GTPase activator protein
Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30028597 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 8
Homology
BLAST of GTPase activator protein vs. Ensembl Human
Match: NWD1 (NACHT and WD repeat domain containing 1 [Source:HGNC Symbol;Acc:HGNC:27619]) HSP 1 Score: 97.4413 bits (241), Expect = 1.225e-23 Identity = 55/160 (34.38%), Postives = 88/160 (55.00%), Query Frame = 1 Query: 13 INFPLRVRIILTISN----------LTILDESKIINIPKLESNISLLIIQQCLNRNCRSLTDVQWDIVKKTIRKCNLPLLVKITFDEISNWSSYDILKTTLYETIEESIHNLLERIEISHGKILVMHALSYITASRTGISETELEDILSIDEIVLNDVYQ 462 +N P RV +IL+ + +LD + L N +IQ L R+L+ V D++ ++ +C P +++ F+E W+S+ + L T EE+ H L R+E +HG++LV H L YI +SR G+SE EL+D+LS+D+ VL DVY+ Sbjct: 456 LNCPPRVHLILSACSGALGVLDTLQRVLLDPEAYWEVKPLSGNQGQQMIQLLLAAARRTLSPVHTDLLWASLPECGNPGRLRLAFEEARKWASFTV-PVPLATTAEEATHQLCTRLEQTHGQLLVAHVLGYIVSSRHGLSEAELKDVLSLDDEVLQDVYR 614
BLAST of GTPase activator protein vs. Ensembl Human
Match: NWD1 (NACHT and WD repeat domain containing 1 [Source:HGNC Symbol;Acc:HGNC:27619]) HSP 1 Score: 97.4413 bits (241), Expect = 1.225e-23 Identity = 55/160 (34.38%), Postives = 88/160 (55.00%), Query Frame = 1 Query: 13 INFPLRVRIILTISN----------LTILDESKIINIPKLESNISLLIIQQCLNRNCRSLTDVQWDIVKKTIRKCNLPLLVKITFDEISNWSSYDILKTTLYETIEESIHNLLERIEISHGKILVMHALSYITASRTGISETELEDILSIDEIVLNDVYQ 462 +N P RV +IL+ + +LD + L N +IQ L R+L+ V D++ ++ +C P +++ F+E W+S+ + L T EE+ H L R+E +HG++LV H L YI +SR G+SE EL+D+LS+D+ VL DVY+ Sbjct: 456 LNCPPRVHLILSACSGALGVLDTLQRVLLDPEAYWEVKPLSGNQGQQMIQLLLAAARRTLSPVHTDLLWASLPECGNPGRLRLAFEEARKWASFTV-PVPLATTAEEATHQLCTRLEQTHGQLLVAHVLGYIVSSRHGLSEAELKDVLSLDDEVLQDVYR 614
BLAST of GTPase activator protein vs. Ensembl Human
Match: NWD1 (NACHT and WD repeat domain containing 1 [Source:HGNC Symbol;Acc:HGNC:27619]) HSP 1 Score: 97.4413 bits (241), Expect = 1.225e-23 Identity = 55/160 (34.38%), Postives = 88/160 (55.00%), Query Frame = 1 Query: 13 INFPLRVRIILTISN----------LTILDESKIINIPKLESNISLLIIQQCLNRNCRSLTDVQWDIVKKTIRKCNLPLLVKITFDEISNWSSYDILKTTLYETIEESIHNLLERIEISHGKILVMHALSYITASRTGISETELEDILSIDEIVLNDVYQ 462 +N P RV +IL+ + +LD + L N +IQ L R+L+ V D++ ++ +C P +++ F+E W+S+ + L T EE+ H L R+E +HG++LV H L YI +SR G+SE EL+D+LS+D+ VL DVY+ Sbjct: 456 LNCPPRVHLILSACSGALGVLDTLQRVLLDPEAYWEVKPLSGNQGQQMIQLLLAAARRTLSPVHTDLLWASLPECGNPGRLRLAFEEARKWASFTV-PVPLATTAEEATHQLCTRLEQTHGQLLVAHVLGYIVSSRHGLSEAELKDVLSLDDEVLQDVYR 614
BLAST of GTPase activator protein vs. Ensembl Human
Match: NWD1 (NACHT and WD repeat domain containing 1 [Source:HGNC Symbol;Acc:HGNC:27619]) HSP 1 Score: 97.4413 bits (241), Expect = 1.230e-23 Identity = 55/160 (34.38%), Postives = 88/160 (55.00%), Query Frame = 1 Query: 13 INFPLRVRIILTISN----------LTILDESKIINIPKLESNISLLIIQQCLNRNCRSLTDVQWDIVKKTIRKCNLPLLVKITFDEISNWSSYDILKTTLYETIEESIHNLLERIEISHGKILVMHALSYITASRTGISETELEDILSIDEIVLNDVYQ 462 +N P RV +IL+ + +LD + L N +IQ L R+L+ V D++ ++ +C P +++ F+E W+S+ + L T EE+ H L R+E +HG++LV H L YI +SR G+SE EL+D+LS+D+ VL DVY+ Sbjct: 456 LNCPPRVHLILSACSGALGVLDTLQRVLLDPEAYWEVKPLSGNQGQQMIQLLLAAARRTLSPVHTDLLWASLPECGNPGRLRLAFEEARKWASFTV-PVPLATTAEEATHQLCTRLEQTHGQLLVAHVLGYIVSSRHGLSEAELKDVLSLDDEVLQDVYR 614
BLAST of GTPase activator protein vs. Ensembl Human
Match: NWD1 (NACHT and WD repeat domain containing 1 [Source:HGNC Symbol;Acc:HGNC:27619]) HSP 1 Score: 97.4413 bits (241), Expect = 1.232e-23 Identity = 55/160 (34.38%), Postives = 88/160 (55.00%), Query Frame = 1 Query: 13 INFPLRVRIILTISN----------LTILDESKIINIPKLESNISLLIIQQCLNRNCRSLTDVQWDIVKKTIRKCNLPLLVKITFDEISNWSSYDILKTTLYETIEESIHNLLERIEISHGKILVMHALSYITASRTGISETELEDILSIDEIVLNDVYQ 462 +N P RV +IL+ + +LD + L N +IQ L R+L+ V D++ ++ +C P +++ F+E W+S+ + L T EE+ H L R+E +HG++LV H L YI +SR G+SE EL+D+LS+D+ VL DVY+ Sbjct: 456 LNCPPRVHLILSACSGALGVLDTLQRVLLDPEAYWEVKPLSGNQGQQMIQLLLAAARRTLSPVHTDLLWASLPECGNPGRLRLAFEEARKWASFTV-PVPLATTAEEATHQLCTRLEQTHGQLLVAHVLGYIVSSRHGLSEAELKDVLSLDDEVLQDVYR 614
BLAST of GTPase activator protein vs. Ensembl Celegans
Match: T05C3.2 (pep chromosome:WBcel235:V:5493747:5503010:1 gene:WBGene00020254.1 transcript:T05C3.2.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:T05C3.2) HSP 1 Score: 127.872 bits (320), Expect = 1.116e-34 Identity = 56/136 (41.18%), Postives = 96/136 (70.59%), Query Frame = 1 Query: 64 ILDESKIINIPKLESNISLLIIQQCLNRNCRSLTDVQWDIVKKTIRKCNLPLLVKITFDEISNWSSYDILKTT-LYETIEESIHNLLERIEISHGKILVMHALSYITASRTGISETELEDILSIDEIVLNDVYQYH 468 I D+ + + +P L ++ ++++ L+ R+L++ QW+ V K + KC LPL VK+ + ++ W SY + T L+ +++ESI+ L R E HGK+LV HALSYI+A+R+GIS++E+ED++S+D+ VL+D++QYH Sbjct: 605 IEDKRQYLMVPSLGKDLGFQVVREWLSDKGRTLSERQWNTVSKALDKCTLPLFVKLIYATVARWKSYSRPQETILFSSLQESINVLFHRTESQHGKLLVSHALSYISAARSGISDSEVEDLISLDDKVLDDIFQYH 740
BLAST of GTPase activator protein vs. Ensembl Fly
Match: CG10185 (gene:FBgn0038397 transcript:FBtr0083235) HSP 1 Score: 130.568 bits (327), Expect = 1.851e-35 Identity = 62/133 (46.62%), Postives = 90/133 (67.67%), Query Frame = 1 Query: 73 ESKIINIPKLESNISLLIIQQCLNRNCRSLTDVQWDIVKKTIRKCNLPLLVKITFDEISNWSSYDILKTT-LYETIEESIHNLLERIEISHGKILVMHALSYITASRTGISETELEDILSIDEIVLNDVYQYH 468 E I + L ++++ +I+ + CR L + QW +V I KC+LP+ VK+ F EI W SY + T L T+ +SI L ER+E HG+ILV HAL+YITAS++G+SE+ELED++S+D+ VL+DVYQYH Sbjct: 537 EENFIEVTALGEDLAMNVIKMWMKTACRDLNNYQWRLVANAISKCSLPIFVKLVFAEICRWRSYTRPQETHLANTVMDSIMLLFERVEKQHGRILVFHALAYITASKSGLSESELEDLISLDDKVLDDVYQYH 669
BLAST of GTPase activator protein vs. Ensembl Zebrafish
Match: nwd1 (NACHT and WD repeat domain containing 1 [Source:ZFIN;Acc:ZDB-GENE-071116-8]) HSP 1 Score: 82.8037 bits (203), Expect = 9.141e-19 Identity = 56/156 (35.90%), Postives = 87/156 (55.77%), Query Frame = 1 Query: 22 PLRVRIILTISNLTILDESKII-----NIPKLE---SNISLLIIQQCLNRNCRSLTDVQWDIVKKTIRKCNLPLLVKITFDEISNWSSYDILKTT-LYETIEESIHNLLERIEISHGKILVMHALSYITASRTGISETELEDILSIDEIVLNDVYQ 462 P V+I+ + SN LD+ K + NI KLE + +I ++ R LT Q D + + + PL +K+ D WSSY + + L ++ EE + +E +E++HGK LV HALS+I SR G+SE EL+D+LS+D VL ++Y+ Sbjct: 518 PPNVQIVFSTSN-ECLDKCKSLVSAEENIFKLELLTKDQGRDVIDAYMSAAERKLTAEQQDAILRYFEQSGNPLHLKLMLDTAKLWSSYTPMSSVHLDKSAEEVMTQFVESLEVNHGKKLVSHALSFILLSRYGLSEAELQDVLSLDNDVLAEIYK 672
BLAST of GTPase activator protein vs. Ensembl Zebrafish
Match: nwd2 (NACHT and WD repeat domain containing 2 [Source:ZFIN;Acc:ZDB-GENE-161213-1]) HSP 1 Score: 78.9518 bits (193), Expect = 2.693e-17 Identity = 52/159 (32.70%), Postives = 81/159 (50.94%), Query Frame = 1 Query: 13 INFPLRVRIIL-TISN---------LTILDESKIINIPKLESNISLLIIQQCLNRNCRSLTDVQWDIVKKTIRKCNLPLLVKITFDEISNWSSY-DILKTTLYETIEESIHNLLERIEISHGKILVMHALSYITASRTGISETELEDILSIDEIVLNDV 456 ++ P VRI++ T+ N I DE + + + + ++Q L R +T Q V + + KC LP+ V + + E+ +W S+ D+ +L T+ ESI L +E G V AL YIT +R G++E ELEDILS+D VL D+ Sbjct: 535 VHLPRTVRIVVSTLPNKHGILQKLRCLIHDEEAYVELMQRDRKACSQTLKQQLLGVKRKVTSGQQIYVNEAMAKCTLPMFVNLIYREVVHWRSHKDVDDKSLCSTVHESIEQLFYSVENKLGSRFVFRALGYITMARAGLTELELEDILSLDNSVLGDI 693
BLAST of GTPase activator protein vs. Ensembl Zebrafish
Match: CU570791.3 (NACHT and WD repeat domain-containing protein 2-like [Source:NCBI gene;Acc:108179119]) HSP 1 Score: 65.0846 bits (157), Expect = 1.776e-12 Identity = 36/99 (36.36%), Postives = 59/99 (59.60%), Query Frame = 1 Query: 154 RSLTDVQWDIVKKTIRKCNLPLLVKITFDEISNW-SSYDILKTTLYETIEESIHNLLERIEISHGKILVMHALSYITASRTGISETELEDILSIDEIVL 447 R +T Q V + ++KC +PL V++ + + W S ++I + TL + SI + + +E HGK LV ALSY+T +R G++ EL D+LS D+ V+ Sbjct: 513 RKITSGQQVYVNEALKKCTVPLYVELLYRQAVCWHSEFEITEETLDLEVHNSIVLIFDHMERKHGKSLVSKALSYLTLARYGMTTAELTDVLSCDDEVV 611
BLAST of GTPase activator protein vs. Ensembl Zebrafish
Match: si:ch211-212k18.6 (si:ch211-212k18.6 [Source:ZFIN;Acc:ZDB-GENE-130530-938]) HSP 1 Score: 47.7506 bits (112), Expect = 1.616e-6 Identity = 33/130 (25.38%), Postives = 61/130 (46.92%), Query Frame = 1 Query: 82 IINIPKLESNISLLIIQQCLNRNCRSLTDVQWDIVKKTIRKCNLPLLVKITFDEISNWSSYDILKT-TLYETIEESIHNLLERIEISHGKILVMHALSYITASRTGISETELEDILSIDEIVLNDVYQYH 468 ++++P L + L+ + R LT+ QW ++ ++ C PL + + + E WSS+ + + + N+L +E +G LV I+ SR+GI+E EL +L D V ++ H Sbjct: 813 VLSLPALHHEEITSALASRLSSDSRQLTENQWTLLSQSCLSCPSPLYLNLAYAESKQWSSFTPENNLNIPKDPNQLFINVLVSLEREYGSCLVRRLALLISLSRSGIAEEELLVLLGCDGHVKREMASLH 942
BLAST of GTPase activator protein vs. Ensembl Xenopus
Match: ppp1r3c.1 (protein phosphatase 1, regulatory (inhibitor) subunit 3C, gene 1 [Source:Xenbase;Acc:XB-GENE-969181]) HSP 1 Score: 108.997 bits (271), Expect = 1.232e-27 Identity = 61/153 (39.87%), Postives = 91/153 (59.48%), Query Frame = 1 Query: 10 VINFPLRVRIILTISNLTILDESKIINIPKLESNISLLIIQQCLNRNCRSLTDVQWDIVKKTIRKCNLPLLVKITFDEISNWSSY-DILKTTLYETIEESIHNLLERIEISHGKILVMHALSYITASRTGISETELEDILSIDEIVLNDVYQY 465 V P I+ T+ + ++ D I + L + +I+ + R LT+ Q +IV + RKC PLL+K+ FDE WSSY I + + + +E++ L + +E HGK+LV HAL YI ASR+G+SE EL+DILS+D+ VL D+YQY Sbjct: 458 VSTLPEEGGILKTLKD-SVTDPECYIEVKPLSAEQGSQMIEMLMASAGRRLTNDQQEIVLGSFRKCGQPLLLKLAFDEAKRWSSYTPITELMIATSTKEAVSLLYQCLEQLHGKLLVSHALGYIVASRSGLSEAELKDILSLDDEVLADIYQY 609
BLAST of GTPase activator protein vs. Ensembl Xenopus
Match: hsp90ab1 (heat shock protein 90kDa alpha family class B member 1 [Source:Xenbase;Acc:XB-GENE-495311]) HSP 1 Score: 81.2629 bits (199), Expect = 5.461e-18 Identity = 57/160 (35.62%), Postives = 86/160 (53.75%), Query Frame = 1 Query: 13 INFPLRVRIILT--------ISNLTIL---DESKIINIPKLESNISLLIIQQCLNRNCRSLTDVQWDIVKKTIRKCNLPLLVKITFDEISNWSSY-DILKTTLYETIEESIHNLLERIEISHGKILVMHALSYITASRTGISETELEDILSIDEIVLNDV 456 ++ P VRII++ + L L ++S I IP+ + S ++ Q L R R +T Q V + KC LP+ V +TF E+ NW S+ D+ +TL T+ +I L +E G V AL YIT + TG+SE ELEDIL++D V+++V Sbjct: 532 VHLPRTVRIIISTLPNKHGILQKLRCLIHNEDSYIELIPRDKKMCSQILKHQLL-RVKRKVTSGQQIYVNEAFSKCTLPMFVNLTFREVRNWRSHKDVDGSTLCVTVHRNIEQLFWSLENKCGPRFVSRALGYITMATTGLSEVELEDILALDNTVMSEV 690
BLAST of GTPase activator protein vs. Ensembl Xenopus
Match: ENSXETT00000022477.1 (pep primary_assembly:Xenopus_tropicalis_v9.1:KV460486.1:142089:157740:1 gene:ENSXETG00000010819.1 transcript:ENSXETT00000022477.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 65.4698 bits (158), Expect = 1.466e-12 Identity = 38/113 (33.63%), Postives = 63/113 (55.75%), Query Frame = 1 Query: 127 IQQCLNRNCRSLTDVQWDIVKKTIRKCNLPLLVKITFDEISNWSSY-DILKTTLYETIEESIHNLLERIEISHGKILVMHALSYITASRTGISETELEDILSIDEIVLNDVYQ 462 ++ CL R +T Q V +++ PL V + F ++ W S+ D+ TL E E+ L ++EI +G+ +V LSYIT S++GI TEL D+L+ D++VL ++ Sbjct: 513 LKHCLLGCYRKITSGQQMYVNRSLETNTSPLQVHLLFKLVAEWKSHQDVDNQTLGEDTYEAAERLFHKLEIKYGREIVSRTLSYITLSQSGIGVTELVDLLTADDLVLEKFHE 625
BLAST of GTPase activator protein vs. Ensembl Xenopus
Match: ENSXETT00000003639.1 (uncharacterized LOC101730828 [Source:NCBI gene;Acc:101730828]) HSP 1 Score: 50.447 bits (119), Expect = 2.319e-7 Identity = 45/145 (31.03%), Postives = 76/145 (52.41%), Query Frame = 1 Query: 46 TISNLTILDESKIINIPKLESNISLLIIQQCLNRNCRSLTDVQWDIVKKTIRKCNLPLLVKITFDEISNWSSYDILKTTLYETIEESIHNL----LERIEISHGKILVMHALSYITASRTGISETELEDILSIDEIVLNDVYQYH 468 T+ LT+ + + IP L+S +I+ + R+ R LT Q ++ C LPL V ++ E W+SY + ++ ++H L L R+E SHG+ ++ SYI+ S+ G++ EL D+LS+D V+ +V QY Sbjct: 157 TLQKLTM--QQNVHQIPPLDSEEIRNMIEVWMERDNRRLTGRQKKVLFDACAACPLPLYVVSSYMESCLWTSYSSESDSY---LQPNLHKLYSAVLGRLEKSHGEQVMKMVASYISLSKNGVTLEELLDLLSLDLGVMQEVKQYQ 296
BLAST of GTPase activator protein vs. Ensembl Mouse
Match: Nwd1 (NACHT and WD repeat domain containing 1 [Source:MGI Symbol;Acc:MGI:2442268]) HSP 1 Score: 89.7373 bits (221), Expect = 4.480e-21 Identity = 55/156 (35.26%), Postives = 85/156 (54.49%), Query Frame = 1 Query: 22 PLRVRIILT-------ISNL--TILDESKIINIPKLESNISLLIIQQCLNRNCRSLTDVQWDIVKKTIRKCNLPLLVKITFDEISNWSSYDILKTTLYETIEESIHNLLERIEISHGKILVMHALSYITASRTGISETELEDILSIDEIVLNDVYQ 462 P RV +IL+ + NL T+ D S + L + IQ L R L+ Q D++ ++ +C P +++ F+E W+S+ + L T EE+ H L R+E +HG +LV H L YI +SR G+SE EL+D+LS+D+ VL VY+ Sbjct: 460 PPRVHLILSTCSGQQVLHNLQQTLKDPSTYWEVKALSGSQGQEFIQLLLAAEKRMLSPGQRDVLWASLPECGHPGRLRLAFEEARKWASFTV-PVPLATTAEEATHQLCIRLEETHGALLVAHVLGYIVSSRYGLSEAELKDVLSLDDEVLQAVYR 614
BLAST of GTPase activator protein vs. Ensembl Mouse
Match: Nwd1 (NACHT and WD repeat domain containing 1 [Source:MGI Symbol;Acc:MGI:2442268]) HSP 1 Score: 89.7373 bits (221), Expect = 4.488e-21 Identity = 55/156 (35.26%), Postives = 85/156 (54.49%), Query Frame = 1 Query: 22 PLRVRIILT-------ISNL--TILDESKIINIPKLESNISLLIIQQCLNRNCRSLTDVQWDIVKKTIRKCNLPLLVKITFDEISNWSSYDILKTTLYETIEESIHNLLERIEISHGKILVMHALSYITASRTGISETELEDILSIDEIVLNDVYQ 462 P RV +IL+ + NL T+ D S + L + IQ L R L+ Q D++ ++ +C P +++ F+E W+S+ + L T EE+ H L R+E +HG +LV H L YI +SR G+SE EL+D+LS+D+ VL VY+ Sbjct: 501 PPRVHLILSTCSGQQVLHNLQQTLKDPSTYWEVKALSGSQGQEFIQLLLAAEKRMLSPGQRDVLWASLPECGHPGRLRLAFEEARKWASFTV-PVPLATTAEEATHQLCIRLEETHGALLVAHVLGYIVSSRYGLSEAELKDVLSLDDEVLQAVYR 655
BLAST of GTPase activator protein vs. Ensembl Mouse
Match: Nwd1 (NACHT and WD repeat domain containing 1 [Source:MGI Symbol;Acc:MGI:2442268]) HSP 1 Score: 89.7373 bits (221), Expect = 4.488e-21 Identity = 55/156 (35.26%), Postives = 85/156 (54.49%), Query Frame = 1 Query: 22 PLRVRIILT-------ISNL--TILDESKIINIPKLESNISLLIIQQCLNRNCRSLTDVQWDIVKKTIRKCNLPLLVKITFDEISNWSSYDILKTTLYETIEESIHNLLERIEISHGKILVMHALSYITASRTGISETELEDILSIDEIVLNDVYQ 462 P RV +IL+ + NL T+ D S + L + IQ L R L+ Q D++ ++ +C P +++ F+E W+S+ + L T EE+ H L R+E +HG +LV H L YI +SR G+SE EL+D+LS+D+ VL VY+ Sbjct: 460 PPRVHLILSTCSGQQVLHNLQQTLKDPSTYWEVKALSGSQGQEFIQLLLAAEKRMLSPGQRDVLWASLPECGHPGRLRLAFEEARKWASFTV-PVPLATTAEEATHQLCIRLEETHGALLVAHVLGYIVSSRYGLSEAELKDVLSLDDEVLQAVYR 614
BLAST of GTPase activator protein vs. Ensembl Mouse
Match: Nwd2 (NACHT and WD repeat domain containing 2 [Source:MGI Symbol;Acc:MGI:1920464]) HSP 1 Score: 80.8777 bits (198), Expect = 5.368e-18 Identity = 47/123 (38.21%), Postives = 72/123 (58.54%), Query Frame = 1 Query: 91 IPKLESNISLLIIQQCLNRNCRSLTDVQWDIVKKTIRKCNLPLLVKITFDEISNWSSY-DILKTTLYETIEESIHNLLERIEISHGKILVMHALSYITASRTGISETELEDILSIDEIVLNDV 456 IP+ S ++ Q L R R +T Q V KC LP+ V +TF E+ +W S+ D+ +++L T+ ESI L +E G+ LV AL YIT ++ G+SE ELED+L++D V+N++ Sbjct: 570 IPRDRKMCSQVLKHQLL-RVKRKVTSGQQIYVNNAFSKCTLPMFVNLTFREVRHWRSHKDVDESSLCVTVHESIEQLFWSLEKKCGQKLVSRALGYITMAKMGLSEMELEDVLALDNSVMNEL 691
BLAST of GTPase activator protein vs. UniProt/SwissProt
Match: sp|Q149M9|NWD1_HUMAN (NACHT domain- and WD repeat-containing protein 1 OS=Homo sapiens OX=9606 GN=NWD1 PE=1 SV=3) HSP 1 Score: 97.4413 bits (241), Expect = 5.918e-23 Identity = 55/160 (34.38%), Postives = 88/160 (55.00%), Query Frame = 1 Query: 13 INFPLRVRIILTISN----------LTILDESKIINIPKLESNISLLIIQQCLNRNCRSLTDVQWDIVKKTIRKCNLPLLVKITFDEISNWSSYDILKTTLYETIEESIHNLLERIEISHGKILVMHALSYITASRTGISETELEDILSIDEIVLNDVYQ 462 +N P RV +IL+ + +LD + L N +IQ L R+L+ V D++ ++ +C P +++ F+E W+S+ + L T EE+ H L R+E +HG++LV H L YI +SR G+SE EL+D+LS+D+ VL DVY+ Sbjct: 456 LNCPPRVHLILSACSGALGVLDTLQRVLLDPEAYWEVKPLSGNQGQQMIQLLLAAARRTLSPVHTDLLWASLPECGNPGRLRLAFEEARKWASFTV-PVPLATTAEEATHQLCTRLEQTHGQLLVAHVLGYIVSSRHGLSEAELKDVLSLDDEVLQDVYR 614
BLAST of GTPase activator protein vs. UniProt/SwissProt
Match: sp|A6H603|NWD1_MOUSE (NACHT domain- and WD repeat-containing protein 1 OS=Mus musculus OX=10090 GN=Nwd1 PE=2 SV=2) HSP 1 Score: 89.7373 bits (221), Expect = 3.139e-20 Identity = 55/156 (35.26%), Postives = 85/156 (54.49%), Query Frame = 1 Query: 22 PLRVRIILT-------ISNL--TILDESKIINIPKLESNISLLIIQQCLNRNCRSLTDVQWDIVKKTIRKCNLPLLVKITFDEISNWSSYDILKTTLYETIEESIHNLLERIEISHGKILVMHALSYITASRTGISETELEDILSIDEIVLNDVYQ 462 P RV +IL+ + NL T+ D S + L + IQ L R L+ Q D++ ++ +C P +++ F+E W+S+ + L T EE+ H L R+E +HG +LV H L YI +SR G+SE EL+D+LS+D+ VL VY+ Sbjct: 460 PPRVHLILSTCSGQQVLHNLQQTLKDPSTYWEVKALSGSQGQEFIQLLLAAEKRMLSPGQRDVLWASLPECGHPGRLRLAFEEARKWASFTV-PVPLATTAEEATHQLCIRLEETHGALLVAHVLGYIVSSRYGLSEAELKDVLSLDDEVLQAVYR 614
BLAST of GTPase activator protein vs. UniProt/SwissProt
Match: sp|Q6P5U7|NWD2_MOUSE (NACHT and WD repeat domain-containing protein 2 OS=Mus musculus OX=10090 GN=Nwd2 PE=1 SV=2) HSP 1 Score: 80.8777 bits (198), Expect = 3.755e-17 Identity = 47/123 (38.21%), Postives = 72/123 (58.54%), Query Frame = 1 Query: 91 IPKLESNISLLIIQQCLNRNCRSLTDVQWDIVKKTIRKCNLPLLVKITFDEISNWSSY-DILKTTLYETIEESIHNLLERIEISHGKILVMHALSYITASRTGISETELEDILSIDEIVLNDV 456 IP+ S ++ Q L R R +T Q V KC LP+ V +TF E+ +W S+ D+ +++L T+ ESI L +E G+ LV AL YIT ++ G+SE ELED+L++D V+N++ Sbjct: 570 IPRDRKMCSQVLKHQLL-RVKRKVTSGQQIYVNNAFSKCTLPMFVNLTFREVRHWRSHKDVDESSLCVTVHESIEQLFWSLEKKCGQKLVSRALGYITMAKMGLSEMELEDVLALDNSVMNEL 691
BLAST of GTPase activator protein vs. UniProt/SwissProt
Match: sp|Q9ULI1|NWD2_HUMAN (NACHT and WD repeat domain-containing protein 2 OS=Homo sapiens OX=9606 GN=NWD2 PE=2 SV=3) HSP 1 Score: 79.337 bits (194), Expect = 1.207e-16 Identity = 46/123 (37.40%), Postives = 73/123 (59.35%), Query Frame = 1 Query: 91 IPKLESNISLLIIQQCLNRNCRSLTDVQWDIVKKTIRKCNLPLLVKITFDEISNWSSY-DILKTTLYETIEESIHNLLERIEISHGKILVMHALSYITASRTGISETELEDILSIDEIVLNDV 456 IP+ S ++ Q L R R +T Q V + KC LP+ V +TF E+ +W S+ D+ +++L T+ ESI L +E G+ LV AL YIT ++ G+SE ELED+L++D V++++ Sbjct: 570 IPRDRKMCSQVLKHQLL-RVKRKVTSGQQIYVNNALSKCTLPMFVNLTFREVRHWRSHKDVDESSLSVTVHESIEQLFWSLEKKCGQKLVSRALGYITMAKMGLSEMELEDVLALDNSVMSEL 691
BLAST of GTPase activator protein vs. TrEMBL
Match: R7U0H5 (Uncharacterized protein (Fragment) OS=Capitella teleta OX=283909 GN=CAPTEDRAFT_120102 PE=4 SV=1) HSP 1 Score: 147.517 bits (371), Expect = 2.094e-41 Identity = 72/136 (52.94%), Postives = 94/136 (69.12%), Query Frame = 1 Query: 64 ILDESKIINIPKLESNISLLIIQQCLNRNCRSLTDVQWDIVKKTIRKCNLPLLVKITFDEISNWSSYDILK-TTLYETIEESIHNLLERIEISHGKILVMHALSYITASRTGISETELEDILSIDEIVLNDVYQYH 468 I E + I L N+ I++ L+R R+++D QW +V + I KCNLPL VK+ FDEIS W SY +K TTL +I SI+ L +RIE+ HGK+LV AL YITA++ G+SE ELED+LS+DE VLNDVYQYH Sbjct: 12 ITAEKNFVEITPLGRNLGSTILKSWLDRANRTVSDEQWGVVTEAIEKCNLPLYVKLVFDEISQWRSYSSVKATTLAHSIHASINKLFDRIEMQHGKVLVARALGYITAAKGGLSEAELEDLLSLDEKVLNDVYQYH 147
BLAST of GTPase activator protein vs. TrEMBL
Match: R7TPK7 (Uncharacterized protein OS=Capitella teleta OX=283909 GN=CAPTEDRAFT_169319 PE=4 SV=1) HSP 1 Score: 147.132 bits (370), Expect = 7.262e-38 Identity = 72/136 (52.94%), Postives = 94/136 (69.12%), Query Frame = 1 Query: 64 ILDESKIINIPKLESNISLLIIQQCLNRNCRSLTDVQWDIVKKTIRKCNLPLLVKITFDEISNWSSYDILK-TTLYETIEESIHNLLERIEISHGKILVMHALSYITASRTGISETELEDILSIDEIVLNDVYQYH 468 I E + I L N+ I++ L+R R+++D QW +V + I KCNLPL VK+ FDEIS W SY +K TTL +I SI+ L +RIE+ HGK+LV AL YITA++ G+SE ELED+LS+DE VLNDVYQYH Sbjct: 540 ITAEKNFVEITPLGRNLGSTILKSWLDRANRTVSDEQWGVVTEAIEKCNLPLYVKLVFDEISQWRSYSSVKATTLAHSIHASINKLFDRIEMQHGKVLVARALGYITAAKGGLSEAELEDLLSLDEKVLNDVYQYH 675
BLAST of GTPase activator protein vs. TrEMBL
Match: A0A210PU69 (Uncharacterized protein OS=Mizuhopecten yessoensis OX=6573 GN=KP79_PYT19717 PE=4 SV=1) HSP 1 Score: 145.206 bits (365), Expect = 3.803e-37 Identity = 75/150 (50.00%), Postives = 100/150 (66.67%), Query Frame = 1 Query: 22 PLRVRIILTISNLTILDESKIINIPKLESNISLLIIQQCLNRNCRSLTDVQWDIVKKTIRKCNLPLLVKITFDEISNWSSYDILKTTLYE-TIEESIHNLLERIEISHGKILVMHALSYITASRTGISETELEDILSIDEIVLNDVYQYH 468 P I+ TI + DE+ + +P L N+S I++ L +++TD QWD+V + KCNLPL+VK+ FD+I W SY TT+ + TI +SI L ERIEI HGK LV HA YITA ++G+SE+ELED+LS+DE VLNDVYQYH Sbjct: 538 PRLYGILDTIRIMIEPDENYVAVLP-LGENLSGTILKFWLKNGNKAITDAQWDLVNEAFTKCNLPLMVKLVFDQICTWKSYTKPSTTVLQFTIHDSIMKLYERIEIQHGKTLVAHAFGYITAGKSGVSESELEDLLSLDEKVLNDVYQYH 686
BLAST of GTPase activator protein vs. TrEMBL
Match: A0A1S3KFF1 (NACHT and WD repeat domain-containing protein 2 OS=Lingula unguis OX=7574 GN=LOC106181362 PE=4 SV=1) HSP 1 Score: 143.665 bits (361), Expect = 1.314e-36 Identity = 82/163 (50.31%), Postives = 105/163 (64.42%), Query Frame = 1 Query: 13 INFPLRVRIIL-TISN-LTILD--------ESKIINIPKLESNISLLIIQQCLNRNCRSLTDVQWDIVKKTIRKCNLPLLVKITFDEISNWSSYDILK-TTLYETIEESIHNLLERIEISHGKILVMHALSYITASRTGISETELEDILSIDEIVLNDVYQYH 468 ++ P VRII+ T+ N +ILD E + I L ++ I++ L R RS+T+ QW IV + I KCNLPL VK+ DEI W SY + TTL TI ++I L +RIEI HGK LV HAL YITAS++G+SE ELED+LS+DE VLNDVYQYH Sbjct: 542 MSLPKNVRIIVSTLPNYFSILDTLKRMISEEGNFVIITPLGQDLGSAILRSWLGRANRSITEEQWKIVNEAISKCNLPLFVKLVCDEICRWKSYSKPQLTTLCYTIHDTIIKLFDRIEIQHGKTLVSHALGYITASKSGVSEAELEDLLSLDEKVLNDVYQYH 704
BLAST of GTPase activator protein vs. TrEMBL
Match: A0A2T7PBM5 (WD_REPEATS_REGION domain-containing protein OS=Pomacea canaliculata OX=400727 GN=C0Q70_10096 PE=4 SV=1) HSP 1 Score: 142.51 bits (358), Expect = 3.426e-36 Identity = 80/165 (48.48%), Postives = 101/165 (61.21%), Query Frame = 1 Query: 7 FVINFPLRVRIIL-TISNLTIL---------DESKIINIPKLESNISLLIIQQCLNRNCRSLTDVQWDIVKKTIRKCNLPLLVKITFDEISNWSSY-DILKTTLYETIEESIHNLLERIEISHGKILVMHALSYITASRTGISETELEDILSIDEIVLNDVYQYH 468 F ++ P V++I T+ N L DES I + L N+S IIQ L R++T QW IV + I KC+ PL VK+ FDEI W SY +T L TI E+I L ERIE+ HG+ LV HAL YITAS+ G+SE ELED+LS+D+ VLNDVYQYH Sbjct: 521 FPVHLPDCVKVIASTLPNYYALLDTLKFMIEDESNFIQVLPLGENLSSTIIQAWLKNENRAVTTEQWAIVNEAISKCSFPLFVKLVFDEICRWRSYTKPSQTVLAFTIHETILRLFERIELQHGRTLVAHALGYITASKDGVSEPELEDLLSLDDKVLNDVYQYH 685
BLAST of GTPase activator protein vs. Ensembl Cavefish
Match: nwd1 (NACHT and WD repeat domain containing 1 [Source:ZFIN;Acc:ZDB-GENE-071116-8]) HSP 1 Score: 88.9669 bits (219), Expect = 6.009e-21 Identity = 49/115 (42.61%), Postives = 69/115 (60.00%), Query Frame = 1 Query: 121 LIIQQCLNRNCRSLTDVQWDIVKKTIRKCNLPLLVKITFDEISNWSSYDILKTT-LYETIEESIHNLLERIEISHGKILVMHALSYITASRTGISETELEDILSIDEIVLNDVYQ 462 LI + +++ R LT Q D V ++ +K PL +K+ D W+SY L L +++E I L+ +E HGK+ V HAL YIT SR G+SE EL+DILS+D VL +VYQ Sbjct: 176 LITKAYMDKAGRRLTSEQVDAVLQSFQKTGSPLHLKLLLDMAKQWTSYTTLSDIRLGSSVQEVISLFLDSLEGKHGKLFVRHALGYITLSRFGLSEAELQDILSLDNDVLAEVYQ 290
BLAST of GTPase activator protein vs. Ensembl Cavefish
Match: nwd1 (NACHT and WD repeat domain containing 1 [Source:ZFIN;Acc:ZDB-GENE-071116-8]) HSP 1 Score: 88.9669 bits (219), Expect = 6.185e-21 Identity = 49/115 (42.61%), Postives = 69/115 (60.00%), Query Frame = 1 Query: 121 LIIQQCLNRNCRSLTDVQWDIVKKTIRKCNLPLLVKITFDEISNWSSYDILKTT-LYETIEESIHNLLERIEISHGKILVMHALSYITASRTGISETELEDILSIDEIVLNDVYQ 462 LI + +++ R LT Q D V ++ +K PL +K+ D W+SY L L +++E I L+ +E HGK+ V HAL YIT SR G+SE EL+DILS+D VL +VYQ Sbjct: 506 LITKAYMDKAGRRLTSEQVDAVLQSFQKTGSPLHLKLLLDMAKQWTSYTTLSDIRLGSSVQEVISLFLDSLEGKHGKLFVRHALGYITLSRFGLSEAELQDILSLDNDVLAEVYQ 620
BLAST of GTPase activator protein vs. Ensembl Cavefish
Match: nwd2 (NACHT and WD repeat domain containing 2 [Source:NCBI gene;Acc:103039682]) HSP 1 Score: 77.7962 bits (190), Expect = 4.843e-17 Identity = 41/102 (40.20%), Postives = 59/102 (57.84%), Query Frame = 1 Query: 154 RSLTDVQWDIVKKTIRKCNLPLLVKITFDEISNWSSY-DILKTTLYETIEESIHNLLERIEISHGKILVMHALSYITASRTGISETELEDILSIDEIVLNDV 456 R +T Q V + + KC LP+ V + + E+ +W S+ D+ +L T+ ESI L IE G V AL Y+T +R G++E ELEDILS+D VL D+ Sbjct: 582 RKVTSGQQIYVNEALAKCTLPMFVNLIYREVVHWRSHKDVDDKSLCSTVHESIEQLFFSIENKLGSRFVFRALGYVTMARAGLTEVELEDILSLDNSVLGDI 683
BLAST of GTPase activator protein vs. Ensembl Cavefish
Match: nwd2 (NACHT and WD repeat domain containing 2 [Source:NCBI gene;Acc:103039682]) HSP 1 Score: 77.7962 bits (190), Expect = 4.986e-17 Identity = 41/102 (40.20%), Postives = 59/102 (57.84%), Query Frame = 1 Query: 154 RSLTDVQWDIVKKTIRKCNLPLLVKITFDEISNWSSY-DILKTTLYETIEESIHNLLERIEISHGKILVMHALSYITASRTGISETELEDILSIDEIVLNDV 456 R +T Q V + + KC LP+ V + + E+ +W S+ D+ +L T+ ESI L IE G V AL Y+T +R G++E ELEDILS+D VL D+ Sbjct: 592 RKVTSGQQIYVNEALAKCTLPMFVNLIYREVVHWRSHKDVDDKSLCSTVHESIEQLFFSIENKLGSRFVFRALGYVTMARAGLTEVELEDILSLDNSVLGDI 693
BLAST of GTPase activator protein vs. Ensembl Cavefish
Match: nwd2 (NACHT and WD repeat domain containing 2 [Source:NCBI gene;Acc:103039682]) HSP 1 Score: 77.7962 bits (190), Expect = 5.096e-17 Identity = 41/102 (40.20%), Postives = 59/102 (57.84%), Query Frame = 1 Query: 154 RSLTDVQWDIVKKTIRKCNLPLLVKITFDEISNWSSY-DILKTTLYETIEESIHNLLERIEISHGKILVMHALSYITASRTGISETELEDILSIDEIVLNDV 456 R +T Q V + + KC LP+ V + + E+ +W S+ D+ +L T+ ESI L IE G V AL Y+T +R G++E ELEDILS+D VL D+ Sbjct: 669 RKVTSGQQIYVNEALAKCTLPMFVNLIYREVVHWRSHKDVDDKSLCSTVHESIEQLFFSIENKLGSRFVFRALGYVTMARAGLTEVELEDILSLDNSVLGDI 770
BLAST of GTPase activator protein vs. Ensembl Nematostella
Match: EDO37261 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SG70]) HSP 1 Score: 121.324 bits (303), Expect = 7.981e-33 Identity = 61/128 (47.66%), Postives = 88/128 (68.75%), Query Frame = 1 Query: 85 INIPKLESNISLLIIQQCLNRNCRSLTDVQWDIVKKTIRKCNLPLLVKITFDEISNWSSY-DILKTTLYETIEESIHNLLERIEISHGKILVMHALSYITASRTGISETELEDILSIDEIVLNDVYQY 465 I++P L + I+ L ++ R+L Q D+V +C LPL +KI+FDE W SY D +T LY ++ ++I+ LLERIE HG+ILV HAL Y+TA+R+G++ETEL+DILS D+ VL+DV+QY Sbjct: 462 ISVPSLPHSDVSDILSMWLQQSGRTLQPAQRDLVMSAFSQCPLPLFLKISFDEACRWHSYTDPGQTRLYGSVRDAINGLLERIEAKHGRILVQHALGYLTAARSGLTETELDDILSSDDEVLDDVFQY 589
BLAST of GTPase activator protein vs. Ensembl Nematostella
Match: EDO34994 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SMT6]) HSP 1 Score: 115.546 bits (288), Expect = 9.856e-31 Identity = 56/126 (44.44%), Postives = 86/126 (68.25%), Query Frame = 1 Query: 91 IPKLESNISLLIIQQCLNRNCRSLTDVQWDIVKKTIRKCNLPLLVKITFDEISNWSSYDIL-KTTLYETIEESIHNLLERIEISHGKILVMHALSYITASRTGISETELEDILSIDEIVLNDVYQY 465 +PKL + I+ L R+L+ Q DIV++ +++C+LP+ V++ FDE W SY L +T L T+ +I++L ER+E HG +LV AL Y+TA+++G++ETELED+LS D+ VL+DVYQY Sbjct: 473 VPKLPQKDAAEILVSYLRMEHRTLSTDQQDIVQQALQECSLPIFVRVAFDEAIRWKSYSPLDETVLQHTVRGAINSLFERVERQHGHVLVSRALGYVTAAKSGLTETELEDLLSCDDFVLDDVYQY 598
BLAST of GTPase activator protein vs. Ensembl Nematostella
Match: EDO40517 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S6Z9]) HSP 1 Score: 108.997 bits (271), Expect = 2.178e-28 Identity = 56/135 (41.48%), Postives = 84/135 (62.22%), Query Frame = 1 Query: 64 ILDESKIINIPKLESNISLLIIQQCLNRNCRSLTDVQWDIVKKTIRKCNLPLLVKITFDEISNWSSYDIL-KTTLYETIEESIHNLLERIEISHGKILVMHALSYITASRTGISETELEDILSIDEIVLNDVYQY 465 +LD + + + L S ++ I+ L+ + R LTD Q IV +C LPL +++ +D W SY L K+ L + ++ I L +R+E HG +LV HAL+YITA++ G+SE ELEDILS DE VL++V+QY Sbjct: 470 LLDSNCFVEVSSLPSEVACNILTSWLSNDNRRLTDSQRKIVLNAFNRCPLPLYLRLAYDHAVTWKSYTPLEKSVLEKNVQGMIKALFKRLERRHGTVLVRHALAYITAAKHGLSEPELEDILSCDEEVLDEVFQY 604
BLAST of GTPase activator protein vs. Ensembl Nematostella
Match: EDO31117 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SYV4]) HSP 1 Score: 108.612 bits (270), Expect = 3.508e-28 Identity = 58/143 (40.56%), Postives = 85/143 (59.44%), Query Frame = 1 Query: 40 ILTISNLTILDESKIINIPKLESNISLLIIQQCLNRNCRSLTDVQWDIVKKTIRKCNLPLLVKITFDEISNWSSY-DILKTTLYETIEESIHNLLERIEISHGKILVMHALSYITASRTGISETELEDILSIDEIVLNDVYQY 465 IL ++ D + I +P L + I+ L+ R+LT Q +V KC PL +K+ F E S W+SY D+ +L + E+I L ER+E HGK+L AL Y+TA+R+G++E ELEDILS+D+ V++DVYQY Sbjct: 506 ILPTLQRSLTDTNCYIEVPTLSRDTGHEILDAWLDSKHRTLTPEQRVLVMAAFDKCPQPLFLKLIFAEASEWASYTDVSGVSLGANVPEAIGFLFERLERKHGKMLFSRALQYVTAARSGLTENELEDILSLDDDVIDDVYQY 648
BLAST of GTPase activator protein vs. Ensembl Nematostella
Match: EDO47107 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RNA8]) HSP 1 Score: 77.7962 bits (190), Expect = 1.558e-17 Identity = 54/129 (41.86%), Postives = 81/129 (62.79%), Query Frame = 1 Query: 82 IINIPKLESNISLLIIQQCLNRNCRSLTDVQWDIVKKTIRKCNLPLLVKITFDEISNWSSYDILKTT-LYETIEESIHNLLERIEISHGKILVMHALSYITASRTGISETELEDILSIDEIVLNDVYQY 465 ++ +P++ + + LI+ L R+L Q + V + ++C LPL +K+ FDE W SY ++ L I + I L +R+E HGK LV H+L YITAS+ G++E ELED+LS+D+ VLNDVYQY Sbjct: 459 LMEVPQIPMSEAGLILDNWLKAANRALQPAQRNEVMISFKECPLPLYLKLAFDESCRWKSYTPMQDADLAPNITDIIRALFDRVERIHGKTLVSHSLGYITASKNGLTEPELEDLLSLDDDVLNDVYQY 587
BLAST of GTPase activator protein vs. Ensembl Medaka
Match: nwd2 (NACHT and WD repeat domain containing 2 [Source:NCBI gene;Acc:101165765]) HSP 1 Score: 81.2629 bits (199), Expect = 3.165e-18 Identity = 46/115 (40.00%), Postives = 67/115 (58.26%), Query Frame = 1 Query: 115 SLLIIQQCLNRNCRSLTDVQWDIVKKTIRKCNLPLLVKITFDEISNWSSY-DILKTTLYETIEESIHNLLERIEISHGKILVMHALSYITASRTGISETELEDILSIDEIVLNDV 456 S ++ QQ L R +T Q V + + KC LP+ V + + E+ +W S+ D+ +L T+ ESI L +E G+ V AL YIT ++ G++E ELEDILS+D IVL DV Sbjct: 570 SQMLKQQLLGVK-RKVTSGQQIYVNEALAKCTLPMFVNLIYREVVHWRSHKDVDDKSLCSTVHESIEQLFYSVENKLGQRFVFRALGYITMAKAGLTEVELEDILSLDNIVLGDV 683
BLAST of GTPase activator protein vs. Ensembl Medaka
Match: nwd2 (NACHT and WD repeat domain containing 2 [Source:NCBI gene;Acc:101165765]) HSP 1 Score: 81.2629 bits (199), Expect = 3.419e-18 Identity = 46/115 (40.00%), Postives = 67/115 (58.26%), Query Frame = 1 Query: 115 SLLIIQQCLNRNCRSLTDVQWDIVKKTIRKCNLPLLVKITFDEISNWSSY-DILKTTLYETIEESIHNLLERIEISHGKILVMHALSYITASRTGISETELEDILSIDEIVLNDV 456 S ++ QQ L R +T Q V + + KC LP+ V + + E+ +W S+ D+ +L T+ ESI L +E G+ V AL YIT ++ G++E ELEDILS+D IVL DV Sbjct: 580 SQMLKQQLLGVK-RKVTSGQQIYVNEALAKCTLPMFVNLIYREVVHWRSHKDVDDKSLCSTVHESIEQLFYSVENKLGQRFVFRALGYITMAKAGLTEVELEDILSLDNIVLGDV 693
BLAST of GTPase activator protein vs. Ensembl Medaka
Match: nwd2 (NACHT and WD repeat domain containing 2 [Source:NCBI gene;Acc:101165765]) HSP 1 Score: 81.2629 bits (199), Expect = 3.419e-18 Identity = 46/115 (40.00%), Postives = 67/115 (58.26%), Query Frame = 1 Query: 115 SLLIIQQCLNRNCRSLTDVQWDIVKKTIRKCNLPLLVKITFDEISNWSSY-DILKTTLYETIEESIHNLLERIEISHGKILVMHALSYITASRTGISETELEDILSIDEIVLNDV 456 S ++ QQ L R +T Q V + + KC LP+ V + + E+ +W S+ D+ +L T+ ESI L +E G+ V AL YIT ++ G++E ELEDILS+D IVL DV Sbjct: 580 SQMLKQQLLGVK-RKVTSGQQIYVNEALAKCTLPMFVNLIYREVVHWRSHKDVDDKSLCSTVHESIEQLFYSVENKLGQRFVFRALGYITMAKAGLTEVELEDILSLDNIVLGDV 693
BLAST of GTPase activator protein vs. Ensembl Medaka
Match: nwd1 (NACHT and WD repeat domain containing 1 [Source:ZFIN;Acc:ZDB-GENE-071116-8]) HSP 1 Score: 75.0998 bits (183), Expect = 3.929e-16 Identity = 47/160 (29.38%), Postives = 83/160 (51.88%), Query Frame = 1 Query: 16 NFPLRVRIILTIS-------NLTILDES--KIINIPKLESNISLLIIQQCLNRNCRSLTDVQWDIVKKTIRKCNLPLLVKITFDEISNWSSYDILKTTLY-ETIEESIHNLLERIEISHGKILVMHALSYITASRTGISETELEDILSIDEIVLNDVYQY 465 N P +V +++++ N+ + +S + +L + I++ L + R+LT Q D+ ++ PL +K+ + NW+S+ L L EE + LL R+E H K LV AL YI +R G+ E EL D++S+D+ V+++VY+Y Sbjct: 463 NLPPKVHLLVSMDTCSEAFVNMRLKTDSLENFFEVERLSRDEGERIMESHLRASQRTLTAEQKDVALQSFTLTGCPLHLKLILSAVQNWTSFTPLTEQLLGNNTEEVMSQLLHRLEHKHRKELVGGALGYIALARDGLLEAELYDVMSLDDDVISEVYRY 622
BLAST of GTPase activator protein vs. Ensembl Medaka
Match: ENSORLT00000012836.2 (NACHT and WD repeat domain-containing protein 2 [Source:NCBI gene;Acc:101161570]) HSP 1 Score: 64.3142 bits (155), Expect = 2.520e-12 Identity = 32/93 (34.41%), Postives = 55/93 (59.14%), Query Frame = 1 Query: 154 RSLTDVQWDIVKKTIRKCNLPLLVKITFDEISNWSS-YDILKTTLYETIEESIHNLLERIEISHGKILVMHALSYITASRTGISETELEDILS 429 R +T Q ++ + + C LPL ++ + WSS ++ ++ L + + SI LL+ +E+ HG LV A S++T S++G+SE EL D+LS Sbjct: 586 RRVTSGQQALINEALTSCRLPLYTRLLHVHAAGWSSDSEVNESFLPDGVHSSISALLDHLELKHGSALVARATSFLTLSKSGLSEAELADLLS 678
BLAST of GTPase activator protein vs. Planmine SMEST
Match: SMESG000018097.1 (SMESG000018097.1) HSP 1 Score: 306.99 bits (785), Expect = 1.455e-97 Identity = 154/156 (98.72%), Postives = 155/156 (99.36%), Query Frame = 1 Query: 1 GNFVINFPLRVRIILTISNLTILDESKIINIPKLESNISLLIIQQCLNRNCRSLTDVQWDIVKKTIRKCNLPLLVKITFDEISNWSSYDILKTTLYETIEESIHNLLERIEISHGKILVMHALSYITASRTGISETELEDILSIDEIVLNDVYQYH 468 GNFVINFPLRVRIILTISNLTILDESKIINIPKLESNISLLIIQQCLNRNCRSLTDVQW IVKKT+RKCNLPLLVKITFDEISNWSSYDILKTTLYETIEESIHNLLERIEISHGKILVMHALSYITASRTGISETELEDILSIDEIVLNDVYQYH Sbjct: 189 GNFVINFPLRVRIILTISNLTILDESKIINIPKLESNISLLIIQQCLNRNCRSLTDVQWGIVKKTLRKCNLPLLVKITFDEISNWSSYDILKTTLYETIEESIHNLLERIEISHGKILVMHALSYITASRTGISETELEDILSIDEIVLNDVYQYH 344
BLAST of GTPase activator protein vs. Planmine SMEST
Match: SMESG000018097.1 (SMESG000018097.1) HSP 1 Score: 305.834 bits (782), Expect = 7.636e-97 Identity = 154/156 (98.72%), Postives = 155/156 (99.36%), Query Frame = 1 Query: 1 GNFVINFPLRVRIILTISNLTILDESKIINIPKLESNISLLIIQQCLNRNCRSLTDVQWDIVKKTIRKCNLPLLVKITFDEISNWSSYDILKTTLYETIEESIHNLLERIEISHGKILVMHALSYITASRTGISETELEDILSIDEIVLNDVYQYH 468 GNFVINFPLRVRIILTISNLTILDESKIINIPKLESNISLLIIQQCLNRNCRSLTDVQW IVKKT+RKCNLPLLVKITFDEISNWSSYDILKTTLYETIEESIHNLLERIEISHGKILVMHALSYITASRTGISETELEDILSIDEIVLNDVYQYH Sbjct: 442 GNFVINFPLRVRIILTISNLTILDESKIINIPKLESNISLLIIQQCLNRNCRSLTDVQWGIVKKTLRKCNLPLLVKITFDEISNWSSYDILKTTLYETIEESIHNLLERIEISHGKILVMHALSYITASRTGISETELEDILSIDEIVLNDVYQYH 597
BLAST of GTPase activator protein vs. Planmine SMEST
Match: SMESG000074035.1 (SMESG000074035.1) HSP 1 Score: 73.9442 bits (180), Expect = 7.006e-16 Identity = 42/133 (31.58%), Postives = 75/133 (56.39%), Query Frame = 1 Query: 73 ESKIINIPKLESNISLLIIQQCLNRNCRSLTDVQWDIVKKTIRKCNLPLLVKITFDEISNWSSY-DILKTTLYETIEESIHNLLERIEISHGKILVMHALSYITASRTGISETELEDILSIDEIVLNDVYQYH 468 + K I+I + +LI Q L R+LTD+Q +++ + L +K+ ++ W SY + + + + +E +++ +E +G +L+ HAL Y+T G++E ELED+LS+ + VLN+VYQYH Sbjct: 581 QHKFIHINYFDDKEVVLICQSLLEHKKRTLTDLQMNLIISKLINNPRGLYIKLALEQAVTWKSYMSMEECIIKDCVESAVNFKFACLEEKYGLLLMSHALGYLTLGYNGLTEIELEDLLSLQDNVLNEVYQYH 713
BLAST of GTPase activator protein vs. Planmine SMEST
Match: SMESG000074035.1 (SMESG000074035.1) HSP 1 Score: 73.9442 bits (180), Expect = 7.059e-16 Identity = 42/133 (31.58%), Postives = 75/133 (56.39%), Query Frame = 1 Query: 73 ESKIINIPKLESNISLLIIQQCLNRNCRSLTDVQWDIVKKTIRKCNLPLLVKITFDEISNWSSY-DILKTTLYETIEESIHNLLERIEISHGKILVMHALSYITASRTGISETELEDILSIDEIVLNDVYQYH 468 + K I+I + +LI Q L R+LTD+Q +++ + L +K+ ++ W SY + + + + +E +++ +E +G +L+ HAL Y+T G++E ELED+LS+ + VLN+VYQYH Sbjct: 581 QHKFIHINYFDDKEVVLICQSLLEHKKRTLTDLQMNLIISKLINNPRGLYIKLALEQAVTWKSYMSMEECIIKDCVESAVNFKFACLEEKYGLLLMSHALGYLTLGYNGLTEIELEDLLSLQDNVLNEVYQYH 713
BLAST of GTPase activator protein vs. Planmine SMEST
Match: SMESG000074035.1 (SMESG000074035.1) HSP 1 Score: 73.9442 bits (180), Expect = 7.305e-16 Identity = 42/133 (31.58%), Postives = 75/133 (56.39%), Query Frame = 1 Query: 73 ESKIINIPKLESNISLLIIQQCLNRNCRSLTDVQWDIVKKTIRKCNLPLLVKITFDEISNWSSY-DILKTTLYETIEESIHNLLERIEISHGKILVMHALSYITASRTGISETELEDILSIDEIVLNDVYQYH 468 + K I+I + +LI Q L R+LTD+Q +++ + L +K+ ++ W SY + + + + +E +++ +E +G +L+ HAL Y+T G++E ELED+LS+ + VLN+VYQYH Sbjct: 610 QHKFIHINYFDDKEVVLICQSLLEHKKRTLTDLQMNLIISKLINNPRGLYIKLALEQAVTWKSYMSMEECIIKDCVESAVNFKFACLEEKYGLLLMSHALGYLTLGYNGLTEIELEDLLSLQDNVLNEVYQYH 742 The following BLAST results are available for this feature:
BLAST of GTPase activator protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of GTPase activator protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 1
BLAST of GTPase activator protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 1
BLAST of GTPase activator protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 4
BLAST of GTPase activator protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 4
BLAST of GTPase activator protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 4
BLAST of GTPase activator protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 4
BLAST of GTPase activator protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of GTPase activator protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of GTPase activator protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 0
BLAST of GTPase activator protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 0
BLAST of GTPase activator protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of GTPase activator protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of GTPase activator protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30028597 ID=SMED30028597|Name=GTPase activator protein|organism=Schmidtea mediterranea sexual|type=transcript|length=470bpback to top protein sequence of SMED30028597-orf-1 >SMED30028597-orf-1 ID=SMED30028597-orf-1|Name=SMED30028597-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=156bp GNFVINFPLRVRIILTISNLTILDESKIINIPKLESNISLLIIQQCLNRNback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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