Serine/threonine kinase 32A
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30028559 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 5
Homology
BLAST of Serine/threonine kinase 32A vs. Ensembl Human
Match: STK32B (serine/threonine kinase 32B [Source:HGNC Symbol;Acc:HGNC:14217]) HSP 1 Score: 301.597 bits (771), Expect = 2.275e-97 Identity = 185/402 (46.02%), Postives = 249/402 (61.94%), Query Frame = 1
Query: 151 NCEISFSDFEVLRAIXXXX-----XXXXXXXXXXXXXXXXNKVACIEKHAVSNVMREIRILLKLNHPFIVNLWYTFQDSNCQSMART*LFIIHLFQNESTINRQFVSHIGVKRTLDNEDLFVVVDLLTGGDMRFHSNNQTLKFSEKTVKLYICEISLVLDYLQSKRIIHRDIKPDNLLLDENGHIHLTDFNVATELQ-SNKSYSICGTKPYMAYEFFSDSL-CNTGYSYEVDWWSLGIVAFELLVKKRPFKIQSNSSMNECRQIIENSKFYSHRYSDFISGEMLDLIFSLLRLESEYRVSSLKQIQENLLMKDINWNQVAKKQIEPDFKPSSNHLNCDPTFELEEMIIESKPLHKKEKRLAKQLKNNKNQ----MNSXXXXXXXXXXXXFTVFNRESFLKKE 1323
N E++F F++LRAIGKG +K+ KKM+AMKYMNK CIE+ V NV RE++I+ L HPF+VNLWY+FQD ED+F+VVDLL GGD+R+H Q + F+E TVKLYICE++L L+YLQ IIHRDIKPDN+LLDE+GH+H+TDFN+AT ++ + ++ S+ GTKPYMA E F + GYSY VDWWSLGI A+ELL RP++I S + ++E + + + + YS M+ L+ LL + E RVSSL IQ + D+NW+ V KK + P F P+ LNCDPTFELEEMI+ESKPLHKK+KRLAK + + +N L+ LE + +EF +FNRE +++
Sbjct: 15 NEEVNFDHFQILRAIGKGSFGKVCIVQKRDTKKMYAMKYMNKQKCIERDEVRNVFRELQIMQGLEHPFLVNLWYSFQDE--------------------------------------EDMFMVVDLLLGGDLRYHLQ-QNVHFTEGTVKLYICELALALEYLQRYHIIHRDIKPDNILLDEHGHVHITDFNIATVVKGAERASSMAGTKPYMAPEVFQVYMDRGPGYSYPVDWWSLGITAYELLRGWRPYEIHSVTPIDEILNMFKVERVH---YSSTWCKGMVALLRKLLTKDPESRVSSLHDIQSVPYLADMNWDAVFKKALMPGFVPNKGRLNCDPTFELEEMILESKPLHKKKKRLAKNRSRDGTKDSCPLNGHLQHCLETVREEFIIFNREKLRRQQ 374
BLAST of Serine/threonine kinase 32A vs. Ensembl Human
Match: STK32B (serine/threonine kinase 32B [Source:HGNC Symbol;Acc:HGNC:14217]) HSP 1 Score: 297.745 bits (761), Expect = 1.659e-96 Identity = 165/362 (45.58%), Postives = 222/362 (61.33%), Query Frame = 1
Query: 256 NKVACIEKHAVSNVMREIRILLKLNHPFIVNLWYTFQDSNCQSMART*LFIIHLFQNESTINRQFVSHIGVKRTLDNEDLFVVVDLLTGGDMRFHSNNQTLKFSEKTVKLYICEISLVLDYLQSKRIIHRDIKPDNLLLDENGHIHLTDFNVATELQ-SNKSYSICGTKPYMAYEFFSDSL-CNTGYSYEVDWWSLGIVAFELLVKKRPFKIQSNSSMNECRQIIENSKFYSHRYSDFISGEMLDLIFSLLRLESEYRVSSLKQIQENLLMKDINWNQVAKKQIEPDFKPSSNHLNCDPTFELEEMIIESKPLHKKEKRLAKQLKNNKNQ----MNSXXXXXXXXXXXXFTVFNRESFLKKE 1323
NK CIE+ V NV RE++I+ L HPF+VNLWY+FQD ED+F+VVDLL GGD+R+H Q + F+E TVKLYICE++L L+YLQ IIHRDIKPDN+LLDE+GH+H+TDFN+AT ++ + ++ S+ GTKPYMA E F + GYSY VDWWSLGI A+ELL RP++I S + ++E + + + + YS M+ L+ LL + E RVSSL IQ + D+NW+ V KK + P F P+ LNCDPTFELEEMI+ESKPLHKK+KRLAK + + +N L+ LE + +EF +FNRE +++
Sbjct: 8 NKQKCIERDEVRNVFRELQIMQGLEHPFLVNLWYSFQDE--------------------------------------EDMFMVVDLLLGGDLRYHLQ-QNVHFTEGTVKLYICELALALEYLQRYHIIHRDIKPDNILLDEHGHVHITDFNIATVVKGAERASSMAGTKPYMAPEVFQVYMDRGPGYSYPVDWWSLGITAYELLRGWRPYEIHSVTPIDEILNMFKVERVH---YSSTWCKGMVALLRKLLTKDPESRVSSLHDIQSVPYLADMNWDAVFKKALMPGFVPNKGRLNCDPTFELEEMILESKPLHKKKKRLAKNRSRDGTKDSCPLNGHLQHCLETVREEFIIFNREKLRRQQ 327
BLAST of Serine/threonine kinase 32A vs. Ensembl Human
Match: STK32A (serine/threonine kinase 32A [Source:HGNC Symbol;Acc:HGNC:28317]) HSP 1 Score: 283.108 bits (723), Expect = 3.098e-90 Identity = 164/353 (46.46%), Postives = 219/353 (62.04%), Query Frame = 1
Query: 151 NCEISFSDFEVLRAIXXXX-----XXXXXXXXXXXXXXXXNKVACIEKHAVSNVMREIRILLKLNHPFIVNLWYTFQDSNCQSMART*LFIIHLFQNESTINRQFVSHIGVKRTLDNEDLFVVVDLLTGGDMRFHSNNQTLKFSEKTVKLYICEISLVLDYLQSKRIIHRDIKPDNLLLDENGHIHLTDFNVATEL-QSNKSYSICGTKPYMAYEFFSDSLCNTGYSYEVDWWSLGIVAFELLVKKRPFKIQSNSSMNECRQIIENSKFYSHRYSDFISGEMLDLIFSLLRLESEYRVSSLKQIQENLLMKDINWNQVAKKQIEPDFKPSSNHLNCDPTFELEEMIIESKPLH 1191
N +++F FE+LRAIGKG +K KKM+AMKYMNK C+E++ V NV +E++I+ L HPF+VNLWY+FQD ED+F+VVDLL GGD+R+H Q + F E+TVKL+ICE+ + LDYLQ++RIIHRD+KPDN+LLDE+GH+H+TDFN+A L + + ++ GTKPYMA E FS S GYS+ VDWWSLG+ A+ELL +RP+ I+S++S E E + Y S EM+ L+ LL + R S L +Q M DINW+ V +K++ P F P+ LNCDPTFELEEMI+ESKPLH
Sbjct: 15 NEDVNFDHFEILRAIGKGSFGKVCIVQKNDTKKMYAMKYMNKQKCVERNEVRNVFKELQIMQGLEHPFLVNLWYSFQDE--------------------------------------EDMFMVVDLLLGGDLRYHLQ-QNVHFKEETVKLFICELVMALDYLQNQRIIHRDMKPDNILLDEHGHVHITDFNIAAMLPRETQITTMAGTKPYMAPEMFS-SRKGAGYSFAVDWWSLGVTAYELLRGRRPYHIRSSTSSKEIVHTFETTVV---TYPSAWSQEMVSLLKKLLEPNPDQRFSQLSDVQNFPYMNDINWDAVFQKRLIPGFIPNKGRLNCDPTFELEEMILESKPLH 324
BLAST of Serine/threonine kinase 32A vs. Ensembl Human
Match: STK32A (serine/threonine kinase 32A [Source:HGNC Symbol;Acc:HGNC:28317]) HSP 1 Score: 282.337 bits (721), Expect = 3.454e-90 Identity = 164/353 (46.46%), Postives = 219/353 (62.04%), Query Frame = 1
Query: 151 NCEISFSDFEVLRAIXXXX-----XXXXXXXXXXXXXXXXNKVACIEKHAVSNVMREIRILLKLNHPFIVNLWYTFQDSNCQSMART*LFIIHLFQNESTINRQFVSHIGVKRTLDNEDLFVVVDLLTGGDMRFHSNNQTLKFSEKTVKLYICEISLVLDYLQSKRIIHRDIKPDNLLLDENGHIHLTDFNVATEL-QSNKSYSICGTKPYMAYEFFSDSLCNTGYSYEVDWWSLGIVAFELLVKKRPFKIQSNSSMNECRQIIENSKFYSHRYSDFISGEMLDLIFSLLRLESEYRVSSLKQIQENLLMKDINWNQVAKKQIEPDFKPSSNHLNCDPTFELEEMIIESKPLH 1191
N +++F FE+LRAIGKG +K KKM+AMKYMNK C+E++ V NV +E++I+ L HPF+VNLWY+FQD ED+F+VVDLL GGD+R+H Q + F E+TVKL+ICE+ + LDYLQ++RIIHRD+KPDN+LLDE+GH+H+TDFN+A L + + ++ GTKPYMA E FS S GYS+ VDWWSLG+ A+ELL +RP+ I+S++S E E + Y S EM+ L+ LL + R S L +Q M DINW+ V +K++ P F P+ LNCDPTFELEEMI+ESKPLH
Sbjct: 15 NEDVNFDHFEILRAIGKGSFGKVCIVQKNDTKKMYAMKYMNKQKCVERNEVRNVFKELQIMQGLEHPFLVNLWYSFQDE--------------------------------------EDMFMVVDLLLGGDLRYHLQ-QNVHFKEETVKLFICELVMALDYLQNQRIIHRDMKPDNILLDEHGHVHITDFNIAAMLPRETQITTMAGTKPYMAPEMFS-SRKGAGYSFAVDWWSLGVTAYELLRGRRPYHIRSSTSSKEIVHTFETTVV---TYPSAWSQEMVSLLKKLLEPNPDQRFSQLSDVQNFPYMNDINWDAVFQKRLIPGFIPNKGRLNCDPTFELEEMILESKPLH 324
BLAST of Serine/threonine kinase 32A vs. Ensembl Human
Match: STK32C (serine/threonine kinase 32C [Source:HGNC Symbol;Acc:HGNC:21332]) HSP 1 Score: 278.1 bits (710), Expect = 6.733e-89 Identity = 155/364 (42.58%), Postives = 228/364 (62.64%), Query Frame = 1
Query: 256 NKVACIEKHAVSNVMREIRILLKLNHPFIVNLWYTFQDSNCQSMART*LFIIHLFQNESTINRQFVSHIGVKRTLDNEDLFVVVDLLTGGDMRFHSNNQTLKFSEKTVKLYICEISLVLDYLQSKRIIHRDIKPDNLLLDENGHIHLTDFNVATELQSN-KSYSICGTKPYMAYEFFSDSL-CNTGYSYEVDWWSLGIVAFELLVKKRPFKIQSNSSMNECRQIIENSKFYSHRYSDFISGEMLDLIFSLLRLESEYRVSSLKQIQENLLMKDINWNQVAKKQIEPDFKPSSNHLNCDPTFELEEMIIESKPLHKKEKRLAKQL-----KNNKNQMNSXXXXXXXXXXXXFTVFNRESFLKKEE 1326
NK CIE+ V NV RE+ IL ++ H F+VNLWY+FQD ED+F+VVDLL GGD+R+H Q ++FSE TV+LYICE++L LDYL+ + IIHRD+KPDN+LLDE GH HLTDFN+AT ++ ++ ++ GTKPYMA E F + TGYS+EVDWWS+G++A+ELL RP+ I S++++ Q+ S +Y S EM+ L+ LL + E+R+SSL+ +Q + + W+ +++K++EP F P+ L+CDPTFELEEMI+ES+PLHKK+KRLAK +++ N L++ L+ ++++F +FNRE + ++
Sbjct: 8 NKQQCIERDEVRNVFRELEILQEIEHVFLVNLWYSFQD--------------------------------------EEDMFMVVDLLLGGDLRYHLQ-QNVQFSEDTVRLYICEMALALDYLRGQHIIHRDVKPDNILLDERGHAHLTDFNIATIIKDGERATALAGTKPYMAPEIFHSFVNGGTGYSFEVDWWSVGVMAYELLRGWRPYDIHSSNAVESLVQLFST---VSVQYVPTWSKEMVALLRKLLTVNPEHRLSSLQDVQAAPALAGVLWDHLSEKRVEPGFVPNKGRLHCDPTFELEEMILESRPLHKKKKRLAKNKSRDNSRDSSQSENDYLQDCLDAIQQDFVIFNREKLKRSQD 329
BLAST of Serine/threonine kinase 32A vs. Ensembl Celegans
Match: M03C11.1 (pep chromosome:WBcel235:III:10393389:10396081:-1 gene:WBGene00010838.1 transcript:M03C11.1.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:M03C11.1) HSP 1 Score: 228.409 bits (581), Expect = 5.829e-70 Identity = 121/316 (38.29%), Postives = 179/316 (56.65%), Query Frame = 1
Query: 256 NKVACIEKHAVSNVMREIRILLKLNHPFIVNLWYTFQDSNCQSMART*LFIIHLFQNESTINRQFVSHIGVKRTLDNEDLFVVVDLLTGGDMRFHSNNQTLKFSEKTVKLYICEISLVLDYLQSKRIIHRDIKPDNLLLDENGHIHLTDFNVATELQSNK-SYSICGTKPYMAYEFFSDSL-CNTGYSYEVDWWSLGIVAFELLVKKRPFKIQSNSSMNECRQIIENSKFYSHRYSDFISGEMLDLIFSLLRLESEYRVSSLKQIQENLLMKDINWNQVAKKQIEPDFKPSSNHLNCDPTFELEEMIIESKPLHKK 1197
NK CIEK +NV+RE+ +L K++HPFIVNLWYTFQD + +++V DLL GGD+R+H + Q KF+E KLY+CEI L ++YL +I+HRDIKP+N+LLDE GH HLTD N+AT+L+ ++ + S GT+PYMA E ++ L GY VDWW+LG+ +E+L + PF+ S + E S S Y +++ I S+L+ + E R+ L+ I+++ + I++ V +K+ P F P LNCDP +ELEE I+ S P+H++
Sbjct: 60 NKRRCIEKGVAANVIRELTLLSKMSHPFIVNLWYTFQDGDY--------------------------------------MYMVSDLLLGGDLRYHLSQQG-KFAEDRAKLYLCEICLAVEYLHEMKIVHRDIKPENILLDEQGHAHLTDLNLATQLEDDQLATSYSGTRPYMAPEIYATYLEIEDGYDSRVDWWALGVCFYEMLRGRTPFEFSSRTKPEEAYVAFRES---SIPYPAHWPTDLIQFINSMLKFDKEKRLVGLEAIKKHSYTERIDFKSVFEKKPSPVFIPCKEGLNCDPMYELEERILVSTPIHRR 333
BLAST of Serine/threonine kinase 32A vs. Ensembl Celegans
Match: F47F2.1 (cAMP-dependent protein kinase, catalytic subunit-like [Source:UniProtKB/Swiss-Prot;Acc:Q7JP68]) HSP 1 Score: 139.428 bits (350), Expect = 1.145e-37 Identity = 88/309 (28.48%), Postives = 155/309 (50.16%), Query Frame = 1
Query: 292 NVMREIRILLKLNHPFIVNLWYTFQDSNCQSMART*LFIIHLFQNESTINRQFVSHIGVKRTLDNEDLFVVVDLLTGGDMRFHSNNQTLKFSEKTVKLYICEISLVLDYLQSKRIIHRDIKPDNLLLDENGHIHLTDFNVATELQSNKSYSICGTKPYMAYEFFSDSLCNTGYSYEVDWWSLGIVAFELLVKKRPFKIQSNSSMNECRQIIENSKFYSHRYSDFISGEMLDLIFSLLRLESEYRVSSLK----QIQENLLMKDINWNQVAKKQIEPDFKPSSNHLNCDPTFELEEMIIESKPLHKKEKR 1206
+V E R+LL+L HPFIV ++ + +DSN L+++++ + GG+M F + FS + Y EI L+Y+ S I++RD+KP+NL+L + GHI + DF A EL+ +++Y+ICGT Y+A E SL TG++ VDWW+LGI+ +E++V K PF+ ++ S + + IIE+ + ++ ++ + DL+ LL ++ R+ +K ++++ + +NW+ ++EP P+ H F+ E PL + R
Sbjct: 6 HVHNEKRVLLQLKHPFIVKMYASEKDSN--------------------------------------HLYMIMEFVPGGEM-FSYLRASRSFSNSMARFYASEIVCALEYIHSLGIVYRDLKPENLMLSKEGHIKMADFGFAKELR-DRTYTICGTPDYLAPE----SLARTGHNKGVDWWALGILIYEMMVGKPPFRGKTTSEIYDA--IIEHKLKFPRSFN--LAAK--DLVKKLLEVDRTQRIGCMKNGTQDVKDHKWFEKVNWDDTLHLRVEPPIVPTLYHPGDTGNFDDYEEDTTGGPLCSQRDR 264
BLAST of Serine/threonine kinase 32A vs. Ensembl Celegans
Match: F47F2.1 (cAMP-dependent protein kinase, catalytic subunit-like [Source:UniProtKB/Swiss-Prot;Acc:Q7JP68]) HSP 1 Score: 139.428 bits (350), Expect = 1.145e-37 Identity = 88/309 (28.48%), Postives = 155/309 (50.16%), Query Frame = 1
Query: 292 NVMREIRILLKLNHPFIVNLWYTFQDSNCQSMART*LFIIHLFQNESTINRQFVSHIGVKRTLDNEDLFVVVDLLTGGDMRFHSNNQTLKFSEKTVKLYICEISLVLDYLQSKRIIHRDIKPDNLLLDENGHIHLTDFNVATELQSNKSYSICGTKPYMAYEFFSDSLCNTGYSYEVDWWSLGIVAFELLVKKRPFKIQSNSSMNECRQIIENSKFYSHRYSDFISGEMLDLIFSLLRLESEYRVSSLK----QIQENLLMKDINWNQVAKKQIEPDFKPSSNHLNCDPTFELEEMIIESKPLHKKEKR 1206
+V E R+LL+L HPFIV ++ + +DSN L+++++ + GG+M F + FS + Y EI L+Y+ S I++RD+KP+NL+L + GHI + DF A EL+ +++Y+ICGT Y+A E SL TG++ VDWW+LGI+ +E++V K PF+ ++ S + + IIE+ + ++ ++ + DL+ LL ++ R+ +K ++++ + +NW+ ++EP P+ H F+ E PL + R
Sbjct: 6 HVHNEKRVLLQLKHPFIVKMYASEKDSN--------------------------------------HLYMIMEFVPGGEM-FSYLRASRSFSNSMARFYASEIVCALEYIHSLGIVYRDLKPENLMLSKEGHIKMADFGFAKELR-DRTYTICGTPDYLAPE----SLARTGHNKGVDWWALGILIYEMMVGKPPFRGKTTSEIYDA--IIEHKLKFPRSFN--LAAK--DLVKKLLEVDRTQRIGCMKNGTQDVKDHKWFEKVNWDDTLHLRVEPPIVPTLYHPGDTGNFDDYEEDTTGGPLCSQRDR 264
BLAST of Serine/threonine kinase 32A vs. Ensembl Celegans
Match: F47F2.1 (cAMP-dependent protein kinase, catalytic subunit-like [Source:UniProtKB/Swiss-Prot;Acc:Q7JP68]) HSP 1 Score: 139.428 bits (350), Expect = 1.145e-37 Identity = 88/309 (28.48%), Postives = 155/309 (50.16%), Query Frame = 1
Query: 292 NVMREIRILLKLNHPFIVNLWYTFQDSNCQSMART*LFIIHLFQNESTINRQFVSHIGVKRTLDNEDLFVVVDLLTGGDMRFHSNNQTLKFSEKTVKLYICEISLVLDYLQSKRIIHRDIKPDNLLLDENGHIHLTDFNVATELQSNKSYSICGTKPYMAYEFFSDSLCNTGYSYEVDWWSLGIVAFELLVKKRPFKIQSNSSMNECRQIIENSKFYSHRYSDFISGEMLDLIFSLLRLESEYRVSSLK----QIQENLLMKDINWNQVAKKQIEPDFKPSSNHLNCDPTFELEEMIIESKPLHKKEKR 1206
+V E R+LL+L HPFIV ++ + +DSN L+++++ + GG+M F + FS + Y EI L+Y+ S I++RD+KP+NL+L + GHI + DF A EL+ +++Y+ICGT Y+A E SL TG++ VDWW+LGI+ +E++V K PF+ ++ S + + IIE+ + ++ ++ + DL+ LL ++ R+ +K ++++ + +NW+ ++EP P+ H F+ E PL + R
Sbjct: 6 HVHNEKRVLLQLKHPFIVKMYASEKDSN--------------------------------------HLYMIMEFVPGGEM-FSYLRASRSFSNSMARFYASEIVCALEYIHSLGIVYRDLKPENLMLSKEGHIKMADFGFAKELR-DRTYTICGTPDYLAPE----SLARTGHNKGVDWWALGILIYEMMVGKPPFRGKTTSEIYDA--IIEHKLKFPRSFN--LAAK--DLVKKLLEVDRTQRIGCMKNGTQDVKDHKWFEKVNWDDTLHLRVEPPIVPTLYHPGDTGNFDDYEEDTTGGPLCSQRDR 264
BLAST of Serine/threonine kinase 32A vs. Ensembl Celegans
Match: F47F2.1 (cAMP-dependent protein kinase, catalytic subunit-like [Source:UniProtKB/Swiss-Prot;Acc:Q7JP68]) HSP 1 Score: 140.584 bits (353), Expect = 1.529e-37 Identity = 88/317 (27.76%), Postives = 157/317 (49.53%), Query Frame = 1
Query: 268 CIEKHAVSNVMREIRILLKLNHPFIVNLWYTFQDSNCQSMART*LFIIHLFQNESTINRQFVSHIGVKRTLDNEDLFVVVDLLTGGDMRFHSNNQTLKFSEKTVKLYICEISLVLDYLQSKRIIHRDIKPDNLLLDENGHIHLTDFNVATELQSNKSYSICGTKPYMAYEFFSDSLCNTGYSYEVDWWSLGIVAFELLVKKRPFKIQSNSSMNECRQIIENSKFYSHRYSDFISGEMLDLIFSLLRLESEYRVSSLK----QIQENLLMKDINWNQVAKKQIEPDFKPSSNHLNCDPTFELEEMIIESKPLHKKEKR 1206
++ +V E R+LL+L HPFIV ++ + +DSN L+++++ + GG+M F + FS + Y EI L+Y+ S I++RD+KP+NL+L + GHI + DF A EL+ +++Y+ICGT Y+A E SL TG++ VDWW+LGI+ +E++V K PF+ ++ S + + IIE+ + ++ ++ + DL+ LL ++ R+ +K ++++ + +NW+ ++EP P+ H F+ E PL + R
Sbjct: 53 VVDMRQTQHVHNEKRVLLQLKHPFIVKMYASEKDSN--------------------------------------HLYMIMEFVPGGEM-FSYLRASRSFSNSMARFYASEIVCALEYIHSLGIVYRDLKPENLMLSKEGHIKMADFGFAKELR-DRTYTICGTPDYLAPE----SLARTGHNKGVDWWALGILIYEMMVGKPPFRGKTTSEIYDA--IIEHKLKFPRSFN--LAAK--DLVKKLLEVDRTQRIGCMKNGTQDVKDHKWFEKVNWDDTLHLRVEPPIVPTLYHPGDTGNFDDYEEDTTGGPLCSQRDR 319
BLAST of Serine/threonine kinase 32A vs. Ensembl Fly
Match: CG32944 (gene:FBgn0052944 transcript:FBtr0290249) HSP 1 Score: 286.574 bits (732), Expect = 2.094e-91 Identity = 168/406 (41.38%), Postives = 248/406 (61.08%), Query Frame = 1
Query: 157 EISFSDFEVLRAIXXXX-----XXXXXXXXXXXXXXXXNKVACIEKHAVSNVMREIRILLKLNHPFIVNLWYTFQDSNCQSMART*LFIIHLFQNESTINRQFVSHIGVKRTLDNEDLFVVVDLLTGGDMRFHSNNQTLKFSEKTVKLYICEISLVLDYLQSKRIIHRDIKPDNLLLDENGHIHLTDFNVATELQSNK-SYSICGTKPYMAYEFFSDSLCN----TGYSYEVDWWSLGIVAFELLVKKRPFKIQSNSSMNECRQIIENSKFYSHRYSDFISGEMLDLIFSLLRLESEYRVSSLKQIQENLLMKDINWNQVAKKQIEPDFKPSSNHLNCDPTFELEEMIIESKPLHKKEKRLAKQLKNNKNQMNSXXXXXXXXXXXXFTVFNRESFLKKEENEKNFN 1344
+++F F++LRAIGKG +K+ ++AMKY+++ AC + A+ V++E+ +L L HPF+VNLW++FQD EDLF+V DLLTGGD+R+H N+ ++FSE++V L +CE+ L+YLQ+ R++HRDIKPDN+LLD+ GH HLTDFN+AT LQ N + S+ GTKPYMA E F LC GYSY VDWWSLG+VA+E+ RPF + SN+ + E + I+ N+ + RY S +DL+ LL R+S+ +++ + ++++I++ +V +K+I+P +KP +HLNCDP ELEEMI+ES+PLHKK+KRLAKQ ++ + L KEF V+NR LK++ E+ N
Sbjct: 18 DVNFDHFQILRAIGKGSFGKVCIVQKRDTGILYAMKYVSRSACEMRGALGGVIKEVELLSSLEHPFLVNLWFSFQD--------------------------------------EEDLFMVCDLLTGGDLRYHLQNR-VEFSEQSVALLVCELGSALEYLQANRVVHRDIKPDNILLDDAGHAHLTDFNIATRLQKNALACSMSGTKPYMAPEVF---LCALDEVAGYSYPVDWWSLGVVAYEMRGNIRPFVVHSNTPLAEIKNIL-NTPVHYPRY---WSSNFVDLLQRLLSTYPGARISTRQELHQTPMLRNIDFQRVLEKKIKPIYKPPEDHLNCDPCLELEEMIVESRPLHKKKKRLAKQRSAQRDS------DPETALVKEFIVYNRYKELKRKAMEQKEN 371
BLAST of Serine/threonine kinase 32A vs. Ensembl Fly
Match: CG32944 (gene:FBgn0052944 transcript:FBtr0339973) HSP 1 Score: 286.574 bits (732), Expect = 2.094e-91 Identity = 168/406 (41.38%), Postives = 248/406 (61.08%), Query Frame = 1
Query: 157 EISFSDFEVLRAIXXXX-----XXXXXXXXXXXXXXXXNKVACIEKHAVSNVMREIRILLKLNHPFIVNLWYTFQDSNCQSMART*LFIIHLFQNESTINRQFVSHIGVKRTLDNEDLFVVVDLLTGGDMRFHSNNQTLKFSEKTVKLYICEISLVLDYLQSKRIIHRDIKPDNLLLDENGHIHLTDFNVATELQSNK-SYSICGTKPYMAYEFFSDSLCN----TGYSYEVDWWSLGIVAFELLVKKRPFKIQSNSSMNECRQIIENSKFYSHRYSDFISGEMLDLIFSLLRLESEYRVSSLKQIQENLLMKDINWNQVAKKQIEPDFKPSSNHLNCDPTFELEEMIIESKPLHKKEKRLAKQLKNNKNQMNSXXXXXXXXXXXXFTVFNRESFLKKEENEKNFN 1344
+++F F++LRAIGKG +K+ ++AMKY+++ AC + A+ V++E+ +L L HPF+VNLW++FQD EDLF+V DLLTGGD+R+H N+ ++FSE++V L +CE+ L+YLQ+ R++HRDIKPDN+LLD+ GH HLTDFN+AT LQ N + S+ GTKPYMA E F LC GYSY VDWWSLG+VA+E+ RPF + SN+ + E + I+ N+ + RY S +DL+ LL R+S+ +++ + ++++I++ +V +K+I+P +KP +HLNCDP ELEEMI+ES+PLHKK+KRLAKQ ++ + L KEF V+NR LK++ E+ N
Sbjct: 18 DVNFDHFQILRAIGKGSFGKVCIVQKRDTGILYAMKYVSRSACEMRGALGGVIKEVELLSSLEHPFLVNLWFSFQD--------------------------------------EEDLFMVCDLLTGGDLRYHLQNR-VEFSEQSVALLVCELGSALEYLQANRVVHRDIKPDNILLDDAGHAHLTDFNIATRLQKNALACSMSGTKPYMAPEVF---LCALDEVAGYSYPVDWWSLGVVAYEMRGNIRPFVVHSNTPLAEIKNIL-NTPVHYPRY---WSSNFVDLLQRLLSTYPGARISTRQELHQTPMLRNIDFQRVLEKKIKPIYKPPEDHLNCDPCLELEEMIVESRPLHKKKKRLAKQRSAQRDS------DPETALVKEFIVYNRYKELKRKAMEQKEN 371
BLAST of Serine/threonine kinase 32A vs. Ensembl Fly
Match: CG32944 (gene:FBgn0052944 transcript:FBtr0290250) HSP 1 Score: 284.263 bits (726), Expect = 5.170e-89 Identity = 169/405 (41.73%), Postives = 247/405 (60.99%), Query Frame = 1
Query: 160 ISFSDFEVLRAIXXXX-----XXXXXXXXXXXXXXXXNKVACIEKHAVSNVMREIRILLKLNHPFIVNLWYTFQDSNCQSMART*LFIIHLFQNESTINRQFVSHIGVKRTLDNEDLFVVVDLLTGGDMRFHSNNQTLKFSEKTVKLYICEISLVLDYLQSKRIIHRDIKPDNLLLDENGHIHLTDFNVATELQSNK-SYSICGTKPYMAYEFFSDSLCN----TGYSYEVDWWSLGIVAFELLVKKRPFKIQSNSSMNECRQIIENSKFYSHRYSDFISGEMLDLIFSLLRLESEYRVSSLKQIQENLLMKDINWNQVAKKQIEPDFKPSSNHLNCDPTFELEEMIIESKPLHKKEKRLAKQLKNNKNQMNSXXXXXXXXXXXXFTVFNRESFLKKEENEKNFN 1344
I+F F++LRAIGKG +K+ ++AMKY+++ AC + A+ V++E+ +L L HPF+VNLW++FQD EDLF+V DLLTGGD+R+H N+ ++FSE++V L +CE+ L+YLQ+ R++HRDIKPDN+LLD+ GH HLTDFN+AT LQ N + S+ GTKPYMA E F LC GYSY VDWWSLG+VA+E+ RPF + SN+ + E + I+ N+ + RY S +DL+ LL R+S+ +++ + ++++I++ +V +K+I+P +KP +HLNCDP ELEEMI+ES+PLHKK+KRLAKQ ++ + L KEF V+NR LK++ E+ N
Sbjct: 146 INFDHFQILRAIGKGSFGKVCIVQKRDTGILYAMKYVSRSACEMRGALGGVIKEVELLSSLEHPFLVNLWFSFQD--------------------------------------EEDLFMVCDLLTGGDLRYHLQNR-VEFSEQSVALLVCELGSALEYLQANRVVHRDIKPDNILLDDAGHAHLTDFNIATRLQKNALACSMSGTKPYMAPEVF---LCALDEVAGYSYPVDWWSLGVVAYEMRGNIRPFVVHSNTPLAEIKNIL-NTPVHYPRY---WSSNFVDLLQRLLSTYPGARISTRQELHQTPMLRNIDFQRVLEKKIKPIYKPPEDHLNCDPCLELEEMIVESRPLHKKKKRLAKQRSAQRDS------DPETALVKEFIVYNRYKELKRKAMEQKEN 498
BLAST of Serine/threonine kinase 32A vs. Ensembl Fly
Match: S6kII (gene:FBgn0262866 transcript:FBtr0333715) HSP 1 Score: 137.502 bits (345), Expect = 3.760e-34 Identity = 85/279 (30.47%), Postives = 140/279 (50.18%), Query Frame = 1
Query: 304 EIRILLKLNHPFIVNLWYTFQDSNCQSMART*LFIIHLFQNESTINRQFVSHIGVKRTLDNEDLFVVVDLLTGGDMRFHSNNQTLKFSEKTVKLYICEISLVLDYLQSKRIIHRDIKPDNLLLDENGHIHLTDFNVATE-LQSNKSYSICGTKPYMAYEFFSDSLCNTGYSYEVDWWSLGIVAFELLVKKRPFKIQS-NSSMNECRQIIENSKFYSHRYSDFISGEMLDLIFSLLRLESEYRVSSLKQ----IQENLLMKDINWNQVAKKQIEPDFKPS 1122
E +IL + H FIV L Y FQ L++++D L GGD+ F ++ + F+E+ VK Y+ E++L +++L + II+RD+KP+N+LLDE+GHI LTDF ++ + L +K+YS CGT YMA E + G+ + DWWS G++ +E+L PF Q+ +MN+ I SK + +S E L+ +L + + R+ + Q I+ + I+W ++ +KQ+ P F P+
Sbjct: 249 ERKILADVGHAFIVRLHYAFQTPG--------------------------------------KLYLILDFLRGGDL-FTRLSKEVMFTEEDVKFYLAELALAMNHLHTLGIIYRDLKPENILLDEHGHIALTDFGLSKQPLDGSKTYSFCGTVEYMAPEIVN----RKGHDFAADWWSFGVLMYEMLTGNLPFHGQTRQETMNQ----ILRSKL---GMPENLSPEAQSLLRALFKRNPQNRLGAGAQGILDIKAHCFFATIDWVRLERKQVRPPFIPA 477 HSP 2 Score: 60.8474 bits (146), Expect = 1.958e-9 Identity = 61/280 (21.79%), Postives = 116/280 (41.43%), Query Frame = 1
Query: 304 EIRILLKL-NHPFIVNLWYTFQDSNCQSMART*LFIIHLFQNESTINRQFVSHIGVKRTLDNEDLFVVVDLLTGGDM--RFHSNNQTLKFSEKTVKLYICEISLVLDYLQSKRIIHRDIKPDNLLLDENGH----IHLTDFNVATELQSNKS--YSICGTKPYMAYEFFSDSLCNTGYSYEVDWWSLGIVAFELLVKKRPFKIQSNSSMNECRQIIENSK--FYSHRYSDFISGEMLDLIFSLLRLESEYRVSSLKQIQENLLMKDINWN-QVAKKQIEP 1107
E+ I+L+ NHP IV L+ ++D+ ++V++LL GG++ R + Q E + I+ + YL ++HRD+KP N++ + L D A +L+++ + C T ++A E L GY D WSLG++ + +L + PF N S + + I + + F S R++ IS +L+ +L + E R ++ + ++ + L + Q+ + + P
Sbjct: 618 EVEIMLRYGNHPNIVTLYSVYEDAGSA--------------------------------------YLVMELLKGGELLDRILAVGQ---MCESEASAVLRTIASAVAYLHEHGVVHRDLKPSNMIYASMRQTPETLKLCDLGFAKQLRADNGLLMTPCYTANFVAPEV----LKRQGYDLACDIWSLGVLLYIMLSGRTPFASTPNDSPDVILKRIGSGQIDFTSSRWA-LISVPAKELLRQMLHIVPENRPTAARILEHDWLREQFAGGVQLTEYAVAP 851
BLAST of Serine/threonine kinase 32A vs. Ensembl Fly
Match: S6kII (gene:FBgn0262866 transcript:FBtr0077360) HSP 1 Score: 137.502 bits (345), Expect = 3.760e-34 Identity = 85/279 (30.47%), Postives = 140/279 (50.18%), Query Frame = 1
Query: 304 EIRILLKLNHPFIVNLWYTFQDSNCQSMART*LFIIHLFQNESTINRQFVSHIGVKRTLDNEDLFVVVDLLTGGDMRFHSNNQTLKFSEKTVKLYICEISLVLDYLQSKRIIHRDIKPDNLLLDENGHIHLTDFNVATE-LQSNKSYSICGTKPYMAYEFFSDSLCNTGYSYEVDWWSLGIVAFELLVKKRPFKIQS-NSSMNECRQIIENSKFYSHRYSDFISGEMLDLIFSLLRLESEYRVSSLKQ----IQENLLMKDINWNQVAKKQIEPDFKPS 1122
E +IL + H FIV L Y FQ L++++D L GGD+ F ++ + F+E+ VK Y+ E++L +++L + II+RD+KP+N+LLDE+GHI LTDF ++ + L +K+YS CGT YMA E + G+ + DWWS G++ +E+L PF Q+ +MN+ I SK + +S E L+ +L + + R+ + Q I+ + I+W ++ +KQ+ P F P+
Sbjct: 249 ERKILADVGHAFIVRLHYAFQTPG--------------------------------------KLYLILDFLRGGDL-FTRLSKEVMFTEEDVKFYLAELALAMNHLHTLGIIYRDLKPENILLDEHGHIALTDFGLSKQPLDGSKTYSFCGTVEYMAPEIVN----RKGHDFAADWWSFGVLMYEMLTGNLPFHGQTRQETMNQ----ILRSKL---GMPENLSPEAQSLLRALFKRNPQNRLGAGAQGILDIKAHCFFATIDWVRLERKQVRPPFIPA 477 HSP 2 Score: 60.8474 bits (146), Expect = 1.958e-9 Identity = 61/280 (21.79%), Postives = 116/280 (41.43%), Query Frame = 1
Query: 304 EIRILLKL-NHPFIVNLWYTFQDSNCQSMART*LFIIHLFQNESTINRQFVSHIGVKRTLDNEDLFVVVDLLTGGDM--RFHSNNQTLKFSEKTVKLYICEISLVLDYLQSKRIIHRDIKPDNLLLDENGH----IHLTDFNVATELQSNKS--YSICGTKPYMAYEFFSDSLCNTGYSYEVDWWSLGIVAFELLVKKRPFKIQSNSSMNECRQIIENSK--FYSHRYSDFISGEMLDLIFSLLRLESEYRVSSLKQIQENLLMKDINWN-QVAKKQIEP 1107
E+ I+L+ NHP IV L+ ++D+ ++V++LL GG++ R + Q E + I+ + YL ++HRD+KP N++ + L D A +L+++ + C T ++A E L GY D WSLG++ + +L + PF N S + + I + + F S R++ IS +L+ +L + E R ++ + ++ + L + Q+ + + P
Sbjct: 618 EVEIMLRYGNHPNIVTLYSVYEDAGSA--------------------------------------YLVMELLKGGELLDRILAVGQ---MCESEASAVLRTIASAVAYLHEHGVVHRDLKPSNMIYASMRQTPETLKLCDLGFAKQLRADNGLLMTPCYTANFVAPEV----LKRQGYDLACDIWSLGVLLYIMLSGRTPFASTPNDSPDVILKRIGSGQIDFTSSRWA-LISVPAKELLRQMLHIVPENRPTAARILEHDWLREQFAGGVQLTEYAVAP 851
BLAST of Serine/threonine kinase 32A vs. Ensembl Zebrafish
Match: stk32a (serine/threonine kinase 32A [Source:ZFIN;Acc:ZDB-GENE-091204-271]) HSP 1 Score: 196.438 bits (498), Expect = 1.771e-59 Identity = 99/194 (51.03%), Postives = 135/194 (69.59%), Query Frame = 1
Query: 640 HRDIKPDNLLLDENGHIHLTDFNVATELQSN-KSYSICGTKPYMAYEFFS-DSLCNTGYSYEVDWWSLGIVAFELLVKKRPFKIQSNSSMNECRQIIENSK-FYSHRYSDFISGEMLDLIFSLLRLESEYRVSSLKQIQENLLMKDINWNQVAKKQIEPDFKPSSNHLNCDPTFELEEMIIESKPLHKKEKRLA 1212
HRDIKPDN+LLDE+GH HLTDFN+A ++ + K+ SI GTKPYMA E F + GYS++VDWWSLGI A+ELL +RP+ +++N+ NE Q ++ Y +S I L+ LL ++++ R+SSL ++Q+ + D+NW+ V KQI P F P+ LNCDPTFELEEMI+ESKPLHKK+KRL+
Sbjct: 1 HRDIKPDNILLDEHGHAHLTDFNIAAIVKEDLKATSIAGTKPYMAPELFQLVEGTHPGYSFDVDWWSLGITAYELLRGQRPYIMRTNTPANEILQTFHKAQPCYPAAWSSGIKS----LLNMLLCVDAQKRISSLSELQDLEYLSDVNWDAVLSKQIPPGFLPNRRRLNCDPTFELEEMILESKPLHKKKKRLS 190
BLAST of Serine/threonine kinase 32A vs. Ensembl Zebrafish
Match: rps6kal (ribosomal protein S6 kinase a, like [Source:NCBI gene;Acc:337670]) HSP 1 Score: 150.214 bits (378), Expect = 1.823e-38 Identity = 93/290 (32.07%), Postives = 148/290 (51.03%), Query Frame = 1
Query: 313 ILLKLNHPFIVNLWYTFQDSNCQSMART*LFIIHLFQNESTINRQFVSHIGVKRTLDNEDLFVVVDLLTGGDMRFHSNNQTLKFSEKTVKLYICEISLVLDYLQSKRIIHRDIKPDNLLLDENGHIHLTDFNVATEL--QSNKSYSICGTKPYMAYEFFSDSLCNTGYSYEVDWWSLGIVAFELLVKKRPFKIQSNSSMNECRQIIENSKFYSHRYSDFISGEMLDLIFSLLRLESEYRVSS----LKQIQENLLMKDINWNQVAKKQIEPDFKPSSNHLN---C-DPTF 1152
IL+++NHPFIV L Y FQ L++++D L GGD+ F ++ + F+E+ VK Y+ E++L LD+L + I++RD+KP+N+LLDE GHI LTDF ++ E Q K+YS CGT YMA E + G++ DWWSLG++ FE+L PF+ NE +I +K F+S E L+ L + R+ + +++I+ + I+WN++ +++++P FKP+S + C DP F
Sbjct: 120 ILVEVNHPFIVKLHYAFQTEG--------------------------------------KLYLILDFLRGGDV-FTRLSKEVMFTEEDVKFYLAELALALDHLHNLGIVYRDLKPENILLDEAGHIKLTDFGLSKESVDQDKKAYSFCGTVEYMAPEVVN----RRGHTQSADWWSLGVLMFEMLTGTLPFQ---GKDRNETMNMILKAKL---GMPQFLSLEAQSLLRMLFKRNPSNRLGAGPDGVEEIKRHTFFSTIDWNKLYRRELQPPFKPASGKPDDTFCFDPEF 360 HSP 2 Score: 78.1814 bits (191), Expect = 7.747e-15 Identity = 61/237 (25.74%), Postives = 111/237 (46.84%), Query Frame = 1
Query: 493 LFVVVDLLTGGDMRFHSNNQTLKFSEKTVKLYICEISLVLDYLQSKRIIHRDIKPDNLL-LDENGH---IHLTDFNVATELQSNKS--YSICGTKPYMAYEFFSDSLCNTGYSYEVDWWSLGIVAFELLVKKRPFKIQSNSSMNECRQIIENSKF-YSHRYSDFISGEMLDLIFSLLRLESEYRVSSLKQIQEN-LLMKDINWNQVAKKQIEPDFKPSS--------NHLNCDPTFE 1155
+++V +L+ GG++ Q FSE+ + I+ +DYL + ++HRD+KP N+L +D++G+ I + DF A +L+ + + C T ++A E L GY D WSLG++ + +L PF N + E I + KF S D +S DL+ +L ++ +R ++ + ++ + + +D N + + P + NH C P E
Sbjct: 478 VYLVTELMKGGELLDKILRQKF-FSEREASAVLYTITKTVDYLHCQGVVHRDLKPSNILYMDDSGNPDSIRICDFGFAKQLRGDNGLLLTPCYTANFVAPEV----LMRQGYDAACDIWSLGVLLYTMLAGYTPFANGPNDTPEEILLRIGSGKFSLSGGNWDSVSDSSKDLLSHMLHVDPHHRYTAEQVLKHSWIACRDQNPHFQLTRHEAPHLVKGAMAATYSALNHKTCKPVLE 709
BLAST of Serine/threonine kinase 32A vs. Ensembl Zebrafish
Match: rps6kal (ribosomal protein S6 kinase a, like [Source:NCBI gene;Acc:337670]) HSP 1 Score: 149.828 bits (377), Expect = 2.406e-38 Identity = 93/290 (32.07%), Postives = 148/290 (51.03%), Query Frame = 1
Query: 313 ILLKLNHPFIVNLWYTFQDSNCQSMART*LFIIHLFQNESTINRQFVSHIGVKRTLDNEDLFVVVDLLTGGDMRFHSNNQTLKFSEKTVKLYICEISLVLDYLQSKRIIHRDIKPDNLLLDENGHIHLTDFNVATEL--QSNKSYSICGTKPYMAYEFFSDSLCNTGYSYEVDWWSLGIVAFELLVKKRPFKIQSNSSMNECRQIIENSKFYSHRYSDFISGEMLDLIFSLLRLESEYRVSS----LKQIQENLLMKDINWNQVAKKQIEPDFKPSSNHLN---C-DPTF 1152
IL+++NHPFIV L Y FQ L++++D L GGD+ F ++ + F+E+ VK Y+ E++L LD+L + I++RD+KP+N+LLDE GHI LTDF ++ E Q K+YS CGT YMA E + G++ DWWSLG++ FE+L PF+ NE +I +K F+S E L+ L + R+ + +++I+ + I+WN++ +++++P FKP+S + C DP F
Sbjct: 120 ILVEVNHPFIVKLHYAFQTEG--------------------------------------KLYLILDFLRGGDV-FTRLSKEVMFTEEDVKFYLAELALALDHLHNLGIVYRDLKPENILLDEAGHIKLTDFGLSKESVDQDKKAYSFCGTVEYMAPEVVN----RRGHTQSADWWSLGVLMFEMLTGTLPFQ---GKDRNETMNMILKAKL---GMPQFLSLEAQSLLRMLFKRNPSNRLGAGPDGVEEIKRHTFFSTIDWNKLYRRELQPPFKPASGKPDDTFCFDPEF 360 HSP 2 Score: 78.1814 bits (191), Expect = 9.474e-15 Identity = 61/237 (25.74%), Postives = 111/237 (46.84%), Query Frame = 1
Query: 493 LFVVVDLLTGGDMRFHSNNQTLKFSEKTVKLYICEISLVLDYLQSKRIIHRDIKPDNLL-LDENGH---IHLTDFNVATELQSNKS--YSICGTKPYMAYEFFSDSLCNTGYSYEVDWWSLGIVAFELLVKKRPFKIQSNSSMNECRQIIENSKF-YSHRYSDFISGEMLDLIFSLLRLESEYRVSSLKQIQEN-LLMKDINWNQVAKKQIEPDFKPSS--------NHLNCDPTFE 1155
+++V +L+ GG++ Q FSE+ + I+ +DYL + ++HRD+KP N+L +D++G+ I + DF A +L+ + + C T ++A E L GY D WSLG++ + +L PF N + E I + KF S D +S DL+ +L ++ +R ++ + ++ + + +D N + + P + NH C P E
Sbjct: 487 VYLVTELMKGGELLDKILRQKF-FSEREASAVLYTITKTVDYLHCQGVVHRDLKPSNILYMDDSGNPDSIRICDFGFAKQLRGDNGLLLTPCYTANFVAPEV----LMRQGYDAACDIWSLGVLLYTMLAGYTPFANGPNDTPEEILLRIGSGKFSLSGGNWDSVSDSSKDLLSHMLHVDPHHRYTAEQVLKHSWIACRDQNPHFQLTRHEAPHLVKGAMAATYSALNHKTCKPVLE 718
BLAST of Serine/threonine kinase 32A vs. Ensembl Zebrafish
Match: rps6ka3b (ribosomal protein S6 kinase, polypeptide 3b [Source:ZFIN;Acc:ZDB-GENE-070209-74]) HSP 1 Score: 149.058 bits (375), Expect = 4.353e-38 Identity = 92/297 (30.98%), Postives = 146/297 (49.16%), Query Frame = 1
Query: 313 ILLKLNHPFIVNLWYTFQDSNCQSMART*LFIIHLFQNESTINRQFVSHIGVKRTLDNEDLFVVVDLLTGGDMRFHSNNQTLKFSEKTVKLYICEISLVLDYLQSKRIIHRDIKPDNLLLDENGHIHLTDFNVATEL--QSNKSYSICGTKPYMAYEFFSDSLCNTGYSYEVDWWSLGIVAFELLVKKRPFKIQSNSSMNECRQIIENSKFYSHRYSDFISGEMLDLIFSLLRLESEYRVSS----LKQIQENLLMKDINWNQVAKKQIEPDFKPSSNHLNCDPTFELEEMIIESKP 1185
IL+++NHPFIV L Y FQ L++++D L GGD+ F ++ + F+E+ VK Y+ E++L LD+L II+RD+KP+N+LLDE+GHI LTDF ++ E NK+YS CGT YMA E + G++Y DWWS G++ +E+L PF+ E +I +K F+S E L+ SL + R+ + +++I+ + I+WN++ +++ P FKP++ D TF + P
Sbjct: 120 ILVEVNHPFIVKLHYAFQTEG--------------------------------------KLYLILDFLRGGDL-FTRLSKEVMFTEEDVKFYLAELALALDHLHGLGIIYRDLKPENILLDEDGHIKLTDFGLSKESIDHENKAYSFCGTVEYMAPEVVN----RRGHTYSADWWSYGVLMYEMLTGTLPFQ---GKDRKETMTMILKAKL---GMPQFLSSEAQSLLRSLFKRNPTNRLGAGPDGVEEIKRHPFYVSIDWNKLFRRESHPPFKPATG--RPDDTFYFDPEFTAKTP 365 HSP 2 Score: 74.7146 bits (182), Expect = 1.010e-13 Identity = 54/211 (25.59%), Postives = 104/211 (49.29%), Query Frame = 1
Query: 436 INRQFVSHIGVKRTLDNEDLFVVVDLLTGGDMRFHSNNQTLKFSEKTVKLYICEISLVLDYLQSKRIIHRDIKPDNLL-LDENGH---IHLTDFNVATELQSNKS--YSICGTKPYMAYEFFSDSLCNTGYSYEVDWWSLGIVAFELLVKKRPFKIQSNSSMNECRQIIENSKF-YSHRYSDFISGEMLDLIFSLLRLESEYRVSSLKQIQ 1047
I + + VK D +++V +LL GG++ Q FSE+ + I+ + YL ++ ++HRD+KP N+L +DE+G+ I + DF A +L++ + C T ++A E L GY D WSLG++ + +L PF + E I + +F + + + +S + DL+ +L ++ R+++ + ++
Sbjct: 439 IQKSTMMEYAVKVYDDGRTVYLVTELLKGGELLDKILRQKF-FSEREACAVLHTITKTVAYLHAQGVVHRDLKPSNILYVDESGNPESIRICDFGFAKQLRAENGLLMTPCYTANFVAPEV----LKKQGYDAACDIWSLGVLLYTMLTGFTPFANGPEDTPEEILARIGSGQFSLTGGFWNSVSCQAKDLVSKMLHVDPHQRLTAAQVLK 644
BLAST of Serine/threonine kinase 32A vs. Ensembl Zebrafish
Match: rps6ka2 (ribosomal protein S6 kinase, polypeptide 2 [Source:ZFIN;Acc:ZDB-GENE-090827-1]) HSP 1 Score: 148.673 bits (374), Expect = 6.610e-38 Identity = 89/290 (30.69%), Postives = 146/290 (50.34%), Query Frame = 1
Query: 313 ILLKLNHPFIVNLWYTFQDSNCQSMART*LFIIHLFQNESTINRQFVSHIGVKRTLDNEDLFVVVDLLTGGDMRFHSNNQTLKFSEKTVKLYICEISLVLDYLQSKRIIHRDIKPDNLLLDENGHIHLTDFNVATEL--QSNKSYSICGTKPYMAYEFFSDSLCNTGYSYEVDWWSLGIVAFELLVKKRPFKIQSNSSMNECRQIIENSKFYSHRYSDFISGEMLDLIFSLLRLESEYRVSS----LKQIQENLLMKDINWNQVAKKQIEPDFKPS----SNHLNCDPTF 1152
IL ++NHPFIV L Y FQ L++++D L GGD+ F ++ + F+E+ VK Y+ E++L LD+L S II+RD+KP+N+LLDE GHI +TDF ++ E ++YS CGT YMA E + G++ DWWS G++ FE+L PF+ E +I +K F+S E+ L+ +L + R+ + +++I+ ++ I+WN++ +++I+P FKP+ + + DP F
Sbjct: 112 ILAEVNHPFIVKLHYAFQTEG--------------------------------------KLYLILDFLRGGDL-FTRLSKEVMFTEEDVKFYLAELALALDHLHSLGIIYRDLKPENILLDEEGHIKITDFGLSKEAIDHDKRAYSFCGTIEYMAPEVVN----RRGHTQSADWWSFGVLMFEMLTGSLPFQ---GKDRKETMALILKAKL---GMPQFLSPEVQSLLRALFKRNPSNRLGAGPDGVEEIKRHIFFATIDWNKLYRREIKPPFKPAVGRPEDTFHFDPEF 352 HSP 2 Score: 82.4185 bits (202), Expect = 3.478e-16 Identity = 58/214 (27.10%), Postives = 109/214 (50.93%), Query Frame = 1
Query: 481 DNEDLFVVVDLLTGGDMRFHSNNQTLKFSEKTVKLYICEISLVLDYLQSKRIIHRDIKPDNLL-LDENG---HIHLTDFNVATELQSNKS--YSICGTKPYMAYEFFSDSLCNTGYSYEVDWWSLGIVAFELLVKKRPFKIQSNSSMNECRQIIENSKF-YSHRYSDFISGEMLDLIFSLLRLESEYRVSSLKQIQENLLMKDINWNQVAKKQI 1101
D + +++V++L+ GG++ Q FSE+ +C I+ ++YL S+ ++HRD+KP N+L +DE G I + DF A +L++ + C T ++A E L GY D WSLGI+ + +L PF + + E I + KF S D +S D++ +L ++ R+++ ++ + +N +Q+++ Q+
Sbjct: 478 DGKFVYLVMELMRGGELLDRILRQKC-FSEREASAVLCTITKTVEYLHSQGVVHRDLKPSNILYVDETGDPESIRICDFGFAKQLRAENGLLMTPCYTANFVAPEV----LKKQGYDAACDIWSLGILLYTMLAGFTPFANGPDDTPEEILARIGSGKFALSGGNWDTVSDAAKDIVTKMLHVDPHQRLTAPLVLRHAWI---VNRDQLSQSQL 683
BLAST of Serine/threonine kinase 32A vs. Ensembl Xenopus
Match: STK32B (serine/threonine kinase 32B [Source:NCBI gene;Acc:100495481]) HSP 1 Score: 278.485 bits (711), Expect = 1.546e-89 Identity = 149/314 (47.45%), Postives = 193/314 (61.46%), Query Frame = 1
Query: 256 NKVACIEKHAVSNVMREIRILLKLNHPFIVNLWYTFQDSNCQSMART*LFIIHLFQNESTINRQFVSHIGVKRTLDNEDLFVVVDLLTGGDMRFHSNNQTLKFSEKTVKLYICEISLVLDYLQSKRIIHRDIKPDNLLLDENGHIHLTDFNVATELQ-SNKSYSICGTKPYMAYEFFSDSL-CNTGYSYEVDWWSLGIVAFELLVKKRPFKIQSNSSMNECRQIIENSKFYSHRYSDFISGEMLDLIFSLLRLESEYRVSSLKQIQENLLMKDINWNQVAKKQIEPDFKPSSNHLNCDPTFELEEMIIESKPLH 1191
NK CIE+ V NV RE++I+ L HPF+VNLWY+FQD ED+F+VVDLL GGD+R+H Q + F+E+TVK+YICE+SL LDYLQ IIHRDIKPDN+LLDE+GH+H+TDFN+AT ++ S K+ S+ GTKPYMA E F L GYSY VDWWSLGI A+ELL RP++I S + +++ I+ K YS +M+ L+ LL + + R SSL +Q + + DINW+ V K + F P+ LNCDPTFELEEMI+ESKPLH
Sbjct: 8 NKQKCIERDEVRNVFRELQIMQCLEHPFLVNLWYSFQD--------------------------------------EEDMFMVVDLLLGGDLRYHLQ-QNVHFNEETVKIYICELSLALDYLQQHHIIHRDIKPDNILLDEHGHVHITDFNIATIVKGSEKASSMAGTKPYMAPEVFQSFLEAGPGYSYPVDWWSLGITAYELLRGWRPYEIHSTTPIDD---ILNMFKIERVHYSSTWGKDMVALLKKLLTKDPDCRYSSLSDMQSSPHLSDINWDAVLDKSLTASFVPNKGRLNCDPTFELEEMILESKPLH 279
BLAST of Serine/threonine kinase 32A vs. Ensembl Xenopus
Match: nek8 (NIMA-related kinase 8 [Source:Xenbase;Acc:XB-GENE-990378]) HSP 1 Score: 280.026 bits (715), Expect = 2.164e-89 Identity = 161/370 (43.51%), Postives = 222/370 (60.00%), Query Frame = 1
Query: 256 NKVACIEKHAVSNVMREIRILLKLNHPFIVNLWYTFQDSNCQSMART*LFIIHLFQNESTINRQFVSHIGVKRTLDNEDLFVVVDLLTGGDMRFHSNNQTLKFSEKTVKLYICEISLVLDYLQSKRIIHRDIKPDNLLLDENGHIHLTDFNVATELQSN-KSYSICGTKPYMAYEFFSDSL-CNTGYSYEVDWWSLGIVAFELLVKKRPFKIQSNSSMNECRQIIENSKFYSHRYSDFISGEMLDLIFSLLRLESEYRVSSLKQIQENLLMKDINWNQVAKKQIEPDFKPSSNHLNCDPTFELEEMIIESKPLH----KKEKRLAKQLKNNKNQMNSXXXXXXXXXXXXFTVFNRESFLKKEENEKNFNS 1347
NK CIE+ V NV RE+ IL ++ H F+VNLWY+FQD ED+F+VVDLL GGD+R+H Q ++F+E+TVK+YICE++L LDYL+S+ IIHRD+KPDN+LLDE GH HLTDFNVAT ++ ++ ++ GTKPYMA E F + TGY++EVDWWSLGI+AFELL RP+ I S+S + Q+ + +YS S +M L+ LL + E R SSL IQ + + D W + K++EP F P+ L+CDPTFELEEMI+ES+PLH + K ++ + +Q + L+E L+ L++EF +FNRE K N+NS
Sbjct: 65 NKQQCIERDEVRNVFRELEILQEIEHVFLVNLWYSFQDE--------------------------------------EDMFMVVDLLLGGDLRYHLQ-QNVQFTEETVKMYICEMALALDYLRSQHIIHRDVKPDNILLDEQGHTHLTDFNVATIIKDGERATALAGTKPYMAPEIFQSFVNGGTGYAFEVDWWSLGIMAFELLRGWRPYDIHSSSPVETLVQLFST---VTVQYSSVWSKDMTGLLRKLLTVNPENRCSSLLDIQNSSFLADTVWEDILDKKVEPGFVPNKGRLHCDPTFELEEMILESRPLHKKKKRLAKNKSRDNSKDSSQSDDYLQECLDALQQEFVIFNRE---KSASMANNWNS 389
BLAST of Serine/threonine kinase 32A vs. Ensembl Xenopus
Match: nek8 (NIMA-related kinase 8 [Source:Xenbase;Acc:XB-GENE-990378]) HSP 1 Score: 279.641 bits (714), Expect = 2.441e-89 Identity = 159/360 (44.17%), Postives = 219/360 (60.83%), Query Frame = 1
Query: 256 NKVACIEKHAVSNVMREIRILLKLNHPFIVNLWYTFQDSNCQSMART*LFIIHLFQNESTINRQFVSHIGVKRTLDNEDLFVVVDLLTGGDMRFHSNNQTLKFSEKTVKLYICEISLVLDYLQSKRIIHRDIKPDNLLLDENGHIHLTDFNVATELQ-SNKSYSICGTKPYMAYEFFSDSL-CNTGYSYEVDWWSLGIVAFELLVKKRPFKIQSNSSMNECRQIIENSKFYSHRYSDFISGEMLDLIFSLLRLESEYRVSSLKQIQENLLMKDINWNQVAKKQIEPDFKPSSNHLNCDPTFELEEMIIESKPLH----KKEKRLAKQLKNNKNQMNSXXXXXXXXXXXXFTVFNRESFLK 1317
NK CIE+ V NV RE+ IL ++ H F+VNLWY+FQD ED+F+VVDLL GGD+R+H Q ++F+E+TVK+YICE++L LDYL+S+ IIHRD+KPDN+LLDE GH HLTDFNVAT ++ ++ ++ GTKPYMA E F + TGY++EVDWWSLGI+AFELL RP+ I S+S + Q+ + +YS S +M L+ LL + E R SSL IQ + + D W + K++EP F P+ L+CDPTFELEEMI+ES+PLH + K ++ + +Q + L+E L+ L++EF +FNRE LK
Sbjct: 8 NKQQCIERDEVRNVFRELEILQEIEHVFLVNLWYSFQD--------------------------------------EEDMFMVVDLLLGGDLRYHLQ-QNVQFTEETVKMYICEMALALDYLRSQHIIHRDVKPDNILLDEQGHTHLTDFNVATIIKDGERATALAGTKPYMAPEIFQSFVNGGTGYAFEVDWWSLGIMAFELLRGWRPYDIHSSSPVETLVQLFST---VTVQYSSVWSKDMTGLLRKLLTVNPENRCSSLLDIQNSSFLADTVWEDILDKKVEPGFVPNKGRLHCDPTFELEEMILESRPLHKKKKRLAKNKSRDNSKDSSQSDDYLQECLDALQQEFVIFNREIPLK 325
BLAST of Serine/threonine kinase 32A vs. Ensembl Xenopus
Match: nek8 (NIMA-related kinase 8 [Source:Xenbase;Acc:XB-GENE-990378]) HSP 1 Score: 278.1 bits (710), Expect = 3.276e-89 Identity = 145/314 (46.18%), Postives = 194/314 (61.78%), Query Frame = 1
Query: 256 NKVACIEKHAVSNVMREIRILLKLNHPFIVNLWYTFQDSNCQSMART*LFIIHLFQNESTINRQFVSHIGVKRTLDNEDLFVVVDLLTGGDMRFHSNNQTLKFSEKTVKLYICEISLVLDYLQSKRIIHRDIKPDNLLLDENGHIHLTDFNVATELQ-SNKSYSICGTKPYMAYEFFSDSL-CNTGYSYEVDWWSLGIVAFELLVKKRPFKIQSNSSMNECRQIIENSKFYSHRYSDFISGEMLDLIFSLLRLESEYRVSSLKQIQENLLMKDINWNQVAKKQIEPDFKPSSNHLNCDPTFELEEMIIESKPLH 1191
NK CIE+ V NV RE+ IL ++ H F+VNLWY+FQD ED+F+VVDLL GGD+R+H Q ++F+E+TVK+YICE++L LDYL+S+ IIHRD+KPDN+LLDE GH HLTDFNVAT ++ ++ ++ GTKPYMA E F + TGY++EVDWWSLGI+AFELL RP+ I S+S + Q+ + +YS S +M L+ LL + E R SSL IQ + + D W + K++EP F P+ L+CDPTFELEEMI+ES+PLH
Sbjct: 41 NKQQCIERDEVRNVFRELEILQEIEHVFLVNLWYSFQD--------------------------------------EEDMFMVVDLLLGGDLRYHLQ-QNVQFTEETVKMYICEMALALDYLRSQHIIHRDVKPDNILLDEQGHTHLTDFNVATIIKDGERATALAGTKPYMAPEIFQSFVNGGTGYAFEVDWWSLGIMAFELLRGWRPYDIHSSSPVETLVQLFST---VTVQYSSVWSKDMTGLLRKLLTVNPENRCSSLLDIQNSSFLADTVWEDILDKKVEPGFVPNKGRLHCDPTFELEEMILESRPLH 312
BLAST of Serine/threonine kinase 32A vs. Ensembl Xenopus
Match: STK32A (serine/threonine kinase 32A [Source:NCBI gene;Acc:100490429]) HSP 1 Score: 279.641 bits (714), Expect = 3.496e-89 Identity = 161/350 (46.00%), Postives = 216/350 (61.71%), Query Frame = 1
Query: 166 FSDFEVLRAIXXXX-----XXXXXXXXXXXXXXXXNKVACIEKHAVSNVMREIRILLKLNHPFIVNLWYTFQDSNCQSMART*LFIIHLFQNESTINRQFVSHIGVKRTLDNEDLFVVVDLLTGGDMRFHSNNQTLKFSEKTVKLYICEISLVLDYLQSKRIIHRDIKPDNLLLDENGHIHLTDFNVATEL-QSNKSYSICGTKPYMAYEFF--SDSLCNTGYSYEVDWWSLGIVAFELLVKKRPFKIQSNSSMNECRQIIENSKFYSHRYSDFISGEMLDLIFSLLRLESEYRVSSLKQIQENLLMKDINWNQVAKKQIEPDFKPSSNHLNCDPTFELEEMIIESKPLH 1191
F+ FE+LRAIGKG +K KKM+AMKYMNK C+E++ V NV +E++I+ L HPF+VNLWY+FQD ED+F+VVDLL GGD+R+H Q ++F+E +VKLYICE++L LDYLQSK IIHRDIKPDN+LLDE GH+H+TDFN+AT + + K ++ GTKPYMA E F +C YS+ VDWWSLG+ A+ELL +RPF I S+++ + + + Y S E++ L+ LL E R S L+ IQ+ + D+NW+ +K++ P F P+ LNCDPTFELEEMI+ESKPLH
Sbjct: 14 FNHFEILRAIGKGSFGKVCIVQKNDTKKMYAMKYMNKQKCVERNEVRNVFKELQIMQGLEHPFLVNLWYSFQD--------------------------------------EEDMFMVVDLLLGGDLRYHLQ-QNVRFTEASVKLYICELALALDYLQSKSIIHRDIKPDNVLLDEQGHVHITDFNIATLVSKGTKITTVAGTKPYMAPEMFYPRGQIC---YSFGVDWWSLGVTAYELLRGRRPFHIHSSTAATDIVHVFHTATV---TYPPAWSEEIVSLLHKLLDRNPEERFSCLEHIQDFPYLSDVNWDAALQKRLSPQFIPTKGRLNCDPTFELEEMILESKPLH 318
BLAST of Serine/threonine kinase 32A vs. Ensembl Mouse
Match: Stk32a (serine/threonine kinase 32A [Source:MGI Symbol;Acc:MGI:2442403]) HSP 1 Score: 305.064 bits (780), Expect = 4.100e-99 Identity = 186/407 (45.70%), Postives = 256/407 (62.90%), Query Frame = 1
Query: 151 NCEISFSDFEVLRAIXXXX-----XXXXXXXXXXXXXXXXNKVACIEKHAVSNVMREIRILLKLNHPFIVNLWYTFQDSNCQSMART*LFIIHLFQNESTINRQFVSHIGVKRTLDNEDLFVVVDLLTGGDMRFHSNNQTLKFSEKTVKLYICEISLVLDYLQSKRIIHRDIKPDNLLLDENGHIHLTDFNVATEL-QSNKSYSICGTKPYMAYEFFSDSLCNTGYSYEVDWWSLGIVAFELLVKKRPFKIQSNSSMNECRQIIENSKFYSHRYSDFISGEMLDLIFSLLRLESEYRVSSLKQIQENLLMKDINWNQVAKKQIEPDFKPSSNHLNCDPTFELEEMIIESKPLHKKEKRLA---KQLKNNKNQMNSXXXXXXXXXXXXFTVFNRESFLKKEENEKNFN 1344
N +++F FE+LRAIGKG +K KKM+AMKYMNK C+E++ V NV +E++I+ L HPF+VNLWY+FQD ED+F+VVDLL GGD+R+H Q + F E TVKL+ICE+++ LDYLQS+RIIHRD+KPDN+LLDE+GH+H+TDFN+A L + + ++ GTKPYMA E F+ S TGYS+ VDWWSLG+ A+ELL +RP+ I+S++S E + E + Y S EM+ L+ LL + R S L IQ M D+NW+ V +K++ P F P+ LNCDPTFELEEMI+ESKPLHKK+KRLA K++K + + L+E L+ ++KEF +FNRE +K + N++ N
Sbjct: 15 NEDVNFDHFEILRAIGKGSFGKVCIVRKNDTKKMYAMKYMNKQKCVERNEVRNVFKELQIMQGLEHPFLVNLWYSFQDE--------------------------------------EDMFMVVDLLLGGDLRYHLQ-QNVHFQEDTVKLFICELAMALDYLQSQRIIHRDMKPDNILLDEHGHVHITDFNIAAMLPKETRITTVAGTKPYMAPEMFT-SRKETGYSFAVDWWSLGVTAYELLRGRRPYHIRSSTSSKEIVNMFETAIV---TYPSAWSQEMVSLLKKLLEPNPDQRFSHLTDIQNFPYMSDMNWDAVLQKRLIPGFIPTKGRLNCDPTFELEEMILESKPLHKKKKRLAKREKEMKKSDSSQTCLLQEHLDAVQKEFIIFNREK-VKSDFNQRQAN 377
BLAST of Serine/threonine kinase 32A vs. Ensembl Mouse
Match: Stk32b (serine/threonine kinase 32B [Source:MGI Symbol;Acc:MGI:1927552]) HSP 1 Score: 303.523 bits (776), Expect = 2.558e-98 Identity = 185/402 (46.02%), Postives = 251/402 (62.44%), Query Frame = 1
Query: 151 NCEISFSDFEVLRAIXXXX-----XXXXXXXXXXXXXXXXNKVACIEKHAVSNVMREIRILLKLNHPFIVNLWYTFQDSNCQSMART*LFIIHLFQNESTINRQFVSHIGVKRTLDNEDLFVVVDLLTGGDMRFHSNNQTLKFSEKTVKLYICEISLVLDYLQSKRIIHRDIKPDNLLLDENGHIHLTDFNVATELQ-SNKSYSICGTKPYMAYEFFSDSL-CNTGYSYEVDWWSLGIVAFELLVKKRPFKIQSNSSMNECRQIIENSKFYSHRYSDFISGEMLDLIFSLLRLESEYRVSSLKQIQENLLMKDINWNQVAKKQIEPDFKPSSNHLNCDPTFELEEMIIESKPLHKKEKRLAKQLKNNKNQ----MNSXXXXXXXXXXXXFTVFNRESFLKKE 1323
N E++F F++LRAIGKG +K+ KKM+AMKYMNK C+E+ V NV RE++I+ L HPF+VNLWY+FQD ED+F+VVDLL GGD+R+H Q + F+E TVKLYICE++L L+YLQ IIHRDIKPDN+LLDE+GH+H+TDFN+AT L+ S K+ S+ GTKPYMA E F + GYSY VDWWSLG+ A+ELL RP++I S + ++E + + + + YS M+ L+ LL + E R+SSL+ IQ + D+NW+ V +K + P F P+ LNCDPTFELEEMI+ESKPLHKK+KRLAK + + +N L++ LE + KEF +FNRE +++
Sbjct: 15 NEEVNFDHFQILRAIGKGSFGKVCIVQKRDTKKMYAMKYMNKQKCVERDEVRNVFRELQIMQGLEHPFLVNLWYSFQDE--------------------------------------EDMFMVVDLLLGGDLRYHLQ-QNVHFTEGTVKLYICELALALEYLQRYHIIHRDIKPDNILLDEHGHVHITDFNIATVLKGSEKASSMAGTKPYMAPEVFQVYVDGGPGYSYPVDWWSLGVTAYELLRGWRPYEIHSATPIDEILNMFKVERVH---YSSTWCEGMVSLLKKLLTKDPESRLSSLRDIQSMTYLADMNWDAVFEKALMPGFVPNKGRLNCDPTFELEEMILESKPLHKKKKRLAKHRSRDSTKDSCPLNGHLQQCLETVRKEFIIFNREKLRRQQ 374
BLAST of Serine/threonine kinase 32A vs. Ensembl Mouse
Match: Stk32c (serine/threonine kinase 32C [Source:MGI Symbol;Acc:MGI:2385336]) HSP 1 Score: 275.018 bits (702), Expect = 8.777e-88 Identity = 141/314 (44.90%), Postives = 198/314 (63.06%), Query Frame = 1
Query: 256 NKVACIEKHAVSNVMREIRILLKLNHPFIVNLWYTFQDSNCQSMART*LFIIHLFQNESTINRQFVSHIGVKRTLDNEDLFVVVDLLTGGDMRFHSNNQTLKFSEKTVKLYICEISLVLDYLQSKRIIHRDIKPDNLLLDENGHIHLTDFNVATELQSN-KSYSICGTKPYMAYEFFSDSL-CNTGYSYEVDWWSLGIVAFELLVKKRPFKIQSNSSMNECRQIIENSKFYSHRYSDFISGEMLDLIFSLLRLESEYRVSSLKQIQENLLMKDINWNQVAKKQIEPDFKPSSNHLNCDPTFELEEMIIESKPLH 1191
NK CIE+ V NV RE+ IL ++ H F+VNLWY+FQD ED+F+VVDLL GGD+R+H Q ++FSE TV+LYICE++L LDYL+S+ IIHRD+KPDN+LLDE GH HLTDFN+AT ++ ++ ++ GTKPYMA E F + TGYS+EVDWWS+G++A+ELL RP+ I S++++ Q+ S +Y S EM+ L+ LL + E+R SSL+ +Q + + W+ +++K++EP F P+ L+CDPTFELEEMI+ES+PLH
Sbjct: 8 NKQQCIERDEVRNVFRELEILQEIEHVFLVNLWYSFQD--------------------------------------EEDMFMVVDLLLGGDLRYHLQ-QNVQFSEDTVRLYICEMALALDYLRSQHIIHRDVKPDNILLDEQGHAHLTDFNIATIIKDGERATALAGTKPYMAPEIFHSFVNGGTGYSFEVDWWSVGVMAYELLRGWRPYDIHSSNAVESLVQLFST---VSVQYVPTWSKEMVALLRKLLTVNPEHRFSSLQDMQTAPSLAHVLWDDLSEKKVEPGFVPNKGRLHCDPTFELEEMILESRPLH 279
BLAST of Serine/threonine kinase 32A vs. Ensembl Mouse
Match: Stk32c (serine/threonine kinase 32C [Source:MGI Symbol;Acc:MGI:2385336]) HSP 1 Score: 275.018 bits (702), Expect = 8.777e-88 Identity = 141/314 (44.90%), Postives = 198/314 (63.06%), Query Frame = 1
Query: 256 NKVACIEKHAVSNVMREIRILLKLNHPFIVNLWYTFQDSNCQSMART*LFIIHLFQNESTINRQFVSHIGVKRTLDNEDLFVVVDLLTGGDMRFHSNNQTLKFSEKTVKLYICEISLVLDYLQSKRIIHRDIKPDNLLLDENGHIHLTDFNVATELQSN-KSYSICGTKPYMAYEFFSDSL-CNTGYSYEVDWWSLGIVAFELLVKKRPFKIQSNSSMNECRQIIENSKFYSHRYSDFISGEMLDLIFSLLRLESEYRVSSLKQIQENLLMKDINWNQVAKKQIEPDFKPSSNHLNCDPTFELEEMIIESKPLH 1191
NK CIE+ V NV RE+ IL ++ H F+VNLWY+FQD ED+F+VVDLL GGD+R+H Q ++FSE TV+LYICE++L LDYL+S+ IIHRD+KPDN+LLDE GH HLTDFN+AT ++ ++ ++ GTKPYMA E F + TGYS+EVDWWS+G++A+ELL RP+ I S++++ Q+ S +Y S EM+ L+ LL + E+R SSL+ +Q + + W+ +++K++EP F P+ L+CDPTFELEEMI+ES+PLH
Sbjct: 8 NKQQCIERDEVRNVFRELEILQEIEHVFLVNLWYSFQD--------------------------------------EEDMFMVVDLLLGGDLRYHLQ-QNVQFSEDTVRLYICEMALALDYLRSQHIIHRDVKPDNILLDEQGHAHLTDFNIATIIKDGERATALAGTKPYMAPEIFHSFVNGGTGYSFEVDWWSVGVMAYELLRGWRPYDIHSSNAVESLVQLFST---VSVQYVPTWSKEMVALLRKLLTVNPEHRFSSLQDMQTAPSLAHVLWDDLSEKKVEPGFVPNKGRLHCDPTFELEEMILESRPLH 279
BLAST of Serine/threonine kinase 32A vs. Ensembl Mouse
Match: Stk32c (serine/threonine kinase 32C [Source:MGI Symbol;Acc:MGI:2385336]) HSP 1 Score: 277.715 bits (709), Expect = 2.079e-87 Identity = 158/352 (44.89%), Postives = 224/352 (63.64%), Query Frame = 1
Query: 157 EISFSDFEVLRAIXXXX-----XXXXXXXXXXXXXXXXNKVACIEKHAVSNVMREIRILLKLNHPFIVNLWYTFQDSNCQSMART*LFIIHLFQNESTINRQFVSHIGVKRTLDNEDLFVVVDLLTGGDMRFHSNNQTLKFSEKTVKLYICEISLVLDYLQSKRIIHRDIKPDNLLLDENGHIHLTDFNVATELQSN-KSYSICGTKPYMAYEFFSDSL-CNTGYSYEVDWWSLGIVAFELLVKKRPFKIQSNSSMNECRQIIENSKFYSHRYSDFISGEMLDLIFSLLRLESEYRVSSLKQIQENLLMKDINWNQVAKKQIEPDFKPSSNHLNCDPTFELEEMIIESKPLH 1191
+++F F++LRAIGKG +K+ +KM+AMKYMNK CIE+ V NV RE+ IL ++ H F+VNLWY+FQD ED+F+VVDLL GGD+R+H Q ++FSE TV+LYICE++L LDYL+S+ IIHRD+KPDN+LLDE GH HLTDFN+AT ++ ++ ++ GTKPYMA E F + TGYS+EVDWWS+G++A+ELL RP+ I S++++ Q+ S +Y S EM+ L+ LL + E+R SSL+ +Q + + W+ +++K++EP F P+ L+CDPTFELEEMI+ES+PLH
Sbjct: 88 DVNFDHFQILRAIGKGSFGKVCIVQKRDTEKMYAMKYMNKQQCIERDEVRNVFRELEILQEIEHVFLVNLWYSFQD--------------------------------------EEDMFMVVDLLLGGDLRYHLQ-QNVQFSEDTVRLYICEMALALDYLRSQHIIHRDVKPDNILLDEQGHAHLTDFNIATIIKDGERATALAGTKPYMAPEIFHSFVNGGTGYSFEVDWWSVGVMAYELLRGWRPYDIHSSNAVESLVQLFST---VSVQYVPTWSKEMVALLRKLLTVNPEHRFSSLQDMQTAPSLAHVLWDDLSEKKVEPGFVPNKGRLHCDPTFELEEMILESRPLH 397
BLAST of Serine/threonine kinase 32A vs. UniProt/SwissProt
Match: sp|Q8BGW6|ST32A_MOUSE (Serine/threonine-protein kinase 32A OS=Mus musculus OX=10090 GN=Stk32a PE=2 SV=1) HSP 1 Score: 305.064 bits (780), Expect = 2.868e-98 Identity = 186/407 (45.70%), Postives = 256/407 (62.90%), Query Frame = 1
Query: 151 NCEISFSDFEVLRAIXXXX-----XXXXXXXXXXXXXXXXNKVACIEKHAVSNVMREIRILLKLNHPFIVNLWYTFQDSNCQSMART*LFIIHLFQNESTINRQFVSHIGVKRTLDNEDLFVVVDLLTGGDMRFHSNNQTLKFSEKTVKLYICEISLVLDYLQSKRIIHRDIKPDNLLLDENGHIHLTDFNVATEL-QSNKSYSICGTKPYMAYEFFSDSLCNTGYSYEVDWWSLGIVAFELLVKKRPFKIQSNSSMNECRQIIENSKFYSHRYSDFISGEMLDLIFSLLRLESEYRVSSLKQIQENLLMKDINWNQVAKKQIEPDFKPSSNHLNCDPTFELEEMIIESKPLHKKEKRLA---KQLKNNKNQMNSXXXXXXXXXXXXFTVFNRESFLKKEENEKNFN 1344
N +++F FE+LRAIGKG +K KKM+AMKYMNK C+E++ V NV +E++I+ L HPF+VNLWY+FQD ED+F+VVDLL GGD+R+H Q + F E TVKL+ICE+++ LDYLQS+RIIHRD+KPDN+LLDE+GH+H+TDFN+A L + + ++ GTKPYMA E F+ S TGYS+ VDWWSLG+ A+ELL +RP+ I+S++S E + E + Y S EM+ L+ LL + R S L IQ M D+NW+ V +K++ P F P+ LNCDPTFELEEMI+ESKPLHKK+KRLA K++K + + L+E L+ ++KEF +FNRE +K + N++ N
Sbjct: 15 NEDVNFDHFEILRAIGKGSFGKVCIVRKNDTKKMYAMKYMNKQKCVERNEVRNVFKELQIMQGLEHPFLVNLWYSFQDE--------------------------------------EDMFMVVDLLLGGDLRYHLQ-QNVHFQEDTVKLFICELAMALDYLQSQRIIHRDMKPDNILLDEHGHVHITDFNIAAMLPKETRITTVAGTKPYMAPEMFT-SRKETGYSFAVDWWSLGVTAYELLRGRRPYHIRSSTSSKEIVNMFETAIV---TYPSAWSQEMVSLLKKLLEPNPDQRFSHLTDIQNFPYMSDMNWDAVLQKRLIPGFIPTKGRLNCDPTFELEEMILESKPLHKKKKRLAKREKEMKKSDSSQTCLLQEHLDAVQKEFIIFNREK-VKSDFNQRQAN 377
BLAST of Serine/threonine kinase 32A vs. UniProt/SwissProt
Match: sp|Q9JJX8|ST32B_MOUSE (Serine/threonine-protein kinase 32B OS=Mus musculus OX=10090 GN=Stk32b PE=2 SV=2) HSP 1 Score: 303.523 bits (776), Expect = 1.789e-97 Identity = 185/402 (46.02%), Postives = 251/402 (62.44%), Query Frame = 1
Query: 151 NCEISFSDFEVLRAIXXXX-----XXXXXXXXXXXXXXXXNKVACIEKHAVSNVMREIRILLKLNHPFIVNLWYTFQDSNCQSMART*LFIIHLFQNESTINRQFVSHIGVKRTLDNEDLFVVVDLLTGGDMRFHSNNQTLKFSEKTVKLYICEISLVLDYLQSKRIIHRDIKPDNLLLDENGHIHLTDFNVATELQ-SNKSYSICGTKPYMAYEFFSDSL-CNTGYSYEVDWWSLGIVAFELLVKKRPFKIQSNSSMNECRQIIENSKFYSHRYSDFISGEMLDLIFSLLRLESEYRVSSLKQIQENLLMKDINWNQVAKKQIEPDFKPSSNHLNCDPTFELEEMIIESKPLHKKEKRLAKQLKNNKNQ----MNSXXXXXXXXXXXXFTVFNRESFLKKE 1323
N E++F F++LRAIGKG +K+ KKM+AMKYMNK C+E+ V NV RE++I+ L HPF+VNLWY+FQD ED+F+VVDLL GGD+R+H Q + F+E TVKLYICE++L L+YLQ IIHRDIKPDN+LLDE+GH+H+TDFN+AT L+ S K+ S+ GTKPYMA E F + GYSY VDWWSLG+ A+ELL RP++I S + ++E + + + + YS M+ L+ LL + E R+SSL+ IQ + D+NW+ V +K + P F P+ LNCDPTFELEEMI+ESKPLHKK+KRLAK + + +N L++ LE + KEF +FNRE +++
Sbjct: 15 NEEVNFDHFQILRAIGKGSFGKVCIVQKRDTKKMYAMKYMNKQKCVERDEVRNVFRELQIMQGLEHPFLVNLWYSFQDE--------------------------------------EDMFMVVDLLLGGDLRYHLQ-QNVHFTEGTVKLYICELALALEYLQRYHIIHRDIKPDNILLDEHGHVHITDFNIATVLKGSEKASSMAGTKPYMAPEVFQVYVDGGPGYSYPVDWWSLGVTAYELLRGWRPYEIHSATPIDEILNMFKVERVH---YSSTWCEGMVSLLKKLLTKDPESRLSSLRDIQSMTYLADMNWDAVFEKALMPGFVPNKGRLNCDPTFELEEMILESKPLHKKKKRLAKHRSRDSTKDSCPLNGHLQQCLETVRKEFIIFNREKLRRQQ 374
BLAST of Serine/threonine kinase 32A vs. UniProt/SwissProt
Match: sp|Q9NY57|ST32B_HUMAN (Serine/threonine-protein kinase 32B OS=Homo sapiens OX=9606 GN=STK32B PE=2 SV=1) HSP 1 Score: 301.597 bits (771), Expect = 1.092e-96 Identity = 185/402 (46.02%), Postives = 249/402 (61.94%), Query Frame = 1
Query: 151 NCEISFSDFEVLRAIXXXX-----XXXXXXXXXXXXXXXXNKVACIEKHAVSNVMREIRILLKLNHPFIVNLWYTFQDSNCQSMART*LFIIHLFQNESTINRQFVSHIGVKRTLDNEDLFVVVDLLTGGDMRFHSNNQTLKFSEKTVKLYICEISLVLDYLQSKRIIHRDIKPDNLLLDENGHIHLTDFNVATELQ-SNKSYSICGTKPYMAYEFFSDSL-CNTGYSYEVDWWSLGIVAFELLVKKRPFKIQSNSSMNECRQIIENSKFYSHRYSDFISGEMLDLIFSLLRLESEYRVSSLKQIQENLLMKDINWNQVAKKQIEPDFKPSSNHLNCDPTFELEEMIIESKPLHKKEKRLAKQLKNNKNQ----MNSXXXXXXXXXXXXFTVFNRESFLKKE 1323
N E++F F++LRAIGKG +K+ KKM+AMKYMNK CIE+ V NV RE++I+ L HPF+VNLWY+FQD ED+F+VVDLL GGD+R+H Q + F+E TVKLYICE++L L+YLQ IIHRDIKPDN+LLDE+GH+H+TDFN+AT ++ + ++ S+ GTKPYMA E F + GYSY VDWWSLGI A+ELL RP++I S + ++E + + + + YS M+ L+ LL + E RVSSL IQ + D+NW+ V KK + P F P+ LNCDPTFELEEMI+ESKPLHKK+KRLAK + + +N L+ LE + +EF +FNRE +++
Sbjct: 15 NEEVNFDHFQILRAIGKGSFGKVCIVQKRDTKKMYAMKYMNKQKCIERDEVRNVFRELQIMQGLEHPFLVNLWYSFQDE--------------------------------------EDMFMVVDLLLGGDLRYHLQ-QNVHFTEGTVKLYICELALALEYLQRYHIIHRDIKPDNILLDEHGHVHITDFNIATVVKGAERASSMAGTKPYMAPEVFQVYMDRGPGYSYPVDWWSLGITAYELLRGWRPYEIHSVTPIDEILNMFKVERVH---YSSTWCKGMVALLRKLLTKDPESRVSSLHDIQSVPYLADMNWDAVFKKALMPGFVPNKGRLNCDPTFELEEMILESKPLHKKKKRLAKNRSRDGTKDSCPLNGHLQHCLETVREEFIIFNREKLRRQQ 374
BLAST of Serine/threonine kinase 32A vs. UniProt/SwissProt
Match: sp|Q8WU08|ST32A_HUMAN (Serine/threonine-protein kinase 32A OS=Homo sapiens OX=9606 GN=STK32A PE=1 SV=2) HSP 1 Score: 282.337 bits (721), Expect = 1.659e-89 Identity = 164/353 (46.46%), Postives = 219/353 (62.04%), Query Frame = 1
Query: 151 NCEISFSDFEVLRAIXXXX-----XXXXXXXXXXXXXXXXNKVACIEKHAVSNVMREIRILLKLNHPFIVNLWYTFQDSNCQSMART*LFIIHLFQNESTINRQFVSHIGVKRTLDNEDLFVVVDLLTGGDMRFHSNNQTLKFSEKTVKLYICEISLVLDYLQSKRIIHRDIKPDNLLLDENGHIHLTDFNVATEL-QSNKSYSICGTKPYMAYEFFSDSLCNTGYSYEVDWWSLGIVAFELLVKKRPFKIQSNSSMNECRQIIENSKFYSHRYSDFISGEMLDLIFSLLRLESEYRVSSLKQIQENLLMKDINWNQVAKKQIEPDFKPSSNHLNCDPTFELEEMIIESKPLH 1191
N +++F FE+LRAIGKG +K KKM+AMKYMNK C+E++ V NV +E++I+ L HPF+VNLWY+FQD ED+F+VVDLL GGD+R+H Q + F E+TVKL+ICE+ + LDYLQ++RIIHRD+KPDN+LLDE+GH+H+TDFN+A L + + ++ GTKPYMA E FS S GYS+ VDWWSLG+ A+ELL +RP+ I+S++S E E + Y S EM+ L+ LL + R S L +Q M DINW+ V +K++ P F P+ LNCDPTFELEEMI+ESKPLH
Sbjct: 15 NEDVNFDHFEILRAIGKGSFGKVCIVQKNDTKKMYAMKYMNKQKCVERNEVRNVFKELQIMQGLEHPFLVNLWYSFQDE--------------------------------------EDMFMVVDLLLGGDLRYHLQ-QNVHFKEETVKLFICELVMALDYLQNQRIIHRDMKPDNILLDEHGHVHITDFNIAAMLPRETQITTMAGTKPYMAPEMFS-SRKGAGYSFAVDWWSLGVTAYELLRGRRPYHIRSSTSSKEIVHTFETTVV---TYPSAWSQEMVSLLKKLLEPNPDQRFSQLSDVQNFPYMNDINWDAVFQKRLIPGFIPNKGRLNCDPTFELEEMILESKPLH 324
BLAST of Serine/threonine kinase 32A vs. UniProt/SwissProt
Match: sp|Q86UX6|ST32C_HUMAN (Serine/threonine-protein kinase 32C OS=Homo sapiens OX=9606 GN=STK32C PE=1 SV=1) HSP 1 Score: 280.796 bits (717), Expect = 1.036e-87 Identity = 172/402 (42.79%), Postives = 254/402 (63.18%), Query Frame = 1
Query: 157 EISFSDFEVLRAIXXXX-----XXXXXXXXXXXXXXXXNKVACIEKHAVSNVMREIRILLKLNHPFIVNLWYTFQDSNCQSMART*LFIIHLFQNESTINRQFVSHIGVKRTLDNEDLFVVVDLLTGGDMRFHSNNQTLKFSEKTVKLYICEISLVLDYLQSKRIIHRDIKPDNLLLDENGHIHLTDFNVATELQSN-KSYSICGTKPYMAYEFFSDSL-CNTGYSYEVDWWSLGIVAFELLVKKRPFKIQSNSSMNECRQIIENSKFYSHRYSDFISGEMLDLIFSLLRLESEYRVSSLKQIQENLLMKDINWNQVAKKQIEPDFKPSSNHLNCDPTFELEEMIIESKPLHKKEKRLAKQL-----KNNKNQMNSXXXXXXXXXXXXFTVFNRESFLKKEE 1326
+++F F++LRAIGKG +K+ +KM+AMKYMNK CIE+ V NV RE+ IL ++ H F+VNLWY+FQD ED+F+VVDLL GGD+R+H Q ++FSE TV+LYICE++L LDYL+ + IIHRD+KPDN+LLDE GH HLTDFN+AT ++ ++ ++ GTKPYMA E F + TGYS+EVDWWS+G++A+ELL RP+ I S++++ Q+ S +Y S EM+ L+ LL + E+R+SSL+ +Q + + W+ +++K++EP F P+ L+CDPTFELEEMI+ES+PLHKK+KRLAK +++ N L++ L+ ++++F +FNRE + ++
Sbjct: 87 DVNFDHFQILRAIGKGSFGKVCIVQKRDTEKMYAMKYMNKQQCIERDEVRNVFRELEILQEIEHVFLVNLWYSFQD--------------------------------------EEDMFMVVDLLLGGDLRYHLQ-QNVQFSEDTVRLYICEMALALDYLRGQHIIHRDVKPDNILLDERGHAHLTDFNIATIIKDGERATALAGTKPYMAPEIFHSFVNGGTGYSFEVDWWSVGVMAYELLRGWRPYDIHSSNAVESLVQLFST---VSVQYVPTWSKEMVALLRKLLTVNPEHRLSSLQDVQAAPALAGVLWDHLSEKRVEPGFVPNKGRLHCDPTFELEEMILESRPLHKKKKRLAKNKSRDNSRDSSQSENDYLQDCLDAIQQDFVIFNREKLKRSQD 446
BLAST of Serine/threonine kinase 32A vs. TrEMBL
Match: A0A498MLF0 (Serine threonine-kinase 32B OS=Labeo rohita OX=84645 GN=ROHU_006818 PE=4 SV=1) HSP 1 Score: 323.168 bits (827), Expect = 3.595e-103 Identity = 179/364 (49.18%), Postives = 233/364 (64.01%), Query Frame = 1
Query: 157 EISFSDFEVLRAIXXXXXXXXXXXXXXXXXXXXNKVACIEKHAVSNVMREIRILLKLNHPFIVNLWYTFQDSNCQSMART*LFIIHLFQNESTINRQFVSHIGVKRTLDNEDLFVVVDLLTGGDMRFHSNNQTLKFSEKTVKLYICEISLVLDYLQSKRIIHRDIKPDNLLLDENGHIHLTDFNVATELQ-SNKSYSICGTKPYMAYEFFSDSL-CNTGYSYEVDWWSLGIVAFELLVKKRPFKIQSNSSMNECRQIIENSKFYSHRYSDFISGEMLDLIFSLLRLESEYRVSSLKQIQENLLMKDINWNQVAKKQIEPDFKPSSNHLNCDPTFELEEMIIESKPLHKKEKRLAKQLKNNKNQM 1242
++SF F++LRAIGKG FGKK+ +KM+AMKY NK CIE+ V NV+RE++++ +L HPF+VNLW++FQD EDLF+VVDLL GGD+RFH Q + F E+T+KLYICE++L LDYLQ IIHRDIKPDN+LLDE+GH+H+TDFNVAT L+ S + S+ GTKPYMA E F + GYSY VDWW+LG+ A+ELL RPF+I+S+++ E II R+S SG MLDLI SLL + R S L +Q + + D++W+ V +K + P F P LNCDPTFELEEMI+ES+PLHKK+KRLAK N +
Sbjct: 7 KVSFDHFQILRAIGKGSFGKKRDSRKMYAMKYTNKQKCIERDEVRNVLRELQVMQRLEHPFLVNLWFSFQD--------------------------------------EEDLFMVVDLLLGGDLRFHLQ-QNVGFKEQTIKLYICELALALDYLQRSHIIHRDIKPDNILLDEHGHVHITDFNVATVLKGSETASSMAGTKPYMAPEMFRSFVDGGAGYSYAVDWWALGVTAYELLHGSRPFEIRSSTAAAEVLHIIHGQHV---RFSSVCSGAMLDLIRSLLTRDPASRPSCLSDVQASPYLLDVDWDAVLQKSVPPGFVPHKGRLNCDPTFELEEMILESRPLHKKKKRLAKSRNKRSNPL 328
BLAST of Serine/threonine kinase 32A vs. TrEMBL
Match: R7U5W2 (Protein kinase domain-containing protein OS=Capitella teleta OX=283909 GN=CAPTEDRAFT_92464 PE=3 SV=1) HSP 1 Score: 312.768 bits (800), Expect = 1.619e-99 Identity = 183/371 (49.33%), Postives = 248/371 (66.85%), Query Frame = 1
Query: 157 EISFSDFEVLRAIXXXX-----XXXXXXXXXXXXXXXXNKVACIEKHAVSNVMREIRILLKLNHPFIVNLWYTFQDSNCQSMART*LFIIHLFQNESTINRQFVSHIGVKRTLDNEDLFVVVDLLTGGDMRFHSNNQTLKFSEKTVKLYICEISLVLDYLQSKRIIHRDIKPDNLLLDENGHIHLTDFNVATELQSNK-SYSICGTKPYMAYEFFSDSLCN-TGYSYEVDWWSLGIVAFELLVKKRPFKIQSNSSMNECRQIIENSKFYSHRYSDFISG--EMLDLIFSLLRLESEYRVSSLKQIQENLLMKDINWNQVAKKQIEPDFKPSSNHLNCDPTFELEEMIIESKPLHKKEKRLAKQLKNNKNQM 1242
E++F F++LRAIGKG +KK KKMFAMKYMNK CI+K A+ NV RE+ +L L+HPF+VNLW+TFQD +ED+F+VVDLL GGD+R+H Q +KF E VKLYICEI+L L+YLQ RI+HRDIKPDN+LLDENGH+H+TDFN+ATEL + + S+ GTKPYMA E F+ +L N GY+Y VDWWSLG+ +E+L KRP++I S ++ NE Q+ F SH S +S +M DL+ LL ++++ R+S+L+ ++ + + D++++QV QI+P F PS +HLNCDPT+ELEEMIIE+KPLHKK+KRLAKQ N++ Q+
Sbjct: 17 EVNFDHFQILRAIGKGSFGKVCIVQKKDTKKMFAMKYMNKNMCIKKDAIRNVFREVELLQNLDHPFLVNLWFTFQD--------------------------------------DEDMFMVVDLLLGGDLRYHIQ-QDVKFDEARVKLYICEIALALEYLQKNRIVHRDIKPDNILLDENGHVHITDFNIATELLDGQLATSLSGTKPYMAPEVFACALDNCVGYTYAVDWWSLGVCIYEMLRAKRPYEIHSATTANEVTQL-----FASHSVSYPLSWDEDMRDLLRQLLCVDAKNRISTLEGMKAHPFLSDVDFDQVLTLQIKPLFIPSKDHLNCDPTYELEEMIIEAKPLHKKKKRLAKQ--NSRKQV 341
BLAST of Serine/threonine kinase 32A vs. TrEMBL
Match: A0A437CMQ3 (Protein kinase domain-containing protein OS=Oryzias javanicus OX=123683 GN=OJAV_G00143020 PE=3 SV=1) HSP 1 Score: 311.997 bits (798), Expect = 2.077e-98 Identity = 188/398 (47.24%), Postives = 259/398 (65.08%), Query Frame = 1
Query: 142 TTNNCEISFSDFEVLRAIXXXX-----XXXXXXXXXXXXXXXXNKVACIEKHAVSNVMREIRILLKLNHPFIVNLWYTFQDSNCQSMART*LFIIHLFQNESTINRQFVSHIGVKRTLDNEDLFVVVDLLTGGDMRFHSNNQTLKFSEKTVKLYICEISLVLDYLQSKRIIHRDIKPDNLLLDENGHIHLTDFNVATELQSN-KSYSICGTKPYMAYEFF-SDSLCNTGYSYEVDWWSLGIVAFELLVKKRPFKIQSNSSMNECRQIIENSKFYSHRYSDFISGEMLDLIFSLLRLESEYRVSSLKQIQENLLMKDINWNQVAKKQIEPDFKPSSNHLNCDPTFELEEMIIESKPLHKKEKRLAKQLK---NNKNQMNSXXXXXXXXXXXXFTVFNRE 1305
+ N E++F F++LRAIGKG +KK KKM+AMKYMNK+ C+E++ V NV++E++I+ L HPF+VN WY+FQD ED+F+VVDLL GGD+R+H Q + FSE TVKLYICE++L L YL+SKRIIHRDIKPDN+LLDE+GH+HLTDFN+A ++ + K+ SI GTKPYMA E F S + GYS+ VDWWSLGI A+ELL +RP+ ++SN+ NE I++ Y S EM L+ LL ++ + RVS L ++Q+ M D+NW+ V KQ+ P F P+ LNCDPTFELEEMI+ESKPLHKK+KRLA++ + ++ + N +L++ L+N++++F VFNRE
Sbjct: 12 SDNTDEVNFDHFQILRAIGKGSFGKVCIVQKKDTKKMYAMKYMNKLKCVERNEVRNVLKELQIMQNLEHPFLVNFWYSFQDE--------------------------------------EDMFMVVDLLLGGDLRYHLQ-QNVHFSESTVKLYICELALALGYLRSKRIIHRDIKPDNILLDEHGHVHLTDFNIAAIVKEDLKATSIAGTKPYMAPELFQSFESSHPGYSFAVDWWSLGITAYELLRGQRPYVMKSNTPANE---ILQTFHKVHPSYPAAWSLEMKSLLRKLLCIDVQKRVSCLAELQDLDYMSDVNWDAVHDKQVPPGFIPNRRRLNCDPTFELEEMILESKPLHKKKKRLARKTREQGSDGSPQNGQLQQRLDNVQRDFIVFNRE 367
BLAST of Serine/threonine kinase 32A vs. TrEMBL
Match: A0A3Q3N655 (Serine/threonine kinase 32A OS=Mastacembelus armatus OX=205130 GN=STK32A PE=3 SV=1) HSP 1 Score: 309.686 bits (792), Expect = 5.012e-98 Identity = 186/398 (46.73%), Postives = 260/398 (65.33%), Query Frame = 1
Query: 142 TTNNCEISFSDFEVLRAIXXXX-----XXXXXXXXXXXXXXXXNKVACIEKHAVSNVMREIRILLKLNHPFIVNLWYTFQDSNCQSMART*LFIIHLFQNESTINRQFVSHIGVKRTLDNEDLFVVVDLLTGGDMRFHSNNQTLKFSEKTVKLYICEISLVLDYLQSKRIIHRDIKPDNLLLDENGHIHLTDFNVATELQSN-KSYSICGTKPYMAYEFF-SDSLCNTGYSYEVDWWSLGIVAFELLVKKRPFKIQSNSSMNECRQIIENSKFYSHRYSDFISGEMLDLIFSLLRLESEYRVSSLKQIQENLLMKDINWNQVAKKQIEPDFKPSSNHLNCDPTFELEEMIIESKPLHKKEKRLAKQLKN---NKNQMNSXXXXXXXXXXXXFTVFNRE 1305
T + E++F F++LRAIGKG +KK KKM+AMKYMNK+ C+E++ V NV++E++I+ L HPF+VN WY+FQD ED+F+VVDLL GGD+R+H Q + FSE TVKLYICE++L L YL++KRIIHRDIKPDN+LLDE+GH+HLTDFN+A ++ + K+ SI GTKPYMA E F S + GYS+ VDWWSLGI A+ELL +RP+ ++SN+ NE I++ Y S EM L+ LL ++++ R+S L ++Q+ M D+NW+ V KQ+ P F P+ LNCDPTFELEEMI+ESKPLHKK+KRLA++ ++ + + N +L++ L+N++++F VFNRE
Sbjct: 12 TDDTDEVNFDHFQILRAIGKGSFGKVCIVQKKDTKKMYAMKYMNKLKCVERNEVRNVLKELQIMQNLEHPFLVNFWYSFQDE--------------------------------------EDMFMVVDLLLGGDLRYHLQ-QNVHFSESTVKLYICELALALGYLRTKRIIHRDIKPDNILLDEHGHVHLTDFNIAAIVKDDLKATSIAGTKPYMAPELFQSFEGFHPGYSFSVDWWSLGITAYELLRGQRPYVMRSNTPANE---ILQTFHKVHPSYPAGWSVEMKSLLRKLLCIDAQKRISCLAELQDLDYMSDVNWDAVLSKQLPPGFIPNRRRLNCDPTFELEEMILESKPLHKKKKRLARKTRDQGSDGSPQNGQLQQRLDNVQRDFIVFNRE 367
BLAST of Serine/threonine kinase 32A vs. TrEMBL
Match: A0A3B3H9E8 (Protein kinase domain-containing protein OS=Oryzias latipes OX=8090 GN=stk32a PE=3 SV=1) HSP 1 Score: 311.227 bits (796), Expect = 5.031e-98 Identity = 194/431 (45.01%), Postives = 268/431 (62.18%), Query Frame = 1
Query: 82 LTIGCSMGTRVCNPKDQSENTTNNCEISFSDFEVLRAIXXXX-----XXXXXXXXXXXXXXXXNKVACIEKHAVSNVMREIRILLKLNHPFIVNLWYTFQDSNCQSMART*LFIIHLFQNESTINRQFVSHIGVKRTLDNEDLFVVVDLLTGGDMRFHSNNQTLKFSEKTVKLYICEISLVLDYLQSKRIIHRDIKPDNLLLDENGHIHLTDFNVATELQSN-KSYSICGTKPYMAYEFF-SDSLCNTGYSYEVDWWSLGIVAFELLVKKRPFKIQSNSSMNECRQIIENSKFYSHRYSDFISGEMLDLIFSLLRLESEYRVSSLKQIQENLLMKDINWNQVAKKQIEPDFKPSSNHLNCDPTFELEEMIIESKPLHKKEKRLAKQLK---NNKNQMNSXXXXXXXXXXXXFTVFNRESFLKKEENEKNFN 1344
+ +G S T V N D E++F F++LRAIGKG +KK KKM+AMKYMNK+ C+E++ V NV++E++I+ L HPF+VN WY+FQD ED+F+VVDLL GGD+R+H Q + FSE TVKLYICE++L L YL+SKRIIHRDIKPDN+LLDE+GH+HLTDFN+A ++ + K+ SI GTKPYMA E F S + GYS+ VDWWSLGI A+ELL +RP+ ++SN+ NE I++ Y S EM L+ L ++ + RVS L ++Q+ M D+NW+ V KQ+ P F P+ LNCDPTFELEEMI+ESKPLHKK+KRLA++ + ++ + N +L++ L+N++++F VFNRE K + F+
Sbjct: 1 MGLGQSTKTLVSNDTD---------EVNFDHFQILRAIGKGSFGKVCIVQKKDTKKMYAMKYMNKLKCVERNEVRNVLKELQIMQNLEHPFLVNFWYSFQDE--------------------------------------EDMFMVVDLLLGGDLRYHLQ-QNVHFSESTVKLYICELALALGYLRSKRIIHRDIKPDNILLDEHGHVHLTDFNIAAIVKEDLKATSIAGTKPYMAPELFQSFEGSHPGYSFAVDWWSLGITAYELLRGQRPYVMKSNTPANE---ILQTFHKVHPSYPAAWSLEMKSLLRKFLCIDVQKRVSCLAELQDLDYMTDVNWDAVHGKQVPPGFIPNRRRLNCDPTFELEEMILESKPLHKKKKRLARKTREQGSDGSPQNGQLQQRLDNVQRDFIVFNREKSRKAAVDTSEFS 380
BLAST of Serine/threonine kinase 32A vs. Ensembl Cavefish
Match: STK32B (serine/threonine kinase 32B [Source:HGNC Symbol;Acc:HGNC:14217]) HSP 1 Score: 278.87 bits (712), Expect = 1.938e-88 Identity = 158/363 (43.53%), Postives = 217/363 (59.78%), Query Frame = 1
Query: 256 NKVACIEKHAVSNVMREIRILLKLNHPFIVNLWYTFQDSNCQSMART*LFIIHLFQNESTINRQFVSHIGVKRTLDNEDLFVVVDLLTGGDMRFHSNNQTLKFSEKTVKLYICEISLVLDYLQSKRIIHRDIKPDNLLLDENGHIHLTDFNVATELQ-SNKSYSICGTKPYMAYEFFSDSL-CNTGYSYEVDWWSLGIVAFELLVKKRPFKIQSNSSMNECRQIIENSKFYSHRYSDFISGEMLDLIFSLLRLESEYRVSSLKQIQENLLMKDINWNQVAKKQIEPDFKPSSNHLNCDPTFELEEMIIESKPLHKKEKRLAKQLKNNKNQMNSXXXXXXXXXXXXFTVFNRESFLKKEENEKN 1338
NK CIE+ + NV RE+ +L +L H F+VNLWY+FQD ED+F+VVDLL GGD+R+H Q + F E+TVKLY+CE++L L YLQS IIHRDIKPDN+LLDE GH+H+TD NVAT L+ S K+ S+ GTKPYMA E F + GY Y VDWW+LGI AFELL RP+ I S++++++ I + RYS S + L+ LL + E R+SS+ + + D+NW+ V +K + P F P+ LNCDPTFELEEMI+ESKPLHKK+K + ++ L++ L+ + +EFT+FNRE K+ + ++N
Sbjct: 127 NKQKCIERDELRNVFRELHLLQELQHSFLVNLWYSFQD--------------------------------------EEDMFMVVDLLLGGDLRYHLQ-QNVHFKEETVKLYVCELALALHYLQSCHIIHRDIKPDNILLDEQGHVHITDLNVATVLKDSEKASSLAGTKPYMAPEMFQSFVDGGPGYWYPVDWWALGITAFELLRGWRPYDIHSSTTVDDVLNIFRGDRV---RYSSTWSKGIETLLRKLLTKDPESRLSSISDLHTLPYLADVNWDAVLEKAVPPGFTPNKGRLNCDPTFELEEMILESKPLHKKKK--RLAKNKTCSPLSPHLQQGLDAVSQEFTIFNREKLKKQGDKQQN 445
BLAST of Serine/threonine kinase 32A vs. Ensembl Cavefish
Match: STK32B (serine/threonine kinase 32B [Source:HGNC Symbol;Acc:HGNC:14217]) HSP 1 Score: 274.633 bits (701), Expect = 6.232e-88 Identity = 180/390 (46.15%), Postives = 237/390 (60.77%), Query Frame = 1
Query: 157 EISFSDFEVLRAIXXXX-----XXXXXXXXXXXXXXXXNKVACIEKHAVSNVMREIRILLKLNHPFIVNLWYTFQDSNCQSMART*LFIIHLFQNESTINRQFVSHIGVKRTLDNEDLFVVVDLLTGGDMRFHSNNQTLKFSEKTVKLYICEISLVLDYLQSKRIIHRDIKPDNLLLDENGHIHLTDFNVATELQ-SNKSYSICGTKPYMAYEFFSDSL-CNTGYSYEVDWWSLGIVAFELLVKKRPFKIQSNSSMNECRQIIENSKFYSHRYSDFISGEMLDLIFSLLRLESEYRVSSLKQIQENLLMKDINWNQVAKKQIEPDFKPSSNHLNCDPTFELEEMIIESKPLHKKEKRLAKQLKNNKNQMNSXXXXXXXXXXXXFTVFNRE 1305
+++F F++LRAIGKG +KK KKMFAMKYMNK CIE+ + NV RE+ +L +L H F+VNLWY+FQD ED+F+VVDLL GGD+R+H Q + F E+TVKLY+CE++L L YLQS IIHRDIKPDN+LLDE GH+H+TD NVAT L+ S K+ S+ GTKPYMA E F + GY Y VDWW+LGI AFELL RP+ I S++++++ I + RYS S + L+ LL + E R+SS+ + + D+NW+ V +K + P F P+ LNCDPTFELEEMI+ESKPLHKK+KRLAK + Q L+ + +EFT+FNRE
Sbjct: 17 DVNFDHFQILRAIGKGSFGKVCIVQKKDSKKMFAMKYMNKQKCIERDELRNVFRELHLLQELQHSFLVNLWYSFQD--------------------------------------EEDMFMVVDLLLGGDLRYHLQ-QNVHFKEETVKLYVCELALALHYLQSCHIIHRDIKPDNILLDEQGHVHITDLNVATVLKDSEKASSLAGTKPYMAPEMFQSFVDGGPGYWYPVDWWALGITAFELLRGWRPYDIHSSTTVDDVLNIFRGDRV---RYSSTWSKGIETLLRKLLTKDPESRLSSISDLHTLPYLADVNWDAVLEKAVPPGFTPNKGRLNCDPTFELEEMILESKPLHKKKKRLAKNKTCSPLQ-------GLDAVSQEFTIFNRE 357
BLAST of Serine/threonine kinase 32A vs. Ensembl Cavefish
Match: ENSAMXT00000016900.2 (pep primary_assembly:Astyanax_mexicanus-2.0:14:36243060:36308323:-1 gene:ENSAMXG00000016406.2 transcript:ENSAMXT00000016900.2 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 274.248 bits (700), Expect = 1.827e-87 Identity = 176/420 (41.90%), Postives = 251/420 (59.76%), Query Frame = 1
Query: 100 MGTRVCNPKDQSENTTNNCEISFSDFEVLRAIXXXX-----XXXXXXXXXXXXXXXXNKVACIEKHAVSNVMREIRILLKLNHPFIVNLWYTFQDSNCQSMART*LFIIHLFQNESTINRQFVSHIGVKRTLDNEDLFVVVDLLTGGDMRFHSNNQTLKFSEKTVKLYICEISLVLDYLQSKRIIHRDIKPDNLLLDENGHIHLTDFNVATELQSN-KSYSICGTKPYMAYEFFSD-SLCNTGYSYEVDWWSLGIVAFELLVKKRPFKIQSNSSMNECRQIIENSKFYSHRYSDFISGEMLDLIFSLLRLESEYRVSSLKQIQENLLMKDINWNQVAKKQIEPDFKPS-SNHLNCDPTFELEEMIIESKPLHKKEKRLAKQLKNNKNQ----MNSXXXXXXXXXXXXFTVFNRESFLKKE 1323
MG + SE+T E++F F++LRAIGKG +KK KKM+AMKYMNK+ C+E++ V NV +E++I+ L HPF+VN WY+FQD ED+F+VVDLL GGD+R+H Q + FSE TVKLYICE++L L YL++KRIIHR + +GH HLTDFN+A ++ + K+ SI GTKPYMA E F + GYS+ VDWWSLGI A+ELL +RP+ ++S++ +E Q Y Y S E+ L+ LL +E++ R+S ++Q+ + D+NW+ V KQ+ P F P+ LNCDPTFELEEMI+ESKPLHKK+KRLA++ + N N ++++ L+ ++++F +FNRE +L K+
Sbjct: 1 MGLGQSSRSSVSEDTE---EVNFDHFQILRAIGKGSFGKVCIVQKKDTKKMYAMKYMNKLKCVERNEVRNVFKELQIMQNLEHPFLVNFWYSFQD--------------------------------------EEDMFMVVDLLLGGDLRYHLQ-QNVHFSESTVKLYICELALALQYLRNKRIIHRPTVYCVISCLFSGHTHLTDFNIAAIVKDDLKATSIAGTKPYMAPELFQTFEGTHPGYSFSVDWWSLGITAYELLRGQRPYIMRSSTPTSEIMQAFHKGNPY---YPATWSAEIKSLLRKLLCIEAQKRLSCFSELQDMDYLSDVNWDAVLNKQVPPGFIPNVKGRLNCDPTFELEEMILESKPLHKKKKRLARKTRENGGSGGSPQNGQIQQRLDTVQRDFIIFNRERYLSKK 375
BLAST of Serine/threonine kinase 32A vs. Ensembl Cavefish
Match: STK32C (serine/threonine kinase 32C [Source:HGNC Symbol;Acc:HGNC:21332]) HSP 1 Score: 269.24 bits (687), Expect = 7.006e-86 Identity = 171/393 (43.51%), Postives = 240/393 (61.07%), Query Frame = 1
Query: 160 ISFSDFEVLRAIXXXX-----XXXXXXXXXXXXXXXXNKVACIEKHAVSNVMREIRILLKLNHPFIVNLWYTFQDSNCQSMART*LFIIHLFQNESTINRQFVSHIGVKRTLDNEDLFVVVDLLTGGDMRFHSNNQTLKFSEKTVKLYICEISLVLDYLQSKRIIHRDIKPDNLLLDENGHIHLTDFNVATELQ-SNKSYSICGTKPYMAYEFFSDSLC-NTGYSYEVDWWSLGIVAFELLVKKRPFKIQSNSSMNECRQIIENSKFYSHRYSDFISGEMLDLIFSLLRLESEYRVSSLKQIQENLLMKDINWNQVAKKQIEPDFKPSSNHLNCDPTFELEEMIIESKPLHKKEKRLAKQLK--NNKNQM--NSXXXXXXXXXXXXFTVFNRE 1305
++F F++LRAIGKG +K+ +KM+AMKYMNK CIE+ V NV RE+ IL + H F+VNLWY+FQD ED+F+VVDLL GGD+R+H Q ++F+E+ VK+Y+CE++L LDYLQS+ IIHRDIKPDN+LLDE GH HLTDFN+AT ++ ++ ++ GTKPYMA E F + TGY++EVDWWSLG+ FE+L RP+ I +++S+ Q+ S +Y +++ L+ LL + E+R S ++NW+ V +K+ E F P+ L+CDPTFELEEMI+ES+PLHKK+KRLAK N+K+ N L+E LE +++EF +FNRE
Sbjct: 16 VNFDHFQILRAIGKGSFGKVCIVQKRDTEKMYAMKYMNKQQCIERDEVRNVFRELEILQDIEHVFLVNLWYSFQDE--------------------------------------EDMFMVVDLLLGGDLRYHLQ-QNVQFTEEAVKVYLCEMTLALDYLQSQHIIHRDIKPDNILLDEQGHAHLTDFNIATIIKDGERATALAGTKPYMAPEIFQSFVSGGTGYAFEVDWWSLGVTIFEVLRGWRPYDIHASNSVESLLQLFST---VSVQYCSSWHKDLVSLLRKLLTVNPEHRFS------------NVNWDAVYEKKTEAGFVPNKGRLHCDPTFELEEMILESRPLHKKKKRLAKNRSRDNSKDSQSENDYLQECLEVVQQEFMIFNRE 354
BLAST of Serine/threonine kinase 32A vs. Ensembl Cavefish
Match: rps6ka3b (ribosomal protein S6 kinase, polypeptide 3b [Source:ZFIN;Acc:ZDB-GENE-070209-74]) HSP 1 Score: 151.369 bits (381), Expect = 3.682e-39 Identity = 93/297 (31.31%), Postives = 146/297 (49.16%), Query Frame = 1
Query: 313 ILLKLNHPFIVNLWYTFQDSNCQSMART*LFIIHLFQNESTINRQFVSHIGVKRTLDNEDLFVVVDLLTGGDMRFHSNNQTLKFSEKTVKLYICEISLVLDYLQSKRIIHRDIKPDNLLLDENGHIHLTDFNVATEL--QSNKSYSICGTKPYMAYEFFSDSLCNTGYSYEVDWWSLGIVAFELLVKKRPFKIQSNSSMNECRQIIENSKFYSHRYSDFISGEMLDLIFSLLRLESEYRVSS----LKQIQENLLMKDINWNQVAKKQIEPDFKPSSNHLNCDPTFELEEMIIESKP 1185
IL+++NHPFIV L Y FQ L++++D L GGD+ F ++ + F+E+ VK Y+ E++L LD+L II+RD+KP+N+LLDE GHI LTDF ++ E NK+YS CGT YMA E + G+++ DWWS G++ FE+L PF+ E +I +K F+S E L+ +L + R+ + +++I+ + I+WN++ +++I P FKP+S D TF + P
Sbjct: 5 ILVEVNHPFIVKLHYAFQTEG--------------------------------------KLYLILDFLRGGDL-FTRLSKEVMFTEEDVKFYLAELALALDHLHGLGIIYRDLKPENILLDEEGHIKLTDFGLSKESIDHENKAYSFCGTVEYMAPEVVN----RRGHTHSADWWSYGVLMFEMLTGTLPFQ---GKDRKETMTMILKAKL---GMPQFLSAEAQSLLRNLFKRNPSNRLGAGPDGVEEIKRHQFYASIDWNKLFRREIHPPFKPASG--RPDDTFYFDPEFTAKTP 250 HSP 2 Score: 81.6481 bits (200), Expect = 4.937e-16 Identity = 57/214 (26.64%), Postives = 109/214 (50.93%), Query Frame = 1
Query: 481 DNEDLFVVVDLLTGGDMRFHSNNQTLKFSEKTVKLYICEISLVLDYLQSKRIIHRDIKPDNLL-LDENGH---IHLTDFNVATELQSNKS--YSICGTKPYMAYEFFSDSLCNTGYSYEVDWWSLGIVAFELLVKKRPFKIQSNSSMNECRQIIENSKF-YSHRYSDFISGEMLDLIFSLLRLESEYRVSSLKQIQENLLMKDINWNQVAKKQI 1101
D +++V +LL GG++ Q FSE+ + I+ ++YL ++ ++HRD+KP N+L +DE+G+ I + DF A +L++ + C T ++A E L GY D WSLG++ + +L PF + E I + KF + Y + +S E DL+ +L ++ R+++ + ++ + ++ +Q+ K Q+
Sbjct: 368 DGRSVYLVTELLKGGELLDKILRQKF-FSEREASAVLFTITKTVEYLHAQGVVHRDLKPSNILYVDESGNPESIRICDFGFAKQLRAENGLLMTPCYTANFVAPEV----LKKQGYDAACDIWSLGVLLYTMLTGFTPFANGPEDTPEEILARIGSGKFSLTGGYWNSVSTEAKDLVSKMLHVDPHQRLTAAQVLRHPWI---VHKDQLPKYQL 573
BLAST of Serine/threonine kinase 32A vs. Ensembl Sea Lamprey
Match: stk32a (serine/threonine kinase 32A [Source:ZFIN;Acc:ZDB-GENE-091204-271]) HSP 1 Score: 189.889 bits (481), Expect = 4.042e-58 Identity = 97/211 (45.97%), Postives = 128/211 (60.66%), Query Frame = 1
Query: 256 NKVACIEKHAVSNVMREIRILLKLNHPFIVNLWYTFQDSNCQSMART*LFIIHLFQNESTINRQFVSHIGVKRTLDNEDLFVVVDLLTGGDMRFHSNNQTLKFSEKTVKLYICEISLVLDYLQSKRIIHRDIKPDNLLLDENGHIHLTDFNVATEL-QSNKSYSICGTKPYMAYEFFSDSLCNTG-YSYEVDWWSLGIVAFELLVKKRPFK 882
NK CIE+ V NV RE++I+ +L H F+VNLWY+FQD ED+F+VVDLL GGD+R+H Q+ +F E+ V+LY+CE+SL LDYLQ + IIHRDIKPDN+LLDE+GH H+TDFN+AT + + ++ S+ GTKPYMA E F + YS VDWWSLG+ A+ELL P +
Sbjct: 20 NKQVCIERDEVRNVFRELQIMQELEHTFLVNLWYSFQD--------------------------------------EEDMFMVVDLLLGGDLRYHLQ-QSTRFQEEAVRLYLCELSLALDYLQQRHIIHRDIKPDNILLDEHGHAHITDFNIATVVKEGEQASSMAGTKPYMAPEMFRSYVEGAPRYSSAVDWWSLGVTAYELLRGWWPVR 191
BLAST of Serine/threonine kinase 32A vs. Ensembl Sea Lamprey
Match: ENSPMAT00000004683.1 (pep scaffold:Pmarinus_7.0:GL488517:199:5283:1 gene:ENSPMAG00000004265.1 transcript:ENSPMAT00000004683.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 123.25 bits (308), Expect = 2.659e-33 Identity = 67/173 (38.73%), Postives = 102/173 (58.96%), Query Frame = 1
Query: 493 LFVVVDLLTGGDMRFHSNNQTLKFSEKTVKLYICEISLVLDYLQSKRIIHRDIKPDNLLLDENGHIHLTDFNVATEL--QSNKSYSICGTKPYMAYEFFSDSLCNTGYSYEVDWWSLGIVAFELLVKKRPFKIQSNSSMNECRQIIENSKFYSHRYSDFISGEMLDLIFSLLR 1005
L++++D L GGD+ F ++ + F+E+ VK Y+ E++L LD+L S II+RD+KP+N+LLDE+GHI LTDF ++ E K+YS CGT YMA E + G+++ DWWS G++ FE+L PF+ E +I +K F+SGE L+ L +
Sbjct: 8 LYLILDFLRGGDL-FTRLSKEVMFTEEDVKFYLAELALALDHLHSLGIIYRDLKPENILLDESGHIGLTDFGLSKESIDHEKKAYSFCGTVEYMAPEVVN----RKGHTHSADWWSFGVLMFEMLTGTLPFQ---GKDRKETMTMILKAKL---GMPQFLSGEAQSLLRMLFK 169
BLAST of Serine/threonine kinase 32A vs. Ensembl Sea Lamprey
Match: ENSPMAT00000001814.1 (pep scaffold:Pmarinus_7.0:GL481074:830:17391:1 gene:ENSPMAG00000001637.1 transcript:ENSPMAT00000001814.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 121.709 bits (304), Expect = 1.869e-31 Identity = 77/282 (27.30%), Postives = 139/282 (49.29%), Query Frame = 1
Query: 286 VSNVMREIRILLKLNHPFIVNLWYTFQDSNCQSMART*LFIIHLFQNESTINRQFVSHIGVKRTLDNEDLFVVVDLLTGGDMRFHSNNQTLKFSEKTVKLYICEISLVLDYLQSKRIIHRDIKPDNLLLDENGHIHLTDFNVATELQSNKSYSICGTKPYMAYEFFSDSLCNTGYSYEVDWWSLGIVAFELLVKKRPFKIQSNSSMNECRQIIENSKFYSHRYSDFISGEMLDLIFSLLRLESEYRVSSLK----QIQENLLMKDINWNQVAKKQIEPDFKP 1119
V + + E RIL ++ PF+V L Y+F+D N +L++V++ + GG+M F + +FSE + Y +I L +YL S +I+RD+KP+NLL+D+ G+I +TDF A ++ +++++CGT Y+A E + + GY+ VDWW+LG++ +E+ PF ++ QI E R+ S ++ DL+ +LL+++ R +LK I+ + +W + ++++E F P
Sbjct: 23 VEHTLNEKRILQAISFPFLVRLEYSFKD--------------------------------------NSNLYMVLEYVPGGEM-FSHLRRIGRFSEPHSRFYAAQIVLAFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVK-GRTWTLCGTPEYLAPEI----ILSKGYNKAVDWWALGVLIYEMAAGYPPF------FADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFSTTDWIAIYQRKVEAPFIP 254
BLAST of Serine/threonine kinase 32A vs. Ensembl Sea Lamprey
Match: PRKCD (protein kinase C delta [Source:HGNC Symbol;Acc:HGNC:9399]) HSP 1 Score: 125.176 bits (313), Expect = 3.040e-31 Identity = 81/282 (28.72%), Postives = 128/282 (45.39%), Query Frame = 1
Query: 286 VSNVMREIRILL-KLNHPFIVNLWYTFQDSNCQSMART*LFIIHLFQNESTINRQFVSHIGVKRTLDNEDLFVVVDLLTGGDMRFHSNNQT-LKFSEKTVKLYICEISLVLDYLQSKRIIHRDIKPDNLLLDENGHIHLTDFNVATE--LQSNKSYSICGTKPYMAYEFFSDSLCNTGYSYEVDWWSLGIVAFELLVKKRPFKIQSNSSMNECRQIIENSKFYSHRYSDFISGEMLDLIFSLLRLESEYRVSSLKQIQENLLMKDINWNQVAKKQIEPDFKP 1119
V M E R+LL HPF+ +L TFQ E LF V++ LTGGD+ FH ++ T + Y E+ L +L S II+RD+K DN+LLD GH+ + DF + E N + + CGT Y+A E L Y VDWWS+G++ +E+L+ + PF S +E + E K ++ Y ++S +++ L + R+ ++ I+ + K+I+W + ++I P FKP
Sbjct: 294 VECTMVEKRVLLMACEHPFLTHLCGTFQT--------------------------------------KEHLFFVMEFLTGGDLMFHIQDKGKFDLPTGTNRFYAAEVICGLQFLHSHNIIYRDLKLDNVLLDREGHVKIADFGMCKEHVGAGNLATTFCGTPDYIAPEI----LLGRAYGTSVDWWSMGVLIYEMLIGQSPF---YGSDEDE---LFEAIKGHTPHYPRWLSDSSRNILSCLFERDHTKRLGAVGDIRLHPFFKNIDWPSLEARKITPPFKP 527
BLAST of Serine/threonine kinase 32A vs. Ensembl Sea Lamprey
Match: PRKCD (protein kinase C delta [Source:HGNC Symbol;Acc:HGNC:9399]) HSP 1 Score: 119.398 bits (298), Expect = 5.823e-31 Identity = 68/213 (31.92%), Postives = 113/213 (53.05%), Query Frame = 1
Query: 487 EDLFVVVDLLTGGDMRFHSNNQTLKFSEKTVKLYICEISLVLDYLQSKRIIHRDIKPDNLLLDENGHIHLTDFNVATE--LQSNKSYSICGTKPYMAYEFFSDSLCNTGYSYEVDWWSLGIVAFELLVKKRPFKIQSNSSMNECRQIIENSKFYSHRYSDFISGEMLDLIFSLLRLESEYRVSSLKQIQENLLMKDINWNQVAKKQIEPDFKP 1119
E L V++ L GGD+ FH + +F Y EI L +L + II+RD+K DN+LLD++GH+ + DF + E + ++ + CGT Y+A E + Y+ VDWWS G++ +E+L+ + PF+ + E I S Y Y +I+ + D++ LL E R+ +I+++ + INW + K+++EP FKP
Sbjct: 61 EHLMFVMEYLNGGDLMFHIQVKG-RFEIDRATFYAAEIVSGLQFLHDQGIIYRDLKLDNILLDKDGHVKIADFGMCKENIVGDVRAGTFCGTPDYIAPEI----VIGQKYNCSVDWWSFGVLLYEMLIGQSPFRGDDEEELFES---IRTSVPY---YPRWITKDSRDILPLLLEREPMKRLGVTGEIRQHPFFRTINWEALEKRELEPPFKP 262
BLAST of Serine/threonine kinase 32A vs. Ensembl Yeast
Match: TPK2 (cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; partially redundant with Tpk1p and Tpk3p; localizes to P-bodies during stationary phase; relocalizes to the cytosol in response to hypoxia [Source:SGD;Acc:S000006124]) HSP 1 Score: 131.724 bits (330), Expect = 1.697e-34 Identity = 79/292 (27.05%), Postives = 141/292 (48.29%), Query Frame = 1
Query: 259 KVACIEKHAVSNVMREIRILLKLNHPFIVNLWYTFQDSNCQSMART*LFIIHLFQNESTINRQFVSHIGVKRTLDNEDLFVVVDLLTGGDMRFHSNNQTLKFSEKTVKLYICEISLVLDYLQSKRIIHRDIKPDNLLLDENGHIHLTDFNVATELQSNKSYSICGTKPYMAYEFFSDSLCNTGYSYEVDWWSLGIVAFELLVKKRPFKIQSNSSMNECRQIIENSKFYSHRYSDFISGEMLDLIFSLLRLESEYRVSSL----KQIQENLLMKDINWNQVAKKQIEPDFKPS 1122
K ++ V + E R+L + HPF++ +W TFQD+ ++F+V+D + GG++ F ++ +F K Y E+ L L+YL + II+RD+KP+N+LLD NGHI +TDF A E+Q+ ++++CGT Y+A E + Y+ VDWWSLG++ +E+L PF + M +I++ Y + +++DL+ L+ + R+ +L + I+ + ++ W ++ K IE ++P
Sbjct: 103 KQQVVKMKQVEHTNDERRMLKLVEHPFLIRMWGTFQDAR--------------------------------------NIFMVMDYIEGGEL-FSLLRKSQRFPNPVAKFYAAEVILALEYLHAHNIIYRDLKPENILLDRNGHIKITDFGFAKEVQT-VTWTLCGTPDYIAPEV----ITTKPYNKSVDWWSLGVLIYEMLAGYTPF--YDTTPMKTYEKILQGKVV----YPPYFHPDVVDLLSKLITADLTRRIGNLQSGSRDIKAHPWFSEVVWERLLAKDIETPYEPP 344
BLAST of Serine/threonine kinase 32A vs. Ensembl Yeast
Match: TPK3 (cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; partially redundant with Tpk1p and Tpk2p; localizes to P-bodies during stationary phase; TPK3 has a paralog, TPK1, that arose from the whole genome duplication [Source:SGD;Acc:S000001649]) HSP 1 Score: 129.798 bits (325), Expect = 1.222e-33 Identity = 93/330 (28.18%), Postives = 163/330 (49.39%), Query Frame = 1
Query: 163 SFSDFEVLRAIXXXXXXXXXXXXXXXXXXXXNKVACIEKHAVSNVMR------EIRILLKLNHPFIVNLWYTFQDSNCQSMART*LFIIHLFQNESTINRQFVSHIGVKRTLDNEDLFVVVDLLTGGDMRFHSNNQTLKFSEKTVKLYICEISLVLDYLQSKRIIHRDIKPDNLLLDENGHIHLTDFNVATELQSNKSYSICGTKPYMAYEFFSDSLCNTGYSYEVDWWSLGIVAFELLVKKRPFKIQSNSSMNECRQIIENSKFYSHRYSDFISGEMLDLIFSLLRLESEYRVSSLKQIQENL----LMKDINWNQVAKKQIEPDFKPS 1122
S SDF++LR +G G FG+ + ++ + ++KH + + + E R+L ++HPFI+ +W TFQDS + +F+V+D + GG++ F ++ +F K Y E+ L L+YL SK II+RD+KP+N+LLD+NGHI +TDF A + + +Y++CGT Y+A E S Y+ VDWWS G++ +E+L PF NS+ + + I N++ ++ F + DL+ L+ + R+ +L+ E++ ++ W ++ + IE ++P
Sbjct: 84 SLSDFQILRTLGTGSFGRVHLIRSNHNGRFY-ALKTLKKHTIVKLKQVEHTNDERRMLSIVSHPFIIRMWGTFQDS--------------------------------------QQVFMVMDYIEGGEL-FSLLRKSQRFPNPVAKFYAAEVCLALEYLHSKDIIYRDLKPENILLDKNGHIKITDFGFAKYV-PDVTYTLCGTPDYIAPEVVS----TKPYNKSVDWWSFGVLIYEMLAGYTPF---YNSNTMKTYENILNAEL---KFPPFFHPDAQDLLKKLITRDLSERLGNLQNGSEDVKNHPWFNEVIWEKLLARYIETPYEPP 362
BLAST of Serine/threonine kinase 32A vs. Ensembl Yeast
Match: SCH9 (AGC family protein kinase; functional ortholog of mammalian S6 kinase; phosphorylated by Tor1p and required for TORC1-mediated regulation of ribosome biogenesis, translation initiation, and entry into G0 phase; involved in transactivation of osmostress-responsive genes; regulates G1 progression, cAPK activity and nitrogen activation of the FGM pathway; integrates nutrient signals and stress signals from sphingolipids to regulate lifespan [Source:SGD;Acc:S000001248]) HSP 1 Score: 133.265 bits (334), Expect = 1.238e-33 Identity = 79/239 (33.05%), Postives = 132/239 (55.23%), Query Frame = 1
Query: 460 IGVKRTLDNE-DLFVVVDLLTGGDMRFHSNNQTLKFSEKTVKLYICEISLVLDYLQSKRIIHRDIKPDNLLLDENGHIHLTDFNVATELQSNKSYSICGTKPYMAYEFFSDSLCNTGYSYEVDWWSLGIVAFELLVKKRPFKIQSNSSMNECRQIIENSKFYSHRYSDFISGEMLDLIFSLLRLESEYRVSSL---KQIQENLLMKDINWNQVAKKQIEPDFKP----SSNHLNCDPTF 1152
+G+K + DL++V D ++GG++ +H + +FSE K YI E+ L L++L I++RD+KP+N+LLD NG+I L DF ++ +++ + CGT Y+A E D TGY+ VD+WSLG++ FE+ PF ++N M Q I K R D +S E + LL ++R+ ++ ++++ + DI+W + +K+I P FKP ++ N DP F
Sbjct: 476 VGLKFSFQTPTDLYLVTDYMSGGELFWHLQKEG-RFSEDRAKFYIAELVLALEHLHDNDIVYRDLKPENILLDANGNIALCDFGLSKADLKDRTNTFCGTTEYLAPELLLDE---TGYTKMVDFWSLGVLIFEMCCGWSPFFAENNQKM---YQKIAFGKVKFPR--DVLSQEGRSFVKGLLNRNPKHRLGAIDDGRELRAHPFFADIDWEALKQKKIPPPFKPHLVSETDTSNFDPEF 705
BLAST of Serine/threonine kinase 32A vs. Ensembl Yeast
Match: TPK1 (cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; inhibited by regulatory subunit Bcy1p in the absence of cAMP; phosphorylates and inhibits Whi3p to promote G1/S phase passage; partially redundant with Tpk2p and Tpk3p; phosphorylates pre-Tom40p, which impairs its import into mitochondria under non-respiratory conditions; TPK1 has a paralog, TPK3, that arose from the whole genome duplication [Source:SGD;Acc:S000003700]) HSP 1 Score: 129.028 bits (323), Expect = 1.767e-33 Identity = 80/283 (28.27%), Postives = 141/283 (49.82%), Query Frame = 1
Query: 310 RILLKL-NHPFIVNLWYTFQDSNCQSMART*LFIIHLFQNESTINRQFVSHIGVKRTLDNEDLFVVVDLLTGGDMRFHSNNQTLKFSEKTVKLYICEISLVLDYLQSKRIIHRDIKPDNLLLDENGHIHLTDFNVATELQSNKSYSICGTKPYMAYEFFSDSLCNTGYSYEVDWWSLGIVAFELLVKKRPFKIQSNSSMNECRQIIENSKFYSHRYSDFISGEMLDLIFSLLRLESEYRVSSLKQIQENL----LMKDINWNQVAKKQIEPDFKPSSNHLNCD 1143
R++L + HPFI+ +W TFQD+ + +F+++D + GG++ F ++ +F K Y E+ L L+YL SK II+RD+KP+N+LLD+NGHI +TDF A + + +Y++CGT Y+A E S Y+ +DWWS GI+ +E+L PF +S+ + + I N++ R+ F + ++ DL+ L+ + R+ +L+ E++ K++ W ++ + IE ++P D
Sbjct: 136 RLMLSIVTHPFIIRMWGTFQDA--------------------------------------QQIFMIMDYIEGGEL-FSLLRKSQRFPNPVAKFYAAEVCLALEYLHSKDIIYRDLKPENILLDKNGHIKITDFGFAKYV-PDVTYTLCGTPDYIAPEVVS----TKPYNKSIDWWSFGILIYEMLAGYTPF---YDSNTMKTYEKILNAEL---RFPPFFNEDVKDLLSRLITRDLSQRLGNLQNGTEDVKNHPWFKEVVWEKLLSRNIETPYEPPIQQGQGD 368
BLAST of Serine/threonine kinase 32A vs. Ensembl Yeast
Match: YPK2 (Protein kinase similar to S/T protein kinase Ypk1p; functionally redundant with YPK1 at the genetic level; participates in a signaling pathway required for optimal cell wall integrity; involved in the TORC-dependent phosphorylation of ribosomal proteins Rps6a/b (S6); human homolog SGK2 can complement a ypk1 ypk2 double mutant [Source:SGD;Acc:S000004710]) HSP 1 Score: 114.005 bits (284), Expect = 2.468e-27 Identity = 79/291 (27.15%), Postives = 136/291 (46.74%), Query Frame = 1
Query: 259 KVACIEKHAVSNVMREIRILLKLNHPFIVNLWYTFQDSNCQSMART*LFIIHLFQNESTINRQFVSHIGVKRTLDNEDLFVVVDLLTGGDMRFHSNNQTLKFSEKTVKLYICEISLVLDYLQSKRIIHRDIKPDNLLLDENGHIHLTDFNVAT-ELQSN-KSYSICGTKPYMAYEFFSDSLCNTGYSYEVDWWSLGIVAFELLVKKRPFKIQSNSSMNECRQIIENSKFYSHRYSDFISGEMLDLIFSLLRLESEYR--VSSLKQIQENLLMKDINWNQVAKKQIEPDFKP 1119
K + K V++ + E +L +++ PFIV L ++FQ E L++V+ + GG++ +H ++ +FS + YI E+ LD L +I+RD+KP+N+LLD GHI L DF + ++ N K+ + CGT Y+A E L GY+ VDWW+LGI+ +E++ P+ ++ M ++I++ + D DL+ LL + R V+ +I+ + KDI+W ++ K P +KP
Sbjct: 377 KAYIVSKCEVTHTLAERTVLARVDCPFIVPLKFSFQSP--------------------------------------EKLYLVLAFINGGELFYHLQHEG-RFSLARSRFYIAELLCALDSLHKLDVIYRDLKPENILLDYQGHIALCDFGLCKLNMKDNDKTDTFCGTPEYLAPEI----LLGQGYTKTVDWWTLGILLYEMMTGLPPYYDENVPVM--YKKILQQPLL----FPDGFDPAAKDLLIGLLSRDPSRRLGVNGTDEIRNHPFFKDISWKKLLLKGYIPPYKP 618
BLAST of Serine/threonine kinase 32A vs. Ensembl Nematostella
Match: EDO48735 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RIL6]) HSP 1 Score: 299.286 bits (765), Expect = 2.223e-97 Identity = 177/400 (44.25%), Postives = 251/400 (62.75%), Query Frame = 1
Query: 151 NCEISFSDFEVLRAIXXXX-----XXXXXXXXXXXXXXXXNKVACIEKHAVSNVMREIRILLKLNHPFIVNLWYTFQDSNCQSMART*LFIIHLFQNESTINRQFVSHIGVKRTLDNEDLFVVVDLLTGGDMRFHSNNQTLKFSEKTVKLYICEISLVLDYLQSKRIIHRDIKPDNLLLDENGHIHLTDFNVATELQSNK-SYSICGTKPYMAYEFFSDSLCN--TGYSYEVDWWSLGIVAFELLVKKRPFKIQSNSSMNE-CRQIIENSKFYSHRYSDFISGEMLDLIFSLLRLESEYRVSSLKQIQENLLMKDINWNQVAKKQIEPDFKPSSNHLNCDPTFELEEMIIESKPLHKKEKRLAKQLKNNKNQMNS-XXXXXXXXXXXXFTVFNRESFLKK 1320
N E+ F F++LRAIGKG +KK K M+AMKYMNK ACI+K AV NV+RE+ IL + HPFIVNLW++FQD ED+F+VVDLL GGD+R+H Q ++ E VKLYICE+ L L YL+SK+I+HRD+KPDN+LLDE GH+HLTDFN+AT LQ + S+ GTKPYMA E F + C GY + VDWW LG+ A+E+L +RP++I +N+S+ E C+ S Y +S+ M+ ++ LL+ + + R+ +++ ++E LM ++W V +K+++P F P +HLNCDPT+ELEEMIIESKPLHKK+KRLAK N+ ++ ++ +L+ + K F ++NRE L++
Sbjct: 15 NGEVCFDHFQILRAIGKGAFGKVCIVQKKDTKAMYAMKYMNKSACIKKDAVRNVLRELEILQTIEHPFIVNLWFSFQD--------------------------------------EEDIFMVVDLLLGGDIRYHLQ-QGMRVDENRVKLYICELGLALGYLRSKKIVHRDLKPDNMLLDEKGHVHLTDFNIATILQDGTLATSMSGTKPYMAPEIFH-TACGEKQGYGFAVDWWGLGLCAYEMLRLRRPYEILANTSIQEACQTFSSQSISYPCSWSE----PMVTILQKLLQQDPKSRLQTIEDLKEEHLMASVDWEMVYRKELKPSFVPPKDHLNCDPTYELEEMIIESKPLHKKKKRLAKMNSKIDNEASTDPMQVSLDEIRKTFKIYNREKCLQE 370
BLAST of Serine/threonine kinase 32A vs. Ensembl Nematostella
Match: EDO31895 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SWM6]) HSP 1 Score: 140.584 bits (353), Expect = 4.829e-36 Identity = 90/297 (30.30%), Postives = 147/297 (49.49%), Query Frame = 1
Query: 292 NVMREIRILLKLNHPFIVNLWYTFQDSNCQSMART*LFIIHLFQNESTINRQFVSHIGVKRTLDNEDLFVVVDLLTGGDMRFHSNNQTLKFSEKTVKLYICEISLVLDYLQSKRIIHRDIKPDNLLLDENGHIHLTDFNVATELQSN-KSYSICGTKPYMAYEFFSDSLCNTGYSYEVDWWSLGIVAFELLVKKRPFKIQSNS-SMNECRQIIENSKFYSHRYSDFISGEMLDLIFSLLRLESEYRVSS----LKQIQENLLMKDINWNQVAKKQIEPDFKPSSNHLN----CDPTF 1152
M+E IL+ + HPFIV L Y FQ +++++D L GGD+ F ++ + F+E+ VK Y+ E++L LD+L II+RD+KP+N+LLD +GH+ LTDF ++ E + + K+YS CGT YMA E + G+S DWWS G++ FE+L PF+ + +MN +I +K F++ E L+ L + R+ + ++ I+++ INW + K++I+P FKP++ + DP F
Sbjct: 55 RTMKERDILVDVQHPFIVRLNYAFQTEG--------------------------------------KVYLILDFLRGGDL-FTRLSKEIMFTEEDVKFYLAELALALDHLHGLGIIYRDLKPENILLDASGHVALTDFGLSKESEHDQKTYSFCGTVEYMAPEVVN----RRGHSQAADWWSYGVLMFEMLTGSLPFQGKDRKDTMN----MILKAKL---GMPQFLTPEAQSLLRQLFKRNPLNRLGAGDLGIEDIKKHPFFSTINWELLYKREIKPPFKPAAGRADDAFYFDPEF 301 HSP 2 Score: 56.9954 bits (136), Expect = 1.214e-8 Identity = 37/161 (22.98%), Postives = 80/161 (49.69%), Query Frame = 1
Query: 484 NEDLFVVVDLLTGGDMRFHSNNQTLK---FSEKTVKLYICEISLVLDYLQSKRIIHRDIKPDNLL-LDENG---HIHLTDFNVATELQSNKS--YSICGTKPYMAYEFFSDSLCNTGYSYEVDWWSLGIVAFELLVKKRPFKIQSNSSMNECRQIIENSKF 939
+ +++V++L+ GG++ ++ LK SE+ + ++ + +L + ++HRD+KP N++ D++G + + DF A ++++ + C T ++A E L GY D WSLG++ + +L PF + + + + I K+
Sbjct: 420 GKQVYIVMELMRGGELL----DRILKHKCLSEREAGNIMYTLTSTIAFLHEEGVVHRDLKPSNIMYADDSGTPESLRIVDFGFAKQMRATNGLLMTPCYTANFVAPEV----LKKQGYDAACDIWSLGVLLYTMLSGLTPFAVGPEDTPSVILKRIGEGKY 572
BLAST of Serine/threonine kinase 32A vs. Ensembl Nematostella
Match: EDO39163 (Ribosomal protein S6 kinase [Source:UniProtKB/TrEMBL;Acc:A7SAZ2]) HSP 1 Score: 134.806 bits (338), Expect = 1.024e-33 Identity = 77/217 (35.48%), Postives = 125/217 (57.60%), Query Frame = 1
Query: 493 LFVVVDLLTGGDMRFHSNNQTLKFSEKTVKLYICEISLVLDYLQSKRIIHRDIKPDNLLLDENGHIHLTDFNVATELQS----NKSYSICGTKPYMAYEFFSDSLCNTGYSYEVDWWSLGIVAFELLVKKRPFKI--QSNSSMNECRQIIENSKFYSHRYSDFISGEMLDLIFSLLRLESEYRVSS--LKQIQENLLMKDINWNQVAKKQIEPDFKP 1119
L +++D + GG++ F Q KF+E V+LYI EI + LD+L II+RDIK +N+LLD++GH+ LTDF ++ E + ++YS CGT YMA E + G+ VDWWSLG++ +ELL PF + + NS ++I+ N+ H +S E +DL+ LL+ + + R+ + +++ + K +W +A+K+I FKP
Sbjct: 94 LHLIMDYVNGGEL-FTHLYQREKFTEDEVRLYIGEIVVALDHLHQLGIIYRDIKLENILLDKDGHVVLTDFGLSKEFAAPNSGERAYSFCGTIEYMAPEVVKGG--SRGHDKAVDWWSLGVLMYELLTGASPFTVDGEKNSQSEISKRILHNNPPMPHD----LSAEAIDLLHKLLQKDPKKRLGAKGAHELKAHPFFKAFDWADLAEKRIPAPFKP 303 HSP 2 Score: 78.5666 bits (192), Expect = 2.311e-15 Identity = 50/187 (26.74%), Postives = 96/187 (51.34%), Query Frame = 1
Query: 496 FVVVDLLTGGDMRFHSNNQTLKFSEKTVKLYICEISLVLDYLQSKRIIHRDIKPDNLLL---DENGHIHLTDFNVA-TELQSNKSYSICGTKPYMAYEFFSDSLCNTGYSYEVDWWSLGIVAFELLVKKRPFKIQSN---SSMNECRQIIENS--KFYSHRYSDFISGEMLDLIFSLLRLESEYRVS 1029
++V++LL GG++ + + F+E + + +I ++++ + ++HRD+KP+NLL E+ I + DF A + ++ + + C T Y A E ++ N+GY D WSLG++ + +L + PF+ + SS Q I +F ++ IS + DLI LL ++ R++
Sbjct: 463 YLVMELLAGGELLERIRKKKM-FTESAASVIMRKIVSAVEFMHQRGVVHRDLKPENLLFVDNSEDAEIKIVDFGFACVKPEAQQLQTPCFTLSYAAPEVLDQTVSNSGYDESCDLWSLGVILYTMLSGQVPFQSSGSWYKSSTGFVMQRITQGDVRFDGQQWQS-ISPQAKDLIQGLLTVDPSQRLT 647
BLAST of Serine/threonine kinase 32A vs. Ensembl Nematostella
Match: EDO41166 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S521]) HSP 1 Score: 124.02 bits (310), Expect = 5.300e-31 Identity = 77/285 (27.02%), Postives = 135/285 (47.37%), Query Frame = 1
Query: 286 VSNVMREIRILLKLNHPFIVNLWYTFQDSNCQSMART*LFIIHLFQNESTINRQFVSHIGVKRTLDNEDLFVVVDLLTGGDMRFHSNNQTLKFSEKTVKLYICEISLVLDYLQSKRIIHRDIKPDNLLLDENGHIHLTDFNVATE--LQSNKSYSICGTKPYMAYEFFSDSLCNTGYSYEVDWWSLGIVAFELLVKKRPFKIQSNSSMNECRQIIENSKFYSHRYSDFISGEMLDLIFSLLRLESEYRVSSLK----QIQENLLMKDINWNQVAKKQIEPDFKPS 1122
++ E IL + HPFIV+L Y FQ L+++++ L+GG++ + + F E T Y+ EIS+ L++L + I++RD+KP+N+LLD NGH+ LTDF + E +++ +++ CGT YMA E L +G+ VDWWSLG + +++L PF +++ +I++ +++ E D I LL+ + R+ + I+ + + I W + K++EP F+PS
Sbjct: 111 TAHTKAERNILECVKHPFIVDLIYAFQTGG--------------------------------------KLYLILEYLSGGELFMQLEREGI-FLEDTACFYLSEISMALEHLHKQGIVYRDLKPENILLDANGHVKLTDFGLCKESIFENSLTHTFCGTIEYMAPEI----LTRSGHGKAVDWWSLGALMYDMLTGTPPF--CADNRKKTIDKILKGKLI----IPPYLTPEAKDFIRKLLKRHPQARLGGMAGDANPIKAHSFFRHICWEDLLAKKVEPPFRPS 346
BLAST of Serine/threonine kinase 32A vs. Ensembl Nematostella
Match: EDO35228 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SM62]) HSP 1 Score: 120.939 bits (302), Expect = 1.281e-30 Identity = 91/310 (29.35%), Postives = 151/310 (48.71%), Query Frame = 1
Query: 286 VSNVMREIRILLKLNHPFIVNLWYTFQDSNCQSMART*LFIIHLFQNESTINRQFVSHIGVKRTLDNEDLFVVVDLLTGGDMRFHSNNQTLKFSEKTVKLYICEISLVLDYLQSKRIIHRDIKPDNLLLDENGHIHLTDFNVATELQSNKSYSICGTKPYMAYEFFSDSLCNTGYSYEVDWWSLGIVAFELLVKKRPFKIQSNSSMNECRQIIENSKFYSHRYSDFISGEMLDLIFSLLRLESEYRVSSLKQIQENL----LMKDINWNQVAKKQIEPDFKPSSNHLNCDPTFE--LEEMIIESKPLHKK 1197
V +V E IL+ + HPFIVNL +T Q++ T L+++++ GG++ F +F+ T + EI +DYL I++RD+KP+N+LLD +GH+ LTDF A E+ +K++++CGT Y+A E + + G++ VDWW+LGI+ +E+LV PF + + E I + K ++ D S + DLI LL + R+ S+K E++ K I+WN V +++++P P +H F+ EE + PL+ K
Sbjct: 60 VEHVQNEKNILMSIEHPFIVNLLWT--------------------QHDQTF------------------LYMLLEYACGGEL-FTYLRTAGRFNNGTGLFFGSEIVSAMDYLHGHSIVYRDLKPENILLDRDGHVKLTDFGFAKEVH-DKTWTLCGTPEYLAPEI----IQSKGHNKAVDWWALGILIYEMLVGYPPFFDDNPFGIYEK---ILSGKVEWPKHMDNTSAK--DLIKKLLVHDRTRRLGSMKNGSEDVKNHKWFKVIDWNLVLQRKLKPPINPKISHPGDTRNFDDYPEEDWRGAPPLNAK 320
BLAST of Serine/threonine kinase 32A vs. Ensembl Medaka
Match: STK32A (serine/threonine kinase 32A [Source:NCBI gene;Acc:101167921]) HSP 1 Score: 311.227 bits (796), Expect = 1.894e-101 Identity = 194/431 (45.01%), Postives = 268/431 (62.18%), Query Frame = 1
Query: 82 LTIGCSMGTRVCNPKDQSENTTNNCEISFSDFEVLRAIXXXX-----XXXXXXXXXXXXXXXXNKVACIEKHAVSNVMREIRILLKLNHPFIVNLWYTFQDSNCQSMART*LFIIHLFQNESTINRQFVSHIGVKRTLDNEDLFVVVDLLTGGDMRFHSNNQTLKFSEKTVKLYICEISLVLDYLQSKRIIHRDIKPDNLLLDENGHIHLTDFNVATELQSN-KSYSICGTKPYMAYEFF-SDSLCNTGYSYEVDWWSLGIVAFELLVKKRPFKIQSNSSMNECRQIIENSKFYSHRYSDFISGEMLDLIFSLLRLESEYRVSSLKQIQENLLMKDINWNQVAKKQIEPDFKPSSNHLNCDPTFELEEMIIESKPLHKKEKRLAKQLK---NNKNQMNSXXXXXXXXXXXXFTVFNRESFLKKEENEKNFN 1344
+ +G S T V N D E++F F++LRAIGKG +KK KKM+AMKYMNK+ C+E++ V NV++E++I+ L HPF+VN WY+FQD ED+F+VVDLL GGD+R+H Q + FSE TVKLYICE++L L YL+SKRIIHRDIKPDN+LLDE+GH+HLTDFN+A ++ + K+ SI GTKPYMA E F S + GYS+ VDWWSLGI A+ELL +RP+ ++SN+ NE I++ Y S EM L+ L ++ + RVS L ++Q+ M D+NW+ V KQ+ P F P+ LNCDPTFELEEMI+ESKPLHKK+KRLA++ + ++ + N +L++ L+N++++F VFNRE K + F+
Sbjct: 1 MGLGQSTKTLVSNDTD---------EVNFDHFQILRAIGKGSFGKVCIVQKKDTKKMYAMKYMNKLKCVERNEVRNVLKELQIMQNLEHPFLVNFWYSFQDE--------------------------------------EDMFMVVDLLLGGDLRYHLQ-QNVHFSESTVKLYICELALALGYLRSKRIIHRDIKPDNILLDEHGHVHLTDFNIAAIVKEDLKATSIAGTKPYMAPELFQSFEGSHPGYSFAVDWWSLGITAYELLRGQRPYVMKSNTPANE---ILQTFHKVHPSYPAAWSLEMKSLLRKFLCIDVQKRVSCLAELQDLDYMTDVNWDAVHGKQVPPGFIPNRRRLNCDPTFELEEMILESKPLHKKKKRLARKTREQGSDGSPQNGQLQQRLDNVQRDFIVFNREKSRKAAVDTSEFS 380
BLAST of Serine/threonine kinase 32A vs. Ensembl Medaka
Match: STK32A (serine/threonine kinase 32A [Source:NCBI gene;Acc:101167921]) HSP 1 Score: 307.375 bits (786), Expect = 2.977e-100 Identity = 187/405 (46.17%), Postives = 259/405 (63.95%), Query Frame = 1
Query: 160 ISFSDFEVLRAIXXXX-----XXXXXXXXXXXXXXXXNKVACIEKHAVSNVMREIRILLKLNHPFIVNLWYTFQDSNCQSMART*LFIIHLFQNESTINRQFVSHIGVKRTLDNEDLFVVVDLLTGGDMRFHSNNQTLKFSEKTVKLYICEISLVLDYLQSKRIIHRDIKPDNLLLDENGHIHLTDFNVATELQSN-KSYSICGTKPYMAYEFF-SDSLCNTGYSYEVDWWSLGIVAFELLVKKRPFKIQSNSSMNECRQIIENSKFYSHRYSDFISGEMLDLIFSLLRLESEYRVSSLKQIQENLLMKDINWNQVAKKQIEPDFKPSSNHLNCDPTFELEEMIIESKPLHKKEKRLAKQLK---NNKNQMNSXXXXXXXXXXXXFTVFNRESFLKKEENEKNFN 1344
++F F++LRAIGKG +KK KKM+AMKYMNK+ C+E++ V NV++E++I+ L HPF+VN WY+FQD ED+F+VVDLL GGD+R+H Q + FSE TVKLYICE++L L YL+SKRIIHRDIKPDN+LLDE+GH+HLTDFN+A ++ + K+ SI GTKPYMA E F S + GYS+ VDWWSLGI A+ELL +RP+ ++SN+ NE I++ Y S EM L+ L ++ + RVS L ++Q+ M D+NW+ V KQ+ P F P+ LNCDPTFELEEMI+ESKPLHKK+KRLA++ + ++ + N +L++ L+N++++F VFNRE K + F+
Sbjct: 4 VNFDHFQILRAIGKGSFGKVCIVQKKDTKKMYAMKYMNKLKCVERNEVRNVLKELQIMQNLEHPFLVNFWYSFQDE--------------------------------------EDMFMVVDLLLGGDLRYHLQ-QNVHFSESTVKLYICELALALGYLRSKRIIHRDIKPDNILLDEHGHVHLTDFNIAAIVKEDLKATSIAGTKPYMAPELFQSFEGSHPGYSFAVDWWSLGITAYELLRGQRPYVMKSNTPANE---ILQTFHKVHPSYPAAWSLEMKSLLRKFLCIDVQKRVSCLAELQDLDYMTDVNWDAVHGKQVPPGFIPNRRRLNCDPTFELEEMILESKPLHKKKKRLARKTREQGSDGSPQNGQLQQRLDNVQRDFIVFNREKSRKAAVDTSEFS 366
BLAST of Serine/threonine kinase 32A vs. Ensembl Medaka
Match: STK32A (serine/threonine kinase 32A [Source:NCBI gene;Acc:101167921]) HSP 1 Score: 303.908 bits (777), Expect = 3.582e-99 Identity = 182/388 (46.91%), Postives = 243/388 (62.63%), Query Frame = 1
Query: 82 LTIGCSMGTRVCNPKDQSENTTNNCEISFSDFEVLRAIXXXX-----XXXXXXXXXXXXXXXXNKVACIEKHAVSNVMREIRILLKLNHPFIVNLWYTFQDSNCQSMART*LFIIHLFQNESTINRQFVSHIGVKRTLDNEDLFVVVDLLTGGDMRFHSNNQTLKFSEKTVKLYICEISLVLDYLQSKRIIHRDIKPDNLLLDENGHIHLTDFNVATELQSN-KSYSICGTKPYMAYEFF-SDSLCNTGYSYEVDWWSLGIVAFELLVKKRPFKIQSNSSMNECRQIIENSKFYSHRYSDFISGEMLDLIFSLLRLESEYRVSSLKQIQENLLMKDINWNQVAKKQIEPDFKPSSNHLNCDPTFELEEMIIESKPLHKKEKRLAKQLK 1224
+ +G S T V N D E++F F++LRAIGKG +KK KKM+AMKYMNK+ C+E++ V NV++E++I+ L HPF+VN WY+FQD ED+F+VVDLL GGD+R+H Q + FSE TVKLYICE++L L YL+SKRIIHRDIKPDN+LLDE+GH+HLTDFN+A ++ + K+ SI GTKPYMA E F S + GYS+ VDWWSLGI A+ELL +RP+ ++SN+ NE I++ Y S EM L+ L ++ + RVS L ++Q+ M D+NW+ V KQ+ P F P+ LNCDPTFELEEMI+ESKPLHKK+KRLA++ +
Sbjct: 1 MGLGQSTKTLVSNDTD---------EVNFDHFQILRAIGKGSFGKVCIVQKKDTKKMYAMKYMNKLKCVERNEVRNVLKELQIMQNLEHPFLVNFWYSFQDE--------------------------------------EDMFMVVDLLLGGDLRYHLQ-QNVHFSESTVKLYICELALALGYLRSKRIIHRDIKPDNILLDEHGHVHLTDFNIAAIVKEDLKATSIAGTKPYMAPELFQSFEGSHPGYSFAVDWWSLGITAYELLRGQRPYVMKSNTPANE---ILQTFHKVHPSYPAAWSLEMKSLLRKFLCIDVQKRVSCLAELQDLDYMTDVNWDAVHGKQVPPGFIPNRRRLNCDPTFELEEMILESKPLHKKKKRLARKTR 337
BLAST of Serine/threonine kinase 32A vs. Ensembl Medaka
Match: STK32C (serine/threonine kinase 32C [Source:NCBI gene;Acc:101155628]) HSP 1 Score: 269.626 bits (688), Expect = 2.576e-85 Identity = 173/401 (43.14%), Postives = 242/401 (60.35%), Query Frame = 1
Query: 160 ISFSDFEVLRAIXXXX-----XXXXXXXXXXXXXXXXNKVACIEKHAVSNVMREIRILLKLNHPFIVNLWYTFQDSNCQSMART*LFIIHLFQNESTINRQFVSHIGVKRTLDNEDLFVVVDLLTGGDMRFHSNNQTLKFSEKTVKLYICEISLVLDYLQSKRIIHRDIKPDNLLLDENGHIHLTDFNVATELQ-SNKSYSICGTKPYMAYEFFSDSLCN-TGYSYEVDWWSLGIVAFELLVKKRPFKIQSNSSMNECRQIIENSKFYSHRYSDFISGEMLDLIFSLLRLESEYRVSSLKQIQENLLMKDINWNQVAKKQIEPDFKPSSNHLNCDPTFELEEMIIESKPLHKKEKRLAKQLK--NNKNQM--NSXXXXXXXXXXXXFTVFNRESFLKKEEN 1329
I+F F++LRAIGKG +K+ +KM+AMKYMNK CIE+ V NV RE+ IL ++ H F+VNLWY+FQD ED+F+VVDLL GGD+R+H Q ++FSE VKLYICE++L LDYLQS+ IIHR +L+ GH HLTDFN+AT ++ ++ ++ GTKPYMA E F + +GY+ EVDWWSLG+ AFE+L RP+ I +++S+ Q+ S YS E++ L+ LL + ++R SSL +Q + + DINW+ V +K++ P F P+ L+CDPTFELEEMI+ES+PLHKK+KRLAK N+K+ N L+E LE +++EF +FN+ + LK E
Sbjct: 20 INFDHFQILRAIGKGSFGKVCIVQKRDTEKMYAMKYMNKQQCIERDEVRNVFRELEILQEIEHVFLVNLWYSFQD--------------------------------------EEDMFMVVDLLLGGDLRYHLQ-QNVQFSEAAVKLYICEMTLALDYLQSQHIIHRSFPSLWILVLSPGHAHLTDFNIATIVKDGERATALAGTKPYMAPEIFQSFISGGSGYALEVDWWSLGVTAFEVLRGWRPYDIHASNSVESLIQLFST---VSVHYSPSWPKELVSLLRKLLTVNPDHRFSSLSDMQASPYLADINWDAVYEKKMAPGFVPNKGRLHCDPTFELEEMILESRPLHKKKKRLAKNRSRDNSKDSQSENDYLQECLEAVQQEFMIFNQAALLKPSET 378
BLAST of Serine/threonine kinase 32A vs. Ensembl Medaka
Match: STK32C (serine/threonine kinase 32C [Source:NCBI gene;Acc:101155628]) HSP 1 Score: 267.7 bits (683), Expect = 7.449e-84 Identity = 161/371 (43.40%), Postives = 226/371 (60.92%), Query Frame = 1
Query: 157 EISFSDFEVLRAIXXXX-----XXXXXXXXXXXXXXXXNKVACIEKHAVSNVMREIRILLKLNHPFIVNLWYTFQDSNCQSMART*LFIIHLFQNESTINRQFVSHIGVKRTLDNEDLFVVVDLLTGGDMRFHSNNQTLKFSEKTVKLYICEISLVLDYLQSKRIIHRDIKPDNLLLDENGHIHLTDFNVATELQ-SNKSYSICGTKPYMAYEFFSDSLCN-TGYSYEVDWWSLGIVAFELLVKKRPFKIQSNSSMNECRQIIENSKFYSHRYSDFISGEMLDLIFSLLRLESEYRVSSLKQIQENLLMKDINWNQVAKKQIEPDFKPSSNHLNCDPTFELEEMIIESKPLHKKEKRLAKQLKNNKNQMNS 1248
+++F F++LRAIGKG +K+ +KM+AMKYMNK CIE+ V NV RE+ IL ++ H F+VNLWY+FQD ED+F+VVDLL GGD+R+H Q ++FSE VKLYICE++L LDYLQS+ IIHR +L+ GH HLTDFN+AT ++ ++ ++ GTKPYMA E F + +GY+ EVDWWSLG+ AFE+L RP+ I +++S+ Q+ S YS E++ L+ LL + ++R SSL +Q + + DINW+ V +K++ P F P+ L+CDPTFELEEMI+ES+PLHKK+KRLAK N+++ NS
Sbjct: 80 DVNFDHFQILRAIGKGSFGKVCIVQKRDTEKMYAMKYMNKQQCIERDEVRNVFRELEILQEIEHVFLVNLWYSFQD--------------------------------------EEDMFMVVDLLLGGDLRYHLQ-QNVQFSEAAVKLYICEMTLALDYLQSQHIIHRSFPSLWILVLSPGHAHLTDFNIATIVKDGERATALAGTKPYMAPEIFQSFISGGSGYALEVDWWSLGVTAFEVLRGWRPYDIHASNSVESLIQLFST---VSVHYSPSWPKELVSLLRKLLTVNPDHRFSSLSDMQASPYLADINWDAVYEKKMAPGFVPNKGRLHCDPTFELEEMILESRPLHKKKKRLAK----NRSRDNS 404
BLAST of Serine/threonine kinase 32A vs. Planmine SMEST
Match: SMESG000026303.1 (SMESG000026303.1) HSP 1 Score: 740.725 bits (1911), Expect = 0.000e+0 Identity = 401/426 (94.13%), Postives = 403/426 (94.60%), Query Frame = 1
Query: 100 MGTRVCNPKDQSENTTNNCEISFSDFEVLRAIXXXX-----XXXXXXXXXXXXXXXXNKVACIEKHAVSNVMREIRILLKLNHPFIVNLWYTFQDSNCQSMART*LFIIHLFQNESTINRQFVSHIGVKRTLDNEDLFVVVDLLTGGDMRFHSNNQTLKFSEKTVKLYICEISLVLDYLQSKRIIHRDIKPDNLLLDENGHIHLTDFNVATELQSNKSYSICGTKPYMAYEFFSDSLCNTGYSYEVDWWSLGIVAFELLVKKRPFKIQSNSSMNECRQIIENSKFYSHRYSDFISGEMLDLIFSLLRLESEYRVSSLKQIQENLLMKDINWNQVAKKQIEPDFKPSSNHLNCDPTFELEEMIIESKPLHKKEKRLAKQLKNNKNQMNSXXXXXXXXXXXXFTVFNRESFLKKEENEKNFNSTNFPN 1362
MGTRVCNPKDQSENTTN+CEISFSDFEVLRAIGKGG +KKFCKKMFAMKYMNKVACIEKHAVSNVMREIRILLKLNHPFIVNLWYTFQDSNCQSMART QFVSHIGVKRTLDNEDLFVVVDLLTGGDMRFHSNNQTLKFSEKTVKLYICEISLVLDYLQSKRIIHRDIKPDNLLLDENGHIHLTDFNVATELQSNKSYSICGTKPYMAYEFFSDSLCNTGYSYEVDWWSLGIVAFELLVKKRPFKIQSNSSMNECRQIIENSKFYSHRYSDFISGEMLDLIFSLLRLESEYRVSSLKQIQENLLMKDINWNQVAKKQIEPDFKPSSNHLNCDPTFELEEMIIESKPLHKKEKRLAKQLKNNKNQMNSELKEALENLEKEFTVFNRESFLKKEENEKNFNSTNFPN
Sbjct: 1 MGTRVCNPKDQSENTTNSCEISFSDFEVLRAIGKGGFGKVCIVQKKFCKKMFAMKYMNKVACIEKHAVSNVMREIRILLKLNHPFIVNLWYTFQDSNCQSMART----------------QFVSHIGVKRTLDNEDLFVVVDLLTGGDMRFHSNNQTLKFSEKTVKLYICEISLVLDYLQSKRIIHRDIKPDNLLLDENGHIHLTDFNVATELQSNKSYSICGTKPYMAYEFFSDSLCNTGYSYEVDWWSLGIVAFELLVKKRPFKIQSNSSMNECRQIIENSKFYSHRYSDFISGEMLDLIFSLLRLESEYRVSSLKQIQENLLMKDINWNQVAKKQIEPDFKPSSNHLNCDPTFELEEMIIESKPLHKKEKRLAKQLKNNKNQMNSELKEALENLEKEFTVFNRESFLKKEENEKNFNSTNFPN 410
BLAST of Serine/threonine kinase 32A vs. Planmine SMEST
Match: SMESG000026303.1 (SMESG000026303.1) HSP 1 Score: 685.256 bits (1767), Expect = 0.000e+0 Identity = 379/426 (88.97%), Postives = 381/426 (89.44%), Query Frame = 1
Query: 100 MGTRVCNPKDQSENTTNNCEISFSDFEVLRAIXXXX-----XXXXXXXXXXXXXXXXNKVACIEKHAVSNVMREIRILLKLNHPFIVNLWYTFQDSNCQSMART*LFIIHLFQNESTINRQFVSHIGVKRTLDNEDLFVVVDLLTGGDMRFHSNNQTLKFSEKTVKLYICEISLVLDYLQSKRIIHRDIKPDNLLLDENGHIHLTDFNVATELQSNKSYSICGTKPYMAYEFFSDSLCNTGYSYEVDWWSLGIVAFELLVKKRPFKIQSNSSMNECRQIIENSKFYSHRYSDFISGEMLDLIFSLLRLESEYRVSSLKQIQENLLMKDINWNQVAKKQIEPDFKPSSNHLNCDPTFELEEMIIESKPLHKKEKRLAKQLKNNKNQMNSXXXXXXXXXXXXFTVFNRESFLKKEENEKNFNSTNFPN 1362
MGTRVCNPKDQSENTTN+CEISFSDFEVLRAIGKGG +KKFCKKMFAMKYMNKVACIEKHAVSNVMREIRILLKLNHPFIVNLWYTFQD NEDLFVVVDLLTGGDMRFHSNNQTLKFSEKTVKLYICEISLVLDYLQSKRIIHRDIKPDNLLLDENGHIHLTDFNVATELQSNKSYSICGTKPYMAYEFFSDSLCNTGYSYEVDWWSLGIVAFELLVKKRPFKIQSNSSMNECRQIIENSKFYSHRYSDFISGEMLDLIFSLLRLESEYRVSSLKQIQENLLMKDINWNQVAKKQIEPDFKPSSNHLNCDPTFELEEMIIESKPLHKKEKRLAKQLKNNKNQMNSELKEALENLEKEFTVFNRESFLKKEENEKNFNSTNFPN
Sbjct: 1 MGTRVCNPKDQSENTTNSCEISFSDFEVLRAIGKGGFGKVCIVQKKFCKKMFAMKYMNKVACIEKHAVSNVMREIRILLKLNHPFIVNLWYTFQD--------------------------------------NEDLFVVVDLLTGGDMRFHSNNQTLKFSEKTVKLYICEISLVLDYLQSKRIIHRDIKPDNLLLDENGHIHLTDFNVATELQSNKSYSICGTKPYMAYEFFSDSLCNTGYSYEVDWWSLGIVAFELLVKKRPFKIQSNSSMNECRQIIENSKFYSHRYSDFISGEMLDLIFSLLRLESEYRVSSLKQIQENLLMKDINWNQVAKKQIEPDFKPSSNHLNCDPTFELEEMIIESKPLHKKEKRLAKQLKNNKNQMNSELKEALENLEKEFTVFNRESFLKKEENEKNFNSTNFPN 388
BLAST of Serine/threonine kinase 32A vs. Planmine SMEST
Match: SMESG000026303.1 (SMESG000026303.1) HSP 1 Score: 637.876 bits (1644), Expect = 0.000e+0 Identity = 361/426 (84.74%), Postives = 364/426 (85.45%), Query Frame = 1
Query: 100 MGTRVCNPKDQSENTTNNCEISFSDFEVLRAIXXXX-----XXXXXXXXXXXXXXXXNKVACIEKHAVSNVMREIRILLKLNHPFIVNLWYTFQDSNCQSMART*LFIIHLFQNESTINRQFVSHIGVKRTLDNEDLFVVVDLLTGGDMRFHSNNQTLKFSEKTVKLYICEISLVLDYLQSKRIIHRDIKPDNLLLDENGHIHLTDFNVATELQSNKSYSICGTKPYMAYEFFSDSLCNTGYSYEVDWWSLGIVAFELLVKKRPFKIQSNSSMNECRQIIENSKFYSHRYSDFISGEMLDLIFSLLRLESEYRVSSLKQIQENLLMKDINWNQVAKKQIEPDFKPSSNHLNCDPTFELEEMIIESKPLHKKEKRLAKQLKNNKNQMNSXXXXXXXXXXXXFTVFNRESFLKKEENEKNFNSTNFPN 1362
MGTRVCNPKDQSENTTN+CEISFSDFEVLRAIGKGG +KKFCKKMFAMKYMNKVACIEKHAVSNVMREIRILLKLNHPFIVNLWYTFQD NEDLFVVVDLLTGGDMRFHSNNQTLKFSEKTVKLYICEISLVLDYLQSKRIIHRDIKPDNLLLDENGHIHLTDFNVATELQSNKSYSICGTKPYMAYEFFSDSLCNTGYSYEVDWWSLGIVAFELLVKKRPFKIQSNSSMNECRQIIENSKFYSHRYSDFISGEMLDLIFSLLRLESEYRVSSLKQIQENLLMKDINWNQVAKKQIEPDFKPS +SKPLHKKEKRLAKQLKNNKNQMNSELKEALENLEKEFTVFNRESFLKKEENEKNFNSTNFPN
Sbjct: 1 MGTRVCNPKDQSENTTNSCEISFSDFEVLRAIGKGGFGKVCIVQKKFCKKMFAMKYMNKVACIEKHAVSNVMREIRILLKLNHPFIVNLWYTFQD--------------------------------------NEDLFVVVDLLTGGDMRFHSNNQTLKFSEKTVKLYICEISLVLDYLQSKRIIHRDIKPDNLLLDENGHIHLTDFNVATELQSNKSYSICGTKPYMAYEFFSDSLCNTGYSYEVDWWSLGIVAFELLVKKRPFKIQSNSSMNECRQIIENSKFYSHRYSDFISGEMLDLIFSLLRLESEYRVSSLKQIQENLLMKDINWNQVAKKQIEPDFKPS-----------------KSKPLHKKEKRLAKQLKNNKNQMNSELKEALENLEKEFTVFNRESFLKKEENEKNFNSTNFPN 371
BLAST of Serine/threonine kinase 32A vs. Planmine SMEST
Match: SMESG000026303.1 (SMESG000026303.1) HSP 1 Score: 152.91 bits (385), Expect = 1.010e-44 Identity = 95/104 (91.35%), Postives = 97/104 (93.27%), Query Frame = 1
Query: 100 MGTRVCNPKDQSENTTNNCEISFSDFEVLRAIXXXX-----XXXXXXXXXXXXXXXXNKVACIEKHAVSNVMREIRILLKLNHPFIVNLWYTFQDSNCQSMART 396
MGTRVCNPKDQSENTTN+CEISFSDFEVLRAIGKGG +KKFCKKMFAMKYMNKVACIEKHAVSNVMREIRILLKLNHPFIVNLWYTFQDSNCQSMART
Sbjct: 1 MGTRVCNPKDQSENTTNSCEISFSDFEVLRAIGKGGFGKVCIVQKKFCKKMFAMKYMNKVACIEKHAVSNVMREIRILLKLNHPFIVNLWYTFQDSNCQSMART 104
BLAST of Serine/threonine kinase 32A vs. Planmine SMEST
Match: SMESG000077752.1 (SMESG000077752.1) HSP 1 Score: 139.043 bits (349), Expect = 1.540e-36 Identity = 91/288 (31.60%), Postives = 147/288 (51.04%), Query Frame = 1
Query: 286 VSNVMREIRILLKLNHPFIVNLWYTFQDSNCQSMART*LFIIHLFQNESTINRQFVSHIGVKRTLDNEDLFVVVDLLTGGDMRFHSNNQTLKFSEKTVKLYICEISLVLDYLQSKRIIHRDIKPDNLLLDENGHIHLTDFNVATELQSNKSYSICGTKPYMAYEFFSDSLCNTGYSYEVDWWSLGIVAFELLVKKRPFKIQSNSSMNECRQIIENSKFYSHRYSDFISGEMLDLIFSLLRLESEYRVSSLKQIQENLL----MKDINWNQVAKKQIEPDFKPSSNHLN 1137
V +V+ E +IL +++HPFIV+L++T D L+++++ GG++ + N KF + T Y EI + YL RI++RD+KP+NLLLD+ GHI +TDF A L ++++Y++CGT Y+A E GY+ VDWW+LGI+ +E+L PF S+ + + Q I NSKF + D I+ DLI LL + R+ ++K E+++ K I+WN++ K++IEP P+ H+
Sbjct: 90 VEHVLSEKQILEQISHPFIVDLYWTKSDIKF--------------------------------------LYMLLEYACGGELFTYLRNMA-KFPDSTAMFYSAEIVSAISYLHGLRIVYRDLKPENLLLDQKGHIKITDFGFAKFL-TDRTYTMCGTPEYLAPEIIQ----GKGYNKAVDWWALGILIYEMLSGNPPF---SDDNPMQIYQKILNSKFEFPKQIDSIAK---DLIKKLLISDRMRRLGNMKGGSEDVMRHRWFKSIDWNELLKRKIEPPIIPNITHVG 327 The following BLAST results are available for this feature:
BLAST of Serine/threonine kinase 32A vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of Serine/threonine kinase 32A vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of Serine/threonine kinase 32A vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of Serine/threonine kinase 32A vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of Serine/threonine kinase 32A vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of Serine/threonine kinase 32A vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of Serine/threonine kinase 32A vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of Serine/threonine kinase 32A vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Serine/threonine kinase 32A vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of Serine/threonine kinase 32A vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 5
BLAST of Serine/threonine kinase 32A vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 5
BLAST of Serine/threonine kinase 32A vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of Serine/threonine kinase 32A vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of Serine/threonine kinase 32A vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30028559 ID=SMED30028559|Name=Serine/threonine kinase 32A|organism=Schmidtea mediterranea sexual|type=transcript|length=1497bpback to top protein sequence of SMED30028559-orf-1 >SMED30028559-orf-1 ID=SMED30028559-orf-1|Name=SMED30028559-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=279bp MRFHSNNQTLKFSEKTVKLYICEISLVLDYLQSKRIIHRDIKPDNLLLDEback to top protein sequence of SMED30028559-orf-2 >SMED30028559-orf-2 ID=SMED30028559-orf-2|Name=SMED30028559-orf-2|organism=Schmidtea mediterranea sexual|type=polypeptide|length=100bp MGTRVCNPKDQSENTTNNCEISFSDFEVLRAIGKGGFGKKKFCKKMFAMKback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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