OX=8355 GN=egr1-a PE=2 SV=1)

HSP 1 Score: 122.865 bits (307), Expect = 5.207e-28
Identity = 56/96 (58.33%), Postives = 71/96 (73.96%), Query Frame = -3

Query: 1654 RKPNIERNF--PCEFCPAKFSRRDELKRHEKIHSGEKPLSCPYCDKCFMRSDHRTTHIRTHTGEKPYSCDICSKRFARSDEKLRHKRIHLKEKSKK 1935
            + P  ER +  P E C  +FSR DEL RH +IH+G+KP  C  C + F RSDH TTHIRTHTGEKP++CDIC ++FARSDE+ RH +IHL++K KK
Sbjct:  298 KTPPHERPYGCPVESCDRRFSRSDELTRHIRIHTGQKPFQCRICMRNFSRSDHLTTHIRTHTGEKPFACDICGRKFARSDERKRHTKIHLRQKDKK 393

[Close]

BLAST of early growth response-4 vs. TrEMBL
Match: I1ZI72 (Early growth response-4 OS=Schmidtea mediterranea OX=79327 PE=2 SV=1)

HSP 1 Score: 584.719 bits (1506), Expect = 0.000e+0
Identity = 323/325 (99.38%), Postives = 323/325 (99.38%), Query Frame = -3

Query: 1531 MLLFEKFSESDFDSIETGYTPTGKFGTFFKDTSNVDNLDTPQPLXXXXXXXXXXXXNYLISENRLKKCVDIHDRISNRIRQLXXXXXXXXXXXXXXXXXXSVEYKISRGFGNILLDEGQKNTLNTNSGTSLYISINYKDIHPNINSVSAIQLSSPIEESSIYNRRSQRPPTDNKTLRKQAHEEKAHKIIIRKPNIERNFPCEFCPAKFSRRDELKRHEKIHSGEKPLSCPYCDKCFMRSDHRTTHIRTHTGEKPYSCDICSKRFARSDEKLRHKRIHLKEKSKKNITHEICLKLMSQANMENSNKIESKLFPHSSNTLIDLGLQI 2505
            MLLFEKFSESDFDSIETGYTPTGKFGTFFKDTSNVDNLDTPQPLEDNSFEFEDFSFNYLISENRLKKCVDIHDRISNRIRQLSCTSSISCSSSQSCD TTSVEYKISRGFGNILLDEGQKNTLNTNSGTSLYISINYKDIHPNINSVSAIQLSSPIEESSIYNRRSQRPPTDNKTLRKQAHEEKAHKIIIRKPNIERNFPCEFCPAKFSRRDELKRHEKIHSGEKPLSCPYCDKCFMRSDHRTTHIRTHTGEKPYSCDICSKRFARSDEKLRHKRIHLKEKSKKNITHEICLKLMSQANMENSNK ESKLFPHSSNTLIDLGLQI
Sbjct:    1 MLLFEKFSESDFDSIETGYTPTGKFGTFFKDTSNVDNLDTPQPLEDNSFEFEDFSFNYLISENRLKKCVDIHDRISNRIRQLSCTSSISCSSSQSCDXTTSVEYKISRGFGNILLDEGQKNTLNTNSGTSLYISINYKDIHPNINSVSAIQLSSPIEESSIYNRRSQRPPTDNKTLRKQAHEEKAHKIIIRKPNIERNFPCEFCPAKFSRRDELKRHEKIHSGEKPLSCPYCDKCFMRSDHRTTHIRTHTGEKPYSCDICSKRFARSDEKLRHKRIHLKEKSKKNITHEICLKLMSQANMENSNKFESKLFPHSSNTLIDLGLQI 325

[Close]

BLAST of early growth response-4 vs. TrEMBL
Match: X1XEL1 (Uncharacterized protein OS=Acyrthosiphon pisum OX=7029 PE=4 SV=1)

HSP 1 Score: 87.4261 bits (215), Expect = 1.440e-35
Identity = 44/100 (44.00%), Postives = 63/100 (63.00%), Query Frame = -3

Query:  373 EATNVTTQTAAKIKSEAISILGKMECFKFICSLIVWYDILSQINITRKVLQKENFNVSEATTIFSNNIDYLKKYITDDKFNEVIEEAKNIAQHLEIEPEF 672
            E   +   T  K ++EA SI  K+  FKF+C L++WYDIL +IN T K+LQ  + N+SE  T   N I +LK+Y TD+ F + +E+AK +A  L+IE  F
Sbjct:  181 EDLTLVNATGVKCRAEAKSIAEKLVDFKFLCCLVIWYDILFEINHTSKLLQSVSLNISETITQLKNTIIFLKEYRTDEGFQKTLEQAKTLANELQIEANF 280

HSP 2 Score: 58.9214 bits (141), Expect = 1.440e-35
Identity = 39/89 (43.82%), Postives = 56/89 (62.92%), Query Frame = -1

Query:   87 SYEHPDEVINDAAQNFKNIFFNNILDQAIVSSSDRFTLIQEHSTNFNFIYNFKAEMID-EDLRKICMDLEILLV--DGYQKNISDSDLY 344
            +YE  DE I+D  Q+FK  FF+ ILD AI S ++RF+ + +HS  F+F+YN   E+ D ++L K C DL+I L   DG   +I   +LY
Sbjct:  294 AYESQDEPIHDPKQSFKINFFHQILDSAIQSINERFSQLTDHSDLFSFLYNI-TEISDFDELMKKCKDLKIALTSSDGLSLDIIAVELY 381

HSP 3 Score: 55.8398 bits (133), Expect = 1.440e-35
Identity = 25/47 (53.19%), Postives = 34/47 (72.34%), Query Frame = -1

Query:  738 LAVNDAASCCIEAVTFFDIVQR---FFSSSTQRWDIFKKCK*AVALK 869
            L +NDAA+CC++AV FF ++Q    FFS ST RWD+FKK   ++ LK
Sbjct:  102 LVLNDAANCCLDAVKFFGLIQEIYVFFSGSTHRWDVFKKHVNSLTLK 148

[Close]

BLAST of early growth response-4 vs. TrEMBL
Match: H9CXV3 (EGR-1 OS=Schmidtea mediterranea OX=79327 PE=2 SV=1)

HSP 1 Score: 136.346 bits (342), Expect = 9.668e-31
Identity = 67/130 (51.54%), Postives = 91/130 (70.00%), Query Frame = -3

Query: 1654 PIEESSIYNRRSQRPPTDNKTLRKQAHEEKAHKIIIRKPNIERNFPCEFCPAKFSRRDELKRHEKIHSGEKPLSCPYCDKCFMRSDHRTTHIRTHTGEKPYSCDICSKRFARSDEKLRHKRIHLKEKSKK 2043
            P++ S I N+ + +    +  +   + EEK+      +   +++F C  CP++F+R+DEL+RHEKIH+G K L CPYCDK F+RSDHR THIRTHTGEKPYSC+IC K FARSDE+ RH RIH K+  +K
Sbjct:  138 PLDSSQISNQTNIKLEPLHDPISTISREEKSKSGKSNQLPPDKSFTCSNCPSRFTRKDELRRHEKIHTGIKTLCCPYCDKTFIRSDHRRTHIRTHTGEKPYSCEICCKCFARSDERTRHTRIHSKDPVRK 267

[Close]

BLAST of early growth response-4 vs. TrEMBL
Match: A0A4Y1LSX9 (Early growth response 1 OS=Octopus vulgaris OX=6645 GN=Egr1 PE=2 SV=1)

HSP 1 Score: 137.887 bits (346), Expect = 5.655e-30
Identity = 60/96 (62.50%), Postives = 74/96 (77.08%), Query Frame = -3

Query: 1654 RKPNIERNFPC--EFCPAKFSRRDELKRHEKIHSGEKPLSCPYCDKCFMRSDHRTTHIRTHTGEKPYSCDICSKRFARSDEKLRHKRIHLKEKSKK 1935
            + P  ER +PC  E C  +FSR DEL RH +IH+G+KP  CP C + F RSDH TTH+RTHTGEKP+SCDIC ++FARSDEK RH ++HLK+KSKK
Sbjct:  459 KVPPHERPYPCPVEICDRRFSRSDELTRHMRIHTGQKPFQCPICTRSFSRSDHLTTHVRTHTGEKPFSCDICGRKFARSDEKKRHFKVHLKQKSKK 554

[Close]

BLAST of early growth response-4 vs. TrEMBL
Match: A0A0L8IBN0 (Uncharacterized protein OS=Octopus bimaculoides OX=37653 GN=OCBIM_22022722mg PE=4 SV=1)

HSP 1 Score: 137.502 bits (345), Expect = 7.414e-30
Identity = 60/96 (62.50%), Postives = 74/96 (77.08%), Query Frame = -3

Query: 1654 RKPNIERNFPC--EFCPAKFSRRDELKRHEKIHSGEKPLSCPYCDKCFMRSDHRTTHIRTHTGEKPYSCDICSKRFARSDEKLRHKRIHLKEKSKK 1935
            + P  ER +PC  E C  +FSR DEL RH +IH+G+KP  CP C + F RSDH TTH+RTHTGEKP+SCDIC ++FARSDEK RH ++HLK+KSKK
Sbjct:  458 KVPPHERPYPCPVEICDRRFSRSDELTRHMRIHTGQKPFQCPICTRSFSRSDHLTTHVRTHTGEKPFSCDICGRKFARSDEKKRHFKVHLKQKSKK 553

[Close]

BLAST of early growth response-4 vs. Ensembl Cavefish
Match: egr4 (early growth response protein 1-B [Source:NCBI gene;Acc:103025429])

HSP 1 Score: 117.472 bits (293), Expect = 3.823e-28
Identity = 51/92 (55.43%), Postives = 68/92 (73.91%), Query Frame = -3

Query: 1651 ERNFPC--EFCPAKFSRRDELKRHEKIHSGEKPLSCPYCDKCFMRSDHRTTHIRTHTGEKPYSCDICSKRFARSDEKLRHKRIHLKEKSKKN 1920
            E+ FPC  E C  +FSR DEL RH ++H+G +P  C  C + F RSDH TTH+RTHTGEKP+SCD+C +RFARSDE+ RH R+H+K++ +  
Sbjct:  234 EKPFPCPVENCERRFSRSDELNRHVRVHTGHRPFQCRVCSRRFGRSDHLTTHMRTHTGEKPFSCDVCGRRFARSDERKRHARVHIKQRERAQ 325

[Close]

BLAST of early growth response-4 vs. Ensembl Cavefish
Match: egr2b (early growth response 2 [Source:NCBI gene;Acc:103046494])

HSP 1 Score: 118.627 bits (296), Expect = 4.421e-28
Identity = 55/97 (56.70%), Postives = 71/97 (73.20%), Query Frame = -3

Query: 1651 RKPNIERNFPC--EFCPAKFSRRDELKRHEKIHSGEKPLSCPYCDKCFMRSDHRTTHIRTHTGEKPYSCDICSKRFARSDEKLRHKRIHLKEKSKKN 1935
            + P  ER +PC  E C  +FSR DEL RH +IH+G KP  C  C + F RSDH TTHIRTHTGEKP++CD C ++FARSDE+ RH +IHL++K +K+
Sbjct:  288 KTPVHERPYPCPAEGCDRRFSRSDELTRHIRIHTGHKPFQCRICMRNFSRSDHLTTHIRTHTGEKPFACDFCGRKFARSDERKRHTKIHLRQKERKS 384

[Close]

BLAST of early growth response-4 vs. Ensembl Cavefish
Match: egr4 (early growth response protein 1-B [Source:NCBI gene;Acc:103025429])

HSP 1 Score: 117.472 bits (293), Expect = 7.832e-28
Identity = 51/92 (55.43%), Postives = 68/92 (73.91%), Query Frame = -3

Query: 1651 ERNFPC--EFCPAKFSRRDELKRHEKIHSGEKPLSCPYCDKCFMRSDHRTTHIRTHTGEKPYSCDICSKRFARSDEKLRHKRIHLKEKSKKN 1920
            E+ FPC  E C  +FSR DEL RH ++H+G +P  C  C + F RSDH TTH+RTHTGEKP+SCD+C +RFARSDE+ RH R+H+K++ +  
Sbjct:  273 EKPFPCPVENCERRFSRSDELNRHVRVHTGHRPFQCRVCSRRFGRSDHLTTHMRTHTGEKPFSCDVCGRRFARSDERKRHARVHIKQRERAQ 364

[Close]

BLAST of early growth response-4 vs. Ensembl Cavefish
Match: egr3 (early growth response 3 [Source:NCBI gene;Acc:103035480])

HSP 1 Score: 117.472 bits (293), Expect = 1.602e-27
Identity = 52/85 (61.18%), Postives = 64/85 (75.29%), Query Frame = -3

Query: 1654 PCEFCPAKFSRRDELKRHEKIHSGEKPLSCPYCDKCFMRSDHRTTHIRTHTGEKPYSCDICSKRFARSDEKLRHKRIHLKEKSKK 1908
            P E C  +FSR DEL RH +IH+G KP  C  C + F RSDH TTHIRTHTGEKP+SC+ C ++FARSDE+ RH ++HLK+K KK
Sbjct:  305 PAENCDRRFSRSDELTRHLRIHTGHKPFQCRICMRSFSRSDHLTTHIRTHTGEKPFSCEFCGRKFARSDERKRHAKVHLKQKDKK 389

HSP 2 Score: 55.4546 bits (132), Expect = 1.704e-7
Identity = 25/57 (43.86%), Postives = 32/57 (56.14%), Query Frame = -3

Query: 1747 RNFPCEFCPAKFSRRDELKRHEKIHSGEKPLSCPYCDKCFMRSDHRTTHIRTHTGEK 1917
            + F C  C   FSR D L  H + H+GEKP SC +C + F RSD R  H + H  +K
Sbjct:  330 KPFQCRICMRSFSRSDHLTTHIRTHTGEKPFSCEFCGRKFARSDERKRHAKVHLKQK 386

[Close]

BLAST of early growth response-4 vs. Ensembl Cavefish
Match: EGR2 (early growth response protein 2b-like [Source:NCBI gene;Acc:103032442])

HSP 1 Score: 115.546 bits (288), Expect = 4.274e-27
Identity = 51/96 (53.12%), Postives = 69/96 (71.88%), Query Frame = -3

Query: 1654 RKPNIERNFPC--EFCPAKFSRRDELKRHEKIHSGEKPLSCPYCDKCFMRSDHRTTHIRTHTGEKPYSCDICSKRFARSDEKLRHKRIHLKEKSKK 1935
            + P  ER +PC  E C  +FSR DEL RH ++H+G KP  C  C + F RSDH TTHIRTHTGEKP++CD+C ++FARSDE+ RH +IH ++  ++
Sbjct:  269 KTPVHERPYPCPAEGCDRRFSRSDELARHVRVHTGHKPFQCRICMRSFGRSDHLTTHIRTHTGEKPFACDLCGRKFARSDERRRHAKIHQRQSERR 364

[Close]

BLAST of early growth response-4 vs. Ensembl Sea Lamprey
Match: egr4 (early growth response 4 [Source:ZFIN;Acc:ZDB-GENE-080204-90])

HSP 1 Score: 117.472 bits (293), Expect = 1.657e-29
Identity = 55/93 (59.14%), Postives = 67/93 (72.04%), Query Frame = -3

Query: 1663 RKPNIERNFPC--EFCPAKFSRRDELKRHEKIHSGEKPLSCPYCDKCFMRSDHRTTHIRTHTGEKPYSCDICSKRFARSDEKLRHKRIHLKEK 1935
            + P   R FPC  E C  +FSR DEL RH +IH+G KP +C  C + F RSDH TTH+RTHTGEKP++CD C +RFARSDE+ RH RIHLK +
Sbjct:  164 KTPPHARPFPCPAEGCDRRFSRTDELTRHIRIHTGHKPFTCRICMRSFSRSDHLTTHVRTHTGEKPFACDFCGRRFARSDERKRHGRIHLKGR 256

[Close]

BLAST of early growth response-4 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000007569.1 (pep scaffold:Pmarinus_7.0:GL477836:135382:139743:-1 gene:ENSPMAG00000006836.1 transcript:ENSPMAT00000007569.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 87.8113 bits (216), Expect = 1.846e-19
Identity = 40/86 (46.51%), Postives = 51/86 (59.30%), Query Frame = -3

Query: 1663 ERNFPCEFCPAKFSRRDELKRHEKIHSGEKPLSCPYCDKCFMRSDHRTTHIRTHTGEKPYSCDICSKRFARSDEKLRHKRIHLKEK 1920
            ER F C  C   F  +  L+RH+K H GE P  C +C + FM       H+R HTGE+PY+CD C +RF RSD   RH+RIH  E+
Sbjct:  115 ERPFSCRDCGMTFRLKQHLRRHQKTHEGEAPFRCDHCGRLFMHKRSLRIHVRNHTGERPYACDFCDQRFLRSDNLTRHRRIHTGER 200

HSP 2 Score: 71.2478 bits (173), Expect = 7.240e-14
Identity = 34/80 (42.50%), Postives = 51/80 (63.75%), Query Frame = -3

Query: 1681 ERNFPCEFCPAKFSRRDELKRHEKIHSGEKPLSCPYCDKCFMRSDHRTTHIRTHTGEKPYSCDICSKRFARSDEKLRHKR 1920
            E  F C+ C   F  +  L+ H + H+GE+P +C +CD+ F+RSD+ T H R HTGE+P+ C+ C KRF+ S    +H+R
Sbjct:  143 EAPFRCDHCGRLFMHKRSLRIHVRNHTGERPYACDFCDQRFLRSDNLTRHRRIHTGERPFGCERCGKRFSCSHHLTQHRR 222

HSP 3 Score: 70.8626 bits (172), Expect = 1.053e-13
Identity = 35/92 (38.04%), Postives = 53/92 (57.61%), Query Frame = -3

Query: 1675 KIIIRKPNIERNFPCEFCPAKFSRRDELKRHEKIHSGEKPLSCPYCDKCFMRSDHRTTHIRTHTGEKPYSCDICSKRFARSDEKLR-HKRIH 1947
            +I +R    ER + C+FC  +F R D L RH +IH+GE+P  C  C K F  S H T H R+ T   P++C +C + F +  + L  H+++H
Sbjct:  162 RIHVRNHTGERPYACDFCDQRFLRSDNLTRHRRIHTGERPFGCERCGKRFSCSHHLTQHRRSCTMTAPFTCTLCGQMFGKKSDSLGYHQQLH 253

HSP 4 Score: 63.929 bits (154), Expect = 2.340e-11
Identity = 36/87 (41.38%), Postives = 49/87 (56.32%), Query Frame = -3

Query: 1663 ERNFPCEFCPAKFSRRDELKRHEKIHSGE-KPLSCPYCDKCFMRSDHRTTHIRTHTGEKPYSCDICSKRFARSDEKLRHKRIHLKEK 1920
            E+ F CE C  +F+  + L RH +IH+GE KP  C  C   F        H RTHTG   Y+C+ C K+F+ S +  RH+RIH  E+
Sbjct:   30 EKPFACEKCGRRFTWSNSLARHRRIHTGESKPFQCGDCGHRFRNVISFRRHQRTHTGVNLYACEDCGKKFSLSHDLTRHRRIHTGER 116

HSP 5 Score: 62.7734 bits (151), Expect = 5.647e-11
Identity = 34/79 (43.04%), Postives = 43/79 (54.43%), Query Frame = -3

Query: 1675 PCEFCPAKFSRRDELKRHEKIHSGEKPLSCPYCDKCFMRSDHRTTHIRTHTGE-KPYSCDICSKRFARSDEKLRHKRIH 1908
             CE C A F +  E+ RH +IH+GEKP +C  C + F  S+    H R HTGE KP+ C  C  RF       RH+R H
Sbjct:    6 ACEVCGALFRKACEVTRHRRIHTGEKPFACEKCGRRFTWSNSLARHRRIHTGESKPFQCGDCGHRFRNVISFRRHQRTH 84

HSP 6 Score: 50.447 bits (119), Expect = 7.012e-7
Identity = 24/58 (41.38%), Postives = 34/58 (58.62%), Query Frame = -3

Query: 1666 GEKPLSCPYCDKCFMRSDHRTTHIRTHTGEKPYSCDICSKRFARSDEKLRHKRIHLKE 1839
            G+   +C  C   F ++   T H R HTGEKP++C+ C +RF  S+   RH+RIH  E
Sbjct:    1 GKMRHACEVCGALFRKACEVTRHRRIHTGEKPFACEKCGRRFTWSNSLARHRRIHTGE 58

HSP 7 Score: 49.2914 bits (116), Expect = 1.349e-6
Identity = 29/82 (35.37%), Postives = 39/82 (47.56%), Query Frame = -3

Query: 1666 FPCEFCPAKFSRRDELKRHEKIHSGEKPLSCPYCDKCFMRSDHRTTHIRTHTGEKPYSCDICSKRFARSDEKLRHKRIHLKE 1911
            F C  C  +F      +RH++ H+G    +C  C K F  S   T H R HTGE+P+SC  C   F       RH++ H  E
Sbjct:   62 FQCGDCGHRFRNVISFRRHQRTHTGVNLYACEDCGKKFSLSHDLTRHRRIHTGERPFSCRDCGMTFRLKQHLRRHQKTHEGE 143

[Close]

BLAST of early growth response-4 vs. Ensembl Sea Lamprey
Match: wt1a (WT1 transcription factor a [Source:ZFIN;Acc:ZDB-GENE-980526-558])

HSP 1 Score: 88.5817 bits (218), Expect = 2.351e-19
Identity = 58/158 (36.71%), Postives = 85/158 (53.80%), Query Frame = -3

Query: 1648 INSVSAIQLSSPIEESSIYNRRSQRP-----PTDNKTLRKQAHEEKAHKIIIRKPNIERNFPCEF--CPAKFSRRDELKRHEKIHSGE---KPLSCPYCDKCFMRSDHRTTHIRTHTG---EKPYSCDI--CSKRFARSDEKLRHKRIHLKEKSKKNI 2076
            ++  ++  L+  +   S   R  +RP     P  +K   K +H +    +  RK   ER + C++  C  +FSR D+LKRH++ H+G    KP  C  CD+ F RSDH  TH RTHTG   EKP+ C    C K+FARSDE +RH  +H +  +K  +
Sbjct:  145 VSGAASGALTQAVGAPSGRGRADRRPYMCNYPGCSKRYFKLSHLQ----MHCRKHTGERPYQCDYKDCGRRFSRSDQLKRHQRRHTGVTGVKPFQCKMCDRKFARSDHLKTHTRTHTGKPSEKPFVCRWPNCQKKFARSDELVRHHNMHQRNVAKLQL 298

HSP 2 Score: 53.5286 bits (127), Expect = 9.318e-8
Identity = 28/79 (35.44%), Postives = 43/79 (54.43%), Query Frame = -3

Query: 1609 KPLSC--PYCDKCFMRSDHRTTHIRTHTGEKPYSCDI--CSKRFARSDEKLRHKRIHLKEKSKKNITHEICLKLMSQAN 1833
            +P  C  P C K + +  H   H R HTGE+PY CD   C +RF+RSD+  RH+R H      K    ++C +  ++++
Sbjct:  169 RPYMCNYPGCSKRYFKLSHLQMHCRKHTGERPYQCDYKDCGRRFSRSDQLKRHQRRHTGVTGVKPFQCKMCDRKFARSD 247

[Close]

BLAST of early growth response-4 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000000923.1 (pep scaffold:Pmarinus_7.0:GL480775:18221:19434:-1 gene:ENSPMAG00000000839.1 transcript:ENSPMAT00000000923.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 80.1073 bits (196), Expect = 2.061e-18
Identity = 34/86 (39.53%), Postives = 49/86 (56.98%), Query Frame = -3

Query: 1681 IRKPNIERNFPCEFCPAKFSRRDELKRHEKIHSGEKPLSCPYCDKCFMRSDHRTTHIRTHTGEKPYSCDICSKRFARSDEKLRHKR 1938
            IR    ER + C  C  +F+R    +RH ++H+GE+P +C  C + F +  H   H R HTGE+PY+C  C +RFA+     RH R
Sbjct:   13 IRNHTGERPYACGDCGRRFARGANEERHRRVHTGERPYACAACGRRFRQKPHLAAHTRLHTGERPYACAACGRRFAKPYSLTRHLR 98

HSP 2 Score: 60.4622 bits (145), Expect = 1.921e-11
Identity = 24/61 (39.34%), Postives = 35/61 (57.38%), Query Frame = -3

Query: 1663 HSGEKPLSCPYCDKCFMRSDHRTTHIRTHTGEKPYSCDICSKRFARSDEKLRHKRIHLKEK 1845
            H+GE+P +C  C + F R  +   H R HTGE+PY+C  C +RF +      H R+H  E+
Sbjct:   16 HTGERPYACGDCGRRFARGANEERHRRVHTGERPYACAACGRRFRQKPHLAAHTRLHTGER 76

HSP 3 Score: 51.2174 bits (121), Expect = 3.379e-8
Identity = 19/38 (50.00%), Postives = 28/38 (73.68%), Query Frame = -3

Query: 1663 THIRTHTGEKPYSCDICSKRFARSDEKLRHKRIHLKEK 1776
            ++IR HTGE+PY+C  C +RFAR   + RH+R+H  E+
Sbjct:   11 SNIRNHTGERPYACGDCGRRFARGANEERHRRVHTGER 48

HSP 4 Score: 47.7506 bits (112), Expect = 5.002e-7
Identity = 27/92 (29.35%), Postives = 45/92 (48.91%), Query Frame = -3

Query: 1762 SSIYNRRSQRPPTDNKTLRKQAH--EEKAHKIIIRKPNIERNFPCEFCPAKFSRRDELKRHEKIHSGEKPLSCPYCDKCFMRSDHRTTHIRT 2031
            S+I N   +RP       R+ A    E+ H+   R    ER + C  C  +F ++  L  H ++H+GE+P +C  C + F +    T H+R+
Sbjct:   11 SNIRNHTGERPYACGDCGRRFARGANEERHR---RVHTGERPYACAACGRRFRQKPHLAAHTRLHTGERPYACAACGRRFAKPYSLTRHLRS 99

[Close]

BLAST of early growth response-4 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000005004.1 (pep scaffold:Pmarinus_7.0:GL484587:30140:35096:1 gene:ENSPMAG00000004537.1 transcript:ENSPMAT00000005004.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 85.8853 bits (211), Expect = 8.277e-18
Identity = 37/81 (45.68%), Postives = 54/81 (66.67%), Query Frame = -3

Query: 1678 ERNFPCEFCPAKFSRRDELKRHEKIHSGEKPLSCPYCDKCFMRSDHRTTHIRTHTGEKPYSCDICSKRFARSDEKLRHKRI 1920
            E+ + C  C  +F ++  L+RHEKIHSGEKP +C  C   F++  H   H RTH+GEKPY CD C + ++R+D+  +HKR+
Sbjct:   31 EKAYQCSQCTMRFIQKYLLQRHEKIHSGEKPFTCEQCGMRFIQKYHLERHKRTHSGEKPYECDYCHQYYSRTDQLAKHKRM 111

HSP 2 Score: 65.855 bits (159), Expect = 2.408e-11
Identity = 34/85 (40.00%), Postives = 45/85 (52.94%), Query Frame = -3

Query: 1663 RNFPCEFCPAKFSRRDELKRHEKIHSGEKPLSCPYCDKCFMRSDHRTTHIRTHTGEKPYSCDICSKRFARSDEKLRHKRIHLKEK 1917
            + F CE C A F     L+RH  IH+GEK   C  C   F++      H + H+GEKP++C+ C  RF +     RHKR H  EK
Sbjct:    4 KKFVCERCCAAFRTNYHLQRHVLIHTGEKAYQCSQCTMRFIQKYLLQRHEKIHSGEKPFTCEQCGMRFIQKYHLERHKRTHSGEK 88

[Close]

BLAST of early growth response-4 vs. Ensembl Yeast
Match: AZF1 (Zinc-finger transcription factor; involved in diauxic shift; in the presence of glucose, activates transcription of genes involved in growth and carbon metabolism; in nonfermentable carbon sources, activates transcription of genes involved in maintenance of cell wall integrity; relocalizes to the cytosol in response to hypoxia [Source:SGD;Acc:S000005639])

HSP 1 Score: 77.0258 bits (188), Expect = 7.575e-15
Identity = 37/81 (45.68%), Postives = 45/81 (55.56%), Query Frame = -3

Query: 1663 CEFCPAKFSRRDELKRHEKIHSGEKPLSCPYCDKCFMRSDHRTTHIRTHTGEKPYSCDICSKRFARSDEKLRHKRIHLKEK 1905
            C +C   FS+   L+ H + H G KP  C YC K F +  +  TH R HTGEKPYSCDIC K+F+R      H   H K K
Sbjct:  595 CPYCHRLFSQATHLEVHVRSHIGYKPFVCDYCGKRFTQGGNLRTHERLHTGEKPYSCDICDKKFSRKGNLAAHLVTHQKLK 675

HSP 2 Score: 67.3958 bits (163), Expect = 6.736e-12
Identity = 31/82 (37.80%), Postives = 47/82 (57.32%), Query Frame = -3

Query: 1675 FPCEFCPAKFSRRDELKRHEKIHSGEKPLSCPYCDKCFMRSDHRTTHIRTHTGEKPYSCDI--CSKRFAR-SDEKLRHKRIH 1911
            F C++C  +F++   L+ HE++H+GEKP SC  CDK F R  +   H+ TH   KP+ C +  C+K F +  + K    R H
Sbjct:  621 FVCDYCGKRFTQGGNLRTHERLHTGEKPYSCDICDKKFSRKGNLAAHLVTHQKLKPFVCKLENCNKTFTQLGNMKAHQNRFH 702

[Close]

BLAST of early growth response-4 vs. Ensembl Yeast
Match: MIG1 (Transcription factor involved in glucose repression; sequence specific DNA binding protein containing two Cys2His2 zinc finger motifs; regulated by the SNF1 kinase and the GLC7 phosphatase; regulates filamentous growth along with Mig2p in response to glucose depletion; activated in stochastic pulses of nuclear localization, shuttling between cytosol and nucleus depending on external glucose levels and its phosphorylation state [Source:SGD;Acc:S000003003])

HSP 1 Score: 74.3294 bits (181), Expect = 3.217e-14
Identity = 31/57 (54.39%), Postives = 41/57 (71.93%), Query Frame = -3

Query: 1675 GEKPLSCPYCDKCFMRSDHRTTHIRTHTGEKPYSCDI--CSKRFARSDEKLRHKRIH 1839
              +P +CP C + F R +H+T H+R HTGEKP++CD   C KRF+RSDE  RH+RIH
Sbjct:   34 APRPHACPICHRAFHRLEHQTRHMRIHTGEKPHACDFPGCVKRFSRSDELTRHRRIH 90

HSP 2 Score: 52.7582 bits (125), Expect = 1.888e-7
Identity = 30/75 (40.00%), Postives = 36/75 (48.00%), Query Frame = -3

Query: 1744 EEKAHKIIIRKPNIERNFPCEFCPAKFSRRDELKRHEKIHSGEKPLSC--PYCDKCFMRSDHRTTHIRTHTGEKP 1962
            E K+   +  K    R   C  C   F R +   RH +IH+GEKP +C  P C K F RSD  T H R HT   P
Sbjct:   21 ESKSKSKVAAKSEAPRPHACPICHRAFHRLEHQTRHMRIHTGEKPHACDFPGCVKRFSRSDELTRHRRIHTNSHP 95

[Close]

BLAST of early growth response-4 vs. Ensembl Yeast
Match: ZAP1 (Zinc-regulated transcription factor; binds to zinc-responsive promoters to induce transcription of certain genes in presence of zinc, represses other genes in low zinc; regulates its own transcription; contains seven zinc-finger domains [Source:SGD;Acc:S000003592])

HSP 1 Score: 72.4034 bits (176), Expect = 2.377e-13
Identity = 37/82 (45.12%), Postives = 46/82 (56.10%), Query Frame = -3

Query: 1666 FPCEFCPAKFSRRDELKRHEKIHSGEKPLSCPYCDKCFMRSDHRTTHIRTHTGEKPYSCDICSKRFARSDEKLRHKRIHLKE 1911
            + C+ C   FS  + L +H + HSGEKP  C  C+K F  S     HIRTHTGEKP  C IC KRF  S    +H + H K+
Sbjct:  768 YKCKTCKRCFSSEETLVQHTRTHSGEKPYKCHICNKKFAISSSLKIHIRTHTGEKPLQCKICGKRFNESSNLSKHIKTHQKK 849

HSP 2 Score: 71.2478 bits (173), Expect = 4.546e-13
Identity = 36/78 (46.15%), Postives = 44/78 (56.41%), Query Frame = -3

Query: 1663 CPAKFSRRDELKRHEKIHSGEKPLSCPYCDKCFMRSDHRTTHIRTHTGEKPYSCDICSKRFARSDEKLRHKRIHLKEK 1896
            C   F +R +L RH K+HS  KP  C  C +CF   +    H RTH+GEKPY C IC+K+FA S     H R H  EK
Sbjct:  745 CHRTFPQRQKLIRHLKVHSKYKPYKCKTCKRCFSSEETLVQHTRTHSGEKPYKCHICNKKFAISSSLKIHIRTHTGEK 822

HSP 3 Score: 55.8398 bits (133), Expect = 2.511e-8
Identity = 30/69 (43.48%), Postives = 39/69 (56.52%), Query Frame = -3

Query: 1714 ERNFPCEFCPAKFSRRDELKRHEKIHSGEKPLSCPYCDKCFMRSDHRTTHIRTHTGEKPYSCDICSKRF 1920
            E+ + C  C  KF+    LK H + H+GEKPL C  C K F  S + + HI+TH  +K Y C  CSK F
Sbjct:  793 EKPYKCHICNKKFAISSSLKIHIRTHTGEKPLQCKICGKRFNESSNLSKHIKTH--QKKYKCSDCSKSF 859

[Close]

BLAST of early growth response-4 vs. Ensembl Yeast
Match: CRZ1 (Transcription factor, activates transcription of stress response genes; nuclear localization is positively regulated by calcineurin-mediated dephosphorylation; rapidly localizes to the nucleus under blue light stress; can be activated in stochastic pulses of nuclear localization in response to calcium [Source:SGD;Acc:S000004972])

HSP 1 Score: 68.9366 bits (167), Expect = 2.389e-12
Identity = 39/108 (36.11%), Postives = 52/108 (48.15%), Query Frame = -3

Query: 1687 TLRKQAHEEKAHKIIIRKPNIERNFPCEFCPAKFSRRDELKRHEKIHSGEKPLSCPYCDKCFMRSDHRTTHIRTHTGEKPYSCD---------ICSKRFARSDEKLRH 1983
            +++K  + EK   +   + N   NF C+ C  KF+R   LK H + H+ E+P  C  C K F R   R  H   HTG+K Y C           C K+FARSD   RH
Sbjct:  546 SVKKNDNLEKLDSVTNNRKN-PANFACDVCGKKFTRPYNLKSHLRTHTNERPFICSICGKAFARQHDRKRHEDLHTGKKRYVCGGKLKDGKPWGCGKKFARSDALGRH 652

HSP 2 Score: 55.8398 bits (133), Expect = 2.465e-8
Identity = 26/75 (34.67%), Postives = 43/75 (57.33%), Query Frame = -3

Query: 1663 RRDELKRHEKIHSGEKP---LSCPYCDKCFMRSDHRTTHIRTHTGEKPYSCDICSKRFARSDEKLRHKRIHLKEK 1878
            + D L++ + + +  K     +C  C K F R  +  +H+RTHT E+P+ C IC K FAR  ++ RH+ +H  +K
Sbjct:  549 KNDNLEKLDSVTNNRKNPANFACDVCGKKFTRPYNLKSHLRTHTNERPFICSICGKAFARQHDRKRHEDLHTGKK 623

[Close]

BLAST of early growth response-4 vs. Ensembl Yeast
Match: MIG3 (Transcriptional regulator; partially nonfunctional in S288C strains but has a major role in catabolite repression and ethanol response in some other strains; involved in response to toxic agents; phosphorylation by Snf1p or the Mec1p pathway inactivates Mig3p, allowing induction of damage response genesenvironment [Source:SGD;Acc:S000000830])

HSP 1 Score: 62.003 bits (149), Expect = 1.874e-10
Identity = 29/65 (44.62%), Postives = 39/65 (60.00%), Query Frame = -3

Query: 1648 EKPLSCPYCDKCFMRSDHRTTHIRTHTGEKPYSCDI--CSKRFARSDEKLRHKRIHLKEKSKKNI 1836
            ++P  C  C + F R +H+  H RTHTGEKP+ C +  C K F+RSDE  RH R H K   ++ I
Sbjct:   14 QRPFRCEICSRGFHRLEHKKRHGRTHTGEKPHKCTVQGCPKSFSRSDELKRHLRTHTKGVQRRRI 78

HSP 2 Score: 53.5286 bits (127), Expect = 7.605e-8
Identity = 28/59 (47.46%), Postives = 33/59 (55.93%), Query Frame = -3

Query: 1756 NIERNFPCEFCPAKFSRRDELKRHEKIHSGEKPLSCPY--CDKCFMRSDHRTTHIRTHT 1926
            N +R F CE C   F R +  KRH + H+GEKP  C    C K F RSD    H+RTHT
Sbjct:   12 NDQRPFRCEICSRGFHRLEHKKRHGRTHTGEKPHKCTVQGCPKSFSRSDELKRHLRTHT 70

[Close]

BLAST of early growth response-4 vs. Ensembl Nematostella
Match: EDO49112 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RGT8])

HSP 1 Score: 110.153 bits (274), Expect = 6.123e-29
Identity = 50/81 (61.73%), Postives = 62/81 (76.54%), Query Frame = -3

Query: 1666 PCEFCPAKFSRRDELKRHEKIHSGEKPLSCPYCDKCFMRSDHRTTHIRTHTGEKPYSCDICSKRFARSDEKLRHKRIHLKE 1908
            P E CP +FSR DEL RH + H+G+KP  C  C + F RSDH TTHIRTHTGEKP++C+ C +RFARSDE+ RH +IHL+E
Sbjct:    7 PVETCPRRFSRSDELTRHMRTHTGQKPFQCRICMRNFSRSDHLTTHIRTHTGEKPFACETCGRRFARSDERRRHMKIHLRE 87

HSP 2 Score: 59.6918 bits (143), Expect = 3.623e-11
Identity = 30/60 (50.00%), Postives = 38/60 (63.33%), Query Frame = -3

Query: 1663 EKPLSCPY--CDKCFMRSDHRTTHIRTHTGEKPYSCDICSKRFARSDEKLRHKRIHLKEK 1836
            E+P +CP   C + F RSD  T H+RTHTG+KP+ C IC + F+RSD    H R H  EK
Sbjct:    1 ERPYACPVETCPRRFSRSDELTRHMRTHTGQKPFQCRICMRNFSRSDHLTTHIRTHTGEK 60

HSP 3 Score: 50.0618 bits (118), Expect = 9.285e-8
Identity = 25/63 (39.68%), Postives = 34/63 (53.97%), Query Frame = -3

Query: 1750 IRKPNIERNFPCEFCPAKFSRRDELKRHEKIHSGEKPLSCPYCDKCFMRSDHRTTHIRTHTGE 1938
            +R    ++ F C  C   FSR D L  H + H+GEKP +C  C + F RSD R  H++ H  E
Sbjct:   25 MRTHTGQKPFQCRICMRNFSRSDHLTTHIRTHTGEKPFACETCGRRFARSDERRRHMKIHLRE 87

[Close]

BLAST of early growth response-4 vs. Ensembl Nematostella
Match: EDO47692 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RLH7])

HSP 1 Score: 86.6557 bits (213), Expect = 3.840e-20
Identity = 39/82 (47.56%), Postives = 52/82 (63.41%), Query Frame = -3

Query: 1675 ERNFPCEFCPAKFSRRDELKRHEKIHSGEKPLSCPYCDKCFMRSDHRTTHIRTHTGEKPYSCDICSKRFARSDEKLRHKRIH 1920
            E+ F C  C  +FS+   +  H + H+GE+P  C  C+K F  S   T H+RTHTGEKPY C+IC +RF++S    RHKRIH
Sbjct:   47 EKPFRCRVCGRQFSQSSSVTTHMRTHNGERPYKCKVCNKAFADSSTLTKHVRTHTGEKPYQCEICHQRFSQSGNMNRHKRIH 128

HSP 2 Score: 83.9593 bits (206), Expect = 4.251e-19
Identity = 46/113 (40.71%), Postives = 62/113 (54.87%), Query Frame = -3

Query: 1576 FPCEFCPAKFSRRDELKRHEKIHSGEKPLSCPYCDKCFMRSDHRTTHIRTHTGEKPYSCDICSKRFARSDEKLRHKRIHLKEKSKKNITHEICLKLMSQ-ANMENSNKIESKL 1911
            + C  C   F++   L  H +IHSGEKP  C  C + F +S   TTH+RTH GE+PY C +C+K FA S    +H R H  EK  +    EIC +  SQ  NM    +I ++L
Sbjct:   22 YQCMVCLKSFTQAANLTAHFRIHSGEKPFRCRVCGRQFSQSSSVTTHMRTHNGERPYKCKVCNKAFADSSTLTKHVRTHTGEKPYQC---EICHQRFSQSGNMNRHKRIHNEL 131

HSP 3 Score: 63.929 bits (154), Expect = 4.306e-12
Identity = 29/77 (37.66%), Postives = 44/77 (57.14%), Query Frame = -3

Query: 1654 FSRRDELKRHEKIHSGEKPLSCPYCDKCFMRSDHRTTHIRTHTGEKPYSCDICSKRFARSDEKLRHKRIHLKEKSKK 1884
            ++R   L+ H + HSG KP  C  C K F ++ + T H R H+GEKP+ C +C ++F++S     H R H  E+  K
Sbjct:    3 YARLSTLRLHMRTHSGVKPYQCMVCLKSFTQAANLTAHFRIHSGEKPFRCRVCGRQFSQSSSVTTHMRTHNGERPYK 79

[Close]

BLAST of early growth response-4 vs. Ensembl Nematostella
Match: EDO29702 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T2W2])

HSP 1 Score: 85.5001 bits (210), Expect = 2.302e-18
Identity = 49/131 (37.40%), Postives = 73/131 (55.73%), Query Frame = -3

Query: 1558 KIIIRKPNIERNFPCEFCPAKFSRRDELKRHEKIHSGEKPLSCPYCDKCFMRSDHRTTHIRTHTGEKPYSCDICSKRFARSDEKLRHKRIHLKEKSKKNITHEICLKLMSQ-ANMENSNKIESKLFPHSSN 1947
            K  +R  + ++ + C+ C   F +  +LKRH KIH+G+KP  C  C KCF RS+   TH+R H+G+KPY CD+C K F+ S    RH  IH  +K  K    ++C K  S+  N++    I S   P+  +
Sbjct:   80 KTHLRIHSGQKPYKCDECGKCFIQYVDLKRHLKIHTGQKPYECGECGKCFTRSERLKTHLRIHSGQKPYKCDVCGKCFSESRNLKRHLMIHSGQKPYKC---DVCGKCFSESGNLKKHLMIHSGQKPYKCD 207

HSP 2 Score: 76.6406 bits (187), Expect = 2.505e-15
Identity = 36/86 (41.86%), Postives = 53/86 (61.63%), Query Frame = -3

Query: 1663 ERNFPCEFCPAKFSRRDELKRHEKIHSGEKPLSCPYCDKCFMRSDHRTTHIRTHTGEKPYSCDICSKRFARSDEKLRHKRIHLKEK 1920
            ++ + C+ C   F++   L RH +IHSG+KP  C  C KCF +S +  TH+R H+G+KPY CD C K F +  +  RH +IH  +K
Sbjct:   33 QKPYRCDECGKGFTQSGALNRHLRIHSGQKPYKCDECGKCFNQSANLKTHLRIHSGQKPYKCDECGKCFIQYVDLKRHLKIHTGQK 118

HSP 3 Score: 74.3294 bits (181), Expect = 1.428e-14
Identity = 44/129 (34.11%), Postives = 69/129 (53.49%), Query Frame = -3

Query: 1555 IRKPNIERNFPCEFCPAKFSRRDELKRHEKIHSGEKPLSCPYCDKCFMRSDHRTTHIRTHTGEKPYSCDICSKRFARSDEKLRHKRIHLKEKSKKNITHEICLKLMSQA-NMENSNKIESKLFPHSSNT 1938
            +R  + ++ + C+ C   F++   LK H +IHSG+KP  C  C KCF++      H++ HTG+KPY C  C K F RS+    H RIH  +K  K    ++C K  S++ N++    I S   P+  + 
Sbjct:   55 LRIHSGQKPYKCDECGKCFNQSANLKTHLRIHSGQKPYKCDECGKCFIQYVDLKRHLKIHTGQKPYECGECGKCFTRSERLKTHLRIHSGQKPYKC---DVCGKCFSESRNLKRHLMIHSGQKPYKCDV 180

HSP 4 Score: 70.0922 bits (170), Expect = 3.282e-13
Identity = 38/84 (45.24%), Postives = 46/84 (54.76%), Query Frame = -3

Query: 1654 CEFCPAKFSRRDELKRHEKIHSGEKPLSCPYCDKCFMRSDHRTTHIRTHTGEKPYSCDICSKRFARSDEKLRHKRIHLKEKSKK 1905
            C  C   F+R   LKRH  IHSG+KP  C  C K F +S     H+R H+G+KPY CD C K F +S     H RIH  +K  K
Sbjct:   10 CGECGMGFTRHAYLKRHLMIHSGQKPYRCDECGKGFTQSGALNRHLRIHSGQKPYKCDECGKCFNQSANLKTHLRIHSGQKPYK 93

HSP 5 Score: 67.781 bits (164), Expect = 2.313e-12
Identity = 33/78 (42.31%), Postives = 44/78 (56.41%), Query Frame = -3

Query: 1714 KIIIRKPNIERNFPCEFCPAKFSRRDELKRHEKIHSGEKPLSCPYCDKCFMRSDHRTTHIRTHTGEKPYSCDICSKRF 1947
            K  +R  + ++ + C+ C   FS    LKRH  IHSG+KP  C  C KCF  S +   H+  H+G+KPY CD C K F
Sbjct:  136 KTHLRIHSGQKPYKCDVCGKCFSESRNLKRHLMIHSGQKPYKCDVCGKCFSESGNLKKHLMIHSGQKPYKCDECGKCF 213

HSP 6 Score: 59.6918 bits (143), Expect = 9.844e-10
Identity = 30/75 (40.00%), Postives = 43/75 (57.33%), Query Frame = -3

Query: 1705 ERNFPCEFCPAKFSRRDELKRHEKIHSGEKPLSCPYCDKCFMRSDHRTTHI---RTHTGEKPYSCDICSKRFARS 1920
            ++ + C+ C   FS    LK+H  IHSG+KP  C  C KCF+   +  TH+     H+G+KP+ CD C K F +S
Sbjct:  173 QKPYKCDVCGKCFSESGNLKKHLMIHSGQKPYKCDECGKCFILYRNLKTHLIHLMIHSGQKPHKCDECGKCFHQS 247

[Close]

BLAST of early growth response-4 vs. Ensembl Nematostella
Match: EDO45259 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RTG0])

HSP 1 Score: 81.2629 bits (199), Expect = 4.788e-18
Identity = 44/103 (42.72%), Postives = 54/103 (52.43%), Query Frame = -3

Query: 1609 RNFPCEFCPAKFSRRDELKRHEKIHSGEKPLSCPYCDKCFMRSDHRTTHIRTHTGEKPYSCDICSKRFARSDEKLRHKRIHLKEKSKKNITHEICLKLMSQAN 1917
            R + C FC   F     L+RH + H+GE P  C  C + F+RS     H+R HTGEKPY C  CS+ FARS +  RH R H  EK  K      C K  SQ+ 
Sbjct:   33 RTWKCSFCSKAFQYPCYLRRHMRSHTGESPYKCTQCSRAFVRSTDLQRHLRNHTGEKPYKCKECSRAFARSTDLKRHMRTHTGEKPYKCWQ---CSKAFSQSG 132

HSP 2 Score: 70.0922 bits (170), Expect = 3.543e-14
Identity = 37/88 (42.05%), Postives = 47/88 (53.41%), Query Frame = -3

Query: 1675 IRKPNIERNFPCEFCPAKFSRRDELKRHEKIHSGEKPLSCPYCDKCFMRSDHRTTHIRTHTGEKPYSCDICSKRFARSDEKLRHKRIH 1938
            +R    E  + C  C   F R  +L+RH + H+GEKP  C  C + F RS     H+RTHTGEKPY C  CSK F++S     H   H
Sbjct:   54 MRSHTGESPYKCTQCSRAFVRSTDLQRHLRNHTGEKPYKCKECSRAFARSTDLKRHMRTHTGEKPYKCWQCSKAFSQSGSLQTHLHTH 141

[Close]

BLAST of early growth response-4 vs. Ensembl Nematostella
Match: EDO45483 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RSV6])

HSP 1 Score: 87.4261 bits (215), Expect = 8.187e-18
Identity = 58/155 (37.42%), Postives = 77/155 (49.68%), Query Frame = -3

Query: 1609 IEESSI-YNRRS------QRPPTDNK---TLRKQAHEEKAHKIIIRKPNI-ERNFPCEFCPAKFSRRDELKRHEKIHSGEKPLSCPYCDKCFMRSDHRTTHIRTHTGEKPYSCDICSKRFARSDEKLRHKRIHLKEKSKKNITHEICLKLMSQAN 2040
            IEESS  Y + S      QRPP        L  +   +  H+ + R+ ++ ER + CE C   F+    LKRH   H+GEKP  CP C KCF ++    TH  THTGEKP+ C  C K FA++    RH   H  EK ++      C K  +QA 
Sbjct:   34 IEESSTKYTQESEELDKRQRPPKKRSFECDLCGKCFSQSGHRNVHRRTHLGERPYKCEQCGKYFAHAGNLKRHALTHTGEKPHQCPQCGKCFAQAGDLKTHALTHTGEKPHQCPQCGKFFAQAGHLKRHAFTHTGEKPQQCPQ---CGKFFAQAG 185

HSP 2 Score: 77.7962 bits (190), Expect = 7.232e-15
Identity = 42/101 (41.58%), Postives = 52/101 (51.49%), Query Frame = -3

Query: 1618 ERNFPCEFCPAKFSRRDELKRHEKIHSGEKPLSCPYCDKCFMRSDHRTTHIRTHTGEKPYSCDICSKRFARSDEKLRHKRIHLKEKSKKNITHEICLKLMS 1920
            E+   C  C   F+R  +LKRH   H+GEKP  CP C KCF  +    TH  THTGEKP+ C  C K FA++ +  RH   H  EK  +      C  L S
Sbjct:  288 EKPHQCPQCGKFFARAGDLKRHALTHTGEKPHQCPQCGKCFALASSLKTHALTHTGEKPHQCPQCGKCFAQAGDLKRHALTHTGEKPHQCPQCGKCFALAS 388

HSP 3 Score: 77.0258 bits (188), Expect = 1.253e-14
Identity = 47/122 (38.52%), Postives = 61/122 (50.00%), Query Frame = -3

Query: 1618 QAHEEKAHKIIIRKPNI----ERNFPCEFCPAKFSRRDELKRHEKIHSGEKPLSCPYCDKCFMRSDHRTTHIRTHTGEKPYSCDICSKRFARSDEKLRHKRIHLKEKSKKNITHEICLKLMS 1971
            QA   K H   I++  +    E+   C  C   F++  +LKRH   H+GEKP  CP C K F ++ H  TH  THTGEKP+ C  C K FAR+ +  RH   H  EK  +      C  L S
Sbjct:  211 QASSRKTHARHIQRHALTHTGEKPQQCPQCGKCFAQAGDLKRHALTHTGEKPHQCPQCGKYFAQARHLKTHALTHTGEKPHQCPQCGKFFARAGDLKRHALTHTGEKPHQCPQCGKCFALAS 332

HSP 4 Score: 70.4774 bits (171), Expect = 1.385e-12
Identity = 43/106 (40.57%), Postives = 53/106 (50.00%), Query Frame = -3

Query: 1609 ERNFPCEFCPAKFSRRDELKRHEKIHSGEKPLSCPYCDKCFMRSDHRTTHIRTHTGEKPYSCDICSKRFARSDEKLRHKRIHLKEKSKKNITHEI--CLKLMSQAN 1920
            E+   C  C   F++  +LKRH   H+GEKP  CP C KCF  +    TH  THTGEKP+ C  C K FA +     H   H  EK     TH+   C K  +QA 
Sbjct:  344 EKPHQCPQCGKCFAQAGDLKRHALTHTGEKPHQCPQCGKCFALASSLKTHALTHTGEKPHRCPQCGKCFALASSLNIHALKHTGEK-----THQCPQCGKFFAQAG 444

HSP 5 Score: 67.3958 bits (163), Expect = 1.516e-11
Identity = 39/105 (37.14%), Postives = 48/105 (45.71%), Query Frame = -3

Query: 1606 ERNFPCEFCPAKFSRRDELKRHEKIHSGEKPLSCPYCDKCFMRSDHRTTHIRTHTGEKPYSCDICSKRFARSDEKLRHKRIHLKEKSKKNITHEICLKLMSQANM 1920
            E+   C  C   F+    LK H   H+GEKP  CP C KCF ++     H  THTGEKP+ C  C K FA +     H   H  EK  +      C  L S  N+
Sbjct:  316 EKPHQCPQCGKCFALASSLKTHALTHTGEKPHQCPQCGKCFAQAGDLKRHALTHTGEKPHQCPQCGKCFALASSLKTHALTHTGEKPHRCPQCGKCFALASSLNI 420

HSP 6 Score: 64.6994 bits (156), Expect = 1.150e-10
Identity = 40/111 (36.04%), Postives = 53/111 (47.75%), Query Frame = -3

Query: 1609 ERNFPCEFCPAKFSRRDELKRHEKIHSGEKPLSCPYCDKCFMRSDHRTTHIRTHTGEKPYSCDICSKRFARSDEKLRHKR-------IHLKEKSKKNITHEICLKLMSQAN 1920
            E+   C  C   F++   LKRH   H+GEKP  CP C K F ++     H  THTGEKP+ C  C K FA++  +  H R        H  EK ++      C K  +QA 
Sbjct:  141 EKPHQCPQCGKFFAQAGHLKRHAFTHTGEKPQQCPQCGKFFAQAGDLKRHALTHTGEKPHQCPQCGKFFAQASSRKTHARHIQRHALTHTGEKPQQCPQ---CGKCFAQAG 248

HSP 7 Score: 63.1586 bits (152), Expect = 2.753e-10
Identity = 39/104 (37.50%), Postives = 48/104 (46.15%), Query Frame = -3

Query: 1609 ERNFPCEFCPAKFSRRDELKRHEKIHSGEKPLSCPYCDKCFMRSDHRTTHIRTHTGEKPYSCDICSKRFARSDEKLRHKRIHLKEKSKKNITHEICLKLMSQAN 1920
            E+   C  C   F++   LK H   H+GEKP  CP C K F R+     H  THTGEKP+ C  C K FA +     H   H  EK  +      C K  +QA 
Sbjct:  260 EKPHQCPQCGKYFAQARHLKTHALTHTGEKPHQCPQCGKFFARAGDLKRHALTHTGEKPHQCPQCGKCFALASSLKTHALTHTGEKPHQCPQ---CGKCFAQAG 360

HSP 8 Score: 63.1586 bits (152), Expect = 2.925e-10
Identity = 32/74 (43.24%), Postives = 39/74 (52.70%), Query Frame = -3

Query: 1723 IIIRKPNIERNFPCEFCPAKFSRRDELKRHEKIHSGEKPLSCPYCDKCFMRSDHRTTHIRTHTGEKPYSCDICS 1944
            I   K   E+   C  C   F++  +LKRH   H+GEKP  CP C KCF  +    TH  THTGEKP+ C  C 
Sbjct:  420 IHALKHTGEKTHQCPQCGKFFAQAGDLKRHALTHTGEKPHQCPQCGKCFALASSLKTHALTHTGEKPHRCPQCG 493

HSP 9 Score: 62.7734 bits (151), Expect = 4.098e-10
Identity = 37/101 (36.63%), Postives = 46/101 (45.54%), Query Frame = -3

Query: 1618 ERNFPCEFCPAKFSRRDELKRHEKIHSGEKPLSCPYCDKCFMRSDHRTTHIRTHTGEKPYSCDICSKRFARSDEKLRHKRIHLKEKSKKNITHEICLKLMS 1920
            E+   C  C   F+    LK H   H+GEKP  CP C KCF  +     H   HTGEK + C  C K FA++ +  RH   H  EK  +      C  L S
Sbjct:  372 EKPHQCPQCGKCFALASSLKTHALTHTGEKPHRCPQCGKCFALASSLNIHALKHTGEKTHQCPQCGKFFAQAGDLKRHALTHTGEKPHQCPQCGKCFALAS 472

HSP 10 Score: 51.2174 bits (121), Expect = 1.597e-6
Identity = 32/86 (37.21%), Postives = 39/86 (45.35%), Query Frame = -3

Query: 1663 ERNFPCEFCPAKFSRRDELKRHEKIHSGEKPLSCPYCDKCFMRSDHRTTHIRTHTGEKPYSCDICSKRFARSDEKLRHKRIHLKEK 1920
            E+   C  C   F+    L  H   H+GEK   CP C K F ++     H  THTGEKP+ C  C K FA +     H   H  EK
Sbjct:  400 EKPHRCPQCGKCFALASSLNIHALKHTGEKTHQCPQCGKFFAQAGDLKRHALTHTGEKPHQCPQCGKCFALASSLKTHALTHTGEK 485

[Close]

BLAST of early growth response-4 vs. Ensembl Medaka
Match: egr2b (early growth response 2 [Source:NCBI gene;Acc:101170128])

HSP 1 Score: 119.398 bits (298), Expect = 4.721e-28
Identity = 66/147 (44.90%), Postives = 86/147 (58.50%), Query Frame = -3

Query: 1654 INSVSAIQLSSPIEESSIYNRRSQRPPT----DNKTLRKQAHEEKAHKIIIRKPNIERNFPC--EFCPAKFSRRDELKRHEKIHSGEKPLSCPYCDKCFMRSDHRTTHIRTHTGEKPYSCDICSKRFARSDEKLRHKRIHLKEKSKK 2076
            +N++    L  P    S  +   QR P+     N  LR      K      + P  ER +PC  E C  +FSR DEL RH +IH+G KP  C  C + F RSDH TTHIRTHTGEKP++CD C ++FARSDE+ RH +IHL++K +K
Sbjct:  273 LNTIRNFTLGGPGAGGS--DAGQQRLPSAYSPQNLPLRPILRPRKYPNRPSKTPIHERPYPCPAEGCDRRFSRSDELTRHIRIHTGHKPFQCRICMRNFSRSDHLTTHIRTHTGEKPFACDFCGRKFARSDERKRHTKIHLRQKERK 417

[Close]

BLAST of early growth response-4 vs. Ensembl Medaka
Match: egr3 (early growth response 3 [Source:NCBI gene;Acc:100272164])

HSP 1 Score: 117.857 bits (294), Expect = 9.109e-28
Identity = 52/85 (61.18%), Postives = 64/85 (75.29%), Query Frame = -3

Query: 1654 PCEFCPAKFSRRDELKRHEKIHSGEKPLSCPYCDKCFMRSDHRTTHIRTHTGEKPYSCDICSKRFARSDEKLRHKRIHLKEKSKK 1908
            P E C  +FSR DEL RH +IH+G KP  C  C + F RSDH TTHIRTHTGEKP+SC+ C ++FARSDE+ RH ++HLK+K KK
Sbjct:  299 PAENCDRRFSRSDELTRHLRIHTGHKPFQCRICMRSFSRSDHLTTHIRTHTGEKPFSCEFCGRKFARSDERKRHAKVHLKQKDKK 383

HSP 2 Score: 55.8398 bits (133), Expect = 1.164e-7
Identity = 25/57 (43.86%), Postives = 32/57 (56.14%), Query Frame = -3

Query: 1747 RNFPCEFCPAKFSRRDELKRHEKIHSGEKPLSCPYCDKCFMRSDHRTTHIRTHTGEK 1917
            + F C  C   FSR D L  H + H+GEKP SC +C + F RSD R  H + H  +K
Sbjct:  324 KPFQCRICMRSFSRSDHLTTHIRTHTGEKPFSCEFCGRKFARSDERKRHAKVHLKQK 380

[Close]

BLAST of early growth response-4 vs. Ensembl Medaka
Match: egr1 (early growth response 1 [Source:NCBI gene;Acc:100272163])

HSP 1 Score: 119.013 bits (297), Expect = 1.168e-27
Identity = 55/96 (57.29%), Postives = 71/96 (73.96%), Query Frame = -3

Query: 1654 RKPNIERNF--PCEFCPAKFSRRDELKRHEKIHSGEKPLSCPYCDKCFMRSDHRTTHIRTHTGEKPYSCDICSKRFARSDEKLRHKRIHLKEKSKK 1935
            + P  ER +  P E C  +FSR DEL RH +IH+G+KP  C  C + F RSDH TTHIRTHTGEKP++C+IC ++FARSDE+ RH +IHL++K KK
Sbjct:  305 KTPPHERPYACPVETCDRRFSRSDELTRHIRIHTGQKPFQCRICMRNFSRSDHLTTHIRTHTGEKPFACEICGRKFARSDERKRHTKIHLRQKDKK 400

[Close]

BLAST of early growth response-4 vs. Ensembl Medaka
Match: ENSORLT00000034291.1 (early growth response protein 2b [Source:NCBI gene;Acc:101164744])

HSP 1 Score: 116.701 bits (291), Expect = 1.552e-27
Identity = 55/96 (57.29%), Postives = 69/96 (71.88%), Query Frame = -3

Query: 1654 RKPNIERNFPC--EFCPAKFSRRDELKRHEKIHSGEKPLSCPYCDKCFMRSDHRTTHIRTHTGEKPYSCDICSKRFARSDEKLRHKRIHLKEKSKK 1935
            + P  +R +PC  E C  +FSR DEL RH +IH+G KP  C  C + F RSDH TTHIRTHTGEKP+SC  C ++FARSDE+ RH +IHL++K KK
Sbjct:  296 KTPVHQRPYPCPAESCDRRFSRSDELSRHLRIHTGHKPFQCRICMRNFSRSDHLTTHIRTHTGEKPFSCQQCGRKFARSDERRRHMKIHLRQKEKK 391

[Close]

BLAST of early growth response-4 vs. Ensembl Medaka
Match: ENSORLT00000000940.2 (early growth response protein 1 [Source:NCBI gene;Acc:101160576])

HSP 1 Score: 108.612 bits (270), Expect = 1.909e-24
Identity = 50/96 (52.08%), Postives = 66/96 (68.75%), Query Frame = -3

Query: 1654 RKPNIERNF--PCEFCPAKFSRRDELKRHEKIHSGEKPLSCPYCDKCFMRSDHRTTHIRTHTGEKPYSCDICSKRFARSDEKLRHKRIHLKEKSKK 1935
            R P  ER    P + C  +FSR DEL RH ++H+G+KP  C  C + F RSDH TTHIRTHTGEKP+ C  C ++FARSDE+ RH +IH +++ +K
Sbjct:  275 RTPPHERPHVCPADGCERRFSRSDELTRHVRVHTGQKPFQCRICMRSFSRSDHLTTHIRTHTGEKPFPCSECGRKFARSDERKRHAKIHQRQRDRK 370

[Close]

BLAST of early growth response-4 vs. Planmine SMEST
Match: SMESG000028801.1 (SMESG000028801.1)

HSP 1 Score: 585.874 bits (1509), Expect = 0.000e+0
Identity = 329/350 (94.00%), Postives = 329/350 (94.00%), Query Frame = -3

Query: 1531 MQPCFINEIVTKIDSFIFLYCTSFLMLLFEKFSESDFDSIETGYTPTGKFGTFFKDTSNVDNLDTPQPLXXXXXXXXXXXXNYLISENRLKKCVDIHDRISNRIRQLXXXXXXXXXXXXXXXXXXSVEYKISRGFGNILLDEGQKNTLNTNSGTSLYISINYKDIHPNINSVSAIQLSSPIEESSIYNRRSQRPPTDNKTLRKQAHEEKAHKIIIRKPNIERNFPCEFCPAKFSRRDELKRHEKIHSGEKPLSCPYCDKCFMRSDHRTTHIRTHTGEKPYSCDICSKRFARSDEKLRHKRIHLKEKSKKNITHEICLKLMSQANMENSNKIESKLFPHSSNTLIDLGLQI 2580
            MQPCFINEIVTKIDSFIFLYCTSFLMLLFEKFSESDFDSIETGYTPTGKFGTFFKDTSNVDNLDTPQPLEDNSFEFEDFSFNYLISENRLKKCVDIHDRISNRIRQLSCTSSISCSSSQSCDTTTSVEYKISRGFGNILLDEGQKNTLNTNS                     AIQLSSPIEESSIYNRRSQRPPTDNKTLRKQAHEEKAHKIIIRKPNIERNFPCEFCPAKFSRRDELKRHEKIHSGEKPLSCPYCDKCFMRSDHRTTHIRTHTGEKPYSCDICSKRFARSDEKLRHKRIHLKEKSKKNITHEICLKLMSQANMENSNKIESKLFPHSSNTLIDLGLQI
Sbjct:    1 MQPCFINEIVTKIDSFIFLYCTSFLMLLFEKFSESDFDSIETGYTPTGKFGTFFKDTSNVDNLDTPQPLEDNSFEFEDFSFNYLISENRLKKCVDIHDRISNRIRQLSCTSSISCSSSQSCDTTTSVEYKISRGFGNILLDEGQKNTLNTNS---------------------AIQLSSPIEESSIYNRRSQRPPTDNKTLRKQAHEEKAHKIIIRKPNIERNFPCEFCPAKFSRRDELKRHEKIHSGEKPLSCPYCDKCFMRSDHRTTHIRTHTGEKPYSCDICSKRFARSDEKLRHKRIHLKEKSKKNITHEICLKLMSQANMENSNKIESKLFPHSSNTLIDLGLQI 329

[Close]

BLAST of early growth response-4 vs. Planmine SMEST
Match: SMESG000028801.1 (SMESG000028801.1)

HSP 1 Score: 533.487 bits (1373), Expect = 0.000e+0
Identity = 304/325 (93.54%), Postives = 304/325 (93.54%), Query Frame = -3

Query: 1531 MLLFEKFSESDFDSIETGYTPTGKFGTFFKDTSNVDNLDTPQPLXXXXXXXXXXXXNYLISENRLKKCVDIHDRISNRIRQLXXXXXXXXXXXXXXXXXXSVEYKISRGFGNILLDEGQKNTLNTNSGTSLYISINYKDIHPNINSVSAIQLSSPIEESSIYNRRSQRPPTDNKTLRKQAHEEKAHKIIIRKPNIERNFPCEFCPAKFSRRDELKRHEKIHSGEKPLSCPYCDKCFMRSDHRTTHIRTHTGEKPYSCDICSKRFARSDEKLRHKRIHLKEKSKKNITHEICLKLMSQANMENSNKIESKLFPHSSNTLIDLGLQI 2505
            MLLFEKFSESDFDSIETGYTPTGKFGTFFKDTSNVDNLDTPQPLEDNSFEFEDFSFNYLISENRLKKCVDIHDRISNRIRQLSCTSSISCSSSQSCDTTTSVEYKISRGFGNILLDEGQKNTLNTNS                     AIQLSSPIEESSIYNRRSQRPPTDNKTLRKQAHEEKAHKIIIRKPNIERNFPCEFCPAKFSRRDELKRHEKIHSGEKPLSCPYCDKCFMRSDHRTTHIRTHTGEKPYSCDICSKRFARSDEKLRHKRIHLKEKSKKNITHEICLKLMSQANMENSNKIESKLFPHSSNTLIDLGLQI
Sbjct:    1 MLLFEKFSESDFDSIETGYTPTGKFGTFFKDTSNVDNLDTPQPLEDNSFEFEDFSFNYLISENRLKKCVDIHDRISNRIRQLSCTSSISCSSSQSCDTTTSVEYKISRGFGNILLDEGQKNTLNTNS---------------------AIQLSSPIEESSIYNRRSQRPPTDNKTLRKQAHEEKAHKIIIRKPNIERNFPCEFCPAKFSRRDELKRHEKIHSGEKPLSCPYCDKCFMRSDHRTTHIRTHTGEKPYSCDICSKRFARSDEKLRHKRIHLKEKSKKNITHEICLKLMSQANMENSNKIESKLFPHSSNTLIDLGLQI 304

[Close]

BLAST of early growth response-4 vs. Planmine SMEST
Match: SMESG000042500.1 (SMESG000042500.1)

HSP 1 Score: 152.91 bits (385), Expect = 1.342e-39
Identity = 70/97 (72.16%), Postives = 76/97 (78.35%), Query Frame = -3

Query: 1672 IIRKP-------NIERNFPCEFCPAKFSRRDELKRHEKIHSGEKPLSCPYCDKCFMRSDHRTTHIRTHTGEKPYSCDICSKRFARSDEKLRHKRIHL 1941
            II KP         E+ F C  C  KF+RRDEL+RHEKIHSGEKPLSCPYCDKCF+RSDHR THIRTHTGEKPY+CDIC KRFARSDEKLRH + H 
Sbjct:  251 IIDKPVKTKKVVQTEKTFCCSTCDVKFTRRDELRRHEKIHSGEKPLSCPYCDKCFIRSDHRKTHIRTHTGEKPYACDICLKRFARSDEKLRHTKTHF 347

[Close]

BLAST of early growth response-4 vs. Planmine SMEST
Match: SMESG000034285.1 (SMESG000034285.1)

HSP 1 Score: 136.732 bits (343), Expect = 1.761e-34
Identity = 67/130 (51.54%), Postives = 91/130 (70.00%), Query Frame = -3

Query: 1654 PIEESSIYNRRSQRPPTDNKTLRKQAHEEKAHKIIIRKPNIERNFPCEFCPAKFSRRDELKRHEKIHSGEKPLSCPYCDKCFMRSDHRTTHIRTHTGEKPYSCDICSKRFARSDEKLRHKRIHLKEKSKK 2043
            P++ S I N+ + +    +  +   + EEK+      +   +++F C  CP++F+R+DEL+RHEKIH+G K L CPYCDK F+RSDHR THIRTHTGEKPYSC+IC K FARSDE+ RH RIH K+  +K
Sbjct:  138 PLDSSQISNQTNIKLEALHDPISTISREEKSKSGKSNQLPPDKSFTCSNCPSRFTRKDELRRHEKIHTGIKTLCCPYCDKTFIRSDHRRTHIRTHTGEKPYSCEICCKCFARSDERTRHTRIHSKDPVRK 267

[Close]

BLAST of early growth response-4 vs. Planmine SMEST
Match: SMESG000000959.1 (SMESG000000959.1)

HSP 1 Score: 119.013 bits (297), Expect = 2.928e-30
Identity = 52/79 (65.82%), Postives = 62/79 (78.48%), Query Frame = -3

Query: 1681 RNFPCEFCPAKFSRRDELKRHEKIHSGEKPLSCPYCDKCFMRSDHRTTHIRTHTGEKPYSCDICSKRFARSDEKLRHKR 1917
            R F C  C   F RRDELKRHE+IH+GE+PL+C +CDK FMRSDH +TH R HTGEKPY C++CS+ F RSDE+LRH R
Sbjct:  115 RQFTCNTCKKAFYRRDELKRHERIHTGERPLACNFCDKRFMRSDHLSTHTRIHTGEKPYRCNVCSRLFGRSDERLRHFR 193

HSP 2 Score: 57.7658 bits (138), Expect = 3.972e-9
Identity = 29/75 (38.67%), Postives = 40/75 (53.33%), Query Frame = -3

Query: 1609 KPLSCPYCDKCFMRSDHRTTHIRTHTGEKPYSCDICSKRFARSDEKLRHKRIHLKEKSKKNITHEICLKLMSQAN 1833
            +  +C  C K F R D    H R HTGE+P +C+ C KRF RSD    H RIH  EK  +     +C +L  +++
Sbjct:  115 RQFTCNTCKKAFYRRDELKRHERIHTGERPLACNFCDKRFMRSDHLSTHTRIHTGEKPYRC---NVCSRLFGRSD 186

The following BLAST results are available for this feature:

BLAST of early growth response-4 vs. Ensembl Human
BLAST of early growth response-4 vs. Ensembl Celegans
BLAST of early growth response-4 vs. Ensembl Fly
BLAST of early growth response-4 vs. Ensembl Zebrafish
BLAST of early growth response-4 vs. Ensembl Xenopus
BLAST of early growth response-4 vs. Ensembl Mouse
BLAST of early growth response-4 vs. UniProt/SwissProt
BLAST of early growth response-4 vs. TrEMBL
BLAST of early growth response-4 vs. Ensembl Cavefish
BLAST of early growth response-4 vs. Ensembl Sea Lamprey
BLAST of early growth response-4 vs. Ensembl Yeast
BLAST of early growth response-4 vs. Ensembl Nematostella
BLAST of early growth response-4 vs. Ensembl Medaka
BLAST of early growth response-4 vs. Planmine SMEST

BLAST of early growth response-4 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
EGR1	2.361e-28	58.33	early growth response 1 [Source:HGNC Symbol;Acc:HG...	[more]
EGR3	2.553e-28	44.59	early growth response 3 [Source:HGNC Symbol;Acc:HG...	[more]
EGR3	2.793e-28	44.59	early growth response 3 [Source:HGNC Symbol;Acc:HG...	[more]
EGR2	5.556e-28	43.80	early growth response 2 [Source:HGNC Symbol;Acc:HG...	[more]
EGR2	6.533e-28	43.80	early growth response 2 [Source:HGNC Symbol;Acc:HG...	[more]

BLAST of early growth response-4 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5


Match Name	E-value	Identity	Description
egrh-2	2.759e-27	62.20	EGR (Early Growth factor Response factor) Homolog ...	[more]
egrh-2	5.551e-27	62.20	EGR (Early Growth factor Response factor) Homolog ...	[more]
egrh-2	7.462e-27	62.20	EGR (Early Growth factor Response factor) Homolog ...	[more]
egrh-2	1.402e-26	61.18	EGR (Early Growth factor Response factor) Homolog ...	[more]
egrh-1	1.601e-25	57.83	EGR (Early Growth factor Response factor) Homolog ...	[more]

BLAST of early growth response-4 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5


Match Name	E-value	Identity	Description
sr	9.325e-29	59.38	gene:FBgn0003499 transcript:FBtr0330050	[more]
sr	9.802e-29	59.38	gene:FBgn0003499 transcript:FBtr0083542	[more]
sr	1.190e-28	59.38	gene:FBgn0003499 transcript:FBtr0301615	[more]
sr	2.123e-28	59.38	gene:FBgn0003499 transcript:FBtr0344633	[more]
sr	2.123e-28	59.38	gene:FBgn0003499 transcript:FBtr0083543	[more]

BLAST of early growth response-4 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
egr2a	3.542e-30	45.27	early growth response 2a [Source:ZFIN;Acc:ZDB-GENE...	[more]
egr2a	3.542e-30	45.27	early growth response 2a [Source:ZFIN;Acc:ZDB-GENE...	[more]
egr4	1.172e-29	43.48	early growth response 4 [Source:ZFIN;Acc:ZDB-GENE-...	[more]
egr2a	2.219e-29	45.27	early growth response 2a [Source:ZFIN;Acc:ZDB-GENE...	[more]
egr2b	2.575e-28	44.22	early growth response 2b [Source:NCBI gene;Acc:301...	[more]

BLAST of early growth response-4 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5


Match Name	E-value	Identity	Description
egr1	7.784e-29	58.33	early growth response 1 [Source:NCBI gene;Acc:1000...	[more]
egr1	8.748e-29	58.33	early growth response 1 [Source:NCBI gene;Acc:1000...	[more]
tbl1x	1.999e-28	52.17	transducin beta like 1 X-linked [Source:Xenbase;Ac...	[more]
serpinb4	3.416e-27	45.80	serpin peptidase inhibitor, clade B (ovalbumin), m...	[more]
usp31	2.924e-26	60.71	ubiquitin specific peptidase 31 [Source:Xenbase;Ac...	[more]

BLAST of early growth response-4 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Egr1	1.562e-28	58.33	early growth response 1 [Source:MGI Symbol;Acc:MGI...	[more]
Egr1	1.562e-28	58.33	early growth response 1 [Source:MGI Symbol;Acc:MGI...	[more]
Egr3	1.604e-28	44.30	early growth response 3 [Source:MGI Symbol;Acc:MGI...	[more]
Egr3	1.657e-28	44.30	early growth response 3 [Source:MGI Symbol;Acc:MGI...	[more]
Egr2	1.481e-27	51.35	early growth response 2 [Source:MGI Symbol;Acc:MGI...	[more]

BLAST of early growth response-4 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|O73693\|EGR1_TAEGU	2.785e-28	62.96	Early growth response protein 1 (Fragment) OS=Taen...	[more]
sp\|O73692\|EGR1_COTJA	2.918e-28	62.96	Early growth response protein 1 (Fragment) OS=Cotu...	[more]
sp\|A4II20\|EGR1_XENTR	4.634e-28	58.33	Early growth response protein 1 OS=Xenopus tropica...	[more]
sp\|O73691\|EGR1_CHICK	4.635e-28	62.96	Early growth response protein 1 (Fragment) OS=Gall...	[more]
sp\|Q6GQH4\|EGR1A_XENLA	5.207e-28	58.33	Early growth response protein 1-A OS=Xenopus laevi...	[more]

BLAST of early growth response-4 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
I1ZI72	0.000e+0	99.38	Early growth response-4 OS=Schmidtea mediterranea ...	[more]
X1XEL1	1.440e-35	44.00	Uncharacterized protein OS=Acyrthosiphon pisum OX=...	[more]
H9CXV3	9.668e-31	51.54	EGR-1 OS=Schmidtea mediterranea OX=79327 PE=2 SV=1	[more]
A0A4Y1LSX9	5.655e-30	62.50	Early growth response 1 OS=Octopus vulgaris OX=664...	[more]
A0A0L8IBN0	7.414e-30	62.50	Uncharacterized protein OS=Octopus bimaculoides OX...	[more]

BLAST of early growth response-4 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
egr4	3.823e-28	55.43	early growth response protein 1-B [Source:NCBI gen...	[more]
egr2b	4.421e-28	56.70	early growth response 2 [Source:NCBI gene;Acc:1030...	[more]
egr4	7.832e-28	55.43	early growth response protein 1-B [Source:NCBI gen...	[more]
egr3	1.602e-27	61.18	early growth response 3 [Source:NCBI gene;Acc:1030...	[more]
EGR2	4.274e-27	53.13	early growth response protein 2b-like [Source:NCBI...	[more]

BLAST of early growth response-4 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5


Match Name	E-value	Identity	Description
egr4	1.657e-29	59.14	early growth response 4 [Source:ZFIN;Acc:ZDB-GENE-...	[more]
ENSPMAT00000007569.1	1.846e-19	46.51	pep scaffold:Pmarinus_7.0:GL477836:135382:139743:-...	[more]
wt1a	2.351e-19	36.71	WT1 transcription factor a [Source:ZFIN;Acc:ZDB-GE...	[more]
ENSPMAT00000000923.1	2.061e-18	39.53	pep scaffold:Pmarinus_7.0:GL480775:18221:19434:-1 ...	[more]
ENSPMAT00000005004.1	8.277e-18	45.68	pep scaffold:Pmarinus_7.0:GL484587:30140:35096:1 g...	[more]

BLAST of early growth response-4 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 5


Match Name	E-value	Identity	Description
AZF1	7.575e-15	45.68	Zinc-finger transcription factor; involved in diau...	[more]
MIG1	3.217e-14	54.39	Transcription factor involved in glucose repressio...	[more]
ZAP1	2.377e-13	45.12	Zinc-regulated transcription factor; binds to zinc...	[more]
CRZ1	2.389e-12	36.11	Transcription factor, activates transcription of s...	[more]
MIG3	1.874e-10	44.62	Transcriptional regulator; partially nonfunctional...	[more]

BLAST of early growth response-4 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5


Match Name	E-value	Identity	Description
EDO49112	6.123e-29	61.73	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO47692	3.840e-20	47.56	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO29702	2.302e-18	37.40	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO45259	4.788e-18	42.72	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO45483	8.187e-18	37.42	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of early growth response-4 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5


Match Name	E-value	Identity	Description
egr2b	4.721e-28	44.90	early growth response 2 [Source:NCBI gene;Acc:1011...	[more]
egr3	9.109e-28	61.18	early growth response 3 [Source:NCBI gene;Acc:1002...	[more]
egr1	1.168e-27	57.29	early growth response 1 [Source:NCBI gene;Acc:1002...	[more]
ENSORLT00000034291.1	1.552e-27	57.29	early growth response protein 2b [Source:NCBI gene...	[more]
ENSORLT00000000940.2	1.909e-24	52.08	early growth response protein 1 [Source:NCBI gene;...	[more]

BLAST of early growth response-4 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5


Match Name	E-value	Identity	Description
SMESG000028801.1	0.000e+0	94.00	SMESG000028801.1	[more]
SMESG000028801.1	0.000e+0	93.54	SMESG000028801.1	[more]
SMESG000042500.1	1.342e-39	72.16	SMESG000042500.1	[more]
SMESG000034285.1	1.761e-34	51.54	SMESG000034285.1	[more]
SMESG000000959.1	2.928e-30	65.82	SMESG000000959.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Cross References

External references for this transcript


Database	Accession
SmedGD GBrowse	SMED30028658
GenBank	AFJ24726.1

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence
protein sequence

transcript sequence

>SMED30028658 ID=SMED30028658|Name=early growth response-4|organism=Schmidtea mediterranea sexual|type=transcript|length=2783bp
TAAATTATTCGAGCATTTATATTCCAATATATTTAAAGGAGTGTAGCAGG
ATTCTTAAATATGATTTCTTTAAAACCTTATGCTTCGTATAAATCGGAAT
CGGATATATTTTTTTGGTAACCATCTACGAGCAAAATTTCCAAATCCATG
CAAATTTTTCGAAGGTCTTCATCAATCATTTCTGCTTTAAAATTATAAAT
GAAGTTAAAATTTGTACTGTGCTCCTGAATCAACGTAAACCTATCACTTG
ATGACACAATTGCTTGATCAAGGATGTTATTAAAAAAAATATTTTTAAAA
TTTTGTGCTGCATCATTGATTACTTCATCTGGGTGCTCATAGCTTTCTTC
TGCGACGATCTCTTATTTGCTCAAACTCTGGCTCAATTTCTAAATGTTGT
GCAATATTTTTGGCCTCTTCAATAACTTCATTAAACTTATCATCTGTTAT
GTACTTTTTTAAATAGTCAATATTATTAGAAAATATTGTTGTAGCTTCCG
AAACATTAAAATTTTCTTTCTGAAGTACTTTACGTGTAATATTTATTTGA
CTTAAAATATCATACCAGACAATCAGGCTGCAAATAAATTTAAAACATTC
CATTTTCCCCAAAATTGAAATTGCTTCAGATTTAATTTTGGCTGCTGTTT
GAGTTGTCACATTCGTTGCTTCATACAAAAATGCATTAAGAGCATTTATA
ATTTTTTTAATTGGAATCAAATCGAACGGCTTTAGTGCTTCAATGCGACA
GCTCATTTACATTTTTTAAAGATATCCCATCTTTGTGTAGAGGACGAGAA
AAAACGTTGTACAATATCGAAAAAAGTTACAGCTTCTATACAACAGCTTG
CTGCATCATTGACAGCTAATATTATAAGGACTTTTTTGATTTTCACCTCT
GATATCTTTTCATTTATAAATAACATATTTTCCACAAAATTTATAAAATC
AAGGTCGACACAATGAATATTACACACCTTTGGTATCAGGAATTTTAGCT
ATATTATTTTCAGGTGCACCATCATTCCTAACAAAGTTTTTATAATAGTT
TTGAAATATCCATTCAGCAAAACACCATGTTGCTTTTTTTTACAATGAGT
ACAGAGCCTTATGCAATCGATACAGCCGAAATTTCACTTTTAACGGGTTG
TTATACATCATCTCCATCACAGAAACCAAATATGTTTACGGCCAAAAGGC
GAAATAGTGATTTTCCGACTTGATTTACTTTTTCCTAAAAGCATTAATTT
TTTCACCGACATATAAAGATATGAAATTAATATAAACAAGAAACTAAATC
CTGGACGGTCGAATAGTGAAGCTCTTCTATCTCTATATCCAGATTAATGA
TTTATTTCTACATGCAATAATGAACAAAACTTCAACATTAACAAGAAACA
ATGCCCATGTAAAATCATTAAAAATAAATCTGTCAAAATAAAGTTGATTG
GCCATTAATCTTTCAAAATTCAGTTTATTGCGGGTATAAAAATAAAAATA
TAAAATGAAAATTTATCTTTTGAATTTTCAAATTTGTAGACCCAAATCAA
TCAACGTGTTGCTGGAATGAGGAAATAATTTAGATTCAATTTTATTACTA
TTTTCCATATTTGCCTGCGACATAAGTTTTAGACATATTTCGTGTGTGAT
ATTTTTCTTGGATTTTTCTTTTAAATGAATACGCTTGTGTCTTAATTTTT
CATCAGAACGGGCAAATCGCTTTGAGCAAATATCACAACTATACGGCTTT
TCTCCAGTATGTGTTCGAATGTGTGTTGTACGATGATCTGATCGCATAAA
ACATTTATCGCAATATGGACAAGAAAGTGGCTTTTCTCCACTATGAATTT
TTTCATGCCTTTTTAATTCATCTCTTCTAGAAAATTTAGCGGGACAGAAT
TCACAAGGAAAATTTCTCTCGATATTTGGTTTACGAATTATAATTTTATG
AGCCTTTTCTTCGTGTGCTTGTTTTCTTAAGGTTTTATTATCTGTTGGAG
GTCTTTGAGATCGTCTGTTATAAATGCTGGATTCTTCAATTGGTGATGAA
AGTTGTATTGCTGAAACAGAATTGATATTTGGATGAATATCTTTGTAGTT
AATTGATATATAAAGTGATGTACCTGAATTGGTATTTAAAGTATTTTTCT
GACCTTCATCTAATAAAATGTTACCAAACCCGCGAGAAATTTTATATTCG
ACACTAGTGGTAGTGTCGCATGATTGTGATGAACTACAACTTATAGAACT
CGTACATGATAATTGTCTTATGCGATTAGAAATTCTATCGTGAATATCTA
CACATTTTTTCAGACGATTTTCAGAAATCAAATAATTAAAACTGAAATCT
TCAAATTCAAAGGAATTATCTTCTAAAGGTTGTGGTGTGTCTAAATTATC
AACATTTGAAGTATCTTTAAAAAATGTACCAAATTTCCCAGTAGGAGTAT
ATCCAGTTTCAATTGAATCAAAATCACTTTCTGAAAATTTCTCAAACAAC
AACATTAAAAATGAAGTACAATAAAGGAAAATGAATGAATCAATTTTTGT
AACAATTTCATTTATAAAACATGGTTGCATAATTTTTTTCTTACCTTCTA
CGCCTAATTTAGTAAGTAATTGAAACTTAACCAATCAAAATCTAGGAAGG
AATCGTCATGTTATATTTTTGGTAACAATTTTCTCTAGCAGTAAAATGTA
AAATCTATAATATTTAGAAAATCTGTAATGGCAAATAACATTGTAAATTG
AAATTAGTTTTCAAACAGTGACATTTCAACATA

protein sequence of SMED30028658-orf-1

>SMED30028658-orf-1 ID=SMED30028658-orf-1|Name=SMED30028658-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=351bp
MQPCFINEIVTKIDSFIFLYCTSFLMLLFEKFSESDFDSIETGYTPTGKF
GTFFKDTSNVDNLDTPQPLEDNSFEFEDFSFNYLISENRLKKCVDIHDRI
SNRIRQLSCTSSISCSSSQSCDTTTSVEYKISRGFGNILLDEGQKNTLNT
NSGTSLYISINYKDIHPNINSVSAIQLSSPIEESSIYNRRSQRPPTDNKT
LRKQAHEEKAHKIIIRKPNIERNFPCEFCPAKFSRRDELKRHEKIHSGEK
PLSCPYCDKCFMRSDHRTTHIRTHTGEKPYSCDICSKRFARSDEKLRHKR
IHLKEKSKKNITHEICLKLMSQANMENSNKIESKLFPHSSNTLIDLGLQI
*

protein sequence of SMED30028658-orf-2

>SMED30028658-orf-2 ID=SMED30028658-orf-2|Name=SMED30028658-orf-2|organism=Schmidtea mediterranea sexual|type=polypeptide|length=140bp
MSCRIEALKPFDLIPIKKIINALNAFLYEATNVTTQTAAKIKSEAISILG
KMECFKFICSLIVWYDILSQINITRKVLQKENFNVSEATTIFSNNIDYLK
KYITDDKFNEVIEEAKNIAQHLEIEPEFEQIRDRRRRKL*

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000099	neuron
PLANA:0000101	muscle cell
PLANA:0000418	head

Vocabulary: **INTERPRO**
Term	Definition
IPR036236	Znf_C2H2_sf
IPR015880	Znf_C2H2-like
IPR013087	Znf_C2H2_type
IPR007087	Znf_C2H2

Vocabulary: **molecular function**
Term	Definition
GO:0003676	nucleic acid binding
GO:0046872	metal ion binding

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR013087	Zinc finger C2H2-type	SMART	SM00355	c2h2final6	coord: 280..302 e-value: 0.0067 score: 25.6 coord: 224..246 e-value: 6.7E-4 score: 29.0 coord: 252..274 e-value: 0.14 score: 21.3
IPR013087	Zinc finger C2H2-type	PFAM	PF00096	zf-C2H2	coord: 280..302 e-value: 0.0043 score: 17.4 coord: 253..274 e-value: 0.0014 score: 19.0
IPR013087	Zinc finger C2H2-type	PROSITE	PS00028	ZINC_FINGER_C2H2_1	coord: 254..274
IPR013087	Zinc finger C2H2-type	PROSITE	PS00028	ZINC_FINGER_C2H2_1	coord: 226..246
IPR013087	Zinc finger C2H2-type	PROSITE	PS00028	ZINC_FINGER_C2H2_1	coord: 282..302
IPR013087	Zinc finger C2H2-type	PROSITE	PS50157	ZINC_FINGER_C2H2_2	coord: 252..279 score: 14.295
IPR013087	Zinc finger C2H2-type	PROSITE	PS50157	ZINC_FINGER_C2H2_2	coord: 224..251 score: 15.293
IPR013087	Zinc finger C2H2-type	PROSITE	PS50157	ZINC_FINGER_C2H2_2	coord: 280..307 score: 12.674
None	No IPR available	PFAM	PF13894	zf-C2H2_4	coord: 224..246 e-value: 5.8E-4 score: 20.5
None	No IPR available	GENE3D	G3DSA:3.30.160.60		coord: 251..276 e-value: 1.0E-12 score: 49.3
None	No IPR available	GENE3D	G3DSA:3.30.160.60		coord: 222..250 e-value: 8.4E-10 score: 40.3
None	No IPR available	GENE3D	G3DSA:3.30.160.60		coord: 277..308 e-value: 2.6E-12 score: 48.2
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 195..209
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 185..209
None	No IPR available	PANTHER	PTHR23235	TRANSCRIPTION FACTOR SP3	coord: 225..334
None	No IPR available	PANTHER	PTHR23235:SF60	STRIPE, ISOFORM D	coord: 225..334
IPR036236	Zinc finger C2H2 superfamily	SUPERFAMILY	SSF57667	beta-beta-alpha zinc fingers	coord: 219..261
IPR036236	Zinc finger C2H2 superfamily	SUPERFAMILY	SSF57667	beta-beta-alpha zinc fingers	coord: 250..302