slc22a-3

Overview


Name	slc22a-3 (AKN21551.1)
Smed ID	SMED30028480
Length (bp)	1868

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of slc22a-3 (SMED30028480) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for slc22a-3 (SMED30028480) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30028480

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 4

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication
protonephridia	SMED30028480	SMESG000031472.1	dd_Smed_v4_11135_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
parenchymal cell	SMED30028480	SMESG000031472.1	dd_Smed_v4_11135_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
head region	SMED30028480	SMESG000031472.1	dd_Smed_v6_11135_0_1	dd_Smed_v6	PMID:28171748 Stückemann et al., 2017
proximal tubule	SMED30028480	SMESG000031472.1	Smed-slc22a-3	smed_ncbi_20200123	PMID:21828097 Rink et al., 2011

Note: Hover over icons to view figure legend

Homology

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BLAST of slc22a-3 vs. Ensembl Human
Match: SLC22A7 (solute carrier family 22 member 7 [Source:HGNC Symbol;Acc:HGNC:10971])

HSP 1 Score: 176.022 bits (445), Expect = 2.372e-47
Identity = 139/536 (25.93%), Postives = 240/536 (44.78%), Query Frame = 3

Query:  228 MDPEKCLDELGGKNIWILKWFLLISFMKSLPCVFSMYSFQFTGVKPDSFHCALP--------PNVSRESMIPKERTGDKWEFSSCNQF-------------------QSQDNSTIIPCQNGYNYTMKYFTSSIVTEWDLVCDRAILNALATSSFFVMSFFGAIISCSIADRFGRKVVLITAFMCLNLCEFAQTYITSIYVLIVFKLLAGIFQQGCFISGFTMTIELFSLRNRSNACLADTFSWTXXXXXXXXXXXXXRDWRNYFFWTSITMLPFCLVFYHLPESIRWMMAKDQTKNAQILLKTATLYSNPPLPEKTF--ENYDKYKRKQESEKLPHYNVLHIFRETLLLRYQLINSFVWFTTAMTYYGVQVKVVEIG-NPFLNFFLSSLVEIPANILCFPIANKYGRKITIGLTNFLVGFSLFMGYILWKYLDSPWPAIIVFLVGKMLNTGIFNLIFMHVSEFFPTTLRTTAVGMSSSCARIGASFGAMIFQITLYHDSIAFVIVIGCCLLTGVLVFCLPETYRKKMPTSIEEIKQ 1745
            M  E+ L+++GG   + L+   L++  + L  +  +       V   +  CALP         +V  E+ +P+E  G     SSC +F                   + +D    +PC  G+ Y    F+S+I TEWDLVC++  LN  A++ FF     GA+    ++DRFGR+ +L+ A++   +   A     S  +  + + L G    G  I    + +E   + +R+ A +  +  WT    +L +  Y IRDWR      ++   P  L  + +PES RW++ +   K A   L      +  P+ E +F  E   K    +   + P Y  L +FR   L    L    VWF    +YYG+ + V  +G N +    L   VE+P+ +L +      GR++T   T  L+G +L  G  L    D    + ++ ++GK  +   F   ++  SE +PT LR T +G+++   R+G S   +   +     S+  +   G  LL       LPET + ++P +I+++++
Sbjct:    1 MGFEELLEQVGGFGPFQLRNVALLALPRVLLPLHFLLPIFLAAVP--AHRCALPGAPANFSHQDVWLEAHLPREPDGT---LSSCLRFAYPQALPNTTLGEERQSRGELEDEPATVPCSQGWEYDHSEFSSTIATEWDLVCEQKGLNRAASTFFFAGVLVGAVAFGYLSDRFGRRRLLLVAYVSTLVLGLASAASVSYVMFAITRTLTGSALAGFTIIVMPLELEWLDVEHRTVAGVLSSTFWTGGVMLLALVGYLIRDWRWLLLAVTLPCAPGILSLWWVPESARWLLTQGHVKEAHRYLLHCARLNGRPVCEDSFSQEAVSKVAAGERVVRRPSY--LDLFRTPRLRHISLCCVVVWFGVNFSYYGLSLDVSGLGLNVYQTQLLFGAVELPSKLLVYLSVRYAGRRLTQAGT--LLGTALAFGTRLLVSSDMKSWSTVLAVMGKAFSEAAFTTAYLFTSELYPTVLRQTGMGLTALVGRLGGSLAPLAALLDGVWLSLPKLTYGGIALLAAGTALLLPETRQAQLPETIQDVER 527

[Close]

BLAST of slc22a-3 vs. Ensembl Human
Match: SLC22A7 (solute carrier family 22 member 7 [Source:HGNC Symbol;Acc:HGNC:10971])

HSP 1 Score: 175.637 bits (444), Expect = 3.515e-47
Identity = 138/533 (25.89%), Postives = 239/533 (44.84%), Query Frame = 3

Query:  237 EKCLDELGGKNIWILKWFLLISFMKSLPCVFSMYSFQFTGVKPDSFHCALP--------PNVSRESMIPKERTGDKWEFSSCNQF-------------------QSQDNSTIIPCQNGYNYTMKYFTSSIVTEWDLVCDRAILNALATSSFFVMSFFGAIISCSIADRFGRKVVLITAFMCLNLCEFAQTYITSIYVLIVFKLLAGIFQQGCFISGFTMTIELFSLRNRSNACLADTFSWTXXXXXXXXXXXXXRDWRNYFFWTSITMLPFCLVFYHLPESIRWMMAKDQTKNAQILLKTATLYSNPPLPEKTF--ENYDKYKRKQESEKLPHYNVLHIFRETLLLRYQLINSFVWFTTAMTYYGVQVKVVEIG-NPFLNFFLSSLVEIPANILCFPIANKYGRKITIGLTNFLVGFSLFMGYILWKYLDSPWPAIIVFLVGKMLNTGIFNLIFMHVSEFFPTTLRTTAVGMSSSCARIGASFGAMIFQITLYHDSIAFVIVIGCCLLTGVLVFCLPETYRKKMPTSIEEIKQ 1745
            E+ L+++GG   + L+   L++  + L  +  +       V   +  CALP         +V  E+ +P+E  G     SSC +F                   + +D    +PC  G+ Y    F+S+I TEWDLVC++  LN  A++ FF     GA+    ++DRFGR+ +L+ A++   +   A     S  +  + + L G    G  I    + +E   + +R+ A +  +  WT    +L +  Y IRDWR      ++   P  L  + +PES RW++ +   K A   L      +  P+ E +F  E   K    +   + P Y  L +FR   L    L    VWF    +YYG+ + V  +G N +    L   VE+P+ +L +      GR++T   T  L+G +L  G  L    D    + ++ ++GK  +   F   ++  SE +PT LR T +G+++   R+G S   +   +     S+  +   G  LL       LPET + ++P +I+++++
Sbjct:    4 EELLEQVGGFGPFQLRNVALLALPRVLLPLHFLLPIFLAAVP--AHRCALPGAPANFSHQDVWLEAHLPREPDGT---LSSCLRFAYPQALPNTTLGEERQSRGELEDEPATVPCSQGWEYDHSEFSSTIATEWDLVCEQKGLNRAASTFFFAGVLVGAVAFGYLSDRFGRRRLLLVAYVSTLVLGLASAASVSYVMFAITRTLTGSALAGFTIIVMPLELEWLDVEHRTVAGVLSSTFWTGGVMLLALVGYLIRDWRWLLLAVTLPCAPGILSLWWVPESARWLLTQGHVKEAHRYLLHCARLNGRPVCEDSFSQEAVSKVAAGERVVRRPSY--LDLFRTPRLRHISLCCVVVWFGVNFSYYGLSLDVSGLGLNVYQTQLLFGAVELPSKLLVYLSVRYAGRRLTQAGT--LLGTALAFGTRLLVSSDMKSWSTVLAVMGKAFSEAAFTTAYLFTSELYPTVLRQTGMGLTALVGRLGGSLAPLAALLDGVWLSLPKLTYGGIALLAAGTALLLPETRQAQLPETIQDVER 527

[Close]

BLAST of slc22a-3 vs. Ensembl Human
Match: SLC22A7 (solute carrier family 22 member 7 [Source:HGNC Symbol;Acc:HGNC:10971])

HSP 1 Score: 171.4 bits (433), Expect = 1.544e-45
Identity = 138/535 (25.79%), Postives = 239/535 (44.67%), Query Frame = 3

Query:  237 EKCLDELGGKNIWILKWFLLISFMKSLPCVFSMYSFQFTGVKPDSFHCALP--------PNVSRESMIPKERTGDKWEFSSCNQF-------------------QSQDNSTIIPCQNGYNYTMKYFTSSIVTE--WDLVCDRAILNALATSSFFVMSFFGAIISCSIADRFGRKVVLITAFMCLNLCEFAQTYITSIYVLIVFKLLAGIFQQGCFISGFTMTIELFSLRNRSNACLADTFSWTXXXXXXXXXXXXXRDWRNYFFWTSITMLPFCLVFYHLPESIRWMMAKDQTKNAQILLKTATLYSNPPLPEKTF--ENYDKYKRKQESEKLPHYNVLHIFRETLLLRYQLINSFVWFTTAMTYYGVQVKVVEIG-NPFLNFFLSSLVEIPANILCFPIANKYGRKITIGLTNFLVGFSLFMGYILWKYLDSPWPAIIVFLVGKMLNTGIFNLIFMHVSEFFPTTLRTTAVGMSSSCARIGASFGAMIFQITLYHDSIAFVIVIGCCLLTGVLVFCLPETYRKKMPTSIEEIKQ 1745
            E+ L+++GG   + L+   L++  + L  +  +       V   +  CALP         +V  E+ +P+E  G     SSC +F                   + +D    +PC  G+ Y    F+S+I TE  WDLVC++  LN  A++ FF     GA+    ++DRFGR+ +L+ A++   +   A     S  +  + + L G    G  I    + +E   + +R+ A +  +  WT    +L +  Y IRDWR      ++   P  L  + +PES RW++ +   K A   L      +  P+ E +F  E   K    +   + P Y  L +FR   L    L    VWF    +YYG+ + V  +G N +    L   VE+P+ +L +      GR++T   T  L+G +L  G  L    D    + ++ ++GK  +   F   ++  SE +PT LR T +G+++   R+G S   +   +     S+  +   G  LL       LPET + ++P +I+++++
Sbjct:    4 EELLEQVGGFGPFQLRNVALLALPRVLLPLHFLLPIFLAAVP--AHRCALPGAPANFSHQDVWLEAHLPREPDGT---LSSCLRFAYPQALPNTTLGEERQSRGELEDEPATVPCSQGWEYDHSEFSSTIATESQWDLVCEQKGLNRAASTFFFAGVLVGAVAFGYLSDRFGRRRLLLVAYVSTLVLGLASAASVSYVMFAITRTLTGSALAGFTIIVMPLELEWLDVEHRTVAGVLSSTFWTGGVMLLALVGYLIRDWRWLLLAVTLPCAPGILSLWWVPESARWLLTQGHVKEAHRYLLHCARLNGRPVCEDSFSQEAVSKVAAGERVVRRPSY--LDLFRTPRLRHISLCCVVVWFGVNFSYYGLSLDVSGLGLNVYQTQLLFGAVELPSKLLVYLSVRYAGRRLTQAGT--LLGTALAFGTRLLVSSDMKSWSTVLAVMGKAFSEAAFTTAYLFTSELYPTVLRQTGMGLTALVGRLGGSLAPLAALLDGVWLSLPKLTYGGIALLAAGTALLLPETRQAQLPETIQDVER 529

[Close]

BLAST of slc22a-3 vs. Ensembl Human
Match: SLC22A5 (solute carrier family 22 member 5 [Source:HGNC Symbol;Acc:HGNC:10969])

HSP 1 Score: 164.081 bits (414), Expect = 5.194e-43
Identity = 109/423 (25.77%), Postives = 218/423 (51.54%), Query Frame = 3

Query:  498 CQNGYNYTMKYFTSSIVTEWDLVCDRAILNALATSSFFVMSFFGAIISCSIADRFGRKVVLITAFMCLNLCEFAQTYITSIYVLIVFKLLAGIFQQGCFISGFTMTIELFSLRNRS-----NACLADTFSWTXXXXXXXXXXXXXRDWRNYFFWTSITMLPFCLVFYHLPESIRWMMAKDQTKNAQILLKTATLYSNPPLPEKTF---ENYDKYKRKQESEKLPHYNVLHIFRETLLLRYQLINSFVWFTTAMTYYGVQVKVVEI-GNPFLNFFLSSLVEIPANILCFPIANKYGRKITIGLTNFLVGFSLFMGYILWKYLDSPWPAIIVFLVGKMLNTGIFNLIFMHVSEFFPTTLRTTAVGMSSSCARIGASFGAMIFQITLYHDSIAFVIVIGCCLLTGVLVFCLPETYRKKMPTSIEEI 1739
            C +G+ ++   + S+IVTEW+LVC+      L  S FFV    G+ IS  ++DRFGRK VL           F Q +  +  + +V  +L G+ Q   +++ F +  E+     R        C+   F +     +L ++ YFIRDWR      ++  +    +++ +PES RW++++ + + A+++++ A   +   +P   F   E  D   +KQ+S     +N+L + R   +    +++  +W T ++ Y+G+ +    + G+ F+N FLS++VE+PA +L + +     R+ ++    FL G  L    ++    D  + A ++ +VGK   T  F++++++ +E +PT +R   VG+SS+ +R+G+        +  Y   + ++++    +LT +L   LPE++   +P +I+++
Sbjct:  113 CLDGWEFSQDVYLSTIVTEWNLVCEDDWKAPLTISLFFVGVLLGSFISGQLSDRFGRKNVLFVTMGMQTGFSFLQIFSKNFEMFVVLFVLVGMGQISNYVAAFVLGTEILGKSVRIIFSTLGVCIFYAFGY----MVLPLFAYFIRDWRMLLVALTMPGVLCVALWWFIPESPRWLISQGRFEEAEVIIRKAAKANGIVVPSTIFDPSELQDLSSKKQQS-----HNILDLLRTWNIRMVTIMSIMLWMTISVGYFGLSLDTPNLHGDIFVNCFLSAMVEVPAYVLAWLLLQYLPRRYSMATALFLGGSVLLFMQLVPP--DLYYLATVLVMVGKFGVTAAFSMVYVYTAELYPTVVRNMGVGVSSTASRLGSILSPYFVYLGAYDRFLPYILMGSLTILTAILTLFLPESFGTPLPDTIDQM 524

[Close]

BLAST of slc22a-3 vs. Ensembl Human
Match: SLC22A16 (solute carrier family 22 member 16 [Source:HGNC Symbol;Acc:HGNC:20302])

HSP 1 Score: 154.836 bits (390), Expect = 7.927e-40
Identity = 122/493 (24.75%), Postives = 217/493 (44.02%), Query Frame = 3

Query:  309 KSLPCVFSMYSFQFTGVKPDSFHCALPPNVSRESMIPKERTGDKWEFSSCNQFQSQDNSTI----------IPCQNGYNYTMKYFTSSIVTEWDLVCDRAILNALATSSFFVMSFFGAIISCSIADRFGRKVVLITAFMCLNLCEFAQTYITSIYVLIVFKLLAGIFQQGCFISGFTMTIELFSLRNRSNACLADTFSWTXXXXXXXXXXXXXRDWRNYFFWTSITMLPFCLVFYHLPESIRWMMAKDQTKNAQILLKTATLY---SNPPLPEKTFENYDKYKRKQESEKLPHYNVLHIFRETLLLRYQLINSFVWFTTAMTYYGVQVKVVEI-GNPFLNFFLSSLVEIPANILCFPIANKYGRKITIGLTNFLVGFSLFMGYILWKYLDSPWPAIIVFLVGKMLNTGIFNLIFMHVSEFFPTTLRTTAVGMSSSCARIGASFGAMIFQITLYHDSIAFVIVIGCCLLTGVLVFCLPETYRKKMPTSIEEIKQ 1745
            +++ C     +  F GV P   H   PP           + G+ WE S C++ + ++ S++           PC +GY Y    + S+ VT+W+LVCDR  L  L    F      G++     +DR GR+VVL      + L   A  +    Y  +  +    +   G  + GF   +E   +++R+ A +     +   + ++ +  Y +R W  Y    S   +PF L  + LPE+  W++++ + + AQ ++     +   S+  L E    +         +E   H N+ ++F    + +  L    +WFT ++ +Y   +  V + GN +LN FL  +VEIPA        +K GR+  +  + F    +L  G ++          ++  +VGK      F LI+++ +E +PT +R+ AVG  S   R+ +        ++     I  + V    LL+GVL   LPET  K++ T+ EE  +
Sbjct:   28 QNISCGIHYLASVFMGVTPH--HVCRPPG--------NLQNGEIWELSRCSRNKRENTSSLGYEYTGSKKEFPCVDGYIYDQNTWKSTAVTQWNLVCDRKWLAMLIQPLFMFGVLLGSVTFGYFSDRLGRRVVLWATSSSMFLFGIAAAFAVDYYTFMAARFFLAMVASGYLVVGFVYVMEFIGMKSRTWASVHLHSFFAVGTLLVALTGYLVRTWWLYQMILSTVTVPFILCCWVLPETPFWLLSEGRYEEAQKIVDIMAKWNRASSCKLSELLSLDLQGPVSNSPTEVQKH-NLSYLFYNWSITKRTLTVWLIWFTGSLGFYSFSLNSVNLGGNEYLNLFLLGVVEIPAYTFVCIAMDKVGRRTVLAYSLFCS--ALACGVVMVIPQKHYILGVVTAMVGKFAIGAAFGLIYLYTAELYPTIVRSLAVGSGSMVCRLASILAPFSVDLSSIWIFIPQLFVGTMALLSGVLTLKLPETLGKRLATTWEEAAK 507

[Close]

BLAST of slc22a-3 vs. Ensembl Celegans
Match: oct-1 (Organic cation transporter 1 [Source:UniProtKB/Swiss-Prot;Acc:Q9U539])

HSP 1 Score: 167.933 bits (424), Expect = 1.127e-44
Identity = 136/535 (25.42%), Postives = 243/535 (45.42%), Query Frame = 3

Query:  246 LDELGGKNIWILKWFLLISFMKSLPCVFSMYSFQFTGVKPDSFHCALPPNVSRESMIPKERTGDKWEFSSCNQFQS-----------------QDNSTIIPCQNGYNYTMKYFTSSIVTEWDLVCDRAILNALATSSFFVMSFFGAIISCSIADRFGRKVVLITAFMCLNLCEFAQTYITSIYVLIVFKLLAGIFQQGCFISGFTMTIELFSLRNRSNACLADTFSWTXXXXXXXXXXXXXRDWRNYFFWTSITMLPFCLVFYHLPESIRWMMAKDQTKNAQILLKTATLY---SNPPLPE--KTFENYDKYKRKQESEKLPHYNVLHIFRETLLLRYQLINSFVWFTTAMTYYGVQVKVVEIG-NPFLNFFLSSLVEIPANILCFPIANKYGRKITIGLTNFLVGF----SLFM--GYILWKYLDSPWPAIIVFLVGKMLNTGIFNLIFMHVSEFFPTTLRTTAVGMSSSCARIGASFGAMIFQITLYHDSIAFVIVIGCCLLTGVLVFCLPETYRKKMPTSIEEIKQWVAHKP 1763
            L+++G    + + +F +I    SLP  FS ++  F    P    C +P    +E + P   T D  +  SC Q+                    D  +++PCQNG++Y    +  S+VTE++LVCD+     ++T+SF+V SF G  +   +AD+FGR+         L +C  A ++   I   I+ +   G+     F   F + +E      R  + L  +  +  +  +L +   FIR WR   F+ +     + + ++ LPES RW ++  +  +A+  LK        SN  + E   + +N+     ++E+++   +NV  +F+   L R  LI +++W   A+ Y G+ + V  +  + + +F ++  VE+P   + +P+    GR+ T+  T  + G     ++FM  GY        PW       +GK      F +I++   E +PT +R   +GMSS  A  G      I  +      +  +I+    L  G+L F LPET    +P +IE+ + +   KP
Sbjct:   13 LEQVGNYGTYQIVFFFIICLPTSLPSAFSAFNIPFVVGNPPH-TCHIPEG--KEYLRP--LTNDT-QILSCKQYNETQINVFRAFTSAPVDTYSDRISLVPCQNGWDYDNSTYLDSLVTEFNLVCDQQAWIEISTTSFYVGSFIGNCLFGYVADKFGRRRSFFVILTVLIVCGTASSFAKDIESFIILRFFTGLAFPALFQIPFIICMEFMGNSGRIFSGLMTSLFFGAAMALLGVVAMFIRRWRQLTFFCNAPFAFYIIYYFFLPESPRWSVSVGKWADAKKQLKKIAKMNGKSNVDVDELVDSMKNHQNAAEEKETKR--SHNVTDLFKTPNLRRKTLIVTYIWVMNAIIYNGLTLNVSNLPVDDYWSFIINGAVELPGYFVVWPLLQCAGRRWTLAATMIVCGIGCVSAMFMPDGY--------PWLVASASFIGKFGVGSGFAVIYIFAGELYPTVVRAIGMGMSSMVAGSGLLLAPHIVNLGKIVKILPLLIMGLMALSAGILTFFLPETLGAPLPMTIEDAENF-GKKP 530

[Close]

Query:  246 LDELGGKNIWILKWFLLISFMKSLPCVFSMYSFQFTGVKPDSFHCALPPNVSRESMIPKERTGDKWEFSSCNQFQS-----------------QDNSTIIPCQNGYNYTMKYFTSSIVTEWDLVCDRAILNALATSSFFVMSFFGAIISCSIADRFGRKVVLITAFMCLNLCEFAQTYITSIYVLIVFKLLAGIFQQGCFISGFTMTIELFSLRNRSNACLADTFSWTXXXXXXXXXXXXXRDWRNYFFWTSITMLPFCLVFYHLPESIRWMMAKDQTKNAQILLKTATLY---SNPPLPE--KTFENYDKYKRKQESEKLPHYNVLHIFRETLLLRYQLINSFVWFTTAMTYYGVQVKVVEIG-NPFLNFFLSSLVEIPANILCFPIANKYGRKITIGLTNFLVGF----SLFM--GYILWKYLDSPWPAIIVFLVGKMLNTGIFNLIFMHVSEFFPTTLRTTAVGMSSSCARIGASFGAMIFQITLYHDSIAFVIVIGCCLLTGVLVFCLPETYRKKMPTSIEEIKQWVAHKP 1763
            L+++G    + + +F +I    SLP  FS ++  F    P    C +P    +E + P   T D  +  SC Q+                    D  +++PCQNG++Y    +  S+VTE++LVCD+     ++T+SF+V SF G  +   +AD+FGR+         L +C  A ++   I   I+ +   G+     F   F + +E      R  + L  +  +  +  +L +   FIR WR   F+ +     + + ++ LPES RW ++  +  +A+  LK        SN  + E   + +N+     ++E+++   +NV  +F+   L R  LI +++W   A+ Y G+ + V  +  + + +F ++  VE+P   + +P+    GR+ T+  T  + G     ++FM  GY        PW       +GK      F +I++   E +PT +R   +GMSS  A  G      I  +      +  +I+    L  G+L F LPET    +P +IE+ + +   KP
Sbjct:   13 LEQVGNYGTYQIVFFFIICLPTSLPSAFSAFNIPFVVGNPPH-TCHIPEG--KEYLRP--LTNDT-QILSCKQYNETQINVFRAFTSAPVDTYSDRISLVPCQNGWDYDNSTYLDSLVTEFNLVCDQQAWIEISTTSFYVGSFIGNCLFGYVADKFGRRRSFFVILTVLIVCGTASSFAKDIESFIILRFFTGLAFPALFQIPFIICMEFMGNSGRIFSGLMTSLFFGAAMALLGVVAMFIRRWRQLTFFCNAPFAFYIIYYFFLPESPRWSVSVGKWADAKKQLKKIAKMNGKSNVDVDELVDSMKNHQNAAEEKETKR--SHNVTDLFKTPNLRRKTLIVTYIWVMNAIIYNGLTLNVSNLPVDDYWSFIINGAVELPGYFVVWPLLQCAGRRWTLAATMIVCGIGCVSAMFMPDGY--------PWLVASASFIGKFGVGSGFAVIYIFAGELYPTVVRAIGMGMSSMVAGSGLLLAPHIVNLGKIVKILPLLIMGLMALSAGILTFFLPETLGAPLPMTIEDAENF-GKKP 530

[Close]

BLAST of slc22a-3 vs. Ensembl Celegans
Match: oct-1 (Organic cation transporter 1 [Source:UniProtKB/Swiss-Prot;Acc:Q9U539])

HSP 1 Score: 167.933 bits (424), Expect = 1.586e-44
Identity = 136/535 (25.42%), Postives = 243/535 (45.42%), Query Frame = 3

Query:  246 LDELGGKNIWILKWFLLISFMKSLPCVFSMYSFQFTGVKPDSFHCALPPNVSRESMIPKERTGDKWEFSSCNQFQS-----------------QDNSTIIPCQNGYNYTMKYFTSSIVTEWDLVCDRAILNALATSSFFVMSFFGAIISCSIADRFGRKVVLITAFMCLNLCEFAQTYITSIYVLIVFKLLAGIFQQGCFISGFTMTIELFSLRNRSNACLADTFSWTXXXXXXXXXXXXXRDWRNYFFWTSITMLPFCLVFYHLPESIRWMMAKDQTKNAQILLKTATLY---SNPPLPE--KTFENYDKYKRKQESEKLPHYNVLHIFRETLLLRYQLINSFVWFTTAMTYYGVQVKVVEIG-NPFLNFFLSSLVEIPANILCFPIANKYGRKITIGLTNFLVGF----SLFM--GYILWKYLDSPWPAIIVFLVGKMLNTGIFNLIFMHVSEFFPTTLRTTAVGMSSSCARIGASFGAMIFQITLYHDSIAFVIVIGCCLLTGVLVFCLPETYRKKMPTSIEEIKQWVAHKP 1763
            L+++G    + + +F +I    SLP  FS ++  F    P    C +P    +E + P   T D  +  SC Q+                    D  +++PCQNG++Y    +  S+VTE++LVCD+     ++T+SF+V SF G  +   +AD+FGR+         L +C  A ++   I   I+ +   G+     F   F + +E      R  + L  +  +  +  +L +   FIR WR   F+ +     + + ++ LPES RW ++  +  +A+  LK        SN  + E   + +N+     ++E+++   +NV  +F+   L R  LI +++W   A+ Y G+ + V  +  + + +F ++  VE+P   + +P+    GR+ T+  T  + G     ++FM  GY        PW       +GK      F +I++   E +PT +R   +GMSS  A  G      I  +      +  +I+    L  G+L F LPET    +P +IE+ + +   KP
Sbjct:   30 LEQVGNYGTYQIVFFFIICLPTSLPSAFSAFNIPFVVGNPPH-TCHIPEG--KEYLRP--LTNDT-QILSCKQYNETQINVFRAFTSAPVDTYSDRISLVPCQNGWDYDNSTYLDSLVTEFNLVCDQQAWIEISTTSFYVGSFIGNCLFGYVADKFGRRRSFFVILTVLIVCGTASSFAKDIESFIILRFFTGLAFPALFQIPFIICMEFMGNSGRIFSGLMTSLFFGAAMALLGVVAMFIRRWRQLTFFCNAPFAFYIIYYFFLPESPRWSVSVGKWADAKKQLKKIAKMNGKSNVDVDELVDSMKNHQNAAEEKETKR--SHNVTDLFKTPNLRRKTLIVTYIWVMNAIIYNGLTLNVSNLPVDDYWSFIINGAVELPGYFVVWPLLQCAGRRWTLAATMIVCGIGCVSAMFMPDGY--------PWLVASASFIGKFGVGSGFAVIYIFAGELYPTVVRAIGMGMSSMVAGSGLLLAPHIVNLGKIVKILPLLIMGLMALSAGILTFFLPETLGAPLPMTIEDAENF-GKKP 547

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BLAST of slc22a-3 vs. Ensembl Celegans
Match: B0252.3 (Putative transporter B0252.3 [Source:UniProtKB/Swiss-Prot;Acc:Q10917])

HSP 1 Score: 130.183 bits (326), Expect = 4.624e-32
Identity = 102/401 (25.44%), Postives = 179/401 (44.64%), Query Frame = 3

Query:  540 SIVTEWDLVCDRAILNALATSSFFVMSFFGAIISCSIADRFGRKVVLITAFMCLNLCEFAQTYITSIYVLIVFKLLAGIFQQGCFISGFTMTIELFSLRNRSNACLADTFSWTXXXXXXXXXXXXXRDWRNYFFWTSITMLPFCLVFYH-LPESIRWMMAKDQTKNAQILLKTATLYSNPPLPEKTFENYDKYKRKQESEKLPHYNVLHIFRETLLLRYQLINSFVWFTTAMTYYGVQVKVVEI-GNPFLNFFLSSLVEIPANILCFPIANKYGRKITIGLTNFLVGFSLFMGYILWKYLDSPWPAIIVFLVGKMLNTGIFNLIFMHVSEFFPTTLRTTAVGMSSSCARIGASFGAMIFQITLYHDSIAFVIVIGCCLLTGVLVFCLPETYRKKMPTSIEE 1736
             +  E+DL  D + L    T+ + V +  G +    +AD +GR  V +   + + +      + TSI +  + +++ GIF     ++G+ +  E   LR R    +     W   +  L +  Y + DWR   F  S+  +   L+ Y  +PES+ ++++  Q +  +  L+          P+      D  + + E+          +++  + + Y L+ +++W      Y+G+      + GN +LNF L SLVE PA I      NKYGRK+ I  T+ + G S F+G +L     S    I  +L+GK   +  F  I+M  SE FPT  R   +G   + +R G      +  +T  H     + +    +  G+L   LPET   K+P++I E
Sbjct:   78 GVADEFDLTGDASWLAESTTTFYMVGNMIGGMFIPPLADHYGRLPVFVATVLLMAVGGMISAFSTSIMMFCIMRMIHGIFYTAAGLAGWVLGYENTPLRLRFFTSVYFGVMWVVGACFLGLLAYILPDWRYLMFCISVPNIFVALLIYMTVPESLHFLVSSQQNEKIEAWLEKIRG------PKGDISASDIVEDRDENGSSFKTLCREMWKHKMFIVYVLVMTYIWIVDTFIYFGLAFYSTNLAGNLYLNFVLMSLVEAPAYIFSPIFMNKYGRKVLISGTHIIAGLS-FLGIVL----SSEAWHIHFWLLGKFAISCSFMSIYMFASEIFPTDGRNKCIGFCETLSRFGGMLSPYLSHLTAVHALAPAITLSLIAVSGGLLTLILPETLNTKLPSTIAE 467

[Close]

BLAST of slc22a-3 vs. Ensembl Celegans
Match: B0252.3 (Putative transporter B0252.3 [Source:UniProtKB/Swiss-Prot;Acc:Q10917])

HSP 1 Score: 129.798 bits (325), Expect = 4.957e-32
Identity = 102/401 (25.44%), Postives = 179/401 (44.64%), Query Frame = 3

Query:  540 SIVTEWDLVCDRAILNALATSSFFVMSFFGAIISCSIADRFGRKVVLITAFMCLNLCEFAQTYITSIYVLIVFKLLAGIFQQGCFISGFTMTIELFSLRNRSNACLADTFSWTXXXXXXXXXXXXXRDWRNYFFWTSITMLPFCLVFYH-LPESIRWMMAKDQTKNAQILLKTATLYSNPPLPEKTFENYDKYKRKQESEKLPHYNVLHIFRETLLLRYQLINSFVWFTTAMTYYGVQVKVVEI-GNPFLNFFLSSLVEIPANILCFPIANKYGRKITIGLTNFLVGFSLFMGYILWKYLDSPWPAIIVFLVGKMLNTGIFNLIFMHVSEFFPTTLRTTAVGMSSSCARIGASFGAMIFQITLYHDSIAFVIVIGCCLLTGVLVFCLPETYRKKMPTSIEE 1736
             +  E+DL  D + L    T+ + V +  G +    +AD +GR  V +   + + +      + TSI +  + +++ GIF     ++G+ +  E   LR R    +     W   +  L +  Y + DWR   F  S+  +   L+ Y  +PES+ ++++  Q +  +  L+          P+      D  + + E+          +++  + + Y L+ +++W      Y+G+      + GN +LNF L SLVE PA I      NKYGRK+ I  T+ + G S F+G +L     S    I  +L+GK   +  F  I+M  SE FPT  R   +G   + +R G      +  +T  H     + +    +  G+L   LPET   K+P++I E
Sbjct:   58 GVADEFDLTGDASWLAESTTTFYMVGNMIGGMFIPPLADHYGRLPVFVATVLLMAVGGMISAFSTSIMMFCIMRMIHGIFYTAAGLAGWVLGYENTPLRLRFFTSVYFGVMWVVGACFLGLLAYILPDWRYLMFCISVPNIFVALLIYMTVPESLHFLVSSQQNEKIEAWLEKIRG------PKGDISASDIVEDRDENGSSFKTLCREMWKHKMFIVYVLVMTYIWIVDTFIYFGLAFYSTNLAGNLYLNFVLMSLVEAPAYIFSPIFMNKYGRKVLISGTHIIAGLS-FLGIVL----SSEAWHIHFWLLGKFAISCSFMSIYMFASEIFPTDGRNKCIGFCETLSRFGGMLSPYLSHLTAVHALAPAITLSLIAVSGGLLTLILPETLNTKLPSTIAE 447

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BLAST of slc22a-3 vs. Ensembl Fly
Match: Balat (gene:FBgn0033778 transcript:FBtr0087815)

HSP 1 Score: 167.548 bits (423), Expect = 3.253e-44
Identity = 127/547 (23.22%), Postives = 231/547 (42.23%), Query Frame = 3

Query:  228 MDPEKCLDELGGKNIWILKWFLLISFMKSLPCVFSMYSFQFTGVKPDSFHCALPP---------NVSRESMIPKERTGDKWEFSSCNQFQSQ-----------------------------DNSTIIPCQNGYNYTMKYFTSSIVTEWDLVCDRAILNALATSSFFVMSFFGAIISCSIADRFGRKVVLITAFMCLNLCEFAQTYITSIYVLIVFKLLAGIFQQGCFISGFTMTIELFSLRNRSNACLADTFSWTXXXXXXXXXXXXXRDWRNYFFWTSITMLPFCLVFYHLPESIRWMMAKDQTKNAQILLKTATLYSNPPLPEKTFENYDK-----YKRKQESEKLPHYNVLHIFRETLLLRYQLINSFVWFTTAMTYYGVQVKVVEI-GNPFLNFFLSSLVEIPANILCFPIANKYGRKITIGLTNFLVGFSLFMGYILWKYLDSPWPAIIVFLVGKMLNTGIFNLIFMHVSEFFPTTLRTTAVGMSSSCARIGASFGAMIFQITLYHDSIAFVIVIGCCLLTGVLVFCLPETYRKKMPTSIEE 1736
            MD ++ L E+G   ++       +    +LPC F  YS  F    P  F C +P           + +   IP+ R G    ++ C+ +                                D + ++PCQ+G++Y    ++S++V EW+LVCDR+ L  LA   F V    G  +   + D +GR+       +   +   A  +  + Y  +  + + G+       S + + IEL     R    +    +++    +L   IY +RDWR      S+ +L     F+ LPES RW+MA  +T+ A  +LK     +   +     E   +        + +S    HY +L +FR   + R  LI + +WF     Y G+      + G+   NFFL+  VE+P  +L +P  + +GR+  + ++  + G +    ++       P   ++++ VGKM  +  F ++ +  SE +PT +R   +  SS  + +G     MI  +      +  +++    +L G     LPET  + +P ++EE
Sbjct:    1 MDFDEVLREVGSFGLYQKVIICSVLLPAALPCAFHAYSQLFIAATPQHF-CRVPELEPWTQDYVQLVKNLSIPRNRNG---AYAECSMYSRNYTDIVRYLEYRPPPDLLRQQAEDLLKLQPDTTQVVPCQHGWHYDKSIYSSTVVQEWNLVCDRSFLVTLALVVFGVGGLLGNYVFGYLVDLWGRRPSFYAYLLLEIIACAASAFAWNYYTWLGLRFVVGLTVPAILASPYVLAIELVGPERRVFCTIVSNIAYSLGLVVLAGVIYIVRDWRELSLAVSMPLLMLFSCFFVLPESPRWLMAVGKTRRAIKILKVMARVNGVRVNRDFVERLQRKLVITRAAETKSSMTTHYGILDLFRGPNMRRKTLIITLIWFANTSVYVGLSYYAPALGGDEIWNFFLAGAVELPTYLLLWPGLSYFGRRWILFISMLVGGVACVATFLY------PDITLLLYCVGKMGISSSFVVLPLMASELYPTVVRGLGMSFSSVISMVGPIVIPMINHMGQQMLVLPLIVMGALLILGGFASLLLPETRNRNLPQTLEE 537

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BLAST of slc22a-3 vs. Ensembl Fly
Match: CG6126 (gene:FBgn0038407 transcript:FBtr0083278)

HSP 1 Score: 152.525 bits (384), Expect = 2.613e-39
Identity = 124/455 (27.25%), Postives = 203/455 (44.62%), Query Frame = 3

Query:  408 SMIPKERTGDKWEFSSCNQFQ--SQDNSTIIPCQNGYNYTMKYFTSSIVTEWDLVCDRAILNALATSSFFVMSFFGAIISCSIADRFGRKVVLITAFMCLNLCEFAQTYITSIYVLIVFKLLAGIF-QQGCFISGFTMTIELFSLRNRS--NACLADTFSWTXXXXXXXXXXXXXRDWRNYFFWTSITMLPFCLVFYH---LPESIRWMMAKDQTKNAQILLKTATLYSNPPLPEKTFENYDKYKRKQESEKLPHYNVLHIFRETLLLRYQLIN-SFVWFTTAMTYYGVQVKVVEI-GNPFLNFFLSSLVEIPANILCFPIANKYGRKITIGLTNFLVGF--SLFMGYILWKYLDSPWPAIIVFLVGKMLNTGIFNLIFMHVSEFFPTTLRTTAVGMSSSCARIGASFGAMIFQITLYHDSIAFVIVIGCCLLTGVLVFCLPETYRKKMPTSIEE 1736
            + IP +  G   E  SC  F   S   +T I C+  Y Y   Y+ +S   +W+ VCDR  + A+  + F +  F GA+    +AD+ GRK V   + +   +      +I   +  +V + L GI    G +I GF +T+EL     R+         F+           +   R W    +      L  CL   H   L ES RW+  + +   A  ++      +   +P        K K++  +E+     +  +FR T  LR + +N    WF  ++ YYG+ +   ++ GNP+L  F+  LVE P+ I    + ++ GR+ +I  T  L G    +   YI      S      V + GK+L  G F +I+ + +E FPT +R +A+G+ S CAR+  +   +I  +  +   I  V+     L++G  V  LPET  + MP SIE+
Sbjct:   75 AAIPLKPNG---ELESCLMFDPSSPGTNTTINCER-YVYDTTYYKTSRTIDWNFVCDRRWMGAIVQTVFMLGVFTGAVTLGGLADKVGRKTVFCWSALFQLIIGVGVAFIPEYFSFMVARYLLGIVGSAGAYICGFVLTMELVGPTKRTVCGITFQAVFAGGIMLVAGWGALIPDRQWLQVIY-----GLHGCLFLGHWWWLDESPRWLWMQGRAAEAVDIVAKGLRINGSGIPVDKEYYVQKAKQQAAAEEKSSAGLSDLFR-TPNLRMKTLNVCLCWFANSLVYYGLSLSAGKLYGNPYLILFIMGLVEFPSYITIVFVLDRLGRR-SITSTLMLGGGLCCIVAAYIAQGSTTS----TAVVMAGKLLIAGSFAVIYNYSAELFPTVVRNSAMGLGSMCARLSGALTPLITLLDSFDPKIPAVLFGVVALISGFWVMFLPETMNQPMPESIED 514

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BLAST of slc22a-3 vs. Ensembl Fly
Match: Orct (gene:FBgn0019952 transcript:FBtr0334870)

HSP 1 Score: 152.14 bits (383), Expect = 3.449e-39
Identity = 128/504 (25.40%), Postives = 222/504 (44.05%), Query Frame = 3

Query:  306 MKSLPCVFSMYSFQFTGVKPDSFHCALP-PNVSRESMIPKERTGDKWEFSSCNQF-----QSQDNSTIIPCQN------GYNYTMKYFTSSIVTEWDLVCDRAILNALATSSFFVMSFFGAIISCSIADRFGRKVVLITAFMCLNLCEFAQTYITSIYVLIVFKLLAGIFQQGCFISGFTMTIELFSLRNRSNACLADTFSWTXXXXXXXXXXXXXRDWRNYFFWTSITMLPFCLVFYHLPESIRWMMAKDQTKNAQILLKTATLYSNPPLPEKTFENY-----DKYKRKQESEKLPHYNVLHIFRETLLLRYQLINSFVWFTTAMTYYGVQVKVVEI-GNPFLNFFLSSLVEIPANILCFPIANKYGRKITIGLTNFLVGFSLFMGYILWKYLDSPWPAIIVFLVGKMLNTGIFNLIFMHVSEFFPTTLRTTAVGMSSSCARIGASFGAMIFQITLYHDSIAFVIVIGCCLLTGVLVFCLPETYRKKMPTSIEEIKQWVAHKP 1763
            + ++ C F   +  F   KPD F CALP  N S   + P        E   C+ +     +   N +I    N       Y Y    + +S VTEW+LVC R++L+A + S F +    G++I   ++D+ GRK     + +   +           +   + +++ G    G F+  + + +E+     R  A +A    ++    +   + YFI DWR      ++  L F   ++ +PES RW++ K +   A ++++ A   +   +P + +E       +K K+ + +   P   V  + R   L R  L+  F WF  +  YYG+      + GN  +NF +S  VEIP   L     N++GR+  +  T  + G SL     ++   D  W  +   ++GK+  T  +  I++  +E FPT +R   +G SS  AR+G      +  +      +  +I     L  G+L   LPET  K MP +IE+ + +   KP
Sbjct:   26 LPAIVCAFHKLAGVFLLAKPD-FRCALPYENGSIYELSPHLWNLSYPENERCSYYDVDYTEEYLNGSIPRSSNETKTCSSYVYDRSKYLNSAVTEWNLVCSRSLLSATSDSLFMLGVLLGSLIFGQMSDKLGRKPTFFASLVLQLIFGVLAAVAPEYFSYTISRMIVGATTSGVFLVAYVIALEMVGSSYRLFAGVAMQMFFSVGFMLTAGFAYFIHDWRWLQIAITLPGLLFLCYYWIIPESARWLLMKGRKDEAFVIIEKAAKENKVEVPNEIYEQLVDEVAEKKKQDEMAASQPAATVFDLLRYPNLRRKTLLIFFDWFVNSGVYYGLSWNTNNLGGNQLVNFMISGAVEIPGYTLLLFTLNRWGRRSILCGTMMVAGISLLA--TIFVPSDMNWLIVACAMIGKLAITSSYGTIYIFSAEQFPTVVRNVGLGASSMVARVGGILAPYLKLLGEIWRPLPLIICGALSLTAGLLSLLLPETLNKPMPETIEDGENF-GKKP 525

[Close]

BLAST of slc22a-3 vs. Ensembl Fly
Match: Orct (gene:FBgn0019952 transcript:FBtr0084599)

HSP 1 Score: 152.14 bits (383), Expect = 3.449e-39
Identity = 128/504 (25.40%), Postives = 222/504 (44.05%), Query Frame = 3

Query:  306 MKSLPCVFSMYSFQFTGVKPDSFHCALP-PNVSRESMIPKERTGDKWEFSSCNQF-----QSQDNSTIIPCQN------GYNYTMKYFTSSIVTEWDLVCDRAILNALATSSFFVMSFFGAIISCSIADRFGRKVVLITAFMCLNLCEFAQTYITSIYVLIVFKLLAGIFQQGCFISGFTMTIELFSLRNRSNACLADTFSWTXXXXXXXXXXXXXRDWRNYFFWTSITMLPFCLVFYHLPESIRWMMAKDQTKNAQILLKTATLYSNPPLPEKTFENY-----DKYKRKQESEKLPHYNVLHIFRETLLLRYQLINSFVWFTTAMTYYGVQVKVVEI-GNPFLNFFLSSLVEIPANILCFPIANKYGRKITIGLTNFLVGFSLFMGYILWKYLDSPWPAIIVFLVGKMLNTGIFNLIFMHVSEFFPTTLRTTAVGMSSSCARIGASFGAMIFQITLYHDSIAFVIVIGCCLLTGVLVFCLPETYRKKMPTSIEEIKQWVAHKP 1763
            + ++ C F   +  F   KPD F CALP  N S   + P        E   C+ +     +   N +I    N       Y Y    + +S VTEW+LVC R++L+A + S F +    G++I   ++D+ GRK     + +   +           +   + +++ G    G F+  + + +E+     R  A +A    ++    +   + YFI DWR      ++  L F   ++ +PES RW++ K +   A ++++ A   +   +P + +E       +K K+ + +   P   V  + R   L R  L+  F WF  +  YYG+      + GN  +NF +S  VEIP   L     N++GR+  +  T  + G SL     ++   D  W  +   ++GK+  T  +  I++  +E FPT +R   +G SS  AR+G      +  +      +  +I     L  G+L   LPET  K MP +IE+ + +   KP
Sbjct:   26 LPAIVCAFHKLAGVFLLAKPD-FRCALPYENGSIYELSPHLWNLSYPENERCSYYDVDYTEEYLNGSIPRSSNETKTCSSYVYDRSKYLNSAVTEWNLVCSRSLLSATSDSLFMLGVLLGSLIFGQMSDKLGRKPTFFASLVLQLIFGVLAAVAPEYFSYTISRMIVGATTSGVFLVAYVIALEMVGSSYRLFAGVAMQMFFSVGFMLTAGFAYFIHDWRWLQIAITLPGLLFLCYYWIIPESARWLLMKGRKDEAFVIIEKAAKENKVEVPNEIYEQLVDEVAEKKKQDEMAASQPAATVFDLLRYPNLRRKTLLIFFDWFVNSGVYYGLSWNTNNLGGNQLVNFMISGAVEIPGYTLLLFTLNRWGRRSILCGTMMVAGISLLA--TIFVPSDMNWLIVACAMIGKLAITSSYGTIYIFSAEQFPTVVRNVGLGASSMVARVGGILAPYLKLLGEIWRPLPLIICGALSLTAGLLSLLLPETLNKPMPETIEDGENF-GKKP 525

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BLAST of slc22a-3 vs. Ensembl Fly
Match: CG4630 (gene:FBgn0033809 transcript:FBtr0087765)

HSP 1 Score: 138.272 bits (347), Expect = 2.749e-34
Identity = 109/455 (23.96%), Postives = 207/455 (45.49%), Query Frame = 3

Query:  423 ERTGDKWEFSSCNQFQSQDNSTIIPCQNGYNYTMKYFTSSIVTEWDLVCDRAILN-ALATSSFFVMSFFGAIISCSIADRFGRKVVLITAFMCLNLCEFAQTYITSIYVLIVFKLLAGIFQQGCFISGFTMTIELFSLRNRSNACLADTFSWTXXXXXXXXXXXXXRDWRNYFFWTSITMLPFCLVFYHLPESIRWMMAKDQTKNAQILLKTATLYSNPPLPEKTFENYDKYKRKQESEKLPHYN--------------VLHIFRETLLLRYQLINSFVWFTTAMTYYGVQVKVVEI-GNPFLNFFLSSLVEIPANILCFPIANKYGRKITIGLTNFLVGFS-LFMGYILWKYLDSPWPAIIVFLVGKMLNTGIFNLIFMHVSEFFPTTLRTTAVGMSSSCARIGASFGAMIFQITLYHDSIAFVIVIGCCLLTGVLVFCLPETYRKKMPTSIEE 1736
            E + D W     +Q  +++ +T     N + Y     T  IV +W L C   +   A   +  F     G  +S  +ADR+GRK + +   + + L   AQ         + F LL  +   G +   F + +E+   R R  + +   + +     +L + ++   DWR      S+  L     F+ +PES+RW++A+++ + A ++++ A   +   +  +   ++ + +   E+ +                   V  + R  +L+    I   +W   A+ YYG+ +    + GN +LNF L  LVEIP   L +    ++GR++ +  +  L   + +  G++    L + W  + +FLVGK+  T  F +I+   +E  PT +R+  VG+ S+ AR GA     +  +  Y+D +  ++     L+ G+L   LPET+ +K+P ++EE
Sbjct:  109 ESSSDPWSAWPLDQCFAENFTTETERCNQFVYGSSERT--IVQQWGLQCPENLWKLAFVGTIHFAGLVVGTALSGYLADRYGRKHIFLFCIVFMALTGVAQALSWDYISFLFFALLNAVGTSGVYPLAFIIGVEMVGPRKREMSSIVLNYFYAVGEALLGLSVFLP-DWRQLQLALSVPPLICVAYFWLVPESVRWLLARNRREQAGVIIRRAAKVNRRDISVELMASFKQQELDAETGQEDDVEGGLHVKKDDKIWLAVKEVARSHILMGRYAILLLIWAVNAIVYYGLSLNATSLSGNKYLNFALVCLVEIPGYSLAWLFLRRFGRRVALSGSLLLCSITCVASGFVT---LGANWLVVTLFLVGKLGITSSFAVIYTFTAEMMPTVIRSGGVGVMSTFARFGAMLAPFVPLLASYYDPLPLLLFGTLSLVAGLLSLLLPETFNRKLPDTVEE 557

[Close]

BLAST of slc22a-3 vs. Ensembl Zebrafish
Match: slc22a7a (solute carrier family 22 member 7a [Source:ZFIN;Acc:ZDB-GENE-050506-52])

HSP 1 Score: 184.496 bits (467), Expect = 1.927e-50
Identity = 142/544 (26.10%), Postives = 253/544 (46.51%), Query Frame = 3

Query:  237 EKCLDELGGKNIWILKWFLLISFMKSLPCV-----FSMYSFQFTGVKPDSFHCALP--------PNVSRESM-------IPKERTGDKWEFSSCNQFQ---------------SQDNSTIIPCQNGYNYTMKYFTSSIVTEWDLVCDRAILNALATSSFFVMSFFGAIISCSIADRFGRKVVLITAFMCLNLCEFAQTYITSIYVLIVFKLLAGIFQQGCFISGFTMTIELFSLRNRSNACLADTFSWTXXXXXXXXXXXXXRDWRNYFFWTSITMLPFCLVFYHLPESIRWMMAKDQTKNAQ-ILLKTATLYSNPPLPEK-TFENYDKYKRKQESEKLPHYNVLHIFRETLLLRYQLINSFVWFTTAMTYYGVQVKVVEIG-NPFLNFFLSSLVEIPANILCFPIANKYGRKITIGLTNFLVGFSLFMGYILWKYLDSPWPAIIVFLVGKMLNTGIFNLIFMHVSEFFPTTLRTTAVGMSSSCARIGASFGAMIFQITLYHDSIAF---VIVIGCCLLTGVLVFCLPETYRKKMPTSIEEIKQ 1745
            E  L E+GG N    K+  L+ ++  LP V     F +++F  +GV P   HCALP            +E +       IP+   G    +SSC  +                   ++  +PCQNG+ Y    FTS+  TEWDLVCD   LN    + FF+    GA++   ++D+FGRK ++  +F+   +    + + +S  +  + + L G    G  I+   + +E   +++R+      +  W+  + +L +  Y IRDWR+     +   L   + ++ +PES RW++A  + + AQ  L+  A +       +K   EN  K    ++S K  +++ L + R   L +  L +   WF  A TYYG+   +   G N +L  F+  ++E+PA +  +   ++ GR+     +  + G  + +  ++     +    I V  +GK  +   F + F++ SE +PT LR   +G +S  ARIG S   M+    L+ D   +   V+     + +G +VF LPET   ++P +I ++++
Sbjct:    4 EDVLREIGGFN----KFQFLVLYILWLPRVILPLHFLLHNF-ISGVPPH--HCALPRLDGRFSASGAEKEELAQIVALGIPRNSDGS---YSSCKMYTMPMDFDLNGDLSVLYGNRSNVSVPCQNGWVYDRSQFTSTTATEWDLVCDNKKLNQALATFFFIGVTMGAVVFGQLSDKFGRKPMIQVSFVSSAVFGIIEAFSSSYVMFAIARTLCGFALTGMSITTVALCVEWTDVKHRTFTGTIISLGWSVGNMLLALLAYLIRDWRHLILVVTSPCLVGIIAWWWIPESARWLLANGRVEEAQKYLINCAKMNGKYSYTKKLDIENLKKITIAEDSNK--NHSYLDLVRTPKLRKIVLCSGIFWFAVAFTYYGISFNITGFGLNIYLTQFIYGVIEVPAKVGTYLTLDRIGRRNGQAWSLIIAGALIGLNSVIPTEFAAVRTGIAV--IGKGFSEAAFTIAFLYTSELYPTVLRQCGLGYTSFIARIGGSLAPMVI---LFEDIWHYGPPVVFSATAVFSGCVVFLLPETTNVQLPENILDVEE 530

[Close]

BLAST of slc22a-3 vs. Ensembl Zebrafish
Match: slc22a7b.1 (solute carrier family 22 member 7b, tandem duplicate 1 [Source:ZFIN;Acc:ZDB-GENE-040426-1311])

HSP 1 Score: 179.874 bits (455), Expect = 7.836e-49
Identity = 141/541 (26.06%), Postives = 246/541 (45.47%), Query Frame = 3

Query:  228 MDPEKCLDELGG--KNIWILKWFLLISFMKSLPCVFSMYSFQFTGVKPDSFHCALPP--------NVSRESM----IPKERTGDKWEFSSCN-----QFQSQDNST------IIPCQNGYNYTMKYFTSSIVTEWDLVCDRAILNALATSSFFVMSFFGAIISCSIADRFGRKVVLITAFMCLNLCEFAQTYITSIYVLIVFKLLAGIFQQGCFISGFTMTIELFSLRNRSNACLADTFSWTXXXXXXXXXXXXXRDWRNYFFWTSITMLPFCLVFYHLPESIRWMMAKDQTKNAQILLKTATLYSN-----PPLPEKTFENYDKYKRKQESEKLPHYNVLHIFRETLLLRYQLINSFVWFTTAMTYYGVQVKVVEIG-NPFLNFFLSSLVEIPANILCFPIANKYGRKI----TIGLTNFLVGFSLFMGYILWKYLDSPWPAIIVFLVGKMLNTGIFNLIFMHVSEFFPTTLRTTAVGMSSSCARIGASFGAMIFQITLYHDSIAFVIVIGCCLLTGVLVFCLPETYRKKMPTSIEEIKQ 1745
            M  E  L E+GG  K  + L   L+I  + +LPC F + +F      P S HC +          N+++E      +P +  G     +SC+     QFQ   NS+      ++ CQNG+ +    F S++ TE+DLVCDR  LN    + FF     GA I   + DRFGRK +L+ A++       A  +  S  V  + +   G+   G  I    + IE   + +R+ A +  +  W+ S  IL    Y + DWR      +  +    + +  LPES RW++A  + + A   L      +N       +  +T  N     R   +     Y+ L + R + + +  ++    WF  A TYYG+   +   G N +L  F+   +E+P+ ++ +   +K GR+     T+  T   +G ++ +  +LW       P  ++ ++GK  +   F  +F++ +E +PT LR   +G SS   R+G S   ++  +      +  V+     ++ G+L   LPET+  ++P +IE+I++
Sbjct:    1 MKFENLLAEVGGFGKYQFCLMALLVIPRV-TLPCHFLLNNF--IAAIP-SHHCDISSLSADGIFGNLTQEERLTVGVPAQEDGTP---ASCHMFSHPQFQLLINSSSSSDLPVVECQNGWRFDNSTFKSTLATEFDLVCDRRGLNKATATIFFAGVMIGAAIFGWLTDRFGRKRMLMLAYLISITFGVASAFAQSFIVFAIMRFFTGMGLTGISIISIVLCIEWADIAHRTIAGVMISLDWSLSCMILSGVAYLVNDWRALILTVTAPIALAMITWRWLPESARWLIANGKLEEAHFYLSKCASVNNRQHNLRDIKPETLANVIIADRGDRT-----YSYLDLVRSSKMRKLAMLTGITWFGVAFTYYGISFNISGFGLNLYLTQFIYGAIELPSKLVAYVCLDKLGRRYSQVGTMITTGVCIGITVLIPRVLWV------PCTVIAVLGKGFSEASFTCVFLYTTELYPTVLRQNGLGYSSFIGRVGVSLAPLVSLLDEVWLPLPQVLFCSVAIVAGLLALLLPETHNVRLPETIEDIEK 523

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BLAST of slc22a-3 vs. Ensembl Zebrafish
Match: slc22a7b.3 (solute carrier family 22 member 7b, tandem duplicate 3 [Source:ZFIN;Acc:ZDB-GENE-131120-103])

HSP 1 Score: 176.407 bits (446), Expect = 1.335e-47
Identity = 138/518 (26.64%), Postives = 236/518 (45.56%), Query Frame = 3

Query:  282 KWFLLISFMKS--LPCVFSMYSFQFTGVKPDSFHC--------ALPPNVSRESM----IPKERTGDKWEFSSCN-----QFQSQDNST------IIPCQNGYNYTMKYFTSSIVTEWDLVCDRAILNALATSSFFVMSFFGAIISCSIADRFGRKVVLITAFMCLNLCEFAQTYITSIYVLIVFKLLAGIFQQGCFISGFTMTIELFSLRNRSNACLADTFSWTXXXXXXXXXXXXXRDWRNYFFWTSITM---LPFC-LVFYHLPESIRWMMAKDQTKNAQILL-KTATLYSNPPLPEKTFENYDKYKRKQESEKLPHYNVLHIFRETLLLRYQLINSFVWFTTAMTYYGVQVKVVEIG-NPFLNFFLSSLVEIPANILCFPIANKYGRKITIGLTNFLVGFSLFMGYILWKYLDSPWPAIIVFLVGKMLNTGIFNLIFMHVSEFFPTTLRTTAVGMSSSCARIGASFGAMIFQITLYHDSIAFVIVIGCCLLTGVLVFCLPETYRKKMPTSIEEIK 1742
            K  L ISF+    +PC F + +F      P S HC         L  N++ E      +P +  G      SC+     QFQ   NS+      ++ CQNG+++    F S++ T+WDLVCD   LN    + FFV   FGA     ++DRFGRK +L+ +++       A  + TS  +  V +  +G    G  I    + +E   + +R    + D+ +W   S  L +  YFIRDWR    W ++ +   L  C ++++ +PES RW++A    + A   L K A +     +  +            + +K   Y  L + R   + +  ++   VWF  A   YG+ + +   G N +L  F+   +E+P+ ++ + +  K GR+ T        G SL +   + K  D      +V ++GK      F  I ++ SE +PT LR   +G +S  AR+G S   ++  +  +    +  I+    L+  V+ + LPET  + +P +IE+++
Sbjct:   18 KMILCISFVGRFIIPCHFLLSNF--IAAIP-SHHCDISFLDADGLFGNLTEEERLIVSVPTQEDGSP---VSCHMFSHPQFQLLINSSSSSDLPVVECQNGWHFDNSTFISTLATQWDLVCDNRGLNKAVATIFFVGVMFGAAFFGGMSDRFGRKPMLLVSYISGMAFALASVFSTSFTMFAVLRFFSGFTITGIVIVSSVLNLEWVDIEHRRLVSIIDSMAWAVGSTSLALIAYFIRDWR----WLTVAVTSPLVLCTILWWWVPESARWLIANGDVEKAHYYLHKCAVMNRKAEVTSRIKPEALAISVSDQGKK--KYTYLDLVRTPKMRKLAMLTGTVWFCVATMTYGISLNITGFGLNMYLTQFVYGAIEVPSKLIVYYLLEKIGRRKTEAGAQLFAGISLMINIFIPK--DQWIGRTVVAVLGKGFAVAAFCTIVLYSSELYPTVLRQNGMGYNSFLARLGVSVAPLVLLLDTFWGQFSQTILCSVALIASVVAWNLPETRDRCLPETIEDVE 521

[Close]

BLAST of slc22a-3 vs. Ensembl Zebrafish
Match: slc22a7b.3 (solute carrier family 22 member 7b, tandem duplicate 3 [Source:ZFIN;Acc:ZDB-GENE-131120-103])

HSP 1 Score: 176.407 bits (446), Expect = 1.810e-47
Identity = 139/517 (26.89%), Postives = 235/517 (45.45%), Query Frame = 3

Query:  282 KWFLLISFMKS--LPCVFSMYSFQFTGVKPDSFHC--------ALPPNVSRESM----IPKERTGDKWEFSSCN-----QFQSQDNST------IIPCQNGYNYTMKYFTSSIVTEWDLVCDRAILNALATSSFFVMSFFGAIISCSIADRFGRKVVLITAFMCLNLCEFAQTYITSIYVLIVFKLLAGIFQQGCFISGFTMTIELFSLRNRSNACLADTFSWTXXXXXXXXXXXXXRDWRNYFFWTSITM---LPFC-LVFYHLPESIRWMMAKDQTKNAQILL-KTATLYSNPPLPEKTFENYDKYKRKQESEKLPHYNVLHIFRETLLLRYQLINSFVWFTTAMTYYGVQVKVVEIG-NPFLNFFLSSLVEIPANILCFPIANKYGRKITIGLTNFLVGFSLFMGYILWKYLDSPWPAIIVFLVGKMLNTGIFNLIFMHVSEFFPTTLRTTAVGMSSSCARIGASFGAMIFQITLYHDSIAFVIVIGCCLLTGVLVFCLPETYRKKMPTSIEEI 1739
            K  L ISF+    +PC F + +F      P S HC         L  N++ E      +P +  G      SC+     QFQ   NS+      ++ CQNG+++    F S++ T+WDLVCD   LN    + FFV   FGA     ++DRFGRK +L+ +++       A  + TS  +  V +  +G    G  I    + +E   + +R    + D+ +W   S  L +  YFIRDWR    W ++ +   L  C ++++ +PES RW++A    + A   L K A +     +  +            + +K   Y  L + R   + +  ++   VWF  A   YG+ + +   G N +L  F+   +E+P+ ++ + +  K GR+ T        G SL +   + K  D      +V ++GK      F  I ++ SE +PT LR   +G +S  AR+G S   ++  +  +    +  I+    L+  V+ + LPET  + +P +IE+I
Sbjct:   18 KMILCISFVGRFIIPCHFLLSNF--IAAIP-SHHCDISFLDADGLFGNLTEEERLIVSVPTQEDGSP---VSCHMFSHPQFQLLINSSSSSDLPVVECQNGWHFDNSTFISTLATQWDLVCDNRGLNKAVATIFFVGVMFGAAFFGGMSDRFGRKPMLLVSYISGMAFALASVFSTSFTMFAVLRFFSGFTITGIVIVSSVLNLEWVDIEHRRLVSIIDSMAWAVGSTSLALIAYFIRDWR----WLTVAVTSPLVLCTILWWWVPESARWLIANGDVEKAHYYLHKCAVMNRKAEVTSRIKPEALAISVSDQGKK--KYTYLDLVRTPKMRKLAMLTGTVWFCVATMTYGISLNITGFGLNMYLTQFVYGAIEVPSKLIVYYLLEKIGRRKTEAGAQLFAGISLMINIFIPK--DQWIGRTVVAVLGKGFAVAAFCTIVLYSSELYPTVLRQNGMGYNSFLARLGVSVAPLVLLLDTFWGQFSQTILCSVALIASVVAWNLPETRDRCLPETIEDI 520

[Close]

BLAST of slc22a-3 vs. Ensembl Zebrafish
Match: BX005258.2 (solute carrier family 22 member 7b, tandem duplicate 3 [Source:NCBI gene;Acc:100001772])

HSP 1 Score: 175.252 bits (443), Expect = 2.926e-47
Identity = 138/516 (26.74%), Postives = 234/516 (45.35%), Query Frame = 3

Query:  282 KWFLLISFMKS--LPCVFSMYSFQFTGVKPDSFHC--------ALPPNVSRESM----IPKERTGDKWEFSSCN-----QFQSQDNST------IIPCQNGYNYTMKYFTSSIVTEWDLVCDRAILNALATSSFFVMSFFGAIISCSIADRFGRKVVLITAFMCLNLCEFAQTYITSIYVLIVFKLLAGIFQQGCFISGFTMTIELFSLRNRSNACLADTFSWTXXXXXXXXXXXXXRDWRNYFFWTSITM---LPFC-LVFYHLPESIRWMMAKDQTKNAQILL-KTATLYSNPPLPEKTFENYDKYKRKQESEKLPHYNVLHIFRETLLLRYQLINSFVWFTTAMTYYGVQVKVVEIG-NPFLNFFLSSLVEIPANILCFPIANKYGRKITIGLTNFLVGFSLFMGYILWKYLDSPWPAIIVFLVGKMLNTGIFNLIFMHVSEFFPTTLRTTAVGMSSSCARIGASFGAMIFQITLYHDSIAFVIVIGCCLLTGVLVFCLPETYRKKMPTSIEE 1736
            K  L ISF+    +PC F + +F      P S HC         L  N++ E      +P +  G      SC+     QFQ   NS+      ++ CQNG+++    F S++ T+WDLVCD   LN    + FFV   FGA     ++DRFGRK +L+ +++       A  + TS  +  V +  +G    G  I    + +E   + +R    + D+ +W   S  L +  YFIRDWR    W ++ +   L  C ++++ +PES RW++A    + A   L K A +     +  +            + +K   Y  L + R   + +  ++   VWF  A   YG+ + +   G N +L  F+   +E+P+ ++ + +  K GR+ T        G SL +   + K  D      +V ++GK      F  I ++ SE +PT LR   +G +S  AR+G S   ++  +  +    +  I+    L+  V+ + LPET  + +P +IE+
Sbjct:   18 KMILCISFVGRFIIPCHFLLSNF--IAAIP-SHHCDISFLDADGLFGNLTEEERLIVSVPTQEDGSP---VSCHMFSHPQFQLLINSSSSSDLPVVECQNGWHFDNSTFISTLATQWDLVCDNRGLNKAVATIFFVGVMFGAAFFGGMSDRFGRKPMLLVSYISGMAFALASVFSTSFTMFAVLRFFSGFTITGIVIVSSVLNLEWVDIEHRRLVSIIDSMAWAVGSTSLALIAYFIRDWR----WLTVAVTSPLVLCTILWWWVPESARWLIANGDVEKAHYYLHKCAVMNRKAEVTSRIKPEALAISVSDQGKK--KYTYLDLVRTPKMRKLAMLTGTVWFCVATMTYGISLNITSFGLNMYLTQFVYGAIEVPSKLIVYYLLEKIGRRKTEAGAQLFAGISLMINIFIPK--DQWIGRTVVAVLGKGFAVAAFCTIVLYSSELYPTVLRQNGMGYNSFLARLGVSVAPLVLLLDTFWGQFSQTILCSVALIASVVAWNLPETRDRCLPETIED 519

[Close]

BLAST of slc22a-3 vs. Ensembl Xenopus
Match: slc22a4 (solute carrier family 22 (organic cation/zwitterion transporter), member 4 [Source:NCBI gene;Acc:394948])

HSP 1 Score: 181.415 bits (459), Expect = 2.134e-49
Identity = 125/465 (26.88%), Postives = 236/465 (50.75%), Query Frame = 3

Query:  375 HCALPPNVSRESMIPKERTGDKWEFSSCNQFQSQD-NSTII---PCQNGYNYTMKYFTSSIVTEWDLVCDRAILNALATSSFFVMSFFGAIISCSIADRFGRKVVLITAFMCLNLCEFAQTYITSIYVLIVFKLLAGIFQQGCFISGFTMTIELFSLRNRSN-ACLADTFSWTXXXXXXXXXXXXXRDWRNYFFWTSITMLPFCL-VFYHLPESIRWMMAKDQTKNAQILLKTATLYSNPPLPE---KTFENYDKYKRKQESEKLPHYNVLHIFRETLLLRYQLINSFVWFTTAMTYYGVQVKVVEI-GNPFLNFFLSSLVEIPANILCFPIANKYGRKITIGLTNFLVGFSLFMGYILWKYLDSPWPAIIVFLVGKMLNTGIFNLIFMHVSEFFPTTLRTTAVGMSSSCARIGASFGAMIFQITLYHDSIAFVIVIGCCLLTGVLVFCLPETYRKKMPTSIEEI 1739
            + ++P    ++S   + R G    +S+      +D + T I   PC +G+NY+   + S+IVTEWD+VC+      L TS FFV    G+ +S  ++D FGRK +L             Q + TS  +  +F L+ G+ Q   +++ F +  E+     R   + L     +     +L ++ YFIRDWR      +I  L FC+ +++ +PES +W++ K + + A+++++ A   +  P P    KT E  D  +R++ S     Y +L + +   +    ++  F+W  T++ Y+G+ +    + G+PFLN FL + +E+P+NI  + +     R+ +  +   L+   + +  I    LD    + ++ +VGK   T  F++++++ +E +PT +R T VG+ S  +RIG+        +  Y   + F+++    +L G+   CLPE++   +P +IEE+
Sbjct:   64 NASIPRQDGQDSQCRRYRLGTLTNYSALGLLPGRDVDVTGIEQEPCLDGWNYSKSLYLSTIVTEWDIVCENDWKGPLTTSLFFVGVLLGSFVSGQLSDSFGRKKILFVTMAIQTGFSIVQVFSTSWEMFAIFFLIVGMGQISNYVAAFILGTEILGKSARIIFSTLGTCIFFAIGYMMLPLFAYFIRDWRTLLLALTIPGL-FCIPLWWIIPESPQWLICKGRIEEAEVIIRKAAKINRVPAPAVIFKTTELEDLAERQKRS-----YTLLDLVKTFNVRIITIMTVFLWLITSIGYFGISLNTPNLHGDPFLNCFLLAAIEVPSNIFAWLLLRYISRRYS--MCGSLLLGGVVLLLIQLVPLDLQILSTVLVMVGKFGVTAAFSMVYVYTAELYPTVIRNTGVGIGSVSSRIGSVISPYFVYLGAYDRFLPFILMGSLTVLIGMFTLCLPESHGMPLPDTIEEM 520

[Close]

BLAST of slc22a-3 vs. Ensembl Xenopus
Match: slc22a4 (solute carrier family 22 (organic cation/zwitterion transporter), member 4 [Source:NCBI gene;Acc:394948])

HSP 1 Score: 181.8 bits (460), Expect = 2.328e-49
Identity = 122/465 (26.24%), Postives = 238/465 (51.18%), Query Frame = 3

Query:  375 HCALPPNVSRESMIPKERTGDKWEFSSCNQFQSQD-NSTII---PCQNGYNYTMKYFTSSIVTEWDLVCDRAILNALATSSFFVMSFFGAIISCSIADRFGRKVVLITAFMCLNLCEFAQTYITSIYVLIVFKLLAGIFQQGCFISGFTMTIELFSLRNRSN-ACLADTFSWTXXXXXXXXXXXXXRDWRNYFFWTSITMLPFCL-VFYHLPESIRWMMAKDQTKNAQILLKTATLYSNPPLPE---KTFENYDKYKRKQESEKLPHYNVLHIFRETLLLRYQLINSFVWFTTAMTYYGVQVKVVEI-GNPFLNFFLSSLVEIPANILCFPIANKYGRKITIGLTNFLVGFSLFMGYILWKYLDSPWPAIIVFLVGKMLNTGIFNLIFMHVSEFFPTTLRTTAVGMSSSCARIGASFGAMIFQITLYHDSIAFVIVIGCCLLTGVLVFCLPETYRKKMPTSIEEI 1739
            + ++P    ++S   + R G    +S+      +D + T I   PC +G+NY+   + S+IVTEWD+VC+      L TS FFV    G+ +S  ++D FGRK +L             Q + TS  +  +F L+ G+ Q   +++ F +  E+     R   + L     +     +L ++ YFIRDWR      +I  L FC+ +++ +PES +W++ K + + A+++++ A   +  P P    KT E  D  +R++ S     Y +L + +   +    ++  F+W   ++ Y+G+ +    + G+P++N FLS+++E+PA ++ + +   + R+ +   T  L G  L    ++ + L     +I++ ++GK   T  F++++++ +E +PT +R   VG SS  +R+G+        +  Y   + F+++    +L G+   CLPE++   +P +IEE+
Sbjct:   64 NASIPRQDGQDSQCRRYRLGTLTNYSALGLLPGRDVDVTGIEQEPCLDGWNYSKSLYLSTIVTEWDIVCENDWKGPLTTSLFFVGVLLGSFVSGQLSDSFGRKKILFVTMAIQTGFSIVQVFSTSWEMFAIFFLIVGMGQISNYVAAFILGTEILGKSARIIFSTLGTCIFFAIGYMMLPLFAYFIRDWRTLLLALTIPGL-FCIPLWWIIPESPQWLICKGRIEEAEVIIRKAAKINRVPAPAVIFKTTELEDLAERQKRS-----YTLLDLVKTFNVRIITIMTVFLWMIISVGYFGLSLNTPNLHGDPYVNCFLSAIIEVPAYVIAWLLLRSFPRRYSTASTLVLGGVVLLFIQLVPQELGI--LSIVLVMLGKFGITSAFSMVYVYTAELYPTVVRNMGVGASSMASRMGSILSPYFVYLGAYDRFLPFILMGSLTVLIGMFTLCLPESHGMPLPDTIEEM 520

[Close]

BLAST of slc22a-3 vs. Ensembl Xenopus
Match: ccdc30 (coiled-coil domain containing 30 [Source:Xenbase;Acc:XB-GENE-1004904])

HSP 1 Score: 180.259 bits (456), Expect = 1.163e-48
Identity = 144/503 (28.63%), Postives = 234/503 (46.52%), Query Frame = 3

Query:  315 LPCVFSMYSFQFTGVKPDSFHCALPPNVS-------------RESMIPKERTGDKWEFSSCNQFQSQD----------NSTIIPCQNGYNYTMKYFTSSIVTEWDLVCDRAILNALATSSFFVMSFFGAIISCSIADRFGRKVVLITAFMCLNLCEFAQTYITSIYVLIVFKLLAGIFQQGCFISGFTMTIELFSLRNRSNACLADTFSWTXXXXXXXXXXXXXRDWRNYFFWTSITMLPFCLVFYHLPESIRWMMAKDQTKNAQILLKTATLYSNPPLPEKTFENYD-KYKRKQESEKLPHYNVLHIFRETLLLRYQLINSFVWFTTAMTYYGVQVKVVEI-GNPFLNFFLSSLVEIPANIL-CFPIANKYGRKITIGLTNFLVGFSLFMGYILWKYLDSPWPAIIVFLVGKMLNTGIFNLIFMHVSEFFPTTLRTTAVGMSSSCARIGASFGAMIFQITLYHDSIAFVIVIGCCLLTGVLVFCLPETYRKKMPTSIEEIKQ 1745
            L  VF   + +F    P++    L PN S             ++ ++ K+  GD WE + C++F+ ++          N T+  C NGY Y      SSIVT+W LVC+R  L  L   +F      GA+I   IADR GR+++L        L   A  +    Y  ++ + L  +   G ++  F    E   ++ RS A +     +     I+ +  + +R W  Y    S+T LPF L  + LPE+  W+ ++ + K  + L+ T   ++    P K  E    +  +K E + L  ++VL +F      R  +    +WFT ++ YY   +  V + GN +LN FL+S VEIP+ I+ CF + +K GR+ T  L  FL+  ++  G I+    D     I + + GK      F LI+++ +E +PT +R+ AVG  S   RIG+        +T     +  ++V     LTGVL   LPET    + ++IEE  +
Sbjct:   33 LASVFIAITPKFICRAPENISSVLLPNASTLRLEDVWELWTPKDYLVVKQENGDIWELNQCSRFKRENTSYLTYSYDGNKTLFSCSNGYYYDNTNLESSIVTDWHLVCEREWLAKLIQPTFMFGVLIGAVIFGDIADRVGRRLILWLTSTGQFLFGIAVAFTFDYYSFVIVRFLLAMVSSGYYVVVFVYVTEYVGIKARSWASMHVHAFFAVGVMIVSLVGFLVRTWWMYQIILSLTTLPFVLCCWMLPETPFWLYSQGKHKEVEKLIGTIEKWNKISTPCKLSELCSVQETQKTEMDTLKKHSVLDLFYNWSFARRTVTVWLIWFTGSLGYYVFALNSVNLGGNEYLNLFLTSAVEIPSYIVACFGM-DKIGRRNT--LAPFLILSAVICGIIMLIPQDHSTVTIAMSMGGKFSIAVAFGLIYLYTAELYPTIVRSLAVGSGSMMCRIGSVVAPFCVYLTDVWIFMPQMLVGIMAFLTGVLTLKLPETLGVPLTSTIEEAAE 532

[Close]

BLAST of slc22a-3 vs. Ensembl Xenopus
Match: slc22a4 (solute carrier family 22 (organic cation/zwitterion transporter), member 4 [Source:NCBI gene;Acc:394948])

HSP 1 Score: 179.104 bits (453), Expect = 2.228e-48
Identity = 124/467 (26.55%), Postives = 237/467 (50.75%), Query Frame = 3

Query:  375 HCALPPNVSRESMIPKERTGDKWEFSSCNQFQSQD-NSTII---PCQNGYNYTMKYFTSSIVTEWDLVCDRAILNALATSSFFVMSFFGAIISCSIADRFGRKVVLITAFMCLNLCEFAQTYITSIYVLIVFKLLAGIFQQGCFISGFTMTIELFSLRNRSN-ACLADTFSWTXXXXXXXXXXXXXRDWRNYFFWTSITMLPFCL-VFYHLPESIRWMMAKDQTKNAQILLKTATLYSNPPLPE---KTFENYDKYKRKQESEKLPHYNVLHIFRETLLLRYQLINSFVWFTTAMTYYGVQVKVVEI-GNPFLNFFLSSLVEIPANILCFPIANKYGRKITIGLTNFLVGFSLFMGYILWKYLDSPWPAIIVFLVGKMLNTGIFNLIFMHVSEFFPTTLRTTAVGMSSSCARIGASFGAMIFQITLYHDSIAFVIVIGCCLLTGVLVFCLPETYRKKMPTSIEEIKQ 1745
            + ++P    ++S   + R G    +S+      +D + T I   PC +G+NY+   + S+IVTEWD+VC+      L TS FFV    G+ +S  ++D FGRK +L             Q + TS  +  +F L+ G+ Q   +++ F +  E+     R   + L     +     +L ++ YFIRDWR      +I  L FC+ +++ +PES +W++ K + + A+++++ A   +  P P    KT E  D  +R++ S     Y +L + +   +    ++  F+W  T++ Y+G+ +    + G+PFLN FL + +E+P+NI  + +     R+ +  +   L+   + +  I    LD    + ++ +VGK   T  F++++++ +E +PT +R T VG+ S  +RIG+        +  Y+  + ++++    +  G+LV   PET+ K +P +IE+ + 
Sbjct:   65 NASIPRQDGQDSQCRRYRLGTLTNYSALGLLPGRDVDVTGIEQEPCLDGWNYSKSLYLSTIVTEWDIVCENDWKGPLTTSLFFVGVLLGSFVSGQLSDSFGRKKILFVTMAIQTGFSIVQVFSTSWEMFAIFFLIVGMGQISNYVAAFILGTEILGKSARIIFSTLGTCIFFAIGYMMLPLFAYFIRDWRTLLLALTIPGL-FCIPLWWIIPESPQWLICKGRIEEAEVIIRKAAKINRVPAPAVIFKTTELEDLAERQKRS-----YTLLDLVKTFNVRIITIMTVFLWLITSIGYFGISLNTPNLHGDPFLNCFLLAAIEVPSNIFAWLLLRYISRRYS--MCGSLLLGGVVLLLIQLVPLDLQILSTVLVMVGKFGVTAAFSMVYVYTAELYPTVIRNTGVGIGSVSSRIGSVISPYFVYLGAYNRLLPYILMGSLTVANGILVLFFPETFGKPLPETIEQTQN 523

[Close]

BLAST of slc22a-3 vs. Ensembl Xenopus
Match: emc2 (ER membrane protein complex subunit 2 [Source:Xenbase;Acc:XB-GENE-484487])

HSP 1 Score: 171.785 bits (434), Expect = 9.922e-46
Identity = 121/466 (25.97%), Postives = 235/466 (50.43%), Query Frame = 3

Query:  375 HCALPPNVSRESMIPKERTGDKWEFSSCNQFQSQD-NSTII---PCQNGYNYTMKYFTSSIVTEWDLVCDRAILNALATSSFFVMSFFGAIISCSIADRFGRKVVLITAFMCLNLCEFAQTYITSIYVLIVFKLLAGIFQQGCFISGFTMTIELFSLRNRSN-ACLADTFSWTXXXXXXXXXXXXXRDWRNYFFWTSITMLPFCL-VFYHLPESIRWMMAKDQTKNAQILLKTATLYSNPPLPEKTFENYDKYKRKQESEKLPHYNVLHIFRETLLLRYQLINSF----VWFTTAMTYYGVQVKVVEI-GNPFLNFFLSSLVEIPANILCFPIANKYGRKITIGLTNFLVGFSLFMGYILWKYLDSPWPAIIVFLVGKMLNTGIFNLIFMHVSEFFPTTLRTTAVGMSSSCARIGASFGAMIFQITLYHDSIAFVIVIGCCLLTGVLVFCLPETYRKKMPTSIEEI 1739
            + ++P    ++S   + R G    +S+      +D + T I   PC +G+NY+   + S+IVTEW+LVC+      L TS FFV    G+ +S  ++DRFGRK VL             Q +  +  +     ++ G+ Q   +++ F +  E+     R   + L     +     +L ++ YFIRDWR      +I  L FC+ +++ +PES RW++++ + + A+ +++ A   +    P+  F     +   QE ++L H +  H F + L  R   I +F    +W   ++ Y+G+ +    + G+P++N FLS+++E+PA ++ + +   + R+ +   T  L G  L    ++ + L     +I++ ++GK   T  F++++++ +E +PT +R   VG SS  +R+G+        +  Y   + F+++    +L G+   CLPE++   +P +IEE+
Sbjct:   64 NASIPRQDGQDSQCRRYRLGTLTNYSALGLLPGRDVDVTGIEQEPCLDGWNYSKSLYLSTIVTEWNLVCENDWKGPLTTSLFFVGVLIGSFVSGQMSDRFGRKKVLFATMAVQTGFSIIQVFSVNWEMFTALFIIVGMGQISNYVAAFILGAEILDKSVRIIFSTLGVCIFYAIGYMLLPLFAYFIRDWRTLLLALTIPGL-FCIPLWWIIPESPRWLISQGRFQEAEDIIRKAAKKNGITPPDSIF----NFTELQEQKELTHKS--HTFLDLLKTRNIRIITFLSILLWMIISVGYFGLSLNTPNLHGDPYVNCFLSAIIEVPAYVIAWLLLRSFPRRYSTASTLVLGGVVLLFIQLVPQELGI--LSIVLVMLGKFGITSAFSMVYVYTAELYPTVVRNMGVGASSMASRMGSILSPYFVYLGAYDRFLPFILMGSLTVLIGMFTLCLPESHGMPLPDTIEEM 520

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BLAST of slc22a-3 vs. Ensembl Mouse
Match: Slc22a7 (solute carrier family 22 (organic anion transporter), member 7 [Source:MGI Symbol;Acc:MGI:1859559])

HSP 1 Score: 177.178 bits (448), Expect = 7.111e-48
Identity = 135/537 (25.14%), Postives = 244/537 (45.44%), Query Frame = 3

Query:  228 MDPEKCLDELGGKNIWILKWFLLISFMK-SLPCVFSMYSFQFTGVKPDSFHCALP---PNVSRESM-----IPKERTGDKWEFSSCNQF---QSQDNSTI----------------IPCQNGYNYTMKYFTSSIVTEWDLVCDRAILNALATSSFFVMSFFGAIISCSIADRFGRKVVLITAFMCLNLCEFAQTYITSIYVLIVFKLLAGIFQQGCFISGFTMTIELFSLRNRSNACLADTFSWTXXXXXXXXXXXXXRDWRNYFFWTSITMLPFCLVFYHLPESIRWMMAKDQTKNAQILLKTATLYSNPPLPEKTF--ENYDKYKRKQESEKLPHYNVLHIFRETLLLRYQLINSFVWFTTAMTYYGVQVKVVEIG-NPFLNFFLSSLVEIPANILCFPIANKYGRKITIGLTNFLVGFSLFMGYILWKYLDSPWPAIIVFLVGKMLNTGIFNLIFMHVSEFFPTTLRTTAVGMSSSCARIGASFGAMIFQITLYHDSIAFVIVIGCCLLTGVLVFCLPETYRKKMPTSIEEIKQ 1745
            M  E+ L ++GG   + L+  +L++  +  LP  F +  F        + HCALP    N+S + +     +P+E  G    FSSC +F   Q+  N T+                +PC  G+ Y    F+S+I TEWDLVC +  LN + ++ FF+    GA++   ++DRFGR+ +L+ A++             +  + +  ++L G    G  I    + +E   + +R+ A +  T  WT    +L +  Y IR WR      ++  +P  +  + +PES RW++ + + + A+  L      +  P+ E +   E  +K    +   + P Y  L +FR + L    L    +WF    +YYG+ +    +G   +    L   VE+P+ I  F +    GR++T      L+  +L  G  L    D+      + ++GK  +   F   ++  SE +PT LR T +G ++   R+GAS   ++  +      +  +   G   L    V  LPET + ++P +I+++++
Sbjct:    1 MGFEELLHKVGGFGPFQLRNLVLLALPRFLLPMHFLLPIFM---AAVPAHHCALPDAPANLSHQDLWLKTHLPRETDGS---FSSCLRFAYPQALPNVTLGTEVYNSGEPEGEPLTVPCSQGWEYDRSEFSSTIATEWDLVCQQRGLNKVTSTCFFIGVLLGAVVYGYLSDRFGRRRLLLVAYVSTLALGLMSAASVNYIMFVTTRMLTGSALAGFTIIVLPLELEWLDVEHRTVAGVISTTFWTGGVLLLTLVGYLIRSWRWLLLAATLPCVPGIISIWWVPESARWLLTQGRVEEAKKYLSICAKLNGRPISEDSLSQEALNKVITMERVSQRPSY--LDLFRTSQLRHVSLCCMMMWFGVNFSYYGLTLDASGLGLTVYQTQLLFGAVEVPSKITVFFLVRLVGRRLTEA--GMLLATALTFGISLLVSSDTKSWITALVVIGKAFSEAAFTTAYLFTSELYPTVLRQTGMGFTALIGRLGASLAPLVVLLDGVWLLLPKLAYGGISFLAACTVLLLPETKKAQLPETIQDVER 527

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BLAST of slc22a-3 vs. Ensembl Mouse
Match: Slc22a8 (solute carrier family 22 (organic anion transporter), member 8 [Source:MGI Symbol;Acc:MGI:1336187])

HSP 1 Score: 162.54 bits (410), Expect = 1.227e-42
Identity = 138/479 (28.81%), Postives = 215/479 (44.89%), Query Frame = 3

Query:  348 FTGVKPDSFHCALPPNVSRES-MIPKERTGDKWEFSSCNQFQSQDNSTII--------PCQNGYNYTMKYFTSSIVTEWDLVCDRAILNALATSSFFVMSFFGAIISCSIADRFGRKVVLITAFMCLNLCEFAQTYITSIYVLIVFKLLAGIFQQGCFISGFTMTIELFSLRNRSNACLADTFSWTXXXXXXXXXXXXXRDWRNYFFWTSITMLPFCLVFYHLPESIRWMMAKDQ-TKNAQILLKTATLYSNPPLPEK-TFENYDKYKRKQESEKLPHYNVLHIFRETLLLRYQLINSFVWFTTAMTYYGVQVKVVEIG-NPFLNFFLSSLVEIPANILCFPIANKYGRKITIGLTNFLVGFSLFMGYILWKYLDSPWPAIIVFLVGKMLNTGIFNLIFMHVSEFFPTTLRTTAVGMSSSCARIGASFGAMIFQITLYHDSIAFVIVIGCCLLTGVLVFCLPETYRKKMPTSIEEIKQW 1748
            FT   PD  HC  PPN S E  ++P    G       C +F    N+++         PC +G+ Y     T  IVTEWDLVC    L  +A S F      G  +   ++DRFGRK +L  +++ L     +  +  S+ V ++F+ L G    G  +S   + +E      R+ +     + +T   FIL    Y +  WR      S     F L+ + +PESIRW++   + +K  + L + AT        EK T E      +K  +     Y +  +FR ++L R     S  WF T   YY + + V E G N ++   +   V+IPA  +     +  GR+IT G    L G ++     +   +     A+ VF  GK   +G F+ +F++ SE +PT LR T +G+S+  AR+G+    ++         I  VI     LL G   F L ET  + +P +IE+I+ W
Sbjct:   40 FTATTPDH-HCRPPPNASLEPWVLPLGPNGKP---EKCLRFVHLPNASLPNDTQGATEPCLDGWIYNSTRDT--IVTEWDLVCGSNKLKEMAQSVFMAGILVGGPVFGELSDRFGRKPILTWSYLLLAASGSSAAFSPSLTVYMIFRFLCGCSISGISLSTIILNVEWVPTSTRAISSTTIGYCYTIGQFILPGLAYAVPQWRWLQLSVSAAFFIFSLLSWWVPESIRWLVLSGKFSKALKTLQRVATFNGKKEEGEKLTVEELKFNLQKDITSAKVKYGLSDLFRVSILRRVTFCLSLAWFATGFAYYSLAMGVEEFGVNIYILQIIFGGVDIPAKFITILSISYLGRRITQGFLLILAGVAILALIFVSSEMQLLRTALAVF--GKGCLSGSFSCLFLYTSELYPTVLRQTGMGISNIWARVGSMIAPLVKITGELQPFIPNVIFGTMTLLGGSAAFFLLETLNRPLPETIEDIQDW 510

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Query:  348 FTGVKPDSFHCALPPNVSRES-MIPKERTGDKWEFSSCNQFQSQDNSTII--------PCQNGYNYTMKYFTSSIVTEWDLVCDRAILNALATSSFFVMSFFGAIISCSIADRFGRKVVLITAFMCLNLCEFAQTYITSIYVLIVFKLLAGIFQQGCFISGFTMTIELFSLRNRSNACLADTFSWTXXXXXXXXXXXXXRDWRNYFFWTSITMLPFCLVFYHLPESIRWMMAKDQ-TKNAQILLKTATLYSNPPLPEK-TFENYDKYKRKQESEKLPHYNVLHIFRETLLLRYQLINSFVWFTTAMTYYGVQVKVVEIG-NPFLNFFLSSLVEIPANILCFPIANKYGRKITIGLTNFLVGFSLFMGYILWKYLDSPWPAIIVFLVGKMLNTGIFNLIFMHVSEFFPTTLRTTAVGMSSSCARIGASFGAMIFQITLYHDSIAFVIVIGCCLLTGVLVFCLPETYRKKMPTSIEEIKQW 1748
            FT   PD  HC  PPN S E  ++P    G       C +F    N+++         PC +G+ Y     T  IVTEWDLVC    L  +A S F      G  +   ++DRFGRK +L  +++ L     +  +  S+ V ++F+ L G    G  +S   + +E      R+ +     + +T   FIL    Y +  WR      S     F L+ + +PESIRW++   + +K  + L + AT        EK T E      +K  +     Y +  +FR ++L R     S  WF T   YY + + V E G N ++   +   V+IPA  +     +  GR+IT G    L G ++     +   +     A+ VF  GK   +G F+ +F++ SE +PT LR T +G+S+  AR+G+    ++         I  VI     LL G   F L ET  + +P +IE+I+ W
Sbjct:   40 FTATTPDH-HCRPPPNASLEPWVLPLGPNGKP---EKCLRFVHLPNASLPNDTQGATEPCLDGWIYNSTRDT--IVTEWDLVCGSNKLKEMAQSVFMAGILVGGPVFGELSDRFGRKPILTWSYLLLAASGSSAAFSPSLTVYMIFRFLCGCSISGISLSTIILNVEWVPTSTRAISSTTIGYCYTIGQFILPGLAYAVPQWRWLQLSVSAAFFIFSLLSWWVPESIRWLVLSGKFSKALKTLQRVATFNGKKEEGEKLTVEELKFNLQKDITSAKVKYGLSDLFRVSILRRVTFCLSLAWFATGFAYYSLAMGVEEFGVNIYILQIIFGGVDIPAKFITILSISYLGRRITQGFLLILAGVAILALIFVSSEMQLLRTALAVF--GKGCLSGSFSCLFLYTSELYPTVLRQTGMGISNIWARVGSMIAPLVKITGELQPFIPNVIFGTMTLLGGSAAFFLLETLNRPLPETIEDIQDW 510

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BLAST of slc22a-3 vs. Ensembl Mouse
Match: Slc22a21 (solute carrier family 22 (organic cation transporter), member 21 [Source:MGI Symbol;Acc:MGI:1929481])

HSP 1 Score: 162.155 bits (409), Expect = 1.906e-42
Identity = 107/419 (25.54%), Postives = 212/419 (50.60%), Query Frame = 3

Query:  498 CQNGYNYTMKYFTSSIVTEWDLVCDRAILNALATSSFFVMSFFGAIISCSIADRFGRKVVLITAFMCLNLCEFAQTYITSIYVLIVFKLLAGIFQQGCFISGFTMTIELFSLRNRSN-ACLADTFSWTXXXXXXXXXXXXXRDWRNYFFWTSITMLPFCLVFYHLPESIRWMMAKDQTKNAQILLKTATLYSNPPLPEKTFENYDKYKRKQESEKLPHYNVLHIFRETLLLRYQLINSFV-WFTTAMTYYGVQVKVVEI-GNPFLNFFLSSLVEIPANILCFPIANKYGRKITIGLTNFLVGFSLFMGYILWKYLDSPWPAIIVFLVGKMLNTGIFNLIFMHVSEFFPTTLRTTAVGMSSSCARIGASFGAMIFQITLYHDSIAFVIVIGCCLLTGVLVFCLPETYRKKMPTSIEEIKQ 1745
            C +G+ Y    F S+IVTEWDLVC       L TS F+V    G+ IS  ++DRFGRK +L           F Q +  +  +  +   L G+     +++ F +  E+ S   R   A L     + F   +L ++ YFIR+WR      ++  +    +++ +PES RW++++ + K A+++++ A   +    P   F+  +  K + +S K P  + ++    T  +R   I S + W T ++ Y+G+ +    + GN ++N FL + VE+PA +L + +     R+ ++  + FL G  L +  ++    D  + +  + +VGK   T  +++++++ +E +PT +R   VG+SS+ +R+G+        +  Y   + ++++    +LT ++    PE+    +P +I+E+++
Sbjct:  113 CLDGWEYDKDIFLSTIVTEWDLVCKDDWKAPLTTSFFYVGVLLGSFISGQLSDRFGRKNILFLTMAMHTGFSFIQVFSVNFEMFTLLYTLVGMGHISNYVAAFVLGTEMLSKSVRIIFATLGVCIFFAFGFMVLPLFAYFIREWRRLLLAITLPGVLCGALWWFIPESPRWLISQGRIKEAEVIIRKAAKINGIVAPSTIFDPSETNKLQDDSSKKPQSHHIYDLVRTPNIRILTIMSIILWLTISVGYFGLSLDTPNLNGNIYVNCFLLAAVEVPAYVLAWLLLQHVSRRYSMAGSLFLGGSVLLLVQLVPS--DLHYLSTTLVMVGKFGITSAYSMVYVYTAELYPTVVRNMGVGVSSTASRLGSILSPYFVYLGAYDRRLPYILMGSLTILTAIITLFFPESSGVSLPETIDEMQK 529

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BLAST of slc22a-3 vs. Ensembl Mouse
Match: Slc22a5 (solute carrier family 22 (organic cation transporter), member 5 [Source:MGI Symbol;Acc:MGI:1329012])

HSP 1 Score: 157.918 bits (398), Expect = 5.394e-41
Identity = 112/425 (26.35%), Postives = 210/425 (49.41%), Query Frame = 3

Query:  498 CQNGYNYTMKYFTSSIVTEWDLVCDRAILNALATSSFFVMSFFGAIISCSIADRFGRKVVLITAFMCLNLCEFAQTYITSIYVLIVFKLLAGIFQQGCFISGFTMTIELFSLRNRSN-ACLADTFSWTXXXXXXXXXXXXXRDWRNYFFWTSITMLPFCLVFYHLPESIRWMMAKDQTKNAQILLKTATLYSNPPLPEKTFENYDKYKRKQESEKLPHYNVLHIFRETLLLRYQLINSFVWFTTAMTYYGVQVKVVEI-GNPFLNFFLSSLVEIPANILCFPIANKYGRKITIGLTNFLVGFSLFMGYILWKYLDSPWPAIIVFLVGKMLNTGIFNLIFMHVSEFFPTTLRTTAVGMSSSCARIGASFGAMIFQITLYHDSIAFVIVIGCCLLTGVLVFCLPETYRKKMPTSIEE------IKQW 1748
            C +G+ Y    F S+IVTEWDLVC       L TS FFV    G+ IS  ++DRFGRK VL           F Q +  +  +  V  +L G+ Q   +++ F +  E+ S   R   A L     + F   +L ++ YFIRDWR      ++  +    +++ +PES RW++++ + K A+++++ A   +    P   F+  +         +L H  +  + R   +    +++  +W T ++ Y+G+ +    + G+ ++N FL + VE+PA +L + +     R+ +I    FL G  L    ++   L     A++  +VGK   T  +++++++ +E +PT +R   VG+SS+ +R+G+        +  Y   + ++++    +LT +L    PE++   +P +I++      IKQW
Sbjct:  113 CLDGWEYDKDVFLSTIVTEWDLVCKDDWKAPLTTSLFFVGVLMGSFISGQLSDRFGRKNVLFLTMGMQTGFSFLQVFSVNFEMFTVLFVLVGMGQISNYVAAFVLGTEILSKSIRIIFATLGVCIFYAFGFMVLPLFAYFIRDWRMLLLALTVPGVLCGALWWFIPESPRWLISQGRIKEAEVIIRKAAKINGIVAPSTIFDPSELQDLNSTKPQLHH--IYDLIRTRNIRVITIMSIILWLTISVGYFGLSLDTPNLHGDIYVNCFLLAAVEVPAYVLAWLLLQYLPRRYSISAALFLGGSVLLFMQLVPSELFYLSTALV--MVGKFGITSAYSMVYVYTAELYPTVVRNMGVGVSSTASRLGSILSPYFVYLGAYDRFLPYILMGSLTILTAILTLFFPESFGVPLPDTIDQMLRVKGIKQW 533

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BLAST of slc22a-3 vs. UniProt/SwissProt
Match: sp|Q66KG0|S22AG_XENLA (Solute carrier family 22 member 16 OS=Xenopus laevis OX=8355 GN=slc22a16 PE=2 SV=2)

HSP 1 Score: 184.496 bits (467), Expect = 1.742e-49
Identity = 138/502 (27.49%), Postives = 228/502 (45.42%), Query Frame = 3

Query:  315 LPCVFSMYSFQFTGVKPDSFHCALPPNVS-------------RESMIPKERTGDKWEFSSCNQFQSQD----------NSTIIPCQNGYNYTMKYFTSSIVTEWDLVCDRAILNALATSSFFVMSFFGAIISCSIADRFGRKVVLITAFMCLNLCEFAQTYITSIYVLIVFKLLAGIFQQGCFISGFTMTIELFSLRNRSNACLADTFSWTXXXXXXXXXXXXXRDWRNYFFWTSITMLPFCLVFYHLPESIRWMMAKDQTKNAQILLKTATLYSNPPLPEKTFENYDKYKRK-QESEKLPHYNVLHIFRETLLLRYQLINSFVWFTTAMTYYGVQVKVVEI-GNPFLNFFLSSLVEIPANILCFPIANKYGRKITIGLTNFLVGFSLFMGYILWKYLDSPWPAIIVFLVGKMLNTGIFNLIFMHVSEFFPTTLRTTAVGMSSSCARIGASFGAMIFQITLYHDSIAFVIVIGCCLLTGVLVFCLPETYRKKMPTSIEEIKQ 1745
            L  VF   + +F    P +    L PN S             ++ ++ ++  GD WE + C++ + +D          N T+  C NGY+Y      SSIVTEWDLVCDR  L  L    F +    GA+I   IADR GR+ ++        L   A  +    Y  ++ + L  +   G ++  F    E   ++ R+ A +     +     I+ +  + +R W  Y    S+T LPF L  + LPE+  W+ ++ + K  + L++T   ++    P K  E     +    +   L ++NVL +F      R  +    +WFT ++ YY   +  V + GN +LN FL+  VEIP+ I+     +K GR+ T  L  FL+  ++  G I+    D     I + + GK      F LI+++ +E +PT +R+ AVG  S   RIG+        +T     +  ++V     LTG+L   LPET    + +++EE  +
Sbjct:   34 LASVFIAVTPKFICRAPGNISTVLLPNASTLRLEDAWESWTSKDYLVVQQENGDIWELNQCSRLKREDASYLTYFYDGNKTLFSCSNGYHYDKSNLESSIVTEWDLVCDREWLAKLIQPIFMLGVLIGAVIFGDIADRVGRRPIIWITSTGQFLFGIAVAFTFDYYSFVIVRFLLAMVSSGYYVVVFVYLTEYVGIKARTWASMHVHAFFAVGVMIVSLVGFLVRTWWIYQIILSLTTLPFVLCCWMLPETPFWLYSQGKYKEVEKLIRTIEKWNKISTPCKLSELCPAQETHVDQPNTLKNHNVLDLFYNWSFARRTITVWLIWFTGSLGYYVFALNSVNLGGNEYLNLFLTGAVEIPSYIVACLGMDKIGRRNT--LAPFLIISAVICGVIMLIPQDHSTVTIAMSMAGKFSIAVAFGLIYLYTAELYPTIVRSLAVGSGSMMCRIGSVVAPFCVYLTDVWIFMPQMLVGIMAFLTGILTLTLPETLGIPLTSTMEEAAE 533

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BLAST of slc22a-3 vs. UniProt/SwissProt
Match: sp|A6QLW8|S22A7_BOVIN (Solute carrier family 22 member 7 OS=Bos taurus OX=9913 GN=SLC22A7 PE=2 SV=1)

HSP 1 Score: 181.03 bits (458), Expect = 2.091e-48
Identity = 147/547 (26.87%), Postives = 253/547 (46.25%), Query Frame = 3

Query:  237 EKCLDELGG------KNIWILKW--------FLLISFMKSLPCVFSMYSFQFTGVKPDSFHCALPPNVSRESMIPKERTGDKWEFSSCNQF---QSQDNSTI-----------------IPCQNGYNYTMKYFTSSIVTEWDLVCDRAILNALATSSFFVMSFFGAIISCSIADRFGRKVVLITAFMCLNLCEFAQTYITSIYVLIVFKLLAGIFQQGCFISGFTMTIELFSLRNRSNACLADTFSWTXXXXXXXXXXXXXRDWRNYFFWTSITMLPFCLVFYHLPESIRWMMAKDQTKNAQILLKTATLYSNPPLPEKTF--ENYDKYKRKQESEKLPHYNVLHIFRETLLLRYQLINSFVWFTTAMTYYGVQVKVVEIGNPFLNFFLSSL----VEIPANILCFPIANKYGRKITIGLTNFLVGFSLFMGYILWKYLDSP----WPAIIVFLVGKMLNTGIFNLIFMHVSEFFPTTLRTTAVGMSSSCARIGASFGAMIFQITLYHDSIAFVIVIGCCLLTGVLVFCLPETYRKKMPTSIEEIKQ 1745
            E+ LD++GG      +N+ +L          FLL  F+ ++P     +     GV PD+F      +   E+ +P+E  G     S+C +F   Q+  NST+                 +PC  G+ Y    F+S+I TEWDLVC++  LN   ++ FF     GA +   ++DRFGR+ +L+ A++       A     S  +  + + L G+   G  I    + +E   +R+R+ A +  +  WT    +L +  Y IRDWR      ++  +P  L  + +PES RW++ + + + A   L      + PP+ E +   E  +K    +   + P Y  L +FR   L    L    VWF    +YYGV + +  +G   LN +L+ L    VE+P+ +L +      GR++T+  T  L+G +L +G    + L SP    W   +  + GK  +   F   ++  SE +PT LR T +G+++   R+G S   +   +     S+  +   G  LL       LPET + ++P +I+++++
Sbjct:    4 EELLDKVGGFGPFQLRNVALLALPRVLLPMHFLLPIFLAAVPA----HRCALPGV-PDNFSNE---DAWLEAHLPREPDG---RLSACLRFTHPQALPNSTLWGEGQNSGEQPEGEPSTVPCPQGWEYNHSEFSSTIATEWDLVCEQKGLNKAISTFFFAGVLVGAEVYGYLSDRFGRRRLLLVAYVSSLALGLASAASVSYIMFAITRTLTGMALAGFTIIVMPLELEWLDVRHRTVAGVLSSTFWTGGVMLLALIGYLIRDWRWLLLTVTLPCVPGILTLWWVPESARWLLTQGRVEEAHRYLLRCARLNGPPVGEDSLSREALNKVAAAERMVRRPSY--LDLFRTPRLRYISLCCMVVWFGVNFSYYGVSLDLSGLG---LNVYLTQLVFGAVELPSKLLVYLSVRHAGRRLTMAGT--LLGAALAVGL---RILVSPEMKSWSTALAVM-GKAFSEAAFTTAYLFTSELYPTVLRQTGMGLTALVGRLGGSLAPLAALLDGVWLSLPKLAYGGIALLAACTALLLPETKQAQLPETIQDVER 528

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BLAST of slc22a-3 vs. UniProt/SwissProt
Match: sp|Q5RLM2|S22A7_RAT (Solute carrier family 22 member 7 OS=Rattus norvegicus OX=10116 GN=Slc22a7 PE=1 SV=1)

HSP 1 Score: 178.718 bits (452), Expect = 1.264e-47
Identity = 140/537 (26.07%), Postives = 252/537 (46.93%), Query Frame = 3

Query:  228 MDPEKCLDELGGKNIWILKWFLLISFMKSL-PCVFSMYSFQFTGVKPDSFHCALP---PNVSR-----ESMIPKERTGDKWEFSSCNQF---QSQDNSTI----------------IPCQNGYNYTMKYFTSSIVTEWDLVCDRAILNALATSSFFVMSFFGAIISCSIADRFGRKVVLITAFMCLNLCEFAQTYITSIYVLIVFKLLAGIFQQGCFISGFTMTIELFSLRNRSNACLADTFSWTXXXXXXXXXXXXXRDWRNYFFWTSITMLPFCLVFYHLPESIRWMMAKDQTKNAQILLKTATLYSNPPLPEKTF--ENYDKYKRKQESEKLPHYNVLHIFRETLLLRYQLINSFVWFTTAMTYYGVQVKVVEIG-NPFLNFFLSSLVEIPANILCFPIANKYGRKITIGLTNFLVGFSLFMGYILWKYLDSPWPAIIVFLVGKMLNTGIFNLIFMHVSEFFPTTLRTTAVGMSSSCARIGASFGAMIFQITLYHDSIAFVIVIGCCLLTGVLVFCLPETYRKKMPTSIEEIKQ 1745
            M  E  LD++GG   + L+  +L++  + L P  F +  F        + HCALP    N+S      E+ +P+E  G    FSSC +F   Q+  N T+                +PC  G+ Y    F+S+I TEWDLVC +  LN + ++ FF+    GA++   ++DRFGR+ +L+ A++   +         +  + +V + L G    G  I    + +E   + +R+ A +  T  W+    +L +  Y IR WR      ++  +P  +  + +PES RW++ + + + A+  L +    +  P+ E +   E  +     + + + P Y  L +FR + L    L    VWF    +YYG+ + V  +G N +    L   VE+P+ I+ + +  + GR++T      L+G +L  G  L   L++      + +VGK  +   F   ++  SE +PT LR T +G+++   R+GAS   +   +      +  V   G  L+       LPET + ++P +I+++++
Sbjct:    1 MGFEDLLDKVGGFGPFQLRNLVLMALPRMLLPMHFLLPVFM---AAVPAHHCALPGAPANLSHQDLWLEAHLPRETDGS---FSSCLRFAYPQTVPNVTLGTEVSNSGEPEGEPLTVPCSQGWEYDRSEFSSTIATEWDLVCQQRGLNKITSTCFFIGVLVGAVVYGYLSDRFGRRRLLLVAYVSSLVLGLMSAASINYIMFVVTRTLTGSALAGFTIIVLPLELEWLDVEHRTVAGVISTVFWSGGVLLLALVGYLIRSWRWLLLAATLPCVPGIISIWWVPESARWLLTQGRVEEAKKYLLSCAKLNGRPVGEGSLSQEALNNVVTMERALQRPSY--LDLFRTSQLRHISLCCMMVWFGVNFSYYGLTLDVSGLGLNVYQTQLLFGAVELPSKIMVYFLVRRLGRRLTE--AGMLLGAALTFGTSLLVSLETKSWITALVVVGKAFSEAAFTTAYLFTSELYPTVLRQTGLGLTALMGRLGASLAPLAALLDGVWLLLPKVAYGGIALVAACTALLLPETKKAQLPETIQDVER 527

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BLAST of slc22a-3 vs. UniProt/SwissProt
Match: sp|Q91WU2|S22A7_MOUSE (Solute carrier family 22 member 7 OS=Mus musculus OX=10090 GN=Slc22a7 PE=1 SV=1)

HSP 1 Score: 177.948 bits (450), Expect = 2.793e-47
Identity = 135/537 (25.14%), Postives = 245/537 (45.62%), Query Frame = 3

Query:  228 MDPEKCLDELGGKNIWILKWFLLISFMK-SLPCVFSMYSFQFTGVKPDSFHCALP---PNVSRESM-----IPKERTGDKWEFSSCNQF---QSQDNSTI----------------IPCQNGYNYTMKYFTSSIVTEWDLVCDRAILNALATSSFFVMSFFGAIISCSIADRFGRKVVLITAFMCLNLCEFAQTYITSIYVLIVFKLLAGIFQQGCFISGFTMTIELFSLRNRSNACLADTFSWTXXXXXXXXXXXXXRDWRNYFFWTSITMLPFCLVFYHLPESIRWMMAKDQTKNAQILLKTATLYSNPPLPEKTF--ENYDKYKRKQESEKLPHYNVLHIFRETLLLRYQLINSFVWFTTAMTYYGVQVKVVEIG-NPFLNFFLSSLVEIPANILCFPIANKYGRKITIGLTNFLVGFSLFMGYILWKYLDSPWPAIIVFLVGKMLNTGIFNLIFMHVSEFFPTTLRTTAVGMSSSCARIGASFGAMIFQITLYHDSIAFVIVIGCCLLTGVLVFCLPETYRKKMPTSIEEIKQ 1745
            M  E+ L ++GG   + L+  +L++  +  LP  F +  F        + HCALP    N+S + +     +P+E  G    FSSC +F   Q+  N T+                +PC  G+ Y    F+S+I TEWDLVC++  LN + ++ FF+    GA++   ++DRFGR+ +L+ A++             +  + +  ++L G    G  I    + +E   + +R+ A +  T  WT    +L +  Y IR WR      ++  +P  +  + +PES RW++ + + + A+  L      +  P+ E +   E  +K    +   + P Y  L +FR + L    L    +WF    +YYG+ +    +G   +    L   VE+P+ I  F +    GR++T      L+  +L  G  L    D+      + ++GK  +   F   ++  SE +PT LR T +G ++   R+GAS   ++  +      +  +   G   L    V  LPET + ++P +I+++++
Sbjct:    1 MGFEELLHKVGGFGPFQLRNLVLLALPRFLLPMHFLLPIFM---AAVPAHHCALPDAPANLSHQDLWLKTHLPRETDGS---FSSCLRFAYPQALPNVTLGTEVYNSGEPEGEPLTVPCSQGWEYDRSEFSSTIATEWDLVCEQRGLNKVTSTCFFIGVLLGAVVYGYLSDRFGRRRLLLVAYVSTLALGLMSAASVNYIMFVTTRMLTGSALAGFTIIVLPLELEWLDVEHRTVAGVISTTFWTGGVLLLTLVGYLIRSWRWLLLAATLPCVPGIISIWWVPESARWLLTQGRVEEAKKYLSICAKLNGRPISEDSLSQEALNKVITMERVSQRPSY--LDLFRTSQLRHVSLCCMMMWFGVNFSYYGLTLDASGLGLTVYQTQLLFGAVEVPSKITVFFLVRLVGRRLTEA--GMLLATALTFGISLLVSSDTKSWITALVVIGKAFSEAAFTTAYLFTSELYPTVLRQTGMGFTALIGRLGASLAPLVVLLDGVWLLLPKLAYGGISFLAACTVLLLPETKKAQLPETIQDVER 527

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BLAST of slc22a-3 vs. UniProt/SwissProt
Match: sp|Q3YAW7|S22A7_RABIT (Solute carrier family 22 member 7 OS=Oryctolagus cuniculus OX=9986 GN=SLC22A7 PE=2 SV=1)

HSP 1 Score: 177.563 bits (449), Expect = 3.704e-47
Identity = 144/535 (26.92%), Postives = 243/535 (45.42%), Query Frame = 3

Query:  237 EKCLDELGGKNIWILKWFLLISFMK-SLPCVFSMYSFQFTGVKPDSFHCALPPNVSR--------ESMIPKERTGDKWEFSSCNQFQS-------------------QDNSTIIPCQNGYNYTMKYFTSSIVTEWDLVCDRAILNALATSSFFVMSFFGAIISCSIADRFGRKVVLITAFMCLNLCEFAQTYITSIYVLIVFKLLAGIFQQGCFISGFTMTIELFSLRNRSNACLADTFSWTXXXXXXXXXXXXXRDWRNYFFWTSITMLPFCLVFYHLPESIRWMMAKDQTKNAQ-ILLKTATLYSNP-PLPEKTFENYDKYKRKQESEKLPHYNVLHIFRETLLLRYQLINSFVWFTTAMTYYGVQVKVVEIG-NPFLNFFLSSLVEIPANILCFPIANKYGRKITIGLTNFLVGFSLFMG-YILWKYLDSPWPAIIVFLVGKMLNTGIFNLIFMHVSEFFPTTLRTTAVGMSSSCARIGASFGAMIFQITLYHDSIAFVIVIGCCLLTGVLVFCLPETYRKKMPTSIEEIKQ 1745
            E+ L+++GG   + L+   L++  +  LP  F +  F        +  CALP   +         E+ +P+E  G    FSSC +F                     Q N + +PC  G+ Y    F+S+I TEWDLVC++  L+  A++ FFV    GA+    ++DRFGR+ +L+ A++   +   A     S  +  + + L G    G  I    + +E   + +R  A +  +  WT    +L +  Y IRDWR      ++ + P  L  + +PES RW++ + + + AQ  LL+ A L   P P    + E   +    +   + P Y  L +FR   L    L    VWF    +YYG  + V  +G N +    L   VE+P+ +L +      GR++T   T  L+G +L +G  +L     S W   +  + GK  +   F   ++  SE +PT LR T +G+++   R+G S   +   +     S+  +   G  LL       LPET R ++P +I+++++
Sbjct:    4 EELLEQVGGFGPFQLRNLALLALPRILLPLHFLLPVFL---AAVPAHRCALPGTPANLSFQDAWLEAYLPREADGT---FSSCLRFTHPQAVPNITLGREGRSPGDLQGNRSSMPCTQGWEYDRSEFSSTIATEWDLVCEQKDLSRAASTFFFVGVLVGAVAFGYLSDRFGRRRLLLVAYVSALVLGLASAASVSYVMFAITRTLTGSALAGFTIIVMPLELEWLDVEHRIVAGVLSSTFWTGGVMLLALVGYLIRDWRWLLLAVTLPLAPGILSLWWVPESARWLLTQGRVEEAQRYLLRCARLNGRPVPQDGLSREALSEVAAGERVVRRPSY--LDLFRTPRLRHISLCCMVVWFGVNFSYYGQSLAVSGLGLNVYQTQLLFGAVELPSKLLVYLSVRHAGRRLTQAGT--LMGAALALGIRLLVASERSSWSTALAVM-GKGFSEAAFTTAYLFTSELYPTVLRQTGMGLTALVGRLGGSLAPLAALLDGVWLSLPKLAYGGIALLAACTALLLPETRRAQLPETIQDVER 527

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BLAST of slc22a-3 vs. TrEMBL
Match: A0A0H3YJ39 (Slc22a-3 OS=Schmidtea mediterranea OX=79327 GN=slc22a-3 PE=2 SV=1)

HSP 1 Score: 1037.71 bits (2682), Expect = 0.000e+0
Identity = 517/517 (100.00%), Postives = 517/517 (100.00%), Query Frame = 3

Query:  228 MDPEKCLDELGGKNIWILKWFLLISFMKSLPCVFSMYSFQFTGVKPDSFHCALPPNVSRESMIPKERTGDKWEFSSCNQFQSQDNSTIIPCQNGYNYTMKYFTSSIVTEWDLVCDRAILNALATSSFFVMSFFGAIISCSIADRFGRKVVLITAFMCLNLCEFAQTYITSIYVLIVFKLLAGIFQQGCFISGFTMTIELFSLRNRSNACLADTFSWTXXXXXXXXXXXXXRDWRNYFFWTSITMLPFCLVFYHLPESIRWMMAKDQTKNAQILLKTATLYSNPPLPEKTFENYDKYKRKQESEKLPHYNVLHIFRETLLLRYQLINSFVWFTTAMTYYGVQVKVVEIGNPFLNFFLSSLVEIPANILCFPIANKYGRKITIGLTNFLVGFSLFMGYILWKYLDSPWPAIIVFLVGKMLNTGIFNLIFMHVSEFFPTTLRTTAVGMSSSCARIGASFGAMIFQITLYHDSIAFVIVIGCCLLTGVLVFCLPETYRKKMPTSIEEIKQWVAHKPIISFH 1778
            MDPEKCLDELGGKNIWILKWFLLISFMKSLPCVFSMYSFQFTGVKPDSFHCALPPNVSRESMIPKERTGDKWEFSSCNQFQSQDNSTIIPCQNGYNYTMKYFTSSIVTEWDLVCDRAILNALATSSFFVMSFFGAIISCSIADRFGRKVVLITAFMCLNLCEFAQTYITSIYVLIVFKLLAGIFQQGCFISGFTMTIELFSLRNRSNACLADTFSWTFSSFILIIYIYFIRDWRNYFFWTSITMLPFCLVFYHLPESIRWMMAKDQTKNAQILLKTATLYSNPPLPEKTFENYDKYKRKQESEKLPHYNVLHIFRETLLLRYQLINSFVWFTTAMTYYGVQVKVVEIGNPFLNFFLSSLVEIPANILCFPIANKYGRKITIGLTNFLVGFSLFMGYILWKYLDSPWPAIIVFLVGKMLNTGIFNLIFMHVSEFFPTTLRTTAVGMSSSCARIGASFGAMIFQITLYHDSIAFVIVIGCCLLTGVLVFCLPETYRKKMPTSIEEIKQWVAHKPIISFH
Sbjct:    1 MDPEKCLDELGGKNIWILKWFLLISFMKSLPCVFSMYSFQFTGVKPDSFHCALPPNVSRESMIPKERTGDKWEFSSCNQFQSQDNSTIIPCQNGYNYTMKYFTSSIVTEWDLVCDRAILNALATSSFFVMSFFGAIISCSIADRFGRKVVLITAFMCLNLCEFAQTYITSIYVLIVFKLLAGIFQQGCFISGFTMTIELFSLRNRSNACLADTFSWTFSSFILIIYIYFIRDWRNYFFWTSITMLPFCLVFYHLPESIRWMMAKDQTKNAQILLKTATLYSNPPLPEKTFENYDKYKRKQESEKLPHYNVLHIFRETLLLRYQLINSFVWFTTAMTYYGVQVKVVEIGNPFLNFFLSSLVEIPANILCFPIANKYGRKITIGLTNFLVGFSLFMGYILWKYLDSPWPAIIVFLVGKMLNTGIFNLIFMHVSEFFPTTLRTTAVGMSSSCARIGASFGAMIFQITLYHDSIAFVIVIGCCLLTGVLVFCLPETYRKKMPTSIEEIKQWVAHKPIISFH 517

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BLAST of slc22a-3 vs. TrEMBL
Match: C3ZR16 (MFS domain-containing protein OS=Branchiostoma floridae OX=7739 GN=BRAFLDRAFT_87519 PE=4 SV=1)

HSP 1 Score: 212.616 bits (540), Expect = 6.387e-58
Identity = 137/493 (27.79%), Postives = 235/493 (47.67%), Query Frame = 3

Query:  333 MYSFQFTGVKPDSFHCALPPNVSR----------ESMIPKERTGDKWEFSSC------NQFQSQDNSTIIPCQNGYNYTMKYFTSSIVTEWDLVCDRAILNALATSSFFVMSFFGAIISCSIADRFGRKVVLITAFMCLNLCEFAQTYITSIYVLIVFKLLAGIFQQGCFISGFTMTIELFSLRNRSNACLADTFSWTXXXXXXXXXXXXXRDWRNYFFWTSITMLPFCLVFYHLPESIRWMMAKDQTKNAQILLKTATLYSNPPLPEKTFENY-DKYKRKQESEKLPHYNVLHIFRETLLLRYQLINSFVWFTTAMTYYGVQVKVVEI-GNPFLNFFLSSLVEIPANILCFPIANKYGRKITIGLTNFLVGFSLFMGYILWKYLDSPWPAIIVF----LVGKMLNTGIFNLIFMHVSEFFPTTLRTTAVGMSSSCARIGASFGAMIFQITLYHDSIAFVIVIGCCLLTGVLVFCLPETYRKKMPTSIEEIKQ 1745
            M++  F    P + HC L PN S            S +P E  G +W +SSC      ++  ++ N T   C +G+ Y    + S++VT++DLVC+R  L  L  S F V    G +IS + +DRFGR+  ++   +   +   A  + T     +V +LLAG    G F  G T+ IE+     R+   +  + SW   +  L    YF+RDW +     S+  +P    ++ LPES RW+++ ++ K A+I ++ A  ++   +P++ ++    K K K+  EK   Y+++ +FR   L R+ +  S VWF T + YY + +   ++ G+P+LNF L +L+E   + +      K+GR+  +G      GF    G        +P     V     L+G+      FN + M+  E  PT +RT  VG+++  +R G      +  +      +  +     C L G  VF LPET+   +P ++E+ ++
Sbjct:    1 MFAQAFLAATP-AHHCRLYPNDSSAMYGHPSERLNSSVPMENVGGRWRYSSCLMHNGTSETSTESNQTAT-CNHGWEYDQSVYHSTVVTDYDLVCERHWLKELGQSIFMVGVAAGGLISGTTSDRFGRRPTVVACIILQLISGLAAAFTTDYVTFLVLRLLAGGAANGAFYVGLTLGIEVIGSSKRNVVGMTISSSWNPGAVFLAGLAYFLRDWWSLQLAVSLMSVPLLSYWWLLPESPRWLLSNNRIKKAKISIQKAAKFNRVTIPDEVYDKVITKAKDKEPGEKFKKYSLVDLFRGPRLRRFTVTVSLVWFATVVVYYALIIGSADLAGDPYLNFVLGALLEWGLSFVGLVAMEKWGRRPVVG------GFLFLTGAACLAVASTPTERQDVIRYISLLGRCAIGVAFNCLAMYSPEVLPTVVRTMGVGVANMWSRAGGILSPFVSLLADVWPPLPMLTFGILCTLGGAGVFSLPETFGIPLPDTLEDGEK 485

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BLAST of slc22a-3 vs. TrEMBL
Match: R7UIT7 (MFS domain-containing protein (Fragment) OS=Capitella teleta OX=283909 GN=CAPTEDRAFT_63021 PE=4 SV=1)

HSP 1 Score: 209.92 bits (533), Expect = 1.485e-57
Identity = 130/418 (31.10%), Postives = 219/418 (52.39%), Query Frame = 3

Query:  540 SIVTEWDLVCDRAILNALATSSFFVMSFFGAIISCSIADRFGRKVVLITAFMCLNLCEFAQTYITSIYVLIVFKLLAGIFQQGCFISGFTMTIELFSLRNRSNACLADTFSWTXXXXXXXXXXXXXRDWRNYFFWTSITMLPFCLVFYHLPESIRWMMAKDQTKNAQILLKTATLYSNPPLPEKT-FEN--YDKYK--RKQESEKLPHYNVLHIFRETLLLRYQLINSFVWFTTAMTYYGVQVKVVEI-GNPFLNFFLSSLVEIPANILCFPIANKYGRKITIGLTNFLVGF----SLFMGYILWKYLDSPWPAIIVFLVGKMLNTGIFNLIFMHVSEFFPTTLRTTAVGMSSSCARIGASFGAMIFQITLYHDSIAFVIVIGCCLLTGVLVFCLPETYRKKMPTSIEEIKQWVAHKP 1763
            SI ++W+LVCDR  +  ++ +        GA+    ++D FGRK + + + M + +      ++ + Y   VF+  AG  QQG  ++GF M  ELF  + R+ A +A    W     +L ++ Y IR+WR+     S+  L    +F+ LPESI W+ A  + + A+ +++ A  ++N P+P+++ F +   DK++  RK+   +   Y +L + R   LL Y  +  F+W    + YYG+      + G+ +LNFFLS LVEIPA   C  I  ++GR+  + + +F+ G     ++F+  +     D  W  I   ++GK   TG F +IF++  E FPTTLR  A+G++S   RIG         +      +  ++     L  G+LVF LPET  + +P +IE+I+ W + KP
Sbjct:    3 SIFSQWNLVCDRRFMKDMSQTIMVFGVMVGAMGFTMLSDNFGRKPIFLFSHMAMVVVGCITAFLNNYYAFCVFRFFAGALQQGIILTGFVMACELFPAKYRTFAGMAIENFWATGMCLLALWAYLIRNWRHLQLLISLLGLFAVPLFWFLPESIPWLCANQRVEEAEEIIQKAAKFNNVPMPKRSKFPSSIIDKFRQTRKKSGPEAARYTLLDVLRNRRLLSYATMMCFIWLVNNLVYYGLSFSTSALAGDRYLNFFLSGLVEIPAYTSCIFILERFGRRWPLCIFHFIAGLFLAVTMFIPEVTEGGTDLRWLLITCNMIGKFGITGTFGIIFLYTPEIFPTTLRAQAMGIASLGGRIGNMMAPFADSLAAAVPWLPGILFGALSLAAGLLVFFLPETLNRPLPQTIEDIENW-SKKP 419

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BLAST of slc22a-3 vs. TrEMBL
Match: A0A3P8XC61 (MFS domain-containing protein OS=Esox lucius OX=8010 PE=4 SV=1)

HSP 1 Score: 209.92 bits (533), Expect = 1.609e-56
Identity = 151/541 (27.91%), Postives = 264/541 (48.80%), Query Frame = 3

Query:  204 RINSSRLEMDPEKCLDELGGKNIWILKWF-LLISFMKSLPCVFSMYSF---QFTGVKPDSFHCALPP-----NVSRESM----IPKERTGDKWEFSSCNQF---------QSQDNSTI-IPCQNGYNYTMKYFTSSIVTEWDLVCDRAILNALATSSFFVMSFFGAIISCSIADRFGRKVVLITAFMCLNLCEFAQTYITSIYVLIVFKLLAGIFQQGCFISGFTMTIELFSLRNRSNACLADTFSWTXXXXXXXXXXXXXRDWRNYFFWTSITMLPFCLVFYHLPESIRWMMAKDQTKNAQILLKTATLYSNPP--LPEKTFENYDKYKRKQESEKLPHYNVLHIFRETLLLRYQLINSFVWFTTAMTYYGVQVKVVEIG-NPFLNFFLSSLVEIPANILCFPIANKYGRKITIGLTNFLVGFSLFMGYILWKYLDSPWP-AIIVFLVGKMLNTGIFNLIFMHVSEFFPTTLRTTAVGMSSSCARIGASFGAMIFQITLYHDSIAFVIVIGCCLLTGVLVFCLPETYRKKMPTSIEEIKQ 1745
            R +S  L M  E  L+E  G       WF +LI  +  +P V   ++F    F    P + HCAL       N+++E      +P E  G     SSC  F            D+  + +PCQNG+ Y    F S+I TEWDLVC+R  +N +  + FFV    GAI   +++D+FGRK +L+ +++   +  F+  +  S  + IV + L G    G  I    +++E   +++R+   ++ + +W+  + +L    Y + DWR      S+ +    + ++ LPES RW++A  + + A + L+    ++N    L +   E+        +S K   Y+ L + R   + R  L+   VW+  A TYYG+ + +   G + +L  F+ S +EIPA I+ +   + +GRK+    T  L G  + +   + K     W    IV ++GK L+   F  + +H +E +PT +R   +G ++  AR+G S   +I  +      +  VI+    +L+G++ F LPET+  ++P +IE+I++
Sbjct:    3 RGDSRMLRMKFENILEETDG-----CGWFQILIITLLCVPRVILPFNFLLHNFIAAVP-AHHCALDDAGVIRNLTQEQRLTVSVPVEEDGTP---SSCKMFLEPQFHLLINPNDSDLVKVPCQNGWVYDNSTFKSTIATEWDLVCNRTAMNKVTATIFFVGVMMGAIAFGTLSDKFGRKPMLLVSYILSIVFGFSCAFSNSYTMFIVMRFLTGFGLTGISIISTVLSVEWVDIKHRALIGISGSLAWSVGNIMLAGIAYQVNDWRLLMIAVSVPLSLAIVTWWWLPESARWLIANGEVEKAHLYLQKCAYFNNKKDFLSKIKPEDLSNVVVVDKSNK--TYSYLDLVRTPKMRRLALLTGIVWYGVASTYYGISLNITGFGLSVYLTHFIFSAIEIPAKIIVYFCLDTFGRKLCQASTLLLAGTCIAINMFVPK---GQWHLRTIVAVLGKGLSEASFTTVILHTTEIYPTVVRQNGLGYTNFMARLGVSIAPLIILLEEVWKPLPEVIICCVSILSGLVAFLLPETHNVRLPETIEDIEK 529

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BLAST of slc22a-3 vs. TrEMBL
Match: A0A093JNL3 (Solute carrier family 22 member 7 (Fragment) OS=Struthio camelus australis OX=441894 GN=N308_05817 PE=4 SV=1)

HSP 1 Score: 205.682 bits (522), Expect = 3.658e-55
Identity = 149/533 (27.95%), Postives = 258/533 (48.41%), Query Frame = 3

Query:  228 MDPEKCLDELGG-KNIWILKWFLLISFMKSLPCVFSMYSFQFTGVKPDSFHCALPP-----NVSRESM----IPKERTGDKWEFSSCNQF--------------QSQDNSTIIPCQNGYNYTMKYFTSSIVTEWDLVCDRAILNALATSSFFVMSFFGAIISCSIADRFGRKVVLITAFMCLNLCEFAQTYITSIYVLIVFKLLAGIFQQGCFISGFTMTIELFSLRNRSNACLADTFSWTXXXXXXXXXXXXXRDWRNYFFWTSITMLPFCLVFYHLPESIRWMMAKDQTKNA-QILLKTATLYSNPPLPEKTFENYDKYKRKQESEKL--PHYNVLHIFRETLLLRYQLINSFVWFTTAMTYYGVQVKVVEIG-NPFLNFFLSSLVEIPANILCFPIANKYGRKITIGLTNFLVGFSLFMGYILWKYLDSPWPAIIVFLVGKMLNTGIFNLIFMHVSEFFPTTLRTTAVGMSSSCARIGASFGAMIFQITLYHDSIAFVIVIGCCLLTGVLVFCLPETYRKKMPTSIEEIK 1742
            M  E  L E GG     IL  FLL     +LP  F +++F        S HCA+P      N++ E +    +P+E  G    F SC  F              Q +++S I  C++G+ Y    FTS+  T+WDLVC++  LN    + FF+    GA+I   ++DR+GRK +L+ + +C  +        TS  +L + + L G+   G  +    + +E   +++R+ + +  +  W+  + +L +  Y +RDWR      +    P  +  + +PES RW++A  + K A + LL+ A +        K F    +  R+  +EK    +Y+ + +FR  +L +  L +  VWF  A +YYG+ + +   G N +L+ F+  ++EIPA ++ + + N+ GR+ +   T  L G  +    I+ K   S     +V ++GK  +   F  +F++ SE +PT LR   +G +S  ARIG +   ++F +     S+  V   G  +  G + F LPET    +P  IE+++
Sbjct:    1 MKFEDLLLETGGFGRFQILILFLLCFPRINLPMHFLLHNFL---AATPSHHCAIPHQEAFVNLTTEELLLISVPREPDGT---FRSCEMFSQPQFYLLLLNSSLQPENDSLIEDCKHGWVYDHSQFTSTTATQWDLVCEQRGLNQATATFFFIGVTVGAVIFGYLSDRYGRKAMLLVSLVCSGMFGMLSAASTSYSMLAITRTLTGVALSGISLIILPLGMEWVDVQHRTLSGILTSIFWSIGNMLLAMVAYLVRDWRWLLVAVTGPCFPSIICLWWVPESARWLIANGKVKQAHRHLLRCARMNG-----RKDFAVSPEALRRMTTEKKSGENYSYISLFRTPVLRKISLCSGAVWFGVAFSYYGMSLNLTGFGLNMYLSQFVFGIIEIPAKLIMYVLVNRVGRRQSQAWTLILAGLCIGANVIIPKSFTS--MRSVVAIMGKGFSESAFTTVFLYTSELYPTILRQNGMGYTSFVARIGGALAPLVFLLDDVWRSLPEVTYCGVAVCCGSVAFLLPETLNVHLPEGIEDVE 520

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BLAST of slc22a-3 vs. Ensembl Cavefish
Match: ENSAMXT00000010878.2 (pep primary_assembly:Astyanax_mexicanus-2.0:14:29265439:29284025:-1 gene:ENSAMXG00000010589.2 transcript:ENSAMXT00000010878.2 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 191.815 bits (486), Expect = 5.293e-53
Identity = 137/517 (26.50%), Postives = 253/517 (48.94%), Query Frame = 3

Query:  279 LKWFLLISFMKSLPCVFSMYSFQFTGVKPDSFHCALP-PNVSRE---SMIPKERTGDKWEFSSCNQFQSQ-----------------DNSTIIPCQNGYNYTMKYFTSSIVTEWDLVCDRAILNALATSSFFVMSFFGAIISCSIADRFGRKVVLITAFMCLNLCEFAQTYITSIYVLIVFKLLAGIFQQGCFISGFTMTIELFSLRNRS-----NACLADTFSWTXXXXXXXXXXXXXRDWRNYFFWTSITMLPFCLVFYHLPESIRWMMAKDQTKNAQILLKTATLYSNPPLPEKTFENYDKYKRKQESEKL-PHYNVLHIFRETLLLRYQLINSFVWFTTAMTYYGVQVKVVEI-GNPFLNFFLSSLVEIPANILCFPIANKYGRKITIGLTNFLVGFSLFMGYILWKYLDSPWPAIIVFLVGKMLNTGIFNLIFMHVSEFFPTTLRTTAVGMSSSCARIGASFGAMIFQITLYHDSIAFVIVIGCCLLTGVLVFCLPETYRKKMPTSIEEIKQ 1745
            L +FLL S   ++P  FS +S  F    P + HC +P  N+S E   + IP      K E S C ++  +                  +  +  C +G+ Y+   + S+IVTE+DLVCD        +S +F+    G+  S  I+DRFGRK VL    M   +  F Q +  S  V  +   + G+ Q   +++ F +  EL S   R        CL   F +     +L +  Y IR+WR      S+  L +  +++ +PES RW++++ + + A+ ++K A   +    P+  F+  ++ ++  + +K  P  N+L + R + + R  LI   VW T +M Y+G+ +    + G+ ++N F+S+ +E+PA I  +       RK++  ++  L G  L+  +I     D P  ++ + + GK        L+F +  E +PT LR TAVG  +  +R+G++       +++YH  + ++++   C+ + +    LPET+R+ +P +I+++++
Sbjct:   38 LIFFLLCS--STIPNGFSAFSVIFLADIP-AHHCLIPGANLSEEWIRASIPLNVVNGKHELSKCRRYNQEIIRNLSAQGFNPEDVNLTSVELEKCTDGWTYSKDVYQSTIVTEFDLVCDDEWKQPFTSSIYFIGVLCGSFFSGQISDRFGRKPVLFATMMVQTIFTFIQVFAPSWEVFSILFFIVGLGQISNYVAAFVLGTELLSGGVRVFYSSLGVCLFFAFGY----MMLPLIAYLIRNWRMLLVALSVPGLIYIPLWWFIPESPRWLISQGRVEEAEAIVKNAARKNGVLPPDIIFKKSEEEEKNTKPQKTKPENNILDLMRTSNIRRTTLILFLVWLTLSMGYFGLSLNTSRLHGDSYVNCFISAALEVPAYITSWLSLRYLPRKLSCPVSMLLGGGVLY--FIQLVPPDLPALSVALEMAGKFGMAIGTALMFAYTGELYPTVLRNTAVGSCAMVSRVGSAVAPYFIHLSVYHKYLPYILLGTLCIFSSLTTLFLPETFRRPLPETIDQMQK 545

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BLAST of slc22a-3 vs. Ensembl Cavefish
Match: ENSAMXT00000043421.1 (pep primary_assembly:Astyanax_mexicanus-2.0:APWO02001371.1:10938:20593:-1 gene:ENSAMXG00000011796.2 transcript:ENSAMXT00000043421.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 183.341 bits (464), Expect = 2.662e-50
Identity = 131/521 (25.14%), Postives = 247/521 (47.41%), Query Frame = 3

Query:  237 EKCLDELGGKNIWILKWFLLISFMKS-LPCVFSMYSFQFTGVKPDSFHCALP-------PNVSRESMIPKERTGDKWEFSSCNQFQSQDN--------STIIPCQNGYNYTMKYFTSSIVTEWDLVCDRAILNALATSSFFVMSFFGAIISCSIADRFGRKVVLITAFMCLNLCEFAQTYITSIYVLIVFKLLAGIFQQGCFISGFTMTIELFSLRNRSNACLADTFSWTXXXXXXXXXXXXXRDWRNYFFWTSITMLPFCLVFYHLPESIRWMMAKDQTKNAQ-ILLKTATLYSNPPLPEKTFENYDKYKRKQESEKLPHYNVLHIFRETLLLRYQLINSFVWFTTAMTYYGVQVKVVEIG-NPFLNFFLSSLVEIPANILCFPIANKYGRKITIGLTNFLVGFSLFMGYILWKYLDSPWPAIIVFLVGKMLNTGIFNLIFMHVSEFFPTTLRTTAVGMSSSCARIGASFGAMIFQITLYHDSIAFVIVIGCCLLTGVLVFCLPETYRKKMPTSIEEIKQ 1745
            E+ LDE+GG + +      ++S  +  LP  F +++F  + V P   HCALP        +  +  ++P +  G     SSC QF   +N        +  +PCQ G+ Y  + F S+  TEWDLVCD   LN    + FF+    GA++   +ADRFGRK +L+ +F+   +   A  + +S  +  + + L+G+   G  I+   ++     +++R+ +    +  W+  + +L +  Y +RDWR+     +   +     ++ +PES RW++   + + AQ +L + A +       +K  E   K    +E  K   ++ L + +   L +  L +  VWF  A TYYG+   +   G N +L  F+   +E+PA +  + + ++ GR+     +  L G  +     +          + V   GK  +   F + F++ +E FPT +R   +G +S   R+G S   ++  +     S   ++     +++G + F LPET R ++P +I+++++
Sbjct:    4 EEVLDEVGGFHRFQFVILHILSIPRVILPLNFLLHNF-ISAVPPH--HCALPHLDDRYADHTPQPQLLPHDPDG---ALSSCRQFPELENFNSSGTGSNGSVPCQYGWTYDRRIFNSTTATEWDLVCDSKHLNQALATFFFMGVMMGAVLFGYLADRFGRKPMLLVSFVSSCVLGVAIAFSSSFLMFAICRTLSGVALTGMSITTLVLS---EGIKHRTFSGTILSLGWSVGNMLLALLAYLLRDWRHLMLAVTAPCILAIATWWWVPESARWLLVNGRVEEAQRVLQQCAKMNGKTSKLDK--ETLLKVTINEEPSK--DHSYLDLVKTPKLRKISLCSGIVWFAVAFTYYGISFNISGFGLNAYLTQFIYGAIEVPAKVGTYFLLDRIGRRNGQAWSLILCGMLIGANTAIPSGYSGVRTGVAV--CGKGFSEAAFTIAFLYTAELFPTVIRQCGLGYTSFMGRLGGSLAPLLIMLDDVWSSAPSLVFSIAAVISGCVAFLLPETLRVRLPETIQDVEE 509

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BLAST of slc22a-3 vs. Ensembl Cavefish
Match: slc22a7b.2 (solute carrier family 22 member 7b, tandem duplicate 2 [Source:ZFIN;Acc:ZDB-GENE-030131-9391])

HSP 1 Score: 177.948 bits (450), Expect = 5.378e-48
Identity = 135/511 (26.42%), Postives = 228/511 (44.62%), Query Frame = 3

Query:  282 KWFLLISFMKSLPCVFSMYSFQFTGVKPDSFHCALPP--------NVSRESM----IPKERTGDKWEFSSC-----NQFQSQDNST------IIPCQNGYNYTMKYFTSSIVTEWDLVCDRAILNALATSSFFVMSFFGAIISCSIADRFGRKVVLITAFMCLNLCEFAQTYITSIYVLIVFKLLAGIFQQGCFISGFTMTIELFSLRNRSNACLADTFSWTXXXXXXXXXXXXXRDWRNYFFWTSITMLPFCLVFYHLPESIRWMMAKDQTKNAQILLKTATLYSNPPLPEKTFENYDKYKRKQESEKLPHYNVLHIFRETLLLRYQLINSFVWFTTAMTYYGVQVKVVEIG-NPFLNFFLSSLVEIPANILCFPIANKYGRKITIGLTNFLVGFSLFMGYILWKYLDSPWPAIIVFLVGKMLNTGIFNLIFMHVSEFFPTTLRTTAVGMSSSCARIGASFGAMIFQITLYHDSIAFVIVIGCCLLTGVLVFCLPETYRKKMPTSIEEIK 1742
            K  LL +F+     V       F  V P S HC            N+++E      IP+   G    F SC      QF    NS+      ++ CQNG+ Y    FTSS+ T+WDLVC+   +N    + FF+   FGA    S++  +GRK +L+ +++         T+ +S  +  V +   G    G  I    + +E   +++R    + D+ SWT  +    +  Y+IRDW+      S+ +    + ++ +PES RW++A      A   L+     +N      + +           E    Y+ L + R + + R  L+    WF  A   YG+   V   G N FL  F+   +E+P  +  F + +K GR+  +     LVG SL +   + K  D      ++ ++G+  ++  F  I ++ SE +PT LR   +G +S  AR+GA+   +I  +      ++ VI+    LL  ++ F LPET  + +P +IE+I+
Sbjct:   68 KMLLLNNFVGRFSLVSHFLLNVFIAVIP-SHHCDFSALDVYNVYENLTQEQRLTVSIPQHGDG---TFDSCYMFSEPQFHLLSNSSDTTELPVVRCQNGWVYDNSTFTSSLATQWDLVCENVGMNKAVATIFFIGVMFGAAAFGSLSATYGRKRMLLVSYILGMGFALGSTFSSSFIMFAVLRFFTGFSITGIVIVSTILNVEWVDIKHRKMVGMIDSISWTSGTMCFSLIAYWIRDWKWLTVAVSLPIAASIISWWWIPESARWLIANGNVDKAHYYLQKCADMNNRKEIMSSIKPETLSSIVVTEEGNRKYSYLDLVRTSKIRRLALLTGITWFCVATVAYGIVFNVGSFGLNLFLTQFVYGAIEVPTKVGTFFLLDKIGRRAIVVGGQLLVGLSLLINIFIPK--DQTVVRTVIAVLGRGCSSASFMTIVLYSSELYPTVLRQNGMGYNSFLARLGAAMAPLILLLDEVWGYLSQVILCSVALLAALVAFQLPETRHRCLPETIEDIE 572

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BLAST of slc22a-3 vs. Ensembl Cavefish
Match: slc22a5 (solute carrier family 22 member 4-like [Source:NCBI gene;Acc:103026458])

HSP 1 Score: 176.407 bits (446), Expect = 1.253e-47
Identity = 142/533 (26.64%), Postives = 252/533 (47.28%), Query Frame = 3

Query:  231 DPEKCLDELGGKNIWILKWFLLISFMKSLPCVFSMYSFQFTGVKPDSFHC-ALPPNVSRE---SMIPKERTGDKWEFSSCNQFQ--------------SQDNSTIIP---CQNGYNYTMKYFTSSIVTEWDLVCDRAILNALATSSFFVMSFFGAIISCSIADRFGRKVVLITAFMCLNLCEFAQTYITSIYVLIVFKLLAGIFQQGCFISGFTMTIELFSLRNRSN-ACLADTFSWTXXXXXXXXXXXXXRDWRNYFFWTSITMLPFCLVFYHLPESIRWMMAKDQTKNAQILLKTATLYSNPPLPEKTFENYDKYKRKQESEKLP----HYNVLHIFRETLLLRYQLINSFVWFTTAMTYYGVQVKVVE-IGNPFLNFFLSSLVEIPANILCFPIANKYGRK-ITIGLTNFLVGFSLFMGYILWKYLDSPWPAIIVFLVGKMLNTGIFNLIFMHVSEFFPTTLRTTAVGMSSSCARIGASFGAMIFQITLYHDSIAFVIVIGCCLLTGVLVFCLPETYRKKMPTSIEEIKQ 1745
            D E+    LG K  + L  FLL++ +  +   F  +   F G  P S HC  L  N+S E   + IP E    K E S C ++               S  N T I    C  G+ Y+ + + S+IV+EWDLVC+R      A+S+ ++    G+++S  ++DRFGRK VL  +    ++  FAQ++  S  V  +     G FQ   +I+ F +  E+ S   R     L     +     +L    + IRDWR      S+  + +  +++ +PES RW++++ + K A+ ++K A   +    P+  F       R  E  K+P     Y+++ + + + +     +   +W    + Y+G+ +     IG+PFLN FLS++ E+PA I+   +     R+ +  G  +   GF L +  I  +       A+ + + GK   T  F +++++ +E +PT LR   +GM SS ARIG+     I  +  Y   + ++++    + + +    LPET+ K +P + E++++
Sbjct:    3 DYEEDTAFLGQKGPFFLIIFLLLNAIY-ISTGFHSFYIVFAGASP-SHHCQVLDGNLSEEWIKASIPTEEINGKLEQSKCWRYSLGAIQHFAAEGYNSSSVNFTDIARERCVEGWKYSTEVYHSTIVSEWDLVCEREWRVPFASSTIYMGYLLGSLVSGQLSDRFGRKKVLFASLALESVIIFAQSFSQSWLVFCILYFFVGAFQISLYITAFVLGTEVLSTSLRVLFTTLGAFLHYCVGYMVLPWIAFVIRDWRTLLRVLSVLTVVYIPLWWFIPESPRWLISQGRVKEAEAIIKDAAKKNKVSAPDIIF-------RPLEGNKIPAPARKYSLIDVVKTSNIRFTTFMCLLLWMAINIGYFGLSLNTSNLIGDPFLNCFLSAVAEVPAYIIATLLLKSCPRRPLLSGFLSIGGGFLLLIQLIPERLHTL---AVALEMAGKFGFTMSFTVVYIYTAEIYPTVLRNLGMGMCSSAARIGSITAPYIIFLGTYSKYLPYILMGSLTIGSSIANMFLPETFGKVLPETCEQMQR 523

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BLAST of slc22a-3 vs. Ensembl Cavefish
Match: slc22a7a (solute carrier family 22 member 7a [Source:ZFIN;Acc:ZDB-GENE-050506-52])

HSP 1 Score: 175.252 bits (443), Expect = 2.156e-47
Identity = 136/531 (25.61%), Postives = 245/531 (46.14%), Query Frame = 3

Query:  237 EKCLDELGGKNIWILKWFLLISFMKS-LPCVFSMYSFQFTGVKPDSFHCALP-------PNVSRESMIPKERTGDKWEFSSCNQFQSQDN--------STIIPCQNGYNYTMKYFTSSIVTEWDLVCDRAILNALATSSFFVMSFFGAIISCSIADRFGRKVVLITAFMCLNLCEFAQTYITSIYVLIVFKLLAGIFQQGCFISGFTMTIELFSLRNRSNACLADTFSWTXXXXXXXXXXXXXRDWRNYFFWTSITMLPFCLVFYHLPESIRWMMAKDQTKNAQILLKTATLYSNPPLPEKTFENYDKYKRKQESEKLPH----YNVLHIFRETLLLRYQLINSFVWFTTAMTYYGVQVKVVEIG-NPFLNFFLSSLVEIPANILCFPIANKYGRKITIGLTNFLVGFS-------LFMGYILWKYLDSPWPAIIVFLVGKMLNTGIFNLIFMHVSEFFPTTLRTTAVGMSSSCARIGASFGAMIFQITLYHDSIAFVIVIGCCLLTGVLVFCLPETYRKKMPTSIEEIKQ 1745
            E+ LDE+GG + +      ++S  +  LP  F +++F  + V P   HCALP        +  +  ++P +  G     SSC QF   +N        +  +PCQ G+ Y  + F S+  TEWDLVCD   LN    + FF+    GA++   +ADRFGRK +L+ +F+   +   A  + +S  +  + + L+G+   G  I+   ++IE   +++R+ +    +  W+  + +L +  Y +RDWR+     +   +     ++ +PES RW++   + + AQ +L+                N    K  +E   L H    ++ L + +   L +  L +  VWF  A TYYG+   +   G N +L  F+   +E+PA +  + + ++ GR+     +  L  F        +F+GY   +          V + GK  +   F + F++ +E FPTT+     G+ S   R+G S   ++  +    D I            G + F LPET R ++P +I+++++
Sbjct:    4 EEVLDEVGGFHRFQFVILHILSIPRVILPLNFLLHNF-ISAVPPH--HCALPHLDDRYADHTPQPQLLPHDPDG---ALSSCRQFPELENFNSSGTGSNGSVPCQYGWTYDRRIFNSTTATEWDLVCDSKHLNQALATFFFMGVMMGAVLFGYLADRFGRKPMLLVSFVSSCVLGVAIAFSSSFLMFAICRTLSGVALTGMSITTLALSIEWTGIKHRTFSGTILSLGWSVGNMLLALLAYLLRDWRHLMLAVTAPCILAIATWWWVPESARWLLVNGRVEEAQRVLQQCAKM-----------NGKTSKLDKEVAGLTHPSKDHSYLDLVKTPKLRKISLCSGIVWFAVAFTYYGISFNISGFGLNAYLTQFIYGAIEVPAKVGTYFLLDRIGRRNGQAWSLILSFFHAVCMCVCVFVGYSGVR--------TGVAVCGKGFSEAAFTIAFLYTAELFPTTVWFW--GLHSFMGRLGGSLAPLLIML----DGI------------GCVAFLLPETLRVRLPETIQDVEE 491

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BLAST of slc22a-3 vs. Ensembl Sea Lamprey
Match: oct2 (organic cation transporter 2 [Source:ZFIN;Acc:ZDB-GENE-080204-92])

HSP 1 Score: 128.642 bits (322), Expect = 1.123e-31
Identity = 94/426 (22.07%), Postives = 198/426 (46.48%), Query Frame = 3

Query:  480 NSTIIPCQNGYNYTMKYFTSSIVTEWDLVCDRAILNALATSSFFVMSFFGAIISCSIADRFGRKVVLITAFMCLNLCEFAQTYITSIYVLIVFKLLAGIFQQGCFISGFTMTIELFSLRNRSNACLADTFSWTXXXXXXXXXXXXXRDWRNYFFWTSITMLPFCLVFYH--LPESIRWMMAKDQTKNAQILLKTATLYSNPPLPEKTFENYDKYKRKQESEKLPHYNVLHIFRETLLLRYQLINSFVWFTTAMTYYGVQVKVVEIGNP-FLNFFLSSLVEIPANILCFPIANKYGRKITIGLTNFLVGFSLFMGYILWKYLDSPWPAIIVFLVGKMLNTGIFNLIFMHVSEFFPTTLRTTAVGMSSSCARIGASFGA-MIFQITLYHDSIAFVIVIGCCLLTGVLVFCLPETYRKKMPTSIEEIKQ 1745
            +  +I C +G+ +  +    ++V+E+DLVC+ A L  L+ +   V    GAI+   ++DR+GR+  L+ + +   +      +  +    +  + L GIF  G + + F    E      R    +     ++F   +L    Y++R WR  +   ++T+    L  Y+  LPES RW++++++ + A  +LK     +   L +   +N+++  R  E    P  ++  + R   + +Y ++    WF   + Y G+ +    IG+  +L F +  L EIP  ++   + ++ GR++ + +   L G +     ++    D  W  I +  +G++  T  + ++ +  +E +PT LR  A+   SS + IG      +++++      +  VI     ++ G ++  LPET    +P + E+ + 
Sbjct:  121 SGRLIACDHGWEFDTEKTGLTLVSEFDLVCENAWLLDLSQALLNVGLLVGAILMGYVSDRYGRRWSLMVSIVMQTIFGVLVAFAPNYAAFVCMRTLQGIFNMGSWTTVFVTATEFVGSGQRRVVHMVLQMFFSFGVIMLSGIAYYLRTWR--YLQLALTLPNVVLFSYYWLLPESPRWLISQNRKEQAFGVLKKIASVNGRELSDNIRKNFEEVTRADEKAGNP--SIADLMRSAKIRKYTVVLMIYWFVVGVVYQGLAMSTGNIGDDVYLAFLMGGLAEIPGALMVIALIDRVGRRLPMCVAPGLSGLACLATALVPH--DIGWLNITLVTLGRLGLTMAYEMVTLVNNELYPTHLRNMAMSTCSSLSGIGGIVAPFVLYRLYTIWRHLPMVIFGTLAIIGGFVILLLPETNGLPLPETTEDAEN 540

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BLAST of slc22a-3 vs. Ensembl Sea Lamprey
Match: SLC22A7 (solute carrier family 22 member 7 [Source:HGNC Symbol;Acc:HGNC:10971])

HSP 1 Score: 95.9005 bits (237), Expect = 6.517e-22
Identity = 52/219 (23.74%), Postives = 110/219 (50.23%), Query Frame = 3

Query:  417 PKERTGDKWEFSSCNQFQS----------QDNSTIIPCQNGYNYTMKYFTSSIVTEWDLVCDRAILNALATSSFFVMSFFGAIISCSIADRFGRKVVLITAFMCLNLCEFAQTYITSIYVLIVFKLLAGIFQQGCFISGFTMTIELFSLRNRSNACLADTFSWTXXXXXXXXXXXXXRDWRNYFFWTSITMLPFC-LVFYHLPESIRWMMAKDQTKNAQ 1040
            P  R  D+   S+C+  ++          +++S  +PC +G+ Y  + FT ++VT+WDLVC+   LN L+ + F      G+++   ++DR+GR+  L+ +++   +   A  +  S       + L G+   G  ++  ++++E     +R+ A  +  F+W+  +  L +  Y +R W+        + + FC L ++ +PES RW++ + + + A 
Sbjct:   74 PPWRDDDEEGLSACSLREAAGTNASESPLRNSSEAVPCPSGWEYDRRQFTETVVTQWDLVCEHKALNHLSLTLFMAGVMLGSLVFGYLSDRYGRRNALLGSYVLNAVTGTAAAWAPSFSSFTAMRFLLGVSLSGIIVNTLSLSVEWLDQGHRTFAGTSGGFAWSTGNMALGLLAYLLRGWQQLQL-VVTSPIYFCILTWWFIPESPRWLLVRGRAREAH 291

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BLAST of slc22a-3 vs. Ensembl Sea Lamprey
Match: si:dkey-190l8.2 (si:dkey-190l8.2 [Source:ZFIN;Acc:ZDB-GENE-030131-9103])

HSP 1 Score: 94.3597 bits (233), Expect = 6.431e-21
Identity = 93/391 (23.79%), Postives = 170/391 (43.48%), Query Frame = 3

Query:  600 SSFFVMSFFGAIISCSIADRFGRKVVLITAFMCLNLCEFAQTYITSIYVLIVFKLLAGIFQQGCFISGFTMTIELFSLRNRSNACLADTFSWTXXXXXXXXXXXXXRDWRNYFFWTSITMLPFCLVFYHLPESIRWMMAKDQTKNAQILLKTATLYSNPPLPEKTFENYDKYKRKQESEKLPHYNVLHIFRETLLLRYQLINSFVWFTTAMTYYGVQVKVVEIG-NPFLNFFLSSLVEIPANILCFPIANKYGRKITIGLTNFLVGFSLFMGYILWKYLDSPWPAIIVFLVGKMLNTGIFNLIFMHVSEFFPTTL-------RTTAVGMSSSCARIGASFGAMIFQITLYHDSIAFVIVIGC-CLLTGVLVFCLPETYRKKMPTSIEEIKQ 1745
            ++F V    G+I     +DR+GR+ VL+         EF   ++ +    ++ +LL G    G  +  F++ +E      R+   +    +++     L       ++W      T +  L   L+F+ LPES RW+  K +T  A+ LL+ A++ +      +      +   K  +       +L  FR   L +  LI S++    +MTYYG+ + V + G +  +  FLS L EIP  +L  P+  + GR+    +   + G +  +   L   L +    + + L+GK+       +  ++  E FPT +       R  A+G  + C  +G+    ++ +  L    ++ + V GC  L    L   LPET R   P S+EE ++
Sbjct:   23 TTFMVGLLVGSIAMGIASDRYGRRPVLLGCVASQGAAEFVIAFLPNFPTYLLGRLLTGTTASGIMLCSFSLGVEWCGPALRAWPPIILALAFSVGMMALAGVAKISQNWPQLHLATGVPQLMVLLLFWSLPESPRWLFLKKRTTEARNLLRQASIINR---RSEVSWTPLRLTSKLSTRGANESTLLITFRNRTLRKRLLIMSYICAAVSMTYYGLCLSVGDFGLDIHMAQFLSGLAEIP-QLLLPPLMRRVGRRSLCIVFLSVAGATCLLCLPLQPNLAN--VVVALALLGKLCAQVTACVATLYRIELFPTNVRPRCHGHRQNALGAVAMCGSVGSLLAPLVNRAALVLG-VSALSVHGCLPLAGAALALLLPETRRAPFPDSVEECER 406

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BLAST of slc22a-3 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000007122.1 (pep scaffold:Pmarinus_7.0:GL476962:153150:164773:-1 gene:ENSPMAG00000006444.1 transcript:ENSPMAT00000007122.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 81.2629 bits (199), Expect = 1.901e-17
Identity = 52/203 (25.62%), Postives = 89/203 (43.84%), Query Frame = 3

Query:  360 KPDSFHCALPPNVSRESMIPKERTGDKWEFSSCNQFQSQDNSTIIPCQNGYNYTMKYFTSSIVTEWDLVCDRAILNALATSSFFVMSFFGAIISCSIADRFGRKVVLITAFMCLNLCEFAQTYITSIYVLIVFKLLAGIFQQGCFISGFTMTIELFSLRNRSNACLADTFSWTXXXXXXXXXXXXXRDWRNYFFWTSITMLPF 968
             P   H  +P   +      +    +  E   C      + S   PC  G++Y    FTS++VTEWDLVC R+ LN + +S F +    GA +  ++AD++GRK V++ +            +  +  +  + + + G+   G  ++ F +  E   +  R  A +A   ++     +L    YFIRDWR      SI  + F
Sbjct:   51 DPPGGHAPVPSATTAPPTAGESAAANGTERPRCGS--RLNESGWQPCATGWDYDRSVFTSTVVTEWDLVCTRSYLNNVGSSIFMLGLMVGAPVLGTMADKYGRKSVILVSMAIQTAFGLGAAFAPNFVMYALARFMVGVAISGVIMNAFVLATEWTGIGERMLAGIATQQAFGVGYMLLAPVAYFIRDWRQLQLAISIPEILF 251

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BLAST of slc22a-3 vs. Ensembl Sea Lamprey
Match: slc22a6l (solute carrier family 22 member 6, like [Source:NCBI gene;Acc:404609])

HSP 1 Score: 80.1073 bits (196), Expect = 1.067e-16
Identity = 72/314 (22.93%), Postives = 140/314 (44.59%), Query Frame = 3

Query:  816 IELFSLRNRSNACLADTFSWTXXXXXXXXXXXXXRDWRNYFFWTSITMLPFCLVFYHLPESIRWMMAKDQTKNAQILLKTATLYSNPPLPEKTFENYDKYKRKQ-ESEKLPH--YNVLHIFRETLLLRYQLINSFVWFTTAMTYYGVQVKVVE--IGNPFLNFFLSSLVEIPANILCFPIANKYGRKITIGLTNFLVGFSLFMGYILWKYLDSPWPAIIVFLVGKMLNTGIFNLIFMHVSEFFPTTLRTTAVGMSSSCARIGASFGAMIFQITLYHDSIAFVIVIGCCLLTGVLVFCLPETYRKKMPTSIEEIK 1742
            +E  ++++R+   +    ++T    +L+   Y+IRDWR+     S     F L  +  PES RW++ +   + A   LK   + +          +  +Y RK+ E +  P   Y + ++     L R  L+ S VW      +Y   V +V     + FL   +   ++ PA ++   + +  GR+ T   +  +   + F   +L    +S      + ++GK   +  FN  +++  E FPT +R + +G+ S+ AR+G     ++        ++   +     L+ G LV+ LPET  + +P +IEE+ 
Sbjct:    1 VEWIAMKDRTLYGMLSGVAYTTGQLVLVALAYYIRDWRHLQHSISAAFYVFFLCSWCTPESARWLVMRGHYERALHGLKRVAVINGRKREAAQLTSPLQYLRKELEEDTGPRRFYTMFNLLTIPALRRRTLVMSLVWCDDVFCWYAGFVVIVTRTCAHTFLLQVIYGAIDYPAKVVGLVVLSLLGRRATQAGSLAVASIASFC--LLAIPAESGTARTCLAVLGKGALSCSFNCAYLYTGEIFPTVIRQSGLGLCSTMARVGGMLAPLVIMAGESLPALPLSMYGSASLVAGSLVYFLPETLNRPLPETIEELS 312

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BLAST of slc22a-3 vs. Ensembl Yeast
Match: CIN10 (Putative transporter; member of the sugar porter family; non-essential gene; overexpression results in elevated colony sectoring, an indicator of chromosomal instability [Source:SGD;Acc:S000002795])

HSP 1 Score: 48.9062 bits (115), Expect = 1.835e-6
Identity = 52/214 (24.30%), Postives = 89/214 (41.59%), Query Frame = 3

Query:  552 EWDLVCDRAILNALATSSFFVMSFFGAIISCSIADRFGRKVVLITAFMCLNLCEFAQTYITSIYVLIVFKLLAGI---FQQGCF-----------ISGFTMTIELFSLRNRSNACLADTFSWTXXXXXXXXXXXXXRDWRNYFFWTSITMLPFCLVFYHLPESIRWMMAKDQ---TKNA-QILLKTATLYSNPPLPEKTFENYDKYKRKQESEK 1139
            +  LV    +   L TSS  V SFFG+I++  +ADR+GR++ L        L         ++  LI  +LL GI       C            I GF +T+ +          +A T     S  I  +       WR  F  ++I  + F  +   +PES RW ++K     T+++ ++L  TA+ Y      ++     DK +  +++ +
Sbjct:   71 DLSLVVLTDVQKELITSSTSVGSFFGSILAFPLADRYGRRITLAICCSIFILAAIGMAIARTLTFLICGRLLVGIAVGVSAQCVPLFLSEISPSRIRGFMLTLNI----------IAITGGQLVSYVIASLMKEIDNSWRYLFALSAIPAILFLSILDFIPESPRWSISKGDILYTRDSLRMLYPTASTYHVNSKIKQLIIELDKLRLYEDASE 274

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BLAST of slc22a-3 vs. Ensembl Nematostella
Match: EDO47316 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RMR6])

HSP 1 Score: 178.333 bits (451), Expect = 3.258e-49
Identity = 128/437 (29.29%), Postives = 218/437 (49.89%), Query Frame = 3

Query:  450 SSCN---QFQSQDNSTIIPC---QNGYNYTMKYFTSSIVTEWDLVCDRAILNALATSSFFVMSFFGAIISCSIADRFGRKVVLITAFMCLNLCEFAQTYITSIYVLIVFKLLAGIFQQGCFISGFTMTIELFSLRNRSNACLADTFSWTXXXXXXXXXXXXXRDWRNYFFWTSITMLPFCLVFYHLPESIRWMMAKDQTKNAQILLKTATLYSNPPLPEKTFENYDKYKRKQESEKLPHYNVLHIFRETLLLRYQLINSFVWFTTAMTYYGVQVKVVEIGNP-FLNFFLSSLVEIPANILCFPIANKYGRKITIGLTNFLVGFSLFMGYILWKYLDSPW---PAIIVFLVGKMLNTGIFNLIFMHVSEFFPTTLRTTAVGMSSSCARIGASFGAMIFQITLYHDSIAFVIVIGCCLLTGVLVFCLPETYRKKMPTSI 1730
            SSCN    F+  D +    C   ++ + + +     SIVTEWDLVC +++   +A S  F++  FGA+    I+D+FGRK+V+    +  +LC  A  +    +V  +F+ L G    G  I GF + +E   +R+RS       + W  + F+L +  Y I  WR     TS   L F + ++  P+S+RW + K +  +A+ +L            ++ FE  +++    E E+L   ++  +F    +    L++ + W  + + YYG+ +    IG   +LNFFLS+L E     +  P+ +++GRK TI  + ++   +  +  +L +Y D        I   ++ K   T  F+ ++++ SE FPT +R TA+G S+S ARIG SF A   Q    H  + F I+    L+ G+L   LPET  K +P ++
Sbjct:   55 SSCNFTGTFKPGDANYEKRCMMARDQWEFAIDAGFDSIVTEWDLVCSKSMYATIANSITFILWIFGAMAGSIISDKFGRKIVVFPCVIFASLCGLASAFANKYWVFALFRALLGAGIGGYSICGFVLVMEYIGIRHRSIVGFCVWYPWILALFMLALLGYLIPSWRTLSIITSAPGLLFFVFWWFTPDSLRWYLVKGKFDDAKKVLVDVAKGCGNNYTKQDFEFEEEHTFNIEHERLG--DIRDLFHSRSMAHRTLVSWYCWLVSGLVYYGISLSSTTIGGDMYLNFFLSALFEGIGMAIGIPLLDRFGRKKTIVASMYVAALAAIVAALLSQYDDGTMLVGKIISAMVIAKFFVTIAFDGVYVYSSELFPTVVRNTAMGTSTSAARIG-SFAAPFTQKV--HPMMPFGIMALNALICGILCMTLPETKDKPLPDTV 486

[Close]

BLAST of slc22a-3 vs. Ensembl Nematostella
Match: EDO27829 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T865])

HSP 1 Score: 179.874 bits (455), Expect = 5.883e-49
Identity = 123/444 (27.70%), Postives = 219/444 (49.32%), Query Frame = 3

Query:  450 SSCN---QFQSQDNSTIIPC---QNGYNYTMKYFTSSIVTEWDLVCDRAILNALATSSFFVMSFFGAIISCSIADRFGRKVVLITAFMCLNLCEFAQTYITSIYVLIVFKLLAGIFQQGCFISGFTMTIELFSLRNRSNACLADTFSWTXXXXXXXXXXXXXRDWRNYFFWTSITMLPFCLVFYHLPESIRWMMAKDQTKNAQILLKTATLYSNPPLPEKTFENYDKYKRKQESEKLPHYNVLHIFRETLLLRYQLINSFVWFTTAMTYYGVQVKVVEIGNP-FLNFFLSSLVEIPANILCFPIANKYGRKITIGLTNFLVGFSLFMGYILWKYLDSPWPAII-----VFLVGKMLNTGIFNLIFMHVSEFFPTTLRTTAVGMSSSCARIGASFGAMIFQITLYHDSIAFVIVIGCCLLTGVLVFCLPETYRKKMPTSIEEIKQ 1745
            SSCN    F+  D +    C   ++ + + +     SIVTEWDLVC +++   +A S  F++  FGA+    I D+FGRK+V+    +  +LC  A  +    +V  +F+ L G    G  I GF + +E   +R+RS       + W  + F+L +  Y I  WR     TS   L F + ++  P+S+RW + K +  +A+ +L            ++ FE  +++    E E+L   ++  +F    +    L++ + W  + + YYG+ +    IG   +LNFFLS+L E     +  P+ +++GRK TI  + ++   +  +  +L +Y D     ++       ++ K   T  F+ ++++ SE FPT +R TA+G S+S ARIG+            H  + F I+    L+ G+L   LPET  K +P ++++ ++
Sbjct:   55 SSCNFTGTFKPGDANYEKRCLMARDQWEFAIDAGFDSIVTEWDLVCSKSMYATIANSITFILWIFGAMAGSIIGDKFGRKIVVFPCVIFASLCGLASAFANKYWVFALFRALLGAGIGGYSICGFVLVMEYIGIRHRSIVGFCVWYPWILALFMLALLGYLIPSWRTLSIITSAPGLLFFVFWWFTPDSLRWYLVKGKFDDAKKVLVDVAKGCGNNYTKQDFEFEEEHTFNIEHERLG--DIRDLFHSRSMAHRTLVSWYCWLVSGLVYYGISLSSTTIGGDMYLNFFLSALFEGIGMAIGIPLLDRFGRKKTIVASMYVAALAAIVAALLSQYDDGSQAMLVGKIISAMVIAKFFVTIAFDGVYVYSSELFPTVVRNTAMGTSTSAARIGSFAAPFTVYSQKVHPMMPFGIMALNALICGILCMTLPETKDKPLPDTVKQTEE 496

[Close]

BLAST of slc22a-3 vs. Ensembl Nematostella
Match: EDO36597 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SI67])

HSP 1 Score: 174.866 bits (442), Expect = 5.567e-48
Identity = 129/437 (29.52%), Postives = 215/437 (49.20%), Query Frame = 3

Query:  450 SSCN---QFQSQDNSTIIPC---QNGYNYTMKYFTSSIVTEWDLVCDRAILNALATSSFFVMSFFGAIISCSIADRFGRKVVLITAFMCLNLCEFAQTYITSIYVLIVFKLLAGIFQQGCFISGFTMTIELFSLRNRSNACLADTFSWTXXXXXXXXXXXXXRDWRNYFFWTSITMLPFCLVFYHLPESIRWMMAKDQTKNAQILLKTATLYSNPPLPEKTFENYDKYKRKQESEKLPHYNVLHIFRETLLLRYQLINSFVWFTTAMTYYGVQVKVVEIGNP-FLNFFLSSLVEIPANILCFPIANKYGRKITIGLTNFLVGFSLFMGYILWKYLDSPW---PAIIVFLVGKMLNTGIFNLIFMHVSEFFPTTLRTTAVGMSSSCARIGASFGAMIFQITLYHDSIAFVIVIGCCLLTGVLVFCLPETYRKKMPTSI 1730
            SSCN    F+  D +    C   ++ + + +     SIVTEWDLVC +++   +A S  F++  FGA+    I D+FGRK+V+    +  +LC  A  +    +V  +F+ L G    G  I  F + +E   +R+RS       + W  + F+L +  Y I  WR     TS   L F  VF+  P+S+RW + K +  +A+ +L            ++ FE  +++    E E+L   ++  +F    +    L++ + W  + + YYG+ +    IG   +LNFFLS+L E     +  P+ +++GRK TI  +  +   +  +  +L +Y D        I   ++ K   T  F+ ++++ SE FPT +R TA+G S+S ARIG SF A   Q    H  + F I+    L+ G+L   LPET  K +P ++
Sbjct:   55 SSCNFTGTFKPGDANYEKRCLMARDQWEFAIDAGFDSIVTEWDLVCSKSMYATIANSITFILWIFGAMAGSIIGDKFGRKIVVFPCVIFASLCGLASAFANKYWVFALFRALLGAGIGGYSICSFVLVMEYIGIRHRSIVGFCVFYPWILALFMLALLGYLIPSWRTLSIITSAPGLLF-FVFWFTPDSLRWYLVKGKFDDAKKVLVDVAKGCGNNYTKQDFEFEEEHTFNIEHERLG--DIRDLFHSRSMAHRTLVSWYCWLVSGLVYYGISLSSTTIGGDMYLNFFLSALFEGIGMAIGIPLLDRFGRKKTIAASMCVAALAAIVAALLSQYDDGTMLVGKIISAMVIAKFFVTIAFDGVYVYSSELFPTVVRNTAMGTSTSAARIG-SFAAPFTQKV--HPMMPFGIMALNALICGILCMTLPETKDKPLPDTV 485

[Close]

BLAST of slc22a-3 vs. Ensembl Nematostella
Match: EDO46087 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RR13])

HSP 1 Score: 160.229 bits (404), Expect = 1.025e-42
Identity = 115/413 (27.85%), Postives = 197/413 (47.70%), Query Frame = 3

Query:  513 NYTMKYFTSSIVTEWDLVCDRAILNALATSSFFVMSFFGAIISCSIADRFGRKVVLITAFMCLNLCEFAQTYITSIYVLIVFKLLAGIFQQGCFISGFTMTIELFSLRNRSNACLADTFSWTXXXXXXXXXXXXXRDWRNYFFWTSITMLPFCLVFYHLPESIRWMMAKDQTKNAQILLKTATLYSNPPLPEKTFE-NYDKYKRKQESEKLPHYNVLHIFRETLLLRYQLINSFVWFTTAMTYYGVQVKVVEI-GNPFLNFFLSSLVEIPANILCFPIANKYGRKITIGLTNFLVGFSLFMGYILWKYLDSPWP---AIIVFLVGKMLNTGIFNLIFMHVSEFFPTTLRTTAVGMSSSCARIGASFGAMIFQITLYHDSIAFVIVIGCCLLTGVLVFCLPETYRKKMPTSIEE 1736
             YT KY  +SI+TEWDLVC+ A    L  S     +  GA++  ++AD++GR+ V  T    L +  FA ++  +  +    + L G    G  +S F +  EL     R  A +     +T    IL +  Y I+DWR      S+    F L F ++PES RW+M + +   A+ +L    L +   +P+   + N+  +   +       Y    +F    +++   +  F+WF   + YYG+ +    + G+ ++NFFL SL+E PA + C    N  GR+ T+     L G +  M  +  +   SP     A +  ++GK   T  F LI+++ +E FPT +R   +G+ S  +RIG      +  +  Y   +  VI   C  + G+L   LPET+++ +P ++++
Sbjct:   69 QYTSKY--TSIITEWDLVCENAYKADLVQSLLMSGTLLGALMFGALADKYGRRRVWHTTLTGLVVFGFASSFAPTFKIYATLRFLTGFCIGGEILSAFVLATELVGPSYRGFAGIMAQCFFTLGLLILPMVAYLIQDWRTLSVVLSLPASVFILFFRYVPESARWLMIRGRVSEAENILLDIALKNGIAVPKSLLQVNHPFFVGSR-------YGFFDLFCTRKIVKQTFVLIFIWFVNTLVYYGLSLNTKHLAGDIYMNFFLCSLMEFPAYLTCLFFVNWAGRRKTLFNYMVLAGLAC-MACMFVQPESSPADRTLATVFAMIGKFGITASFALIYIYSAEIFPTVVRNVGLGVCSMSSRIGGICAPFVVFLGTYMRPLPMVIFGMCAFMAGLLSLMLPETHKRPLPETMDD 471

[Close]

BLAST of slc22a-3 vs. Ensembl Nematostella
Match: EDO46581 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RPJ7])

HSP 1 Score: 157.532 bits (397), Expect = 1.260e-42
Identity = 113/400 (28.25%), Postives = 196/400 (49.00%), Query Frame = 3

Query:  552 EWDLVCDRAILN-ALATSSFFVMSFFGAIISCSIADRFGRKVVLITAFMCLNLCEFAQTYITSIYVLIVFKLLAGIFQQGCFISGFTMTIELFSLRNRSNA-CLADTFSWTXXXXXXXXXXXXXRDWRNYFFWTSITMLPFCLVFYHLPESIRWMMAKDQTKNAQILLKTATLYSNPPLPEKTFENYDKYKRKQESEKLPH-YNVLHIFRETLLLRYQLINSFVWFTTAMTYYGVQVKVVEI-GNPFLNFFLSSLVEIPANILCFPIANKYGRKITIGLTNFLVGFSLFMGYILWKYLDSPWPAIIV--FLVGKMLNTGIFNLIFMHVSEFFPTTLRTTAVGMSSSCARIGASFGAMIFQITLYHDSIAFVIVIGCCLLT-GVLVFCLPETYRKKMPTSI 1730
            +WD++CD +     L  + F+     GA +   I+DRFGR+V L++  +   +    Q +  + Y+ +  ++  GI   G  I+ F +  E+     R+ A CLA   S+     +  +  Y + +W+N+    +I  + F L ++ +PES RW+ A+ + K+A+++L+     +     E   +      R+  SEK    Y++ H+F    L +  +I  + WF T+  YYG+      + G+ ++NF  S LVEIPA IL   + ++ GRK        L+ + +  G  L   L     A+++   L+GK   +  +  I++H +E +PT +RT  VG +S CAR+GA     +   T     IA  I+ G   +T G++ F LPET    +P  I
Sbjct:    1 QWDIICDDSKKYIPLTKTIFYAGKLLGAYLFGWISDRFGRRVTLLSTMLIQFISSLIQCFSVNFYMYVALRVPLGICSGGTLIAAFALMAEMVGPNRRNWANCLAQG-SYGVGIALEALIAYLLPEWKNFSLAVTIPNVLFVLYWWFVPESPRWLAARGRIKDAEVILRKIAKTNGHEYQEGALQEIKS--REMVSEKPEKTYHLWHLFSTIYLAKVTIIEGWSWFVTSGVYYGLSFNSGNLSGDFYVNFAASGLVEIPAYILASVLVDRIGRK------KPLIAYYIIGGLALLSLLPIQALALVMTFALIGKFTISAAYYQIYIHSAELYPTVIRTIGVGFASLCARVGAMGAPYVADST---PLIAPAIIFGGLSMTAGMVTFFLPETRGMPLPDHI 388

[Close]

BLAST of slc22a-3 vs. Ensembl Medaka
Match: slc22a7a (solute carrier family 22 member 7 [Source:NCBI gene;Acc:101169334])

HSP 1 Score: 186.037 bits (471), Expect = 3.970e-51
Identity = 148/527 (28.08%), Postives = 253/527 (48.01%), Query Frame = 3

Query:  237 EKCLDELGGKNIWILKWFLLISFM----KSLPCVFSMYSFQFTGVKPDSFHCALPPNVSRES----------MIPKERTGDKWEFSSCNQFQ-------SQDNSTIIPCQNGYNYTMKYFTSSIVTEWDLVCDRAILNALATSSFFVMSFFGAIISCSIADRFGRKVVLITAFMCLNLCEFAQTYITSIYVLIVFKLLAGIFQQGCFISGFTMTIELFSLRNRSNACLADTFSWTXXXXXXXXXXXXXRDWRNYFFWTSITMLPFCLVFYHLPESIRWMMAKDQTKNA-QILLKTATLYSNPPLPEK-TFENYDKYKRKQESEKLPHYNVLHIFRETLLLRYQLINSFVWFTTAMTYYGVQVKVVEIG-NPFLNFFLSSLVEIPANILCFPIANKYGRKITIGLTNFLVGFSLFMGYILWKYLDSPWPAIIVFLVGKMLNTGIFNLIFMHVSEFFPTTLRTTAVGMSSSCARIGASFGAMIFQITLYHDSIAFVIVIGCCLLTGVLVFCLPETYRKKMPTSIEEIKQ 1745
            E+ LD++GG + +    FLL+S +      LP  F +++F  +   P       P + +  S           IP+E  G    FSSC  F+       S+ N T+ PCQ+G+ +     +S+  +EWDLVC+   LN    + FF+   FGAI+   ++D+FGRK +++ AF+   L      + TS  +  V + L G+   G  I    + IE   +++R+   +    SW+  + +L +  +FIRDWR+     +  ++   + ++ LPES RW++   +T+ A + L++ A +        K   E   K    + ++K   Y  L + +   L +  L + F WF  A  YYG+  ++   G N +L  F+   VE+PA IL F + +  GR+   G   FL+   + +G      LD      +V +V K  + G F   F++ +E +PT LR   +G +S   RIG+S   M+  +      +  +I  G  + +G LVF LPET    +P +I ++++
Sbjct:    4 EEILDDIGGFSKF---QFLLLSILCLPRAILPLHFLLHNF-ISATPPHRCSLGSPEDRNGSSWETDPGVLALRIPQEEDGS---FSSCRAFELPLSSNLSRANGTV-PCQHGWIFDQTELSSTTSSEWDLVCNEKNLNQALATYFFLGVTFGAIVFGQLSDKFGRKSMILVAFISSTLLGATSAFSTSYVMFAVSRALCGMALSGMSIISVVLGIEWTDIKHRTFTTIITGLSWSVGNMLLALLAFFIRDWRHLTLVVTAPIVLTIISWWWLPESARWLLTHGRTEEAKKYLVQCAKMNGRKEDTAKLDTETLAKITVSEVAKKKHTY--LDLVKTPQLRKITLCSGFFWFAVAFLYYGISFRISGFGVNIYLTQFIYGAVEVPAKILAFFLVDWIGRR--NGQALFLISTGVLIGINTAVPLDYTVVRTVVAVVAKGFSEGAFTTAFLYSAELYPTVLRQCGIGYTSCLCRIGSSLAPMVMLLEDVWLLLPPLIFAGTGIFSGSLVFLLPETLNAHLPENILDVEE 518

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BLAST of slc22a-3 vs. Ensembl Medaka
Match: slc22a7b.3 (solute carrier family 22 member 7-like [Source:NCBI gene;Acc:101169903])

HSP 1 Score: 182.185 bits (461), Expect = 6.598e-50
Identity = 147/546 (26.92%), Postives = 256/546 (46.89%), Query Frame = 3

Query:  228 MDPEKCLDELGGKNIWILKWFLLISFMK--SLPCVFSMYSFQFTGVKPDSFHCALPP--------NVSRESM----IPKERTGDKWEFSSCNQFQ---------SQDNST---IIPCQNGYNYTMKYFTSSIVTEWDLVCDRAILNALATSSFFVMSFFGAIISCSIADRFGRKVVLITAFMCLNLCEFAQTYITSIYVLIVFKLLAGIFQQGCFISGFTMTIELFSLRNRSNACLADTFSWTXXXXXXXXXXXXXRDWRNYFFWTSITMLPFCLVFYHLPESIRWMMAKDQTKNAQILLK-----TATLYSNPPLPEKTFENYDKYKRKQESEKLPHYNVLHIFRETLLLRYQLINSFVWFTTAMTYYGVQVKVVEIG-NPFLNFFLSSLVEIPANILCFPIANKYGRKITIGLTNFLVGFSLFMGYILWKYLDSPWPAIIVFLVGKMLNTGIFNLIFMHVSEFFPTTLRTTAVGMSSSCARIGASFGAMIFQITLYHDSIAFVIVIGCCLLTGVLVFCLPETYRKKMPTSIEEI-KQWVAHKPI 1766
            M  E  LDE+ G   + +   + I+F+   +LPC F + +F      P + HC +          N+S E      IP ++ G     SSC  F          S  N T    + CQNG+ Y    F S+I +EWDLVCD+   N  + + FF+   FGAI   S++DR+GR+V+L+ +++   +   A  + T+  +  V +   G    G  I    +++E   + +R    + D+FSW+  + +     Y I DWR      S  ++   + +  +PES RW++A  + + AQI LK          S+P L  +T     + K+  ++     Y+ L + R   + +  L    +WF  A  YYG+   +  +G + +L  F+ SL+E+PA    + + +K GR+ T      L+  ++ +G  L    D   P  +V ++GK  ++  F+ + ++ SE +PT LR    G +S   R+G +    I  +    + +  +++    L  G++   L ET  + +P +IE+I +QW   KP+
Sbjct:    1 MKFENVLDEINGFGKFQIM-IIGINFLGRFTLPCHFMLSNF--IAAVP-AHHCDIKSFDNEGIFKNLSWEEKLLVSIPVQQDGTP---SSCQMFVEPQYHLLLLSSPNVTEMLTVSCQNGWVYDNTTFKSTITSEWDLVCDKRDKNKASATIFFIGVMFGAISFGSLSDRYGRRVMLLVSYISALIFAVASAFSTTYEMFAVLRFFTGFCITGIVIVSAVLSVEWVDVNHRKLVGVVDSFSWSVWNCVFPGIAYHITDWRWLILCVSSPLILSIITWRWMPESARWLIANGKFEQAQIHLKKCAKMNGAEESSPILSIETLATIIETKKTDQT-----YSYLDLIRTPKMRKIALSTGILWFCLATAYYGISFNIQGLGLSIYLTQFVYSLIELPAKGTVYYLLDKIGRRPT--QMGALLCAAICLGINLVIPKDLSVPRTVVAVIGKGFSSASFSTVVLYCSELYPTVLRQNGFGYNSFMGRLGVALAPFILLLDEVWEKLPQLVLCLLALTGGLVARTLSETRNRFLPETIEDIEQQWKNKKPL 532

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BLAST of slc22a-3 vs. Ensembl Medaka
Match: slc22a4 (solute carrier family 22 member 4 [Source:NCBI gene;Acc:101163192])

HSP 1 Score: 179.489 bits (454), Expect = 9.107e-49
Identity = 140/505 (27.72%), Postives = 235/505 (46.53%), Query Frame = 3

Query:  315 LPCVFSMYSFQFTGVKPDSFHCALPPNVS-----RESMIPKERTGDKWEFSSCNQFQ-------SQDNSTIIP-------------CQNGYNYTMKYFTSSIVTEWDLVCDRAILNALATSSFFVMSFFGAIISCSIADRFGRKVVLITAFMCLNLCEFAQTYITSIYVLIVFKLLAGIFQQGCFISGFTMTIELFSLRNRSNACLADTFSWTXXXXXXXXXXXX-XRDWRNYFFWTSITMLPFCLVFYHLPESIRWMMAKDQTKNAQILLKTATLYSNPPLPEKTFENYDKYKRKQESEKLPHYNVLHIFRETLLLRYQLINSFVWFTTAMTYYGVQVKVVEI-GNPFLNFFLSSLVEIPANILCFPIANKYGRKITIGLTNFLVGFSLFMGYILWKYLDSPWPAIIVFLVGKMLNTGIFNLIFMHVSEFFPTTLRTTAVGMSSSCARIGASFGAMIFQITLYHDSIAFVIVIGCCLLTG-VLVFCLPETYRKKMPTSIEEIKQ 1745
            LP  F+     F G  P    C +P + S     R   IP E        SSC +         SQ N  IIP             CQ+G+ Y+ + + S+IVTEWDLVCD A    L TS  +V    G ++S  ++DRFGRK +L        +   AQ +  +  +      L G      +   F +  E+ S R R   C    F  +   ++ +  + + +RDWR+     + + L +  +++ L ES RW++++ + + A+ +LK A   +   +PE  F   +        E+    N++ I +   +L   +  + +W    ++YY + +    + GNP+LN FLS++ E+PA I+   +     R I    T FL G  +    ++   +D P  A+++ ++GK   T  F +++   SE FPT +R TA+G  S  ARI       I  +  Y+ ++ + IV+G   L+G V+ F LPET  K +P +I ++++
Sbjct:   35 LPNGFTGIYIIFVGDTP-PHECYIPDSDSISEAWRNETIPMETVDGAARRSSCRRLHLETVRNYSQRN--IIPNVDVNVSEIPWEACQDGWIYSREIYQSTIVTEWDLVCDNAYKGPLTTSIHYVGVLVGTVLSGQLSDRFGRKPMLFVMMALQTVAITAQIFSPNWEIFTFIFCLVGAGGYSNYTIAFVLGSEILSPRIRVVFCSLGVFMGSAVGYMAMPAVAYFLRDWRSLLISMAASGLIYIPLWWLLSESPRWLLSQGKVEEAEAILKDAAKMNKVQVPEPIFTQAEVEDSLAMKER--KINIMVIVKSCNILSITMACASLWMIITISYYALLLNTSNLNGNPYLNCFLSAVTEVPAYIIALLLLRYCSRHICQSSTLFLGGVMILCVRLI--PIDLPAVAVLLEMLGKFGVTAAFCVVYSVTSELFPTVIRNTAMGCCSMAARIATILSPFIIYLGKYYKALPY-IVMGVLALSGAVITFILPETRGKVLPETIPQMQR 531

[Close]

BLAST of slc22a-3 vs. Ensembl Medaka
Match: si:dkey-166k12.1 (solute carrier family 22 member 13 [Source:NCBI gene;Acc:101165571])

HSP 1 Score: 178.718 bits (452), Expect = 1.472e-48
Identity = 126/442 (28.51%), Postives = 222/442 (50.23%), Query Frame = 3

Query:  453 SCNQFQSQDNSTIIPCQNGYNYTMKYFTSSIVTEWDLVCDRAILNALATSSFFVMSFFGAIISCSIADRFGRKVVLITAFMCLNLCEFAQTYITSIYVLIVFKLLAGIFQQGCFISGFTMTIELFSLRNRSNACLADTFSWTXXXXXXXXXXXXXRDWRNYFFWTSITMLPFCLVFY--HLPESIRWMMAKDQTKNAQILLKTATLYSNPPLPEKTFENYDKYKRKQESEKLPHYNVLHIFRETLLLRYQLINSFVWFTTAMTYYGVQVKVVEIG-NPFLNFFLSSLVEIPANILCFPIANKYGRKITIGLTNFLVGFSLFMGYILWKYLDSPWPAIIVFLVGKMLNTGIFNLIFMHVSEFFPTTLRTTAVGMSSSCARIGASFGAMIFQITLYHDSIAFVIVIGCCLLTGVLVFCLPETYRKKMPTSIEEIKQW-VAHKPI 1766
            S +     + +  +PC  G+ Y+ + F SS VTEWDLVC+RA LN+L +S +      G+++  ++ADR+GR+ VL+ +     +   A  +  +  V ++ +   G    G  I+ F +  E    + R  A +   +++     +L    Y IRDWR      +I+   F L+FY   LP+S RW++A D+T+ A  LL+ A L +   LP       +K++    S++   ++ + + R   + +  +I  ++WF   + YYG+ + V  +G N ++  F+  L+EIPA  L   I   + R+++  L+ FL    L    +L    D P     + +VGK   T  F +I+++ +E FPT +R T +G+SS  AR+G     +I  +  +  +   +I     LL  +L   LPET  + +P ++E+ + W V   P+
Sbjct:   73 SADALPPGNRTERVPCGRGWVYSSEVFESSTVTEWDLVCNRAGLNSLGSSVYMSGLLVGSVVFGAMADRYGRRFVLLLSIALQTVFGVAVAFAPNFPVYVLLRFAVGTTISGVIINAFVLGTEWTCTKRRMLAGIITDYTFGLGYMLLAGVAYLIRDWRK--LQLAISAPGFLLIFYIRVLPQSARWLLANDRTEEAIALLRKAALVNGRVLPPAV--QVEKWEILGGSKR--SHSAVDLVRTPQMRKRTVILFYIWFVNVLVYYGLSLGVSRLGTNLYMTQFVFGLIEIPARSLVL-IFLPFSRRLS--LSGFLAVGGLACLLMLTVPEDHPNVLTGLAMVGKFGITASFAIIYVYTAEIFPTVVRQTGIGVSSMFARMGGVLAPIINMLDSHSPATPLIIFGTSPLLGALLALALPETADRPLPDTLEDAENWDVRSAPV 505

[Close]

BLAST of slc22a-3 vs. Ensembl Medaka
Match: slc22a4 (solute carrier family 22 member 4 [Source:NCBI gene;Acc:101163192])

HSP 1 Score: 179.104 bits (453), Expect = 1.514e-48
Identity = 140/505 (27.72%), Postives = 235/505 (46.53%), Query Frame = 3

Query:  315 LPCVFSMYSFQFTGVKPDSFHCALPPNVS-----RESMIPKERTGDKWEFSSCNQFQ-------SQDNSTIIP-------------CQNGYNYTMKYFTSSIVTEWDLVCDRAILNALATSSFFVMSFFGAIISCSIADRFGRKVVLITAFMCLNLCEFAQTYITSIYVLIVFKLLAGIFQQGCFISGFTMTIELFSLRNRSNACLADTFSWTXXXXXXXXXXXX-XRDWRNYFFWTSITMLPFCLVFYHLPESIRWMMAKDQTKNAQILLKTATLYSNPPLPEKTFENYDKYKRKQESEKLPHYNVLHIFRETLLLRYQLINSFVWFTTAMTYYGVQVKVVEI-GNPFLNFFLSSLVEIPANILCFPIANKYGRKITIGLTNFLVGFSLFMGYILWKYLDSPWPAIIVFLVGKMLNTGIFNLIFMHVSEFFPTTLRTTAVGMSSSCARIGASFGAMIFQITLYHDSIAFVIVIGCCLLTG-VLVFCLPETYRKKMPTSIEEIKQ 1745
            LP  F+     F G  P    C +P + S     R   IP E        SSC +         SQ N  IIP             CQ+G+ Y+ + + S+IVTEWDLVCD A    L TS  +V    G ++S  ++DRFGRK +L        +   AQ +  +  +      L G      +   F +  E+ S R R   C    F  +   ++ +  + + +RDWR+     + + L +  +++ L ES RW++++ + + A+ +LK A   +   +PE  F   +        E+    N++ I +   +L   +  + +W    ++YY + +    + GNP+LN FLS++ E+PA I+   +     R I    T FL G  +    ++   +D P  A+++ ++GK   T  F +++   SE FPT +R TA+G  S  ARI       I  +  Y+ ++ + IV+G   L+G V+ F LPET  K +P +I ++++
Sbjct:   35 LPNGFTGIYIIFVGDTPP-HECYIPDSDSISEAWRNETIPMETVDGAARRSSCRRLHLETVRNYSQRN--IIPNVDVNVSEIPWEACQDGWIYSREIYQSTIVTEWDLVCDNAYKGPLTTSIHYVGVLVGTVLSGQLSDRFGRKPMLFVMMALQTVAITAQIFSPNWEIFTFIFCLVGAGGYSNYTIAFVLGSEILSPRIRVVFCSLGVFMGSAVGYMAMPAVAYFLRDWRSLLISMAASGLIYIPLWWLLSESPRWLLSQGKVEEAEAILKDAAKMNKVQVPEPIFTQAEVEDSLAMKER--KINIMVIVKSCNILSITMACASLWMIITISYYALLLNTSNLNGNPYLNCFLSAVTEVPAYIIALLLLRYCSRHICQSSTLFLGGVMILCVRLI--PIDLPAVAVLLEMLGKFGVTAAFCVVYSVTSELFPTVIRNTAMGCCSMAARIATILSPFIIYLGKYYKALPY-IVMGVLALSGAVITFILPETRGKVLPETIPQMQR 531

[Close]

BLAST of slc22a-3 vs. Planmine SMEST
Match: SMESG000031472.1 (SMESG000031472.1)

HSP 1 Score: 1027.31 bits (2655), Expect = 0.000e+0
Identity = 513/517 (99.23%), Postives = 514/517 (99.42%), Query Frame = 3

Query:  228 MDPEKCLDELGGKNIWILKWFLLISFMKSLPCVFSMYSFQFTGVKPDSFHCALPPNVSRESMIPKERTGDKWEFSSCNQFQSQDNSTIIPCQNGYNYTMKYFTSSIVTEWDLVCDRAILNALATSSFFVMSFFGAIISCSIADRFGRKVVLITAFMCLNLCEFAQTYITSIYVLIVFKLLAGIFQQGCFISGFTMTIELFSLRNRSNACLADTFSWTXXXXXXXXXXXXXRDWRNYFFWTSITMLPFCLVFYHLPESIRWMMAKDQTKNAQILLKTATLYSNPPLPEKTFENYDKYKRKQESEKLPHYNVLHIFRETLLLRYQLINSFVWFTTAMTYYGVQVKVVEIGNPFLNFFLSSLVEIPANILCFPIANKYGRKITIGLTNFLVGFSLFMGYILWKYLDSPWPAIIVFLVGKMLNTGIFNLIFMHVSEFFPTTLRTTAVGMSSSCARIGASFGAMIFQITLYHDSIAFVIVIGCCLLTGVLVFCLPETYRKKMPTSIEEIKQWVAHKPIISFH 1778
            MDPEKCLDELGGKN WILKWFLLISFMKSLPCVFSMYSFQFTGVKPDSFHCALPPNVSRESMIPKE TGDKW+FSSCNQFQSQDNSTIIPCQ GYNYTMKYFTSSIVTEWDLVCDRAILNALATSSFFVMSFFGAIISCSIADRFGRKVVLITAFMCLNLCEFAQTYITSIYVLIVFKLLAGIFQQGCFISGFTMTIELFSLRNRSNACLADTFSWTFSSFILIIYIYFIRDWRNYFFWTSITMLPFCLVFYHLPESIRWMMAKDQTKNAQILLKTATLYSNPPLPEKTFENYDKYKRKQESEKLPHYNVLHIFRETLLLRYQLINSFVWFTTAMTYYGVQVKVVEIGNPFLNFFLSSLVEIPANILCFPIANKYGRKITIGLTNFLVGFSLFMGYILWKYLDSPWPAIIVFLVGKMLNTGIFNLIFMHVSEFFPTTLRTTAVGMSSSCARIGASFGAMIFQITLYHDSIAFVIVIGCCLLTGVLVFCLPETYRKKMPTSIEEIKQWVAHKPIISFH
Sbjct:    1 MDPEKCLDELGGKNKWILKWFLLISFMKSLPCVFSMYSFQFTGVKPDSFHCALPPNVSRESMIPKEWTGDKWKFSSCNQFQSQDNSTIIPCQKGYNYTMKYFTSSIVTEWDLVCDRAILNALATSSFFVMSFFGAIISCSIADRFGRKVVLITAFMCLNLCEFAQTYITSIYVLIVFKLLAGIFQQGCFISGFTMTIELFSLRNRSNACLADTFSWTFSSFILIIYIYFIRDWRNYFFWTSITMLPFCLVFYHLPESIRWMMAKDQTKNAQILLKTATLYSNPPLPEKTFENYDKYKRKQESEKLPHYNVLHIFRETLLLRYQLINSFVWFTTAMTYYGVQVKVVEIGNPFLNFFLSSLVEIPANILCFPIANKYGRKITIGLTNFLVGFSLFMGYILWKYLDSPWPAIIVFLVGKMLNTGIFNLIFMHVSEFFPTTLRTTAVGMSSSCARIGASFGAMIFQITLYHDSIAFVIVIGCCLLTGVLVFCLPETYRKKMPTSIEEIKQWVAHKPIISFH 517

[Close]

BLAST of slc22a-3 vs. Planmine SMEST
Match: SMESG000040243.1 (SMESG000040243.1)

HSP 1 Score: 142.51 bits (358), Expect = 8.241e-36
Identity = 131/523 (25.05%), Postives = 244/523 (46.65%), Query Frame = 3

Query:  273 WILKWFLLISFMKSLPCVFSMYSFQFTGVKPDS---FHCALPPNVSRESMIPK-----ERTGDKWEFSSC--------------------NQFQSQDNSTIIPCQNGYNYTMKYFTSSIVTEWDLVCDRAILNALATSSFFVMSFFGAIISCSIADRFGR-KVVLITAFMCLNLCEFAQTYITSIYVLIV-FKLLAGIFQQGCFISGFTMTIELFSLRNRSNACLADTFSWTXXXXXXXXXXXXXRDWRNYFFWTSITMLPFCLVFYHLPESIRWMMAKDQTKNAQILL----KTATLYSNPPLPEKTFENYDKYKRKQESEKLPHYNVLHIFRETLLLRYQLINSFVWFTTAMTYYGVQVKVVEI-GNPFLNFFLSSLVEIPANILCFPIANKYGRKITIGLTNFLVGFSLFMGYILWKYLDSPWPAIIVFLVGKMLNTGIFNLIFMHVSEFFPTTLRTTAVGMSSSCARIGASFGAMIFQITLYHDSIAFVIVIGCCLLTGVLVFCLPETYRKKMPTSIEE 1736
            ++L W  L++   S+  VF M   +F   KPD+   +   L  N +  S I       +++ D ++ S C                    ++   Q+ +    C NG+ Y+ + + S+   E+DLVCD   + +   + FF    FGA+I   ++D  GR +  LI   +  NL      Y +   ++I  F LL G  Q G  ++ F +  EL     R          +T +  ++ +  + +++WR    ++ +  + F   F+ + ES RW+++K ++K A I++    KT  +  +  L  +  ++++  + K ++EK   ++V  + +   +L   L   F W   A+ YYG+   V  + G+ +LNF L  LVEIPA +L     ++ GR+  + ++ +  G +  +   + KY ++   A I  ++GK+  T  + +++ + SE FPTT+R  A+G+SS  ARIG +    I  +  Y   +  +I      + G L F +PET  K +  +  +
Sbjct:   22 FLLCWPFLMAGFLSVDVVFLMAVPEFV-CKPDNVTMYKLQLLSNTTSVSKIADILILLQKSMDNYKTSRCYSWNTSMIMNLTSINLIANRSRLDFQNVTLDSKCSNGFIYSTQSYGSTAPNEYDLVCDSDYIRSNLKTIFFAGRIFGAVIFGQLSDIIGRLRTFLIV--VVFNLIAGLGLYFSINPIMIGGFLLLQGFSQVGYTLTTFVLGCELVGTSKRKWTGTVLQLFYTAAFILIPLCYWGMQNWRYLALFSGLPSIFFLSYFFIVYESPRWLLSKGRSKEALIIIEKVGKTNHIKLSENLKTEILKHHESEEYKNDTEK--KHSVFDLIKSKSMLLLSLNVWFNWIVNALIYYGIIYNVENLAGSLYLNFILLGLVEIPAYVLNLLFLDRIGRRNLLIISLWGTGVACLLSGCVPKY-NTVIIATIA-MIGKLTVTMSYGVVYFYTSELFPTTVRNAAMGVSSMSARIGGTMATPILLLDHYFSPLPMIIFAVLSAVAGGLTFKMPETKGKPLDQNFHK 537

[Close]

BLAST of slc22a-3 vs. Planmine SMEST
Match: SMESG000040243.1 (SMESG000040243.1)

HSP 1 Score: 140.969 bits (354), Expect = 1.764e-35
Identity = 112/420 (26.67%), Postives = 207/420 (49.29%), Query Frame = 3

Query:  498 CQNGYNYTMKYFTSSIVTEWDLVCDRAILNALATSSFFVMSFFGAIISCSIADRFGR-KVVLITAFMCLNLCEFAQTYITSIYVLIV-FKLLAGIFQQGCFISGFTMTIELFSLRNRSNACLADTFSWTXXXXXXXXXXXXXRDWRNYFFWTSITMLPFCLVFYHLPESIRWMMAKDQTKNAQILL----KTATLYSNPPLPEKTFENYDKYKRKQESEKLPHYNVLHIFRETLLLRYQLINSFVWFTTAMTYYGVQVKVVEI-GNPFLNFFLSSLVEIPANILCFPIANKYGRKITIGLTNFLVGFSLFMGYILWKYLDSPWPAIIVFLVGKMLNTGIFNLIFMHVSEFFPTTLRTTAVGMSSSCARIGASFGAMIFQITLYHDSIAFVIVIGCCLLTGVLVFCLPETYRKKMPTSIEE 1736
            C NG+ Y+ + + S+   E+DLVCD   + +   + FF    FGA+I   ++D  GR +  LI   +  NL      Y +   ++I  F LL G  Q G  ++ F +  EL     R          +T +  ++ +  + +++WR    ++ +  + F   F+ + ES RW+++K ++K A I++    KT  +  +  L  +  ++++  + K ++EK   ++V  + +   +L   L   F W   A+ YYG+   V  + G+ +LNF L  LVEIPA +L     ++ GR+  + ++ +  G +  +   + KY ++   A I  ++GK+  T  + +++ + SE FPTT+R  A+G+SS  ARIG +    I  +  Y   +  +I      + G L F +PET  K +  +  +
Sbjct:   83 CSNGFIYSTQSYGSTAPNEYDLVCDSDYIRSNLKTIFFAGRIFGAVIFGQLSDIIGRLRTFLIV--VVFNLIAGLGLYFSINPIMIGGFLLLQGFSQVGYTLTTFVLGCELVGTSKRKWTGTVLQLFYTAAFILIPLCYWGMQNWRYLALFSGLPSIFFLSYFFIVYESPRWLLSKGRSKEALIIIEKVGKTNHIKLSENLKTEILKHHESEEYKNDTEK--KHSVFDLIKSKSMLLLSLNVWFNWIVNALIYYGIIYNVENLAGSLYLNFILLGLVEIPAYVLNLLFLDRIGRRNLLIISLWGTGVACLLSGCVPKY-NTVIIATIA-MIGKLTVTMSYGVVYFYTSELFPTTVRNAAMGVSSMSARIGGTMATPILLLDHYFSPLPMIIFAVLSAVAGGLTFKMPETKGKPLDQNFHK 496

[Close]

BLAST of slc22a-3 vs. Planmine SMEST
Match: SMESG000040243.1 (SMESG000040243.1)

HSP 1 Score: 140.584 bits (353), Expect = 2.132e-35
Identity = 112/420 (26.67%), Postives = 207/420 (49.29%), Query Frame = 3

Query:  498 CQNGYNYTMKYFTSSIVTEWDLVCDRAILNALATSSFFVMSFFGAIISCSIADRFGR-KVVLITAFMCLNLCEFAQTYITSIYVLIV-FKLLAGIFQQGCFISGFTMTIELFSLRNRSNACLADTFSWTXXXXXXXXXXXXXRDWRNYFFWTSITMLPFCLVFYHLPESIRWMMAKDQTKNAQILL----KTATLYSNPPLPEKTFENYDKYKRKQESEKLPHYNVLHIFRETLLLRYQLINSFVWFTTAMTYYGVQVKVVEI-GNPFLNFFLSSLVEIPANILCFPIANKYGRKITIGLTNFLVGFSLFMGYILWKYLDSPWPAIIVFLVGKMLNTGIFNLIFMHVSEFFPTTLRTTAVGMSSSCARIGASFGAMIFQITLYHDSIAFVIVIGCCLLTGVLVFCLPETYRKKMPTSIEE 1736
            C NG+ Y+ + + S+   E+DLVCD   + +   + FF    FGA+I   ++D  GR +  LI   +  NL      Y +   ++I  F LL G  Q G  ++ F +  EL     R          +T +  ++ +  + +++WR    ++ +  + F   F+ + ES RW+++K ++K A I++    KT  +  +  L  +  ++++  + K ++EK   ++V  + +   +L   L   F W   A+ YYG+   V  + G+ +LNF L  LVEIPA +L     ++ GR+  + ++ +  G +  +   + KY ++   A I  ++GK+  T  + +++ + SE FPTT+R  A+G+SS  ARIG +    I  +  Y   +  +I      + G L F +PET  K +  +  +
Sbjct:   95 CSNGFIYSTQSYGSTAPNEYDLVCDSDYIRSNLKTIFFAGRIFGAVIFGQLSDIIGRLRTFLIV--VVFNLIAGLGLYFSINPIMIGGFLLLQGFSQVGYTLTTFVLGCELVGTSKRKWTGTVLQLFYTAAFILIPLCYWGMQNWRYLALFSGLPSIFFLSYFFIVYESPRWLLSKGRSKEALIIIEKVGKTNHIKLSENLKTEILKHHESEEYKNDTEK--KHSVFDLIKSKSMLLLSLNVWFNWIVNALIYYGIIYNVENLAGSLYLNFILLGLVEIPAYVLNLLFLDRIGRRNLLIISLWGTGVACLLSGCVPKY-NTVIIATIA-MIGKLTVTMSYGVVYFYTSELFPTTVRNAAMGVSSMSARIGGTMATPILLLDHYFSPLPMIIFAVLSAVAGGLTFKMPETKGKPLDQNFHK 508

[Close]

BLAST of slc22a-3 vs. Planmine SMEST
Match: SMESG000004219.1 (SMESG000004219.1)

HSP 1 Score: 99.7525 bits (247), Expect = 9.626e-22
Identity = 132/530 (24.91%), Postives = 242/530 (45.66%), Query Frame = 3

Query:  228 MDPEKCLDELGGKNIWILKWFLLISFMKSLPCVFSMYSFQFTGVK----PDSFHCALPPNVS---RES--MIPKERTGDKWEFSSCNQFQSQDNSTIIPCQNGYNYTMKYFTSSIVTEWDLVCDRAILNALATSSFFVMSFFGAIISCSIADRFGRKVVLITAFMCLNLCEFAQTYITSIYVLIVFKLLAGIFQQGCFISGFTMTIELFSLRNRSNACLADTFSWTXXX---XXXXXXXXXXRDWRNYFFWTSITMLPFCLVFYHLPESIRWMMAKDQTKNAQILLKTATLYSNPPLPEKTFENYDKYKRKQESEKLPHYNVLHIFRETLLLRYQLINSFVWFTTAMTYYGVQVKVV-EIGNPFLNFFLSSLVEIPANILCFPIANKYGRKITI-GLTNFLVGFSLFMGYILWKYLDS---PWPAIIVFLVGKMLNTGIFNLIFMHVSEFFPTTLRTTAVGMSSSCARIGASFGAMIFQITL-YHDSIAFVIVIGCCLLTGVLVFC-LPETYRKKMPTSIEEIKQWVAHK 1760
            MD E    ++GG  +     F  ISFM +L      Y  +F G+        F C L  N+S   R S  +I K++           Q++   N +   C + + +  ++  ++++ E +LVCDRA    L  ++FFV   F    S  ++D  G++++LI +     +    Q     I+  +V   ++G+ +       +T  IE+  +   S+  LA T  W   S    ++ ++ Y  R WR  +  + IT + + L F+ +PE+ RW+M   +   A    KT +  +         E ++K+K  Q+      +N+L    +T++ R+ ++N F  +  +  Y G    +     N F+  F+  L+E+P   L   +ANK GRK ++  L+   +   + M +I    L S   PW  + + +  K+  +  + +  +  +E  PTT R TA+ +      +G+ F  MI  + L ++ +  F++     L+T VLVF  +PET+   +P +IE+    + HK
Sbjct:    1 MDYEHLNAKIGGCGL-----FHYISFM-TLSITTFKYVVEFQGLTFALYEPKFSC-LVKNISSTIRNSTNLISKDQC----------QYRLSVNDSWNKC-DQWTFEKRFMRNTLINELNLVCDRAFYRELIFTTFFVGCLFSFPFSI-LSDSIGKRLLLIVSIFLSTIITIGQMVSYQIWQQLVLSFVSGVCKSVYVSLAYTTLIEIIPV---SHIDLAATNFWNLYSFGYMLVALFAYIFRSWRQIYILSLITSIFYVLYFWFVPETPRWLMLNKRRNEA---FKTMSFIAKINKCTLNKEEFNKWKPIQQVTG-KFWNLLK--HKTMIYRFLILN-FAGWAFSFAYIGSATDLTFASENIFITTFVMGLIELPTGPLSGIMANKLGRKKSVSALSGLGIICLIIMPFIEADSLKSVWQPWLKVCLAMGAKLGFSSAWLIFDIITNELIPTTDRNTAMSLVYITVGLGSIFAPMIHSVLLQFYFAGPFLLYSLLLLITVVLVFAFIPETHHLPVPQTIEQAVSLLIHK 501

The following BLAST results are available for this feature:

BLAST of slc22a-3 vs. Ensembl Human
BLAST of slc22a-3 vs. Ensembl Celegans
BLAST of slc22a-3 vs. Ensembl Fly
BLAST of slc22a-3 vs. Ensembl Zebrafish
BLAST of slc22a-3 vs. Ensembl Xenopus
BLAST of slc22a-3 vs. Ensembl Mouse
BLAST of slc22a-3 vs. UniProt/SwissProt
BLAST of slc22a-3 vs. TrEMBL
BLAST of slc22a-3 vs. Ensembl Cavefish
BLAST of slc22a-3 vs. Ensembl Sea Lamprey
BLAST of slc22a-3 vs. Ensembl Yeast
BLAST of slc22a-3 vs. Ensembl Nematostella
BLAST of slc22a-3 vs. Ensembl Medaka
BLAST of slc22a-3 vs. Planmine SMEST

BLAST of slc22a-3 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
SLC22A7	2.372e-47	25.93	solute carrier family 22 member 7 [Source:HGNC Sym...	[more]
SLC22A7	3.515e-47	25.89	solute carrier family 22 member 7 [Source:HGNC Sym...	[more]
SLC22A7	1.544e-45	25.79	solute carrier family 22 member 7 [Source:HGNC Sym...	[more]
SLC22A5	5.194e-43	25.77	solute carrier family 22 member 5 [Source:HGNC Sym...	[more]
SLC22A16	7.927e-40	24.75	solute carrier family 22 member 16 [Source:HGNC Sy...	[more]

BLAST of slc22a-3 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5


Match Name	E-value	Identity	Description
oct-1	1.127e-44	25.42	Organic cation transporter 1 [Source:UniProtKB/Sw...	[more]
oct-1	1.127e-44	25.42	Organic cation transporter 1 [Source:UniProtKB/Sw...	[more]
oct-1	1.586e-44	25.42	Organic cation transporter 1 [Source:UniProtKB/Sw...	[more]
B0252.3	4.624e-32	25.44	Putative transporter B0252.3 [Source:UniProtKB/Sw...	[more]
B0252.3	4.957e-32	25.44	Putative transporter B0252.3 [Source:UniProtKB/Sw...	[more]

BLAST of slc22a-3 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Balat	3.253e-44	23.22	gene:FBgn0033778 transcript:FBtr0087815	[more]
CG6126	2.613e-39	27.25	gene:FBgn0038407 transcript:FBtr0083278	[more]
Orct	3.449e-39	25.40	gene:FBgn0019952 transcript:FBtr0334870	[more]
Orct	3.449e-39	25.40	gene:FBgn0019952 transcript:FBtr0084599	[more]
CG4630	2.749e-34	23.96	gene:FBgn0033809 transcript:FBtr0087765	[more]

BLAST of slc22a-3 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
slc22a7a	1.927e-50	26.10	solute carrier family 22 member 7a [Source:ZFIN;Ac...	[more]
slc22a7b.1	7.836e-49	26.06	solute carrier family 22 member 7b, tandem duplica...	[more]
slc22a7b.3	1.335e-47	26.64	solute carrier family 22 member 7b, tandem duplica...	[more]
slc22a7b.3	1.810e-47	26.89	solute carrier family 22 member 7b, tandem duplica...	[more]
BX005258.2	2.926e-47	26.74	solute carrier family 22 member 7b, tandem duplica...	[more]

BLAST of slc22a-3 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5


Match Name	E-value	Identity	Description
slc22a4	2.134e-49	26.88	solute carrier family 22 (organic cation/zwitterio...	[more]
slc22a4	2.328e-49	26.24	solute carrier family 22 (organic cation/zwitterio...	[more]
ccdc30	1.163e-48	28.63	coiled-coil domain containing 30 [Source:Xenbase;A...	[more]
slc22a4	2.228e-48	26.55	solute carrier family 22 (organic cation/zwitterio...	[more]
emc2	9.922e-46	25.97	ER membrane protein complex subunit 2 [Source:Xenb...	[more]

BLAST of slc22a-3 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Slc22a7	7.111e-48	25.14	solute carrier family 22 (organic anion transporte...	[more]
Slc22a8	1.227e-42	28.81	solute carrier family 22 (organic anion transporte...	[more]
Slc22a8	1.227e-42	28.81	solute carrier family 22 (organic anion transporte...	[more]
Slc22a21	1.906e-42	25.54	solute carrier family 22 (organic cation transport...	[more]
Slc22a5	5.394e-41	26.35	solute carrier family 22 (organic cation transport...	[more]

BLAST of slc22a-3 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|Q66KG0\|S22AG_XENLA	1.742e-49	27.49	Solute carrier family 22 member 16 OS=Xenopus laev...	[more]
sp\|A6QLW8\|S22A7_BOVIN	2.091e-48	26.87	Solute carrier family 22 member 7 OS=Bos taurus OX...	[more]
sp\|Q5RLM2\|S22A7_RAT	1.264e-47	26.07	Solute carrier family 22 member 7 OS=Rattus norveg...	[more]
sp\|Q91WU2\|S22A7_MOUSE	2.793e-47	25.14	Solute carrier family 22 member 7 OS=Mus musculus ...	[more]
sp\|Q3YAW7\|S22A7_RABIT	3.704e-47	26.92	Solute carrier family 22 member 7 OS=Oryctolagus c...	[more]

BLAST of slc22a-3 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
A0A0H3YJ39	0.000e+0	100.00	Slc22a-3 OS=Schmidtea mediterranea OX=79327 GN=slc...	[more]
C3ZR16	6.387e-58	27.79	MFS domain-containing protein OS=Branchiostoma flo...	[more]
R7UIT7	1.485e-57	31.10	MFS domain-containing protein (Fragment) OS=Capite...	[more]
A0A3P8XC61	1.609e-56	27.91	MFS domain-containing protein OS=Esox lucius OX=80...	[more]
A0A093JNL3	3.658e-55	27.95	Solute carrier family 22 member 7 (Fragment) OS=St...	[more]

BLAST of slc22a-3 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ENSAMXT00000010878.2	5.293e-53	26.50	pep primary_assembly:Astyanax_mexicanus-2.0:14:292...	[more]
ENSAMXT00000043421.1	2.662e-50	25.14	pep primary_assembly:Astyanax_mexicanus-2.0:APWO02...	[more]
slc22a7b.2	5.378e-48	26.42	solute carrier family 22 member 7b, tandem duplica...	[more]
slc22a5	1.253e-47	26.64	solute carrier family 22 member 4-like [Source:NCB...	[more]
slc22a7a	2.156e-47	25.61	solute carrier family 22 member 7a [Source:ZFIN;Ac...	[more]

BLAST of slc22a-3 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5


Match Name	E-value	Identity	Description
oct2	1.123e-31	22.07	organic cation transporter 2 [Source:ZFIN;Acc:ZDB-...	[more]
SLC22A7	6.517e-22	23.74	solute carrier family 22 member 7 [Source:HGNC Sym...	[more]
si:dkey-190l8.2	6.431e-21	23.79	si:dkey-190l8.2 [Source:ZFIN;Acc:ZDB-GENE-030131-9...	[more]
ENSPMAT00000007122.1	1.901e-17	25.62	pep scaffold:Pmarinus_7.0:GL476962:153150:164773:-...	[more]
slc22a6l	1.067e-16	22.93	solute carrier family 22 member 6, like [Source:NC...	[more]

BLAST of slc22a-3 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 1


Match Name	E-value	Identity	Description
CIN10	1.835e-6	24.30	Putative transporter; member of the sugar porter f...	[more]

BLAST of slc22a-3 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5


Match Name	E-value	Identity	Description
EDO47316	3.258e-49	29.29	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO27829	5.883e-49	27.70	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO36597	5.567e-48	29.52	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO46087	1.025e-42	27.85	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO46581	1.260e-42	28.25	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of slc22a-3 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5


Match Name	E-value	Identity	Description
slc22a7a	3.970e-51	28.08	solute carrier family 22 member 7 [Source:NCBI gen...	[more]
slc22a7b.3	6.598e-50	26.92	solute carrier family 22 member 7-like [Source:NCB...	[more]
slc22a4	9.107e-49	27.72	solute carrier family 22 member 4 [Source:NCBI gen...	[more]
si:dkey-166k12.1	1.472e-48	28.51	solute carrier family 22 member 13 [Source:NCBI ge...	[more]
slc22a4	1.514e-48	27.72	solute carrier family 22 member 4 [Source:NCBI gen...	[more]

BLAST of slc22a-3 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5


Match Name	E-value	Identity	Description
SMESG000031472.1	0.000e+0	99.23	SMESG000031472.1	[more]
SMESG000040243.1	8.241e-36	25.05	SMESG000040243.1	[more]
SMESG000040243.1	1.764e-35	26.67	SMESG000040243.1	[more]
SMESG000040243.1	2.132e-35	26.67	SMESG000040243.1	[more]
SMESG000004219.1	9.626e-22	24.91	SMESG000004219.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Cross References

External references for this transcript


Database	Accession
SmedGD GBrowse	SMED30028480
GenBank	AKN21551.1

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30028480 ID=SMED30028480|Name=slc22a-3|organism=Schmidtea mediterranea sexual|type=transcript|length=1868bp
ATTCTGAGATGATAAAACCAATTTTAAAGAGAGAACGAAAATAGAAAAGA
GAGATAATTGAAAATCAAATTAAATTGACATCATTAATTGAAAAATATTC
CAAATCTGAATTTTCTACGTGAAATTCTGTATTAATTATTTAAATTAGTC
AATCATGAACTTTAATCGCATTGACAGTGTTATGTATCGAATAATACTAT
GTAAGAATAAACAGTTCTAGACTTGAAATGGACCCAGAAAAATGCCTTGA
CGAGCTCGGAGGGAAGAACATATGGATTCTGAAGTGGTTTCTGTTGATTT
CCTTTATGAAATCACTGCCATGTGTGTTCTCAATGTATTCGTTTCAATTT
ACCGGCGTCAAACCAGACAGCTTTCATTGTGCACTCCCTCCGAATGTGTC
AAGGGAAAGCATGATACCCAAAGAACGGACTGGCGACAAGTGGGAATTTA
GTTCATGCAATCAGTTCCAGAGTCAAGATAACAGTACTATAATTCCTTGT
CAAAATGGATACAATTATACAATGAAGTATTTCACTTCCTCTATTGTCAC
TGAATGGGATCTAGTCTGTGATCGGGCGATTTTGAACGCATTGGCAACTA
GCTCGTTTTTTGTTATGTCATTTTTCGGTGCAATTATTAGCTGTAGTATT
GCTGATAGATTTGGACGGAAAGTTGTTTTGATTACTGCGTTTATGTGCCT
AAACCTCTGTGAGTTTGCCCAAACTTATATCACTAGTATATATGTTTTAA
TCGTTTTTAAATTATTGGCCGGGATCTTTCAACAGGGTTGTTTTATATCT
GGATTTACTATGACCATCGAATTGTTTTCTTTGAGAAACCGCAGCAATGC
CTGCCTGGCTGATACGTTTTCTTGGACGTTTTCTAGCTTCATTTTAATCA
TATATATCTATTTTATAAGAGATTGGAGAAATTATTTTTTTTGGACTTCA
ATAACGATGTTGCCGTTTTGTTTAGTATTTTATCATTTACCAGAAAGCAT
TCGTTGGATGATGGCAAAAGACCAAACAAAAAATGCTCAAATATTACTTA
AAACTGCTACTTTATACTCAAATCCTCCTCTGCCTGAGAAAACATTTGAA
AACTATGACAAATACAAAAGAAAGCAGGAATCGGAAAAGTTGCCGCATTA
TAATGTTCTACACATTTTCCGTGAAACTCTCTTGCTGAGATATCAGTTGA
TTAATTCGTTTGTTTGGTTTACCACGGCAATGACATATTACGGGGTGCAG
GTAAAAGTCGTTGAAATTGGAAACCCTTTTCTCAATTTCTTCCTATCGTC
TTTGGTAGAAATTCCAGCAAACATATTATGTTTTCCAATCGCTAACAAAT
ACGGTCGCAAAATTACAATCGGATTGACAAATTTCTTAGTTGGATTTTCC
CTCTTTATGGGATATATATTGTGGAAGTACTTGGATAGTCCATGGCCGGC
TATAATTGTATTTTTAGTCGGGAAGATGCTAAACACGGGAATATTTAATT
TGATTTTTATGCATGTCAGTGAGTTTTTCCCGACAACTCTACGAACAACA
GCAGTTGGAATGTCAAGCTCCTGCGCTAGAATAGGAGCTTCATTTGGGGC
AATGATATTTCAAATTACACTTTATCACGATTCGATTGCATTTGTTATTG
TAATTGGATGCTGTTTGTTGACAGGGGTTCTGGTGTTTTGTCTCCCTGAA
ACTTACCGAAAAAAGATGCCGACTTCTATTGAAGAAATTAAACAATGGGT
AGCTCACAAGCCTATTATAAGTTTTCATTAATTTTACAAAAACAATTTTT
AACTCTTGATTTAATACATTTTATATGATGCACTTCAAAACTTGTACTAG
AACACATTTCAATTGTAG

protein sequence of SMED30028480-orf-1

>SMED30028480-orf-1 ID=SMED30028480-orf-1|Name=SMED30028480-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=518bp
MDPEKCLDELGGKNIWILKWFLLISFMKSLPCVFSMYSFQFTGVKPDSFH
CALPPNVSRESMIPKERTGDKWEFSSCNQFQSQDNSTIIPCQNGYNYTMK
YFTSSIVTEWDLVCDRAILNALATSSFFVMSFFGAIISCSIADRFGRKVV
LITAFMCLNLCEFAQTYITSIYVLIVFKLLAGIFQQGCFISGFTMTIELF
SLRNRSNACLADTFSWTFSSFILIIYIYFIRDWRNYFFWTSITMLPFCLV
FYHLPESIRWMMAKDQTKNAQILLKTATLYSNPPLPEKTFENYDKYKRKQ
ESEKLPHYNVLHIFRETLLLRYQLINSFVWFTTAMTYYGVQVKVVEIGNP
FLNFFLSSLVEIPANILCFPIANKYGRKITIGLTNFLVGFSLFMGYILWK
YLDSPWPAIIVFLVGKMLNTGIFNLIFMHVSEFFPTTLRTTAVGMSSSCA
RIGASFGAMIFQITLYHDSIAFVIVIGCCLLTGVLVFCLPETYRKKMPTS
IEEIKQWVAHKPIISFH*

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000087	proximal tubule
PLANA:0000418	head
PLANA:0003116	parenchymal cell

Vocabulary: **INTERPRO**
Term	Definition
IPR036259	MFS_trans_sf
IPR005828	MFS_sugar_transport-like
IPR020846	MFS_dom
IPR001633	EAL_dom

Vocabulary: **molecular function**
Term	Definition
GO:0022857	transmembrane transporter activity

Vocabulary: **biological process**
Term	Definition
GO:0055085	transmembrane transport

Vocabulary: **cellular component**
Term	Definition
GO:0016021	integral component of membrane
GO:0016020	membrane

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
None	No IPR available	GENE3D	G3DSA:1.20.1250.20		coord: 92..506 e-value: 8.6E-57 score: 194.9
None	No IPR available	PANTHER	PTHR24064	FAMILY NOT NAMED	coord: 52..505
None	No IPR available	PANTHER	PTHR24064:SF411		coord: 52..505
None	No IPR available	CDD	cd17317	MFS_SLC22	coord: 94..490 e-value: 5.24419E-59 score: 196.262
None	No IPR available	TMHMM	TMhelix		coord: 443..465
None	No IPR available	TMHMM	TMhelix		coord: 182..201
None	No IPR available	TMHMM	TMhelix		coord: 20..42
None	No IPR available	TMHMM	TMhelix		coord: 350..372
None	No IPR available	TMHMM	TMhelix		coord: 155..177
None	No IPR available	TMHMM	TMhelix		coord: 318..340
None	No IPR available	TMHMM	TMhelix		coord: 235..254
None	No IPR available	TMHMM	TMhelix		coord: 208..230
None	No IPR available	TMHMM	TMhelix		coord: 120..142
None	No IPR available	TMHMM	TMhelix		coord: 408..430
None	No IPR available	TMHMM	TMhelix		coord: 379..398
None	No IPR available	TMHMM	TMhelix		coord: 470..489
IPR005828	Major facilitator, sugar transporter-like	PFAM	PF00083	Sugar_tr	coord: 116..495 e-value: 1.2E-24 score: 87.1
IPR020846	Major facilitator superfamily domain	PROSITE	PS50850	MFS	coord: 71..494 score: 18.715
IPR036259	MFS transporter superfamily	SUPERFAMILY	SSF103473	MFS general substrate transporter	coord: 121..497