GTPase activator protein

Overview
NameGTPase activator protein
Smed IDSMED30028597
Length (bp)470
Neoblast Clusters

Zeng et. al., 2018




▻ Overview

▻ Neoblast Population

 



 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)




Explore this single cell expression dataset with our NB Cluster Shiny App




 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of GTPase activator protein (SMED30028597) t-SNE clustered cells

Violin plots show distribution of expression levels for GTPase activator protein (SMED30028597) in cells (dots) of each of the 12 neoblast clusters.

 

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Embryonic Expression

Davies et. al., 2017




Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020




SMED30028597

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 8

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
X1 cellSMED30028597h1SMcG0003267 SmedASXL_012755SmedAsxl_ww_GCZZ01PMID:26114597
Zhu et al., 2015
FACS sorted cell population asexual adult RNA-sequencing evidence
X1 cellSMED30028597h1SMcG0003267 SmedASXL_004094SmedAsxl_ww_GCZZ01PMID:26114597
Zhu et al., 2015
FACS sorted cell population asexual adult RNA-sequencing evidence
nervous systemSMED30028597h1SMcG0003267 dd_Smed_v4_29867_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30028597h1SMcG0003267 dd_Smed_v4_29867_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
nervous systemSMED30028597h1SMcG0003267 dd_Smed_v4_74366_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30028597h1SMcG0003267 dd_Smed_v4_74366_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
zeta neoblastSMED30028597h1SMcG0003267 dd_Smed_v4_29867_0_1dd_Smed_v4PMID:28292427
Wurtzel et al., 2017
whole organism asexual adult single-cell RNA-sequencing evidence
zeta neoblastSMED30028597h1SMcG0003267 dd_Smed_v4_21908_0_1dd_Smed_v4PMID:28292427
Wurtzel et al., 2017
whole organism asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
BLAST of GTPase activator protein vs. Ensembl Human
Match: NWD1 (NACHT and WD repeat domain containing 1 [Source:HGNC Symbol;Acc:HGNC:27619])

HSP 1 Score: 97.4413 bits (241), Expect = 1.225e-23
Identity = 55/160 (34.38%), Postives = 88/160 (55.00%), Query Frame = 1
Query:   13 INFPLRVRIILTISN----------LTILDESKIINIPKLESNISLLIIQQCLNRNCRSLTDVQWDIVKKTIRKCNLPLLVKITFDEISNWSSYDILKTTLYETIEESIHNLLERIEISHGKILVMHALSYITASRTGISETELEDILSIDEIVLNDVYQ 462
            +N P RV +IL+  +            +LD      +  L  N    +IQ  L    R+L+ V  D++  ++ +C  P  +++ F+E   W+S+ +    L  T EE+ H L  R+E +HG++LV H L YI +SR G+SE EL+D+LS+D+ VL DVY+
Sbjct:  456 LNCPPRVHLILSACSGALGVLDTLQRVLLDPEAYWEVKPLSGNQGQQMIQLLLAAARRTLSPVHTDLLWASLPECGNPGRLRLAFEEARKWASFTV-PVPLATTAEEATHQLCTRLEQTHGQLLVAHVLGYIVSSRHGLSEAELKDVLSLDDEVLQDVYR 614          
BLAST of GTPase activator protein vs. Ensembl Human
Match: NWD1 (NACHT and WD repeat domain containing 1 [Source:HGNC Symbol;Acc:HGNC:27619])

HSP 1 Score: 97.4413 bits (241), Expect = 1.225e-23
Identity = 55/160 (34.38%), Postives = 88/160 (55.00%), Query Frame = 1
Query:   13 INFPLRVRIILTISN----------LTILDESKIINIPKLESNISLLIIQQCLNRNCRSLTDVQWDIVKKTIRKCNLPLLVKITFDEISNWSSYDILKTTLYETIEESIHNLLERIEISHGKILVMHALSYITASRTGISETELEDILSIDEIVLNDVYQ 462
            +N P RV +IL+  +            +LD      +  L  N    +IQ  L    R+L+ V  D++  ++ +C  P  +++ F+E   W+S+ +    L  T EE+ H L  R+E +HG++LV H L YI +SR G+SE EL+D+LS+D+ VL DVY+
Sbjct:  456 LNCPPRVHLILSACSGALGVLDTLQRVLLDPEAYWEVKPLSGNQGQQMIQLLLAAARRTLSPVHTDLLWASLPECGNPGRLRLAFEEARKWASFTV-PVPLATTAEEATHQLCTRLEQTHGQLLVAHVLGYIVSSRHGLSEAELKDVLSLDDEVLQDVYR 614          
BLAST of GTPase activator protein vs. Ensembl Human
Match: NWD1 (NACHT and WD repeat domain containing 1 [Source:HGNC Symbol;Acc:HGNC:27619])

HSP 1 Score: 97.4413 bits (241), Expect = 1.225e-23
Identity = 55/160 (34.38%), Postives = 88/160 (55.00%), Query Frame = 1
Query:   13 INFPLRVRIILTISN----------LTILDESKIINIPKLESNISLLIIQQCLNRNCRSLTDVQWDIVKKTIRKCNLPLLVKITFDEISNWSSYDILKTTLYETIEESIHNLLERIEISHGKILVMHALSYITASRTGISETELEDILSIDEIVLNDVYQ 462
            +N P RV +IL+  +            +LD      +  L  N    +IQ  L    R+L+ V  D++  ++ +C  P  +++ F+E   W+S+ +    L  T EE+ H L  R+E +HG++LV H L YI +SR G+SE EL+D+LS+D+ VL DVY+
Sbjct:  456 LNCPPRVHLILSACSGALGVLDTLQRVLLDPEAYWEVKPLSGNQGQQMIQLLLAAARRTLSPVHTDLLWASLPECGNPGRLRLAFEEARKWASFTV-PVPLATTAEEATHQLCTRLEQTHGQLLVAHVLGYIVSSRHGLSEAELKDVLSLDDEVLQDVYR 614          
BLAST of GTPase activator protein vs. Ensembl Human
Match: NWD1 (NACHT and WD repeat domain containing 1 [Source:HGNC Symbol;Acc:HGNC:27619])

HSP 1 Score: 97.4413 bits (241), Expect = 1.230e-23
Identity = 55/160 (34.38%), Postives = 88/160 (55.00%), Query Frame = 1
Query:   13 INFPLRVRIILTISN----------LTILDESKIINIPKLESNISLLIIQQCLNRNCRSLTDVQWDIVKKTIRKCNLPLLVKITFDEISNWSSYDILKTTLYETIEESIHNLLERIEISHGKILVMHALSYITASRTGISETELEDILSIDEIVLNDVYQ 462
            +N P RV +IL+  +            +LD      +  L  N    +IQ  L    R+L+ V  D++  ++ +C  P  +++ F+E   W+S+ +    L  T EE+ H L  R+E +HG++LV H L YI +SR G+SE EL+D+LS+D+ VL DVY+
Sbjct:  456 LNCPPRVHLILSACSGALGVLDTLQRVLLDPEAYWEVKPLSGNQGQQMIQLLLAAARRTLSPVHTDLLWASLPECGNPGRLRLAFEEARKWASFTV-PVPLATTAEEATHQLCTRLEQTHGQLLVAHVLGYIVSSRHGLSEAELKDVLSLDDEVLQDVYR 614          
BLAST of GTPase activator protein vs. Ensembl Human
Match: NWD1 (NACHT and WD repeat domain containing 1 [Source:HGNC Symbol;Acc:HGNC:27619])

HSP 1 Score: 97.4413 bits (241), Expect = 1.232e-23
Identity = 55/160 (34.38%), Postives = 88/160 (55.00%), Query Frame = 1
Query:   13 INFPLRVRIILTISN----------LTILDESKIINIPKLESNISLLIIQQCLNRNCRSLTDVQWDIVKKTIRKCNLPLLVKITFDEISNWSSYDILKTTLYETIEESIHNLLERIEISHGKILVMHALSYITASRTGISETELEDILSIDEIVLNDVYQ 462
            +N P RV +IL+  +            +LD      +  L  N    +IQ  L    R+L+ V  D++  ++ +C  P  +++ F+E   W+S+ +    L  T EE+ H L  R+E +HG++LV H L YI +SR G+SE EL+D+LS+D+ VL DVY+
Sbjct:  456 LNCPPRVHLILSACSGALGVLDTLQRVLLDPEAYWEVKPLSGNQGQQMIQLLLAAARRTLSPVHTDLLWASLPECGNPGRLRLAFEEARKWASFTV-PVPLATTAEEATHQLCTRLEQTHGQLLVAHVLGYIVSSRHGLSEAELKDVLSLDDEVLQDVYR 614          
BLAST of GTPase activator protein vs. Ensembl Celegans
Match: T05C3.2 (pep chromosome:WBcel235:V:5493747:5503010:1 gene:WBGene00020254.1 transcript:T05C3.2.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:T05C3.2)

HSP 1 Score: 127.872 bits (320), Expect = 1.116e-34
Identity = 56/136 (41.18%), Postives = 96/136 (70.59%), Query Frame = 1
Query:   64 ILDESKIINIPKLESNISLLIIQQCLNRNCRSLTDVQWDIVKKTIRKCNLPLLVKITFDEISNWSSYDILKTT-LYETIEESIHNLLERIEISHGKILVMHALSYITASRTGISETELEDILSIDEIVLNDVYQYH 468
            I D+ + + +P L  ++   ++++ L+   R+L++ QW+ V K + KC LPL VK+ +  ++ W SY   + T L+ +++ESI+ L  R E  HGK+LV HALSYI+A+R+GIS++E+ED++S+D+ VL+D++QYH
Sbjct:  605 IEDKRQYLMVPSLGKDLGFQVVREWLSDKGRTLSERQWNTVSKALDKCTLPLFVKLIYATVARWKSYSRPQETILFSSLQESINVLFHRTESQHGKLLVSHALSYISAARSGISDSEVEDLISLDDKVLDDIFQYH 740          
BLAST of GTPase activator protein vs. Ensembl Fly
Match: CG10185 (gene:FBgn0038397 transcript:FBtr0083235)

HSP 1 Score: 130.568 bits (327), Expect = 1.851e-35
Identity = 62/133 (46.62%), Postives = 90/133 (67.67%), Query Frame = 1
Query:   73 ESKIINIPKLESNISLLIIQQCLNRNCRSLTDVQWDIVKKTIRKCNLPLLVKITFDEISNWSSYDILKTT-LYETIEESIHNLLERIEISHGKILVMHALSYITASRTGISETELEDILSIDEIVLNDVYQYH 468
            E   I +  L  ++++ +I+  +   CR L + QW +V   I KC+LP+ VK+ F EI  W SY   + T L  T+ +SI  L ER+E  HG+ILV HAL+YITAS++G+SE+ELED++S+D+ VL+DVYQYH
Sbjct:  537 EENFIEVTALGEDLAMNVIKMWMKTACRDLNNYQWRLVANAISKCSLPIFVKLVFAEICRWRSYTRPQETHLANTVMDSIMLLFERVEKQHGRILVFHALAYITASKSGLSESELEDLISLDDKVLDDVYQYH 669          
BLAST of GTPase activator protein vs. Ensembl Zebrafish
Match: nwd1 (NACHT and WD repeat domain containing 1 [Source:ZFIN;Acc:ZDB-GENE-071116-8])

HSP 1 Score: 82.8037 bits (203), Expect = 9.141e-19
Identity = 56/156 (35.90%), Postives = 87/156 (55.77%), Query Frame = 1
Query:   22 PLRVRIILTISNLTILDESKII-----NIPKLE---SNISLLIIQQCLNRNCRSLTDVQWDIVKKTIRKCNLPLLVKITFDEISNWSSYDILKTT-LYETIEESIHNLLERIEISHGKILVMHALSYITASRTGISETELEDILSIDEIVLNDVYQ 462
            P  V+I+ + SN   LD+ K +     NI KLE    +    +I   ++   R LT  Q D + +   +   PL +K+  D    WSSY  + +  L ++ EE +   +E +E++HGK LV HALS+I  SR G+SE EL+D+LS+D  VL ++Y+
Sbjct:  518 PPNVQIVFSTSN-ECLDKCKSLVSAEENIFKLELLTKDQGRDVIDAYMSAAERKLTAEQQDAILRYFEQSGNPLHLKLMLDTAKLWSSYTPMSSVHLDKSAEEVMTQFVESLEVNHGKKLVSHALSFILLSRYGLSEAELQDVLSLDNDVLAEIYK 672          
BLAST of GTPase activator protein vs. Ensembl Zebrafish
Match: nwd2 (NACHT and WD repeat domain containing 2 [Source:ZFIN;Acc:ZDB-GENE-161213-1])

HSP 1 Score: 78.9518 bits (193), Expect = 2.693e-17
Identity = 52/159 (32.70%), Postives = 81/159 (50.94%), Query Frame = 1
Query:   13 INFPLRVRIIL-TISN---------LTILDESKIINIPKLESNISLLIIQQCLNRNCRSLTDVQWDIVKKTIRKCNLPLLVKITFDEISNWSSY-DILKTTLYETIEESIHNLLERIEISHGKILVMHALSYITASRTGISETELEDILSIDEIVLNDV 456
            ++ P  VRI++ T+ N           I DE   + + + +       ++Q L    R +T  Q   V + + KC LP+ V + + E+ +W S+ D+   +L  T+ ESI  L   +E   G   V  AL YIT +R G++E ELEDILS+D  VL D+
Sbjct:  535 VHLPRTVRIVVSTLPNKHGILQKLRCLIHDEEAYVELMQRDRKACSQTLKQQLLGVKRKVTSGQQIYVNEAMAKCTLPMFVNLIYREVVHWRSHKDVDDKSLCSTVHESIEQLFYSVENKLGSRFVFRALGYITMARAGLTELELEDILSLDNSVLGDI 693          
BLAST of GTPase activator protein vs. Ensembl Zebrafish
Match: CU570791.3 (NACHT and WD repeat domain-containing protein 2-like [Source:NCBI gene;Acc:108179119])

HSP 1 Score: 65.0846 bits (157), Expect = 1.776e-12
Identity = 36/99 (36.36%), Postives = 59/99 (59.60%), Query Frame = 1
Query:  154 RSLTDVQWDIVKKTIRKCNLPLLVKITFDEISNW-SSYDILKTTLYETIEESIHNLLERIEISHGKILVMHALSYITASRTGISETELEDILSIDEIVL 447
            R +T  Q   V + ++KC +PL V++ + +   W S ++I + TL   +  SI  + + +E  HGK LV  ALSY+T +R G++  EL D+LS D+ V+
Sbjct:  513 RKITSGQQVYVNEALKKCTVPLYVELLYRQAVCWHSEFEITEETLDLEVHNSIVLIFDHMERKHGKSLVSKALSYLTLARYGMTTAELTDVLSCDDEVV 611          
BLAST of GTPase activator protein vs. Ensembl Zebrafish
Match: si:ch211-212k18.6 (si:ch211-212k18.6 [Source:ZFIN;Acc:ZDB-GENE-130530-938])

HSP 1 Score: 47.7506 bits (112), Expect = 1.616e-6
Identity = 33/130 (25.38%), Postives = 61/130 (46.92%), Query Frame = 1
Query:   82 IINIPKLESNISLLIIQQCLNRNCRSLTDVQWDIVKKTIRKCNLPLLVKITFDEISNWSSYDILKT-TLYETIEESIHNLLERIEISHGKILVMHALSYITASRTGISETELEDILSIDEIVLNDVYQYH 468
            ++++P L        +   L+ + R LT+ QW ++ ++   C  PL + + + E   WSS+       + +   +   N+L  +E  +G  LV      I+ SR+GI+E EL  +L  D  V  ++   H
Sbjct:  813 VLSLPALHHEEITSALASRLSSDSRQLTENQWTLLSQSCLSCPSPLYLNLAYAESKQWSSFTPENNLNIPKDPNQLFINVLVSLEREYGSCLVRRLALLISLSRSGIAEEELLVLLGCDGHVKREMASLH 942          
BLAST of GTPase activator protein vs. Ensembl Xenopus
Match: ppp1r3c.1 (protein phosphatase 1, regulatory (inhibitor) subunit 3C, gene 1 [Source:Xenbase;Acc:XB-GENE-969181])

HSP 1 Score: 108.997 bits (271), Expect = 1.232e-27
Identity = 61/153 (39.87%), Postives = 91/153 (59.48%), Query Frame = 1
Query:   10 VINFPLRVRIILTISNLTILDESKIINIPKLESNISLLIIQQCLNRNCRSLTDVQWDIVKKTIRKCNLPLLVKITFDEISNWSSY-DILKTTLYETIEESIHNLLERIEISHGKILVMHALSYITASRTGISETELEDILSIDEIVLNDVYQY 465
            V   P    I+ T+ + ++ D    I +  L +     +I+  +    R LT+ Q +IV  + RKC  PLL+K+ FDE   WSSY  I +  +  + +E++  L + +E  HGK+LV HAL YI ASR+G+SE EL+DILS+D+ VL D+YQY
Sbjct:  458 VSTLPEEGGILKTLKD-SVTDPECYIEVKPLSAEQGSQMIEMLMASAGRRLTNDQQEIVLGSFRKCGQPLLLKLAFDEAKRWSSYTPITELMIATSTKEAVSLLYQCLEQLHGKLLVSHALGYIVASRSGLSEAELKDILSLDDEVLADIYQY 609          
BLAST of GTPase activator protein vs. Ensembl Xenopus
Match: hsp90ab1 (heat shock protein 90kDa alpha family class B member 1 [Source:Xenbase;Acc:XB-GENE-495311])

HSP 1 Score: 81.2629 bits (199), Expect = 5.461e-18
Identity = 57/160 (35.62%), Postives = 86/160 (53.75%), Query Frame = 1
Query:   13 INFPLRVRIILT--------ISNLTIL---DESKIINIPKLESNISLLIIQQCLNRNCRSLTDVQWDIVKKTIRKCNLPLLVKITFDEISNWSSY-DILKTTLYETIEESIHNLLERIEISHGKILVMHALSYITASRTGISETELEDILSIDEIVLNDV 456
            ++ P  VRII++        +  L  L   ++S I  IP+ +   S ++  Q L R  R +T  Q   V +   KC LP+ V +TF E+ NW S+ D+  +TL  T+  +I  L   +E   G   V  AL YIT + TG+SE ELEDIL++D  V+++V
Sbjct:  532 VHLPRTVRIIISTLPNKHGILQKLRCLIHNEDSYIELIPRDKKMCSQILKHQLL-RVKRKVTSGQQIYVNEAFSKCTLPMFVNLTFREVRNWRSHKDVDGSTLCVTVHRNIEQLFWSLENKCGPRFVSRALGYITMATTGLSEVELEDILALDNTVMSEV 690          
BLAST of GTPase activator protein vs. Ensembl Xenopus
Match: ENSXETT00000022477.1 (pep primary_assembly:Xenopus_tropicalis_v9.1:KV460486.1:142089:157740:1 gene:ENSXETG00000010819.1 transcript:ENSXETT00000022477.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 65.4698 bits (158), Expect = 1.466e-12
Identity = 38/113 (33.63%), Postives = 63/113 (55.75%), Query Frame = 1
Query:  127 IQQCLNRNCRSLTDVQWDIVKKTIRKCNLPLLVKITFDEISNWSSY-DILKTTLYETIEESIHNLLERIEISHGKILVMHALSYITASRTGISETELEDILSIDEIVLNDVYQ 462
            ++ CL    R +T  Q   V +++     PL V + F  ++ W S+ D+   TL E   E+   L  ++EI +G+ +V   LSYIT S++GI  TEL D+L+ D++VL   ++
Sbjct:  513 LKHCLLGCYRKITSGQQMYVNRSLETNTSPLQVHLLFKLVAEWKSHQDVDNQTLGEDTYEAAERLFHKLEIKYGREIVSRTLSYITLSQSGIGVTELVDLLTADDLVLEKFHE 625          
BLAST of GTPase activator protein vs. Ensembl Xenopus
Match: ENSXETT00000003639.1 (uncharacterized LOC101730828 [Source:NCBI gene;Acc:101730828])

HSP 1 Score: 50.447 bits (119), Expect = 2.319e-7
Identity = 45/145 (31.03%), Postives = 76/145 (52.41%), Query Frame = 1
Query:   46 TISNLTILDESKIINIPKLESNISLLIIQQCLNRNCRSLTDVQWDIVKKTIRKCNLPLLVKITFDEISNWSSYDILKTTLYETIEESIHNL----LERIEISHGKILVMHALSYITASRTGISETELEDILSIDEIVLNDVYQYH 468
            T+  LT+  +  +  IP L+S     +I+  + R+ R LT  Q  ++      C LPL V  ++ E   W+SY     +    ++ ++H L    L R+E SHG+ ++    SYI+ S+ G++  EL D+LS+D  V+ +V QY 
Sbjct:  157 TLQKLTM--QQNVHQIPPLDSEEIRNMIEVWMERDNRRLTGRQKKVLFDACAACPLPLYVVSSYMESCLWTSYSSESDSY---LQPNLHKLYSAVLGRLEKSHGEQVMKMVASYISLSKNGVTLEELLDLLSLDLGVMQEVKQYQ 296          
BLAST of GTPase activator protein vs. Ensembl Mouse
Match: Nwd1 (NACHT and WD repeat domain containing 1 [Source:MGI Symbol;Acc:MGI:2442268])

HSP 1 Score: 89.7373 bits (221), Expect = 4.480e-21
Identity = 55/156 (35.26%), Postives = 85/156 (54.49%), Query Frame = 1
Query:   22 PLRVRIILT-------ISNL--TILDESKIINIPKLESNISLLIIQQCLNRNCRSLTDVQWDIVKKTIRKCNLPLLVKITFDEISNWSSYDILKTTLYETIEESIHNLLERIEISHGKILVMHALSYITASRTGISETELEDILSIDEIVLNDVYQ 462
            P RV +IL+       + NL  T+ D S    +  L  +     IQ  L    R L+  Q D++  ++ +C  P  +++ F+E   W+S+ +    L  T EE+ H L  R+E +HG +LV H L YI +SR G+SE EL+D+LS+D+ VL  VY+
Sbjct:  460 PPRVHLILSTCSGQQVLHNLQQTLKDPSTYWEVKALSGSQGQEFIQLLLAAEKRMLSPGQRDVLWASLPECGHPGRLRLAFEEARKWASFTV-PVPLATTAEEATHQLCIRLEETHGALLVAHVLGYIVSSRYGLSEAELKDVLSLDDEVLQAVYR 614          
BLAST of GTPase activator protein vs. Ensembl Mouse
Match: Nwd1 (NACHT and WD repeat domain containing 1 [Source:MGI Symbol;Acc:MGI:2442268])

HSP 1 Score: 89.7373 bits (221), Expect = 4.488e-21
Identity = 55/156 (35.26%), Postives = 85/156 (54.49%), Query Frame = 1
Query:   22 PLRVRIILT-------ISNL--TILDESKIINIPKLESNISLLIIQQCLNRNCRSLTDVQWDIVKKTIRKCNLPLLVKITFDEISNWSSYDILKTTLYETIEESIHNLLERIEISHGKILVMHALSYITASRTGISETELEDILSIDEIVLNDVYQ 462
            P RV +IL+       + NL  T+ D S    +  L  +     IQ  L    R L+  Q D++  ++ +C  P  +++ F+E   W+S+ +    L  T EE+ H L  R+E +HG +LV H L YI +SR G+SE EL+D+LS+D+ VL  VY+
Sbjct:  501 PPRVHLILSTCSGQQVLHNLQQTLKDPSTYWEVKALSGSQGQEFIQLLLAAEKRMLSPGQRDVLWASLPECGHPGRLRLAFEEARKWASFTV-PVPLATTAEEATHQLCIRLEETHGALLVAHVLGYIVSSRYGLSEAELKDVLSLDDEVLQAVYR 655          
BLAST of GTPase activator protein vs. Ensembl Mouse
Match: Nwd1 (NACHT and WD repeat domain containing 1 [Source:MGI Symbol;Acc:MGI:2442268])

HSP 1 Score: 89.7373 bits (221), Expect = 4.488e-21
Identity = 55/156 (35.26%), Postives = 85/156 (54.49%), Query Frame = 1
Query:   22 PLRVRIILT-------ISNL--TILDESKIINIPKLESNISLLIIQQCLNRNCRSLTDVQWDIVKKTIRKCNLPLLVKITFDEISNWSSYDILKTTLYETIEESIHNLLERIEISHGKILVMHALSYITASRTGISETELEDILSIDEIVLNDVYQ 462
            P RV +IL+       + NL  T+ D S    +  L  +     IQ  L    R L+  Q D++  ++ +C  P  +++ F+E   W+S+ +    L  T EE+ H L  R+E +HG +LV H L YI +SR G+SE EL+D+LS+D+ VL  VY+
Sbjct:  460 PPRVHLILSTCSGQQVLHNLQQTLKDPSTYWEVKALSGSQGQEFIQLLLAAEKRMLSPGQRDVLWASLPECGHPGRLRLAFEEARKWASFTV-PVPLATTAEEATHQLCIRLEETHGALLVAHVLGYIVSSRYGLSEAELKDVLSLDDEVLQAVYR 614          
BLAST of GTPase activator protein vs. Ensembl Mouse
Match: Nwd2 (NACHT and WD repeat domain containing 2 [Source:MGI Symbol;Acc:MGI:1920464])

HSP 1 Score: 80.8777 bits (198), Expect = 5.368e-18
Identity = 47/123 (38.21%), Postives = 72/123 (58.54%), Query Frame = 1
Query:   91 IPKLESNISLLIIQQCLNRNCRSLTDVQWDIVKKTIRKCNLPLLVKITFDEISNWSSY-DILKTTLYETIEESIHNLLERIEISHGKILVMHALSYITASRTGISETELEDILSIDEIVLNDV 456
            IP+     S ++  Q L R  R +T  Q   V     KC LP+ V +TF E+ +W S+ D+ +++L  T+ ESI  L   +E   G+ LV  AL YIT ++ G+SE ELED+L++D  V+N++
Sbjct:  570 IPRDRKMCSQVLKHQLL-RVKRKVTSGQQIYVNNAFSKCTLPMFVNLTFREVRHWRSHKDVDESSLCVTVHESIEQLFWSLEKKCGQKLVSRALGYITMAKMGLSEMELEDVLALDNSVMNEL 691          
BLAST of GTPase activator protein vs. UniProt/SwissProt
Match: sp|Q149M9|NWD1_HUMAN (NACHT domain- and WD repeat-containing protein 1 OS=Homo sapiens OX=9606 GN=NWD1 PE=1 SV=3)

HSP 1 Score: 97.4413 bits (241), Expect = 5.918e-23
Identity = 55/160 (34.38%), Postives = 88/160 (55.00%), Query Frame = 1
Query:   13 INFPLRVRIILTISN----------LTILDESKIINIPKLESNISLLIIQQCLNRNCRSLTDVQWDIVKKTIRKCNLPLLVKITFDEISNWSSYDILKTTLYETIEESIHNLLERIEISHGKILVMHALSYITASRTGISETELEDILSIDEIVLNDVYQ 462
            +N P RV +IL+  +            +LD      +  L  N    +IQ  L    R+L+ V  D++  ++ +C  P  +++ F+E   W+S+ +    L  T EE+ H L  R+E +HG++LV H L YI +SR G+SE EL+D+LS+D+ VL DVY+
Sbjct:  456 LNCPPRVHLILSACSGALGVLDTLQRVLLDPEAYWEVKPLSGNQGQQMIQLLLAAARRTLSPVHTDLLWASLPECGNPGRLRLAFEEARKWASFTV-PVPLATTAEEATHQLCTRLEQTHGQLLVAHVLGYIVSSRHGLSEAELKDVLSLDDEVLQDVYR 614          
BLAST of GTPase activator protein vs. UniProt/SwissProt
Match: sp|A6H603|NWD1_MOUSE (NACHT domain- and WD repeat-containing protein 1 OS=Mus musculus OX=10090 GN=Nwd1 PE=2 SV=2)

HSP 1 Score: 89.7373 bits (221), Expect = 3.139e-20
Identity = 55/156 (35.26%), Postives = 85/156 (54.49%), Query Frame = 1
Query:   22 PLRVRIILT-------ISNL--TILDESKIINIPKLESNISLLIIQQCLNRNCRSLTDVQWDIVKKTIRKCNLPLLVKITFDEISNWSSYDILKTTLYETIEESIHNLLERIEISHGKILVMHALSYITASRTGISETELEDILSIDEIVLNDVYQ 462
            P RV +IL+       + NL  T+ D S    +  L  +     IQ  L    R L+  Q D++  ++ +C  P  +++ F+E   W+S+ +    L  T EE+ H L  R+E +HG +LV H L YI +SR G+SE EL+D+LS+D+ VL  VY+
Sbjct:  460 PPRVHLILSTCSGQQVLHNLQQTLKDPSTYWEVKALSGSQGQEFIQLLLAAEKRMLSPGQRDVLWASLPECGHPGRLRLAFEEARKWASFTV-PVPLATTAEEATHQLCIRLEETHGALLVAHVLGYIVSSRYGLSEAELKDVLSLDDEVLQAVYR 614          
BLAST of GTPase activator protein vs. UniProt/SwissProt
Match: sp|Q6P5U7|NWD2_MOUSE (NACHT and WD repeat domain-containing protein 2 OS=Mus musculus OX=10090 GN=Nwd2 PE=1 SV=2)

HSP 1 Score: 80.8777 bits (198), Expect = 3.755e-17
Identity = 47/123 (38.21%), Postives = 72/123 (58.54%), Query Frame = 1
Query:   91 IPKLESNISLLIIQQCLNRNCRSLTDVQWDIVKKTIRKCNLPLLVKITFDEISNWSSY-DILKTTLYETIEESIHNLLERIEISHGKILVMHALSYITASRTGISETELEDILSIDEIVLNDV 456
            IP+     S ++  Q L R  R +T  Q   V     KC LP+ V +TF E+ +W S+ D+ +++L  T+ ESI  L   +E   G+ LV  AL YIT ++ G+SE ELED+L++D  V+N++
Sbjct:  570 IPRDRKMCSQVLKHQLL-RVKRKVTSGQQIYVNNAFSKCTLPMFVNLTFREVRHWRSHKDVDESSLCVTVHESIEQLFWSLEKKCGQKLVSRALGYITMAKMGLSEMELEDVLALDNSVMNEL 691          
BLAST of GTPase activator protein vs. UniProt/SwissProt
Match: sp|Q9ULI1|NWD2_HUMAN (NACHT and WD repeat domain-containing protein 2 OS=Homo sapiens OX=9606 GN=NWD2 PE=2 SV=3)

HSP 1 Score: 79.337 bits (194), Expect = 1.207e-16
Identity = 46/123 (37.40%), Postives = 73/123 (59.35%), Query Frame = 1
Query:   91 IPKLESNISLLIIQQCLNRNCRSLTDVQWDIVKKTIRKCNLPLLVKITFDEISNWSSY-DILKTTLYETIEESIHNLLERIEISHGKILVMHALSYITASRTGISETELEDILSIDEIVLNDV 456
            IP+     S ++  Q L R  R +T  Q   V   + KC LP+ V +TF E+ +W S+ D+ +++L  T+ ESI  L   +E   G+ LV  AL YIT ++ G+SE ELED+L++D  V++++
Sbjct:  570 IPRDRKMCSQVLKHQLL-RVKRKVTSGQQIYVNNALSKCTLPMFVNLTFREVRHWRSHKDVDESSLSVTVHESIEQLFWSLEKKCGQKLVSRALGYITMAKMGLSEMELEDVLALDNSVMSEL 691          
BLAST of GTPase activator protein vs. TrEMBL
Match: R7U0H5 (Uncharacterized protein (Fragment) OS=Capitella teleta OX=283909 GN=CAPTEDRAFT_120102 PE=4 SV=1)

HSP 1 Score: 147.517 bits (371), Expect = 2.094e-41
Identity = 72/136 (52.94%), Postives = 94/136 (69.12%), Query Frame = 1
Query:   64 ILDESKIINIPKLESNISLLIIQQCLNRNCRSLTDVQWDIVKKTIRKCNLPLLVKITFDEISNWSSYDILK-TTLYETIEESIHNLLERIEISHGKILVMHALSYITASRTGISETELEDILSIDEIVLNDVYQYH 468
            I  E   + I  L  N+   I++  L+R  R+++D QW +V + I KCNLPL VK+ FDEIS W SY  +K TTL  +I  SI+ L +RIE+ HGK+LV  AL YITA++ G+SE ELED+LS+DE VLNDVYQYH
Sbjct:   12 ITAEKNFVEITPLGRNLGSTILKSWLDRANRTVSDEQWGVVTEAIEKCNLPLYVKLVFDEISQWRSYSSVKATTLAHSIHASINKLFDRIEMQHGKVLVARALGYITAAKGGLSEAELEDLLSLDEKVLNDVYQYH 147          
BLAST of GTPase activator protein vs. TrEMBL
Match: R7TPK7 (Uncharacterized protein OS=Capitella teleta OX=283909 GN=CAPTEDRAFT_169319 PE=4 SV=1)

HSP 1 Score: 147.132 bits (370), Expect = 7.262e-38
Identity = 72/136 (52.94%), Postives = 94/136 (69.12%), Query Frame = 1
Query:   64 ILDESKIINIPKLESNISLLIIQQCLNRNCRSLTDVQWDIVKKTIRKCNLPLLVKITFDEISNWSSYDILK-TTLYETIEESIHNLLERIEISHGKILVMHALSYITASRTGISETELEDILSIDEIVLNDVYQYH 468
            I  E   + I  L  N+   I++  L+R  R+++D QW +V + I KCNLPL VK+ FDEIS W SY  +K TTL  +I  SI+ L +RIE+ HGK+LV  AL YITA++ G+SE ELED+LS+DE VLNDVYQYH
Sbjct:  540 ITAEKNFVEITPLGRNLGSTILKSWLDRANRTVSDEQWGVVTEAIEKCNLPLYVKLVFDEISQWRSYSSVKATTLAHSIHASINKLFDRIEMQHGKVLVARALGYITAAKGGLSEAELEDLLSLDEKVLNDVYQYH 675          
BLAST of GTPase activator protein vs. TrEMBL
Match: A0A210PU69 (Uncharacterized protein OS=Mizuhopecten yessoensis OX=6573 GN=KP79_PYT19717 PE=4 SV=1)

HSP 1 Score: 145.206 bits (365), Expect = 3.803e-37
Identity = 75/150 (50.00%), Postives = 100/150 (66.67%), Query Frame = 1
Query:   22 PLRVRIILTISNLTILDESKIINIPKLESNISLLIIQQCLNRNCRSLTDVQWDIVKKTIRKCNLPLLVKITFDEISNWSSYDILKTTLYE-TIEESIHNLLERIEISHGKILVMHALSYITASRTGISETELEDILSIDEIVLNDVYQYH 468
            P    I+ TI  +   DE+ +  +P L  N+S  I++  L    +++TD QWD+V +   KCNLPL+VK+ FD+I  W SY    TT+ + TI +SI  L ERIEI HGK LV HA  YITA ++G+SE+ELED+LS+DE VLNDVYQYH
Sbjct:  538 PRLYGILDTIRIMIEPDENYVAVLP-LGENLSGTILKFWLKNGNKAITDAQWDLVNEAFTKCNLPLMVKLVFDQICTWKSYTKPSTTVLQFTIHDSIMKLYERIEIQHGKTLVAHAFGYITAGKSGVSESELEDLLSLDEKVLNDVYQYH 686          
BLAST of GTPase activator protein vs. TrEMBL
Match: A0A1S3KFF1 (NACHT and WD repeat domain-containing protein 2 OS=Lingula unguis OX=7574 GN=LOC106181362 PE=4 SV=1)

HSP 1 Score: 143.665 bits (361), Expect = 1.314e-36
Identity = 82/163 (50.31%), Postives = 105/163 (64.42%), Query Frame = 1
Query:   13 INFPLRVRIIL-TISN-LTILD--------ESKIINIPKLESNISLLIIQQCLNRNCRSLTDVQWDIVKKTIRKCNLPLLVKITFDEISNWSSYDILK-TTLYETIEESIHNLLERIEISHGKILVMHALSYITASRTGISETELEDILSIDEIVLNDVYQYH 468
            ++ P  VRII+ T+ N  +ILD        E   + I  L  ++   I++  L R  RS+T+ QW IV + I KCNLPL VK+  DEI  W SY   + TTL  TI ++I  L +RIEI HGK LV HAL YITAS++G+SE ELED+LS+DE VLNDVYQYH
Sbjct:  542 MSLPKNVRIIVSTLPNYFSILDTLKRMISEEGNFVIITPLGQDLGSAILRSWLGRANRSITEEQWKIVNEAISKCNLPLFVKLVCDEICRWKSYSKPQLTTLCYTIHDTIIKLFDRIEIQHGKTLVSHALGYITASKSGVSEAELEDLLSLDEKVLNDVYQYH 704          
BLAST of GTPase activator protein vs. TrEMBL
Match: A0A2T7PBM5 (WD_REPEATS_REGION domain-containing protein OS=Pomacea canaliculata OX=400727 GN=C0Q70_10096 PE=4 SV=1)

HSP 1 Score: 142.51 bits (358), Expect = 3.426e-36
Identity = 80/165 (48.48%), Postives = 101/165 (61.21%), Query Frame = 1
Query:    7 FVINFPLRVRIIL-TISNLTIL---------DESKIINIPKLESNISLLIIQQCLNRNCRSLTDVQWDIVKKTIRKCNLPLLVKITFDEISNWSSY-DILKTTLYETIEESIHNLLERIEISHGKILVMHALSYITASRTGISETELEDILSIDEIVLNDVYQYH 468
            F ++ P  V++I  T+ N   L         DES  I +  L  N+S  IIQ  L    R++T  QW IV + I KC+ PL VK+ FDEI  W SY    +T L  TI E+I  L ERIE+ HG+ LV HAL YITAS+ G+SE ELED+LS+D+ VLNDVYQYH
Sbjct:  521 FPVHLPDCVKVIASTLPNYYALLDTLKFMIEDESNFIQVLPLGENLSSTIIQAWLKNENRAVTTEQWAIVNEAISKCSFPLFVKLVFDEICRWRSYTKPSQTVLAFTIHETILRLFERIELQHGRTLVAHALGYITASKDGVSEPELEDLLSLDDKVLNDVYQYH 685          
BLAST of GTPase activator protein vs. Ensembl Cavefish
Match: nwd1 (NACHT and WD repeat domain containing 1 [Source:ZFIN;Acc:ZDB-GENE-071116-8])

HSP 1 Score: 88.9669 bits (219), Expect = 6.009e-21
Identity = 49/115 (42.61%), Postives = 69/115 (60.00%), Query Frame = 1
Query:  121 LIIQQCLNRNCRSLTDVQWDIVKKTIRKCNLPLLVKITFDEISNWSSYDILKTT-LYETIEESIHNLLERIEISHGKILVMHALSYITASRTGISETELEDILSIDEIVLNDVYQ 462
            LI +  +++  R LT  Q D V ++ +K   PL +K+  D    W+SY  L    L  +++E I   L+ +E  HGK+ V HAL YIT SR G+SE EL+DILS+D  VL +VYQ
Sbjct:  176 LITKAYMDKAGRRLTSEQVDAVLQSFQKTGSPLHLKLLLDMAKQWTSYTTLSDIRLGSSVQEVISLFLDSLEGKHGKLFVRHALGYITLSRFGLSEAELQDILSLDNDVLAEVYQ 290          
BLAST of GTPase activator protein vs. Ensembl Cavefish
Match: nwd1 (NACHT and WD repeat domain containing 1 [Source:ZFIN;Acc:ZDB-GENE-071116-8])

HSP 1 Score: 88.9669 bits (219), Expect = 6.185e-21
Identity = 49/115 (42.61%), Postives = 69/115 (60.00%), Query Frame = 1
Query:  121 LIIQQCLNRNCRSLTDVQWDIVKKTIRKCNLPLLVKITFDEISNWSSYDILKTT-LYETIEESIHNLLERIEISHGKILVMHALSYITASRTGISETELEDILSIDEIVLNDVYQ 462
            LI +  +++  R LT  Q D V ++ +K   PL +K+  D    W+SY  L    L  +++E I   L+ +E  HGK+ V HAL YIT SR G+SE EL+DILS+D  VL +VYQ
Sbjct:  506 LITKAYMDKAGRRLTSEQVDAVLQSFQKTGSPLHLKLLLDMAKQWTSYTTLSDIRLGSSVQEVISLFLDSLEGKHGKLFVRHALGYITLSRFGLSEAELQDILSLDNDVLAEVYQ 620          
BLAST of GTPase activator protein vs. Ensembl Cavefish
Match: nwd2 (NACHT and WD repeat domain containing 2 [Source:NCBI gene;Acc:103039682])

HSP 1 Score: 77.7962 bits (190), Expect = 4.843e-17
Identity = 41/102 (40.20%), Postives = 59/102 (57.84%), Query Frame = 1
Query:  154 RSLTDVQWDIVKKTIRKCNLPLLVKITFDEISNWSSY-DILKTTLYETIEESIHNLLERIEISHGKILVMHALSYITASRTGISETELEDILSIDEIVLNDV 456
            R +T  Q   V + + KC LP+ V + + E+ +W S+ D+   +L  T+ ESI  L   IE   G   V  AL Y+T +R G++E ELEDILS+D  VL D+
Sbjct:  582 RKVTSGQQIYVNEALAKCTLPMFVNLIYREVVHWRSHKDVDDKSLCSTVHESIEQLFFSIENKLGSRFVFRALGYVTMARAGLTEVELEDILSLDNSVLGDI 683          
BLAST of GTPase activator protein vs. Ensembl Cavefish
Match: nwd2 (NACHT and WD repeat domain containing 2 [Source:NCBI gene;Acc:103039682])

HSP 1 Score: 77.7962 bits (190), Expect = 4.986e-17
Identity = 41/102 (40.20%), Postives = 59/102 (57.84%), Query Frame = 1
Query:  154 RSLTDVQWDIVKKTIRKCNLPLLVKITFDEISNWSSY-DILKTTLYETIEESIHNLLERIEISHGKILVMHALSYITASRTGISETELEDILSIDEIVLNDV 456
            R +T  Q   V + + KC LP+ V + + E+ +W S+ D+   +L  T+ ESI  L   IE   G   V  AL Y+T +R G++E ELEDILS+D  VL D+
Sbjct:  592 RKVTSGQQIYVNEALAKCTLPMFVNLIYREVVHWRSHKDVDDKSLCSTVHESIEQLFFSIENKLGSRFVFRALGYVTMARAGLTEVELEDILSLDNSVLGDI 693          
BLAST of GTPase activator protein vs. Ensembl Cavefish
Match: nwd2 (NACHT and WD repeat domain containing 2 [Source:NCBI gene;Acc:103039682])

HSP 1 Score: 77.7962 bits (190), Expect = 5.096e-17
Identity = 41/102 (40.20%), Postives = 59/102 (57.84%), Query Frame = 1
Query:  154 RSLTDVQWDIVKKTIRKCNLPLLVKITFDEISNWSSY-DILKTTLYETIEESIHNLLERIEISHGKILVMHALSYITASRTGISETELEDILSIDEIVLNDV 456
            R +T  Q   V + + KC LP+ V + + E+ +W S+ D+   +L  T+ ESI  L   IE   G   V  AL Y+T +R G++E ELEDILS+D  VL D+
Sbjct:  669 RKVTSGQQIYVNEALAKCTLPMFVNLIYREVVHWRSHKDVDDKSLCSTVHESIEQLFFSIENKLGSRFVFRALGYVTMARAGLTEVELEDILSLDNSVLGDI 770          
BLAST of GTPase activator protein vs. Ensembl Nematostella
Match: EDO37261 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SG70])

HSP 1 Score: 121.324 bits (303), Expect = 7.981e-33
Identity = 61/128 (47.66%), Postives = 88/128 (68.75%), Query Frame = 1
Query:   85 INIPKLESNISLLIIQQCLNRNCRSLTDVQWDIVKKTIRKCNLPLLVKITFDEISNWSSY-DILKTTLYETIEESIHNLLERIEISHGKILVMHALSYITASRTGISETELEDILSIDEIVLNDVYQY 465
            I++P L  +    I+   L ++ R+L   Q D+V     +C LPL +KI+FDE   W SY D  +T LY ++ ++I+ LLERIE  HG+ILV HAL Y+TA+R+G++ETEL+DILS D+ VL+DV+QY
Sbjct:  462 ISVPSLPHSDVSDILSMWLQQSGRTLQPAQRDLVMSAFSQCPLPLFLKISFDEACRWHSYTDPGQTRLYGSVRDAINGLLERIEAKHGRILVQHALGYLTAARSGLTETELDDILSSDDEVLDDVFQY 589          
BLAST of GTPase activator protein vs. Ensembl Nematostella
Match: EDO34994 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SMT6])

HSP 1 Score: 115.546 bits (288), Expect = 9.856e-31
Identity = 56/126 (44.44%), Postives = 86/126 (68.25%), Query Frame = 1
Query:   91 IPKLESNISLLIIQQCLNRNCRSLTDVQWDIVKKTIRKCNLPLLVKITFDEISNWSSYDIL-KTTLYETIEESIHNLLERIEISHGKILVMHALSYITASRTGISETELEDILSIDEIVLNDVYQY 465
            +PKL    +  I+   L    R+L+  Q DIV++ +++C+LP+ V++ FDE   W SY  L +T L  T+  +I++L ER+E  HG +LV  AL Y+TA+++G++ETELED+LS D+ VL+DVYQY
Sbjct:  473 VPKLPQKDAAEILVSYLRMEHRTLSTDQQDIVQQALQECSLPIFVRVAFDEAIRWKSYSPLDETVLQHTVRGAINSLFERVERQHGHVLVSRALGYVTAAKSGLTETELEDLLSCDDFVLDDVYQY 598          
BLAST of GTPase activator protein vs. Ensembl Nematostella
Match: EDO40517 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S6Z9])

HSP 1 Score: 108.997 bits (271), Expect = 2.178e-28
Identity = 56/135 (41.48%), Postives = 84/135 (62.22%), Query Frame = 1
Query:   64 ILDESKIINIPKLESNISLLIIQQCLNRNCRSLTDVQWDIVKKTIRKCNLPLLVKITFDEISNWSSYDIL-KTTLYETIEESIHNLLERIEISHGKILVMHALSYITASRTGISETELEDILSIDEIVLNDVYQY 465
            +LD +  + +  L S ++  I+   L+ + R LTD Q  IV     +C LPL +++ +D    W SY  L K+ L + ++  I  L +R+E  HG +LV HAL+YITA++ G+SE ELEDILS DE VL++V+QY
Sbjct:  470 LLDSNCFVEVSSLPSEVACNILTSWLSNDNRRLTDSQRKIVLNAFNRCPLPLYLRLAYDHAVTWKSYTPLEKSVLEKNVQGMIKALFKRLERRHGTVLVRHALAYITAAKHGLSEPELEDILSCDEEVLDEVFQY 604          
BLAST of GTPase activator protein vs. Ensembl Nematostella
Match: EDO31117 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SYV4])

HSP 1 Score: 108.612 bits (270), Expect = 3.508e-28
Identity = 58/143 (40.56%), Postives = 85/143 (59.44%), Query Frame = 1
Query:   40 ILTISNLTILDESKIINIPKLESNISLLIIQQCLNRNCRSLTDVQWDIVKKTIRKCNLPLLVKITFDEISNWSSY-DILKTTLYETIEESIHNLLERIEISHGKILVMHALSYITASRTGISETELEDILSIDEIVLNDVYQY 465
            IL     ++ D +  I +P L  +    I+   L+   R+LT  Q  +V     KC  PL +K+ F E S W+SY D+   +L   + E+I  L ER+E  HGK+L   AL Y+TA+R+G++E ELEDILS+D+ V++DVYQY
Sbjct:  506 ILPTLQRSLTDTNCYIEVPTLSRDTGHEILDAWLDSKHRTLTPEQRVLVMAAFDKCPQPLFLKLIFAEASEWASYTDVSGVSLGANVPEAIGFLFERLERKHGKMLFSRALQYVTAARSGLTENELEDILSLDDDVIDDVYQY 648          
BLAST of GTPase activator protein vs. Ensembl Nematostella
Match: EDO47107 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RNA8])

HSP 1 Score: 77.7962 bits (190), Expect = 1.558e-17
Identity = 54/129 (41.86%), Postives = 81/129 (62.79%), Query Frame = 1
Query:   82 IINIPKLESNISLLIIQQCLNRNCRSLTDVQWDIVKKTIRKCNLPLLVKITFDEISNWSSYDILKTT-LYETIEESIHNLLERIEISHGKILVMHALSYITASRTGISETELEDILSIDEIVLNDVYQY 465
            ++ +P++  + + LI+   L    R+L   Q + V  + ++C LPL +K+ FDE   W SY  ++   L   I + I  L +R+E  HGK LV H+L YITAS+ G++E ELED+LS+D+ VLNDVYQY
Sbjct:  459 LMEVPQIPMSEAGLILDNWLKAANRALQPAQRNEVMISFKECPLPLYLKLAFDESCRWKSYTPMQDADLAPNITDIIRALFDRVERIHGKTLVSHSLGYITASKNGLTEPELEDLLSLDDDVLNDVYQY 587          
BLAST of GTPase activator protein vs. Ensembl Medaka
Match: nwd2 (NACHT and WD repeat domain containing 2 [Source:NCBI gene;Acc:101165765])

HSP 1 Score: 81.2629 bits (199), Expect = 3.165e-18
Identity = 46/115 (40.00%), Postives = 67/115 (58.26%), Query Frame = 1
Query:  115 SLLIIQQCLNRNCRSLTDVQWDIVKKTIRKCNLPLLVKITFDEISNWSSY-DILKTTLYETIEESIHNLLERIEISHGKILVMHALSYITASRTGISETELEDILSIDEIVLNDV 456
            S ++ QQ L    R +T  Q   V + + KC LP+ V + + E+ +W S+ D+   +L  T+ ESI  L   +E   G+  V  AL YIT ++ G++E ELEDILS+D IVL DV
Sbjct:  570 SQMLKQQLLGVK-RKVTSGQQIYVNEALAKCTLPMFVNLIYREVVHWRSHKDVDDKSLCSTVHESIEQLFYSVENKLGQRFVFRALGYITMAKAGLTEVELEDILSLDNIVLGDV 683          
BLAST of GTPase activator protein vs. Ensembl Medaka
Match: nwd2 (NACHT and WD repeat domain containing 2 [Source:NCBI gene;Acc:101165765])

HSP 1 Score: 81.2629 bits (199), Expect = 3.419e-18
Identity = 46/115 (40.00%), Postives = 67/115 (58.26%), Query Frame = 1
Query:  115 SLLIIQQCLNRNCRSLTDVQWDIVKKTIRKCNLPLLVKITFDEISNWSSY-DILKTTLYETIEESIHNLLERIEISHGKILVMHALSYITASRTGISETELEDILSIDEIVLNDV 456
            S ++ QQ L    R +T  Q   V + + KC LP+ V + + E+ +W S+ D+   +L  T+ ESI  L   +E   G+  V  AL YIT ++ G++E ELEDILS+D IVL DV
Sbjct:  580 SQMLKQQLLGVK-RKVTSGQQIYVNEALAKCTLPMFVNLIYREVVHWRSHKDVDDKSLCSTVHESIEQLFYSVENKLGQRFVFRALGYITMAKAGLTEVELEDILSLDNIVLGDV 693          
BLAST of GTPase activator protein vs. Ensembl Medaka
Match: nwd2 (NACHT and WD repeat domain containing 2 [Source:NCBI gene;Acc:101165765])

HSP 1 Score: 81.2629 bits (199), Expect = 3.419e-18
Identity = 46/115 (40.00%), Postives = 67/115 (58.26%), Query Frame = 1
Query:  115 SLLIIQQCLNRNCRSLTDVQWDIVKKTIRKCNLPLLVKITFDEISNWSSY-DILKTTLYETIEESIHNLLERIEISHGKILVMHALSYITASRTGISETELEDILSIDEIVLNDV 456
            S ++ QQ L    R +T  Q   V + + KC LP+ V + + E+ +W S+ D+   +L  T+ ESI  L   +E   G+  V  AL YIT ++ G++E ELEDILS+D IVL DV
Sbjct:  580 SQMLKQQLLGVK-RKVTSGQQIYVNEALAKCTLPMFVNLIYREVVHWRSHKDVDDKSLCSTVHESIEQLFYSVENKLGQRFVFRALGYITMAKAGLTEVELEDILSLDNIVLGDV 693          
BLAST of GTPase activator protein vs. Ensembl Medaka
Match: nwd1 (NACHT and WD repeat domain containing 1 [Source:ZFIN;Acc:ZDB-GENE-071116-8])

HSP 1 Score: 75.0998 bits (183), Expect = 3.929e-16
Identity = 47/160 (29.38%), Postives = 83/160 (51.88%), Query Frame = 1
Query:   16 NFPLRVRIILTIS-------NLTILDES--KIINIPKLESNISLLIIQQCLNRNCRSLTDVQWDIVKKTIRKCNLPLLVKITFDEISNWSSYDILKTTLY-ETIEESIHNLLERIEISHGKILVMHALSYITASRTGISETELEDILSIDEIVLNDVYQY 465
            N P +V +++++        N+ +  +S      + +L  +    I++  L  + R+LT  Q D+  ++      PL +K+    + NW+S+  L   L     EE +  LL R+E  H K LV  AL YI  +R G+ E EL D++S+D+ V+++VY+Y
Sbjct:  463 NLPPKVHLLVSMDTCSEAFVNMRLKTDSLENFFEVERLSRDEGERIMESHLRASQRTLTAEQKDVALQSFTLTGCPLHLKLILSAVQNWTSFTPLTEQLLGNNTEEVMSQLLHRLEHKHRKELVGGALGYIALARDGLLEAELYDVMSLDDDVISEVYRY 622          
BLAST of GTPase activator protein vs. Ensembl Medaka
Match: ENSORLT00000012836.2 (NACHT and WD repeat domain-containing protein 2 [Source:NCBI gene;Acc:101161570])

HSP 1 Score: 64.3142 bits (155), Expect = 2.520e-12
Identity = 32/93 (34.41%), Postives = 55/93 (59.14%), Query Frame = 1
Query:  154 RSLTDVQWDIVKKTIRKCNLPLLVKITFDEISNWSS-YDILKTTLYETIEESIHNLLERIEISHGKILVMHALSYITASRTGISETELEDILS 429
            R +T  Q  ++ + +  C LPL  ++     + WSS  ++ ++ L + +  SI  LL+ +E+ HG  LV  A S++T S++G+SE EL D+LS
Sbjct:  586 RRVTSGQQALINEALTSCRLPLYTRLLHVHAAGWSSDSEVNESFLPDGVHSSISALLDHLELKHGSALVARATSFLTLSKSGLSEAELADLLS 678          
BLAST of GTPase activator protein vs. Planmine SMEST
Match: SMESG000018097.1 (SMESG000018097.1)

HSP 1 Score: 306.99 bits (785), Expect = 1.455e-97
Identity = 154/156 (98.72%), Postives = 155/156 (99.36%), Query Frame = 1
Query:    1 GNFVINFPLRVRIILTISNLTILDESKIINIPKLESNISLLIIQQCLNRNCRSLTDVQWDIVKKTIRKCNLPLLVKITFDEISNWSSYDILKTTLYETIEESIHNLLERIEISHGKILVMHALSYITASRTGISETELEDILSIDEIVLNDVYQYH 468
            GNFVINFPLRVRIILTISNLTILDESKIINIPKLESNISLLIIQQCLNRNCRSLTDVQW IVKKT+RKCNLPLLVKITFDEISNWSSYDILKTTLYETIEESIHNLLERIEISHGKILVMHALSYITASRTGISETELEDILSIDEIVLNDVYQYH
Sbjct:  189 GNFVINFPLRVRIILTISNLTILDESKIINIPKLESNISLLIIQQCLNRNCRSLTDVQWGIVKKTLRKCNLPLLVKITFDEISNWSSYDILKTTLYETIEESIHNLLERIEISHGKILVMHALSYITASRTGISETELEDILSIDEIVLNDVYQYH 344          
BLAST of GTPase activator protein vs. Planmine SMEST
Match: SMESG000018097.1 (SMESG000018097.1)

HSP 1 Score: 305.834 bits (782), Expect = 7.636e-97
Identity = 154/156 (98.72%), Postives = 155/156 (99.36%), Query Frame = 1
Query:    1 GNFVINFPLRVRIILTISNLTILDESKIINIPKLESNISLLIIQQCLNRNCRSLTDVQWDIVKKTIRKCNLPLLVKITFDEISNWSSYDILKTTLYETIEESIHNLLERIEISHGKILVMHALSYITASRTGISETELEDILSIDEIVLNDVYQYH 468
            GNFVINFPLRVRIILTISNLTILDESKIINIPKLESNISLLIIQQCLNRNCRSLTDVQW IVKKT+RKCNLPLLVKITFDEISNWSSYDILKTTLYETIEESIHNLLERIEISHGKILVMHALSYITASRTGISETELEDILSIDEIVLNDVYQYH
Sbjct:  442 GNFVINFPLRVRIILTISNLTILDESKIINIPKLESNISLLIIQQCLNRNCRSLTDVQWGIVKKTLRKCNLPLLVKITFDEISNWSSYDILKTTLYETIEESIHNLLERIEISHGKILVMHALSYITASRTGISETELEDILSIDEIVLNDVYQYH 597          
BLAST of GTPase activator protein vs. Planmine SMEST
Match: SMESG000074035.1 (SMESG000074035.1)

HSP 1 Score: 73.9442 bits (180), Expect = 7.006e-16
Identity = 42/133 (31.58%), Postives = 75/133 (56.39%), Query Frame = 1
Query:   73 ESKIINIPKLESNISLLIIQQCLNRNCRSLTDVQWDIVKKTIRKCNLPLLVKITFDEISNWSSY-DILKTTLYETIEESIHNLLERIEISHGKILVMHALSYITASRTGISETELEDILSIDEIVLNDVYQYH 468
            + K I+I   +    +LI Q  L    R+LTD+Q +++   +      L +K+  ++   W SY  + +  + + +E +++     +E  +G +L+ HAL Y+T    G++E ELED+LS+ + VLN+VYQYH
Sbjct:  581 QHKFIHINYFDDKEVVLICQSLLEHKKRTLTDLQMNLIISKLINNPRGLYIKLALEQAVTWKSYMSMEECIIKDCVESAVNFKFACLEEKYGLLLMSHALGYLTLGYNGLTEIELEDLLSLQDNVLNEVYQYH 713          
BLAST of GTPase activator protein vs. Planmine SMEST
Match: SMESG000074035.1 (SMESG000074035.1)

HSP 1 Score: 73.9442 bits (180), Expect = 7.059e-16
Identity = 42/133 (31.58%), Postives = 75/133 (56.39%), Query Frame = 1
Query:   73 ESKIINIPKLESNISLLIIQQCLNRNCRSLTDVQWDIVKKTIRKCNLPLLVKITFDEISNWSSY-DILKTTLYETIEESIHNLLERIEISHGKILVMHALSYITASRTGISETELEDILSIDEIVLNDVYQYH 468
            + K I+I   +    +LI Q  L    R+LTD+Q +++   +      L +K+  ++   W SY  + +  + + +E +++     +E  +G +L+ HAL Y+T    G++E ELED+LS+ + VLN+VYQYH
Sbjct:  581 QHKFIHINYFDDKEVVLICQSLLEHKKRTLTDLQMNLIISKLINNPRGLYIKLALEQAVTWKSYMSMEECIIKDCVESAVNFKFACLEEKYGLLLMSHALGYLTLGYNGLTEIELEDLLSLQDNVLNEVYQYH 713          
BLAST of GTPase activator protein vs. Planmine SMEST
Match: SMESG000074035.1 (SMESG000074035.1)

HSP 1 Score: 73.9442 bits (180), Expect = 7.305e-16
Identity = 42/133 (31.58%), Postives = 75/133 (56.39%), Query Frame = 1
Query:   73 ESKIINIPKLESNISLLIIQQCLNRNCRSLTDVQWDIVKKTIRKCNLPLLVKITFDEISNWSSY-DILKTTLYETIEESIHNLLERIEISHGKILVMHALSYITASRTGISETELEDILSIDEIVLNDVYQYH 468
            + K I+I   +    +LI Q  L    R+LTD+Q +++   +      L +K+  ++   W SY  + +  + + +E +++     +E  +G +L+ HAL Y+T    G++E ELED+LS+ + VLN+VYQYH
Sbjct:  610 QHKFIHINYFDDKEVVLICQSLLEHKKRTLTDLQMNLIISKLINNPRGLYIKLALEQAVTWKSYMSMEECIIKDCVESAVNFKFACLEEKYGLLLMSHALGYLTLGYNGLTEIELEDLLSLQDNVLNEVYQYH 742          
The following BLAST results are available for this feature:
BLAST of GTPase activator protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
NWD11.225e-2334.38NACHT and WD repeat domain containing 1 [Source:HG... [more]
NWD11.225e-2334.38NACHT and WD repeat domain containing 1 [Source:HG... [more]
NWD11.225e-2334.38NACHT and WD repeat domain containing 1 [Source:HG... [more]
NWD11.230e-2334.38NACHT and WD repeat domain containing 1 [Source:HG... [more]
NWD11.232e-2334.38NACHT and WD repeat domain containing 1 [Source:HG... [more]
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BLAST of GTPase activator protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 1
Match NameE-valueIdentityDescription
T05C3.21.116e-3441.18pep chromosome:WBcel235:V:5493747:5503010:1 gene:W... [more]
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BLAST of GTPase activator protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 1
Match NameE-valueIdentityDescription
CG101851.851e-3546.62gene:FBgn0038397 transcript:FBtr0083235[more]
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BLAST of GTPase activator protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 4
Match NameE-valueIdentityDescription
nwd19.141e-1935.90NACHT and WD repeat domain containing 1 [Source:ZF... [more]
nwd22.693e-1732.70NACHT and WD repeat domain containing 2 [Source:ZF... [more]
CU570791.31.776e-1236.36NACHT and WD repeat domain-containing protein 2-li... [more]
si:ch211-212k18.61.616e-625.38si:ch211-212k18.6 [Source:ZFIN;Acc:ZDB-GENE-130530... [more]
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BLAST of GTPase activator protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 4
Match NameE-valueIdentityDescription
ppp1r3c.11.232e-2739.87protein phosphatase 1, regulatory (inhibitor) subu... [more]
hsp90ab15.461e-1835.63heat shock protein 90kDa alpha family class B memb... [more]
ENSXETT00000022477.11.466e-1233.63pep primary_assembly:Xenopus_tropicalis_v9.1:KV460... [more]
ENSXETT00000003639.12.319e-731.03uncharacterized LOC101730828 [Source:NCBI gene;Acc... [more]
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BLAST of GTPase activator protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 4
Match NameE-valueIdentityDescription
Nwd14.480e-2135.26NACHT and WD repeat domain containing 1 [Source:MG... [more]
Nwd14.488e-2135.26NACHT and WD repeat domain containing 1 [Source:MG... [more]
Nwd14.488e-2135.26NACHT and WD repeat domain containing 1 [Source:MG... [more]
Nwd25.368e-1838.21NACHT and WD repeat domain containing 2 [Source:MG... [more]
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BLAST of GTPase activator protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 4
Match NameE-valueIdentityDescription
sp|Q149M9|NWD1_HUMAN5.918e-2334.38NACHT domain- and WD repeat-containing protein 1 O... [more]
sp|A6H603|NWD1_MOUSE3.139e-2035.26NACHT domain- and WD repeat-containing protein 1 O... [more]
sp|Q6P5U7|NWD2_MOUSE3.755e-1738.21NACHT and WD repeat domain-containing protein 2 OS... [more]
sp|Q9ULI1|NWD2_HUMAN1.207e-1637.40NACHT and WD repeat domain-containing protein 2 OS... [more]
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BLAST of GTPase activator protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
R7U0H52.094e-4152.94Uncharacterized protein (Fragment) OS=Capitella te... [more]
R7TPK77.262e-3852.94Uncharacterized protein OS=Capitella teleta OX=283... [more]
A0A210PU693.803e-3750.00Uncharacterized protein OS=Mizuhopecten yessoensis... [more]
A0A1S3KFF11.314e-3650.31NACHT and WD repeat domain-containing protein 2 OS... [more]
A0A2T7PBM53.426e-3648.48WD_REPEATS_REGION domain-containing protein OS=Pom... [more]
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BLAST of GTPase activator protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
nwd16.009e-2142.61NACHT and WD repeat domain containing 1 [Source:ZF... [more]
nwd16.185e-2142.61NACHT and WD repeat domain containing 1 [Source:ZF... [more]
nwd24.843e-1740.20NACHT and WD repeat domain containing 2 [Source:NC... [more]
nwd24.986e-1740.20NACHT and WD repeat domain containing 2 [Source:NC... [more]
nwd25.096e-1740.20NACHT and WD repeat domain containing 2 [Source:NC... [more]
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BLAST of GTPase activator protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of GTPase activator protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of GTPase activator protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO372617.981e-3347.66Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO349949.856e-3144.44Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO405172.178e-2841.48Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO311173.508e-2840.56Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO471071.558e-1741.86Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of GTPase activator protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
nwd23.165e-1840.00NACHT and WD repeat domain containing 2 [Source:NC... [more]
nwd23.419e-1840.00NACHT and WD repeat domain containing 2 [Source:NC... [more]
nwd23.419e-1840.00NACHT and WD repeat domain containing 2 [Source:NC... [more]
nwd13.929e-1629.38NACHT and WD repeat domain containing 1 [Source:ZF... [more]
ENSORLT00000012836.22.520e-1234.41NACHT and WD repeat domain-containing protein 2 [S... [more]
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BLAST of GTPase activator protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000018097.11.455e-9798.72SMESG000018097.1[more]
SMESG000018097.17.636e-9798.72SMESG000018097.1[more]
SMESG000074035.17.006e-1631.58SMESG000074035.1[more]
SMESG000074035.17.059e-1631.58SMESG000074035.1[more]
SMESG000074035.17.305e-1631.58SMESG000074035.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30028597 ID=SMED30028597|Name=GTPase activator protein|organism=Schmidtea mediterranea sexual|type=transcript|length=470bp
GGAAACTTTGTCATTAATTTCCCATTACGTGTTAGAATCATTTTAACTAT
CTCAAATCTAACTATATTGGATGAATCAAAAATCATAAACATTCCAAAAC
TGGAGTCAAACATCTCTTTATTAATTATTCAACAGTGTTTAAACAGAAAT
TGCCGGAGTTTGACAGATGTTCAATGGGACATTGTTAAGAAGACAATAAG
AAAATGTAATCTCCCATTGCTAGTTAAAATAACTTTTGATGAAATATCAA
ATTGGTCTTCATATGACATATTAAAGACAACATTATATGAAACAATTGAA
GAGAGTATTCATAACCTGCTTGAAAGAATTGAAATTTCTCACGGGAAAAT
ATTGGTAATGCATGCTCTATCTTACATAACAGCTTCTAGGACGGGAATTT
CTGAAACAGAATTGGAGGATATTTTATCTATTGACGAAATTGTGCTTAAT
GATGTTTACCAATATCATTT
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protein sequence of SMED30028597-orf-1

>SMED30028597-orf-1 ID=SMED30028597-orf-1|Name=SMED30028597-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=156bp
GNFVINFPLRVRIILTISNLTILDESKIINIPKLESNISLLIIQQCLNRN
CRSLTDVQWDIVKKTIRKCNLPLLVKITFDEISNWSSYDILKTTLYETIE
ESIHNLLERIEISHGKILVMHALSYITASRTGISETELEDILSIDEIVLN
DVYQYH
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: molecular function
TermDefinition
GO:0003700transcription factor activity, sequence-specific DNA binding
GO:0000166nucleotide binding
GO:0005524ATP binding
Vocabulary: biological process
TermDefinition
GO:0006355regulation of transcription, DNA-templated
GO:0008380RNA splicing
Vocabulary: cellular component
TermDefinition
GO:0005682U5 snRNP
GO:0005737cytoplasm
GO:0005829cytosol
GO:0071011precatalytic spliceosome
GO:0071013catalytic step 2 spliceosome
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
NoneNo IPR availablePANTHERPTHR19871BETA TRANSDUCIN-RELATED PROTEINcoord: 6..156