Serine/threonine-protein phosphatase with EF-hands
Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30028575 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 11
Homology
BLAST of Serine/threonine-protein phosphatase with EF-hands vs. Ensembl Human
Match: PPEF1 (protein phosphatase with EF-hand domain 1 [Source:HGNC Symbol;Acc:HGNC:9243]) HSP 1 Score: 551.206 bits (1419), Expect = 0.000e+0 Identity = 279/641 (43.53%), Postives = 401/641 (62.56%), Query Frame = 1 Query: 253 SIKAAILIQNWYRRYRAKLEAKRRYTWMIYQSIEYSGEQDQLKLQSFFNDLLSLTNKGQECDSEVIEALSKTHV------LKTAPTVSDEDRDLQYLTKIEQIVVEPTYKGAKLTFPLSINQVTALIESFRKEQILHARYLLELLDHTRNLLKTKPNVSQASTSISKRVTICGDLHGQLDDLVTIFYKNKFPDTSNPYIINGDFVDRGSHSVEIAAILFSFFLLYPQSVFLNRGNHEDHVMNYRYGFVKEIQIKYKSNANKIVRFFADIFSWLPLMTIIDNSILVCHGGISAMLNLDVIEKLDRHKFLSVLQAPVEDIKNEN----------------------------KEEEWMQILDLLWSDPRSKPGCSVNQYRGGGCYFGPDITNDILKKYNLSLLIRSHECKIDGYEWCHENKVVTLFSASNYYKQGSNKGAFLRIDNEHNKQFFQYTTHKKNQKHLTLIQSVNQIEESALRDLKGKILAFKNELAEEFIQKDVNNRGVIELQEWCTVMENVLKLPLPWRTLRPHLVKLSKEGKVEYSSIFEAQQVDNKFLMIAGTMTEELYKNKENLETIFRIMDKDNSGHISLSEFRDACKLLHRHTNRNVSEEAIEDLAKCLDINKDGQIDFNEFLEAFRIV 2073 S++AA++IQNWYR Y+A+L+A++ Y I+QSIEY+ EQ Q++L +FF+ +L + TH+ L+ S++D ++ ++ I V +Y G +L FPL+ + L+E+F+++QILHA Y+LE+L T+ +LK PN + TS SK VTICGDLHG+LDDL IFYKN P NPY+ NGDFVDRG +S+EI IL FL+YP + LNRGNHED +MN RYGF KEI KYK + +I++ + ++WLP+ TI+DN ILV HGGIS +L+++ +++R+K SVL P E ++ + E EW QI+D+LWSDPR K GC N RGGGCYFGPD+T+ IL KY L +LIRSHECK +GYE CH+ KVVT+FSASNYY++GSN+GA++++ + +FFQY K L Q V+ +E SA++ L+ ++++ K++L F +D G + + +W MEN+L L LPWR+L +LV + + G VEY S F+ +++ T+ E LY+ + +LE IF +D D+SG IS+ EFR KL H N ++ + + LA +D+NKDG IDFNEFL+AF +V Sbjct: 16 SLRAALIIQNWYRGYKARLKARQHYALTIFQSIEYADEQGQMQLSTFFSFMLE----------------NYTHIHKEELELRNQSLESEQDMRDRW-DYVDSIDVPDSYNGPRLQFPLTCTDIDLLLEAFKEQQILHAHYVLEVLFETKKVLKQMPNFTHIQTSPSKEVTICGDLHGKLDDLFLIFYKNGLPSERNPYVFNGDFVDRGKNSIEILMILCVSFLVYPNDLHLNRGNHEDFMMNLRYGFTKEILHKYKLHGKRILQILEEFYAWLPIGTIVDNEILVIHGGISETTDLNLLHRVERNKMKSVLIPPTETNRDHDTDSKHNKVGVTFNAHGRIKTNGSPTEHLTEHEWEQIIDILWSDPRGKNGCFPNTCRGGGCYFGPDVTSKILNKYQLKMLIRSHECKPEGYEICHDGKVVTIFSASNYYEEGSNRGAYIKLCSGTTPRFFQYQVTKATCFQ-PLRQRVDTMENSAIKILRERVISRKSDLTRAFQLQDHRKSGKLSVSQWAFCMENILGLNLPWRSLSSNLVNIDQNGNVEYMSSFQNIRIEKPVQEAHSTLVETLYRYRSDLEIIFNAIDTDHSGLISVEEFRAMWKLFSSHYNVHIDDSQVNKLANIMDLNKDGSIDFNEFLKAFYVV 638
BLAST of Serine/threonine-protein phosphatase with EF-hands vs. Ensembl Human
Match: PPEF1 (protein phosphatase with EF-hand domain 1 [Source:HGNC Symbol;Acc:HGNC:9243]) HSP 1 Score: 443.736 bits (1140), Expect = 6.117e-147 Identity = 242/613 (39.48%), Postives = 365/613 (59.54%), Query Frame = 1 Query: 253 SIKAAILIQNWYRRYRAKLEAKRRYTWMIYQSIEYSGEQDQLKLQSFFNDLLSLTNKGQECDSEVIEALSKTHV------LKTAPTVSDEDRDLQYLTKIEQIVVEPTYKGAKLTFPLSINQVTALIESFRKEQILHARYLLELLDHTRNLLKTKPNVSQASTSISKRVTICGDLHGQLDDLVTIFYKNKFPDTSNPYIINGDFVDRGSHSVEIAAILFSFFLLYPQSVFLNRGNHEDHVMNYRYGFVKEIQIKYKSNANKIVRFFADIFSWLPLMTIIDNSILVCHGGISAMLNLDVIEKLDRHKFLSVLQAPVEDIKNENKEEEWMQILDLLWSDPRSKPGCSVNQYRGGGCYFGPDITNDILKKYNLSLLIRSHECKIDGYEWCHENKVVTLFSASNYYKQGSNKGAFLRIDNEHNKQFFQYTTHKKNQKHLTLIQSVNQIEESALRDLKGKILAFKNELAEEFIQKDVNNRGVIELQEWCTVMENVLKLPLPWRTLRPHLVKLSKEGKVEYSSIFEAQQVDNKFLMIAGTMTEELYKNKENLETIFRIMDKDNSGHISLSEFRDACKLLHRHTNRNVSEEAIEDLAKCLDINKDGQIDFNEFLEAFRIV 2073 S++AA++IQNWYR Y+A+L+A++ Y I+QSIEY+ EQ Q++L +FF+ +L + TH+ L+ S++D ++ ++ I V +Y G +L FPL+ + L+E+F+++QILHA Y+LE+L T+ +LK PN + TS SK VTICGDLHG+LDDL IFYKN P NPY+ NGDFVDRG +S+EI IL FL+YP + LNRGNHED +MN RYGF KEI KYK + +I++ + ++WLP+ TI+DN ILV HGGIS +L+++ +++R+K SVL P E ++ + + + +K G + N + G TN S + +EW +VVT+FSASNYY++GSN+GA++++ + +FFQY K L Q V+ +E SA++ L+ ++++ K++L F +D G + + +W MEN+L L LPWR+L +LV + + G VEY S F+ +++ T+ E LY+ + +LE IF +D D+SG IS+ EFR KL H N ++ + + LA +D+NKDG IDFNEFL+AF +V Sbjct: 16 SLRAALIIQNWYRGYKARLKARQHYALTIFQSIEYADEQGQMQLSTFFSFMLE----------------NYTHIHKEELELRNQSLESEQDMRDRW-DYVDSIDVPDSYNGPRLQFPLTCTDIDLLLEAFKEQQILHAHYVLEVLFETKKVLKQMPNFTHIQTSPSKEVTICGDLHGKLDDLFLIFYKNGLPSERNPYVFNGDFVDRGKNSIEILMILCVSFLVYPNDLHLNRGNHEDFMMNLRYGFTKEILHKYKLHGKRILQILEEFYAWLPIGTIVDNEILVIHGGISETTDLNLLHRVERNKMKSVLIPPTETNRDHDTDSK------------HNKVGVTFNAH-------GRIKTNG------------SPTEHLTEHEW---EQVVTIFSASNYYEEGSNRGAYIKLCSGTTPRFFQYQVTKATCFQ-PLRQRVDTMENSAIKILRERVISRKSDLTRAFQLQDHRKSGKLSVSQWAFCMENILGLNLPWRSLSSNLVNIDQNGNVEYMSSFQNIRIEKPVQEAHSTLVETLYRYRSDLEIIFNAIDTDHSGLISVEEFRAMWKLFSSHYNVHIDDSQVNKLANIMDLNKDGSIDFNEFLKAFYVV 576
BLAST of Serine/threonine-protein phosphatase with EF-hands vs. Ensembl Human
Match: PPEF2 (protein phosphatase with EF-hand domain 2 [Source:HGNC Symbol;Acc:HGNC:9244]) HSP 1 Score: 307.375 bits (786), Expect = 1.667e-94 Identity = 148/320 (46.25%), Postives = 209/320 (65.31%), Query Frame = 1 Query: 253 SIKAAILIQNWYRRYRAKLEAKRRYTWMIYQSIEYSGEQDQLKLQSFFNDLLSLTNKGQECDSEVIEALSKTHVLKTAPTVSDEDRDLQYLTKIEQIVVEPTYKGAKLTFPLSINQVTALIESFRKEQILHARYLLELLDHTRNLLKTKPNVSQASTSISKRVTICGDLHGQLDDLVTIFYKNKFPDTSNPYIINGDFVDRGSHSVEIAAILFSFFLLYPQSVFLNRGNHEDHVMNYRYGFVKEIQIKYKSNANKIVRFFADIFSWLPLMTIIDNSILVCHGGISAMLNLDVIEKLDRHKFLSVLQAPVEDIKNENKEEE 1212 + KAA LIQ WYRRY A+LE +RR TW I+QSIEY+G+QDQ+KL FF+ L+ D + + + +D +++ + E I V +Y G +L+FPL + TAL+E+FR +Q LHARY+L LL T+ L PN+++ ST S+ +T+CGDLHGQLDDL+ IFYKN P Y+ NGDFVDRG SVEI ILF+F L+YP+ LNRGNHEDH++N RYGF KE+ KYK + +I+R D+F WLPL T+ID +L+ HGG+S + +L++++K++R K +S ++ K+E + EE Sbjct: 19 AFKAAALIQRWYRRYVARLEMRRRCTWSIFQSIEYAGQQDQVKLHDFFSYLMDHFIPSSHNDRDFLTRIFTEDRFA-------QDSEMKKCSDYESIEVPDSYTGPRLSFPLLPDHATALVEAFRLKQQLHARYVLNLLYETKKHLVQLPNINRVSTCYSEEITVCGDLHGQLDDLIFIFYKNGLPSPERSYVFNGDFVDRGKDSVEILMILFAFMLVYPKEFHLNRGNHEDHMVNLRYGFTKEVMNKYKVHGKEILRTLQDVFCWLPLATLIDEKVLILHGGVSDITDLELLDKIERSKIVSTMRCKTRQ-KSEKQMEE 330 HSP 2 Score: 176.407 bits (446), Expect = 1.736e-46 Identity = 77/158 (48.73%), Postives = 110/158 (69.62%), Query Frame = 1 Query: 1204 EEEWMQILDLLWSDPRSKPGCSVNQYRGGGCYFGPDITNDILKKYNLSLLIRSHECKIDGYEWCHENKVVTLFSASNYYKQGSNKGAFLRIDNEHNKQFFQYTTHKKNQKHLTLIQSVNQIEESALRDLKGKILAFKNELAEEFIQKDVNNRGVIELQ 1677 +EEW Q++D+LWSDP ++ GC N RGGGCYFGPD+T +L+KYN+ LIRSHECK +GYE+CH KV+T+FSASNYY+ GSN+GA++++ QY +K LT+ Q ++++EESALR L+ K+ A ++L EF + D + G+ Q Sbjct: 435 QEEWRQVVDILWSDPMAQEGCKANTIRGGGCYFGPDVTQQLLQKYNMQFLIRSHECKPEGYEFCHNRKVLTIFSASNYYEVGSNRGAYVKLGPALTPHIVQYQANKVTHT-LTMRQRISRVEESALRALREKLFAHSSDLLSEFKKHDADKVGLASSQ 591
BLAST of Serine/threonine-protein phosphatase with EF-hands vs. Ensembl Human
Match: PPEF2 (protein phosphatase with EF-hand domain 2 [Source:HGNC Symbol;Acc:HGNC:9244]) HSP 1 Score: 306.99 bits (785), Expect = 1.088e-92 Identity = 148/320 (46.25%), Postives = 209/320 (65.31%), Query Frame = 1 Query: 253 SIKAAILIQNWYRRYRAKLEAKRRYTWMIYQSIEYSGEQDQLKLQSFFNDLLSLTNKGQECDSEVIEALSKTHVLKTAPTVSDEDRDLQYLTKIEQIVVEPTYKGAKLTFPLSINQVTALIESFRKEQILHARYLLELLDHTRNLLKTKPNVSQASTSISKRVTICGDLHGQLDDLVTIFYKNKFPDTSNPYIINGDFVDRGSHSVEIAAILFSFFLLYPQSVFLNRGNHEDHVMNYRYGFVKEIQIKYKSNANKIVRFFADIFSWLPLMTIIDNSILVCHGGISAMLNLDVIEKLDRHKFLSVLQAPVEDIKNENKEEE 1212 + KAA LIQ WYRRY A+LE +RR TW I+QSIEY+G+QDQ+KL FF+ L+ D + + + +D +++ + E I V +Y G +L+FPL + TAL+E+FR +Q LHARY+L LL T+ L PN+++ ST S+ +T+CGDLHGQLDDL+ IFYKN P Y+ NGDFVDRG SVEI ILF+F L+YP+ LNRGNHEDH++N RYGF KE+ KYK + +I+R D+F WLPL T+ID +L+ HGG+S + +L++++K++R K +S ++ K+E + EE Sbjct: 19 AFKAAALIQRWYRRYVARLEMRRRCTWSIFQSIEYAGQQDQVKLHDFFSYLMDHFIPSSHNDRDFLTRIFTEDRFA-------QDSEMKKCSDYESIEVPDSYTGPRLSFPLLPDHATALVEAFRLKQQLHARYVLNLLYETKKHLVQLPNINRVSTCYSEEITVCGDLHGQLDDLIFIFYKNGLPSPERSYVFNGDFVDRGKDSVEILMILFAFMLVYPKEFHLNRGNHEDHMVNLRYGFTKEVMNKYKVHGKEILRTLQDVFCWLPLATLIDEKVLILHGGVSDITDLELLDKIERSKIVSTMRCKTRQ-KSEKQMEE 330 HSP 2 Score: 305.064 bits (780), Expect = 4.709e-92 Identity = 145/296 (48.99%), Postives = 202/296 (68.24%), Query Frame = 1 Query: 1204 EEEWMQILDLLWSDPRSKPGCSVNQYRGGGCYFGPDITNDILKKYNLSLLIRSHECKIDGYEWCHENKVVTLFSASNYYKQGSNKGAFLRIDNEHNKQFFQYTTHKKNQKHLTLIQSVNQIEESALRDLKGKILAFKNELAEEFIQKDVNNRGVIELQEWCTVMENVLKLPLPWRTLRPHLVKLSKEGKVEYSSIFE---AQQVDNKFLMIAGTMTEELYKNKENLETIFRIMDKDNSGHISLSEFRDACKLLHRHTNRNVSEEAIEDLAKCLDINKDGQIDFNEFLEAFRIVDSS 2082 +EEW Q++D+LWSDP ++ GC N RGGGCYFGPD+T +L+KYN+ LIRSHECK +GYE+CH KV+T+FSASNYY+ GSN+GA++++ QY +K LT+ Q ++++EESALR L+ K+ A ++L EF + D + G+I L +W +E+VL L LPWR LRP LV S + +EY S + +Q+ + I ++ E LY+N+ NLETIFRI+D D+SG ISL EFR KL H N +++++ I DLA+ +D NKDG ID NEFLEAFR+V+ S Sbjct: 435 QEEWRQVVDILWSDPMAQEGCKANTIRGGGCYFGPDVTQQLLQKYNMQFLIRSHECKPEGYEFCHNRKVLTIFSASNYYEVGSNRGAYVKLGPALTPHIVQYQANKVTHT-LTMRQRISRVEESALRALREKLFAHSSDLLSEFKKHDADKVGLITLSDWAAAVESVLHLGLPWRMLRPQLVNSSADNMLEYKSWLKNLAKEQLSRE--NIQSSLLETLYRNRSNLETIFRIIDSDHSGFISLDEFRQTWKLFSSHMNIDITDDCICDLARSIDFNKDGHIDINEFLEAFRLVEKS 727
BLAST of Serine/threonine-protein phosphatase with EF-hands vs. Ensembl Human
Match: PPP5C (protein phosphatase 5 catalytic subunit [Source:HGNC Symbol;Acc:HGNC:9322]) HSP 1 Score: 231.876 bits (590), Expect = 3.497e-67 Identity = 133/369 (36.04%), Postives = 204/369 (55.28%), Query Frame = 1 Query: 421 KGQECDSEVIEALSKTHVLKTAPTVSDEDRDLQYLTKIEQIVVEPTYKGAKLT-FPLSINQVTALIESFRKEQILHARYLLELLDHTRNLLKTKPNVSQASTSISKRVTICGDLHGQLDDLVTIFYKNKFPDTSNPYIINGDFVDRGSHSVEIAAILFSFFLLYPQSVFLNRGNHEDHVMNYRYGFVKEIQIKYKSNANKIVRFFADIFSWLPLMTIIDNSILVCHGGISA--MLNLDVIEKLDRHKFLSVLQAPVEDIKNENKEEEWMQILDLLWSDPRSKPGCSVNQYRGGGCYFGPDITNDILKKYNLSLLIRSHECKIDGYEWCHENKVVTLFSASNYYKQGSNKGAFLRID-NEHNKQFFQYTT 1515 K QEC+ V K + A + R + IE + +E Y G KL ++I+ + L++ ++ ++ LH + ++L + +L + + + ++++T+CGD HGQ DL+ IF N P +NPYI NGDFVDRGS SVE+ LF F LLYP L RGNHE MN YGF E++ KY + ++ F+++F WLPL I+ +L+ HGG+ + + LD I K++R++ Q P + + DLLWSDP+ + G S+++ RG C FGPD+T L++ NL +IRSHE K +GYE H + VT+FSA NY Q NK +++ + ++ QF Q+T Sbjct: 135 KYQECNKIV-----KQKAFERAIAGDEHKRSVVDSLDIESMTIEDEYSGPKLEDGKVTISFMKELMQWYKDQKKLHRKCAYQILVQVKEVLSKLSTLVETTLKETEKITVCGDTHGQFYDLLNIFELNGLPSETNPYIFNGDFVDRGSFSVEVILTLFGFKLLYPDHFHLLRGNHETDNMNQIYGFEGEVKAKYTA---QMYELFSEVFEWLPLAQCINGKVLIMHGGLFSEDGVTLDDIRKIERNR-----QPP-----------DSGPMCDLLWSDPQPQNGRSISK-RGVSCQFGPDVTKAFLEENNLDYIIRSHEVKAEGYEVAHGGRCVTVFSAPNYCDQMGNKASYIHLQGSDLRPQFHQFTA 478
BLAST of Serine/threonine-protein phosphatase with EF-hands vs. Ensembl Celegans
Match: pef-1 (Serine/threonine-protein phosphatase with EF-hands pef-1 [Source:UniProtKB/Swiss-Prot;Acc:G5EBX9]) HSP 1 Score: 569.696 bits (1467), Expect = 0.000e+0 Identity = 288/646 (44.58%), Postives = 405/646 (62.69%), Query Frame = 1 Query: 229 STGDTGP---ISIKAAILIQNWYRRYRAKLEAKRRYTWMIYQSIEYSGEQDQLKLQSFFNDLLSL----TNKG---QECDSEVIEALSKTHVLKTAPTVSDED----RDLQYLTKIEQIVVEPTYKGAKLTFPLSINQVTALIESFRKEQILHARYLLELLDHTRNLLKTKPNVSQASTSISKRVTICGDLHGQLDDLVTIFYKNKFPDTSNPYIINGDFVDRGSHSVEIAAILFSFFLLYPQSVFLNRGNHEDHVMNYRYGFVKEIQIKYKSNANKIVRFFADIFSWLPLMTIIDNSILVCHGGISAMLNLDVIEKLDRHKFLSVLQAPVEDIKNENKE------EEWMQILDLLWSDPRSKPGCSVNQYRGGGCYFGPDITNDILKKYNLSLLIRSHECKIDGYEWCHENKVVTLFSASNYYKQGSNKGAFLR-IDNEHNKQFFQYTTHKKNQKHLTLIQSVNQIEESALRDLKGKILAFKNELAEEFIQKDVNNRGVIELQEWCTVMENVLKLPLPWRTLRPHLVKLSKEGKVEYSSIFEAQQVDNKFLMIAGT------MTEELYKNKENLETIFRIMDKDNSGHISLSEFRDACKLLHRHTNRNVSEEAIEDLAKCLDINKDGQIDFNEFLEAFRIVDSSL 2085 S+G P ++IK+AILIQ WYRR A+LEA+RR TW I+ ++EY+GEQDQLKL FF D++ KG +S ++ ALS H K P++ D + + + T + ++ YKG L+ PL QV +IE+F+ ++LH +Y+L +L R + K P+VS+ STSIS +VTICGDLHG+ DDL I YKN +P NPYI NGDFVDRG S+E+ +LF+ ++ P S++LNRGNHEDH+MN RYGF+KE+ KYK + I R D+FSWLP+ TIID I V HGGIS + ++K+ RH+F SVL+ PV KE +EW Q+LD++WSDP+ GC N +RGGG YFG DIT L+K+ LL+RSHECK +GYE+ H N +T+FSASNYY+ GSN+GA+++ I F QY K ++K TL + + +EESA+++LK K+ +F +L +EF D+ G + + +W +E + L LPW L P + LS++GK + + D + + GT + E LY++K LET+FR MDKDNSG +S+ EF DAC++L ++T R + + I +A+ +D NKDG ID NE LEAFR+VD L Sbjct: 6 SSGRQNPSTELTIKSAILIQKWYRRCEARLEARRRATWQIFTALEYAGEQDQLKLYDFFADVIRAMAEENGKGGVENGRNSPLMSALS--HYAK--PSLMDSEGETVKKMLEDTSPTNVDIDRNYKGPTLSLPLDKPQVAKMIEAFKVNKVLHPKYVLMILHEARKIFKAMPSVSRISTSISNQVTICGDLHGKFDDLCIILYKNGYPSVDNPYIFNGDFVDRGGQSIEVLCVLFALVIVDPMSIYLNRGNHEDHIMNLRYGFIKELSTKYKDLSTPITRLLEDVFSWLPIATIIDRDIFVVHGGISDQTEVSKLDKIPRHRFQSVLRPPVNKGMESEKENSAVNVDEWKQMLDIMWSDPKQNKGCWPNVFRGGGSYFGADITASFLEKHGFRLLVRSHECKFEGYEFSHNNTCLTVFSASNYYETGSNRGAYVKFIGKSKQPHFVQYMASKTHRKS-TLRERLGVVEESAVKELKEKLSSFHTDLQKEFEIMDIEKSGKLPILKWSDCVERITGLNLPWIALAPKVATLSEDGK------YVMYKEDRRIAQVGGTHAQEKDIVESLYRHKSTLETLFRFMDKDNSGQVSMKEFIDACEVLGKYTKRPLQTDYISQIAESIDFNKDGFIDLNELLEAFRLVDRPL 640
BLAST of Serine/threonine-protein phosphatase with EF-hands vs. Ensembl Celegans
Match: pef-1 (Serine/threonine-protein phosphatase with EF-hands pef-1 [Source:UniProtKB/Swiss-Prot;Acc:G5EBX9]) HSP 1 Score: 568.926 bits (1465), Expect = 0.000e+0 Identity = 285/636 (44.81%), Postives = 401/636 (63.05%), Query Frame = 1 Query: 250 ISIKAAILIQNWYRRYRAKLEAKRRYTWMIYQSIEYSGEQDQLKLQSFFNDLLSL----TNKG---QECDSEVIEALSKTHVLKTAPTVSDED----RDLQYLTKIEQIVVEPTYKGAKLTFPLSINQVTALIESFRKEQILHARYLLELLDHTRNLLKTKPNVSQASTSISKRVTICGDLHGQLDDLVTIFYKNKFPDTSNPYIINGDFVDRGSHSVEIAAILFSFFLLYPQSVFLNRGNHEDHVMNYRYGFVKEIQIKYKSNANKIVRFFADIFSWLPLMTIIDNSILVCHGGISAMLNLDVIEKLDRHKFLSVLQAPVEDIKNENKE------EEWMQILDLLWSDPRSKPGCSVNQYRGGGCYFGPDITNDILKKYNLSLLIRSHECKIDGYEWCHENKVVTLFSASNYYKQGSNKGAFLR-IDNEHNKQFFQYTTHKKNQKHLTLIQSVNQIEESALRDLKGKILAFKNELAEEFIQKDVNNRGVIELQEWCTVMENVLKLPLPWRTLRPHLVKLSKEGKVEYSSIFEAQQVDNKFLMIAGT------MTEELYKNKENLETIFRIMDKDNSGHISLSEFRDACKLLHRHTNRNVSEEAIEDLAKCLDINKDGQIDFNEFLEAFRIVDSSL 2085 ++IK+AILIQ WYRR A+LEA+RR TW I+ ++EY+GEQDQLKL FF D++ KG +S ++ ALS H K P++ D + + + T + ++ YKG L+ PL QV +IE+F+ ++LH +Y+L +L R + K P+VS+ STSIS +VTICGDLHG+ DDL I YKN +P NPYI NGDFVDRG S+E+ +LF+ ++ P S++LNRGNHEDH+MN RYGF+KE+ KYK + I R D+FSWLP+ TIID I V HGGIS + ++K+ RH+F SVL+ PV KE +EW Q+LD++WSDP+ GC N +RGGG YFG DIT L+K+ LL+RSHECK +GYE+ H N +T+FSASNYY+ GSN+GA+++ I F QY K ++K TL + + +EESA+++LK K+ +F +L +EF D+ G + + +W +E + L LPW L P + LS++GK + + D + + GT + E LY++K LET+FR MDKDNSG +S+ EF DAC++L ++T R + + I +A+ +D NKDG ID NE LEAFR+VD L Sbjct: 81 LTIKSAILIQKWYRRCEARLEARRRATWQIFTALEYAGEQDQLKLYDFFADVIRAMAEENGKGGVENGRNSPLMSALS--HYAK--PSLMDSEGETVKKMLEDTSPTNVDIDRNYKGPTLSLPLDKPQVAKMIEAFKVNKVLHPKYVLMILHEARKIFKAMPSVSRISTSISNQVTICGDLHGKFDDLCIILYKNGYPSVDNPYIFNGDFVDRGGQSIEVLCVLFALVIVDPMSIYLNRGNHEDHIMNLRYGFIKELSTKYKDLSTPITRLLEDVFSWLPIATIIDRDIFVVHGGISDQTEVSKLDKIPRHRFQSVLRPPVNKGMESEKENSAVNVDEWKQMLDIMWSDPKQNKGCWPNVFRGGGSYFGADITASFLEKHGFRLLVRSHECKFEGYEFSHNNTCLTVFSASNYYETGSNRGAYVKFIGKSKQPHFVQYMASKTHRKS-TLRERLGVVEESAVKELKEKLSSFHTDLQKEFEIMDIEKSGKLPILKWSDCVERITGLNLPWIALAPKVATLSEDGK------YVMYKEDRRIAQVGGTHAQEKDIVESLYRHKSTLETLFRFMDKDNSGQVSMKEFIDACEVLGKYTKRPLQTDYISQIAESIDFNKDGFIDLNELLEAFRLVDRPL 705
BLAST of Serine/threonine-protein phosphatase with EF-hands vs. Ensembl Celegans
Match: pef-1 (Serine/threonine-protein phosphatase with EF-hands pef-1 [Source:UniProtKB/Swiss-Prot;Acc:G5EBX9]) HSP 1 Score: 505.368 bits (1300), Expect = 9.763e-172 Identity = 247/548 (45.07%), Postives = 343/548 (62.59%), Query Frame = 1 Query: 481 TAPTVSDEDRDLQYLTKIEQIVVEPTYKGAKLTFPLSINQVTALIESFRKEQILHARYLLELLDHTRNLLKTKPNVSQASTSISKRVTICGDLHGQLDDLVTIFYKNKFPDTSNPYIINGDFVDRGSHSVEIAAILFSFFLLYPQSVFLNRGNHEDHVMNYRYGFVKEIQIKYKSNANKIVRFFADIFSWLPLMTIIDNSILVCHGGISAMLNLDVIEKLDRHKFLSVLQAPVEDIKNENKE------EEWMQILDLLWSDPRSKPGCSVNQYRGGGCYFGPDITNDILKKYNLSLLIRSHECKIDGYEWCHENKVVTLFSASNYYKQGSNKGAFLR-IDNEHNKQFFQYTTHKKNQKHLTLIQSVNQIEESALRDLKGKILAFKNELAEEFIQKDVNNRGVIELQEWCTVMENVLKLPLPWRTLRPHLVKLSKEGKVEYSSIFEAQQVDNKFLMIAGT------MTEELYKNKENLETIFRIMDKDNSGHISLSEFRDACKLLHRHTNRNVSEEAIEDLAKCLDINKDGQIDFNEFLEAFRIVDSSL 2085 T+PT D DR+ YKG L+ PL QV +IE+F+ ++LH +Y+L +L R + K P+VS+ STSIS +VTICGDLHG+ DDL I YKN +P NPYI NGDFVDRG S+E+ +LF+ ++ P S++LNRGNHEDH+MN RYGF+KE+ KYK + I R D+FSWLP+ TIID I V HGGIS + ++K+ RH+F SVL+ PV KE +EW Q+LD++WSDP+ GC N +RGGG YFG DIT L+K+ LL+RSHECK +GYE+ H N +T+FSASNYY+ GSN+GA+++ I F QY K ++K TL + + +EESA+++LK K+ +F +L +EF D+ G + + +W +E + L LPW L P + LS++GK + + D + + GT + E LY++K LET+FR MDKDNSG +S+ EF DAC++L ++T R + + I +A+ +D NKDG ID NE LEAFR+VD L Sbjct: 45 TSPTNVDIDRN---------------YKGPTLSLPLDKPQVAKMIEAFKVNKVLHPKYVLMILHEARKIFKAMPSVSRISTSISNQVTICGDLHGKFDDLCIILYKNGYPSVDNPYIFNGDFVDRGGQSIEVLCVLFALVIVDPMSIYLNRGNHEDHIMNLRYGFIKELSTKYKDLSTPITRLLEDVFSWLPIATIIDRDIFVVHGGISDQTEVSKLDKIPRHRFQSVLRPPVNKGMESEKENSAVNVDEWKQMLDIMWSDPKQNKGCWPNVFRGGGSYFGADITASFLEKHGFRLLVRSHECKFEGYEFSHNNTCLTVFSASNYYETGSNRGAYVKFIGKSKQPHFVQYMASKTHRKS-TLRERLGVVEESAVKELKEKLSSFHTDLQKEFEIMDIEKSGKLPILKWSDCVERITGLNLPWIALAPKVATLSEDGK------YVMYKEDRRIAQVGGTHAQEKDIVESLYRHKSTLETLFRFMDKDNSGQVSMKEFIDACEVLGKYTKRPLQTDYISQIAESIDFNKDGFIDLNELLEAFRLVDRPL 570
BLAST of Serine/threonine-protein phosphatase with EF-hands vs. Ensembl Celegans
Match: pph-5 (Serine/threonine-protein phosphatase 5 [Source:UniProtKB/Swiss-Prot;Acc:Q9NES8]) HSP 1 Score: 245.743 bits (626), Expect = 8.489e-73 Identity = 147/408 (36.03%), Postives = 215/408 (52.70%), Query Frame = 1 Query: 274 IQNWYRRYRAKLEAKR-RYTWMIYQSIEYSGEQDQLKLQSFFNDLLSLTNKGQECDSEVIEALSKTHVLKTAPTVSDEDRDLQYLTKIEQIVVEPTYKGAKLTFPLSINQVTALIESFRKEQILHARYLLELLDHTRNLLKTKPNVSQASTSISKRVTICGDLHGQLDDLVTIFYKNKFPDTSNPYIINGDFVDRGSHSVEIAAILFSFFLLYPQSVFLNRGNHEDHVMNYRYGFVKEIQIKYKSNANKIVRFFADIFSWLPLMTIIDNSILVCHGGI--SAMLNLDVIEKLDRHKFLSVLQAPVEDIKNENKEEEWMQILDLLWSDPRSKPGCSVNQYRGGGCYFGPDITNDILKKYNLSLLIRSHECKIDGYEWCHENKVVTLFSASNYYKQGSNKGAFLRIDNEH 1488 ++ +YRR A + R + YQ++ D+ F D S + Q+ ++ A+S H KT D I + +E +Y G +L ++ V LI++F+ +Q LH +Y ++L N +K+ P + + + K+ TICGD+HGQ DL IF N +P +NPY+ NGDFVDRGS SVE + F LLYP F++RGNHE VMN YGF E++ KY ++ F + F WLPL +I+ I VCHGG+ + L+ I K DR++ Q P E I + DLLWSDP+ G S ++ RG GC FGPD+T+ + + ++RSHE K +GYE H + T+FSA NY Q +NKGAF+ I ++ Sbjct: 96 VKGFYRRATANMALGRFKKALTDYQAVVKVCPNDKDARAKF--DECSKIVRRQKFEA----AISTDHDKKTVAETLD----------INAMAIEDSYDGPRLEDKITKEFVLQLIKTFKNQQKLHKKYAFKMLLEFYNYVKSLPTMVEITVPTGKKFTICGDVHGQFYDLCNIFEINGYPSETNPYLFNGDFVDRGSFSVETIFTMIGFKLLYPNHFFMSRGNHESDVMNKMYGFEGEVKAKY---TQQMCDMFTETFCWLPLCHLINEKIFVCHGGLFKEDGVTLEDIRKTDRNR-----QPPDEGI-----------MCDLLWSDPQPINGRSPSK-RGVGCQFGPDVTSKWCETNGIEYVVRSHEVKPEGYEMHHNGQCFTVFSAPNYCDQMNNKGAFITITGDN 467
BLAST of Serine/threonine-protein phosphatase with EF-hands vs. Ensembl Celegans
Match: C47A4.3 (Serine/threonine-protein phosphatase [Source:UniProtKB/TrEMBL;Acc:Q9U3L7]) HSP 1 Score: 181.03 bits (458), Expect = 4.596e-51 Identity = 103/294 (35.03%), Postives = 160/294 (54.42%), Query Frame = 1 Query: 634 QILHARYLLELLDHTRNLLKT-KPNVSQASTSISKRVTICGDLHGQLDDLVTIFYKNKFPDTSNPYIINGDFVDRGSHSVEIAAILFSFFLLYPQSVFLNRGNHEDHVMNYRYGFVKEIQIKYKSNANKIVRFFADIFSWLPLMTIIDNSILVCHGGISAMLN----LDVIEKLDRHKFLSVLQAPVEDIKNENKEEEWMQILDLLWSDPRSKPGCSVNQYRGGGCYFGPDITNDILKKYNLSLLIRSHECKIDGYEWCHENKVVTLFSASNYYKQGSNKGAFLRIDNEHNKQF 1500 +++ +L+LLD + K KP V ++ + +CGD+HGQ DL+ +F++ +P T+N Y+ GD+VDRG S+E +L ++ + +P + FL RGNHE +N YGF +E Q +Y+S ++ F D+F+WLPL +I IL HGG+S ++ LD + K++R E KE + DLLW+DP S +N RG GC FG D ++ ++ L L+ R+H+ DGYE+ K+VT+FSA +Y Q N AF+ D + F Sbjct: 25 KVITEERVLKLLDLALGVFKAQKPMVE-----VNAPIKVCGDIHGQFPDLLRLFHRGGWPPTAN-YLFLGDYVDRGRFSIETIVLLLAYKVKFPCNFFLLRGNHECEFVNKTYGFYEECQKRYQSV--RMYAAFQDVFNWLPLTGLIATKILCMHGGLSPLMTKEFTLDTLRKIER--------------PTEGKEG---LVADLLWADPISGLSGFMNNQRGAGCGFGRDSVLNLCSEFQLDLVCRAHQVVQDGYEFFAGRKLVTIFSAPHYCGQFDNCAAFMSCDEKLQCSF 293
BLAST of Serine/threonine-protein phosphatase with EF-hands vs. Ensembl Fly
Match: rdgC (gene:FBgn0265959 transcript:FBtr0342946) HSP 1 Score: 514.612 bits (1324), Expect = 6.464e-174 Identity = 258/612 (42.16%), Postives = 387/612 (63.24%), Query Frame = 1 Query: 253 SIKAAILIQNWYRRYRAKLEAKRRYTWMIYQSIEYSGEQDQLKLQSFFNDLLSLTNKGQECDSEVIEALSKTHVLKTAPTVSDEDRDLQYLTKIEQIVVEPTYKGAKLTFPLSINQVTALIESFRKEQ--ILHARYLLELLDHTRNLLKTKPNVSQASTSISKRVTICGDLHGQLDDLVTIFYKNKFPDTSNPYIINGDFVDRGSHSVEIAAILFSFFLLYPQSVFLNRGNHEDHVMNYRYGFVKEIQIKYKSNANKIVRFFADIFSWLPLMTIIDNSILVCHGGISAMLNLDVIEKLDRHKFLSVLQAPVEDIKNENKEEEWMQILDLLWSDPRSKPGCSVNQYRGGGCYFGPDITNDILKKYNLSLLIRSHECKIDGYEWCHENKVVTLFSASNYYKQGSNKGAFLRIDNEHNKQFFQYTTHKKNQKHLTLIQSVNQIEESALRDLKGKILAFKNELAEEFIQKDVNNRGVIELQEWCTVMENVLKLPLPWRTLRPHLVKLSKEGKVEYSSIFEAQQVDNKFLMIAGTMT--EELYKNKENLETIFRIMDKDNSGHISLSEFRDACKLLHRHTNRNVSEEAIEDLAKCLDINKDGQIDFNEFLEAFRIVD 2076 +I+AAI IQ WYRR++A+ E +RR W I+Q++EY+ EQDQ +L FFNDL+ + +A + + + + VS D + + IV AK+ P+ N + LI+ FRK++ LH +Y+ +L LK PN+S ST++S++VT+CGDLHG+LDDL+ + +KN P +SNPY+ NGDFVDRG +E+ +L S +L +P +VFLNRGNHED VMN RYGF++E++ KY N +I+ F +++ WLPL +++++ +L+ HGG S +LD+I+ +DR K++S+L+ P+ D + +K EW QI D++WSDP++ GC N RG G +FGPD+T++ L+++ LS +IRSHECK +G+E+ H+NK++T+FSASNYY GSNKGA++R++N+ F QY + K L+ Q + +E SAL++L ++ ++EL +EF + D + G I + WC VMENV KL LPWR LR L + KV Y+ + D A M+ + LY NK +L IF I+D DNSG I+L EF A LL H S+ + + + +D+N DG++D NEFLEAFR+ D Sbjct: 5 AIRAAIFIQKWYRRHQARREMQRRCNWQIFQNLEYASEQDQAELYKFFNDLIK----------HMPQAAGRKNQYQGSAHVSVLDDKDDLVEEFGDIV------NAKIELPIRKNHIDLLIDVFRKKRGNRLHPKYVALILREAAKSLKQLPNISPVSTAVSQQVTVCGDLHGKLDDLLVVLHKNGLPSSSNPYVFNGDFVDRGKRGLEVLLLLLSLYLAFPNAVFLNRGNHEDSVMNARYGFIREVESKYPRNHKRILAFIDEVYRWLPLGSVLNSRVLIVHGGFSDSTSLDLIKSIDRGKYVSILRPPLTDGEPLDK-TEWQQIFDIMWSDPQATMGCVPNTLRGAGVWFGPDVTDNFLQRHRLSYVIRSHECKPNGHEFMHDNKIITIFSASNYYAIGSNKGAYIRLNNQLMPHFVQYISAASQTKRLSFKQRMGIVESSALKELAVRMRDHRDELEDEFRKYDPKDSGYISISHWCKVMENVTKLGLPWRLLRDKLAPGTDSQKVNYNRTLDLLDTDVILEAEADGMSVMDALYANKASLVAIFNIIDADNSGEITLDEFETAIDLLVAHMPGAYSKAEMLEKCRMMDLNGDGKVDLNEFLEAFRLSD 599
BLAST of Serine/threonine-protein phosphatase with EF-hands vs. Ensembl Fly
Match: rdgC (gene:FBgn0265959 transcript:FBtr0473730) HSP 1 Score: 514.227 bits (1323), Expect = 1.536e-173 Identity = 258/612 (42.16%), Postives = 387/612 (63.24%), Query Frame = 1 Query: 253 SIKAAILIQNWYRRYRAKLEAKRRYTWMIYQSIEYSGEQDQLKLQSFFNDLLSLTNKGQECDSEVIEALSKTHVLKTAPTVSDEDRDLQYLTKIEQIVVEPTYKGAKLTFPLSINQVTALIESFRKEQ--ILHARYLLELLDHTRNLLKTKPNVSQASTSISKRVTICGDLHGQLDDLVTIFYKNKFPDTSNPYIINGDFVDRGSHSVEIAAILFSFFLLYPQSVFLNRGNHEDHVMNYRYGFVKEIQIKYKSNANKIVRFFADIFSWLPLMTIIDNSILVCHGGISAMLNLDVIEKLDRHKFLSVLQAPVEDIKNENKEEEWMQILDLLWSDPRSKPGCSVNQYRGGGCYFGPDITNDILKKYNLSLLIRSHECKIDGYEWCHENKVVTLFSASNYYKQGSNKGAFLRIDNEHNKQFFQYTTHKKNQKHLTLIQSVNQIEESALRDLKGKILAFKNELAEEFIQKDVNNRGVIELQEWCTVMENVLKLPLPWRTLRPHLVKLSKEGKVEYSSIFEAQQVDNKFLMIAGTMT--EELYKNKENLETIFRIMDKDNSGHISLSEFRDACKLLHRHTNRNVSEEAIEDLAKCLDINKDGQIDFNEFLEAFRIVD 2076 +I+AAI IQ WYRR++A+ E +RR W I+Q++EY+ EQDQ +L FFNDL+ + +A + + + + VS D + + IV AK+ P+ N + LI+ FRK++ LH +Y+ +L LK PN+S ST++S++VT+CGDLHG+LDDL+ + +KN P +SNPY+ NGDFVDRG +E+ +L S +L +P +VFLNRGNHED VMN RYGF++E++ KY N +I+ F +++ WLPL +++++ +L+ HGG S +LD+I+ +DR K++S+L+ P+ D + +K EW QI D++WSDP++ GC N RG G +FGPD+T++ L+++ LS +IRSHECK +G+E+ H+NK++T+FSASNYY GSNKGA++R++N+ F QY + K L+ Q + +E SAL++L ++ ++EL +EF + D + G I + WC VMENV KL LPWR LR L + KV Y+ + D A M+ + LY NK +L IF I+D DNSG I+L EF A LL H S+ + + + +D+N DG++D NEFLEAFR+ D Sbjct: 21 TIRAAIFIQKWYRRHQARREMQRRCNWQIFQNLEYASEQDQAELYKFFNDLIK----------HMPQAAGRKNQYQGSAHVSVLDDKDDLVEEFGDIV------NAKIELPIRKNHIDLLIDVFRKKRGNRLHPKYVALILREAAKSLKQLPNISPVSTAVSQQVTVCGDLHGKLDDLLVVLHKNGLPSSSNPYVFNGDFVDRGKRGLEVLLLLLSLYLAFPNAVFLNRGNHEDSVMNARYGFIREVESKYPRNHKRILAFIDEVYRWLPLGSVLNSRVLIVHGGFSDSTSLDLIKSIDRGKYVSILRPPLTDGEPLDK-TEWQQIFDIMWSDPQATMGCVPNTLRGAGVWFGPDVTDNFLQRHRLSYVIRSHECKPNGHEFMHDNKIITIFSASNYYAIGSNKGAYIRLNNQLMPHFVQYISAASQTKRLSFKQRMGIVESSALKELAVRMRDHRDELEDEFRKYDPKDSGYISISHWCKVMENVTKLGLPWRLLRDKLAPGTDSQKVNYNRTLDLLDTDVILEAEADGMSVMDALYANKASLVAIFNIIDADNSGEITLDEFETAIDLLVAHMPGAYSKAEMLEKCRMMDLNGDGKVDLNEFLEAFRLSD 615
BLAST of Serine/threonine-protein phosphatase with EF-hands vs. Ensembl Fly
Match: rdgC (gene:FBgn0265959 transcript:FBtr0342949) HSP 1 Score: 514.998 bits (1325), Expect = 6.070e-173 Identity = 258/612 (42.16%), Postives = 387/612 (63.24%), Query Frame = 1 Query: 253 SIKAAILIQNWYRRYRAKLEAKRRYTWMIYQSIEYSGEQDQLKLQSFFNDLLSLTNKGQECDSEVIEALSKTHVLKTAPTVSDEDRDLQYLTKIEQIVVEPTYKGAKLTFPLSINQVTALIESFRKEQ--ILHARYLLELLDHTRNLLKTKPNVSQASTSISKRVTICGDLHGQLDDLVTIFYKNKFPDTSNPYIINGDFVDRGSHSVEIAAILFSFFLLYPQSVFLNRGNHEDHVMNYRYGFVKEIQIKYKSNANKIVRFFADIFSWLPLMTIIDNSILVCHGGISAMLNLDVIEKLDRHKFLSVLQAPVEDIKNENKEEEWMQILDLLWSDPRSKPGCSVNQYRGGGCYFGPDITNDILKKYNLSLLIRSHECKIDGYEWCHENKVVTLFSASNYYKQGSNKGAFLRIDNEHNKQFFQYTTHKKNQKHLTLIQSVNQIEESALRDLKGKILAFKNELAEEFIQKDVNNRGVIELQEWCTVMENVLKLPLPWRTLRPHLVKLSKEGKVEYSSIFEAQQVDNKFLMIAGTMT--EELYKNKENLETIFRIMDKDNSGHISLSEFRDACKLLHRHTNRNVSEEAIEDLAKCLDINKDGQIDFNEFLEAFRIVD 2076 +I+AAI IQ WYRR++A+ E +RR W I+Q++EY+ EQDQ +L FFNDL+ + +A + + + + VS D + + IV AK+ P+ N + LI+ FRK++ LH +Y+ +L LK PN+S ST++S++VT+CGDLHG+LDDL+ + +KN P +SNPY+ NGDFVDRG +E+ +L S +L +P +VFLNRGNHED VMN RYGF++E++ KY N +I+ F +++ WLPL +++++ +L+ HGG S +LD+I+ +DR K++S+L+ P+ D + +K EW QI D++WSDP++ GC N RG G +FGPD+T++ L+++ LS +IRSHECK +G+E+ H+NK++T+FSASNYY GSNKGA++R++N+ F QY + K L+ Q + +E SAL++L ++ ++EL +EF + D + G I + WC VMENV KL LPWR LR L + KV Y+ + D A M+ + LY NK +L IF I+D DNSG I+L EF A LL H S+ + + + +D+N DG++D NEFLEAFR+ D Sbjct: 90 TIRAAIFIQKWYRRHQARREMQRRCNWQIFQNLEYASEQDQAELYKFFNDLIK----------HMPQAAGRKNQYQGSAHVSVLDDKDDLVEEFGDIV------NAKIELPIRKNHIDLLIDVFRKKRGNRLHPKYVALILREAAKSLKQLPNISPVSTAVSQQVTVCGDLHGKLDDLLVVLHKNGLPSSSNPYVFNGDFVDRGKRGLEVLLLLLSLYLAFPNAVFLNRGNHEDSVMNARYGFIREVESKYPRNHKRILAFIDEVYRWLPLGSVLNSRVLIVHGGFSDSTSLDLIKSIDRGKYVSILRPPLTDGEPLDK-TEWQQIFDIMWSDPQATMGCVPNTLRGAGVWFGPDVTDNFLQRHRLSYVIRSHECKPNGHEFMHDNKIITIFSASNYYAIGSNKGAYIRLNNQLMPHFVQYISAASQTKRLSFKQRMGIVESSALKELAVRMRDHRDELEDEFRKYDPKDSGYISISHWCKVMENVTKLGLPWRLLRDKLAPGTDSQKVNYNRTLDLLDTDVILEAEADGMSVMDALYANKASLVAIFNIIDADNSGEITLDEFETAIDLLVAHMPGAYSKAEMLEKCRMMDLNGDGKVDLNEFLEAFRLSD 684
BLAST of Serine/threonine-protein phosphatase with EF-hands vs. Ensembl Fly
Match: rdgC (gene:FBgn0265959 transcript:FBtr0342947) HSP 1 Score: 514.998 bits (1325), Expect = 6.070e-173 Identity = 258/612 (42.16%), Postives = 387/612 (63.24%), Query Frame = 1 Query: 253 SIKAAILIQNWYRRYRAKLEAKRRYTWMIYQSIEYSGEQDQLKLQSFFNDLLSLTNKGQECDSEVIEALSKTHVLKTAPTVSDEDRDLQYLTKIEQIVVEPTYKGAKLTFPLSINQVTALIESFRKEQ--ILHARYLLELLDHTRNLLKTKPNVSQASTSISKRVTICGDLHGQLDDLVTIFYKNKFPDTSNPYIINGDFVDRGSHSVEIAAILFSFFLLYPQSVFLNRGNHEDHVMNYRYGFVKEIQIKYKSNANKIVRFFADIFSWLPLMTIIDNSILVCHGGISAMLNLDVIEKLDRHKFLSVLQAPVEDIKNENKEEEWMQILDLLWSDPRSKPGCSVNQYRGGGCYFGPDITNDILKKYNLSLLIRSHECKIDGYEWCHENKVVTLFSASNYYKQGSNKGAFLRIDNEHNKQFFQYTTHKKNQKHLTLIQSVNQIEESALRDLKGKILAFKNELAEEFIQKDVNNRGVIELQEWCTVMENVLKLPLPWRTLRPHLVKLSKEGKVEYSSIFEAQQVDNKFLMIAGTMT--EELYKNKENLETIFRIMDKDNSGHISLSEFRDACKLLHRHTNRNVSEEAIEDLAKCLDINKDGQIDFNEFLEAFRIVD 2076 +I+AAI IQ WYRR++A+ E +RR W I+Q++EY+ EQDQ +L FFNDL+ + +A + + + + VS D + + IV AK+ P+ N + LI+ FRK++ LH +Y+ +L LK PN+S ST++S++VT+CGDLHG+LDDL+ + +KN P +SNPY+ NGDFVDRG +E+ +L S +L +P +VFLNRGNHED VMN RYGF++E++ KY N +I+ F +++ WLPL +++++ +L+ HGG S +LD+I+ +DR K++S+L+ P+ D + +K EW QI D++WSDP++ GC N RG G +FGPD+T++ L+++ LS +IRSHECK +G+E+ H+NK++T+FSASNYY GSNKGA++R++N+ F QY + K L+ Q + +E SAL++L ++ ++EL +EF + D + G I + WC VMENV KL LPWR LR L + KV Y+ + D A M+ + LY NK +L IF I+D DNSG I+L EF A LL H S+ + + + +D+N DG++D NEFLEAFR+ D Sbjct: 90 TIRAAIFIQKWYRRHQARREMQRRCNWQIFQNLEYASEQDQAELYKFFNDLIK----------HMPQAAGRKNQYQGSAHVSVLDDKDDLVEEFGDIV------NAKIELPIRKNHIDLLIDVFRKKRGNRLHPKYVALILREAAKSLKQLPNISPVSTAVSQQVTVCGDLHGKLDDLLVVLHKNGLPSSSNPYVFNGDFVDRGKRGLEVLLLLLSLYLAFPNAVFLNRGNHEDSVMNARYGFIREVESKYPRNHKRILAFIDEVYRWLPLGSVLNSRVLIVHGGFSDSTSLDLIKSIDRGKYVSILRPPLTDGEPLDK-TEWQQIFDIMWSDPQATMGCVPNTLRGAGVWFGPDVTDNFLQRHRLSYVIRSHECKPNGHEFMHDNKIITIFSASNYYAIGSNKGAYIRLNNQLMPHFVQYISAASQTKRLSFKQRMGIVESSALKELAVRMRDHRDELEDEFRKYDPKDSGYISISHWCKVMENVTKLGLPWRLLRDKLAPGTDSQKVNYNRTLDLLDTDVILEAEADGMSVMDALYANKASLVAIFNIIDADNSGEITLDEFETAIDLLVAHMPGAYSKAEMLEKCRMMDLNGDGKVDLNEFLEAFRLSD 684
BLAST of Serine/threonine-protein phosphatase with EF-hands vs. Ensembl Fly
Match: rdgC (gene:FBgn0265959 transcript:FBtr0342948) HSP 1 Score: 514.998 bits (1325), Expect = 6.070e-173 Identity = 258/612 (42.16%), Postives = 387/612 (63.24%), Query Frame = 1 Query: 253 SIKAAILIQNWYRRYRAKLEAKRRYTWMIYQSIEYSGEQDQLKLQSFFNDLLSLTNKGQECDSEVIEALSKTHVLKTAPTVSDEDRDLQYLTKIEQIVVEPTYKGAKLTFPLSINQVTALIESFRKEQ--ILHARYLLELLDHTRNLLKTKPNVSQASTSISKRVTICGDLHGQLDDLVTIFYKNKFPDTSNPYIINGDFVDRGSHSVEIAAILFSFFLLYPQSVFLNRGNHEDHVMNYRYGFVKEIQIKYKSNANKIVRFFADIFSWLPLMTIIDNSILVCHGGISAMLNLDVIEKLDRHKFLSVLQAPVEDIKNENKEEEWMQILDLLWSDPRSKPGCSVNQYRGGGCYFGPDITNDILKKYNLSLLIRSHECKIDGYEWCHENKVVTLFSASNYYKQGSNKGAFLRIDNEHNKQFFQYTTHKKNQKHLTLIQSVNQIEESALRDLKGKILAFKNELAEEFIQKDVNNRGVIELQEWCTVMENVLKLPLPWRTLRPHLVKLSKEGKVEYSSIFEAQQVDNKFLMIAGTMT--EELYKNKENLETIFRIMDKDNSGHISLSEFRDACKLLHRHTNRNVSEEAIEDLAKCLDINKDGQIDFNEFLEAFRIVD 2076 +I+AAI IQ WYRR++A+ E +RR W I+Q++EY+ EQDQ +L FFNDL+ + +A + + + + VS D + + IV AK+ P+ N + LI+ FRK++ LH +Y+ +L LK PN+S ST++S++VT+CGDLHG+LDDL+ + +KN P +SNPY+ NGDFVDRG +E+ +L S +L +P +VFLNRGNHED VMN RYGF++E++ KY N +I+ F +++ WLPL +++++ +L+ HGG S +LD+I+ +DR K++S+L+ P+ D + +K EW QI D++WSDP++ GC N RG G +FGPD+T++ L+++ LS +IRSHECK +G+E+ H+NK++T+FSASNYY GSNKGA++R++N+ F QY + K L+ Q + +E SAL++L ++ ++EL +EF + D + G I + WC VMENV KL LPWR LR L + KV Y+ + D A M+ + LY NK +L IF I+D DNSG I+L EF A LL H S+ + + + +D+N DG++D NEFLEAFR+ D Sbjct: 90 TIRAAIFIQKWYRRHQARREMQRRCNWQIFQNLEYASEQDQAELYKFFNDLIK----------HMPQAAGRKNQYQGSAHVSVLDDKDDLVEEFGDIV------NAKIELPIRKNHIDLLIDVFRKKRGNRLHPKYVALILREAAKSLKQLPNISPVSTAVSQQVTVCGDLHGKLDDLLVVLHKNGLPSSSNPYVFNGDFVDRGKRGLEVLLLLLSLYLAFPNAVFLNRGNHEDSVMNARYGFIREVESKYPRNHKRILAFIDEVYRWLPLGSVLNSRVLIVHGGFSDSTSLDLIKSIDRGKYVSILRPPLTDGEPLDK-TEWQQIFDIMWSDPQATMGCVPNTLRGAGVWFGPDVTDNFLQRHRLSYVIRSHECKPNGHEFMHDNKIITIFSASNYYAIGSNKGAYIRLNNQLMPHFVQYISAASQTKRLSFKQRMGIVESSALKELAVRMRDHRDELEDEFRKYDPKDSGYISISHWCKVMENVTKLGLPWRLLRDKLAPGTDSQKVNYNRTLDLLDTDVILEAEADGMSVMDALYANKASLVAIFNIIDADNSGEITLDEFETAIDLLVAHMPGAYSKAEMLEKCRMMDLNGDGKVDLNEFLEAFRLSD 684
BLAST of Serine/threonine-protein phosphatase with EF-hands vs. Ensembl Zebrafish
Match: ppef1 (protein phosphatase, EF-hand calcium binding domain 1 [Source:ZFIN;Acc:ZDB-GENE-080303-27]) HSP 1 Score: 333.569 bits (854), Expect = 3.903e-103 Identity = 165/335 (49.25%), Postives = 222/335 (66.27%), Query Frame = 1 Query: 184 IENSKKTSHHVKKIYSTGDTGPISIKAAILIQNWYRRYRAKLEAKRRYTWMIYQSIEYSGEQDQLKLQSFFNDLL----SLTNKGQECDSEVIEALSKTHVLKTAPTVSDEDRDLQYLTKIEQIVVEPTYKGAKLTFPLSINQVTALIESFRKEQILHARYLLELLDHTRNLLKTKPNVSQASTSISKRVTICGDLHGQLDDLVTIFYKNKFPDTSNPYIINGDFVDRGSHSVEIAAILFSFFLLYPQSVFLNRGNHEDHVMNYRYGFVKEIQIKYKSNANKIVRFFADIFSWLPLMTIIDNSILVCHGGISAMLNLDVIEKLDRHKFLSVLQAP 1176 IEN + S I + ++IKAAILIQ WYRRY A LE +RRYTW I+QSIEY+GEQDQL+L SFF +L + G + S +++++ +++E R L+Y EQI+V +Y G +L+FPLS+ AL+ +F++EQ LH +Y+L+LL T+ LK PNV STS +K +TICGDLHG+LDDL+ IFYKN P NPYI NGDFVDRG S EI ILF+F LLYP + LNRGNHEDH+MN RYGF +E+ KYK++ +I++ D+FS LP+ T+IDN +L+ HGGIS +LD + ++RHK S L+ P Sbjct: 9 IENQTRPSETDGSIKQSNPA--LTIKAAILIQRWYRRYVAHLEMRRRYTWNIFQSIEYAGEQDQLQLSSFFTFMLDNFTQINGNGPDLISHLLDSV--------VDPLTEEVRQLKY----EQIMVPESYSGPRLSFPLSVTDTNALLSAFKEEQTLHGKYVLQLLYETKKFLKQMPNVIYLSTSYAKEITICGDLHGRLDDLLLIFYKNGLPSAENPYIFNGDFVDRGKKSTEIIIILFAFVLLYPDHMHLNRGNHEDHIMNLRYGFTREVMQKYKTHGREILQLLQDVFSLLPVATVIDNKVLIVHGGISDKTDLDFLSTVERHKVKSALRLP 329 HSP 2 Score: 320.857 bits (821), Expect = 2.394e-98 Identity = 150/291 (51.55%), Postives = 200/291 (68.73%), Query Frame = 1 Query: 1201 KEEEWMQILDLLWSDPRSKPGCSVNQYRGGGCYFGPDITNDILKKYNLSLLIRSHECKIDGYEWCHENKVVTLFSASNYYKQGSNKGAFLRIDNEHNKQFFQYTTHKKNQKHLTLIQSVNQIEESALRDLKGKILAFKNELAEEFIQKDVNNRGVIELQEWCTVMENVLKLPLPWRTLRPHLVKLSKEGKVEYSSIFEAQQVDNKFLMIAGTMTEELYKNKENLETIFRIMDKDNSGHISLSEFRDACKLLHRHTNRNVSEEAIEDLAKCLDINKDGQIDFNEFLEAFRIV 2073 +E EW Q++D+LWSDP+ + GCS N +RGGGCYFGPD+T +L+K+ L LLIRSHECK +GYE CH +V+T+FSASNYY++GSN+GA++++ E +FFQY + +K LTL Q V E SALR LK K+ A ++EL F Q D+NN G I EW V+E+VL+L LPWRTLRP L +L +G VEY S FE + + E LY+ + +LE IF I+DKD+SG IS+ EFR KL H V+++ I+D+A+ +D NKDG IDF EFLEAFR+V Sbjct: 429 EELEWQQVVDILWSDPKHQNGCSPNSFRGGGCYFGPDVTQTLLQKHGLCLLIRSHECKQEGYELCHNGQVITIFSASNYYEEGSNRGAYVKLGPELVPRFFQYQVSRSTRK-LTLHQRVRVAEGSALRALKEKLYAHRSELMAAFQQYDINNTGRISTSEWAQVVESVLRLDLPWRTLRPRLARLGTDGNVEYESCFEDISPGEPIPPVTPNLAETLYRYRTDLEIIFNIIDKDHSGQISIEEFRQTWKLFSSHLGVAVNDQTIDDMARSIDFNKDGSIDFTEFLEAFRVV 718
BLAST of Serine/threonine-protein phosphatase with EF-hands vs. Ensembl Zebrafish
Match: ppef1 (protein phosphatase, EF-hand calcium binding domain 1 [Source:ZFIN;Acc:ZDB-GENE-080303-27]) HSP 1 Score: 332.028 bits (850), Expect = 9.192e-103 Identity = 160/312 (51.28%), Postives = 214/312 (68.59%), Query Frame = 1 Query: 253 SIKAAILIQNWYRRYRAKLEAKRRYTWMIYQSIEYSGEQDQLKLQSFFNDLL----SLTNKGQECDSEVIEALSKTHVLKTAPTVSDEDRDLQYLTKIEQIVVEPTYKGAKLTFPLSINQVTALIESFRKEQILHARYLLELLDHTRNLLKTKPNVSQASTSISKRVTICGDLHGQLDDLVTIFYKNKFPDTSNPYIINGDFVDRGSHSVEIAAILFSFFLLYPQSVFLNRGNHEDHVMNYRYGFVKEIQIKYKSNANKIVRFFADIFSWLPLMTIIDNSILVCHGGISAMLNLDVIEKLDRHKFLSVLQAP 1176 +IKAAILIQ WYRRY A LE +RRYTW I+QSIEY+GEQDQL+L SFF +L + G + S +++++ +++E R L+Y EQI+V +Y G +L+FPLS+ AL+ +F++EQ LH +Y+L+LL T+ LK PNV STS +K +TICGDLHG+LDDL+ IFYKN P NPYI NGDFVDRG S EI ILF+F LLYP + LNRGNHEDH+MN RYGF +E+ KYK++ +I++ D+FS LP+ T+IDN +L+ HGGIS +LD + ++RHK S L+ P Sbjct: 19 AIKAAILIQRWYRRYVAHLEMRRRYTWNIFQSIEYAGEQDQLQLSSFFTFMLDNFTQINGNGPDLISHLLDSV--------VDPLTEEVRQLKY----EQIMVPESYSGPRLSFPLSVTDTNALLSAFKEEQTLHGKYVLQLLYETKKFLKQMPNVIYLSTSYAKEITICGDLHGRLDDLLLIFYKNGLPSAENPYIFNGDFVDRGKKSTEIIIILFAFVLLYPDHMHLNRGNHEDHIMNLRYGFTREVMQKYKTHGREILQLLQDVFSLLPVATVIDNKVLIVHGGISDKTDLDFLSTVERHKVKSALRLP 318 HSP 2 Score: 320.472 bits (820), Expect = 2.139e-98 Identity = 150/291 (51.55%), Postives = 200/291 (68.73%), Query Frame = 1 Query: 1201 KEEEWMQILDLLWSDPRSKPGCSVNQYRGGGCYFGPDITNDILKKYNLSLLIRSHECKIDGYEWCHENKVVTLFSASNYYKQGSNKGAFLRIDNEHNKQFFQYTTHKKNQKHLTLIQSVNQIEESALRDLKGKILAFKNELAEEFIQKDVNNRGVIELQEWCTVMENVLKLPLPWRTLRPHLVKLSKEGKVEYSSIFEAQQVDNKFLMIAGTMTEELYKNKENLETIFRIMDKDNSGHISLSEFRDACKLLHRHTNRNVSEEAIEDLAKCLDINKDGQIDFNEFLEAFRIV 2073 +E EW Q++D+LWSDP+ + GCS N +RGGGCYFGPD+T +L+K+ L LLIRSHECK +GYE CH +V+T+FSASNYY++GSN+GA++++ E +FFQY + +K LTL Q V E SALR LK K+ A ++EL F Q D+NN G I EW V+E+VL+L LPWRTLRP L +L +G VEY S FE + + E LY+ + +LE IF I+DKD+SG IS+ EFR KL H V+++ I+D+A+ +D NKDG IDF EFLEAFR+V Sbjct: 418 EELEWQQVVDILWSDPKHQNGCSPNSFRGGGCYFGPDVTQTLLQKHGLCLLIRSHECKQEGYELCHNGQVITIFSASNYYEEGSNRGAYVKLGPELVPRFFQYQVSRSTRK-LTLHQRVRVAEGSALRALKEKLYAHRSELMAAFQQYDINNTGRISTSEWAQVVESVLRLDLPWRTLRPRLARLGTDGNVEYESCFEDISPGEPIPPVTPNLAETLYRYRTDLEIIFNIIDKDHSGQISIEEFRQTWKLFSSHLGVAVNDQTIDDMARSIDFNKDGSIDFTEFLEAFRVV 707
BLAST of Serine/threonine-protein phosphatase with EF-hands vs. Ensembl Zebrafish
Match: ppef1 (protein phosphatase, EF-hand calcium binding domain 1 [Source:ZFIN;Acc:ZDB-GENE-080303-27]) HSP 1 Score: 332.028 bits (850), Expect = 9.192e-103 Identity = 160/312 (51.28%), Postives = 214/312 (68.59%), Query Frame = 1 Query: 253 SIKAAILIQNWYRRYRAKLEAKRRYTWMIYQSIEYSGEQDQLKLQSFFNDLL----SLTNKGQECDSEVIEALSKTHVLKTAPTVSDEDRDLQYLTKIEQIVVEPTYKGAKLTFPLSINQVTALIESFRKEQILHARYLLELLDHTRNLLKTKPNVSQASTSISKRVTICGDLHGQLDDLVTIFYKNKFPDTSNPYIINGDFVDRGSHSVEIAAILFSFFLLYPQSVFLNRGNHEDHVMNYRYGFVKEIQIKYKSNANKIVRFFADIFSWLPLMTIIDNSILVCHGGISAMLNLDVIEKLDRHKFLSVLQAP 1176 +IKAAILIQ WYRRY A LE +RRYTW I+QSIEY+GEQDQL+L SFF +L + G + S +++++ +++E R L+Y EQI+V +Y G +L+FPLS+ AL+ +F++EQ LH +Y+L+LL T+ LK PNV STS +K +TICGDLHG+LDDL+ IFYKN P NPYI NGDFVDRG S EI ILF+F LLYP + LNRGNHEDH+MN RYGF +E+ KYK++ +I++ D+FS LP+ T+IDN +L+ HGGIS +LD + ++RHK S L+ P Sbjct: 19 AIKAAILIQRWYRRYVAHLEMRRRYTWNIFQSIEYAGEQDQLQLSSFFTFMLDNFTQINGNGPDLISHLLDSV--------VDPLTEEVRQLKY----EQIMVPESYSGPRLSFPLSVTDTNALLSAFKEEQTLHGKYVLQLLYETKKFLKQMPNVIYLSTSYAKEITICGDLHGRLDDLLLIFYKNGLPSAENPYIFNGDFVDRGKKSTEIIIILFAFVLLYPDHMHLNRGNHEDHIMNLRYGFTREVMQKYKTHGREILQLLQDVFSLLPVATVIDNKVLIVHGGISDKTDLDFLSTVERHKVKSALRLP 318 HSP 2 Score: 320.472 bits (820), Expect = 2.139e-98 Identity = 150/291 (51.55%), Postives = 200/291 (68.73%), Query Frame = 1 Query: 1201 KEEEWMQILDLLWSDPRSKPGCSVNQYRGGGCYFGPDITNDILKKYNLSLLIRSHECKIDGYEWCHENKVVTLFSASNYYKQGSNKGAFLRIDNEHNKQFFQYTTHKKNQKHLTLIQSVNQIEESALRDLKGKILAFKNELAEEFIQKDVNNRGVIELQEWCTVMENVLKLPLPWRTLRPHLVKLSKEGKVEYSSIFEAQQVDNKFLMIAGTMTEELYKNKENLETIFRIMDKDNSGHISLSEFRDACKLLHRHTNRNVSEEAIEDLAKCLDINKDGQIDFNEFLEAFRIV 2073 +E EW Q++D+LWSDP+ + GCS N +RGGGCYFGPD+T +L+K+ L LLIRSHECK +GYE CH +V+T+FSASNYY++GSN+GA++++ E +FFQY + +K LTL Q V E SALR LK K+ A ++EL F Q D+NN G I EW V+E+VL+L LPWRTLRP L +L +G VEY S FE + + E LY+ + +LE IF I+DKD+SG IS+ EFR KL H V+++ I+D+A+ +D NKDG IDF EFLEAFR+V Sbjct: 418 EELEWQQVVDILWSDPKHQNGCSPNSFRGGGCYFGPDVTQTLLQKHGLCLLIRSHECKQEGYELCHNGQVITIFSASNYYEEGSNRGAYVKLGPELVPRFFQYQVSRSTRK-LTLHQRVRVAEGSALRALKEKLYAHRSELMAAFQQYDINNTGRISTSEWAQVVESVLRLDLPWRTLRPRLARLGTDGNVEYESCFEDISPGEPIPPVTPNLAETLYRYRTDLEIIFNIIDKDHSGQISIEEFRQTWKLFSSHLGVAVNDQTIDDMARSIDFNKDGSIDFTEFLEAFRVV 707
BLAST of Serine/threonine-protein phosphatase with EF-hands vs. Ensembl Zebrafish
Match: CU695117.1 (protein phosphatase with EF-hand domain 2a [Source:NCBI gene;Acc:100537120]) HSP 1 Score: 284.263 bits (726), Expect = 1.912e-84 Identity = 144/298 (48.32%), Postives = 191/298 (64.09%), Query Frame = 1 Query: 1195 ENKEEEWMQILDLLWSDPRSKPGCSVNQYRGGGCYFGPDITNDILKKYNLSLLIRSHECKIDGYEWCHENKVVTLFSASNYYKQGSNKGAFLRIDNEHNKQFFQYTTHKKNQKHLTLIQSVNQIEESALRDLKGKILAFKNELAEEFIQKDVNNRGVIELQEWCTVMENVLKLPLPWRTLRPHLVKLSKEGKVEYSSIF--EAQQVDNKFLMIAGTMTEELYKNKENLETIFRIMDKDNSGHISLSEFRDACKLLHRHTNRNVSEEAIEDLAKCLDINKDGQIDFNEFLEAFRIVDSS 2082 + +EW QILDLLWSDP S+ GC N+ RGGGCY+GP+IT D L ++NL L+IRSHECK DGYE+CH KVVTLFSASNYY+ GSN+GAF+R+ + F QY + L+ Q+V + E +AL+ L+ K+ A K++L F + D N G+I L +W +E VL L LPWR L P LV + G + Y F A + N +I +M E LY+++ LETIFRI+D DNSG IS +FR KLL + +S+E I +L +D N DG ID +EF+EAFR+VD S Sbjct: 382 DTSNDEWKQILDLLWSDPMSQDGCVPNEVRGGGCYWGPNITEDFLNRHNLQLIIRSHECKQDGYEFCHNRKVVTLFSASNYYEIGSNRGAFVRLGPDLMPYFIQYQATSMT-RGLSFPQNVKRTEHTALKVLREKLFAHKSDLLSAFQELDKENTGLISLSDWARAVERVLHLDLPWRILHPQLVSSTTNGMLNYHGWFCDLALKKPNS-EVIEQSMLETLYRHRSTLETIFRIVDTDNSGLISFEDFRQTLKLLSAYLKMEISDEVINELVVSMDTNNDGSIDIDEFMEAFRLVDKS 677 HSP 2 Score: 280.411 bits (716), Expect = 4.590e-83 Identity = 135/291 (46.39%), Postives = 193/291 (66.32%), Query Frame = 1 Query: 307 LEAKRRYTWMIYQSIEYSGEQDQLKLQSFFNDLL-SLTNKGQECDSEVIEALSKTHVLKTAPTVSDEDRDLQYLTKIEQIVVEPTYKGAKLTFPLSINQVTALIESFRKEQILHARYLLELLDHTRNLLKTKPNVSQASTSISKRVTICGDLHGQLDDLVTIFYKNKFPDTSNPYIINGDFVDRGSHSVEIAAILFSFFLLYPQSVFLNRGNHEDHVMNYRYGFVKEIQIKYKSNANKIVRFFADIFSWLPLMTIIDNSILVCHGGISAMLNLDVIEKLDRHKFLSVLQAP 1176 +E +RRYTW I+QS+EY+ QDQ+KL +F L+ + T E +I +H+ + D + + + I V Y G +LTFPL ++Q L+E+F+ +Q LH+RY+L+LL T LL+ PN+++ ST SK +TICGDLHGQL+DL+ IFYKN P PY+ NGD+VDRG S+E+ ILF+F L+YP V+LNRGNHEDH++N RYGF KE+ KYK + +I++ IFSWLPL+T+ID +L+ HGGIS NL +I ++DRH+++S L+ P Sbjct: 1 MEMRRRYTWNIFQSMEYADLQDQIKLYNFLGYLVDNFTPSSSE--RNLI-----SHIFRENEVCRDAEWERYF--NYTNIDVPDIYSGPRLTFPLDMDQAADLVEAFKNKQQLHSRYVLQLLLETWKLLRVLPNINRVSTCHSKEITICGDLHGQLEDLLLIFYKNGMPSMEKPYVFNGDYVDRGKDSMEVLLILFAFLLVYPGDVYLNRGNHEDHIINLRYGFTKEVLGKYKLHGKRILKLLQKIFSWLPLVTVIDQRVLIVHGGISDSTNLALIARVDRHRYVSALRPP 282
BLAST of Serine/threonine-protein phosphatase with EF-hands vs. Ensembl Zebrafish
Match: ppp5c (protein phosphatase 5, catalytic subunit [Source:ZFIN;Acc:ZDB-GENE-050327-75]) HSP 1 Score: 240.35 bits (612), Expect = 9.448e-71 Identity = 134/350 (38.29%), Postives = 202/350 (57.71%), Query Frame = 1 Query: 532 IEQIVVEPTYKGAKL-TFPLSINQVTALIESFRKEQILHARYLLELLDHTRNLLKTKPNVSQASTSISKRVTICGDLHGQLDDLVTIFYKNKFPDTSNPYIINGDFVDRGSHSVEIAAILFSFFLLYPQSVFLNRGNHEDHVMNYRYGFVKEIQIKYKSNANKIVRFFADIFSWLPLMTIIDNSILVCHGGISA--MLNLDVIEKLDRHKFLSVLQAPVEDIKNENKEEEWMQILDLLWSDPRSKPGCSVNQYRGGGCYFGPDITNDILKKYNLSLLIRSHECKIDGYEWCHENKVVTLFSASNYYKQGSNKGAFLRIDNEHNK-QFFQYTT-HKKNQKHLTLIQSVNQI 1566 IE + +E Y G KL +++ + L++ F+ ++ LH + ++L + +L P++ + + S+++TICGD HGQ DL+ IF N P +NPY+ NGDFVDRGS SVE+ LF F LLYP+ L RGNHE MN YGF E++ KY S ++ + F+++F WLPL I++ +LV HGG+ + + LD I K+DR++ Q P + + DLLWSDP+ + G S+++ RG C FGPD+T L++ L ++RSHE K +GYE H K +T+FSA NY Q NKGA++ + K +F Q+T N K + S+ Q+ Sbjct: 157 IENMTIEDDYAGPKLEDGKVTLKFMEDLMDWFKDQKKLHRKCAYQILVQVKEVLTKLPSLVEITLKESEKITICGDTHGQYYDLLNIFELNSLPSPTNPYLFNGDFVDRGSFSVEVILTLFGFKLLYPEHFHLLRGNHETDNMNQMYGFEGEVKAKYSS---QMFKLFSEVFQWLPLAQCINDKVLVMHGGLFSEDGVTLDDIRKIDRNR-----QPP-----------DSGPMCDLLWSDPQLQNGRSISK-RGVSCQFGPDVTERFLEQNKLEYIVRSHEVKAEGYEVTHSGKCITVFSAPNYCDQMGNKGAYIHLRGSDLKPEFHQFTAVPHPNVKPMAYANSLMQM 486
BLAST of Serine/threonine-protein phosphatase with EF-hands vs. Ensembl Xenopus
Match: usp43 (ubiquitin specific peptidase 43 [Source:Xenbase;Acc:XB-GENE-940625]) HSP 1 Score: 314.694 bits (805), Expect = 1.818e-96 Identity = 148/289 (51.21%), Postives = 200/289 (69.20%), Query Frame = 1 Query: 1207 EEWMQILDLLWSDPRSKPGCSVNQYRGGGCYFGPDITNDILKKYNLSLLIRSHECKIDGYEWCHENKVVTLFSASNYYKQGSNKGAFLRIDNEHNKQFFQYTTHKKNQKHLTLIQSVNQIEESALRDLKGKILAFKNELAEEFIQKDVNNRGVIELQEWCTVMENVLKLPLPWRTLRPHLVKLSKEGKVEYSSIFEAQQVDNKFLMIAGTMTEELYKNKENLETIFRIMDKDNSGHISLSEFRDACKLLHRHTNRNVSEEAIEDLAKCLDINKDGQIDFNEFLEAFRIV 2073 +EW Q++D+LWSDPR++ GC+ N +RGGGCYFGP++T +L KYN +LIRSHECK +GYE CH KVVT+FSASNYY +GSN+GA+L++ + +F Y K +K LTL Q V+ +E++ALR L+ KI A ++EL F D G I + EW + +E VL L LPWRTLRP L+KL+ +G V+Y S FE Q++ + + E +Y+ K +LE IF I+DKD+SG IS+ EFR KL H + N+ + AI+DLA +D NKDG IDFNEFLEAFR+V Sbjct: 366 KEWKQVVDILWSDPRNQNGCTPNSFRGGGCYFGPNVTKKLLAKYNFKMLIRSHECKQEGYELCHNGKVVTIFSASNYYDEGSNRGAYLKLSPDLTPRFVPYQVSKCTRK-LTLHQRVSAVEDTALRALREKIYAHRSELINAFKLCDPKETGKISISEWASAVEAVLHLDLPWRTLRPRLIKLTSDGSVDYLSSFEDLQIEQPIKEVQPNLVETIYRYKADLEIIFNIIDKDHSGLISVEEFRQTWKLFSSHLHINIDDSAIDDLAHSIDTNKDGSIDFNEFLEAFRVV 653 HSP 2 Score: 256.144 bits (653), Expect = 1.354e-74 Identity = 132/312 (42.31%), Postives = 185/312 (59.29%), Query Frame = 1 Query: 250 ISIKAAILIQNWYRRYRAKLEAKRRYTWMIYQSIEYSGEQDQLKLQSFFNDLLSLTNKGQECDSEVIEALSKTHVLKTAPTVSDEDRDLQYLTKIEQIVVEPTYKGAKLTFPLSINQVTALIESFRKEQILHARYLLELLDHTRNLLKTKPNVSQASTSISKRVTICGDLHGQLDDLVTIFYKNKFPDTSNPYIINGDFVDRGSHSVEIAAILFSFFLLYPQSVFLNRGNHEDHVMNYRYGFVKEIQIKYKSNANKIVRFFADIFSWLPLMTIIDNSILVCHGGISAMLNLDVIEKLDRHKFLSVLQAPVED 1185 ++IKAAILIQ WYR Y A+LE +RRYT I+QSIEY+ EQ QL+L +FF ++ + ++I +S + ++ E+I V +Y G ++TFPL+++ AL+ +F++ Q LHARY+L+L T+ LK PN+ STS SK +TICGDLHG+LDDL+ IFYKN P T N Y+ NGD VDRG +S+EI +LF+F L+YP +V +NRGNHED +MN S LPL TI+D+ +L+ HGGI +LD + +DR K+ S L+ P D Sbjct: 17 LAIKAAILIQRWYRFYTARLEMRRRYTLNIFQSIEYAEEQAQLQLSNFFTFMMDHFAHWKGQGPDLISDISNS-------------KEGHKFIDYEKIEVPNSYGGPRITFPLTVSDTNALLRAFKQGQQLHARYVLQLFHETKKFLKQLPNIVHLSTSYSKEITICGDLHGKLDDLLLIFYKNGLPSTENHYLFNGDLVDRGKNSIEILVLLFTFLLMYPNNVHINRGNHEDPIMN---------------------------LSRLPLATIVDSKVLILHGGIGDKTDLDFLSSIDRFKYKSALRTPKTD 288
BLAST of Serine/threonine-protein phosphatase with EF-hands vs. Ensembl Xenopus
Match: PPEF2 (protein phosphatase, EF-hand calcium binding domain 2 [Source:NCBI gene;Acc:100496073]) HSP 1 Score: 296.59 bits (758), Expect = 2.460e-89 Identity = 150/292 (51.37%), Postives = 195/292 (66.78%), Query Frame = 1 Query: 1204 EEEWMQILDLLWSDPRSKPGCSVNQYRGGGCYFGPDITNDILKKYNLSLLIRSHECKIDGYEWCHENKVVTLFSASNYYKQGSNKGAFLRIDNEHNKQFFQYTTHKKNQKHLTLIQSVNQIEESALRDLKGKILAFKNELAEEFIQKDVNNRGVIELQEWCTVMENVLKLPLPWRTLRPHLVKLSKEGKVEYSSIFEAQQVDNKFL-MIAGTMTEELYKNKENLETIFRIMDKDNSGHISLSEFRDACKLLHRHTNRNVSEEAIEDLAKCLDINKDGQIDFNEFLEAFRIVD 2076 +EE QI+D+LWSDP + GC N RGGGCYFGPD+T IL+K+ L +LIRSHECK +GYE+CH KV+T+FSASNYY+ GSNKGAF+++ + F QY + +LTL Q V+ +EESALR L+ K+ A K++L F D N G I L +W V+E+VL L LPWR LRP L+ S EG + Y F+ V + ++ E LY+N+ +LETIFRI+D D+SG IS EF+ KLL H N VS+EAI +A+ +D NKDG ID NEFLEAFR+VD Sbjct: 405 DEEKKQIVDILWSDPIPQDGCKSNTVRGGGCYFGPDVTEKILQKHGLQMLIRSHECKQEGYEFCHSGKVLTIFSASNYYEVGSNKGAFVKLGPDLVPHFVQYQASRLTN-NLTLRQRVSTVEESALRALREKLFAHKSDLMNAFRNYDNNQTGYINLSDWAIVLESVLNLGLPWRMLRPQLIHSSPEGLLRYREWFDELSVCQPIQEHLHDSLLEALYRNRSDLETIFRIIDSDSSGLISFEEFQHTWKLLSSHLNIEVSDEAICKMARSIDFNKDGNIDINEFLEAFRLVD 695 HSP 2 Score: 288.115 bits (736), Expect = 4.173e-86 Identity = 141/299 (47.16%), Postives = 192/299 (64.21%), Query Frame = 1 Query: 304 KLEAKRRYTWMIYQSIEYSGEQDQLKLQSFFNDLLS-LTNKGQECDSEVIEALSKTHVLKTAPTVSDEDRDLQYLTKIEQIVVEPTYKGAKLTFPLSINQVTALIESFRKEQILHARYLLELLDHTRNLLKTKPNVSQASTSISKRVTICGDLHGQLDDLVTIFYKNKFPDTSNPYIINGDFVDRGSHSVEIAAILFSFFLLYPQSVFLNRGNHEDHVMNYRYGFVKEIQIKYKSNANKIVRFFADIFSWLPLMTIIDNSILVCHGGISAMLNLDVIEKLDRHKFLSVLQAPVEDIKNE 1197 ++E +RR TW I+QSIEY+GEQDQ+KL FFN L+ T + + ++ K D +L+ E I V +Y G L+FP+ TAL+E+F++ Q LH+RY+L LL T+ LK PN+ + STS K +TICGDLHG+LDDL IFYKN P PYI NGDFVDRG S+EI ILF+F L+YP+ V LNRGNHED+++N RYGF KE+ KYK + KI++ +FSWLPL T+ID +LV HGG+S +L+++ K++RHKF S L+ + KN+ Sbjct: 1 QMEVRRRCTWSIFQSIEYTGEQDQIKLYDFFNLLMDHFTPDNSKERDFICRIFTEEENFK--------DTELEKYCDYETIEVPESYTGPHLSFPIKPTHATALVEAFKQNQQLHSRYVLHLLHETKKYLKQLPNIKRISTSYGKEITICGDLHGRLDDLFLIFYKNGLPSPEKPYIFNGDFVDRGKQSIEILMILFAFQLVYPKVVHLNRGNHEDYIVNLRYGFTKEVMKKYKVHGKKILKMLQSVFSWLPLATLIDQKVLVTHGGVSDTTDLEILSKIERHKFASTLRPHKKKEKNK 291
BLAST of Serine/threonine-protein phosphatase with EF-hands vs. Ensembl Xenopus
Match: ppp5c (protein phosphatase 5, catalytic subunit [Source:NCBI gene;Acc:493275]) HSP 1 Score: 235.343 bits (599), Expect = 1.970e-68 Identity = 132/364 (36.26%), Postives = 202/364 (55.49%), Query Frame = 1 Query: 421 KGQECDSEVIEALSKTHVLKTAPTVSDEDRDLQYLTKIEQIVVEPTYKGAKLT-FPLSINQVTALIESFRKEQILHARYLLELLDHTRNLLKTKPNVSQASTSISKRVTICGDLHGQLDDLVTIFYKNKFPDTSNPYIINGDFVDRGSHSVEIAAILFSFFLLYPQSVFLNRGNHEDHVMNYRYGFVKEIQIKYKSNANKIVRFFADIFSWLPLMTIIDNSILVCHGGISA--MLNLDVIEKLDRHKFLSVLQAPVEDIKNENKEEEWMQILDLLWSDPRSKPGCSVNQYRGGGCYFGPDITNDILKKYNLSLLIRSHECKIDGYEWCHENKVVTLFSASNYYKQGSNKGAFLRIDNEHNKQFF 1503 K QEC L + + A +R + IE + +E Y G +L ++I+ + L++ ++ ++ LH + + ++L +++L P++ + S S++VT+CGD HGQ DL+ IF+ N P +NPYI NGDFVDRGS SVE+ LF F LLYP L RGNHE MN YGF E++ KY + ++ + F+++F WLPL ++ +L+ HGG+ + + LD I ++R++ Q P + + DLLWSDP+ + G S ++ RG C FGPD+T L++ L +IRSHE K +GYE H VT+FSA NY Q NKGA++ ++ K F Sbjct: 147 KFQECSK-----LVRQKAFERAIACEQHNRSVVDSLDIEGMTIEDEYTGPQLKDGNVTIDFMLELMQFYKDQKKLHRKCVYQMLVQVKDILSKLPSLVEISLEKSQQVTVCGDTHGQFYDLMNIFHLNGLPSENNPYIFNGDFVDRGSFSVEVIVTLFGFKLLYPAHFHLLRGNHETDTMNQMYGFEGEVKAKYSA---QMFQLFSEVFQWLPLAMCVNQRVLIMHGGLFSEDGVTLDQIRSIERNR-----QPP-----------DSGPMCDLLWSDPQPQDGRSSSK-RGVSCQFGPDVTRRFLEENGLDYIIRSHEVKPEGYEVSHNGLCVTVFSAPNYCDQMGNKGAYIHLNGSDLKPKF 485
BLAST of Serine/threonine-protein phosphatase with EF-hands vs. Ensembl Xenopus
Match: ppp5c (protein phosphatase 5, catalytic subunit [Source:NCBI gene;Acc:493275]) HSP 1 Score: 221.861 bits (564), Expect = 1.626e-63 Identity = 128/364 (35.16%), Postives = 195/364 (53.57%), Query Frame = 1 Query: 421 KGQECDSEVIEALSKTHVLKTAPTVSDEDRDLQYLTKIEQIVVEPTYKGAKLT-FPLSINQVTALIESFRKEQILHARYLLELLDHTRNLLKTKPNVSQASTSISKRVTICGDLHGQLDDLVTIFYKNKFPDTSNPYIINGDFVDRGSHSVEIAAILFSFFLLYPQSVFLNRGNHEDHVMNYRYGFVKEIQIKYKSNANKIVRFFADIFSWLPLMTIIDNSILVCHGGISA--MLNLDVIEKLDRHKFLSVLQAPVEDIKNENKEEEWMQILDLLWSDPRSKPGCSVNQYRGGGCYFGPDITNDILKKYNLSLLIRSHECKIDGYEWCHENKVVTLFSASNYYKQGSNKGAFLRIDNEHNKQFF 1503 K QEC L + + A +R + IE + +E Y G +L ++I+ + L++ ++ ++ LH + + ++L +++L P++ + S S++VT+CGD HGQ DL+ IF+ N P +NPYI NGDFVDRGS SVE+ LF F LLYP L RGNHE MN YGF E++ KY + ++ + F+++F WLPL ++ +L+ HGG+ + + LD I ++R++ Q P + I +SD RS + RG C FGPD+T L++ L +IRSHE K +GYE H VT+FSA NY Q NKGA++ ++ K F Sbjct: 147 KFQECSK-----LVRQKAFERAIACEQHNRSVVDSLDIEGMTIEDEYTGPQLKDGNVTIDFMLELMQFYKDQKKLHRKCVYQMLVQVKDILSKLPSLVEISLEKSQQVTVCGDTHGQFYDLMNIFHLNGLPSENNPYIFNGDFVDRGSFSVEVIVTLFGFKLLYPAHFHLLRGNHETDTMNQMYGFEGEVKAKYSA---QMFQLFSEVFQWLPLAMCVNQRVLIMHGGLFSEDGVTLDQIRSIERNR-----QPPDSGVTLVLLLLLSFPI----FSDGRS------SSKRGVSCQFGPDVTRRFLEENGLDYIIRSHEVKPEGYEVSHNGLCVTVFSAPNYCDQMGNKGAYIHLNGSDLKPKF 487
BLAST of Serine/threonine-protein phosphatase with EF-hands vs. Ensembl Xenopus
Match: ppp5c (protein phosphatase 5, catalytic subunit [Source:NCBI gene;Acc:493275]) HSP 1 Score: 208.379 bits (529), Expect = 7.709e-59 Identity = 128/365 (35.07%), Postives = 189/365 (51.78%), Query Frame = 1 Query: 421 KGQECDSEVIEALSKTHVLKTAPTVSDEDRDLQYLTKIEQIVVEPTYKGAKLT-FPLSINQVTALIESFRKEQILHARYLLELLDHTRNLLKTKPNVSQASTSISKRVTICGDLHGQLDDLVTIFYKNKFPDTSNPYIINGDFVDRGSHSVEIAAILFSFFLLYPQSVFLNRGNHEDHVMNYRYGFVKEIQIKYKSNANKIVRFFADIFSWLPLMTIIDNSILVCHGGISA--MLNLDVIEKLDRHKFLSVLQAPVEDIKNENKEEEWMQILDLLWSDPRSKPGCSVNQYRGGGCYFGPDITNDILKKYNLSLLIRSHECKIDGYEWCHENKVVTLFSASNYYKQGSNKGAFLRIDNEHNKQFFQ 1506 K QEC L + + A +R + IE + +E Y G +L ++I+ + L++ ++ ++ LH + V Q +S + +CGD HGQ DL+ IF+ N P +NPYI NGDFVDRGS SVE+ LF F LLYP L RGNHE MN YGF E++ KY + ++ + F+++F WLPL ++ +L+ HGG+ + + LD I ++R++ Q P + + DLLWSDP+ + G S ++ RG C FGPD+T L++ L +IRSHE K +GYE H VT+FSA NY Q NKGA++ ++ K F Sbjct: 130 KFQECSK-----LVRQKAFERAIACEQHNRSVVDSLDIEGMTIEDEYTGPQLKDGNVTIDFMLELMQFYKDQKKLH-----------------RKCVYQVRFCLS--LYMCGDTHGQFYDLMNIFHLNGLPSENNPYIFNGDFVDRGSFSVEVIVTLFGFKLLYPAHFHLLRGNHETDTMNQMYGFEGEVKAKYSA---QMFQLFSEVFQWLPLAMCVNQRVLIMHGGLFSEDGVTLDQIRSIERNR-----QPP-----------DSGPMCDLLWSDPQPQDGRSSSK-RGVSCQFGPDVTRRFLEENGLDYIIRSHEVKPEGYEVSHNGLCVTVFSAPNYCDQMGNKGAYIHLNGSDLKPKFH 450
BLAST of Serine/threonine-protein phosphatase with EF-hands vs. Ensembl Mouse
Match: Ppef1 (protein phosphatase with EF hand calcium-binding domain 1 [Source:MGI Symbol;Acc:MGI:1097157]) HSP 1 Score: 546.969 bits (1408), Expect = 0.000e+0 Identity = 294/636 (46.23%), Postives = 401/636 (63.05%), Query Frame = 1 Query: 256 IKAAILIQNWYRRYRAKLEAKRRYTWMIYQSIEYSGEQDQLKLQSFFNDLLSLTNKGQECDSEVIEALSKTHVLKTAPTVSD-EDRDLQYLTKIEQIVVEPTYKGAKLTFPLSINQVTALIESFRKEQILHARYLLELLDHTRNLLKTKPNVSQASTSISKRVTICGDLHGQLDDLVTIFYKNKFPDTSNPYIINGDFVDRGSHSVEIAAILFSFFLLYPQSVFLNRGNHEDHVMNYRYGFVKEIQIKYKSNANKIVRFFADIFSWLPLMTIIDNSILVCHGGISAMLNLDVIEKLDRHKFLSVLQAPV----EDIKNENK----------------------EEEWMQILDLLWSDPRSKPGCSVNQYRGGGCYFGPDITNDILKKYNLSLLIRSHECKIDGYEWCHENKVVTLFSASNYYKQGSNKGAFLRIDNEHNKQFFQY---TTHKKNQKHLTLIQSVNQIEESALRDLKGKILAFKNELAEEFIQKDVNNRGVIELQEWCTVMENVLKLPLPWRTLRPHLVKLSKEGKVEYSSIFEAQQVDNKFLMIAGTMTEELYKNKENLETIFRIMDKDNSGHISLSEFRDACKLLHRHTNRNVSEEAIEDLAKCLDINKDGQIDFNEFLEAFRIV 2073 IKAA++IQNWYRRYRA+L ++ Y I+QSIEYS EQ Q++L SFF+ +L K DS ++ T + S +DRD +L IE V +Y G +L FPL+ + L+++F+++QILHA Y+LE+L R +LK PN S T +K +TICGDLHG+LDDL+ IFYKN P +NPY+ NGDFVDRG++S+EI IL FL+YP + LNRGNHED +MN RYGF KEI KYK + KI++ ++++WLP+ TIIDN ILV HGGIS +L+ + +L R+K SVL PV E + NK ++EW QI+D+LWSDPR K GC N RGGGCYFGPD+T+ +L K L +LIRSHECK DGYE H+ KV+T+FSASNYY++GSN+GA++R+ QFFQY +T N H Q +N +E SA + LK K+++ K +L F +D + G I L EW MEN+L L LPWR+L HLV + G V+Y S F+ +++ + +TE +Y+ + +L+ IF I+D D SG IS+ EFR KL + H ++ + I++LA +D NKDG IDFNEFL+AF +V Sbjct: 17 IKAALVIQNWYRRYRARLRVRQHYALAIFQSIEYSDEQGQMQLSSFFSFMLENYTKTNNEDSALV-----TRIFDNTRRESQIKDRD-DFLGLIE---VPDSYDGPRLQFPLTFTDIHILLQAFKQQQILHAHYVLEVLFEARKVLKQMPNFSHVKTFPAKEITICGDLHGKLDDLMLIFYKNGLPSENNPYVFNGDFVDRGNNSMEILMILLVCFLVYPSDLHLNRGNHEDFMMNLRYGFTKEILQKYKLHGRKILQVLEEVYTWLPIGTIIDNEILVIHGGISESTDLNTLHQLQRNKMKSVLMPPVLGNQETGEKRNKSASNYVEPRKVEPDKTPSEDLTKQEWEQIVDILWSDPRGKKGCYPNTSRGGGCYFGPDVTSKVLSKNQLKMLIRSHECKPDGYEVSHDGKVITVFSASNYYEEGSNRGAYIRLSYGTMPQFFQYQVTSTSCLNPLH----QRMNAMESSAFKILKEKMISRKTDLINAFELRDHSRSGRISLAEWAFSMENILGLNLPWRSLSSHLVTIDSSGSVDYMSSFDDIRIEKPTKDMKSNLTETMYRYRSDLKIIFNIIDSDQSGLISMDEFRTMWKLFNAHYKAHIDDSQIDELASIVDFNKDGNIDFNEFLKAFYVV 639
BLAST of Serine/threonine-protein phosphatase with EF-hands vs. Ensembl Mouse
Match: Ppef2 (protein phosphatase, EF hand calcium-binding domain 2 [Source:MGI Symbol;Acc:MGI:1342304]) HSP 1 Score: 313.153 bits (801), Expect = 4.141e-95 Identity = 151/320 (47.19%), Postives = 207/320 (64.69%), Query Frame = 1 Query: 253 SIKAAILIQNWYRRYRAKLEAKRRYTWMIYQSIEYSGEQDQLKLQSFFNDLLSLTNKGQECDSEVIEALSKTHVLKTAPTVSDEDRDLQYLTKIEQIVVEPTYKGAKLTFPLSINQVTALIESFRKEQILHARYLLELLDHTRNLLKTKPNVSQASTSISKRVTICGDLHGQLDDLVTIFYKNKFPDTSNPYIINGDFVDRGSHSVEIAAILFSFFLLYPQSVFLNRGNHEDHVMNYRYGFVKEIQIKYKSNANKIVRFFADIFSWLPLMTIIDNSILVCHGGISAMLNLDVIEKLDRHKFLSVLQAPVEDIKNENKEEE 1212 + KAA LIQ WYRRY A+LE +RR TW I+QSIEY+G+QDQ+KL FF+ L+ + + + + +D + + E I V +Y G +L+FPL + TAL+E+FR Q LHARY+L LL TR L PN+++ ST S+ VT+CGDLHGQLDDL+ IFYKN P Y+ NGDFVDRG SVE+ +LF+F L+YP+ LNRGNHEDH++N RYGF KE+ KYK + KI+R D+F WLPL T++D +LV HGG+S +L+++ KLDRHK +S ++ ++EN+EE+ Sbjct: 19 AFKAAALIQRWYRRYMARLEMRRRCTWNIFQSIEYAGQQDQVKLHEFFSYLVDHFTPSSHHERDFLNRMFTEERFA-------QDVETEEGGDFESIEVPDSYTGPRLSFPLLPDHATALVEAFRLRQQLHARYVLNLLYETRKHLAQLPNINRVSTCYSEEVTVCGDLHGQLDDLIFIFYKNGLPSPERAYVFNGDFVDRGKDSVEVLMVLFAFMLVYPKEFHLNRGNHEDHLVNLRYGFTKEVMHKYKIHGKKILRTLQDVFCWLPLATLVDEKVLVLHGGVSDKTDLELLAKLDRHKIVSTMRCKTRK-ESENREEQ 330 HSP 2 Score: 308.145 bits (788), Expect = 2.711e-93 Identity = 147/299 (49.16%), Postives = 207/299 (69.23%), Query Frame = 1 Query: 1195 ENKEEEWMQILDLLWSDPRSKPGCSVNQYRGGGCYFGPDITNDILKKYNLSLLIRSHECKIDGYEWCHENKVVTLFSASNYYKQGSNKGAFLRIDNEHNKQFFQYTTHKKNQKHLTLIQSVNQIEESALRDLKGKILAFKNELAEEFIQKDVNNRGVIELQEWCTVMENVLKLPLPWRTLRPHLVKLSKEGKVEYSSIFEA---QQVDNKFLMIAGTMTEELYKNKENLETIFRIMDKDNSGHISLSEFRDACKLLHRHTNRNVSEEAIEDLAKCLDINKDGQIDFNEFLEAFRIVDSS 2082 E EEW Q++D+LWSDP ++ GC N RGGGCYFGPD+T +++KY L LLIRSHECK +GYE+CH KV+T+FSASNYY+ GSN+GA++++ QY +K + LT+ Q ++++EESALR L+ K+ A ++L EF ++D + GVI L +W T +E+VL L LPWR LRP LV S + +EY S ++ +Q+ + I ++ E+LY+N+ NLETIFRI+D D+SG ISL EFR KL H + +++++ I DLA+ +D NKDG ID NEFLEAFR+V+ S Sbjct: 436 EPTPEEWKQVVDILWSDPAAQEGCKANAVRGGGCYFGPDVTERLMEKYKLQLLIRSHECKPEGYEFCHNRKVLTIFSASNYYEVGSNRGAYVKLGPALTPHIVQYQANKATHR-LTMRQRISRVEESALRALRQKLFAHSSDLLVEFRKRDPDESGVITLSDWATAVESVLHLGLPWRMLRPQLVNSSADNVLEYRSWLDSLAKEQLSRE--NIQSSLLEKLYRNRSNLETIFRIIDSDHSGFISLDEFRQTWKLFSSHMSIDITDDGICDLARSIDFNKDGHIDINEFLEAFRLVEQS 731
BLAST of Serine/threonine-protein phosphatase with EF-hands vs. Ensembl Mouse
Match: Ppef2 (protein phosphatase, EF hand calcium-binding domain 2 [Source:MGI Symbol;Acc:MGI:1342304]) HSP 1 Score: 313.153 bits (801), Expect = 4.141e-95 Identity = 151/320 (47.19%), Postives = 207/320 (64.69%), Query Frame = 1 Query: 253 SIKAAILIQNWYRRYRAKLEAKRRYTWMIYQSIEYSGEQDQLKLQSFFNDLLSLTNKGQECDSEVIEALSKTHVLKTAPTVSDEDRDLQYLTKIEQIVVEPTYKGAKLTFPLSINQVTALIESFRKEQILHARYLLELLDHTRNLLKTKPNVSQASTSISKRVTICGDLHGQLDDLVTIFYKNKFPDTSNPYIINGDFVDRGSHSVEIAAILFSFFLLYPQSVFLNRGNHEDHVMNYRYGFVKEIQIKYKSNANKIVRFFADIFSWLPLMTIIDNSILVCHGGISAMLNLDVIEKLDRHKFLSVLQAPVEDIKNENKEEE 1212 + KAA LIQ WYRRY A+LE +RR TW I+QSIEY+G+QDQ+KL FF+ L+ + + + + +D + + E I V +Y G +L+FPL + TAL+E+FR Q LHARY+L LL TR L PN+++ ST S+ VT+CGDLHGQLDDL+ IFYKN P Y+ NGDFVDRG SVE+ +LF+F L+YP+ LNRGNHEDH++N RYGF KE+ KYK + KI+R D+F WLPL T++D +LV HGG+S +L+++ KLDRHK +S ++ ++EN+EE+ Sbjct: 19 AFKAAALIQRWYRRYMARLEMRRRCTWNIFQSIEYAGQQDQVKLHEFFSYLVDHFTPSSHHERDFLNRMFTEERFA-------QDVETEEGGDFESIEVPDSYTGPRLSFPLLPDHATALVEAFRLRQQLHARYVLNLLYETRKHLAQLPNINRVSTCYSEEVTVCGDLHGQLDDLIFIFYKNGLPSPERAYVFNGDFVDRGKDSVEVLMVLFAFMLVYPKEFHLNRGNHEDHLVNLRYGFTKEVMHKYKIHGKKILRTLQDVFCWLPLATLVDEKVLVLHGGVSDKTDLELLAKLDRHKIVSTMRCKTRK-ESENREEQ 330 HSP 2 Score: 308.145 bits (788), Expect = 2.711e-93 Identity = 147/299 (49.16%), Postives = 207/299 (69.23%), Query Frame = 1 Query: 1195 ENKEEEWMQILDLLWSDPRSKPGCSVNQYRGGGCYFGPDITNDILKKYNLSLLIRSHECKIDGYEWCHENKVVTLFSASNYYKQGSNKGAFLRIDNEHNKQFFQYTTHKKNQKHLTLIQSVNQIEESALRDLKGKILAFKNELAEEFIQKDVNNRGVIELQEWCTVMENVLKLPLPWRTLRPHLVKLSKEGKVEYSSIFEA---QQVDNKFLMIAGTMTEELYKNKENLETIFRIMDKDNSGHISLSEFRDACKLLHRHTNRNVSEEAIEDLAKCLDINKDGQIDFNEFLEAFRIVDSS 2082 E EEW Q++D+LWSDP ++ GC N RGGGCYFGPD+T +++KY L LLIRSHECK +GYE+CH KV+T+FSASNYY+ GSN+GA++++ QY +K + LT+ Q ++++EESALR L+ K+ A ++L EF ++D + GVI L +W T +E+VL L LPWR LRP LV S + +EY S ++ +Q+ + I ++ E+LY+N+ NLETIFRI+D D+SG ISL EFR KL H + +++++ I DLA+ +D NKDG ID NEFLEAFR+V+ S Sbjct: 436 EPTPEEWKQVVDILWSDPAAQEGCKANAVRGGGCYFGPDVTERLMEKYKLQLLIRSHECKPEGYEFCHNRKVLTIFSASNYYEVGSNRGAYVKLGPALTPHIVQYQANKATHR-LTMRQRISRVEESALRALRQKLFAHSSDLLVEFRKRDPDESGVITLSDWATAVESVLHLGLPWRMLRPQLVNSSADNVLEYRSWLDSLAKEQLSRE--NIQSSLLEKLYRNRSNLETIFRIIDSDHSGFISLDEFRQTWKLFSSHMSIDITDDGICDLARSIDFNKDGHIDINEFLEAFRLVEQS 731
BLAST of Serine/threonine-protein phosphatase with EF-hands vs. Ensembl Mouse
Match: Ppef1 (protein phosphatase with EF hand calcium-binding domain 1 [Source:MGI Symbol;Acc:MGI:1097157]) HSP 1 Score: 226.868 bits (577), Expect = 7.952e-69 Identity = 109/212 (51.42%), Postives = 148/212 (69.81%), Query Frame = 1 Query: 502 EDRDLQYLTKIEQIVVEPTYKGAKLTFPLSINQVTALIESFRKEQILHARYLLELLDHTRNLLKTKPNVSQASTSISKRVTICGDLHGQLDDLVTIFYKNKFPDTSNPYIINGDFVDRGSHSVEIAAILFSFFLLYPQSVFLNRGNHEDHVMNYRYGFVKEIQIKYKSNANKIVRFFADIFSWLPLMTIIDNSILVCHGGISAMLNLDVIEK 1137 +DRD +L IE V +Y G +L FPL+ + L+++F+++QILHA Y+LE+L R +LK PN S T +K +TICGDLHG+LDDL+ IFYKN P +NPY+ NGDFVDRG++S+EI IL FL+YP + LNRGNHED +MN RYGF KEI KYK + KI++ ++++WLP+ TIIDN ILV HGGIS +L+ + + Sbjct: 30 KDRD-DFLGLIE---VPDSYDGPRLQFPLTFTDIHILLQAFKQQQILHAHYVLEVLFEARKVLKQMPNFSHVKTFPAKEITICGDLHGKLDDLMLIFYKNGLPSENNPYVFNGDFVDRGNNSMEILMILLVCFLVYPSDLHLNRGNHEDFMMNLRYGFTKEILQKYKLHGRKILQVLEEVYTWLPIGTIIDNEILVIHGGISESTDLNTLHQ 237
BLAST of Serine/threonine-protein phosphatase with EF-hands vs. Ensembl Mouse
Match: Ppp5c (protein phosphatase 5, catalytic subunit [Source:MGI Symbol;Acc:MGI:102666]) HSP 1 Score: 228.024 bits (580), Expect = 6.364e-66 Identity = 125/332 (37.65%), Postives = 190/332 (57.23%), Query Frame = 1 Query: 532 IEQIVVEPTYKGAKLT-FPLSINQVTALIESFRKEQILHARYLLELLDHTRNLLKTKPNVSQASTSISKRVTICGDLHGQLDDLVTIFYKNKFPDTSNPYIINGDFVDRGSHSVEIAAILFSFFLLYPQSVFLNRGNHEDHVMNYRYGFVKEIQIKYKSNANKIVRFFADIFSWLPLMTIIDNSILVCHGGISA--MLNLDVIEKLDRHKFLSVLQAPVEDIKNENKEEEWMQILDLLWSDPRSKPGCSVNQYRGGGCYFGPDITNDILKKYNLSLLIRSHECKIDGYEWCHENKVVTLFSASNYYKQGSNKGAFLRID-NEHNKQFFQYTT 1515 IE + +E Y G KL ++I + L++ ++ ++ LH + ++L + +L + + + ++++T+CGD HGQ DL+ IF N P +NPYI NGDFVDRGS SVE+ LF F LLYP L RGNHE MN YGF E++ KY + ++ F+++F WLPL I+ +L+ HGG+ + + LD I K++R++ Q P + + DLLWSDP+ + G SV++ RG C FGPD+T L++ L +IRSHE K +GYE H + VT+FSA NY Q NK +++ + ++ QF Q+T Sbjct: 167 IESMTIEDEYSGPKLEDGKVTITFMKDLMQWYKDQKKLHRKCAYQILVQVKEVLCKLSTLVETTLKETEKITVCGDTHGQFYDLLNIFELNGLPSETNPYIFNGDFVDRGSFSVEVILTLFGFKLLYPDHFHLLRGNHETDNMNQIYGFEGEVKAKYTA---QMYELFSEVFEWLPLAQCINGKVLIMHGGLFSEDGVTLDDIRKIERNR-----QPP-----------DSGPMCDLLWSDPQPQNGRSVSK-RGVSCQFGPDVTKAFLEENQLDYIIRSHEVKAEGYEVAHGGRCVTVFSAPNYCDQMGNKASYIHLQGSDLRPQFHQFTA 478
BLAST of Serine/threonine-protein phosphatase with EF-hands vs. UniProt/SwissProt
Match: sp|G5EBX9|PPE_CAEEL (Serine/threonine-protein phosphatase with EF-hands pef-1 OS=Caenorhabditis elegans OX=6239 GN=pef-1 PE=1 SV=1) HSP 1 Score: 568.926 bits (1465), Expect = 0.000e+0 Identity = 285/636 (44.81%), Postives = 401/636 (63.05%), Query Frame = 1 Query: 250 ISIKAAILIQNWYRRYRAKLEAKRRYTWMIYQSIEYSGEQDQLKLQSFFNDLLSL----TNKG---QECDSEVIEALSKTHVLKTAPTVSDED----RDLQYLTKIEQIVVEPTYKGAKLTFPLSINQVTALIESFRKEQILHARYLLELLDHTRNLLKTKPNVSQASTSISKRVTICGDLHGQLDDLVTIFYKNKFPDTSNPYIINGDFVDRGSHSVEIAAILFSFFLLYPQSVFLNRGNHEDHVMNYRYGFVKEIQIKYKSNANKIVRFFADIFSWLPLMTIIDNSILVCHGGISAMLNLDVIEKLDRHKFLSVLQAPVEDIKNENKE------EEWMQILDLLWSDPRSKPGCSVNQYRGGGCYFGPDITNDILKKYNLSLLIRSHECKIDGYEWCHENKVVTLFSASNYYKQGSNKGAFLR-IDNEHNKQFFQYTTHKKNQKHLTLIQSVNQIEESALRDLKGKILAFKNELAEEFIQKDVNNRGVIELQEWCTVMENVLKLPLPWRTLRPHLVKLSKEGKVEYSSIFEAQQVDNKFLMIAGT------MTEELYKNKENLETIFRIMDKDNSGHISLSEFRDACKLLHRHTNRNVSEEAIEDLAKCLDINKDGQIDFNEFLEAFRIVDSSL 2085 ++IK+AILIQ WYRR A+LEA+RR TW I+ ++EY+GEQDQLKL FF D++ KG +S ++ ALS H K P++ D + + + T + ++ YKG L+ PL QV +IE+F+ ++LH +Y+L +L R + K P+VS+ STSIS +VTICGDLHG+ DDL I YKN +P NPYI NGDFVDRG S+E+ +LF+ ++ P S++LNRGNHEDH+MN RYGF+KE+ KYK + I R D+FSWLP+ TIID I V HGGIS + ++K+ RH+F SVL+ PV KE +EW Q+LD++WSDP+ GC N +RGGG YFG DIT L+K+ LL+RSHECK +GYE+ H N +T+FSASNYY+ GSN+GA+++ I F QY K ++K TL + + +EESA+++LK K+ +F +L +EF D+ G + + +W +E + L LPW L P + LS++GK + + D + + GT + E LY++K LET+FR MDKDNSG +S+ EF DAC++L ++T R + + I +A+ +D NKDG ID NE LEAFR+VD L Sbjct: 81 LTIKSAILIQKWYRRCEARLEARRRATWQIFTALEYAGEQDQLKLYDFFADVIRAMAEENGKGGVENGRNSPLMSALS--HYAK--PSLMDSEGETVKKMLEDTSPTNVDIDRNYKGPTLSLPLDKPQVAKMIEAFKVNKVLHPKYVLMILHEARKIFKAMPSVSRISTSISNQVTICGDLHGKFDDLCIILYKNGYPSVDNPYIFNGDFVDRGGQSIEVLCVLFALVIVDPMSIYLNRGNHEDHIMNLRYGFIKELSTKYKDLSTPITRLLEDVFSWLPIATIIDRDIFVVHGGISDQTEVSKLDKIPRHRFQSVLRPPVNKGMESEKENSAVNVDEWKQMLDIMWSDPKQNKGCWPNVFRGGGSYFGADITASFLEKHGFRLLVRSHECKFEGYEFSHNNTCLTVFSASNYYETGSNRGAYVKFIGKSKQPHFVQYMASKTHRKS-TLRERLGVVEESAVKELKEKLSSFHTDLQKEFEIMDIEKSGKLPILKWSDCVERITGLNLPWIALAPKVATLSEDGK------YVMYKEDRRIAQVGGTHAQEKDIVESLYRHKSTLETLFRFMDKDNSGQVSMKEFIDACEVLGKYTKRPLQTDYISQIAESIDFNKDGFIDLNELLEAFRLVDRPL 705
BLAST of Serine/threonine-protein phosphatase with EF-hands vs. UniProt/SwissProt
Match: sp|Q3SWT6|PPE1_RAT (Serine/threonine-protein phosphatase with EF-hands 1 OS=Rattus norvegicus OX=10116 GN=Ppef1 PE=2 SV=1) HSP 1 Score: 562.762 bits (1449), Expect = 0.000e+0 Identity = 282/623 (45.26%), Postives = 401/623 (64.37%), Query Frame = 1 Query: 256 IKAAILIQNWYRRYRAKLEAKRRYTWMIYQSIEYSGEQDQLKLQSFFNDLLSLTNKGQECDSEVIEALSKTHVLKTAPTVSDEDRDLQYLTKIEQIVVEPTYKGAKLTFPLSINQVTALIESFRKEQILHARYLLELLDHTRNLLKTKPNVSQASTSISKRVTICGDLHGQLDDLVTIFYKNKFPDTSNPYIINGDFVDRGSHSVEIAAILFSFFLLYPQSVFLNRGNHEDHVMNYRYGFVKEIQIKYKSNANKIVRFFADIFSWLPLMTIIDNSILVCHGGISAMLNLDVIEKLDRHKFLSVLQAPVEDIKNENKEE-----------------EWMQILDLLWSDPRSKPGCSVNQYRGGGCYFGPDITNDILKKYNLSLLIRSHECKIDGYEWCHENKVVTLFSASNYYKQGSNKGAFLRIDNEHNKQFFQYTTHKKNQKHLTLIQSVNQIEESALRDLKGKILAFKNELAEEFIQKDVNNRGVIELQEWCTVMENVLKLPLPWRTLRPHLVKLSKEGKVEYSSIFEAQQVDNKFLMIAGTMTEELYKNKENLETIFRIMDKDNSGHISLSEFRDACKLLHRHTNRNVSEEAIEDLAKCLDINKDGQIDFNEFLEAFRIV 2073 ++AA++IQNWYRRYRA+L A++ Y I+QSIEY+ EQ Q++L SFF+ +L + DS ++ L + L++ +DR+ +Y+ I+ V +Y G +L FPL+ + L+++F+++Q LHA Y+LE+L R +LK PN ++ T +K +TICGDLHG+LDDL+ IFYKN P NPY+ NGDFVDRG++S+EI IL FL+YP + LNRGNHED +MN RYGF KEI KYK + KI++ ++++WLP+ TIIDN ILV HGGIS +L+++++L R+K SVL P+ + N ++ EW QI+DLLWSDPR K GC N RGGGCYFGPD+T+ +L K L ++IRSHECK DGYE CH+ KV+T+FSASNYY++GSN+GA++R+ + QFFQY + + L Q VN +E SA R LK +++A K +L F +D + G I L +W ME++L L LPWR+L HLV G V+Y S F+ ++ + + E +Y+ + +L+ IF I+D D SG IS+ EFR KL + H ++ + I++LA +D NKDG IDFNEFL AF +V Sbjct: 17 VRAALIIQNWYRRYRARLSARQHYALAIFQSIEYADEQGQMQLSSFFSFMLENYTNTHKEDSALVSRLFENTRLES------KDRE-EYVGLID---VPDSYDGPRLQFPLTFTDINLLLQAFKQQQTLHAHYVLEVLFEARKILKQMPNFTRIQTFPAKEITICGDLHGKLDDLMLIFYKNGLPSEKNPYVFNGDFVDRGNNSMEILMILLVSFLVYPTDLHLNRGNHEDFMMNLRYGFTKEILQKYKLHGKKILQVLEELYTWLPIGTIIDNEILVIHGGISESTDLNILQQLQRNKMKSVLMPPMSTNQECNIKKNKAGPSEQSASEQLTKLEWEQIIDLLWSDPRGKKGCYPNTSRGGGCYFGPDVTSKVLNKNQLKMVIRSHECKPDGYEICHDGKVITVFSASNYYEEGSNRGAYIRLSYGTSPQFFQYQVTSTSCLN-PLYQRVNAMEFSAFRILKERMIARKTDLINAFELRDHSRTGKISLAQWAFSMESILGLNLPWRSLSSHLVSTDSSGSVDYMSSFDDIHIEKPMKDMKSDLIETMYRYRSDLKIIFNIIDTDQSGLISMDEFRTMWKLFNAHYKVHIDDSQIDELASTMDSNKDGNIDFNEFLRAFYVV 628
BLAST of Serine/threonine-protein phosphatase with EF-hands vs. UniProt/SwissProt
Match: sp|O14829|PPE1_HUMAN (Serine/threonine-protein phosphatase with EF-hands 1 OS=Homo sapiens OX=9606 GN=PPEF1 PE=1 SV=1) HSP 1 Score: 551.206 bits (1419), Expect = 0.000e+0 Identity = 279/641 (43.53%), Postives = 401/641 (62.56%), Query Frame = 1 Query: 253 SIKAAILIQNWYRRYRAKLEAKRRYTWMIYQSIEYSGEQDQLKLQSFFNDLLSLTNKGQECDSEVIEALSKTHV------LKTAPTVSDEDRDLQYLTKIEQIVVEPTYKGAKLTFPLSINQVTALIESFRKEQILHARYLLELLDHTRNLLKTKPNVSQASTSISKRVTICGDLHGQLDDLVTIFYKNKFPDTSNPYIINGDFVDRGSHSVEIAAILFSFFLLYPQSVFLNRGNHEDHVMNYRYGFVKEIQIKYKSNANKIVRFFADIFSWLPLMTIIDNSILVCHGGISAMLNLDVIEKLDRHKFLSVLQAPVEDIKNEN----------------------------KEEEWMQILDLLWSDPRSKPGCSVNQYRGGGCYFGPDITNDILKKYNLSLLIRSHECKIDGYEWCHENKVVTLFSASNYYKQGSNKGAFLRIDNEHNKQFFQYTTHKKNQKHLTLIQSVNQIEESALRDLKGKILAFKNELAEEFIQKDVNNRGVIELQEWCTVMENVLKLPLPWRTLRPHLVKLSKEGKVEYSSIFEAQQVDNKFLMIAGTMTEELYKNKENLETIFRIMDKDNSGHISLSEFRDACKLLHRHTNRNVSEEAIEDLAKCLDINKDGQIDFNEFLEAFRIV 2073 S++AA++IQNWYR Y+A+L+A++ Y I+QSIEY+ EQ Q++L +FF+ +L + TH+ L+ S++D ++ ++ I V +Y G +L FPL+ + L+E+F+++QILHA Y+LE+L T+ +LK PN + TS SK VTICGDLHG+LDDL IFYKN P NPY+ NGDFVDRG +S+EI IL FL+YP + LNRGNHED +MN RYGF KEI KYK + +I++ + ++WLP+ TI+DN ILV HGGIS +L+++ +++R+K SVL P E ++ + E EW QI+D+LWSDPR K GC N RGGGCYFGPD+T+ IL KY L +LIRSHECK +GYE CH+ KVVT+FSASNYY++GSN+GA++++ + +FFQY K L Q V+ +E SA++ L+ ++++ K++L F +D G + + +W MEN+L L LPWR+L +LV + + G VEY S F+ +++ T+ E LY+ + +LE IF +D D+SG IS+ EFR KL H N ++ + + LA +D+NKDG IDFNEFL+AF +V Sbjct: 16 SLRAALIIQNWYRGYKARLKARQHYALTIFQSIEYADEQGQMQLSTFFSFMLE----------------NYTHIHKEELELRNQSLESEQDMRDRW-DYVDSIDVPDSYNGPRLQFPLTCTDIDLLLEAFKEQQILHAHYVLEVLFETKKVLKQMPNFTHIQTSPSKEVTICGDLHGKLDDLFLIFYKNGLPSERNPYVFNGDFVDRGKNSIEILMILCVSFLVYPNDLHLNRGNHEDFMMNLRYGFTKEILHKYKLHGKRILQILEEFYAWLPIGTIVDNEILVIHGGISETTDLNLLHRVERNKMKSVLIPPTETNRDHDTDSKHNKVGVTFNAHGRIKTNGSPTEHLTEHEWEQIIDILWSDPRGKNGCFPNTCRGGGCYFGPDVTSKILNKYQLKMLIRSHECKPEGYEICHDGKVVTIFSASNYYEEGSNRGAYIKLCSGTTPRFFQYQVTKATCFQ-PLRQRVDTMENSAIKILRERVISRKSDLTRAFQLQDHRKSGKLSVSQWAFCMENILGLNLPWRSLSSNLVNIDQNGNVEYMSSFQNIRIEKPVQEAHSTLVETLYRYRSDLEIIFNAIDTDHSGLISVEEFRAMWKLFSSHYNVHIDDSQVNKLANIMDLNKDGSIDFNEFLKAFYVV 638
BLAST of Serine/threonine-protein phosphatase with EF-hands vs. UniProt/SwissProt
Match: sp|O35655|PPE1_MOUSE (Serine/threonine-protein phosphatase with EF-hands 1 OS=Mus musculus OX=10090 GN=Ppef1 PE=2 SV=2) HSP 1 Score: 546.969 bits (1408), Expect = 0.000e+0 Identity = 294/636 (46.23%), Postives = 401/636 (63.05%), Query Frame = 1 Query: 256 IKAAILIQNWYRRYRAKLEAKRRYTWMIYQSIEYSGEQDQLKLQSFFNDLLSLTNKGQECDSEVIEALSKTHVLKTAPTVSD-EDRDLQYLTKIEQIVVEPTYKGAKLTFPLSINQVTALIESFRKEQILHARYLLELLDHTRNLLKTKPNVSQASTSISKRVTICGDLHGQLDDLVTIFYKNKFPDTSNPYIINGDFVDRGSHSVEIAAILFSFFLLYPQSVFLNRGNHEDHVMNYRYGFVKEIQIKYKSNANKIVRFFADIFSWLPLMTIIDNSILVCHGGISAMLNLDVIEKLDRHKFLSVLQAPV----EDIKNENK----------------------EEEWMQILDLLWSDPRSKPGCSVNQYRGGGCYFGPDITNDILKKYNLSLLIRSHECKIDGYEWCHENKVVTLFSASNYYKQGSNKGAFLRIDNEHNKQFFQY---TTHKKNQKHLTLIQSVNQIEESALRDLKGKILAFKNELAEEFIQKDVNNRGVIELQEWCTVMENVLKLPLPWRTLRPHLVKLSKEGKVEYSSIFEAQQVDNKFLMIAGTMTEELYKNKENLETIFRIMDKDNSGHISLSEFRDACKLLHRHTNRNVSEEAIEDLAKCLDINKDGQIDFNEFLEAFRIV 2073 IKAA++IQNWYRRYRA+L ++ Y I+QSIEYS EQ Q++L SFF+ +L K DS ++ T + S +DRD +L IE V +Y G +L FPL+ + L+++F+++QILHA Y+LE+L R +LK PN S T +K +TICGDLHG+LDDL+ IFYKN P +NPY+ NGDFVDRG++S+EI IL FL+YP + LNRGNHED +MN RYGF KEI KYK + KI++ ++++WLP+ TIIDN ILV HGGIS +L+ + +L R+K SVL PV E + NK ++EW QI+D+LWSDPR K GC N RGGGCYFGPD+T+ +L K L +LIRSHECK DGYE H+ KV+T+FSASNYY++GSN+GA++R+ QFFQY +T N H Q +N +E SA + LK K+++ K +L F +D + G I L EW MEN+L L LPWR+L HLV + G V+Y S F+ +++ + +TE +Y+ + +L+ IF I+D D SG IS+ EFR KL + H ++ + I++LA +D NKDG IDFNEFL+AF +V Sbjct: 17 IKAALVIQNWYRRYRARLRVRQHYALAIFQSIEYSDEQGQMQLSSFFSFMLENYTKTNNEDSALV-----TRIFDNTRRESQIKDRD-DFLGLIE---VPDSYDGPRLQFPLTFTDIHILLQAFKQQQILHAHYVLEVLFEARKVLKQMPNFSHVKTFPAKEITICGDLHGKLDDLMLIFYKNGLPSENNPYVFNGDFVDRGNNSMEILMILLVCFLVYPSDLHLNRGNHEDFMMNLRYGFTKEILQKYKLHGRKILQVLEEVYTWLPIGTIIDNEILVIHGGISESTDLNTLHQLQRNKMKSVLMPPVLGNQETGEKRNKSASNYVEPRKVEPDKTPSEDLTKQEWEQIVDILWSDPRGKKGCYPNTSRGGGCYFGPDVTSKVLSKNQLKMLIRSHECKPDGYEVSHDGKVITVFSASNYYEEGSNRGAYIRLSYGTMPQFFQYQVTSTSCLNPLH----QRMNAMESSAFKILKEKMISRKTDLINAFELRDHSRSGRISLAEWAFSMENILGLNLPWRSLSSHLVTIDSSGSVDYMSSFDDIRIEKPTKDMKSNLTETMYRYRSDLKIIFNIIDSDQSGLISMDEFRTMWKLFNAHYKAHIDDSQIDELASIVDFNKDGNIDFNEFLKAFYVV 639
BLAST of Serine/threonine-protein phosphatase with EF-hands vs. UniProt/SwissProt
Match: sp|P40421|RDGC_DROME (Serine/threonine-protein phosphatase rdgC OS=Drosophila melanogaster OX=7227 GN=rdgC PE=2 SV=1) HSP 1 Score: 514.612 bits (1324), Expect = 6.479e-173 Identity = 258/612 (42.16%), Postives = 387/612 (63.24%), Query Frame = 1 Query: 253 SIKAAILIQNWYRRYRAKLEAKRRYTWMIYQSIEYSGEQDQLKLQSFFNDLLSLTNKGQECDSEVIEALSKTHVLKTAPTVSDEDRDLQYLTKIEQIVVEPTYKGAKLTFPLSINQVTALIESFRKEQ--ILHARYLLELLDHTRNLLKTKPNVSQASTSISKRVTICGDLHGQLDDLVTIFYKNKFPDTSNPYIINGDFVDRGSHSVEIAAILFSFFLLYPQSVFLNRGNHEDHVMNYRYGFVKEIQIKYKSNANKIVRFFADIFSWLPLMTIIDNSILVCHGGISAMLNLDVIEKLDRHKFLSVLQAPVEDIKNENKEEEWMQILDLLWSDPRSKPGCSVNQYRGGGCYFGPDITNDILKKYNLSLLIRSHECKIDGYEWCHENKVVTLFSASNYYKQGSNKGAFLRIDNEHNKQFFQYTTHKKNQKHLTLIQSVNQIEESALRDLKGKILAFKNELAEEFIQKDVNNRGVIELQEWCTVMENVLKLPLPWRTLRPHLVKLSKEGKVEYSSIFEAQQVDNKFLMIAGTMT--EELYKNKENLETIFRIMDKDNSGHISLSEFRDACKLLHRHTNRNVSEEAIEDLAKCLDINKDGQIDFNEFLEAFRIVD 2076 +I+AAI IQ WYRR++A+ E +RR W I+Q++EY+ EQDQ +L FFNDL+ + +A + + + + VS D + + IV AK+ P+ N + LI+ FRK++ LH +Y+ +L LK PN+S ST++S++VT+CGDLHG+LDDL+ + +KN P +SNPY+ NGDFVDRG +E+ +L S +L +P +VFLNRGNHED VMN RYGF++E++ KY N +I+ F +++ WLPL +++++ +L+ HGG S +LD+I+ +DR K++S+L+ P+ D + +K EW QI D++WSDP++ GC N RG G +FGPD+T++ L+++ LS +IRSHECK +G+E+ H+NK++T+FSASNYY GSNKGA++R++N+ F QY + K L+ Q + +E SAL++L ++ ++EL +EF + D + G I + WC VMENV KL LPWR LR L + KV Y+ + D A M+ + LY NK +L IF I+D DNSG I+L EF A LL H S+ + + + +D+N DG++D NEFLEAFR+ D Sbjct: 5 AIRAAIFIQKWYRRHQARREMQRRCNWQIFQNLEYASEQDQAELYKFFNDLIK----------HMPQAAGRKNQYQGSAHVSVLDDKDDLVEEFGDIV------NAKIELPIRKNHIDLLIDVFRKKRGNRLHPKYVALILREAAKSLKQLPNISPVSTAVSQQVTVCGDLHGKLDDLLVVLHKNGLPSSSNPYVFNGDFVDRGKRGLEVLLLLLSLYLAFPNAVFLNRGNHEDSVMNARYGFIREVESKYPRNHKRILAFIDEVYRWLPLGSVLNSRVLIVHGGFSDSTSLDLIKSIDRGKYVSILRPPLTDGEPLDK-TEWQQIFDIMWSDPQATMGCVPNTLRGAGVWFGPDVTDNFLQRHRLSYVIRSHECKPNGHEFMHDNKIITIFSASNYYAIGSNKGAYIRLNNQLMPHFVQYISAASQTKRLSFKQRMGIVESSALKELAVRMRDHRDELEDEFRKYDPKDSGYISISHWCKVMENVTKLGLPWRLLRDKLAPGTDSQKVNYNRTLDLLDTDVILEAEADGMSVMDALYANKASLVAIFNIIDADNSGEITLDEFETAIDLLVAHMPGAYSKAEMLEKCRMMDLNGDGKVDLNEFLEAFRLSD 599
BLAST of Serine/threonine-protein phosphatase with EF-hands vs. TrEMBL
Match: A0A267DFW7 (Serine/threonine-protein phosphatase with EF-hands OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig022204g1 PE=3 SV=1) HSP 1 Score: 708.753 bits (1828), Expect = 0.000e+0 Identity = 346/690 (50.14%), Postives = 467/690 (67.68%), Query Frame = 1 Query: 109 QMGCAQSNSPKHEYDNIYNSPKENIIENSKKTSHHVKKIYSTGDTG----------PISIKAAILIQNWYRRYRAKLEAKRRYTWMIYQSIEYSGEQDQLKLQSFFNDLLSLTNKGQECDSEVIEALSKTHVLKTAPTVSDEDRDLQYL---------------TKIEQIVVEPTYKGAKLTFPLSINQVTALIESFRKEQILHARYLLELLDHTRNLLKTKPNVSQASTSISKRVTICGDLHGQLDDLVTIFYKNKFPDTSNPYIINGDFVDRGSHSVEIAAILFSFFLLYPQSVFLNRGNHEDHVMNYRYGFVKEIQIKYKSNANKIVRFFADIFSWLPLMTIIDNSILVCHGGISAMLNLDVIEKLDRHKFLSVLQAPVEDIKNENKE---EEWMQILDLLWSDPRSKPGCSVNQYRGGGCYFGPDITNDILKKYNLSLLIRSHECKIDGYEWCHENKVVTLFSASNYYKQGSNKGAFLRIDNEHNKQFFQYTTHKKNQKHLTLIQSVNQIEESALRDLKGKILAFKNELAEEFIQKDVNNRGVIELQEWCTVMENVLKLPLPWRTLRPHLVKLSKEGKVEYSSIFEAQQVDNKFLM-----IAGTMTEELYKNKENLETIFRIMDKDNSGHISLSEFRDACKLLHRHTNRNVSEEAIEDLAKCLDINKDGQIDFNEFLEAFRIVDS 2079 +MGC S+S + + ++ ++ KK H +K + TG +SIK+A+LIQ WYRRY+A+LEA+RR TWMIYQSIEYS E QL L +FF+D++ L D + + + H+ +R + L T E I VE +Y+G L+FPLS + V LI+SFR+ LH+RYLL+LL R LLKTKPNV QASTSIS++VT+ GDLHG+LDDL+ IFYKN PD +NPY+ NGDFVDRG++SVE AA+LF+ L++P +VF+NRGNHEDH+MN RYGF+KE+Q KYK+ ANKIVR F D FSWLPL T ID+ ILV HGGIS ++++ ++KLDRH++LS L+ PV D NEN + +EW Q+LDLLWSDP+ + GC+ N +RGGGCYFGP+IT L+K+ SLL+RSHECK DG+E+CH V+TLFSASNYY+ GSNKGA+ + D E QY K + L + + ++ +EE AL+DL+ K++A K EL F + D + G I L +WC ME L+L LPWRTLRPHL +L+K+G++ Y + F+ + K +AG++TE +YKNKE LETIFRIMDKDNSG ISL EF+++C++L + T R ++E + D+A+ +D+N DG IDFNEFLEAFRI+D+ Sbjct: 33 KMGCGPSSSADDDSEQQQQPLQKQQKDDGKK--HGKQKRSKSPQTGGKDVTDASVEALSIKSALLIQKWYRRYKARLEARRRTTWMIYQSIEYSSEASQLHLYNFFSDMMQL------ADGKQPQQPQQQHLSPAGSGDPANNRFAERLRQKSLEEEDQELLELTSYEGIQVEKSYRGPHLSFPLSASHVQVLIDSFRQGTQLHSRYLLQLLHEARLLLKTKPNVYQASTSISRQVTVVGDLHGKLDDLLVIFYKNGLPDVTNPYVFNGDFVDRGANSVETAALLFACLLVWPSAVFINRGNHEDHLMNCRYGFIKEVQAKYKTPANKIVRLFGDTFSWLPLATNIDDKILVTHGGISDKVDMERVQKLDRHQYLSALKPPVSD--NENAKVDYKEWRQVLDLLWSDPKPQAGCAPNTFRGGGCYFGPNITEAFLRKHKFSLLVRSHECKPDGWEFCHGGAVLTLFSASNYYEDGSNKGAYAKFDAEGKPHIVQYMASKA--RKLPVGRRLSTVEEGALKDLRAKVIASKTELTAAFQRFDPDKTGSIRLADWCEAMEQTLRLGLPWRTLRPHLAQLAKDGRLLYMTSFDCVSIQTKLGASAGKEVAGSLTEAVYKNKEELETIFRIMDKDNSGQISLDEFQESCRVLTQATGRQMTEAEVGDMARSMDLNSDGYIDFNEFLEAFRIIDT 710
BLAST of Serine/threonine-protein phosphatase with EF-hands vs. TrEMBL
Match: A0A1I8F2Q4 (Serine/threonine-protein phosphatase with EF-hands OS=Macrostomum lignano OX=282301 PE=3 SV=1) HSP 1 Score: 693.345 bits (1788), Expect = 0.000e+0 Identity = 349/682 (51.17%), Postives = 466/682 (68.33%), Query Frame = 1 Query: 112 MGCAQSNSPKHEYDNIYNSPKENIIENSKKTSHHVKKIYSTGDTG----------PISIKAAILIQNWYRRYRAKLEAKRRYTWMIYQSIEYSGEQDQLKL-------QSFFNDLLSLTNKGQECDSEVIEALSKTHVLKTAPTVSDEDRDLQYLTKIEQIVVEPTYKGAKLTFPLSINQVTALIESFRKEQILHARYLLELLDHTRNLLKTKPNVSQASTSISKRVTICGDLHGQLDDLVTIFYKNKFPDTSNPYIINGDFVDRGSHSVEIAAILFSFFLL-YPQSVFLNRGNHEDHVMNYRYGFVKEIQIKYKSNANKIVRFFADIFSWLPLMTIIDNSILVCHGGISAMLNLDVIEKLDRHKFLSVLQAPVEDIKNENKE---EEWMQILDLLWSDPRSKPGCSVNQYRGGGCYFGPDITNDILKKYNLSLLIRSHECKIDGYEWCHENKVVTLFSASNYYKQGSNKGAFLRIDNEHNKQFFQYTTHKKNQKHLTLIQSVNQIEESALRDLKGKILAFKNELAEEFIQKDVNNRGVIELQEWCTVMENVLKLPLPWRTLRPHLVKLSKEGKVEYSSIFEAQQVDNKFLM-----IAGTMTEELYKNKENLETIFRIMDKDNSGHISLSEFRDACKLLHRHTNRNVSEEAIEDLAKCLDINKDGQIDFNEFLEAFRIVDS 2079 MGC S+S + + ++ ++ KK H +K + TG +SIK+A+LIQ WYRRY+A+LEA+RR TWMIYQSIEYS E QL L Q LS G ++ E L + ++ +ED++L LT E I VE +Y+G L+FPLS + V LI+SFR+ LH+RYLL+LL R LLKTKPNV QASTSIS++VT+ GDLHG+LDDL+ IFYKN PD +NPY+ NGDFVDRG++SVE AA+LF+ LL +P +VF+NRGNHEDH+MN RYGF+KE+Q KYK+ ANKIVR F D FSWLPL T ID+ ILV HGGIS ++++ ++KLDRH++LS L+ PV D NEN + +EW Q+LDLLWSDP+ + GC+ N +RGGGCYFGP+IT L+K+ SLL+RSHECK DG+E+CH V+TLFSASNYY+ GSNKGA+ + D E QY K + L + + ++ +EE AL+DL+ K++A K EL F + D + G I L +WC ME L+L LPWRTLRPHL +L+K+G++ Y + F+ + K +AG++TE +YKNKE LETIFRIMDKDNSG ISL EF+++C++L + T R ++E + D+A+ +D+N DG IDFNEFLEAFRI+D+ Sbjct: 1 MGCGPSSSADDDSEQQQQPLQKQQKDDGKK--HGKQKRSKSPQTGGKDVTDASVEALSIKSALLIQKWYRRYKARLEARRRTTWMIYQSIEYSSEASQLHLLQTESSPQQPQQQHLSPAGSGDPANNRFAERLRQK-------SLEEEDQELLELTSYEGIQVEKSYRGPHLSFPLSASHVQVLIDSFRQGTQLHSRYLLQLLHEARLLLKTKPNVYQASTSISRQVTVVGDLHGKLDDLLVIFYKNGLPDVTNPYVFNGDFVDRGANSVETAALLFACCLLVWPSAVFINRGNHEDHLMNCRYGFIKEVQAKYKTPANKIVRLFGDTFSWLPLATNIDDKILVTHGGISDKVDMERVQKLDRHQYLSALKPPVSD--NENAKVDYKEWRQVLDLLWSDPKPQAGCAPNTFRGGGCYFGPNITEAFLRKHKFSLLVRSHECKPDGWEFCHGGAVLTLFSASNYYEDGSNKGAYAKFDAEGKPHIVQYMASKA--RKLPVGRRLSTVEEGALKDLRAKVIASKTELTAAFQRFDPDKTGSIRLADWCEAMEQTLRLGLPWRTLRPHLAQLAKDGRLLYMTSFDCVSIQTKLGASAGKEVAGSLTEAVYKNKEELETIFRIMDKDNSGQISLDEFQESCRVLTQATGRQMTEAEVGDMARSMDLNSDGYIDFNEFLEAFRIIDT 669
BLAST of Serine/threonine-protein phosphatase with EF-hands vs. TrEMBL
Match: A0A1I8HDQ7 (Serine/threonine-protein phosphatase with EF-hands OS=Macrostomum lignano OX=282301 PE=3 SV=1) HSP 1 Score: 680.633 bits (1755), Expect = 0.000e+0 Identity = 321/636 (50.47%), Postives = 449/636 (70.60%), Query Frame = 1 Query: 250 ISIKAAILIQNWYRRYRAKLEAKRRYTWMIYQSIEYSGEQDQLKLQSFFNDLLSLTNKGQEC---DSEVIEALSKTHVLKTAPTVSDEDRDLQYLTKIEQIVVEPTYKGAKLTFPLSINQVTALIESFRKEQILHARYLLELLDHTRNLLKTKPNVSQASTSISK--------------------RVTICGDLHGQLDDLVTIFYKNKFPDTSNPYIINGDFVDRGSHSVEIAAILFSFFLLYPQSVFLNRGNHEDHVMNYRYGFVKEIQIKYKSNANKIVRFFADIFSWLPLMTIIDNSILVCHGGISAMLNLDVIEKLDRHKFLSVLQAPVEDIKNENKE-EEWMQILDLLWSDPRSKPGCSVNQYRGGGCYFGPDITNDILKKYNLSLLIRSHECKIDGYEWCHENKVVTLFSASNYYKQGSNKGAFLRIDNEHNKQFFQYTTHKKNQKHLTLIQSVNQIEESALRDLKGKILAFKNELAEEFIQKDVNNRGVIELQEWCTVMENVLKLPLPWRTLRPHLVKLSKEGKVEYSSIFEAQQVDNKFLM---IAGTMTEELYKNKENLETIFRIMDKDNSGHISLSEFRDACKLLHRHTNRNVSEEAIEDLAKCLDINKDGQIDFNEFLEAFRIVD 2076 +S+++A+LIQ WYRRY+A+LEA+R+ +WMIYQSIEYS E QL L +FFND+L L ++ E L + + + + + T +I VE YKG KL+FPLS V +I+SFR+ +LHARYLL+LL TR++LKT+ N+ S+SISK +VT+ GDLHG+L+DL+ + YKN PD +NPYI NGDFVDRG +SVEI AILF+ L++P +VFLNRGNHED VMN RYGF+KE+Q KY+ ANK++ F+++F+W+PL T+ID+ + V HGGIS ++LD + +LDRH+++SVL+ PV +E + EW Q+LDLLWSDP+++PGC N +RGGGCYFGP++T L KY LL+RSHECK DG+E+CHE+ V+T+FSASNYY++GSNKGA+++ D+E + Q+ ++++ L Q ++ +EESALRDL+GKILA K+EL + F++ D G I + +WC+ ME L+L LPWRTLRPHL +L+K+G++ Y S F+ + ++ +A ++TE +YKNKE LETIFRIMDKDNSG ISL EF+++C++L + T R ++E+ + D+AK LD+N DG IDFNEFLEAFRIVD Sbjct: 59 VSLQSAVLIQKWYRRYKARLEARRQTSWMIYQSIEYSSESSQLHLYNFFNDMLRLGGGSVGGASANAGFAERLRQRSIEEEDEELLEH-------TGYSEITVERNYKGPKLSFPLSATHVQLMIDSFRQGGLLHARYLLQLLHETRSVLKTRQNIQLVSSSISKQLDSVIKKLSLNANFHAPILKVTVVGDLHGKLEDLLIVLYKNGLPDVTNPYIFNGDFVDRGPNSVEILAILFACQLVWPSAVFLNRGNHEDQVMNLRYGFIKEVQYKYRQTANKVLNMFSEVFAWMPLATVIDDRVFVTHGGISDKVDLDRVRRLDRHRYVSVLRPPVAKSSDEKVDYMEWRQVLDLLWSDPKAQPGCKPNTFRGGGCYFGPNVTRAFLDKYGYKLLVRSHECKQDGWEFCHEDTVLTVFSASNYYEEGSNKGAYVKFDSECRPRLVQFVASRRDK--LPKGQRLSSVEESALRDLRGKILANKSELIDAFLRLDPEKTGAIRVSQWCSTMEEQLRLELPWRTLRPHLAQLNKDGRLLYMSTFQRAAIQHRLSGGKEMANSVTETVYKNKEELETIFRIMDKDNSGQISLEEFKESCRILCQATQRQMTEDEVADMAKSLDLNSDGYIDFNEFLEAFRIVD 685
BLAST of Serine/threonine-protein phosphatase with EF-hands vs. TrEMBL
Match: A0A2B4SS40 (Serine/threonine-protein phosphatase with EF-hands OS=Stylophora pistillata OX=50429 GN=Ppef1 PE=3 SV=1) HSP 1 Score: 678.707 bits (1750), Expect = 0.000e+0 Identity = 321/613 (52.37%), Postives = 441/613 (71.94%), Query Frame = 1 Query: 250 ISIKAAILIQNWYRRYRAKLEAKRRYTWMIYQSIEYSGEQDQLKLQSFFNDLLSLTNKGQECDSEVIEALSKTHVLKTAPTVSDEDRDLQYLTKIEQIVVEPTYKGAKLTFPLSINQVTALIESFRKEQILHARYLLELLDHTRNLLKTKPNVSQASTSISKRVTICGDLHGQLDDLVTIFYKNKFPDTSNPYIINGDFVDRGSHSVEIAAILFSFFLLYPQSVFLNRGNHEDHVMNYRYGFVKEIQIKYKSNANKIVRFFADIFSWLPLMTIIDNSILVCHGGISAMLNLDVIEKLDRHKFLSVLQAPVEDIKNENKEE--EWMQILDLLWSDPRSKPGCSVNQYRGGGCYFGPDITNDILKKYNLSLLIRSHECKIDGYEWCHENKVVTLFSASNYYKQGSNKGAFLRIDNEHNKQFFQYTTHKKNQKHLTLIQSVNQIEESALRDLKGKILAFKNELAEEFIQKDVNNRGVIELQEWCTVMENVLKLPLPWRTLRPHLVKLSKEGKVEYSSIFEAQQVDNKFLMIAGTMTEELYKNKENLETIFRIMDKDNSGHISLSEFRDACKLLHRHTNRNVSEEAIEDLAKCLDINKDGQIDFNEFLEAFRIVDSS 2082 I+I++AILIQ W+RRY+A++EA+RR TW I+QS+EY+GEQDQLKL +FFND+L+ G D+ ++ L K + T+S L+ LT +I VE TYKG + PL++ V +IE ++ ++LH +Y+L +L TR LK PN+ +AST ISK++TICGDLHG+LDDL IF+KN P NPYI NGD VDRG +SVEIA ILFSFFLLYP V++NRGNHEDH+MN RYGFVKE+ KYK +++K+++ F DIF WLPL T+++N IL+ HGGIS + +L I+K+DRHK++S+L+ P D + + + EW Q+LDLLWSDP+ PGC N +RGGGCYFGPDIT+ ILKK++L LL+RSHECK +GYE+ H KV+T+FSAS+YY+QGSN+GA+++I + N F QY K +KHLTL Q + +EESA+R+L+ ++ A K L F ++D N G + +W + +E+VLKL +PW LR L + +GKVEY S F+ ++ ++TE LY+++ NLETIFR+MDKDNSG +S+ EF + C LL+ HTN N+ ++IEDLAK +D++KDG IDFNEFLEAFR+VD S Sbjct: 22 IAIRSAILIQKWFRRYQARIEARRRCTWKIFQSVEYAGEQDQLKLFNFFNDMLNHVADG---DNNAVDILRKGSASSSTSTISKTSEKLEMLTDPSKITVEETYKGPHVALPLTLLTVRNIIELYKSHKLLHVKYVLLILRETREKLKVLPNIYRASTRISKQITICGDLHGKLDDLFVIFHKNGLPSAENPYIFNGDLVDRGPYSVEIAIILFSFFLLYPTGVYINRGNHEDHIMNLRYGFVKEVMDKYKEHSSKVMQLFGDIFGWLPLATVVNNKILITHGGISNITDLSFIDKIDRHKYVSILKPPGMDKAHPDTFDLLEWRQVLDLLWSDPKPFPGCKPNTFRGGGCYFGPDITDRILKKHDLELLVRSHECKFEGYEYMHGGKVITIFSASDYYEQGSNRGAYMKIGPDMNPYFVQYQA-SKAKKHLTLKQRIGIVEESAIRELRERLYANKIALMAAFEERDKGNTGYLTATQWASAVESVLKLDVPWNMLRHQLAHVLPDGKVEYRSCFDQYIIETGLHKNGPSITETLYRHRSNLETIFRLMDKDNSGFVSMEEFEECCHLLNEHTNSNIPVDSIEDLAKSIDMDKDGHIDFNEFLEAFRLVDHS 630
BLAST of Serine/threonine-protein phosphatase with EF-hands vs. TrEMBL
Match: A0A1I8IY93 (Serine/threonine-protein phosphatase OS=Macrostomum lignano OX=282301 PE=3 SV=1) HSP 1 Score: 677.937 bits (1748), Expect = 0.000e+0 Identity = 329/629 (52.31%), Postives = 446/629 (70.91%), Query Frame = 1 Query: 232 TGDTGPISIKAAILIQNWYRRYRAKLEAKRRYTWMIYQSIEYSGEQDQLKLQSFFNDLLSLT------NKGQECDSEVIEALSKTHVLKTAP----TVSDEDRDLQYLTKIEQIVVEPTYKGAKLTFPLSINQVTALIESFRKEQILHARYLLELLDHTRNLLKTKPNVSQASTSISKRVTICGDLHGQLDDLVTIFYKNKFPDTSNPYIINGDFVDRGSHSVEIAAILFSFFLLYPQSVFLNRGNHEDHVMNYRYGFVKEIQIKYKSNANKIVRFFADIFSWLPLMTIIDNSILVCHGGISAMLNLDVIEKLDRHKFLSVLQAPVEDIKNENKEEEWMQILDLLWSDPRSKPGCSVNQYRGGGCYFGPDITNDILKKYNLSLLIRSHECKIDGYEWCHENKVVTLFSASNYYKQGSNKGAFLRIDNEHNKQFFQYTTHKKNQKHLTLIQSVNQIEESALRDLKGKILAFKNELAEEFIQKDVNNRGVIELQEWCTVMENVLKLPLPWRTLRPHLVKLSKEGKVEYSSIFEAQQVDNKFLM----IAGTMTEELYKNKENLETIFRIMDKDNSGHISLSEFRDACKLLHRHTNRNVSEEAIEDLAKCLDINKDGQIDFNEFLEAFRIVD 2076 G ISI++A+LIQ WYRRY+A+LEA+RR TWMIYQSIEYS E QL L +FFND+LSLT + +E ++ H T + +EDR+L LT + VE +Y+G LTFPLS + V +I+SFR+ LH RYLL+LL TR L+ KPNV ASTSISK+VT+ GDLHG+LDDL+ +FYKN PD +NPY+ NGDFVDRG++SVE+AA+LF+ L++P +V +NRGNHEDHVMN RYGF+KE+Q KY+ +A+KIV+ FA++F+W+PL T+ID+ ILV HGGIS L+L+++ +LDRH++LS L+ P D + + EW Q+LDLLWSDP+ + GC N +RGGGCYFGPD+T L+K L+LL+RSHECK DGYE+CH+ V+T+FSASNYY++GSN+GA+++ D+ QY + + L + + ++ +EE AL+ L+ ++LA K EL F + D G I L +WC M+ L+L LPWRTLRPHL +L+K G++ Y + FE +D L +A ++TE +YKNKE LETIFRIMDKD+SG ISL EFRD+C++L T R +++ +E +AK +D+N DG IDFNEFLEAFRIVD Sbjct: 129 AASAGEISIRSAVLIQKWYRRYKARLEARRRTTWMIYQSIEYSSESSQLHLYNFFNDMLSLTGVGGGGHPSGAAAAEPLKTCVVGHRRFTERLRQLSQEEEDRELLDLTSFADLSVEKSYRGPHLTFPLSASHVQLMIDSFRQGGQLHPRYLLQLLHETRLALRAKPNVHSASTSISKQVTVIGDLHGKLDDLLIVFYKNGLPDITNPYVFNGDFVDRGANSVEVAALLFACQLVWPTAVCVNRGNHEDHVMNCRYGFIKEVQTKYRHSASKIVKLFAEVFAWMPLATLIDDRILVAHGGISDKLDLELLRRLDRHRYLSALRPPGNDGEKVDY-LEWRQVLDLLWSDPKPQAGCRPNTFRGGGCYFGPDVTESFLRKNKLTLLVRSHECKQDGYEFCHDGAVLTVFSASNYYEEGSNRGAYVKFDSSGKPHIVQYMASR--SRRLPVGRRLSTVEEGALKGLRARVLASKTELLAAFQRLDPGRTGAIRLADWCQAMDETLRLDLPWRTLRPHLAELNKSGRLLYMTCFERVALDAGRLAGTKEVAASLTEAVYKNKEELETIFRIMDKDSSGQISLEEFRDSCRVLSEATGRQMADAEVEAMAKAMDLNNDGYIDFNEFLEAFRIVD 754
BLAST of Serine/threonine-protein phosphatase with EF-hands vs. Ensembl Cavefish
Match: ppef1 (serine/threonine-protein phosphatase with EF-hands 1 [Source:NCBI gene;Acc:103021363]) HSP 1 Score: 333.183 bits (853), Expect = 3.350e-103 Identity = 163/319 (51.10%), Postives = 219/319 (68.65%), Query Frame = 1 Query: 223 IYSTGDTGPISIKAAILIQNWYRRYRAKLEAKRRYTWMIYQSIEYSGEQDQLKLQSFFNDLLSLTNKGQECDSEVIEALSKTHVLKTA-PTVSDEDRDLQYLTKIEQIVVEPTYKGAKLTFPLSINQVTALIESFRKEQILHARYLLELLDHTRNLLKTKPNVSQASTSISKRVTICGDLHGQLDDLVTIFYKNKFPDTSNPYIINGDFVDRGSHSVEIAAILFSFFLLYPQSVFLNRGNHEDHVMNYRYGFVKEIQIKYKSNANKIVRFFADIFSWLPLMTIIDNSILVCHGGISAMLNLDVIEKLDRHKFLSVLQAP 1176 I + G +++KAAILIQ WYRRY A+LE +RRYTW I+QSIEY+GEQDQL+L SFF+ +L + ++I +H+L +A V DE R +Y EQIVV +Y G +L+FPLS+ L+ +F+++Q LHA+Y+L+LL T+ LK PNV S+S +K +TICGDLHG+LDDL+ IFYKN P NPYI NGDFVDRG S+EI ILF+F LLYP + LNRGNHEDH+MN RYGF KE+ KYK++ +I++ D+FS LP+ TIIDN +L+ HGGIS +L+ + ++R K S L+ P Sbjct: 9 IENQGRPSEVAMKAAILIQRWYRRYVARLEMRRRYTWNIFQSIEYAGEQDQLQLSSFFSFMLDNFTQLNGNGPDLI-----SHLLDSAVDPVVDEVRQSKY----EQIVVPESYSGPRLSFPLSVTDTNVLLSAFKEQQTLHAKYVLQLLHETQKFLKQMPNVIYLSSSYAKEITICGDLHGRLDDLLLIFYKNGLPSAENPYIFNGDFVDRGKKSIEIIIILFAFLLLYPDHMHLNRGNHEDHIMNLRYGFTKEVMQKYKTHGREILQLLQDVFSLLPIATIIDNKVLIVHGGISDKTDLEFLASVERQKVKSALRLP 318 HSP 2 Score: 323.168 bits (827), Expect = 1.883e-99 Identity = 151/291 (51.89%), Postives = 203/291 (69.76%), Query Frame = 1 Query: 1201 KEEEWMQILDLLWSDPRSKPGCSVNQYRGGGCYFGPDITNDILKKYNLSLLIRSHECKIDGYEWCHENKVVTLFSASNYYKQGSNKGAFLRIDNEHNKQFFQYTTHKKNQKHLTLIQSVNQIEESALRDLKGKILAFKNELAEEFIQKDVNNRGVIELQEWCTVMENVLKLPLPWRTLRPHLVKLSKEGKVEYSSIFEAQQVDNKFLMIAGTMTEELYKNKENLETIFRIMDKDNSGHISLSEFRDACKLLHRHTNRNVSEEAIEDLAKCLDINKDGQIDFNEFLEAFRIV 2073 +E EW QI+D+LWSDP+ + GCS N +RGGGCYFGPD+T ++LKK+ L LLIRSHECK +GYE CH +V+T+FSASNYY++GSN+GA++++ E +FFQY + +K LTL Q V+ E SAL+ L+ K+ ++EL F Q D+NN G I + EW V++ VL+L LPWRTLRP LV+L+ +G VEY S FE + E LY+ + +LE IF I+DKD+SG IS+ EFR KL H +V ++AI D+A+ +D NKDG IDFNEFLEAFR+V Sbjct: 417 EELEWRQIVDVLWSDPKIQNGCSPNSFRGGGCYFGPDVTQNLLKKHGLCLLIRSHECKQEGYELCHNGQVITIFSASNYYEEGSNRGAYIKLGPELIPRFFQYQVSRSTRK-LTLQQRVSVAESSALKALQEKLFTHRSELMAFFQQYDINNTGRISINEWAQVLDTVLRLDLPWRTLRPRLVRLASDGNVEYESCFENISAGQPLPQVTPNFAETLYRYRTDLEIIFNIIDKDHSGQISIEEFRQTWKLFSAHLGVDVDDQAIVDMARNIDFNKDGSIDFNEFLEAFRVV 706
BLAST of Serine/threonine-protein phosphatase with EF-hands vs. Ensembl Cavefish
Match: ppef1 (serine/threonine-protein phosphatase with EF-hands 1 [Source:NCBI gene;Acc:103021363]) HSP 1 Score: 330.872 bits (847), Expect = 2.747e-102 Identity = 161/310 (51.94%), Postives = 216/310 (69.68%), Query Frame = 1 Query: 250 ISIKAAILIQNWYRRYRAKLEAKRRYTWMIYQSIEYSGEQDQLKLQSFFNDLLSLTNKGQECDSEVIEALSKTHVLKTA-PTVSDEDRDLQYLTKIEQIVVEPTYKGAKLTFPLSINQVTALIESFRKEQILHARYLLELLDHTRNLLKTKPNVSQASTSISKRVTICGDLHGQLDDLVTIFYKNKFPDTSNPYIINGDFVDRGSHSVEIAAILFSFFLLYPQSVFLNRGNHEDHVMNYRYGFVKEIQIKYKSNANKIVRFFADIFSWLPLMTIIDNSILVCHGGISAMLNLDVIEKLDRHKFLSVLQAP 1176 +++KAAILIQ WYRRY A+LE +RRYTW I+QSIEY+GEQDQL+L SFF+ +L + ++I +H+L +A V DE R +Y EQIVV +Y G +L+FPLS+ L+ +F+++Q LHA+Y+L+LL T+ LK PNV S+S +K +TICGDLHG+LDDL+ IFYKN P NPYI NGDFVDRG S+EI ILF+F LLYP + LNRGNHEDH+MN RYGF KE+ KYK++ +I++ D+FS LP+ TIIDN +L+ HGGIS +L+ + ++R K S L+ P Sbjct: 29 LTMKAAILIQRWYRRYVARLEMRRRYTWNIFQSIEYAGEQDQLQLSSFFSFMLDNFTQLNGNGPDLI-----SHLLDSAVDPVVDEVRQSKY----EQIVVPESYSGPRLSFPLSVTDTNVLLSAFKEQQTLHAKYVLQLLHETQKFLKQMPNVIYLSSSYAKEITICGDLHGRLDDLLLIFYKNGLPSAENPYIFNGDFVDRGKKSIEIIIILFAFLLLYPDHMHLNRGNHEDHIMNLRYGFTKEVMQKYKTHGREILQLLQDVFSLLPIATIIDNKVLIVHGGISDKTDLEFLASVERQKVKSALRLP 329 HSP 2 Score: 323.168 bits (827), Expect = 2.248e-99 Identity = 151/291 (51.89%), Postives = 203/291 (69.76%), Query Frame = 1 Query: 1201 KEEEWMQILDLLWSDPRSKPGCSVNQYRGGGCYFGPDITNDILKKYNLSLLIRSHECKIDGYEWCHENKVVTLFSASNYYKQGSNKGAFLRIDNEHNKQFFQYTTHKKNQKHLTLIQSVNQIEESALRDLKGKILAFKNELAEEFIQKDVNNRGVIELQEWCTVMENVLKLPLPWRTLRPHLVKLSKEGKVEYSSIFEAQQVDNKFLMIAGTMTEELYKNKENLETIFRIMDKDNSGHISLSEFRDACKLLHRHTNRNVSEEAIEDLAKCLDINKDGQIDFNEFLEAFRIV 2073 +E EW QI+D+LWSDP+ + GCS N +RGGGCYFGPD+T ++LKK+ L LLIRSHECK +GYE CH +V+T+FSASNYY++GSN+GA++++ E +FFQY + +K LTL Q V+ E SAL+ L+ K+ ++EL F Q D+NN G I + EW V++ VL+L LPWRTLRP LV+L+ +G VEY S FE + E LY+ + +LE IF I+DKD+SG IS+ EFR KL H +V ++AI D+A+ +D NKDG IDFNEFLEAFR+V Sbjct: 428 EELEWRQIVDVLWSDPKIQNGCSPNSFRGGGCYFGPDVTQNLLKKHGLCLLIRSHECKQEGYELCHNGQVITIFSASNYYEEGSNRGAYIKLGPELIPRFFQYQVSRSTRK-LTLQQRVSVAESSALKALQEKLFTHRSELMAFFQQYDINNTGRISINEWAQVLDTVLRLDLPWRTLRPRLVRLASDGNVEYESCFENISAGQPLPQVTPNFAETLYRYRTDLEIIFNIIDKDHSGQISIEEFRQTWKLFSAHLGVDVDDQAIVDMARNIDFNKDGSIDFNEFLEAFRVV 717
BLAST of Serine/threonine-protein phosphatase with EF-hands vs. Ensembl Cavefish
Match: ENSAMXT00000016118.2 (pep primary_assembly:Astyanax_mexicanus-2.0:14:38271079:38284894:-1 gene:ENSAMXG00000015666.2 transcript:ENSAMXT00000016118.2 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 313.923 bits (803), Expect = 5.991e-96 Identity = 150/307 (48.86%), Postives = 208/307 (67.75%), Query Frame = 1 Query: 256 IKAAILIQNWYRRYRAKLEAKRRYTWMIYQSIEYSGEQDQLKLQSFFNDLLSLTNKGQECDSEVIEALSKTHVLKTAPTVSDEDRDLQYLTKIEQIVVEPTYKGAKLTFPLSINQVTALIESFRKEQILHARYLLELLDHTRNLLKTKPNVSQASTSISKRVTICGDLHGQLDDLVTIFYKNKFPDTSNPYIINGDFVDRGSHSVEIAAILFSFFLLYPQSVFLNRGNHEDHVMNYRYGFVKEIQIKYKSNANKIVRFFADIFSWLPLMTIIDNSILVCHGGISAMLNLDVIEKLDRHKFLSVLQAP 1176 ++AA+LIQ WYR+Y A+LE +RR TW I+QSIEYSGEQDQ+KL +FF L+ + + +H+ + + D + + + K I V Y G LTFPL++N +T L+E+F+ +Q LHARY+L+LL T LL+ PN+++ ST SK +TICGDLHGQL+DL+ +FYKN P PY+ NGDFVDRG S+EI ILF+F L+YP V LNRGNHEDH++N RYGF KE+ KY+ + KI++ IFSWLPL T+ID +L+ HGGIS +L +I KL+R++++S L+ P Sbjct: 1 MRAALLIQRWYRQYVARLEMRRRCTWNIFQSIEYSGEQDQIKLYNFFGFLMDHFTPASSERNLI------SHIFRESEVFQDAEWEPYFCYK--SIDVPDMYTGPHLTFPLTVNIITELVEAFKHKQHLHARYVLQLLGETWRLLRILPNINEVSTFHSKEITICGDLHGQLEDLLLVFYKNGLPSVETPYVFNGDFVDRGKDSIEILLILFAFQLVYPNDVHLNRGNHEDHIVNLRYGFTKEVLGKYRVHGKKILKLLQKIFSWLPLATVIDQKVLILHGGISDTTDLKLIAKLERNRYVSALRPP 299 HSP 2 Score: 299.286 bits (765), Expect = 1.663e-90 Identity = 148/298 (49.66%), Postives = 199/298 (66.78%), Query Frame = 1 Query: 1195 ENKEEEWMQILDLLWSDPRSKPGCSVNQYRGGGCYFGPDITNDILKKYNLSLLIRSHECKIDGYEWCHENKVVTLFSASNYYKQGSNKGAFLRIDNEHNKQFFQYTTHKKNQKHLTLIQSVNQIEESALRDLKGKILAFKNELAEEFIQKDVNNRGVIELQEWCTVMENVLKLPLPWRTLRPHLVKLS-KEGKVEYSSIF-EAQQVDNKFLMIAGTMTEELYKNKENLETIFRIMDKDNSGHISLSEFRDACKLLHRHTNRNVSEEAIEDLAKCLDINKDGQIDFNEFLEAFRIVDSS 2082 E EEW QI+D+LWSDP S+ GC N+ RGGGCY+GPDIT D+L ++NL LLIRSHECK DGYE+CH +V+T+FSASNYY+ GSN+GA++R+ + N QY ++ + LTL QSV + E SALR L+ ++ A K++L + + D + GVI ++ W E VL+L LPWR LR LV S ++G + Y+ F E +D + + E +Y++ NLETIFRI+D D+SG IS EFR KLL H +S++AI DLA +D NKDG ID NEF+EAFR+VD S Sbjct: 398 ETDAEEWKQIVDMLWSDPMSQDGCIPNEVRGGGCYWGPDITEDVLNRHNLRLLIRSHECKQDGYEFCHNRRVLTIFSASNYYEVGSNRGAYIRLGPDLNPHVVQYQA-SRSTRELTLRQSVGRTERSALRALREQVFAHKSDLTSAYEEFDPEHTGVISMKHWAVATETVLQLGLPWRVLREQLVGDSTQDGIINYNDWFRELALMDPNTELAHTGLLETMYRHHSNLETIFRIIDTDHSGLISFEEFRQTWKLLSSHLKMEISDKAISDLALSIDFNKDGSIDINEFMEAFRLVDCS 694
BLAST of Serine/threonine-protein phosphatase with EF-hands vs. Ensembl Cavefish
Match: PPEF2 (protein phosphatase with EF-hand domain 2 [Source:HGNC Symbol;Acc:HGNC:9244]) HSP 1 Score: 295.049 bits (754), Expect = 2.793e-88 Identity = 146/308 (47.40%), Postives = 203/308 (65.91%), Query Frame = 1 Query: 253 SIKAAILIQNWYRRYRAKLEAKRRYTWMIYQSIEYSGEQDQLKLQSFFNDLLSLTNKGQECDSEVIEALSKTHVLKTAPTVSDEDRDLQYLTKIEQIVVEPTYKGAKLTFPLSINQVTALIESFRKEQILHARYLLELLDHTRNLLKTKPNVSQASTSISKRVTICGDLHGQLDDLVTIFYKNKFPDTSNPYIINGDFVDRGSHSVEIAAILFSFFLLYPQSVFLNRGNHEDHVMNYRYGFVKEIQIKYKSNANKIVRFFADIFSWLPLMTIIDNSILVCHGGISAMLNLDVIEKLDRHKFLSVLQAP 1176 +I+AA+LIQ WYR+Y A++E +RRYTW I+QSIEY+G+QDQ+KL +F L+ + + + V + D + + I V Y G +LTFPL+ +Q L+E+FR +Q LH+RY+L+LL T LL+ PN+++ ST SK +TICGDLHGQL+DL+ IFYKN P Y+ NGDFVDRG S+EI ILF+F L+YP V LNRGNHEDH++N RYGF KE+ KYK + +I++ IFSWLPL T+ID +L+ HGGIS +L ++ ++DRHK++S L+ P Sbjct: 32 AIRAAVLIQRWYRQYVARMELRRRYTWNIFQSIEYAGQQDQIKLYNFLGYLVDNFTPSSNERNLISHIFRENEVCR--------DIEWERFFDYRHIEVPDIYSGPRLTFPLNADQAADLVEAFRSKQQLHSRYVLQLLGETWKLLRVLPNINRISTCHSKEITICGDLHGQLEDLLLIFYKNGMPSMEKAYVFNGDFVDRGKDSIEILLILFAFLLVYPGEVHLNRGNHEDHIINLRYGFTKEVLGKYKMHGKRILKLLQKIFSWLPLATVIDQKVLIVHGGISDTTDLALVARVDRHKYVSSLRPP 331 HSP 2 Score: 286.189 bits (731), Expect = 5.487e-85 Identity = 138/298 (46.31%), Postives = 197/298 (66.11%), Query Frame = 1 Query: 1195 ENKEEEWMQILDLLWSDPRSKPGCSVNQYRGGGCYFGPDITNDILKKYNLSLLIRSHECKIDGYEWCHENKVVTLFSASNYYKQGSNKGAFLRIDNEHNKQFFQYTTHKKNQKHLTLIQSVNQIEESALRDLKGKILAFKNELAEEFIQKDVNNRGVIELQEWCTVMENVLKLPLPWRTLRPHLVKLSKEGKVEYSSIFEAQQVDNK-FLMIAGTMTEELYKNKENLETIFRIMDKDNSGHISLSEFRDACKLLHRHTNRNVSEEAIEDLAKCLDINKDGQIDFNEFLEAFRIVDSSL 2085 EN + EW QILDLLWSDP GC N+ RGGGCY+GP++T + L K+++ L+IRSHECK DGYE+CH KV+T+FSASNYY+ GSN+GAF+R+ + F QY + + +++ QS+ + E SAL+ L+ ++ A K++L F Q D N G+I L +W + M VL L LPWR LR L+ + + ++Y + F + K + I T+ + LYK++ LETIFRI+D DNSG IS +FR KLL+ + +SEE+I DL +D NKDG ID +EF+E+FR+VD ++ Sbjct: 436 ENVQNEWKQILDLLWSDPMIPDGCVPNEVRGGGCYWGPNVTEEFLNKHSMQLIIRSHECKQDGYEFCHNRKVLTIFSASNYYEVGSNRGAFVRLGPDLVPYFIQYQANSMT-REMSVRQSLRRTEHSALKVLREQLFAHKSDLMSAFQQHDKENTGLISLSDWGSAMSQVLHLDLPWRMLRSQLITTTTDDMLDYHNWFRNLAIKEKSYEHIEQTLLDTLYKHRSTLETIFRIVDTDNSGFISFEDFRQTWKLLNAYLKMEISEESINDLVVSIDTNKDGNIDIDEFMESFRLVDKNM 732
BLAST of Serine/threonine-protein phosphatase with EF-hands vs. Ensembl Cavefish
Match: ppp5c (protein phosphatase 5 catalytic subunit [Source:NCBI gene;Acc:103034548]) HSP 1 Score: 234.958 bits (598), Expect = 1.004e-68 Identity = 125/332 (37.65%), Postives = 194/332 (58.43%), Query Frame = 1 Query: 532 IEQIVVEPTYKGAKLT-FPLSINQVTALIESFRKEQILHARYLLELLDHTRNLLKTKPNVSQASTSISKRVTICGDLHGQLDDLVTIFYKNKFPDTSNPYIINGDFVDRGSHSVEIAAILFSFFLLYPQSVFLNRGNHEDHVMNYRYGFVKEIQIKYKSNANKIVRFFADIFSWLPLMTIIDNSILVCHGGISA--MLNLDVIEKLDRHKFLSVLQAPVEDIKNENKEEEWMQILDLLWSDPRSKPGCSVNQYRGGGCYFGPDITNDILKKYNLSLLIRSHECKIDGYEWCHENKVVTLFSASNYYKQGSNKGAFLRIDNEHNK-QFFQYTT 1515 IE + +E Y G KL +++ + +++ F+ ++ LH + ++L + +L P++ + + ++++TICGD HGQ DL+ IF N P +NPY+ NGDFVDRGS S+E+ LF F LLYP L RGNHE MN YGF E++ KY + ++ + F+++F WLPL I++ +LV HGG+ + + LD + K+DR++ Q P + + DLLWSDP+ + G S+++ RG C FGPD+T L++ L ++RSHE K +GYE H K +T+FSA NY Q NKGA++ + K +F Q+T Sbjct: 160 IENMTIEDEYAGPKLEDGKVTLKFMKEMMDWFKDQKKLHRKCAYQMLVQVKEVLSKLPSLVEITLKETEKITICGDTHGQYYDLLNIFELNGLPSPTNPYLFNGDFVDRGSFSMEVILTLFGFKLLYPDHFHLLRGNHETDNMNQMYGFEGEVKAKYTA---QMFQLFSEVFQWLPLAQCINSKVLVMHGGLFSEDGVTLDDLRKIDRNR-----QPP-----------DSGPMCDLLWSDPQPQNGRSISK-RGVSCQFGPDVTQRFLEQNKLQYIVRSHEVKAEGYEVTHSGKCITVFSAPNYCDQMGNKGAYIHLRGSDLKPEFHQFTA 471
BLAST of Serine/threonine-protein phosphatase with EF-hands vs. Ensembl Sea Lamprey
Match: ppp5c (protein phosphatase 5, catalytic subunit [Source:ZFIN;Acc:ZDB-GENE-050327-75]) HSP 1 Score: 239.195 bits (609), Expect = 2.752e-71 Identity = 146/408 (35.78%), Postives = 226/408 (55.39%), Query Frame = 1 Query: 274 IQNWYRRYRAKLE-AKRRYTWMIYQSIEYSGEQDQ-LKLQSFFNDLLSLTNKGQECDSEVIEALSKTHVLKTAPTVSDEDRDLQYLTKIEQIVVEPTYKGAKL-TFPLSINQVTALIESFRKEQILHARYLLELLDHTRNLLKTKPNVSQASTSISK--RVTICGDLHGQLDDLVTIFYKNKFPDTSNPYIINGDFVDRGSHSVEIAAILFSFFLLYPQSVFLNRGNHEDHVMNYRYGFVKEIQIKYKSNANKIVRFFADIFSWLPLMTIIDNSILVCHGGISA--MLNLDVIEKLDRHKFLSVLQAPVEDIKNENKEEEWMQILDLLWSDPRSKPGCSVNQYRGGGCYFGPDITNDILKKYNLSLLIRSHECKIDGYEWCHENKVVTLFSASNYYKQGSNKGAFLRI 1476 I+ +YRR AK+ K + Y+++ D+ KL K QEC S+++ K + A D + + ++ + +E Y G K+ ++I + LIE F+ ++ LH +Y ++L + L+ P++ + + + +T+CGD+HGQ DL+ IF N P +NPY+ NGDFVDRGS SVE+ +LF F LLYP L RGNHE MN YGF E++ KY + ++ FF+++F WLPL I++ +L+ HGG+ + + LD I K+DR++ Q P + + DLLWSDP+ +PG SV++ RG C FGPD++ +++ NL L+IRSHE K DGYE H+ + VT+FSA NY Q NKG+++ + Sbjct: 56 IKGYYRRATAKMALGKFKEALKDYETVVKVKPNDKDAKL------------KYQEC-SKIV----KRKAFERAIASDDSKKSVADALDLDSMAIEDDYTGPKVDNGQVTITFMKELIEWFKDQKKLHRKYAYQILLQVKQSLQKLPSLVEVTIKDEQGDMITVCGDIHGQYFDLLHIFELNGLPSETNPYVFNGDFVDRGSWSVEVILVLFGFKLLYPDHFHLMRGNHETDNMNQMYGFEGEVKAKYTA---QMFDFFSEVFQWLPLAMCINSRVLIMHGGLFSEDGVTLDDIRKIDRNR-----QPP-----------DSGPMCDLLWSDPQPQPGRSVSK-RGVSCQFGPDVSRAFMEQNNLELIIRSHE-KPDGYEVAHDGRCVTVFSAPNYCDQMGNKGSYIHL 425
BLAST of Serine/threonine-protein phosphatase with EF-hands vs. Ensembl Sea Lamprey
Match: ppp1cab (protein phosphatase 1, catalytic subunit, alpha isozyme b [Source:ZFIN;Acc:ZDB-GENE-030131-5512]) HSP 1 Score: 154.836 bits (390), Expect = 2.673e-42 Identity = 93/248 (37.50%), Postives = 139/248 (56.05%), Query Frame = 1 Query: 739 VTICGDLHGQLDDLVTIFYKNKFPDTSNPYIINGDFVDRGSHSVEIAAILFSFFLLYPQSVFLNRGNHEDHVMNYRYGFVKEIQIKYKSNANKIVRFFADIFSWLPLMTIIDNSILVCHGGISAMLNLDVIEKLDRHKFLSVLQAPVEDIKNENKEEEWMQILDLLWSDP-RSKPGCSVNQYRGGGCYFGPDITNDILKKYNLSLLIRSHECKIDGYEWCHENKVVTLFSASNYYKQGSNKGAFLRID 1479 + ICGD+HGQ DL+ +F FP SN Y+ GD+VDRG S+E +L ++ + YP++ FL RGNHE + N YGF E + +Y K+ + F D F+ LP+ I+D I CHGG+S +L +E++ R + P D+ ++ + DLLWSDP + G N RG FG ++ L K++L L+ R+H+ DGYE+ + ++VTLFSA NY + N GA + +D Sbjct: 41 LKICGDIHGQYYDLLRLFEYGGFPPESN-YLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHEASI-NRIYGFYDECKRRYNI---KLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSP--DLQSMEQIRR------IMRPT-DVPDQG------LLCDLLWSDPDKDTMGWGEND-RGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVD 267
BLAST of Serine/threonine-protein phosphatase with EF-hands vs. Ensembl Sea Lamprey
Match: ENSPMAT00000010086.1 (pep scaffold:Pmarinus_7.0:GL479411:90249:92178:-1 gene:ENSPMAG00000009123.1 transcript:ENSPMAT00000010086.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 148.673 bits (374), Expect = 1.841e-40 Identity = 88/244 (36.07%), Postives = 136/244 (55.74%), Query Frame = 1 Query: 751 GDLHGQLDDLVTIFYKNKFPDTSNPYIINGDFVDRGSHSVEIAAILFSFFLLYPQSVFLNRGNHEDHVMNYRYGFVKEIQIKYKSNANKIVRFFADIFSWLPLMTIIDNSILVCHGGISAMLNLDVIEKLDRHKFLSVLQAPVEDIKNENKEEEWMQILDLLWSDP-RSKPGCSVNQYRGGGCYFGPDITNDILKKYNLSLLIRSHECKIDGYEWCHENKVVTLFSASNYYKQGSNKGAFLRID 1479 GD+HGQ DL+ +F FP +N Y+ GD+VDRG S+E +L ++ + YP++ FL RGNHE +N YGF E + ++ K+ + F D F+ LP+ I+D I CHGG+S +L +E++ R + P D+ + + + DLLWSDP + G N RG FG D+ + L +++L L+ R+H+ DGYE+ + ++VTLFSA NY + N G + +D Sbjct: 1 GDIHGQYTDLLRLFEYGGFPPEAN-YLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRFNI---KLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSP--DLQSMEQIRR------IMRPT-DVPDTG---DAGLLCDLLWSDPDKDVQGWGEND-RGVSFTFGGDVVSKFLNRHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGGMMSVD 227
BLAST of Serine/threonine-protein phosphatase with EF-hands vs. Ensembl Sea Lamprey
Match: ppp3cb (protein phosphatase 3, catalytic subunit, beta isozyme [Source:ZFIN;Acc:ZDB-GENE-050417-406]) HSP 1 Score: 134.035 bits (336), Expect = 1.553e-33 Identity = 89/267 (33.33%), Postives = 130/267 (48.69%), Query Frame = 1 Query: 727 ISKRVTICGDLHGQLDDLVTIFYKNKFPDTSNPYIINGDFVDRGSHSVEIAAILFSFFLLYPQSVFLNRGNHEDHVMNYRYGFVKEIQIKYKSNANKIVRFFADIFSWLPLMTIIDNSILVCHGGISAML-NLDVIEKLDRHKFLSVLQAPVEDIKNENKEEEWMQILDLLWSDPRSKPG--------CSVNQYRGGGCYFGPDITNDILKKYNLSLLIRSHECKIDGYEWCHENK------VVTLFSASNYYKQGSNKGAFLRIDN 1482 I VT+CGD+HGQ DL+ +F P + Y+ GD+VDRG S+E L++ +LYP ++FL RGNHE + + F +E +IKY D F LPL +++ L HGG+S + NL+ I KLDR K + + + DLLWSDP G C N RG ++ D L+ NL +IR+HE + GY +++ ++T+FSA NY +NK A L+ +N Sbjct: 64 IEAPVTVCGDIHGQFFDLMKLFEVGGSPANTR-YLFLGDYVDRGYFSIECVLYLWALKILYPTTLFLLRGNHECRHLTEYFTFKQECKIKYTETVYDAC---MDAFDCLPLAALMNQQFLCVHGGLSPEVHNLEDIRKLDRFK----------------EPPAFGPMCDLLWSDPSEDFGNEKTQEYFCH-NTVRGCSYFYSYPAVCDFLQNNNLLSVIRAHEAQDAGYRMYRKSQTTGFPSLITIFSAPNYLDVYNNKAAVLKYEN 309
BLAST of Serine/threonine-protein phosphatase with EF-hands vs. Ensembl Sea Lamprey
Match: ppp1cb (protein phosphatase 1, catalytic subunit, beta isozyme [Source:ZFIN;Acc:ZDB-GENE-030616-609]) HSP 1 Score: 114.39 bits (285), Expect = 4.779e-29 Identity = 70/195 (35.90%), Postives = 102/195 (52.31%), Query Frame = 1 Query: 739 VTICGDLHGQLDDLVTIFYKNKFPDTSNPYIINGDFVDRGSHSVEIAAILFSFFLLYPQSVFLNRGNHEDHVMNYRYGFVKEIQIKYKSNANKIVRFFADIFSWLPLMTIIDNSILVCHGGISAMLNLDVIEKLDRHKFLSVLQAPVEDIKNENKEEEWMQILDLLWSDP-RSKPGCSVNQYRGGGCYFGPDITN 1320 + ICGD+HGQ DL+ +F FP SN Y+ GD+VDRG S+E +L ++ + YP++ FL RGNHE +N YGF E + ++ K+ + F D F+ LP+ I+D I CHGG+S +L +E++ R I + + DLLWSDP + G N RG FG D+ + Sbjct: 45 LKICGDIHGQYTDLLRLFEYGGFPPESN-YLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRFNI---KLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSP--DLQSMEQIRR-------------IMRPTDVPDTGLLCDLLWSDPDKDVQGWGEND-RGVSFTFGADVVS 219
BLAST of Serine/threonine-protein phosphatase with EF-hands vs. Ensembl Yeast
Match: PPH21 (Catalytic subunit of protein phosphatase 2A (PP2A); functionally redundant with Pph22p; methylated at C terminus; forms alternate complexes with several regulatory subunits; involved in signal transduction and regulation of mitosis; forms nuclear foci upon DNA replication stress; PPH21 has a paralog, PPH22, that arose from the whole genome duplication [Source:SGD;Acc:S000002292]) HSP 1 Score: 190.66 bits (483), Expect = 1.307e-54 Identity = 110/309 (35.60%), Postives = 169/309 (54.69%), Query Frame = 1 Query: 589 SINQVTALIESFRKEQILHARYLLELLDHTRNLLKTKPNVSQASTSISKRVTICGDLHGQLDDLVTIF-YKNKFPDTSNPYIINGDFVDRGSHSVEIAAILFSFFLLYPQSVFLNRGNHEDHVMNYRYGFVKEIQIKYKSNANKIVRFFADIFSWLPLMTIIDNSILVCHGGISAML-NLDVIEKLDRHKFLSVLQAPVEDIKNENKEEEWMQILDLLWSDPRSKPGCSVNQYRGGGCYFGPDITNDILKKYNLSLLIRSHECKIDGYEWCHENKVVTLFSASNYYKQGSNKGAFLRIDNEHNKQFFQY 1509 +INQ+ IE K + L + L ++L+ + NV I+ VTICGD+HGQ DL+ +F PDT+ Y+ GD+VDRG +SVE + L + + YP + + RGNHE + YGF E KY S AN + + F D+F + P+ ++DN I HGG+S M+ +D + +L+R ++++ +E + DLLWSDP + G ++ RG G FG D++ +LSL+ R+H+ ++GY W H+ VVT+FSA NY + N+ A + +D HN+QF QY Sbjct: 66 NINQLDQWIEHLSKCEPLSEDDVARLCKMAVDVLQFEENVK----PINVPVTICGDVHGQFHDLLELFKIGGPCPDTN--YLFMGDYVDRGYYSVETVSYLVAMKVRYPHRITILRGNHESRQITQVYGFYDECLRKYGS-AN-VWKMFTDLFDYFPITALVDNKIFCLHGGLSPMIETIDQVRELNR----------IQEVPHEGP------MCDLLWSDPDDRGGWGISP-RGAGFTFGQDVSEQFNHTNDLSLIARAHQLVMEGYAWSHQQNVVTIFSAPNYCYRCGNQAAIMEVDENHNRQFLQY 349
BLAST of Serine/threonine-protein phosphatase with EF-hands vs. Ensembl Yeast
Match: PPH22 (Catalytic subunit of protein phosphatase 2A (PP2A); functionally redundant with Pph21p; methylated at C terminus; forms alternate complexes with several regulatory subunits; involved in signal transduction and regulation of mitosis; protein abundance increases in response to DNA replication stress; dephosphorylates Tel1p/Mec1p-phosphorylated Cdc13p to promote telomerase release from telomeres at G2/M; PPH22 has a paralog, PPH21, that arose from the whole genome duplication [Source:SGD;Acc:S000002347]) HSP 1 Score: 189.889 bits (481), Expect = 2.993e-54 Identity = 111/309 (35.92%), Postives = 168/309 (54.37%), Query Frame = 1 Query: 589 SINQVTALIESFRKEQILHARYLLELLDHTRNLLKTKPNVSQASTSISKRVTICGDLHGQLDDLVTIF-YKNKFPDTSNPYIINGDFVDRGSHSVEIAAILFSFFLLYPQSVFLNRGNHEDHVMNYRYGFVKEIQIKYKSNANKIVRFFADIFSWLPLMTIIDNSILVCHGGISAML-NLDVIEKLDRHKFLSVLQAPVEDIKNENKEEEWMQILDLLWSDPRSKPGCSVNQYRGGGCYFGPDITNDILKKYNLSLLIRSHECKIDGYEWCHENKVVTLFSASNYYKQGSNKGAFLRIDNEHNKQFFQY 1509 +INQ+ IE K + L + L ++L+ + NV I+ VTICGD+HGQ DL+ +F PDT+ Y+ GD+VDRG +SVE + L + + YP + + RGNHE + YGF E KY S AN + + F D+F + P+ ++DN I HGG+S M+ +D + L+R ++++ +E + DLLWSDP + G ++ RG G FG DI+ +LSL+ R+H+ ++GY W H+ VVT+FSA NY + N+ A + +D HN+QF QY Sbjct: 74 NINQLDQWIEHLSKCEPLSEDDVARLCKMAVDVLQFEENVK----PINVPVTICGDVHGQFHDLLELFKIGGPCPDTN--YLFMGDYVDRGYYSVETVSYLVAMKVRYPHRITILRGNHESRQITQVYGFYDECLRKYGS-AN-VWKMFTDLFDYFPVTALVDNKIFCLHGGLSPMIETIDQVRDLNR----------IQEVPHEGP------MCDLLWSDPDDRGGWGISP-RGAGFTFGQDISEQFNHTNDLSLIARAHQLVMEGYSWSHQQNVVTIFSAPNYCYRCGNQAAIMEVDENHNRQFLQY 357
BLAST of Serine/threonine-protein phosphatase with EF-hands vs. Ensembl Yeast
Match: PPT1 (Protein serine/threonine phosphatase; regulates Hsp90 chaperone by affecting its ATPase and cochaperone binding activities; has similarity to human phosphatase PP5; present in both the nucleus and cytoplasm; expressed during logarithmic growth [Source:SGD;Acc:S000003355]) HSP 1 Score: 178.718 bits (452), Expect = 5.572e-49 Identity = 105/314 (33.44%), Postives = 166/314 (52.87%), Query Frame = 1 Query: 556 TYKGAKLTFPLSINQVTALIES-FRKEQILHARYLLELLDHTRNLLKTKPNVSQA--STSISKRVTICGDLHGQLDDLVTIFYKNKFPDTSNPYIINGDFVDRGSHSVEIAAILFSFFLLYPQSVFLNRGNHEDHVMNYRYGFVKEIQIKYKSNANKIVRFFADIFSWLPLMTIIDNSILVCHGGISAMLNLDVIEKLDRHKFLSVLQAPVEDIKNENKEEEWMQILDLLWSDPRSKPGCSVNQYRGGGCYFGPDITNDILKKYNLSLLIRSHECKIDGYEWCHENKVVTLFSASNYYKQGSNKGAFLRIDNEH 1488 +KGAK+ +S ++ ++ F K + L +Y+ ++ H L + +P++ + +++ ++++CGD HGQ D++ +F K + Y+ NGDFVDRGS S E+A + + +L+P + FLNRGNHE MN YGF E + KY + +I FA F LPL T+I+N LV HGG+ + D L K + P D ++LLW+DP+ G +Q RG G FGPDIT+ L+ L + RSHE ++ G ++ + K++T+FSA NY N G + + H Sbjct: 181 AFKGAKIK-NMSQEFISKMVNDLFLKGKYLPKKYVAAIISHADTLFRQEPSMVELENNSTPDVKISVCGDTHGQFYDVLNLFRKFGKVGPKHTYLFNGDFVDRGSWSCEVALLFYCLKILHPNNFFLNRGNHESDNMNKIYGFEDECKYKY---SQRIFNMFAQSFESLPLATLINNDYLVMHGGLPS----DPSATLSDFKNIDRFAQPPRD----------GAFMELLWADPQEANGMGPSQ-RGLGHAFGPDITDRFLRNNKLRKIFRSHELRMGGVQFEQKGKLMTVFSAPNYCDSQGNLGGVIHVVPGH 475
BLAST of Serine/threonine-protein phosphatase with EF-hands vs. Ensembl Yeast
Match: PPH3 (Catalytic subunit of protein phosphatase PP4 complex; Pph3p and Psy2p form active complex, Psy4p may provide substrate specificity; regulates recovery from the DNA damage checkpoint, the gene conversion- and single-strand annealing-mediated pathways of meiotic double-strand break repair and efficient Non-Homologous End-Joining (NHEJ) pathway; involved in activation of Gln3p to alleviate nitrogen catabolite repression; Pph3p and Psy2p localize to foci on meiotic chromosomes [Source:SGD;Acc:S000002482]) HSP 1 Score: 166.777 bits (421), Expect = 8.516e-47 Identity = 109/298 (36.58%), Postives = 163/298 (54.70%), Query Frame = 1 Query: 610 LIESFRKEQILHARYLLELLDHTRNLLKTKPNVSQASTSISKRVTICGDLHGQLDDLVTIFYKNKFPDTSNPYIINGDFVDRGSHSVEIAAILFSFFLLYPQSVFLNRGNHEDHVMNYRYGFVKEIQIKYKSNANKIVRFFADIFSWLPLMTIIDNSILVCHGGISA-MLNLDVIEKLDRHKFLSVLQAPVEDIKNENKEEEWMQILDLLWSDPRSKPGCSVNQYRGGGCYFGPDITNDILKKYNLSLLIRSHECKIDGYEWCHENKVVTLFSASNYYKQGSNKGAFLRIDNEHNKQF 1500 +I S R + + + L +++ LL + NV+Q T VTICGD+HGQL DL+T+F K+ + + YI GDFVDRG +S+E +L + L YP + L RGNHE + YGF E+ KY N+N + R+ ++F +L L II+NSI HGG+S M +D I +DR K E E M DLLWSDP S++ RG G FG + L+K N+ L+ R+H+ ++GY+ + +VT++SA NY + N A L+ID++ N+++ Sbjct: 7 IIASLRDGKHIPEETVFRLCLNSQELLMNEGNVTQVDTP----VTICGDIHGQLHDLLTLFEKSGGVEKTR-YIFLGDFVDRGFYSLESFLLLLCYKLRYPDRITLIRGNHETRQITKVYGFYDEVVRKY-GNSN-VWRYCCEVFDYLSLGAIINNSIFCVHGGLSPDMTTVDEIRTIDR--------------KQEVPHEGAM--CDLLWSDPEDVDTWSLSP-RGAGFLFGKREVDQFLEKNNVELIARAHQLVMEGYKEMFDGGLVTVWSAPNYCYRCGNVAAVLKIDDDLNREY 280
BLAST of Serine/threonine-protein phosphatase with EF-hands vs. Ensembl Yeast
Match: GLC7 (Type 1 S/T protein phosphatase (PP1) catalytic subunit; involved in glycogen metabolism, sporulation and mitotic progression; interacts with multiple regulatory subunits; regulates actomyosin ring formation; subunit of CPF; recruited to mating projections by Afr1p interaction; regulates nucleocytoplasmic shuttling of Hxk2p; import into the nucleus is inhibited during spindle assembly checkpoint arrest; involved in dephosphorylating Rps6a/b and Bnr1p [Source:SGD;Acc:S000000935]) HSP 1 Score: 160.614 bits (405), Expect = 1.780e-44 Identity = 97/248 (39.11%), Postives = 140/248 (56.45%), Query Frame = 1 Query: 739 VTICGDLHGQLDDLVTIFYKNKFPDTSNPYIINGDFVDRGSHSVEIAAILFSFFLLYPQSVFLNRGNHEDHVMNYRYGFVKEIQIKYKSNANKIVRFFADIFSWLPLMTIIDNSILVCHGGISAMLNLDVIEKLDRHKFLSVLQAPVEDIKNENKEEEWMQILDLLWSDP-RSKPGCSVNQYRGGGCYFGPDITNDILKKYNLSLLIRSHECKIDGYEWCHENKVVTLFSASNYYKQGSNKGAFLRID 1479 + ICGD+HGQ DL+ +F FP SN Y+ GD+VDRG S+E +L ++ + YP++ F+ RGNHE +N YGF E + +Y K+ + F D F+ LP+ IID I HGG+S LN +E++ R + P DI + + DLLWSDP + G S N RG FGPD+ N L+K ++ L+ R+H+ DGYE+ + ++VTLFSA NY + N GA + +D Sbjct: 58 IKICGDIHGQYYDLLRLFEYGGFPPESN-YLFLGDYVDRGKQSLETICLLLAYKIKYPENFFILRGNHECASINRIYGFYDECKRRYNI---KLWKTFTDCFNCLPIAAIIDEKIFCMHGGLSPDLN--SMEQIRR------VMRPT-DIPDVG------LLCDLLWSDPDKDIVGWSEND-RGVSFTFGPDVVNRFLQKQDMELICRAHQVVEDGYEFFSKRQLVTLFSAPNYCGEFDNAGAMMSVD 285
BLAST of Serine/threonine-protein phosphatase with EF-hands vs. Ensembl Nematostella
Match: EDO47034 (Serine/threonine-protein phosphatase [Source:UniProtKB/TrEMBL;Acc:A7RNB7]) HSP 1 Score: 665.611 bits (1716), Expect = 0.000e+0 Identity = 322/662 (48.64%), Postives = 448/662 (67.67%), Query Frame = 1 Query: 112 MGCAQSNSPKHEYDNIYNSPKENIIENSKKTSHHVKKIYSTGDTGPISIKAAILIQNWYRRYRAKLEAKRRYTWMIYQSIEYSGEQDQLKLQSFFNDLLSLT---NKGQECDSEVIEALSKTHVLKTAPTVSDEDRDLQYLTKIEQIVVEPTYKGAKLTFPLSINQVTALIESFRKEQILHARYLLELLDHTRNLLKTKPNVSQASTSISKRVTICGDLHGQLDDLVTIFYKNKFPDTSNPYIINGDFVDRGSHSVEIAAILFSFFLLYPQSVFLNRGNHEDHVMNYRYGFVKEIQIKYKSNANKIVRFFADIFSWLPLMTIIDNSILVCHGGISAMLNLDVIEKLDRHKFLSVLQAP--VEDIKNENKEEEWMQILDLLWSDPRSKPGCSVNQYRGGGCYFGPDITNDILKKYNLSLLIRSHECKIDGYEWCHENKVVTLFSASNYYKQGSNKGAFLRIDNEHNKQFFQYTTHKKNQKHLTLIQSVNQIEESALRDLKGKILAFKNELAEEFIQKDVNNRGVIELQEWCTVMENVLKLPLPWRTLRPHLVKLSKEGKVEYSSIFEAQQVDNKFLMIAGTMTEELYKNKENLETIFRIMDKDNSGHISLSEFRDACKLLHRHTNRNVSEEAIEDLAKCLDINKDGQIDFNEFLEAFRIVDSS 2082 MGC S EYD NS + S+K ++++A+LIQNW+RRYRA+LEA+RR TW I+QSIEYSGEQDQLKL +FF D+L+ N G + + + LS+ + S L+ T I VEPTY G + P+++ V +IE + +++HA+Y+L +L R + PNV + +T I+K++TICGDLHG+LDDL IF+KN P NPYI NGD VDRG S+EI ILF+F +LYP V++NRGNHEDH+MN RYGFVKE+ KYK +A+KI+R F DIF WLPL TI++N I V HGGIS + +LD+IE++DRHK++SVL+ P V+D + + +EW Q+LDLLWSDP+ PGC N +RGGGCYFGPD+T+ +L+K+N LL+RSHECK +GYE+ H KV+T+FSASNYY+QGSN+GA+++I + F QY + +KHLTL Q V +EESA+R+LK K+ A K+ L E F ++D + G + +W +E+ L L +PW LR L ++ +GKV+Y S E ++ K ++TE LY+N+ NLETIFR+MDKDNSGH+S+ EF+ +C+LL++H+ + E++I+DLA+ +D++KDG IDFNEFLEAFR+VD S Sbjct: 1 MGCGTSVDAYKEYDGHKNSLS---LSKSEK-----------------ALRSAVLIQNWFRRYRARLEARRRCTWKIFQSIEYSGEQDQLKLFNFFTDMLTHVQPDNTGASRANIIEDTLSRNGSASST--SSKSSTTLEAATDPSDIKVEPTYTGHVVKLPITLMSVRNIIEQCKLNKLVHAKYVLLILREARERFRALPNVIRVTTRIAKQMTICGDLHGKLDDLFMIFHKNGLPSPENPYIFNGDLVDRGPRSIEICIILFAFTILYPNGVYINRGNHEDHIMNLRYGFVKEVMDKYKDHASKIIRLFEDIFGWLPLATIVNNKIFVAHGGISNITDLDIIERIDRHKYVSVLKPPNIVKDNPSLSSLKEWRQVLDLLWSDPKPTPGCKPNTFRGGGCYFGPDVTSQVLRKHNFELLVRSHECKYEGYEYMHNKKVITIFSASNYYEQGSNRGAYMKIGPDMTPYFVQYQV-SRTKKHLTLKQRVGIVEESAIRELKEKLYANKSALMEAFTKRDEQHTGYLTCSQWAAAIESTLHLDVPWNMLRHQLAYVAPDGKVDYRSCLEQYAIEGKTKKNGPSITEALYRNRSNLETIFRLMDKDNSGHVSMEEFQASCRLLNQHSETEIPEDSIQDLARSIDMDKDGYIDFNEFLEAFRLVDVS 639
BLAST of Serine/threonine-protein phosphatase with EF-hands vs. Ensembl Nematostella
Match: EDO29759 (Serine/threonine-protein phosphatase [Source:UniProtKB/TrEMBL;Acc:A7T2Q5]) HSP 1 Score: 184.882 bits (468), Expect = 7.387e-53 Identity = 107/312 (34.29%), Postives = 169/312 (54.17%), Query Frame = 1 Query: 631 EQILHARYLLE-----LLDHTRNLLKTKPNVSQASTSISKRVTICGDLHGQLDDLVTIF-YKNKFPDTSNPYIINGDFVDRGSHSVEIAAILFSFFLLYPQSVFLNRGNHEDHVMNYRYGFVKEIQIKYKSNANKIVRFFADIFSWLPLMTIIDNSILVCHGGISAMLN-LDVIEKLDRHKFLSVLQAPVEDIKNENKEEEWMQILDLLWSDPRSKPGCSVNQYRGGGCYFGPDITNDILKKYNLSLLIRSHECKIDGYEWCHENKVVTLFSASNYYKQGSNKGAFLRIDNEHNKQFFQY-TTHKKNQKHLT 1542 EQ++ + L E L + + +L + NV + VT+CGD+HGQ DL+ +F K PDT+ Y+ GD+VDRG +SVE +L + + +P + + RGNHE + YGF E KY NA+ + ++F D+F +LPL ++DN I HGG+S ++ LD I LDR ++++ +E + DLLWSDP + G ++ RG G FG DI+ L+L+ R+H+ ++GY WCH+ VVT+FSA NY + N+ A + +D+ F Q+ ++ + H+T Sbjct: 16 EQLMECKQLTEAQVKTLCEKAKEILSKESNVQEVKCP----VTVCGDVHGQFHDLMELFRIGGKSPDTN--YLFMGDYVDRGYYSVETVTLLVTLKVRFPHRICILRGNHESRQITQVYGFYDECLRKY-GNAS-VWKYFTDLFDYLPLTALVDNQIFCLHGGLSPSIDTLDHIRALDR----------IQEVPHEGP------MCDLLWSDPDDRGGWGISP-RGAGYTFGQDISETFNHTNGLTLITRAHQLVMEGYNWCHDRNVVTIFSAPNYCYRCGNQAAIMELDDALKYSFLQFDPAPRRGEPHVT 302
BLAST of Serine/threonine-protein phosphatase with EF-hands vs. Ensembl Nematostella
Match: EDO44648 (Serine/threonine-protein phosphatase [Source:UniProtKB/TrEMBL;Acc:A7RVJ0]) HSP 1 Score: 163.31 bits (412), Expect = 8.901e-45 Identity = 96/248 (38.71%), Postives = 140/248 (56.45%), Query Frame = 1 Query: 739 VTICGDLHGQLDDLVTIFYKNKFPDTSNPYIINGDFVDRGSHSVEIAAILFSFFLLYPQSVFLNRGNHEDHVMNYRYGFVKEIQIKYKSNANKIVRFFADIFSWLPLMTIIDNSILVCHGGISAMLNLDVIEKLDRHKFLSVLQAPVEDIKNENKEEEWMQILDLLWSDP-RSKPGCSVNQYRGGGCYFGPDITNDILKKYNLSLLIRSHECKIDGYEWCHENKVVTLFSASNYYKQGSNKGAFLRID 1479 + ICGD+HGQ DL+ +F FP SN Y+ GD+VDRG S+E +L ++ + YP++ FL RGNHE +N YGF E + +Y K+ + F D F+ LP+ I+D I CHGG+S +L +E++ R + P D+ ++ + DLLWSDP + G N RG FGPDI L K++L L+ R+H+ DGYE+ + ++VTLFSA NY + N GA + +D Sbjct: 59 LKICGDIHGQYYDLLRLFEYGGFPPESN-YLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNI---KLWKTFTDCFNCLPVAAILDEKIFCCHGGLSP--DLQSMEQIRR------IMRPT-DVPDQG------LLCDLLWSDPDKDVQGWGEND-RGVSFTFGPDIVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVD 286
BLAST of Serine/threonine-protein phosphatase with EF-hands vs. Ensembl Nematostella
Match: EDO49936 (Serine/threonine-protein phosphatase [Source:UniProtKB/TrEMBL;Acc:A7RFC7]) HSP 1 Score: 159.844 bits (403), Expect = 8.235e-44 Identity = 103/298 (34.56%), Postives = 151/298 (50.67%), Query Frame = 1 Query: 613 IESFRKEQILHARYLLELLDHTRNLLKTKPNVSQASTSISKRVTICGDLHGQLDDLVTIF-YKNKFPDTSNPYIINGDFVDRGSHSVEIAAILFSFFLLYPQSVFLNRGNHEDHVMNYRYGFVKEIQIKYKSNANKIVRFFADIFSWLPLMTIIDNSILVCHGGISAMLN-LDVIEKLDRHKFLSVLQAPVEDIKNENKEEEWMQILDLLWSDPRSKPGCSVNQYRGGGCYFGPDITNDILKKYNLSLLIRSHECKIDGYEWCHENKVVTLFSASNYYKQGSNKGAFLRIDNEHNKQF 1500 IE R +++ + + +L R +L + NV + + VT+CGD+HGQ DL +F PDT+ Y+ GDFVDRG +SVE +L + + YP + L RGNHE + YGF E KY S + R+ A+IF +L L IIDN + HGG+S ++ LD I +DR K E + M DLLWSDP G V+ RG G FG D+ ++ L+ R+H+ ++GY+W V+T++SA NY + N A L +D ++F Sbjct: 11 IEKLRNCELITEKEVKQLCAKAREILVEESNVQRVDSP----VTVCGDIHGQFYDLKELFKVGGDVPDTN--YLFMGDFVDRGFYSVETFLLLLALKVRYPDRITLIRGNHESRQITQVYGFYDECLKKYGSIT--VWRYCAEIFDYLSLSAIIDNRVFCVHGGLSPSISTLDQIRSIDR--------------KQEVPHDGPM--CDLLWSDPEDIQGWGVSP-RGAGYLFGSDVVAQYNAANDIDLICRAHQLVMEGYKWHFNETVLTVWSAPNYCYRCGNVAAILELDEHLKREF 283
BLAST of Serine/threonine-protein phosphatase with EF-hands vs. Ensembl Nematostella
Match: EDO36272 (Serine/threonine-protein phosphatase [Source:UniProtKB/TrEMBL;Acc:A7SJ38]) HSP 1 Score: 129.798 bits (325), Expect = 4.347e-32 Identity = 86/266 (32.33%), Postives = 132/266 (49.62%), Query Frame = 1 Query: 727 ISKRVTICGDLHGQLDDLVTIFYKNKFPDTSNPYIINGDFVDRGSHSVEIAAILFSFFLLYPQSVFLNRGNHEDHVMNYRYGFVKEIQIKYKSNANKIVRFFADIFSWLPLMTIIDNSILVCHGGISAMLN-LDVIEKLDRHKFLSVLQAPVEDIKNENKEEEWMQILDLLWSDPRSKPG-------CSVNQYRGGGCYFGPDITNDILKKYNLSLLIRSHECKIDGYEWCHENK------VVTLFSASNYYKQGSNKGAFLRIDN 1482 + +T+CGD+HGQ DLV +F P T+ Y+ GD+VDRG S+E L++ LY ++FL RGNHE + + F E +IKY + + + F LPL +++ L HGG+S ++ LD ++KLDR K + + + DLLWSDP G S N RG ++ T + L+ NL +IR+HE + GY +++ ++T+FSA NY +NK A L+ +N Sbjct: 59 VDAPITVCGDIHGQFYDLVKLFEVGGSPATTR-YLFLGDYVDRGYFSIECVLYLWTLKCLYTNTLFLLRGNHECRHLTEYFTFKTECKIKY---SEAVYDACMESFDCLPLAALMNQQFLCVHGGLSPEIHTLDDVKKLDRFK----------------EPPAFGPMCDLLWSDPLEDYGNEKTSEHFSHNTVRGCSYFYSYPATCEFLQNNNLLSIIRAHEAQDAGYRMYRKSQATGFPSLITIFSAPNYLDVYNNKAAVLKYEN 304
BLAST of Serine/threonine-protein phosphatase with EF-hands vs. Ensembl Medaka
Match: ppef1 (protein phosphatase with EF-hand domain 1 [Source:NCBI gene;Acc:101174574]) HSP 1 Score: 318.931 bits (816), Expect = 1.371e-97 Identity = 150/311 (48.23%), Postives = 206/311 (66.24%), Query Frame = 1 Query: 1162 VLQAPVED-------IKNENKEEEWMQILDLLWSDPRSKPGCSVNQYRGGGCYFGPDITNDILKKYNLSLLIRSHECKIDGYEWCHENKVVTLFSASNYYKQGSNKGAFLRIDNEHNKQFFQYTTHKKNQKHLTLIQSVNQIEESALRDLKGKILAFKNELAEEFIQKDVNNRGVIELQEWCTVMENVLKLPLPWRTLRPHLVKLSKEGKVEYSSIFEAQQVDNKFLMIAGTMTEELYKNKENLETIFRIMDKDNSGHISLSEFRDACKLLHRHTNRNVSEEAIEDLAKCLDINKDGQIDFNEFLEAFRIV 2073 VLQ P D E+EW QI+D+LWSDP+++ GCS N +RGGGCYFGPD+T +L ++ L +LIRSHECK +GYE CH KV+T+FSASNYY++GSN+GA++++ E +F+QY + +K LTL Q + E SALR LK K+ A ++EL F Q D +N G + + EW V+E VL+L LPWRTLRPHL +L+ +G VEY S FE + + + E L++ + ++E IF I+DKD+SG IS+ EFR +L H + + AI+DLA+ +D NKDG IDF EFLEAFR+V Sbjct: 417 VLQVPYLDSLSSIPLPSPPQHEQEWKQIVDILWSDPKTQEGCSPNLFRGGGCYFGPDVTQKLLLQHGLQMLIRSHECKQEGYEICHGGKVITIFSASNYYEEGSNRGAYIKLGRELVPRFYQYQVSRITRK-LTLTQRIRAAEGSALRALKEKLFAHRSELVGSFQQYDPDNTGTVSVCEWAQVLECVLRLDLPWRTLRPHLARLASDGSVEYQSCFEDMEPGATLPKVTPNLAETLFRYRTDIEIIFNIIDKDHSGLISIEEFRHTWRLFSAHLGVAIDDRAIDDLARSIDFNKDGSIDFTEFLEAFRVV 726 HSP 2 Score: 293.123 bits (749), Expect = 6.132e-88 Identity = 149/313 (47.60%), Postives = 213/313 (68.05%), Query Frame = 1 Query: 250 ISIKAAILIQNWYRRYRAKLEAKRRYTWMIYQSIEYSGEQDQLKLQSFFNDLL----SLTNKGQECDSEVIEALSKTHVLKTAPTVSDEDRDLQYLTKIEQIVVEPTYKGAKLTFPLSINQVTALIESFRKEQILHARYLLELLDHTRNLLKTKPNVSQASTSISKRVTICGDLHGQLDDLVTIFYKNKFPDTSNPYIINGDFVDRGSHSVEIAAILFSFFLLYPQSVFLNRGNHEDHVMNYRYGFVKEIQIKYKSNANKIVRFFADIFSWLPLMTIIDNSILVCHGGISAMLNLDVIEKLDRHKFLSVLQAP 1176 ++IKAA+LIQ WYRRY A+LE +RRYTW I+QSIEY+GEQDQL+L SFF+ +L L+ G + +++++ + + DR++ Y + V +Y G +++FPL ++ L+ +F+++QILHARY+L+LL + LLK PN++ STS +K +TICGDLHG LDDL+ IFYKN P PY+ NGDFVDRG SVE+ +LF++FLLYP + LNRGNHED +MN RYGF KE+ KYK + +I++ F D+FS LP+ T+ID +L+ HGGIS +L+++ + RHK S L+ P Sbjct: 29 LTIKAAVLIQRWYRRYMARLEMRRRYTWNIFQSIEYAGEQDQLQLSSFFSFMLDNFTQLSGNGPDLITQLLDPVVDPWL----------DREICY----NLVPVPDSYTGPRISFPLGVSDTNTLLSAFKEQQILHARYVLQLLYEAKKLLKQMPNINHLSTSYTKDITICGDLHGHLDDLLLIFYKNGLPSAETPYVFNGDFVDRGKKSVEVVIMLFAYFLLYPDYMHLNRGNHEDPIMNLRYGFTKEVMQKYKIHGREILQLFQDVFSLLPIATVIDGKVLIVHGGISDQTDLNLLSSIKRHKVKSALRFP 327
BLAST of Serine/threonine-protein phosphatase with EF-hands vs. Ensembl Medaka
Match: PPEF2 (serine/threonine-protein phosphatase with EF-hands 2 [Source:NCBI gene;Acc:101170112]) HSP 1 Score: 300.056 bits (767), Expect = 1.046e-90 Identity = 155/322 (48.14%), Postives = 213/322 (66.15%), Query Frame = 1 Query: 253 SIKAAILIQNWYRRYRAKLEAKRRYTWMIYQSIEYSGEQDQLKLQSFFNDLLSLTNKGQECDSEVIEALSKTHVLKTAPTVSDEDRDLQYLTKIEQIVVEPTYKGAKLTFPLSINQVTALIESFRKEQILHARYLLELLDHTRNLLKTKPNVSQASTSISKRVTICGDLHGQLDDLVTIFYKNKFPDTSNPYIINGDFVDRGSHSVEIAAILFSFFLLYPQSVFLNRGNHEDHVMNYRYGFVKEIQIKYKSNANKIVRFFADIFSWLPLMTIIDNSILVCHGGISAMLNLDVIEKLDRHKFLSVLQAP--VEDIKNENKEEE 1212 +I+AA+LIQ WYR+Y A+LE +RR TW I+QSIEY+GEQDQ+KL SFF L+ + + +H+ D + + + K I V +Y G LTFP++ V+ L+E+F+ +Q LHARY+L++L T LL+ PN++ S S +K +TICGDLHGQL+DL+ IFYKN P + PYI NGDFVDRG S+EI ILF F L+YP + LNRGNHEDH++N RYGF KEI KY+ + KI++ IFSWLPL T+I++ +LV HGGIS +L V+ ++DRH+++SVL+ P V N NK E+ Sbjct: 25 AIRAALLIQRWYRQYVARLEMRRRCTWNIFQSIEYAGEQDQIKLYSFFGFLMDHFTPASSERNLI------SHIFHENEICRDTEWERYFCYK--DIEVPDSYTGPHLTFPMTFCGVSKLVEAFKHKQQLHARYVLQILGETWRLLRILPNINYVSVSQTKEITICGDLHGQLEDLLLIFYKNGLPSSEKPYIFNGDFVDRGKSSLEILLILFGFLLVYPNDLHLNRGNHEDHIVNLRYGFTKEILGKYRVHGKKILKLLQKIFSWLPLATVINDKVLVVHGGISNSTDLCVVSRVDRHRYVSVLRPPKTVHQTLNGNKNED 338 HSP 2 Score: 288.886 bits (738), Expect = 1.534e-86 Identity = 142/292 (48.63%), Postives = 193/292 (66.10%), Query Frame = 1 Query: 1210 EWMQILDLLWSDPRSKPGCSVNQYRGGGCYFGPDITNDILKKYNLSLLIRSHECKIDGYEWCHENKVVTLFSASNYYKQGSNKGAFLRIDNEHNKQFFQYTTHKKNQKHLTLIQSVNQIEESALRDLKGKILAFKNELAEEFIQKDVNNRGVIELQEWCTVMENVLKLPLPWRTLRPHLVKLSKEGKVEYSSIFEAQQVDNKFLMIAGT-MTEELYKNKENLETIFRIMDKDNSGHISLSEFRDACKLLHRHTNRNVSEEAIEDLAKCLDINKDGQIDFNEFLEAFRIVDSS 2082 +W QI++LLWSDP + GC N+ RGGGCY+GPD+T ++L ++NL LLIRSHECK DGYE+CH +V+T+FSASNYY+ GSN+GA++R+ + QY + + LTL QSV E SALR L+ ++ K++L + + D + G I ++ W + E+VLKL LPWR LR LV + G V+Y + + L ++ T + E +YKN NLETIFRI+D D+SG ISL EFR KLL H +S++AI DLA +D NKDG ID NEF+EAFR+VD S Sbjct: 424 DWKQIVNLLWSDPMPQNGCISNEVRGGGCYWGPDVTEEVLGRHNLQLLIRSHECKQDGYEFCHNRRVLTIFSASNYYEVGSNRGAYIRMGADLVPHLIQYQA-SRTCRELTLRQSVGWTERSALRALREQLFVHKSDLIRAYQEFDPHQTGKISMRHWASATESVLKLGLPWRVLRSQLVSRTHYGMVDYQQWIKELSITEPKLEVSDTSILETMYKNHSNLETIFRIIDTDHSGLISLEEFRQTWKLLSSHLKMEISDKAIADLAHSIDFNKDGSIDINEFMEAFRLVDLS 714
BLAST of Serine/threonine-protein phosphatase with EF-hands vs. Ensembl Medaka
Match: ENSORLT00000036394.1 (serine/threonine-protein phosphatase with EF-hands 2-like [Source:NCBI gene;Acc:101171918]) HSP 1 Score: 298.901 bits (764), Expect = 4.136e-90 Identity = 159/334 (47.60%), Postives = 216/334 (64.67%), Query Frame = 1 Query: 253 SIKAAILIQNWYRRYRAKLEAKRRYTWMIYQSIEYSGEQDQLKLQSFFNDLL-SLTNKGQECDSEVIEALSKTHVLKTAPTVSDEDRDLQYLTKIEQIVVEPTYKGAKLTFPLSINQVTALIESFRKEQILHARYLLELLDHTRNLLKTKPNVSQASTSISKRVTICGDLHGQLDDLVTIFYKNKFPDTSNPYIINGDFVDRGSHSVEIAAILFSFFLLYPQSVFLNRGNHEDHVMNYRYGFVKEIQIKYKSNANKIVRFFADIFSWLPLMTIIDNSILVCHGGISAMLNLDVIEKLDRHKFLSVLQAPVEDIKNENKEEEWMQILDLLWSDPR 1251 +I+AA+LIQ WYR+Y A+ E +RRYTW I+QSIEYSGEQ Q+KL +F L+ + T E +I +H+ + D + + + K I V Y G LTFPL++ Q L+++FR ++ LH+RY+L+LL T LL+ PN+++ ST SK VTICGDLHGQL+DL+ IFYKN P PY+ NGDFVDRG S+EI ILFSF L+YP V+LNRGNHEDH++N RYGF KE+ KY+ + +I++ IFSWLPL T+ID +LV HGGIS +L V+ KLDRH ++S L+ P + ++ + M I D W R Sbjct: 18 AIRAAVLIQRWYRQYVARTEMRRRYTWNIFQSIEYSGEQAQIKLYNFLGYLMDNFTPSSSE--RNLI-----SHIFRENDICRDAEWERYFCYK--NIEVPEVYSGPHLTFPLTLEQAIGLLDAFRNKKQLHSRYVLQLLLETWRLLRMLPNINRISTCHSKEVTICGDLHGQLEDLLLIFYKNGMPSLEKPYVFNGDFVDRGKDSIEILLILFSFLLIYPSDVYLNRGNHEDHIINLRYGFTKEVLTKYRVHGKRILKLLQKIFSWLPLATVIDQKVLVLHGGISDTTDLAVLAKLDRHSYVSALRPPKKRNQSLSGLSMDMDIGDEGWGTSR 342 HSP 2 Score: 282.722 bits (722), Expect = 4.911e-84 Identity = 137/307 (44.63%), Postives = 197/307 (64.17%), Query Frame = 1 Query: 1162 VLQAPVEDIKNENKEEEWMQILDLLWSDPRSKPGCSVNQYRGGGCYFGPDITNDILKKYNLSLLIRSHECKIDGYEWCHENKVVTLFSASNYYKQGSNKGAFLRIDNEHNKQFFQYTTHKKNQKHLTLIQSVNQIEESALRDLKGKILAFKNELAEEFIQKDVNNRGVIELQEWCTVMENVLKLPLPWRTLRPHLVKL-SKEGKVEYSSIFEAQQVDNKFL-MIAGTMTEELYKNKENLETIFRIMDKDNSGHISLSEFRDACKLLHRHTNRNVSEEAIEDLAKCLDINKDGQIDFNEFLEAFRIVD 2076 L + ++++N EEW QILDLLWSDP ++ GC N+ RGGGCY+GPDIT D L ++N+ L+IRSHECK +GYE+CH +V+TLFSASNYY GSN+GA++++ + QY + LT QS+ + E SAL+ L+ ++ A K++L F D N G++ L +W +E+V+ L LPWR LR LV +G ++Y++ F + I T+ E LY+++ LETIFRI+D DNSG IS+ +FR KLL + +++EAI DLA +D N+DG ID +EF+EAFR+ D Sbjct: 403 ALNVSTDSVRSDNSNEEWRQILDLLWSDPMTQNGCKPNEVRGGGCYWGPDITEDFLNRHNMQLIIRSHECKQEGYEFCHNRRVLTLFSASNYYDVGSNRGAYVKMGPDLEPYVIQYQASSMT-RELTAKQSIGRTERSALKVLREQLFAHKSDLICAFRGFDTENAGLVSLSDWACAVESVMHLNLPWRMLRCQLVTCKGSDGMIDYNAWFHELAIKGPNTDHIEQTLLETLYRHRSTLETIFRIVDTDNSGFISMEDFRQTWKLLSVYLKMEITDEAISDLAVTIDSNQDGSIDIDEFMEAFRLTD 708
BLAST of Serine/threonine-protein phosphatase with EF-hands vs. Ensembl Medaka
Match: ENSORLT00000000429.2 (serine/threonine-protein phosphatase with EF-hands 2-like [Source:NCBI gene;Acc:101171918]) HSP 1 Score: 282.337 bits (721), Expect = 2.627e-84 Identity = 137/307 (44.63%), Postives = 197/307 (64.17%), Query Frame = 1 Query: 1162 VLQAPVEDIKNENKEEEWMQILDLLWSDPRSKPGCSVNQYRGGGCYFGPDITNDILKKYNLSLLIRSHECKIDGYEWCHENKVVTLFSASNYYKQGSNKGAFLRIDNEHNKQFFQYTTHKKNQKHLTLIQSVNQIEESALRDLKGKILAFKNELAEEFIQKDVNNRGVIELQEWCTVMENVLKLPLPWRTLRPHLVKL-SKEGKVEYSSIFEAQQVDNKFL-MIAGTMTEELYKNKENLETIFRIMDKDNSGHISLSEFRDACKLLHRHTNRNVSEEAIEDLAKCLDINKDGQIDFNEFLEAFRIVD 2076 L + ++++N EEW QILDLLWSDP ++ GC N+ RGGGCY+GPDIT D L ++N+ L+IRSHECK +GYE+CH +V+TLFSASNYY GSN+GA++++ + QY + LT QS+ + E SAL+ L+ ++ A K++L F D N G++ L +W +E+V+ L LPWR LR LV +G ++Y++ F + I T+ E LY+++ LETIFRI+D DNSG IS+ +FR KLL + +++EAI DLA +D N+DG ID +EF+EAFR+ D Sbjct: 366 ALNVSTDSVRSDNSNEEWRQILDLLWSDPMTQNGCKPNEVRGGGCYWGPDITEDFLNRHNMQLIIRSHECKQEGYEFCHNRRVLTLFSASNYYDVGSNRGAYVKMGPDLEPYVIQYQASSMT-RELTAKQSIGRTERSALKVLREQLFAHKSDLICAFRGFDTENAGLVSLSDWACAVESVMHLNLPWRMLRCQLVTCKGSDGMIDYNAWFHELAIKGPNTDHIEQTLLETLYRHRSTLETIFRIVDTDNSGFISMEDFRQTWKLLSVYLKMEITDEAISDLAVTIDSNQDGSIDIDEFMEAFRLTD 671 HSP 2 Score: 271.166 bits (692), Expect = 4.509e-80 Identity = 147/313 (46.96%), Postives = 199/313 (63.58%), Query Frame = 1 Query: 316 KRRYTWMIYQSIEYSGEQDQLKLQSFFNDLL-SLTNKGQECDSEVIEALSKTHVLKTAPTVSDEDRDLQYLTKIEQIVVEPTYKGAKLTFPLSINQVTALIESFRKEQILHARYLLELLDHTRNLLKTKPNVSQASTSISKRVTICGDLHGQLDDLVTIFYKNKFPDTSNPYIINGDFVDRGSHSVEIAAILFSFFLLYPQSVFLNRGNHEDHVMNYRYGFVKEIQIKYKSNANKIVRFFADIFSWLPLMTIIDNSILVCHGGISAMLNLDVIEKLDRHKFLSVLQAPVEDIKNENKEEEWMQILDLLWSDPR 1251 +RRYTW I+QSIEYSGEQ Q+KL +F L+ + T E +I +H+ + D + + + K I V Y G LTFPL++ Q L+++FR ++ LH+RY+L+LL T LL+ PN+++ ST SK VTICGDLHGQL+DL+ IFYKN P PY+ NGDFVDRG S+EI ILFSF L+YP V+LNRGNHEDH++N RYGF KE+ KY+ + +I++ IFSWLPL T+ID +LV HGGIS +L V+ KLDRH ++S L+ P + ++ + M I D W R Sbjct: 2 RRRYTWNIFQSIEYSGEQAQIKLYNFLGYLMDNFTPSSSE--RNLI-----SHIFRENDICRDAEWERYFCYK--NIEVPEVYSGPHLTFPLTLEQAIGLLDAFRNKKQLHSRYVLQLLLETWRLLRMLPNINRISTCHSKEVTICGDLHGQLEDLLLIFYKNGMPSLEKPYVFNGDFVDRGKDSIEILLILFSFLLIYPSDVYLNRGNHEDHIINLRYGFTKEVLTKYRVHGKRILKLLQKIFSWLPLATVIDQKVLVLHGGISDTTDLAVLAKLDRHSYVSALRPPKKRNQSLSGLSMDMDIGDEGWGTSR 305
BLAST of Serine/threonine-protein phosphatase with EF-hands vs. Ensembl Medaka
Match: ppp5c (protein phosphatase 5 catalytic subunit [Source:NCBI gene;Acc:101158545]) HSP 1 Score: 243.817 bits (621), Expect = 5.660e-72 Identity = 131/332 (39.46%), Postives = 198/332 (59.64%), Query Frame = 1 Query: 532 IEQIVVEPTYKGAKL-TFPLSINQVTALIESFRKEQILHARYLLELLDHTRNLLKTKPNVSQASTSISKRVTICGDLHGQLDDLVTIFYKNKFPDTSNPYIINGDFVDRGSHSVEIAAILFSFFLLYPQSVFLNRGNHEDHVMNYRYGFVKEIQIKYKSNANKIVRFFADIFSWLPLMTIIDNSILVCHGGISA--MLNLDVIEKLDRHKFLSVLQAPVEDIKNENKEEEWMQILDLLWSDPRSKPGCSVNQYRGGGCYFGPDITNDILKKYNLSLLIRSHECKIDGYEWCHENKVVTLFSASNYYKQGSNKGAFLRIDNEHNK-QFFQYTT 1515 IE + +E Y G KL ++++ +T ++E F++++ LH + ++L +++L P++ + + + ++TICGD HGQ DL+ IF N P +NPY+ NGDFVDRGS S+E+ LF F LLYP + L RGNHE MN YGF E++ KY + ++ + F+++F WLPL I++ +LV HGG+ + + LD I K+DR++ Q P + + DLLWSDP+ + G SV++ RG C FGPD+T L+K L +IRSHE K +GYE H K +T+FSA NY Q NKGA++ + K +F Q+T Sbjct: 159 IESMTIEDDYAGPKLEDGKVTVSFMTDMMEWFKEQKKLHRKCAYQILVQVKDVLSKLPSLVEITLKETDKLTICGDTHGQYYDLLNIFKLNGLPSDANPYLFNGDFVDRGSFSLEVILTLFGFKLLYPDNFHLLRGNHETDNMNQMYGFEGEVKAKYTA---QMFQLFSEVFQWLPLAQCINSKVLVMHGGLFSEDGVTLDDIRKIDRNR-----QPP-----------DSGPMCDLLWSDPQPQNGRSVSK-RGVSCQFGPDVTESFLEKNKLDYIIRSHEVKAEGYEVTHSGKCITVFSAPNYCDQMGNKGAYIHLRGSDLKPEFHQFTA 470
BLAST of Serine/threonine-protein phosphatase with EF-hands vs. Planmine SMEST
Match: SMESG000042202.1 (SMESG000042202.1) HSP 1 Score: 1367.06 bits (3537), Expect = 0.000e+0 Identity = 658/658 (100.00%), Postives = 658/658 (100.00%), Query Frame = 1 Query: 112 MGCAQSNSPKHEYDNIYNSPKENIIENSKKTSHHVKKIYSTGDTGPISIKAAILIQNWYRRYRAKLEAKRRYTWMIYQSIEYSGEQDQLKLQSFFNDLLSLTNKGQECDSEVIEALSKTHVLKTAPTVSDEDRDLQYLTKIEQIVVEPTYKGAKLTFPLSINQVTALIESFRKEQILHARYLLELLDHTRNLLKTKPNVSQASTSISKRVTICGDLHGQLDDLVTIFYKNKFPDTSNPYIINGDFVDRGSHSVEIAAILFSFFLLYPQSVFLNRGNHEDHVMNYRYGFVKEIQIKYKSNANKIVRFFADIFSWLPLMTIIDNSILVCHGGISAMLNLDVIEKLDRHKFLSVLQAPVEDIKNENKEEEWMQILDLLWSDPRSKPGCSVNQYRGGGCYFGPDITNDILKKYNLSLLIRSHECKIDGYEWCHENKVVTLFSASNYYKQGSNKGAFLRIDNEHNKQFFQYTTHKKNQKHLTLIQSVNQIEESALRDLKGKILAFKNELAEEFIQKDVNNRGVIELQEWCTVMENVLKLPLPWRTLRPHLVKLSKEGKVEYSSIFEAQQVDNKFLMIAGTMTEELYKNKENLETIFRIMDKDNSGHISLSEFRDACKLLHRHTNRNVSEEAIEDLAKCLDINKDGQIDFNEFLEAFRIVDSSL 2085 MGCAQSNSPKHEYDNIYNSPKENIIENSKKTSHHVKKIYSTGDTGPISIKAAILIQNWYRRYRAKLEAKRRYTWMIYQSIEYSGEQDQLKLQSFFNDLLSLTNKGQECDSEVIEALSKTHVLKTAPTVSDEDRDLQYLTKIEQIVVEPTYKGAKLTFPLSINQVTALIESFRKEQILHARYLLELLDHTRNLLKTKPNVSQASTSISKRVTICGDLHGQLDDLVTIFYKNKFPDTSNPYIINGDFVDRGSHSVEIAAILFSFFLLYPQSVFLNRGNHEDHVMNYRYGFVKEIQIKYKSNANKIVRFFADIFSWLPLMTIIDNSILVCHGGISAMLNLDVIEKLDRHKFLSVLQAPVEDIKNENKEEEWMQILDLLWSDPRSKPGCSVNQYRGGGCYFGPDITNDILKKYNLSLLIRSHECKIDGYEWCHENKVVTLFSASNYYKQGSNKGAFLRIDNEHNKQFFQYTTHKKNQKHLTLIQSVNQIEESALRDLKGKILAFKNELAEEFIQKDVNNRGVIELQEWCTVMENVLKLPLPWRTLRPHLVKLSKEGKVEYSSIFEAQQVDNKFLMIAGTMTEELYKNKENLETIFRIMDKDNSGHISLSEFRDACKLLHRHTNRNVSEEAIEDLAKCLDINKDGQIDFNEFLEAFRIVDSSL Sbjct: 1 MGCAQSNSPKHEYDNIYNSPKENIIENSKKTSHHVKKIYSTGDTGPISIKAAILIQNWYRRYRAKLEAKRRYTWMIYQSIEYSGEQDQLKLQSFFNDLLSLTNKGQECDSEVIEALSKTHVLKTAPTVSDEDRDLQYLTKIEQIVVEPTYKGAKLTFPLSINQVTALIESFRKEQILHARYLLELLDHTRNLLKTKPNVSQASTSISKRVTICGDLHGQLDDLVTIFYKNKFPDTSNPYIINGDFVDRGSHSVEIAAILFSFFLLYPQSVFLNRGNHEDHVMNYRYGFVKEIQIKYKSNANKIVRFFADIFSWLPLMTIIDNSILVCHGGISAMLNLDVIEKLDRHKFLSVLQAPVEDIKNENKEEEWMQILDLLWSDPRSKPGCSVNQYRGGGCYFGPDITNDILKKYNLSLLIRSHECKIDGYEWCHENKVVTLFSASNYYKQGSNKGAFLRIDNEHNKQFFQYTTHKKNQKHLTLIQSVNQIEESALRDLKGKILAFKNELAEEFIQKDVNNRGVIELQEWCTVMENVLKLPLPWRTLRPHLVKLSKEGKVEYSSIFEAQQVDNKFLMIAGTMTEELYKNKENLETIFRIMDKDNSGHISLSEFRDACKLLHRHTNRNVSEEAIEDLAKCLDINKDGQIDFNEFLEAFRIVDSSL 658
BLAST of Serine/threonine-protein phosphatase with EF-hands vs. Planmine SMEST
Match: SMESG000042202.1 (SMESG000042202.1) HSP 1 Score: 1298.11 bits (3358), Expect = 0.000e+0 Identity = 631/658 (95.90%), Postives = 632/658 (96.05%), Query Frame = 1 Query: 112 MGCAQSNSPKHEYDNIYNSPKENIIENSKKTSHHVKKIYSTGDTGPISIKAAILIQNWYRRYRAKLEAKRRYTWMIYQSIEYSGEQDQLKLQSFFNDLLSLTNKGQECDSEVIEALSKTHVLKTAPTVSDEDRDLQYLTKIEQIVVEPTYKGAKLTFPLSINQVTALIESFRKEQILHARYLLELLDHTRNLLKTKPNVSQASTSISKRVTICGDLHGQLDDLVTIFYKNKFPDTSNPYIINGDFVDRGSHSVEIAAILFSFFLLYPQSVFLNRGNHEDHVMNYRYGFVKEIQIKYKSNANKIVRFFADIFSWLPLMTIIDNSILVCHGGISAMLNLDVIEKLDRHKFLSVLQAPVEDIKNENKEEEWMQILDLLWSDPRSKPGCSVNQYRGGGCYFGPDITNDILKKYNLSLLIRSHECKIDGYEWCHENKVVTLFSASNYYKQGSNKGAFLRIDNEHNKQFFQYTTHKKNQKHLTLIQSVNQIEESALRDLKGKILAFKNELAEEFIQKDVNNRGVIELQEWCTVMENVLKLPLPWRTLRPHLVKLSKEGKVEYSSIFEAQQVDNKFLMIAGTMTEELYKNKENLETIFRIMDKDNSGHISLSEFRDACKLLHRHTNRNVSEEAIEDLAKCLDINKDGQIDFNEFLEAFRIVDSSL 2085 MGCAQSNSPKHEYDNIYNSPK +IKAAILIQNWYRRYRAKLEAKRRYTWMIYQSIEYSGEQDQLKLQSFFNDLLSLTNKGQECDSEVIEALSKTHVLKTAPTVSDEDRDLQYLTKIEQIVVEPTYKGAKLTFPLSINQVTALIESFRKEQILHARYLLELLDHTRNLLKTKPNVSQASTSISKRVTICGDLHGQLDDLVTIFYKNKFPDTSNPYIINGDFVDRGSHSVEIAAILFSFFLLYPQSVFLNRGNHEDHVMNYRYGFVKEIQIKYKSNANKIVRFFADIFSWLPLMTIIDNSILVCHGGISAMLNLDVIEKLDRHKFLSVLQAPVEDIKNENKEEEWMQILDLLWSDPRSKPGCSVNQYRGGGCYFGPDITNDILKKYNLSLLIRSHECKIDGYEWCHENKVVTLFSASNYYKQGSNKGAFLRIDNEHNKQFFQYTTHKKNQKHLTLIQSVNQIEESALRDLKGKILAFKNELAEEFIQKDVNNRGVIELQEWCTVMENVLKLPLPWRTLRPHLVKLSKEGKVEYSSIFEAQQVDNKFLMIAGTMTEELYKNKENLETIFRIMDKDNSGHISLSEFRDACKLLHRHTNRNVSEEAIEDLAKCLDINKDGQIDFNEFLEAFRIVDSSL Sbjct: 1 MGCAQSNSPKHEYDNIYNSPK--------------------------AIKAAILIQNWYRRYRAKLEAKRRYTWMIYQSIEYSGEQDQLKLQSFFNDLLSLTNKGQECDSEVIEALSKTHVLKTAPTVSDEDRDLQYLTKIEQIVVEPTYKGAKLTFPLSINQVTALIESFRKEQILHARYLLELLDHTRNLLKTKPNVSQASTSISKRVTICGDLHGQLDDLVTIFYKNKFPDTSNPYIINGDFVDRGSHSVEIAAILFSFFLLYPQSVFLNRGNHEDHVMNYRYGFVKEIQIKYKSNANKIVRFFADIFSWLPLMTIIDNSILVCHGGISAMLNLDVIEKLDRHKFLSVLQAPVEDIKNENKEEEWMQILDLLWSDPRSKPGCSVNQYRGGGCYFGPDITNDILKKYNLSLLIRSHECKIDGYEWCHENKVVTLFSASNYYKQGSNKGAFLRIDNEHNKQFFQYTTHKKNQKHLTLIQSVNQIEESALRDLKGKILAFKNELAEEFIQKDVNNRGVIELQEWCTVMENVLKLPLPWRTLRPHLVKLSKEGKVEYSSIFEAQQVDNKFLMIAGTMTEELYKNKENLETIFRIMDKDNSGHISLSEFRDACKLLHRHTNRNVSEEAIEDLAKCLDINKDGQIDFNEFLEAFRIVDSSL 632
BLAST of Serine/threonine-protein phosphatase with EF-hands vs. Planmine SMEST
Match: SMESG000076282.1 (SMESG000076282.1) HSP 1 Score: 682.174 bits (1759), Expect = 0.000e+0 Identity = 325/612 (53.10%), Postives = 437/612 (71.41%), Query Frame = 1 Query: 250 ISIKAAILIQNWYRRYRAKLEAKRRYTWMIYQSIEYSGEQDQLKLQSFFNDLLSLTNKGQE---CDSEVIEALSKTHVLKTAPTVSDEDRDLQYLTKIEQIVVEPTYKGAKLTFPLSINQVTALIESFRKEQILHARYLLELLDHTRNLLKTKPNVSQASTSISKRVTICGDLHGQLDDLVTIFYKNKFPDTSNPYIINGDFVDRGSHSVEIAAILFSFFLLYPQSVFLNRGNHEDHVMNYRYGFVKEIQIKYKSNANKIVRFFADIFSWLPLMTIIDNSILVCHGGISAMLNLDVIEKLDRHKFLSVLQAPVEDIKNENKEEEWMQILDLLWSDPRSKPGCSVNQYRGGGCYFGPDITNDILKKYNLSLLIRSHECKIDGYEWCHENKVVTLFSASNYYKQGSNKGAFLRIDNEHNKQFFQYTTHKKNQKHLTLIQSVNQIEESALRDLKGKILAFKNELAEEFIQKDVNNRGVIELQEWCTVMENVLKLPLPWRTLRPHLVKLSKEGKVEYSSIFE-AQQVDNK-FLMIAGTMTEELYKNKENLETIFRIMDKDNSGHISLSEFRDACKLLHRHTNRNVSEEAIEDLAKCLDINKDGQIDFNEFLEAFRI 2070 I +K+ I IQ WYR Y+A+LEA+R+ +WMIYQSIEYSGEQDQLKL +FF DL++L GQ+ DS +AL+K+ +K + ++ I +E Y G + FPL++ +T+LI +F EQILH YL ELL TR +LKTKPN+S+ SI K +TICGDLHGQL DL+ IF +N++PD SNPY+ NGDF+DRG HSVEIA ILFSF +LYP VFLNRGNHED +MN RYGF+KE+Q KYK++AN I+ FADIF WLPL TII N I +CHGGIS + L+ ++ +DR K++S L P + +E + EW+Q+LD+LWSDP+ + GC N +RGGGCYFGPDIT+ L+KY LLIRSHECK GYEWCH+++V+T+FSASNYY GSNKGAF+++ + + K+ QKH+ + + ++ IEESALR+L+ KIL +++L EF+ D +N G+IE Q WC +M VL+L LPWRTLR L ++ G + YSS FE ++D+K M ++++E+YK ++ LET+FRI+D DNSG IS+ EF++ CK+L H+ N++ EA+EDLA+ +DINKDG ID NEFLEAFRI Sbjct: 30 IMMKSVIAIQKWYRGYQARLEARRKCSWMIYQSIEYSGEQDQLKLHNFFLDLMNLM--GQQNLSSDSLFTKALNKSTSIKRSSEYEND------------IPLETDYSGPIIQFPLTLTVITSLINAFNNEQILHGHYLFELLVQTRGILKTKPNISETDLSIFKHITICGDLHGQLQDLIYIFEENRYPDPSNPYVFNGDFIDRGKHSVEIAVILFSFLILYPGCVFLNRGNHEDKIMNLRYGFIKEVQTKYKAHANSIINLFADIFRWLPLATIISNKIFICHGGISNRIQLETLKNIDRSKYISALNCPSD---SELDQAEWLQVLDILWSDPKPQKGCRQNLFRGGGCYFGPDITHQFLEKYKFRLLIRSHECKPLGYEWCHKDEVLTIFSASNYYDTGSNKGAFVKLTKSLEPKIISFNAKKEFQKHILINEGIHAIEESALRELRTKILTNRSQLMSEFLACDGDNSGLIECQHWCNIMAAVLQLDLPWRTLRNQLAVVTPSGAINYSSTFELLSRMDSKQNHMNKISVSDEIYKYRDTLETVFRILDSDNSGRISIDEFKEGCKILKSHSKANMTPEAMEDLARSIDINKDGSIDLNEFLEAFRI 624
BLAST of Serine/threonine-protein phosphatase with EF-hands vs. Planmine SMEST
Match: SMESG000076282.1 (SMESG000076282.1) HSP 1 Score: 680.248 bits (1754), Expect = 0.000e+0 Identity = 324/610 (53.11%), Postives = 436/610 (71.48%), Query Frame = 1 Query: 256 IKAAILIQNWYRRYRAKLEAKRRYTWMIYQSIEYSGEQDQLKLQSFFNDLLSLTNKGQE---CDSEVIEALSKTHVLKTAPTVSDEDRDLQYLTKIEQIVVEPTYKGAKLTFPLSINQVTALIESFRKEQILHARYLLELLDHTRNLLKTKPNVSQASTSISKRVTICGDLHGQLDDLVTIFYKNKFPDTSNPYIINGDFVDRGSHSVEIAAILFSFFLLYPQSVFLNRGNHEDHVMNYRYGFVKEIQIKYKSNANKIVRFFADIFSWLPLMTIIDNSILVCHGGISAMLNLDVIEKLDRHKFLSVLQAPVEDIKNENKEEEWMQILDLLWSDPRSKPGCSVNQYRGGGCYFGPDITNDILKKYNLSLLIRSHECKIDGYEWCHENKVVTLFSASNYYKQGSNKGAFLRIDNEHNKQFFQYTTHKKNQKHLTLIQSVNQIEESALRDLKGKILAFKNELAEEFIQKDVNNRGVIELQEWCTVMENVLKLPLPWRTLRPHLVKLSKEGKVEYSSIFE-AQQVDNK-FLMIAGTMTEELYKNKENLETIFRIMDKDNSGHISLSEFRDACKLLHRHTNRNVSEEAIEDLAKCLDINKDGQIDFNEFLEAFRI 2070 +K+ I IQ WYR Y+A+LEA+R+ +WMIYQSIEYSGEQDQLKL +FF DL++L GQ+ DS +AL+K+ +K + ++ I +E Y G + FPL++ +T+LI +F EQILH YL ELL TR +LKTKPN+S+ SI K +TICGDLHGQL DL+ IF +N++PD SNPY+ NGDF+DRG HSVEIA ILFSF +LYP VFLNRGNHED +MN RYGF+KE+Q KYK++AN I+ FADIF WLPL TII N I +CHGGIS + L+ ++ +DR K++S L P + +E + EW+Q+LD+LWSDP+ + GC N +RGGGCYFGPDIT+ L+KY LLIRSHECK GYEWCH+++V+T+FSASNYY GSNKGAF+++ + + K+ QKH+ + + ++ IEESALR+L+ KIL +++L EF+ D +N G+IE Q WC +M VL+L LPWRTLR L ++ G + YSS FE ++D+K M ++++E+YK ++ LET+FRI+D DNSG IS+ EF++ CK+L H+ N++ EA+EDLA+ +DINKDG ID NEFLEAFRI Sbjct: 28 MKSVIAIQKWYRGYQARLEARRKCSWMIYQSIEYSGEQDQLKLHNFFLDLMNLM--GQQNLSSDSLFTKALNKSTSIKRSSEYEND------------IPLETDYSGPIIQFPLTLTVITSLINAFNNEQILHGHYLFELLVQTRGILKTKPNISETDLSIFKHITICGDLHGQLQDLIYIFEENRYPDPSNPYVFNGDFIDRGKHSVEIAVILFSFLILYPGCVFLNRGNHEDKIMNLRYGFIKEVQTKYKAHANSIINLFADIFRWLPLATIISNKIFICHGGISNRIQLETLKNIDRSKYISALNCPSD---SELDQAEWLQVLDILWSDPKPQKGCRQNLFRGGGCYFGPDITHQFLEKYKFRLLIRSHECKPLGYEWCHKDEVLTIFSASNYYDTGSNKGAFVKLTKSLEPKIISFNAKKEFQKHILINEGIHAIEESALRELRTKILTNRSQLMSEFLACDGDNSGLIECQHWCNIMAAVLQLDLPWRTLRNQLAVVTPSGAINYSSTFELLSRMDSKQNHMNKISVSDEIYKYRDTLETVFRILDSDNSGRISIDEFKEGCKILKSHSKANMTPEAMEDLARSIDINKDGSIDLNEFLEAFRI 620
BLAST of Serine/threonine-protein phosphatase with EF-hands vs. Planmine SMEST
Match: SMESG000003989.1 (SMESG000003989.1) HSP 1 Score: 378.252 bits (970), Expect = 1.700e-121 Identity = 235/615 (38.21%), Postives = 339/615 (55.12%), Query Frame = 1 Query: 253 SIKAAILIQNWYRRYRAKLEAKRRYTWMIYQSIEYSGEQDQLKLQSFFNDLLSLT-NKGQECDSEVIEALSKTHVLKTAPTVSDEDRDLQYLTKIEQIVVEPTYKGAKLTFPLSINQVTALIESFRK-EQILHARYLLELLDHTRNLLKTKPNVSQASTSISKRVTICGDLHGQLDDLVTIFYKNKFPDTSNPYIINGDFVDRGSHSVEIAAILFSFFLLYPQSVFLNRGNHEDHVMNYRYGFVKEIQIKYKSNANKIVRFFADIFSWLPLMTIIDNSILVCHGGISAMLNLDVIEKLDRHKFLSVLQAPVEDIKNENKEEEWMQILDLLWSDPRSKPGCSVNQYRGGGCYFGPDITNDILKKYNLSLLIRSHECKIDGYEWCHENKVVTLFSASNYYKQGSNKGAFLRIDNEHNKQFFQYTTHKKNQKHLTLIQSVNQIEESALRDLKGKILAFKNELAEEFIQKDVNN----RGVIELQEWCTVMENVLKLPLPWRTLRPHLVKLS-KEGKVEYSSIFEAQQVD--NKFLMIAGTMTEELYKNKENLETIFRIMDKDNSGHISLSEFRDACKLLHRHTNRNVSEEAIEDLAKCLDINKDGQIDFNEFLEAFRI 2070 ++KA +LIQ +YRRYRAK EAKR+ W I+Q +EYS EQ+Q+ +Q LLS+T + E +V SK + + D Q + + ++ ++ G KL +P++ V L+E ++ L R L+ELL + +L+ PNV + S +TICGD+HG DDLVTIF KN P TSNPY+ NGDFVDRGS SVE+ ++L FL P +VFLNRGNHEDH MN RYGF KE+ +++KF SVLQ +++ NE + EW Q+L+LLWSDPR GC +N YRGGGCYFGPD+T L+K + L+IRSHECK++G+++CHE+KV+TLFSASNYY+ GSN GAF ID N + QY K+Q+ + ++ EE ++R L +I +N L ++F + D++ GVI + +W T M ++ + LPWR L+ +L+ S E V Y ++ ++ NK + G + N+E +F ++D SGH++ EF + + N + +E + L K D+N DG ID EFL+ RI Sbjct: 98 TLKAVLLIQKYYRRYRAKCEAKRKMIWKIHQLVEYSNEQNQILMQK----LLSITLHNNPERHFDVKCKFSKFNDILPP--------DKQAIPWADIDALDASHNGFKLKYPITSKIVRNLVEFYKSGNNKLSNRDLIELLLRAQVVLRDLPNVYEISPV---SITICGDIHGNFDDLVTIFQKNCLPSTSNPYLFNGDFVDRGSKSVEVISVLLVCFLQNPNAVFLNRGNHEDHFMNSRYGFFKELN--------------------------------------------------NKYKFKSVLQYESDNM-NECEINEWKQVLNLLWSDPRPLNGCKMNTYRGGGCYFGPDVTLQFLEKNFMKLIIRSHECKMNGWDYCHEDKVLTLFSASNYYELGSNYGAFAIIDKSANVRITQY----KSQEGVDFRKN----EEESVRCLMSEIWRKRNSLLKKFREFDIDKSDKYSGVISIGQWVTAMSTIMNMDLPWRQLKWYLIPTSLVETDVPYLTMINNAEIQYTNKKISSLGEIDSRF---DSNVEEMFHVLDSKYSGHLTFPEFAEFIQNTTLGQNP-LQDEELTQLWKNFDLNNDGWIDKEEFLKIARI 634 The following BLAST results are available for this feature:
BLAST of Serine/threonine-protein phosphatase with EF-hands vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of Serine/threonine-protein phosphatase with EF-hands vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of Serine/threonine-protein phosphatase with EF-hands vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of Serine/threonine-protein phosphatase with EF-hands vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of Serine/threonine-protein phosphatase with EF-hands vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of Serine/threonine-protein phosphatase with EF-hands vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of Serine/threonine-protein phosphatase with EF-hands vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of Serine/threonine-protein phosphatase with EF-hands vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Serine/threonine-protein phosphatase with EF-hands vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of Serine/threonine-protein phosphatase with EF-hands vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 5
BLAST of Serine/threonine-protein phosphatase with EF-hands vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 5
BLAST of Serine/threonine-protein phosphatase with EF-hands vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of Serine/threonine-protein phosphatase with EF-hands vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of Serine/threonine-protein phosphatase with EF-hands vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30028575 ID=SMED30028575|Name=Serine/threonine-protein phosphatase with EF-hands|organism=Schmidtea mediterranea sexual|type=transcript|length=2226bpback to top protein sequence of SMED30028575-orf-1 >SMED30028575-orf-1 ID=SMED30028575-orf-1|Name=SMED30028575-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=659bp MGCAQSNSPKHEYDNIYNSPKENIIENSKKTSHHVKKIYSTGDTGPISIKback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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