zinc finger BED domain-containing protein 4-like

Query:  598 TSSIWNYFTVSPLINSKAICNLCNVSLSRGGNESKSFTTSNLVQHLRSKHVVAFADFXXXXXXXXXXXXXXXTASIPRPATIEA---LLDRRQPFEFNDKRALDWNKTIAEFMALDVQPFSVVDNVGFRRIIAKAEPRYTIPSSRYFSSTLIPAMHEKIQNKVREMVSSQPSTSL--TSDAWSDPSISVALLSLTAHWVT--------EDFQRKQAILAASPIEESHTGDYLGGMLLKILGDY-----TIEKSAVHVLLRDSGANMIKASRVADIDSISCFAHTLQLVINDSIMSQRSVKDILAISRSNVGKFRHSVLAQQHLSDLQGSLGVPKKKLVQDVQTRWNATLAMLRSLVEQKQVLGAYATEHKLTNL-DAHQWTLISHIIDTLSPFKDATKEVSDSQTSISVFLP-------------KHTMSEGIMTMRQDILTSLNKRFAHTKENRKMVLATILDPRFKNFAYDDRELASTAKQWLKNECLILASAERSEEVVEPPSKRPRVETDQAHPGSSTS---RLWDLFSDVVSEPALQTNSSIIGNVNDAVDAMIALYLSSAALPRTENPYVWWNSNKLLFPYLATLSRRYLSAPASSVPSEQLFSGAWQIFSDRRGSLTAGKGEMLLLLKYNLPQFSF 2421
            TS +WN+F++    ++K +C  C  ++SRG  +  +  TS L++HL+  H         +++  + A        +PR   +       D  + F  +   A      IAE +ALD+QP+S VDNVGF R++   +P+Y++P+  YFS T IP M++ ++  +   +    S  +  TS  W   + +   L+LTAHWV+         D     A+L  S ++     DY G  + K L  +     T     V + + D+ A++ K     +  S+ CF+HT+ L+++++I SQR V+++L+++R    +   S  A++ L++LQ    +P+  L+QDV ++W+ +  ML  L+EQK+ +   + E     L    QW ++  +   L PF+ A++E+S   +++S  +P             + TM  GI TM + +  ++  R + T  + + V AT+LDPR+K   + + E A   KQ L  E  ++ S   SE+V    S R     D   P   ++    LW L + V  +   +             +AM+  YL    L  + +P  +WN  K  +P L+ L+ R+L  P S VPSE+LF+   +  S  +  L     E L+ LK NLP   F
Sbjct:  560 TSKLWNHFSICSADSTKVVCLHCGRTISRG-KKPTNLGTSCLLRHLQRFHSNVL-----KTEVSETARPSSPDTRVPRGTELSGASSFDDTNEKFYDSHPVAKKITSLIAEMIALDLQPYSFVDNVGFNRLLEYLKPQYSLPAPSYFSRTAIPGMYDNVKQIIMSHLKEAESGVIHFTSGIWMS-NQTREYLTLTAHWVSFESPARPRCDDHHCSALLDVSQVD----CDYSGNSIQKQLECWWEAWVTSTGLQVGITVTDN-ASIGKTLNEGEHSSVQCFSHTVNLIVSEAIKSQRMVQNLLSLARKICERVHRSPKAKEKLAELQREYALPQHHLIQDVPSKWSTSFHMLERLIEQKRAINEMSVECNFRELISCDQWEVMQSVCRALKPFEAASREMSTQMSTLSQVIPMVHILNRKVEMLFEETM--GIDTMLRSLKEAMVSRLSATLHDPRYVFATLLDPRYKASLFTEEE-AEQYKQDLIRELELMNST--SEDVAA--SHR----CDAGSPSKDSAAEENLWSLVAKVKKKDPREK----------LPEAMVLAYLEEEVLEHSCDPLTYWNLKKASWPGLSALAVRFLGCPPSIVPSEKLFNTPTENGSLGQSRLMMEHFEKLIFLKVNLPLIYF 1169          

Query:  904 NKTIAEFMALDVQPFSVVDNVGFRRIIAKAEPRYTIPSSRYFSSTLIPAMHEKIQNKV---REMVSSQPSTSLTSDAWS-DPSISVALLSLTAHWVT------------EDFQRKQAILAASPIEESHTGDYLGGMLLKILGDYTIEKSAVHVLL-----RDSGANMIKASRVADIDSISCFAHTLQLVINDSIMSQRSVKDILAISRSNVGKFRHSVLAQQHLSDLQGSLGVPKKKLVQDVQTRWNATLAMLRSLVEQKQVLGAYATEHKLTN-----LDAHQWTLISHIIDTLSPFKDATKEVSDSQTSISVFLPK-HTMSEGIMTMRQD-----ILTSLN------------KRFAHTKENRKMVLATILDPRFKNFAYD------DRELASTAKQWLKNECLILASAERSEEVVEPPSKRPRVETDQAHPGSSTSRLWD-------LFSDVVSEPALQTNSSIIGNVNDAVDAMIALYLSSAALPRTENPYVWWNSNKLLFPYLATLSRRYLSAPASSVPSEQLFSGAWQIFSDRRGSLTAGKGEMLLLLKYNLPQFSFN 2424
            ++ I + +  D+ P++      F+R +    P Y +PS  YF +  +P +++ ++ K+    E V SQ    LT D W+ DPS    ++  T HWV+             DF RK A+L  + + +    D L   +L+ L D      + + L+      D+ +N++ A +      + CF H L +VI D     +S++++L  +R     F HSV A+Q L + Q    +P K L QD    W +T  ML+ L+E       Y+  H L       L + QWTL++++ D L PF++AT++VS     ++  LP  H +   +  +R+D     I  +LN               +   +++  +LAT+LDP FKN   D      D E   T KQ+L  E  +    E S E+ + P+      +      S TS L +       + S  V   AL + S +  +    VD       S       ++P ++W     ++P L  ++ +YLS P  S  SE +F+        +  SL     E L+ LK NL   +++
Sbjct:  411 SQAIIQMIVEDMHPYNYFSTPAFQRFMQIVAPDYRLPSETYFFTKAVPQLYDCVREKIFLTLENVQSQ-KIHLTVDIWTHDPSTDYFIV--TVHWVSLETASFLNNGRIPDF-RKWAVLCVTGLAK----DCLITNILQELNDQIGLWLSPNFLIPSFIVSDNSSNVVHAIKDGGFTHVPCFLHCLNMVIQDFFCEHKSIENMLVAARKTCHHFSHSVKARQILQEFQNDHQLPWKNLKQDETGHWISTFYMLKWLLEH-----CYSVHHSLGRASGVVLTSLQWTLMTYVCDILKPFEEATQKVSVKTAGLNQVLPLIHHLLLSLQKLREDFQVRGITQALNLVDSLSLKLETDTLLSAMLKSKPCILATLLDPCFKNSLEDFFPQGADLE---TYKQFLAEE--VCNYMESSPEICQIPTSEASCPSVTVGADSFTSSLKEGTSSSGSVDSSAVDNVALGSKSFMFPSAVAVVDEYFKEKYSE--FSGGDDPLIYWQRKISIWPALTQVAIQYLSCPMCSWQSECIFTKNSHFHPKQIMSLDFDNIEQLMFLKMNLKNVNYD 954          

Query:  601 SSIWNYFTVSP------LINSKAICNLCNVSLSRGGNESKSFTTSNLVQHLRSKHVVAFADFXXXXXXXXXXXXXXXTASIPRPATIEALLDR---RQPFEFNDKRALDWNKTIAEFMALDVQPFSVVDNVGFRRIIAKAEPRYTIPSSRYFSSTLIPAMHEKIQNKVREMVSSQPSTSLTSDAWSDPSISVALLSLTAHWVT----EDFQRKQAILAASPIEESHTGDYLGGMLLKILGDYTIEKSAVHVLLRDSGANMIKASRVADID-SISCFAHTLQLVINDSIMSQRSVKDILAISRSNVGKFRHSVLAQQHLSDLQGSLGVPKKKLVQDVQTRWNATLAMLRSLVEQKQVLGAYATE----HKLTNLDAHQWTLISHIIDTLSPFKDATKEVSDSQ-TSISVFLP------------KHTMSEGIMTMRQDILTSLNKRFAHTKE-NRKMVLATILDPRFKNFAYDDRELASTAKQWLKNECLILASAERSEEVVEPPSKRPRVETDQAHPGSSTSRLWDLFSDVVSEPALQTNSSI------IGNVND------AVDAMIALYLSSAALPRTENPYVWWNSNKLLFPYLATLSRRYLSAPASSVPSEQLFSGAWQIFSDRRGSL 2361
            S +W YF          L   K  C +C   ++  GN      TSNL  HL   H   F +F K + E+       + + +   ++ +   D    +    ++ K+  +    +   +   + P S+VD   F+ ++  A+PRY +PS +Y S+  IP  +  ++  + + ++      +++D W   + + A ++L AH++              L    + E +T + +  +L ++  ++ I  + V     + G +++KA  + D+   + C  HT    I  +    + +  +L+  R  V  F+ S +A   L + Q    V    LV +  + W +TLAML+ L EQ+ V+     E    H L  L+A +W  I  +++ L PFK   + +S S+  +IS+  P            K T S+ +   ++ I   L+K +  T E +  + +AT LDPR+K   +    L++  +Q ++N   ++  A+   + V+    RP    D+  P      +  L       PA   N+ +       G V D       V   ++ + S   L   E+P  WW+    LFP L  + ++Y    A+ V  E+LF  A  + S +R  L
Sbjct:   23 SKVWKYFGFDTNAEGCILQWKKIYCRICMAQIAYSGN------TSNLSYHLEKNHPEEFCEFVKSNTEQMREAFATAFSKLKPESSQQPGQDALAVKAGHGYDSKKQQELTAAVLGLICEGLYPASIVDEPTFKVLLKTADPRYELPSRKYISTKAIPEKYGAVREVILKELAEATWCGISTDMWRSENQNRAYVTLAAHFLGLGAPNCLSMGSRCLKTFEVPEENTAETITRVLYEVFIEWGI-SAKVFGATTNYGKDIVKACSLLDVAVHMPCLGHTFNAGIQQAFQLPK-LGALLSRCRKLVEYFQQSAVAMYMLYEKQKQQNVAHCMLVSNRVSWWGSTLAMLQRLKEQQFVIAGVLVEDSNNHHLM-LEASEWATIEGLVELLQPFKQVAEMLSASRYPTISMVKPLLHMLLNTTLNIKETDSKELSMAKEVIAKELSKTYQETPEIDMFLNVATFLDPRYKRLPF----LSAFERQQVENR--VVEEAKGLLDKVKDGGYRPA--EDKIFPVPEEPPVKKLMRTSTPPPASVINNMLAEIFCQTGGVEDQEEWHAQVVEELSNFKSQKVLGLNEDPLKWWSDRLALFPLLPKVLQKYWCVTATRVAPERLFGSAANVVSAKRNRL 636          

Query:  601 SSIWNYFTVSP------LINSKAICNLCNVSLSRGGNESKSFTTSNLVQHLRSKHVVAFADFXXXXXXXXXXXXXXXTASIPRPATIEALLDR---RQPFEFNDKRALDWNKTIAEFMALDVQPFSVVDNVGFRRIIAKAEPRYTIPSSRYFSSTLIPAMHEKIQNKVREMVSSQPSTSLTSDAWSDPSISVALLSLTAHWVT----EDFQRKQAILAASPIEESHTGDYLGGMLLKILGDYTIEKSAVHVLLRDSGANMIKASRVADID-SISCFAHTLQLVINDSIMSQRSVKDILAISRSNVGKFRHSVLAQQHLSDLQGSLGVPKKKLVQDVQTRWNATLAMLRSLVEQKQVLGAYATE----HKLTNLDAHQWTLISHIIDTLSPFKDATKEVSDSQ-TSISVFLP------------KHTMSEGIMTMRQDILTSLNKRFAHTKE-NRKMVLATILDPRFKNFAYDDRELASTAKQWLKNECLILASAERSEEVVEPPSKRPRVETDQAHPGSSTSRLWDLFSDVVSEPALQTNSSI------IGNVND------AVDAMIALYLSSAALPRTENPYVWWNSNKLLFPYLATLSRRYLSAPASSVPSEQLFSGAWQIFSDRRGSL 2361
            S +W YF          L   K  C +C   ++  GN      TSNL  HL   H   F +F K + E+       + + +   ++ +   D    +    ++ K+  +    +   +   + P S+VD   F+ ++  A+PRY +PS +Y S+  IP  +  ++  + + ++      +++D W   + + A ++L AH++              L    + E +T + +  +L ++  ++ I  + V     + G +++KA  + D+   + C  HT    I  +    + +  +L+  R  V  F+ S +A   L + Q    V    LV +  + W +TLAML+ L EQ+ V+     E    H L  L+A +W  I  +++ L PFK   + +S S+  +IS+  P            K T S+ +   ++ I   L+K +  T E +  + +AT LDPR+K   +    L++  +Q ++N   ++  A+   + V+    RP    D+  P      +  L       PA   N+ +       G V D       V   ++ + S   L   E+P  WW+    LFP L  + ++Y    A+ V  E+LF  A  + S +R  L
Sbjct:   23 SKVWKYFGFDTNAEGCILQWKKIYCRICMAQIAYSGN------TSNLSYHLEKNHPEEFCEFVKSNTEQMREAFATAFSKLKPESSQQPGQDALAVKAGHGYDSKKQQELTAAVLGLICEGLYPASIVDEPTFKVLLKTADPRYELPSRKYISTKAIPEKYGAVREVILKELAEATWCGISTDMWRSENQNRAYVTLAAHFLGLGAPNCLSMGSRCLKTFEVPEENTAETITRVLYEVFIEWGI-SAKVFGATTNYGKDIVKACSLLDVAVHMPCLGHTFNAGIQQAFQLPK-LGALLSRCRKLVEYFQQSAVAMYMLYEKQKQQNVAHCMLVSNRVSWWGSTLAMLQRLKEQQFVIAGVLVEDSNNHHLM-LEASEWATIEGLVELLQPFKQVAEMLSASRYPTISMVKPLLHMLLNTTLNIKETDSKELSMAKEVIAKELSKTYQETPEIDMFLNVATFLDPRYKRLPF----LSAFERQQVENR--VVEEAKGLLDKVKDGGYRPA--EDKIFPVPEEPPVKKLMRTSTPPPASVINNMLAEIFCQTGGVEDQEEWHAQVVEELSNFKSQKVLGLNEDPLKWWSDRLALFPLLPKVLQKYWCVTATRVAPERLFGSAANVVSAKRNRL 636          

Query:  601 SSIWNYFTVSP------LINSKAICNLCNVSLSRGGNESKSFTTSNLVQHLRSKHVVAFADFXXXXXXXXXXXXXXXTASIPRPATIEALLDR---RQPFEFNDKRALDWNKTIAEFMALDVQPFSVVDNVGFRRIIAKAEPRYTIPSSRYFSSTLIPAMHEKIQNKVREMVSSQPSTSLTSDAWSDPSISVALLSLTAHWVT----EDFQRKQAILAASPIEESHTGDYLGGMLLKILGDYTIEKSAVHVLLRDSGANMIKASRVADID-SISCFAHTLQLVINDSIMSQRSVKDILAISRSNVGKFRHSVLAQQHLSDLQGSLGVPKKKLVQDVQTRWNATLAMLRSLVEQKQVLGAYATE----HKLTNLDAHQWTLISHIIDTLSPFKDATKEVSDSQ-TSISVFLP------------KHTMSEGIMTMRQDILTSLNKRFAHTKE-NRKMVLATILDPRFKNFAYDDRELASTAKQWLKNECLILASAERSEEVVEPPSKRPRVETDQAHPGSSTSRLWDLFSDVVSEPALQTNSSI------IGNVND------AVDAMIALYLSSAALPRTENPYVWWNSNKLLFPYLATLSRRYLSAPASSVPSEQLFSGAWQIFSDRRGSL 2361
            S +W YF          L   K  C +C   ++  GN      TSNL  HL   H   F +F K + E+       + + +   ++ +   D    +    ++ K+  +    +   +   + P S+VD   F+ ++  A+PRY +PS +Y S+  IP  +  ++  + + ++      +++D W   + + A ++L AH++              L    + E +T + +  +L ++  ++ I  + V     + G +++KA  + D+   + C  HT    I  +    + +  +L+  R  V  F+ S +A   L + Q    V    LV +  + W +TLAML+ L EQ+ V+     E    H L  L+A +W  I  +++ L PFK   + +S S+  +IS+  P            K T S+ +   ++ I   L+K +  T E +  + +AT LDPR+K   +    L++  +Q ++N   ++  A+   + V+    RP    D+  P      +  L       PA   N+ +       G V D       V   ++ + S   L   E+P  WW+    LFP L  + ++Y    A+ V  E+LF  A  + S +R  L
Sbjct:   23 SKVWKYFGFDTNAEGCILQWKKIYCRICMAQIAYSGN------TSNLSYHLEKNHPEEFCEFVKSNTEQMREAFATAFSKLKPESSQQPGQDALAVKAGHGYDSKKQQELTAAVLGLICEGLYPASIVDEPTFKVLLKTADPRYELPSRKYISTKAIPEKYGAVREVILKELAEATWCGISTDMWRSENQNRAYVTLAAHFLGLGAPNCLSMGSRCLKTFEVPEENTAETITRVLYEVFIEWGI-SAKVFGATTNYGKDIVKACSLLDVAVHMPCLGHTFNAGIQQAFQLPK-LGALLSRCRKLVEYFQQSAVAMYMLYEKQKQQNVAHCMLVSNRVSWWGSTLAMLQRLKEQQFVIAGVLVEDSNNHHLM-LEASEWATIEGLVELLQPFKQVAEMLSASRYPTISMVKPLLHMLLNTTLNIKETDSKELSMAKEVIAKELSKTYQETPEIDMFLNVATFLDPRYKRLPF----LSAFERQQVENR--VVEEAKGLLDKVKDGGYRPA--EDKIFPVPEEPPVKKLMRTSTPPPASVINNMLAEIFCQTGGVEDQEEWHAQVVEELSNFKSQKVLGLNEDPLKWWSDRLALFPLLPKVLQKYWCVTATRVAPERLFGSAANVVSAKRNRL 636          

Query:  886 KRALDWNKTIAEFMALDVQPFSVVDNVGFRRIIAKAEPRYTIPSSRYFSSTLIPAMHEKIQNKVREMVSSQPSTSLTSDAWSDPSISVALLSLTAHWVTEDFQRKQAILAASPIEESHTGDYLGGMLLKILGDYTIEKSAVHVLLRDSGANMIKASRVADIDSISCFAHTLQLVINDSIMSQRSVKDILAISRSNVGKFRHSVLAQQHLSDLQGSLGVPKKKLVQDVQTRWNATLAML-RSLVEQKQVLGAYATEHKLTNLDAHQWTLISHIIDTLSPFKDATKEVSDSQTSISVFLP---------KHTMS--EGIMTMRQDILTSLNKRFAHTKENRKMVLATILDPRFKN-FAYDDRELASTAKQWLKNECLILASAERSEEVVEPPSKRPRVETDQAHPGSSTSRLWDLFSDVVSEPALQTNSSIIGNVNDAVDAMIAL--YLSSAALPRTENPYVWWNS--NKLLFPYLATLSRRYLSAPASSVPSEQLFSGAWQIFSDRRGSLTAGKGEMLLLLKYNLP 2409
            K +   ++ I   +A+D+   + V+  GF+ +IA   P + + S    +   +P ++++ + K+ + + S     L  D WSD      +  +  +++  +    + +   +  E  HT   +   L +++ +Y IE   V  + RD G+N+  A  +   +S  C +H L L  ND+  +   V  +L + +  V K + S +  +    +Q  L +P   L +    RW+    M  R+L+ +  +     T + L  L  + W +I ++ D  +P    +K+  D +T  S  +P         K ++   E    +   +   L K  A     R +  AT+LDPR+K+ F  D+ +     +    NE  +  +++    +++  S      +D+A P  +    ++ F     E  +      I N ++++ A + +  YLS++      NP  +W S     ++P L   + R++  P+ S   E++FS A  I +  R SL +   ++ L L  N+P
Sbjct:  104 KESAKIHRAITSMIAIDLMSLTTVEKPGFKNLIATLRPNFKLKSRWSITREDLPNLYDEYKAKLEDELLSVDHAVLGFDLWSDEGSKHEVNGVIVYFLQNNEVVHRVLGVLNCRESKHTAQNIALGLKELISEYKIEGKIV-CMCRDGGSNVQNACDLLKCESFDCLSHKLHLAANDATKNMVGVGRVLLLYKKLVRKLKKSTVTAKQFESIQEVLELPVLCLQKSSSVRWSHMKLMFDRALIRKSAIEKLMETNNTLPQLTENDWNVIQNVSDVFTPIDLFSKKTQDRETPASQVIPLCYALIDHCKESIDHPEAFKAIEDRMQKELKKYSA----CRYLQFATLLDPRYKDHFCTDEFKHMFIEEFEKCNEDDVYITSDNEVRLLDSHSD----SSDEA-PAKNAKFDFEKF----IEKRISEQPKPIPNCDNSLTARMEVQRYLSTSV--EQVNPRQFWTSRVTTSVYPRLCKFAARFIICPSGSAEVERVFSTAGVILNKFRKSLYSEHFKLHLFLSKNIP 612          

Query:  595 LTSSIWNYFTVSPLINSKAICNLCNVSLSRGGNESKSFTTSNLVQHLRSKH----VVAFADFXXXXXXXXXXXXXXXTASIPRPATIEALLDRRQPFEFNDKRALDWNKTIAEFMALDVQPFSVVDNVGFRRIIAKAEPRYTIPSSRYFSSTLIPAMHEKIQNKVREMVSSQPSTSLTSDAWSDPSISVALLSLTAHWVTEDFQRKQAILAASPIEESHTGDYLGGMLLKILGDYTIEKSAVHVLLRDSGANMIKASRVADIDSISCFAHTLQLVINDSIMSQRSVKDILAISRSNVGKFRHSVLAQQHLSDLQGSLGVPKKKLVQDVQTRWNATLAMLRSLVEQKQVLGAYATEHKLTNLDAHQWTLISHIIDTLSPFKDATKEVSDSQTSISVFLP-----------KHTMSEGIMTMRQDILTSLNKRFAHTKENRKMVLATILDPRFKNFAYDDRELASTAKQWLKNECLILASAERSEEVVEPPSKRPRVETDQAHPGSSTSRLWDLFSDVVSEPALQTNSSIIGNVNDAVDAMIALYLSSAALPRTENPYVWWNS-NKLLFPYLATLSRRYLSAPASSVPSEQLFSGAWQIFSDRRGSLTAGKGEMLLLLKYNL 2406
            + S +W+YF    L + +  CNLCN  L+RG   S    T NL+ HL   H    V+        ++E     + QS        T+++  +      +ND    +  K+I E + +D  P +  D  GF+R +    P Y + S     S  +P ++++ ++++R  ++      L+ D WSD      ++ +T +++  +   ++ I   +  ++ H G Y+   L  ++  + +    V V+ RD  + +  A     I S++CF   L L   ++      +  +L   +  V   ++S +  Q    +Q  + +P   L       W         ++E +QV+       +L  L +  W L+  +++ L+P    +K     ++S SV +P                E  + +++ +   L+K  +     + +  +T+LDPR+K+   +D + ++  K  ++ E   +    R+ E          + ++   P   + +L D  + +  +   +   + +      V   +  YLS+A    T   + W N   K  +P LA  +RR++  P  S  +E+LFS       + R +L+    +ML+ L  N+
Sbjct:    2 VKSRVWDYFL--KLQDGRNKCNLCNKILARGSRGS----THNLISHLTRVHPKEYVLQEEPPVMIAQEDSSEFSFQSNNMKTEDFTMQSFFEPEFMKLYNDN---NITKSIMEMICMDSMPMTTTDRAGFKRFMTSVCPDYELKSPSSMISYELPKLYQEYEDQLRMELNLAEHVVLSVDIWSDKGSIQEMIGVTGNFLKNEKVVRRTIGVINYQKDVHNGVYVAAELDNLMARFNL-NGKVEVVCRDYNSIVENACDHLKISSVNCFNQQLHLAACEAKSKIGQINRVLLNCKLLVKNLKNSSVTWQTSEKIQSLMEIPNLCLNHCSDECWCFLQEFFGRVIECQQVI------EELQKLQSSDWDLMRDVVEILAPLSKFSKLSESKESSASVIIPYCDYLVKAYESTQNQPEAFLAVKEHMERELHKYTSC----QYLKFSTLLDPRYKDLYTNDSDTSNLIKA-IETEFETMDYKNRTFE---------EISSELCGPAPKSQKL-DFDAYIQEKIKSRGKHNALTGEKLTVRMEVTRYLSTAVEDVTPRDF-WLNDVTKASYPRLAKFARRFIICPTGSSAAEKLFSTDRATMDEYRNTLSDENLKMLIFLNKNI 589          

Query:  443 WLTLEICREYMRGECLRDEFSCRYAHPAKNLETQSGRVICCYDYLK 580
            WL +E+CRE++RG+C R +  C++AHP  N++ Q GRV  CYD +K
Sbjct:   38 WLQVEVCREFLRGQCARSDQECKFAHPPPNVDVQQGRVTACYDSIK 83          

Query:  443 WLTLEICREYMRGECLRDEFSCRYAHPAKNLETQSGRVICCYDYLK 580
            WL +E+CRE++RG+C R +  C++AHP  N++ Q GRV  CYD +K
Sbjct:   38 WLQVEVCREFLRGQCARSDQECKFAHPPPNVDVQQGRVTACYDSIK 83          

Query:  443 WLTLEICREYMRGECLRDEFSCRYAHPAKNLETQSGRVICCYDYLK 580
            WL +E+CRE++RG+C R +  C++AHP  N++ Q GRV  CYD +K
Sbjct:   38 WLQVEVCREFLRGQCARSDQECKFAHPPPNVDVQQGRVTACYDSIK 83          

Query:  583 MSKQLTSSIWNYFTVSPLINSKAICNLCNVSLSRGGNESKSFTTSNLVQHLRSKHVVAFADFXXXXXXXXXXXXXXXTASIPRP-ATIEALLDR--RQPFEFNDKRALDWNKTIAEFMALDV--QPFSVVDNVGFRRIIAKAEPRYTIPSSRYFSSTLIPAMHEKIQNKVREMVSSQPSTSLTSDAWSDPSISVALLSLTAHWVTEDFQRKQAILAASPIEESHTGDYLGGMLLKILGDYTIE--KSAVHVLLRDSGANMIKASRVADIDSISCFAHTLQLVINDSIMSQRSVKDILAISRSNVGKFRHSVLAQQHLSDLQGSLGVPKKKLVQDVQT-------RWNATLAMLRSLVEQKQVLGAYATEHKLTNLDAHQWTLISHIIDTLSPFKDATKEVSDSQTSISVFLP--------------KHTMSEGIMTMRQDILTSLNKRFAHTKENRKMVLATILDPRFKNFAYDDRELASTAKQWLKNECLILASAERSEEVVEPPSKRPRVETDQAHPGSS-TSRLWDLFSDVVSEPALQTNSSIIGNVNDAVDAMIALYLSSAALPRTENPYVWWNSNKLLFPYLATLSRRYLSAPASSVPSEQLFSGAWQIFSDRRGSLTAGKGEMLLLLKYNLPQFSFN 2424
            MSK+  S++W YF  +    + A C LCN + SR G       T+ L  HL+SKH   F     + K     +++ S  S   P A +E  L      P +  D   + ++K   E +AL +    F  ++  GF   I   +PRYTI    Y+   L   +  K+   +++ V    + SL++  W        LLSL+   ++ DFQ  + +L    +    T   L   +  ++    IE  K  +H ++RD    +     + D     C  H LQ+ +  ++ S   ++++ +  +  V  F  S +A  HL  +Q      + +L +D  T       +WN+   M+ S+   K  L  Y  E+ L  +   +W  I      + P ++  K  S+  T+ S  +P                  S  I +  + +L  L  +FAH   +   ++AT LDPR+K   + +RE     +Q + NE L+  +    +   +PP K  +V +  +    S    + D      +    Q N+S+       +  ++ LY S   + R  +P +WW SN + +  L  + R++LSAPA+SV SE LF  +  ++ D +  L+      +LL+K N   FSF+
Sbjct:    1 MSKK-KSNVWQYFYKTS--GTVATCLLCNRNYSRRGR-----GTTCLRNHLKSKHPPEFLSLSGDIKYLDLVKSEISIGSPQHPTAQLELNLHETDSDPLDTED---ISYSKRCDEKLALMLLNHSFEFIEGPGFVNFIRTLQPRYTIQPRSYYEKILCEDIQRKMHQHLKQQVDLLDAISLSTSLWRGDK-GEGLLSLSCSGISRDFQTHRLMLKCEALNYESTSK-LACCIRDLVPSLAIEVPKEKIHCVIRDEMTAL--PGSLPD-----CSVHRLQMCVRFALQSNELLQNLSSKCKQIVDHFASSKMANDHLKFIQ------EIRLTRDPCTLTPYDPCQWNSAFQMMSSVFRMKDALSLYCEEYSLVQIYPDEWIEIDLCSKVMQPCEETIKIWSNPSTTTSSVIPLVAALRDSLRTDVHNFVSSVTICSFARKLLEELEMKFAHITSDINFLMATYLDPRYKQAFFTERE-----EQLVANEVLLQLAGVPEDCNGQPPLKIIKVSSTSSQKNESKIDSILDSILTTGTTNTQQPNTSM--GSQSQIKNLLYLYNSEPRIDRNMDPLIWWRSN-IKYISLYGIVRKFLSAPAASVVSEGLFRKSTHLYFDMQAGLSPESASKMLLMKAN---FSFS 606          

Query:  583 MSKQLTSSIWNYFTVSPLINSKAICNLCNVSLSRGGNESKSFTTSNLVQHLRSKHVVAFADFXXXXXXXXXXXXXXXTASIPRP-ATIEALLDR--RQPFEFNDKRALDWNKTIAEFMALDV--QPFSVVDNVGFRRIIAKAEPRYTIPSSRYFSSTLIPAMHEKIQNKVREMVSSQPSTSLTSDAWSDPSISVALLSLTAHWVTEDFQRKQAILAASPIEESHTGDYLGGMLLKILGDYTIE--KSAVHVLLRDSGANMIKASRVADIDSISCFAHTLQLVINDSIMSQRSVKDILAISRSNVGKFRHSVLAQQHLSDLQGSLGVPKKKLVQDVQT-------RWNATLAMLRSLVEQKQVLGAYATEHKLTNLDAHQWTLISHIIDTLSPFKDATKEVSDSQTSISVFLP--------------KHTMSEGIMTMRQDILTSLNKRFAHTKENRKMVLATILDPRFKNFAYDDRELASTAKQWLKNECLILASAERSEEVVEPPSKRPRVETDQAHPGSS-TSRLWDLFSDVVSEPALQTNSSIIGNVNDAVDAMIALYLSSAALPRTENPYVWWNSNKLLFPYLATLSRRYLSAPASSVPSEQLFSGAWQIFSDRRGSLTAGKGEMLLLLKYNLPQFSFN 2424
            MSK+  S++W YF  +    + A C LCN + SR G       T+ L  HL+SKH   F     + K     +++ S  S   P A +E  L      P +  D   + ++K   E +AL +    F  ++  GF   I   +PRYTI    Y+   L   +  K+   +++ V    + SL++  W        LLSL+   ++ DFQ  + +L    +    T   L   +  ++    IE  K  +H ++RD    +     + D     C  H LQ+ +  ++ S   ++++ +  +  V  F  S +A  HL  +Q      + +L +D  T       +WN+   M+ S+   K  L  Y  E+ L  +   +W  I      + P ++  K  S+  T+ S  +P                  S  I +  + +L  L  +FAH   +   ++AT LDPR+K   + +RE     +Q + NE L+  +    +   +PP K  +V +  +    S    + D      +    Q N+S+       +  ++ LY S   + R  +P +WW SN + +  L  + R++LSAPA+SV SE LF  +  ++ D +  L+      +LL+K N   FSF+
Sbjct:    1 MSKK-KSNVWQYFYKTS--GTVATCLLCNRNYSRRGR-----GTTCLRNHLKSKHPPEFLSLSGDIKYLDLVKSEISIGSPQHPTAQLELNLHETDSDPLDTED---ISYSKRCDEKLALMLLNHSFEFIEGPGFVNFIRTLQPRYTIQPRSYYEKILCEDIQRKMHQHLKQQVDLLDAISLSTSLWRGDK-GEGLLSLSCSGISRDFQTHRLMLKCEALNYESTSK-LACCIRDLVPSLAIEVPKEKIHCVIRDEMTAL--PGSLPD-----CSVHRLQMCVRFALQSNELLQNLSSKCKQIVDHFASSKMANDHLKFIQ------EIRLTRDPCTLTPYDPCQWNSAFQMMSSVFRMKDALSLYCEEYSLVQIYPDEWIEIDLCSKVMQPCEETIKIWSNPSTTTSSVIPLVAALRDSLRTDVHNFVSSVTICSFARKLLEELEMKFAHITSDINFLMATYLDPRYKQAFFTERE-----EQLVANEVLLQLAGVPEDCNGQPPLKIIKVSSTSSQKNESKIDSILDSILTTGTTNTQQPNTSM--GSQSQIKNLLYLYNSEPRIDRNMDPLIWWRSN-IKYISLYGIVRKFLSAPAASVVSEGLFRKSTHLYFDMQAGLSPESASKMLLMKAN---FSFS 606          

Query:  946 FSVVDNVGFRRIIAKAEPRYTIPSSRYFSSTLIPAMHEKIQNKVREMVSSQPSTSLTSDAWSDPSISVALLSLTAHWVTEDFQRKQAILAASPIEESHTGDYLGGMLLKILGDYTIE--KSAVHVLLRDSGANMIKASRVADIDSISCFAHTLQLVINDSIMSQRSVKDILAISRSNVGKFRHSVLAQQHLSDLQGSLGVPKKKLVQDVQT-------RWNATLAMLRSLVEQKQVLGAYATEHKLTNLDAHQWTLISHIIDTLSPFKDATKEVSDSQTSISVFLP--------------KHTMSEGIMTMRQDILTSLNKRFAHTKENRKMVLATILDPRFKNFAYDDRELASTAKQWLKNECLILASAERSEEVVEPPSKRPRVETDQAHPGSS-TSRLWDLFSDVVSEPALQTNSSIIGNVNDAVDAMIALYLSSAALPRTENPYVWWNSNKLLFPYLATLSRRYLSAPASSVPSEQLFSGAWQIFSDRRGSLTAGKGEMLLLLKYNLPQFSFN 2424
            F  ++  GF   I   +PRYTI    Y+   L   +  K+   +++ V    + SL++  W        LLSL+   ++ DFQ  + +L    +    T   L   +  ++    IE  K  +H ++RD    +     + D     C  H LQ+ +  ++ S   ++++ +  +  V  F  S +A  HL  +Q      + +L +D  T       +WN+   M+ S+   K  L  Y  E+ L  +   +W  I      + P ++  K  S+  T+ S  +P                  S  I +  + +L  L  +FAH   +   ++AT LDPR+K   + +RE     +Q + NE L+  +    +   +PP K  +V +  +    S    + D      +    Q N+S+       +  ++ LY S   + R  +P +WW SN + +  L  + R++LSAPA+SV SE LF  +  ++ D +  L+      +LL+K N   FSF+
Sbjct:    7 FEFIEGPGFVNFIRTLQPRYTIQPRSYYEKILCEDIQRKMHQHLKQQVDLLDAISLSTSLWRGDK-GEGLLSLSCSGISRDFQTHRLMLKCEALNYESTSK-LACCIRDLVPSLAIEVPKEKIHCVIRDEMTAL--PGSLPD-----CSVHRLQMCVRFALQSNELLQNLSSKCKQIVDHFASSKMANDHLKFIQ------EIRLTRDPCTLTPYDPCQWNSAFQMMSSVFRMKDALSLYCEEYSLVQIYPDEWIEIDLCSKVMQPCEETIKIWSNPSTTTSSVIPLVAALRDSLRTDVHNFVSSVTICSFARKLLEELEMKFAHITSDINFLMATYLDPRYKQAFFTERE-----EQLVANEVLLQLAGVPEDCNGQPPLKIIKVSSTSSQKNESKIDSILDSILTTGTTNTQQPNTSM--GSQSQIKNLLYLYNSEPRIDRNMDPLIWWRSN-IKYISLYGIVRKFLSAPAASVVSEGLFRKSTHLYFDMQAGLSPESASKMLLMKAN---FSFS 497          

Query:  443 WLTLEICREYMRGECLRDEFSCRYAHPAKNLETQSGRVICCYDYLK 580
            WL LE+CRE+ R +C R +  C++AHP  N+E Q+G+V  CYD +K
Sbjct:   18 WLQLEVCREFQRNKCSRQDTECKFAHPPANVEVQNGKVTACYDSIK 63          

Query:  443 WLTLEICREYMRGECLRDEFSCRYAHPAKNLETQSGRVICCYDYLK 580
            WL LE+CRE+ R +C R +  C++AHP  N+E Q+G+V  CYD +K
Sbjct:   18 WLQLEVCREFQRNKCSRQDTECKFAHPPANVEVQNGKVTACYDSIK 63          

Query:  598 TSSIWNYFTVSPLINSKAICNLCNVSLSRGGNESKSFTTSNLVQHLRSKHVVAFADFXXXXXXXXXXXXXXXTASIPRPATIEALLDRRQPFEFNDKRALDWNKTIAEFMALDVQPFSVVDNVGFRRIIAKAEPRYTIPSSRYFSSTLIPAMHEKIQNKVREMVSSQPS--TSLTSDAWSDPSISVALLSLTAHWVT---------EDFQRKQAILAASPIEESHTGDYLGGML-----LKILGDYTIEKSAVHVLLRDSGANMIK-ASRVADIDSISCFAHTLQLVINDSIMSQRSVKDILAISRSNVGKFRHSVLAQQHLSDLQGSLGVPKKKLVQDVQTRWNATLAMLRSLVEQKQVLGAYATEHKLTNL-DAHQWTLISHIIDTLSPFKDATKEVSDSQTSISVFLP-------------KHTMSEGIMTMRQDILTSLNKRFAHTKENRKMVLATILDPRFKNFAYDDRELASTAKQWLKNECLILASAERSEEVVEPPSKRPRVETDQAHPGSSTS------RLWDLFSDVVSEPALQTNSSIIGNVNDAVDAMIALYLSSAALPRTENPYVWWNSNKLLFPYLATLSRRYLSAPASSVPSEQLFSGAWQIFSDRRGSLTAGKGEMLLLLKYNLPQFSF 2421
            TS +WN+F++S    +K +C  C+ ++SRG  ++ +  TS L +H++  H        + +           T        I    +  + F      A    K IAE +ALD+QP +VV+NVG  R++   +P+Y++P S YF+ST IP M+E ++  V   +          T+  W   S +   L LTAHWV+         +DF    A+L  + I+     DY   ML     L+ L D  +  S + +    +    I+      D  ++ CF H + L++N++I SQR V+++L+I+R    +   S  A++ L++LQ    +P+ +LVQDV ++W  +  ML  LVEQK+ +   + E     L    QW ++  + + L PF  A +E+S+   ++   +P               TM  GI  M + +  +L  R + T  + + + AT+LDPR+K   + + E A   K  L  E L ++++  +E      +K P        P SS S       LW L  D+  +   +           +++  +  YL    L ++ +P  +WN  KLL+P LA ++ RY+  P S VP++ LFS +    +  +        E LL LK NLP   F
Sbjct:  633 TSKLWNHFSISSADPTKVVCLHCSRTISRG-KKTTNLGTSCLFRHMQRFH----GHVLENNSNISGDGPSAETQVKQELMDISTYQENAEKFSECHPAAKKITKLIAEMLALDLQPSTVVENVGLNRLLEYLQPQYSLPPSSYFTSTAIPEMYESVKEVVLTHLKEAEGGIIHFTTSVWIG-SQTQEYLILTAHWVSFESQVLPQGQDFH-CSALLGVASID----CDY--NMLNIQKQLEYLWDTWMGSSGLKIGFTVTDNQTIRNVLESCDHTTMQCFVHNIDLIVNEAIKSQRMVQNLLSIARKICERVHRSAKAKEKLAELQKVYQLPENQLVQDVPSKWKTSYFMLERLVEQKKAIDEMSIECNFRELISCDQWEVMGSVCNALKPFVVACREMSNRTATLGQVIPLIHILNRKIDMLFDETM--GIDNMLKSLKEALVTRMSPTLHDPRYIWATMLDPRYKTSLFTEEE-AEQCKHDLIQE-LEVSTSNSAE------TKTPLSNGCSEIPASSNSLASNKENLWSLMDDIRQKIKQEEKPK-------SLELAVLEYLEEDILDQSCDPLDYWNLKKLLWPDLAKVAVRYVGCPPSIVPADTLFSTSTVNCALNQSRPLLENFEGLLFLKVNLPLIYF 1247          

Query:  598 TSSIWNYFTVSPLINSKAICNLCNVSLSRGGNESKSFTTSNLVQHLRSKHVVAFADFXXXXXXXXXXXXXXXTASIPRPATIEALLDRRQPFEFNDKRALDWNKTIAEFMALDVQPFSVVDNVGFRRIIAKAEPRYTIPSSRYFSSTLIPAMHEKIQNKVREMVSSQPS--TSLTSDAWSDPSISVALLSLTAHWVT---------EDFQRKQAILAASPIEESHTGDYLGGML-----LKILGDYTIEKSAVHVLLRDSGANMIK-ASRVADIDSISCFAHTLQLVINDSIMSQRSVKDILAISRSNVGKFRHSVLAQQHLSDLQGSLGVPKKKLVQDVQTRWNATLAMLRSLVEQKQVLGAYATEHKLTNL-DAHQWTLISHIIDTLSPFKDATKEVSDSQTSISVFLP-------------KHTMSEGIMTMRQDILTSLNKRFAHTKENRKMVLATILDPRFKNFAYDDRELASTAKQWLKNECLILASAERSEEVVEPPSKRPRVETDQAHPGSSTS------RLWDLFSDVVSEPALQTNSSIIGNVNDAVDAMIALYLSSAALPRTENPYVWWNSNKLLFPYLATLSRRYLSAPASSVPSEQLFSGAWQIFSDRRGSLTAGKGEMLLLLKYNLPQFSF 2421
            TS +WN+F++S    +K +C  C+ ++SRG  ++ +  TS L +H++  H        + +           T        I    +  + F      A    K IAE +ALD+QP +VV+NVG  R++   +P+Y++P S YF+ST IP M+E ++  V   +          T+  W   S +   L LTAHWV+         +DF    A+L  + I+     DY   ML     L+ L D  +  S + +    +    I+      D  ++ CF H + L++N++I SQR V+++L+I+R    +   S  A++ L++LQ    +P+ +LVQDV ++W  +  ML  LVEQK+ +   + E     L    QW ++  + + L PF  A +E+S+   ++   +P               TM  GI  M + +  +L  R + T  + + + AT+LDPR+K   + + E A   K  L  E L ++++  +E      +K P        P SS S       LW L  D+  +   +           +++  +  YL    L ++ +P  +WN  KLL+P LA ++ RY+  P S VP++ LFS +    +  +        E LL LK NLP   F
Sbjct:  633 TSKLWNHFSISSADPTKVVCLHCSRTISRG-KKTTNLGTSCLFRHMQRFH----GHVLENNSNISGDGPSAETQVKQELMDISTYQENAEKFSECHPAAKKITKLIAEMLALDLQPSTVVENVGLNRLLEYLQPQYSLPPSSYFTSTAIPEMYESVKEVVLTHLKEAEGGIIHFTTSVWIG-SQTQEYLILTAHWVSFESQVLPQGQDFH-CSALLGVASID----CDY--NMLNIQKQLEYLWDTWMGSSGLKIGFTVTDNQTIRNVLESCDHTTMQCFVHNIDLIVNEAIKSQRMVQNLLSIARKICERVHRSAKAKEKLAELQKVYQLPENQLVQDVPSKWKTSYFMLERLVEQKKAIDEMSIECNFRELISCDQWEVMGSVCNALKPFVVACREMSNRTATLGQVIPLIHILNRKIDMLFDETM--GIDNMLKSLKEALVTRMSPTLHDPRYIWATMLDPRYKTSLFTEEE-AEQCKHDLIQE-LEVSTSNSAE------TKTPLSNGCSEIPASSNSLASNKENLWSLMDDIRQKIKQEEKPK-------SLELAVLEYLEEDILDQSCDPLDYWNLKKLLWPDLAKVAVRYVGCPPSIVPADTLFSTSTVNCALNQSRPLLENFEGLLFLKVNLPLIYF 1247          

Query:  598 TSSIWNYFTVSPLINSKAICNLCNVSLSRGGNESKSFTTSNLVQHLRSKHVVAFADFXXXXXXXXXXXXXXXTASIPRPATIEALLDRRQPFEFNDKRALDWNKTIAEFMALDVQPFSVVDNVGFRRIIAKAEPRYTIPSSRYFSSTLIPAMHEKIQNKVREMVSSQPS--TSLTSDAWSDPSISVALLSLTAHWVT---------EDFQRKQAILAASPIEESHTGDYLGGML-----LKILGDYTIEKSAVHVLLRDSGANMIK-ASRVADIDSISCFAHTLQLVINDSIMSQRSVKDILAISRSNVGKFRHSVLAQQHLSDLQGSLGVPKKKLVQDVQTRWNATLAMLRSLVEQKQVLGAYATEHKLTNL-DAHQWTLISHIIDTLSPFKDATKEVSDSQTSISVFLP-------------KHTMSEGIMTMRQDILTSLNKRFAHTKENRKMVLATILDPRFKNFAYDDRELASTAKQWLKNECLILASAERSEEVVEPPSKRPRVETDQAHPGSSTS------RLWDLFSDVVSEPALQTNSSIIGNVNDAVDAMIALYLSSAALPRTENPYVWWNSNKLLFPYLATLSRRYLSAPASSVPSEQLFSGAWQIFSDRRGSLTAGKGEMLLLLKYNLPQFSF 2421
            TS +WN+F++S    +K +C  C+ ++SRG  ++ +  TS L +H++  H        + +           T        I    +  + F      A    K IAE +ALD+QP +VV+NVG  R++   +P+Y++P S YF+ST IP M+E ++  V   +          T+  W   S +   L LTAHWV+         +DF    A+L  + I+     DY   ML     L+ L D  +  S + +    +    I+      D  ++ CF H + L++N++I SQR V+++L+I+R    +   S  A++ L++LQ    +P+ +LVQDV ++W  +  ML  LVEQK+ +   + E     L    QW ++  + + L PF  A +E+S+   ++   +P               TM  GI  M + +  +L  R + T  + + + AT+LDPR+K   + + E A   K  L  E L ++++  +E      +K P        P SS S       LW L  D+  +   +           +++  +  YL    L ++ +P  +WN  KLL+P LA ++ RY+  P S VP++ LFS +    +  +        E LL LK NLP   F
Sbjct:  633 TSKLWNHFSISSADPTKVVCLHCSRTISRG-KKTTNLGTSCLFRHMQRFH----GHVLENNSNISGDGPSAETQVKQELMDISTYQENAEKFSECHPAAKKITKLIAEMLALDLQPSTVVENVGLNRLLEYLQPQYSLPPSSYFTSTAIPEMYESVKEVVLTHLKEAEGGIIHFTTSVWIG-SQTQEYLILTAHWVSFESQVLPQGQDFH-CSALLGVASID----CDY--NMLNIQKQLEYLWDTWMGSSGLKIGFTVTDNQTIRNVLESCDHTTMQCFVHNIDLIVNEAIKSQRMVQNLLSIARKICERVHRSAKAKEKLAELQKVYQLPENQLVQDVPSKWKTSYFMLERLVEQKKAIDEMSIECNFRELISCDQWEVMGSVCNALKPFVVACREMSNRTATLGQVIPLIHILNRKIDMLFDETM--GIDNMLKSLKEALVTRMSPTLHDPRYIWATMLDPRYKTSLFTEEE-AEQCKHDLIQE-LEVSTSNSAE------TKTPLSNGCSEIPASSNSLASNKENLWSLMDDIRQKIKQEEKPK-------SLELAVLEYLEEDILDQSCDPLDYWNLKKLLWPDLAKVAVRYVGCPPSIVPADTLFSTSTVNCALNQSRPLLENFEGLLFLKVNLPLIYF 1247          

Query:  583 MSKQLTSSIWNYFTVSPLINSKAICNLCNVSLSRGGNESKSFTTSNLVQHLRSKHVVAFADFXXXXXXXXXXXXXXXTASIPR--PATIEALLDRRQPFEFNDKRALDWNKTIAEFMALDVQPFSVVDNVGFRRIIAKAEPRYTIPSSRYFSSTLIPAMHEKIQNKVREMVSSQPSTSLTSDAWSDPSI----SVALLSLTAHWVTEDFQRKQAILAASP----------------IEESHTGDYLGGMLLKILGDYTIEKSAVHVLL---------------------RDSGANMIKAS-----------RVADIDSISCFAHTLQLVINDSIMSQRSVKDILAISRSN-VGKFRHSVLAQQHLSDLQGSLGVPKKKLVQDVQTRWNATLAMLRSLVEQKQVLGAYATEHKLTNLDAHQWTLISHIIDTLSPFKDATKEV-SDSQTSISVFLP-------------KHTMSEGIMTMRQDILTSLNKRFAHTKENRKMVLATILDPRFKNFAYDDRELASTAKQWLKNECLILASAERSEEVVEPPSKRPRVETDQAHPGSSTSRLWDLFSDVVSEPALQTNSSIIGNVNDAVDAMIALYLSSAALPRTENPYVWWNSNKLLFPYLATLSRRYLSAPASSVPSEQLFSGAWQIFSDRRGSLTAGKGEMLLLLKYN 2403
            M+ +   SI +YF +     +  I + C    +R   ++K   TSN V HL+ KH   + +F ++   K+EA    +     R  P T   L      F+++D R    ++ IA+ +  D+QP  +V+  GFR ++   EPRY      Y    L+PA   ++Q   ++ +    S S+T D W   S+        L +T H++  D+  + A+LA  P                I ESH    + G + +++ D    +S     L                      D G    K             +      I CFA  L   I + + +   V   L +++++ +  +  + +A + L  + GS    ++    D   +WN  L +LR +V+    L      + L  L   +  L+  +++ L PF++A+  V  D   SIS+ LP              H  S  +M + Q    +L++R A   E+   V AT LDP+FK  ++      S+   W K   ++L   E+    + P       +        S S+   LFS +   P +Q  +         V+  ++ YL     P  E+P  +W    + FP L+ ++++  + PA++   +Q+F+   +     +        + L+ LK N
Sbjct:    1 MASKSRVSILDYFNIVCEGENGKIESNCKACGTR--IQAKRTVTSNFVTHLKRKHQAMYDEFVRKKDVKREAMQTCTGPPSGRMIPQTAAGL----NKFDYSDPRQSLISEAIAKMIIRDLQPPQIVEYEGFRELLQLLEPRYIPVQCHYIQQQLLPAYVSQVQLAAKQALKGAESCSVTLDLWRSSSVGNSSGAGYLGVTCHFINADWHIRSALLACLPLPDHSNTQQMLSEFDEISESHG---ITGKVFRVVADLLPCESRSDFRLPGFSLIGNGEEDEEGEEDGSNGDPGEGESKEGISSNEYHRSLDQCLGRSRIDCFARLLAQCIKEGVCASPHVS--LPLNKASLLYNYIIATVAPEKLVQVFGSSANWQRPSSTD---KWNDQLKILRQMVDSMDFLEDIVDRNDLV-LGNLEKELLRELVEVLEPFEEASDMVQGDKHVSISLALPCVLGLRKHLAEVVTHQCSGIVMGLSQ----ALDRRLAGILEDPLYVTATTLDPQFK-LSW------SSDSDWHKQ--VLLEEVEKHTRTLSPIEHYSETQ-------PSPSKRCKLFSFIKQRPTMQAKT---------VEQELSTYLHEE--PTDEDPLQYWKRKSIDFPLLSQVAKKVFTVPATTTSVDQIFNTVSKTLRPDQCRFLPKNLDTLIYLKAN 630          

Query:  607 IWNYFTVSPLINSKAICNLCNVSLSRGGNESKSFTTSNLVQHLRSKHVVAFADFXXXXXXXXXXXXXXXTA-SIPRPATIEALLDRRQPFEFNDKRALDWNKTIAEFMALDVQPFSVVDNVGFRRIIAKAEPRYTIPSSRYFSSTLIPAMHEKIQNKVREMVSSQPSTSLTSDAWSDPSISVALLSLTA-HWVTEDFQRKQAILAASPIEESHTGDYLGGMLLKILGDYTIEKSAVHVLLRDSGANMIKA-----------------------SRVAD---------IDSISCFAHTLQLVINDSIMSQRSVKDILAISRSNVGKFRHSVLAQQHLSDLQGSLGVPKKKLVQDVQTRWNATLAMLRSLVEQKQVLGAYATEHKLTNLDAHQWTLISHIIDTLSPFKDATKEVSDSQTSISVFLP------KHTMSEGIMTMRQDILT-------SLNKRFA 1848
            IW+ FT     N K++C  C V ++ G N      T+NL +HL++ H       QK S +      K S A S  +   I   L R   ++   K      + IA ++     P + V++  F  ++   + R T+P     S+ LI   +E  + K RE +++    S+  D W+   ++ + L+++A ++  E  +    +LA   +   HT   +   + K + ++TI K  +  ++ D+G+NM+ A                       S + D         +D   C  HT+QLV++  +  + +VK +L  +RS V  FR S +A Q L D  G +      +V D  TRW++T  M+  L++ K  +   + +    +L   +W  +S + D L PF + TK +    TS+S+ +P       H     + T  +D+ T       +LN+RFA
Sbjct:   20 IWSNFTYDNKDN-KSVCKPCGVKIA-GKN------TTNLKRHLQTAHPEIHTKIQKMSDDHGPGGNKASDATSTTQQQAISDFL-RSSKYKTESKEQQTKEQAIARWIGRTGLPLTTVEDEDFVLMMGMIDGRLTVPKKTKISN-LIETQYEHERQKFRESLAAARKVSIGLDLWTKKGLTASFLAISACYFCVEKSKPAHILLALQQVGHPHTAQAIKACVDKCMQEWTIPKEKILTVITDNGSNMVAAFKNTTAEETSSEDDSPGSTIESDSEIDDQRYRHVDMELDRTPCVVHTIQLVVH-MLQKETTVKRVLDKARSVVKLFRKSSVATQKLLDQCGVI------VVNDCPTRWSSTFNMITRLLKVKDAVCQISNDMGWDSLLTSEWQKLSSLHDLLLPFAEHTKTLQSDTTSMSLVVPALFDLLTHLTDFAVNTRYRDLATLADKMRSNLNQRFA 463          

Query:  598 TSSIWNYFTVSPLINSKAICNLCNVSLSRGGNESKSFTTSNLVQHLRSKHVVAFADFXXXXXXXXXXXXXXXTASIPRPATIE----ALLDRRQPFEFNDKRALDWNKTIAEFMALDVQPFSVVDNVGFRRIIAKAEPRYTIPSSRYFSSTLIPAMHEKIQNKVREMVSSQPS--TSLTSDAWSDPSISVALLSLTAHWVT--------EDFQRKQAILAASPIEESHTGDYLGGMLLKILGDYTIEKSAVHVLLRDSGANMI-KASRVADIDSISCFAHTLQLVINDSIMSQRSVKDILAISRSNVGKFRHSVLAQQHLSDLQGSLGVPKKKLVQDVQTRWNATLAMLRSLVEQKQVLGAYATEHKLTNL-DAHQWTLISHIIDTLSPFKDATKEVSDSQTSISVFLPK-HTMSE----------GIMTMRQDILTSLNKRFAHTKENRKMVLATILDPRFKNFAYDDRELASTAKQWLKNECLILASAERSEEVVEPPSKRPRVETDQAHPGSSTSRLWDLFSDVVSEPALQTNSSIIGNVNDAVDAMIALYLSSAALPRTENPYVWWNSNKLLFPYLATLSRRYLSAPASSVPSEQLFSGAWQIFSDRRGSLTAGKGEMLLLLKYNLPQFSF 2421
            TS +WN+F++    ++K IC  C  ++SRG   + +  TS L++HL+  H     +                 A    P   E    +  D    F  +   A      IAE +ALD+QP+S V+NVGF R++   +P+Y++PS+ YFS T IP M+E ++  +   +    S     T+  W   S +   L+LTAHWVT         +     A+L  S I+  +  D      L+ L +  I    + + +  +  + I K    ++  S+ CF HT+ L++N++I SQR V+++L+I+R    +   S  A++ L++LQ    +P+  L+QDV ++WN +  ML  L+EQK+ +   + E     L    QW ++  +   L PF+ A++E+S    ++S  +P  H ++           GI TM + +  ++  R + T  + + + AT+LDPR+K   + + E A   KQ L  E  IL+S      ++   +K    +++          +W L +++    AL+             + ++  YL    L    +P  +WN  K  +P LA L+ R+L  P S +PSE+LF+ A +  +  +  L     E L+ LK NLP   F
Sbjct:  539 TSKLWNHFSICSADSTKVICMHCGRTISRGKKPT-NLGTSCLLRHLQRFHSNVLQN--------NSVSETLRPADSQTPVNTELAASSFEDTTDKFSDSHPVAKKITSLIAEMIALDLQPYSFVNNVGFNRLLEYLQPQYSLPSASYFSRTAIPDMYENVKQIIVSHLKEAESGVIHFTAGIWMS-SQTREYLTLTAHWVTFESSFRPHCENHHCSALLHVSQIDCDY-NDVSVQKHLEYLWESWIASCGLQIGITVTDNHSIAKTLNESEHSSVQCFGHTVDLIVNEAIKSQRMVQNLLSIARKICERVHRSTKAKEKLAELQKEYDLPQHHLIQDVPSKWNTSFHMLDRLIEQKRAIDEMSIECSFRELISCDQWEVMQSVCHALKPFEAASREMSMHMATLSQVIPMIHILNRKIEMLFEETMGIDTMLKSLKEAMVCRLSSTLHDPRYIFATLLDPRYKASLFSEEE-AEEYKQGLIRELEILSSTSDDALILNGCNKSSSPKSN------GEENIWSLMANIKRSKALK---------EKLPEDIVFAYLEEEVLEHNCDPLTYWNLKKSAWPVLAKLAVRFLGCPPSIIPSERLFNTANENCNFNQNRLMMEHFEQLIFLKVNLPLIYF 1146          

Query:  853 LDRRQPFEFNDKRALDWNKTIAEFMALDVQPFSVVDNVGFRRIIAKAEPRYTIPSSRYFSSTLIPAMHEKIQNKV-REMVSSQPS-TSLTSDAWSDPSISVALLSLTAHWVT------EDFQRKQAILAASPIEESHTGDYLGGMLLKILGDYTIEKSAVHVLLRDSGA-NMIKASRVADIDSISCFAHTLQLVINDSIMSQRSVKDILAISRSNVGKFRHSVLAQQHLSDLQGSLGVPKKKLVQDVQTRWNATLAMLRSLVEQKQVLGAYATEHKLTN----LDAHQWTLISHIIDTLSPFKDATKEVSDSQTSISVFLPK-------------HTMSEG---------IMTMRQDILTSLNKRFAHTKENRKMVLATILDPRFKNFAYDDRELASTAKQW----LKNECLILASAERSEEVVEPPSKRPRVETDQAHPGSSTSRLWDLFSDVVSEPALQTNSSIIGNVNDAVDAMIALYLS-SAALPRTENPYVWWNSNKLLFPYLATLSRRYLSAPASSVPSEQLFS 2322
            L+ +  +  N  +A  WN+ IAE +     P+S + +  F++ +A+A+P+Y +PS  +FS+  +P ++E +  KV  E+  S+ +   LT+  WS   +SV  L+LTAHW        +  QRK A+L      + +    +   L++ +  +    +        SG  N+I A + A+ +SI CF HTL L++ D + +   +  +L ++R     F HS  A++ LS+LQ    +PK+ L  +    W +T  ML+ L+EQ++ +  Y   HKL      L +  W+L++ ++D L PF+  T+EV+ S + +S  LP+             H  S+G           T++      +N+ F    +  + V++T+LDPRFK          S    W    +K    I++S+ R    ++  S  P              RL  L +   +  +L T S        +   M+  YL  +  +   E+P V+W   K L+P L  L+  YL+ P SS+ ++++FS
Sbjct:  453 LNIKGKYAPNHPKAQSWNRNIAELVCGMALPYSFITSKAFKKFMARADPKYCVPSKSFFSAKAVPQLYEAVCEKVMSELKRSECAHVHLTTHVWSG-GLSVDYLALTAHWSVLNPEDLQSIQRKNAVLCTKGFPKDYIDGSIQQELIRQMNLWLSPNALSPGFFISSGNFNLIHAIKSANFNSIPCFTHTLNLLVMDFLQNNHYISSMLEVARKVCSHFIHSARARRILSELQFQNHLPKQPLKSETLPHWTSTFYMLQRLLEQQRAIEEYLGSHKLETAELRLTSSNWSLMACLVDLLQPFEMVTREVNASGSCLSQVLPEVRYLHIFLKQIRGHFESKGDVNGVVLTDSFTLKFSSDFGINEMF----QREEYVVSTLLDPRFKGRIEAILPPGSDIDHWKQILVKKVKEIMSSSSRPVSHLKDSSSEP-------------DRLASLLASKSTGASLSTES-------HSACVMVEKYLQDNQTIGAKEDPLVYWEKRKCLWPALTKLAFMYLTCPPSSIFAQRVFS 957          

Query:  643 SKAICNLCNVSLSRGGNESKSFTTSNLVQHLRSKHVVAFADFXXXXXXXXXXXXXXXTASIPRPATIEALLDRRQPFEFNDKRAL-----DWNKTIAEFMALDVQPFSVVDNVGFRRIIAKAEPRYTIPSSRYFSSTLIPAMHEKIQNKVREMVSSQPSTSLTSDAWSDPSISVALLSLTAHWVTEDFQRKQAILAASPIEESHTGDYLGGMLLKILGDYTIEKSAVHVLLRDSGANMIKASRVADIDSISCFAHTLQLVINDSIMSQRSVKDILAISRSNVGKFRHSVLAQQHLSDLQGSLGVPKKKLVQDVQTRWNATLAMLRSLVEQKQVLGAYATEHKLTNLDAHQ--WTLISHIIDTLSPFKDATKEVSDSQTS--------ISVFLPKHTM-----SEGIMTMRQDILTSLNKRFAHTKENRKMVLATILDPRFKNFAYDDRELASTAKQWLKNECLILASAERSEEVV---EPPSKRPRVETDQAHPGSSTSRLWDLFSDVVSEPALQTNSSIIGNVNDAVDAMIALYLSSAALPRTENPYVWWNSNKLLFPYLATLSRRYLSAPASSVPSEQLFSGAWQIFSDRRGSLTAGKGEMLLLLKYN 2403
            +K IC LC V LS  GN      T+NL QHL  KH   + D                 A +    +IE++     P E   +  +        + +A+F+  D+ P  +++  GF +++A  +P Y +P+  + + T++  M+ +++ KV E+V +    S++ D W   S +++ L+LT H+V E F+ +  +L++  + E  +   L  +LL    ++ I  +  + +  +S +  +  S V     + C    L+  I ++++   +++  L   R        S    + +S     L V  K  ++D  T+W +   +L+S+V+            + +++   Q  W+++  ++D L P   AT   +  Q +        I+  L KH       S+   T+++ I   L+ ++A    N+ + LA  LDPRF+   +  +         LK E   LA  +  E      EP + +P ++  +   G        L  D+ S       +S +  VN   +  I+ + +S A    ++P  WW  +   +P LA  +R+ L+ PA+SVP+  LF+ A      +R +LTA   ++L+ L  N
Sbjct:  170 TKIICKLCGVRLSYSGN------TTNLRQHLIYKHRRQYNDLVGTQG-----------AVVDPHKSIESV----SPCELASRAIVAPTVGRTTRAVADFIVRDLMPLEIIEGEGFIQMLAILDPNYKLPAISFLAHTILQEMYIQVKVKVVELVKNLQECSISLDFWKH-SGALSYLTLTIHYVDEGFESRNIMLSSRAVAEDLSEGNLTSVLLDAAEEWGIRDNTFYAVGLNSSSVKVATSNVG-WRPLPCVGQVLRGCI-ETVLQHHTIQSTLDRFRKLTAFVCSSPTQIEEMSTHGPVLKVHLKMFLRD-GTKWYSIYTLLQSIVDHSNYFKNLTETIRESDIVLQQDDWSVLQDVVDILKPLAIATSTFTKDQFAGLSLVKPVITSLLYKHLAPNEWDSDFCKTIKKAIHEDLSFKYADHDVNQVLNLACALDPRFRGLDFLSQPDRVETLHLLKLEASNLAKLQTPEHTCVTPEPLNAKPPIKKVKQDSGIEF-----LLGDLCS-----VRNSSVSTVNQQAEQEISSFQTSEASSLCQDPLQWWKMHHTQYPLLARAARKLLAIPATSVPTNWLFTDAGLAVYRKRSALTAENVDLLVFLNGN 744          

Query:  643 SKAICNLCNVSLSRGGNESKSFTTSNLVQHLRSKHVVAFADFXXXXXXXXXXXXXXXTASIPRPATIEALLDRRQPFEFNDKRAL-----DWNKTIAEFMALDVQPFSVVDNVGFRRIIAKAEPRYTIPSSRYFSSTLIPAMHEKIQNKVREMVSSQPSTSLTSDAWSDPSISVALLSLTAHWVTEDFQRKQAILAASPIEESHTGDYLGGMLLKILGDYTIEKSAVHVLLRDSGANMIKASRVADIDSISCFAHTLQLVINDSIMSQRSVKDILAISRSNVGKFRHSVLAQQHLSDLQGSLGVPKKKLVQDVQTRWNATLAMLRSLVEQKQVLGAYATEHKLTNLDAHQ--WTLISHIIDTLSPFKDATKEVSDSQTS--------ISVFLPKHTM-----SEGIMTMRQDILTSLNKRFAHTKENRKMVLATILDPRFKNFAYDDRELASTAKQWLKNECLILASAERSEEVV---EPPSKRPRVETDQAHPGSSTSRLWDLFSDVVSEPALQTNSSIIGNVNDAVDAMIALYLSSAALPRTENPYVWWNSNKLLFPYLATLSRRYLSAPASSVPSEQLFSGAWQIFSDRRGSLTAGKGEMLLLLKYN 2403
            +K IC LC V LS  GN      T+NL QHL  KH   + D                 A +    +IE++     P E   +  +        + +A+F+  D+ P  +++  GF +++A  +P Y +P+  + + T++  M+ +++ KV E+V +    S++ D W   S +++ L+LT H+V E F+ +  +L++  + E  +   L  +LL    ++ I  +  + +  +S +  +  S V     + C    L+  I ++++   +++  L   R        S    + +S     L V  K  ++D  T+W +   +L+S+V+            + +++   Q  W+++  ++D L P   AT   +  Q +        I+  L KH       S+   T+++ I   L+ ++A    N+ + LA  LDPRF+   +  +         LK E   LA  +  E      EP + +P ++  +   G        L  D+ S       +S +  VN   +  I+ + +S A    ++P  WW  +   +P LA  +R+ L+ PA+SVP+  LF+ A      +R +LTA   ++L+ L  N
Sbjct:  284 TKIICKLCGVRLSYSGN------TTNLRQHLIYKHRRQYNDLVGTQG-----------AVVDPHKSIESV----SPCELASRAIVAPTVGRTTRAVADFIVRDLMPLEIIEGEGFIQMLAILDPNYKLPAISFLAHTILQEMYIQVKVKVVELVKNLQECSISLDFWKH-SGALSYLTLTIHYVDEGFESRNIMLSSRAVAEDLSEGNLTSVLLDAAEEWGIRDNTFYAVGLNSSSVKVATSNVG-WRPLPCVGQVLRGCI-ETVLQHHTIQSTLDRFRKLTAFVCSSPTQIEEMSTHGPVLKVHLKMFLRD-GTKWYSIYTLLQSIVDHSNYFKNLTETIRESDIVLQQDDWSVLQDVVDILKPLAIATSTFTKDQFAGLSLVKPVITSLLYKHLAPNEWDSDFCKTIKKAIHEDLSFKYADHDVNQVLNLACALDPRFRGLDFLSQPDRVETLHLLKLEASNLAKLQTPEHTCVTPEPLNAKPPIKKVKQDSGIEF-----LLGDLCS-----VRNSSVSTVNQQAEQEISSFQTSEASSLCQDPLQWWKMHHTQYPLLARAARKLLAIPATSVPTNWLFTDAGLAVYRKRSALTAENVDLLVFLNGN 858          

Query:  601 SSIWNYFTVSP------LINSKAICNLCNVSLSRGGNESKSFTTSNLVQHLRSKHVVAFADFXXXXXXXXXXXXXXXTASIPRPAT----IEALLDRRQPFEFNDKRALDWNKTIAEFMALDVQPFSVVDNVGFRRIIAKAEPRYTIPSSRYFSSTLIPAMHEKIQNKVREMVSSQPS----TSLTSDAWSDPSISVALLSLTAHWVTED----FQRKQAILAASPIEESHTGDYLGGMLLKILGDYTIEKSAVHVLLRDSGANMIKASRVADID-SISCFAHTLQLVINDSIMSQRSVKDILAISRSNVGKFRHSVLAQQHLSDLQGSLGVPKKKLVQDVQTRWNATLAMLRSLVEQKQVLGAYATE----HKLTNLDAHQWTLISHIIDTLSPFKDATKEVSDSQ-TSISVFLP------------KHTMSEGIMTMRQDILTSLNKRFAHTKE-NRKMVLATILDPRFKNFAYDDRELASTAKQWLKN------ECLILASAE--RSEEVV-----EPPSKRPRVETDQAHPGSS-TSRLWDLFSDV-VSEPALQTNSSIIGNVNDAVDAMIALYLSSAALPRTENPYVWWNSNKLLFPYLATLSRRYLSAPASSVPSEQLFSGAWQIFSDRRGSLTAGKGEMLLLLKYNLPQFSFNC 2427
            S +W YF          L   K  C +C   ++  GN      TSNL  HL   H   F +F K + E+       + + + +P +    ++  L  +    F +K+ L+   ++   +   + P S++D   F+ ++  AEPRY +P  +Y  S ++P  +    N +REMV    +      +++D W   + + + ++L+ ++++             L    + E +  + +  +L +   ++ I  + V     D   +++KA  + DI   + C   T  + I  +    + +  +L+  R  V  F+ S +A   L + Q    +    L+ D  + W +TL ML+ L EQ+  +     E    H L  L+A +W  I  ++D L PFK   + +S S+  +IS+  P            K T  + I   ++ I   L+  +  T E +  + +AT LDPR+K   +    L++  +  ++N      +C I    E  ++EE V     EPP K+  + +    P SS  S L ++F     SE   + ++ ++  +++        + S   L   E+P  WW+    LFP L  + ++Y     + V  E+LF+ +  + + +R  L     +  + L  N    + NC
Sbjct:   23 SKVWKYFGFDTNAEGCILQWKKIYCRICMAQIAYSGN------TSNLSYHLEKNHPDEFCEFVKSNTEQMREAFATAFSKL-KPESSQQVVQETLIMKNTHSFENKKHLELTSSVISLICEGMYPASILDEPTFKNLLKTAEPRYEVPMRKYICSRVLPEKY----NAIREMVLKDLNDILWCGISTDMWKSVTQNRSYVTLSVYFMSTGPSNCLSVNSRCLKTFEVPEENKAETITRVLYETFIEWGI-SAKVFGATTDFSKDIVKACSLLDIPVDMPCLGQTFDMGIQQAFQLPK-LSSLLSRCRKLVEYFQQSSIAMYMLCEKQKQQNLFPCMLISDRVSWWGSTLVMLQRLKEQQFTIAGVLVEDSNNHHLM-LEASEWNTIEGLVDLLQPFKQVAEMLSVSKYPTISMVKPLLHMLLNTSLNIKETDPKEISMAKEVIAKVLSSTYQQTPEIDMFLNVATFLDPRYKKLPF----LSAFERAQVENRVIEEAKCFIDKGKENIKNEEKVFTISEEPPMKK--MASSTPPPTSSINSMLAEIFCQSGSSEDQEEWHAQVVEELSN--------FKSQKVLGLNEDPLKWWSDRLTLFPLLPKVLQKYWCIRPTRVFPERLFNSSANVVNSKRNRLAPAHVDEQIFLYEN----THNC 651          

Query:  571 LFEEMSKQLTSSIWNYFTVSPLINSKAICNLCNVSLSRGGNESKSFTTSNLVQHLRSKHVVAFADFXXXXXXXXXXXXXXXTASIPRPATIE-----ALLDRRQPFEFNDKRALDWNKTIAEFMALDVQPFSVVDNVGFRRIIAKAEPRYTIPSSRYFSSTLIPAMHEKIQNKVREMVSSQPS--TSLTSDAWSDPSISVALLSLTAHWVT---------EDFQRKQAILAASPIEESHTGDYLGGMLLKILGDY-----TIEKSAVHVLLRDSGANMIKASRVADIDSISCFAHTLQLVINDSIMSQRSVKDILAISRSNVGKFRHSVLAQQHLSDLQGSLGVPKKKLVQDVQTRWNATLAMLRSLVEQKQVLGAYATEHKLTNL-DAHQWTLISHIIDTLSPFKDATKEVSDSQTSISVFLPK-HTMSE----------GIMTMRQDILTSLNKRFAHTKENRKMVLATILDPRFKNFAYDDRELASTAKQWLKNECLILASAERSEEVVEPPSKRPRVETDQAHPGSSTSRLWDLFSDVVSEPALQTNSSIIGNVNDAV-DAMIALYLSSAALPRTENPYVWWNSNKLLFPYLATLSRRYLSAPASSVPSEQLFSGAWQIFSDRRGSLTAGKGEMLLLLKYNLPQFSFN 2424
            +F   SK+ TS +WN+F++    ++K +C  C  ++SRG  +  +  TS L++HL+  H     +                +  I RP  IE     +  D  + F  +   A      IAE +ALD+QP+S+VDNVGF R++   +P+Y++PS  YFS T IP M++ ++  +   +    S     TS  W   S +   L+LTAHWVT         ED     A+L  S I+     DY G  + K L  +     T     + + + D+  ++ K     +  S+ CF+HT+ L+++++I SQR V+++L+I+R    +   S  A++ L++LQ    +P+ +L+QDV ++W+ +  ML  L+EQK+ +   + E     L    QW ++  +   L PF  A++E+S   +++S  +P  H +S           GI TM + +  ++  R + T  + + + AT+LDPR+K   + + E A   +Q L  E  IL S   SE+             D   P            D  +E +L + + I  +  + + + M+  YL    L  + +P  +WN  +  +P L+TL+ R+L  P S+VPSE+LFS      S  +  L     E L+ LK NLP   F 
Sbjct:  551 VFPTNSKK-TSKLWNHFSICSADSTKVVCLHCGRTISRG-KKPTNLGTSCLLRHLQRFHGHVLKN-------DVSEATLSRSPGIRRPLGIELSGPSSFRDSTEKFYDSHPVAKKITSLIAEMIALDLQPYSLVDNVGFNRLLEYLKPQYSLPSPSYFSRTAIPGMYDNVKQIIMSHLKEAESGVVHFTSGIWMS-SQTREYLTLTAHWVTFASAVRPHCED-HHCSALLDVSQID----CDYSGNSIQKQLECWWEAWVTSIGLQIGITVTDN-PSIGKMLSEGEHSSVQCFSHTVNLIVSEAIKSQRMVQNLLSIARKLCERVHRSPRAREKLAELQKEYELPQHQLIQDVPSKWSTSFHMLERLIEQKRAVNEVSIECNFRELISCDQWEVMQSVCHVLRPFDAASREMSAHMSTLSQVIPMIHILSRKVEMLFGETMGIDTMLKSLKEAMASRLSATLHDPRYIFATLLDPRYKASLFTEEE-AEQYRQDLIRELEILNST--SEDTATSNG------CDSGSP----------LKDTGTEESLWSLAPIKRDQREKLPEDMVLAYLEEEVLEHSCDPLTYWNLKRSSWPGLSTLAVRFLGCPPSTVPSEKLFSTPMDAGSFGQPRLMMEHFEKLIFLKVNLPLICFQ 1167          

Query:  904 NKTIAEFMALDVQPFSVVDNVGFRRIIAKAEPRYTIPSSRYFSSTLIPAMHEKIQNKV---REMVSSQPSTSLTSDAWS-DPSISVALLSLTAHWV------------TEDFQRKQAILAASPIEESHTGDYLGGMLLKILGD-----YTIEKSAVHVLLRDSGANMIKASRVADIDSISCFAHTLQLVINDSIMSQRSVKDILAISRSNVGKFRHSVLAQQHLSDLQGSLGVPKKKLVQDVQTRWNATLAMLRSLVEQKQVLGAYATEHKLTN-----LDAHQWTLISHIIDTLSPFKDATKEVSDSQTSISVFLPK-HTMSEGIMTMRQD-----ILTSLN------------KRFAHTKENRKMVLATILDPRFKNFAYD------DRELASTAKQWLKNE-CLILASAERSEEVVEPPSKRP--RVETDQ-AHPGSSTSRLWDLFSDVVSEPALQTNSSIIGNVNDAVDAMIALYLSSAALPRTENPYVWWNSNKLLFPYLATLSRRYLSAPASSVPSEQLFSGAWQIFSDRRGSLTAGKGEMLLLLKYNLPQFSFN 2424
            ++ + + +  D+ P++      F+R +    P Y +PS  YF +  +P +++ ++ K+    E V SQ    LT+D W+ DPS    ++  T HWV            T +F RK A+L  + + +    D L   +L+ L D      +        ++ D+ +N++ A +      + CF H L +VI D     +S++++L  +R     F HSV A+Q L + Q    +P K L QD    W +T  ML+ L+E       Y+  H L       L + QWTL++++ D L PF++AT+ VS   T ++  LP  H +   +  +R+D     I  +LN               +   +++  +LAT+LDP FKN   D      D E   T KQ L  E C  + S+  + ++    +  P  R+ TD        TS    L S      A+ + SS++      VD       S   L   ++P V+W     ++P L  ++ +YLS P  S  SE +F+        +  ++     E L+ LK NL   +++
Sbjct:  414 SQAVIQMIVEDLHPYNYFSTPAFQRFLQIVAPDYRLPSETYFFTKAVPQLYDSVREKIFLTLENVQSQ-KIHLTADIWTHDPSTDYFIV--TVHWVSLETASSPSNGGTPNF-RKWAVLCVTGLAK----DCLITNILQELNDQIGLWLSPNFLTPSFIVSDNSSNVVHAIKGGGFTHVPCFLHCLNIVIQDFFCEHKSIENMLVAARKTCHHFSHSVKARQILQEFQNDHQLPWKNLKQDETGHWISTFYMLKWLLEH-----CYSVHHSLGRASGVVLTSLQWTLMTYVCDILKPFEEATQRVSVKTTGLNQVLPLIHHLLFSLQRLREDFQVRGITQALNLVDSLSLKLESDALLSAMLKSKHCILATLLDPCFKNSLEDFFPQGADLE---TYKQILAEEVCNYMESSPGACQISSSETSGPLVRLGTDSFTSIKEGTSSAGSLDSSAAGSVAVGSKSSLLPAAVAVVDEYFKEKYSE--LSGGDDPLVYWQRKVSIWPALTQVAIQYLSCPMCSWQSECMFTTNSHFHPKQIMNMDFDNIEQLIFLKMNLENVNYD 956          

Query:  440 EWLTLEICREYMRGECLRDEFSCRYAHPAKNLETQSGRVICCYDYLK 580
            +WLTLE+CRE+ RG C R +  C++AHP+K+ + ++GRVI C+D LK
Sbjct:   12 KWLTLEVCREFQRGTCSRPDTECKFAHPSKSCQVENGRVIACFDSLK 58          

Query:  440 EWLTLEICREYMRGECLRDEFSCRYAHPAKNLETQSGRVICCYDYLK 580
            +WLTLE+CRE+ RG C R +  C++AHP+K+ + ++GRVI C+D LK
Sbjct:   12 KWLTLEVCREFQRGTCSRPDTECKFAHPSKSCQVENGRVIACFDSLK 58          

Query:  440 EWLTLEICREYMRGECLRDEFSCRYAHPAKNLETQSGRVICCYDYLK 580
            +WLTLE+CRE+ RG C R +  C++AHP+K+ + ++GRVI C+D LK
Sbjct:   12 KWLTLEVCREFQRGTCSRPDTECKFAHPSKSCQVENGRVIACFDSLK 58          

Query:  452 LEICREYMRGECLRDEFSCRYAHPAKN--LETQSGRVICCYDYLK 580
            LE+CREY RG C R E  CR+AHPA +  ++T    V  C DY+K
Sbjct:  181 LEVCREYQRGNCNRGENDCRFAHPADSTMIDTNDNTVTVCMDYIK 225          

Query:  571 LFEEMSKQLTSSIWNYFTVSPLINSKAICNLCNVSLSRGGNESKSFTTSNLVQHLRSKHVVAFADFXXXXXXXXXXXXXXXTASIPRPATIE-----ALLDRRQPFEFNDKRALDWNKTIAEFMALDVQPFSVVDNVGFRRIIAKAEPRYTIPSSRYFSSTLIPAMHEKIQNKVREMVSSQPS--TSLTSDAWSDPSISVALLSLTAHWVT---------EDFQRKQAILAASPIEESHTGDYLGGMLLKILGDY-----TIEKSAVHVLLRDSGANMIKASRVADIDSISCFAHTLQLVINDSIMSQRSVKDILAISRSNVGKFRHSVLAQQHLSDLQGSLGVPKKKLVQDVQTRWNATLAMLRSLVEQKQVLGAYATEHKLTNL-DAHQWTLISHIIDTLSPFKDATKEVSDSQTSISVFLPK-HTMSE----------GIMTMRQDILTSLNKRFAHTKENRKMVLATILDPRFKNFAYDDRELASTAKQWLKNECLILASAERSEEVVEPPSKRPRVETDQAHPGSSTSRLWDLFSDVVSEPALQTNSSIIGNVNDAV-DAMIALYLSSAALPRTENPYVWWNSNKLLFPYLATLSRRYLSAPASSVPSEQLFSGAWQIFSDRRGSLTAGKGEMLLLLKYNLPQFSFN 2424
            +F   SK+ TS +WN+F++    ++K +C  C  ++SRG  +  +  TS L++HL+  H     +                +  I RP  IE     +  D  + F  +   A      IAE +ALD+QP+S+VDNVGF R++   +P+Y++PS  YFS T IP M++ ++  +   +    S     TS  W   S +   L+LTAHWVT         ED     A+L  S I+     DY G  + K L  +     T     + + + D+  ++ K     +  S+ CF+HT+ L+++++I SQR V+++L+I+R    +   S  A++ L++LQ    +P+ +L+QDV ++W+ +  ML  L+EQK+ +   + E     L    QW ++  +   L PF  A++E+S   +++S  +P  H +S           GI TM + +  ++  R + T  + + + AT+LDPR+K   + + E A   +Q L  E  IL S   SE+             D   P            D  +E +L + + I  +  + + + M+  YL    L  + +P  +WN  +  +P L+TL+ R+L  P S+VPSE+LFS      S  +  L     E L+ LK NLP   F 
Sbjct:  551 VFPTNSKK-TSKLWNHFSICSADSTKVVCLHCGRTISRG-KKPTNLGTSCLLRHLQRFHGHVLKN-------DVSEATLSRSPGIRRPLGIELSGPSSFRDSTEKFYDSHPVAKKITSLIAEMIALDLQPYSLVDNVGFNRLLEYLKPQYSLPSPSYFSRTAIPGMYDNVKQIIMSHLKEAESGVVHFTSGIWMS-SQTREYLTLTAHWVTFASAVRPHCED-HHCSALLDVSQID----CDYSGNSIQKQLECWWEAWVTSIGLQIGITVTDN-PSIGKMLSEGEHSSVQCFSHTVNLIVSEAIKSQRMVQNLLSIARKLCERVHRSPRAREKLAELQKEYELPQHQLIQDVPSKWSTSFHMLERLIEQKRAVNEVSIECNFRELISCDQWEVMQSVCHVLRPFDAASREMSAHMSTLSQVIPMIHILSRKVEMLFGETMGIDTMLKSLKEAMASRLSATLHDPRYIFATLLDPRYKASLFTEEE-AEQYRQDLIRELEILNST--SEDTATSNG------CDSGSP----------LKDTGTEESLWSLAPIKRDQREKLPEDMVLAYLEEEVLEHSCDPLTYWNLKRSSWPGLSTLAVRFLGCPPSTVPSEKLFSTPMDAGSFGQPRLMMEHFEKLIFLKVNLPLICFQ 1167          

Query:  598 TSSIWNYFTVSPLINSKAICNLCNVSLSRGGNESKSFTTSNLVQHLRSKHVVAFADFXXXXXXXXXXXXXXXTASIPRPATIEA---LLDRRQPFEFNDKRALDWNKTIAEFMALDVQPFSVVDNVGFRRIIAKAEPRYTIPSSRYFSSTLIPAMHEKIQNKVREMVSSQPSTSL--TSDAWSDPSISVALLSLTAHWVT--------EDFQRKQAILAASPIEESHTGDYLGGMLLKILGDY-----TIEKSAVHVLLRDSGANMIKASRVADIDSISCFAHTLQLVINDSIMSQRSVKDILAISRSNVGKFRHSVLAQQHLSDLQGSLGVPKKKLVQDVQTRWNATLAMLRSLVEQKQVLGAYATEHKLTNL-DAHQWTLISHIIDTLSPFKDATKEVSDSQTSISVFLP-------------KHTMSEGIMTMRQDILTSLNKRFAHTKENRKMVLATILDPRFKNFAYDDRELASTAKQWLKNECLILASAERSEEVVEPPSKRPRVETDQAHPGSSTS---RLWDLFSDVVSEPALQTNSSIIGNVNDAVDAMIALYLSSAALPRTENPYVWWNSNKLLFPYLATLSRRYLSAPASSVPSEQLFSGAWQIFSDRRGSLTAGKGEMLLLLKYNLPQFSF 2421
            TS +WN+F++    ++K +C  C  ++SRG  +  +  TS L++HL+  H         +++  + A        +PR   +       D  + F  +   A      IAE +ALD+QP+S VDNVGF R++   +P+Y++P+  YFS T IP M++ ++  +   +    S  +  TS  W   + +   L+LTAHWV+         D     A+L  S ++     DY G  + K L  +     T     V + + D+ A++ K     +  S+ CF+HT+ L+++++I SQR V+++L+++R    +   S  A++ L++LQ    +P+  L+QDV ++W+ +  ML  L+EQK+ +   + E     L    QW ++  +   L PF+ A++E+S   +++S  +P             + TM  GI TM + +  ++  R + T  + + V AT+LDPR+K   + + E A   KQ L  E  ++ S   SE+V    S R     D   P   ++    LW L + V  +   +             +AM+  YL    L  + +P  +WN  K  +P L+ L+ R+L  P S VPSE+LF+   +  S  +  L     E L+ LK NLP   F
Sbjct:  560 TSKLWNHFSICSADSTKVVCLHCGRTISRG-KKPTNLGTSCLLRHLQRFHSNVL-----KTEVSETARPSSPDTRVPRGTELSGASSFDDTNEKFYDSHPVAKKITSLIAEMIALDLQPYSFVDNVGFNRLLEYLKPQYSLPAPSYFSRTAIPGMYDNVKQIIMSHLKEAESGVIHFTSGIWMS-NQTREYLTLTAHWVSFESPARPRCDDHHCSALLDVSQVD----CDYSGNSIQKQLECWWEAWVTSTGLQVGITVTDN-ASIGKTLNEGEHSSVQCFSHTVNLIVSEAIKSQRMVQNLLSLARKICERVHRSPKAKEKLAELQREYALPQHHLIQDVPSKWSTSFHMLERLIEQKRAINEMSVECNFRELISCDQWEVMQSVCRALKPFEAASREMSTQMSTLSQVIPMVHILNRKVEMLFEETM--GIDTMLRSLKEAMVSRLSATLHDPRYVFATLLDPRYKASLFTEEE-AEQYKQDLIRELELMNST--SEDVAA--SHR----CDAGSPSKDSAAEENLWSLVAKVKKKDPREK----------LPEAMVLAYLEEEVLEHSCDPLTYWNLKKASWPGLSALAVRFLGCPPSIVPSEKLFNTPTENGSLGQSRLMMEHFEKLIFLKVNLPLIYF 1169          

Query:  904 NKTIAEFMALDVQPFSVVDNVGFRRIIAKAEPRYTIPSSRYFSSTLIPAMHEKIQNKV---REMVSSQPSTSLTSDAWS-DPSISVALLSLTAHWV------------TEDFQRKQAILAASPIEESHTGDYLGGMLLKILGD-----YTIEKSAVHVLLRDSGANMIKASRVADIDSISCFAHTLQLVINDSIMSQRSVKDILAISRSNVGKFRHSVLAQQHLSDLQGSLGVPKKKLVQDVQTRWNATLAMLRSLVEQKQVLGAYATEHKLTN-----LDAHQWTLISHIIDTLSPFKDATKEVSDSQTSISVFLPK-HTMSEGIMTMRQD-----ILTSLN------------KRFAHTKENRKMVLATILDPRFKNFAYD------DRELASTAKQWLKNE-CLILASAERSEEVVEPPSKRP--RVETDQ-AHPGSSTSRLWDLFSDVVSEPALQTNSSIIGNVNDAVDAMIALYLSSAALPRTENPYVWWNSNKLLFPYLATLSRRYLSAPASSVPSEQLFSGAWQIFSDRRGSLTAGKGEMLLLLKYNLPQFSFN 2424
            ++ + + +  D+ P++      F+R +    P Y +PS  YF +  +P +++ ++ K+    E V SQ    LT+D W+ DPS    ++  T HWV            T +F RK A+L  + + +    D L   +L+ L D      +        ++ D+ +N++ A +      + CF H L +VI D     +S++++L  +R     F HSV A+Q L + Q    +P K L QD    W +T  ML+ L+E       Y+  H L       L + QWTL++++ D L PF++AT+ VS   T ++  LP  H +   +  +R+D     I  +LN               +   +++  +LAT+LDP FKN   D      D E   T KQ L  E C  + S+  + ++    +  P  R+ TD        TS    L S      A+ + SS++      VD       S   L   ++P V+W     ++P L  ++ +YLS P  S  SE +F+        +  ++     E L+ LK NL   +++
Sbjct:  414 SQAVIQMIVEDLHPYNYFSTPAFQRFLQIVAPDYRLPSETYFFTKAVPQLYDSVREKIFLTLENVQSQ-KIHLTADIWTHDPSTDYFIV--TVHWVSLETASSPSNGGTPNF-RKWAVLCVTGLAK----DCLITNILQELNDQIGLWLSPNFLTPSFIVSDNSSNVVHAIKGGGFTHVPCFLHCLNIVIQDFFCEHKSIENMLVAARKTCHHFSHSVKARQILQEFQNDHQLPWKNLKQDETGHWISTFYMLKWLLEH-----CYSVHHSLGRASGVVLTSLQWTLMTYVCDILKPFEEATQRVSVKTTGLNQVLPLIHHLLFSLQRLREDFQVRGITQALNLVDSLSLKLESDALLSAMLKSKHCILATLLDPCFKNSLEDFFPQGADLE---TYKQILAEEVCNYMESSPGACQISSSETSGPLVRLGTDSFTSIKEGTSSAGSLDSSAAGSVAVGSKSSLLPAAVAVVDEYFKEKYSE--LSGGDDPLVYWQRKVSIWPALTQVAIQYLSCPMCSWQSECMFTTNSHFHPKQIMNMDFDNIEQLIFLKMNLENVNYD 956          

Query:  904 NKTIAEFMALDVQPFSVVDNVGFRRIIAKAEPRYTIPSSRYFSSTLIPAMHEKIQNKV---REMVSSQPSTSLTSDAWS-DPSISVALLSLTAHWVT------------EDFQRKQAILAASPIEESHTGDYLGGMLLKILGDYTIEKSAVHVLL-----RDSGANMIKASRVADIDSISCFAHTLQLVINDSIMSQRSVKDILAISRSNVGKFRHSVLAQQHLSDLQGSLGVPKKKLVQDVQTRWNATLAMLRSLVEQKQVLGAYATEHKLTN-----LDAHQWTLISHIIDTLSPFKDATKEVSDSQTSISVFLPK-HTMSEGIMTMRQD-----ILTSLN------------KRFAHTKENRKMVLATILDPRFKNFAYD------DRELASTAKQWLKNECLILASAERSEEVVEPPSKRPRVETDQAHPGSSTSRLWD-------LFSDVVSEPALQTNSSIIGNVNDAVDAMIALYLSSAALPRTENPYVWWNSNKLLFPYLATLSRRYLSAPASSVPSEQLFSGAWQIFSDRRGSLTAGKGEMLLLLKYNLPQFSFN 2424
            ++ I + +  D+ P++      F+R +    P Y +PS  YF +  +P +++ ++ K+    E V SQ    LT D W+ DPS    ++  T HWV+             DF RK A+L  + + +    D L   +L+ L D      + + L+      D+ +N++ A +      + CF H L +VI D     +S++++L  +R     F HSV A+Q L + Q    +P K L QD    W +T  ML+ L+E       Y+  H L       L + QWTL++++ D L PF++AT++VS     ++  LP  H +   +  +R+D     I  +LN               +   +++  +LAT+LDP FKN   D      D E   T KQ+L  E  +    E S E+ + P+      +      S TS L +       + S  V   AL + S +  +    VD       S       ++P ++W     ++P L  ++ +YLS P  S  SE +F+        +  SL     E L+ LK NL   +++
Sbjct:  411 SQAIIQMIVEDMHPYNYFSTPAFQRFMQIVAPDYRLPSETYFFTKAVPQLYDCVREKIFLTLENVQSQ-KIHLTVDIWTHDPSTDYFIV--TVHWVSLETASFLNNGRIPDF-RKWAVLCVTGLAK----DCLITNILQELNDQIGLWLSPNFLIPSFIVSDNSSNVVHAIKDGGFTHVPCFLHCLNMVIQDFFCEHKSIENMLVAARKTCHHFSHSVKARQILQEFQNDHQLPWKNLKQDETGHWISTFYMLKWLLEH-----CYSVHHSLGRASGVVLTSLQWTLMTYVCDILKPFEEATQKVSVKTAGLNQVLPLIHHLLLSLQKLREDFQVRGITQALNLVDSLSLKLETDTLLSAMLKSKPCILATLLDPCFKNSLEDFFPQGADLE---TYKQFLAEE--VCNYMESSPEICQIPTSEASCPSVTVGADSFTSSLKEGTSSSGSVDSSAVDNVALGSKSFMFPSAVAVVDEYFKEKYSE--FSGGDDPLIYWQRKISIWPALTQVAIQYLSCPMCSWQSECIFTKNSHFHPKQIMSLDFDNIEQLMFLKMNLKNVNYD 954          

Query:  601 SSIWNYFTVSP------LINSKAICNLCNVSLSRGGNESKSFTTSNLVQHLRSKHVVAFADFXXXXXXXXXXXXXXXTASIPRPATIEALLDR---RQPFEFNDKRALDWNKTIAEFMALDVQPFSVVDNVGFRRIIAKAEPRYTIPSSRYFSSTLIPAMHEKIQNKVREMVSSQPSTSLTSDAWSDPSISVALLSLTAHWVT----EDFQRKQAILAASPIEESHTGDYLGGMLLKILGDYTIEKSAVHVLLRDSGANMIKASRVADID-SISCFAHTLQLVINDSIMSQRSVKDILAISRSNVGKFRHSVLAQQHLSDLQGSLGVPKKKLVQDVQTRWNATLAMLRSLVEQKQVLGAYATE----HKLTNLDAHQWTLISHIIDTLSPFKDATKEVSDSQ-TSISVFLP------------KHTMSEGIMTMRQDILTSLNKRFAHTKE-NRKMVLATILDPRFKNFAYDDRELASTAKQWLKNECLILASAERSEEVVEPPSKRPRVETDQAHPGSSTSRLWDLFSDVVSEPALQTNSSI------IGNVND------AVDAMIALYLSSAALPRTENPYVWWNSNKLLFPYLATLSRRYLSAPASSVPSEQLFSGAWQIFSDRRGSL 2361
            S +W YF          L   K  C +C   ++  GN      TSNL  HL   H   F +F K + E+       + + +   ++ +   D    +    ++ K+  +    +   +   + P S+VD   F+ ++  A+PRY +PS +Y S+  IP  +  ++  + + ++      +++D W   + + A ++L AH++              L    + E +T + +  +L ++  ++ I  + V     + G +++KA  + D+   + C  HT    I  +    + +  +L+  R  V  F+ S +A   L + Q    V    LV +  + W +TLAML+ L EQ+ V+     E    H L  L+A +W  I  +++ L PFK   + +S S+  +IS+  P            K T S+ +   ++ I   L+K +  T E +  + +AT LDPR+K   +    L++  +Q ++N   ++  A+   + V+    RP    D+  P      +  L       PA   N+ +       G V D       V   ++ + S   L   E+P  WW+    LFP L  + ++Y    A+ V  E+LF  A  + S +R  L
Sbjct:   23 SKVWKYFGFDTNAEGCILQWKKIYCRICMAQIAYSGN------TSNLSYHLEKNHPEEFCEFVKSNTEQMREAFATAFSKLKPESSQQPGQDALAVKAGHGYDSKKQQELTAAVLGLICEGLYPASIVDEPTFKVLLKTADPRYELPSRKYISTKAIPEKYGAVREVILKELAEATWCGISTDMWRSENQNRAYVTLAAHFLGLGAPNCLSMGSRCLKTFEVPEENTAETITRVLYEVFIEWGI-SAKVFGATTNYGKDIVKACSLLDVAVHMPCLGHTFNAGIQQAFQLPK-LGALLSRCRKLVEYFQQSAVAMYMLYEKQKQQNVAHCMLVSNRVSWWGSTLAMLQRLKEQQFVIAGVLVEDSNNHHLM-LEASEWATIEGLVELLQPFKQVAEMLSASRYPTISMVKPLLHMLLNTTLNIKETDSKELSMAKEVIAKELSKTYQETPEIDMFLNVATFLDPRYKRLPF----LSAFERQQVENR--VVEEAKGLLDKVKDGGYRPA--EDKIFPVPEEPPVKKLMRTSTPPPASVINNMLAEIFCQTGGVEDQEEWHAQVVEELSNFKSQKVLGLNEDPLKWWSDRLALFPLLPKVLQKYWCVTATRVAPERLFGSAANVVSAKRNRL 636          

Query:  601 SSIWNYFTVSPLINSKAICNLCNVSLSRGGNESKSFTTSNLVQHLRSKHVVAFADFXXXXXXXXXXXXXXXTASIPRPATIEALLDRRQPFEFNDKRALDWNKTIAEFMALDVQPFSVVDNVGFRRIIAKAEPRYTIPSSRYFSSTLIPAMHEKIQNKVREMVSSQPSTSLTSDAWSDPSISVALLSLTAHWVTEDFQRKQAILAASPIEESHTGDYLGGMLLKILGDYTIEKSAVHVLLRDSGANMIKASRVADIDSISCFAHTLQLVINDSIMSQRSVKDILAISRSNVGKFRHSVLAQQHLSDLQGSLGVPKKKLVQDVQTRWNATLAMLRSLVEQKQVLGAYATEHKLTN-LDAHQWTLISHIIDTLSPFKDATKEVSDSQTSISVFLPKHTM-----------SEGIMTMRQDILTSLNKRFAHTKENRKMVLATILDPRFKNFAYDDRELASTAKQWLKNECLILASAERS---EEVVEPPSKRPRVETDQAHPGSSTSRLWDLFSDVVSEPALQTNSSIIGNVNDAVDAMIALYLSSAALPRTENPYVWWNSNKLLFPYLATLSRRYLSAPASSVPSEQLFSGAWQIFSDRRGSLTAGKGEMLLLLK 2397
            S++WNYF V+    +KA C LC+  LSRGG++  +F TSNL++HL+S+H   + +F                A  P   T++  L RR+    ++ RA+   + I E+ AL  QP S V+NVGF R++   EPRY +PS RY + T +P +H+ ++  +  ++ +  + S T+D W+     V+L+SLT+ W+ E F  ++AIL       SHT   +  +  ++L  + I K+ VHV+LRD+  NMIKA   A + S+ C AHTLQL +++ +++QRS+ D +A+ R  VG F+HS LA   L D+QG L  P K+L QDVQTRWN+T  ML+SL+EQK+VLG Y +EH+L + L AHQW L+   +  L+PF++ TK+VS      S  +P  T+             G+ TM+  +L ++ KRF+  + N    ++TILDPR+K+  + +   A  AK  LK E  +++ AE      E  EPP+K       QA   S++S L  +F ++  E   Q  ++       A++  +  YL  A  PR ++P  +W  NK+ FP LA ++R+YLSAP SSV SE+LFS    I  + R  LTA   E LL LK
Sbjct:    2 SAVWNYFKVNEDDKTKADCKLCSAKLSRGGSKGSAFNTSNLIKHLKSQHDNEYKEFTL--------------APKPTQPTLQQTLARREKMSRDNPRAVKITQAIIEYTALSDQPLSEVENVGFLRLLHVLEPRYDVPSRRYMTDTELPKLHDSVKKHIHSLLQTSSAFSFTTDIWTSSVSPVSLISLTSQWIDESFTPQRAILHVKQFRGSHTSQAIVHVFEEMLQTWGIPKTLVHVVLRDNAKNMIKAMNNAGLPSLPCVAHTLQLAVHEGLLAQRSIADAIAVGRKIVGHFKHSALAYSRLEDIQGQLNQPIKRLQQDVQTRWNSTYYMLQSLIEQKRVLGVYVSEHELPDCLTAHQWALMEKTVAILAPFEELTKKVSSYDALASDVIPAVTVLVRLLNRETDEDHGVKTMKATLLAAVKKRFSDVETNPLYFISTILDPRYKDRFFSN-NTAPEAKLHLKQELQMMSRAEAEGSRAEAAEPPAK--LFLKAQA---STSSSLDTVFEEIAKE---QPQAAQPLAAGAAIE--LDTYLGEAPSPREDSPLKYWGVNKIRFPTLAKMARKYLSAPCSSVESERLFSSVSHIIDENRNRLTADNAEKLLFLK 590          

Query:  583 MSKQLTSSIWNYFTVSPLINSKAICNLCNVSLSRGGNESKSFTTSNLVQHLRSKHVVAFADFXXXXXXXXXXXXXXXTASIPRPATIEALLDRRQPFEFNDKRALDWNKTIAEFMALDVQPFSVVDNVGFRRIIAKAEPRYTIPSSRYFSSTLIPAMHEKIQNKVREMVSSQPSTSLTSDAWSDPSISVALLSLTAHWVTE-DFQRKQAILAASPIEESHTGDYLGGMLLKILGDYTIEKSAVHVLLRDSGANMIKASRVADIDSISCFAHTLQLVINDSIMSQRSVKDILAISRSNVGKFRHSVLAQQHLSDLQGSLGVPKKKLVQDVQTRWNATLAMLRSLVEQKQVLGAYATE-HKLTNLDAHQWTLISHIIDTLSPFKDATKEVSDSQTSISVFLP----------KHTMSEGIMTMRQDILTSLNKRFAHTKENRKMVLATILDPRFKNFAYDDRELASTAKQWLKNECLILASAERSEEVVEPPSKRPRVETDQAHPGSSTSRLWDLFSDVVSEPALQTNSSIIGNVNDAVDAMIALYLSSAALP-RTENPYVWWNSNKLLFPYLATLSRRYLSAPASSVPSEQLFSGAWQIFSDRRGSLTAGKGEMLLLLKYNL 2406
            MSK+  S IW YFT S    S AIC  C   +SRGG   KSFTT+NLV HL+ KH   + +++   +++Q       +  + + AT+E    +   +  +D RA++    +AE +A+D QP S+VD++GF R++  AEPRYT+PS +Y + T+IP ++ ++  KV + +S     S TSD WS    + +L+SLTAHW++   F RK  +L AS I  SHT D +     ++L  + IE S +H  + D+ ANM KA        I CFAH++QLVI+D I+SQR V DILA  R  VG F+HS +A   L ++Q SL +P+++L QDV TRWN+TL ML+S++ QK VL AY TE   +  L +HQ  +I  II  L P  D TK +S  + S+S+ +P          K     G+ TM++++L SLN+RF   + N  +V+AT+LDP FK+  +        AK+ L  +    +  +  EE +EPP+K PR    Q             F +++ E + + +SS+          ++  YL+   +     N Y WW  NK  FP L+ L+ +YLS P +SV SE+LFS A  I+ ++R  L   + E LL +K N+
Sbjct:    1 MSKR-RSPIWQYFTASEGDKS-AICTTCGTQVSRGGKSVKSFTTTNLVNHLK-KHPAEYKEYEDAKRKEQLDATSTPSKPVLKQATLEESSTKMHKWAQSDSRAVNITTKVAEMIAVDCQPMSIVDDIGFTRVLHAAEPRYTLPSRKYMTDTVIPRVYSEVHMKVAKEISEAKWVSCTSDIWSTNISNESLISLTAHWLSPISFDRKSIMLNASHIPGSHTADAIRKKCKEMLQTWGIE-SRLHCFVVDNAANMKKAMADGKYIHIGCFAHSIQLVIHDGIISQRYVLDILAKCRRIVGHFKHSQVASSRLKEIQSSLCLPQQRLKQDVSTRWNSTLHMLQSIIAQKVVLAAYNTESDDIPQLSSHQLDIIDKIITVLKPVDDITKSISSEKASVSIIIPYIRALRKTWEKSGDDRGVQTMKKELLDSLNRRFCDIESNETLVVATLLDPCFKDKFFTSITEKEAAKELLITKITNNSHDQDIEESIEPPNKLPRTTVMQC------------FDEILEESSARLSSSL------CYTTIVEQYLAEPNIDYHAGNAYQWWAENKCRFPRLSELALQYLSPPPTSVASERLFSTAGDIYDEKRNRLDPERAETLLFIKNNI 599          

Query:  601 SSIWNYFTVSPLINSKAICNLCNVSLSRGGNESKSFTTSNLVQHLRSKHVVAFADFXXXXXXXXXXXXXXXTASIPRPATIEALLDRRQPFEFNDKRALDWNKTIAEFMALDVQPFSVVDNVGFRRIIAKAEPRYTIPSSRYFSSTLIPAMHEKIQNKVREMVSSQPSTSLTSDAWSDPSISVALLSLTAHWVTEDFQRKQAILAASPIEESHTGDYLGGMLLKILGDYTIEKSAVHVLLRDSGANMIKASRVADIDSISCFAHTLQLVINDSIMSQRSVKDILAISRSNVGKFRHSVLAQQHLSDLQGSLGVPKKKLVQDVQTRWNATLAMLRSLVEQKQVLGAYATEHKL-TNLDAHQWTLISHIIDTLSPFKDATKEVSDSQTSISVFLP-----KHTMS------EGIMTMRQDILTSLNKRFAHTKENRKMVLATILDPRFKNF------AYDDRE-------------LASTAK-QWLKNECLILASAERSEEVVEPPSKRPRVETDQAHPGSSTSRLWDLFSDVVSE------PALQTNSSIIGNVNDAVDAMIALYLSSAALPRTENPYVWWNSNKLLFPYLATLSRRYLSAPASSVPSEQLFSGAWQIFSDRRGSLTAGKGEMLLLLKYNLPQFSFNC 2427
            S++W YF +    +  A CNLC+ S+SRGG+    F T+N+++HL+  H   +A+F   SK KQ+        S+P   T+   + RR+ F     RA    + + EF+ LD QP SVV+N GFRR+I   EPRY +P+  + S   IP  +++++  + E +   P+ S+T+D WS     ++LLSLT HW+   F  ++A+L A     SHTG+ +   + ++L  + I K+ VHV+LRD+ +N+ KA     + S+ CFAHTLQLV+N+ +++QR V D + + R  VG F+HS  A   L D+Q  L +  K+L+QDV+TRWN+T  M+++L EQK+ L AY+ E+ L   L A QW L+  ++  L+PF++ TKEVS S +S S  +P     K  +S      +GI  M+  +L ++N+RF   +      +AT+LDPR+K+        Y +R              LA   K ++L+        AE +  V+EP  K PRVE+      SS SRL  +F +++ +      P L T S+ +          +  YLS   + R++NP ++W  NKL FP L + + ++L AP +S+ SE+LFS A  I  +RR  LTA K EML+ LK NLP     C
Sbjct:    2 SAVWTYFKLKDEKSKTAECNLCDASVSRGGSSVGIFNTTNMIKHLQKHHAKEYAEFSLASKAKQK--------SVPYQQTLLENIQRREKFPPESNRAKLITEKMVEFVVLDDQPLSVVENDGFRRLIEHLEPRYMLPNRHFISEEAIPGKYKQVRKFISESLEIIPTLSMTTDIWSSDVCPLSLLSLTVHWIDSSFTMQKAVLQAKEFCGSHTGESIAAAMEEMLNAWKIPKNKVHVVLRDNASNIKKAMSRLGVASLGCFAHTLQLVVNEGLLAQRGVCDAVTVGRKIVGHFKHSPQAYSRLEDIQMELNMSPKRLIQDVRTRWNSTYYMIKTLTEQKRALCAYSAEYDLPATLSAQQWGLLEKVLTALAPFEELTKEVSASSSSASDVIPIVCVLKRVLSRENEADDGIKKMKGTLLEAVNRRFRDVESEPLYTVATLLDPRYKDRYVRLHSCYFNRSTCFVCVCVCVNALLAEMRKMEFLRTTLNSSEPAEGTSAVLEPAKKTPRVES------SSQSRLESVFDEILKKNTQDPVPQLATTSARVE---------VQTYLSEPTIQRSDNPLLYWQVNKLRFPTLVSTAAKFLCAPTTSIESERLFSTASIIIDERRSRLTAEKVEMLIFLKKNLPLMLNEC 625          

Query:  583 MSKQLTSSIWNYFTVSPLINSKAICNLCNVSLSRGGNESKSFTTSNLVQHLRSKHVVAFADFXXXXXXXXXXXXXXXTASIPRPATIEALLDRRQPFEFNDKRALDWNKTIAEFMALDVQPFSVVDNVGFRRIIAKAEPRYTIPSSRYFSSTLIPAMHEKIQNKVREMVSSQPSTSLTSDAWSDPSISVALLSLTAHWVTEDFQRKQAILAASPIEESHTGDYLGGMLLKILGDYTIEKSAVHVLLRDSGANMIKASRVADIDSISCFAHTLQLVINDSIMSQRSVKDILAISRSNVGKFRHSVLAQQHLSDLQGSLGVPKKKLVQDVQTRWNATLAMLRSLVEQKQVLGAYATEHKL-TNLDAHQWTLISHIIDTLSPFKDATKEVSDSQTSISVFLPKHTM-----------SEGIMTMRQDILTSLNKRFAHTKENRKMVLATILDPRFKNFAYDDRELASTAKQWLKNECLIL----ASAERSEEVVEPPSKRPRVETDQAHPGSSTSRLWDLFSDVVSEPALQTNSSIIGNVNDAVDAMIALYLSSAALPRTENPYVWWNSNKLLFPYLATLSRRYLSAPASSVPSEQLFSGAWQIFSDRRGSLTAGKGEMLLLLKYNLP 2409
            M +   S++W YF ++    S A+CN+C  ++ RGG ++ +F T+NL++HL+  H    A F + +K K + +    TA+  +  T+   L RR+ F     +AL   + + EF+ LD QP S V++ GFRR++   EPRY++PS +YFS T +P +++K+   + + +    S S T+D WS     ++LLSLT HW+     R+ A+L A     SHT D +   + ++L  + I  + VH++LRD+ +N+ KA     + S+ CFAHTLQLV+N+ ++SQRSV D +AI R  VG F+HS LA   L D+Q  + +  K+L QDV+TRWN+T  +++SL+EQK+VLGAY  ++ L + L A+QW L+      L+PF++ T++VS +  S +  +P  T+             GI TM++ +L ++N+RF   ++     LAT+LDPR+K+  +   + A +AK  L  E   L    +S   + E  EP  K PRVE   A P  S S     F  +V E             + +    +  YL+   +  ++NPY +W  NK   P LA  + +YL AP +SV SE++FS  + I  ++R  LTA + EML+ ++ NLP
Sbjct:    1 MERAKESAVWRYFMLAAPTCSTAVCNVCKGNVLRGGGKTATFNTTNLIKHLQKHHAKEHAKFLQLNKTKGKGDN---TAATAQQLTLADALQRREKFPTESLKALGITQKVLEFIVLDAQPMSFVEDEGFRRLLEYLEPRYSLPSRKYFSETALPELYKKVCEHISKEIKDVKSMSFTTDIWSSAVCPMSLLSLTVHWLDVSCTRRGAMLQAKNFHGSHTSDTISAAIKEMLDQWHIPLNKVHLILRDNASNIKKAMDNMGVRSLGCFAHTLQLVVNEGLLSQRSVSDAIAIGRQIVGHFKHSPLAYSRLQDIQLQMQMQPKRLQQDVKTRWNSTY-LIQSLLEQKRVLGAYIADNDLPSTLTANQWALLEKTSIVLAPFEELTRKVSSATASTADVIPAVTVLKRILAKEGDADTGIKTMKKTLLEAVNRRFDSVEDEPLYALATLLDPRYKDRYFTSAQSAMSAKDALTGELEELEDLRSSTAGASEAAEPQEKAPRVEAAAAAP--SKSSFMQEFDQIVEE-----CEDPSAASSSSPAVQLHGYLAEKTIATSDNPYQYWGVNKYRLPCLAATATKYLCAPCTSVESERVFSTVFNIVDEKRNRLTAERTEMLVFMRKNLP 614          

Query:  601 SSIWNYFTVSPLINSKAICNLCNVSLSRGGNESKSFTTSNLVQHLRSKHVVAFADFXXXXXXXXXXXXXXXTASIPRPATIEALLDRRQPFEFNDKRALDWNKTIAEFMALDVQPFSVVDNVGFRRIIAKAEPRYTIPSSRYFSSTLIPAMHEKIQNKVREMVSSQPSTSLTSDAWSDPSISVALLSLTAHWVTEDFQRKQAILAASPIEESHTGDYLGGMLLKILGDYTIEKSAVHVLLRDSGANMIKASRVADIDSISCFAHTLQLVINDSIMSQRSVKDILAISRSNVGKFRHSVLAQQHLSDLQGSLGVPKKKLVQDVQTRWNATLAMLRSLVEQKQVLGAYATEHKL-TNLDAHQWTLISHIIDTLSPFKDATKEVSDSQTSISVFLP-----------KHTMSEGIMTMRQDILTSLNKRFAHTKENRKMVLATILDPRFKNFAYDDRELASTAKQWLKNECLILAS---AERSEEVVEPPSKRPRVETDQAHPGSSTSRLWDLFSDVVSEPALQTNSSIIGNVNDAVDAMIALYLSSAALPRTENPYVWWNSNKLLFPYLATLSRRYLSAPASSVPSEQLFSGAWQIFSDRRGSLTAGKGEMLLLLKYNL 2406
            S++WN+F +       A CN+C +S+SRGG +  +F T+NL++HL++KH   +++F   ++ K        T S P   T+EA+L  ++    +  +A +    IAEF+ALD QP SVV NVGFRR++   EPRY +PS  YF+ T +P++H K+++ +  M+S   +   T+D WS     ++L+S TA W+   F  ++A L A     SHT +++   + ++L  + IEK  VHV++RD+  NM +A     + S+ C AHTLQLV+++ ++SQRSV D +A +R  +G F+HS LA   L D+Q SL +  K+L QDV  RWN++L ML+S++EQK+ L  Y  +H L   L + QWTL+ +  + L P ++ T+EVS    + +  +P           + T  +G+ TM++ +L ++  RFA  ++     +AT++DPR+K+  +   +    AK  L  E + +     A +  E  EP SK PR          + S L  +  +++ E   +  S    NVN      +  YLS   +PR  NP  +W ++   FP LA ++ ++L AP +SV SE+LFS    I  + R  L+  K EML+ LK N+
Sbjct:    2 SAVWNHFKLETEGCPTATCNICKLSVSRGGKDRAAFNTTNLIRHLKNKHPAQYSEFTAATQIK--------TWSQP---TLEAMLKNKEKLPKDSDKAKNITAKIAEFIALDDQPLSVVSNVGFRRLMEHLEPRYELPSRSYFTDTALPSIHNKLRDHLLVMLSKVSAFGFTTDIWSSSVCPMSLISFTAQWIDSSFNLQRATLNAQHFRGSHTAEHVKQAIEEMLNSWGIEKERVHVIVRDNARNMKRAMEDLAVPSLGCVAHTLQLVVHEGLLSQRSVTDTMANARKIIGHFKHSPLAYSRLEDIQISLKMTVKRLQQDVHVRWNSSLYMLQSILEQKRALSIYTADHNLPATLTSSQWTLMENTAEVLVPLEELTREVSKETATAADVIPAISALRRVLSREQTTDQGVRTMKRTLLEAVETRFAEVEKETLYSIATLVDPRYKDRYFTKSDHLRFAKDSLIQEVMKMEENRVASKEPEAAEPVSKAPR--------QGAGSSLGSILDEILEERQPEAQSG--HNVN------LQGYLSEQTIPRKSNPLDYWKTHATQFPSLAAVATKFLCAPCTSVDSERLFSAVSNILDENRNRLSPDKLEMLIFLKKNM 591          

Query:  574 FEEMSKQLTSSIWNYFTVSPLINSKAICNLCNVSLSRGGNESKSFTTSNLVQHLRSKHVVAFADFXXXXXXXXXXXXXXXTASIPRPATIEALLDRRQPFEFNDKRALDWNKTIAEFMALDVQPFSVVDNVGFRRIIAKAEPRYTIPSSRYFSSTLIPAMHEKIQNKVREMVSSQPSTSLTSDAWSDPSISVALLSLTAHWVTEDFQRKQAILAASPIEESHTGDYLGGMLLKILGDYTIEKSAVHVLLRDSGANMIKASRVADIDSISCFAHTLQLVINDSIMSQRSVKDILAISRSNVGKFRHSVLAQQHLSDLQGSLGVPKKKLVQDVQTRWNATLAMLRSLVEQKQVLGAYATEHK--LTNLDAHQWTLISHIIDTLSPFKDATKEVSDS-QTSISVFLP-----KHTMS--------EGIMTMRQDILTSLNKRFAHTKENRKMVLATILDPRFKNFAYDDRELASTAKQWLKNEC--LILASAERSEEVVEPPSKRPRVETDQA--HPGSSTSRLWDLFSDVVSEPALQTNSSIIGNVNDAVDAMIAL--YLSSAALPRTENPYVWWNSNKLLFPYLATLSRRYLSAPASSVPSEQLFSGAWQIFSDRRGSLTAGKGEMLLLLKYN 2403
             E + K+  S +W +F + P  ++K  C +C+  L+   N      TS++++H R+K        +      Q          I  P++ + L                 +  +   +  D+QPF++VD+ GFR  +   +P Y IPS +   S ++ A + + + K +E V    + SLTSD W+   +  A L++T H + E  +    +L      +SH+ + L  +   ++ ++ I+K  V  L+ D+  NM+  + +  +    C AH L L++  +I     ++ I + +R   G FR S  A++ L  +QG +G P  KL+Q+V+TRWN+T AML+ + +Q++ +GA     K  LT L + ++  I+  +  LS F +AT E+S+  + S S  +P     +H ++        E  + +  ++   LN R +  +    M LAT+LDPR+K   +  +  A  A + L  EC  +I    +++       + +P++E   A      ST   ++    +++          +  +N   DA + +  YLS   +PRTE+P  +W S K ++P+L  L+  +L  PASSVP E++FS A ++ + +R  L     E +L L  N
Sbjct:    1 MEPVRKRGRSEVWEHFELLP--SNKVKCLVCSQQLAYNNN------TSSMLRHFRAKRENIPCQSRTTLSSTQGIAYSFLLVYIFYPSSQQML-----------------DSALVNMIVKDLQPFTIVDDAGFREFVGILDPTYVIPSRKALKS-MVEAKYTETKEKAKEEVQKATAVSLTSDMWTSIHMD-AYLAITCHLINEKDELSTFLLGVGKFPKSHSAENLAEVKTALMAEWGIQKK-VRCLVTDAAPNMVACAGLLKMLHTICIAHALNLIVKKAIDQTPGLEHIRSKARKIAGYFRSSTTAKERLFQMQGQMGRPTLKLIQEVETRWNSTFAMLQRMYQQREPVGAALVTLKTDLTPLTSEEYHTINECLGVLSTFNEATTELSEERRVSGSKVIPLIRMLRHALNTKQSQAQDEKSIQLCSNLFRLLNDRVSSYETMSIMTLATLLDPRYKTVGFCSQSNAQAAVKRLTGECATVIRTQEQQNTTSTSSATSQPQLEATVASSSTTPSTGTPYETLFLLIT----------VMKINATADATVEVQRYLSDPIIPRTEDPLRFWASQKNVYPHLYHLALEFLCTPASSVPCERIFSKAGEVVTKKRNQLNPSTVEKILFLNKN 594          

Query:  583 MSKQLTSSIWNYFTVSPLINSKAICNLCNVSLSRGGNESKSFTTSNLVQHLRSKHVVAFADFXXXXXXXXXXXXXXXTASIPRPATIEALLDRRQPFEFNDKRALDWNKTIAEFMALDVQPFSVVDNVGFRRIIAKAEPRYTIPSSRYFSSTLIPAMHEKIQNKVREMVSSQPS--TSLTSDAWSDPSISVALLSLTAHWVT---------EDFQRKQAILAASPIEESHTGDYLGGML-----LKILGDYTIEKSAVHV--LLRDSGA--NMIKASRVADIDSISCFAHTLQLVINDSIMSQRSVKDILAISRSNVGKFRHSVLAQQHLSDLQGSLGVPKKKLVQDVQTRWNATLAMLRSLVEQKQVLGAYATEHKLTNL-DAHQWTLISHIIDTLSPFKDATKEVSDSQTSISVFLPK-HTMSE----------GIMTMRQDILTSLNKRFAHTKENRKMVLATILDPRFKNFAYDDRELASTAKQWLKNECLILASAERSEEV-VEPPSKRPRVETDQAHPGSSTSRLWDLFSDVVSEPALQTNSSIIGNVNDAVDAMIALYLSSAALPRTENPYVWWNSNKLLFPYLATLSRRYLSAPASSVPSEQLF--SGAWQIFSDRRGSLTAGKGEMLLLLKYNLPQFSF 2421
            M  + TS +WN+F++S    +K +C  CN ++SRG  ++ +  TS L +H++  H     +    S +   A        +   A ++    + + FE     A    K IAE +ALD+QP +VV+NVG  R++   +P+Y++PSS YF+ST IP M+E ++  V   +    S     T+  W   S +   L+LTAHWVT         +DF    A+L  SPI+     DY   ML     L+ L D  I  S + +   + D+ A  N++K S  A    + CF H + L++N++I SQR V+++L+I+R    +   S  A++ L++LQ    +P+ +LVQDV ++W  +  ML  LVEQK+ +   + E     L    QW ++  + + L PF+ A +E+S   +++   +P  H ++           GI  M + +  ++  R +    + +   AT+LDPR+K   + + E A   KQ L  E   ++ A  S +   +  +    V      P      LW L  D + +   Q           + D ++  YL    L ++ +P  +WN  K  +P LA ++ RY+  P S VP+E LF  S A    S  R  L   +G  LL LK NLP   F
Sbjct:  646 MFSKKTSKLWNHFSISTGDPTKVVCLHCNRTISRG-KKTTNLGTSCLFRHMQRFHGHMLENSSSISGDVSSAALAVKQELMDTSAYVQ----QNKKFEDCHPVAKKITKLIAEMLALDLQPSTVVENVGLNRLLDYLQPQYSVPSSSYFTSTAIPEMYETVKEVVLTHLKEAESGIIHFTTSMWVS-SQTREYLTLTAHWVTFESRVRPQGQDFHC-SALLGVSPID----CDY--NMLSIQKQLEYLWDTWIASSGLKIGFTVTDNQAIGNVLKDSNHA---IMHCFGHNIDLIVNEAIKSQRMVQNLLSIARKICERVHRSAKAKERLAELQKEYNLPENQLVQDVPSKWKTSYFMLERLVEQKKAIDELSLECNFRELISCDQWEVMQSVCNALKPFEVACQEMSAHTSTLGQVIPLIHILNRKIDMLFDETMGIDNMLKSLKEAMVTRMSPILHDTRYTWATMLDPRYKTSLFTEEE-AEQCKQDLIRELDKVSLATTSPDTKTQLSNGCVEVPASSDGPSGKKENLWALM-DGIRQKIKQEERP------KSPDLIVVEYLEEEILDQSCDPLDYWNLKKFQWPELAKVAVRYVGCPPSIVPAETLFSTSSANCALSQSRPLLENLEG--LLFLKVNLPLVYF 1267          

Query:  574 FEEMSKQLTSSIWNYF--------TVSPLINSKAICNLC--NVSLSRGGNESKSFTTSNLVQHLRSKHVVAFADFXXXXXXXXXXXXXXXTASIPRPATIEALLDRRQPFEFNDKRALDWNKTIAEFMALDVQPFSVVDNVGFRRIIAKAEPRYTIPSSRYFSSTLIPAMHEKIQNKVREMVSSQPSTSLTSDAWSDPSISVALLSLTAHWVTEDFQRKQAILAASPIEESHTGDYLGGMLLKILGDYTIEKSAVHV-LLRDSGANMIKASRVADIDS-ISCFAHTLQLVINDSIMSQRSVKDILAISRSNVGKFRHSVLAQQHLSDLQGSLGVPKKKLVQDVQTRWNATLAMLRSLVEQKQVLGAYATE-------HKLTNLDAHQWTLISHIIDTLSPFKDATKEV-SDSQTSISVFLP-KHTM----------SEGIMTMRQDILTSLNKRFAHTKENRKMVLATILDPRFKNFAYDDRELASTAKQWLKNECLILASAERSEEVVE-----PPSKRPRVETDQAHPGSSTSRLWDLFSDVVSEPALQTNSSIIGNVNDAVDAMIALYLSSAALPRTENPYVWWNSNKLLFPYLATLSRRYLSAPASSVPSEQLFSGAWQIFSDRRGSLTAGKGEMLLLLKYNL 2406
             E     L S++W YF        +V  +  +  +C +C   V     GN      T+N+  H+R  H              ++ +    T+S+ +P    + + +         RA      I  F+A D+QP+SVV+N GF+ +I+  EPRY+IPS  + ++ ++P+M+E  +  V   +S+    ++T+D W+  +   + +++TAH+V  +++ +  +L   PI ESHT D L  +L + + ++ +++    + +  D+  N++ AS  A +   I CFAHT+ L      +    +  +L   R  V  F  S  A   L   Q  L +P  KL+QDV TRWN++  ML   +EQ+  + +  TE         L  L     T++  +++ L P K  T  + S+ Q ++S+ LP KH++          S+ +  ++  I T++  R+++    + +  +T LDPRFK+  + D     + K+   N    +     +++  +     PP       + +  P +  + L +LF D  S       +  +    D V   I LY  +  +    NP  WW +N+  +P L+ LS+ YL+  A+SV SE++FS A  I + +R +L+    ++L+ LK NL
Sbjct:   12 LEAAPASLKSAVWKYFAFPVSYVASVRVVDRNTTVCKMCYMRVPYPATGN------TTNMAAHIRRHH--------------KDVDLTGKTSSLVQPTIQSSFVVK---LAQTSARAEAITNAIGLFIAADLQPYSVVENTGFKHLISVLEPRYSIPSRSHLTTKVLPSMYEDTKENVLRGLSNAELIAITTDGWTSRATE-SYITVTAHYVNNEWEIESPVLQTRPIYESHTSDNLAEVLQEAVLEWKLDRQNTTIPVTTDNAKNIVNASNAAGLSPHIGCFAHTVNLASQKG-LGVNQISRLLGKVRRVVTFFHKSTTAAAVLKAKQEMLQLPPHKLIQDVATRWNSSYDMLTRYLEQQAAVYSALTEKDVKKNAKDLITLSDQDVTVLEDVVEVLKPMKTITTLLSSEQQPTVSMILPLKHSILTAMKHSGTDSQIVKDVKSAIATNIEGRYSNPSLQQFLNESTALDPRFKSLPHLDD---PSRKEIFNNLAEKIIQRHPTQDPGQGTSQNPPEDPETAASSEGSPPAKRTTLSELFGDFYSTAPTTPTTPELW--PDVVKEEIELYRMAKVISVDANPLKWWKNNEHQYPNLSKLSKHYLAVQATSVASERVFSTAGDIVTAQRAALSPDNVDILIFLKKNL 628          

Query:  589 KQLTSSIWNYFTV------SPLINSKAICNLCNVSLSRGGNESKSFTTSNLVQHLRSKHVVAFADFXXXXXXXXXXXXXXXTASIPRPATIEALLDRRQPFEFNDKRALDWNKTIAEFMALDVQPFSVVDNVGFRRIIAKAEPRYTIPSSRYFSSTLIPAMHEKIQNKVREMVSSQPSTSLTSDAWSDPSISVALLSLTAHWVTEDFQRKQAILAASPIEESHTGDYLGGMLLKILGDYTIEKSAVHVLLRDSGANMIKASRVADIDSISCFAHTLQLVINDSIMSQRSVKDILAISRSNVGKFRHSVLAQQHLSDLQGSLGVPKKKLVQDVQTRWNATLAMLRSLVEQKQVLGA-------YATEHKLTNLDAHQWTLISHIIDTLSPFKDATKEVSDSQT-SISVFLPKHTM-----------SEGIMTMRQDILTSLNKRFAHTKENRKMVLATILDPRFKNFAYDDRELASTAKQWLKNECLILASAERS---------EEVV----EPPSKRPRVETDQAHP---GSSTSRLWDLFS------DVVSE--PALQTNSSIIGNVNDAVDAMIALYLSSAALPRTENPYVWWNSNKLLFPYLATLSRRYLSAPASSVPSEQLFSGAWQIFSDRRGSLTAGKGEMLLLLKYNL 2406
            K L + +W +F          L  SKA+C LCN  L   GN      T+NL  HL   H                    Q TA  P    +E     + P   +  RA   ++ +  F+  D++P+SVV+NVGFR +I   EPRY +P+ ++ S   IP ++  +++ V   + S    +LT D+W   ++  + L++TAH++  +++    +L    IE SHT   L  +L + + ++ +       ++ D+ ANM +A  + ++  + CFAHTL L  + + +    V  +L   R     F  S  A   L + Q  LG+P  KLV DV TRWN+ L ML+  +EQ+  + A          E  L  L     T+   ++  L P K AT  +S+ ++ ++SV  P H             S  I  ++    T+L  R+   K+  K+ +A+ LDPRFK   +   E        L  E   L   E S         E +V    E  S  P   +D   P      +S L  L        D VSE  PA++                +  Y     +P +ENP  WW  +   +P LA  ++RYL  P +SVPSE++FS A  I + +R  LT    + LL L+ NL
Sbjct:   39 KNLKADVWLHFGFRSYGGREELDKSKAVCKLCNKELKYCGN------TTNLRNHLTRHH-----------------PDTQKTAE-PTQTPLEKAFAMKLPS--SSPRAKKISEALVTFICKDIRPYSVVENVGFRSLINVLEPRYVLPTRKHLSEVAIPNLYRDVKHGVATSLKSTERVALTCDSWVSRAMD-SYLTITAHYIDNEWRLMSHVLQTREIETSHTASNLAELLSEAIQEWELANKDP-AIVTDNAANMTRAVELTNLLHVGCFAHTLNLA-SQAALKTPPVARLLGRVRRIASFFHRSTTASHQLKEKQKILGLPAHKLVIDVTTRWNSALEMLQRFLEQQPAISAALLSPEVRRNESDLCTLSELDITVAEDVVKALGPLKAATLVMSEEKSPTLSVIAPLHAQLLAEMNNVTHDSTVIKDLKTAAHTNLKSRYVVLKD--KLYVASALDPRFKALPFLTDEARDNTFSKLVTEAAGLEPVEASIQQSDDDGAEHIVPVEQEDNSLDPVEVSDAPTPPKKPKESSALMSLLGPSYTPKDTVSEKTPAVKATEE------------VNRYREVKPIPLSENPLTWWRLHAGEYPLLARQAKRYLCIPGTSVPSERVFSTAGDIVTAQRSCLTPQHVDQLLFLQKNL 650          

Query:  907 KTIAEFMALDVQPFSVVDNVGFRRIIAKAEPRYTIPSSRYFSSTLIPAMHEKIQNKVREMVSSQPSTSLTSDAWSDPSISVALLSLTAHWVTEDFQRKQAILAASPIEESHTGDYLGGMLLKILGDYTIEKSAVHVLLRDSGANMIKASRVADIDSISCFAHTLQLVINDSIMSQRS-----VKDILAISRSNVGKFRHSVLAQQHLSDLQGSLGVPKKKLVQDVQTRWNATLAMLRSLVEQKQVLGAYATEHKLTNLDAHQWTL-------ISHIIDTLSPFKDATKEVS-DSQTSISVFLPKHTM--------SEGIMTMRQ---DILTSLNKRFAHTKENRKMVLATILDPRFKNFAYDDRELASTAKQWLKNECLILASAERSEEVVEP----------------------------PSKRPRVETDQAHPGSSTSRLWDLFSDVVSEPALQTNSSIIGNVNDAVDAMIALYLSSAALPRTENPYVWWNSNKLLFPYLATLSRRYLSAPASSVPSEQLFSGAWQIFSDRRGSLTAGKGEMLLLLKYNL 2406
            +++  F+  D++P SVV+N GFR+++   EPRYT+PS ++ +   +P ++++++ +V E +SS    +LT DAW+  +   + +++TA  +TE  +    +L    +  SHTG+ +  +L + + ++ +E +   V++ D+ +NM  A++ AD+  I CFAH+L L       SQ++     V+ +L+  R     FR S +A   L   Q  L +PK +L+ DV TRWN++  M+   +EQ+  + A     ++  ++   +TL          ++  L P KDAT  +S +S  ++++  P H          SE   T+++    I   L KR+   KE   + +A+ LDPRFK+  +     A T   + K    ++A+ E+    +E                             P KRPR        GS    L DL        A   +++   + +D   A I  +     LP TENP  WW  ++  +P L+ +++ +L  P +SV +E++FS A  I + +R  L A   + L+ L  NL
Sbjct:   65 QSVLYFICKDMRPLSVVENEGFRKMVNIMEPRYTLPSRQHITDIAVPRLYKEVKARVAEALSSTDRVALTCDAWTSRATE-SYVTITAPHITEKCELDTYVLQTRALHVSHTGENIADLLKEAVTEWRLE-AKDPVIVTDNASNMNIAAKRADMTHIRCFAHSLNLA------SQKAPKLPKVERLLSRIRLVTTFFRRSTIASHQLKQKQDLLQLPKHRLITDVVTRWNSSYDMIERFLEQQPEICAALLSTEVRKIEKDVFTLSETDITCAEEVLKALKPMKDATLVMSEESMPTLAIVAPLHAKLVMGTEESSEDTQTVKEIKTVIAQDLGKRYGSEKET--LFMASALDPRFKDLPFLSE--AETNDTYSKITAAVVAAIEKQHNQLEQIDSLVKETDQLKEVYHSADNVPALASQLPIKRPR--------GSCA--LLDLLGATF---ASTKDNAAQKSTHDVAAAEIKRFREETPLPLTENPLSWWKEHEHEYPQLSRVAKSFLCIPGTSVSAERVFSTAGNIVTAQRSVLKAEHVDQLVFLHKNL 591          

Query:  904 NKTIAEFMALDVQPFSVVDNVGFRRIIAKAEP----RYTIPSSRYFSSTLIPAMHEKIQNKVREMVSSQPSTSLTSDAWSDPSISVALLSLTAHWVTEDFQRKQAILAASPIEESHTGDYLGGMLLKILGDYTIEKSAVHVLLRDSGANMIKASRVADIDSISCFAHTLQLVINDSIMSQRSVKDILAISRSNVGKFRHSVLAQQHLSDLQGSLGVPKKKLVQDVQTRWNATLAMLRSLVEQKQVLGAYATEHK-LTNLDAHQWTLISHIIDTLSPFKDATKEVSDSQTSISV----------FLPKHTMSEGIMTMRQDILTSLNKRFAHTKENRKMVLATILDPRFKNFAYDDRELASTAKQWLKNECLILASAERS--EEVVEPPSKRPRVETDQAHPGSSTSRLWDLFSDVVSEPALQTNSSIIGNVNDAVDAMIALYLSSAALPR-TENPYVWWNSNKLLFPYLATLSRRYLSAPASSVPSEQLFSGAWQIFSDR 2349
            ++ I + + +++ P+SVV+   F+R+    +P    RY + S +Y+ +TL+PA ++K+   V  ++      S T+D WS+P+ S +LLS T H++ +   RK  IL+ + +E+ H G YL   L + +  + I +  +HV +RD+ ANM  A R+A +  I C +HTLQLV+ D++ +Q SV+ ++  +R  V   +HS  A +HL + Q ++  P+  L+QDV+TRWN    ML  LVEQ++ +  Y+ +   + +    +W L + ++  L PF  AT E+      ISV           L      +G+  M+  +  ++  RF+        + AT++DP FK+  Y + + A  AK+ + N    L S + S  + +  P +  P    D   PG  +S          SE   Q         +      +  YL    LPR T   Y +W+ ++  +P L   +++YLSAP  SV SEQLFS A Q+++DR
Sbjct:   26 DECIMDLIVVNMLPYSVVEGEAFKRL-KIGDPLGAHRYKVKSEKYYRTTLMPATYDKVVKHVTNLLQEATWISFTTDGWSNPTKSCSLLSFTGHFIHDAVWRK-VILSVTVLEQDHDGKYLASKLCEAMTKWEIAEK-IHVGVRDNAANMKLAMRLAGVADIGCMSHTLQLVLRDALFTQTSVEVVIKKARKIVTHLKHSEQACRHLVEHQQTVKTPEHSLLQDVETRWNGMYLMLERLVEQRKAVNLYSVQRSGIDSFSLAEWELAARVVKILKPFYTATLEICVDDACISVVILLVSNLNNMLNTTAADQGLKQMKATLRDAMCCRFSDISSLAPFLAATLIDPHFKD-TYFNVQKAVAAKKVVLN---FLRSVQESAMKNMTAPSAASP---IDNVEPGLESSE--------TSESGAQEEDDPWAAYDSQPANQLTNYLKELRLPRMTTGIYAYWHCSQ--YPLLEAAAQKYLSAPLISVASEQLFSAAGQLYADR 505          

Query:  601 SSIWNYFTVSPLINSKAI-CNLCNVSLSRGGNESKSFTTSNLVQHLRSKHVVAFADFXXXXXXXXXXXXXXXTASIPRPATIEALLDRRQPFEFNDKRALDWNKTIAEFMALDVQPFSVVDNVGFRRIIAKAEPRYTIPSSRYFSSTLIPAMHEKIQNKVREMVSSQPSTSLTSDAWSDPSISVALLSLTAHWVTEDFQRKQAILAASPIEESHTGDYLGGMLLKILGDYTIEKSAVHVLLRDSGANMIKASRVAD----IDSISCFAHTLQLVINDSIMSQRSVKD-ILAISRSNVGKFRHSVLAQQHLSDLQGSLGVPKKKLVQDVQTRWNATLAMLRSLVEQK----QVLGAYAT-----EHKLTNLDAHQWTLISHIIDTLSPFKDAT----KEVSDSQTSISVFLPK--------HTMSEGIMTMRQDILTSLNKRFAHTKENR----------KMVLATILDPRFKNFAYDDRELASTAKQWLKNECLIL----ASAERSEEVVEPPSKRPRVETDQAHPGSSTSRLWDLFSDVVSEPALQTNSSIIG--NVNDAVDAMIALYLSSAALPRTENPYVWWNSNKLLFPYLATLSRRYLSAPASSVPSEQLFSGAWQIFSDRRGSLTAGKGEMLLLLKYNL 2406
            S  W+YFT+  +   K + C  C ++L+      KS T  N  +HL  KH                   K+   +IP+       + RR+  +    RA      + + +  D++P  +V+ V FR  ++  EP Y++PS  YF   L    +E  Q  + E+  +    SL+ D W+  ++  A +S++ H++ ED+Q +  +L ++ + ESHT   +   +   L  + +E + +  ++ D+G NM  A+R+ +       + C AH+LQL++ D  +S+    D  + ++R  V  FR S  A   LS  +    + +  LV D  +RWN T  M+  L+E +     VLG  A         +  +   QW ++  +   L PF  AT     E   S +++ V +          H   +G+  +    +  L +R     E R           ++ A  LDPRF+   +     A   +  +  + +       SA R   VV+P               S   +L+  FSD   +       +++G  ++   V      Y +    PR  NP VWW  N+   PYL+ ++++ L  PA+S P++++FS A   F     SL      M++ L  N+
Sbjct:   18 SKCWDYFTM--MEGRKQVQCKTCLLTLTY----HKSTTMMN--KHLNRKHPNMLPLEDGHRDTTDVRIKKEIKLTIPK-------VRRRRCAQ---DRARSITGLLLQVIVKDLRPLDLVNGVAFREFLSFLEPGYSVPSVVYFEKMLEEKYNEVKQQCIAELKKAS-GLSLSCDVWNSAAVD-AYMSVSVHFIDEDWQLRNFLLESTNVLESHTPIVIRQWIEDALQRFEVEPAKIVSMVHDTGENMSAAARLLEEAYSWKPVQCAAHSLQLIVKDHGISKLPALDRAVDVARQLVEYFRKSEFALSQLSVREKEYNIIECPLVVDTPSRWNTTFDMIDRLLELRVPIAAVLGDMAVMPSWPSAPMELVMPQQWDMLMELKTLLEPFVHATAFLGSETHVSASTVPVLVKGLIRALEAVHYTLDGVEVVDSPHIQQLKERVKWQLEERWKFPTAPHVDFLLYAAALDPRFRGLKFLSGPDADAVRSHVLAKAIDFNRQDPSANRDPSVVKPTIIH----------VSGLDQLFAGFSDFADD----MEVAVVGSSDIEAIVYKEAEQYFNEKQTPRGVNPLVWWRDNQSRLPYLSRVAKQVLCLPATSSPADKIFSTAGLDFMRLCTSLHPSHLNMVIYLNRNM 628          

Query:  904 NKTIAEFMALDVQPFSVVDNVGFRRIIAKAEP----RYTIPSSRYFSSTLIPAMHEKIQNKVREMVSSQPSTSLTSDAWSDPSISVALLSLTAHWVTEDFQRKQAILAASPIEESHTGDYLGGMLLKILGDYTIEKSAVHVLLRDSGANMIKASRVADIDSISCFAHTLQLVINDSIMSQRSVKDILAISRSNVGKFRHSVLAQQHLSDLQGSLGVPKKKLVQDVQTRWNATLAMLRSLVEQKQVLGAYATE 1647
            +K I + + +++ P+SVV+   F+R+    +P    RY + S +Y+ +TL+PA H+K+   V  ++      S  +D     +I  +LLS T H + +   RK  IL+ + +++ H G++    + +           ++V +RD+ ANM  A R+A I  I C +HTLQLV+ D++ +Q SV+ ++  +R  V  F+HS  A +HL + Q ++  P+  L+QDV TRWN+   ML  LVEQ++ +  Y+ +
Sbjct:   84 DKCIMDLIVVNMLPYSVVEGEAFKRL-KIGDPLGAHRYKVKSEKYYRTTLMPA-HDKVVKHVTNLLQEATCISFITDG----AIH-SLLSFTGHIIHDAVWRK-VILSVTVLKQEHDGNHTKWEIAE----------KINVRVRDNAANMKMAMRLAGITDIGCMSHTLQLVLRDALFTQTSVEAVVKKARKIVTHFKHSEQACRHLVEHQQTIKSPEHSLLQDVDTRWNSAYLMLERLVEQRKAVNLYSVQ 317          

Query:  443 WLTLEICREYMRGECLRDEFSCRYAHPAKNLETQSGRVICCYDYLK 580
            WL LE+CR++ RG C R E  CRYAHP K++    GRVI C+D++K
Sbjct:   16 WLMLEVCRDFQRGTCSRTEDECRYAHPPKHVTAPHGRVIACFDFVK 61          

Query:  452 LEICREYMRGECLRDEFSCRYAHPAKN--LETQSGRVICCYDYLK 580
            LE+CRE+ RG C R E  CR+AHPA++  +++    V  C D++K
Sbjct:  139 LEVCREFQRGNCSRGESECRFAHPAESTAVDSADNTVTVCMDHVK 183          

Query:  443 WLTLEICREYMRGECLRDEFSCRYAHPAKNLETQSGRVICCYDYLK 580
            WL +E+CRE+ RG+C R E  CR+AHP  ++   +GRV  C+D LK
Sbjct:    7 WLQVEVCREFQRGKCSRTEDDCRFAHPPAHVAIHNGRVTACFDSLK 52          

Query:  452 LEICREYMRGECLRDEFSCRYAHPAKN--LETQSGRVICCYDYLK-KCR 589
            LE+CREY RG C R+E  CRYAHP ++  ++T  G V  C D++K KC+
Sbjct:  150 LEVCREYQRGACTREESECRYAHPPRHTSIDTSDGMVTVCMDFIKGKCQ 198          

Query:  598 TSSIWNYFTVSPLINSKAICNLCNVSLSRGGNESKSFTTSNLVQHLRSKHVVAFADFXXXXXXXXXXXXXXXTASIPRPATIEALLDRRQPFEFNDKR---ALDWNKTIAEFMALDVQPFSVVDNVGFRRIIAKAEPRYTIPSSRYFSSTLIPAMHEKIQNKVREMVSSQPS--TSLTSDAWSDPSISVALLSLTAHWVT---------EDFQRKQAILAASPIEESHTGDYLGGMLLKILGDYTIEKSAVHVLLRDSGANMIKASRVADIDSI-SCFAHTLQLVINDSIMSQRSVKDILAISRSNVGKFRHSVLAQQHLSDLQGSLGVPKKKLVQDVQTRWNATLAMLRSLVEQKQVLGAYATEHKLTN-LDAHQWTLISHIIDTLSPFKDATKEVSDSQTSISVFLPK-HTMSE----------GIMTMRQDILTSLNKRFAHTKENRKMVLATILDPRFKNFAYDDRELASTAKQWLKNECLILASAERSEEVVEPPSKRPRVETDQAHPGSSTSRLWDLFSDVVSEPALQTNSSIIGNVNDAVDAMIALYLSSAALPRTENPYVWWNSNKLLFPYLATLSRRYLSAPASSVPSEQLFSGAWQIFSDRRGSLTAGKGEMLLLLKYNLPQFSF 2421
            TS +WN+F++SP   +K +C  CN ++SRG        T+NL      +H+  F     ES      +A+ +   + +     ++ +  Q  E  D+    A    K +AE +ALD+QP +VV+N G  R++   +P+Y++P S YF+ST IP M+EK+++ V   +          T+  W   S +   L+LTAHW T         +DF    A+L+ S I+       +   L + L D  I  S +      +    I+ +       I  CF HT+ L+++++I SQR V+++L+I+R    +   S  A++ L +LQ +  +P+ +LVQDV ++W  +  ML  LVEQK  +   + E      +   QW ++  + + L PF+ A +E+S+   ++   +P  H +S           GI  M + +  +L  R + T  +++   AT+LDPR+K   + + E A   KQ L  E L  +S+  +E    PP+         +   S+   LW L  D+      +           + +  +  YL    L ++ +P  +WN  K L+P LA ++ RY+  P S VP+E LFS A    +  +        E LL LK NLP   F
Sbjct:  633 TSKLWNHFSISPADPTKVVCLHCNRTISRGKK------TTNLGTSCLFRHMQRFHGHVLESNNAISGDAQDAEIHVKQEVMETSVYETEQNCERFDEEHPVAKKITKLVAEMLALDLQPSAVVENAGLNRLLEYLKPQYSLPPSSYFTSTAIPDMYEKVKDVVLTHLKEAEGGVVHFTTSIWVS-SQTREYLTLTAHWATYESSVRPQGQDFH-CSALLSVSQIDCDQDMHDIPKQL-EYLWDSWITSSGLKRGFTLTDNITIQHTLEEHGHPIMECFGHTIDLIVSEAIKSQRMVQNLLSIARKICERVHRSAKAKEKLVELQRAHQLPENQLVQDVPSKWRTSFFMLERLVEQKNAIDEMSIECNFREIISCDQWEVMLSVCNALKPFEVACREMSNHTATLGQVIPLIHILSRKIDLLFDETVGIDNMLRSLKEALVSRMSATLHDQRYTWATMLDPRYKTSLFTEEE-AEQCKQDLIRE-LDSSSSTSAEAKSLPPNGCSDDPASHSSSHSNVDDLWSLMPDIRQRTKNEEKPK-------SSEEAVLEYLEEDILDQSCDPLDYWNLKKFLWPDLAKVAARYVGCPPSIVPAETLFSTASVNCALNQPRPMLDNIEGLLFLKVNLPLIYF 1249          

Query:  898 DWNKTIAEFMALDVQPFSVVDNVGFRRIIAKAEPRYTIPSSRYFSSTLIPAMHEKIQNKVREMVSSQPSTSLTSDAWSDPSISVALLSLTAHWVTEDFQRKQAILAASPIEESHTGDYLGGMLLKILGDYTIEKSAVHVLLRDSGANMIKASRVADIDSISCFAHTLQLVINDSIMSQRSVKDILAISRSNVGKFRHSVLAQQHLSDLQGSLGVPKKKLVQDVQTRWNATLAMLRSLVEQKQVLGAYATE--HKLTNLDAHQWTLISHIIDTLSPFKDATKEVSDSQTSI-SVFLPKHTM-----------SEGIMT--MRQDILTSLNKRFAHTKENRKMVLATILDPRFKNFAYDDRELASTAKQWLKNECLILASAERSEEVVEPPSKRPRVETDQAHPGSSTSRLWDLFSDVVSEPALQTNSSIIGNVNDAVDAMIAL--YLSSAALPRTENPYVWWNSNKLLFPYLATLSRRYLSAPASSVPSEQLFSGAWQIFSDRRGSLTAGKGEM 2382
            D ++ +   +  D QP S+V++ GFR  + K +P Y +PS +     ++   +++ +   +  +    + SLT D W+        L++  H+V E+ +    +L   P  ++H    +      ++ ++ +E   V  L+ D+   M+ A+    +  + C AH L  V+  ++     +K +   +   V  FR S  A++ L   Q  L +P  KLV++  +RW +T  ML+SL++ ++ +G+  T    K+  L   +    +  +  L PF  AT E+S+ +  + S+ +P   M           S+ +    + Q++   L + F   +EN  + LAT+LDPRFK   +  +E A  A Q L  EC  L         V P + RP  E   +        LW    D  S   ++T+S      N   DA + +  Y++   L R+++P V+W  +K ++P+L +L++++L  PASSVP E++FS A  +FS +R  L+    E+
Sbjct:   56 DLDQALVNLVVKDSQPCSIVEDRGFRDFVKKLDPSYALPSKQALKK-MVDDRYQEEKADAQAQLREAEAVSLTVDLWTSADTR---LAVACHYVLENSKLATVLLGVLPFPQNHGPTDVADAQRTLMAEWGLE-GKVKCLVSDTTPAMVAAADDLALPHVECIAHALNGVVRRALDKTAGLKGLRRRAGEVVALFRSSAAAKEKLRSKQQKLALPVTKLVREESSRWTSTFLMLQSLLDARRAVGSALTALGAKVEPLSCDESETSAACLQVLKPFYTATVEMSEQKRVLGSMGIPLVKMLLLATEEVAEESDNVTAELLGQNLSAGLRREFDGLEENPVLSLATLLDPRFKTIGFRCQEKAQQAVQTLTAECAAL---------VRPAADRP-TERPVSTFCPPAFNLWKSLDDQAS--MVRTHS------NATADATLEVQRYMTDPPLERSQDPLVYWKEHKNIYPHLFSLAKKHLCIPASSVPFERVFSKAGDVFSRKRNRLSPKAHEV 545          

Query:  589 KQLTSSIWNYFTVSPLINSKAICNLCNVSLSRGGNESKSFTTSNLVQHLRSKHVVAFADFXXXXXXXXXXXXXXXTASIPRPATIEALLDRRQPFEFNDKRALDWNKTIAEFMALDVQPFSVVDNVGFRRIIAKAEPRYTIPSSRYFSSTLIPAMHEKIQNKVREMVSSQPSTSLTSDAWSDPSISVALLSLTAHWVTEDFQRKQAILAASPIEESHTGDYLGGMLLKILGDYTIEKSAVHVLLRDSGANMIKASRV----ADIDSISCFAHTLQLVINDSIMSQRSVKDILAISRSNVGKFRHSVLAQQHLSDLQGSLGVPKKKLVQDVQTRWNATLAMLRSLVEQKQVLGAYATE--------HKLTNLDAHQWTLISHIIDTLSPFKDATKEVSDSQTSISVFLPK 1779
            +Q  S +W+++T++   N K  C  C + L+         +TS+++QHL  +H + +A     ++      +  S   + RPA    +           + A  + ++I   +  D++P S+V++ GFR +I+    +Y++PS  YF+  L+   H  I +K++ ++      +LT+D W+  +   A L +T H++ ED++ K   L   P+EE HT   +   L +    + I +  V  ++ D+ AN++ A+R+        S+ C  HTL LV+  ++ + +++   +  +R  V  F+ S LA   L + Q  +G P   L+QDV TRWN+T  ML  L+EQ+  + A  ++        H   +L   QW +   +   L PF+ AT+ +S  +      LP+
Sbjct:   10 RQKLSKVWDHYTLNKDEN-KVQCLYCKIELAYHN------STSSMIQHLNRRHPL-YAVSPSIAETSSSQRSMDSFVRLNRPAQSCTV-----------QEAAIFTESILNMLVTDMRPLSMVEDKGFRDMISTFNSKYSLPSRTYFTQ-LMEKKHRDITDKLKAVLKQTECVALTTDIWTSVATE-AYLGVTCHFLGEDWEMKSLSLTTMPLEERHTAANIADWLEETTAQFEIPREKVKAVVHDNRANVVAAARILTERHGWASVRCAGHTLNLVVQSTLKNNKTIASCVGSARCLVEHFKKSELACTKLKEKQQQMGKPLHMLIQDVSTRWNSTYHMLSRLLEQRWPVTAVLSDPAVNPRGKHHYLDLKPEQWHISEELTQILGPFEGATEFLSGEKYVTLSALPQ 397          

Query: 2206 ENPYVWWNSNKLLFPYLATLSRRYLSAPASSVPSEQLFSGAWQIFSDRRGSLTAGKGEMLLLLKYN 2403
            ENP  WW  N+  +P LA L++ +L  PA+S PSE+LFS A  I S RR SL+A   +ML  L  N
Sbjct:  455 ENPLPWWRINEARYPTLAQLAKSFLGIPATSTPSERLFSAAGNIASKRRASLSAQHVDMLTFLHCN 520          

Query:  601 SSIWNYFTVS------PLINSKAICNLC--NVSLSRGGNESKSFTTSNLVQHLRSKHVVAFADFXXXXXXXXXXXXXXXTASIPRPATIEALLDRRQPFEFNDKRALDWNKTIAEFMALDVQPFSVVDNVGFRRIIAKAEPRYTIPSSRYFSSTLIPAMHEKIQNKVREMVSSQPSTSLTSDAWSDPSISVALLSLTAHWVTEDFQRKQAILAASPIEESHTGDYLGGMLLKILGDYTIEKSAVHVLLRDSGANMIKASRVADIDSISCFAHTLQLVINDSIMSQRS-VKDILAISRSNVGKFRHSVLAQQHLSDLQGSLGVPKKKLVQDVQTRWNATLAMLRSLVEQKQVLGAYATEHKLTNLDAHQWTLISHIIDTLSPFKDATKEVSDSQTSIS--------------------VFLPKHTMSEGIMTMRQDILTSLNKRFAHTKENRKMVLATILDPRFKNFAYDDRELASTAKQWLKNECLILASAERSEEVVEPPSKRPRVETDQAHPGSSTSRLWDLFSDVVSEPALQTNSSIIGNVNDAVDAMIALYLSSAALPRTENPYVWWNSNKLLFPYLATLSRRYLSAPASSVPSEQLFSGAWQIFSDRRGSLTAGKGEMLLLLKYNL 2406
            S IW +F         P+   KAIC +C   VS+SRG        T+NL  HLR  H VAFA   + S           T+   R   +     R   ++    R      ++  ++  ++ PF  V+   F+ ++ + + +Y +P  +YFS T IP  +  +++ V + +      S+T+D WS  + ++  +SLT H+++ +++ K   L      ESHT D L   L     ++++++  +  +  D+GAN++ A R      ++CF H L L + +S+ +++      + + R+ V  F  S   ++ L   Q    +P+  LV  V   W     M+  ++EQ   +     + + +      W      I+ L     A K+V+D   ++S                    + LP +  +E    ++Q ++  L  +++     + +  A+ +DPR K         A T  Q    + L+       EE++  P +R  +   +A   ++ +      S   S P  +  + ++G         + + + +                   FP L+ ++R+YL+  A+S PSE++FS A  I +  R SL   K  ML+ L  N+
Sbjct:   31 SDIWAHFGFEADDKGQPVNLDKAICRICRTEVSVSRGN-------TTNLRSHLRINHPVAFAGLGRTSSRPS-------TSGQQRQLGVSEAFARGAKYQSGSNRWRALTDSVTRYLVEEMVPFRTVEKPAFKAMLHEFDKQYVLPDRKYFSQTAIPEKYLSVKDGVIQELKYVDYFSVTADMWSSVN-NMPYMSLTIHYLSANWELKSKCLETVFTPESHTADNLAEALRSSFEEWSLDERKLICITTDNGANIVAAVRKLGWTWLNCFGHNLHLAVTNSMKTEKDRTARAMGVCRNLVTAFSQSWQKKKKLQKEQVEHNLPQHGLVL-VSCAWGTKQKMVARILEQIPAIRRVLMDDRRSQHLIPTW----QDIEVLESINAALKKVADFTDALSSEKTVTASSVLPVLQLLTEDILLPTNEDTELTRNIKQKMIEVLKDKYSAPGSQQLLAKASFIDPRHK---------ADTNSQHDTKDALL-------EEMLAMPEERRHIGGGEAAMSAAAAGEGKGESASSSPPKKKKLADLLGKRRAQSSNPVPIRICAR------------------FPLLSKVARKYLTVCATSTPSERVFSAAGNIVTPLRSSLKPDKVNMLVFLSRNM 607          

Query:  640 NSKAICNLCNVSLSRGGNESKSF----TTSNLVQHLRSKHVVAFADFXXXXXXXXXXXXXXXTASIPRPATIEALLDRRQPFEFNDKRALDWNKTIAEFMALDVQPFSVVDNVGFRRI--IAKAEPRYTIPSSRYFSSTLIPAMHEKIQNKVREMVSSQPSTSLTSDAWSDPSISVALLSLTAHWVTEDFQRKQAILAASPIEESHTGDYLGGMLLKILGDYTIEKSAVHVLLRDSGANMIKASRVADIDSISCFAHTLQLVINDSIMSQRSVKDILAISRSNVGKFRHSVLAQQHLSDLQGSLGVPKKKLVQDVQTRWNATLAMLRSLVEQKQVLGAY--ATEHKLTNLDAHQWTLISHIIDTLSPFKDATKEVS-DSQTSISVFLPKHTMSEGIMTMRQD-------ILTSLNKRFAHTKE---NRKMVLATILDPRFKNFAY---DDRELASTAKQWLKNECLILASAERSEEVVEPPSKRPRVETDQAHPGSSTSRLWDLFSDVVSEPALQTNSSIIGNVNDAVDAMIALYLSSAALPRTENPYVWWNSNKLLFPYLATLSRRYLSAPASSVPSEQLFSGAWQIFSDRRGSLTAGKGEMLLLLKYNLPQ 2412
              K IC +CN          K F    + S+L  H+ +KH  AFA                 +AS  R  T    L+ R+P   +    L    TIA+++A D +P S+V++ GF  +  +A  +  Y  P SR    T I A++E  + K +E+++     +LT D  +  S +   L +TAH++++ ++ K   L     EE H  +   G  L +   + IE      +  +S  NM+ A R+   + ++C AH          M QR V   LA S                      SLG  ++ L+QDV TRWN+ L M++ +   K+ + A     EHKL    A +W  +  +   L P +  T+ +  ++  S SV LP        M    +         T   +  A  +E   N  + +AT+LDPRFK+       DRE   T                  E +++  S R   +T    P      L  + SD  SE              D V   I  Y +   +   E P  WW S+      LATL+ +YL+ PA++VP E+LFS A  I   ++ S T  K E     K +LPQ
Sbjct:   25 KCKVICKICN----------KEFQFHRSCSSLRYHVNAKH--AFAG-------------PSGSASGLRQTT----LNVRRPLTKSTSDHL--TNTIAKWIAKDCRPISIVEDSGFLDVLQVASQDSSYK-PPSRATVMTKIHALYESEKEKRKEVLAQVNYIALTGDHMTSVS-NDNYLGVTAHFISDTWELKSFALTILKTEERHFVEACKGQFLSVARKWDIEGKTT-TIGTESARNMVAAIRLTRYEHMNCVAH----------MVQRCVTVSLADS---------------------VSLGKKQEPLIQDVPTRWNSALEMVKRVSRNKEAVIAALDNQEHKLILPTAAEWDKLQRLETLLEPCRYVTELLGGEAYVSCSVVLPSLCHLRLKMEACDENPAYVVRFKTKFKEDLASRQEQLNNAWLQIATVLDPRFKDLKCLPKTDREAVWTT----------------LEGMLQQESPRKSSQTHDDGPPRKKISLLQMGSDSESE-------------EDEVQPAIQRYRAEPTIKLEECPLRWWASHSGAHEKLATLAHKYLATPATTVPCERLFSVAGHIVIKKKVSFTFRKCE-----KVSLPQ 538          

Query:  580 EMSKQLTSSIWNYFTVSPLINSKAICNLCNVSLSRGGNESKSFTTSNLVQHLRSKHVVAFADFXXXXXXXXXXXXXXXTASIPRPATIEALLDRRQPFEFNDKRALDWNKTIAEFMALDVQPFSVVDNVGFRRIIAKAEPRYTIPSSRYFSSTLIPAMHEKIQNKVREMVSSQPSTSLTSDAWSDPSISVALLSLTAHWVTEDFQRKQAILAASPIEESHTGDYLGGMLLKILGDYTIEKSAVHVLLRDSGANMIKASRVADIDSISCFAHTLQLVINDSIMSQRSVKDILAISRSNVGKFRHSVLAQQHLSDLQGSLGVPKKKLVQDVQTRWNATLAMLRSLVEQKQVLGAYATEHKLTNLDAHQWTLISHIIDTLSPFKDATKEVSDSQTSISVFLP-----------KHTMSEGIMTMRQDILTSLNKRFAHTKENRKMVLATILDPRFKNFAYDDRELASTAKQWLKNECLILASAERSEEVVEPPSKRPRVETDQAHPGSSTSRLWDLFSDVVSEPALQTNSSIIGNVNDAVDAMIALYLSSAALPRTENP 2214
            +MSKQLTSSIWNYFT SPLINSKAICNLCNVSLSRGGNESKSFTTSNLVQHLRSKHVVAF+DFQKESKEKQEAEAKQSTASIPRPATIEALLDRRQPFEFNDKRA DWNKTIAEFMALDVQPFSVVD+VGFRRIIAKAEPRYTIPSSRYFSSTLIPAMHEKIQNKVREMVSSQPS S TSDAWSDPSISVALLSLTAHWVTEDFQRKQAILAASPIEESHTGDYLGGMLLKILGDYTIEKSAVHVLLRDSGANMIKASRVADIDSISCFAHTLQLVINDSIMSQRSVKDILAISRS VGKFRHSVLAQQHLSDLQ SLGVPKKKLVQDVQTRWNATLAMLRSLV++KQVLGAYATEHKLTNLDAHQWTLISHIIDTLSPF+DATKEVSDSQTSIS+ LP           KHTMSEGIMTMRQD+LTSLNKRFAHT ENRKMVLATILDPRFKNFAYDD ELASTAKQWLKNECLILASAERSEEVVEPPSKRPRVETDQ HPGSSTSRLWDLFSDVVSEPALQTNSSIIGNVNDAVDAMIALYLSSAALPRTENP
Sbjct:   40 KMSKQLTSSIWNYFTDSPLINSKAICNLCNVSLSRGGNESKSFTTSNLVQHLRSKHVVAFSDFQKESKEKQEAEAKQSTASIPRPATIEALLDRRQPFEFNDKRAFDWNKTIAEFMALDVQPFSVVDSVGFRRIIAKAEPRYTIPSSRYFSSTLIPAMHEKIQNKVREMVSSQPSVSFTSDAWSDPSISVALLSLTAHWVTEDFQRKQAILAASPIEESHTGDYLGGMLLKILGDYTIEKSAVHVLLRDSGANMIKASRVADIDSISCFAHTLQLVINDSIMSQRSVKDILAISRSIVGKFRHSVLAQQHLSDLQTSLGVPKKKLVQDVQTRWNATLAMLRSLVDRKQVLGAYATEHKLTNLDAHQWTLISHIIDTLSPFEDATKEVSDSQTSISLVLPMLSMLRRLLDRKHTMSEGIMTMRQDMLTSLNKRFAHTTENRKMVLATILDPRFKNFAYDDGELASTAKQWLKNECLILASAERSEEVVEPPSKRPRVETDQTHPGSSTSRLWDLFSDVVSEPALQTNSSIIGNVNDAVDAMIALYLSSAALPRTENP 595          

Query:  583 MSKQLTSSIWNYFTVSPLINSKAICNLCNVSLSRGGNESKSFTTSNLVQHLRSKHVVAFADFXXXXXXXXXXXXXXXTASIPRPATIEALLDRRQPFEFNDKRALDWNKTIAEFMALDVQPFSVVDNVGFRRIIAKAEPRYTIPSSRYFSSTLIPAMHEKIQNKVREMVSSQPSTSLTSDAWSDPSISVALLSLTAHWVTEDFQRKQAILAASPIEESHTGDYLGGMLLKILGDYTIEKSAVHVLLRDSGANMIKASRVADIDSISCFAHTLQLVINDSIMSQRSVKDILAISRSNVGKFRHSVLAQQHLSDLQGSLGVPKKKLVQDVQTRWNATLAMLRSLVEQKQVLGAYATEHKLTNLDAHQWTLISHIIDTLSPFKDATKEVSDSQTSISVFLP-----------KHTMSEGIMTMRQDILTSLNKRFAHTKENRKMVLATILDPRFKNFAYDDRELASTAKQWLKNECLILASAERSEEVVEPPSKRPRVETDQAHPGSSTSRLWDLFSDVVSEPALQTNSSIIGNVNDAVDAMIALYLSSAALPRTENPYVWWNSN----KLLFPYLATLSRR 2274
            MSKQLTSSIWNYFTVSPLINSKAICNLCNVSLS+GGNESKSFTTSNLVQHLRSKHVVAFADFQKESKEKQEAEAKQSTASIPR ATIEALLD RQPFEFNDKRALDWNK IAEFMALDVQPFSVVDNVGFRRIIAKAEPRYTIPSSRYFSSTLIP MHEKIQNKVREMVSSQPS S TSDAWSDPSISVA LSLTAHW                  ESHTGDYLGGMLLKILGDYTIEKSAVHVLLRDSGANMIK SRV DI SISCFAHTLQLVINDSIMSQRSVK+ILAISRS VGKFRHSVLAQQ+LSDLQGSLGVPKKKLVQDVQTRWNATLAMLRSLVEQKQVLGAYATEH+L NLDAHQWTLISHIIDTLSPF+DATK+VSDSQTSISV LP           KHTMS+GIMTMRQD+LTSLNKRFAHTKENRKM                   LASTA QWL NECLILASAERSEEVVEP SKRPRVETD AHPGSSTSRLWDLFSDVVSEPALQTNSSIIGNVNDAVDAMI +YLSSAALPRTENPY+   +N      LFP +    +R
Sbjct:    1 MSKQLTSSIWNYFTVSPLINSKAICNLCNVSLSQGGNESKSFTTSNLVQHLRSKHVVAFADFQKESKEKQEAEAKQSTASIPRHATIEALLDSRQPFEFNDKRALDWNKIIAEFMALDVQPFSVVDNVGFRRIIAKAEPRYTIPSSRYFSSTLIPVMHEKIQNKVREMVSSQPSVSFTSDAWSDPSISVAFLSLTAHW------------------ESHTGDYLGGMLLKILGDYTIEKSAVHVLLRDSGANMIKESRVVDIHSISCFAHTLQLVINDSIMSQRSVKNILAISRSIVGKFRHSVLAQQYLSDLQGSLGVPKKKLVQDVQTRWNATLAMLRSLVEQKQVLGAYATEHELKNLDAHQWTLISHIIDTLSPFEDATKKVSDSQTSISVVLPMLSMLRRLLDRKHTMSKGIMTMRQDMLTSLNKRFAHTKENRKM-------------------LASTANQWLNNECLILASAERSEEVVEPSSKRPRVETDPAHPGSSTSRLWDLFSDVVSEPALQTNSSIIGNVNDAVDAMIPVYLSSAALPRTENPYMTSPNNIPRIPRLFPSIVATRQR 542          

Query:  290 MIPFNSSSVLLNIAQTXXXXXXXXXXXXXINFNSIPVXXXXXXXXXXXXXEWLTLEICREYMRGECLRDEFSCRYAHPAKNLETQSGRVICCYDYLK-KCR 589
            MIPFNSSSVLLNIAQTNSSSSACNSKRNSINFNSIPVKPKSNSFSSSKDSEWLTLEICREYMRGECLRDEFSCRYAHPAKNLETQSGRVICCYDYLK KC 
Sbjct:    1 MIPFNSSSVLLNIAQTNSSSSACNSKRNSINFNSIPVKPKSNSFSSSKDSEWLTLEICREYMRGECLRDEFSCRYAHPAKNLETQSGRVICCYDYLKGKCH 101          

Query: 1225 IEESHTGDYLGGMLLKILGDYTIEKSAVHVLLRDSGANMIKASRVADIDSISCFAHTLQLVINDSIMS--QRSVKDILAISRSNVGKFRHSVLAQQHLSDLQGSL 1533
            ++ SH+G  +G  L +IL ++ I      +++ D+GA+M  A+R+     + C+ HT+QLV+ND + S  Q SV D +A++RS  G  RHS  A + L  +Q SL
Sbjct:    1 MQGSHSGQLIGSHLQEILREWNINDDRKGIIVSDNGASMKAAARLGGFQYLGCYIHTIQLVVNDELKSSTQSSVADTIAVARSIAGHLRHSTQATEALRKIQVSL 105          

Query:  440 EWLTLEICREYMRGECLRDEFSCRYAHPAKNLETQSGRVICCYDYLK-KC 586
            +WLTLE+CRE+ R  C R+E  C+YAHP   +ETQ+GRV+CCYD +K KC
Sbjct:   38 QWLTLEVCREFQRSMCPRNELECKYAHPPPYIETQNGRVMCCYDSIKGKC 87