Neuronal acetylcholine receptor subunit alpha-10

Overview
NameNeuronal acetylcholine receptor subunit alpha-10
Smed IDSMED30028579
Length (bp)1887
Neoblast Clusters

Zeng et. al., 2018




▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 



 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)




Explore this single cell expression dataset with our NB Cluster Shiny App




 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Neuronal acetylcholine receptor subunit alpha-10 (SMED30028579) t-SNE clustered cells

Violin plots show distribution of expression levels for Neuronal acetylcholine receptor subunit alpha-10 (SMED30028579) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Neuronal acetylcholine receptor subunit alpha-10 (SMED30028579) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Neuronal acetylcholine receptor subunit alpha-10 (SMED30028579) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017




Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020




SMED30028579

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 6

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
intestinal phagocyteSMED30028579h1SMcG0018250 Contig7381newmark_estsPMID:23079596
Forsthoefel et al., 2012
FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
intestinal phagocyteSMED30028579h1SMcG0018250 Contig7381uc_Smed_v2PMID:23079596
Forsthoefel et al., 2012
FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
head regionSMED30028579h1SMcG0018250 SmedASXL_005898SmedAsxl_ww_GCZZ01PMID:27034770
Currie et al., 2016
whole organism asexual adult RNA-sequencing evidence
nervous systemSMED30028579h1SMcG0018250 dd_Smed_v4_23922_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30028579h1SMcG0018250 dd_Smed_v4_23922_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
head regionSMED30028579h1SMcG0018250 dd_Smed_v6_23922_0_1dd_Smed_v6PMID:28171748
Stückemann et al., 2017
whole organism asexual adult RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
BLAST of Neuronal acetylcholine receptor subunit alpha-10 vs. Ensembl Human
Match: CHRNA7 (cholinergic receptor nicotinic alpha 7 subunit [Source:HGNC Symbol;Acc:HGNC:1960])

HSP 1 Score: 314.309 bits (804), Expect = 1.450e-99
Identity = 147/312 (47.12%), Postives = 207/312 (66.35%), Query Frame = 2
Query:  200 EHRLFKKLMKDYEPSVRPVRNSSKPVIAKMGITLTQIFDMDEKNQVLVTNVWLDQQWYDEYLQWNTSEFPSISKLRIPSEKIWKPDIVLYNNAADFADKMMPALAMVKNDGEVFWPVPTKLKSSCKIDVTYFPFDSQICTLKFGSWTYDGFQVELDKLKGVDLDMYVENGEWKLKKTKVLRNNIVYTCCPEPYYDVTFVLYLERRILYFIYHVIYPCIMMSTLTLLVFCLPPDSGEKIALGITVLLAFSVLMLSIAEKLPETSESVPLISIYLTTVMSMTSVSVIMTVFVLNLHHRGPNKSPIPKWMQRLMI 1135
            + +L+K+L+K+Y P  RPV N S+P+     ++L QI D+DEKNQVL TN+WL   W D YLQWN SE+P +  +R P  +IWKPDI+LYN+A +  D       +V + G   +  P   KSSC IDV +FPFD Q C LKFGSW+Y G+ ++L +++  D+  Y+ NGEW L      R+   Y CC EPY DVTF + + RR LY+  +++ PC+++S L LLVF LP DSGEKI+LGITVLL+ +V ML +AE +P TS+SVPLI+ Y  + M +  +SV++TV VL  HH  P+   +PKW + +++
Sbjct:   26 QRKLYKELVKNYNPLERPVANDSQPLTVYFSLSLLQIMDVDEKNQVLTTNIWLQMSWTDHYLQWNVSEYPGVKTVRFPDGQIWKPDILLYNSADERFDATFHTNVLVNSSGHCQYLPPGIFKSSCYIDVRWFPFDVQHCKLKFGSWSYGGWSLDL-QMQEADISGYIPNGEWDLVGIPGKRSERFYECCKEPYPDVTFTVTMRRRTLYYGLNLLIPCVLISALALLVFLLPADSGEKISLGITVLLSLTVFMLLVAEIMPATSDSVPLIAQYFASTMIIVGLSVVVTVIVLQYHHHDPDGGKMPKWTRVILL 336          
BLAST of Neuronal acetylcholine receptor subunit alpha-10 vs. Ensembl Human
Match: AC243734.1 (cholinergic receptor nicotinic alpha 7 subunit [Source:NCBI gene;Acc:1139])

HSP 1 Score: 314.309 bits (804), Expect = 1.450e-99
Identity = 147/312 (47.12%), Postives = 207/312 (66.35%), Query Frame = 2
Query:  200 EHRLFKKLMKDYEPSVRPVRNSSKPVIAKMGITLTQIFDMDEKNQVLVTNVWLDQQWYDEYLQWNTSEFPSISKLRIPSEKIWKPDIVLYNNAADFADKMMPALAMVKNDGEVFWPVPTKLKSSCKIDVTYFPFDSQICTLKFGSWTYDGFQVELDKLKGVDLDMYVENGEWKLKKTKVLRNNIVYTCCPEPYYDVTFVLYLERRILYFIYHVIYPCIMMSTLTLLVFCLPPDSGEKIALGITVLLAFSVLMLSIAEKLPETSESVPLISIYLTTVMSMTSVSVIMTVFVLNLHHRGPNKSPIPKWMQRLMI 1135
            + +L+K+L+K+Y P  RPV N S+P+     ++L QI D+DEKNQVL TN+WL   W D YLQWN SE+P +  +R P  +IWKPDI+LYN+A +  D       +V + G   +  P   KSSC IDV +FPFD Q C LKFGSW+Y G+ ++L +++  D+  Y+ NGEW L      R+   Y CC EPY DVTF + + RR LY+  +++ PC+++S L LLVF LP DSGEKI+LGITVLL+ +V ML +AE +P TS+SVPLI+ Y  + M +  +SV++TV VL  HH  P+   +PKW + +++
Sbjct:   26 QRKLYKELVKNYNPLERPVANDSQPLTVYFSLSLLQIMDVDEKNQVLTTNIWLQMSWTDHYLQWNVSEYPGVKTVRFPDGQIWKPDILLYNSADERFDATFHTNVLVNSSGHCQYLPPGIFKSSCYIDVRWFPFDVQHCKLKFGSWSYGGWSLDL-QMQEADISGYIPNGEWDLVGIPGKRSERFYECCKEPYPDVTFTVTMRRRTLYYGLNLLIPCVLISALALLVFLLPADSGEKISLGITVLLSLTVFMLLVAEIMPATSDSVPLIAQYFASTMIIVGLSVVVTVIVLQYHHHDPDGGKMPKWTRVILL 336          
BLAST of Neuronal acetylcholine receptor subunit alpha-10 vs. Ensembl Human
Match: CHRNA7 (cholinergic receptor nicotinic alpha 7 subunit [Source:HGNC Symbol;Acc:HGNC:1960])

HSP 1 Score: 313.923 bits (803), Expect = 5.248e-99
Identity = 147/312 (47.12%), Postives = 207/312 (66.35%), Query Frame = 2
Query:  200 EHRLFKKLMKDYEPSVRPVRNSSKPVIAKMGITLTQIFDMDEKNQVLVTNVWLDQQWYDEYLQWNTSEFPSISKLRIPSEKIWKPDIVLYNNAADFADKMMPALAMVKNDGEVFWPVPTKLKSSCKIDVTYFPFDSQICTLKFGSWTYDGFQVELDKLKGVDLDMYVENGEWKLKKTKVLRNNIVYTCCPEPYYDVTFVLYLERRILYFIYHVIYPCIMMSTLTLLVFCLPPDSGEKIALGITVLLAFSVLMLSIAEKLPETSESVPLISIYLTTVMSMTSVSVIMTVFVLNLHHRGPNKSPIPKWMQRLMI 1135
            + +L+K+L+K+Y P  RPV N S+P+     ++L QI D+DEKNQVL TN+WL   W D YLQWN SE+P +  +R P  +IWKPDI+LYN+A +  D       +V + G   +  P   KSSC IDV +FPFD Q C LKFGSW+Y G+ ++L +++  D+  Y+ NGEW L      R+   Y CC EPY DVTF + + RR LY+  +++ PC+++S L LLVF LP DSGEKI+LGITVLL+ +V ML +AE +P TS+SVPLI+ Y  + M +  +SV++TV VL  HH  P+   +PKW + +++
Sbjct:   55 QRKLYKELVKNYNPLERPVANDSQPLTVYFSLSLLQIMDVDEKNQVLTTNIWLQMSWTDHYLQWNVSEYPGVKTVRFPDGQIWKPDILLYNSADERFDATFHTNVLVNSSGHCQYLPPGIFKSSCYIDVRWFPFDVQHCKLKFGSWSYGGWSLDL-QMQEADISGYIPNGEWDLVGIPGKRSERFYECCKEPYPDVTFTVTMRRRTLYYGLNLLIPCVLISALALLVFLLPADSGEKISLGITVLLSLTVFMLLVAEIMPATSDSVPLIAQYFASTMIIVGLSVVVTVIVLQYHHHDPDGGKMPKWTRVILL 365          
BLAST of Neuronal acetylcholine receptor subunit alpha-10 vs. Ensembl Human
Match: AC254952.1 (cholinergic receptor nicotinic alpha 7 subunit [Source:NCBI gene;Acc:1139])

HSP 1 Score: 311.227 bits (796), Expect = 2.447e-98
Identity = 145/312 (46.47%), Postives = 206/312 (66.03%), Query Frame = 2
Query:  200 EHRLFKKLMKDYEPSVRPVRNSSKPVIAKMGITLTQIFDMDEKNQVLVTNVWLDQQWYDEYLQWNTSEFPSISKLRIPSEKIWKPDIVLYNNAADFADKMMPALAMVKNDGEVFWPVPTKLKSSCKIDVTYFPFDSQICTLKFGSWTYDGFQVELDKLKGVDLDMYVENGEWKLKKTKVLRNNIVYTCCPEPYYDVTFVLYLERRILYFIYHVIYPCIMMSTLTLLVFCLPPDSGEKIALGITVLLAFSVLMLSIAEKLPETSESVPLISIYLTTVMSMTSVSVIMTVFVLNLHHRGPNKSPIPKWMQRLMI 1135
            + +L+K+L+K+Y P  RPV N S+P+     ++L QI D+D+K QVL TN+WL   W D YLQWN SE+P +  +R P  +IWKPDI+LYN+A +  D       +V + G   +  P   KSSC IDV +FPFD Q C LKFGSW+Y G+ ++L +++  D+  Y+ NGEW L      R+   Y CC EPY DVTF + + RR LY+  +++ PC+++S L LLVF LP DSGEKI+LGITVLL+ +V ML +AE +P TS+SVPLI+ Y  + M +  +SV++TV VL  HH  P+   +PKW + +++
Sbjct:   26 QRKLYKELVKNYNPLERPVANDSQPLTVYFSLSLLQIMDVDQKRQVLTTNIWLQMSWTDHYLQWNVSEYPGVKTVRFPDGQIWKPDILLYNSADERFDATFHTNVLVNSSGHCQYLPPGIFKSSCYIDVRWFPFDVQHCKLKFGSWSYGGWSLDL-QMQEADISGYIPNGEWDLVGIPGKRSERFYECCKEPYPDVTFTVTMRRRTLYYGLNLLIPCVLISALALLVFLLPADSGEKISLGITVLLSLTVFMLLVAEIMPATSDSVPLIAQYFASTMIIVGLSVVVTVIVLQYHHHDPDGGKMPKWTRVILL 336          
BLAST of Neuronal acetylcholine receptor subunit alpha-10 vs. Ensembl Human
Match: AC254952.1 (cholinergic receptor nicotinic alpha 7 subunit [Source:NCBI gene;Acc:1139])

HSP 1 Score: 311.227 bits (796), Expect = 2.447e-98
Identity = 145/312 (46.47%), Postives = 206/312 (66.03%), Query Frame = 2
Query:  200 EHRLFKKLMKDYEPSVRPVRNSSKPVIAKMGITLTQIFDMDEKNQVLVTNVWLDQQWYDEYLQWNTSEFPSISKLRIPSEKIWKPDIVLYNNAADFADKMMPALAMVKNDGEVFWPVPTKLKSSCKIDVTYFPFDSQICTLKFGSWTYDGFQVELDKLKGVDLDMYVENGEWKLKKTKVLRNNIVYTCCPEPYYDVTFVLYLERRILYFIYHVIYPCIMMSTLTLLVFCLPPDSGEKIALGITVLLAFSVLMLSIAEKLPETSESVPLISIYLTTVMSMTSVSVIMTVFVLNLHHRGPNKSPIPKWMQRLMI 1135
            + +L+K+L+K+Y P  RPV N S+P+     ++L QI D+D+K QVL TN+WL   W D YLQWN SE+P +  +R P  +IWKPDI+LYN+A +  D       +V + G   +  P   KSSC IDV +FPFD Q C LKFGSW+Y G+ ++L +++  D+  Y+ NGEW L      R+   Y CC EPY DVTF + + RR LY+  +++ PC+++S L LLVF LP DSGEKI+LGITVLL+ +V ML +AE +P TS+SVPLI+ Y  + M +  +SV++TV VL  HH  P+   +PKW + +++
Sbjct:   26 QRKLYKELVKNYNPLERPVANDSQPLTVYFSLSLLQIMDVDQKRQVLTTNIWLQMSWTDHYLQWNVSEYPGVKTVRFPDGQIWKPDILLYNSADERFDATFHTNVLVNSSGHCQYLPPGIFKSSCYIDVRWFPFDVQHCKLKFGSWSYGGWSLDL-QMQEADISGYIPNGEWDLVGIPGKRSERFYECCKEPYPDVTFTVTMRRRTLYYGLNLLIPCVLISALALLVFLLPADSGEKISLGITVLLSLTVFMLLVAEIMPATSDSVPLIAQYFASTMIIVGLSVVVTVIVLQYHHHDPDGGKMPKWTRVILL 336          
BLAST of Neuronal acetylcholine receptor subunit alpha-10 vs. Ensembl Celegans
Match: acr-19 (AcetylCholine Receptor [Source:UniProtKB/TrEMBL;Acc:B3WFZ2])

HSP 1 Score: 304.679 bits (779), Expect = 1.112e-95
Identity = 139/310 (44.84%), Postives = 200/310 (64.52%), Query Frame = 2
Query:  197 EEHRLFKKLMKDYEPSVRPVRNSSKPVIAKMGITLTQIFDMDEKNQVLVTNVWLDQQWYDEYLQWNTSEFPSISKLRIPSEKIWKPDIVLYNNAADFADKMMPALAMVKNDGEVFWPVPTKLKSSCKIDVTYFPFDSQICTLKFGSWTYDGFQVELDKLKGVDLDMYVENGEWKLKKTKVLRNNIVYTCCPEPYYDVTFVLYLERRILYFIYHVIYPCIMMSTLTLLVFCLPPDSGEKIALGITVLLAFSVLMLSIAEKLPETSESVPLISIYLTTVMSMTSVSVIMTVFVLNLHHRGPNK-SPIPKWMQ 1123
             E RL+ KL ++Y    RPVRN S+ V+  +G+   QI D+DEK+Q++ +NVWL   W D YL W+ SEF +I ++R+P   IWKPD++LYN+     D   P  A+V   G V W  P  ++SSC ID+ YFPFD+Q CT+KFGSWTY GF  +L     +    Y  NGEW+L      R+   Y CCPEPYYDVTF + + RR LY+ ++++ PC+++S+L LL F LP D GEK+ LG+T+ ++  V M+ +AE +P+TS+++PLI IY + +M     SV+ TV  LN HHR P +  P+ K+++
Sbjct:   24 HERRLYAKLAENYNKLARPVRNESEAVVVLLGMDYQQILDIDEKHQIMNSNVWLRMSWTDHYLTWDPSEFGNIKEVRLPINNIWKPDVLLYNSVDQQFDSTWPVNAVVLYTGNVTWIPPAIIRSSCAIDIAYFPFDTQHCTMKFGSWTYSGFFTDLINTT-ISPATYKPNGEWELLGLTSQRSIFFYECCPEPYYDVTFTVSIRRRTLYYGFNLLLPCMLISSLALLSFTLPADCGEKLNLGVTIFMSLCVFMIMVAEAMPQTSDALPLIQIYFSCIMFQVGASVVATVIALNFHHRSPEQYKPMNKFLK 332          
BLAST of Neuronal acetylcholine receptor subunit alpha-10 vs. Ensembl Celegans
Match: acr-19 (AcetylCholine Receptor [Source:UniProtKB/TrEMBL;Acc:B3WFZ2])

HSP 1 Score: 304.679 bits (779), Expect = 1.502e-95
Identity = 139/310 (44.84%), Postives = 200/310 (64.52%), Query Frame = 2
Query:  197 EEHRLFKKLMKDYEPSVRPVRNSSKPVIAKMGITLTQIFDMDEKNQVLVTNVWLDQQWYDEYLQWNTSEFPSISKLRIPSEKIWKPDIVLYNNAADFADKMMPALAMVKNDGEVFWPVPTKLKSSCKIDVTYFPFDSQICTLKFGSWTYDGFQVELDKLKGVDLDMYVENGEWKLKKTKVLRNNIVYTCCPEPYYDVTFVLYLERRILYFIYHVIYPCIMMSTLTLLVFCLPPDSGEKIALGITVLLAFSVLMLSIAEKLPETSESVPLISIYLTTVMSMTSVSVIMTVFVLNLHHRGPNK-SPIPKWMQ 1123
             E RL+ KL ++Y    RPVRN S+ V+  +G+   QI D+DEK+Q++ +NVWL   W D YL W+ SEF +I ++R+P   IWKPD++LYN+     D   P  A+V   G V W  P  ++SSC ID+ YFPFD+Q CT+KFGSWTY GF  +L     +    Y  NGEW+L      R+   Y CCPEPYYDVTF + + RR LY+ ++++ PC+++S+L LL F LP D GEK+ LG+T+ ++  V M+ +AE +P+TS+++PLI IY + +M     SV+ TV  LN HHR P +  P+ K+++
Sbjct:   30 HERRLYAKLAENYNKLARPVRNESEAVVVLLGMDYQQILDIDEKHQIMNSNVWLRMSWTDHYLTWDPSEFGNIKEVRLPINNIWKPDVLLYNSVDQQFDSTWPVNAVVLYTGNVTWIPPAIIRSSCAIDIAYFPFDTQHCTMKFGSWTYSGFFTDLIN-TTISPATYKPNGEWELLGLTSQRSIFFYECCPEPYYDVTFTVSIRRRTLYYGFNLLLPCMLISSLALLSFTLPADCGEKLNLGVTIFMSLCVFMIMVAEAMPQTSDALPLIQIYFSCIMFQVGASVVATVIALNFHHRSPEQYKPMNKFLK 338          
BLAST of Neuronal acetylcholine receptor subunit alpha-10 vs. Ensembl Celegans
Match: acr-16 (Acetylcholine receptor subunit alpha-type acr-16 [Source:UniProtKB/Swiss-Prot;Acc:P48180])

HSP 1 Score: 302.753 bits (774), Expect = 1.553e-95
Identity = 144/314 (45.86%), Postives = 200/314 (63.69%), Query Frame = 2
Query:  197 EEHRLFKKLMKDYEPSVRPVRNSSKPVIAKMGITLTQIFDMDEKNQVLVTNVWLDQQWYDEYLQWNTSEFPSISKLRIPSEKIWKPDIVLYNNAADFADKMMPALAMVKNDGEVFWPVPTKLKSSCKIDVTYFPFDSQICTLKFGSWTYDGFQVELD-KLKGVDLDMYVENGEWKLKKTKVLRNNIVYTCCPEPYYDVTFVLYLERRILYFIYHVIYPCIMMSTLTLLVFCLPPDSGEKIALGITVLLAFSVLMLSIAEKLPETSESVPLISIYLTTVMSMTSVSVIMTVFVLNLHHRGPNKSPIPKWMQRLMI 1135
            +E RL++ LM++Y    RPV N S+PV   + + L QI D+DEKNQV+  N WLD  W D  L W+ +E+ +I+ +R P+ KIWKPD++LYN+     D       +V + G V W  P   K SCKID+ +FPFD Q C  KFGSWTYDG++++L     G D+  Y+ NGEW L  T V RN   Y CCPEPY DV F L++ RR LY+ +++I PCI+ + +TLL F LPPD+GEKI L ITVLL+    +  ++E  P TSE+VPL+ I+ T  M + + S + TV+VLNLH+R P    +  W + L++
Sbjct:   22 QERRLYEDLMRNYNNLERPVANHSEPVTVHLKVALQQIIDVDEKNQVVYVNAWLDYTWNDYNLVWDKAEYGNITDVRFPAGKIWKPDVLLYNSVDTNFDSTYQTNMIVYSTGLVHWVPPGIFKISCKIDIQWFPFDEQKCFFKFGSWTYDGYKLDLQPATGGFDISEYISNGEWALPLTTVERNEKFYDCCPEPYPDVHFYLHMRRRTLYYGFNLIMPCILTTLMTLLGFTLPPDAGEKITLQITVLLSICFFLSIVSEMSPPTSEAVPLLGIFFTCCMIVVTASTVFTVYVLNLHYRTPETHDMGPWTRNLLL 335          
BLAST of Neuronal acetylcholine receptor subunit alpha-10 vs. Ensembl Celegans
Match: acr-21 (pep chromosome:WBcel235:III:6581927:6586549:1 gene:WBGene00000060.1 transcript:F27B3.2a.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:acr-21)

HSP 1 Score: 293.893 bits (751), Expect = 1.468e-90
Identity = 140/354 (39.55%), Postives = 219/354 (61.86%), Query Frame = 2
Query:  101 LANIYGLILILIVNRNTEGKSLSEVKNDENLPEEHRLFKKLMKDYEPSVRPVRNSSKPVIAKMGITLTQIFDMDEKNQVLVTNVWLDQQWYDEYLQWNTSEFPSISKLRIPSEKIWKPDIVLYNNA-ADFADKMMPALAMVKNDGEVFWPVPTKLKSSCKIDVTYFPFDSQICTLKFGSWTYDGFQVELD-KLKGVDLDMYVENGEWKLKKTKVLRNNIVYTCCPEPYYDVTFVLYLERRILYFIYHVIYPCIMMSTLTLLVFCLPPDSGEKIALGITVLLAFSVLMLSIAEKLPETSESVPLISIYLTTVMSMTSVSVIMTVFVLNLHHRGPNKSPIPKWMQRLMICKNRYFS 1156
            L  IY + L L  N    G  LS  + D+N+    RL++ L+ DY   VRP  +S +P+      +LTQI D+DE+NQ+L TN W+   W D  L W+   + +++++ IPS+KIWKPDI+LYNNA A +   +M    +V   G + WP+     SSC +DV ++PFD Q C LK+ SW YDG +++L  K +  DL  Y+ N EW L   +  +N ++Y+CCPEPY  +   + +ERR +++++++I PC+++S + L+ F +P DSGEK+ LGIT LL+ +V ++ +AE +P T+E++PLI IY    + + ++   MTVF +N+HH G +  P+P ++Q   I   RY S
Sbjct:    2 LTAIYNISLFLFFNGAHGGNELSS-RADQNV---MRLYRDLLYDYNNEVRPSVHSKEPINVTFVFSLTQIIDVDERNQILTTNSWIRLHWVDYKLVWDPRLYQNVTRIHIPSDKIWKPDIILYNNADAQYMKSVMSTDVIVDYLGNIHWPLSAIFTSSCPLDVKHYPFDRQTCILKYASWAYDGTKIDLLLKSEQGDLTNYITNTEWSLIGIRAEKNQVIYSCCPEPYPFIDVHVTIERRAMFYVFNLILPCVLISLIALMGFYMPTDSGEKVTLGITSLLSTTVFLMMVAEGMPPTAEALPLIGIYFGVTIMLVALGTAMTVFTVNIHHTGVHGYPVPPFLQ---IFAFRYLS 348          
BLAST of Neuronal acetylcholine receptor subunit alpha-10 vs. Ensembl Celegans
Match: acr-21 (pep chromosome:WBcel235:III:6581927:6586549:1 gene:WBGene00000060.1 transcript:F27B3.2b.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:acr-21)

HSP 1 Score: 293.123 bits (749), Expect = 1.559e-90
Identity = 140/354 (39.55%), Postives = 219/354 (61.86%), Query Frame = 2
Query:  101 LANIYGLILILIVNRNTEGKSLSEVKNDENLPEEHRLFKKLMKDYEPSVRPVRNSSKPVIAKMGITLTQIFDMDEKNQVLVTNVWLDQQWYDEYLQWNTSEFPSISKLRIPSEKIWKPDIVLYNNA-ADFADKMMPALAMVKNDGEVFWPVPTKLKSSCKIDVTYFPFDSQICTLKFGSWTYDGFQVELD-KLKGVDLDMYVENGEWKLKKTKVLRNNIVYTCCPEPYYDVTFVLYLERRILYFIYHVIYPCIMMSTLTLLVFCLPPDSGEKIALGITVLLAFSVLMLSIAEKLPETSESVPLISIYLTTVMSMTSVSVIMTVFVLNLHHRGPNKSPIPKWMQRLMICKNRYFS 1156
            L  IY + L L  N    G  LS  + D+N+    RL++ L+ DY   VRP  +S +P+      +LTQI D+DE+NQ+L TN W+   W D  L W+   + +++++ IPS+KIWKPDI+LYNNA A +   +M    +V   G + WP+     SSC +DV ++PFD Q C LK+ SW YDG +++L  K +  DL  Y+ N EW L   +  +N ++Y+CCPEPY  +   + +ERR +++++++I PC+++S + L+ F +P DSGEK+ LGIT LL+ +V ++ +AE +P T+E++PLI IY    + + ++   MTVF +N+HH G +  P+P ++Q   I   RY S
Sbjct:    2 LTAIYNISLFLFFNGAHGGNELSS-RADQNV---MRLYRDLLYDYNNEVRPSVHSKEPINVTFVFSLTQIIDVDERNQILTTNSWIRLHWVDYKLVWDPRLYQNVTRIHIPSDKIWKPDIILYNNADAQYMKSVMSTDVIVDYLGNIHWPLSAIFTSSCPLDVKHYPFDRQTCILKYASWAYDGTKIDLLLKSEQGDLTNYITNTEWSLIGIRAEKNQVIYSCCPEPYPFIDVHVTIERRAMFYVFNLILPCVLISLIALMGFYMPTDSGEKVTLGITSLLSTTVFLMMVAEGMPPTAEALPLIGIYFGVTIMLVALGTAMTVFTVNIHHTGVHGYPVPPFLQ---IFAFRYLS 348          
BLAST of Neuronal acetylcholine receptor subunit alpha-10 vs. Ensembl Fly
Match: nAChRalpha7 (gene:FBgn0086778 transcript:FBtr0301835)

HSP 1 Score: 326.635 bits (836), Expect = 6.802e-104
Identity = 146/344 (42.44%), Postives = 221/344 (64.24%), Query Frame = 2
Query:  110 IYGLILILIVNRNTEGKSLSEVKNDENLPEEHRLFKKLMKDYEPSVRPVRNSSKPVIAKMGITLTQIFDMDEKNQVLVTNVWLDQQWYDEYLQWNTSEFPSISKLRIPSEKIWKPDIVLYNNAADFADKMMPALAMVKNDGEVFWPVPTKLKSSCKIDVTYFPFDSQICTLKFGSWTYDGFQ--VELDKLKGVDLDMYVENGEWKLKKTKVLRNNIVYTCCPEPYYDVTFVLYLERRILYFIYHVIYPCIMMSTLTLLVFCLPPDSGEKIALGITVLLAFSVLMLSIAEKLPETSESVPLISIYLTTVMSMTSVSVIMTVFVLNLHHRGPNKSPIPKWMQRLMI 1135
            +YGL L++++     G            P E RL   L+ +Y    RPV N S P+    G+TL QI D+DEKNQ+L+TN+WL  +W D  L+WN+SEF  +  LRIP  ++WKPD+++YN+A +  D       +V+N+G   +  P   KS+CKID+T+FPFD Q C +KFGSWTYDGFQ  ++L    G D+  ++ NGEW L      RN I Y CCPEPY D+TF + + R+ LY+ +++I PC++++++ LL F LPPDSGEK++LG+T+LL+ +V +  +AE +P TS++VPL+  Y   +M M + SV+ T+ +LN HHR P+   + +W++ + +
Sbjct:   43 VYGLGLLIMIPACAAG------------PHEKRLLHALLDNYNSLERPVVNESDPLQLSFGLTLMQIIDVDEKNQLLITNIWLKLEWNDMNLRWNSSEFGGVRDLRIPPHRLWKPDVLMYNSADEGFDGTYATNVVVRNNGSCLYVPPGIFKSTCKIDITWFPFDDQRCEMKFGSWTYDGFQLDLQLQDEAGGDISSFITNGEWDLLGVPGKRNEIYYNCCPEPYIDITFAILIRRKTLYYFFNLIVPCVLIASMALLGFTLPPDSGEKLSLGVTILLSLTVFLNMVAETMPATSDAVPLLGTYFNCIMFMVASSVVSTILILNYHHRNPDTHEMSEWIRVIFL 374          
BLAST of Neuronal acetylcholine receptor subunit alpha-10 vs. Ensembl Fly
Match: nAChRalpha7 (gene:FBgn0086778 transcript:FBtr0301834)

HSP 1 Score: 326.635 bits (836), Expect = 7.689e-104
Identity = 146/344 (42.44%), Postives = 221/344 (64.24%), Query Frame = 2
Query:  110 IYGLILILIVNRNTEGKSLSEVKNDENLPEEHRLFKKLMKDYEPSVRPVRNSSKPVIAKMGITLTQIFDMDEKNQVLVTNVWLDQQWYDEYLQWNTSEFPSISKLRIPSEKIWKPDIVLYNNAADFADKMMPALAMVKNDGEVFWPVPTKLKSSCKIDVTYFPFDSQICTLKFGSWTYDGFQ--VELDKLKGVDLDMYVENGEWKLKKTKVLRNNIVYTCCPEPYYDVTFVLYLERRILYFIYHVIYPCIMMSTLTLLVFCLPPDSGEKIALGITVLLAFSVLMLSIAEKLPETSESVPLISIYLTTVMSMTSVSVIMTVFVLNLHHRGPNKSPIPKWMQRLMI 1135
            +YGL L++++     G            P E RL   L+ +Y    RPV N S P+    G+TL QI D+DEKNQ+L+TN+WL  +W D  L+WN+SEF  +  LRIP  ++WKPD+++YN+A +  D       +V+N+G   +  P   KS+CKID+T+FPFD Q C +KFGSWTYDGFQ  ++L    G D+  ++ NGEW L      RN I Y CCPEPY D+TF + + R+ LY+ +++I PC++++++ LL F LPPDSGEK++LG+T+LL+ +V +  +AE +P TS++VPL+  Y   +M M + SV+ T+ +LN HHR P+   + +W++ + +
Sbjct:   43 VYGLGLLIMIPACAAG------------PHEKRLLHALLDNYNSLERPVVNESDPLQLSFGLTLMQIIDVDEKNQLLITNIWLKLEWNDMNLRWNSSEFGGVRDLRIPPHRLWKPDVLMYNSADEGFDGTYATNVVVRNNGSCLYVPPGIFKSTCKIDITWFPFDDQRCEMKFGSWTYDGFQLDLQLQDEAGGDISSFITNGEWDLLGVPGKRNEIYYNCCPEPYIDITFAILIRRKTLYYFFNLIVPCVLIASMALLGFTLPPDSGEKLSLGVTILLSLTVFLNMVAETMPATSDAVPLLGTYFNCIMFMVASSVVSTILILNYHHRNPDTHEMSEWIRVIFL 374          
BLAST of Neuronal acetylcholine receptor subunit alpha-10 vs. Ensembl Fly
Match: nAChRalpha7 (gene:FBgn0086778 transcript:FBtr0343798)

HSP 1 Score: 326.635 bits (836), Expect = 7.689e-104
Identity = 146/344 (42.44%), Postives = 221/344 (64.24%), Query Frame = 2
Query:  110 IYGLILILIVNRNTEGKSLSEVKNDENLPEEHRLFKKLMKDYEPSVRPVRNSSKPVIAKMGITLTQIFDMDEKNQVLVTNVWLDQQWYDEYLQWNTSEFPSISKLRIPSEKIWKPDIVLYNNAADFADKMMPALAMVKNDGEVFWPVPTKLKSSCKIDVTYFPFDSQICTLKFGSWTYDGFQ--VELDKLKGVDLDMYVENGEWKLKKTKVLRNNIVYTCCPEPYYDVTFVLYLERRILYFIYHVIYPCIMMSTLTLLVFCLPPDSGEKIALGITVLLAFSVLMLSIAEKLPETSESVPLISIYLTTVMSMTSVSVIMTVFVLNLHHRGPNKSPIPKWMQRLMI 1135
            +YGL L++++     G            P E RL   L+ +Y    RPV N S P+    G+TL QI D+DEKNQ+L+TN+WL  +W D  L+WN+SEF  +  LRIP  ++WKPD+++YN+A +  D       +V+N+G   +  P   KS+CKID+T+FPFD Q C +KFGSWTYDGFQ  ++L    G D+  ++ NGEW L      RN I Y CCPEPY D+TF + + R+ LY+ +++I PC++++++ LL F LPPDSGEK++LG+T+LL+ +V +  +AE +P TS++VPL+  Y   +M M + SV+ T+ +LN HHR P+   + +W++ + +
Sbjct:   43 VYGLGLLIMIPACAAG------------PHEKRLLHALLDNYNSLERPVVNESDPLQLSFGLTLMQIIDVDEKNQLLITNIWLKLEWNDMNLRWNSSEFGGVRDLRIPPHRLWKPDVLMYNSADEGFDGTYATNVVVRNNGSCLYVPPGIFKSTCKIDITWFPFDDQRCEMKFGSWTYDGFQLDLQLQDEAGGDISSFITNGEWDLLGVPGKRNEIYYNCCPEPYIDITFAILIRRKTLYYFFNLIVPCVLIASMALLGFTLPPDSGEKLSLGVTILLSLTVFLNMVAETMPATSDAVPLLGTYFNCIMFMVASSVVSTILILNYHHRNPDTHEMSEWIRVIFL 374          
BLAST of Neuronal acetylcholine receptor subunit alpha-10 vs. Ensembl Fly
Match: nAChRalpha7 (gene:FBgn0086778 transcript:FBtr0074680)

HSP 1 Score: 326.635 bits (836), Expect = 7.689e-104
Identity = 146/344 (42.44%), Postives = 221/344 (64.24%), Query Frame = 2
Query:  110 IYGLILILIVNRNTEGKSLSEVKNDENLPEEHRLFKKLMKDYEPSVRPVRNSSKPVIAKMGITLTQIFDMDEKNQVLVTNVWLDQQWYDEYLQWNTSEFPSISKLRIPSEKIWKPDIVLYNNAADFADKMMPALAMVKNDGEVFWPVPTKLKSSCKIDVTYFPFDSQICTLKFGSWTYDGFQ--VELDKLKGVDLDMYVENGEWKLKKTKVLRNNIVYTCCPEPYYDVTFVLYLERRILYFIYHVIYPCIMMSTLTLLVFCLPPDSGEKIALGITVLLAFSVLMLSIAEKLPETSESVPLISIYLTTVMSMTSVSVIMTVFVLNLHHRGPNKSPIPKWMQRLMI 1135
            +YGL L++++     G            P E RL   L+ +Y    RPV N S P+    G+TL QI D+DEKNQ+L+TN+WL  +W D  L+WN+SEF  +  LRIP  ++WKPD+++YN+A +  D       +V+N+G   +  P   KS+CKID+T+FPFD Q C +KFGSWTYDGFQ  ++L    G D+  ++ NGEW L      RN I Y CCPEPY D+TF + + R+ LY+ +++I PC++++++ LL F LPPDSGEK++LG+T+LL+ +V +  +AE +P TS++VPL+  Y   +M M + SV+ T+ +LN HHR P+   + +W++ + +
Sbjct:   43 VYGLGLLIMIPACAAG------------PHEKRLLHALLDNYNSLERPVVNESDPLQLSFGLTLMQIIDVDEKNQLLITNIWLKLEWNDMNLRWNSSEFGGVRDLRIPPHRLWKPDVLMYNSADEGFDGTYATNVVVRNNGSCLYVPPGIFKSTCKIDITWFPFDDQRCEMKFGSWTYDGFQLDLQLQDEAGGDISSFITNGEWDLLGVPGKRNEIYYNCCPEPYIDITFAILIRRKTLYYFFNLIVPCVLIASMALLGFTLPPDSGEKLSLGVTILLSLTVFLNMVAETMPATSDAVPLLGTYFNCIMFMVASSVVSTILILNYHHRNPDTHEMSEWIRVIFL 374          
BLAST of Neuronal acetylcholine receptor subunit alpha-10 vs. Ensembl Fly
Match: nAChRalpha5 (gene:FBgn0028875 transcript:FBtr0300594)

HSP 1 Score: 325.479 bits (833), Expect = 1.022e-100
Identity = 145/316 (45.89%), Postives = 210/316 (66.46%), Query Frame = 2
Query:  197 EEHRLFKKLMKDYEPSVRPVRNSSKPVIAKMGITLTQIFDMDEKNQVLVTNVWLDQQWYDEYLQWNTSEFPSISKLRIPSEKIWKPDIVLYNNAADFADKMMPALAMVKNDGEVFWPVPTKLKSSCKIDVTYFPFDSQICTLKFGSWTYDGFQ--VELDKLKGVDLDMYVENGEWKLKKTKVLRNNIVYTCCPEPYYDVTFVLYLERRILYFIYHVIYPCIMMSTLTLLVFCLPPDSGEKIALGITVLLAFSVLMLSIAEKLPETSESVPLISIYLTTVMSMTSVSVIMTVFVLNLHHRGPNKSPIPKWMQRLMIC 1138
             E RL   L+  Y    RPV N S P+    G+TL QI D+DEKNQ+LVTNVWL  +W D  L+WNTS++  +  LRIP  +IWKPD+++YN+A +  D       +V+N+G   +  P   KS+CKID+T+FPFD Q C +KFGSWTYDGFQ  ++L    G D+  YV NGEW+L      RN I Y CCPEPY D+TF + + RR LY+ +++I PC++++++ LL F LPPDSGEK++LG+T+LL+ +V +  +AE +P TS++VPL+  Y   +M M + SV+ T+ +LN HHR  +   + +W++ + +C
Sbjct:  312 HEKRLLHDLLDPYNTLERPVLNESDPLQLSFGLTLMQIIDVDEKNQLLVTNVWLKLEWNDMNLRWNTSDYGGVKDLRIPPHRIWKPDVLMYNSADEGFDGTYQTNVVVRNNGSCLYVPPGIFKSTCKIDITWFPFDDQRCEMKFGSWTYDGFQLDLQLQDETGGDISSYVLNGEWELLGVPGKRNEIYYNCCPEPYIDITFAIIIRRRTLYYFFNLIIPCVLIASMALLGFTLPPDSGEKLSLGVTILLSLTVFLNMVAETMPATSDAVPLLGTYFNCIMFMVASSVVSTILILNYHHRNADTHEMSEWIRIVFLC 627          
BLAST of Neuronal acetylcholine receptor subunit alpha-10 vs. Ensembl Zebrafish
Match: si:ch211-39a7.1 (si:ch211-39a7.1 [Source:ZFIN;Acc:ZDB-GENE-060503-606])

HSP 1 Score: 324.324 bits (830), Expect = 1.391e-102
Identity = 149/314 (47.45%), Postives = 211/314 (67.20%), Query Frame = 2
Query:  194 PEEHRLFKKLMKDYEPSVRPVRNSSKPVIAKMGITLTQIFDMDEKNQVLVTNVWLDQQWYDEYLQWNTSEFPSISKLRIPSEKIWKPDIVLYNNAADFADKMMPALAMVKNDGEVFWPVPTKLKSSCKIDVTYFPFDSQICTLKFGSWTYDGFQVELDKLKGVDLDMYVENGEWKLKKTKVLRNNIVYTCCPEPYYDVTFVLYLERRILYFIYHVIYPCIMMSTLTLLVFCLPPDSGEKIALGITVLLAFSVLMLSIAEKLPETSESVPLISIYLTTVMSMTSVSVIMTVFVLNLHHRGPNKSPIPKWMQRLMI 1135
            P +  L K L+KDY    RPV N S+P+   + ++L QI D+DEKNQVL TN+WL+  WYD YLQWN SE+P +  LR  ++++W PDI+LYN+A D  D    +  +V + G   +  P    S+C +DV +FPFD Q C LKFGSWT+DG+ ++L ++   D+  Y+ NGEW L      RN + Y CC EPY DVTFV+ + RR LY+  +++ PC+++S++TLL+F LP DSGEKI+LGITVLL+ +V ML +AE +P TS+S+PLI  Y  ++M +  +SVI TV VL  HH  PN   +PKW+Q +++
Sbjct:   23 PYQRTLLKNLLKDYNRMERPVANDSQPLTVFLSMSLIQIMDVDEKNQVLTTNIWLNMHWYDHYLQWNQSEYPGVKNLRFTTDQVWTPDILLYNSADDKFDSTFKSNVVVNSSGYCNYLPPGIFMSTCNVDVRWFPFDIQKCELKFGSWTFDGWLLDL-QMNEADISGYMPNGEWDLVGVPGTRNELFYDCCKEPYPDVTFVVTIRRRTLYYALNLLIPCVLLSSMTLLIFLLPADSGEKISLGITVLLSLTVFMLLVAEIMPATSDSIPLIGQYFASIMIIVGMSVIATVVVLQYHHHDPNGGNMPKWVQLVLL 335          
BLAST of Neuronal acetylcholine receptor subunit alpha-10 vs. Ensembl Zebrafish
Match: chrna7 (cholinergic receptor, nicotinic, alpha 7 (neuronal) [Source:ZFIN;Acc:ZDB-GENE-040108-3])

HSP 1 Score: 318.931 bits (816), Expect = 2.219e-101
Identity = 154/318 (48.43%), Postives = 208/318 (65.41%), Query Frame = 2
Query:  188 NLPEEH--RLFKKLMKDYEPSVRPVRNSSKPVIAKMGITLTQIFDMDEKNQVLVTNVWLDQQWYDEYLQWNTSEFPSISKLRIPSEKIWKPDIVLYNNAADFADKMMPALAMVKNDGEVFWPVPTKLKSSCKIDVTYFPFDSQICTLKFGSWTYDGFQVELDKLKGVDLDMYVENGEWKLKKTKVLRNNIVYTCCPEPYYDVTFVLYLERRILYFIYHVIYPCIMMSTLTLLVFCLPPDSGEKIALGITVLLAFSVLMLSIAEKLPETSESVPLISIYLTTVMSMTSVSVIMTVFVLNLHHRGPNKSPIPKWMQRLMI 1135
            +L  EH  RL++ LMKDY P  RPV N +  +     ++L QI D+DEKNQVL TN+WL   WYD YLQWN SE+P ++ +R P  +IWKPDI+LYN+A +  D       +V + G   +  P   KS+C IDV +FPFD Q C LKFGSWTY G+ ++L  +   D+  Y+ NGEW L +    RN   Y CC EPY DVTF + + RR LY+  +++ PC+++STL LLVF LP DSGEKI+LGITVLL+ +V ML +AE +P TS+SVPLI+ Y  T M +  +SVI TV+VL  H+  P    +PKW + +++
Sbjct:   21 SLQGEHQRRLYRDLMKDYNPLERPVFNDTHSLTVYFSMSLMQIMDVDEKNQVLTTNIWLQLYWYDYYLQWNASEYPGVTNVRFPDSQIWKPDILLYNSADERFDATFHTNVLVNSSGACQYLPPGIFKSTCYIDVRWFPFDLQRCDLKFGSWTYGGWSLDLQMIDA-DITGYIANGEWDLVEVPGRRNERFYDCCKEPYPDVTFTVVMRRRTLYYGLNLLIPCVLISTLALLVFLLPADSGEKISLGITVLLSLTVFMLLVAEIMPATSDSVPLIAQYFATTMVIVGLSVIATVWVLQYHYHDPEGGKMPKWTRVVLL 337          
BLAST of Neuronal acetylcholine receptor subunit alpha-10 vs. Ensembl Zebrafish
Match: chrna7 (cholinergic receptor, nicotinic, alpha 7 (neuronal) [Source:ZFIN;Acc:ZDB-GENE-040108-3])

HSP 1 Score: 318.546 bits (815), Expect = 2.530e-101
Identity = 154/318 (48.43%), Postives = 208/318 (65.41%), Query Frame = 2
Query:  188 NLPEEH--RLFKKLMKDYEPSVRPVRNSSKPVIAKMGITLTQIFDMDEKNQVLVTNVWLDQQWYDEYLQWNTSEFPSISKLRIPSEKIWKPDIVLYNNAADFADKMMPALAMVKNDGEVFWPVPTKLKSSCKIDVTYFPFDSQICTLKFGSWTYDGFQVELDKLKGVDLDMYVENGEWKLKKTKVLRNNIVYTCCPEPYYDVTFVLYLERRILYFIYHVIYPCIMMSTLTLLVFCLPPDSGEKIALGITVLLAFSVLMLSIAEKLPETSESVPLISIYLTTVMSMTSVSVIMTVFVLNLHHRGPNKSPIPKWMQRLMI 1135
            +L  EH  RL++ LMKDY P  RPV N +  +     ++L QI D+DEKNQVL TN+WL   WYD YLQWN SE+P ++ +R P  +IWKPDI+LYN+A +  D       +V + G   +  P   KS+C IDV +FPFD Q C LKFGSWTY G+ ++L  +   D+  Y+ NGEW L +    RN   Y CC EPY DVTF + + RR LY+  +++ PC+++STL LLVF LP DSGEKI+LGITVLL+ +V ML +AE +P TS+SVPLI+ Y  T M +  +SVI TV+VL  H+  P    +PKW + +++
Sbjct:   20 SLQGEHQRRLYRDLMKDYNPLERPVFNDTHSLTVYFSMSLMQIMDVDEKNQVLTTNIWLQLYWYDYYLQWNASEYPGVTNVRFPDSQIWKPDILLYNSADERFDATFHTNVLVNSSGACQYLPPGIFKSTCYIDVRWFPFDLQRCDLKFGSWTYGGWSLDLQMIDA-DITGYIANGEWDLVEVPGRRNERFYDCCKEPYPDVTFTVVMRRRTLYYGLNLLIPCVLISTLALLVFLLPADSGEKISLGITVLLSLTVFMLLVAEIMPATSDSVPLIAQYFATTMVIVGLSVIATVWVLQYHYHDPEGGKMPKWTRVVLL 336          
BLAST of Neuronal acetylcholine receptor subunit alpha-10 vs. Ensembl Zebrafish
Match: CR847523.3 (neuronal acetylcholine receptor subunit alpha-10-like [Source:NCBI gene;Acc:101882637])

HSP 1 Score: 315.849 bits (808), Expect = 3.125e-100
Identity = 139/311 (44.69%), Postives = 213/311 (68.49%), Query Frame = 2
Query:  206 RLFKKLMKDYEPSVRPVRNSSKPVIAKMGITLTQIFDMDEKNQVLVTNVWLDQQWYDEYLQWNTSEFPSISKLRIPSEKIWKPDIVLYNNAADFADKMMPALAMVKNDGEVFWPVPTKLKSSCKIDVTYFPFDSQICTLKFGSWTYDGFQVEL-DKLKGVDLDMYVENGEWKLKKTKVLRNNIVYTCCPEPYYDVTFVLYLERRILYFIYHVIYPCIMMSTLTLLVFCLPPDSGEKIALGITVLLAFSVLMLSIAEKLPETSESVPLISIYLTTVMSMTSVSVIMTVFVLNLHHRGPNKSPIPKWMQRLMI 1135
            +L K L  +Y  ++RPV +++  +   + ITL+QI DMDE+NQ+L T +W+ Q W+D YL WNT+++  +  +RIPS  +W+PD+VLYNNA D     M    ++++DG++ W  P   KSSCK+DV++FPFD Q C L FGSWT++G Q++L + L   DL  +VEN EW+++     +N I+Y CC +PY D+T+ L+L+RR  ++I++++ PC+M+S L  L F LP DSGEK++LG+TVLLA +V  L +AE +P  SE+VPLI  Y    M+M + S  +T+F++N+HH GP   P+P W +R ++
Sbjct:   19 KLLKDLFVNYTSALRPVEDTNNIINVTLQITLSQIIDMDERNQILTTYLWIRQVWFDAYLTWNTTDYDGLDTIRIPSSYVWRPDVVLYNNADDQFSSSMETNVVIRHDGQIMWDQPAITKSSCKVDVSFFPFDVQHCRLTFGSWTHNGNQMDLHNALDSADLADFVENVEWEVQGMPAKKNVILYGCCSDPYPDITYTLHLKRRASFYIFNLLIPCMMISFLAPLGFYLPADSGEKVSLGVTVLLALTVFQLLVAESMPP-SENVPLIGKYYIATMTMITASTALTIFIMNIHHCGPEAQPVPSWARRFIL 328          
BLAST of Neuronal acetylcholine receptor subunit alpha-10 vs. Ensembl Zebrafish
Match: FO907089.1 (neuronal acetylcholine receptor subunit alpha-7-like [Source:NCBI gene;Acc:101882451])

HSP 1 Score: 312.383 bits (799), Expect = 1.734e-98
Identity = 151/318 (47.48%), Postives = 206/318 (64.78%), Query Frame = 2
Query:  188 NLPEEH--RLFKKLMKDYEPSVRPVRNSSKPVIAKMGITLTQIFDMDEKNQVLVTNVWLDQQWYDEYLQWNTSEFPSISKLRIPSEKIWKPDIVLYNNAADFADKMMPALAMVKNDGEVFWPVPTKLKSSCKIDVTYFPFDSQICTLKFGSWTYDGFQVELDKLKGVDLDMYVENGEWKLKKTKVLRNNIVYTCCPEPYYDVTFVLYLERRILYFIYHVIYPCIMMSTLTLLVFCLPPDSGEKIALGITVLLAFSVLMLSIAEKLPETSESVPLISIYLTTVMSMTSVSVIMTVFVLNLHHRGPNKSPIPKWMQRLMI 1135
            +L  EH  RL++ LMK+Y P  RPV N S  +      +L QI D+DEKNQVL TN+WL   W D YL+WN S++P ++ +R P   IW+PDI+LYN+A +  D       +V + G   +  P   KS+C IDV +FPFD Q C LKFGSWTY G+ ++L  +   D+  Y+ NGEW L +    RN   Y CC EPY DVTF + + RR LY+  +++ PC+++STL LLVF LP DSGEKI+LGITVLL+ +V ML +AE +P TS+SVPLI+ Y  T M +  +SVI TV VL  H+  P+ + +PKW + L++
Sbjct:   51 SLQGEHQRRLYRDLMKNYNPLERPVYNDSHSLTVHFSFSLMQIMDVDEKNQVLTTNIWLQLYWTDYYLRWNMSDYPGVNTVRFPDSLIWRPDILLYNSADERFDATFHTNVLVNSSGYCQYLPPGIFKSTCYIDVRWFPFDVQRCDLKFGSWTYGGWALDLQMINA-DITGYIANGEWDLVEVPGRRNEKFYDCCKEPYPDVTFTVVMRRRTLYYGLNLLIPCVLISTLALLVFLLPADSGEKISLGITVLLSLTVFMLLVAEIMPATSDSVPLIAQYFATTMVIVGLSVIATVLVLQYHYHDPDGAKMPKWTRVLLL 367          
BLAST of Neuronal acetylcholine receptor subunit alpha-10 vs. Ensembl Xenopus
Match: ENSXETT00000021532.1 (cholinergic receptor, nicotinic alpha 7 [Source:NCBI gene;Acc:100493611])

HSP 1 Score: 321.242 bits (822), Expect = 2.822e-102
Identity = 152/312 (48.72%), Postives = 207/312 (66.35%), Query Frame = 2
Query:  200 EHRLFKKLMKDYEPSVRPVRNSSKPVIAKMGITLTQIFDMDEKNQVLVTNVWLDQQWYDEYLQWNTSEFPSISKLRIPSEKIWKPDIVLYNNAADFADKMMPALAMVKNDGEVFWPVPTKLKSSCKIDVTYFPFDSQICTLKFGSWTYDGFQVELDKLKGVDLDMYVENGEWKLKKTKVLRNNIVYTCCPEPYYDVTFVLYLERRILYFIYHVIYPCIMMSTLTLLVFCLPPDSGEKIALGITVLLAFSVLMLSIAEKLPETSESVPLISIYLTTVMSMTSVSVIMTVFVLNLHHRGPNKSPIPKWMQRLMI 1135
            + +L+K+LMK+Y P  RPV N S P+    G++L QI D+DEKNQVL TN+WL  QW D YLQWN SE+P +  +R P  +IWKPDI+LYN+A +  D       +V + G   +  P   KSSC IDV +FPFD Q C LKFGSWTY G+ ++L  L+  D+  Y+ NGEW L      R+   Y CC EPY DVTF + + RR LY+  +++ PC+++S L LLVF LP DSGEKI+LGITVLL+ +V ML +AE +P TS+SVPLI+ Y  + M +  +SV++TV VL  HH  P+   +PKW + +++
Sbjct:   28 QRKLYKELMKNYNPLERPVLNDSHPLTVYFGMSLMQIMDVDEKNQVLTTNIWLQMQWIDYYLQWNMSEYPGVKNVRFPDGQIWKPDILLYNSADERFDASFHTNVLVNSSGHCQYLPPGIFKSSCYIDVRWFPFDIQKCNLKFGSWTYGGWSLDLQMLES-DISEYISNGEWDLVGVPGKRSENYYECCKEPYLDVTFTIIMRRRTLYYGLNLLIPCVLISALALLVFLLPADSGEKISLGITVLLSLTVFMLLVAEIMPATSDSVPLIAQYFASTMIIVGLSVVVTVIVLQYHHHDPHGGNMPKWTRIILL 338          
BLAST of Neuronal acetylcholine receptor subunit alpha-10 vs. Ensembl Xenopus
Match: prepl (prolyl endopeptidase-like [Source:Xenbase;Acc:XB-GENE-981635])

HSP 1 Score: 307.375 bits (786), Expect = 5.680e-97
Identity = 138/312 (44.23%), Postives = 208/312 (66.67%), Query Frame = 2
Query:  203 HRLFKKLMKDYEPSVRPVRNSSKPVIAKMGITLTQIFDMDEKNQVLVTNVWLDQQWYDEYLQWNTSEFPSISKLRIPSEKIWKPDIVLYNNAADFADKMMPALAMVKNDGEVFWPVPTKLKSSCKIDVTYFPFDSQICTLKFGSWTYDGFQVE-LDKLKGVDLDMYVENGEWKLKKTKVLRNNIVYTCCPEPYYDVTFVLYLERRILYFIYHVIYPCIMMSTLTLLVFCLPPDSGEKIALGITVLLAFSVLMLSIAEKLPETSESVPLISIYLTTVMSMTSVSVIMTVFVLNLHHRGPNKSPIPKWMQRLMI 1135
            ++L   L  +Y  ++RPV +  K +   + +TL+QI DMDE+NQ+L+  +W+ Q W+D YL+WN  ++  +  +RIPS  +W+PDIVLYNNA D     M    +++ DG++ W  P   KSSCK+DV++FPFD Q C L FGSWTY+G Q++ L+ L   DL  +VEN EW++      ++ I Y CC EPY DVT+ L L+RR  ++I++++ PC+M+S L  L F LP DSGEK++LG+TVLLA +V  L +AE +P  SE+VPLI  Y    M+M + S  +T+F++N+HH GP   P+P+W ++ ++
Sbjct:   26 YKLMNDLFANYSNALRPVEDMDKAMNVTLQVTLSQIIDMDERNQILMAYLWIRQVWFDAYLRWNKEDYDGLDTIRIPSSYVWRPDIVLYNNADDQFTGSMETNVVIRYDGQIMWDSPAITKSSCKVDVSFFPFDGQQCRLTFGSWTYNGNQIDILNHLDTGDLTDFVENVEWEILGMPAKKSVITYGCCSEPYPDVTYTLILKRRASFYIFNLLLPCVMISFLAPLGFYLPADSGEKVSLGVTVLLALTVFQLLVAESMP-PSENVPLIGKYYIATMTMITASTALTIFIMNIHHCGPEAKPVPQWAKKFIL 336          
BLAST of Neuronal acetylcholine receptor subunit alpha-10 vs. Ensembl Xenopus
Match: CHRNA9 (cholinergic receptor, nicotinic alpha 9 [Source:NCBI gene;Acc:100493319])

HSP 1 Score: 301.597 bits (771), Expect = 5.895e-95
Identity = 144/354 (40.68%), Postives = 223/354 (62.99%), Query Frame = 2
Query:   77 MVWKSVFRLANIYGLILILIVNRNTEGKSLSEVKNDENLPEEHRLFKKLMKDYEPSVRPVRNSSKPVIAKMGITLTQIFDMDEKNQVLVTNVWLDQQWYDEYLQWNTSEFPSISKLRIPSEKIWKPDIVLYNNAADFADKMMPALAMVKNDGEVFWPVPTKLKSSCKIDVTYFPFDSQICTLKFGSWTYDGFQVE-LDKLKGVDLDMYVENGEWKLKKTKVLRNNIVYTCCPEPYYDVTFVLYLERRILYFIYHVIYPCIMMSTLTLLVFCLPPDSGEKIALGITVLLAFSVLMLSIAEKLPETSESVPLISIYLTTVMSMTSVSVIMTVFVLNLHHRGPNKSPIPKWMQRLMI 1135
            M++ S++   ++ G  +    N  +  K +   K          LF+ L +DY  ++RPV ++ K +   + ITL+QI D+DE+NQ+L   +W+   WYD YL+W+  E+  +  +RIPS  +W+PDIVLYN A D   + +    +++ DG++ W  P   KSSC +DV+YFPFD+Q C L FGSWTY+G QV+ ++ +   DL  +VEN EW+++    ++N I Y CC EPY D+TF L L+RR  ++I++++ PC+M+S L  L F LP DSGEK++LG+TVLLA +V  L +AE +P  SESVPLI  Y    M+M + S  +T+ ++N+H  GP   PIP+W + +++
Sbjct:    1 MIYSSLYVTESLTGFCVTQSDNVTSFFKGVESAKGKY----AQMLFRDLFEDYSNALRPVEDTDKALNVSLQITLSQIKDVDERNQILTAYLWIRLSWYDAYLKWDRDEYDGLDSIRIPSNMVWRPDIVLYNKADDEFSEPVNTNVVLRYDGKITWDSPAITKSSCVVDVSYFPFDNQQCNLTFGSWTYNGNQVDIINTMDSGDLSDFVENVEWEMQGMPAVKNVITYGCCSEPYPDITFTLILKRRSSFYIFNLLIPCVMISFLAPLGFYLPADSGEKVSLGVTVLLALTVFQLMVAESMPP-SESVPLIGKYYIATMTMITASTALTIIIMNIHLCGPEAKPIPRWARIVIL 349          
BLAST of Neuronal acetylcholine receptor subunit alpha-10 vs. Ensembl Xenopus
Match: CHRNA9 (cholinergic receptor, nicotinic alpha 9 [Source:NCBI gene;Acc:100493319])

HSP 1 Score: 301.982 bits (772), Expect = 7.241e-95
Identity = 144/354 (40.68%), Postives = 223/354 (62.99%), Query Frame = 2
Query:   77 MVWKSVFRLANIYGLILILIVNRNTEGKSLSEVKNDENLPEEHRLFKKLMKDYEPSVRPVRNSSKPVIAKMGITLTQIFDMDEKNQVLVTNVWLDQQWYDEYLQWNTSEFPSISKLRIPSEKIWKPDIVLYNNAADFADKMMPALAMVKNDGEVFWPVPTKLKSSCKIDVTYFPFDSQICTLKFGSWTYDGFQVE-LDKLKGVDLDMYVENGEWKLKKTKVLRNNIVYTCCPEPYYDVTFVLYLERRILYFIYHVIYPCIMMSTLTLLVFCLPPDSGEKIALGITVLLAFSVLMLSIAEKLPETSESVPLISIYLTTVMSMTSVSVIMTVFVLNLHHRGPNKSPIPKWMQRLMI 1135
            M++ S++   ++ G  +    N  +  K +   K          LF+ L +DY  ++RPV ++ K +   + ITL+QI D+DE+NQ+L   +W+   WYD YL+W+  E+  +  +RIPS  +W+PDIVLYN A D   + +    +++ DG++ W  P   KSSC +DV+YFPFD+Q C L FGSWTY+G QV+ ++ +   DL  +VEN EW+++    ++N I Y CC EPY D+TF L L+RR  ++I++++ PC+M+S L  L F LP DSGEK++LG+TVLLA +V  L +AE +P  SESVPLI  Y    M+M + S  +T+ ++N+H  GP   PIP+W + +++
Sbjct:    1 MIYSSLYVTESLTGFCVTQSDNVTSFFKGVESAKG----KYAQMLFRDLFEDYSNALRPVEDTDKALNVSLQITLSQIKDVDERNQILTAYLWIRLSWYDAYLKWDRDEYDGLDSIRIPSNMVWRPDIVLYNKADDEFSEPVNTNVVLRYDGKITWDSPAITKSSCVVDVSYFPFDNQQCNLTFGSWTYNGNQVDIINTMDSGDLSDFVENVEWEMQGMPAVKNVITYGCCSEPYPDITFTLILKRRSSFYIFNLLIPCVMISFLAPLGFYLPADSGEKVSLGVTVLLALTVFQLMVAESMPP-SESVPLIGKYYIATMTMITASTALTIIIMNIHLCGPEAKPIPRWARIVIL 349          
BLAST of Neuronal acetylcholine receptor subunit alpha-10 vs. Ensembl Xenopus
Match: CHRNA9 (cholinergic receptor, nicotinic alpha 9 [Source:NCBI gene;Acc:100493319])

HSP 1 Score: 300.827 bits (769), Expect = 1.109e-94
Identity = 138/310 (44.52%), Postives = 208/310 (67.10%), Query Frame = 2
Query:  209 LFKKLMKDYEPSVRPVRNSSKPVIAKMGITLTQIFDMDEKNQVLVTNVWLDQQWYDEYLQWNTSEFPSISKLRIPSEKIWKPDIVLYNNAADFADKMMPALAMVKNDGEVFWPVPTKLKSSCKIDVTYFPFDSQICTLKFGSWTYDGFQVE-LDKLKGVDLDMYVENGEWKLKKTKVLRNNIVYTCCPEPYYDVTFVLYLERRILYFIYHVIYPCIMMSTLTLLVFCLPPDSGEKIALGITVLLAFSVLMLSIAEKLPETSESVPLISIYLTTVMSMTSVSVIMTVFVLNLHHRGPNKSPIPKWMQRLMI 1135
            LF+ L +DY  ++RPV ++ K +   + ITL+QI D+DE+NQ+L   +W+   WYD YL+W+  E+  +  +RIPS  +W+PDIVLYN A D   + +    +++ DG++ W  P   KSSC +DV+YFPFD+Q C L FGSWTY+G QV+ ++ +   DL  +VEN EW+++    ++N I Y CC EPY D+TF L L+RR  ++I++++ PC+M+S L  L F LP DSGEK++LG+TVLLA +V  L +AE +P  SESVPLI  Y    M+M + S  +T+ ++N+H  GP   PIP+W + +++
Sbjct:   18 LFRDLFEDYSNALRPVEDTDKALNVSLQITLSQIKDVDERNQILTAYLWIRLSWYDAYLKWDRDEYDGLDSIRIPSNMVWRPDIVLYNKADDEFSEPVNTNVVLRYDGKITWDSPAITKSSCVVDVSYFPFDNQQCNLTFGSWTYNGNQVDIINTMDSGDLSDFVENVEWEMQGMPAVKNVITYGCCSEPYPDITFTLILKRRSSFYIFNLLIPCVMISFLAPLGFYLPADSGEKVSLGVTVLLALTVFQLMVAESMPP-SESVPLIGKYYIATMTMITASTALTIIIMNIHLCGPEAKPIPRWARIVIL 326          
BLAST of Neuronal acetylcholine receptor subunit alpha-10 vs. Ensembl Mouse
Match: Chrna7 (cholinergic receptor, nicotinic, alpha polypeptide 7 [Source:MGI Symbol;Acc:MGI:99779])

HSP 1 Score: 315.849 bits (808), Expect = 3.246e-100
Identity = 148/312 (47.44%), Postives = 206/312 (66.03%), Query Frame = 2
Query:  200 EHRLFKKLMKDYEPSVRPVRNSSKPVIAKMGITLTQIFDMDEKNQVLVTNVWLDQQWYDEYLQWNTSEFPSISKLRIPSEKIWKPDIVLYNNAADFADKMMPALAMVKNDGEVFWPVPTKLKSSCKIDVTYFPFDSQICTLKFGSWTYDGFQVELDKLKGVDLDMYVENGEWKLKKTKVLRNNIVYTCCPEPYYDVTFVLYLERRILYFIYHVIYPCIMMSTLTLLVFCLPPDSGEKIALGITVLLAFSVLMLSIAEKLPETSESVPLISIYLTTVMSMTSVSVIMTVFVLNLHHRGPNKSPIPKWMQRLMI 1135
            + RL+K+L+K+Y P  RPV N S+P+     ++L QI D+DEKNQVL TN+WL   W D YLQWN SE+P +  +R P  +IWKPDI+LYN+A +  D       +V   G   +  P   KSSC IDV +FPFD Q C LKFGSW+Y G+ ++L +++  D+  Y+ NGEW L      RN   Y CC EPY DVT+ + + RR LY+  +++ PC+++S L LLVF LP DSGEKI+LGITVLL+ +V ML +AE +P TS+SVPLI+ Y  + M +  +SV++TV VL  HH  P+   +PKW + +++
Sbjct:   26 QRRLYKELVKNYNPLERPVANDSQPLTVYFSLSLLQIMDVDEKNQVLTTNIWLQMSWTDHYLQWNMSEYPGVKNVRFPDGQIWKPDILLYNSADERFDATFHTNVLVNASGHCQYLPPGIFKSSCYIDVRWFPFDVQQCKLKFGSWSYGGWSLDL-QMQEADISSYIPNGEWDLMGIPGKRNEKFYECCKEPYPDVTYTVTMRRRTLYYGLNLLIPCVLISALALLVFLLPADSGEKISLGITVLLSLTVFMLLVAEIMPATSDSVPLIAQYFASTMIIVGLSVVVTVIVLRYHHHDPDGGKMPKWTRIILL 336          
BLAST of Neuronal acetylcholine receptor subunit alpha-10 vs. Ensembl Mouse
Match: Chrna3 (cholinergic receptor, nicotinic, alpha polypeptide 3 [Source:MGI Symbol;Acc:MGI:87887])

HSP 1 Score: 297.36 bits (760), Expect = 1.548e-93
Identity = 147/316 (46.52%), Postives = 211/316 (66.77%), Query Frame = 2
Query:  200 EHRLFKKLMKDYEPSVRPVRNSSKPVIAKMGITLTQIFDMDEKNQVLVTNVWLDQQWYDEYLQWNTSEFPSISKLRIPSEKIWKPDIVLYNNA-ADFA--DKMMPALAMVKNDGEVFWPVPTKLKSSCKIDVTYFPFDSQICTLKFGSWTYDGFQVELDKL-KGVDLDMYVENGEWKLKKTKVLRNNIVYTCCPEPYYDVTFVLYLERRILYFIYHVIYPCIMMSTLTLLVFCLPPDSGEKIALGITVLLAFSVLMLSIAEKLPETSESVPLISIYLTTVMSMTSVSVIMTVFVLNLHHRGPNKSPIPKWMQRLMI 1135
            EHRLF+ L +DY   +RPV N S PVI +  ++++Q+  +DE NQ++ TN+WL Q W D  L+W  S++  +  +R+P+EKIWKPDIVLYNNA  DF   DK     A++K  GEV W  P   KSSCKIDVTYFPFD Q CT+KFGSW+YD  +++L  +   ++L  Y E+GEW + K    ++ I Y CC E Y D+T+ LY+ R  L++  ++I PC+++S LT+LVF LP D GEK+ L I+VLL+ +V +L I E +P TS  +PLI  YL   M   ++S+++TVFVLN+H+R P    +P W++ + +
Sbjct:   29 EHRLFQYLFEDYNEIIRPVANVSHPVIIQFEVSMSQLVKVDEVNQIMETNLWLKQIWNDYKLKWKPSDYQGVEFMRVPAEKIWKPDIVLYNNADGDFQVDDKTK---ALLKYTGEVTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVLIGSSMNLKDYWESGEWAIIKAPGYKHEIKYNCCEEIYQDITYSLYIRRLPLFYTINLIIPCLLISFLTVLVFYLPSDCGEKVTLCISVLLSLTVFLLVITETIPSTSLVIPLIGEYLLFTMIFVTLSIVITVFVLNVHYRTPTTHTMPTWVKAVFL 341          
BLAST of Neuronal acetylcholine receptor subunit alpha-10 vs. Ensembl Mouse
Match: Chrna10 (cholinergic receptor, nicotinic, alpha polypeptide 10 [Source:MGI Symbol;Acc:MGI:3609260])

HSP 1 Score: 295.434 bits (755), Expect = 4.264e-93
Identity = 143/344 (41.57%), Postives = 209/344 (60.76%), Query Frame = 2
Query:  203 HRLFKKLMKDYEPSVRPVRNSSKPVIAKMGITLTQIFDMDEKNQVLVTNVWLDQQWYDEYLQWNTSEFPSISKLRIPSEKIWKPDIVLYNNAADFADKMMPALA----MVKNDGEVFWPVPTKLKSSCKIDVTYFPFDSQICTLKFGSWTYDGFQVELD-KLKGVDLDMYVENGEWKLKKTKVLRNNIVYTCCPEPYYDVTFVLYLERRILYFIYHVIYPCIMMSTLTLLVFCLPPDSGEKIALGITVLLAFSVLMLSIAEKLPETSESVPLISIYLTTVMSMTSVSVIMTVFVLNLHHRGPNKSPIPKWMQRLMICKNRYFSCKGSLTKNRKIPFKGIKNIES 1219
            H+LF+ L  +Y  ++RPV ++ + +   + +TL+QI DMDE+NQVL   +W+ Q+W D YL W+   +  +  +RIPS  +W+PDIVLYN     AD   PA A    +V++DG V W  P   +SSC++DV+ FPFD+Q C L FGSWT+ G Q+++  +     L  +VEN EW++      R  + Y CC EPY DVTF L L RR   ++ +++ PC+ +S L  L F LP DSGEK++LG+TVLLA +V  L +AE +P  +ESVPLI  Y    M+M + S  +T+ ++NLH+ GPN  P+P W + L++        KG   + R  P    K +ES
Sbjct:   31 HKLFRDLFANYTSALRPVADTDQTLNVTLEVTLSQIIDMDERNQVLTLYLWIRQEWTDAYLHWDPKAYGDLDAIRIPSSLVWRPDIVLYNK----ADTQPPASASTNVVVRHDGAVRWDAPAITRSSCRVDVSAFPFDAQRCGLTFGSWTHGGHQLDVRPRGTSASLADFVENVEWRVLGMPARRRVLTYGCCSEPYPDVTFTLLLRRRAAAYVCNLLLPCVFISLLAPLAFHLPADSGEKVSLGVTVLLALTVFQLILAESMPP-AESVPLIGKYYMATMTMVTFSTALTILIMNLHYCGPNAHPVPAWARVLLLGH----LAKGLCVRERGEPCGQSKPLES 365          
BLAST of Neuronal acetylcholine receptor subunit alpha-10 vs. Ensembl Mouse
Match: Chrna3 (cholinergic receptor, nicotinic, alpha polypeptide 3 [Source:MGI Symbol;Acc:MGI:87887])

HSP 1 Score: 296.59 bits (758), Expect = 5.866e-93
Identity = 147/316 (46.52%), Postives = 211/316 (66.77%), Query Frame = 2
Query:  200 EHRLFKKLMKDYEPSVRPVRNSSKPVIAKMGITLTQIFDMDEKNQVLVTNVWLDQQWYDEYLQWNTSEFPSISKLRIPSEKIWKPDIVLYNNA-ADFA--DKMMPALAMVKNDGEVFWPVPTKLKSSCKIDVTYFPFDSQICTLKFGSWTYDGFQVELDKL-KGVDLDMYVENGEWKLKKTKVLRNNIVYTCCPEPYYDVTFVLYLERRILYFIYHVIYPCIMMSTLTLLVFCLPPDSGEKIALGITVLLAFSVLMLSIAEKLPETSESVPLISIYLTTVMSMTSVSVIMTVFVLNLHHRGPNKSPIPKWMQRLMI 1135
            EHRLF+ L +DY   +RPV N S PVI +  ++++Q+  +DE NQ++ TN+WL Q W D  L+W  S++  +  +R+P+EKIWKPDIVLYNNA  DF   DK     A++K  GEV W  P   KSSCKIDVTYFPFD Q CT+KFGSW+YD  +++L  +   ++L  Y E+GEW + K    ++ I Y CC E Y D+T+ LY+ R  L++  ++I PC+++S LT+LVF LP D GEK+ L I+VLL+ +V +L I E +P TS  +PLI  YL   M   ++S+++TVFVLN+H+R P    +P W++ + +
Sbjct:   29 EHRLFQYLFEDYNEIIRPVANVSHPVIIQFEVSMSQLVKVDEVNQIMETNLWLKQIWNDYKLKWKPSDYQGVEFMRVPAEKIWKPDIVLYNNADGDFQVDDKTK---ALLKYTGEVTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVLIGSSMNLKDYWESGEWAIIKAPGYKHEIKYNCCEEIYQDITYSLYIRRLPLFYTINLIIPCLLISFLTVLVFYLPSDCGEKVTLCISVLLSLTVFLLVITETIPSTSLVIPLIGEYLLFTMIFVTLSIVITVFVLNVHYRTPTTHTMPTWVKAVFL 341          
BLAST of Neuronal acetylcholine receptor subunit alpha-10 vs. Ensembl Mouse
Match: Chrna3 (cholinergic receptor, nicotinic, alpha polypeptide 3 [Source:MGI Symbol;Acc:MGI:87887])

HSP 1 Score: 296.59 bits (758), Expect = 7.430e-93
Identity = 147/316 (46.52%), Postives = 211/316 (66.77%), Query Frame = 2
Query:  200 EHRLFKKLMKDYEPSVRPVRNSSKPVIAKMGITLTQIFDMDEKNQVLVTNVWLDQQWYDEYLQWNTSEFPSISKLRIPSEKIWKPDIVLYNNA-ADFA--DKMMPALAMVKNDGEVFWPVPTKLKSSCKIDVTYFPFDSQICTLKFGSWTYDGFQVELDKL-KGVDLDMYVENGEWKLKKTKVLRNNIVYTCCPEPYYDVTFVLYLERRILYFIYHVIYPCIMMSTLTLLVFCLPPDSGEKIALGITVLLAFSVLMLSIAEKLPETSESVPLISIYLTTVMSMTSVSVIMTVFVLNLHHRGPNKSPIPKWMQRLMI 1135
            EHRLF+ L +DY   +RPV N S PVI +  ++++Q+  +DE NQ++ TN+WL Q W D  L+W  S++  +  +R+P+EKIWKPDIVLYNNA  DF   DK     A++K  GEV W  P   KSSCKIDVTYFPFD Q CT+KFGSW+YD  +++L  +   ++L  Y E+GEW + K    ++ I Y CC E Y D+T+ LY+ R  L++  ++I PC+++S LT+LVF LP D GEK+ L I+VLL+ +V +L I E +P TS  +PLI  YL   M   ++S+++TVFVLN+H+R P    +P W++ + +
Sbjct:   34 EHRLFQYLFEDYNEIIRPVANVSHPVIIQFEVSMSQLVKVDEVNQIMETNLWLKQIWNDYKLKWKPSDYQGVEFMRVPAEKIWKPDIVLYNNADGDFQVDDKTK---ALLKYTGEVTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVLIGSSMNLKDYWESGEWAIIKAPGYKHEIKYNCCEEIYQDITYSLYIRRLPLFYTINLIIPCLLISFLTVLVFYLPSDCGEKVTLCISVLLSLTVFLLVITETIPSTSLVIPLIGEYLLFTMIFVTLSIVITVFVLNVHYRTPTTHTMPTWVKAVFL 346          
BLAST of Neuronal acetylcholine receptor subunit alpha-10 vs. UniProt/SwissProt
Match: sp|Q05941|ACHA7_RAT (Neuronal acetylcholine receptor subunit alpha-7 OS=Rattus norvegicus OX=10116 GN=Chrna7 PE=1 SV=2)

HSP 1 Score: 315.849 bits (808), Expect = 1.935e-99
Identity = 148/312 (47.44%), Postives = 206/312 (66.03%), Query Frame = 2
Query:  200 EHRLFKKLMKDYEPSVRPVRNSSKPVIAKMGITLTQIFDMDEKNQVLVTNVWLDQQWYDEYLQWNTSEFPSISKLRIPSEKIWKPDIVLYNNAADFADKMMPALAMVKNDGEVFWPVPTKLKSSCKIDVTYFPFDSQICTLKFGSWTYDGFQVELDKLKGVDLDMYVENGEWKLKKTKVLRNNIVYTCCPEPYYDVTFVLYLERRILYFIYHVIYPCIMMSTLTLLVFCLPPDSGEKIALGITVLLAFSVLMLSIAEKLPETSESVPLISIYLTTVMSMTSVSVIMTVFVLNLHHRGPNKSPIPKWMQRLMI 1135
            + RL+K+L+K+Y P  RPV N S+P+     ++L QI D+DEKNQVL TN+WL   W D YLQWN SE+P +  +R P  +IWKPDI+LYN+A +  D       +V   G   +  P   KSSC IDV +FPFD Q C LKFGSW+Y G+ ++L +++  D+  Y+ NGEW L      RN   Y CC EPY DVT+ + + RR LY+  +++ PC+++S L LLVF LP DSGEKI+LGITVLL+ +V ML +AE +P TS+SVPLI+ Y  + M +  +SV++TV VL  HH  P+   +PKW + +++
Sbjct:   26 QRRLYKELVKNYNPLERPVANDSQPLTVYFSLSLLQIMDVDEKNQVLTTNIWLQMSWTDHYLQWNMSEYPGVKNVRFPDGQIWKPDILLYNSADERFDATFHTNVLVNASGHCQYLPPGIFKSSCYIDVRWFPFDVQQCKLKFGSWSYGGWSLDL-QMQEADISSYIPNGEWDLMGIPGKRNEKFYECCKEPYPDVTYTVTMRRRTLYYGLNLLIPCVLISALALLVFLLPADSGEKISLGITVLLSLTVFMLLVAEIMPATSDSVPLIAQYFASTMIIVGLSVVVTVIVLRYHHHDPDGGKMPKWTRIILL 336          
BLAST of Neuronal acetylcholine receptor subunit alpha-10 vs. UniProt/SwissProt
Match: sp|P49582|ACHA7_MOUSE (Neuronal acetylcholine receptor subunit alpha-7 OS=Mus musculus OX=10090 GN=Chrna7 PE=2 SV=1)

HSP 1 Score: 315.849 bits (808), Expect = 2.271e-99
Identity = 148/312 (47.44%), Postives = 206/312 (66.03%), Query Frame = 2
Query:  200 EHRLFKKLMKDYEPSVRPVRNSSKPVIAKMGITLTQIFDMDEKNQVLVTNVWLDQQWYDEYLQWNTSEFPSISKLRIPSEKIWKPDIVLYNNAADFADKMMPALAMVKNDGEVFWPVPTKLKSSCKIDVTYFPFDSQICTLKFGSWTYDGFQVELDKLKGVDLDMYVENGEWKLKKTKVLRNNIVYTCCPEPYYDVTFVLYLERRILYFIYHVIYPCIMMSTLTLLVFCLPPDSGEKIALGITVLLAFSVLMLSIAEKLPETSESVPLISIYLTTVMSMTSVSVIMTVFVLNLHHRGPNKSPIPKWMQRLMI 1135
            + RL+K+L+K+Y P  RPV N S+P+     ++L QI D+DEKNQVL TN+WL   W D YLQWN SE+P +  +R P  +IWKPDI+LYN+A +  D       +V   G   +  P   KSSC IDV +FPFD Q C LKFGSW+Y G+ ++L +++  D+  Y+ NGEW L      RN   Y CC EPY DVT+ + + RR LY+  +++ PC+++S L LLVF LP DSGEKI+LGITVLL+ +V ML +AE +P TS+SVPLI+ Y  + M +  +SV++TV VL  HH  P+   +PKW + +++
Sbjct:   26 QRRLYKELVKNYNPLERPVANDSQPLTVYFSLSLLQIMDVDEKNQVLTTNIWLQMSWTDHYLQWNMSEYPGVKNVRFPDGQIWKPDILLYNSADERFDATFHTNVLVNASGHCQYLPPGIFKSSCYIDVRWFPFDVQQCKLKFGSWSYGGWSLDL-QMQEADISSYIPNGEWDLMGIPGKRNEKFYECCKEPYPDVTYTVTMRRRTLYYGLNLLIPCVLISALALLVFLLPADSGEKISLGITVLLSLTVFMLLVAEIMPATSDSVPLIAQYFASTMIIVGLSVVVTVIVLRYHHHDPDGGKMPKWTRIILL 336          
BLAST of Neuronal acetylcholine receptor subunit alpha-10 vs. UniProt/SwissProt
Match: sp|P22770|ACHA7_CHICK (Neuronal acetylcholine receptor subunit alpha-7 OS=Gallus gallus OX=9031 GN=CHRNA7 PE=1 SV=1)

HSP 1 Score: 314.694 bits (805), Expect = 4.844e-99
Identity = 147/312 (47.12%), Postives = 205/312 (65.71%), Query Frame = 2
Query:  200 EHRLFKKLMKDYEPSVRPVRNSSKPVIAKMGITLTQIFDMDEKNQVLVTNVWLDQQWYDEYLQWNTSEFPSISKLRIPSEKIWKPDIVLYNNAADFADKMMPALAMVKNDGEVFWPVPTKLKSSCKIDVTYFPFDSQICTLKFGSWTYDGFQVELDKLKGVDLDMYVENGEWKLKKTKVLRNNIVYTCCPEPYYDVTFVLYLERRILYFIYHVIYPCIMMSTLTLLVFCLPPDSGEKIALGITVLLAFSVLMLSIAEKLPETSESVPLISIYLTTVMSMTSVSVIMTVFVLNLHHRGPNKSPIPKWMQRLMI 1135
            + +L+K+L+K+Y P  RPV N S+P+     ++L QI D+DEKNQVL TN+WL   W D YLQWN SE+P +  +R P   IWKPDI+LYN+A +  D       +V + G   +  P   KSSC IDV +FPFD Q C LKFGSWTY G+ ++L +++  D+  Y+ NGEW L      R    Y CC EPY D+TF + + RR LY+  +++ PC+++S L LLVF LP DSGEKI+LGITVLL+ +V ML +AE +P TS+SVPLI+ Y  + M +  +SV++TV VL  HH  P+   +PKW + +++
Sbjct:   26 QRKLYKELLKNYNPLERPVANDSQPLTVYFTLSLMQIMDVDEKNQVLTTNIWLQMYWTDHYLQWNVSEYPGVKNVRFPDGLIWKPDILLYNSADERFDATFHTNVLVNSSGHCQYLPPGIFKSSCYIDVRWFPFDVQKCNLKFGSWTYGGWSLDL-QMQEADISGYISNGEWDLVGIPGKRTESFYECCKEPYPDITFTVTMRRRTLYYGLNLLIPCVLISALALLVFLLPADSGEKISLGITVLLSLTVFMLLVAEIMPATSDSVPLIAQYFASTMIIVGLSVVVTVIVLQYHHHDPDGGKMPKWTRVILL 336          
BLAST of Neuronal acetylcholine receptor subunit alpha-10 vs. UniProt/SwissProt
Match: sp|P36544|ACHA7_HUMAN (Neuronal acetylcholine receptor subunit alpha-7 OS=Homo sapiens OX=9606 GN=CHRNA7 PE=1 SV=5)

HSP 1 Score: 314.309 bits (804), Expect = 6.961e-99
Identity = 147/312 (47.12%), Postives = 207/312 (66.35%), Query Frame = 2
Query:  200 EHRLFKKLMKDYEPSVRPVRNSSKPVIAKMGITLTQIFDMDEKNQVLVTNVWLDQQWYDEYLQWNTSEFPSISKLRIPSEKIWKPDIVLYNNAADFADKMMPALAMVKNDGEVFWPVPTKLKSSCKIDVTYFPFDSQICTLKFGSWTYDGFQVELDKLKGVDLDMYVENGEWKLKKTKVLRNNIVYTCCPEPYYDVTFVLYLERRILYFIYHVIYPCIMMSTLTLLVFCLPPDSGEKIALGITVLLAFSVLMLSIAEKLPETSESVPLISIYLTTVMSMTSVSVIMTVFVLNLHHRGPNKSPIPKWMQRLMI 1135
            + +L+K+L+K+Y P  RPV N S+P+     ++L QI D+DEKNQVL TN+WL   W D YLQWN SE+P +  +R P  +IWKPDI+LYN+A +  D       +V + G   +  P   KSSC IDV +FPFD Q C LKFGSW+Y G+ ++L +++  D+  Y+ NGEW L      R+   Y CC EPY DVTF + + RR LY+  +++ PC+++S L LLVF LP DSGEKI+LGITVLL+ +V ML +AE +P TS+SVPLI+ Y  + M +  +SV++TV VL  HH  P+   +PKW + +++
Sbjct:   26 QRKLYKELVKNYNPLERPVANDSQPLTVYFSLSLLQIMDVDEKNQVLTTNIWLQMSWTDHYLQWNVSEYPGVKTVRFPDGQIWKPDILLYNSADERFDATFHTNVLVNSSGHCQYLPPGIFKSSCYIDVRWFPFDVQHCKLKFGSWSYGGWSLDL-QMQEADISGYIPNGEWDLVGIPGKRSERFYECCKEPYPDVTFTVTMRRRTLYYGLNLLIPCVLISALALLVFLLPADSGEKISLGITVLLSLTVFMLLVAEIMPATSDSVPLIAQYFASTMIIVGLSVVVTVIVLQYHHHDPDGGKMPKWTRVILL 336          
BLAST of Neuronal acetylcholine receptor subunit alpha-10 vs. UniProt/SwissProt
Match: sp|Q9I8C7|ACH10_CHICK (Neuronal acetylcholine receptor subunit alpha-10 OS=Gallus gallus OX=9031 GN=CHRNA10 PE=3 SV=1)

HSP 1 Score: 311.997 bits (798), Expect = 1.421e-98
Identity = 141/312 (45.19%), Postives = 203/312 (65.06%), Query Frame = 2
Query:  203 HRLFKKLMKDYEPSVRPVRNSSKPVIAKMGITLTQIFDMDEKNQVLVTNVWLDQQWYDEYLQWNTSEFPSISKLRIPSEKIWKPDIVLYNNAADFADKMMPALAMVKNDGEVFWPVPTKLKSSCKIDVTYFPFDSQICTLKFGSWTYDGFQVELDKLKGV-DLDMYVENGEWKLKKTKVLRNNIVYTCCPEPYYDVTFVLYLERRILYFIYHVIYPCIMMSTLTLLVFCLPPDSGEKIALGITVLLAFSVLMLSIAEKLPETSESVPLISIYLTTVMSMTSVSVIMTVFVLNLHHRGPNKSPIPKWMQRLMI 1135
            H+L   L  +Y  ++RP  ++ + +   + +TL+QI DMDE+NQVL + +W+ Q W D +L W+   +  I  +RIPS  +W+PDIVLYNNA +     M    ++++DG + W  P   KSSCK+DV+YFPFD Q C L FGSWTY+G Q++L  L    DL  +VEN EW++      RN + Y CC EPY DVT+ L L RR  ++I++++ PC+M+S L  L F LP DSGEK++LG+TVLLA +V  L +AE +P  SESVPLI  Y    M+M + S  +T+F++N+HH GP   P+P W +RL++
Sbjct:   33 HKLLHDLFANYSSALRPAEDTERALNVTLQVTLSQIIDMDERNQVLTSYLWVRQAWLDAHLAWDKDAYGGIDSIRIPSSYVWRPDIVLYNNADERFGGSMETNVVLRSDGHIMWDSPAITKSSCKVDVSYFPFDGQQCRLTFGSWTYNGNQIDLRNLLDTGDLTDFVENVEWEVLGMPATRNVVTYGCCSEPYPDVTYTLLLRRRASFYIFNLLLPCVMISFLAPLGFYLPADSGEKVSLGVTVLLALTVFQLLVAESMPP-SESVPLIGKYYIATMTMITASTALTIFIMNIHHCGPGARPVPPWARRLIL 343          
BLAST of Neuronal acetylcholine receptor subunit alpha-10 vs. TrEMBL
Match: A0A210QVT8 (Neuronal acetylcholine receptor subunit alpha-10 OS=Mizuhopecten yessoensis OX=6573 GN=KP79_PYT15060 PE=3 SV=1)

HSP 1 Score: 511.146 bits (1315), Expect = 2.800e-172
Identity = 267/554 (48.19%), Postives = 362/554 (65.34%), Query Frame = 2
Query:  134 IVNRNTEGKSLSEVKNDENLPEEHRLFKKLMKDYEPSVRPVRNSSKPVIAKMGITLTQIFDMDEKNQVLVTNVWLDQQWYDEYLQWNTSEFPSISKLRIPSEKIWKPDIVLYNNAADFADKMMPALAMVKNDGEVFWPVPTKLKSSCKIDVTYFPFDSQICTLKFGSWTYDGFQVEL-DKLKGVDLDMYVENGEWKLKKTKVLRNNIVYTCCPEPYYDVTFVLYLERRILYFIYHVIYPCIMMSTLTLLVFCLPPDSGEKIALGITVLLAFSVLMLSIAEKLPETSESVPLISIYLTTVMSMTSVSVIMTVFVLNLHHRGPNKSPIPKWMQRLMICKNRYFSCKGSLTKNRKIPFKGIKNIESLLMSINSK-LKQFPVKKSKSFPSPQNHVENYLNKYPNEVGLGNIKLNSYPTMETDVLSGSVTANHEYEPMFISDNDYRCTGNIIHXXXXXXXXXXXXXXXXNILINPSSPTVDKAVSTDAYPSCDNDQQEINTKILSALNRILVKHEIDESNYNLIQEWREVAQFVDRILFWLYLFXXXXXXIIVLIIAPV 1789
            +V+ + + + ++    ++++P+E RL   L+  YE SVRPVRN+SKPV+  MG+T+TQIFDMDEKNQVLVTN WLDQ W+DE+L W   +F +I+ LRIP +K+W PDIVLYNNAA++ D +MPA AMVKN+G+VFWPVPTKL+SSCK+DVTYFPFD Q C LKFGSWTYDG+QV++ ++ + VDL  YV NGEW+L + +V+RN ++Y CCPEP+ DVTF +++ RR LY++Y+V++PCIMMS LTLLVFCLPPDSGEKIALGITVLLAFSV ML++AE LPETSE VPLISIYLT VM++TS+SV+MTVFVLNLHHRGPN+  +P W++ L   + +   C               K   S L    SK ++   +K +         ++N   +  NE+ L N   ++  T       G+   +H       SD  +   G                  S + L     P + +  S +          + + +I+ AL RIL KHE  + +Y ++Q+WR VAQ VDRILFW++   T  ST+I+L+I P 
Sbjct:   45 VVHSSDDRQKMNHNIRNQSVPDEQRLMYYLLMGYEKSVRPVRNASKPVVVGMGLTMTQIFDMDEKNQVLVTNAWLDQGWHDEFLIWEPKDFNNITTLRIPCDKLWLPDIVLYNNAAEYTDGVMPANAMVKNNGDVFWPVPTKLQSSCKVDVTYFPFDDQSCRLKFGSWTYDGYQVDITNRSEEVDLSNYVVNGEWELLQVRVVRNVVIYPCCPEPFPDVTFYVHIRRRTLYYMYNVVFPCIMMSALTLLVFCLPPDSGEKIALGITVLLAFSVFMLAVAENLPETSEFVPLISIYLTIVMTLTSLSVMMTVFVLNLHHRGPNRVEVPPWIRTLCFGRMQSLLC-----------INDDKTFSSYLTPRESKFIRTMSLKVT---------LDNIAQELQNEIQLENGMADTVVTER----EGTTIHDHR-----TSDGRFNGDGRF-------------NAGSSDSLRRHMRPPLTRGHSNN----------KAHDEIIQALKRILEKHEKGDRDYEIVQDWRRVAQVVDRILFWIFFLGTFISTLIILVITPA 546          
BLAST of Neuronal acetylcholine receptor subunit alpha-10 vs. TrEMBL
Match: K1QFA0 (Neuronal acetylcholine receptor subunit alpha-2 OS=Crassostrea gigas OX=29159 GN=CGI_10020157 PE=3 SV=1)

HSP 1 Score: 504.597 bits (1298), Expect = 7.085e-170
Identity = 271/543 (49.91%), Postives = 357/543 (65.75%), Query Frame = 2
Query:  191 LPEEHRLFKKLMKDYEPSVRPVRNSSKPVIAKMGITLTQIFDM--------DEKNQVLVTNVWLDQQWYDEYLQWNTSEFPSISKLRIPSEKIWKPDIVLYNNAADFADKMMPALAMVKNDGEVFWPVPTKLKSSCKIDVTYFPFDSQICTLKFGSWTYDGFQVEL-DKLKGVDLDMYVENGEWKLKKTKVLRNNIVYTCCPEPYYDVTFVLYLERRILYFIYHVIYPCIMMSTLTLLVFCLPPDSGEKIALGITVLLAFSVLMLSIAEKLPETSESVPLISIYLTTVMSMTSVSVIMTVFVLNLHHRGPNKSPIPKWMQRLMICKNRYFSCKGSLTKNRKIPF--KGIKNIESLLMSINSKLKQFPVKKSKSFPSPQNHVENYLNKYPNEVGLGNIKLNSYPTMETDVLSGSVTANHEYEPMFISDNDYRCTGNIIHXXXXXXXXXXXXXXXXNILINPSSPTVDKAVSTDAYPSCDNDQQEINTKILSALNRILVKHEIDESNYNLIQEWREVAQFVDRILFWLYLFXXXXXXIIVLIIAP 1786
            +P+E RL   +++ YE +VRPV+N+S  VI KMG+TLTQIFDM        DEKNQVLVTNVWLDQ+W DE+L+W+  +F +++K+RIP  KIW PDIVLYNNAA++ D +M A AMV+++G VFWP+PTKL+SSCK+DVTYFPFD QIC +KFGSWTYDGFQV++ ++ + VDL  YV NGEW L   +V RN + YTCCPE + DVTF +++ RR LY++Y+VI+PCIMMS LTLLVFCLPPDSGEKIALGITVLLAFSV ML++AE LPETSE VPLISIYLT VMS+TSVSVIMTVFVLNLHHRGP+++ +P W++ +++   +   C G   KN +IP   +G + + +  MS+ + L                  EN   +  NE  L N  +      +T V  G  T  H         N+ RC                       +L N +     + +         N   + + +I+  L  IL KHE ++ +Y +IQEWR+VAQ VDRILFW++LF T +ST+I+L+I P
Sbjct:   61 VPDEQRLMNHILRGYEKAVRPVQNASTAVIVKMGLTLTQIFDMAITKAIAKDEKNQVLVTNVWLDQEWDDEFLKWDPLQFSNVTKIRIPCHKIWLPDIVLYNNAAEYTDGVMLANAMVEHNGNVFWPIPTKLQSSCKVDVTYFPFDDQICKMKFGSWTYDGFQVDITNRSQEVDLSNYVVNGEWVLISVRVQRNVVYYTCCPESFPDVTFFIHIRRRTLYYMYNVIFPCIMMSALTLLVFCLPPDSGEKIALGITVLLAFSVFMLAVAENLPETSEFVPLISIYLTIVMSLTSVSVIMTVFVLNLHHRGPSRNAVPAWIRGILLGPIQSILCVG---KNDRIPTGRQGSRFLRT--MSLRATL------------------ENIAQELQNEAQLENGVM-----ADTIVTDGQGTTLH---------NETRCD--------------------VRLLPNDNHQRPRRGIQV------KNLHTKSHEEIVRNLQSILDKHEKEDRDYEIIQEWRKVAQVVDRILFWIFLFGTLSSTLIILVITP 540          
BLAST of Neuronal acetylcholine receptor subunit alpha-10 vs. TrEMBL
Match: A0A1I8J982 (Uncharacterized protein OS=Macrostomum lignano OX=282301 PE=3 SV=1)

HSP 1 Score: 496.893 bits (1278), Expect = 1.689e-168
Identity = 236/317 (74.45%), Postives = 273/317 (86.12%), Query Frame = 2
Query:  221 LMKDYEPSVRPVRNSSKPVIAKMGITLTQIFDMDEKNQVLVTNVWLDQQWYDEYLQWNTSEFPSISKLRIPSEKIWKPDIVLYNNAADFADKMMPALAMVKNDGEVFWPVPTKLKSSCKIDVTYFPFDSQICTLKFGSWTYDGFQVELDKLKG-VDLDMYVENGEWKLKKTKVL----RNNIVYTCCPEPYYDVTFVLYLERRILYFIYHVIYPCIMMSTLTLLVFCLPPDSGEKIALGITVLLAFSVLMLSIAEKLPETSESVPLISIYLTTVMSMTSVSVIMTVFVLNLHHRGPNKSPIPKWMQRLMICKNRYFS 1156
            L+  YE SVRPV NSSKPV   MGITLTQIFDMDEKNQVLV+NVWLDQQW DE+L W+  EF + +K+R+PS KIWKPD+VLYNNAADFAD +MPALAM+ ++G VFWP+PTKL+SSCK+DVTYFPFD Q+C LKFGSWTYDG+QV+L  LK  VD+  YVENGEW+L  TK      RN + Y CCPEPY DVTF L+L RR+LY++YHVIYPCIMMSTLTLLVFCLPPDSGEKIALGITVLLAFSVLMLSIA++LPETSESVPLISIYLT VMSMTSVSVIMTVFVLNLHHRGP++SP+P W++RL++ + R+ S
Sbjct:    4 LLHGYELSVRPVFNSSKPVTTLMGITLTQIFDMDEKNQVLVSNVWLDQQWKDEFLTWDPEEFSNQAKIRLPSSKIWKPDLVLYNNAADFADSLMPALAMIDSNGTVFWPIPTKLRSSCKVDVTYFPFDEQVCNLKFGSWTYDGYQVDLHLLKSDVDVSSYVENGEWELLGTKASDLRKRNVVRYPCCPEPYPDVTFYLFLRRRLLYYMYHVIYPCIMMSTLTLLVFCLPPDSGEKIALGITVLLAFSVLMLSIADRLPETSESVPLISIYLTVVMSMTSVSVIMTVFVLNLHHRGPSRSPVPNWLRRLLL-QQRFGS 319          
BLAST of Neuronal acetylcholine receptor subunit alpha-10 vs. TrEMBL
Match: A0A1I8H6J3 (Uncharacterized protein OS=Macrostomum lignano OX=282301 PE=3 SV=1)

HSP 1 Score: 474.552 bits (1220), Expect = 1.400e-158
Identity = 226/312 (72.44%), Postives = 263/312 (84.29%), Query Frame = 2
Query:  221 LMKDYEPSVRPVRNSSKPVIAKMGITLTQIFDMDEKNQVLVTNVWLDQQWYDEYLQWNTSEFPSISKLRIPSEKIWKPDIVLYNNAADFADKMMPALAMVKNDGEVFWPVPTKLKSSCKIDVTYFPFDSQICTLKFGSWTYDGFQVELDKLKGVDLDMYVENGEWKLKKTKVLRNNIVYTCCPEPYYDVTFVLYLERRILYFIYHVIYPCIMMSTLTLLVFCLPPDSGEKIALGITVLLAFSVLMLSIAEKLPETSESVPLISIYLTTVMSMTSVSVIMTVFVLNLHHRGPNKSPIPKWMQRLMICKNRYFS 1156
            L+  YE SVRPV NSSKPV   MGITLTQIFDMDEKNQVLV+NVWLDQQW DE+L W+  EF + +K+R+PS KIWKPD+VLYNNAADFAD +MPALAM+ ++G VFWP+PTKL+SSCK+DVTYFPFD Q+C LKFGSWTYDG+QV+L  LK  D+D               +RN + Y CCPEPY DVTF L+L RR+LY++YHVIYPCIMMSTLTLLVFCLPPDSGEKIALGITVLLAFSVLMLSIA++LPETSESVPLISIYLT VMSMTSVSVIMTVFVLNLHHRGP++SP+P W++RL++ + R+ S
Sbjct:    4 LLHGYELSVRPVFNSSKPVTTLMGITLTQIFDMDEKNQVLVSNVWLDQQWKDEFLTWDPEEFSNQAKIRLPSSKIWKPDLVLYNNAADFADSLMPALAMIDSNGIVFWPIPTKLRSSCKVDVTYFPFDEQVCNLKFGSWTYDGYQVDLHLLKS-DVD--------------TIRNVVRYPCCPEPYPDVTFYLFLRRRLLYYMYHVIYPCIMMSTLTLLVFCLPPDSGEKIALGITVLLAFSVLMLSIADRLPETSESVPLISIYLTVVMSMTSVSVIMTVFVLNLHHRGPSRSPVPNWLRRLLL-QQRFGS 299          

HSP 2 Score: 83.9593 bits (206), Expect = 2.929e-13
Identity = 42/76 (55.26%), Postives = 57/76 (75.00%), Query Frame = 2
Query: 1592 NDQQEINTKILSALNRILVKHEIDESNYNLIQEWREVAQFVDRILFWLYLFXXXXXXIIVLIIAPVFGIIPINIVD 1819
            N + E+N  IL AL +I+ KH+ D+S   +I EWR VAQFVD++LFW+YL  TS STII+L+IAPV+ IIP + +D
Sbjct:  413 NQRAEVNGDILEALRKIIDKHDADDSESRVIAEWRAVAQFVDKLLFWVYLLCTSASTIIILVIAPVYRIIPHSQMD 488          
BLAST of Neuronal acetylcholine receptor subunit alpha-10 vs. TrEMBL
Match: R7V7D5 (Uncharacterized protein OS=Capitella teleta OX=283909 GN=CAPTEDRAFT_204309 PE=3 SV=1)

HSP 1 Score: 474.552 bits (1220), Expect = 4.929e-157
Identity = 258/544 (47.43%), Postives = 346/544 (63.60%), Query Frame = 2
Query:  179 NDENLPEEHRLFKKLMKDYEPSVRPVRNSSKPVIAKMGITLTQIFDMDEKNQVLVTNVWLDQQWYDEYLQWNTSEFPSISKLRIPSEKIWKPDIVLYNNAADFADKMMPALAMVKNDGEVFWPVPTKLKSSCKIDVTYFPFDSQICTLKFGSWTYDGFQVEL-DKLKGVDLDMYVENGEWKLKKTKVLRNNIVYTCCPEPYYDVTFVLYLERRILYFIYHVIYPCIMMSTLTLLVFCLPPDSGEKIALGITVLLAFSVLMLSIAEKLPETSESVPLISIYLTTVMSMTSVSVIMTVFVLNLHHRGPNKSPIPKWMQRLMICKNRYFSCKGSLTKNRKIPFKGIKNIESLLMSINSKLKQ-FPVKKSKSFPSPQNH--VENYLNKYPNEVGLGNIKLNSYPTMETDVLSGSVTANHEYEP---MFISDNDYRCTGNIIHXXXXXXXXXXXXXXXXNILINPSSPTVDKAVSTDAYPSCDNDQQEINTKILSALNRILVKHEIDESNYNLIQEWREVAQFVDRILFWLYLFXXXXXXIIVLIIAPV 1789
            ++  LP E RL  KL++ YE +VRPV+N+S  V+ KMG+TLTQIFD+DEKN+VLVTNVWLDQ+W D +L WN  +F  +  LR+P  K+W PDIVLYNNAA++ D M PA AM+ ++G VFWPVPTKL SSCK+DVTYFPFD Q C LKFGSWTYDGFQV++ ++   +DL  Y+ NGEW+L    + RN + Y CC EP+ DVTF +++ RR +Y++Y+VI+PC+MMSTLT+LVFCLPPDSGEKI +GITVLLAFSV +L + E LPETSE +PL+SIYLT VM MTSVSVIMTVFVLNLHHRGPN +P+P W+ ++ + +                    +K+  +++   NS     FP   S+S  S +NH  +EN   +  +E       L++    E D      + N +YE     F S  D+                               S T+D+       P+C   Q      IL AL +I+ ++E +++  + + EWR++A  VDRILFW++L  T +STIIVLIIAP+
Sbjct:  148 SEAALPIEQRLMNKLLRRYERAVRPVKNASDTVVVKMGMTLTQIFDLDEKNEVLVTNVWLDQEWDDMFLSWNPEDFGGLEVLRLPCHKLWLPDIVLYNNAAEYTDGMFPANAMITHEGGVFWPVPTKLLSSCKVDVTYFPFDDQKCRLKFGSWTYDGFQVDMTNRTVDIDLSNYIANGEWELISIVIERNVVYYACCAEPFPDVTFTIHIRRRTVYYLYNVIFPCVMMSTLTVLVFCLPPDSGEKITMGITVLLAFSVFLLRMGEDLPETSEFIPLLSIYLTIVMGMTSVSVIMTVFVLNLHHRGPNNTPVPPWLHKVFLSR--------------------LKDTHNVVFKQNSLYDDFFPSGTSQSRFS-RNHLTIENLAQELKHE-------LDTQYAREHD-----SSPNDKYESDTTQFESSPDH-------------------------------SSTLDQQ------PACSTTQH-----ILRALYKIVHRYEREDNEEHRVYEWRQLAVIVDRILFWIFLTGTLSSTIIVLIIAPL 616          
BLAST of Neuronal acetylcholine receptor subunit alpha-10 vs. Ensembl Cavefish
Match: chrna7 (neuronal acetylcholine receptor subunit alpha-7-like [Source:NCBI gene;Acc:103030483])

HSP 1 Score: 317.775 bits (813), Expect = 4.061e-101
Identity = 155/343 (45.19%), Postives = 216/343 (62.97%), Query Frame = 2
Query:  107 NIYGLILILIVNRNTEGKSLSEVKNDENLPEEHRLFKKLMKDYEPSVRPVRNSSKPVIAKMGITLTQIFDMDEKNQVLVTNVWLDQQWYDEYLQWNTSEFPSISKLRIPSEKIWKPDIVLYNNAADFADKMMPALAMVKNDGEVFWPVPTKLKSSCKIDVTYFPFDSQICTLKFGSWTYDGFQVELDKLKGVDLDMYVENGEWKLKKTKVLRNNIVYTCCPEPYYDVTFVLYLERRILYFIYHVIYPCIMMSTLTLLVFCLPPDSGEKIALGITVLLAFSVLMLSIAEKLPETSESVPLISIYLTTVMSMTSVSVIMTVFVLNLHHRGPNKSPIPKWMQRLMI 1135
             +YG+ L L V       SL           + RL++ LMK+Y P  RPV N S+ +      +L QI D+DEKNQVL +N+WL   WYD YL+WN S++P ++ +R P  +IWKPDI+LYN+A +  D       +V  DG   +  P   KS+C IDV +FPFD Q C LKFGSWTY G+ ++L  ++  D+  Y+ NGEW L + +  RN   Y CC EPY DVTF + + RR LY+  +++ PC+++STL LLVF LP DSGEKI+LGITVLL+ +V ML +AE +P TS+SVPLI+ Y  T M +  +SVI TV+VL  H+  P+   +P W + +++
Sbjct:    2 GLYGVFLCLAVTICLWRVSLQG-------EHQRRLYQDLMKNYNPLERPVFNDSQSLTVNFSFSLMQIMDVDEKNQVLTSNIWLQLYWYDHYLKWNLSDYPGVTNVRFPDNQIWKPDILLYNSADERFDATFHTNVVVSADGSCHYLPPGIFKSTCYIDVKWFPFDVQRCALKFGSWTYGGWSLDLQMMEA-DISGYIANGEWDLVEVQGQRNEKFYDCCREPYPDVTFTVVMRRRTLYYGLNLLIPCVLISTLALLVFLLPADSGEKISLGITVLLSLTVFMLLVAEIMPATSDSVPLIAQYFATTMVIVGLSVIATVWVLQYHYHDPDGGKMPTWTRIVLL 336          
BLAST of Neuronal acetylcholine receptor subunit alpha-10 vs. Ensembl Cavefish
Match: chrna7 (neuronal acetylcholine receptor subunit alpha-7-like [Source:NCBI gene;Acc:103030483])

HSP 1 Score: 314.309 bits (804), Expect = 7.235e-100
Identity = 152/318 (47.80%), Postives = 209/318 (65.72%), Query Frame = 2
Query:  188 NLPEEH--RLFKKLMKDYEPSVRPVRNSSKPVIAKMGITLTQIFDMDEKNQVLVTNVWLDQQWYDEYLQWNTSEFPSISKLRIPSEKIWKPDIVLYNNAADFADKMMPALAMVKNDGEVFWPVPTKLKSSCKIDVTYFPFDSQICTLKFGSWTYDGFQVELDKLKGVDLDMYVENGEWKLKKTKVLRNNIVYTCCPEPYYDVTFVLYLERRILYFIYHVIYPCIMMSTLTLLVFCLPPDSGEKIALGITVLLAFSVLMLSIAEKLPETSESVPLISIYLTTVMSMTSVSVIMTVFVLNLHHRGPNKSPIPKWMQRLMI 1135
            +L  EH  RL++ LMK+Y P  RPV N S+ +      +L QI D+DEKNQVL +N+WL   WYD YL+WN S++P ++ +R P  +IWKPDI+LYN+A +  D       +V  DG   +  P   KS+C IDV +FPFD Q C LKFGSWTY G+ ++L  ++  D+  Y+ NGEW L   K  RN   Y CC EPY DVTF + + RR LY+  +++ PC+++STL LLVF LP DSGEKI+LGITVLL+ +V ML +AE +P TS+SVPLI+ Y  T M +  +SVI TV+VL  H+  P+   +P W + +++
Sbjct:    7 SLQGEHQRRLYQDLMKNYNPLERPVFNDSQSLTVNFSFSLMQIMDVDEKNQVLTSNIWLQLYWYDHYLKWNLSDYPGVTNVRFPDNQIWKPDILLYNSADERFDATFHTNVVVSADGSCHYLPPGIFKSTCYIDVKWFPFDVQRCALKFGSWTYGGWSLDLQMMEA-DISGYIANGEWDLVG-KGQRNEKFYDCCREPYPDVTFTVVMRRRTLYYGLNLLIPCVLISTLALLVFLLPADSGEKISLGITVLLSLTVFMLLVAEIMPATSDSVPLIAQYFATTMVIVGLSVIATVWVLQYHYHDPDGGKMPTWTRIVLL 322          
BLAST of Neuronal acetylcholine receptor subunit alpha-10 vs. Ensembl Cavefish
Match: ENSAMXT00000019858.2 (neuronal acetylcholine receptor subunit alpha-10 [Source:NCBI gene;Acc:103033580])

HSP 1 Score: 310.071 bits (793), Expect = 8.631e-99
Identity = 141/312 (45.19%), Postives = 210/312 (67.31%), Query Frame = 2
Query:  203 HRLFKKLMKDYEPSVRPVRNSSKPVIAKMGITLTQIFDMDEKNQVLVTNVWLDQQWYDEYLQWNTSEFPSISKLRIPSEKIWKPDIVLYNNAADFADKMMPALAMVKNDGEVFWPVPTKLKSSCKIDVTYFPFDSQICTLKFGSWTYDGFQVE-LDKLKGVDLDMYVENGEWKLKKTKVLRNNIVYTCCPEPYYDVTFVLYLERRILYFIYHVIYPCIMMSTLTLLVFCLPPDSGEKIALGITVLLAFSVLMLSIAEKLPETSESVPLISIYLTTVMSMTSVSVIMTVFVLNLHHRGPNKSPIPKWMQRLMI 1135
            H+L K L  +Y  +VRPV ++   +   + ITL+QI DMDE+NQ+L T +W+ Q W D YL WN +++  +  +RIPS  +W+PDIVLYNNA D     M    ++ +DG++ W  P   KSSCK+DV++FPFDSQ C L FGSWT++G Q++ L+ +   DL  +VEN EW++      +N I+Y CC EPY D+T+ L L+RR  ++I++++ PC+M+S L  L F LP DSGEK++LG+TVLLA +V  L +AE +P  SE+VPLI  Y    M+M + S  +T+F++N+HH G +  P+P+W +R ++
Sbjct:   21 HKLLKDLFVNYSNAVRPVEDTDNIINVTLQITLSQIIDMDERNQILTTYLWIRQVWLDAYLTWNKADYDGLDTIRIPSSYVWRPDIVLYNNADDQFSSSMETNVVIHHDGQIMWDQPAISKSSCKVDVSFFPFDSQKCRLTFGSWTHNGNQMDILNGMDSADLADFVENVEWEVLGMPAKKNVILYGCCSEPYPDITYTLQLKRRASFYIFNLLIPCMMISFLAPLGFYLPADSGEKVSLGVTVLLALTVFQLLVAESMPP-SENVPLIGKYYIATMTMITASTALTIFIMNIHHCGSDAQPVPEWARRFIL 331          
BLAST of Neuronal acetylcholine receptor subunit alpha-10 vs. Ensembl Cavefish
Match: chrna7 (neuronal acetylcholine receptor subunit alpha-7-like [Source:NCBI gene;Acc:103030483])

HSP 1 Score: 308.916 bits (790), Expect = 3.785e-98
Identity = 145/304 (47.70%), Postives = 201/304 (66.12%), Query Frame = 2
Query:  224 MKDYEPSVRPVRNSSKPVIAKMGITLTQIFDMDEKNQVLVTNVWLDQQWYDEYLQWNTSEFPSISKLRIPSEKIWKPDIVLYNNAADFADKMMPALAMVKNDGEVFWPVPTKLKSSCKIDVTYFPFDSQICTLKFGSWTYDGFQVELDKLKGVDLDMYVENGEWKLKKTKVLRNNIVYTCCPEPYYDVTFVLYLERRILYFIYHVIYPCIMMSTLTLLVFCLPPDSGEKIALGITVLLAFSVLMLSIAEKLPETSESVPLISIYLTTVMSMTSVSVIMTVFVLNLHHRGPNKSPIPKWMQRLMI 1135
            MK+Y P  RPV N S+ +      +L QI D+DEKNQVL +N+WL   WYD YL+WN S++P ++ +R P  +IWKPDI+LYN+A +  D       +V  DG   +  P   KS+C IDV +FPFD Q C LKFGSWTY G+ ++L  ++  D+  Y+ NGEW L + +  RN   Y CC EPY DVTF + + RR LY+  +++ PC+++STL LLVF LP DSGEKI+LGITVLL+ +V ML +AE +P TS+SVPLI+ Y  T M +  +SVI TV+VL  H+  P+   +P W + +++
Sbjct:    1 MKNYNPLERPVFNDSQSLTVNFSFSLMQIMDVDEKNQVLTSNIWLQLYWYDHYLKWNLSDYPGVTNVRFPDNQIWKPDILLYNSADERFDATFHTNVVVSADGSCHYLPPGIFKSTCYIDVKWFPFDVQRCALKFGSWTYGGWSLDLQMMEA-DISGYIANGEWDLVEVQGQRNEKFYDCCREPYPDVTFTVVMRRRTLYYGLNLLIPCVLISTLALLVFLLPADSGEKISLGITVLLSLTVFMLLVAEIMPATSDSVPLIAQYFATTMVIVGLSVIATVWVLQYHYHDPDGGKMPTWTRIVLL 303          
BLAST of Neuronal acetylcholine receptor subunit alpha-10 vs. Ensembl Cavefish
Match: ENSAMXT00000032409.1 (neuronal acetylcholine receptor subunit alpha-10 [Source:NCBI gene;Acc:103033580])

HSP 1 Score: 310.842 bits (795), Expect = 5.568e-98
Identity = 141/312 (45.19%), Postives = 210/312 (67.31%), Query Frame = 2
Query:  203 HRLFKKLMKDYEPSVRPVRNSSKPVIAKMGITLTQIFDMDEKNQVLVTNVWLDQQWYDEYLQWNTSEFPSISKLRIPSEKIWKPDIVLYNNAADFADKMMPALAMVKNDGEVFWPVPTKLKSSCKIDVTYFPFDSQICTLKFGSWTYDGFQVE-LDKLKGVDLDMYVENGEWKLKKTKVLRNNIVYTCCPEPYYDVTFVLYLERRILYFIYHVIYPCIMMSTLTLLVFCLPPDSGEKIALGITVLLAFSVLMLSIAEKLPETSESVPLISIYLTTVMSMTSVSVIMTVFVLNLHHRGPNKSPIPKWMQRLMI 1135
            H+L K L  +Y  +VRPV ++   +   + ITL+QI DMDE+NQ+L T +W+ Q W D YL WN +++  +  +RIPS  +W+PDIVLYNNA D     M    ++ +DG++ W  P   KSSCK+DV++FPFDSQ C L FGSWT++G Q++ L+ +   DL  +VEN EW++      +N I+Y CC EPY D+T+ L L+RR  ++I++++ PC+M+S L  L F LP DSGEK++LG+TVLLA +V  L +AE +P  SE+VPLI  Y    M+M + S  +T+F++N+HH G +  P+P+W +R ++
Sbjct:   31 HKLLKDLFVNYSNAVRPVEDTDNIINVTLQITLSQIIDMDERNQILTTYLWIRQVWLDAYLTWNKADYDGLDTIRIPSSYVWRPDIVLYNNADDQFSSSMETNVVIHHDGQIMWDQPAISKSSCKVDVSFFPFDSQKCRLTFGSWTHNGNQMDILNGMDSADLADFVENVEWEVLGMPAKKNVILYGCCSEPYPDITYTLQLKRRASFYIFNLLIPCMMISFLAPLGFYLPADSGEKVSLGVTVLLALTVFQLLVAESMPP-SENVPLIGKYYIATMTMITASTALTIFIMNIHHCGSDAQPVPEWARRFIL 341          
BLAST of Neuronal acetylcholine receptor subunit alpha-10 vs. Ensembl Sea Lamprey
Match: chrna3 (cholinergic receptor, nicotinic, alpha 3 [Source:ZFIN;Acc:ZDB-GENE-070822-1])

HSP 1 Score: 291.582 bits (745), Expect = 6.444e-92
Identity = 141/313 (45.05%), Postives = 207/313 (66.13%), Query Frame = 2
Query:  206 RLFKKLMKDYEPSVRPVRNSSKPVIAKMGITLTQIFDMDEKNQVLVTNVWLDQQWYDEYLQWNTSEFPSISKLRIPSEKIWKPDIVLYNNA-ADFADKMMPALAMVKNDGEVFWPVPTKLKSSCKIDVTYFPFDSQICTLKFGSWTYDGFQVELDKLKGVDLDM--YVENGEWKLKKTKVLRNNIVYTCCPEPYYDVTFVLYLERRILYFIYHVIYPCIMMSTLTLLVFCLPPDSGEKIALGITVLLAFSVLMLSIAEKLPETSESVPLISIYLTTVMSMTSVSVIMTVFVLNLHHRGPNKSPIPKWMQRLMI 1135
            RL+K L   Y P +RPV N S PVI +  ++++Q+  +DE NQ++ TN+WL   W D   QWN  +F  +  +R+PS+KIWKPDIVLYNNA  DF  +     A++K DG V W  P   KSSCKIDVTYFPFD Q CT+KFGSWTYD  +++L  L G  +++  + E+GEW +      +++I Y CC + Y D+T+ +Y+ R  L++  ++I PC+++S LT+LVF LP D GEK+ L I+VLL+ +V +L I E +P TS  +PLI  YL   M   ++S+++T+FVLN+H+R P    +P W++R+ +
Sbjct:   10 RLYKTLFTSYNPYIRPVFNVSDPVIVRFEVSMSQLVKLDEVNQIMATNLWLKHTWNDYKFQWNPGQFEGMEYIRVPSDKIWKPDIVLYNNADGDFQVEGKTK-ALLKYDGTVMWMPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWTYDKAKIDL-VLVGTKINLKDFWESGEWVIIDVPGYKHDIKYNCCEQIYPDITYSVYVRRLPLFYTINLIIPCLLISFLTVLVFYLPSDCGEKVTLSISVLLSLTVFLLVITETIPSTSLVIPLIGEYLLFTMIFVTLSIVITIFVLNVHYRTPEAHTMPNWVRRVFL 320          
BLAST of Neuronal acetylcholine receptor subunit alpha-10 vs. Ensembl Sea Lamprey
Match: chrnb3b (cholinergic receptor, nicotinic, beta 3b (neuronal) [Source:ZFIN;Acc:ZDB-GENE-030102-4])

HSP 1 Score: 264.233 bits (674), Expect = 7.389e-82
Identity = 135/316 (42.72%), Postives = 198/316 (62.66%), Query Frame = 2
Query:  200 EHRLFKKLMKDYEPSVRPVRNSSKPVIAKMGITLTQIFDMDEKNQVLVTNVWLDQQWYDEYLQWNTSEFPSISKLRIPSEKIWKPDIVLYNNAADFADKMMPALAMVKNDGEVFWPVPTKLKSSCKIDVTYFPFDSQICTLKFGSWTYDGFQVELDKLKG-VDLDMYVENGEWKLKKTKVLRNNIVYTCCPEPYYDVTFVLYLERRILYFIYHVIYPCIMMSTLTLLVFCLPPDSGEKIALGITVLLAFSVLMLSIAEKLPETSESVPLISIYLTTVMSMTSVSVIMTVFVLNLHHRGPN-KSPIPKWMQRLMICK 1141
            E RL K+++KDY+  VRPV   S  V  K G+ + Q+ D+DEKNQ++ TNVWL Q+W D  L+WN  ++  I+ +R+P+  IW PDIVLY+NA    +  +   A+VK+DG + W  P   KSSC IDVT+FPFD Q C++KFGSWTYDG  V+L  +   VD   Y +NGEW+        N  V       Y  +T+   + R  L++   +I PC+ +S LT+ VF LP D GEKI+L  +VL++ +V +L I E +P +S+ +PLI  YL  +M   ++S+I+TVFV+N+HHR  +   P+  W+++L + K
Sbjct:   35 EDRLLKRMLKDYQKWVRPVDKLSDTVEVKFGLGIAQLVDVDEKNQLMTTNVWLKQEWVDINLRWNPDDYGGINSIRVPASSIWLPDIVLYDNADGRFEGSIVTKAVVKHDGRIKWTPPAIYKSSCTIDVTFFPFDQQNCSMKFGSWTYDGTLVDLIMVNSDVDRGEYFDNGEWEFLNAT--GNKGVRLDGHRFYPYITYSFVIRRLPLFYTLFLIVPCLGLSFLTVFVFYLPSDEGEKISLCTSVLVSLTVFLLVIEEIIPSSSKVIPLIGEYLLFIMIFVTLSIIITVFVINVHHRSSSTHHPMAPWVRQLFLHK 348          
BLAST of Neuronal acetylcholine receptor subunit alpha-10 vs. Ensembl Sea Lamprey
Match: chrna2a (cholinergic receptor, nicotinic, alpha 2a (neuronal) [Source:ZFIN;Acc:ZDB-GENE-040108-2])

HSP 1 Score: 257.684 bits (657), Expect = 3.725e-78
Identity = 133/280 (47.50%), Postives = 186/280 (66.43%), Query Frame = 2
Query:  302 TQIFDMDEKNQVLVTNVWLDQQWYDEYLQWNTSEFPSISKLRIPSEKIWKPDIVLYNNA-ADFADKMMPALAMVKNDGEVFWPVPTKLKSSCKIDVTYFPFDSQICTLKFGSWTYDGFQVELDKL-KGVDLDMYVENGEWKLKKTKVLRNNIVYTCCPEPYYDVTFVLYLERRILYFIYHVIYPCIMMSTLTLLVFCLPPDSGEKIALGITVLLAFSVLMLSIAEKLPETSESVPLISIYLTTVMSMTSVSVIMTVFVLNLHHRGPNKSPIPKWMQRLMI 1135
            T + D DEKNQ++ TNVWL Q+W D  LQW+ +E+ +++ +R+PSE IW PDIVLYNNA  DFA   M   A + + G V W  P   KSSC IDVT+FPFD Q CT+KFGSWTYD  +++L  + + VDL  Y E+GEW +       N   Y CCP+ Y D+T+   + R  L++  ++I PC+++S LT+LVF LP D GEKI L I+VLL+ +V +L I E +P TS  +PLI  YL   M   ++S+++TVFVLN+HHR P    +P+W++R+ +
Sbjct:    8 THLCDCDEKNQMMTTNVWLKQEWDDYKLQWDPAEYENVTSIRVPSELIWVPDIVLYNNADGDFAVTHM-TKAHLFHTGRVRWKPPAIYKSSCSIDVTFFPFDQQNCTMKFGSWTYDKAKIDLVSMARDVDLKDYWESGEWAIVHAVGTYNTKKYDCCPQVYPDITYSFIIRRLPLFYTINLIIPCLLISCLTVLVFYLPSDCGEKITLCISVLLSLTVFLLLITEIIPSTSLVIPLIGEYLLFTMIFVTLSIVITVFVLNVHHRSPATHAMPRWVRRVFL 286          
BLAST of Neuronal acetylcholine receptor subunit alpha-10 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000008550.1 (pep scaffold:Pmarinus_7.0:GL476601:34:38373:1 gene:ENSPMAG00000007717.1 transcript:ENSPMAT00000008550.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 234.572 bits (597), Expect = 5.238e-71
Identity = 113/245 (46.12%), Postives = 158/245 (64.49%), Query Frame = 2
Query:  401 EFPSISKLRIPSEKIWKPDIVLYNNAADFADKMMPALAMVKNDGEVFWPVPTKLKSSCKIDVTYFPFDSQICTLKFGSWTYDGFQVELDKLKGVDLDMYVENGEWKLKKTKVLRNNIVYTCCPEPYYDVTFVLYLERRILYFIYHVIYPCIMMSTLTLLVFCLPPDSGEKIALGITVLLAFSVLMLSIAEKLPETSESVPLISIYLTTVMSMTSVSVIMTVFVLNLHHRGPNKSPIPKWMQRLMI 1135
            E P +  LR    +IW PDI+LYN+A +  D       +V   G      P  LKS+C IDV +FPFD Q C LKFGSWT+DG+ ++L  L+  D   Y+ NGEW L +    RN + Y CC EPY DVT+ L + RR LY+  +++ PC+++S L+LLVF LP DSGEKI+LGITVLL+ +V ML +AE +P TS+SVPLI  Y  + M + + SV++TV VL  HH  P+   +P+W++ +++
Sbjct:    2 EHPGVKNLRFQPHQIWTPDILLYNSADERFDATFHTNVLVNYTGNCQHLPPGMLKSTCYIDVRWFPFDVQKCDLKFGSWTHDGWLIDLQMLEA-DTSGYIANGEWDLVEIPGKRNELYYDCCQEPYPDVTYTLTIRRRTLYYGLNLLVPCVLISALSLLVFLLPADSGEKISLGITVLLSLTVFMLLVAEIMPATSDSVPLIGQYFASTMIIVAFSVVVTVIVLQYHHHNPDGKKMPQWVRVILL 245          
BLAST of Neuronal acetylcholine receptor subunit alpha-10 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000000149.1 (pep scaffold:Pmarinus_7.0:GL480219:31373:46583:1 gene:ENSPMAG00000000129.1 transcript:ENSPMAT00000000149.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 211.846 bits (538), Expect = 3.484e-62
Identity = 101/207 (48.79%), Postives = 138/207 (66.67%), Query Frame = 2
Query:  515 MVKNDGEVFWPVPTKLKSSCKIDVTYFPFDSQICTLKFGSWTYDGFQVELDKLKGVDLDMYVENGEWKLKKTKVLRNNIVYTCCPEPYYDVTFVLYLERRILYFIYHVIYPCIMMSTLTLLVFCLPPDSGEKIALGITVLLAFSVLMLSIAEKLPETSESVPLISIYLTTVMSMTSVSVIMTVFVLNLHHRGPNKSPIPKWMQRLMI 1135
            +V + G   +  P  LKSSCKIDV +FPFD Q C LKFGSWT+DG+ ++L  L   D   Y+ NGEW L      RN + Y CC EPY DVT+ L L RR LY+  +++ PC+++S L LLVF LP +SGEKI+LGITVLL+ +V ML +AE +P TS+SVPLI  Y  + + +   SV++TV VL  HH  P+ + +P W++ L++
Sbjct:   15 LVNHTGGCQYIPPGILKSSCKIDVRWFPFDVQSCDLKFGSWTHDGWLIDLHLLH-ADTSGYLPNGEWDLIGVVGKRNELFYECCQEPYTDVTYTLLLRRRTLYYALNLLLPCMLISALALLVFLLPAESGEKISLGITVLLSLTVFMLLVAEIMPATSDSVPLIGQYFASTLMIVGFSVVVTVLVLQCHHHDPDGTNMPTWVRVLLV 220          
BLAST of Neuronal acetylcholine receptor subunit alpha-10 vs. Ensembl Nematostella
Match: EDO42054 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S2J7])

HSP 1 Score: 282.722 bits (722), Expect = 1.456e-88
Identity = 132/316 (41.77%), Postives = 199/316 (62.97%), Query Frame = 2
Query:  200 EHRLFKKLMKDYEPSVRPVRNSSKPVIAKMGITLTQIFDMDEKNQVLVTNVWLDQQWYDEYLQWNTSEFPSISKLRIPSEKIWKPDIVLYNNAAD-FADKM--MPALAMVKNDGEVFWPVPTKLKSSCKIDVTYFPFDSQICTLKFGSWTYDGFQVELDKLK-GVDLDMYVENGEWKLKKTKVLRNNIVYTCCPEPYYDVTFVLYLERRILYFIYHVIYPCIMMSTLTLLVFCLPPDSGEKIALGITVLLAFSVLMLSIAEKLPETSESVPLISIYLTTVMSMTSVSVIMTVFVLNLHHRGPNKSPIPKWMQRLMI 1135
            E RL   L ++Y+  VRPV N S  V  +  ++L QI  ++ K+Q++  +VW+ Q+W +  L WNTS++  I  + +   K+W PDI+LYNNA + +A  +       +  +DG   W  P    S+C I+V YFPFDSQ C+LKFGSWTY G ++ +       DL  YV NGEW L       N + Y CC  P+YDVT  L ++R+ LY+++++I PC +++TLTL+ F LPP+SGEK+ LGITVLLA +V +L +AE LP TS+ +PL+  Y    M +T++S++ T  +LN  HR P+ SP+P W++ +++
Sbjct:   38 EKRLLADLFRNYDSEVRPVFNDSDKVNVEFSLSLIQIIAVNSKSQLVTVSVWIRQKWTNPMLAWNTSKYGGIESVNLNPAKVWIPDIILYNNADETYAGGLEKYKTSVIASSDGTQEWNSPASFTSTCNINVRYFPFDSQNCSLKFGSWTYVGNRLTMTSTSDSADLSKYVNNGEWHLLAMPAKLNRVFYNCCKYPFYDVTLYLEIQRKPLYYVFNLIIPCALIATLTLIKFFLPPESGEKVGLGITVLLAMTVFLLLVAETLPSTSDHIPLLGQYFVATMFVTAISLVATCLILNFFHRNPSTSPMPHWVKVIIL 353          
BLAST of Neuronal acetylcholine receptor subunit alpha-10 vs. Ensembl Nematostella
Match: EDO43642 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RY59])

HSP 1 Score: 267.314 bits (682), Expect = 6.357e-85
Identity = 125/287 (43.55%), Postives = 185/287 (64.46%), Query Frame = 2
Query:  200 EHRLFKKLMKDYEPSVRPVRNSSKPVIAKMGITLTQIFDMDEKNQVLVTNVWLDQQWYDEYLQWNTSEFPSISKLRIPSEKIWKPDIVLYNNAADFADKMMPAL---AMVKNDGEVFWPVPTKLKSSCKIDVTYFPFDSQICTLKFGSWTYDGFQVELDKLKGVDL--DMYVENGEWKLKKTKVLRNNIVYTCCPEPYYDVTFVLYLERRILYFIYHVIYPCIMMSTLTLLVFCLPPDSGEKIALGITVLLAFSVLMLSIAEKLPETSESVPLISIYLTTVMSMTSV 1045
            E++L K L  +Y PSVRPV  ++  V  ++G++L QI D+DE+NQ+L++N+W+ Q+W +  L W+ + F +++ + +   ++W+PD++LYNNA    D  +        +K DG   W  P   KS+CK DV YFPFD Q C LKFGSWTYDG ++ +    G D+  D +V NGEW+L      RN + Y CC EPY DVTF L + R  L++  +++ PC +++ LTLL + LPP+SGE+I L +T LLA +V +L ++E +P  +E VPLISIY TT M M +V
Sbjct:    2 ENKLLKDLFSNYNPSVRPVLKATSSVTVQLGVSLHQIIDLDERNQILISNLWVRQKWNNPLLTWDPTHFGNLTSINVDPLRVWRPDLILYNNADRDTDGALDRFYTKVQLKFDGSSLWLAPIIFKSTCKFDVAYFPFDEQSCILKFGSWTYDGLRLNIVPENGTDIGIDKFVSNGEWELTGVSANRNVMFYDCCVEPYPDVTFTLKIRRLTLFYYMNMLIPCFLITGLTLLSYILPPESGERITLVVTSLLAQAVYLLLVSEIMPPVAEVVPLISIYYTTAMFMVTV 288          
BLAST of Neuronal acetylcholine receptor subunit alpha-10 vs. Ensembl Nematostella
Match: EDO45564 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RSH5])

HSP 1 Score: 265.003 bits (676), Expect = 1.629e-83
Identity = 127/315 (40.32%), Postives = 196/315 (62.22%), Query Frame = 2
Query:  200 EHRLFKKLMKDYEPSVRPVRNSSKPVIAKMGITLTQIFDMDEKNQVLVTNVWLDQQWYDEYLQWNTSEFPSISKLRIPSEKIWKPDIVLYNNAADFADKMMPAL---AMVKNDGEVFWPVPTKLKSSCKIDVTYFPFDSQICTLKFGSWTYDGFQVELDKLKG-VDLDMYVENGEWKLKKTKVLRNNIVYTCCPEPYYDVTFVLYLERRILYFIYHVIYPCIMMSTLTLLVFCLPPDSGEKIALGITVLLAFSVLMLSIAEKLPETSESVPLISIYLTTVMSMTSVSVIMTVFVLNLHHRGPNKSPIPKWMQRLM 1132
            EH+L   L KDY+   RPV N S+ V   + I  +Q+ D+D KNQ+L + VW+ Q W + +L WN  ++  +  + + S  +WKPDI+LYNN        M       ++ +DG   W  PT++KS C+ID+TYFPFD+Q C + FGSWTY G  + L   +   DL  Y  +GEW+LK   V+RN + Y+CC  PY DVT+ + + R++L+++ ++I PC++++ LT+  F LPP SGE+I+L IT+LL  +V ML   E +P TSE +PLI+ Y   VM   +VS+++T  V+ ++H+    SP+P  M+ ++
Sbjct:    2 EHKLITTLFKDYQRDARPVYNKSEAVRVSLDIAYSQLIDLDGKNQILSSKVWIRQVWRNPFLSWNPDDYGGLESINVNSNLVWKPDIILYNNIGIGQTGAMYNFDTKVVIDSDGTNSWYAPTEIKSICQIDITYFPFDAQSCPIIFGSWTYTGNYLNLVNARNQSDLSKYTISGEWELKSAPVVRNVVKYSCCKHPYIDVTYTINIRRKVLFYLNNLILPCMVLAILTVCSFLLPPASGERISLVITILLGLTVFMLVFTESVPRTSEVIPLIAKYSFAVMCEVAVSLLLTCVVMRIYHK---NSPMPLPMRYIV 313          
BLAST of Neuronal acetylcholine receptor subunit alpha-10 vs. Ensembl Nematostella
Match: EDO42038 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S2N9])

HSP 1 Score: 267.314 bits (682), Expect = 9.414e-82
Identity = 131/335 (39.10%), Postives = 205/335 (61.19%), Query Frame = 2
Query:  197 EEHRLFKKLMKDYEPSVRPVRNSSKPVIAKMGITLTQIFDMDEKNQVLVTNVWLDQQWYDEYLQWNTSEFPSISKLRIPSEKIWKPDIVLYNNAADFADKMMPALA---MVKNDGEVFWPVPTKLKSSCKIDVTYFPFDSQICTLKFGSWTYDGFQVELD-KLKGVDLDMYVENGEWKLKKTKVLRNNIVYTCCPEPYYDVTFVLYLERRILYFIYHVIYPCIMMSTLTLLVFCLPPDSGEKIALGITVLLAFSVLMLSIAEKLPETSESVPLISIYLTTVMSMTSVSVIMTVFVLNLHHRGPNKSPIPKWMQRLMI-CKNRYFSCKGSLTKNRK 1186
            +E RL + L   Y P +RPV +  + V   +G+++ QI D+ EK+Q++ T+ W+ Q WY+ +L+WN + +  I ++ +   ++W PD+VLYNNA    D  +       +V +DG+  W  P    SSC I + YFPFD Q C+LKFGSWT+DGF ++L  +     L  ++ NGEW L     +RN + Y CCP PY DVTF L+L RR+L+F++++I PC ++  LT L F LPPDSGE+I++ IT LLA +V ML +A+ LP TS+ V +ISI+ +  +    ++++ T  VL  H    +   +P W++ L+I C  + F C+   T +++
Sbjct:   49 DEGRLTRDLFAGYNPKLRPVFHKRENVTVVLGMSVHQIIDVYEKDQIIKTSFWVRQIWYNPFLRWNETFYGGIKEINVSPLQVWTPDLVLYNNADASTDGSLENFKTRIIVSSDGKNMWLAPVIFSSSCTIKIKYFPFDDQYCSLKFGSWTFDGFHLDLKPEAPQASLSKFIPNGEWDLIGAPAIRNVLRYDCCPAPYPDVTFTLHLRRRVLFFLFNLIIPCFVIVVLTSLSFYLPPDSGERISVVITNLLAMTVFMLMVADILPPTSDEVSIISIFYSCSIIEVGIALLGTCIVLKYHFCSTSIHKMPPWVRFLVIECLGKVF-CRQEHTNDQE 382          
BLAST of Neuronal acetylcholine receptor subunit alpha-10 vs. Ensembl Nematostella
Match: EDO38974 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SBB9])

HSP 1 Score: 258.455 bits (659), Expect = 3.211e-81
Identity = 131/312 (41.99%), Postives = 194/312 (62.18%), Query Frame = 2
Query:  200 EHRLFKKLMKDYEPSVRPVRNSSKPVIAKMGITLTQIFDMDEKNQVLVTNVWLDQQWYDEYLQWNTSEFPSISKLRIPSEKIWKPDIVLYNNAADFADKMM---PALAMVKNDGEVFWPVPTKLKSSCKIDVTYFPFDSQICTLKFGSWTYDGFQVELDKLKGVDLDMYVENGEWKLKKTKVLRNNIVYTCCPEPYYDVTFVLYLERRILYFIYHVIYPCIMMSTLTLLVFCLPPDSGEKIALGITVLLAFSVLMLSIAEKLPETSESVPLISIYLT-TVMSMTSVSVIMTVFVLNLHHRGPNKSPIPKWMQ 1123
            E RL + L+  Y+  +RPV + ++ V     +TL QI D+ EK ++L  ++++ Q W +  L WN SE+  IS++ +  +++WKPDI LYNNA   AD  +    A   V + G   W  PT L +SCKI+V YFPFD Q CTLKFGSWTYD   V++D      +  Y +NGEW        RN   Y CCP P+ DVT  L + RR LY+  ++I PC++++ L+LL F +  +SGE+I+L IT LLA +V ML +A+ LP TSE VPLIS+++T +++ +  +S++ T FVL  +H  P+ + +P WM+
Sbjct:    1 EERLLRDLLTTYDKKLRPVIHKNETVKTIFALTLNQIIDVIEKYELLKLSLYVRQIWKNPLLSWNASEYGGISQVNLEPDQLWKPDIYLYNNADSSADGSLYGFKAKIKVSHTGLNMWLAPTILTTSCKINVKYFPFDQQSCTLKFGSWTYDAGSVDIDTSPTASIKGYQQNGEWDFISFPCKRNAQFYDCCPHPFTDVTCTLNIRRRTLYYWINLIVPCLLITVLSLLSFIVTTESGERISLVITNLLALTVFMLIVADILPPTSEVVPLISVFITSSIVQVVGLSLVATCFVLQCYHTNPDINEMPFWMR 312          
BLAST of Neuronal acetylcholine receptor subunit alpha-10 vs. Ensembl Medaka
Match: ENSORLT00000038695.1 (neuronal acetylcholine receptor subunit alpha-7-like [Source:NCBI gene;Acc:101166204])

HSP 1 Score: 321.242 bits (822), Expect = 4.088e-102
Identity = 151/314 (48.09%), Postives = 205/314 (65.29%), Query Frame = 2
Query:  194 PEEHRLFKKLMKDYEPSVRPVRNSSKPVIAKMGITLTQIFDMDEKNQVLVTNVWLDQQWYDEYLQWNTSEFPSISKLRIPSEKIWKPDIVLYNNAADFADKMMPALAMVKNDGEVFWPVPTKLKSSCKIDVTYFPFDSQICTLKFGSWTYDGFQVELDKLKGVDLDMYVENGEWKLKKTKVLRNNIVYTCCPEPYYDVTFVLYLERRILYFIYHVIYPCIMMSTLTLLVFCLPPDSGEKIALGITVLLAFSVLMLSIAEKLPETSESVPLISIYLTTVMSMTSVSVIMTVFVLNLHHRGPNKSPIPKWMQRLMI 1135
            P + RL+  LM  Y P  RPV N S+ +    G++L QI D+DEKNQVL TN+WL   W D YLQWN+S++P ++ +R P   IWKPDI+LYN+A +  D       +V + G   +  P   KS+C IDV +FPFD Q C LKFGSWTY G+ ++L  L+  D+  Y+ NGEW L +    RN   Y CC EPY D+TF + + RR LY+  +++ PC+++STL LLVF LP DSGEKI+LGITVLL+ +V ML +AE +P TS+SVPLI+ Y  T M +  +SVI TV VL  HH  P+   +PKW + +++
Sbjct:   48 PNQRRLYSDLMSTYNPLERPVYNDSQSLTVHFGLSLLQIMDVDEKNQVLTTNIWLRLYWNDHYLQWNSSDYPGVTNVRFPDHLIWKPDILLYNSADERFDATFHTNILVNSSGTCSYLPPGIFKSTCYIDVRWFPFDVQRCELKFGSWTYGGWSLDLKMLEA-DVSGYIANGEWDLVEVPGQRNERFYECCDEPYLDITFTVVMRRRTLYYGLNLLLPCVLISTLALLVFLLPADSGEKISLGITVLLSLTVFMLLVAEIMPATSDSVPLIAEYFATTMVIVGLSVIATVLVLQYHHHDPDGGKMPKWTRVILL 360          
BLAST of Neuronal acetylcholine receptor subunit alpha-10 vs. Ensembl Medaka
Match: ENSORLT00000046008.1 (neuronal acetylcholine receptor subunit alpha-7-like [Source:NCBI gene;Acc:101166204])

HSP 1 Score: 320.857 bits (821), Expect = 5.114e-102
Identity = 151/314 (48.09%), Postives = 205/314 (65.29%), Query Frame = 2
Query:  194 PEEHRLFKKLMKDYEPSVRPVRNSSKPVIAKMGITLTQIFDMDEKNQVLVTNVWLDQQWYDEYLQWNTSEFPSISKLRIPSEKIWKPDIVLYNNAADFADKMMPALAMVKNDGEVFWPVPTKLKSSCKIDVTYFPFDSQICTLKFGSWTYDGFQVELDKLKGVDLDMYVENGEWKLKKTKVLRNNIVYTCCPEPYYDVTFVLYLERRILYFIYHVIYPCIMMSTLTLLVFCLPPDSGEKIALGITVLLAFSVLMLSIAEKLPETSESVPLISIYLTTVMSMTSVSVIMTVFVLNLHHRGPNKSPIPKWMQRLMI 1135
            P + RL+  LM  Y P  RPV N S+ +    G++L QI D+DEKNQVL TN+WL   W D YLQWN+S++P ++ +R P   IWKPDI+LYN+A +  D       +V + G   +  P   KS+C IDV +FPFD Q C LKFGSWTY G+ ++L  L+  D+  Y+ NGEW L +    RN   Y CC EPY D+TF + + RR LY+  +++ PC+++STL LLVF LP DSGEKI+LGITVLL+ +V ML +AE +P TS+SVPLI+ Y  T M +  +SVI TV VL  HH  P+   +PKW + +++
Sbjct:   45 PNQRRLYSDLMSTYNPLERPVYNDSQSLTVHFGLSLLQIMDVDEKNQVLTTNIWLRLYWNDHYLQWNSSDYPGVTNVRFPDHLIWKPDILLYNSADERFDATFHTNILVNSSGTCSYLPPGIFKSTCYIDVRWFPFDVQRCELKFGSWTYGGWSLDLKMLEA-DVSGYIANGEWDLVEVPGQRNERFYECCDEPYLDITFTVVMRRRTLYYGLNLLLPCVLISTLALLVFLLPADSGEKISLGITVLLSLTVFMLLVAEIMPATSDSVPLIAEYFATTMVIVGLSVIATVLVLQYHHHDPDGGKMPKWTRVILL 357          
BLAST of Neuronal acetylcholine receptor subunit alpha-10 vs. Ensembl Medaka
Match: ENSORLT00000012478.2 (neuronal acetylcholine receptor subunit alpha-7 [Source:NCBI gene;Acc:101155633])

HSP 1 Score: 322.783 bits (826), Expect = 1.010e-101
Identity = 146/314 (46.50%), Postives = 208/314 (66.24%), Query Frame = 2
Query:  194 PEEHRLFKKLMKDYEPSVRPVRNSSKPVIAKMGITLTQIFDMDEKNQVLVTNVWLDQQWYDEYLQWNTSEFPSISKLRIPSEKIWKPDIVLYNNAADFADKMMPALAMVKNDGEVFWPVPTKLKSSCKIDVTYFPFDSQICTLKFGSWTYDGFQVELDKLKGVDLDMYVENGEWKLKKTKVLRNNIVYTCCPEPYYDVTFVLYLERRILYFIYHVIYPCIMMSTLTLLVFCLPPDSGEKIALGITVLLAFSVLMLSIAEKLPETSESVPLISIYLTTVMSMTSVSVIMTVFVLNLHHRGPNKSPIPKWMQRLMI 1135
            P +  L K+L++DY P  RPV N S+ +      TL Q+ D+DEKNQ+L TN WL  QWYD YLQWN SE+P +  LR   +++W PDI+LYN+A D  D       +V + G   +  P    S+C +DV +FPFD Q C LKFGSWT+DG+ +++ ++K  D+  Y+ NGEW L +    R+ I Y CC EPY DVTFV+ L RR L++  +++ PC+++S++TL+VF LP +SGEKI+LGITVLL+ +V ML +AE +P TS+SVPLI  Y  + M +  +SV+ TV VL  HH  PN  P+P+W+  +++
Sbjct:   23 PHQRYLLKELLRDYNPMERPVANDSQALTVHFSYTLIQVMDVDEKNQILTTNAWLQMQWYDHYLQWNQSEYPGVKNLRFSPDQVWTPDILLYNSAHDKFDATFKTNVLVNSSGFCEFLPPGIFVSTCSVDVRWFPFDIQRCELKFGSWTFDGWLLDI-QMKEADVSGYMPNGEWDLMEVPGGRHEIFYDCCAEPYPDVTFVVTLRRRTLFYALNLLIPCVLLSSMTLVVFLLPANSGEKISLGITVLLSLTVFMLMVAEIMPATSDSVPLIGQYFASTMVIVGMSVVATVIVLQFHHHTPNSGPMPRWVHLVLL 335          
BLAST of Neuronal acetylcholine receptor subunit alpha-10 vs. Ensembl Medaka
Match: si:ch211-39a7.1 (neuronal acetylcholine receptor subunit alpha-7-like [Source:NCBI gene;Acc:101160921])

HSP 1 Score: 321.242 bits (822), Expect = 1.273e-101
Identity = 151/314 (48.09%), Postives = 205/314 (65.29%), Query Frame = 2
Query:  194 PEEHRLFKKLMKDYEPSVRPVRNSSKPVIAKMGITLTQIFDMDEKNQVLVTNVWLDQQWYDEYLQWNTSEFPSISKLRIPSEKIWKPDIVLYNNAADFADKMMPALAMVKNDGEVFWPVPTKLKSSCKIDVTYFPFDSQICTLKFGSWTYDGFQVELDKLKGVDLDMYVENGEWKLKKTKVLRNNIVYTCCPEPYYDVTFVLYLERRILYFIYHVIYPCIMMSTLTLLVFCLPPDSGEKIALGITVLLAFSVLMLSIAEKLPETSESVPLISIYLTTVMSMTSVSVIMTVFVLNLHHRGPNKSPIPKWMQRLMI 1135
            P +  L K L+KDY    RPV N S  +     ++L QI D+DEKNQVL +N+WL   WYD YLQWN SE+P +  LR  S+++W PDI+LYN+A D  D       +V + G   +  P    S+C +DV +FPFD Q C LKFGSWTYDG+ ++L  ++  D+  Y+ NGEW L      RN I Y CC EPY DVTFV+ + RR LY+  +++ PC+++S++TLLVF LP DSGEKI+LGITVLL+ +V ML +AE +P TS+SVPLI  Y  ++M +  +SVI T  VL  HH  PN   +PKW+Q +++
Sbjct:   23 PHQRSLLKSLLKDYNRMERPVANDSHTLTVHFTLSLIQIMDVDEKNQVLTSNMWLQMTWYDHYLQWNQSEYPGVKNLRFTSDQVWTPDILLYNSADDDFDSTFKTNVLVNSSGYAKYLPPGIFMSTCNVDVRWFPFDIQKCNLKFGSWTYDGWLLDLQMIEA-DISSYMPNGEWDLIGVPGSRNEIFYDCCKEPYTDVTFVITIRRRTLYYALNLLIPCVLLSSMTLLVFVLPADSGEKISLGITVLLSLTVFMLLVAEIMPATSDSVPLIGQYFASIMIIVGMSVIATTVVLQYHHHDPNGGNMPKWVQLVLL 335          
BLAST of Neuronal acetylcholine receptor subunit alpha-10 vs. Ensembl Medaka
Match: si:ch211-39a7.1 (neuronal acetylcholine receptor subunit alpha-7-like [Source:NCBI gene;Acc:101160921])

HSP 1 Score: 321.242 bits (822), Expect = 4.994e-101
Identity = 151/314 (48.09%), Postives = 205/314 (65.29%), Query Frame = 2
Query:  194 PEEHRLFKKLMKDYEPSVRPVRNSSKPVIAKMGITLTQIFDMDEKNQVLVTNVWLDQQWYDEYLQWNTSEFPSISKLRIPSEKIWKPDIVLYNNAADFADKMMPALAMVKNDGEVFWPVPTKLKSSCKIDVTYFPFDSQICTLKFGSWTYDGFQVELDKLKGVDLDMYVENGEWKLKKTKVLRNNIVYTCCPEPYYDVTFVLYLERRILYFIYHVIYPCIMMSTLTLLVFCLPPDSGEKIALGITVLLAFSVLMLSIAEKLPETSESVPLISIYLTTVMSMTSVSVIMTVFVLNLHHRGPNKSPIPKWMQRLMI 1135
            P +  L K L+KDY    RPV N S  +     ++L QI D+DEKNQVL +N+WL   WYD YLQWN SE+P +  LR  S+++W PDI+LYN+A D  D       +V + G   +  P    S+C +DV +FPFD Q C LKFGSWTYDG+ ++L  ++  D+  Y+ NGEW L      RN I Y CC EPY DVTFV+ + RR LY+  +++ PC+++S++TLLVF LP DSGEKI+LGITVLL+ +V ML +AE +P TS+SVPLI  Y  ++M +  +SVI T  VL  HH  PN   +PKW+Q +++
Sbjct:   69 PHQRSLLKSLLKDYNRMERPVANDSHTLTVHFTLSLIQIMDVDEKNQVLTSNMWLQMTWYDHYLQWNQSEYPGVKNLRFTSDQVWTPDILLYNSADDDFDSTFKTNVLVNSSGYAKYLPPGIFMSTCNVDVRWFPFDIQKCNLKFGSWTYDGWLLDLQMIEA-DISSYMPNGEWDLIGVPGSRNEIFYDCCKEPYTDVTFVITIRRRTLYYALNLLIPCVLLSSMTLLVFVLPADSGEKISLGITVLLSLTVFMLLVAEIMPATSDSVPLIGQYFASIMIIVGMSVIATTVVLQYHHHDPNGGNMPKWVQLVLL 381          
BLAST of Neuronal acetylcholine receptor subunit alpha-10 vs. Planmine SMEST
Match: SMESG000028455.1 (SMESG000028455.1)

HSP 1 Score: 1178.31 bits (3047), Expect = 0.000e+0
Identity = 597/598 (99.83%), Postives = 598/598 (100.00%), Query Frame = 2
Query:   77 MVWKSVFRLANIYGLILILIVNRNTEGKSLSEVKNDENLPEEHRLFKKLMKDYEPSVRPVRNSSKPVIAKMGITLTQIFDMDEKNQVLVTNVWLDQQWYDEYLQWNTSEFPSISKLRIPSEKIWKPDIVLYNNAADFADKMMPALAMVKNDGEVFWPVPTKLKSSCKIDVTYFPFDSQICTLKFGSWTYDGFQVELDKLKGVDLDMYVENGEWKLKKTKVLRNNIVYTCCPEPYYDVTFVLYLERRILYFIYHVIYPCIMMSTLTLLVFCLPPDSGEKIALGITVLLAFSVLMLSIAEKLPETSESVPLISIYLTTVMSMTSVSVIMTVFVLNLHHRGPNKSPIPKWMQRLMICKNRYFSCKGSLTKNRKIPFKGIKNIESLLMSINSKLKQFPVKKSKSFPSPQNHVENYLNKYPNEVGLGNIKLNSYPTMETDVLSGSVTANHEYEPMFISDNDYRCTGNIIHXXXXXXXXXXXXXXXXNILINPSSPTVDKAVSTDAYPSCDNDQQEINTKILSALNRILVKHEIDESNYNLIQEWREVAQFVDRILFWLYLFXXXXXXIIVLIIAPVFGIIPINIVDPLEIRMNLTSHFNKSEG 1870
            MVWKSVFRLANIYGLIL+LIVNRNTEGKSLSEVKNDENLPEEHRLFKKLMKDYEPSVRPVRNSSKPVIAKMGITLTQIFDMDEKNQVLVTNVWLDQQWYDEYLQWNTSEFPSISKLRIPSEKIWKPDIVLYNNAADFADKMMPALAMVKNDGEVFWPVPTKLKSSCKIDVTYFPFDSQICTLKFGSWTYDGFQVELDKLKGVDLDMYVENGEWKLKKTKVLRNNIVYTCCPEPYYDVTFVLYLERRILYFIYHVIYPCIMMSTLTLLVFCLPPDSGEKIALGITVLLAFSVLMLSIAEKLPETSESVPLISIYLTTVMSMTSVSVIMTVFVLNLHHRGPNKSPIPKWMQRLMICKNRYFSCKGSLTKNRKIPFKGIKNIESLLMSINSKLKQFPVKKSKSFPSPQNHVENYLNKYPNEVGLGNIKLNSYPTMETDVLSGSVTANHEYEPMFISDNDYRCTGNIIHSRSLSLSSSSRQCLSCNILINPSSPTVDKAVSTDAYPSCDNDQQEINTKILSALNRILVKHEIDESNYNLIQEWREVAQFVDRILFWLYLFSTSTSTIIVLIIAPVFGIIPINIVDPLEIRMNLTSHFNKSEG
Sbjct:    1 MVWKSVFRLANIYGLILVLIVNRNTEGKSLSEVKNDENLPEEHRLFKKLMKDYEPSVRPVRNSSKPVIAKMGITLTQIFDMDEKNQVLVTNVWLDQQWYDEYLQWNTSEFPSISKLRIPSEKIWKPDIVLYNNAADFADKMMPALAMVKNDGEVFWPVPTKLKSSCKIDVTYFPFDSQICTLKFGSWTYDGFQVELDKLKGVDLDMYVENGEWKLKKTKVLRNNIVYTCCPEPYYDVTFVLYLERRILYFIYHVIYPCIMMSTLTLLVFCLPPDSGEKIALGITVLLAFSVLMLSIAEKLPETSESVPLISIYLTTVMSMTSVSVIMTVFVLNLHHRGPNKSPIPKWMQRLMICKNRYFSCKGSLTKNRKIPFKGIKNIESLLMSINSKLKQFPVKKSKSFPSPQNHVENYLNKYPNEVGLGNIKLNSYPTMETDVLSGSVTANHEYEPMFISDNDYRCTGNIIHSRSLSLSSSSRQCLSCNILINPSSPTVDKAVSTDAYPSCDNDQQEINTKILSALNRILVKHEIDESNYNLIQEWREVAQFVDRILFWLYLFSTSTSTIIVLIIAPVFGIIPINIVDPLEIRMNLTSHFNKSEG 598          
BLAST of Neuronal acetylcholine receptor subunit alpha-10 vs. Planmine SMEST
Match: SMESG000061503.1 (SMESG000061503.1)

HSP 1 Score: 377.867 bits (969), Expect = 6.139e-124
Identity = 205/534 (38.39%), Postives = 307/534 (57.49%), Query Frame = 2
Query:  191 LPEEHRLFKKLMKDYEPSVRPVRNSSKPVIAKMGITLTQIFDMDEKNQVLVTNVWLDQQWYDEYLQWNTSEFPSISKLRIPSEKIWKPDIVLYNNAADFADKMMPALAMVKNDGEVFWPVPTKLKSSCKIDVTYFPFDSQICTLKFGSWTYDGFQVELDKLKG-VDLDMYVENGEWKLKKTKVLRNNIVYTCCPEPYYDVTFVLYLERRILYFIYHVIYPCIMMSTLTLLVFCLPPDSGEKIALGITVLLAFSVLMLSIAEKLPETSESVPLISIYLTTVMSMTSVSVIMTVFVLNLHHRGPNKSPIPKWMQRLMICKNRYFSCKGSLTKNRKIPFKGIKNIESLLMSINSKLKQFPVKKSKSFPSPQNH----VENYLNKYPNEVGLGNIKLNSYPTMETDVLSGSVTANHEYEPMFISD--NDYRCTGNIIHXXXXXXXXXXXXXXXXNILINPSSPTVDKAVSTDAYPSCDND---------QQEIN--TKILSALNRILVKHEIDESNYNLIQEWREVAQFVDRILFWLY 1738
            +P+E +L +K++ +Y+P+ RP+ N+S  V+ K   TL QI+ +DE NQVL TNVWL+Q+W DE L WN   +  ++ +R+P EK+W PDIVLYN+A DF    M + AM+KN G+VFWP P K +S+CKID+TYFPFD Q C++KFGSWTYDG QV++ K    VD   YV +GEW+L     +RN + Y CC E Y D+TF + + RR LY+++++I PC+ ++ L+LL F LPPDSGEKI LGITVLLAFSV ML IAEK+P TSE VPLI IYLT  M+ TS+S+++TV VL++HH GP+   IP  ++RL        +    +T  R+   +  +N ES+     S+        ++  P   NH     +N+    P        K   Y  + +        +NH  + + + +  ND+  T +                       + + P   +++ +D      ++         Q  +N  ++I+  L+  + KH+ DE +   + EW+ +A  +DR LFW++
Sbjct:   27 IPDEQKLLRKILYNYDPASRPIFNASNSVVIKFQFTLIQIYKLDEVNQVLTTNVWLEQEWKDERLLWNPVYYDGLTTIRVPCEKLWLPDIVLYNSADDFTSGYMQSKAMIKNTGDVFWPPPAKFRSTCKIDITYFPFDDQSCSMKFGSWTYDGGQVDIVKRHNIVDTSNYVLSGEWQLISVVAIRNEVTYACCIEKYPDITFTIIIRRRTLYYLFNIILPCLWLTILSLLSFWLPPDSGEKITLGITVLLAFSVFMLLIAEKMPATSEFVPLIGIYLTVTMATTSLSILLTVLVLHIHHIGPHHKKIPPRLRRLFFDN---LAPILGMTTVRRYKIRK-RNNESINRGQFSQSYADKFSSNEFLPEDNNHNIGLKQNFAPPSPRNQSFSESKTGIYDCLIS-------ISNHSTDHLVVENKSNDFSNTFS----------------------CSSTPPAKKESIKSDFQVRLGDNLNLDRNLLCQSSLNQYSEIIQHLHHFIEKHQEDEFDQERMLEWKVMAYILDRFLFWIF 527          
BLAST of Neuronal acetylcholine receptor subunit alpha-10 vs. Planmine SMEST
Match: SMESG000068777.1 (SMESG000068777.1)

HSP 1 Score: 285.804 bits (730), Expect = 1.723e-88
Identity = 180/572 (31.47%), Postives = 294/572 (51.40%), Query Frame = 2
Query:   77 MVWKSVFRLANIYGLILILI----VNRNTEGKSLSEVKNDENLPEEHRLFKKLMKDYEPSVRPVRNSSKPVIAKMGITLTQIFDMDEKNQVLVTNVWLDQQWYDEYLQWNTSEFPSISKLRIPSEKIWKPDIVLYNNAADFADKMMPALAMVKNDGEVFWPVPTKLKSSCKIDVTYFPFDSQICTLKFGSWTYDGFQVEL---------DKLKGV-------DLDMYVENGEWKLKKTKVLRNNIVYTCCPEPYYDVTFVLYLERRILYFIYHVIYPCIMMSTLTLLVFCLPPDSGEKIALGITVLLAFSVLMLSIAEKLPETSESVPLISIYLTTVMSMTSVSVIMTVFVLNLHHRGPNKSPIPKWMQRLMICKNRYFSCKGSLTKNRKIPFKGIKNIESLLMSINSKLKQFPVKKSKSFPSPQNHV--ENYLNKYPNEVGLGNIKLNSYPTMETDVLSGSVTANHE--YEPMFISDNDYRCTGNIIHXXXXXXXXXXXXXXXXNILINPSSPTVDKAVSTDAYPSCDNDQQEINTKILSALNRILVKHEIDESNYNLIQEWREVAQFVDR 1720
            M    +F   N     LILI     +     K L     D+N P+ H + +          RP +N S+PV  +M   LTQ+ D+DEKNQ++ TN+WLD +W D + QWN S +  IS  +IP++++WKPD++L+N+A D  D   P   +VKN   + W  P   KS+C ID+T+FPFDSQ CT+KFGSWTY G  ++L         ++  GV       +L+ YV NGE+ +    +  N + Y+   E Y ++   + ++R+ LY+I+++I PC+++ST+ LL F LPPD+GEKI+LG+T+LL+ ++ +L +A+KLP+TS ++ L+ IY   +M M S+S++ TV VLN HHR  N  P+P  ++++                                  +N+ L +    K  S P  +N +  +N L     E GL         ++  +     + AN +  +  +F  ++D+R     +H    S +S     +   +    +  ++    S   +PSC++  + I   IL  L +I  K + DE    + +EW+  A+ +DR
Sbjct:    1 MTESKIFGFCNFAVFWLILISLSEFHCGINEKKLLRYLFDQNRPDAHNILE----------RPSKNDSQPVEVRMKAFLTQLIDVDEKNQIIHTNIWLDLKWKDYHFQWNPSVYGGISGFKIPADRVWKPDLLLFNSADDKFDGTYPTNVVVKNSSLMQWVPPGMFKSTCDIDITWFPFDSQNCTVKFGSWTYSGKYIDLRLQCPDDDDNEKTGVCTETSVINLESYVLNGEFDIVDCPI--NRLQYSFNNETYMNILMTIRMQRKPLYYIFNLIIPCVLISTMALLEFTLPPDAGEKISLGVTILLSMTMFLLLVADKLPQTSGAISLLGIYFACIMFMCSLSIVFTVLVLNYHHRSVNLKPVPPLIKKI----------------------------------VNTWLAKVLFMKQNSEPEIRNELFQKNDLGSEMIENGL---------SVNFEKCRSPIDANSKFTFSHVFDVESDFR-----VHGIGKSKTSFRLPKVPSYMSFKGAENSIPPKTSKATWPSCNSRHELI--AILDELKKITQKIKDDEDEITMAKEWKFAARVIDR 510          
BLAST of Neuronal acetylcholine receptor subunit alpha-10 vs. Planmine SMEST
Match: SMESG000068777.1 (SMESG000068777.1)

HSP 1 Score: 285.804 bits (730), Expect = 2.275e-88
Identity = 180/572 (31.47%), Postives = 294/572 (51.40%), Query Frame = 2
Query:   77 MVWKSVFRLANIYGLILILI----VNRNTEGKSLSEVKNDENLPEEHRLFKKLMKDYEPSVRPVRNSSKPVIAKMGITLTQIFDMDEKNQVLVTNVWLDQQWYDEYLQWNTSEFPSISKLRIPSEKIWKPDIVLYNNAADFADKMMPALAMVKNDGEVFWPVPTKLKSSCKIDVTYFPFDSQICTLKFGSWTYDGFQVEL---------DKLKGV-------DLDMYVENGEWKLKKTKVLRNNIVYTCCPEPYYDVTFVLYLERRILYFIYHVIYPCIMMSTLTLLVFCLPPDSGEKIALGITVLLAFSVLMLSIAEKLPETSESVPLISIYLTTVMSMTSVSVIMTVFVLNLHHRGPNKSPIPKWMQRLMICKNRYFSCKGSLTKNRKIPFKGIKNIESLLMSINSKLKQFPVKKSKSFPSPQNHV--ENYLNKYPNEVGLGNIKLNSYPTMETDVLSGSVTANHE--YEPMFISDNDYRCTGNIIHXXXXXXXXXXXXXXXXNILINPSSPTVDKAVSTDAYPSCDNDQQEINTKILSALNRILVKHEIDESNYNLIQEWREVAQFVDR 1720
            M    +F   N     LILI     +     K L     D+N P+ H + +          RP +N S+PV  +M   LTQ+ D+DEKNQ++ TN+WLD +W D + QWN S +  IS  +IP++++WKPD++L+N+A D  D   P   +VKN   + W  P   KS+C ID+T+FPFDSQ CT+KFGSWTY G  ++L         ++  GV       +L+ YV NGE+ +    +  N + Y+   E Y ++   + ++R+ LY+I+++I PC+++ST+ LL F LPPD+GEKI+LG+T+LL+ ++ +L +A+KLP+TS ++ L+ IY   +M M S+S++ TV VLN HHR  N  P+P  ++++                                  +N+ L +    K  S P  +N +  +N L     E GL         ++  +     + AN +  +  +F  ++D+R     +H    S +S     +   +    +  ++    S   +PSC++  + I   IL  L +I  K + DE    + +EW+  A+ +DR
Sbjct:   16 MTESKIFGFCNFAVFWLILISLSEFHCGINEKKLLRYLFDQNRPDAHNILE----------RPSKNDSQPVEVRMKAFLTQLIDVDEKNQIIHTNIWLDLKWKDYHFQWNPSVYGGISGFKIPADRVWKPDLLLFNSADDKFDGTYPTNVVVKNSSLMQWVPPGMFKSTCDIDITWFPFDSQNCTVKFGSWTYSGKYIDLRLQCPDDDDNEKTGVCTETSVINLESYVLNGEFDIVDCPI--NRLQYSFNNETYMNILMTIRMQRKPLYYIFNLIIPCVLISTMALLEFTLPPDAGEKISLGVTILLSMTMFLLLVADKLPQTSGAISLLGIYFACIMFMCSLSIVFTVLVLNYHHRSVNLKPVPPLIKKI----------------------------------VNTWLAKVLFMKQNSEPEIRNELFQKNDLGSEMIENGL---------SVNFEKCRSPIDANSKFTFSHVFDVESDFR-----VHGIGKSKTSFRLPKVPSYMSFKGAENSIPPKTSKATWPSCNSRHELI--AILDELKKITQKIKDDEDEITMAKEWKFAARVIDR 525          
BLAST of Neuronal acetylcholine receptor subunit alpha-10 vs. Planmine SMEST
Match: SMESG000011827.1 (SMESG000011827.1)

HSP 1 Score: 282.337 bits (721), Expect = 2.403e-87
Identity = 132/315 (41.90%), Postives = 207/315 (65.71%), Query Frame = 2
Query:  248 RPVRNSSKPVIAKMGITLTQIFDMDEKNQVLVTNVWLDQQWYDEYLQWNTSEFPSISKLRIPSEKIWKPDIVLYNNAADFADKMMPALAMVKNDGEVFWPVPTKLKSSCKIDVTYFPFDSQICTLKFGSWTYDG----FQVELD-------KLKGVDLDMYVENGEWKLKKTKVLRNNIVYTCCPE-PYYDVTFVLYLERRILYFIYHVIYPCIMMSTLTLLVFCLPPDSGEKIALGITVLLAFSVLMLSIAEKLPETSESVPLISIYLTTVMSMTSVSVIMTVFVLNLHHRGPNKSPIPKWMQRLMICKNRYFS 1156
            RPV + ++ +  +  +TL QI D+DEKNQV+ TN+WLD  W D   +WN  EF +I+ L +PSEK+WKPDI++YN+A +  D   PA  +V N G +    P   KS+CKI++T+FPFD Q C +KFG+WTY G    F+++ D       +    D + +++NGEW++      ++   Y CCPE P+ D+ F + + R+ LY+I++++ PCI++ST++LLVF LPP +GEKI +G+T++L+ ++ +  +A+KLP+TS SVPLI +Y + +M M S SV+ TV VLN HH+      +P W++ L+   NR+ +
Sbjct:   41 RPVVDENQSLEVQFKVTLLQILDLDEKNQVMNTNIWLDITWTDYNFKWNPLEFGNITTLILPSEKVWKPDILMYNSADEKFDGTYPANVVVTNQGLMHMVPPGMFKSTCKINITWFPFDQQSCVMKFGTWTYTGDKVDFRLKCDEGSNCTGQYGSADTESFLKNGEWEIVDVPAEKHTETYPCCPESPFIDIKFHVKMRRKALYYIFNLMTPCIIISTMSLLVFTLPPGAGEKITMGVTIMLSLTMFLFMVADKLPQTSGSVPLIGLYFSCIMIMCSFSVVFTVLVLNCHHKSGEDEEMPYWLKVLV---NRWLA 352          
The following BLAST results are available for this feature:
BLAST of Neuronal acetylcholine receptor subunit alpha-10 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
CHRNA71.450e-9947.12cholinergic receptor nicotinic alpha 7 subunit [So... [more]
AC243734.11.450e-9947.12cholinergic receptor nicotinic alpha 7 subunit [So... [more]
CHRNA75.248e-9947.12cholinergic receptor nicotinic alpha 7 subunit [So... [more]
AC254952.12.447e-9846.47cholinergic receptor nicotinic alpha 7 subunit [So... [more]
AC254952.12.447e-9846.47cholinergic receptor nicotinic alpha 7 subunit [So... [more]
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BLAST of Neuronal acetylcholine receptor subunit alpha-10 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
acr-191.112e-9544.84AcetylCholine Receptor [Source:UniProtKB/TrEMBL;A... [more]
acr-191.502e-9544.84AcetylCholine Receptor [Source:UniProtKB/TrEMBL;A... [more]
acr-161.553e-9545.86Acetylcholine receptor subunit alpha-type acr-16 ... [more]
acr-211.468e-9039.55pep chromosome:WBcel235:III:6581927:6586549:1 gene... [more]
acr-211.559e-9039.55pep chromosome:WBcel235:III:6581927:6586549:1 gene... [more]
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BLAST of Neuronal acetylcholine receptor subunit alpha-10 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
nAChRalpha76.802e-10442.44gene:FBgn0086778 transcript:FBtr0301835[more]
nAChRalpha77.689e-10442.44gene:FBgn0086778 transcript:FBtr0301834[more]
nAChRalpha77.689e-10442.44gene:FBgn0086778 transcript:FBtr0343798[more]
nAChRalpha77.689e-10442.44gene:FBgn0086778 transcript:FBtr0074680[more]
nAChRalpha51.022e-10045.89gene:FBgn0028875 transcript:FBtr0300594[more]
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BLAST of Neuronal acetylcholine receptor subunit alpha-10 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
si:ch211-39a7.11.391e-10247.45si:ch211-39a7.1 [Source:ZFIN;Acc:ZDB-GENE-060503-6... [more]
chrna72.219e-10148.43cholinergic receptor, nicotinic, alpha 7 (neuronal... [more]
chrna72.530e-10148.43cholinergic receptor, nicotinic, alpha 7 (neuronal... [more]
CR847523.33.125e-10044.69neuronal acetylcholine receptor subunit alpha-10-l... [more]
FO907089.11.734e-9847.48neuronal acetylcholine receptor subunit alpha-7-li... [more]
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BLAST of Neuronal acetylcholine receptor subunit alpha-10 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ENSXETT00000021532.12.822e-10248.72cholinergic receptor, nicotinic alpha 7 [Source:NC... [more]
prepl5.680e-9744.23prolyl endopeptidase-like [Source:Xenbase;Acc:XB-G... [more]
CHRNA95.895e-9540.68cholinergic receptor, nicotinic alpha 9 [Source:NC... [more]
CHRNA97.241e-9540.68cholinergic receptor, nicotinic alpha 9 [Source:NC... [more]
CHRNA91.109e-9444.52cholinergic receptor, nicotinic alpha 9 [Source:NC... [more]
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BLAST of Neuronal acetylcholine receptor subunit alpha-10 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Chrna73.246e-10047.44cholinergic receptor, nicotinic, alpha polypeptide... [more]
Chrna31.548e-9346.52cholinergic receptor, nicotinic, alpha polypeptide... [more]
Chrna104.264e-9341.57cholinergic receptor, nicotinic, alpha polypeptide... [more]
Chrna35.866e-9346.52cholinergic receptor, nicotinic, alpha polypeptide... [more]
Chrna37.430e-9346.52cholinergic receptor, nicotinic, alpha polypeptide... [more]
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BLAST of Neuronal acetylcholine receptor subunit alpha-10 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q05941|ACHA7_RAT1.935e-9947.44Neuronal acetylcholine receptor subunit alpha-7 OS... [more]
sp|P49582|ACHA7_MOUSE2.271e-9947.44Neuronal acetylcholine receptor subunit alpha-7 OS... [more]
sp|P22770|ACHA7_CHICK4.844e-9947.12Neuronal acetylcholine receptor subunit alpha-7 OS... [more]
sp|P36544|ACHA7_HUMAN6.961e-9947.12Neuronal acetylcholine receptor subunit alpha-7 OS... [more]
sp|Q9I8C7|ACH10_CHICK1.421e-9845.19Neuronal acetylcholine receptor subunit alpha-10 O... [more]
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BLAST of Neuronal acetylcholine receptor subunit alpha-10 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A210QVT82.800e-17248.19Neuronal acetylcholine receptor subunit alpha-10 O... [more]
K1QFA07.085e-17049.91Neuronal acetylcholine receptor subunit alpha-2 OS... [more]
A0A1I8J9821.689e-16874.45Uncharacterized protein OS=Macrostomum lignano OX=... [more]
A0A1I8H6J31.400e-15872.44Uncharacterized protein OS=Macrostomum lignano OX=... [more]
R7V7D54.929e-15747.43Uncharacterized protein OS=Capitella teleta OX=283... [more]
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BLAST of Neuronal acetylcholine receptor subunit alpha-10 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
chrna74.061e-10145.19neuronal acetylcholine receptor subunit alpha-7-li... [more]
chrna77.235e-10047.80neuronal acetylcholine receptor subunit alpha-7-li... [more]
ENSAMXT00000019858.28.631e-9945.19neuronal acetylcholine receptor subunit alpha-10 [... [more]
chrna73.785e-9847.70neuronal acetylcholine receptor subunit alpha-7-li... [more]
ENSAMXT00000032409.15.568e-9845.19neuronal acetylcholine receptor subunit alpha-10 [... [more]
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BLAST of Neuronal acetylcholine receptor subunit alpha-10 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5
Match NameE-valueIdentityDescription
chrna36.444e-9245.05cholinergic receptor, nicotinic, alpha 3 [Source:Z... [more]
chrnb3b7.389e-8242.72cholinergic receptor, nicotinic, beta 3b (neuronal... [more]
chrna2a3.725e-7847.50cholinergic receptor, nicotinic, alpha 2a (neurona... [more]
ENSPMAT00000008550.15.238e-7146.12pep scaffold:Pmarinus_7.0:GL476601:34:38373:1 gene... [more]
ENSPMAT00000000149.13.484e-6248.79pep scaffold:Pmarinus_7.0:GL480219:31373:46583:1 g... [more]
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BLAST of Neuronal acetylcholine receptor subunit alpha-10 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Neuronal acetylcholine receptor subunit alpha-10 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO420541.456e-8841.77Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO436426.357e-8543.55Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO455641.629e-8340.32Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO420389.414e-8239.10Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO389743.211e-8141.99Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Neuronal acetylcholine receptor subunit alpha-10 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ENSORLT00000038695.14.088e-10248.09neuronal acetylcholine receptor subunit alpha-7-li... [more]
ENSORLT00000046008.15.114e-10248.09neuronal acetylcholine receptor subunit alpha-7-li... [more]
ENSORLT00000012478.21.010e-10146.50neuronal acetylcholine receptor subunit alpha-7 [S... [more]
si:ch211-39a7.11.273e-10148.09neuronal acetylcholine receptor subunit alpha-7-li... [more]
si:ch211-39a7.14.994e-10148.09neuronal acetylcholine receptor subunit alpha-7-li... [more]
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BLAST of Neuronal acetylcholine receptor subunit alpha-10 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000028455.10.000e+099.83SMESG000028455.1[more]
SMESG000061503.16.139e-12438.39SMESG000061503.1[more]
SMESG000068777.11.723e-8831.47SMESG000068777.1[more]
SMESG000068777.12.275e-8831.47SMESG000068777.1[more]
SMESG000011827.12.403e-8741.90SMESG000011827.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30028579 ID=SMED30028579|Name=Neuronal acetylcholine receptor subunit alpha-10|organism=Schmidtea mediterranea sexual|type=transcript|length=1887bp
GAAAAATTTTTACTTCTTTCGGATGAAAATGATTAGACAAGGAAATAATC
TTTTGTAAAAATAAAGTAATGTAATTATGGTGTGGAAATCCGTATTTCGG
CTTGCAAATATTTACGGACTGATTCTTATTTTAATTGTTAATAGAAACAC
TGAGGGGAAAAGTTTATCGGAAGTAAAAAACGATGAGAATTTACCGGAAG
AACACAGACTTTTTAAAAAGTTAATGAAAGATTATGAGCCATCCGTTCGA
CCGGTACGCAATTCATCAAAGCCTGTGATTGCCAAAATGGGAATAACTCT
TACCCAAATATTTGATATGGATGAAAAGAATCAAGTTCTTGTGACAAATG
TTTGGCTTGACCAACAATGGTACGATGAATATTTGCAATGGAATACAAGC
GAATTCCCTTCAATTTCTAAATTGCGAATTCCGTCAGAAAAAATTTGGAA
GCCTGATATTGTTCTTTACAACAATGCTGCCGATTTTGCAGATAAAATGA
TGCCAGCTTTAGCGATGGTAAAAAATGATGGAGAGGTCTTTTGGCCTGTT
CCTACTAAATTAAAAAGTTCTTGTAAAATCGATGTCACCTATTTTCCTTT
TGATAGCCAAATATGCACGTTGAAGTTTGGATCTTGGACTTATGATGGGT
TTCAGGTTGAATTGGACAAATTGAAAGGGGTTGACTTAGATATGTATGTG
GAAAATGGGGAATGGAAACTCAAAAAAACTAAAGTTTTACGAAATAACAT
TGTTTACACATGCTGTCCTGAGCCATACTACGACGTGACTTTTGTCTTAT
ATCTAGAAAGGCGGATCTTATATTTTATTTACCATGTCATTTATCCATGT
ATCATGATGTCAACTTTGACTCTTCTTGTGTTTTGTTTGCCACCAGATTC
CGGTGAGAAAATTGCTCTCGGAATTACAGTGTTGCTAGCATTTTCCGTCC
TAATGCTGAGTATAGCTGAAAAGCTACCTGAAACATCAGAATCTGTACCT
TTAATAAGTATTTATTTAACGACTGTCATGTCCATGACTTCCGTTTCTGT
TATTATGACAGTTTTCGTTCTTAATCTGCATCATAGAGGTCCAAATAAAA
GCCCCATTCCAAAGTGGATGCAGAGGTTAATGATTTGTAAAAATAGATAT
TTTTCCTGCAAAGGTTCTCTCACAAAAAACCGAAAAATACCATTCAAAGG
AATAAAAAATATCGAGTCTCTTTTAATGTCAATCAATAGTAAATTAAAAC
AATTTCCAGTGAAAAAAAGTAAATCTTTTCCAAGTCCTCAAAATCACGTG
GAGAATTATTTAAACAAATACCCAAATGAGGTGGGCTTGGGAAACATCAA
ACTGAATTCGTATCCAACTATGGAAACTGACGTTTTGAGTGGATCTGTCA
CTGCTAACCATGAATATGAGCCAATGTTCATTTCTGATAATGATTATCGT
TGCACTGGAAATATCATTCACTCGCGTTCATTAAGCTTATCTTCTTCATC
CAGACAATGCCTATCATGTAACATTTTGATAAATCCAAGTTCGCCGACCG
TAGATAAAGCAGTTTCAACTGACGCATATCCGTCCTGTGACAACGATCAA
CAAGAAATCAACACAAAGATTCTTTCTGCCTTGAATAGAATATTAGTCAA
GCATGAAATAGACGAATCGAACTATAATTTGATTCAAGAATGGCGTGAAG
TCGCTCAATTTGTCGACCGAATATTGTTTTGGCTTTACTTGTTTTCAACG
TCTACTTCAACAATAATTGTTCTAATTATAGCCCCTGTTTTTGGGATAAT
ACCAATAAATATTGTTGATCCTCTTGAAATACGAATGAACTTGACTTCTC
ACTTCAATAAGTCAGAAGGATGATCAGATTAGTTCCT
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protein sequence of SMED30028579-orf-1

>SMED30028579-orf-1 ID=SMED30028579-orf-1|Name=SMED30028579-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=599bp
MVWKSVFRLANIYGLILILIVNRNTEGKSLSEVKNDENLPEEHRLFKKLM
KDYEPSVRPVRNSSKPVIAKMGITLTQIFDMDEKNQVLVTNVWLDQQWYD
EYLQWNTSEFPSISKLRIPSEKIWKPDIVLYNNAADFADKMMPALAMVKN
DGEVFWPVPTKLKSSCKIDVTYFPFDSQICTLKFGSWTYDGFQVELDKLK
GVDLDMYVENGEWKLKKTKVLRNNIVYTCCPEPYYDVTFVLYLERRILYF
IYHVIYPCIMMSTLTLLVFCLPPDSGEKIALGITVLLAFSVLMLSIAEKL
PETSESVPLISIYLTTVMSMTSVSVIMTVFVLNLHHRGPNKSPIPKWMQR
LMICKNRYFSCKGSLTKNRKIPFKGIKNIESLLMSINSKLKQFPVKKSKS
FPSPQNHVENYLNKYPNEVGLGNIKLNSYPTMETDVLSGSVTANHEYEPM
FISDNDYRCTGNIIHSRSLSLSSSSRQCLSCNILINPSSPTVDKAVSTDA
YPSCDNDQQEINTKILSALNRILVKHEIDESNYNLIQEWREVAQFVDRIL
FWLYLFSTSTSTIIVLIIAPVFGIIPINIVDPLEIRMNLTSHFNKSEG*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: molecular function
TermDefinition
GO:0004888transmembrane signaling receptor activity
GO:0005216ion channel activity
GO:0004889acetylcholine-activated cation-selective channel activity
GO:0005230extracellular ligand-gated ion channel activity
GO:0022848acetylcholine-gated cation-selective channel activity
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000070intestinal phagocyte
PLANA:0000418head
Vocabulary: INTERPRO
TermDefinition
IPR036734Neur_chan_lig-bd_sf
IPR036719Neuro-gated_channel_TM_sf
IPR006201Neur_channel
IPR002394Nicotinic_acetylcholine_rcpt
IPR006202Neur_chan_lig-bd
IPR027361Acetylcholine_rcpt_TM
IPR006029Neurotrans-gated_channel_TM
IPR018000Neurotransmitter_ion_chnl_CS
Vocabulary: biological process
TermDefinition
GO:0006811ion transport
GO:0006810transport
GO:0034220ion transmembrane transport
GO:0060078regulation of postsynaptic membrane potential
GO:0060079excitatory postsynaptic potential
Vocabulary: cellular component
TermDefinition
GO:0016021integral component of membrane
GO:0045211postsynaptic membrane
GO:0016020membrane
GO:0005886plasma membrane
GO:0030054cell junction
GO:0045202synapse
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR002394Nicotinic acetylcholine receptorPRINTSPR00254NICOTINICRcoord: 76..92
score: 45.69
coord: 128..140
score: 45.38
coord: 110..124
score: 40.37
coord: 146..164
score: 34.33
IPR006201Neurotransmitter-gated ion-channelPRINTSPR00252NRIONCHANNELcoord: 122..133
score: 56.26
coord: 166..180
score: 53.94
coord: 89..105
score: 40.06
coord: 241..253
score: 28.47
IPR006201Neurotransmitter-gated ion-channelTIGRFAMTIGR00860TIGR00860coord: 31..568
e-value: 1.0E-103
score: 345.5
IPR006201Neurotransmitter-gated ion-channelPANTHERPTHR18945NEUROTRANSMITTER GATED ION CHANNELcoord: 43..349
IPR006029Neurotransmitter-gated ion-channel transmembrane domainPFAMPF02932Neur_chan_membcoord: 254..565
e-value: 2.0E-40
score: 139.3
NoneNo IPR availableGENE3DG3DSA:1.20.58.390coord: 253..366
e-value: 5.3E-37
score: 128.6
NoneNo IPR availablePANTHERPTHR18945:SF825NICOTINIC ACETYLCHOLINE RECEPTOR ALPHA5, ISOFORM Bcoord: 43..349
NoneNo IPR availableCDDcd19051LGIC_TM_cationcoord: 248..337
e-value: 3.06474E-42
score: 145.583
NoneNo IPR availableCDDcd18997LGIC_ECD_nAChRcoord: 67..246
e-value: 1.07723E-96
score: 290.931
NoneNo IPR availableSIGNALP_EUKSignalP-noTMSignalP-noTMcoord: 1..27
score: 0.609
NoneNo IPR availableTMHMMTMhelixcoord: 278..297
NoneNo IPR availableTMHMMTMhelixcoord: 550..572
NoneNo IPR availableTMHMMTMhelixcoord: 249..271
NoneNo IPR availableTMHMMTMhelixcoord: 312..334
IPR036734Neurotransmitter-gated ion-channel ligand-binding domain superfamilyGENE3DG3DSA:2.70.170.10coord: 31..252
e-value: 3.6E-83
score: 280.4
IPR036734Neurotransmitter-gated ion-channel ligand-binding domain superfamilySUPERFAMILYSSF63712Nicotinic receptor ligand binding domain-likecoord: 41..246
IPR006202Neurotransmitter-gated ion-channel ligand-binding domainPFAMPF02931Neur_chan_LBDcoord: 43..246
e-value: 2.5E-66
score: 223.2
IPR018000Neurotransmitter-gated ion-channel, conserved sitePROSITEPS00236NEUROTR_ION_CHANNELcoord: 166..180
IPR036719Neurotransmitter-gated ion-channel transmembrane domain superfamilySUPERFAMILYSSF90112Neurotransmitter-gated ion-channel transmembrane porecoord: 248..572