Phosphodiesterase

Overview


Name	Phosphodiesterase
Smed ID	SMED30028562
Length (bp)	3232

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of Phosphodiesterase (SMED30028562) t-SNE clustered cells

Violin plots show distribution of expression levels for Phosphodiesterase (SMED30028562) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Phosphodiesterase (SMED30028562) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Phosphodiesterase (SMED30028562) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30028562

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 7

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication
nervous system	SMED30028562	h1SMcG0008300	dd_Smed_v4_3394_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
cephalic ganglia	SMED30028562	h1SMcG0008300	dd_Smed_v4_3394_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
muscle cell	SMED30028562	h1SMcG0008300	dd_Smed_v4_3394_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
parapharyngeal region	SMED30028562	h1SMcG0008300	dd_Smed_v4_3394_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
parenchyma	SMED30028562	h1SMcG0008300	dd_Smed_v4_3394_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
non-ciliated neuron	SMED30028562	h1SMcG0008300	dd_Smed_v4_3394_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
cilated neuron	SMED30028562	h1SMcG0008300	dd_Smed_v4_3394_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018

Note: Hover over icons to view figure legend

Homology

[Close]

BLAST of Phosphodiesterase vs. Ensembl Human
Match: PDE4D (phosphodiesterase 4D [Source:HGNC Symbol;Acc:HGNC:8783])

HSP 1 Score: 567.385 bits (1461), Expect = 0.000e+0
Identity = 280/544 (51.47%), Postives = 387/544 (71.14%), Query Frame = 3

Query: 1371 ATSRRGSLYIFRNADDVIITPFAQILASLRKVRANFMLITNITSNDEKKNKLDSINSPKIEENCSTNNKNITE-SHEKVAQETLNELEWCLNRLENIQTHRSVSDMASTKFKQIINRELSQFADSSKSGHQISDYICKTFLDSQLDDSIPEASSFERDIDDRKGKGKLESVRRSTKLVKASTEPVLNNSNLVTDSVLNASFVIEAPENDEDSETDVPLHGVHVANEEEVSKILDSDLKKWGMNLFSFADVTADQPLAVVSYTIFKDLNLINKFQIDSKTLVQFLIKAERSYRNTVPYHNNMHAADVTQSANVLLAGQALENVFSDLEILSVIFASIIHDMDHPGVTNQYLVNTNNELATLYNDNSVLENHHLAMAFSLLAKEECDFLATLSKRHRQSMRRMVIDMVLATDMSKHMTLLADLKTMVETKKVAGSGILTLDTYTDRIQILQNLVHCADLSNPTKPLHIYQKWIDRVMEEFYLQGDKERESELEISPMCDRQTASLEKSQVSFIDFIVHPLWETWSELVYPDTQGMLEALEENRQFY 2999
            + SR  S+    + DD+I+TPFAQ+LASLR VR NF  +TN+      +++  S  SP   +  S N   ITE +++K+A ETL EL+WCL++LE +QT  SVS+MAS KFK+++NREL+  ++ S+SG+Q+S++I  TFLD Q +  IP  +  E++    K K  +  +    KL+ +S+   L NS+                         +P  GV    E+ ++K L+ D+ KWG+++F  A+++ ++PL V+ +TIF++ +L+  F+I   TL+ +L+  E  Y   V YHNN+HAADV QS +VLL+  ALE VF+DLEIL+ IFAS IHD+DHPGV+NQ+L+NTN+ELA +YND+SVLENHHLA+ F LL +E CD    L+K+ RQS+R+MVID+VLATDMSKHM LLADLKTMVETKKV  SG+L LD Y+DRIQ+LQN+VHCADLSNPTKPL +Y++W DR+MEEF+ QGD+ERE  +EISPMCD+  AS+EKSQV FID+IVHPLWETW++LV+PD Q +L+ LE+NR++Y
Sbjct:  144 SMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNL------QDRAPSKRSPMCNQP-SINKATITEEAYQKLASETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEFISNTFLDKQHEVEIPSPTQKEKE----KKKRPMSQISGVKKLMHSSS---LTNSS-------------------------IPRFGVKTEQEDVLAKELE-DVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWY 647

[Close]

Query: 1371 ATSRRGSLYIFRNADDVIITPFAQILASLRKVRANFMLITNITSNDEKKNKLDSINSPKIEENCSTNNKNITE-SHEKVAQETLNELEWCLNRLENIQTHRSVSDMASTKFKQIINRELSQFADSSKSGHQISDYICKTFLDSQLDDSIPEASSFERDIDDRKGKGKLESVRRSTKLVKASTEPVLNNSNLVTDSVLNASFVIEAPENDEDSETDVPLHGVHVANEEEVSKILDSDLKKWGMNLFSFADVTADQPLAVVSYTIFKDLNLINKFQIDSKTLVQFLIKAERSYRNTVPYHNNMHAADVTQSANVLLAGQALENVFSDLEILSVIFASIIHDMDHPGVTNQYLVNTNNELATLYNDNSVLENHHLAMAFSLLAKEECDFLATLSKRHRQSMRRMVIDMVLATDMSKHMTLLADLKTMVETKKVAGSGILTLDTYTDRIQILQNLVHCADLSNPTKPLHIYQKWIDRVMEEFYLQGDKERESELEISPMCDRQTASLEKSQVSFIDFIVHPLWETWSELVYPDTQGMLEALEENRQFY 2999
            + SR  S+    + DD+I+TPFAQ+LASLR VR NF  +TN+      +++  S  SP   +  S N   ITE +++K+A ETL EL+WCL++LE +QT  SVS+MAS KFK+++NREL+  ++ S+SG+Q+S++I  TFLD Q +  IP  +  E++    K K  +  +    KL+ +S+   L NS+                         +P  GV    E+ ++K L+ D+ KWG+++F  A+++ ++PL V+ +TIF++ +L+  F+I   TL+ +L+  E  Y   V YHNN+HAADV QS +VLL+  ALE VF+DLEIL+ IFAS IHD+DHPGV+NQ+L+NTN+ELA +YND+SVLENHHLA+ F LL +E CD    L+K+ RQS+R+MVID+VLATDMSKHM LLADLKTMVETKKV  SG+L LD Y+DRIQ+LQN+VHCADLSNPTKPL +Y++W DR+MEEF+ QGD+ERE  +EISPMCD+  AS+EKSQV FID+IVHPLWETW++LV+PD Q +L+ LE+NR++Y
Sbjct:  141 SMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNL------QDRAPSKRSPMCNQP-SINKATITEEAYQKLASETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEFISNTFLDKQHEVEIPSPTQKEKE----KKKRPMSQISGVKKLMHSSS---LTNSS-------------------------IPRFGVKTEQEDVLAKELE-DVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWY 644

[Close]

BLAST of Phosphodiesterase vs. Ensembl Human
Match: PDE4D (phosphodiesterase 4D [Source:HGNC Symbol;Acc:HGNC:8783])

HSP 1 Score: 567 bits (1460), Expect = 0.000e+0
Identity = 280/544 (51.47%), Postives = 387/544 (71.14%), Query Frame = 3

Query: 1371 ATSRRGSLYIFRNADDVIITPFAQILASLRKVRANFMLITNITSNDEKKNKLDSINSPKIEENCSTNNKNITE-SHEKVAQETLNELEWCLNRLENIQTHRSVSDMASTKFKQIINRELSQFADSSKSGHQISDYICKTFLDSQLDDSIPEASSFERDIDDRKGKGKLESVRRSTKLVKASTEPVLNNSNLVTDSVLNASFVIEAPENDEDSETDVPLHGVHVANEEEVSKILDSDLKKWGMNLFSFADVTADQPLAVVSYTIFKDLNLINKFQIDSKTLVQFLIKAERSYRNTVPYHNNMHAADVTQSANVLLAGQALENVFSDLEILSVIFASIIHDMDHPGVTNQYLVNTNNELATLYNDNSVLENHHLAMAFSLLAKEECDFLATLSKRHRQSMRRMVIDMVLATDMSKHMTLLADLKTMVETKKVAGSGILTLDTYTDRIQILQNLVHCADLSNPTKPLHIYQKWIDRVMEEFYLQGDKERESELEISPMCDRQTASLEKSQVSFIDFIVHPLWETWSELVYPDTQGMLEALEENRQFY 2999
            + SR  S+    + DD+I+TPFAQ+LASLR VR NF  +TN+      +++  S  SP   +  S N   ITE +++K+A ETL EL+WCL++LE +QT  SVS+MAS KFK+++NREL+  ++ S+SG+Q+S++I  TFLD Q +  IP  +  E++    K K  +  +    KL+ +S+   L NS+                         +P  GV    E+ ++K L+ D+ KWG+++F  A+++ ++PL V+ +TIF++ +L+  F+I   TL+ +L+  E  Y   V YHNN+HAADV QS +VLL+  ALE VF+DLEIL+ IFAS IHD+DHPGV+NQ+L+NTN+ELA +YND+SVLENHHLA+ F LL +E CD    L+K+ RQS+R+MVID+VLATDMSKHM LLADLKTMVETKKV  SG+L LD Y+DRIQ+LQN+VHCADLSNPTKPL +Y++W DR+MEEF+ QGD+ERE  +EISPMCD+  AS+EKSQV FID+IVHPLWETW++LV+PD Q +L+ LE+NR++Y
Sbjct:   83 SMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNL------QDRAPSKRSPMCNQP-SINKATITEEAYQKLASETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEFISNTFLDKQHEVEIPSPTQKEKE----KKKRPMSQISGVKKLMHSSS---LTNSS-------------------------IPRFGVKTEQEDVLAKELE-DVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWY 586

[Close]

Query: 1371 ATSRRGSLYIFRNADDVIITPFAQILASLRKVRANFMLITNITSNDEKKNKLDSINSPKIEENCSTNNKNITE-SHEKVAQETLNELEWCLNRLENIQTHRSVSDMASTKFKQIINRELSQFADSSKSGHQISDYICKTFLDSQLDDSIPEASSFERDIDDRKGKGKLESVRRSTKLVKASTEPVLNNSNLVTDSVLNASFVIEAPENDEDSETDVPLHGVHVANEEEVSKILDSDLKKWGMNLFSFADVTADQPLAVVSYTIFKDLNLINKFQIDSKTLVQFLIKAERSYRNTVPYHNNMHAADVTQSANVLLAGQALENVFSDLEILSVIFASIIHDMDHPGVTNQYLVNTNNELATLYNDNSVLENHHLAMAFSLLAKEECDFLATLSKRHRQSMRRMVIDMVLATDMSKHMTLLADLKTMVETKKVAGSGILTLDTYTDRIQILQNLVHCADLSNPTKPLHIYQKWIDRVMEEFYLQGDKERESELEISPMCDRQTASLEKSQVSFIDFIVHPLWETWSELVYPDTQGMLEALEENRQFY 2999
            + SR  S+    + DD+I+TPFAQ+LASLR VR NF  +TN+      +++  S  SP   +  S N   ITE +++K+A ETL EL+WCL++LE +QT  SVS+MAS KFK+++NREL+  ++ S+SG+Q+S++I  TFLD Q +  IP  +  E++    K K  +  +    KL+ +S+   L NS+                         +P  GV    E+ ++K L+ D+ KWG+++F  A+++ ++PL V+ +TIF++ +L+  F+I   TL+ +L+  E  Y   V YHNN+HAADV QS +VLL+  ALE VF+DLEIL+ IFAS IHD+DHPGV+NQ+L+NTN+ELA +YND+SVLENHHLA+ F LL +E CD    L+K+ RQS+R+MVID+VLATDMSKHM LLADLKTMVETKKV  SG+L LD Y+DRIQ+LQN+VHCADLSNPTKPL +Y++W DR+MEEF+ QGD+ERE  +EISPMCD+  AS+EKSQV FID+IVHPLWETW++LV+PD Q +L+ LE+NR++Y
Sbjct:   75 SMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNL------QDRAPSKRSPMCNQP-SINKATITEEAYQKLASETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEFISNTFLDKQHEVEIPSPTQKEKE----KKKRPMSQISGVKKLMHSSS---LTNSS-------------------------IPRFGVKTEQEDVLAKELE-DVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWY 578

[Close]

BLAST of Phosphodiesterase vs. Ensembl Human
Match: PDE4D (phosphodiesterase 4D [Source:HGNC Symbol;Acc:HGNC:8783])

HSP 1 Score: 567 bits (1460), Expect = 0.000e+0
Identity = 280/542 (51.66%), Postives = 386/542 (71.22%), Query Frame = 3

Query: 1377 SRRGSLYIFRNADDVIITPFAQILASLRKVRANFMLITNITSNDEKKNKLDSINSPKIEENCSTNNKNITE-SHEKVAQETLNELEWCLNRLENIQTHRSVSDMASTKFKQIINRELSQFADSSKSGHQISDYICKTFLDSQLDDSIPEASSFERDIDDRKGKGKLESVRRSTKLVKASTEPVLNNSNLVTDSVLNASFVIEAPENDEDSETDVPLHGVHVANEEEVSKILDSDLKKWGMNLFSFADVTADQPLAVVSYTIFKDLNLINKFQIDSKTLVQFLIKAERSYRNTVPYHNNMHAADVTQSANVLLAGQALENVFSDLEILSVIFASIIHDMDHPGVTNQYLVNTNNELATLYNDNSVLENHHLAMAFSLLAKEECDFLATLSKRHRQSMRRMVIDMVLATDMSKHMTLLADLKTMVETKKVAGSGILTLDTYTDRIQILQNLVHCADLSNPTKPLHIYQKWIDRVMEEFYLQGDKERESELEISPMCDRQTASLEKSQVSFIDFIVHPLWETWSELVYPDTQGMLEALEENRQFY 2999
            SR  S+    + DD+I+TPFAQ+LASLR VR NF  +TN+      +++  S  SP   +  S N   ITE +++K+A ETL EL+WCL++LE +QT  SVS+MAS KFK+++NREL+  ++ S+SG+Q+S++I  TFLD Q +  IP  +  E++    K K  +  +    KL+ +S+   L NS+                         +P  GV    E+ ++K L+ D+ KWG+++F  A+++ ++PL V+ +TIF++ +L+  F+I   TL+ +L+  E  Y   V YHNN+HAADV QS +VLL+  ALE VF+DLEIL+ IFAS IHD+DHPGV+NQ+L+NTN+ELA +YND+SVLENHHLA+ F LL +E CD    L+K+ RQS+R+MVID+VLATDMSKHM LLADLKTMVETKKV  SG+L LD Y+DRIQ+LQN+VHCADLSNPTKPL +Y++W DR+MEEF+ QGD+ERE  +EISPMCD+  AS+EKSQV FID+IVHPLWETW++LV+PD Q +L+ LE+NR++Y
Sbjct:  207 SRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNL------QDRAPSKRSPMCNQP-SINKATITEEAYQKLASETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEFISNTFLDKQHEVEIPSPTQKEKE----KKKRPMSQISGVKKLMHSSS---LTNSS-------------------------IPRFGVKTEQEDVLAKELE-DVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWY 708

[Close]

BLAST of Phosphodiesterase vs. Ensembl Celegans
Match: pde-4 (Probable 3',5'-cyclic phosphodiesterase pde-4 [Source:UniProtKB/Swiss-Prot;Acc:Q22000])

HSP 1 Score: 525.013 bits (1351), Expect = 1.736e-175
Identity = 265/547 (48.45%), Postives = 372/547 (68.01%), Query Frame = 3

Query: 1389 SLYIFRNADDVIITPFAQILASLRKVRANFMLITNITSNDEKKNKLDSINSPKIEENCSTNNKNITESHEKVAQETLNELEWCLNRLENIQTHRSVSDMASTKFKQIINRELSQFADSSKSGHQISDYICKTFLDSQLDDSIPEASSFERDIDDRKGKGKLESVRRSTKLVKASTEPVLNNSNLVTDSVLNASFVIEAPENDEDSETDVPLHGVHVANEEEVSKILDSDLKKWGMNLFSFADVTADQPLAVVSYTIFKDLNLINKFQIDSKTLVQFLIKAERSYRNTVPYHNNMHAADVTQSANVLLAGQALENVFSDLEILSVIFASIIHDMDHPGVTNQYLVNTNNELATLYNDNSVLENHHLAMAFSLLAKEECDFLATLSKRHRQSMRRMVIDMVLATDMSKHMTLLADLKTMVETKKVAGSGILTLDTYTDRIQILQNLVHCADLSNPTKPLHIYQKWIDRVMEEFYLQGDKERESELEISPMCDRQTASLEKSQVSFIDFIVHPLWETWSELVYPDTQGMLEALEENRQFYFNKSQEKSKT 3029
            S +  R+ DD+I+TPFAQ+LASLR VR+N + ITNI ++D+ ++   S   P +      +N  + +     A +TL EL+WCL++LE IQTHRSVS+MAS+KF++++N+ELS FA+SSKSG Q+S ++  T++D + D+      S E ++   + +G   S   +  ++K +    +N  + V          + AP +D      VP +GV+ A E  V       L  WG ++F   +++ +  L VV++++ +  NL   F+I   TLV +L+  E  YRN   YHN +HAADV QS +VLL    L  VF+DLE+L+ IFA  +HD+DHPG TNQYL+N+NNELA +YND SVLE HHLA+AF LL    CDFLA LS++ R   R++VIDMVLATDMSKHM+LLADLKTMVE KKVAG+ ++ LD Y D+IQ+LQ+++H ADLSNPTKP+ +YQ+W  R+MEE++ QGDKE+E  LEISPMCDR   ++EKSQV FID+IVHPL+ETW++LVYPD Q +L+ LEENR++Y ++  E+  T
Sbjct:   20 SGFTLRHGDDLIVTPFAQLLASLRNVRSNLISITNIQNSDDSRHANRSAKRPPL------HNIELPDDVVHCAHDTLEELDWCLDQLETIQTHRSVSEMASSKFRKMLNKELSHFAESSKSGTQVSKFLITTYMDKEEDEP-----SIEIEVP-TEVQGPSTSGPMTLSILKKAQTAAMNKISGVRK--------LRAPSHD----GHVPEYGVNCAREIAVHM---QRLDDWGPDVFKIDELSKNHSLTVVTFSLLRQRNLFKTFEIHQSTLVTYLLNLEHHYRNN-HYHNFIHAADVAQSMHVLLMSPVLTEVFTDLEVLAAIFAGAVHDVDHPGFTNQYLINSNNELAIMYNDESVLEQHHLAVAFKLLQDSNCDFLANLSRKQRLQFRKIVIDMVLATDMSKHMSLLADLKTMVEAKKVAGNNVIVLDKYNDKIQVLQSMIHLADLSNPTKPIELYQQWNQRIMEEYWRQGDKEKELGLEISPMCDRGNVTIEKSQVGFIDYIVHPLYETWADLVYPDAQNILDQLEENREWYQSRIPEEPDT 538

[Close]

BLAST of Phosphodiesterase vs. Ensembl Celegans
Match: pde-4 (Probable 3',5'-cyclic phosphodiesterase pde-4 [Source:UniProtKB/Swiss-Prot;Acc:Q22000])

HSP 1 Score: 522.702 bits (1345), Expect = 9.657e-174
Identity = 263/541 (48.61%), Postives = 369/541 (68.21%), Query Frame = 3

Query: 1407 NADDVIITPFAQILASLRKVRANFMLITNITSNDEKKNKLDSINSPKIEENCSTNNKNITESHEKVAQETLNELEWCLNRLENIQTHRSVSDMASTKFKQIINRELSQFADSSKSGHQISDYICKTFLDSQLDDSIPEASSFERDIDDRKGKGKLESVRRSTKLVKASTEPVLNNSNLVTDSVLNASFVIEAPENDEDSETDVPLHGVHVANEEEVSKILDSDLKKWGMNLFSFADVTADQPLAVVSYTIFKDLNLINKFQIDSKTLVQFLIKAERSYRNTVPYHNNMHAADVTQSANVLLAGQALENVFSDLEILSVIFASIIHDMDHPGVTNQYLVNTNNELATLYNDNSVLENHHLAMAFSLLAKEECDFLATLSKRHRQSMRRMVIDMVLATDMSKHMTLLADLKTMVETKKVAGSGILTLDTYTDRIQILQNLVHCADLSNPTKPLHIYQKWIDRVMEEFYLQGDKERESELEISPMCDRQTASLEKSQVSFIDFIVHPLWETWSELVYPDTQGMLEALEENRQFYFNKSQEKSKT 3029
            + DD+I+TPFAQ+LASLR VR+N + ITNI ++D+ ++   S   P +      +N  + +     A +TL EL+WCL++LE IQTHRSVS+MAS+KF++++N+ELS FA+SSKSG Q+S ++  T++D + D+      S E ++   + +G   S   +  ++K +    +N  + V          + AP +D      VP +GV+ A E  V       L  WG ++F   +++ +  L VV++++ +  NL   F+I   TLV +L+  E  YRN   YHN +HAADV QS +VLL    L  VF+DLE+L+ IFA  +HD+DHPG TNQYL+N+NNELA +YND SVLE HHLA+AF LL    CDFLA LS++ R   R++VIDMVLATDMSKHM+LLADLKTMVE KKVAG+ ++ LD Y D+IQ+LQ+++H ADLSNPTKP+ +YQ+W  R+MEE++ QGDKE+E  LEISPMCDR   ++EKSQV FID+IVHPL+ETW++LVYPD Q +L+ LEENR++Y ++  E+  T
Sbjct:   76 HGDDLIVTPFAQLLASLRNVRSNLISITNIQNSDDSRHANRSAKRPPL------HNIELPDDVVHCAHDTLEELDWCLDQLETIQTHRSVSEMASSKFRKMLNKELSHFAESSKSGTQVSKFLITTYMDKEEDEP-----SIEIEVP-TEVQGPSTSGPMTLSILKKAQTAAMNKISGVRK--------LRAPSHD----GHVPEYGVNCAREIAVHM---QRLDDWGPDVFKIDELSKNHSLTVVTFSLLRQRNLFKTFEIHQSTLVTYLLNLEHHYRNN-HYHNFIHAADVAQSMHVLLMSPVLTEVFTDLEVLAAIFAGAVHDVDHPGFTNQYLINSNNELAIMYNDESVLEQHHLAVAFKLLQDSNCDFLANLSRKQRLQFRKIVIDMVLATDMSKHMSLLADLKTMVEAKKVAGNNVIVLDKYNDKIQVLQSMIHLADLSNPTKPIELYQQWNQRIMEEYWRQGDKEKELGLEISPMCDRGNVTIEKSQVGFIDYIVHPLYETWADLVYPDAQNILDQLEENREWYQSRIPEEPDT 588

[Close]

BLAST of Phosphodiesterase vs. Ensembl Celegans
Match: pde-4 (Probable 3',5'-cyclic phosphodiesterase pde-4 [Source:UniProtKB/Swiss-Prot;Acc:Q22000])

HSP 1 Score: 522.316 bits (1344), Expect = 1.668e-173
Identity = 263/541 (48.61%), Postives = 369/541 (68.21%), Query Frame = 3

Query: 1407 NADDVIITPFAQILASLRKVRANFMLITNITSNDEKKNKLDSINSPKIEENCSTNNKNITESHEKVAQETLNELEWCLNRLENIQTHRSVSDMASTKFKQIINRELSQFADSSKSGHQISDYICKTFLDSQLDDSIPEASSFERDIDDRKGKGKLESVRRSTKLVKASTEPVLNNSNLVTDSVLNASFVIEAPENDEDSETDVPLHGVHVANEEEVSKILDSDLKKWGMNLFSFADVTADQPLAVVSYTIFKDLNLINKFQIDSKTLVQFLIKAERSYRNTVPYHNNMHAADVTQSANVLLAGQALENVFSDLEILSVIFASIIHDMDHPGVTNQYLVNTNNELATLYNDNSVLENHHLAMAFSLLAKEECDFLATLSKRHRQSMRRMVIDMVLATDMSKHMTLLADLKTMVETKKVAGSGILTLDTYTDRIQILQNLVHCADLSNPTKPLHIYQKWIDRVMEEFYLQGDKERESELEISPMCDRQTASLEKSQVSFIDFIVHPLWETWSELVYPDTQGMLEALEENRQFYFNKSQEKSKT 3029
            + DD+I+TPFAQ+LASLR VR+N + ITNI ++D+ ++   S   P +      +N  + +     A +TL EL+WCL++LE IQTHRSVS+MAS+KF++++N+ELS FA+SSKSG Q+S ++  T++D + D+      S E ++   + +G   S   +  ++K +    +N  + V          + AP +D      VP +GV+ A E  V       L  WG ++F   +++ +  L VV++++ +  NL   F+I   TLV +L+  E  YRN   YHN +HAADV QS +VLL    L  VF+DLE+L+ IFA  +HD+DHPG TNQYL+N+NNELA +YND SVLE HHLA+AF LL    CDFLA LS++ R   R++VIDMVLATDMSKHM+LLADLKTMVE KKVAG+ ++ LD Y D+IQ+LQ+++H ADLSNPTKP+ +YQ+W  R+MEE++ QGDKE+E  LEISPMCDR   ++EKSQV FID+IVHPL+ETW++LVYPD Q +L+ LEENR++Y ++  E+  T
Sbjct:   89 HGDDLIVTPFAQLLASLRNVRSNLISITNIQNSDDSRHANRSAKRPPL------HNIELPDDVVHCAHDTLEELDWCLDQLETIQTHRSVSEMASSKFRKMLNKELSHFAESSKSGTQVSKFLITTYMDKEEDEP-----SIEIEVPT-EVQGPSTSGPMTLSILKKAQTAAMNKISGVRK--------LRAPSHD----GHVPEYGVNCAREIAVHM---QRLDDWGPDVFKIDELSKNHSLTVVTFSLLRQRNLFKTFEIHQSTLVTYLLNLEHHYRNN-HYHNFIHAADVAQSMHVLLMSPVLTEVFTDLEVLAAIFAGAVHDVDHPGFTNQYLINSNNELAIMYNDESVLEQHHLAVAFKLLQDSNCDFLANLSRKQRLQFRKIVIDMVLATDMSKHMSLLADLKTMVEAKKVAGNNVIVLDKYNDKIQVLQSMIHLADLSNPTKPIELYQQWNQRIMEEYWRQGDKEKELGLEISPMCDRGNVTIEKSQVGFIDYIVHPLYETWADLVYPDAQNILDQLEENREWYQSRIPEEPDT 601

[Close]

BLAST of Phosphodiesterase vs. Ensembl Celegans
Match: pde-4 (Probable 3',5'-cyclic phosphodiesterase pde-4 [Source:UniProtKB/Swiss-Prot;Acc:Q22000])

HSP 1 Score: 521.931 bits (1343), Expect = 3.161e-173
Identity = 263/541 (48.61%), Postives = 369/541 (68.21%), Query Frame = 3

Query: 1407 NADDVIITPFAQILASLRKVRANFMLITNITSNDEKKNKLDSINSPKIEENCSTNNKNITESHEKVAQETLNELEWCLNRLENIQTHRSVSDMASTKFKQIINRELSQFADSSKSGHQISDYICKTFLDSQLDDSIPEASSFERDIDDRKGKGKLESVRRSTKLVKASTEPVLNNSNLVTDSVLNASFVIEAPENDEDSETDVPLHGVHVANEEEVSKILDSDLKKWGMNLFSFADVTADQPLAVVSYTIFKDLNLINKFQIDSKTLVQFLIKAERSYRNTVPYHNNMHAADVTQSANVLLAGQALENVFSDLEILSVIFASIIHDMDHPGVTNQYLVNTNNELATLYNDNSVLENHHLAMAFSLLAKEECDFLATLSKRHRQSMRRMVIDMVLATDMSKHMTLLADLKTMVETKKVAGSGILTLDTYTDRIQILQNLVHCADLSNPTKPLHIYQKWIDRVMEEFYLQGDKERESELEISPMCDRQTASLEKSQVSFIDFIVHPLWETWSELVYPDTQGMLEALEENRQFYFNKSQEKSKT 3029
            + DD+I+TPFAQ+LASLR VR+N + ITNI ++D+ ++   S   P +      +N  + +     A +TL EL+WCL++LE IQTHRSVS+MAS+KF++++N+ELS FA+SSKSG Q+S ++  T++D + D+      S E ++   + +G   S   +  ++K +    +N  + V          + AP +D      VP +GV+ A E  V       L  WG ++F   +++ +  L VV++++ +  NL   F+I   TLV +L+  E  YRN   YHN +HAADV QS +VLL    L  VF+DLE+L+ IFA  +HD+DHPG TNQYL+N+NNELA +YND SVLE HHLA+AF LL    CDFLA LS++ R   R++VIDMVLATDMSKHM+LLADLKTMVE KKVAG+ ++ LD Y D+IQ+LQ+++H ADLSNPTKP+ +YQ+W  R+MEE++ QGDKE+E  LEISPMCDR   ++EKSQV FID+IVHPL+ETW++LVYPD Q +L+ LEENR++Y ++  E+  T
Sbjct:  101 HGDDLIVTPFAQLLASLRNVRSNLISITNIQNSDDSRHANRSAKRPPL------HNIELPDDVVHCAHDTLEELDWCLDQLETIQTHRSVSEMASSKFRKMLNKELSHFAESSKSGTQVSKFLITTYMDKEEDEP-----SIEIEVPT-EVQGPSTSGPMTLSILKKAQTAAMNKISGVRK--------LRAPSHD----GHVPEYGVNCAREIAVHM---QRLDDWGPDVFKIDELSKNHSLTVVTFSLLRQRNLFKTFEIHQSTLVTYLLNLEHHYRNN-HYHNFIHAADVAQSMHVLLMSPVLTEVFTDLEVLAAIFAGAVHDVDHPGFTNQYLINSNNELAIMYNDESVLEQHHLAVAFKLLQDSNCDFLANLSRKQRLQFRKIVIDMVLATDMSKHMSLLADLKTMVEAKKVAGNNVIVLDKYNDKIQVLQSMIHLADLSNPTKPIELYQQWNQRIMEEYWRQGDKEKELGLEISPMCDRGNVTIEKSQVGFIDYIVHPLYETWADLVYPDAQNILDQLEENREWYQSRIPEEPDT 613

[Close]

BLAST of Phosphodiesterase vs. Ensembl Celegans
Match: pde-4 (Probable 3',5'-cyclic phosphodiesterase pde-4 [Source:UniProtKB/Swiss-Prot;Acc:Q22000])

HSP 1 Score: 521.931 bits (1343), Expect = 3.755e-173
Identity = 263/541 (48.61%), Postives = 369/541 (68.21%), Query Frame = 3

Query: 1407 NADDVIITPFAQILASLRKVRANFMLITNITSNDEKKNKLDSINSPKIEENCSTNNKNITESHEKVAQETLNELEWCLNRLENIQTHRSVSDMASTKFKQIINRELSQFADSSKSGHQISDYICKTFLDSQLDDSIPEASSFERDIDDRKGKGKLESVRRSTKLVKASTEPVLNNSNLVTDSVLNASFVIEAPENDEDSETDVPLHGVHVANEEEVSKILDSDLKKWGMNLFSFADVTADQPLAVVSYTIFKDLNLINKFQIDSKTLVQFLIKAERSYRNTVPYHNNMHAADVTQSANVLLAGQALENVFSDLEILSVIFASIIHDMDHPGVTNQYLVNTNNELATLYNDNSVLENHHLAMAFSLLAKEECDFLATLSKRHRQSMRRMVIDMVLATDMSKHMTLLADLKTMVETKKVAGSGILTLDTYTDRIQILQNLVHCADLSNPTKPLHIYQKWIDRVMEEFYLQGDKERESELEISPMCDRQTASLEKSQVSFIDFIVHPLWETWSELVYPDTQGMLEALEENRQFYFNKSQEKSKT 3029
            + DD+I+TPFAQ+LASLR VR+N + ITNI ++D+ ++   S   P +      +N  + +     A +TL EL+WCL++LE IQTHRSVS+MAS+KF++++N+ELS FA+SSKSG Q+S ++  T++D + D+      S E ++   + +G   S   +  ++K +    +N  + V          + AP +D      VP +GV+ A E  V       L  WG ++F   +++ +  L VV++++ +  NL   F+I   TLV +L+  E  YRN   YHN +HAADV QS +VLL    L  VF+DLE+L+ IFA  +HD+DHPG TNQYL+N+NNELA +YND SVLE HHLA+AF LL    CDFLA LS++ R   R++VIDMVLATDMSKHM+LLADLKTMVE KKVAG+ ++ LD Y D+IQ+LQ+++H ADLSNPTKP+ +YQ+W  R+MEE++ QGDKE+E  LEISPMCDR   ++EKSQV FID+IVHPL+ETW++LVYPD Q +L+ LEENR++Y ++  E+  T
Sbjct:  103 HGDDLIVTPFAQLLASLRNVRSNLISITNIQNSDDSRHANRSAKRPPL------HNIELPDDVVHCAHDTLEELDWCLDQLETIQTHRSVSEMASSKFRKMLNKELSHFAESSKSGTQVSKFLITTYMDKEEDEP-----SIEIEVPT-EVQGPSTSGPMTLSILKKAQTAAMNKISGVRK--------LRAPSHD----GHVPEYGVNCAREIAVHM---QRLDDWGPDVFKIDELSKNHSLTVVTFSLLRQRNLFKTFEIHQSTLVTYLLNLEHHYRNN-HYHNFIHAADVAQSMHVLLMSPVLTEVFTDLEVLAAIFAGAVHDVDHPGFTNQYLINSNNELAIMYNDESVLEQHHLAVAFKLLQDSNCDFLANLSRKQRLQFRKIVIDMVLATDMSKHMSLLADLKTMVEAKKVAGNNVIVLDKYNDKIQVLQSMIHLADLSNPTKPIELYQQWNQRIMEEYWRQGDKEKELGLEISPMCDRGNVTIEKSQVGFIDYIVHPLYETWADLVYPDAQNILDQLEENREWYQSRIPEEPDT 615

[Close]

BLAST of Phosphodiesterase vs. Ensembl Fly
Match: dnc (gene:FBgn0000479 transcript:FBtr0070512)

HSP 1 Score: 562.377 bits (1448), Expect = 0.000e+0
Identity = 273/556 (49.10%), Postives = 382/556 (68.71%), Query Frame = 3

Query: 1338 RQNSRFRKPFVATSRRGSLYIFRNADDVIITPFAQILASLRKVRANFMLITNITSNDEKKNKLDSINSPKIEENCSTNNKNITESHEKVAQETLNELEWCLNRLENIQTHRSVSDMASTKFKQIINRELSQFADSSKSGHQISDYICKTFLDSQLDDSIPEASSFERDIDDRKGKGKLESVRRSTKLVKASTEPVLNNSNLVTDSVLNASFVIEAPENDEDSETD--VPLHGVHVANEEEVSKILDSDLKKWGMNLFSFADVTADQPLAVVSYTIFKDLNLINKFQIDSKTLVQFLIKAERSYRNTVPYHNNMHAADVTQSANVLLAGQALENVFSDLEILSVIFASIIHDMDHPGVTNQYLVNTNNELATLYNDNSVLENHHLAMAFSLLAKEECDFLATLSKRHRQSMRRMVIDMVLATDMSKHMTLLADLKTMVETKKVAGSGILTLDTYTDRIQILQNLVHCADLSNPTKPLHIYQKWIDRVMEEFYLQGDKERESELEISPMCDRQTASLEKSQVSFIDFIVHPLWETWSELVYPDTQGMLEALEENRQFY 2999
            R +S F     + SR  S+    + +D+I+TPFAQILASLR VR N + +TN+ ++++ +    S ++ +             E++ ++A +T+ EL+WCL++LE IQTHRSVSDMAS KFK+++N+ELS F++SS+SG+QIS+YIC TFLD Q +  +P   S   + +         + ++S      S  P     + ++         ++ P +  +S T   +P  GV    E E+  +L  +L  WG+ +FS  + + ++PL  V+YTIF+   L+    I  KT + F+   E  Y    P+HN++HAADVTQS NVLL   ALE VF+ LE+   +FA+ IHD+DHPG+TNQ+LVN+++ELA +YND SVLENHHLA+AF LL  + CD    + K+ RQ++R+MVID+VL+TDMSKHM+LLADLKTMVETKKVAGSG+L LD YTDRIQ+L+NLVHCADLSNPTKPL +Y++W+  +MEEF+LQGDKERES ++ISPMCDR  A++EKSQV FID+IVHPLWETW++LV+PD Q +L+ LEENR +Y
Sbjct:  422 RSDSDFEMSPKSMSRNSSIASESHGEDLIVTPFAQILASLRSVRNNLLSLTNVPASNKSRRPNQSSSASRSGNPPGAPLSQGEEAYTRLATDTIEELDWCLDQLETIQTHRSVSDMASLKFKRMLNKELSHFSESSRSGNQISEYICSTFLDKQQEFDLP---SLRVEDNPELVAANAAAGQQSAGQYARSRSPRGPPMSQISG--------VKRPLSHTNSFTGERLPTFGVETPRENELGTLL-GELDTWGIQIFSIGEFSVNRPLTCVAYTIFQSRELLTSLMIPPKTFLNFMSTLEDHYVKDNPFHNSLHAADVTQSTNVLLNTPALEGVFTPLEVGGALFAACIHDVDHPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQNQGCDIFCNMQKKQRQTLRKMVIDIVLSTDMSKHMSLLADLKTMVETKKVAGSGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFLQGDKERESGMDISPMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYY 965

[Close]

BLAST of Phosphodiesterase vs. Ensembl Fly
Match: dnc (gene:FBgn0000479 transcript:FBtr0070515)

HSP 1 Score: 560.066 bits (1442), Expect = 0.000e+0
Identity = 276/569 (48.51%), Postives = 391/569 (68.72%), Query Frame = 3

Query: 1302 ENMDYNSSFSVKRQNSRFRKPFVATSRRGSLYIFRN-ADDVIITPFAQILASLRKVRANFMLITNITSNDEKKNKLDSINSPKIEENCSTNNKNITESHEKVAQETLNELEWCLNRLENIQTHRSVSDMASTKFKQIINRELSQFADSSKSGHQISDYICKTFLDSQLDDSIPEASSFERDIDDRKGKGKLESVRRSTKLVKASTEPVLNNSNLVTDSVLNASFVIEAPENDEDSETD--VPLHGVHVANEEEVSKILDSDLKKWGMNLFSFADVTADQPLAVVSYTIFKDLNLINKFQIDSKTLVQFLIKAERSYRNTVPYHNNMHAADVTQSANVLLAGQALENVFSDLEILSVIFASIIHDMDHPGVTNQYLVNTNNELATLYNDNSVLENHHLAMAFSLLAKEECDFLATLSKRHRQSMRRMVIDMVLATDMSKHMTLLADLKTMVETKKVAGSGILTLDTYTDRIQILQNLVHCADLSNPTKPLHIYQKWIDRVMEEFYLQGDKERESELEISPMCDRQTASLEKSQVSFIDFIVHPLWETWSELVYPDTQGMLEALEENRQFY 2999
            ++M  NSS +    + RF++      +  S+ + R+  +D+I+TPFAQILASLR VR N + +TN+ +++++ N+  S +          +     E++ ++A +T+ EL+WCL++LE IQTHRSVSDMAS KFK+++N+ELS F++SS+SG+QIS+YIC TFLD Q +  +P   S   + +         + ++S      S  P     + ++         ++ P +  +S T   +P  GV    E E+  +L  +L  WG+ +FS  + + ++PL  V+YTIF+   L+    I  KT + F+   E  Y    P+HN++HAADVTQS NVLL   ALE VF+ LE+   +FA+ IHD+DHPG+TNQ+LVN+++ELA +YND SVLENHHLA+AF LL  + CD    + K+ RQ++R+MVID+VL+TDMSKHM+LLADLKTMVETKKVAGSG+L LD YTDRIQ+L+NLVHCADLSNPTKPL +Y++W+  +MEEF+LQGDKERES ++ISPMCDR  A++EKSQV FID+IVHPLWETW++LV+PD Q +L+ LEENR +Y
Sbjct:  432 KSMSRNSSIA----SERFKE------QEASILVDRSHGEDLIVTPFAQILASLRSVRNNLLSLTNVPASNKRPNQSSSASRSGNPPGAPLSQGE--EAYTRLATDTIEELDWCLDQLETIQTHRSVSDMASLKFKRMLNKELSHFSESSRSGNQISEYICSTFLDKQQEFDLP---SLRVEDNPELVAANAAAGQQSAGQYARSRSPRGPPMSQISG--------VKRPLSHTNSFTGERLPTFGVETPRENELGTLL-GELDTWGIQIFSIGEFSVNRPLTCVAYTIFQSRELLTSLMIPPKTFLNFMSTLEDHYVKDNPFHNSLHAADVTQSTNVLLNTPALEGVFTPLEVGGALFAACIHDVDHPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQNQGCDIFCNMQKKQRQTLRKMVIDIVLSTDMSKHMSLLADLKTMVETKKVAGSGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFLQGDKERESGMDISPMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYY 976

[Close]

BLAST of Phosphodiesterase vs. Ensembl Fly
Match: dnc (gene:FBgn0000479 transcript:FBtr0070520)

HSP 1 Score: 559.681 bits (1441), Expect = 0.000e+0
Identity = 272/555 (49.01%), Postives = 377/555 (67.93%), Query Frame = 3

Query: 1338 RQNSRFRKPFVATSRRGSLYIFRNADDVIITPFAQILASLRKVRANFMLITNITSNDEKKNKLDSINSPKIEENCSTNNKNITESHEKVAQETLNELEWCLNRLENIQTHRSVSDMASTKFKQIINRELSQFADSSKSGHQISDYICKTFLDSQLDDSIPEASSFER-DIDDRKGKGKLESVRRSTKLVKASTEPVLNNSNLVTDSVLNASFVIEAPENDEDSETDVPLHGVHVANEEEVSKILDSDLKKWGMNLFSFADVTADQPLAVVSYTIFKDLNLINKFQIDSKTLVQFLIKAERSYRNTVPYHNNMHAADVTQSANVLLAGQALENVFSDLEILSVIFASIIHDMDHPGVTNQYLVNTNNELATLYNDNSVLENHHLAMAFSLLAKEECDFLATLSKRHRQSMRRMVIDMVLATDMSKHMTLLADLKTMVETKKVAGSGILTLDTYTDRIQILQNLVHCADLSNPTKPLHIYQKWIDRVMEEFYLQGDKERESELEISPMCDRQTASLEKSQVSFIDFIVHPLWETWSELVYPDTQGMLEALEENRQFY 2999
            R +S F     + SR  S+    + +D+I+TPFAQILASLR VR N + +TN+ ++++ +    S ++ +             E++ ++A +T+ EL+WCL++LE IQTHRSVSDMAS KFK+++N+ELS F++SS+SG+QIS+YIC TFLD Q +  +P     +  ++         +S  +  +       P+   S +        SF  E           +P  GV    E E+  +L  +L  WG+ +FS  + + ++PL  V+YTIF+   L+    I  KT + F+   E  Y    P+HN++HAADVTQS NVLL   ALE VF+ LE+   +FA+ IHD+DHPG+TNQ+LVN+++ELA +YND SVLENHHLA+AF LL  + CD    + K+ RQ++R+MVID+VL+TDMSKHM+LLADLKTMVETKKVAGSG+L LD YTDRIQ+L+NLVHCADLSNPTKPL +Y++W+  +MEEF+LQGDKERES ++ISPMCDR  A++EKSQV FID+IVHPLWETW++LV+PD Q +L+ LEENR +Y
Sbjct:  179 RSDSDFEMSPKSMSRNSSIASESHGEDLIVTPFAQILASLRSVRNNLLSLTNVPASNKSRRPNQSSSASRSGNPPGAPLSQGEEAYTRLATDTIEELDWCLDQLETIQTHRSVSDMASLKFKRMLNKELSHFSESSRSGNQISEYICSTFLDKQQEFDLPSLRVEDNPELVAANAAAGQQSAGQYARSRSPRGPPMSQISGVKRPLSHTNSFTGER----------LPTFGVETPRENELGTLL-GELDTWGIQIFSIGEFSVNRPLTCVAYTIFQSRELLTSLMIPPKTFLNFMSTLEDHYVKDNPFHNSLHAADVTQSTNVLLNTPALEGVFTPLEVGGALFAACIHDVDHPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQNQGCDIFCNMQKKQRQTLRKMVIDIVLSTDMSKHMSLLADLKTMVETKKVAGSGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFLQGDKERESGMDISPMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYY 722

[Close]

BLAST of Phosphodiesterase vs. Ensembl Fly
Match: dnc (gene:FBgn0000479 transcript:FBtr0070519)

HSP 1 Score: 558.91 bits (1439), Expect = 0.000e+0
Identity = 273/556 (49.10%), Postives = 382/556 (68.71%), Query Frame = 3

Query: 1338 RQNSRFRKPFVATSRRGSLYIFRNADDVIITPFAQILASLRKVRANFMLITNITSNDEKKNKLDSINSPKIEENCSTNNKNITESHEKVAQETLNELEWCLNRLENIQTHRSVSDMASTKFKQIINRELSQFADSSKSGHQISDYICKTFLDSQLDDSIPEASSFERDIDDRKGKGKLESVRRSTKLVKASTEPVLNNSNLVTDSVLNASFVIEAPENDEDSETD--VPLHGVHVANEEEVSKILDSDLKKWGMNLFSFADVTADQPLAVVSYTIFKDLNLINKFQIDSKTLVQFLIKAERSYRNTVPYHNNMHAADVTQSANVLLAGQALENVFSDLEILSVIFASIIHDMDHPGVTNQYLVNTNNELATLYNDNSVLENHHLAMAFSLLAKEECDFLATLSKRHRQSMRRMVIDMVLATDMSKHMTLLADLKTMVETKKVAGSGILTLDTYTDRIQILQNLVHCADLSNPTKPLHIYQKWIDRVMEEFYLQGDKERESELEISPMCDRQTASLEKSQVSFIDFIVHPLWETWSELVYPDTQGMLEALEENRQFY 2999
            R +S F     + SR  S+    + +D+I+TPFAQILASLR VR N + +TN+ ++++ +    S ++ +             E++ ++A +T+ EL+WCL++LE IQTHRSVSDMAS KFK+++N+ELS F++SS+SG+QIS+YIC TFLD Q +  +P   S   + +         + ++S      S  P     + ++         ++ P +  +S T   +P  GV    E E+  +L  +L  WG+ +FS  + + ++PL  V+YTIF+   L+    I  KT + F+   E  Y    P+HN++HAADVTQS NVLL   ALE VF+ LE+   +FA+ IHD+DHPG+TNQ+LVN+++ELA +YND SVLENHHLA+AF LL  + CD    + K+ RQ++R+MVID+VL+TDMSKHM+LLADLKTMVETKKVAGSG+L LD YTDRIQ+L+NLVHCADLSNPTKPL +Y++W+  +MEEF+LQGDKERES ++ISPMCDR  A++EKSQV FID+IVHPLWETW++LV+PD Q +L+ LEENR +Y
Sbjct:  348 RSDSDFEMSPKSMSRNSSIASESHGEDLIVTPFAQILASLRSVRNNLLSLTNVPASNKSRRPNQSSSASRSGNPPGAPLSQGEEAYTRLATDTIEELDWCLDQLETIQTHRSVSDMASLKFKRMLNKELSHFSESSRSGNQISEYICSTFLDKQQEFDLP---SLRVEDNPELVAANAAAGQQSAGQYARSRSPRGPPMSQISG--------VKRPLSHTNSFTGERLPTFGVETPRENELGTLL-GELDTWGIQIFSIGEFSVNRPLTCVAYTIFQSRELLTSLMIPPKTFLNFMSTLEDHYVKDNPFHNSLHAADVTQSTNVLLNTPALEGVFTPLEVGGALFAACIHDVDHPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQNQGCDIFCNMQKKQRQTLRKMVIDIVLSTDMSKHMSLLADLKTMVETKKVAGSGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFLQGDKERESGMDISPMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYY 891

[Close]

BLAST of Phosphodiesterase vs. Ensembl Fly
Match: dnc (gene:FBgn0000479 transcript:FBtr0070513)

HSP 1 Score: 558.525 bits (1438), Expect = 0.000e+0
Identity = 275/569 (48.33%), Postives = 390/569 (68.54%), Query Frame = 3

Query: 1302 ENMDYNSSFSVKRQNSRFRKPFVATSRRGSLYIFRN-ADDVIITPFAQILASLRKVRANFMLITNITSNDEKKNKLDSINSPKIEENCSTNNKNITESHEKVAQETLNELEWCLNRLENIQTHRSVSDMASTKFKQIINRELSQFADSSKSGHQISDYICKTFLDSQLDDSIPEASSFERDIDDRKGKGKLESVRRSTKLVKASTEPVLNNSNLVTDSVLNASFVIEAPENDEDSETD--VPLHGVHVANEEEVSKILDSDLKKWGMNLFSFADVTADQPLAVVSYTIFKDLNLINKFQIDSKTLVQFLIKAERSYRNTVPYHNNMHAADVTQSANVLLAGQALENVFSDLEILSVIFASIIHDMDHPGVTNQYLVNTNNELATLYNDNSVLENHHLAMAFSLLAKEECDFLATLSKRHRQSMRRMVIDMVLATDMSKHMTLLADLKTMVETKKVAGSGILTLDTYTDRIQILQNLVHCADLSNPTKPLHIYQKWIDRVMEEFYLQGDKERESELEISPMCDRQTASLEKSQVSFIDFIVHPLWETWSELVYPDTQGMLEALEENRQFY 2999
            ++M  NSS +    + RF++      +  S+ + R+  +D+I+TPFAQILASLR VR N + +TN+ ++++ +    S ++ +             E++ ++A +T+ EL+WCL++LE IQTHRSVSDMAS KFK+++N+ELS F++SS+SG+QIS+YIC TFLD Q +  +P   S   + +         + ++S      S  P     + ++         ++ P +  +S T   +P  GV    E E+  +L  +L  WG+ +FS  + + ++PL  V+YTIF+   L+    I  KT + F+   E  Y    P+HN++HAADVTQS NVLL   ALE VF+ LE+   +FA+ IHD+DHPG+TNQ+LVN+++ELA +YND SVLENHHLA+AF LL  + CD    + K+ RQ++R+MVID+VL+TDMSKHM+LLADLKTMVETKKVAGSG+L LD YTDRIQ+L+NLVHCADLSNPTKPL +Y++W+  +MEEF+LQGDKERES ++ISPMCDR  A++EKSQV FID+IVHPLWETW++LV+PD Q +L+ LEENR +Y
Sbjct:  432 KSMSRNSSIA----SERFKE------QEASILVDRSHGEDLIVTPFAQILASLRSVRNNLLSLTNVPASNKSRRPNQSSSASRSGNPPGAPLSQGEEAYTRLATDTIEELDWCLDQLETIQTHRSVSDMASLKFKRMLNKELSHFSESSRSGNQISEYICSTFLDKQQEFDLP---SLRVEDNPELVAANAAAGQQSAGQYARSRSPRGPPMSQISG--------VKRPLSHTNSFTGERLPTFGVETPRENELGTLL-GELDTWGIQIFSIGEFSVNRPLTCVAYTIFQSRELLTSLMIPPKTFLNFMSTLEDHYVKDNPFHNSLHAADVTQSTNVLLNTPALEGVFTPLEVGGALFAACIHDVDHPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQNQGCDIFCNMQKKQRQTLRKMVIDIVLSTDMSKHMSLLADLKTMVETKKVAGSGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFLQGDKERESGMDISPMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYY 978

[Close]

BLAST of Phosphodiesterase vs. Ensembl Zebrafish
Match: pde4d (phosphodiesterase 4D, cAMP-specific [Source:ZFIN;Acc:ZDB-GENE-081105-16])

HSP 1 Score: 575.089 bits (1481), Expect = 0.000e+0
Identity = 281/543 (51.75%), Postives = 380/543 (69.98%), Query Frame = 3

Query: 1371 ATSRRGSLYIFRNADDVIITPFAQILASLRKVRANFMLITNITSNDEKKNKLDSINSPKIEENCSTNNKNITESHEKVAQETLNELEWCLNRLENIQTHRSVSDMASTKFKQIINRELSQFADSSKSGHQISDYICKTFLDSQLDDSIPEASSFERDIDDRKGKGKLESVRRSTKLVKASTEPVLNNSNLVTDSVLNASFVIEAPENDEDSETDVPLHGVHVANEEEVSKILDSDLKKWGMNLFSFADVTADQPLAVVSYTIFKDLNLINKFQIDSKTLVQFLIKAERSYRNTVPYHNNMHAADVTQSANVLLAGQALENVFSDLEILSVIFASIIHDMDHPGVTNQYLVNTNNELATLYNDNSVLENHHLAMAFSLLAKEECDFLATLSKRHRQSMRRMVIDMVLATDMSKHMTLLADLKTMVETKKVAGSGILTLDTYTDRIQILQNLVHCADLSNPTKPLHIYQKWIDRVMEEFYLQGDKERESELEISPMCDRQTASLEKSQVSFIDFIVHPLWETWSELVYPDTQGMLEALEENRQFY 2999
            + SR  S+    + DD+I+TPFAQ+LASLR VR NF  +TN+        +    N P I +   T      E+++K+A ETL EL+WCL++LE +QT  SVS+MAS KFK+++NREL+  ++ S+SG+Q+S+YI  TFLD Q +  +P   S +   D  K K  +  +    KL  +S+   L NSN                         +P  GV    E+E++K L+ D+ KWG+N+F  ++ + ++PL V+ YTIF++ +L+  F+I   T + +L+  E  Y   V YHNN+HAADVTQS +VLL+  ALE VF+DLEIL+ IFAS IHD+DHPGV+NQ+L+NTN+ELA +YND+SVLENHHLA+ F LL +E CD    L+K+ RQS+R+MVID+VLATDMSKHM LLADLKTMVETKKV  SG+L LD Y+DRIQ+LQN+VHCADLSNPTKPL +Y++W DR+MEEF+ QGD+ERE  +EISPMCD+  AS+EKSQV FID+IVHPLWETW++LV+PD Q +L+ LE+NR++Y
Sbjct:   73 SMSRNSSIASDIHGDDMIVTPFAQVLASLRTVRNNFAALTNVQQERSNNKRSPMCNPPPITKTSYTE-----EAYQKLATETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISSTFLDKQNEVEMPSPQSQK---DKEKKKRPMSQISGVKKLTHSSS---LTNSN-------------------------IPRFGVKTETEDELAKELE-DVNKWGLNVFKVSEFSGNRPLTVMMYTIFQERDLLKTFKIPLDTFITYLMTLEDHYHADVAYHNNIHAADVTQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFSQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWY 578

[Close]

BLAST of Phosphodiesterase vs. Ensembl Zebrafish
Match: pde4d (phosphodiesterase 4D, cAMP-specific [Source:ZFIN;Acc:ZDB-GENE-081105-16])

HSP 1 Score: 573.933 bits (1478), Expect = 0.000e+0
Identity = 281/543 (51.75%), Postives = 380/543 (69.98%), Query Frame = 3

Query: 1371 ATSRRGSLYIFRNADDVIITPFAQILASLRKVRANFMLITNITSNDEKKNKLDSINSPKIEENCSTNNKNITESHEKVAQETLNELEWCLNRLENIQTHRSVSDMASTKFKQIINRELSQFADSSKSGHQISDYICKTFLDSQLDDSIPEASSFERDIDDRKGKGKLESVRRSTKLVKASTEPVLNNSNLVTDSVLNASFVIEAPENDEDSETDVPLHGVHVANEEEVSKILDSDLKKWGMNLFSFADVTADQPLAVVSYTIFKDLNLINKFQIDSKTLVQFLIKAERSYRNTVPYHNNMHAADVTQSANVLLAGQALENVFSDLEILSVIFASIIHDMDHPGVTNQYLVNTNNELATLYNDNSVLENHHLAMAFSLLAKEECDFLATLSKRHRQSMRRMVIDMVLATDMSKHMTLLADLKTMVETKKVAGSGILTLDTYTDRIQILQNLVHCADLSNPTKPLHIYQKWIDRVMEEFYLQGDKERESELEISPMCDRQTASLEKSQVSFIDFIVHPLWETWSELVYPDTQGMLEALEENRQFY 2999
            + SR  S+    + DD+I+TPFAQ+LASLR VR NF  +TN+        +    N P I +   T      E+++K+A ETL EL+WCL++LE +QT  SVS+MAS KFK+++NREL+  ++ S+SG+Q+S+YI  TFLD Q +  +P   S +   D  K K  +  +    KL  +S+   L NSN                         +P  GV    E+E++K L+ D+ KWG+N+F  ++ + ++PL V+ YTIF++ +L+  F+I   T + +L+  E  Y   V YHNN+HAADVTQS +VLL+  ALE VF+DLEIL+ IFAS IHD+DHPGV+NQ+L+NTN+ELA +YND+SVLENHHLA+ F LL +E CD    L+K+ RQS+R+MVID+VLATDMSKHM LLADLKTMVETKKV  SG+L LD Y+DRIQ+LQN+VHCADLSNPTKPL +Y++W DR+MEEF+ QGD+ERE  +EISPMCD+  AS+EKSQV FID+IVHPLWETW++LV+PD Q +L+ LE+NR++Y
Sbjct:   54 SMSRNSSIASDIHGDDMIVTPFAQVLASLRTVRNNFAALTNVQQERSNNKRSPMCNPPPITKTSYTE-----EAYQKLATETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISSTFLDKQNEVEMPSPQSQK---DKEKKKRPMSQISGVKKLTHSSS---LTNSN-------------------------IPRFGVKTETEDELAKELE-DVNKWGLNVFKVSEFSGNRPLTVMMYTIFQERDLLKTFKIPLDTFITYLMTLEDHYHADVAYHNNIHAADVTQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFSQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWY 559

[Close]

BLAST of Phosphodiesterase vs. Ensembl Zebrafish
Match: BX510928.2 (phosphodiesterase 4D, cAMP-specific [Source:NCBI gene;Acc:566998])

HSP 1 Score: 569.311 bits (1466), Expect = 0.000e+0
Identity = 281/543 (51.75%), Postives = 381/543 (70.17%), Query Frame = 3

Query: 1371 ATSRRGSLYIFRNADDVIITPFAQILASLRKVRANFMLITNITSNDEKKNKLDSINSPKIEENCSTNNKNITESHEKVAQETLNELEWCLNRLENIQTHRSVSDMASTKFKQIINRELSQFADSSKSGHQISDYICKTFLDSQLDDSIPEASSFERDIDDRKGKGKLESVRRSTKLVKASTEPVLNNSNLVTDSVLNASFVIEAPENDEDSETDVPLHGVHVANEEEVSKILDSDLKKWGMNLFSFADVTADQPLAVVSYTIFKDLNLINKFQIDSKTLVQFLIKAERSYRNTVPYHNNMHAADVTQSANVLLAGQALENVFSDLEILSVIFASIIHDMDHPGVTNQYLVNTNNELATLYNDNSVLENHHLAMAFSLLAKEECDFLATLSKRHRQSMRRMVIDMVLATDMSKHMTLLADLKTMVETKKVAGSGILTLDTYTDRIQILQNLVHCADLSNPTKPLHIYQKWIDRVMEEFYLQGDKERESELEISPMCDRQTASLEKSQVSFIDFIVHPLWETWSELVYPDTQGMLEALEENRQFY 2999
            + SR  S+    + DD+I+TPFAQ+LASLR VR NF  +TN+   +   NK D +  P +            E+++K+A ETL EL+WCL++LE +QT  SVS+MAS KFK+++NREL+  ++ S+SG+Q+S+YI  TFLD Q +  +P   S +   D  K K  +  +    KL  +S+   L NSN                         +P  GV    E+E++K L+ D+ KWG+N+F  ++ + ++PL V+ YTIF++ +L+  F+I   T + +L+  E  Y   V YHNN+HAADVTQS +VLL+  ALE VF+DLEIL+ IFAS IHD+DHPGV+NQ+L+NTN+ELA +YND+SVLENHHLA+ F LL +E CD    L+K+ RQS+R+MVID+VLATDMSKHM LLADLKTMVETKKV  SG+L LD Y+DRIQ+LQN+VHCADLSNPTKPL +Y++W DR+MEEF+ QGD+ERE  +EISPMCD+  AS+EKSQV FID+IVHPLWETW++LV+PD Q +L+ LE+NR++Y
Sbjct:   73 SMSRNSSIASDIHGDDMIVTPFAQVLASLRTVRNNFAALTNV-QQERSNNKSDRL-PPSLPPE---------EAYQKLATETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISSTFLDKQNEVEMPSPQSQK---DKEKKKRPMSQISGVKKLTHSSS---LTNSN-------------------------IPRFGVKTETEDELAKELE-DVNKWGLNVFKVSEFSGNRPLTVMMYTIFQERDLLKTFKIPLDTFITYLMTLEDHYHADVAYHNNIHAADVTQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFSQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWY 572

[Close]

BLAST of Phosphodiesterase vs. Ensembl Zebrafish
Match: pde4cb (phosphodiesterase 4C, cAMP-specific b [Source:ZFIN;Acc:ZDB-GENE-030131-4075])

HSP 1 Score: 552.362 bits (1422), Expect = 0.000e+0
Identity = 287/598 (47.99%), Postives = 398/598 (66.56%), Query Frame = 3

Query: 1269 SVFHKSIRFDDEN--------MDYN-SSFSVKRQNSRFRKPFV------------ATSRRGSLYIFRNADDVIITPFAQILASLRKVRANFMLITNITSNDEKKNKLDSINSPKIEENCSTNNKNITESHEKVAQETLNELEWCLNRLENIQTHRSVSDMASTKFKQIINRELSQFADSSKSGHQISDYICKTFLDSQLDDSIPEASSFERDIDDRKGKGKLESVRRSTKLVKASTEPVLNNSNLVTDSVLNASFVIEAPENDEDSETDVPLHGVHVANEEEVSKILDSDLKKWGMNLFSFADVTADQPLAVVSYTIFKDLNLINKFQIDSKTLVQFLIKAERSYRNTVPYHNNMHAADVTQSANVLLAGQALENVFSDLEILSVIFASIIHDMDHPGVTNQYLVNTNNELATLYNDNSVLENHHLAMAFSLLAKEECDFLATLSKRHRQSMRRMVIDMVLATDMSKHMTLLADLKTMVETKKVAGSGILTLDTYTDRIQILQNLVHCADLSNPTKPLHIYQKWIDRVMEEFYLQGDKERESELEISPMCDRQTASLEKSQVSFIDFIVHPLWETWSELVYPDTQGMLEALEENRQFY 2999
            S FHK  RFD EN        +D + SS  V + NS+ R+ F+              SR  S     + +D+I+TPFAQ+LASLR VR N   +T++    ++ NK  S  +P  +  C TN  +  E+++K+  ETL EL+WCL++LE +QT  SVS+MAS KFK+++NREL+Q +++S+SG+Q+S++I  T L  Q D  +  A+  E     R+   ++  VR      K S  P L                           T +P  GV+  +E  ++K L+ DL +WG+++F  A+ + ++PL V+ YTIF++ +L+  F+I S T + FL+  E  Y   V YHNN+HAADV QS +VLL+  ALE+VF+DLEI++ +FAS IHD+DHPGVTNQ+L+NTN+ELA +YND SVLENHHLA+ F LL +E CD    LSK+ RQS+R+M IDMVLATDMSKHM  LADLKTMVETKKV   G+L LD Y+DRIQ+LQN+VHCADLSNPTKPL +Y+KW DR+M EF+ QGD+ER+  +++SPMCD+ TAS+E +QV FID+I+HPLWETW++LV+PD Q +L+ LE+NR++Y
Sbjct:   64 SSFHK--RFDVENGLSMGRSSLDPSPSSGLVLQANSQRRESFLYRSDSDFDLSPKTMSRNSSTASELHGEDMIVTPFAQVLASLRTVRGNVAALTHM---QDRSNKRPSGTNP--QSACKTNLSD--EAYQKLTVETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTQLSETSRSGNQVSEFIASTILQKQYDVELLSAACKEEK--KRRPMSQISGVR------KLSPSPSL-------------------------PPTCIPRFGVNTQHESLLAKELE-DLDRWGIDIFKIAEYSGNRPLTVMMYTIFQERDLLKTFKIPSDTFLTFLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEDVFTDLEIMAALFASAIHDVDHPGVTNQFLINTNSELALMYNDASVLENHHLAVGFKLLQEENCDIFCNLSKKQRQSLRQMTIDMVLATDMSKHMNFLADLKTMVETKKVTSQGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLELYRKWTDRIMVEFFSQGDRERDKGIDVSPMCDKHTASMENTQVGFIDYIIHPLWETWADLVHPDAQDILDTLEDNREWY 618

[Close]

BLAST of Phosphodiesterase vs. Ensembl Zebrafish
Match: pde4ca (phosphodiesterase 4C, cAMP-specific a [Source:ZFIN;Acc:ZDB-GENE-070912-373])

HSP 1 Score: 551.206 bits (1419), Expect = 0.000e+0
Identity = 273/554 (49.28%), Postives = 384/554 (69.31%), Query Frame = 3

Query: 1338 RQNSRFRKPFVATSRRGSLYIFRNADDVIITPFAQILASLRKVRANFMLITNITSNDEKKNKLDSINSPKIEENCSTNNKNITESHEKVAQETLNELEWCLNRLENIQTHRSVSDMASTKFKQIINRELSQFADSSKSGHQISDYICKTFLDSQLDDSIPEASSFERDIDDRKGKGKLESVRRSTKLVKASTEPVLNNSNLVTDSVLNASFVIEAPENDEDSETDVPLHGVHVANEEEVSKILDSDLKKWGMNLFSFADVTADQPLAVVSYTIFKDLNLINKFQIDSKTLVQFLIKAERSYRNTVPYHNNMHAADVTQSANVLLAGQALENVFSDLEILSVIFASIIHDMDHPGVTNQYLVNTNNELATLYNDNSVLENHHLAMAFSLLAKEECDFLATLSKRHRQSMRRMVIDMVLATDMSKHMTLLADLKTMVETKKVAGSGILTLDTYTDRIQILQNLVHCADLSNPTKPLHIYQKWIDRVMEEFYLQGDKERESELEISPMCDRQTASLEKSQVSFIDFIVHPLWETWSELVYPDTQGMLEALEENRQFY 2999
            R +S F     A SR  S     + +D+I+TPFAQ+LASLR VR+NF ++T+    D   +K  + N+P     C T+     E  +K+A ETL+EL+WCL +LE ++T  SVS+MAS KFK+++NREL+Q +++SKSG+Q+S+YI  TFL+ Q D  I    S E++   ++   ++  V++ T           ++SN+   S+                    P  GV    E+ ++K L+ D  +WG+++F  ++ + ++PL V  YT F++ +L+  F+I   T + ++   E +YR+ V YHN++HAADV QS +VLL+  ALE VF+DLEIL+ +FAS IHD+DHPGV+NQ+L+NTN+ELA +YND+SVLENHHLA+ F LL +E CD    L+K+ RQS+R+MVIDMVLATDMSKHM LLADLKTMVETKKV   G+L LD Y+DRIQ+LQN+VHCADLSNPTKPL +Y++W DR+M EF+ QGD+ER+  +EISPMCD+  AS+EKSQV FID+IVHPLWETW++LV+PD Q +L+ LE+NR++Y
Sbjct:   87 RSDSDFDLSPKAMSRNSSTASELHGEDMIVTPFAQVLASLRTVRSNFAVLTH--QQDRVPSKKSTGNNPP--SMCKTSLPE--EPFQKLAVETLDELDWCLEQLETLKTRHSVSEMASNKFKRMLNRELTQLSETSKSGNQVSEYISSTFLEKQHDMDIMSTPSKEKE-KKKRPMSQISGVKKPT-----------HSSNIAPSSI--------------------PRFGVSTNREDLLAKELE-DFDRWGVDMFKISECSGNRPLTVAMYTTFQERDLLKSFKIPVDTFINYMTALEENYRSDVAYHNSIHAADVVQSTHVLLSTPALEAVFTDLEILAAMFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDMVLATDMSKHMNLLADLKTMVETKKVTSLGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLELYRQWTDRIMVEFFTQGDRERDKGMEISPMCDKHNASIEKSQVGFIDYIVHPLWETWADLVHPDAQEILDTLEDNREWY 601

[Close]

BLAST of Phosphodiesterase vs. Ensembl Xenopus
Match: PDE4D (phosphodiesterase 4D [Source:NCBI gene;Acc:100496479])

HSP 1 Score: 578.556 bits (1490), Expect = 0.000e+0
Identity = 288/559 (51.52%), Postives = 390/559 (69.77%), Query Frame = 3

Query: 1338 RQNSRFRKPFVATSRRGSLYIF-----RNADDVIITPFAQILASLRKVRANFMLITNITSNDEKKNKLDSINSPKIEENCSTNNKNITESHEKVAQETLNELEWCLNRLENIQTHRSVSDMASTKFKQIINRELSQFADSSKSGHQISDYICKTFLDSQLDDSIPEASSFERDIDDRKGKGKLESVRRSTKLVKASTEPVLNNSNLVTDSVLNASFVIEAPENDEDSETDVPLHGVHVANEEEVSKILDSDLKKWGMNLFSFADVTADQPLAVVSYTIFKDLNLINKFQIDSKTLVQFLIKAERSYRNTVPYHNNMHAADVTQSANVLLAGQALENVFSDLEILSVIFASIIHDMDHPGVTNQYLVNTNNELATLYNDNSVLENHHLAMAFSLLAKEECDFLATLSKRHRQSMRRMVIDMVLATDMSKHMTLLADLKTMVETKKVAGSGILTLDTYTDRIQILQNLVHCADLSNPTKPLHIYQKWIDRVMEEFYLQGDKERESELEISPMCDRQTASLEKSQVSFIDFIVHPLWETWSELVYPDTQGMLEALEENRQFY 2999
            R +S +     + SR  S+ +      R+ DD+I+TPFAQ+LASLR VR NF  +TN+   D   N   S + P +   C  N KNI E+++K+A ETL EL+WCL++LE +QT  SVS+MAS KFK+++NREL+  ++ S+SG+Q+S+YI  TFLD Q +  +P  +  E++    K K  +  +    KL+ +S+   L NSN                         +P  GV   NEE ++K L+ D+ KWG+N+F  A+ + ++PL VV +TIF++  ++  F+I   TL+ +L+  E  Y   V YHNN+HAADV QS +VLL+  ALE VF+DLEIL+ IFAS IHD+DHPGV+NQ+L+NTN+ELA +YND+SVLENHHLA+ F LL +E CD    L+K+ RQ +R+MVID+VLATDMSKHM LLADLKTMVETKKV  SG+L LD Y+DRIQ+LQN+VHCADLSNPTKPL +Y+ W DR+MEEF+ QGD+ERE  +EISPMCD+  AS+EKSQV FID+IVHPLWETW++LV+PD Q +L+ LE+NR++Y
Sbjct:   84 RSDSDYELSPKSMSRNSSIAMLTSMFCRHGDDLIVTPFAQVLASLRTVRNNFAALTNL--QDRAPNCATSDSPPTM---CKRNIKNIKEAYQKLAGETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEMPSPAQKEKE----KKKRPMSQISGVKKLMHSSS---LTNSN-------------------------IPRFGVKSENEECLAKELE-DVNKWGLNIFKVAEFSGNRPLTVVMHTIFQEREMLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVAQSTHVLLSSPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQLLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLPLYRHWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWY 604

[Close]

BLAST of Phosphodiesterase vs. Ensembl Xenopus
Match: PDE4D (phosphodiesterase 4D [Source:NCBI gene;Acc:100496479])

HSP 1 Score: 567 bits (1460), Expect = 0.000e+0
Identity = 285/556 (51.26%), Postives = 387/556 (69.60%), Query Frame = 3

Query: 1338 RQNSRFRKPFVATSRRGSLYIFRNADDVIITPFAQILASLRKVRANFMLITNITSNDEKKNKLDSI-NSPKIEENCSTNNKNITE-SHEKVAQETLNELEWCLNRLENIQTHRSVSDMASTKFKQIINRELSQFADSSKSGHQISDYICKTFLDSQLDDSIPEASSFERDIDDRKGKGKLESVRRSTKLVKASTEPVLNNSNLVTDSVLNASFVIEAPENDEDSETDVPLHGVHVANEEEVSKILDSDLKKWGMNLFSFADVTADQPLAVVSYTIFKDLNLINKFQIDSKTLVQFLIKAERSYRNTVPYHNNMHAADVTQSANVLLAGQALENVFSDLEILSVIFASIIHDMDHPGVTNQYLVNTNNELATLYNDNSVLENHHLAMAFSLLAKEECDFLATLSKRHRQSMRRMVIDMVLATDMSKHMTLLADLKTMVETKKVAGSGILTLDTYTDRIQILQNLVHCADLSNPTKPLHIYQKWIDRVMEEFYLQGDKERESELEISPMCDRQTASLEKSQVSFIDFIVHPLWETWSELVYPDTQGMLEALEENRQFY 2999
            R +S +     + SR  S+    + DD+I+TPFAQ+LASLR VR NF  +TN+   D   +K  ++ N P I      N   I E +++K+A ETL EL+WCL++LE +QT  SVS+MAS KFK+++NREL+  ++ S+SG+Q+S+YI  TFLD Q +  +P  +  E++    K K  +  +    KL+ +S+   L NSN                         +P  GV   NEE ++K L+ D+ KWG+N+F  A+ + ++PL VV +TIF++  ++  F+I   TL+ +L+  E  Y   V YHNN+HAADV QS +VLL+  ALE VF+DLEIL+ IFAS IHD+DHPGV+NQ+L+NTN+ELA +YND+SVLENHHLA+ F LL +E CD    L+K+ RQ +R+MVID+VLATDMSKHM LLADLKTMVETKKV  SG+L LD Y+DRIQ+LQN+VHCADLSNPTKPL +Y+ W DR+MEEF+ QGD+ERE  +EISPMCD+  AS+EKSQV FID+IVHPLWETW++LV+PD Q +L+ LE+NR++Y
Sbjct:   64 RSDSDYELSPKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNL--QDRAPSKRSTMCNQPSI------NKATIPEEAYQKLAGETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEMPSPAQKEKE----KKKRPMSQISGVKKLMHSSS---LTNSN-------------------------IPRFGVKSENEECLAKELE-DVNKWGLNIFKVAEFSGNRPLTVVMHTIFQEREMLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVAQSTHVLLSSPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQLLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLPLYRHWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWY 578

[Close]

BLAST of Phosphodiesterase vs. Ensembl Xenopus
Match: PDE4D (phosphodiesterase 4D [Source:NCBI gene;Acc:100496479])

HSP 1 Score: 566.614 bits (1459), Expect = 0.000e+0
Identity = 285/556 (51.26%), Postives = 387/556 (69.60%), Query Frame = 3

Query: 1338 RQNSRFRKPFVATSRRGSLYIFRNADDVIITPFAQILASLRKVRANFMLITNITSNDEKKNKLDSI-NSPKIEENCSTNNKNITE-SHEKVAQETLNELEWCLNRLENIQTHRSVSDMASTKFKQIINRELSQFADSSKSGHQISDYICKTFLDSQLDDSIPEASSFERDIDDRKGKGKLESVRRSTKLVKASTEPVLNNSNLVTDSVLNASFVIEAPENDEDSETDVPLHGVHVANEEEVSKILDSDLKKWGMNLFSFADVTADQPLAVVSYTIFKDLNLINKFQIDSKTLVQFLIKAERSYRNTVPYHNNMHAADVTQSANVLLAGQALENVFSDLEILSVIFASIIHDMDHPGVTNQYLVNTNNELATLYNDNSVLENHHLAMAFSLLAKEECDFLATLSKRHRQSMRRMVIDMVLATDMSKHMTLLADLKTMVETKKVAGSGILTLDTYTDRIQILQNLVHCADLSNPTKPLHIYQKWIDRVMEEFYLQGDKERESELEISPMCDRQTASLEKSQVSFIDFIVHPLWETWSELVYPDTQGMLEALEENRQFY 2999
            R +S +     + SR  S+    + DD+I+TPFAQ+LASLR VR NF  +TN+   D   +K  ++ N P I      N   I E +++K+A ETL EL+WCL++LE +QT  SVS+MAS KFK+++NREL+  ++ S+SG+Q+S+YI  TFLD Q +  +P  +  E++    K K  +  +    KL+ +S+   L NSN                         +P  GV   NEE ++K L+ D+ KWG+N+F  A+ + ++PL VV +TIF++  ++  F+I   TL+ +L+  E  Y   V YHNN+HAADV QS +VLL+  ALE VF+DLEIL+ IFAS IHD+DHPGV+NQ+L+NTN+ELA +YND+SVLENHHLA+ F LL +E CD    L+K+ RQ +R+MVID+VLATDMSKHM LLADLKTMVETKKV  SG+L LD Y+DRIQ+LQN+VHCADLSNPTKPL +Y+ W DR+MEEF+ QGD+ERE  +EISPMCD+  AS+EKSQV FID+IVHPLWETW++LV+PD Q +L+ LE+NR++Y
Sbjct:   69 RSDSDYELSPKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNL--QDRAPSKRSTMCNQPSI------NKATIPEEAYQKLAGETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEMPSPAQKEKE----KKKRPMSQISGVKKLMHSSS---LTNSN-------------------------IPRFGVKSENEECLAKELE-DVNKWGLNIFKVAEFSGNRPLTVVMHTIFQEREMLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVAQSTHVLLSSPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQLLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLPLYRHWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWY 583

[Close]

Query: 1338 RQNSRFRKPFVATSRRGSLYIFRNADDVIITPFAQILASLRKVRANFMLITNITSNDEKKNKLDSI-NSPKIEENCSTNNKNITE-SHEKVAQETLNELEWCLNRLENIQTHRSVSDMASTKFKQIINRELSQFADSSKSGHQISDYICKTFLDSQLDDSIPEASSFERDIDDRKGKGKLESVRRSTKLVKASTEPVLNNSNLVTDSVLNASFVIEAPENDEDSETDVPLHGVHVANEEEVSKILDSDLKKWGMNLFSFADVTADQPLAVVSYTIFKDLNLINKFQIDSKTLVQFLIKAERSYRNTVPYHNNMHAADVTQSANVLLAGQALENVFSDLEILSVIFASIIHDMDHPGVTNQYLVNTNNELATLYNDNSVLENHHLAMAFSLLAKEECDFLATLSKRHRQSMRRMVIDMVLATDMSKHMTLLADLKTMVETKKVAGSGILTLDTYTDRIQILQNLVHCADLSNPTKPLHIYQKWIDRVMEEFYLQGDKERESELEISPMCDRQTASLEKSQVSFIDFIVHPLWETWSELVYPDTQGMLEALEENRQFY 2999
            R +S +     + SR  S+    + DD+I+TPFAQ+LASLR VR NF  +TN+   D   +K  ++ N P I      N   I E +++K+A ETL EL+WCL++LE +QT  SVS+MAS KFK+++NREL+  ++ S+SG+Q+S+YI  TFLD Q +  +P  +  E++    K K  +  +    KL+ +S+   L NSN                         +P  GV   NEE ++K L+ D+ KWG+N+F  A+ + ++PL VV +TIF++  ++  F+I   TL+ +L+  E  Y   V YHNN+HAADV QS +VLL+  ALE VF+DLEIL+ IFAS IHD+DHPGV+NQ+L+NTN+ELA +YND+SVLENHHLA+ F LL +E CD    L+K+ RQ +R+MVID+VLATDMSKHM LLADLKTMVETKKV  SG+L LD Y+DRIQ+LQN+VHCADLSNPTKPL +Y+ W DR+MEEF+ QGD+ERE  +EISPMCD+  AS+EKSQV FID+IVHPLWETW++LV+PD Q +L+ LE+NR++Y
Sbjct:   84 RSDSDYELSPKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNL--QDRAPSKRSTMCNQPSI------NKATIPEEAYQKLAGETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEMPSPAQKEKE----KKKRPMSQISGVKKLMHSSS---LTNSN-------------------------IPRFGVKSENEECLAKELE-DVNKWGLNIFKVAEFSGNRPLTVVMHTIFQEREMLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVAQSTHVLLSSPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQLLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLPLYRHWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWY 598

[Close]

BLAST of Phosphodiesterase vs. Ensembl Xenopus
Match: PDE4D (phosphodiesterase 4D [Source:NCBI gene;Acc:100496479])

HSP 1 Score: 566.229 bits (1458), Expect = 0.000e+0
Identity = 285/556 (51.26%), Postives = 387/556 (69.60%), Query Frame = 3

Query: 1338 RQNSRFRKPFVATSRRGSLYIFRNADDVIITPFAQILASLRKVRANFMLITNITSNDEKKNKLDSI-NSPKIEENCSTNNKNITE-SHEKVAQETLNELEWCLNRLENIQTHRSVSDMASTKFKQIINRELSQFADSSKSGHQISDYICKTFLDSQLDDSIPEASSFERDIDDRKGKGKLESVRRSTKLVKASTEPVLNNSNLVTDSVLNASFVIEAPENDEDSETDVPLHGVHVANEEEVSKILDSDLKKWGMNLFSFADVTADQPLAVVSYTIFKDLNLINKFQIDSKTLVQFLIKAERSYRNTVPYHNNMHAADVTQSANVLLAGQALENVFSDLEILSVIFASIIHDMDHPGVTNQYLVNTNNELATLYNDNSVLENHHLAMAFSLLAKEECDFLATLSKRHRQSMRRMVIDMVLATDMSKHMTLLADLKTMVETKKVAGSGILTLDTYTDRIQILQNLVHCADLSNPTKPLHIYQKWIDRVMEEFYLQGDKERESELEISPMCDRQTASLEKSQVSFIDFIVHPLWETWSELVYPDTQGMLEALEENRQFY 2999
            R +S +     + SR  S+    + DD+I+TPFAQ+LASLR VR NF  +TN+   D   +K  ++ N P I      N   I E +++K+A ETL EL+WCL++LE +QT  SVS+MAS KFK+++NREL+  ++ S+SG+Q+S+YI  TFLD Q +  +P  +  E++    K K  +  +    KL+ +S+   L NSN                         +P  GV   NEE ++K L+ D+ KWG+N+F  A+ + ++PL VV +TIF++  ++  F+I   TL+ +L+  E  Y   V YHNN+HAADV QS +VLL+  ALE VF+DLEIL+ IFAS IHD+DHPGV+NQ+L+NTN+ELA +YND+SVLENHHLA+ F LL +E CD    L+K+ RQ +R+MVID+VLATDMSKHM LLADLKTMVETKKV  SG+L LD Y+DRIQ+LQN+VHCADLSNPTKPL +Y+ W DR+MEEF+ QGD+ERE  +EISPMCD+  AS+EKSQV FID+IVHPLWETW++LV+PD Q +L+ LE+NR++Y
Sbjct:   71 RSDSDYELSPKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNL--QDRAPSKRSTMCNQPSI------NKATIPEEAYQKLAGETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEMPSPAQKEKE----KKKRPMSQISGVKKLMHSSS---LTNSN-------------------------IPRFGVKSENEECLAKELE-DVNKWGLNIFKVAEFSGNRPLTVVMHTIFQEREMLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVAQSTHVLLSSPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQLLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLPLYRHWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWY 585

[Close]

BLAST of Phosphodiesterase vs. Ensembl Mouse
Match: Pde4d (phosphodiesterase 4D, cAMP specific [Source:MGI Symbol;Acc:MGI:99555])

HSP 1 Score: 568.155 bits (1463), Expect = 0.000e+0
Identity = 281/544 (51.65%), Postives = 386/544 (70.96%), Query Frame = 3

Query: 1371 ATSRRGSLYIFRNADDVIITPFAQILASLRKVRANFMLITNITSNDEKKNKLDSINSPKIEENCSTNNKNITE-SHEKVAQETLNELEWCLNRLENIQTHRSVSDMASTKFKQIINRELSQFADSSKSGHQISDYICKTFLDSQLDDSIPEASSFERDIDDRKGKGKLESVRRSTKLVKASTEPVLNNSNLVTDSVLNASFVIEAPENDEDSETDVPLHGVHVANEEEVSKILDSDLKKWGMNLFSFADVTADQPLAVVSYTIFKDLNLINKFQIDSKTLVQFLIKAERSYRNTVPYHNNMHAADVTQSANVLLAGQALENVFSDLEILSVIFASIIHDMDHPGVTNQYLVNTNNELATLYNDNSVLENHHLAMAFSLLAKEECDFLATLSKRHRQSMRRMVIDMVLATDMSKHMTLLADLKTMVETKKVAGSGILTLDTYTDRIQILQNLVHCADLSNPTKPLHIYQKWIDRVMEEFYLQGDKERESELEISPMCDRQTASLEKSQVSFIDFIVHPLWETWSELVYPDTQGMLEALEENRQFY 2999
            + SR  S+    + DD+I+TPFAQ+LASLR VR NF  +TN+      +++  S  SP   +  S N   ITE +++K+A ETL EL+WCL++LE +QT  SVS+MAS KFK+++NREL+  ++ S+SG+Q+S+YI  TFLD Q +  IP  +  E++    K K  +  +    KL+ +S+   L NS                          +P  GV    E+ ++K L+ D+ KWG+++F  A+++ ++PL V+ +TIF++ +L+  F+I   TL+ +L+  E  Y   V YHNN+HAADV QS +VLL+  ALE VF+DLEIL+ IFAS IHD+DHPGV+NQ+L+NTN+ELA +YND+SVLENHHLA+ F LL +E CD    L+K+ RQS+R+MVID+VLATDMSKHM LLADLKTMVETKKV  SG+L LD Y+DRIQ+LQN+VHCADLSNPTKPL +Y++W DR+MEEF+ QGD+ERE  +EISPMCD+  AS+EKSQV FID+IVHPLWETW++LV+PD Q +L+ LE+NR++Y
Sbjct:  144 SMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNL------QDRAPSKRSPMCNQP-SINKATITEEAYQKLASETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKE----KKKRPMSQISGVKKLMHSSS---LTNSC-------------------------IPRFGVKTEQEDVLAKELE-DVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWY 647

[Close]

Query: 1371 ATSRRGSLYIFRNADDVIITPFAQILASLRKVRANFMLITNITSNDEKKNKLDSINSPKIEENCSTNNKNITE-SHEKVAQETLNELEWCLNRLENIQTHRSVSDMASTKFKQIINRELSQFADSSKSGHQISDYICKTFLDSQLDDSIPEASSFERDIDDRKGKGKLESVRRSTKLVKASTEPVLNNSNLVTDSVLNASFVIEAPENDEDSETDVPLHGVHVANEEEVSKILDSDLKKWGMNLFSFADVTADQPLAVVSYTIFKDLNLINKFQIDSKTLVQFLIKAERSYRNTVPYHNNMHAADVTQSANVLLAGQALENVFSDLEILSVIFASIIHDMDHPGVTNQYLVNTNNELATLYNDNSVLENHHLAMAFSLLAKEECDFLATLSKRHRQSMRRMVIDMVLATDMSKHMTLLADLKTMVETKKVAGSGILTLDTYTDRIQILQNLVHCADLSNPTKPLHIYQKWIDRVMEEFYLQGDKERESELEISPMCDRQTASLEKSQVSFIDFIVHPLWETWSELVYPDTQGMLEALEENRQFY 2999
            + SR  S+    + DD+I+TPFAQ+LASLR VR NF  +TN+      +++  S  SP   +  S N   ITE +++K+A ETL EL+WCL++LE +QT  SVS+MAS KFK+++NREL+  ++ S+SG+Q+S+YI  TFLD Q +  IP  +  E++    K K  +  +    KL+ +S+   L NS                          +P  GV    E+ ++K L+ D+ KWG+++F  A+++ ++PL V+ +TIF++ +L+  F+I   TL+ +L+  E  Y   V YHNN+HAADV QS +VLL+  ALE VF+DLEIL+ IFAS IHD+DHPGV+NQ+L+NTN+ELA +YND+SVLENHHLA+ F LL +E CD    L+K+ RQS+R+MVID+VLATDMSKHM LLADLKTMVETKKV  SG+L LD Y+DRIQ+LQN+VHCADLSNPTKPL +Y++W DR+MEEF+ QGD+ERE  +EISPMCD+  AS+EKSQV FID+IVHPLWETW++LV+PD Q +L+ LE+NR++Y
Sbjct:  144 SMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNL------QDRAPSKRSPMCNQP-SINKATITEEAYQKLASETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKE----KKKRPMSQISGVKKLMHSSS---LTNSC-------------------------IPRFGVKTEQEDVLAKELE-DVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWY 647

[Close]

BLAST of Phosphodiesterase vs. Ensembl Mouse
Match: Pde4d (phosphodiesterase 4D, cAMP specific [Source:MGI Symbol;Acc:MGI:99555])

HSP 1 Score: 567.77 bits (1462), Expect = 0.000e+0
Identity = 281/544 (51.65%), Postives = 386/544 (70.96%), Query Frame = 3

Query: 1371 ATSRRGSLYIFRNADDVIITPFAQILASLRKVRANFMLITNITSNDEKKNKLDSINSPKIEENCSTNNKNITE-SHEKVAQETLNELEWCLNRLENIQTHRSVSDMASTKFKQIINRELSQFADSSKSGHQISDYICKTFLDSQLDDSIPEASSFERDIDDRKGKGKLESVRRSTKLVKASTEPVLNNSNLVTDSVLNASFVIEAPENDEDSETDVPLHGVHVANEEEVSKILDSDLKKWGMNLFSFADVTADQPLAVVSYTIFKDLNLINKFQIDSKTLVQFLIKAERSYRNTVPYHNNMHAADVTQSANVLLAGQALENVFSDLEILSVIFASIIHDMDHPGVTNQYLVNTNNELATLYNDNSVLENHHLAMAFSLLAKEECDFLATLSKRHRQSMRRMVIDMVLATDMSKHMTLLADLKTMVETKKVAGSGILTLDTYTDRIQILQNLVHCADLSNPTKPLHIYQKWIDRVMEEFYLQGDKERESELEISPMCDRQTASLEKSQVSFIDFIVHPLWETWSELVYPDTQGMLEALEENRQFY 2999
            + SR  S+    + DD+I+TPFAQ+LASLR VR NF  +TN+      +++  S  SP   +  S N   ITE +++K+A ETL EL+WCL++LE +QT  SVS+MAS KFK+++NREL+  ++ S+SG+Q+S+YI  TFLD Q +  IP  +  E++    K K  +  +    KL+ +S+   L NS                          +P  GV    E+ ++K L+ D+ KWG+++F  A+++ ++PL V+ +TIF++ +L+  F+I   TL+ +L+  E  Y   V YHNN+HAADV QS +VLL+  ALE VF+DLEIL+ IFAS IHD+DHPGV+NQ+L+NTN+ELA +YND+SVLENHHLA+ F LL +E CD    L+K+ RQS+R+MVID+VLATDMSKHM LLADLKTMVETKKV  SG+L LD Y+DRIQ+LQN+VHCADLSNPTKPL +Y++W DR+MEEF+ QGD+ERE  +EISPMCD+  AS+EKSQV FID+IVHPLWETW++LV+PD Q +L+ LE+NR++Y
Sbjct:   75 SMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNL------QDRAPSKRSPMCNQP-SINKATITEEAYQKLASETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKE----KKKRPMSQISGVKKLMHSSS---LTNSC-------------------------IPRFGVKTEQEDVLAKELE-DVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWY 578

[Close]

BLAST of Phosphodiesterase vs. Ensembl Mouse
Match: Pde4d (phosphodiesterase 4D, cAMP specific [Source:MGI Symbol;Acc:MGI:99555])

HSP 1 Score: 567.385 bits (1461), Expect = 0.000e+0
Identity = 281/544 (51.65%), Postives = 386/544 (70.96%), Query Frame = 3

Query: 1371 ATSRRGSLYIFRNADDVIITPFAQILASLRKVRANFMLITNITSNDEKKNKLDSINSPKIEENCSTNNKNITE-SHEKVAQETLNELEWCLNRLENIQTHRSVSDMASTKFKQIINRELSQFADSSKSGHQISDYICKTFLDSQLDDSIPEASSFERDIDDRKGKGKLESVRRSTKLVKASTEPVLNNSNLVTDSVLNASFVIEAPENDEDSETDVPLHGVHVANEEEVSKILDSDLKKWGMNLFSFADVTADQPLAVVSYTIFKDLNLINKFQIDSKTLVQFLIKAERSYRNTVPYHNNMHAADVTQSANVLLAGQALENVFSDLEILSVIFASIIHDMDHPGVTNQYLVNTNNELATLYNDNSVLENHHLAMAFSLLAKEECDFLATLSKRHRQSMRRMVIDMVLATDMSKHMTLLADLKTMVETKKVAGSGILTLDTYTDRIQILQNLVHCADLSNPTKPLHIYQKWIDRVMEEFYLQGDKERESELEISPMCDRQTASLEKSQVSFIDFIVHPLWETWSELVYPDTQGMLEALEENRQFY 2999
            + SR  S+    + DD+I+TPFAQ+LASLR VR NF  +TN+      +++  S  SP   +  S N   ITE +++K+A ETL EL+WCL++LE +QT  SVS+MAS KFK+++NREL+  ++ S+SG+Q+S+YI  TFLD Q +  IP  +  E++    K K  +  +    KL+ +S+   L NS                          +P  GV    E+ ++K L+ D+ KWG+++F  A+++ ++PL V+ +TIF++ +L+  F+I   TL+ +L+  E  Y   V YHNN+HAADV QS +VLL+  ALE VF+DLEIL+ IFAS IHD+DHPGV+NQ+L+NTN+ELA +YND+SVLENHHLA+ F LL +E CD    L+K+ RQS+R+MVID+VLATDMSKHM LLADLKTMVETKKV  SG+L LD Y+DRIQ+LQN+VHCADLSNPTKPL +Y++W DR+MEEF+ QGD+ERE  +EISPMCD+  AS+EKSQV FID+IVHPLWETW++LV+PD Q +L+ LE+NR++Y
Sbjct:  151 SMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNL------QDRAPSKRSPMCNQP-SINKATITEEAYQKLASETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKE----KKKRPMSQISGVKKLMHSSS---LTNSC-------------------------IPRFGVKTEQEDVLAKELE-DVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWY 654

[Close]

Query: 1371 ATSRRGSLYIFRNADDVIITPFAQILASLRKVRANFMLITNITSNDEKKNKLDSINSPKIEENCSTNNKNITE-SHEKVAQETLNELEWCLNRLENIQTHRSVSDMASTKFKQIINRELSQFADSSKSGHQISDYICKTFLDSQLDDSIPEASSFERDIDDRKGKGKLESVRRSTKLVKASTEPVLNNSNLVTDSVLNASFVIEAPENDEDSETDVPLHGVHVANEEEVSKILDSDLKKWGMNLFSFADVTADQPLAVVSYTIFKDLNLINKFQIDSKTLVQFLIKAERSYRNTVPYHNNMHAADVTQSANVLLAGQALENVFSDLEILSVIFASIIHDMDHPGVTNQYLVNTNNELATLYNDNSVLENHHLAMAFSLLAKEECDFLATLSKRHRQSMRRMVIDMVLATDMSKHMTLLADLKTMVETKKVAGSGILTLDTYTDRIQILQNLVHCADLSNPTKPLHIYQKWIDRVMEEFYLQGDKERESELEISPMCDRQTASLEKSQVSFIDFIVHPLWETWSELVYPDTQGMLEALEENRQFY 2999
            + SR  S+    + DD+I+TPFAQ+LASLR VR NF  +TN+      +++  S  SP   +  S N   ITE +++K+A ETL EL+WCL++LE +QT  SVS+MAS KFK+++NREL+  ++ S+SG+Q+S+YI  TFLD Q +  IP  +  E++    K K  +  +    KL+ +S+   L NS                          +P  GV    E+ ++K L+ D+ KWG+++F  A+++ ++PL V+ +TIF++ +L+  F+I   TL+ +L+  E  Y   V YHNN+HAADV QS +VLL+  ALE VF+DLEIL+ IFAS IHD+DHPGV+NQ+L+NTN+ELA +YND+SVLENHHLA+ F LL +E CD    L+K+ RQS+R+MVID+VLATDMSKHM LLADLKTMVETKKV  SG+L LD Y+DRIQ+LQN+VHCADLSNPTKPL +Y++W DR+MEEF+ QGD+ERE  +EISPMCD+  AS+EKSQV FID+IVHPLWETW++LV+PD Q +L+ LE+NR++Y
Sbjct:  200 SMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNL------QDRAPSKRSPMCNQP-SINKATITEEAYQKLASETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKE----KKKRPMSQISGVKKLMHSSS---LTNSC-------------------------IPRFGVKTEQEDVLAKELE-DVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWY 703

[Close]

BLAST of Phosphodiesterase vs. UniProt/SwissProt
Match: sp|Q01063|PDE4D_MOUSE (cAMP-specific 3',5'-cyclic phosphodiesterase 4D OS=Mus musculus OX=10090 GN=Pde4d PE=1 SV=2)

HSP 1 Score: 568.155 bits (1463), Expect = 0.000e+0
Identity = 281/544 (51.65%), Postives = 386/544 (70.96%), Query Frame = 3

Query: 1371 ATSRRGSLYIFRNADDVIITPFAQILASLRKVRANFMLITNITSNDEKKNKLDSINSPKIEENCSTNNKNITE-SHEKVAQETLNELEWCLNRLENIQTHRSVSDMASTKFKQIINRELSQFADSSKSGHQISDYICKTFLDSQLDDSIPEASSFERDIDDRKGKGKLESVRRSTKLVKASTEPVLNNSNLVTDSVLNASFVIEAPENDEDSETDVPLHGVHVANEEEVSKILDSDLKKWGMNLFSFADVTADQPLAVVSYTIFKDLNLINKFQIDSKTLVQFLIKAERSYRNTVPYHNNMHAADVTQSANVLLAGQALENVFSDLEILSVIFASIIHDMDHPGVTNQYLVNTNNELATLYNDNSVLENHHLAMAFSLLAKEECDFLATLSKRHRQSMRRMVIDMVLATDMSKHMTLLADLKTMVETKKVAGSGILTLDTYTDRIQILQNLVHCADLSNPTKPLHIYQKWIDRVMEEFYLQGDKERESELEISPMCDRQTASLEKSQVSFIDFIVHPLWETWSELVYPDTQGMLEALEENRQFY 2999
            + SR  S+    + DD+I+TPFAQ+LASLR VR NF  +TN+      +++  S  SP   +  S N   ITE +++K+A ETL EL+WCL++LE +QT  SVS+MAS KFK+++NREL+  ++ S+SG+Q+S+YI  TFLD Q +  IP  +  E++    K K  +  +    KL+ +S+   L NS                          +P  GV    E+ ++K L+ D+ KWG+++F  A+++ ++PL V+ +TIF++ +L+  F+I   TL+ +L+  E  Y   V YHNN+HAADV QS +VLL+  ALE VF+DLEIL+ IFAS IHD+DHPGV+NQ+L+NTN+ELA +YND+SVLENHHLA+ F LL +E CD    L+K+ RQS+R+MVID+VLATDMSKHM LLADLKTMVETKKV  SG+L LD Y+DRIQ+LQN+VHCADLSNPTKPL +Y++W DR+MEEF+ QGD+ERE  +EISPMCD+  AS+EKSQV FID+IVHPLWETW++LV+PD Q +L+ LE+NR++Y
Sbjct:  144 SMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNL------QDRAPSKRSPMCNQP-SINKATITEEAYQKLASETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKE----KKKRPMSQISGVKKLMHSSS---LTNSC-------------------------IPRFGVKTEQEDVLAKELE-DVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWY 647

[Close]

BLAST of Phosphodiesterase vs. UniProt/SwissProt
Match: sp|Q08499|PDE4D_HUMAN (cAMP-specific 3',5'-cyclic phosphodiesterase 4D OS=Homo sapiens OX=9606 GN=PDE4D PE=1 SV=2)

HSP 1 Score: 567 bits (1460), Expect = 0.000e+0
Identity = 280/542 (51.66%), Postives = 386/542 (71.22%), Query Frame = 3

Query: 1377 SRRGSLYIFRNADDVIITPFAQILASLRKVRANFMLITNITSNDEKKNKLDSINSPKIEENCSTNNKNITE-SHEKVAQETLNELEWCLNRLENIQTHRSVSDMASTKFKQIINRELSQFADSSKSGHQISDYICKTFLDSQLDDSIPEASSFERDIDDRKGKGKLESVRRSTKLVKASTEPVLNNSNLVTDSVLNASFVIEAPENDEDSETDVPLHGVHVANEEEVSKILDSDLKKWGMNLFSFADVTADQPLAVVSYTIFKDLNLINKFQIDSKTLVQFLIKAERSYRNTVPYHNNMHAADVTQSANVLLAGQALENVFSDLEILSVIFASIIHDMDHPGVTNQYLVNTNNELATLYNDNSVLENHHLAMAFSLLAKEECDFLATLSKRHRQSMRRMVIDMVLATDMSKHMTLLADLKTMVETKKVAGSGILTLDTYTDRIQILQNLVHCADLSNPTKPLHIYQKWIDRVMEEFYLQGDKERESELEISPMCDRQTASLEKSQVSFIDFIVHPLWETWSELVYPDTQGMLEALEENRQFY 2999
            SR  S+    + DD+I+TPFAQ+LASLR VR NF  +TN+      +++  S  SP   +  S N   ITE +++K+A ETL EL+WCL++LE +QT  SVS+MAS KFK+++NREL+  ++ S+SG+Q+S++I  TFLD Q +  IP  +  E++    K K  +  +    KL+ +S+   L NS+                         +P  GV    E+ ++K L+ D+ KWG+++F  A+++ ++PL V+ +TIF++ +L+  F+I   TL+ +L+  E  Y   V YHNN+HAADV QS +VLL+  ALE VF+DLEIL+ IFAS IHD+DHPGV+NQ+L+NTN+ELA +YND+SVLENHHLA+ F LL +E CD    L+K+ RQS+R+MVID+VLATDMSKHM LLADLKTMVETKKV  SG+L LD Y+DRIQ+LQN+VHCADLSNPTKPL +Y++W DR+MEEF+ QGD+ERE  +EISPMCD+  AS+EKSQV FID+IVHPLWETW++LV+PD Q +L+ LE+NR++Y
Sbjct:  207 SRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNL------QDRAPSKRSPMCNQP-SINKATITEEAYQKLASETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEFISNTFLDKQHEVEIPSPTQKEKE----KKKRPMSQISGVKKLMHSSS---LTNSS-------------------------IPRFGVKTEQEDVLAKELE-DVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWY 708

[Close]

BLAST of Phosphodiesterase vs. UniProt/SwissProt
Match: sp|P14270|PDE4D_RAT (cAMP-specific 3',5'-cyclic phosphodiesterase 4D OS=Rattus norvegicus OX=10116 GN=Pde4d PE=1 SV=4)

HSP 1 Score: 565.844 bits (1457), Expect = 0.000e+0
Identity = 280/544 (51.47%), Postives = 385/544 (70.77%), Query Frame = 3

Query: 1371 ATSRRGSLYIFRNADDVIITPFAQILASLRKVRANFMLITNITSNDEKKNKLDSINSPKIEENCSTNNKNITE-SHEKVAQETLNELEWCLNRLENIQTHRSVSDMASTKFKQIINRELSQFADSSKSGHQISDYICKTFLDSQLDDSIPEASSFERDIDDRKGKGKLESVRRSTKLVKASTEPVLNNSNLVTDSVLNASFVIEAPENDEDSETDVPLHGVHVANEEEVSKILDSDLKKWGMNLFSFADVTADQPLAVVSYTIFKDLNLINKFQIDSKTLVQFLIKAERSYRNTVPYHNNMHAADVTQSANVLLAGQALENVFSDLEILSVIFASIIHDMDHPGVTNQYLVNTNNELATLYNDNSVLENHHLAMAFSLLAKEECDFLATLSKRHRQSMRRMVIDMVLATDMSKHMTLLADLKTMVETKKVAGSGILTLDTYTDRIQILQNLVHCADLSNPTKPLHIYQKWIDRVMEEFYLQGDKERESELEISPMCDRQTASLEKSQVSFIDFIVHPLWETWSELVYPDTQGMLEALEENRQFY 2999
            + SR  S+    + DD+I+TPFAQ+LASLR VR NF  +TN+      +++  S  SP   +  S N   ITE +++K+A ETL EL+WCL++LE +QT  SVS+MAS KFK+++NREL+  ++ S+SG+Q+S+YI  TFLD Q +  IP  +  E++    K K  +  +    KL+ +S+   L NS                          +P  GV    E+ ++K L+ D+ KWG+++F  A+++ ++PL V+ +TIF++ +L+  F+I   TL+ +L+  E  Y   V YHNN+HAADV QS +VLL+  ALE VF+DLEIL+ IFAS IHD+DHPGV+NQ+L+NTN+ELA +YND+SVLENHHLA+ F LL +E CD    L+K+ RQS+R+M ID+VLATDMSKHM LLADLKTMVETKKV  SG+L LD Y+DRIQ+LQN+VHCADLSNPTKPL +Y++W DR+MEEF+ QGD+ERE  +EISPMCD+  AS+EKSQV FID+IVHPLWETW++LV+PD Q +L+ LE+NR++Y
Sbjct:  200 SMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNL------QDRAPSKRSPMCNQP-SINKATITEEAYQKLASETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKE----KKKRPMSQISGVKKLMHSSS---LTNSC-------------------------IPRFGVKTEQEDVLAKELE-DVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMAIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWY 703

[Close]

BLAST of Phosphodiesterase vs. UniProt/SwissProt
Match: sp|Q9W4S9|PDE4C_DROME (cAMP-specific 3',5'-cyclic phosphodiesterase, isoforms N/G OS=Drosophila melanogaster OX=7227 GN=dnc PE=3 SV=2)

HSP 1 Score: 558.91 bits (1439), Expect = 0.000e+0
Identity = 273/556 (49.10%), Postives = 382/556 (68.71%), Query Frame = 3

Query: 1338 RQNSRFRKPFVATSRRGSLYIFRNADDVIITPFAQILASLRKVRANFMLITNITSNDEKKNKLDSINSPKIEENCSTNNKNITESHEKVAQETLNELEWCLNRLENIQTHRSVSDMASTKFKQIINRELSQFADSSKSGHQISDYICKTFLDSQLDDSIPEASSFERDIDDRKGKGKLESVRRSTKLVKASTEPVLNNSNLVTDSVLNASFVIEAPENDEDSETD--VPLHGVHVANEEEVSKILDSDLKKWGMNLFSFADVTADQPLAVVSYTIFKDLNLINKFQIDSKTLVQFLIKAERSYRNTVPYHNNMHAADVTQSANVLLAGQALENVFSDLEILSVIFASIIHDMDHPGVTNQYLVNTNNELATLYNDNSVLENHHLAMAFSLLAKEECDFLATLSKRHRQSMRRMVIDMVLATDMSKHMTLLADLKTMVETKKVAGSGILTLDTYTDRIQILQNLVHCADLSNPTKPLHIYQKWIDRVMEEFYLQGDKERESELEISPMCDRQTASLEKSQVSFIDFIVHPLWETWSELVYPDTQGMLEALEENRQFY 2999
            R +S F     + SR  S+    + +D+I+TPFAQILASLR VR N + +TN+ ++++ +    S ++ +             E++ ++A +T+ EL+WCL++LE IQTHRSVSDMAS KFK+++N+ELS F++SS+SG+QIS+YIC TFLD Q +  +P   S   + +         + ++S      S  P     + ++         ++ P +  +S T   +P  GV    E E+  +L  +L  WG+ +FS  + + ++PL  V+YTIF+   L+    I  KT + F+   E  Y    P+HN++HAADVTQS NVLL   ALE VF+ LE+   +FA+ IHD+DHPG+TNQ+LVN+++ELA +YND SVLENHHLA+AF LL  + CD    + K+ RQ++R+MVID+VL+TDMSKHM+LLADLKTMVETKKVAGSG+L LD YTDRIQ+L+NLVHCADLSNPTKPL +Y++W+  +MEEF+LQGDKERES ++ISPMCDR  A++EKSQV FID+IVHPLWETW++LV+PD Q +L+ LEENR +Y
Sbjct:  348 RSDSDFEMSPKSMSRNSSIASESHGEDLIVTPFAQILASLRSVRNNLLSLTNVPASNKSRRPNQSSSASRSGNPPGAPLSQGEEAYTRLATDTIEELDWCLDQLETIQTHRSVSDMASLKFKRMLNKELSHFSESSRSGNQISEYICSTFLDKQQEFDLP---SLRVEDNPELVAANAAAGQQSAGQYARSRSPRGPPMSQISG--------VKRPLSHTNSFTGERLPTFGVETPRENELGTLL-GELDTWGIQIFSIGEFSVNRPLTCVAYTIFQSRELLTSLMIPPKTFLNFMSTLEDHYVKDNPFHNSLHAADVTQSTNVLLNTPALEGVFTPLEVGGALFAACIHDVDHPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQNQGCDIFCNMQKKQRQTLRKMVIDIVLSTDMSKHMSLLADLKTMVETKKVAGSGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFLQGDKERESGMDISPMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYY 891

[Close]

BLAST of Phosphodiesterase vs. UniProt/SwissProt
Match: sp|P14646|PDE4B_RAT (cAMP-specific 3',5'-cyclic phosphodiesterase 4B OS=Rattus norvegicus OX=10116 GN=Pde4b PE=1 SV=4)

HSP 1 Score: 558.14 bits (1437), Expect = 0.000e+0
Identity = 285/543 (52.49%), Postives = 385/543 (70.90%), Query Frame = 3

Query: 1371 ATSRRGSLYIFRNADDVIITPFAQILASLRKVRANFMLITNITSNDEKKNKLDSINSPKIEENCSTNNKNITESHEKVAQETLNELEWCLNRLENIQTHRSVSDMASTKFKQIINRELSQFADSSKSGHQISDYICKTFLDSQLDDSIPEASSFERDIDDRKGKGKLESVRRSTKLVKASTEPVLNNSNLVTDSVLNASFVIEAPENDEDSETDVPLHGVHVANEEEVSKILDSDLKKWGMNLFSFADVTADQPLAVVSYTIFKDLNLINKFQIDSKTLVQFLIKAERSYRNTVPYHNNMHAADVTQSANVLLAGQALENVFSDLEILSVIFASIIHDMDHPGVTNQYLVNTNNELATLYNDNSVLENHHLAMAFSLLAKEECDFLATLSKRHRQSMRRMVIDMVLATDMSKHMTLLADLKTMVETKKVAGSGILTLDTYTDRIQILQNLVHCADLSNPTKPLHIYQKWIDRVMEEFYLQGDKERESELEISPMCDRQTASLEKSQVSFIDFIVHPLWETWSELVYPDTQGMLEALEENRQFY 2999
            A SR  SL   ++ DD+I+TPFAQ+LASLR VR NF L+TN+     K+       SP   +   T      ES++K+A ETL EL+WCL++LE IQT+RSVS+MAS KFK+++NREL+  ++ S+SG+Q+S+YI  TFLD Q D  IP  S  ++D + +K +  +  +    KL+ +S+   LNN                         T +   GV+  NE+ ++K L+ DL KWG+N+F+ A  + ++PL  + Y IF++ +L+  F+I S T V +++  E  Y + V YHN++HAADV QS +VLL+  AL+ VF+DLEIL+ IFA+ IHD+DHPGV+NQ+L+NTN+ELA +YND SVLENHHLA+ F LL +E CD    L+K+ RQ++R+MVIDMVLATDMSKHM+LLADLKTMVETKKV  SG+L LD YTDRIQ+L+N+VHCADLSNPTK L +Y++W DR+MEEF+ QGDKERE  +EISPMCD+ TAS+EKSQV FID+IVHPLWETW++LV PD Q +L+ LE+NR +Y
Sbjct:  148 AMSRNSSLPSEQHGDDLIVTPFAQVLASLRIVRNNFTLLTNLHGAPNKR-------SPAASQAPVTRVSLQEESYQKLAMETLEELDWCLDQLETIQTYRSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQNDVEIP--SPTQKDREKKKKQQLMTQISGVKKLMHSSS---LNN-------------------------TSISRFGVNTENEDHLAKELE-DLNKWGLNIFNVAGYSHNRPLTCIMYAIFQERDLLKTFKISSDTFVTYMMTLEDHYHSDVAYHNSLHAADVAQSTHVLLSTPALDAVFTDLEILAAIFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLENHHLAVGFKLLQEEHCDIFQNLTKKQRQTLRKMVIDMVLATDMSKHMSLLADLKTMVETKKVTSSGVLLLDNYTDRIQVLRNMVHCADLSNPTKSLELYRQWTDRIMEEFFQQGDKERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVQPDAQDILDTLEDNRNWY 652

[Close]

BLAST of Phosphodiesterase vs. TrEMBL
Match: A0A1S3KF73 (Phosphodiesterase OS=Lingula unguis OX=7574 GN=LOC106181325 PE=3 SV=1)

HSP 1 Score: 608.986 bits (1569), Expect = 0.000e+0
Identity = 299/551 (54.26%), Postives = 400/551 (72.60%), Query Frame = 3

Query: 1389 SLYIFRNADDVIITPFAQILASLRKVRANFMLITNITSNDEKKNKLDSINSPKIEENCSTNNKNITESHEKVAQETLNELEWCLNRLENIQTHRSVSDMASTKFKQIINRELSQFADSSKSGHQISDYICKTFLDSQLDDSIP-------------EASSFERDIDDRKGK-GKLESVRRSTKLVKASTEPVLNNSNLVTDSVLNASFVIEAPENDEDSETDVPLHGVHVANEEEVSKILDSDLKKWGMNLFSFADVTADQPLAVVSYTIFKDLNLINKFQIDSKTLVQFLIKAERSYRNTVPYHNNMHAADVTQSANVLLAGQALENVFSDLEILSVIFASIIHDMDHPGVTNQYLVNTNNELATLYNDNSVLENHHLAMAFSLLAKEECDFLATLSKRHRQSMRRMVIDMVLATDMSKHMTLLADLKTMVETKKVAGSGILTLDTYTDRIQILQNLVHCADLSNPTKPLHIYQKWIDRVMEEFYLQGDKERESELEISPMCDRQTASLEKSQVSFIDFIVHPLWETWSELVYPDTQGMLEALEENRQFY 2999
            S + FR+ADD+I+TPFAQILASLR VR N++L+TN  ++  ++    S N+    +N +T  K   E+  K++ ETL EL+WCL++LE IQTHRSVSDMAS+KFK+++NRELS FA+SSKSG+QIS+YIC TFLD Q +  +P             +++ + R+I D+K    ++  VR+            L ++N  T                      VP  GV  ANE+ + K+L+ D+ KWG+++F  A+ + ++PL  V YT+F++  L+  FQI  +TL+ +L+  E  YR  VPYHNN+HAADVTQS +VLL+  ALENVF+DLEIL+ IFA  IHD+DHPGVTNQ+L+NT++ELA +YND SVLENHHLA+AF LL +E CD  A L+K+ RQ++RRMVIDMVLATDMSKHM+LLADLKTMVETKKVAGSG+L LD YTDRIQ+LQN+VHC+DLSNPTKPL +Y++W  R+M+EF+ QGD ERE +L+ISPMCD+  A++EKSQV FID+IVHPLWETW++LV+PD Q +L+ LE+NR +Y
Sbjct:   45 SRFSFRHADDLIVTPFAQILASLRSVRNNYILLTNAPTSKTRRGSAHSGNTMNQHQNLNTP-KLSEEAFTKLSVETLEELDWCLDQLETIQTHRSVSDMASSKFKRMLNRELSHFAESSKSGNQISEYICSTFLDKQQEMDLPVMKGDDHHEHNQNQSNKYNREIKDKKTPMSQIMGVRK------------LKHANSFTGG-------------------SVPRFGVECANEDGLGKLLN-DIDKWGVDIFKIAEYSKNRPLTCVVYTVFRERELLKNFQIPPQTLLTYLMHLEDHYRRDVPYHNNVHAADVTQSTHVLLSAPALENVFTDLEILAAIFACAIHDVDHPGVTNQFLINTSSELALMYNDESVLENHHLAVAFKLLTEENCDIFANLNKKQRQTLRRMVIDMVLATDMSKHMSLLADLKTMVETKKVAGSGVLLLDNYTDRIQVLQNMVHCSDLSNPTKPLDLYKQWTTRIMDEFFRQGDIEREKDLDISPMCDKHNATVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNRDWY 562

[Close]

BLAST of Phosphodiesterase vs. TrEMBL
Match: A0A1S3KF58 (Phosphodiesterase OS=Lingula unguis OX=7574 GN=LOC106181325 PE=3 SV=1)

HSP 1 Score: 608.986 bits (1569), Expect = 0.000e+0
Identity = 303/568 (53.35%), Postives = 405/568 (71.30%), Query Frame = 3

Query: 1338 RQNSRFRKPFVATSRRGSLYIFRNADDVIITPFAQILASLRKVRANFMLITNITSNDEKKNKLDSINSPKIEENCSTNNKNITESHEKVAQETLNELEWCLNRLENIQTHRSVSDMASTKFKQIINRELSQFADSSKSGHQISDYICKTFLDSQLDDSIP-------------EASSFERDIDDRKGK-GKLESVRRSTKLVKASTEPVLNNSNLVTDSVLNASFVIEAPENDEDSETDVPLHGVHVANEEEVSKILDSDLKKWGMNLFSFADVTADQPLAVVSYTIFKDLNLINKFQIDSKTLVQFLIKAERSYRNTVPYHNNMHAADVTQSANVLLAGQALENVFSDLEILSVIFASIIHDMDHPGVTNQYLVNTNNELATLYNDNSVLENHHLAMAFSLLAKEECDFLATLSKRHRQSMRRMVIDMVLATDMSKHMTLLADLKTMVETKKVAGSGILTLDTYTDRIQILQNLVHCADLSNPTKPLHIYQKWIDRVMEEFYLQGDKERESELEISPMCDRQTASLEKSQVSFIDFIVHPLWETWSELVYPDTQGMLEALEENRQFY 2999
            R +S F     + SR  SL    +ADD+I+TPFAQILASLR VR N++L+TN  ++  ++    S N+    +N +T  K   E+  K++ ETL EL+WCL++LE IQTHRSVSDMAS+KFK+++NRELS FA+SSKSG+QIS+YIC TFLD Q +  +P             +++ + R+I D+K    ++  VR+            L ++N  T                      VP  GV  ANE+ + K+L+ D+ KWG+++F  A+ + ++PL  V YT+F++  L+  FQI  +TL+ +L+  E  YR  VPYHNN+HAADVTQS +VLL+  ALENVF+DLEIL+ IFA  IHD+DHPGVTNQ+L+NT++ELA +YND SVLENHHLA+AF LL +E CD  A L+K+ RQ++RRMVIDMVLATDMSKHM+LLADLKTMVETKKVAGSG+L LD YTDRIQ+LQN+VHC+DLSNPTKPL +Y++W  R+M+EF+ QGD ERE +L+ISPMCD+  A++EKSQV FID+IVHPLWETW++LV+PD Q +L+ LE+NR +Y
Sbjct:  183 RSDSDFDLSPKSLSRNSSLTSELHADDLIVTPFAQILASLRSVRNNYILLTNAPTSKTRRGSAHSGNTMNQHQNLNTP-KLSEEAFTKLSVETLEELDWCLDQLETIQTHRSVSDMASSKFKRMLNRELSHFAESSKSGNQISEYICSTFLDKQQEMDLPVMKGDDHHEHNQNQSNKYNREIKDKKTPMSQIMGVRK------------LKHANSFTGG-------------------SVPRFGVECANEDGLGKLLN-DIDKWGVDIFKIAEYSKNRPLTCVVYTVFRERELLKNFQIPPQTLLTYLMHLEDHYRRDVPYHNNVHAADVTQSTHVLLSAPALENVFTDLEILAAIFACAIHDVDHPGVTNQFLINTSSELALMYNDESVLENHHLAVAFKLLTEENCDIFANLNKKQRQTLRRMVIDMVLATDMSKHMSLLADLKTMVETKKVAGSGVLLLDNYTDRIQVLQNMVHCSDLSNPTKPLDLYKQWTTRIMDEFFRQGDIEREKDLDISPMCDKHNATVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNRDWY 717

[Close]

BLAST of Phosphodiesterase vs. TrEMBL
Match: A0A1S3KFW4 (Phosphodiesterase OS=Lingula unguis OX=7574 GN=LOC106181325 PE=3 SV=1)

HSP 1 Score: 608.986 bits (1569), Expect = 0.000e+0
Identity = 303/568 (53.35%), Postives = 405/568 (71.30%), Query Frame = 3

Query: 1338 RQNSRFRKPFVATSRRGSLYIFRNADDVIITPFAQILASLRKVRANFMLITNITSNDEKKNKLDSINSPKIEENCSTNNKNITESHEKVAQETLNELEWCLNRLENIQTHRSVSDMASTKFKQIINRELSQFADSSKSGHQISDYICKTFLDSQLDDSIP-------------EASSFERDIDDRKGK-GKLESVRRSTKLVKASTEPVLNNSNLVTDSVLNASFVIEAPENDEDSETDVPLHGVHVANEEEVSKILDSDLKKWGMNLFSFADVTADQPLAVVSYTIFKDLNLINKFQIDSKTLVQFLIKAERSYRNTVPYHNNMHAADVTQSANVLLAGQALENVFSDLEILSVIFASIIHDMDHPGVTNQYLVNTNNELATLYNDNSVLENHHLAMAFSLLAKEECDFLATLSKRHRQSMRRMVIDMVLATDMSKHMTLLADLKTMVETKKVAGSGILTLDTYTDRIQILQNLVHCADLSNPTKPLHIYQKWIDRVMEEFYLQGDKERESELEISPMCDRQTASLEKSQVSFIDFIVHPLWETWSELVYPDTQGMLEALEENRQFY 2999
            R +S F     + SR  SL    +ADD+I+TPFAQILASLR VR N++L+TN  ++  ++    S N+    +N +T  K   E+  K++ ETL EL+WCL++LE IQTHRSVSDMAS+KFK+++NRELS FA+SSKSG+QIS+YIC TFLD Q +  +P             +++ + R+I D+K    ++  VR+            L ++N  T                      VP  GV  ANE+ + K+L+ D+ KWG+++F  A+ + ++PL  V YT+F++  L+  FQI  +TL+ +L+  E  YR  VPYHNN+HAADVTQS +VLL+  ALENVF+DLEIL+ IFA  IHD+DHPGVTNQ+L+NT++ELA +YND SVLENHHLA+AF LL +E CD  A L+K+ RQ++RRMVIDMVLATDMSKHM+LLADLKTMVETKKVAGSG+L LD YTDRIQ+LQN+VHC+DLSNPTKPL +Y++W  R+M+EF+ QGD ERE +L+ISPMCD+  A++EKSQV FID+IVHPLWETW++LV+PD Q +L+ LE+NR +Y
Sbjct:  184 RSDSDFDLSPKSLSRNSSLTSELHADDLIVTPFAQILASLRSVRNNYILLTNAPTSKTRRGSAHSGNTMNQHQNLNTP-KLSEEAFTKLSVETLEELDWCLDQLETIQTHRSVSDMASSKFKRMLNRELSHFAESSKSGNQISEYICSTFLDKQQEMDLPVMKGDDHHEHNQNQSNKYNREIKDKKTPMSQIMGVRK------------LKHANSFTGG-------------------SVPRFGVECANEDGLGKLLN-DIDKWGVDIFKIAEYSKNRPLTCVVYTVFRERELLKNFQIPPQTLLTYLMHLEDHYRRDVPYHNNVHAADVTQSTHVLLSAPALENVFTDLEILAAIFACAIHDVDHPGVTNQFLINTSSELALMYNDESVLENHHLAVAFKLLTEENCDIFANLNKKQRQTLRRMVIDMVLATDMSKHMSLLADLKTMVETKKVAGSGVLLLDNYTDRIQVLQNMVHCSDLSNPTKPLDLYKQWTTRIMDEFFRQGDIEREKDLDISPMCDKHNATVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNRDWY 718

[Close]

BLAST of Phosphodiesterase vs. TrEMBL
Match: A0A1S3KES5 (Phosphodiesterase OS=Lingula unguis OX=7574 GN=LOC106181325 PE=3 SV=1)

HSP 1 Score: 607.446 bits (1565), Expect = 0.000e+0
Identity = 303/568 (53.35%), Postives = 405/568 (71.30%), Query Frame = 3

Query: 1338 RQNSRFRKPFVATSRRGSLYIFRNADDVIITPFAQILASLRKVRANFMLITNITSNDEKKNKLDSINSPKIEENCSTNNKNITESHEKVAQETLNELEWCLNRLENIQTHRSVSDMASTKFKQIINRELSQFADSSKSGHQISDYICKTFLDSQLDDSIP-------------EASSFERDIDDRKGK-GKLESVRRSTKLVKASTEPVLNNSNLVTDSVLNASFVIEAPENDEDSETDVPLHGVHVANEEEVSKILDSDLKKWGMNLFSFADVTADQPLAVVSYTIFKDLNLINKFQIDSKTLVQFLIKAERSYRNTVPYHNNMHAADVTQSANVLLAGQALENVFSDLEILSVIFASIIHDMDHPGVTNQYLVNTNNELATLYNDNSVLENHHLAMAFSLLAKEECDFLATLSKRHRQSMRRMVIDMVLATDMSKHMTLLADLKTMVETKKVAGSGILTLDTYTDRIQILQNLVHCADLSNPTKPLHIYQKWIDRVMEEFYLQGDKERESELEISPMCDRQTASLEKSQVSFIDFIVHPLWETWSELVYPDTQGMLEALEENRQFY 2999
            R +S F     + SR  SL    +ADD+I+TPFAQILASLR VR N++L+TN  ++  ++    S N+    +N +T  K   E+  K++ ETL EL+WCL++LE IQTHRSVSDMAS+KFK+++NRELS FA+SSKSG+QIS+YIC TFLD Q +  +P             +++ + R+I D+K    ++  VR+            L ++N  T                      VP  GV  ANE+ + K+L+ D+ KWG+++F  A+ + ++PL  V YT+F++  L+  FQI  +TL+ +L+  E  YR  VPYHNN+HAADVTQS +VLL+  ALENVF+DLEIL+ IFA  IHD+DHPGVTNQ+L+NT++ELA +YND SVLENHHLA+AF LL +E CD  A L+K+ RQ++RRMVIDMVLATDMSKHM+LLADLKTMVETKKVAGSG+L LD YTDRIQ+LQN+VHC+DLSNPTKPL +Y++W  R+M+EF+ QGD ERE +L+ISPMCD+  A++EKSQV FID+IVHPLWETW++LV+PD Q +L+ LE+NR +Y
Sbjct:   75 RSDSDFDLSPKSLSRNSSLTSELHADDLIVTPFAQILASLRSVRNNYILLTNAPTSKTRRGSAHSGNTMNQHQNLNTP-KLSEEAFTKLSVETLEELDWCLDQLETIQTHRSVSDMASSKFKRMLNRELSHFAESSKSGNQISEYICSTFLDKQQEMDLPVMKGDDHHEHNQNQSNKYNREIKDKKTPMSQIMGVRK------------LKHANSFTGG-------------------SVPRFGVECANEDGLGKLLN-DIDKWGVDIFKIAEYSKNRPLTCVVYTVFRERELLKNFQIPPQTLLTYLMHLEDHYRRDVPYHNNVHAADVTQSTHVLLSAPALENVFTDLEILAAIFACAIHDVDHPGVTNQFLINTSSELALMYNDESVLENHHLAVAFKLLTEENCDIFANLNKKQRQTLRRMVIDMVLATDMSKHMSLLADLKTMVETKKVAGSGVLLLDNYTDRIQVLQNMVHCSDLSNPTKPLDLYKQWTTRIMDEFFRQGDIEREKDLDISPMCDKHNATVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNRDWY 609

[Close]

BLAST of Phosphodiesterase vs. TrEMBL
Match: A0A1S3KF63 (Phosphodiesterase OS=Lingula unguis OX=7574 GN=LOC106181325 PE=3 SV=1)

HSP 1 Score: 607.06 bits (1564), Expect = 0.000e+0
Identity = 303/568 (53.35%), Postives = 405/568 (71.30%), Query Frame = 3

Query: 1338 RQNSRFRKPFVATSRRGSLYIFRNADDVIITPFAQILASLRKVRANFMLITNITSNDEKKNKLDSINSPKIEENCSTNNKNITESHEKVAQETLNELEWCLNRLENIQTHRSVSDMASTKFKQIINRELSQFADSSKSGHQISDYICKTFLDSQLDDSIP-------------EASSFERDIDDRKGK-GKLESVRRSTKLVKASTEPVLNNSNLVTDSVLNASFVIEAPENDEDSETDVPLHGVHVANEEEVSKILDSDLKKWGMNLFSFADVTADQPLAVVSYTIFKDLNLINKFQIDSKTLVQFLIKAERSYRNTVPYHNNMHAADVTQSANVLLAGQALENVFSDLEILSVIFASIIHDMDHPGVTNQYLVNTNNELATLYNDNSVLENHHLAMAFSLLAKEECDFLATLSKRHRQSMRRMVIDMVLATDMSKHMTLLADLKTMVETKKVAGSGILTLDTYTDRIQILQNLVHCADLSNPTKPLHIYQKWIDRVMEEFYLQGDKERESELEISPMCDRQTASLEKSQVSFIDFIVHPLWETWSELVYPDTQGMLEALEENRQFY 2999
            R +S F     + SR  SL    +ADD+I+TPFAQILASLR VR N++L+TN  ++  ++    S N+    +N +T  K   E+  K++ ETL EL+WCL++LE IQTHRSVSDMAS+KFK+++NRELS FA+SSKSG+QIS+YIC TFLD Q +  +P             +++ + R+I D+K    ++  VR+            L ++N  T                      VP  GV  ANE+ + K+L+ D+ KWG+++F  A+ + ++PL  V YT+F++  L+  FQI  +TL+ +L+  E  YR  VPYHNN+HAADVTQS +VLL+  ALENVF+DLEIL+ IFA  IHD+DHPGVTNQ+L+NT++ELA +YND SVLENHHLA+AF LL +E CD  A L+K+ RQ++RRMVIDMVLATDMSKHM+LLADLKTMVETKKVAGSG+L LD YTDRIQ+LQN+VHC+DLSNPTKPL +Y++W  R+M+EF+ QGD ERE +L+ISPMCD+  A++EKSQV FID+IVHPLWETW++LV+PD Q +L+ LE+NR +Y
Sbjct:   80 RSDSDFDLSPKSLSRNSSLTSELHADDLIVTPFAQILASLRSVRNNYILLTNAPTSKTRRGSAHSGNTMNQHQNLNTP-KLSEEAFTKLSVETLEELDWCLDQLETIQTHRSVSDMASSKFKRMLNRELSHFAESSKSGNQISEYICSTFLDKQQEMDLPVMKGDDHHEHNQNQSNKYNREIKDKKTPMSQIMGVRK------------LKHANSFTGG-------------------SVPRFGVECANEDGLGKLLN-DIDKWGVDIFKIAEYSKNRPLTCVVYTVFRERELLKNFQIPPQTLLTYLMHLEDHYRRDVPYHNNVHAADVTQSTHVLLSAPALENVFTDLEILAAIFACAIHDVDHPGVTNQFLINTSSELALMYNDESVLENHHLAVAFKLLTEENCDIFANLNKKQRQTLRRMVIDMVLATDMSKHMSLLADLKTMVETKKVAGSGVLLLDNYTDRIQVLQNMVHCSDLSNPTKPLDLYKQWTTRIMDEFFRQGDIEREKDLDISPMCDKHNATVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNRDWY 614

[Close]

BLAST of Phosphodiesterase vs. Ensembl Cavefish
Match: PDE4D (phosphodiesterase 4D [Source:HGNC Symbol;Acc:HGNC:8783])

HSP 1 Score: 553.518 bits (1425), Expect = 0.000e+0
Identity = 277/551 (50.27%), Postives = 381/551 (69.15%), Query Frame = 3

Query: 1365 FVATSRRGSLYIFRNADDVIITPFAQ------ILASLRKVRANFMLITNITSNDEKKNKLDSINSPKIEENCSTNNKNITESHEKVAQETLNELEWCLNRLENIQTHRSVSDMASTKFKQIINRELSQFADSSKSGHQISDYICKTFLDSQLDDSIPEASSFERDIDDRKGKGKLESVRRSTKLVKASTEPVLNNSNLVTDSVLNASFVIEAPENDEDSETDVPLHGVHVANEEEVSKILDSDLKKWGMNLFSFADVTADQPLAVVSYTIFKDLNLINKFQIDSKTLVQFLIKAERSYRNTVPYHNNMHAADVTQSANVLLAGQALENVFSDLEILSVIFASIIHDMDHPGVTNQYLVNTNNELATLYNDNSVLENHHLAMAFSLLAKEECDFLATLSKRHRQSMRRMVIDMVLATDMSKHMTLLADLKTMVETKKVAGSGILTLDTYTDRIQILQNLVHCADLSNPTKPLHIYQKWIDRVMEEFYLQGDKERESELEISPMCDRQTASLEKSQVSFIDFIVHPLWETWSELVYPDTQGMLEALEENRQFY 2999
            FV + RR S +++R+  D  ++P +       +LASLR VR NF  +TN+   D   NK     SP   +   T      E+++K+A ETL EL+WCL++LE +QT  SVS+MAS KFK+++NREL+  ++ S+SG+Q+S++I  TFLD Q D  +P   + +     +K   ++  V+   KL+ +++   L NSN                         +P  GV    EE ++K L+ D+ KWG+N+F   + + ++PL V+ YTIF++ +L+  F+I   T + +L+  E  Y   V YHNN+HAADVTQS +VLL+  ALE VF+DLEIL+ IFAS IHD+DHPGV+NQ+L+NTN+ELA +YND+SVLENHHLA+ F LL +E CD    L+K+ RQS+R+MVID+VLATDMSKHM LLADLKTMVETKKV  SG+L LD Y+DRIQ+LQN+VHCADLSNPTKPL +Y++W DR+MEEF+ QGD+ERE  +EISPMCD+  AS+EKSQV FID+IVHPLWETW++LV+PD Q +L+ LE+NR++Y
Sbjct:  125 FVHSQRRES-FLYRSDSDYDLSPKSMSRNSSIVLASLRTVRNNFAALTNL-QQDRTSNK----RSPMCNQPTLTKASFTEEAYQKLATETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEFISSTFLDKQHDVEMPTPQTQKEKEKKKKPMSQISGVK---KLMHSTS---LTNSN-------------------------IPRFGVKTETEESLAKELE-DVNKWGLNVFKVTEFSGNRPLTVMMYTIFQERDLLKTFKIPLDTFITYLMTLEDHYHGDVAYHNNIHAADVTQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFSQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWY 637

[Close]

BLAST of Phosphodiesterase vs. Ensembl Cavefish
Match: pde4cb (phosphodiesterase 4C [Source:NCBI gene;Acc:103044346])

HSP 1 Score: 548.125 bits (1411), Expect = 0.000e+0
Identity = 267/532 (50.19%), Postives = 375/532 (70.49%), Query Frame = 3

Query: 1404 RNADDVIITPFAQILASLRKVRANFMLITNITSNDEKKNKLDSINSPKIEENCSTNNKNITESHEKVAQETLNELEWCLNRLENIQTHRSVSDMASTKFKQIINRELSQFADSSKSGHQISDYICKTFLDSQLDDSIPEASSFERDIDDRKGKGKLESVRRSTKLVKASTEPVLNNSNLVTDSVLNASFVIEAPENDEDSETDVPLHGVHVANEEEVSKILDSDLKKWGMNLFSFADVTADQPLAVVSYTIFKDLNLINKFQIDSKTLVQFLIKAERSYRNTVPYHNNMHAADVTQSANVLLAGQALENVFSDLEILSVIFASIIHDMDHPGVTNQYLVNTNNELATLYNDNSVLENHHLAMAFSLLAKEECDFLATLSKRHRQSMRRMVIDMVLATDMSKHMTLLADLKTMVETKKVAGSGILTLDTYTDRIQILQNLVHCADLSNPTKPLHIYQKWIDRVMEEFYLQGDKERESELEISPMCDRQTASLEKSQVSFIDFIVHPLWETWSELVYPDTQGMLEALEENRQFY 2999
            R+ +D+I+TPFAQ+LASLR VR+NF  +T++      K    S N P +   C  +  +  +++ K+A ETL EL+WCL++LE +QT  SVS+MAS KFK+++NREL+Q +++S+SG+Q+S++I  TFL+ Q D  I      E++   R+   ++  V++ T        P L                  AP       T +P  GV   +E  ++K ++ D+ +WG+++F  A+ + ++PL V+ Y+IF++ +L+  F+I + T + F++  E  Y   V YHNN+HAADV QS +VLL+  ALE VF+DLEI++ +FAS IHD+DHPGV+NQ+L+NTN+ELA +YND SVLENHHLA+ F LL +E CD    LSK+ RQS+R+MVIDMVLATDMSKHM  LADLKTMVETKKV   G+L LD Y+DRIQ+LQN+VHCADLSNPTKPL IY++W DR+M E++ QGD+ER+  +EISPMCD+ TAS+EKSQV FID+IVHPLWETW++LV+PD Q +L+ LE+NR++Y
Sbjct:  149 RHGEDMIVTPFAQVLASLRTVRSNFAALTHLQDRGGCKRPTGS-NPPSM---CKPSLPD--DTYPKLAIETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTQLSETSRSGNQVSEFIASTFLEKQHDVEILSPPPKEKE-KKRRPMSQISGVKKLTH------SPSL------------------AP-------TCIPRFGVSTEHESLLAKEVE-DINRWGLDIFKIAEHSGNRPLTVIMYSIFQERDLLKSFKIPTDTFITFMMTLEDHYHADVAYHNNIHAADVVQSTHVLLSSPALEAVFTDLEIMAALFASAIHDVDHPGVSNQFLINTNSELALMYNDASVLENHHLAVGFKLLQEENCDIFQNLSKKQRQSLRKMVIDMVLATDMSKHMNFLADLKTMVETKKVTSLGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLEIYRQWTDRIMVEYFTQGDRERDRGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWY 641

[Close]

Query: 1404 RNADDVIITPFAQILASLRKVRANFMLITNITSNDEKKNKLDSINSPKIEENCSTNNKNITESHEKVAQETLNELEWCLNRLENIQTHRSVSDMASTKFKQIINRELSQFADSSKSGHQISDYICKTFLDSQLDDSIPEASSFERDIDDRKGKGKLESVRRSTKLVKASTEPVLNNSNLVTDSVLNASFVIEAPENDEDSETDVPLHGVHVANEEEVSKILDSDLKKWGMNLFSFADVTADQPLAVVSYTIFKDLNLINKFQIDSKTLVQFLIKAERSYRNTVPYHNNMHAADVTQSANVLLAGQALENVFSDLEILSVIFASIIHDMDHPGVTNQYLVNTNNELATLYNDNSVLENHHLAMAFSLLAKEECDFLATLSKRHRQSMRRMVIDMVLATDMSKHMTLLADLKTMVETKKVAGSGILTLDTYTDRIQILQNLVHCADLSNPTKPLHIYQKWIDRVMEEFYLQGDKERESELEISPMCDRQTASLEKSQVSFIDFIVHPLWETWSELVYPDTQGMLEALEENRQFY 2999
            R+ +D+I+TPFAQ+LASLR VR+NF  +T++      K    S N P +   C  +  +  +++ K+A ETL EL+WCL++LE +QT  SVS+MAS KFK+++NREL+Q +++S+SG+Q+S++I  TFL+ Q D  I      E++   R+   ++  V++ T        P L                  AP       T +P  GV   +E  ++K ++ D+ +WG+++F  A+ + ++PL V+ Y+IF++ +L+  F+I + T + F++  E  Y   V YHNN+HAADV QS +VLL+  ALE VF+DLEI++ +FAS IHD+DHPGV+NQ+L+NTN+ELA +YND SVLENHHLA+ F LL +E CD    LSK+ RQS+R+MVIDMVLATDMSKHM  LADLKTMVETKKV   G+L LD Y+DRIQ+LQN+VHCADLSNPTKPL IY++W DR+M E++ QGD+ER+  +EISPMCD+ TAS+EKSQV FID+IVHPLWETW++LV+PD Q +L+ LE+NR++Y
Sbjct:  155 RHGEDMIVTPFAQVLASLRTVRSNFAALTHLQDRGGCKRPTGS-NPPSM---CKPSLPD--DTYPKLAIETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTQLSETSRSGNQVSEFIASTFLEKQHDVEILSPPPKEKE-KKRRPMSQISGVKKLTH------SPSL------------------AP-------TCIPRFGVSTEHESLLAKEVE-DINRWGLDIFKIAEHSGNRPLTVIMYSIFQERDLLKSFKIPTDTFITFMMTLEDHYHADVAYHNNIHAADVVQSTHVLLSSPALEAVFTDLEIMAALFASAIHDVDHPGVSNQFLINTNSELALMYNDASVLENHHLAVGFKLLQEENCDIFQNLSKKQRQSLRKMVIDMVLATDMSKHMNFLADLKTMVETKKVTSLGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLEIYRQWTDRIMVEYFTQGDRERDRGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWY 647

[Close]

BLAST of Phosphodiesterase vs. Ensembl Cavefish
Match: pde4cb (phosphodiesterase 4C [Source:NCBI gene;Acc:103044346])

HSP 1 Score: 547.74 bits (1410), Expect = 0.000e+0
Identity = 267/532 (50.19%), Postives = 375/532 (70.49%), Query Frame = 3

Query: 1404 RNADDVIITPFAQILASLRKVRANFMLITNITSNDEKKNKLDSINSPKIEENCSTNNKNITESHEKVAQETLNELEWCLNRLENIQTHRSVSDMASTKFKQIINRELSQFADSSKSGHQISDYICKTFLDSQLDDSIPEASSFERDIDDRKGKGKLESVRRSTKLVKASTEPVLNNSNLVTDSVLNASFVIEAPENDEDSETDVPLHGVHVANEEEVSKILDSDLKKWGMNLFSFADVTADQPLAVVSYTIFKDLNLINKFQIDSKTLVQFLIKAERSYRNTVPYHNNMHAADVTQSANVLLAGQALENVFSDLEILSVIFASIIHDMDHPGVTNQYLVNTNNELATLYNDNSVLENHHLAMAFSLLAKEECDFLATLSKRHRQSMRRMVIDMVLATDMSKHMTLLADLKTMVETKKVAGSGILTLDTYTDRIQILQNLVHCADLSNPTKPLHIYQKWIDRVMEEFYLQGDKERESELEISPMCDRQTASLEKSQVSFIDFIVHPLWETWSELVYPDTQGMLEALEENRQFY 2999
            R+ +D+I+TPFAQ+LASLR VR+NF  +T++      K    S N P +   C  +  +  +++ K+A ETL EL+WCL++LE +QT  SVS+MAS KFK+++NREL+Q +++S+SG+Q+S++I  TFL+ Q D  I      E++   R+   ++  V++ T        P L                  AP       T +P  GV   +E  ++K ++ D+ +WG+++F  A+ + ++PL V+ Y+IF++ +L+  F+I + T + F++  E  Y   V YHNN+HAADV QS +VLL+  ALE VF+DLEI++ +FAS IHD+DHPGV+NQ+L+NTN+ELA +YND SVLENHHLA+ F LL +E CD    LSK+ RQS+R+MVIDMVLATDMSKHM  LADLKTMVETKKV   G+L LD Y+DRIQ+LQN+VHCADLSNPTKPL IY++W DR+M E++ QGD+ER+  +EISPMCD+ TAS+EKSQV FID+IVHPLWETW++LV+PD Q +L+ LE+NR++Y
Sbjct:  120 RHGEDMIVTPFAQVLASLRTVRSNFAALTHLQDRGGCKRPTGS-NPPSM---CKPSLPD--DTYPKLAIETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTQLSETSRSGNQVSEFIASTFLEKQHDVEILSPPPKEKE-KKRRPMSQISGVKKLTH------SPSL------------------AP-------TCIPRFGVSTEHESLLAKEVE-DINRWGLDIFKIAEHSGNRPLTVIMYSIFQERDLLKSFKIPTDTFITFMMTLEDHYHADVAYHNNIHAADVVQSTHVLLSSPALEAVFTDLEIMAALFASAIHDVDHPGVSNQFLINTNSELALMYNDASVLENHHLAVGFKLLQEENCDIFQNLSKKQRQSLRKMVIDMVLATDMSKHMNFLADLKTMVETKKVTSLGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLEIYRQWTDRIMVEYFTQGDRERDRGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWY 612

[Close]

BLAST of Phosphodiesterase vs. Ensembl Cavefish
Match: pde4cb (phosphodiesterase 4C [Source:NCBI gene;Acc:103044346])

HSP 1 Score: 547.354 bits (1409), Expect = 0.000e+0
Identity = 267/532 (50.19%), Postives = 375/532 (70.49%), Query Frame = 3

Query: 1404 RNADDVIITPFAQILASLRKVRANFMLITNITSNDEKKNKLDSINSPKIEENCSTNNKNITESHEKVAQETLNELEWCLNRLENIQTHRSVSDMASTKFKQIINRELSQFADSSKSGHQISDYICKTFLDSQLDDSIPEASSFERDIDDRKGKGKLESVRRSTKLVKASTEPVLNNSNLVTDSVLNASFVIEAPENDEDSETDVPLHGVHVANEEEVSKILDSDLKKWGMNLFSFADVTADQPLAVVSYTIFKDLNLINKFQIDSKTLVQFLIKAERSYRNTVPYHNNMHAADVTQSANVLLAGQALENVFSDLEILSVIFASIIHDMDHPGVTNQYLVNTNNELATLYNDNSVLENHHLAMAFSLLAKEECDFLATLSKRHRQSMRRMVIDMVLATDMSKHMTLLADLKTMVETKKVAGSGILTLDTYTDRIQILQNLVHCADLSNPTKPLHIYQKWIDRVMEEFYLQGDKERESELEISPMCDRQTASLEKSQVSFIDFIVHPLWETWSELVYPDTQGMLEALEENRQFY 2999
            R+ +D+I+TPFAQ+LASLR VR+NF  +T++      K    S N P +   C  +  +  +++ K+A ETL EL+WCL++LE +QT  SVS+MAS KFK+++NREL+Q +++S+SG+Q+S++I  TFL+ Q D  I      E++   R+   ++  V++ T        P L                  AP       T +P  GV   +E  ++K ++ D+ +WG+++F  A+ + ++PL V+ Y+IF++ +L+  F+I + T + F++  E  Y   V YHNN+HAADV QS +VLL+  ALE VF+DLEI++ +FAS IHD+DHPGV+NQ+L+NTN+ELA +YND SVLENHHLA+ F LL +E CD    LSK+ RQS+R+MVIDMVLATDMSKHM  LADLKTMVETKKV   G+L LD Y+DRIQ+LQN+VHCADLSNPTKPL IY++W DR+M E++ QGD+ER+  +EISPMCD+ TAS+EKSQV FID+IVHPLWETW++LV+PD Q +L+ LE+NR++Y
Sbjct:  104 RHGEDMIVTPFAQVLASLRTVRSNFAALTHLQDRGGCKRPTGS-NPPSM---CKPSLPD--DTYPKLAIETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTQLSETSRSGNQVSEFIASTFLEKQHDVEILSPPPKEKE-KKRRPMSQISGVKKLTH------SPSL------------------AP-------TCIPRFGVSTEHESLLAKEVE-DINRWGLDIFKIAEHSGNRPLTVIMYSIFQERDLLKSFKIPTDTFITFMMTLEDHYHADVAYHNNIHAADVVQSTHVLLSSPALEAVFTDLEIMAALFASAIHDVDHPGVSNQFLINTNSELALMYNDASVLENHHLAVGFKLLQEENCDIFQNLSKKQRQSLRKMVIDMVLATDMSKHMNFLADLKTMVETKKVTSLGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLEIYRQWTDRIMVEYFTQGDRERDRGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWY 596

[Close]

BLAST of Phosphodiesterase vs. Ensembl Sea Lamprey
Match: pde4ba (phosphodiesterase 4B, cAMP-specific a [Source:ZFIN;Acc:ZDB-GENE-030131-9570])

HSP 1 Score: 317.775 bits (813), Expect = 1.724e-99
Identity = 169/398 (42.46%), Postives = 245/398 (61.56%), Query Frame = 3

Query: 1407 NADDVIITPFAQILASLRKVRANFMLITNITSNDEKKNKLDSINSPKIEENCSTNNKNITESHEKVAQETLNELEWCLNRLENIQTHRSVSDMASTKFKQIINRELSQFADSSKSGHQISDYICKTFLDSQLDDSIPEASSFERDIDDRKGKGKLESVRRSTKLVKASTEPVLNNSNLVTDSVLNASFVIEAPENDEDSETDVPLHGVHVANE-----EEVSKILDSDLKKWGMNLFSFADVTADQPLAVVSYTIFKDLNLINKFQIDSKTLVQFLIKAERSYRNTVPYHNNMHAADVTQSANVLLAGQALENVFSDLEILSVIFASIIHDMDHPGVTNQYLVNTNNELATLYNDNSVLENHHLAMAFSLLAKEECDFLATLSKRHRQSMRRMVIDMV 2585
            + DD+I+TPFAQ+LASLR VR NF  +TN+     ++       SP   +          E ++K+A ET+ EL+WCL++LE +QTHRSVS+MAS KFK+++NRELS  ++ S+SG+Q+S++I  TF+D Q +  +P A             G  E  R+   L        +  +     S L A            S     LHG  +        + +S+ L+ D+ KWG+N+F  A+++ ++PL V+ YTIF++  L+  FQI + T V +++  E  +   V YHN++HAADV QS +VLLA  AL+ VF+DLEIL+ IFAS IHD+DHPGV+NQ+L++TN+ELA +YND SVLENHHLA+ F LL ++ CD    L K+ RQ++R+MVIDMV
Sbjct:    1 HGDDLIVTPFAQVLASLRSVRNNFSALTNLQGTPSRR-------SPAGNQTSYPRAAPSDEGYQKLALETMEELDWCLDQLEAVQTHRSVSEMASNKFKRMLNRELSHLSEMSRSGNQVSEFISSTFMDKQHEMEVPSA-------------GHKEKERQRRPLASGGGVAAVGGAAPAVPSQLAAGV-------SHISGVQRLLHGAAILQRAMIFRDALSQELE-DINKWGINIFRIAELSNNRPLTVLMYTIFQERELLKTFQIPADTFVTYMMTLE-DHHAGVAYHNSLHAADVAQSTHVLLASPALDAVFTDLEILAAIFASAIHDVDHPGVSNQFLISTNSELALMYNDESVLENHHLAVGFKLLQEDNCDIFQNLGKKQRQTLRKMVIDMV 369

[Close]

BLAST of Phosphodiesterase vs. Ensembl Sea Lamprey
Match: ENSPMAT00000007435.1 (pep scaffold:Pmarinus_7.0:GL486982:1709:8825:-1 gene:ENSPMAG00000006710.1 transcript:ENSPMAT00000007435.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 307.375 bits (786), Expect = 6.091e-98
Identity = 139/199 (69.85%), Postives = 170/199 (85.43%), Query Frame = 3

Query: 2331 VFSDLEILSVIFASIIHDMDHPGVTNQYLVNTNNELATLYNDNSVLENHHLAMAFSLLAKEECDFLATLSKRHRQSMRRMVIDMVLATDMSKHMTLLADLKTMVETKKVAGSGILTLDTYTDRIQILQNLVHCADLSNPTKPLHIYQKWIDRVMEEFYLQGDKERESELEISPMCDRQTASLEKSQ-VSFIDFIVHPLW 2924
            VF+DLEIL+ IFAS IHD+DHPGV+NQ+L+NTN+ELA +YND SVLENHHLA+ F LL +E CD    LSK+ RQ++R+MVIDMVLATDMSKHM LLADLKTMVETKKV  SG+L LD YTDRIQ+LQN+VHCADLSNPTKPL +Y++W +R+MEEF+ QGD+ERE  +EISPMCD+ +AS+EKSQ ++ IDF +H  W
Sbjct:    7 VFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDESVLENHHLAVGFKLLQEENCDIFQNLSKKQRQTLRKMVIDMVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYTDRIQVLQNMVHCADLSNPTKPLDVYRQWTERIMEEFFRQGDRERERGMEISPMCDKHSASVEKSQRINAIDFSLHCWW 205

[Close]

BLAST of Phosphodiesterase vs. Ensembl Sea Lamprey
Match: ENSPMAT00000007498.1 (pep scaffold:Pmarinus_7.0:GL486417:1684:4657:1 gene:ENSPMAG00000006774.1 transcript:ENSPMAT00000007498.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 229.95 bits (585), Expect = 3.623e-70
Identity = 102/139 (73.38%), Postives = 120/139 (86.33%), Query Frame = 3

Query: 2583 VLATDMSKHMTLLADLKTMVETKKVAGSGILTLDTYTDRIQILQNLVHCADLSNPTKPLHIYQKWIDRVMEEFYLQGDKERESELEISPMCDRQTASLEKSQVSFIDFIVHPLWETWSELVYPDTQGMLEALEENRQFY 2999
            VLATDMSKHM LL DLKT VETKKV  SG+L LD YTDRIQ+LQN+VHCADLSNPTKPL +Y++W +R+MEEF+ QGD+ERE  ++ISPMCDR +AS+EKSQV FID+IVHPLWETW++LV PD Q ML+ LEENR FY
Sbjct:    2 VLATDMSKHMNLLGDLKTTVETKKVTSSGVLLLDNYTDRIQVLQNMVHCADLSNPTKPLGLYRQWTERIMEEFFQQGDRERERGIDISPMCDRHSASVEKSQVGFIDYIVHPLWETWADLVQPDAQEMLDTLEENRDFY 140

[Close]

BLAST of Phosphodiesterase vs. Ensembl Sea Lamprey
Match: PDE1C (phosphodiesterase 1C [Source:HGNC Symbol;Acc:HGNC:8776])

HSP 1 Score: 210.305 bits (534), Expect = 1.403e-59
Identity = 107/292 (36.64%), Postives = 180/292 (61.64%), Query Frame = 3

Query: 2073 DLKKWGMNLFSFADVTADQPLAVVSYTIFKDLNLINKFQIDSKTLVQFLIKAERSY-RNTVPYHNNMHAADVTQSANVLLAGQALENVFSDLEILSVIFASIIHDMDHPGVTNQYLVNTNNELATLYNDNSVLENHHLAMAFSLLAK-EECDFLATLSKRHRQSMRRMVIDMVLATDMSKHMTLLADLKTMVETKKVAGSGILTLDTYTDRIQILQNLVHCADLSNPTKPLHIYQKWIDRVMEEFYLQGDKERESELEISPMCDRQTASLEKSQVSFIDFIVHPLWETWSEL 2942
            ++ KW  ++F+  + + +  L  + Y +F   +LI +F+I   ++V F+   E  Y ++  PYHN++HAADVTQ+ + L+      +  ++LEILS+IFA+ IHD +H G TN + + T ++ A LYND SVLENHH++ A+ L+ + EE + L  LSK   + +R +V++ VLATDMS H   L  +K +++  +    G+       ++ + +  ++H AD+S+P K  +++++W   +MEEF+ QGDKE E  L  SP+CDR    + +SQ+ FID+IV P +   ++L
Sbjct:  140 EVDKWSFDVFALHEASGEHALKFIVYELFTRYDLIARFKIPVSSVVSFVEALEAGYSKHKNPYHNSVHAADVTQTVHYLMLKTGTIHWLNELEILSMIFAAAIHDYEHTGTTNNFHIQTRSDSAILYNDRSVLENHHVSAAYRLMQEDEEMNILINLSKDDWRELRALVVETVLATDMSCHFHQLKSIKNLLQQPE----GV-------EKPKAMSLMLHTADISHPAKNWNLHRRWTMSLMEEFFRQGDKEAELGLSFSPLCDRNATMVPQSQIGFIDYIVEPTFTVLTDL 420

[Close]

BLAST of Phosphodiesterase vs. Ensembl Sea Lamprey
Match: pde1a (phosphodiesterase 1A, calmodulin-dependent [Source:ZFIN;Acc:ZDB-GENE-090831-2])

HSP 1 Score: 211.46 bits (537), Expect = 3.700e-59
Identity = 103/280 (36.79%), Postives = 169/280 (60.36%), Query Frame = 3

Query: 2082 KWGMNLFSFADVTADQPLAVVSYTIFKDLNLINKFQIDSKTLVQFLIKAERSY-RNTVPYHNNMHAADVTQSANVLLAGQALENVFSDLEILSVIFASIIHDMDHPGVTNQYLVNTNNELATLYNDNSVLENHHLAMAFSLLAKEECDFLATLSKRHRQSMRRMVIDMVLATDMSKHMTLLADLKTMVETKKVAGSGILTLDTYTDRIQILQNLVHCADLSNPTKPLHIYQKWIDRVMEEFYLQGDKERESELEISPMCDRQTASLEKSQVSFIDFIVHP 2918
            KW  ++F   + + +  L  V + +     LI++++I    LV F+   E  Y ++  PYHN  HAADVTQ+ + LL    L +  S+LE L+VIFA+ IHD++H G TN + + T +++A LYND +VLENHH++ A+ L+  ++ +    LSK   + +R +V++MVLATDMS H   +  +K+ ++  +             D+ + +  L+H  D+S+PTK   ++Q+W + +MEEF+ QGD+E +  L  SP+CDR +  + +SQ+ F+DFIV P
Sbjct:  152 KWSFDVFVLNEASGEHALKFVMHELLTRYELISRYKIPVAALVSFVEALEAGYSKHKNPYHNLAHAADVTQTVHYLLLQSGLMHWLSELETLAVIFAAAIHDLEHTGTTNNFHIQTRSDVALLYNDRAVLENHHVSAAYRLMQDDDMNIFINLSKDDWRELRALVVEMVLATDMSCHFQQIKTMKSALQQPE-----------SIDKSKAMSLLLHAGDISHPTKEWPLHQRWTEALMEEFFRQGDREAKLGLPFSPLCDRNSTMVAQSQIGFMDFIVEP 420

[Close]

BLAST of Phosphodiesterase vs. Ensembl Yeast
Match: PDE2 (High-affinity cyclic AMP phosphodiesterase; component of the cAMP-dependent protein kinase signaling system, protects the cell from extracellular cAMP, contains readthrough motif surrounding termination codon [Source:SGD;Acc:S000005887])

HSP 1 Score: 70.8626 bits (172), Expect = 4.698e-13
Identity = 64/222 (28.83%), Postives = 100/222 (45.05%), Query Frame = 3

Query: 2154 IFKDLNLINKFQIDSKTLV------QFLIKAERSYRNTVPYHNNMHAADVTQSANVLLAGQALENVFSDLEILSVIFASIIHDMDHPGVTNQYLVNTNNELATLYNDNSVLENHHLAMAFSLLAKEECDFLATLSKRHRQSMRRMVIDMVLATDMSKHMTLLADLKTMVETKKVAGSGILTLDTYTDRIQILQNLVHCADLSNPTKPLHIYQKWIDRVMEEF 2801
            I+    LI K   D+K L+        L   E SY     +HN  HA DV Q+   L      +N    ++ L +  A+I HD+ HPG  NQ L N  +E+A  + + S+LEN H  + F  L  E    L ++SK+        + + +LATDM+ H        +  E +       L  +    +I ++  ++  AD+SN T+ L I  +W   +  EF
Sbjct:  224 IWCGFTLIKKLSKDAKVLIADNKLLLLLFTLESSYHQVNKFHNFRHAIDVMQATWRLCTYLLKDN---PVQTLLLCMAAIGHDVGHPGTNNQLLCNCESEVAQNFKNVSILENFHREL-FQQLLSEHWPQLLSISKKKFD----FISEAILATDMALH--------SQYEDR-------LMHENPMKQITLISLIIKAADISNVTRTLSISARWAYLITLEF 422

[Close]

BLAST of Phosphodiesterase vs. Ensembl Nematostella
Match: EDO46133 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RQM4])

HSP 1 Score: 511.531 bits (1316), Expect = 8.212e-171
Identity = 265/549 (48.27%), Postives = 362/549 (65.94%), Query Frame = 3

Query: 1362 PFVATSRRGSLYIFRNADDVIITPFAQILASLRKVRANFMLITNITSNDEKKNKLDSINSPKIEENCSTNNKNITESHEKVAQETLNELEWCLNRLENIQTHRSVSDMASTKFKQIINRELSQFADSSKSGHQISDYICKTFLDSQLDDSIPEASSFERDIDDRKGKGKLESVRRSTKLVKASTEPVLNNSNLVTDSVLNASFVIEAPENDEDSETDVPLHGVHVANEEEVSKILDSDLKKWGMNLFSFADVTADQPLAVVSYTIFKDLNLINKFQIDSKTLVQFLIKAERSYRNTVPYHNNMHAADVTQSANVLLAGQALENVFSDLEILSVIFASIIHDMDHPGVTNQYLVNTNNELATLYNDNSVLENHHLAMAFSLLAKEECDFLATLSKRHRQSMRRMVIDMVLATDMSKHMTLLADLKTMVETKKVA--GSGILTLDTYTDRIQILQNLVHCADLSNPTKPLHIYQKWIDRVMEEFYLQGDKERESE-LEISPMCDRQTASLEKSQVSFIDFIVHPLWETWSELVYPDTQGMLEALEENRQFY 2999
            P   TSR  S       ++ ++TPFAQIL+SLR VR  F+ +TN      KK+K       + + +C   +K     +  VA  TL+EL+W L +LE +QTH SVS+MAS KFK+++NREL  F+++++SG+Q+S ++  TF D QL+    ++ + +RD    + +  +  VR+ T+L   S                                  VP  GV V NE E++ IL+ ++ KW  + F+  + T   P+  VSYTI +  +L+  F+I   T + ++   E  Y   VP+HN +HAADVTQ+A+VLL+ QA +NVF+DLEILS I AS +HD+DHPGV N +LV TN+E+A +YND SVLENHHLA+AF LL  E+CD    LSK+ RQ+ RRM+I+MVLATD +KHM+LLA LKTMVETKKVA  GSG+L L+ YTDR+Q+L++LVHCADLSNPTKPL IY+KW+DR+MEEF+ QGDKER+ + +EISPM DR  AS+EKSQV FIDF+  PLWETW ELV PD Q +L+ +E+NRQ+Y
Sbjct:   18 PKCVTSRHHSFSEGTRVEE-LVTPFAQILSSLRNVRNTFVTLTN-----AKKDK-------QFKHSCFCTSKCSHSFYSWVANSTLDELDWVLYQLETLQTHTSVSEMASNKFKRLLNRELKDFSEANQSGNQVSAWVYNTFTDKQLEVETAQSKT-KRDCIRARSRSMVNGVRKLTRLHSFSG--------------------------------SVPRFGVEVQNESELATILE-NVNKWDFDAFALGEATNGHPMLAVSYTILQARDLLKIFKIKPTTFINYMTLVENHYLKDVPFHNCIHAADVTQTAHVLLSAQAFDNVFTDLEILSAIIASAVHDVDHPGVNNHFLVATNSEMALMYNDESVLENHHLAVAFQLLQHEDCDIFENLSKQERQTARRMIIEMVLATDNAKHMSLLASLKTMVETKKVAGTGSGVLCLENYTDRMQVLKSLVHCADLSNPTKPLPIYRKWVDRLMEEFFRQGDKERDIDGMEISPMMDRHNASIEKSQVVFIDFVAQPLWETWGELVQPDAQDLLDTIEDNRQWY 519

[Close]

BLAST of Phosphodiesterase vs. Ensembl Nematostella
Match: EDO37301 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SGA1])

HSP 1 Score: 229.565 bits (584), Expect = 3.939e-67
Identity = 115/289 (39.79%), Postives = 179/289 (61.94%), Query Frame = 3

Query: 2082 KWGMNLFSFADVTADQPLAVVSYTIFKDLNLINKFQIDSKTLVQFLIKAERSY-RNTVPYHNNMHAADVTQSANVLLAGQALENVFSDLEILSVIFASIIHDMDHPGVTNQYLVNTNNELATLYNDNSVLENHHLAMAFSLLAKEECDFLATLSKRHRQSMRRMVIDMVLATDMSKHMTLLADLKTMVETKKVAGSGILTLDTYTDRIQILQNLVHCADLSNPTKPLHIYQKWIDRVMEEFYLQGDKERESELEISPMCDRQTASLEKSQVSFIDFIVHPLWETWSELV 2945
            +W  ++F+ ++     PL  + Y +    +++  F+I + TL +FL   E  Y R++ PYHN+ HAADVT + +  L    +    SDLE+  ++ ++IIHD++H G TN + +N+ ++LA LYND SVLENHH++ AF +L  +E + L+ L+      +R ++ID VLATDMS H   L  +K  +    VAGS I       +  +++Q L+H AD+SNPTK   I+++W  ++MEEF+ QGD E E  L++SP+CDR T  + +SQ+ FIDFIV P  E  SE++
Sbjct:   80 EWTFDVFALSESCEGHPLRYIGYEVLHRRDMLRNFKIHAMTLDRFLQDVETGYKRHSNPYHNDCHAADVTHTVHYFLECMGVSKYLSDLEVFGLLLSAIIHDLEHTGTTNAFHINSRSDLALLYNDRSVLENHHVSCAFRILQDDEKNILSGLNLEQYADVRSLMIDTVLATDMSSHFEQLRLMKVAL----VAGSPI-------ENREVVQLLLHVADISNPTKDWTIHRQWTTKIMEEFFTQGDMEIELGLDVSPLCDRSTTLIPESQIGFIDFIVSPALEVCSEVL 357

[Close]

BLAST of Phosphodiesterase vs. Ensembl Nematostella
Match: EDO32142 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SVX8])

HSP 1 Score: 190.274 bits (482), Expect = 8.762e-50
Identity = 99/304 (32.57%), Postives = 169/304 (55.59%), Query Frame = 3

Query: 2073 DLKKWGMNLFSFADVTADQPLAVVSYTIFKDLNLINKFQIDSKTLVQFLIKAERSYRNTVPYHNNMHAADVTQSANVLLAGQALENVFSDLEILSVIFASIIHDMDHPGVTNQYLVNTNNELATLYNDNSVLENHHLAMAFSLLAKEE-CDFLATLSKRHRQSMRRMVIDMVLATDMSKHMTLLADLKTMVETKKVAG------SGILTLDTYTDRIQILQNLVHCADLSNPTKPLHIYQKWIDRVMEEFYLQGDKERESELE-ISPMCDRQTASLEKSQVSFIDFIVHPLWETWSELVY-PDT 2957
            D   W  ++      +  +PL  +   I     +  K  I    +  +L   E +Y     YHN+ HAADV  +  V LA + ++ V   L+ ++ + A+I+HD+DHPG TN +L N  +ELA LYND +VLE+HH A+AF L A+++  +  + L     +++R+ +IDMV+AT+M++H   L+     +  ++ +       S    L+T  +R  I + L+ CAD++NP +P ++ ++W  R+ EE++ Q D+E+   L  + P+ DR T ++ +SQV FID+ V  L++ W    Y P+T
Sbjct:  519 DEADWDFDILKLEKASNHRPLYFLGLKILNRFRVCEKLNISEDYVKNWLQLIEANYHRKNAYHNSTHAADVLHATAVFLAKERVKAVLEPLDEVASLIAAIVHDVDHPGYTNSFLCNAGSELAILYNDIAVLESHHAALAFKLTARDDKSNIFSNLDVEEFRTVRQAIIDMVMATEMTRHFEHLSKFVNSINKRRSSSTPDSNTSTSTALNTPENRTLIKRMLIKCADIANPARPRYLCKEWAYRIAEEYFSQTDEEKRRGLPVVMPVFDRATCNVPRSQVWFIDYFVSDLYDAWDAFAYVPET 822

[Close]

BLAST of Phosphodiesterase vs. Ensembl Nematostella
Match: EDO43748 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RXZ4])

HSP 1 Score: 176.792 bits (447), Expect = 1.389e-48
Identity = 110/346 (31.79%), Postives = 171/346 (49.42%), Query Frame = 3

Query: 2046 EEVSKILDSDLKKWGMNLFSFADVTADQPLAVVSYTIFKDLNLINKFQIDSKTLVQFLIKAERSYRNTVPYHNNMHAADVTQSANVLLAGQ------------------------------------------------ALENVFSDLEILSVIFASIIHDMDHPGVTNQYLVNTNNELATLYNDNSVLENHHLAMAFSLLAKE-ECDFLATLSKRHRQSMRRMVIDMVLATDMSKHMTLLADLKTMVETKKVAGSGILTLDTYTDRIQILQNLVHCADLSNPTKPLHIYQKWIDRVMEEFYLQGDKERESELEISPMCDRQTASLEKSQVSFIDFIVHPLWETWS 2936
            EE+++++D  +  W   +F   +      L  VSY IF++      F+I  +  + +    E  Y +++PYHN++HA+DV Q    L   +                                                AL +V   LE+LS+  A+ +HD DHPG TN +LV T +  A LYND SVLENHH A AF+LL  + + +FL  LS    +  R + I+ +LATD+ +H  +L+D        K A  G+   D+  DR+  LQ  +  +D+S P+K   I+  W +R++EEFY QGD ER   + +SP  DRQ   + + Q SFI+ +V PL+ +++
Sbjct:   14 EELTRLMDK-VTDWNFPIFDACE--HGNILVQVSYRIFQNAGFFEIFKIPERKFLNYFFALESGY-HSIPYHNSIHASDVLQGVYFLTTAKIPGFCPPGTPQKLGDNESDSDSDSGITSGVLGEGEEDKKDDDGGGDYGALVDVIPLLELLSLYTAAAMHDYDHPGRTNAFLVATLSHQALLYNDRSVLENHHAAAAFTLLMSDPKYNFLCELSPAEFKRFRFLAIEAILATDLKRHFDILSDFNA-----KTAEGGV-NWDSEADRLLTLQFCIKMSDISGPSKRRDIHTLWTERIVEEFYEQGDDERARGMAVSPYMDRQQPHVAQLQDSFINHLVAPLYNSYA 349

[Close]

BLAST of Phosphodiesterase vs. Ensembl Nematostella
Match: EDO32179 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SVS5])

HSP 1 Score: 168.703 bits (426), Expect = 1.579e-44
Identity = 85/263 (32.32%), Postives = 151/263 (57.41%), Query Frame = 3

Query: 2154 IFKDLNLINKFQIDSKTLVQFLIKAERSYRNTVPYHNNMHAADVTQSANVLLAGQALENVFSDLEILSVIFASIIHDMDHPGVTNQYLVNTNNELATLYNDNSVLENHHLAMAFSLLAKEECDFLATLSKRHRQSMRRMVIDMVLATDMSKHMTLLADLKTMVETKKVAGSGILTLDTYTDRIQILQNLVHCADLSNPTKPLHIYQKWIDRVMEEFYLQGDKERESELEISPMCDRQTASLEKSQVSFIDFIVHPLWETWSEL 2942
            ++ DL L+++F+I+   L  FL +  R Y N  P+HN  HA  VTQ    L+    + N  +  ++L ++ +++ HD+DHPG  N Y +N   ELA  YND S LENHH A+AF ++ +++ + L  +S    + +R  +I  +L+TDM++H  +L   K +++      SG    D    +  ++Q ++  +D+SN  +P+ + + W+D +++EF++Q D E+   L ++P  DR   +   +Q+ FI F++ PL+E   EL
Sbjct:  191 MYIDLGLLDEFKIERSKLQHFLFEVYRHY-NPTPFHNFRHAFCVTQMMYGLIWLTEIFNKITKQDLLIMLTSALCHDLDHPGYNNAYQINARTELALRYNDISPLENHHCAVAFDIMKQDKSNILQNVSAETFKKIREGMIKCILSTDMARHSDILNKFKELLK------SG-FKFDDEAHKSMLMQIMIKVSDVSNEARPMDVAEPWLDCLLQEFFIQSDVEKLEGLPVAPFMDRDKVTKPSAQIGFIKFVLVPLFEALGEL 445

[Close]

BLAST of Phosphodiesterase vs. Ensembl Medaka
Match: pde4d (phosphodiesterase 4D [Source:NCBI gene;Acc:101167796])

HSP 1 Score: 561.607 bits (1446), Expect = 0.000e+0
Identity = 274/541 (50.65%), Postives = 376/541 (69.50%), Query Frame = 3

Query: 1377 SRRGSLYIFRNADDVIITPFAQILASLRKVRANFMLITNITSNDEKKNKLDSINSPKIEENCSTNNKNITESHEKVAQETLNELEWCLNRLENIQTHRSVSDMASTKFKQIINRELSQFADSSKSGHQISDYICKTFLDSQLDDSIPEASSFERDIDDRKGKGKLESVRRSTKLVKASTEPVLNNSNLVTDSVLNASFVIEAPENDEDSETDVPLHGVHVANEEEVSKILDSDLKKWGMNLFSFADVTADQPLAVVSYTIFKDLNLINKFQIDSKTLVQFLIKAERSYRNTVPYHNNMHAADVTQSANVLLAGQALENVFSDLEILSVIFASIIHDMDHPGVTNQYLVNTNNELATLYNDNSVLENHHLAMAFSLLAKEECDFLATLSKRHRQSMRRMVIDMVLATDMSKHMTLLADLKTMVETKKVAGSGILTLDTYTDRIQILQNLVHCADLSNPTKPLHIYQKWIDRVMEEFYLQGDKERESELEISPMCDRQTASLEKSQVSFIDFIVHPLWETWSELVYPDTQGMLEALEENRQFY 2999
            SR  S+    + DD+I+TPFAQ+LASLR VR NF  +TN+        +    N P I +   T      E+++K+A ETL EL+WCL++LE +QT  SVS+MAS KFK+++NREL+  ++ S+SG+Q+S++I  TFLD Q +  +P   + +      K   ++  V+   KL  +S+   L NSN                         +P  GV    E+E++K L+  + KWG+N+F   + + ++PL V+ +TIF++ +L+  F+I   T + +L+  E  Y   V YHNN+HAADVTQS +VLL+  ALE VF+DLEIL+ IFAS IHD+DHPGV+NQ+L++TN+ELA +YND+SVLENHHLA+ F LL +E CD    L+K+ RQS+R+MVID+VLATDMSKHM LLADLKTMVETKKV  SG+L LD Y+DRIQ+LQN+VHCADLSNPTKPL +Y++W DR+MEEF+ QGD+ERE  +EISPMCD+  AS+EKSQV FID+I HPLWETW++LV+PD Q +L+ LE+NR++Y
Sbjct:  147 SRNSSIASDIHGDDMIVTPFAQVLASLRTVRNNFGALTNVQQERASTKRSPMCNPPPITKTTFTE-----EAYQKLATETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEFISSTFLDKQHEVEMPTPQTQKEKEKKNKPMSQISGVK---KLQHSSS---LTNSN-------------------------IPRFGVKTETEDELAKELEH-VNKWGLNVFKITEFSGNRPLTVMMHTIFQERDLLKTFKIPLDTFITYLLTLEDHYHGDVAYHNNIHAADVTQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLISTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFSQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIAHPLWETWADLVHPDAQDILDTLEDNREWY 650

[Close]

BLAST of Phosphodiesterase vs. Ensembl Medaka
Match: pde4d (phosphodiesterase 4D [Source:NCBI gene;Acc:101167796])

HSP 1 Score: 560.836 bits (1444), Expect = 0.000e+0
Identity = 274/543 (50.46%), Postives = 377/543 (69.43%), Query Frame = 3

Query: 1371 ATSRRGSLYIFRNADDVIITPFAQILASLRKVRANFMLITNITSNDEKKNKLDSINSPKIEENCSTNNKNITESHEKVAQETLNELEWCLNRLENIQTHRSVSDMASTKFKQIINRELSQFADSSKSGHQISDYICKTFLDSQLDDSIPEASSFERDIDDRKGKGKLESVRRSTKLVKASTEPVLNNSNLVTDSVLNASFVIEAPENDEDSETDVPLHGVHVANEEEVSKILDSDLKKWGMNLFSFADVTADQPLAVVSYTIFKDLNLINKFQIDSKTLVQFLIKAERSYRNTVPYHNNMHAADVTQSANVLLAGQALENVFSDLEILSVIFASIIHDMDHPGVTNQYLVNTNNELATLYNDNSVLENHHLAMAFSLLAKEECDFLATLSKRHRQSMRRMVIDMVLATDMSKHMTLLADLKTMVETKKVAGSGILTLDTYTDRIQILQNLVHCADLSNPTKPLHIYQKWIDRVMEEFYLQGDKERESELEISPMCDRQTASLEKSQVSFIDFIVHPLWETWSELVYPDTQGMLEALEENRQFY 2999
            + SR  S+    + DD+I+TPFAQ+LASLR VR NF  +TN+        +    N P I +   T      E+++K+A ETL EL+WCL++LE +QT  SVS+MAS KFK+++NREL+  ++ S+SG+Q+S++I  TFLD Q +  +P   + +      K   ++  V+   KL  +S+   L NSN                         +P  GV    E+E++K L+  + KWG+N+F   + + ++PL V+ +TIF++ +L+  F+I   T + +L+  E  Y   V YHNN+HAADVTQS +VLL+  ALE VF+DLEIL+ IFAS IHD+DHPGV+NQ+L++TN+ELA +YND+SVLENHHLA+ F LL +E CD    L+K+ RQS+R+MVID+VLATDMSKHM LLADLKTMVETKKV  SG+L LD Y+DRIQ+LQN+VHCADLSNPTKPL +Y++W DR+MEEF+ QGD+ERE  +EISPMCD+  AS+EKSQV FID+I HPLWETW++LV+PD Q +L+ LE+NR++Y
Sbjct:  141 SMSRNSSIASDIHGDDMIVTPFAQVLASLRTVRNNFGALTNVQQERASTKRSPMCNPPPITKTTFTE-----EAYQKLATETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEFISSTFLDKQHEVEMPTPQTQKEKEKKNKPMSQISGVK---KLQHSSS---LTNSN-------------------------IPRFGVKTETEDELAKELEH-VNKWGLNVFKITEFSGNRPLTVMMHTIFQERDLLKTFKIPLDTFITYLLTLEDHYHGDVAYHNNIHAADVTQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLISTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFSQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIAHPLWETWADLVHPDAQDILDTLEDNREWY 646

[Close]

BLAST of Phosphodiesterase vs. Ensembl Medaka
Match: pde4d (phosphodiesterase 4D [Source:NCBI gene;Acc:101167796])

HSP 1 Score: 560.066 bits (1442), Expect = 0.000e+0
Identity = 274/543 (50.46%), Postives = 377/543 (69.43%), Query Frame = 3

Query: 1371 ATSRRGSLYIFRNADDVIITPFAQILASLRKVRANFMLITNITSNDEKKNKLDSINSPKIEENCSTNNKNITESHEKVAQETLNELEWCLNRLENIQTHRSVSDMASTKFKQIINRELSQFADSSKSGHQISDYICKTFLDSQLDDSIPEASSFERDIDDRKGKGKLESVRRSTKLVKASTEPVLNNSNLVTDSVLNASFVIEAPENDEDSETDVPLHGVHVANEEEVSKILDSDLKKWGMNLFSFADVTADQPLAVVSYTIFKDLNLINKFQIDSKTLVQFLIKAERSYRNTVPYHNNMHAADVTQSANVLLAGQALENVFSDLEILSVIFASIIHDMDHPGVTNQYLVNTNNELATLYNDNSVLENHHLAMAFSLLAKEECDFLATLSKRHRQSMRRMVIDMVLATDMSKHMTLLADLKTMVETKKVAGSGILTLDTYTDRIQILQNLVHCADLSNPTKPLHIYQKWIDRVMEEFYLQGDKERESELEISPMCDRQTASLEKSQVSFIDFIVHPLWETWSELVYPDTQGMLEALEENRQFY 2999
            + SR  S+    + DD+I+TPFAQ+LASLR VR NF  +TN+        +    N P I +   T      E+++K+A ETL EL+WCL++LE +QT  SVS+MAS KFK+++NREL+  ++ S+SG+Q+S++I  TFLD Q +  +P   + +      K   ++  V+   KL  +S+   L NSN                         +P  GV    E+E++K L+  + KWG+N+F   + + ++PL V+ +TIF++ +L+  F+I   T + +L+  E  Y   V YHNN+HAADVTQS +VLL+  ALE VF+DLEIL+ IFAS IHD+DHPGV+NQ+L++TN+ELA +YND+SVLENHHLA+ F LL +E CD    L+K+ RQS+R+MVID+VLATDMSKHM LLADLKTMVETKKV  SG+L LD Y+DRIQ+LQN+VHCADLSNPTKPL +Y++W DR+MEEF+ QGD+ERE  +EISPMCD+  AS+EKSQV FID+I HPLWETW++LV+PD Q +L+ LE+NR++Y
Sbjct:   80 SMSRNSSIASDIHGDDMIVTPFAQVLASLRTVRNNFGALTNVQQERASTKRSPMCNPPPITKTTFTE-----EAYQKLATETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEFISSTFLDKQHEVEMPTPQTQKEKEKKNKPMSQISGVK---KLQHSSS---LTNSN-------------------------IPRFGVKTETEDELAKELEH-VNKWGLNVFKITEFSGNRPLTVMMHTIFQERDLLKTFKIPLDTFITYLLTLEDHYHGDVAYHNNIHAADVTQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLISTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFSQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIAHPLWETWADLVHPDAQDILDTLEDNREWY 585

[Close]

BLAST of Phosphodiesterase vs. Ensembl Medaka
Match: pde4d (phosphodiesterase 4D [Source:NCBI gene;Acc:101167796])

HSP 1 Score: 560.066 bits (1442), Expect = 0.000e+0
Identity = 274/541 (50.65%), Postives = 376/541 (69.50%), Query Frame = 3

Query: 1377 SRRGSLYIFRNADDVIITPFAQILASLRKVRANFMLITNITSNDEKKNKLDSINSPKIEENCSTNNKNITESHEKVAQETLNELEWCLNRLENIQTHRSVSDMASTKFKQIINRELSQFADSSKSGHQISDYICKTFLDSQLDDSIPEASSFERDIDDRKGKGKLESVRRSTKLVKASTEPVLNNSNLVTDSVLNASFVIEAPENDEDSETDVPLHGVHVANEEEVSKILDSDLKKWGMNLFSFADVTADQPLAVVSYTIFKDLNLINKFQIDSKTLVQFLIKAERSYRNTVPYHNNMHAADVTQSANVLLAGQALENVFSDLEILSVIFASIIHDMDHPGVTNQYLVNTNNELATLYNDNSVLENHHLAMAFSLLAKEECDFLATLSKRHRQSMRRMVIDMVLATDMSKHMTLLADLKTMVETKKVAGSGILTLDTYTDRIQILQNLVHCADLSNPTKPLHIYQKWIDRVMEEFYLQGDKERESELEISPMCDRQTASLEKSQVSFIDFIVHPLWETWSELVYPDTQGMLEALEENRQFY 2999
            SR  S+    + DD+I+TPFAQ+LASLR VR NF  +TN+        +    N P I +   T      E+++K+A ETL EL+WCL++LE +QT  SVS+MAS KFK+++NREL+  ++ S+SG+Q+S++I  TFLD Q +  +P   + +      K   ++  V+   KL  +S+   L NSN                         +P  GV    E+E++K L+  + KWG+N+F   + + ++PL V+ +TIF++ +L+  F+I   T + +L+  E  Y   V YHNN+HAADVTQS +VLL+  ALE VF+DLEIL+ IFAS IHD+DHPGV+NQ+L++TN+ELA +YND+SVLENHHLA+ F LL +E CD    L+K+ RQS+R+MVID+VLATDMSKHM LLADLKTMVETKKV  SG+L LD Y+DRIQ+LQN+VHCADLSNPTKPL +Y++W DR+MEEF+ QGD+ERE  +EISPMCD+  AS+EKSQV FID+I HPLWETW++LV+PD Q +L+ LE+NR++Y
Sbjct:  155 SRNSSIASDIHGDDMIVTPFAQVLASLRTVRNNFGALTNVQQERASTKRSPMCNPPPITKTTFTE-----EAYQKLATETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEFISSTFLDKQHEVEMPTPQTQKEKEKKNKPMSQISGVK---KLQHSSS---LTNSN-------------------------IPRFGVKTETEDELAKELEH-VNKWGLNVFKITEFSGNRPLTVMMHTIFQERDLLKTFKIPLDTFITYLLTLEDHYHGDVAYHNNIHAADVTQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLISTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFSQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIAHPLWETWADLVHPDAQDILDTLEDNREWY 658

[Close]

BLAST of Phosphodiesterase vs. Ensembl Medaka
Match: pde4d (phosphodiesterase 4D [Source:NCBI gene;Acc:101167796])

HSP 1 Score: 559.296 bits (1440), Expect = 0.000e+0
Identity = 274/543 (50.46%), Postives = 377/543 (69.43%), Query Frame = 3

Query: 1371 ATSRRGSLYIFRNADDVIITPFAQILASLRKVRANFMLITNITSNDEKKNKLDSINSPKIEENCSTNNKNITESHEKVAQETLNELEWCLNRLENIQTHRSVSDMASTKFKQIINRELSQFADSSKSGHQISDYICKTFLDSQLDDSIPEASSFERDIDDRKGKGKLESVRRSTKLVKASTEPVLNNSNLVTDSVLNASFVIEAPENDEDSETDVPLHGVHVANEEEVSKILDSDLKKWGMNLFSFADVTADQPLAVVSYTIFKDLNLINKFQIDSKTLVQFLIKAERSYRNTVPYHNNMHAADVTQSANVLLAGQALENVFSDLEILSVIFASIIHDMDHPGVTNQYLVNTNNELATLYNDNSVLENHHLAMAFSLLAKEECDFLATLSKRHRQSMRRMVIDMVLATDMSKHMTLLADLKTMVETKKVAGSGILTLDTYTDRIQILQNLVHCADLSNPTKPLHIYQKWIDRVMEEFYLQGDKERESELEISPMCDRQTASLEKSQVSFIDFIVHPLWETWSELVYPDTQGMLEALEENRQFY 2999
            + SR  S+    + DD+I+TPFAQ+LASLR VR NF  +TN+        +    N P I +   T      E+++K+A ETL EL+WCL++LE +QT  SVS+MAS KFK+++NREL+  ++ S+SG+Q+S++I  TFLD Q +  +P   + +      K   ++  V+   KL  +S+   L NSN                         +P  GV    E+E++K L+  + KWG+N+F   + + ++PL V+ +TIF++ +L+  F+I   T + +L+  E  Y   V YHNN+HAADVTQS +VLL+  ALE VF+DLEIL+ IFAS IHD+DHPGV+NQ+L++TN+ELA +YND+SVLENHHLA+ F LL +E CD    L+K+ RQS+R+MVID+VLATDMSKHM LLADLKTMVETKKV  SG+L LD Y+DRIQ+LQN+VHCADLSNPTKPL +Y++W DR+MEEF+ QGD+ERE  +EISPMCD+  AS+EKSQV FID+I HPLWETW++LV+PD Q +L+ LE+NR++Y
Sbjct:   83 SMSRNSSIASDIHGDDMIVTPFAQVLASLRTVRNNFGALTNVQQERASTKRSPMCNPPPITKTTFTE-----EAYQKLATETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEFISSTFLDKQHEVEMPTPQTQKEKEKKNKPMSQISGVK---KLQHSSS---LTNSN-------------------------IPRFGVKTETEDELAKELEH-VNKWGLNVFKITEFSGNRPLTVMMHTIFQERDLLKTFKIPLDTFITYLLTLEDHYHGDVAYHNNIHAADVTQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLISTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFSQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIAHPLWETWADLVHPDAQDILDTLEDNREWY 588

[Close]

BLAST of Phosphodiesterase vs. Planmine SMEST
Match: SMESG000077093.1 (SMESG000077093.1)

HSP 1 Score: 1438.71 bits (3723), Expect = 0.000e+0
Identity = 695/697 (99.71%), Postives = 696/697 (99.86%), Query Frame = 3

Query:  948 MRMSLCCLKLRLNQTKSNSSRRKTNNDSNGVVEDRTPVHNGNTDENNSPKSPPHATPERDSFDLSIKEEPIVVLRSEPTRQNVHTNGNICSDDESKLTESRNSSFVKSVFHKSIRFDDENMDYNSSFSVKRQNSRFRKPFVATSRRGSLYIFRNADDVIITPFAQILASLRKVRANFMLITNITSNDEKKNKLDSINSPKIEENCSTNNKNITESHEKVAQETLNELEWCLNRLENIQTHRSVSDMASTKFKQIINRELSQFADSSKSGHQISDYICKTFLDSQLDDSIPEASSFERDIDDRKGKGKLESVRRSTKLVKASTEPVLNNSNLVTDSVLNASFVIEAPENDEDSETDVPLHGVHVANEEEVSKILDSDLKKWGMNLFSFADVTADQPLAVVSYTIFKDLNLINKFQIDSKTLVQFLIKAERSYRNTVPYHNNMHAADVTQSANVLLAGQALENVFSDLEILSVIFASIIHDMDHPGVTNQYLVNTNNELATLYNDNSVLENHHLAMAFSLLAKEECDFLATLSKRHRQSMRRMVIDMVLATDMSKHMTLLADLKTMVETKKVAGSGILTLDTYTDRIQILQNLVHCADLSNPTKPLHIYQKWIDRVMEEFYLQGDKERESELEISPMCDRQTASLEKSQVSFIDFIVHPLWETWSELVYPDTQGMLEALEENRQFYFNKSQEKSKTINE 3038
            MRMSLCCLKLRLNQTKSNSSRRKTNNDSNG+VEDRTPVHNGNTDENNSPKSPPHATPERDSFDLSIKEEPIVVLRSEPTRQNVHTNGNICSDDESKLTESRNSSFVKSVFHKSIRFDDENMDYNSSFSVKRQNSRFRKPFVATSRRGSLYIFRNADDVIITPFAQILASLRKVRANFMLITNITSNDEKKNKLDSINSPKIEENCSTNNKNITESHEKVAQETLNELEWCLNRLENIQTHRSVSDMASTKFKQIINRELSQFADSSKSGHQISDYICKTFLDSQLDDSIPEASSFERDIDDRKGKGK ESVRRSTKLVKASTEPVLNNSNLVTDSVLNASFVIEAPENDEDSETDVPLHGVHVANEEEVSKILDSDLKKWGMNLFSFADVTADQPLAVVSYTIFKDLNLINKFQIDSKTLVQFLIKAERSYRNTVPYHNNMHAADVTQSANVLLAGQALENVFSDLEILSVIFASIIHDMDHPGVTNQYLVNTNNELATLYNDNSVLENHHLAMAFSLLAKEECDFLATLSKRHRQSMRRMVIDMVLATDMSKHMTLLADLKTMVETKKVAGSGILTLDTYTDRIQILQNLVHCADLSNPTKPLHIYQKWIDRVMEEFYLQGDKERESELEISPMCDRQTASLEKSQVSFIDFIVHPLWETWSELVYPDTQGMLEALEENRQFYFNKSQEKSKTINE
Sbjct:    1 MRMSLCCLKLRLNQTKSNSSRRKTNNDSNGMVEDRTPVHNGNTDENNSPKSPPHATPERDSFDLSIKEEPIVVLRSEPTRQNVHTNGNICSDDESKLTESRNSSFVKSVFHKSIRFDDENMDYNSSFSVKRQNSRFRKPFVATSRRGSLYIFRNADDVIITPFAQILASLRKVRANFMLITNITSNDEKKNKLDSINSPKIEENCSTNNKNITESHEKVAQETLNELEWCLNRLENIQTHRSVSDMASTKFKQIINRELSQFADSSKSGHQISDYICKTFLDSQLDDSIPEASSFERDIDDRKGKGKFESVRRSTKLVKASTEPVLNNSNLVTDSVLNASFVIEAPENDEDSETDVPLHGVHVANEEEVSKILDSDLKKWGMNLFSFADVTADQPLAVVSYTIFKDLNLINKFQIDSKTLVQFLIKAERSYRNTVPYHNNMHAADVTQSANVLLAGQALENVFSDLEILSVIFASIIHDMDHPGVTNQYLVNTNNELATLYNDNSVLENHHLAMAFSLLAKEECDFLATLSKRHRQSMRRMVIDMVLATDMSKHMTLLADLKTMVETKKVAGSGILTLDTYTDRIQILQNLVHCADLSNPTKPLHIYQKWIDRVMEEFYLQGDKERESELEISPMCDRQTASLEKSQVSFIDFIVHPLWETWSELVYPDTQGMLEALEENRQFYFNKSQEKSKTINE 697

[Close]

BLAST of Phosphodiesterase vs. Planmine SMEST
Match: SMESG000077093.1 (SMESG000077093.1)

HSP 1 Score: 1434.85 bits (3713), Expect = 0.000e+0
Identity = 693/695 (99.71%), Postives = 694/695 (99.86%), Query Frame = 3

Query:  954 MSLCCLKLRLNQTKSNSSRRKTNNDSNGVVEDRTPVHNGNTDENNSPKSPPHATPERDSFDLSIKEEPIVVLRSEPTRQNVHTNGNICSDDESKLTESRNSSFVKSVFHKSIRFDDENMDYNSSFSVKRQNSRFRKPFVATSRRGSLYIFRNADDVIITPFAQILASLRKVRANFMLITNITSNDEKKNKLDSINSPKIEENCSTNNKNITESHEKVAQETLNELEWCLNRLENIQTHRSVSDMASTKFKQIINRELSQFADSSKSGHQISDYICKTFLDSQLDDSIPEASSFERDIDDRKGKGKLESVRRSTKLVKASTEPVLNNSNLVTDSVLNASFVIEAPENDEDSETDVPLHGVHVANEEEVSKILDSDLKKWGMNLFSFADVTADQPLAVVSYTIFKDLNLINKFQIDSKTLVQFLIKAERSYRNTVPYHNNMHAADVTQSANVLLAGQALENVFSDLEILSVIFASIIHDMDHPGVTNQYLVNTNNELATLYNDNSVLENHHLAMAFSLLAKEECDFLATLSKRHRQSMRRMVIDMVLATDMSKHMTLLADLKTMVETKKVAGSGILTLDTYTDRIQILQNLVHCADLSNPTKPLHIYQKWIDRVMEEFYLQGDKERESELEISPMCDRQTASLEKSQVSFIDFIVHPLWETWSELVYPDTQGMLEALEENRQFYFNKSQEKSKTINE 3038
            MSLCCLKLRLNQTKSNSSRRKTNNDSNG+VEDRTPVHNGNTDENNSPKSPPHATPERDSFDLSIKEEPIVVLRSEPTRQNVHTNGNICSDDESKLTESRNSSFVKSVFHKSIRFDDENMDYNSSFSVKRQNSRFRKPFVATSRRGSLYIFRNADDVIITPFAQILASLRKVRANFMLITNITSNDEKKNKLDSINSPKIEENCSTNNKNITESHEKVAQETLNELEWCLNRLENIQTHRSVSDMASTKFKQIINRELSQFADSSKSGHQISDYICKTFLDSQLDDSIPEASSFERDIDDRKGKGK ESVRRSTKLVKASTEPVLNNSNLVTDSVLNASFVIEAPENDEDSETDVPLHGVHVANEEEVSKILDSDLKKWGMNLFSFADVTADQPLAVVSYTIFKDLNLINKFQIDSKTLVQFLIKAERSYRNTVPYHNNMHAADVTQSANVLLAGQALENVFSDLEILSVIFASIIHDMDHPGVTNQYLVNTNNELATLYNDNSVLENHHLAMAFSLLAKEECDFLATLSKRHRQSMRRMVIDMVLATDMSKHMTLLADLKTMVETKKVAGSGILTLDTYTDRIQILQNLVHCADLSNPTKPLHIYQKWIDRVMEEFYLQGDKERESELEISPMCDRQTASLEKSQVSFIDFIVHPLWETWSELVYPDTQGMLEALEENRQFYFNKSQEKSKTINE
Sbjct:    1 MSLCCLKLRLNQTKSNSSRRKTNNDSNGMVEDRTPVHNGNTDENNSPKSPPHATPERDSFDLSIKEEPIVVLRSEPTRQNVHTNGNICSDDESKLTESRNSSFVKSVFHKSIRFDDENMDYNSSFSVKRQNSRFRKPFVATSRRGSLYIFRNADDVIITPFAQILASLRKVRANFMLITNITSNDEKKNKLDSINSPKIEENCSTNNKNITESHEKVAQETLNELEWCLNRLENIQTHRSVSDMASTKFKQIINRELSQFADSSKSGHQISDYICKTFLDSQLDDSIPEASSFERDIDDRKGKGKFESVRRSTKLVKASTEPVLNNSNLVTDSVLNASFVIEAPENDEDSETDVPLHGVHVANEEEVSKILDSDLKKWGMNLFSFADVTADQPLAVVSYTIFKDLNLINKFQIDSKTLVQFLIKAERSYRNTVPYHNNMHAADVTQSANVLLAGQALENVFSDLEILSVIFASIIHDMDHPGVTNQYLVNTNNELATLYNDNSVLENHHLAMAFSLLAKEECDFLATLSKRHRQSMRRMVIDMVLATDMSKHMTLLADLKTMVETKKVAGSGILTLDTYTDRIQILQNLVHCADLSNPTKPLHIYQKWIDRVMEEFYLQGDKERESELEISPMCDRQTASLEKSQVSFIDFIVHPLWETWSELVYPDTQGMLEALEENRQFYFNKSQEKSKTINE 695

[Close]

BLAST of Phosphodiesterase vs. Planmine SMEST
Match: SMESG000077093.1 (SMESG000077093.1)

HSP 1 Score: 1123.61 bits (2905), Expect = 0.000e+0
Identity = 545/551 (98.91%), Postives = 545/551 (98.91%), Query Frame = 3

Query: 1386 GSLYIFRNADDVIITPFAQILASLRKVRANFMLITNITSNDEKKNKLDSINSPKIEENCSTNNKNITESHEKVAQETLNELEWCLNRLENIQTHRSVSDMASTKFKQIINRELSQFADSSKSGHQISDYICKTFLDSQLDDSIPEASSFERDIDDRKGKGKLESVRRSTKLVKASTEPVLNNSNLVTDSVLNASFVIEAPENDEDSETDVPLHGVHVANEEEVSKILDSDLKKWGMNLFSFADVTADQPLAVVSYTIFKDLNLINKFQIDSKTLVQFLIKAERSYRNTVPYHNNMHAADVTQSANVLLAGQALENVFSDLEILSVIFASIIHDMDHPGVTNQYLVNTNNELATLYNDNSVLENHHLAMAFSLLAKEECDFLATLSKRHRQSMRRMVIDMVLATDMSKHMTLLADLKTMVETKKVAGSGILTLDTYTDRIQILQNLVHCADLSNPTKPLHIYQKWIDRVMEEFYLQGDKERESELEISPMCDRQTASLEKSQVSFIDFIVHPLWETWSELVYPDTQGMLEALEENRQFYFNKSQEKSKTINE 3038
            G L    NADDVIITPFAQILASLRKVRANFMLITNITSNDEKKNKLDSINSPKIEENCSTNNKNITESHEKVAQETLNELEWCLNRLENIQTHRSVSDMASTKFKQIINRELSQFADSSKSGHQISDYICKTFLDSQLDDSIPEASSFERDIDDRKGKGK ESVRRSTKLVKASTEPVLNNSNLVTDSVLNASFVIEAPENDEDSETDVPLHGVHVANEEEVSKILDSDLKKWGMNLFSFADVTADQPLAVVSYTIFKDLNLINKFQIDSKTLVQFLIKAERSYRNTVPYHNNMHAADVTQSANVLLAGQALENVFSDLEILSVIFASIIHDMDHPGVTNQYLVNTNNELATLYNDNSVLENHHLAMAFSLLAKEECDFLATLSKRHRQSMRRMVIDMVLATDMSKHMTLLADLKTMVETKKVAGSGILTLDTYTDRIQILQNLVHCADLSNPTKPLHIYQKWIDRVMEEFYLQGDKERESELEISPMCDRQTASLEKSQVSFIDFIVHPLWETWSELVYPDTQGMLEALEENRQFYFNKSQEKSKTINE
Sbjct:  119 GYLSEIGNADDVIITPFAQILASLRKVRANFMLITNITSNDEKKNKLDSINSPKIEENCSTNNKNITESHEKVAQETLNELEWCLNRLENIQTHRSVSDMASTKFKQIINRELSQFADSSKSGHQISDYICKTFLDSQLDDSIPEASSFERDIDDRKGKGKFESVRRSTKLVKASTEPVLNNSNLVTDSVLNASFVIEAPENDEDSETDVPLHGVHVANEEEVSKILDSDLKKWGMNLFSFADVTADQPLAVVSYTIFKDLNLINKFQIDSKTLVQFLIKAERSYRNTVPYHNNMHAADVTQSANVLLAGQALENVFSDLEILSVIFASIIHDMDHPGVTNQYLVNTNNELATLYNDNSVLENHHLAMAFSLLAKEECDFLATLSKRHRQSMRRMVIDMVLATDMSKHMTLLADLKTMVETKKVAGSGILTLDTYTDRIQILQNLVHCADLSNPTKPLHIYQKWIDRVMEEFYLQGDKERESELEISPMCDRQTASLEKSQVSFIDFIVHPLWETWSELVYPDTQGMLEALEENRQFYFNKSQEKSKTINE 669

[Close]

BLAST of Phosphodiesterase vs. Planmine SMEST
Match: SMESG000032148.1 (SMESG000032148.1)

HSP 1 Score: 635.565 bits (1638), Expect = 0.000e+0
Identity = 308/552 (55.80%), Postives = 403/552 (73.01%), Query Frame = 3

Query: 1368 VATSRRGSLYIFRNADDVIITPFAQILASLRKVRANFMLITNITSNDEKKNKLDSINSPKIEENCSTNNKNITESHEKVAQETLNELEWCLNRLENIQTHRSVSDMASTKFKQIINRELSQFADSSKSGHQISDYICKTFLDSQLDDSIPEASSFERDIDDRKGKGKLE-----SVRRSTKLVKASTEPVLNNSNLVTDSVLNASFVIEAPENDEDSETDVPLHGVHVANEEEVSKILDSDLKKWGMNLFSFADVTADQPLAVVSYTIFKDLNLINKFQIDSKTLVQFLIKAERSYRNTVPYHNNMHAADVTQSANVLLAGQALENVFSDLEILSVIFASIIHDMDHPGVTNQYLVNTNNELATLYNDNSVLENHHLAMAFSLLAKEECDFLATLSKRHRQSMRRMVIDMVLATDMSKHMTLLADLKTMVETKKVAGSGILTLDTYTDRIQILQNLVHCADLSNPTKPLHIYQKWIDRVMEEFYLQGDKERESELEISPMCDRQTASLEKSQVSFIDFIVHPLWETWSELVYPDTQGMLEALEENRQFYFNK 3008
            VA SRRGSLYIFR++DD+I+TPFAQILASLR VRANF+LITN+ S+ E +    SI++               +S   +  ETL ELEWCL RLE++QTHRSVSDMAS+KFK+I+N+ELSQ+AD SKSG+QISDYIC TFLD+  D+S+ + S +E     R+G  + E         S +    +   + N    +    ++   +    EN       V   G++     E+++I+++ L  WGM++F  + ++ + PL V+S+ +F+   L  KF I S   + F+ + E  Y   VPYHN+ HAADVTQS NVLL   +LENVFSDLEI++VIFA IIHD+DHPGVTNQYL+NTN++LA +YND SVLENHHL++AF++L+   CD +  L+K+ RQS R+MVIDMVLATDMSKHM+LLADLKTMVETKKVAGSGIL LD Y DRIQILQN+VHCADLSNPTKPL++Y+ W +++M+EF+ QGDKERE  LEISPMCDR+TA++EKSQVSFIDFIVHPLWETWS+LVYP+ Q +L+ LE+NR++YF++
Sbjct:  140 VAASRRGSLYIFRHSDDLIVTPFAQILASLRNVRANFILITNVQSSREAR--FGSISASSHTLRSEDLKIEGDDSQRSLTMETLEELEWCLERLESMQTHRSVSDMASSKFKKILNKELSQYADQSKSGNQISDYICTTFLDADGDNSLDQTSEYEDTDPPRRGSSREELDEHSETDESERYADGAPSLISNEHQKIHKQTISFKPIFVDIEN-------VSTFGINSTRNVEMTEIIETTLDTWGMDIFLVSTLSDNNPLTVISFALFRKYKLFEKFSIQSSIFLSFITEIENKYHKDVPYHNSTHAADVTQSTNVLLGALSLENVFSDLEIMAVIFACIIHDVDHPGVTNQYLINTNDQLALMYNDASVLENHHLSVAFTVLSLPNCDIITNLTKKQRQSFRKMVIDMVLATDMSKHMSLLADLKTMVETKKVAGSGILNLDNYNDRIQILQNMVHCADLSNPTKPLNLYRSWTEKIMQEFFRQGDKEREKNLEISPMCDRETATVEKSQVSFIDFIVHPLWETWSDLVYPEAQDILDTLEKNREWYFSQ 682

[Close]

BLAST of Phosphodiesterase vs. Planmine SMEST
Match: SMESG000032148.1 (SMESG000032148.1)

HSP 1 Score: 613.609 bits (1581), Expect = 0.000e+0
Identity = 298/546 (54.58%), Postives = 394/546 (72.16%), Query Frame = 3

Query: 1386 GSLYIFRNADDVIITPFAQILASLRKVRANFMLITNITSNDEKKNKLDSINSPKIEENCSTNNKNITESHEKVAQETLNELEWCLNRLENIQTHRSVSDMASTKFKQIINRELSQFADSSKSGHQISDYICKTFLDSQLDDSIPEASSFERDIDDRKGKGKLE-----SVRRSTKLVKASTEPVLNNSNLVTDSVLNASFVIEAPENDEDSETDVPLHGVHVANEEEVSKILDSDLKKWGMNLFSFADVTADQPLAVVSYTIFKDLNLINKFQIDSKTLVQFLIKAERSYRNTVPYHNNMHAADVTQSANVLLAGQALENVFSDLEILSVIFASIIHDMDHPGVTNQYLVNTNNELATLYNDNSVLENHHLAMAFSLLAKEECDFLATLSKRHRQSMRRMVIDMVLATDMSKHMTLLADLKTMVETKKVAGSGILTLDTYTDRIQILQNLVHCADLSNPTKPLHIYQKWIDRVMEEFYLQGDKERESELEISPMCDRQTASLEKSQVSFIDFIVHPLWETWSELVYPDTQGMLEALEENRQFYFNK 3008
            G  + F ++DD+I+TPFAQILASLR VRANF+LITN+ S+ E +    SI++               +S   +  ETL ELEWCL RLE++QTHRSVSDMAS+KFK+I+N+ELSQ+AD SKSG+QISDYIC TFLD+  D+S+ + S +E     R+G  + E         S +    +   + N    +    ++   +    EN       V   G++     E+++I+++ L  WGM++F  + ++ + PL V+S+ +F+   L  KF I S   + F+ + E  Y   VPYHN+ HAADVTQS NVLL   +LENVFSDLEI++VIFA IIHD+DHPGVTNQYL+NTN++LA +YND SVLENHHL++AF++L+   CD +  L+K+ RQS R+MVIDMVLATDMSKHM+LLADLKTMVETKKVAGSGIL LD Y DRIQILQN+VHCADLSNPTKPL++Y+ W +++M+EF+ QGDKERE  LEISPMCDR+TA++EKSQVSFIDFIVHPLWETWS+LVYP+ Q +L+ LE+NR++YF++
Sbjct:   64 GEPHAFAHSDDLIVTPFAQILASLRNVRANFILITNVQSSREAR--FGSISASSHTLRSEDLKIEGDDSQRSLTMETLEELEWCLERLESMQTHRSVSDMASSKFKKILNKELSQYADQSKSGNQISDYICTTFLDADGDNSLDQTSEYEDTDPPRRGSSREELDEHSETDESERYADGAPSLISNEHQKIHKQTISFKPIFVDIEN-------VSTFGINSTRNVEMTEIIETTLDTWGMDIFLVSTLSDNNPLTVISFALFRKYKLFEKFSIQSSIFLSFITEIENKYHKDVPYHNSTHAADVTQSTNVLLGALSLENVFSDLEIMAVIFACIIHDVDHPGVTNQYLINTNDQLALMYNDASVLENHHLSVAFTVLSLPNCDIITNLTKKQRQSFRKMVIDMVLATDMSKHMSLLADLKTMVETKKVAGSGILNLDNYNDRIQILQNMVHCADLSNPTKPLNLYRSWTEKIMQEFFRQGDKEREKNLEISPMCDRETATVEKSQVSFIDFIVHPLWETWSDLVYPEAQDILDTLEKNREWYFSQ 600

The following BLAST results are available for this feature:

BLAST of Phosphodiesterase vs. Ensembl Human
BLAST of Phosphodiesterase vs. Ensembl Celegans
BLAST of Phosphodiesterase vs. Ensembl Fly
BLAST of Phosphodiesterase vs. Ensembl Zebrafish
BLAST of Phosphodiesterase vs. Ensembl Xenopus
BLAST of Phosphodiesterase vs. Ensembl Mouse
BLAST of Phosphodiesterase vs. UniProt/SwissProt
BLAST of Phosphodiesterase vs. TrEMBL
BLAST of Phosphodiesterase vs. Ensembl Cavefish
BLAST of Phosphodiesterase vs. Ensembl Sea Lamprey
BLAST of Phosphodiesterase vs. Ensembl Yeast
BLAST of Phosphodiesterase vs. Ensembl Nematostella
BLAST of Phosphodiesterase vs. Ensembl Medaka
BLAST of Phosphodiesterase vs. Planmine SMEST

BLAST of Phosphodiesterase vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
PDE4D	0.000e+0	51.47	phosphodiesterase 4D [Source:HGNC Symbol;Acc:HGNC:...	[more]
PDE4D	0.000e+0	51.47	phosphodiesterase 4D [Source:HGNC Symbol;Acc:HGNC:...	[more]
PDE4D	0.000e+0	51.47	phosphodiesterase 4D [Source:HGNC Symbol;Acc:HGNC:...	[more]
PDE4D	0.000e+0	51.47	phosphodiesterase 4D [Source:HGNC Symbol;Acc:HGNC:...	[more]
PDE4D	0.000e+0	51.66	phosphodiesterase 4D [Source:HGNC Symbol;Acc:HGNC:...	[more]

BLAST of Phosphodiesterase vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5


Match Name	E-value	Identity	Description
pde-4	1.736e-175	48.45	Probable 3',5'-cyclic phosphodiesterase pde-4 [So...	[more]
pde-4	9.657e-174	48.61	Probable 3',5'-cyclic phosphodiesterase pde-4 [So...	[more]
pde-4	1.668e-173	48.61	Probable 3',5'-cyclic phosphodiesterase pde-4 [So...	[more]
pde-4	3.161e-173	48.61	Probable 3',5'-cyclic phosphodiesterase pde-4 [So...	[more]
pde-4	3.755e-173	48.61	Probable 3',5'-cyclic phosphodiesterase pde-4 [So...	[more]

BLAST of Phosphodiesterase vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5


Match Name	E-value	Identity	Description
dnc	0.000e+0	49.10	gene:FBgn0000479 transcript:FBtr0070512	[more]
dnc	0.000e+0	48.51	gene:FBgn0000479 transcript:FBtr0070515	[more]
dnc	0.000e+0	49.01	gene:FBgn0000479 transcript:FBtr0070520	[more]
dnc	0.000e+0	49.10	gene:FBgn0000479 transcript:FBtr0070519	[more]
dnc	0.000e+0	48.33	gene:FBgn0000479 transcript:FBtr0070513	[more]

BLAST of Phosphodiesterase vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
pde4d	0.000e+0	51.75	phosphodiesterase 4D, cAMP-specific [Source:ZFIN;A...	[more]
pde4d	0.000e+0	51.75	phosphodiesterase 4D, cAMP-specific [Source:ZFIN;A...	[more]
BX510928.2	0.000e+0	51.75	phosphodiesterase 4D, cAMP-specific [Source:NCBI g...	[more]
pde4cb	0.000e+0	47.99	phosphodiesterase 4C, cAMP-specific b [Source:ZFIN...	[more]
pde4ca	0.000e+0	49.28	phosphodiesterase 4C, cAMP-specific a [Source:ZFIN...	[more]

BLAST of Phosphodiesterase vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5


Match Name	E-value	Identity	Description
PDE4D	0.000e+0	51.52	phosphodiesterase 4D [Source:NCBI gene;Acc:1004964...	[more]
PDE4D	0.000e+0	51.26	phosphodiesterase 4D [Source:NCBI gene;Acc:1004964...	[more]
PDE4D	0.000e+0	51.26	phosphodiesterase 4D [Source:NCBI gene;Acc:1004964...	[more]
PDE4D	0.000e+0	51.26	phosphodiesterase 4D [Source:NCBI gene;Acc:1004964...	[more]
PDE4D	0.000e+0	51.26	phosphodiesterase 4D [Source:NCBI gene;Acc:1004964...	[more]

BLAST of Phosphodiesterase vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Pde4d	0.000e+0	51.65	phosphodiesterase 4D, cAMP specific [Source:MGI Sy...	[more]
Pde4d	0.000e+0	51.65	phosphodiesterase 4D, cAMP specific [Source:MGI Sy...	[more]
Pde4d	0.000e+0	51.65	phosphodiesterase 4D, cAMP specific [Source:MGI Sy...	[more]
Pde4d	0.000e+0	51.65	phosphodiesterase 4D, cAMP specific [Source:MGI Sy...	[more]
Pde4d	0.000e+0	51.65	phosphodiesterase 4D, cAMP specific [Source:MGI Sy...	[more]

BLAST of Phosphodiesterase vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|Q01063\|PDE4D_MOUSE	0.000e+0	51.65	cAMP-specific 3',5'-cyclic phosphodiesterase 4D OS...	[more]
sp\|Q08499\|PDE4D_HUMAN	0.000e+0	51.66	cAMP-specific 3',5'-cyclic phosphodiesterase 4D OS...	[more]
sp\|P14270\|PDE4D_RAT	0.000e+0	51.47	cAMP-specific 3',5'-cyclic phosphodiesterase 4D OS...	[more]
sp\|Q9W4S9\|PDE4C_DROME	0.000e+0	49.10	cAMP-specific 3',5'-cyclic phosphodiesterase, isof...	[more]
sp\|P14646\|PDE4B_RAT	0.000e+0	52.49	cAMP-specific 3',5'-cyclic phosphodiesterase 4B OS...	[more]

BLAST of Phosphodiesterase vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
A0A1S3KF73	0.000e+0	54.26	Phosphodiesterase OS=Lingula unguis OX=7574 GN=LOC...	[more]
A0A1S3KF58	0.000e+0	53.35	Phosphodiesterase OS=Lingula unguis OX=7574 GN=LOC...	[more]
A0A1S3KFW4	0.000e+0	53.35	Phosphodiesterase OS=Lingula unguis OX=7574 GN=LOC...	[more]
A0A1S3KES5	0.000e+0	53.35	Phosphodiesterase OS=Lingula unguis OX=7574 GN=LOC...	[more]
A0A1S3KF63	0.000e+0	53.35	Phosphodiesterase OS=Lingula unguis OX=7574 GN=LOC...	[more]

BLAST of Phosphodiesterase vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
PDE4D	0.000e+0	50.27	phosphodiesterase 4D [Source:HGNC Symbol;Acc:HGNC:...	[more]
pde4cb	0.000e+0	50.19	phosphodiesterase 4C [Source:NCBI gene;Acc:1030443...	[more]
pde4cb	0.000e+0	50.19	phosphodiesterase 4C [Source:NCBI gene;Acc:1030443...	[more]
pde4cb	0.000e+0	50.19	phosphodiesterase 4C [Source:NCBI gene;Acc:1030443...	[more]
pde4cb	0.000e+0	50.19	phosphodiesterase 4C [Source:NCBI gene;Acc:1030443...	[more]

BLAST of Phosphodiesterase vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5


Match Name	E-value	Identity	Description
pde4ba	1.724e-99	42.46	phosphodiesterase 4B, cAMP-specific a [Source:ZFIN...	[more]
ENSPMAT00000007435.1	6.091e-98	69.85	pep scaffold:Pmarinus_7.0:GL486982:1709:8825:-1 ge...	[more]
ENSPMAT00000007498.1	3.623e-70	73.38	pep scaffold:Pmarinus_7.0:GL486417:1684:4657:1 gen...	[more]
PDE1C	1.403e-59	36.64	phosphodiesterase 1C [Source:HGNC Symbol;Acc:HGNC:...	[more]
pde1a	3.700e-59	36.79	phosphodiesterase 1A, calmodulin-dependent [Source...	[more]

BLAST of Phosphodiesterase vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 1


Match Name	E-value	Identity	Description
PDE2	4.698e-13	28.83	High-affinity cyclic AMP phosphodiesterase; compon...	[more]

BLAST of Phosphodiesterase vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5


Match Name	E-value	Identity	Description
EDO46133	8.212e-171	48.27	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO37301	3.939e-67	39.79	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO32142	8.762e-50	32.57	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO43748	1.389e-48	31.79	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO32179	1.579e-44	32.32	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of Phosphodiesterase vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5


Match Name	E-value	Identity	Description
pde4d	0.000e+0	50.65	phosphodiesterase 4D [Source:NCBI gene;Acc:1011677...	[more]
pde4d	0.000e+0	50.46	phosphodiesterase 4D [Source:NCBI gene;Acc:1011677...	[more]
pde4d	0.000e+0	50.46	phosphodiesterase 4D [Source:NCBI gene;Acc:1011677...	[more]
pde4d	0.000e+0	50.65	phosphodiesterase 4D [Source:NCBI gene;Acc:1011677...	[more]
pde4d	0.000e+0	50.46	phosphodiesterase 4D [Source:NCBI gene;Acc:1011677...	[more]

BLAST of Phosphodiesterase vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5


Match Name	E-value	Identity	Description
SMESG000077093.1	0.000e+0	99.71	SMESG000077093.1	[more]
SMESG000077093.1	0.000e+0	99.71	SMESG000077093.1	[more]
SMESG000077093.1	0.000e+0	98.91	SMESG000077093.1	[more]
SMESG000032148.1	0.000e+0	55.80	SMESG000032148.1	[more]
SMESG000032148.1	0.000e+0	54.58	SMESG000032148.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30028562 ID=SMED30028562|Name=Phosphodiesterase|organism=Schmidtea mediterranea sexual|type=transcript|length=3232bp
TGACATCTTACATATAAATGCGATGATGCTGTATTTTTCTATAAAACTAA
ATTGTCTACAAATAATTTTCGAGGCTGGATCATATACAGATCACAATACA
AAAATCGGTAATTAACTCTCTTCATGTTGTTACTAATTTAATGATCTCTA
AATGACTTAAACTAATGAAATATTAATTATAAAATAACTTATGTAATTTT
TAATCGTAAAACTGGTCAGACTACACTTGCTAAAATTCCACTTTCACTTC
CATTGCGAGGCCCACATTCTGAAAATCTCCACCAGCATAACCACTCAGGC
ACTTTGCTCTTTTCCTATTGGTTAATTTCGTTACACTGAAAACTAATAAT
TACATTAATATTTCTATTTAATAAAAATTAAAATGATTGATTGCAACAAT
TTTGCACTGATAACTTGGCAAAAAAATTTATATTATAATCAGTCTCCCTT
TATTTCCAATGGGTTATAATTAATACAAAATAGAGATATCAAAAAGTTTA
TGAATGGAATATTGAATATCTTAATTTCGGTGAAAAACTCATGTTGAAAT
CGCGGTCTACATGTCAAATTAAGATAAATACATTTCGAAATTCTGAAATT
CCTTTGACAAATGGTTTTCAGCAATCAACAGCACACACACAAACACGCAC
ACACGCGCACACTCATGGAAACATACAGACACACACACACATAGACATGT
ACAATCAGAGTTAAGCACACATGTCATTGTCGAGCTGTGAGTGAAAGGAA
GAGAGAAAATCAAATGAACATGCAATCCGGCTTGTATAAGTAATGCACAC
TTTGTGTGTCAACTACATGTTAGAAAGTGCAACTTCATTATGATTTGATA
GTTTTAATCTAATGGGAAATGTTAGCTTGATTTTCTAGAAATATATAGTT
GCATTTGAGGCCATTTCAATTGTGTTAGCTGTGGAACTAATTGAGTTATG
AGAATGTCTCTCTGTTGCTTGAAATTGCGATTGAATCAAACAAAATCAAA
TTCGAGTAGGAGAAAAACAAACAACGACAGCAATGGAGTAGTTGAAGATC
GGACACCGGTACACAATGGAAACACCGATGAAAACAATTCACCGAAATCT
CCGCCTCATGCAACACCGGAACGAGACTCATTTGATCTCTCAATTAAAGA
AGAGCCAATAGTAGTTCTAAGATCAGAACCAACTCGTCAGAATGTCCACA
CAAACGGAAACATCTGTTCGGATGACGAGAGTAAATTAACCGAATCTCGC
AATAGTAGTTTCGTGAAATCGGTTTTTCACAAAAGTATTCGATTCGATGA
CGAGAACATGGATTACAATTCCAGTTTCTCTGTAAAGCGCCAAAATTCCC
GTTTTCGAAAACCATTCGTTGCGACTTCTAGACGAGGTTCATTGTATATT
TTTAGGAACGCTGATGATGTGATTATTACACCGTTCGCGCAAATTCTCGC
AAGCCTGAGAAAAGTTCGCGCTAATTTCATGTTGATTACAAATATCACCA
GTAACGATGAAAAAAAAAACAAATTGGACTCAATCAACTCTCCGAAAATT
GAAGAAAATTGCTCAACAAACAATAAAAATATAACTGAATCTCATGAAAA
GGTAGCCCAGGAAACTCTCAATGAGCTAGAATGGTGTTTGAATAGACTGG
AAAATATTCAGACTCATAGATCTGTCAGCGACATGGCATCAACAAAATTT
AAACAAATAATTAATCGAGAACTCAGTCAATTTGCAGACAGTTCAAAATC
AGGCCATCAAATTTCTGATTATATCTGTAAAACGTTTCTCGATTCTCAGT
TGGATGATTCAATACCCGAGGCGTCGTCATTTGAGCGTGACATTGATGAC
AGAAAAGGAAAAGGAAAACTCGAATCTGTCAGACGGAGTACCAAATTAGT
GAAAGCAAGCACAGAACCAGTTTTGAATAATTCTAATCTAGTCACTGATT
CGGTATTGAATGCGTCGTTTGTTATTGAAGCTCCAGAAAATGACGAAGAC
TCAGAAACGGACGTACCTTTGCACGGTGTTCATGTTGCAAATGAGGAAGA
GGTTTCAAAGATTCTTGATAGTGATCTAAAGAAGTGGGGGATGAATTTAT
TCAGTTTTGCCGATGTTACAGCCGATCAACCTCTAGCAGTAGTTTCTTAT
ACTATTTTTAAAGATTTAAACTTAATCAATAAATTTCAAATTGATTCAAA
AACTCTAGTGCAATTTCTCATCAAAGCAGAAAGAAGTTACCGTAATACAG
TACCCTATCATAATAATATGCATGCTGCCGACGTTACGCAATCTGCTAAT
GTTTTATTGGCTGGTCAGGCCTTAGAAAATGTTTTCTCGGATCTCGAGAT
CCTCTCAGTGATATTTGCTAGCATCATTCACGACATGGATCATCCGGGCG
TCACTAACCAATACTTAGTCAACACAAATAACGAATTGGCAACTCTTTAC
AATGATAATTCTGTGTTGGAAAATCACCACTTAGCAATGGCATTTTCATT
GTTGGCTAAGGAGGAATGCGATTTTCTCGCTACGCTTAGTAAAAGGCACC
GGCAATCCATGCGACGAATGGTTATTGATATGGTTCTAGCCACAGACATG
TCTAAGCATATGACACTTCTTGCCGATCTCAAAACGATGGTGGAAACAAA
GAAAGTCGCCGGCTCTGGAATATTGACATTAGACACTTACACGGACCGGA
TACAGATCTTGCAAAATCTTGTACATTGCGCTGATCTGAGTAATCCAACC
AAACCATTACATATTTATCAGAAATGGATAGATAGGGTTATGGAGGAGTT
CTATCTTCAAGGTGACAAAGAACGTGAAAGTGAGCTAGAAATTAGTCCAA
TGTGTGACAGACAAACTGCATCTTTAGAAAAATCACAGGTGAGCTTCATA
GATTTCATTGTCCATCCACTTTGGGAGACTTGGTCAGAACTTGTTTATCC
TGATACTCAAGGAATGCTTGAAGCTCTTGAAGAAAACAGACAATTCTATT
TTAACAAATCCCAAGAAAAATCCAAAACCATAAATGAATGATTTTGATCT
ATCCTTTATGTTGAGATGAATTATTGAGAAATTGTTTTATTTATGAATTT
GAGAAAATGAATAACTATTTTAAAAATTAATATTTTTTTCAGTGTTGAAC
ATAGCGCTGTAAATAAGTAGGTTATGTCTTTCTTGTCATGTTTAATTTGA
CAGTATTATTAACAAAATAACAAATATTCAAC

protein sequence of SMED30028562-orf-1

>SMED30028562-orf-1 ID=SMED30028562-orf-1|Name=SMED30028562-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=698bp
MRMSLCCLKLRLNQTKSNSSRRKTNNDSNGVVEDRTPVHNGNTDENNSPK
SPPHATPERDSFDLSIKEEPIVVLRSEPTRQNVHTNGNICSDDESKLTES
RNSSFVKSVFHKSIRFDDENMDYNSSFSVKRQNSRFRKPFVATSRRGSLY
IFRNADDVIITPFAQILASLRKVRANFMLITNITSNDEKKNKLDSINSPK
IEENCSTNNKNITESHEKVAQETLNELEWCLNRLENIQTHRSVSDMASTK
FKQIINRELSQFADSSKSGHQISDYICKTFLDSQLDDSIPEASSFERDID
DRKGKGKLESVRRSTKLVKASTEPVLNNSNLVTDSVLNASFVIEAPENDE
DSETDVPLHGVHVANEEEVSKILDSDLKKWGMNLFSFADVTADQPLAVVS
YTIFKDLNLINKFQIDSKTLVQFLIKAERSYRNTVPYHNNMHAADVTQSA
NVLLAGQALENVFSDLEILSVIFASIIHDMDHPGVTNQYLVNTNNELATL
YNDNSVLENHHLAMAFSLLAKEECDFLATLSKRHRQSMRRMVIDMVLATD
MSKHMTLLADLKTMVETKKVAGSGILTLDTYTDRIQILQNLVHCADLSNP
TKPLHIYQKWIDRVMEEFYLQGDKERESELEISPMCDRQTASLEKSQVSF
IDFIVHPLWETWSELVYPDTQGMLEALEENRQFYFNKSQEKSKTINE*

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000099	neuron
PLANA:0000101	muscle cell
PLANA:0003117	parapharyngeal cell

Vocabulary: **INTERPRO**
Term	Definition
IPR040844	PDE4_UCR
IPR036971	PDEase_catalytic_dom_sf
IPR023088	PDEase
IPR003607	HD/PDEase_dom
IPR002073	PDEase_catalytic_dom
IPR023174	PDEase_CS

Vocabulary: **molecular function**
Term	Definition
GO:0008081	phosphoric diester hydrolase activity
GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity
GO:0016787	hydrolase activity
GO:0046872	metal ion binding

Vocabulary: **biological process**
Term	Definition
GO:0007165	signal transduction

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
None	No IPR available	COILS	Coil	Coil	coord: 696..697
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 11..54
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 11..62
None	No IPR available	PANTHER	PTHR11347	CYCLIC NUCLEOTIDE PHOSPHODIESTERASE	coord: 142..686
None	No IPR available	PANTHER	PTHR11347:SF74	CAMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE 4A	coord: 142..686
None	No IPR available	SUPERFAMILY	SSF109604	HD-domain/PDEase-like	coord: 371..691
IPR023088	3'5'-cyclic nucleotide phosphodiesterase	PRINTS	PR00387	PDIESTERASE1	coord: 609..625 score: 52.24 coord: 478..493 score: 53.12 coord: 433..446 score: 54.29 coord: 464..477 score: 44.29 coord: 505..521 score: 53.53 coord: 592..605 score: 56.0
IPR003607	HD/PDEase domain	SMART	SM00471	hd_13	coord: 435..610 e-value: 0.0035 score: 26.6
IPR003607	HD/PDEase domain	CDD	cd00077	HDc	coord: 437..619 e-value: 1.97605E-10 score: 57.3493
IPR040844	Phosphodiesterase 4 upstream conserved regions (UCR)	PFAM	PF18100	PDE4_UCR	coord: 160..282 e-value: 1.1E-46 score: 158.3
IPR002073	3'5'-cyclic nucleotide phosphodiesterase, catalytic domain	PFAM	PF00233	PDEase_I	coord: 437..677 e-value: 1.0E-87 score: 293.8
IPR002073	3'5'-cyclic nucleotide phosphodiesterase, catalytic domain	PROSITE	PS51845	PDEASE_I_2	coord: 346..691 score: 131.222
IPR036971	3'5'-cyclic nucleotide phosphodiesterase, catalytic domain superfamily	GENE3D	G3DSA:1.10.1300.10		coord: 367..697 e-value: 3.9E-133 score: 445.8
IPR023174	3'5'-cyclic nucleotide phosphodiesterase, conserved site	PROSITE	PS00126	PDEASE_I_1	coord: 478..489