Innexin
Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30028531 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 4
Homology
BLAST of Innexin vs. Ensembl Celegans
Match: inx-13 (Innexin [Source:UniProtKB/TrEMBL;Acc:O44887]) HSP 1 Score: 186.422 bits (472), Expect = 1.106e-53 Identity = 114/400 (28.50%), Postives = 209/400 (52.25%), Query Frame = 3 Query: 228 LNAVHNYGLEDLADKMXXXXXXXXXXXXXXXXXXKSYVIKPISCYLSIGPSGGNFQDYIENYCWIHGTIPLYPNQKLSDNHVGWDELERTQKINYYQWVPFILGLQCIMFYIPKLIWQIFCFNQAGTNLDTIIKLSMKMAEIPISERRVENENIAKIIENMLVLHRDFRDSKIANIRRSVYSKCSLFMSSKRLGTMIVFSYFVTKLLYLTNGIGQLFMIQSVLGFYNYLPTFGSHLFWY------IVSGTELETQHYFPRVVFCYLKRIRHVGVQNNYVAQCVLPVNMLNEKIYTFLWCWILLVSFATFISIPLWINRLYRADVREHYIGNFLQMLNSYDEHKK---PLIHKFINDFLRHDGLFLLRMISNNAGDLIAAYLVNNLWDIYLKKYQNRNLRK 1400 L +H G +D D+++ ++ ++L + ++ K YV +PI C++ +G ++ Y ENYC++ T + P++ + D+ + + E I YYQWVPFILGLQ I+FY+P L W++ FN +G L ++ + K + R ++ + L L F + Y+ + G+ + + Y K LYL + Q ++ + LG S+ FW I++G E E +FPRV C + +R +G ++ + QCVL +NM NEK+Y FLW W+++V ATF+++ W +L R+ +I ++LQ+ +++ + ++ KF++ L+ DG+F+ +I NN G + + ++ ++WD +L+ NR+ +K Sbjct: 8 LKGLHKQGDDDSIDRLNYYWTPMLLVIFALTLSAKQYVGQPIQCWIPAQFTGA-WEQYSENYCFVQNTYFISPDKYIPDSEIDREGAE----IGYYQWVPFILGLQAILFYLPSLFWRLMNFN-SGVALKKMLFGAKKADRVDEKARNEAAKSTGAHLYESLTLQSRF----------AKYTSAFTYG-----GSYLTYLYLFVKFLYLVQIVFQFIILNNFLG--------TSYTFWGLGILSDILNGREWEESGHFPRVTMCDFE-VRVLGNKHRHTVQCVLMINMFNEKVYVFLWFWLVIVGVATFLNLVNWTRKLMFRSARKAHIKSYLQIEDNFSDDNSRNGQILDKFVDYKLKSDGVFITHLIDNNGGSVFSHDVIVDMWDRFLQDEDNRSQKK 377
BLAST of Innexin vs. Ensembl Celegans
Match: inx-18 (Innexin [Source:UniProtKB/TrEMBL;Acc:Q8MXG8]) HSP 1 Score: 185.267 bits (469), Expect = 4.953e-53 Identity = 117/374 (31.28%), Postives = 199/374 (53.21%), Query Frame = 3 Query: 255 EDLADKMXXXXXXXXXXXXXXXXXXKSYVIKPISCYLSIGPSGGNFQDYIENYCWIHGTIPLYPNQKLSDNHVGWDELERTQKINYYQWVPFILGLQCIMFYIPKLIWQIFCFNQAGTNLDTIIKLSMKMAEIPISERRVENENIAKIIENMLVLHRDFRDSKIANIRRSVYSKCSLFMSSKRLGTMIVFSYFVTKLLYLTNGIGQLFMIQSVLGFYNYLPTFGSHLFWYIVSGTELETQHYFPRVVFCYLKRIRHVGVQNNYVAQCVLPVNMLNEKIYTFLWCWILLVSFATFISIPLWINRLYRADVREHYIGNFLQMLNSYDEHKKPLIHKFINDFLRHDGLFLLRMISNNAGDLIAAYLVNNLWDIYLKK 1376 +D D++ +++ ++ + +V+ K YV PI C++ + + Y ENYCW+ T + P Q L + + D+ ER Q I YYQWVPF+L + + F+IP +W++ Q+G N +++L + R + +A+ I++ L+ RD R SVY ++F K G + Y K L+L N I Q ++ S L +Y P FG+H+ + + G E FPRV C + IR +G + + QCVL +NML EKI+ FLW W+ +++ T +++ W L REH++ L + + I +F++ FLR DG+FLL+MI++++G+L+AA + LW I++++ Sbjct: 25 DDFVDRLHYLYTSTMVLMFAVLVSAKQYVGHPIECFVPAQFTRA-MEQYTENYCWVQNTYWV-PFQDLIPHRL--DDRERRQ-IGYYQWVPFVLAVAALTFHIPSSVWRMLA-GQSGLNAGLVLQLVCGDENVDPVVRDKTVDIVARHIDDALMYQRDH-----GARRHSVYI-FAIFKLGKFYGAYVSSVYIFIKALHLANVILQFMLLNSFLQTSDY-PMFGAHVLYDLFMGREWRDSGKFPRVTLCDFE-IRVLGNVHRHTVQCVLVINMLTEKIFIFLWLWLTVLAIVTALNLIFWFIALVSNSCREHFVSKHLDI-------QSDQISRFVHRFLRADGVFLLQMIASHSGNLMAAKVTEQLWMIFVRR 377
BLAST of Innexin vs. Ensembl Celegans
Match: inx-18 (Innexin [Source:UniProtKB/TrEMBL;Acc:Q8MXG8]) HSP 1 Score: 185.267 bits (469), Expect = 4.953e-53 Identity = 117/374 (31.28%), Postives = 199/374 (53.21%), Query Frame = 3 Query: 255 EDLADKMXXXXXXXXXXXXXXXXXXKSYVIKPISCYLSIGPSGGNFQDYIENYCWIHGTIPLYPNQKLSDNHVGWDELERTQKINYYQWVPFILGLQCIMFYIPKLIWQIFCFNQAGTNLDTIIKLSMKMAEIPISERRVENENIAKIIENMLVLHRDFRDSKIANIRRSVYSKCSLFMSSKRLGTMIVFSYFVTKLLYLTNGIGQLFMIQSVLGFYNYLPTFGSHLFWYIVSGTELETQHYFPRVVFCYLKRIRHVGVQNNYVAQCVLPVNMLNEKIYTFLWCWILLVSFATFISIPLWINRLYRADVREHYIGNFLQMLNSYDEHKKPLIHKFINDFLRHDGLFLLRMISNNAGDLIAAYLVNNLWDIYLKK 1376 +D D++ +++ ++ + +V+ K YV PI C++ + + Y ENYCW+ T + P Q L + + D+ ER Q I YYQWVPF+L + + F+IP +W++ Q+G N +++L + R + +A+ I++ L+ RD R SVY ++F K G + Y K L+L N I Q ++ S L +Y P FG+H+ + + G E FPRV C + IR +G + + QCVL +NML EKI+ FLW W+ +++ T +++ W L REH++ L + + I +F++ FLR DG+FLL+MI++++G+L+AA + LW I++++ Sbjct: 25 DDFVDRLHYLYTSTMVLMFAVLVSAKQYVGHPIECFVPAQFTRA-MEQYTENYCWVQNTYWV-PFQDLIPHRL--DDRERRQ-IGYYQWVPFVLAVAALTFHIPSSVWRMLA-GQSGLNAGLVLQLVCGDENVDPVVRDKTVDIVARHIDDALMYQRDH-----GARRHSVYI-FAIFKLGKFYGAYVSSVYIFIKALHLANVILQFMLLNSFLQTSDY-PMFGAHVLYDLFMGREWRDSGKFPRVTLCDFE-IRVLGNVHRHTVQCVLVINMLTEKIFIFLWLWLTVLAIVTALNLIFWFIALVSNSCREHFVSKHLDI-------QSDQISRFVHRFLRADGVFLLQMIASHSGNLMAAKVTEQLWMIFVRR 377
BLAST of Innexin vs. Ensembl Celegans
Match: inx-19 (Innexin-19 [Source:UniProtKB/Swiss-Prot;Acc:O61715]) HSP 1 Score: 186.037 bits (471), Expect = 5.804e-53 Identity = 138/430 (32.09%), Postives = 227/430 (52.79%), Query Frame = 3 Query: 228 LNAVHNYGLEDLADKMXXXXXXXXXXXXXXXXXXKSYVIKPISCYLSIGP-SGGNFQDYIENYCWIHGT--IPLYPNQKLSDNHVGWDELERTQKINYYQWVPFILGLQCIMFYIPKLIWQIFCFNQAGTNLDTIIKLSMK-MAEIPISERRVENENIAK-IIENMLVLHRDFRDSKIANIRRSVYSKCSLFMSSKRLGTMIVFSYFVTKLLYLTNGIGQLFMIQSVLGFYNYLPTFGSHLFWYIVSGTELETQHYFPRVVFCYLKRIRHVGVQNNYVAQCVLPVNMLNEKIYTFLWCWILLVSFATFISIPLWINRLYRADVREHYIGNFLQMLNSYDEHKK---------------------PLIHKFINDFLRHDGLFLLRMISNNAGDLIAAYLVNNLWDIYLKKYQNRNLRKDIFSVSNHLKEDE 1439 +NA+ G +D D+++ ++ LIL+VC +++ K Y PI C+ + P S + ++YIE+YCWI T IP+Y N + D+H +E ++I YYQWVPFIL + +MF +P + W++ C Q+G N+ T+I + A + S+R+ E I ++N+ + + R I R +S+ F+S + L + F TKLLY N + Q ++ + L ++L FG + I +G +FPRV C + +R++ N Y QC L +N++NEK++ FLWCW ++++ T S WI + + Y+ F+Q+ S E KK L+ F++DFL+ DG+ +LRMISN+AGD+I LV NLW ++++ RN R+ F +K+ E Sbjct: 12 INALSVRGDDDAVDRLNYYYTPLILAVCCLVISAKQYGGTPIECW--VNPHSRESMEEYIESYCWIQNTYWIPMYEN--VPDDHTAREE----KQIGYYQWVPFILIAEALMFSLPCIFWRL-CSFQSGLNIQTLINAACDGQALLDASDRQKAVEAITTNFVDNLDLQSPNGRIRARGWIARIKFSR---FLSGQCLSILHSF----TKLLYSMNVVAQFLILNACLKSSDFL-FFGFQVLNDIWAGRPWTETGHFPRVTLCDFE-VRYLANLNRYTVQCALLINIINEKVFAFLWCWYMILAIITTCSFIYWIANSFIHSEKVDYVMKFIQIAES-SEFKKLQKFEKDATVERLYTVIAFAPHLLDTFVSDFLKSDGVLMLRMISNHAGDMIVVQLVRNLW----QEFRERNWRE--FEEHEEMKDVE 416
BLAST of Innexin vs. Ensembl Celegans
Match: inx-18 (Innexin [Source:UniProtKB/TrEMBL;Acc:Q8MXG8]) HSP 1 Score: 185.652 bits (470), Expect = 6.968e-53 Identity = 117/374 (31.28%), Postives = 199/374 (53.21%), Query Frame = 3 Query: 255 EDLADKMXXXXXXXXXXXXXXXXXXKSYVIKPISCYLSIGPSGGNFQDYIENYCWIHGTIPLYPNQKLSDNHVGWDELERTQKINYYQWVPFILGLQCIMFYIPKLIWQIFCFNQAGTNLDTIIKLSMKMAEIPISERRVENENIAKIIENMLVLHRDFRDSKIANIRRSVYSKCSLFMSSKRLGTMIVFSYFVTKLLYLTNGIGQLFMIQSVLGFYNYLPTFGSHLFWYIVSGTELETQHYFPRVVFCYLKRIRHVGVQNNYVAQCVLPVNMLNEKIYTFLWCWILLVSFATFISIPLWINRLYRADVREHYIGNFLQMLNSYDEHKKPLIHKFINDFLRHDGLFLLRMISNNAGDLIAAYLVNNLWDIYLKK 1376 +D D++ +++ ++ + +V+ K YV PI C++ + + Y ENYCW+ T + P Q L + + D+ ER Q I YYQWVPF+L + + F+IP +W++ Q+G N +++L + R + +A+ I++ L+ RD R SVY ++F K G + Y K L+L N I Q ++ S L +Y P FG+H+ + + G E FPRV C + IR +G + + QCVL +NML EKI+ FLW W+ +++ T +++ W L REH++ L + + I +F++ FLR DG+FLL+MI++++G+L+AA + LW I++++ Sbjct: 25 DDFVDRLHYLYTSTMVLMFAVLVSAKQYVGHPIECFVPAQFTRA-MEQYTENYCWVQNTYWV-PFQDLIPHRL--DDRERRQ-IGYYQWVPFVLAVAALTFHIPSSVWRMLA-GQSGLNAGLVLQLVCGDENVDPVVRDKTVDIVARHIDDALMYQRDH-----GARRHSVYI-FAIFKLGKFYGAYVSSVYIFIKALHLANVILQFMLLNSFLQTSDY-PMFGAHVLYDLFMGREWRDSGKFPRVTLCDFE-IRVLGNVHRHTVQCVLVINMLTEKIFIFLWLWLTVLAIVTALNLIFWFIALVSNSCREHFVSKHLDI-------QSDQISRFVHRFLRADGVFLLQMIASHSGNLMAAKVTEQLWMIFVRR 377
BLAST of Innexin vs. Ensembl Fly
Match: Inx2 (gene:FBgn0027108 transcript:FBtr0301860) HSP 1 Score: 88.9669 bits (219), Expect = 6.183e-19 Identity = 80/292 (27.40%), Postives = 127/292 (43.49%), Query Frame = 3 Query: 330 KSYVIKPISCYLSIGPSGGNFQDYIENYCWIHGTIPLYPN----------QKLSDNHV-GWDELERTQKINYYQWVPFILGLQCIMFYIPKLIWQIFCFNQAGTNLDTIIKLSMKMAEI--PISERRVENENIAKIIENMLVLHRDFRDSKIANIRRSVYSKCSLFMSSKRLGTMIVFSYFVTKLLYLTNGIGQLFMIQSVLGFYNYLPTFGSHLFWYIVSGTELETQH-------YFPRVVFCYLKRIRHVGVQNNYVAQCVLPVNMLNEKIYTFLWCWILLVSFATFISI 1145 + Y+ PI C + P G ++ YCWI+ T + Q +HV G DE++ + YYQWV F+L Q I+FY+P+ +W+ + + G +L M + ++ PI +N+ + +LV D I N+ R F +FV + L N IGQ++ + L T+GS + + TELE FP+V C + G + CVLP+N++NEKIY FLW W +++S + IS+ Sbjct: 45 RQYIGDPIDCIVDEIPLG-----VMDTYCWIYSTFTVPERLTGITGRDVVQPGVGSHVEGEDEVKYHK---YYQWVCFVLFFQAILFYVPRYLWKSW---EGG-------RLKMLVMDLNSPIVNDECKNDR-----KKILV------DYFIGNLNRH---------------NFYAFRFFVCEALNFVNVIGQIYFVDFFLD--GEFSTYGSDVLKF----TELEPDERIDPMARVFPKVTKCTFHKYGPSGSVQTHDGLCVLPLNIVNEKIYVFLWFWFIILSIMSGISL 286
BLAST of Innexin vs. Ensembl Fly
Match: Inx2 (gene:FBgn0027108 transcript:FBtr0071005) HSP 1 Score: 88.9669 bits (219), Expect = 6.183e-19 Identity = 80/292 (27.40%), Postives = 127/292 (43.49%), Query Frame = 3 Query: 330 KSYVIKPISCYLSIGPSGGNFQDYIENYCWIHGTIPLYPN----------QKLSDNHV-GWDELERTQKINYYQWVPFILGLQCIMFYIPKLIWQIFCFNQAGTNLDTIIKLSMKMAEI--PISERRVENENIAKIIENMLVLHRDFRDSKIANIRRSVYSKCSLFMSSKRLGTMIVFSYFVTKLLYLTNGIGQLFMIQSVLGFYNYLPTFGSHLFWYIVSGTELETQH-------YFPRVVFCYLKRIRHVGVQNNYVAQCVLPVNMLNEKIYTFLWCWILLVSFATFISI 1145 + Y+ PI C + P G ++ YCWI+ T + Q +HV G DE++ + YYQWV F+L Q I+FY+P+ +W+ + + G +L M + ++ PI +N+ + +LV D I N+ R F +FV + L N IGQ++ + L T+GS + + TELE FP+V C + G + CVLP+N++NEKIY FLW W +++S + IS+ Sbjct: 45 RQYIGDPIDCIVDEIPLG-----VMDTYCWIYSTFTVPERLTGITGRDVVQPGVGSHVEGEDEVKYHK---YYQWVCFVLFFQAILFYVPRYLWKSW---EGG-------RLKMLVMDLNSPIVNDECKNDR-----KKILV------DYFIGNLNRH---------------NFYAFRFFVCEALNFVNVIGQIYFVDFFLD--GEFSTYGSDVLKF----TELEPDERIDPMARVFPKVTKCTFHKYGPSGSVQTHDGLCVLPLNIVNEKIYVFLWFWFIILSIMSGISL 286
BLAST of Innexin vs. Ensembl Fly
Match: Inx2 (gene:FBgn0027108 transcript:FBtr0332314) HSP 1 Score: 88.9669 bits (219), Expect = 6.183e-19 Identity = 80/292 (27.40%), Postives = 127/292 (43.49%), Query Frame = 3 Query: 330 KSYVIKPISCYLSIGPSGGNFQDYIENYCWIHGTIPLYPN----------QKLSDNHV-GWDELERTQKINYYQWVPFILGLQCIMFYIPKLIWQIFCFNQAGTNLDTIIKLSMKMAEI--PISERRVENENIAKIIENMLVLHRDFRDSKIANIRRSVYSKCSLFMSSKRLGTMIVFSYFVTKLLYLTNGIGQLFMIQSVLGFYNYLPTFGSHLFWYIVSGTELETQH-------YFPRVVFCYLKRIRHVGVQNNYVAQCVLPVNMLNEKIYTFLWCWILLVSFATFISI 1145 + Y+ PI C + P G ++ YCWI+ T + Q +HV G DE++ + YYQWV F+L Q I+FY+P+ +W+ + + G +L M + ++ PI +N+ + +LV D I N+ R F +FV + L N IGQ++ + L T+GS + + TELE FP+V C + G + CVLP+N++NEKIY FLW W +++S + IS+ Sbjct: 45 RQYIGDPIDCIVDEIPLG-----VMDTYCWIYSTFTVPERLTGITGRDVVQPGVGSHVEGEDEVKYHK---YYQWVCFVLFFQAILFYVPRYLWKSW---EGG-------RLKMLVMDLNSPIVNDECKNDR-----KKILV------DYFIGNLNRH---------------NFYAFRFFVCEALNFVNVIGQIYFVDFFLD--GEFSTYGSDVLKF----TELEPDERIDPMARVFPKVTKCTFHKYGPSGSVQTHDGLCVLPLNIVNEKIYVFLWFWFIILSIMSGISL 286
BLAST of Innexin vs. Ensembl Fly
Match: Inx2 (gene:FBgn0027108 transcript:FBtr0071006) HSP 1 Score: 88.9669 bits (219), Expect = 6.183e-19 Identity = 80/292 (27.40%), Postives = 127/292 (43.49%), Query Frame = 3 Query: 330 KSYVIKPISCYLSIGPSGGNFQDYIENYCWIHGTIPLYPN----------QKLSDNHV-GWDELERTQKINYYQWVPFILGLQCIMFYIPKLIWQIFCFNQAGTNLDTIIKLSMKMAEI--PISERRVENENIAKIIENMLVLHRDFRDSKIANIRRSVYSKCSLFMSSKRLGTMIVFSYFVTKLLYLTNGIGQLFMIQSVLGFYNYLPTFGSHLFWYIVSGTELETQH-------YFPRVVFCYLKRIRHVGVQNNYVAQCVLPVNMLNEKIYTFLWCWILLVSFATFISI 1145 + Y+ PI C + P G ++ YCWI+ T + Q +HV G DE++ + YYQWV F+L Q I+FY+P+ +W+ + + G +L M + ++ PI +N+ + +LV D I N+ R F +FV + L N IGQ++ + L T+GS + + TELE FP+V C + G + CVLP+N++NEKIY FLW W +++S + IS+ Sbjct: 45 RQYIGDPIDCIVDEIPLG-----VMDTYCWIYSTFTVPERLTGITGRDVVQPGVGSHVEGEDEVKYHK---YYQWVCFVLFFQAILFYVPRYLWKSW---EGG-------RLKMLVMDLNSPIVNDECKNDR-----KKILV------DYFIGNLNRH---------------NFYAFRFFVCEALNFVNVIGQIYFVDFFLD--GEFSTYGSDVLKF----TELEPDERIDPMARVFPKVTKCTFHKYGPSGSVQTHDGLCVLPLNIVNEKIYVFLWFWFIILSIMSGISL 286
BLAST of Innexin vs. Ensembl Fly
Match: Inx3 (gene:FBgn0265274 transcript:FBtr0085350) HSP 1 Score: 78.1814 bits (191), Expect = 2.746e-15 Identity = 71/277 (25.63%), Postives = 116/277 (41.88%), Query Frame = 3 Query: 348 PISCYLSIGPSGGNFQDYIENYCWIHGT--IPLYPNQKLSDNHVG---WDELERTQKI-NYYQWVPFILGLQCIMFYIPKLIWQIFCFNQAGTNLDTIIKLSMKMAEIPISERRVENENIAKIIENMLVLHRDFRDSKIANIRRSVYSKCSLFMSSKRLGTMIVFSYFVTKLLYLTNGIGQLFMIQSVLGFYNYLPTFGSHLFWYIVSGTELETQ-----HYFPRVVFCYLKRIRHVGVQNNYVAQCVLPVNMLNEKIYTFLWCWILLVSFATFISI 1145 PISC G I +CWI T IP ++++ + G +E + ++ +YYQWVPF+L Q +MFY+P +W+ N + I M +P RR + I K N L H + F+YF +LL N I +FM+ LG ++G+ + + S + + + FPR+ C + G + CVL +N+LNEKIY FLW W ++++ + +++ Sbjct: 57 PISCI----NDGAIPMHVINTFCWITYTYTIPGQQHRQIGTDVAGPGLGNEYGQEKRYHSYYQWVPFVLFFQGLMFYVPHWVWK----NMEDGKIRMITDGLRGMVSVPDDYRRDRQDRILKYFVNSLNTHNGYS-----------------------------FAYFFCELLNFINVIVNIFMVDKFLG--GAFMSYGTDVLKF--SNMDQDKRFDPMIEIFPRLTKCTFHKFGPSGSVQKHDTLCVLALNILNEKIYIFLWFWFIILATISGVAV 292
BLAST of Innexin vs. UniProt/SwissProt
Match: sp|A8WVX4|INX19_CAEBR (Innexin-19 OS=Caenorhabditis briggsae OX=6238 GN=inx-19 PE=3 SV=3) HSP 1 Score: 189.504 bits (480), Expect = 3.181e-53 Identity = 139/430 (32.33%), Postives = 227/430 (52.79%), Query Frame = 3 Query: 228 LNAVHNYGLEDLADKMXXXXXXXXXXXXXXXXXXKSYVIKPISCYLSIGP-SGGNFQDYIENYCWIHGT--IPLYPNQKLSDNHVGWDELERTQKINYYQWVPFILGLQCIMFYIPKLIWQIFCFNQAGTNLDTIIKLSM-KMAEIPISERRVENENIA-KIIENMLVLHRDFRDSKIANIRRSVYSKCSLFMSSKRLGTMIVFSYFVTKLLYLTNGIGQLFMIQSVLGFYNYLPTFGSHLFWYIVSGTELETQHYFPRVVFCYLKRIRHVGVQNNYVAQCVLPVNMLNEKIYTFLWCWILLVSFATFISIPLWINRLYRADVREHYIGNFLQMLNSYDEHKK---------------------PLIHKFINDFLRHDGLFLLRMISNNAGDLIAAYLVNNLWDIYLKKYQNRNLRKDIFSVSNHLKEDE 1439 ++A+ G +D D+++ ++ LIL+VC +++ K Y PI C+ + P S + ++YIE+YCWI T IP+Y N + D+H +E ++I YYQWVPFIL + +MF +P + W++ C Q+G N+ T+I + A + S+R+ E I ++N+ + + R I R +S+ F+S G I Y TKLLY N + Q F++ + L ++ FG + I +G +FPRV C + +R++ N Y QC L +N++NEK++ FLWCW ++++ T S WI + + Y+ F+Q+ S E+KK L+ F++DFL+ DG+ +LRMISN+AGD+I LV NLW ++Y+ RN R+ F +K+ E Sbjct: 12 ISALSVRGDDDAVDRLNYYYTPLILAVCCLVISAKQYGGTPIECW--VNPHSRESMEEYIESYCWIQNTYWIPMYEN--VPDDHTAREE----KQIGYYQWVPFILIAEALMFSLPCIFWRL-CSFQSGLNIQTLINAACDAQALLDYSDRQKAVEAITCNFVDNLDLQSPNGRIRARGWIARIKFSR---FLS----GQCISIVYSFTKLLYSVNVVAQFFILNACLKSSEFV-FFGFQVLSDIWAGRPWTETGHFPRVTLCDFE-VRYLANLNRYTVQCALLINIINEKVFAFLWCWYMILAIITTCSFIYWIANSFIHSEKVDYVMKFIQIAES-SEYKKLQKFEKDATVERLYTVIAFAPHLLDSFVSDFLKSDGILMLRMISNHAGDMIVVQLVRNLW----QEYRERNWRE--FEEHEEMKDVE 416
BLAST of Innexin vs. UniProt/SwissProt
Match: sp|O61715|INX19_CAEEL (Innexin-19 OS=Caenorhabditis elegans OX=6239 GN=inx-19 PE=1 SV=2) HSP 1 Score: 186.037 bits (471), Expect = 9.363e-52 Identity = 138/430 (32.09%), Postives = 227/430 (52.79%), Query Frame = 3 Query: 228 LNAVHNYGLEDLADKMXXXXXXXXXXXXXXXXXXKSYVIKPISCYLSIGP-SGGNFQDYIENYCWIHGT--IPLYPNQKLSDNHVGWDELERTQKINYYQWVPFILGLQCIMFYIPKLIWQIFCFNQAGTNLDTIIKLSMK-MAEIPISERRVENENIAK-IIENMLVLHRDFRDSKIANIRRSVYSKCSLFMSSKRLGTMIVFSYFVTKLLYLTNGIGQLFMIQSVLGFYNYLPTFGSHLFWYIVSGTELETQHYFPRVVFCYLKRIRHVGVQNNYVAQCVLPVNMLNEKIYTFLWCWILLVSFATFISIPLWINRLYRADVREHYIGNFLQMLNSYDEHKK---------------------PLIHKFINDFLRHDGLFLLRMISNNAGDLIAAYLVNNLWDIYLKKYQNRNLRKDIFSVSNHLKEDE 1439 +NA+ G +D D+++ ++ LIL+VC +++ K Y PI C+ + P S + ++YIE+YCWI T IP+Y N + D+H +E ++I YYQWVPFIL + +MF +P + W++ C Q+G N+ T+I + A + S+R+ E I ++N+ + + R I R +S+ F+S + L + F TKLLY N + Q ++ + L ++L FG + I +G +FPRV C + +R++ N Y QC L +N++NEK++ FLWCW ++++ T S WI + + Y+ F+Q+ S E KK L+ F++DFL+ DG+ +LRMISN+AGD+I LV NLW ++++ RN R+ F +K+ E Sbjct: 28 INALSVRGDDDAVDRLNYYYTPLILAVCCLVISAKQYGGTPIECW--VNPHSRESMEEYIESYCWIQNTYWIPMYEN--VPDDHTAREE----KQIGYYQWVPFILIAEALMFSLPCIFWRL-CSFQSGLNIQTLINAACDGQALLDASDRQKAVEAITTNFVDNLDLQSPNGRIRARGWIARIKFSR---FLSGQCLSILHSF----TKLLYSMNVVAQFLILNACLKSSDFL-FFGFQVLNDIWAGRPWTETGHFPRVTLCDFE-VRYLANLNRYTVQCALLINIINEKVFAFLWCWYMILAIITTCSFIYWIANSFIHSEKVDYVMKFIQIAES-SEFKKLQKFEKDATVERLYTVIAFAPHLLDTFVSDFLKSDGVLMLRMISNHAGDMIVVQLVRNLW----QEFRERNWRE--FEEHEEMKDVE 432
BLAST of Innexin vs. UniProt/SwissProt
Match: sp|O01393|UNC9_CAEEL (Innexin unc-9 OS=Caenorhabditis elegans OX=6239 GN=unc-9 PE=1 SV=1) HSP 1 Score: 180.644 bits (457), Expect = 2.267e-50 Identity = 112/379 (29.55%), Postives = 202/379 (53.30%), Query Frame = 3 Query: 255 EDLADKMXXXXXXXXXXXXXXXXXXKSYVIKPISCYLSIGPSGGNFQDYIENYCWIHGTIPLYPNQKLSDNHVGWDELERTQKINYYQWVPFILGLQCIMFYIPKLIWQIFCFNQAGTNLDTIIKLSMKMAEIPISERRVENENIAKIIENML-VLHRDFRDSKIANIRRSVYSKCSLFMSSKRLGTMIVFSYFVTKLLYLTNGIGQLFMIQSVLGFYNYLPTFGSHLFWYIVSGTELETQHYFPRVVFCYLKRIRHVGVQNNYVAQCVLPVNMLNEKIYTFLWCWILLVSFATFISIPLWINRLYRADVREHYIGNFLQMLNSYDEHKKPLIHKFINDFLRHDGLFLLRMISNNAGDLIAAYLVNNLWDIYLKKYQNR 1388 +D+ DK++ ++ I++V +V+ K YV PI C++ + Y ENYCW+ T L + + N+ E E Q I YYQWVPF+L L+ ++FY+P ++W++ + Q+G ++ ++++++ + + R + IA +E L V H+ +++ + +L + ++ G + F Y K+LY N +GQ+F++ + LG N +G + +++G E E +FPRV C + ++ +G + + QCVL +NM NEKI+ FLW W L++ AT S+ WI + +++G +L + Y + +F+ FLR DG+FLLRM++ +AG+L L LW+ Y + + Sbjct: 21 DDIIDKLNYYYTTAIITVFAILVSAKQYVGFPIQCWVP-ATFTEPMEQYTENYCWVQNTYFLPLHDYIPHNYA---ERENRQ-IGYYQWVPFVLALEALLFYVPTIVWRLLSW-QSGIHVQSLVQMACDSRLLDLESRNRALQTIATNVEEALHVKHQVMSGNRLKLL--------NLIICTRSSGAAVTFLYISVKILYTVNIVGQIFLLNTFLG--NRSKWYGLQVLNDLMNGREWEESGHFPRVTLCDFE-VKVLGNVHRHTVQCVLMINMFNEKIFLFLWFWYFLLAGATLCSLFYWIYISVVPSRQLNFVGKYLTGIEGYKMVDSQSLRRFVFHFLRQDGVFLLRMVATHAGELPCYELAKTLWNNYCDNKEGK 382
BLAST of Innexin vs. UniProt/SwissProt
Match: sp|Q03412|UNC7_CAEEL (Innexin unc-7 OS=Caenorhabditis elegans OX=6239 GN=unc-7 PE=1 SV=1) HSP 1 Score: 166.392 bits (420), Expect = 5.403e-44 Identity = 120/404 (29.70%), Postives = 204/404 (50.50%), Query Frame = 3 Query: 195 VANEFFSLINRLNAVHNYGLEDLADKMXXXXXXXXXXXXXXXXXXKSYVIKPISCYLSIGPSGGNFQDYIENYCWIHGT--IPLY---PNQKLSDNHVGWDELERTQKINYYQWVPFILGLQCIMFYIPKLIWQIFCFNQAGTNLDTIIKLSMKMAEIPISERRVENENIAKIIENMLVLHRDFRDSKIANI-----RRSVYSKCSLFMSSKR-LGTMIVFSYFVTKLLYLTNGIGQLFMIQSVLGFYNYLPTFGSHLFWYIVSGTELETQHYFPRVVFCYLKRIRHVGVQNNYVAQCVLPVNMLNEKIYTFLWCWILLVSFATFISIPLWINRLYRADVREHYIGNFLQMLNSYDEHKKPL-----IHKFINDFLRHDGLFLLRMISNNAGDLIAAYLVNNLW 1358 +A+ F +L RL+ +D DK++ ++ IL+ +V+ K YV PI C++ + + Y ENYCW+ T +P+ P + S R ++I YYQWVPFIL ++ ++FY+P ++W+ + +G NL +++++ R +++E + + M +D + ++ NI RS +S L + R G + Y K+LY N + Q F++ +LG + +G L ++ E E FPRV C + +R +G + + QCVL +NM NEKI+ FLW W L T + WI ++ ++ +L++L D KP+ + KF N+FLR DG+F+LRMIS +AG+L+++ L+ LW Sbjct: 126 LASAFRALYPRLD-------DDFVDKLNYYYTTTILASFALLVSAKQYVGFPIQCWVPATFTDA-MEQYTENYCWVQNTYWVPMQEDIPREIYS---------RRNRQIGYYQWVPFILAIEALLFYVPCILWRGLLYWHSGINLQGLVQMA-------CDARLMDSEIKTRTVYTMARHMQD--EVQLTNIDRQGHSRSCFSNLQLGANCGRHCGCYVTMLYIGIKVLYSANVLLQFFLLNHLLGSNDL--AYGFSLLKDLMHAIEWEQTGMFPRVTLCDFE-VRVLGNIHRHTVQCVLMINMFNEKIFLFLWFWFLTCGIVTVCNTMYWILIMFIPSQGMSFVRKYLRVLP--DHPAKPIADDVTLRKFTNNFLRKDGVFMLRMISTHAGELMSSELILALW 498
BLAST of Innexin vs. UniProt/SwissProt
Match: sp|Q19746|INX3_CAEEL (Innexin-3 OS=Caenorhabditis elegans OX=6239 GN=inx-3 PE=1 SV=2) HSP 1 Score: 161.384 bits (407), Expect = 5.373e-43 Identity = 112/382 (29.32%), Postives = 186/382 (48.69%), Query Frame = 3 Query: 252 LEDLADKMXXXXXXXXXXXXXXXXXXKSYVIKPISCYLSIGPSGGNFQDYIENYCWIHGTIPLYPNQKLSDNHVGWDELERTQKINYYQWVPFILGLQCIMFYIPKLIWQIFCFNQAGTNLDTIIKLSMKMAEIPISERRVENENIAKIIENMLVLHRDFRDSKIANIRRSVYSKCSLFMSSKRLGTMIVFSYFVTKLLYLTNGIGQLFMIQSVLGFYNYLPTFGSHLFWYIVSGTELETQHYFPRVVFCYLKRIRHVGVQNNYVAQCVLPVNMLNEKIYTFLWCWILLVSFATFISIPLWINRLYRADVREHYIGNFLQMLNSYDEHKKPLIHKFINDFLRHDGLFLLRMISNNAGDLIAAYLVNNLWDIYLKKYQ-NRNL 1394 +D D++S + + +L+ +V+ K YV I C++ + GG ++ Y E+YC+I T + ++ G E + +I YYQWVP +L +Q MFY+P IW + Q G + ++I + + R ++E K + ++ D D++ N Y + + K LG+M Y KL+YL N Q ++ LG +L +G H F + +G E + FPRV C +R + + Y QCVL +NM NEKIY F+W W + V TFI+ I RL R +YI + L + + +K +I F N+ L+ DG+ L+R I ++AG ++ + L+ + + Q NR+ Sbjct: 20 FDDAVDRLSYVTTATLLAFFSIMVSCKQYVGSAIQCWMPMEFKGG-WEQYAEDYCFIQNTFFIPERSEIP----GDVEDRQKAEIGYYQWVPIVLAIQAFMFYLPSWIWSSL-YKQCGLDFPSVISEAEAL-------RSQDSETRTKGVNKLVDFIGDILDTRSKN----EYGRFYCYRFGKGLGSMTSMLYICIKLMYLANVFVQFIILNKFLGNETFL--WGFHTFADLYAGREWQDSGVFPRVTLCDFS-VRKLANVHRYTVQCVLMINMFNEKIYLFIWFWFVFVLITTFINTLCTIYRLSFDSSRHNYIRSLLSGPVNNFKDEKAMIASFANNGLKQDGVLLMRFIDDHAGAMVTKEICEELFKKHGENLQHNRDF 381
BLAST of Innexin vs. TrEMBL
Match: A0A564YPR7 (Innexin OS=Hymenolepis diminuta OX=6216 GN=inx PE=3 SV=1) HSP 1 Score: 404.445 bits (1038), Expect = 8.988e-134 Identity = 189/405 (46.67%), Postives = 279/405 (68.89%), Query Frame = 3 Query: 192 MVANEFFSLINRLNAVHNYGLEDLADKMXXXXXXXXXXXXXXXXXXKSYVIKPISCYLSIGPSGGNFQDYIENYCWIHGTIPLYPNQKLSDNHVGWDELERTQKINYYQWVPFILGLQCIMFYIPKLIWQIFCFNQAGTNLDTIIKLSMKMAEIPISERRVENENIAKIIENMLVLHRDFRDSKIANIRRSVYSKCSLFMSSKRLGTMIVFSYFVTKLLYLTNGIGQLFMIQSVLGFYNYLPTFGSHLFWYIVSGTELETQHYFPRVVFCYLKRIRHVGVQNNYVAQCVLPVNMLNEKIYTFLWCWILLVSFATFISIPLWINRLYRADVREHYIGNFLQMLNSYDEHKKPLIHKFINDFLRHDGLFLLRMISNNAGDLIAAYLVNNLWDIYLKKYQNRNLRKDI 1406 MV EF + +L GLED ADKMS ++SVLIL +C +I+ +K Y++ I+CY+ PSG +F +++N+CW+HGTIPL + + N WDE ++ +INYYQWVPF+LGLQCI+FYIP++IWQI C+N+ GT+L+ +I ++ K + +R+ +++A + ML HRD+R ++A+ RR + C +F++SKRLGT ++F+Y K +YL N IGQL+++Q+ LGF + FG + Y+++G + + FPRV FCY++ +RH+G N YVAQCVLPVNMLNEK+Y FLW W +V+F T +SIPLWI RL R +EH+I FL++ Y+ + ++H F +DFLRHDG+FLLRMIS NAGD++ A ++ +WDIY K++NR + DI Sbjct: 1 MVGVEFIDYLTKLRVNDFLGLEDFADKMSFMYSVLILLLCTTIIAVKQYLLASIACYIPTVPSGKDFDKFLQNFCWVHGTIPLLEGEHIPQNFSEWDEADKNLRINYYQWVPFMLGLQCILFYIPRVIWQIICYNRTGTDLENLISIANKASNTIEGDRQSLVKHVAGTMAEMLFQHRDYRVGRVADARRKAFKFCGVFVASKRLGTWLIFTYLFIKCIYLANAIGQLYLMQTFLGFNKSMTNFGYEVAKYMINGKDWDETRIFPRVSFCYVEHVRHLGTTNRYVAQCVLPVNMLNEKLYIFLWFWTAIVAFCTAVSIPLWIMRLGRQKNKEHFIKKFLRLQEIYNTKDREILHNFTSDFLRHDGVFLLRMISMNAGDVVTADVIVKMWDIYKTKFKNRIMLNDI 405
BLAST of Innexin vs. TrEMBL
Match: Q2L6M6 (Innexin OS=Dugesia japonica OX=6161 GN=inx9 PE=2 SV=1) HSP 1 Score: 397.127 bits (1019), Expect = 9.147e-131 Identity = 188/401 (46.88%), Postives = 270/401 (67.33%), Query Frame = 3 Query: 192 MVANEFFSLINRLNAVHNYGLEDLADKMXXXXXXXXXXXXXXXXXXKSYVIKPISCYLSIGPSGGNFQDYIENYCWIHGTIPLYPNQKLSDNHVGWDELERTQKINYYQWVPFILGLQCIMFYIPKLIWQIFCFNQAGTNLDTIIKLSMKMAEIPISERRVENENIAKIIENMLVLHRDFRDSKIANIRRSVYSKCSLFMSSKRLGTMIVFSYFVTKLLYLTNGIGQLFMIQSVLGFYNYLPTFGSHLFWYIVSGTELETQHYFPRVVFCYLKRIRHVGVQNNYVAQCVLPVNMLNEKIYTFLWCWILLVSFATFISIPLWINRLYRADVREHYIGNFLQMLNSYDEHKKPLIHKFINDFLRHDGLFLLRMISNNAGDLIAAYLVNNLWDIYLKKYQNRNL 1394 MVA EF SL+ + G+ED ADK++ +FSV+IL + + +VT+KSY KP++CY++ PSG NF +Y+ENYCW+HGTI + P + + W +++T++I YYQWVPFILGLQCIMFY+P++IWQ+ C+N+ GTNL+++ + + P SER+ + E I + IE+ML HRD+R K+A++RR++Y C+ + SK +GT +V SY + K +Y N IGQLF+++ LGF + + +FG + I G E FPRV +CY+ I+H+G N YV QC LP+NMLNEKIY FLW W+ LV T ISIP+W R+ R +I FL M +Y+ K LI+ FI +FLRHDG+FL+RMI NAGD++ A +VN LW+IY + Y+N + Sbjct: 1 MVAQEFLSLVGQFKLTSYVGVEDFADKLNFLFSVVILIISMMVVTVKSYFFKPLACYIATTPSGSNFDNYLENYCWVHGTISILPGENIPQTDADWAIVDQTKRITYYQWVPFILGLQCIMFYVPRVIWQLICYNKVGTNLESLAIDADAASHSPPSERKDKIERIVRTIEDMLFQHRDYRQGKMADMRRNIYKMCNFCVFSKHMGTWLVLSYILMKFMYGINVIGQLFLMKKFLGFNSSMSSFGYTILSNIADGKEWHQTGIFPRVTYCYIGEIKHLGASNKYVGQCALPINMLNEKIYVFLWFWVFLVGIITAISIPMWFFRIAILSRRSSFIKKFLMMHQAYNRSDKQLINSFIREFLRHDGVFLIRMICINAGDIVTADIVNRLWEIYKENYKNMDF 401
BLAST of Innexin vs. TrEMBL
Match: Q2L6M7 (Innexin OS=Dugesia japonica OX=6161 GN=inx8 PE=2 SV=1) HSP 1 Score: 395.971 bits (1016), Expect = 2.059e-130 Identity = 192/402 (47.76%), Postives = 273/402 (67.91%), Query Frame = 3 Query: 192 MVANEFFSLINRLNAVHNYGLEDLADKMXXXXXXXXXXXXXXXXXXKSYVIKPISCYLSIGPSGGNFQDYIENYCWIHGTIPLYPNQKLSDNHVGWDELERTQKINYYQWVPFILGLQCIMFYIPKLIWQIFCFNQAGTNLDTIIKLSMKMAEIPISERRVENENIAKIIENMLVLHRDFRDSKIANIRRSVYSKCSLFMSSKRLGTMIVFSYFVTKLLYLTNGIGQLFMIQSVLGFYNYLPTFGSHLFWYIVSGTELETQHYFPRVVFCYLKRIRHVGVQNNYVAQCVLPVNMLNEKIYTFLWCWILLVSFATFISIPLWINRLYRADVREHYIGNFLQMLNSYDEHKKPLIHKFINDFLRHDGLFLLRMISNNAGDLIAAYLVNNLWDIYLKKYQNRNLR 1397 MVA EFFSL++ G+ED ADKM+ +FSV+++ + + +VT+KSY KP+SCY++ PSG F +YIENYCW+HGTIP+ P + + W E + ++I YYQWVPFILGLQCIMFY PK+IWQI C+N+ GTNL+ ++ + + ++ P +R+ + I++ IE+ML HRD+R KIAN RR++YS+C+ + SK LGT +V SYF K+LY N IGQL++++S LGF N L FG + +++G E FPRV +CY IRH+G N YV+QC LP+NMLNEKIY FLW W+LLV T ISI W+ ++ R +I L+M SY + L+++FI ++LRHDG+FL+RMI NAGD++ A ++ LW+IY +KY + + R Sbjct: 1 MVAEEFFSLLSEFKVSSYVGVEDFADKMNFMFSVVLIILSMMVVTVKSYFFKPLSCYIATTPSGSGFDNYIENYCWVHGTIPILPGENIPQKTNEWAEWDANKRITYYQWVPFILGLQCIMFYTPKIIWQIICYNKIGTNLENLVNGAEEASKSPPEDRKALLDRISRTIEDMLYQHRDYRQGKIANTRRALYSRCNFLVFSKHLGTWLVLSYFFIKVLYGINVIGQLYLMKSFLGFDNSLTYFGYTILENMLNGKEWHQTGIFPRVSYCYNADIRHLGSTNAYVSQCTLPINMLNEKIYVFLWFWVLLVGIITLISIISWLIKMVFLSKRSSFIKKLLKMHQSYKRTDQLLVNQFIKEYLRHDGVFLIRMICINAGDIVTAEILGTLWEIYKEKYIDSDFR 402
BLAST of Innexin vs. TrEMBL
Match: W6UMB0 (Innexin OS=Echinococcus granulosus OX=6210 GN=inx PE=3 SV=1) HSP 1 Score: 398.282 bits (1022), Expect = 2.102e-130 Identity = 187/405 (46.17%), Postives = 279/405 (68.89%), Query Frame = 3 Query: 192 MVANEFFSLINRLNAVHNYGLEDLADKMXXXXXXXXXXXXXXXXXXKSYVIKPISCYLSIGPSGGNFQDYIENYCWIHGTIPLYPNQKLSDNHVGWDELERTQKINYYQWVPFILGLQCIMFYIPKLIWQIFCFNQAGTNLDTIIKLSMKMAEIPISERRVENENIAKIIENMLVLHRDFRDSKIANIRRSVYSKCSLFMSSKRLGTMIVFSYFVTKLLYLTNGIGQLFMIQSVLGFYNYLPTFGSHLFWYIVSGTELETQHYFPRVVFCYLKRIRHVGVQNNYVAQCVLPVNMLNEKIYTFLWCWILLVSFATFISIPLWINRLYRADVREHYIGNFLQMLNSYDEHKKPLIHKFINDFLRHDGLFLLRMISNNAGDLIAAYLVNNLWDIYLKKYQNRNLRKDI 1406 MV EF + +L+ GLED ADKMS ++SVLIL +C +I+ +K Y++ I+CY+ PSG +F+ +++N+CW+HGTIP+ + + N+ W + + +INYYQWVPF+LGLQCI+FY+P+++WQI C+N+ GT+L+ +I ++ K + ++R++ +++A + ML HRD+R K+A+ RR + +F++SKRLGT ++F+Y K +YL N IGQL+++Q+ LGF + FG + Y+V+G + + FPRV FCYL+ +RH+G N YVAQCVLPVNMLNEK+Y FLW W +V+ T +SIPLWI RL R + H+I FL++ + Y K ++ FI+DFLRHDG+FLLRMIS NAGD++ A +V +WDIY KY+NR + DI Sbjct: 61 MVGIEFIDYLTKLHVSDFLGLEDFADKMSFMYSVLILLLCTTIIAVKQYLLASIACYIPTVPSGKDFEKFLQNFCWVHGTIPILEGEHIPQNYSEWHDADENMRINYYQWVPFMLGLQCILFYVPRVVWQIICYNRTGTDLENLIAVANKASNTIENDRKMLVKHVAGTMAEMLFQHRDYRRGKVADARRKAFKFFGMFIASKRLGTWLIFTYLFIKCIYLANAIGQLYLMQTFLGFNKSMSNFGYEVARYMVNGRDWDETRIFPRVSFCYLEHVRHLGTTNRYVAQCVLPVNMLNEKLYIFLWFWTAIVAVCTAVSIPLWIMRLGREKNKVHFIKKFLRLQDIYTPEHKEILRNFISDFLRHDGVFLLRMISMNAGDVVTADVVVEMWDIYKTKYKNRAMLNDI 465
BLAST of Innexin vs. TrEMBL
Match: A0A068WGF5 (Innexin OS=Echinococcus granulosus OX=6210 GN=inx PE=3 SV=1) HSP 1 Score: 397.512 bits (1020), Expect = 2.114e-130 Identity = 187/405 (46.17%), Postives = 279/405 (68.89%), Query Frame = 3 Query: 192 MVANEFFSLINRLNAVHNYGLEDLADKMXXXXXXXXXXXXXXXXXXKSYVIKPISCYLSIGPSGGNFQDYIENYCWIHGTIPLYPNQKLSDNHVGWDELERTQKINYYQWVPFILGLQCIMFYIPKLIWQIFCFNQAGTNLDTIIKLSMKMAEIPISERRVENENIAKIIENMLVLHRDFRDSKIANIRRSVYSKCSLFMSSKRLGTMIVFSYFVTKLLYLTNGIGQLFMIQSVLGFYNYLPTFGSHLFWYIVSGTELETQHYFPRVVFCYLKRIRHVGVQNNYVAQCVLPVNMLNEKIYTFLWCWILLVSFATFISIPLWINRLYRADVREHYIGNFLQMLNSYDEHKKPLIHKFINDFLRHDGLFLLRMISNNAGDLIAAYLVNNLWDIYLKKYQNRNLRKDI 1406 MV EF + +L+ GLED ADKMS ++SVLIL +C +I+ +K Y++ I+CY+ PSG +F+ +++N+CW+HGTIP+ + + N+ W + + +INYYQWVPF+LGLQCI+FY+P+++WQI C+N+ GT+L+ +I ++ K + ++R++ +++A + ML HRD+R K+A+ RR + +F++SKRLGT ++F+Y K +YL N IGQL+++Q+ LGF + FG + Y+V+G + + FPRV FCYL+ +RH+G N YVAQCVLPVNMLNEK+Y FLW W +V+ T +SIPLWI RL R + H+I FL++ + Y K ++ FI+DFLRHDG+FLLRMIS NAGD++ A +V +WDIY KY+NR + DI Sbjct: 1 MVGIEFIDYLTKLHVSDFLGLEDFADKMSFMYSVLILLLCTTIIAVKQYLLASIACYIPTVPSGKDFEKFLQNFCWVHGTIPILEGEHIPQNYSEWHDADENMRINYYQWVPFMLGLQCILFYVPRVVWQIICYNRTGTDLENLIAVANKASNTIENDRKMLVKHVAGTMAEMLFQHRDYRRGKVADARRKAFKFFGMFIASKRLGTWLIFTYLFIKCIYLANAIGQLYLMQTFLGFNKSMSNFGYEVARYMVNGRDWDETRIFPRVSFCYLEHVRHLGTTNRYVAQCVLPVNMLNEKLYIFLWFWTAIVAVCTAVSIPLWIMRLGREKNKVHFIKKFLRLQDIYTPEHKEILRNFISDFLRHDGVFLLRMISMNAGDVVTADVVVEMWDIYKTKYKNRAMLNDI 405
BLAST of Innexin vs. Planmine SMEST
Match: SMESG000053975.1 (SMESG000053975.1) HSP 1 Score: 828.935 bits (2140), Expect = 0.000e+0 Identity = 437/437 (100.00%), Postives = 437/437 (100.00%), Query Frame = 3 Query: 192 MVANEFFSLINRLNAVHNYGLEDLADKMXXXXXXXXXXXXXXXXXXKSYVIKPISCYLSIGPSGGNFQDYIENYCWIHGTIPLYPNQKLSDNHVGWDELERTQKINYYQWVPFILGLQCIMFYIPKLIWQIFCFNQAGTNLDTIIKLSMKMAEIPISERRVENENIAKIIENMLVLHRDFRDSKIANIRRSVYSKCSLFMSSKRLGTMIVFSYFVTKLLYLTNGIGQLFMIQSVLGFYNYLPTFGSHLFWYIVSGTELETQHYFPRVVFCYLKRIRHVGVQNNYVAQCVLPVNMLNEKIYTFLWCWILLVSFATFISIPLWINRLYRADVREHYIGNFLQMLNSYDEHKKPLIHKFINDFLRHDGLFLLRMISNNAGDLIAAYLVNNLWDIYLKKYQNRNLRKDIFSVSNHLKEDEAXXXXXXXXXXXXXXPIMNYL 1502 MVANEFFSLINRLNAVHNYGLEDLADKMSSIFSVLILSVCVSIVTIKSYVIKPISCYLSIGPSGGNFQDYIENYCWIHGTIPLYPNQKLSDNHVGWDELERTQKINYYQWVPFILGLQCIMFYIPKLIWQIFCFNQAGTNLDTIIKLSMKMAEIPISERRVENENIAKIIENMLVLHRDFRDSKIANIRRSVYSKCSLFMSSKRLGTMIVFSYFVTKLLYLTNGIGQLFMIQSVLGFYNYLPTFGSHLFWYIVSGTELETQHYFPRVVFCYLKRIRHVGVQNNYVAQCVLPVNMLNEKIYTFLWCWILLVSFATFISIPLWINRLYRADVREHYIGNFLQMLNSYDEHKKPLIHKFINDFLRHDGLFLLRMISNNAGDLIAAYLVNNLWDIYLKKYQNRNLRKDIFSVSNHLKEDEANNSTSNSQNLNQCSPIMNYL Sbjct: 1 MVANEFFSLINRLNAVHNYGLEDLADKMSSIFSVLILSVCVSIVTIKSYVIKPISCYLSIGPSGGNFQDYIENYCWIHGTIPLYPNQKLSDNHVGWDELERTQKINYYQWVPFILGLQCIMFYIPKLIWQIFCFNQAGTNLDTIIKLSMKMAEIPISERRVENENIAKIIENMLVLHRDFRDSKIANIRRSVYSKCSLFMSSKRLGTMIVFSYFVTKLLYLTNGIGQLFMIQSVLGFYNYLPTFGSHLFWYIVSGTELETQHYFPRVVFCYLKRIRHVGVQNNYVAQCVLPVNMLNEKIYTFLWCWILLVSFATFISIPLWINRLYRADVREHYIGNFLQMLNSYDEHKKPLIHKFINDFLRHDGLFLLRMISNNAGDLIAAYLVNNLWDIYLKKYQNRNLRKDIFSVSNHLKEDEANNSTSNSQNLNQCSPIMNYL 437
BLAST of Innexin vs. Planmine SMEST
Match: SMESG000080788.1 (SMESG000080788.1) HSP 1 Score: 404.831 bits (1039), Expect = 1.972e-137 Identity = 198/402 (49.25%), Postives = 272/402 (67.66%), Query Frame = 3 Query: 192 MVANEFFSLINRLNAVHNYGLEDLADKMXXXXXXXXXXXXXXXXXXKSYVIKPISCYLSIGPSGGNFQDYIENYCWIHGTIPLYPNQKLSDNHVGWDELERTQKINYYQWVPFILGLQCIMFYIPKLIWQIFCFNQAGTNLDTIIKLSMKMAEIPISERRVENENIAKIIENMLVLHRDFRDSKIANIRRSVYSKCSLFMSSKRLGTMIVFSYFVTKLLYLTNGIGQLFMIQSVLGFYNYLPTFGSHLFWYIVSGTELETQHYFPRVVFCYLKRIRHVGVQNNYVAQCVLPVNMLNEKIYTFLWCWILLVSFATFISIPLWINRLYRADVREHYIGNFLQMLNSYDEHKKPLIHKFINDFLRHDGLFLLRMISNNAGDLIAAYLVNNLWDIYLKKYQNRNLR 1397 MVA EF +LI + G+ED ADK+S +FSV +L + + +VTIKSY+ KP++CY + P G NF++Y+ENYCW+HGTI P + + N V W + T++INYYQWVPFILGLQC MFYIPK+IWQI C+N++GTNL++I+ + P ER+ + E IA+ IE+ML HRD+R A +RR +Y+ C+ + SK +GT ++ SY + K LY N IGQLF+++ LGF N +FG + ++SG E FPRV +CY++ I+HVGV N YVAQC LPVNMLNEKIY FLW W++LV T ISIPLW R+ R +I FL M +Y+ KP+I+ FI +FLRHDG+FL+RM+ NAGD+I A +VN L +IY + Y++ + R Sbjct: 1 MVAEEFLNLIGQFKISTYVGIEDFADKLSFLFSVTLLILSMMVVTIKSYLFKPLACYTATAPGGSNFENYLENYCWVHGTITFLPGEDIPQNDVDWARADDTRRINYYQWVPFILGLQCFMFYIPKIIWQIICYNKSGTNLESIVNDANAANNTPPVERKDKIERIARTIEDMLFQHRDYRQGNFAKLRRKIYNTCNFCVFSKHMGTWLILSYILIKFLYGLNVIGQLFIMKKFLGFNNSTSSFGYTVLSNMISGKEWHQTGIFPRVTYCYVRNIKHVGVANKYVAQCALPVNMLNEKIYVFLWFWMVLVGIVTAISIPLWFYRMAFLSRRSKFIKRFLMMHQNYERSDKPMINNFIEEFLRHDGVFLVRMLFINAGDIITADIVNRLLEIYKENYKHLDFR 402
BLAST of Innexin vs. Planmine SMEST
Match: SMESG000065083.1 (SMESG000065083.1) HSP 1 Score: 347.821 bits (891), Expect = 4.164e-115 Identity = 191/407 (46.93%), Postives = 260/407 (63.88%), Query Frame = 3 Query: 192 MVANEFFSLINRLNAVHNYGLEDLADKMXXXXXXXXXXXXXXXXXXKSYVIKPISCYLSIGPSGGNFQDYIENYCWIHGTIPLYPNQKLSDNHVGWDELERTQKINYYQWVPFILGLQCIMFYIPKLIWQIFCFNQAGTNLDTIIKLSMKMAEIPISERRVENENIAKIIENMLVLHRDFRDSKIANIRRSVYSKCSLFMSSKRLGTMIVFSYFVTKLLYLTNGIGQLFMIQSVLGFYNY-LPTFGSHLFWYIVSGTELETQHYFPRVVFCYLKRIRHVGVQNNYVAQCVLPVNMLNEKIYTFLWCWILLVSFATFISIPLWINRLYRADVREHYIGNFLQMLN--SYDEHKKPLIHKFINDFLRHDGLFLLRMISNNAGDLIAAYLVNNLWDIYLKKYQNRNLRKD 1403 MVA+EF +++L N GLEDL D+++ FSV++L VC+ IVT+K YV KPISCYL G N Y+EN CW+ GTI L K W LE+ K+ YYQWVPF+LGLQCIMFY+PKL+WQI C+N+ GT++ ++ + + R ++K +E +L HRD R K+A RR +++ M SKR+GT +V SY + KL Y+ NG QL ++Q LGF ++ L TFG + I SGT+ +T FPRV +C++K + H+GV N+ VAQCVLPVNMLNE+IY FLWCWIL+V T +SIP+WI R+ R H+I FL + + D+ + L+ KF + FLRHDG+FLL+MIS NAGD+I + +V LW+IY Y NRN D Sbjct: 1 MVASEFLDYLSKLQVSTNVGLEDLPDRLNFTFSVIVLMVCILIVTVKQYVFKPISCYLPNNIGGSNLLSYVENLCWVQGTIALSNQAKFPSTDEEWKNLEK-HKMLYYQWVPFMLGLQCIMFYVPKLVWQIICYNRTGTDIQHLVVSANQAVHSSDEARSKMVSYLSKTLEQLLYQHRDHRSGKLAKFRRKIHNSVGFLMCSKRIGTWLVSSYLLLKLSYVANGFIQLIIMQKFLGFSDFNLLTFGIEVGNNIWSGTDWKTTLIFPRVSYCFVK-VTHLGVINSMVAQCVLPVNMLNERIYFFLWCWILIVLSLTILSIPIWILRILCIKYRRHFIRQFLIISEEITKDQKENYLLAKFESQFLRHDGIFLLKMISLNAGDIITSEIVCQLWNIYKTNYVNRNFLND 405
BLAST of Innexin vs. Planmine SMEST
Match: SMESG000066858.1 (SMESG000066858.1) HSP 1 Score: 332.028 bits (850), Expect = 5.308e-109 Identity = 176/407 (43.24%), Postives = 251/407 (61.67%), Query Frame = 3 Query: 192 MVANEFFSLINRLNAVHNYGLEDLADKMXXXXXXXXXXXXXXXXXXKSYVIKPISCYLSIGPSGGNFQDYIENYCWIHGTIPLYPNQKLSDNHVGWD-ELERT-QKINYYQWVPFILGLQCIMFYIPKLIWQIFCFNQAGTNLDTIIKLSMKMAEIPISERRVENENIAKIIENMLVLHRDFRDSKIANIRRSVYSKCSLFMSSKRLGTMIVFSYFVTKLLYLTNGIGQLFMIQSVLGFY-NYLPTFGSHLFWYIVSGTELETQHYFPRVVFCYLKRIRHVGVQNNYVAQCVLPVNMLNEKIYTFLWCWILLVSFATFISIPLWINRLYRADVREHYIGNFLQMLNSYDEHKKPLIHKFINDFLRHDGLFLLRMISNNAGDLIAAYLVNNLWDIYLKKYQNRNLRKD 1403 MVAN LI GLED+ DK+S SV+I +C IVT K+Y++KP+SCY +I P+G NF Y+ NYCWI GT+P P K VG D +L+ + +KINYYQWVPF+L LQCIMFY+P+L WQ+ +N+ G +L+ I K + + + R+ + + IAK + N+ HRD++ AN RR ++ S FM SKRLGT + + YFV KL++L N +GQL++IQ LGF+ N + F +V+G + T FPRV C + I+ +GV+NNY+ QCVL NMLNEKIY FLW W+ +V T I+I LW ++ R +I FL+ Y + K+ + FI FLRHDG F++ M++ N GDLI +++V+ LW+IY +Y N + + Sbjct: 1 MVANTLLDLIKSHKVTDYQGLEDIGDKISFQISVIIYIICGFIVTSKTYILKPLSCYTAISPTGSNFDGYLRNYCWITGTVPWVPGDKFP--QVGDDMKLDDSLKKINYYQWVPFVLALQCIMFYLPRLFWQLMSYNKIGIDLELIFKDASSASNDDEAARKKKAKGIAKNLANVFFFHRDYKYGTWANFRRKIFKFASFFMMSKRLGTWLTYWYFVMKLMFLANAVGQLYLIQRFLGFHGNNIFETSRVFFDSLVNGVQWTTSRLFPRVTVCSIDNIKLLGVENNYITQCVLSQNMLNEKIYMFLWFWLHIVIVVTLITIGLWCKKIIFLGSRAEFIKKFLKNHEVYRKSKRDSLDNFIQTFLRHDGSFIIMMMTMNCGDLITSHVVSELWEIYQSEYANSDTSSE 405
BLAST of Innexin vs. Planmine SMEST
Match: SMESG000066886.1 (SMESG000066886.1) HSP 1 Score: 332.028 bits (850), Expect = 5.365e-109 Identity = 176/407 (43.24%), Postives = 252/407 (61.92%), Query Frame = 3 Query: 192 MVANEFFSLINRLNAVHNYGLEDLADKMXXXXXXXXXXXXXXXXXXKSYVIKPISCYLSIGPSGGNFQDYIENYCWIHGTIPLYPNQKLSDNHVGWD-ELERT-QKINYYQWVPFILGLQCIMFYIPKLIWQIFCFNQAGTNLDTIIKLSMKMAEIPISERRVENENIAKIIENMLVLHRDFRDSKIANIRRSVYSKCSLFMSSKRLGTMIVFSYFVTKLLYLTNGIGQLFMIQSVLGFYNYLPTFGSHLFW-YIVSGTELETQHYFPRVVFCYLKRIRHVGVQNNYVAQCVLPVNMLNEKIYTFLWCWILLVSFATFISIPLWINRLYRADVREHYIGNFLQMLNSYDEHKKPLIHKFINDFLRHDGLFLLRMISNNAGDLIAAYLVNNLWDIYLKKYQNRNLRKD 1403 MVAN LI GLED+ DK+S SV+I +C IVT K+Y++KP+SCY +I P+G NF Y+ NYCWI GT+P P K VG D +L+ + +KINYYQWVPF+L LQCIMFY+P+L WQ+ +N+ G +L+ I K + + + R+ + + IAK + N+ HRD++ AN RR ++ S FM SKRLGT + + YFV KL++L N +GQL++IQ LGF+ S +F+ +V+G + T FPRV C + I+ +GV+NNY+ QCVL NMLNEKIY FLW W+ +V T I+I LW ++ R +I FL+ Y + K+ + FI FLRHDG F++ M++ N GDLI +++V+ LW+IY +Y N + + Sbjct: 1 MVANTLLDLIKSHKVTDYQGLEDIGDKISFQISVIIYIICGFIVTSKTYILKPLSCYTAISPTGSNFDGYLRNYCWITGTVPWVPGDKFP--QVGDDMKLDDSLKKINYYQWVPFVLALQCIMFYLPRLFWQLMSYNKIGIDLELIFKDASSASNDDEAARKKKAKGIAKNLANVFFFHRDYKYGTWANFRRKIFKFASFFMMSKRLGTWLTYWYFVMKLMFLANAVGQLYLIQRFLGFHGNNIFETSRIFFDSLVNGVQWTTSRLFPRVTVCSIDNIKLLGVENNYITQCVLSQNMLNEKIYMFLWFWLHIVIVVTLITIGLWCKKIIFLGSRAEFIKKFLKNHEVYRKSKRDSLDNFIQTFLRHDGSFIIMMMTMNCGDLITSHVVSELWEIYQSEYANSDTSSE 405 The following BLAST results are available for this feature:
BLAST of Innexin vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 0
BLAST of Innexin vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of Innexin vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of Innexin vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 0
BLAST of Innexin vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 0
BLAST of Innexin vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 0
BLAST of Innexin vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of Innexin vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Innexin vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 0
BLAST of Innexin vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 0
BLAST of Innexin vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 0
BLAST of Innexin vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 0
BLAST of Innexin vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 0
BLAST of Innexin vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30028531 ID=SMED30028531|Name=Innexin|organism=Schmidtea mediterranea sexual|type=transcript|length=1571bpback to top protein sequence of SMED30028531-orf-1 >SMED30028531-orf-1 ID=SMED30028531-orf-1|Name=SMED30028531-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=438bp MVANEFFSLINRLNAVHNYGLEDLADKMSSIFSVLILSVCVSIVTIKSYVback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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