Innexin

Overview
NameInnexin
Smed IDSMED30028531
Length (bp)1571
Neoblast Clusters

Zeng et. al., 2018




▻ Overview

▻ Neoblast Population

 



 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)




Explore this single cell expression dataset with our NB Cluster Shiny App




 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Innexin (SMED30028531) t-SNE clustered cells

Violin plots show distribution of expression levels for Innexin (SMED30028531) in cells (dots) of each of the 12 neoblast clusters.

 

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Embryonic Expression

Davies et. al., 2017




Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020




SMED30028531

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 4

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
prepharyngeal regionSMED30028531h1SMcG0017344 SmedASXL_062224SmedAsxl_ww_GCZZ01PMID:27034770
Currie et al., 2016
whole organism asexual adult RNA-sequencing evidence
Smed sexual biotypeSMED30028531h1SMcG0017344 Contig38568newmark_estsPMID:29674431
Fincher et al., 2018
FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30028531h1SMcG0017344 Contig38568uc_Smed_v2PMID:29674431
Fincher et al., 2018
FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
gutSMED30028531h1SMcG0017344 dd_Smed_v4_26703_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
BLAST of Innexin vs. Ensembl Celegans
Match: inx-13 (Innexin [Source:UniProtKB/TrEMBL;Acc:O44887])

HSP 1 Score: 186.422 bits (472), Expect = 1.106e-53
Identity = 114/400 (28.50%), Postives = 209/400 (52.25%), Query Frame = 3
Query:  228 LNAVHNYGLEDLADKMXXXXXXXXXXXXXXXXXXKSYVIKPISCYLSIGPSGGNFQDYIENYCWIHGTIPLYPNQKLSDNHVGWDELERTQKINYYQWVPFILGLQCIMFYIPKLIWQIFCFNQAGTNLDTIIKLSMKMAEIPISERRVENENIAKIIENMLVLHRDFRDSKIANIRRSVYSKCSLFMSSKRLGTMIVFSYFVTKLLYLTNGIGQLFMIQSVLGFYNYLPTFGSHLFWY------IVSGTELETQHYFPRVVFCYLKRIRHVGVQNNYVAQCVLPVNMLNEKIYTFLWCWILLVSFATFISIPLWINRLYRADVREHYIGNFLQMLNSYDEHKK---PLIHKFINDFLRHDGLFLLRMISNNAGDLIAAYLVNNLWDIYLKKYQNRNLRK 1400
            L  +H  G +D  D+++  ++ ++L +    ++ K YV +PI C++    +G  ++ Y ENYC++  T  + P++ + D+ +  +  E    I YYQWVPFILGLQ I+FY+P L W++  FN +G  L  ++  + K   +    R    ++    +   L L   F          + Y+    +      G+ + + Y   K LYL   + Q  ++ + LG         S+ FW       I++G E E   +FPRV  C  + +R +G ++ +  QCVL +NM NEK+Y FLW W+++V  ATF+++  W  +L     R+ +I ++LQ+ +++ +       ++ KF++  L+ DG+F+  +I NN G + +  ++ ++WD +L+   NR+ +K
Sbjct:    8 LKGLHKQGDDDSIDRLNYYWTPMLLVIFALTLSAKQYVGQPIQCWIPAQFTGA-WEQYSENYCFVQNTYFISPDKYIPDSEIDREGAE----IGYYQWVPFILGLQAILFYLPSLFWRLMNFN-SGVALKKMLFGAKKADRVDEKARNEAAKSTGAHLYESLTLQSRF----------AKYTSAFTYG-----GSYLTYLYLFVKFLYLVQIVFQFIILNNFLG--------TSYTFWGLGILSDILNGREWEESGHFPRVTMCDFE-VRVLGNKHRHTVQCVLMINMFNEKVYVFLWFWLVIVGVATFLNLVNWTRKLMFRSARKAHIKSYLQIEDNFSDDNSRNGQILDKFVDYKLKSDGVFITHLIDNNGGSVFSHDVIVDMWDRFLQDEDNRSQKK 377          
BLAST of Innexin vs. Ensembl Celegans
Match: inx-18 (Innexin [Source:UniProtKB/TrEMBL;Acc:Q8MXG8])

HSP 1 Score: 185.267 bits (469), Expect = 4.953e-53
Identity = 117/374 (31.28%), Postives = 199/374 (53.21%), Query Frame = 3
Query:  255 EDLADKMXXXXXXXXXXXXXXXXXXKSYVIKPISCYLSIGPSGGNFQDYIENYCWIHGTIPLYPNQKLSDNHVGWDELERTQKINYYQWVPFILGLQCIMFYIPKLIWQIFCFNQAGTNLDTIIKLSMKMAEIPISERRVENENIAKIIENMLVLHRDFRDSKIANIRRSVYSKCSLFMSSKRLGTMIVFSYFVTKLLYLTNGIGQLFMIQSVLGFYNYLPTFGSHLFWYIVSGTELETQHYFPRVVFCYLKRIRHVGVQNNYVAQCVLPVNMLNEKIYTFLWCWILLVSFATFISIPLWINRLYRADVREHYIGNFLQMLNSYDEHKKPLIHKFINDFLRHDGLFLLRMISNNAGDLIAAYLVNNLWDIYLKK 1376
            +D  D++  +++  ++ +   +V+ K YV  PI C++    +    + Y ENYCW+  T  + P Q L  + +  D+ ER Q I YYQWVPF+L +  + F+IP  +W++    Q+G N   +++L      +    R    + +A+ I++ L+  RD         R SVY   ++F   K  G  +   Y   K L+L N I Q  ++ S L   +Y P FG+H+ + +  G E      FPRV  C  + IR +G  + +  QCVL +NML EKI+ FLW W+ +++  T +++  W   L     REH++   L +       +   I +F++ FLR DG+FLL+MI++++G+L+AA +   LW I++++
Sbjct:   25 DDFVDRLHYLYTSTMVLMFAVLVSAKQYVGHPIECFVPAQFTRA-MEQYTENYCWVQNTYWV-PFQDLIPHRL--DDRERRQ-IGYYQWVPFVLAVAALTFHIPSSVWRMLA-GQSGLNAGLVLQLVCGDENVDPVVRDKTVDIVARHIDDALMYQRDH-----GARRHSVYI-FAIFKLGKFYGAYVSSVYIFIKALHLANVILQFMLLNSFLQTSDY-PMFGAHVLYDLFMGREWRDSGKFPRVTLCDFE-IRVLGNVHRHTVQCVLVINMLTEKIFIFLWLWLTVLAIVTALNLIFWFIALVSNSCREHFVSKHLDI-------QSDQISRFVHRFLRADGVFLLQMIASHSGNLMAAKVTEQLWMIFVRR 377          
BLAST of Innexin vs. Ensembl Celegans
Match: inx-18 (Innexin [Source:UniProtKB/TrEMBL;Acc:Q8MXG8])

HSP 1 Score: 185.267 bits (469), Expect = 4.953e-53
Identity = 117/374 (31.28%), Postives = 199/374 (53.21%), Query Frame = 3
Query:  255 EDLADKMXXXXXXXXXXXXXXXXXXKSYVIKPISCYLSIGPSGGNFQDYIENYCWIHGTIPLYPNQKLSDNHVGWDELERTQKINYYQWVPFILGLQCIMFYIPKLIWQIFCFNQAGTNLDTIIKLSMKMAEIPISERRVENENIAKIIENMLVLHRDFRDSKIANIRRSVYSKCSLFMSSKRLGTMIVFSYFVTKLLYLTNGIGQLFMIQSVLGFYNYLPTFGSHLFWYIVSGTELETQHYFPRVVFCYLKRIRHVGVQNNYVAQCVLPVNMLNEKIYTFLWCWILLVSFATFISIPLWINRLYRADVREHYIGNFLQMLNSYDEHKKPLIHKFINDFLRHDGLFLLRMISNNAGDLIAAYLVNNLWDIYLKK 1376
            +D  D++  +++  ++ +   +V+ K YV  PI C++    +    + Y ENYCW+  T  + P Q L  + +  D+ ER Q I YYQWVPF+L +  + F+IP  +W++    Q+G N   +++L      +    R    + +A+ I++ L+  RD         R SVY   ++F   K  G  +   Y   K L+L N I Q  ++ S L   +Y P FG+H+ + +  G E      FPRV  C  + IR +G  + +  QCVL +NML EKI+ FLW W+ +++  T +++  W   L     REH++   L +       +   I +F++ FLR DG+FLL+MI++++G+L+AA +   LW I++++
Sbjct:   25 DDFVDRLHYLYTSTMVLMFAVLVSAKQYVGHPIECFVPAQFTRA-MEQYTENYCWVQNTYWV-PFQDLIPHRL--DDRERRQ-IGYYQWVPFVLAVAALTFHIPSSVWRMLA-GQSGLNAGLVLQLVCGDENVDPVVRDKTVDIVARHIDDALMYQRDH-----GARRHSVYI-FAIFKLGKFYGAYVSSVYIFIKALHLANVILQFMLLNSFLQTSDY-PMFGAHVLYDLFMGREWRDSGKFPRVTLCDFE-IRVLGNVHRHTVQCVLVINMLTEKIFIFLWLWLTVLAIVTALNLIFWFIALVSNSCREHFVSKHLDI-------QSDQISRFVHRFLRADGVFLLQMIASHSGNLMAAKVTEQLWMIFVRR 377          
BLAST of Innexin vs. Ensembl Celegans
Match: inx-19 (Innexin-19 [Source:UniProtKB/Swiss-Prot;Acc:O61715])

HSP 1 Score: 186.037 bits (471), Expect = 5.804e-53
Identity = 138/430 (32.09%), Postives = 227/430 (52.79%), Query Frame = 3
Query:  228 LNAVHNYGLEDLADKMXXXXXXXXXXXXXXXXXXKSYVIKPISCYLSIGP-SGGNFQDYIENYCWIHGT--IPLYPNQKLSDNHVGWDELERTQKINYYQWVPFILGLQCIMFYIPKLIWQIFCFNQAGTNLDTIIKLSMK-MAEIPISERRVENENIAK-IIENMLVLHRDFRDSKIANIRRSVYSKCSLFMSSKRLGTMIVFSYFVTKLLYLTNGIGQLFMIQSVLGFYNYLPTFGSHLFWYIVSGTELETQHYFPRVVFCYLKRIRHVGVQNNYVAQCVLPVNMLNEKIYTFLWCWILLVSFATFISIPLWINRLYRADVREHYIGNFLQMLNSYDEHKK---------------------PLIHKFINDFLRHDGLFLLRMISNNAGDLIAAYLVNNLWDIYLKKYQNRNLRKDIFSVSNHLKEDE 1439
            +NA+   G +D  D+++  ++ LIL+VC  +++ K Y   PI C+  + P S  + ++YIE+YCWI  T  IP+Y N  + D+H   +E    ++I YYQWVPFIL  + +MF +P + W++ C  Q+G N+ T+I  +    A +  S+R+   E I    ++N+ +   + R      I R  +S+   F+S + L  +  F    TKLLY  N + Q  ++ + L   ++L  FG  +   I +G       +FPRV  C  + +R++   N Y  QC L +N++NEK++ FLWCW ++++  T  S   WI   +    +  Y+  F+Q+  S  E KK                      L+  F++DFL+ DG+ +LRMISN+AGD+I   LV NLW    ++++ RN R+  F     +K+ E
Sbjct:   12 INALSVRGDDDAVDRLNYYYTPLILAVCCLVISAKQYGGTPIECW--VNPHSRESMEEYIESYCWIQNTYWIPMYEN--VPDDHTAREE----KQIGYYQWVPFILIAEALMFSLPCIFWRL-CSFQSGLNIQTLINAACDGQALLDASDRQKAVEAITTNFVDNLDLQSPNGRIRARGWIARIKFSR---FLSGQCLSILHSF----TKLLYSMNVVAQFLILNACLKSSDFL-FFGFQVLNDIWAGRPWTETGHFPRVTLCDFE-VRYLANLNRYTVQCALLINIINEKVFAFLWCWYMILAIITTCSFIYWIANSFIHSEKVDYVMKFIQIAES-SEFKKLQKFEKDATVERLYTVIAFAPHLLDTFVSDFLKSDGVLMLRMISNHAGDMIVVQLVRNLW----QEFRERNWRE--FEEHEEMKDVE 416          
BLAST of Innexin vs. Ensembl Celegans
Match: inx-18 (Innexin [Source:UniProtKB/TrEMBL;Acc:Q8MXG8])

HSP 1 Score: 185.652 bits (470), Expect = 6.968e-53
Identity = 117/374 (31.28%), Postives = 199/374 (53.21%), Query Frame = 3
Query:  255 EDLADKMXXXXXXXXXXXXXXXXXXKSYVIKPISCYLSIGPSGGNFQDYIENYCWIHGTIPLYPNQKLSDNHVGWDELERTQKINYYQWVPFILGLQCIMFYIPKLIWQIFCFNQAGTNLDTIIKLSMKMAEIPISERRVENENIAKIIENMLVLHRDFRDSKIANIRRSVYSKCSLFMSSKRLGTMIVFSYFVTKLLYLTNGIGQLFMIQSVLGFYNYLPTFGSHLFWYIVSGTELETQHYFPRVVFCYLKRIRHVGVQNNYVAQCVLPVNMLNEKIYTFLWCWILLVSFATFISIPLWINRLYRADVREHYIGNFLQMLNSYDEHKKPLIHKFINDFLRHDGLFLLRMISNNAGDLIAAYLVNNLWDIYLKK 1376
            +D  D++  +++  ++ +   +V+ K YV  PI C++    +    + Y ENYCW+  T  + P Q L  + +  D+ ER Q I YYQWVPF+L +  + F+IP  +W++    Q+G N   +++L      +    R    + +A+ I++ L+  RD         R SVY   ++F   K  G  +   Y   K L+L N I Q  ++ S L   +Y P FG+H+ + +  G E      FPRV  C  + IR +G  + +  QCVL +NML EKI+ FLW W+ +++  T +++  W   L     REH++   L +       +   I +F++ FLR DG+FLL+MI++++G+L+AA +   LW I++++
Sbjct:   25 DDFVDRLHYLYTSTMVLMFAVLVSAKQYVGHPIECFVPAQFTRA-MEQYTENYCWVQNTYWV-PFQDLIPHRL--DDRERRQ-IGYYQWVPFVLAVAALTFHIPSSVWRMLA-GQSGLNAGLVLQLVCGDENVDPVVRDKTVDIVARHIDDALMYQRDH-----GARRHSVYI-FAIFKLGKFYGAYVSSVYIFIKALHLANVILQFMLLNSFLQTSDY-PMFGAHVLYDLFMGREWRDSGKFPRVTLCDFE-IRVLGNVHRHTVQCVLVINMLTEKIFIFLWLWLTVLAIVTALNLIFWFIALVSNSCREHFVSKHLDI-------QSDQISRFVHRFLRADGVFLLQMIASHSGNLMAAKVTEQLWMIFVRR 377          
BLAST of Innexin vs. Ensembl Fly
Match: Inx2 (gene:FBgn0027108 transcript:FBtr0301860)

HSP 1 Score: 88.9669 bits (219), Expect = 6.183e-19
Identity = 80/292 (27.40%), Postives = 127/292 (43.49%), Query Frame = 3
Query:  330 KSYVIKPISCYLSIGPSGGNFQDYIENYCWIHGTIPLYPN----------QKLSDNHV-GWDELERTQKINYYQWVPFILGLQCIMFYIPKLIWQIFCFNQAGTNLDTIIKLSMKMAEI--PISERRVENENIAKIIENMLVLHRDFRDSKIANIRRSVYSKCSLFMSSKRLGTMIVFSYFVTKLLYLTNGIGQLFMIQSVLGFYNYLPTFGSHLFWYIVSGTELETQH-------YFPRVVFCYLKRIRHVGVQNNYVAQCVLPVNMLNEKIYTFLWCWILLVSFATFISI 1145
            + Y+  PI C +   P G      ++ YCWI+ T  +             Q    +HV G DE++  +   YYQWV F+L  Q I+FY+P+ +W+ +   + G       +L M + ++  PI     +N+      + +LV      D  I N+ R                    F +FV + L   N IGQ++ +   L       T+GS +  +    TELE           FP+V  C   +    G    +   CVLP+N++NEKIY FLW W +++S  + IS+
Sbjct:   45 RQYIGDPIDCIVDEIPLG-----VMDTYCWIYSTFTVPERLTGITGRDVVQPGVGSHVEGEDEVKYHK---YYQWVCFVLFFQAILFYVPRYLWKSW---EGG-------RLKMLVMDLNSPIVNDECKNDR-----KKILV------DYFIGNLNRH---------------NFYAFRFFVCEALNFVNVIGQIYFVDFFLD--GEFSTYGSDVLKF----TELEPDERIDPMARVFPKVTKCTFHKYGPSGSVQTHDGLCVLPLNIVNEKIYVFLWFWFIILSIMSGISL 286          
BLAST of Innexin vs. Ensembl Fly
Match: Inx2 (gene:FBgn0027108 transcript:FBtr0071005)

HSP 1 Score: 88.9669 bits (219), Expect = 6.183e-19
Identity = 80/292 (27.40%), Postives = 127/292 (43.49%), Query Frame = 3
Query:  330 KSYVIKPISCYLSIGPSGGNFQDYIENYCWIHGTIPLYPN----------QKLSDNHV-GWDELERTQKINYYQWVPFILGLQCIMFYIPKLIWQIFCFNQAGTNLDTIIKLSMKMAEI--PISERRVENENIAKIIENMLVLHRDFRDSKIANIRRSVYSKCSLFMSSKRLGTMIVFSYFVTKLLYLTNGIGQLFMIQSVLGFYNYLPTFGSHLFWYIVSGTELETQH-------YFPRVVFCYLKRIRHVGVQNNYVAQCVLPVNMLNEKIYTFLWCWILLVSFATFISI 1145
            + Y+  PI C +   P G      ++ YCWI+ T  +             Q    +HV G DE++  +   YYQWV F+L  Q I+FY+P+ +W+ +   + G       +L M + ++  PI     +N+      + +LV      D  I N+ R                    F +FV + L   N IGQ++ +   L       T+GS +  +    TELE           FP+V  C   +    G    +   CVLP+N++NEKIY FLW W +++S  + IS+
Sbjct:   45 RQYIGDPIDCIVDEIPLG-----VMDTYCWIYSTFTVPERLTGITGRDVVQPGVGSHVEGEDEVKYHK---YYQWVCFVLFFQAILFYVPRYLWKSW---EGG-------RLKMLVMDLNSPIVNDECKNDR-----KKILV------DYFIGNLNRH---------------NFYAFRFFVCEALNFVNVIGQIYFVDFFLD--GEFSTYGSDVLKF----TELEPDERIDPMARVFPKVTKCTFHKYGPSGSVQTHDGLCVLPLNIVNEKIYVFLWFWFIILSIMSGISL 286          
BLAST of Innexin vs. Ensembl Fly
Match: Inx2 (gene:FBgn0027108 transcript:FBtr0332314)

HSP 1 Score: 88.9669 bits (219), Expect = 6.183e-19
Identity = 80/292 (27.40%), Postives = 127/292 (43.49%), Query Frame = 3
Query:  330 KSYVIKPISCYLSIGPSGGNFQDYIENYCWIHGTIPLYPN----------QKLSDNHV-GWDELERTQKINYYQWVPFILGLQCIMFYIPKLIWQIFCFNQAGTNLDTIIKLSMKMAEI--PISERRVENENIAKIIENMLVLHRDFRDSKIANIRRSVYSKCSLFMSSKRLGTMIVFSYFVTKLLYLTNGIGQLFMIQSVLGFYNYLPTFGSHLFWYIVSGTELETQH-------YFPRVVFCYLKRIRHVGVQNNYVAQCVLPVNMLNEKIYTFLWCWILLVSFATFISI 1145
            + Y+  PI C +   P G      ++ YCWI+ T  +             Q    +HV G DE++  +   YYQWV F+L  Q I+FY+P+ +W+ +   + G       +L M + ++  PI     +N+      + +LV      D  I N+ R                    F +FV + L   N IGQ++ +   L       T+GS +  +    TELE           FP+V  C   +    G    +   CVLP+N++NEKIY FLW W +++S  + IS+
Sbjct:   45 RQYIGDPIDCIVDEIPLG-----VMDTYCWIYSTFTVPERLTGITGRDVVQPGVGSHVEGEDEVKYHK---YYQWVCFVLFFQAILFYVPRYLWKSW---EGG-------RLKMLVMDLNSPIVNDECKNDR-----KKILV------DYFIGNLNRH---------------NFYAFRFFVCEALNFVNVIGQIYFVDFFLD--GEFSTYGSDVLKF----TELEPDERIDPMARVFPKVTKCTFHKYGPSGSVQTHDGLCVLPLNIVNEKIYVFLWFWFIILSIMSGISL 286          
BLAST of Innexin vs. Ensembl Fly
Match: Inx2 (gene:FBgn0027108 transcript:FBtr0071006)

HSP 1 Score: 88.9669 bits (219), Expect = 6.183e-19
Identity = 80/292 (27.40%), Postives = 127/292 (43.49%), Query Frame = 3
Query:  330 KSYVIKPISCYLSIGPSGGNFQDYIENYCWIHGTIPLYPN----------QKLSDNHV-GWDELERTQKINYYQWVPFILGLQCIMFYIPKLIWQIFCFNQAGTNLDTIIKLSMKMAEI--PISERRVENENIAKIIENMLVLHRDFRDSKIANIRRSVYSKCSLFMSSKRLGTMIVFSYFVTKLLYLTNGIGQLFMIQSVLGFYNYLPTFGSHLFWYIVSGTELETQH-------YFPRVVFCYLKRIRHVGVQNNYVAQCVLPVNMLNEKIYTFLWCWILLVSFATFISI 1145
            + Y+  PI C +   P G      ++ YCWI+ T  +             Q    +HV G DE++  +   YYQWV F+L  Q I+FY+P+ +W+ +   + G       +L M + ++  PI     +N+      + +LV      D  I N+ R                    F +FV + L   N IGQ++ +   L       T+GS +  +    TELE           FP+V  C   +    G    +   CVLP+N++NEKIY FLW W +++S  + IS+
Sbjct:   45 RQYIGDPIDCIVDEIPLG-----VMDTYCWIYSTFTVPERLTGITGRDVVQPGVGSHVEGEDEVKYHK---YYQWVCFVLFFQAILFYVPRYLWKSW---EGG-------RLKMLVMDLNSPIVNDECKNDR-----KKILV------DYFIGNLNRH---------------NFYAFRFFVCEALNFVNVIGQIYFVDFFLD--GEFSTYGSDVLKF----TELEPDERIDPMARVFPKVTKCTFHKYGPSGSVQTHDGLCVLPLNIVNEKIYVFLWFWFIILSIMSGISL 286          
BLAST of Innexin vs. Ensembl Fly
Match: Inx3 (gene:FBgn0265274 transcript:FBtr0085350)

HSP 1 Score: 78.1814 bits (191), Expect = 2.746e-15
Identity = 71/277 (25.63%), Postives = 116/277 (41.88%), Query Frame = 3
Query:  348 PISCYLSIGPSGGNFQDYIENYCWIHGT--IPLYPNQKLSDNHVG---WDELERTQKI-NYYQWVPFILGLQCIMFYIPKLIWQIFCFNQAGTNLDTIIKLSMKMAEIPISERRVENENIAKIIENMLVLHRDFRDSKIANIRRSVYSKCSLFMSSKRLGTMIVFSYFVTKLLYLTNGIGQLFMIQSVLGFYNYLPTFGSHLFWYIVSGTELETQ-----HYFPRVVFCYLKRIRHVGVQNNYVAQCVLPVNMLNEKIYTFLWCWILLVSFATFISI 1145
            PISC       G      I  +CWI  T  IP   ++++  +  G    +E  + ++  +YYQWVPF+L  Q +MFY+P  +W+    N     +  I      M  +P   RR   + I K   N L  H  +                              F+YF  +LL   N I  +FM+   LG      ++G+ +  +  S  + + +       FPR+  C   +    G    +   CVL +N+LNEKIY FLW W ++++  + +++
Sbjct:   57 PISCI----NDGAIPMHVINTFCWITYTYTIPGQQHRQIGTDVAGPGLGNEYGQEKRYHSYYQWVPFVLFFQGLMFYVPHWVWK----NMEDGKIRMITDGLRGMVSVPDDYRRDRQDRILKYFVNSLNTHNGYS-----------------------------FAYFFCELLNFINVIVNIFMVDKFLG--GAFMSYGTDVLKF--SNMDQDKRFDPMIEIFPRLTKCTFHKFGPSGSVQKHDTLCVLALNILNEKIYIFLWFWFIILATISGVAV 292          
BLAST of Innexin vs. UniProt/SwissProt
Match: sp|A8WVX4|INX19_CAEBR (Innexin-19 OS=Caenorhabditis briggsae OX=6238 GN=inx-19 PE=3 SV=3)

HSP 1 Score: 189.504 bits (480), Expect = 3.181e-53
Identity = 139/430 (32.33%), Postives = 227/430 (52.79%), Query Frame = 3
Query:  228 LNAVHNYGLEDLADKMXXXXXXXXXXXXXXXXXXKSYVIKPISCYLSIGP-SGGNFQDYIENYCWIHGT--IPLYPNQKLSDNHVGWDELERTQKINYYQWVPFILGLQCIMFYIPKLIWQIFCFNQAGTNLDTIIKLSM-KMAEIPISERRVENENIA-KIIENMLVLHRDFRDSKIANIRRSVYSKCSLFMSSKRLGTMIVFSYFVTKLLYLTNGIGQLFMIQSVLGFYNYLPTFGSHLFWYIVSGTELETQHYFPRVVFCYLKRIRHVGVQNNYVAQCVLPVNMLNEKIYTFLWCWILLVSFATFISIPLWINRLYRADVREHYIGNFLQMLNSYDEHKK---------------------PLIHKFINDFLRHDGLFLLRMISNNAGDLIAAYLVNNLWDIYLKKYQNRNLRKDIFSVSNHLKEDE 1439
            ++A+   G +D  D+++  ++ LIL+VC  +++ K Y   PI C+  + P S  + ++YIE+YCWI  T  IP+Y N  + D+H   +E    ++I YYQWVPFIL  + +MF +P + W++ C  Q+G N+ T+I  +    A +  S+R+   E I    ++N+ +   + R      I R  +S+   F+S    G  I   Y  TKLLY  N + Q F++ + L    ++  FG  +   I +G       +FPRV  C  + +R++   N Y  QC L +N++NEK++ FLWCW ++++  T  S   WI   +    +  Y+  F+Q+  S  E+KK                      L+  F++DFL+ DG+ +LRMISN+AGD+I   LV NLW    ++Y+ RN R+  F     +K+ E
Sbjct:   12 ISALSVRGDDDAVDRLNYYYTPLILAVCCLVISAKQYGGTPIECW--VNPHSRESMEEYIESYCWIQNTYWIPMYEN--VPDDHTAREE----KQIGYYQWVPFILIAEALMFSLPCIFWRL-CSFQSGLNIQTLINAACDAQALLDYSDRQKAVEAITCNFVDNLDLQSPNGRIRARGWIARIKFSR---FLS----GQCISIVYSFTKLLYSVNVVAQFFILNACLKSSEFV-FFGFQVLSDIWAGRPWTETGHFPRVTLCDFE-VRYLANLNRYTVQCALLINIINEKVFAFLWCWYMILAIITTCSFIYWIANSFIHSEKVDYVMKFIQIAES-SEYKKLQKFEKDATVERLYTVIAFAPHLLDSFVSDFLKSDGILMLRMISNHAGDMIVVQLVRNLW----QEYRERNWRE--FEEHEEMKDVE 416          
BLAST of Innexin vs. UniProt/SwissProt
Match: sp|O61715|INX19_CAEEL (Innexin-19 OS=Caenorhabditis elegans OX=6239 GN=inx-19 PE=1 SV=2)

HSP 1 Score: 186.037 bits (471), Expect = 9.363e-52
Identity = 138/430 (32.09%), Postives = 227/430 (52.79%), Query Frame = 3
Query:  228 LNAVHNYGLEDLADKMXXXXXXXXXXXXXXXXXXKSYVIKPISCYLSIGP-SGGNFQDYIENYCWIHGT--IPLYPNQKLSDNHVGWDELERTQKINYYQWVPFILGLQCIMFYIPKLIWQIFCFNQAGTNLDTIIKLSMK-MAEIPISERRVENENIAK-IIENMLVLHRDFRDSKIANIRRSVYSKCSLFMSSKRLGTMIVFSYFVTKLLYLTNGIGQLFMIQSVLGFYNYLPTFGSHLFWYIVSGTELETQHYFPRVVFCYLKRIRHVGVQNNYVAQCVLPVNMLNEKIYTFLWCWILLVSFATFISIPLWINRLYRADVREHYIGNFLQMLNSYDEHKK---------------------PLIHKFINDFLRHDGLFLLRMISNNAGDLIAAYLVNNLWDIYLKKYQNRNLRKDIFSVSNHLKEDE 1439
            +NA+   G +D  D+++  ++ LIL+VC  +++ K Y   PI C+  + P S  + ++YIE+YCWI  T  IP+Y N  + D+H   +E    ++I YYQWVPFIL  + +MF +P + W++ C  Q+G N+ T+I  +    A +  S+R+   E I    ++N+ +   + R      I R  +S+   F+S + L  +  F    TKLLY  N + Q  ++ + L   ++L  FG  +   I +G       +FPRV  C  + +R++   N Y  QC L +N++NEK++ FLWCW ++++  T  S   WI   +    +  Y+  F+Q+  S  E KK                      L+  F++DFL+ DG+ +LRMISN+AGD+I   LV NLW    ++++ RN R+  F     +K+ E
Sbjct:   28 INALSVRGDDDAVDRLNYYYTPLILAVCCLVISAKQYGGTPIECW--VNPHSRESMEEYIESYCWIQNTYWIPMYEN--VPDDHTAREE----KQIGYYQWVPFILIAEALMFSLPCIFWRL-CSFQSGLNIQTLINAACDGQALLDASDRQKAVEAITTNFVDNLDLQSPNGRIRARGWIARIKFSR---FLSGQCLSILHSF----TKLLYSMNVVAQFLILNACLKSSDFL-FFGFQVLNDIWAGRPWTETGHFPRVTLCDFE-VRYLANLNRYTVQCALLINIINEKVFAFLWCWYMILAIITTCSFIYWIANSFIHSEKVDYVMKFIQIAES-SEFKKLQKFEKDATVERLYTVIAFAPHLLDTFVSDFLKSDGVLMLRMISNHAGDMIVVQLVRNLW----QEFRERNWRE--FEEHEEMKDVE 432          
BLAST of Innexin vs. UniProt/SwissProt
Match: sp|O01393|UNC9_CAEEL (Innexin unc-9 OS=Caenorhabditis elegans OX=6239 GN=unc-9 PE=1 SV=1)

HSP 1 Score: 180.644 bits (457), Expect = 2.267e-50
Identity = 112/379 (29.55%), Postives = 202/379 (53.30%), Query Frame = 3
Query:  255 EDLADKMXXXXXXXXXXXXXXXXXXKSYVIKPISCYLSIGPSGGNFQDYIENYCWIHGTIPLYPNQKLSDNHVGWDELERTQKINYYQWVPFILGLQCIMFYIPKLIWQIFCFNQAGTNLDTIIKLSMKMAEIPISERRVENENIAKIIENML-VLHRDFRDSKIANIRRSVYSKCSLFMSSKRLGTMIVFSYFVTKLLYLTNGIGQLFMIQSVLGFYNYLPTFGSHLFWYIVSGTELETQHYFPRVVFCYLKRIRHVGVQNNYVAQCVLPVNMLNEKIYTFLWCWILLVSFATFISIPLWINRLYRADVREHYIGNFLQMLNSYDEHKKPLIHKFINDFLRHDGLFLLRMISNNAGDLIAAYLVNNLWDIYLKKYQNR 1388
            +D+ DK++  ++  I++V   +V+ K YV  PI C++         + Y ENYCW+  T  L  +  +  N+    E E  Q I YYQWVPF+L L+ ++FY+P ++W++  + Q+G ++ ++++++     + +  R    + IA  +E  L V H+    +++  +        +L + ++  G  + F Y   K+LY  N +GQ+F++ + LG  N    +G  +   +++G E E   +FPRV  C  + ++ +G  + +  QCVL +NM NEKI+ FLW W  L++ AT  S+  WI        + +++G +L  +  Y       + +F+  FLR DG+FLLRM++ +AG+L    L   LW+ Y    + +
Sbjct:   21 DDIIDKLNYYYTTAIITVFAILVSAKQYVGFPIQCWVP-ATFTEPMEQYTENYCWVQNTYFLPLHDYIPHNYA---ERENRQ-IGYYQWVPFVLALEALLFYVPTIVWRLLSW-QSGIHVQSLVQMACDSRLLDLESRNRALQTIATNVEEALHVKHQVMSGNRLKLL--------NLIICTRSSGAAVTFLYISVKILYTVNIVGQIFLLNTFLG--NRSKWYGLQVLNDLMNGREWEESGHFPRVTLCDFE-VKVLGNVHRHTVQCVLMINMFNEKIFLFLWFWYFLLAGATLCSLFYWIYISVVPSRQLNFVGKYLTGIEGYKMVDSQSLRRFVFHFLRQDGVFLLRMVATHAGELPCYELAKTLWNNYCDNKEGK 382          
BLAST of Innexin vs. UniProt/SwissProt
Match: sp|Q03412|UNC7_CAEEL (Innexin unc-7 OS=Caenorhabditis elegans OX=6239 GN=unc-7 PE=1 SV=1)

HSP 1 Score: 166.392 bits (420), Expect = 5.403e-44
Identity = 120/404 (29.70%), Postives = 204/404 (50.50%), Query Frame = 3
Query:  195 VANEFFSLINRLNAVHNYGLEDLADKMXXXXXXXXXXXXXXXXXXKSYVIKPISCYLSIGPSGGNFQDYIENYCWIHGT--IPLY---PNQKLSDNHVGWDELERTQKINYYQWVPFILGLQCIMFYIPKLIWQIFCFNQAGTNLDTIIKLSMKMAEIPISERRVENENIAKIIENMLVLHRDFRDSKIANI-----RRSVYSKCSLFMSSKR-LGTMIVFSYFVTKLLYLTNGIGQLFMIQSVLGFYNYLPTFGSHLFWYIVSGTELETQHYFPRVVFCYLKRIRHVGVQNNYVAQCVLPVNMLNEKIYTFLWCWILLVSFATFISIPLWINRLYRADVREHYIGNFLQMLNSYDEHKKPL-----IHKFINDFLRHDGLFLLRMISNNAGDLIAAYLVNNLW 1358
            +A+ F +L  RL+       +D  DK++  ++  IL+    +V+ K YV  PI C++    +    + Y ENYCW+  T  +P+    P +  S          R ++I YYQWVPFIL ++ ++FY+P ++W+   +  +G NL  +++++          R +++E   + +  M    +D  + ++ NI      RS +S   L  +  R  G  +   Y   K+LY  N + Q F++  +LG  +    +G  L   ++   E E    FPRV  C  + +R +G  + +  QCVL +NM NEKI+ FLW W L     T  +   WI  ++       ++  +L++L   D   KP+     + KF N+FLR DG+F+LRMIS +AG+L+++ L+  LW
Sbjct:  126 LASAFRALYPRLD-------DDFVDKLNYYYTTTILASFALLVSAKQYVGFPIQCWVPATFTDA-MEQYTENYCWVQNTYWVPMQEDIPREIYS---------RRNRQIGYYQWVPFILAIEALLFYVPCILWRGLLYWHSGINLQGLVQMA-------CDARLMDSEIKTRTVYTMARHMQD--EVQLTNIDRQGHSRSCFSNLQLGANCGRHCGCYVTMLYIGIKVLYSANVLLQFFLLNHLLGSNDL--AYGFSLLKDLMHAIEWEQTGMFPRVTLCDFE-VRVLGNIHRHTVQCVLMINMFNEKIFLFLWFWFLTCGIVTVCNTMYWILIMFIPSQGMSFVRKYLRVLP--DHPAKPIADDVTLRKFTNNFLRKDGVFMLRMISTHAGELMSSELILALW 498          
BLAST of Innexin vs. UniProt/SwissProt
Match: sp|Q19746|INX3_CAEEL (Innexin-3 OS=Caenorhabditis elegans OX=6239 GN=inx-3 PE=1 SV=2)

HSP 1 Score: 161.384 bits (407), Expect = 5.373e-43
Identity = 112/382 (29.32%), Postives = 186/382 (48.69%), Query Frame = 3
Query:  252 LEDLADKMXXXXXXXXXXXXXXXXXXKSYVIKPISCYLSIGPSGGNFQDYIENYCWIHGTIPLYPNQKLSDNHVGWDELERTQKINYYQWVPFILGLQCIMFYIPKLIWQIFCFNQAGTNLDTIIKLSMKMAEIPISERRVENENIAKIIENMLVLHRDFRDSKIANIRRSVYSKCSLFMSSKRLGTMIVFSYFVTKLLYLTNGIGQLFMIQSVLGFYNYLPTFGSHLFWYIVSGTELETQHYFPRVVFCYLKRIRHVGVQNNYVAQCVLPVNMLNEKIYTFLWCWILLVSFATFISIPLWINRLYRADVREHYIGNFLQMLNSYDEHKKPLIHKFINDFLRHDGLFLLRMISNNAGDLIAAYLVNNLWDIYLKKYQ-NRNL 1394
             +D  D++S + +  +L+    +V+ K YV   I C++ +   GG ++ Y E+YC+I  T  +    ++     G  E  +  +I YYQWVP +L +Q  MFY+P  IW    + Q G +  ++I  +  +       R  ++E   K +  ++    D  D++  N     Y +   +   K LG+M    Y   KL+YL N   Q  ++   LG   +L  +G H F  + +G E +    FPRV  C    +R +   + Y  QCVL +NM NEKIY F+W W + V   TFI+    I RL     R +YI + L    +  + +K +I  F N+ L+ DG+ L+R I ++AG ++   +   L+  + +  Q NR+ 
Sbjct:   20 FDDAVDRLSYVTTATLLAFFSIMVSCKQYVGSAIQCWMPMEFKGG-WEQYAEDYCFIQNTFFIPERSEIP----GDVEDRQKAEIGYYQWVPIVLAIQAFMFYLPSWIWSSL-YKQCGLDFPSVISEAEAL-------RSQDSETRTKGVNKLVDFIGDILDTRSKN----EYGRFYCYRFGKGLGSMTSMLYICIKLMYLANVFVQFIILNKFLGNETFL--WGFHTFADLYAGREWQDSGVFPRVTLCDFS-VRKLANVHRYTVQCVLMINMFNEKIYLFIWFWFVFVLITTFINTLCTIYRLSFDSSRHNYIRSLLSGPVNNFKDEKAMIASFANNGLKQDGVLLMRFIDDHAGAMVTKEICEELFKKHGENLQHNRDF 381          
BLAST of Innexin vs. TrEMBL
Match: A0A564YPR7 (Innexin OS=Hymenolepis diminuta OX=6216 GN=inx PE=3 SV=1)

HSP 1 Score: 404.445 bits (1038), Expect = 8.988e-134
Identity = 189/405 (46.67%), Postives = 279/405 (68.89%), Query Frame = 3
Query:  192 MVANEFFSLINRLNAVHNYGLEDLADKMXXXXXXXXXXXXXXXXXXKSYVIKPISCYLSIGPSGGNFQDYIENYCWIHGTIPLYPNQKLSDNHVGWDELERTQKINYYQWVPFILGLQCIMFYIPKLIWQIFCFNQAGTNLDTIIKLSMKMAEIPISERRVENENIAKIIENMLVLHRDFRDSKIANIRRSVYSKCSLFMSSKRLGTMIVFSYFVTKLLYLTNGIGQLFMIQSVLGFYNYLPTFGSHLFWYIVSGTELETQHYFPRVVFCYLKRIRHVGVQNNYVAQCVLPVNMLNEKIYTFLWCWILLVSFATFISIPLWINRLYRADVREHYIGNFLQMLNSYDEHKKPLIHKFINDFLRHDGLFLLRMISNNAGDLIAAYLVNNLWDIYLKKYQNRNLRKDI 1406
            MV  EF   + +L      GLED ADKMS ++SVLIL +C +I+ +K Y++  I+CY+   PSG +F  +++N+CW+HGTIPL   + +  N   WDE ++  +INYYQWVPF+LGLQCI+FYIP++IWQI C+N+ GT+L+ +I ++ K +     +R+   +++A  +  ML  HRD+R  ++A+ RR  +  C +F++SKRLGT ++F+Y   K +YL N IGQL+++Q+ LGF   +  FG  +  Y+++G + +    FPRV FCY++ +RH+G  N YVAQCVLPVNMLNEK+Y FLW W  +V+F T +SIPLWI RL R   +EH+I  FL++   Y+   + ++H F +DFLRHDG+FLLRMIS NAGD++ A ++  +WDIY  K++NR +  DI
Sbjct:    1 MVGVEFIDYLTKLRVNDFLGLEDFADKMSFMYSVLILLLCTTIIAVKQYLLASIACYIPTVPSGKDFDKFLQNFCWVHGTIPLLEGEHIPQNFSEWDEADKNLRINYYQWVPFMLGLQCILFYIPRVIWQIICYNRTGTDLENLISIANKASNTIEGDRQSLVKHVAGTMAEMLFQHRDYRVGRVADARRKAFKFCGVFVASKRLGTWLIFTYLFIKCIYLANAIGQLYLMQTFLGFNKSMTNFGYEVAKYMINGKDWDETRIFPRVSFCYVEHVRHLGTTNRYVAQCVLPVNMLNEKLYIFLWFWTAIVAFCTAVSIPLWIMRLGRQKNKEHFIKKFLRLQEIYNTKDREILHNFTSDFLRHDGVFLLRMISMNAGDVVTADVIVKMWDIYKTKFKNRIMLNDI 405          
BLAST of Innexin vs. TrEMBL
Match: Q2L6M6 (Innexin OS=Dugesia japonica OX=6161 GN=inx9 PE=2 SV=1)

HSP 1 Score: 397.127 bits (1019), Expect = 9.147e-131
Identity = 188/401 (46.88%), Postives = 270/401 (67.33%), Query Frame = 3
Query:  192 MVANEFFSLINRLNAVHNYGLEDLADKMXXXXXXXXXXXXXXXXXXKSYVIKPISCYLSIGPSGGNFQDYIENYCWIHGTIPLYPNQKLSDNHVGWDELERTQKINYYQWVPFILGLQCIMFYIPKLIWQIFCFNQAGTNLDTIIKLSMKMAEIPISERRVENENIAKIIENMLVLHRDFRDSKIANIRRSVYSKCSLFMSSKRLGTMIVFSYFVTKLLYLTNGIGQLFMIQSVLGFYNYLPTFGSHLFWYIVSGTELETQHYFPRVVFCYLKRIRHVGVQNNYVAQCVLPVNMLNEKIYTFLWCWILLVSFATFISIPLWINRLYRADVREHYIGNFLQMLNSYDEHKKPLIHKFINDFLRHDGLFLLRMISNNAGDLIAAYLVNNLWDIYLKKYQNRNL 1394
            MVA EF SL+ +       G+ED ADK++ +FSV+IL + + +VT+KSY  KP++CY++  PSG NF +Y+ENYCW+HGTI + P + +      W  +++T++I YYQWVPFILGLQCIMFY+P++IWQ+ C+N+ GTNL+++   +   +  P SER+ + E I + IE+ML  HRD+R  K+A++RR++Y  C+  + SK +GT +V SY + K +Y  N IGQLF+++  LGF + + +FG  +   I  G E      FPRV +CY+  I+H+G  N YV QC LP+NMLNEKIY FLW W+ LV   T ISIP+W  R+     R  +I  FL M  +Y+   K LI+ FI +FLRHDG+FL+RMI  NAGD++ A +VN LW+IY + Y+N + 
Sbjct:    1 MVAQEFLSLVGQFKLTSYVGVEDFADKLNFLFSVVILIISMMVVTVKSYFFKPLACYIATTPSGSNFDNYLENYCWVHGTISILPGENIPQTDADWAIVDQTKRITYYQWVPFILGLQCIMFYVPRVIWQLICYNKVGTNLESLAIDADAASHSPPSERKDKIERIVRTIEDMLFQHRDYRQGKMADMRRNIYKMCNFCVFSKHMGTWLVLSYILMKFMYGINVIGQLFLMKKFLGFNSSMSSFGYTILSNIADGKEWHQTGIFPRVTYCYIGEIKHLGASNKYVGQCALPINMLNEKIYVFLWFWVFLVGIITAISIPMWFFRIAILSRRSSFIKKFLMMHQAYNRSDKQLINSFIREFLRHDGVFLIRMICINAGDIVTADIVNRLWEIYKENYKNMDF 401          
BLAST of Innexin vs. TrEMBL
Match: Q2L6M7 (Innexin OS=Dugesia japonica OX=6161 GN=inx8 PE=2 SV=1)

HSP 1 Score: 395.971 bits (1016), Expect = 2.059e-130
Identity = 192/402 (47.76%), Postives = 273/402 (67.91%), Query Frame = 3
Query:  192 MVANEFFSLINRLNAVHNYGLEDLADKMXXXXXXXXXXXXXXXXXXKSYVIKPISCYLSIGPSGGNFQDYIENYCWIHGTIPLYPNQKLSDNHVGWDELERTQKINYYQWVPFILGLQCIMFYIPKLIWQIFCFNQAGTNLDTIIKLSMKMAEIPISERRVENENIAKIIENMLVLHRDFRDSKIANIRRSVYSKCSLFMSSKRLGTMIVFSYFVTKLLYLTNGIGQLFMIQSVLGFYNYLPTFGSHLFWYIVSGTELETQHYFPRVVFCYLKRIRHVGVQNNYVAQCVLPVNMLNEKIYTFLWCWILLVSFATFISIPLWINRLYRADVREHYIGNFLQMLNSYDEHKKPLIHKFINDFLRHDGLFLLRMISNNAGDLIAAYLVNNLWDIYLKKYQNRNLR 1397
            MVA EFFSL++        G+ED ADKM+ +FSV+++ + + +VT+KSY  KP+SCY++  PSG  F +YIENYCW+HGTIP+ P + +      W E +  ++I YYQWVPFILGLQCIMFY PK+IWQI C+N+ GTNL+ ++  + + ++ P  +R+   + I++ IE+ML  HRD+R  KIAN RR++YS+C+  + SK LGT +V SYF  K+LY  N IGQL++++S LGF N L  FG  +   +++G E      FPRV +CY   IRH+G  N YV+QC LP+NMLNEKIY FLW W+LLV   T ISI  W+ ++     R  +I   L+M  SY    + L+++FI ++LRHDG+FL+RMI  NAGD++ A ++  LW+IY +KY + + R
Sbjct:    1 MVAEEFFSLLSEFKVSSYVGVEDFADKMNFMFSVVLIILSMMVVTVKSYFFKPLSCYIATTPSGSGFDNYIENYCWVHGTIPILPGENIPQKTNEWAEWDANKRITYYQWVPFILGLQCIMFYTPKIIWQIICYNKIGTNLENLVNGAEEASKSPPEDRKALLDRISRTIEDMLYQHRDYRQGKIANTRRALYSRCNFLVFSKHLGTWLVLSYFFIKVLYGINVIGQLYLMKSFLGFDNSLTYFGYTILENMLNGKEWHQTGIFPRVSYCYNADIRHLGSTNAYVSQCTLPINMLNEKIYVFLWFWVLLVGIITLISIISWLIKMVFLSKRSSFIKKLLKMHQSYKRTDQLLVNQFIKEYLRHDGVFLIRMICINAGDIVTAEILGTLWEIYKEKYIDSDFR 402          
BLAST of Innexin vs. TrEMBL
Match: W6UMB0 (Innexin OS=Echinococcus granulosus OX=6210 GN=inx PE=3 SV=1)

HSP 1 Score: 398.282 bits (1022), Expect = 2.102e-130
Identity = 187/405 (46.17%), Postives = 279/405 (68.89%), Query Frame = 3
Query:  192 MVANEFFSLINRLNAVHNYGLEDLADKMXXXXXXXXXXXXXXXXXXKSYVIKPISCYLSIGPSGGNFQDYIENYCWIHGTIPLYPNQKLSDNHVGWDELERTQKINYYQWVPFILGLQCIMFYIPKLIWQIFCFNQAGTNLDTIIKLSMKMAEIPISERRVENENIAKIIENMLVLHRDFRDSKIANIRRSVYSKCSLFMSSKRLGTMIVFSYFVTKLLYLTNGIGQLFMIQSVLGFYNYLPTFGSHLFWYIVSGTELETQHYFPRVVFCYLKRIRHVGVQNNYVAQCVLPVNMLNEKIYTFLWCWILLVSFATFISIPLWINRLYRADVREHYIGNFLQMLNSYDEHKKPLIHKFINDFLRHDGLFLLRMISNNAGDLIAAYLVNNLWDIYLKKYQNRNLRKDI 1406
            MV  EF   + +L+     GLED ADKMS ++SVLIL +C +I+ +K Y++  I+CY+   PSG +F+ +++N+CW+HGTIP+   + +  N+  W + +   +INYYQWVPF+LGLQCI+FY+P+++WQI C+N+ GT+L+ +I ++ K +    ++R++  +++A  +  ML  HRD+R  K+A+ RR  +    +F++SKRLGT ++F+Y   K +YL N IGQL+++Q+ LGF   +  FG  +  Y+V+G + +    FPRV FCYL+ +RH+G  N YVAQCVLPVNMLNEK+Y FLW W  +V+  T +SIPLWI RL R   + H+I  FL++ + Y    K ++  FI+DFLRHDG+FLLRMIS NAGD++ A +V  +WDIY  KY+NR +  DI
Sbjct:   61 MVGIEFIDYLTKLHVSDFLGLEDFADKMSFMYSVLILLLCTTIIAVKQYLLASIACYIPTVPSGKDFEKFLQNFCWVHGTIPILEGEHIPQNYSEWHDADENMRINYYQWVPFMLGLQCILFYVPRVVWQIICYNRTGTDLENLIAVANKASNTIENDRKMLVKHVAGTMAEMLFQHRDYRRGKVADARRKAFKFFGMFIASKRLGTWLIFTYLFIKCIYLANAIGQLYLMQTFLGFNKSMSNFGYEVARYMVNGRDWDETRIFPRVSFCYLEHVRHLGTTNRYVAQCVLPVNMLNEKLYIFLWFWTAIVAVCTAVSIPLWIMRLGREKNKVHFIKKFLRLQDIYTPEHKEILRNFISDFLRHDGVFLLRMISMNAGDVVTADVVVEMWDIYKTKYKNRAMLNDI 465          
BLAST of Innexin vs. TrEMBL
Match: A0A068WGF5 (Innexin OS=Echinococcus granulosus OX=6210 GN=inx PE=3 SV=1)

HSP 1 Score: 397.512 bits (1020), Expect = 2.114e-130
Identity = 187/405 (46.17%), Postives = 279/405 (68.89%), Query Frame = 3
Query:  192 MVANEFFSLINRLNAVHNYGLEDLADKMXXXXXXXXXXXXXXXXXXKSYVIKPISCYLSIGPSGGNFQDYIENYCWIHGTIPLYPNQKLSDNHVGWDELERTQKINYYQWVPFILGLQCIMFYIPKLIWQIFCFNQAGTNLDTIIKLSMKMAEIPISERRVENENIAKIIENMLVLHRDFRDSKIANIRRSVYSKCSLFMSSKRLGTMIVFSYFVTKLLYLTNGIGQLFMIQSVLGFYNYLPTFGSHLFWYIVSGTELETQHYFPRVVFCYLKRIRHVGVQNNYVAQCVLPVNMLNEKIYTFLWCWILLVSFATFISIPLWINRLYRADVREHYIGNFLQMLNSYDEHKKPLIHKFINDFLRHDGLFLLRMISNNAGDLIAAYLVNNLWDIYLKKYQNRNLRKDI 1406
            MV  EF   + +L+     GLED ADKMS ++SVLIL +C +I+ +K Y++  I+CY+   PSG +F+ +++N+CW+HGTIP+   + +  N+  W + +   +INYYQWVPF+LGLQCI+FY+P+++WQI C+N+ GT+L+ +I ++ K +    ++R++  +++A  +  ML  HRD+R  K+A+ RR  +    +F++SKRLGT ++F+Y   K +YL N IGQL+++Q+ LGF   +  FG  +  Y+V+G + +    FPRV FCYL+ +RH+G  N YVAQCVLPVNMLNEK+Y FLW W  +V+  T +SIPLWI RL R   + H+I  FL++ + Y    K ++  FI+DFLRHDG+FLLRMIS NAGD++ A +V  +WDIY  KY+NR +  DI
Sbjct:    1 MVGIEFIDYLTKLHVSDFLGLEDFADKMSFMYSVLILLLCTTIIAVKQYLLASIACYIPTVPSGKDFEKFLQNFCWVHGTIPILEGEHIPQNYSEWHDADENMRINYYQWVPFMLGLQCILFYVPRVVWQIICYNRTGTDLENLIAVANKASNTIENDRKMLVKHVAGTMAEMLFQHRDYRRGKVADARRKAFKFFGMFIASKRLGTWLIFTYLFIKCIYLANAIGQLYLMQTFLGFNKSMSNFGYEVARYMVNGRDWDETRIFPRVSFCYLEHVRHLGTTNRYVAQCVLPVNMLNEKLYIFLWFWTAIVAVCTAVSIPLWIMRLGREKNKVHFIKKFLRLQDIYTPEHKEILRNFISDFLRHDGVFLLRMISMNAGDVVTADVVVEMWDIYKTKYKNRAMLNDI 405          
BLAST of Innexin vs. Planmine SMEST
Match: SMESG000053975.1 (SMESG000053975.1)

HSP 1 Score: 828.935 bits (2140), Expect = 0.000e+0
Identity = 437/437 (100.00%), Postives = 437/437 (100.00%), Query Frame = 3
Query:  192 MVANEFFSLINRLNAVHNYGLEDLADKMXXXXXXXXXXXXXXXXXXKSYVIKPISCYLSIGPSGGNFQDYIENYCWIHGTIPLYPNQKLSDNHVGWDELERTQKINYYQWVPFILGLQCIMFYIPKLIWQIFCFNQAGTNLDTIIKLSMKMAEIPISERRVENENIAKIIENMLVLHRDFRDSKIANIRRSVYSKCSLFMSSKRLGTMIVFSYFVTKLLYLTNGIGQLFMIQSVLGFYNYLPTFGSHLFWYIVSGTELETQHYFPRVVFCYLKRIRHVGVQNNYVAQCVLPVNMLNEKIYTFLWCWILLVSFATFISIPLWINRLYRADVREHYIGNFLQMLNSYDEHKKPLIHKFINDFLRHDGLFLLRMISNNAGDLIAAYLVNNLWDIYLKKYQNRNLRKDIFSVSNHLKEDEAXXXXXXXXXXXXXXPIMNYL 1502
            MVANEFFSLINRLNAVHNYGLEDLADKMSSIFSVLILSVCVSIVTIKSYVIKPISCYLSIGPSGGNFQDYIENYCWIHGTIPLYPNQKLSDNHVGWDELERTQKINYYQWVPFILGLQCIMFYIPKLIWQIFCFNQAGTNLDTIIKLSMKMAEIPISERRVENENIAKIIENMLVLHRDFRDSKIANIRRSVYSKCSLFMSSKRLGTMIVFSYFVTKLLYLTNGIGQLFMIQSVLGFYNYLPTFGSHLFWYIVSGTELETQHYFPRVVFCYLKRIRHVGVQNNYVAQCVLPVNMLNEKIYTFLWCWILLVSFATFISIPLWINRLYRADVREHYIGNFLQMLNSYDEHKKPLIHKFINDFLRHDGLFLLRMISNNAGDLIAAYLVNNLWDIYLKKYQNRNLRKDIFSVSNHLKEDEANNSTSNSQNLNQCSPIMNYL
Sbjct:    1 MVANEFFSLINRLNAVHNYGLEDLADKMSSIFSVLILSVCVSIVTIKSYVIKPISCYLSIGPSGGNFQDYIENYCWIHGTIPLYPNQKLSDNHVGWDELERTQKINYYQWVPFILGLQCIMFYIPKLIWQIFCFNQAGTNLDTIIKLSMKMAEIPISERRVENENIAKIIENMLVLHRDFRDSKIANIRRSVYSKCSLFMSSKRLGTMIVFSYFVTKLLYLTNGIGQLFMIQSVLGFYNYLPTFGSHLFWYIVSGTELETQHYFPRVVFCYLKRIRHVGVQNNYVAQCVLPVNMLNEKIYTFLWCWILLVSFATFISIPLWINRLYRADVREHYIGNFLQMLNSYDEHKKPLIHKFINDFLRHDGLFLLRMISNNAGDLIAAYLVNNLWDIYLKKYQNRNLRKDIFSVSNHLKEDEANNSTSNSQNLNQCSPIMNYL 437          
BLAST of Innexin vs. Planmine SMEST
Match: SMESG000080788.1 (SMESG000080788.1)

HSP 1 Score: 404.831 bits (1039), Expect = 1.972e-137
Identity = 198/402 (49.25%), Postives = 272/402 (67.66%), Query Frame = 3
Query:  192 MVANEFFSLINRLNAVHNYGLEDLADKMXXXXXXXXXXXXXXXXXXKSYVIKPISCYLSIGPSGGNFQDYIENYCWIHGTIPLYPNQKLSDNHVGWDELERTQKINYYQWVPFILGLQCIMFYIPKLIWQIFCFNQAGTNLDTIIKLSMKMAEIPISERRVENENIAKIIENMLVLHRDFRDSKIANIRRSVYSKCSLFMSSKRLGTMIVFSYFVTKLLYLTNGIGQLFMIQSVLGFYNYLPTFGSHLFWYIVSGTELETQHYFPRVVFCYLKRIRHVGVQNNYVAQCVLPVNMLNEKIYTFLWCWILLVSFATFISIPLWINRLYRADVREHYIGNFLQMLNSYDEHKKPLIHKFINDFLRHDGLFLLRMISNNAGDLIAAYLVNNLWDIYLKKYQNRNLR 1397
            MVA EF +LI +       G+ED ADK+S +FSV +L + + +VTIKSY+ KP++CY +  P G NF++Y+ENYCW+HGTI   P + +  N V W   + T++INYYQWVPFILGLQC MFYIPK+IWQI C+N++GTNL++I+  +      P  ER+ + E IA+ IE+ML  HRD+R    A +RR +Y+ C+  + SK +GT ++ SY + K LY  N IGQLF+++  LGF N   +FG  +   ++SG E      FPRV +CY++ I+HVGV N YVAQC LPVNMLNEKIY FLW W++LV   T ISIPLW  R+     R  +I  FL M  +Y+   KP+I+ FI +FLRHDG+FL+RM+  NAGD+I A +VN L +IY + Y++ + R
Sbjct:    1 MVAEEFLNLIGQFKISTYVGIEDFADKLSFLFSVTLLILSMMVVTIKSYLFKPLACYTATAPGGSNFENYLENYCWVHGTITFLPGEDIPQNDVDWARADDTRRINYYQWVPFILGLQCFMFYIPKIIWQIICYNKSGTNLESIVNDANAANNTPPVERKDKIERIARTIEDMLFQHRDYRQGNFAKLRRKIYNTCNFCVFSKHMGTWLILSYILIKFLYGLNVIGQLFIMKKFLGFNNSTSSFGYTVLSNMISGKEWHQTGIFPRVTYCYVRNIKHVGVANKYVAQCALPVNMLNEKIYVFLWFWMVLVGIVTAISIPLWFYRMAFLSRRSKFIKRFLMMHQNYERSDKPMINNFIEEFLRHDGVFLVRMLFINAGDIITADIVNRLLEIYKENYKHLDFR 402          
BLAST of Innexin vs. Planmine SMEST
Match: SMESG000065083.1 (SMESG000065083.1)

HSP 1 Score: 347.821 bits (891), Expect = 4.164e-115
Identity = 191/407 (46.93%), Postives = 260/407 (63.88%), Query Frame = 3
Query:  192 MVANEFFSLINRLNAVHNYGLEDLADKMXXXXXXXXXXXXXXXXXXKSYVIKPISCYLSIGPSGGNFQDYIENYCWIHGTIPLYPNQKLSDNHVGWDELERTQKINYYQWVPFILGLQCIMFYIPKLIWQIFCFNQAGTNLDTIIKLSMKMAEIPISERRVENENIAKIIENMLVLHRDFRDSKIANIRRSVYSKCSLFMSSKRLGTMIVFSYFVTKLLYLTNGIGQLFMIQSVLGFYNY-LPTFGSHLFWYIVSGTELETQHYFPRVVFCYLKRIRHVGVQNNYVAQCVLPVNMLNEKIYTFLWCWILLVSFATFISIPLWINRLYRADVREHYIGNFLQMLN--SYDEHKKPLIHKFINDFLRHDGLFLLRMISNNAGDLIAAYLVNNLWDIYLKKYQNRNLRKD 1403
            MVA+EF   +++L    N GLEDL D+++  FSV++L VC+ IVT+K YV KPISCYL     G N   Y+EN CW+ GTI L    K       W  LE+  K+ YYQWVPF+LGLQCIMFY+PKL+WQI C+N+ GT++  ++  + +        R      ++K +E +L  HRD R  K+A  RR +++     M SKR+GT +V SY + KL Y+ NG  QL ++Q  LGF ++ L TFG  +   I SGT+ +T   FPRV +C++K + H+GV N+ VAQCVLPVNMLNE+IY FLWCWIL+V   T +SIP+WI R+     R H+I  FL +    + D+ +  L+ KF + FLRHDG+FLL+MIS NAGD+I + +V  LW+IY   Y NRN   D
Sbjct:    1 MVASEFLDYLSKLQVSTNVGLEDLPDRLNFTFSVIVLMVCILIVTVKQYVFKPISCYLPNNIGGSNLLSYVENLCWVQGTIALSNQAKFPSTDEEWKNLEK-HKMLYYQWVPFMLGLQCIMFYVPKLVWQIICYNRTGTDIQHLVVSANQAVHSSDEARSKMVSYLSKTLEQLLYQHRDHRSGKLAKFRRKIHNSVGFLMCSKRIGTWLVSSYLLLKLSYVANGFIQLIIMQKFLGFSDFNLLTFGIEVGNNIWSGTDWKTTLIFPRVSYCFVK-VTHLGVINSMVAQCVLPVNMLNERIYFFLWCWILIVLSLTILSIPIWILRILCIKYRRHFIRQFLIISEEITKDQKENYLLAKFESQFLRHDGIFLLKMISLNAGDIITSEIVCQLWNIYKTNYVNRNFLND 405          
BLAST of Innexin vs. Planmine SMEST
Match: SMESG000066858.1 (SMESG000066858.1)

HSP 1 Score: 332.028 bits (850), Expect = 5.308e-109
Identity = 176/407 (43.24%), Postives = 251/407 (61.67%), Query Frame = 3
Query:  192 MVANEFFSLINRLNAVHNYGLEDLADKMXXXXXXXXXXXXXXXXXXKSYVIKPISCYLSIGPSGGNFQDYIENYCWIHGTIPLYPNQKLSDNHVGWD-ELERT-QKINYYQWVPFILGLQCIMFYIPKLIWQIFCFNQAGTNLDTIIKLSMKMAEIPISERRVENENIAKIIENMLVLHRDFRDSKIANIRRSVYSKCSLFMSSKRLGTMIVFSYFVTKLLYLTNGIGQLFMIQSVLGFY-NYLPTFGSHLFWYIVSGTELETQHYFPRVVFCYLKRIRHVGVQNNYVAQCVLPVNMLNEKIYTFLWCWILLVSFATFISIPLWINRLYRADVREHYIGNFLQMLNSYDEHKKPLIHKFINDFLRHDGLFLLRMISNNAGDLIAAYLVNNLWDIYLKKYQNRNLRKD 1403
            MVAN    LI         GLED+ DK+S   SV+I  +C  IVT K+Y++KP+SCY +I P+G NF  Y+ NYCWI GT+P  P  K     VG D +L+ + +KINYYQWVPF+L LQCIMFY+P+L WQ+  +N+ G +L+ I K +   +    + R+ + + IAK + N+   HRD++    AN RR ++   S FM SKRLGT + + YFV KL++L N +GQL++IQ  LGF+ N +       F  +V+G +  T   FPRV  C +  I+ +GV+NNY+ QCVL  NMLNEKIY FLW W+ +V   T I+I LW  ++     R  +I  FL+    Y + K+  +  FI  FLRHDG F++ M++ N GDLI +++V+ LW+IY  +Y N +   +
Sbjct:    1 MVANTLLDLIKSHKVTDYQGLEDIGDKISFQISVIIYIICGFIVTSKTYILKPLSCYTAISPTGSNFDGYLRNYCWITGTVPWVPGDKFP--QVGDDMKLDDSLKKINYYQWVPFVLALQCIMFYLPRLFWQLMSYNKIGIDLELIFKDASSASNDDEAARKKKAKGIAKNLANVFFFHRDYKYGTWANFRRKIFKFASFFMMSKRLGTWLTYWYFVMKLMFLANAVGQLYLIQRFLGFHGNNIFETSRVFFDSLVNGVQWTTSRLFPRVTVCSIDNIKLLGVENNYITQCVLSQNMLNEKIYMFLWFWLHIVIVVTLITIGLWCKKIIFLGSRAEFIKKFLKNHEVYRKSKRDSLDNFIQTFLRHDGSFIIMMMTMNCGDLITSHVVSELWEIYQSEYANSDTSSE 405          
BLAST of Innexin vs. Planmine SMEST
Match: SMESG000066886.1 (SMESG000066886.1)

HSP 1 Score: 332.028 bits (850), Expect = 5.365e-109
Identity = 176/407 (43.24%), Postives = 252/407 (61.92%), Query Frame = 3
Query:  192 MVANEFFSLINRLNAVHNYGLEDLADKMXXXXXXXXXXXXXXXXXXKSYVIKPISCYLSIGPSGGNFQDYIENYCWIHGTIPLYPNQKLSDNHVGWD-ELERT-QKINYYQWVPFILGLQCIMFYIPKLIWQIFCFNQAGTNLDTIIKLSMKMAEIPISERRVENENIAKIIENMLVLHRDFRDSKIANIRRSVYSKCSLFMSSKRLGTMIVFSYFVTKLLYLTNGIGQLFMIQSVLGFYNYLPTFGSHLFW-YIVSGTELETQHYFPRVVFCYLKRIRHVGVQNNYVAQCVLPVNMLNEKIYTFLWCWILLVSFATFISIPLWINRLYRADVREHYIGNFLQMLNSYDEHKKPLIHKFINDFLRHDGLFLLRMISNNAGDLIAAYLVNNLWDIYLKKYQNRNLRKD 1403
            MVAN    LI         GLED+ DK+S   SV+I  +C  IVT K+Y++KP+SCY +I P+G NF  Y+ NYCWI GT+P  P  K     VG D +L+ + +KINYYQWVPF+L LQCIMFY+P+L WQ+  +N+ G +L+ I K +   +    + R+ + + IAK + N+   HRD++    AN RR ++   S FM SKRLGT + + YFV KL++L N +GQL++IQ  LGF+       S +F+  +V+G +  T   FPRV  C +  I+ +GV+NNY+ QCVL  NMLNEKIY FLW W+ +V   T I+I LW  ++     R  +I  FL+    Y + K+  +  FI  FLRHDG F++ M++ N GDLI +++V+ LW+IY  +Y N +   +
Sbjct:    1 MVANTLLDLIKSHKVTDYQGLEDIGDKISFQISVIIYIICGFIVTSKTYILKPLSCYTAISPTGSNFDGYLRNYCWITGTVPWVPGDKFP--QVGDDMKLDDSLKKINYYQWVPFVLALQCIMFYLPRLFWQLMSYNKIGIDLELIFKDASSASNDDEAARKKKAKGIAKNLANVFFFHRDYKYGTWANFRRKIFKFASFFMMSKRLGTWLTYWYFVMKLMFLANAVGQLYLIQRFLGFHGNNIFETSRIFFDSLVNGVQWTTSRLFPRVTVCSIDNIKLLGVENNYITQCVLSQNMLNEKIYMFLWFWLHIVIVVTLITIGLWCKKIIFLGSRAEFIKKFLKNHEVYRKSKRDSLDNFIQTFLRHDGSFIIMMMTMNCGDLITSHVVSELWEIYQSEYANSDTSSE 405          
The following BLAST results are available for this feature:
BLAST of Innexin vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Innexin vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
inx-131.106e-5328.50Innexin [Source:UniProtKB/TrEMBL;Acc:O44887][more]
inx-184.953e-5331.28Innexin [Source:UniProtKB/TrEMBL;Acc:Q8MXG8][more]
inx-184.953e-5331.28Innexin [Source:UniProtKB/TrEMBL;Acc:Q8MXG8][more]
inx-195.804e-5332.09Innexin-19 [Source:UniProtKB/Swiss-Prot;Acc:O6171... [more]
inx-186.968e-5331.28Innexin [Source:UniProtKB/TrEMBL;Acc:Q8MXG8][more]
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BLAST of Innexin vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Inx26.183e-1927.40gene:FBgn0027108 transcript:FBtr0301860[more]
Inx26.183e-1927.40gene:FBgn0027108 transcript:FBtr0071005[more]
Inx26.183e-1927.40gene:FBgn0027108 transcript:FBtr0332314[more]
Inx26.183e-1927.40gene:FBgn0027108 transcript:FBtr0071006[more]
Inx32.746e-1525.63gene:FBgn0265274 transcript:FBtr0085350[more]
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BLAST of Innexin vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Innexin vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Innexin vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Innexin vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|A8WVX4|INX19_CAEBR3.181e-5332.33Innexin-19 OS=Caenorhabditis briggsae OX=6238 GN=i... [more]
sp|O61715|INX19_CAEEL9.363e-5232.09Innexin-19 OS=Caenorhabditis elegans OX=6239 GN=in... [more]
sp|O01393|UNC9_CAEEL2.267e-5029.55Innexin unc-9 OS=Caenorhabditis elegans OX=6239 GN... [more]
sp|Q03412|UNC7_CAEEL5.403e-4429.70Innexin unc-7 OS=Caenorhabditis elegans OX=6239 GN... [more]
sp|Q19746|INX3_CAEEL5.373e-4329.32Innexin-3 OS=Caenorhabditis elegans OX=6239 GN=inx... [more]
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BLAST of Innexin vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A564YPR78.988e-13446.67Innexin OS=Hymenolepis diminuta OX=6216 GN=inx PE=... [more]
Q2L6M69.147e-13146.88Innexin OS=Dugesia japonica OX=6161 GN=inx9 PE=2 S... [more]
Q2L6M72.059e-13047.76Innexin OS=Dugesia japonica OX=6161 GN=inx8 PE=2 S... [more]
W6UMB02.102e-13046.17Innexin OS=Echinococcus granulosus OX=6210 GN=inx ... [more]
A0A068WGF52.114e-13046.17Innexin OS=Echinococcus granulosus OX=6210 GN=inx ... [more]
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BLAST of Innexin vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Innexin vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Innexin vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Innexin vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Innexin vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Innexin vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000053975.10.000e+0100.00SMESG000053975.1[more]
SMESG000080788.11.972e-13749.25SMESG000080788.1[more]
SMESG000065083.14.164e-11546.93SMESG000065083.1[more]
SMESG000066858.15.308e-10943.24SMESG000066858.1[more]
SMESG000066886.15.365e-10943.24SMESG000066886.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30028531 ID=SMED30028531|Name=Innexin|organism=Schmidtea mediterranea sexual|type=transcript|length=1571bp
GAGATGTTCGATTATAAAATAATCCAAATTATTAAGGATTATTTGATAAA
AGGTATTTTATAATTGAAAATTTTACATTTAATATATCTTTTGCAAGAGC
TTGTCATATTATTTACTTGTATGAAATTTTAATTTATCATGCTATTAAGA
AATCACCGTTTTATTATTATAAATGTTTCATATTTCAGTAAATGGTGGCT
AATGAATTTTTTAGTCTTATAAATCGACTTAATGCTGTCCACAATTATGG
ACTGGAAGACTTGGCAGATAAAATGAGTTCCATTTTTAGTGTACTTATTC
TCTCAGTATGCGTTTCCATTGTGACAATTAAGTCATACGTTATCAAACCC
ATCTCCTGCTATTTAAGCATAGGGCCTTCTGGAGGGAACTTCCAGGATTA
TATAGAAAATTATTGCTGGATTCATGGCACCATTCCACTGTATCCGAATC
AAAAGTTATCTGATAATCATGTAGGATGGGACGAGTTGGAAAGAACTCAA
AAAATAAATTATTATCAATGGGTCCCTTTTATCCTCGGTTTGCAGTGTAT
TATGTTTTATATACCAAAATTAATTTGGCAGATCTTTTGTTTCAATCAAG
CTGGAACGAATCTTGACACAATAATTAAGTTATCAATGAAAATGGCAGAG
ATACCAATTAGTGAAAGGCGAGTGGAAAACGAGAACATCGCAAAGATTAT
TGAGAATATGCTAGTTCTCCATAGGGATTTCCGAGACAGTAAGATAGCAA
ACATTCGGAGATCCGTATATAGTAAGTGCAGCTTATTCATGAGCAGTAAA
CGATTGGGAACGATGATTGTCTTCTCGTACTTTGTAACCAAATTGTTGTA
CCTAACTAATGGGATCGGGCAGTTGTTTATGATTCAATCCGTTTTGGGAT
TTTATAATTACCTCCCTACCTTTGGATCACATCTATTTTGGTACATTGTA
TCAGGAACTGAATTGGAGACTCAACACTATTTCCCAAGAGTGGTATTTTG
TTATTTAAAAAGAATCCGTCATGTTGGTGTTCAAAATAACTACGTAGCCC
AATGCGTCCTTCCAGTAAATATGTTAAATGAGAAAATTTATACATTTCTG
TGGTGTTGGATCTTACTGGTGTCATTTGCTACATTTATTAGCATACCCCT
CTGGATTAACAGACTGTACCGGGCGGATGTCAGAGAACATTACATTGGTA
ACTTTCTGCAAATGCTGAATTCCTACGATGAACACAAAAAGCCGTTAATA
CACAAGTTTATCAATGACTTTCTCAGGCACGACGGATTGTTTTTGTTGCG
CATGATTTCAAACAATGCCGGAGACTTAATTGCTGCCTATCTGGTGAATA
ATTTGTGGGATATTTACTTAAAAAAATATCAAAACAGAAATCTTAGAAAG
GATATTTTTTCAGTGTCAAATCATTTGAAAGAAGACGAAGCAAATAACTC
AACTTCTAACAGCCAAAATCTTAACCAATGTTCACCTATAATGAATTATC
TGTGATAAGATTTTTGCTAAATTTTACTGTCTTAGATGATTATTTTTTTG
TGATTTTCTGCTGTAATTTAT
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protein sequence of SMED30028531-orf-1

>SMED30028531-orf-1 ID=SMED30028531-orf-1|Name=SMED30028531-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=438bp
MVANEFFSLINRLNAVHNYGLEDLADKMSSIFSVLILSVCVSIVTIKSYV
IKPISCYLSIGPSGGNFQDYIENYCWIHGTIPLYPNQKLSDNHVGWDELE
RTQKINYYQWVPFILGLQCIMFYIPKLIWQIFCFNQAGTNLDTIIKLSMK
MAEIPISERRVENENIAKIIENMLVLHRDFRDSKIANIRRSVYSKCSLFM
SSKRLGTMIVFSYFVTKLLYLTNGIGQLFMIQSVLGFYNYLPTFGSHLFW
YIVSGTELETQHYFPRVVFCYLKRIRHVGVQNNYVAQCVLPVNMLNEKIY
TFLWCWILLVSFATFISIPLWINRLYRADVREHYIGNFLQMLNSYDEHKK
PLIHKFINDFLRHDGLFLLRMISNNAGDLIAAYLVNNLWDIYLKKYQNRN
LRKDIFSVSNHLKEDEANNSTSNSQNLNQCSPIMNYL*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: cellular component
TermDefinition
GO:0005886plasma membrane
GO:0005921gap junction
GO:0016020membrane
GO:0016021integral component of membrane
GO:0030054cell junction
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000026gut
PLANA:0000419prepharyngeal region
Vocabulary: INTERPRO
TermDefinition
IPR000990Innexin
Vocabulary: biological process
TermDefinition
GO:0006810transport
GO:0006811ion transport
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR000990InnexinPRINTSPR01262INNEXINcoord: 45..56
score: 41.33
coord: 288..304
score: 62.12
coord: 263..272
score: 50.0
coord: 213..227
score: 46.67
coord: 107..129
score: 56.35
coord: 74..83
score: 41.6
IPR000990InnexinPFAMPF00876Innexincoord: 22..392
e-value: 3.1E-96
score: 322.7
IPR000990InnexinPANTHERPTHR11893INNEXINcoord: 9..404
IPR000990InnexinPROSITEPS51013PANNEXINcoord: 17..398
score: 29.104
NoneNo IPR availableTMHMMTMhelixcoord: 29..51
NoneNo IPR availableTMHMMTMhelixcoord: 209..231
NoneNo IPR availableTMHMMTMhelixcoord: 300..322