Protein kinase

Overview
NameProtein kinase
Smed IDSMED30028591
Length (bp)3499
Neoblast Clusters

Zeng et. al., 2018




▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 



 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)




Explore this single cell expression dataset with our NB Cluster Shiny App




 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Protein kinase (SMED30028591) t-SNE clustered cells

Violin plots show distribution of expression levels for Protein kinase (SMED30028591) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Protein kinase (SMED30028591) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Protein kinase (SMED30028591) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017




Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020




SMED30028591

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 10

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
pharynxSMED30028591h1SMcG0007287 dd_Smed_v4_11177_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
protonephridiaSMED30028591h1SMcG0007287 dd_Smed_v4_11177_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
nervous systemSMED30028591h1SMcG0007287 dd_Smed_v4_11177_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30028591h1SMcG0007287 dd_Smed_v4_11177_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
muscle cellSMED30028591h1SMcG0007287 dd_Smed_v4_11177_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
non-ciliated neuronSMED30028591h1SMcG0007287 dd_Smed_v4_11177_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
photoreceptor neuronSMED30028591h1SMcG0007287 SMED30028591smed_20140614PMID:22884275
Lapan et al., 2012
whole organism asexual adult colorimetric in situ hybridization evidence
pigment cellSMED30028591h1SMcG0007287 SMED30028591smed_20140614PMID:22884275
Lapan et al., 2012
whole organism asexual adult colorimetric in situ hybridization evidence
reproductive organSMED30028591h1SMcG0007287 Contig48368uc_Smed_v2PMID:28434803
Rouhana et al., 2017
whole organism adult hermaphrodite RNA-sequencing evidence
reproductive organSMED30028591h1SMcG0007287 Contig48368newmark_estsPMID:28434803
Rouhana et al., 2017
whole organism adult hermaphrodite RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
BLAST of Protein kinase vs. Ensembl Human
Match: TTBK2 (tau tubulin kinase 2 [Source:HGNC Symbol;Acc:HGNC:19141])

HSP 1 Score: 407.142 bits (1045), Expect = 6.800e-130
Identity = 186/304 (61.18%), Postives = 230/304 (75.66%), Query Frame = 3
Query:   27 MPSTKQETDLLNPSNIVKDRWKVIRKLGGGGFGEIYECLDSHTQEKVALKLESSRIAKQVLKMEVAVLKKLQGTAHVCKFLGCGRNDRFNYVAMTLQGKNLADLRRAQKNSAFSISTMLRLSAQILQSIQDIHNSGFLHRDIKPSNFSMGRLPLSSHTVVMLDFGLARQYILPDGNGDIRAPRPVTGFRGTVRYASVNAHMNREMGRHDDLWSAFYMMAEMVTGSLPWRKLKDKDQVGQIKQNFEHTQLLRHLPSEFKLLLSHIQSLTYFDAPDYEYLKNLIYQCMRRKGISSDELFDWETTSD 938
            M    ++ D+L+   +VK+RWKV+RK+GGGGFGEIY+ LD  T+E VALK+ES++  KQVLKMEVAVLKKLQG  HVC+F+GCGRNDRFNYV M LQG+NLADLRR+Q    F+IST LRL  QIL+SI+ IH+ GFLHRDIKPSNF+MGR P +     MLDFGLARQ+   +  GD+R PR V GFRGTVRYAS+NAH NREMGRHDDLWS FYM+ E V G LPWRK+KDK+QVG IK+ ++H  +L+HLP EF + L HI SL YF  PDY+ L ++    ++  G+   + FDWE T +
Sbjct:    1 MSGGGEQLDILSVGILVKERWKVLRKIGGGGFGEIYDALDMLTRENVALKVESAQQPKQVLKMEVAVLKKLQGKDHVCRFIGCGRNDRFNYVVMQLQGRNLADLRRSQSRGTFTISTTLRLGRQILESIESIHSVGFLHRDIKPSNFAMGRFPSTCRKCYMLDFGLARQFT--NSCGDVRPPRAVAGFRGTVRYASINAHRNREMGRHDDLWSLFYMLVEFVVGQLPWRKIKDKEQVGSIKERYDHRLMLKHLPPEFSIFLDHISSLDYFTKPDYQLLTSVFDNSIKTFGVIESDPFDWEKTGN 302          
BLAST of Protein kinase vs. Ensembl Human
Match: TTBK1 (tau tubulin kinase 1 [Source:HGNC Symbol;Acc:HGNC:19140])

HSP 1 Score: 425.631 bits (1093), Expect = 7.451e-128
Identity = 188/295 (63.73%), Postives = 231/295 (78.31%), Query Frame = 3
Query:   42 QETDLLNPSNIVKDRWKVIRKLGGGGFGEIYECLDSHTQEKVALKLESSRIAKQVLKMEVAVLKKLQGTAHVCKFLGCGRNDRFNYVAMTLQGKNLADLRRAQKNSAFSISTMLRLSAQILQSIQDIHNSGFLHRDIKPSNFSMGRLPLSSHTVVMLDFGLARQYILPDGNGDIRAPRPVTGFRGTVRYASVNAHMNREMGRHDDLWSAFYMMAEMVTGSLPWRKLKDKDQVGQIKQNFEHTQLLRHLPSEFKLLLSHIQSLTYFDAPDYEYLKNLIYQCMRRKGISSDELFDWE 926
            ++ D+L  + +VKDRWKV++K+GGGGFGEIYE +D  T+E VALK+ES++  KQVLKMEVAVLKKLQG  HVC+F+GCGRN++FNYV M LQG+NLADLRR+Q    F++ST LRL  QIL+SI+ IH+ GFLHRDIKPSNF+MGRLP +     MLDFGLARQY   +  GD+R PR V GFRGTVRYASVNAH NREMGRHDDLWS FYM+ E   G LPWRK+KDK+QVG IK+ +EH  LL+H+PSEF L L HI SL YF  PDY+ + ++    M+ +GI+ +E FDWE
Sbjct:   19 EQADILPANYVVKDRWKVLKKIGGGGFGEIYEAMDLLTRENVALKVESAQQPKQVLKMEVAVLKKLQGKDHVCRFIGCGRNEKFNYVVMQLQGRNLADLRRSQPRGTFTLSTTLRLGKQILESIEAIHSVGFLHRDIKPSNFAMGRLPSTYRKCYMLDFGLARQYT--NTTGDVRPPRNVAGFRGTVRYASVNAHKNREMGRHDDLWSLFYMLVEFAVGQLPWRKIKDKEQVGMIKEKYEHRMLLKHMPSEFHLFLDHIASLDYFTKPDYQLIMSVFENSMKERGIAENEAFDWE 311          
BLAST of Protein kinase vs. Ensembl Human
Match: TTBK2 (tau tubulin kinase 2 [Source:HGNC Symbol;Acc:HGNC:19141])

HSP 1 Score: 412.149 bits (1058), Expect = 1.630e-123
Identity = 186/304 (61.18%), Postives = 230/304 (75.66%), Query Frame = 3
Query:   27 MPSTKQETDLLNPSNIVKDRWKVIRKLGGGGFGEIYECLDSHTQEKVALKLESSRIAKQVLKMEVAVLKKLQGTAHVCKFLGCGRNDRFNYVAMTLQGKNLADLRRAQKNSAFSISTMLRLSAQILQSIQDIHNSGFLHRDIKPSNFSMGRLPLSSHTVVMLDFGLARQYILPDGNGDIRAPRPVTGFRGTVRYASVNAHMNREMGRHDDLWSAFYMMAEMVTGSLPWRKLKDKDQVGQIKQNFEHTQLLRHLPSEFKLLLSHIQSLTYFDAPDYEYLKNLIYQCMRRKGISSDELFDWETTSD 938
            M    ++ D+L+   +VK+RWKV+RK+GGGGFGEIY+ LD  T+E VALK+ES++  KQVLKMEVAVLKKLQG  HVC+F+GCGRNDRFNYV M LQG+NLADLRR+Q    F+IST LRL  QIL+SI+ IH+ GFLHRDIKPSNF+MGR P +     MLDFGLARQ+   +  GD+R PR V GFRGTVRYAS+NAH NREMGRHDDLWS FYM+ E V G LPWRK+KDK+QVG IK+ ++H  +L+HLP EF + L HI SL YF  PDY+ L ++    ++  G+   + FDWE T +
Sbjct:    1 MSGGGEQLDILSVGILVKERWKVLRKIGGGGFGEIYDALDMLTRENVALKVESAQQPKQVLKMEVAVLKKLQGKDHVCRFIGCGRNDRFNYVVMQLQGRNLADLRRSQSRGTFTISTTLRLGRQILESIESIHSVGFLHRDIKPSNFAMGRFPSTCRKCYMLDFGLARQFT--NSCGDVRPPRAVAGFRGTVRYASINAHRNREMGRHDDLWSLFYMLVEFVVGQLPWRKIKDKEQVGSIKERYDHRLMLKHLPPEFSIFLDHISSLDYFTKPDYQLLTSVFDNSIKTFGVIESDPFDWEKTGN 302          
BLAST of Protein kinase vs. Ensembl Human
Match: TTBK1 (tau tubulin kinase 1 [Source:HGNC Symbol;Acc:HGNC:19140])

HSP 1 Score: 371.703 bits (953), Expect = 1.380e-113
Identity = 168/262 (64.12%), Postives = 203/262 (77.48%), Query Frame = 3
Query:  141 LDSHTQEKVALKLESSRIAKQVLKMEVAVLKKLQGTAHVCKFLGCGRNDRFNYVAMTLQGKNLADLRRAQKNSAFSISTMLRLSAQILQSIQDIHNSGFLHRDIKPSNFSMGRLPLSSHTVVMLDFGLARQYILPDGNGDIRAPRPVTGFRGTVRYASVNAHMNREMGRHDDLWSAFYMMAEMVTGSLPWRKLKDKDQVGQIKQNFEHTQLLRHLPSEFKLLLSHIQSLTYFDAPDYEYLKNLIYQCMRRKGISSDELFDWE 926
            +D  T+E VALK+ES++  KQVLKMEVAVLKKLQG  HVC+F+GCGRN++FNYV M LQG+NLADLRR+Q    F++ST LRL  QIL+SI+ IH+ GFLHRDIKPSNF+MGRLP +     MLDFGLARQY   +  GD+R PR V GFRGTVRYASVNAH NREMGRHDDLWS FYM+ E   G LPWRK+KDK+QVG IK+ +EH  LL+H+PSEF L L HI SL YF  PDY+ + ++    M+ +GI+ +E FDWE
Sbjct:    1 MDLLTRENVALKVESAQQPKQVLKMEVAVLKKLQGKDHVCRFIGCGRNEKFNYVVMQLQGRNLADLRRSQPRGTFTLSTTLRLGKQILESIEAIHSVGFLHRDIKPSNFAMGRLPSTYRKCYMLDFGLARQYT--NTTGDVRPPRNVAGFRGTVRYASVNAHKNREMGRHDDLWSLFYMLVEFAVGQLPWRKIKDKEQVGMIKEKYEHRMLLKHMPSEFHLFLDHIASLDYFTKPDYQLIMSVFENSMKERGIAENEAFDWE 260          
BLAST of Protein kinase vs. Ensembl Human
Match: TTBK2 (tau tubulin kinase 2 [Source:HGNC Symbol;Acc:HGNC:19141])

HSP 1 Score: 352.058 bits (902), Expect = 1.218e-109
Identity = 167/304 (54.93%), Postives = 206/304 (67.76%), Query Frame = 3
Query:   27 MPSTKQETDLLNPSNIVKDRWKVIRKLGGGGFGEIYECLDSHTQEKVALKLESSRIAKQVLKMEVAVLKKLQGTAHVCKFLGCGRNDRFNYVAMTLQGKNLADLRRAQKNSAFSISTMLRLSAQILQSIQDIHNSGFLHRDIKPSNFSMGRLPLSSHTVVMLDFGLARQYILPDGNGDIRAPRPVTGFRGTVRYASVNAHMNREMGRHDDLWSAFYMMAEMVTGSLPWRKLKDKDQVGQIKQNFEHTQLLRHLPSEFKLLLSHIQSLTYFDAPDYEYLKNLIYQCMRRKGISSDELFDWETTSD 938
            M    ++ D+L+   +VK+RWKV+RK+GGGGFGEIY+ LD  T+E VALK+ES++  KQVLKMEVAVLKKLQG  HVC+F+GCGRNDRFNYV M LQG+NLADLRR+Q    F+IST LRL  QIL+SI+ IH+ GFLHRDIKP                                     PR V GFRGTVRYAS+NAH NREMGRHDDLWS FYM+ E V G LPWRK+KDK+QVG IK+ ++H  +L+HLP EF + L HI SL YF  PDY+ L ++    ++  G+   + FDWE T +
Sbjct:    1 MSGGGEQLDILSVGILVKERWKVLRKIGGGGFGEIYDALDMLTRENVALKVESAQQPKQVLKMEVAVLKKLQGKDHVCRFIGCGRNDRFNYVVMQLQGRNLADLRRSQSRGTFTISTTLRLGRQILESIESIHSVGFLHRDIKP-------------------------------------PRAVAGFRGTVRYASINAHRNREMGRHDDLWSLFYMLVEFVVGQLPWRKIKDKEQVGSIKERYDHRLMLKHLPPEFSIFLDHISSLDYFTKPDYQLLTSVFDNSIKTFGVIESDPFDWEKTGN 267          
BLAST of Protein kinase vs. Ensembl Celegans
Match: ttbk-7 (Tau TuBulin Kinase [Source:UniProtKB/TrEMBL;Acc:Q22033])

HSP 1 Score: 367.081 bits (941), Expect = 1.385e-111
Identity = 167/315 (53.02%), Postives = 221/315 (70.16%), Query Frame = 3
Query:   33 STKQETDLLNPSNIVKDRWKVIRKLGGGGFGEIYECLDSHTQ-EKVALKLESSRIAKQVLKMEVAVLKKLQGTAHVCKFLGCGRNDRFNYVAMTLQGKNLADLRRAQKNSAFSISTMLRLSAQILQSIQDIHNSGFLHRDIKPSNFSMGRLPLSSHTVVMLDFGLARQYILPDGNGDIRAPRPVTGFRGTVRYASVNAHMNREMGRHDDLWSAFYMMAEMVTGSLPWRKLKDKDQVGQIKQNFEHTQLLRHLPSEFKLLLSHIQSLTYFDAPDYEYLKNLIYQCMRRKGISSDELFDWETTSDIRQSVQSSSVTG 974
            ++  E ++L    ++++RWK+  K+GGGGFGEIYE  D     E+VA+K+ESS+  KQVLKMEVAVL++LQG  H CKF GCGRND+FNY+ M+LQGKNLADLRR      F++ST +R+  QIL  I++IH+ GFLHRD+KPSNF+MGR   +   V MLDFGLARQY+  +  G+IR+PR   GFRGTVRYA+V AH N+EMGR DDLWS FYM+ E + G LPWRK+KDKD+VG++K+  +   LL   P E  L ++H++ L Y D PDY YL++L+ + +    IS DE +DWE   D   + Q     G
Sbjct:    2 TSSSEGEILQVGQVIRERWKIKAKIGGGGFGEIYEATDVQNHHERVAIKVESSKATKQVLKMEVAVLRRLQGKKHACKFYGCGRNDKFNYLVMSLQGKNLADLRREAPKQCFNLSTAVRVGIQILNGIREIHSIGFLHRDVKPSNFAMGRTSQTMRNVYMLDFGLARQYL--NAKGEIRSPRSAAGFRGTVRYAAVTAHKNKEMGRQDDLWSLFYMLTEFLQGQLPWRKIKDKDEVGKMKEEADLVVLLDDCPHEMHLFVAHLKVLGYADTPDYVYLESLLNKIVAENEISWDEPYDWELGYDNMATRQKQQANG 314          
BLAST of Protein kinase vs. Ensembl Celegans
Match: C39H7.1 (pep chromosome:WBcel235:IV:5631895:5633379:1 gene:WBGene00016541.1 transcript:C39H7.1.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:C39H7.1)

HSP 1 Score: 228.024 bits (580), Expect = 8.309e-67
Identity = 119/301 (39.53%), Postives = 180/301 (59.80%), Query Frame = 3
Query:   42 QETDLLNPSNIVKDRWKVIRKLGGGGFGEIYECLDSHTQEKVALKLESSRIAKQVLKMEVAVLKKL--QGTAHVCKFLGCGRNDRFNYVAMTLQGKNLADLRRAQKNSAFSISTMLRLSAQILQSIQDIHNSGFLHRDIKPSNFSMGRLPLSS-HTVVMLDFGLARQYILPDGNGDIRAPRPVTGFRGTVRYASVNAHMNREMGRHDDLWSAFYMMAEMVTGSLPWRKLKDKDQVGQIKQNFEH---TQLLRHLPSEFKLLLSHIQSLTYFDAPDYEYLKNLIYQCMRRKGISSDELFDWE 926
            QE   LNP   V +RW + +KLG GGFG +Y   D+    K A+K+E +    QVLK+EV+VL +L  +G  H CK    GR   FNYV MTL GK+L DL +A      S+   + +  Q L++++D+HN G+LHRD+KP N+++GR  L+    V +LDFG+ R++   DG   IR PR   GFRGTV+YA ++ H+ RE+ R DDL +  YM  E+  G++PW+ + D +QVGQ KQ   +   T      P +F+ ++  + ++ Y+DAP+Y+ +  ++ Q     G + +  +DWE
Sbjct:    3 QELIQLNPGQQV-ERWSIEKKLGEGGFGAVYRVFDATG--KYAMKVEGANEQIQVLKLEVSVLNELSKRGNRHFCKIEDKGRFGNFNYVVMTLVGKSLQDLNKAGVGGHMSMGCSIGIGIQSLEALEDLHNIGYLHRDVKPGNYTIGRPELNEIRKVYILDFGMCRKFTGNDGT--IRKPRQAAGFRGTVKYAPISCHLQRELCRKDDLETWMYMQVELSHGTIPWQHISDMNQVGQAKQAIRNNLGTLFPPPCPQQFQDIMRMVDAMKYYDAPNYQAIYGMMRQAYGACGSNENAPYDWE 298          
BLAST of Protein kinase vs. Ensembl Celegans
Match: R13H9.5 (pep chromosome:WBcel235:IV:5065746:5066987:-1 gene:WBGene00020071.1 transcript:R13H9.5.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:R13H9.5)

HSP 1 Score: 228.024 bits (580), Expect = 1.085e-66
Identity = 121/289 (41.87%), Postives = 171/289 (59.17%), Query Frame = 3
Query:   81 DRWKVIRKLGGGGFGEIYECLDSHTQEKVALKLESSRIAKQVLKMEVAVLKKL--QGTAHVCKFLGCGRNDRFNYVAMTLQGKNLADLRRAQKNSAFSISTMLRLSAQILQSIQDIHNSGFLHRDIKPSNFSMGRLPLSS-HTVVMLDFGLARQYILPDGNGDIRAPRPVTGFRGTVRYASVNAHMNREMGRHDDLWSAFYMMAEMVTGSLPWRKLKDKDQVGQIKQNFEHT---QLLRHLPS-EFKLLLSHIQSLTYFDAPDYEYLKNLIYQCMRRKGISSDELFDWE 926
            +RW + +KLG GG G +Y C D+    K ALK+E    A QVLKMEV VL +L  +G+ H CK    GR   FNYV MTL GK+L DLR+       S++  L +  Q L++++D+HN G+LHRD+KP N+++GR  L+    V +LDFG+AR++   D NG IR PR   GFRGTVRYA +  H N+E+GR DD+    YM  E+  G +PW+++ D + VGQ KQ   +T     +   P+ E K ++  + S  YF  P+Y     L+ Q +   G   +  +DWE
Sbjct:   18 ERWSITKKLGEGGCGAVYLCTDATG--KYALKVEGISEAMQVLKMEVLVLGELTKRGSRHFCKIEDKGRYGSFNYVVMTLVGKSLQDLRKGTAQQCLSLACSLSVGIQSLEALEDLHNIGYLHRDVKPGNYTIGRAELNELRKVYILDFGMARKFT--DNNGVIRKPRAAAGFRGTVRYAPIACHKNQELGRKDDVEVWLYMQVELTVGRVPWKEITDMNAVGQAKQTIRNTPEKMFVFPCPANELKEIMKMVDSWDYFADPNYADCYRLMKQALANCG-KPEYPYDWE 301          
BLAST of Protein kinase vs. Ensembl Celegans
Match: ttbk-2 (Tau TuBulin Kinase [Source:UniProtKB/TrEMBL;Acc:O76712])

HSP 1 Score: 227.254 bits (578), Expect = 2.131e-66
Identity = 121/289 (41.87%), Postives = 171/289 (59.17%), Query Frame = 3
Query:   81 DRWKVIRKLGGGGFGEIYECLDSHTQEKVALKLESSRIAKQVLKMEVAVLKKL--QGTAHVCKFLGCGRNDRFNYVAMTLQGKNLADLRRAQKNSAFSISTMLRLSAQILQSIQDIHNSGFLHRDIKPSNFSMGRLPLSS-HTVVMLDFGLARQYILPDGNGDIRAPRPVTGFRGTVRYASVNAHMNREMGRHDDLWSAFYMMAEMVTGSLPWRKLKDKDQVGQIKQNFEHT---QLLRHLPS-EFKLLLSHIQSLTYFDAPDYEYLKNLIYQCMRRKGISSDELFDWE 926
            +RW + +KLG GG G +Y C D+    K ALK+E    A QVLKMEV VL +L  +G+ H CK    GR   FNYV MTL GK+L DLR+       S++  L +  Q L++++D+HN G+LHRD+KP N+++GR  L+    V +LDFG+AR++   D NG IR PR   GFRGTVRYA +  H N+E+GR DD+    YM  E+  G +PW+++ D + VGQ KQ   +T     +   P+ E K ++  + S  YF  P+Y     L+ Q +   G   +  +DWE
Sbjct:   18 ERWSITKKLGEGGCGAVYLCTDATG--KYALKVEGISEAMQVLKMEVLVLGELTKRGSRHFCKIEDKGRYGSFNYVVMTLVGKSLQDLRKGTAQQCLSLACSLSVGIQSLEALEDLHNIGYLHRDVKPGNYTIGRAELNELRKVYILDFGMARKFT--DNNGVIRKPRAAAGFRGTVRYAPIACHKNQELGRKDDVEVWLYMQVELTVGRVPWKEITDMNAVGQAKQAIRNTPEKMFVFPCPANELKEIMKMVDSWDYFADPNYADCYRLMKQTLANCG-KPEYPYDWE 301          
BLAST of Protein kinase vs. Ensembl Celegans
Match: Y38H8A.3 (pep chromosome:WBcel235:IV:13472497:13474005:1 gene:WBGene00012637.1 transcript:Y38H8A.3.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:Y38H8A.3)

HSP 1 Score: 225.713 bits (574), Expect = 6.286e-66
Identity = 117/296 (39.53%), Postives = 178/296 (60.14%), Query Frame = 3
Query:   57 LNPSNIVKDRWKVIRKLGGGGFGEIYECLDSHTQEKVALKLESSRIAKQVLKMEVAVLKKL--QGTAHVCKFLGCGRNDRFNYVAMTLQGKNLADLRRAQKNSAFSISTMLRLSAQILQSIQDIHNSGFLHRDIKPSNFSMGRLPLSS-HTVVMLDFGLARQYILPDGNGDIRAPRPVTGFRGTVRYASVNAHMNREMGRHDDLWSAFYMMAEMVTGSLPWRKLKDKDQVGQIKQNFEH---TQLLRHLPSEFKLLLSHIQSLTYFDAPDYEYLKNLIYQCMRRKGISSDELFDWE 926
            LNP   V +RW + +KLG GGFG +Y   D+    K A+K+E +    QVLK+EV+VL KL  +G  H CK    GR   FNYV MTL GK+L DL +A      S+   + +  Q L++++D+HN G+LHRD+KP N+++GR  L+    V +LDFG+ R++   DG   IR PR   GFRGTV+YA ++ H+ RE+ R DDL +  YM  E+  G++PW+ + D +QVGQ KQ   +   +      P +F+ ++  + ++ Y+DAP+Y+ +  ++ Q     G + +  +DWE
Sbjct:    8 LNPGQQV-ERWSIEKKLGEGGFGAVYRVFDA--TGKYAMKVEGANEQIQVLKLEVSVLNKLSKRGNRHFCKIEDKGRFGNFNYVVMTLVGKSLQDLNKAGVGGHMSMGCSIGIGIQSLEALEDLHNIGYLHRDVKPGNYTIGRPELNEIRKVYILDFGMCRKFTGNDGT--IRKPRQAAGFRGTVKYAPISCHLQRELCRKDDLETWMYMQVELSHGTIPWQYISDMNQVGQAKQAIRNNLGSLFPPPCPHQFQDIMRMVDAMKYYDAPNYQAIYGMMRQAYGACGSNENAPYDWE 298          
BLAST of Protein kinase vs. Ensembl Fly
Match: Asator (gene:FBgn0039908 transcript:FBtr0300344)

HSP 1 Score: 431.024 bits (1107), Expect = 5.780e-135
Identity = 195/292 (66.78%), Postives = 231/292 (79.11%), Query Frame = 3
Query:   51 DLLNPSNIVKDRWKVIRKLGGGGFGEIYECLDSHTQEKVALKLESSRIAKQVLKMEVAVLKKLQGTAHVCKFLGCGRNDRFNYVAMTLQGKNLADLRRAQKNSAFSISTMLRLSAQILQSIQDIHNSGFLHRDIKPSNFSMGRLPLSSHTVVMLDFGLARQYILPDGNGDIRAPRPVTGFRGTVRYASVNAHMNREMGRHDDLWSAFYMMAEMVTGSLPWRKLKDKDQVGQIKQNFEHTQLLRHLPSEFKLLLSHIQSLTYFDAPDYEYLKNLIYQCMRRKGISSDELFDWE 926
            DLL P ++VK+RWKV+RK+GGGGFGEIYE  D  T+E+VALK+ES+R  KQVLKMEVAVLKKLQG  HVC+F+GCGRNDRFNYV M LQGKNLA+LRRAQ   AFS+ST LRL  QIL++I+ IH+ GFLHRDIKPSNFS+GRLP +   V MLDFGLARQY    G G++R PR   GFRGTVRYAS+NAH NREMGRHDDLWS FYM+ E V G LPWRK+KDK+QVG  K+ ++H  LL+HLPS+ K  L HIQSLTY D PDY  L  L  +CM+R+G+   + +DWE
Sbjct:    5 DLLQPGHVVKERWKVVRKIGGGGFGEIYEGQDLITREQVALKVESARQPKQVLKMEVAVLKKLQGKEHVCRFIGCGRNDRFNYVVMQLQGKNLAELRRAQPRGAFSLSTTLRLGLQILKAIESIHSVGFLHRDIKPSNFSVGRLPYNCRRVYMLDFGLARQYTT--GTGEVRCPRAAAGFRGTVRYASINAHRNREMGRHDDLWSLFYMLVEFVNGQLPWRKIKDKEQVGLTKEKYDHRILLKHLPSDLKQFLEHIQSLTYGDRPDYAMLIGLFERCMKRRGVKESDPYDWE 294          
BLAST of Protein kinase vs. Ensembl Fly
Match: Asator (gene:FBgn0039908 transcript:FBtr0344869)

HSP 1 Score: 431.024 bits (1107), Expect = 5.572e-132
Identity = 195/292 (66.78%), Postives = 231/292 (79.11%), Query Frame = 3
Query:   51 DLLNPSNIVKDRWKVIRKLGGGGFGEIYECLDSHTQEKVALKLESSRIAKQVLKMEVAVLKKLQGTAHVCKFLGCGRNDRFNYVAMTLQGKNLADLRRAQKNSAFSISTMLRLSAQILQSIQDIHNSGFLHRDIKPSNFSMGRLPLSSHTVVMLDFGLARQYILPDGNGDIRAPRPVTGFRGTVRYASVNAHMNREMGRHDDLWSAFYMMAEMVTGSLPWRKLKDKDQVGQIKQNFEHTQLLRHLPSEFKLLLSHIQSLTYFDAPDYEYLKNLIYQCMRRKGISSDELFDWE 926
            DLL P ++VK+RWKV+RK+GGGGFGEIYE  D  T+E+VALK+ES+R  KQVLKMEVAVLKKLQG  HVC+F+GCGRNDRFNYV M LQGKNLA+LRRAQ   AFS+ST LRL  QIL++I+ IH+ GFLHRDIKPSNFS+GRLP +   V MLDFGLARQY    G G++R PR   GFRGTVRYAS+NAH NREMGRHDDLWS FYM+ E V G LPWRK+KDK+QVG  K+ ++H  LL+HLPS+ K  L HIQSLTY D PDY  L  L  +CM+R+G+   + +DWE
Sbjct:    5 DLLQPGHVVKERWKVVRKIGGGGFGEIYEGQDLITREQVALKVESARQPKQVLKMEVAVLKKLQGKEHVCRFIGCGRNDRFNYVVMQLQGKNLAELRRAQPRGAFSLSTTLRLGLQILKAIESIHSVGFLHRDIKPSNFSVGRLPYNCRRVYMLDFGLARQYTT--GTGEVRCPRAAAGFRGTVRYASINAHRNREMGRHDDLWSLFYMLVEFVNGQLPWRKIKDKEQVGLTKEKYDHRILLKHLPSDLKQFLEHIQSLTYGDRPDYAMLIGLFERCMKRRGVKESDPYDWE 294          
BLAST of Protein kinase vs. Ensembl Fly
Match: Asator (gene:FBgn0039908 transcript:FBtr0332908)

HSP 1 Score: 431.024 bits (1107), Expect = 5.572e-132
Identity = 195/292 (66.78%), Postives = 231/292 (79.11%), Query Frame = 3
Query:   51 DLLNPSNIVKDRWKVIRKLGGGGFGEIYECLDSHTQEKVALKLESSRIAKQVLKMEVAVLKKLQGTAHVCKFLGCGRNDRFNYVAMTLQGKNLADLRRAQKNSAFSISTMLRLSAQILQSIQDIHNSGFLHRDIKPSNFSMGRLPLSSHTVVMLDFGLARQYILPDGNGDIRAPRPVTGFRGTVRYASVNAHMNREMGRHDDLWSAFYMMAEMVTGSLPWRKLKDKDQVGQIKQNFEHTQLLRHLPSEFKLLLSHIQSLTYFDAPDYEYLKNLIYQCMRRKGISSDELFDWE 926
            DLL P ++VK+RWKV+RK+GGGGFGEIYE  D  T+E+VALK+ES+R  KQVLKMEVAVLKKLQG  HVC+F+GCGRNDRFNYV M LQGKNLA+LRRAQ   AFS+ST LRL  QIL++I+ IH+ GFLHRDIKPSNFS+GRLP +   V MLDFGLARQY    G G++R PR   GFRGTVRYAS+NAH NREMGRHDDLWS FYM+ E V G LPWRK+KDK+QVG  K+ ++H  LL+HLPS+ K  L HIQSLTY D PDY  L  L  +CM+R+G+   + +DWE
Sbjct:    5 DLLQPGHVVKERWKVVRKIGGGGFGEIYEGQDLITREQVALKVESARQPKQVLKMEVAVLKKLQGKEHVCRFIGCGRNDRFNYVVMQLQGKNLAELRRAQPRGAFSLSTTLRLGLQILKAIESIHSVGFLHRDIKPSNFSVGRLPYNCRRVYMLDFGLARQYTT--GTGEVRCPRAAAGFRGTVRYASINAHRNREMGRHDDLWSLFYMLVEFVNGQLPWRKIKDKEQVGLTKEKYDHRILLKHLPSDLKQFLEHIQSLTYGDRPDYAMLIGLFERCMKRRGVKESDPYDWE 294          
BLAST of Protein kinase vs. Ensembl Fly
Match: Asator (gene:FBgn0039908 transcript:FBtr0332905)

HSP 1 Score: 432.18 bits (1110), Expect = 1.413e-131
Identity = 195/292 (66.78%), Postives = 231/292 (79.11%), Query Frame = 3
Query:   51 DLLNPSNIVKDRWKVIRKLGGGGFGEIYECLDSHTQEKVALKLESSRIAKQVLKMEVAVLKKLQGTAHVCKFLGCGRNDRFNYVAMTLQGKNLADLRRAQKNSAFSISTMLRLSAQILQSIQDIHNSGFLHRDIKPSNFSMGRLPLSSHTVVMLDFGLARQYILPDGNGDIRAPRPVTGFRGTVRYASVNAHMNREMGRHDDLWSAFYMMAEMVTGSLPWRKLKDKDQVGQIKQNFEHTQLLRHLPSEFKLLLSHIQSLTYFDAPDYEYLKNLIYQCMRRKGISSDELFDWE 926
            DLL P ++VK+RWKV+RK+GGGGFGEIYE  D  T+E+VALK+ES+R  KQVLKMEVAVLKKLQG  HVC+F+GCGRNDRFNYV M LQGKNLA+LRRAQ   AFS+ST LRL  QIL++I+ IH+ GFLHRDIKPSNFS+GRLP +   V MLDFGLARQY    G G++R PR   GFRGTVRYAS+NAH NREMGRHDDLWS FYM+ E V G LPWRK+KDK+QVG  K+ ++H  LL+HLPS+ K  L HIQSLTY D PDY  L  L  +CM+R+G+   + +DWE
Sbjct:    5 DLLQPGHVVKERWKVVRKIGGGGFGEIYEGQDLITREQVALKVESARQPKQVLKMEVAVLKKLQGKEHVCRFIGCGRNDRFNYVVMQLQGKNLAELRRAQPRGAFSLSTTLRLGLQILKAIESIHSVGFLHRDIKPSNFSVGRLPYNCRRVYMLDFGLARQYTT--GTGEVRCPRAAAGFRGTVRYASINAHRNREMGRHDDLWSLFYMLVEFVNGQLPWRKIKDKEQVGLTKEKYDHRILLKHLPSDLKQFLEHIQSLTYGDRPDYAMLIGLFERCMKRRGVKESDPYDWE 294          
BLAST of Protein kinase vs. Ensembl Fly
Match: Asator (gene:FBgn0039908 transcript:FBtr0332904)

HSP 1 Score: 430.639 bits (1106), Expect = 1.751e-131
Identity = 195/292 (66.78%), Postives = 231/292 (79.11%), Query Frame = 3
Query:   51 DLLNPSNIVKDRWKVIRKLGGGGFGEIYECLDSHTQEKVALKLESSRIAKQVLKMEVAVLKKLQGTAHVCKFLGCGRNDRFNYVAMTLQGKNLADLRRAQKNSAFSISTMLRLSAQILQSIQDIHNSGFLHRDIKPSNFSMGRLPLSSHTVVMLDFGLARQYILPDGNGDIRAPRPVTGFRGTVRYASVNAHMNREMGRHDDLWSAFYMMAEMVTGSLPWRKLKDKDQVGQIKQNFEHTQLLRHLPSEFKLLLSHIQSLTYFDAPDYEYLKNLIYQCMRRKGISSDELFDWE 926
            DLL P ++VK+RWKV+RK+GGGGFGEIYE  D  T+E+VALK+ES+R  KQVLKMEVAVLKKLQG  HVC+F+GCGRNDRFNYV M LQGKNLA+LRRAQ   AFS+ST LRL  QIL++I+ IH+ GFLHRDIKPSNFS+GRLP +   V MLDFGLARQY    G G++R PR   GFRGTVRYAS+NAH NREMGRHDDLWS FYM+ E V G LPWRK+KDK+QVG  K+ ++H  LL+HLPS+ K  L HIQSLTY D PDY  L  L  +CM+R+G+   + +DWE
Sbjct:  161 DLLQPGHVVKERWKVVRKIGGGGFGEIYEGQDLITREQVALKVESARQPKQVLKMEVAVLKKLQGKEHVCRFIGCGRNDRFNYVVMQLQGKNLAELRRAQPRGAFSLSTTLRLGLQILKAIESIHSVGFLHRDIKPSNFSVGRLPYNCRRVYMLDFGLARQYTT--GTGEVRCPRAAAGFRGTVRYASINAHRNREMGRHDDLWSLFYMLVEFVNGQLPWRKIKDKEQVGLTKEKYDHRILLKHLPSDLKQFLEHIQSLTYGDRPDYAMLIGLFERCMKRRGVKESDPYDWE 450          
BLAST of Protein kinase vs. Ensembl Zebrafish
Match: ttbk1a (tau tubulin kinase 1a [Source:ZFIN;Acc:ZDB-GENE-100609-4])

HSP 1 Score: 423.32 bits (1087), Expect = 1.474e-127
Identity = 188/300 (62.67%), Postives = 234/300 (78.00%), Query Frame = 3
Query:   27 MPSTKQETDLLNPSNIVKDRWKVIRKLGGGGFGEIYECLDSHTQEKVALKLESSRIAKQVLKMEVAVLKKLQGTAHVCKFLGCGRNDRFNYVAMTLQGKNLADLRRAQKNSAFSISTMLRLSAQILQSIQDIHNSGFLHRDIKPSNFSMGRLPLSSHTVVMLDFGLARQYILPDGNGDIRAPRPVTGFRGTVRYASVNAHMNREMGRHDDLWSAFYMMAEMVTGSLPWRKLKDKDQVGQIKQNFEHTQLLRHLPSEFKLLLSHIQSLTYFDAPDYEYLKNLIYQCMRRKGISSDELFDWE 926
            M  T ++ D+L P  +VKDRWKV++K+GGGGFGEIYE LD  T+E VALK+ES++  KQVLKMEVAVLKKLQG  HVCKF+GCGRND+FNYV M LQG+NLADLRR+Q    F++ST LRL  QIL+SI+ IH+ GFLHRDIKPSNF+MGRLP +     MLDFGLARQY   + NG++R PR V GFRGTVRYASVNAH N+EMGRHDDLWS FYM+ E   G LPWRK+KDK+QVGQIK+ ++H  LL+H+PSEF + L H+ +L Y+  PDY+ L ++    M+ + I+ +E +DWE
Sbjct:    1 MNGTAEQQDILPPHCMVKDRWKVLKKIGGGGFGEIYEALDLLTRENVALKVESAQQPKQVLKMEVAVLKKLQGKNHVCKFIGCGRNDKFNYVVMQLQGRNLADLRRSQPRGTFTMSTTLRLGKQILESIEAIHSVGFLHRDIKPSNFAMGRLPSTFRKCYMLDFGLARQYT--NTNGEVRPPRTVAGFRGTVRYASVNAHKNKEMGRHDDLWSLFYMLVEFAAGQLPWRKIKDKEQVGQIKERYDHRMLLKHMPSEFNVFLEHVLALDYYTKPDYQLLMSVFENSMKERIITENEPYDWE 298          
BLAST of Protein kinase vs. Ensembl Zebrafish
Match: ttbk1a (tau tubulin kinase 1a [Source:ZFIN;Acc:ZDB-GENE-100609-4])

HSP 1 Score: 423.32 bits (1087), Expect = 1.474e-127
Identity = 188/300 (62.67%), Postives = 234/300 (78.00%), Query Frame = 3
Query:   27 MPSTKQETDLLNPSNIVKDRWKVIRKLGGGGFGEIYECLDSHTQEKVALKLESSRIAKQVLKMEVAVLKKLQGTAHVCKFLGCGRNDRFNYVAMTLQGKNLADLRRAQKNSAFSISTMLRLSAQILQSIQDIHNSGFLHRDIKPSNFSMGRLPLSSHTVVMLDFGLARQYILPDGNGDIRAPRPVTGFRGTVRYASVNAHMNREMGRHDDLWSAFYMMAEMVTGSLPWRKLKDKDQVGQIKQNFEHTQLLRHLPSEFKLLLSHIQSLTYFDAPDYEYLKNLIYQCMRRKGISSDELFDWE 926
            M  T ++ D+L P  +VKDRWKV++K+GGGGFGEIYE LD  T+E VALK+ES++  KQVLKMEVAVLKKLQG  HVCKF+GCGRND+FNYV M LQG+NLADLRR+Q    F++ST LRL  QIL+SI+ IH+ GFLHRDIKPSNF+MGRLP +     MLDFGLARQY   + NG++R PR V GFRGTVRYASVNAH N+EMGRHDDLWS FYM+ E   G LPWRK+KDK+QVGQIK+ ++H  LL+H+PSEF + L H+ +L Y+  PDY+ L ++    M+ + I+ +E +DWE
Sbjct:    1 MNGTAEQQDILPPHCMVKDRWKVLKKIGGGGFGEIYEALDLLTRENVALKVESAQQPKQVLKMEVAVLKKLQGKNHVCKFIGCGRNDKFNYVVMQLQGRNLADLRRSQPRGTFTMSTTLRLGKQILESIEAIHSVGFLHRDIKPSNFAMGRLPSTFRKCYMLDFGLARQYT--NTNGEVRPPRTVAGFRGTVRYASVNAHKNKEMGRHDDLWSLFYMLVEFAAGQLPWRKIKDKEQVGQIKERYDHRMLLKHMPSEFNVFLEHVLALDYYTKPDYQLLMSVFENSMKERIITENEPYDWE 298          
BLAST of Protein kinase vs. Ensembl Zebrafish
Match: ttbk1b (tau tubulin kinase 1b [Source:ZFIN;Acc:ZDB-GENE-100609-5])

HSP 1 Score: 415.616 bits (1067), Expect = 4.091e-125
Identity = 184/295 (62.37%), Postives = 229/295 (77.63%), Query Frame = 3
Query:   42 QETDLLNPSNIVKDRWKVIRKLGGGGFGEIYECLDSHTQEKVALKLESSRIAKQVLKMEVAVLKKLQGTAHVCKFLGCGRNDRFNYVAMTLQGKNLADLRRAQKNSAFSISTMLRLSAQILQSIQDIHNSGFLHRDIKPSNFSMGRLPLSSHTVVMLDFGLARQYILPDGNGDIRAPRPVTGFRGTVRYASVNAHMNREMGRHDDLWSAFYMMAEMVTGSLPWRKLKDKDQVGQIKQNFEHTQLLRHLPSEFKLLLSHIQSLTYFDAPDYEYLKNLIYQCMRRKGISSDELFDWE 926
            ++ D+L  + +VKDRWKV++K+GGGGFGEIYE  D  T+E VALK+ES++  KQVLKMEVAVLKKLQG  HVCKF+GCGRND+FNYV M LQG+NLADLRR+Q    FS+ST LRL  QIL+SI+ IH+ GFLHRDIKPSNF+MGRLP +     MLDFGLARQY   + NG++R PR V GFRGTVRYAS+NAH N+EMGRHDDLWS FYM+ E   G LPWRK+KDK+QVGQIK+ +EH  LL+H+P+EF +   H+  L YF  PDY+ L ++    M+ + I+ +E +DWE
Sbjct:   19 EQVDILPSNCLVKDRWKVLKKIGGGGFGEIYEAYDLLTRENVALKVESAQQPKQVLKMEVAVLKKLQGKNHVCKFIGCGRNDKFNYVVMQLQGRNLADLRRSQPRGTFSMSTTLRLGKQILESIEAIHSVGFLHRDIKPSNFAMGRLPSTCRKCYMLDFGLARQYT--NTNGEVRPPRSVAGFRGTVRYASINAHKNKEMGRHDDLWSLFYMLVEFTVGQLPWRKIKDKEQVGQIKERYEHRMLLKHMPAEFHIFYDHVLDLDYFTKPDYQLLMSVFENSMKDRVITENEPYDWE 311          
BLAST of Protein kinase vs. Ensembl Zebrafish
Match: ttbk2a (tau tubulin kinase 2a [Source:ZFIN;Acc:ZDB-GENE-120928-3])

HSP 1 Score: 404.445 bits (1038), Expect = 3.189e-122
Identity = 181/325 (55.69%), Postives = 240/325 (73.85%), Query Frame = 3
Query:   42 QETDLLNPSNIVKDRWKVIRKLGGGGFGEIYECLDSHTQEKVALKLESSRIAKQVLKMEVAVLKKLQGTAHVCKFLGCGRNDRFNYVAMTLQGKNLADLRRAQKNSAFSISTMLRLSAQILQSIQDIHNSGFLHRDIKPSNFSMGRLPLSSHTVVMLDFGLARQYILPDGNGDIRAPRPVTGFRGTVRYASVNAHMNREMGRHDDLWSAFYMMAEMVTGSLPWRKLKDKDQVGQIKQNFEHTQLLRHLPSEFKLLLSHIQSLTYFDAPDYEYLKNLIYQCMRRKGISSDELFDWE-TTSDIRQSVQSSSVTGGRNPHHNFRKKPT 1013
            ++ D+L+   +VK+RWK+++K+GGGGFGEIYE LD  T+  VALK ES++  KQVLKMEVAVLKKLQG  HVC+F+GCGRNDRFNYV M LQG+NLADLRR+     F++ST LRL  QIL++I+ IH+ GFLHRDIKPSNF+MGR P +  T  MLDFGLARQ+   +   ++R PRPV GFRGTVRYAS+NAH N+EMGRHDDLWS FYM+ E + G LPWRK+KDK+QVG++K+ ++H  +L+HLP +F + L HI +L YF  PDY+ L+ +    MR   +  ++ +DWE  +SD   ++ +++ T    P H+ R  P 
Sbjct:    6 EQIDILSTGILVKERWKILKKIGGGGFGEIYEALDLMTRTSVALKAESAQQPKQVLKMEVAVLKKLQGKDHVCRFVGCGRNDRFNYVVMELQGRNLADLRRSMNRGTFTVSTTLRLGLQILEAIESIHSVGFLHRDIKPSNFAMGRFPSTCRTCYMLDFGLARQFT--NSCQEVRPPRPVAGFRGTVRYASINAHKNKEMGRHDDLWSLFYMLVEFLVGQLPWRKIKDKEQVGKLKETYDHRLMLKHLPPQFTVFLDHISNLDYFTKPDYQLLRTVFENSMRTYNVVENDPYDWERISSDSPMTITATANT----PQHHTRLTPA 324          
BLAST of Protein kinase vs. Ensembl Zebrafish
Match: ttbk2a (tau tubulin kinase 2a [Source:ZFIN;Acc:ZDB-GENE-120928-3])

HSP 1 Score: 405.216 bits (1040), Expect = 1.575e-121
Identity = 181/325 (55.69%), Postives = 240/325 (73.85%), Query Frame = 3
Query:   42 QETDLLNPSNIVKDRWKVIRKLGGGGFGEIYECLDSHTQEKVALKLESSRIAKQVLKMEVAVLKKLQGTAHVCKFLGCGRNDRFNYVAMTLQGKNLADLRRAQKNSAFSISTMLRLSAQILQSIQDIHNSGFLHRDIKPSNFSMGRLPLSSHTVVMLDFGLARQYILPDGNGDIRAPRPVTGFRGTVRYASVNAHMNREMGRHDDLWSAFYMMAEMVTGSLPWRKLKDKDQVGQIKQNFEHTQLLRHLPSEFKLLLSHIQSLTYFDAPDYEYLKNLIYQCMRRKGISSDELFDWE-TTSDIRQSVQSSSVTGGRNPHHNFRKKPT 1013
            ++ D+L+   +VK+RWK+++K+GGGGFGEIYE LD  T+  VALK ES++  KQVLKMEVAVLKKLQG  HVC+F+GCGRNDRFNYV M LQG+NLADLRR+     F++ST LRL  QIL++I+ IH+ GFLHRDIKPSNF+MGR P +  T  MLDFGLARQ+   +   ++R PRPV GFRGTVRYAS+NAH N+EMGRHDDLWS FYM+ E + G LPWRK+KDK+QVG++K+ ++H  +L+HLP +F + L HI +L YF  PDY+ L+ +    MR   +  ++ +DWE  +SD   ++ +++ T    P H+ R  P 
Sbjct:    6 EQIDILSTGILVKERWKILKKIGGGGFGEIYEALDLMTRTSVALKAESAQQPKQVLKMEVAVLKKLQGKDHVCRFVGCGRNDRFNYVVMELQGRNLADLRRSMNRGTFTVSTTLRLGLQILEAIESIHSVGFLHRDIKPSNFAMGRFPSTCRTCYMLDFGLARQFT--NSCQEVRPPRPVAGFRGTVRYASINAHKNKEMGRHDDLWSLFYMLVEFLVGQLPWRKIKDKEQVGKLKETYDHRLMLKHLPPQFTVFLDHISNLDYFTKPDYQLLRTVFENSMRTYNVVENDPYDWERISSDSPMTITATANT----PQHHTRLTPA 324          
BLAST of Protein kinase vs. Ensembl Xenopus
Match: col24a1 (collagen, type XXIV, alpha 1 [Source:Xenbase;Acc:XB-GENE-980334])

HSP 1 Score: 412.92 bits (1060), Expect = 8.207e-128
Identity = 189/301 (62.79%), Postives = 228/301 (75.75%), Query Frame = 3
Query:   24 TMPSTKQETDLLNPSNIVKDRWKVIRKLGGGGFGEIYECLDSHTQEKVALKLESSRIAKQVLKMEVAVLKKLQGTAHVCKFLGCGRNDRFNYVAMTLQGKNLADLRRAQKNSAFSISTMLRLSAQILQSIQDIHNSGFLHRDIKPSNFSMGRLPLSSHTVVMLDFGLARQYILPDGNGDIRAPRPVTGFRGTVRYASVNAHMNREMGRHDDLWSAFYMMAEMVTGSLPWRKLKDKDQVGQIKQNFEHTQLLRHLPSEFKLLLSHIQSLTYFDAPDYEYLKNLIYQCMRRKGISSDELFDWE 926
             M    ++ D+L+   +VK+RWKV+RK+GGGGFGEIY+ LD  T+E VALK+ES++  KQVLKMEVAVLKKLQG  HVC+F+GCGRNDRFNYV M LQG+NLADLRR+Q    FSISTMLRL  QIL+SI+ IH+ GFLHRDIKPSNF+MGR P +     MLDFGLARQ+   +  GD+R PR V GFRGTVRYASVNAH NREMGRHDDLWS FYM+ E V G LPWRK+KDK+QVG IK+ +EH  +L+HLP EF + L HI  L YF  PDY+ L ++    M+  G+   + FDWE
Sbjct:   11 AMSGGGEQPDILSVGILVKERWKVLRKIGGGGFGEIYDALDLLTRENVALKVESAQQPKQVLKMEVAVLKKLQGKDHVCRFIGCGRNDRFNYVVMQLQGRNLADLRRSQSRGTFSISTMLRLGRQILESIESIHSVGFLHRDIKPSNFAMGRFPSTCRKCYMLDFGLARQFT--NSCGDVRPPRAVAGFRGTVRYASVNAHRNREMGRHDDLWSLFYMLVEFVVGQLPWRKIKDKEQVGSIKERYEHRLMLKHLPPEFSVFLEHIIGLDYFTKPDYQLLVSVFDNSMKTFGVLESDPFDWE 309          
BLAST of Protein kinase vs. Ensembl Xenopus
Match: col24a1 (collagen, type XXIV, alpha 1 [Source:Xenbase;Acc:XB-GENE-980334])

HSP 1 Score: 414.461 bits (1064), Expect = 1.184e-124
Identity = 189/300 (63.00%), Postives = 228/300 (76.00%), Query Frame = 3
Query:   27 MPSTKQETDLLNPSNIVKDRWKVIRKLGGGGFGEIYECLDSHTQEKVALKLESSRIAKQVLKMEVAVLKKLQGTAHVCKFLGCGRNDRFNYVAMTLQGKNLADLRRAQKNSAFSISTMLRLSAQILQSIQDIHNSGFLHRDIKPSNFSMGRLPLSSHTVVMLDFGLARQYILPDGNGDIRAPRPVTGFRGTVRYASVNAHMNREMGRHDDLWSAFYMMAEMVTGSLPWRKLKDKDQVGQIKQNFEHTQLLRHLPSEFKLLLSHIQSLTYFDAPDYEYLKNLIYQCMRRKGISSDELFDWE 926
            M    ++ D+L+   +VK+RWKV+RK+GGGGFGEIY+ LD  T+E VALK+ES++  KQVLKMEVAVLKKLQG  HVC+F+GCGRNDRFNYV M LQG+NLADLRR+Q    FSISTMLRL  QIL+SI+ IH+ GFLHRDIKPSNF+MGR P +     MLDFGLARQ+   +  GD+R PR V GFRGTVRYASVNAH NREMGRHDDLWS FYM+ E V G LPWRK+KDK+QVG IK+ +EH  +L+HLP EF + L HI  L YF  PDY+ L ++    M+  G+   + FDWE
Sbjct:    1 MSGGGEQPDILSVGILVKERWKVLRKIGGGGFGEIYDALDLLTRENVALKVESAQQPKQVLKMEVAVLKKLQGKDHVCRFIGCGRNDRFNYVVMQLQGRNLADLRRSQSRGTFSISTMLRLGRQILESIESIHSVGFLHRDIKPSNFAMGRFPSTCRKCYMLDFGLARQFT--NSCGDVRPPRAVAGFRGTVRYASVNAHRNREMGRHDDLWSLFYMLVEFVVGQLPWRKIKDKEQVGSIKERYEHRLMLKHLPPEFSVFLEHIIGLDYFTKPDYQLLVSVFDNSMKTFGVLESDPFDWE 298          
BLAST of Protein kinase vs. Ensembl Xenopus
Match: col24a1 (collagen, type XXIV, alpha 1 [Source:Xenbase;Acc:XB-GENE-980334])

HSP 1 Score: 415.616 bits (1067), Expect = 2.076e-124
Identity = 188/295 (63.73%), Postives = 227/295 (76.95%), Query Frame = 3
Query:   42 QETDLLNPSNIVKDRWKVIRKLGGGGFGEIYECLDSHTQEKVALKLESSRIAKQVLKMEVAVLKKLQGTAHVCKFLGCGRNDRFNYVAMTLQGKNLADLRRAQKNSAFSISTMLRLSAQILQSIQDIHNSGFLHRDIKPSNFSMGRLPLSSHTVVMLDFGLARQYILPDGNGDIRAPRPVTGFRGTVRYASVNAHMNREMGRHDDLWSAFYMMAEMVTGSLPWRKLKDKDQVGQIKQNFEHTQLLRHLPSEFKLLLSHIQSLTYFDAPDYEYLKNLIYQCMRRKGISSDELFDWE 926
            ++ D+L+   +VK+RWKV+RK+GGGGFGEIY+ LD  T+E VALK+ES++  KQVLKMEVAVLKKLQG  HVC+F+GCGRNDRFNYV M LQG+NLADLRR+Q    FSISTMLRL  QIL+SI+ IH+ GFLHRDIKPSNF+MGR P +     MLDFGLARQ+   +  GD+R PR V GFRGTVRYASVNAH NREMGRHDDLWS FYM+ E V G LPWRK+KDK+QVG IK+ +EH  +L+HLP EF + L HI  L YF  PDY+ L ++    M+  G+   + FDWE
Sbjct:    6 EQPDILSVGILVKERWKVLRKIGGGGFGEIYDALDLLTRENVALKVESAQQPKQVLKMEVAVLKKLQGKDHVCRFIGCGRNDRFNYVVMQLQGRNLADLRRSQSRGTFSISTMLRLGRQILESIESIHSVGFLHRDIKPSNFAMGRFPSTCRKCYMLDFGLARQFT--NSCGDVRPPRAVAGFRGTVRYASVNAHRNREMGRHDDLWSLFYMLVEFVVGQLPWRKIKDKEQVGSIKERYEHRLMLKHLPPEFSVFLEHIIGLDYFTKPDYQLLVSVFDNSMKTFGVLESDPFDWE 298          
BLAST of Protein kinase vs. Ensembl Xenopus
Match: col24a1 (collagen, type XXIV, alpha 1 [Source:Xenbase;Acc:XB-GENE-980334])

HSP 1 Score: 394.815 bits (1013), Expect = 3.531e-121
Identity = 181/279 (64.87%), Postives = 214/279 (76.70%), Query Frame = 3
Query:   90 KVIRKLGGGGFGEIYECLDSHTQEKVALKLESSRIAKQVLKMEVAVLKKLQGTAHVCKFLGCGRNDRFNYVAMTLQGKNLADLRRAQKNSAFSISTMLRLSAQILQSIQDIHNSGFLHRDIKPSNFSMGRLPLSSHTVVMLDFGLARQYILPDGNGDIRAPRPVTGFRGTVRYASVNAHMNREMGRHDDLWSAFYMMAEMVTGSLPWRKLKDKDQVGQIKQNFEHTQLLRHLPSEFKLLLSHIQSLTYFDAPDYEYLKNLIYQCMRRKGISSDELFDWE 926
            K +RK+GGGGFGEIY+ LD  T+E VALK+ES++  KQVLKMEVAVLKKLQG  HVC+F+GCGRNDRFNYV M LQG+NLADLRR+Q    FSISTMLRL  QIL+SI+ IH+ GFLHRDIKPSNF+MGR P +     MLDFGLARQ+   +  GD+R PR V GFRGTVRYASVNAH NREMGRHDDLWS FYM+ E V G LPWRK+KDK+QVG IK+ +EH  +L+HLP EF + L HI  L YF  PDY+ L ++    M+  G+   + FDWE
Sbjct:   19 KELRKIGGGGFGEIYDALDLLTRENVALKVESAQQPKQVLKMEVAVLKKLQGKDHVCRFIGCGRNDRFNYVVMQLQGRNLADLRRSQSRGTFSISTMLRLGRQILESIESIHSVGFLHRDIKPSNFAMGRFPSTCRKCYMLDFGLARQFT--NSCGDVRPPRAVAGFRGTVRYASVNAHRNREMGRHDDLWSLFYMLVEFVVGQLPWRKIKDKEQVGSIKERYEHRLMLKHLPPEFSVFLEHIIGLDYFTKPDYQLLVSVFDNSMKTFGVLESDPFDWE 295          
BLAST of Protein kinase vs. Ensembl Xenopus
Match: col24a1 (collagen, type XXIV, alpha 1 [Source:Xenbase;Acc:XB-GENE-980334])

HSP 1 Score: 353.984 bits (907), Expect = 2.323e-110
Identity = 170/303 (56.11%), Postives = 205/303 (67.66%), Query Frame = 3
Query:   27 MPSTKQETDLLNPSNIVKDRWKVIRKLGGGGFGEIYECLDSHTQEKVALKLESSRIAKQVLKMEVAVLKKLQGTAHVCKFLGCGRNDRFNYVAMTLQGKNLADLRRAQKNSAFSISTMLRLSAQILQSIQDIHNSGFLHRDIKPSNFSMGRLPLSSHTVVMLDFGLARQYILPDGNGDIRAPRPVTGFRGTVRYASVNAHMNREMGRHDDLWSAFYMMAEMVTGSLPWRKLKDKDQVGQIKQNFEHTQLLRHLPSEFKLLLSHIQSLTYFDAPDYEYLKNLIYQCMRRKGISSDELFDWETTS 935
            M    ++ D+L+   +VK+RWKV+RK+GGGGFGEIY+ LD  T+E VALK+ES++  KQVLKMEVAVLKKLQG  HVC+F+GCGRNDRFNYV M LQG+NLADLRR+Q    FSISTMLRL  QIL+SI+ IH+ GFLHRDIKP                                     PR V GFRGTVRYASVNAH NREMGRHDDLWS FYM+ E V G LPWRK+KDK+QVG IK+ +EH  +L+HLP EF + L HI  L YF  PDY+ L ++    M+  G+   + FDWE + 
Sbjct:    1 MSGGGEQPDILSVGILVKERWKVLRKIGGGGFGEIYDALDLLTRENVALKVESAQQPKQVLKMEVAVLKKLQGKDHVCRFIGCGRNDRFNYVVMQLQGRNLADLRRSQSRGTFSISTMLRLGRQILESIESIHSVGFLHRDIKP-------------------------------------PRAVAGFRGTVRYASVNAHRNREMGRHDDLWSLFYMLVEFVVGQLPWRKIKDKEQVGSIKERYEHRLMLKHLPPEFSVFLEHIIGLDYFTKPDYQLLVSVFDNSMKTFGVLESDPFDWEKSG 266          
BLAST of Protein kinase vs. Ensembl Mouse
Match: Ttbk1 (tau tubulin kinase 1 [Source:MGI Symbol;Acc:MGI:2147036])

HSP 1 Score: 420.624 bits (1080), Expect = 1.886e-131
Identity = 188/295 (63.73%), Postives = 231/295 (78.31%), Query Frame = 3
Query:   42 QETDLLNPSNIVKDRWKVIRKLGGGGFGEIYECLDSHTQEKVALKLESSRIAKQVLKMEVAVLKKLQGTAHVCKFLGCGRNDRFNYVAMTLQGKNLADLRRAQKNSAFSISTMLRLSAQILQSIQDIHNSGFLHRDIKPSNFSMGRLPLSSHTVVMLDFGLARQYILPDGNGDIRAPRPVTGFRGTVRYASVNAHMNREMGRHDDLWSAFYMMAEMVTGSLPWRKLKDKDQVGQIKQNFEHTQLLRHLPSEFKLLLSHIQSLTYFDAPDYEYLKNLIYQCMRRKGISSDELFDWE 926
            ++ D+L  + +VKDRWKV++K+GGGGFGEIYE +D  T+E VALK+ES++  KQVLKMEVAVLKKLQG  HVC+F+GCGRN++FNYV M LQG+NLADLRR+Q    F++ST LRL  QIL+SI+ IH+ GFLHRDIKPSNF+MGRLP +     MLDFGLARQY   +  GD+R PR V GFRGTVRYASVNAH NREMGRHDDLWS FYM+ E   G LPWRK+KDK+QVG IK+ +EH  LL+H+PSEF L L HI SL YF  PDY+ + ++    M+ +GI+ +E FDWE
Sbjct:   19 EQADILPANYVVKDRWKVLKKIGGGGFGEIYEAMDLLTRENVALKVESAQQPKQVLKMEVAVLKKLQGKDHVCRFIGCGRNEKFNYVVMQLQGRNLADLRRSQPRGTFTLSTTLRLGKQILESIEAIHSVGFLHRDIKPSNFAMGRLPSTYRKCYMLDFGLARQYT--NTTGDVRPPRNVAGFRGTVRYASVNAHKNREMGRHDDLWSLFYMLVEFAVGQLPWRKIKDKEQVGMIKEKYEHRMLLKHMPSEFHLFLDHIASLDYFTKPDYQLIMSVFENSMKERGIAENEAFDWE 311          
BLAST of Protein kinase vs. Ensembl Mouse
Match: Ttbk1 (tau tubulin kinase 1 [Source:MGI Symbol;Acc:MGI:2147036])

HSP 1 Score: 426.017 bits (1094), Expect = 3.202e-128
Identity = 188/295 (63.73%), Postives = 231/295 (78.31%), Query Frame = 3
Query:   42 QETDLLNPSNIVKDRWKVIRKLGGGGFGEIYECLDSHTQEKVALKLESSRIAKQVLKMEVAVLKKLQGTAHVCKFLGCGRNDRFNYVAMTLQGKNLADLRRAQKNSAFSISTMLRLSAQILQSIQDIHNSGFLHRDIKPSNFSMGRLPLSSHTVVMLDFGLARQYILPDGNGDIRAPRPVTGFRGTVRYASVNAHMNREMGRHDDLWSAFYMMAEMVTGSLPWRKLKDKDQVGQIKQNFEHTQLLRHLPSEFKLLLSHIQSLTYFDAPDYEYLKNLIYQCMRRKGISSDELFDWE 926
            ++ D+L  + +VKDRWKV++K+GGGGFGEIYE +D  T+E VALK+ES++  KQVLKMEVAVLKKLQG  HVC+F+GCGRN++FNYV M LQG+NLADLRR+Q    F++ST LRL  QIL+SI+ IH+ GFLHRDIKPSNF+MGRLP +     MLDFGLARQY   +  GD+R PR V GFRGTVRYASVNAH NREMGRHDDLWS FYM+ E   G LPWRK+KDK+QVG IK+ +EH  LL+H+PSEF L L HI SL YF  PDY+ + ++    M+ +GI+ +E FDWE
Sbjct:   19 EQADILPANYVVKDRWKVLKKIGGGGFGEIYEAMDLLTRENVALKVESAQQPKQVLKMEVAVLKKLQGKDHVCRFIGCGRNEKFNYVVMQLQGRNLADLRRSQPRGTFTLSTTLRLGKQILESIEAIHSVGFLHRDIKPSNFAMGRLPSTYRKCYMLDFGLARQYT--NTTGDVRPPRNVAGFRGTVRYASVNAHKNREMGRHDDLWSLFYMLVEFAVGQLPWRKIKDKEQVGMIKEKYEHRMLLKHMPSEFHLFLDHIASLDYFTKPDYQLIMSVFENSMKERGIAENEAFDWE 311          
BLAST of Protein kinase vs. Ensembl Mouse
Match: Ttbk2 (tau tubulin kinase 2 [Source:MGI Symbol;Acc:MGI:2155779])

HSP 1 Score: 408.297 bits (1048), Expect = 1.101e-125
Identity = 185/300 (61.67%), Postives = 227/300 (75.67%), Query Frame = 3
Query:   27 MPSTKQETDLLNPSNIVKDRWKVIRKLGGGGFGEIYECLDSHTQEKVALKLESSRIAKQVLKMEVAVLKKLQGTAHVCKFLGCGRNDRFNYVAMTLQGKNLADLRRAQKNSAFSISTMLRLSAQILQSIQDIHNSGFLHRDIKPSNFSMGRLPLSSHTVVMLDFGLARQYILPDGNGDIRAPRPVTGFRGTVRYASVNAHMNREMGRHDDLWSAFYMMAEMVTGSLPWRKLKDKDQVGQIKQNFEHTQLLRHLPSEFKLLLSHIQSLTYFDAPDYEYLKNLIYQCMRRKGISSDELFDWE 926
            M    ++ D+L+   +VK+RWKV+RK+GGGGFGEIY+ LD  T+E VALK+ES++  KQVLKMEVAVLKKLQG  HVC+F+GCGRNDRFNYV M LQG+NLADLRR+Q    F+IST LRL  QIL+SI+ IH+ GFLHRDIKPSNF+MGR P +     MLDFGLARQ+   +  GD+R PR V GFRGTVRYAS+NAH NREMGRHDDLWS FYM+ E V G LPWRK+KDK+QVG IK+ ++H  +L+HLP EF   L HI SL YF  PDY+ L ++    ++  G+   + FDWE
Sbjct:    1 MSGGGEQPDILSVGILVKERWKVLRKIGGGGFGEIYDALDMLTRENVALKVESAQQPKQVLKMEVAVLKKLQGKDHVCRFIGCGRNDRFNYVVMQLQGRNLADLRRSQSRGTFTISTTLRLGKQILESIESIHSVGFLHRDIKPSNFAMGRFPSTCRKCFMLDFGLARQFT--NSCGDVRPPRAVAGFRGTVRYASINAHRNREMGRHDDLWSLFYMLVEFVVGQLPWRKIKDKEQVGSIKERYDHRLMLKHLPPEFSTFLDHISSLDYFTKPDYQLLTSVFDNSIKTFGVIESDPFDWE 298          
BLAST of Protein kinase vs. Ensembl Mouse
Match: Ttbk2 (tau tubulin kinase 2 [Source:MGI Symbol;Acc:MGI:2155779])

HSP 1 Score: 410.223 bits (1053), Expect = 5.540e-123
Identity = 185/300 (61.67%), Postives = 227/300 (75.67%), Query Frame = 3
Query:   27 MPSTKQETDLLNPSNIVKDRWKVIRKLGGGGFGEIYECLDSHTQEKVALKLESSRIAKQVLKMEVAVLKKLQGTAHVCKFLGCGRNDRFNYVAMTLQGKNLADLRRAQKNSAFSISTMLRLSAQILQSIQDIHNSGFLHRDIKPSNFSMGRLPLSSHTVVMLDFGLARQYILPDGNGDIRAPRPVTGFRGTVRYASVNAHMNREMGRHDDLWSAFYMMAEMVTGSLPWRKLKDKDQVGQIKQNFEHTQLLRHLPSEFKLLLSHIQSLTYFDAPDYEYLKNLIYQCMRRKGISSDELFDWE 926
            M    ++ D+L+   +VK+RWKV+RK+GGGGFGEIY+ LD  T+E VALK+ES++  KQVLKMEVAVLKKLQG  HVC+F+GCGRNDRFNYV M LQG+NLADLRR+Q    F+IST LRL  QIL+SI+ IH+ GFLHRDIKPSNF+MGR P +     MLDFGLARQ+   +  GD+R PR V GFRGTVRYAS+NAH NREMGRHDDLWS FYM+ E V G LPWRK+KDK+QVG IK+ ++H  +L+HLP EF   L HI SL YF  PDY+ L ++    ++  G+   + FDWE
Sbjct:    1 MSGGGEQPDILSVGILVKERWKVLRKIGGGGFGEIYDALDMLTRENVALKVESAQQPKQVLKMEVAVLKKLQGKDHVCRFIGCGRNDRFNYVVMQLQGRNLADLRRSQSRGTFTISTTLRLGKQILESIESIHSVGFLHRDIKPSNFAMGRFPSTCRKCFMLDFGLARQFT--NSCGDVRPPRAVAGFRGTVRYASINAHRNREMGRHDDLWSLFYMLVEFVVGQLPWRKIKDKEQVGSIKERYDHRLMLKHLPPEFSTFLDHISSLDYFTKPDYQLLTSVFDNSIKTFGVIESDPFDWE 298          
BLAST of Protein kinase vs. Ensembl Mouse
Match: Ttbk2 (tau tubulin kinase 2 [Source:MGI Symbol;Acc:MGI:2155779])

HSP 1 Score: 410.223 bits (1053), Expect = 5.540e-123
Identity = 185/300 (61.67%), Postives = 227/300 (75.67%), Query Frame = 3
Query:   27 MPSTKQETDLLNPSNIVKDRWKVIRKLGGGGFGEIYECLDSHTQEKVALKLESSRIAKQVLKMEVAVLKKLQGTAHVCKFLGCGRNDRFNYVAMTLQGKNLADLRRAQKNSAFSISTMLRLSAQILQSIQDIHNSGFLHRDIKPSNFSMGRLPLSSHTVVMLDFGLARQYILPDGNGDIRAPRPVTGFRGTVRYASVNAHMNREMGRHDDLWSAFYMMAEMVTGSLPWRKLKDKDQVGQIKQNFEHTQLLRHLPSEFKLLLSHIQSLTYFDAPDYEYLKNLIYQCMRRKGISSDELFDWE 926
            M    ++ D+L+   +VK+RWKV+RK+GGGGFGEIY+ LD  T+E VALK+ES++  KQVLKMEVAVLKKLQG  HVC+F+GCGRNDRFNYV M LQG+NLADLRR+Q    F+IST LRL  QIL+SI+ IH+ GFLHRDIKPSNF+MGR P +     MLDFGLARQ+   +  GD+R PR V GFRGTVRYAS+NAH NREMGRHDDLWS FYM+ E V G LPWRK+KDK+QVG IK+ ++H  +L+HLP EF   L HI SL YF  PDY+ L ++    ++  G+   + FDWE
Sbjct:    1 MSGGGEQPDILSVGILVKERWKVLRKIGGGGFGEIYDALDMLTRENVALKVESAQQPKQVLKMEVAVLKKLQGKDHVCRFIGCGRNDRFNYVVMQLQGRNLADLRRSQSRGTFTISTTLRLGKQILESIESIHSVGFLHRDIKPSNFAMGRFPSTCRKCFMLDFGLARQFT--NSCGDVRPPRAVAGFRGTVRYASINAHRNREMGRHDDLWSLFYMLVEFVVGQLPWRKIKDKEQVGSIKERYDHRLMLKHLPPEFSTFLDHISSLDYFTKPDYQLLTSVFDNSIKTFGVIESDPFDWE 298          
BLAST of Protein kinase vs. UniProt/SwissProt
Match: sp|Q8IMC6|ASATR_DROME (Tau-tubulin kinase homolog Asator OS=Drosophila melanogaster OX=7227 GN=Asator PE=1 SV=2)

HSP 1 Score: 431.024 bits (1107), Expect = 1.410e-129
Identity = 195/292 (66.78%), Postives = 231/292 (79.11%), Query Frame = 3
Query:   51 DLLNPSNIVKDRWKVIRKLGGGGFGEIYECLDSHTQEKVALKLESSRIAKQVLKMEVAVLKKLQGTAHVCKFLGCGRNDRFNYVAMTLQGKNLADLRRAQKNSAFSISTMLRLSAQILQSIQDIHNSGFLHRDIKPSNFSMGRLPLSSHTVVMLDFGLARQYILPDGNGDIRAPRPVTGFRGTVRYASVNAHMNREMGRHDDLWSAFYMMAEMVTGSLPWRKLKDKDQVGQIKQNFEHTQLLRHLPSEFKLLLSHIQSLTYFDAPDYEYLKNLIYQCMRRKGISSDELFDWE 926
            DLL P ++VK+RWKV+RK+GGGGFGEIYE  D  T+E+VALK+ES+R  KQVLKMEVAVLKKLQG  HVC+F+GCGRNDRFNYV M LQGKNLA+LRRAQ   AFS+ST LRL  QIL++I+ IH+ GFLHRDIKPSNFS+GRLP +   V MLDFGLARQY    G G++R PR   GFRGTVRYAS+NAH NREMGRHDDLWS FYM+ E V G LPWRK+KDK+QVG  K+ ++H  LL+HLPS+ K  L HIQSLTY D PDY  L  L  +CM+R+G+   + +DWE
Sbjct:  161 DLLQPGHVVKERWKVVRKIGGGGFGEIYEGQDLITREQVALKVESARQPKQVLKMEVAVLKKLQGKEHVCRFIGCGRNDRFNYVVMQLQGKNLAELRRAQPRGAFSLSTTLRLGLQILKAIESIHSVGFLHRDIKPSNFSVGRLPYNCRRVYMLDFGLARQYTT--GTGEVRCPRAAAGFRGTVRYASINAHRNREMGRHDDLWSLFYMLVEFVNGQLPWRKIKDKEQVGLTKEKYDHRILLKHLPSDLKQFLEHIQSLTYGDRPDYAMLIGLFERCMKRRGVKESDPYDWE 450          
BLAST of Protein kinase vs. UniProt/SwissProt
Match: sp|Q6PCN3|TTBK1_MOUSE (Tau-tubulin kinase 1 OS=Mus musculus OX=10090 GN=Ttbk1 PE=1 SV=3)

HSP 1 Score: 426.017 bits (1094), Expect = 2.239e-127
Identity = 188/295 (63.73%), Postives = 231/295 (78.31%), Query Frame = 3
Query:   42 QETDLLNPSNIVKDRWKVIRKLGGGGFGEIYECLDSHTQEKVALKLESSRIAKQVLKMEVAVLKKLQGTAHVCKFLGCGRNDRFNYVAMTLQGKNLADLRRAQKNSAFSISTMLRLSAQILQSIQDIHNSGFLHRDIKPSNFSMGRLPLSSHTVVMLDFGLARQYILPDGNGDIRAPRPVTGFRGTVRYASVNAHMNREMGRHDDLWSAFYMMAEMVTGSLPWRKLKDKDQVGQIKQNFEHTQLLRHLPSEFKLLLSHIQSLTYFDAPDYEYLKNLIYQCMRRKGISSDELFDWE 926
            ++ D+L  + +VKDRWKV++K+GGGGFGEIYE +D  T+E VALK+ES++  KQVLKMEVAVLKKLQG  HVC+F+GCGRN++FNYV M LQG+NLADLRR+Q    F++ST LRL  QIL+SI+ IH+ GFLHRDIKPSNF+MGRLP +     MLDFGLARQY   +  GD+R PR V GFRGTVRYASVNAH NREMGRHDDLWS FYM+ E   G LPWRK+KDK+QVG IK+ +EH  LL+H+PSEF L L HI SL YF  PDY+ + ++    M+ +GI+ +E FDWE
Sbjct:   19 EQADILPANYVVKDRWKVLKKIGGGGFGEIYEAMDLLTRENVALKVESAQQPKQVLKMEVAVLKKLQGKDHVCRFIGCGRNEKFNYVVMQLQGRNLADLRRSQPRGTFTLSTTLRLGKQILESIEAIHSVGFLHRDIKPSNFAMGRLPSTYRKCYMLDFGLARQYT--NTTGDVRPPRNVAGFRGTVRYASVNAHKNREMGRHDDLWSLFYMLVEFAVGQLPWRKIKDKEQVGMIKEKYEHRMLLKHMPSEFHLFLDHIASLDYFTKPDYQLIMSVFENSMKERGIAENEAFDWE 311          
BLAST of Protein kinase vs. UniProt/SwissProt
Match: sp|Q5TCY1|TTBK1_HUMAN (Tau-tubulin kinase 1 OS=Homo sapiens OX=9606 GN=TTBK1 PE=1 SV=2)

HSP 1 Score: 425.631 bits (1093), Expect = 3.578e-127
Identity = 188/295 (63.73%), Postives = 231/295 (78.31%), Query Frame = 3
Query:   42 QETDLLNPSNIVKDRWKVIRKLGGGGFGEIYECLDSHTQEKVALKLESSRIAKQVLKMEVAVLKKLQGTAHVCKFLGCGRNDRFNYVAMTLQGKNLADLRRAQKNSAFSISTMLRLSAQILQSIQDIHNSGFLHRDIKPSNFSMGRLPLSSHTVVMLDFGLARQYILPDGNGDIRAPRPVTGFRGTVRYASVNAHMNREMGRHDDLWSAFYMMAEMVTGSLPWRKLKDKDQVGQIKQNFEHTQLLRHLPSEFKLLLSHIQSLTYFDAPDYEYLKNLIYQCMRRKGISSDELFDWE 926
            ++ D+L  + +VKDRWKV++K+GGGGFGEIYE +D  T+E VALK+ES++  KQVLKMEVAVLKKLQG  HVC+F+GCGRN++FNYV M LQG+NLADLRR+Q    F++ST LRL  QIL+SI+ IH+ GFLHRDIKPSNF+MGRLP +     MLDFGLARQY   +  GD+R PR V GFRGTVRYASVNAH NREMGRHDDLWS FYM+ E   G LPWRK+KDK+QVG IK+ +EH  LL+H+PSEF L L HI SL YF  PDY+ + ++    M+ +GI+ +E FDWE
Sbjct:   19 EQADILPANYVVKDRWKVLKKIGGGGFGEIYEAMDLLTRENVALKVESAQQPKQVLKMEVAVLKKLQGKDHVCRFIGCGRNEKFNYVVMQLQGRNLADLRRSQPRGTFTLSTTLRLGKQILESIEAIHSVGFLHRDIKPSNFAMGRLPSTYRKCYMLDFGLARQYT--NTTGDVRPPRNVAGFRGTVRYASVNAHKNREMGRHDDLWSLFYMLVEFAVGQLPWRKIKDKEQVGMIKEKYEHRMLLKHMPSEFHLFLDHIASLDYFTKPDYQLIMSVFENSMKERGIAENEAFDWE 311          
BLAST of Protein kinase vs. UniProt/SwissProt
Match: sp|Q6IQ55|TTBK2_HUMAN (Tau-tubulin kinase 2 OS=Homo sapiens OX=9606 GN=TTBK2 PE=1 SV=2)

HSP 1 Score: 412.149 bits (1058), Expect = 7.828e-123
Identity = 186/304 (61.18%), Postives = 230/304 (75.66%), Query Frame = 3
Query:   27 MPSTKQETDLLNPSNIVKDRWKVIRKLGGGGFGEIYECLDSHTQEKVALKLESSRIAKQVLKMEVAVLKKLQGTAHVCKFLGCGRNDRFNYVAMTLQGKNLADLRRAQKNSAFSISTMLRLSAQILQSIQDIHNSGFLHRDIKPSNFSMGRLPLSSHTVVMLDFGLARQYILPDGNGDIRAPRPVTGFRGTVRYASVNAHMNREMGRHDDLWSAFYMMAEMVTGSLPWRKLKDKDQVGQIKQNFEHTQLLRHLPSEFKLLLSHIQSLTYFDAPDYEYLKNLIYQCMRRKGISSDELFDWETTSD 938
            M    ++ D+L+   +VK+RWKV+RK+GGGGFGEIY+ LD  T+E VALK+ES++  KQVLKMEVAVLKKLQG  HVC+F+GCGRNDRFNYV M LQG+NLADLRR+Q    F+IST LRL  QIL+SI+ IH+ GFLHRDIKPSNF+MGR P +     MLDFGLARQ+   +  GD+R PR V GFRGTVRYAS+NAH NREMGRHDDLWS FYM+ E V G LPWRK+KDK+QVG IK+ ++H  +L+HLP EF + L HI SL YF  PDY+ L ++    ++  G+   + FDWE T +
Sbjct:    1 MSGGGEQLDILSVGILVKERWKVLRKIGGGGFGEIYDALDMLTRENVALKVESAQQPKQVLKMEVAVLKKLQGKDHVCRFIGCGRNDRFNYVVMQLQGRNLADLRRSQSRGTFTISTTLRLGRQILESIESIHSVGFLHRDIKPSNFAMGRFPSTCRKCYMLDFGLARQFT--NSCGDVRPPRAVAGFRGTVRYASINAHRNREMGRHDDLWSLFYMLVEFVVGQLPWRKIKDKEQVGSIKERYDHRLMLKHLPPEFSIFLDHISSLDYFTKPDYQLLTSVFDNSIKTFGVIESDPFDWEKTGN 302          
BLAST of Protein kinase vs. UniProt/SwissProt
Match: sp|Q3UVR3|TTBK2_MOUSE (Tau-tubulin kinase 2 OS=Mus musculus OX=10090 GN=Ttbk2 PE=1 SV=1)

HSP 1 Score: 410.223 bits (1053), Expect = 3.875e-122
Identity = 185/300 (61.67%), Postives = 227/300 (75.67%), Query Frame = 3
Query:   27 MPSTKQETDLLNPSNIVKDRWKVIRKLGGGGFGEIYECLDSHTQEKVALKLESSRIAKQVLKMEVAVLKKLQGTAHVCKFLGCGRNDRFNYVAMTLQGKNLADLRRAQKNSAFSISTMLRLSAQILQSIQDIHNSGFLHRDIKPSNFSMGRLPLSSHTVVMLDFGLARQYILPDGNGDIRAPRPVTGFRGTVRYASVNAHMNREMGRHDDLWSAFYMMAEMVTGSLPWRKLKDKDQVGQIKQNFEHTQLLRHLPSEFKLLLSHIQSLTYFDAPDYEYLKNLIYQCMRRKGISSDELFDWE 926
            M    ++ D+L+   +VK+RWKV+RK+GGGGFGEIY+ LD  T+E VALK+ES++  KQVLKMEVAVLKKLQG  HVC+F+GCGRNDRFNYV M LQG+NLADLRR+Q    F+IST LRL  QIL+SI+ IH+ GFLHRDIKPSNF+MGR P +     MLDFGLARQ+   +  GD+R PR V GFRGTVRYAS+NAH NREMGRHDDLWS FYM+ E V G LPWRK+KDK+QVG IK+ ++H  +L+HLP EF   L HI SL YF  PDY+ L ++    ++  G+   + FDWE
Sbjct:    1 MSGGGEQPDILSVGILVKERWKVLRKIGGGGFGEIYDALDMLTRENVALKVESAQQPKQVLKMEVAVLKKLQGKDHVCRFIGCGRNDRFNYVVMQLQGRNLADLRRSQSRGTFTISTTLRLGKQILESIESIHSVGFLHRDIKPSNFAMGRFPSTCRKCFMLDFGLARQFT--NSCGDVRPPRAVAGFRGTVRYASINAHRNREMGRHDDLWSLFYMLVEFVVGQLPWRKIKDKEQVGSIKERYDHRLMLKHLPPEFSTFLDHISSLDYFTKPDYQLLTSVFDNSIKTFGVIESDPFDWE 298          
BLAST of Protein kinase vs. TrEMBL
Match: T1PJ51 (Protein kinase OS=Musca domestica OX=7370 GN=101890779 PE=2 SV=1)

HSP 1 Score: 435.261 bits (1118), Expect = 7.486e-139
Identity = 198/307 (64.50%), Postives = 239/307 (77.85%), Query Frame = 3
Query:   51 DLLNPSNIVKDRWKVIRKLGGGGFGEIYECLDSHTQEKVALKLESSRIAKQVLKMEVAVLKKLQGTAHVCKFLGCGRNDRFNYVAMTLQGKNLADLRRAQKNSAFSISTMLRLSAQILQSIQDIHNSGFLHRDIKPSNFSMGRLPLSSHTVVMLDFGLARQYILPDGNGDIRAPRPVTGFRGTVRYASVNAHMNREMGRHDDLWSAFYMMAEMVTGSLPWRKLKDKDQVGQIKQNFEHTQLLRHLPSEFKLLLSHIQSLTYFDAPDYEYLKNLIYQCMRRKGISSDELFDWETTSDIRQSVQSSSVT 971
            DLL   ++VK+RWKVIRK+GGGGFGEIYE  D  T+E+VALK+ES+R  KQVLKMEVAVLKKLQG  HVC+F+GCGRNDRFNYV M LQGKNLA+LRR+Q   AFS+ST LRL  QIL++I+ IH+ GFLHRDIKPSNFSMGRLPL+   V MLDFGLARQY    G G++R PR   GFRGTVRYAS+NAH NREMGRHDDLWS FYM+ E V G LPWRK+KDK+QVG  K+ ++H  LL+HLPS+FK  L HIQSLTY D PDY  L N+  +CM+R+G+   + +DWE    +  +   +++T
Sbjct:    5 DLLQAGHVVKERWKVIRKIGGGGFGEIYEGQDLITREQVALKVESARQPKQVLKMEVAVLKKLQGKEHVCRFIGCGRNDRFNYVVMQLQGKNLAELRRSQPKGAFSVSTTLRLGLQILRAIESIHSVGFLHRDIKPSNFSMGRLPLNCRKVYMLDFGLARQYT--TGTGEVRCPRAAAGFRGTVRYASINAHRNREMGRHDDLWSLFYMLVEFVNGQLPWRKIKDKEQVGLTKEKYDHRMLLKHLPSDFKQFLEHIQSLTYADRPDYAMLTNIFERCMKRRGVKESDPYDWEKVDAVSGTTVPTTIT 309          
BLAST of Protein kinase vs. TrEMBL
Match: A0A1I8P1Y9 (Protein kinase domain-containing protein OS=Stomoxys calcitrans OX=35570 GN=106086207 PE=4 SV=1)

HSP 1 Score: 432.95 bits (1112), Expect = 4.976e-138
Identity = 197/307 (64.17%), Postives = 239/307 (77.85%), Query Frame = 3
Query:   51 DLLNPSNIVKDRWKVIRKLGGGGFGEIYECLDSHTQEKVALKLESSRIAKQVLKMEVAVLKKLQGTAHVCKFLGCGRNDRFNYVAMTLQGKNLADLRRAQKNSAFSISTMLRLSAQILQSIQDIHNSGFLHRDIKPSNFSMGRLPLSSHTVVMLDFGLARQYILPDGNGDIRAPRPVTGFRGTVRYASVNAHMNREMGRHDDLWSAFYMMAEMVTGSLPWRKLKDKDQVGQIKQNFEHTQLLRHLPSEFKLLLSHIQSLTYFDAPDYEYLKNLIYQCMRRKGISSDELFDWETTSDIRQSVQSSSVT 971
            DLL   ++VK+RWKV+RK+GGGGFGEIYE  D  T+E+VALK+ES+R  KQVLKMEVAVLKKLQG  HVC+F+GCGRNDRFNYV M LQGKNLA+LRR+Q   AFS+ST LRL  QIL++I+ IH+ GFLHRDIKPSNFSMGRLPL+   V MLDFGLARQY    G G++R PR   GFRGTVRYAS+NAH NREMGRHDDLWS FYM+ E V G LPWRK+KDK+QVG  K+ ++H  LL+HLPS+FK  L HIQSLTY D PDY  L +L  +CM+R+G+   + +DWE    +  +   +++T
Sbjct:    5 DLLQAGHVVKERWKVVRKIGGGGFGEIYEGQDLITREQVALKVESARQPKQVLKMEVAVLKKLQGKEHVCRFIGCGRNDRFNYVVMQLQGKNLAELRRSQPKGAFSVSTTLRLGLQILRAIESIHSVGFLHRDIKPSNFSMGRLPLNCRRVYMLDFGLARQYT--TGTGEVRCPRAAAGFRGTVRYASINAHRNREMGRHDDLWSLFYMLVEFVNGQLPWRKIKDKEQVGLTKEKYDHRILLKHLPSDFKQFLEHIQSLTYADRPDYAMLTSLFERCMKRRGVKESDPYDWEKVDAVSGTTVPTTIT 309          
BLAST of Protein kinase vs. TrEMBL
Match: A0A267DEE2 (Protein kinase domain-containing protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig022436g3 PE=4 SV=1)

HSP 1 Score: 427.943 bits (1099), Expect = 2.398e-137
Identity = 199/306 (65.03%), Postives = 236/306 (77.12%), Query Frame = 3
Query:   27 MPSTKQETDLLNPSNIVKDRWKVIRKLGGGGFGEIYECLDSHTQEKVALKLESSRIAKQVLKMEVAVLKKLQGTAHVCKFLGCGRNDRFNYVAMTLQGKNLADLRRAQKNSAFSISTMLRLSAQILQSIQDIHNSGFLHRDIKPSNFSMGRLPLSSHTVVMLDFGLARQYILPDGNGDIRAPRPVTGFRGTVRYASVNAHMNREMGRHDDLWSAFYMMAEMVTGSLPWRKLKDKDQVGQIKQNFEHTQLLRHLPSEFKLLLSHIQSLTYFDAPDYEYLKNLIYQCMRRKGISSDELFDWETTSDIR 944
            M S   E DLL   ++VKDRW+V +K+GGGGFGEIYE  D   +E VALKLES++ AKQVLKMEVAVLKKLQG  HVC+FLGCGRNDRFNYV M LQGKNLA+LRR+Q   +F++ST +RL  QIL++I+ IH+ GFLHRDIKPSNFSMGR   +   V MLDFGLARQY   + +GD+RAPR   GFRGTVRYASVNAH NREMGRHDDLWS FYM+ E   G LPWRKLKDK+QVG+IK+ ++H+Q+LR+LPSEF+  L H+  L YFD PDY YL  L+ QC +RK I   E FDWE  S +R
Sbjct:    1 MNSVTSEADLLAVGSLVKDRWQVTKKIGGGGFGEIYEAQDVLNKEPVALKLESAKQAKQVLKMEVAVLKKLQGKDHVCRFLGCGRNDRFNYVVMELQGKNLAELRRSQPRGSFTVSTTVRLGRQILEAIEAIHSIGFLHRDIKPSNFSMGRGEPNCRKVFMLDFGLARQYT--NSDGDVRAPRVTAGFRGTVRYASVNAHQNREMGRHDDLWSLFYMLVEFACGQLPWRKLKDKEQVGRIKETYDHSQMLRYLPSEFRPFLEHVSKLAYFDKPDYRYLCGLLDQCAKRKSIRLSEPFDWEQASGLR 304          
BLAST of Protein kinase vs. TrEMBL
Match: A0A182SPC2 (Protein kinase domain-containing protein OS=Anopheles maculatus OX=74869 PE=4 SV=1)

HSP 1 Score: 428.713 bits (1101), Expect = 2.162e-135
Identity = 193/296 (65.20%), Postives = 236/296 (79.73%), Query Frame = 3
Query:   51 DLLNPSNIVKDRWKVIRKLGGGGFGEIYECLDSHTQEKVALKLESSRIAKQVLKMEVAVLKKLQGTAHVCKFLGCGRNDRFNYVAMTLQGKNLADLRRAQKNSAFSISTMLRLSAQILQSIQDIHNSGFLHRDIKPSNFSMGRLPLSSHTVVMLDFGLARQYILPDGNGDIRAPRPVTGFRGTVRYASVNAHMNREMGRHDDLWSAFYMMAEMVTGSLPWRKLKDKDQVGQIKQNFEHTQLLRHLPSEFKLLLSHIQSLTYFDAPDYEYLKNLIYQCMRRKGISSDELFDWETTSD 938
            DLL   ++VK+RWKV++K+GGGGFGEIYE  D  T+E+VALK+ES+R  KQVLKMEVAVLKKLQG  H+C+F+GCGRNDRFNYV M LQGKNLA+LRR+Q   AFS+ST LR+  QIL+SI+ IH+ GFLHRDIKPSNF++GRLPL+S  + MLDFGLARQY    G G++R PR   GFRGTVRYAS+NAH NREMGR DDLWS FYM+ E VTG LPWRK+KDK+QVG +K+ ++H  LL+HLPS+FK  L HIQSL Y D PDY  L +L  +CM+R+G+   + FDWE  +D
Sbjct:    3 DLLQAGHVVKERWKVLKKIGGGGFGEIYEGQDLITREQVALKVESARQPKQVLKMEVAVLKKLQGKEHICRFIGCGRNDRFNYVVMQLQGKNLAELRRSQARGAFSLSTTLRIGLQILKSIESIHSVGFLHRDIKPSNFAIGRLPLTSRRIYMLDFGLARQYT--TGTGEVRCPRAAAGFRGTVRYASLNAHKNREMGRQDDLWSLFYMLVEFVTGQLPWRKIKDKEQVGMLKEKYDHRLLLKHLPSDFKYFLEHIQSLNYADKPDYAMLISLFERCMKRRGVKETDPFDWENNAD 296          
BLAST of Protein kinase vs. TrEMBL
Match: A0A1B6LDH8 (Protein kinase domain-containing protein (Fragment) OS=Graphocephala atropunctata OX=36148 GN=g.26223 PE=4 SV=1)

HSP 1 Score: 433.721 bits (1114), Expect = 2.279e-135
Identity = 214/388 (55.15%), Postives = 266/388 (68.56%), Query Frame = 3
Query:   51 DLLNPSNIVKDRWKVIRKLGGGGFGEIYECLDSHTQEKVALKLESSRIAKQVLKMEVAVLKKLQGTAHVCKFLGCGRNDRFNYVAMTLQGKNLADLRRAQKNSAFSISTMLRLSAQILQSIQDIHNSGFLHRDIKPSNFSMGRLPLSSHTVVMLDFGLARQYILPDGNGDIRAPRPVTGFRGTVRYASVNAHMNREMGRHDDLWSAFYMMAEMVTGSLPWRKLKDKDQVGQIKQNFEHTQLLRHLPSEFKLLLSHIQSLTYFDAPDYEYLKNLIYQCMRRKGISSDELFDWE----TTSDIRQSVQSSSVT-----GGRNPHHNF----RKKPTSNIGSL------KDGDKS------NKNQSINIHQKSKVITNHKHKPLKSNDETG 1139
            DLL P ++VK+RWKV+RK+GGGGFGEIYE LD  T+E+VALK+ES+R  KQVLKMEVAVLKKLQG  HVC+F+GCGRNDRFNYV M LQGKNLA+LRRAQ   AFS+ST LRL  QIL++I  IH  GFLHRDIKPSNFS+GRLP +   V MLDFGLARQY      G++RAPR   GFRGTVRYAS+NAH N+EMGRHDDLWS FYM+ E V G LPWRK+KDK+QVG +K+ ++H  LL+HLPS+ +L L HIQSL Y D PDY  L  L+ +CM+R+G+   + +DWE    T + I Q+   +++T       RN + N     RK   + + +L       +GD +         Q+I I +     TN  + P    D  G
Sbjct:    5 DLLQPGHVVKERWKVMRKIGGGGFGEIYEGLDLVTKEQVALKVESARQPKQVLKMEVAVLKKLQGKDHVCRFIGCGRNDRFNYVVMQLQGKNLAELRRAQPRGAFSLSTTLRLGHQILKAIDSIHQVGFLHRDIKPSNFSIGRLPSNCRKVYMLDFGLARQYTT--ATGEVRAPRAAAGFRGTVRYASINAHKNKEMGRHDDLWSLFYMLVEFVNGQLPWRKIKDKEQVGLMKEKYDHRALLKHLPSDLRLFLEHIQSLEYSDKPDYAMLSLLLERCMKRRGVRESDPYDWEKPIVTQTQIPQTPAINTMTTPTPLSPRNNNQNIQPDNRKDNEAELDALCRRARKMEGDTTQVTPTNTDKQAITIDRNCNATTNQDNTPPVPGDVAG 390          
BLAST of Protein kinase vs. Ensembl Cavefish
Match: ttbk1a (tau tubulin kinase 1a [Source:ZFIN;Acc:ZDB-GENE-100609-4])

HSP 1 Score: 417.927 bits (1073), Expect = 5.117e-131
Identity = 186/302 (61.59%), Postives = 237/302 (78.48%), Query Frame = 3
Query:   27 MPSTKQETDLLNPSNIVKDRWKVIRKLGGGGFGEIYECLDSHTQEKVALKLESSRIAKQVLKMEVAVLKKLQGTAHVCKFLGCGRNDRFNYVAMTLQGKNLADLRRAQKNSAFSISTMLRLSAQILQSIQDIHNSGFLHRDIKPSNFSMGRLPLSSHTVVMLDFGLARQYILPDGNGDIRAPRPVTGFRGTVRYASVNAHMNREMGRHDDLWSAFYMMAEMVTGSLPWRKLKDKDQVGQIKQNFEHTQLLRHLPSEFKLLLSHIQSLTYFDAPDYEYLKNLIYQCMRRKGISSDELFDWETT 932
            M  + ++ D+L P+ +VKDRWKV++K+GGGGFGEIYE +D  T+E VALK+ES++  KQVLKMEVAVLKKLQG  HVCKF+GCGRND+FNYV M LQG+NLADLRR+Q    F++ST LRL  QIL++I+ IH+ GFLHRDIKPSNF+MGRLP +     MLDFGLARQY   + NG++R PR V GFRGTVRYASVNAH N+EMGRHDDLWS FYM+ E   G LPWRK+KDK+QVGQ+K+ ++H  LL+H+PSEF + L H+ +L Y+  PDY+ L ++    M+ + I+ +EL+DWE T
Sbjct:   30 MNGSSEQQDILPPNCMVKDRWKVLKKIGGGGFGEIYEAVDLLTRENVALKVESAQQPKQVLKMEVAVLKKLQGKNHVCKFIGCGRNDKFNYVVMQLQGRNLADLRRSQPRGTFTMSTTLRLGKQILEAIEAIHSVGFLHRDIKPSNFAMGRLPSTVRKCYMLDFGLARQYT--NTNGEVRPPRTVAGFRGTVRYASVNAHKNKEMGRHDDLWSLFYMLVEFAVGQLPWRKIKDKEQVGQVKERYDHRMLLKHMPSEFHVFLDHVLALDYYTKPDYQLLMSVFENSMKERIITENELYDWEKT 329          
BLAST of Protein kinase vs. Ensembl Cavefish
Match: ttbk1b (tau tubulin kinase 1b [Source:ZFIN;Acc:ZDB-GENE-100609-5])

HSP 1 Score: 413.69 bits (1062), Expect = 2.114e-129
Identity = 188/300 (62.67%), Postives = 232/300 (77.33%), Query Frame = 3
Query:   27 MPSTKQETDLLNPSNIVKDRWKVIRKLGGGGFGEIYECLDSHTQEKVALKLESSRIAKQVLKMEVAVLKKLQGTAHVCKFLGCGRNDRFNYVAMTLQGKNLADLRRAQKNSAFSISTMLRLSAQILQSIQDIHNSGFLHRDIKPSNFSMGRLPLSSHTVVMLDFGLARQYILPDGNGDIRAPRPVTGFRGTVRYASVNAHMNREMGRHDDLWSAFYMMAEMVTGSLPWRKLKDKDQVGQIKQNFEHTQLLRHLPSEFKLLLSHIQSLTYFDAPDYEYLKNLIYQCMRRKGISSDELFDWE 926
            M    ++ D+L P+ +VK+RWKV++K+GGGGFGEIYE LD  T+E VALK+ES++  KQVLKMEVAVLKKLQG  HVCKF+GCGRN++FNYV M LQG+NLADLRR+Q    FS+ST LRL  QIL+SI+ IH+ GFLHRDIKPSNF+MGRLP +     MLDFGLARQY   + NG++R PR V GFRGTVRYASVNAH N+EMGRHDDLWS FYM+ E   G LPWRK+KDK+QVGQIK+ +EH  LL+H+PSEF + L H+  L Y+  PDY  L ++    M+ + I+ +E FDWE
Sbjct:   14 MNGAGEQVDILPPNCMVKERWKVLKKIGGGGFGEIYEALDLLTRENVALKVESAQQPKQVLKMEVAVLKKLQGKNHVCKFIGCGRNEKFNYVVMQLQGRNLADLRRSQPRGTFSMSTTLRLGKQILESIEAIHSVGFLHRDIKPSNFAMGRLPSTYRKCYMLDFGLARQYT--NTNGEVRPPRTVAGFRGTVRYASVNAHKNKEMGRHDDLWSLFYMLVEFTVGQLPWRKIKDKEQVGQIKERYEHKMLLKHMPSEFYIFLDHVLGLDYYTKPDYLLLMSVFENSMKEREITENEPFDWE 311          
BLAST of Protein kinase vs. Ensembl Cavefish
Match: ttbk2b (tau tubulin kinase 2b [Source:ZFIN;Acc:ZDB-GENE-030131-8246])

HSP 1 Score: 386.726 bits (992), Expect = 4.117e-117
Identity = 176/302 (58.28%), Postives = 226/302 (74.83%), Query Frame = 3
Query:   27 MPSTKQETDLLNPSNIVKDRWKVIRKLGGGGFGEIYECLDSHTQEKVALKLESSRIAKQVLKMEVAVLKKLQGTAHVCKFLGCGRNDRFNYVAMTLQGKNLADLRRAQKNSAFSISTMLRLSAQILQSIQDIHNSGFLHRDIKPSNFSMGRLPLSSHTVVMLDFGLARQYILPDGNGDIRAPRPVTGFRGTVRYASVNAHMNREMGRHDDLWSAFYMMAEMVTGSLPWRKLKDKDQVGQIKQNFEHTQLLRHLPSEFKLLLSHIQSLTYFDAPDYEYLKNLIYQCMRRKGISSDELFDWETT 932
            M    ++ D+L+  N+V++RW+V  K+GGGGFGEIYE LD   Q  VALK+ES++  KQVLKMEVAVLK+LQ   HVC+F+GCGRNDRFNYV M LQG+NLADLRR      FS+ST LRL  QIL++I+ IH+ GFLHRDIKPSNF+MGRL  +  T  MLDFGLARQ+   +   ++R PRPV GFRGTVRYAS+NAH N+EMGRHDDLWS FYM+ E + G LPWRK+KDK+QVG +K+ ++H  +L+HLPSEF + L HI +L YF  PDY+ L ++  + M+   +  ++ +DWE T
Sbjct:    1 MSGAAEQADILSVGNVVRERWRV--KIGGGGFGEIYEVLDQLNQCNVALKVESAQQPKQVLKMEVAVLKRLQ-KDHVCRFVGCGRNDRFNYVVMELQGRNLADLRRTMSQGTFSVSTTLRLGRQILEAIESIHSVGFLHRDIKPSNFAMGRLSSTCRTCYMLDFGLARQFT--NSCQEVRPPRPVAGFRGTVRYASINAHKNKEMGRHDDLWSLFYMLVEFMVGQLPWRKVKDKEQVGNLKETYDHHLMLKHLPSEFIVFLEHISNLDYFTKPDYQLLMSVFEKSMKSYNVMENDPYDWERT 297          
BLAST of Protein kinase vs. Ensembl Cavefish
Match: ttbk2b (tau tubulin kinase 2b [Source:ZFIN;Acc:ZDB-GENE-030131-8246])

HSP 1 Score: 330.487 bits (846), Expect = 3.117e-102
Identity = 160/302 (52.98%), Postives = 205/302 (67.88%), Query Frame = 3
Query:   27 MPSTKQETDLLNPSNIVKDRWKVIRKLGGGGFGEIYECLDSHTQEKVALKLESSRIAKQVLKMEVAVLKKLQGTAHVCKFLGCGRNDRFNYVAMTLQGKNLADLRRAQKNSAFSISTMLRLSAQILQSIQDIHNSGFLHRDIKPSNFSMGRLPLSSHTVVMLDFGLARQYILPDGNGDIRAPRPVTGFRGTVRYASVNAHMNREMGRHDDLWSAFYMMAEMVTGSLPWRKLKDKDQVGQIKQNFEHTQLLRHLPSEFKLLLSHIQSLTYFDAPDYEYLKNLIYQCMRRKGISSDELFDWETT 932
            M    ++ D+L+  N+V++RW+VI+K+GGGGFGEIYE LD   Q  VALK+ES++  KQVLKMEVAVLK+LQG  HVC+F+GCGRNDRFNYV M LQG+NLADLRR      FS+ST LRL  QIL++I+ IH+ GFLHRDIKP                                     PRPV GFRGTVRYAS+NAH N+EMGRHDDLWS FYM+ E + G LPWRK+KDK+QVG +K+ ++H  +L+HLPSEF + L HI +L YF  PDY+ L ++  + M+   +  ++ +DWE T
Sbjct:    1 MSGAAEQADILSVGNVVRERWRVIKKIGGGGFGEIYEVLDQLNQCNVALKVESAQQPKQVLKMEVAVLKRLQGKDHVCRFVGCGRNDRFNYVVMELQGRNLADLRRTMSQGTFSVSTTLRLGRQILEAIESIHSVGFLHRDIKP-------------------------------------PRPVAGFRGTVRYASINAHKNKEMGRHDDLWSLFYMLVEFMVGQLPWRKVKDKEQVGNLKETYDHHLMLKHLPSEFIVFLEHISNLDYFTKPDYQLLMSVFEKSMKSYNVMENDPYDWERT 265          
BLAST of Protein kinase vs. Ensembl Cavefish
Match: csnk1db (casein kinase I [Source:NCBI gene;Acc:103030301])

HSP 1 Score: 174.866 bits (442), Expect = 5.533e-48
Identity = 106/290 (36.55%), Postives = 154/290 (53.10%), Query Frame = 3
Query:   75 VKDRWKVIRKLGGGGFGEIYECLDSHTQEKVALKLESSRIAKQVLKMEVAVLKKLQGTAHVCKFLGCGRNDRFNYVAMTLQGKNLADLRRAQKNSAFSISTMLRLSAQILQSIQDIHNSGFLHRDIKPSNFSMGRLPLSSHTVVMLDFGLARQYILPDGNGDIRAP-RPVTGFRGTVRYASVNAHMNREMGRHDDLWSAFYMMAEMVTGSLPWRKLKDK------DQVGQIKQNFEHTQLLRHLPSEFKLLLSHIQSLTYFDAPDYEYLKNLIYQCMRRKGISSDELFDW 923
            V +R+++ RK+G G FG+IY   D    E+VA+KLE  +     L +E  + K +QG   +     CG    +N + M L G +L DL     +  FS+ T+L L+ Q++  I+ IH+  F+HRD+KP NF MG L    + V ++DFGLA++Y   D       P R      GT RYAS+N H+  E  R DDL S  Y++     GSLPW+ LK        +++ + K +     L +  PSEF   L+  +SL + D PDY YL+ L      R+G S D +FDW
Sbjct:    5 VGNRYRLGRKIGSGSFGDIYLGTDISVGEEVAIKLECVKTKHPQLHIESKIYKMMQGGVGIPTIKWCGAEGDYNVMVMELLGPSLEDLFNFC-SRKFSLKTVLLLADQMISRIEYIHSKNFIHRDVKPDNFLMG-LGKKGNLVYIIDFGLAKKY--RDARTHQHIPYRENKNLTGTARYASINTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKKMSTPIEVLCKGYPSEFATYLNFCRSLRFDDKPDYSYLRQLFRNLFHRQGFSYDYVFDW 290          
BLAST of Protein kinase vs. Ensembl Sea Lamprey
Match: ENSPMAT00000004926.1 (pep scaffold:Pmarinus_7.0:GL480178:196:11423:1 gene:ENSPMAG00000004461.1 transcript:ENSPMAT00000004926.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 307.76 bits (787), Expect = 4.413e-97
Identity = 134/240 (55.83%), Postives = 180/240 (75.00%), Query Frame = 3
Query:  252 HVCKFLGCGRNDRFNYVAMTLQGKNLADLRRAQKNSAFSISTMLRLSAQILQSIQDIHNSGFLHRDIKPSNFSMGRLPLSSHTVVMLDFGLARQYILPDGNGDIRAPRPVTGFRGTVRYASVNAHMNREMGRHDDLWSAFYMMAEMVTGSLPWRKLKDKDQVGQIKQNFEHTQLLRHLPSEFKLLLSHIQSLTYFDAPDYEYLKNLIYQCMRRKGISSDELFDWETTSDIRQSVQSSSVT 971
            HVC+F+GCGRND+FNYV M LQG+NLADLRR+Q    FS+ST LRL  Q+L++I+ IH  GFLHRDIKPSNF+MGRLP ++H   MLD+GLARQY   + +G++R PR V GFRGTVRYAS+NAH N+EMGRHDDLWS FYM+ E   G LPWRK+KDK+QVG IK+ ++H  LLRH+P++F + L H+ +L Y   P+Y+ + +     MR + I+ +E +DWE    + +S+ S++ +
Sbjct:    3 HVCRFIGCGRNDKFNYVVMQLQGRNLADLRRSQPRGTFSLSTTLRLGRQMLEAIESIHAVGFLHRDIKPSNFAMGRLPSTTHKCFMLDYGLARQYT--NSSGEVRPPRAVAGFRGTVRYASINAHRNKEMGRHDDLWSLFYMLVEFTVGQLPWRKIKDKEQVGLIKERYDHRLLLRHMPTDFHIFLDHVSTLDYCTRPNYQSIHSCALHIMRERSITENEPYDWE-KGGLEESLASTTTS 239          
BLAST of Protein kinase vs. Ensembl Sea Lamprey
Match: ENSPMAT00000008477.1 (pep scaffold:Pmarinus_7.0:GL482342:316:9736:-1 gene:ENSPMAG00000007664.1 transcript:ENSPMAT00000008477.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 168.318 bits (425), Expect = 5.895e-46
Identity = 104/293 (35.49%), Postives = 155/293 (52.90%), Query Frame = 3
Query:   75 VKDRWKVIRKLGGGGFGEIYEC-LDSHTQEKVALKLESSRIAKQVLKMEVAVLKKLQGTAHVCKFLGCGRNDRFNYVAMTLQGKNLADLRRAQKNSAFSISTMLRLSAQILQSIQDIHNSGFLHRDIKPSNFSMGRLPLSSHTVVMLDFGLARQYILPDGNGDIRAP-RPVTGFRGTVRYASVNAHMNREMGRHDDLWSAFYMMAEMVTGSLPWRKLKDK------DQVGQIKQNFEHTQLLRHLPSEFKLLLSHIQSLTYFDAPDYEYLKNLIYQCMRRKGISSDELFDWET 929
            + +++++ RK+G G FG+IY    +  T E+VA+KLE  +     L +E  + K LQG   +     CG    +N + M L G ++ DL     +  FS+ T+L L+ Q++  I+ +H+  F+HRDIKP NF MG L    + V ++D GLA++Y   D       P R      GT RYAS+N H+  E  R DDL S  Y++     GSLPW+ LK        +++ + K +     L +  PSEF   L+  +SL + D PDY YL+ L      R+G S D +FDW T
Sbjct:    5 IGNKYRLGRKIGSGSFGDIYLVGTNIATGEEVAIKLECVKTKHPQLHIESKIYKLLQGGVGIPVIKWCGAEGDYNVMVMELLGPSMEDLFNFC-SRKFSLKTVLLLADQMISRIEYLHSKNFIHRDIKPDNFLMG-LGKKGNLVYIIDLGLAKKY--RDSRTHQHIPYRENKNLTGTARYASINTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKKMSTPIEMLCKTYPSEFATYLNFCRSLRFDDKPDYSYLRQLFRNLFHRQGFSYDYVFDWNT 293          
BLAST of Protein kinase vs. Ensembl Sea Lamprey
Match: csnk1g2a (casein kinase 1, gamma 2a [Source:ZFIN;Acc:ZDB-GENE-030131-6445])

HSP 1 Score: 167.933 bits (424), Expect = 3.407e-45
Identity = 99/294 (33.67%), Postives = 156/294 (53.06%), Query Frame = 3
Query:   72 IVKDRWKVIRKLGGGGFGEIYECLDSHTQEKVALKLESSRIAKQVLKMEVAVLKKL---QGTAHVCKFLGCGRNDRFNYVAMTLQGKNLADLRRAQKNSAFSISTMLRLSAQILQSIQDIHNSGFLHRDIKPSNFSMGRLPLS-SHTVVMLDFGLARQYILPDGNGDIRAPRPVTGFRGTVRYASVNAHMNREMGRHDDLWSAFYMMAEMVTGSLPWRKLKDK------DQVGQIKQNFEHTQLLRHLPSEFKLLLSHIQSLTYFDAPDYEYLKNLIYQCMRRKGISSDELFDW 923
            +V   ++V +K+G G FGE+    + +T E VA+KLE  +     L +E    K+L   +G   V  F  CG+   +N + + L G +L DL     N  F++ T+L ++ Q+L  ++ +H+   ++RD+KP NF +GR   +  H + ++DFGLA++YI P+    I   R      GT RY S+N H+ +E  R DDL +  +M    + GSLPW+ LK         ++G  K+      L  + P E    L +++ L +F+ PDYEY++NL      RKG S D  FDW
Sbjct:   33 MVGPNFRVGKKIGCGNFGELRLGKNLYTNEYVAIKLEPMKSRAPQLHLEYRFYKQLGNAEGVPQVYYFGPCGK---YNAMVLELLGPSLEDLFDLC-NRTFTLKTVLMIAIQLLTRMEYVHSRNLIYRDVKPENFLIGRQSTNKQHIIHIIDFGLAKEYIDPETKKHIPY-REHKSLTGTARYMSINTHLGKEQSRRDDLEALGHMFMYFLRGSLPWQGLKADTLKERYQKIGDTKRATPIEVLCENFPEEMATYLRYVRRLDFFERPDYEYMRNLFMDLFERKGYSFDYEFDW 321          
BLAST of Protein kinase vs. Ensembl Sea Lamprey
Match: csnk1g1 (casein kinase 1, gamma 1 [Source:NCBI gene;Acc:494092])

HSP 1 Score: 125.176 bits (313), Expect = 2.099e-32
Identity = 76/221 (34.39%), Postives = 122/221 (55.20%), Query Frame = 3
Query:   72 IVKDRWKVIRKLGGGGFGEIYECLDSHTQEKVALKLESSRIAKQVLKMEVAVLKKL---QGTAHVCKFLGCGRNDRFNYVAMTLQGKNLADLRRAQKNSAFSISTMLRLSAQILQSIQDIHNSGFLHRDIKPSNFSMGRLPLSSH-TVVMLDFGLARQYILPDGNGDIRAPRPVTGFRGTVRYASVNAHMNREMGRHDDLWSAFYMMAEMVTGSLPWRKLK 722
            +V   ++V +K+G G FGE+    + +T E VA+KLE  +     L +E    K+L   +G   V  F  CG+   +N + + L G +L DL     +  FS+ T+L ++ Q++  ++ +H+   ++RD+KP NF +GR   S H  + ++DFGLA++YI P+    I   R      GT RY S+N H+ +E  R DDL +  +M    + GSLPW+ LK
Sbjct:   27 MVGPNFRVGKKIGCGNFGELRLGKNLYTNEYVAIKLEPMKSRAPQLHLEYRFYKQLGNAEGVPQVYYFGPCGK---YNAMVLELLGPSLEDLFDLC-DRTFSLKTVLMIAMQLISRMEYVHSRSLIYRDVKPENFLVGRQGTSKHHNIHIIDFGLAKEYIDPETKKHIPY-REHKSLTGTARYMSINTHLGKEQSRRDDLEALGHMFMYFLRGSLPWQGLK 242          
BLAST of Protein kinase vs. Ensembl Sea Lamprey
Match: ENSPMAT00000001691.1 (pep scaffold:Pmarinus_7.0:GL476581:539457:546336:1 gene:ENSPMAG00000001522.1 transcript:ENSPMAT00000001691.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 112.849 bits (281), Expect = 1.299e-28
Identity = 69/190 (36.32%), Postives = 106/190 (55.79%), Query Frame = 3
Query:   72 IVKDRWKVIRKLGGGGFGEIYECLDSHTQEKVALKLESSRIAKQVLKMEVAVLKKLQGTAHVCKFLGCGRNDRFNYVAMTLQGKNLADLRRAQKNSAFSISTMLRLSAQILQSIQDIHNSGFLHRDIKPSNFSMGRLPLSSHTVVMLDFGLARQYILPDGNGDIRAP-RPVTGFRGTVRYASVNAHMNRE 638
            IV  +++++RK+G G FG+IY  ++    E+VA+KLES +     L  E  + K LQG   +      G+   +N + M L G +L DL     +  F++ T+L L+ Q++  I+ +HN  F+HRDIKP NF MG +    + + ++DFGLA++Y   D       P R      GT RYAS+NAH+  E
Sbjct:   12 IVGGKYRLVRKIGSGSFGDIYLAINITNGEEVAVKLESQKARHPQLLYESKLYKILQGGVGIPHIRWYGQEKDYNVLVMDLLGPSLEDLFNFC-SRRFTMKTVLMLADQMISRIEYVHNKNFIHRDIKPDNFLMG-IGRHCNKLFLIDFGLAKKY--RDNRTRQHIPYREDKNLTGTARYASINAHLGIE 197          
BLAST of Protein kinase vs. Ensembl Yeast
Match: HRR25 (Conserved casein kinase; regulates diverse events including: vesicular traffic, DNA repair, the CVT pathway, monopolar attachment of sister kinetochores at meiosis I, and ribosomal subunit biogenesis; monopolin subunit; binds the RNAPII CTD; phosphorylates COPII coat subunits; interacts with Sit4p phosphatase; antagonizes calcineurin signaling, reducing nuclear accumulation of Crz1p; phosphorylates Dsn1p, the kinetochore receptor for monopolin; homolog of mammalian CK1delta [Source:SGD;Acc:S000006125])

HSP 1 Score: 157.918 bits (398), Expect = 2.467e-41
Identity = 103/290 (35.52%), Postives = 149/290 (51.38%), Query Frame = 3
Query:   75 VKDRWKVIRKLGGGGFGEIYECLDSHTQEKVALKLESSRIAKQVLKMEVAVLKKLQGTAHVCKFLGCGRNDRFNYVAMTLQGKNLADLRRAQKNSAFSISTMLRLSAQILQSIQDIHNSGFLHRDIKPSNFSMGRLPLSSHTVVMLDFGLARQYILPDGNGDIRAP-RPVTGFRGTVRYASVNAHMNREMGRHDDLWSAFYMMAEMVTGSLPWRKLKDK------DQVGQIKQNFEHTQLLRHLPSEFKLLLSHIQSLTYFDAPDYEYLKNLIYQCMRRKGISSDELFDW 923
            V  ++++ RK+G G FG+IY   +  + E+VA+KLES R     L  E  V + L G   +      GR   +N + + L G +L DL     +  FS  T++ L+ Q+   IQ IH   F+HRDIKP NF MG +     TV ++DFGL+++Y   D N     P R      GT RYASVN H+  E  R DDL S  Y++     GSLPW+ LK        D++ + K N     L   LP EF+  +++ ++L + + PDY +L  L      +    +D LFDW
Sbjct:    5 VGRKFRIGRKIGSGSFGDIYHGTNLISGEEVAIKLESIRSRHPQLDYESRVYRYLSGGVGIPFIRWFGREGEYNAMVIDLLGPSLEDLFNYC-HRRFSFKTVIMLALQMFCRIQYIHGRSFIHRDIKPDNFLMG-VGRRGSTVHVIDFGLSKKY--RDFNTHRHIPYRENKSLTGTARYASVNTHLGIEQSRRDDLESLGYVLIYFCKGSLPWQGLKATTKKQKYDRIMEKKLNVSVETLCSGLPLEFQEYMAYCKNLKFDEKPDYLFLARLFKDLSIKLEYHNDHLFDW 290          
BLAST of Protein kinase vs. Ensembl Yeast
Match: YCK1 (Palmitoylated plasma membrane-bound casein kinase I (CK1) isoform; shares redundant functions with Yck2p in morphogenesis, proper septin assembly, endocytic trafficking, and glucose sensing; stabilized by Sod1p binding in the presence of glucose and oxygen, causing glucose repression of respiratory metabolism; involved in the phosphorylation and regulation of glucose sensor Rgt2p; YCK1 has a paralog, YCK2, that arose from the whole genome duplication [Source:SGD;Acc:S000001177])

HSP 1 Score: 146.362 bits (368), Expect = 2.780e-37
Identity = 90/300 (30.00%), Postives = 154/300 (51.33%), Query Frame = 3
Query:   66 SNIVKDRWKVIRKLGGGGFGEIYECLDSHTQEKVALKLESSRIAKQVLKMEVAVLKKLQGTAHVCKFLGCGRNDRFNYVAMTLQGKNLADLRRAQKNSAFSISTMLRLSAQILQSIQDIHNSGFLHRDIKPSNFSMGRLP-LSSHTVVMLDFGLARQYILPDGNGDIRAPRPVTGFRGTVRYASVNAHMNREMGRHDDLWSAFYMMAEMVTGSLPWRKLKDK------DQVGQIKQNFEHTQLLRHLPSEFKLLLSHIQSLTYFDAPDYEYLKNLIYQCMRRKGISSDELFDWETTSDIR 944
            S IV   +K+ +K+G G FG ++E  +      VA+K E  +     L+ E    K L GT ++      G+    N + + L G +L DL        FS+ T+++++ Q++  I+D+H    ++RDIKP NF +GR     ++ + ++DFG+A+QY  P     I   R      GT RY S+N H+ RE  R DD+ +  ++    + G LPW+ LK        +++G+ K++     L + LP +F   L  ++SL++ + PDYE  + L+   +   G ++D  +DW   +D R
Sbjct:   62 STIVGLHYKIGKKIGEGSFGVLFEGTNMINGVPVAIKFEPRKTEAPQLRDEYKTYKILNGTPNIPYAYYFGQEGLHNILVIDLLGPSLEDLFD-WCGRKFSVKTVVQVAVQMITLIEDLHAHDLIYRDIKPDNFLIGRPGQPDANNIHLIDFGMAKQYRDPKTKQHIPY-REKKSLSGTARYMSINTHLGREQSRRDDMEALGHVFFYFLRGHLPWQGLKAPNNKQKYEKIGEKKRSTNVYDLAQGLPVQFGRYLEIVRSLSFEECPDYEGYRKLLLSVLDDLGETADGQYDWMKLNDGR 359          
BLAST of Protein kinase vs. Ensembl Yeast
Match: YCK2 (Palmitoylated plasma membrane-bound casein kinase I (CK1) isoform; shares redundant functions with Yck1p in morphogenesis, proper septin assembly, endocytic trafficking, and glucose sensing; stabilized by Sod1p binding in the presence of glucose and oxygen, causing glucose repression of respiratory metabolism; involved in the phosphorylation and regulation of glucose sensor Rgt2p; YCK2 has a paralog, YCK1, that arose from the whole genome duplication [Source:SGD;Acc:S000005098])

HSP 1 Score: 142.51 bits (358), Expect = 6.516e-36
Identity = 91/298 (30.54%), Postives = 152/298 (51.01%), Query Frame = 3
Query:   66 SNIVKDRWKVIRKLGGGGFGEIYECLDSHTQEKVALKLESSRIAKQVLKMEVAVLKKLQGTAHVCKFLGCGRNDRFNYVAMTLQGKNLADL-----RRAQKNSAFSISTMLRLSAQILQSIQDIHNSGFLHRDIKPSNFSMGRLP-LSSHTVVMLDFGLARQYILPDGNGDIRAPRPVTGFRGTVRYASVNAHMNREMGRHDDLWSAFYMMAEMVTGSLPWRKLKDK------DQVGQIKQNFEHTQLLRHLPSEFKLLLSHIQSLTYFDAPDYEYLKNLIYQCMRRKGISSDELFDW 923
            S IV   +K+ +K+G G FG ++E  +      VA+K E  +     LK E    K L GT  + +    G+    N + + L G +L DL     RR      FS+ T+++++ Q++  I+D+H    ++RDIKP NF +GR     ++ V ++DFG+A+QY  P     I   R      GT RY S+N H+ RE  R DD+ +  ++    + G LPW+ LK        +++G+ K+      L + LP +F   L  +++L++ + PDYE  + L+   +   G ++D  +DW
Sbjct:   69 STIVGLHYKIGKKIGEGSFGVLFEGTNMINGLPVAIKFEPRKTEAPQLKDEYRTYKILAGTPGIPQEYYFGQEGLHNILVIDLLGPSLEDLFDWCGRR------FSVKTVVQVAVQMITLIEDLHAHDLIYRDIKPDNFLIGRPGQPDANKVHLIDFGMAKQYRDPKTKQHIPY-REKKSLSGTARYMSINTHLGREQSRRDDMEAMGHVFFYFLRGQLPWQGLKAPNNKQKYEKIGEKKRLTNVYDLAQGLPIQFGRYLEIVRNLSFEETPDYEGYRMLLLSVLDDLGETADGQYDW 359          
BLAST of Protein kinase vs. Ensembl Yeast
Match: YCK3 (Palmitoylated vacuolar membrane-localized casein kinase I isoform; negatively regulates vacuole fusion during hypertonic stress via phosphorylation of Vps41p; shares essential functions with Hrr25p; regulates vesicle fusion in AP-3 pathway [Source:SGD;Acc:S000000925])

HSP 1 Score: 124.02 bits (310), Expect = 6.435e-30
Identity = 95/326 (29.14%), Postives = 145/326 (44.48%), Query Frame = 3
Query:   72 IVKDRWKVIRKLGGGGFGEIYE-------C-------LDSH---TQEKVALKLESSRIAKQVLKMEVAVLKKLQGTAHVCKFLGCGRNDRFNYVAMTLQGKNLADLRRAQKNSAFSISTMLRLSAQILQSIQDIHNSGFLHRDIKPSNFSM---------GRLPLSSHT--------VVMLDFGLARQYILPDGNGDIRAPRPVTGFRGTVRYASVNAHMNREMGRHDDLWSAFYMMAEMVTGSLPWRKLKDK------DQVGQIKQNFEHTQLLRH--LPSEFKLLLSHIQSLTYFDAPDYEYLKNLIYQCMRRKGISSDELFDW 923
            IV   + V  K+G G FG I+E       C        DS      E VA+K E        L+ E    + L G   +      G+    N + + L G +L DL        FS+ T   ++ Q++  ++ IH+   ++RDIKP NF +         G++  S  +        + M+DFG+A+QY  P     I   R      GT RY S+N H  RE  R DDL S  ++    + GSLPW+ LK        +++G  KQ      LL +  +P +F   L + +SL + + PDY+YL +L+   +R   +  D  +DW
Sbjct:    9 IVGIHYAVGPKIGEGSFGVIFEGENILHSCQAQTGSKRDSSIIMANEPVAIKFEPRHSDAPQLRDEFRAYRILNGCVGIPHAYYFGQEGMHNILIIDLLGPSLEDLFE-WCGRKFSVKTTCMVAKQMIDRVRAIHDHDLIYRDIKPDNFLISQYQRISPEGKVIKSCASSSNNDPNLIYMVDFGMAKQYRDPRTKQHIPY-RERKSLSGTARYMSINTHFGREQSRRDDLESLGHVFFYFLRGSLPWQGLKAPNNKLKYEKIGMTKQKLNPDDLLLNNAIPYQFATYLKYARSLKFDEDPDYDYLISLMDDALRLNDLKDDGHYDW 332          
BLAST of Protein kinase vs. Ensembl Yeast
Match: HOG1 (Mitogen-activated protein kinase involved in osmoregulation; controls global reallocation of RNAPII during osmotic shock; mediates recruitment/activation of RNAPII at Hot1p-dependent promoters; binds calmodulin; stimulates antisense transcription to activate CDC28; defines novel S-phase checkpoint with Mrc1p that prevent replication/transcription conflicts; nuclear form represses pseudohyphal growth; autophosphorylates; protein abundance increases under DNA replication stress [Source:SGD;Acc:S000004103])

HSP 1 Score: 67.0106 bits (162), Expect = 7.858e-12
Identity = 59/219 (26.94%), Postives = 104/219 (47.49%), Query Frame = 3
Query:   75 VKDRWKVIRKLGGGGFGEIYECLDSHTQEKVALK-----LESSRIAKQVLKMEVAVLKKLQGTAHVCK---FLGCGRNDRFNYVAMTLQGKNLADLRRAQKNSAFSISTMLRLSAQILQSIQDIHNSGFLHRDIKPSNFSMGRLPLSSHTVVMLDFGLARQYILPDGNGDIRAPRPVTGFRGTVRYASVNAHMNREMGRHD---DLWSAFYMMAEMVTG 698
            + +R+  +  +G G FG +    D+ T + VA+K       ++ +AK+  + E+ +LK L+    +C    FL    +    Y    LQG    DL R  +        +     QIL+ ++ +H++G +HRD+KPSN  +      +  + + DFGLAR          I+ P+ +TG+  T  Y +    +  +  ++D   D+WSA  + AEM+ G
Sbjct:   19 ITNRYNDLNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTAVLAKRTYR-ELKLLKHLRHENLICLQDIFLSPLED---IYFVTELQG---TDLHRLLQTRPLEKQFVQYFLYQILRGLKYVHSAGVIHRDLKPSNILINE----NCDLKICDFGLAR----------IQDPQ-MTGYVSTRYYRAPEIMLTWQ--KYDVEVDIWSAGCIFAEMIEG 213          
BLAST of Protein kinase vs. Ensembl Nematostella
Match: EDO46789 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RP40])

HSP 1 Score: 370.548 bits (950), Expect = 2.607e-119
Identity = 179/307 (58.31%), Postives = 228/307 (74.27%), Query Frame = 3
Query:   48 TDLLNPSNIVKDRWKVIRKLGGGGFGEIYECLDSHTQEKVALKLESSRIAKQVLKMEVAVLKKLQGTAHVCKFLGCGRNDRFNYVAMTLQGKNLADLRRAQKNSAFSISTMLRLSAQILQSIQDIHNSGFLHRDIKPSNFSMGRLPLSSHTVVMLDFGLARQYILPDGNGDIRAPRPVTGFRGTVRYASVNAHMNREMGRHDDLWSAFYMMAEMVTGSLPWRKLKDKDQVGQIKQNFEHTQLLRHLPSEFKLLLSHIQSLTYFDAPDYEYLKNLIYQCMRRKGISSDELFDWETT-SDIRQSVQSSS 965
             DLL P ++V+ RWK+I+K+GGGGFGEIY  LD  T++ VA+KLES   +KQVLKMEVAVLKKLQG  H+CKF+ CGRN+ FNY+ M+LQG NLA+LRR+Q    FS STMLRL  QIL+S++ IH +GFLHRDIKPSNF+MG  P + H   MLDFGL+RQ+     NG++R PR   GFRGTVRYAS+NAH N+EMGRHDDLWS FY+M E   G LPWRK+KDK+QVG++K+ ++   LL+ +P EFK  + HI  L Y D PDY+ L  L+ Q ++RKGI   + +DWETT  D  Q+  ++S
Sbjct:    2 ADLLKPGDVVRQRWKIIKKIGGGGFGEIYRGLDQVTKDYVAIKLESVHQSKQVLKMEVAVLKKLQGVDHICKFISCGRNESFNYLVMSLQGSNLAELRRSQPKGVFSHSTMLRLGTQILKSVKSIHEAGFLHRDIKPSNFAMGNTPDTVHICYMLDFGLSRQFT--KANGEVRPPRNTAGFRGTVRYASINAHENKEMGRHDDLWSFFYLMVEFTVGQLPWRKMKDKEQVGKMKKTYDIANLLKSMPGEFKQFVDHISKLKYEDKPDYKMLLGLLEQIIKRKGIKESDPYDWETTPCDCSQTTHTTS 306          
BLAST of Protein kinase vs. Ensembl Nematostella
Match: EDO34742 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SNG2])

HSP 1 Score: 177.948 bits (450), Expect = 1.378e-48
Identity = 106/289 (36.68%), Postives = 154/289 (53.29%), Query Frame = 3
Query:   75 VKDRWKVIRKLGGGGFGEIYECLDSHTQEKVALKLESSRIAKQVLKMEVAVLKKLQGTAHVCKFLGCGRNDRFNYVAMTLQGKNLADLRRAQKNSAFSISTMLRLSAQILQSIQDIHNSGFLHRDIKPSNFSMGRLPLSSHTVVMLDFGLARQYILPDGNGDIRAPRPVTGFRGTVRYASVNAHMNREMGRHDDLWSAFYMMAEMVTGSLPWRKLKDK------DQVGQIKQNFEHTQLLRHLPSEFKLLLSHIQSLTYFDAPDYEYLKNLIYQCMRRKGISSDELFDW 923
            V +++++ RK+G G FG+IY      T E+VA+KLE  +     L +E    K +QG   +     CG    +N + M L G +L DL     N  FSI T+L L+ Q +  I+ +H+  F+HRDIKP NF MG L    + V ++DFGLA++Y  P  +  I   R      GT RYAS+N H+  E  R DDL S  Y++     GSLPW+ LK        +++ + K +     L +  PSEF   L++ +SL + D PDY YL+ L      R+G + D +FDW
Sbjct:    5 VGNKYRLGRKIGSGSFGDIYLGTSISTGEEVAIKLECVKTKHPQLHIEAKFYKMMQGGVGIPTIKWCGTEGDYNVLVMELLGPSLEDLFNFC-NRKFSIKTVLLLADQTISRIEYVHSKNFIHRDIKPDNFLMG-LGKKGNLVYIIDFGLAKKYRDPRTHQHI-PYRENKNLTGTARYASINTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKKMSTPIEVLCKGFPSEFATYLNNCRSLRFDDKPDYSYLRQLFRNLFHRQGYTYDYVFDW 290          
BLAST of Protein kinase vs. Ensembl Nematostella
Match: EDO48738 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RIM1])

HSP 1 Score: 167.933 bits (424), Expect = 8.148e-46
Identity = 106/325 (32.62%), Postives = 172/325 (52.92%), Query Frame = 3
Query:   72 IVKDRWKVIRKLGGGGFGEIYECLDSHTQEKVALKLESSRIAKQVLKMEVAVLKKLQGTAHVCKFLGCGRNDRFNYVAMTLQGKNLADLRRAQKNSAFSISTMLRLSAQILQSIQDIHNSGFLHRDIKPSNFSMGRLPLSSHTVVMLDFGLARQYILPDGNGDIRAPRPVTGFRGTVRYASVNAHMNREMGRHDDLWSAFYMMAEMVTGSLPWRKLKDK------DQVGQIKQNFEHTQLLRHLPSEFKLLLSHIQSLTYFDAPDYEYLKNLIYQCMRRKGISSDELFDWETT---SDIRQSVQSSSV-TGGRNPHHNFRKKPTS 1016
            IV+ +++++RK+G G FG+IY C+ +   E+ A+KLES +     L  E  + K L G + +       + + +N + M L G +L DL     N  F++ T+L L+ Q++  I+ +HN  F+HRDIKP NF MG +    + + ++DFGLA++Y        I + R      GT RYAS+NAH+  E  R DD+ S  Y++      +LPW+ LK        +++ + K +     L +  P+EF + L++ + L + +APDY YL+ L     R      D +FDW T    S  + +V  ++V T G  PH    ++ TS
Sbjct:    9 IVQGKYRLVRKIGSGSFGDIYLCVHTENGEEKAVKLESQKARHPQLLYESKLYKILAGGSGIPAIRHFSQENDYNVLVMDLLGPSLEDLFNFC-NRKFNMKTVLMLADQMIARIEYVHNKNFIHRDIKPDNFLMG-IGRHCNKLYLIDFGLAKKYRDSRTKQHI-SYREDKNLTGTARYASINAHLGIEQSRRDDMESLGYVLMYFNRSNLPWQGLKAATKKQKYEKISEKKMSTPVEVLCKGFPAEFSMYLNYCKGLRFEEAPDYMYLRQLFRILFRTLNHQYDYIFDWTTLKQKSGCQGAVPGTAVATPGTAPHTAQYRRETS 330          
BLAST of Protein kinase vs. Ensembl Nematostella
Match: EDO46523 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RPJ6])

HSP 1 Score: 163.696 bits (413), Expect = 2.811e-44
Identity = 106/322 (32.92%), Postives = 165/322 (51.24%), Query Frame = 3
Query:   75 VKDRWKVIRKLGGGGFGEIYECLDSHTQEKVALKLESSRIAKQVLKMEVAVLKKLQGTAHVCKFLGCGRNDRFNYVAMTLQGKNLADL-----RRAQKNSAFSISTMLRLSAQILQSIQDIHNSGFLHRDIKPSNFSMGRLPLSSHTVVMLDFGLARQYILPDGNGDIRAP-RPVTGFRGTVRYASVNAHMNREMGRHDDLWSAFYMMAEMVTGSLPWRKLKDK------DQVGQIKQNFEHTQLLRHLPSEFKLLLSHIQSLTYFDAPDYEYLKNLIYQCMRRKGISSDELFDWETTSD-IRQSVQSSSVT---GGRNPHH 992
            V  +++++RK+G G FG+IY  +++   E+VA+KLES +     L  E  + K LQG   +      G+   +N + M L G +L DL     RR      F++ T+L L+ Q++  I+ +HN  F+HRDIKP NF MG +    + + ++DFGLA++Y   D       P R      GT RYAS+NAH+  E  R DD+ S  Y++      SLPW+ LK        +++ + K +     L +  P+EF + L++ + L + +APDY YL+ L     R      D +FDW        Q+  +S+V    G   P H
Sbjct:   15 VGGKYRLVRKIGSGSFGDIYLAINTTNGEEVAVKLESQKARHPQLLYESKLYKILQGGVGIPSVRYYGQERDYNVLVMELLGPSLEDLFNFCSRR------FTMKTVLMLADQMISRIEYVHNKNFIHRDIKPDNFLMG-VGKHCNKLFLIDFGLAKKY--RDSRTRQHIPYREDKNLTGTARYASINAHLGIEQSRRDDMESLGYVLMYFNRTSLPWQGLKAATKKQKYEKISEKKMSTPVEVLCKGFPAEFAMYLNYCRGLRFEEAPDYMYLRQLFRILFRTLNYQYDYIFDWTMLKQKAAQATATSTVAPSPGAGTPVH 327          
BLAST of Protein kinase vs. Ensembl Nematostella
Match: EDO34289 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SPP6])

HSP 1 Score: 165.236 bits (417), Expect = 1.334e-43
Identity = 101/294 (34.35%), Postives = 152/294 (51.70%), Query Frame = 3
Query:   72 IVKDRWKVIRKLGGGGFGEIYECLDSHTQEKVALKLESSRIAKQVLKMEVAVLKKL---QGTAHVCKFLGCGRNDRFNYVAMTLQGKNLADLRRAQKNSAFSISTMLRLSAQILQSIQDIHNSGFLHRDIKPSNFSMGRLPLSSH-TVVMLDFGLARQYILPDGNGDIRAPRPVTGFRGTVRYASVNAHMNREMGRHDDLWSAFYMMAEMVTGSLPWRKLKDK------DQVGQIKQNFEHTQLLRHLPSEFKLLLSHIQSLTYFDAPDYEYLKNLIYQCMRRKGISSDELFDW 923
            +V   ++V +K+G G FGE+    + +  E VA+KLE  +     L +E    K L   +G   V  F  CG+   +N + M L G +L DL     N  FS+ T+L ++ Q++  I+ +H+   ++RDIKP NF +GR       T+ ++DFGLA++YI P+    I   R      GT RY S+N H+ +E  R DDL +  +M    + GSLPW+ LK         ++G  K+      L  + P E    L +++ L +F+ PDYEYL+ L    M RKG   D  FDW
Sbjct:   41 MVGPNFRVGKKIGCGNFGELRLGKNLYNNEHVAIKLEPMKSRAPQLHLEYRFYKALGNAEGIPQVHYFGPCGK---YNALVMELLGPSLEDLFDLC-NRQFSLKTVLMVALQLISRIEYVHSKNMIYRDIKPENFLIGRKSAGKEKTINIIDFGLAKEYIDPETKKHIPY-REHKSLTGTARYMSINTHLGKEQSRRDDLEALGHMFMYFLRGSLPWQGLKADTLKERYQKIGDTKRATPIEVLCENHPEEMATYLRYVRRLDFFETPDYEYLRKLFRDLMERKGYVEDFEFDW 329          
BLAST of Protein kinase vs. Ensembl Medaka
Match: ttbk2a (tau tubulin kinase 2 [Source:NCBI gene;Acc:101174145])

HSP 1 Score: 395.971 bits (1016), Expect = 1.436e-118
Identity = 190/343 (55.39%), Postives = 245/343 (71.43%), Query Frame = 3
Query:   42 QETDLLNPSNIVKDRWKVIRKLGGGGFGEIYECLDSHTQEKVALKLESSRIAKQVLKMEVAVLKKLQGTAHVCKFLGCGRNDRFNYVAMTLQ-GKNLADLRRAQKNSAFSISTMLRLSAQILQSIQDIHNSGFLHRDIKP-SNFSMGRLPLSSHTVVMLDFGLARQYILPDGNGDIRAPRPVTGFRGTVRYASVNAHMNREMGRHDDLWSAFYMMAEMVTGSLPWRKLKDKDQVGQIKQNFEHTQLLRHLPSEFKLLLSHIQSLTYFDAPDYEYLKNLIYQCMRRKGISSDELFDWETTSDIRQSVQSSSVTGGRNPHHNFRKKPTSNI--GSLKDGDKSNKN 1058
            +  D+L+  ++VK+RWKV+RK+GGGGFGEIYE +D  T+  VALK+ES++  KQVLKMEVAVLKKLQ   H+C+F+GCGRNDRFNYV M LQ G+NLADLRR+     FSIST LRL  QIL++I+ IH+ GFLHRDIKP SNF+MGR P +  T  MLDFGLARQ+   +   ++R PRPV GFRGTVRYASVNAH N+EMGRHDDLWS FYM+ E + G LPWRK+K+K+QVG++K+ ++H  +LRHLP+EF + L HI +L YF  PDY+ L ++    M+   +  ++ +DWE TS       S+S T    P H+ R  P   +   SL  GD   +N
Sbjct:    6 EPADILSVLSLVKERWKVVRKIGGGGFGEIYEAMDLLTRASVALKVESAQQPKQVLKMEVAVLKKLQ-KDHICRFVGCGRNDRFNYVVMELQQGRNLADLRRSMPRGTFSISTTLRLGHQILEAIESIHSVGFLHRDIKPQSNFAMGRFPSTCRTCYMLDFGLARQFT--NSCQEVRPPRPVAGFRGTVRYASVNAHKNKEMGRHDDLWSLFYMLVEFLVGQLPWRKIKEKEQVGKLKETYDHCLMLRHLPAEFGVFLDHISNLDYFTKPDYQLLMSVFDNSMKTYNVVENDPYDWERTSTDGTVTISASTT---TPQHHTRLTPAHMMANASLIPGDLMREN 342          
BLAST of Protein kinase vs. Ensembl Medaka
Match: ttbk1a (tau tubulin kinase 1 [Source:NCBI gene;Acc:105354132])

HSP 1 Score: 377.867 bits (969), Expect = 5.310e-116
Identity = 184/321 (57.32%), Postives = 232/321 (72.27%), Query Frame = 3
Query:   27 MPSTKQETDLLNPSNIVKDRWKVIRKLGGGGFGEIYECLDSHTQEKVALKLESSRIAKQVLKMEVAVLKKLQGTA-------HVCKFLGCGRNDRFNYVAMTLQGKNLADLRRAQKNSAFSISTMLRLSAQILQSIQDIHNSGFLHRDIKPSNFSMGRLPLSSHTVVMLDFGLARQYILPDGNGDIRAPRPVTGFRGTVRYASVNAHMNREMGRHDDLWSAFYMMAEMVTGSLPWRKLKDKDQVGQIKQNFEHTQLLRHLPSEFKLLLSHIQSLTYFDAPDYEYLKNLIYQCMRRKGISSDELFDWET-TSDIRQSVQSSS 965
            M  T ++ D+L P+ +VKDRWKV++K+GGGGFGEIYE LD  T+E VALK+ES++  KQVLKMEVAVLKKLQG          V  FLG   N  F +V +  QG+NLADLRR+Q    F++ST LRL  QIL+SI+ IH+ GFLHRDIKPSNF+MGRLP +     MLDFGLARQY   + NG++R PR V GFRGTVRYASVNAH N+EMGRHDDLWS FYM+ E   G LPWRK+KDK+QVGQIK+ F+H  LL+H+PSEF + L H+ +L Y+  PDY+ L ++    M+ + I+ +E FDWE   SD+  S  +S+
Sbjct:   14 MNGTSEQADILPPNCMVKDRWKVLKKIGGGGFGEIYEALDLLTRENVALKVESAQQPKQVLKMEVAVLKKLQGETLLHEHEDPVVSFLG---NKLFFFVWLA-QGRNLADLRRSQPRGTFTMSTTLRLGKQILESIEAIHSVGFLHRDIKPSNFAMGRLPSTYRKCYMLDFGLARQYT--NTNGEVRPPRTVAGFRGTVRYASVNAHKNKEMGRHDDLWSLFYMLVEFAVGQLPWRKIKDKEQVGQIKERFDHKMLLKHMPSEFSIFLDHVLALDYYTKPDYQLLMSVFENSMKERIITENEPFDWEKGGSDVTLSTSAST 328          
BLAST of Protein kinase vs. Ensembl Medaka
Match: ttbk2a (tau tubulin kinase 2 [Source:NCBI gene;Acc:101174145])

HSP 1 Score: 354.369 bits (908), Expect = 7.157e-111
Identity = 175/348 (50.29%), Postives = 226/348 (64.94%), Query Frame = 3
Query:   27 MPSTKQETDLLNPSNIVKDRWKVIRKLGGGGFGEIYECLDSHTQEKVALKLESSRIAKQVLKMEVAVLKKLQGTAHVCKFLGCGRNDRFNYVAMTLQGKNLADLRRAQKNSAFSISTMLRLSAQILQSIQDIHNSGFLHRDIKPSNFSMGRLPLSSHTVVMLDFGLARQYILPDGNGDIRAPRPVTGFRGTVRYASVNAHMNREMGRHDDLWSAFYMMAEMVTGSLPWRKLKDKDQVGQIKQNFEHTQLLRHLPSEFKLLLSHIQSLTYFDAPDYEYLKNLIYQCMRRKGISSDELFDWETTSDIRQSVQSSSVTGGRNPHHNFRKKPTSNIG----SLKDGDKSNKN 1058
            M    +  D+L+  ++VK+RWKV+RK+GGGGFGEIYE +D  T+  VALK+ES++  KQVLKMEVAVLKKLQG  H+C+F+GCGRNDRFNYV M LQG+NLADLRR+     FSIST LRL  QIL++I+ IH+ GFLHRDIKP                                     PRPV GFRGTVRYASVNAH N+EMGRHDDLWS FYM+ E + G LPWRK+K+K+QVG++K+ ++H  +LRHLP+EF + L HI +L YF  PDY+ L ++    M+   +  ++ +DWE TS       S+S T    P H+ R  P +++G    SL  GD   +N
Sbjct:    1 MSGGVEPADILSVLSLVKERWKVVRKIGGGGFGEIYEAMDLLTRASVALKVESAQQPKQVLKMEVAVLKKLQGKDHICRFVGCGRNDRFNYVVMELQGRNLADLRRSMPRGTFSISTTLRLGHQILEAIESIHSVGFLHRDIKP-------------------------------------PRPVAGFRGTVRYASVNAHKNKEMGRHDDLWSLFYMLVEFLVGQLPWRKIKEKEQVGKLKETYDHCLMLRHLPAEFGVFLDHISNLDYFTKPDYQLLMSVFDNSMKTYNVVENDPYDWERTSTDGTVTISASTT---TPQHHTRLTP-AHMGMANASLIPGDLMREN 307          
BLAST of Protein kinase vs. Ensembl Medaka
Match: ttbk2b (tau-tubulin kinase 2 [Source:NCBI gene;Acc:101157747])

HSP 1 Score: 351.673 bits (901), Expect = 5.371e-110
Identity = 162/293 (55.29%), Postives = 200/293 (68.26%), Query Frame = 3
Query:   48 TDLLNPSNIVKDRWKVIRKLGGGGFGEIYECLDSHTQEKVALKLESSRIAKQVLKMEVAVLKKLQGTAHVCKFLGCGRNDRFNYVAMTLQGKNLADLRRAQKNSAFSISTMLRLSAQILQSIQDIHNSGFLHRDIKPSNFSMGRLPLSSHTVVMLDFGLARQYILPDGNGDIRAPRPVTGFRGTVRYASVNAHMNREMGRHDDLWSAFYMMAEMVTGSLPWRKLKDKDQVGQIKQNFEHTQLLRHLPSEFKLLLSHIQSLTYFDAPDYEYLKNLIYQCMRRKGISSDELFDWE 926
            TD+L   ++V+DRWKVIRK+GGGGFGEIYE LD  +Q  VALK+ES++  KQVLKMEVAVLKKLQG  HVC+F+GCGRNDRFNYV M LQG+NLADLRR      FS+ST LRL  QIL++I+ IH+ GFLHRDIKP                                     PRPV GFRGTVRYAS+NAH N+EMGRHDDLWS FYM+ E + G LPWRK+KDK+QVG +K+ ++H  +L+HLPSEF   L HI +L YF  PDY+ L ++    M+   +  ++ +DWE
Sbjct:    8 TDILTVGDVVRDRWKVIRKIGGGGFGEIYEVLDQLSQATVALKVESAQQPKQVLKMEVAVLKKLQGKNHVCRFVGCGRNDRFNYVVMELQGRNLADLRRTMSRGTFSVSTTLRLGKQILEAIESIHSVGFLHRDIKP-------------------------------------PRPVAGFRGTVRYASINAHKNKEMGRHDDLWSLFYMLVEFMVGQLPWRKIKDKEQVGNLKETYDHRLMLKHLPSEFSTFLDHIMTLDYFTKPDYQLLTSMFDSAMKSHNVLENDPYDWE 263          
BLAST of Protein kinase vs. Ensembl Medaka
Match: csnk1db (casein kinase 1 delta [Source:NCBI gene;Acc:101156740])

HSP 1 Score: 176.407 bits (446), Expect = 1.721e-47
Identity = 106/290 (36.55%), Postives = 154/290 (53.10%), Query Frame = 3
Query:   75 VKDRWKVIRKLGGGGFGEIYECLDSHTQEKVALKLESSRIAKQVLKMEVAVLKKLQGTAHVCKFLGCGRNDRFNYVAMTLQGKNLADLRRAQKNSAFSISTMLRLSAQILQSIQDIHNSGFLHRDIKPSNFSMGRLPLSSHTVVMLDFGLARQYILPDGNGDIRAP-RPVTGFRGTVRYASVNAHMNREMGRHDDLWSAFYMMAEMVTGSLPWRKLKDK------DQVGQIKQNFEHTQLLRHLPSEFKLLLSHIQSLTYFDAPDYEYLKNLIYQCMRRKGISSDELFDW 923
            V +R+++ RK+G G FG+IY   D    E+VA+KLE  +     L +E  + K +QG   +     CG    +N + M L G +L DL     +  FS+ T+L L+ Q++  I+ IH+  F+HRD+KP NF MG L    + V ++DFGLA++Y   D       P R      GT RYAS+N H+  E  R DDL S  Y++     GSLPW+ LK        +++ + K +     L +  PSEF   L+  +SL + D PDY YL+ L      R+G S D +FDW
Sbjct:    5 VGNRYRLGRKIGSGSFGDIYLGTDISVGEEVAIKLECVKTKHPQLHIESKIYKMMQGGVGIPIIKWCGAEGDYNVMVMELLGPSLEDLFNFC-SRKFSLKTVLLLADQMISRIEYIHSKNFIHRDVKPDNFLMG-LGKKGNLVYIIDFGLAKKY--RDARTHQHIPYRENKNLTGTARYASINTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKKMSTPIEVLCKGYPSEFATYLNFCRSLRFDDKPDYSYLRQLFRNLFHRQGFSYDYVFDW 290          
BLAST of Protein kinase vs. Planmine SMEST
Match: SMESG000030545.1 (SMESG000030545.1)

HSP 1 Score: 2202.94 bits (5707), Expect = 0.000e+0
Identity = 1136/1139 (99.74%), Postives = 1137/1139 (99.82%), Query Frame = 3
Query:   27 MPSTKQETDLLNPSNIVKDRWKVIRKLGGGGFGEIYECLDSHTQEKVALKLESSRIAKQVLKMEVAVLKKLQGTAHVCKFLGCGRNDRFNYVAMTLQGKNLADLRRAQKNSAFSISTMLRLSAQILQSIQDIHNSGFLHRDIKPSNFSMGRLPLSSHTVVMLDFGLARQYILPDGNGDIRAPRPVTGFRGTVRYASVNAHMNREMGRHDDLWSAFYMMAEMVTGSLPWRKLKDKDQVGQIKQNFEHTQLLRHLPSEFKLLLSHIQSLTYFDAPDYEYLKNLIYQCMRRKGISSDELFDWETTSDIRQSVQSSSVTGGRNPHHNFRKKPTSNIGSLKDGDKSNKNQSINIHQKSKVITNHKHKPLKSNDETGLESGPRPPPRIMKSTKQEESSKMNGKQIISFQEVVGADDENYVEVYNIPNRNGKQTKQCLVEESLKNVQMENYRKESTTEYKKLHRNISIKKLERQDSLNSKYHSKLPILLKSQSRDSSPNYLESNAQTKQLKSSNMNSSGQMYKVARISSITDSAFVDIDNKPAVANIETQRHSKQSLNITNIDQEDYNAVEEIQEASKSLSCSSDDYEKEFSHRYKNRKEIDKDSSHQKISARIEVNTTSPIELKPLQLDQNTKANLNDPIXXXXXXXXXMCKSKMDSLSRRISVAFSVGSRATRAINEDKFDYSNAYDATKMLHLTHYSDNYGYDDKDISENFRDVFIADNSLQXXXXXXXXXXMMLHNEKLLSNQSRSKDGXXXXXXXXXXXXFTNNKFEKQSLFINPXXXXXXXXXXXXXXXXXXXXXLKKSFSRQVSEELPQPSQFIDNHAKLNAENDFYVTCVNSPSACAFPSSNRIPPKCNDRKPYRQRCGSSPVPNVLRCSFNDPACNGYPDKANESAPTEPNTNQNRILITSHCEKDFQKAVNRANACERYLENISDPNKSRIPINSTVKPTKESSILLNTNRNKFPNQKSFSRPNRTITKTPASFIDRQSRTDSMKSNFQENNQRRRSASRDSIVMQKHHPCSNVNTLYYSQKLSNCRLTNSNTDIHKHSXXXXXXXXXXXXXXSMRNNHNSQQQSAGNQESLLSKPIRPRSQSLKNSIICRSYNDIFESVITIPALMPTERLKSHNQFQQNLISCESIVDKEIKVK 3443
            MPSTKQETDLLNPSNIVKDRWKVIRKLGGGGFGEIYECLDSHTQEKVALKLESSRIAKQVLKMEVAVLKKLQGTAHVCKFLGCGRNDRFNYVAMTLQGKNLADLRRAQKNSAFSISTMLRLSAQILQSIQDIHNSGFLHRDIKPSNFSMGRLPLSSHTVVMLDFGLARQYILPDGNGDIRAPRPVTGFRGTVRYASVNAHMNREMGRHDDLWSAFYMMAEMVTGSLPWRKLKDKDQVGQIKQNFEHTQLLRHLPSEFKLLLSHIQSLTYFDAPDYEYLKNLIYQCMRRKGISSDELFDWETT DIRQS+QSSSVTGGRNPHHNFRKKPTSNIGSLKDGDKSNKNQSINIHQKSKVITNHKHKPLKSNDETGLESGPRPPPRIMKSTKQEESSKMNGKQIISFQEVVGADDENYVEVYNIPNRNGKQTKQCLVEESLKNVQMENYRKESTTEYKKLHRNISIKKLERQDSLNSKYHSKLPILLKSQSRDSSPNYLESNAQTKQLKSSNMNSSGQMYKVARISSITDSAFVDIDNKPAVANIETQRHSKQSLNITNIDQEDYNAVEEIQEASKSLSCSSDDYEKEFSHRYKNRKEIDKDSSHQKISARIEVNTTSPIELKPLQLDQNTKANLNDPIHHHNHHHHHMCKSKMDSLSRRISVAFSVGSRATRAINEDKFDYSNAYDATKMLHLTHYSDNYGYDDKDISENFRDVFIADNSLQKSSSKHSSHKMMLHNEKLLSNQSRSKDGSLESLKSKSIKSFTNNKFEKQSLFINPSKSISCKSSKISASDYSKYASLKKSFSRQVSEELPQPSQFIDNHAKLNAENDFYVTCVNSPSACAFPSSNRIPPKCNDRKPYRQRCGSSPVPNVLRCSFNDPACNGYPDKANESAPTEPNTNQNRILITSHCEKDFQKAVNRANACERYLENISDPNKSRIPINSTVKPTKESSILLNTNRNKFPNQKSFSRPNRTITKTPASFIDRQSRTDS KSNFQENNQRRRSASRDSIVMQKHHPCSNVNTLYYSQKLSNCRLTNSNTDIHKHSTGGTNATAAGCGACSMRNNHNSQQQSAGNQESLLSKPIRPRSQSLKNSIICRSYNDIFESVITIPALMPTERLKSHNQFQQNLISCESIVDKEIKVK
Sbjct:    1 MPSTKQETDLLNPSNIVKDRWKVIRKLGGGGFGEIYECLDSHTQEKVALKLESSRIAKQVLKMEVAVLKKLQGTAHVCKFLGCGRNDRFNYVAMTLQGKNLADLRRAQKNSAFSISTMLRLSAQILQSIQDIHNSGFLHRDIKPSNFSMGRLPLSSHTVVMLDFGLARQYILPDGNGDIRAPRPVTGFRGTVRYASVNAHMNREMGRHDDLWSAFYMMAEMVTGSLPWRKLKDKDQVGQIKQNFEHTQLLRHLPSEFKLLLSHIQSLTYFDAPDYEYLKNLIYQCMRRKGISSDELFDWETTGDIRQSIQSSSVTGGRNPHHNFRKKPTSNIGSLKDGDKSNKNQSINIHQKSKVITNHKHKPLKSNDETGLESGPRPPPRIMKSTKQEESSKMNGKQIISFQEVVGADDENYVEVYNIPNRNGKQTKQCLVEESLKNVQMENYRKESTTEYKKLHRNISIKKLERQDSLNSKYHSKLPILLKSQSRDSSPNYLESNAQTKQLKSSNMNSSGQMYKVARISSITDSAFVDIDNKPAVANIETQRHSKQSLNITNIDQEDYNAVEEIQEASKSLSCSSDDYEKEFSHRYKNRKEIDKDSSHQKISARIEVNTTSPIELKPLQLDQNTKANLNDPIHHHNHHHHHMCKSKMDSLSRRISVAFSVGSRATRAINEDKFDYSNAYDATKMLHLTHYSDNYGYDDKDISENFRDVFIADNSLQKSSSKHSSHKMMLHNEKLLSNQSRSKDGSLESLKSKSIKSFTNNKFEKQSLFINPSKSISCKSSKISASDYSKYASLKKSFSRQVSEELPQPSQFIDNHAKLNAENDFYVTCVNSPSACAFPSSNRIPPKCNDRKPYRQRCGSSPVPNVLRCSFNDPACNGYPDKANESAPTEPNTNQNRILITSHCEKDFQKAVNRANACERYLENISDPNKSRIPINSTVKPTKESSILLNTNRNKFPNQKSFSRPNRTITKTPASFIDRQSRTDSTKSNFQENNQRRRSASRDSIVMQKHHPCSNVNTLYYSQKLSNCRLTNSNTDIHKHSTGGTNATAAGCGACSMRNNHNSQQQSAGNQESLLSKPIRPRSQSLKNSIICRSYNDIFESVITIPALMPTERLKSHNQFQQNLISCESIVDKEIKVK 1139          
BLAST of Protein kinase vs. Planmine SMEST
Match: SMESG000030545.1 (SMESG000030545.1)

HSP 1 Score: 2196.39 bits (5690), Expect = 0.000e+0
Identity = 1134/1138 (99.65%), Postives = 1136/1138 (99.82%), Query Frame = 3
Query:   27 MPSTKQETDLLNPSNIVKDRWKVIRKLGGGGFGEIYECLDSHTQEKVALKLESSRIAKQVLKMEVAVLKKLQGTAHVCKFLGCGRNDRFNYVAMTLQGKNLADLRRAQKNSAFSISTMLRLSAQILQSIQDIHNSGFLHRDIKPSNFSMGRLPLSSHTVVMLDFGLARQYILPDGNGDIRAPRPVTGFRGTVRYASVNAHMNREMGRHDDLWSAFYMMAEMVTGSLPWRKLKDKDQVGQIKQNFEHTQLLRHLPSEFKLLLSHIQSLTYFDAPDYEYLKNLIYQCMRRKGISSDELFDWETTSDIRQSVQSSSVTGGRNPHHNFRKKPTSNIGSLKDGDKSNKNQSINIHQKSKVITNHKHKPLKSNDETGLESGPRPPPRIMKSTKQEESSKMNGKQIISFQEVVGADDENYVEVYNIPNRNGKQTKQCLVEESLKNVQMENYRKESTTEYKKLHRNISIKKLERQDSLNSKYHSKLPILLKSQSRDSSPNYLESNAQTKQLKSSNMNSSGQMYKVARISSITDSAFVDIDNKPAVANIETQRHSKQSLNITNIDQEDYNAVEEIQEASKSLSCSSDDYEKEFSHRYKNRKEIDKDSSHQKISARIEVNTTSPIELKPLQLDQNTKANLNDPIXXXXXXXXXMCKSKMDSLSRRISVAFSVGSRATRAINEDKFDYSNAYDATKMLHLTHYSDNYGYDDKDISENFRDVFIADNSLQXXXXXXXXXXMMLHNEKLLSNQSRSKDGXXXXXXXXXXXXFTNNKFEKQSLFINPXXXXXXXXXXXXXXXXXXXXXLKKSFSRQVSEELPQPSQFIDNHAKLNAENDFYVTCVNSPSACAFPSSNRIPPKCNDRKPYRQRCGSSPVPNVLRCSFNDPACNGYPDKANESAPTEPNTNQNRILITSHCEKDFQKAVNRANACERYLENISDPNKSRIPINSTVKPTKESSILLNTNRNKFPNQKSFSRPNRTITKTPASFIDRQSRTDSMKSNFQENNQRRRSASRDSIVMQKHHPCSNVNTLYYSQKLSNCRLTNSNTDIHKHSXXXXXXXXXXXXXXSMRNNHNSQQQSAGNQESLLSKPIRPRSQSLKNSIICRSYNDIFESVITIPALMPTERLKSHNQFQQNLISCESIVDKEIKV 3440
            MPSTKQETDLLNPSNIVKDRWKVIRKLGGGGFGEIYECLDSHTQEKVALKLESSRIAKQVLKMEVAVLKKLQGTAHVCKFLGCGRNDRFNYVAMTLQGKNLADLRRAQKNSAFSISTMLRLSAQILQSIQDIHNSGFLHRDIKPSNFSMGRLPLSSHTVVMLDFGLARQYILPDGNGDIRAPRPVTGFRGTVRYASVNAHMNREMGRHDDLWSAFYMMAEMVTGSLPWRKLKDKDQVGQIKQNFEHTQLLRHLPSEFKLLLSHIQSLTYFDAPDYEYLKNLIYQCMRRKGISSDELFDWETT DIRQS+QSSSVTGGRNPHHNFRKKPTSNIGSLKDGDKSNKNQSINIHQKSKVITNHKHKPLKSNDETGLESGPRPPPRIMKSTKQEESSKMNGKQIISFQEVVGADDENYVEVYNIPNRNGKQTKQCLVEESLKNVQMENYRKESTTEYKKLHRNISIKKLERQDSLNSKYHSKLPILLKSQSRDSSPNYLESNAQTKQLKSSNMNSSGQMYKVARISSITDSAFVDIDNKPAVANIETQRHSKQSLNITNIDQEDYNAVEEIQEASKSLSCSSDDYEKEFSHRYKNRKEIDKDSSHQKISARIEVNTTSPIELKPLQLDQNTKANLNDPIHHHNHHHHHMCKSKMDSLSRRISVAFSVGSRATRAINEDKFDYSNAYDATKMLHLTHYSDNYGYDDKDISENFRDVFIADNSLQKSSSKHSSHKMMLHNEKLLSNQSRSKDGSLESLKSKSIKSFTNNKFEKQSLFINPSKSISCKSSKISASDYSKYASLKKSFSRQVSEELPQPSQFIDNHAKLNAENDFYVTCVNSPSACAFPSSNRIPPKCNDRKPYRQRCGSSPVPNVLRCSFNDPACNGYPDKANESAPTEPNTNQNRILITSHCEKDFQKAVNRANACERYLENISDPNKSRIPINSTVKPTKESSILLNTNRNKFPNQKSFSRPNRTITKTPASFIDRQSRTDS KSNFQENNQRRRSASRDSIVMQKHHPCSNVNTLYYSQKLSNCRLTNSNTDIHKHSTGGTNATAAGCGACSMRNNHNSQQQSAGNQESLLSKPIRPRSQSLKNSIICRSYNDIFESVITIPALMPTERLKSHNQFQQNLISCESIVDKEIK+
Sbjct:    1 MPSTKQETDLLNPSNIVKDRWKVIRKLGGGGFGEIYECLDSHTQEKVALKLESSRIAKQVLKMEVAVLKKLQGTAHVCKFLGCGRNDRFNYVAMTLQGKNLADLRRAQKNSAFSISTMLRLSAQILQSIQDIHNSGFLHRDIKPSNFSMGRLPLSSHTVVMLDFGLARQYILPDGNGDIRAPRPVTGFRGTVRYASVNAHMNREMGRHDDLWSAFYMMAEMVTGSLPWRKLKDKDQVGQIKQNFEHTQLLRHLPSEFKLLLSHIQSLTYFDAPDYEYLKNLIYQCMRRKGISSDELFDWETTGDIRQSIQSSSVTGGRNPHHNFRKKPTSNIGSLKDGDKSNKNQSINIHQKSKVITNHKHKPLKSNDETGLESGPRPPPRIMKSTKQEESSKMNGKQIISFQEVVGADDENYVEVYNIPNRNGKQTKQCLVEESLKNVQMENYRKESTTEYKKLHRNISIKKLERQDSLNSKYHSKLPILLKSQSRDSSPNYLESNAQTKQLKSSNMNSSGQMYKVARISSITDSAFVDIDNKPAVANIETQRHSKQSLNITNIDQEDYNAVEEIQEASKSLSCSSDDYEKEFSHRYKNRKEIDKDSSHQKISARIEVNTTSPIELKPLQLDQNTKANLNDPIHHHNHHHHHMCKSKMDSLSRRISVAFSVGSRATRAINEDKFDYSNAYDATKMLHLTHYSDNYGYDDKDISENFRDVFIADNSLQKSSSKHSSHKMMLHNEKLLSNQSRSKDGSLESLKSKSIKSFTNNKFEKQSLFINPSKSISCKSSKISASDYSKYASLKKSFSRQVSEELPQPSQFIDNHAKLNAENDFYVTCVNSPSACAFPSSNRIPPKCNDRKPYRQRCGSSPVPNVLRCSFNDPACNGYPDKANESAPTEPNTNQNRILITSHCEKDFQKAVNRANACERYLENISDPNKSRIPINSTVKPTKESSILLNTNRNKFPNQKSFSRPNRTITKTPASFIDRQSRTDSTKSNFQENNQRRRSASRDSIVMQKHHPCSNVNTLYYSQKLSNCRLTNSNTDIHKHSTGGTNATAAGCGACSMRNNHNSQQQSAGNQESLLSKPIRPRSQSLKNSIICRSYNDIFESVITIPALMPTERLKSHNQFQQNLISCESIVDKEIKI 1138          
BLAST of Protein kinase vs. Planmine SMEST
Match: SMESG000048011.1 (SMESG000048011.1)

HSP 1 Score: 457.603 bits (1176), Expect = 1.346e-149
Identity = 208/307 (67.75%), Postives = 245/307 (79.80%), Query Frame = 3
Query:   27 MPSTKQETDLLNPSNIVKDRWKVIRKLGGGGFGEIYECLDSHTQEKVALKLESSRIAKQVLKMEVAVLKKLQGTAHVCKFLGCGRNDRFNYVAMTLQGKNLADLRRAQKNSAFSISTMLRLSAQILQSIQDIHNSGFLHRDIKPSNFSMGRLPLSSHTVVMLDFGLARQYILPDGNGDIRAPRPVTGFRGTVRYASVNAHMNREMGRHDDLWSAFYMMAEMVTGSLPWRKLKDKDQVGQIKQNFEHTQLLRHLPSEFKLLLSHIQSLTYFDAPDYEYLKNLIYQCMRRKGISSDELFDWETTSDIRQ 947
            M S    +DLL   N+VKDRW+VIRK+GGGGFGEIYE  D  TQ++VALKLESSR  KQVLKMEVAVLKK+QG  H C+F+GCGRNDRFNY+ M+LQG+NLA+LRR      FS+STML+L  QIL SI+ IH  GFLHRD+KPSNF+MGRLP ++  V +LDFGL+RQY+  D   ++R PRP+ GFRGTVRYAS NAHMNREMGRHDDLWS FYM+ EMVTG LPWRKLKDK+QVGQIKQ+F+HT LLRHLPSEF+L L H+QSLTYFD+PDY  L+NL  +CM RK +   +LFDWET     Q
Sbjct:    1 MGSESDSSDLLQAGNVVKDRWRVIRKIGGGGFGEIYEAFDEATQDRVALKLESSRQPKQVLKMEVAVLKKIQGREHSCRFVGCGRNDRFNYLVMSLQGRNLAELRRNTPRGIFSVSTMLKLGRQILDSIETIHMVGFLHRDVKPSNFAMGRLPQTARIVYILDFGLSRQYLNVD--DEVRTPRPIAGFRGTVRYASTNAHMNREMGRHDDLWSMFYMLVEMVTGQLPWRKLKDKEQVGQIKQSFDHTILLRHLPSEFRLFLEHVQSLTYFDSPDYTMLRNLFDECMLRKRVHESDLFDWETAPSTNQ 305          
BLAST of Protein kinase vs. Planmine SMEST
Match: SMESG000026133.1 (SMESG000026133.1)

HSP 1 Score: 446.432 bits (1147), Expect = 9.935e-136
Identity = 196/303 (64.69%), Postives = 244/303 (80.53%), Query Frame = 3
Query:   27 MPSTKQETDLLNPSNIVKDRWKVIRKLGGGGFGEIYECLDSHTQEKVALKLESSRIAKQVLKMEVAVLKKLQGTAHVCKFLGCGRNDRFNYVAMTLQGKNLADLRRAQKNSAFSISTMLRLSAQILQSIQDIHNSGFLHRDIKPSNFSMGRLPLSSHTVVMLDFGLARQYILPDGNGDIRAPRPVTGFRGTVRYASVNAHMNREMGRHDDLWSAFYMMAEMVTGSLPWRKLKDKDQVGQIKQNFEHTQLLRHLPSEFKLLLSHIQSLTYFDAPDYEYLKNLIYQCMRRKGISSDELFDWETTS 935
            M S+ QE DL +  +++K+RWK+I+KLGGGGFGEIYEC+D   ++KVA+KLESS++ KQVL+MEV+VLKKLQGT H CK  G GRND+F+YVAMTLQGKNLADLRR  K+ +FSIST L+L+ QIL SI++IH+ GFLHRDIKPSNF++G    +   V MLDFGLARQ++LPDG+  +R PR V GFRGTVRYAS+NAH N EMGRHDDLWSAFYM  EM+TG LPWR++KDK+QVGQIK N++HT+ L+ LP+EFK  L+HIQ L YF  PDYE +KNLI  CM+ K ++  + FDWE  S
Sbjct:    1 MTSSTQEPDLASEGDVIKERWKIIKKLGGGGFGEIYECVDPIVKDKVAIKLESSKLPKQVLRMEVSVLKKLQGTKHACKCYGYGRNDKFSYVAMTLQGKNLADLRRQMKSGSFSISTTLQLTLQILDSIENIHSIGFLHRDIKPSNFAIGGSAETRRIVYMLDFGLARQFVLPDGSFQVRPPRDVAGFRGTVRYASMNAHNNVEMGRHDDLWSAFYMFYEMITGQLPWRRMKDKEQVGQIKLNYDHTKFLQSLPNEFKPFLAHIQELDYFKKPDYEMMKNLIRDCMKSKKVTQSDSFDWELNS 303          
BLAST of Protein kinase vs. Planmine SMEST
Match: SMESG000068893.1 (SMESG000068893.1)

HSP 1 Score: 424.476 bits (1090), Expect = 2.219e-132
Identity = 195/301 (64.78%), Postives = 236/301 (78.41%), Query Frame = 3
Query:   27 MPS-TKQETDLLNPSNIVKDRWKVIRKLGGGGFGEIYECLDSHTQEKVALKLESSRIAKQVLKMEVAVLKKLQGTAHVCKFLGCGRNDRFNYVAMTLQGKNLADLRRAQKNSAFSISTMLRLSAQILQSIQDIHNSGFLHRDIKPSNFSMGRLPLSSHTVVMLDFGLARQYILPDGNGDIRAPRPVTGFRGTVRYASVNAHMNREMGRHDDLWSAFYMMAEMVTGSLPWRKLKDKDQVGQIKQNFEHTQLLRHLPSEFKLLLSHIQSLTYFDAPDYEYLKNLIYQCMRRKGISSDELFDWE 926
            MPS T   +DLL P  I+K+RW+V +K+GGGGFG+IYE +D  +QEKVALKLES++ +KQVLKMEVAVLKKLQG  HVC+F GCGRND+FNYV M+LQGKNL +LRRA     FSIS+M+RL+ Q+L+ I+ IH+ GFLHRDIKPSNF+MGRLP +   V MLDFGLARQY+  D  G++R PRPV GFRGTVRYAS NAH N+E+GRHDDLWS  Y+  EMVTG LPWRK+KDK+QVG++KQN +H  LLRH+P EFK +L HIQ L YF  PDY  L+NL+ Q M RK     + FDWE
Sbjct:    1 MPSPTSDSSDLLEPGYIIKERWRVNKKIGGGGFGQIYEAIDLSSQEKVALKLESAQQSKQVLKMEVAVLKKLQGLDHVCRFYGCGRNDKFNYVVMSLQGKNLGELRRATSKGIFSISSMVRLTKQMLECIESIHSVGFLHRDIKPSNFAMGRLPSTFRKVYMLDFGLARQYVNTD--GEVRPPRPVAGFRGTVRYASANAHFNKELGRHDDLWSLLYLAVEMVTGQLPWRKVKDKEQVGKLKQNVDHNLLLRHMPLEFKQILDHIQELHYFAKPDYSKLQNLLDQTMARKLFKFTDPFDWE 299          
The following BLAST results are available for this feature:
BLAST of Protein kinase vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
TTBK26.800e-13061.18tau tubulin kinase 2 [Source:HGNC Symbol;Acc:HGNC:... [more]
TTBK17.451e-12863.73tau tubulin kinase 1 [Source:HGNC Symbol;Acc:HGNC:... [more]
TTBK21.630e-12361.18tau tubulin kinase 2 [Source:HGNC Symbol;Acc:HGNC:... [more]
TTBK11.380e-11364.12tau tubulin kinase 1 [Source:HGNC Symbol;Acc:HGNC:... [more]
TTBK21.218e-10954.93tau tubulin kinase 2 [Source:HGNC Symbol;Acc:HGNC:... [more]
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BLAST of Protein kinase vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ttbk-71.385e-11153.02Tau TuBulin Kinase [Source:UniProtKB/TrEMBL;Acc:Q... [more]
C39H7.18.309e-6739.53pep chromosome:WBcel235:IV:5631895:5633379:1 gene:... [more]
R13H9.51.085e-6641.87pep chromosome:WBcel235:IV:5065746:5066987:-1 gene... [more]
ttbk-22.131e-6641.87Tau TuBulin Kinase [Source:UniProtKB/TrEMBL;Acc:O... [more]
Y38H8A.36.286e-6639.53pep chromosome:WBcel235:IV:13472497:13474005:1 gen... [more]
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BLAST of Protein kinase vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Asator5.780e-13566.78gene:FBgn0039908 transcript:FBtr0300344[more]
Asator5.572e-13266.78gene:FBgn0039908 transcript:FBtr0344869[more]
Asator5.572e-13266.78gene:FBgn0039908 transcript:FBtr0332908[more]
Asator1.413e-13166.78gene:FBgn0039908 transcript:FBtr0332905[more]
Asator1.751e-13166.78gene:FBgn0039908 transcript:FBtr0332904[more]
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BLAST of Protein kinase vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ttbk1a1.474e-12762.67tau tubulin kinase 1a [Source:ZFIN;Acc:ZDB-GENE-10... [more]
ttbk1a1.474e-12762.67tau tubulin kinase 1a [Source:ZFIN;Acc:ZDB-GENE-10... [more]
ttbk1b4.091e-12562.37tau tubulin kinase 1b [Source:ZFIN;Acc:ZDB-GENE-10... [more]
ttbk2a3.189e-12255.69tau tubulin kinase 2a [Source:ZFIN;Acc:ZDB-GENE-12... [more]
ttbk2a1.575e-12155.69tau tubulin kinase 2a [Source:ZFIN;Acc:ZDB-GENE-12... [more]
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BLAST of Protein kinase vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
col24a18.207e-12862.79collagen, type XXIV, alpha 1 [Source:Xenbase;Acc:X... [more]
col24a11.184e-12463.00collagen, type XXIV, alpha 1 [Source:Xenbase;Acc:X... [more]
col24a12.076e-12463.73collagen, type XXIV, alpha 1 [Source:Xenbase;Acc:X... [more]
col24a13.531e-12164.87collagen, type XXIV, alpha 1 [Source:Xenbase;Acc:X... [more]
col24a12.323e-11056.11collagen, type XXIV, alpha 1 [Source:Xenbase;Acc:X... [more]
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BLAST of Protein kinase vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Ttbk11.886e-13163.73tau tubulin kinase 1 [Source:MGI Symbol;Acc:MGI:21... [more]
Ttbk13.202e-12863.73tau tubulin kinase 1 [Source:MGI Symbol;Acc:MGI:21... [more]
Ttbk21.101e-12561.67tau tubulin kinase 2 [Source:MGI Symbol;Acc:MGI:21... [more]
Ttbk25.540e-12361.67tau tubulin kinase 2 [Source:MGI Symbol;Acc:MGI:21... [more]
Ttbk25.540e-12361.67tau tubulin kinase 2 [Source:MGI Symbol;Acc:MGI:21... [more]
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BLAST of Protein kinase vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q8IMC6|ASATR_DROME1.410e-12966.78Tau-tubulin kinase homolog Asator OS=Drosophila me... [more]
sp|Q6PCN3|TTBK1_MOUSE2.239e-12763.73Tau-tubulin kinase 1 OS=Mus musculus OX=10090 GN=T... [more]
sp|Q5TCY1|TTBK1_HUMAN3.578e-12763.73Tau-tubulin kinase 1 OS=Homo sapiens OX=9606 GN=TT... [more]
sp|Q6IQ55|TTBK2_HUMAN7.828e-12361.18Tau-tubulin kinase 2 OS=Homo sapiens OX=9606 GN=TT... [more]
sp|Q3UVR3|TTBK2_MOUSE3.875e-12261.67Tau-tubulin kinase 2 OS=Mus musculus OX=10090 GN=T... [more]
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BLAST of Protein kinase vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
T1PJ517.486e-13964.50Protein kinase OS=Musca domestica OX=7370 GN=10189... [more]
A0A1I8P1Y94.976e-13864.17Protein kinase domain-containing protein OS=Stomox... [more]
A0A267DEE22.398e-13765.03Protein kinase domain-containing protein OS=Macros... [more]
A0A182SPC22.162e-13565.20Protein kinase domain-containing protein OS=Anophe... [more]
A0A1B6LDH82.279e-13555.15Protein kinase domain-containing protein (Fragment... [more]
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BLAST of Protein kinase vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ttbk1a5.117e-13161.59tau tubulin kinase 1a [Source:ZFIN;Acc:ZDB-GENE-10... [more]
ttbk1b2.114e-12962.67tau tubulin kinase 1b [Source:ZFIN;Acc:ZDB-GENE-10... [more]
ttbk2b4.117e-11758.28tau tubulin kinase 2b [Source:ZFIN;Acc:ZDB-GENE-03... [more]
ttbk2b3.117e-10252.98tau tubulin kinase 2b [Source:ZFIN;Acc:ZDB-GENE-03... [more]
csnk1db5.533e-4836.55casein kinase I [Source:NCBI gene;Acc:103030301][more]
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BLAST of Protein kinase vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ENSPMAT00000004926.14.413e-9755.83pep scaffold:Pmarinus_7.0:GL480178:196:11423:1 gen... [more]
ENSPMAT00000008477.15.895e-4635.49pep scaffold:Pmarinus_7.0:GL482342:316:9736:-1 gen... [more]
csnk1g2a3.407e-4533.67casein kinase 1, gamma 2a [Source:ZFIN;Acc:ZDB-GEN... [more]
csnk1g12.099e-3234.39casein kinase 1, gamma 1 [Source:NCBI gene;Acc:494... [more]
ENSPMAT00000001691.11.299e-2836.32pep scaffold:Pmarinus_7.0:GL476581:539457:546336:1... [more]
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BLAST of Protein kinase vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 5
Match NameE-valueIdentityDescription
HRR252.467e-4135.52Conserved casein kinase; regulates diverse events ... [more]
YCK12.780e-3730.00Palmitoylated plasma membrane-bound casein kinase ... [more]
YCK26.516e-3630.54Palmitoylated plasma membrane-bound casein kinase ... [more]
YCK36.435e-3029.14Palmitoylated vacuolar membrane-localized casein k... [more]
HOG17.858e-1226.94Mitogen-activated protein kinase involved in osmor... [more]
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BLAST of Protein kinase vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO467892.607e-11958.31Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO347421.378e-4836.68Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO487388.148e-4632.62Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO465232.811e-4432.92Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO342891.334e-4334.35Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Protein kinase vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ttbk2a1.436e-11855.39tau tubulin kinase 2 [Source:NCBI gene;Acc:1011741... [more]
ttbk1a5.310e-11657.32tau tubulin kinase 1 [Source:NCBI gene;Acc:1053541... [more]
ttbk2a7.157e-11150.29tau tubulin kinase 2 [Source:NCBI gene;Acc:1011741... [more]
ttbk2b5.371e-11055.29tau-tubulin kinase 2 [Source:NCBI gene;Acc:1011577... [more]
csnk1db1.721e-4736.55casein kinase 1 delta [Source:NCBI gene;Acc:101156... [more]
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BLAST of Protein kinase vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000030545.10.000e+099.74SMESG000030545.1[more]
SMESG000030545.10.000e+099.65SMESG000030545.1[more]
SMESG000048011.11.346e-14967.75SMESG000048011.1[more]
SMESG000026133.19.935e-13664.69SMESG000026133.1[more]
SMESG000068893.12.219e-13264.78SMESG000068893.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30028591 ID=SMED30028591|Name=Protein kinase|organism=Schmidtea mediterranea sexual|type=transcript|length=3499bp
TTCTAATATAACGGAAATGACGCACAATGCCATCAACGAAGCAAGAAACT
GATTTACTGAATCCAAGCAACATCGTTAAGGATCGATGGAAAGTAATTCG
GAAATTAGGCGGGGGAGGATTCGGTGAAATTTACGAATGTCTTGATTCAC
ACACCCAAGAAAAAGTAGCTTTAAAATTGGAATCGAGTCGAATAGCAAAA
CAAGTTTTAAAAATGGAAGTTGCCGTCTTGAAAAAGCTTCAAGGAACAGC
TCATGTTTGTAAGTTTCTCGGCTGTGGACGAAACGATCGATTCAATTATG
TTGCAATGACATTACAGGGAAAAAATCTTGCTGATTTACGAAGAGCTCAA
AAAAATTCCGCATTTTCGATTTCAACAATGTTGAGGCTAAGTGCTCAAAT
CCTTCAATCGATCCAAGATATACATAATTCTGGTTTTCTTCATCGAGACA
TTAAACCATCAAACTTTTCAATGGGTCGCTTACCATTATCATCTCACACT
GTTGTTATGCTTGATTTTGGGTTAGCACGTCAATACATATTACCTGATGG
TAATGGAGACATTAGAGCTCCTAGACCTGTTACAGGATTCAGAGGAACTG
TAAGGTATGCATCTGTTAACGCCCATATGAATCGAGAAATGGGGCGTCAT
GATGACTTATGGTCAGCTTTCTATATGATGGCAGAGATGGTTACCGGTAG
TTTACCGTGGAGAAAATTAAAGGATAAAGACCAAGTTGGTCAAATTAAAC
AAAACTTTGAACATACTCAACTATTAAGGCATTTACCTTCTGAATTCAAA
TTACTTCTTAGTCATATTCAAAGTTTAACTTATTTTGATGCTCCTGATTA
TGAATATTTAAAAAATCTTATTTATCAATGCATGCGTCGTAAAGGAATAA
GTTCCGATGAGTTGTTTGACTGGGAAACTACCAGTGATATTAGACAATCA
GTACAAAGCAGTAGTGTAACTGGAGGTAGAAACCCACACCATAATTTCCG
TAAAAAACCAACATCGAACATAGGCTCATTGAAAGACGGTGACAAGTCTA
ATAAAAATCAATCTATAAACATCCATCAAAAATCCAAAGTCATCACAAAT
CATAAACATAAGCCTTTGAAGTCAAATGATGAAACAGGGTTAGAAAGTGG
ACCTCGACCACCACCTAGAATAATGAAATCAACTAAACAGGAAGAATCAA
GCAAAATGAACGGAAAACAAATAATCAGCTTTCAAGAAGTTGTTGGAGCC
GATGATGAGAACTATGTTGAAGTCTATAACATTCCTAACAGAAATGGTAA
ACAAACAAAGCAATGTTTGGTTGAAGAATCGCTGAAAAATGTTCAAATGG
AAAATTATAGAAAAGAATCTACTACTGAATACAAAAAATTACATCGCAAT
ATATCGATAAAGAAATTAGAGAGGCAAGATTCTTTGAATAGTAAATATCA
TTCAAAACTACCAATTCTTTTAAAGTCCCAAAGCCGAGATAGCAGCCCTA
ATTATCTTGAAAGCAATGCTCAAACAAAACAATTAAAATCTTCCAATATG
AACTCATCCGGTCAGATGTATAAAGTTGCCAGAATTTCATCAATTACCGA
TTCGGCTTTCGTTGATATTGACAATAAACCGGCTGTAGCAAATATCGAAA
CTCAGAGACATTCTAAACAGTCTTTGAATATCACAAATATCGATCAAGAA
GACTACAACGCAGTCGAAGAAATTCAAGAGGCTTCTAAATCCCTCTCATG
TTCAAGTGATGATTACGAAAAAGAGTTTTCTCATCGATACAAGAATCGTA
AAGAAATCGACAAAGACAGCAGTCATCAAAAGATATCGGCGAGAATCGAA
GTAAACACAACCTCTCCAATTGAATTGAAACCCTTGCAATTAGATCAGAA
TACAAAGGCCAATCTCAACGATCCAATCCACCATCACAATCATCATCATC
ATCACATGTGTAAAAGCAAAATGGATAGTCTATCTCGACGAATTAGCGTT
GCGTTCAGTGTCGGCAGTCGAGCAACAAGAGCTATCAATGAAGACAAATT
TGATTATAGCAATGCCTATGACGCTACGAAAATGCTCCATTTAACGCACT
ACAGTGACAATTACGGCTACGATGACAAAGATATATCAGAAAATTTCCGT
GACGTTTTCATTGCCGATAATTCGTTACAAAAATCATCCTCGAAACATTC
AAGTCATAAAATGATGTTACACAATGAAAAGCTTCTATCAAATCAATCTC
GAAGTAAAGATGGATCTTTAGAATCTTTGAAATCCAAAAGCATCAAATCA
TTTACCAATAATAAATTCGAAAAGCAAAGTCTCTTTATCAACCCGTCCAA
ATCAATCAGTTGCAAATCATCGAAAATCTCCGCGTCTGACTATAGTAAAT
ATGCCAGCTTGAAAAAATCCTTTTCCCGTCAAGTCAGTGAAGAACTTCCG
CAACCATCTCAGTTTATTGATAATCACGCCAAATTGAATGCAGAAAATGA
TTTCTATGTAACTTGTGTAAATTCTCCCTCAGCTTGCGCATTTCCATCGT
CCAATAGAATTCCTCCGAAATGCAATGATCGAAAGCCCTATCGACAGAGA
TGCGGCTCCTCTCCTGTTCCCAATGTATTGCGGTGTTCTTTCAATGATCC
AGCGTGTAACGGTTATCCGGATAAAGCAAACGAATCAGCACCCACAGAAC
CAAATACAAATCAAAATCGGATTTTAATAACCTCTCACTGTGAAAAAGAC
TTCCAAAAAGCCGTTAATCGTGCAAATGCATGCGAAAGATATCTCGAGAA
TATTAGCGATCCGAATAAGAGTCGAATTCCAATCAATAGCACAGTAAAAC
CCACCAAAGAATCCAGCATCCTTCTCAATACGAATCGAAATAAATTTCCA
AATCAAAAATCATTTTCCAGACCGAATCGAACAATAACAAAAACTCCCGC
TTCGTTTATCGATCGCCAATCAAGGACCGATTCCATGAAGTCGAATTTTC
AAGAAAACAACCAAAGACGTCGAAGTGCAAGTCGAGATTCGATCGTAATG
CAGAAACATCATCCATGTTCCAATGTAAATACATTGTATTATTCTCAGAA
ACTGTCCAATTGCCGACTAACTAATTCCAATACTGATATCCATAAGCACT
CAACCGGTGGTACCAACGCTACTGCTGCCGGATGCGGAGCTTGCTCTATG
CGCAACAATCATAACAGTCAGCAGCAATCGGCTGGTAATCAAGAGTCACT
TCTATCAAAACCAATAAGACCTAGATCGCAGTCACTGAAAAATTCAATAA
TCTGCCGATCATACAATGATATTTTCGAATCAGTCATCACTATTCCTGCA
CTGATGCCGACTGAAAGATTAAAGTCTCACAATCAATTTCAACAGAACTT
GATCAGCTGCGAATCGATTGTCGACAAAGAAATAAAAGTGAAATGATAAT
TCTCCCATTTATATATATAAAATATATATATACATAAATATATATACAT
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protein sequence of SMED30028591-orf-1

>SMED30028591-orf-1 ID=SMED30028591-orf-1|Name=SMED30028591-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=1140bp
MPSTKQETDLLNPSNIVKDRWKVIRKLGGGGFGEIYECLDSHTQEKVALK
LESSRIAKQVLKMEVAVLKKLQGTAHVCKFLGCGRNDRFNYVAMTLQGKN
LADLRRAQKNSAFSISTMLRLSAQILQSIQDIHNSGFLHRDIKPSNFSMG
RLPLSSHTVVMLDFGLARQYILPDGNGDIRAPRPVTGFRGTVRYASVNAH
MNREMGRHDDLWSAFYMMAEMVTGSLPWRKLKDKDQVGQIKQNFEHTQLL
RHLPSEFKLLLSHIQSLTYFDAPDYEYLKNLIYQCMRRKGISSDELFDWE
TTSDIRQSVQSSSVTGGRNPHHNFRKKPTSNIGSLKDGDKSNKNQSINIH
QKSKVITNHKHKPLKSNDETGLESGPRPPPRIMKSTKQEESSKMNGKQII
SFQEVVGADDENYVEVYNIPNRNGKQTKQCLVEESLKNVQMENYRKESTT
EYKKLHRNISIKKLERQDSLNSKYHSKLPILLKSQSRDSSPNYLESNAQT
KQLKSSNMNSSGQMYKVARISSITDSAFVDIDNKPAVANIETQRHSKQSL
NITNIDQEDYNAVEEIQEASKSLSCSSDDYEKEFSHRYKNRKEIDKDSSH
QKISARIEVNTTSPIELKPLQLDQNTKANLNDPIHHHNHHHHHMCKSKMD
SLSRRISVAFSVGSRATRAINEDKFDYSNAYDATKMLHLTHYSDNYGYDD
KDISENFRDVFIADNSLQKSSSKHSSHKMMLHNEKLLSNQSRSKDGSLES
LKSKSIKSFTNNKFEKQSLFINPSKSISCKSSKISASDYSKYASLKKSFS
RQVSEELPQPSQFIDNHAKLNAENDFYVTCVNSPSACAFPSSNRIPPKCN
DRKPYRQRCGSSPVPNVLRCSFNDPACNGYPDKANESAPTEPNTNQNRIL
ITSHCEKDFQKAVNRANACERYLENISDPNKSRIPINSTVKPTKESSILL
NTNRNKFPNQKSFSRPNRTITKTPASFIDRQSRTDSMKSNFQENNQRRRS
ASRDSIVMQKHHPCSNVNTLYYSQKLSNCRLTNSNTDIHKHSTGGTNATA
AGCGACSMRNNHNSQQQSAGNQESLLSKPIRPRSQSLKNSIICRSYNDIF
ESVITIPALMPTERLKSHNQFQQNLISCESIVDKEIKVK*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000017photoreceptor neuron
PLANA:0000020protonephridia
PLANA:0000099neuron
PLANA:0000101muscle cell
PLANA:0002075pigment cell
PLANA:0002089reproductive organ
Vocabulary: INTERPRO
TermDefinition
IPR000719Prot_kinase_dom
IPR017441Protein_kinase_ATP_BS
IPR011009Kinase-like_dom_sf
Vocabulary: biological process
TermDefinition
GO:0006468protein phosphorylation
GO:0016310phosphorylation
Vocabulary: molecular function
TermDefinition
GO:0005524ATP binding
GO:0004672protein kinase activity
GO:0016301kinase activity
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR000719Protein kinase domainSMARTSM00220serkin_6coord: 21..297
e-value: 9.0E-19
score: 78.4
IPR000719Protein kinase domainPFAMPF00069Pkinasecoord: 22..286
e-value: 3.2E-31
score: 108.7
IPR000719Protein kinase domainPROSITEPS50011PROTEIN_KINASE_DOMcoord: 21..286
score: 26.676
NoneNo IPR availableGENE3DG3DSA:1.10.510.10coord: 2..360
e-value: 6.5E-91
score: 307.3
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 958..996
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 958..1010
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 326..353
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 485..511
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 308..395
NoneNo IPR availablePANTHERPTHR11909CASEIN KINASE-RELATEDcoord: 5..303
NoneNo IPR availablePANTHERPTHR11909:SF201TAU-TUBULIN KINASE 2coord: 5..303
NoneNo IPR availableCDDcd14017STKc_TTBKcoord: 20..281
e-value: 3.71876E-147
score: 439.771
IPR017441Protein kinase, ATP binding sitePROSITEPS00107PROTEIN_KINASE_ATPcoord: 27..58
IPR011009Protein kinase-like domain superfamilySUPERFAMILYSSF56112Protein kinase-like (PK-like)coord: 16..300