Innexin

Overview
NameInnexin
Smed IDSMED30028401
Length (bp)1485
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Innexin (SMED30028401) t-SNE clustered cells

Violin plots show distribution of expression levels for Innexin (SMED30028401) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Innexin (SMED30028401) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Innexin (SMED30028401) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30028401

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 8

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
intestinal phagocyteSMED30028401h1SMcG0001022 Contig5492GPL15192PMID:23079596
Forsthoefel et al., 2012		FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
gutSMED30028401h1SMcG0001022 AY967558smed_ncbi_20240424PMID:17670787
Oviedo et al., 2007		whole organism asexual adult colorimetric in situ hybridization evidence
Smed sexual biotypeSMED30028401h1SMcG0001022 Contig39758uc_Smed_v2PMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30028401h1SMcG0001022 Contig39758newmark_estsPMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
pharynxSMED30028401h1SMcG0001022 dd_Smed_v4_734_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
gutSMED30028401h1SMcG0001022 dd_Smed_v4_734_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30028401h1SMcG0001022 dd_Smed_v4_734_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
intestinal phagocyteSMED30028401h1SMcG0001022 dd_Smed_v6_734_0dd_Smed_v6PMID:29674432
Plass et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Innexin vs. Ensembl Celegans
Match: unc-9 (Innexin unc-9 [Source:UniProtKB/Swiss-Prot;Acc:O01393])

HSP 1 Score: 268.085 bits (684), Expect = 3.811e-85
Identity = 153/403 (37.97%), Postives = 242/403 (60.05%), Query Frame = 1 
Query:  145 SLKTRRDDDYCDRLSHHHTALFLLITSVLISSNQYVGSPIHCWVPKEFSGVWQKYANNYCWIKNTYIVPPNQKDGLIPKPSERPELEINYYQWVPIVLLCQALLFYFPSIVWRMLNWTLGINIQDLINKAMNVCTTIRPDVQKPKPNDENDASKETKVPIQEDIEPEVPQEIKDMAYHLELSIQSESNSKGSFAKTVRSLLFCGFGSRKYGFYLITLYIFTKLLYIINVVGQLFLLNSFIGTSYKLFGFQMLFNLAKGNDWKNTGHFPRITLCDFEIRNLGQRTNYTVQCVLPINLFNEKXXXXXXXXXXXVAILSVYSLFSWL-LRMIASQRFKFIQGLLEKRLKNWSTTDNNQLKRFIDEHLKTDGVFLIYLIYLNAGDLVTKELLDVMWYRYKKLSETKM 1350
            S++   DDD  D+L++++T   + + ++L+S+ QYVG PI CWVP  F+   ++Y  NYCW++NTY +P +  D +    +ER   +I YYQWVP VL  +ALLFY P+IVWR+L+W  GI++Q L+  A   C +   D++       N A +     ++E             A H++  + S +  K      + +L+ C   +R  G  +  LYI  K+LY +N+VGQ+FLLN+F+G   K +G Q+L +L  G +W+ +GHFPR+TLCDFE++ LG    +TVQCVL IN+FNEKI++F+WFW F++A  ++ SLF W+ + ++ S++  F+   L   ++ +   D+  L+RF+   L+ DGVFL+ ++  +AG+L   EL   +W  Y    E KM
Sbjct:   14 SIQFHVDDDIIDKLNYYYTTAIITVFAILVSAKQYVGFPIQCWVPATFTEPMEQYTENYCWVQNTYFLPLH--DYIPHNYAERENRQIGYYQWVPFVLALEALLFYVPTIVWRLLSWQSGIHVQSLVQMA---CDSRLLDLE-----SRNRALQTIATNVEE-------------ALHVKHQVMSGNRLK------LLNLIIC---TRSSGAAVTFLYISVKILYTVNIVGQIFLLNTFLGNRSKWYGLQVLNDLMNGREWEESGHFPRVTLCDFEVKVLGNVHRHTVQCVLMINMFNEKIFLFLWFWYFLLAGATLCSLFYWIYISVVPSRQLNFVGKYLTG-IEGYKMVDSQSLRRFVFHFLRQDGVFLLRMVATHAGELPCYELAKTLWNNYCDNKEGKM 383
[Close]
BLAST of Innexin vs. Ensembl Celegans
Match: inx-1 (Innexin [Source:UniProtKB/TrEMBL;Acc:Q17394])

HSP 1 Score: 266.929 bits (681), Expect = 7.542e-85
Identity = 148/396 (37.37%), Postives = 233/396 (58.84%), Query Frame = 1 
Query:  145 SLKTRRDDDYCDRLSHHHTALFLLITSVLISSNQYVGSPIHCWVPKEFSGVWQKYANNYCWIKNTYIVPPNQKDGLIPKPSERPELEINYYQWVPIVLLCQALLFYFPSIVWR-MLNWTLGINIQDLINKAMNVCTTIRPDVQKPKPNDENDASKETKVPIQEDIEPEVPQEIKDMAYHLELSIQSESNSKGSFAKTVRSLLFCGFGSRKYGFYLITLYIFTKLLYIINVVGQLFLLNSFIGTSYKLFGFQMLFNLAKGNDWKNTGHFPRITLCDFEIRNLGQRTNYTVQCVLPINLFNEKXXXXXXXXXXXVAILSVYSLFSW-LLRMIASQRFKFIQGLLEKRLKNWSTTDNNQLKRFIDEHLKTDGVFLIYLIYLNAGDLVTKELLDVMWYRY 1326
             L  R DDD+ D+L++H+T+  +   ++++S+ QYVG PI CWVP +F+  W++Y  NYCW++NTY +P      L  +  +R   +I+YYQWVP VL  +AL FY P I+WR +L+W  GIN+Q L   A +          +    D   A+ +T     ED   E+ +E+ D++    + +Q                       +++  Y+  LY+F K+LY+ NVV Q+F+LNSF+GT    +GF +L +L  G +W+ +G+FPR+T+CDFE+R LG   ++TVQCVL IN+FNEKI++F+WFW F+VA +S  S+F W ++  +  Q  KFI+  L         TD   +K+F+ + L  DGVF + +I  +AGD++  EL+  +W+ +
Sbjct:   12 GLHPRVDDDFVDKLNYHYTSAIIFAFAIIVSAKQYVGYPIQCWVPAQFTDAWEQYTENYCWVENTYYLPLTSAFPL--EYGDRRARQISYYQWVPFVLALEALCFYIPCIMWRGLLHWHSGINVQSLTQMACDA---------RMMDADARAATVQTIAGHMED-ALEIQREVTDVS---GMCVQ-----------------------KRWANYVTLLYVFIKMLYLGNVVLQVFMLNSFLGTDNLFYGFHILRDLLNGREWEVSGNFPRVTMCDFEVRVLGNVHHHTVQCVLMINMFNEKIFLFLWFWYFMVAFVSAVSMFHWIIISFLPGQHMKFIRKYLRATDL---ATDRQSVKKFVHKFLGYDGVFCMRMISAHAGDILATELIVALWHNF 366
[Close]
BLAST of Innexin vs. Ensembl Celegans
Match: inx-1 (Innexin [Source:UniProtKB/TrEMBL;Acc:Q17394])

HSP 1 Score: 266.929 bits (681), Expect = 7.542e-85
Identity = 148/396 (37.37%), Postives = 233/396 (58.84%), Query Frame = 1 
Query:  145 SLKTRRDDDYCDRLSHHHTALFLLITSVLISSNQYVGSPIHCWVPKEFSGVWQKYANNYCWIKNTYIVPPNQKDGLIPKPSERPELEINYYQWVPIVLLCQALLFYFPSIVWR-MLNWTLGINIQDLINKAMNVCTTIRPDVQKPKPNDENDASKETKVPIQEDIEPEVPQEIKDMAYHLELSIQSESNSKGSFAKTVRSLLFCGFGSRKYGFYLITLYIFTKLLYIINVVGQLFLLNSFIGTSYKLFGFQMLFNLAKGNDWKNTGHFPRITLCDFEIRNLGQRTNYTVQCVLPINLFNEKXXXXXXXXXXXVAILSVYSLFSW-LLRMIASQRFKFIQGLLEKRLKNWSTTDNNQLKRFIDEHLKTDGVFLIYLIYLNAGDLVTKELLDVMWYRY 1326
             L  R DDD+ D+L++H+T+  +   ++++S+ QYVG PI CWVP +F+  W++Y  NYCW++NTY +P      L  +  +R   +I+YYQWVP VL  +AL FY P I+WR +L+W  GIN+Q L   A +          +    D   A+ +T     ED   E+ +E+ D++    + +Q                       +++  Y+  LY+F K+LY+ NVV Q+F+LNSF+GT    +GF +L +L  G +W+ +G+FPR+T+CDFE+R LG   ++TVQCVL IN+FNEKI++F+WFW F+VA +S  S+F W ++  +  Q  KFI+  L         TD   +K+F+ + L  DGVF + +I  +AGD++  EL+  +W+ +
Sbjct:   12 GLHPRVDDDFVDKLNYHYTSAIIFAFAIIVSAKQYVGYPIQCWVPAQFTDAWEQYTENYCWVENTYYLPLTSAFPL--EYGDRRARQISYYQWVPFVLALEALCFYIPCIMWRGLLHWHSGINVQSLTQMACDA---------RMMDADARAATVQTIAGHMED-ALEIQREVTDVS---GMCVQ-----------------------KRWANYVTLLYVFIKMLYLGNVVLQVFMLNSFLGTDNLFYGFHILRDLLNGREWEVSGNFPRVTMCDFEVRVLGNVHHHTVQCVLMINMFNEKIFLFLWFWYFMVAFVSAVSMFHWIIISFLPGQHMKFIRKYLRATDL---ATDRQSVKKFVHKFLGYDGVFCMRMISAHAGDILATELIVALWHNF 366
[Close]
BLAST of Innexin vs. Ensembl Celegans
Match: inx-1 (Innexin [Source:UniProtKB/TrEMBL;Acc:Q17394])

HSP 1 Score: 266.159 bits (679), Expect = 5.655e-84
Identity = 151/396 (38.13%), Postives = 236/396 (59.60%), Query Frame = 1 
Query:  145 SLKTRRDDDYCDRLSHHHTALFLLITSVLISSNQYVGSPIHCWVPKEFSGVWQKYANNYCWIKNTYIVPPNQKDGLIPKPSERPELEINYYQWVPIVLLCQALLFYFPSIVWR-MLNWTLGINIQDLINKAMNVCTTIRPDVQKPKPNDENDASKETKVPIQEDIEPEVPQEIKDMAYHLELSIQSESNSKGSFAKTVRSLLFCGFGSRKYGFYLITLYIFTKLLYIINVVGQLFLLNSFIGTSYKLFGFQMLFNLAKGNDWKNTGHFPRITLCDFEIRNLGQRTNYTVQCVLPINLFNEKXXXXXXXXXXXVAILSVYSLFSW-LLRMIASQRFKFIQGLLEKRLKNWSTTDNNQLKRFIDEHLKTDGVFLIYLIYLNAGDLVTKELLDVMWYRY 1326
             L  R DDD+ D+L++H+T+  +   ++++S+ QYVG PI CWVP +F+  W++Y  NYCW++NTY +P      L  +  +R   +I+YYQWVP VL  +AL FY P I+WR +L+W  GIN+Q L   A   C     D       D   A+ +T     ED   E+ +E+ D++    + +Q                       +++  Y+  LY+F K+LY+ NVV Q+F+LNSF+GT    +GF +L +L  G +W+ +G+FPR+T+CDFE+R LG   ++TVQCVL IN+FNEKI++F+WFW F+VA +S  S+F W ++  +  Q  KFI+  L  R  + + TD   +K+F+ + L  DGVF + +I  +AGD++  EL+  +W+ +
Sbjct:   12 GLHPRVDDDFVDKLNYHYTSAIIFAFAIIVSAKQYVGYPIQCWVPAQFTDAWEQYTENYCWVENTYYLPLTSAFPL--EYGDRRARQISYYQWVPFVLALEALCFYIPCIMWRGLLHWHSGINVQSLTQMA---CDARMMDA------DARAATVQTIAGHMED-ALEIQREVTDVS---GMCVQ-----------------------KRWANYVTLLYVFIKMLYLGNVVLQVFMLNSFLGTDNLFYGFHILRDLLNGREWEVSGNFPRVTMCDFEVRVLGNVHHHTVQCVLMINMFNEKIFLFLWFWYFMVAFVSAVSMFHWIIISFLPGQHMKFIRKYL--RATDLA-TDRQSVKKFVHKFLGYDGVFCMRMISAHAGDILATELIVALWHNF 366
[Close]
BLAST of Innexin vs. Ensembl Celegans
Match: inx-13 (Innexin [Source:UniProtKB/TrEMBL;Acc:O44887])

HSP 1 Score: 259.996 bits (663), Expect = 4.100e-82
Identity = 148/407 (36.36%), Postives = 235/407 (57.74%), Query Frame = 1 
Query:  118 AFVQGLEIFSLKTRRDDDYCDRLSHHHTALFLLITSVLISSNQYVGSPIHCWVPKEFSGVWQKYANNYCWIKNTYIVPPNQKDGLIPKPS-ERPELEINYYQWVPIVLLCQALLFYFPSIVWRMLNWTLGINIQDLINKAMNVCTTIRPDVQKPKPNDENDASKETKVPIQEDIEPEVPQEIKDMAYHLELSIQSESNSKGSFAKTVRSLLFCGFGSRKYGFYLITLYIFTKLLYIINVVGQLFLLNSFIGTSYKLFGFQMLFNLAKGNDWKNTGHFPRITLCDFEIRNLGQRTNYTVQCVLPINLFNEKXXXXXXXXXXXVAILSVYSLFSWLLR-MIASQRFKFIQGLL--EKRLKNWSTTDNNQLKRFIDEHLKTDGVFLIYLIYLNAGDLVTKELLDVMWYRY 1326
            AF++GL       + DDD  DRL+++ T + L+I ++ +S+ QYVG PI CW+P +F+G W++Y+ NYC+++NTY + P   D  IP    +R   EI YYQWVP +L  QA+LFY PS+ WR++N+  G+ ++ ++  A            +      N+A+K T   + E                  L++QS       FAK   +  + G        YL  LY+F K LY++ +V Q  +LN+F+GTSY  +G  +L ++  G +W+ +GHFPR+T+CDFE+R LG +  +TVQCVL IN+FNEK+Y+F+WFW+ IV + +  +L +W  + M  S R   I+  L  E    + ++ +   L +F+D  LK+DGVF+ +LI  N G + + +++  MW R+
Sbjct:    6 AFLKGLH-----KQGDDDSIDRLNYYWTPMLLVIFALTLSAKQYVGQPIQCWIPAQFTGAWEQYSENYCFVQNTYFISP---DKYIPDSEIDREGAEIGYYQWVPFILGLQAILFYLPSLFWRLMNFNSGVALKKMLFGA--------KKADRVDEKARNEAAKSTGAHLYE-----------------SLTLQSR------FAKYTSAFTYGGS-------YLTYLYLFVKFLYLVQIVFQFIILNNFLGTSYTFWGLGILSDILNGREWEESGHFPRVTMCDFEVRVLGNKHRHTVQCVLMINMFNEKVYVFLWFWLVIVGVATFLNLVNWTRKLMFRSARKAHIKSYLQIEDNFSDDNSRNGQILDKFVDYKLKSDGVFITHLIDNNGGSVFSHDVIVDMWDRF 366
[Close]
BLAST of Innexin vs. Ensembl Fly
Match: Inx2 (gene:FBgn0027108 transcript:FBtr0301860)

HSP 1 Score: 80.1073 bits (196), Expect = 4.624e-16
Identity = 99/389 (25.45%), Postives = 167/389 (42.93%), Query Frame = 1 
Query:  181 RLSHHHTALFLLITSVLISSNQYVGSPIHCWVPKEFSGVWQKYANNYCWIKNTYIVPP-----NQKDGLIPKPSERPELEIN-----YYQWVPIVLLCQALLFYFPSIVWRMLNWTLGINIQDLINKAMNVCTTIRPDVQKPKPNDENDASKETKVPIQEDIEPEVPQEIKDMAYHLELSIQSESNSKGSFAKTVRSLLFCGFGSRKYGFYLITLYIFTKLLYIINVVGQLFLLNSFIGTSYKLFGFQML-FNLAKGNDWKN--TGHFPRITLCDFEIRN-LGQRTNYTVQCVLPINLFNEKXXXXXXXXXXXVAILSVYSLFSWLLRMIASQRFKFIQGLLEKRLKNWSTTDNNQLKRFIDEHLKTDGVFLIYLIYLNAGDLVTKELL 1305
            R+ +  T + L+  S+L++S QY+G PI C V +   GV     + YCWI +T+ VP        +D + P      E E       YYQWV  VL  QA+LFY P  +W+  +W  G  ++ L+            D+  P  NDE    +                                        K +    F G    ++ FY    ++  + L  +NV+GQ++ ++ F+   +  +G  +L F   + ++  +     FP++T C F      G    +   CVLP+N+ NEKIY+F+WFW  I++I+S  SL  + + ++A  + + +  LL  R    S    ++    +         FL+Y +  N   L+ KE++
Sbjct:   25 RMHYKATVIILIAFSLLVTSRQYIGDPIDCIVDEIPLGV----MDTYCWIYSTFTVPERLTGITGRDVVQPGVGSHVEGEDEVKYHKYYQWVCFVLFFQAILFYVPRYLWK--SWEGG-RLKMLVM-----------DLNSPIVNDECKNDR----------------------------------------KKILVDYFIG-NLNRHNFYAFRFFV-CEALNFVNVIGQIYFVDFFLDGEFSTYGSDVLKFTELEPDERIDPMARVFPKVTKCTFHKYGPSGSVQTHDGLCVLPLNIVNEKIYVFLWFWFIILSIMSGISLI-YRIAVVAGPKLRHL--LLRAR----SRLAESEEVELVANKCNIGDWFLLYQLGKNIDPLIYKEVI 346
[Close]
BLAST of Innexin vs. Ensembl Fly
Match: Inx2 (gene:FBgn0027108 transcript:FBtr0071005)

HSP 1 Score: 80.1073 bits (196), Expect = 4.624e-16
Identity = 99/389 (25.45%), Postives = 167/389 (42.93%), Query Frame = 1 
Query:  181 RLSHHHTALFLLITSVLISSNQYVGSPIHCWVPKEFSGVWQKYANNYCWIKNTYIVPP-----NQKDGLIPKPSERPELEIN-----YYQWVPIVLLCQALLFYFPSIVWRMLNWTLGINIQDLINKAMNVCTTIRPDVQKPKPNDENDASKETKVPIQEDIEPEVPQEIKDMAYHLELSIQSESNSKGSFAKTVRSLLFCGFGSRKYGFYLITLYIFTKLLYIINVVGQLFLLNSFIGTSYKLFGFQML-FNLAKGNDWKN--TGHFPRITLCDFEIRN-LGQRTNYTVQCVLPINLFNEKXXXXXXXXXXXVAILSVYSLFSWLLRMIASQRFKFIQGLLEKRLKNWSTTDNNQLKRFIDEHLKTDGVFLIYLIYLNAGDLVTKELL 1305
            R+ +  T + L+  S+L++S QY+G PI C V +   GV     + YCWI +T+ VP        +D + P      E E       YYQWV  VL  QA+LFY P  +W+  +W  G  ++ L+            D+  P  NDE    +                                        K +    F G    ++ FY    ++  + L  +NV+GQ++ ++ F+   +  +G  +L F   + ++  +     FP++T C F      G    +   CVLP+N+ NEKIY+F+WFW  I++I+S  SL  + + ++A  + + +  LL  R    S    ++    +         FL+Y +  N   L+ KE++
Sbjct:   25 RMHYKATVIILIAFSLLVTSRQYIGDPIDCIVDEIPLGV----MDTYCWIYSTFTVPERLTGITGRDVVQPGVGSHVEGEDEVKYHKYYQWVCFVLFFQAILFYVPRYLWK--SWEGG-RLKMLVM-----------DLNSPIVNDECKNDR----------------------------------------KKILVDYFIG-NLNRHNFYAFRFFV-CEALNFVNVIGQIYFVDFFLDGEFSTYGSDVLKFTELEPDERIDPMARVFPKVTKCTFHKYGPSGSVQTHDGLCVLPLNIVNEKIYVFLWFWFIILSIMSGISLI-YRIAVVAGPKLRHL--LLRAR----SRLAESEEVELVANKCNIGDWFLLYQLGKNIDPLIYKEVI 346
[Close]
BLAST of Innexin vs. Ensembl Fly
Match: Inx2 (gene:FBgn0027108 transcript:FBtr0332314)

HSP 1 Score: 80.1073 bits (196), Expect = 4.624e-16
Identity = 99/389 (25.45%), Postives = 167/389 (42.93%), Query Frame = 1 
Query:  181 RLSHHHTALFLLITSVLISSNQYVGSPIHCWVPKEFSGVWQKYANNYCWIKNTYIVPP-----NQKDGLIPKPSERPELEIN-----YYQWVPIVLLCQALLFYFPSIVWRMLNWTLGINIQDLINKAMNVCTTIRPDVQKPKPNDENDASKETKVPIQEDIEPEVPQEIKDMAYHLELSIQSESNSKGSFAKTVRSLLFCGFGSRKYGFYLITLYIFTKLLYIINVVGQLFLLNSFIGTSYKLFGFQML-FNLAKGNDWKN--TGHFPRITLCDFEIRN-LGQRTNYTVQCVLPINLFNEKXXXXXXXXXXXVAILSVYSLFSWLLRMIASQRFKFIQGLLEKRLKNWSTTDNNQLKRFIDEHLKTDGVFLIYLIYLNAGDLVTKELL 1305
            R+ +  T + L+  S+L++S QY+G PI C V +   GV     + YCWI +T+ VP        +D + P      E E       YYQWV  VL  QA+LFY P  +W+  +W  G  ++ L+            D+  P  NDE    +                                        K +    F G    ++ FY    ++  + L  +NV+GQ++ ++ F+   +  +G  +L F   + ++  +     FP++T C F      G    +   CVLP+N+ NEKIY+F+WFW  I++I+S  SL  + + ++A  + + +  LL  R    S    ++    +         FL+Y +  N   L+ KE++
Sbjct:   25 RMHYKATVIILIAFSLLVTSRQYIGDPIDCIVDEIPLGV----MDTYCWIYSTFTVPERLTGITGRDVVQPGVGSHVEGEDEVKYHKYYQWVCFVLFFQAILFYVPRYLWK--SWEGG-RLKMLVM-----------DLNSPIVNDECKNDR----------------------------------------KKILVDYFIG-NLNRHNFYAFRFFV-CEALNFVNVIGQIYFVDFFLDGEFSTYGSDVLKFTELEPDERIDPMARVFPKVTKCTFHKYGPSGSVQTHDGLCVLPLNIVNEKIYVFLWFWFIILSIMSGISLI-YRIAVVAGPKLRHL--LLRAR----SRLAESEEVELVANKCNIGDWFLLYQLGKNIDPLIYKEVI 346
[Close]
BLAST of Innexin vs. Ensembl Fly
Match: Inx2 (gene:FBgn0027108 transcript:FBtr0071006)

HSP 1 Score: 80.1073 bits (196), Expect = 4.624e-16
Identity = 99/389 (25.45%), Postives = 167/389 (42.93%), Query Frame = 1 
Query:  181 RLSHHHTALFLLITSVLISSNQYVGSPIHCWVPKEFSGVWQKYANNYCWIKNTYIVPP-----NQKDGLIPKPSERPELEIN-----YYQWVPIVLLCQALLFYFPSIVWRMLNWTLGINIQDLINKAMNVCTTIRPDVQKPKPNDENDASKETKVPIQEDIEPEVPQEIKDMAYHLELSIQSESNSKGSFAKTVRSLLFCGFGSRKYGFYLITLYIFTKLLYIINVVGQLFLLNSFIGTSYKLFGFQML-FNLAKGNDWKN--TGHFPRITLCDFEIRN-LGQRTNYTVQCVLPINLFNEKXXXXXXXXXXXVAILSVYSLFSWLLRMIASQRFKFIQGLLEKRLKNWSTTDNNQLKRFIDEHLKTDGVFLIYLIYLNAGDLVTKELL 1305
            R+ +  T + L+  S+L++S QY+G PI C V +   GV     + YCWI +T+ VP        +D + P      E E       YYQWV  VL  QA+LFY P  +W+  +W  G  ++ L+            D+  P  NDE    +                                        K +    F G    ++ FY    ++  + L  +NV+GQ++ ++ F+   +  +G  +L F   + ++  +     FP++T C F      G    +   CVLP+N+ NEKIY+F+WFW  I++I+S  SL  + + ++A  + + +  LL  R    S    ++    +         FL+Y +  N   L+ KE++
Sbjct:   25 RMHYKATVIILIAFSLLVTSRQYIGDPIDCIVDEIPLGV----MDTYCWIYSTFTVPERLTGITGRDVVQPGVGSHVEGEDEVKYHKYYQWVCFVLFFQAILFYVPRYLWK--SWEGG-RLKMLVM-----------DLNSPIVNDECKNDR----------------------------------------KKILVDYFIG-NLNRHNFYAFRFFV-CEALNFVNVIGQIYFVDFFLDGEFSTYGSDVLKFTELEPDERIDPMARVFPKVTKCTFHKYGPSGSVQTHDGLCVLPLNIVNEKIYVFLWFWFIILSIMSGISLI-YRIAVVAGPKLRHL--LLRAR----SRLAESEEVELVANKCNIGDWFLLYQLGKNIDPLIYKEVI 346
[Close]
BLAST of Innexin vs. Ensembl Fly
Match: ogre (gene:FBgn0004646 transcript:FBtr0071037)

HSP 1 Score: 70.0922 bits (170), Expect = 8.830e-13
Identity = 75/311 (24.12%), Postives = 117/311 (37.62%), Query Frame = 1 
Query:  166 DDYCDRLSHHHTALFLLITSVLISSNQYVGSPIHCWVPKEFSGVWQKYANNYCWIKNTYIVPP---NQKDGLIPKPS-------ERPELEINYYQWVPIVLLCQALLFYFPSIVWRMLNWTLGINIQDLINKAMNVCTTIRPDVQKPKPNDENDASKETKVPIQEDIEPEVPQEIKDMAYHLELSIQSESNSKGSFAKTVRSLLFCGFGSRKYGFYLITLYIFTKLLYIINVVGQLFLLNSFIGTSYKLFGFQMLFNLAKGNDWKNTGH-------FPRITLCDFEIRN-LGQRTNYTVQCVLPINLFNEK 1044
            D+   RL +  T + LL  S++I++ QYVG PI C V    +GV     N +CWI +T+ +P     Q    +  P        E  +    YYQWV  VL  QA+  Y P  +W      L      +I   +N+    R         +E +A ++  +             IK +  H   +I+                                 Y   + L  IN++ Q++L+N F    +  +G     N+ K +D             FPR+T C F      G    +   C+LP+N+ NEK
Sbjct:   20 DNAVFRLHNSFTTVLLLTCSLIITATQYVGQPISCIV----NGVPPHVVNTFCWIHSTFTMPDAFRRQVGREVAHPGVANDFGDEDAKKYYTYYQWVCFVLFFQAMACYTPKFLWNKFEGGL----MRMIVMGLNITICTR---------EEKEAKRDALLDYL----------IKHVKRHKLYAIR---------------------------------YWACEFLCCINIIVQMYLMNRFFDGEFLSYG----TNIMKLSDVPQEQRVDPMVYVFPRVTKCTFHKYGPSGSLQKHDSLCILPLNIVNEK 266
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BLAST of Innexin vs. UniProt/SwissProt
Match: sp|O01393|UNC9_CAEEL (Innexin unc-9 OS=Caenorhabditis elegans OX=6239 GN=unc-9 PE=1 SV=1)

HSP 1 Score: 268.085 bits (684), Expect = 4.848e-84
Identity = 153/403 (37.97%), Postives = 242/403 (60.05%), Query Frame = 1 
Query:  145 SLKTRRDDDYCDRLSHHHTALFLLITSVLISSNQYVGSPIHCWVPKEFSGVWQKYANNYCWIKNTYIVPPNQKDGLIPKPSERPELEINYYQWVPIVLLCQALLFYFPSIVWRMLNWTLGINIQDLINKAMNVCTTIRPDVQKPKPNDENDASKETKVPIQEDIEPEVPQEIKDMAYHLELSIQSESNSKGSFAKTVRSLLFCGFGSRKYGFYLITLYIFTKLLYIINVVGQLFLLNSFIGTSYKLFGFQMLFNLAKGNDWKNTGHFPRITLCDFEIRNLGQRTNYTVQCVLPINLFNEKXXXXXXXXXXXVAILSVYSLFSWL-LRMIASQRFKFIQGLLEKRLKNWSTTDNNQLKRFIDEHLKTDGVFLIYLIYLNAGDLVTKELLDVMWYRYKKLSETKM 1350
            S++   DDD  D+L++++T   + + ++L+S+ QYVG PI CWVP  F+   ++Y  NYCW++NTY +P +  D +    +ER   +I YYQWVP VL  +ALLFY P+IVWR+L+W  GI++Q L+  A   C +   D++       N A +     ++E             A H++  + S +  K      + +L+ C   +R  G  +  LYI  K+LY +N+VGQ+FLLN+F+G   K +G Q+L +L  G +W+ +GHFPR+TLCDFE++ LG    +TVQCVL IN+FNEKI++F+WFW F++A  ++ SLF W+ + ++ S++  F+   L   ++ +   D+  L+RF+   L+ DGVFL+ ++  +AG+L   EL   +W  Y    E KM
Sbjct:   14 SIQFHVDDDIIDKLNYYYTTAIITVFAILVSAKQYVGFPIQCWVPATFTEPMEQYTENYCWVQNTYFLPLH--DYIPHNYAERENRQIGYYQWVPFVLALEALLFYVPTIVWRLLSWQSGIHVQSLVQMA---CDSRLLDLE-----SRNRALQTIATNVEE-------------ALHVKHQVMSGNRLK------LLNLIIC---TRSSGAAVTFLYISVKILYTVNIVGQIFLLNTFLGNRSKWYGLQVLNDLMNGREWEESGHFPRVTLCDFEVKVLGNVHRHTVQCVLMINMFNEKIFLFLWFWYFLLAGATLCSLFYWIYISVVPSRQLNFVGKYLTG-IEGYKMVDSQSLRRFVFHFLRQDGVFLLRMVATHAGELPCYELAKTLWNNYCDNKEGKM 383
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BLAST of Innexin vs. UniProt/SwissProt
Match: sp|Q03412|UNC7_CAEEL (Innexin unc-7 OS=Caenorhabditis elegans OX=6239 GN=unc-7 PE=1 SV=1)

HSP 1 Score: 242.276 bits (617), Expect = 1.210e-72
Identity = 151/421 (35.87%), Postives = 231/421 (54.87%), Query Frame = 1 
Query:  100 FNTGFLAFVQGLEIFSLKTRRDDDYCDRLSHHHTALFLLITSVLISSNQYVGSPIHCWVPKEFSGVWQKYANNYCWIKNTYIVPPNQKDGLIPKP-SERPELEINYYQWVPIVLLCQALLFYFPSIVWR-MLNWTLGINIQDLINKAMNVCTTIRPDVQKPKPNDENDASKETKVPIQEDIEPEVPQEIKDMAYHLELSIQSESNSKGSFAKTVRSLLFCGFG-SRKYGFYLITLYIFTKLLYIINVVGQLFLLNSFIGTSYKLFGFQMLFNLAKGNDWKNTGHFPRITLCDFEIRNLGQRTNYTVQCVLPINLFNEKXXXXXXXXXXXVAILSVYSLFSWLLRM-IASQRFKFIQGLLEKRLKNWS--TTDNNQLKRFIDEHLKTDGVFLIYLIYLNAGDLVTKELLDVMWYRYKKLSET 1344
            F    + +       +L  R DDD+ D+L++++T   L   ++L+S+ QYVG PI CWVP  F+   ++Y  NYCW++NTY VP  Q+D  IP+    R   +I YYQWVP +L  +ALLFY P I+WR +L W  GIN+Q L+  A                 D      E K            + +  MA H++  +Q  +  +   +++  S L  G    R  G Y+  LYI  K+LY  NV+ Q FLLN  +G++   +GF +L +L    +W+ TG FPR+TLCDFE+R LG    +TVQCVL IN+FNEKI++F+WFW     I++V +   W+L M I SQ   F++  L     + +    D+  L++F +  L+ DGVF++ +I  +AG+L++ EL+  +W  +  +  +
Sbjct:  117 FGPAMILYYLASAFRALYPRLDDDFVDKLNYYYTTTILASFALLVSAKQYVGFPIQCWVPATFTDAMEQYTENYCWVQNTYWVP-MQED--IPREIYSRRNRQIGYYQWVPFILAIEALLFYVPCILWRGLLYWHSGINLQGLVQMAC----------------DARLMDSEIKT-----------RTVYTMARHMQDEVQLTNIDRQGHSRSCFSNLQLGANCGRHCGCYVTMLYIGIKVLYSANVLLQFFLLNHLLGSNDLAYGFSLLKDLMHAIEWEQTGMFPRVTLCDFEVRVLGNIHRHTVQCVLMINMFNEKIFLFLWFWFLTCGIVTVCNTMYWILIMFIPSQGMSFVRKYLRVLPDHPAKPIADDVTLRKFTNNFLRKDGVFMLRMISTHAGELMSSELILALWQDFNNVDRS 507
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BLAST of Innexin vs. UniProt/SwissProt
Match: sp|A8WVX4|INX19_CAEBR (Innexin-19 OS=Caenorhabditis briggsae OX=6238 GN=inx-19 PE=3 SV=3)

HSP 1 Score: 223.016 bits (567), Expect = 3.359e-66
Identity = 137/419 (32.70%), Postives = 223/419 (53.22%), Query Frame = 1 
Query:  139 IFSLKTRRDDDYCDRLSHHHTALFLLITSVLISSNQYVGSPIHCWVPKEFSGVWQKYANNYCWIKNTYIVPPNQKDGLIPKPSERPELEINYYQWVPIVLLCQALLFYFPSIVWRMLNWTLGINIQDLINKAMNVCTTIRPDVQKPKPNDENDASKETKVPIQEDIEPEVPQEIKDMAYHLELSIQSESNSKGSFAKTVRSLLFCGFGSRKYGFYLITLYIFTKLLYIINVVGQLFLLNSFIGTS-YKLFGFQMLFNLAKGNDWKNTGHFPRITLCDFEIRNLGQRTNYTVQCVLPINLFNEKXXXXXXXXXXXVAILSVYSLFSWLL-RMIASQRFKFIQGLLE-------KRLKNWSTTDNNQ------------LKRFIDEHLKTDGVFLIYLIYLNAGDLVTKELLDVMWYRYKK 1332
            I +L  R DDD  DRL++++T L L +  ++IS+ QY G+PI CWV        ++Y  +YCWI+NTY +P    + +    + R E +I YYQWVP +L+ +AL+F  P I WR+ ++  G+NIQ LIN A +    +         +D   A +       ++++ + P                   ++G  A+    + F  F S   G  +  +Y FTKLLY +NVV Q F+LN+ + +S +  FGFQ+L ++  G  W  TGHFPR+TLCDFE+R L     YTVQC L IN+ NEK++ F+W W  I+AI++  S   W+    I S++  ++   ++       K+L+ +      +            L  F+ + LK+DG+ ++ +I  +AGD++  +L+  +W  Y++
Sbjct:   12 ISALSVRGDDDAVDRLNYYYTPLILAVCCLVISAKQYGGTPIECWVNPHSRESMEEYIESYCWIQNTYWIP--MYENVPDDHTAREEKQIGYYQWVPFILIAEALMFSLPCIFWRLCSFQSGLNIQTLINAACDAQALL-------DYSDRQKAVEAITCNFVDNLDLQSPN--------------GRIRARGWIAR----IKFSRFLS---GQCISIVYSFTKLLYSVNVVAQFFILNACLKSSEFVFFGFQVLSDIWAGRPWTETGHFPRVTLCDFEVRYLANLNRYTVQCALLINIINEKVFAFLWCWYMILAIITTCSFIYWIANSFIHSEKVDYVMKFIQIAESSEYKKLQKFEKDATVERLYTVIAFAPHLLDSFVSDFLKSDGILMLRMISNHAGDMIVVQLVRNLWQEYRE 400
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BLAST of Innexin vs. UniProt/SwissProt
Match: sp|Q23157|INX11_CAEEL (Innexin-11 OS=Caenorhabditis elegans OX=6239 GN=inx-11 PE=3 SV=1)

HSP 1 Score: 219.935 bits (559), Expect = 1.052e-64
Identity = 134/403 (33.25%), Postives = 224/403 (55.58%), Query Frame = 1 
Query:  148 LKTRRDDDYCDRLSHHHTALFLLITSVLISSNQYVGSPIHCWVPKEFSGVWQKYANNYCWIKNTYIVPPNQKDGLIPKPSE-RPELEINYYQWVPIVLLCQALLFYFPSIVWRMLNWTLGINIQDLINKAMNVCTTIRPDVQKPKPNDENDASKETKVPIQEDIEPEVPQE-IKDMAYHLELSIQSESNSKGSFAKTVRSLLFCGFGSRKYGFYLIT-LYIFTKLLYIINVVGQLFLLNSFIGTS-YKLFGFQMLFNLAKGNDWKNTGHFPRITLCDFEIRNLGQRTNYTVQCVLPINLFNEKXXXXXXXXXXXVAILSVYSLFSWLLRMIASQRFKFI--QGLLEKRLKNW----STTDNNQLKRFIDEHLKTDGVFLIYLIYLNAGDLVTKELLDVMWYRY 1326
            L  R DDD+ DRL++  T   LL  SVLIS  Q+ G PI C  P +F G W++YA NYCW ++TY V P Q   L+ K     P+ +++YYQWVP  LL QA  F  PS +W+  +   GI I +++ KA +                              ++E EV ++ I  +  HL  +++ ++N +    +  +++ F  F   +Y    I+ +Y+FTK+LY +NV  QL+L+N F+GT+ +  +GF ++ ++ +G  W+ +G+FPR  +CDFE+R +     Y+VQCVL IN+FNEKI++ +WFW  I+ + S  SL  W + ++     K+   Q L    L+N+    S  +++ + +F+ ++L  DGVF++ ++  +AG +   +L+  ++  Y
Sbjct:   14 LSPREDDDWSDRLNYLMTPNILLAFSVLISFKQFGGRPIECMFPNKFPGSWEQYAENYCWSQDTYFVEPTQDVSLLKKEERYTPDRQLSYYQWVPFFLLLQAAFFRAPSYLWKYFSNHSGIRIHEVVEKAKDSA----------------------------NVEEEVREKNILILKRHLSSALRFQANMERKKVQVHKTVTFLNF---QYSSGFISWIYLFTKVLYFLNVFAQLYLMNYFLGTNRHHWYGFGVVQDIVQGEPWERSGYFPRAAVCDFEVRQVANIQRYSVQCVLVINIFNEKIFVLLWFWYVILLLSSTVSLVQWFIVLVFPCFSKWFVKQHLALSTLQNFNQRNSRREDSDVSKFVTQYLHKDGVFVLRMVSSHAGIIFATDLVQALYEAY 385
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BLAST of Innexin vs. UniProt/SwissProt
Match: sp|O61715|INX19_CAEEL (Innexin-19 OS=Caenorhabditis elegans OX=6239 GN=inx-19 PE=1 SV=2)

HSP 1 Score: 218.779 bits (556), Expect = 2.351e-64
Identity = 139/419 (33.17%), Postives = 221/419 (52.74%), Query Frame = 1 
Query:  139 IFSLKTRRDDDYCDRLSHHHTALFLLITSVLISSNQYVGSPIHCWVPKEFSGVWQKYANNYCWIKNTYIVPPNQKDGLIPKPSERPELEINYYQWVPIVLLCQALLFYFPSIVWRMLNWTLGINIQDLINKAMNVCTTIRPDVQKPKPNDENDASKETKVPIQEDIEPEVPQEIKDMAYHLELSIQSESNSKGSFAKTVRSLLFCGFGSRKYGFYLITLYIFTKLLYIINVVGQLFLLNSFIGTS-YKLFGFQMLFNLAKGNDWKNTGHFPRITLCDFEIRNLGQRTNYTVQCVLPINLFNEKXXXXXXXXXXXVAILSVYSLFSWL----------------LRMIASQRFKFIQGLLE----KRLKNWSTTDNNQLKRFIDEHLKTDGVFLIYLIYLNAGDLVTKELLDVMWYRYKK 1332
            I +L  R DDD  DRL++++T L L +  ++IS+ QY G+PI CWV        ++Y  +YCWI+NTY +P    + +    + R E +I YYQWVP +L+ +AL+F  P I WR+ ++  G+NIQ LIN A +    +         +D   A +       ++++ + P                   ++G  A+    + F  F S   G  L  L+ FTKLLY +NVV Q  +LN+ + +S +  FGFQ+L ++  G  W  TGHFPR+TLCDFE+R L     YTVQC L IN+ NEK++ F+W W  I+AI++  S   W+                +++  S  FK +Q   +    +RL        + L  F+ + LK+DGV ++ +I  +AGD++  +L+  +W  +++
Sbjct:   28 INALSVRGDDDAVDRLNYYYTPLILAVCCLVISAKQYGGTPIECWVNPHSRESMEEYIESYCWIQNTYWIP--MYENVPDDHTAREEKQIGYYQWVPFILIAEALMFSLPCIFWRLCSFQSGLNIQTLINAACDGQALL-------DASDRQKAVEAITTNFVDNLDLQSPN--------------GRIRARGWIAR----IKFSRFLS---GQCLSILHSFTKLLYSMNVVAQFLILNACLKSSDFLFFGFQVLNDIWAGRPWTETGHFPRVTLCDFEVRYLANLNRYTVQCALLINIINEKVFAFLWCWYMILAIITTCSFIYWIANSFIHSEKVDYVMKFIQIAESSEFKKLQKFEKDATVERLYTVIAFAPHLLDTFVSDFLKSDGVLMLRMISNHAGDMIVVQLVRNLWQEFRE 416
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BLAST of Innexin vs. TrEMBL
Match: Q9NCL5 (Innexin OS=Girardia tigrina OX=6162 GN=Panx1 PE=2 SV=1)

HSP 1 Score: 544.273 bits (1401), Expect = 0.000e+0
Identity = 272/421 (64.61%), Postives = 343/421 (81.47%), Query Frame = 1 
Query:   94 MVFNTGFLAFVQGLEIFSLKTRRDDDYCDRLSHHHTALFLLITSVLISSNQYVGSPIHCWVPKEFSGVWQKYANNYCWIKNTYIVPPNQKDGLIPKPSERPELEINYYQWVPIVLLCQALLFYFPSIVWRMLNWTLGINIQDLINKAMNVCTTIRPDVQKPKPNDENDASKETKVPIQEDIEPEVPQEIKDMAYHLELSIQSESNSKGSFAKTVRSLLFCGFGSRKYGFYLITLYIFTKLLYIINVVGQLFLLNSFIGTSYKLFGFQMLFNLAKGNDWKNTGHFPRITLCDFEIRNLGQRTNYTVQCVLPINLFNEKXXXXXXXXXXXVAILSVYSLFSWLLRMIASQRFKFIQGLLEKRLKNWSTTDNNQLKRFIDEHLKTDGVFLIYLIYLNAGDLVTKELLDVMWYRYKKLSETKMSL 1356
            MVFNTG LAFVQGL++FSL+TRRDDD+ DRLSHH+TALFLLITS+LISS QYVG PIHCWVPKEFS  WQKYANNYCWIKNTY VP       IPKP ER +LEINYYQWVPIVLL Q+LLFYFP+I+WR+LNWT+GINIQD+I KAM+VC+TIR   +K K +      ++ +    ++ EPEVP  I+D+A HLE+SI+    SK +F K +R+L  CGFGSRKYG YLITLY  TKLLYIINV+GQ+FLL   +    + FGF++L +L KG+DWK+TGHFPR+T+CDF+IRNLGQRTNY+VQCVLPINLFN+KIYIFIWFWIF+V+IL+VYS F W+ RM++ Q+ KFI+GLL K L  WS  DN+ L+ FI+++LK+DGVFL+YLIY+N+GD+VT +LL+V+W+R+K+ ++  + +
Sbjct:    1 MVFNTGLLAFVQGLKLFSLRTRRDDDFTDRLSHHYTALFLLITSILISSKQYVGDPIHCWVPKEFSDPWQKYANNYCWIKNTYTVPSYDFMS-IPKPDERKKLEINYYQWVPIVLLIQSLLFYFPTIIWRILNWTVGINIQDMIGKAMDVCSTIRTVPEKEKNDKTESKDEKEEQSSSKEEEPEVPGIIRDIANHLEISIEFVEKSKSNFVKALRNLFVCGFGSRKYGSYLITLYFVTKLLYIINVIGQIFLLTHSLNVLVRFFGFKVLSDLGKGDDWKSTGHFPRVTMCDFQIRNLGQRTNYSVQCVLPINLFNKKIYIFIWFWIFLVSILTVYSFFHWIFRMLSFQKVKFIRGLLLKGLNKWSGGDNDLLRSFINDYLKSDGVFLMYLIYINSGDIVTTQLLEVLWFRFKQKNKDSLKI 420
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BLAST of Innexin vs. TrEMBL
Match: Q2L6M2 (Innexin OS=Dugesia japonica OX=6161 GN=inx1 PE=2 SV=1)

HSP 1 Score: 380.178 bits (975), Expect = 1.372e-127
Identity = 178/242 (73.55%), Postives = 204/242 (84.30%), Query Frame = 1 
Query:   94 MVFNTGFLAFVQGLEIFSLKTRRDDDYCDRLSHHHTALFLLITSVLISSNQYVGSPIHCWVPKEFSGVWQKYANNYCWIKNTYIVPPNQKDGLIPKPSERPELEINYYQWVPIVLLCQALLFYFPSIVWRMLNWTLGINIQDLINKAMNVCTTIRPDVQKPKPNDENDASKETKVPIQEDIEPEVPQEIKDMAYHLELSIQSESNSKGSFAKTVRSLLFCGFGSRKYGFYLITLYIFTKLLY 819
            MVFNT FLAF+QGL+IFSLKTRRDDDYCDRLSHHHTA+FLLITS+LISSNQYVG+PIHCWVPKEFS  WQKYANNYCWIKNTY++PPN + G IPK  ER ELEINYYQWVPIVLLCQ+LLFY PSI+WRMLNWTLGIN+Q+L+ KAM+VCTTIRPDV+K +  + ND ++E K       EP+VP  IKD+A+HLELSI S  NSK    K++ +LL CGFGSRKYGFYLITLY+ T  LY
Sbjct:    1 MVFNTSFLAFIQGLKIFSLKTRRDDDYCDRLSHHHTAMFLLITSILISSNQYVGNPIHCWVPKEFSDPWQKYANNYCWIKNTYVLPPNLEPGSIPKLQERGELEINYYQWVPIVLLCQSLLFYLPSIIWRMLNWTLGINVQELVTKAMDVCTTIRPDVKKEESTESNDKTEEEK-------EPDVPNAIKDIAHHLELSIDSAKNSKSGMLKSICNLLCCGFGSRKYGFYLITLYLTTITLY 235
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BLAST of Innexin vs. TrEMBL
Match: A0A1I8IYE0 (Innexin OS=Macrostomum lignano OX=282301 GN=inx PE=3 SV=1)

HSP 1 Score: 306.22 bits (783), Expect = 4.739e-96
Identity = 169/440 (38.41%), Postives = 264/440 (60.00%), Query Frame = 1 
Query:   94 MVFNTGFLAFVQGLEIFSLKTRRDDDYCDRLSHHHTALFLLITSVLISSNQYVGSPIHCWVPKEFSGVWQKYANNYCWIKNTYIVPPNQKDGLIPKP-SERPELEINYYQWVPIVLLCQALLFYFPSIVWRMLNWTLGINIQDLINKAMNVCTTIRPDVQKPKPNDENDASKETKVPIQEDIEPEVPQEIKDMAYHLELSIQSESNSK----GSFAKTVRSLLFCGFGSRKYGFYLITLYIFTKLLYIINVVGQLFLLNSFIGTSYKLFGFQMLFNLAKGNDWKNTGHFPRITLCDFEIRNLGQRTNYTVQCVLPINLFNEKXXXXXXXXXXXVAILSVYSLFSWLLR-MIASQRFKFIQGLLEK-----RLKNWSTTDNNQLKRFIDEHLKTDGVFLIYLIYLNAGDLVTKELLDVMWYRYKKLSETKMSL-DSNYPEE 1377
            MV + G    ++ L+I S   R DDD+ DRL+H++TA+ +++ + +IS+ QYVG P+ CWVP +F+   ++YA NYCWI+NTY +P       IPK  S R + +I YYQWVP +L+CQALLFY P+IVWR+LNW  GIN      +A+N  T+   D Q   P+                      + I+ +A H+E +++ +   +    G   +     L C   SR++G +L  +Y   KLLYI N V Q FLLN+F+G+ Y+ FG+++L N+  G  W+ +G FPR+T+CDFEIR LG    +TVQCVL INLFNEKI++F+WFW+F+VA+ +V S F+WL +  +   R +F+   L       R  +      +QL+ F+ ++L+ DGVF++ ++ +NAG++++ E+   MW  Y+   +  +   ++N P++
Sbjct:    1 MVMDIGLFGTLRKLKIASSTLRIDDDFIDRLNHYYTAIVIVVFTFIISAKQYVGQPLQCWVPAQFTTAMEQYAENYCWIQNTYYLPLRHT---IPKEHSHRNDRKIGYYQWVPFMLVCQALLFYLPNIVWRLLNWESGINF-----RAINRMTS---DAQNVNPDSRG-------------------KTIRAIARHIEDALRYQKRERRDCLGQLRQAANKFLLC---SRRHGVFLSLMYFLVKLLYICNCVCQFFLLNAFLGSPYQFFGWELLINMISGVTWEESGQFPRVTMCDFEIRVLGNLHRHTVQCVLVINLFNEKIFVFLWFWLFLVAVATVMSFFTWLYKHALPPMRHQFVLSSLRMADSNVRRDSRDVAVRHQLENFVSQNLRCDGVFVLRMLAINAGEIISAEVAREMWLSYRGDCKRPLQTGNANGPDQ 407
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BLAST of Innexin vs. TrEMBL
Match: A0A1S3JZA2 (Innexin OS=Lingula unguis OX=7574 GN=LOC106177202 PE=3 SV=1)

HSP 1 Score: 299.671 bits (766), Expect = 1.857e-93
Identity = 164/417 (39.33%), Postives = 247/417 (59.23%), Query Frame = 1 
Query:  157 RRDDDYCDRLSHHHTALFLLITSVLISSNQYVGSPIHCWVPKEFSGVWQKYANNYCWIKNTYIVPPNQKDGLIPKPSERPELEINYYQWVPIVLLCQALLFYFPSIVWRMLNWTLGINIQDLINKAMNVCTTIRPDVQKPKPNDENDASKETKVPIQEDIEPEVPQEIKDMAYHLELSIQSESNSKGSFAKTVRSLLFCGFGSRKYGFYLITLYIFTKLLYIINVVGQLFLLNSFIGTSYKLFGFQMLFNLAKGNDWKNTGHFPRITLCDFEIRNLGQRTN-YTVQCVLPINLFNEKXXXXXXXXXXXVAILSVYSLFSWLLRMIASQRFKFIQGLLEKRLKNWSTTDNNQLKRFIDEHLKTDGVFLIYLIYLNAGDLVTKELLDVMWYRYKKLSETKMSLDSNYPEEAQFL*KNTD 1404
            R+DDD+ +RL+H +TA+  ++ +V++ S  YVG PIHCW+P EF    + YANNYCWIKNTY +P  ++   IP  ++ P   I YYQWVPIV+L QALLFYFP + WR+++   GI++  ++     +              D  D  K   V         +   ++ M  +       +    GS    + ++L C    +++G YLI L+++ K LY+ N +GQLFLLN+F+GT + LFGF+ L N     DW  +G FPR+TLCDF++R LG   + +T+QCVLPINLFNEKIY+FIWFW+  V+ ++V+   +WL      +R ++I+  L K + +++T D ++ K+F+ E+LK DGVF+  LI  N  D++  E +  +W  YK   E K  L  N PE  Q + +NT+
Sbjct:   16 RQDDDFANRLNHRYTAIIFIVFAVVVMSASYVGDPIHCWMPGEFKDSHKSYANNYCWIKNTYYIPFEER---IPG-ADLPRPHIGYYQWVPIVMLLQALLFYFPVVFWRLMSGATGIDVHAIVKGVSGL--------------DYLDPEKRATV---------IKYLVRHMDRYFGHKKDRDRECFGSLRTIITNMLICCGVGKRFGNYLIFLFMWVKALYVANSIGQLFLLNTFLGTKFHLFGFEFLRNFMDEQDWTTSGRFPRVTLCDFKMRQLGGNIHRWTIQCVLPINLFNEKIYLFIWFWLIFVSAVTVFGFLTWLAVFFVGERKEYIKKNL-KLMGDYNTKDKDRFKKFVTEYLKVDGVFVCKLIQRNTNDVIVSEFVAELWDFYKNKPENKGMLGEN-PEVGQPMLENTE 403
[Close]
BLAST of Innexin vs. TrEMBL
Match: A0A2C9K7D2 (Innexin OS=Biomphalaria glabrata OX=6526 GN=inx PE=3 SV=1)

HSP 1 Score: 296.204 bits (757), Expect = 3.079e-92
Identity = 171/425 (40.24%), Postives = 253/425 (59.53%), Query Frame = 1 
Query:  136 EIFSLKTRRDDDYCDRLSHHHTALFLLITSVLISSNQYVGSPIHCWVPKEFSGVWQKYANNYCWIKNTYIVPPNQKDGLIPKP-SERPELEINYYQWVPIVLLCQALLFYFPSIVWRMLNWTLGINIQDLINKAMNVCTTIRPDVQKPKPNDENDASKETKVPIQEDIEPEVP-QEIKDMAYHLELSIQSESNSKGSFAKTVRSL------LFCGFGSRKYGFYLITLYIFTKLLYIINVVGQLFLLNSFIGTSYKLFGFQMLFNLAKGNDWKNTGHFPRITLCDFEIRNLGQRTNYTVQCVLPINLFNEKXXXXXXXXXXXVAILSVYSLFSWLLRMI-ASQRFKFIQGLLEKRLKNWSTTDNNQLKRFIDEHLKTDGVFLIYLIYLNAGDLVTKELLDVMW--YRYKKLSETKMSLDSNYPEE 1377
             + ++K R DDD  DR++H +T   L+I +V++S+ QYVG PI CW P +F+G    Y NN CWI NTY VP    D  +P+   +R E E+ YYQWVP++LL QAL+FY P I+WR+ N   GIN+  +++ A                   +DA  E          PEV  + IK +  H++  + ++  S+     T+R +      L CG   R+YG YLIT+Y+  K+LYI N +GQLF+LN+F+ + Y ++GFQ+L +L +G++W  +  FPR+T+CDF+IR +    +Y+VQCVLPINLFNEKIYIF+WFW+  V+ L+ YS  SWL +M+  S R  +I+  L+   +  S  D     RF  E+L+ DGVF + L+  N+ D+V  E++  +W  YR KK  + + +L SN  E 
Sbjct:   17 RVANVKVRNDDDLNDRVNHLYTTGILIIFTVVVSARQYVGDPIRCWCPAQFTGAHVDYTNNICWISNTYFVP---MDVSVPESVPKRRENELTYYQWVPVMLLIQALMFYIPCILWRLFNGQSGINVDRIVSLA-------------------SDAQYEA---------PEVRIRTIKYVVRHIDRCLDNQRESRHRCCVTLRHVLSVKMSLLCG---RRYGNYLITVYLVMKMLYIANAIGQLFMLNAFLASEYNMYGFQVLEDLIEGDEWTASRRFPRVTMCDFDIRQMTNNHHYSVQCVLPINLFNEKIYIFLWFWLVFVSALTCYSFISWLWQMVFPSSRIHYIRKFLKIMDRIGSGPDKKLATRFTMEYLRHDGVFTLRLVGKNSSDIVVAEIISGLWDLYRSKKSIQIRNTLPSNGHES 407
[Close]
BLAST of Innexin vs. Ensembl Cavefish
Match: panx2 (pannexin 2 [Source:NCBI gene;Acc:103040952])

HSP 1 Score: 48.9062 bits (115), Expect = 9.453e-6
Identity = 44/179 (24.58%), Postives = 75/179 (41.90%), Query Frame = 1 
Query:  178 DRLSHHHTALFLLITSVLISSNQYVGSPIHCWVPKEFSGVWQKYANNYCWIKNTYIVPPNQKDGLIPKPSERPELEINYYQWVPIVLLCQALLFYFPSIVWRMLNWT-----LGINIQDLINKAMNVCTTIRPDVQKPKPNDENDASKETKVPIQEDIEPEVPQEIKDMAYHLELSIQS 699
            DR+    T +  ++   L+ +  +    I+C+ P  F+     YA  YCW +    VP     G+  +P +RP L    ++++P  LL  A + Y P++ W  L  T     L   +Q++ N          P ++K   +     S+  +  I E+ E E   E      +LE   QS
Sbjct:   52 DRVVTIGTVIIPILLVTLVFTRNFAEESIYCYTPHNFTRDQALYARGYCWTELRDAVP-----GV--EPQQRPSL--FEHKFLPYALLAFAGIMYIPALGWEFLASTRLTSELNFLLQEIDNCYHRAAEGRAPKIEKQIQSKGPGISERERREIIENAEKEKSPEQNLFEKYLERRGQS 221
[Close]
BLAST of Innexin vs. Planmine SMEST
Match: SMESG000056430.1 (SMESG000056430.1)

HSP 1 Score: 862.062 bits (2226), Expect = 0.000e+0
Identity = 431/432 (99.77%), Postives = 432/432 (100.00%), Query Frame = 1 
Query:   94 MVFNTGFLAFVQGLEIFSLKTRRDDDYCDRLSHHHTALFLLITSVLISSNQYVGSPIHCWVPKEFSGVWQKYANNYCWIKNTYIVPPNQKDGLIPKPSERPELEINYYQWVPIVLLCQALLFYFPSIVWRMLNWTLGINIQDLINKAMNVCTTIRPDVQKPKPNDENDASKETKVPIQEDIEPEVPQEIKDMAYHLELSIQSESNSKGSFAKTVRSLLFCGFGSRKYGFYLITLYIFTKLLYIINVVGQLFLLNSFIGTSYKLFGFQMLFNLAKGNDWKNTGHFPRITLCDFEIRNLGQRTNYTVQCVLPINLFNEKXXXXXXXXXXXVAILSVYSLFSWLLRMIASQRFKFIQGLLEKRLKNWSTTDNNQLKRFIDEHLKTDGVFLIYLIYLNAGDLVTKELLDVMWYRYKKLSETKMSLDSNYPEEAQFL 1389
            MVFNTGFLAFVQGLEIFSLKTRRDDDYCDRLSHHHTALFLLITSVLISSNQYVGSPIHCWVPKEFSGVWQKYANNYCWIKNTYIVPPNQKDGLIPKPSERPELEINYYQWVPIVLLCQALLFYFPSIVWRMLNWTLGINIQDLINKAMNVCTTIRPDVQKPKPNDENDASKETKVPIQEDIEPEVPQEIKDMAYHLELSIQSESNSKGSFAKTVRSLLFCGFGSRKYGFYLITLYIFTKLLYIINVVGQLFLLNSFIGTSYKLFGFQMLFNLAKGNDWKNTGHFPRITLCDFEIRNLGQRTNYTVQCVLPINLFNEKIYIFIWFWIFIVAILSVYSLFSWLLRMIASQRFKFIQGLLEKRLKNWSTTDNNQLKRFIDEHLKTDGVFLIYLIYLNAGDLVTKELLDVMWYRYKKLSETKMSLD+NYPEEAQFL
Sbjct:    1 MVFNTGFLAFVQGLEIFSLKTRRDDDYCDRLSHHHTALFLLITSVLISSNQYVGSPIHCWVPKEFSGVWQKYANNYCWIKNTYIVPPNQKDGLIPKPSERPELEINYYQWVPIVLLCQALLFYFPSIVWRMLNWTLGINIQDLINKAMNVCTTIRPDVQKPKPNDENDASKETKVPIQEDIEPEVPQEIKDMAYHLELSIQSESNSKGSFAKTVRSLLFCGFGSRKYGFYLITLYIFTKLLYIINVVGQLFLLNSFIGTSYKLFGFQMLFNLAKGNDWKNTGHFPRITLCDFEIRNLGQRTNYTVQCVLPINLFNEKIYIFIWFWIFIVAILSVYSLFSWLLRMIASQRFKFIQGLLEKRLKNWSTTDNNQLKRFIDEHLKTDGVFLIYLIYLNAGDLVTKELLDVMWYRYKKLSETKMSLDNNYPEEAQFL 432
[Close]
BLAST of Innexin vs. Planmine SMEST
Match: SMESG000056430.1 (SMESG000056430.1)

HSP 1 Score: 695.656 bits (1794), Expect = 0.000e+0
Identity = 354/428 (82.71%), Postives = 379/428 (88.55%), Query Frame = 1 
Query:  109 GFLAFVQGLEIFSLKTRRDDDYCDRLSHHHTALFLLITSVLISSNQYVGSPIHCWVPKEFSGVWQKYANNYCWIKNTYIVPPNQKDGLIPKP-SERPELEINYYQWVPIVLLCQALLFYFPSIVWRMLNWTLGINIQDLINKAMNVCTTIRPDVQKPKPNDENDASKETKVPIQEDIEPEVPQEIKDMAYHLELSIQSESNSKGSFAKTVRSLLFCGFGSRKYGFYLITLYIFTKLLYIINVVGQLFLLNSFIGTSYKLFGFQMLFNLAKGNDWKNTGHFPRITLCDFEIRNLGQRTNYTVQCVLPINLFNEKXXXXXXXXXXXVAILSVYSLFSWLLRMIASQRFKFIQGLLEKRLKNWSTTDNNQLKRFIDEHLKTDGVFLIYLIYLNAGDLVTKELLDVMWYRYKKLSETKMSLDSNYPEEAQFL 1389
            G  AF +  +I   +  RDDD+ DR++H +T++ L+I ++ IS+ QY+   I CW+P EFS  W +YA NYCWI+NTY +P    D  +PK    R   +++YYQWVP VL  Q  LFYFP   WR++NW  GINIQDLINKAMNVCTTIRPDVQKPKPNDENDASKETKVPIQEDIEPEVPQEIKDMAYHLELSIQSESNSKGSFAKTVRSLLFCGFGSRKYGFYLITLYIFTKLLYIINVVGQLFLLNSFIGTSYKLFGFQMLFNLAKGNDWKNTGHFPRITLCDFEIRNLGQRTNYTVQCVLPINLFNEKIYIFIWFWIFIVAILSVYSLFSWLLRMIASQRFKFIQGLLEKRLKNWSTTDNNQLKRFIDEHLKTDGVFLIYLIYLNAGDLVTKELLDVMWYRYKKLSETKMSLD+NYPEEAQFL
Sbjct:    3 GLFAFSKSFDIL-YRRGRDDDFFDRINHWYTSIVLVIMAIFISTKQYLNDSITCWMPVEFSKPWVQYAENYCWIQNTYYIP---HDTELPKSHGYRTTSQLSYYQWVPYVLALQTFLFYFPRAFWRLMNWQSGINIQDLINKAMNVCTTIRPDVQKPKPNDENDASKETKVPIQEDIEPEVPQEIKDMAYHLELSIQSESNSKGSFAKTVRSLLFCGFGSRKYGFYLITLYIFTKLLYIINVVGQLFLLNSFIGTSYKLFGFQMLFNLAKGNDWKNTGHFPRITLCDFEIRNLGQRTNYTVQCVLPINLFNEKIYIFIWFWIFIVAILSVYSLFSWLLRMIASQRFKFIQGLLEKRLKNWSTTDNNQLKRFIDEHLKTDGVFLIYLIYLNAGDLVTKELLDVMWYRYKKLSETKMSLDNNYPEEAQFL 426
[Close]
BLAST of Innexin vs. Planmine SMEST
Match: SMESG000035987.1 (SMESG000035987.1)

HSP 1 Score: 297.36 bits (760), Expect = 2.986e-95
Identity = 164/415 (39.52%), Postives = 245/415 (59.04%), Query Frame = 1 
Query:  121 FVQGLEIFS---LKTRRDDDYCDRLSHHHTALFLLITSVLISSNQYVGSPIHCWVPKEFSGVWQKYANNYCWIKNTYIVPPNQKDGLIPKPSE-RPELEINYYQWVPIVLLCQALLFYFPSIVWRMLNWTLGINIQDLINKAMNVCTTIRPDVQKPKPNDENDASKETKVPIQEDIEPEVPQEIKDMAYHLELSIQSESNSKGSFAKTVRSLL---FCGFGSRKYGFYLITLYIFTKLLYIINVVGQLFLLNSFIGTSYKLFGFQMLFNLAKGNDWKNTGHFPRITLCDFEIRNLGQRTNYTVQCVLPINLFNEKXXXXXXXXXXXVAILSVYSLFSWLLRMIAS-QRFKFIQGLLEKRLKNWSTTDNNQLKRFIDEHLKTDGVFLIYLIYLNAGDLVTKELLDVMWYRYKKLSE 1341
            F  GL  F     K RRDDD  DR +H  T + L+  S+++S+ QYVG PI CWVP EF+   ++YA + CW+ +TY + P Q  G IP+ ++ R E +I YYQWVP +L+ QA+LF FP  VWR+LNW  G+NI  +I+ A +  T +  D ++ K N                        +  +  H++ +++ +   +       R  L   FC +  R+YG YL+ +Y   K LYI+NV+GQ FL+N F+GT+Y  +G  +++ L+ GN+W  +G+FPR+T+CDF IR L  +  YTVQCVLPINLFNEKI+IF+WFW   +AI++V+S   W  + +   QR+ FI+  L  +       D  +L  FID  L+ DGVF++ L+ LN GDL+  E+ + +W R+K+ + 
Sbjct:    5 FFSGLSKFKNDVGKFRRDDDQSDRFNHFFTTILLVCFSLVVSTRQYVGKPIACWVPTEFTSSQEEYAESICWVSSTYFINPYQ--GSIPENTQQREEKKILYYQWVPFILMLQAILFNFPCCVWRLLNWQSGLNISAIIDIAGD--TEMIKDYEQRKAN------------------------LDFITRHIDDTLRIQREYRNGCTVQCRHCLAQHFCMWFGRRYGNYLVCVYTICKSLYILNVIGQFFLMNRFLGTNYTFYGLDLIYQLSIGNEWTESGNFPRVTMCDFNIRKLANQHRYTVQCVLPINLFNEKIFIFLWFWFVFIAIITVHSFIHWTSKSVCRIQRYNFIRKFLVLKDALQEAGDRKKLYAFIDLFLQQDGVFILRLLALNCGDLIAAEITEYLWCRFKECAR 391
[Close]
BLAST of Innexin vs. Planmine SMEST
Match: SMESG000046667.1 (SMESG000046667.1)

HSP 1 Score: 287.345 bits (734), Expect = 1.436e-91
Identity = 161/405 (39.75%), Postives = 240/405 (59.26%), Query Frame = 1 
Query:  160 RDDDYCDRLSHHHTALFLLITSVLISSNQYVGSPIHCWVPKEFSGVWQKYANNYCWIKNTYIVPPNQKDGLIPKP-SERPELEINYYQWVPIVLLCQALLFYFPSIVWRMLNWTLGINIQDLINKAMNVCTTIRPDVQKPKPNDENDASKETKVPIQEDIEPEVPQEIKDMAYHLELSIQSESNSKGSFAKTVRSLLF---CGFGSRKYGFYLITLYIFTKLLYIINVVGQLFLLNSFIGTSYKLFGFQMLFNLAKGNDWKNTGHFPRITLCDFEIRNLGQRTNYTVQCVLPINLFNEKXXXXXXXXXXXVAILSVYSLFSWLLRM-IASQRFKFIQGLLEKRLKNWSTTDNNQLKRFIDEHLKTDGVFLIYLIYLNAGDLVTKELLDVMWYRYK-KLSETKMSL 1356
            RDDD+ DRL+H  T+  L+I +++IS+ QY+G PI CWVP EFS   ++YA + CW+ +TY V P      IP+   +R + ++ YYQWVP +L+ QA LF  P I+WR+ NW  GIN+  ++  A +V   I  D +  K N                        +  +A+H++  + +   ++ +    +R+ +    C + S+ YG YLI LYI  K+LYI+NV+ Q F++N  +GT+Y  +GF ++  LA G  W  +GHFPRIT+CDFEIR L  +  YTVQCVLPIN+FNEKI+IF+WFW  +V+ ++V S  S   ++ +   R  F+   L+ R K   T   N+ + F+++HL+ DGVFL+ L+  NAGDL+  E+ D +W  Y    SETK  L
Sbjct:   21 RDDDFADRLNHTFTSFLLVIFTLIISARQYIGKPIACWVPTEFSRAQEEYAESVCWVTSTYFVEPGVHS--IPQNIDDREDRKLLYYQWVPFILMGQAFLFNIPCIIWRLFNWQSGINLVSVMQVACDV--EIIKDRECRKVN------------------------VSYVAHHIDQCLNTRHVNRNTVGGRMRNFIAEKCCLWCSKMYGSYLICLYIICKMLYILNVISQFFIMNRVLGTNYTFYGFDLVKQLADGRMWHESGHFPRITMCDFEIRKLANKHRYTVQCVLPINMFNEKIFIFLWFWFVLVSAVTVSSFISLTYKIGLVYNRINFVCKFLKLRQKP-ETITKNKCRNFVEKHLRHDGVFLLRLLAQNAGDLIASEITDSLWRLYSDHKSETKTDL 396
[Close]
BLAST of Innexin vs. Planmine SMEST
Match: SMESG000046667.1 (SMESG000046667.1)

HSP 1 Score: 286.96 bits (733), Expect = 2.329e-91
Identity = 161/405 (39.75%), Postives = 240/405 (59.26%), Query Frame = 1 
Query:  160 RDDDYCDRLSHHHTALFLLITSVLISSNQYVGSPIHCWVPKEFSGVWQKYANNYCWIKNTYIVPPNQKDGLIPKP-SERPELEINYYQWVPIVLLCQALLFYFPSIVWRMLNWTLGINIQDLINKAMNVCTTIRPDVQKPKPNDENDASKETKVPIQEDIEPEVPQEIKDMAYHLELSIQSESNSKGSFAKTVRSLLF---CGFGSRKYGFYLITLYIFTKLLYIINVVGQLFLLNSFIGTSYKLFGFQMLFNLAKGNDWKNTGHFPRITLCDFEIRNLGQRTNYTVQCVLPINLFNEKXXXXXXXXXXXVAILSVYSLFSWLLRM-IASQRFKFIQGLLEKRLKNWSTTDNNQLKRFIDEHLKTDGVFLIYLIYLNAGDLVTKELLDVMWYRYK-KLSETKMSL 1356
            RDDD+ DRL+H  T+  L+I +++IS+ QY+G PI CWVP EFS   ++YA + CW+ +TY V P      IP+   +R + ++ YYQWVP +L+ QA LF  P I+WR+ NW  GIN+  ++  A +V   I  D +  K N                        +  +A+H++  + +   ++ +    +R+ +    C + S+ YG YLI LYI  K+LYI+NV+ Q F++N  +GT+Y  +GF ++  LA G  W  +GHFPRIT+CDFEIR L  +  YTVQCVLPIN+FNEKI+IF+WFW  +V+ ++V S  S   ++ +   R  F+   L+ R K   T   N+ + F+++HL+ DGVFL+ L+  NAGDL+  E+ D +W  Y    SETK  L
Sbjct:   35 RDDDFADRLNHTFTSFLLVIFTLIISARQYIGKPIACWVPTEFSRAQEEYAESVCWVTSTYFVEPGVHS--IPQNIDDREDRKLLYYQWVPFILMGQAFLFNIPCIIWRLFNWQSGINLVSVMQVACDV--EIIKDRECRKVN------------------------VSYVAHHIDQCLNTRHVNRNTVGGRMRNFIAEKCCLWCSKMYGSYLICLYIICKMLYILNVISQFFIMNRVLGTNYTFYGFDLVKQLADGRMWHESGHFPRITMCDFEIRKLANKHRYTVQCVLPINMFNEKIFIFLWFWFVLVSAVTVSSFISLTYKIGLVYNRINFVCKFLKLRQKP-ETITKNKCRNFVEKHLRHDGVFLLRLLAQNAGDLIASEITDSLWRLYSDHKSETKTDL 410
The following BLAST results are available for this feature:
BLAST of Innexin vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Innexin vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
unc-93.811e-8537.97Innexin unc-9 [Source:UniProtKB/Swiss-Prot;Acc:O0... [more]
inx-17.542e-8537.37Innexin [Source:UniProtKB/TrEMBL;Acc:Q17394][more]
inx-17.542e-8537.37Innexin [Source:UniProtKB/TrEMBL;Acc:Q17394][more]
inx-15.655e-8438.13Innexin [Source:UniProtKB/TrEMBL;Acc:Q17394][more]
inx-134.100e-8236.36Innexin [Source:UniProtKB/TrEMBL;Acc:O44887][more]
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BLAST of Innexin vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Inx24.624e-1625.45gene:FBgn0027108 transcript:FBtr0301860[more]
Inx24.624e-1625.45gene:FBgn0027108 transcript:FBtr0071005[more]
Inx24.624e-1625.45gene:FBgn0027108 transcript:FBtr0332314[more]
Inx24.624e-1625.45gene:FBgn0027108 transcript:FBtr0071006[more]
ogre8.830e-1324.12gene:FBgn0004646 transcript:FBtr0071037[more]
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BLAST of Innexin vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Innexin vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Innexin vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Innexin vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|O01393|UNC9_CAEEL4.848e-8437.97Innexin unc-9 OS=Caenorhabditis elegans OX=6239 GN... [more]
sp|Q03412|UNC7_CAEEL1.210e-7235.87Innexin unc-7 OS=Caenorhabditis elegans OX=6239 GN... [more]
sp|A8WVX4|INX19_CAEBR3.359e-6632.70Innexin-19 OS=Caenorhabditis briggsae OX=6238 GN=i... [more]
sp|Q23157|INX11_CAEEL1.052e-6433.25Innexin-11 OS=Caenorhabditis elegans OX=6239 GN=in... [more]
sp|O61715|INX19_CAEEL2.351e-6433.17Innexin-19 OS=Caenorhabditis elegans OX=6239 GN=in... [more]
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BLAST of Innexin vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
Q9NCL50.000e+064.61Innexin OS=Girardia tigrina OX=6162 GN=Panx1 PE=2 ... [more]
Q2L6M21.372e-12773.55Innexin OS=Dugesia japonica OX=6161 GN=inx1 PE=2 S... [more]
A0A1I8IYE04.739e-9638.41Innexin OS=Macrostomum lignano OX=282301 GN=inx PE... [more]
A0A1S3JZA21.857e-9339.33Innexin OS=Lingula unguis OX=7574 GN=LOC106177202 ... [more]
A0A2C9K7D23.079e-9240.24Innexin OS=Biomphalaria glabrata OX=6526 GN=inx PE... [more]
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BLAST of Innexin vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 1
Match NameE-valueIdentityDescription
panx29.453e-624.58pannexin 2 [Source:NCBI gene;Acc:103040952][more]
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BLAST of Innexin vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Innexin vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Innexin vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Innexin vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Innexin vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000056430.10.000e+099.77SMESG000056430.1[more]
SMESG000056430.10.000e+082.71SMESG000056430.1[more]
SMESG000035987.12.986e-9539.52SMESG000035987.1[more]
SMESG000046667.11.436e-9139.75SMESG000046667.1[more]
SMESG000046667.12.329e-9139.75SMESG000046667.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30028401 ID=SMED30028401|Name=Innexin|organism=Schmidtea mediterranea sexual|type=transcript|length=1485bp
TTGTTTTAATAGCTTATTAGATTAATCTTTGATACCAAATTAATTGACCG
CTAAATTCAATTTTTTTTTCAAAATATAAAATAAGAAATAATAATGGTTT
TTAATACTGGATTTTTAGCCTTTGTACAGGGGCTAGAAATTTTCTCATTG
AAAACAAGACGAGACGATGATTATTGTGATCGGTTGAGCCACCATCATAC
AGCTTTGTTTTTATTGATAACATCAGTGCTAATAAGTTCAAATCAATATG
TGGGCAGCCCGATCCATTGTTGGGTACCGAAAGAATTTTCAGGTGTCTGG
CAGAAATATGCTAATAACTATTGTTGGATTAAAAACACATATATCGTTCC
GCCGAACCAAAAAGATGGGTTAATCCCAAAACCCAGTGAAAGACCAGAGT
TAGAAATCAACTACTATCAATGGGTACCAATTGTGCTTCTATGTCAGGCC
TTGTTGTTTTATTTCCCCTCAATCGTATGGAGAATGTTAAACTGGACATT
GGGAATCAACATTCAAGATTTGATCAACAAGGCGATGAATGTTTGCACGA
CAATCAGACCAGACGTACAGAAACCAAAACCTAATGACGAAAATGATGCT
AGTAAAGAAACTAAAGTACCGATACAAGAAGACATTGAGCCAGAAGTCCC
ACAAGAAATCAAGGACATGGCTTATCACTTAGAGCTTTCAATTCAGTCAG
AATCTAATTCAAAAGGAAGCTTTGCCAAAACTGTTAGGAGTTTATTATTT
TGTGGGTTTGGCAGTCGTAAATATGGGTTTTATTTAATAACGCTTTATAT
CTTTACGAAACTGCTATATATTATTAATGTCGTAGGTCAGTTATTTTTAT
TGAACAGTTTTATTGGAACCTCATACAAATTGTTTGGATTTCAAATGCTT
TTTAATCTAGCCAAAGGAAATGACTGGAAAAACACAGGACATTTTCCTCG
GATTACTTTGTGTGATTTTGAAATTAGGAATCTTGGACAACGAACTAACT
ACACGGTTCAATGCGTTTTACCAATCAACCTTTTCAATGAGAAGATTTAT
ATTTTCATTTGGTTTTGGATTTTCATTGTTGCAATTCTGTCTGTTTACAG
TTTATTCAGCTGGCTATTACGAATGATTGCCAGTCAGAGATTTAAATTCA
TTCAAGGTTTATTAGAAAAACGACTGAAAAACTGGTCGACTACTGACAAT
AACCAACTGAAAAGATTTATAGATGAACACTTGAAAACCGACGGAGTATT
TTTGATTTATCTGATCTATCTTAATGCCGGCGACCTTGTGACCAAGGAAT
TGTTAGACGTTATGTGGTATCGGTACAAAAAGCTTTCAGAAACAAAGATG
TCACTTGATAGCAACTACCCAGAAGAGGCTCAATTTTTATAAAAAAACAC
TGACATAATATTGTATTTTTTGACATTTTAATGTTAATTATATTTCATTC
ATAAACTATCAAATAAAACTGAAATTAAAAAAAAA
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protein sequence of SMED30028401-orf-1

>SMED30028401-orf-1 ID=SMED30028401-orf-1|Name=SMED30028401-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=433bp
MVFNTGFLAFVQGLEIFSLKTRRDDDYCDRLSHHHTALFLLITSVLISSN
QYVGSPIHCWVPKEFSGVWQKYANNYCWIKNTYIVPPNQKDGLIPKPSER
PELEINYYQWVPIVLLCQALLFYFPSIVWRMLNWTLGINIQDLINKAMNV
CTTIRPDVQKPKPNDENDASKETKVPIQEDIEPEVPQEIKDMAYHLELSI
QSESNSKGSFAKTVRSLLFCGFGSRKYGFYLITLYIFTKLLYIINVVGQL
FLLNSFIGTSYKLFGFQMLFNLAKGNDWKNTGHFPRITLCDFEIRNLGQR
TNYTVQCVLPINLFNEKIYIFIWFWIFIVAILSVYSLFSWLLRMIASQRF
KFIQGLLEKRLKNWSTTDNNQLKRFIDEHLKTDGVFLIYLIYLNAGDLVT
KELLDVMWYRYKKLSETKMSLDSNYPEEAQFL*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000026gut
PLANA:0000070intestinal phagocyte
Vocabulary: INTERPRO
TermDefinition
IPR000990Innexin
Vocabulary: cellular component
TermDefinition
GO:0005921gap junction
GO:0005886plasma membrane
GO:0016020membrane
GO:0016021integral component of membrane
GO:0030054cell junction
Vocabulary: biological process
TermDefinition
GO:0006810transport
GO:0006811ion transport
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR000990InnexinPRINTSPR01262INNEXINcoord: 76..85
score: 56.0
coord: 107..129
score: 57.74
coord: 235..249
score: 48.8
coord: 48..59
score: 54.33
coord: 307..323
score: 63.76
coord: 283..292
score: 69.6
IPR000990InnexinPFAMPF00876Innexincoord: 25..411
e-value: 8.7E-112
score: 373.9
IPR000990InnexinPANTHERPTHR11893INNEXINcoord: 19..422
IPR000990InnexinPROSITEPS51013PANNEXINcoord: 20..417
score: 37.222
NoneNo IPR availableTMHMMTMhelixcoord: 231..253
NoneNo IPR availableTMHMMTMhelixcoord: 320..342
NoneNo IPR availableTMHMMTMhelixcoord: 107..129