Voltage dependent L type calcium channel subunit
Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30028403 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 13
Homology
BLAST of Voltage dependent L type calcium channel subunit vs. Ensembl Human
Match: CACNA1S (calcium voltage-gated channel subunit alpha1 S [Source:HGNC Symbol;Acc:HGNC:1397]) HSP 1 Score: 1231.47 bits (3185), Expect = 0.000e+0 Identity = 741/1613 (45.94%), Postives = 1011/1613 (62.68%), Query Frame = 2 Query: 641 SLAKRTINLSFPGMQTSTSKSLFIFSEENVIRKYAKIIIEWGPFEYMVLLTILANCIVLSMERHLPKKDKTLLAGQLELTEKYFLGIFCVEALLKIVALGFCCHKEAYLRNVWNIMDFVVVVTGFLMMFLN----IDNH-----SDSSTVDLRTLRAVRVLRPLKLVAGFPSLQVVLKSIIRAMAPLLQIGLLVLFAITIFAIIGLEFYSGAFHYTCFKANSDKLPLPIPTEKSLVPCSNSKNGSGLGAYTCPEDYQCKAYWEGPNYGITSFDNIGYAMLTVFQCITMEGWTDIMYHTNDAIGNRFNWLYFVPLIILGSFFMLNLVLGVLSGXXXXXXXXXXXXXXXLKLRRQQQTEKEFNGYMEWIQKAEEVLLNEATTTSEDKMRIIAARRRAEKQKYKLLGKNQSIPDFEYEDTELYSETKSMKGNIFIRSYAGIRRRRKERCTSFWRT-EKHFRFSVRRLVKSQPFYWAVIILVFFNTVCVAIEHYEQGKWLTLFLNYAEYVFLCLFMMEMMIKMYGLSIRVYFQSSFNIFDCVVIAGSLFEIIYGIFVQDSSFGLSVLRALRLLRIFKVTRYWAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXGMQLFGGEFNFEEGKPPQ-NFDTFVKALLTVFQILTGEDWNTVMYNGIQSKGGVKERGTVFSIYFVLLVVFGNYTLLNVFLAIAVDNLANXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSSDNFIGRLPLSIDPPMVQVCPPSPQTANSLISKNFSFDHNQVEVNDKGCLLNTNKPNGKLGMLGHDNTNFNSLESDPVPNKIEPETIQRK--PVLPYSAMFIFSPLNSLRRFCHFVVNLRYFDLFIMIVICASSIALAAEDPVKEKSLKNNILEFFDYAFTGVFTVEMILKIIDLGIILHPGSYCRDLWNILDATVVICALVAFIMGQKPSPTGNKLRGSSAKNLNTIKSLRVLRVLRPLKTINRVPKLKAVFDCVVSSLKNVFNILIVYILFQFIFAVIAVQLFQGKFFYCNDASKSSRETCRGYFFDYAGRS--TPETKKRLWQHHDFHFDNILYAMLTLFTVTTGEGWPTVLKNSMESTNIDNGPIADYRQEMAXXXXXXXXXXXXXXXXXXXALIIITFQEQGENELIDLDLDKNQKQCIDFAINEKPLCRYMPKDKTTIKYRVWRLVVSTPFEYFIMVMIALNTLILMMKYYREEKKASSAATHDREQQAYLNYCNTLIFLNSAFTVMFSIECVLKIMAFGPKNYFRDPWNIFDFITVIGSITDVLVSELQDXXXXXXXXXX---XXXXXXXXXXXXQGYTIRILLWTFIQSFKALPYVCLLIAMLFFIYSIIGMQVFGNIKLISEYQINRHNNFQTFTNGLLLLFRCATGESWQEIMLACDNNKPC--EKDIENTNNFDCGSNFTYIYFVSFIFLCSFLMLNLFVAVIMDNFDYLTRDSSILGPHHLDEYIRVWAEYDPGAIGRIHHSEMYEMLRNMEPPVGFGKKCPYRLAYRKLIRMNMPVDENGTVNFTTTLFALIRESLNIKMSTAEYMDIKDMELRQTICKMWPVQAKKKLNLIVPPDSELVFHKMTVGKIYAGYLIVENWRAYKNSQEQ 5419 L K+ P + ++LF + EN +RK I+EW PFE ++LLTI ANC+ L++ +P+ D L LE E +FL +F +EA +KI+A GF H++AYLR+ WN++DF +V G + L I +H S + +D++ LRA RVLRPL+LV+G PSLQVVL SI +AM PL I LLVLF + I+AIIGLE + G H TC+ +D + E S PC+ + G G +C+ W GPN+GIT FDN G++MLTV+QCITMEGWTD++Y NDAIGN + W+YFV LI+LGSFF+LNLVLGVLSGEF KERE+ + R F KLR +QQ +++ GYM WI + E + + E K+ + E Y++ G N+ I FIR WR + FR+ +VKS+ FYW VI++V NT+ +A EH+ Q WLT + A V L LF EM++KMYGL +R YF S FN FDC V+ + EI+ + G+SVLR +RLLRIFK+T+YW SL NLV SLLNS+RSI SLL LLFLFI+IFALLGMQLFGG ++FE+ + + NFD F +AL++VFQ+LTGEDW ++MYNGI + GG G + IYF++L V GNY LLNVFLAIAVDNLA A+ LT+A++ KA E +R + L ++ + + + + L P + P TA I + F+ N EV D P G D + + P P + ++ K P+ S+ FIFSP N +R CH +VN +F FI++ I SS ALAAEDP++ S++N IL+ FD FT VFTVE++LK+ G LH GS+CR+ +N+LD VV +L++ G + ++ +K LRVLRVLRPL+ INR LK V C+ ++ + NI++V L QF+FA I VQLF+GKFF C D SK + E CRGY++ Y E + R W H DFHFDN+L AM++LFTV+T EGWP +L +++S D GPI + R EMAIF+I++ I+ FF +NIFV +I+TFQEQGE E + +LDKNQ+QC+ +A+ +PL Y+PK+ +Y+VW +V S+ FEY + +I LNT+ L M++Y + ++ +N+ + + LN AFT++F++E +LK+MAF + YF DPWN+FDF+ VIGSI DV++SE+ D + LFR RLIKLL + +R LLWTFI+SF+ALPYV LLI MLFFIY++IGMQ+FG I L+ QINR+NNFQTF +LLLFRCATGE+WQEI+LAC K C E D + CG+NF Y YF+SF LC+FL++NLFVAVIMDNFDYLTRD SILGPHHLDE+ +WAEYDP A GRI H ++ +LR ++PP+GFGK CP+R+A ++L+ MNMP++ +GTV F TLFAL+R +L IK T + + ELR I K+W + K L+ ++PP + ++TVGK YA +LI E++R + QE+ Sbjct: 10 GLRKKQPKKPVPEILPRPPRALFCLTLENPLRKACISIVEWKPFETIILLTIFANCVALAVYLPMPEDDNNSLNLGLEKLEYFFLIVFSIEAAMKIIAYGFLFHQDAYLRSGWNVLDFTIVFLGVFTVILEQVNVIQSHTAPMSSKGAGLDVKALRAFRVLRPLRLVSGVPSLQVVLNSIFKAMLPLFHIALLVLFMVIIYAIIGLELFKGKMHKTCYFIGTDIVATVENEEPS--PCART----GSGRRCTINGSECRGGWPGPNHGITHFDNFGFSMLTVYQCITMEGWTDVLYWVNDAIGNEWPWIYFVTLILLGSFFILNLVLGVLSGEFTKEREKAKSRGTFQKLREKQQLDEDLRGYMSWITQGE---VMDVEDFREGKLSLDEGGSDTESL-YEIAGLNKIIQ--------------------FIRH---------------WRQWNRIFRWKCHDIVKSKVFYWLVILIVALNTLSIASEHHNQPLWLTRLQDIANRVLLSLFTTEMLMKMYGLGLRQYFMSIFNRFDCFVVCSGILEILLVESGAMTPLGISVLRCIRLLRIFKITKYWTSLSNLVASLLNSIRSIASLLLLLFLFIVIFALLGMQLFGGRYDFEDTEVRRSNFDNFPQALISVFQVLTGEDWTSMMYNGIMAYGGPSYPGMLVCIYFIILFVCGNYILLNVFLAIAVDNLAEAESLTSAQKAKAEEKKRRKMSKGLPDKSEEEKSTMAK-KLEQKPKGEGI----PTTAKLKIDE---FESNVNEVKD---------PYPSADFPGDDEEDEPEIPLSPRPRPLAELQLKEKAVPIPEASSFFIFSPTNKIRVLCHRIVNATWFTNFILLFILLSSAALAAEDPIRADSMRNQILKHFDIGFTSVFTVEIVLKMTTYGAFLHKGSFCRNYFNMLDLLVVAVSLISM--------------GLESSAISVVKILRVLRVLRPLRAINRAKGLKHVVQCMFVAISTIGNIVLVTTLLQFMFACIGVQLFKGKFFRCTDLSKMTEEECRGYYYVYKDGDPMQIELRHREWVHSDFHFDNVLSAMMSLFTVSTFEGWPQLLYKAIDSNAEDVGPIYNNRVEMAIFFIIYIILIAFFMMNIFVGFVIVTFQEQGETEYKNCELDKNQRQCVQYALKARPLRCYIPKNP--YQYQVWYIVTSSYFEYLMFALIMLNTICLGMQHYNQSEQ--------------MNHISDI--LNVAFTIIFTLEMILKLMAFKARGYFGDPWNVFDFLIVIGSIIDVILSEIDDPDESARISSAFFRLFRVMRLIKLLSRAEGVRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQMFGKIALVDGTQINRNNNFQTFPQAVLLLFRCATGEAWQEILLACSYGKLCDPESDYAPGEEYTCGTNFAYYYFISFYMLCAFLVINLFVAVIMDNFDYLTRDWSILGPHHLDEFKAIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKFCPHRVACKRLVGMNMPLNSDGTVTFNATLFALVRTALKIK--TEGNFEQANEELRAIIKKIWKRTSMKLLDQVIPPIGD---DEVTVGKFYATFLIQEHFRKFMKRQEE 1523
BLAST of Voltage dependent L type calcium channel subunit vs. Ensembl Human
Match: CACNA1C (calcium voltage-gated channel subunit alpha1 C [Source:HGNC Symbol;Acc:HGNC:1390]) HSP 1 Score: 1230.7 bits (3183), Expect = 0.000e+0 Identity = 768/1688 (45.50%), Postives = 1042/1688 (61.73%), Query Frame = 2 Query: 599 VMSIDDGSKTTSMRSLAKRTINLSFPGMQTSTS-----KSLFIFSEENVIRKYAKIIIEWGPFEYMVLLTILANCIVLSMERHLPKKDKTLLAGQLELTEKYFLGIFCVEALLKIVALGFCCHKEAYLRNVWNIMDFVVVVTGFLMMFLNIDNHSDSSTV--------DLRTLRAVRVLRPLKLVAGFPSLQVVLKSIIRAMAPLLQIGLLVLFAITIFAIIGLEFYSGAFHYTCFKANSDKLPLPIPTEKSLVPCSNSKNGSGLGAYTCPEDYQCKAYWEGPNYGITSFDNIGYAMLTVFQCITMEGWTDIMYHTNDAIGNRFNWLYFVPLIILGSFFMLNLVLGVLSGXXXXXXXXXXXXXXXLKLRRQQQTEKEFNGYMEWIQKAEEV-LLNEATTTSEDKMRIIAARRRAEKQKYKLLGKNQSIPDFEYEDTELYSETKSMKGNIFIRSYAGIR---RRRKERCTSFWRTEKHF-RFSVRRLVKSQPFYWAVIILVFFNTVCVAIEHYEQGKWLTLFLNYAEYVFLCLFMMEMMIKMYGLSIRVYFQSSFNIFDCVVIAGSLFEIIYGIFVQDSSFGLSVLRALRLLRIFKVTRYWAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXGMQLFGGEFNFEEGKPPQN-FDTFVKALLTVFQILTGEDWNTVMYNGIQSKGGVKERGTVFSIYFVLLVVFGNYTLLNVFLAIAVDNLANXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSSDNFIGRLPLSIDPPMVQVCPPSPQTANSLISKNFSFDHNQVEVNDKGCLLNTNK-PNGKLGMLGHDNTNFNSLESDPVPNKIEPETIQRK--PVLPYSAMFIFSPLNSLRRFCHFVVNLRYFDLFIMIVICASSIALAAEDPVKEKSLKNNILEFFDYAFTGVFTVEMILKIIDLGIILHPGSYCRDLWNILDATVVICALVAFIMGQKPSPTGNKLRGSSAKNLNTIKSLRVLRVLRPLKTINRVPKLKAVFDCVVSSLKNVFNILIVYILFQFIFAVIAVQLFQGKFFYCNDASKSSRETCRGYFFDYAGRST--PETKKRLWQHHDFHFDNILYAMLTLFTVTTGEGWPTVLKNSMESTNIDNGPIADYRQEMAXXXXXXXXXXXXXXXXXXXALIIITFQEQGENELIDLDLDKNQKQCIDFAINEKPLCRYMPKDKTTIKYRVWRLVVSTPFEYFIMVMIALNTLILMMKYYREEKKASSAATHDREQQAYLNYCNTLIFLNSAFTVMFSIECVLKIMAFGPKNYFRDPWNIFDFITVIGSITDVLVSE--------------LQDXXXXXXXXXXXXXXXXXXXXXXQGYTIRILLWTFIQSFKALPYVCLLIAMLFFIYSIIGMQVFGNIKLISEYQINRHNNFQTFTNGLLLLFRCATGESWQEIMLACDNNKPCEKDIENTNNFD----CGSNFTYIYFVSFIFLCSFLMLNLFVAVIMDNFDYLTRDSSILGPHHLDEYIRVWAEYDPGAIGRIHHSEMYEMLRNMEPPVGFGKKCPYRLAYRKLIRMNMPVDENGTVNFTTTLFALIRESLNIKMSTAEYMDIKDMELRQTICKMWPVQAKKKLNLIVPPDSELVFHKMTVGKIYAGYLIVENWRAYKNSQEQG----PRSSPAVSIKSVTK------PVVKEEKSANLLAK 5506 +M + +++ S ++ P Q ST+ ++L + +N IR+ I+EW PFE ++LLTI ANC+ L++ P+ D LE E FL IF VEA LK++A G H AYLRN WN++DF++VV G L +D + D++ LRA RVLRPL+LV+G PSLQVVL SII+AM PLL I LLVLF I I+AIIGLE + G H TC+ N + + +P E PC+ + G G C CK W+GP +GIT+FDN +AMLTVFQCITMEGWTD++Y NDA+G + W+YFV LII+GSFF+LNLVLGVLSGEF+KERE+ + R F KLR +QQ E++ GY++WI +AE++ NE E+K R N S+P E E T+++ G G R R K + + +WR F R R VKS FYW VI LVF NT+ +A EHY Q WLT + A L LF EM++KMY L ++ YF S FN FDC V+ G + E I S G+SVLR +RLLRIFK+TRYW SL NLV SLLNS+RSI SLL LLFLFI+IF+LLGMQLFGG+FNF+E + ++ FD F ++LLTVFQILTGEDWN+VMY+GI + GG G + IYF++L + GNY LLNVFLAIAVDNLA+A+ LT+A++E+ E +R A E+K ++ P V S+ + S ++ ++D N +K P G ++ + P P + ++ K P+ SA FIFS N R CH +VN F I+ I SSI+LAAEDPV+ S +N+IL DY FT +FT+E+ILK+ G LH GS+CR+ +NILD VV +L++F G + +N +K LRVLRVLRPL+ INR LK V CV +++ + NI+IV L QF+FA I VQLF+GK + C+D+SK + C+G + Y P + R W++ F FDN+L AM+ LFTV+T EGWP +L S++S D GPI +YR E++IF+I++ I+ FF +NIFV +I+TFQEQGE E + +LDKNQ+QC+++A+ +PL RY+PK++ +Y+VW +V ST FEY + V+I LNT+ L M++Y Q+ L + + LN FT +F++E +LK++AF PK YF DPWN+FDF+ VIGSI DV++SE +++S +S+ F RLFR RL+KLL +G IR LLWTFI+SF+ALPYV LLI MLFFIY++IGMQVFG I L +INR+NNFQTF +LLLFRCATGE+WQ+IMLAC K C + E +N+ + CGS+F YF+SF LC+FL++NLFVAVIMDNFDYLTRD SILGPHHLDE+ R+WAEYDP A GRI H ++ +LR ++PP+GFGK CP+R+A ++L+ MNMP++ +GTV F TLFAL+R +L IK T ++ + ELR I K+W + K L+ +VPP + ++TVGK YA +LI E +R +K +EQG P A+S+++ + P ++ S +L A+ Sbjct: 64 LMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISIVEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIAYGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCY--NQEGIA-DVPAEDDPSPCA-LETGHG---RQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCITMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGDFQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPR------------------NMSMPTSETESV----NTENVAGGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLTIASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGILETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYGGPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLARTASPEKKQE---------LVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNPETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDTIFTNLILFFILLSSISLAAEDPVQHTSFRNHILGNADYVFTSIFTLEIILKMTAYGAFLHKGSFCRNYFNILDLLVVSVSLISF--------------GIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGEVDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLRRYIPKNQH--QYKVWYVVNSTYFEYLMFVLILLNTICLAMQHY---------------GQSCL-FKIAMNILNMLFTGLFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVILSETNPAEHTQCSPSMNAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRIK--TEGNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGD---DEVTVGKFYATFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAE 1676
BLAST of Voltage dependent L type calcium channel subunit vs. Ensembl Human
Match: CACNA1C (calcium voltage-gated channel subunit alpha1 C [Source:HGNC Symbol;Acc:HGNC:1390]) HSP 1 Score: 1230.7 bits (3183), Expect = 0.000e+0 Identity = 768/1688 (45.50%), Postives = 1042/1688 (61.73%), Query Frame = 2 Query: 599 VMSIDDGSKTTSMRSLAKRTINLSFPGMQTSTS-----KSLFIFSEENVIRKYAKIIIEWGPFEYMVLLTILANCIVLSMERHLPKKDKTLLAGQLELTEKYFLGIFCVEALLKIVALGFCCHKEAYLRNVWNIMDFVVVVTGFLMMFLNIDNHSDSSTV--------DLRTLRAVRVLRPLKLVAGFPSLQVVLKSIIRAMAPLLQIGLLVLFAITIFAIIGLEFYSGAFHYTCFKANSDKLPLPIPTEKSLVPCSNSKNGSGLGAYTCPEDYQCKAYWEGPNYGITSFDNIGYAMLTVFQCITMEGWTDIMYHTNDAIGNRFNWLYFVPLIILGSFFMLNLVLGVLSGXXXXXXXXXXXXXXXLKLRRQQQTEKEFNGYMEWIQKAEEV-LLNEATTTSEDKMRIIAARRRAEKQKYKLLGKNQSIPDFEYEDTELYSETKSMKGNIFIRSYAGIR---RRRKERCTSFWRTEKHF-RFSVRRLVKSQPFYWAVIILVFFNTVCVAIEHYEQGKWLTLFLNYAEYVFLCLFMMEMMIKMYGLSIRVYFQSSFNIFDCVVIAGSLFEIIYGIFVQDSSFGLSVLRALRLLRIFKVTRYWAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXGMQLFGGEFNFEEGKPPQN-FDTFVKALLTVFQILTGEDWNTVMYNGIQSKGGVKERGTVFSIYFVLLVVFGNYTLLNVFLAIAVDNLANXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSSDNFIGRLPLSIDPPMVQVCPPSPQTANSLISKNFSFDHNQVEVNDKGCLLNTNK-PNGKLGMLGHDNTNFNSLESDPVPNKIEPETIQRK--PVLPYSAMFIFSPLNSLRRFCHFVVNLRYFDLFIMIVICASSIALAAEDPVKEKSLKNNILEFFDYAFTGVFTVEMILKIIDLGIILHPGSYCRDLWNILDATVVICALVAFIMGQKPSPTGNKLRGSSAKNLNTIKSLRVLRVLRPLKTINRVPKLKAVFDCVVSSLKNVFNILIVYILFQFIFAVIAVQLFQGKFFYCNDASKSSRETCRGYFFDYAGRST--PETKKRLWQHHDFHFDNILYAMLTLFTVTTGEGWPTVLKNSMESTNIDNGPIADYRQEMAXXXXXXXXXXXXXXXXXXXALIIITFQEQGENELIDLDLDKNQKQCIDFAINEKPLCRYMPKDKTTIKYRVWRLVVSTPFEYFIMVMIALNTLILMMKYYREEKKASSAATHDREQQAYLNYCNTLIFLNSAFTVMFSIECVLKIMAFGPKNYFRDPWNIFDFITVIGSITDVLVSE--------------LQDXXXXXXXXXXXXXXXXXXXXXXQGYTIRILLWTFIQSFKALPYVCLLIAMLFFIYSIIGMQVFGNIKLISEYQINRHNNFQTFTNGLLLLFRCATGESWQEIMLACDNNKPCEKDIENTNNFD----CGSNFTYIYFVSFIFLCSFLMLNLFVAVIMDNFDYLTRDSSILGPHHLDEYIRVWAEYDPGAIGRIHHSEMYEMLRNMEPPVGFGKKCPYRLAYRKLIRMNMPVDENGTVNFTTTLFALIRESLNIKMSTAEYMDIKDMELRQTICKMWPVQAKKKLNLIVPPDSELVFHKMTVGKIYAGYLIVENWRAYKNSQEQG----PRSSPAVSIKSVTK------PVVKEEKSANLLAK 5506 +M + +++ S ++ P Q ST+ ++L + +N IR+ I+EW PFE ++LLTI ANC+ L++ P+ D LE E FL IF VEA LK++A G H AYLRN WN++DF++VV G L +D + D++ LRA RVLRPL+LV+G PSLQVVL SII+AM PLL I LLVLF I I+AIIGLE + G H TC+ N + + +P E PC+ + G G C CK W+GP +GIT+FDN +AMLTVFQCITMEGWTD++Y NDA+G + W+YFV LII+GSFF+LNLVLGVLSGEF+KERE+ + R F KLR +QQ E++ GY++WI +AE++ NE E+K R N S+P E E T+++ G G R R K + + +WR F R R VKS FYW VI LVF NT+ +A EHY Q WLT + A L LF EM++KMY L ++ YF S FN FDC V+ G + E I S G+SVLR +RLLRIFK+TRYW SL NLV SLLNS+RSI SLL LLFLFI+IF+LLGMQLFGG+FNF+E + ++ FD F ++LLTVFQILTGEDWN+VMY+GI + GG G + IYF++L + GNY LLNVFLAIAVDNLA+A+ LT+A++E+ E +R A E+K ++ P V S+ + S ++ ++D N +K P G ++ + P P + ++ K P+ SA FIFS N R CH +VN F I+ I SSI+LAAEDPV+ S +N+IL DY FT +FT+E+ILK+ G LH GS+CR+ +NILD VV +L++F G + +N +K LRVLRVLRPL+ INR LK V CV +++ + NI+IV L QF+FA I VQLF+GK + C+D+SK + C+G + Y P + R W++ F FDN+L AM+ LFTV+T EGWP +L S++S D GPI +YR E++IF+I++ I+ FF +NIFV +I+TFQEQGE E + +LDKNQ+QC+++A+ +PL RY+PK++ +Y+VW +V ST FEY + V+I LNT+ L M++Y Q+ L + + LN FT +F++E +LK++AF PK YF DPWN+FDF+ VIGSI DV++SE +++S +S+ F RLFR RL+KLL +G IR LLWTFI+SF+ALPYV LLI MLFFIY++IGMQVFG I L +INR+NNFQTF +LLLFRCATGE+WQ+IMLAC K C + E +N+ + CGS+F YF+SF LC+FL++NLFVAVIMDNFDYLTRD SILGPHHLDE+ R+WAEYDP A GRI H ++ +LR ++PP+GFGK CP+R+A ++L+ MNMP++ +GTV F TLFAL+R +L IK T ++ + ELR I K+W + K L+ +VPP + ++TVGK YA +LI E +R +K +EQG P A+S+++ + P ++ S +L A+ Sbjct: 64 LMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISIVEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIAYGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCY--NQEGIA-DVPAEDDPSPCA-LETGHG---RQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCITMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGDFQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPR------------------NMSMPTSETESV----NTENVAGGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLTIASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGILETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYGGPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLARTASPEKKQE---------LVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNPETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDTIFTNLILFFILLSSISLAAEDPVQHTSFRNHILGNADYVFTSIFTLEIILKMTAYGAFLHKGSFCRNYFNILDLLVVSVSLISF--------------GIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGEVDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLRRYIPKNQH--QYKVWYVVNSTYFEYLMFVLILLNTICLAMQHY---------------GQSCL-FKIAMNILNMLFTGLFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVILSETNPAEHTQCSPSMNAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRIK--TEGNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGD---DEVTVGKFYATFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAE 1676
BLAST of Voltage dependent L type calcium channel subunit vs. Ensembl Human
Match: CACNA1C (calcium voltage-gated channel subunit alpha1 C [Source:HGNC Symbol;Acc:HGNC:1390]) HSP 1 Score: 1230.31 bits (3182), Expect = 0.000e+0 Identity = 767/1688 (45.44%), Postives = 1042/1688 (61.73%), Query Frame = 2 Query: 599 VMSIDDGSKTTSMRSLAKRTINLSFPGMQTSTS-----KSLFIFSEENVIRKYAKIIIEWGPFEYMVLLTILANCIVLSMERHLPKKDKTLLAGQLELTEKYFLGIFCVEALLKIVALGFCCHKEAYLRNVWNIMDFVVVVTGFLMMFLNIDNHSDSSTV--------DLRTLRAVRVLRPLKLVAGFPSLQVVLKSIIRAMAPLLQIGLLVLFAITIFAIIGLEFYSGAFHYTCFKANSDKLPLPIPTEKSLVPCSNSKNGSGLGAYTCPEDYQCKAYWEGPNYGITSFDNIGYAMLTVFQCITMEGWTDIMYHTNDAIGNRFNWLYFVPLIILGSFFMLNLVLGVLSGXXXXXXXXXXXXXXXLKLRRQQQTEKEFNGYMEWIQKAEEV-LLNEATTTSEDKMRIIAARRRAEKQKYKLLGKNQSIPDFEYEDTELYSETKSMKGNIFIRSYAGIR---RRRKERCTSFWRTEKHF-RFSVRRLVKSQPFYWAVIILVFFNTVCVAIEHYEQGKWLTLFLNYAEYVFLCLFMMEMMIKMYGLSIRVYFQSSFNIFDCVVIAGSLFEIIYGIFVQDSSFGLSVLRALRLLRIFKVTRYWAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXGMQLFGGEFNFEEGKPPQN-FDTFVKALLTVFQILTGEDWNTVMYNGIQSKGGVKERGTVFSIYFVLLVVFGNYTLLNVFLAIAVDNLANXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSSDNFIGRLPLSIDPPMVQVCPPSPQTANSLISKNFSFDHNQVEVNDKGCLLNTNK-PNGKLGMLGHDNTNFNSLESDPVPNKIEPETIQRK--PVLPYSAMFIFSPLNSLRRFCHFVVNLRYFDLFIMIVICASSIALAAEDPVKEKSLKNNILEFFDYAFTGVFTVEMILKIIDLGIILHPGSYCRDLWNILDATVVICALVAFIMGQKPSPTGNKLRGSSAKNLNTIKSLRVLRVLRPLKTINRVPKLKAVFDCVVSSLKNVFNILIVYILFQFIFAVIAVQLFQGKFFYCNDASKSSRETCRGYFFDYAGRST--PETKKRLWQHHDFHFDNILYAMLTLFTVTTGEGWPTVLKNSMESTNIDNGPIADYRQEMAXXXXXXXXXXXXXXXXXXXALIIITFQEQGENELIDLDLDKNQKQCIDFAINEKPLCRYMPKDKTTIKYRVWRLVVSTPFEYFIMVMIALNTLILMMKYYREEKKASSAATHDREQQAYLNYCNTLIFLNSAFTVMFSIECVLKIMAFGPKNYFRDPWNIFDFITVIGSITDVLVSE--------------LQDXXXXXXXXXXXXXXXXXXXXXXQGYTIRILLWTFIQSFKALPYVCLLIAMLFFIYSIIGMQVFGNIKLISEYQINRHNNFQTFTNGLLLLFRCATGESWQEIMLACDNNKPCEKDIENTNNFD----CGSNFTYIYFVSFIFLCSFLMLNLFVAVIMDNFDYLTRDSSILGPHHLDEYIRVWAEYDPGAIGRIHHSEMYEMLRNMEPPVGFGKKCPYRLAYRKLIRMNMPVDENGTVNFTTTLFALIRESLNIKMSTAEYMDIKDMELRQTICKMWPVQAKKKLNLIVPPDSELVFHKMTVGKIYAGYLIVENWRAYKNSQEQG----PRSSPAVSIKSVTK------PVVKEEKSANLLAK 5506 +M + +++ S ++ P Q ST+ ++L + +N IR+ I+EW PFE ++LLTI ANC+ L++ P+ D LE E FL IF VEA LK++A G H AYLRN WN++DF++VV G L +D + D++ LRA RVLRPL+LV+G PSLQVVL SII+AM PLL I LLVLF I I+AIIGLE + G H TC+ N + + +P E PC+ + G G C CK W+GP +GIT+FDN +AMLTVFQCITMEGWTD++Y NDA+G + W+YFV LII+GSFF+LNLVLGVLSGEF+KERE+ + R F KLR +QQ E++ GY++WI +AE++ NE E+K R N S+P E E T+++ G G R R K + + +WR F R R VKS FYW VI LVF NT+ +A EHY Q WLT + A L LF EM++KMY L ++ YF S FN FDC V+ G + E I S G+SVLR +RLLRIFK+TRYW SL NLV SLLNS+RSI SLL LLFLFI+IF+LLGMQLFGG+FNF+E + ++ FD F ++LLTVFQILTGEDWN+VMY+GI + GG G + IYF++L + GNY LLNVFLAIAVDNLA+A+ LT+A++E+ E +R A E+K ++ P V S+ + S ++ ++D N +K P G ++ + P P + ++ K P+ SA FIFS N R CH +VN F I+ I SSI+LAAEDPV+ S +N+IL +FD FT +FT+E+ LK+ G LH GS+CR+ +NILD VV +L++F G + +N +K LRVLRVLRPL+ INR LK V CV +++ + NI+IV L QF+FA I VQLF+GK + C+D+SK + C+G + Y P + R W++ F FDN+L AM+ LFTV+T EGWP +L S++S D GPI +YR E++IF+I++ I+ FF +NIFV +I+TFQEQGE E + +LDKNQ+QC+++A+ +PL RY+PK++ +Y+VW +V ST FEY + V+I LNT+ L M++Y Q+ L + + LN FT +F++E +LK++AF PK YF DPWN+FDF+ VIGSI DV++SE +++S +S+ F RLFR RL+KLL +G IR LLWTFI+SF+ALPYV LLI MLFFIY++IGMQVFG I L +INR+NNFQTF +LLLFRCATGE+WQ+IMLAC K C + E +N+ + CGS+F YF+SF LC+FL++NLFVAVIMDNFDYLTRD SILGPHHLDE+ R+WAEYDP A GRI H ++ +LR ++PP+GFGK CP+R+A ++L+ MNMP++ +GTV F TLFAL+R +L IK T ++ + ELR I K+W + K L+ +VPP + ++TVGK YA +LI E +R +K +EQG P A+S+++ + P ++ S +L A+ Sbjct: 64 LMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISIVEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIAYGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCY--NQEGIA-DVPAEDDPSPCA-LETGHG---RQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCITMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGDFQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPR------------------NMSMPTSETESV----NTENVAGGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLTIASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGILETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYGGPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLARTASPEKKQE---------LVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNPETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDTIFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALKMTAYGAFLHKGSFCRNYFNILDLLVVSVSLISF--------------GIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGEVDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLRRYIPKNQH--QYKVWYVVNSTYFEYLMFVLILLNTICLAMQHY---------------GQSCL-FKIAMNILNMLFTGLFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVILSETNPAEHTQCSPSMNAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRIK--TEGNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGD---DEVTVGKFYATFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAE 1676
BLAST of Voltage dependent L type calcium channel subunit vs. Ensembl Human
Match: CACNA1C (calcium voltage-gated channel subunit alpha1 C [Source:HGNC Symbol;Acc:HGNC:1390]) HSP 1 Score: 1230.31 bits (3182), Expect = 0.000e+0 Identity = 767/1688 (45.44%), Postives = 1042/1688 (61.73%), Query Frame = 2 Query: 599 VMSIDDGSKTTSMRSLAKRTINLSFPGMQTSTS-----KSLFIFSEENVIRKYAKIIIEWGPFEYMVLLTILANCIVLSMERHLPKKDKTLLAGQLELTEKYFLGIFCVEALLKIVALGFCCHKEAYLRNVWNIMDFVVVVTGFLMMFLNIDNHSDSSTV--------DLRTLRAVRVLRPLKLVAGFPSLQVVLKSIIRAMAPLLQIGLLVLFAITIFAIIGLEFYSGAFHYTCFKANSDKLPLPIPTEKSLVPCSNSKNGSGLGAYTCPEDYQCKAYWEGPNYGITSFDNIGYAMLTVFQCITMEGWTDIMYHTNDAIGNRFNWLYFVPLIILGSFFMLNLVLGVLSGXXXXXXXXXXXXXXXLKLRRQQQTEKEFNGYMEWIQKAEEV-LLNEATTTSEDKMRIIAARRRAEKQKYKLLGKNQSIPDFEYEDTELYSETKSMKGNIFIRSYAGIR---RRRKERCTSFWRTEKHF-RFSVRRLVKSQPFYWAVIILVFFNTVCVAIEHYEQGKWLTLFLNYAEYVFLCLFMMEMMIKMYGLSIRVYFQSSFNIFDCVVIAGSLFEIIYGIFVQDSSFGLSVLRALRLLRIFKVTRYWAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXGMQLFGGEFNFEEGKPPQN-FDTFVKALLTVFQILTGEDWNTVMYNGIQSKGGVKERGTVFSIYFVLLVVFGNYTLLNVFLAIAVDNLANXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSSDNFIGRLPLSIDPPMVQVCPPSPQTANSLISKNFSFDHNQVEVNDKGCLLNTNK-PNGKLGMLGHDNTNFNSLESDPVPNKIEPETIQRK--PVLPYSAMFIFSPLNSLRRFCHFVVNLRYFDLFIMIVICASSIALAAEDPVKEKSLKNNILEFFDYAFTGVFTVEMILKIIDLGIILHPGSYCRDLWNILDATVVICALVAFIMGQKPSPTGNKLRGSSAKNLNTIKSLRVLRVLRPLKTINRVPKLKAVFDCVVSSLKNVFNILIVYILFQFIFAVIAVQLFQGKFFYCNDASKSSRETCRGYFFDYAGRST--PETKKRLWQHHDFHFDNILYAMLTLFTVTTGEGWPTVLKNSMESTNIDNGPIADYRQEMAXXXXXXXXXXXXXXXXXXXALIIITFQEQGENELIDLDLDKNQKQCIDFAINEKPLCRYMPKDKTTIKYRVWRLVVSTPFEYFIMVMIALNTLILMMKYYREEKKASSAATHDREQQAYLNYCNTLIFLNSAFTVMFSIECVLKIMAFGPKNYFRDPWNIFDFITVIGSITDVLVSE--------------LQDXXXXXXXXXXXXXXXXXXXXXXQGYTIRILLWTFIQSFKALPYVCLLIAMLFFIYSIIGMQVFGNIKLISEYQINRHNNFQTFTNGLLLLFRCATGESWQEIMLACDNNKPCEKDIENTNNFD----CGSNFTYIYFVSFIFLCSFLMLNLFVAVIMDNFDYLTRDSSILGPHHLDEYIRVWAEYDPGAIGRIHHSEMYEMLRNMEPPVGFGKKCPYRLAYRKLIRMNMPVDENGTVNFTTTLFALIRESLNIKMSTAEYMDIKDMELRQTICKMWPVQAKKKLNLIVPPDSELVFHKMTVGKIYAGYLIVENWRAYKNSQEQG----PRSSPAVSIKSVTK------PVVKEEKSANLLAK 5506 +M + +++ S ++ P Q ST+ ++L + +N IR+ I+EW PFE ++LLTI ANC+ L++ P+ D LE E FL IF VEA LK++A G H AYLRN WN++DF++VV G L +D + D++ LRA RVLRPL+LV+G PSLQVVL SII+AM PLL I LLVLF I I+AIIGLE + G H TC+ N + + +P E PC+ + G G C CK W+GP +GIT+FDN +AMLTVFQCITMEGWTD++Y NDA+G + W+YFV LII+GSFF+LNLVLGVLSGEF+KERE+ + R F KLR +QQ E++ GY++WI +AE++ NE E+K R N S+P E E T+++ G G R R K + + +WR F R R VKS FYW VI LVF NT+ +A EHY Q WLT + A L LF EM++KMY L ++ YF S FN FDC V+ G + E I S G+SVLR +RLLRIFK+TRYW SL NLV SLLNS+RSI SLL LLFLFI+IF+LLGMQLFGG+FNF+E + ++ FD F ++LLTVFQILTGEDWN+VMY+GI + GG G + IYF++L + GNY LLNVFLAIAVDNLA+A+ LT+A++E+ E +R A E+K ++ P V S+ + S ++ ++D N +K P G ++ + P P + ++ K P+ SA FIFS N R CH +VN F I+ I SSI+LAAEDPV+ S +N+IL +FD FT +FT+E+ LK+ G LH GS+CR+ +NILD VV +L++F G + +N +K LRVLRVLRPL+ INR LK V CV +++ + NI+IV L QF+FA I VQLF+GK + C+D+SK + C+G + Y P + R W++ F FDN+L AM+ LFTV+T EGWP +L S++S D GPI +YR E++IF+I++ I+ FF +NIFV +I+TFQEQGE E + +LDKNQ+QC+++A+ +PL RY+PK++ +Y+VW +V ST FEY + V+I LNT+ L M++Y Q+ L + + LN FT +F++E +LK++AF PK YF DPWN+FDF+ VIGSI DV++SE +++S +S+ F RLFR RL+KLL +G IR LLWTFI+SF+ALPYV LLI MLFFIY++IGMQVFG I L +INR+NNFQTF +LLLFRCATGE+WQ+IMLAC K C + E +N+ + CGS+F YF+SF LC+FL++NLFVAVIMDNFDYLTRD SILGPHHLDE+ R+WAEYDP A GRI H ++ +LR ++PP+GFGK CP+R+A ++L+ MNMP++ +GTV F TLFAL+R +L IK T ++ + ELR I K+W + K L+ +VPP + ++TVGK YA +LI E +R +K +EQG P A+S+++ + P ++ S +L A+ Sbjct: 64 LMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISIVEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIAYGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCY--NQEGIA-DVPAEDDPSPCA-LETGHG---RQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCITMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGDFQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPR------------------NMSMPTSETESV----NTENVAGGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLTIASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGILETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYGGPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLARTASPEKKQE---------LVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNPETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDTIFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALKMTAYGAFLHKGSFCRNYFNILDLLVVSVSLISF--------------GIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGEVDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLRRYIPKNQH--QYKVWYVVNSTYFEYLMFVLILLNTICLAMQHY---------------GQSCL-FKIAMNILNMLFTGLFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVILSETNPAEHTQCSPSMNAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRIK--TEGNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGD---DEVTVGKFYATFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAE 1676
BLAST of Voltage dependent L type calcium channel subunit vs. Ensembl Celegans
Match: unc-2 (High voltage activated calcium channel alpha-1 subunit [Source:UniProtKB/TrEMBL;Acc:Q86G45]) HSP 1 Score: 969.533 bits (2505), Expect = 0.000e+0 Identity = 513/788 (65.10%), Postives = 608/788 (77.16%), Query Frame = 2 Query: 3071 KPVLPYSAMFIFSPLNSLRRFCHFVVNLRYFDLFIMIVICASSIALAAEDPVKEKSLKNNILEFFDYAFTGVFTVEMILKIIDLGIILHPGSYCRDLWNILDATVVICALVAFIMGQKPSPTGNKLRGSSAKNLNTIKSLRVLRVLRPLKTINRVPKLKAVFDCVVSSLKNVFNILIVYILFQFIFAVIAVQLFQGKFFYCNDASKSSRETCRGYFFDYAGRS-TPETKKRLWQHHDFHFDNILYAMLTLFTVTTGEGWPTVLKNSMESTNIDNGPIADYRQEMAXXXXXXXXXXXXXXXXXXXALIIITFQEQGENELIDLDLDKNQKQCIDFAINEKPLCRYMPKDKTTIKYRVWRLVVSTPFEYFIMVMIALNTLILMMKYYREEKKASSAATHDREQQAYLNYCNTLIFLNSAFTVMFSIECVLKIMAFGPKNYFRDPWNIFDFITVIGSITDVLVSELQDXXXXXXXXXXXXXXXXXXXXXXQGYTIRILLWTFIQSFKALPYVCLLIAMLFFIYSIIGMQVFGNIKLISEYQINRHNNFQTFTNGLLLLFRCATGESWQEIMLACDNNKPCEKDIENTNNFD----CGSNFTYIYFVSFIFLCSFLMLNLFVAVIMDNFDYLTRDSSILGPHHLDEYIRVWAEYDPGAIGRIHHSEMYEMLRNMEPPVGFGKKCPYRLAYRKLIRMNMPVDENGTVNFTTTLFALIRESLNIKMSTAEYMDIKDMELRQTICKMWPVQAKKKL-NLIVPPDSELVFHKMTVGKIYAGYLIVENWRAYKNSQE 5416 KP++PYS+MF SP N R H +V +YF++ +M VIC SS++LAAEDPV E++ +N +L++ DY FTGVF EM+LK+ID GI+LHPGSYCRD WNILD VV CAL AF GS+ KNLNTIKSLRVLRVLRPLKTI R+PKLKAVFDCVV+SLKNVFNILIVY LFQFIFAVIAVQLF GKFF+C D ++ TC G FF Y ++ P ++R W+ F++DN + AMLTLF VTTGEGWP + +NSM++T D GP +R E+A+FY++FFIVFPFFFVNIFVALIIITFQEQGE EL + DLDKNQKQCIDFA+N +P +MP+DK + KYR+WRLV S PFEYFIM MI NTLILMMKYY L Y L N+A T +F++E +LKI+AFG +NYFRD WN FDF+TV+GSITD LV+E F+SLGFLRLFRAARLI+LL+QGYTIRILLWTF+QSFKALPYVCLLI MLFFIY+I+GMQVFGNI L + +INRHNNFQ+F N ++LLFRCATGE WQ+IM+A K C + NF+ CGSN +Y YF SF+FL SFLMLNLFVAVIMDNFDYLTRDSSILGPHHLDE+IRVWA+YDP A GRIH+SEMYEMLR M PPVGFGKKCPYRLAY+ LIRMNMPV E+GTV+FTTTLFALIRESL+IKM E MD D ELR T+ K+WP++AKK + +L+VPP+ EL F K+TVGKIYAG LI+EN+RA K+ E Sbjct: 970 KPMVPYSSMFFLSPTNPFRVLIHSIVCTKYFEMMVMTVICLSSVSLAAEDPVDEENPRNKVLQYMDYCFTGVFACEMLLKLIDQGILLHPGSYCRDFWNILDGIVVTCALFAFGFA--------GTEGSAGKNLNTIKSLRVLRVLRPLKTIKRIPKLKAVFDCVVNSLKNVFNILIVYFLFQFIFAVIAVQLFNGKFFFCTDKNRKFANTCHGQFFVYDNQNDPPRVEQREWRLRPFNYDNTINAMLTLFVVTTGEGWPGIRQNSMDTTFEDQGPSPFFRVEVALFYVMFFIVFPFFFVNIFVALIIITFQEQGEAELSEGDLDKNQKQCIDFALNARPRSLFMPEDKNSTKYRIWRLVTSPPFEYFIMTMICCNTLILMMKYYNNP----------------LFYEEILRLFNTALTAVFTVESILKILAFGVRNYFRDGWNRFDFVTVVGSITDALVTEF-GGHFVSLGFLRLFRAARLIRLLQQGYTIRILLWTFVQSFKALPYVCLLIGMLFFIYAIVGMQVFGNIWLNAATEINRHNNFQSFFNAVILLFRCATGEGWQDIMMAAVQGKDCARAGSAEINFEKGQTCGSNVSYAYFTSFVFLSSFLMLNLFVAVIMDNFDYLTRDSSILGPHHLDEFIRVWADYDPAATGRIHYSEMYEMLRIMAPPVGFGKKCPYRLAYKHLIRMNMPVAEDGTVHFTTTLFALIRESLSIKMRPVEEMDEADEELRLTLKKIWPLKAKKNMVDLVVPPNHELCFQKLTVGKIYAGLLILENYRARKSGTE 1732 HSP 2 Score: 706.827 bits (1823), Expect = 0.000e+0 Identity = 427/704 (60.65%), Postives = 517/704 (73.44%), Query Frame = 2 Query: 623 KTTSMRSLAKRTINLSFPGMQTSTSKSLFIFSEENVIRKYAKIIIEWGPFEYMVLLTILANCIVLSMERHLPKKDKTLLAGQLELTEKYFLGIFCVEALLKIVALGFCCHKEAYLRNVWNIMDFVVVVTGFLMMF----LNIDNHSDSSTVDLRTLRAVRVLRPLKLVAGFPSLQVVLKSIIRAMAPLLQIGLLVLFAITIFAIIGLEFYSGAFHYTCFKANSDKLPLPIPTEKSLVPCSNSKNGSGLGAYTCP-EDYQCKAYWEGPNYGITSFDNIGYAMLTVFQCITMEGWTDIMYHTNDAIGNRFNWLYFVPLIILGSFFMLNLVLGVLSGXXXXXXXXXXXXXXXLKLRRQQQTEKEFNGYMEWIQKAEEVLLNEATTTSEDKMRIIAARRRAEKQKYKLLGKNQSI--PDFEYEDTELYSETKSMKGNIFIRSYAGIRRRRKERCTSFWRTEKHFRFSVRRLVKSQPFYWAVIILVFFNTVCVAIEHYEQGKWLTLFLNYAEYVFLCLFMMEMMIKMYGLSIRVYFQSSFNIFDCVVIAGSLFEIIYGIFVQDSSFGLSVLRALRLLRIFKVTRYWAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXGMQLFGGEFNFEEGKPPQNFDTFVKALLTVFQILTGEDWNTVMYNGIQSKGGVKERGTVFSIYFVLLVVFGNYTLLNVFLAIAVDNLAN 2713 K S + K T++ + P + S SLFIF+E+N+IR+ AK IIEWGPFEY +LLTI+ NC+VLSME+HLPK DK L+ LE TE YF+GIFC+E +LK++A GF HK +YLR+ WNIMDF+VVV+G + M + +VDLRTLRAVRVLRPLKLV+G PSLQVVLKSI+ AMAPLLQIGLLVLFAI IFAIIGLEFYSGAFH C+ + + +E+ + PC+N S +G Y C + C W GPNYGITSFDNIG+AM+TVFQCITMEGWT +MY+TND++G+ +NW YF+PLI+LGSFFMLNLVLGVLSGEFAKERERVE RR FLKLRRQQQ E+E NGY+EWI AEEV+L E TT E+K I+ ARRRA +K K K QS + ED + E +G +A R+++ C S + K R +R +VK+Q FYW+VI LVF NT CVA EHY Q +W T FL YAE+VFL +F++EM++K++ + R YF S FN FDCVVI GS E+I+ V SFG+SV+RALRLLRIFK+T YW SLRNLV SL+NSMRSIISLLFLLFLFILIFALLGMQLFGG FNF P +FDTF AL+TVFQILTGEDWN VMY I+S+GG+ G +SIYF++LV+FGNYTLLNVFLAIAVDNLAN Sbjct: 206 KAESGTFVRKTTLSSNAPVKEKGPS-SLFIFAEDNIIRRNAKAIIEWGPFEYFILLTIIGNCVVLSMEQHLPKNDKKALSEWLERTEPYFMGIFCLECVLKVIAFGFALHKGSYLRSGWNIMDFIVVVSGVVTMLPFSPATQTANQPVDSVDLRTLRAVRVLRPLKLVSGIPSLQVVLKSILCAMAPLLQIGLLVLFAIIIFAIIGLEFYSGAFHSACYNERGE---IENVSERPM-PCTNKT--SPMGVYNCDVKGTTCLQKWIGPNYGITSFDNIGFAMITVFQCITMEGWTTVMYYTNDSLGSTYNWAYFIPLIVLGSFFMLNLVLGVLSGEFAKERERVENRREFLKLRRQQQIERELNGYLEWILTAEEVILKEDRTTEEEKAAIMEARRRAANKKLKQASKQQSTETEEDFEEDEDEMEEEYVDEGGTVEDEFA--ERKKRGCCHSVGKFIKQLRIQIRIMVKTQIFYWSVITLVFLNTCCVASEHYGQPQWFTDFLKYAEFVFLGIFVVEMLLKLFAMGSRTYFASKFNRFDCVVIVGSAAEVIWAE-VYGGSFGISVMRALRLLRIFKLTSYWVSLRNLVRSLMNSMRSIISLLFLLFLFILIFALLGMQLFGGRFNFPTMHPYTHFDTFPVALITVFQILTGEDWNEVMYLAIESQGGIYSGGWPYSIYFIVLVLFGNYTLLNVFLAIAVDNLAN 899 HSP 3 Score: 116.316 bits (290), Expect = 2.442e-25 Identity = 82/278 (29.50%), Postives = 137/278 (49.28%), Query Frame = 2 Query: 3089 SAMFIFSPLNSLRRFCHFVVNLRYFDLFIMIVICASSIALAAED--PVKEKSLKNNILEFFDYAFTGVFTVEMILKIIDLGIILHPGSYCRDLWNILDATVVICALVAFIMGQKPSPTGNKLRGSSAKNLNTIKSLRVLRVLRPLKTINRVPKLKAVFDCVVSSLKNVFNILIVYILFQFIFAVIAVQLFQGKFFYCNDASKSSRETCRGYFFDYAGRSTPETKK-----------------RLWQHHDF---HFDNILYAMLTLFTVTTGEGWPTVL 3856 S++FIF+ N +RR ++ F+ FI++ I + + L+ E P +K + LE + F G+F +E +LK+I G LH GSY R WNI+D VV+ +V + + T N+ S +++LR +RVLRPLK ++ +P L+ V ++ ++ + I ++ + IFA+I ++ + G F S+ RG + + R P T K + W ++ FDNI +AM+T+F T EGW TV+ Sbjct: 230 SSLFIFAEDNIIRRNAKAIIEWGPFEYFILLTIIGNCVVLSMEQHLPKNDKKALSEWLERTEPYFMGIFCLECVLKVIAFGFALHKGSYLRSGWNIMDFIVVVSGVVTMLPFSPATQTANQPVDSV-----DLRTLRAVRVLRPLKLVSGIPSLQVVLKSILCAMAPLLQIGLLVLFAIIIFAIIGLEFYSGAF-------HSACYNERGEIENVSERPMPCTNKTSPMGVYNCDVKGTTCLQKWIGPNYGITSFDNIGFAMITVFQCITMEGWTTVM 495 HSP 4 Score: 93.2041 bits (230), Expect = 2.343e-18 Identity = 73/274 (26.64%), Postives = 120/274 (43.80%), Query Frame = 2 Query: 701 SLFIFSEENVIRKYAKIIIEWGPFEYMVLLTILANCIVLSMERHLPKKDKTLLAGQLELTEKYFLGIFCVEALLKIVALGFCCHKEAYLRNVWNIMDFVVVVTG-FLMMFLNIDNHSDSSTVDLRTLRAVRVLRPLKLVAGFPSLQVVLKSIIRAMAPLLQIGLLVLFAITIFAIIGLEFYSGAFHYTCFKANSDKLPLPIPTEKSLVPCSNSKNGSGLGAYTCPEDYQCKAYWEGPNYGITSF--DNIGYAMLTVFQCITMEGWTDIMYHTND 1513 S+F S N R I+ FE MV+ I + + L+ E P ++ L+ + F G+F E LLK++ G H +Y R+ WNI+D +VV F F + + + +++LR +RVLRPLK + P L+ V ++ ++ + I ++ IFA+I ++ ++G F + C N K C G + ++ E + + F DN AMLT+F T EGW I ++ D Sbjct: 977 SMFFLSPTNPFRVLIHSIVCTKYFEMMVMTVICLSSVSLAAED--PVDEENPRNKVLQYMDYCFTGVFACEMLLKLIDQGILLHPGSYCRDFWNILDGIVVTCALFAFGFAGTEGSAGKNLNTIKSLRVLRVLRPLKTIKRIPKLKAVFDCVVNSLKNVFNILIVYFLFQFIFAVIAVQLFNGKFFF-CTDKN----------RKFANTCH--------GQFFVYDNQNDPPRVEQREWRLRPFNYDNTINAMLTLFVVTTGEGWPGIRQNSMD 1229 HSP 5 Score: 77.0258 bits (188), Expect = 1.888e-13 Identity = 71/320 (22.19%), Postives = 126/320 (39.38%), Query Frame = 2 Query: 698 KSLFIFSEENVIRKYAKIIIEWGPFEYMVLLTILANCIVLSMERHLPKKDKTLLAGQLELTEKYFLGIFCVEALLKIVALGFCCHKEAYLRNVWNIMDFVVVVTGFLMMFLNIDNHSDSSTVDLRTLRAVRVLRPLKLVAGFPSLQVVLKSIIRAMAPLLQIGLLVLFAITIFAIIGLEFYSGAFHYTCFKANSDKLPLPIPTEKSLVPCSNSKNGSGLGAYTCPEDYQCKAYWEGPNYGITSFDNIGYAMLTVFQCITMEGWTDIM------------------YHTNDAIGNRFNWLYFVPLIILGSFFMLNLVLGVL 1603 +SLF+ ++N + ++ PFEY ++ I N ++L M+ + + L L +F VE++LKI+A G Y R+ WN DFV VV + S LR RA R++R L+ G+ +++++L + +++ L + LL+ I+AI+G++ + + + N +F + A++ +F+C T EGW DIM + G+ ++ YF + L SF MLNL + V+ Sbjct: 1302 RSLFMPEDKNSTKYRIWRLVTSPPFEYFIMTMICCNTLILMMKYY---NNPLFYEEILRLFNTALTAVFTVESILKILAFGV----RNYFRDGWNRFDFVTVVGSITDALVTEFGGHFVSLGFLRLFRAARLIRLLQ--QGY-TIRILLWTFVQSFKALPYVCLLIGMLFFIYAIVGMQVFGNIWLNAATEINRHN----------------------------------------------NFQSFFNAVILLFRCATGEGWQDIMMAAVQGKDCARAGSAEINFEKGQTCGSNVSYAYFTSFVFLSSFLMLNLFVAVI 1565 HSP 6 Score: 75.0998 bits (183), Expect = 6.944e-13 Identity = 66/261 (25.29%), Postives = 128/261 (49.04%), Query Frame = 2 Query: 1982 RFSVRRLVKSQPFYWAVIILVFFNTVCVAIEHYEQGKWLTLFLNYAEYVFLCLFMMEMMIKMYGLSIRVYFQSSFNIFDCVVIAGSLFEIIY----GIFVQDSSFGLSVLRALRLLRIFKVTRYWAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXGMQLFGGEF--NFEEGKPPQNFDTFVKALLTVFQILTGEDWNTVMYNGIQSKGGVK--------ERG-----TVFSIYFVLLVVFGNYTLLNVFLAIAVDNL 2707 ++ + RLV S PF + ++ ++ NT+ + +++Y + L +F +E ++K+ +R YF+ +N FD V + GS+ + + G FV L LR R R+ ++ + ++R L+ + + S +++ + L+ + I+A++GMQ+FG + E NF +F A++ +F+ TGE W +M +Q K + E+G V YF V ++ +LN+F+A+ +DN Sbjct: 1314 KYRIWRLVTSPPFEYFIMTMICCNTLILMMKYYNNPLFYEEILRLFNTALTAVFTVESILKILAFGVRNYFRDGWNRFDFVTVVGSITDALVTEFGGHFV-----SLGFLRLFRAARLIRLLQQGYTIRILLWTFVQSFKALPYVCLLIGMLFFIYAIVGMQVFGNIWLNAATEINRHNNFQSFFNAVILLFRCATGEGWQDIMMAAVQGKDCARAGSAEINFEKGQTCGSNVSYAYFTSFVFLSSFLMLNLFVAVIMDNF 1569 HSP 7 Score: 67.781 bits (164), Expect = 1.315e-10 Identity = 65/283 (22.97%), Postives = 130/283 (45.94%), Query Frame = 2 Query: 4091 CRYMPKDKTTIKYRVWRLVVSTPFEYFIMVMIALNTLILMMKYYREEKKASSAATHDREQQAYLNYCNTLIFLNSAFTVMFSIECVLKIMAFGPKNYFRDPWNIFDFITVIGSITDVLVSELQDXXXXXXXXXXXXXXXXXXXXXXQGYTIRILLWTFIQSFKALPYVCLLIAMLFFIYSIIGMQVFG---NIKLISEYQINRHNNFQTFTNGLLLLFRCATGESWQEIMLACDNNKPCEKDIENTNNFDCGSNFTYIYFVSFIFLCSFLMLNLFVAVIMDNF 4930 C + K ++ ++ +V + F + ++ ++ LNT + ++Y + + + +L Y +FL +F +E +LK+ A G + YF +N FD + ++GS +V+ +E+ SF L ++R L+ + + S +++ + L+ + I++++GMQ+FG N + Y +F TF L+ +F+ TGE W E+M IE+ G IYF+ + ++ +LN+F+A+ +DN Sbjct: 646 CHSVGKFIKQLRIQIRIMVKTQIFYWSVITLVFLNTCCVASEHYGQPQWFTD----------FLKYAE-FVFLG-----IFVVEMLLKLFAMGSRTYFASKFNRFDCVVIVGSAAEVIWAEVYGGSFGISVMRALRLLRIFKLTSYW-VSLRNLVRSLMNSMRSIISLLFLLFLFILIFALLGMQLFGGRFNFPTMHPY-----THFDTFPVALITVFQILTGEDWNEVMYLA---------IESQGGIYSGGWPYSIYFIVLVLFGNYTLLNVFLAIAVDNL 897 HSP 8 Score: 55.4546 bits (132), Expect = 6.479e-7 Identity = 35/102 (34.31%), Postives = 51/102 (50.00%), Query Frame = 2 Query: 4157 PFEYFIMVMIALNTLILMMKYY--REEKKASSAATHDREQQAYLNYCNTLIFLNSAFTVMFSIECVLKIMAFG----PKNYFRDPWNIFDFITVIGSITDVL 4444 PFEYFI++ I N ++L M+ + + +KKA S E F +F +ECVLK++AFG +Y R WNI DFI V+ + +L Sbjct: 253 PFEYFILLTIIGNCVVLSMEQHLPKNDKKALSEWLERTE---------------PYFMGIFCLECVLKVIAFGFALHKGSYLRSGWNIMDFIVVVSGVVTML 339
BLAST of Voltage dependent L type calcium channel subunit vs. Ensembl Celegans
Match: unc-2 (High voltage activated calcium channel alpha-1 subunit [Source:UniProtKB/TrEMBL;Acc:Q86G45]) HSP 1 Score: 969.533 bits (2505), Expect = 0.000e+0 Identity = 552/996 (55.42%), Postives = 673/996 (67.57%), Query Frame = 2 Query: 3071 KPVLPYSAMFIFSPLNSLRRFCHFVVNLRYFDLFIMIVICASSIALAAEDPVKEKSLKNNILEFFDYAFTGVFTVEMILKIIDLGIILHPGSYCRDLWNILDATVVICALVAFIMGQKPSPTGNKLRGSSAKNLNTIKSLRVLRVLRPLKTINRVPKLKAVFDCVVSSLKNVFNILIVYILFQFIFAVIAVQLFQGKFFYCNDASKSSRETCRGYFFDYAGRS-TPETKKRLWQHHDFHFDNILYAMLTLFTVTTGEGWPTVLKNSMESTNIDNGPIADYRQEMAXXXXXXXXXXXXXXXXXXXALIIITFQEQGENELIDLDLDKNQKQCIDFAINEKPLCRYMPKDKTTIKYRVWRLVVSTPFEYFIMVMIALNTLILMMKYYREEKKASSAATHDREQQAYLNYCNTLIFLNSAFTVMFSIECVLKIMAFGPKNYFRDPWNIFDFITVIGSITDVLVSELQDXXXXXXXXXXXXXXXXXXXXXXQGYTIRILLWTFIQSFKALPYVCLLIAMLFFIYSIIGMQVFGNIKLISEYQINRHNNFQTFTNGLLLLFRCATGESWQEIMLACDNNKPCEKDIENTNNFD----CGSNFTYIYFVSFIFLCSFLMLNLFVAVIMDNFDYLTRDSSILGPHHLDEYIRVWAEYDPGAIGRIHHSEMYEMLRNMEPPVGFGKKCPYRLAYRKLIRMNMPVDENGTVNFTTTLFALIRESLNIKMSTAEYMDIKDMELRQTICKMWPVQAKKKL-NLIVPPDSELVFHKMTVGKIYAGYLIVENWRAYKNSQE---------------------QGPRSSPAVSIKSVTKPVVKE----------------------------EKSANLLAKFFVAFKSNTNKSNI------SLDSHHE-------RDEERFS-IDHTYGEDYDANRRYSYLRRGSKPRGSKEIYSDLTPTQDYSYGLRPEHATI----PGMPAPRKFGNRPR----SPMYSLSELETKDR 5827 KP++PYS+MF SP N R H +V +YF++ +M VIC SS++LAAEDPV E++ +N +L++ DY FTGVF EM+LK+ID GI+LHPGSYCRD WNILD VV CAL AF GS+ KNLNTIKSLRVLRVLRPLKTI R+PKLKAVFDCVV+SLKNVFNILIVY LFQFIFAVIAVQLF GKFF+C D ++ TC G FF Y ++ P ++R W+ F++DN + AMLTLF VTTGEGWP + +NSM++T D GP +R E+A+FY++FFIVFPFFFVNIFVALIIITFQEQGE EL + DLDKNQKQCIDFA+N +P +MP+DK + KYR+WRLV S PFEYFIM MI NTLILMMKYY L Y L N+A T +F++E +LKI+AFG +NYFRD WN FDF+TV+GSITD LV+E F+SLGFLRLFRAARLI+LL+QGYTIRILLWTF+QSFKALPYVCLLI MLFFIY+I+GMQVFGNI L + +INRHNNFQ+F N ++LLFRCATGE WQ+IM+A K C + NF+ CGSN +Y YF SF+FL SFLMLNLFVAVIMDNFDYLTRDSSILGPHHLDE+IRVWA+YDP A GRIH+SEMYEMLR M PPVGFGKKCPYRLAY+ LIRMNMPV E+GTV+FTTTLFALIRESL+IKM E MD D ELR T+ K+WP++AKK + +L+VPP+ EL F K+TVGKIYAG LI+EN+RA K+ E + SS T P++ + ++ +L F KS ++ S+D HE R + FS I D++ ++ YS+ S+ RGS+ ++ QD P + ++ P PA R +G+ PR SP S SE + R Sbjct: 848 KPMVPYSSMFFLSPTNPFRVLIHSIVCTKYFEMMVMTVICLSSVSLAAEDPVDEENPRNKVLQYMDYCFTGVFACEMLLKLIDQGILLHPGSYCRDFWNILDGIVVTCALFAFGFA--------GTEGSAGKNLNTIKSLRVLRVLRPLKTIKRIPKLKAVFDCVVNSLKNVFNILIVYFLFQFIFAVIAVQLFNGKFFFCTDKNRKFANTCHGQFFVYDNQNDPPRVEQREWRLRPFNYDNTINAMLTLFVVTTGEGWPGIRQNSMDTTFEDQGPSPFFRVEVALFYVMFFIVFPFFFVNIFVALIIITFQEQGEAELSEGDLDKNQKQCIDFALNARPRSLFMPEDKNSTKYRIWRLVTSPPFEYFIMTMICCNTLILMMKYYNNP----------------LFYEEILRLFNTALTAVFTVESILKILAFGVRNYFRDGWNRFDFVTVVGSITDALVTEF-GGHFVSLGFLRLFRAARLIRLLQQGYTIRILLWTFVQSFKALPYVCLLIGMLFFIYAIVGMQVFGNIWLNAATEINRHNNFQSFFNAVILLFRCATGEGWQDIMMAAVQGKDCARAGSAEINFEKGQTCGSNVSYAYFTSFVFLSSFLMLNLFVAVIMDNFDYLTRDSSILGPHHLDEFIRVWADYDPAATGRIHYSEMYEMLRIMAPPVGFGKKCPYRLAYKHLIRMNMPVAEDGTVHFTTTLFALIRESLSIKMRPVEEMDEADEELRLTLKKIWPLKAKKNMVDLVVPPNHELCFQKLTVGKIYAGLLILENYRARKSGTEVGGQGLFGGGLRSLVAAAKAAESQHSSHTPQPPEETTPIIPQHAQQFSAAPTMSAQGSLQQMQGTSSGGGQRPYSLFNSFVDTIKSGKQDGDVTDVQYQSVDQQHEKMNSTGRRLSDMFSKIRRGTSADHNPHQNYSHRFGYSRNRGSRYDETEHLLAQDNRSPSSPRYRSMARASPPSPAER-YGHPPRYRTESPPSSRSEYQMSIR 1817 HSP 2 Score: 706.442 bits (1822), Expect = 0.000e+0 Identity = 424/702 (60.40%), Postives = 514/702 (73.22%), Query Frame = 2 Query: 623 KTTSMRSLAKRTINLSFPGMQTSTSKSLFIFSEENVIRKYAKIIIEWGPFEYMVLLTILANCIVLSMERHLPKKDKTLLAGQLELTEKYFLGIFCVEALLKIVALGFCCHKEAYLRNVWNIMDFVVVVTGFLMMF----LNIDNHSDSSTVDLRTLRAVRVLRPLKLVAGFPSLQVVLKSIIRAMAPLLQIGLLVLFAITIFAIIGLEFYSGAFHYTCFKANSDKLPLPIPTEKSLVPCSNSKNGSGLGAYTCP-EDYQCKAYWEGPNYGITSFDNIGYAMLTVFQCITMEGWTDIMYHTNDAIGNRFNWLYFVPLIILGSFFMLNLVLGVLSGXXXXXXXXXXXXXXXLKLRRQQQTEKEFNGYMEWIQKAEEVLLNEATTTSEDKMRIIAARRRAEKQKYKLLGKNQSIPDFEYEDTELYSETKSMKGNIFIRSYAGIRRRRKERCTSFWRTEKHFRFSVRRLVKSQPFYWAVIILVFFNTVCVAIEHYEQGKWLTLFLNYAEYVFLCLFMMEMMIKMYGLSIRVYFQSSFNIFDCVVIAGSLFEIIYGIFVQDSSFGLSVLRALRLLRIFKVTRYWAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXGMQLFGGEFNFEEGKPPQNFDTFVKALLTVFQILTGEDWNTVMYNGIQSKGGVKERGTVFSIYFVLLVVFGNYTLLNVFLAIAVDNLAN 2713 K S + K T++ + P + S SLFIF+E+N+IR+ AK IIEWGPFEY +LLTI+ NC+VLSME+HLPK DK L+ LE TE YF+GIFC+E +LK++A GF HK +YLR+ WNIMDF+VVV+G + M + +VDLRTLRAVRVLRPLKLV+G PSLQVVLKSI+ AMAPLLQIGLLVLFAI IFAIIGLEFYSGAFH C+ + + +E+ + PC+N S +G Y C + C W GPNYGITSFDNIG+AM+TVFQCITMEGWT +MY+TND++G+ +NW YF+PLI+LGSFFMLNLVLGVLSGEFAKERERVE RR FLKLRRQQQ E+E NGY+EWI AEEV+L E TT E+K I+ ARRRA +K K K QS TE + + + + R+++ C S + K R +R +VK+Q FYW+VI LVF NT CVA EHY Q +W T FL YAE+VFL +F++EM++K++ + R YF S FN FDCVVI GS E+I+ V SFG+SV+RALRLLRIFK+T YW SLRNLV SL+NSMRSIISLLFLLFLFILIFALLGMQLFGG FNF P +FDTF AL+TVFQILTGEDWN VMY I+S+GG+ G +SIYF++LV+FGNYTLLNVFLAIAVDNLAN Sbjct: 92 KAESGTFVRKTTLSSNAPVKEKGPS-SLFIFAEDNIIRRNAKAIIEWGPFEYFILLTIIGNCVVLSMEQHLPKNDKKALSEWLERTEPYFMGIFCLECVLKVIAFGFALHKGSYLRSGWNIMDFIVVVSGVVTMLPFSPATQTANQPVDSVDLRTLRAVRVLRPLKLVSGIPSLQVVLKSILCAMAPLLQIGLLVLFAIIIFAIIGLEFYSGAFHSACYNERGE---IENVSERPM-PCTNKT--SPMGVYNCDVKGTTCLQKWIGPNYGITSFDNIGFAMITVFQCITMEGWTTVMYYTNDSLGSTYNWAYFIPLIVLGSFFMLNLVLGVLSGEFAKERERVENRREFLKLRRQQQIERELNGYLEWILTAEEVILKEDRTTEEEKAAIMEARRRAANKKLKQASKQQS--------TETEEDFEEDEDEMEEEYVDEAERKKRGCCHSVGKFIKQLRIQIRIMVKTQIFYWSVITLVFLNTCCVASEHYGQPQWFTDFLKYAEFVFLGIFVVEMLLKLFAMGSRTYFASKFNRFDCVVIVGSAAEVIWAE-VYGGSFGISVMRALRLLRIFKLTSYWVSLRNLVRSLMNSMRSIISLLFLLFLFILIFALLGMQLFGGRFNFPTMHPYTHFDTFPVALITVFQILTGEDWNEVMYLAIESQGGIYSGGWPYSIYFIVLVLFGNYTLLNVFLAIAVDNLAN 777 HSP 3 Score: 116.316 bits (290), Expect = 2.247e-25 Identity = 82/278 (29.50%), Postives = 137/278 (49.28%), Query Frame = 2 Query: 3089 SAMFIFSPLNSLRRFCHFVVNLRYFDLFIMIVICASSIALAAED--PVKEKSLKNNILEFFDYAFTGVFTVEMILKIIDLGIILHPGSYCRDLWNILDATVVICALVAFIMGQKPSPTGNKLRGSSAKNLNTIKSLRVLRVLRPLKTINRVPKLKAVFDCVVSSLKNVFNILIVYILFQFIFAVIAVQLFQGKFFYCNDASKSSRETCRGYFFDYAGRSTPETKK-----------------RLWQHHDF---HFDNILYAMLTLFTVTTGEGWPTVL 3856 S++FIF+ N +RR ++ F+ FI++ I + + L+ E P +K + LE + F G+F +E +LK+I G LH GSY R WNI+D VV+ +V + + T N+ S +++LR +RVLRPLK ++ +P L+ V ++ ++ + I ++ + IFA+I ++ + G F S+ RG + + R P T K + W ++ FDNI +AM+T+F T EGW TV+ Sbjct: 116 SSLFIFAEDNIIRRNAKAIIEWGPFEYFILLTIIGNCVVLSMEQHLPKNDKKALSEWLERTEPYFMGIFCLECVLKVIAFGFALHKGSYLRSGWNIMDFIVVVSGVVTMLPFSPATQTANQPVDSV-----DLRTLRAVRVLRPLKLVSGIPSLQVVLKSILCAMAPLLQIGLLVLFAIIIFAIIGLEFYSGAF-------HSACYNERGEIENVSERPMPCTNKTSPMGVYNCDVKGTTCLQKWIGPNYGITSFDNIGFAMITVFQCITMEGWTTVM 381 HSP 4 Score: 93.2041 bits (230), Expect = 2.628e-18 Identity = 73/274 (26.64%), Postives = 120/274 (43.80%), Query Frame = 2 Query: 701 SLFIFSEENVIRKYAKIIIEWGPFEYMVLLTILANCIVLSMERHLPKKDKTLLAGQLELTEKYFLGIFCVEALLKIVALGFCCHKEAYLRNVWNIMDFVVVVTG-FLMMFLNIDNHSDSSTVDLRTLRAVRVLRPLKLVAGFPSLQVVLKSIIRAMAPLLQIGLLVLFAITIFAIIGLEFYSGAFHYTCFKANSDKLPLPIPTEKSLVPCSNSKNGSGLGAYTCPEDYQCKAYWEGPNYGITSF--DNIGYAMLTVFQCITMEGWTDIMYHTND 1513 S+F S N R I+ FE MV+ I + + L+ E P ++ L+ + F G+F E LLK++ G H +Y R+ WNI+D +VV F F + + + +++LR +RVLRPLK + P L+ V ++ ++ + I ++ IFA+I ++ ++G F + C N K C G + ++ E + + F DN AMLT+F T EGW I ++ D Sbjct: 855 SMFFLSPTNPFRVLIHSIVCTKYFEMMVMTVICLSSVSLAAED--PVDEENPRNKVLQYMDYCFTGVFACEMLLKLIDQGILLHPGSYCRDFWNILDGIVVTCALFAFGFAGTEGSAGKNLNTIKSLRVLRVLRPLKTIKRIPKLKAVFDCVVNSLKNVFNILIVYFLFQFIFAVIAVQLFNGKFFF-CTDKN----------RKFANTCH--------GQFFVYDNQNDPPRVEQREWRLRPFNYDNTINAMLTLFVVTTGEGWPGIRQNSMD 1107 HSP 5 Score: 77.0258 bits (188), Expect = 2.122e-13 Identity = 71/320 (22.19%), Postives = 126/320 (39.38%), Query Frame = 2 Query: 698 KSLFIFSEENVIRKYAKIIIEWGPFEYMVLLTILANCIVLSMERHLPKKDKTLLAGQLELTEKYFLGIFCVEALLKIVALGFCCHKEAYLRNVWNIMDFVVVVTGFLMMFLNIDNHSDSSTVDLRTLRAVRVLRPLKLVAGFPSLQVVLKSIIRAMAPLLQIGLLVLFAITIFAIIGLEFYSGAFHYTCFKANSDKLPLPIPTEKSLVPCSNSKNGSGLGAYTCPEDYQCKAYWEGPNYGITSFDNIGYAMLTVFQCITMEGWTDIM------------------YHTNDAIGNRFNWLYFVPLIILGSFFMLNLVLGVL 1603 +SLF+ ++N + ++ PFEY ++ I N ++L M+ + + L L +F VE++LKI+A G Y R+ WN DFV VV + S LR RA R++R L+ G+ +++++L + +++ L + LL+ I+AI+G++ + + + N +F + A++ +F+C T EGW DIM + G+ ++ YF + L SF MLNL + V+ Sbjct: 1180 RSLFMPEDKNSTKYRIWRLVTSPPFEYFIMTMICCNTLILMMKYY---NNPLFYEEILRLFNTALTAVFTVESILKILAFGV----RNYFRDGWNRFDFVTVVGSITDALVTEFGGHFVSLGFLRLFRAARLIRLLQ--QGY-TIRILLWTFVQSFKALPYVCLLIGMLFFIYAIVGMQVFGNIWLNAATEINRHN----------------------------------------------NFQSFFNAVILLFRCATGEGWQDIMMAAVQGKDCARAGSAEINFEKGQTCGSNVSYAYFTSFVFLSSFLMLNLFVAVI 1443 HSP 6 Score: 75.0998 bits (183), Expect = 7.744e-13 Identity = 66/261 (25.29%), Postives = 128/261 (49.04%), Query Frame = 2 Query: 1982 RFSVRRLVKSQPFYWAVIILVFFNTVCVAIEHYEQGKWLTLFLNYAEYVFLCLFMMEMMIKMYGLSIRVYFQSSFNIFDCVVIAGSLFEIIY----GIFVQDSSFGLSVLRALRLLRIFKVTRYWAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXGMQLFGGEF--NFEEGKPPQNFDTFVKALLTVFQILTGEDWNTVMYNGIQSKGGVK--------ERG-----TVFSIYFVLLVVFGNYTLLNVFLAIAVDNL 2707 ++ + RLV S PF + ++ ++ NT+ + +++Y + L +F +E ++K+ +R YF+ +N FD V + GS+ + + G FV L LR R R+ ++ + ++R L+ + + S +++ + L+ + I+A++GMQ+FG + E NF +F A++ +F+ TGE W +M +Q K + E+G V YF V ++ +LN+F+A+ +DN Sbjct: 1192 KYRIWRLVTSPPFEYFIMTMICCNTLILMMKYYNNPLFYEEILRLFNTALTAVFTVESILKILAFGVRNYFRDGWNRFDFVTVVGSITDALVTEFGGHFV-----SLGFLRLFRAARLIRLLQQGYTIRILLWTFVQSFKALPYVCLLIGMLFFIYAIVGMQVFGNIWLNAATEINRHNNFQSFFNAVILLFRCATGEGWQDIMMAAVQGKDCARAGSAEINFEKGQTCGSNVSYAYFTSFVFLSSFLMLNLFVAVIMDNF 1447 HSP 7 Score: 67.781 bits (164), Expect = 1.210e-10 Identity = 65/283 (22.97%), Postives = 130/283 (45.94%), Query Frame = 2 Query: 4091 CRYMPKDKTTIKYRVWRLVVSTPFEYFIMVMIALNTLILMMKYYREEKKASSAATHDREQQAYLNYCNTLIFLNSAFTVMFSIECVLKIMAFGPKNYFRDPWNIFDFITVIGSITDVLVSELQDXXXXXXXXXXXXXXXXXXXXXXQGYTIRILLWTFIQSFKALPYVCLLIAMLFFIYSIIGMQVFG---NIKLISEYQINRHNNFQTFTNGLLLLFRCATGESWQEIMLACDNNKPCEKDIENTNNFDCGSNFTYIYFVSFIFLCSFLMLNLFVAVIMDNF 4930 C + K ++ ++ +V + F + ++ ++ LNT + ++Y + + + +L Y +FL +F +E +LK+ A G + YF +N FD + ++GS +V+ +E+ SF L ++R L+ + + S +++ + L+ + I++++GMQ+FG N + Y +F TF L+ +F+ TGE W E+M IE+ G IYF+ + ++ +LN+F+A+ +DN Sbjct: 524 CHSVGKFIKQLRIQIRIMVKTQIFYWSVITLVFLNTCCVASEHYGQPQWFTD----------FLKYAE-FVFLG-----IFVVEMLLKLFAMGSRTYFASKFNRFDCVVIVGSAAEVIWAEVYGGSFGISVMRALRLLRIFKLTSYW-VSLRNLVRSLMNSMRSIISLLFLLFLFILIFALLGMQLFGGRFNFPTMHPY-----THFDTFPVALITVFQILTGEDWNEVMYLA---------IESQGGIYSGGWPYSIYFIVLVLFGNYTLLNVFLAIAVDNL 775 HSP 8 Score: 55.8398 bits (133), Expect = 5.873e-7 Identity = 35/102 (34.31%), Postives = 51/102 (50.00%), Query Frame = 2 Query: 4157 PFEYFIMVMIALNTLILMMKYY--REEKKASSAATHDREQQAYLNYCNTLIFLNSAFTVMFSIECVLKIMAFG----PKNYFRDPWNIFDFITVIGSITDVL 4444 PFEYFI++ I N ++L M+ + + +KKA S E F +F +ECVLK++AFG +Y R WNI DFI V+ + +L Sbjct: 139 PFEYFILLTIIGNCVVLSMEQHLPKNDKKALSEWLERTE---------------PYFMGIFCLECVLKVIAFGFALHKGSYLRSGWNIMDFIVVVSGVVTML 225
BLAST of Voltage dependent L type calcium channel subunit vs. Ensembl Celegans
Match: unc-2 (High voltage activated calcium channel alpha-1 subunit [Source:UniProtKB/TrEMBL;Acc:Q86G45]) HSP 1 Score: 969.148 bits (2504), Expect = 0.000e+0 Identity = 552/996 (55.42%), Postives = 673/996 (67.57%), Query Frame = 2 Query: 3071 KPVLPYSAMFIFSPLNSLRRFCHFVVNLRYFDLFIMIVICASSIALAAEDPVKEKSLKNNILEFFDYAFTGVFTVEMILKIIDLGIILHPGSYCRDLWNILDATVVICALVAFIMGQKPSPTGNKLRGSSAKNLNTIKSLRVLRVLRPLKTINRVPKLKAVFDCVVSSLKNVFNILIVYILFQFIFAVIAVQLFQGKFFYCNDASKSSRETCRGYFFDYAGRS-TPETKKRLWQHHDFHFDNILYAMLTLFTVTTGEGWPTVLKNSMESTNIDNGPIADYRQEMAXXXXXXXXXXXXXXXXXXXALIIITFQEQGENELIDLDLDKNQKQCIDFAINEKPLCRYMPKDKTTIKYRVWRLVVSTPFEYFIMVMIALNTLILMMKYYREEKKASSAATHDREQQAYLNYCNTLIFLNSAFTVMFSIECVLKIMAFGPKNYFRDPWNIFDFITVIGSITDVLVSELQDXXXXXXXXXXXXXXXXXXXXXXQGYTIRILLWTFIQSFKALPYVCLLIAMLFFIYSIIGMQVFGNIKLISEYQINRHNNFQTFTNGLLLLFRCATGESWQEIMLACDNNKPCEKDIENTNNFD----CGSNFTYIYFVSFIFLCSFLMLNLFVAVIMDNFDYLTRDSSILGPHHLDEYIRVWAEYDPGAIGRIHHSEMYEMLRNMEPPVGFGKKCPYRLAYRKLIRMNMPVDENGTVNFTTTLFALIRESLNIKMSTAEYMDIKDMELRQTICKMWPVQAKKKL-NLIVPPDSELVFHKMTVGKIYAGYLIVENWRAYKNSQE---------------------QGPRSSPAVSIKSVTKPVVKE----------------------------EKSANLLAKFFVAFKSNTNKSNI------SLDSHHE-------RDEERFS-IDHTYGEDYDANRRYSYLRRGSKPRGSKEIYSDLTPTQDYSYGLRPEHATI----PGMPAPRKFGNRPR----SPMYSLSELETKDR 5827 KP++PYS+MF SP N R H +V +YF++ +M VIC SS++LAAEDPV E++ +N +L++ DY FTGVF EM+LK+ID GI+LHPGSYCRD WNILD VV CAL AF GS+ KNLNTIKSLRVLRVLRPLKTI R+PKLKAVFDCVV+SLKNVFNILIVY LFQFIFAVIAVQLF GKFF+C D ++ TC G FF Y ++ P ++R W+ F++DN + AMLTLF VTTGEGWP + +NSM++T D GP +R E+A+FY++FFIVFPFFFVNIFVALIIITFQEQGE EL + DLDKNQKQCIDFA+N +P +MP+DK + KYR+WRLV S PFEYFIM MI NTLILMMKYY L Y L N+A T +F++E +LKI+AFG +NYFRD WN FDF+TV+GSITD LV+E F+SLGFLRLFRAARLI+LL+QGYTIRILLWTF+QSFKALPYVCLLI MLFFIY+I+GMQVFGNI L + +INRHNNFQ+F N ++LLFRCATGE WQ+IM+A K C + NF+ CGSN +Y YF SF+FL SFLMLNLFVAVIMDNFDYLTRDSSILGPHHLDE+IRVWA+YDP A GRIH+SEMYEMLR M PPVGFGKKCPYRLAY+ LIRMNMPV E+GTV+FTTTLFALIRESL+IKM E MD D ELR T+ K+WP++AKK + +L+VPP+ EL F K+TVGKIYAG LI+EN+RA K+ E + SS T P++ + ++ +L F KS ++ S+D HE R + FS I D++ ++ YS+ S+ RGS+ ++ QD P + ++ P PA R +G+ PR SP S SE + R Sbjct: 783 KPMVPYSSMFFLSPTNPFRVLIHSIVCTKYFEMMVMTVICLSSVSLAAEDPVDEENPRNKVLQYMDYCFTGVFACEMLLKLIDQGILLHPGSYCRDFWNILDGIVVTCALFAFGFA--------GTEGSAGKNLNTIKSLRVLRVLRPLKTIKRIPKLKAVFDCVVNSLKNVFNILIVYFLFQFIFAVIAVQLFNGKFFFCTDKNRKFANTCHGQFFVYDNQNDPPRVEQREWRLRPFNYDNTINAMLTLFVVTTGEGWPGIRQNSMDTTFEDQGPSPFFRVEVALFYVMFFIVFPFFFVNIFVALIIITFQEQGEAELSEGDLDKNQKQCIDFALNARPRSLFMPEDKNSTKYRIWRLVTSPPFEYFIMTMICCNTLILMMKYYNNP----------------LFYEEILRLFNTALTAVFTVESILKILAFGVRNYFRDGWNRFDFVTVVGSITDALVTEF-GGHFVSLGFLRLFRAARLIRLLQQGYTIRILLWTFVQSFKALPYVCLLIGMLFFIYAIVGMQVFGNIWLNAATEINRHNNFQSFFNAVILLFRCATGEGWQDIMMAAVQGKDCARAGSAEINFEKGQTCGSNVSYAYFTSFVFLSSFLMLNLFVAVIMDNFDYLTRDSSILGPHHLDEFIRVWADYDPAATGRIHYSEMYEMLRIMAPPVGFGKKCPYRLAYKHLIRMNMPVAEDGTVHFTTTLFALIRESLSIKMRPVEEMDEADEELRLTLKKIWPLKAKKNMVDLVVPPNHELCFQKLTVGKIYAGLLILENYRARKSGTEVGGQGLFGGGLRSLVAAAKAAESQHSSHTPQPPEETTPIIPQHAQQFSAAPTMSAQGSLQQMQGTSSGGGQRPYSLFNSFVDTIKSGKQDGDVTDVQYQSVDQQHEKMNSTGRRLSDMFSKIRRGTSADHNPHQNYSHRFGYSRNRGSRYDETEHLLAQDNRSPSSPRYRSMARASPPSPAER-YGHPPRYRTESPPSSRSEYQMSIR 1752 HSP 2 Score: 706.057 bits (1821), Expect = 0.000e+0 Identity = 424/702 (60.40%), Postives = 514/702 (73.22%), Query Frame = 2 Query: 623 KTTSMRSLAKRTINLSFPGMQTSTSKSLFIFSEENVIRKYAKIIIEWGPFEYMVLLTILANCIVLSMERHLPKKDKTLLAGQLELTEKYFLGIFCVEALLKIVALGFCCHKEAYLRNVWNIMDFVVVVTGFLMMF----LNIDNHSDSSTVDLRTLRAVRVLRPLKLVAGFPSLQVVLKSIIRAMAPLLQIGLLVLFAITIFAIIGLEFYSGAFHYTCFKANSDKLPLPIPTEKSLVPCSNSKNGSGLGAYTCP-EDYQCKAYWEGPNYGITSFDNIGYAMLTVFQCITMEGWTDIMYHTNDAIGNRFNWLYFVPLIILGSFFMLNLVLGVLSGXXXXXXXXXXXXXXXLKLRRQQQTEKEFNGYMEWIQKAEEVLLNEATTTSEDKMRIIAARRRAEKQKYKLLGKNQSIPDFEYEDTELYSETKSMKGNIFIRSYAGIRRRRKERCTSFWRTEKHFRFSVRRLVKSQPFYWAVIILVFFNTVCVAIEHYEQGKWLTLFLNYAEYVFLCLFMMEMMIKMYGLSIRVYFQSSFNIFDCVVIAGSLFEIIYGIFVQDSSFGLSVLRALRLLRIFKVTRYWAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXGMQLFGGEFNFEEGKPPQNFDTFVKALLTVFQILTGEDWNTVMYNGIQSKGGVKERGTVFSIYFVLLVVFGNYTLLNVFLAIAVDNLAN 2713 K S + K T++ + P + S SLFIF+E+N+IR+ AK IIEWGPFEY +LLTI+ NC+VLSME+HLPK DK L+ LE TE YF+GIFC+E +LK++A GF HK +YLR+ WNIMDF+VVV+G + M + +VDLRTLRAVRVLRPLKLV+G PSLQVVLKSI+ AMAPLLQIGLLVLFAI IFAIIGLEFYSGAFH C+ + + +E+ + PC+N S +G Y C + C W GPNYGITSFDNIG+AM+TVFQCITMEGWT +MY+TND++G+ +NW YF+PLI+LGSFFMLNLVLGVLSGEFAKERERVE RR FLKLRRQQQ E+E NGY+EWI AEEV+L E TT E+K I+ ARRRA +K K K QS TE + + + + R+++ C S + K R +R +VK+Q FYW+VI LVF NT CVA EHY Q +W T FL YAE+VFL +F++EM++K++ + R YF S FN FDCVVI GS E+I+ V SFG+SV+RALRLLRIFK+T YW SLRNLV SL+NSMRSIISLLFLLFLFILIFALLGMQLFGG FNF P +FDTF AL+TVFQILTGEDWN VMY I+S+GG+ G +SIYF++LV+FGNYTLLNVFLAIAVDNLAN Sbjct: 27 KAESGTFVRKTTLSSNAPVKEKGPS-SLFIFAEDNIIRRNAKAIIEWGPFEYFILLTIIGNCVVLSMEQHLPKNDKKALSEWLERTEPYFMGIFCLECVLKVIAFGFALHKGSYLRSGWNIMDFIVVVSGVVTMLPFSPATQTANQPVDSVDLRTLRAVRVLRPLKLVSGIPSLQVVLKSILCAMAPLLQIGLLVLFAIIIFAIIGLEFYSGAFHSACYNERGE---IENVSERPM-PCTNKT--SPMGVYNCDVKGTTCLQKWIGPNYGITSFDNIGFAMITVFQCITMEGWTTVMYYTNDSLGSTYNWAYFIPLIVLGSFFMLNLVLGVLSGEFAKERERVENRREFLKLRRQQQIERELNGYLEWILTAEEVILKEDRTTEEEKAAIMEARRRAANKKLKQASKQQS--------TETEEDFEEDEDEMEEEYVDEAERKKRGCCHSVGKFIKQLRIQIRIMVKTQIFYWSVITLVFLNTCCVASEHYGQPQWFTDFLKYAEFVFLGIFVVEMLLKLFAMGSRTYFASKFNRFDCVVIVGSAAEVIWAE-VYGGSFGISVMRALRLLRIFKLTSYWVSLRNLVRSLMNSMRSIISLLFLLFLFILIFALLGMQLFGGRFNFPTMHPYTHFDTFPVALITVFQILTGEDWNEVMYLAIESQGGIYSGGWPYSIYFIVLVLFGNYTLLNVFLAIAVDNLAN 712 HSP 3 Score: 116.316 bits (290), Expect = 2.542e-25 Identity = 82/278 (29.50%), Postives = 137/278 (49.28%), Query Frame = 2 Query: 3089 SAMFIFSPLNSLRRFCHFVVNLRYFDLFIMIVICASSIALAAED--PVKEKSLKNNILEFFDYAFTGVFTVEMILKIIDLGIILHPGSYCRDLWNILDATVVICALVAFIMGQKPSPTGNKLRGSSAKNLNTIKSLRVLRVLRPLKTINRVPKLKAVFDCVVSSLKNVFNILIVYILFQFIFAVIAVQLFQGKFFYCNDASKSSRETCRGYFFDYAGRSTPETKK-----------------RLWQHHDF---HFDNILYAMLTLFTVTTGEGWPTVL 3856 S++FIF+ N +RR ++ F+ FI++ I + + L+ E P +K + LE + F G+F +E +LK+I G LH GSY R WNI+D VV+ +V + + T N+ S +++LR +RVLRPLK ++ +P L+ V ++ ++ + I ++ + IFA+I ++ + G F S+ RG + + R P T K + W ++ FDNI +AM+T+F T EGW TV+ Sbjct: 51 SSLFIFAEDNIIRRNAKAIIEWGPFEYFILLTIIGNCVVLSMEQHLPKNDKKALSEWLERTEPYFMGIFCLECVLKVIAFGFALHKGSYLRSGWNIMDFIVVVSGVVTMLPFSPATQTANQPVDSV-----DLRTLRAVRVLRPLKLVSGIPSLQVVLKSILCAMAPLLQIGLLVLFAIIIFAIIGLEFYSGAF-------HSACYNERGEIENVSERPMPCTNKTSPMGVYNCDVKGTTCLQKWIGPNYGITSFDNIGFAMITVFQCITMEGWTTVM 316 HSP 4 Score: 92.8189 bits (229), Expect = 2.883e-18 Identity = 73/274 (26.64%), Postives = 120/274 (43.80%), Query Frame = 2 Query: 701 SLFIFSEENVIRKYAKIIIEWGPFEYMVLLTILANCIVLSMERHLPKKDKTLLAGQLELTEKYFLGIFCVEALLKIVALGFCCHKEAYLRNVWNIMDFVVVVTG-FLMMFLNIDNHSDSSTVDLRTLRAVRVLRPLKLVAGFPSLQVVLKSIIRAMAPLLQIGLLVLFAITIFAIIGLEFYSGAFHYTCFKANSDKLPLPIPTEKSLVPCSNSKNGSGLGAYTCPEDYQCKAYWEGPNYGITSF--DNIGYAMLTVFQCITMEGWTDIMYHTND 1513 S+F S N R I+ FE MV+ I + + L+ E P ++ L+ + F G+F E LLK++ G H +Y R+ WNI+D +VV F F + + + +++LR +RVLRPLK + P L+ V ++ ++ + I ++ IFA+I ++ ++G F + C N K C G + ++ E + + F DN AMLT+F T EGW I ++ D Sbjct: 790 SMFFLSPTNPFRVLIHSIVCTKYFEMMVMTVICLSSVSLAAED--PVDEENPRNKVLQYMDYCFTGVFACEMLLKLIDQGILLHPGSYCRDFWNILDGIVVTCALFAFGFAGTEGSAGKNLNTIKSLRVLRVLRPLKTIKRIPKLKAVFDCVVNSLKNVFNILIVYFLFQFIFAVIAVQLFNGKFFF-CTDKN----------RKFANTCH--------GQFFVYDNQNDPPRVEQREWRLRPFNYDNTINAMLTLFVVTTGEGWPGIRQNSMD 1042 HSP 5 Score: 76.6406 bits (187), Expect = 2.313e-13 Identity = 71/320 (22.19%), Postives = 126/320 (39.38%), Query Frame = 2 Query: 698 KSLFIFSEENVIRKYAKIIIEWGPFEYMVLLTILANCIVLSMERHLPKKDKTLLAGQLELTEKYFLGIFCVEALLKIVALGFCCHKEAYLRNVWNIMDFVVVVTGFLMMFLNIDNHSDSSTVDLRTLRAVRVLRPLKLVAGFPSLQVVLKSIIRAMAPLLQIGLLVLFAITIFAIIGLEFYSGAFHYTCFKANSDKLPLPIPTEKSLVPCSNSKNGSGLGAYTCPEDYQCKAYWEGPNYGITSFDNIGYAMLTVFQCITMEGWTDIM------------------YHTNDAIGNRFNWLYFVPLIILGSFFMLNLVLGVL 1603 +SLF+ ++N + ++ PFEY ++ I N ++L M+ + + L L +F VE++LKI+A G Y R+ WN DFV VV + S LR RA R++R L+ G+ +++++L + +++ L + LL+ I+AI+G++ + + + N +F + A++ +F+C T EGW DIM + G+ ++ YF + L SF MLNL + V+ Sbjct: 1115 RSLFMPEDKNSTKYRIWRLVTSPPFEYFIMTMICCNTLILMMKYY---NNPLFYEEILRLFNTALTAVFTVESILKILAFGV----RNYFRDGWNRFDFVTVVGSITDALVTEFGGHFVSLGFLRLFRAARLIRLLQ--QGY-TIRILLWTFVQSFKALPYVCLLIGMLFFIYAIVGMQVFGNIWLNAATEINRHN----------------------------------------------NFQSFFNAVILLFRCATGEGWQDIMMAAVQGKDCARAGSAEINFEKGQTCGSNVSYAYFTSFVFLSSFLMLNLFVAVI 1378 HSP 6 Score: 75.0998 bits (183), Expect = 8.658e-13 Identity = 66/261 (25.29%), Postives = 128/261 (49.04%), Query Frame = 2 Query: 1982 RFSVRRLVKSQPFYWAVIILVFFNTVCVAIEHYEQGKWLTLFLNYAEYVFLCLFMMEMMIKMYGLSIRVYFQSSFNIFDCVVIAGSLFEIIY----GIFVQDSSFGLSVLRALRLLRIFKVTRYWAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXGMQLFGGEF--NFEEGKPPQNFDTFVKALLTVFQILTGEDWNTVMYNGIQSKGGVK--------ERG-----TVFSIYFVLLVVFGNYTLLNVFLAIAVDNL 2707 ++ + RLV S PF + ++ ++ NT+ + +++Y + L +F +E ++K+ +R YF+ +N FD V + GS+ + + G FV L LR R R+ ++ + ++R L+ + + S +++ + L+ + I+A++GMQ+FG + E NF +F A++ +F+ TGE W +M +Q K + E+G V YF V ++ +LN+F+A+ +DN Sbjct: 1127 KYRIWRLVTSPPFEYFIMTMICCNTLILMMKYYNNPLFYEEILRLFNTALTAVFTVESILKILAFGVRNYFRDGWNRFDFVTVVGSITDALVTEFGGHFV-----SLGFLRLFRAARLIRLLQQGYTIRILLWTFVQSFKALPYVCLLIGMLFFIYAIVGMQVFGNIWLNAATEINRHNNFQSFFNAVILLFRCATGEGWQDIMMAAVQGKDCARAGSAEINFEKGQTCGSNVSYAYFTSFVFLSSFLMLNLFVAVIMDNF 1382 HSP 7 Score: 67.3958 bits (163), Expect = 1.523e-10 Identity = 65/287 (22.65%), Postives = 132/287 (45.99%), Query Frame = 2 Query: 4079 EKPLCRYMPKDKTTIKYRVWRLVVSTPFEYFIMVMIALNTLILMMKYYREEKKASSAATHDREQQAYLNYCNTLIFLNSAFTVMFSIECVLKIMAFGPKNYFRDPWNIFDFITVIGSITDVLVSELQDXXXXXXXXXXXXXXXXXXXXXXQGYTIRILLWTFIQSFKALPYVCLLIAMLFFIYSIIGMQVFG---NIKLISEYQINRHNNFQTFTNGLLLLFRCATGESWQEIMLACDNNKPCEKDIENTNNFDCGSNFTYIYFVSFIFLCSFLMLNLFVAVIMDNF 4930 ++ C + K ++ ++ +V + F + ++ ++ LNT + ++Y + + + +L Y +FL +F +E +LK+ A G + YF +N FD + ++GS +V+ +E+ SF L ++R L+ + + S +++ + L+ + I++++GMQ+FG N + Y +F TF L+ +F+ TGE W E+M IE+ G IYF+ + ++ +LN+F+A+ +DN Sbjct: 455 KRGCCHSVGKFIKQLRIQIRIMVKTQIFYWSVITLVFLNTCCVASEHYGQPQWFTD----------FLKYAE-FVFLG-----IFVVEMLLKLFAMGSRTYFASKFNRFDCVVIVGSAAEVIWAEVYGGSFGISVMRALRLLRIFKLTSYW-VSLRNLVRSLMNSMRSIISLLFLLFLFILIFALLGMQLFGGRFNFPTMHPY-----THFDTFPVALITVFQILTGEDWNEVMYLA---------IESQGGIYSGGWPYSIYFIVLVLFGNYTLLNVFLAIAVDNL 710 HSP 8 Score: 55.8398 bits (133), Expect = 6.050e-7 Identity = 35/102 (34.31%), Postives = 51/102 (50.00%), Query Frame = 2 Query: 4157 PFEYFIMVMIALNTLILMMKYY--REEKKASSAATHDREQQAYLNYCNTLIFLNSAFTVMFSIECVLKIMAFG----PKNYFRDPWNIFDFITVIGSITDVL 4444 PFEYFI++ I N ++L M+ + + +KKA S E F +F +ECVLK++AFG +Y R WNI DFI V+ + +L Sbjct: 74 PFEYFILLTIIGNCVVLSMEQHLPKNDKKALSEWLERTE---------------PYFMGIFCLECVLKVIAFGFALHKGSYLRSGWNIMDFIVVVSGVVTML 160
BLAST of Voltage dependent L type calcium channel subunit vs. Ensembl Celegans
Match: unc-2 (High voltage activated calcium channel alpha-1 subunit [Source:UniProtKB/TrEMBL;Acc:Q86G45]) HSP 1 Score: 969.148 bits (2504), Expect = 0.000e+0 Identity = 552/996 (55.42%), Postives = 673/996 (67.57%), Query Frame = 2 Query: 3071 KPVLPYSAMFIFSPLNSLRRFCHFVVNLRYFDLFIMIVICASSIALAAEDPVKEKSLKNNILEFFDYAFTGVFTVEMILKIIDLGIILHPGSYCRDLWNILDATVVICALVAFIMGQKPSPTGNKLRGSSAKNLNTIKSLRVLRVLRPLKTINRVPKLKAVFDCVVSSLKNVFNILIVYILFQFIFAVIAVQLFQGKFFYCNDASKSSRETCRGYFFDYAGRS-TPETKKRLWQHHDFHFDNILYAMLTLFTVTTGEGWPTVLKNSMESTNIDNGPIADYRQEMAXXXXXXXXXXXXXXXXXXXALIIITFQEQGENELIDLDLDKNQKQCIDFAINEKPLCRYMPKDKTTIKYRVWRLVVSTPFEYFIMVMIALNTLILMMKYYREEKKASSAATHDREQQAYLNYCNTLIFLNSAFTVMFSIECVLKIMAFGPKNYFRDPWNIFDFITVIGSITDVLVSELQDXXXXXXXXXXXXXXXXXXXXXXQGYTIRILLWTFIQSFKALPYVCLLIAMLFFIYSIIGMQVFGNIKLISEYQINRHNNFQTFTNGLLLLFRCATGESWQEIMLACDNNKPCEKDIENTNNFD----CGSNFTYIYFVSFIFLCSFLMLNLFVAVIMDNFDYLTRDSSILGPHHLDEYIRVWAEYDPGAIGRIHHSEMYEMLRNMEPPVGFGKKCPYRLAYRKLIRMNMPVDENGTVNFTTTLFALIRESLNIKMSTAEYMDIKDMELRQTICKMWPVQAKKKL-NLIVPPDSELVFHKMTVGKIYAGYLIVENWRAYKNSQE---------------------QGPRSSPAVSIKSVTKPVVKE----------------------------EKSANLLAKFFVAFKSNTNKSNI------SLDSHHE-------RDEERFS-IDHTYGEDYDANRRYSYLRRGSKPRGSKEIYSDLTPTQDYSYGLRPEHATI----PGMPAPRKFGNRPR----SPMYSLSELETKDR 5827 KP++PYS+MF SP N R H +V +YF++ +M VIC SS++LAAEDPV E++ +N +L++ DY FTGVF EM+LK+ID GI+LHPGSYCRD WNILD VV CAL AF GS+ KNLNTIKSLRVLRVLRPLKTI R+PKLKAVFDCVV+SLKNVFNILIVY LFQFIFAVIAVQLF GKFF+C D ++ TC G FF Y ++ P ++R W+ F++DN + AMLTLF VTTGEGWP + +NSM++T D GP +R E+A+FY++FFIVFPFFFVNIFVALIIITFQEQGE EL + DLDKNQKQCIDFA+N +P +MP+DK + KYR+WRLV S PFEYFIM MI NTLILMMKYY L Y L N+A T +F++E +LKI+AFG +NYFRD WN FDF+TV+GSITD LV+E F+SLGFLRLFRAARLI+LL+QGYTIRILLWTF+QSFKALPYVCLLI MLFFIY+I+GMQVFGNI L + +INRHNNFQ+F N ++LLFRCATGE WQ+IM+A K C + NF+ CGSN +Y YF SF+FL SFLMLNLFVAVIMDNFDYLTRDSSILGPHHLDE+IRVWA+YDP A GRIH+SEMYEMLR M PPVGFGKKCPYRLAY+ LIRMNMPV E+GTV+FTTTLFALIRESL+IKM E MD D ELR T+ K+WP++AKK + +L+VPP+ EL F K+TVGKIYAG LI+EN+RA K+ E + SS T P++ + ++ +L F KS ++ S+D HE R + FS I D++ ++ YS+ S+ RGS+ ++ QD P + ++ P PA R +G+ PR SP S SE + R Sbjct: 848 KPMVPYSSMFFLSPTNPFRVLIHSIVCTKYFEMMVMTVICLSSVSLAAEDPVDEENPRNKVLQYMDYCFTGVFACEMLLKLIDQGILLHPGSYCRDFWNILDGIVVTCALFAFGFA--------GTEGSAGKNLNTIKSLRVLRVLRPLKTIKRIPKLKAVFDCVVNSLKNVFNILIVYFLFQFIFAVIAVQLFNGKFFFCTDKNRKFANTCHGQFFVYDNQNDPPRVEQREWRLRPFNYDNTINAMLTLFVVTTGEGWPGIRQNSMDTTFEDQGPSPFFRVEVALFYVMFFIVFPFFFVNIFVALIIITFQEQGEAELSEGDLDKNQKQCIDFALNARPRSLFMPEDKNSTKYRIWRLVTSPPFEYFIMTMICCNTLILMMKYYNNP----------------LFYEEILRLFNTALTAVFTVESILKILAFGVRNYFRDGWNRFDFVTVVGSITDALVTEF-GGHFVSLGFLRLFRAARLIRLLQQGYTIRILLWTFVQSFKALPYVCLLIGMLFFIYAIVGMQVFGNIWLNAATEINRHNNFQSFFNAVILLFRCATGEGWQDIMMAAVQGKDCARAGSAEINFEKGQTCGSNVSYAYFTSFVFLSSFLMLNLFVAVIMDNFDYLTRDSSILGPHHLDEFIRVWADYDPAATGRIHYSEMYEMLRIMAPPVGFGKKCPYRLAYKHLIRMNMPVAEDGTVHFTTTLFALIRESLSIKMRPVEEMDEADEELRLTLKKIWPLKAKKNMVDLVVPPNHELCFQKLTVGKIYAGLLILENYRARKSGTEVGGQGLFGGGLRSLVAAAKAAESQHSSHTPQPPEETTPIIPQHAQQFSAAPTMSAQGSLQQMQGTSSGGGQRPYSLFNSFVDTIKSGKQDGDVTDVQYQSVDQQHEKMNSTGRRLSDMFSKIRRGTSADHNPHQNYSHRFGYSRNRGSRYDETEHLLAQDNRSPSSPRYRSMARASPPSPAER-YGHPPRYRTESPPSSRSEYQMSIR 1817 HSP 2 Score: 706.442 bits (1822), Expect = 0.000e+0 Identity = 424/702 (60.40%), Postives = 514/702 (73.22%), Query Frame = 2 Query: 623 KTTSMRSLAKRTINLSFPGMQTSTSKSLFIFSEENVIRKYAKIIIEWGPFEYMVLLTILANCIVLSMERHLPKKDKTLLAGQLELTEKYFLGIFCVEALLKIVALGFCCHKEAYLRNVWNIMDFVVVVTGFLMMF----LNIDNHSDSSTVDLRTLRAVRVLRPLKLVAGFPSLQVVLKSIIRAMAPLLQIGLLVLFAITIFAIIGLEFYSGAFHYTCFKANSDKLPLPIPTEKSLVPCSNSKNGSGLGAYTCP-EDYQCKAYWEGPNYGITSFDNIGYAMLTVFQCITMEGWTDIMYHTNDAIGNRFNWLYFVPLIILGSFFMLNLVLGVLSGXXXXXXXXXXXXXXXLKLRRQQQTEKEFNGYMEWIQKAEEVLLNEATTTSEDKMRIIAARRRAEKQKYKLLGKNQSIPDFEYEDTELYSETKSMKGNIFIRSYAGIRRRRKERCTSFWRTEKHFRFSVRRLVKSQPFYWAVIILVFFNTVCVAIEHYEQGKWLTLFLNYAEYVFLCLFMMEMMIKMYGLSIRVYFQSSFNIFDCVVIAGSLFEIIYGIFVQDSSFGLSVLRALRLLRIFKVTRYWAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXGMQLFGGEFNFEEGKPPQNFDTFVKALLTVFQILTGEDWNTVMYNGIQSKGGVKERGTVFSIYFVLLVVFGNYTLLNVFLAIAVDNLAN 2713 K S + K T++ + P + S SLFIF+E+N+IR+ AK IIEWGPFEY +LLTI+ NC+VLSME+HLPK DK L+ LE TE YF+GIFC+E +LK++A GF HK +YLR+ WNIMDF+VVV+G + M + +VDLRTLRAVRVLRPLKLV+G PSLQVVLKSI+ AMAPLLQIGLLVLFAI IFAIIGLEFYSGAFH C+ + + +E+ + PC+N S +G Y C + C W GPNYGITSFDNIG+AM+TVFQCITMEGWT +MY+TND++G+ +NW YF+PLI+LGSFFMLNLVLGVLSGEFAKERERVE RR FLKLRRQQQ E+E NGY+EWI AEEV+L E TT E+K I+ ARRRA +K K K QS TE + + + + R+++ C S + K R +R +VK+Q FYW+VI LVF NT CVA EHY Q +W T FL YAE+VFL +F++EM++K++ + R YF S FN FDCVVI GS E+I+ V SFG+SV+RALRLLRIFK+T YW SLRNLV SL+NSMRSIISLLFLLFLFILIFALLGMQLFGG FNF P +FDTF AL+TVFQILTGEDWN VMY I+S+GG+ G +SIYF++LV+FGNYTLLNVFLAIAVDNLAN Sbjct: 92 KAESGTFVRKTTLSSNAPVKEKGPS-SLFIFAEDNIIRRNAKAIIEWGPFEYFILLTIIGNCVVLSMEQHLPKNDKKALSEWLERTEPYFMGIFCLECVLKVIAFGFALHKGSYLRSGWNIMDFIVVVSGVVTMLPFSPATQTANQPVDSVDLRTLRAVRVLRPLKLVSGIPSLQVVLKSILCAMAPLLQIGLLVLFAIIIFAIIGLEFYSGAFHSACYNERGE---IENVSERPM-PCTNKT--SPMGVYNCDVKGTTCLQKWIGPNYGITSFDNIGFAMITVFQCITMEGWTTVMYYTNDSLGSTYNWAYFIPLIVLGSFFMLNLVLGVLSGEFAKERERVENRREFLKLRRQQQIERELNGYLEWILTAEEVILKEDRTTEEEKAAIMEARRRAANKKLKQASKQQS--------TETEEDFEEDEDEMEEEYVDEAERKKRGCCHSVGKFIKQLRIQIRIMVKTQIFYWSVITLVFLNTCCVASEHYGQPQWFTDFLKYAEFVFLGIFVVEMLLKLFAMGSRTYFASKFNRFDCVVIVGSAAEVIWAE-VYGGSFGISVMRALRLLRIFKLTSYWVSLRNLVRSLMNSMRSIISLLFLLFLFILIFALLGMQLFGGRFNFPTMHPYTHFDTFPVALITVFQILTGEDWNEVMYLAIESQGGIYSGGWPYSIYFIVLVLFGNYTLLNVFLAIAVDNLAN 777 HSP 3 Score: 116.316 bits (290), Expect = 2.227e-25 Identity = 82/278 (29.50%), Postives = 137/278 (49.28%), Query Frame = 2 Query: 3089 SAMFIFSPLNSLRRFCHFVVNLRYFDLFIMIVICASSIALAAED--PVKEKSLKNNILEFFDYAFTGVFTVEMILKIIDLGIILHPGSYCRDLWNILDATVVICALVAFIMGQKPSPTGNKLRGSSAKNLNTIKSLRVLRVLRPLKTINRVPKLKAVFDCVVSSLKNVFNILIVYILFQFIFAVIAVQLFQGKFFYCNDASKSSRETCRGYFFDYAGRSTPETKK-----------------RLWQHHDF---HFDNILYAMLTLFTVTTGEGWPTVL 3856 S++FIF+ N +RR ++ F+ FI++ I + + L+ E P +K + LE + F G+F +E +LK+I G LH GSY R WNI+D VV+ +V + + T N+ S +++LR +RVLRPLK ++ +P L+ V ++ ++ + I ++ + IFA+I ++ + G F S+ RG + + R P T K + W ++ FDNI +AM+T+F T EGW TV+ Sbjct: 116 SSLFIFAEDNIIRRNAKAIIEWGPFEYFILLTIIGNCVVLSMEQHLPKNDKKALSEWLERTEPYFMGIFCLECVLKVIAFGFALHKGSYLRSGWNIMDFIVVVSGVVTMLPFSPATQTANQPVDSV-----DLRTLRAVRVLRPLKLVSGIPSLQVVLKSILCAMAPLLQIGLLVLFAIIIFAIIGLEFYSGAF-------HSACYNERGEIENVSERPMPCTNKTSPMGVYNCDVKGTTCLQKWIGPNYGITSFDNIGFAMITVFQCITMEGWTTVM 381 HSP 4 Score: 93.2041 bits (230), Expect = 2.694e-18 Identity = 73/274 (26.64%), Postives = 120/274 (43.80%), Query Frame = 2 Query: 701 SLFIFSEENVIRKYAKIIIEWGPFEYMVLLTILANCIVLSMERHLPKKDKTLLAGQLELTEKYFLGIFCVEALLKIVALGFCCHKEAYLRNVWNIMDFVVVVTG-FLMMFLNIDNHSDSSTVDLRTLRAVRVLRPLKLVAGFPSLQVVLKSIIRAMAPLLQIGLLVLFAITIFAIIGLEFYSGAFHYTCFKANSDKLPLPIPTEKSLVPCSNSKNGSGLGAYTCPEDYQCKAYWEGPNYGITSF--DNIGYAMLTVFQCITMEGWTDIMYHTND 1513 S+F S N R I+ FE MV+ I + + L+ E P ++ L+ + F G+F E LLK++ G H +Y R+ WNI+D +VV F F + + + +++LR +RVLRPLK + P L+ V ++ ++ + I ++ IFA+I ++ ++G F + C N K C G + ++ E + + F DN AMLT+F T EGW I ++ D Sbjct: 855 SMFFLSPTNPFRVLIHSIVCTKYFEMMVMTVICLSSVSLAAED--PVDEENPRNKVLQYMDYCFTGVFACEMLLKLIDQGILLHPGSYCRDFWNILDGIVVTCALFAFGFAGTEGSAGKNLNTIKSLRVLRVLRPLKTIKRIPKLKAVFDCVVNSLKNVFNILIVYFLFQFIFAVIAVQLFNGKFFF-CTDKN----------RKFANTCH--------GQFFVYDNQNDPPRVEQREWRLRPFNYDNTINAMLTLFVVTTGEGWPGIRQNSMD 1107 HSP 5 Score: 77.0258 bits (188), Expect = 2.289e-13 Identity = 71/320 (22.19%), Postives = 126/320 (39.38%), Query Frame = 2 Query: 698 KSLFIFSEENVIRKYAKIIIEWGPFEYMVLLTILANCIVLSMERHLPKKDKTLLAGQLELTEKYFLGIFCVEALLKIVALGFCCHKEAYLRNVWNIMDFVVVVTGFLMMFLNIDNHSDSSTVDLRTLRAVRVLRPLKLVAGFPSLQVVLKSIIRAMAPLLQIGLLVLFAITIFAIIGLEFYSGAFHYTCFKANSDKLPLPIPTEKSLVPCSNSKNGSGLGAYTCPEDYQCKAYWEGPNYGITSFDNIGYAMLTVFQCITMEGWTDIM------------------YHTNDAIGNRFNWLYFVPLIILGSFFMLNLVLGVL 1603 +SLF+ ++N + ++ PFEY ++ I N ++L M+ + + L L +F VE++LKI+A G Y R+ WN DFV VV + S LR RA R++R L+ G+ +++++L + +++ L + LL+ I+AI+G++ + + + N +F + A++ +F+C T EGW DIM + G+ ++ YF + L SF MLNL + V+ Sbjct: 1180 RSLFMPEDKNSTKYRIWRLVTSPPFEYFIMTMICCNTLILMMKYY---NNPLFYEEILRLFNTALTAVFTVESILKILAFGV----RNYFRDGWNRFDFVTVVGSITDALVTEFGGHFVSLGFLRLFRAARLIRLLQ--QGY-TIRILLWTFVQSFKALPYVCLLIGMLFFIYAIVGMQVFGNIWLNAATEINRHN----------------------------------------------NFQSFFNAVILLFRCATGEGWQDIMMAAVQGKDCARAGSAEINFEKGQTCGSNVSYAYFTSFVFLSSFLMLNLFVAVI 1443 HSP 6 Score: 75.0998 bits (183), Expect = 7.940e-13 Identity = 66/261 (25.29%), Postives = 128/261 (49.04%), Query Frame = 2 Query: 1982 RFSVRRLVKSQPFYWAVIILVFFNTVCVAIEHYEQGKWLTLFLNYAEYVFLCLFMMEMMIKMYGLSIRVYFQSSFNIFDCVVIAGSLFEIIY----GIFVQDSSFGLSVLRALRLLRIFKVTRYWAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXGMQLFGGEF--NFEEGKPPQNFDTFVKALLTVFQILTGEDWNTVMYNGIQSKGGVK--------ERG-----TVFSIYFVLLVVFGNYTLLNVFLAIAVDNL 2707 ++ + RLV S PF + ++ ++ NT+ + +++Y + L +F +E ++K+ +R YF+ +N FD V + GS+ + + G FV L LR R R+ ++ + ++R L+ + + S +++ + L+ + I+A++GMQ+FG + E NF +F A++ +F+ TGE W +M +Q K + E+G V YF V ++ +LN+F+A+ +DN Sbjct: 1192 KYRIWRLVTSPPFEYFIMTMICCNTLILMMKYYNNPLFYEEILRLFNTALTAVFTVESILKILAFGVRNYFRDGWNRFDFVTVVGSITDALVTEFGGHFV-----SLGFLRLFRAARLIRLLQQGYTIRILLWTFVQSFKALPYVCLLIGMLFFIYAIVGMQVFGNIWLNAATEINRHNNFQSFFNAVILLFRCATGEGWQDIMMAAVQGKDCARAGSAEINFEKGQTCGSNVSYAYFTSFVFLSSFLMLNLFVAVIMDNF 1447 HSP 7 Score: 67.781 bits (164), Expect = 1.272e-10 Identity = 65/283 (22.97%), Postives = 130/283 (45.94%), Query Frame = 2 Query: 4091 CRYMPKDKTTIKYRVWRLVVSTPFEYFIMVMIALNTLILMMKYYREEKKASSAATHDREQQAYLNYCNTLIFLNSAFTVMFSIECVLKIMAFGPKNYFRDPWNIFDFITVIGSITDVLVSELQDXXXXXXXXXXXXXXXXXXXXXXQGYTIRILLWTFIQSFKALPYVCLLIAMLFFIYSIIGMQVFG---NIKLISEYQINRHNNFQTFTNGLLLLFRCATGESWQEIMLACDNNKPCEKDIENTNNFDCGSNFTYIYFVSFIFLCSFLMLNLFVAVIMDNF 4930 C + K ++ ++ +V + F + ++ ++ LNT + ++Y + + + +L Y +FL +F +E +LK+ A G + YF +N FD + ++GS +V+ +E+ SF L ++R L+ + + S +++ + L+ + I++++GMQ+FG N + Y +F TF L+ +F+ TGE W E+M IE+ G IYF+ + ++ +LN+F+A+ +DN Sbjct: 524 CHSVGKFIKQLRIQIRIMVKTQIFYWSVITLVFLNTCCVASEHYGQPQWFTD----------FLKYAE-FVFLG-----IFVVEMLLKLFAMGSRTYFASKFNRFDCVVIVGSAAEVIWAEVYGGSFGISVMRALRLLRIFKLTSYW-VSLRNLVRSLMNSMRSIISLLFLLFLFILIFALLGMQLFGGRFNFPTMHPY-----THFDTFPVALITVFQILTGEDWNEVMYLA---------IESQGGIYSGGWPYSIYFIVLVLFGNYTLLNVFLAIAVDNL 775 HSP 8 Score: 55.8398 bits (133), Expect = 6.073e-7 Identity = 35/102 (34.31%), Postives = 51/102 (50.00%), Query Frame = 2 Query: 4157 PFEYFIMVMIALNTLILMMKYY--REEKKASSAATHDREQQAYLNYCNTLIFLNSAFTVMFSIECVLKIMAFG----PKNYFRDPWNIFDFITVIGSITDVL 4444 PFEYFI++ I N ++L M+ + + +KKA S E F +F +ECVLK++AFG +Y R WNI DFI V+ + +L Sbjct: 139 PFEYFILLTIIGNCVVLSMEQHLPKNDKKALSEWLERTE---------------PYFMGIFCLECVLKVIAFGFALHKGSYLRSGWNIMDFIVVVSGVVTML 225
BLAST of Voltage dependent L type calcium channel subunit vs. Ensembl Celegans
Match: unc-2 (High voltage activated calcium channel alpha-1 subunit [Source:UniProtKB/TrEMBL;Acc:Q86G45]) HSP 1 Score: 968.763 bits (2503), Expect = 0.000e+0 Identity = 513/788 (65.10%), Postives = 608/788 (77.16%), Query Frame = 2 Query: 3071 KPVLPYSAMFIFSPLNSLRRFCHFVVNLRYFDLFIMIVICASSIALAAEDPVKEKSLKNNILEFFDYAFTGVFTVEMILKIIDLGIILHPGSYCRDLWNILDATVVICALVAFIMGQKPSPTGNKLRGSSAKNLNTIKSLRVLRVLRPLKTINRVPKLKAVFDCVVSSLKNVFNILIVYILFQFIFAVIAVQLFQGKFFYCNDASKSSRETCRGYFFDYAGRS-TPETKKRLWQHHDFHFDNILYAMLTLFTVTTGEGWPTVLKNSMESTNIDNGPIADYRQEMAXXXXXXXXXXXXXXXXXXXALIIITFQEQGENELIDLDLDKNQKQCIDFAINEKPLCRYMPKDKTTIKYRVWRLVVSTPFEYFIMVMIALNTLILMMKYYREEKKASSAATHDREQQAYLNYCNTLIFLNSAFTVMFSIECVLKIMAFGPKNYFRDPWNIFDFITVIGSITDVLVSELQDXXXXXXXXXXXXXXXXXXXXXXQGYTIRILLWTFIQSFKALPYVCLLIAMLFFIYSIIGMQVFGNIKLISEYQINRHNNFQTFTNGLLLLFRCATGESWQEIMLACDNNKPCEKDIENTNNFD----CGSNFTYIYFVSFIFLCSFLMLNLFVAVIMDNFDYLTRDSSILGPHHLDEYIRVWAEYDPGAIGRIHHSEMYEMLRNMEPPVGFGKKCPYRLAYRKLIRMNMPVDENGTVNFTTTLFALIRESLNIKMSTAEYMDIKDMELRQTICKMWPVQAKKKL-NLIVPPDSELVFHKMTVGKIYAGYLIVENWRAYKNSQE 5416 KP++PYS+MF SP N R H +V +YF++ +M VIC SS++LAAEDPV E++ +N +L++ DY FTGVF EM+LK+ID GI+LHPGSYCRD WNILD VV CAL AF GS+ KNLNTIKSLRVLRVLRPLKTI R+PKLKAVFDCVV+SLKNVFNILIVY LFQFIFAVIAVQLF GKFF+C D ++ TC G FF Y ++ P ++R W+ F++DN + AMLTLF VTTGEGWP + +NSM++T D GP +R E+A+FY++FFIVFPFFFVNIFVALIIITFQEQGE EL + DLDKNQKQCIDFA+N +P +MP+DK + KYR+WRLV S PFEYFIM MI NTLILMMKYY L Y L N+A T +F++E +LKI+AFG +NYFRD WN FDF+TV+GSITD LV+E F+SLGFLRLFRAARLI+LL+QGYTIRILLWTF+QSFKALPYVCLLI MLFFIY+I+GMQVFGNI L + +INRHNNFQ+F N ++LLFRCATGE WQ+IM+A K C + NF+ CGSN +Y YF SF+FL SFLMLNLFVAVIMDNFDYLTRDSSILGPHHLDE+IRVWA+YDP A GRIH+SEMYEMLR M PPVGFGKKCPYRLAY+ LIRMNMPV E+GTV+FTTTLFALIRESL+IKM E MD D ELR T+ K+WP++AKK + +L+VPP+ EL F K+TVGKIYAG LI+EN+RA K+ E Sbjct: 918 KPMVPYSSMFFLSPTNPFRVLIHSIVCTKYFEMMVMTVICLSSVSLAAEDPVDEENPRNKVLQYMDYCFTGVFACEMLLKLIDQGILLHPGSYCRDFWNILDGIVVTCALFAFGFA--------GTEGSAGKNLNTIKSLRVLRVLRPLKTIKRIPKLKAVFDCVVNSLKNVFNILIVYFLFQFIFAVIAVQLFNGKFFFCTDKNRKFANTCHGQFFVYDNQNDPPRVEQREWRLRPFNYDNTINAMLTLFVVTTGEGWPGIRQNSMDTTFEDQGPSPFFRVEVALFYVMFFIVFPFFFVNIFVALIIITFQEQGEAELSEGDLDKNQKQCIDFALNARPRSLFMPEDKNSTKYRIWRLVTSPPFEYFIMTMICCNTLILMMKYYNNP----------------LFYEEILRLFNTALTAVFTVESILKILAFGVRNYFRDGWNRFDFVTVVGSITDALVTEF-GGHFVSLGFLRLFRAARLIRLLQQGYTIRILLWTFVQSFKALPYVCLLIGMLFFIYAIVGMQVFGNIWLNAATEINRHNNFQSFFNAVILLFRCATGEGWQDIMMAAVQGKDCARAGSAEINFEKGQTCGSNVSYAYFTSFVFLSSFLMLNLFVAVIMDNFDYLTRDSSILGPHHLDEFIRVWADYDPAATGRIHYSEMYEMLRIMAPPVGFGKKCPYRLAYKHLIRMNMPVAEDGTVHFTTTLFALIRESLSIKMRPVEEMDEADEELRLTLKKIWPLKAKKNMVDLVVPPNHELCFQKLTVGKIYAGLLILENYRARKSGTE 1680 HSP 2 Score: 706.057 bits (1821), Expect = 0.000e+0 Identity = 427/704 (60.65%), Postives = 517/704 (73.44%), Query Frame = 2 Query: 623 KTTSMRSLAKRTINLSFPGMQTSTSKSLFIFSEENVIRKYAKIIIEWGPFEYMVLLTILANCIVLSMERHLPKKDKTLLAGQLELTEKYFLGIFCVEALLKIVALGFCCHKEAYLRNVWNIMDFVVVVTGFLMMF----LNIDNHSDSSTVDLRTLRAVRVLRPLKLVAGFPSLQVVLKSIIRAMAPLLQIGLLVLFAITIFAIIGLEFYSGAFHYTCFKANSDKLPLPIPTEKSLVPCSNSKNGSGLGAYTCP-EDYQCKAYWEGPNYGITSFDNIGYAMLTVFQCITMEGWTDIMYHTNDAIGNRFNWLYFVPLIILGSFFMLNLVLGVLSGXXXXXXXXXXXXXXXLKLRRQQQTEKEFNGYMEWIQKAEEVLLNEATTTSEDKMRIIAARRRAEKQKYKLLGKNQSI--PDFEYEDTELYSETKSMKGNIFIRSYAGIRRRRKERCTSFWRTEKHFRFSVRRLVKSQPFYWAVIILVFFNTVCVAIEHYEQGKWLTLFLNYAEYVFLCLFMMEMMIKMYGLSIRVYFQSSFNIFDCVVIAGSLFEIIYGIFVQDSSFGLSVLRALRLLRIFKVTRYWAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXGMQLFGGEFNFEEGKPPQNFDTFVKALLTVFQILTGEDWNTVMYNGIQSKGGVKERGTVFSIYFVLLVVFGNYTLLNVFLAIAVDNLAN 2713 K S + K T++ + P + S SLFIF+E+N+IR+ AK IIEWGPFEY +LLTI+ NC+VLSME+HLPK DK L+ LE TE YF+GIFC+E +LK++A GF HK +YLR+ WNIMDF+VVV+G + M + +VDLRTLRAVRVLRPLKLV+G PSLQVVLKSI+ AMAPLLQIGLLVLFAI IFAIIGLEFYSGAFH C+ + + +E+ + PC+N S +G Y C + C W GPNYGITSFDNIG+AM+TVFQCITMEGWT +MY+TND++G+ +NW YF+PLI+LGSFFMLNLVLGVLSGEFAKERERVE RR FLKLRRQQQ E+E NGY+EWI AEEV+L E TT E+K I+ ARRRA +K K K QS + ED + E +G +A R+++ C S + K R +R +VK+Q FYW+VI LVF NT CVA EHY Q +W T FL YAE+VFL +F++EM++K++ + R YF S FN FDCVVI GS E+I+ V SFG+SV+RALRLLRIFK+T YW SLRNLV SL+NSMRSIISLLFLLFLFILIFALLGMQLFGG FNF P +FDTF AL+TVFQILTGEDWN VMY I+S+GG+ G +SIYF++LV+FGNYTLLNVFLAIAVDNLAN Sbjct: 154 KAESGTFVRKTTLSSNAPVKEKGPS-SLFIFAEDNIIRRNAKAIIEWGPFEYFILLTIIGNCVVLSMEQHLPKNDKKALSEWLERTEPYFMGIFCLECVLKVIAFGFALHKGSYLRSGWNIMDFIVVVSGVVTMLPFSPATQTANQPVDSVDLRTLRAVRVLRPLKLVSGIPSLQVVLKSILCAMAPLLQIGLLVLFAIIIFAIIGLEFYSGAFHSACYNERGE---IENVSERPM-PCTNKT--SPMGVYNCDVKGTTCLQKWIGPNYGITSFDNIGFAMITVFQCITMEGWTTVMYYTNDSLGSTYNWAYFIPLIVLGSFFMLNLVLGVLSGEFAKERERVENRREFLKLRRQQQIERELNGYLEWILTAEEVILKEDRTTEEEKAAIMEARRRAANKKLKQASKQQSTETEEDFEEDEDEMEEEYVDEGGTVEDEFA--ERKKRGCCHSVGKFIKQLRIQIRIMVKTQIFYWSVITLVFLNTCCVASEHYGQPQWFTDFLKYAEFVFLGIFVVEMLLKLFAMGSRTYFASKFNRFDCVVIVGSAAEVIWAE-VYGGSFGISVMRALRLLRIFKLTSYWVSLRNLVRSLMNSMRSIISLLFLLFLFILIFALLGMQLFGGRFNFPTMHPYTHFDTFPVALITVFQILTGEDWNEVMYLAIESQGGIYSGGWPYSIYFIVLVLFGNYTLLNVFLAIAVDNLAN 847 HSP 3 Score: 116.316 bits (290), Expect = 2.658e-25 Identity = 82/278 (29.50%), Postives = 137/278 (49.28%), Query Frame = 2 Query: 3089 SAMFIFSPLNSLRRFCHFVVNLRYFDLFIMIVICASSIALAAED--PVKEKSLKNNILEFFDYAFTGVFTVEMILKIIDLGIILHPGSYCRDLWNILDATVVICALVAFIMGQKPSPTGNKLRGSSAKNLNTIKSLRVLRVLRPLKTINRVPKLKAVFDCVVSSLKNVFNILIVYILFQFIFAVIAVQLFQGKFFYCNDASKSSRETCRGYFFDYAGRSTPETKK-----------------RLWQHHDF---HFDNILYAMLTLFTVTTGEGWPTVL 3856 S++FIF+ N +RR ++ F+ FI++ I + + L+ E P +K + LE + F G+F +E +LK+I G LH GSY R WNI+D VV+ +V + + T N+ S +++LR +RVLRPLK ++ +P L+ V ++ ++ + I ++ + IFA+I ++ + G F S+ RG + + R P T K + W ++ FDNI +AM+T+F T EGW TV+ Sbjct: 178 SSLFIFAEDNIIRRNAKAIIEWGPFEYFILLTIIGNCVVLSMEQHLPKNDKKALSEWLERTEPYFMGIFCLECVLKVIAFGFALHKGSYLRSGWNIMDFIVVVSGVVTMLPFSPATQTANQPVDSV-----DLRTLRAVRVLRPLKLVSGIPSLQVVLKSILCAMAPLLQIGLLVLFAIIIFAIIGLEFYSGAF-------HSACYNERGEIENVSERPMPCTNKTSPMGVYNCDVKGTTCLQKWIGPNYGITSFDNIGFAMITVFQCITMEGWTTVM 443 HSP 4 Score: 93.2041 bits (230), Expect = 2.711e-18 Identity = 73/274 (26.64%), Postives = 120/274 (43.80%), Query Frame = 2 Query: 701 SLFIFSEENVIRKYAKIIIEWGPFEYMVLLTILANCIVLSMERHLPKKDKTLLAGQLELTEKYFLGIFCVEALLKIVALGFCCHKEAYLRNVWNIMDFVVVVTG-FLMMFLNIDNHSDSSTVDLRTLRAVRVLRPLKLVAGFPSLQVVLKSIIRAMAPLLQIGLLVLFAITIFAIIGLEFYSGAFHYTCFKANSDKLPLPIPTEKSLVPCSNSKNGSGLGAYTCPEDYQCKAYWEGPNYGITSF--DNIGYAMLTVFQCITMEGWTDIMYHTND 1513 S+F S N R I+ FE MV+ I + + L+ E P ++ L+ + F G+F E LLK++ G H +Y R+ WNI+D +VV F F + + + +++LR +RVLRPLK + P L+ V ++ ++ + I ++ IFA+I ++ ++G F + C N K C G + ++ E + + F DN AMLT+F T EGW I ++ D Sbjct: 925 SMFFLSPTNPFRVLIHSIVCTKYFEMMVMTVICLSSVSLAAED--PVDEENPRNKVLQYMDYCFTGVFACEMLLKLIDQGILLHPGSYCRDFWNILDGIVVTCALFAFGFAGTEGSAGKNLNTIKSLRVLRVLRPLKTIKRIPKLKAVFDCVVNSLKNVFNILIVYFLFQFIFAVIAVQLFNGKFFF-CTDKN----------RKFANTCH--------GQFFVYDNQNDPPRVEQREWRLRPFNYDNTINAMLTLFVVTTGEGWPGIRQNSMD 1177 HSP 5 Score: 77.0258 bits (188), Expect = 2.150e-13 Identity = 71/320 (22.19%), Postives = 126/320 (39.38%), Query Frame = 2 Query: 698 KSLFIFSEENVIRKYAKIIIEWGPFEYMVLLTILANCIVLSMERHLPKKDKTLLAGQLELTEKYFLGIFCVEALLKIVALGFCCHKEAYLRNVWNIMDFVVVVTGFLMMFLNIDNHSDSSTVDLRTLRAVRVLRPLKLVAGFPSLQVVLKSIIRAMAPLLQIGLLVLFAITIFAIIGLEFYSGAFHYTCFKANSDKLPLPIPTEKSLVPCSNSKNGSGLGAYTCPEDYQCKAYWEGPNYGITSFDNIGYAMLTVFQCITMEGWTDIM------------------YHTNDAIGNRFNWLYFVPLIILGSFFMLNLVLGVL 1603 +SLF+ ++N + ++ PFEY ++ I N ++L M+ + + L L +F VE++LKI+A G Y R+ WN DFV VV + S LR RA R++R L+ G+ +++++L + +++ L + LL+ I+AI+G++ + + + N +F + A++ +F+C T EGW DIM + G+ ++ YF + L SF MLNL + V+ Sbjct: 1250 RSLFMPEDKNSTKYRIWRLVTSPPFEYFIMTMICCNTLILMMKYY---NNPLFYEEILRLFNTALTAVFTVESILKILAFGV----RNYFRDGWNRFDFVTVVGSITDALVTEFGGHFVSLGFLRLFRAARLIRLLQ--QGY-TIRILLWTFVQSFKALPYVCLLIGMLFFIYAIVGMQVFGNIWLNAATEINRHN----------------------------------------------NFQSFFNAVILLFRCATGEGWQDIMMAAVQGKDCARAGSAEINFEKGQTCGSNVSYAYFTSFVFLSSFLMLNLFVAVI 1513 HSP 6 Score: 75.0998 bits (183), Expect = 7.713e-13 Identity = 66/261 (25.29%), Postives = 128/261 (49.04%), Query Frame = 2 Query: 1982 RFSVRRLVKSQPFYWAVIILVFFNTVCVAIEHYEQGKWLTLFLNYAEYVFLCLFMMEMMIKMYGLSIRVYFQSSFNIFDCVVIAGSLFEIIY----GIFVQDSSFGLSVLRALRLLRIFKVTRYWAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXGMQLFGGEF--NFEEGKPPQNFDTFVKALLTVFQILTGEDWNTVMYNGIQSKGGVK--------ERG-----TVFSIYFVLLVVFGNYTLLNVFLAIAVDNL 2707 ++ + RLV S PF + ++ ++ NT+ + +++Y + L +F +E ++K+ +R YF+ +N FD V + GS+ + + G FV L LR R R+ ++ + ++R L+ + + S +++ + L+ + I+A++GMQ+FG + E NF +F A++ +F+ TGE W +M +Q K + E+G V YF V ++ +LN+F+A+ +DN Sbjct: 1262 KYRIWRLVTSPPFEYFIMTMICCNTLILMMKYYNNPLFYEEILRLFNTALTAVFTVESILKILAFGVRNYFRDGWNRFDFVTVVGSITDALVTEFGGHFV-----SLGFLRLFRAARLIRLLQQGYTIRILLWTFVQSFKALPYVCLLIGMLFFIYAIVGMQVFGNIWLNAATEINRHNNFQSFFNAVILLFRCATGEGWQDIMMAAVQGKDCARAGSAEINFEKGQTCGSNVSYAYFTSFVFLSSFLMLNLFVAVIMDNF 1517 HSP 7 Score: 67.781 bits (164), Expect = 1.355e-10 Identity = 65/283 (22.97%), Postives = 130/283 (45.94%), Query Frame = 2 Query: 4091 CRYMPKDKTTIKYRVWRLVVSTPFEYFIMVMIALNTLILMMKYYREEKKASSAATHDREQQAYLNYCNTLIFLNSAFTVMFSIECVLKIMAFGPKNYFRDPWNIFDFITVIGSITDVLVSELQDXXXXXXXXXXXXXXXXXXXXXXQGYTIRILLWTFIQSFKALPYVCLLIAMLFFIYSIIGMQVFG---NIKLISEYQINRHNNFQTFTNGLLLLFRCATGESWQEIMLACDNNKPCEKDIENTNNFDCGSNFTYIYFVSFIFLCSFLMLNLFVAVIMDNF 4930 C + K ++ ++ +V + F + ++ ++ LNT + ++Y + + + +L Y +FL +F +E +LK+ A G + YF +N FD + ++GS +V+ +E+ SF L ++R L+ + + S +++ + L+ + I++++GMQ+FG N + Y +F TF L+ +F+ TGE W E+M IE+ G IYF+ + ++ +LN+F+A+ +DN Sbjct: 594 CHSVGKFIKQLRIQIRIMVKTQIFYWSVITLVFLNTCCVASEHYGQPQWFTD----------FLKYAE-FVFLG-----IFVVEMLLKLFAMGSRTYFASKFNRFDCVVIVGSAAEVIWAEVYGGSFGISVMRALRLLRIFKLTSYW-VSLRNLVRSLMNSMRSIISLLFLLFLFILIFALLGMQLFGGRFNFPTMHPY-----THFDTFPVALITVFQILTGEDWNEVMYLA---------IESQGGIYSGGWPYSIYFIVLVLFGNYTLLNVFLAIAVDNL 845 HSP 8 Score: 55.8398 bits (133), Expect = 6.092e-7 Identity = 35/102 (34.31%), Postives = 51/102 (50.00%), Query Frame = 2 Query: 4157 PFEYFIMVMIALNTLILMMKYY--REEKKASSAATHDREQQAYLNYCNTLIFLNSAFTVMFSIECVLKIMAFG----PKNYFRDPWNIFDFITVIGSITDVL 4444 PFEYFI++ I N ++L M+ + + +KKA S E F +F +ECVLK++AFG +Y R WNI DFI V+ + +L Sbjct: 201 PFEYFILLTIIGNCVVLSMEQHLPKNDKKALSEWLERTE---------------PYFMGIFCLECVLKVIAFGFALHKGSYLRSGWNIMDFIVVVSGVVTML 287
BLAST of Voltage dependent L type calcium channel subunit vs. Ensembl Fly
Match: cac (gene:FBgn0263111 transcript:FBtr0332391) HSP 1 Score: 999.579 bits (2583), Expect = 0.000e+0 Identity = 564/978 (57.67%), Postives = 685/978 (70.04%), Query Frame = 2 Query: 3071 KPVLPYSAMFIFSPLNSLRRFCHFVVNLRYFDLFIMIVICASSIALAAEDPVKEKSLKNNILEFFDYAFTGVFTVEMILKIIDLGIILHPGSYCRDLWNILDATVVICALVAFIMGQKPSPTGNKLRGSSA-KNLNTIKSLRVLRVLRPLKTINRVPKLKAVFDCVVSSLKNVFNILIVYILFQFIFAVIAVQLFQGKFFYCNDASKSSRETCRGYFFDYA-GRSTPETKKRLWQHHDFHFDNILYAMLTLFTVTTGEGWPTVLKNSMESTNIDNGPIADYRQEMAXXXXXXXXXXXXXXXXXXXALIIITFQEQGENELIDLDLDKNQKQCIDFAINEKPLCRYMPKDKTTIKYRVWRLVVSTPFEYFIMVMIALNTLILMMKYYREEKKASSAATHDREQQAYLNYCNTLIFLNSAFTVMFSIECVLKIMAFGPKNYFRDPWNIFDFITVIGSITDVLVSEL-QDXXXXXXXXXXXXXXXXXXXXXXQGYTIRILLWTFIQSFKALPYVCLLIAMLFFIYSIIGMQVFGNIKLISEYQINRHNNFQTFTNGLLLLFRCATGESWQEIMLACDNNKPCEKDIENTNNFDCGSNFTYIYFVSFIFLCSFLMLNLFVAVIMDNFDYLTRDSSILGPHHLDEYIRVWAEYDPGAIGRIHHSEMYEMLRNMEPPVGFGKKCPYRLAYRKLIRMNMPVDENGTVNFTTTLFALIRESLNIKMSTAEYMDIKDMELRQTICKMWPVQAKKKLNLIVPPDSELVFHKMTVGKIYAGYLIVENWRAYKNSQ-EQG-PRSSPAVSIKSVTKPVVKEEKSANLLAKFFVAFKSNTNKSNISLDSHHERDEERFSIDHTYGEDYDANRRYSYLRRGSKP---------RGSKEIYSDLTPTQDYSYGLRPEHATIPGMPAPRKFGNRPRSPMYSLSELETKDRANTPQSLNSTIS---------PTSGDRESDKFHRRSPAVSPSNPQ 5935 KP+LPYS+MFI SP N +RR H+VVNL YFD FIM+VI SSIALAAEDPV+E S +N IL +FDYAFTGVFT+EM+LKI+DLG+ILHPGSY R+ WNI+DA VVICA V+F G + GSSA +NL+TIKSLRVLRVLRPLKTI RVPKLKAVFDCVV+SLKNV NILIVYILFQFIF+VI VQLF GKFFYC D SK + C+G +F Y P+ + R+W+ FH+DN+ AMLTLF V TGEGWP VL++SM +T D GPI ++R EM+IFYIV+FIVFPFFFVNIFVALIIITFQEQGE EL D ++DKNQK CIDF I +PL RYMPK++ T KY+VWR+VVSTPFEYFIM++I NTL+LMMKY+ + Y +L ++N FT MFS+E VLKI+ FG KN+F+DPWNIFD ITV+GSI D L E DS+ +++GFLRLFRAARLIKLLRQGYTIRILLWTF+QSFKALPYVCLLIAMLFFIY+IIGMQVFGNI+ + Q+NRHNNFQ+F+ G++LLFRCATGE+W IMLAC K C+ D E CGS Y YFVSFIF CSFLMLNLFVAVIMDNFDYLTRDSSILG HHLDE++R+WAEYDP A G+IH++EMY+ML+NM+PP+GFG KCP RLAY+KLIRMNMP+D+ V FTTTLFALIRE+L+IKM E MD DMELR+TI +WP+QAKK LNL+VPP +L K++VGKIYAG+LI+E+WR+ + Q + G PR + P EE L A + + +S D+ H H+Y + +RR LR P RG + I+ D+ + S + T PR + PR P S S + R+ +P +S PT G + +RS + SP+ Q Sbjct: 741 KPMLPYSSMFILSPTNPIRRGAHWVVNLPYFDFFIMVVISMSSIALAAEDPVRENSRRNKILNYFDYAFTGVFTIEMLLKIVDLGVILHPGSYLREFWNIMDAVVVICAAVSF---------GFDMSGSSAGQNLSTIKSLRVLRVLRPLKTIKRVPKLKAVFDCVVNSLKNVVNILIVYILFQFIFSVIGVQLFNGKFFYCTDESKHTSAECQGSYFKYEEDELLPKQELRVWKPRAFHYDNVAAAMLTLFAVQTGEGWPQVLQHSMAATYEDRGPIQNFRIEMSIFYIVYFIVFPFFFVNIFVALIIITFQEQGEAELQDGEIDKNQKSCIDFTIGARPLERYMPKNRNTFKYKVWRIVVSTPFEYFIMMLIVFNTLLLMMKYHNQGDM----------------YEKSLKYINMGFTGMFSVETVLKIIGFGVKNFFKDPWNIFDLITVLGSIVDALWMEFGHDSNSINVGFLRLFRAARLIKLLRQGYTIRILLWTFVQSFKALPYVCLLIAMLFFIYAIIGMQVFGNIRYDPDTQLNRHNNFQSFSGGIMLLFRCATGEAWPNIMLACLKGKACDDDAEKAPGEYCGSTLAYAYFVSFIFFCSFLMLNLFVAVIMDNFDYLTRDSSILGAHHLDEFVRIWAEYDPNATGKIHYTEMYDMLKNMDPPLGFGNKCPNRLAYKKLIRMNMPLDDELRVQFTTTLFALIRENLSIKMRAPEEMDQADMELRETITNIWPLQAKKMLNLLVPPSDQLNKGKLSVGKIYAGFLILESWRSTRFGQLDSGMPRKKLEHDDEHKYSPTAVEEPMLELQD----ASRHPSQESLTGADAGH------LHPGHSY---MNGHRRSPSLRHNGSPLARSPSPRRRGHQYIHHDIGFSDTVSNVVEMVKET----RHPRHGNSHPRYPRGSWSASTSPARSPSPSRYGGHLSRSKRTQLPYPTYG---TTSLCQRSRSPSPARLQ 1673 HSP 2 Score: 731.095 bits (1886), Expect = 0.000e+0 Identity = 431/675 (63.85%), Postives = 512/675 (75.85%), Query Frame = 2 Query: 701 SLFIFSEENVIRKYAKIIIEWGPFEYMVLLTILANCIVLSMERHLPKKDKTLLAGQLELTEKYFLGIFCVEALLKIVALGFCCHKEAYLRNVWNIMDFVVVVTGFLMMFLNIDNHSDSSTVDLRTLRAVRVLRPLKLVAGFPSLQVVLKSIIRAMAPLLQIGLLVLFAITIFAIIGLEFYSGAFHYTCFK-ANSDKLPLPIPTEKSLVPCSNSKN--GSGLGAYTCPEDYQ-CKAYWEGPNYGITSFDNIGYAMLTVFQCITMEGWTDIMYHTNDAIGNRFNWLYFVPLIILGSFFMLNLVLGVLSGXXXXXXXXXXXXXXXLKLRRQQQTEKEFNGYMEWIQKAEEVLLNEATTTSEDKMRIIAARRRAEKQKYKLLGKNQSIPDFEYEDTELYSETKSMKGNIFIRSYAGIRRRRKERCTSFWRTEKHFRFSVRRLVKSQPFYWAVIILVFFNTVCVAIEHYEQGKWLTLFLNYAEYVFLCLFMMEMMIKMYGLSIRVYFQSSFNIFDCVVIAGSLFEIIYGIFVQDSSFGLSVLRALRLLRIFKVTRYWAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXGMQLFGGEFNFEEGKPPQNFDTFVKALLTVFQILTGEDWNTVMYNGIQSKGGVKERGTVFSIYFVLLVVFGNYTLLNVFLAIAVDNLAN 2713 SLFI +E+N IRKY + IIEW PFEY VLLTI+ANC+VL++E HLP DKT+LA +LE TE YFL IFCVEA LKI+ALG HK +YLRN+WNIMDF VVVTGF+ + I VDLRTLRA+RVLRPLKLV+G PSLQVVLKSII+AMAPLLQIGLLVLFAI IFAIIGLEFYSGA H TC+ + +KL + +S PC N+ N G++ C C WEGPN GITSFDNIG+AMLTVFQCITMEGWT I+Y TNDA+G+ FNW+YFVPLI++GSFFMLNLVLGVLSGEF+ ER RVE+R F K R + + Y++WI +AEEV+L E TT E+KM I+ ARRR ++ KL +S + DTE + + ++++ R + + CT FWR EK FRF +R VK+Q FYW VI+LVF NTVCVA+EHY Q +LT FL YAE++FL LFM EM IKMY L R+YF+SSFN FDCVVI+GS+FE+I+ V+ SFGLSVLRALRLLRIFKVT+YW+SLRNLV+SLLNSMRSIISLLFLLFLFILIFALLGMQLFGG+FN G P NF+TF ALLTVFQILTGEDWN VMY GI S+GG ++G ++SIYF++LV+FGNYTLLNVFLAIAVDNLAN Sbjct: 17 SLFILTEDNPIRKYTRFIIEWPPFEYAVLLTIIANCVVLALEEHLPGGDKTVLAQKLEKTEAYFLCIFCVEASLKILALGLVLHKHSYLRNIWNIMDFFVVVTGFMTQYPQI-----GPEVDLRTLRAIRVLRPLKLVSGIPSLQVVLKSIIKAMAPLLQIGLLVLFAIVIFAIIGLEFYSGALHKTCYSLEDPNKL---VKEGESETPC-NTDNILEKATGSFVCNNTTSMCLEKWEGPNSGITSFDNIGFAMLTVFQCITMEGWTAILYWTNDALGSAFNWIYFVPLIVIGSFFMLNLVLGVLSGEFSNERNRVERRMEFQKCRFRAMFQTAMVSYLDWITQAEEVILAEERTTEEEKMHIMEARRRNAAKRKKLKSLGKS----KSTDTEEEEAEEDYGDDGYLKT----RSKPQGSCTGFWRAEKRFRFWIRHTVKTQWFYWFVIVLVFLNTVCVAVEHYGQPSFLTEFLYYAEFIFLGLFMSEMFIKMYALGPRIYFESSFNRFDCVVISGSIFEVIWSE-VKGGSFGLSVLRALRLLRIFKVTKYWSSLRNLVISLLNSMRSIISLLFLLFLFILIFALLGMQLFGGQFNLPGGTPETNFNTFPIALLTVFQILTGEDWNEVMYQGIISQGGA-QKGMIYSIYFIVLVLFGNYTLLNVFLAIAVDNLAN 672 HSP 3 Score: 117.472 bits (293), Expect = 1.246e-25 Identity = 79/275 (28.73%), Postives = 136/275 (49.45%), Query Frame = 2 Query: 701 SLFIFSEENVIRKYAKIIIEWGPFEYMVLLTILANCIVLSMERHLPKKDKTLLAGQLELTEKYFLGIFCVEALLKIVALGFCCHKEAYLRNVWNIMDFVVVVTGFLMMFLNIDNHSDSSTVD-LRTLRAVRVLRPLKLVAGFPSLQVVLKSIIRAMAPLLQIGLLVLFAITIFAIIGLEFYSGAFHYTCFKANSDKLPLPIPTEKSLVPCSNSKNGSGLGAYTCPEDYQCKAYWEGPNYGITSF--DNIGYAMLTVFQCITMEGWTDIMYHTNDA 1516 S+FI S N IR+ A ++ F++ +++ I + I L+ E P ++ + L + F G+F +E LLKIV LG H +YLR WNIMD VVV+ + ++ S + +++LR +RVLRPLK + P L+ V ++ ++ ++ I ++ + IF++IG++ ++G F Y +D+ S + G+Y E+ + E + +F DN+ AMLT+F T EGW ++ H+ A Sbjct: 748 SMFILSPTNPIRRGAHWVVNLPYFDFFIMVVISMSSIALAAED--PVRENSRRNKILNYFDYAFTGVFTIEMLLKIVDLGVILHPGSYLREFWNIMDAVVVICAAVSFGFDMSGSSAGQNLSTIKSLRVLRVLRPLKTIKRVPKLKAVFDCVVNSLKNVVNILIVYILFQFIFSVIGVQLFNGKFFYC-----TDE--------------SKHTSAECQGSYFKYEEDELLPKQELRVWKPRAFHYDNVAAAMLTLFAVQTGEGWPQVLQHSMAA 1001 HSP 4 Score: 113.235 bits (282), Expect = 2.294e-24 Identity = 78/288 (27.08%), Postives = 140/288 (48.61%), Query Frame = 2 Query: 3053 PETIQRKPVLPYSAMFIFSPLNSLRRFCHFVVNLRYFDLFIMIVICASSIALAAED--PVKEKSLKNNILEFFDYAFTGVFTVEMILKIIDLGIILHPGSYCRDLWNILDATVVICALVAFIMGQKPSPTGNKLRGSSAKNLNTIKSLRVLRVLRPLKTINRVPKLKAVFDCVVSSLKNVFNILIVYILFQFIFAVIAVQLFQGKF----FYCNDASKSSRE-----------TCRGYFFDYAGRSTPETKKRLWQHHD---FHFDNILYAMLTLFTVTTGEGWPTVL 3856 P+ + P +++FI + N +R++ F++ F+ +++ I A+ + LA E+ P +K++ LE + F +F VE LKI+ LG++LH SY R++WNI+D VV+ M Q P G ++ +++LR +RVLRPLK ++ +P L+ V ++ ++ + I ++ + IFA+I ++ + G + D +K +E + +T W+ + FDNI +AMLT+F T EGW +L Sbjct: 4 PKKEENPPGGGPTSLFILTEDNPIRKYTRFIIEWPPFEYAVLLTIIANCVVLALEEHLPGGDKTVLAQKLEKTEAYFLCIFCVEASLKILALGLVLHKHSYLRNIWNIMDFFVVVTGF----MTQYPQ-IGPEV---------DLRTLRAIRVLRPLKLVSGIPSLQVVLKSIIKAMAPLLQIGLLVLFAIVIFAIIGLEFYSGALHKTCYSLEDPNKLVKEGESETPCNTDNILEKATGSFVCNNTTSMCLEKWEGPNSGITSFDNIGFAMLTVFQCITMEGWTAIL 277 HSP 5 Score: 97.4413 bits (241), Expect = 1.695e-19 Identity = 72/258 (27.91%), Postives = 137/258 (53.10%), Query Frame = 2 Query: 1979 FRFSVRRLVKSQPFYWAVIILVFFNTVCVAIEHYEQGKWLTLFLNYAEYVFLCLFMMEMMIKMYGLSIRVYFQSSFNIFDCVVIAGSLFEIIYGIFVQDS-SFGLSVLRALRLLRIFKVTRYWAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXGMQLFGGEFNFEEGKPPQ-----NFDTFVKALLTVFQILTGEDWNTVMYNGIQSKG---------GVKERGTVFSIYFVLLVVFGNYTLLNVFLAIAVDNL 2707 F++ V R+V S PF + +++L+ FNT+ + ++++ QG L Y F +F +E ++K+ G ++ +F+ +NIFD + + GS+ + ++ F DS S + LR R R+ K+ R ++R L+ + + S +++ + L+ + I+A++GMQ+FG N Q NF +F ++ +F+ TGE W +M ++ K G T+ YFV + F ++ +LN+F+A+ +DN Sbjct: 1084 FKYKVWRIVVSTPFEYFIMMLIVFNTLLLMMKYHNQGDMYEKSLKYINMGFTGMFSVETVLKIIGFGVKNFFKDPWNIFDLITVLGSIVDALWMEFGHDSNSINVGFLRLFRAARLIKLLRQGYTIRILLWTFVQSFKALPYVCLLIAMLFFIYAIIGMQVFG---NIRYDPDTQLNRHNNFQSFSGGIMLLFRCATGEAWPNIMLACLKGKACDDDAEKAPGEYCGSTLAYAYFVSFIFFCSFLMLNLFVAVIMDNF 1338 HSP 6 Score: 78.5666 bits (192), Expect = 9.302e-14 Identity = 69/293 (23.55%), Postives = 126/293 (43.00%), Query Frame = 2 Query: 767 PFEYMVLLTILANCIVLSMERHLPKKDKTLLAGQLELTEKYFLGIFCVEALLKIVALGFCCHKEAYLRNVWNIMDFVVVVTGFLMMFLNIDNHSDSSTVDLRTLRAVRVLRPLKLVAGFPSLQVVLKSIIRAMAPLLQIGLLVLFAITIFAIIGLEFYSGAFHYTCFKANSDKLPLPIPTEKSLVPCSNSKNGSGLGAYTCPEDYQCKAYWEGPNYGITSFDNIGYAMLTVFQCITMEGWTDIMYHT-------NDA-------IGNRFNWLYFVPLIILGSFFMLNLVLGVL 1603 PFEY +++ I+ N ++L M+ H + L+ F G+F VE +LKI+ G + + ++ WNI D + V+ G ++ L ++ DS+++++ LR R R +KL+ +++++L + +++ L + LL+ I+AIIG++ + G Y D Q + +F + ++ +F+C T E W +IM +DA G+ + YFV I SF MLNL + V+ Sbjct: 1096 PFEYFIMMLIVFNTLLLMMKYH---NQGDMYEKSLKYINMGFTGMFSVETVLKIIGFGV----KNFFKDPWNIFDLITVL-GSIVDALWMEFGHDSNSINVGFLRLFRAARLIKLLRQGYTIRILLWTFVQSFKALPYVCLLIAMLFFIYAIIGMQVF-GNIRYD-------------------------------------PDTQLNRH--------NNFQSFSGGIMLLFRCATGEAWPNIMLACLKGKACDDDAEKAPGEYCGSTLAYAYFVSFIFFCSFLMLNLFVAVI 1334 HSP 7 Score: 72.7886 bits (177), Expect = 4.379e-12 Identity = 80/306 (26.14%), Postives = 137/306 (44.77%), Query Frame = 2 Query: 4043 KNQKQCIDFAINEKPLCRYMPKDKTTIKYRVW-RLVVSTP-FEYFIMVMIALNTLILMMKYYREEKKASSAATHDREQQAYLN---YCNTLIFLNSAFTVMFSIECVLKIMAFGPKNYFRDPWNIFDFITVIGSITDVLVSELQDXXXXXXXXXXXXXXXXXXXXXXQGYTIRILLWTFIQSFKALPYVCLLIAMLFFIYSIIGMQVFGNIKLISEYQIN-----RHNNFQTFTNGLLLLFRCATGESWQEIMLACDNNKPCEKDIENTNNFDCGSNFTYIYFVSFIFLCSFLMLNLFVAVIMDNF 4930 K Q C F EK ++R W R V T F +F++V++ LNT+ + +++Y Q ++L Y IFL +F E +K+ A GP+ YF +N FD + + GSI +V+ SE++ SF L ++R L+ + + S +++ + L+ + I++++GMQ+FG Q N NF TF LL +F+ TGE W E+M + I + G ++ IYF+ + ++ +LN+F+A+ +DN Sbjct: 415 KPQGSCTGFWRAEK-------------RFRFWIRHTVKTQWFYWFVIVLVFLNTVCVAVEHY--------------GQPSFLTEFLYYAEFIFLG-----LFMSEMFIKMYALGPRIYFESSFNRFDCVVISGSIFEVIWSEVKGGSFGLSVLRALRLLRIFKVTKYWS-SLRNLVISLLNSMRSIISLLFLLFLFILIFALLGMQLFGG-------QFNLPGGTPETNFNTFPIALLTVFQILTGEDWNEVMY---------QGIISQGGAQKGMIYS-IYFIVLVLFGNYTLLNVFLAIAVDNL 670
BLAST of Voltage dependent L type calcium channel subunit vs. Ensembl Fly
Match: cac (gene:FBgn0263111 transcript:FBtr0307313) HSP 1 Score: 993.801 bits (2568), Expect = 0.000e+0 Identity = 558/976 (57.17%), Postives = 677/976 (69.36%), Query Frame = 2 Query: 3071 KPVLPYSAMFIFSPLNSLRRFCHFVVNLRYFDLFIMIVICASSIALAAEDPVKEKSLKNNILEFFDYAFTGVFTVEMILKIIDLGIILHPGSYCRDLWNILDATVVICALVAFIMGQKPSPTGNKLRGSSA-KNLNTIKSLRVLRVLRPLKTINRVPKLKAVFDCVVSSLKNVFNILIVYILFQFIFAVIAVQLFQGKFFYCNDASKSSRETCRGYFFDYAGRST-PETKKRLWQHHDFHFDNILYAMLTLFTVTTGEGWPTVLKNSMESTNIDNGPIADYRQEMAXXXXXXXXXXXXXXXXXXXALIIITFQEQGENELIDLDLDKNQKQCIDFAINEKPLCRYMPKDKTTIKYRVWRLVVSTPFEYFIMVMIALNTLILMMKYYREEKKASSAATHDREQQAYLNYCNTLIFLNSAFTVMFSIECVLKIMAFGPKNYFRDPWNIFDFITVIGSITDVLVSELQDXXXXXXXXXXXXXXXXXXXXXXQGYTIRILLWTFIQSFKALPYVCLLIAMLFFIYSIIGMQVFGNIKLIS-EYQINRHNNFQTFTNGLLLLFRCATGESWQEIMLACDNNKPCEKDIENTNNFDCGSNFTYIYFVSFIFLCSFLMLNLFVAVIMDNFDYLTRDSSILGPHHLDEYIRVWAEYDPGAIGRIHHSEMYEMLRNMEPPVGFGKKCPYRLAYRKLIRMNMPVDENGTVNFTTTLFALIRESLNIKMSTAEYMDIKDMELRQTICKMWPVQAKKKLNLIVPPDSELVFHKMTVGKIYAGYLIVENWRAYKNSQEQGPRSSPAVSIKSVTKPVVKEEKSANLLAKFFVAFKSNTNKSNISLDSHHERDEERFSIDHTYGEDYDANRRYSYLRRGSKP---------RGSKEIYSDLTPTQDYSYGLRPEHATIPGMPAPRKFGNRPRSPMYSLSELETKDRANTPQSLNSTIS---------PTSGDRESDKFHRRSPAVSPSNPQ 5935 KP+LPYS+MFI SP N +RR H+VVNL YFD FIM+VI SSIALAAEDPV+E S +N IL +FDYAFTGVFT+EM+LKI+DLG+ILHPGSY R+ WNI+DA VVICA V+F G + GSSA +NL+TIKSLRVLRVLRPLKTI RVPKLKAVFDCVV+SLKNV NILIVYILFQFIF+VI VQLF GKFFYC D SK + C+G +F Y P+ + R+W+ FH+DN+ AMLTLF V TGEGWP VL++SM +T D GPI ++R EM+IFYIV+FIVFPFFFVNIFVALIIITFQEQGE EL D ++DKNQK CIDF I +PL RYMPK++ T KY+VWR+VVSTPFEYFIM++I NTL+LMMKY+ + Y +L ++N FT MFS+E VLKI+ FG KN+F+DPWNIFD ITV+GSI D L E DS+ +++GFLRLFRAARLIKLLRQGYTIRILLWTF+QSFKALPYVCLLIAMLFFIY+IIGMQVFGNIKL + E I RHNNFQ+F G++LLFRCATGE+W IMLAC K C+ D E CGS Y YFVSFIF CSFLMLNLFVAVIMDNFDYLTRDSSILG HHLDE++R+WAEYDP A G+IH++EMY+ML+NM+PP+GFG KCP RLAY+KLIRMNMP+D+ V FTTTLFALIRE+L+IKM E MD DMELR+TI +WP+QAKK LNL+VPP +L K++VGKIYAG+LI+E+WR+ + Q P + ++ ++ +E + D H+Y + +RR LR P RG + I+ D+ + S + T PR + PR P S S + R+ +P +S PT G + +RS + SP+ Q Sbjct: 741 KPMLPYSSMFILSPTNPIRRGAHWVVNLPYFDFFIMVVISMSSIALAAEDPVRENSRRNKILNYFDYAFTGVFTIEMLLKIVDLGVILHPGSYLREFWNIMDAVVVICAAVSF---------GFDMSGSSAGQNLSTIKSLRVLRVLRPLKTIKRVPKLKAVFDCVVNSLKNVVNILIVYILFQFIFSVIGVQLFNGKFFYCTDESKHTSAECQGSYFKYEEDELLPKQELRVWKPRAFHYDNVAAAMLTLFAVQTGEGWPQVLQHSMAATYEDRGPIQNFRIEMSIFYIVYFIVFPFFFVNIFVALIIITFQEQGEAELQDGEIDKNQKSCIDFTIGARPLERYMPKNRNTFKYKVWRIVVSTPFEYFIMMLIVFNTLLLMMKYHNQGDM----------------YEKSLKYINMGFTGMFSVETVLKIIGFGVKNFFKDPWNIFDLITVLGSIVDALWMEFGDSNSINVGFLRLFRAARLIKLLRQGYTIRILLWTFVQSFKALPYVCLLIAMLFFIYAIIGMQVFGNIKLGTVENSITRHNNFQSFIQGVMLLFRCATGEAWPNIMLACLKGKACDDDAEKAPGEYCGSTLAYAYFVSFIFFCSFLMLNLFVAVIMDNFDYLTRDSSILGAHHLDEFVRIWAEYDPNATGKIHYTEMYDMLKNMDPPLGFGNKCPNRLAYKKLIRMNMPLDDELRVQFTTTLFALIRENLSIKMRAPEEMDQADMELRETITNIWPLQAKKMLNLLVPPSDQLNKGKLSVGKIYAGFLILESWRSTRFGQLDS--GMPMLELQDASRHPSQESLTG--------------------------ADAGHLHPGHSY---MNGHRRSPSLRHNGSPLARSPSPRRRGHQYIHHDIGFSDTVSNVVEMVKET----RHPRHGNSHPRYPRGSWSASTSPARSPSPSRYGGHLSRSKRTQLPYPTYG---TTSLCQRSRSPSPARLQ 1653 HSP 2 Score: 747.273 bits (1928), Expect = 0.000e+0 Identity = 444/677 (65.58%), Postives = 522/677 (77.10%), Query Frame = 2 Query: 701 SLFIFSEENVIRKYAKIIIEWGPFEYMVLLTILANCIVLSMERHLPKKDKTLLAGQLELTEKYFLGIFCVEALLKIVALGFCCHKEAYLRNVWNIMDFVVVVTGFLMMFL--NIDNHSDSSTVDLRTLRAVRVLRPLKLVAGFPSLQVVLKSIIRAMAPLLQIGLLVLFAITIFAIIGLEFYSGAFHYTCFK-ANSDKLPLPIPTEKSLVPCSNSKN--GSGLGAYTCPEDYQ-CKAYWEGPNYGITSFDNIGYAMLTVFQCITMEGWTDIMYHTNDAIGNRFNWLYFVPLIILGSFFMLNLVLGVLSGXXXXXXXXXXXXXXXLKLRRQQQTEKEFNGYMEWIQKAEEVLLNEATTTSEDKMRIIAARRRAEKQKYKLLGKNQSIPDFEYEDTELYSETKSMKGNIFIRSYAGIRRRRKERCTSFWRTEKHFRFSVRRLVKSQPFYWAVIILVFFNTVCVAIEHYEQGKWLTLFLNYAEYVFLCLFMMEMMIKMYGLSIRVYFQSSFNIFDCVVIAGSLFEIIYGIFVQDSSFGLSVLRALRLLRIFKVTRYWAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXGMQLFGGEFNFEEGKPPQNFDTFVKALLTVFQILTGEDWNTVMYNGIQSKGGVKERGTVFSIYFVLLVVFGNYTLLNVFLAIAVDNLAN 2713 SLFI +E+N IRKY + IIEW PFEY VLLTI+ANC+VL++E HLP DKT+LA +LE TE YFL IFCVEA LKI+ALG HK +YLRN+WNIMDF VVVTG + +F NID VDLR LR+ RVLRPLKLV+ PSLQVVLKSII+AMAPLLQIGLLVLFAI IFAIIGLEFYSGA H TC+ + +KL + +S PC N+ N G++ C C WEGPN GITSFDNIG+AMLTVFQCITMEGWT I+Y TNDA+G+ FNW+YFVPLI++GSFFMLNLVLGVLSGEFAKERE+VE R+ FLKLRRQQQ E+E NGY+EWI KAEEV+L E TT E+KM I+ ARRR ++ KL +S + DTE + + ++++ R + + CT FWR EK FRF +R VK+Q FYW VI+LVF NTVCVA+EHY Q +LT FL YAE++FL LFM EM IKMY L R+YF+SSFN FDCVVI+GS+FE+I+ V+ SFGLSVLRALRLLRIFKVT+YW+SLRNLV+SLLNSMRSIISLLFLLFLFILIFALLGMQLFGG+FN G P NF+TF ALLTVFQILTGEDWN VMY GI S+GG ++G ++SIYF++LV+FGNYTLLNVFLAIAVDNLAN Sbjct: 17 SLFILTEDNPIRKYTRFIIEWPPFEYAVLLTIIANCVVLALEEHLPGGDKTVLAQKLEKTEAYFLCIFCVEASLKILALGLVLHKHSYLRNIWNIMDFFVVVTGAMTIFAEANID-------VDLRMLRSFRVLRPLKLVSRIPSLQVVLKSIIKAMAPLLQIGLLVLFAIVIFAIIGLEFYSGALHKTCYSLEDPNKL---VKEGESETPC-NTDNILEKATGSFVCNNTTSMCLEKWEGPNSGITSFDNIGFAMLTVFQCITMEGWTAILYWTNDALGSAFNWIYFVPLIVIGSFFMLNLVLGVLSGEFAKEREKVENRQEFLKLRRQQQLERELNGYVEWICKAEEVILAEERTTEEEKMHIMEARRRNAAKRKKLKSLGKS----KSTDTEEEEAEEDYGDDGYLKT----RSKPQGSCTGFWRAEKRFRFWIRHTVKTQWFYWFVIVLVFLNTVCVAVEHYGQPSFLTEFLYYAEFIFLGLFMSEMFIKMYALGPRIYFESSFNRFDCVVISGSIFEVIWSE-VKGGSFGLSVLRALRLLRIFKVTKYWSSLRNLVISLLNSMRSIISLLFLLFLFILIFALLGMQLFGGQFNLPGGTPETNFNTFPIALLTVFQILTGEDWNEVMYQGIISQGGA-QKGMIYSIYFIVLVLFGNYTLLNVFLAIAVDNLAN 672 HSP 3 Score: 117.472 bits (293), Expect = 1.432e-25 Identity = 79/275 (28.73%), Postives = 136/275 (49.45%), Query Frame = 2 Query: 701 SLFIFSEENVIRKYAKIIIEWGPFEYMVLLTILANCIVLSMERHLPKKDKTLLAGQLELTEKYFLGIFCVEALLKIVALGFCCHKEAYLRNVWNIMDFVVVVTGFLMMFLNIDNHSDSSTVD-LRTLRAVRVLRPLKLVAGFPSLQVVLKSIIRAMAPLLQIGLLVLFAITIFAIIGLEFYSGAFHYTCFKANSDKLPLPIPTEKSLVPCSNSKNGSGLGAYTCPEDYQCKAYWEGPNYGITSF--DNIGYAMLTVFQCITMEGWTDIMYHTNDA 1516 S+FI S N IR+ A ++ F++ +++ I + I L+ E P ++ + L + F G+F +E LLKIV LG H +YLR WNIMD VVV+ + ++ S + +++LR +RVLRPLK + P L+ V ++ ++ ++ I ++ + IF++IG++ ++G F Y +D+ S + G+Y E+ + E + +F DN+ AMLT+F T EGW ++ H+ A Sbjct: 748 SMFILSPTNPIRRGAHWVVNLPYFDFFIMVVISMSSIALAAED--PVRENSRRNKILNYFDYAFTGVFTIEMLLKIVDLGVILHPGSYLREFWNIMDAVVVICAAVSFGFDMSGSSAGQNLSTIKSLRVLRVLRPLKTIKRVPKLKAVFDCVVNSLKNVVNILIVYILFQFIFSVIGVQLFNGKFFYC-----TDE--------------SKHTSAECQGSYFKYEEDELLPKQELRVWKPRAFHYDNVAAAMLTLFAVQTGEGWPQVLQHSMAA 1001 HSP 4 Score: 112.079 bits (279), Expect = 5.347e-24 Identity = 78/288 (27.08%), Postives = 137/288 (47.57%), Query Frame = 2 Query: 3053 PETIQRKPVLPYSAMFIFSPLNSLRRFCHFVVNLRYFDLFIMIVICASSIALAAED--PVKEKSLKNNILEFFDYAFTGVFTVEMILKIIDLGIILHPGSYCRDLWNILDATVVICALVAFIMGQKPSPTGNKLRGSSAKNLNTIKSLRVLRVLRPLKTINRVPKLKAVFDCVVSSLKNVFNILIVYILFQFIFAVIAVQLFQGKF----FYCNDASKSSRE-----------TCRGYFFDYAGRSTPETKKRLWQHHD---FHFDNILYAMLTLFTVTTGEGWPTVL 3856 P+ + P +++FI + N +R++ F++ F+ +++ I A+ + LA E+ P +K++ LE + F +F VE LKI+ LG++LH SY R++WNI+D VV+ TG + A ++ LR RVLRPLK ++R+P L+ V ++ ++ + I ++ + IFA+I ++ + G + D +K +E + +T W+ + FDNI +AMLT+F T EGW +L Sbjct: 4 PKKEENPPGGGPTSLFILTEDNPIRKYTRFIIEWPPFEYAVLLTIIANCVVLALEEHLPGGDKTVLAQKLEKTEAYFLCIFCVEASLKILALGLVLHKHSYLRNIWNIMDFFVVV--------------TGAMTIFAEANIDVDLRMLRSFRVLRPLKLVSRIPSLQVVLKSIIKAMAPLLQIGLLVLFAIVIFAIIGLEFYSGALHKTCYSLEDPNKLVKEGESETPCNTDNILEKATGSFVCNNTTSMCLEKWEGPNSGITSFDNIGFAMLTVFQCITMEGWTAIL 277 HSP 5 Score: 98.9821 bits (245), Expect = 4.862e-20 Identity = 70/258 (27.13%), Postives = 139/258 (53.88%), Query Frame = 2 Query: 1979 FRFSVRRLVKSQPFYWAVIILVFFNTVCVAIEHYEQGKWLTLFLNYAEYVFLCLFMMEMMIKMYGLSIRVYFQSSFNIFDCVVIAGSLFEIIYGIFVQDSSFGLSVLRALRLLRIFKVTRYWAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXGMQLFGGEFNFEEGKPP------QNFDTFVKALLTVFQILTGEDWNTVMYNGIQSKG---------GVKERGTVFSIYFVLLVVFGNYTLLNVFLAIAVDNL 2707 F++ V R+V S PF + +++L+ FNT+ + ++++ QG L Y F +F +E ++K+ G ++ +F+ +NIFD + + GS+ + ++ F +S + LR R R+ K+ R ++R L+ + + S +++ + L+ + I+A++GMQ+FG N + G NF +F++ ++ +F+ TGE W +M ++ K G T+ YFV + F ++ +LN+F+A+ +DN Sbjct: 1084 FKYKVWRIVVSTPFEYFIMMLIVFNTLLLMMKYHNQGDMYEKSLKYINMGFTGMFSVETVLKIIGFGVKNFFKDPWNIFDLITVLGSIVDALWMEFGDSNSINVGFLRLFRAARLIKLLRQGYTIRILLWTFVQSFKALPYVCLLIAMLFFIYAIIGMQVFG---NIKLGTVENSITRHNNFQSFIQGVMLLFRCATGEAWPNIMLACLKGKACDDDAEKAPGEYCGSTLAYAYFVSFIFFCSFLMLNLFVAVIMDNF 1338 HSP 6 Score: 75.0998 bits (183), Expect = 9.221e-13 Identity = 71/297 (23.91%), Postives = 127/297 (42.76%), Query Frame = 2 Query: 767 PFEYMVLLTILANCIVLSMERHLPKKDKTLLAGQLELTEKYFLGIFCVEALLKIVALGFCCHKEAYLRNVWNIMDFVVV----VTGFLMMFLNIDNHSDSSTVDLRTLRAVRVLRPLKLVAGFPSLQVVLKSIIRAMAPLLQIGLLVLFAITIFAIIGLEFYSGAFHYTCFKANSDKLPLPIPTEKSLVPCSNSKNGSGLGAYTCPEDYQCKAYWEGPNYGITSFDNIGYAMLTVFQCITMEGWTDIMYHT-------NDA-------IGNRFNWLYFVPLIILGSFFMLNLVLGVL 1603 PFEY +++ I+ N ++L M+ H + L+ F G+F VE +LKI+ G + + ++ WNI D + V V M F DS+++++ LR R R +KL+ +++++L + +++ L + LL+ I+AIIG++ + N K G+ + T ++Q ++ +G ++ +F+C T E W +IM +DA G+ + YFV I SF MLNL + V+ Sbjct: 1096 PFEYFIMMLIVFNTLLLMMKYH---NQGDMYEKSLKYINMGFTGMFSVETVLKIIGFGV----KNFFKDPWNIFDLITVLGSIVDALWMEF------GDSNSINVGFLRLFRAARLIKLLRQGYTIRILLWTFVQSFKALPYVCLLIAMLFFIYAIIGMQVF-----------------------------GNIKLGTVENSITRHNNFQ--SFIQG--------------VMLLFRCATGEAWPNIMLACLKGKACDDDAEKAPGEYCGSTLAYAYFVSFIFFCSFLMLNLFVAVI 1334 HSP 7 Score: 72.4034 bits (176), Expect = 6.274e-12 Identity = 80/307 (26.06%), Postives = 137/307 (44.63%), Query Frame = 2 Query: 4040 DKNQKQCIDFAINEKPLCRYMPKDKTTIKYRVW-RLVVSTP-FEYFIMVMIALNTLILMMKYYREEKKASSAATHDREQQAYLN---YCNTLIFLNSAFTVMFSIECVLKIMAFGPKNYFRDPWNIFDFITVIGSITDVLVSELQDXXXXXXXXXXXXXXXXXXXXXXQGYTIRILLWTFIQSFKALPYVCLLIAMLFFIYSIIGMQVFGNIKLISEYQIN-----RHNNFQTFTNGLLLLFRCATGESWQEIMLACDNNKPCEKDIENTNNFDCGSNFTYIYFVSFIFLCSFLMLNLFVAVIMDNF 4930 K Q C F EK ++R W R V T F +F++V++ LNT+ + +++Y Q ++L Y IFL +F E +K+ A GP+ YF +N FD + + GSI +V+ SE++ SF L ++R L+ + + S +++ + L+ + I++++GMQ+FG Q N NF TF LL +F+ TGE W E+M + I + G ++ IYF+ + ++ +LN+F+A+ +DN Sbjct: 414 SKPQGSCTGFWRAEK-------------RFRFWIRHTVKTQWFYWFVIVLVFLNTVCVAVEHY--------------GQPSFLTEFLYYAEFIFLG-----LFMSEMFIKMYALGPRIYFESSFNRFDCVVISGSIFEVIWSEVKGGSFGLSVLRALRLLRIFKVTKYWS-SLRNLVISLLNSMRSIISLLFLLFLFILIFALLGMQLFGG-------QFNLPGGTPETNFNTFPIALLTVFQILTGEDWNEVMY---------QGIISQGGAQKGMIYS-IYFIVLVLFGNYTLLNVFLAIAVDNL 670
BLAST of Voltage dependent L type calcium channel subunit vs. Ensembl Fly
Match: cac (gene:FBgn0263111 transcript:FBtr0307314) HSP 1 Score: 993.416 bits (2567), Expect = 0.000e+0 Identity = 558/976 (57.17%), Postives = 677/976 (69.36%), Query Frame = 2 Query: 3071 KPVLPYSAMFIFSPLNSLRRFCHFVVNLRYFDLFIMIVICASSIALAAEDPVKEKSLKNNILEFFDYAFTGVFTVEMILKIIDLGIILHPGSYCRDLWNILDATVVICALVAFIMGQKPSPTGNKLRGSSA-KNLNTIKSLRVLRVLRPLKTINRVPKLKAVFDCVVSSLKNVFNILIVYILFQFIFAVIAVQLFQGKFFYCNDASKSSRETCRGYFFDYAGRST-PETKKRLWQHHDFHFDNILYAMLTLFTVTTGEGWPTVLKNSMESTNIDNGPIADYRQEMAXXXXXXXXXXXXXXXXXXXALIIITFQEQGENELIDLDLDKNQKQCIDFAINEKPLCRYMPKDKTTIKYRVWRLVVSTPFEYFIMVMIALNTLILMMKYYREEKKASSAATHDREQQAYLNYCNTLIFLNSAFTVMFSIECVLKIMAFGPKNYFRDPWNIFDFITVIGSITDVLVSELQDXXXXXXXXXXXXXXXXXXXXXXQGYTIRILLWTFIQSFKALPYVCLLIAMLFFIYSIIGMQVFGNIKLIS-EYQINRHNNFQTFTNGLLLLFRCATGESWQEIMLACDNNKPCEKDIENTNNFDCGSNFTYIYFVSFIFLCSFLMLNLFVAVIMDNFDYLTRDSSILGPHHLDEYIRVWAEYDPGAIGRIHHSEMYEMLRNMEPPVGFGKKCPYRLAYRKLIRMNMPVDENGTVNFTTTLFALIRESLNIKMSTAEYMDIKDMELRQTICKMWPVQAKKKLNLIVPPDSELVFHKMTVGKIYAGYLIVENWRAYKNSQEQGPRSSPAVSIKSVTKPVVKEEKSANLLAKFFVAFKSNTNKSNISLDSHHERDEERFSIDHTYGEDYDANRRYSYLRRGSKP---------RGSKEIYSDLTPTQDYSYGLRPEHATIPGMPAPRKFGNRPRSPMYSLSELETKDRANTPQSLNSTIS---------PTSGDRESDKFHRRSPAVSPSNPQ 5935 KP+LPYS+MFI SP N +RR H+VVNL YFD FIM+VI SSIALAAEDPV+E S +N IL +FDYAFTGVFT+EM+LKI+DLG+ILHPGSY R+ WNI+DA VVICA V+F G + GSSA +NL+TIKSLRVLRVLRPLKTI RVPKLKAVFDCVV+SLKNV NILIVYILFQFIF+VI VQLF GKFFYC D SK + C+G +F Y P+ + R+W+ FH+DN+ AMLTLF V TGEGWP VL++SM +T D GPI ++R EM+IFYIV+FIVFPFFFVNIFVALIIITFQEQGE EL D ++DKNQK CIDF I +PL RYMPK++ T KY+VWR+VVSTPFEYFIM++I NTL+LMMKY+ + Y +L ++N FT MFS+E VLKI+ FG KN+F+DPWNIFD ITV+GSI D L E DS+ +++GFLRLFRAARLIKLLRQGYTIRILLWTF+QSFKALPYVCLLIAMLFFIY+IIGMQVFGNIKL + E I RHNNFQ+F G++LLFRCATGE+W IMLAC K C+ D E CGS Y YFVSFIF CSFLMLNLFVAVIMDNFDYLTRDSSILG HHLDE++R+WAEYDP A G+IH++EMY+ML+NM+PP+GFG KCP RLAY+KLIRMNMP+D+ V FTTTLFALIRE+L+IKM E MD DMELR+TI +WP+QAKK LNL+VPP +L K++VGKIYAG+LI+E+WR+ + Q P + ++ ++ +E + D H+Y + +RR LR P RG + I+ D+ + S + T PR + PR P S S + R+ +P +S PT G + +RS + SP+ Q Sbjct: 741 KPMLPYSSMFILSPTNPIRRGAHWVVNLPYFDFFIMVVISMSSIALAAEDPVRENSRRNKILNYFDYAFTGVFTIEMLLKIVDLGVILHPGSYLREFWNIMDAVVVICAAVSF---------GFDMSGSSAGQNLSTIKSLRVLRVLRPLKTIKRVPKLKAVFDCVVNSLKNVVNILIVYILFQFIFSVIGVQLFNGKFFYCTDESKHTSAECQGSYFKYEEDELLPKQELRVWKPRAFHYDNVAAAMLTLFAVQTGEGWPQVLQHSMAATYEDRGPIQNFRIEMSIFYIVYFIVFPFFFVNIFVALIIITFQEQGEAELQDGEIDKNQKSCIDFTIGARPLERYMPKNRNTFKYKVWRIVVSTPFEYFIMMLIVFNTLLLMMKYHNQGDM----------------YEKSLKYINMGFTGMFSVETVLKIIGFGVKNFFKDPWNIFDLITVLGSIVDALWMEFGDSNSINVGFLRLFRAARLIKLLRQGYTIRILLWTFVQSFKALPYVCLLIAMLFFIYAIIGMQVFGNIKLGTVENSITRHNNFQSFIQGVMLLFRCATGEAWPNIMLACLKGKACDDDAEKAPGEYCGSTLAYAYFVSFIFFCSFLMLNLFVAVIMDNFDYLTRDSSILGAHHLDEFVRIWAEYDPNATGKIHYTEMYDMLKNMDPPLGFGNKCPNRLAYKKLIRMNMPLDDELRVQFTTTLFALIRENLSIKMRAPEEMDQADMELRETITNIWPLQAKKMLNLLVPPSDQLNKGKLSVGKIYAGFLILESWRSTRFGQLDS--GMPMLELQDASRHPSQESLTG--------------------------ADAGHLHPGHSY---MNGHRRSPSLRHNGSPLARSPSPRRRGHQYIHHDIGFSDTVSNVVEMVKET----RHPRHGNSHPRYPRGSWSASTSPARSPSPSRYGGHLSRSKRTQLPYPTYG---TTSLCQRSRSPSPARLQ 1653 HSP 2 Score: 729.554 bits (1882), Expect = 0.000e+0 Identity = 431/675 (63.85%), Postives = 512/675 (75.85%), Query Frame = 2 Query: 701 SLFIFSEENVIRKYAKIIIEWGPFEYMVLLTILANCIVLSMERHLPKKDKTLLAGQLELTEKYFLGIFCVEALLKIVALGFCCHKEAYLRNVWNIMDFVVVVTGFLMMFLNIDNHSDSSTVDLRTLRAVRVLRPLKLVAGFPSLQVVLKSIIRAMAPLLQIGLLVLFAITIFAIIGLEFYSGAFHYTCFK-ANSDKLPLPIPTEKSLVPCSNSKN--GSGLGAYTCPEDYQ-CKAYWEGPNYGITSFDNIGYAMLTVFQCITMEGWTDIMYHTNDAIGNRFNWLYFVPLIILGSFFMLNLVLGVLSGXXXXXXXXXXXXXXXLKLRRQQQTEKEFNGYMEWIQKAEEVLLNEATTTSEDKMRIIAARRRAEKQKYKLLGKNQSIPDFEYEDTELYSETKSMKGNIFIRSYAGIRRRRKERCTSFWRTEKHFRFSVRRLVKSQPFYWAVIILVFFNTVCVAIEHYEQGKWLTLFLNYAEYVFLCLFMMEMMIKMYGLSIRVYFQSSFNIFDCVVIAGSLFEIIYGIFVQDSSFGLSVLRALRLLRIFKVTRYWAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXGMQLFGGEFNFEEGKPPQNFDTFVKALLTVFQILTGEDWNTVMYNGIQSKGGVKERGTVFSIYFVLLVVFGNYTLLNVFLAIAVDNLAN 2713 SLFI +E+N IRKY + IIEW PFEY VLLTI+ANC+VL++E HLP DKT+LA +LE TE YFL IFCVEA LKI+ALG HK +YLRN+WNIMDF VVVTGF+ + I VDLRTLRA+RVLRPLKLV+G PSLQVVLKSII+AMAPLLQIGLLVLFAI IFAIIGLEFYSGA H TC+ + +KL + +S PC N+ N G++ C C WEGPN GITSFDNIG+AMLTVFQCITMEGWT I+Y TNDA+G+ FNW+YFVPLI++GSFFMLNLVLGVLSGEF+ ER RVE+R F K R + + Y++WI +AEEV+L E TT E+KM I+ ARRR ++ KL +S + DTE + + ++++ R + + CT FWR EK FRF +R VK+Q FYW VI+LVF NTVCVA+EHY Q +LT FL YAE++FL LFM EM IKMY L R+YF+SSFN FDCVVI+GS+FE+I+ V+ SFGLSVLRALRLLRIFKVT+YW+SLRNLV+SLLNSMRSIISLLFLLFLFILIFALLGMQLFGG+FN G P NF+TF ALLTVFQILTGEDWN VMY GI S+GG ++G ++SIYF++LV+FGNYTLLNVFLAIAVDNLAN Sbjct: 17 SLFILTEDNPIRKYTRFIIEWPPFEYAVLLTIIANCVVLALEEHLPGGDKTVLAQKLEKTEAYFLCIFCVEASLKILALGLVLHKHSYLRNIWNIMDFFVVVTGFMTQYPQI-----GPEVDLRTLRAIRVLRPLKLVSGIPSLQVVLKSIIKAMAPLLQIGLLVLFAIVIFAIIGLEFYSGALHKTCYSLEDPNKL---VKEGESETPC-NTDNILEKATGSFVCNNTTSMCLEKWEGPNSGITSFDNIGFAMLTVFQCITMEGWTAILYWTNDALGSAFNWIYFVPLIVIGSFFMLNLVLGVLSGEFSNERNRVERRMEFQKCRFRAMFQTAMVSYLDWITQAEEVILAEERTTEEEKMHIMEARRRNAAKRKKLKSLGKS----KSTDTEEEEAEEDYGDDGYLKT----RSKPQGSCTGFWRAEKRFRFWIRHTVKTQWFYWFVIVLVFLNTVCVAVEHYGQPSFLTEFLYYAEFIFLGLFMSEMFIKMYALGPRIYFESSFNRFDCVVISGSIFEVIWSE-VKGGSFGLSVLRALRLLRIFKVTKYWSSLRNLVISLLNSMRSIISLLFLLFLFILIFALLGMQLFGGQFNLPGGTPETNFNTFPIALLTVFQILTGEDWNEVMYQGIISQGGA-QKGMIYSIYFIVLVLFGNYTLLNVFLAIAVDNLAN 672 HSP 3 Score: 117.087 bits (292), Expect = 1.519e-25 Identity = 79/275 (28.73%), Postives = 136/275 (49.45%), Query Frame = 2 Query: 701 SLFIFSEENVIRKYAKIIIEWGPFEYMVLLTILANCIVLSMERHLPKKDKTLLAGQLELTEKYFLGIFCVEALLKIVALGFCCHKEAYLRNVWNIMDFVVVVTGFLMMFLNIDNHSDSSTVD-LRTLRAVRVLRPLKLVAGFPSLQVVLKSIIRAMAPLLQIGLLVLFAITIFAIIGLEFYSGAFHYTCFKANSDKLPLPIPTEKSLVPCSNSKNGSGLGAYTCPEDYQCKAYWEGPNYGITSF--DNIGYAMLTVFQCITMEGWTDIMYHTNDA 1516 S+FI S N IR+ A ++ F++ +++ I + I L+ E P ++ + L + F G+F +E LLKIV LG H +YLR WNIMD VVV+ + ++ S + +++LR +RVLRPLK + P L+ V ++ ++ ++ I ++ + IF++IG++ ++G F Y +D+ S + G+Y E+ + E + +F DN+ AMLT+F T EGW ++ H+ A Sbjct: 748 SMFILSPTNPIRRGAHWVVNLPYFDFFIMVVISMSSIALAAED--PVRENSRRNKILNYFDYAFTGVFTIEMLLKIVDLGVILHPGSYLREFWNIMDAVVVICAAVSFGFDMSGSSAGQNLSTIKSLRVLRVLRPLKTIKRVPKLKAVFDCVVNSLKNVVNILIVYILFQFIFSVIGVQLFNGKFFYC-----TDE--------------SKHTSAECQGSYFKYEEDELLPKQELRVWKPRAFHYDNVAAAMLTLFAVQTGEGWPQVLQHSMAA 1001 HSP 4 Score: 112.849 bits (281), Expect = 3.394e-24 Identity = 78/288 (27.08%), Postives = 140/288 (48.61%), Query Frame = 2 Query: 3053 PETIQRKPVLPYSAMFIFSPLNSLRRFCHFVVNLRYFDLFIMIVICASSIALAAED--PVKEKSLKNNILEFFDYAFTGVFTVEMILKIIDLGIILHPGSYCRDLWNILDATVVICALVAFIMGQKPSPTGNKLRGSSAKNLNTIKSLRVLRVLRPLKTINRVPKLKAVFDCVVSSLKNVFNILIVYILFQFIFAVIAVQLFQGKF----FYCNDASKSSRE-----------TCRGYFFDYAGRSTPETKKRLWQHHD---FHFDNILYAMLTLFTVTTGEGWPTVL 3856 P+ + P +++FI + N +R++ F++ F+ +++ I A+ + LA E+ P +K++ LE + F +F VE LKI+ LG++LH SY R++WNI+D VV+ M Q P G ++ +++LR +RVLRPLK ++ +P L+ V ++ ++ + I ++ + IFA+I ++ + G + D +K +E + +T W+ + FDNI +AMLT+F T EGW +L Sbjct: 4 PKKEENPPGGGPTSLFILTEDNPIRKYTRFIIEWPPFEYAVLLTIIANCVVLALEEHLPGGDKTVLAQKLEKTEAYFLCIFCVEASLKILALGLVLHKHSYLRNIWNIMDFFVVVTGF----MTQYPQ-IGPEV---------DLRTLRAIRVLRPLKLVSGIPSLQVVLKSIIKAMAPLLQIGLLVLFAIVIFAIIGLEFYSGALHKTCYSLEDPNKLVKEGESETPCNTDNILEKATGSFVCNNTTSMCLEKWEGPNSGITSFDNIGFAMLTVFQCITMEGWTAIL 277 HSP 5 Score: 98.9821 bits (245), Expect = 5.244e-20 Identity = 70/258 (27.13%), Postives = 139/258 (53.88%), Query Frame = 2 Query: 1979 FRFSVRRLVKSQPFYWAVIILVFFNTVCVAIEHYEQGKWLTLFLNYAEYVFLCLFMMEMMIKMYGLSIRVYFQSSFNIFDCVVIAGSLFEIIYGIFVQDSSFGLSVLRALRLLRIFKVTRYWAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXGMQLFGGEFNFEEGKPP------QNFDTFVKALLTVFQILTGEDWNTVMYNGIQSKG---------GVKERGTVFSIYFVLLVVFGNYTLLNVFLAIAVDNL 2707 F++ V R+V S PF + +++L+ FNT+ + ++++ QG L Y F +F +E ++K+ G ++ +F+ +NIFD + + GS+ + ++ F +S + LR R R+ K+ R ++R L+ + + S +++ + L+ + I+A++GMQ+FG N + G NF +F++ ++ +F+ TGE W +M ++ K G T+ YFV + F ++ +LN+F+A+ +DN Sbjct: 1084 FKYKVWRIVVSTPFEYFIMMLIVFNTLLLMMKYHNQGDMYEKSLKYINMGFTGMFSVETVLKIIGFGVKNFFKDPWNIFDLITVLGSIVDALWMEFGDSNSINVGFLRLFRAARLIKLLRQGYTIRILLWTFVQSFKALPYVCLLIAMLFFIYAIIGMQVFG---NIKLGTVENSITRHNNFQSFIQGVMLLFRCATGEAWPNIMLACLKGKACDDDAEKAPGEYCGSTLAYAYFVSFIFFCSFLMLNLFVAVIMDNF 1338 HSP 6 Score: 75.0998 bits (183), Expect = 9.946e-13 Identity = 71/297 (23.91%), Postives = 127/297 (42.76%), Query Frame = 2 Query: 767 PFEYMVLLTILANCIVLSMERHLPKKDKTLLAGQLELTEKYFLGIFCVEALLKIVALGFCCHKEAYLRNVWNIMDFVVV----VTGFLMMFLNIDNHSDSSTVDLRTLRAVRVLRPLKLVAGFPSLQVVLKSIIRAMAPLLQIGLLVLFAITIFAIIGLEFYSGAFHYTCFKANSDKLPLPIPTEKSLVPCSNSKNGSGLGAYTCPEDYQCKAYWEGPNYGITSFDNIGYAMLTVFQCITMEGWTDIMYHT-------NDA-------IGNRFNWLYFVPLIILGSFFMLNLVLGVL 1603 PFEY +++ I+ N ++L M+ H + L+ F G+F VE +LKI+ G + + ++ WNI D + V V M F DS+++++ LR R R +KL+ +++++L + +++ L + LL+ I+AIIG++ + N K G+ + T ++Q ++ +G ++ +F+C T E W +IM +DA G+ + YFV I SF MLNL + V+ Sbjct: 1096 PFEYFIMMLIVFNTLLLMMKYH---NQGDMYEKSLKYINMGFTGMFSVETVLKIIGFGV----KNFFKDPWNIFDLITVLGSIVDALWMEF------GDSNSINVGFLRLFRAARLIKLLRQGYTIRILLWTFVQSFKALPYVCLLIAMLFFIYAIIGMQVF-----------------------------GNIKLGTVENSITRHNNFQ--SFIQG--------------VMLLFRCATGEAWPNIMLACLKGKACDDDAEKAPGEYCGSTLAYAYFVSFIFFCSFLMLNLFVAVI 1334 HSP 7 Score: 72.4034 bits (176), Expect = 6.327e-12 Identity = 80/307 (26.06%), Postives = 137/307 (44.63%), Query Frame = 2 Query: 4040 DKNQKQCIDFAINEKPLCRYMPKDKTTIKYRVW-RLVVSTP-FEYFIMVMIALNTLILMMKYYREEKKASSAATHDREQQAYLN---YCNTLIFLNSAFTVMFSIECVLKIMAFGPKNYFRDPWNIFDFITVIGSITDVLVSELQDXXXXXXXXXXXXXXXXXXXXXXQGYTIRILLWTFIQSFKALPYVCLLIAMLFFIYSIIGMQVFGNIKLISEYQIN-----RHNNFQTFTNGLLLLFRCATGESWQEIMLACDNNKPCEKDIENTNNFDCGSNFTYIYFVSFIFLCSFLMLNLFVAVIMDNF 4930 K Q C F EK ++R W R V T F +F++V++ LNT+ + +++Y Q ++L Y IFL +F E +K+ A GP+ YF +N FD + + GSI +V+ SE++ SF L ++R L+ + + S +++ + L+ + I++++GMQ+FG Q N NF TF LL +F+ TGE W E+M + I + G ++ IYF+ + ++ +LN+F+A+ +DN Sbjct: 414 SKPQGSCTGFWRAEK-------------RFRFWIRHTVKTQWFYWFVIVLVFLNTVCVAVEHY--------------GQPSFLTEFLYYAEFIFLG-----LFMSEMFIKMYALGPRIYFESSFNRFDCVVISGSIFEVIWSEVKGGSFGLSVLRALRLLRIFKVTKYWS-SLRNLVISLLNSMRSIISLLFLLFLFILIFALLGMQLFGG-------QFNLPGGTPETNFNTFPIALLTVFQILTGEDWNEVMY---------QGIISQGGAQKGMIYS-IYFIVLVLFGNYTLLNVFLAIAVDNL 670
BLAST of Voltage dependent L type calcium channel subunit vs. Ensembl Fly
Match: cac (gene:FBgn0263111 transcript:FBtr0307316) HSP 1 Score: 989.949 bits (2558), Expect = 0.000e+0 Identity = 558/977 (57.11%), Postives = 677/977 (69.29%), Query Frame = 2 Query: 3071 KPVLPYSAMFIFSPLNSLRRFCHFVVNLRYFDLFIMIVICASSIALAAEDPVKEKSLKNNILEFFDYAFTGVFTVEMILKIIDLGIILHPGSYCRDLWNILDATVVICALVAFIMGQKPSPTGNKLRGSSA-KNLNTIKSLRVLRVLRPLKTINRVPKLKAVFDCVVSSLKNVFNILIVYILFQFIFAVIAVQLFQGKFFYCNDASKSSRETCRGYFFDYAGRST-PETKKRLWQHHDFHFDNILYAMLTLFTVTTGEGWPTVLKNSMESTNIDNGPIADYRQEMAXXXXXXXXXXXXXXXXXXXALIIITFQEQGENELIDLDLDKNQKQCIDFAINEKPLCRYMPKDKTTIKYRVWRLVVSTPFEYFIMVMIALNTLILMMKYYREEKKASSAATHDREQQAYLNYCNTLIFLNSAFTVMFSIECVLKIMAFGPKNYFRDPWNIFDFITVIGSITDVLVSEL-QDXXXXXXXXXXXXXXXXXXXXXXQGYTIRILLWTFIQSFKALPYVCLLIAMLFFIYSIIGMQVFGNIKLIS-EYQINRHNNFQTFTNGLLLLFRCATGESWQEIMLACDNNKPCEKDIENTNNFDCGSNFTYIYFVSFIFLCSFLMLNLFVAVIMDNFDYLTRDSSILGPHHLDEYIRVWAEYDPGAIGRIHHSEMYEMLRNMEPPVGFGKKCPYRLAYRKLIRMNMPVDENGTVNFTTTLFALIRESLNIKMSTAEYMDIKDMELRQTICKMWPVQAKKKLNLIVPPDSELVFHKMTVGKIYAGYLIVENWRAYKNSQEQGPRSSPAVSIKSVTKPVVKEEKSANLLAKFFVAFKSNTNKSNISLDSHHERDEERFSIDHTYGEDYDANRRYSYLRRGSKP---------RGSKEIYSDLTPTQDYSYGLRPEHATIPGMPAPRKFGNRPRSPMYSLSELETKDRANTPQSLNSTIS---------PTSGDRESDKFHRRSPAVSPSNPQ 5935 KP+LPYS+MFI SP N +RR H+VVNL YFD FIM+VI SSIALAAEDPV+E S +N IL +FDYAFTGVFT+EM+LKI+DLG+ILHPGSY R+ WNI+DA VVICA V+F G + GSSA +NL+TIKSLRVLRVLRPLKTI RVPKLKAVFDCVV+SLKNV NILIVYILFQFIF+VI VQLF GKFFYC D SK + C+G +F Y P+ + R+W+ FH+DN+ AMLTLF V TGEGWP VL++SM +T D GPI ++R EM+IFYIV+FIVFPFFFVNIFVALIIITFQEQGE EL D ++DKNQK CIDF I +PL RYMPK++ T KY+VWR+VVSTPFEYFIM++I NTL+LMMKY+ + Y +L ++N FT MFS+E VLKI+ FG KN+F+DPWNIFD ITV+GSI D L E DS+ +++GFLRLFRAARLIKLLRQGYTIRILLWTF+QSFKALPYVCLLIAMLFFIY+IIGMQVFGNIKL + E I RHNNFQ+F G++LLFRCATGE+W IMLAC K C+ D E CGS Y YFVSFIF CSFLMLNLFVAVIMDNFDYLTRDSSILG HHLDE++R+WAEYDP A G+IH++EMY+ML+NM+PP+GFG KCP RLAY+KLIRMNMP+D+ V FTTTLFALIRE+L+IKM E MD DMELR+TI +WP+QAKK LNL+VPP +L K++VGKIYAG+LI+E+WR+ + Q P + ++ ++ +E + D H+Y + +RR LR P RG + I+ D+ + S + T PR + PR P S S + R+ +P +S PT G + +RS + SP+ Q Sbjct: 741 KPMLPYSSMFILSPTNPIRRGAHWVVNLPYFDFFIMVVISMSSIALAAEDPVRENSRRNKILNYFDYAFTGVFTIEMLLKIVDLGVILHPGSYLREFWNIMDAVVVICAAVSF---------GFDMSGSSAGQNLSTIKSLRVLRVLRPLKTIKRVPKLKAVFDCVVNSLKNVVNILIVYILFQFIFSVIGVQLFNGKFFYCTDESKHTSAECQGSYFKYEEDELLPKQELRVWKPRAFHYDNVAAAMLTLFAVQTGEGWPQVLQHSMAATYEDRGPIQNFRIEMSIFYIVYFIVFPFFFVNIFVALIIITFQEQGEAELQDGEIDKNQKSCIDFTIGARPLERYMPKNRNTFKYKVWRIVVSTPFEYFIMMLIVFNTLLLMMKYHNQGDM----------------YEKSLKYINMGFTGMFSVETVLKIIGFGVKNFFKDPWNIFDLITVLGSIVDALWMEFGHDSNSINVGFLRLFRAARLIKLLRQGYTIRILLWTFVQSFKALPYVCLLIAMLFFIYAIIGMQVFGNIKLGTVENSITRHNNFQSFIQGVMLLFRCATGEAWPNIMLACLKGKACDDDAEKAPGEYCGSTLAYAYFVSFIFFCSFLMLNLFVAVIMDNFDYLTRDSSILGAHHLDEFVRIWAEYDPNATGKIHYTEMYDMLKNMDPPLGFGNKCPNRLAYKKLIRMNMPLDDELRVQFTTTLFALIRENLSIKMRAPEEMDQADMELRETITNIWPLQAKKMLNLLVPPSDQLNKGKLSVGKIYAGFLILESWRSTRFGQLDS--GMPMLELQDASRHPSQESLTG--------------------------ADAGHLHPGHSY---MNGHRRSPSLRHNGSPLARSPSPRRRGHQYIHHDIGFSDTVSNVVEMVKET----RHPRHGNSHPRYPRGSWSASTSPARSPSPSRYGGHLSRSKRTQLPYPTYG---TTSLCQRSRSPSPARLQ 1654 HSP 2 Score: 747.273 bits (1928), Expect = 0.000e+0 Identity = 444/677 (65.58%), Postives = 522/677 (77.10%), Query Frame = 2 Query: 701 SLFIFSEENVIRKYAKIIIEWGPFEYMVLLTILANCIVLSMERHLPKKDKTLLAGQLELTEKYFLGIFCVEALLKIVALGFCCHKEAYLRNVWNIMDFVVVVTGFLMMFL--NIDNHSDSSTVDLRTLRAVRVLRPLKLVAGFPSLQVVLKSIIRAMAPLLQIGLLVLFAITIFAIIGLEFYSGAFHYTCFK-ANSDKLPLPIPTEKSLVPCSNSKN--GSGLGAYTCPEDYQ-CKAYWEGPNYGITSFDNIGYAMLTVFQCITMEGWTDIMYHTNDAIGNRFNWLYFVPLIILGSFFMLNLVLGVLSGXXXXXXXXXXXXXXXLKLRRQQQTEKEFNGYMEWIQKAEEVLLNEATTTSEDKMRIIAARRRAEKQKYKLLGKNQSIPDFEYEDTELYSETKSMKGNIFIRSYAGIRRRRKERCTSFWRTEKHFRFSVRRLVKSQPFYWAVIILVFFNTVCVAIEHYEQGKWLTLFLNYAEYVFLCLFMMEMMIKMYGLSIRVYFQSSFNIFDCVVIAGSLFEIIYGIFVQDSSFGLSVLRALRLLRIFKVTRYWAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXGMQLFGGEFNFEEGKPPQNFDTFVKALLTVFQILTGEDWNTVMYNGIQSKGGVKERGTVFSIYFVLLVVFGNYTLLNVFLAIAVDNLAN 2713 SLFI +E+N IRKY + IIEW PFEY VLLTI+ANC+VL++E HLP DKT+LA +LE TE YFL IFCVEA LKI+ALG HK +YLRN+WNIMDF VVVTG + +F NID VDLR LR+ RVLRPLKLV+ PSLQVVLKSII+AMAPLLQIGLLVLFAI IFAIIGLEFYSGA H TC+ + +KL + +S PC N+ N G++ C C WEGPN GITSFDNIG+AMLTVFQCITMEGWT I+Y TNDA+G+ FNW+YFVPLI++GSFFMLNLVLGVLSGEFAKERE+VE R+ FLKLRRQQQ E+E NGY+EWI KAEEV+L E TT E+KM I+ ARRR ++ KL +S + DTE + + ++++ R + + CT FWR EK FRF +R VK+Q FYW VI+LVF NTVCVA+EHY Q +LT FL YAE++FL LFM EM IKMY L R+YF+SSFN FDCVVI+GS+FE+I+ V+ SFGLSVLRALRLLRIFKVT+YW+SLRNLV+SLLNSMRSIISLLFLLFLFILIFALLGMQLFGG+FN G P NF+TF ALLTVFQILTGEDWN VMY GI S+GG ++G ++SIYF++LV+FGNYTLLNVFLAIAVDNLAN Sbjct: 17 SLFILTEDNPIRKYTRFIIEWPPFEYAVLLTIIANCVVLALEEHLPGGDKTVLAQKLEKTEAYFLCIFCVEASLKILALGLVLHKHSYLRNIWNIMDFFVVVTGAMTIFAEANID-------VDLRMLRSFRVLRPLKLVSRIPSLQVVLKSIIKAMAPLLQIGLLVLFAIVIFAIIGLEFYSGALHKTCYSLEDPNKL---VKEGESETPC-NTDNILEKATGSFVCNNTTSMCLEKWEGPNSGITSFDNIGFAMLTVFQCITMEGWTAILYWTNDALGSAFNWIYFVPLIVIGSFFMLNLVLGVLSGEFAKEREKVENRQEFLKLRRQQQLERELNGYVEWICKAEEVILAEERTTEEEKMHIMEARRRNAAKRKKLKSLGKS----KSTDTEEEEAEEDYGDDGYLKT----RSKPQGSCTGFWRAEKRFRFWIRHTVKTQWFYWFVIVLVFLNTVCVAVEHYGQPSFLTEFLYYAEFIFLGLFMSEMFIKMYALGPRIYFESSFNRFDCVVISGSIFEVIWSE-VKGGSFGLSVLRALRLLRIFKVTKYWSSLRNLVISLLNSMRSIISLLFLLFLFILIFALLGMQLFGGQFNLPGGTPETNFNTFPIALLTVFQILTGEDWNEVMYQGIISQGGA-QKGMIYSIYFIVLVLFGNYTLLNVFLAIAVDNLAN 672 HSP 3 Score: 117.472 bits (293), Expect = 1.420e-25 Identity = 79/275 (28.73%), Postives = 136/275 (49.45%), Query Frame = 2 Query: 701 SLFIFSEENVIRKYAKIIIEWGPFEYMVLLTILANCIVLSMERHLPKKDKTLLAGQLELTEKYFLGIFCVEALLKIVALGFCCHKEAYLRNVWNIMDFVVVVTGFLMMFLNIDNHSDSSTVD-LRTLRAVRVLRPLKLVAGFPSLQVVLKSIIRAMAPLLQIGLLVLFAITIFAIIGLEFYSGAFHYTCFKANSDKLPLPIPTEKSLVPCSNSKNGSGLGAYTCPEDYQCKAYWEGPNYGITSF--DNIGYAMLTVFQCITMEGWTDIMYHTNDA 1516 S+FI S N IR+ A ++ F++ +++ I + I L+ E P ++ + L + F G+F +E LLKIV LG H +YLR WNIMD VVV+ + ++ S + +++LR +RVLRPLK + P L+ V ++ ++ ++ I ++ + IF++IG++ ++G F Y +D+ S + G+Y E+ + E + +F DN+ AMLT+F T EGW ++ H+ A Sbjct: 748 SMFILSPTNPIRRGAHWVVNLPYFDFFIMVVISMSSIALAAED--PVRENSRRNKILNYFDYAFTGVFTIEMLLKIVDLGVILHPGSYLREFWNIMDAVVVICAAVSFGFDMSGSSAGQNLSTIKSLRVLRVLRPLKTIKRVPKLKAVFDCVVNSLKNVVNILIVYILFQFIFSVIGVQLFNGKFFYC-----TDE--------------SKHTSAECQGSYFKYEEDELLPKQELRVWKPRAFHYDNVAAAMLTLFAVQTGEGWPQVLQHSMAA 1001 HSP 4 Score: 112.079 bits (279), Expect = 5.531e-24 Identity = 78/288 (27.08%), Postives = 137/288 (47.57%), Query Frame = 2 Query: 3053 PETIQRKPVLPYSAMFIFSPLNSLRRFCHFVVNLRYFDLFIMIVICASSIALAAED--PVKEKSLKNNILEFFDYAFTGVFTVEMILKIIDLGIILHPGSYCRDLWNILDATVVICALVAFIMGQKPSPTGNKLRGSSAKNLNTIKSLRVLRVLRPLKTINRVPKLKAVFDCVVSSLKNVFNILIVYILFQFIFAVIAVQLFQGKF----FYCNDASKSSRE-----------TCRGYFFDYAGRSTPETKKRLWQHHD---FHFDNILYAMLTLFTVTTGEGWPTVL 3856 P+ + P +++FI + N +R++ F++ F+ +++ I A+ + LA E+ P +K++ LE + F +F VE LKI+ LG++LH SY R++WNI+D VV+ TG + A ++ LR RVLRPLK ++R+P L+ V ++ ++ + I ++ + IFA+I ++ + G + D +K +E + +T W+ + FDNI +AMLT+F T EGW +L Sbjct: 4 PKKEENPPGGGPTSLFILTEDNPIRKYTRFIIEWPPFEYAVLLTIIANCVVLALEEHLPGGDKTVLAQKLEKTEAYFLCIFCVEASLKILALGLVLHKHSYLRNIWNIMDFFVVV--------------TGAMTIFAEANIDVDLRMLRSFRVLRPLKLVSRIPSLQVVLKSIIKAMAPLLQIGLLVLFAIVIFAIIGLEFYSGALHKTCYSLEDPNKLVKEGESETPCNTDNILEKATGSFVCNNTTSMCLEKWEGPNSGITSFDNIGFAMLTVFQCITMEGWTAIL 277 HSP 5 Score: 98.9821 bits (245), Expect = 5.803e-20 Identity = 72/259 (27.80%), Postives = 140/259 (54.05%), Query Frame = 2 Query: 1979 FRFSVRRLVKSQPFYWAVIILVFFNTVCVAIEHYEQGKWLTLFLNYAEYVFLCLFMMEMMIKMYGLSIRVYFQSSFNIFDCVVIAGSLFEIIYGIFVQDS-SFGLSVLRALRLLRIFKVTRYWAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXGMQLFGGEFNFEEGKPP------QNFDTFVKALLTVFQILTGEDWNTVMYNGIQSKG---------GVKERGTVFSIYFVLLVVFGNYTLLNVFLAIAVDNL 2707 F++ V R+V S PF + +++L+ FNT+ + ++++ QG L Y F +F +E ++K+ G ++ +F+ +NIFD + + GS+ + ++ F DS S + LR R R+ K+ R ++R L+ + + S +++ + L+ + I+A++GMQ+FG N + G NF +F++ ++ +F+ TGE W +M ++ K G T+ YFV + F ++ +LN+F+A+ +DN Sbjct: 1084 FKYKVWRIVVSTPFEYFIMMLIVFNTLLLMMKYHNQGDMYEKSLKYINMGFTGMFSVETVLKIIGFGVKNFFKDPWNIFDLITVLGSIVDALWMEFGHDSNSINVGFLRLFRAARLIKLLRQGYTIRILLWTFVQSFKALPYVCLLIAMLFFIYAIIGMQVFG---NIKLGTVENSITRHNNFQSFIQGVMLLFRCATGEAWPNIMLACLKGKACDDDAEKAPGEYCGSTLAYAYFVSFIFFCSFLMLNLFVAVIMDNF 1339 HSP 6 Score: 78.1814 bits (191), Expect = 1.195e-13 Identity = 70/293 (23.89%), Postives = 131/293 (44.71%), Query Frame = 2 Query: 767 PFEYMVLLTILANCIVLSMERHLPKKDKTLLAGQLELTEKYFLGIFCVEALLKIVALGFCCHKEAYLRNVWNIMDFVVVVTGFLMMFLNIDNHSDSSTVDLRTLRAVRVLRPLKLVAGFPSLQVVLKSIIRAMAPLLQIGLLVLFAITIFAIIGLEFYSGAFHYTCFKANSDKLPLPIPTEKSLVPCSNSKNGSGLGAYTCPEDYQCKAYWEGPNYGITSFDNIGYAMLTVFQCITMEGWTDIMYHT-------NDA-------IGNRFNWLYFVPLIILGSFFMLNLVLGVL 1603 PFEY +++ I+ N ++L M+ H + L+ F G+F VE +LKI+ G + + ++ WNI D + V+ G ++ L ++ DS+++++ LR R R +KL+ +++++L + +++ L + LL+ I+AIIG++ + N K G+ + T ++Q ++ +G ++ +F+C T E W +IM +DA G+ + YFV I SF MLNL + V+ Sbjct: 1096 PFEYFIMMLIVFNTLLLMMKYH---NQGDMYEKSLKYINMGFTGMFSVETVLKIIGFGV----KNFFKDPWNIFDLITVL-GSIVDALWMEFGHDSNSINVGFLRLFRAARLIKLLRQGYTIRILLWTFVQSFKALPYVCLLIAMLFFIYAIIGMQVF-----------------------------GNIKLGTVENSITRHNNFQ--SFIQG--------------VMLLFRCATGEAWPNIMLACLKGKACDDDAEKAPGEYCGSTLAYAYFVSFIFFCSFLMLNLFVAVI 1335 HSP 7 Score: 72.4034 bits (176), Expect = 6.435e-12 Identity = 80/307 (26.06%), Postives = 137/307 (44.63%), Query Frame = 2 Query: 4040 DKNQKQCIDFAINEKPLCRYMPKDKTTIKYRVW-RLVVSTP-FEYFIMVMIALNTLILMMKYYREEKKASSAATHDREQQAYLN---YCNTLIFLNSAFTVMFSIECVLKIMAFGPKNYFRDPWNIFDFITVIGSITDVLVSELQDXXXXXXXXXXXXXXXXXXXXXXQGYTIRILLWTFIQSFKALPYVCLLIAMLFFIYSIIGMQVFGNIKLISEYQIN-----RHNNFQTFTNGLLLLFRCATGESWQEIMLACDNNKPCEKDIENTNNFDCGSNFTYIYFVSFIFLCSFLMLNLFVAVIMDNF 4930 K Q C F EK ++R W R V T F +F++V++ LNT+ + +++Y Q ++L Y IFL +F E +K+ A GP+ YF +N FD + + GSI +V+ SE++ SF L ++R L+ + + S +++ + L+ + I++++GMQ+FG Q N NF TF LL +F+ TGE W E+M + I + G ++ IYF+ + ++ +LN+F+A+ +DN Sbjct: 414 SKPQGSCTGFWRAEK-------------RFRFWIRHTVKTQWFYWFVIVLVFLNTVCVAVEHY--------------GQPSFLTEFLYYAEFIFLG-----LFMSEMFIKMYALGPRIYFESSFNRFDCVVISGSIFEVIWSEVKGGSFGLSVLRALRLLRIFKVTKYWS-SLRNLVISLLNSMRSIISLLFLLFLFILIFALLGMQLFGG-------QFNLPGGTPETNFNTFPIALLTVFQILTGEDWNEVMY---------QGIISQGGAQKGMIYS-IYFIVLVLFGNYTLLNVFLAIAVDNL 670
BLAST of Voltage dependent L type calcium channel subunit vs. Ensembl Fly
Match: cac (gene:FBgn0263111 transcript:FBtr0307315) HSP 1 Score: 989.564 bits (2557), Expect = 0.000e+0 Identity = 558/977 (57.11%), Postives = 677/977 (69.29%), Query Frame = 2 Query: 3071 KPVLPYSAMFIFSPLNSLRRFCHFVVNLRYFDLFIMIVICASSIALAAEDPVKEKSLKNNILEFFDYAFTGVFTVEMILKIIDLGIILHPGSYCRDLWNILDATVVICALVAFIMGQKPSPTGNKLRGSSA-KNLNTIKSLRVLRVLRPLKTINRVPKLKAVFDCVVSSLKNVFNILIVYILFQFIFAVIAVQLFQGKFFYCNDASKSSRETCRGYFFDYAGRST-PETKKRLWQHHDFHFDNILYAMLTLFTVTTGEGWPTVLKNSMESTNIDNGPIADYRQEMAXXXXXXXXXXXXXXXXXXXALIIITFQEQGENELIDLDLDKNQKQCIDFAINEKPLCRYMPKDKTTIKYRVWRLVVSTPFEYFIMVMIALNTLILMMKYYREEKKASSAATHDREQQAYLNYCNTLIFLNSAFTVMFSIECVLKIMAFGPKNYFRDPWNIFDFITVIGSITDVLVSEL-QDXXXXXXXXXXXXXXXXXXXXXXQGYTIRILLWTFIQSFKALPYVCLLIAMLFFIYSIIGMQVFGNIKLIS-EYQINRHNNFQTFTNGLLLLFRCATGESWQEIMLACDNNKPCEKDIENTNNFDCGSNFTYIYFVSFIFLCSFLMLNLFVAVIMDNFDYLTRDSSILGPHHLDEYIRVWAEYDPGAIGRIHHSEMYEMLRNMEPPVGFGKKCPYRLAYRKLIRMNMPVDENGTVNFTTTLFALIRESLNIKMSTAEYMDIKDMELRQTICKMWPVQAKKKLNLIVPPDSELVFHKMTVGKIYAGYLIVENWRAYKNSQEQGPRSSPAVSIKSVTKPVVKEEKSANLLAKFFVAFKSNTNKSNISLDSHHERDEERFSIDHTYGEDYDANRRYSYLRRGSKP---------RGSKEIYSDLTPTQDYSYGLRPEHATIPGMPAPRKFGNRPRSPMYSLSELETKDRANTPQSLNSTIS---------PTSGDRESDKFHRRSPAVSPSNPQ 5935 KP+LPYS+MFI SP N +RR H+VVNL YFD FIM+VI SSIALAAEDPV+E S +N IL +FDYAFTGVFT+EM+LKI+DLG+ILHPGSY R+ WNI+DA VVICA V+F G + GSSA +NL+TIKSLRVLRVLRPLKTI RVPKLKAVFDCVV+SLKNV NILIVYILFQFIF+VI VQLF GKFFYC D SK + C+G +F Y P+ + R+W+ FH+DN+ AMLTLF V TGEGWP VL++SM +T D GPI ++R EM+IFYIV+FIVFPFFFVNIFVALIIITFQEQGE EL D ++DKNQK CIDF I +PL RYMPK++ T KY+VWR+VVSTPFEYFIM++I NTL+LMMKY+ + Y +L ++N FT MFS+E VLKI+ FG KN+F+DPWNIFD ITV+GSI D L E DS+ +++GFLRLFRAARLIKLLRQGYTIRILLWTF+QSFKALPYVCLLIAMLFFIY+IIGMQVFGNIKL + E I RHNNFQ+F G++LLFRCATGE+W IMLAC K C+ D E CGS Y YFVSFIF CSFLMLNLFVAVIMDNFDYLTRDSSILG HHLDE++R+WAEYDP A G+IH++EMY+ML+NM+PP+GFG KCP RLAY+KLIRMNMP+D+ V FTTTLFALIRE+L+IKM E MD DMELR+TI +WP+QAKK LNL+VPP +L K++VGKIYAG+LI+E+WR+ + Q P + ++ ++ +E + D H+Y + +RR LR P RG + I+ D+ + S + T PR + PR P S S + R+ +P +S PT G + +RS + SP+ Q Sbjct: 741 KPMLPYSSMFILSPTNPIRRGAHWVVNLPYFDFFIMVVISMSSIALAAEDPVRENSRRNKILNYFDYAFTGVFTIEMLLKIVDLGVILHPGSYLREFWNIMDAVVVICAAVSF---------GFDMSGSSAGQNLSTIKSLRVLRVLRPLKTIKRVPKLKAVFDCVVNSLKNVVNILIVYILFQFIFSVIGVQLFNGKFFYCTDESKHTSAECQGSYFKYEEDELLPKQELRVWKPRAFHYDNVAAAMLTLFAVQTGEGWPQVLQHSMAATYEDRGPIQNFRIEMSIFYIVYFIVFPFFFVNIFVALIIITFQEQGEAELQDGEIDKNQKSCIDFTIGARPLERYMPKNRNTFKYKVWRIVVSTPFEYFIMMLIVFNTLLLMMKYHNQGDM----------------YEKSLKYINMGFTGMFSVETVLKIIGFGVKNFFKDPWNIFDLITVLGSIVDALWMEFGHDSNSINVGFLRLFRAARLIKLLRQGYTIRILLWTFVQSFKALPYVCLLIAMLFFIYAIIGMQVFGNIKLGTVENSITRHNNFQSFIQGVMLLFRCATGEAWPNIMLACLKGKACDDDAEKAPGEYCGSTLAYAYFVSFIFFCSFLMLNLFVAVIMDNFDYLTRDSSILGAHHLDEFVRIWAEYDPNATGKIHYTEMYDMLKNMDPPLGFGNKCPNRLAYKKLIRMNMPLDDELRVQFTTTLFALIRENLSIKMRAPEEMDQADMELRETITNIWPLQAKKMLNLLVPPSDQLNKGKLSVGKIYAGFLILESWRSTRFGQLDS--GMPMLELQDASRHPSQESLTG--------------------------ADAGHLHPGHSY---MNGHRRSPSLRHNGSPLARSPSPRRRGHQYIHHDIGFSDTVSNVVEMVKET----RHPRHGNSHPRYPRGSWSASTSPARSPSPSRYGGHLSRSKRTQLPYPTYG---TTSLCQRSRSPSPARLQ 1654 HSP 2 Score: 729.554 bits (1882), Expect = 0.000e+0 Identity = 431/675 (63.85%), Postives = 512/675 (75.85%), Query Frame = 2 Query: 701 SLFIFSEENVIRKYAKIIIEWGPFEYMVLLTILANCIVLSMERHLPKKDKTLLAGQLELTEKYFLGIFCVEALLKIVALGFCCHKEAYLRNVWNIMDFVVVVTGFLMMFLNIDNHSDSSTVDLRTLRAVRVLRPLKLVAGFPSLQVVLKSIIRAMAPLLQIGLLVLFAITIFAIIGLEFYSGAFHYTCFK-ANSDKLPLPIPTEKSLVPCSNSKN--GSGLGAYTCPEDYQ-CKAYWEGPNYGITSFDNIGYAMLTVFQCITMEGWTDIMYHTNDAIGNRFNWLYFVPLIILGSFFMLNLVLGVLSGXXXXXXXXXXXXXXXLKLRRQQQTEKEFNGYMEWIQKAEEVLLNEATTTSEDKMRIIAARRRAEKQKYKLLGKNQSIPDFEYEDTELYSETKSMKGNIFIRSYAGIRRRRKERCTSFWRTEKHFRFSVRRLVKSQPFYWAVIILVFFNTVCVAIEHYEQGKWLTLFLNYAEYVFLCLFMMEMMIKMYGLSIRVYFQSSFNIFDCVVIAGSLFEIIYGIFVQDSSFGLSVLRALRLLRIFKVTRYWAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXGMQLFGGEFNFEEGKPPQNFDTFVKALLTVFQILTGEDWNTVMYNGIQSKGGVKERGTVFSIYFVLLVVFGNYTLLNVFLAIAVDNLAN 2713 SLFI +E+N IRKY + IIEW PFEY VLLTI+ANC+VL++E HLP DKT+LA +LE TE YFL IFCVEA LKI+ALG HK +YLRN+WNIMDF VVVTGF+ + I VDLRTLRA+RVLRPLKLV+G PSLQVVLKSII+AMAPLLQIGLLVLFAI IFAIIGLEFYSGA H TC+ + +KL + +S PC N+ N G++ C C WEGPN GITSFDNIG+AMLTVFQCITMEGWT I+Y TNDA+G+ FNW+YFVPLI++GSFFMLNLVLGVLSGEF+ ER RVE+R F K R + + Y++WI +AEEV+L E TT E+KM I+ ARRR ++ KL +S + DTE + + ++++ R + + CT FWR EK FRF +R VK+Q FYW VI+LVF NTVCVA+EHY Q +LT FL YAE++FL LFM EM IKMY L R+YF+SSFN FDCVVI+GS+FE+I+ V+ SFGLSVLRALRLLRIFKVT+YW+SLRNLV+SLLNSMRSIISLLFLLFLFILIFALLGMQLFGG+FN G P NF+TF ALLTVFQILTGEDWN VMY GI S+GG ++G ++SIYF++LV+FGNYTLLNVFLAIAVDNLAN Sbjct: 17 SLFILTEDNPIRKYTRFIIEWPPFEYAVLLTIIANCVVLALEEHLPGGDKTVLAQKLEKTEAYFLCIFCVEASLKILALGLVLHKHSYLRNIWNIMDFFVVVTGFMTQYPQI-----GPEVDLRTLRAIRVLRPLKLVSGIPSLQVVLKSIIKAMAPLLQIGLLVLFAIVIFAIIGLEFYSGALHKTCYSLEDPNKL---VKEGESETPC-NTDNILEKATGSFVCNNTTSMCLEKWEGPNSGITSFDNIGFAMLTVFQCITMEGWTAILYWTNDALGSAFNWIYFVPLIVIGSFFMLNLVLGVLSGEFSNERNRVERRMEFQKCRFRAMFQTAMVSYLDWITQAEEVILAEERTTEEEKMHIMEARRRNAAKRKKLKSLGKS----KSTDTEEEEAEEDYGDDGYLKT----RSKPQGSCTGFWRAEKRFRFWIRHTVKTQWFYWFVIVLVFLNTVCVAVEHYGQPSFLTEFLYYAEFIFLGLFMSEMFIKMYALGPRIYFESSFNRFDCVVISGSIFEVIWSE-VKGGSFGLSVLRALRLLRIFKVTKYWSSLRNLVISLLNSMRSIISLLFLLFLFILIFALLGMQLFGGQFNLPGGTPETNFNTFPIALLTVFQILTGEDWNEVMYQGIISQGGA-QKGMIYSIYFIVLVLFGNYTLLNVFLAIAVDNLAN 672 HSP 3 Score: 117.087 bits (292), Expect = 1.558e-25 Identity = 79/275 (28.73%), Postives = 136/275 (49.45%), Query Frame = 2 Query: 701 SLFIFSEENVIRKYAKIIIEWGPFEYMVLLTILANCIVLSMERHLPKKDKTLLAGQLELTEKYFLGIFCVEALLKIVALGFCCHKEAYLRNVWNIMDFVVVVTGFLMMFLNIDNHSDSSTVD-LRTLRAVRVLRPLKLVAGFPSLQVVLKSIIRAMAPLLQIGLLVLFAITIFAIIGLEFYSGAFHYTCFKANSDKLPLPIPTEKSLVPCSNSKNGSGLGAYTCPEDYQCKAYWEGPNYGITSF--DNIGYAMLTVFQCITMEGWTDIMYHTNDA 1516 S+FI S N IR+ A ++ F++ +++ I + I L+ E P ++ + L + F G+F +E LLKIV LG H +YLR WNIMD VVV+ + ++ S + +++LR +RVLRPLK + P L+ V ++ ++ ++ I ++ + IF++IG++ ++G F Y +D+ S + G+Y E+ + E + +F DN+ AMLT+F T EGW ++ H+ A Sbjct: 748 SMFILSPTNPIRRGAHWVVNLPYFDFFIMVVISMSSIALAAED--PVRENSRRNKILNYFDYAFTGVFTIEMLLKIVDLGVILHPGSYLREFWNIMDAVVVICAAVSFGFDMSGSSAGQNLSTIKSLRVLRVLRPLKTIKRVPKLKAVFDCVVNSLKNVVNILIVYILFQFIFSVIGVQLFNGKFFYC-----TDE--------------SKHTSAECQGSYFKYEEDELLPKQELRVWKPRAFHYDNVAAAMLTLFAVQTGEGWPQVLQHSMAA 1001 HSP 4 Score: 112.849 bits (281), Expect = 3.541e-24 Identity = 78/288 (27.08%), Postives = 140/288 (48.61%), Query Frame = 2 Query: 3053 PETIQRKPVLPYSAMFIFSPLNSLRRFCHFVVNLRYFDLFIMIVICASSIALAAED--PVKEKSLKNNILEFFDYAFTGVFTVEMILKIIDLGIILHPGSYCRDLWNILDATVVICALVAFIMGQKPSPTGNKLRGSSAKNLNTIKSLRVLRVLRPLKTINRVPKLKAVFDCVVSSLKNVFNILIVYILFQFIFAVIAVQLFQGKF----FYCNDASKSSRE-----------TCRGYFFDYAGRSTPETKKRLWQHHD---FHFDNILYAMLTLFTVTTGEGWPTVL 3856 P+ + P +++FI + N +R++ F++ F+ +++ I A+ + LA E+ P +K++ LE + F +F VE LKI+ LG++LH SY R++WNI+D VV+ M Q P G ++ +++LR +RVLRPLK ++ +P L+ V ++ ++ + I ++ + IFA+I ++ + G + D +K +E + +T W+ + FDNI +AMLT+F T EGW +L Sbjct: 4 PKKEENPPGGGPTSLFILTEDNPIRKYTRFIIEWPPFEYAVLLTIIANCVVLALEEHLPGGDKTVLAQKLEKTEAYFLCIFCVEASLKILALGLVLHKHSYLRNIWNIMDFFVVVTGF----MTQYPQ-IGPEV---------DLRTLRAIRVLRPLKLVSGIPSLQVVLKSIIKAMAPLLQIGLLVLFAIVIFAIIGLEFYSGALHKTCYSLEDPNKLVKEGESETPCNTDNILEKATGSFVCNNTTSMCLEKWEGPNSGITSFDNIGFAMLTVFQCITMEGWTAIL 277 HSP 5 Score: 98.5969 bits (244), Expect = 6.419e-20 Identity = 72/259 (27.80%), Postives = 140/259 (54.05%), Query Frame = 2 Query: 1979 FRFSVRRLVKSQPFYWAVIILVFFNTVCVAIEHYEQGKWLTLFLNYAEYVFLCLFMMEMMIKMYGLSIRVYFQSSFNIFDCVVIAGSLFEIIYGIFVQDS-SFGLSVLRALRLLRIFKVTRYWAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXGMQLFGGEFNFEEGKPP------QNFDTFVKALLTVFQILTGEDWNTVMYNGIQSKG---------GVKERGTVFSIYFVLLVVFGNYTLLNVFLAIAVDNL 2707 F++ V R+V S PF + +++L+ FNT+ + ++++ QG L Y F +F +E ++K+ G ++ +F+ +NIFD + + GS+ + ++ F DS S + LR R R+ K+ R ++R L+ + + S +++ + L+ + I+A++GMQ+FG N + G NF +F++ ++ +F+ TGE W +M ++ K G T+ YFV + F ++ +LN+F+A+ +DN Sbjct: 1084 FKYKVWRIVVSTPFEYFIMMLIVFNTLLLMMKYHNQGDMYEKSLKYINMGFTGMFSVETVLKIIGFGVKNFFKDPWNIFDLITVLGSIVDALWMEFGHDSNSINVGFLRLFRAARLIKLLRQGYTIRILLWTFVQSFKALPYVCLLIAMLFFIYAIIGMQVFG---NIKLGTVENSITRHNNFQSFIQGVMLLFRCATGEAWPNIMLACLKGKACDDDAEKAPGEYCGSTLAYAYFVSFIFFCSFLMLNLFVAVIMDNF 1339 HSP 6 Score: 78.1814 bits (191), Expect = 1.256e-13 Identity = 70/293 (23.89%), Postives = 131/293 (44.71%), Query Frame = 2 Query: 767 PFEYMVLLTILANCIVLSMERHLPKKDKTLLAGQLELTEKYFLGIFCVEALLKIVALGFCCHKEAYLRNVWNIMDFVVVVTGFLMMFLNIDNHSDSSTVDLRTLRAVRVLRPLKLVAGFPSLQVVLKSIIRAMAPLLQIGLLVLFAITIFAIIGLEFYSGAFHYTCFKANSDKLPLPIPTEKSLVPCSNSKNGSGLGAYTCPEDYQCKAYWEGPNYGITSFDNIGYAMLTVFQCITMEGWTDIMYHT-------NDA-------IGNRFNWLYFVPLIILGSFFMLNLVLGVL 1603 PFEY +++ I+ N ++L M+ H + L+ F G+F VE +LKI+ G + + ++ WNI D + V+ G ++ L ++ DS+++++ LR R R +KL+ +++++L + +++ L + LL+ I+AIIG++ + N K G+ + T ++Q ++ +G ++ +F+C T E W +IM +DA G+ + YFV I SF MLNL + V+ Sbjct: 1096 PFEYFIMMLIVFNTLLLMMKYH---NQGDMYEKSLKYINMGFTGMFSVETVLKIIGFGV----KNFFKDPWNIFDLITVL-GSIVDALWMEFGHDSNSINVGFLRLFRAARLIKLLRQGYTIRILLWTFVQSFKALPYVCLLIAMLFFIYAIIGMQVF-----------------------------GNIKLGTVENSITRHNNFQ--SFIQG--------------VMLLFRCATGEAWPNIMLACLKGKACDDDAEKAPGEYCGSTLAYAYFVSFIFFCSFLMLNLFVAVI 1335 HSP 7 Score: 72.4034 bits (176), Expect = 6.274e-12 Identity = 80/307 (26.06%), Postives = 137/307 (44.63%), Query Frame = 2 Query: 4040 DKNQKQCIDFAINEKPLCRYMPKDKTTIKYRVW-RLVVSTP-FEYFIMVMIALNTLILMMKYYREEKKASSAATHDREQQAYLN---YCNTLIFLNSAFTVMFSIECVLKIMAFGPKNYFRDPWNIFDFITVIGSITDVLVSELQDXXXXXXXXXXXXXXXXXXXXXXQGYTIRILLWTFIQSFKALPYVCLLIAMLFFIYSIIGMQVFGNIKLISEYQIN-----RHNNFQTFTNGLLLLFRCATGESWQEIMLACDNNKPCEKDIENTNNFDCGSNFTYIYFVSFIFLCSFLMLNLFVAVIMDNF 4930 K Q C F EK ++R W R V T F +F++V++ LNT+ + +++Y Q ++L Y IFL +F E +K+ A GP+ YF +N FD + + GSI +V+ SE++ SF L ++R L+ + + S +++ + L+ + I++++GMQ+FG Q N NF TF LL +F+ TGE W E+M + I + G ++ IYF+ + ++ +LN+F+A+ +DN Sbjct: 414 SKPQGSCTGFWRAEK-------------RFRFWIRHTVKTQWFYWFVIVLVFLNTVCVAVEHY--------------GQPSFLTEFLYYAEFIFLG-----LFMSEMFIKMYALGPRIYFESSFNRFDCVVISGSIFEVIWSEVKGGSFGLSVLRALRLLRIFKVTKYWS-SLRNLVISLLNSMRSIISLLFLLFLFILIFALLGMQLFGG-------QFNLPGGTPETNFNTFPIALLTVFQILTGEDWNEVMY---------QGIISQGGAQKGMIYS-IYFIVLVLFGNYTLLNVFLAIAVDNL 670
BLAST of Voltage dependent L type calcium channel subunit vs. Ensembl Zebrafish
Match: cacna1sa (calcium channel, voltage-dependent, L type, alpha 1S subunit, a [Source:ZFIN;Acc:ZDB-GENE-090514-1]) HSP 1 Score: 1132.09 bits (2927), Expect = 0.000e+0 Identity = 714/1657 (43.09%), Postives = 985/1657 (59.44%), Query Frame = 2 Query: 623 KTTSMRSLAKRTINLSFPGMQTSTSKSLFIFSEENVIRKYAKIIIEWGPFEYMVLLTILANCIVLSMERHLPKKDKTLLAGQLELTEKYFLGIFCVEALLKIVALGFCCHKEAYLRNVWNIMDFVVVVTGFLMMFLNIDNH--------SDSSTVDLRTLRAVRVLRPLKLVAGFPSLQVVLKSIIRAMAPLLQIGLLVLFAITIFAIIGLEFYSGAFHYTCFKANSDKLPLPIPTEKSLVPCSNSKNGSGLGAYTCP-EDYQCKAYWEGPNYGITSFDNIGYAMLTVFQCITMEGWTDIMYHTNDAIGNRFNWLYFVPLIILGSFFMLNLVLGVLSGXXXXXXXXXXXXXXXLKLRRQQQTEKEFNGYMEWIQKAEEVLLNEATTTSEDKMRIIAARRRAEKQKYKLLGKNQSIPDFEYEDTELYSETKSMKGNIFIRSYAGIRRRRKERCTSFWRTEKHFRFSVRRLVKSQPFYWAVIILVFFNTVCVAIEHYEQGKWLTLFLNYAEYVFLCLFMMEMMIKMYGLSIRVYFQSSFNIFDCVVIAGSLFEIIYGIFVQDSSFGLSVLRALRLLRIFKVTRYWAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXGMQLFGGEFNFEEGKPPQ-NFDTFVKALLTVFQILTGEDWNTVMYNGIQSKGGVKERGTVFSIYFVLLVVFGNYTLLNVFLAIAVDNLANXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSSDNFIGRLPLSIDPPMVQVCPPSPQTANSLISKNFSFDHNQVEVNDKGCLLNTNKPNGKLGMLGHDNTNFNSLESDPVPNKIEPETIQRK--PVLPYSAMFIFSPLNSLRRFCHFVVNLRYFDLFIMIVICASSIALAAEDPVKEKSLKNNILEFFDYAFTGVFTVEMILKIIDLGIILHPGSYCRDLWNILDATVVICALVAFIMGQKPSPTGNKLRGSSAKNLNTIKSLRVLRVLRPLKTINRVPKLKAVFDCVVSSLKNVFNILIVYILFQFIFAVIAVQLFQGKFFYCNDASKSSRETCRGYFFDYAGRSTPE--TKKRLWQHHDFHFDNILYAMLTLFTVTTGEGWPTVLKNSMESTNIDNGPIADYRQEMAXXXXXXXXXXXXXXXXXXXALIIITFQEQGENELIDLDLDKNQKQCIDFAINEKPLCRYMPKDKTTIKYRVWRLVVSTPFEYFIMVMIALNTLILMMKYYREEKKASSAATHDREQQAYLNYCNTLIFLNSAFTVMFSIECVLKIMAFGPKNYFRDPWNIFDFITVIGSITDVLVSEL---------------------------QDXXXXXXXXXXXXXXXXXXXXXXQGYTIRILLWTFIQSFKALPYVCLLIAMLFFIYSIIGMQVFGNIKLISEYQINRHNNFQTFTNGLLLLFRCATGESWQEIMLACDNNKPCEKDIE--NTNNFDCGSNFTYIYFVSFIFLCSFLMLNLFVAVIMDNFDYLTRDSSILGPHHLDEYIRVWAEYDPGAIGRIHHSEMYEMLRNMEPPVGFGKKCPYRLAYRKLIRMNMPVDENGTVNFTTTLFALIRESLNIKMSTAEYMDIKDMELRQTICKMWPVQAKKKLNLIVPPDSELVFHKMTVGKIYAGYLIVENWRAYKNSQEQGPRSSPAVSIKSVTK 5464 + T R ++ L G ++SL + +N RK I+EW PFE ++LLTI ANC+ L++ +P++D LE E FL IF +E LKIVA GF H +AYLRN WNI+DFV+V G + ++ N D++ LRA RVLRPL+LV+G PSLQVV+ SI+++M PL I LLV F +TI+AIIGLE + H TC+ +D + + PC+ + NG C +C+ W GPN GIT FDN+G++MLTV+QCIT +GWTD++Y NDAIG + WLYFV LI+LGSFF+LNLVLGVL GEF KERE+ + + LR +QQ +++ GYMEWI +AE V+ N+ E Q +P + +TE E + +F +R R R + FR R VKS+ FYW VI+LVFFNT+ +A EH++Q LT F + L LF +EM +KMY + + YF S FN FDC V++ + E+I S G+SVLR +RLLRI K+TR+W +L NLV SLLNS+RSI SLL LLFLFI+IFALLGMQ+FGG+FNF + + + NFD F +AL+TVFQILTGE WN VMY+GI + GG G + SIYF++L + GNY LLNVFLAIAVDNLA A+ LT+A++EKA E +R ++ + + L+ + P + + K F+ N E+ D P G D + P P + ++ P+ SA F+F P N R+ CH ++N F I++ I SSI+LAAEDP+ S +N +L + DY FT VFT E++LK+ G LH GS+CR+ +NILD VV +L++ MG + S ++ +K LRVLRVLRPL+ INR LK V CV ++K + NI++V +L F+FA I VQLF+GKF YC D K + E C+G F + + + +RLW + D +FDN+L ML LFTV+T EGWP +L +++S + GP+ + E++IF+IV+ I+ FF +NIFV +I+TFQEQGE E + +LDKNQ+QC+ +A+ +PL Y+PK+ +Y+VW +V S FEY + ++I LNT+ L M++ ++ + A LN FTV+F++E +LK+ AF K YF DPWN+FDF+ V+GSI DV++SE+ ++ +S+ RLFR RL+KLL + IR LLWTFI+SF+ALPYV LLI MLFFIY++IGMQVFG I L+ INR+NNFQTF +LLLFRCATGE W EIML C + C+ E + CGS F +YF+SF LC+FL++NLFVAVIMDNFDYLTRD SILGP HLDE+ ++WAEYDP A GRI H ++ +LR ++PP+GFGK CP+R+A ++LI MNMP++ +GTV F TLFAL+R L IK T + + ELR I K+W + K L+ ++P + ++TVGK YA +LI +++R + QE+ P+ K+ T+ Sbjct: 16 EETLKRKQREKLKKLQATGGNPRPARSLLFLTLKNPFRKACINIVEWKPFEIIILLTIFANCVALAVFMPMPEEDTNNTNSNLESLEYIFLIIFTMECFLKIVAYGFLFHADAYLRNCWNILDFVIVTMGLFTVVVDFINSISGVEAPVEQKGGFDMKALRAFRVLRPLRLVSGVPSLQVVMSSILKSMLPLFHISLLVFFMVTIYAIIGLELFKCKMHKTCYHTGTDIIA--TGDDAQAAPCAQAGNGR-----RCTLNGTECRGDWPGPNNGITHFDNLGFSMLTVYQCITTQGWTDVLYWVNDAIGMEWPWLYFVTLILLGSFFILNLVLGVLCGEFTKEREKSSRSGEYQILRERQQFDEDLKGYMEWITQAE-VMDNDQ-----------------EGQGL--------LPLQDGSETETLYELDILNKLMFY-----VRHAR--------RWNRFFRRKCRVWVKSKLFYWLVILLVFFNTLAIATEHHQQPDSLTNFQDNTNKALLSLFAVEMFLKMYAMGLPSYFMSLFNRFDCFVVSVGILELILVRMDVMSVMGISVLRCIRLLRIIKITRHWTTLSNLVASLLNSVRSIASLLLLLFLFIVIFALLGMQVFGGKFNFPDDRVRRSNFDNFPQALITVFQILTGEGWNYVMYDGIMAHGGPAIPGILVSIYFIILFICGNYILLNVFLAIAVDNLAEAESLTSAQKEKAEEKKRKRLLRENLPDKGEEEKALLAKKLAEQRAKIDGIPTTAKL------KVDEFESNVNEIKD---------PFPPADFPGDDEEEEPEIPLSPRPRPMADLQLKETEVPMPEASAFFLFGPQNKFRKLCHRIINATTFTNIILLFILLSSISLAAEDPIDPMSFRNQVLAYADYVFTSVFTAEIVLKMTTYGAFLHKGSFCRNSFNILDLIVVGVSLLS--MGMESSA------------ISVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIKTIGNIVLVTMLLDFMFACIGVQLFKGKFLYCTDPLKMTAEECQGTFIQHQENALHDMVVSQRLWMNSDLNFDNVLNGMLALFTVSTFEGWPDLLYKAIDSNLENMGPVYNNHIEISIFFIVYLILIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVQYALKARPLRCYIPKNP--YQYQVWYIVTSCYFEYLMFLLIMLNTMCLGMQHCKQSDHITDLADT----------------LNVIFTVLFTVEMILKLGAFKAKGYFGDPWNVFDFVIVVGSIVDVILSEIDAALAAQGGLYCLTGCSEVNPMQAIADSENMSVSITLFRLFRVMRLVKLLNRFEGIRNLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALLDGTIINRNNNFQTFPQAVLLLFRCATGEGWHEIMLGCLYGQRCDPKSEYLPGEEYTCGSGFAILYFMSFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPQHLDEFKKIWAEYDPEATGRIKHLDVVTLLRRIQPPLGFGKFCPHRVACKRLISMNMPLNSDGTVTFNATLFALVRTGLKIK--TEGNFEQANEELRAIIKKIWKRTSMKLLDQVIPALGD---DEVTVGKFYATFLIQDHFRKFMKRQEEYYGYRPSKKNKNTTE 1574
BLAST of Voltage dependent L type calcium channel subunit vs. Ensembl Zebrafish
Match: cacna1sb (calcium channel, voltage-dependent, L type, alpha 1S subunit, b [Source:ZFIN;Acc:ZDB-GENE-051227-1]) HSP 1 Score: 1106.66 bits (2861), Expect = 0.000e+0 Identity = 710/1655 (42.90%), Postives = 987/1655 (59.64%), Query Frame = 2 Query: 677 GMQTSTSKSLFIFSEENVIRKYAKIIIEWGPFEYMVLLTILANCIVLSMERHLPKKDKTLLAGQLELTEKYFLGIFCVEALLKIVALGFCCHKEAYLRNVWNIMDFVVVVTGFLMMFLN-ID-----NHSDSSTVDLRTLRAVRVLRPLKLVAGFPSLQVVLKSIIRAMAPLLQIGLLVLFAITIFAIIGLEFYSGAFHYTCFKANSDKLPLPIPTEKSLVPCSNSKNGSGLGAYTCP-EDYQCKAYWEGPNYGITSFDNIGYAMLTVFQCITMEGWTDIMYHTNDAIGNRFNWLYFVPLIILGSFFMLNLVLGVLSGXXXXXXXXXXXXXXXLKLRRQQQTEKEFNGYMEWIQKAEEVLLNEATTTSEDKMRIIAARRRAEKQK-YKLLGKNQSIPDFEYEDTELYSETKSMKGNIFIRSYAGIRRRRKERCTSFWRTEKHFRFSVRRLVKSQPFYWAVIILVFFNTVCVAIEHYEQGKWLTLFLNYAEYVFLCLFMMEMMIKMYGLSIRVYFQSSFNIFDCVVIAGSLFEIIY---GIFVQDSSFGLSVLRALRLLRIFKVTRYWAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXGMQLFGGEFNFEEGKPPQ--NFDTFVKALLTVFQILTGEDWNTVMYNGIQSKGGVKERGTVFSIYFVLLVVFGNYTLLNVFLAIAVDNLANXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSSDNFIGRLPLSIDPPMVQVCPPSPQTANSLISKNFSFDHNQVEVNDKGCLLNTNKPNGKLGMLGHDNTNFNSLESDPVPNKIEPETIQRK--PVLPYSAMFIFSPLNSLRRFCHFVVNLRYFDLFIMIVICASSIALAAEDPVKEKSLKNNILEFFDYAFTGVFTVEMILKIIDLGIILHPGSYCRDLWNILDATVVICALVAFIMGQKPSPTGNKLRGSSAKNLNTIKSLRVLRVLRPLKTINRVPKLKAVFDCVVSSLKNVFNILIVYILFQFIFAVIAVQLFQGKFFYCNDASKSSRETCRGYFFDYAGRSTPETK--KRLWQHHDFHFDNILYAMLTLFTVTTGEGWPTVLKNSMESTNIDNGPIADYRQEMAXXXXXXXXXXXXXXXXXXXALIIITFQEQGENELIDLDLDKNQKQCIDFAINEKPLCRYMPKDKTTIKYRVWRLVVSTPFEYFIMVMIALNTLILMMKYYREEKKASSAATHDREQQAYLNYCNTLIFLNSAFTVMFSIECVLKIMAFGPKNYFRDPWNIFDFITVIGSITDVLVSELQ---------------------------DXXXXXXXXXXXXXXXXXXXXXXQGYTIRILLWTFIQSFKALPYVCLLIAMLFFIYSIIGMQVFGNIKLISEYQINRHNNFQTFTNGLLLLFRCATGESWQEIMLACDNNKPCE--KDIENTNNFDCGSNFTYIYFVSFIFLCSFLMLNLFVAVIMDNFDYLTRDSSILGPHHLDEYIRVWAEYDPGAIGRIHHSEMYEMLRNMEPPVGFGKKCPYRLAYRKLIRMNMPVDENGTVNFTTTLFALIRESLNIKMSTAEYMDIKDMELRQTICKMWPVQAKKKLNLIVPPDSELVFHKMTVGKIYAGYLIVENWRAYKNSQEQ----GPRSSPAVSIKSVTKPVVKEEKSA 5491 G ++LF F N RK I+EW PFE ++LLTI ANC+ L++ +P++D LE E FL IF +E LKI+A G H+ AYLRN WNI+DFV+V G + ++ ID D++ LRA RVLRPL+LV+G PSLQVV+ S++++M PL I LLV F +TI+AI+GLE + H TC+ ++ + L + S PC+ + NG C +C+ W GPN+GIT FDN G+AMLTVFQCIT E WTD++Y NDA+GN + W+YF+ LI+LGSFF+LNLVLGVLSGEF KERE+ R + LR +QQ +++ GYMEWI A E D M ++ +E YK+ G N+ + Y + + NI IR +C + VKS+ F W V+I+V NT+ +A EH+ Q + LT F + A + L F +EM++KMY R YF S FN FDC V+ + EII GI + G+SV+R +RLLR+FK+T+YW SL NLV+SLLNS++SI SLL LLFLFI+IFALLGMQ+FGG+FNF + +P Q NFD F +AL++VFQ+LTGE+W+T+MYNGI + GG K G + SIYF++L V GN+ LLNVFLAIAVDNLA A+ L AA++E+A E R L + + + + + Q P TA I + F+ N EV D P G D + P P + ++ P+ S+ FIF P N R+ CH ++N F I++ I SSI+LAAEDP+ S +N +L + D FT VFT+E++LK+ G LHPGS+CR+ +NILD VV +L++ G + ++ +K LRVLRVLRPL+ INR LK V C+ ++K + NI++V +L F+F+ I VQLF+G FYC D + + E C+G F + S +T+ +R W + DF+FDN+L ML LFT++T EGWP +L +++S ++D GP+ + R ++IF+I++ I+ FF +NIFV +I+TFQ QGE E + +LDKNQ+QC+ +A+ +PL Y+P++ +YRVW LV S FEY + +I LNTL L M+Y + + + + LN FTV+F+ E ++K++AF K YF DPWN+FDF+ VIGSI DV++SE+ ++ LS+ F RLFR RLIKLL + IR LLWTFI+SF+ALP+V LLI MLFFIY++IGMQ+FG I L+ +INR+NNFQTF +LLLFR ATGE W +IMLA K C+ D + CGS+ YF+SF LC+FL++NLFVA+IMDNFDYLT D SILGPHHLDE+ ++W EYDP A GRI H ++ +LR ++PP+GFGK CP+ A ++LI MNMP++ +GTV F TLFAL+R +L IK T + + ELR I +W + K L+ ++PP E ++TVGK YA +LI E++R + QE+ P A IK+ + + EE++A Sbjct: 45 GGNPRPPRTLFFFKLRNPFRKACTNIVEWKPFEIIILLTIFANCVALAVFLPMPEEDTNNTNLTLESLEYIFLVIFTLECFLKIIAYGLLFHEGAYLRNCWNILDFVIVFMGLFTLVVDTIDTITGVQKEKGGGFDMKALRAFRVLRPLRLVSGVPSLQVVMSSVLKSMLPLFHILLLVFFMVTIYAIMGLELFKCKMHKTCYYQGTNIIALRENEKPS--PCAQAGNGR-----RCTINGTECRDGWPGPNFGITHFDNFGFAMLTVFQCITTESWTDVLYWINDAMGNDWPWIYFLSLIMLGSFFILNLVLGVLSGEFTKEREKSRSRGEWQVLRERQQMDEDLKGYMEWITHA------EVMDGDSDAMLLLRKDTGSETDSLYKMEGINKVV----------YFYRLARRWNIVIR----------RKCHGW--------------VKSKSFNWWVLIVVLLNTLVIATEHHNQTEGLTNFQDTANVILLACFTIEMIMKMYAFGPRSYFMSIFNRFDCFVVTIGILEIILVGSGIM---TPLGISVMRCIRLLRLFKLTKYWTSLNNLVVSLLNSVKSIASLLLLLFLFIVIFALLGMQVFGGKFNFPD-RPIQRSNFDNFPQALISVFQVLTGEEWDTIMYNGIMAHGGPKSPGILVSIYFIILYVCGNFVLLNVFLAIAVDNLAEAESLAAAQKERAEERARKKLMKPLPEKTEEEKALMAKRLMESR----QKTEGMPTTAKLKIDE---FESNVNEVKD---------PFPPADFPGDDEEEEPEIPISPRPRPMADLQLKETVVPMPEASSFFIFGPQNKFRKLCHRIINHTTFTNIILLFILLSSISLAAEDPIDPHSFRNKVLAYADIVFTTVFTIEIVLKMTVYGAFLHPGSFCRNSFNILDLIVVAVSLLSM--------------GMESSTISVVKILRVLRVLRPLRAINRAKGLKHVVQCMFVAIKTIGNIVLVTMLLDFMFSCIGVQLFKGTLFYCTDPLQKTAEQCQGTFLKHVQNSLHDTEIHQRRWVNSDFNFDNVLNGMLALFTISTFEGWPEILYKAIDSYDVDTGPLYNNRVGISIFFIIYIIIIAFFMMNIFVGFVIVTFQRQGEQEYKNCELDKNQRQCVQYALKARPLKCYIPENPH--QYRVWYLVTSCYFEYLMFFLIMLNTLSLGMQYCNQPFYITKLSDN----------------LNVIFTVLFTGEMIVKLIAFKAKGYFGDPWNVFDFVIVIGSIVDVVLSEVDRTLEASGGLWCLHGCSEVDPMQAIAEAENVKLSITFFRLFRVLRLIKLLNRSEGIRNLLWTFIKSFQALPHVGLLIVMLFFIYAVIGMQMFGKIALVDGTEINRNNNFQTFPQAVLLLFRVATGEQWPKIMLASMYGKLCDPKSDYGPGEEYTCGSSIAVCYFLSFYMLCAFLVINLFVAIIMDNFDYLTHDWSILGPHHLDEFKKIWGEYDPEATGRIKHLDVVTLLRRIQPPLGFGKFCPHHAACKRLISMNMPLNSDGTVTFNATLFALVRTALKIK--TEGNFEQANEELRAIIKSIWKRTSMKLLDQVIPPIGE---DEVTVGKFYATFLIQEHFRKFMQRQEELYGYRPTKKNADEIKAGLRSI--EEEAA 1593
BLAST of Voltage dependent L type calcium channel subunit vs. Ensembl Zebrafish
Match: cacna1bb (calcium channel, voltage-dependent, N type, alpha 1B subunit, b [Source:ZFIN;Acc:ZDB-GENE-090514-4]) HSP 1 Score: 920.998 bits (2379), Expect = 0.000e+0 Identity = 486/801 (60.67%), Postives = 619/801 (77.28%), Query Frame = 2 Query: 3071 KPVLPYSAMFIFSPLNSLRRFCHFVVNLRYFDLFIMIVICASSIALAAEDPVKEKSLKNNILEFFDYAFTGVFTVEMILKIIDLGIILHPGSYCRDLWNILDATVVICALVAFIMGQKPSPTGNKLRGSSAKNLNTIKSLRVLRVLRPLKTINRVPKLKAVFDCVVSSLKNVFNILIVYILFQFIFAVIAVQLFQGKFFYCNDASKSSRETCRGYFFDYAGRSTPETKKRLWQHHDFHFDNILYAMLTLFTVTTGEGWPTVLKNSMESTNIDNGPIADYRQEMAXXXXXXXXXXXXXXXXXXXALIIITFQEQGENELIDLDLDKNQKQCIDFAINEKPLCRYMPKDKTTIKYRVWRLVVSTPFEYFIMVMIALNTLILMMKYYREEKKASSAATHDREQQAYLNYCNTLIFLNSAFTVMFSIECVLKIMAFGPKNYFRDPWNIFDFITVIGSITDVLVSELQDXXXXXXXXXXXXXXXXXXXXXXQGYTIRILLWTFIQSFKALPYVCLLIAMLFFIYSIIGMQVFGNIKLISE-YQINRHNNFQTFTNGLLLLFRCATGESWQEIMLACDNNKPCEKDIENT-NNFDCGSNFTYIYFVSFIFLCSFLMLNLFVAVIMDNFDYLTRDSSILGPHHLDEYIRVWAEYDPGAIGRIHHSEMYEMLRNMEPPVGFGKKCPYRLAYRKLIRMNMPVDENGTVNFTTTLFALIRESLNIKMSTAEYMD-IKDMELRQTICKMWPVQAKKKLNLIVPPD----SELVFHKMTVGKIYAGYLIVENWRAYKNSQEQGPRSSPAVSIK 5452 K +LPYS+MF+F P N +RR CH+VVNLRYF++ I+ VI SSIALAAEDPV+ + +N++L++ DY FTGVFT EM++K+IDLG++LHPGSY RDLWNILD VV ALVAF G+ K++NTIKSLRVLRVLRPLKTI R+PKLKAVFDCVV+SLKNV NILIVYILF FIFAVIAVQLF+GKFF+C D SK+ + CRG F +Y T+ R W+ +DFH+DN+L+A LTLFTV+TGEGWP VLK+S+++T D GP YR E +IFY+V+FIVFPFFFVNIFVALIIITFQEQG+ + + L+KN++ CIDFAIN KPL RYMP+DK + +Y++W+ VVSTPFEY I+ MIA+NT++LMMK++ K Y + L +LN FT +F++ECVLK++AFGP NY ++ WNIFDF+TV+GSITD+LV+E++D ++L FLRLFRAARLIKLLRQGYTIRILLWTF+QSFKALPYVCLLIAMLFFIY+IIGMQVFGNI L +E IN HNNF+TF L+LLFR ATGE+W EIMLAC + + C DIE+ + +CGS+F Y YFVSFIFLCSFLMLNLFVAVIMDNF+YLTRD+SILGPHHLDE+IRVWAEYDP A GR+ + +MYEMLR+M PP+G GKKCP R+AY++L+RMNMP+ E+ TV+FT+TL ALIR +L IK+++ I D ELR+ I K+WP + K ++L+V P ++L ++++TVGK+YA +I + ++ + + Q +++P K Sbjct: 1064 KHILPYSSMFVFGPTNPVRRLCHYVVNLRYFEMCILTVITMSSIALAAEDPVQAHAPRNDVLKYLDYVFTGVFTFEMVIKMIDLGLLLHPGSYFRDLWNILDFIVVSGALVAFACS-----------GTKGKDINTIKSLRVLRVLRPLKTIKRLPKLKAVFDCVVNSLKNVLNILIVYILFMFIFAVIAVQLFKGKFFHCTDESKALEKDCRGQFLEYGSDGVAMTQPREWKKYDFHYDNVLWAFLTLFTVSTGEGWPLVLKHSVDATYEDQGPSPGYRMETSIFYVVYFIVFPFFFVNIFVALIIITFQEQGDKAMSECSLEKNERACIDFAINAKPLTRYMPQDKNSYQYKMWKFVVSTPFEYSILTMIAINTVVLMMKFHGAPKP----------------YEDMLKWLNIIFTALFTLECVLKVIAFGPLNYLKEAWNIFDFVTVLGSITDILVTEIKD-KRINLSFLRLFRAARLIKLLRQGYTIRILLWTFVQSFKALPYVCLLIAMLFFIYAIIGMQVFGNIALNNEDSAINIHNNFRTFFQALMLLFRSATGEAWHEIMLACLSERYC--DIESGYSGKECGSDFAYFYFVSFIFLCSFLMLNLFVAVIMDNFEYLTRDASILGPHHLDEFIRVWAEYDPAACGRMSYLDMYEMLRHMSPPLGLGKKCPPRIAYKRLVRMNMPIAEDNTVHFTSTLMALIRTALEIKLASGVLAQRICDAELRKEINKIWPSLSSKTVDLLVTPHKRKFNKLSYNELTVGKVYAALMIFDYYKQNRAKRLQQQQAAPGTQSK 1834 HSP 2 Score: 706.442 bits (1822), Expect = 0.000e+0 Identity = 422/715 (59.02%), Postives = 524/715 (73.29%), Query Frame = 2 Query: 617 GSKTTSMRSLAKRTINLS-FPGMQT-----STSKSLFIFSEENVIRKYAKIIIEWGPFEYMVLLTILANCIVLSMERHLPKKDKTLLAGQLELTEKYFLGIFCVEALLKIVALGFCCHKEAYLRNVWNIMDFVVVVTGFLMMFLNIDNHSDSSTVDLRTLRAVRVLRPLKLVAGFPSLQVVLKSIIRAMAPLLQIGLLVLFAITIFAIIGLEFYSGAFHYTCFKANSDKLPLPIPTEKSL-VPCSNSKNGSGLGAYTCPEDYQCKAYWEGPNYGITSFDNIGYAMLTVFQCITMEGWTDIMYHTNDAIGNRFNWLYFVPLIILGSFFMLNLVLGVLSGXXXXXXXXXXXXXXXLKLRRQQQTEKEFNGYMEWIQKAEEVLLNEATTTSEDKMRIIAA--RRRAE----KQKYKLLGKNQSIPDFEYEDTELYSETKSMK--GNIFIRSYAGIRRRRKERCTSFWRTEKHFRFSVRRLVKSQPFYWAVIILVFFNTVCVAIEHYEQGKWLTLFLNYAEYVFLCLFMMEMMIKMYGLSIRVYFQSSFNIFDCVVIAGSLFEIIYGIFVQDSSFGLSVLRALRLLRIFKVTRYWAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXGMQLFGGEFNFEEGKPPQNFDTFVKALLTVFQILTGEDWNTVMYNGIQSKGGVKERGTVF-SIYFVLLVVFGNYTLLNVFLAIAVDNLAN 2713 G + +S+A+R ++ + QT + ++SLFIFSE+NVIRKY Y++L TI+ANCIVL++E+HLP DKT ++ +L+ TE YF+GIFC EA +KI+ALGF HK++YLRN WNIMDFVVVVTG L S DLRTLRAVRVLRPLKLV+G PSLQVVLKSI++AM PLLQIGLL+ FAI +FAIIG+EFY G FH+TCFK ++ EK++ PC G+ + +CP C YW+GPN+GIT+FDNI +A+LTVFQCITMEGWTD++YHTNDA GN +NWLYF+PLII+GSFFMLNLVLGVLSGEFAKERERVEKR+ FLKLRRQQQ E+E GY+EWI KAEEVLL E +E+K + A RR+ K+ G+N I E E +++ S+ G+ F R A ++ + + + F R EK RF +RR+VK+Q FYW V+ LV NT+CVAI HY+Q +WLT L AE+VFL LF+ EM +KMYGL R YF SSFN FD VI GS+FE+I+ +SFG+SVLRALRLLRIFKVT+YW SLRNLV+SLLNSM+SIISLLFLLFLFI++FALLGMQLFGG+FNFE+ P NFD+F A++TVFQILTGEDWN VMY+GI+S+GGV RG +F S+YF++L +FGNYTLLNVFLAIAVDNLAN Sbjct: 33 GGQRMYKQSMAQRARTMALYNPKQTKQNCFTVNRSLFIFSEDNVIRKY-----------YLILTTIIANCIVLALEQHLPALDKTPMSERLDDTEPYFIGIFCFEAGIKIIALGFVFHKDSYLRNGWNIMDFVVVVTGILTTV--------GSQFDLRTLRAVRVLRPLKLVSGIPSLQVVLKSIMKAMVPLLQIGLLLFFAIVMFAIIGVEFYMGKFHFTCFKVDTG--------EKAVDYPC-----GAEPPSRSCPVGTNCTEYWKGPNFGITNFDNILFAILTVFQCITMEGWTDVLYHTNDAAGNTWNWLYFIPLIIIGSFFMLNLVLGVLSGEFAKERERVEKRQEFLKLRRQQQIERELTGYLEWICKAEEVLLAEEDQNAEEKSPLDGAWYRRKQNNPVLKRTKSRKGRNDLIS--AEEGDEHFTDISSVAPPGSPFAR--ASLKSSKNDSSSYFRRKEKRIRFFIRRMVKAQSFYWIVLCLVGLNTMCVAIVHYDQPEWLTKALYLAEFVFLGLFLTEMTLKMYGLGPRNYFHSSFNCFDFGVIVGSIFEVIWAAIQPGASFGISVLRALRLLRIFKVTKYWNSLRNLVVSLLNSMKSIISLLFLLFLFIVVFALLGMQLFGGQFNFEDETPTTNFDSFPAAIMTVFQILTGEDWNAVMYHGIESQGGV--RGGMFSSVYFIVLTLFGNYTLLNVFLAIAVDNLAN 709 HSP 3 Score: 119.783 bits (299), Expect = 3.983e-26 Identity = 84/316 (26.58%), Postives = 153/316 (48.42%), Query Frame = 2 Query: 701 SLFIFSEENVIRKYAKIIIEWGPFEYMVLLTILANCIVLSME----RHLPKKDKTLLAGQLELTEKYFLGIFCVEALLKIVALGFCCHKEAYLRNVWNIMDFVVVVTGFLMMFLNIDNHSDSSTVDLRTLRAVRVLRPLKLVAGFPSLQVVLKSIIRAMAPLLQIGLLVLFAITIFAIIGLEFYSGAFHYTCFKANSDKLPLPIPTEKSLVPCSNS--KNGSGLGAYTCPEDYQCKAYWEGPNYGITSFDNIGYAMLTVFQCITMEGWTDIMYHTNDAI--------GNRFNW-LYFVPLIILGSFFMLNLVLGVL 1603 S+F+F N +R+ ++ FE +L I + I L+ E H P+ D L+ + F G+F E ++K++ LG H +Y R++WNI+DF+VV + + D +T+ ++LR +RVLRPLK + P L+ V ++ ++ +L I ++ + + IFA+I ++ + G F + ++ + EK C + GS A T P + W+ ++ +DN+ +A LT+F T EGW ++ H+ DA G R +++V I+ FF +N+ + ++ Sbjct: 1071 SMFVFGPTNPVRRLCHYVVNLRYFEMCILTVITMSSIALAAEDPVQAHAPRNDV------LKYLDYVFTGVFTFEMVIKMIDLGLLLHPGSYFRDLWNILDFIVVSGALVAFACSGTKGKDINTI--KSLRVLRVLRPLKTIKRLPKLKAVFDCVVNSLKNVLNILIVYILFMFIFAVIAVQLFKGKFFHCTDESKA--------LEKD---CRGQFLEYGSDGVAMTQPRE------WKKYDF---HYDNVLWAFLTLFTVSTGEGWPLVLKHSVDATYEDQGPSPGYRMETSIFYVVYFIVFPFFFVNIFVALI 1358 HSP 4 Score: 113.235 bits (282), Expect = 3.346e-24 Identity = 78/277 (28.16%), Postives = 132/277 (47.65%), Query Frame = 2 Query: 3092 AMFIFSPLNSLRRFCHFVVNLRYFDLFIMIVICASSIALAAED--PVKEKSLKNNILEFFDYAFTGVFTVEMILKIIDLGIILHPGSYCRDLWNILDATVVICALVAFIMGQKPSPTGNKLRGSSAKNLNTIKSLRVLRVLRPLKTINRVPKLKAVFDCVVSSLKNVFNILIVYILFQFIFAVIAVQLFQGKF-FYCNDASKSSRETCRGYFFDYAGRSTPETKK--------RLWQHHDF---HFDNILYAMLTLFTVTTGEGWPTVLKNSMESTN 3880 ++FIFS N +R++ I+ I A+ I LA E P +K+ + L+ + F G+F E +KII LG + H SY R+ WNI+D VV+ ++ + Q +++LR +RVLRPLK ++ +P L+ V ++ ++ + I ++ +FA+I V+ + GKF F C + DY + P ++ W+ +F +FDNIL+A+LT+F T EGW VL ++ ++ Sbjct: 67 SLFIFSEDNVIRKY-----------YLILTTIIANCIVLALEQHLPALDKTPMSERLDDTEPYFIGIFCFEAGIKIIALGFVFHKDSYLRNGWNIMDFVVVVTGILTTVGSQ-----------------FDLRTLRAVRVLRPLKLVSGIPSLQVVLKSIMKAMVPLLQIGLLLFFAIVMFAIIGVEFYMGKFHFTCFKVDTGEKAV------DYPCGAEPPSRSCPVGTNCTEYWKGPNFGITNFDNILFAILTVFQCITMEGWTDVLYHTNDAAG 309 HSP 5 Score: 91.6633 bits (226), Expect = 1.310e-17 Identity = 73/253 (28.85%), Postives = 138/253 (54.55%), Query Frame = 2 Query: 1979 FRFSVRRLVKSQPFYWAVIILVFFNTVCVAIEHYEQGKWLTLFLNYAEYVFLCLFMMEMMIKMYGLSIRVYFQSSFNIFDCVVIAGSLFEIIYGIFVQDSSFGLSVLRALRLLRIFKVTRYWAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXGMQLFGG-EFNFEEG--KPPQNFDTFVKALLTVFQILTGEDWNTVM-------YNGIQSKGGVKERGTVFS-IYFVLLVVFGNYTLLNVFLAIAVDN 2704 +++ + + V S PF ++++ ++ NTV + ++ + K L + +F LF +E ++K+ Y + ++NIFD V + GS+ +I+ ++D LS LR R R+ K+ R ++R L+ + + S +++ + L+ + I+A++GMQ+FG N E+ NF TF +AL+ +F+ TGE W+ +M Y I+S KE G+ F+ YFV + ++ +LN+F+A+ +DN Sbjct: 1403 YQYKMWKFVVSTPFEYSILTMIAINTVVLMMKFHGAPKPYEDMLKWLNIIFTALFTLECVLKVIAFGPLNYLKEAWNIFDFVTVLGSITDILV-TEIKDKRINLSFLRLFRAARLIKLLRQGYTIRILLWTFVQSFKALPYVCLLIAMLFFIYAIIGMQVFGNIALNNEDSAINIHNNFRTFFQALMLLFRSATGEAWHEIMLACLSERYCDIESGYSGKECGSDFAYFYFVSFIFLCSFLMLNLFVAVIMDN 1654 HSP 6 Score: 90.1225 bits (222), Expect = 4.248e-17 Identity = 72/292 (24.66%), Postives = 142/292 (48.63%), Query Frame = 2 Query: 4097 YMPKDKTTIKYRVWRLVVSTPFEYFIMVMIALNTLILMMKYYREEKKASSAATHDREQQAYLNYCNTLIFLNSAFTVMFSIECVLKIMAFGPKNYFRDPWNIFDFITVIGSITDVLVSELQDXXXXXXXXXXXXXXXXXXXXXXQGYTIRILLWTFIQSFKALPYVCLLIAMLFFIYSIIGMQVFGNIKLISEYQINRHN-----NFQTFTNGLLLLFRCATGESWQEIMLACDNNKPCEKDIENTNNFDCGSNFTYIYFVSFIFLCSFLMLNLFVAVIMDNF---DYLTRD 4948 Y + + I++ + R+V + F + ++ ++ LNT+ + + +Y + + + A Y +FL +F E LK+ GP+NYF +N FDF ++GSI +V+ + +Q + + LR R R+ K+ + ++R L+ + + S K++ + L+ + +++++GMQ+FG Q N + NF +F ++ +F+ TGE W +M IE+ G F+ +YF+ ++ +LN+F+A+ +DN LT+D Sbjct: 458 YFRRKEKRIRFFIRRMVKAQSFYWIVLCLVGLNTMCVAIVHYDQPEWLTKAL-----------YLAEFVFLG-----LFLTEMTLKMYGLGPRNYFHSSFNCFDFGVIVGSIFEVIWAAIQPGASFGISVLRALRLLRIFKVTKYWNSLRNLVVSLLNSMKSIISLLFLLFLFIVVFALLGMQLFGG-------QFNFEDETPTTNFDSFPAAIMTVFQILTGEDWNAVMY---------HGIESQGGVR-GGMFSSVYFIVLTLFGNYTLLNVFLAIAVDNLANAQELTKD 716 HSP 7 Score: 77.0258 bits (188), Expect = 3.216e-13 Identity = 71/293 (24.23%), Postives = 120/293 (40.96%), Query Frame = 2 Query: 767 PFEYMVLLTILANCIVLSMERH-LPKKDKTLLAGQLELTEKYFLGIFCVEALLKIVALGFCCHKEAYLRNVWNIMDFVVVVTGFLMMFLNIDNHSDSSTVDLRTLRAVRVLRPLKLVAGFPSLQVVLKSIIRAMAPLLQIGLLVLFAITIFAIIGLEFYSGAFHYTCFKANSDKLPLPIPTEKSLVPCSNSKNGSGLGAYTCPEDYQCKAYWEGPNYGITSFDNIGYAMLTVFQCITMEGWTDIMY-------------HTNDAIGNRFNWLYFVPLIILGSFFMLNLVLGVL 1603 PFEY +L I N +VL M+ H PK + +L + F +F +E +LK++A G YL+ WNI DFV V+ + + ++L LR R R +KL+ +++++L + +++ L + LL+ I+AIIG++ + + + E S + N +F A++ +F+ T E W +IM ++ G+ F + YFV I L SF MLNL + V+ Sbjct: 1415 PFEYSILTMIAINTVVLMMKFHGAPKPYEDML----KWLNIIFTALFTLECVLKVIAFG----PLNYLKEAWNIFDFVTVLGSITDILV---TEIKDKRINLSFLRLFRAARLIKLLRQGYTIRILLWTFVQSFKALPYVCLLIAMLFFIYAIIGMQVFGN---------------IALNNEDSAINIHN------------------------------NFRTFFQALMLLFRSATGEAWHEIMLACLSERYCDIESGYSGKECGSDFAYFYFVSFIFLCSFLMLNLFVAVI 1651 HSP 8 Score: 53.1434 bits (126), Expect = 6.746e-6 Identity = 50/207 (24.15%), Postives = 100/207 (48.31%), Query Frame = 2 Query: 3254 LEFFDYAFTGVFTVEMILKIIDLGIILHPGSYCRDLWNILDATVVICALVAFIMGQKPSPTGNKLRGSSAKNLNTIKSLRVLRVLRPLKTINRVPKLKAVFDCVVSSLKNVFNILIVYILFQFIFAVIAVQLFQGKFFYCNDASKSSRETCRGYFFDYAGRSTPETKKRLWQHHDFHFDNILYAMLTLFTVTTGEGWPTVLKNSMES 3874 L ++ F G+F EM LK+ LG P +Y +N D V++ ++ I ++ ++ ++ +++LR+LR+ + K N L+ + +++S+K++ ++L + LF +FA++ +QLF G+F + ++ TP T +FD+ A++T+F + TGE W V+ + +ES Sbjct: 509 LYLAEFVFLGLFLTEMTLKMYGLG----PRNYFHSSFNCFDFGVIVGSIFEVIWA--------AIQPGASFGISVLRALRLLRIFKVTKYWN---SLRNLVVSLLNSMKSIISLLFLLFLFIVVFALLGMQLFGGQFNFEDE--------------------TPTT----------NFDSFPAAIMTVFQILTGEDWNAVMYHGIES 670
BLAST of Voltage dependent L type calcium channel subunit vs. Ensembl Zebrafish
Match: cacna1bb (calcium channel, voltage-dependent, N type, alpha 1B subunit, b [Source:ZFIN;Acc:ZDB-GENE-090514-4]) HSP 1 Score: 920.998 bits (2379), Expect = 0.000e+0 Identity = 486/801 (60.67%), Postives = 619/801 (77.28%), Query Frame = 2 Query: 3071 KPVLPYSAMFIFSPLNSLRRFCHFVVNLRYFDLFIMIVICASSIALAAEDPVKEKSLKNNILEFFDYAFTGVFTVEMILKIIDLGIILHPGSYCRDLWNILDATVVICALVAFIMGQKPSPTGNKLRGSSAKNLNTIKSLRVLRVLRPLKTINRVPKLKAVFDCVVSSLKNVFNILIVYILFQFIFAVIAVQLFQGKFFYCNDASKSSRETCRGYFFDYAGRSTPETKKRLWQHHDFHFDNILYAMLTLFTVTTGEGWPTVLKNSMESTNIDNGPIADYRQEMAXXXXXXXXXXXXXXXXXXXALIIITFQEQGENELIDLDLDKNQKQCIDFAINEKPLCRYMPKDKTTIKYRVWRLVVSTPFEYFIMVMIALNTLILMMKYYREEKKASSAATHDREQQAYLNYCNTLIFLNSAFTVMFSIECVLKIMAFGPKNYFRDPWNIFDFITVIGSITDVLVSELQDXXXXXXXXXXXXXXXXXXXXXXQGYTIRILLWTFIQSFKALPYVCLLIAMLFFIYSIIGMQVFGNIKLISE-YQINRHNNFQTFTNGLLLLFRCATGESWQEIMLACDNNKPCEKDIENT-NNFDCGSNFTYIYFVSFIFLCSFLMLNLFVAVIMDNFDYLTRDSSILGPHHLDEYIRVWAEYDPGAIGRIHHSEMYEMLRNMEPPVGFGKKCPYRLAYRKLIRMNMPVDENGTVNFTTTLFALIRESLNIKMSTAEYMD-IKDMELRQTICKMWPVQAKKKLNLIVPPD----SELVFHKMTVGKIYAGYLIVENWRAYKNSQEQGPRSSPAVSIK 5452 K +LPYS+MF+F P N +RR CH+VVNLRYF++ I+ VI SSIALAAEDPV+ + +N++L++ DY FTGVFT EM++K+IDLG++LHPGSY RDLWNILD VV ALVAF G+ K++NTIKSLRVLRVLRPLKTI R+PKLKAVFDCVV+SLKNV NILIVYILF FIFAVIAVQLF+GKFF+C D SK+ + CRG F +Y T+ R W+ +DFH+DN+L+A LTLFTV+TGEGWP VLK+S+++T D GP YR E +IFY+V+FIVFPFFFVNIFVALIIITFQEQG+ + + L+KN++ CIDFAIN KPL RYMP+DK + +Y++W+ VVSTPFEY I+ MIA+NT++LMMK++ K Y + L +LN FT +F++ECVLK++AFGP NY ++ WNIFDF+TV+GSITD+LV+E++D ++L FLRLFRAARLIKLLRQGYTIRILLWTF+QSFKALPYVCLLIAMLFFIY+IIGMQVFGNI L +E IN HNNF+TF L+LLFR ATGE+W EIMLAC + + C DIE+ + +CGS+F Y YFVSFIFLCSFLMLNLFVAVIMDNF+YLTRD+SILGPHHLDE+IRVWAEYDP A GR+ + +MYEMLR+M PP+G GKKCP R+AY++L+RMNMP+ E+ TV+FT+TL ALIR +L IK+++ I D ELR+ I K+WP + K ++L+V P ++L ++++TVGK+YA +I + ++ + + Q +++P K Sbjct: 1064 KHILPYSSMFVFGPTNPVRRLCHYVVNLRYFEMCILTVITMSSIALAAEDPVQAHAPRNDVLKYLDYVFTGVFTFEMVIKMIDLGLLLHPGSYFRDLWNILDFIVVSGALVAFACS-----------GTKGKDINTIKSLRVLRVLRPLKTIKRLPKLKAVFDCVVNSLKNVLNILIVYILFMFIFAVIAVQLFKGKFFHCTDESKALEKDCRGQFLEYGSDGVAMTQPREWKKYDFHYDNVLWAFLTLFTVSTGEGWPLVLKHSVDATYEDQGPSPGYRMETSIFYVVYFIVFPFFFVNIFVALIIITFQEQGDKAMSECSLEKNERACIDFAINAKPLTRYMPQDKNSYQYKMWKFVVSTPFEYSILTMIAINTVVLMMKFHGAPKP----------------YEDMLKWLNIIFTALFTLECVLKVIAFGPLNYLKEAWNIFDFVTVLGSITDILVTEIKD-KRINLSFLRLFRAARLIKLLRQGYTIRILLWTFVQSFKALPYVCLLIAMLFFIYAIIGMQVFGNIALNNEDSAINIHNNFRTFFQALMLLFRSATGEAWHEIMLACLSERYC--DIESGYSGKECGSDFAYFYFVSFIFLCSFLMLNLFVAVIMDNFEYLTRDASILGPHHLDEFIRVWAEYDPAACGRMSYLDMYEMLRHMSPPLGLGKKCPPRIAYKRLVRMNMPIAEDNTVHFTSTLMALIRTALEIKLASGVLAQRICDAELRKEINKIWPSLSSKTVDLLVTPHKRKFNKLSYNELTVGKVYAALMIFDYYKQNRAKRLQQQQAAPGTQSK 1834 HSP 2 Score: 706.442 bits (1822), Expect = 0.000e+0 Identity = 422/715 (59.02%), Postives = 524/715 (73.29%), Query Frame = 2 Query: 617 GSKTTSMRSLAKRTINLS-FPGMQT-----STSKSLFIFSEENVIRKYAKIIIEWGPFEYMVLLTILANCIVLSMERHLPKKDKTLLAGQLELTEKYFLGIFCVEALLKIVALGFCCHKEAYLRNVWNIMDFVVVVTGFLMMFLNIDNHSDSSTVDLRTLRAVRVLRPLKLVAGFPSLQVVLKSIIRAMAPLLQIGLLVLFAITIFAIIGLEFYSGAFHYTCFKANSDKLPLPIPTEKSL-VPCSNSKNGSGLGAYTCPEDYQCKAYWEGPNYGITSFDNIGYAMLTVFQCITMEGWTDIMYHTNDAIGNRFNWLYFVPLIILGSFFMLNLVLGVLSGXXXXXXXXXXXXXXXLKLRRQQQTEKEFNGYMEWIQKAEEVLLNEATTTSEDKMRIIAA--RRRAE----KQKYKLLGKNQSIPDFEYEDTELYSETKSMK--GNIFIRSYAGIRRRRKERCTSFWRTEKHFRFSVRRLVKSQPFYWAVIILVFFNTVCVAIEHYEQGKWLTLFLNYAEYVFLCLFMMEMMIKMYGLSIRVYFQSSFNIFDCVVIAGSLFEIIYGIFVQDSSFGLSVLRALRLLRIFKVTRYWAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXGMQLFGGEFNFEEGKPPQNFDTFVKALLTVFQILTGEDWNTVMYNGIQSKGGVKERGTVF-SIYFVLLVVFGNYTLLNVFLAIAVDNLAN 2713 G + +S+A+R ++ + QT + ++SLFIFSE+NVIRKY Y++L TI+ANCIVL++E+HLP DKT ++ +L+ TE YF+GIFC EA +KI+ALGF HK++YLRN WNIMDFVVVVTG L S DLRTLRAVRVLRPLKLV+G PSLQVVLKSI++AM PLLQIGLL+ FAI +FAIIG+EFY G FH+TCFK ++ EK++ PC G+ + +CP C YW+GPN+GIT+FDNI +A+LTVFQCITMEGWTD++YHTNDA GN +NWLYF+PLII+GSFFMLNLVLGVLSGEFAKERERVEKR+ FLKLRRQQQ E+E GY+EWI KAEEVLL E +E+K + A RR+ K+ G+N I E E +++ S+ G+ F R A ++ + + + F R EK RF +RR+VK+Q FYW V+ LV NT+CVAI HY+Q +WLT L AE+VFL LF+ EM +KMYGL R YF SSFN FD VI GS+FE+I+ +SFG+SVLRALRLLRIFKVT+YW SLRNLV+SLLNSM+SIISLLFLLFLFI++FALLGMQLFGG+FNFE+ P NFD+F A++TVFQILTGEDWN VMY+GI+S+GGV RG +F S+YF++L +FGNYTLLNVFLAIAVDNLAN Sbjct: 33 GGQRMYKQSMAQRARTMALYNPKQTKQNCFTVNRSLFIFSEDNVIRKY-----------YLILTTIIANCIVLALEQHLPALDKTPMSERLDDTEPYFIGIFCFEAGIKIIALGFVFHKDSYLRNGWNIMDFVVVVTGILTTV--------GSQFDLRTLRAVRVLRPLKLVSGIPSLQVVLKSIMKAMVPLLQIGLLLFFAIVMFAIIGVEFYMGKFHFTCFKVDTG--------EKAVDYPC-----GAEPPSRSCPVGTNCTEYWKGPNFGITNFDNILFAILTVFQCITMEGWTDVLYHTNDAAGNTWNWLYFIPLIIIGSFFMLNLVLGVLSGEFAKERERVEKRQEFLKLRRQQQIERELTGYLEWICKAEEVLLAEEDQNAEEKSPLDGAWYRRKQNNPVLKRTKSRKGRNDLIS--AEEGDEHFTDISSVAPPGSPFAR--ASLKSSKNDSSSYFRRKEKRIRFFIRRMVKAQSFYWIVLCLVGLNTMCVAIVHYDQPEWLTKALYLAEFVFLGLFLTEMTLKMYGLGPRNYFHSSFNCFDFGVIVGSIFEVIWAAIQPGASFGISVLRALRLLRIFKVTKYWNSLRNLVVSLLNSMKSIISLLFLLFLFIVVFALLGMQLFGGQFNFEDETPTTNFDSFPAAIMTVFQILTGEDWNAVMYHGIESQGGV--RGGMFSSVYFIVLTLFGNYTLLNVFLAIAVDNLAN 709 HSP 3 Score: 119.783 bits (299), Expect = 3.983e-26 Identity = 84/316 (26.58%), Postives = 153/316 (48.42%), Query Frame = 2 Query: 701 SLFIFSEENVIRKYAKIIIEWGPFEYMVLLTILANCIVLSME----RHLPKKDKTLLAGQLELTEKYFLGIFCVEALLKIVALGFCCHKEAYLRNVWNIMDFVVVVTGFLMMFLNIDNHSDSSTVDLRTLRAVRVLRPLKLVAGFPSLQVVLKSIIRAMAPLLQIGLLVLFAITIFAIIGLEFYSGAFHYTCFKANSDKLPLPIPTEKSLVPCSNS--KNGSGLGAYTCPEDYQCKAYWEGPNYGITSFDNIGYAMLTVFQCITMEGWTDIMYHTNDAI--------GNRFNW-LYFVPLIILGSFFMLNLVLGVL 1603 S+F+F N +R+ ++ FE +L I + I L+ E H P+ D L+ + F G+F E ++K++ LG H +Y R++WNI+DF+VV + + D +T+ ++LR +RVLRPLK + P L+ V ++ ++ +L I ++ + + IFA+I ++ + G F + ++ + EK C + GS A T P + W+ ++ +DN+ +A LT+F T EGW ++ H+ DA G R +++V I+ FF +N+ + ++ Sbjct: 1071 SMFVFGPTNPVRRLCHYVVNLRYFEMCILTVITMSSIALAAEDPVQAHAPRNDV------LKYLDYVFTGVFTFEMVIKMIDLGLLLHPGSYFRDLWNILDFIVVSGALVAFACSGTKGKDINTI--KSLRVLRVLRPLKTIKRLPKLKAVFDCVVNSLKNVLNILIVYILFMFIFAVIAVQLFKGKFFHCTDESKA--------LEKD---CRGQFLEYGSDGVAMTQPRE------WKKYDF---HYDNVLWAFLTLFTVSTGEGWPLVLKHSVDATYEDQGPSPGYRMETSIFYVVYFIVFPFFFVNIFVALI 1358 HSP 4 Score: 113.235 bits (282), Expect = 3.346e-24 Identity = 78/277 (28.16%), Postives = 132/277 (47.65%), Query Frame = 2 Query: 3092 AMFIFSPLNSLRRFCHFVVNLRYFDLFIMIVICASSIALAAED--PVKEKSLKNNILEFFDYAFTGVFTVEMILKIIDLGIILHPGSYCRDLWNILDATVVICALVAFIMGQKPSPTGNKLRGSSAKNLNTIKSLRVLRVLRPLKTINRVPKLKAVFDCVVSSLKNVFNILIVYILFQFIFAVIAVQLFQGKF-FYCNDASKSSRETCRGYFFDYAGRSTPETKK--------RLWQHHDF---HFDNILYAMLTLFTVTTGEGWPTVLKNSMESTN 3880 ++FIFS N +R++ I+ I A+ I LA E P +K+ + L+ + F G+F E +KII LG + H SY R+ WNI+D VV+ ++ + Q +++LR +RVLRPLK ++ +P L+ V ++ ++ + I ++ +FA+I V+ + GKF F C + DY + P ++ W+ +F +FDNIL+A+LT+F T EGW VL ++ ++ Sbjct: 67 SLFIFSEDNVIRKY-----------YLILTTIIANCIVLALEQHLPALDKTPMSERLDDTEPYFIGIFCFEAGIKIIALGFVFHKDSYLRNGWNIMDFVVVVTGILTTVGSQ-----------------FDLRTLRAVRVLRPLKLVSGIPSLQVVLKSIMKAMVPLLQIGLLLFFAIVMFAIIGVEFYMGKFHFTCFKVDTGEKAV------DYPCGAEPPSRSCPVGTNCTEYWKGPNFGITNFDNILFAILTVFQCITMEGWTDVLYHTNDAAG 309 HSP 5 Score: 91.6633 bits (226), Expect = 1.310e-17 Identity = 73/253 (28.85%), Postives = 138/253 (54.55%), Query Frame = 2 Query: 1979 FRFSVRRLVKSQPFYWAVIILVFFNTVCVAIEHYEQGKWLTLFLNYAEYVFLCLFMMEMMIKMYGLSIRVYFQSSFNIFDCVVIAGSLFEIIYGIFVQDSSFGLSVLRALRLLRIFKVTRYWAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXGMQLFGG-EFNFEEG--KPPQNFDTFVKALLTVFQILTGEDWNTVM-------YNGIQSKGGVKERGTVFS-IYFVLLVVFGNYTLLNVFLAIAVDN 2704 +++ + + V S PF ++++ ++ NTV + ++ + K L + +F LF +E ++K+ Y + ++NIFD V + GS+ +I+ ++D LS LR R R+ K+ R ++R L+ + + S +++ + L+ + I+A++GMQ+FG N E+ NF TF +AL+ +F+ TGE W+ +M Y I+S KE G+ F+ YFV + ++ +LN+F+A+ +DN Sbjct: 1403 YQYKMWKFVVSTPFEYSILTMIAINTVVLMMKFHGAPKPYEDMLKWLNIIFTALFTLECVLKVIAFGPLNYLKEAWNIFDFVTVLGSITDILV-TEIKDKRINLSFLRLFRAARLIKLLRQGYTIRILLWTFVQSFKALPYVCLLIAMLFFIYAIIGMQVFGNIALNNEDSAINIHNNFRTFFQALMLLFRSATGEAWHEIMLACLSERYCDIESGYSGKECGSDFAYFYFVSFIFLCSFLMLNLFVAVIMDN 1654 HSP 6 Score: 90.1225 bits (222), Expect = 4.248e-17 Identity = 72/292 (24.66%), Postives = 142/292 (48.63%), Query Frame = 2 Query: 4097 YMPKDKTTIKYRVWRLVVSTPFEYFIMVMIALNTLILMMKYYREEKKASSAATHDREQQAYLNYCNTLIFLNSAFTVMFSIECVLKIMAFGPKNYFRDPWNIFDFITVIGSITDVLVSELQDXXXXXXXXXXXXXXXXXXXXXXQGYTIRILLWTFIQSFKALPYVCLLIAMLFFIYSIIGMQVFGNIKLISEYQINRHN-----NFQTFTNGLLLLFRCATGESWQEIMLACDNNKPCEKDIENTNNFDCGSNFTYIYFVSFIFLCSFLMLNLFVAVIMDNF---DYLTRD 4948 Y + + I++ + R+V + F + ++ ++ LNT+ + + +Y + + + A Y +FL +F E LK+ GP+NYF +N FDF ++GSI +V+ + +Q + + LR R R+ K+ + ++R L+ + + S K++ + L+ + +++++GMQ+FG Q N + NF +F ++ +F+ TGE W +M IE+ G F+ +YF+ ++ +LN+F+A+ +DN LT+D Sbjct: 458 YFRRKEKRIRFFIRRMVKAQSFYWIVLCLVGLNTMCVAIVHYDQPEWLTKAL-----------YLAEFVFLG-----LFLTEMTLKMYGLGPRNYFHSSFNCFDFGVIVGSIFEVIWAAIQPGASFGISVLRALRLLRIFKVTKYWNSLRNLVVSLLNSMKSIISLLFLLFLFIVVFALLGMQLFGG-------QFNFEDETPTTNFDSFPAAIMTVFQILTGEDWNAVMY---------HGIESQGGVR-GGMFSSVYFIVLTLFGNYTLLNVFLAIAVDNLANAQELTKD 716 HSP 7 Score: 77.0258 bits (188), Expect = 3.216e-13 Identity = 71/293 (24.23%), Postives = 120/293 (40.96%), Query Frame = 2 Query: 767 PFEYMVLLTILANCIVLSMERH-LPKKDKTLLAGQLELTEKYFLGIFCVEALLKIVALGFCCHKEAYLRNVWNIMDFVVVVTGFLMMFLNIDNHSDSSTVDLRTLRAVRVLRPLKLVAGFPSLQVVLKSIIRAMAPLLQIGLLVLFAITIFAIIGLEFYSGAFHYTCFKANSDKLPLPIPTEKSLVPCSNSKNGSGLGAYTCPEDYQCKAYWEGPNYGITSFDNIGYAMLTVFQCITMEGWTDIMY-------------HTNDAIGNRFNWLYFVPLIILGSFFMLNLVLGVL 1603 PFEY +L I N +VL M+ H PK + +L + F +F +E +LK++A G YL+ WNI DFV V+ + + ++L LR R R +KL+ +++++L + +++ L + LL+ I+AIIG++ + + + E S + N +F A++ +F+ T E W +IM ++ G+ F + YFV I L SF MLNL + V+ Sbjct: 1415 PFEYSILTMIAINTVVLMMKFHGAPKPYEDML----KWLNIIFTALFTLECVLKVIAFG----PLNYLKEAWNIFDFVTVLGSITDILV---TEIKDKRINLSFLRLFRAARLIKLLRQGYTIRILLWTFVQSFKALPYVCLLIAMLFFIYAIIGMQVFGN---------------IALNNEDSAINIHN------------------------------NFRTFFQALMLLFRSATGEAWHEIMLACLSERYCDIESGYSGKECGSDFAYFYFVSFIFLCSFLMLNLFVAVI 1651 HSP 8 Score: 53.1434 bits (126), Expect = 6.746e-6 Identity = 50/207 (24.15%), Postives = 100/207 (48.31%), Query Frame = 2 Query: 3254 LEFFDYAFTGVFTVEMILKIIDLGIILHPGSYCRDLWNILDATVVICALVAFIMGQKPSPTGNKLRGSSAKNLNTIKSLRVLRVLRPLKTINRVPKLKAVFDCVVSSLKNVFNILIVYILFQFIFAVIAVQLFQGKFFYCNDASKSSRETCRGYFFDYAGRSTPETKKRLWQHHDFHFDNILYAMLTLFTVTTGEGWPTVLKNSMES 3874 L ++ F G+F EM LK+ LG P +Y +N D V++ ++ I ++ ++ ++ +++LR+LR+ + K N L+ + +++S+K++ ++L + LF +FA++ +QLF G+F + ++ TP T +FD+ A++T+F + TGE W V+ + +ES Sbjct: 509 LYLAEFVFLGLFLTEMTLKMYGLG----PRNYFHSSFNCFDFGVIVGSIFEVIWA--------AIQPGASFGISVLRALRLLRIFKVTKYWN---SLRNLVVSLLNSMKSIISLLFLLFLFIVVFALLGMQLFGGQFNFEDE--------------------TPTT----------NFDSFPAAIMTVFQILTGEDWNAVMYHGIES 670
BLAST of Voltage dependent L type calcium channel subunit vs. Ensembl Zebrafish
Match: cacna1ba (calcium channel, voltage-dependent, N type, alpha 1B subunit, a [Source:ZFIN;Acc:ZDB-GENE-060531-44]) HSP 1 Score: 909.442 bits (2349), Expect = 0.000e+0 Identity = 478/827 (57.80%), Postives = 616/827 (74.49%), Query Frame = 2 Query: 3014 NSLESDPVP----NKIEPETIQRKPVLPYSAMFIFSPLNSLRRFCHFVVNLRYFDLFIMIVICASSIALAAEDPVKEKSLKNNILEFFDYAFTGVFTVEMILKIIDLGIILHPGSYCRDLWNILDATVVICALVAFIMGQKPSPTGNKLRGSSAKNLNTIKSLRVLRVLRPLKTINRVPKLKAVFDCVVSSLKNVFNILIVYILFQFIFAVIAVQLFQGKFFYCNDASKSSRETCRGYFFDYAGRSTPETKKRLWQHHDFHFDNILYAMLTLFTVTTGEGWPTVLKNSMESTNIDNGPIADYRQEMAXXXXXXXXXXXXXXXXXXXALIIITFQEQGENELIDLDLDKNQKQCIDFAINEKPLCRYMPKDKTTIKYRVWRLVVSTPFEYFIMVMIALNTLILMMKYYREEKKASSAATHDREQQAYLNYCNTLIFLNSAFTVMFSIECVLKIMAFGPKNYFRDPWNIFDFITVIGSITDVLVSELQDXXXXXXXXXXXX-XXXXXXXXXXQGYTIRILLWTFIQSFKALPYVCLLIAMLFFIYSIIGMQVFGNIKLISEYQINRHNNFQTFTNGLLLLFRCATGESWQEIMLACDNNKPCEKDIENTNNFDCGSNFTYIYFVSFIFLCSFLMLNLFVAVIMDNFDYLTRDSSILGPHHLDEYIRVWAEYDPGAIGRIHHSEMYEMLRNMEPPVGFGKKCPYRLAYRKLIRMNMPVDENGTVNFTTTLFALIRESLNIKMSTAEYMD-IKDMELRQTICKMWPVQAKKKLNLIVPPDSELVFHKMTVGKIYAGYLIVENWRAYKN----------SQEQGPRSSPAVS 5446 NS++S+ VP N + +P+LP+S+MFIF+P N +RR CH++V+LRYF++ I++VI SSIALAAEDPV+ + +NN+L++ DY FTGVFT EM++K++DLG+ILHPGSY RDLWNILD VV ALVAF G+ K+++TIKSLRVLRVLRPLKTI R+PKLKAVFDCVV+SLKNV NILIVYILF FIFAVIAVQLF+GKFFYC D SK + CRG F DY + + R W+ ++FH+DN+L+A LTLFTV+TGEGWPTVLK+S+++T D GP YR EM+IFY+V+F+VFPFFFVNIFVALIIITFQEQG+ L + L+KN++ CIDFAIN KPL RYMP+++ + +YR+W+ VVS PFEY IM+MIALNT++LMMK++ A Y L +LN FTV+FS+EC+LKI+AFGP NY +D WN+FDF+TV+GSITD+LV+E+ + RAARLIKLLRQGYTIRILLWTF+QSFKALPYVCLLIAMLFFIY+IIGMQVFGNI L + INRHNNF+TF L+LLFR ATGE+W +IML+C + + C+ T +CGS+F Y YFVSFIFLCSFLMLNLFVAVIMDNF+YLTRDSSILGPHHLDE+IRVWAEYDP A GRI + +MYEML +M PP+G GKKCP R+AY++L++MNMP+ ++ +V+FT+TL ALIR +L IK+++ + D EL++ + +WP ++K ++L+V P +++TVGK+YA +I + ++ + ++ GP S VS Sbjct: 1124 NSIDSETVPMTEKNLEDLNQSSIRPILPFSSMFIFNPTNPVRRLCHYIVSLRYFEMCILVVIAMSSIALAAEDPVQANAPRNNVLKYLDYVFTGVFTFEMVIKMVDLGLILHPGSYFRDLWNILDFIVVSGALVAF-----------AFSGTKGKDISTIKSLRVLRVLRPLKTIKRLPKLKAVFDCVVNSLKNVLNILIVYILFMFIFAVIAVQLFKGKFFYCTDESKGLEKDCRGLFLDY-DKDDVTAQPREWKKYEFHYDNVLWAFLTLFTVSTGEGWPTVLKHSVDATFEDQGPSPGYRIEMSIFYVVYFVVFPFFFVNIFVALIIITFQEQGDKVLSECSLEKNERACIDFAINAKPLTRYMPQNQQSFQYRLWKFVVSPPFEYSIMIMIALNTVVLMMKFH----------------GAPDFYEAMLKYLNIVFTVLFSLECILKIIAFGPLNYLKDAWNVFDFVTVLGSITDILVTEINTTERQLNFSFLRLFRAARLIKLLRQGYTIRILLWTFVQSFKALPYVCLLIAMLFFIYAIIGMQVFGNIDLNDDTAINRHNNFRTFLQALMLLFRSATGEAWHDIMLSCLSERTCDPS-SGTLGKECGSDFAYFYFVSFIFLCSFLMLNLFVAVIMDNFEYLTRDSSILGPHHLDEFIRVWAEYDPAACGRIKYLDMYEMLLHMSPPLGLGKKCPPRIAYKRLVKMNMPIADDNSVHFTSTLMALIRTALEIKLASGMVAQRLSDAELKKELSTVWPNLSQKTMDLLVTPHKP---NELTVGKVYAALMIFDYYKQNRAKRLQMQQQQLKEQAGPGSQNKVS 1918 HSP 2 Score: 719.153 bits (1855), Expect = 0.000e+0 Identity = 416/691 (60.20%), Postives = 508/691 (73.52%), Query Frame = 2 Query: 689 STSKSLFIFSEENVIRKYAKIIIEWGPFEYMVLLTILANCIVLSMERHLPKKDKTLLAGQLELTEKYFLGIFCVEALLKIVALGFCCHKEAYLRNVWNIMDFVVVVTGFLMMFLNIDNHSDSSTVDLRTLRAVRVLRPLKLVAGFPSLQVVLKSIIRAMAPLLQIGLLVLFAITIFAIIGLEFYSGAFHYTCFKANSDKLPLPIPTEKSLVPCSNSKNGSGLGAYTCPEDYQCKAYWEGPNYGITSFDNIGYAMLTVFQCITMEGWTDIMYHTNDAIGNRFNWLYFVPLIILGSFFMLNLVLGVLSGXXXXXXXXXXXXXXXLKLRRQQQTEKEFNGYMEWIQKAEEVLLNEATTTSEDKMRIIAARRRAEKQ----------------KYKLLGKNQSIPDFEYEDTELYSETKSMKGNIFIRSYAGIRRRRKERCTSFWRTEKHFRFSVRRLVKSQPFYWAVIILVFFNTVCVAIEHYEQGKWLTLFLNYAEYVFLCLFMMEMMIKMYGLSIRVYFQSSFNIFDCVVIAGSLFEIIYGIFVQDSSFGLSVLRALRLLRIFKVTRYWAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXGMQLFGGEFNFEEGKPPQNFDTFVKALLTVFQILTGEDWNTVMYNGIQSKGGVKERGTVFSIYFVLLVVFGNYTLLNVFLAIAVDNLAN 2713 + ++SLFIFSE+N+IRKYAK I EW PFEYM+L TI+ANCIVL +E+HLP DKT ++ +L+ TE YF+GIFC EA +KI+ALGF HK +YLRN WN+MDFVVV+TG L + DLRTLRAVRVLRPLKLV+G PSLQVVLKSI++AM PLLQIGLL+ FAI +FAIIGL+FY G FH TCF+ ++ + + PC G A+TC +C+ YW GPN+GIT+FDNI +A+LTVFQCITMEGW DI+Y+ NDA GN +NWLYF+PLII+GSFFMLNLVLGVLSGEFAKERERVEKR+ FLKLRRQQQ E+E GY+EWI KAEEV+L E +EDK + +R+ K KN I E ED + + +G+ F R+ ++ + E + F R EK FRF +RR+VK+Q FYW V+ +V NT+CVAI HY+Q +WLT L AE+VFL LF++EM +KMYGL R YF SSFN FD VI GS+FE+I+ +SFG+SVLRALRLLRIFKVT+YW SLRNLV+SLLNSM+SIISLLFLLFLFI++FALLGMQLFGG+FNFE+ P NFDTF A+LTVFQILTGEDWN VMY+GI+S+GGV RG S+YF++L +FGNYTLLNVFLAIAVDNLAN Sbjct: 65 TVNRSLFIFSEDNIIRKYAKKITEWPPFEYMILATIIANCIVLGLEQHLPALDKTPMSKRLDDTEPYFIGIFCFEAGIKIIALGFAFHKGSYLRNGWNVMDFVVVLTGILTIV--------GPDFDLRTLRAVRVLRPLKLVSGIPSLQVVLKSIMKAMVPLLQIGLLLFFAILMFAIIGLDFYMGKFHRTCFRTDTGE-------QVDEFPC-----GLESPAWTCENGTECREYWIGPNFGITNFDNILFAVLTVFQCITMEGWVDILYNANDASGNTWNWLYFIPLIIIGSFFMLNLVLGVLSGEFAKERERVEKRQEFLKLRRQQQIERELTGYLEWICKAEEVMLAEEDKNAEDKDDVAWYKRKCNNPGGFTRSLGADFGLPVLKRAKKSKNDLINAEEGEDHFTDISSVAPQGSPFTRT--SVKSSKIESLSYFRRKEKRFRFFIRRMVKAQSFYWTVLCIVGLNTLCVAIVHYDQPEWLTYALYLAEFVFLGLFLIEMSLKMYGLGPRTYFHSSFNCFDFGVIVGSIFEVIWAAVKPGASFGISVLRALRLLRIFKVTKYWNSLRNLVVSLLNSMKSIISLLFLLFLFIVVFALLGMQLFGGQFNFEDETPTTNFDTFPAAILTVFQILTGEDWNAVMYHGIESQGGV-HRGMFCSVYFIVLTLFGNYTLLNVFLAIAVDNLAN 732 HSP 3 Score: 118.242 bits (295), Expect = 1.159e-25 Identity = 93/343 (27.11%), Postives = 157/343 (45.77%), Query Frame = 2 Query: 539 CFASPYIPSNNKN--QRG-----ILTTVMSIDDGSKTTSMRSLAKRTINLSFPGM----QTSTS-----KSLFIFSEENVIRKYAKIIIEWGPFEYMVLLTILANCIVLSMERHLPKKDKTLLAGQLELTEKYFLGIFCVEALLKIVALGFCCHKEAYLRNVWNIMDFVVVVTGFLMMFLNIDNHSDSSTVDLRTLRAVRVLRPLKLVAGFPSLQVVLKSIIRAMAPLLQIGLLVLFAITIFAIIGLEFYSGAFHYTCFKANSDKLPLPIPTEKSLVPCSNSKNGSGLGAYTCPEDYQCKAY-WEGPNYGITSFDNIGYAMLTVFQCITMEGWTDIMYHTNDA 1516 C P N +N Q G I TV S + M S+ T+ ++ + Q+S S+FIF+ N +R+ I+ FE +L+ I + I L+ E P + L+ + F G+F E ++K+V LG H +Y R++WNI+DF+VV + + D ST+ ++LR +RVLRPLK + P L+ V ++ ++ +L I ++ + + IFA+I ++ + G F Y ++ K L K+ GL +D + W+ + +DN+ +A LT+F T EGW ++ H+ DA Sbjct: 1084 CLEKPEDSDNKRNIGQTGGMSTHIPVTVTSPPGETTLIPMNSIDSETVPMTEKNLEDLNQSSIRPILPFSSMFIFNPTNPVRRLCHYIVSLRYFEMCILVVIAMSSIALAAED--PVQANAPRNNVLKYLDYVFTGVFTFEMVIKMVDLGLILHPGSYFRDLWNILDFIVVSGALVAFAFSGTKGKDISTI--KSLRVLRVLRPLKTIKRLPKLKAVFDCVVNSLKNVLNILIVYILFMFIFAVIAVQLFKGKFFYCTDES------------KGL-----EKDCRGLFLDYDKDDVTAQPREWKKYEF---HYDNVLWAFLTLFTVSTGEGWPTVLKHSVDA 1402 HSP 4 Score: 115.931 bits (289), Expect = 6.027e-25 Identity = 80/293 (27.30%), Postives = 142/293 (48.46%), Query Frame = 2 Query: 3029 DPVPNKIEPETIQRKPVLPYSAMFIFSPLNSLRRFCHFVVNLRYFDLFIMIVICASSIALAAED--PVKEKSLKNNILEFFDYAFTGVFTVEMILKIIDLGIILHPGSYCRDLWNILDATVVICALVAFIMGQKPSPTGNKLRGSSAKNLNTIKSLRVLRVLRPLKTINRVPKLKAVFDCVVSSLKNVFNILIVYILFQFIFAVIAVQLFQGKF----FYCNDASKSSRETCRGYFFDYAGRSTPETKKRLWQHHDF---HFDNILYAMLTLFTVTTGEGWPTVLKNSMESTN 3880 +P+P K T+ R ++FIFS N +R++ + F+ I+ I A+ I L E P +K+ + L+ + F G+F E +KII LG H GSY R+ WN++D VV+ ++ + P + +++LR +RVLRPLK ++ +P L+ V ++ ++ + I ++ +FA+I + + GKF F + + C + + E ++ W +F +FDNIL+A+LT+F T EGW +L N+ +++ Sbjct: 55 NPIPVKQNCLTVNR-------SLFIFSEDNIIRKYAKKITEWPPFEYMILATIIANCIVLGLEQHLPALDKTPMSKRLDDTEPYFIGIFCFEAGIKIIALGFAFHKGSYLRNGWNVMDFVVVLTGILTIV-----GPDFD------------LRTLRAVRVLRPLKLVSGIPSLQVVLKSIMKAMVPLLQIGLLLFFAILMFAIIGLDFYMGKFHRTCFRTDTGEQVDEFPCGLESPAWTCENGTECRE-YWIGPNFGITNFDNILFAVLTVFQCITMEGWVDILYNANDASG 322 HSP 5 Score: 90.5077 bits (223), Expect = 3.210e-17 Identity = 72/258 (27.91%), Postives = 142/258 (55.04%), Query Frame = 2 Query: 1964 RTEKHFRFSVRRLVKSQPFYWAVIILVFFNTVCVAIEHYEQGKWLTLFLNYAEYVFLCLFMMEMMIKMYGLSIRVYFQSSFNIFDCVVIAGSLFEI-IYGIFVQDSSFGLSVLRALRLLRIFKVTRYWAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXGMQLFGG-EFNFEEG-KPPQNFDTFVKALLTVFQILTGEDWNTVMYNGIQ------SKGGV-KERGTVFS-IYFVLLVVFGNYTLLNVFLAIAVDN 2704 + ++ F++ + + V S PF ++++I++ NTV + ++ + + L Y VF LF +E ++K+ Y + ++N+FD V + GS+ +I + I + S LR R R+ K+ R ++R L+ + + S +++ + L+ + I+A++GMQ+FG + N + NF TF++AL+ +F+ TGE W+ +M + + S G + KE G+ F+ YFV + ++ +LN+F+A+ +DN Sbjct: 1480 QNQQSFQYRLWKFVVSPPFEYSIMIMIALNTVVLMMKFHGAPDFYEAMLKYLNIVFTVLFSLECILKIIAFGPLNYLKDAWNVFDFVTVLGSITDILVTEINTTERQLNFSFLRLFRAARLIKLLRQGYTIRILLWTFVQSFKALPYVCLLIAMLFFIYAIIGMQVFGNIDLNDDTAINRHNNFRTFLQALMLLFRSATGEAWHDIMLSCLSERTCDPSSGTLGKECGSDFAYFYFVSFIFLCSFLMLNLFVAVIMDN 1737 HSP 6 Score: 85.8853 bits (211), Expect = 7.077e-16 Identity = 74/292 (25.34%), Postives = 139/292 (47.60%), Query Frame = 2 Query: 4097 YMPKDKTTIKYRVWRLVVSTPFEYFIMVMIALNTLILMMKYYREEKKASSAATHDREQQAYLNYCNTLIFLNSAFTVMFSIECVLKIMAFGPKNYFRDPWNIFDFITVIGSITDVLVSELQDXXXXXXXXXXXXXXXXXXXXXXQGYTIRILLWTFIQSFKALPYVCLLIAMLFFIYSIIGMQVFGNIKLISEYQINRHN-----NFQTFTNGLLLLFRCATGESWQEIMLACDNNKPCEKDIENTNNFDCGSNFTYIYFVSFIFLCSFLMLNLFVAVIMDNF---DYLTRD 4948 Y + + ++ + R+V + F + ++ ++ LNTL + + +Y +Q +L Y L F +F IE LK+ GP+ YF +N FDF ++GSI +V+ + ++ + + LR R R+ K+ + ++R L+ + + S K++ + L+ + +++++GMQ+FG Q N + NF TF +L +F+ TGE W +M IE+ G F +YF+ ++ +LN+F+A+ +DN LT+D Sbjct: 481 YFRRKEKRFRFFIRRMVKAQSFYWTVLCIVGLNTLCVAIVHY--------------DQPEWLTYA--LYLAEFVFLGLFLIEMSLKMYGLGPRTYFHSSFNCFDFGVIVGSIFEVIWAAVKPGASFGISVLRALRLLRIFKVTKYWNSLRNLVVSLLNSMKSIISLLFLLFLFIVVFALLGMQLFGG-------QFNFEDETPTTNFDTFPAAILTVFQILTGEDWNAVMY---------HGIESQGGVHRGM-FCSVYFIVLTLFGNYTLLNVFLAIAVDNLANAQELTKD 739 HSP 7 Score: 74.7146 bits (182), Expect = 1.830e-12 Identity = 71/292 (24.32%), Postives = 117/292 (40.07%), Query Frame = 2 Query: 767 PFEYMVLLTILANCIVLSMERHLPKKDKTLLAGQLELTEKYFLGIFCVEALLKIVALGFCCHKEAYLRNVWNIMDFVVVVTGFLMMFLNIDNHSDSSTVDLRTLRAVRVLRPLKLVAGFPSLQVVLKSIIRAMAPLLQIGLLVLFAITIFAIIGLEFYSGAFHYTCFKANSDKLPLPIPTEKSLVPCSNSKNGSGLGAYTCPEDYQCKAYWEGPNYGITSFDNIGYAMLTVFQCITMEGWTDIMYHT-------------NDAIGNRFNWLYFVPLIILGSFFMLNLVLGVL 1603 PFEY +++ I N +VL M+ H L+ F +F +E +LKI+A G YL++ WN+ DFV V+ G + L + ++ ++ LR R R +KL+ +++++L + +++ L + LL+ I+AIIG++ + N D N N +F A++ +F+ T E W DIM G+ F + YFV I L SF MLNL + V+ Sbjct: 1497 PFEYSIMIMIALNTVVLMMKFH---GAPDFYEAMLKYLNIVFTVLFSLECILKIIAFG----PLNYLKDAWNVFDFVTVL-GSITDILVTEINTTERQLNFSFLRLFRAARLIKLLRQGYTIRILLWTFVQSFKALPYVCLLIAMLFFIYAIIGMQVFGN------IDLNDDT-------------AINRHN---------------------------NFRTFLQALMLLFRSATGEAWHDIMLSCLSERTCDPSSGTLGKECGSDFAYFYFVSFIFLCSFLMLNLFVAVI 1734 HSP 8 Score: 53.9138 bits (128), Expect = 3.758e-6 Identity = 50/203 (24.63%), Postives = 99/203 (48.77%), Query Frame = 2 Query: 3266 DYAFTGVFTVEMILKIIDLGIILHPGSYCRDLWNILDATVVICALVAFIMGQKPSPTGNKLRGSSAKNLNTIKSLRVLRVLRPLKTINRVPKLKAVFDCVVSSLKNVFNILIVYILFQFIFAVIAVQLFQGKFFYCNDASKSSRETCRGYFFDYAGRSTPETKKRLWQHHDFHFDNILYAMLTLFTVTTGEGWPTVLKNSMES 3874 ++ F G+F +EM LK+ LG P +Y +N D V++ ++ I ++ ++ ++ +++LR+LR+ + K N L+ + +++S+K++ ++L + LF +FA++ +QLF G+F + ++ TP T +FD A+LT+F + TGE W V+ + +ES Sbjct: 536 EFVFLGLFLIEMSLKMYGLG----PRTYFHSSFNCFDFGVIVGSIFEVIWA--------AVKPGASFGISVLRALRLLRIFKVTKYWN---SLRNLVVSLLNSMKSIISLLFLLFLFIVVFALLGMQLFGGQFNFEDE--------------------TPTT----------NFDTFPAAILTVFQILTGEDWNAVMYHGIES 693
BLAST of Voltage dependent L type calcium channel subunit vs. Ensembl Xenopus
Match: CACNA1C (calcium channel, voltage-dependent, L type, alpha 1C subunit [Source:NCBI gene;Acc:100488055]) HSP 1 Score: 1217.6 bits (3149), Expect = 0.000e+0 Identity = 758/1658 (45.72%), Postives = 1029/1658 (62.06%), Query Frame = 2 Query: 677 GMQTST--SKSLFIFSEENVIRKYAKIIIEWGPFEYMVLLTILANCIVLSMERHLPKKDKTLLAGQLELTEKYFLGIFCVEALLKIVALGFCCHKEAYLRNVWNIMDFVVVVTGFLMMFLNIDNHSDSSTV--------DLRTLRAVRVLRPLKLVAGFPSLQVVLKSIIRAMAPLLQIGLLVLFAITIFAIIGLEFYSGAFHYTCFKANSDKLPLPIPTEKSLVPCS-NSKNGSGLGAYTCPEDYQCKAYWEGPNYGITSFDNIGYAMLTVFQCITMEGWTDIMYHTNDAIGNRFNWLYFVPLIILGSFFMLNLVLGVLSGXXXXXXXXXXXXXXXLKLRRQQQTEKEFNGYMEWIQKAEEVLLNEATTTSEDKMRIIAARRRAEKQKYKLLGKNQSIPDFEYEDTELYSETKSMKGNIFIRSYAGIR---RRRKERCTSFWRTEKHF-RFSVRRLVKSQPFYWAVIILVFFNTVCVAIEHYEQGKWLTLFLNYAEYVFLCLFMMEMMIKMYGLSIRVYFQSSFNIFDCVVIAGSLFEIIYGIFVQDSSFGLSVLRALRLLRIFKVTRYWAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXGMQLFGGEFNFEEGKPPQN-FDTFVKALLTVFQILTGEDWNTVMYNGIQSKGGVKERGTVFSIYFVLLVVFGNYTLLNVFLAIAVDNLANXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSSDNFIGRLPL--------SIDPPMVQVCPPSPQTANSLIS-KNFSFDHNQVEVNDKGCLLNTNKPNGKLGMLGHDNTNFNSLESDPVPNKIEPETIQRK--PVLPYSAMFIFSPLNSLRRFCHFVVNLRYFDLFIMIVICASSIALAAEDPVKEKSLKNNILEFFDYAFTGVFTVEMILKIIDLGIILHPGSYCRDLWNILDATVVICALVAFIMGQKPSPTGNKLRGSSAKNLNTIKSLRVLRVLRPLKTINRVPKLKAVFDCVVSSLKNVFNILIVYILFQFIFAVIAVQLFQGKFFYCNDASKSSRETCRGYFFDY--AGRSTPETKKRLWQHHDFHFDNILYAMLTLFTVTTGEGWPTVLKNSMESTNIDNGPIADYRQEMAXXXXXXXXXXXXXXXXXXXALIIITFQEQGENELIDLDLDKNQKQCIDFAINEKPLCRYMPKDKTTIKYRVWRLVVSTPFEYFIMVMIALNTLILMMKYYREEKKASSAATHDREQQAYLNYCNTLIFLNSAFTVMFSIECVLKIMAFGPKNYFRDPWNIFDFITVIGSITDVLVSE---------LQDXXXXXXXXXXXXXXXXXXXXXXQGYTIRILLWTFIQSFKALPYVCLLIAMLFFIYSIIGMQVFGNIKLISEYQINRHNNFQTFTNGLLLLFRCATGESWQEIMLACDNNKPCEKDIENTNNFDCGSNFTYIYFVSFIFLCSFLMLNLFVAVIMDNFDYLTRDSSILGPHHLDEYIRVWAEYDPGAIGRIHHSEMYEMLRNMEPPVGFGKKCPYRLAYRKLIRMNMPVDENGTVNFTTTLFALIRESLNIKMSTAEYMDIKDMELRQTICKMWPVQAKKKLNLIVPPDSELVFHKMTVGKIYAGYLIVENWRAYKNSQEQG----PRSSPAVSIKSVTK------PVVKEEKSANLLAK 5506 G T+T ++L + +N IR+ I+EW PFE ++LLTI ANC+ L++ P+ D LE E FL IF VEA LK++A G H AYLRN WN++DF++VV G L +D + D++ LRA RVLRPL+LV+G PSLQVVL SII+AM PLL I LLVLF I I+AIIGLE + G H TC+ ++ P + TE+ PC+ S NG CP C++ W GP +GIT+FDN +AMLTVFQCITMEGWTD++Y DA+G +YFV L+I GSFF+LNLVLGVLSGEF+KERE+ + R F KLR +QQ E++ GY++WI +AE++ +++ +N S+P E E T ++ G+R R K + + +WR F R R VKS FYW VI LVF NT+ +A EHY Q WLT + A V L LF EM++KMY L ++ YF S FN FDC ++ G + E I S G+SVLR +RLLRIFK+TRYW SL NLV SLLNS+RSI SLL LLFLFI+IF+LLGMQLFGG+FNF+E ++ FD F +ALLTVFQILTGEDWN+VMY+GI + GG G + IYF++L + GNY LLNVFLAIAVDNLA+A+ LT+A++E+ E +R A E+K + +G+ P+ I+ + SP N+ IS + FS + N+ + T P+ + P + I+ K P+ SA F+F N R CH +VN F I+ I SSI+LAAEDPV+ S +N +L +FD FT +FTVE++LK+ G LH GS+CR+ +NILD VV +L++F G + +N +K LRVLRVLRPL+ INR LK V CV +++ + NI+IV L QF+FA I VQLF+GK + C D+SK + C+G + Y S P R W++ F FDN+L AM+ LFTV+T EGWP +L +++S D GPI ++R E++IF+I++ I+ FF +NIFV +I+TFQEQGE E + +LDKNQ+QC+++A+ +PL RY+PK++ +Y+VW +V ST FEY + V+I LNT+ L M++Y + ++ + LN FT +F++E +LK++AF PK YF DPWN+FDF+ VIGS+ DV++SE ++++S +S+ F RLFR RL+KLL +G IR LLWTFI+SF+ALPYV LLI MLFFIY++IGMQVFG I L +INR+NNFQTF +LLLFRCATGE+WQEIMLAC +KPC + E T+ CGS+F YF+SF LC+FL++NLFVAVIMDNFDYLTRD SILGPHHLDE+ R+WAEYDP A GRI H ++ +LR ++PP+GFGK CP+R+A ++L+ MNMP++ +GTV F TLFAL+R SL IK T ++ + ELR I K+W + K L+ +VPP + ++TVGK YA +LI E +R +K +EQG P A+S+++ + P ++ S +L A+ Sbjct: 100 GTTTATRPPRALLCLTLKNPIRRACISIVEWKPFEIIILLTIFANCVALAVYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIAYGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGGSAIGGKGAGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYYL-TNGYP-DVLTEEEPSPCALESNNGR-----HCPNGTLCRSGWVGPKHGITNFDNFAFAMLTVFQCITMEGWTDVLYWMQDAMGYELPCVYFVSLVIFGSFFVLNLVLGVLSGEFSKEREKAKARGDFQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEDIDEEK-----------------PRNMSMPTSETESVN----TDNVGSGDVEEESCGVRLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLTIASEHYNQPDWLTEVQDTANKVLLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFIVCGGILETILVETRIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDEMLTRRSTFDNFPQALLTVFQILTGEDWNSVMYDGIMAYGGPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLARTASPEKKQENESLGKSPVPAVEENKEKIELKAITADGESP--PNTKISVEEFSTNENEEK---------TPYPSSNETPGEEEEEEPEMPVGPR-PRPLSELHIKEKAAPMPEASAFFVFRSDNRFRVHCHRIVNNNIFTNLILFFILLSSISLAAEDPVRHNSFRNQVLFYFDIVFTAIFTVEIVLKMTAYGAFLHKGSFCRNYFNILDLLVVSVSLISF--------------GIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYSCTDSSKITEAECKGKYITYKDGDVSQPMIVDRSWENSKFDFDNVLSAMMALFTVSTFEGWPELLYRAIDSHTEDVGPIYNHRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLRRYIPKNQ--YQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQS----------------CSFKEAMNILNMLFTGLFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSVVDVILSETNVSISGQNVEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQEIMLACLPSKPCAPESE-TSEEKCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVAMNMPLNSDGTVMFNATLFALVRTSLCIK--TDGNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGD---DEVTVGKFYATFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAE 1679
BLAST of Voltage dependent L type calcium channel subunit vs. Ensembl Xenopus
Match: CACNA1C (calcium channel, voltage-dependent, L type, alpha 1C subunit [Source:NCBI gene;Acc:100488055]) HSP 1 Score: 1209.13 bits (3127), Expect = 0.000e+0 Identity = 754/1659 (45.45%), Postives = 1028/1659 (61.97%), Query Frame = 2 Query: 677 GMQTSTS--KSLFIFSEENVIRKYAKIIIEWGPFEYMVLLTILANCIVLSMERHLPKKDKTLLAGQLELTEKYFLGIFCVEALLKIVALGFCCHKEAYLRNVWNIMDFVVVVTGFLMMFLNIDNHSDSSTV--------DLRTLRAVRVLRPLKLVAGFPSLQVVLKSIIRAMAPLLQIGLLVLFAITIFAIIGLEFYSGAFHYTCFKANSDKLPLPIPTEKSLVPCS-NSKNGSGLGAYTCPEDYQCKAYWEGPNYGITSFDNIGYAMLTVFQCITMEGWTDIMYHTNDAIGNRFNWLYFVPLIILGSFFMLNLVLGVLSGXXXXXXXXXXXXXXXLKLRRQQQTEKEFNGYMEWIQKAEEVLLNEATTTSEDKMRIIAARRRAEKQKYKLLGKNQSIPDFEYEDTELYSETKSMKGNIFIRSYAGIR---RRRKERCTSFWRTEKHF-RFSVRRLVKSQPFYWAVIILVFFNTVCVAIEHYEQGKWLTLFLNYAEYVFLCLFMMEMMIKMYGLSIRVYFQSSFNIFDCVVIAGSLFEIIYGIFVQDSSFGLSVLRALRLLRIFKVTRYWAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXGMQLFGGEFNFEEGKPPQN-FDTFVKALLTVFQILTGEDWNTVMYNGIQSKGGVKERGTVFSIYFVLLVVFGNYTLLNVFLAIAVDNLANXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSSDNFIGRLPL--------SIDPPMVQVCPPSPQTANSLIS-KNFSFDHNQVEVNDKGCLLNTNKPNGKLGMLGHDNTNFNSLESDPVPNKIEPETIQRK--PVLPYSAMFIFSPLNSLRRFCHFVVNLRYFDLFIMIVICASSIALAAEDPVKEKSLKNNILEFFDYAFTGVFTVEMILKIIDLGIILHPGSYCRDLWNILDATVVICALVAFIMGQKPSPTGNKLRGSSAKNLNTIKSLRVLRVLRPLKTINRVPKLKAVFDCVVSSLKNVFNILIVYILFQFIFAVIAVQLFQGKFFYCNDASKSSRETCRGYFFDY--AGRSTPETKKRLWQHHDFHFDNILYAMLTLFTVTTGEGWPTVLKNSMESTNIDNGPIADYRQEMAXXXXXXXXXXXXXXXXXXXALIIITFQEQGENELIDLDLDKNQKQCIDFAINEKPLCRYMPKDKTTIKYRVWRLVVSTPFEYFIMVMIALNTLILMMKYYREEKKASSAATHDREQQAYLNYCNTLIFLNSAFTVMFSIECVLKIMAFGPKNYFRDPWNIFDFITVIGSITDVLVSEL----------QDXXXXXXXXXXXXXXXXXXXXXXQGYTIRILLWTFIQSFKALPYVCLLIAMLFFIYSIIGMQVFGNIKLISEYQINRHNNFQTFTNGLLLLFRCATGESWQEIMLACDNNKPCEKDIENTNNFDCGSNFTYIYFVSFIFLCSFLMLNLFVAVIMDNFDYLTRDSSILGPHHLDEYIRVWAEYDPGAIGRIHHSEMYEMLRNMEPPVGFGKKCPYRLAYRKLIRMNMPVDENGTVNFTTTLFALIRESLNIKMSTAEYMDIKDMELRQTICKMWPVQAKKKLNLIVPPDSELVFHKMTVGKIYAGYLIVENWRAYKNSQEQG----PRSSPAVSIKSVTK------PVVKEEKSANLLAK 5506 G T+T ++L + +N IR+ I+EW PFE ++LLTI ANC+ L++ P+ D LE E FL IF VEA LK++A G H AYLRN WN++DF++VV G L +D + D++ LRA RVLRPL+LV+G PSLQVVL SII+AM PLL I LLVLF I I+AIIGLE + G H TC+ ++ P + TE+ PC+ S NG CP C++ W GP +GIT+FDN +AMLTVFQCITMEGWTD++Y DA+G +YFV L+I GSFF+LNLVLGVLSGEF+KERE+ + R F KLR +QQ E++ GY++WI +AE++ R + + ++ + + +TE + G++ S G+R R K + + +WR F R R VKS FYW VI LVF NT+ +A EHY Q WLT + A V L LF EM++KMY L ++ YF S FN FDC ++ G + E I S G+SVLR +RLLRIFK+TRYW SL NLV SLLNS+RSI SLL LLFLFI+IF+LLGMQLFGG+FNF+E ++ FD F +ALLTVFQILTGEDWN+VMY+GI + GG G + IYF++L + GNY LLNVFLAIAVDNLA+A+ LT+A++E+ E +R A E+K + +G+ P+ I+ + SP N+ IS + FS + N+ + T P+ + P + I+ K P+ SA F+F N R CH +VN F I+ I SSI+LAAEDPV+ S +N +L +FD FT +FTVE++LK+ G LH GS+CR+ +NILD VV +L++F G + +N +K LRVLRVLRPL+ INR LK V CV +++ + NI+IV L QF+FA I VQLF+GK + C D+SK + C+G + Y S P R W++ F FDN+L AM+ LFTV+T EGWP +L +++S D GPI ++R E++IF+I++ I+ FF +NIFV +I+TFQEQGE E + +LDKNQ+QC+++A+ +PL RY+PK++ +Y+VW +V ST FEY + V+I LNT+ L M++Y + ++ + LN FT +F++E +LK++AF PK+YF D WN FD + V+GSI D+ ++EL +++S +S+ F RLFR RL+KLL +G IR LLWTFI+SF+ALPYV LLI MLFFIY++IGMQVFG I L +INR+NNFQTF +LLLFRCATGE+WQEIMLAC +KPC + E T+ CGS+F YF+SF LC+FL++NLFVAVIMDNFDYLTRD SILGPHHLDE+ R+WAEYDP A GRI H ++ +LR ++PP+GFGK CP+R+A ++L+ MNMP++ +GTV F TLFAL+R SL IK T ++ + ELR I K+W + K L+ +VPP + ++TVGK YA +LI E +R +K +EQG P A+S+++ + P ++ S +L A+ Sbjct: 99 GTTTATRPPRALLCLTLKNPIRRACISIVEWKPFEIIILLTIFANCVALAVYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIAYGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGGSAIGGKGAGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYYL-TNGYP-DVLTEEEPSPCALESNNGR-----HCPNGTLCRSGWVGPKHGITNFDNFAFAMLTVFQCITMEGWTDVLYWMQDAMGYELPCVYFVSLVIFGSFFVLNLVLGVLSGEFSKEREKAKARGDFQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEDI-----DEEKPRNSMSCAHMIIHASSASMSMPTSETESVNTDNVGSGDVEEES-CGVRLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLTIASEHYNQPDWLTEVQDTANKVLLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFIVCGGILETILVETRIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDEMLTRRSTFDNFPQALLTVFQILTGEDWNSVMYDGIMAYGGPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLARTASPEKKQENESLGKSPVPAVEENKEKIELKAITADGESP--PNTKISVEEFSTNENEEK---------TPYPSSNETPGEEEEEEPEMPVGPR-PRPLSELHIKEKAAPMPEASAFFVFRSDNRFRVHCHRIVNNNIFTNLILFFILLSSISLAAEDPVRHNSFRNQVLFYFDIVFTAIFTVEIVLKMTAYGAFLHKGSFCRNYFNILDLLVVSVSLISF--------------GIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYSCTDSSKITEAECKGKYITYKDGDVSQPMIVDRSWENSKFDFDNVLSAMMALFTVSTFEGWPELLYRAIDSHTEDVGPIYNHRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLRRYIPKNQ--YQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQS----------------CSFKEAMNILNMLFTGLFTVEMILKLIAFKPKHYFCDAWNTFDALIVVGSIVDIAITELNVSNPRLSNVEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQEIMLACLPSKPCAPESE-TSEEKCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVAMNMPLNSDGTVMFNATLFALVRTSLCIK--TDGNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGD---DEVTVGKFYATFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAE 1694
BLAST of Voltage dependent L type calcium channel subunit vs. Ensembl Xenopus
Match: CACNA1C (calcium channel, voltage-dependent, L type, alpha 1C subunit [Source:NCBI gene;Acc:100488055]) HSP 1 Score: 1204.12 bits (3114), Expect = 0.000e+0 Identity = 757/1687 (44.87%), Postives = 1028/1687 (60.94%), Query Frame = 2 Query: 677 GMQTST--SKSLFIFSEENVIRKYAKIIIEWGPFEYMVLLTILANCIVLSMERHLPKKDKTLLAGQLELTEKYFLGIFCVEALLKIVALGFCCHKEAYLRNVWNIMDFVVVVTGFLMMFLNIDNHSDSSTV--------DLRTLRAVRVLRPLKLVAGFPSLQVVLKSIIRAMAPLLQIGLLVLFAITIFAIIGLEFYSGAFHYTCFKANSDKLPLPIPTEKSLVPCS-NSKNGSGLGAYTCPEDYQCKAYWEGPNYGITSFDNIGYAMLTVFQCITMEGWTDIMYHTNDAIGNRFNWLYFVPLIILGSFFMLNLVLGVLSGXXXXXXXXXXXXXXXLKLRRQQQTEKEFNGYMEWIQKAEEVLLNEATTTSEDKMRIIAARRRAEKQKYKLLGKNQSIPDFEYEDTELYSETKSMKGNIFIRSYAGIR---RRRKERCTSFWRTEKHF-RFSVRRLVKSQPFYWAVIILVFFNTVCVAIEHYEQGKWLTLFLNYAEYVFLCLFMMEMMIKMYGLSIRVYFQSSFNIFDCVVIAGSLFEIIYGIFVQDSSFGLSVLRALRLLRIFKVTRYWAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXGMQLFGGEFNFEEGKPPQN-FDTFVKALLTVFQILTGEDWNTVMYNGIQSKGGVKERGTVFSIYFVLLVVFGNYTLLNVFLAIAVDNLANXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSSDNFIGRLPL--------SIDPPMVQVCPPSPQTANSLIS-KNFSFDHNQVEVNDKGCLLNTNKPNGKLGMLGHDNTNFNSLESDPVPNKIEPETIQRK--PVLPYSAMFIFSPLNSLRRFCHFVVNLRYFDLFIMIVICASSIALAAEDPVKEKSLKNNILEFFDYAFTGVFTVEMILKIIDLGIILHPGSYCRDLWNILDATVVICALVAFIMGQKPSPTGNKLRGSSAKNLNTIKSLRVLRVLRPLKTINRVPKLKAVFDCVVSSLKNVFNILIVYILFQFIFAVIAVQLFQGKFFYCNDASKSSRETCRGYFFDY--AGRSTPETKKRLWQHHDFHFDNILYAMLTLFTVTTGEGWPTVLKNSMESTNIDNGPIADYRQEMAXXXXXXXXXXXXXXXXXXXALIIITFQEQGENELIDLDLDKNQKQCIDFAINEKPLCRYMPKDKTTIKYRVWRLVVSTPFEYFIMVMIALNTLILMMKYYREEKKASSAATHDREQQAYLNYCNTLIFLNSAFTVMFSIECVLKIMAFGPKNYFRDPWNIFDFITVIGSITDVLV--------------------------------------SELQDXXXXXXXXXXXXXXXXXXXXXXQGYTIRILLWTFIQSFKALPYVCLLIAMLFFIYSIIGMQVFGNIKLISEYQINRHNNFQTFTNGLLLLFRCATGESWQEIMLACDNNKPCEKDIENTNNFDCGSNFTYIYFVSFIFLCSFLMLNLFVAVIMDNFDYLTRDSSILGPHHLDEYIRVWAEYDPGAIGRIHHSEMYEMLRNMEPPVGFGKKCPYRLAYRKLIRMNMPVDENGTVNFTTTLFALIRESLNIKMSTAEYMDIKDMELRQTICKMWPVQAKKKLNLIVPPDSELVFHKMTVGKIYAGYLIVENWRAYKNSQEQG----PRSSPAVSIKSVTK------PVVKEEKSANLLAK 5506 G T+T ++L + +N IR+ I+EW PFE ++LLTI ANC+ L++ P+ D LE E FL IF VEA LK++A G H AYLRN WN++DF++VV G L +D + D++ LRA RVLRPL+LV+G PSLQVVL SII+AM PLL I LLVLF I I+AIIGLE + G H TC+ ++ P + TE+ PC+ S NG CP C++ W GP +GIT+FDN +AMLTVFQCITMEGWTD++Y DA+G +YFV L+I GSFF+LNLVLGVLSGEF+KERE+ + R F KLR +QQ E++ GY++WI +AE++ +++ +N S+P E E T ++ G+R R K + + +WR F R R VKS FYW VI LVF NT+ +A EHY Q WLT + A V L LF EM++KMY L ++ YF S FN FDC ++ G + E I S G+SVLR +RLLRIFK+TRYW SL NLV SLLNS+RSI SLL LLFLFI+IF+LLGMQLFGG+FNF+E ++ FD F +ALLTVFQILTGEDWN+VMY+GI + GG G + IYF++L + GNY LLNVFLAIAVDNLA+A+ LT+A++E+ E +R A E+K + +G+ P+ I+ + SP N+ IS + FS + N+ + T P+ + P + I+ K P+ SA F+F N R CH +VN F I+ I SSI+LAAEDPV+ S +N +L +FD FT +FTVE++LK+ G LH GS+CR+ +NILD VV +L++F G + +N +K LRVLRVLRPL+ INR LK V CV +++ + NI+IV L QF+FA I VQLF+GK + C D+SK + C+G + Y S P R W++ F FDN+L AM+ LFTV+T EGWP +L +++S D GPI ++R E++IF+I++ I+ FF +NIFV +I+TFQEQGE E + +LDKNQ+QC+++A+ +PL RY+PK++ +Y+VW +V ST FEY + V+I LNT+ L M++Y + ++ + LN FT +F++E +LK++AF PK YF DPWN+FDF+ VIGS+ DV++ S ++++S +S+ F RLFR RL+KLL +G IR LLWTFI+SF+ALPYV LLI MLFFIY++IGMQVFG I L +INR+NNFQTF +LLLFRCATGE+WQEIMLAC +KPC + E T+ CGS+F YF+SF LC+FL++NLFVAVIMDNFDYLTRD SILGPHHLDE+ R+WAEYDP A GRI H ++ +LR ++PP+GFGK CP+R+A ++L+ MNMP++ +GTV F TLFAL+R SL IK T ++ + ELR I K+W + K L+ +VPP + ++TVGK YA +LI E +R +K +EQG P A+S+++ + P ++ S +L A+ Sbjct: 99 GTTTATRPPRALLCLTLKNPIRRACISIVEWKPFEIIILLTIFANCVALAVYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIAYGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGGSAIGGKGAGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYYL-TNGYP-DVLTEEEPSPCALESNNGR-----HCPNGTLCRSGWVGPKHGITNFDNFAFAMLTVFQCITMEGWTDVLYWMQDAMGYELPCVYFVSLVIFGSFFVLNLVLGVLSGEFSKEREKAKARGDFQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEDIDEEK-----------------PRNMSMPTSETESVN----TDNVGSGDVEEESCGVRLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLTIASEHYNQPDWLTEVQDTANKVLLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFIVCGGILETILVETRIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDEMLTRRSTFDNFPQALLTVFQILTGEDWNSVMYDGIMAYGGPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLARTASPEKKQENESLGKSPVPAVEENKEKIELKAITADGESP--PNTKISVEEFSTNENEEK---------TPYPSSNETPGEEEEEEPEMPVGPR-PRPLSELHIKEKAAPMPEASAFFVFRSDNRFRVHCHRIVNNNIFTNLILFFILLSSISLAAEDPVRHNSFRNQVLFYFDIVFTAIFTVEIVLKMTAYGAFLHKGSFCRNYFNILDLLVVSVSLISF--------------GIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYSCTDSSKITEAECKGKYITYKDGDVSQPMIVDRSWENSKFDFDNVLSAMMALFTVSTFEGWPELLYRAIDSHTEDVGPIYNHRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLRRYIPKNQ--YQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQS----------------CSFKEAMNILNMLFTGLFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSVVDVILSETNHYFCDAWNTFDALIVVGSIVDIAITELNVSNPRLSNVEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQEIMLACLPSKPCAPESE-TSEEKCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVAMNMPLNSDGTVMFNATLFALVRTSLCIK--TDGNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGD---DEVTVGKFYATFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAE 1707
BLAST of Voltage dependent L type calcium channel subunit vs. Ensembl Xenopus
Match: CACNA1C (calcium channel, voltage-dependent, L type, alpha 1C subunit [Source:NCBI gene;Acc:100488055]) HSP 1 Score: 1203.73 bits (3113), Expect = 0.000e+0 Identity = 751/1671 (44.94%), Postives = 1023/1671 (61.22%), Query Frame = 2 Query: 677 GMQTST--SKSLFIFSEENVIRKYAKIIIEWGPFEYMVLLTILANCIVLSMERHLPKKDKTLLAGQLELTEKYFLGIFCVEALLKIVALGFCCHKEAYLRNVWNIMDFVVVVTGFLMMFLNIDNHSDSSTV--------DLRTLRAVRVLRPLKLVAGFPSLQVVLKSIIRAMAPLLQIGLLVLFAITIFAIIGLEFYSGAFHYTCFKANSDKLPLPIPTEKSLVPCS-NSKNGSGLGAYTCPEDYQCKAYWEGPNYGITSFDNIGYAMLTVFQCITMEGWTDIMYHTNDAIGNRFNWLYFVPLIILGSFFMLNLVLGVLSGXXXXXXXXXXXXXXXLKLRRQQQTEKEFNGYMEWIQKAEEVLLNEATTTSEDKMRIIAARRRAEKQKYKLLGKNQSIPDFEYEDTELYSETKSMKGNIFIRSYAGIR---RRRKERCTSFWRTEKHF-RFSVRRLVKSQPFYWAVIILVFFNTVCVAIEHYEQGKWLTLFLNYAEYVFLCLFMMEMMIKMYGLSIRVYFQSSFNIFDCVVIAGSLFEIIYGIFVQDSSFGLSVLRALRLLRIFKVTRYWAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXGMQLFGGEFNFEEGKPPQN-FDTFVKALLTVFQILTGEDWNTVMYNGIQSKGGVKERGTVFSIYFVLLVVFGNYTLLNVFLAIAVDNLANXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSSDNFIGRLPLSIDPPMVQVCPPSPQTANSLISKNFSFDHNQVEVNDKGCLLNTNKPNGKLGMLGHDNTNFNSLESDPVPNK-----------------IEPETI------QRKPVLPYSAMF-IFSPLNSLRRFCHFVVNLRYFDLFIMIVICASSIALAAEDPVKEKSLKNNILEFFDYAFTGVFTVEMILKIIDLGIILHPGSYCRDLWNILDATVVICALVAFIMGQKPSPTGNKLRGSSAKNLNTIKSLRVLRVLRPLKTINRVPKLKAVFDCVVSSLKNVFNILIVYILFQFIFAVIAVQLFQGKFFYCNDASKSSRETCRGYFFDY--AGRSTPETKKRLWQHHDFHFDNILYAMLTLFTVTTGEGWPTVLKNSMESTNIDNGPIADYRQEMAXXXXXXXXXXXXXXXXXXXALIIITFQEQGENELIDLDLDKNQKQCIDFAINEKPLCRYMPKDKTTIKYRVWRLVVSTPFEYFIMVMIALNTLILMMKYYREEKKASSAATHDREQQAYLNYCNTLIFLNSAFTVMFSIECVLKIMAFGPKNYFRDPWNIFDFITVIGSITDVLVSELQ---------DXXXXXXXXXXXXXXXXXXXXXXQGYTIRILLWTFIQSFKALPYVCLLIAMLFFIYSIIGMQVFGNIKLISEYQINRHNNFQTFTNGLLLLFRCATGESWQEIMLACDNNKPCEKDIENTNNFDCGSNFTYIYFVSFIFLCSFLMLNLFVAVIMDNFDYLTRDSSILGPHHLDEYIRVWAEYDPGAIGRIHHSEMYEMLRNMEPPVGFGKKCPYRLAYRKLIRMNMPVDENGTVNFTTTLFALIRESLNIKMSTAEYMDIKDMELRQTICKMWPVQAKKKLNLIVPPDSELVFHKMTVGKIYAGYLIVENWRAYKNSQEQG----PRSSPAVSIKSVTK------PVVKEEKSANLLAK 5506 G T+T ++L + +N IR+ I+EW PFE ++LLTI ANC+ L++ P+ D LE E FL IF VEA LK++A G H AYLRN WN++DF++VV G L +D + D++ LRA RVLRPL+LV+G PSLQVVL SII+AM PLL I LLVLF I I+AIIGLE + G H TC+ ++ P + TE+ PC+ S NG CP C++ W GP +GIT+FDN +AMLTVFQCITMEGWTD++Y DA+G +YFV L+I GSFF+LNLVLGVLSGEF+KERE+ + R F KLR +QQ E++ GY++WI +AE++ +++ +N S+P E E T ++ G+R R K + + +WR F R R VKS FYW VI LVF NT+ +A EHY Q WLT + A V L LF EM++KMY L ++ YF S FN FDC ++ G + E I S G+SVLR +RLLRIFK+TRYW SL NLV SLLNS+RSI SLL LLFLFI+IF+LLGMQLFGG+FNF+E ++ FD F +ALLTVFQILTGEDWN+VMY+GI + GG G + IYF++L + GNY LLNVFLAIAVDNLA+A+ LT+A++E+ E +R A E+K + +G+ P+ P V + N+ ++ K + P + +TN N E P P+ P + ++ +P ++ F +F N R CH +VN F I+ I SSI+LAAEDPV+ S +N +L +FD FT +FTVE++LK+ G LH GS+CR+ +NILD VV +L++F G + +N +K LRVLRVLRPL+ INR LK V CV +++ + NI+IV L QF+FA I VQLF+GK + C D+SK + C+G + Y S P R W++ F FDN+L AM+ LFTV+T EGWP +L +++S D GPI ++R E++IF+I++ I+ FF +NIFV +I+TFQEQGE E + +LDKNQ+QC+++A+ +PL RY+PK++ +Y+VW +V ST FEY + V+I LNT+ L M++Y + ++ + LN FT +F++E +LK++AF PK+YF D WN FD + V+GSI D+ ++EL ++S +S+ F RLFR RL+KLL +G IR LLWTFI+SF+ALPYV LLI MLFFIY++IGMQVFG I L +INR+NNFQTF +LLLFRCATGE+WQEIMLAC +KPC + E T+ CGS+F YF+SF LC+FL++NLFVAVIMDNFDYLTRD SILGPHHLDE+ R+WAEYDP A GRI H ++ +LR ++PP+GFGK CP+R+A ++L+ MNMP++ +GTV F TLFAL+R SL IK T ++ + ELR I K+W + K L+ +VPP + ++TVGK YA +LI E +R +K +EQG P A+S+++ + P ++ S +L A+ Sbjct: 134 GTTTATRPPRALLCLTLKNPIRRACISIVEWKPFEIIILLTIFANCVALAVYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIAYGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGGSAIGGKGAGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYYL-TNGYP-DVLTEEEPSPCALESNNGR-----HCPNGTLCRSGWVGPKHGITNFDNFAFAMLTVFQCITMEGWTDVLYWMQDAMGYELPCVYFVSLVIFGSFFVLNLVLGVLSGEFSKEREKAKARGDFQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEDIDEEK-----------------PRNMSMPTSETESV----NTDNVGSGDVEEESCGVRLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLTIASEHYNQPDWLTEVQDTANKVLLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFIVCGGILETILVETRIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDEMLTRRSTFDNFPQALLTVFQILTGEDWNSVMYDGIMAYGGPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLARTASPEKKQENESLGKSPV----PAV--------------------EENKEKIELKAITADGESPPNTKISVEEFSTNENE-EKTPYPSSNETPGEEEEEEPEMPVGPRPRPLSELHIKEKAAPMPEASAFFVFRSDNRFRVHCHRIVNNNIFTNLILFFILLSSISLAAEDPVRHNSFRNQVLFYFDIVFTAIFTVEIVLKMTAYGAFLHKGSFCRNYFNILDLLVVSVSLISF--------------GIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYSCTDSSKITEAECKGKYITYKDGDVSQPMIVDRSWENSKFDFDNVLSAMMALFTVSTFEGWPELLYRAIDSHTEDVGPIYNHRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLRRYIPKNQ--YQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQS----------------CSFKEAMNILNMLFTGLFTVEMILKLIAFKPKHYFCDAWNTFDALIVVGSIVDIAITELNVSNPRLSVTENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQEIMLACLPSKPCAPESE-TSEEKCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVAMNMPLNSDGTVMFNATLFALVRTSLCIK--TDGNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGD---DEVTVGKFYATFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAE 1713
BLAST of Voltage dependent L type calcium channel subunit vs. Ensembl Xenopus
Match: CACNA1C (calcium channel, voltage-dependent, L type, alpha 1C subunit [Source:NCBI gene;Acc:100488055]) HSP 1 Score: 1199.5 bits (3102), Expect = 0.000e+0 Identity = 755/1671 (45.18%), Postives = 1024/1671 (61.28%), Query Frame = 2 Query: 677 GMQTSTS--KSLFIFSEENVIRKYAKIIIEWGPFEYMVLLTILANCIVLSMERHLPKKDKTLLAGQLELTEKYFLGIFCVEALLKIVALGFCCHKEAYLRNVWNIMDFVVVVTGFLMMFLNIDNHSDSSTV--------DLRTLRAVRVLRPLKLVAGFPSLQVVLKSIIRAMAPLLQIGLLVLFAITIFAIIGLEFYSGAFHYTCFKANSDKLPLPIPTEKSLVPCS-NSKNGSGLGAYTCPEDYQCKAYWEGPNYGITSFDNIGYAMLTVFQCITMEGWTDIMYHTNDAIGNRFNWLYFVPLIILGSFFMLNLVLGVLSGXXXXXXXXXXXXXXXLKLRRQQQTEKEFNGYMEWIQKAEEVLLNEATTTSEDKMRIIAARRRAEKQKYKLLGKNQSIPDFEYEDTELYSETKSMKGNIFIRSYAGIR---RRRKERCTSFWRTEKHF-RFSVRRLVKSQPFYWAVIILVFFNTVCVAIEHYEQGKWLTLFLNYAEYVFLCLFMMEMMIKMYGLSIRVYFQSSFNIFDCVVIAGSLFEIIYGIFVQDSSFGLSVLRALRLLRIFKVTRYWAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXGMQLFGGEFNFEEGKPPQN-FDTFVKALLTVFQILTGEDWNTVMYNGIQSKGGVKERGTVFSIYFVLLVVFGNYTLLNVFLAIAVDNLANXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSSDNFIGRLPL--------SIDPPMVQVCPPSPQTANSLIS-KNFSFDHNQVEVNDKGCLLNTNKPNGKLGMLGHDNTNFNSLESDPVPNKIEPETIQRK--PVLPYSAMFIFSPLNSLRRFCHFVVNLRYFDLFIMIVICASSIALAAEDPVKEKSLKNNILEFFDYAFTGVFTVEMILKIIDLGIILHPGSYCRDLWNILDATVVICALVAFIMGQKPSPTGNKLRGSSAKNLNTIKSLRVLRVLRPLKTINRVPKLKAVFDCVVSSLKNVFNILIVYILFQFIFAVIAVQLFQGKFFYCNDASKSSRETCRGYFFDY--AGRSTPETKKRLWQHHDFHFDNILYAMLTLFTVTTGEGWPTVLKNSMESTNIDNGPIADYRQEMAXXXXXXXXXXXXXXXXXXXALIIITFQEQGENELIDLDLDKNQKQCIDFAINEKPLCRYMPKDKTTIKYRVWRLVVSTPFEYFIMVMIALNTLILMMKYYREEKKASSAATHDREQQAYLNYCNTLIFLNSAFTVMFSIECVLKIMAFGPKNYFRDPWNIFDFITVIGSITDVLVSEL----------QDXXXXXXXXXXXXXXXXXXXXXXQGYTIRILLWTFIQSFKALPYVCLLIAMLFFIYSIIGMQVFGNIKLISEYQINRHNNFQTFTNGLLLLFRCATGESWQEIMLACDNNKPCEKDIENTNNFDCGSNFTYIYFVSFIFLCSFLMLNLFVAVIMDNFDYLTRDSSILGPHHLDEYIRVWAEYDPGAIGRIHHSEMYEMLRNMEPPVGFGKKCPYRLAYRKLIRMNMPVDENGTVNFTTTLFALIRESLNIKMSTAEY------------MDIKDMELRQTICKMWPVQAKKKLNLIVPPDSELVFHKMTVGKIYAGYLIVENWRAYKNSQEQG----PRSSPAVSIKSVTK------PVVKEEKSANLLAK 5506 G T+T ++L + +N IR+ I+EW PFE ++LLTI ANC+ L++ P+ D LE E FL IF VEA LK++A G H AYLRN WN++DF++VV G L +D + D++ LRA RVLRPL+LV+G PSLQVVL SII+AM PLL I LLVLF I I+AIIGLE + G H TC+ ++ P + TE+ PC+ S NG CP C++ W GP +GIT+FDN +AMLTVFQCITMEGWTD++Y DA+G +YFV L+I GSFF+LNLVLGVLSGEF+KERE+ + R F KLR +QQ E++ GY++WI +AE++ +++ +N S+P E E T ++ G+R R K + + +WR F R R VKS FYW VI LVF NT+ +A EHY Q WLT + A V L LF EM++KMY L ++ YF S FN FDC ++ G + E I S G+SVLR +RLLRIFK+TRYW SL NLV SLLNS+RSI SLL LLFLFI+IF+LLGMQLFGG+FNF+E ++ FD F +ALLTVFQILTGEDWN+VMY+GI + GG G + IYF++L + GNY LLNVFLAIAVDNLA+A+ LT+A++E+ E +R A E+K + +G+ P+ I+ + SP N+ IS + FS + N+ + T P+ + P + I+ K P+ SA F+F N R CH +VN F I+ I SSI+LAAEDPV+ S +N IL DY FT +FT+E+ILK+ G LH GS+CR+ +NILD VV +L++F G + +N +K LRVLRVLRPL+ INR LK V CV +++ + NI+IV L QF+FA I VQLF+GK + C D+SK + C+G + Y S P R W++ F FDN+L AM+ LFTV+T EGWP +L +++S D GPI ++R E++IF+I++ I+ FF +NIFV +I+TFQEQGE E + +LDKNQ+QC+++A+ +PL RY+PK++ +Y+VW +V ST FEY + V+I LNT+ L M++Y + ++ + LN FT +F++E +LK++AF PK+YF D WN FD + V+GSI D+ ++EL +++S +S+ F RLFR RL+KLL +G IR LLWTFI+SF+ALPYV LLI MLFFIY++IGMQVFG I L +INR+NNFQTF +LLLFRCATGE+WQEIMLAC +KPC + E T+ CGS+F YF+SF LC+FL++NLFVAVIMDNFDYLTRD SILGPHHLDE+ R+WAEYDP A GRI H ++ +LR ++PP+GFGK CP+R+A ++L+ MNMP++ +GTV F TLFAL+R SL IK ++ + ELR I K+W + K L+ +VPP + ++TVGK YA +LI E +R +K +EQG P A+S+++ + P ++ S +L A+ Sbjct: 99 GTTTATRPPRALLCLTLKNPIRRACISIVEWKPFEIIILLTIFANCVALAVYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIAYGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGGSAIGGKGAGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYYL-TNGYP-DVLTEEEPSPCALESNNGR-----HCPNGTLCRSGWVGPKHGITNFDNFAFAMLTVFQCITMEGWTDVLYWMQDAMGYELPCVYFVSLVIFGSFFVLNLVLGVLSGEFSKEREKAKARGDFQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEDIDEEK-----------------PRNMSMPTSETESVN----TDNVGSGDVEEESCGVRLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLTIASEHYNQPDWLTEVQDTANKVLLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFIVCGGILETILVETRIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDEMLTRRSTFDNFPQALLTVFQILTGEDWNSVMYDGIMAYGGPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLARTASPEKKQENESLGKSPVPAVEENKEKIELKAITADGESP--PNTKISVEEFSTNENEEK---------TPYPSSNETPGEEEEEEPEMPVGPR-PRPLSELHIKEKAAPMPEASAFFVFRSDNRFRVHCHRIVNNNIFTNLILFFILLSSISLAAEDPVRHNSFRNQILGNADYVFTSIFTLEIILKMTAYGAFLHKGSFCRNYFNILDLLVVSVSLISF--------------GIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYSCTDSSKITEAECKGKYITYKDGDVSQPMIVDRSWENSKFDFDNVLSAMMALFTVSTFEGWPELLYRAIDSHTEDVGPIYNHRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLRRYIPKNQ--YQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQS----------------CSFKEAMNILNMLFTGLFTVEMILKLIAFKPKHYFCDAWNTFDALIVVGSIVDIAITELNVSNPRLSNVEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQEIMLACLPSKPCAPESE-TSEEKCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVAMNMPLNSDGTVMFNATLFALVRTSLCIKTDGNSLLLLFACQIFSWNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGD---DEVTVGKFYATFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAE 1693
BLAST of Voltage dependent L type calcium channel subunit vs. Ensembl Mouse
Match: Cacna1c (calcium channel, voltage-dependent, L type, alpha 1C subunit [Source:MGI Symbol;Acc:MGI:103013]) HSP 1 Score: 1245.72 bits (3222), Expect = 0.000e+0 Identity = 765/1650 (46.36%), Postives = 1037/1650 (62.85%), Query Frame = 2 Query: 686 TSTSKSLFIFSEENVIRKYAKIIIEWGPFEYMVLLTILANCIVLSMERHLPKKDKTLLAGQLELTEKYFLGIFCVEALLKIVALGFCCHKEAYLRNVWNIMDFVVVVTGFLMMFLNIDNHSDSSTV--------DLRTLRAVRVLRPLKLVAGFPSLQVVLKSIIRAMAPLLQIGLLVLFAITIFAIIGLEFYSGAFHYTCFKANSDKLPLPIPTEKSLVPCSNSKNGSGLGAYTCPEDYQCKAYWEGPNYGITSFDNIGYAMLTVFQCITMEGWTDIMYHTNDAIGNRFNWLYFVPLIILGSFFMLNLVLGVLSGXXXXXXXXXXXXXXXLKLRRQQQTEKEFNGYMEWIQKAEEV-LLNEATTTSEDKMRIIAARRRAEKQKYKLLG-------KNQSIPDFEYEDTELYSETKSMKGNIFIRSYAGIR---RRRKERCTSFWRTEKHF-RFSVRRLVKSQPFYWAVIILVFFNTVCVAIEHYEQGKWLTLFLNYAEYVFLCLFMMEMMIKMYGLSIRVYFQSSFNIFDCVVIAGSLFEIIYGIFVQDSSFGLSVLRALRLLRIFKVTRYWAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXGMQLFGGEFNFEEGKPPQN-FDTFVKALLTVFQILTGEDWNTVMYNGIQSKGGVKERGTVFSIYFVLLVVFGNYTLLNVFLAIAVDNLANXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSSDNFIGRLPLSIDPPMVQVCPPSPQTANSLISKNFSFDHNQVEVNDKGCLLNTNK-PNGKLGMLGHDNTNFNSLESDPVPNKIEPETIQRK--PVLPYSAMFIFSPLNSLRRFCHFVVNLRYFDLFIMIVICASSIALAAEDPVKEKSLKNNILEFFDYAFTGVFTVEMILKIIDLGIILHPGSYCRDLWNILDATVVICALVAFIMGQKPSPTGNKLRGSSAKNLNTIKSLRVLRVLRPLKTINRVPKLKAVFDCVVSSLKNVFNILIVYILFQFIFAVIAVQLFQGKFFYCNDASKSSRETCRGYFFDYAGRST--PETKKRLWQHHDFHFDNILYAMLTLFTVTTGEGWPTVLKNSMESTNIDNGPIADYRQEMAXXXXXXXXXXXXXXXXXXXALIIITFQEQGENELIDLDLDKNQKQCIDFAINEKPLCRYMPKDKTTIKYRVWRLVVSTPFEYFIMVMIALNTLILMMKYYREEKKASSAATHDREQQAYLNYCNTLIFLNSAFTVMFSIECVLKIMAFGPKNYFRDPWNIFDFITVIGSITDVLVSE---LQDXXXXXXXXXXXXXXXXXXXXXXQGYTIRILLWTFIQSFKALPYVCLLIAMLFFIYSIIGMQVFGNIKLISEYQINRHNNFQTFTNGLLLLFRCATGESWQEIMLACDNNKPCEKDIENTNNFD----CGSNFTYIYFVSFIFLCSFLMLNLFVAVIMDNFDYLTRDSSILGPHHLDEYIRVWAEYDPGAIGRIHHSEMYEMLRNMEPPVGFGKKCPYRLAYRKLIRMNMPVDENGTVNFTTTLFALIRESLNIKMSTAEYMDIKDMELRQTICKMWPVQAKKKLNLIVPPDSELVFHKMTVGKIYAGYLIVENWRAYKNSQEQG----PRSSPAVSIKSVTK------PVVKEEKSANLLAK 5506 T ++L + +N IR+ I+EW PFE ++LLTI ANC+ L++ P+ D LE E FL IF VEA LK++A G H AYLRN WN++DF++VV G L +D + D++ LRA RVLRPL+LV+G PSLQVVL SII+AM PLL I LLVLF I I+AIIGLE + G H TC+ N + + + +P E+ PC+ + G G C CK W+GP +GIT+FDN +AMLTVFQCITMEGWTD++Y NDA+G + W+YFV LII+GSFF+LNLVLGVLSGEF+KERE+ + R F KLR +QQ E++ GY++WI +AE++ NE EDK R A QK + S+P E E T+++ G G R R K + + +WR F R R VKS FYW VI LVF NT+ +A EHY Q WLT + A L LF EM++KMY L ++ YF S FN FDC ++ G + E I S G+SVLR +RLLRIFK+TRYW SL NLV SLLNS+RSI SLL LLFLFI+IF+LLGMQLFGG+FNF+E + ++ FD F ++LLTVFQILTGEDWN+VMY+GI + GG G + IYF++L + GNY LLNVFLAIAVDNLA+A+ LT+A++E+ E +R A E+K ++ P V+ S+ + S ++ ++D N +K P+ G ++ + P P + ++ K P+ SA FIFSP N R CH +VN F I+ I SSI+LAAEDPV+ S +N+IL +FD FT +FT+E+ LK+ G LH GS+CR+ +NILD VV +L++F G + +N +K LRVLRVLRPL+ INR LK V CV +++ + NI+IV L QF+FA I VQLF+GK + C+D+SK + C+G + Y P + R W++ F FDN+L AM+ LFTV+T EGWP +L S++S D GPI +YR E++IF+I++ I+ FF +NIFV +I+TFQEQGE E + +LDKNQ+QC+++A+ +PL RY+PK++ +Y+VW +V ST FEY + V+I LNT+ L M++Y Q+ L + + LN FT +F++E +LK++AF PK YF DPWN+FDF+ VIGSI DV++SE +++S +S+ F RLFR RL+KLL +G IR LLWTFI+SF+ALPYV LLI MLFFIY++IGMQVFG I L +INR+NNFQTF +LLLFRCATGE+WQ+IMLAC K C + E +N+ + CGS+F YF+SF LC+FL++NLFVAVIMDNFDYLTRD SILGPHHLDE+ R+WAEYDP A GRI H ++ +LR ++PP+GFGK CP+R+A ++L+ MNMP++ +GTV F TLFAL+R +L IK T ++ + ELR I K+W + K L+ +VPP + ++TVGK YA +LI E +R +K +EQG P A+S+++ + P ++ S +L A+ Sbjct: 98 TRPPRALLCLTLKNPIRRACISIVEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIAYGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCY--NQEGI-IDVPAEEDPSPCA-LETGHG---RQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCITMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGDFQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEDKPRNRGAPAGLHDQKKGKFAWFSHSTETHVSMPTSETESVN----TENVAGGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLTIASEHYNQPHWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFIVCGGILETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYGGPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLARTASPEKKQE---------VMEKPAVEESKEEKIELKSITADGESPPTTKINMDDLQPSENEDKSPHSNPDTAGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSPNNRFRLQCHRIVNDTIFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALKMTAYGAFLHKGSFCRNYFNILDLLVVSVSLISF--------------GIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGEVDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLRRYIPKNQH--QYKVWYVVNSTYFEYLMFVLILLNTICLAMQHY---------------GQSCL-FKIAMNILNMLFTGLFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVILSETNSAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRIK--TEGNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGD---DEVTVGKFYATFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAE 1690
BLAST of Voltage dependent L type calcium channel subunit vs. Ensembl Mouse
Match: Cacna1s (calcium channel, voltage-dependent, L type, alpha 1S subunit [Source:MGI Symbol;Acc:MGI:88294]) HSP 1 Score: 1242.64 bits (3214), Expect = 0.000e+0 Identity = 745/1614 (46.16%), Postives = 1017/1614 (63.01%), Query Frame = 2 Query: 641 SLAKRTINLSFPGMQTSTSKSLFIFSEENVIRKYAKIIIEWGPFEYMVLLTILANCIVLSMERHLPKKDKTLLAGQLELTEKYFLGIFCVEALLKIVALGFCCHKEAYLRNVWNIMDFVVVVTGFLMMFLNIDN---------HSDSSTVDLRTLRAVRVLRPLKLVAGFPSLQVVLKSIIRAMAPLLQIGLLVLFAITIFAIIGLEFYSGAFHYTCFKANSDKLPLPIPTEKSLVPCSNSKNGSGLGAYTCPEDYQCKAYWEGPNYGITSFDNIGYAMLTVFQCITMEGWTDIMYHTNDAIGNRFNWLYFVPLIILGSFFMLNLVLGVLSGXXXXXXXXXXXXXXXLKLRRQQQTEKEFNGYMEWIQKAEEVLLNEATTTSEDKMRIIAARRRAEKQKYKLLGKNQSIPDFEYEDTELYSETKSMKGNI-FIRSYAGIRRRRKERCTSFWRT-EKHFRFSVRRLVKSQPFYWAVIILVFFNTVCVAIEHYEQGKWLTLFLNYAEYVFLCLFMMEMMIKMYGLSIRVYFQSSFNIFDCVVIAGSLFEIIYGIFVQDSSFGLSVLRALRLLRIFKVTRYWAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXGMQLFGGEFNFEEGKPPQ-NFDTFVKALLTVFQILTGEDWNTVMYNGIQSKGGVKERGTVFSIYFVLLVVFGNYTLLNVFLAIAVDNLANXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSSDNFIGRLPLSIDPPMVQVCPPSPQTANSLISKNFSFDHNQVEVNDKGCLLNTNKPNGKLGMLGHDNTNFNSLESDPVPNKIEPETIQRK--PVLPYSAMFIFSPLNSLRRFCHFVVNLRYFDLFIMIVICASSIALAAEDPVKEKSLKNNILEFFDYAFTGVFTVEMILKIIDLGIILHPGSYCRDLWNILDATVVICALVAFIMGQKPSPTGNKLRGSSAKNLNTIKSLRVLRVLRPLKTINRVPKLKAVFDCVVSSLKNVFNILIVYILFQFIFAVIAVQLFQGKFFYCNDASKSSRETCRGYFFDYA-GRSTP-ETKKRLWQHHDFHFDNILYAMLTLFTVTTGEGWPTVLKNSMESTNIDNGPIADYRQEMAXXXXXXXXXXXXXXXXXXXALIIITFQEQGENELIDLDLDKNQKQCIDFAINEKPLCRYMPKDKTTIKYRVWRLVVSTPFEYFIMVMIALNTLILMMKYYREEKKASSAATHDREQQAYLNYCNTLIFLNSAFTVMFSIECVLKIMAFGPKNYFRDPWNIFDFITVIGSITDVLVSELQDXXXXXXXXXX---XXXXXXXXXXXXQGYTIRILLWTFIQSFKALPYVCLLIAMLFFIYSIIGMQVFGNIKLISEYQINRHNNFQTFTNGLLLLFRCATGESWQEIMLACDNNKPC--EKDIENTNNFDCGSNFTYIYFVSFIFLCSFLMLNLFVAVIMDNFDYLTRDSSILGPHHLDEYIRVWAEYDPGAIGRIHHSEMYEMLRNMEPPVGFGKKCPYRLAYRKLIRMNMPVDENGTVNFTTTLFALIRESLNIKMSTAEYMDIKDMELRQTICKMWPVQAKKKLNLIVPPDSELVFHKMTVGKIYAGYLIVENWRAYKNSQEQ 5419 L K+ P + ++LF + +N +RK I+EW PFE ++LLTI ANC+ L++ +P+ D L LE E +FL +F +EA +KI+A GF H++AYLR+ WN++DF++V G + L N S + +D++ LRA RVLRPL+LV+G PSLQVVL SI +AM PL I LLVLF + I+AIIGLE + G H TC+ +D + T ++ P ++ GSG +C+ W GPN+GIT FDN G++MLTV+QCI+MEGWTD++Y NDAIGN + W+YFV LI+LGSFF+LNLVLGVLSGEF KERE+ + R F KLR +QQ E++ GYM WI + E + + E K+ + D DTE E + + I FIR WR + FR+ LVKS+ FYW VI++V NT+ +A EH+ Q WLT + A V L LF +EM++KMYGL +R YF S FN FDC V+ + EI+ S G+SVLR +RLLR+FK+T+YW SL NLV SLLNS+RSI SLL LLFLFI+IFALLGMQLFGG ++FE+ + + NFD F +AL++VFQ+LTGEDWN+VMYNGI + GG G + IYF++L V GNY LLNVFLAIAVDNLA A+ LT+A++ KA E +R + L ++ + R ++ P TA I + F+ N EV D P G D + + P P + ++ K P+ S+ FIFSP N +R CH +VN +F FI++ I SS ALAAEDP++ S++N ILE+FDY FT VFTVE++LK+ G LH GS+CR+ +NILD VV +L++ G + ++ +K LRVLRVLRPL+ INR LK V CV +++ + NI++V L QF+FA I VQLF+GKF+ CND SK + E CRGY++ Y G T E + R W H+DFHFDN+L AM++LFTV+T EGWP +L +++S D GP+ + R EMAIF+I++ I+ FF +NIFV +I+TFQEQGE E + +LDKNQ+QC+ +A+ +PL Y+PK+ +Y+VW +V S+ FEY + +I LNT+ L M++Y + ++ +N+ + + LN AFT++F++E VLK++AF P+ YF DPWN+FDF+ VIGSI DV++SE+ D + LFR RL+KLL + +R LLWTFI+SF+ALPYV LLI MLFFIY++IGMQ+FG I ++ QINR+NNFQTF +LLLFRCATGE+WQEI+LAC K C E D CG+NF Y YF+SF LC+FL++NLFVAVIMDNFDYLTRD SILGPHHLDE+ +WAEYDP A GRI H ++ +LR ++PP+GFGK CP+R+A ++L+ MNMP++ +GTV F TLFAL+R +L IK T + + ELR I K+W + K L+ ++PP + ++TVGK YA +LI E++R + QE+ Sbjct: 10 GLRKKQPKKPVPEILPRPPRALFCLTLQNPLRKACISIVEWKPFETIILLTIFANCVALAVYLPMPEDDNNTLNLGLEKLEYFFLIVFSIEAAMKIIAYGFLFHQDAYLRSGWNVLDFIIVFLGVFTVILEQVNIIQTNTAPMSSKGAGLDVKALRAFRVLRPLRLVSGVPSLQVVLNSIFKAMLPLFHIALLVLFMVIIYAIIGLELFKGKMHKTCYFIGTDI----VATVENEKPSPCARTGSGRPCTI--NGSECRGGWPGPNHGITHFDNFGFSMLTVYQCISMEGWTDVLYWVNDAIGNEWPWIYFVTLILLGSFFILNLVLGVLSGEFTKEREKAKSRGTFQKLREKQQLEEDLRGYMSWITQGE---VMDVDDLREGKLSL----------------------DEGGSDTESLYEIEGLNKIIQFIRH---------------WRQWNRVFRWKCHDLVKSKVFYWLVILIVALNTLSIASEHHNQPLWLTHLQDVANRVLLTLFTIEMLMKMYGLGLRQYFMSIFNRFDCFVVCSGILEILLVESGAMSPLGISVLRCIRLLRLFKITKYWTSLSNLVASLLNSIRSIASLLLLLFLFIIIFALLGMQLFGGRYDFEDTEVRRSNFDNFPQALISVFQVLTGEDWNSVMYNGIMAYGGPTYPGVLVCIYFIILFVCGNYILLNVFLAIAVDNLAEAESLTSAQKAKAEERKRRKMSKGLPDKSEEE-----RATVTKKLEQKSKGEGIPTTAKLKIDE---FESNVNEVKD---------PYPSADFPGDDEEDEPEIPVSPRPRPLAELQLKEKAVPIPEASSFFIFSPTNKIRVLCHRIVNATWFTNFILLFILLSSAALAAEDPIRADSMRNQILEYFDYVFTAVFTVEIVLKMTTYGAFLHKGSFCRNYFNILDLLVVAVSLISM--------------GLESSAISVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVLVTTLLQFMFACIGVQLFKGKFYSCNDLSKMTEEECRGYYYIYKDGDPTQIELRPRQWIHNDFHFDNVLSAMMSLFTVSTFEGWPQLLYKAIDSNEEDTGPVYNNRVEMAIFFIIYIILIAFFMMNIFVGFVIVTFQEQGETEYKNCELDKNQRQCVQYALKARPLRCYIPKNP--YQYQVWYVVTSSYFEYLMFALIMLNTICLGMQHYNQSEQ--------------MNHISDI--LNVAFTIIFTLEMVLKLIAFKPRGYFGDPWNVFDFLIVIGSIIDVILSEIDDPDESARISSAFFRLFRVMRLVKLLNRAEGVRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQMFGKIAMVDGTQINRNNNFQTFPQAVLLLFRCATGEAWQEILLACSYGKLCDPESDYAPGEEHTCGTNFAYYYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKAIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKFCPHRVACKRLVGMNMPLNSDGTVTFNATLFALVRTALKIK--TEGNFEQANEELRAIIKKIWKRTSMKLLDQVIPPIGD---DEVTVGKFYATFLIQEHFRKFMKRQEE 1523
BLAST of Voltage dependent L type calcium channel subunit vs. Ensembl Mouse
Match: Cacna1c (calcium channel, voltage-dependent, L type, alpha 1C subunit [Source:MGI Symbol;Acc:MGI:103013]) HSP 1 Score: 1242.25 bits (3213), Expect = 0.000e+0 Identity = 764/1654 (46.19%), Postives = 1034/1654 (62.52%), Query Frame = 2 Query: 686 TSTSKSLFIFSEENVIRKYAKIIIEWGPFEYMVLLTILANCIVLSMERHLPKKDKTLLAGQLELTEKYFLGIFCVEALLKIVALGFCCHKEAYLRNVWNIMDFVVVVTGFLMMFLNIDNHSDSSTV--------DLRTLRAVRVLRPLKLVAGFPSLQVVLKSIIRAMAPLLQIGLLVLFAITIFAIIGLEFYSGAFHYTCFKANSDKLPLPIPTEKSLVPCSNSKNGSGLGAYTCPEDYQCKAYWEGPNYGITSFDNIGYAMLTVFQCITMEGWTDIMYHTNDAIGNRFNWLYFVPLIILGSFFMLNLVLGVLSGXXXXXXXXXXXXXXXLKLRRQQQTEKEFNGYMEWIQKAEEV-LLNEATTTSEDKMRIIAARRRAEKQKYKLLGKNQSIPDFEYEDTELYSETKSMKGNIFIRSYAGIR---RRRKERCTSFWRTEKHF-RFSVRRLVKSQPFYWAVIILVFFNTVCVAIEHYEQGKWLTLFLNYAEYVFLCLFMMEMMIKMYGLSIRVYFQSSFNIFDCVVIAGSLFEIIYGIFVQDSSFGLSVLRALRLLRIFKVTRYWAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXGMQLFGGEFNFEEGKPPQN-FDTFVKALLTVFQILTGEDWNTVMYNGIQSKGGVKERGTVFSIYFVLLVVFGNYTLLNVFLAIAVDNLANXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSSDNFIGRLPLSIDPPMVQVCPPSPQTANSLISKNFSFDHNQVEVNDKGCLLNTNK-PNGKLGMLGHDNTNFNSLESDPVPNKIEPETIQRK--PVLPYSAMFIFSPLNSLRRFCHFVVNLRYFDLFIMIVICASSIALAAEDPVKEKSLKNNILEFFDYAFTGVFTVEMILKIIDLGIILHPGSYCRDLWNILDATVVICALVAFIMGQKPSPTGNKLRGSSAKNLNTIKSLRVLRVLRPLKTINRVPKLKAVFDCVVSSLKNVFNILIVYILFQFIFAVIAVQLFQGKFFYCNDASKSSRETCRGYFFDYAGRST--PETKKRLWQHHDFHFDNILYAMLTLFTVTTGEGWPTVLKNSMESTNIDNGPIADYRQEMAXXXXXXXXXXXXXXXXXXXALIIITFQEQGENELIDLDLDKNQKQCIDFAINEKPLCRYMPKDKTTIKYRVWRLVVSTPFEYFIMVMIALNTLILMMKYYREEKKASSAATHDREQQAYLNYCNTLIFLNSAFTVMFSIECVLKIMAFGPKNYFRDPWNIFDFITVIGSITDVLVSE--------------LQDXXXXXXXXXXXXXXXXXXXXXXQGYTIRILLWTFIQSFKALPYVCLLIAMLFFIYSIIGMQVFGNIKLISEYQINRHNNFQTFTNGLLLLFRCATGESWQEIMLACDNNKPCEKDIENTNNFD----CGSNFTYIYFVSFIFLCSFLMLNLFVAVIMDNFDYLTRDSSILGPHHLDEYIRVWAEYDPGAIGRIHHSEMYEMLRNMEPPVGFGKKCPYRLAYRKLIRMNMPVDENGTVNFTTTLFALIRESLNIKMSTAEYMDIKDMELRQTICKMWPVQAKKKLNLIVPPDSELVFHKMTVGKIYAGYLIVENWRAYKNSQEQG----PRSSPAVSIKSVTK------PVVKEEKSANLLAK 5506 T ++L + +N IR+ I+EW PFE ++LLTI ANC+ L++ P+ D LE E FL IF VEA LK++A G H AYLRN WN++DF++VV G L +D + D++ LRA RVLRPL+LV+G PSLQVVL SII+AM PLL I LLVLF I I+AIIGLE + G H TC+ N + + + +P E+ PC+ + G G C CK W+GP +GIT+FDN +AMLTVFQCITMEGWTD++Y NDA+G + W+YFV LII+GSFF+LNLVLGVLSGEF+KERE+ + R F KLR +QQ E++ GY++WI +AE++ NE EDK R N S+P E E T+++ G G R R K + + +WR F R R VKS FYW VI LVF NT+ +A EHY Q WLT + A L LF EM++KMY L ++ YF S FN FDC ++ G + E I S G+SVLR +RLLRIFK+TRYW SL NLV SLLNS+RSI SLL LLFLFI+IF+LLGMQLFGG+FNF+E + ++ FD F ++LLTVFQILTGEDWN+VMY+GI + GG G + IYF++L + GNY LLNVFLAIAVDNLA+A+ LT+A++E+ E +R A E+K ++ P V+ S+ + S ++ ++D N +K P+ G ++ + P P + ++ K P+ SA FIFSP N R CH +VN F I+ I SSI+LAAEDPV+ S +N+IL DY FT +FT+E+ILK+ G LH GS+CR+ +NILD VV +L++F G + +N +K LRVLRVLRPL+ INR LK V CV +++ + NI+IV L QF+FA I VQLF+GK + C+D+SK + C+G + Y P + R W++ F FDN+L AM+ LFTV+T EGWP +L S++S D GPI +YR E++IF+I++ I+ FF +NIFV +I+TFQEQGE E + +LDKNQ+QC+++A+ +PL RY+PK++ +Y+VW +V ST FEY + V+I LNT+ L M++Y Q+ L + + LN FT +F++E +LK++AF PK YF DPWN+FDF+ VIGSI DV++SE +++S +S+ F RLFR RL+KLL +G IR LLWTFI+SF+ALPYV LLI MLFFIY++IGMQVFG I L +INR+NNFQTF +LLLFRCATGE+WQ+IMLAC K C + E +N+ + CGS+F YF+SF LC+FL++NLFVAVIMDNFDYLTRD SILGPHHLDE+ R+WAEYDP A GRI H ++ +LR ++PP+GFGK CP+R+A ++L+ MNMP++ +GTV F TLFAL+R +L IK T ++ + ELR I K+W + K L+ +VPP + ++TVGK YA +LI E +R +K +EQG P A+S+++ + P ++ S +L A+ Sbjct: 98 TRPPRALLCLTLKNPIRRACISIVEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIAYGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCY--NQEGI-IDVPAEEDPSPCA-LETGHG---RQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCITMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGDFQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEDKPR------------------NMSMPTSETESV----NTENVAGGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLTIASEHYNQPHWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFIVCGGILETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYGGPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLARTASPEKKQE---------VMEKPAVEESKEEKIELKSITADGESPPTTKINMDDLQPSENEDKSPHSNPDTAGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSPNNRFRLQCHRIVNDTIFTNLILFFILLSSISLAAEDPVQHTSFRNHILGNADYVFTSIFTLEIILKMTAYGAFLHKGSFCRNYFNILDLLVVSVSLISF--------------GIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGEVDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLRRYIPKNQH--QYKVWYVVNSTYFEYLMFVLILLNTICLAMQHY---------------GQSCL-FKIAMNILNMLFTGLFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVILSETNPAEHTQCSPSMSAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRIK--TEGNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGD---DEVTVGKFYATFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAE 1676
BLAST of Voltage dependent L type calcium channel subunit vs. Ensembl Mouse
Match: Cacna1c (calcium channel, voltage-dependent, L type, alpha 1C subunit [Source:MGI Symbol;Acc:MGI:103013]) HSP 1 Score: 1237.63 bits (3201), Expect = 0.000e+0 Identity = 763/1661 (45.94%), Postives = 1034/1661 (62.25%), Query Frame = 2 Query: 686 TSTSKSLFIFSEENVIRKYAKIIIEWGPFEYMVLLTILANCIVLSMERHLPKKDKTLLAGQLELTEKYFLGIFCVEALLKIVALGFCCHKEAYLRNVWNIMDFVVVVTGFLMMFLNIDNHSDSSTV--------DLRTLRAVRVLRPLKLVAGFPSLQVVLKSIIRAMAPLLQIGLLVLFAITIFAIIGLEFYSGAFHYTCFKANSDKLPLPIPTEKSLVPCSNSKNGSGLGAYTCPEDYQCKAYWEGPNYGITSFDNIGYAMLTVFQCITMEGWTDIMYHTNDAIGNRFNWLYFVPLIILGSFFMLNLVLGVLSGXXXXXXXXXXXXXXXLKLRRQQQTEKEFNGYMEWIQKAEEV-LLNEATTTSEDKMRIIAARRRAEKQKYKLLG-------KNQSIPDFEYEDTELYSETKSMKGNIFIRSYAGIR---RRRKERCTSFWRTEKHF-RFSVRRLVKSQPFYWAVIILVFFNTVCVAIEHYEQGKWLTLFLNYAEYVFLCLFMMEMMIKMYGLSIRVYFQSSFNIFDCVVIAGSLFEIIYGIFVQDSSFGLSVLRALRLLRIFKVTRYWAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXGMQLFGGEFNFEEGKPPQN-FDTFVKALLTVFQILTGEDWNTVMYNGIQSKGGVKERGTVFSIYFVLLVVFGNYTLLNVFLAIAVDNLANXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSSDNFIGRLPLSIDPPMVQVCPPSPQTANSLISKNFSFDHNQVEVNDKGCLLNTNK-PNGKLGMLGHDNTNFNSLESDPVPNKIEPETIQRK--PVLPYSAMFIFSPLNSLRRFCHFVVNLRYFDLFIMIVICASSIALAAEDPVKEKSLKNNILEFFDYAFTGVFTVEMILKIIDLGIILHPGSYCRDLWNILDATVVICALVAFIMGQKPSPTGNKLRGSSAKNLNTIKSLRVLRVLRPLKTINRVPKLKAVFDCVVSSLKNVFNILIVYILFQFIFAVIAVQLFQGKFFYCNDASKSSRETCRGYFFDYAGRST--PETKKRLWQHHDFHFDNILYAMLTLFTVTTGEGWPTVLKNSMESTNIDNGPIADYRQEMAXXXXXXXXXXXXXXXXXXXALIIITFQEQGENELIDLDLDKNQKQCIDFAINEKPLCRYMPKDKTTIKYRVWRLVVSTPFEYFIMVMIALNTLILMMKYYREEKKASSAATHDREQQAYLNYCNTLIFLNSAFTVMFSIECVLKIMAFGPKNYFRDPWNIFDFITVIGSITDVLVSE--------------LQDXXXXXXXXXXXXXXXXXXXXXXQGYTIRILLWTFIQSFKALPYVCLLIAMLFFIYSIIGMQVFGNIKLISEYQINRHNNFQTFTNGLLLLFRCATGESWQEIMLACDNNKPCEKDIENTNNFD----CGSNFTYIYFVSFIFLCSFLMLNLFVAVIMDNFDYLTRDSSILGPHHLDEYIRVWAEYDPGAIGRIHHSEMYEMLRNMEPPVGFGKKCPYRLAYRKLIRMNMPVDENGTVNFTTTLFALIRESLNIKMSTAEYMDIKDMELRQTICKMWPVQAKKKLNLIVPPDSELVFHKMTVGKIYAGYLIVENWRAYKNSQEQG----PRSSPAVSIKSVTK------PVVKEEKSANLLAK 5506 T ++L + +N IR+ I+EW PFE ++LLTI ANC+ L++ P+ D LE E FL IF VEA LK++A G H AYLRN WN++DF++VV G L +D + D++ LRA RVLRPL+LV+G PSLQVVL SII+AM PLL I LLVLF I I+AIIGLE + G H TC+ N + + + +P E+ PC+ + G G C CK W+GP +GIT+FDN +AMLTVFQCITMEGWTD++Y DA+G W+YFV L+I GSFF+LNLVLGVLSGEF+KERE+ + R F KLR +QQ E++ GY++WI +AE++ NE EDK R A QK + S+P E E T+++ G G R R K + + +WR F R R VKS FYW VI LVF NT+ +A EHY Q WLT + A L LF EM++KMY L ++ YF S FN FDC ++ G + E I S G+SVLR +RLLRIFK+TRYW SL NLV SLLNS+RSI SLL LLFLFI+IF+LLGMQLFGG+FNF+E + ++ FD F ++LLTVFQILTGEDWN+VMY+GI + GG G + IYF++L + GNY LLNVFLAIAVDNLA+A+ LT+A++E+ E +R A E+K ++ P V+ S+ + S ++ ++D N +K P+ G ++ + P P + ++ K P+ SA FIFSP N R CH +VN F I+ I SSI+LAAEDPV+ S +N+IL +FD FT +FT+E+ LK+ G LH GS+CR+ +NILD VV +L++F G + +N +K LRVLRVLRPL+ INR LK V CV +++ + NI+IV L QF+FA I VQLF+GK + C+D+SK + C+G + Y P + R W++ F FDN+L AM+ LFTV+T EGWP +L S++S D GPI +YR E++IF+I++ I+ FF +NIFV +I+TFQEQGE E + +LDKNQ+QC+++A+ +PL RY+PK++ +Y+VW +V ST FEY + V+I LNT+ L M++Y Q+ L + + LN FT +F++E +LK++AF PK YF DPWN+FDF+ VIGSI DV++SE +++S +S+ F RLFR RL+KLL +G IR LLWTFI+SF+ALPYV LLI MLFFIY++IGMQVFG I L +INR+NNFQTF +LLLFRCATGE+WQ+IMLAC K C + E +N+ + CGS+F YF+SF LC+FL++NLFVAVIMDNFDYLTRD SILGPHHLDE+ R+WAEYDP A GRI H ++ +LR ++PP+GFGK CP+R+A ++L+ MNMP++ +GTV F TLFAL+R +L IK T ++ + ELR I K+W + K L+ +VPP + ++TVGK YA +LI E +R +K +EQG P A+S+++ + P ++ S +L A+ Sbjct: 128 TRPPRALLCLTLKNPIRRACISIVEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIAYGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCY--NQEGI-IDVPAEEDPSPCA-LETGHG---RQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCITMEGWTDVLYWMQDAMGYELPWVYFVSLVIFGSFFVLNLVLGVLSGEFSKEREKAKARGDFQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEDKPRNRGAPAGLHDQKKGKFAWFSHSTETHVSMPTSETESV----NTENVAGGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLTIASEHYNQPHWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFIVCGGILETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYGGPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLARTASPEKKQE---------VMEKPAVEESKEEKIELKSITADGESPPTTKINMDDLQPSENEDKSPHSNPDTAGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSPNNRFRLQCHRIVNDTIFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALKMTAYGAFLHKGSFCRNYFNILDLLVVSVSLISF--------------GIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGEVDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLRRYIPKNQH--QYKVWYVVNSTYFEYLMFVLILLNTICLAMQHY---------------GQSCL-FKIAMNILNMLFTGLFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVILSETNPAEHTQCSPSMSAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRIK--TEGNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGD---DEVTVGKFYATFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAE 1731
BLAST of Voltage dependent L type calcium channel subunit vs. Ensembl Mouse
Match: Cacna1c (calcium channel, voltage-dependent, L type, alpha 1C subunit [Source:MGI Symbol;Acc:MGI:103013]) HSP 1 Score: 1237.63 bits (3201), Expect = 0.000e+0 Identity = 762/1654 (46.07%), Postives = 1031/1654 (62.33%), Query Frame = 2 Query: 686 TSTSKSLFIFSEENVIRKYAKIIIEWGPFEYMVLLTILANCIVLSMERHLPKKDKTLLAGQLELTEKYFLGIFCVEALLKIVALGFCCHKEAYLRNVWNIMDFVVVVTGFLMMFLNIDNHSDSSTV--------DLRTLRAVRVLRPLKLVAGFPSLQVVLKSIIRAMAPLLQIGLLVLFAITIFAIIGLEFYSGAFHYTCFKANSDKLPLPIPTEKSLVPCSNSKNGSGLGAYTCPEDYQCKAYWEGPNYGITSFDNIGYAMLTVFQCITMEGWTDIMYHTNDAIGNRFNWLYFVPLIILGSFFMLNLVLGVLSGXXXXXXXXXXXXXXXLKLRRQQQTEKEFNGYMEWIQKAEEV-LLNEATTTSEDKMRIIAARRRAEKQKYKLLGKNQSIPDFEYEDTELYSETKSMKGNIFIRSYAGIR---RRRKERCTSFWRTEKHF-RFSVRRLVKSQPFYWAVIILVFFNTVCVAIEHYEQGKWLTLFLNYAEYVFLCLFMMEMMIKMYGLSIRVYFQSSFNIFDCVVIAGSLFEIIYGIFVQDSSFGLSVLRALRLLRIFKVTRYWAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXGMQLFGGEFNFEEGKPPQN-FDTFVKALLTVFQILTGEDWNTVMYNGIQSKGGVKERGTVFSIYFVLLVVFGNYTLLNVFLAIAVDNLANXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSSDNFIGRLPLSIDPPMVQVCPPSPQTANSLISKNFSFDHNQVEVNDKGCLLNTNK-PNGKLGMLGHDNTNFNSLESDPVPNKIEPETIQRK--PVLPYSAMFIFSPLNSLRRFCHFVVNLRYFDLFIMIVICASSIALAAEDPVKEKSLKNNILEFFDYAFTGVFTVEMILKIIDLGIILHPGSYCRDLWNILDATVVICALVAFIMGQKPSPTGNKLRGSSAKNLNTIKSLRVLRVLRPLKTINRVPKLKAVFDCVVSSLKNVFNILIVYILFQFIFAVIAVQLFQGKFFYCNDASKSSRETCRGYFFDYAGRST--PETKKRLWQHHDFHFDNILYAMLTLFTVTTGEGWPTVLKNSMESTNIDNGPIADYRQEMAXXXXXXXXXXXXXXXXXXXALIIITFQEQGENELIDLDLDKNQKQCIDFAINEKPLCRYMPKDKTTIKYRVWRLVVSTPFEYFIMVMIALNTLILMMKYYREEKKASSAATHDREQQAYLNYCNTLIFLNSAFTVMFSIECVLKIMAFGPKNYFRDPWNIFDFITVIGSITDVLVSE--------------LQDXXXXXXXXXXXXXXXXXXXXXXQGYTIRILLWTFIQSFKALPYVCLLIAMLFFIYSIIGMQVFGNIKLISEYQINRHNNFQTFTNGLLLLFRCATGESWQEIMLACDNNKPCEKDIENTNNFD----CGSNFTYIYFVSFIFLCSFLMLNLFVAVIMDNFDYLTRDSSILGPHHLDEYIRVWAEYDPGAIGRIHHSEMYEMLRNMEPPVGFGKKCPYRLAYRKLIRMNMPVDENGTVNFTTTLFALIRESLNIKMSTAEYMDIKDMELRQTICKMWPVQAKKKLNLIVPPDSELVFHKMTVGKIYAGYLIVENWRAYKNSQEQG----PRSSPAVSIKSVTK------PVVKEEKSANLLAK 5506 T ++L + +N IR+ I+EW PFE ++LLTI ANC+ L++ P+ D LE E FL IF VEA LK++A G H AYLRN WN++DF++VV G L +D + D++ LRA RVLRPL+LV+G PSLQVVL SII+AM PLL I LLVLF I I+AIIGLE + G H TC+ N + + + +P E+ PC+ + G G C CK W+GP +GIT+FDN +AMLTVFQCITMEGWTD++Y DA+G W+YFV L+I GSFF+LNLVLGVLSGEF+KERE+ + R F KLR +QQ E++ GY++WI +AE++ NE EDK R N S+P E E T+++ G G R R K + + +WR F R R VKS FYW VI LVF NT+ +A EHY Q WLT + A L LF EM++KMY L ++ YF S FN FDC ++ G + E I S G+SVLR +RLLRIFK+TRYW SL NLV SLLNS+RSI SLL LLFLFI+IF+LLGMQLFGG+FNF+E + ++ FD F ++LLTVFQILTGEDWN+VMY+GI + GG G + IYF++L + GNY LLNVFLAIAVDNLA+A+ LT+A++E+ E +R A E+K ++ P V+ S+ + S ++ ++D N +K P+ G ++ + P P + ++ K P+ SA FIFSP N R CH +VN F I+ I SSI+LAAEDPV+ S +N+IL DY FT +FT+E+ILK+ G LH GS+CR+ +NILD VV +L++F G + +N +K LRVLRVLRPL+ INR LK V CV +++ + NI+IV L QF+FA I VQLF+GK + C+D+SK + C+G + Y P + R W++ F FDN+L AM+ LFTV+T EGWP +L S++S D GPI +YR E++IF+I++ I+ FF +NIFV +I+TFQEQGE E + +LDKNQ+QC+++A+ +PL RY+PK++ +Y+VW +V ST FEY + V+I LNT+ L M++Y Q+ L + + LN FT +F++E +LK++AF PK YF DPWN+FDF+ VIGSI DV++SE +++S +S+ F RLFR RL+KLL +G IR LLWTFI+SF+ALPYV LLI MLFFIY++IGMQVFG I L +INR+NNFQTF +LLLFRCATGE+WQ+IMLAC K C + E +N+ + CGS+F YF+SF LC+FL++NLFVAVIMDNFDYLTRD SILGPHHLDE+ R+WAEYDP A GRI H ++ +LR ++PP+GFGK CP+R+A ++L+ MNMP++ +GTV F TLFAL+R +L IK T ++ + ELR I K+W + K L+ +VPP + ++TVGK YA +LI E +R +K +EQG P A+S+++ + P ++ S +L A+ Sbjct: 98 TRPPRALLCLTLKNPIRRACISIVEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIAYGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCY--NQEGI-IDVPAEEDPSPCA-LETGHG---RQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCITMEGWTDVLYWMQDAMGYELPWVYFVSLVIFGSFFVLNLVLGVLSGEFSKEREKAKARGDFQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEDKPR------------------NMSMPTSETESV----NTENVAGGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLTIASEHYNQPHWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFIVCGGILETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYGGPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLARTASPEKKQE---------VMEKPAVEESKEEKIELKSITADGESPPTTKINMDDLQPSENEDKSPHSNPDTAGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSPNNRFRLQCHRIVNDTIFTNLILFFILLSSISLAAEDPVQHTSFRNHILGNADYVFTSIFTLEIILKMTAYGAFLHKGSFCRNYFNILDLLVVSVSLISF--------------GIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGEVDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLRRYIPKNQH--QYKVWYVVNSTYFEYLMFVLILLNTICLAMQHY---------------GQSCL-FKIAMNILNMLFTGLFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVILSETNPAEHTQCSPSMSAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRIK--TEGNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGD---DEVTVGKFYATFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAE 1676
BLAST of Voltage dependent L type calcium channel subunit vs. UniProt/SwissProt
Match: sp|C9D7C2|CAC1A_APIME (Voltage-dependent calcium channel type A subunit alpha-1 OS=Apis mellifera OX=7460 GN=CAC PE=2 SV=1) HSP 1 Score: 1695.25 bits (4389), Expect = 0.000e+0 Identity = 995/1734 (57.38%), Postives = 1216/1734 (70.13%), Query Frame = 2 Query: 695 SKSLFIFSEENVIRKYAKIIIEWGPFEYMVLLTILANCIVLSMERHLPKKDKTLLAGQLELTEKYFLGIFCVEALLKIVALGFCCHKEAYLRNVWNIMDFVVVVTGFLMMFLNIDNHSDSSTVDLRTLRAVRVLRPLKLVAGFPSLQVVLKSIIRAMAPLLQIGLLVLFAITIFAIIGLEFYSGAFHYTCFKANSDKLPLPIPTEKSLVPC-SNSKNGSGLGAYTCPEDYQ-CKAYWEGPNYGITSFDNIGYAMLTVFQCITMEGWTDIMYHTNDAIGNRFNWLYFVPLIILGSFFMLNLVLGVLSGXXXXXXXXXXXXXXXLKLRRQQQTEKEFNGYMEWIQKAEEVLLNEATTTSEDKMRIIAARRRAEKQKYKLLGKNQSIPDFEYEDTELYSETKSMKGNIFIRSYAGIRRRRKERCTSFWRTEKHFRFSVRRLVKSQPFYWAVIILVFFNTVCVAIEHYEQGKWLTLFLNYAEYVFLCLFMMEMMIKMYGLSIRVYFQSSFNIFDCVVIAGSLFEIIYGIFVQDSSFGLSVLRALRLLRIFKVTRYWAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXGMQLFGGEFNFEEGKPPQNFDTFVKALLTVFQILTGEDWNTVMYNGIQSKGGVKERGTVFSIYFVLLVVFGNYTLLNVFLAIAVDNLANXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSSDNFIGRLPLSIDPPMVQVCPPSPQTANSLISKNFSFDHNQVEVNDKGCLLNTNKPNGKLGMLGHDNTNFNSLESDPVPNKIEPETIQRKPVLPYSAMFIFSPLNSLRRFCHFVVNLRYFDLFIMIVICASSIALAAEDPVKEKSLKNNILEFFDYAFTGVFTVEMILKIIDLGIILHPGSYCRDLWNILDATVVICALVAFIMGQKPSPTGNKLRGSSA-KNLNTIKSLRVLRVLRPLKTINRVPKLKAVFDCVVSSLKNVFNILIVYILFQFIFAVIAVQLFQGKFFYCNDASKSSRETCRGYFFDYA-GRSTPETKKRLWQHHDFHFDNILYAMLTLFTVTTGEGWPTVLKNSMESTNIDNGPIADYRQEMAXXXXXXXXXXXXXXXXXXXALIIITFQEQGENELIDLDLDKNQKQCIDFAINEKPLCRYMPKDKTTIKYRVWRLVVSTPFEYFIMVMIALNTLILMMKYYREEKKASSAATHDREQQAYLNYCNTLIFLNSAFTVMFSIECVLKIMAFGPKNYFRDPWNIFDFITVIGSITDVLVSELQDXXXXXXXXXXXXXXXXXXXXXXQGYTIRILLWTFIQSFKALPYVCLLIAMLFFIYSIIGMQVFGNIKLISEYQINRHNNFQTFTNGLLLLFRCATGESWQEIMLACDNNKPCEKDIENTNNFDCGSNFTYIYFVSFIFLCSFLMLNLFVAVIMDNFDYLTRDSSILGPHHLDEYIRVWAEYDPGAIGRIHHSEMYEMLRNMEPPVGFGKKCPYRLAYRKLIRMNMPVDENGTVNFTTTLFALIRESLNIKMSTAEYMDIKDMELRQTICKMWPVQAKKKLNLIVPPDSELVFHKMTVGKIYAGYLIVENWRAYKNSQEQGPRSSPAVSIKSVTKPVVKEEKSANLLAKFFVAFKSNTNKSNISLDSHHERDEERFSIDHTYGE-DYDANRRYSYLRRGSKPRGSKEIYSDLTPTQDYSYGLRPEH-------------ATIPG-MPAPRKFGNRPRSPMYSLSELETKDRANTP 5839 + SLFI SE+N IRK+ + IIEW PFEY VLLTI+ANC+VL++E HLPK+DKT+LA +LE TE YFLGIFCVEA LKI+ALGF H+ +YLRN+WNIMDF VVVTGF+ F + +DLRTLRA+RVLRPLKLV+G PSLQVVLKSII+AMAPLLQIGLLVLFAI IFAIIGLEFYSG H TC+ + + + S PC +++K+ + GA+ C + C +WEGPN+GITSFDNIG+AMLTVFQCITMEGWT I+Y TNDA+G+ +NW+YF+PLI+LGSFFMLNLVLGVLSGEFAKERE+VE R++FLKLRRQQQ E E Y+ WI KAEEV+L E TT E+K I+ R+RAE +K KL + + E D + S + K C FW EK FR+ +R+ VKSQ FYW VI+LVFFNTVCVA+EHY Q +WLT FL +AE+VFL LFM+EM IK+Y L R YF SSFN FDCVVI+GS+FE+I+ V+ SFGLSVLRALRLLRIFKVT+YW SLRNLV+SLL+SMRSIISLLFLLFLFILIFALLGMQLFGG+FNF+ G PP NF+TF ALLTVFQILTGEDWN VMY GI+S+GG K +G ++S+YF++LV+FGNYTLLNVFLAIAVDNLANAQEL+AAE E+ E ++ + + + P P V++CPP NGK G + + D P KP+LPYS+MFI SP N +RR H+VVNLRYFD FIM+VI SSIALAAEDPV E S +N +L +FDYAFTGVFTVEMILKIIDLGIILHPGSY R+ WNI+DA VVICA V+F + GSSA +NL+TIKSLRVLRVLRPLKTI RVPKLKAVFDCVV+SLKNV NILIVYILFQFIFAVIAVQLF GKFFYC+D SK +++ C+G +F + G PE KKR WQ FH+DN++ AMLTLF V TGEGWP +L+NSM +T D GPI ++R EM+IFYIV+FIVFPFFFVNIFVALIIITFQEQGE EL D ++DKNQK CIDF I +PL RYMPK++ ++KY++WR+VVSTPFEYFIM +I LNT++LMMK++R+ Y NTL ++N FT MF++EC+LKI AFG +N+F+D WN FDFITVIGSI D LV E ++ A + L QGYTIRILLWTF+QSFKALPYVCLLIAMLFFIY+IIGMQVFGNI L ++ I +HNNFQ+F GL+LLFRCATGE+W IML+C +PC+ CGSN Y YFVSFIF CSFLMLNLFVAVIMDNFDYLTRDSSILG HHLDE++R+WAEYDP A G+IH++EMY+ML+NM+PP+GFG KCP RLAY+KLIRMNMPVD + VNFTTTLFALIRE+LNIK+ A + + ELR TI +WP+QAKK L+L++P + E+ KMTVGKIY LI+E+WR + Q + P + ++ V VV + ++ +L + + + H R S+ H+ G YD + Y + + G + S++ Q +++ P +T P P+P +R R Y + LE + R+ +P Sbjct: 145 TTSLFILSEDNCIRKHTRFIIEWPPFEYAVLLTIIANCVVLALEEHLPKQDKTILAQKLEATEIYFLGIFCVEASLKILALGFVLHRGSYLRNIWNIMDFFVVVTGFITAF----SQGIELDMDLRTLRAIRVLRPLKLVSGIPSLQVVLKSIIKAMAPLLQIGLLVLFAIVIFAIIGLEFYSGTLHKTCYSIRDINVIVKEGEQAS--PCNTDNKSEAPFGAHVCDANISTCMDHWEGPNFGITSFDNIGFAMLTVFQCITMEGWTAILYWTNDALGSTYNWIYFIPLIVLGSFFMLNLVLGVLSGEFAKEREKVENRQSFLKLRRQQQLEHELYCYLNWICKAEEVILAEERTTEEEKKHILEGRKRAEAKKKKLGKSKSTDTEEEEGDDDQDDGELSSS------------TKEKGPCKQFWLAEKRFRYWIRKSVKSQKFYWFVIVLVFFNTVCVAVEHYGQPQWLTDFLYFAEFVFLALFMLEMFIKVYALGPRTYFDSSFNRFDCVVISGSIFEVIWSE-VKSGSFGLSVLRALRLLRIFKVTKYWKSLRNLVISLLSSMRSIISLLFLLFLFILIFALLGMQLFGGQFNFDSGTPPTNFNTFPIALLTVFQILTGEDWNEVMYQGIESQGGHK-KGMIYSLYFIVLVLFGNYTLLNVFLAIAVDNLANAQELSAAENEEEEEDKQKQAQEIEKEIQSLQN------PKDGGAPKVEICPP----------------------------------NGKGGKQSSEEEKKQDEDDDTGP----------KPMLPYSSMFILSPTNPVRRAAHWVVNLRYFDFFIMVVISLSSIALAAEDPVWEDSPRNEVLNYFDYAFTGVFTVEMILKIIDLGIILHPGSYLREFWNIMDAVVVICAAVSFAF---------DMTGSSAGQNLSTIKSLRVLRVLRPLKTIKRVPKLKAVFDCVVNSLKNVINILIVYILFQFIFAVIAVQLFNGKFFYCSDESKYTQQDCQGQYFVFEDGALLPEPKKREWQSQFFHYDNVMAAMLTLFAVQTGEGWPQILQNSMAATYEDKGPIQNFRIEMSIFYIVYFIVFPFFFVNIFVALIIITFQEQGEAELQDGEIDKNQKSCIDFTIQARPLERYMPKERNSVKYKIWRIVVSTPFEYFIMGLIVLNTVLLMMKFHRQSDA----------------YKNTLKYMNMCFTGMFTVECILKIAAFGVRNFFKDAWNTFDFITVIGSIVDALVIEFGENFINVGFLRLFRAARLIKLLR-QGYTIRILLWTFVQSFKALPYVCLLIAMLFFIYAIIGMQVFGNIALDADTSITKHNNFQSFIQGLMLLFRCATGEAWPNIMLSCVKGRPCDAKAGKQEG-GCGSNIAYAYFVSFIFFCSFLMLNLFVAVIMDNFDYLTRDSSILGAHHLDEFVRIWAEYDPNATGKIHYTEMYDMLKNMDPPLGFGNKCPNRLAYKKLIRMNMPVDVDLKVNFTTTLFALIRENLNIKVRRASERNQANEELRDTIRSIWPLQAKKMLDLLIPRNEEIGRGKMTVGKIYVCLLILESWRTTRFGQIESA-GQPIMELQDV---VVSDSRAGSLES---LTHTGKRLHPPVQPVRHPSRSP---SLRHSPGRPGYDHHGHYYH-----EGPGFSDTVSNVVEIQRHTHHPHPSQYNHRHRMRGPWSASTSPARTPSPIHHIDRGRH--YGTTSLEQRSRSPSP 1764
BLAST of Voltage dependent L type calcium channel subunit vs. UniProt/SwissProt
Match: sp|Q02485|CAC1S_RAT (Voltage-dependent L-type calcium channel subunit alpha-1S OS=Rattus norvegicus OX=10116 GN=Cacna1s PE=1 SV=2) HSP 1 Score: 1238.4 bits (3203), Expect = 0.000e+0 Identity = 746/1633 (45.68%), Postives = 1026/1633 (62.83%), Query Frame = 2 Query: 641 SLAKRTINLSFPGMQTSTSKSLFIFSEENVIRKYAKIIIEWGPFEYMVLLTILANCIVLSMERHLPKKDKTLLAGQLELTEKYFLGIFCVEALLKIVALGFCCHKEAYLRNVWNIMDFVVVVTGFLMMFLNIDN---------HSDSSTVDLRTLRAVRVLRPLKLVAGFPSLQVVLKSIIRAMAPLLQIGLLVLFAITIFAIIGLEFYSGAFHYTCFKANSDKLPLPIPTEKSLVPCSNSKNGSGLGAYTCPEDYQCKAYWEGPNYGITSFDNIGYAMLTVFQCITMEGWTDIMYHTNDAIGNRFNWLYFVPLIILGSFFMLNLVLGVLSGXXXXXXXXXXXXXXXLKLRRQQQTEKEFNGYMEWIQKAEEVLLNEATTTSEDKMRIIAARRRAEKQKYKLLGKNQSIPDFEYEDTELYSETKSMKGNI-FIRSYAGIRRRRKERCTSFWRT-EKHFRFSVRRLVKSQPFYWAVIILVFFNTVCVAIEHYEQGKWLTLFLNYAEYVFLCLFMMEMMIKMYGLSIRVYFQSSFNIFDCVVIAGSLFEIIYGIFVQDSSFGLSVLRALRLLRIFKVTRYWAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXGMQLFGGEFNFEEGKPPQ-NFDTFVKALLTVFQILTGEDWNTVMYNGIQSKGGVKERGTVFSIYFVLLVVFGNYTLLNVFLAIAVDNLANXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSSDNFIGRLPLSIDPPMVQVCPPSPQTANSLISKNFSFDHNQVEVNDKGCLLNTNKPNGKLGMLGHDNTNFNSLESDPVPNKIEPETIQRK--PVLPYSAMFIFSPLNSLRRFCHFVVNLRYFDLFIMIVICASSIALAAEDPVKEKSLKNNILEFFDYAFTGVFTVEMILKIIDLGIILHPGSYCRDLWNILDATVVICALVAFIMGQKPSPTGNKLRGSSAKNLNTIKSLRVLRVLRPLKTINRVPKLKAVFDCVVSSLKNVFNILIVYILFQFIFAVIAVQLFQGKFFYCNDASKSSRETCRGYFFDYA-GRSTP-ETKKRLWQHHDFHFDNILYAMLTLFTVTTGEGWPTVLKNSMESTNIDNGPIADYRQEMAXXXXXXXXXXXXXXXXXXXALIIITFQEQGENELIDLDLDKNQKQCIDFAINEKPLCRYMPKDKTTIKYRVWRLVVSTPFEYFIMVMIALNTLILMMKYYREEKKASSAATHDREQQAYLNYCNTLIFLNSAFTVMFSIECVLKIMAFGPKNYFRDPWNIFDFITVIGSITDVLVSEL----------------------QDXXXXXXXXXXXXXXXXXXXXXXQGYTIRILLWTFIQSFKALPYVCLLIAMLFFIYSIIGMQVFGNIKLISEYQINRHNNFQTFTNGLLLLFRCATGESWQEIMLACDNNKPC--EKDIENTNNFDCGSNFTYIYFVSFIFLCSFLMLNLFVAVIMDNFDYLTRDSSILGPHHLDEYIRVWAEYDPGAIGRIHHSEMYEMLRNMEPPVGFGKKCPYRLAYRKLIRMNMPVDENGTVNFTTTLFALIRESLNIKMSTAEYMDIKDMELRQTICKMWPVQAKKKLNLIVPPDSELVFHKMTVGKIYAGYLIVENWRAYKNSQEQ 5419 L K+ P + ++LF + +N +RK ++EW PFE ++LLTI ANC+ L++ +P+ D L LE E +FL +F +EA +KI+A GF H++AYLR+ WN++DF++V G L N S + +D++ LRA RVLRPL+LV+G PSLQVVL SI +AM PL I LLVLF + I+AIIGLE + G H TC+ +D + T ++ P ++ GSG +C+ W GPN+GIT FDN G++MLTV+QCI+MEGWTD++Y NDAIGN + W+YFV LI+LGSFF+LNLVLGVLSGEF KERE+ + R F KLR +QQ E++ GYM WI + E + + E K+ + D DTE E + + I FIR WR + FR+ LVKS+ FYW VI++V NT+ +A EH+ Q WLT + A V L LF +EM++KMYGL +R YF S FN FDC V+ + EI+ + G+SVLR +RLLR+FK+T+YW SL NLV SLLNS+RSI SLL LLFLF++IFALLGMQLFGG ++FE+ + + NFD F +AL++VFQ+LTGEDWN+VMYNGI + GG G + IYF++L V GNY LLNVFLAIAVDNLA A+ LT+A++ KA E +R + L ++ + + + + L P + P TA I + F+ N EV D P G D + + + P P + ++ K P+ S+ FIFSP N +R CH +VN +F FI++ I SS ALAAEDP++ S++N ILE+FDY FT VFTVE++LK+ G LH GS+CR+ +NILD VV +L++ G + ++ +K LRVLRVLRPL+ INR LK V CV +++ + NI++V L QF+FA I VQLF+GKF+ CND SK + E CRGY++ Y G T E + R W H+DFHFDN+L AM++LFTV+T EGWP +L +++S D GP+ + R EMAIF+I++ I+ FF +NIFV +I+TFQEQGE E + +LDKNQ+QC+ +A+ +PL Y+PK+ +Y+VW +V S+ FEY + +I LNT+ L M++Y + ++ +N+ + + LN AFT++F++E +LK++AF P+ YF DPWN+FDF+ VIGSI DV++SE+ +S+ +S F RLFR RLIKLL + +R LLWTFI+SF+ALPYV LLI MLFFIY++IGMQ+FG I ++ QINR+NNFQTF +LLLFRCATGE+WQEI+LAC K C E D + CG+NF Y YF+SF LC+FL++NLFVAVIMDNFDYLTRD SILGPHHLDE+ +WAEYDP A GRI H ++ +LR ++PP+GFGK CP+R+A ++L+ MNMP++ +GTV F TLFAL+R +L IK T + + ELR I K+W + K L+ ++PP + ++TVGK YA +LI E++R + QE+ Sbjct: 10 GLRKKQPKKPVPEILPRPPRALFCLTLQNPLRKACISVVEWKPFETIILLTIFANCVALAVYLPMPEDDNNTLNLGLEKLEYFFLIVFSIEAAMKIIAYGFLFHQDAYLRSGWNVLDFIIVFLGVFTAILEQVNIIQTNTAPMSSKGAGLDVKALRAFRVLRPLRLVSGVPSLQVVLNSIFKAMLPLFHIALLVLFMVIIYAIIGLELFKGKMHKTCYFIGTDI----VATVENEKPSPCARTGSGRPCTI--NGSECRGGWPGPNHGITHFDNFGFSMLTVYQCISMEGWTDVLYWVNDAIGNEWPWIYFVTLILLGSFFILNLVLGVLSGEFTKEREKAKSRGTFQKLREKQQLEEDLRGYMSWITQGE---VMDVDDLREGKLSL----------------------DEGGSDTESLYEIEGLNKIIQFIRH---------------WRQWNRVFRWKCHDLVKSKVFYWLVILIVALNTLSIASEHHNQPLWLTHLQDVANRVLLALFTIEMLMKMYGLGLRQYFMSIFNRFDCFVVCSGILEILLVESGAMTPLGISVLRCIRLLRLFKITKYWTSLSNLVASLLNSIRSIASLLLLLFLFMIIFALLGMQLFGGRYDFEDTEVRRSNFDNFPQALISVFQVLTGEDWNSVMYNGIMAYGGPSYPGVLVCIYFIILFVCGNYILLNVFLAIAVDNLAEAESLTSAQKAKAEERKRRKMSRGLPDKSEEERSTMTK-KLEQKPKGEGI----PTTAKLKIDE---FESNVNEVKD---------PYPSADFPGDDEEDEPEIPASPRPRPLAELQLKEKAVPIPEASSFFIFSPTNKIRVLCHRIVNATWFTNFILLFILLSSAALAAEDPIRADSMRNQILEYFDYVFTAVFTVEIVLKMTTYGAFLHKGSFCRNYFNILDLLVVAVSLISM--------------GLESSAISVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVLVTTLLQFMFACIGVQLFKGKFYSCNDLSKMTEEECRGYYYIYKDGDPTQIELRPRQWIHNDFHFDNVLSAMMSLFTVSTFEGWPQLLYKAIDSNEEDTGPVYNNRVEMAIFFIIYIILIAFFMMNIFVGFVIVTFQEQGETEYKNCELDKNQRQCVQYALKARPLRCYIPKNP--YQYQVWYVVTSSYFEYLMFALIMLNTICLGMQHYNQSEQ--------------MNHISDI--LNVAFTIIFTLEMILKLIAFKPRGYFGDPWNVFDFLIVIGSIIDVILSEIDTLLASSGGLYCLGGGCGNVDPDESARISSAFFRLFRVMRLIKLLSRAEGVRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQMFGKIAMVDGTQINRNNNFQTFPQAVLLLFRCATGEAWQEILLACSYGKRCDPESDYAPGEEYACGTNFAYYYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKAIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKFCPHRVACKRLVGMNMPLNSDGTVTFNATLFALVRTALKIK--TEGNFEQANEELRAIIKKIWKRTSMKLLDQVIPPIGD---DEVTVGKFYATFLIQEHFRKFMKRQEE 1542
BLAST of Voltage dependent L type calcium channel subunit vs. UniProt/SwissProt
Match: sp|Q01815|CAC1C_MOUSE (Voltage-dependent L-type calcium channel subunit alpha-1C OS=Mus musculus OX=10090 GN=Cacna1c PE=1 SV=1) HSP 1 Score: 1237.63 bits (3201), Expect = 0.000e+0 Identity = 762/1654 (46.07%), Postives = 1031/1654 (62.33%), Query Frame = 2 Query: 686 TSTSKSLFIFSEENVIRKYAKIIIEWGPFEYMVLLTILANCIVLSMERHLPKKDKTLLAGQLELTEKYFLGIFCVEALLKIVALGFCCHKEAYLRNVWNIMDFVVVVTGFLMMFLNIDNHSDSSTV--------DLRTLRAVRVLRPLKLVAGFPSLQVVLKSIIRAMAPLLQIGLLVLFAITIFAIIGLEFYSGAFHYTCFKANSDKLPLPIPTEKSLVPCSNSKNGSGLGAYTCPEDYQCKAYWEGPNYGITSFDNIGYAMLTVFQCITMEGWTDIMYHTNDAIGNRFNWLYFVPLIILGSFFMLNLVLGVLSGXXXXXXXXXXXXXXXLKLRRQQQTEKEFNGYMEWIQKAEEV-LLNEATTTSEDKMRIIAARRRAEKQKYKLLGKNQSIPDFEYEDTELYSETKSMKGNIFIRSYAGIR---RRRKERCTSFWRTEKHF-RFSVRRLVKSQPFYWAVIILVFFNTVCVAIEHYEQGKWLTLFLNYAEYVFLCLFMMEMMIKMYGLSIRVYFQSSFNIFDCVVIAGSLFEIIYGIFVQDSSFGLSVLRALRLLRIFKVTRYWAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXGMQLFGGEFNFEEGKPPQN-FDTFVKALLTVFQILTGEDWNTVMYNGIQSKGGVKERGTVFSIYFVLLVVFGNYTLLNVFLAIAVDNLANXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSSDNFIGRLPLSIDPPMVQVCPPSPQTANSLISKNFSFDHNQVEVNDKGCLLNTNK-PNGKLGMLGHDNTNFNSLESDPVPNKIEPETIQRK--PVLPYSAMFIFSPLNSLRRFCHFVVNLRYFDLFIMIVICASSIALAAEDPVKEKSLKNNILEFFDYAFTGVFTVEMILKIIDLGIILHPGSYCRDLWNILDATVVICALVAFIMGQKPSPTGNKLRGSSAKNLNTIKSLRVLRVLRPLKTINRVPKLKAVFDCVVSSLKNVFNILIVYILFQFIFAVIAVQLFQGKFFYCNDASKSSRETCRGYFFDYAGRST--PETKKRLWQHHDFHFDNILYAMLTLFTVTTGEGWPTVLKNSMESTNIDNGPIADYRQEMAXXXXXXXXXXXXXXXXXXXALIIITFQEQGENELIDLDLDKNQKQCIDFAINEKPLCRYMPKDKTTIKYRVWRLVVSTPFEYFIMVMIALNTLILMMKYYREEKKASSAATHDREQQAYLNYCNTLIFLNSAFTVMFSIECVLKIMAFGPKNYFRDPWNIFDFITVIGSITDVLVSE--------------LQDXXXXXXXXXXXXXXXXXXXXXXQGYTIRILLWTFIQSFKALPYVCLLIAMLFFIYSIIGMQVFGNIKLISEYQINRHNNFQTFTNGLLLLFRCATGESWQEIMLACDNNKPCEKDIENTNNFD----CGSNFTYIYFVSFIFLCSFLMLNLFVAVIMDNFDYLTRDSSILGPHHLDEYIRVWAEYDPGAIGRIHHSEMYEMLRNMEPPVGFGKKCPYRLAYRKLIRMNMPVDENGTVNFTTTLFALIRESLNIKMSTAEYMDIKDMELRQTICKMWPVQAKKKLNLIVPPDSELVFHKMTVGKIYAGYLIVENWRAYKNSQEQG----PRSSPAVSIKSVTK------PVVKEEKSANLLAK 5506 T ++L + +N IR+ I+EW PFE ++LLTI ANC+ L++ P+ D LE E FL IF VEA LK++A G H AYLRN WN++DF++VV G L +D + D++ LRA RVLRPL+LV+G PSLQVVL SII+AM PLL I LLVLF I I+AIIGLE + G H TC+ N + + + +P E+ PC+ + G G C CK W+GP +GIT+FDN +AMLTVFQCITMEGWTD++Y DA+G W+YFV L+I GSFF+LNLVLGVLSGEF+KERE+ + R F KLR +QQ E++ GY++WI +AE++ NE EDK R N S+P E E T+++ G G R R K + + +WR F R R VKS FYW VI LVF NT+ +A EHY Q WLT + A L LF EM++KMY L ++ YF S FN FDC ++ G + E I S G+SVLR +RLLRIFK+TRYW SL NLV SLLNS+RSI SLL LLFLFI+IF+LLGMQLFGG+FNF+E + ++ FD F ++LLTVFQILTGEDWN+VMY+GI + GG G + IYF++L + GNY LLNVFLAIAVDNLA+A+ LT+A++E+ E +R A E+K ++ P V+ S+ + S ++ ++D N +K P+ G ++ + P P + ++ K P+ SA FIFSP N R CH +VN F I+ I SSI+LAAEDPV+ S +N+IL DY FT +FT+E+ILK+ G LH GS+CR+ +NILD VV +L++F G + +N +K LRVLRVLRPL+ INR LK V CV +++ + NI+IV L QF+FA I VQLF+GK + C+D+SK + C+G + Y P + R W++ F FDN+L AM+ LFTV+T EGWP +L S++S D GPI +YR E++IF+I++ I+ FF +NIFV +I+TFQEQGE E + +LDKNQ+QC+++A+ +PL RY+PK++ +Y+VW +V ST FEY + V+I LNT+ L M++Y Q+ L + + LN FT +F++E +LK++AF PK YF DPWN+FDF+ VIGSI DV++SE +++S +S+ F RLFR RL+KLL +G IR LLWTFI+SF+ALPYV LLI MLFFIY++IGMQVFG I L +INR+NNFQTF +LLLFRCATGE+WQ+IMLAC K C + E +N+ + CGS+F YF+SF LC+FL++NLFVAVIMDNFDYLTRD SILGPHHLDE+ R+WAEYDP A GRI H ++ +LR ++PP+GFGK CP+R+A ++L+ MNMP++ +GTV F TLFAL+R +L IK T ++ + ELR I K+W + K L+ +VPP + ++TVGK YA +LI E +R +K +EQG P A+S+++ + P ++ S +L A+ Sbjct: 98 TRPPRALLCLTLKNPIRRACISIVEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIAYGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCY--NQEGI-IDVPAEEDPSPCA-LETGHG---RQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCITMEGWTDVLYWMQDAMGYELPWVYFVSLVIFGSFFVLNLVLGVLSGEFSKEREKAKARGDFQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEDKPR------------------NMSMPTSETESV----NTENVAGGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLTIASEHYNQPHWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFIVCGGILETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYGGPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLARTASPEKKQE---------VMEKPAVEESKEEKIELKSITADGESPPTTKINMDDLQPSENEDKSPHSNPDTAGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSPNNRFRLQCHRIVNDTIFTNLILFFILLSSISLAAEDPVQHTSFRNHILGNADYVFTSIFTLEIILKMTAYGAFLHKGSFCRNYFNILDLLVVSVSLISF--------------GIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGEVDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLRRYIPKNQH--QYKVWYVVNSTYFEYLMFVLILLNTICLAMQHY---------------GQSCL-FKIAMNILNMLFTGLFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVILSETNPAEHTQCSPSMSAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRIK--TEGNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGD---DEVTVGKFYATFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAE 1676
BLAST of Voltage dependent L type calcium channel subunit vs. UniProt/SwissProt
Match: sp|P07293|CAC1S_RABIT (Voltage-dependent L-type calcium channel subunit alpha-1S OS=Oryctolagus cuniculus OX=9986 GN=CACNA1S PE=1 SV=1) HSP 1 Score: 1235.71 bits (3196), Expect = 0.000e+0 Identity = 749/1632 (45.89%), Postives = 1025/1632 (62.81%), Query Frame = 2 Query: 641 SLAKRTINLSFPGMQTSTSKSLFIFSEENVIRKYAKIIIEWGPFEYMVLLTILANCIVLSMERHLPKKDKTLLAGQLELTEKYFLGIFCVEALLKIVALGFCCHKEAYLRNVWNIMDFVVVVTGFLMMFLNIDNHSDSST---------VDLRTLRAVRVLRPLKLVAGFPSLQVVLKSIIRAMAPLLQIGLLVLFAITIFAIIGLEFYSGAFHYTCFKANSDKLPLPIPTEKSLVPCSNSKNGSGLGAYTCPEDYQCKAYWEGPNYGITSFDNIGYAMLTVFQCITMEGWTDIMYHTNDAIGNRFNWLYFVPLIILGSFFMLNLVLGVLSGXXXXXXXXXXXXXXXLKLRRQQQTEKEFNGYMEWIQKAEEVLLNEATTTSEDKMRIIAARRRAEKQKYKLLGKNQSIPDFEYEDTELYSETKSMKGNIFIRSYAGIRRRRKERCTSFWRT-EKHFRFSVRRLVKSQPFYWAVIILVFFNTVCVAIEHYEQGKWLTLFLNYAEYVFLCLFMMEMMIKMYGLSIRVYFQSSFNIFDCVVIAGSLFEIIYGIFVQDSSFGLSVLRALRLLRIFKVTRYWAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXGMQLFGGEFNFEEGKPPQ-NFDTFVKALLTVFQILTGEDWNTVMYNGIQSKGGVKERGTVFSIYFVLLVVFGNYTLLNVFLAIAVDNLANXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSSDNFIGRLPLSIDPPMVQVCPPSPQTANSLISKNFSFDHNQVEVNDKGCLLNTNKPNGKLGMLGHDNTNFNSLESDPVPNKIEPETIQRK--PVLPYSAMFIFSPLNSLRRFCHFVVNLRYFDLFIMIVICASSIALAAEDPVKEKSLKNNILEFFDYAFTGVFTVEMILKIIDLGIILHPGSYCRDLWNILDATVVICALVAFIMGQKPSPTGNKLRGSSAKNLNTIKSLRVLRVLRPLKTINRVPKLKAVFDCVVSSLKNVFNILIVYILFQFIFAVIAVQLFQGKFFYCNDASKSSRETCRGYFFDYA-GRSTP-ETKKRLWQHHDFHFDNILYAMLTLFTVTTGEGWPTVLKNSMESTNIDNGPIADYRQEMAXXXXXXXXXXXXXXXXXXXALIIITFQEQGENELIDLDLDKNQKQCIDFAINEKPLCRYMPKDKTTIKYRVWRLVVSTPFEYFIMVMIALNTLILMMKYYREEKKASSAATHDREQQAYLNYCNTLIFLNSAFTVMFSIECVLKIMAFGPKNYFRDPWNIFDFITVIGSITDVLVSEL----------------------QDXXXXXXXXXXXXXXXXXXXXXXQGYTIRILLWTFIQSFKALPYVCLLIAMLFFIYSIIGMQVFGNIKLISEYQINRHNNFQTFTNGLLLLFRCATGESWQEIMLACDNNKPC--EKDIENTNNFDCGSNFTYIYFVSFIFLCSFLMLNLFVAVIMDNFDYLTRDSSILGPHHLDEYIRVWAEYDPGAIGRIHHSEMYEMLRNMEPPVGFGKKCPYRLAYRKLIRMNMPVDENGTVNFTTTLFALIRESLNIKMSTAEYMDIKDMELRQTICKMWPVQAKKKLNLIVPPDSELVFHKMTVGKIYAGYLIVENWRAYKNSQEQ 5419 L K+ P + ++LF + +N +RK I+EW PFE ++LLTI ANC+ L++ +P+ D L LE E +FL +F +EA +KI+A GF H++AYLR+ WN++DF++V G L N S+T +D++ LRA RVLRPL+LV+G PSLQVVL SI +AM PL I LLVLF + I+AIIGLE + G H TC+ +D + T ++ P ++ GSG +C+ W GPN+GIT FDN G++MLTV+QCITMEGWTD++Y NDAIGN + W+YFV LI+LGSFF+LNLVLGVLSGEF KERE+ + R F KLR +QQ E++ GYM WI + E + + E K+ + E Y++ G N+ I FIR WR + FR+ LVKS+ FYW VI++V NT+ +A EH+ Q WLT + A V L LF +EM++KMYGL +R YF S FN FDC V+ + E++ + G+SVLR +RLLR+FK+T+YW SL NLV SLLNS+RSI SLL LLFLFI+IFALLGMQLFGG ++FE+ + + NFD F +AL++VFQ+LTGEDWN+VMYNGI + GG G + IYF++L V GNY LLNVFLAIAVDNLA A+ LT+A++ KA E +R + L ++ + + + + L P + P TA + + F+ N EV D P G D + + P P + ++ K P+ S+ FIFSP N +R CH +VN +F FI++ I SS ALAAEDP++ +S++N IL +FD AFT VFTVE++LK+ G LH GS+CR+ +NILD VV +L++ G + ++ +K LRVLRVLRPL+ INR LK V CV +++ + NI++V L QF+FA I VQLF+GKFF CND SK + E CRGY++ Y G T E + R W H+DFHFDN+L AM++LFTV+T EGWP +L +++S D GP+ + R EMAIF+I++ I+ FF +NIFV +I+TFQEQGE E + +LDKNQ+QC+ +A+ +PL Y+PK+ +Y+VW +V S+ FEY + +I LNT+ L M++Y H E+ +N+ + + LN AFT++F++E +LK++AF + YF DPWN+FDF+ VIGSI DV++SE+ +S+ +S F RLFR RLIKLL + +R LLWTFI+SF+ALPYV LLI MLFFIY++IGMQ+FG I L+ QINR+NNFQTF +LLLFRCATGE+WQEI+LAC K C E D + CG+NF Y YF+SF LC+FL++NLFVAVIMDNFDYLTRD SILGPHHLDE+ +WAEYDP A GRI H ++ +LR ++PP+GFGK CP+R+A ++L+ MNMP++ +GTV F TLFAL+R +L IK T + + ELR I K+W + K L+ ++PP + ++TVGK YA +LI E++R + QE+ Sbjct: 10 GLRKKQPKKPLPEVLPRPPRALFCLTLQNPLRKACISIVEWKPFETIILLTIFANCVALAVYLPMPEDDNNSLNLGLEKLEYFFLTVFSIEAAMKIIAYGFLFHQDAYLRSGWNVLDFIIVFLGVFTAILEQVNVIQSNTAPMSSKGAGLDVKALRAFRVLRPLRLVSGVPSLQVVLNSIFKAMLPLFHIALLVLFMVIIYAIIGLELFKGKMHKTCYYIGTDI----VATVENEKPSPCARTGSGRPCTI--NGSECRGGWPGPNHGITHFDNFGFSMLTVYQCITMEGWTDVLYWVNDAIGNEWPWIYFVTLILLGSFFILNLVLGVLSGEFTKEREKAKSRGTFQKLREKQQLEEDLRGYMSWITQGE---VMDVEDLREGKLSLEEGGSDTESL-YEIEGLNKIIQ--------------------FIRH---------------WRQWNRVFRWKCHDLVKSRVFYWLVILIVALNTLSIASEHHNQPLWLTHLQDIANRVLLSLFTIEMLLKMYGLGLRQYFMSIFNRFDCFVVCSGILELLLVESGAMTPLGISVLRCIRLLRLFKITKYWTSLSNLVASLLNSIRSIASLLLLLFLFIIIFALLGMQLFGGRYDFEDTEVRRSNFDNFPQALISVFQVLTGEDWNSVMYNGIMAYGGPSYPGVLVCIYFIILFVCGNYILLNVFLAIAVDNLAEAESLTSAQKAKAEERKRRKMSRGLPDKTEEEKSVMAK-KLEQKPKGEGI----PTTAKLKVDE---FESNVNEVKD---------PYPSADFPGDDEEDEPEIPVSPRPRPLAELQLKEKAVPIPEASSFFIFSPTNKVRVLCHRIVNATWFTNFILLFILLSSAALAAEDPIRAESVRNQILGYFDIAFTSVFTVEIVLKMTTYGAFLHKGSFCRNYFNILDLLVVAVSLISM--------------GLESSTISVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVLVTTLLQFMFACIGVQLFKGKFFSCNDLSKMTEEECRGYYYVYKDGDPTQMELRPRQWIHNDFHFDNVLSAMMSLFTVSTFEGWPQLLYRAIDSNEEDMGPVYNNRVEMAIFFIIYIILIAFFMMNIFVGFVIVTFQEQGETEYKNCELDKNQRQCVQYALKARPLRCYIPKNP--YQYQVWYVVTSSYFEYLMFALIMLNTICLGMQHY-----------HQSEE---MNHISDI--LNVAFTIIFTLEMILKLLAFKARGYFGDPWNVFDFLIVIGSIIDVILSEIDTFLASSGGLYCLGGGCGNVDPDESARISSAFFRLFRVMRLIKLLSRAEGVRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQMFGKIALVDGTQINRNNNFQTFPQAVLLLFRCATGEAWQEILLACSYGKLCDPESDYAPGEEYTCGTNFAYYYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKAIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKFCPHRVACKRLVGMNMPLNSDGTVTFNATLFALVRTALKIK--TEGNFEQANEELRAIIKKIWKRTSMKLLDQVIPPIGD---DEVTVGKFYATFLIQEHFRKFMKRQEE 1542
BLAST of Voltage dependent L type calcium channel subunit vs. UniProt/SwissProt
Match: sp|Q02789|CAC1S_MOUSE (Voltage-dependent L-type calcium channel subunit alpha-1S OS=Mus musculus OX=10090 GN=Cacna1s PE=1 SV=2) HSP 1 Score: 1232.62 bits (3188), Expect = 0.000e+0 Identity = 748/1634 (45.78%), Postives = 1022/1634 (62.55%), Query Frame = 2 Query: 638 RSLAKRTINLSFPGMQTSTSKSLFIFSEENVIRKYAKIIIEWGPFEYMVLLTILANCIVLSMERHLPKKDKTLLAGQLELTEKYFLGIFCVEALLKIVALGFCCHKEAYLRNVWNIMDFVVVVTGFLMMFLNIDN---------HSDSSTVDLRTLRAVRVLRPLKLVAGFPSLQVVLKSIIRAMAPLLQIGLLVLFAITIFAIIGLEFYSGAFHYTCFKANSDKLPLPIPTEKSLVPCSNSKNGSGLGAYTCPEDYQCKAYWEGPNYGITSFDNIGYAMLTVFQCITMEGWTDIMYHTNDAIGNRFNWLYFVPLIILGSFFMLNLVLGVLSGXXXXXXXXXXXXXXXLKLRRQQQTEKEFNGYMEWIQKAEEVLLNEATTTSEDKMRIIAARRRAEKQKYKLLGKNQSIPDFEYEDTELYSETKSMKGNI-FIRSYAGIRRRRKERCTSFWRT-EKHFRFSVRRLVKSQPFYWAVIILVFFNTVCVAIEHYEQGKWLTLFLNYAEYVFLCLFMMEMMIKMYGLSIRVYFQSSFNIFDCVVIAGSLFEIIYGIFVQDSSFGLSVLRALRLLRIFKVTRYWAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXGMQLFGGEFNFEEGKPPQ-NFDTFVKALLTVFQILTGEDWNTVMYNGIQSKGGVKERGTVFSIYFVLLVVFGNYTLLNVFLAIAVDNLANXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSSDNFIGRLPLSIDPPMVQVCPPSPQTANSLISKNFSFDHNQVEVNDKGCLLNTNKPNGKLGMLGHDNTNFNSLESDPVPNKIEPETIQRK--PVLPYSAMFIFSPLNSLRRFCHFVVNLRYFDLFIMIVICASSIALAAEDPVKEKSLKNNILEFFDYAFTGVFTVEMILKIIDLGIILHPGSYCRDLWNILDATVVICALVAFIMGQKPSPTGNKLRGSSAKNLNTIKSLRVLRVLRPLKTINRVPKLKAVFDCVVSSLKNVFNILIVYILFQFIFAVIAVQLFQGKFFYCNDASKSSRETCRGYFFDYA-GRSTP-ETKKRLWQHHDFHFDNILYAMLTLFTVTTGEGWPTVLKNSMESTNIDNGPIADYRQEMAXXXXXXXXXXXXXXXXXXXALIIITFQEQGENELIDLDLDKNQKQCIDFAINEKPLCRYMPKDKTTIKYRVWRLVVSTPFEYFIMVMIALNTLILMMKYYREEKKASSAATHDREQQAYLNYCNTLIFLNSAFTVMFSIECVLKIMAFGPKNYFRDPWNIFDFITVIGSITDVLVSEL----------------------QDXXXXXXXXXXXXXXXXXXXXXXQGYTIRILLWTFIQSFKALPYVCLLIAMLFFIYSIIGMQVFGNIKLISEYQINRHNNFQTFTNGLLLLFRCATGESWQEIMLACDNNKPC--EKDIENTNNFDCGSNFTYIYFVSFIFLCSFLMLNLFVAVIMDNFDYLTRDSSILGPHHLDEYIRVWAEYDPGAIGRIHHSEMYEMLRNMEPPVGFGKKCPYRLAYRKLIRMNMPVDENGTVNFTTTLFALIRESLNIKMSTAEYMDIKDMELRQTICKMWPVQAKKKLNLIVPPDSELVFHKMTVGKIYAGYLIVENWRAYKNSQEQ 5419 L K+ P + ++LF + +N +RK I+EW PFE ++LLTI ANC+ L++ +P+ D L LE E +FL +F +EA +KI+A GF H++AYLR+ WN++DF++V G + L N S + +D++ LRA RVLRPL+LV+G PSLQVVL SI +AM PL I LLVLF + I+AIIGLE + G H TC+ +D + T ++ P ++ GSG +C+ W GPN+GIT FDN G++MLTV+QCI+MEGWTD++Y NDAIGN + W+YFV LI+LGSFF+LNLVLGVLSGEF KERE+ + R F KLR +QQ E++ GYM WI + E + + E K+ + D DTE E + + I FIR WR + FR+ LVKS+ FYW VI++V NT+ +A EH+ Q WLT + A V L LF +EM++KMYGL +R YF S FN FDC V+ + EI+ S G+SVLR +RLLR+FK+T+YW SL NLV SLLNS+RSI SLL LLFLFI+IFALLGMQLFGG ++FE+ + + NFD F +AL++VFQ+LTGEDWN+VMYNGI + GG G + IYF++L V GNY LLNVFLAIAVDNLA A+ LT+A++ KA E +R + L ++ + R ++ P TA I + F+ N EV D P G D + + P P + ++ K P+ S+ FIFSP N +R CH +VN +F FI++ I SS ALAAEDP++ S++N ILE+FDY FT VFTVE++LK+ G LH GS+CR+ +NILD VV +L++ G + ++ +K LRVLRVLRPL+ INR LK V CV +++ + NI++V L QF+FA I VQLF+GKF+ CND SK + E CRGY++ Y G T E + R W H+DFHFDN+L AM++LFTV+T EGWP +L +++S D GP+ + R EMAIF+I++ I+ FF +NIFV +I+TFQEQGE E + +LDKNQ+QC+ +A+ +PL Y+PK+ +Y+VW +V S+ FEY + +I LNT+ L M++Y + ++ +N+ + + LN AFT++F++E VLK++AF P+ YF DPWN+FDF+ VIGSI DV++SE+ +S+ +S F RLFR RL+KLL + +R LLWTFI+SF+ALPYV LLI MLFFIY++IGMQ+FG I ++ QINR+NNFQTF +LLLFRCATGE+WQEI+LAC K C E D CG+NF Y YF+SF LC+FL++NLFVAVIMDNFDYLTRD SILGPHHLDE+ +WAEYDP A GRI H ++ +LR ++PP+GFGK CP+R+A ++L+ MNMP++ +GTV F TLFAL+R +L IK T + + ELR I K+W + K L+ ++PP + ++TVGK YA +LI E++R + QE+ Sbjct: 9 EGLRKKQPKKPVPEILPRPPRALFCLTLQNPLRKACISIVEWKPFETIILLTIFANCVALAVYLPMPEDDNNTLNLGLEKLEYFFLIVFSIEAAMKIIAYGFLFHQDAYLRSGWNVLDFIIVFLGVFTVILEQVNIIQTNTAPMSSKGAGLDVKALRAFRVLRPLRLVSGVPSLQVVLNSIFKAMLPLFHIALLVLFMVIIYAIIGLELFKGKMHKTCYFIGTDI----VATVENEKPSPCARTGSGRPCTI--NGSECRGGWPGPNHGITHFDNFGFSMLTVYQCISMEGWTDVLYWVNDAIGNEWPWIYFVTLILLGSFFILNLVLGVLSGEFTKEREKAKSRGTFQKLREKQQLEEDLRGYMSWITQGE---VMDVDDLREGKLSL----------------------DEGGSDTESLYEIEGLNKIIQFIRH---------------WRQWNRVFRWKCHDLVKSKVFYWLVILIVALNTLSIASEHHNQPLWLTHLQDVANRVLLTLFTIEMLMKMYGLGLRQYFMSIFNRFDCFVVCSGILEILLVESGAMSPLGISVLRCIRLLRLFKITKYWTSLSNLVASLLNSIRSIASLLLLLFLFIIIFALLGMQLFGGRYDFEDTEVRRSNFDNFPQALISVFQVLTGEDWNSVMYNGIMAYGGPTYPGVLVCIYFIILFVCGNYILLNVFLAIAVDNLAEAESLTSAQKAKAEERKRRKMSKGLPDKSEEE-----RATVTKKLEQKSKGEGIPTTAKLKIDE---FESNVNEVKD---------PYPSADFPGDDEEDEPEIPVSPRPRPLAELQLKEKAVPIPEASSFFIFSPTNKIRVLCHRIVNATWFTNFILLFILLSSAALAAEDPIRADSMRNQILEYFDYVFTAVFTVEIVLKMTTYGAFLHKGSFCRNYFNILDLLVVAVSLISM--------------GLESSAISVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVLVTTLLQFMFACIGVQLFKGKFYSCNDLSKMTEEECRGYYYIYKDGDPTQIELRPRQWIHNDFHFDNVLSAMMSLFTVSTFEGWPQLLYKAIDSNEEDTGPVYNNRVEMAIFFIIYIILIAFFMMNIFVGFVIVTFQEQGETEYKNCELDKNQRQCVQYALKARPLRCYIPKNP--YQYQVWYVVTSSYFEYLMFALIMLNTICLGMQHYNQSEQ--------------MNHISDI--LNVAFTIIFTLEMVLKLIAFKPRAYFGDPWNVFDFLIVIGSIIDVILSEIDTFLASSGGLYCLGGGCGNVDPDESARISSAFFRLFRVMRLVKLLNRAEGVRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQMFGKIAMVDGTQINRNNNFQTFPQAVLLLFRCATGEAWQEILLACSYGKLCDPESDYAPGEEHTCGTNFAYYYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKAIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKFCPHRVACKRLVGMNMPLNSDGTVTFNATLFALVRTALKIK--TEGNFEQANEELRAIIKKIWKRTSMKLLDQVIPPIGD---DEVTVGKFYATFLIQEHFRKFMKRQEE 1542
BLAST of Voltage dependent L type calcium channel subunit vs. TrEMBL
Match: A0A4Z2CWT3 (Voltage-dependent calcium channel type A subunit alpha-1 OS=Schistosoma japonicum OX=6182 GN=EWB00_006874 PE=3 SV=1) HSP 1 Score: 2102.02 bits (5445), Expect = 0.000e+0 Identity = 1166/1676 (69.57%), Postives = 1340/1676 (79.95%), Query Frame = 2 Query: 623 KTTSMRSLAKRTINLSFPGMQTSTSKSLFIFSEENVIRKYAKIIIEWGPFEYMVLLTILANCIVLSMERHLPKKDKTLLAGQLELTEKYFLGIFCVEALLKIVALGFCCHKEAYLRNVWNIMDFVVVVTGFLMMFLNIDNHSDSSTVDLRTLRAVRVLRPLKLVAGFPSLQVVLKSIIRAMAPLLQIGLLVLFAITIFAIIGLEFYSGAFHYTCFKA-NSDKLPLPIPTEKSLVPCSNSKNGSGL-------GAYTCPEDYQCKAYWEGPNYGITSFDNIGYAMLTVFQCITMEGWTDIMYHTNDAIGNRFNWLYFVPLIILGSFFMLNLVLGVLSGXXXXXXXXXXXXXXXLKLRRQQQTEKEFNGYMEWIQKAEEVLLNEATTTSEDKMRIIAARRRAEKQKYKLLGKNQSIPDFEYEDTELYSETKSMKGNIFIRSYAGIRRRRKERCTSFWRTEKHFRFSVRRLVKSQPFYWAVIILVFFNTVCVAIEHYEQGKWLTLFLNYAEYVFLCLFMMEMMIKMYGLSIRVYFQSSFNIFDCVVIAGSLFEIIYGIFVQDSSFGLSVLRALRLLRIFKVTRYWAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXGMQLFGGEFNFEEGKPPQNFDTFVKALLTVFQILTGEDWNTVMYNGIQSKGGVKERGTVFSIYFVLLVVFGNYTLLNVFLAIAVDNLANXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSSDNFIGRLPLSIDPPMVQVCPPSPQTANSLISKNFSFDHNQVEVNDKGCLLNTNKPNGKLGMLG--HDNTNFN--------SLESDPVPNKIEPETIQRKPVLPYSAMFIFSPLNSLRRFCHFVVNLRYFDLFIMIVICASSIALAAEDPVKEKSLKNNILEFFDYAFTGVFTVEMILKIIDLGIILHPGSYCRDLWNILDATVVICALVAFIMGQKPSPTGNKLRGSSAKNLNTIKSLRVLRVLRPLKTINRVPKLKAVFDCVVSSLKNVFNILIVYILFQFIFAVIAVQLFQGKFFYCNDASKSSRETCRGYFFDYAGRSTPETKKRLWQHHDFHFDNILYAMLTLFTVTTGEGWPTVLKNSMESTNIDNGPIADYRQEMAXXXXXXXXXXXXXXXXXXXALIIITFQEQGENELIDLDLDKNQKQCIDFAINEKPLCRYMPKDKTTIKYRVWRLVVSTPFEYFIMVMIALNTLILMMKYYREEKKASSAATHDREQQAYLNYCNTLIFLNSAFTVMFSIECVLKIMAFGPKNYFRDPWNIFDFITVIGSITDVLVSELQDXXXXXXXXXXXXXXXXXXXXXXQGYTIRILLWTFIQSFKALPYVCLLIAMLFFIYSIIGMQVFGNIKLISEYQINRHNNFQTFTNGLLLLFRCATGESWQEIMLACDNNKPCEKDIENTNNFDCGSNFTYIYFVSFIFLCSFLMLNLFVAVIMDNFDYLTRDSSILGPHHLDEYIRVWAEYDPGAIGRIHHSEMYEMLRNMEPPVGFGKKCPYRLAYRKLIRMNMPVDENGTVNFTTTLFALIRESLNIKMSTAEYMDIKDMELRQTICKMWPVQAKKKLNLIVPPDSELVFHKMTVGKIYAGYLIVENWRAYKNSQEQGPRSSPAVSIKSVTKPVVKEEKSANLLAKFFVAFKSNTNKSNISLDSHHERDEERFSID 5596 K +MR+LA+RT+ + PG+ S+ K+LFIFSEEN IRKY+KIIIEWGPFEYMVL TILANCIVL+ME HLP DKT L+ +LE TE YFL IFCVEALLKIVALGF H+ AYLRN+WNIMDF+VVVTG L L ++ +RA+RVLRPLKLV GF SLQ+VLKSIIRAMAPLLQI LLVLFAI IFAIIGLEFYSG FH TCF N D LPL +P SL PCS S NGS GA+ CP +Y CK YWEGPNYGITSFDNIGYAMLTVFQCITMEGWT+IMY TNDA G+RFN+LYFVPLIILGSFFMLNLVLGVLSGEFAKERERVEKRRAFLKLRRQQQTEKEFNGYM+WIQKAEEV+L E TTT++++MRII+ARRRA KQ+ K GK+ S D +ED+EL++E+KS SY + +RRKERC WR EK R+++RR+VKSQPFYW VIILVF NTVC AIEH+ Q WL+ FL YAE+VFL LF+ EM++K+YGL++R+YF+SSFNIFDCVVI GSLFEII+G F D+SFG+SVLRALRLLRIFKVTRYWASLRNLVLSLLNSMRSI+SLLFLLFLFILIFALLGMQLFGG+FNF+EG+P QNFDTFVKALLTVFQILTGEDWNT+MYNGI+++GGV G ++S+YFV+++VFGNYTLLNVFLAIAVDNLANAQELT AEEE+A + A D S + + QT +LI ++N+ V+D + N G DN FN SLESD IQ KPVLPYS+MFIF+P N++RRFCHFVVNLRYFDLFIMIVICASSIALAAEDP+ E+S +N ILE FDYAFTGVFT+E+ILK+IDLG++LHPGSY RD WNILDA VV ALVAF++ + + G +SAKNLNTIKSLRVLRVLRPLKTINRVPKLKAVFDCV+SSLKNVFNILIVY LFQFIFAVIAVQLFQGKFFYCND SK +R+ C+G F DY R P + R W+ DF++DN+++A+LTLFTVTTGEGWP VLKNS++ST D GP D+RQEMAIFY+VFFIVFPFFFVNIFVALIIITFQ QGENELI++DLDKNQK+CIDFAIN +PLCRYMPKD+ ++KYRVWRLVVSTPFEY+IMVMIA+NTLILMMKY+R+E+K+ A+ D EQQAY NYCNTL++ NSAFTVMFS+EC+LKIMAFGPKNYFRD WNIFDFITVIGSITDVLVSELQ+S+FLSLGFLRLFRAARLIKLLRQGY+IRI+LWTFIQS KALPYVCLLI MLFFIY I+GMQVFGNIK Q+N HNNFQTF +G+LLLFRCATGE+WQEIML C K CE E+ CGS++TY+YF +F FLCSF+MLNLFVAVIMDNFDYLTRDSSILGPHHLDE++RVWAEYDPGA G IHH ++YEMLRNMEPPVGFGK CPYRLAYRKLIRMNMPVDE G V+FTTTL ALIRESL IK E MD +DMELR+TICK+WPV KK L+L+VPPDSEL++HKMTVGKIYA YLI+ENWRA + +G S KSA++LA+FF A K NT+ NI+ E ++E+ S+D Sbjct: 166 KDETMRNLARRTLAIGIPGLHPSSHKTLFIFSEENAIRKYSKIIIEWGPFEYMVLSTILANCIVLAMEMHLPSNDKTTLSEKLEQTETYFLIIFCVEALLKIVALGFAFHRNAYLRNIWNIMDFIVVVTGLLAYIL--------PNLNQPAVRALRVLRPLKLVTGFESLQIVLKSIIRAMAPLLQISLLVLFAIIIFAIIGLEFYSGGFHMTCFDLYNPDYLPLSLPNRPSLAPCSLS-NGSATSTGSVPHGAFVCPTNYVCKGYWEGPNYGITSFDNIGYAMLTVFQCITMEGWTEIMYSTNDAFGDRFNYLYFVPLIILGSFFMLNLVLGVLSGEFAKERERVEKRRAFLKLRRQQQTEKEFNGYMDWIQKAEEVILAEDTTTADERMRIISARRRAAKQRLKQTGKDPSFNDSNFEDSELFAESKSHS------SYGDLLKRRKERCQGCWRREKRIRYAIRRMVKSQPFYWVVIILVFLNTVCGAIEHHGQPVWLSTFLYYAEFVFLGLFITEMLLKVYGLNVRIYFESSFNIFDCVVIIGSLFEIIWGFFHPDTSFGISVLRALRLLRIFKVTRYWASLRNLVLSLLNSMRSILSLLFLLFLFILIFALLGMQLFGGDFNFDEGRPTQNFDTFVKALLTVFQILTGEDWNTIMYNGIRAQGGVTGGGAIYSVYFVVVMVFGNYTLLNVFLAIAVDNLANAQELTEAEEEQAKLQEEIHLAEESAEMRSLVD------AKSNNNNNNNGNIKNIQTTGNLID-----NYNKSNVHDAANTIQENLNENNQNRTGVKRDNFMFNHMSNLNFTSLESDDTAKLQGSSQIQGKPVLPYSSMFIFAPTNAIRRFCHFVVNLRYFDLFIMIVICASSIALAAEDPISEQSKRNTILEHFDYAFTGVFTIELILKVIDLGVVLHPGSYFRDTWNILDAIVVFFALVAFVV-RSATSLGRIGTSTSAKNLNTIKSLRVLRVLRPLKTINRVPKLKAVFDCVISSLKNVFNILIVYWLFQFIFAVIAVQLFQGKFFYCNDVSKVTRDDCQGQFIDYNERGDPFLQNRTWRTRDFNYDNVIHAILTLFTVTTGEGWPAVLKNSIDSTVADRGPTPDFRQEMAIFYVVFFIVFPFFFVNIFVALIIITFQNQGENELIEMDLDKNQKRCIDFAINARPLCRYMPKDRRSMKYRVWRLVVSTPFEYYIMVMIAINTLILMMKYHRQEQKSYFTASVDIEQQAYHNYCNTLLYFNSAFTVMFSVECMLKIMAFGPKNYFRDRWNIFDFITVIGSITDVLVSELQESAFLSLGFLRLFRAARLIKLLRQGYSIRIILWTFIQSIKALPYVCLLITMLFFIYCIVGMQVFGNIKTDPHSQLNNHNNFQTFGDGILLLFRCATGENWQEIMLDCAAGKECEGSGES-----CGSSYTYLYFSTFNFLCSFIMLNLFVAVIMDNFDYLTRDSSILGPHHLDEFVRVWAEYDPGAKGLIHHRDVYEMLRNMEPPVGFGKNCPYRLAYRKLIRMNMPVDETGCVHFTTTLLALIRESLGIKTGPTEIMDQRDMELRETICKLWPVHGKKMLHLLVPPDSELLYHKMTVGKIYASYLIIENWRATRAFHGKGGTS-----------------KSASILARFFGAVKQNTHHPNIN----SETEDEKGSLD 1788
BLAST of Voltage dependent L type calcium channel subunit vs. TrEMBL
Match: A0A4E0RL13 (Voltage dependent L type calcium channel subunit OS=Fasciola hepatica OX=6192 GN=D915_000024 PE=3 SV=1) HSP 1 Score: 2100.48 bits (5441), Expect = 0.000e+0 Identity = 1146/1666 (68.79%), Postives = 1333/1666 (80.01%), Query Frame = 2 Query: 605 SIDDGSKTTSMRSLAKRTINLSFPGMQTSTSKSLFIFSEENVIRKYAKIIIEWGPFEYMVLLTILANCIVLSMERHLPKKDKTLLAGQLELTEKYFLGIFCVEALLKIVALGFCCHKEAYLRNVWNIMDFVVVVTGFLMMFLNIDNHSDSSTVDLRTLRAVRVLRPLKLVAGFPSLQVVLKSIIRAMAPLLQIGLLVLFAITIFAIIGLEFYSGAFHYTCFKANS-DKLPLPIPTEKSLVPCS----NSKNGSGL--GAYTCPEDYQCKAYWEGPNYGITSFDNIGYAMLTVFQCITMEGWTDIMYHTNDAIGNRFNWLYFVPLIILGSFFMLNLVLGVLSGXXXXXXXXXXXXXXXLKLRRQQQTEKEFNGYMEWIQKAEEVLLNEATTTSEDKMRIIAARRRAEKQKYKLLGKNQSIPDFEYEDTELYSETKSMKGNIFIRSYAGIRRRRKERCTSFWRTEKHFRFSVRRLVKSQPFYWAVIILVFFNTVCVAIEHYEQGKWLTLFLNYAEYVFLCLFMMEMMIKMYGLSIRVYFQSSFNIFDCVVIAGSLFEIIYGIFVQDSSFGLSVLRALRLLRIFKVTRYWAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXGMQLFGGEFNFEEGKPPQNFDTFVKALLTVFQILTGEDWNTVMYNGIQSKGGVKERGTVFSIYFVLLVVFGNYTLLNVFLAIAVDNLANXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSSDNFIGRL--PLSIDPPMVQVCPPSPQTANSLISKNFSFDHNQVEVNDKGCLLNTNK-PNGKLGMLGHDNTNFNSLESDPVPN-KIEPETIQRKPVLPYSAMFIFSPLNSLRRFCHFVVNLRYFDLFIMIVICASSIALAAEDPVKEKSLKNNILEFFDYAFTGVFTVEMILKIIDLGIILHPGSYCRDLWNILDATVVICALVAFIMGQKPSPTGNKLRGSSAKNLNTIKSLRVLRVLRPLKTINRVPKLKAVFDCVVSSLKNVFNILIVYILFQFIFAVIAVQLFQGKFFYCNDASKSSRETCRGYFFDYAGRSTPETKKRLWQHHDFHFDNILYAMLTLFTVTTGEGWPTVLKNSMESTNIDNGPIADYRQEMAXXXXXXXXXXXXXXXXXXXALIIITFQEQGENELIDLDLDKNQKQCIDFAINEKPLCRYMPKDKTTIKYRVWRLVVSTPFEYFIMVMIALNTLILMMKYYREEKKASSAATHDREQQAYLNYCNTLIFLNSAFTVMFSIECVLKIMAFGPKNYFRDPWNIFDFITVIGSITDVLVSELQDXXXXXXXXXXXXXXXXXXXXXXQGYTIRILLWTFIQSFKALPYVCLLIAMLFFIYSIIGMQVFGNIKLISEYQINRHNNFQTFTNGLLLLFRCATGESWQEIMLACDNNKPCEKDIENTNNFDCGSNFTYIYFVSFIFLCSFLMLNLFVAVIMDNFDYLTRDSSILGPHHLDEYIRVWAEYDPGAIGRIHHSEMYEMLRNMEPPVGFGKKCPYRLAYRKLIRMNMPVDENGTVNFTTTLFALIRESLNIKMSTAEYMDIKDMELRQTICKMWPVQAKKKLNLIVPPDSELVFHKMTVGKIYAGYLIVENWRAYKNSQEQGPRSSPAVSIKSVTKPVVKEEKSANLLAKFFVAFKSNTNKSNISLDSHHE 5569 S +D S+ SMR LAKRT+++ PG+Q ++ K+LF+FSEEN IRKY+KIIIEWGPFEYMVLLTILANCIVL+ME HLP DKT L+ LE TE YFL IFCVEA LKIVALGF H+ AYLRN+WNI+DF+VVVTG L L ++ +RA+RVLRPLKLV GF SLQ+VLKSIIRAMAPLLQI LLVLFAITIFAIIGLEFYSG FH TCF S D LP +P +L PCS S N G+ GA+ CP+DY CK YWEGPNYGITSFDNIGYAMLTVFQCITMEGWT+IMY TNDA G+RFN+LYFVPLIILGSFFMLNLVLGVLSGEFAKERERVEKRRAFLKLRRQQQTEKEFNGYM+WIQ+AEEV+L E TTT+E+++RII+ARRRAEKQ+ K GK D +D E + E+K G +F SY + R+RKERC WRTEK R+++RR+VKSQPFYW VI+LVFFNTVC AIEH+ Q WL+ FL YAE+ FL LF++EM++KMYGL IR+YF+SSFNIFDC VI +FEII+G D+SFG+SVLRA+RLLRIFK+TRYWASLRNLVLSLLNSMRSIISLLFLLFLFILIFALLGMQLFGG+FNF+EG+P QNFD+FVKALLTVFQILTGEDWN+VMYNGI+++GGV G ++S+YFVL+++FGNYTLLNVFLAIAVDNLANAQELT AEE+ A ++AA+ A + + + P P S + N + + + D Q L N N P GK+ + NFNS+ESD +Q KPVLPYS+MFIF+P N++RRFCHFVVNLRYFDLFIMIVICASSIALAAEDPV E + +N ILE FDYAFTGVFTVE++LK+IDLG++LHPGSY RD WNILDA VV ALVAF++ + + G +SAKNLNTIKSLRVLRVLRPLKTINRVPKLKAVFDCVVSSLKNV +I IVY LFQFIFAVIAVQLFQGKFFYCND SK +RE C+GYFF++ R P + R W DF++DN++ AMLTLFTVT+GEGWP VLK+S++ST +D GP D+RQEMAI+Y+VFFIVFPFFFVNIFVALIIITFQ+QGENELI+L++DKNQK+CIDFAIN +PLCRYMPKD+ ++KYRVWRLVVSTPFEY+IMVMIA+NTLILMMKY+R+E+K+ + D +QQAY +YCNTL++ NSAFTVMFSIEC+LKIMAFGPKNYFRD WNIFDFITVIGSITDVLVSELQ+S+FLSLGFLRLFRAARLIKLLRQGY+IRI+ WTFIQS KALPYVCLLIAMLFFIY IIGMQVFGNI+ Q+N HNNF++F++GLLLLFRCATGE+WQEIML C + CE + CGS FTY YF++F FLCSFLMLNLFVAVIMDNFDYLTRDSSILGPHHLDE++RVWAEYDP A G IHH EMYEMLRNMEPPVGFGK CP RLAYRKL+RMNMPVDENG V+FTTTLFALIRESL IK E+MD +D ELR+TICKMWPV+ +K L++++PPDSELV+HKMTVGKIYA +LI+ENWR + Q +G + KSA++LA+FF A K N +KS D E Sbjct: 98 SPNDTSRENSMRILAKRTLHIDLPGLQPASQKALFLFSEENAIRKYSKIIIEWGPFEYMVLLTILANCIVLAMEEHLPSHDKTTLSETLEQTETYFLIIFCVEASLKIVALGFLFHRGAYLRNIWNIVDFIVVVTGLLAYIL--------PNLNQPAVRALRVLRPLKLVTGFESLQIVLKSIIRAMAPLLQISLLVLFAITIFAIIGLEFYSGGFHMTCFSVYSPDTLPTSLPNRPNLAPCSLPNGTSTNSGGIPQGAFVCPQDYICKGYWEGPNYGITSFDNIGYAMLTVFQCITMEGWTEIMYSTNDAFGDRFNYLYFVPLIILGSFFMLNLVLGVLSGEFAKERERVEKRRAFLKLRRQQQTEKEFNGYMDWIQRAEEVILAEDTTTAEERLRIISARRRAEKQRLKQHGKESGQTDMAPDDVEFFEESK---GYLFGHSYTDLVRKRKERCQGCWRTEKRIRYAIRRMVKSQPFYWFVIMLVFFNTVCGAIEHHGQPPWLSSFLYYAEFFFLGLFIIEMLLKMYGLKIRIYFESSFNIFDCAVIVVGIFEIIWGFVHPDASFGISVLRAVRLLRIFKITRYWASLRNLVLSLLNSMRSIISLLFLLFLFILIFALLGMQLFGGDFNFDEGRPTQNFDSFVKALLTVFQILTGEDWNSVMYNGIRAQGGVTSGGAIYSVYFVLVMLFGNYTLLNVFLAIAVDNLANAQELTEAEEKLAKCREQAAEEALAAETNTGENGEVNEVSQPRCTLPQNSNSQTHSNTSQNRICTSPLAEDEKQTNGQLDMSLANQNGLPMGKMPLNHVGMMNFNSMESDDTARLHGSGVQVQGKPVLPYSSMFIFAPTNAIRRFCHFVVNLRYFDLFIMIVICASSIALAAEDPVSENARRNTILEHFDYAFTGVFTVELVLKVIDLGVVLHPGSYFRDAWNILDAIVVFFALVAFVV-RSATSLGRIGSNTSAKNLNTIKSLRVLRVLRPLKTINRVPKLKAVFDCVVSSLKNVSSIFIVYWLFQFIFAVIAVQLFQGKFFYCNDVSKMTREECQGYFFEFNDRGEPFVQNRTWNMWDFNYDNVVNAMLTLFTVTSGEGWPAVLKHSIDSTMVDRGPATDFRQEMAIYYVVFFIVFPFFFVNIFVALIIITFQKQGENELIELEIDKNQKRCIDFAINARPLCRYMPKDRQSLKYRVWRLVVSTPFEYYIMVMIAINTLILMMKYHRQEQKSFMTVSVDTDQQAYHSYCNTLLYFNSAFTVMFSIECMLKIMAFGPKNYFRDRWNIFDFITVIGSITDVLVSELQESAFLSLGFLRLFRAARLIKLLRQGYSIRIIFWTFIQSIKALPYVCLLIAMLFFIYCIIGMQVFGNIRTDPLSQLNNHNNFKSFSDGLLLLFRCATGENWQEIMLDCTAGRECESAGDT-----CGSTFTYPYFITFYFLCSFLMLNLFVAVIMDNFDYLTRDSSILGPHHLDEFVRVWAEYDPEAKGLIHHKEMYEMLRNMEPPVGFGKNCPCRLAYRKLVRMNMPVDENGCVHFTTTLFALIRESLGIKTGPTEFMDQRDNELRETICKMWPVRGRKMLHILIPPDSELVYHKMTVGKIYASFLIIENWRTTRAFQGKGGTA-----------------KSASILARFFGAVKKNVHKSTPGSDEEEE 1729
BLAST of Voltage dependent L type calcium channel subunit vs. TrEMBL
Match: A0A0X3PSD7 (Ca_chan_IQ domain-containing protein OS=Schistocephalus solidus OX=70667 GN=TR117297 PE=3 SV=1) HSP 1 Score: 2053.48 bits (5319), Expect = 0.000e+0 Identity = 1161/1706 (68.05%), Postives = 1328/1706 (77.84%), Query Frame = 2 Query: 689 STSKSLFIFSEENVIRKYAKIIIEWGPFEYMVLLTILANCIVLSMERHLPKKDKTLLAGQLELTEKYFLGIFCVEALLKIVALGFCCHKEAYLRNVWNIMDFVVVVTGFLMMFLNIDNHSDSSTVDLRTLRAVRVLRPLKLVAGFPSLQVVLKSIIRAMAPLLQIGLLVLFAITIFAIIGLEFYSGAFHYTCF-KANSDKLPLPIPTEKSLVPCSNSKNGS--------GLGAYTCPEDYQCKAYWEGPNYGITSFDNIGYAMLTVFQCITMEGWTDIMYHTNDAIGNRFNWLYFVPLIILGSFFMLNLVLGVLSGXXXXXXXXXXXXXXXLKLRRQQQTEKEFNGYMEWIQKAEEVLLNEATTTSEDKMRIIAARRRAEKQKYKLLGKNQSIPDFEYEDTELYSETKSMKGNIFIRSYAGIRRRRKERCTSFWRTEKHFRFSVRRLVKSQPFYWAVIILVFFNTVCVAIEHYEQGKWLTLFLNYAEYVFLCLFMMEMMIKMYGLSIRVYFQSSFNIFDCVVIAGSLFEIIYGIFVQDSSFGLSVLRALRLLRIFKVTRYWAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXGMQLFGGEFNFEEGKPPQNFDTFVKALLTVFQILTGEDWNTVMYNGIQSKGGVKERGTVFSIYFVLLVVFGNYTLLNVFLAIAVDNLANXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSSDNFIGRLPLSIDPPMVQVCP-PSPQTANSLISKNFSFDHNQVEVNDKGCLLNTNKPNGKL-GMLGHDN--------TNFNSLESDPVPNKIEPETI-QRKPVLPYSAMFIFSPLNSLRRFCHFVVNLRYFDLFIMIVICASSIALAAEDPVKEKSLKNNILEFFDYAFTGVFTVEMILKIIDLGIILHPGSYCRDLWNILDATVVICALVAFIMGQKPSPTGNKLRGSSAKNLNTIKSLRVLRVLRPLKTINRVPKLKAVFDCVVSSLKNVFNILIVYILFQFIFAVIAVQLFQGKFFYCNDASKSSRETCRGYFFDYAGRSTPETKKRLWQHHDFHFDNILYAMLTLFTVTTGEGWPTVLKNSMESTNIDNGPIADYRQEMAXXXXXXXXXXXXXXXXXXXALIIITFQEQGENELIDLDLDKNQKQCIDFAINEKPLCRYMPKDKTTIKYRVWRLVVSTPFEYFIMVMIALNTLILMMKYYREEKKASSAATHDREQQAYLNYCNTLIFLNSAFTVMFSIECVLKIMAFGPKNYFRDPWNIFDFITVIGSITDVLVSELQDXXXXXXXXXXXXXXXXXXXXXXQGYTIRILLWTFIQSFKALPYVCLLIAMLFFIYSIIGMQVFGNIKLISEYQINRHNNFQTFTNGLLLLFRCATGESWQEIMLACDNNKPCEKDIENTNNFDCGSNFTYIYFVSFIFLCSFLMLNLFVAVIMDNFDYLTRDSSILGPHHLDEYIRVWAEYDPGAIGRIHHSEMYEMLRNMEPPVGFGKKCPYRLAYRKLIRMNMPVDENGTVNFTTTLFALIRESLNIKMSTAEYMDIKDMELRQTICKMWPVQAKKKLNLIVPPDSELVFHKMTVGKIYAGYLIVENWRAYKNSQEQGPRSSPAVSIKSVTKPVVKEEKSANLLAKFFVAFKSNTNKSNISLDSHHE-----------------RDEERFSIDHTYGEDYDANRRYSYL--RRGSKPRGSKEIYSD 5689 + +K LFIFSEEN+IRK A+III+WGPFEYMVLLTI ANCIVL+MERH P DK+ L LE +EKYFLGIFCVEALLKI ALGF ++ AYLR++WNI+DF+VVVTG L L ++ LRA+RVLRPLKLV GF SLQ+VLKSIIRAMAPLLQIGLL+LFAITIFAIIGLEFYSG FH TCF + N + LP IP +SLVPC N NGS GA+ CP Y CK YWEGPNYGITSFDNIGYAMLTVFQCITMEGWTDIMY T+DAIG+RFN LYFVPLI+LGSFFMLNL+LGVLSGEFAKE+ERVEKRRAFLKLRRQQQTEKEF+GYM+WIQ AEEV+L E TT++ED++RII+ARRRA+K++ K Q++PD +DTELYS+T+ GN+F Y + R K R S +R EK R+++RR+ KSQP YW VIILVF NT+CVAIEH Q WLT FL YAEYVFL LFM EM++KMYGL R+YFQSSFNIFDCVVI GSLFEII+ D+SFG+SVLRALRLLRIFK+TRYWA LRNLVLSLLNSMRSI+SLLFLLFLFILIFALLGMQLFGGEFNF EG PPQNFDTF+KALLTVFQILTGEDWN++MYNGI+S+GG GT++ IYFVLLV+FGNYTLLNVFLAIAVDNLANAQ+L+ AE E+ E + + + D + + I ++ P + A +L + + H+ V D G T + N KL G N F S+ESD + + ET Q KPVLPYS+MFIF+P N +RRFCHFVVNLRYFDLFIMIVICASSIALA EDPV E S +N ILE FDYAFTGVFTVEM+LKIIDLG++ HPG+YCRD WNILDA VV+CALVAF M + G +SAKNLNTIKSLRVLRVLRPLKTINRVPKLKAVFDCVVSSL+NVFNILIV+ LFQFIFAVIAVQL QGKFFYCNDASK S+E C+G FF+Y + P R W F++DN+ YAMLTLFTVTTGEGWPTVLKNSM++T ++ GPI DYRQEMAIFY+ FFIVFPFFFVNIFVALIIITFQ+QGENEL +L+LDKNQK+C+DFAIN PLCRYMPKD+ + KYRVWRLVVSTPFEY+IMVMIALNTLILMMKY+R+E+K S A T D QQ Y NYCNTLIFLNSAFTVMFS ECVLKIMAFGPKNYFRD WNIFDFITVIGSITDVLVSELQ S+FLSLGFLRLFRAARLIKLLRQGYTIRILLWTFIQS KALPYVCLLIAMLFFIY IIGMQVFGNIK Q+N HNNFQTF +GLLLLFRCATGE+WQE+ML CD + CE E+ CGS TY+YFV+FIFLCSFLMLNLFVAVIMDNFDYLTRDSSILGPHHLDEY+RVWAEYDP A G++HH++MYEMLRNMEPPVGFGKKCPYRLAYRKLIRMNMPVDENG V+FTTTLFALIRESL IK+ E MD +D ELR +C++WPVQAK+ LN++VPPDSEL ++KMTVGKIYAG L++EN R K Q Q SP S + EKSA+LLA+FF +++S + ++ + R EE + NR+ + L +RG KP+ + + D Sbjct: 74 TGNKLLFIFSEENIIRKCARIIIDWGPFEYMVLLTITANCIVLAMERHFPMNDKSRLTETLEQSEKYFLGIFCVEALLKITALGFVLNEGAYLRSIWNILDFIVVVTGLLAYIL--------PNLNQPALRALRVLRPLKLVTGFESLQIVLKSIIRAMAPLLQIGLLLLFAITIFAIIGLEFYSGGFHMTCFDERNPEVLPESIPNSRSLVPC-NVGNGSTTKASSTAAQGAFRCPPGYICKGYWEGPNYGITSFDNIGYAMLTVFQCITMEGWTDIMYTTDDAIGDRFNALYFVPLIVLGSFFMLNLILGVLSGEFAKEKERVEKRRAFLKLRRQQQTEKEFSGYMDWIQHAEEVILAEDTTSAEDRLRIISARRRAQKERRSRAAKGQAVPDLNMDDTELYSDTR---GNVF-NQYGFLLRPGKSRFESCFRYEKRVRYAIRRMAKSQPSYWCVIILVFLNTICVAIEHTGQPAWLTSFLYYAEYVFLGLFMTEMLLKMYGLGFRLYFQSSFNIFDCVVIIGSLFEIIWAYIHPDTSFGISVLRALRLLRIFKITRYWADLRNLVLSLLNSMRSILSLLFLLFLFILIFALLGMQLFGGEFNFIEGLPPQNFDTFIKALLTVFQILTGEDWNSIMYNGIRSQGGATSGGTIYCIYFVLLVLFGNYTLLNVFLAIAVDNLANAQDLSEAETEELKEGKEKKEDECSG----TEDAILAANQILIGTTKPRILPWVKDKDALNLPTDVNNILHDPRNVKDTG--EPTQQGNAKLNGKCITKNPFTTTGFGQQFVSVESDDTGHVTKTETKRQGKPVLPYSSMFIFAPNNGIRRFCHFVVNLRYFDLFIMIVICASSIALATEDPVAENSTRNKILEHFDYAFTGVFTVEMVLKIIDLGVVFHPGAYCRDPWNILDAIVVLCALVAFTMNRNAVRLGKPGTSASAKNLNTIKSLRVLRVLRPLKTINRVPKLKAVFDCVVSSLRNVFNILIVFCLFQFIFAVIAVQLLQGKFFYCNDASKLSKEECQGQFFEYNEQGVPTVVWRQWNSQGFNYDNVYYAMLTLFTVTTGEGWPTVLKNSMDATYVNQGPIEDYRQEMAIFYVTFFIVFPFFFVNIFVALIIITFQKQGENELFNLELDKNQKRCVDFAINAHPLCRYMPKDRRSWKYRVWRLVVSTPFEYYIMVMIALNTLILMMKYHRQERKTSMATTIDTAQQNYHNYCNTLIFLNSAFTVMFSFECVLKIMAFGPKNYFRDRWNIFDFITVIGSITDVLVSELQQSAFLSLGFLRLFRAARLIKLLRQGYTIRILLWTFIQSVKALPYVCLLIAMLFFIYCIIGMQVFGNIKNDPMTQMNIHNNFQTFASGLLLLFRCATGENWQEVMLDCDAGRECEGAGES-----CGSKMTYLYFVTFIFLCSFLMLNLFVAVIMDNFDYLTRDSSILGPHHLDEYVRVWAEYDPTARGKVHHTDMYEMLRNMEPPVGFGKKCPYRLAYRKLIRMNMPVDENGMVHFTTTLFALIRESLGIKIGPTEVMDQRDNELRYCLCRLWPVQAKRMLNILVPPDSELTYYKMTVGKIYAGLLMLENHRLEK--QPQCKDQSPDRRKLSSADTSPQSEKSADLLARFFGGVVHASHRSPRTSETEDDLNNVPRWRSPLKVISPSRQEEFGKFTKMAADKASDNRKLNDLLMKRGQKPKETANPHPD 1753
BLAST of Voltage dependent L type calcium channel subunit vs. TrEMBL
Match: A0A5K3F6C1 (Uncharacterized protein OS=Mesocestoides corti OX=53468 PE=4 SV=1) HSP 1 Score: 2049.25 bits (5308), Expect = 0.000e+0 Identity = 1147/1746 (65.69%), Postives = 1331/1746 (76.23%), Query Frame = 2 Query: 686 TSTSKSLFIFSEENVIRKYAKIIIEWGPFEYMVLLTILANCIVLSMERHLPKKDKTLLAGQLELTEKYFLGIFCVEALLKIVALGFCCHKEAYLRNVWNIMDFVVVVTGFLMMFLNIDNHSDSSTVDLRTLRAVRVLRPLKLVAGFPSLQVVLKSIIRAMAPLLQIGLLVLFAITIFAIIGLEFYSGAFHYTCF-KANSDKLPLPIPTEKSLVPC-----SNSKN--GSGLGAYTCPEDYQCKAYWEGPNYGITSFDNIGYAMLTVFQCITMEGWTDIMYHTNDAIGNRFNWLYFVPLIILGSFFMLNLVLGVLSGXXXXXXXXXXXXXXXLKLRRQQQTEKEFNGYMEWIQKAEEVLLNEATTTSEDKMRIIAARRRAEKQKYKLLGKNQSIPDFEYEDTELYSETKSMKGNIFIRSYAGIRRRRKERCTSFWRTEKHFRFSVRRLVKSQPFYWAVIILVFFNTVCVAIEHYEQGKWLTLFLNYAEYVFLCLFMMEMMIKMYGLSIRVYFQSSFNIFDCVVIAGSLFEIIYGIFVQDSSFGLSVLRALRLLRIFKVTRYWAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXGMQLFGGEFNFEEGKPPQNFDTFVKALLTVFQILTGEDWNTVMYNGIQSKGGVKERGTVFSIYFVLLVVFGNYTLLNVFLAIAVDNLANXXXXXXXXXXXXXXXXXXXXXXXX---XXXXXSSDNFIGRLPLSIDPPMVQVCPPSPQTANSLISKNFSFDHNQVEVNDKGCLLNTNKPNGKLGMLGHDN------TNFNSLESDPVPNKIEPETIQR-KPVLPYSAMFIFSPLNSLRRFCHFVVNLRYFDLFIMIVICASSIALAAEDPVKEKSLKNNILEFFDYAFTGVFTVEMILKIIDLGIILHPGSYCRDLWNILDATVVICALVAFIMGQKPSPTGNKLRGSSAKNLNTIKSLRVLRVLRPLKTINRVPKLKAVFDCVVSSLKNVFNILIVYILFQFIFAVIAVQLFQGKFFYCNDASKSSRETCRGYFFDYAGRSTPETKKRLWQHHDFHFDNILYAMLTLFTVTTGEGWPTVLKNSMESTNIDNGPIADYRQEMAXXXXXXXXXXXXXXXXXXXALIIITFQEQGENELIDLDLDKNQKQCIDFAINEKPLCRYMPKDKTTIKYRVWRLVVSTPFEYFIMVMIALNTLILMMKYYREEKKASSAATHDREQQAYLNYCNTLIFLNSAFTVMFSIECVLKIMAFGPKNYFRDPWNIFDFITVIGSITDVLVSELQDXXXXXXXXXXXXXXXXXXXXXXQGYTIRILLWTFIQSFKALPYVCLLIAMLFFIYSIIGMQVFGNIKLISEYQINRHNNFQTFTNGLLLLFRCATGESWQEIMLACDNNKPCEKDIENTNNFDCGSNFTYIYFVSFIFLCSFLMLNLFVAVIMDNFDYLTRDSSILGPHHLDEYIRVWAEYDPGAIGRIHHSEMYEMLRNMEPPVGFGKKCPYRLAYRKLIRMNMPVDENGTVNFTTTLFALIRESLNIKMSTAEYMDIKDMELRQTICKMWPVQAKKKLNLIVPPDSELVFHKMTVGKIYAGYLIVENWRAYKNSQEQGPRSSPAVSIKSVTKPVVKEEKSANLLAKFFVAFKSNTNKSNISLDSHHERDEERFSIDHTYGEDYDANRRYSYLRRGSKPRGSKEIYSDLTPTQDYSYGLRPEH--------ATIPGMPAPRKFG--NRPRSPMYSLSELETKDRANTP 5839 +S +K LFIFSEENVIRKYA+IIIEWGPFEYMVLLTI ANCIVL+MERH P DK+ L+ LE TEKYFLGIFCVEALLKI ALGF ++ AYLR++WNI+DF+VV TG L L ++ LRA+RVLRPLKLV GF SLQ+VLKSI RAMAPLLQIGLL+ FAITIFAI+GLEFYSG FH TCF + N D LP IP K+LVPC S+SK S G++ C Y CK YWEGPN+GITSFDNIGYAMLTVFQCITMEGWTDIMY T DA+G+RF+ YF PLI+LGSFFMLNL+LGVLSGEFAKE+ERVEKRRAFLKLRRQQQTEKEF GYM+WIQ AEEV+L E TT++ED++RIIAAR+RA+K+ K ++ D +ED +L+S+ K GN+F + + R+ R + WR E+ FR++VRRL KSQ YW+VI+LVF NT+CVAIEHY Q WLT FL YAEYVFL LFM EM++KMYGL R+YFQSSFNIFDCVVI GSLFEI+ + D+SFG+SVLRALRLLRIFKVTRYWA LRNLVLSLL+SMRSIISL+FLLFLFILIFALLGMQLFGGEFNFEEG PPQNFD+FVKALLTVFQILTGEDWN+VMYNGI+S+GG G ++ IYFVLLV+ GNYTLLNVFLAIAVDNLANA +L+ AE E Q A A N + S N + LP P CP F + + ++ L K NG + DN N S ESD + E KPVLPYS+MFIF+P N +RRFCHFVVNLRYFDLFIMIVICASSIALAAEDPV E S KN ILE FDYAFTGVFTVEM+LK+IDLG++LHPG+YCRD WNILDA VV CALVAF M + G +SAKNLNTIKSLRVLRVLRPLKTI RVPKLKAVFDCV+SSL+NV NILIV++LFQFIFAVIAVQLFQGKFFYCNDASK +R+ C+G FF+Y P T R W+ H F++DN+ YAMLTLFTVTTGEGWP VLKNSM++T+++ GP+ DY+Q+++IFYI FF+VFPFFFVNIFVALIIITFQ+QGENELIDL+LDKNQK+C+DFAIN PLCRYMPKDK + KYR+WRLVVSTPFEY+IMVMIALNTLILMMKY+R+E++ A D QQ Y NYCNTLIFLNSAFT+MFS+ECVLKIMAFGPKNYFRD WNIFDFITVIGSITDVLVSELQ S+FLSLGFLRLFRAARLIKLLRQGYT+RILLWTFIQS KALPYVCLLI +LFFIY IIGMQVFGNIK Q+N HNNFQTF +G+LLLFRCATGE+WQE+ML CD + CE + CGS TY+YFV+FIFL SFLMLNLFVAVIMDNFDYLTRDSSILGPHHLDE++RVWAEYDP A GRIHHS+MYEMLRNMEPPVGFGKKCPYRLAYRKLIRMNMPVD+NGTV+FTTTLFALIRESL IKM AE MD +D ELR ++ K+WPVQAK+ +N++VPPDSELV+HKMTVGKIYAG LI+EN+R K + + KSA+LLA+FF A N ++S + + E+ D T+ + + + ++RG K + ++ S T + + PEH A +P P + G ++P S + S+L + + P Sbjct: 79 SSGNKLLFIFSEENVIRKYARIIIEWGPFEYMVLLTITANCIVLAMERHYPSGDKSALSESLEQTEKYFLGIFCVEALLKIAALGFVLNEGAYLRSIWNIIDFLVVATGLLAYIL--------PNLNQPALRALRVLRPLKLVTGFESLQIVLKSIFRAMAPLLQIGLLLFFAITIFAIVGLEFYSGGFHMTCFDERNPDLLPDSIPNSKTLVPCNIGNESSSKGFFNSAHGSFRCDPGYICKGYWEGPNFGITSFDNIGYAMLTVFQCITMEGWTDIMYMTFDAVGDRFSAFYFGPLIVLGSFFMLNLILGVLSGEFAKEKERVEKRRAFLKLRRQQQTEKEFGGYMDWIQHAEEVILAEDTTSAEDRIRIIAARKRAQKEVSKKNARDSQGHDVNFEDADLFSDNK---GNVF-NQHGLLLRQGSGRFEACWRNERRFRYAVRRLAKSQLAYWSVIVLVFLNTICVAIEHYGQPAWLTSFLYYAEYVFLGLFMTEMLLKMYGLGFRLYFQSSFNIFDCVVIIGSLFEILLALVQPDTSFGISVLRALRLLRIFKVTRYWADLRNLVLSLLSSMRSIISLVFLLFLFILIFALLGMQLFGGEFNFEEGLPPQNFDSFVKALLTVFQILTGEDWNSVMYNGIRSQGGTNGGGFIYCIYFVLLVLIGNYTLLNVFLAIAVDNLANAHDLSDAEHADQKEEQSKAAKAQGLDPSNLDLSDPNAMHLLPWIRTPTKENSCP--------------CFSADPLNAVERTSQLGDPKANGNF-LSTPDNKQLRKTQNCISFESDETGQLQDSEAATHGKPVLPYSSMFIFAPTNGIRRFCHFVVNLRYFDLFIMIVICASSIALAAEDPVAENSTKNKILEHFDYAFTGVFTVEMVLKVIDLGVVLHPGAYCRDPWNILDAIVVFCALVAFTMNRNAVRLGKPATSASAKNLNTIKSLRVLRVLRPLKTIKRVPKLKAVFDCVISSLRNVLNILIVFVLFQFIFAVIAVQLFQGKFFYCNDASKLTRDECQGQFFEYNADGVPSTVWREWKSHGFNYDNVYYAMLTLFTVTTGEGWPGVLKNSMDATHVNQGPLEDYQQQVSIFYITFFVVFPFFFVNIFVALIIITFQKQGENELIDLELDKNQKRCVDFAINAHPLCRYMPKDKRSWKYRIWRLVVSTPFEYYIMVMIALNTLILMMKYHRQERRPLVATHIDTAQQNYHNYCNTLIFLNSAFTIMFSVECVLKIMAFGPKNYFRDRWNIFDFITVIGSITDVLVSELQQSAFLSLGFLRLFRAARLIKLLRQGYTVRILLWTFIQSVKALPYVCLLIVILFFIYCIIGMQVFGNIKNDPMTQMNNHNNFQTFGSGILLLFRCATGENWQEVMLDCDAGRECEG-----SGTSCGSKATYLYFVTFIFLSSFLMLNLFVAVIMDNFDYLTRDSSILGPHHLDEFVRVWAEYDPTARGRIHHSDMYEMLRNMEPPVGFGKKCPYRLAYRKLIRMNMPVDDNGTVHFTTTLFALIRESLGIKMGPAEIMDQRDNELRYSLLKLWPVQAKRMMNVLVPPDSELVYHKMTVGKIYAGLLILENYRLSKQPHSK------------------DQSKSADLLARFFGAVTHNVHRS-----ARNSETED----DSTHTGRWKSPTK-GLMKRGPKALSTAKVISMTTQPECTKPLVGPEHQKAAPTSAANEDKIPRPPEAGETDKPLSYATNPSDLSSIEEVQEP 1764 HSP 2 Score: 125.946 bits (315), Expect = 1.014e-24 Identity = 99/338 (29.29%), Postives = 150/338 (44.38%), Query Frame = 2 Query: 2936 NDKGCLLNTNKPNGKLGMLGHDNTNFNSLESDPVPNKIEPETIQRKPVLPYSAMFIFSPLNSLRRFCHFVVNLRYFDLFIMIVICASSIALAAED--PVKEKSLKNNILEFFDYAFTGVFTVEMILKIIDLGIILHPGSYCRDLWNILDATVVICALVAFIMGQKPSPTGNKLRGSSAKNLNTIKSLRVLRVLRPLKTINRVPKLKAVFDCVVSSLKNVFNILIVYILFQFIFAVIAVQLFQGKFFY-----------------------CNDASKSSRETCRGYFFDYAG--RSTPE-TKKRLWQHHDF---HFDNILYAMLTLFTVTTGEGWPTVL 3856 N LN P K H+N+ + E+DP I +FIFS N +R++ ++ F+ +++ I A+ I LA E P +KS + LE + F G+F VE +LKI LG +L+ G+Y R +WNI+D VV L+A+I+ NLN +LR LRVLRPLK + L+ V + ++ + I ++ IFA++ ++ + G F CN ++SS +G+F G R P K W+ +F FDNI YAMLT+F T EGW ++ Sbjct: 47 NASSTALNLQNPQQK-----HENS-LGAAENDPAAQPISSGN---------KLLFIFSEENVIRKYARIIIEWGPFEYMVLLTITANCIVLAMERHYPSGDKSALSESLEQTEKYFLGIFCVEALLKIAALGFVLNEGAYLRSIWNIIDFLVVATGLLAYIL----------------PNLNQ-PALRALRVLRPLKLVTGFESLQIVLKSIFRAMAPLLQIGLLLFFAITIFAIVGLEFYSGGFHMTCFDERNPDLLPDSIPNSKTLVPCNIGNESS---SKGFFNSAHGSFRCDPGYICKGYWEGPNFGITSFDNIGYAMLTVFQCITMEGWTDIM 349
BLAST of Voltage dependent L type calcium channel subunit vs. TrEMBL
Match: A0A0X3PE31 (Ca_chan_IQ domain-containing protein OS=Schistocephalus solidus OX=70667 GN=TR117297 PE=3 SV=1) HSP 1 Score: 2045.78 bits (5299), Expect = 0.000e+0 Identity = 1156/1706 (67.76%), Postives = 1324/1706 (77.61%), Query Frame = 2 Query: 689 STSKSLFIFSEENVIRKYAKIIIEWGPFEYMVLLTILANCIVLSMERHLPKKDKTLLAGQLELTEKYFLGIFCVEALLKIVALGFCCHKEAYLRNVWNIMDFVVVVTGFLMMFLNIDNHSDSSTVDLRTLRAVRVLRPLKLVAGFPSLQVVLKSIIRAMAPLLQIGLLVLFAITIFAIIGLEFYSGAFHYTCF-KANSDKLPLPIPTEKSLVPCSNSKNGS--------GLGAYTCPEDYQCKAYWEGPNYGITSFDNIGYAMLTVFQCITMEGWTDIMYHTNDAIGNRFNWLYFVPLIILGSFFMLNLVLGVLSGXXXXXXXXXXXXXXXLKLRRQQQTEKEFNGYMEWIQKAEEVLLNEATTTSEDKMRIIAARRRAEKQKYKLLGKNQSIPDFEYEDTELYSETKSMKGNIFIRSYAGIRRRRKERCTSFWRTEKHFRFSVRRLVKSQPFYWAVIILVFFNTVCVAIEHYEQGKWLTLFLNYAEYVFLCLFMMEMMIKMYGLSIRVYFQSSFNIFDCVVIAGSLFEIIYGIFVQDSSFGLSVLRALRLLRIFKVTRYWAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXGMQLFGGEFNFEEGKPPQNFDTFVKALLTVFQILTGEDWNTVMYNGIQSKGGVKERGTVFSIYFVLLVVFGNYTLLNVFLAIAVDNLANXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSSDNFIGRLPLSIDPPMVQVCP-PSPQTANSLISKNFSFDHNQVEVNDKGCLLNTNKPNGKL-GMLGHDN--------TNFNSLESDPVPNKIEPETI-QRKPVLPYSAMFIFSPLNSLRRFCHFVVNLRYFDLFIMIVICASSIALAAEDPVKEKSLKNNILEFFDYAFTGVFTVEMILKIIDLGIILHPGSYCRDLWNILDATVVICALVAFIMGQKPSPTGNKLRGSSAKNLNTIKSLRVLRVLRPLKTINRVPKLKAVFDCVVSSLKNVFNILIVYILFQFIFAVIAVQLFQGKFFYCNDASKSSRETCRGYFFDYAGRSTPETKKRLWQHHDFHFDNILYAMLTLFTVTTGEGWPTVLKNSMESTNIDNGPIADYRQEMAXXXXXXXXXXXXXXXXXXXALIIITFQEQGENELIDLDLDKNQKQCIDFAINEKPLCRYMPKDKTTIKYRVWRLVVSTPFEYFIMVMIALNTLILMMKYYREEKKASSAATHDREQQAYLNYCNTLIFLNSAFTVMFSIECVLKIMAFGPKNYFRDPWNIFDFITVIGSITDVLVSELQDXXXXXXXXXXXXXXXXXXXXXXQGYTIRILLWTFIQSFKALPYVCLLIAMLFFIYSIIGMQVFGNIKLISEYQINRHNNFQTFTNGLLLLFRCATGESWQEIMLACDNNKPCEKDIENTNNFDCGSNFTYIYFVSFIFLCSFLMLNLFVAVIMDNFDYLTRDSSILGPHHLDEYIRVWAEYDPGAIGRIHHSEMYEMLRNMEPPVGFGKKCPYRLAYRKLIRMNMPVDENGTVNFTTTLFALIRESLNIKMSTAEYMDIKDMELRQTICKMWPVQAKKKLNLIVPPDSELVFHKMTVGKIYAGYLIVENWRAYKNSQEQGPRSSPAVSIKSVTKPVVKEEKSANLLAKFFVAFKSNTNKSNISLDSHHE-----------------RDEERFSIDHTYGEDYDANRRYSYL--RRGSKPRGSKEIYSD 5689 + +K LFIFSEEN+IRK A+III+WGPFEYMVLLTI ANCIVL+MERH P DK+ L LE +EKYFLGIFCVEALLKI ALGF ++ AYLR++WNI+DF+VVVTG L L ++ LRA+RVLRPLKLV GF SLQ+VLKSIIRAMAPLLQIGLL+LFAITIFAIIGLEFYSG FH TCF + N + LP IP +SLVPC N NGS GA+ CP Y CK YWEGPNYGITSFDNIGYAMLTVFQCITMEGWTDIMY T+DAIG+RFN LYFVPLI+LGSFFMLNL+LGVLSGEFAKE+ERVEKRRAFLKLRRQQQTEKEF+GYM+WIQ AEEV+L E TT++ED++RII+ARRRA+K++ K Q++PD +DTELYS+T+ GN+F Y + R K R S +R EK R+++RR+ KSQP YW VIILVF NT+CVAIEH Q WLT FL YAEYVFL LFM EM++KMYGL R+YFQSSFNIFDCVVI GSLFEII+ D+SFG+SVLRALRLLRIFK+TRYWA LRNLVLSLLNSMRSI+SLLFLLFLFILIFALLGMQLFGGEFNF EG PPQNFDTF+KALLTVFQILTGEDWN++MYNGI+S+GG GT++ IYFVLLV+FGNYTLLNVFLAIAVDNLANAQ+L+ AE E+ E + + + D + + I ++ P + A +L + + H+ V D G T + N KL G N F S+ESD + + ET Q KPVLPYS+MFIF+P N +RRFCHFVVNLRYFDLFIMIVICASSIALA EDPV E S +N ILE FDYAFTGVFTVEM+LKIIDLG++ HPG+YCRD WNILDA VV+CALVAF M + G +SAKNLNTIKSLRVLRVLRPLKTINRVPKLKAVFDCVVSSL+NVFNILIV+ LFQFIFAVIAVQL QGKFFYCNDASK S+E C+G FF+Y + P R W F++DN+ YAMLTLFTVTTGEGWPTVLKNSM++T ++ GPI DYRQEMAIFY+ FFIVFPFFFVNIFVALIIITFQ+QGENEL +L+LDKNQK+C+DFAIN PLCRYMPKD+ + KYRVWRLVVSTPFEY+IMVMIALNTLILMMKY+R+E+K S A T D QQ Y NYCNTLIFLNSAFTVMFS ECVLKIMAFGPKNYFRD WNIFDFITVIGSITDVLVSELQ S+FLSLGFLRLFRAARLIKLLRQGYTIRILLWTFIQS KALPYVCLLIAMLFFIY IIGMQVFGNIK Q+N HNNFQTF +GLLLLFRCATGE+WQE+ML CD + CE E+ CGS TY+YFV+FIFLCSFLMLNLFVAVIMDNFDYLTRDSSILGPHHLDEY+RVWAEYDP A G++HH++MYEMLRNMEPPVGFGKKCPYRLAYRKLIRMNMPVDENG V+FTTTLFALIRESL IK+ E MD +D ELR +C++WPVQAK+ LN++VPPDSEL ++KMTVGKIYAG L++EN R K Q + + KSA+LLA+FF +++S + ++ + R EE + NR+ + L +RG KP+ + + D Sbjct: 74 TGNKLLFIFSEENIIRKCARIIIDWGPFEYMVLLTITANCIVLAMERHFPMNDKSRLTETLEQSEKYFLGIFCVEALLKITALGFVLNEGAYLRSIWNILDFIVVVTGLLAYIL--------PNLNQPALRALRVLRPLKLVTGFESLQIVLKSIIRAMAPLLQIGLLLLFAITIFAIIGLEFYSGGFHMTCFDERNPEVLPESIPNSRSLVPC-NVGNGSTTKASSTAAQGAFRCPPGYICKGYWEGPNYGITSFDNIGYAMLTVFQCITMEGWTDIMYTTDDAIGDRFNALYFVPLIVLGSFFMLNLILGVLSGEFAKEKERVEKRRAFLKLRRQQQTEKEFSGYMDWIQHAEEVILAEDTTSAEDRLRIISARRRAQKERRSRAAKGQAVPDLNMDDTELYSDTR---GNVF-NQYGFLLRPGKSRFESCFRYEKRVRYAIRRMAKSQPSYWCVIILVFLNTICVAIEHTGQPAWLTSFLYYAEYVFLGLFMTEMLLKMYGLGFRLYFQSSFNIFDCVVIIGSLFEIIWAYIHPDTSFGISVLRALRLLRIFKITRYWADLRNLVLSLLNSMRSILSLLFLLFLFILIFALLGMQLFGGEFNFIEGLPPQNFDTFIKALLTVFQILTGEDWNSIMYNGIRSQGGATSGGTIYCIYFVLLVLFGNYTLLNVFLAIAVDNLANAQDLSEAETEELKEGKEKKEDECSG----TEDAILAANQILIGTTKPRILPWVKDKDALNLPTDVNNILHDPRNVKDTG--EPTQQGNAKLNGKCITKNPFTTTGFGQQFVSVESDDTGHVTKTETKRQGKPVLPYSSMFIFAPNNGIRRFCHFVVNLRYFDLFIMIVICASSIALATEDPVAENSTRNKILEHFDYAFTGVFTVEMVLKIIDLGVVFHPGAYCRDPWNILDAIVVLCALVAFTMNRNAVRLGKPGTSASAKNLNTIKSLRVLRVLRPLKTINRVPKLKAVFDCVVSSLRNVFNILIVFCLFQFIFAVIAVQLLQGKFFYCNDASKLSKEECQGQFFEYNEQGVPTVVWRQWNSQGFNYDNVYYAMLTLFTVTTGEGWPTVLKNSMDATYVNQGPIEDYRQEMAIFYVTFFIVFPFFFVNIFVALIIITFQKQGENELFNLELDKNQKRCVDFAINAHPLCRYMPKDRRSWKYRVWRLVVSTPFEYYIMVMIALNTLILMMKYHRQERKTSMATTIDTAQQNYHNYCNTLIFLNSAFTVMFSFECVLKIMAFGPKNYFRDRWNIFDFITVIGSITDVLVSELQQSAFLSLGFLRLFRAARLIKLLRQGYTIRILLWTFIQSVKALPYVCLLIAMLFFIYCIIGMQVFGNIKNDPMTQMNIHNNFQTFASGLLLLFRCATGENWQEVMLDCDAGRECEGAGES-----CGSKMTYLYFVTFIFLCSFLMLNLFVAVIMDNFDYLTRDSSILGPHHLDEYVRVWAEYDPTARGKVHHTDMYEMLRNMEPPVGFGKKCPYRLAYRKLIRMNMPVDENGMVHFTTTLFALIRESLGIKIGPTEVMDQRDNELRYCLCRLWPVQAKRMLNILVPPDSELTYYKMTVGKIYAGLLMLENHRLEKQPQCK------------------DQSKSADLLARFFGGVVHASHRSPRTSETEDDLNNVPRWRSPLKVISPSRQEEFGKFTKMAADKASDNRKLNDLLMKRGQKPKETANPHPD 1737
BLAST of Voltage dependent L type calcium channel subunit vs. Ensembl Cavefish
Match: cacna1sa (calcium channel, voltage-dependent, L type, alpha 1S subunit, a [Source:ZFIN;Acc:ZDB-GENE-090514-1]) HSP 1 Score: 1057.36 bits (2733), Expect = 0.000e+0 Identity = 683/1636 (41.75%), Postives = 961/1636 (58.74%), Query Frame = 2 Query: 623 KTTSMRSLAKRTINLSFPGMQTSTSKSLFIFSEENVIRKYAKIIIEWGPFEYMVLLTILANCIVLSMERHLPKKDKTLLAGQLELTEKYFLGIFCVEALLKIVALGFCCHKEAYLRNVWNIMDFVVVVTGFLMMFLNIDNH---------SDSSTVDLRTLRAVRVLRPLKLVAGFPSLQVVLKSIIRAMAPLLQIGLLVLFAITIFAIIGLEFYSGAFHYTCFKANSDKLPLPIPTEKSLVPCSNSKNGSGLGAYTCPEDYQCKAYWEGPNYGITSFDNIGYAMLTVFQCITMEGWTDIMYHTNDAIGNRFNWLYFVPLIILGSFFMLNLVLGVLSGXXXXXXXXXXXXXXXLKLRRQQQTEKEFNGYMEWIQKAEEVLLNEATTTSEDKMRIIAARRRAEKQKYKLLGKNQSIPDFEYEDTELYSETKSMKGNIFIRSYAGIRRRRKERCTSFWRTEKHFRFSVRRLVKSQPFYWAVIILVFFNTVCVAIEHYEQGKWLTLFLNYAEYVFLCLFMMEMMIKMYGLSIRVYFQSSFNIFDCVVIAGSLFEIIYGIFVQDSSFGLSVLRALRLLRIFKVTRYWAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXGMQLFGGEFNFEEGKPPQ-NFDTFVKALLTVFQILTGEDWNTVMYNGIQSKGGVKERGTVFSIYFVLLVVFGNYTLLNVFLAIAVDNLANXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSSDNFIGRLPLSIDPPMVQVCPPSPQTANSLISKNFSFDHNQVEVNDKGCLLNTNKPNGKLGMLGHDNTNFNSLESDPVPNKIEPETIQRK--PVLPYSAMFIFSPLNSLRRFCHFVVNLRYFDLFIMIVICASSIALAAEDPVKEKSLKNNILEFFDYAFTGVFTVEMILKIIDLGIILHPGSYCRDLWNILDATVVICALVAFIMGQKPSPTGNKLRGSSAKNLNTIKSLRVLRVLRPLKTINRVPKLKAVFDCVVSSLKNVFNILIVYILFQFIFAVIAVQLFQGKFFYCNDASKSSRETCRGYFFDYAGRSTP--ETKKRLWQHHDFHFDNILYAMLTLFTVTTGEGWPTVLKNSMESTNIDNGPIADYRQEMAXXXXXXXXXXXXXXXXXXXALIIITFQEQGENELIDLDLDKNQKQCIDFAINEKPLCRYMPKDKTTIKYRVWRLVVSTPFEYFIMVMIALNTLILMMKYYREEKKASSAATHDREQQAYLNYCNTLIFLNSAFTVMFSIECVLKIMAFGPKNYFRDPWNIFDFITVIGSITDVLVSEL--------------QDXXXXXXXXXXXXXXXXXXXXXXQGYTIRILLWTFIQSFKALPYVCLLIAMLFFIYSIIGMQVFGNIKLISEYQINRHNNFQTFTNGLLLLFRCATGESWQEIMLACDNNKPCE--KDIENTNNFDCGSNFTYIYFVSFIFLCSFLMLNLFVAVIMDNFDYLTRDSSILGPHHLDEYIRVWAEYDPGAIGRIHHSEMYEMLRNMEPPVGFGKKCPYRLAYRKLIRMNMPVDENGTVNFTTTLFALIRESLNIKMSTAEYMDIKDMELRQTICKMWPVQAKKKLNLIVPPDSELVFHKMTVGKIYAGYLIVENWRAYKNSQEQGPRSSPA 5440 + T R ++ L G ++SL + +N RK I+EW PFE ++L+TI ANC+ L++ +P++D LE E FL IF +E LKIVA G H +AYLRN WNI+DFV+V G + ++ N+ D++ LRA RVLRPL+LV+G PSLQVV+ SI+++M PL I LLV F +TI+AIIGLE + H TC+ + +D + + EK+ PC+ + NG CK W GPN GIT FDN+G++MLTV+QCIT +GWTD++Y NDAIG + WLYFV LI+LGSFF+LN+VLGVL G F KERE+ + + KLR +QQ +++ GYM+WI +A EV+ N+ +D+ ++ + DTE E + + R +R R R + FR R VKS+ FYW V +LVFFNT+ +A EH+ Q + LT F + LC+F +EM++KMY L + YF S FN FDC V++ + E+I S+ G+SV+R +RLLR+ KVT+YW SL NLV SLLNS+RSI SLL LLFLFI+IFALLGMQ+FGG+FNF + + + NFD F +AL+TVFQILTGEDWN+VMY+GI + GG G + SIYF++L V GNY LLNVFLAIAVDNLA A+ LT+A++EKA E +R A +++ D L+ + P + + K F+ N E+ D P G D + + P P + ++ P+ S+ FIF P N R+ CH ++N F I++ I SSI+LAAEDP+ S +N +L + D FT VFT E++LK+ G LH GS+CR+ +NILD VV +L++ G + ++ +K LRVLRVLRPL+ INR LK V CV ++K + NI++V +L F+FA I VQLF+GKFF+C D K + E CRG + Y + E ++R W + F+FDNIL ML LFTV+T EGWP +L +++S + + GP+ + R E++IF+IV+ I+ FF +NIFV +I+TFQEQGE E + +LDKNQ+QC+ +A+ +PL Y+PK+ +Y+VW +V S FEY + ++I LNT+ L M++ + S TH + LN FTV+F++E LK+ AF K YF DPWN+FDF+ V+GSI DV++SE+ ++ +S+ RLFR RL+KLL + IR LLWTFI+SF+ALPYV LLI MLFFIY++IGMQVFG I LI INR+NNFQTF +L+LFRCATGE WQE+M C + C+ D + CG+ F +YF+SF L F+ ++ + + S+ H ++ + GRI H ++ +LR ++PP+GFGK CP+R+A ++LI MNMP++ +GTV F TLFAL+R +L IK T + ELR I K+W + K L+ ++PP + ++TVGK YA +LI E++R + QE+ PA Sbjct: 16 EETLKRKQREKLKKLQATGGNPRPARSLLFLTLKNPFRKACISIVEWKPFEIIILVTIFANCVALAVFMPMPEEDTNNTNSNLESLEYIFLIIFTLECFLKIVAYGLLFHADAYLRNCWNILDFVIVTMGLFTIAVDFINNISGVEAPVEQKGGGFDMKALRAFRVLRPLRLVSGVPSLQVVMSSILKSMLPLFHISLLVFFMVTIYAIIGLELFKCKMHKTCYYSGTDIVA-TVENEKA-SPCAEAGNGRRCTV----NGTVCKPGWPGPNDGITHFDNLGFSMLTVYQCITTQGWTDVLYWVNDAIGMEWPWLYFVTLILLGSFFILNMVLGVLCGSFTKEREKSSRSGEYQKLRERQQLDEDLKGYMDWITQA-EVMEND-----QDRQGLLPLQEGG-------------------SDTESLYELEGLN-----RLMYYVRHAR--------RWNRFFRRKCRVWVKSRLFYWLVFLLVFFNTLVIATEHHMQSQSLTNFQENSNTALLCMFAVEMVLKMYALGLPSYFMSLFNRFDCFVVSVGMLELILVHMGVMSAMGISVMRCIRLLRLIKVTKYWTSLSNLVASLLNSVRSIASLLLLLFLFIVIFALLGMQVFGGKFNFPDQEVRRSNFDNFPQALITVFQILTGEDWNSVMYDGIMAHGGPVIPGILVSIYFIILFVCGNYILLNVFLAIAVDNLAEAESLTSAQKEKAEEKKRKKLLRANLSDKGDEDKSTLAKKLAEQRAKTEGIPTTAKL------KVDEFESNVNEIKD---------PFPPADFPGDDEEEEPEIPTSPRPRPMADLQLKETVVPMPEASSFFIFGPQNKFRKLCHRIINATTFTNIILLFILLSSISLAAEDPIDPMSFRNQVLAYADIVFTSVFTAEIVLKMTTYGAFLHTGSFCRNSFNILDLIVVGVSLLSM--------------GMESSAISVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIKTIGNIVLVTMLLDFMFACIGVQLFKGKFFFCTDPLKMTEEECRGTYIHYQENALHEMEVRQREWMNSGFNFDNILNGMLALFTVSTFEGWPKLLYTAIDSNSENMGPVYNNRTEISIFFIVYLILIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVQYALKARPLRCYIPKNP--YQYQVWYIVTSCYFEYLMFLLIMLNTMCLGMQHCNQ----SEHVTHLSDM------------LNVIFTVLFTVEMFLKLGAFKAKGYFGDPWNVFDFVIVVGSIVDVILSEIDVSIEVNPMQAIADSENMSVSITLFRLFRVMRLVKLLNRFEGIRNLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALIDGTVINRNNNFQTFPQAVLVLFRCATGEGWQEVMQGCLYGQRCDPKSDYLPGEEYTCGAGFAVLYFMSFYML-------FFIYAVIGIYIF-----SVFALFHFMHFMNC---MNAPCRGRIKHLDVVTLLRRIQPPLGFGKFCPHRVACKRLISMNMPLNSDGTVTFNATLFALVRTALRIK--TEGNFQQANEELRAIIKKIWKRTSMKLLDQVIPPIGD---DEVTVGKFYATFLIQEHFRKFMKRQEEYYGYRPA 1540
BLAST of Voltage dependent L type calcium channel subunit vs. Ensembl Cavefish
Match: cacna1sa (calcium channel, voltage-dependent, L type, alpha 1S subunit, a [Source:ZFIN;Acc:ZDB-GENE-090514-1]) HSP 1 Score: 1056.97 bits (2732), Expect = 0.000e+0 Identity = 686/1638 (41.88%), Postives = 966/1638 (58.97%), Query Frame = 2 Query: 623 KTTSMRSLAKRTINLSFPGMQTSTSKSLFIFSEENVIRKYAKIIIEWGPFEYMVLLTILANCIVLSMERHLPKKDKTLLAGQLELTEKYFLGIFCVEALLKIVALGFCCHKEAYLRNVWNIMDFVVVVTGFLMMFLNIDNH---------SDSSTVDLRTLRAVRVLRPLKLVAGFPSLQVVLKSIIRAMAPLLQIGLLVLFAITIFAIIGLEFYSGAFHYTCFKANSDKLPLPIPTEKSLVPCSNSKNGSGLGAYTCPEDYQCKAYWEGPNYGITSFDNIGYAMLTVFQCITMEGWTDIMYHTNDAIGNRFNWLYFVPLIILGSFFMLNLVLGVLSGXXXXXXXXXXXXXXXLKLRRQQQTEKEFNGYMEWIQKAEEVLLNEATTTSEDKMRIIAARRRAEKQKYKLLGKNQSIPDFEYEDTELYSETKSMKGNIFIRSYAGIRRRRKERCTSFWRTEKHFRFSVRRLVKSQPFYWAVIILVFFNTVCVAIEHYEQGKWLTLFLNYAEYVFLCLFMMEMMIKMYGLSIRVYFQSSFNIFDCVVIAGSLFEIIYGIFVQDSSFGLSVLRALRLLRIFKVTRYWAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXGMQLFGGEFNFEEGKPPQ-NFDTFVKALLTVFQILTGEDWNTVMYNGIQSKGGVKERGTVFSIYFVLLVVFGNYTLLNVFLAIAVDNLANXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSSDNFIGRLPLSIDPPMVQVCPPSPQTANSLISKNFSFDHNQVEVNDKGCLLNTNKPNGKLGMLGHDNTNFNSLESDPVPNKIEPETIQRK--PVLPYSAMFIFSPLNSLRRFCHFVVNLRYFDLFIMIVICASSIALAAEDPVKEKSLKNNILEFFDYAFTGVFTVEMILKIIDLGIILHPGSYCRDLWNILDATVVICALVAFIMGQKPSPTGNKLRGSSAKNLNTIKSLRVLRVLRPLKTINRVPKLKAVFDCVVSSLKNVFNILIVYILFQFIFAVIAVQLFQGKFFYCNDASKSSRETCRGYFFDYAGRSTP--ETKKRLWQHHDFHFDNILYAMLTLFTVTTGEGWPTVLKNSMESTNIDNGPIADYRQEMAXXXXXXXXXXXXXXXXXXXALIIITFQEQGENELIDLDLDKNQKQCIDFAINEKPLCRYMPKDKTTIKYRVWRLVVSTPFEYFIMVMIALNTLILMMKYYREEKKASSAATHDREQQAYLNYCNTLIFLNSAFTVMFSIECVLKIMAFGPKNYFRDPWNIFDFITVIGSITDVLVSELQDXXXX---------------XXXXXXXXXXXXXXXXXXQGYTIRILLWTFIQSFKALPYVCLLIAMLFFIYSIIGMQVFGNIKLISEYQINRHNNFQTFTNGLLLLFRCATGESWQEIMLACDNNKPCE--KDIENTNNFDCGSNFTYIYFVSFIFL-CSFLMLNLFVAVIMDNFDYLTRDSSILGPHHLDEYIRVWAEYDPGAIGRIHHSEMYEMLRNMEPPVGFGKKCPYRLAYRKLIRMNMPVDENGTVNFTTTLFALIRESLNIKMSTAEYMDIKDMELRQTICKMWPVQAKKKLNLIVPPDSELVFHKMTVGKIYAGYLIVENWRAYKNSQEQGPRSSPA 5440 + T R ++ L G ++SL + +N RK I+EW PFE ++L+TI ANC+ L++ +P++D LE E FL IF +E LKIVA G H +AYLRN WNI+DFV+V G + ++ N+ D++ LRA RVLRPL+LV+G PSLQVV+ SI+++M PL I LLV F +TI+AIIGLE + H TC+ + +D + + EK+ PC+ + NG CK W GPN GIT FDN+G++MLTV+QCIT +GWTD++Y NDAIG + WLYFV LI+LGSFF+LN+VLGVL G F KERE+ + + KLR +QQ +++ GYM+WI +A EV+ N+ +D+ ++ + DTE E + + R +R R R + FR R VKS+ FYW V +LVFFNT+ +A EH+ Q + LT F + LC+F +EM++KMY L + YF S FN FDC V++ + E+I S+ G+SV+R +RLLR+ KVT+YW SL NLV SLLNS+RSI SLL LLFLFI+IFALLGMQ+FGG+FNF + + + NFD F +AL+TVFQILTGEDWN+VMY+GI + GG G + SIYF++L V GNY LLNVFLAIAVDNLA A+ LT+A++EKA E +R A +++ D L+ + P + + K F+ N E+ D P G D + + P P + ++ P+ S+ FIF P N R+ CH ++N F I++ I SSI+LAAEDP+ S +N +L + D FT VFT E++LK+ G LH GS+CR+ +NILD VV +L++ MG + S ++ +K LRVLRVLRPL+ INR LK V CV ++K + NI++V +L F+FA I VQLF+GKFF+C D K + E CRG + Y + E ++R W + F+FDNIL ML LFTV+T EGWP +L +++S + + GP+ + R E++IF+IV+ I+ FF +NIFV +I+TFQEQGE E + +LDKNQ+QC+ +A+ +PL Y+PK+ +Y+VW +V S FEY + ++I LNT+ L M++ + S TH + LN FTV+F++E LK+ AF K YF DPWN+FDF+ V+GSI DV++SE+ + S+ RLFR RL+KLL + IR LLWTFI+SF+ALPYV LLI MLFFIY++IGMQVFG I LI INR+NNFQTF +L+LFRCATGE WQE+M C + C+ D + CG+ F +YF+SF L + ++ +++ + F ++ + + P R A+ +GRI H ++ +LR ++PP+GFGK CP+R+A ++LI MNMP++ +GTV F TLFAL+R +L IK T + ELR I K+W + K L+ ++PP + ++TVGK YA +LI E++R + QE+ PA Sbjct: 14 EETLKRKQREKLKKLQATGGNPRPARSLLFLTLKNPFRKACISIVEWKPFEIIILVTIFANCVALAVFMPMPEEDTNNTNSNLESLEYIFLIIFTLECFLKIVAYGLLFHADAYLRNCWNILDFVIVTMGLFTIAVDFINNISGVEAPVEQKGGGFDMKALRAFRVLRPLRLVSGVPSLQVVMSSILKSMLPLFHISLLVFFMVTIYAIIGLELFKCKMHKTCYYSGTDIVA-TVENEKA-SPCAEAGNGRRCTV----NGTVCKPGWPGPNDGITHFDNLGFSMLTVYQCITTQGWTDVLYWVNDAIGMEWPWLYFVTLILLGSFFILNMVLGVLCGSFTKEREKSSRSGEYQKLRERQQLDEDLKGYMDWITQA-EVMEND-----QDRQGLLPLQEGG-------------------SDTESLYELEGLN-----RLMYYVRHAR--------RWNRFFRRKCRVWVKSRLFYWLVFLLVFFNTLVIATEHHMQSQSLTNFQENSNTALLCMFAVEMVLKMYALGLPSYFMSLFNRFDCFVVSVGMLELILVHMGVMSAMGISVMRCIRLLRLIKVTKYWTSLSNLVASLLNSVRSIASLLLLLFLFIVIFALLGMQVFGGKFNFPDQEVRRSNFDNFPQALITVFQILTGEDWNSVMYDGIMAHGGPVIPGILVSIYFIILFVCGNYILLNVFLAIAVDNLAEAESLTSAQKEKAEEKKRKKLLRANLSDKGDEDKSTLAKKLAEQRAKTEGIPTTAKL------KVDEFESNVNEIKD---------PFPPADFPGDDEEEEPEIPTSPRPRPMADLQLKETVVPMPEASSFFIFGPQNKFRKLCHRIINATTFTNIILLFILLSSISLAAEDPIDPMSFRNQVLAYADIVFTSVFTAEIVLKMTTYGAFLHTGSFCRNSFNILDLIVVGVSLLS--MGMESSA------------ISVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIKTIGNIVLVTMLLDFMFACIGVQLFKGKFFFCTDPLKMTEEECRGTYIHYQENALHEMEVRQREWMNSGFNFDNILNGMLALFTVSTFEGWPKLLYTAIDSNSENMGPVYNNRTEISIFFIVYLILIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVQYALKARPLRCYIPKNP--YQYQVWYIVTSCYFEYLMFLLIMLNTMCLGMQHCNQ----SEHVTHLSDM------------LNVIFTVLFTVEMFLKLGAFKAKGYFGDPWNVFDFVIVVGSIVDVILSEIDAALAAQGGLYCLTGCANMSVSITLFRLFRVMRLVKLLNRFEGIRNLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALIDGTVINRNNNFQTFPQAVLVLFRCATGEGWQEVMQGCLYGQRCDPKSDYLPGEEYTCGAGFAVLYFMSFYMLFFIYAVIGIYIFSVFALFHFMHFMNCMNAP------CRCLAK-----LGRIKHLDVVTLLRRIQPPLGFGKFCPHRVACKRLISMNMPLNSDGTVTFNATLFALVRTALRIK--TEGNFQQANEELRAIIKKIWKRTSMKLLDQVIPPIGD---DEVTVGKFYATFLIQEHFRKFMKRQEEYYGYRPA 1544
BLAST of Voltage dependent L type calcium channel subunit vs. Ensembl Cavefish
Match: cacna1sa (calcium channel, voltage-dependent, L type, alpha 1S subunit, a [Source:ZFIN;Acc:ZDB-GENE-090514-1]) HSP 1 Score: 1022.31 bits (2642), Expect = 0.000e+0 Identity = 669/1640 (40.79%), Postives = 943/1640 (57.50%), Query Frame = 2 Query: 623 KTTSMRSLAKRTINLSFPGMQTSTSKSLFIFSEENVIRKYAKIIIEWGPFEYMVLLTILANCIVLSMERHLPKKDKTLLAGQLELTEKYFLGIFCVEALLKIVALGFCCHKEAYLRNVWNIMDFVVVVTGFLMMFLNIDNH---------SDSSTVDLRTLRAVRVLRPLKLVAGFPSLQVVLKSIIRAMAPLLQIGLLVLFAITIFAIIGLEFYSGAFHYTCFKANSDKLPLPIPTEKSLVPCSNSKNGSGLGAYTCPEDYQCKAYWEGPNYGITSFDNIGYAMLTVFQCITMEGWTDIMYHTNDAIGNRFNWLYFVPLIILGSFFMLNLVLGVLSGXXXXXXXXXXXXXXXLKLRRQQQTEKEFNGYMEWIQKAEEVLLNEATTTSEDKMRIIAARRRAEKQKYKLLGKNQSIPDFEYEDTELYSETKSMKGNIFIRSYAGIRRRRKERCTSFWRTEKHFRFSVRRLVKSQPFYWAVIILVFFNTVCVAIEHYEQGKWLTLFLNYAEYVFLCLFMMEMMIKMYGLSIRVYFQSSFNIFDCVVIAGSLFEIIYGIFVQDSSFGLSVLRALRLLRIFKVTRYWAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXGMQLFGGEFNFEEGKPPQ-NFDTFVKALLTVFQILTGEDWNTVMYNGIQSKGGVKERGTVFSIYFVLLVVFGNYTLLNVFLAIAVDNLANXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSSDNFIGRLPLSIDPPMVQVCPPSPQTANSLISKNFSFDHNQVEVNDKGCLLNTNKPNGKLGMLGHDNTNFNSLESDPVPNKIEPETIQRK--PVLPYSAMFIFSPLNSLRRFCHFVVNLRYFDLFIMIVICASSIALAAEDPVKEKSLKNNILEFFDYAFTGVFTVEMILKIIDLGIILHPGSYCRDLWNILDATVVICALVAFIMGQKPSPTGNKLRGSSAKNLNTIKSLRVLRVLRPLKTINRVPKLKAVFDCVVSSLKNVFNILIVYILFQFIFAVIAVQLFQGKFFYCNDASKSSRETCRGYFFDYAGRSTP--ETKKRLWQHHDFHFDNILYAMLTLFTVTTGEGWPTVLKNSMESTNIDNGPIADYRQEMAXXXXXXXXXXXXXXXXXXXALIIITFQEQGENELIDLDLDKNQKQCIDFAINEKPLCRYMPKDKTTIKYRVWRLVVSTPFEYFIMVMIALNTLILMMKYYREEKKASSAATHDREQQAYLNYCNTLIFLNSAFTVMFSIECVLKIMAFGPKNYFRDPWNIFDFITVIGSITDVLVSEL------------------QDXXXXXXXXXXXXXXXXXXXXXXQGYTIRILLWTFIQSFKALPYVCLLIAMLFFIYSIIGMQVFGNIKLISEYQINRHNNFQTFTNGLLLLFRCATGESWQEIMLACDNNKPCE--KDIENTNNFDCGSNFTYIYFVSFIFLCSFLMLNLFVAVIMDNFDYLTRDSSILGPHHLDEYIRVWAEYDPGAIGRIHHSEMYEMLRNMEPPVGFGKKCPYRLAYRKLIRMNMPVDENGTVNFTTTLFALIRESLNIKMSTAEYMDIKDMELRQTICKMWPVQAKKKLNLIVPPDSELVFHKMTVGKIYAGYLIVENWRAYKNSQEQGPRSSPA 5440 + T R ++ L G ++SL + +N RK I+EW PFE ++L+TI ANC+ L++ +P++D LE E FL IF +E LKIVA G H +AYLRN WNI+DFV+V G + ++ N+ D++ LRA RVLRPL+LV+G PSLQVV+ SI+++M PL I LLV F +TI+AIIGLE + H TC+ + +D + + EK+ PC+ + NG CK W GPN GIT FDN+G++MLTV+QCIT +GWTD++Y NDAIG + WLYFV LI+LGSFF+LN+VLGVL G +EE + ++ + + ++R KL G+ +S D T+ ++++S+ R R F+R + R VKS+ FYW V +LVFFNT+ +A EH+ Q + LT F + LC+F +EM++KMY L + YF S FN FDC V++ + E+I S+ G+SV+R +RLLR+ KVT+YW SL NLV SLLNS+RSI SLL LLFLFI+IFALLGMQ+FGG+FNF + + + NFD F +AL+TVFQILTGEDWN+VMY+GI + GG G + SIYF++L V GNY LLNVFLAIAVDNLA A+ LT+A++EKA E +R A ++ +L P TA + + F+ N E+ D P G D + + P P + ++ P+ S+ FIF P N R+ CH ++N F I++ I SSI+LAAEDP+ S +N +L + D FT VFT E++LK+ G LH GS+CR+ +NILD VV +L++ MG + S ++ +K LRVLRVLRPL+ INR LK V CV ++K + NI++V +L F+FA I VQLF+GKFF+C D K + E CRG + Y + E ++R W + F+FDNIL ML LFTV+T EGWP +L +++S + + GP+ + R E++IF+IV+ I+ FF +NIFV +I+TFQEQGE E + +LDKNQ+QC+ +A+ +PL Y+PK+ +Y+VW +V S FEY + ++I LNT+ L M++ + S TH + LN FTV+F++E LK+ AF K YF DPWN+FDF+ V+GSI DV++SE+ ++ +S+ RLFR RL+KLL + IR LLWTFI+SF+ALPYV LLI MLFFIY++IGMQVFG I LI INR+NNFQTF +L+LFRCATGE WQE+M C + C+ D + CG+ F +YF+SF L F+ ++ + + S+ H ++ + GRI H ++ +LR ++PP+GFGK CP+R+A ++LI MNMP++ +GTV F TLFAL+R +L IK T + ELR I K+W + K L+ ++PP + ++TVGK YA +LI E++R + QE+ PA Sbjct: 23 EETLKRKQREKLKKLQATGGNPRPARSLLFLTLKNPFRKACISIVEWKPFEIIILVTIFANCVALAVFMPMPEEDTNNTNSNLESLEYIFLIIFTLECFLKIVAYGLLFHADAYLRNCWNILDFVIVTMGLFTIAVDFINNISGVEAPVEQKGGGFDMKALRAFRVLRPLRLVSGVPSLQVVMSSILKSMLPLFHISLLVFFMVTIYAIIGLELFKCKMHKTCYYSGTDIVA-TVENEKA-SPCAEAGNGRRCTV----NGTVCKPGWPGPNDGITHFDNLGFSMLTVYQCITTQGWTDVLYWVNDAIGMEWPWLYFVTLILLGSFFILNMVLGVLCGSV-----------------------------------SEESMAHD--------LLMFGIKKRV-----KLTGRTRSTMD---SQTQRQNQSESLIW------------RHARRWNRFFRRK------CRVWVKSRLFYWLVFLLVFFNTLVIATEHHMQSQSLTNFQENSNTALLCMFAVEMVLKMYALGLPSYFMSLFNRFDCFVVSVGMLELILVHMGVMSAMGISVMRCIRLLRLIKVTKYWTSLSNLVASLLNSVRSIASLLLLLFLFIVIFALLGMQVFGGKFNFPDQEVRRSNFDNFPQALITVFQILTGEDWNSVMYDGIMAHGGPVIPGILVSIYFIILFVCGNYILLNVFLAIAVDNLAEAESLTSAQKEKAEEKKRKKLANLSDKGDEDKSTLAKKL-----AEQRAKTEGIPTTAKLKVDE---FESNVNEIKD---------PFPPADFPGDDEEEEPEIPTSPRPRPMADLQLKETVVPMPEASSFFIFGPQNKFRKLCHRIINATTFTNIILLFILLSSISLAAEDPIDPMSFRNQVLAYADIVFTSVFTAEIVLKMTTYGAFLHTGSFCRNSFNILDLIVVGVSLLS--MGMESSA------------ISVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIKTIGNIVLVTMLLDFMFACIGVQLFKGKFFFCTDPLKMTEEECRGTYIHYQENALHEMEVRQREWMNSGFNFDNILNGMLALFTVSTFEGWPKLLYTAIDSNSENMGPVYNNRTEISIFFIVYLILIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVQYALKARPLRCYIPKNP--YQYQVWYIVTSCYFEYLMFLLIMLNTMCLGMQHCNQ----SEHVTHLSDM------------LNVIFTVLFTVEMFLKLGAFKAKGYFGDPWNVFDFVIVVGSIVDVILSEIDAALAAQGGLYCLTGCADSENMSVSITLFRLFRVMRLVKLLNRFEGIRNLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALIDGTVINRNNNFQTFPQAVLVLFRCATGEGWQEVMQGCLYGQRCDPKSDYLPGEEYTCGAGFAVLYFMSFYML-------FFIYAVIGIYIF-----SVFALFHFMHFMNC---MNAPCRGRIKHLDVVTLLRRIQPPLGFGKFCPHRVACKRLISMNMPLNSDGTVTFNATLFALVRTALRIK--TEGNFQQANEELRAIIKKIWKRTSMKLLDQVIPPIGD---DEVTVGKFYATFLIQEHFRKFMKRQEEYYGYRPA 1518
BLAST of Voltage dependent L type calcium channel subunit vs. Ensembl Cavefish
Match: cacna1sb (calcium channel, voltage-dependent, L type, alpha 1S subunit, b [Source:ZFIN;Acc:ZDB-GENE-051227-1]) HSP 1 Score: 966.066 bits (2496), Expect = 0.000e+0 Identity = 643/1660 (38.73%), Postives = 912/1660 (54.94%), Query Frame = 2 Query: 638 RSLAKRTINLSFPGMQTSTSKSLFIFSEENVIRKYAKIIIEWGPFEYMVLLTILANCIVLSMERHLPKKDKTLLAGQLELTEKYFLGIFCVEALLKIVALGFCCHKEAYLRNVWNIMDFVVVVTGFLMMFLNIDNH------SDSSTVDLRTLRAVRVLRPLKLVAGFPSLQVVLKSIIRAMAPLLQIGLLVLFAITIFAIIGLEFYSGAFHYTCFKANSDKLPL---PIPTEKSLVPCSNSKNGSGLGAYTCP-EDYQCKAYWEGPNYGITSFDNIGYAMLTVFQCITMEGWTDIMYHTNDAIGNRFNWLYFVPLIILGSFFMLNLVLGVLSGXXXXXXXXXXXXXXXLKLRRQQQTEKEFNGYMEWIQKAEEVLLNEATTTSEDKMRIIAARRRAEKQKYKLLGKNQSIPDFEYEDTELYSETKSMKGNIFIRSYAGIRRRRKERCTSFWRTEKHFRFSVRRLVKSQPFYWAVIILVFFNTVCVAIEHYEQGKWLTLFLNYAEYVFLCLFMMEMMIKMYGLSIRVYFQSSFNIFDCVVIAGSLFEIIYGIFVQDSSFGLSVLRALRLLRIFKVTRYWAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXGMQLFGGEFNFEEGKPPQNFDTFVKALLTVFQILTGEDWNTVMYNGIQSKGGVKERGTVFSIYFVLLVVFGNYTLLNVFLAIAVDNLANXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSSDNFIGRLPLSIDPPMVQVCPPSPQTANSLISKNFSFDHNQVEVNDKGCLLNTNKPNGKLGMLGHDNTNFNSLESDPVPNKIEPETIQRKPV-LPYSAMF-IFSPLNSLRRFCHFVVNLRYFDLFIMIVICASSIALAAEDPVKEKSLKNNILEFFDYAFTGVFTVEMILKIIDLGIILHPGSYCRDLWNILDATVVICALVAFIMGQKPSPTGNKLRGSSAKNLNTIKSLRVLRVLRPLKTINRVPKLKAVFDCVVSSLKNVFNILIVYILFQFIFAVIAVQLFQGKFFYCNDASKSSRETCRGYFFDYAGRS--TPETKKRLWQHHDFHFDNILYAMLTLFTVTTGEGWPTVLKNSMESTNIDNGPIADYRQEMAXXXXXXXXXXXXXXXXXXXALIIITFQEQGENELIDLDLDKNQKQCIDFAINEKPLCRYMPKDKTTIKYRVWRLVVSTPFEYFIMVMIALNTLILMMKYYREEKKASSAATHDREQQAYLNYCNTLIFLNSAFTVMFSIECVLKIMAFGPKNYFRDPWNIFDFITVIGSITDVLVSELQDXX--------------------XXXXXXXXXXXXXXXXXXXXQGYTIRILLWTFIQSFKALPYVCLLIAMLFFIYSIIGMQVFGNIKLISEYQINRHNNFQTFTNGLLLLFRCATGESWQEIMLACDNNKPCE--KDIENTNNFDCGSNFTYIYFVSFIFLCSFLMLNLFVAVIMDNFDYLTRDSSILGPHHLDEYIRVWAEYDPGAIGRIHHSEMYEMLRNMEPPVGFGKKCPYRLAYRKLIRMNMPVDENGTVNFTTTLFALIRESLNIKMSTAEYMDIKDMELRQTICKMWPVQAKKKLNLIVPPDSELVFHKMTVGKIYAGYLIVENWRAYKNSQEQ----GPRSSPAVSIKSVTKPVVKEEKSANL 5497 R ++ L G ++SLF F+ +N RK I+EW PFE ++LLTI ANC+ L++ +P++D LE E FL IF +E LKI+A G H+ AYLRN WNI+DFV+V G + ++ N D++ LRA RVLRPL+LV+G PSLQVV+ SI++AM PL Q+ LLV F +T+FAI+GLE Y H TC+ +D + L +P+ PC+ + NG C +C+ W GPN+GIT FDN G+AMLTVFQCITME WT+++Y NDA+GN + W+YFV +I+LGSFF+LNLVLGVLSGEF+KERE+ R + KLR +QQ +++ GYMEWI AE + A+++ LL + D + E L+ +++G I Y + RR W + FR VKS+ FYW VI++VF NT+ +A EH+ Q + T F + A + L F EM KMY +R YF S FN FD V+ + EII + G+SV+R +RLLR K+T+ + +Q+ GE +DT + +N +M +G G + G + SIYF++L V GN+ LLNVFLAIAVDNL A+ L++A++EK E R E+ + P TA + + F+ N EV D P G D + P P + ++ V +P ++ F IF P N R+ CH +N F FI+++I SSI+LAAED + KS +N IL + D FT VFT+E++LK+ G ILH GS+CR+ +NILD VV+ +L++ G + ++ IK LRVLRVLRPL+ +NR LK V SL+ L + +L + +F ++ T +G F + S E +R W + DF+FDN+ AML LFTV+T EGWP +L +++S D GP+ + R + ++F++++ I+ FF +NIFV +I+TF+EQGE E + +LDKNQ+QC+ +A+ +PL Y+PK+ +YRVW LV S FEY + ++I LNT L +++ + + A LN FTV+F+ E ++K++AF K YF DPWN+FDF+ VIGSI DV++S++ + +S+ F RLFR RLIKLL + IR LLWTFI+SF+A P+V LLI MLFFIY++IGMQVFG I L+ +INR+ NFQTF +L+L+R TGE WQ++MLAC + K C+ D + CG+NF YF+SF +C FL++NLFVAVIMDNFDYLTRD SILGPHHLDE+ ++WAEYDP A GRI H ++ +LR ++PP+GFGK CP+R A R+LI MNMP++ +GTV F TLFAL+R L+IK T + + ELR I +W + K L+ ++PP E ++TVGK YA +LI E++R + QE+ P A I++ + ++EE + L Sbjct: 21 RKQREKLKKLQATGGNPRPARSLFFFTLKNPFRKACTKIVEWKPFEIIILLTIFANCVALAVFLPMPEEDTNYTNTTLESLEYIFLVIFTLECFLKIIAYGLLFHEGAYLRNCWNILDFVIVFMGLFTLAVDTINAIAGTPTEKGGGFDMKALRAFRVLRPLRLVSGVPSLQVVMNSILKAMIPLFQVVLLVFFLVTLFAIMGLELYKCKMHKTCYYEGTDIIALRENEVPS-----PCAQAGNGR-----RCTINGTECRGGWPGPNFGITHFDNFGFAMLTVFQCITMESWTNVLYWVNDAVGNEWAWIYFVTMILLGSFFVLNLVLGVLSGEFSKEREKCRSRGEYQKLRERQQMDEDLKGYMEWITHAEVL--------------------DADQEGQGLL----PLKDSDSESEILF----AIEGLNRIAYYYRLARR--------W--NRVFRLKCAVWVKSRMFYWLVILVVFLNTLVIACEHHPQSESATRFQDVANDILLTCFAFEMFAKMYAFGLRAYFMSVFNRFDFFVVTVGILEIILVAADVMTPLGISVMRCIRLLRFVKITKLYHIF--------------------------------IQVITGE----------EWDTIM--------------YNGIMAHG-----GPQSPGILVSIYFIILYVVGNFILLNVFLAIAVDNLTEAESLSSAQKEKEEEKARKKLMRTAPPHEEEKAKLVKS---------KHKTEGMPTTAKLKVDE---FESNVKEVKD---------PFPPADFPGDDEEEEPEIPISPRPRPMADLQLKETVVPMPEASSFFIFGPENKFRKLCHRAINATPFTNFILLLILLSSISLAAEDAIDPKSFRNKILAYADIVFTTVFTIEIVLKMTVYGAILHTGSFCRNAFNILDLIVVVVSLLSM--------------GLESSAISVIKILRVLRVLRPLRALNRAKGLK------VCSLETRIIQLNMNMLPEVLFTLLGT-------------------TVKGTFVKHVRNSLHDKEIGQRQWVNSDFNFDNVPNAMLALFTVSTFEGWPELLYKAIDSDAEDRGPVFNNRMDTSLFFVIYLIIIAFFMMNIFVGFVIVTFREQGEQEFKNCELDKNQRQCVQYALKARPLRCYIPKNP--YQYRVWYLVTSCYFEYLMFLLIILNTCSLGLQHCNQSDHITKLADT----------------LNVIFTVLFTFEMIVKLIAFKAKGYFGDPWNVFDFLIVIGSIVDVVLSQVDAALESSGGLYCLHGCTVNISLHCMVSITFFRLFRVLRLIKLLNRSEGIRNLLWTFIKSFQAFPHVALLIVMLFFIYAVIGMQVFGKIALVDGTEINRNANFQTFPQAILILYRTVTGEGWQKLMLACMSGKLCDPRSDYAPGEEYTCGTNFAVFYFLSFNMICGFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKKIWAEYDPEATGRIKHLDVVTLLRRIQPPLGFGKFCPHRSACRRLISMNMPLNSDGTVTFNATLFALVRTDLSIK--TEGNFEQANEELRLIIKSIWKRTSMKLLDQVIPPIGE---DEVTVGKFYATFLIQEHFRKFMKRQEEYYGYRPTKKSAAEIQAGLR-TIEEEAAPEL 1487
BLAST of Voltage dependent L type calcium channel subunit vs. Ensembl Cavefish
Match: cacna1bb (calcium channel, voltage-dependent, N type, alpha 1B subunit, b [Source:ZFIN;Acc:ZDB-GENE-090514-4]) HSP 1 Score: 932.939 bits (2410), Expect = 0.000e+0 Identity = 493/844 (58.41%), Postives = 634/844 (75.12%), Query Frame = 2 Query: 2954 LNTNKPNGKLGMLGHDNTNFNSLE-SDPVPNKIEPETIQRKPVLPYSAMFIFSPLNSLRRFCHFVVNLRYFDLFIMIVICASSIALAAEDPVKEKSLKNNILEFFDYAFTGVFTVEMILKIIDLGIILHPGSYCRDLWNILDATVVICALVAFIMGQKPSPTGNKLRGSSAKNLNTIKSLRVLRVLRPLKTINRVPKLKAVFDCVVSSLKNVFNILIVYILFQFIFAVIAVQLFQGKFFYCNDASKSSRETCRGYFFDYAGRSTPETKKRLWQHHDFHFDNILYAMLTLFTVTTGEGWPTVLKNSMESTNIDNGPIADYRQEMAXXXXXXXXXXXXXXXXXXXALIIITFQEQGENELIDLDLDKNQKQCIDFAINEKPLCRYMPKDKTTIKYRVWRLVVSTPFEYFIMVMIALNTLILMMKYYREEKKASSAATHDREQQAYLNYCNTLIFLNSAFTVMFSIECVLKIMAFGPKNYFRDPWNIFDFITVIGSITDVLVSELQDXXXXXXXXXXXXXXXXXXXXXXQGYTIRILLWTFIQSFKALPYVCLLIAMLFFIYSIIGMQVFGNIKLISEYQINRHNNFQTFTNGLLLLFRCATGESWQEIMLACDNNKPCEKDIENTNNFDCGSNFTYIYFVSFIFLCSFLMLNLFVAVIMDNFDYLTRDSSILGPHHLDEYIRVWAEYDPGAIGRIHHSEMYEMLRNMEPPVGFGKKCPYRLAYRKLIRMNMPVDENGTVNFTTTLFALIRESLNIKMSTAEYMD-IKDMELRQTICKMWPVQAKKKLNLIVPPDSELVFHKMTVGKIYAGYLIVENWRA--YKNSQEQGPRSSPAVSIKSVTKPVV 5473 + P G+ ++ +N + +SL S+ + E I K +LPYS+MF+F N +RR CH+VVNLRYF++ I+ VI SSIALAAEDPV+ + +NN+L++ DY FTGVFT EM++K+IDLG++LHPGSY RDLWNILD VV ALVAF GS K++NTIKSLRVLRVLRPLKTI R+PKLKAVFDCVV+SLKNV NILIVYILF FIFAVIAVQLF+GKFFYC D SK+ ++ CRG F DY G + R W+ ++FH+DN+L+A LTLFTV+TGEGWP VLK+S+++T D GP YR E +IFY+V+F+VFPFFFVNIFVALIIITFQEQG+ + D L+KN++ CIDFAIN KPL RYMP+DK + +Y++W+ VVSTPFEY I+ MIA+NT++LMMK++ K Y + L +LN FT +F++EC+LKI+AFG NY ++ WNIFDF+TV+GSITD+LV+E++ ++L FLRLFRAARLIKLLRQGYTIRILLWTF+QSFKALPYVCLLIAMLFFIY+IIGMQVFGNI L + IN HNNF+TF L+LLFR ATGE+W EIMLAC + KPC+ + ++ +CGS F Y YFVSFIFLCSFLMLNLFVAVIMDNF+YLTRD+SILGPHHLDE+IRVWAEYDP A GRI + +MYEMLR+M PP+G GKKCP R+AY++L+RMNMP+ ++ TV+FT+TL ALIR +L+IK+++ + D++LR+ I K+WP K ++L+V P +++TVGK+YA +I + ++ K Q+Q P P + ++ KP++ Sbjct: 1048 VTVTAPPGETTIIPMNNIDGDSLLLSEEKKDLDELNQIPPKHILPYSSMFVFGQSNPVRRLCHYVVNLRYFEMCILTVITMSSIALAAEDPVQANAPRNNVLKYLDYVFTGVFTFEMVIKMIDLGLLLHPGSYFRDLWNILDFIVVTGALVAFACS-----------GSKGKDINTIKSLRVLRVLRPLKTIKRLPKLKAVFDCVVNSLKNVLNILIVYILFMFIFAVIAVQLFKGKFFYCTDESKALQKDCRGQFLDYDGDEV-SAQPREWKKYEFHYDNVLWAFLTLFTVSTGEGWPMVLKHSVDATYEDQGPSPGYRMETSIFYVVYFVVFPFFFVNIFVALIIITFQEQGDKAMSDCSLEKNERACIDFAINAKPLTRYMPQDKQSYQYKMWKFVVSTPFEYSILTMIAVNTVVLMMKFHEAPKP----------------YEDMLKWLNIIFTALFTLECILKIIAFGLLNYLKEAWNIFDFVTVLGSITDILVTEIKQDKLINLSFLRLFRAARLIKLLRQGYTIRILLWTFVQSFKALPYVCLLIAMLFFIYAIIGMQVFGNIDLNEDTSINHHNNFRTFFQALMLLFRSATGEAWHEIMLACLSEKPCDP-LSGSSEKECGSEFAYFYFVSFIFLCSFLMLNLFVAVIMDNFEYLTRDASILGPHHLDEFIRVWAEYDPAACGRISYLDMYEMLRHMSPPLGLGKKCPSRIAYKRLVRMNMPIADDNTVHFTSTLMALIRTALDIKLASGVLAQRLCDIDLRREINKVWPSLQPKTVDLLVTPHKH---NELTVGKVYAALMIFDYYKQNRAKRLQQQQPSVGPQSKMGALFKPML 1859 HSP 2 Score: 717.613 bits (1851), Expect = 0.000e+0 Identity = 415/682 (60.85%), Postives = 507/682 (74.34%), Query Frame = 2 Query: 689 STSKSLFIFSEENVIRKYAKIIIEWGPFEYMVLLTILANCIVLSMERHLPKKDKTLLAGQLELTEKYFLGIFCVEALLKIVALGFCCHKEAYLRNVWNIMDFVVVVTGFLMMFLNIDNHSDSSTVDLRTLRAVRVLRPLKLVAGFPSLQVVLKSIIRAMAPLLQIGLLVLFAITIFAIIGLEFYSGAFHYTCFKANSDKLPLPIPTEKSLVPCSNSKNGSGLGAYTCPEDYQCKAYWEGPNYGITSFDNIGYAMLTVFQCITMEGWTDIMYHTNDAIGNRFNWLYFVPLIILGSFFMLNLVLGVLSGXXXXXXXXXXXXXXXLKLRRQQQTEKEFNGYMEWIQKAEEVLLNEATTTSEDKMRIIAARRRAEKQKYKLL-------GKNQSIPDFEYEDTELYSETKSMKGNIFIRSYAGIRRRRKERCTSFWRTEKHFRFSVRRLVKSQPFYWAVIILVFFNTVCVAIEHYEQGKWLTLFLNYAEYVFLCLFMMEMMIKMYGLSIRVYFQSSFNIFDCVVIAGSLFEIIYGIFVQDSSFGLSVLRALRLLRIFKVTRYWAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXGMQLFGGEFNFEEGKPPQNFDTFVKALLTVFQILTGEDWNTVMYNGIQSKGGVKERGTVFSIYFVLLVVFGNYTLLNVFLAIAVDNLAN 2713 + ++SLFIFSE+NVIRKYAK I EW PFEYM+L TI+ANCIVL++E+HLP DKT ++ +L+ TE YF+GIFC EA +KI+ALGF HK +YLRN WN+MDFVVV+TG L S DLRTLRAVRVLRPLKLV+G PSLQVVLKSI++AM PLLQIGLL+ FAI +FAIIG+EFY G FH +CFK + + S PC G+ + CP C+ YW+GPNYGIT+FDNI +A+LTVFQCITMEGW D++Y TNDA GN +NWLYF+PLII+GSFFMLNLVLGVLSGEFAKERERVEKR+ FLKLRRQQQ E+E GY+EWI KAEEVLL E +E+K + A + KQ +L GKN I E E+ + + G+ F R A ++ + + + F R EK RF +RR+VK+Q FYW V+ +V NT+CVA+ HY+Q WL+ L AE+VFL LF+ EM +KMYGL R YF SSFN FD VI GS+FE+++ +SFG+SVLRALRLLRIFKVT+YW SLRNLV+SLLNSM+SIISLLFLLFLFI++FALLGMQLFGG+FNF++ P NFD F A++TVFQILTGEDWN VMY+GI+S+GGV+ RG SIYF++L +FGNYTLLNVFLAIAVDNLAN Sbjct: 55 TVNRSLFIFSEDNVIRKYAKRITEWPPFEYMILATIIANCIVLALEQHLPVGDKTPMSERLDDTEPYFIGIFCFEAGIKIIALGFVFHKGSYLRNGWNVMDFVVVLTGILATV--------GSDFDLRTLRAVRVLRPLKLVSGIPSLQVVLKSIMKAMVPLLQIGLLLFFAIVMFAIIGVEFYMGKFHTSCFKESGEL--------ASDWPC-----GTEAPSRLCPNGTVCRTYWKGPNYGITNFDNILFAVLTVFQCITMEGWVDVLYSTNDASGNTWNWLYFIPLIIIGSFFMLNLVLGVLSGEFAKERERVEKRQEFLKLRRQQQIERELTGYLEWICKAEEVLLAEEDQNAEEKSPLDGAWYK-RKQNNPVLKRAKVKKGKNDLISAEEGEERFTDISSVAPPGSPFAR--ASLKSSKNDSSSYFRRKEKRVRFFIRRMVKAQSFYWIVLCIVGLNTLCVAMVHYDQPDWLSQALYLAEFVFLGLFLSEMTLKMYGLGPRNYFHSSFNCFDFGVIVGSIFEVVWAAIQPGASFGISVLRALRLLRIFKVTKYWNSLRNLVVSLLNSMKSIISLLFLLFLFIVVFALLGMQLFGGQFNFDKETPTTNFDNFPAAIMTVFQILTGEDWNAVMYHGIESQGGVR-RGMFSSIYFIVLTLFGNYTLLNVFLAIAVDNLAN 711 HSP 3 Score: 121.709 bits (304), Expect = 8.705e-27 Identity = 81/272 (29.78%), Postives = 139/272 (51.10%), Query Frame = 2 Query: 3092 AMFIFSPLNSLRRFCHFVVNLRYFDLFIMIVICASSIALAAED--PVKEKSLKNNILEFFDYAFTGVFTVEMILKIIDLGIILHPGSYCRDLWNILDATVVICALVAFIMGQKPSPTGNKLRGSSAKNLNTIKSLRVLRVLRPLKTINRVPKLKAVFDCVVSSLKNVFNILIVYILFQFIFAVIAVQLFQGKFFYCNDASKSSRETCRGY--FFDYAGRSTPETK--KRLWQHHDF---HFDNILYAMLTLFTVTTGEGWPTVLKNSMESTN 3880 ++FIFS N +R++ + F+ I+ I A+ I LA E PV +K+ + L+ + F G+F E +KII LG + H GSY R+ WN++D VV+ ++A + GS +++LR +RVLRPLK ++ +P L+ V ++ ++ + I ++ +FA+I V+ + GKF K S E + + R P + W+ ++ +FDNIL+A+LT+F T EGW VL ++ +++ Sbjct: 59 SLFIFSEDNVIRKYAKRITEWPPFEYMILATIIANCIVLALEQHLPVGDKTPMSERLDDTEPYFIGIFCFEAGIKIIALGFVFHKGSYLRNGWNVMDFVVVLTGILATV-------------GSDFD----LRTLRAVRVLRPLKLVSGIPSLQVVLKSIMKAMVPLLQIGLLLFFAIVMFAIIGVEFYMGKFH--TSCFKESGELASDWPCGTEAPSRLCPNGTVCRTYWKGPNYGITNFDNILFAVLTVFQCITMEGWVDVLYSTNDASG 311 HSP 4 Score: 114.775 bits (286), Expect = 9.346e-25 Identity = 71/272 (26.10%), Postives = 133/272 (48.90%), Query Frame = 2 Query: 701 SLFIFSEENVIRKYAKIIIEWGPFEYMVLLTILANCIVLSMERHLPKKDKTLLAGQLELTEKYFLGIFCVEALLKIVALGFCCHKEAYLRNVWNIMDFVVVVTGFLMMFLNIDNHSDSSTVDLRTLRAVRVLRPLKLVAGFPSLQVVLKSIIRAMAPLLQIGLLVLFAITIFAIIGLEFYSGAFHYTCFKANSDKLPLPIPTEKSLVPCSNSKNGSGLGAYTCPEDYQCKAYWEGPNYGITSFDNIGYAMLTVFQCITMEGWTDIMYHTNDA 1516 S+F+F + N +R+ ++ FE +L I + I L+ E P + L+ + F G+F E ++K++ LG H +Y R++WNI+DF+VV + + D +T+ ++LR +RVLRPLK + P L+ V ++ ++ +L I ++ + + IFA+I ++ + G F Y ++ + +K +G + A P +++ + +DN+ +A LT+F T EGW ++ H+ DA Sbjct: 1095 SMFVFGQSNPVRRLCHYVVNLRYFEMCILTVITMSSIALAAED--PVQANAPRNNVLKYLDYVFTGVFTFEMVIKMIDLGLLLHPGSYFRDLWNILDFIVVTGALVAFACSGSKGKDINTI--KSLRVLRVLRPLKTIKRLPKLKAVFDCVVNSLKNVLNILIVYILFMFIFAVIAVQLFKGKFFYCTDESKA--------LQKDCRGQFLDYDGDEVSAQ--PREWKKYEF---------HYDNVLWAFLTLFTVSTGEGWPMVLKHSVDA 1343 HSP 5 Score: 97.0561 bits (240), Expect = 2.372e-19 Identity = 72/255 (28.24%), Postives = 139/255 (54.51%), Query Frame = 2 Query: 1970 EKHFRFSVRRLVKSQPFYWAVIILVFFNTVCVAIEHYEQGKWLTLFLNYAEYVFLCLFMMEMMIKMYGLSIRVYFQSSFNIFDCVVIAGSLFEIIYGIFVQDSSFGLSVLRALRLLRIFKVTRYWAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXGMQLFGG-EFNFEEG-KPPQNFDTFVKALLTVFQILTGEDWNTVMYNGIQSK-------GGVKERGTVFS-IYFVLLVVFGNYTLLNVFLAIAVDN 2704 ++ +++ + + V S PF ++++ ++ NTV + ++ +E K L + +F LF +E ++K+ + Y + ++NIFD V + GS+ +I+ QD LS LR R R+ K+ R ++R L+ + + S +++ + L+ + I+A++GMQ+FG + N + NF TF +AL+ +F+ TGE W+ +M + K KE G+ F+ YFV + ++ +LN+F+A+ +DN Sbjct: 1423 KQSYQYKMWKFVVSTPFEYSILTMIAVNTVVLMMKFHEAPKPYEDMLKWLNIIFTALFTLECILKIIAFGLLNYLKEAWNIFDFVTVLGSITDILVTEIKQDKLINLSFLRLFRAARLIKLLRQGYTIRILLWTFVQSFKALPYVCLLIAMLFFIYAIIGMQVFGNIDLNEDTSINHHNNFRTFFQALMLLFRSATGEAWHEIMLACLSEKPCDPLSGSSEKECGSEFAYFYFVSFIFLCSFLMLNLFVAVIMDN 1677 HSP 6 Score: 90.8929 bits (224), Expect = 1.683e-17 Identity = 73/290 (25.17%), Postives = 141/290 (48.62%), Query Frame = 2 Query: 4097 YMPKDKTTIKYRVWRLVVSTPFEYFIMVMIALNTLILMMKYYREEKKASSAATHDREQQAYLNYCNTLIFLNSAFTVMFSIECVLKIMAFGPKNYFRDPWNIFDFITVIGSITDVLVSELQDXXXXXXXXXXXXXXXXXXXXXXQGYTIRILLWTFIQSFKALPYVCLLIAMLFFIYSIIGMQVFGNIKLISEYQINRH---NNFQTFTNGLLLLFRCATGESWQEIMLACDNNKPCEKDIENTNNFDCGSNFTYIYFVSFIFLCSFLMLNLFVAVIMDNF---DYLTRD 4948 Y + + +++ + R+V + F + ++ ++ LNTL + M +Y + S A Y +FL +F E LK+ GP+NYF +N FDF ++GSI +V+ + +Q + + LR R R+ K+ + ++R L+ + + S K++ + L+ + +++++GMQ+FG ++ ++ NF F ++ +F+ TGE W +M IE+ G F+ IYF+ ++ +LN+F+A+ +DN LT+D Sbjct: 460 YFRRKEKRVRFFIRRMVKAQSFYWIVLCIVGLNTLCVAMVHYDQPDWLSQAL-----------YLAEFVFLG-----LFLSEMTLKMYGLGPRNYFHSSFNCFDFGVIVGSIFEVVWAAIQPGASFGISVLRALRLLRIFKVTKYWNSLRNLVVSLLNSMKSIISLLFLLFLFIVVFALLGMQLFGG-----QFNFDKETPTTNFDNFPAAIMTVFQILTGEDWNAVMY---------HGIESQGGVRRGM-FSSIYFIVLTLFGNYTLLNVFLAIAVDNLANAQELTKD 718 HSP 7 Score: 79.7221 bits (195), Expect = 4.942e-14 Identity = 74/292 (25.34%), Postives = 118/292 (40.41%), Query Frame = 2 Query: 767 PFEYMVLLTILANCIVLSMERHLPKKDKTLLAGQLELTEKYFLGIFCVEALLKIVALGFCCHKEAYLRNVWNIMDFVVVVTGFLMMFLNIDNHSDSSTVDLRTLRAVRVLRPLKLVAGFPSLQVVLKSIIRAMAPLLQIGLLVLFAITIFAIIGLEFYSGAFHYTCFKANSDKLPLPIPTEKSLVPCSNSKNGSGLGAYTCPEDYQCKAYWEGPNYGITSFDNIGYAMLTVFQCITMEGWTDIMY-------------HTNDAIGNRFNWLYFVPLIILGSFFMLNLVLGVL 1603 PFEY +L I N +VL M+ H K + L + F +F +E +LKI+A G YL+ WNI DFV V+ G + L + D ++L LR R R +KL+ +++++L + +++ L + LL+ I+AIIG++ + G ED + +F A++ +F+ T E W +IM + G+ F + YFV I L SF MLNL + V+ Sbjct: 1438 PFEYSILTMIAVNTVVLMMKFHEAPKPYEDMLKWLNII---FTALFTLECILKIIAFGLL----NYLKEAWNIFDFVTVL-GSITDILVTEIKQD-KLINLSFLRLFRAARLIKLLRQGYTIRILLWTFVQSFKALPYVCLLIAMLFFIYAIIGMQVF--------------------------------------GNIDLNEDTSINHH--------NNFRTFFQALMLLFRSATGEAWHEIMLACLSEKPCDPLSGSSEKECGSEFAYFYFVSFIFLCSFLMLNLFVAVI 1674 HSP 8 Score: 54.299 bits (129), Expect = 2.516e-6 Identity = 55/251 (21.91%), Postives = 117/251 (46.61%), Query Frame = 2 Query: 3122 LRRFCHFVVNLRYFDLFIMIVICASSIALAAEDPVKEKSLKNNILEFFDYAFTGVFTVEMILKIIDLGIILHPGSYCRDLWNILDATVVICALVAFIMGQKPSPTGNKLRGSSAKNLNTIKSLRVLRVLRPLKTINRVPKLKAVFDCVVSSLKNVFNILIVYILFQFIFAVIAVQLFQGKFFYCNDASKSSRETCRGYFFDYAGRSTPETKKRLWQHHDFHFDNILYAMLTLFTVTTGEGWPTVLKNSMES 3874 +R F +V + F ++ ++ +++ +A + + L ++ F G+F EM LK+ LG P +Y +N D V++ ++ + ++ ++ ++ +++LR+LR+ + K N L+ + +++S+K++ ++L + LF +FA++ +QLF G+F + + TP T +FDN A++T+F + TGE W V+ + +ES Sbjct: 468 VRFFIRRMVKAQSFYWIVLCIVGLNTLCVAMVH-YDQPDWLSQALYLAEFVFLGLFLSEMTLKMYGLG----PRNYFHSSFNCFDFGVIVGSIFEVVWA--------AIQPGASFGISVLRALRLLRIFKVTKYWN---SLRNLVVSLLNSMKSIISLLFLLFLFIVVFALLGMQLFGGQFNF--------------------DKETPTT----------NFDNFPAAIMTVFQILTGEDWNAVMYHGIES 672
BLAST of Voltage dependent L type calcium channel subunit vs. Ensembl Sea Lamprey
Match: ENSPMAT00000010500.1 (pep scaffold:Pmarinus_7.0:GL477503:21958:35427:1 gene:ENSPMAG00000009511.1 transcript:ENSPMAT00000010500.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 355.14 bits (910), Expect = 8.536e-112 Identity = 165/263 (62.74%), Postives = 209/263 (79.47%), Query Frame = 2 Query: 4571 SFKALPYVCLLIAMLFFIYSIIGMQVFGNIKLISEYQINRHNNFQTFTNGLLLLFRCATGESWQEIMLACDNNKPCEKDIENTNNFDCGSNFTYIYFVSFIFLCSFLMLNLFVAVIMDNFDYLTRDSSILGPHHLDEYIRVWAEYDPGAIGRIHHSEMYEMLRNMEPPVGFGKKCPYRLAYRKLIRMNMPVDENGTVNFTTTLFALIRESLNIKMSTAEYMDIK-DMELRQTICKMWPVQAKKKLNLIVPPDSELVFHKMTVG 5356 S +ALPYVCLLIAMLFFIY+I+GMQVFGN+KL E I HNNFQTF L+LLFR ATGE+WQEIML+C + KPCE+ N N CGS+F Y YFVSFIFLCSFLMLNLFVAVIMDNF+YLTRDSSILGPHHLDE++R+W +YDP A GRI +++MYE+LR+M PP+G GKKCP R+AY++L+RM+MP+ E+ TV+FTTTL ALIR +L+IK++ A + D ELR+ + +WP ++K L+++VPP + +TVG Sbjct: 1 SLQALPYVCLLIAMLFFIYAIVGMQVFGNVKLDDEGGITEHNNFQTFFQALMLLFRSATGEAWQEIMLSCLSKKPCEQHSLNGENV-CGSDFAYFYFVSFIFLCSFLMLNLFVAVIMDNFEYLTRDSSILGPHHLDEFVRIWGDYDPAATGRITYTKMYELLRHMSPPLGLGKKCPVRIAYKRLVRMDMPIAEDNTVHFTTTLMALIRTALDIKIAKAGADKFECDSELRKEMMAIWPTLSQKTLDILVPPHRAV---DLTVG 259 HSP 2 Score: 49.6766 bits (117), Expect = 3.858e-6 Identity = 32/96 (33.33%), Postives = 52/96 (54.17%), Query Frame = 2 Query: 2447 GMQLFGGEFNFEEGKPPQ--NFDTFVKALLTVFQILTGEDWNTVMYNGIQSK-------GGVKERGTVFS-IYFVLLVVFGNYTLLNVFLAIAVDN 2704 GMQ+FG +EG + NF TF +AL+ +F+ TGE W +M + + K G G+ F+ YFV + ++ +LN+F+A+ +DN Sbjct: 23 GMQVFGNVKLDDEGGITEHNNFQTFFQALMLLFRSATGEAWQEIMLSCLSKKPCEQHSLNGENVCGSDFAYFYFVSFIFLCSFLMLNLFVAVIMDN 118
BLAST of Voltage dependent L type calcium channel subunit vs. Ensembl Sea Lamprey
Match: ENSPMAT00000005302.1 (pep scaffold:Pmarinus_7.0:GL483978:134:5921:-1 gene:ENSPMAG00000004828.1 transcript:ENSPMAT00000005302.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 330.487 bits (846), Expect = 1.536e-102 Identity = 157/266 (59.02%), Postives = 199/266 (74.81%), Query Frame = 2 Query: 4529 QGYTIRILLWTFIQSFKALPYVCLLIAMLFFIYSIIGMQVFGNIKLISEYQINRHNNFQTFTNGLLLLFRCATGESWQEIMLACDNNKPCEKDIENT--NNFDCGSNFTYIYFVSFIFLCSFLMLNLFVAVIMDNFDYLTRDSSILGPHHLDEYIRVWAEYDPGAIGRIHHSEMYEMLRNMEPPVGFGKKCPYRLAYRKLIRMNMPVDENGTVNFTTTLFALIRESLNIKMSTAEYMDIKDMELRQTICKMWPVQAKKKLNLIVPP 5320 +G IR LLWTFI+SF+ALPYV LLI MLFFIY++IGMQ+FG I + QINR+NNFQTF +LLLFRCATGE+WQ+IMLAC + C+ D + + F CGS+F YFVSF LC+FL++NLFVAVIMDNFDYLTRD SILGPHHLDE+ R+WAEYDP A GRI H ++ +LR ++PP+GFGK CP+R+A ++L+ MNMP++ +GTV F TLFAL+R SL IK T ++ + ELR I K+W K L+ +VPP Sbjct: 36 RGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQMFGKIAMQDGSQINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGRRCDPDADASVGEEFSCGSSFAIFYFVSFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHVDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTSLKIK--TDGNLEQANEELRAVIKKIWKRTNMKLLDQVVPP 299
BLAST of Voltage dependent L type calcium channel subunit vs. Ensembl Sea Lamprey
Match: ENSPMAT00000008632.1 (pep scaffold:Pmarinus_7.0:GL481395:151307:166184:-1 gene:ENSPMAG00000007818.1 transcript:ENSPMAT00000008632.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 330.872 bits (847), Expect = 2.556e-99 Identity = 239/522 (45.79%), Postives = 319/522 (61.11%), Query Frame = 2 Query: 1994 RRLVKSQPFYWAVIILVFFNTVCVAIEHYEQGKWLTLFLNYAEYVFLCLFMMEMMIKMYGLSIRVYFQSSFNIFDCVVIAGSLFEIIYGIFVQDSSFGLSVLRALRLLRIFKVTRYWAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXGMQLFGGEFNFEEGKPPQ-NFDTFVKALLTVF-QILTGEDWNTVMYNGIQSKGGVKERGTVFSIYFVLLVVFGNYTLLNVFLAIAVDNLANXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSSDNFIGRLPLSIDPPMVQVCPPSPQTANSLISKNFSFDHNQVEVNDKGCLLNTNKPNGKLGMLGHDNTNFNSLESDPVPNKIEPETIQRK--PVLPYSAMFIFSPLNSLRRFCHFVVNLRYFDLFIMIVICASSIALAAEDPVKEKSLKNNILEFFDYAFTGVFTVEMILKIIDLGIILHPGSYCRDLWNILDATVVICALVAFIMGQKPSPTGNKLRGSSAKNLNTIKSLRVLRVLRPLKTINRVPKLK 3547 R VKS FYW VI+LVF NT+ +A EHY+Q +WLT + A V L LF +EM++K+Y L ++ YF S FN FDC V+ G + E I S G+SVLR +RLLRIFK TRYW SL NLV SLLNSMRSI SLL LLFLFI+IF+LLGMQLFGG+FNF+E + + +FD F ALLTVF QILTGEDWN+VMY+GI++ GG G + IYF++L + GNY LLNVFLAIAVDNLA+A+ LT+A+ E E +R A E + N P +V VC + K D + + +K + P + G D+ + + P P ++ I+ K P+ SA F+FS N R CH ++N F I++ I SS++LAAEDP++ S +N IL +FDYAFT +FT+E++LK+ G +H GS+CR +N+LD VV +L++F ++ SSA ++ +K LRVLRVLRPL+ INR LK Sbjct: 54 RAAVKSTAFYWMVIVLVFLNTLTIASEHYDQMQWLTHVQDTANKVLLALFTLEMLVKIYSLGLQAYFVSLFNRFDCFVVCGGIVETILVELKVMSPLGISVLRCVRLLRIFKATRYWNSLSNLVASLLNSMRSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDETQVRRSSFDNFPTALLTVFQQILTGEDWNSVMYDGIRAYGGPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQREAEEEKERKKIARITPRERVWNGN----------PGLVSVCVS--------VWKIPLDDPDGEDDKEKDPYPPSEYPGWRRHDTGDDDESEPEVPMGPRPRRLSELQIKEKVVPMPESSAFFLFSHTNPFRILCHHIINHTIFTNLILVFIMLSSVSLAAEDPIRSTSFRNEILGYFDYAFTTIFTIEIMLKMTAYGAFVHKGSFCRSYFNLLDLLVVGVSLISF-----------GIQWSSA--ISVVKILRVLRVLRPLRAINRAKGLK 544 HSP 2 Score: 72.4034 bits (176), Expect = 6.804e-13 Identity = 129/554 (23.29%), Postives = 222/554 (40.07%), Query Frame = 2 Query: 770 FEYMVLLTILANCIVLSMERHLPKKDKTLLAGQLELTEKYFLGIFCVEALLKIVALGFCCHKEAYLRNVWNIMDFVVVVTGFLMMFLNIDNHSDSSTVDLRTLRAVRVLRPLKLVAGFPSLQVVLKSIIRAMAPLLQIGLLVLFAITIFAIIGLEFYSGAFHYTCFKANSDKLPLPIPTEKSLVPCSNSKNGSGLGAYTCPEDYQCKAYWEGPNYGITSFDNIGYAMLTVFQCI-TMEGWTDIMYHTNDAIGN-----RFNWLYFVPLIILGSFFMLNLVLGVL------SGXXXXXXXXXXXXXXXLKLRRQQQTEKEFNGYMEWIQKAEEVLLNEATTTSEDKMRIIAARRRAEKQKYKLLGKNQSIPDFEYEDTELYSETKSMKGNIFIRSYAGIRRRR------KERCTSFWRTEKHFRFS--------VRRLVKSQPFYWAVIILVFFNTVCVAIEH-YEQGKWLTLFLNYAEYVFLCLFMMEMMIKM--YGLSIR--VYFQSSFNIFDCVVIAGSLFEIIYGIFVQDSSFGLSVLRALRLLRIFKVTR 2338 F +MV++ + N + ++ E + L + K L +F +E L+KI +LG +AY +++N D VV G + L S + + LR VR+LR K + SL ++ S++ +M + + LL+ I IF+++G++ + G F++ ++ Q + +SFDN A+LTVFQ I T E W +MY A G +YF+ L I G++ +LN+ L + + + E+ + K+ R E+ +NG + V +I E K K P + DT E++ G R RR KE+ + F FS ++ F +++ + ++V +A E + L Y +Y F +F +E+M+KM YG + + +S FN+ D +V+ SL I +GI Q SS +SV++ LR+LR+ + R Sbjct: 62 FYWMVIVLVFLNTLTIASEHY---DQMQWLTHVQDTANKVLLALFTLEMLVKIYSLGL----QAYFVSLFNRFDCFVVCGGIVETILV--ELKVMSPLGISVLRCVRLLRIFKATRYWNSLSNLVASLLNSMRSIASLLLLLFLFIIIFSLLGMQLFGGKFNF--------------------------------------DETQVRR---------SSFDNFPTALLTVFQQILTGEDWNSVMYDGIRAYGGPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQREAEEEKERKKIARITPRERVWNGNPGLVSVCVSV------------WKIPLDDPDGEDDKEKDPYPPSEYPGWRRHDTGDDDESEP-------EVPMGPRPRRLSELQIKEKVVPMPESSAFFLFSHTNPFRILCHHIINHTIFTNLILVFIMLSSVSLAAEDPIRSTSFRNEILGYFDYAFTTIFTIEIMLKMTAYGAFVHKGSFCRSYFNLLDLLVVGVSL--ISFGI--QWSS-AISVVKILRVLRVLRPLR 535 HSP 3 Score: 63.5438 bits (153), Expect = 3.875e-10 Identity = 72/264 (27.27%), Postives = 129/264 (48.86%), Query Frame = 2 Query: 4145 VVSTPFEYFIMVMIALNTLILMMKYYREEKKASSAATHDREQQAYLNYCNTLIFLNSAFTVMFSIECVLKIMAFGPKNYFRDPWNIFDFITVIGSITDVLVSELQDXXXXXXXXXXXXXXXXXXXXXXQGYTIRILLWTFIQSFKALPYVCLLIAMLFFIYSIIGMQVFGNIKLISEYQINRHNNFQTFTNGLLLLF-RCATGESWQEIMLACDNNKPCEKDIENTNNFDCGSNFTYIYFVSFIFLC-SFLMLNLFVAVIMDNF 4930 V ST F + ++V++ LNTL + ++Y +Q +L + N +F++E ++KI + G + YF +N FD V G I + ++ EL+ S L + LR R R+ K R ++ L+ + + S +++ + LL+ + I+S++GMQ+FG E Q+ R ++F F LL +F + TGE W +M I IYF+ +F+C ++++LN+F+A+ +DN Sbjct: 57 VKSTAFYWMVIVLVFLNTLTIASEHY--------------DQMQWLTHVQDTA--NKVLLALFTLEMLVKIYSLGLQAYFVSLFNRFDCFVVCGGIVETILVELKVMSPLGISVLRCVRLLRIFKATRYWNSLSNLVASLLNSMRSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDETQV-RRSSFDNFPTALLTVFQQILTGEDWNSVMY---------DGIRAYGGPSFPGMLVCIYFI-ILFICGNYILLNVFLAIAVDNL 293 HSP 4 Score: 58.151 bits (139), Expect = 2.157e-8 Identity = 43/140 (30.71%), Postives = 71/140 (50.71%), Query Frame = 2 Query: 695 SKSLFIFSEENVIRKYAKIIIEWGPFEYMVLLTILANCIVLSMERHLPKKDKTLLAGQLELTEKYFLGIFCVEALLKIVALGFCCHKEAYLRNVWNIMDFVVVVTGFLMMFLNIDNHSDSSTVDLRTLRAVRVLRPLKLV 1114 S + F+FS N R II F ++L+ I+ + + L+ E P + + L + F IF +E +LK+ A G HK ++ R+ +N++D +VV G ++ I S S V + LR +RVLRPL+ + Sbjct: 404 SSAFFLFSHTNPFRILCHHIINHTIFTNLILVFIMLSSVSLAAED--PIRSTSFRNEILGYFDYAFTTIFTIEIMLKMTAYGAFVHKGSFCRSYFNLLDLLVV--GVSLISFGIQWSSAISVV--KILRVLRVLRPLRAI 537
BLAST of Voltage dependent L type calcium channel subunit vs. Ensembl Sea Lamprey
Match: ENSPMAT00000008630.1 (pep scaffold:Pmarinus_7.0:GL481395:151307:166184:-1 gene:ENSPMAG00000007818.1 transcript:ENSPMAT00000008630.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 330.487 bits (846), Expect = 5.602e-99 Identity = 239/522 (45.79%), Postives = 319/522 (61.11%), Query Frame = 2 Query: 1994 RRLVKSQPFYWAVIILVFFNTVCVAIEHYEQGKWLTLFLNYAEYVFLCLFMMEMMIKMYGLSIRVYFQSSFNIFDCVVIAGSLFEIIYGIFVQDSSFGLSVLRALRLLRIFKVTRYWAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXGMQLFGGEFNFEEGKPPQ-NFDTFVKALLTVF-QILTGEDWNTVMYNGIQSKGGVKERGTVFSIYFVLLVVFGNYTLLNVFLAIAVDNLANXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSSDNFIGRLPLSIDPPMVQVCPPSPQTANSLISKNFSFDHNQVEVNDKGCLLNTNKPNGKLGMLGHDNTNFNSLESDPVPNKIEPETIQRK--PVLPYSAMFIFSPLNSLRRFCHFVVNLRYFDLFIMIVICASSIALAAEDPVKEKSLKNNILEFFDYAFTGVFTVEMILKIIDLGIILHPGSYCRDLWNILDATVVICALVAFIMGQKPSPTGNKLRGSSAKNLNTIKSLRVLRVLRPLKTINRVPKLK 3547 R VKS FYW VI+LVF NT+ +A EHY+Q +WLT + A V L LF +EM++K+Y L ++ YF S FN FDC V+ G + E I S G+SVLR +RLLRIFK TRYW SL NLV SLLNSMRSI SLL LLFLFI+IF+LLGMQLFGG+FNF+E + + +FD F ALLTVF QILTGEDWN+VMY+GI++ GG G + IYF++L + GNY LLNVFLAIAVDNLA+A+ LT+A+ E E +R A E + N P +V VC + K D + + +K + P + G D+ + + P P ++ I+ K P+ SA F+FS N R CH ++N F I++ I SS++LAAEDP++ S +N IL +FDYAFT +FT+E++LK+ G +H GS+CR +N+LD VV +L++F ++ SSA ++ +K LRVLRVLRPL+ INR LK Sbjct: 74 RAAVKSTAFYWMVIVLVFLNTLTIASEHYDQMQWLTHVQDTANKVLLALFTLEMLVKIYSLGLQAYFVSLFNRFDCFVVCGGIVETILVELKVMSPLGISVLRCVRLLRIFKATRYWNSLSNLVASLLNSMRSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDETQVRRSSFDNFPTALLTVFQQILTGEDWNSVMYDGIRAYGGPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQREAEEEKERKKIARITPRERVWNGN----------PGLVSVCVS--------VWKIPLDDPDGEDDKEKDPYPPSEYPGWRRHDTGDDDESEPEVPMGPRPRRLSELQIKEKVVPMPESSAFFLFSHTNPFRILCHHIINHTIFTNLILVFIMLSSVSLAAEDPIRSTSFRNEILGYFDYAFTTIFTIEIMLKMTAYGAFVHKGSFCRSYFNLLDLLVVGVSLISF-----------GIQWSSA--ISVVKILRVLRVLRPLRAINRAKGLK 564 HSP 2 Score: 73.1738 bits (178), Expect = 4.173e-13 Identity = 129/554 (23.29%), Postives = 222/554 (40.07%), Query Frame = 2 Query: 770 FEYMVLLTILANCIVLSMERHLPKKDKTLLAGQLELTEKYFLGIFCVEALLKIVALGFCCHKEAYLRNVWNIMDFVVVVTGFLMMFLNIDNHSDSSTVDLRTLRAVRVLRPLKLVAGFPSLQVVLKSIIRAMAPLLQIGLLVLFAITIFAIIGLEFYSGAFHYTCFKANSDKLPLPIPTEKSLVPCSNSKNGSGLGAYTCPEDYQCKAYWEGPNYGITSFDNIGYAMLTVFQCI-TMEGWTDIMYHTNDAIGN-----RFNWLYFVPLIILGSFFMLNLVLGVL------SGXXXXXXXXXXXXXXXLKLRRQQQTEKEFNGYMEWIQKAEEVLLNEATTTSEDKMRIIAARRRAEKQKYKLLGKNQSIPDFEYEDTELYSETKSMKGNIFIRSYAGIRRRR------KERCTSFWRTEKHFRFS--------VRRLVKSQPFYWAVIILVFFNTVCVAIEH-YEQGKWLTLFLNYAEYVFLCLFMMEMMIKM--YGLSIR--VYFQSSFNIFDCVVIAGSLFEIIYGIFVQDSSFGLSVLRALRLLRIFKVTR 2338 F +MV++ + N + ++ E + L + K L +F +E L+KI +LG +AY +++N D VV G + L S + + LR VR+LR K + SL ++ S++ +M + + LL+ I IF+++G++ + G F++ ++ Q + +SFDN A+LTVFQ I T E W +MY A G +YF+ L I G++ +LN+ L + + + E+ + K+ R E+ +NG + V +I E K K P + DT E++ G R RR KE+ + F FS ++ F +++ + ++V +A E + L Y +Y F +F +E+M+KM YG + + +S FN+ D +V+ SL I +GI Q SS +SV++ LR+LR+ + R Sbjct: 82 FYWMVIVLVFLNTLTIASEHY---DQMQWLTHVQDTANKVLLALFTLEMLVKIYSLGL----QAYFVSLFNRFDCFVVCGGIVETILV--ELKVMSPLGISVLRCVRLLRIFKATRYWNSLSNLVASLLNSMRSIASLLLLLFLFIIIFSLLGMQLFGGKFNF--------------------------------------DETQVRR---------SSFDNFPTALLTVFQQILTGEDWNSVMYDGIRAYGGPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQREAEEEKERKKIARITPRERVWNGNPGLVSVCVSV------------WKIPLDDPDGEDDKEKDPYPPSEYPGWRRHDTGDDDESEP-------EVPMGPRPRRLSELQIKEKVVPMPESSAFFLFSHTNPFRILCHHIINHTIFTNLILVFIMLSSVSLAAEDPIRSTSFRNEILGYFDYAFTTIFTIEIMLKMTAYGAFVHKGSFCRSYFNLLDLLVVGVSL--ISFGI--QWSS-AISVVKILRVLRVLRPLR 555 HSP 3 Score: 63.5438 bits (153), Expect = 4.287e-10 Identity = 72/264 (27.27%), Postives = 129/264 (48.86%), Query Frame = 2 Query: 4145 VVSTPFEYFIMVMIALNTLILMMKYYREEKKASSAATHDREQQAYLNYCNTLIFLNSAFTVMFSIECVLKIMAFGPKNYFRDPWNIFDFITVIGSITDVLVSELQDXXXXXXXXXXXXXXXXXXXXXXQGYTIRILLWTFIQSFKALPYVCLLIAMLFFIYSIIGMQVFGNIKLISEYQINRHNNFQTFTNGLLLLF-RCATGESWQEIMLACDNNKPCEKDIENTNNFDCGSNFTYIYFVSFIFLC-SFLMLNLFVAVIMDNF 4930 V ST F + ++V++ LNTL + ++Y +Q +L + N +F++E ++KI + G + YF +N FD V G I + ++ EL+ S L + LR R R+ K R ++ L+ + + S +++ + LL+ + I+S++GMQ+FG E Q+ R ++F F LL +F + TGE W +M I IYF+ +F+C ++++LN+F+A+ +DN Sbjct: 77 VKSTAFYWMVIVLVFLNTLTIASEHY--------------DQMQWLTHVQDTA--NKVLLALFTLEMLVKIYSLGLQAYFVSLFNRFDCFVVCGGIVETILVELKVMSPLGISVLRCVRLLRIFKATRYWNSLSNLVASLLNSMRSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDETQV-RRSSFDNFPTALLTVFQQILTGEDWNSVMY---------DGIRAYGGPSFPGMLVCIYFI-ILFICGNYILLNVFLAIAVDNL 313 HSP 4 Score: 57.7658 bits (138), Expect = 2.371e-8 Identity = 43/140 (30.71%), Postives = 71/140 (50.71%), Query Frame = 2 Query: 695 SKSLFIFSEENVIRKYAKIIIEWGPFEYMVLLTILANCIVLSMERHLPKKDKTLLAGQLELTEKYFLGIFCVEALLKIVALGFCCHKEAYLRNVWNIMDFVVVVTGFLMMFLNIDNHSDSSTVDLRTLRAVRVLRPLKLV 1114 S + F+FS N R II F ++L+ I+ + + L+ E P + + L + F IF +E +LK+ A G HK ++ R+ +N++D +VV G ++ I S S V + LR +RVLRPL+ + Sbjct: 424 SSAFFLFSHTNPFRILCHHIINHTIFTNLILVFIMLSSVSLAAED--PIRSTSFRNEILGYFDYAFTTIFTIEIMLKMTAYGAFVHKGSFCRSYFNLLDLLVV--GVSLISFGIQWSSAISVV--KILRVLRVLRPLRAI 557
BLAST of Voltage dependent L type calcium channel subunit vs. Ensembl Sea Lamprey
Match: ENSPMAT00000003253.1 (pep scaffold:Pmarinus_7.0:GL478330:685:47673:1 gene:ENSPMAG00000002915.1 transcript:ENSPMAT00000003253.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 317.39 bits (812), Expect = 6.418e-91 Identity = 219/379 (57.78%), Postives = 265/379 (69.92%), Query Frame = 2 Query: 1655 LKLRRQQQTEKEFNGYMEWIQKAEEVLLNEATTTSEDKMRI-----------------IAAR-------RRA--EKQKYKLLGKNQSIPDFEYEDTELYSETKSMKGNIFIRSYAGIRRRRKERCTSFWRTEKHFRFSVRRLVKSQPFYWAVIILVFFNTVCVAIEHYEQGKWLTLFLNYAEYVFLCLFMMEMMIKMYGLSIRVYFQSSFNIFDCVVIAGSLFEIIYGIFVQDSSFGLSVLRALRLLRIFKVTRYWAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXGMQLFGGEFNFEEGKPPQNFDTFVKALLTVFQILTGEDWNTVMYNGIQSKGGVKERGTVFSIYFVLLVVFGNYTLLNVFLAIAVDNLAN 2713 LKLRRQQQ E+E NGYMEWI KAEEV+L E +EDK +++R RRA +K + L+ + + E +S+ S G+ F R A I ++E + F R EK RF +RR+VKS FYW V+ LV NT+CVAI HY+Q LT L YAE+VFL LF+ EM++KMYGL R YF SSFN FD VI GS+FEII+ +SFG+ VLRALRLLRIFKVT+YWASLRNLV+SLLNSM+SIISLLFLLFLFI++FALLGMQLFGG+FNFEE PP NFDTF A++TVFQILTGEDWN VMY+ I+S+GG+ RGT+F IYF++L +FGNYTLLNVFLAIAVDNLAN Sbjct: 20 LKLRRQQQIERELNGYMEWICKAEEVMLAEEDRNAEDKSAFDGEEITSGNPPPNSRPPLSSRWLNVTVLRRATLKKSRTDLIQAEEGL-------NERFSDITST-GSPFAR--ASIVSVKQETSSYFQRKEKRMRFFIRRMVKSHTFYWTVLCLVGLNTLCVAIVHYDQPVLLTDLLTYAEFVFLGLFLSEMLLKMYGLGTRSYFHSSFNCFDFGVIIGSIFEIIWATIQPGTSFGIRVLRALRLLRIFKVTKYWASLRNLVVSLLNSMKSIISLLFLLFLFIVVFALLGMQLFGGQFNFEECTPPTNFDTFPAAIMTVFQILTGEDWNVVMYDAIKSQGGIN-RGTIFCIYFIVLTLFGNYTLLNVFLAIAVDNLAN 387 HSP 2 Score: 158.303 bits (399), Expect = 4.087e-39 Identity = 72/116 (62.07%), Postives = 91/116 (78.45%), Query Frame = 2 Query: 3065 QRKPVLPYSAMFIFSPLNSLRRFCHFVVNLRYFDLFIMIVICASSIALAAEDPVKEKSLKNNILEFFDYAFTGVFTVEMILKIIDLGIILHPGSYCRDLWNILDATVVICALVAFI 3412 + KP+LPYS+MFIFS N LRR CH++V LRYF++ I++VI SSIALAAEDPV+ S N IL FDY FTGVFT E+ +K+IDLG++ HPG+Y RDLWNILD VV AL+A++ Sbjct: 796 RHKPILPYSSMFIFSSTNPLRRLCHYIVTLRYFEMCILLVIAMSSIALAAEDPVEADSPWNKILRNFDYVFTGVFTFELFIKMIDLGLVFHPGAYFRDLWNILDFIVVSGALMAYV 911 HSP 3 Score: 80.1073 bits (196), Expect = 5.267e-15 Identity = 68/278 (24.46%), Postives = 136/278 (48.92%), Query Frame = 2 Query: 4097 YMPKDKTTIKYRVWRLVVSTPFEYFIMVMIALNTLILMMKYYREEKKASSAATHDREQQAYLNYCNTLIFLNSAFTVMFSIECVLKIMAFGPKNYFRDPWNIFDFITVIGSITDVLVSELQDXXXXXXXXXXXXXXXXXXXXXXQGYTIRILLWTFIQSFKALPYVCLLIAMLFFIYSIIGMQVFGNIKLISEYQINRHNNFQTFTNGLLLLFRCATGESWQEIMLACDNNKPCEKDIENTNNFDCGSNFTYIYFVSFIFLCSFLMLNLFVAVIMDNF 4930 Y + + +++ + R+V S F + ++ ++ LNTL + + +Y +Q L + L + F +F E +LK+ G ++YF +N FDF +IGSI +++ + +Q + + LR R R+ K+ + ++R L+ + + S K++ + L+ + +++++GMQ+FG E NF TF ++ +F+ TGE W +M I++ + G+ F IYF+ ++ +LN+F+A+ +DN Sbjct: 136 YFQRKEKRMRFFIRRMVKSHTFYWTVLCLVGLNTLCVAIVHY--------------DQPVLL--TDLLTYAEFVFLGLFLSEMLLKMYGLGTRSYFHSSFNCFDFGVIIGSIFEIIWATIQPGTSFGIRVLRALRLLRIFKVTKYWASLRNLVVSLLNSMKSIISLLFLLFLFIVVFALLGMQLFGGQFNFEE--CTPPTNFDTFPAAIMTVFQILTGEDWNVVMYDA---------IKSQGGINRGTIFC-IYFIVLTLFGNYTLLNVFLAIAVDNL 385 HSP 4 Score: 65.855 bits (159), Expect = 1.032e-10 Identity = 39/110 (35.45%), Postives = 60/110 (54.55%), Query Frame = 2 Query: 701 SLFIFSEENVIRKYAKIIIEWGPFEYMVLLTILANCIVLSMERHLPKKDKTLLAGQLELTEKYFLGIFCVEALLKIVALGFCCHKEAYLRNVWNIMDFVVVVTGFLMMFL 1030 S+FIFS N +R+ I+ FE +LL I + I L+ E P + + L + F G+F E +K++ LG H AY R++WNI+DF +VV+G LM ++ Sbjct: 805 SMFIFSSTNPLRRLCHYIVTLRYFEMCILLVIAMSSIALAAED--PVEADSPWNKILRNFDYVFTGVFTFELFIKMIDLGLVFHPGAYFRDLWNILDF-IVVSGALMAYV 911 HSP 5 Score: 50.0618 bits (118), Expect = 6.806e-6 Identity = 72/305 (23.61%), Postives = 137/305 (44.92%), Query Frame = 2 Query: 701 SLFIFSEENVIRKYAKIIIEWGPFEYMVLLTILANCIVLSMERHLPKKDKTLLAGQLELTEKYFLGIFCVEALLKIVALGFCCHKEAYLRNVWNIMDFVVVVTG-FLMMFLNIDNHSDSSTVDLRTLRAVRVLRPLKLVAGFPSLQVVLKSIIRAMAPLLQIGLLVLFAITIFAIIGLEFYSGAFHYTCFKANSDKLPLPIPTEKSLVPCSNSKNGSGLGAYTCPEDYQCKAYWEGPNYGITSFDNIGYAMLTVFQCITMEGWTDIMYHTNDAIG--NRFN--WLYFVPLIILGSFFMLNLVLGV 1600 S + +E +R + + +++ F + VL + N + +++ + LL L E FLG+F E LLK+ LG +Y + +N DF V++ F +++ I ++ +R LRA+R+LR K+ + SL+ ++ S++ +M ++ + L+ I +FA++G++ + G F++ E+ P T+FD A++TVFQ +T E W +MY + G NR +YF+ L + G++ +LN+ L + Sbjct: 134 SSYFQRKEKRMRFFIRRMVKSHTFYWTVLCLVGLNTLCVAIVHY---DQPVLLTDLLTYAEFVFLGLFLSEMLLKMYGLG----TRSYFHSSFNCFDFGVIIGSIFEIIWATI---QPGTSFGIRVLRALRLLRIFKVTKYWASLRNLVVSLLNSMKSIISLLFLLFLFIVVFALLGMQLFGGQFNF----------------EECTPP--------------------------------TNFDTFPAAIMTVFQILTGEDWNVVMYDAIKSQGGINRGTIFCIYFIVLTLFGNYTLLNVFLAI 380
BLAST of Voltage dependent L type calcium channel subunit vs. Ensembl Yeast
Match: CCH1 (Voltage-gated high-affinity calcium channel; involved in calcium influx in response to some environmental stresses as well as exposure to mating pheromones; interacts and partially co-localizes with Mid1p; however, evidence suggests CCH1 is not required for Mid1p function [Source:SGD;Acc:S000003449]) HSP 1 Score: 159.073 bits (401), Expect = 4.486e-39 Identity = 192/824 (23.30%), Postives = 333/824 (40.41%), Query Frame = 2 Query: 2912 FDHNQVEVNDKGCLLNTNKPNGKLGMLGHDNTNFNSLESDPVPNKIEPETIQRKPVLPYSAMFIFSPLNSLRRFCHFVV---------NLRYF------------------DLFIMIVICASSIALAAEDPV------KEKSLKNNILEFFDYAFTGVFTVEMILKIIDLGIILHPGSYCRDLWNILDATVVICALVAFIMGQKPSPTGNKLRGSSAKNLNTIKSLRVLRVLRPLKTINRVPKLKAVFDCVV-SSLKNVFNILIVYILFQFIFAVIAVQLFQGKFFYCNDASKSSRETCRGYFFDYAGRSTPETKKRLWQHHDFHFDNILYAMLTLFTVTTGEGWPTVLKNSMESTNIDNGPIADYRQEMAXXXXXXXXXXXXXXXXXXXALIIITFQEQGENELIDLDLD---KNQKQCID---FAINEKP-------LCRYMPK------DKTTIKYRVWRLVVSTP---FEYFIMVMIALNTLILMMKYYREEKKASSAATHDREQQAYLNYCNTLIFLNSAFTVMFSIECVLKIMAFGPKNYFRDPWNIFDF-ITVIGSITDVLVSELQDXXXXXXXXXXXXXXXXXXXXXXQGYTIRILLWTFIQSFKALPYVCLLIAMLFFIYSIIGMQVFGNIKLISEYQINRHNNFQTFTNGLLLLFRCATGESWQEIMLACDNNKP-CEKDIENTNNFDCGS-NFTYIYFVSFIFLCSFLMLNLFVAVIMDNFDYLTRDS---SILGPHHLDEYIRVWAEYDPGAIGRIHHSEMYEMLRNMEPPVGFGKKCPYRLAYRKLIRMNMPVDENGTVNFTTTLFALIRE 5197 F +N N TN NG+ +L N E + + + +++ P+ YS F FSP + RRFC +V R+F D+F+ I A+ + + V K N D AF G F++E I+K + G I P +Y R+ WN +D V+I + I K + GN R K L LR LR L N + F+ V+ L +F ++ + F F V + +F+G+ CND S R C + + + + R++Q H D+ A +L+ + + EGW +L+N M S+ I + AL ++ F +++L + NQ + F I EK L + PK + + ++ ++L V + F+ V++ L+ ++L+ + Y Q Y + ++ F I+ L + GP+ YFR WN I +I I + + + S + F + ++ Q T+ LL T + S + + +LF +Y+I Q+FG +L S N NF+T +++LFRC+ GE W IM ++P C D +N+ DCGS + Y+ +S+ + ++ +N+FV++I+ NF Y+ R S + + +YI W+++D G + S + ++ + + P+ F K RL + L+ M V+ + + L L +E Sbjct: 1107 FANNPFYKNSDVVFTETNDINGRTYIL-----ELNEYEDEKL------DYLKKYPLFNYSYYF-FSPQHRFRRFCQRLVPPSTGKRTDGSRFFEDSTDLYNKRSYFHHIERDVFVFIFALATILLIVCSCYVTPLYRMHHKMGTWNWSSALDCAFIGAFSIEFIVKTVADGFIYSPNAYLRNPWNFIDFCVLISMWINLIAYLKNN--GNLSR--------IFKGLTALRALRCLTISNTA---RQTFNLVMFDGLNKIFEAGLISLSLLFPFTVWGLSIFKGRLGTCNDGSL-GRADCYNEYSNSVFQWDIMS-PRVYQQPYLHLDSFASAFSSLYQIISLEGWVDLLENMMNSSGIGTPATV--------------------MGSAGNALFLVLFNFLSMVFILNLFVSFIVNNQARTTGSAYFTIEEKAWLESQKLLSQAKPKAIPNLIELSRVRQFFYQLAVEKKNFYYASFLQVVLYLHIIMLLSRSYNPGNLIGY-------QGVYFMFSTSV----------FLIQEALHMCGEGPRLYFRQKWNSIRLSIIIIAFIMNAVAFHVPASHYWFHNIKGFFLLVIFLFIIPQNDTLTELLETAMASLPPILSLTYTWGVLFLVYAIALNQIFGLTRLGSNTTDNI--NFRTVIKSMIVLFRCSFGEGWNYIMADLTVSEPYCSSD-DNSTYTDCGSETYAYLLLMSWNIISMYIFVNMFVSLIIGNFSYVYRSGGSRSGINRSEIKKYIEAWSKFDTDGTGELELSYLPRIMHSFDGPLSF-KIWEGRLTIKSLVENYMEVNPDDPYDVKIDLIGLNKE 1862 HSP 2 Score: 80.8777 bits (198), Expect = 2.300e-15 Identity = 60/231 (25.97%), Postives = 113/231 (48.92%), Query Frame = 2 Query: 959 AYLRNVWNIMDFVVVVTGFLMMFLNIDNHSDSSTVDL-RTLRAVRVLRPLKLVAGFPSLQVVLKSIIRAMAPLLQIGLLVLFAITIFAIIGLEFYSGAFHYTCFKANSDKLPL---------------PIPTEKSLVPCSNSKNGSGLGAYTCPEDYQCKAYWEGPNYGITSFDNIGYAMLTVFQCITMEGWTDIMYHTNDAIGNRFNWLYFVPLIILGSFFMLNLVLGVL 1603 A+ R+ WN +D V V+ +L MFL+I ++ + + + + L +R+LR + + G PS +L+ + + L+ + ++++ F I+G++ + G+F C N + P P+ K + GS + CP+ +C + P G SFDNI +M VF ++ +TD+MY+T D+ L+F+ I + + ++LNL++ VL Sbjct: 488 AFARSSWNRIDLVSSVSFWLGMFLSIKSYDTKTGIRIFKPLAILRILRLVNVDTGMPS---ILRGLKYGIPQLVNVSSMLVYFWIFFGILGVQIFQGSFRRQCVWFNPED-PTDTYQYDMQFCGGYLDPVTKRKQNYIYEDGSEGSVSKGFLCPQYSKCVSN-ANPYNGRISFDNIVNSMELVFVIMSANTFTDLMYYTMDS-DEMAACLFFIVCIFVLTIWLLNLLIAVL 712 HSP 3 Score: 71.633 bits (174), Expect = 1.514e-12 Identity = 69/293 (23.55%), Postives = 123/293 (41.98%), Query Frame = 2 Query: 770 FEYMVLLTILANCIVLSMERHLPKKDKTLLAGQLELTEKYFLGIFCVEALLKIVALGFCCHKEAYLRNVWNIMDFVVVVTGFLMMFLNIDNHSDSSTVDLRTLRAVRVLRPLKLVAGFPSLQVVLKSIIRAMAPLLQIGLLVLFAITIFAIIGLEFYSGAFHYTCFKANSDKLPLPIPTEKSLVPCSNSKNGSGLGAYTCPEDYQCKAY-WE--GPNYGITSF---DNIGYAMLTVFQCITMEGWTDIMYHTNDA---------IGNRFNWLYFVPLIILGSFFMLNLVLGVL 1603 F +L I+ +C V + R K + L+ F+G F +E ++K VA GF AYLRN WN +DF V+++ ++ + + N+ + S + + L A+R LR L + + Q + + + + GL+ L + F + GL + G TC N LG C +Y + W+ P + D+ A +++Q I++EGW D++ + ++ +G+ N L+ V L F+LNL + + Sbjct: 1212 FALATILLIVCSCYVTPLYRMHHKMGTWNWSSALDCA---FIGAFSIEFIVKTVADGFIYSPNAYLRNPWNFIDFCVLISMWINLIAYLKNNGNLSRI-FKGLTALRALRCLTISNT--ARQTFNLVMFDGLNKIFEAGLISLSLLFPFTVWGLSIFKGRLG-TC-------------------------NDGSLGRADCYNEYSNSVFQWDIMSPRVYQQPYLHLDSFASAFSSLYQIISLEGWVDLLENMMNSSGIGTPATVMGSAGNALFLVLFNFLSMVFILNLFVSFI 1472
BLAST of Voltage dependent L type calcium channel subunit vs. Ensembl Nematostella
Match: EDO46991 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RNU9]) HSP 1 Score: 702.205 bits (1811), Expect = 0.000e+0 Identity = 417/981 (42.51%), Postives = 607/981 (61.88%), Query Frame = 2 Query: 2990 LGHDNTNFNSLESDPVPNKIEPETIQRKPVLPYSAMFIFSPLNSLRRFCHFVVNLRYFDLFIMIVICASSIALAAEDPVKEKSLKNNILEFFDYAFTGVFTVEMILKIIDLGIILHPGSYCRDLWNILDATVVICALVAFIMGQKPSPTGNKLRGSSAKNLNTIKSLRVLRVLRPLKTINRVPKLKAVFDCVVSSLKNVFNILIVYILFQFIFAVIAVQLFQGKFFYCNDASKSSRETCRGYFFDYAGR--STPETKKRLWQHHDFHFDNILYAMLTLFTVTTGEGWPTVLKNSMESTNIDNGPIADYRQEMAXXXXXXXXXXXXXXXXXXXALIIITFQEQGENELIDLDLDKNQKQCIDFAINEKPLCRYMPKDKTTIKYRVWRLVVSTPFEYFIMVMIALNTLILMMKYYREEKKASSAATHDREQQAYLNYCNTLIFLNSAFTVMFSIECVLKIMAFGPKNYFRDPWNIFDFITVIGSITDVLVSELQDXXXXXXXXXXXXXXXXXXXXXXQGYTIRILLWTFIQSFKALPYVCLLIAMLFFIYSIIGMQVFGNIKLISEYQINRHNNFQTFTNGLLLLFRCATGESWQEIMLACDN--NKPCEKDI--ENTNNFDCGSNFTYIYFVSFIFLCSFLMLNLFVAVIMDNFDYLTRDSSILGPHHLDEYIRVWAEYDPGAIGRIHHSEMYEMLRNMEPPVGFGKKCPYRLAYRKLIRMNMPVDENGTVNFTTTLFALIRESLNIKMSTAE-YMDIKDMELRQTICKMWPVQAKKKLNLIV-PPDSELVFHKMTVGKIYAGYLIVENWRAYK------NSQEQGPRSSPAVSIKSVT----KPVVKEEKSANL---LAKFFVAFKSNTNKSNISLDSHHERDEERF------SIDHTYGEDY---DANRRYSYLRRG-SKPRGSKEIYSDLTPTQDYSYGLRPEHATIPGMPAPRKFGNRPRSPMYSLSELETKDRANTP 5839 L D+ + + + V + E + +P+ P S++FIFS N R CH + YF FI+++I SS LAAEDP+ S +N +L +FDY FT VFT+E+ +KII G+ILH GS+CR +N+LD VV ++V+ LR SS++ ++ ++ LRVLRVLRPL+ INR LK V CV ++K + NI++V +LF F+FAVI VQLF+G FF C DA K ++ C+G + ++ G + P K R WQ F+F+++ AMLTLFTV T EGWP +L++SM+ST++D GP + R +AI+Y+++ I+ FF +NIFV +I+TFQ +GE E D +LDKNQ++C++FA+ +P RY+P ++ +++ VWR+V S PFEY I I NT++LMM+YY E K Y L N FT +F +EC+LK+ AF PKNYF D WN+FDF+ V+GS+ D+ ++E+ + GF RLFRA RL+KLL QG I+ LLWTFI+SF+ALPYV LLI M FFIY+++GMQ+FG I + E QINR+NNFQTF L++LFR ATGE+WQ IMLAC + N C+ + ++T+ CG++F Y YF SF +CSFL++NLFVAVIMDNFDYLTRD SILGPHHLDE++RVW+EYDP A G + H ++ +L+ + PP+GFGK CP+R A ++L+ MNMP++ +GTVNF TLF L+R SL+IK + ++ + E+R I K+WP +++ L+ I+ PP + ++TVGK YA YLI E +R +K N+Q Q S+ A+ T P ++ S +L + F+ K +I S H+R E S H+ + R +++++G S P ++ S L T +S+G P + + R+ P+ + ++ E+K A+ P Sbjct: 778 LAEDSKATLNRDHESVRSATSTEVMDHEPMPPESSLFIFSNTNCFRVVCHRIATNSYFVNFILLLIIVSSCMLAAEDPLNSNSKRNQVLNYFDYFFTAVFTIEITIKIIAYGVILHKGSFCRSAFNLLDFLVVAVSIVSI-----------ALRDSSSQ-ISVVRILRVLRVLRPLRAINRAKGLKHVVQCVFVAVKTIGNIMLVTVLFNFLFAVIGVQLFKGTFFSCTDAEKITKRECQGQYIEFKGPGLTNPVVKDREWQPQTFNFNDVPQAMLTLFTVMTFEGWPGILESSMDSTDVDEGPFLNNRPWVAIYYVIYIIIIAFFMINIFVGFVIVTFQNEGEEEFKDCELDKNQRKCVEFALKARPTRRYIPTNR--LQFHVWRVVTSQPFEYLIFAFITGNTILLMMQYYNEPKL----------------YTRVLDGFNIGFTSVFLLECILKLFAFKPKNYFLDRWNLFDFVVVVGSVVDITMNEVSSEQMFAFGFFRLFRALRLVKLLNQGSGIKTLLWTFIKSFQALPYVGLLIIMTFFIYAVVGMQMFGRIAIDPETQINRNNNFQTFPQSLMVLFRSATGENWQLIMLACTDTPNAKCDPNAYPQDTDGL-CGTDFAYAYFCSFYAICSFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFVRVWSEYDPEASGCVKHVDIVTVLKRIAPPLGFGKFCPHREACKRLVSMNMPLNRDGTVNFNATLFGLVRTSLSIKRPEGKGSLEKANEEMRAIIMKVWPKTSQEFLDEIIQPPGGD---DEVTVGKFYATYLIQEYFRRFKARQRAENAQYQDAHSTQALQAGLRTLHGLGPQLRRAISGHLDDDDEELFL-------KEDIQQKSQHKRFWESLKNAVTPSPRHSRPSSLRRPGSIRLSAFIKKGNSTPEAQRK--SSLPATLTFSHG--------PLLTSDRQLLVPPQQSDVNANDKESKQSAHVP 1707 HSP 2 Score: 542.732 bits (1397), Expect = 1.257e-159 Identity = 331/657 (50.38%), Postives = 428/657 (65.14%), Query Frame = 2 Query: 767 PFEYMVLLTILANCIVLSMERHLPKKDKTLLAGQLELTEKYFLGIFCVEALLKIVALGFCCHKEAYLRNVWNIMDFVVVVTGFLMMFLNIDNHSDSSTVDLRTLRAVRVLRPLKLVAGFPSLQVVLKSIIRAMAPLLQIGLLVLFAITIFAIIGLEFYSGAFHYTCFKANSDKL----PLPIPTEKSLVPCSNSKNGSGLGAYTCPEDYQCKAYWEGPNYGITSFDNIGYAMLTVFQCITMEGWTDIMYHTNDAIGNRFNWLYFVPLIILGSFFMLNLVLGVLSGXXXXXXXXXXXXXXXLKLRRQQQTEKEFNGYMEWIQKAEEVLLNEATTTSEDKM--RIIAARRRAEKQKYKLLGKNQSIPDFEYEDTELYSETKSMKGNIFIRSYAGIRRRRKERCTSFWRTEKHFRFSVRRLVKSQPFYWAVIILVFFNTVCVAIEHYEQGKWLTLFLNYAEYVFLCLFMMEMMIKMYGLSIRVYFQSSFNIFDCVVIAGSLFEIIYGIFVQDSSFGLSVLRALRLLRIFKVTRYWAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXGMQLFGGEFNF-EEGKPPQNFDTFVKALLTVFQILTGEDWNTVMYNGIQSKGGVKERGTVFSI-YFVLLVVFGNYTLLNVFLAIAVDNLAN 2713 PF+ M+L+TI ANC L+ + LP++D +L+ +LE+ E FLGIF +E++LKI+A GF H AYLRN WNI+DFV+VV G + + + + D++ LRA RVLRPL+LV+G PSLQVVL SII+A+ PL I LLV+F + I+AIIG+E + G H TC+ + + P P TE CSN+ G C WEGPNYGIT+FDNIG A LTVFQCIT+EGWTD+MY NDAIGN + WLYFV LII GSFF+LNLVLGVLSGEFAKE+ R +K F KLR +Q + ++GY++WI +AE++ + + E+ R + RRR E +NQ ED+ + I R++K R R S R+ VK+Q FYW VI+ VF N++ +A+EHY Q ++LT FL+ A +FL LF +EM++KMY L YF S FN FDC+V+ SL E+ + G+S+LR +RLLRIFKVTRYW+SL NLV SLLNSMRSI+ LL LL LF++IF+LLGMQ+FGG+FN +E P NFD+F +AL+TVFQILTGEDWN VMY GIQS GG+ E + I YF+ LVV GNY LLNVFLAIAVDNLA+ Sbjct: 75 PFDVMILITIFANCAALAAFQPLPEQDSSLINEELEVAEFVFLGIFTMESVLKIIAYGFVMHPGAYLRNGWNILDFVIVVVGLATIIVKL---YTPDSFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKALIPLFHIALLVVFVVIIYAIIGVELFMGKLHSTCYDNVTGQPTFDEPHPCSTESEGYSCSNAGPGQ-----------VCLKKWEGPNYGITNFDNIGLACLTVFQCITLEGWTDVMYSINDAIGNSWPWLYFVTLIIWGSFFVLNLVLGVLSGEFAKEKARAQKSGEFQKLREKQLVDDAYHGYLDWISQAEDIEGDSSAGEDEEGKADRKPSFRRRKENDDISKNKENQ-------EDSAASDQ-------------GWIDRKKK----ILKRFHHRLRRSCRKAVKTQWFYWTVIVFVFLNSLTLALEHYNQPEFLTQFLDKANKLFLALFTLEMVVKMYCLGFHGYFASLFNRFDCLVVISSLLELGLTEAMDQRPIGISMLRCVRLLRIFKVTRYWSSLSNLVASLLNSMRSIMGLLLLLSLFMVIFSLLGMQIFGGKFNLGDEDVPRSNFDSFWRALVTVFQILTGEDWNAVMYTGIQSWGGITESLSAIPILYFIFLVVVGNYILLNVFLAIAVDNLAD 693 HSP 3 Score: 140.198 bits (352), Expect = 7.433e-33 Identity = 105/309 (33.98%), Postives = 156/309 (50.49%), Query Frame = 2 Query: 3008 NFNSLESDPVPNKIEPE-TIQRKP---VLPYSAMFIFSPLNSLRR-----FCHFVVNL--RYFDLFIMIVICASSIALAAEDPVKEK--SLKNNILEFFDYAFTGVFTVEMILKIIDLGIILHPGSYCRDLWNILDATVVICALVAFIMGQKPSPTGNKLRGSSAKNLNTIKSLRVLRVLRPLKTINRVPKLKAVFDCVVSSLKNVFNILIVYILFQFIFAVIAVQLFQGKFF---YCN-------DASKSSRETCRGYFFDYAGRSTPETKKRLWQHHDF---HFDNILYAMLTLFTVTTGEGWPTVL 3856 N L P K P+ Q+KP V P A+F + N +R F F +++ FD+ I+I I A+ ALAA P+ E+ SL N LE ++ F G+FT+E +LKII G ++HPG+Y R+ WNILD +V+ L I+ KL + + +K+LR RVLRPL+ ++ VP L+ V + ++ +L +F+I ++ + I+A+I V+LF GK Y N D GY AG KK W+ ++ +FDNI A LT+F T EGW V+ Sbjct: 14 NRAKLNGQPKYGKPPPQPKRQKKPTNAVRPKRALFCLTLGNPIRSTAISLFTVFFLDVFRTPFDVMILITIFANCAALAAFQPLPEQDSSLINEELEVAEFVFLGIFTMESVLKIIAYGFVMHPGAYLRNGWNILDFVIVVVGLATIIV---------KLYTPDSFD---VKALRAFRVLRPLRLVSGVPSLQVVLNSIIKALIPLFHIALLVVFVVIIYAIIGVELFMGKLHSTCYDNVTGQPTFDEPHPCSTESEGYSCSNAGPGQVCLKK--WEGPNYGITNFDNIGLACLTVFQCITLEGWTDVM 308 HSP 4 Score: 103.219 bits (256), Expect = 1.247e-21 Identity = 128/572 (22.38%), Postives = 243/572 (42.48%), Query Frame = 2 Query: 731 IRKYAKIIIEWGPFEYMVLLTILANCIVLSMERHLPKKDKTLLAGQLELTEKYFLGIFCVEALLKIVALGFCCHKEAYLRNVWNIMDFVVVVTGFLMMFLNIDNHSDSSTVDLRTLRAVRVLRPLKLVAGFPSLQVVLKSIIRAMAPLLQIGLLVLFAITIFAIIGLEFYSGAFHYTCFKANSDKLPLPIPTEKSLVPCSNSKNGSGLGAYTCPEDYQCKAYWEGPNYGITSFDNIGYAMLTVFQCITMEGWTDIMYHTNDAIG------NRFNWLYFVPLIILGSFFMLNLVLGVL--------SGXXXXXXXXXXXXXXXLKLRRQQQTEKEFNGYMEWIQKAEEVLLNEATTTSEDKMRIIAARRRAE------KQKYKLLGKNQSIPDFEYEDTELYSETKSMKGNIFIRSYAGIRRRRK-----------ERCTSFWRTEKHFRFSVRRLVKSQPFYWAVIILVFFNTVCVAIEH-YEQGKWLTLFLNYAEYVFLCLFMMEMMIKM--YGLSIR--VYFQSSFNIFDCVVIAGSLFEIIYGIFVQDSSFGLSVLRALRLLRIFKVTR 2338 +R+ + ++ F + V++ + N + L++E + L L+ K FL +F +E ++K+ LGF Y +++N D +VV++ L L + D + + LR VR+LR K+ + SL ++ S++ +M ++ + LL+ + IF+++G++ + G F+ LG P ++FD+ A++TVFQ +T E W +MY + G + LYF+ L+++G++ +LN+ L + S +E ++ E+ R ++ E N +E A+T+S R+I + E K + L K+ P + E L ++K+ R + +R E + FR R+ + F +++L+ ++ +A E LNY +Y F +F +E+ IK+ YG+ + + +S+FN+ D +V+A S I I ++DSS +SV+R LR+LR+ + R Sbjct: 447 LRRSCRKAVKTQWFYWTVIVFVFLNSLTLALEHY---NQPEFLTQFLDKANKLFLALFTLEMVVKMYCLGF----HGYFASLFNRFDCLVVISSLLE--LGLTEAMDQRPIGISMLRCVRLLRIFKVTRYWSSLSNLVASLLNSMRSIMGLLLLLSLFMVIFSLLGMQIFGGKFN--------------------------------LGDEDVPR---------------SNFDSFWRALVTVFQILTGEDWNAVMYTGIQSWGGITESLSAIPILYFIFLVVVGNYILLNVFLAIAVDNLADAESLTEMEEEKKKEREEELEMKLRMEEKESSSNKDLE---------NKRASTSSGKSHRLIKIWKTNELLHLAGKIRVSRLRKH---PITDAESPSLAEDSKATLN----RDHESVRSATSTEVMDHEPMPPESSLFIFSNTNCFRVVCHRIATNSYFVNFILLLIIVSSCMLAAEDPLNSNSKRNQVLNYFDYFFTAVFTIEITIKIIAYGVILHKGSFCRSAFNLLDFLVVAVS----IVSIALRDSSSQISVVRILRVLRVLRPLR 942 HSP 5 Score: 99.7525 bits (247), Expect = 1.230e-20 Identity = 83/312 (26.60%), Postives = 152/312 (48.72%), Query Frame = 2 Query: 620 SKTTSMRSLAKRTINLSFPGMQTSTS------------KSLFIFSEENVIRKYAKIIIEWGPFEYMVLLTILANCIVLSMERHLPKKDKTLLAGQLELTEKYFLGIFCVEALLKIVALGFCCHKEAYLRNVWNIMDFVVVVTGFLMMFLNIDNHSDSSTVDLRTLRAVRVLRPLKLVAGFPSLQVVLKSIIRAMAPLLQIGLLVLFAITIFAIIGLEFYSGAFHYTCFKANSDKLPLPIPTEKSLVPCSNSKNGSGLGAYTCPE-DYQCKAYWEGPNYGITSFDNIGYAMLTVFQCITMEGWTDIMYHTNDA 1516 +++ S+ +K T+N ++++TS SLFIFS N R I F +LL I+ + +L+ E L K L + +F +F +E +KI+A G HK ++ R+ +N++DF+VV + + L D+ S S V R LR +RVLRPL+ + L+ V++ + A+ + I L+ + +FA+IG++ + G F ++C +++K+ T++ G GL + ++Q + + +F+++ AMLT+F +T EGW I+ + D+ Sbjct: 773 AESPSLAEDSKATLNRDHESVRSATSTEVMDHEPMPPESSLFIFSNTNCFRVVCHRIATNSYFVNFILLLIIVSSCMLAAEDPLNSNSKR--NQVLNYFDYFFTAVFTIEITIKIIAYGVILHKGSFCRSAFNLLDFLVVAVSIVSIALR-DSSSQISVV--RILRVLRVLRPLRAINRAKGLKHVVQCVFVAVKTIGNIMLVTVLFNFLFAVIGVQLFKGTF-FSC--TDAEKI-----TKRECQGQYIEFKGPGLTNPVVKDREWQPQTF---------NFNDVPQAMLTLFTVMTFEGWPGILESSMDS 1062 HSP 6 Score: 78.5666 bits (192), Expect = 3.406e-14 Identity = 78/320 (24.38%), Postives = 162/320 (50.62%), Query Frame = 2 Query: 3995 TFQEQGENELIDLDLDKNQKQCIDFAINEKPLCRYMPKDKTTIKY------RVWRLVVSTPFEYF-IMVMIALNTLILMMKYYREEKKASSAATHDREQQAYLNYCNTLIFLNSAFTVMFSIECVLKIMAFGPKNYFRDPWNIFDFITVIGSITDVLVSELQDXXXXXXXXXXXXXXXXXXXXXXQGYTIRILLWTFIQSFKALPYVCLLIAMLFFIYSIIGMQVFGNIKLISEYQINRHNNFQTFTNGLLLLFRCATGESWQEIMLACDNNKPCEKDIENTNNF-DCGSNFTYIYFVSFIFLCSFLMLNLFVAVIMDNF 4930 +F+ + EN+ D+ KN++ D A +++ ++ + K +K R R V T + Y+ ++V + LN+L L +++Y + + + +L+ N L F +F++E V+K+ G YF +N FD + VI S+ ++ ++E D + + LR R R+ K+ R ++ L+ + + S +++ + LL+++ I+S++GMQ+FG + + + R +NF +F L+ +F+ TGE W +M I++ + S +YF+ + + ++++LN+F+A+ +DN Sbjct: 405 SFRRRKEND----DISKNKENQEDSAASDQG---WIDRKKKILKRFHHRLRRSCRKAVKTQWFYWTVIVFVFLNSLTLALEHYNQPEFLTQ----------FLDKANKL------FLALFTLEMVVKMYCLGFHGYFASLFNRFDCLVVISSLLELGLTEAMDQRPIGISMLRCVRLLRIFKVTRYWSSLSNLVASLLNSMRSIMGLLLLLSLFMVIFSLLGMQIFGGKFNLGDEDVPR-SNFDSFWRALVTVFQILTGEDWNAVMYT---------GIQSWGGITESLSAIPILYFIFLVVVGNYILLNVFLAIAVDNL 691 HSP 7 Score: 74.3294 bits (181), Expect = 6.689e-13 Identity = 69/269 (25.65%), Postives = 134/269 (49.81%), Query Frame = 2 Query: 1940 KERCTSFWRTEKHFRFSVRRLVKSQPFYWAVIILVFFNTVCVAIEHYEQGKWLTLFLNYAEYVFLCLFMMEMMIKMYGLSIRVYFQSSFNIFDCVVIAGSLFEIIYGIFVQDSSFGLSVLRALRLLRIFKVTRYWAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXGMQLFGGEFNFEEGKPPQ--NFDTFVKALLTVFQILTGEDWNTVMYNGIQSKGGVKER-----------GTVFS-IYFVLLVVFGNYTLLNVFLAIAVDN 2704 K R T + +F V R+V SQPF + + + NT+ + +++Y + K T L+ F +F++E ++K++ + YF +N+FD VV+ GS+ +I + F R R LR+ K+ + ++ L+ + + S +++ + L+ + I+A++GMQ+FG E + + NF TF ++L+ +F+ TGE+W +M + + GT F+ YF ++ ++N+F+A+ +DN Sbjct: 1130 KARPTRRYIPTNRLQFHVWRVVTSQPFEYLIFAFITGNTILLMMQYYNEPKLYTRVLDGFNIGFTSVFLLECILKLFAFKPKNYFLDRWNLFDFVVVVGSVVDITMNEVSSEQMFAFGFFRLFRALRLVKLLNQGSGIKTLLWTFIKSFQALPYVGLLIIMTFFIYAVVGMQMFGRIAIDPETQINRNNNFQTFPQSLMVLFRSATGENWQLIMLACTDTPNAKCDPNAYPQDTDGLCGTDFAYAYFCSFYAICSFLIINLFVAVIMDN 1398 HSP 8 Score: 65.855 bits (159), Expect = 2.431e-10 Identity = 64/260 (24.62%), Postives = 114/260 (43.85%), Query Frame = 2 Query: 3116 NSLRRFCHFVVNLRYFDLFIMIVICASSIALAAEDPVKEKSLKNNILEFFDYA---FTGVFTVEMILKIIDLGIILHPGSYCRDLWNILDATVVICALVAF----IMGQKPSPTGNKLRGSSAKNLNTIKSLRVLRVLRPLKTINRVPKLKAVFDCVVSSLKNVFNILIVYILFQFIFAVIAVQLFQGKFFYCNDASKSSRETCRGYFFDYAGRSTPETKKRLWQHHDFHFDNILYAMLTLFTVTTGEGWPTVLKNSMES 3874 + LRR C V ++F +++ + +S+ LA E + + L +F D A F +FT+EM++K+ LG Y L+N D VVI +L+ M Q+P I LR +R+LR K L + +++S++++ +L++ LF IF+++ +Q+F GKF + P + +FD+ A++T+F + TGE W V+ ++S Sbjct: 445 HRLRRSCRKAVKTQWFYWTVIVFVFLNSLTLALEHYNQPEFLT----QFLDKANKLFLALFTLEMVVKMYCLGF----HGYFASLFNRFDCLVVISSLLELGLTEAMDQRPI---------------GISMLRCVRLLRIFKVTRYWSSLSNLVASLLNSMRSIMGLLLLLSLFMVIFSLLGMQIFGGKF-------------------NLGDEDVPRS----------NFDSFWRALVTVFQILTGEDWNAVMYTGIQS 652 HSP 9 Score: 64.3142 bits (155), Expect = 7.758e-10 Identity = 72/305 (23.61%), Postives = 130/305 (42.62%), Query Frame = 2 Query: 4145 VVSTPFEYFIMVMIALNTLILMMKYYREEKKASSAATHDREQQAYLNYCNTLIFLNSAFTVMFSIECVLKIMAFG----PKNYFRDPWNIFDFITVIGSITDVLVSELQDXXXXXXXXXXXXXXXXXXXXXXQGYTIRILLWTFIQSFKALPYVCLLIAMLFFIYSIIGMQVF--------------------------------------GNIKLISEYQINRH-NNFQTFTNGLLLLFRCATGESWQEIMLACDNNKPCEKDIENTNNFDCGSNFTYIYFVSFIFLCSFLMLNLFVAVIMDNF 4930 V TPF+ I++ I N L + ++ SS + E ++ F +F++E VLKI+A+G P Y R+ WNI DF+ V+ + ++V +L + LR FR R ++L+ +++++L + I++ L ++ LL+ + IY+IIG+++F G + L N NF L +F+C T E W ++M + ++ G+++ ++YFV+ I SF +LNL + V+ F Sbjct: 71 VFRTPFDVMILITIFANCAALA-AFQPLPEQDSSLINEELEVAEFV------------FLGIFTMESVLKIIAYGFVMHPGAYLRNGWNILDFVIVVVGLATIIV-KLYTPDSFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKALIPLFHIALLVVFVVIIYAIIGVELFMGKLHSTCYDNVTGQPTFDEPHPCSTESEGYSCSNAGPGQVCLKKWEGPNYGITNFDNIGLACLTVFQCITLEGWTDVMYSINDA--------------IGNSWPWLYFVTLIIWGSFFVLNLVLGVLSGEF 347 HSP 10 Score: 53.9138 bits (128), Expect = 9.529e-7 Identity = 43/159 (27.04%), Postives = 77/159 (48.43%), Query Frame = 2 Query: 767 PFEYMVLLTILANCIVLSMERHLPKKDKTLLAGQLELTEKYFLGIFCVEALLKIVALGFCCHKEAYLRNVWNIMDFVVVVTGFLMMFLNIDNHSDSSTVDLRTLRAVRVLRPLKLVAGFPSLQVVLKSIIRAMAPLLQIGLLVLFAITIFAIIGLEFYS 1243 PFEY++ I N I+L M+ + K T + + F +F +E +LK+ F + Y + WN+ DFVVVV + + +N S R R LR +KL+ ++ +L + I++ L +GLL++ I+A++G++ + Sbjct: 1155 PFEYLIFAFITGNTILLMMQYYNEPKLYTRVLDGFNIG---FTSVFLLECILKL----FAFKPKNYFLDRWNLFDFVVVVGSVVDITMN--EVSSEQMFAFGFFRLFRALRLVKLLNQGSGIKTLLWTFIKSFQALPYVGLLIIMTFFIYAVVGMQMFG 1304
BLAST of Voltage dependent L type calcium channel subunit vs. Ensembl Nematostella
Match: EDO35661 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SKR1]) HSP 1 Score: 230.72 bits (587), Expect = 1.406e-60 Identity = 202/699 (28.90%), Postives = 358/699 (51.22%), Query Frame = 2 Query: 3143 VVNLRYFDLFIMIVICASSIALAAEDP-VKEKSLKNNILEFFDYAFTGVFTVEMILKIIDLGIILHPGSYCRDLWNILDATVVICALVAFIMGQKPSPTGNKLRGSSAKNLNTIKSLRVLRVLRPLKTINRVPKLKAVFDCVVSSLKNVFNILIVYILFQFIFAVIAVQLFQGKFFYCNDASKSSRETCRGYFFDYAGRSTPETKKRLWQHHDFHFDNILYAMLTLFTVTTGEGWPTVLKNSMESTNIDNGPIADYRQEMAXXXXXXXXXXXXXXXXXXXALIIITFQE-------QGENELIDLDLDKNQKQCIDFAINEKPLCRYMPKDKTTIKYRVWRLVVSTPFEYFIMVMIALNTLILMMKYYREEKKASSAATHDREQQAYLNYCNTLIFLNSAFTVMFSIECVLKIMAFGPKNYFRDPWNIFDFITVIGSITDVLVSELQDXXXXXXXXXXXXXXXXXXXXX---XQGYTIRILLWTFIQSFKALPYVCLLIAMLFFIYSIIGMQVFGNIKLISEYQINRHNNFQTFTNGLLLLFRCATGESWQEIMLACDNNKP-CEKDIENTNNFDCGSNFTY-IYFVSFIFLCSFLMLNLFVAVIMDNFDYLTRDSSI-LGPHHLDEYIRVWAEYDPGAIGRIHHSEMYEMLRNMEPPVGFGKKCPYRLAYRKLIRMNMPVDENGTVNFTTTLFALIRE 5197 +V + F+ I+ +I ASSI+LA ED + K +L+ + F +FTVEM+LK I LG +Y + WNILD +VI + IM + GN + I+SLR LR RPL+ I+R +K V ++ ++ + N+L+V ++F IF+++ VQ+F GKF C D E C ++ + W++ + +FD + L L V T EGW ++++++++T ID PI + +F++VF I+ FF +N+F+ +II F + G ++ +N + A +KP R + + + + ++ +V S FE FIM+ I +N +++M+++Y S LN FT +F +E +L+I+A K YF +PWN+FDF+ VI SI ++V LQ S ++ LR+ R R+ +LL IR LL++ + S AL + L+ ++ FIY+IIGM +FG++K +N NF+TF + +LLFR T W +I+ ++P C+ + + +CG+ + IY SF+ + +++N+++AVI++N++ + I + ++ + ++W +DP A I ++++ + + ME + K P + A L N+P+ + ++ L AL++ Sbjct: 823 LVEHKVFEGIILFLIAASSISLAFEDVYLDSKPTLKQVLQILNILFAVIFTVEMLLKWIGLGF----KTYFTNPWNILDFVIVIVS----IMVSLATIFGND-------QIAFIRSLRTLRAFRPLRAISRFEGMKVVITSLLHAIPGIGNVLLVCLMFWLIFSIMGVQIFGGKFGKCVDEGG---EKCPASV--VPNKTVCLSNGYRWENSNINFDTVDQGFLALLQVATFEGWMEIMEDAVDATKIDEQPIEENNVSAYLFFVVFIILGTFFTLNLFIGVIIDNFNQLKQQMEAVGSMDVFLTSTQRNWMNALKSAATKKPKKR-IRRPQNKFQGELYDMVQSRKFEVFIMLFITINMVVMMVQHYDHLAVWSKQ------------------ILNLIFTSVFILEAILRIIALR-KGYFLNPWNVFDFVIVISSIIGIIVENLQTSLVINPSLLRVVRVFRVGRLLRFFEAARGIRRLLFSLVISTPALFNIGALLFLIIFIYAIIGMSIFGHVK--KTEALNDVVNFETFGSSFVLLFRLMTSAGWNDILDPLMISEPDCDPNYRGLPSGNCGNKYMAPIYLGSFVVIIFLILINMYIAVILENYNQVMEQEKIGITNEDIELFYQMWELFDPNATQYIPYADLSDFVHQMEGNLRIPK--PNKAACALL---NIPLVKGDKIHCLDLLQALVKR 1474 HSP 2 Score: 160.614 bits (405), Expect = 3.395e-39 Identity = 108/325 (33.23%), Postives = 167/325 (51.38%), Query Frame = 2 Query: 695 SKSLFIFSEENVIRKYA-KIIIEWGPFEY-----MVLLTILANCIVLSMERHLPKKDKTLLAGQLELTEKYFLGIFCVEALLKIVALGFCCHKEAYLRNVWNIMDFVVVVTGFLMMFLNIDNHSDSSTVDLRTLRAVRVLRPLKLVAGFPSLQVVLKSIIRAMAPLLQIGLLVLFAITIFAIIGLEFYSGAFHYTCFKANSDKLPLPIPTEKS-----------LVPCSNSKNGSGLGAYTCPEDYQCKAYWEG-PNYGITSFDNIGYAMLTVFQCITMEGWTDIMYHTNDAIGNRFNW--LYFVPLIILGSFFMLNLVLGVLSG 1609 SKSL++F EN IR+++ K+I P + VLLTIL NC+ L+M E E F I+ +E KI+A GF H+ AYLR+ WN +DF+VV+ G N+ D + +L + RV R L+ ++ L+ ++ +++ +M L + +L LF I IFA+IG++ + G C + L +P T S + C N+ G+ TCP +Y C + G PN+G TSFD+ G+A+LT FQ IT++ W ++ N+ I W +YF +I G FF++NLVL V++ Sbjct: 21 SKSLYLFGPENPIRQFSLKLITNQYPLQLHNRHMFVLLTILVNCVFLAM------------TNPPEQPEYVFAAIYTIEMFCKIIAKGFALHRYAYLRDKWNWLDFIVVILG------NVTISPDVA--NLSGIPTFRVFRALRTISAVKGLKAMVNTLLVSMKMLWDVMVLTLFFICIFALIGMQLFIGELRNKCALPVPENLSVPYRTYASNSSIWYLEDNEPILCGNTT-----GSRTCPTNYTCLPHAGGNPNFGYTSFDHFGWALLTGFQLITLDFWENVY---NNVIYTMGPWYVVYFAVVIFFGPFFLVNLVLAVVAA 317 HSP 3 Score: 127.102 bits (318), Expect = 6.507e-29 Identity = 123/507 (24.26%), Postives = 209/507 (41.22%), Query Frame = 2 Query: 728 VIRKYAKIIIEWGPFEYMVLLTILANCIVLSMERHLPKKDKTLLAGQLELTEKYFLGIFCVEALLKIVALGFCCHKEAYLRNVWNIMDFVVVVTGFLMMFLNIDNHSDSSTVDLRTLRAVRVLRPLKLVAGFPSLQVVLKSIIRAMAPLLQIGLLVLFAITIFAIIGLEFYSGAFHYTCFKANSDKLPLPIPTEKSLVPCSNSKNGSGLGAYTCPEDYQCKAYWEGPNYGITSFDNIGYAMLTVFQCITMEGWTDIMYHTNDAI---------GNRFNWLYFVPLIILGSFFMLNLVLGVLSGXXXXXXXXXXXXXXXLKLRRQQQTEKEFNGYMEWIQKAEEVLLNEATTTSEDKMRIIAARRRAEKQKYKLLGKNQSIPDFEYEDTELYSETKSMKGNIFIRSYAGIRRRRKERCTSFWRTEKHFRFSVRRLVKSQPFYWAVIILVFFNTVCVAIEHYEQ-GKWLTLFLNYAEYVFLCLFMMEMMIKMYGLSIRVYFQSSFNIFD 2218 V+R + ++E FE ++L I A+ I L+ E + K L L++ F IF VE LLK + LGF + Y N WNI+DFV+V+ ++ I + +R+LR +R RPL+ ++ F ++VV+ S++ A+ + + L+ L IF+I+G++ + G F C +K P + K++ + + WE N +FD + L + Q T EGW +IM DA N +L+FV IILG+FF LNL +GV+ F +L++Q + + ++ Q+ L A T K R R + K++ ELY +S K +FI ++ + N V + ++HY+ W LN +F +F++E ++++ L + YF + +N+FD Sbjct: 815 VMRYKVRRLVEHKVFEGIILFLIAASSISLAFE-DVYLDSKPTLKQVLQILNILFAVIFTVEMLLKWIGLGF----KTYFTNPWNILDFVIVIVSIMVSLATI--FGNDQIAFIRSLRTLRAFRPLRAISRFEGMKVVITSLLHAIPGIGNVLLVCLMFWLIFSIMGVQIFGGKFG-KCVDEGGEKCPASVVPNKTVCLSNGYR-------------------WENSN---INFDTVDQGFLALLQVATFEGWMEIMEDAVDATKIDEQPIEENNVSAYLFFVVFIILGTFFTLNLFIGVIIDNFN-------------QLKQQMEAVGSMDVFLTSTQRNWMNALKSAATKKPKK------RIRRPQNKFQ---------------GELYDMVQSRKFEVFI-----------------------------------------MLFITINMVVMMVQHYDHLAVWSKQILN---LIFTSVFILEAILRIIALR-KGYFLNPWNVFD 1212 HSP 4 Score: 110.923 bits (276), Expect = 5.221e-24 Identity = 94/306 (30.72%), Postives = 146/306 (47.71%), Query Frame = 2 Query: 4118 TIKYRVWRLVVSTPFEYFIMVMIALNTLILMMKYYREEKKASSAATHDREQQAYLNYCNTLIFLNSAFTVMFSIECVLKIMAFGPKNYFRDPWNIFDFITVIGSITDVLVSELQDXXXXXXXXXXXXXXXXXXXXXXQGYTIRILLWTFIQSFKALPYVCLLIAMLFFIYSIIGMQVFGN----------------------IKLISEYQINRHN-NFQTFTNGLLLLFRCATGESWQEIML-ACDNNKPCEKDIENTNNFDCGSNFTYIYFVSFIFLCSFLMLNLFVAVIMDNFDYLTRDSSILG 4963 ++Y+V RLV FE I+ +IA +++ L E+ S T + Q LN F V+F++E +LK + G K YF +PWNI DF+ VI SI L + + + LR RA R ++ + + +++++ + + + + V L+ M + I+SI+G+Q+FG + L + Y+ N NF T G L L + AT E W EIM A D K E+ IE N Y++FV FI L +F LNLF+ VI+DNF+ L + +G Sbjct: 815 VMRYKVRRLVEHKVFEGIILFLIAASSISLAF----EDVYLDSKPTLKQVLQ----------ILNILFAVIFTVEMLLKWIGLGFKTYFTNPWNILDFVIVIVSIMVSLATIFGNDQIAFIRSLRTLRAFRPLRAISRFEGMKVVITSLLHAIPGIGNVLLVCLMFWLIFSIMGVQIFGGKFGKCVDEGGEKCPASVVPNKTVCLSNGYRWENSNINFDTVDQGFLALLQVATFEGWMEIMEDAVDATKIDEQPIEENNVS------AYLFFVVFIILGTFFTLNLFIGVIIDNFNQLKQQMEAVG 1100 HSP 5 Score: 90.1225 bits (222), Expect = 1.075e-17 Identity = 67/220 (30.45%), Postives = 124/220 (56.36%), Query Frame = 2 Query: 2030 VIILVFFNTVCVAIEHYEQGKWLTLFLNYAEYVFLCLFMMEMMIKMYGLSIRVYFQSSFNIFDCVVIAGSLFEIIYGIFVQDS-SFGLSVLRALRLLRIFKVTRYWAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXGMQLFGGEFN---FEEGKPPQNFDTFVKALLTVFQILTGEDWNTVMYNGIQSKGGVKERGTVFSIYFVLLVVFGNYTLLN 2677 +I+ + NT+ ++IEH L +N + VF +F++EM++K+ L Y + ++NIFD +V+ S+ + I FV D+ G+SVLR RLLR+ K+ + W+++ +L+ ++ S+ ++ +L +L + + IFA++GMQL G + F P NF F + + +F++L GE W +++ + + G V + FV + GN+ +LN Sbjct: 509 IIVCILLNTLVMSIEHPRLEDPLLTVVNISNEVFTFIFLLEMILKLIALGFLGYIRVAWNIFDGIVVIISIVDFIVNKFVPDAGGTGISVLRTFRLLRVLKLAKSWSTMNSLLATIGKSLGALGNLTVILAIIVYIFAVMGMQLLGNSYTPDKFGGSIPRWNFKDFPHSFMMIFRVLCGE-WIEPLWDCMLATGPVA------MLLFVPAFILGNFIILN 721 HSP 6 Score: 89.7373 bits (221), Expect = 1.419e-17 Identity = 59/197 (29.95%), Postives = 100/197 (50.76%), Query Frame = 2 Query: 3092 AMFIFSPLNSLRRFC------HFVVNLRYFDLFIMIVICASSIALAAEDPVKEKSLKNNILEFFDYAFTGVFTVEMILKIIDLGIILHPGSYCRDLWNILDATVVICALVAFIMGQKPSPTGNKLRGSSAKNLNTIKSLRVLRVLRPLKTINRVPKLKAVFDCVVSSLKNVFNILIVYILFQFIFAVIAVQLFQGKF 3664 ++++F P N +R+F + + L +F+++ I + + LA +P ++ +Y F ++T+EM KII G LH +Y RD WN LD VVI GN NL+ I + RV R LR TI+ V LKA+ + ++ S+K +++++++ + F IFA+I +QLF G+ Sbjct: 23 SLYLFGPENPIRQFSLKLITNQYPLQLHNRHMFVLLTILVNCVFLAMTNPPEQP----------EYVFAAIYTIEMFCKIIAKGFALHRYAYLRDKWNWLDFIVVIL--------------GNVTISPDVANLSGIPTFRVFRALR---TISAVKGLKAMVNTLLVSMKMLWDVMVLTLFFICIFALIGMQLFIGEL 192 HSP 7 Score: 80.8777 bits (198), Expect = 6.158e-15 Identity = 74/282 (26.24%), Postives = 140/282 (49.65%), Query Frame = 2 Query: 1952 TSFWRTEKHFRFSVRRLVKSQPFYWAVIILVFFNTVCVAIE--HYEQGKWLTLFLNYAEYVFLCLFMMEMMIKMYGLSIRVYFQSSFNIFDCVVIAGSLFEIIYGIFVQDSSFGLSVLRALRLLRIFKVTRYWAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXGMQLFGGEFN--FEEG--KPPQ---------------------NFDTFVKALLTVFQILTGEDWNTVMYNGIQS----KGGVKERGTVFSIYFVLLVVFGNYTLLNVFLAIAVDN 2704 + F K R+ VRRLV+ + F ++ L+ +++ +A E + + L L +F +F +EM++K GL + YF + +NI D V++ S+ + IF D + LR LR R + + ++ ++ SLL+++ I ++L + +F LIF+++G+Q+FGG+F +EG K P NFDT + L + Q+ T E W +M + + + + ++E ++FV+ ++ G + LN+F+ + +DN Sbjct: 807 SGFCAVWKVMRYKVRRLVEHKVFEGIILFLIAASSISLAFEDVYLDSKPTLKQVLQILNILFAVIFTVEMLLKWIGLGFKTYFTNPWNILDFVIVIVSIMVSLATIFGNDQIAFIRSLRTLRAFRPLRAISRFEGMKVVITSLLHAIPGIGNVLLVCLMFWLIFSIMGVQIFGGKFGKCVDEGGEKCPASVVPNKTVCLSNGYRWENSNINFDTVDQGFLALLQVATFEGWMEIMEDAVDATKIDEQPIEENNVSAYLFFVVFIILGTFFTLNLFIGVIIDN 1088 HSP 8 Score: 79.337 bits (194), Expect = 1.735e-14 Identity = 70/209 (33.49%), Postives = 112/209 (53.59%), Query Frame = 2 Query: 4163 EYFIMVMIALNTLILMMKYYREEKKASSAATHDREQQAYLNYCNTLIFLNSAFTVMFSIECVLKIMAFGPKNYFRDPWNIFDFITVIGSITDVLVSE-LQDXXXXXXXXXXXXXXXXXXXXXXQGYTIRILLWTFIQSFKALPYVCLLIAMLFFIYSIIGMQVFGNIKLISEY--QINRHNNFQTFTNGLLLLFRCATGESWQEIMLAC 4780 E FI+V I LNTL++ ++ H R + L N N FT +F +E +LK++A G Y R WNIFD I VI SI D +V++ + D+ + LR FR R++KL + T+ LL T +S AL + +++A++ +I++++GMQ+ GN ++ I R NF+ F + +++FR GE W E + C Sbjct: 506 EIFIIVCILLNTLVMSIE-------------HPRLEDPLLTVVN---ISNEVFTFIFLLEMILKLIALGFLGYIRVAWNIFDGIVVIISIVDFIVNKFVPDAGGTGISVLRTFRLLRVLKLAKSWSTMNSLLATIGKSLGALGNLTVILAIIVYIFAVMGMQLLGNSYTPDKFGGSIPRW-NFKDFPHSFMMIFRVLCGE-WIEPLWDC 696 HSP 9 Score: 76.2554 bits (186), Expect = 1.616e-13 Identity = 69/251 (27.49%), Postives = 114/251 (45.42%), Query Frame = 2 Query: 3149 NLRYFDLFIMIVICASSIALAAEDPVKEKSLKNNILEFFDYAFTGVFTVEMILKIIDLGIILHPGSYCRDLWNILDATVVICALVAFIMGQKPSPTGNKLRGSSAKNLNTIKSLRVLRVLRPLKTINRVPKLKAVFDCVVSSLKNVFNILIVYILFQFIFAVIAVQLFQGKFFYCNDASKSSRETCRGYFFDYAGRSTPETKKRLWQHHDFHFDNILYAMLTLFTVTTGEGWPTVLKNSMESTNIDNGPIA 3901 N + ++FI++ I +++ ++ E P E L ++ + FT +F +EMILK+I LG + Y R WNI D VVI ++V FI+ + G G+ L T + LRVL++ + T+N ++ + SL + N+ ++ + +IFAV+ +QL Y D G S P W DF ++ + +F V GE W L + M +T GP+A Sbjct: 501 NGKVMEIFIIVCILLNTLVMSIEHPRLEDPLLT-VVNISNEVFTFIFLLEMILKLIALGFL----GYIRVAWNIFDGIVVIISIVDFIVNKFVPDAG----GTGISVLRTFRLLRVLKLAKSWSTMN------SLLATIGKSLGALGNLTVILAIIVYIFAVMGMQLLGNS-----------------YTPDKFGGSIPR-----WNFKDFP-----HSFMMIFRVLCGE-WIEPLWDCMLAT----GPVA 704 HSP 10 Score: 73.9442 bits (180), Expect = 9.081e-13 Identity = 66/271 (24.35%), Postives = 122/271 (45.02%), Query Frame = 2 Query: 773 EYMVLLTILANCIVLSMERHLPKKDKTLLAGQLELTEKYFLGIFCVEALLKIVALGFCCHKEAYLRNVWNIMDFVVVVTGFLMMFLNIDNHSDSSTVDLRTLRAVRVLRPLKLVAGFPSLQVVLKSIIRAMAPLLQIGLLVLFAITIFAIIGLEFYSGAFHYTCFKANSDKLPLPIPTEKSLVPCSNSKNGSGLGAYTCPEDYQCKAYWEGPNYGITSFDNIGYAMLTVFQCITMEGWTDIMYHTNDAIGNRFNWLYFVPLIILGSFFMLN 1585 E +++ IL N +V+S+E P+ + LL + ++ + F IF +E +LK++ALGF Y+R WNI D +VV+ + +N D+ + LR R+LR LKL + ++ +L +I +++ L + +++ + IFA++G++ ++ DK IP W +F + ++ + +F+ + E W + ++ A G L FVP ILG+F +LN Sbjct: 506 EIFIIVCILLNTLVMSIEH--PRLEDPLLT-VVNISNEVFTFIFLLEMILKLIALGFL----GYIRVAWNIFDGIVVIISIVDFIVN-KFVPDAGGTGISVLRTFRLLRVLKLAKSWSTMNSLLATIGKSLGALGNLTVILAIIVYIFAVMGMQLLGNSY-------TPDKFGGSIPR------------------------------W--------NFKDFPHSFMMIFRVLCGE-WIEPLWDCMLATG-PVAMLLFVPAFILGNFIILN 721
BLAST of Voltage dependent L type calcium channel subunit vs. Ensembl Nematostella
Match: EDO36844 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SHI0]) HSP 1 Score: 223.402 bits (568), Expect = 2.962e-58 Identity = 168/618 (27.18%), Postives = 310/618 (50.16%), Query Frame = 2 Query: 3092 AMFIFSPLNSLRRFCHFVVNLRYFDLFIMIVICASSIALAAEDP-VKEKSLKNNILEFFDYAFTGVFTVEMILKIIDLGIILHPGSYCRDLWNILDATVVICALVAFIMGQKPSPTGNKLRGSSAKNLNTIKSLRVLRVLRPLKTINRVPKLKAVFDCVVSSLKNVFNILIVYILFQFIFAVIAVQLFQGKFFYCNDASKSSRETCRGYFFDYAGRSTPETKKRLWQHHDFHFDNILYAMLTLFTVTTGEGWPTVLKNSMESTNIDNGPIADYRQEMAXXXXXXXXXXXXXXXXXXXALIIITFQEQGENELIDLDLDKNQKQCIDFAI-------NEKPLCRYMPKDKTTIKYRVWRLVVSTPFEYFIMVMIALNTLILMMKYYREEKKASSAATHDREQQAYLNYCNTLIFLNSAFTVMFSIECVLKIMAFGPKNYFRDPWNIFDFITVIGSITDVLVSELQ-----DXXXXXXXXXXXXXXXXXXXXXXQGYTIRILLWTFIQSFKALPYVCLLIAMLFFIYSIIGMQVFGNIKL----ISEYQINRHNNFQTFTNGLLLLFRCATGESWQEIMLACDNNKPCEKDIENTNNFDCG--SNFTYIYFVSFIFLCSF 4888 ++++F+P N R + ++FD +++ I + + +A E P V SL+ +++ Y F G+FT+EM++K+I LG+ + P +Y R WN++D +V+ + V I+ + T N L ++ R LR LRPL+ I+R P LK V + ++SSLK + NI+++ F IF ++ VQLF+GKF YC DA+ T + + G W + +++FDN+ A+LTLF +T +GW ++ + +++ ID PI ++ + I+++ F ++ F +N+ V +++ FQ+ LI+++ ++++ ++ L + P+ + I + F+ I +IALN L + +++Y++ + A+L N + FT +F +E +LKI A G K Y +D WN D + VI SI + + E+ + + + + + + +G IR LL T Q+ + + +L ++FFI+S +G+++FG I I+ ++ H NF++F +L LFR +TG++W I+ + C + E DC + IYF F+ F Sbjct: 910 SLYVFAPDNRFRMLNKELYQNKWFDRTVLLFILLNCVVMALEGPSVLPGSLERRVIDICMYVFLGIFTIEMMVKVIALGLWIGPDAYLRSGWNVMDGFLVVISWVDVIV----TATTN----GQNSILGVLRVFRALRTLRPLRVISRAPGLKIVVETLISSLKPIGNIVLIAATFFIIFGILGVQLFKGKFHYCTDATVPV--TTKTECLENGGS---------WVNREYNFDNLAKALLTLFVFSTKDGWVNIMYDGIDAVGIDKQPIRNHARYNVIYFVGFLLLAGFVVLNMLVGVVVENFQKC--RTLIEMEKKIDEEKKNKKEEKMRREIAEDEALSEHYPRPRKFIH----AVCTHGYFDLGIAAVIALNVLCMALEHYQQPDGLT----------AFLKCANYV------FTAVFILEAILKIFALGIKRYIKDRWNQLDMLIVILSIVGIALEEMTMELPINPTIIRVMRVLRIARVLKLLKTAEG--IRKLLDTVAQALPQVGNLGMLFLLMFFIFSALGIELFGKIDCEKPGITCQGMDEHANFRSFGIAMLTLFRISTGDNWNGILKDTISPDVCRVNPE----IDCSMLEHVAPIYFAVFVLATQF 1480 HSP 2 Score: 157.147 bits (396), Expect = 4.326e-38 Identity = 107/343 (31.20%), Postives = 178/343 (51.90%), Query Frame = 2 Query: 626 TTSMRSLAKRTINLSFPGMQTSTSK--SLFIFSEENVIRKYAKIIIEWGPFEYMVLLTILANCIVLSMERHLPKKDKTLLAGQLE-----LTEKYFLGIFCVEALLKIVALGFCCHKEAYLRNVWNIMD-FVVVVTGFLMMFLNIDNHSDSSTVDLRTLRAVRVLRPLKLVAGFPSLQVVLKSIIRAMAPLLQIGLLVLFAITIFAIIGLEFYSGAFHYTCFKANSDKLPLPIPTEKSLVPCSNSKNGSGLGAYTCPEDYQCKAYWEGPNYGITSFDNIGYAMLTVFQCITMEGWTDIMYHTNDAIG---------NRFNWLYFVPLIILGSFFMLNLVLGVL 1603 T M T+++ P S SL++F+ +N R K + + F+ VLL IL NC+V+++E ++L G LE + FLGIF +E ++K++ALG +AYLR+ WN+MD F+VV++ ++ N +S LR RA+R LRPL++++ P L++V++++I ++ P+ I L+ IF I+G++ + G FHY C A +P+ T+ + +NG W Y +FDN+ A+LT+F T +GW +IMY DA+G R+N +YFV ++L F +LN+++GV+ Sbjct: 883 TPCMSPTDNPTVDIKVPTSCCSKRADWSLYVFAPDNRFRMLNKELYQNKWFDRTVLLFILLNCVVMALE------GPSVLPGSLERRVIDICMYVFLGIFTIEMMVKVIALGLWIGPDAYLRSGWNVMDGFLVVISWVDVIVTATTNGQNSILGVLRVFRALRTLRPLRVISRAPGLKIVVETLISSLKPIGNIVLIAATFFIIFGILGVQLFKGKFHY-CTDAT-----VPVTTKTECL-----ENGGS---------------WVNREY---NFDNLAKALLTLFVFSTKDGWVNIMYDGIDAVGIDKQPIRNHARYNVIYFVGFLLLAGFVVLNMLVGVV 1190 HSP 3 Score: 140.198 bits (352), Expect = 6.393e-33 Identity = 106/300 (35.33%), Postives = 168/300 (56.00%), Query Frame = 2 Query: 1829 NQSIPDFEYEDTELYSETKSMKGNIFIRSYAGIRRRRKERCTSFWRTEKHFRFSVRRLVKSQPFYWAVIILVFFNTVCVAIEHYEQGKWLTLFLNYAEYVFLCLFMMEMMIKMYGLSIRVYFQSSFNIFDCVVIAGSLFEIIYGIFVQDSSFGLSVLRALRLLRIFKVTRYWAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXGMQLFGGEFNF--EEG---KPPQNFDTFVKALLTVFQILTGEDWNTVMYNGIQSKGGVKERGTVFSIYFVLLVVFGNYTLLNVFLAIAVDNLAN 2713 N S DF + + GN S + +S R K FR V S+ F + ++ +F NT+ + IE+Y Q + +T L Y+F +F +EM++K+ GL Y + +FNIFD ++ S+ E +F D S G+SVLR+ RLLR+FK+ R+ +LR +L ++++M ++++ L LL +F+ ++LGM LFGG++ F +EG NFD A++TVFQ+LT EDWN VMY+G+++ K G +YF+LL+ GNY L N+ +AI V+ A+ Sbjct: 351 NASNADFNSGASTSEPPVSGVSGNSLAESETDLSDDEDTSESSPRRCAK-FRDGCASSVDSKWFMYVIMGAIFVNTLTMGIEYYGQPQKMTDVLEIFNYIFTAIFGIEMIMKLIGLGFYGYIKDAFNIFDGTIVIISVVE----LFGDDDS-GISVLRSFRLLRVFKLVRFLPALRRQLLVMIHTMDNVMTFLALLVIFMFTASILGMNLFGGKYRFPNDEGVMETSRANFDDLFWAIVTVFQVLTQEDWNIVMYDGMRATS--KWAG----LYFILLMTIGNYILFNLLVAILVEGFAS 638 HSP 4 Score: 97.4413 bits (241), Expect = 6.762e-20 Identity = 67/252 (26.59%), Postives = 123/252 (48.81%), Query Frame = 2 Query: 3125 RRFCHFVVNLRYFDLFIMIVICASSIALAAEDPVKEKSLKNNILEFFDYAFTGVFTVEMILKIIDLGIILHPGSYCRDLWNILDATVVICALVAFIMGQKPSPTGNKLRGSSAKNLNTIKSLRVLRVLRPLKTINRVPKLKAVFDCVVSSLKNVFNILIVYILFQFIFAVIAVQLFQGKFFYCNDASKSSRETCRGYFFDYAGRSTPETKKRLWQHHDFHFDNILYAMLTLFTVTTGEGWPTVLKNSMESTN 3880 R C V+ ++F IM I +++ + E + + + ++LE F+Y FT +F +EMI+K+I LG Y +D +NI D T+VI ++V +L G ++ ++S R+LRV K + +P L+ ++ ++ NV L + ++F F +++ + LF GK+ + ND + ET R +FD++ +A++T+F V T E W V+ + M +T+ Sbjct: 401 RDGCASSVDSKWFMYVIMGAIFVNTLTMGIEYYGQPQKM-TDVLEIFNYIFTAIFGIEMIMKLIGLGFY----GYIKDAFNIFDGTIVIISVV-------------ELFGDDDSGISVLRSFRLLRVF---KLVRFLPALRRQLLVMIHTMDNVMTFLALLVIFMFTASILGMNLFGGKYRFPND--EGVMETSRA-----------------------NFDDLFWAIVTVFQVLTQEDWNIVMYDGMRATS 606 HSP 5 Score: 91.6633 bits (226), Expect = 3.501e-18 Identity = 63/221 (28.51%), Postives = 101/221 (45.70%), Query Frame = 2 Query: 1067 LRTLRAVRVLRPLKLVAGFPSLQVVLKSIIRAMAPLLQIGLLVLFAITIFAIIGLEFYSGAFHYTCFK-------------------ANSDKLPLPIPTEK-------SLVPCSNSKN---GSGLGAYTCPEDYQ------------CKAYWEGPNYGITSFDNIGYAMLTVFQCITMEGWTDIMYHTNDAIGNRFNWLYFVPLIILGSFFMLNLVLGVLS 1606 + +RA+RVLRPL+ + PS+++++ ++ + L + + +IF I+G++ + G C S L +P + +P S + G Y+ +Y C P Y SFDNI A + +FQ IT+EGWTDIMY+ DA G +N++YFV LI++GS+FM NL L V++ Sbjct: 1 MTAVRAIRVLRPLRAINRVPSIRILVTLLLDTLPMLGNVLAMCSLIFSIFGIVGVQMWQGVLRSRCVAQLPGNLSANQLNISAFYQPGGSSDLVCSLPENSGDKHCTSAFIPASTAHGRECGLTYEQYSNRSNYTNVCANWNQYYTLCADMGINPLYDAVSFDNILIAWVAIFQVITLEGWTDIMYYIQDAHG-FWNFIYFVVLIVIGSYFMTNLCLVVIT 220 HSP 6 Score: 85.1149 bits (209), Expect = 4.030e-16 Identity = 68/280 (24.29%), Postives = 134/280 (47.86%), Query Frame = 2 Query: 770 FEYMVLLTILANCIVLSMERH-LPKKDKTLLAGQLELTEKYFLGIFCVEALLKIVALGFCCHKEAYLRNVWNIMDFVVVVTGFLMMFLNIDNHSDSSTVDLRTLRAVRVLRPLKLVAGFPSLQVVLKSIIRAMAPLLQ-IGLLVLFAITIFAIIGLEFYSGAFHYTCFKANSDKLPLPIPTEKSLVPCSNSKNGSGLGAYTCPEDYQCKAYWEGPNYGITSFDNIGYAMLTVFQCITMEGWTDIMYHTNDAIGNRFNWLYFVPLIILGSFFMLNLVLGVL 1603 F Y+++ I N + + +E + P+K + LE+ F IF +E ++K++ LGF Y+++ +NI D +V+ + +F + D+ + LR+ R+LR KLV P+L+ L +I M ++ + LLV+F T +I+G+ + G + + P ++ ++ S + +FD++ +A++TVFQ +T E W +MY A +++ LYF+ L+ +G++ + NL++ +L Sbjct: 413 FMYVIMGAIFVNTLTMGIEYYGQPQK----MTDVLEIFNYIFTAIFGIEMIMKLIGLGF----YGYIKDAFNIFDGTIVIISVVELFGDDDS-------GISVLRSFRLLRVFKLVRFLPALRRQLLVMIHTMDNVMTFLALLVIFMFTA-SILGMNLFGGKYRF--------------PNDEGVMETSRA-----------------------------NFDDLFWAIVTVFQVLTQEDWNIVMYDGMRAT-SKWAGLYFILLMTIGNYILFNLLVAIL 632 HSP 7 Score: 82.4185 bits (202), Expect = 2.339e-15 Identity = 65/228 (28.51%), Postives = 110/228 (48.25%), Query Frame = 2 Query: 4319 FTVMFSIECVLKIMAFG----PKNYFRDPWNIFDFITVIGSITDVLVSEL---QDXXXXXXXXXXXXXXXXXXXXXXQGYTIRILLWTFIQSFKALPYVCLLIAMLFFIYSIIGMQVF---------GNIKLISEYQ--------INRHNNFQTFTNGLLLLFRCATGESWQEIMLACDNNKPCEKDIENTNNFDCGSNFTYIYFVSFIFLCSFLMLNLFVAVIMDNF 4930 F +F+IE ++K++A G P Y R WN+ D V+ S DV+V+ Q+S L R R R ++++ + ++I++ T I S K + + L+ A F I+ I+G+Q+F + + ++ + +NR NF LL LF +T + W IM D D + N + + IYFV F+ L F++LN+ V V+++NF Sbjct: 972 FLGIFTIEMMVKVIALGLWIGPDAYLRSGWNVMDGFLVVISWVDVIVTATTNGQNSILGVLRVFRALRTLRPLRVISRAPGLKIVVETLISSLKPIGNIVLIAATFFIIFGILGVQLFKGKFHYCTDATVPVTTKTECLENGGSWVNREYNFDNLAKALLTLFVFSTKDGWVNIMY--DGIDAVGIDKQPIRNH---ARYNVIYFVGFLLLAGFVVLNMLVGVVVENF 1194 HSP 8 Score: 80.8777 bits (198), Expect = 7.723e-15 Identity = 79/277 (28.52%), Postives = 138/277 (49.82%), Query Frame = 2 Query: 1970 EKHFRFSVRRLVKSQPFYWAVIILVFFNTVCVAIEHYE--QGKWLTLFLNYAEYVFLCLFMMEMMIKMYGLSIRV----YFQSSFNIFDCVVIAGSLFEIIYGIFV--QDSSFG-LSVLRALRLLRIFKVTRYWAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXGMQLFGGEFNF---------------EEGKP----PQNFDTFVKALLTVFQILTGEDWNTVMYNGIQSKG----GVKERGTVFSIYFVLLVVFGNYTLLNVFLAIAVDN 2704 + FR + L +++ F V++ + N V +A+E G ++ YVFL +F +EMM+K+ L + + Y +S +N+ D ++ S ++I Q+S G L V RALR LR +V L+ +V +L++S++ I +++ + F +IF +LG+QLF G+F++ E G NFD KALLT+F T + W +MY+GI + G ++ IYFV ++ + +LN+ + + V+N Sbjct: 917 DNRFRMLNKELYQNKWFDRTVLLFILLNCVVMALEGPSVLPGSLERRVIDICMYVFLGIFTIEMMVKVIALGLWIGPDAYLRSGWNVMDGFLVVISWVDVIVTATTNGQNSILGVLRVFRALRTLRPLRVISRAPGLKIVVETLISSLKPIGNIVLIAATFFIIFGILGVQLFKGKFHYCTDATVPVTTKTECLENGGSWVNREYNFDNLAKALLTLFVFSTKDGWVNIMYDGIDAVGIDKQPIRNHARYNVIYFVGFLLLAGFVVLNMLVGVVVEN 1193 HSP 9 Score: 79.337 bits (194), Expect = 1.949e-14 Identity = 62/204 (30.39%), Postives = 112/204 (54.90%), Query Frame = 2 Query: 2018 FYWAVIILVFFNTVCVAIEHYEQGKWLTLFLNYAEYVFLCLFMMEMMIKMYGLSIRVYFQSSFNIFDCVVIAGSLFEIIYGIFVQDSSFGLS-------VLRALRLLRIFKVTRYWAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXGMQLFGGEFNFEEGKPPQ------NFDTFVKALLTVFQILTGEDWNTVMYNGIQ 2590 F + ++ N +C+A+EHY+Q LT FL A YVF +F++E ++K++ L I+ Y + +N D +++ S I GI +++ + L V+R LR+ R+ K+ + +R L+ ++ ++ + +L L L IF+ LG++LFG + G Q NF +F A+LT+F+I TG++WN ++ + I Sbjct: 1249 FDLGIAAVIALNVLCMALEHYQQPDGLTAFLKCANYVFTAVFILEAILKIFALGIKRYIKDRWNQLDMLIVILS----IVGIALEEMTMELPINPTIIRVMRVLRIARVLKLLKTAEGIRKLLDTVAQALPQVGNLGMLFLLMFFIFSALGIELFGKIDCEKPGITCQGMDEHANFRSFGIAMLTLFRISTGDNWNGILKDTIS 1448 HSP 10 Score: 65.855 bits (159), Expect = 2.306e-10 Identity = 59/259 (22.78%), Postives = 112/259 (43.24%), Query Frame = 2 Query: 734 RKYAKIIIEWGPFEYMVLLTILANCIVLSMERHLPKKDKTLLAGQLELTEKYFLGIFCVEALLKIVALGFCCHKEAYLRNVWNIMDFVVVVTGFLMMFLN-IDNHSDSSTVDLRTLRAVRVLRPLKLVAGFPSLQVVLKSIIRAMAPLLQIGLLVLFAITIFAIIGLEFYSGAFHYTCFKANSDKLPLPIPTEKSLVPCSNSKNGSGLGAYTCPEDYQCKAYWEGPNYGITSFDNIGYAMLTVFQCITMEGWTDIMYHT 1507 RK+ + G F+ + I N + +++E H + D L L+ F +F +EA+LKI ALG + Y+++ WN +D ++V+ + + L + + +R +R +R+ R LKL+ ++ +L ++ +A+ + +G+L L IF+ +G+E + I EK + C G+ + +F + G AMLT+F+ T + W I+ T Sbjct: 1237 RKFIHAVCTHGYFDLGIAAVIALNVLCMALE-HYQQPDG--LTAFLKCANYVFTAVFILEAILKIFALGI----KRYIKDRWNQLDMLIVILSIVGIALEEMTMELPINPTIIRVMRVLRIARVLKLLKTAEGIRKLLDTVAQALPQVGNLGMLFLLMFFIFSALGIELFGK-----------------IDCEKPGITC------QGMDEH-------------------ANFRSFGIAMLTLFRISTGDNWNGILKDT 1446 HSP 11 Score: 61.2326 bits (147), Expect = 5.825e-9 Identity = 60/263 (22.81%), Postives = 107/263 (40.68%), Query Frame = 2 Query: 4160 FEYFIMVMIALNTLILMMKYYREEKKASSAATHDREQQAYLNYCNTLIFLNSAFTVMFSIECVLKIMAFGPKNYFRDPWNIFDFITVIGSITDVLVSELQDXXXXXXXXXXXXXXXXXXXXXXQGYTIRILLWTFIQSFKALPYVCLLIAMLFFIYSIIGMQVFG------NIKLISEYQINRHNNFQTFTNGLLLLFRCATGESWQEIMLACDNNKPCEKDIENTNNFDCGSNFTYIYFVSFIFLCSFLMLNLFVAVIMDNF 4930 F Y IM I +NTL + ++YY + +K + + L N FT +F IE ++K++ G Y +D +NIFD VI S+ ++ + S L L +R L I + + L+ + F SI+GM +FG N + + E NF ++ +F+ T E W +M + S + +YF+ + + ++++ NL VA++++ F Sbjct: 413 FMYVIMGAIFVNTLTMGIEYYGQPQKMT----------------DVLEIFNYIFTAIFGIEMIMKLIGLGFYGYIKDAFNIFDGTIVIISVVELFGDDDSGISVLRSFRLLRVFKLVRFLP-----ALRRQLLVMIHTMDNVMTFLALLVIFMFTASILGMNLFGGKYRFPNDEGVME---TSRANFDDLFWAIVTVFQVLTQEDWNIVMY---------------DGMRATSKWAGLYFILLMTIGNYILFNLLVAILVEGF 636 HSP 12 Score: 51.6026 bits (122), Expect = 4.860e-6 Identity = 44/185 (23.78%), Postives = 70/185 (37.84%), Query Frame = 2 Query: 3479 IKSLRVLRVLRPLKTINRVPKLKAVFDCVVSSLKNVFNILIVYILFQFIFAVIAVQLFQG---------------------KFFY---------CNDASKSSRETCRGYFF---------------DYAGRSTPETKKRLWQHH--------------DFHFDNILYAMLTLFTVTTGEGWPTVL 3856 + ++R +RVLRPL+ INRVP ++ + ++ +L + N+L + L IF ++ VQ++QG FY C+ S + C F Y+ RS W + FDNIL A + +F V T EGW ++ Sbjct: 1 MTAVRAIRVLRPLRAINRVPSIRILVTLLLDTLPMLGNVLAMCSLIFSIFGIVGVQMWQGVLRSRCVAQLPGNLSANQLNISAFYQPGGSSDLVCSLPENSGDKHCTSAFIPASTAHGRECGLTYEQYSNRSNYTNVCANWNQYYTLCADMGINPLYDAVSFDNILIAWVAIFQVITLEGWTDIM 185
BLAST of Voltage dependent L type calcium channel subunit vs. Ensembl Nematostella
Match: EDO46797 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RP56]) HSP 1 Score: 214.542 bits (545), Expect = 1.263e-55 Identity = 209/707 (29.56%), Postives = 355/707 (50.21%), Query Frame = 2 Query: 3146 VNLRYFDLFIMIVICASSIALAAED-PVKEKSLKNNILEFFDYAFTGVFTVEMILKIIDLGIILHPGSYCRDLWNILDATVV-ICALVAFIMGQKPSPTGNKLRGSSAKNLNTIKSLRVLRVLRPLKTINRVPKLKAVFDCVVSSLKNVFNILIVYILFQFIFAVIAVQLFQGKFFYCNDA--SKSSRETCRGYFFDYAGRSTPETKKRLWQHHDFHFDNILYAMLTLFTVTTGEGWPTVLKNSMESTNIDNGPIADYRQEMAXXXXXXXXXXXXXXXXXXXALIIITF----QEQGENELIDLDLDKNQKQCIDF----AINEKPLCRYMPKDKTTIKYRVWRLVVSTPFEYFIMVMIALNTLILMMKYYREEKKASSAATHDREQQAYLNYCNTLIFLNSAFTVMFSIECVLKIMAFGPKNYFRDPWNIFDFITVIGSITDV---LVSELQDXXXXXXXXXXXXXXXXXXXXXXQGYTIRILLWTFIQSFKALPYVCLLIAMLFFIYSIIGMQVFGNIKLISEYQINRHNNFQTFTNGLLLLFRCATGESWQEIMLACDNNKP-CEKDIENTNNFDCGSNFTYI-YFVSFIFLCSFLMLNLFVAVIMDNFDYLTRDSSI-LGPHHLDEYIRVWAEYDPGAIGRIHHSEMYEMLRNMEPPVGFGKKCPYRLAY--RKLIR-MNMPVDENGTVNFTTTLFALIRESL 5203 V RYF+ FI+ + SS L ED + +K L F ++ F +F++E ILK+I G + SY +WN LDA +V +C VA + + P NL+ +S R +R LRPL+ I+R+ +K V + + +++ + ++L+V +LF +F++ VQLF GKF+ C +A K S A P+ + W + + +FDN++ L L V T EGW V+ ++++ST ID P + +++VF IV FF +N+FV +II F ++ E + + L ++Q++ + A + P R P D + +++ LV S FE FI+ +I N ++M+++Y + + NY IFL +E ++KI+A +YF+ W+IFDF+ V+ SI + + +E S L LR+FR ARL+++++ IR LL I S AL + L+ ++ FIY+IIGM FGNIK + +N NF+TF++ ++L+FR TG W +I+ A P C+ + N +CG + Y V++I +++N+++AV++DN + + L Y +A + G + + LR + + K P+++A+ +LIR M +PV E V+ L L+++ L Sbjct: 790 VEHRYFEWFILFTVMVSSFTLVFEDIHLHQKPDLERALNFLNFLFAAIFSLEFILKVIGFGFV----SYFTSVWNCLDALIVSVCVSVACLF-ENP-------------NLSVFRSFRTVRGLRPLRAISRLGGMKVVINALFAAIPGIGSVLVVSMLFWLMFSISGVQLFAGKFYKCVNAEDEKLSPSVIPN---KTACLDHPDYR---WVNANVNFDNVINGFLALLQVATYEGWMEVMADAVDSTKIDQQPSYEANLIAYAYFVVFIIVGSFFVLNLFVGVIIDNFNTLKKKYEEINSMGMLLTESQRKWVQILMAAAKRKPPSNRLRPTD--CFRGKLFDLVSSNQFEVFILTVIMCNMGMMMVQHYDQPPLTTVIG----------NYVLVGIFL---------LEAIIKIIAMR-LHYFKKAWSIFDFVVVVSSIVGMYLGMSTESAVVSPGLLRVLRVFRVARLLRVVQFAKRIRQLLVAIIISMPALFNIGTLLFLVMFIYAIIGMSSFGNIK--KQGALNDLVNFETFSSSIILIFRLGTGTGWNDILDALVVQPPHCDPNFGGLPNGNCGFPIGAVFYLVTYIVSVFLIIVNMYIAVLLDNVNRAHENDEFGLSKDKFKSYYHTFANFSMG--------KQFLPLRVLPEFLAALDK-PFKIAHPSEELIRKMKIPVREGDLVHCFDLLKVLVKKIL 1439 HSP 2 Score: 192.971 bits (489), Expect = 4.083e-49 Identity = 180/744 (24.19%), Postives = 350/744 (47.04%), Query Frame = 2 Query: 608 IDDGSKTTSMRSLAKRTINLSFPGMQTSTSKSLFIFSEENVIRKYAKIIIEWGPFEYMVLLTILANCIVLSMERHLPKKDKTLLAGQLELTEKYFLGIFCVEALLKIVALGFCCHKEAYLRNVWNIMDFVVVVTGFLMMFLNIDNHSDSSTVDLRTLRAVRVLRPLKLVAGFPSLQVVLKSIIRAMAPLLQIGLLVLFAITIFAIIGLEFYSGAFHYTCFKANSDKLPLPIPT-----EKSLVPCSNSKNGSGLGAYTCPEDYQCKAY-WEGPNYGITSFDNIGYAMLTVFQCITMEGWTDIMYHTNDAIGNRFNWLYFVPLIILGSFFMLNLVLGVLSGXXXXXXXXXXXXXXXLKLRRQQQTEKEFNG---YMEWI------------QKAEEVLLNEA------------TTTSEDKMRIIAARRRAEKQKYKLLGKNQS---IPDFEYEDTELYSETKSMKGNIFIRSYAGIRRRRKERCTSFWRTEKHFRFSVRRLVK--SQPFYWAVII-LVFFNTVCVAIEHYEQGKWLTLFLNYAEYVFLCLFMMEMMIKMYGLSIRVYFQSSFNIFDCVVIAGSLFEIIYGIFVQDSSFGLSVLRALRLLRIFKVTRYWAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXGMQLFGGEFNFE----EGKPPQNFDTFVKALLTVFQILTGEDWNTVMYNGIQSKGGVKERGTVFSIYFVLLVVFGNYTLLNVFLAIAVDNLA 2710 I T + L+KR + + + S + SL + +R + ++I FE +V L IL NCI+L + P ++ E F I+ +E + KI++ GF AYLR+ WN +D +VV +L + +I L +R +RVLR + ++ L+ ++ S++R++ L + +L LF++ + A+IGL+ ++G C ++ + P+ E + C S A CP +Y C A+ P++G T+FD+IG++++ FQ +TM+ W ++ ++G + +YFV I SF++LNLVL V+ + E + ++ T+ + W+ + + L+ ++ T + + R+ +R + ++L +S PD E E+T+ + S+ G + G + + C + R + + LV+ +P + +I L+ NTV + + ++ LT L+ +F LF++EM++K++ + Y + +N+FD V+I S G +S G+S+ R LRLLR+ + + W ++ L+ ++ +S+ I ++ +L + I +FA++GM++FG + E G P NF F + + VF+IL E W +++ + + T ++F+ ++ GN+ +LN+F+A+ +++ A Sbjct: 9 ISQHPSTATFLILSKRFNSSGYQAYRFSRTASLLCLGPVHPLRMFCILLITHPYFEIIVTLVILVNCIILGLND--PPEE----------AEYIFTAIYTLEMICKIISRGFVKDSYAYLRDTWNWLDSLVVFLSYLSLAPDI--------ASLSGIRTLRVLRAFRTISALKGLRAMVNSLLRSLKLLTDVLVLFLFSLCVLALIGLQLFTGELRNKCVLETANATTINNPSSWYHREGEPLLCGFSST-----AGRCPANYTCVAHVGPNPDHGFTNFDDIGWSLVMAFQILTMDFWENLYDRVLRSMGEWY-MMYFVVGIFSCSFYLLNLVLAVVYMSYHHEMNLTDNEVTQSQVTHSPVTQSQVTHSPVTQSWVTHSPVTQSRVSQSRVTQSLVTQSWLMQSLVTQSPVTESRVSQSRVTQSRAHPKTDTIQVLEPLESHLYPPDEEEEETKPLTP-PSLNGIVL-----GEDQEKGVLCPKYPRLSR----ACSALVEFIQRPLFDGIIAGLILLNTVVLTMYYHGMPDDLTFVLDILNAIFTGLFILEMIVKIFAFGLVKYICNKWNLFDSVIIITSAVAYFLG-----TSTGVSIFRILRLLRVLYLAQSWETMAKLIRAIAHSVDPIFNITCILGVIIYVFAVVGMRVFGPHYTAEAFGSRGIPRWNFTDFTHSFMMVFRILCSE-WVEPLWDCM------RVTNTAALLFFLPALIVGNFIVLNLFVALLLNSFA 704 HSP 3 Score: 109.768 bits (273), Expect = 1.077e-23 Identity = 150/686 (21.87%), Postives = 285/686 (41.55%), Query Frame = 2 Query: 770 FEYMVLLTILANCIVLSMERHLPKKDKTLLAGQLELTEKYFLGIFCVEALLKIVALGFCCHKEAYLRNVWNIMDFVVVVTGFLMMFLNIDNHSDSSTVDLRTLRAVRVLRPLKLVAGFPSLQVVLKSIIRAMAPLLQIGLLVLFAITIFAIIGLEFYSGAFHYTCFKANSDKLPLPIPTEKSLVPCSNSKNGSGLGAYTCPEDYQCKAYWEGPNYGITSFDNIGYAMLTVFQCITMEGWTDIMYHTNDAIGNRFNWLYFVPLIILGSFFMLNLVLGVLSGXXXXXXXXXXXXXXXLKLRRQQQTEKEFNGYMEWIQKAEEVLLNEATTTSEDKMRIIAARRRAEKQKY-KLLGKNQSIPDFEYEDTELYSETKSMKGNIFIRSYAGIRRRRKERCTSFWRTEKHFRFSVRRLVKSQPFYWAVIILVFFNTVCVAIE--HYEQGKWLTLFLNYAEYVFLCLFMMEMMIKMYGLSIRVYFQSSFNIFDCVVIA-----GSLFEIIYGIFVQDSSFGLSVLRALRLLRIFKVTRYWAXXXXXXXXXXXXXXX---XXXXXXXXXXXXXXXXXXGMQLFGGEF----NFEEGK-PPQ---------------------NFDTFVKALLTVFQILTGEDWNTVMYNGIQS----KGGVKERGTVFSIYFVLLVVFGNYTLLNVFLAIAVDN 2704 F+ ++ IL N +VL+M H D T + L++ F G+F +E ++KI A G Y+ N WN+ D V+++T + FL ++ + R +R+LR L L + ++ ++++I ++ P+ I ++ I +FA++G+ + HYT S +P W +F + ++ + VF+ + E W + ++ + N L+F+P +I+G+F +LNL + +L FA ++++ +E +E+ +N + + R R + Y + + N++ + E + + E + G ++ C W FR VR V+ + F W ++ V ++ + E H Q L LN+ ++F +F +E ++K+ G YF S +N D ++++ LFE + LSV R+ R +R + R + L + + + + I S+L + LF L+F++ G+QLF G+F N E+ K P NFD + L + Q+ T E W VM + + S + E + YFV+ ++ G++ +LN+F+ + +DN Sbjct: 482 FDGIIAGLILLNTVVLTMYYHGMPDDLTFV---LDILNAIFTGLFILEMIVKIFAFGLV----KYICNKWNLFDSVIIITSAVAYFLG-------TSTGVSIFRILRLLRVLYLAQSWETMAKLIRAIAHSVDPIFNITCILGVIIYVFAVVGMRVFGP--HYTAEAFGSRGIP----------------------------------RW--------NFTDFTHSFMMVFRILCSE-WVEPLWDCMR-VTNTAALLFFLPALIVGNFIVLNLFVALLLNSFA---------------KKEEDLHRE---------ASEQPYVNPCSCLAH------LTRTRKTRMYYTQAVNNNKNTKRYIVEIDDCFPEC--------CMNACGCTSGQQHFC---WL---KFRCRVRCFVEHRYFEWFILFTVMVSSFTLVFEDIHLHQKPDLERALNFLNFLFAAIFSLEFILKVIGFGFVSYFTSVWNCLDALIVSVCVSVACLFE----------NPNLSVFRSFRTVRGLRPLRAISRLGGMKVVINALFAAIPGIGSVLVVSMLFWLMFSISGVQLFAGKFYKCVNAEDEKLSPSVIPNKTACLDHPDYRWVNANVNFDNVINGFLALLQVATYEGWMEVMADAVDSTKIDQQPSYEANLIAYAYFVVFIIVGSFFVLNLFVGVIIDN 1053 HSP 4 Score: 101.293 bits (251), Expect = 4.626e-21 Identity = 85/301 (28.24%), Postives = 142/301 (47.18%), Query Frame = 2 Query: 734 RKYAKIIIEWGPFEYMVLLTILANCIVLSMER-HLPKKDKTLLAGQLELTEKYFLGIFCVEALLKIVALGFCCHKEAYLRNVWNIMDFVVVVTGFLMMFLNIDNHSDSSTVDLRTLRAVRVLRPLKLVAGFPSLQVVLKSIIRAMAPLLQIGLLVLFAITIFAIIGLEFYSGAFHYTCFKANSDKL-PLPIPTEKSLVPCSNSKNGSGLGAYTCPEDYQCKAYWEGPNYGITSFDNIGYAMLTVFQCITMEGWTDIMYHTNDAI---------GNRFNWLYFVPLIILGSFFMLNLVLGVL 1603 R + +E FE+ +L T++ + L E HL +K L L F IF +E +LK++ GF +Y +VWN +D ++V + L +N + S R+ R VR LRPL+ ++ ++VV+ ++ A+ + + ++ + +F+I G++ ++G F Y C A +KL P IP + + C + DY+ W N +FDN+ L + Q T EGW ++M D+ N + YFV II+GSFF+LNL +GV+ Sbjct: 783 RCRVRCFVEHRYFEWFILFTVMVSSFTLVFEDIHLHQKPD--LERALNFLNFLFAAIFSLEFILKVIGFGFV----SYFTSVWNCLDALIVSVCVSVACL-FENPNLSV---FRSFRTVRGLRPLRAISRLGGMKVVINALFAAIPGIGSVLVVSMLFWLMFSISGVQLFAGKF-YKCVNAEDEKLSPSVIPNKTA---CLDHP------------DYR----WVNAN---VNFDNVINGFLALLQVATYEGWMEVMADAVDSTKIDQQPSYEANLIAYAYFVVFIIVGSFFVLNLFVGVI 1050 HSP 5 Score: 97.8265 bits (242), Expect = 5.112e-20 Identity = 56/192 (29.17%), Postives = 102/192 (53.12%), Query Frame = 2 Query: 3089 SAMFIFSPLNSLRRFCHFVVNLRYFDLFIMIVICASSIALAAEDPVKEKSLKNNILEFFDYAFTGVFTVEMILKIIDLGIILHPGSYCRDLWNILDATVVICALVAFIMGQKPSPTGNKLRGSSAKNLNTIKSLRVLRVLRPLKTINRVPKLKAVFDCVVSSLKNVFNILIVYILFQFIFAVIAVQLFQGKF 3664 +++ P++ LR FC ++ YF++ + +VI + I L DP +E +Y FT ++T+EMI KII G + +Y RD WN LD+ VV + + S A ++ ++ +R LRVLR +TI+ + L+A+ + ++ SLK + ++L++++ + A+I +QLF G+ Sbjct: 39 ASLLCLGPVHPLRMFCILLITHPYFEIIVTLVILVNCIILGLNDPPEEA----------EYIFTAIYTLEMICKIISRGFVKDSYAYLRDTWNWLDSLVVFLSYL-----------------SLAPDIASLSGIRTLRVLRAFRTISALKGLRAMVNSLLRSLKLLTDVLVLFLFSLCVLALIGLQLFTGEL 203 HSP 6 Score: 73.9442 bits (180), Expect = 8.695e-13 Identity = 53/158 (33.54%), Postives = 87/158 (55.06%), Query Frame = 2 Query: 770 FEYMVLLTILANCIVLSMERHLPKKDKTLLAGQLELTEKYFLGIFCVEALLKIVALGFCCHKEAYLRNVWNIMDFVVVVTGFLMMFLNIDNHSDSSTVD---LRTLRAVRVLRPLKLVAGFPSLQVVLKSIIRAMAPLLQIGLLVLFAITIFAIIGLE 1234 FE +L I+ N + + M +H + T + G L +GIF +EA++KI+A+ + Y + W+I DFVVVV+ + M+L + ++S+ V LR LR RV R L++V ++ +L +II +M L IG L+ + I+AIIG+ Sbjct: 1114 FEVFILTVIMCN-MGMMMVQHYDQPPLTTVIGNYVL-----VGIFLLEAIIKIIAM-----RLHYFKKAWSIFDFVVVVSSIVGMYLGMS--TESAVVSPGLLRVLRVFRVARLLRVVQFAKRIRQLLVAIIISMPALFNIGTLLFLVMFIYAIIGMS 1258 HSP 7 Score: 67.781 bits (164), Expect = 6.650e-11 Identity = 75/292 (25.68%), Postives = 147/292 (50.34%), Query Frame = 2 Query: 1880 TKSMKGNIFIRSYAGIRRRRKERCTSFWRTEKHFRFSVRRLVKSQPFYWAVIILVFFNTVCVAIEHYEQGKWLTLFLNYAEYVFLCLFMMEMMIKMYGLSIRVYFQSSFNIFDCVVIAGSLFEIIYGIFVQDSSFG---LSVLRALRLLRIFKVTRYWAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXGMQLFGGEFNFEEGKPPQNFDTFVKALLTVFQILTGEDWNTVM-------------YNGIQSKGGVKERGTVFSIYFVLLVVFGNYTLLNVFLAIAVDNL 2707 T+S + + I A R+ R R FR + LV S F ++ ++ N + ++HY+Q T+ NY V + +F++E +IK+ + + YF+ +++IFD VV+ S+ + G+ + + L VLR R+ R+ +V ++ +R L+++++ SM ++ ++ LLFL + I+A++GM FG NF+TF +++ +F++ TG WN ++ + G+ + G VF Y V +V ++N+++A+ +DN+ Sbjct: 1072 TESQRKWVQILMAAAKRKPPSNRL----RPTDCFRGKLFDLVSSNQFEVFILTVIMCNMGMMMVQHYDQPPLTTVIGNY---VLVGIFLLEAIIKIIAMRLH-YFKKAWSIFDFVVVVSSIVGMYLGMSTESAVVSPGLLRVLRVFRVARLLRVVQFAKRIRQLLVAIIISMPALFNIGTLLFLVMFIYAIIGMSSFGNIKKQGALNDLVNFETFSSSIILIFRLGTGTGWNDILDALVVQPPHCDPNFGGLPNGNCGFPIGAVF--YLVTYIVSVFLIIVNMYIAVLLDNV 1353 HSP 8 Score: 61.6178 bits (148), Expect = 4.367e-9 Identity = 61/261 (23.37%), Postives = 116/261 (44.44%), Query Frame = 2 Query: 4160 FEYFIMVMIALNTLILMMKYYREEKKASSAATHDREQQAYLNYCNTLIFLNSAFTVMFSIECVLKIMAFGPKNYFRDPWNIFDFITVIGSITDVLVSELQDXXXXXXXXXXXXXXXXXXXXXXQGY-TIRILLWTFIQSFKALPYVCLLIAMLFFIYSIIGMQVFG---NIKLISEYQINRHNNFQTFTNGLLLLFRCATGESWQEIMLACDNNKPCEKDIENTNNFDCGSNFTYIYFVSFIFLCSFLMLNLFVAVIMDNF 4930 F+ I +I LNT++L M Y+ + L LN+ FT +F +E ++KI AFG Y + WN+FD + +I S + + + + L Q + T+ L+ S + + ++ ++ ++++++GM+VFG + I R NF FT+ +++FR E W E + C + NT ++F+ + + +F++LNLFVA+++++F Sbjct: 482 FDGIIAGLILLNTVVLTMYYHGMPDDLTFV----------------LDILNAIFTGLFILEMIVKIFAFGLVKYICNKWNLFDSVIIITSAVAYFLGT------STGVSIFRILRLLRVLYLAQSWETMAKLIRAIAHSVDPIFNITCILGVIIYVFAVVGMRVFGPHYTAEAFGSRGIPRW-NFTDFTHSFMMVFRILCSE-WVEPLWDC-------MRVTNTA--------ALLFFLPALIVGNFIVLNLFVALLLNSF 703 HSP 9 Score: 57.7658 bits (138), Expect = 6.351e-8 Identity = 40/160 (25.00%), Postives = 76/160 (47.50%), Query Frame = 2 Query: 3251 ILEFFDYAFTGVFTVEMILKIIDLGIILHPGSYCRDLWNILDATVVICALVAFIMGQKPSPTGNKLRGSSAKNLNTIKSLRVLRVLRPLKTINRVPKLKAVFDCVVSSLKNVFNILIVYILFQFIFAVIAVQLFQGKFFYCNDASKSSRETCRGYFFDYA 3730 +L+ + FTG+F +EMI+KI G++ Y + WN+ D+ ++I + VA+ +G + TG + R+LR+LR L + + + S+ +FNI + + ++FAV+ +++F + + SR R F D+ Sbjct: 511 VLDILNAIFTGLFILEMIVKIFAFGLV----KYICNKWNLFDSVIIITSAVAYFLG---TSTG-------------VSIFRILRLLRVLYLAQSWETMAKLIRAIAHSVDPIFNITCILGVIIYVFAVVGMRVFGPHY---TAEAFGSRGIPRWNFTDFT 647
BLAST of Voltage dependent L type calcium channel subunit vs. Ensembl Nematostella
Match: EDO35497 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SLD1]) HSP 1 Score: 194.512 bits (493), Expect = 1.939e-52 Identity = 154/554 (27.80%), Postives = 286/554 (51.62%), Query Frame = 2 Query: 3143 VVNLRYFDLFIMIVICASSIALAAEDP-VKEKSLKNNILEFFDYAFTGVFTVEMILKIIDLGIILHPGSYCRDLWNILDATVVICALVAFIMGQKPSPTGNKLRGSSAKNLNTIKSLRVLRVLRPLKTINRVPKLKAVFDCVVSSLKNVFNILIVYILFQFIFAVIAVQLFQGKFFYC-NDASKSSRETCRGYFFDYAGRSTPETKKRLWQHHDFHFDNILYAMLTLFTVTTGEGWPTVLKNSMESTNIDNGPIADYRQEMAXXXXXXXXXXXXXXXXXXXALIIITFQEQGENELIDLDLDKNQKQCIDFAINEKPLCRYMPKDKTTIKYRVWRLVVSTPFEYFIMVMIALNTLILMMKYYREEKKASSAATHDREQQAYLNYCNTLIFLNSAFTVMFSIECVLKIMAFGPKNYFRDPWNIFDFITVIGSITDVL------VSELQDXXXXXXXXXXXXXXXXXXXXXXQGYTIRILLWTFIQSFKALPYVCLLIAMLFFIYSIIGMQVFGNIKLISEYQ---INRHNNFQTFTNGLLLLFRCATGESWQEIM 4771 V + R FD I++ I S LA E P + E+ LK I++ FT +FT+EM++K++ +G++L PG+Y RD W++LD +V+ + + I+ S + L T++ R LR LRPL+ I R P LK V ++ SLK + N +++ +F +F ++ VQLF+GKF+YC D+ S++ C + + W + ++FD++L A+++LF V+T +GW ++ + +++ ++D PI +Y + +++I F ++ F +N+ V +++ FQ E +D + + A N+ Y + ++ ++ + ++ I +I +N + + +++Y+ Q ++ N FT +F IE V+K++A G Y +D WN+ D V+ S+T ++ V L + + + + + L +G +R LL T ++ +P + LL +LFFIYS +G+Q+FG+++ +Y NRH +F+ F +L LFR ATG++W I+ Sbjct: 15 VCSHRAFDYVILVFIIFSCAVLAIEAPDIAEQGLKRQIIDISMLVFTIIFTIEMLIKLVAMGLVLGPGTYLRDGWDVLDGFLVMVSWIDIIVTYTSH--------VSPEVLGTLRVFRALRTLRPLRVIRRAPGLKLVVQTLLYSLKPIGNTVLIAAIFFVMFGILGVQLFKGKFYYCEGDSHVISKQEC------------ANSTRGQWVNRRYNFDDLLQALISLFVVSTKDGWVEIMHHGIDAVDVDVQPIVNYAEWRLVYFIPFLLLGGFLVLNMIVGVVVENFQRCRER--MDEEEQARPHRKGKKARNQMQDSLYY-ESYGPLRLKIHFICTHRNWDITIAAIICINVICMSLEHYKMP-------------QVFVETTNYF------FTSVFVIEVVVKVIALGFVRYPKDRWNLIDLAIVLLSVTGIVLELLVKVDHLFNPTVIRTLRVLRITRVLKLVKLAKG--VRSLLDTLFEALPQVPNLGLLFFLLFFIYSCLGIQLFGSLECSHDYPCQGFNRHAHFRDFGTAMLTLFRIATGDNWNGIL 524 HSP 2 Score: 111.309 bits (277), Expect = 6.423e-25 Identity = 80/301 (26.58%), Postives = 157/301 (52.16%), Query Frame = 2 Query: 734 RKYAKIIIEWGPFEYMVLLTILANCIVLSMERHLPKKDKTLLAGQL-ELTEKYFLGIFCVEALLKIVALGFCCHKEAYLRNVWNIMDFVVVVTGFLMMFLNIDNHSDSSTVD-LRTLRAVRVLRPLKLVAGFPSLQVVLKSIIRAMAPLLQIGLLVLFAITIFAIIGLEFYSGAFHYTCFKANSDKLPLPIPTEKSLVPCSNSKNGSGLGAYTCPEDYQCKAYWEGPNYGITSFDNIGYAMLTVFQCITMEGWTDIMYHTNDAIG-------NRFNW--LYFVPLIILGSFFMLNLVLGVL 1603 R+ + + F+Y++L+ I+ +C VL++E P + L Q+ +++ F IF +E L+K+VA+G YLR+ W+++D +V+ ++ + + +H + LR RA+R LRPL+++ P L++V+++++ ++ P+ L+ +F I+G++ + G F+Y + +S + S C+NS G W Y +FD++ A++++F T +GW +IM+H DA+ N W +YF+P ++LG F +LN+++GV+ Sbjct: 9 RQRMRAVCSHRAFDYVILVFIIFSCAVLAIEA--PDIAEQGLKRQIIDISMLVFTIIFTIEMLIKLVAMGLVLGPGTYLRDGWDVLDGFLVMVSWIDIIVTYTSHVSPEVLGTLRVFRALRTLRPLRVIRRAPGLKLVVQTLLYSLKPIGNTVLIAAIFFVMFGILGVQLFKGKFYYC--EGDSHVI--------SKQECANSTRGQ----------------WVNRRY---NFDDLLQALISLFVVSTKDGWVEIMHHGIDAVDVDVQPIVNYAEWRLVYFIPFLLLGGFLVLNMIVGVV 278 HSP 3 Score: 71.2478 bits (173), Expect = 2.906e-12 Identity = 64/252 (25.40%), Postives = 118/252 (46.83%), Query Frame = 2 Query: 3104 FSPLNSLRRFCHFVVNLRYFDLFIMIVICASSIALAAEDPVKEKSLKNNILEFFDYAFTGVFTVEMILKIIDLGIILHPGSYCRDLWNILDATVVICALVAFIMGQKPSPTGNKLRGSSAKNLNTIKSLRVLRVLRPLKTINRVPKLKAVFDCVVSSLKNVFNILIVYILFQFIFAVIAVQLFQGKFFYCNDASKSSRETCRGYFFDYAGRSTPETKKRLWQHHDFHFDNILYAMLTLFTVTTGEGWPTVLK 3859 + LR HF+ R +D+ I +IC + I ++ E + +E +Y FT VF +E+++K+I LG + +P +D WN++D +V+ ++ ++ ++ N I++LRVLR+ R LK + ++++ D + +L V N+ +++ L FI++ + +QLF S C+G+ + HF + AMLTLF + TG+ W +LK Sbjct: 314 YESYGPLRLKIHFICTHRNWDITIAAIICINVICMSLE----HYKMPQVFVETTNYFFTSVFVIEVVVKVIALGFVRYP----KDRWNLIDLAIVLLSVTGIVLELL-------VKVDHLFNPTVIRTLRVLRITRVLKLVKLAKGVRSLLDTLFEALPQVPNLGLLFFLLFFIYSCLGIQLF-------GSLECSHDYPCQGF------------------NRHAHFRDFGTAMLTLFRIATGDNWNGILK 525 HSP 4 Score: 70.8626 bits (172), Expect = 3.998e-12 Identity = 63/229 (27.51%), Postives = 118/229 (51.53%), Query Frame = 2 Query: 4316 AFTVMFSIECVLKIMA----FGPKNYFRDPWNIFDFITVIGSITDVLV---SELQDXXXXXXXXXXXXXXXXXXXXXXQGYTIRILLWTFIQSFKALPYVCLLIAMLFFIYSIIGMQVF--------GNIKLISEYQ---------INRHNNFQTFTNGLLLLFRCATGESWQEIMLACDNNKPCEKDIENTNNFDCGSNFTYIYFVSFIFLCSFLMLNLFVAVIMDNF 4930 FT++F+IE ++K++A GP Y RD W++ D V+ S D++V S + +L R R R ++++R+ +++++ T + S K + L+ A+ F ++ I+G+Q+F G+ +IS+ + +NR NF L+ LF +T + W EIM + D++ N+ + + +YF+ F+ L FL+LN+ V V+++NF Sbjct: 59 VFTIIFTIEMLIKLVAMGLVLGPGTYLRDGWDVLDGFLVMVSWIDIIVTYTSHVSPEVLGTLRVFRALRTLRPLRVIRRAPGLKLVVQTLLYSLKPIGNTVLIAAIFFVMFGILGVQLFKGKFYYCEGDSHVISKQECANSTRGQWVNRRYNFDDLLQALISLFVVSTKDGWVEIM--HHGIDAVDVDVQPIVNY---AEWRLVYFIPFLLLGGFLVLNMIVGVVVENF 282 HSP 5 Score: 56.9954 bits (136), Expect = 8.708e-8 Identity = 60/238 (25.21%), Postives = 107/238 (44.96%), Query Frame = 2 Query: 794 ILANCIVLSMERHLPKKDKTLLAGQLELTEKYFLGIFCVEALLKIVALGFCCHKEAYLRNVWNIMDFVVV---VTGFLMMFLNIDNHSDSSTVDLRTLRAVRVLRPLKLVAGFPSLQVVLKSIIRAMAPLLQIGLLVLFAITIFAIIGLEFYSGAFHYTCFKANSDKLPLPIPTEKSLVPCSNSKNGSGLGAYTCPEDYQCKAYWEGPNYGITSFDNIGYAMLTVFQCITMEGWTDIM 1498 I N I +S+E + K + + E T +F +F +E ++K++ALGF Y ++ WN++D +V VTG ++ L +H + TV +RTLR +R+ R LKLV ++ +L ++ A+ + +GLL I++ +G++ + G+ C DY C+ + + F + G AMLT+F+ T + W I+ Sbjct: 341 ICINVICMSLEHY--KMPQVFV----ETTNYFFTSVFVIEVVVKVIALGFV----RYPKDRWNLIDLAIVLLSVTGIVLELLVKVDHLFNPTV-IRTLRVLRITRVLKLVKLAKGVRSLLDTLFEALPQVPNLGLLFFLLFFIYSCLGIQLF--------------------------------------GSLECSHDYPCQGFNRHAH-----FRDFGTAMLTLFRIATGDNWNGIL 524 HSP 6 Score: 51.2174 bits (121), Expect = 4.732e-6 Identity = 59/231 (25.54%), Postives = 121/231 (52.38%), Query Frame = 2 Query: 1922 GIRRRRKERCTSFWRTEKHFRFSVRRLVKSQPFYWAVIILVFFNTVCVAIEHYEQGKWLTLFLNYAEYVFLCLFMMEMMIKMYGLSIRVYFQSSFNIFDCVVIAGSLFEIIYGIFVQ-DSSFGLSVLRALRLLRI---FKVTRYWAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXGMQLFGGEFNFEEGKPPQNFD------TFVKALLTVFQILTGEDWNTVMYNG 2584 G + R + + + ++ + R + + + + + ++ N +C+++EHY+ + +F+ Y F +F++E+++K+ L Y + +N+ D ++ S+ I+ + V+ D F +V+R LR+LRI K+ + +R+L+ +L ++ + +L L FL I++ LG+QLFG P Q F+ F A+LT+F+I TG++WN ++ G Sbjct: 301 GKKARNQMQDSLYYESYGPLRLKIHFICTHRNWDITIAAIICINVICMSLEHYKMPQ---VFVETTNYFFTSVFVIEVVVKVIALGFVRYPKDRWNLIDLAIVLLSVTGIVLELLVKVDHLFNPTVIRTLRVLRITRVLKLVKLAKGVRSLLDTLFEALPQVPNLGLLFFLLFFIYSCLGIQLFG-SLECSHDYPCQGFNRHAHFRDFGTAMLTLFRIATGDNWNGILKVG 527
BLAST of Voltage dependent L type calcium channel subunit vs. Ensembl Medaka
Match: cacna1c (voltage-dependent L-type calcium channel subunit alpha-1C [Source:NCBI gene;Acc:101173517]) HSP 1 Score: 1234.94 bits (3194), Expect = 0.000e+0 Identity = 746/1598 (46.68%), Postives = 1014/1598 (63.45%), Query Frame = 2 Query: 704 LFIFSEENVIRKYAKIIIEWGPFEYMVLLTILANCIVLSMERHLPKKDKTLLAGQLELTEKYFLGIFCVEALLKIVALGFCCHKEAYLRNVWNIMDFVVVVTGFLMMFLNIDNHSDSST--------VDLRTLRAVRVLRPLKLVAGFPSLQVVLKSIIRAMAPLLQIGLLVLFAITIFAIIGLEFYSGAFHYTCFKANSDKLPLPIPTEKSLVPCSNSKNGSGLGAYTCPEDYQCKAYWEGPNYGITSFDNIGYAMLTVFQCITMEGWTDIMYHTNDAIGNRFNWLYFVPLIILGSFFMLNLVLGVLSGXXXXXXXXXXXXXXXLKLRRQQQTEKEFNGYMEWIQKAEEV-LLNEATTTSEDKMRIIAARRRAEKQKYKLLGKNQSIPDFEYEDTELYSETKSMKGNIFIRSYAGIRRRRKERCTSFWRTEKHFRFSVRRLVKSQPFYWAVIILVFFNTVCVAIEHYEQGKWLTLFLNYAEYVFLCLFMMEMMIKMYGLSIRVYFQSSFNIFDCVVIAGSLFEIIYGIFVQDSSFGLSVLRALRLLRIFKVTRYWAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXGMQLFGGEFNFEEGKPPQNFDTFVKALLTVFQILTGEDWNTVMYNGIQSKGGVKERGTVFSIYFVLLVVFGNYTLLNVFLAIAVDNLANXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSSDNFIGRLPLSIDPPMVQVCPPSPQTANSLISKNFSFDHNQVEVNDKGCLLNTNK---PNGKLGMLGHDNTNFNSLESDPVPNKIEPETIQRK--PVLPYSAMFIFSPLNSLRRFCHFVVNLRYFDLFIMIVICASSIALAAEDPVKEKSLKNNILEFFDYAFTGVFTVEMILKIIDLGIILHPGSYCRDLWNILDATVVICALVAFIMGQKPSPTGNKLRGSSAKNLNTIKSLRVLRVLRPLKTINRVPKLKAVFDCVVSSLKNVFNILIVYILFQFIFAVIAVQLFQGKFFYCNDASKSSRETCRGYFFDY--AGRSTPETKKRLWQHHDFHFDNILYAMLTLFTVTTGEGWPTVLKNSMESTNIDNGPIADYRQEMAXXXXXXXXXXXXXXXXXXXALIIITFQEQGENELIDLDLDKNQKQCIDFAINEKPLCRYMPKDKTTIKYRVWRLVVSTPFEYFIMVMIALNTLILMMKYYREEKKASSAATHDREQQAYLNYCNTLIFLNSAFTVMFSIECVLKIMAFGPKNYFRDPWNIFDFITVIGSITDVLVSEL------QDXXXXXXXXXXXXXXXXXXXXXXQGYTIRILLWTFIQSFKALPYVCLLIAMLFFIYSIIGMQVFGNIKLISEYQINRHNNFQTFTNGLLLLFRCATGESWQEIMLACDNNKPCEKDIENTNNF---DCGSNFTYIYFVSFIFLCSFLMLNLFVAVIMDNFDYLTRDSSILGPHHLDEYIRVWAEYDPGAIGRIHHSEMYEMLRNMEPPVGFGKKCPYRLAYRKLIRMNMPVDENGTVNFTTTLFALIRESLNIKMSTAEYMDIKDMELRQTICKMWPVQAKKKLNLIVPPDSELVFHKMTVGKIYAGYLIVENWRAYKNSQEQG 5422 L + +N IR+ I+EW PFE ++L+TI ANC+ L++ P+ D LE E FL IF VEA LK++A G H AYLRN WN++DF++VV G L D +T D++ LRA RVLRPL+LV+G PSLQVVL SII+AM PLL I LLVLF I I+AIIGLE + G H TC ++ + E+ PC+ G + QC+ WEGPN GIT+FDN +AMLTVFQCITMEGWTD++Y NDA+ R+ W+YFV LII+GSFF+LNLVLGVLSGEF+KERE+ + R F KLR +QQ E++ GY++WI +AE++ NE +DK R ++ +N+S+ ++ ET + + IR I + + R + W + FR R VKSQ FYW VI LVF NT+ +A EH+ Q +WLT + A V L LF EM++KMY L ++ YF S FN FD V+ G + E I S G+SVLR +RLLRIFK+TRYW SL NLV SLLNS+RSI SLL LLFLFI+IF+LLGMQLFGG+FNF+E + FD F ++LLTVFQILTGEDWN+VMY+GI + GG G + IYF++L + GNY LLNVFLAIAVDNLA+A+ LT+A++E+ +R A ++ + PP+ + + S+ S + ++ ++D C + N+ P +G D+ + P P + ++ K P+ A F+FS N R CH +VN F I+ I SSI+LAAEDPVK S +N IL + D+ FTG+FT+E+ILK+ G LH GS+CR+ +NILD VV +L++ G + +N +K LRVLRVLRPL+ INR LK V CV +++ + NI+IV L QF+FA I VQLF+GKFFYC D+SK ++ CRG + Y P R+W++ DF+FD++L M+ LF V+T EGWP +L +++S + D GPI +YR ++IF+I++ I+ FF +NIFV +I+TFQEQGE E + +LDKNQ+QC+++A+ +PL RY+PK+ +Y+VW +V ST FEY + +I LNT+ L M+++ + K N+ + + LN FT +F++E +LK++AF P+ YF DPWN+FDF+ VIGSI DV++SE+ ++++ +S+ F RLFR RL+KLL +G IR LLWTFI+SF+ALPYV LLI MLFFIY++IGMQ+FG I L QINR+NNFQTF +LLLFRCATGE+WQEIMLAC N+PCEK N N+ +CGS F IYFVSF LC+FL++NLFVAVIMDNFDYLTRD SILGPHHLDE+ R+WAEYDP A GRI H ++ +LR ++PP+GFGK CP+R+A ++L+ MNMP++ +GTV F TLFAL+R +L IK T ++ + ELR + K+W + K L+ +VPP + ++TVGK YA +LI E +R +K +EQG Sbjct: 143 LLCLTLKNPIRRACISIVEWKPFEIIILMTIFANCVALAVYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIAYGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKGDGATPIGGKAAGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCVHNHTG-----LNAEEKPAPCAPD---GAYGRHCTQNGTQCRVGWEGPNDGITNFDNFAFAMLTVFQCITMEGWTDVLYWVNDAVDYRWPWVYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGDFQKLREKQQLEEDLKGYLDWITQAEDIDPENEEEGLDDDKPRNLSMP----------ASENESVNTDNPPGGDVEGETCCTR--LAIR----ISKSKFSRYSRRW--NRLFRRKCRAAVKSQVFYWLVIFLVFLNTLTIASEHHRQPQWLTDVQDIANKVLLALFTGEMLLKMYSLGLQAYFVSLFNRFDSFVVCGGILETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDETRR-STFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYGGPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEAKERKKLARLASPKKHEENE---------KPPLEEKKSEKIEL-KSITSDGETNPATKISMDD--CCGDENEEKNPYPANDYIGDDDEEEPEMPVGPRPRPLSDIHLKEKAVPMPEARAFFVFSHTNKFRVLCHKIVNHNIFTNLILFFILLSSISLAAEDPVKNDSFRNQILGYADHVFTGLFTIEIILKMTAYGAFLHKGSFCRNYFNILDLVVVSVSLIS--------------SGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKFFYCTDSSKQTQAECRGSYIMYKDGDVGKPGRSPRVWENSDFNFDDVLQGMMALFAVSTFEGWPGLLYRAIDSHSEDVGPIYNYRVVISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLRRYIPKNP--YQYKVWYVVNSTYFEYLMFTLILLNTICLAMQHHGQTK----------------NFNDAMNILNMLFTGLFTVEMILKLIAFKPRGYFSDPWNVFDFLIVIGSIIDVILSEINGLQNSEENARISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQMFGKIALRDLSQINRNNNFQTFPQAVLLLFRCATGEAWQEIMLACSPNRPCEKGSTNENSTASEECGSQFAIIYFVSFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRIK--TDGNLEQANEELRAIVKKIWKRTSMKLLDQVVPPAGD---DEVTVGKFYATFLIQEYFRKFKKRKEQG 1664 HSP 2 Score: 89.3521 bits (220), Expect = 6.043e-17 Identity = 75/291 (25.77%), Postives = 134/291 (46.05%), Query Frame = 2 Query: 659 INLSFPGMQTSTSKSLFIFSEENVIRKYAKIIIEWGPFEYMVLLTILANCIVLSMERHLPKKDKTLLAGQLELTEKYFLGIFCVEALLKIVALGFCCHKEAYLRNVWNIMDFVVVVTGFLMMFLNIDNHSDSSTVD-LRTLRAVRVLRPLKLVAGFPSLQVVLKSIIRAMAPLLQIGLLVLFAITIFAIIGLEFYSGAFHYTCFKANSDKLPLPIPTEKSLVPCSNS----KNGSGLGAYTCPEDYQCKAYWEGPNYGITSFDNIGYAMLTVFQCITMEGWTDIMYHTNDA 1516 I+L + +++ F+FS N R I+ F ++L IL + I L+ E P K+ + L + F G+F +E +LK+ A G HK ++ RN +NI+D VVV + + SS ++ ++ LR +RVLRPL+ + L+ V++ + A+ + I ++ +FA IG++ + G F Y C + ++++ C S K+G P WE ++ +FD++ M+ +F T EGW ++Y D+ Sbjct: 900 IHLKEKAVPMPEARAFFVFSHTNKFRVLCHKIVNHNIFTNLILFFILLSSISLAAED--PVKNDSFRNQILGYADHVFTGLFTIEIILKMTAYGAFLHKGSFCRNYFNILDLVVVSVSLISSGIQ------SSAINVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKFFY-CTDS----------SKQTQAECRGSYIMYKDGDVGKPGRSPR------VWENSDF---NFDDVLQGMMALFAVSTFEGWPGLLYRAIDS 1162
BLAST of Voltage dependent L type calcium channel subunit vs. Ensembl Medaka
Match: cacna1c (voltage-dependent L-type calcium channel subunit alpha-1C [Source:NCBI gene;Acc:101173517]) HSP 1 Score: 1225.31 bits (3169), Expect = 0.000e+0 Identity = 745/1609 (46.30%), Postives = 1012/1609 (62.90%), Query Frame = 2 Query: 704 LFIFSEENVIRKYAKIIIEWGPFEYMVLLTILANCIVLSMERHLPKKDKTLLAGQLELTEKYFLGIFCVEALLKIVALGFCCHKEAYLRNVWNIMDFVVVVTGFLMMFLNIDNHSDSST--------VDLRTLRAVRVLRPLKLVAGFPSLQVVLKSIIRAMAPLLQIGLLVLFAITIFAIIGLEFYSGAFHYTCFKANSDKLPLPIPTEKSLVPCSNSKNGSGLGAYTCPEDYQCKAYWEGPNYGITSFDNIGYAMLTVFQCITMEGWTDIMYHTNDAIGNRFNWLYFVPLIILGSFFMLNLVLGVLSGXXXXXXXXXXXXXXXLKLRRQQQTEKEFNGYMEWIQKAEEV-LLNEATTTSEDKMR-----IIAARRRAEKQKYKLLGKNQSIPDFEYEDTELYS------ETKSMKGNIFIRSYAGIRRRRKERCTSFWRTEKHFRFSVRRLVKSQPFYWAVIILVFFNTVCVAIEHYEQGKWLTLFLNYAEYVFLCLFMMEMMIKMYGLSIRVYFQSSFNIFDCVVIAGSLFEIIYGIFVQDSSFGLSVLRALRLLRIFKVTRYWAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXGMQLFGGEFNFEEGKPPQNFDTFVKALLTVFQILTGEDWNTVMYNGIQSKGGVKERGTVFSIYFVLLVVFGNYTLLNVFLAIAVDNLANXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSSDNFIGRLPLSIDPPMVQVCPPSPQTANSLISKNFSFDHNQVEVNDKGCLLNTNK---PNGKLGMLGHDNTNFNSLESDPVPNKIEPETIQRK--PVLPYSAMFIFSPLNSLRRFCHFVVNLRYFDLFIMIVICASSIALAAEDPVKEKSLKNNILEFFDYAFTGVFTVEMILKIIDLGIILHPGSYCRDLWNILDATVVICALVAFIMGQKPSPTGNKLRGSSAKNLNTIKSLRVLRVLRPLKTINRVPKLKAVFDCVVSSLKNVFNILIVYILFQFIFAVIAVQLFQGKFFYCNDASKSSRETCRGYFFDY--AGRSTPETKKRLWQHHDFHFDNILYAMLTLFTVTTGEGWPTVLKNSMESTNIDNGPIADYRQEMAXXXXXXXXXXXXXXXXXXXALIIITFQEQGENELIDLDLDKNQKQCIDFAINEKPLCRYMPKDKTTIKYRVWRLVVSTPFEYFIMVMIALNTLILMMKYYREEKKASSAATHDREQQAYLNYCNTLIFLNSAFTVMFSIECVLKIMAFGPKNYFRDPWNIFDFITVIGSITDVLVSEL------QDXXXXXXXXXXXXXXXXXXXXXXQGYTIRILLWTFIQSFKALPYVCLLIAMLFFIYSIIGMQVFGNIKLISEYQINRHNNFQTFTNGLLLLFRCATGESWQEIMLACDNNKPCEKDIENTNNF---DCGSNFTYIYFVSFIFLCSFLMLNLFVAVIMDNFDYLTRDSSILGPHHLDEYIRVWAEYDPGAIGRIHHSEMYEMLRNMEPPVGFGKKCPYRLAYRKLIRMNMPVDENGTVNFTTTLFALIRESLNIKMSTAEYMDIKDMELRQTICKMWPVQAKKKLNLIVPPDSELVFHKMTVGKIYAGYLIVENWRAYKNSQEQG 5422 L + +N IR+ I+EW PFE ++L+TI ANC+ L++ P+ D LE E FL IF VEA LK++A G H AYLRN WN++DF++VV G L D +T D++ LRA RVLRPL+LV+G PSLQVVL SII+AM PLL I LLVLF I I+AIIGLE + G H TC ++ + E+ PC+ G + QC+ WEGPN GIT+FDN +AMLTVFQCITMEGWTD++Y DA+G W+YFV L+I GSFF+LNLVLGVLSGEF+KERE+ + R F KLR +QQ E++ GY++WI +AE++ NE +DK R + R A K+ L K S+P E E + E ++ + IR I + + R + W + FR R VKSQ FYW VI LVF NT+ +A EH+ Q +WLT + A V L LF EM++KMY L ++ YF S FN FD V+ G + E I S G+SVLR +RLLRIFK+TRYW SL NLV SLLNS+RSI SLL LLFLFI+IF+LLGMQLFGG+FNF+E + FD F ++LLTVFQILTGEDWN+VMY+GI + GG G + IYF++L + GNY LLNVFLAIAVDNLA+A+ LT+A++E+ +R A ++ + PP+ + + S+ S + ++ ++D C + N+ P +G D+ + P P + ++ K P+ A F+FS N R CH +VN F I+ I SSI+LAAEDPVK S +N IL + D+ FTG+FT+E+ILK+ G LH GS+CR+ +NILD VV +L++ G + +N +K LRVLRVLRPL+ INR LK V CV +++ + NI+IV L QF+FA I VQLF+GKFFYC D+SK ++ CRG + Y P R+W++ DF+FD++L M+ LF V+T EGWP +L +++S + D GPI +YR ++IF+I++ I+ FF +NIFV +I+TFQEQGE E + +LDKNQ+QC+++A+ +PL RY+PK+ +Y+VW +V ST FEY + +I LNT+ L M+++ + K N+ + + LN FT +F++E +LK++AF P++YF D WN FD + V+GSI D+ ++E+ ++++ +S+ F RLFR RL+KLL +G IR LLWTFI+SF+ALPYV LLI MLFFIY++IGMQ+FG I L QINR+NNFQTF +LLLFRCATGE+WQEIMLAC N+PCEK N N+ +CGS F IYFVSF LC+FL++NLFVAVIMDNFDYLTRD SILGPHHLDE+ R+WAEYDP A GRI H ++ +LR ++PP+GFGK CP+R+A ++L+ MNMP++ +GTV F TLFAL+R +L IK T ++ + ELR + K+W + K L+ +VPP + ++TVGK YA +LI E +R +K +EQG Sbjct: 165 LLCLTLKNPIRRACISIVEWKPFEIIILMTIFANCVALAVYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIAYGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKGDGATPIGGKAAGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCVHNHTG-----LNAEEKPAPCAPD---GAYGRHCTQNGTQCRVGWEGPNDGITNFDNFAFAMLTVFQCITMEGWTDVLYWMQDAMGYELPWVYFVSLVIFGSFFVLNLVLGVLSGEFSKEREKAKARGDFQKLREKQQLEEDLKGYLDWITQAEDIDPENEEEGLDDDKPRNRKNHHFLSLRGAVKKNAAFLRKALSMPASENESVNTDNPPGGDVEGETCCTRLAIR----ISKSKFSRYSRRW--NRLFRRKCRAAVKSQVFYWLVIFLVFLNTLTIASEHHRQPQWLTDVQDIANKVLLALFTGEMLLKMYSLGLQAYFVSLFNRFDSFVVCGGILETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDETRR-STFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYGGPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEAKERKKLARLASPKKHEENE---------KPPLEEKKSEKIEL-KSITSDGETNPATKISMDD--CCGDENEEKNPYPANDYIGDDDEEEPEMPVGPRPRPLSDIHLKEKAVPMPEARAFFVFSHTNKFRVLCHKIVNHNIFTNLILFFILLSSISLAAEDPVKNDSFRNQILGYADHVFTGLFTIEIILKMTAYGAFLHKGSFCRNYFNILDLVVVSVSLIS--------------SGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKFFYCTDSSKQTQAECRGSYIMYKDGDVGKPGRSPRVWENSDFNFDDVLQGMMALFAVSTFEGWPGLLYRAIDSHSEDVGPIYNYRVVISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLRRYIPKNP--YQYKVWYVVNSTYFEYLMFTLILLNTICLAMQHHGQTK----------------NFNDAMNILNMLFTGLFTVEMILKLIAFKPRHYFVDAWNTFDALIVVGSIVDIAITEVNGLQNSEENARISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQMFGKIALRDLSQINRNNNFQTFPQAVLLLFRCATGEAWQEIMLACSPNRPCEKGSTNENSTASEECGSQFAIIYFVSFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRIK--TDGNLEQANEELRAIVKKIWKRTSMKLLDQVVPPAGD---DEVTVGKFYATFLIQEYFRKFKKRKEQG 1709 HSP 2 Score: 88.9669 bits (219), Expect = 7.295e-17 Identity = 75/291 (25.77%), Postives = 134/291 (46.05%), Query Frame = 2 Query: 659 INLSFPGMQTSTSKSLFIFSEENVIRKYAKIIIEWGPFEYMVLLTILANCIVLSMERHLPKKDKTLLAGQLELTEKYFLGIFCVEALLKIVALGFCCHKEAYLRNVWNIMDFVVVVTGFLMMFLNIDNHSDSSTVD-LRTLRAVRVLRPLKLVAGFPSLQVVLKSIIRAMAPLLQIGLLVLFAITIFAIIGLEFYSGAFHYTCFKANSDKLPLPIPTEKSLVPCSNS----KNGSGLGAYTCPEDYQCKAYWEGPNYGITSFDNIGYAMLTVFQCITMEGWTDIMYHTNDA 1516 I+L + +++ F+FS N R I+ F ++L IL + I L+ E P K+ + L + F G+F +E +LK+ A G HK ++ RN +NI+D VVV + + SS ++ ++ LR +RVLRPL+ + L+ V++ + A+ + I ++ +FA IG++ + G F Y C + ++++ C S K+G P WE ++ +FD++ M+ +F T EGW ++Y D+ Sbjct: 945 IHLKEKAVPMPEARAFFVFSHTNKFRVLCHKIVNHNIFTNLILFFILLSSISLAAED--PVKNDSFRNQILGYADHVFTGLFTIEIILKMTAYGAFLHKGSFCRNYFNILDLVVVSVSLISSGIQ------SSAINVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKFFY-CTDS----------SKQTQAECRGSYIMYKDGDVGKPGRSPR------VWENSDF---NFDDVLQGMMALFAVSTFEGWPGLLYRAIDS 1207
BLAST of Voltage dependent L type calcium channel subunit vs. Ensembl Medaka
Match: cacna1c (voltage-dependent L-type calcium channel subunit alpha-1C [Source:NCBI gene;Acc:101173517]) HSP 1 Score: 1224.92 bits (3168), Expect = 0.000e+0 Identity = 745/1609 (46.30%), Postives = 1012/1609 (62.90%), Query Frame = 2 Query: 704 LFIFSEENVIRKYAKIIIEWGPFEYMVLLTILANCIVLSMERHLPKKDKTLLAGQLELTEKYFLGIFCVEALLKIVALGFCCHKEAYLRNVWNIMDFVVVVTGFLMMFLNIDNHSDSST--------VDLRTLRAVRVLRPLKLVAGFPSLQVVLKSIIRAMAPLLQIGLLVLFAITIFAIIGLEFYSGAFHYTCFKANSDKLPLPIPTEKSLVPCSNSKNGSGLGAYTCPEDYQCKAYWEGPNYGITSFDNIGYAMLTVFQCITMEGWTDIMYHTNDAIGNRFNWLYFVPLIILGSFFMLNLVLGVLSGXXXXXXXXXXXXXXXLKLRRQQQTEKEFNGYMEWIQKAEEV-LLNEATTTSEDKMR-----IIAARRRAEKQKYKLLGKNQSIPDFEYEDTELYS------ETKSMKGNIFIRSYAGIRRRRKERCTSFWRTEKHFRFSVRRLVKSQPFYWAVIILVFFNTVCVAIEHYEQGKWLTLFLNYAEYVFLCLFMMEMMIKMYGLSIRVYFQSSFNIFDCVVIAGSLFEIIYGIFVQDSSFGLSVLRALRLLRIFKVTRYWAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXGMQLFGGEFNFEEGKPPQNFDTFVKALLTVFQILTGEDWNTVMYNGIQSKGGVKERGTVFSIYFVLLVVFGNYTLLNVFLAIAVDNLANXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSSDNFIGRLPLSIDPPMVQVCPPSPQTANSLISKNFSFDHNQVEVNDKGCLLNTNK---PNGKLGMLGHDNTNFNSLESDPVPNKIEPETIQRK--PVLPYSAMFIFSPLNSLRRFCHFVVNLRYFDLFIMIVICASSIALAAEDPVKEKSLKNNILEFFDYAFTGVFTVEMILKIIDLGIILHPGSYCRDLWNILDATVVICALVAFIMGQKPSPTGNKLRGSSAKNLNTIKSLRVLRVLRPLKTINRVPKLKAVFDCVVSSLKNVFNILIVYILFQFIFAVIAVQLFQGKFFYCNDASKSSRETCRGYFFDY--AGRSTPETKKRLWQHHDFHFDNILYAMLTLFTVTTGEGWPTVLKNSMESTNIDNGPIADYRQEMAXXXXXXXXXXXXXXXXXXXALIIITFQEQGENELIDLDLDKNQKQCIDFAINEKPLCRYMPKDKTTIKYRVWRLVVSTPFEYFIMVMIALNTLILMMKYYREEKKASSAATHDREQQAYLNYCNTLIFLNSAFTVMFSIECVLKIMAFGPKNYFRDPWNIFDFITVIGSITDVLVSEL------QDXXXXXXXXXXXXXXXXXXXXXXQGYTIRILLWTFIQSFKALPYVCLLIAMLFFIYSIIGMQVFGNIKLISEYQINRHNNFQTFTNGLLLLFRCATGESWQEIMLACDNNKPCEKDIENTNNF---DCGSNFTYIYFVSFIFLCSFLMLNLFVAVIMDNFDYLTRDSSILGPHHLDEYIRVWAEYDPGAIGRIHHSEMYEMLRNMEPPVGFGKKCPYRLAYRKLIRMNMPVDENGTVNFTTTLFALIRESLNIKMSTAEYMDIKDMELRQTICKMWPVQAKKKLNLIVPPDSELVFHKMTVGKIYAGYLIVENWRAYKNSQEQG 5422 L + +N IR+ I+EW PFE ++L+TI ANC+ L++ P+ D LE E FL IF VEA LK++A G H AYLRN WN++DF++VV G L D +T D++ LRA RVLRPL+LV+G PSLQVVL SII+AM PLL I LLVLF I I+AIIGLE + G H TC ++ + E+ PC+ G + QC+ WEGPN GIT+FDN +AMLTVFQCITMEGWTD++Y DA+G W+YFV L+I GSFF+LNLVLGVLSGEF+KERE+ + R F KLR +QQ E++ GY++WI +AE++ NE +DK R + R A K+ L K S+P E E + E ++ + IR I + + R + W + FR R VKSQ FYW VI LVF NT+ +A EH+ Q +WLT + A V L LF EM++KMY L ++ YF S FN FD V+ G + E I S G+SVLR +RLLRIFK+TRYW SL NLV SLLNS+RSI SLL LLFLFI+IF+LLGMQLFGG+FNF+E + FD F ++LLTVFQILTGEDWN+VMY+GI + GG G + IYF++L + GNY LLNVFLAIAVDNLA+A+ LT+A++E+ +R A ++ + PP+ + + S+ S + ++ ++D C + N+ P +G D+ + P P + ++ K P+ A F+FS N R CH +VN F I+ I SSI+LAAEDPVK S +N IL + D+ FTG+FT+E+ILK+ G LH GS+CR+ +NILD VV +L++ G + +N +K LRVLRVLRPL+ INR LK V CV +++ + NI+IV L QF+FA I VQLF+GKFFYC D+SK ++ CRG + Y P R+W++ DF+FD++L M+ LF V+T EGWP +L +++S + D GPI +YR ++IF+I++ I+ FF +NIFV +I+TFQEQGE E + +LDKNQ+QC+++A+ +PL RY+PK+ +Y+VW +V ST FEY + +I LNT+ L M+++ + K N+ + + LN FT +F++E +LK++AF P++YF D WN FD + V+GSI D+ ++E+ ++++ +S+ F RLFR RL+KLL +G IR LLWTFI+SF+ALPYV LLI MLFFIY++IGMQ+FG I L QINR+NNFQTF +LLLFRCATGE+WQEIMLAC N+PCEK N N+ +CGS F IYFVSF LC+FL++NLFVAVIMDNFDYLTRD SILGPHHLDE+ R+WAEYDP A GRI H ++ +LR ++PP+GFGK CP+R+A ++L+ MNMP++ +GTV F TLFAL+R +L IK T ++ + ELR + K+W + K L+ +VPP + ++TVGK YA +LI E +R +K +EQG Sbjct: 165 LLCLTLKNPIRRACISIVEWKPFEIIILMTIFANCVALAVYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIAYGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKGDGATPIGGKAAGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCVHNHTG-----LNAEEKPAPCAPD---GAYGRHCTQNGTQCRVGWEGPNDGITNFDNFAFAMLTVFQCITMEGWTDVLYWMQDAMGYELPWVYFVSLVIFGSFFVLNLVLGVLSGEFSKEREKAKARGDFQKLREKQQLEEDLKGYLDWITQAEDIDPENEEEGLDDDKPRNRKNHHFLSLRGAVKKNAAFLRKALSMPASENESVNTDNPPGGDVEGETCCTRLAIR----ISKSKFSRYSRRW--NRLFRRKCRAAVKSQVFYWLVIFLVFLNTLTIASEHHRQPQWLTDVQDIANKVLLALFTGEMLLKMYSLGLQAYFVSLFNRFDSFVVCGGILETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDETRR-STFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYGGPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEAKERKKLARLASPKKHEENE---------KPPLEEKKSEKIEL-KSITSDGETNPATKISMDD--CCGDENEEKNPYPANDYIGDDDEEEPEMPVGPRPRPLSDIHLKEKAVPMPEARAFFVFSHTNKFRVLCHKIVNHNIFTNLILFFILLSSISLAAEDPVKNDSFRNQILGYADHVFTGLFTIEIILKMTAYGAFLHKGSFCRNYFNILDLVVVSVSLIS--------------SGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKFFYCTDSSKQTQAECRGSYIMYKDGDVGKPGRSPRVWENSDFNFDDVLQGMMALFAVSTFEGWPGLLYRAIDSHSEDVGPIYNYRVVISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLRRYIPKNP--YQYKVWYVVNSTYFEYLMFTLILLNTICLAMQHHGQTK----------------NFNDAMNILNMLFTGLFTVEMILKLIAFKPRHYFVDAWNTFDALIVVGSIVDIAITEVNGLQNSEENARISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQMFGKIALRDLSQINRNNNFQTFPQAVLLLFRCATGEAWQEIMLACSPNRPCEKGSTNENSTASEECGSQFAIIYFVSFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRIK--TDGNLEQANEELRAIVKKIWKRTSMKLLDQVVPPAGD---DEVTVGKFYATFLIQEYFRKFKKRKEQG 1709 HSP 2 Score: 88.9669 bits (219), Expect = 7.239e-17 Identity = 75/291 (25.77%), Postives = 134/291 (46.05%), Query Frame = 2 Query: 659 INLSFPGMQTSTSKSLFIFSEENVIRKYAKIIIEWGPFEYMVLLTILANCIVLSMERHLPKKDKTLLAGQLELTEKYFLGIFCVEALLKIVALGFCCHKEAYLRNVWNIMDFVVVVTGFLMMFLNIDNHSDSSTVD-LRTLRAVRVLRPLKLVAGFPSLQVVLKSIIRAMAPLLQIGLLVLFAITIFAIIGLEFYSGAFHYTCFKANSDKLPLPIPTEKSLVPCSNS----KNGSGLGAYTCPEDYQCKAYWEGPNYGITSFDNIGYAMLTVFQCITMEGWTDIMYHTNDA 1516 I+L + +++ F+FS N R I+ F ++L IL + I L+ E P K+ + L + F G+F +E +LK+ A G HK ++ RN +NI+D VVV + + SS ++ ++ LR +RVLRPL+ + L+ V++ + A+ + I ++ +FA IG++ + G F Y C + ++++ C S K+G P WE ++ +FD++ M+ +F T EGW ++Y D+ Sbjct: 945 IHLKEKAVPMPEARAFFVFSHTNKFRVLCHKIVNHNIFTNLILFFILLSSISLAAED--PVKNDSFRNQILGYADHVFTGLFTIEIILKMTAYGAFLHKGSFCRNYFNILDLVVVSVSLISSGIQ------SSAINVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKFFY-CTDS----------SKQTQAECRGSYIMYKDGDVGKPGRSPR------VWENSDF---NFDDVLQGMMALFAVSTFEGWPGLLYRAIDS 1207
BLAST of Voltage dependent L type calcium channel subunit vs. Ensembl Medaka
Match: cacna1c (voltage-dependent L-type calcium channel subunit alpha-1C [Source:NCBI gene;Acc:101173517]) HSP 1 Score: 1219.91 bits (3155), Expect = 0.000e+0 Identity = 744/1626 (45.76%), Postives = 1011/1626 (62.18%), Query Frame = 2 Query: 704 LFIFSEENVIRKYAKIIIEWGPFEYMVLLTILANCIVLSMERHLPKKDKTLLAGQLELTEKYFLGIFCVEALLKIVALGFCCHKEAYLRNVWNIMDFVVVVTGFLMMFLNIDNHSDSST--------VDLRTLRAVRVLRPLKLVAGFPSLQVVLKSIIRAMAPLLQIGLLVLFAITIFAIIGLEFYSGAFHYTCFKANSDKLPLPIPTEKSLVPCSNSKNGSGLGAYTCPEDYQCKAYWEGPNYGITSFDNIGYAMLTVFQCITMEGWTDIMYHTNDAIGNRFNWLYFVPLIILGSFFMLNLVLGVLSGXXXXXXXXXXXXXXXLKLRRQQQTEKEFNGYMEWIQKAEEV-LLNEATTTSEDKMRIIAARRRAEKQKYKLLGKNQSIPDFEYEDTELYSETKSMKGNIFIRSYAGIRRRRKERCTSFWRTEKHFRFSVRRLVKSQPFYWAVIILVFFNTVCVAIEHYEQGKWLTLFLNYAEYVFLCLFMMEMMIKMYGLSIRVYFQSSFNIFDCVVIAGSLFEIIYGIFVQDSSFGLSVLRALRLLRIFKVTRYWAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXGMQLFGGEFNFEEGKPPQNFDTFVKALLTVFQILTGEDWNTVMYNGIQSKGGVKERGTVFSIYFVLLVVFGNYTLLNVFLAIAVDNLANXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSSDNFIGRLPLSIDPPMVQVCPPSPQTANSLISKNFSFDHNQVEVNDKGCLLNTNK---PNGKLGMLGHDNTNFNSLESDPVPNKIEPETIQRK--PVLPYSAMFIFSPLNSLRRFCHFVVNLRYFDLFIMIVICASSIALAAEDPVKEKSLKNNILEFFDYAFTGVFTVEMILKIIDLGIILHPGSYCRDLWNILDATVVICALVAFIMGQKPSPTGNKLRGSSAKNLNTIKSLRVLRVLRPLKTINRVPKLKAVFDCVVSSLKNVFNILIVYILFQFIFAVIAVQLFQGKFFYCNDASKSSRETCRGYFFDY--AGRSTPETKKRLWQHHDFHFDNILYAMLTLFTVTTGEGWPTVLKNSMESTNIDNGPIADYRQEMAXXXXXXXXXXXXXXXXXXXALIIITFQEQGENELIDLDLDKNQKQCIDFAINEKPLCRYMPKDKTTIKYRVWRLVVSTPFEYFIMVMIALNTLILMMKYYREEKKASSAATHDREQQAYLNYCNTLIFLNSAFTVMFSIECVLKIMAFGPKNYFRDPWNIFDFITVIGSITDVLVSEL----------------------------------QDXXXXXXXXXXXXXXXXXXXXXXQGYTIRILLWTFIQSFKALPYVCLLIAMLFFIYSIIGMQVFGNIKLISEYQINRHNNFQTFTNGLLLLFRCATGESWQEIMLACDNNKPCEKDIENTNNF---DCGSNFTYIYFVSFIFLCSFLMLNLFVAVIMDNFDYLTRDSSILGPHHLDEYIRVWAEYDPGAIGRIHHSEMYEMLRNMEPPVGFGKKCPYRLAYRKLIRMNMPVDENGTVNFTTTLFALIRESLNIKMSTAEYMDIKDMELRQTICKMWPVQAKKKLNLIVPPDSELVFHKMTVGKIYAGYLIVENWRAYKNSQEQG 5422 L + +N IR+ I+EW PFE ++L+TI ANC+ L++ P+ D LE E FL IF VEA LK++A G H AYLRN WN++DF++VV G L D +T D++ LRA RVLRPL+LV+G PSLQVVL SII+AM PLL I LLVLF I I+AIIGLE + G H TC ++ + E+ PC+ G + QC+ WEGPN GIT+FDN +AMLTVFQCITMEGWTD++Y DA+G W+YFV L+I GSFF+LNLVLGVLSGEF+KERE+ + R F KLR +QQ E++ GY++WI +AE++ NE +DK R ++ +N+S+ ++ ET + + IR I + + R + W + FR R VKSQ FYW VI LVF NT+ +A EH+ Q +WLT + A V L LF EM++KMY L ++ YF S FN FD V+ G + E I S G+SVLR +RLLRIFK+TRYW SL NLV SLLNS+RSI SLL LLFLFI+IF+LLGMQLFGG+FNF+E + FD F ++LLTVFQILTGEDWN+VMY+GI + GG G + IYF++L + GNY LLNVFLAIAVDNLA+A+ LT+A++E+ +R A ++ + PP+ + + S+ S + ++ ++D C + N+ P +G D+ + P P + ++ K P+ A F+FS N R CH +VN F I+ I SSI+LAAEDPVK S +N IL + D+ FTG+FT+E+ILK+ G LH GS+CR+ +NILD VV +L++ G + +N +K LRVLRVLRPL+ INR LK V CV +++ + NI+IV L QF+FA I VQLF+GKFFYC D+SK ++ CRG + Y P R+W++ DF+FD++L M+ LF V+T EGWP +L +++S + D GPI +YR ++IF+I++ I+ FF +NIFV +I+TFQEQGE E + +LDKNQ+QC+++A+ +PL RY+PK+ +Y+VW +V ST FEY + +I LNT+ L M+++ + K N+ + + LN FT +F++E +LK++AF P+ YF DPWN+FDF+ VIGSI DV++SE+ ++++ +S+ F RLFR RL+KLL +G IR LLWTFI+SF+ALPYV LLI MLFFIY++IGMQ+FG I L QINR+NNFQTF +LLLFRCATGE+WQEIMLAC N+PCEK N N+ +CGS F IYFVSF LC+FL++NLFVAVIMDNFDYLTRD SILGPHHLDE+ R+WAEYDP A GRI H ++ +LR ++PP+GFGK CP+R+A ++L+ MNMP++ +GTV F TLFAL+R +L IK T ++ + ELR + K+W + K L+ +VPP + ++TVGK YA +LI E +R +K +EQG Sbjct: 143 LLCLTLKNPIRRACISIVEWKPFEIIILMTIFANCVALAVYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIAYGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKGDGATPIGGKAAGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCVHNHTG-----LNAEEKPAPCAPD---GAYGRHCTQNGTQCRVGWEGPNDGITNFDNFAFAMLTVFQCITMEGWTDVLYWMQDAMGYELPWVYFVSLVIFGSFFVLNLVLGVLSGEFSKEREKAKARGDFQKLREKQQLEEDLKGYLDWITQAEDIDPENEEEGLDDDKPRNLSMP----------ASENESVNTDNPPGGDVEGETCCTR--LAIR----ISKSKFSRYSRRW--NRLFRRKCRAAVKSQVFYWLVIFLVFLNTLTIASEHHRQPQWLTDVQDIANKVLLALFTGEMLLKMYSLGLQAYFVSLFNRFDSFVVCGGILETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDETR-RSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYGGPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEAKERKKLARLASPKKHEENE---------KPPLEEKKSEKIEL-KSITSDGETNPATKISMDD--CCGDENEEKNPYPANDYIGDDDEEEPEMPVGPRPRPLSDIHLKEKAVPMPEARAFFVFSHTNKFRVLCHKIVNHNIFTNLILFFILLSSISLAAEDPVKNDSFRNQILGYADHVFTGLFTIEIILKMTAYGAFLHKGSFCRNYFNILDLVVVSVSLIS--------------SGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKFFYCTDSSKQTQAECRGSYIMYKDGDVGKPGRSPRVWENSDFNFDDVLQGMMALFAVSTFEGWPGLLYRAIDSHSEDVGPIYNYRVVISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLRRYIPKNP--YQYKVWYVVNSTYFEYLMFTLILLNTICLAMQHHGQTK----------------NFNDAMNILNMLFTGLFTVEMILKLIAFKPRGYFSDPWNVFDFLIVIGSIIDVILSEINPADSSSSSSSSSSSSSSSTSHPPVVRPMGLQNSEENARISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQMFGKIALRDLSQINRNNNFQTFPQAVLLLFRCATGEAWQEIMLACSPNRPCEKGSTNENSTASEECGSQFAIIYFVSFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRIK--TDGNLEQANEELRAIVKKIWKRTSMKLLDQVVPPAGD---DEVTVGKFYATFLIQEYFRKFKKRKEQG 1692 HSP 2 Score: 88.9669 bits (219), Expect = 6.758e-17 Identity = 75/291 (25.77%), Postives = 134/291 (46.05%), Query Frame = 2 Query: 659 INLSFPGMQTSTSKSLFIFSEENVIRKYAKIIIEWGPFEYMVLLTILANCIVLSMERHLPKKDKTLLAGQLELTEKYFLGIFCVEALLKIVALGFCCHKEAYLRNVWNIMDFVVVVTGFLMMFLNIDNHSDSSTVD-LRTLRAVRVLRPLKLVAGFPSLQVVLKSIIRAMAPLLQIGLLVLFAITIFAIIGLEFYSGAFHYTCFKANSDKLPLPIPTEKSLVPCSNS----KNGSGLGAYTCPEDYQCKAYWEGPNYGITSFDNIGYAMLTVFQCITMEGWTDIMYHTNDA 1516 I+L + +++ F+FS N R I+ F ++L IL + I L+ E P K+ + L + F G+F +E +LK+ A G HK ++ RN +NI+D VVV + + SS ++ ++ LR +RVLRPL+ + L+ V++ + A+ + I ++ +FA IG++ + G F Y C + ++++ C S K+G P WE ++ +FD++ M+ +F T EGW ++Y D+ Sbjct: 900 IHLKEKAVPMPEARAFFVFSHTNKFRVLCHKIVNHNIFTNLILFFILLSSISLAAED--PVKNDSFRNQILGYADHVFTGLFTIEIILKMTAYGAFLHKGSFCRNYFNILDLVVVSVSLISSGIQ------SSAINVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKFFY-CTDS----------SKQTQAECRGSYIMYKDGDVGKPGRSPR------VWENSDF---NFDDVLQGMMALFAVSTFEGWPGLLYRAIDS 1162
BLAST of Voltage dependent L type calcium channel subunit vs. Ensembl Medaka
Match: cacna1c (voltage-dependent L-type calcium channel subunit alpha-1C [Source:NCBI gene;Acc:101173517]) HSP 1 Score: 1219.14 bits (3153), Expect = 0.000e+0 Identity = 744/1626 (45.76%), Postives = 1011/1626 (62.18%), Query Frame = 2 Query: 704 LFIFSEENVIRKYAKIIIEWGPFEYMVLLTILANCIVLSMERHLPKKDKTLLAGQLELTEKYFLGIFCVEALLKIVALGFCCHKEAYLRNVWNIMDFVVVVTGFLMMFLNIDNHSDSST--------VDLRTLRAVRVLRPLKLVAGFPSLQVVLKSIIRAMAPLLQIGLLVLFAITIFAIIGLEFYSGAFHYTCFKANSDKLPLPIPTEKSLVPCSNSKNGSGLGAYTCPEDYQCKAYWEGPNYGITSFDNIGYAMLTVFQCITMEGWTDIMYHTNDAIGNRFNWLYFVPLIILGSFFMLNLVLGVLSGXXXXXXXXXXXXXXXLKLRRQQQTEKEFNGYMEWIQKAEEV-LLNEATTTSEDKMRIIAARRRAEKQKYKLLGKNQSIPDFEYEDTELYSETKSMKGNIFIRSYAGIRRRRKERCTSFWRTEKHFRFSVRRLVKSQPFYWAVIILVFFNTVCVAIEHYEQGKWLTLFLNYAEYVFLCLFMMEMMIKMYGLSIRVYFQSSFNIFDCVVIAGSLFEIIYGIFVQDSSFGLSVLRALRLLRIFKVTRYWAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXGMQLFGGEFNFEEGKPPQNFDTFVKALLTVFQILTGEDWNTVMYNGIQSKGGVKERGTVFSIYFVLLVVFGNYTLLNVFLAIAVDNLANXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSSDNFIGRLPLSIDPPMVQVCPPSPQTANSLISKNFSFDHNQVEVNDKGCLLNTNK---PNGKLGMLGHDNTNFNSLESDPVPNKIEPETIQRK--PVLPYSAMFIFSPLNSLRRFCHFVVNLRYFDLFIMIVICASSIALAAEDPVKEKSLKNNILEFFDYAFTGVFTVEMILKIIDLGIILHPGSYCRDLWNILDATVVICALVAFIMGQKPSPTGNKLRGSSAKNLNTIKSLRVLRVLRPLKTINRVPKLKAVFDCVVSSLKNVFNILIVYILFQFIFAVIAVQLFQGKFFYCNDASKSSRETCRGYFFDY--AGRSTPETKKRLWQHHDFHFDNILYAMLTLFTVTTGEGWPTVLKNSMESTNIDNGPIADYRQEMAXXXXXXXXXXXXXXXXXXXALIIITFQEQGENELIDLDLDKNQKQCIDFAINEKPLCRYMPKDKTTIKYRVWRLVVSTPFEYFIMVMIALNTLILMMKYYREEKKASSAATHDREQQAYLNYCNTLIFLNSAFTVMFSIECVLKIMAFGPKNYFRDPWNIFDFITVIGSITDVLVSEL----------------------------------QDXXXXXXXXXXXXXXXXXXXXXXQGYTIRILLWTFIQSFKALPYVCLLIAMLFFIYSIIGMQVFGNIKLISEYQINRHNNFQTFTNGLLLLFRCATGESWQEIMLACDNNKPCEKDIENTNNF---DCGSNFTYIYFVSFIFLCSFLMLNLFVAVIMDNFDYLTRDSSILGPHHLDEYIRVWAEYDPGAIGRIHHSEMYEMLRNMEPPVGFGKKCPYRLAYRKLIRMNMPVDENGTVNFTTTLFALIRESLNIKMSTAEYMDIKDMELRQTICKMWPVQAKKKLNLIVPPDSELVFHKMTVGKIYAGYLIVENWRAYKNSQEQG 5422 L + +N IR+ I+EW PFE ++L+TI ANC+ L++ P+ D LE E FL IF VEA LK++A G H AYLRN WN++DF++VV G L D +T D++ LRA RVLRPL+LV+G PSLQVVL SII+AM PLL I LLVLF I I+AIIGLE + G H TC ++ + E+ PC+ G + QC+ WEGPN GIT+FDN +AMLTVFQCITMEGWTD++Y DA+G W+YFV L+I GSFF+LNLVLGVLSGEF+KERE+ + R F KLR +QQ E++ GY++WI +AE++ NE +DK R ++ +N+S+ ++ ET + + IR I + + R + W + FR R VKSQ FYW VI LVF NT+ +A EH+ Q +WLT + A V L LF EM++KMY L ++ YF S FN FD V+ G + E I S G+SVLR +RLLRIFK+TRYW SL NLV SLLNS+RSI SLL LLFLFI+IF+LLGMQLFGG+FNF+E + FD F ++LLTVFQILTGEDWN+VMY+GI + GG G + IYF++L + GNY LLNVFLAIAVDNLA+A+ LT+A++E+ +R A ++ + PP+ + + S+ S + ++ ++D C + N+ P +G D+ + P P + ++ K P+ A F+FS N R CH +VN F I+ I SSI+LAAEDPVK S +N IL + D+ FTG+FT+E+ILK+ G LH GS+CR+ +NILD VV +L++ G + +N +K LRVLRVLRPL+ INR LK V CV +++ + NI+IV L QF+FA I VQLF+GKFFYC D+SK ++ CRG + Y P R+W++ DF+FD++L M+ LF V+T EGWP +L +++S + D GPI +YR ++IF+I++ I+ FF +NIFV +I+TFQEQGE E + +LDKNQ+QC+++A+ +PL RY+PK+ +Y+VW +V ST FEY + +I LNT+ L M+++ + K N+ + + LN FT +F++E +LK++AF P+ YF DPWN+FDF+ VIGSI DV++SE+ ++++ +S+ F RLFR RL+KLL +G IR LLWTFI+SF+ALPYV LLI MLFFIY++IGMQ+FG I L QINR+NNFQTF +LLLFRCATGE+WQEIMLAC N+PCEK N N+ +CGS F IYFVSF LC+FL++NLFVAVIMDNFDYLTRD SILGPHHLDE+ R+WAEYDP A GRI H ++ +LR ++PP+GFGK CP+R+A ++L+ MNMP++ +GTV F TLFAL+R +L IK T ++ + ELR + K+W + K L+ +VPP + ++TVGK YA +LI E +R +K +EQG Sbjct: 143 LLCLTLKNPIRRACISIVEWKPFEIIILMTIFANCVALAVYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIAYGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKGDGATPIGGKAAGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCVHNHTG-----LNAEEKPAPCAPD---GAYGRHCTQNGTQCRVGWEGPNDGITNFDNFAFAMLTVFQCITMEGWTDVLYWMQDAMGYELPWVYFVSLVIFGSFFVLNLVLGVLSGEFSKEREKAKARGDFQKLREKQQLEEDLKGYLDWITQAEDIDPENEEEGLDDDKPRNLSMP----------ASENESVNTDNPPGGDVEGETCCTR--LAIR----ISKSKFSRYSRRW--NRLFRRKCRAAVKSQVFYWLVIFLVFLNTLTIASEHHRQPQWLTDVQDIANKVLLALFTGEMLLKMYSLGLQAYFVSLFNRFDSFVVCGGILETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDETR-RSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYGGPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEAKERKKLARLASPKKHEENE---------KPPLEEKKSEKIEL-KSITSDGETNPATKISMDD--CCGDENEEKNPYPANDYIGDDDEEEPEMPVGPRPRPLSDIHLKEKAVPMPEARAFFVFSHTNKFRVLCHKIVNHNIFTNLILFFILLSSISLAAEDPVKNDSFRNQILGYADHVFTGLFTIEIILKMTAYGAFLHKGSFCRNYFNILDLVVVSVSLIS--------------SGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKFFYCTDSSKQTQAECRGSYIMYKDGDVGKPGRSPRVWENSDFNFDDVLQGMMALFAVSTFEGWPGLLYRAIDSHSEDVGPIYNYRVVISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLRRYIPKNP--YQYKVWYVVNSTYFEYLMFTLILLNTICLAMQHHGQTK----------------NFNDAMNILNMLFTGLFTVEMILKLIAFKPRGYFSDPWNVFDFLIVIGSIIDVILSEINPADSSSSSSSSSSSSSSSTSHPPVVRPMGLQNSEENARISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQMFGKIALRDLSQINRNNNFQTFPQAVLLLFRCATGEAWQEIMLACSPNRPCEKGSTNENSTASEECGSQFAIIYFVSFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRIK--TDGNLEQANEELRAIVKKIWKRTSMKLLDQVVPPAGD---DEVTVGKFYATFLIQEYFRKFKKRKEQG 1692 HSP 2 Score: 88.5817 bits (218), Expect = 8.376e-17 Identity = 75/291 (25.77%), Postives = 134/291 (46.05%), Query Frame = 2 Query: 659 INLSFPGMQTSTSKSLFIFSEENVIRKYAKIIIEWGPFEYMVLLTILANCIVLSMERHLPKKDKTLLAGQLELTEKYFLGIFCVEALLKIVALGFCCHKEAYLRNVWNIMDFVVVVTGFLMMFLNIDNHSDSSTVD-LRTLRAVRVLRPLKLVAGFPSLQVVLKSIIRAMAPLLQIGLLVLFAITIFAIIGLEFYSGAFHYTCFKANSDKLPLPIPTEKSLVPCSNS----KNGSGLGAYTCPEDYQCKAYWEGPNYGITSFDNIGYAMLTVFQCITMEGWTDIMYHTNDA 1516 I+L + +++ F+FS N R I+ F ++L IL + I L+ E P K+ + L + F G+F +E +LK+ A G HK ++ RN +NI+D VVV + + SS ++ ++ LR +RVLRPL+ + L+ V++ + A+ + I ++ +FA IG++ + G F Y C + ++++ C S K+G P WE ++ +FD++ M+ +F T EGW ++Y D+ Sbjct: 900 IHLKEKAVPMPEARAFFVFSHTNKFRVLCHKIVNHNIFTNLILFFILLSSISLAAED--PVKNDSFRNQILGYADHVFTGLFTIEIILKMTAYGAFLHKGSFCRNYFNILDLVVVSVSLISSGIQ------SSAINVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKFFY-CTDS----------SKQTQAECRGSYIMYKDGDVGKPGRSPR------VWENSDF---NFDDVLQGMMALFAVSTFEGWPGLLYRAIDS 1162
BLAST of Voltage dependent L type calcium channel subunit vs. Planmine SMEST
Match: SMESG000028279.1 (SMESG000028279.1) HSP 1 Score: 4006.06 bits (10388), Expect = 0.000e+0 Identity = 2127/2142 (99.30%), Postives = 2130/2142 (99.44%), Query Frame = 2 Query: 779 MVLLTILANCIVLSMERHLPKKDKTLLAGQLELTEKYFLGIFCVEALLKIVALGFCCHKEAYLRNVWNIMDFVVVVTGFLMMFLNIDNHSDSSTVDLRTLRAVRVLRPLKLVAGFPSLQVVLKSIIRAMAPLLQIGLLVLFAITIFAIIGLEFYSGAFHYTCFKANSDKLPLPIPTEKSLVPCSNSKNGSGLGAYTCPEDYQCKAYWEGPNYGITSFDNIGYAMLTVFQCITMEGWTDIMYHTNDAIGNRFNWLYFVPLIILGSFFMLNLVLGVLSGXXXXXXXXXXXXXXXLKLRRQQQTEKEFNGYMEWIQKAEEVLLNEATTTSEDKMRIIAARRRAEKQKYKLLGKNQSIPDFEYEDTELYSETKSMKGNIFIRSYAGIRRRRKERCTSFWRTEKHFRFSVRRLVKSQPFYWAVIILVFFNTVCVAIEHYEQGKWLTLFLNYAEYVFLCLFMMEMMIKMYGLSIRVYFQSSFNIFDCVVIAGSLFEIIYGIFVQDSSFGLSVLRALRLLRIFKVTRYWAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXGMQLFGGEFNFEEGKPPQNFDTFVKALLTVFQILTGEDWNTVMYNGIQSKGGVKERGTVFSIYFVLLVVFGNYTLLNVFLAIAVDNLANXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSSDNFIGRLPLSIDPPMVQVCPPSPQTANSLISKNFSFDHNQVEVNDKGCLLNTNKPNGKLGMLGHDNTNFNSLESDPVPNKIEPETIQRKPVLPYSAMFIFSPLNSLRRFCHFVVNLRYFDLFIMIVICASSIALAAEDPVKEKSLKNNILEFFDYAFTGVFTVEMILKIIDLGIILHPGSYCRDLWNILDATVVICALVAFIMGQKPSPTGNKLRGSSAKNLNTIKSLRVLRVLRPLKTINRVPKLKAVFDCVVSSLKNVFNILIVYILFQFIFAVIAVQLFQGKFFYCNDASKSSRETCRGYFFDYAGRSTPETKKRLWQHHDFHFDNILYAMLTLFTVTTGEGWPTVLKNSMESTNIDNGPIADYRQEMAXXXXXXXXXXXXXXXXXXXALIIITFQEQGENELIDLDLDKNQKQCIDFAINEKPLCRYMPKDKTTIKYRVWRLVVSTPFEYFIMVMIALNTLILMMKYYREEKKASSAATHDREQQAYLNYCNTLIFLNSAFTVMFSIECVLKIMAFGPKNYFRDPWNIFDFITVIGSITDVLVSELQDXXXXXXXXXXXXXXXXXXXXXXQGYTIRILLWTFIQSFKALPYVCLLIAMLFFIYSIIGMQVFGNIKLISEYQINRHNNFQTFTNGLLLLFRCATGESWQEIMLACDNNKPCEKDIENTNNFDCGSNFTYIYFVSFIFLCSFLMLNLFVAVIMDNFDYLTRDSSILGPHHLDEYIRVWAEYDPGAIGRIHHSEMYEMLRNMEPPVGFGKKCPYRLAYRKLIRMNMPVDENGTVNFTTTLFALIRESLNIKMSTAEYMDIKDMELRQTICKMWPVQAKKKLNLIVPPDSELVFHKMTVGKIYAGYLIVENWRAYKNSQEQGPRSSPAVSIKSVTKPVVKEEKSANLLAKFFVAFKSNTNKSNISLDSHHERDEERFSIDHTYGEDYDANRRYSYLRRGSKPRGSKEIYSDLTPTQDYSYGLRPEHATIPGMPAPRKFGNRPRSPMYSLSELETKDRANTPQSLNSTISPTSGDRESDKFHRRSPAVSPSNPQYPFNFATAVNTIVHKANQIVEQDRRDRFYEVESEDDGIESKPNYKHQYSDDSDNKSSDTYKPSGKDRSYHVKSMTSSKYEGYINLTHSGRTTSLEVKSRSPSPVAEKKQKSNSFKEWTDLSTKYYGXXXXXXXXXXXXXINFSVCSPTIERRPNNFHREPLEESRIKYNEVYPQQKLPRIFPSPTVPKVVASDINDINFPRLNKSPTHSPTSSKFHAIPPPSADPPEDLFSSNLNDQESPPRMQTFSSYVPPLSPILYXXXXXXXXXXXXSIPLNEMEFYNDFYRTPIRNTSLQSFRDYSTYSNNFSPYFFSPQPPIHGIGQISNDNSFLLAQNDVWGMPQRSEYSGFTKTVXXXXXXXXXRTTEHSLVLSNTETSTPVNPPVSENLPLLSIRNNVSQNIRYPHERVRRNLQLXXXXXXXXWC 7204 MVLLTILANCIVLSMERHLPKKDKTLLAGQLELTEKYFLGIFCVEALLKIVALGFCCHKEAYLRNVWNIMDFVVVVTGFLMMFLNIDNHSDSSTVDLRTLRAVRVLRPLKLVAGFPSLQVVLKSIIRAMAPLLQIGLLVLFAITIFAIIGLEFYSGAFHYTCFKANSDKLPLPIPTEKSLVPCSNSKNGSGLGAYTCPEDYQCKAYWEGPNYGITSFDNIGYAMLTVFQCITMEGWTDIMYHTNDAIGNRFNWLYFVPLIILGSFFMLNLVLGVLSGEFAKERERVEKRRAFLKLRRQQQTEKEFNGYMEWIQKAEEVLLNEATTTSEDKMRIIAARRRAEKQKYKLLGKNQSIPDFEYEDTELYSETKSMKGNIFIRSYAGIRRRRKERCTSFWRTEKHFRFSVRRLVKSQPFYWAVIILVFFNTVCVAIEHYEQGKWLTLFLNYAEYVFLCLFMMEMMIKMYGLSIRVYFQSSFNIFDCVVIAGSLFEIIYG+FVQDSSFGLSVLRALRLLRIFKVTRYWASLRNLVLSLLNSMRSIISLLFLLFLFILIFALLGMQLFGGEFNFEEGKPPQNFDTFVKALLTVFQILTGEDWNTVMYNGIQSKGGVKERGTVFSIYFVLLVVFGNYTLLNVFLAIAVDNLANAQELTAAEEEKAAELQRAADAAALQNEEKSSDNFIGRLPLSIDPPMVQVCPPSPQTANSLISKNFSFDHNQVEVNDKGCLLNTNKPNGKLGMLGHDNTNFNSLESDPVPNKIEPETIQRKPVLPYSAMFIFSPLNSLRRFCHFVVNLRYFDLFIMIVICASSIALAAEDPVKEKSLKNNILEFFDYAFTGVFTVEMILKIIDLGIILHPGSYCRDLWNILDATVVICALVAFIMGQKPSPTGNKLRGSSAKNLNTIKSLRVLRVLRPLKTINRVPKLKAVFDCVVSSLKNVFNILIVYILFQFIFAVIAVQLFQGKFFYCNDASKSSRETCRGYFFDYAGRSTPETKKRLWQHHDFHFDNILYAMLTLFTVTTGEGWPTVLKNSMESTNIDNGPIADYRQEMAIFYIVFFIVFPFFFVNIFVALIIITFQEQGENELIDLDLDKNQKQCIDFAINEKPLCRYMPKDKTTIKYRVWRLVVSTPFEYFIMVMIALNTLILMMKYYREEKKASSAATHDREQQAYLNYCNTLIFLNSAFTVMFSIECVLKIMAFGPKNYFRDPWNIFDFITVIGSITDVLVSELQDSSFLSLGFLRLFRAARLIKLLRQGYTIRILLWTFIQSFKALPYVCLLIAMLFFIYSIIGMQVFGNIKLISEYQINRHNNFQTFTNGLLLLFRCATGESWQEIMLACDNNKPCEKDIENTNNFDCGSNFTYIYFVSFIFLCSFLMLNLFVAVIMDNFDYLTRDSSILGPHHLDEYIRVWAEYDPGAIGRIHHSEMYEMLRNMEPPVGFGKKCPYRLAYRKLIRMNMPVDENGTVNFTTTLFALIRESLNIKMSTAEYMDIKDMELRQTICKMWPVQAKKKLNLIVPPDSELVFHKMTVGKIYAGYLIVENWRAYKNSQEQGPRSSPAVSIKSVTKPVVKEEKSANLLAKFFVAFKSNTNKSNISLDSHHERDEERFSIDHTYGEDYDANRRYSYLRRGSKPRGSKEIYSDLTPTQDYSYGLRPEHATIPGMPAPRKFGNRPRSPMYSLSELETKDRANTPQSLNSTISPTSGDRESDKFHRRSPAVSPSNPQYPFNFATAVNTIVHKANQIVEQDRRDRFY KPNYKHQYSDDSDNKSSDTYKPSGKDRSYHVKSMTSSKYEGYINLTHSGRTTSLEVKSRSPSPVAEKKQKSN+FKEWTDLSTKYYGSSRLEERSRSPSLINFSVCSPTIERRPNNFHREPLEESRIKYNEVYPQQKLPRIFPSPTVPKVVASDINDINFPRLNKSPTHSPTSSKFHAIPPPSADPPEDLFSSNLNDQESPPRMQTFSSYVPP+SPILYDFDETDDTTFFDSIPLNEMEFYNDFYRTPIRNTSLQSFRDYSTYSNNFSPYFFSPQPPIHGIGQISNDNSFLLAQNDVWGMPQRSEYSGFTKTVSSPISISPPRTTEHSLVLSNTETSTPVNP VSENLPLLSIRNNVSQNIRYPHERVRRNLQLEEDEEDEEWC Sbjct: 1 MVLLTILANCIVLSMERHLPKKDKTLLAGQLELTEKYFLGIFCVEALLKIVALGFCCHKEAYLRNVWNIMDFVVVVTGFLMMFLNIDNHSDSSTVDLRTLRAVRVLRPLKLVAGFPSLQVVLKSIIRAMAPLLQIGLLVLFAITIFAIIGLEFYSGAFHYTCFKANSDKLPLPIPTEKSLVPCSNSKNGSGLGAYTCPEDYQCKAYWEGPNYGITSFDNIGYAMLTVFQCITMEGWTDIMYHTNDAIGNRFNWLYFVPLIILGSFFMLNLVLGVLSGEFAKERERVEKRRAFLKLRRQQQTEKEFNGYMEWIQKAEEVLLNEATTTSEDKMRIIAARRRAEKQKYKLLGKNQSIPDFEYEDTELYSETKSMKGNIFIRSYAGIRRRRKERCTSFWRTEKHFRFSVRRLVKSQPFYWAVIILVFFNTVCVAIEHYEQGKWLTLFLNYAEYVFLCLFMMEMMIKMYGLSIRVYFQSSFNIFDCVVIAGSLFEIIYGLFVQDSSFGLSVLRALRLLRIFKVTRYWASLRNLVLSLLNSMRSIISLLFLLFLFILIFALLGMQLFGGEFNFEEGKPPQNFDTFVKALLTVFQILTGEDWNTVMYNGIQSKGGVKERGTVFSIYFVLLVVFGNYTLLNVFLAIAVDNLANAQELTAAEEEKAAELQRAADAAALQNEEKSSDNFIGRLPLSIDPPMVQVCPPSPQTANSLISKNFSFDHNQVEVNDKGCLLNTNKPNGKLGMLGHDNTNFNSLESDPVPNKIEPETIQRKPVLPYSAMFIFSPLNSLRRFCHFVVNLRYFDLFIMIVICASSIALAAEDPVKEKSLKNNILEFFDYAFTGVFTVEMILKIIDLGIILHPGSYCRDLWNILDATVVICALVAFIMGQKPSPTGNKLRGSSAKNLNTIKSLRVLRVLRPLKTINRVPKLKAVFDCVVSSLKNVFNILIVYILFQFIFAVIAVQLFQGKFFYCNDASKSSRETCRGYFFDYAGRSTPETKKRLWQHHDFHFDNILYAMLTLFTVTTGEGWPTVLKNSMESTNIDNGPIADYRQEMAIFYIVFFIVFPFFFVNIFVALIIITFQEQGENELIDLDLDKNQKQCIDFAINEKPLCRYMPKDKTTIKYRVWRLVVSTPFEYFIMVMIALNTLILMMKYYREEKKASSAATHDREQQAYLNYCNTLIFLNSAFTVMFSIECVLKIMAFGPKNYFRDPWNIFDFITVIGSITDVLVSELQDSSFLSLGFLRLFRAARLIKLLRQGYTIRILLWTFIQSFKALPYVCLLIAMLFFIYSIIGMQVFGNIKLISEYQINRHNNFQTFTNGLLLLFRCATGESWQEIMLACDNNKPCEKDIENTNNFDCGSNFTYIYFVSFIFLCSFLMLNLFVAVIMDNFDYLTRDSSILGPHHLDEYIRVWAEYDPGAIGRIHHSEMYEMLRNMEPPVGFGKKCPYRLAYRKLIRMNMPVDENGTVNFTTTLFALIRESLNIKMSTAEYMDIKDMELRQTICKMWPVQAKKKLNLIVPPDSELVFHKMTVGKIYAGYLIVENWRAYKNSQEQGPRSSPAVSIKSVTKPVVKEEKSANLLAKFFVAFKSNTNKSNISLDSHHERDEERFSIDHTYGEDYDANRRYSYLRRGSKPRGSKEIYSDLTPTQDYSYGLRPEHATIPGMPAPRKFGNRPRSPMYSLSELETKDRANTPQSLNSTISPTSGDRESDKFHRRSPAVSPSNPQYPFNFATAVNTIVHKANQIVEQDRRDRFY----------GKPNYKHQYSDDSDNKSSDTYKPSGKDRSYHVKSMTSSKYEGYINLTHSGRTTSLEVKSRSPSPVAEKKQKSNAFKEWTDLSTKYYGSSRLEERSRSPSLINFSVCSPTIERRPNNFHREPLEESRIKYNEVYPQQKLPRIFPSPTVPKVVASDINDINFPRLNKSPTHSPTSSKFHAIPPPSADPPEDLFSSNLNDQESPPRMQTFSSYVPPISPILYDFDETDDTTFFDSIPLNEMEFYNDFYRTPIRNTSLQSFRDYSTYSNNFSPYFFSPQPPIHGIGQISNDNSFLLAQNDVWGMPQRSEYSGFTKTVSSPISISPPRTTEHSLVLSNTETSTPVNPSVSENLPLLSIRNNVSQNIRYPHERVRRNLQLEEDEEDEEWC 2132
BLAST of Voltage dependent L type calcium channel subunit vs. Planmine SMEST
Match: SMESG000028279.1 (SMESG000028279.1) HSP 1 Score: 3984.49 bits (10332), Expect = 0.000e+0 Identity = 2113/2128 (99.30%), Postives = 2116/2128 (99.44%), Query Frame = 2 Query: 821 MERHLPKKDKTLLAGQLELTEKYFLGIFCVEALLKIVALGFCCHKEAYLRNVWNIMDFVVVVTGFLMMFLNIDNHSDSSTVDLRTLRAVRVLRPLKLVAGFPSLQVVLKSIIRAMAPLLQIGLLVLFAITIFAIIGLEFYSGAFHYTCFKANSDKLPLPIPTEKSLVPCSNSKNGSGLGAYTCPEDYQCKAYWEGPNYGITSFDNIGYAMLTVFQCITMEGWTDIMYHTNDAIGNRFNWLYFVPLIILGSFFMLNLVLGVLSGXXXXXXXXXXXXXXXLKLRRQQQTEKEFNGYMEWIQKAEEVLLNEATTTSEDKMRIIAARRRAEKQKYKLLGKNQSIPDFEYEDTELYSETKSMKGNIFIRSYAGIRRRRKERCTSFWRTEKHFRFSVRRLVKSQPFYWAVIILVFFNTVCVAIEHYEQGKWLTLFLNYAEYVFLCLFMMEMMIKMYGLSIRVYFQSSFNIFDCVVIAGSLFEIIYGIFVQDSSFGLSVLRALRLLRIFKVTRYWAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXGMQLFGGEFNFEEGKPPQNFDTFVKALLTVFQILTGEDWNTVMYNGIQSKGGVKERGTVFSIYFVLLVVFGNYTLLNVFLAIAVDNLANXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSSDNFIGRLPLSIDPPMVQVCPPSPQTANSLISKNFSFDHNQVEVNDKGCLLNTNKPNGKLGMLGHDNTNFNSLESDPVPNKIEPETIQRKPVLPYSAMFIFSPLNSLRRFCHFVVNLRYFDLFIMIVICASSIALAAEDPVKEKSLKNNILEFFDYAFTGVFTVEMILKIIDLGIILHPGSYCRDLWNILDATVVICALVAFIMGQKPSPTGNKLRGSSAKNLNTIKSLRVLRVLRPLKTINRVPKLKAVFDCVVSSLKNVFNILIVYILFQFIFAVIAVQLFQGKFFYCNDASKSSRETCRGYFFDYAGRSTPETKKRLWQHHDFHFDNILYAMLTLFTVTTGEGWPTVLKNSMESTNIDNGPIADYRQEMAXXXXXXXXXXXXXXXXXXXALIIITFQEQGENELIDLDLDKNQKQCIDFAINEKPLCRYMPKDKTTIKYRVWRLVVSTPFEYFIMVMIALNTLILMMKYYREEKKASSAATHDREQQAYLNYCNTLIFLNSAFTVMFSIECVLKIMAFGPKNYFRDPWNIFDFITVIGSITDVLVSELQDXXXXXXXXXXXXXXXXXXXXXXQGYTIRILLWTFIQSFKALPYVCLLIAMLFFIYSIIGMQVFGNIKLISEYQINRHNNFQTFTNGLLLLFRCATGESWQEIMLACDNNKPCEKDIENTNNFDCGSNFTYIYFVSFIFLCSFLMLNLFVAVIMDNFDYLTRDSSILGPHHLDEYIRVWAEYDPGAIGRIHHSEMYEMLRNMEPPVGFGKKCPYRLAYRKLIRMNMPVDENGTVNFTTTLFALIRESLNIKMSTAEYMDIKDMELRQTICKMWPVQAKKKLNLIVPPDSELVFHKMTVGKIYAGYLIVENWRAYKNSQEQGPRSSPAVSIKSVTKPVVKEEKSANLLAKFFVAFKSNTNKSNISLDSHHERDEERFSIDHTYGEDYDANRRYSYLRRGSKPRGSKEIYSDLTPTQDYSYGLRPEHATIPGMPAPRKFGNRPRSPMYSLSELETKDRANTPQSLNSTISPTSGDRESDKFHRRSPAVSPSNPQYPFNFATAVNTIVHKANQIVEQDRRDRFYEVESEDDGIESKPNYKHQYSDDSDNKSSDTYKPSGKDRSYHVKSMTSSKYEGYINLTHSGRTTSLEVKSRSPSPVAEKKQKSNSFKEWTDLSTKYYGXXXXXXXXXXXXXINFSVCSPTIERRPNNFHREPLEESRIKYNEVYPQQKLPRIFPSPTVPKVVASDINDINFPRLNKSPTHSPTSSKFHAIPPPSADPPEDLFSSNLNDQESPPRMQTFSSYVPPLSPILYXXXXXXXXXXXXSIPLNEMEFYNDFYRTPIRNTSLQSFRDYSTYSNNFSPYFFSPQPPIHGIGQISNDNSFLLAQNDVWGMPQRSEYSGFTKTVXXXXXXXXXRTTEHSLVLSNTETSTPVNPPVSENLPLLSIRNNVSQNIRYPHERVRRNLQLXXXXXXXXWC 7204 MERHLPKKDKTLLAGQLELTEKYFLGIFCVEALLKIVALGFCCHKEAYLRNVWNIMDFVVVVTGFLMMFLNIDNHSDSSTVDLRTLRAVRVLRPLKLVAGFPSLQVVLKSIIRAMAPLLQIGLLVLFAITIFAIIGLEFYSGAFHYTCFKANSDKLPLPIPTEKSLVPCSNSKNGSGLGAYTCPEDYQCKAYWEGPNYGITSFDNIGYAMLTVFQCITMEGWTDIMYHTNDAIGNRFNWLYFVPLIILGSFFMLNLVLGVLSGEFAKERERVEKRRAFLKLRRQQQTEKEFNGYMEWIQKAEEVLLNEATTTSEDKMRIIAARRRAEKQKYKLLGKNQSIPDFEYEDTELYSETKSMKGNIFIRSYAGIRRRRKERCTSFWRTEKHFRFSVRRLVKSQPFYWAVIILVFFNTVCVAIEHYEQGKWLTLFLNYAEYVFLCLFMMEMMIKMYGLSIRVYFQSSFNIFDCVVIAGSLFEIIYG+FVQDSSFGLSVLRALRLLRIFKVTRYWASLRNLVLSLLNSMRSIISLLFLLFLFILIFALLGMQLFGGEFNFEEGKPPQNFDTFVKALLTVFQILTGEDWNTVMYNGIQSKGGVKERGTVFSIYFVLLVVFGNYTLLNVFLAIAVDNLANAQELTAAEEEKAAELQRAADAAALQNEEKSSDNFIGRLPLSIDPPMVQVCPPSPQTANSLISKNFSFDHNQVEVNDKGCLLNTNKPNGKLGMLGHDNTNFNSLESDPVPNKIEPETIQRKPVLPYSAMFIFSPLNSLRRFCHFVVNLRYFDLFIMIVICASSIALAAEDPVKEKSLKNNILEFFDYAFTGVFTVEMILKIIDLGIILHPGSYCRDLWNILDATVVICALVAFIMGQKPSPTGNKLRGSSAKNLNTIKSLRVLRVLRPLKTINRVPKLKAVFDCVVSSLKNVFNILIVYILFQFIFAVIAVQLFQGKFFYCNDASKSSRETCRGYFFDYAGRSTPETKKRLWQHHDFHFDNILYAMLTLFTVTTGEGWPTVLKNSMESTNIDNGPIADYRQEMAIFYIVFFIVFPFFFVNIFVALIIITFQEQGENELIDLDLDKNQKQCIDFAINEKPLCRYMPKDKTTIKYRVWRLVVSTPFEYFIMVMIALNTLILMMKYYREEKKASSAATHDREQQAYLNYCNTLIFLNSAFTVMFSIECVLKIMAFGPKNYFRDPWNIFDFITVIGSITDVLVSELQDSSFLSLGFLRLFRAARLIKLLRQGYTIRILLWTFIQSFKALPYVCLLIAMLFFIYSIIGMQVFGNIKLISEYQINRHNNFQTFTNGLLLLFRCATGESWQEIMLACDNNKPCEKDIENTNNFDCGSNFTYIYFVSFIFLCSFLMLNLFVAVIMDNFDYLTRDSSILGPHHLDEYIRVWAEYDPGAIGRIHHSEMYEMLRNMEPPVGFGKKCPYRLAYRKLIRMNMPVDENGTVNFTTTLFALIRESLNIKMSTAEYMDIKDMELRQTICKMWPVQAKKKLNLIVPPDSELVFHKMTVGKIYAGYLIVENWRAYKNSQEQGPRSSPAVSIKSVTKPVVKEEKSANLLAKFFVAFKSNTNKSNISLDSHHERDEERFSIDHTYGEDYDANRRYSYLRRGSKPRGSKEIYSDLTPTQDYSYGLRPEHATIPGMPAPRKFGNRPRSPMYSLSELETKDRANTPQSLNSTISPTSGDRESDKFHRRSPAVSPSNPQYPFNFATAVNTIVHKANQIVEQDRRDRFY KPNYKHQYSDDSDNKSSDTYKPSGKDRSYHVKSMTSSKYEGYINLTHSGRTTSLEVKSRSPSPVAEKKQKSN+FKEWTDLSTKYYGSSRLEERSRSPSLINFSVCSPTIERRPNNFHREPLEESRIKYNEVYPQQKLPRIFPSPTVPKVVASDINDINFPRLNKSPTHSPTSSKFHAIPPPSADPPEDLFSSNLNDQESPPRMQTFSSYVPP+SPILYDFDETDDTTFFDSIPLNEMEFYNDFYRTPIRNTSLQSFRDYSTYSNNFSPYFFSPQPPIHGIGQISNDNSFLLAQNDVWGMPQRSEYSGFTKTVSSPISISPPRTTEHSLVLSNTETSTPVNP VSENLPLLSIRNNVSQNIRYPHERVRRNLQLEEDEEDEEWC Sbjct: 1 MERHLPKKDKTLLAGQLELTEKYFLGIFCVEALLKIVALGFCCHKEAYLRNVWNIMDFVVVVTGFLMMFLNIDNHSDSSTVDLRTLRAVRVLRPLKLVAGFPSLQVVLKSIIRAMAPLLQIGLLVLFAITIFAIIGLEFYSGAFHYTCFKANSDKLPLPIPTEKSLVPCSNSKNGSGLGAYTCPEDYQCKAYWEGPNYGITSFDNIGYAMLTVFQCITMEGWTDIMYHTNDAIGNRFNWLYFVPLIILGSFFMLNLVLGVLSGEFAKERERVEKRRAFLKLRRQQQTEKEFNGYMEWIQKAEEVLLNEATTTSEDKMRIIAARRRAEKQKYKLLGKNQSIPDFEYEDTELYSETKSMKGNIFIRSYAGIRRRRKERCTSFWRTEKHFRFSVRRLVKSQPFYWAVIILVFFNTVCVAIEHYEQGKWLTLFLNYAEYVFLCLFMMEMMIKMYGLSIRVYFQSSFNIFDCVVIAGSLFEIIYGLFVQDSSFGLSVLRALRLLRIFKVTRYWASLRNLVLSLLNSMRSIISLLFLLFLFILIFALLGMQLFGGEFNFEEGKPPQNFDTFVKALLTVFQILTGEDWNTVMYNGIQSKGGVKERGTVFSIYFVLLVVFGNYTLLNVFLAIAVDNLANAQELTAAEEEKAAELQRAADAAALQNEEKSSDNFIGRLPLSIDPPMVQVCPPSPQTANSLISKNFSFDHNQVEVNDKGCLLNTNKPNGKLGMLGHDNTNFNSLESDPVPNKIEPETIQRKPVLPYSAMFIFSPLNSLRRFCHFVVNLRYFDLFIMIVICASSIALAAEDPVKEKSLKNNILEFFDYAFTGVFTVEMILKIIDLGIILHPGSYCRDLWNILDATVVICALVAFIMGQKPSPTGNKLRGSSAKNLNTIKSLRVLRVLRPLKTINRVPKLKAVFDCVVSSLKNVFNILIVYILFQFIFAVIAVQLFQGKFFYCNDASKSSRETCRGYFFDYAGRSTPETKKRLWQHHDFHFDNILYAMLTLFTVTTGEGWPTVLKNSMESTNIDNGPIADYRQEMAIFYIVFFIVFPFFFVNIFVALIIITFQEQGENELIDLDLDKNQKQCIDFAINEKPLCRYMPKDKTTIKYRVWRLVVSTPFEYFIMVMIALNTLILMMKYYREEKKASSAATHDREQQAYLNYCNTLIFLNSAFTVMFSIECVLKIMAFGPKNYFRDPWNIFDFITVIGSITDVLVSELQDSSFLSLGFLRLFRAARLIKLLRQGYTIRILLWTFIQSFKALPYVCLLIAMLFFIYSIIGMQVFGNIKLISEYQINRHNNFQTFTNGLLLLFRCATGESWQEIMLACDNNKPCEKDIENTNNFDCGSNFTYIYFVSFIFLCSFLMLNLFVAVIMDNFDYLTRDSSILGPHHLDEYIRVWAEYDPGAIGRIHHSEMYEMLRNMEPPVGFGKKCPYRLAYRKLIRMNMPVDENGTVNFTTTLFALIRESLNIKMSTAEYMDIKDMELRQTICKMWPVQAKKKLNLIVPPDSELVFHKMTVGKIYAGYLIVENWRAYKNSQEQGPRSSPAVSIKSVTKPVVKEEKSANLLAKFFVAFKSNTNKSNISLDSHHERDEERFSIDHTYGEDYDANRRYSYLRRGSKPRGSKEIYSDLTPTQDYSYGLRPEHATIPGMPAPRKFGNRPRSPMYSLSELETKDRANTPQSLNSTISPTSGDRESDKFHRRSPAVSPSNPQYPFNFATAVNTIVHKANQIVEQDRRDRFY----------GKPNYKHQYSDDSDNKSSDTYKPSGKDRSYHVKSMTSSKYEGYINLTHSGRTTSLEVKSRSPSPVAEKKQKSNAFKEWTDLSTKYYGSSRLEERSRSPSLINFSVCSPTIERRPNNFHREPLEESRIKYNEVYPQQKLPRIFPSPTVPKVVASDINDINFPRLNKSPTHSPTSSKFHAIPPPSADPPEDLFSSNLNDQESPPRMQTFSSYVPPISPILYDFDETDDTTFFDSIPLNEMEFYNDFYRTPIRNTSLQSFRDYSTYSNNFSPYFFSPQPPIHGIGQISNDNSFLLAQNDVWGMPQRSEYSGFTKTVSSPISISPPRTTEHSLVLSNTETSTPVNPSVSENLPLLSIRNNVSQNIRYPHERVRRNLQLEEDEEDEEWC 2118
BLAST of Voltage dependent L type calcium channel subunit vs. Planmine SMEST
Match: SMESG000028279.1 (SMESG000028279.1) HSP 1 Score: 3939.81 bits (10216), Expect = 0.000e+0 Identity = 2100/2149 (97.72%), Postives = 2110/2149 (98.19%), Query Frame = 2 Query: 767 PFEYMVLLTILANCIVLSMERHLPKKDKTLLAGQLELTEKYFLGIFCVEALLKIVALGFCCHKEAYLRNVWNIMDFVVVVTGFLMMFLNIDNHSDSSTVDLRTLRAVRVLRPLKLVAGFPSLQVVLKSIIRAMAPLLQIGLLVLFAITIFAIIGLEFYSGAFHYTCFKANSDKLPLPIPTEKSLVPCSNSKNGSGLGAYTCPEDYQCKAYWEGPNYGITSFDNIGYAMLTVFQCITMEGWTDIMYHTNDAIGNRFNWLYFVPLIILGSFFMLNLVLGVLSGXXXXXXXXXXXXXXXLKLRRQQQTEKEFNGYMEWIQKAEEVLLNEATTTSEDKMRIIAARRRAEKQKYKLLGKNQSIPDFEYEDTELYSETKSMKGNIFIRSYAGIRRRRKERCTSFWRTEKHFRFSVRRLVKSQPFYWAVIILVFFNTVCVAIEHYEQGKWLTLFLNYAEYVFLCLFMMEMMIKMYGLSIRVYFQSSFNIFDCVVIAGSLFEII---YGIFVQDSSFGLSVLRALRLLRIFKVTRYWAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXGMQLFGGEFNFEEGKPPQNFDTFVKALLTVFQILTGEDWNTVMYNGIQSKGGVKERGTVFSIYFVLLVVFGNYTLLNVFLAIAVDNLANXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSSDNFIGRLPLSIDPPMVQVCPPSPQTANSLISKNFSFDHNQVEVNDKGCLLNTNKPNGKLGMLGHDNTNFNSLESDPVPNKIEPETIQRKPVLPYSAMFIFSPLNSLRRFCHFVVNLRYFDLFIMIVICASSIALAAEDPVKEKSLKNNILEFFDYAFTGVFTVEMILKIIDLGIILHPGSYCRDLWNILDATVVICALVAFIMGQKPSPTGNKLRGSSAKNLNTIKSLRVLRVLRPLKTINRVPKLKAVFDCVVSSLKNVFNILIVYILFQFIFAVIAVQLFQGKFFYCNDASKSSRETCRGYFFDYAGRSTPETKKRLWQHHDFHFDNILYAMLTLFTVTTGEGWPTVLKNSMESTNIDNGPIADYRQEMAXXXXXXXXXXXXXXXXXXXALIIITFQEQGENELIDLDLDKNQKQCIDFAINEKPLCRYMPKDKTTIKYRVWRLVVSTPFEYFIMVMIALNTLILMMKYYREEKKASSAATHDREQQAYLNYCNTLIFLNSAFTVMFSIECVLKIMAFGPKNYFRDPWNIFDFITVIGSITDVLVSELQDXXXXXXXXXXXXXXXXXXXXXXQGYTIRILLWTFIQSFKALPYVCLLIAMLFFIYSIIGMQVFGNIKLISEYQINRHNNFQTFTNGLLLLFRCATGESWQEIMLACDNNKPCEKDIENTNNFDCGSNFTYIYFVSFIFLCSFLMLNLFVAVIMDNFDYLTRDSSILGPHHLDEYIRVWAEYDPGAIGRIHHSEMYEMLRNMEPPVGFGKKCPYRLAYRKLIRMNMPVDENGTVNFTTTLFALIRESLNIKMSTAEYMDIKDMELRQTICKMWPVQAKKKLNLIVPPDSELVFHKMTVGKIYAGYLIVENWRAYKNSQEQGPRSSPAVSIKSVTKPVVKEEKSANLLAKFFVAFKSNTNKSNISLDSHHERDEERFSIDHTYGEDYDANRRYSYLRRGSKPRGSKEIYSDLTPTQDYSYGLRPEHATIPGMPAPRKFGNRPRSPMYSLSELETKDRANTPQSLNSTISPTSGDRESDKFHRRSPAVSPSNPQYPFNFATAVNTIVHKANQIVEQDRRDRFYEVESEDDGIESKPNYKHQYSDDSDNKSSDTYKPSGKDRSYHVKSMTSSKYEGYINLTHSGRTTSLEVKSRSPSPVAEKKQKSNSFKEWTDLSTKYYGXXXXXXXXXXXXXINFSVCSPTIERRPNNFHREPLEESRIKYNEVYPQQKLPRIFPSPTVPKVVASDINDINFPRLNKSPTHSPTSSKFHAIPPPSADPPEDLFSSNLNDQESPPRMQTFSSYVPPLSPILYXXXXXXXXXXXXSIPLNEMEFYNDFYRTPIRNTSLQSFRDYSTYSNNFSPYFFSPQPPIHGIGQISNDNSFLLAQNDVWGMPQRSEYSGFTKTVXXXXXXXXXRTTEHSLVLSNTETSTPVNPPVSENLPLLSIRNNVSQNIRYPHERVRRNLQLXXXXXXXXWC 7204 PFEYMVLLTILANCIVLSMERHLPKKDKTLLAGQLELTEKYFLGIFCVEALLKIVALGFCCHKEAYLRNVWNIMDFVVVVTG + L + D R LRA+RVLRPLKLV GF SLQVVLKSIIRAMAPLLQIGLLVLFAITIFAIIGLEFYSGAFHYTCFKANSDKLPLPIPTEKSLVPCSNSKNGSGLGAYTCPEDYQCKAYWEGPNYGITSFDNIGYAMLTVFQCITMEGWTDIMYHTNDAIGNRFNWLYFVPLIILGSFFMLNLVLGVLSGEFAKERERVEKRRAFLKLRRQQQTEKEFNGYMEWIQKAEEVLLNEATTTSEDKMRIIAARRRAEKQKYKLLGKNQSIPDFEYEDTELYSETKSMKGNIFIRSYAGIRRRRKERCTSFWRTEKHFRFSVRRLVKSQPFYWAVIILVFFNTVCVAIEHYEQGKWLTLFLNYAEYVFLCLFMMEMMIKMYGLSIRVYFQSSFNIFDCVVIAGSLFE++ YG F+ S G +V+RALRLLRIFKVTRYWASLRNLVLSLLNSMRSIISLLFLLFLFILIFALLGMQLFGGEFNFEEGKPPQNFDTFVKALLTVFQILTGEDWNTVMYNGIQSKGGVKERGTVFSIYFVLLVVFGNYTLLNVFLAIAVDNLANAQELTAAEEEKAAELQRAADAAALQNEEKSSDNFIGRLPLSIDPPMVQVCPPSPQTANSLISKNFSFDHNQVEVNDKGCLLNTNKPNGKLGMLGHDNTNFNSLESDPVPNKIEPETIQRKPVLPYSAMFIFSPLNSLRRFCHFVVNLRYFDLFIMIVICASSIALAAEDPVKEKSLKNNILEFFDYAFTGVFTVEMILKIIDLGIILHPGSYCRDLWNILDATVVICALVAFIMGQKPSPTGNKLRGSSAKNLNTIKSLRVLRVLRPLKTINRVPKLKAVFDCVVSSLKNVFNILIVYILFQFIFAVIAVQLFQGKFFYCNDASKSSRETCRGYFFDYAGRSTPETKKRLWQHHDFHFDNILYAMLTLFTVTTGEGWPTVLKNSMESTNIDNGPIADYRQEMAIFYIVFFIVFPFFFVNIFVALIIITFQEQGENELIDLDLDKNQKQCIDFAINEKPLCRYMPKDKTTIKYRVWRLVVSTPFEYFIMVMIALNTLILMMKYYREEKKASSAATHDREQQAYLNYCNTLIFLNSAFTVMFSIECVLKIMAFGPKNYFRDPWNIFDFITVIGSITDVLVSELQDSSFLSLGFLRLFRAARLIKLLRQGYTIRILLWTFIQSFKALPYVCLLIAMLFFIYSIIGMQVFGNIKLISEYQINRHNNFQTFTNGLLLLFRCATGESWQEIMLACDNNKPCEKDIENTNNFDCGSNFTYIYFVSFIFLCSFLMLNLFVAVIMDNFDYLTRDSSILGPHHLDEYIRVWAEYDPGAIGRIHHSEMYEMLRNMEPPVGFGKKCPYRLAYRKLIRMNMPVDENGTVNFTTTLFALIRESLNIKMSTAEYMDIKDMELRQTICKMWPVQAKKKLNLIVPPDSELVFHKMTVGKIYAGYLIVENWRAYKNSQEQGPRSSPAVSIKSVTKPVVKEEKSANLLAKFFVAFKSNTNKSNISLDSHHERDEERFSIDHTYGEDYDANRRYSYLRRGSKPRGSKEIYSDLTPTQDYSYGLRPEHATIPGMPAPRKFGNRPRSPMYSLSELETKDRANTPQSLNSTISPTSGDRESDKFHRRSPAVSPSNPQYPFNFATAVNTIVHKANQIVEQDRRDRFY KPNYKHQYSDDSDNKSSDTYKPSGKDRSYHVKSMTSSKYEGYINLTHSGRTTSLEVKSRSPSPVAEKKQKSN+FKEWTDLSTKYYGSSRLEERSRSPSLINFSVCSPTIERRPNNFHREPLEESRIKYNEVYPQQKLPRIFPSPTVPKVVASDINDINFPRLNKSPTHSPTSSKFHAIPPPSADPPEDLFSSNLNDQESPPRMQTFSSYVPP+SPILYDFDETDDTTFFDSIPLNEMEFYNDFYRTPIRNTSLQSFRDYSTYSNNFSPYFFSPQPPIHGIGQISNDNSFLLAQNDVWGMPQRSEYSGFTKTVSSPISISPPRTTEHSLVLSNTETSTPVNP VSENLPLLSIRNNVSQNIRYPHERVRRNLQLEEDEEDEEWC Sbjct: 20 PFEYMVLLTILANCIVLSMERHLPKKDKTLLAGQLELTEKYFLGIFCVEALLKIVALGFCCHKEAYLRNVWNIMDFVVVVTGLISHVL--------PSFDQRALRALRVLRPLKLVTGFESLQVVLKSIIRAMAPLLQIGLLVLFAITIFAIIGLEFYSGAFHYTCFKANSDKLPLPIPTEKSLVPCSNSKNGSGLGAYTCPEDYQCKAYWEGPNYGITSFDNIGYAMLTVFQCITMEGWTDIMYHTNDAIGNRFNWLYFVPLIILGSFFMLNLVLGVLSGEFAKERERVEKRRAFLKLRRQQQTEKEFNGYMEWIQKAEEVLLNEATTTSEDKMRIIAARRRAEKQKYKLLGKNQSIPDFEYEDTELYSETKSMKGNIFIRSYAGIRRRRKERCTSFWRTEKHFRFSVRRLVKSQPFYWAVIILVFFNTVCVAIEHYEQGKWLTLFLNYAEYVFLCLFMMEMMIKMYGLSIRVYFQSSFNIFDCVVIAGSLFELLGSHYGNFM---SLGFTVMRALRLLRIFKVTRYWASLRNLVLSLLNSMRSIISLLFLLFLFILIFALLGMQLFGGEFNFEEGKPPQNFDTFVKALLTVFQILTGEDWNTVMYNGIQSKGGVKERGTVFSIYFVLLVVFGNYTLLNVFLAIAVDNLANAQELTAAEEEKAAELQRAADAAALQNEEKSSDNFIGRLPLSIDPPMVQVCPPSPQTANSLISKNFSFDHNQVEVNDKGCLLNTNKPNGKLGMLGHDNTNFNSLESDPVPNKIEPETIQRKPVLPYSAMFIFSPLNSLRRFCHFVVNLRYFDLFIMIVICASSIALAAEDPVKEKSLKNNILEFFDYAFTGVFTVEMILKIIDLGIILHPGSYCRDLWNILDATVVICALVAFIMGQKPSPTGNKLRGSSAKNLNTIKSLRVLRVLRPLKTINRVPKLKAVFDCVVSSLKNVFNILIVYILFQFIFAVIAVQLFQGKFFYCNDASKSSRETCRGYFFDYAGRSTPETKKRLWQHHDFHFDNILYAMLTLFTVTTGEGWPTVLKNSMESTNIDNGPIADYRQEMAIFYIVFFIVFPFFFVNIFVALIIITFQEQGENELIDLDLDKNQKQCIDFAINEKPLCRYMPKDKTTIKYRVWRLVVSTPFEYFIMVMIALNTLILMMKYYREEKKASSAATHDREQQAYLNYCNTLIFLNSAFTVMFSIECVLKIMAFGPKNYFRDPWNIFDFITVIGSITDVLVSELQDSSFLSLGFLRLFRAARLIKLLRQGYTIRILLWTFIQSFKALPYVCLLIAMLFFIYSIIGMQVFGNIKLISEYQINRHNNFQTFTNGLLLLFRCATGESWQEIMLACDNNKPCEKDIENTNNFDCGSNFTYIYFVSFIFLCSFLMLNLFVAVIMDNFDYLTRDSSILGPHHLDEYIRVWAEYDPGAIGRIHHSEMYEMLRNMEPPVGFGKKCPYRLAYRKLIRMNMPVDENGTVNFTTTLFALIRESLNIKMSTAEYMDIKDMELRQTICKMWPVQAKKKLNLIVPPDSELVFHKMTVGKIYAGYLIVENWRAYKNSQEQGPRSSPAVSIKSVTKPVVKEEKSANLLAKFFVAFKSNTNKSNISLDSHHERDEERFSIDHTYGEDYDANRRYSYLRRGSKPRGSKEIYSDLTPTQDYSYGLRPEHATIPGMPAPRKFGNRPRSPMYSLSELETKDRANTPQSLNSTISPTSGDRESDKFHRRSPAVSPSNPQYPFNFATAVNTIVHKANQIVEQDRRDRFY----------GKPNYKHQYSDDSDNKSSDTYKPSGKDRSYHVKSMTSSKYEGYINLTHSGRTTSLEVKSRSPSPVAEKKQKSNAFKEWTDLSTKYYGSSRLEERSRSPSLINFSVCSPTIERRPNNFHREPLEESRIKYNEVYPQQKLPRIFPSPTVPKVVASDINDINFPRLNKSPTHSPTSSKFHAIPPPSADPPEDLFSSNLNDQESPPRMQTFSSYVPPISPILYDFDETDDTTFFDSIPLNEMEFYNDFYRTPIRNTSLQSFRDYSTYSNNFSPYFFSPQPPIHGIGQISNDNSFLLAQNDVWGMPQRSEYSGFTKTVSSPISISPPRTTEHSLVLSNTETSTPVNPSVSENLPLLSIRNNVSQNIRYPHERVRRNLQLEEDEEDEEWC 2147 HSP 2 Score: 73.1738 bits (178), Expect = 3.033e-12 Identity = 74/311 (23.79%), Postives = 123/311 (39.55%), Query Frame = 2 Query: 4154 TPFEYFIMVMIALNTLILMMKYYREEKKASSAATHDREQQAYLNYCNTLIFLNSAFTVMFSIECVLKIMAFG----PKNYFRDPWNIFDFITVI-GSITDVLVSELQDXXXXXXXXXXXXXXXXXXXXXXQGY-TIRILLWTFIQSFKALPYVCLLIAMLFFIYSIIGMQVF--------------------------------------GNIKLISEYQINRH--------NNFQTFTNGLLLLFRCATGESWQEIMLACDNNKPCEKDIENTNNFDCGSNFTYIYFVSFIFLCSFLMLNLFVAVIMDNF 4930 TPFEY +++ I N ++L M+ + +K + A + Y F +F +E +LKI+A G + Y R+ WNI DF+ V+ G I+ VL S Q L G+ +++++L + I++ L + LL+ I++IIG++ + G +YQ + +F +L +F+C T E W +IM +TN+ G+ F ++YFV I L SF MLNL + V+ F Sbjct: 19 TPFEYMVLLTILANCIVLSMERHLPKKDKTLLAGQLELTEKY-------------FLGIFCVEALLKIVALGFCCHKEAYLRNVWNIMDFVVVVTGLISHVLPSFDQ--------RALRALRVLRPLKLVTGFESLQVVLKSIIRAMAPLLQIGLLVLFAITIFAIIGLEFYSGAFHYTCFKANSDKLPLPIPTEKSLVPCSNSKNGSGLGAYTCPEDYQCKAYWEGPNYGITSFDNIGYAMLTVFQCITMEGWTDIMY-------------HTND-AIGNRFNWLYFVPLIILGSFFMLNLVLGVLSGEF 294
BLAST of Voltage dependent L type calcium channel subunit vs. Planmine SMEST
Match: SMESG000028279.1 (SMESG000028279.1) HSP 1 Score: 3927.87 bits (10185), Expect = 0.000e+0 Identity = 2096/2145 (97.72%), Postives = 2106/2145 (98.18%), Query Frame = 2 Query: 779 MVLLTILANCIVLSMERHLPKKDKTLLAGQLELTEKYFLGIFCVEALLKIVALGFCCHKEAYLRNVWNIMDFVVVVTGFLMMFLNIDNHSDSSTVDLRTLRAVRVLRPLKLVAGFPSLQVVLKSIIRAMAPLLQIGLLVLFAITIFAIIGLEFYSGAFHYTCFKANSDKLPLPIPTEKSLVPCSNSKNGSGLGAYTCPEDYQCKAYWEGPNYGITSFDNIGYAMLTVFQCITMEGWTDIMYHTNDAIGNRFNWLYFVPLIILGSFFMLNLVLGVLSGXXXXXXXXXXXXXXXLKLRRQQQTEKEFNGYMEWIQKAEEVLLNEATTTSEDKMRIIAARRRAEKQKYKLLGKNQSIPDFEYEDTELYSETKSMKGNIFIRSYAGIRRRRKERCTSFWRTEKHFRFSVRRLVKSQPFYWAVIILVFFNTVCVAIEHYEQGKWLTLFLNYAEYVFLCLFMMEMMIKMYGLSIRVYFQSSFNIFDCVVIAGSLFEII---YGIFVQDSSFGLSVLRALRLLRIFKVTRYWAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXGMQLFGGEFNFEEGKPPQNFDTFVKALLTVFQILTGEDWNTVMYNGIQSKGGVKERGTVFSIYFVLLVVFGNYTLLNVFLAIAVDNLANXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSSDNFIGRLPLSIDPPMVQVCPPSPQTANSLISKNFSFDHNQVEVNDKGCLLNTNKPNGKLGMLGHDNTNFNSLESDPVPNKIEPETIQRKPVLPYSAMFIFSPLNSLRRFCHFVVNLRYFDLFIMIVICASSIALAAEDPVKEKSLKNNILEFFDYAFTGVFTVEMILKIIDLGIILHPGSYCRDLWNILDATVVICALVAFIMGQKPSPTGNKLRGSSAKNLNTIKSLRVLRVLRPLKTINRVPKLKAVFDCVVSSLKNVFNILIVYILFQFIFAVIAVQLFQGKFFYCNDASKSSRETCRGYFFDYAGRSTPETKKRLWQHHDFHFDNILYAMLTLFTVTTGEGWPTVLKNSMESTNIDNGPIADYRQEMAXXXXXXXXXXXXXXXXXXXALIIITFQEQGENELIDLDLDKNQKQCIDFAINEKPLCRYMPKDKTTIKYRVWRLVVSTPFEYFIMVMIALNTLILMMKYYREEKKASSAATHDREQQAYLNYCNTLIFLNSAFTVMFSIECVLKIMAFGPKNYFRDPWNIFDFITVIGSITDVLVSELQDXXXXXXXXXXXXXXXXXXXXXXQGYTIRILLWTFIQSFKALPYVCLLIAMLFFIYSIIGMQVFGNIKLISEYQINRHNNFQTFTNGLLLLFRCATGESWQEIMLACDNNKPCEKDIENTNNFDCGSNFTYIYFVSFIFLCSFLMLNLFVAVIMDNFDYLTRDSSILGPHHLDEYIRVWAEYDPGAIGRIHHSEMYEMLRNMEPPVGFGKKCPYRLAYRKLIRMNMPVDENGTVNFTTTLFALIRESLNIKMSTAEYMDIKDMELRQTICKMWPVQAKKKLNLIVPPDSELVFHKMTVGKIYAGYLIVENWRAYKNSQEQGPRSSPAVSIKSVTKPVVKEEKSANLLAKFFVAFKSNTNKSNISLDSHHERDEERFSIDHTYGEDYDANRRYSYLRRGSKPRGSKEIYSDLTPTQDYSYGLRPEHATIPGMPAPRKFGNRPRSPMYSLSELETKDRANTPQSLNSTISPTSGDRESDKFHRRSPAVSPSNPQYPFNFATAVNTIVHKANQIVEQDRRDRFYEVESEDDGIESKPNYKHQYSDDSDNKSSDTYKPSGKDRSYHVKSMTSSKYEGYINLTHSGRTTSLEVKSRSPSPVAEKKQKSNSFKEWTDLSTKYYGXXXXXXXXXXXXXINFSVCSPTIERRPNNFHREPLEESRIKYNEVYPQQKLPRIFPSPTVPKVVASDINDINFPRLNKSPTHSPTSSKFHAIPPPSADPPEDLFSSNLNDQESPPRMQTFSSYVPPLSPILYXXXXXXXXXXXXSIPLNEMEFYNDFYRTPIRNTSLQSFRDYSTYSNNFSPYFFSPQPPIHGIGQISNDNSFLLAQNDVWGMPQRSEYSGFTKTVXXXXXXXXXRTTEHSLVLSNTETSTPVNPPVSENLPLLSIRNNVSQNIRYPHERVRRNLQLXXXXXXXXWC 7204 MVLLTILANCIVLSMERHLPKKDKTLLAGQLELTEKYFLGIFCVEALLKIVALGFCCHKEAYLRNVWNIMDFVVVVTG + L + D R LRA+RVLRPLKLV GF SLQVVLKSIIRAMAPLLQIGLLVLFAITIFAIIGLEFYSGAFHYTCFKANSDKLPLPIPTEKSLVPCSNSKNGSGLGAYTCPEDYQCKAYWEGPNYGITSFDNIGYAMLTVFQCITMEGWTDIMYHTNDAIGNRFNWLYFVPLIILGSFFMLNLVLGVLSGEFAKERERVEKRRAFLKLRRQQQTEKEFNGYMEWIQKAEEVLLNEATTTSEDKMRIIAARRRAEKQKYKLLGKNQSIPDFEYEDTELYSETKSMKGNIFIRSYAGIRRRRKERCTSFWRTEKHFRFSVRRLVKSQPFYWAVIILVFFNTVCVAIEHYEQGKWLTLFLNYAEYVFLCLFMMEMMIKMYGLSIRVYFQSSFNIFDCVVIAGSLFE++ YG F+ S G +V+RALRLLRIFKVTRYWASLRNLVLSLLNSMRSIISLLFLLFLFILIFALLGMQLFGGEFNFEEGKPPQNFDTFVKALLTVFQILTGEDWNTVMYNGIQSKGGVKERGTVFSIYFVLLVVFGNYTLLNVFLAIAVDNLANAQELTAAEEEKAAELQRAADAAALQNEEKSSDNFIGRLPLSIDPPMVQVCPPSPQTANSLISKNFSFDHNQVEVNDKGCLLNTNKPNGKLGMLGHDNTNFNSLESDPVPNKIEPETIQRKPVLPYSAMFIFSPLNSLRRFCHFVVNLRYFDLFIMIVICASSIALAAEDPVKEKSLKNNILEFFDYAFTGVFTVEMILKIIDLGIILHPGSYCRDLWNILDATVVICALVAFIMGQKPSPTGNKLRGSSAKNLNTIKSLRVLRVLRPLKTINRVPKLKAVFDCVVSSLKNVFNILIVYILFQFIFAVIAVQLFQGKFFYCNDASKSSRETCRGYFFDYAGRSTPETKKRLWQHHDFHFDNILYAMLTLFTVTTGEGWPTVLKNSMESTNIDNGPIADYRQEMAIFYIVFFIVFPFFFVNIFVALIIITFQEQGENELIDLDLDKNQKQCIDFAINEKPLCRYMPKDKTTIKYRVWRLVVSTPFEYFIMVMIALNTLILMMKYYREEKKASSAATHDREQQAYLNYCNTLIFLNSAFTVMFSIECVLKIMAFGPKNYFRDPWNIFDFITVIGSITDVLVSELQDSSFLSLGFLRLFRAARLIKLLRQGYTIRILLWTFIQSFKALPYVCLLIAMLFFIYSIIGMQVFGNIKLISEYQINRHNNFQTFTNGLLLLFRCATGESWQEIMLACDNNKPCEKDIENTNNFDCGSNFTYIYFVSFIFLCSFLMLNLFVAVIMDNFDYLTRDSSILGPHHLDEYIRVWAEYDPGAIGRIHHSEMYEMLRNMEPPVGFGKKCPYRLAYRKLIRMNMPVDENGTVNFTTTLFALIRESLNIKMSTAEYMDIKDMELRQTICKMWPVQAKKKLNLIVPPDSELVFHKMTVGKIYAGYLIVENWRAYKNSQEQGPRSSPAVSIKSVTKPVVKEEKSANLLAKFFVAFKSNTNKSNISLDSHHERDEERFSIDHTYGEDYDANRRYSYLRRGSKPRGSKEIYSDLTPTQDYSYGLRPEHATIPGMPAPRKFGNRPRSPMYSLSELETKDRANTPQSLNSTISPTSGDRESDKFHRRSPAVSPSNPQYPFNFATAVNTIVHKANQIVEQDRRDRFY KPNYKHQYSDDSDNKSSDTYKPSGKDRSYHVKSMTSSKYEGYINLTHSGRTTSLEVKSRSPSPVAEKKQKSN+FKEWTDLSTKYYGSSRLEERSRSPSLINFSVCSPTIERRPNNFHREPLEESRIKYNEVYPQQKLPRIFPSPTVPKVVASDINDINFPRLNKSPTHSPTSSKFHAIPPPSADPPEDLFSSNLNDQESPPRMQTFSSYVPP+SPILYDFDETDDTTFFDSIPLNEMEFYNDFYRTPIRNTSLQSFRDYSTYSNNFSPYFFSPQPPIHGIGQISNDNSFLLAQNDVWGMPQRSEYSGFTKTVSSPISISPPRTTEHSLVLSNTETSTPVNP VSENLPLLSIRNNVSQNIRYPHERVRRNLQLEEDEEDEEWC Sbjct: 1 MVLLTILANCIVLSMERHLPKKDKTLLAGQLELTEKYFLGIFCVEALLKIVALGFCCHKEAYLRNVWNIMDFVVVVTGLISHVL--------PSFDQRALRALRVLRPLKLVTGFESLQVVLKSIIRAMAPLLQIGLLVLFAITIFAIIGLEFYSGAFHYTCFKANSDKLPLPIPTEKSLVPCSNSKNGSGLGAYTCPEDYQCKAYWEGPNYGITSFDNIGYAMLTVFQCITMEGWTDIMYHTNDAIGNRFNWLYFVPLIILGSFFMLNLVLGVLSGEFAKERERVEKRRAFLKLRRQQQTEKEFNGYMEWIQKAEEVLLNEATTTSEDKMRIIAARRRAEKQKYKLLGKNQSIPDFEYEDTELYSETKSMKGNIFIRSYAGIRRRRKERCTSFWRTEKHFRFSVRRLVKSQPFYWAVIILVFFNTVCVAIEHYEQGKWLTLFLNYAEYVFLCLFMMEMMIKMYGLSIRVYFQSSFNIFDCVVIAGSLFELLGSHYGNFM---SLGFTVMRALRLLRIFKVTRYWASLRNLVLSLLNSMRSIISLLFLLFLFILIFALLGMQLFGGEFNFEEGKPPQNFDTFVKALLTVFQILTGEDWNTVMYNGIQSKGGVKERGTVFSIYFVLLVVFGNYTLLNVFLAIAVDNLANAQELTAAEEEKAAELQRAADAAALQNEEKSSDNFIGRLPLSIDPPMVQVCPPSPQTANSLISKNFSFDHNQVEVNDKGCLLNTNKPNGKLGMLGHDNTNFNSLESDPVPNKIEPETIQRKPVLPYSAMFIFSPLNSLRRFCHFVVNLRYFDLFIMIVICASSIALAAEDPVKEKSLKNNILEFFDYAFTGVFTVEMILKIIDLGIILHPGSYCRDLWNILDATVVICALVAFIMGQKPSPTGNKLRGSSAKNLNTIKSLRVLRVLRPLKTINRVPKLKAVFDCVVSSLKNVFNILIVYILFQFIFAVIAVQLFQGKFFYCNDASKSSRETCRGYFFDYAGRSTPETKKRLWQHHDFHFDNILYAMLTLFTVTTGEGWPTVLKNSMESTNIDNGPIADYRQEMAIFYIVFFIVFPFFFVNIFVALIIITFQEQGENELIDLDLDKNQKQCIDFAINEKPLCRYMPKDKTTIKYRVWRLVVSTPFEYFIMVMIALNTLILMMKYYREEKKASSAATHDREQQAYLNYCNTLIFLNSAFTVMFSIECVLKIMAFGPKNYFRDPWNIFDFITVIGSITDVLVSELQDSSFLSLGFLRLFRAARLIKLLRQGYTIRILLWTFIQSFKALPYVCLLIAMLFFIYSIIGMQVFGNIKLISEYQINRHNNFQTFTNGLLLLFRCATGESWQEIMLACDNNKPCEKDIENTNNFDCGSNFTYIYFVSFIFLCSFLMLNLFVAVIMDNFDYLTRDSSILGPHHLDEYIRVWAEYDPGAIGRIHHSEMYEMLRNMEPPVGFGKKCPYRLAYRKLIRMNMPVDENGTVNFTTTLFALIRESLNIKMSTAEYMDIKDMELRQTICKMWPVQAKKKLNLIVPPDSELVFHKMTVGKIYAGYLIVENWRAYKNSQEQGPRSSPAVSIKSVTKPVVKEEKSANLLAKFFVAFKSNTNKSNISLDSHHERDEERFSIDHTYGEDYDANRRYSYLRRGSKPRGSKEIYSDLTPTQDYSYGLRPEHATIPGMPAPRKFGNRPRSPMYSLSELETKDRANTPQSLNSTISPTSGDRESDKFHRRSPAVSPSNPQYPFNFATAVNTIVHKANQIVEQDRRDRFY----------GKPNYKHQYSDDSDNKSSDTYKPSGKDRSYHVKSMTSSKYEGYINLTHSGRTTSLEVKSRSPSPVAEKKQKSNAFKEWTDLSTKYYGSSRLEERSRSPSLINFSVCSPTIERRPNNFHREPLEESRIKYNEVYPQQKLPRIFPSPTVPKVVASDINDINFPRLNKSPTHSPTSSKFHAIPPPSADPPEDLFSSNLNDQESPPRMQTFSSYVPPISPILYDFDETDDTTFFDSIPLNEMEFYNDFYRTPIRNTSLQSFRDYSTYSNNFSPYFFSPQPPIHGIGQISNDNSFLLAQNDVWGMPQRSEYSGFTKTVSSPISISPPRTTEHSLVLSNTETSTPVNPSVSENLPLLSIRNNVSQNIRYPHERVRRNLQLEEDEEDEEWC 2124
BLAST of Voltage dependent L type calcium channel subunit vs. Planmine SMEST
Match: SMESG000028279.1 (SMESG000028279.1) HSP 1 Score: 3920.55 bits (10166), Expect = 0.000e+0 Identity = 2093/2146 (97.53%), Postives = 2099/2146 (97.81%), Query Frame = 2 Query: 767 PFEYMVLLTILANCIVLSMERHLPKKDKTLLAGQLELTEKYFLGIFCVEALLKIVALGFCCHKEAYLRNVWNIMDFVVVVTGFLMMFLNIDNHSDSSTVDLRTLRAVRVLRPLKLVAGFPSLQVVLKSIIRAMAPLLQIGLLVLFAITIFAIIGLEFYSGAFHYTCFKANSDKLPLPIPTEKSLVPCSNSKNGSGLGAYTCPEDYQCKAYWEGPNYGITSFDNIGYAMLTVFQCITMEGWTDIMYHTNDAIGNRFNWLYFVPLIILGSFFMLNLVLGVLSGXXXXXXXXXXXXXXXLKLRRQQQTEKEFNGYMEWIQKAEEVLLNEATTTSEDKMRIIAARRRAEKQKYKLLGKNQSIPDFEYEDTELYSETKSMKGNIFIRSYAGIRRRRKERCTSFWRTEKHFRFSVRRLVKSQPFYWAVIILVFFNTVCVAIEHYEQGKWLTLFLNYAEYVFLCLFMMEMMIKMYGLSIRVYFQSSFNIFDCVVIAGSLFEIIYGIFVQDSSFGLSVLRALRLLRIFKVTRYWAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXGMQLFGGEFNFEEGKPPQNFDTFVKALLTVFQILTGEDWNTVMYNGIQSKGGVKERGTVFSIYFVLLVVFGNYTLLNVFLAIAVDNLANXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSSDNFIGRLPLSIDPPMVQVCPPSPQTANSLISKNFSFDHNQVEVNDKGCLLNTNKPNGKLGMLGHDNTNFNSLESDPVPNKIEPETIQRKPVLPYSAMFIFSPLNSLRRFCHFVVNLRYFDLFIMIVICASSIALAAEDPVKEKSLKNNILEFFDYAFTGVFTVEMILKIIDLGIILHPGSYCRDLWNILDATVVICALVAFIMGQKPSPTGNKLRGSSAKNLNTIKSLRVLRVLRPLKTINRVPKLKAVFDCVVSSLKNVFNILIVYILFQFIFAVIAVQLFQGKFFYCNDASKSSRETCRGYFFDYAGRSTPETKKRLWQHHDFHFDNILYAMLTLFTVTTGEGWPTVLKNSMESTNIDNGPIADYRQEMAXXXXXXXXXXXXXXXXXXXALIIITFQEQGENELIDLDLDKNQKQCIDFAINEKPLCRYMPKDKTTIKYRVWRLVVSTPFEYFIMVMIALNTLILMMKYYREEKKASSAATHDREQQAYLNYCNTLIFLNSAFTVMFSIECVLKIMAFGPKNYFRDPWNIFDFITVIGSITDVLVSELQDXXXXXXXXXXXXXXXXXXXXXXQGYTIRILLWTFIQSFKALPYVCLLIAMLFFIYSIIGMQVFGNIKLISEYQINRHNNFQTFTNGLLLLFRCATGESWQEIMLACDNNKPCEKDIENTNNFDCGSNFTYIYFVSFIFLCSFLMLNLFVAVIMDNFDYLTRDSSILGPHHLDEYIRVWAEYDPGAIGRIHHSEMYEMLRNMEPPVGFGKKCPYRLAYRKLIRMNMPVDENGTVNFTTTLFALIRESLNIKMSTAEYMDIKDMELRQTICKMWPVQAKKKLNLIVPPDSELVFHKMTVGKIYAGYLIVENWRAYKNSQEQGPRSSPAVSIKSVTKPVVKEEKSANLLAKFFVAFKSNTNKSNISLDSHHERDEERFSIDHTYGEDYDANRRYSYLRRGSKPRGSKEIYSDLTPTQDYSYGLRPEHATIPGMPAPRKFGNRPRSPMYSLSELETKDRANTPQSLNSTISPTSGDRESDKFHRRSPAVSPSNPQYPFNFATAVNTIVHKANQIVEQDRRDRFYEVESEDDGIESKPNYKHQYSDDSDNKSSDTYKPSGKDRSYHVKSMTSSKYEGYINLTHSGRTTSLEVKSRSPSPVAEKKQKSNSFKEWTDLSTKYYGXXXXXXXXXXXXXINFSVCSPTIERRPNNFHREPLEESRIKYNEVYPQQKLPRIFPSPTVPKVVASDINDINFPRLNKSPTHSPTSSKFHAIPPPSADPPEDLFSSNLNDQESPPRMQTFSSYVPPLSPILYXXXXXXXXXXXXSIPLNEMEFYNDFYRTPIRNTSLQSFRDYSTYSNNFSPYFFSPQPPIHGIGQISNDNSFLLAQNDVWGMPQRSEYSGFTKTVXXXXXXXXXRTTEHSLVLSNTETSTPVNPPVSENLPLLSIRNNVSQNIRYPHERVRRNLQLXXXXXXXXWC 7204 PFEYMVLLTILANCIVLSMERHLPKKDKTLLAGQLELTEKYFLGIFCVEALLKIVALGFCCHKEAYLRNVWNIMDFVVVVTG + L + D R LRA+RVLRPLKLV GF SLQVVLKSIIRAMAPLLQIGLLVLFAITIFAIIGLEFYSGAFHYTCFKANSDKLPLPIPTEKSLVPCSNSKNGSGLGAYTCPEDYQCKAYWEGPNYGITSFDNIGYAMLTVFQCITMEGWTDIMYHTNDAIGNRFNWLYFVPLIILGSFFMLNLVLGVLSGEFAKERERVEKRRAFLKLRRQQQTEKEFNGYMEWIQKAEEVLLNEATTTSEDKMRIIAARRRAEKQKYKLLGKNQSIPDFEYEDTELYSETKSMKGNIFIRSYAGIRRRRKERCTSFWRTEKHFRFSVRRLVKSQPFYWAVIILVFFNTVCVAIEHYEQGKWLTLFLNYAEYVFLCLFMMEMMIKMYGLSIRVYFQSSFNIFDCVVIAGSLFEIIYG+FVQDSSFGLSVLRALRLLRIFKVTRYWASLRNLVLSLLNSMRSIISLLFLLFLFILIFALLGMQLFGGEFNFEEGKPPQNFDTFVKALLTVFQILTGEDWNTVMYNGIQSKGGVKERGTVFSIYFVLLVVFGNYTLLNVFLAIAVDNLANAQELTAAEEEKAAELQRAADAAALQNEEKSSDNFIGRLPLSIDPPMVQVCPPSPQTANSLISKNFSFDHNQVEVNDKGCLLNTNKPNGKLGMLGHDNTNFNSLESDPVPNKIEPETIQRKPVLPYSAMFIFSPLNSLRRFCHFVVNLRYFDLFIMIVICASSIALAAEDPVKEKSLKNNILEFFDYAFTGVFTVEMILKIIDLGIILHPGSYCRDLWNILDATVVICALVAFIMGQKPSPTGNKLRGSSAKNLNTIKSLRVLRVLRPLKTINRVPKLKAVFDCVVSSLKNVFNILIVYILFQFIFAVIAVQLFQGKFFYCNDASKSSRETCRGYFFDYAGRSTPETKKRLWQHHDFHFDNILYAMLTLFTVTTGEGWPTVLKNSMESTNIDNGPIADYRQEMAIFYIVFFIVFPFFFVNIFVALIIITFQEQGENELIDLDLDKNQKQCIDFAINEKPLCRYMPKDKTTIKYRVWRLVVSTPFEYFIMVMIALNTLILMMKYYREEKKASSAATHDREQQAYLNYCNTLIFLNSAFTVMFSIECVLKIMAFGPKNYFRDPWNIFDFITVIGSITDVLVSELQDSSFLSLGFLRLFRAARLIKLLRQGYTIRILLWTFIQSFKALPYVCLLIAMLFFIYSIIGMQVFGNIKLISEYQINRHNNFQTFTNGLLLLFRCATGESWQEIMLACDNNKPCEKDIENTNNFDCGSNFTYIYFVSFIFLCSFLMLNLFVAVIMDNFDYLTRDSSILGPHHLDEYIRVWAEYDPGAIGRIHHSEMYEMLRNMEPPVGFGKKCPYRLAYRKLIRMNMPVDENGTVNFTTTLFALIRESLNIKMSTAEYMDIKDMELRQTICKMWPVQAKKKLNLIVPPDSELVFHKMTVGKIYAGYLIVENWRAYKNSQEQGPRS KSANLLAKFFVAFKSNTNKSNISLDSHHERDEERFSIDHTYGEDYDANRRYSYLRRGSKPRGSKEIYSDLTPTQDYSYGLRPEHATIPGMPAPRKFGNRPRSPMYSLSELETKDRANTPQSLNSTISPTSGDRESDKFHRRSPAVSPSNPQYPFNFATAVNTIVHKANQIVEQDRRDRFY KPNYKHQYSDDSDNKSSDTYKPSGKDRSYHVKSMTSSKYEGYINLTHSGRTTSLEVKSRSPSPVAEKKQKSN+FKEWTDLSTKYYGSSRLEERSRSPSLINFSVCSPTIERRPNNFHREPLEESRIKYNEVYPQQKLPRIFPSPTVPKVVASDINDINFPRLNKSPTHSPTSSKFHAIPPPSADPPEDLFSSNLNDQESPPRMQTFSSYVPP+SPILYDFDETDDTTFFDSIPLNEMEFYNDFYRTPIRNTSLQSFRDYSTYSNNFSPYFFSPQPPIHGIGQISNDNSFLLAQNDVWGMPQRSEYSGFTKTVSSPISISPPRTTEHSLVLSNTETSTPVNP VSENLPLLSIRNNVSQNIRYPHERVRRNLQLEEDEEDEEWC Sbjct: 20 PFEYMVLLTILANCIVLSMERHLPKKDKTLLAGQLELTEKYFLGIFCVEALLKIVALGFCCHKEAYLRNVWNIMDFVVVVTGLISHVL--------PSFDQRALRALRVLRPLKLVTGFESLQVVLKSIIRAMAPLLQIGLLVLFAITIFAIIGLEFYSGAFHYTCFKANSDKLPLPIPTEKSLVPCSNSKNGSGLGAYTCPEDYQCKAYWEGPNYGITSFDNIGYAMLTVFQCITMEGWTDIMYHTNDAIGNRFNWLYFVPLIILGSFFMLNLVLGVLSGEFAKERERVEKRRAFLKLRRQQQTEKEFNGYMEWIQKAEEVLLNEATTTSEDKMRIIAARRRAEKQKYKLLGKNQSIPDFEYEDTELYSETKSMKGNIFIRSYAGIRRRRKERCTSFWRTEKHFRFSVRRLVKSQPFYWAVIILVFFNTVCVAIEHYEQGKWLTLFLNYAEYVFLCLFMMEMMIKMYGLSIRVYFQSSFNIFDCVVIAGSLFEIIYGLFVQDSSFGLSVLRALRLLRIFKVTRYWASLRNLVLSLLNSMRSIISLLFLLFLFILIFALLGMQLFGGEFNFEEGKPPQNFDTFVKALLTVFQILTGEDWNTVMYNGIQSKGGVKERGTVFSIYFVLLVVFGNYTLLNVFLAIAVDNLANAQELTAAEEEKAAELQRAADAAALQNEEKSSDNFIGRLPLSIDPPMVQVCPPSPQTANSLISKNFSFDHNQVEVNDKGCLLNTNKPNGKLGMLGHDNTNFNSLESDPVPNKIEPETIQRKPVLPYSAMFIFSPLNSLRRFCHFVVNLRYFDLFIMIVICASSIALAAEDPVKEKSLKNNILEFFDYAFTGVFTVEMILKIIDLGIILHPGSYCRDLWNILDATVVICALVAFIMGQKPSPTGNKLRGSSAKNLNTIKSLRVLRVLRPLKTINRVPKLKAVFDCVVSSLKNVFNILIVYILFQFIFAVIAVQLFQGKFFYCNDASKSSRETCRGYFFDYAGRSTPETKKRLWQHHDFHFDNILYAMLTLFTVTTGEGWPTVLKNSMESTNIDNGPIADYRQEMAIFYIVFFIVFPFFFVNIFVALIIITFQEQGENELIDLDLDKNQKQCIDFAINEKPLCRYMPKDKTTIKYRVWRLVVSTPFEYFIMVMIALNTLILMMKYYREEKKASSAATHDREQQAYLNYCNTLIFLNSAFTVMFSIECVLKIMAFGPKNYFRDPWNIFDFITVIGSITDVLVSELQDSSFLSLGFLRLFRAARLIKLLRQGYTIRILLWTFIQSFKALPYVCLLIAMLFFIYSIIGMQVFGNIKLISEYQINRHNNFQTFTNGLLLLFRCATGESWQEIMLACDNNKPCEKDIENTNNFDCGSNFTYIYFVSFIFLCSFLMLNLFVAVIMDNFDYLTRDSSILGPHHLDEYIRVWAEYDPGAIGRIHHSEMYEMLRNMEPPVGFGKKCPYRLAYRKLIRMNMPVDENGTVNFTTTLFALIRESLNIKMSTAEYMDIKDMELRQTICKMWPVQAKKKLNLIVPPDSELVFHKMTVGKIYAGYLIVENWRAYKNSQEQGPRS-----------------KSANLLAKFFVAFKSNTNKSNISLDSHHERDEERFSIDHTYGEDYDANRRYSYLRRGSKPRGSKEIYSDLTPTQDYSYGLRPEHATIPGMPAPRKFGNRPRSPMYSLSELETKDRANTPQSLNSTISPTSGDRESDKFHRRSPAVSPSNPQYPFNFATAVNTIVHKANQIVEQDRRDRFY----------GKPNYKHQYSDDSDNKSSDTYKPSGKDRSYHVKSMTSSKYEGYINLTHSGRTTSLEVKSRSPSPVAEKKQKSNAFKEWTDLSTKYYGSSRLEERSRSPSLINFSVCSPTIERRPNNFHREPLEESRIKYNEVYPQQKLPRIFPSPTVPKVVASDINDINFPRLNKSPTHSPTSSKFHAIPPPSADPPEDLFSSNLNDQESPPRMQTFSSYVPPISPILYDFDETDDTTFFDSIPLNEMEFYNDFYRTPIRNTSLQSFRDYSTYSNNFSPYFFSPQPPIHGIGQISNDNSFLLAQNDVWGMPQRSEYSGFTKTVSSPISISPPRTTEHSLVLSNTETSTPVNPSVSENLPLLSIRNNVSQNIRYPHERVRRNLQLEEDEEDEEWC 2130 HSP 2 Score: 73.1738 bits (178), Expect = 3.378e-12 Identity = 74/311 (23.79%), Postives = 123/311 (39.55%), Query Frame = 2 Query: 4154 TPFEYFIMVMIALNTLILMMKYYREEKKASSAATHDREQQAYLNYCNTLIFLNSAFTVMFSIECVLKIMAFG----PKNYFRDPWNIFDFITVI-GSITDVLVSELQDXXXXXXXXXXXXXXXXXXXXXXQGY-TIRILLWTFIQSFKALPYVCLLIAMLFFIYSIIGMQVF--------------------------------------GNIKLISEYQINRH--------NNFQTFTNGLLLLFRCATGESWQEIMLACDNNKPCEKDIENTNNFDCGSNFTYIYFVSFIFLCSFLMLNLFVAVIMDNF 4930 TPFEY +++ I N ++L M+ + +K + A + Y F +F +E +LKI+A G + Y R+ WNI DF+ V+ G I+ VL S Q L G+ +++++L + I++ L + LL+ I++IIG++ + G +YQ + +F +L +F+C T E W +IM +TN+ G+ F ++YFV I L SF MLNL + V+ F Sbjct: 19 TPFEYMVLLTILANCIVLSMERHLPKKDKTLLAGQLELTEKY-------------FLGIFCVEALLKIVALGFCCHKEAYLRNVWNIMDFVVVVTGLISHVLPSFDQ--------RALRALRVLRPLKLVTGFESLQVVLKSIIRAMAPLLQIGLLVLFAITIFAIIGLEFYSGAFHYTCFKANSDKLPLPIPTEKSLVPCSNSKNGSGLGAYTCPEDYQCKAYWEGPNYGITSFDNIGYAMLTVFQCITMEGWTDIMY-------------HTND-AIGNRFNWLYFVPLIILGSFFMLNLVLGVLSGEF 294 The following BLAST results are available for this feature:
BLAST of Voltage dependent L type calcium channel subunit vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of Voltage dependent L type calcium channel subunit vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of Voltage dependent L type calcium channel subunit vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of Voltage dependent L type calcium channel subunit vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of Voltage dependent L type calcium channel subunit vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of Voltage dependent L type calcium channel subunit vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of Voltage dependent L type calcium channel subunit vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of Voltage dependent L type calcium channel subunit vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Voltage dependent L type calcium channel subunit vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of Voltage dependent L type calcium channel subunit vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 5
BLAST of Voltage dependent L type calcium channel subunit vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 1
BLAST of Voltage dependent L type calcium channel subunit vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of Voltage dependent L type calcium channel subunit vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of Voltage dependent L type calcium channel subunit vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30028403 ID=SMED30028403|Name=Voltage dependent L type calcium channel subunit|organism=Schmidtea mediterranea sexual|type=transcript|length=7253bpback to top protein sequence of SMED30028403-orf-1 >SMED30028403-orf-1 ID=SMED30028403-orf-1|Name=SMED30028403-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=2279bp MRYNEYGSTAIIKNDEKSSDQSTSSVSEENDNAVFDNGNIDGNCRYHCQRback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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