Neur_chan_LBD domain-containing protein

Overview
NameNeur_chan_LBD domain-containing protein
Smed IDSMED30028543
Length (bp)1376
Neoblast Clusters

Zeng et. al., 2018




▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 



 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)




Explore this single cell expression dataset with our NB Cluster Shiny App




 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Neur_chan_LBD domain-containing protein (SMED30028543) t-SNE clustered cells

Violin plots show distribution of expression levels for Neur_chan_LBD domain-containing protein (SMED30028543) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Neur_chan_LBD domain-containing protein (SMED30028543) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Neur_chan_LBD domain-containing protein (SMED30028543) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017




Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020




SMED30028543

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 9

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
head regionSMED30028543h1SMcG0003944 SmedASXL_013393SmedAsxl_ww_GCZZ01PMID:27034770
Currie et al., 2016
whole organism asexual adult RNA-sequencing evidence
nervous systemSMED30028543h1SMcG0003944 dd_Smed_v4_23073_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30028543h1SMcG0003944 dd_Smed_v4_23073_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymaSMED30028543h1SMcG0003944 dd_Smed_v4_23073_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
neuronSMED30028543h1SMcG0003944 Contig16482newmark_estsPMID:27612384
Roberts-Galbraith et al., 2016
whole organism asexual adult colorimetric in situ hybridization evidence
neuronSMED30028543h1SMcG0003944 Contig16482uc_Smed_v2PMID:27612384
Roberts-Galbraith et al., 2016
whole organism asexual adult colorimetric in situ hybridization evidence
lateral branchSMED30028543h1SMcG0003944 Contig16482newmark_estsPMID:27612384
Roberts-Galbraith et al., 2016
whole organism asexual adult colorimetric in situ hybridization evidence
lateral branchSMED30028543h1SMcG0003944 Contig16482uc_Smed_v2PMID:27612384
Roberts-Galbraith et al., 2016
whole organism asexual adult colorimetric in situ hybridization evidence
head regionSMED30028543h1SMcG0003944 OX_Smed_1.0.12345ox_Smed_v2PMID:24238224
Kao et al., 2013
whole organism asexual adult RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
BLAST of Neur_chan_LBD domain-containing protein vs. Ensembl Human
Match: GABRB3 (gamma-aminobutyric acid type A receptor beta3 subunit [Source:HGNC Symbol;Acc:HGNC:4083])

HSP 1 Score: 52.373 bits (124), Expect = 1.092e-6
Identity = 58/257 (22.57%), Postives = 110/257 (42.80%), Query Frame = 3
Query:  261 VCVVF-LKIGEIDTIKE---QYAADILIKCKWREPRLDHNTEKLEYDWANSWTPKLYIENT--IGEAKEHVYQMIIFNE----NQHAFLCEKRRVSGIFLENLELNHFPFDVQDLTITIASNLPSTEIRLVNDPDETHRVNKQSFVDEQEWYLFKHIETEQKELAYEYADPSSVKPAISVKCRAARRPAYFIWNIFLVTFLICSLSLVTFAVDKSLPQNRLQXXXXXXXXXXXXXXXXNQCLPKISYLTYLDKYVIS 1001
            VCV   + I  ID + E    Y   +  +  WR+ RL ++   L     N    +L++ +T  + + K  V+ + + N     +    +    R++      ++L  +P D Q+ T+ I S   +T+     D +   R   ++    +   L +    E + ++      +   P +S+  R  R   YFI   ++ + LI  LS V+F ++      R+ L  T VLT+      + + LPKI Y+  +D Y++ 
Sbjct:   61 VCVGMNIDIASIDMVSEVNMDYTLTMYFQQYWRDKRLAYSGIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTD-----DIEFYWRGGDKAVTGVERIELPQFSIVEHRLVSRNVVFATGAYPRLSLSFRLKRNIGYFILQTYMPSILITILSWVSFWINYDASAARVALGITTVLTMTTINTHLRETLPKIPYVKAIDMYLMG 312          
BLAST of Neur_chan_LBD domain-containing protein vs. Ensembl Human
Match: GABRB3 (gamma-aminobutyric acid type A receptor beta3 subunit [Source:HGNC Symbol;Acc:HGNC:4083])

HSP 1 Score: 52.373 bits (124), Expect = 1.203e-6
Identity = 58/257 (22.57%), Postives = 110/257 (42.80%), Query Frame = 3
Query:  261 VCVVF-LKIGEIDTIKE---QYAADILIKCKWREPRLDHNTEKLEYDWANSWTPKLYIENT--IGEAKEHVYQMIIFNE----NQHAFLCEKRRVSGIFLENLELNHFPFDVQDLTITIASNLPSTEIRLVNDPDETHRVNKQSFVDEQEWYLFKHIETEQKELAYEYADPSSVKPAISVKCRAARRPAYFIWNIFLVTFLICSLSLVTFAVDKSLPQNRLQXXXXXXXXXXXXXXXXNQCLPKISYLTYLDKYVIS 1001
            VCV   + I  ID + E    Y   +  +  WR+ RL ++   L     N    +L++ +T  + + K  V+ + + N     +    +    R++      ++L  +P D Q+ T+ I S   +T+     D +   R   ++    +   L +    E + ++      +   P +S+  R  R   YFI   ++ + LI  LS V+F ++      R+ L  T VLT+      + + LPKI Y+  +D Y++ 
Sbjct:   28 VCVGMNIDIASIDMVSEVNMDYTLTMYFQQYWRDKRLAYSGIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTD-----DIEFYWRGGDKAVTGVERIELPQFSIVEHRLVSRNVVFATGAYPRLSLSFRLKRNIGYFILQTYMPSILITILSWVSFWINYDASAARVALGITTVLTMTTINTHLRETLPKIPYVKAIDMYLMG 279          
BLAST of Neur_chan_LBD domain-containing protein vs. Ensembl Human
Match: GABRB3 (gamma-aminobutyric acid type A receptor beta3 subunit [Source:HGNC Symbol;Acc:HGNC:4083])

HSP 1 Score: 52.373 bits (124), Expect = 1.406e-6
Identity = 58/257 (22.57%), Postives = 110/257 (42.80%), Query Frame = 3
Query:  261 VCVVF-LKIGEIDTIKE---QYAADILIKCKWREPRLDHNTEKLEYDWANSWTPKLYIENT--IGEAKEHVYQMIIFNE----NQHAFLCEKRRVSGIFLENLELNHFPFDVQDLTITIASNLPSTEIRLVNDPDETHRVNKQSFVDEQEWYLFKHIETEQKELAYEYADPSSVKPAISVKCRAARRPAYFIWNIFLVTFLICSLSLVTFAVDKSLPQNRLQXXXXXXXXXXXXXXXXNQCLPKISYLTYLDKYVIS 1001
            VCV   + I  ID + E    Y   +  +  WR+ RL ++   L     N    +L++ +T  + + K  V+ + + N     +    +    R++      ++L  +P D Q+ T+ I S   +T+     D +   R   ++    +   L +    E + ++      +   P +S+  R  R   YFI   ++ + LI  LS V+F ++      R+ L  T VLT+      + + LPKI Y+  +D Y++ 
Sbjct:  117 VCVGMNIDIASIDMVSEVNMDYTLTMYFQQYWRDKRLAYSGIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTD-----DIEFYWRGGDKAVTGVERIELPQFSIVEHRLVSRNVVFATGAYPRLSLSFRLKRNIGYFILQTYMPSILITILSWVSFWINYDASAARVALGITTVLTMTTINTHLRETLPKIPYVKAIDMYLMG 368          
BLAST of Neur_chan_LBD domain-containing protein vs. Ensembl Human
Match: GABRB3 (gamma-aminobutyric acid type A receptor beta3 subunit [Source:HGNC Symbol;Acc:HGNC:4083])

HSP 1 Score: 51.9878 bits (123), Expect = 1.407e-6
Identity = 58/257 (22.57%), Postives = 110/257 (42.80%), Query Frame = 3
Query:  261 VCVVF-LKIGEIDTIKE---QYAADILIKCKWREPRLDHNTEKLEYDWANSWTPKLYIENT--IGEAKEHVYQMIIFNE----NQHAFLCEKRRVSGIFLENLELNHFPFDVQDLTITIASNLPSTEIRLVNDPDETHRVNKQSFVDEQEWYLFKHIETEQKELAYEYADPSSVKPAISVKCRAARRPAYFIWNIFLVTFLICSLSLVTFAVDKSLPQNRLQXXXXXXXXXXXXXXXXNQCLPKISYLTYLDKYVIS 1001
            VCV   + I  ID + E    Y   +  +  WR+ RL ++   L     N    +L++ +T  + + K  V+ + + N     +    +    R++      ++L  +P D Q+ T+ I S   +T+     D +   R   ++    +   L +    E + ++      +   P +S+  R  R   YFI   ++ + LI  LS V+F ++      R+ L  T VLT+      + + LPKI Y+  +D Y++ 
Sbjct:   61 VCVGMNIDIASIDMVSEVNMDYTLTMYFQQYWRDKRLAYSGIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTD-----DIEFYWRGGDKAVTGVERIELPQFSIVEHRLVSRNVVFATGAYPRLSLSFRLKRNIGYFILQTYMPSILITILSWVSFWINYDASAARVALGITTVLTMTTINTHLRETLPKIPYVKAIDMYLMG 312          
BLAST of Neur_chan_LBD domain-containing protein vs. Ensembl Human
Match: GLRA1 (glycine receptor alpha 1 [Source:HGNC Symbol;Acc:HGNC:4326])

HSP 1 Score: 50.8322 bits (120), Expect = 3.177e-6
Identity = 61/267 (22.85%), Postives = 120/267 (44.94%), Query Frame = 3
Query:  264 CVVFL-KIGEIDTIKEQYAADILIKCKWREPRLDHN---TEKLEYDWA---NSWTPKLYIENTIGEAKEHVYQMIIFNE----NQHAFLCEKRRVSGIFLENLELNHFPFDVQDLTITIASNLPSTEIRLVNDPDETHRVNKQSFVDEQEWYLFKHIETEQKELAYEYADPSSVK-PAISVKCRAARRPAYFIWNIFLVTFLICSLSLVTFAVDKSLPQNRLQXXXXXXXXXXXXXXXXNQCLPKISYLTYLDKYV-ISSLFILTVI 1025
            C +F+   G I      Y  +I ++ +W +PRL +N    + L+ D +   + W P L+  N   E   H +++   N+    +++  +    R++      ++L +FP DVQ   + + S    T   L+ +  E   V     +      L + I  E+K+L Y     ++ K   I  +    R+  Y++  +++ + LI  LS ++F ++      R+ L  T VLT+          LPK+SY+  +D ++ +  LF+ + +
Sbjct:   69 CNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYNEYPDDSLDLDPSMLDSIWKPDLFFAN---EKGAHFHEITTDNKLLRISRNGNVLYSIRITLTLACPMDLKNFPMDVQTCIMQLES-FGYTMNDLIFEWQEQGAVQVADGLT-----LPQFILKEEKDLRYCTKHYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWISFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSAL 326          
BLAST of Neur_chan_LBD domain-containing protein vs. Ensembl Celegans
Match: deg-3 (Acetylcholine receptor subunit alpha-type deg-3 [Source:UniProtKB/Swiss-Prot;Acc:P54244])

HSP 1 Score: 52.7582 bits (125), Expect = 4.229e-7
Identity = 53/230 (23.04%), Postives = 100/230 (43.48%), Query Frame = 3
Query:  252 QVYVCVVFLKIGEIDTIKEQYAADILIKCKWREPRLDHNTEKLEYDWANS--------WTPKLYIENTIGEAKEHVYQMIIFNENQHAFLCEKRR-----VSGIFLENLELN--HFPFDVQDLTITIASNLPSTEIRLVNDPDETHRVNKQSFVDEQEWYLFKHIETEQKELAYEYADPSSVKPAISVKCRAARRPAYFIWNIFLVTFLICSLSLVTFAVDKSLPQNRLQ 896
            +V++ +   +I E+D   +    ++ +  KWR+  LD N    EY   NS        W P  Y+ N++  +++   + +      + +  EK          I+     LN   FP+D Q+ T+TI+S    T  +   D      V+ QSF+  +EW + K  +  + E  Y+YA  +     +       R+P Y++ N+ + T +I  +++  F    S   +R +
Sbjct:   79 KVHISISLYQIIEVDEPSQNIKLNVWMIQKWRDEYLDWNPN--EYGMINSTIIPFHHLWIPDTYLYNSVKMSRDETERYMNIQATSNYWKGEKGAELSFLYPAIYTITCRLNIRFFPYDRQNCTLTISS---WTNSKSALDYYADTEVSMQSFIPNEEWQV-KSFKIHRHE--YKYACCAEPWVILQASLVIQRKPLYYLVNLIIPTSIITLVAITGFFTPASTDDDRTE 300          
BLAST of Neur_chan_LBD domain-containing protein vs. Ensembl Celegans
Match: deg-3 (Acetylcholine receptor subunit alpha-type deg-3 [Source:UniProtKB/Swiss-Prot;Acc:P54244])

HSP 1 Score: 52.7582 bits (125), Expect = 4.229e-7
Identity = 53/230 (23.04%), Postives = 100/230 (43.48%), Query Frame = 3
Query:  252 QVYVCVVFLKIGEIDTIKEQYAADILIKCKWREPRLDHNTEKLEYDWANS--------WTPKLYIENTIGEAKEHVYQMIIFNENQHAFLCEKRR-----VSGIFLENLELN--HFPFDVQDLTITIASNLPSTEIRLVNDPDETHRVNKQSFVDEQEWYLFKHIETEQKELAYEYADPSSVKPAISVKCRAARRPAYFIWNIFLVTFLICSLSLVTFAVDKSLPQNRLQ 896
            +V++ +   +I E+D   +    ++ +  KWR+  LD N    EY   NS        W P  Y+ N++  +++   + +      + +  EK          I+     LN   FP+D Q+ T+TI+S    T  +   D      V+ QSF+  +EW + K  +  + E  Y+YA  +     +       R+P Y++ N+ + T +I  +++  F    S   +R +
Sbjct:   79 KVHISISLYQIIEVDEPSQNIKLNVWMIQKWRDEYLDWNPN--EYGMINSTIIPFHHLWIPDTYLYNSVKMSRDETERYMNIQATSNYWKGEKGAELSFLYPAIYTITCRLNIRFFPYDRQNCTLTISS---WTNSKSALDYYADTEVSMQSFIPNEEWQV-KSFKIHRHE--YKYACCAEPWVILQASLVIQRKPLYYLVNLIIPTSIITLVAITGFFTPASTDDDRTE 300          
BLAST of Neur_chan_LBD domain-containing protein vs. Ensembl Celegans
Match: lgc-8 (Ligand-Gated ion Channel [Source:UniProtKB/TrEMBL;Acc:Q6BEQ0])

HSP 1 Score: 51.2174 bits (121), Expect = 1.060e-6
Identity = 46/198 (23.23%), Postives = 91/198 (45.96%), Query Frame = 3
Query:  534 NLELNHFPFDVQDLTITIAS-NLPSTEIRLVNDPDETHRVNKQSFVDEQEWYLFKHI-----ETEQKELAYEYADPSSVKPAISVKCRAARRPAYFIWNIFLVTFLI---CSLSLVTFAVDKSLPQNRLQXXXXXXXXXXXXXXXXNQCLPKISYLTYLDKYVISSLFILTVICVWHGMIVVIERFASKSEYDLPKDM 1100
            ++ +N FP+D Q   I +   +    E+  +   D         F    EW  F+ I     ETE  ++ + +   S V  A++VK    RRP +++W + + T++I   C   L T   +  L + R+ L  T +L+      +V   +PK S L  L  ++++ +F++ +  ++  +++ + + A   E+  P  M
Sbjct:  153 DMNINEFPYDQQTCMIKMGPWSYTMKEVTCIVGGDIERNETTGKFQGNSEWD-FEGIVSSVGETEDPDVNFTF---SEVHFALTVK----RRPQFYVWVLLIPTYIITVVCIFGLFTPTANHGLREERVNLGITTLLSSAVILQIVANAMPKTSELPLLGNFILAEIFVVAIGVLFAVLVLTLHQRAHTREWRPPAWM 342          
BLAST of Neur_chan_LBD domain-containing protein vs. Ensembl Celegans
Match: lgc-18 (Ligand-Gated ion Channel [Source:UniProtKB/TrEMBL;Acc:Q22084])

HSP 1 Score: 50.8322 bits (120), Expect = 1.339e-6
Identity = 58/267 (21.72%), Postives = 118/267 (44.19%), Query Frame = 3
Query:  261 VCVVFLKIGEIDTIKEQYAADILIKCKWREPR------LDHNTEKLEYDWANSWTPKLYI--ENTIGEAKEHVYQMIIFNENQHAFLCEKRRVSGIFLENLELNHFPFDVQDLTITIASNLPSTEIRLVNDPDETHRVNKQSFVDEQEWYLFKHIETEQKELAYE-----YADPSSVKPAISVKCRAARRPAYFIWNIFLVTFLICSLSLVTFAVDKSLPQNRLQXXXXXXXXXXXXXXXXNQCLPKISYLTYLDKYVISSLFILTV 1022
            V + +LK+ E+   +E+ +  + +   W +PR      L  + + L       W+P L +   N I + ++  ++M+      H +     ++S      L+++ FP+D Q  T  I  N+P   ++ V    + +    +  ++   W    + E E   L +      Y D        + + R  R P Y+I+ I   +F+I +LS++   + K+   ++L +  T ++T+     V+   +PK   +  L  Y+I +LFI+ V
Sbjct:   76 VSLYYLKLVEVIEPEEKVSVVLEMAEYWYDPRIAWDSSLYGDIKMLHMRQDKVWSPTLSLFRINDIADFRDPDFRMVCVENTGHTYTTLSVKIS--LNCPLDVSMFPYDSQ--TCRIQFNMPLFFMQQVEMFSQIY----EGILNSTVWEKMGNSEWELANLTHSVELLSYGDGLGDMQLATFEIRIRRNPMYYIYMIIFPSFIINALSIIGVFLKKTDKMSKLNVGLTNIMTMTFILGVMADKIPKTGSIPLLGIYIIVNLFIMIV 334          
BLAST of Neur_chan_LBD domain-containing protein vs. Ensembl Celegans
Match: lgc-9 (Ligand-Gated ion Channel [Source:UniProtKB/TrEMBL;Acc:O44452])

HSP 1 Score: 50.8322 bits (120), Expect = 1.423e-6
Identity = 60/220 (27.27%), Postives = 100/220 (45.45%), Query Frame = 3
Query:  234 QNNRKRQVYVCVVFLKIGEIDTIKE-QYAADILIKC--KWREPRL-----DHNT-EKLEYDWANSWTPKLYIENTIGEAKEHV----YQMIIFNENQHAFLCEKRRVSGIFLENLELNHFPFDVQDLTITIASNLPSTEIRLVNDPDETHRVNKQSFVDEQEWYLFKHIETEQKELAYEYADPSSVKPAISVKCRAARRPAYFIWNIFLVTFLICSLSLV 854
            ++NR   V++ +V   +G +  ++E Q  A  +I    KWR+P+L     DH+   ++    +  W PKL+I N++ + K+ +    Y + I     H  +   + VS +   N++L  FPFD Q   I +AS L S E   VN    T       F    EW +      + K     + +    +  +       RRP Y+I  I + TFLI +LS++
Sbjct:   61 ESNRPVIVHMTIV---LGILTEVRENQQVASFVISHVQKWRDPKLAWNPADHSGLTQVVMPRSLVWVPKLFIYNSM-DTKDMLTDDRYDVRI-QHTGHVKVNSPQFVSTLCRINIDL--FPFDTQFCAIALASPLLSVEEMDVN---ATQPPVDSYFSGNAEWQVMNVTVKQMK-----FMEEGEYRAEVHYILHLNRRPTYYITVIVVPTFLISALSIL 265          
BLAST of Neur_chan_LBD domain-containing protein vs. Ensembl Fly
Match: Rdl (gene:FBgn0004244 transcript:FBtr0333836)

HSP 1 Score: 51.6026 bits (122), Expect = 1.317e-6
Identity = 66/287 (23.00%), Postives = 121/287 (42.16%), Query Frame = 3
Query:  192 DNYSVNNDERIFGDQNNRKRQVYVCVVFLKIGEIDTIKEQYAADILIKCKWREPRLDH----NTEKLEYDW---ANSWTPKLYIENTIGEAKEHVYQMIIFNE----NQHAFLCEKRRVSGIFLENLELNHFPFDVQDLTITIAS-NLPSTEIRLVNDPDETHRVNKQSFVDEQEWYLFKHIETEQKELAYEYADPSSVKPAISVKCRAARRPAYFIWNIFLVTFLICSLSLVTFAVDKSLPQNRLQXXXXXXXXXXXXXXXXNQCLPKISYLTYLDKYVISSLFIL 1016
            D++SV+ D+R+  +      +V V +  L I  +  +K  +  D   +  W +PRL +      E L        N W P  +  N   E + + +     NE    +    +    R++      + L +FP D Q   I I S      +IR     D    V   S V+  ++ +  H     ++ A E    +     ++ + +  R   Y++  I++ + LI  +S V+F ++++    R+ L  T VLT+       N  LPKISY+  +D Y + + F++
Sbjct:   64 DSFSVSYDKRVRPNYGGPPVEVGVTMYVLSISSLSEVKMDFTLDFYFRQFWTDPRLAYRKRPGVETLSVGSEFIKNIWVPDTFFVN---EKQSYFHIATTSNEFIRVHHSGSITRSIRLTITASCPMNLQYFPMDRQLCHIEIESFGYTMRDIRYFWR-DGLSSVGMSSEVELPQFRVLGH-----RQRATEINLTTGNYSRLACEIQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGVTTVLTMTTLMSSTNAALPKISYVKSIDVY-LGTCFVM 340          
BLAST of Neur_chan_LBD domain-containing protein vs. Ensembl Fly
Match: Rdl (gene:FBgn0004244 transcript:FBtr0309054)

HSP 1 Score: 51.2174 bits (121), Expect = 1.357e-6
Identity = 66/287 (23.00%), Postives = 121/287 (42.16%), Query Frame = 3
Query:  192 DNYSVNNDERIFGDQNNRKRQVYVCVVFLKIGEIDTIKEQYAADILIKCKWREPRLDH----NTEKLEYDW---ANSWTPKLYIENTIGEAKEHVYQMIIFNE----NQHAFLCEKRRVSGIFLENLELNHFPFDVQDLTITIAS-NLPSTEIRLVNDPDETHRVNKQSFVDEQEWYLFKHIETEQKELAYEYADPSSVKPAISVKCRAARRPAYFIWNIFLVTFLICSLSLVTFAVDKSLPQNRLQXXXXXXXXXXXXXXXXNQCLPKISYLTYLDKYVISSLFIL 1016
            D++SV+ D+R+  +      +V V +  L I  +  +K  +  D   +  W +PRL +      E L        N W P  +  N   E + + +     NE    +    +    R++      + L +FP D Q   I I S      +IR     D    V   S V+  ++ +  H     ++ A E    +     ++ + +  R   Y++  I++ + LI  +S V+F ++++    R+ L  T VLT+       N  LPKISY+  +D Y + + F++
Sbjct:   64 DSFSVSYDKRVRPNYGGPPVEVGVTMYVLSISSLSEVKMDFTLDFYFRQFWTDPRLAYRKRPGVETLSVGSEFIKNIWVPDTFFVN---EKQSYFHIATTSNEFIRVHHSGSITRSIRLTITASCPMNLQYFPMDRQLCHIEIESFGYTMRDIRYFWR-DGLSSVGMSSEVELPQFRVLGH-----RQRATEINLTTGNYSRLACEIQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGVTTVLTMTTLMSSTNAALPKISYVKSIDVY-LGTCFVM 340          
BLAST of Neur_chan_LBD domain-containing protein vs. Ensembl Fly
Match: Rdl (gene:FBgn0004244 transcript:FBtr0333835)

HSP 1 Score: 51.2174 bits (121), Expect = 1.552e-6
Identity = 65/287 (22.65%), Postives = 123/287 (42.86%), Query Frame = 3
Query:  192 DNYSVNNDERIFGDQNNRKRQVYVCVVFLKIGEIDTIKEQYAADILIKCKWREPRLDH----NTEKLEYDW---ANSWTPKLYIENTIGEAKEHVYQMIIFNE----NQHAFLCEKRRVSGIFLENLELNHFPFDVQDLTITIAS-NLPSTEIRLVNDPDETHRVNKQSFVDEQEWYLFKHIETEQKELAYEYADPSSVKPAISVKCRAARRPAYFIWNIFLVTFLICSLSLVTFAVDKSLPQNRLQXXXXXXXXXXXXXXXXNQCLPKISYLTYLDKYVISSLFIL 1016
            D++SV+ D+R+  +      +V V +  L I  +  +K  +  D   +  W +PRL +      E L        N W P  +  N   E + + +     NE    +    +    R++      + L +FP D Q   I I S      +IR   + +  + V   S V   ++ +  H     ++ A E +  +     ++ + +  R   Y++  I++ + LI  +S V+F ++++    R+ L  T VLT+       N  LPKISY+  +D Y + + F++
Sbjct:   64 DSFSVSYDKRVRPNYGGPPVEVGVTMYVLSISSLSEVKMDFTLDFYFRQFWTDPRLAYRKRPGVETLSVGSEFIKNIWVPDTFFVN---EKQSYFHIATTSNEFIRVHHSGSITRSIRLTITASCPMNLQYFPMDRQLCHIEIESFGYTMRDIRYKWN-EGPNSVGVSSEVSLPQFKVLGH-----RQRAMEISLTTGNYSRLACEIQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGVTTVLTMTTLMSSTNAALPKISYVKSIDVY-LGTCFVM 340          
BLAST of Neur_chan_LBD domain-containing protein vs. Ensembl Fly
Match: Rdl (gene:FBgn0004244 transcript:FBtr0076534)

HSP 1 Score: 51.2174 bits (121), Expect = 1.552e-6
Identity = 65/287 (22.65%), Postives = 123/287 (42.86%), Query Frame = 3
Query:  192 DNYSVNNDERIFGDQNNRKRQVYVCVVFLKIGEIDTIKEQYAADILIKCKWREPRLDH----NTEKLEYDW---ANSWTPKLYIENTIGEAKEHVYQMIIFNE----NQHAFLCEKRRVSGIFLENLELNHFPFDVQDLTITIAS-NLPSTEIRLVNDPDETHRVNKQSFVDEQEWYLFKHIETEQKELAYEYADPSSVKPAISVKCRAARRPAYFIWNIFLVTFLICSLSLVTFAVDKSLPQNRLQXXXXXXXXXXXXXXXXNQCLPKISYLTYLDKYVISSLFIL 1016
            D++SV+ D+R+  +      +V V +  L I  +  +K  +  D   +  W +PRL +      E L        N W P  +  N   E + + +     NE    +    +    R++      + L +FP D Q   I I S      +IR   + +  + V   S V   ++ +  H     ++ A E +  +     ++ + +  R   Y++  I++ + LI  +S V+F ++++    R+ L  T VLT+       N  LPKISY+  +D Y + + F++
Sbjct:   64 DSFSVSYDKRVRPNYGGPPVEVGVTMYVLSISSLSEVKMDFTLDFYFRQFWTDPRLAYRKRPGVETLSVGSEFIKNIWVPDTFFVN---EKQSYFHIATTSNEFIRVHHSGSITRSIRLTITASCPMNLQYFPMDRQLCHIEIESFGYTMRDIRYKWN-EGPNSVGVSSEVSLPQFKVLGH-----RQRAMEISLTTGNYSRLACEIQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGVTTVLTMTTLMSSTNAALPKISYVKSIDVY-LGTCFVM 340          
BLAST of Neur_chan_LBD domain-containing protein vs. Ensembl Fly
Match: ort (gene:FBgn0003011 transcript:FBtr0083784)

HSP 1 Score: 49.2914 bits (116), Expect = 6.043e-6
Identity = 75/302 (24.83%), Postives = 131/302 (43.38%), Query Frame = 3
Query:  255 VYVCVVFLKIGEIDTIKEQYAADILIKCKWREPRL---DHNTEK---LEYDW-ANSWTPKLYIENTIGEAKEHVYQMIIFNENQHAFLCEKRRVSGIFLENLELNH------FPFDVQDLTITIASNLPSTEIRLVNDPDETHRVNKQSFVDEQEWYLFKHIETEQKELAY-EYADPSSVKPAISVKC-----RAARRPAYFIWNIFLVTFLICSLSLVTFAVDKSLPQNRLQXXXXXXXXXXXXXXXXNQCLPKISYLTYLDKYV-ISSLFILTVICVWHGMIVVIERFASKSEYDLPKDM 1100
            VY  V  + +  ID     Y AD+     W++ RL   ++ T++   LE DW  N W P  + +N    AK   +Q +    N + +L + + +  +    L+L+       +P D Q+  + + S L  T   L+   D T  +     VDE       +IE  Q  L   E AD + V    +  C        RR  Y+++N ++ T +I  +S V+F +       R+ L  T +LTL          LP +SYL  +D ++ + ++F+   +  +  + +V+      S+  +PK M
Sbjct:   55 VYFHVTVMGLDSIDENSMTYVADVFFAQTWKDHRLRLPENMTQEYRLLEVDWLKNMWRPDSFFKN----AKSVTFQTMTI-PNHYMWLYKDKTILYMVKLTLKLSCIMNFAIYPHDTQECKLQMES-LSHTTDDLIFQWDPTTPL----VVDE-------NIELPQVALIRNETADCTQVYSTGNFTCLEVVFTLKRRLVYYVFNTYIPTCMIVIMSWVSFWIKPEAAPARVTLGVTSLLTLSTQHAKSQSSLPPVSYLKAVDAFMSVCTVFVFMALMEYCLINIVL------SDTPIPKPM 333          
BLAST of Neur_chan_LBD domain-containing protein vs. Ensembl Zebrafish
Match: gabrg1 (gamma-aminobutyric acid type A receptor gamma1 subunit [Source:ZFIN;Acc:ZDB-GENE-141215-66])

HSP 1 Score: 51.9878 bits (123), Expect = 9.163e-7
Identity = 66/278 (23.74%), Postives = 111/278 (39.93%), Query Frame = 3
Query:  213 DERIFGDQNNRKRQVYVCVVFLKIGEIDTIKEQYAADILIKCKWREPRLDHNTEKLEYDWANSWTPKLYIENTIGEAKEHVYQMIIFNENQHAFLCEKRRVSGIFLEN------LELNHFPFDVQDLTITIAS-NLPSTEIRLVNDPDETHRVNKQSF--VDEQEWYLFKHIETEQKELAYEYADPSSVKPAISVKCRAARRPAYFIWNIFLVTFLICSLSLVTFAVDKSLPQNRLQXXXXXXXXXXXXXXXXNQCLPKISYLTYLDKYVISSLFILT 1019
            D ++  D   R   +   V    IG +D I  +Y  DI     W + RL  N+        ++   K++I +T            I   N+   L    RV             L+L++FP D     +  +S   P  EI+        +R  ++S    D++ W L++      +  +      S     +++    +RR  YF    ++   +I  LS V+F ++K     R  L  T VLT+     +  + LPK+SY+T +D +V S  FI T
Sbjct:   72 DNKLRPDIGVRPTVIETAVYVNSIGPVDPINMEYTIDIFFAQTWYDSRLKFNSSMKLLMLNSNMVGKIWIPDTFFRNSRKSDAHWITTPNRLLRLWSNGRVMYTLRLTINAECYLKLHNFPMDEHSCPLEFSSYGYPKNEIQ--------YRWQRRSVEVADQRYWRLYQFAFVGLRNSSDVANTQSGEYVVMTIFFDLSRRMGYFTIQTYIPCSMIVVLSWVSFWINKDAVPARTSLGITTVLTMTTLSTISRKSLPKVSYVTAMDLFV-SVCFIFT 340          
BLAST of Neur_chan_LBD domain-containing protein vs. Ensembl Zebrafish
Match: gabrg1 (gamma-aminobutyric acid type A receptor gamma1 subunit [Source:ZFIN;Acc:ZDB-GENE-141215-66])

HSP 1 Score: 51.9878 bits (123), Expect = 1.000e-6
Identity = 66/278 (23.74%), Postives = 111/278 (39.93%), Query Frame = 3
Query:  213 DERIFGDQNNRKRQVYVCVVFLKIGEIDTIKEQYAADILIKCKWREPRLDHNTEKLEYDWANSWTPKLYIENTIGEAKEHVYQMIIFNENQHAFLCEKRRVSGIFLEN------LELNHFPFDVQDLTITIAS-NLPSTEIRLVNDPDETHRVNKQSF--VDEQEWYLFKHIETEQKELAYEYADPSSVKPAISVKCRAARRPAYFIWNIFLVTFLICSLSLVTFAVDKSLPQNRLQXXXXXXXXXXXXXXXXNQCLPKISYLTYLDKYVISSLFILT 1019
            D ++  D   R   +   V    IG +D I  +Y  DI     W + RL  N+        ++   K++I +T            I   N+   L    RV             L+L++FP D     +  +S   P  EI+        +R  ++S    D++ W L++      +  +      S     +++    +RR  YF    ++   +I  LS V+F ++K     R  L  T VLT+     +  + LPK+SY+T +D +V S  FI T
Sbjct:   72 DNKLRPDIGVRPTVIETAVYVNSIGPVDPINMEYTIDIFFAQTWYDSRLKFNSSMKLLMLNSNMVGKIWIPDTFFRNSRKSDAHWITTPNRLLRLWSNGRVMYTLRLTINAECYLKLHNFPMDEHSCPLEFSSYGYPKNEIQ--------YRWQRRSVEVADQRYWRLYQFAFVGLRNSSDVANTQSGEYVVMTIFFDLSRRMGYFTIQTYIPCSMIVVLSWVSFWINKDAVPARTSLGITTVLTMTTLSTISRKSLPKVSYVTAMDLFV-SVCFIFT 340          
BLAST of Neur_chan_LBD domain-containing protein vs. Ensembl Zebrafish
Match: glra1 (glycine receptor, alpha 1 [Source:NCBI gene;Acc:30676])

HSP 1 Score: 51.6026 bits (122), Expect = 1.205e-6
Identity = 62/267 (23.22%), Postives = 120/267 (44.94%), Query Frame = 3
Query:  261 VCVVFL-KIGEIDTIKEQYAADILIKCKWREPRL---DHNTEKLEYDWA---NSWTPKLYIENTIGEAKEHVY---QMIIFNENQHAFLCEKRRVSGIFLENLELNHFPFDVQDLTITIASNLPSTEIRLVNDPDETHRVNKQSFVDEQEWYLFKHIETEQKELAYEYADPSSVK-PAISVKCRAARRPAYFIWNIFLVTFLICSLSLVTFAVDKSLPQNRLQXXXXXXXXXXXXXXXXNQCLPKISYLTYLDKYV-ISSLFILTVI 1025
             C +F+   G I      Y  +I ++ +W +PRL   ++  + L+ D +   + W P L+  N  G     V    +++  ++N +       R++ +    ++L +FP DVQ   + + S    T   L+ + DE   V     +      L + I  E+K+L Y     ++ K   I  +    R+  Y++  +++ + LI  LS V+F ++      R+ L  T VLT+          LPK+SY+  +D ++ +  LF+ + +
Sbjct:   64 TCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRISKNGNVLY--SIRITLVLACPMDLKNFPMDVQTCIMQLES-FGYTMNDLIFEWDEKGAVQVADGLT-----LPQFILKEEKDLRYCTKHYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSAL 322          
BLAST of Neur_chan_LBD domain-containing protein vs. Ensembl Zebrafish
Match: glra1 (glycine receptor, alpha 1 [Source:NCBI gene;Acc:30676])

HSP 1 Score: 51.6026 bits (122), Expect = 1.332e-6
Identity = 62/267 (23.22%), Postives = 120/267 (44.94%), Query Frame = 3
Query:  261 VCVVFL-KIGEIDTIKEQYAADILIKCKWREPRL---DHNTEKLEYDWA---NSWTPKLYIENTIGEAKEHVY---QMIIFNENQHAFLCEKRRVSGIFLENLELNHFPFDVQDLTITIASNLPSTEIRLVNDPDETHRVNKQSFVDEQEWYLFKHIETEQKELAYEYADPSSVK-PAISVKCRAARRPAYFIWNIFLVTFLICSLSLVTFAVDKSLPQNRLQXXXXXXXXXXXXXXXXNQCLPKISYLTYLDKYV-ISSLFILTVI 1025
             C +F+   G I      Y  +I ++ +W +PRL   ++  + L+ D +   + W P L+  N  G     V    +++  ++N +       R++ +    ++L +FP DVQ   + + S    T   L+ + DE   V     +      L + I  E+K+L Y     ++ K   I  +    R+  Y++  +++ + LI  LS V+F ++      R+ L  T VLT+          LPK+SY+  +D ++ +  LF+ + +
Sbjct:   77 TCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRISKNGNVLY--SIRITLVLACPMDLKNFPMDVQTCIMQLES-FGYTMNDLIFEWDEKGAVQVADGLT-----LPQFILKEEKDLRYCTKHYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSAL 335          
BLAST of Neur_chan_LBD domain-containing protein vs. Ensembl Zebrafish
Match: glra1 (glycine receptor, alpha 1 [Source:NCBI gene;Acc:30676])

HSP 1 Score: 51.6026 bits (122), Expect = 1.347e-6
Identity = 62/267 (23.22%), Postives = 120/267 (44.94%), Query Frame = 3
Query:  261 VCVVFL-KIGEIDTIKEQYAADILIKCKWREPRL---DHNTEKLEYDWA---NSWTPKLYIENTIGEAKEHVY---QMIIFNENQHAFLCEKRRVSGIFLENLELNHFPFDVQDLTITIASNLPSTEIRLVNDPDETHRVNKQSFVDEQEWYLFKHIETEQKELAYEYADPSSVK-PAISVKCRAARRPAYFIWNIFLVTFLICSLSLVTFAVDKSLPQNRLQXXXXXXXXXXXXXXXXNQCLPKISYLTYLDKYV-ISSLFILTVI 1025
             C +F+   G I      Y  +I ++ +W +PRL   ++  + L+ D +   + W P L+  N  G     V    +++  ++N +       R++ +    ++L +FP DVQ   + + S    T   L+ + DE   V     +      L + I  E+K+L Y     ++ K   I  +    R+  Y++  +++ + LI  LS V+F ++      R+ L  T VLT+          LPK+SY+  +D ++ +  LF+ + +
Sbjct:   79 TCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRISKNGNVLY--SIRITLVLACPMDLKNFPMDVQTCIMQLES-FGYTMNDLIFEWDEKGAVQVADGLT-----LPQFILKEEKDLRYCTKHYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSAL 337          
BLAST of Neur_chan_LBD domain-containing protein vs. Ensembl Mouse
Match: Gabrb3 (gamma-aminobutyric acid (GABA) A receptor, subunit beta 3 [Source:MGI Symbol;Acc:MGI:95621])

HSP 1 Score: 52.7582 bits (125), Expect = 6.236e-7
Identity = 58/257 (22.57%), Postives = 110/257 (42.80%), Query Frame = 3
Query:  261 VCVVF-LKIGEIDTIKE---QYAADILIKCKWREPRLDHNTEKLEYDWANSWTPKLYIENT--IGEAKEHVYQMIIFNE----NQHAFLCEKRRVSGIFLENLELNHFPFDVQDLTITIASNLPSTEIRLVNDPDETHRVNKQSFVDEQEWYLFKHIETEQKELAYEYADPSSVKPAISVKCRAARRPAYFIWNIFLVTFLICSLSLVTFAVDKSLPQNRLQXXXXXXXXXXXXXXXXNQCLPKISYLTYLDKYVIS 1001
            VCV   + I  ID + E    Y   +  +  WR+ RL ++   L     N    +L++ +T  + + K  V+ + + N     +    +    R++      ++L  +P D Q+ T+ I S   +T+     D +   R   ++    +   L +    E + ++      +   P +S+  R  R   YFI   ++ + LI  LS V+F ++      R+ L  T VLT+      + + LPKI Y+  +D Y++ 
Sbjct:   61 VCVGMNIDIASIDMVSEVNMDYTLTMYFQQYWRDKRLAYSGIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTD-----DIEFYWRGGDKAVTGVERIELPQFSIVEHRLVSRNVVFATGAYPRLSLSFRLKRNIGYFILQTYMPSILITILSWVSFWINYDASAARVALGITTVLTMTTINTHLRETLPKIPYVKAIDMYLMG 312          
BLAST of Neur_chan_LBD domain-containing protein vs. Ensembl Mouse
Match: Gabrb3 (gamma-aminobutyric acid (GABA) A receptor, subunit beta 3 [Source:MGI Symbol;Acc:MGI:95621])

HSP 1 Score: 52.373 bits (124), Expect = 9.442e-7
Identity = 58/257 (22.57%), Postives = 110/257 (42.80%), Query Frame = 3
Query:  261 VCVVF-LKIGEIDTIKE---QYAADILIKCKWREPRLDHNTEKLEYDWANSWTPKLYIENT--IGEAKEHVYQMIIFNE----NQHAFLCEKRRVSGIFLENLELNHFPFDVQDLTITIASNLPSTEIRLVNDPDETHRVNKQSFVDEQEWYLFKHIETEQKELAYEYADPSSVKPAISVKCRAARRPAYFIWNIFLVTFLICSLSLVTFAVDKSLPQNRLQXXXXXXXXXXXXXXXXNQCLPKISYLTYLDKYVIS 1001
            VCV   + I  ID + E    Y   +  +  WR+ RL ++   L     N    +L++ +T  + + K  V+ + + N     +    +    R++      ++L  +P D Q+ T+ I S   +T+     D +   R   ++    +   L +    E + ++      +   P +S+  R  R   YFI   ++ + LI  LS V+F ++      R+ L  T VLT+      + + LPKI Y+  +D Y++ 
Sbjct:   83 VCVGMNIDIASIDMVSEVNMDYTLTMYFQQYWRDKRLAYSGIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTD-----DIEFYWRGGDKAVTGVERIELPQFSIVEHRLVSRNVVFATGAYPRLSLSFRLKRNIGYFILQTYMPSILITILSWVSFWINYDASAARVALGITTVLTMTTINTHLRETLPKIPYVKAIDMYLMG 334          
BLAST of Neur_chan_LBD domain-containing protein vs. Ensembl Mouse
Match: Gabrb3 (gamma-aminobutyric acid (GABA) A receptor, subunit beta 3 [Source:MGI Symbol;Acc:MGI:95621])

HSP 1 Score: 51.9878 bits (123), Expect = 1.073e-6
Identity = 58/257 (22.57%), Postives = 110/257 (42.80%), Query Frame = 3
Query:  261 VCVVF-LKIGEIDTIKE---QYAADILIKCKWREPRLDHNTEKLEYDWANSWTPKLYIENT--IGEAKEHVYQMIIFNE----NQHAFLCEKRRVSGIFLENLELNHFPFDVQDLTITIASNLPSTEIRLVNDPDETHRVNKQSFVDEQEWYLFKHIETEQKELAYEYADPSSVKPAISVKCRAARRPAYFIWNIFLVTFLICSLSLVTFAVDKSLPQNRLQXXXXXXXXXXXXXXXXNQCLPKISYLTYLDKYVIS 1001
            VCV   + I  ID + E    Y   +  +  WR+ RL ++   L     N    +L++ +T  + + K  V+ + + N     +    +    R++      ++L  +P D Q+ T+ I S   +T+     D +   R   ++    +   L +    E + ++      +   P +S+  R  R   YFI   ++ + LI  LS V+F ++      R+ L  T VLT+      + + LPKI Y+  +D Y++ 
Sbjct:   61 VCVGMNIDIASIDMVSEVNMDYTLTMYFQQYWRDKRLAYSGIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTD-----DIEFYWRGGDKAVTGVERIELPQFSIVEHRLVSRNVVFATGAYPRLSLSFRLKRNIGYFILQTYMPSILITILSWVSFWINYDASAARVALGITTVLTMTTINTHLRETLPKIPYVKAIDMYLMG 312          
BLAST of Neur_chan_LBD domain-containing protein vs. Ensembl Mouse
Match: Glra1 (glycine receptor, alpha 1 subunit [Source:MGI Symbol;Acc:MGI:95747])

HSP 1 Score: 51.6026 bits (122), Expect = 1.496e-6
Identity = 61/267 (22.85%), Postives = 120/267 (44.94%), Query Frame = 3
Query:  264 CVVFL-KIGEIDTIKEQYAADILIKCKWREPRLDHN---TEKLEYDWA---NSWTPKLYIENTIGEAKEHVYQMIIFNE----NQHAFLCEKRRVSGIFLENLELNHFPFDVQDLTITIASNLPSTEIRLVNDPDETHRVNKQSFVDEQEWYLFKHIETEQKELAYEYADPSSVK-PAISVKCRAARRPAYFIWNIFLVTFLICSLSLVTFAVDKSLPQNRLQXXXXXXXXXXXXXXXXNQCLPKISYLTYLDKYV-ISSLFILTVI 1025
            C +F+   G I      Y  +I ++ +W +PRL +N    + L+ D +   + W P L+  N   E   H +++   N+    +++  +    R++      ++L +FP DVQ   + + S    T   L+ +  E   V     +      L + I  E+K+L Y     ++ K   I  +    R+  Y++  +++ + LI  LS ++F ++      R+ L  T VLT+          LPK+SY+  +D ++ +  LF+ + +
Sbjct:   69 CNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYNEYPDDSLDLDPSMLDSIWKPDLFFAN---EKGAHFHEITTDNKLLRISRNGNVLYSIRITLTLACPMDLKNFPMDVQTCIMQLES-FGYTMNDLIFEWQEQGAVQVADGLT-----LPQFILKEEKDLRYCTKHYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWISFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSAL 326          
BLAST of Neur_chan_LBD domain-containing protein vs. Ensembl Mouse
Match: Glra1 (glycine receptor, alpha 1 subunit [Source:MGI Symbol;Acc:MGI:95747])

HSP 1 Score: 51.6026 bits (122), Expect = 1.555e-6
Identity = 61/267 (22.85%), Postives = 120/267 (44.94%), Query Frame = 3
Query:  264 CVVFL-KIGEIDTIKEQYAADILIKCKWREPRLDHN---TEKLEYDWA---NSWTPKLYIENTIGEAKEHVYQMIIFNE----NQHAFLCEKRRVSGIFLENLELNHFPFDVQDLTITIASNLPSTEIRLVNDPDETHRVNKQSFVDEQEWYLFKHIETEQKELAYEYADPSSVK-PAISVKCRAARRPAYFIWNIFLVTFLICSLSLVTFAVDKSLPQNRLQXXXXXXXXXXXXXXXXNQCLPKISYLTYLDKYV-ISSLFILTVI 1025
            C +F+   G I      Y  +I ++ +W +PRL +N    + L+ D +   + W P L+  N   E   H +++   N+    +++  +    R++      ++L +FP DVQ   + + S    T   L+ +  E   V     +      L + I  E+K+L Y     ++ K   I  +    R+  Y++  +++ + LI  LS ++F ++      R+ L  T VLT+          LPK+SY+  +D ++ +  LF+ + +
Sbjct:   69 CNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYNEYPDDSLDLDPSMLDSIWKPDLFFAN---EKGAHFHEITTDNKLLRISRNGNVLYSIRITLTLACPMDLKNFPMDVQTCIMQLES-FGYTMNDLIFEWQEQGAVQVADGLT-----LPQFILKEEKDLRYCTKHYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWISFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSAL 326          
BLAST of Neur_chan_LBD domain-containing protein vs. UniProt/SwissProt
Match: sp|P0C7B7|ELIC_DICCH (Cys-loop ligand-gated ion channel OS=Dickeya chrysanthemi OX=556 PE=1 SV=1)

HSP 1 Score: 67.0106 bits (162), Expect = 6.387e-11
Identity = 75/293 (25.60%), Postives = 139/293 (47.44%), Query Frame = 3
Query:  243 RKRQVYVCVVFLKIGEIDTIKEQYAADILIKCKWR-EPRLDHNTEKLEYD------WANS--WTPKLYIENTIGEAKEHVYQMIIFNENQHAFLCEKRRVSGIFLENLELNHFPFDVQDLTITIAS-NLPSTEIRLVNDPDETHRVNKQSFVDEQEWYLFKHIETEQKELAYEYADPSSVKPA------ISVKCRAARRPAYFIWNIFLVTFLICSLSLVTFAVDKSLPQNRLQXXXXXXXXXXXXXXXXNQCLPKISYLTYLDKYVIS---SLF--ILTVICVWHGMIVVIE 1058
            R   V V +   KI  ++T+++ Y  D  I  +W  +PR     + L  +      W N+  W P L   N +G       ++++F + +   +    R  G F  +++   FPFD Q   + +   +  + ++R  +    T  ++ +      EW++ +   T   ++ Y++   SSV+P       I+V+  A R P+Y++W+  L   LI + S   F ++      RLQ +FTL+LT+VA+ F  +  LP++ Y T +D+ +I+   S+F  IL +I   H   + +E
Sbjct:   10 RPVDVSVSIFINKIYGVNTLEQTYKVDGYIVAQWTGKPRKTPGDKPLIVENTQIERWINNGLWVPALEFINVVGSPDTGNKRLMLFPDGR---VIYNARFLGSFSNDMDFRLFPFDRQQFVLELEPFSYNNQQLRFSDIQVYTENIDNEEI---DEWWI-RKASTHISDIRYDHL--SSVQPNQNEFSRITVRIDAVRNPSYYLWSFILPLGLIIAASWSVFWLESF--SERLQTSFTLMLTVVAYAFYTSNILPRLPYTTVIDQMIIAGYGSIFAAILLIIFAHHRQAMGVE 291          
BLAST of Neur_chan_LBD domain-containing protein vs. UniProt/SwissProt
Match: sp|P54244|ACH3_CAEEL (Acetylcholine receptor subunit alpha-type deg-3 OS=Caenorhabditis elegans OX=6239 GN=deg-3 PE=1 SV=1)

HSP 1 Score: 52.7582 bits (125), Expect = 5.379e-6
Identity = 53/230 (23.04%), Postives = 100/230 (43.48%), Query Frame = 3
Query:  252 QVYVCVVFLKIGEIDTIKEQYAADILIKCKWREPRLDHNTEKLEYDWANS--------WTPKLYIENTIGEAKEHVYQMIIFNENQHAFLCEKRR-----VSGIFLENLELN--HFPFDVQDLTITIASNLPSTEIRLVNDPDETHRVNKQSFVDEQEWYLFKHIETEQKELAYEYADPSSVKPAISVKCRAARRPAYFIWNIFLVTFLICSLSLVTFAVDKSLPQNRLQ 896
            +V++ +   +I E+D   +    ++ +  KWR+  LD N    EY   NS        W P  Y+ N++  +++   + +      + +  EK          I+     LN   FP+D Q+ T+TI+S    T  +   D      V+ QSF+  +EW + K  +  + E  Y+YA  +     +       R+P Y++ N+ + T +I  +++  F    S   +R +
Sbjct:   79 KVHISISLYQIIEVDEPSQNIKLNVWMIQKWRDEYLDWNPN--EYGMINSTIIPFHHLWIPDTYLYNSVKMSRDETERYMNIQATSNYWKGEKGAELSFLYPAIYTITCRLNIRFFPYDRQNCTLTISS---WTNSKSALDYYADTEVSMQSFIPNEEWQV-KSFKIHRHE--YKYACCAEPWVILQASLVIQRKPLYYLVNLIIPTSIITLVAITGFFTPASTDDDRTE 300          
BLAST of Neur_chan_LBD domain-containing protein vs. UniProt/SwissProt
Match: sp|O93430|GLRA1_DANRE (Glycine receptor subunit alphaZ1 OS=Danio rerio OX=7955 GN=glra1 PE=1 SV=1)

HSP 1 Score: 51.6026 bits (122), Expect = 9.100e-6
Identity = 62/267 (23.22%), Postives = 120/267 (44.94%), Query Frame = 3
Query:  261 VCVVFL-KIGEIDTIKEQYAADILIKCKWREPRL---DHNTEKLEYDWA---NSWTPKLYIENTIGEAKEHVY---QMIIFNENQHAFLCEKRRVSGIFLENLELNHFPFDVQDLTITIASNLPSTEIRLVNDPDETHRVNKQSFVDEQEWYLFKHIETEQKELAYEYADPSSVK-PAISVKCRAARRPAYFIWNIFLVTFLICSLSLVTFAVDKSLPQNRLQXXXXXXXXXXXXXXXXNQCLPKISYLTYLDKYV-ISSLFILTVI 1025
             C +F+   G I      Y  +I ++ +W +PRL   ++  + L+ D +   + W P L+  N  G     V    +++  ++N +       R++ +    ++L +FP DVQ   + + S    T   L+ + DE   V     +      L + I  E+K+L Y     ++ K   I  +    R+  Y++  +++ + LI  LS V+F ++      R+ L  T VLT+          LPK+SY+  +D ++ +  LF+ + +
Sbjct:   64 TCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRISKNGNVLY--SIRITLVLACPMDLKNFPMDVQTCIMQLES-FGYTMNDLIFEWDEKGAVQVADGLT-----LPQFILKEEKDLRYCTKHYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSAL 322          
BLAST of Neur_chan_LBD domain-containing protein vs. TrEMBL
Match: A0A0V0J6K7 (Neur_chan_LBD domain-containing protein OS=Schistocephalus solidus OX=70667 GN=TR135000 PE=3 SV=1)

HSP 1 Score: 504.212 bits (1297), Expect = 9.885e-171
Identity = 251/342 (73.39%), Postives = 296/342 (86.55%), Query Frame = 3
Query:  243 RKRQVYVCVVFLKIGEIDTIKEQYAADILIKCKWREPRLDHNTEKLEYDWANSWTPKLYIENTIGEAKEHVYQMIIFNENQHAFLCEKRRVSGIFLENLELNHFPFDVQDLTITIASNLPSTEIRLVNDPDETHRVNKQSFVDEQEWYLFKHIETEQKELAYEYADPSSVKPAISVKCRAARRPAYFIWNIFLVTFLICSLSLVTFAVDKSLPQNRLQXXXXXXXXXXXXXXXXNQCLPKISYLTYLDKYVISSLFILTVICVWHGMIVVIERFASKSEYDLPKDMEIYVIIGMAVAFAGYNFGFIVMIYAVACKRRRIMKQRDKEYLERLQCQLKYKGART 1268
            +KRQVY+CV+FLKIGEIDTIKEQYAAD+LIK KWR+  +D    K EYDW ++WTPKLYIENTIGE +E ++Q I  NE  HAFL EKRRVSG+FLENLELNHFPFDVQDLTIT+ASNLPS+EIRL+NDPDE HR+NKQSFVDEQEWYL+KHI++EQ ELA EY + +SV+PA+SVKCRAARRPAYFIWNIFLVTFLICSLSLVTFAVD+S PQ+RLQLTFTLVLTLVAFKFVVNQCLPKISYLTYLDKY+ISSLF LT+IC+WHG I VIE+ A + +  L  DME+YVI+ + + +  +N GF++MIY VACKRRR MK +D EYLE+++CQ+  KG+R 
Sbjct:  288 KKRQVYLCVIFLKIGEIDTIKEQYAADVLIKAKWRDADMDTAGSK-EYDWLHNWTPKLYIENTIGEIREQIHQTIALNEFGHAFLVEKRRVSGVFLENLELNHFPFDVQDLTITVASNLPSSEIRLLNDPDEPHRINKQSFVDEQEWYLYKHIDSEQHELANEYIENASVRPALSVKCRAARRPAYFIWNIFLVTFLICSLSLVTFAVDRSQPQSRLQLTFTLVLTLVAFKFVVNQCLPKISYLTYLDKYIISSLFFLTLICIWHGGIAVIEKVAQRFDILLWADMELYVILLIGIGYFTFNVGFMLMIYCVACKRRRDMKSKDSEYLEKVKCQMNKKGSRA 628          
BLAST of Neur_chan_LBD domain-containing protein vs. TrEMBL
Match: A0A1S3HM70 (uncharacterized protein LOC106156405 isoform X5 OS=Lingula unguis OX=7574 GN=LOC106156405 PE=3 SV=1)

HSP 1 Score: 359.762 bits (922), Expect = 2.815e-117
Identity = 185/343 (53.94%), Postives = 252/343 (73.47%), Query Frame = 3
Query:  228 GDQNNRKRQVYVCVVFLKIGEIDTIKEQYAADILIKCKWREPRLDH---NTEKL----EYDWANSWTPKLYIENTIGEAKEHVYQMIIFNENQHAFLCEKRRVSGIFLENLELNHFPFDVQDLTITIASNLPSTEIRLVNDPDETHRVNKQSFVDEQEWYLFKHIETEQKELAYEYADPSSVKPAISVKCRAARRPAYFIWNIFLVTFLICSLSLVTFAVDKSLPQNRLQXXXXXXXXXXXXXXXXNQCLPKISYLTYLDKYVISSLFILTVICVWHGMIVVIERFASKSEYDLPKDMEIYVIIGMAVAFAGYNFGFIVMIYAVACKRRRIMKQRDKEYLERL 1235
             + ++ +  V VCV+FLK+GEIDT+KEQ++AD+L+K KWREP LD    N ++L    E D+   W PKL++ENT+G+ KE  ++ + F+    AF+CE +R+ G F+ENLELN FPFDVQDLT+T+ S  P++E+ L+ D  E HRV KQSF+DEQEW L+KH+E+E K LA  + DPS  +  +SVKCRAARRP +F+WNIFLVTFL CSLS  TF+V+ +LPQNRLQL+FTLVLT VAFKFV+NQ LP++SYLTYLDKY++ S+  L ++C WH ++  I+     S++D  K  E+  +  +AV + G+N G    IYA ACKRRRIMKQ+D+EY+E +
Sbjct:   46 AEPDHDRVTVEVCVIFLKLGEIDTLKEQFSADVLVKAKWREPELDRKGKNKDELIDEDEIDFEKYWNPKLFVENTVGDPKEVRWRTLAFSSEGDAFICENQRLKGTFVENLELNDFPFDVQDLTVTVTSERPASELNLIEDRMELHRVYKQSFIDEQEWSLYKHLESESKFLAEPHGDPSVKRVLLSVKCRAARRPWFFVWNIFLVTFLFCSLSFATFSVEYNLPQNRLQLSFTLVLTAVAFKFVINQSLPRVSYLTYLDKYLLGSMCQLAIVCAWHSIVAKID-----SKHD-AKVAELVFLTALAVIYIGFNAGICFHIYAFACKRRRIMKQKDREYMESV 382          
BLAST of Neur_chan_LBD domain-containing protein vs. TrEMBL
Match: A0A1S3HLY8 (uncharacterized protein LOC106156405 isoform X4 OS=Lingula unguis OX=7574 GN=LOC106156405 PE=3 SV=1)

HSP 1 Score: 357.451 bits (916), Expect = 3.674e-116
Identity = 185/334 (55.39%), Postives = 247/334 (73.95%), Query Frame = 3
Query:  246 KRQVYVCVVFLKIGEIDTIKEQYAADILIKCKWREPRLDH---NTEKL----EYDWANSWTPKLYIENTIGEAKEHVYQMIIFNENQHAFLCEKRRVSGIFLENLELNHFPFDVQDLTITIASNLPSTEIRLVNDPDETHRVNKQSFVDEQEWYLFKHIETEQKELAYEYADPSSVKPAISVKCRAARRPAYFIWNIFLVTFLICSLSLVTFAVDKSLPQNRLQXXXXXXXXXXXXXXXXNQCLPKISYLTYLDKYVISSLFILTVICVWHGMIVVIERFASKSEYDLPKDMEIYVIIGMAVAFAGYNFGFIVMIYAVACKRRRIMKQRDKEYL 1226
            K  V VCV+FLK+GEIDT+KEQ++AD+L+K KWREP LD    N ++L    E D+   W PKL++ENT+G+ KE  ++ + F+    AF+CE +R+ G F+ENLELN FPFDVQDLT+T+ S  P++E+ L+ D  E HRV KQSF+DEQEW L+KH+E+E K LA  + DPS  +  +SVKCRAARRP +F+WNIFLVTFL CSLS  TF+V+ +LPQNRLQL+FTLVLT VAFKFV+NQ LP++SYLTYLDKY++ S+  L ++C WH ++  I+     S++D  K  E+  +  +AV + G+N G    IYA ACKRRRIMKQ+D+EY+
Sbjct:    3 KVTVEVCVIFLKLGEIDTLKEQFSADVLVKAKWREPELDRKGKNKDELIDEDEIDFEKYWNPKLFVENTVGDPKEVRWRTLAFSSEGDAFICENQRLKGTFVENLELNDFPFDVQDLTVTVTSERPASELNLIEDRMELHRVYKQSFIDEQEWSLYKHLESESKFLAEPHGDPSVKRVLLSVKCRAARRPWFFVWNIFLVTFLFCSLSFATFSVEYNLPQNRLQLSFTLVLTAVAFKFVINQSLPRVSYLTYLDKYLLGSMCQLAIVCAWHSIVAKID-----SKHDA-KVAELVFLTALAVIYIGFNAGICFHIYAFACKRRRIMKQKDREYM 330          
BLAST of Neur_chan_LBD domain-containing protein vs. TrEMBL
Match: A0A1S3HPY9 (uncharacterized protein LOC106156405 isoform X3 OS=Lingula unguis OX=7574 GN=LOC106156405 PE=3 SV=1)

HSP 1 Score: 357.836 bits (917), Expect = 1.097e-115
Identity = 185/334 (55.39%), Postives = 247/334 (73.95%), Query Frame = 3
Query:  246 KRQVYVCVVFLKIGEIDTIKEQYAADILIKCKWREPRLDH---NTEKL----EYDWANSWTPKLYIENTIGEAKEHVYQMIIFNENQHAFLCEKRRVSGIFLENLELNHFPFDVQDLTITIASNLPSTEIRLVNDPDETHRVNKQSFVDEQEWYLFKHIETEQKELAYEYADPSSVKPAISVKCRAARRPAYFIWNIFLVTFLICSLSLVTFAVDKSLPQNRLQXXXXXXXXXXXXXXXXNQCLPKISYLTYLDKYVISSLFILTVICVWHGMIVVIERFASKSEYDLPKDMEIYVIIGMAVAFAGYNFGFIVMIYAVACKRRRIMKQRDKEYL 1226
            K  V VCV+FLK+GEIDT+KEQ++AD+L+K KWREP LD    N ++L    E D+   W PKL++ENT+G+ KE  ++ + F+    AF+CE +R+ G F+ENLELN FPFDVQDLT+T+ S  P++E+ L+ D  E HRV KQSF+DEQEW L+KH+E+E K LA  + DPS  +  +SVKCRAARRP +F+WNIFLVTFL CSLS  TF+V+ +LPQNRLQL+FTLVLT VAFKFV+NQ LP++SYLTYLDKY++ S+  L ++C WH ++  I+     S++D  K  E+  +  +AV + G+N G    IYA ACKRRRIMKQ+D+EY+
Sbjct:   48 KVTVEVCVIFLKLGEIDTLKEQFSADVLVKAKWREPELDRKGKNKDELIDEDEIDFEKYWNPKLFVENTVGDPKEVRWRTLAFSSEGDAFICENQRLKGTFVENLELNDFPFDVQDLTVTVTSERPASELNLIEDRMELHRVYKQSFIDEQEWSLYKHLESESKFLAEPHGDPSVKRVLLSVKCRAARRPWFFVWNIFLVTFLFCSLSFATFSVEYNLPQNRLQLSFTLVLTAVAFKFVINQSLPRVSYLTYLDKYLLGSMCQLAIVCAWHSIVAKID-----SKHDA-KVAELVFLTALAVIYIGFNAGICFHIYAFACKRRRIMKQKDREYM 375          
BLAST of Neur_chan_LBD domain-containing protein vs. TrEMBL
Match: A0A1S3HM64 (uncharacterized protein LOC106156405 isoform X1 OS=Lingula unguis OX=7574 GN=LOC106156405 PE=3 SV=1)

HSP 1 Score: 357.836 bits (917), Expect = 1.324e-115
Identity = 184/340 (54.12%), Postives = 250/340 (73.53%), Query Frame = 3
Query:  228 GDQNNRKRQVYVCVVFLKIGEIDTIKEQYAADILIKCKWREPRLDH---NTEKL----EYDWANSWTPKLYIENTIGEAKEHVYQMIIFNENQHAFLCEKRRVSGIFLENLELNHFPFDVQDLTITIASNLPSTEIRLVNDPDETHRVNKQSFVDEQEWYLFKHIETEQKELAYEYADPSSVKPAISVKCRAARRPAYFIWNIFLVTFLICSLSLVTFAVDKSLPQNRLQXXXXXXXXXXXXXXXXNQCLPKISYLTYLDKYVISSLFILTVICVWHGMIVVIERFASKSEYDLPKDMEIYVIIGMAVAFAGYNFGFIVMIYAVACKRRRIMKQRDKEYL 1226
             + ++ +  V VCV+FLK+GEIDT+KEQ++AD+L+K KWREP LD    N ++L    E D+   W PKL++ENT+G+ KE  ++ + F+    AF+CE +R+ G F+ENLELN FPFDVQDLT+T+ S  P++E+ L+ D  E HRV KQSF+DEQEW L+KH+E+E K LA  + DPS  +  +SVKCRAARRP +F+WNIFLVTFL CSLS  TF+V+ +LPQNRLQL+FTLVLT VAFKFV+NQ LP++SYLTYLDKY++ S+  L ++C WH ++  I+     S++D  K  E+  +  +AV + G+N G    IYA ACKRRRIMKQ+D+EY+
Sbjct:   46 AEPDHDRVTVEVCVIFLKLGEIDTLKEQFSADVLVKAKWREPELDRKGKNKDELIDEDEIDFEKYWNPKLFVENTVGDPKEVRWRTLAFSSEGDAFICENQRLKGTFVENLELNDFPFDVQDLTVTVTSERPASELNLIEDRMELHRVYKQSFIDEQEWSLYKHLESESKFLAEPHGDPSVKRVLLSVKCRAARRPWFFVWNIFLVTFLFCSLSFATFSVEYNLPQNRLQLSFTLVLTAVAFKFVINQSLPRVSYLTYLDKYLLGSMCQLAIVCAWHSIVAKID-----SKHDA-KVAELVFLTALAVIYIGFNAGICFHIYAFACKRRRIMKQKDREYM 379          
BLAST of Neur_chan_LBD domain-containing protein vs. Ensembl Cavefish
Match: glra2 (glycine receptor, alpha 2 [Source:ZFIN;Acc:ZDB-GENE-090407-1])

HSP 1 Score: 55.4546 bits (132), Expect = 6.069e-8
Identity = 64/271 (23.62%), Postives = 118/271 (43.54%), Query Frame = 3
Query:  261 VCVVFL-KIGEIDTIKEQYAADILIKCKWREPRL---DHNTEKLEYDWA---NSWTPKLYIENTIGEAKEHV-YQMIIFNENQHAFLCEKRRVSGIFLENLELNHFPFDVQDLTITIASNLPSTEIRLVNDPDETHRVNKQSFVDEQEWYLFKHIETEQKELAYEYADPSSVK-PAISVKCRAARRPAYFIWNIFLVTFLICSLSLVTFAVDKSLPQNRLQXXXXXXXXXXXXXXXXNQCLPKISYLTYLDKYV-ISSLFILTVICVWHGM 1043
             C +F+   G +      Y  +I ++ KW +PRL   ++    L+ D +   + W P L+  N  G     V     +   ++   +    R++ I    ++L +FP DVQ  T+ + S   +    +    DE      +         L + I  E+KEL Y     ++ K   I VK +  R+  Y++  +++ + LI  LS V+F ++      R+ L  T VLT+          LPK+SY+  +D ++ +  LF+   +  + G+
Sbjct:   62 TCNIFINSFGSVTETTMDYRVNIFLRQKWNDPRLAYSEYPDPSLDLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKDGTVLYSIRLTLILSCPMDLKNFPMDVQTCTMQLESFGYTMNDLIFEWLDEGPVQVAEGLT------LPQFIMREEKELGYCTKHYNTGKFTCIEVKFKLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLEYAGV 326          
BLAST of Neur_chan_LBD domain-containing protein vs. Ensembl Cavefish
Match: glra1 (glycine receptor alpha 1 [Source:NCBI gene;Acc:103026517])

HSP 1 Score: 51.9878 bits (123), Expect = 9.267e-7
Identity = 62/267 (23.22%), Postives = 120/267 (44.94%), Query Frame = 3
Query:  261 VCVVFL-KIGEIDTIKEQYAADILIKCKWREPRL---DHNTEKLEYDWA---NSWTPKLYIENTIGEAKEHVY---QMIIFNENQHAFLCEKRRVSGIFLENLELNHFPFDVQDLTITIASNLPSTEIRLVNDPDETHRVNKQSFVDEQEWYLFKHIETEQKELAYEYADPSSVK-PAISVKCRAARRPAYFIWNIFLVTFLICSLSLVTFAVDKSLPQNRLQXXXXXXXXXXXXXXXXNQCLPKISYLTYLDKYV-ISSLFILTVI 1025
             C +F+   G I      Y  +I ++ +W +PRL   ++  + L+ D +   + W P L+  N  G     V    +++  ++N +       R++ +    ++L +FP DVQ   + + S    T   L+ + DE   V     +      L + I  E+K+L Y     ++ K   I  +    R+  Y++  +++ + LI  LS V+F ++      R+ L  T VLT+          LPK+SY+  +D ++ +  LF+ + +
Sbjct:   80 TCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRISKNGNVLY--SIRITLVLACPMDLKNFPMDVQTCIMQLES-FGYTMNDLIFEWDEKGAVQVADGLT-----LPQFILKEEKDLRYCTKHYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSAL 338          
BLAST of Neur_chan_LBD domain-containing protein vs. Ensembl Cavefish
Match: glra1 (glycine receptor alpha 1 [Source:NCBI gene;Acc:103026517])

HSP 1 Score: 51.6026 bits (122), Expect = 1.018e-6
Identity = 62/267 (23.22%), Postives = 120/267 (44.94%), Query Frame = 3
Query:  261 VCVVFL-KIGEIDTIKEQYAADILIKCKWREPRL---DHNTEKLEYDWA---NSWTPKLYIENTIGEAKEHVY---QMIIFNENQHAFLCEKRRVSGIFLENLELNHFPFDVQDLTITIASNLPSTEIRLVNDPDETHRVNKQSFVDEQEWYLFKHIETEQKELAYEYADPSSVK-PAISVKCRAARRPAYFIWNIFLVTFLICSLSLVTFAVDKSLPQNRLQXXXXXXXXXXXXXXXXNQCLPKISYLTYLDKYV-ISSLFILTVI 1025
             C +F+   G I      Y  +I ++ +W +PRL   ++  + L+ D +   + W P L+  N  G     V    +++  ++N +       R++ +    ++L +FP DVQ   + + S    T   L+ + DE   V     +      L + I  E+K+L Y     ++ K   I  +    R+  Y++  +++ + LI  LS V+F ++      R+ L  T VLT+          LPK+SY+  +D ++ +  LF+ + +
Sbjct:   67 TCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRISKNGNVLY--SIRITLVLACPMDLKNFPMDVQTCIMQLES-FGYTMNDLIFEWDEKGAVQVADGLT-----LPQFILKEEKDLRYCTKHYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSAL 325          
BLAST of Neur_chan_LBD domain-containing protein vs. Ensembl Cavefish
Match: gabrg1 (gamma-aminobutyric acid type A receptor gamma1 subunit [Source:NCBI gene;Acc:103030074])

HSP 1 Score: 50.447 bits (119), Expect = 2.447e-6
Identity = 66/276 (23.91%), Postives = 107/276 (38.77%), Query Frame = 3
Query:  213 DERIFGDQNNRKRQVYVCVVFLKIGEIDTIKEQYAADILIKCKWREPRLDHNTEKLEYDWANSWTPKLYIENTIGEAKEHVYQMIIFNENQHAFLCEKRRVSGIFLEN------LELNHFPFDVQDLTITIAS-NLPSTEIRLVNDPDETHRVNKQSFVDEQEWYLFKHIETEQKELAYEYADPSSVKPAISVKCRAARRPAYFIWNIFLVTFLICSLSLVTFAVDKSLPQNRLQXXXXXXXXXXXXXXXXNQCLPKISYLTYLDKYVISSLFILT 1019
            D ++  D   +   +   V    IG +D I  +Y  DI     W + RL  N+        ++   K++I +T            I   N+   L    RV             L+L++FP D     +  +S   P  EI       + H    Q   D++ W L++      +         S     +S+    +RR  YF    ++   +I  LS V+F ++K     R  L  T VLT+     +  + LPK+SY+T +D +V S  FI T
Sbjct:   66 DNKLRPDIGVKPTLIDAAVYVNSIGPVDPINMEYTIDIFFAQSWYDSRLQFNSSMKVLMLNSNMVGKIWIPDTFFRNSRKSDAHWITTPNRLLRLWSNGRVMYTLRLTINAECYLKLHNFPMDEHSCPLEFSSYGYPKNEIEY-----KWHSRAVQ-VADQRYWRLYQFAFVGLQNTTGIAHTQSGDYVVMSILFTLSRRMGYFTIQTYIPCSMIVVLSWVSFWINKDAVPARTSLGITTVLTMTTLSTISRKSLPKVSYVTAMDLFV-SVCFIFT 334          
BLAST of Neur_chan_LBD domain-containing protein vs. Ensembl Cavefish
Match: GABRB2 (gamma-aminobutyric acid receptor subunit beta-2 [Source:NCBI gene;Acc:103038806])

HSP 1 Score: 49.2914 bits (116), Expect = 6.966e-6
Identity = 54/251 (21.51%), Postives = 106/251 (42.23%), Query Frame = 3
Query:  276 LKIGEIDTIKE---QYAADILIKCKWREPRLDHNTEKLEYDWANSWTPKLYIENT--IGEAKEHVYQMIIFNE----NQHAFLCEKRRVSGIFLENLELNHFPFDVQDLTITIASNLPSTEIRLVNDPDETHRVNKQSFVDEQEWYLFKHIETEQKELAYEYADPSSVKPAISVKCRAARRPAYFIWNIFLVTFLICSLSLVTFAVDKSLPQNRLQXXXXXXXXXXXXXXXXNQCLPKISYLTYLDKYVIS 1001
            + I  ID + E    Y   +  +  WR+ RL ++   L     N    +L++ +T  + + K  V+ + + N     +    +    R++      ++L  +P D Q+ T+ I S   +T+     D +   R    +    +   L +    + K ++      +   P +S+  +  R   YFI   ++ + LI  LS V+F ++      R+ L  T VLT+      + + LPKI Y+  +D Y++ 
Sbjct:   68 IDIASIDMVSEVNMDYTLTMYFQQAWRDKRLSYSEIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTD-----DIEFYWRGGNHAVTGVERIELPQFSIVDYKLISKNVVFSTGAYPRLSLSFKLKRNIGYFILQTYMPSILITILSWVSFWINYDASAARVALGITTVLTMTTINTHLRETLPKIPYVKAIDMYLMG 313          
BLAST of Neur_chan_LBD domain-containing protein vs. Ensembl Sea Lamprey
Match: glra4a (glycine receptor, alpha 4a [Source:ZFIN;Acc:ZDB-GENE-010410-3])

HSP 1 Score: 52.7582 bits (125), Expect = 8.895e-8
Identity = 66/294 (22.45%), Postives = 129/294 (43.88%), Query Frame = 3
Query:  264 CVVFLK-IGEIDTIKEQYAADILIKCKWREPRLDHNTEKLEY-----DWANS-----WTPKLYIENTIGEAKEHVYQMI-------IFNENQHAFLCEKRRVSGIFLENLELNHFPFDVQDLTITIASNLPSTEIRLVNDPDETHRVNKQSFVDEQEWYLFKHIETEQKELAYEYADPSSVKPAISVKCRAARRPAYFIWNIFLVTFLICSLSLVTFAVDKSLPQNRLQXXXXXXXXXXXXXXXXNQCLPKISYLTYLDKYVIS-SLFILTVICVWHGMIVVIERFA-SKSEYD 1085
            C + +K  G ++     Y+ +I ++  W +PR+ +  + +EY     D  NS     W P L+ EN    A + +YQ++        F      FLC   R+S +    + L  +P D Q  +I + S   +T   L+   ++T  V+  + V   ++ L       +    Y Y   S VK    +     R   Y++  +++ + L+  +S ++F ++      R+ L  T +LT+       N  LPK+SY+  +D ++ +  +F+ + +  +  + +   R   S S +D
Sbjct:   73 CSILVKGFGPVEEATMDYSINIFLRQTWNDPRILNVLKSIEYNTDFLDLGNSFVDSVWKPDLFFENEKSAAFQ-MYQLVTGFKYMYTFAMWITCFLC--FRLSLVLACPMSLEVYPMDAQYCSIYLESYGYTTN-DLIFQWNDTEPVSFGAGVSTPKFTLSNETFLGECTKEYTYGTFSCVKATFFLD----RDMGYYLIQVYIPSCLLVIISWLSFWLNVEAAPARVGLGITTILTVTTQMTSANAALPKVSYIKAIDVWMGACQVFVFSALLEFAAVNMATRRHGISPSHHD 358          
BLAST of Neur_chan_LBD domain-containing protein vs. Ensembl Sea Lamprey
Match: glra2 (glycine receptor, alpha 2 [Source:ZFIN;Acc:ZDB-GENE-090407-1])

HSP 1 Score: 46.2098 bits (108), Expect = 9.257e-6
Identity = 64/268 (23.88%), Postives = 116/268 (43.28%), Query Frame = 3
Query:  264 CVVFL-KIGEIDTIKEQYAADILIKCKWREPRL---DHNTEKLEYDWA---NSWTPKLYIENTIGEAKEHVYQ----MIIFNENQHAFLCEKRRVSGIFLENLELNHFPFDVQDLTITIASNLPSTEIRLVNDPDETHRVNKQSFVDEQEWY-LFKHIETEQKELAYEYADPSSVK-PAISVKCRAARRPAYFIWNIFLVTFLICSLSLVTFAVDKSLPQNRLQXXXXXXXXXXXXXXXXNQCLPKISYLTYLDKYV-ISSLFILTVI 1025
            C +F+   G I      Y  +I ++ +W +PRL   ++  + L+ D +   + W P L+  N  G     V      + IF +    +     R++      ++L +FP DVQ    T A  L S    +    D      ++  V   E   L + +  ++K+L Y     ++ K   I VK    R+  Y++  +++ + LI  LS V+F ++      R+ L  T VLT+          LPK+SY+  +D ++ +  LF+   +
Sbjct:   10 CNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKDGNVLY---SIRLTLTLSCPMDLKNFPMDVQ----TCAMQLESFGYTM---NDLIFEWKQEGAVQVAEGLTLPQFVLKDEKDLVYCTKHYNTGKFTCIEVKFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFAAL 267          
BLAST of Neur_chan_LBD domain-containing protein vs. Ensembl Nematostella
Match: EDO32790 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SU26])

HSP 1 Score: 127.487 bits (319), Expect = 1.114e-32
Identity = 84/284 (29.58%), Postives = 148/284 (52.11%), Query Frame = 3
Query:  282 IGEIDTIKEQYAADILIKCKWREPRLDHNTEKLEYDWANSWTPKLYIENTIGEAKEHVYQMIIFNENQHAFLC-EKRRVSGIFLENLELNHFPFDVQDLTITIASNLPSTEIRLVNDPDETHRVNKQSFVDEQEWYLFKHIETEQKELAYEYADPSSVK-PAISVKCRAARRPAYFIWNIFLVTFLICSLSLVTFAVDKSLPQNRLQXXXXXXXXXXXXXXXXNQCLPKISYLTYLDKYVISSLFILTVICVWHGMIVVIERFASKSEYD---LPKDMEIYVII 1118
            +G+ID I++Q+  ++ +   WREP+L     + E  W N W+PK+   N++   + +  + + + EN    L  E  ++ G F E   L  FP D+Q+L+I I+S+     +    D  +   + +Q+F   ++W L+ H+ T+      E   P+    P   +     RR  ++ WN  +V  ++ +LS  +FA+      +RL +T  L+L  VA+KFV +  LP+ SYLT+LDKY + +L  ++ I V + + V +E   S+  YD   L   + +YVI+
Sbjct:   27 LGDIDVIRQQFTCELWMTASWREPKLAGKKNE-EVKWDNEWSPKISFSNSLLLDRVYKGRRLYYEENSTVPLAQEVYKIRGTFKEQFSLEQFPVDLQELSIIISSDWSDRTVTFEKDMAKPDYLRQQTFSSPRDWVLYPHVHTDTATQEGEGLGPNDRSYPVYIITAHVRRRAVHYFWNTAVVMSVLTALSFASFAIPPQQTADRLTVTLLLLLISVAYKFVTSLHLPRTSYLTFLDKYQLGNLLFISFIAVLNTIAVAVE---SRDTYDMVCLYAGLALYVIL 306          
BLAST of Neur_chan_LBD domain-containing protein vs. Ensembl Nematostella
Match: EDO26859 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7TAV8])

HSP 1 Score: 66.6254 bits (161), Expect = 5.877e-13
Identity = 50/161 (31.06%), Postives = 86/161 (53.42%), Query Frame = 3
Query:  648 VNKQSFVDEQEWYLFKHIETEQKELAYEYADPSSVK-PAISVKCRAARRPAYFIWNIFLVTFLICSLSLVTFAVDKSLPQNRLQXXXXXXXXXXXXXXXXNQCLPKISYLTYLDKYVISSLFILTVICVWHGMIVVIERFASKSEYD---LPKDMEIYVII 1118
            + +Q+F   ++W L+ H+ T+      E   P+    P   +     RR  ++ WN  +V  ++ +LS  +FA+      +RL +T  L+L  VA+KFV +  LP+ SYLT+LDKY + +L  ++ I V + + V +E   S+  YD   L   + +YVI+
Sbjct:    7 LRQQTFSSPRDWVLYPHVHTDTATQEGEGLGPNDRSYPVYIITAHVRRRAVHYFWNTAVVMSVLTALSFASFAIPPQQTADRLTVTLLLLLISVAYKFVTSLHLPRTSYLTFLDKYQLGNLLFISFIAVLNTIAVAVE---SRDTYDMVCLYAGLALYVIL 164          
BLAST of Neur_chan_LBD domain-containing protein vs. Ensembl Nematostella
Match: EDO37555 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SFG6])

HSP 1 Score: 65.0846 bits (157), Expect = 1.990e-11
Identity = 77/288 (26.74%), Postives = 120/288 (41.67%), Query Frame = 3
Query:  192 DNYSVNNDERIFGDQNNRKRQVYVCVVFLKIGEIDTIKEQYAADILIKCKWREPRLDH---NTEKLEYDWANS-WTPKLYIENTIGEAKEHVYQMI--IFNENQHAFLCEKRRVSGIFLENLELNHFPFDVQDLTITIAS---NLPSTEIRLVNDPDETHRVNKQSFVDEQEWYLFKHIETEQKELAYEYADPSSVKPAISVKCRAARRPAYFIWNIFLVTFLICSLSLVTFAVDKSLPQNRLQXXXXXXXXXXXXXXXXNQCLPKISYLTYLDKYVISS-LFILTVI 1025
            DN     D R+  D       V V    L I  I+ I   Y  D  ++  WR+PRL H   +T  L     +  W P  Y  N+   +K H    I  + + +    +    RV+      + L  FP DVQ+  I I S   +  + + +  N  D    VNK+  + +   Y    I   +    Y   + S     ++   R  RR  YFI +I+    LI  LS ++F +       R+ L  T VLT+     ++N  +PK+SY+  +D Y+I   LF+  V+
Sbjct:   11 DNLIQGYDPRLRPDFGGDPVTVTVGFWVLSIDAINVIDMDYRMDFFLRQLWRDPRLKHRFDDTLALSNTMLDKIWVPDTYFVNS-KMSKFHSVTTINKMLSISPDGLVHYNSRVTVKASCAMNLRMFPKDVQNCNIDIESYGYSADNVQYQWENRSDNGIAVNKK--IRDMPQYNLSDINVSRHFTMYVAGNWS----GLTATFRFRRRSGYFIIHIYAPCALIVILSWISFCIPPESTAARIALGITSVLTITTILNMLNNSMPKVSYVKAVDWYLIGCFLFVFAVL 291          
BLAST of Neur_chan_LBD domain-containing protein vs. Ensembl Nematostella
Match: EDO41538 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S448])

HSP 1 Score: 59.6918 bits (143), Expect = 9.529e-10
Identity = 66/250 (26.40%), Postives = 108/250 (43.20%), Query Frame = 3
Query:  300 IKEQYAADILIKCKWREPRLDHNTEKLEYDWANS----WTPKLYIENTIGEAKEHVYQMIIFNENQH------AFLCEKRRVSGIFLENLELNHFPFDVQDLTITIASNLPSTEIRLVNDPDETHRVNKQSFVDEQEWYLFKHIETEQKELAYEYADPSSVKPAISVKCRAARRPAYFIWNIFLVTFLICSLSLVTFAVDKSLPQNRLQXXXXXXXXXXXXXXXXNQCLPKISYLTYLDKY-VISSLFIL 1016
            + + Y+ DI  +  WR+ RL H+  K+    AN     WTP  Y  N       HV +     EN          +    R++      ++L  FP D QD  + I S   + E  + N     +R      +   E   F   E   + +   ++  +    ++ V  R  RR +YFI   ++ +  I  LS + F ++K+    R+ LT T +L+ +     +N  LP+ISYL  +D Y +IS +FIL
Sbjct:    1 MHQDYSLDIFFRQWWRDERLAHDVNKVFNMAANPGQYFWTPDTYFVNVKSSKFHHVTR-----ENMRTKIWPDGLIYYSSRITLTASCEMDLRFFPMDTQDCVLKIESYAYTVEDVIYN---WNNRGTTPIEIFAGEMAQFDMTEMTMQTMI-TFSLLTGSFDSLRVSFRFKRRTSYFIVQHYVPSAFIVFLSWLGFWINKNAVPARISLTVTCILSTMVLFESINSSLPRISYLKAVDYYLIISFMFIL 241          
BLAST of Neur_chan_LBD domain-containing protein vs. Ensembl Nematostella
Match: EDO43149 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RZH4])

HSP 1 Score: 55.0694 bits (131), Expect = 1.539e-8
Identity = 62/256 (24.22%), Postives = 110/256 (42.97%), Query Frame = 3
Query:  276 LKIGEIDTIKEQYAADILIKCKWREPRLDHNTEKLEYDWANS----WTPKLYIENTIGEAKEHVY----QMIIFNENQHAFLCEKRRVSGIFLENLELNHFPFDVQDLTITIASNLPSTEIRLVNDPDETHRVNKQSFVD----EQEWYLFKHIETEQKELAYEYADPSSVKPAISVKCRAARRPAYFIWNIFLVTFLICSLSLVTFAVDKSLPQNRLQXXXXXXXXXXXXXXXXNQCLPKISYLTYLDKYVISSL 1007
            + IGEI   +  Y+ DI  +  W +PR  HN  K     A++    WTP  Y  N +  AK H        ++ N +   +   +  ++     +++L  +P D+Q   + I S   +      +D D T +      V+    E   + F    T  K         +S++   + K    RR AYFI   ++   ++  LS  TF + ++    R+ L+ T +LT +      N  +PK+SY   +D ++++SL
Sbjct:   13 VSIGEIKEAEMVYSMDIFFRQWWYDPRFAHNFSKPFTMAADATQLFWTPDTYFWN-VKNAKYHRVTRENMRVMINPDGKIYFSTRITITA--QCDMDLRLYPMDIQYCPLIIESYAHTR-----SDVDYTWKGGDDQGVEIVSKEMAQFEFIGANTYTKAQTNSKGSFASLRAEFTFK----RRVAYFITATYMPAMILVILSWCTFWIHRNAVPARVTLSITTILTTILLTSSTNGSMPKVSYSKAIDYFLMTSL 256          
BLAST of Neur_chan_LBD domain-containing protein vs. Ensembl Medaka
Match: glra2 (glycine receptor alpha 2 [Source:NCBI gene;Acc:101169154])

HSP 1 Score: 56.6102 bits (135), Expect = 2.464e-8
Identity = 70/274 (25.55%), Postives = 120/274 (43.80%), Query Frame = 3
Query:  261 VCVVFL-KIGEIDTIKEQYAADILIKCKWREPRLDHNT---EKLEYDWA---NSWTPKLYIENTIGEAKEHVYQ----MIIFNENQHAFLCEKRRVSGIFLENLELNHFPFDVQDLTITIASNLPSTEIRLVNDPDETHRVNKQSFVDEQEWYLFKHIETEQKELAYEYADPSSVK-PAISVKCRAARRPAYFIWNIFLVTFLICSLSLVTFAVDKSLPQNRLQXXXXXXXXXXXXXXXXNQCLPKISYLTYLDKYV-ISSLFILTVICVWHGM 1043
             C +F+   G I      Y  +I ++ KW +PRL ++      L+ D +   + W P L+  N  G     V      + IF +    +     R++ I    ++L +FP DVQ  T+ + S    T   LV +  E   V        +   L + I  E+KEL Y     ++ K   I VK    R+  Y++  +++ + LI  LS V+F ++      R+ L  T VLT+          LPK+SY+  +D ++ +  LF+   +  + G+
Sbjct:   75 TCNIFINSFGSIAETTMDYRVNIFLRQKWNDPRLAYSKYPDSSLDLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRIFKDGTVLY---SIRLTLILSCPMDLKNFPMDVQTCTMQLES-FGYTMNDLVFEWLEYGAVQV-----SEGLTLPQFIMKEEKELGYCTKHYNTGKFTCIEVKFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLEYAGV 339          
BLAST of Neur_chan_LBD domain-containing protein vs. Ensembl Medaka
Match: glra1 (glycine receptor alpha 1 [Source:NCBI gene;Acc:101173557])

HSP 1 Score: 51.9878 bits (123), Expect = 7.508e-7
Identity = 63/267 (23.60%), Postives = 120/267 (44.94%), Query Frame = 3
Query:  261 VCVVFL-KIGEIDTIKEQYAADILIKCKWREPRL---DHNTEKLEYDWA---NSWTPKLYIENTIGEAKEHVY---QMIIFNENQHAFLCEKRRVSGIFLENLELNHFPFDVQDLTITIASNLPSTEIRLVNDPDETHRVNKQSFVDEQEWYLFKHIETEQKELAYEYADPSSVK-PAISVKCRAARRPAYFIWNIFLVTFLICSLSLVTFAVDKSLPQNRLQXXXXXXXXXXXXXXXXNQCLPKISYLTYLDKYV-ISSLFILTVI 1025
             C +F+   G I      Y  +I ++ +W +PRL   ++  + L+ D +   + W P L+  N  G     V    +++  ++N +       R++ I    ++L +FP DVQ   + + S    T   L+ + DE   V     +      L + I  E+K+L Y     ++ K   I  +    R+  Y++  +++ + LI  LS V+F ++      R+ L  T VLT+          LPK+SY+  +D ++ +  LF+ + +
Sbjct:   85 TCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRISKNGNVLY--SIRITLILACPMDLKNFPMDVQTCIMQLES-FGYTMNDLIFEWDEKGAVQVADGLT-----LPQFILKEEKDLRYCTKHYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSAL 343          
BLAST of Neur_chan_LBD domain-containing protein vs. Ensembl Medaka
Match: glra1 (glycine receptor alpha 1 [Source:NCBI gene;Acc:101173557])

HSP 1 Score: 51.9878 bits (123), Expect = 7.562e-7
Identity = 63/267 (23.60%), Postives = 120/267 (44.94%), Query Frame = 3
Query:  261 VCVVFL-KIGEIDTIKEQYAADILIKCKWREPRL---DHNTEKLEYDWA---NSWTPKLYIENTIGEAKEHVY---QMIIFNENQHAFLCEKRRVSGIFLENLELNHFPFDVQDLTITIASNLPSTEIRLVNDPDETHRVNKQSFVDEQEWYLFKHIETEQKELAYEYADPSSVK-PAISVKCRAARRPAYFIWNIFLVTFLICSLSLVTFAVDKSLPQNRLQXXXXXXXXXXXXXXXXNQCLPKISYLTYLDKYV-ISSLFILTVI 1025
             C +F+   G I      Y  +I ++ +W +PRL   ++  + L+ D +   + W P L+  N  G     V    +++  ++N +       R++ I    ++L +FP DVQ   + + S    T   L+ + DE   V     +      L + I  E+K+L Y     ++ K   I  +    R+  Y++  +++ + LI  LS V+F ++      R+ L  T VLT+          LPK+SY+  +D ++ +  LF+ + +
Sbjct:   57 TCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRISKNGNVLY--SIRITLILACPMDLKNFPMDVQTCIMQLES-FGYTMNDLIFEWDEKGAVQVADGLT-----LPQFILKEEKDLRYCTKHYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSAL 315          
BLAST of Neur_chan_LBD domain-containing protein vs. Ensembl Medaka
Match: glra1 (glycine receptor alpha 1 [Source:NCBI gene;Acc:101173557])

HSP 1 Score: 51.9878 bits (123), Expect = 9.053e-7
Identity = 63/267 (23.60%), Postives = 120/267 (44.94%), Query Frame = 3
Query:  261 VCVVFL-KIGEIDTIKEQYAADILIKCKWREPRL---DHNTEKLEYDWA---NSWTPKLYIENTIGEAKEHVY---QMIIFNENQHAFLCEKRRVSGIFLENLELNHFPFDVQDLTITIASNLPSTEIRLVNDPDETHRVNKQSFVDEQEWYLFKHIETEQKELAYEYADPSSVK-PAISVKCRAARRPAYFIWNIFLVTFLICSLSLVTFAVDKSLPQNRLQXXXXXXXXXXXXXXXXNQCLPKISYLTYLDKYV-ISSLFILTVI 1025
             C +F+   G I      Y  +I ++ +W +PRL   ++  + L+ D +   + W P L+  N  G     V    +++  ++N +       R++ I    ++L +FP DVQ   + + S    T   L+ + DE   V     +      L + I  E+K+L Y     ++ K   I  +    R+  Y++  +++ + LI  LS V+F ++      R+ L  T VLT+          LPK+SY+  +D ++ +  LF+ + +
Sbjct:   70 TCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRISKNGNVLY--SIRITLILACPMDLKNFPMDVQTCIMQLES-FGYTMNDLIFEWDEKGAVQVADGLT-----LPQFILKEEKDLRYCTKHYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSAL 328          
BLAST of Neur_chan_LBD domain-containing protein vs. Ensembl Medaka
Match: gabrg1 (gamma-aminobutyric acid type A receptor gamma1 subunit [Source:NCBI gene;Acc:101155813])

HSP 1 Score: 51.2174 bits (121), Expect = 1.428e-6
Identity = 65/278 (23.38%), Postives = 110/278 (39.57%), Query Frame = 3
Query:  213 DERIFGDQNNRKRQVYVCVVFLKIGEIDTIKEQYAADILIKCKWREPRLDHNTEKLEYDWANSWTPKLYIENTIGEAKEHVYQMIIFNENQHAFLCEKRRVSGIFLEN------LELNHFPFDVQDLTITIAS-NLPSTEIRLVNDPDETHRVNKQSF--VDEQEWYLFKHIETEQKELAYEYADPSSVKPAISVKCRAARRPAYFIWNIFLVTFLICSLSLVTFAVDKSLPQNRLQXXXXXXXXXXXXXXXXNQCLPKISYLTYLDKYVISSLFILT 1019
            D ++  D   R   +   V    IG +D I  +Y  DI     W + RL  N+        ++   K++I +T            I   N+   L    RV             L+L++FP D     +  +S   P  EI         +R  +++    D++ W L++      +  +      S     +++    +RR  YF    ++   +I  LS V+F ++K     R  L  T VLT+     +  + LPK+SY+T +D +V S  FI T
Sbjct:   65 DNKLRPDIGVRPTVIETAVYVNSIGPVDPINMEYTIDIFFAQTWYDSRLKFNSSMKLLMLNSNMVGKIWIPDTFFRNSRKSDAHWITTPNRLLRLWSNGRVMYTLRLTINAECYLKLHNFPMDEHSCPLEFSSYGYPRNEI--------MYRWQRRAVEVADQRYWRLYQFAFVGMRNTSDVAHTQSGEYVIMTIFFDLSRRMGYFTIQTYIPCSMIVVLSWVSFWINKDAVPARTSLGITTVLTMTTLSTISRKSLPKVSYITAMDLFV-SVCFIFT 333          
BLAST of Neur_chan_LBD domain-containing protein vs. Planmine SMEST
Match: SMESG000021796.1 (SMESG000021796.1)

HSP 1 Score: 852.047 bits (2200), Expect = 0.000e+0
Identity = 425/425 (100.00%), Postives = 425/425 (100.00%), Query Frame = 3
Query:   60 MFSSPLININGLTQNSSPPETVFSPSDDAAMPLIDVRNRYKHESDNYSVNNDERIFGDQNNRKRQVYVCVVFLKIGEIDTIKEQYAADILIKCKWREPRLDHNTEKLEYDWANSWTPKLYIENTIGEAKEHVYQMIIFNENQHAFLCEKRRVSGIFLENLELNHFPFDVQDLTITIASNLPSTEIRLVNDPDETHRVNKQSFVDEQEWYLFKHIETEQKELAYEYADPSSVKPAISVKCRAARRPAYFIWNIFLVTFLICSLSLVTFAVDKSLPQNRLQXXXXXXXXXXXXXXXXNQCLPKISYLTYLDKYVISSLFILTVICVWHGMIVVIERFASKSEYDLPKDMEIYVIIGMAVAFAGYNFGFIVMIYAVACKRRRIMKQRDKEYLERLQCQLKYKGARTIKMIQQTHQMHEVKENRRGTFL 1334
            MFSSPLININGLTQNSSPPETVFSPSDDAAMPLIDVRNRYKHESDNYSVNNDERIFGDQNNRKRQVYVCVVFLKIGEIDTIKEQYAADILIKCKWREPRLDHNTEKLEYDWANSWTPKLYIENTIGEAKEHVYQMIIFNENQHAFLCEKRRVSGIFLENLELNHFPFDVQDLTITIASNLPSTEIRLVNDPDETHRVNKQSFVDEQEWYLFKHIETEQKELAYEYADPSSVKPAISVKCRAARRPAYFIWNIFLVTFLICSLSLVTFAVDKSLPQNRLQLTFTLVLTLVAFKFVVNQCLPKISYLTYLDKYVISSLFILTVICVWHGMIVVIERFASKSEYDLPKDMEIYVIIGMAVAFAGYNFGFIVMIYAVACKRRRIMKQRDKEYLERLQCQLKYKGARTIKMIQQTHQMHEVKENRRGTFL
Sbjct:    1 MFSSPLININGLTQNSSPPETVFSPSDDAAMPLIDVRNRYKHESDNYSVNNDERIFGDQNNRKRQVYVCVVFLKIGEIDTIKEQYAADILIKCKWREPRLDHNTEKLEYDWANSWTPKLYIENTIGEAKEHVYQMIIFNENQHAFLCEKRRVSGIFLENLELNHFPFDVQDLTITIASNLPSTEIRLVNDPDETHRVNKQSFVDEQEWYLFKHIETEQKELAYEYADPSSVKPAISVKCRAARRPAYFIWNIFLVTFLICSLSLVTFAVDKSLPQNRLQLTFTLVLTLVAFKFVVNQCLPKISYLTYLDKYVISSLFILTVICVWHGMIVVIERFASKSEYDLPKDMEIYVIIGMAVAFAGYNFGFIVMIYAVACKRRRIMKQRDKEYLERLQCQLKYKGARTIKMIQQTHQMHEVKENRRGTFL 425          
BLAST of Neur_chan_LBD domain-containing protein vs. Planmine SMEST
Match: SMESG000066647.1 (SMESG000066647.1)

HSP 1 Score: 617.846 bits (1592), Expect = 0.000e+0
Identity = 309/404 (76.49%), Postives = 351/404 (86.88%), Query Frame = 3
Query:  141 DAAMPLID-VRNR-----YKHESDNYSVNNDERIFGDQNNRKRQVYVCVVFLKIGEIDTIKEQYAADILIKCKWREPRLDHNTEKLEYDWANSWTPKLYIENTIGEAKEHVYQMIIFNENQHAFLCEKRRVSGIFLENLELNHFPFDVQDLTITIASNLPSTEIRLVNDPDETHRVNKQSFVDEQEWYLFKHIETEQKELAYEYADPSSVKPAISVKCRAARRPAYFIWNIFLVTFLICSLSLVTFAVDKSLPQNRLQXXXXXXXXXXXXXXXXNQCLPKISYLTYLDKYVISSLFILTVICVWHGMIVVIERFASKSEYDLPKDMEIYVIIGMAVAFAGYNFGFIVMIYAVACKRRRIMKQRDKEYLERLQCQLKYKGARTIKMIQQTHQMHEVKENRRGTFL 1334
            +AA P++  +R R      K  S NY + N       ++N K QVYVCVVFLKIGEIDTIKEQYAAD+LIK KWREP LD+ TE L+YDWANSW+PKLYIENTIGEAKEHVY MI FNE  HAFLCEKRRVSG+FLENLELNHFPFDVQDLTIT+ASNLP++EIRLVNDPDETHR+NKQSFVDEQEWYL+KHIETEQ+ELAYEY D ++V+PA+SVKCRAARRPAYFIWNIFLVTFLICSLSLVTFAVDK LPQNRLQLT+TLVLTLVAFKFVVNQCLPKISYLTYLDKYVISSLFILT+IC+WHG+IVVIE+ + + +Y +P DME+YVII MA+ + GYN  FIVMIY VACKRRR M QRDKEY+E++QCQ+KYKG R ++MIQQTHQ+HEVKEN   TF+
Sbjct:  189 EAAYPMMSGIRTRRGAVTSKETSSNYRLYN----IVQKDNVKHQVYVCVVFLKIGEIDTIKEQYAADVLIKSKWREPMLDNQTETLKYDWANSWSPKLYIENTIGEAKEHVYHMITFNEFNHAFLCEKRRVSGVFLENLELNHFPFDVQDLTITVASNLPTSEIRLVNDPDETHRINKQSFVDEQEWYLYKHIETEQRELAYEYTDLATVRPALSVKCRAARRPAYFIWNIFLVTFLICSLSLVTFAVDKKLPQNRLQLTYTLVLTLVAFKFVVNQCLPKISYLTYLDKYVISSLFILTLICLWHGLIVVIEKVSDRFKYVIPDDMEVYVIIFMAIGYMGYNIAFIVMIYCVACKRRRDMMQRDKEYVEKVQCQMKYKGMRAMRMIQQTHQLHEVKENGNATFI 588          
BLAST of Neur_chan_LBD domain-containing protein vs. Planmine SMEST
Match: SMESG000066647.1 (SMESG000066647.1)

HSP 1 Score: 613.224 bits (1580), Expect = 0.000e+0
Identity = 315/459 (68.63%), Postives = 365/459 (79.52%), Query Frame = 3
Query:   66 SSPL-ININGLTQNSSPPETVFSPSDDAAMPLIDV-----RNRYKHESDNYSVNNDER-------IFGDQNNR-----------------------KRQVYVCVVFLKIGEIDTIKEQYAADILIKCKWREPRLDHNTEKLEYDWANSWTPKLYIENTIGEAKEHVYQMIIFNENQHAFLCEKRRVSGIFLENLELNHFPFDVQDLTITIASNLPSTEIRLVNDPDETHRVNKQSFVDEQEWYLFKHIETEQKELAYEYADPSSVKPAISVKCRAARRPAYFIWNIFLVTFLICSLSLVTFAVDKSLPQNRLQXXXXXXXXXXXXXXXXNQCLPKISYLTYLDKYVISSLFILTVICVWHGMIVVIERFASKSEYDLPKDMEIYVIIGMAVAFAGYNFGFIVMIYAVACKRRRIMKQRDKEYLERLQCQLKYKGARTIKMIQQTHQMHEVKENRRGTFL 1334
            SSPL +    ++     P + F P+D+     +D+     RN    +S++   N+++R       +F   N R                       K QVYVCVVFLKIGEIDTIKEQYAAD+LIK KWREP LD+ TE L+YDWANSW+PKLYIENTIGEAKEHVY MI FNE  HAFLCEKRRVSG+FLENLELNHFPFDVQDLTIT+ASNLP++EIRLVNDPDETHR+NKQSFVDEQEWYL+KHIETEQ+ELAYEY D ++V+PA+SVKCRAARRPAYFIWNIFLVTFLICSLSLVTFAVDK LPQNRLQLT+TLVLTLVAFKFVVNQCLPKISYLTYLDKYVISSLFILT+IC+WHG+IVVIE+ + + +Y +P DME+YVII MA+ + GYN  FIVMIY VACKRRR M QRDKEY+E++QCQ+KYKG R ++MIQQTHQ+HEVKEN   TF+
Sbjct:   11 SSPLHLQPESISHQPFLPASGFLPNDEDEDTRLDIEFESIRNASYTKSESTKSNDNDRASIINETLFNHANKRIRMKSFNKFHRLDSKCLNVDTSIKHQVYVCVVFLKIGEIDTIKEQYAADVLIKSKWREPMLDNQTETLKYDWANSWSPKLYIENTIGEAKEHVYHMITFNEFNHAFLCEKRRVSGVFLENLELNHFPFDVQDLTITVASNLPTSEIRLVNDPDETHRINKQSFVDEQEWYLYKHIETEQRELAYEYTDLATVRPALSVKCRAARRPAYFIWNIFLVTFLICSLSLVTFAVDKKLPQNRLQLTYTLVLTLVAFKFVVNQCLPKISYLTYLDKYVISSLFILTLICLWHGLIVVIEKVSDRFKYVIPDDMEVYVIIFMAIGYMGYNIAFIVMIYCVACKRRRDMMQRDKEYVEKVQCQMKYKGMRAMRMIQQTHQLHEVKENGNATFI 469          
BLAST of Neur_chan_LBD domain-containing protein vs. Planmine SMEST
Match: SMESG000039749.1 (SMESG000039749.1)

HSP 1 Score: 534.643 bits (1376), Expect = 0.000e+0
Identity = 256/369 (69.38%), Postives = 314/369 (85.09%), Query Frame = 3
Query:  228 GDQNNRKRQVYVCVVFLKIGEIDTIKEQYAADILIKCKWREPRLDHNTEKLEYDWANSWTPKLYIENTIGEAKEHVYQMIIFNENQHAFLCEKRRVSGIFLENLELNHFPFDVQDLTITIASNLPSTEIRLVNDPDETHRVNKQSFVDEQEWYLFKHIETEQKELAYEYADPSSVKPAISVKCRAARRPAYFIWNIFLVTFLICSLSLVTFAVDKSLPQNRLQXXXXXXXXXXXXXXXXNQCLPKISYLTYLDKYVISSLFILTVICVWHGMIVVIERFASKSEYDLPKDMEIYVIIGMAVAFAGYNFGFIVMIYAVACKRRRIMKQRDKEYLERLQCQLKYKGARTIKMIQQTHQMHEVKENRRGTFL 1334
            GD   +KRQVY+CVVFLKIGEIDTIKEQ+ ADI++K KWREP LD + + L YDW+  WTPKLY+ENT+G+ +EHVYQMI FNE  HAFLCEKRRVSG+FLENLELNHFPFDVQDLTI +A+ L S+EIRLVNDPDE HR+NKQSFVDEQEW+L+K+IE+EQK++ +EYADP SV+PA+ V+CRAARRPAYF+WN+FLVTFLICSLSLVTFAVDK LPQNRLQL++TLVLTL+AFKFVVNQCLPKISYLTYLDKY+IS+LF LT++C WHG++VVI R   +    L +++E+YV+I ++V +  YN GF+++IY VA KRRR M++ DKEYLE++QCQ+K KG R  +M QQT Q+HEVK N    F+
Sbjct:   69 GDDTLKKRQVYICVVFLKIGEIDTIKEQFTADIIVKAKWREPSLDFHIDGLNYDWSKCWTPKLYVENTVGDPREHVYQMITFNEFGHAFLCEKRRVSGVFLENLELNHFPFDVQDLTIIVATTLSSSEIRLVNDPDEPHRINKQSFVDEQEWFLYKNIESEQKDMIFEYADPLSVRPALLVQCRAARRPAYFLWNLFLVTFLICSLSLVTFAVDKDLPQNRLQLSYTLVLTLIAFKFVVNQCLPKISYLTYLDKYIISNLFFLTLVCAWHGLVVVINRIIKRVNKSLSENLELYVLISISVGYGLYNLGFVLVIYLVAFKRRRQMQKLDKEYLEKVQCQIKTKGNRRARMNQQTRQIHEVKANGSTVFI 437          
BLAST of Neur_chan_LBD domain-containing protein vs. Planmine SMEST
Match: SMESG000039749.1 (SMESG000039749.1)

HSP 1 Score: 534.643 bits (1376), Expect = 0.000e+0
Identity = 256/369 (69.38%), Postives = 314/369 (85.09%), Query Frame = 3
Query:  228 GDQNNRKRQVYVCVVFLKIGEIDTIKEQYAADILIKCKWREPRLDHNTEKLEYDWANSWTPKLYIENTIGEAKEHVYQMIIFNENQHAFLCEKRRVSGIFLENLELNHFPFDVQDLTITIASNLPSTEIRLVNDPDETHRVNKQSFVDEQEWYLFKHIETEQKELAYEYADPSSVKPAISVKCRAARRPAYFIWNIFLVTFLICSLSLVTFAVDKSLPQNRLQXXXXXXXXXXXXXXXXNQCLPKISYLTYLDKYVISSLFILTVICVWHGMIVVIERFASKSEYDLPKDMEIYVIIGMAVAFAGYNFGFIVMIYAVACKRRRIMKQRDKEYLERLQCQLKYKGARTIKMIQQTHQMHEVKENRRGTFL 1334
            GD   +KRQVY+CVVFLKIGEIDTIKEQ+ ADI++K KWREP LD + + L YDW+  WTPKLY+ENT+G+ +EHVYQMI FNE  HAFLCEKRRVSG+FLENLELNHFPFDVQDLTI +A+ L S+EIRLVNDPDE HR+NKQSFVDEQEW+L+K+IE+EQK++ +EYADP SV+PA+ V+CRAARRPAYF+WN+FLVTFLICSLSLVTFAVDK LPQNRLQL++TLVLTL+AFKFVVNQCLPKISYLTYLDKY+IS+LF LT++C WHG++VVI R   +    L +++E+YV+I ++V +  YN GF+++IY VA KRRR M++ DKEYLE++QCQ+K KG R  +M QQT Q+HEVK N    F+
Sbjct:   67 GDDTLKKRQVYICVVFLKIGEIDTIKEQFTADIIVKAKWREPSLDFHIDGLNYDWSKCWTPKLYVENTVGDPREHVYQMITFNEFGHAFLCEKRRVSGVFLENLELNHFPFDVQDLTIIVATTLSSSEIRLVNDPDEPHRINKQSFVDEQEWFLYKNIESEQKDMIFEYADPLSVRPALLVQCRAARRPAYFLWNLFLVTFLICSLSLVTFAVDKDLPQNRLQLSYTLVLTLIAFKFVVNQCLPKISYLTYLDKYIISNLFFLTLVCAWHGLVVVINRIIKRVNKSLSENLELYVLISISVGYGLYNLGFVLVIYLVAFKRRRQMQKLDKEYLEKVQCQIKTKGNRRARMNQQTRQIHEVKANGSTVFI 435          
The following BLAST results are available for this feature:
BLAST of Neur_chan_LBD domain-containing protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
GABRB31.092e-622.57gamma-aminobutyric acid type A receptor beta3 subu... [more]
GABRB31.203e-622.57gamma-aminobutyric acid type A receptor beta3 subu... [more]
GABRB31.406e-622.57gamma-aminobutyric acid type A receptor beta3 subu... [more]
GABRB31.407e-622.57gamma-aminobutyric acid type A receptor beta3 subu... [more]
GLRA13.177e-622.85glycine receptor alpha 1 [Source:HGNC Symbol;Acc:H... [more]
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BLAST of Neur_chan_LBD domain-containing protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
deg-34.229e-723.04Acetylcholine receptor subunit alpha-type deg-3 [... [more]
deg-34.229e-723.04Acetylcholine receptor subunit alpha-type deg-3 [... [more]
lgc-81.060e-623.23Ligand-Gated ion Channel [Source:UniProtKB/TrEMBL... [more]
lgc-181.339e-621.72Ligand-Gated ion Channel [Source:UniProtKB/TrEMBL... [more]
lgc-91.423e-627.27Ligand-Gated ion Channel [Source:UniProtKB/TrEMBL... [more]
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BLAST of Neur_chan_LBD domain-containing protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Rdl1.317e-623.00gene:FBgn0004244 transcript:FBtr0333836[more]
Rdl1.357e-623.00gene:FBgn0004244 transcript:FBtr0309054[more]
Rdl1.552e-622.65gene:FBgn0004244 transcript:FBtr0333835[more]
Rdl1.552e-622.65gene:FBgn0004244 transcript:FBtr0076534[more]
ort6.043e-624.83gene:FBgn0003011 transcript:FBtr0083784[more]
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BLAST of Neur_chan_LBD domain-containing protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
gabrg19.163e-723.74gamma-aminobutyric acid type A receptor gamma1 sub... [more]
gabrg11.000e-623.74gamma-aminobutyric acid type A receptor gamma1 sub... [more]
glra11.205e-623.22glycine receptor, alpha 1 [Source:NCBI gene;Acc:30... [more]
glra11.332e-623.22glycine receptor, alpha 1 [Source:NCBI gene;Acc:30... [more]
glra11.347e-623.22glycine receptor, alpha 1 [Source:NCBI gene;Acc:30... [more]
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BLAST of Neur_chan_LBD domain-containing protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Neur_chan_LBD domain-containing protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Gabrb36.236e-722.57gamma-aminobutyric acid (GABA) A receptor, subunit... [more]
Gabrb39.442e-722.57gamma-aminobutyric acid (GABA) A receptor, subunit... [more]
Gabrb31.073e-622.57gamma-aminobutyric acid (GABA) A receptor, subunit... [more]
Glra11.496e-622.85glycine receptor, alpha 1 subunit [Source:MGI Symb... [more]
Glra11.555e-622.85glycine receptor, alpha 1 subunit [Source:MGI Symb... [more]
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BLAST of Neur_chan_LBD domain-containing protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 3
Match NameE-valueIdentityDescription
sp|P0C7B7|ELIC_DICCH6.387e-1125.60Cys-loop ligand-gated ion channel OS=Dickeya chrys... [more]
sp|P54244|ACH3_CAEEL5.379e-623.04Acetylcholine receptor subunit alpha-type deg-3 OS... [more]
sp|O93430|GLRA1_DANRE9.100e-623.22Glycine receptor subunit alphaZ1 OS=Danio rerio OX... [more]
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BLAST of Neur_chan_LBD domain-containing protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A0V0J6K79.885e-17173.39Neur_chan_LBD domain-containing protein OS=Schisto... [more]
A0A1S3HM702.815e-11753.94uncharacterized protein LOC106156405 isoform X5 OS... [more]
A0A1S3HLY83.674e-11655.39uncharacterized protein LOC106156405 isoform X4 OS... [more]
A0A1S3HPY91.097e-11555.39uncharacterized protein LOC106156405 isoform X3 OS... [more]
A0A1S3HM641.324e-11554.12uncharacterized protein LOC106156405 isoform X1 OS... [more]
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BLAST of Neur_chan_LBD domain-containing protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
glra26.069e-823.62glycine receptor, alpha 2 [Source:ZFIN;Acc:ZDB-GEN... [more]
glra19.267e-723.22glycine receptor alpha 1 [Source:NCBI gene;Acc:103... [more]
glra11.018e-623.22glycine receptor alpha 1 [Source:NCBI gene;Acc:103... [more]
gabrg12.447e-623.91gamma-aminobutyric acid type A receptor gamma1 sub... [more]
GABRB26.966e-621.51gamma-aminobutyric acid receptor subunit beta-2 [S... [more]
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BLAST of Neur_chan_LBD domain-containing protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 2
Match NameE-valueIdentityDescription
glra4a8.895e-822.45glycine receptor, alpha 4a [Source:ZFIN;Acc:ZDB-GE... [more]
glra29.257e-623.88glycine receptor, alpha 2 [Source:ZFIN;Acc:ZDB-GEN... [more]
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BLAST of Neur_chan_LBD domain-containing protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Neur_chan_LBD domain-containing protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO327901.114e-3229.58Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO268595.877e-1331.06Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO375551.990e-1126.74Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO415389.529e-1026.40Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO431491.539e-824.22Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Neur_chan_LBD domain-containing protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
glra22.464e-825.55glycine receptor alpha 2 [Source:NCBI gene;Acc:101... [more]
glra17.508e-723.60glycine receptor alpha 1 [Source:NCBI gene;Acc:101... [more]
glra17.562e-723.60glycine receptor alpha 1 [Source:NCBI gene;Acc:101... [more]
glra19.053e-723.60glycine receptor alpha 1 [Source:NCBI gene;Acc:101... [more]
gabrg11.428e-623.38gamma-aminobutyric acid type A receptor gamma1 sub... [more]
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BLAST of Neur_chan_LBD domain-containing protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000021796.10.000e+0100.00SMESG000021796.1[more]
SMESG000066647.10.000e+076.49SMESG000066647.1[more]
SMESG000066647.10.000e+068.63SMESG000066647.1[more]
SMESG000039749.10.000e+069.38SMESG000039749.1[more]
SMESG000039749.10.000e+069.38SMESG000039749.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30028543 ID=SMED30028543|Name=Neur_chan_LBD domain-containing protein|organism=Schmidtea mediterranea sexual|type=transcript|length=1376bp
GTTGTTTCCAAAATGTTAATCAATATTTCAAAATAGATTCCTTTAATATT
ATTCAGTAAATGTTTTCTTCGCCTTTAATAAACATTAATGGACTTACTCA
AAACTCTTCTCCACCTGAGACCGTTTTCAGTCCATCTGATGATGCTGCAA
TGCCACTGATCGATGTTAGGAATAGATACAAACACGAAAGTGACAATTAT
AGTGTGAATAATGATGAAAGAATTTTCGGAGATCAAAACAATAGAAAGAG
GCAAGTTTACGTCTGTGTCGTATTCTTAAAAATTGGAGAAATTGATACAA
TTAAAGAACAATATGCAGCAGATATCTTGATAAAATGCAAATGGCGAGAA
CCTAGACTTGATCATAACACTGAAAAATTGGAATATGACTGGGCCAATTC
TTGGACCCCTAAATTGTACATTGAAAATACAATTGGTGAAGCTAAGGAAC
ATGTCTACCAAATGATTATTTTCAATGAGAATCAGCACGCATTTCTTTGC
GAGAAGCGTAGAGTTTCTGGAATATTTTTAGAAAATCTAGAATTAAATCA
TTTTCCTTTCGATGTTCAGGATTTAACAATAACAATAGCATCGAATCTGC
CGTCGACCGAAATCCGACTTGTTAATGATCCAGATGAAACGCATCGAGTA
AACAAACAATCGTTTGTTGATGAGCAAGAATGGTATTTATTCAAACACAT
AGAAACTGAACAGAAAGAATTAGCTTATGAATATGCAGATCCATCTTCCG
TTAAGCCAGCGATCTCAGTGAAATGTCGCGCAGCGAGACGTCCAGCGTAT
TTTATATGGAATATATTTCTAGTTACGTTTCTTATTTGTTCATTGTCGTT
GGTCACATTTGCAGTTGACAAAAGCCTTCCACAGAATCGGTTACAGTTGA
CATTCACATTAGTATTGACATTAGTGGCCTTCAAATTTGTTGTCAACCAA
TGTCTCCCAAAAATATCATATCTCACTTATTTGGATAAATATGTCATTTC
CAGTTTATTCATTCTGACGGTAATTTGTGTTTGGCACGGCATGATAGTAG
TAATAGAAAGATTTGCATCTAAATCAGAATACGATCTTCCAAAAGACATG
GAAATTTACGTTATTATTGGAATGGCGGTCGCTTTTGCAGGGTATAATTT
TGGATTCATTGTCATGATCTATGCGGTGGCTTGCAAAAGGCGTCGAATAA
TGAAACAAAGAGACAAAGAATATTTGGAGCGTCTGCAGTGCCAATTAAAG
TACAAAGGAGCGAGAACGATAAAAATGATTCAACAAACCCATCAAATGCA
CGAAGTCAAAGAAAACAGAAGAGGAACATTTCTGTAAACCTAATTTAAGT
TGCTCATTTCACAATTTTATTCATGC
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protein sequence of SMED30028543-orf-1

>SMED30028543-orf-1 ID=SMED30028543-orf-1|Name=SMED30028543-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=426bp
MFSSPLININGLTQNSSPPETVFSPSDDAAMPLIDVRNRYKHESDNYSVN
NDERIFGDQNNRKRQVYVCVVFLKIGEIDTIKEQYAADILIKCKWREPRL
DHNTEKLEYDWANSWTPKLYIENTIGEAKEHVYQMIIFNENQHAFLCEKR
RVSGIFLENLELNHFPFDVQDLTITIASNLPSTEIRLVNDPDETHRVNKQ
SFVDEQEWYLFKHIETEQKELAYEYADPSSVKPAISVKCRAARRPAYFIW
NIFLVTFLICSLSLVTFAVDKSLPQNRLQLTFTLVLTLVAFKFVVNQCLP
KISYLTYLDKYVISSLFILTVICVWHGMIVVIERFASKSEYDLPKDMEIY
VIIGMAVAFAGYNFGFIVMIYAVACKRRRIMKQRDKEYLERLQCQLKYKG
ARTIKMIQQTHQMHEVKENRRGTFL*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: molecular function
TermDefinition
GO:0004888transmembrane signaling receptor activity
GO:0005216ion channel activity
GO:0005230extracellular ligand-gated ion channel activity
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000099neuron
PLANA:0000418head
PLANA:0000461lateral branch
Vocabulary: INTERPRO
TermDefinition
IPR036734Neur_chan_lig-bd_sf
IPR006201Neur_channel
IPR036719Neuro-gated_channel_TM_sf
IPR006202Neur_chan_lig-bd
IPR006029Neurotrans-gated_channel_TM
Vocabulary: cellular component
TermDefinition
GO:0016020membrane
GO:0016021integral component of membrane
Vocabulary: biological process
TermDefinition
GO:0006810transport
GO:0006811ion transport
GO:0034220ion transmembrane transport
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR036734Neurotransmitter-gated ion-channel ligand-binding domain superfamilyGENE3DG3DSA:2.70.170.10coord: 57..240
e-value: 5.1E-22
score: 80.3
IPR036734Neurotransmitter-gated ion-channel ligand-binding domain superfamilySUPERFAMILYSSF63712Nicotinic receptor ligand binding domain-likecoord: 59..214
IPR006202Neurotransmitter-gated ion-channel ligand-binding domainPFAMPF02931Neur_chan_LBDcoord: 61..229
e-value: 6.0E-10
score: 38.9
NoneNo IPR availableGENE3DG3DSA:1.20.58.390coord: 245..393
e-value: 9.8E-20
score: 72.7
NoneNo IPR availablePANTHERPTHR18945:SF768coord: 51..339
NoneNo IPR availableCDDcd18988LGIC_ECD_bactcoord: 65..204
e-value: 8.99745E-22
score: 90.0446
NoneNo IPR availableCDDcd19050LGIC_TM_bactcoord: 247..343
e-value: 1.12665E-18
score: 79.1746
NoneNo IPR availableTMHMMTMhelixcoord: 246..268
NoneNo IPR availableTMHMMTMhelixcoord: 313..332
NoneNo IPR availableTMHMMTMhelixcoord: 278..300
NoneNo IPR availableTMHMMTMhelixcoord: 352..374
IPR006201Neurotransmitter-gated ion-channelPANTHERPTHR18945NEUROTRANSMITTER GATED ION CHANNELcoord: 51..339
IPR036719Neurotransmitter-gated ion-channel transmembrane domain superfamilySUPERFAMILYSSF90112Neurotransmitter-gated ion-channel transmembrane porecoord: 245..325