Calcium-activated potassium channel subunit alpha-1

Overview


Name	Calcium-activated potassium channel subunit alpha-1
Smed ID	SMED30028391
Length (bp)	3119

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of Calcium-activated potassium channel subunit alpha-1 (SMED30028391) t-SNE clustered cells

Violin plots show distribution of expression levels for Calcium-activated potassium channel subunit alpha-1 (SMED30028391) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Calcium-activated potassium channel subunit alpha-1 (SMED30028391) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30028391

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 3

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication
head region	SMED30028391	SMESG000040067.1	SmedASXL_016063	SmedAsxl_ww_GCZZ01	PMID:27034770 Currie et al., 2016
X2 cell	SMED30028391	SMESG000040067.1	SmedASXL_016063	SmedAsxl_ww_GCZZ01	PMID:26114597 Zhu et al., 2015
head region	SMED30028391	SMESG000040067.1	dd_Smed_v6_15810_0_1	dd_Smed_v6	PMID:28171748 Stückemann et al., 2017

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Homology

[Close]

BLAST of Calcium-activated potassium channel subunit alpha-1 vs. Ensembl Human
Match: KCNMA1 (potassium calcium-activated channel subfamily M alpha 1 [Source:HGNC Symbol;Acc:HGNC:6284])

HSP 1 Score: 348.591 bits (893), Expect = 5.504e-102
Identity = 270/975 (27.69%), Postives = 448/975 (45.95%), Query Frame = 2

Query:  323 IMISKSTIVGRFLNFVKLISQLTSWGIFVVFTFNQVNANYLIGDCFDVEGANLQWIDFALNIFCLFHFTLRAFAANDILKFWIQPTTMIEITVIPNILLTSFLPVRRQGFSFLRIYYLRELCNTIAVSFGILKVNSKFEMTKVIFYIISLWLISAGLFHMFEGIGNFWEIPLFNQQLSFWRCCYFMLVTISTVGFGSVNPLTIFGRIVVLVYIIYGITMFVTVLPNVIRTIQNLK-YKNRYISKGNERHIIVCGKFESLTIIAFLKAF-KRERFKGSVRNVKIVTMNKDLYDENLLMYMKRFSNPIKYLIGNLSNRKDLKRVNIQKAKLSVILSTPFTNKISEDDIDNIMTAMILKSQRKNMRTIVQLHLYSNKVLLKMSPMWNQNRSDIILCIDELKLGLMAYNCLTPGIATLVINLVTFTKSKSVSE-LWRKDYENGLKVLLYNVQFSDCFHGMSCLEVALIVYKLWDVCLLAIKCVNKSTDDYVLINPMIENIKIDTDSMIAIVMARDEASSNKLIFYCSKCSPQ--NQSEICQCYLEATKNSPRGHYESNLQFENQRINESFRSAYEF----PTIDSKSEEID--INSYTGLDRTGSFYWAPEPNFEDVCLDIETAESRSLSDHILVCLCG-IGHGTIDLCNFMMPLRFQNLQNSELRTIVILGNKSYFEADKWTNIKNFPMFLIIDGSPIQSRDLRAAGLLKCHTCVIINGNDKTV---GFSDKSAIICATLIRSMRKLNKLKI---------------------PIMIEIRKDEIAH--HFSSIHSHNNDSKVS-------------VQHSEPFARGILFTNSTVYSCIYTVYKNPDTFSFIKTLLNGRYSDEIESMFGSGVGL-----LPQXXXXXXXXXXXXIIKLFSVIQPPLNEISRVYDGILDYACLFEWALMEKRILCLGLYRLNFGR--------NRYVFTHPEKSTEIFSTDQVYCCVSSD 3055
            +MIS  T+ GR L  V L+  L S G  V++  +  N    I  C +        ID A N+F L +F LR  AAND L FW++  ++++   +P + ++ +L     G  FLR   L +    +     ILK ++  ++  ++   IS WL +AG  H+ E  G+ WE    NQ L++W C Y ++VT+STVG+G V   T  GR+ ++ +I+ G+ MF + +P +I  I N K Y   Y +    +HI+VCG     ++  FLK F  ++R      NV+IV ++    +  L    KR    +++  G++ N  DL RV I+ A   +IL+  +      +D  NIM  + +K+    +R I Q+  Y NK  L   P WN    D  +C+ ELKLG +A +CL  G++T++ NL +      + E  W+K Y  G+   +Y    S  F G+S   V  + +    + ++AI+  + + +  +LINP   ++KI  +  +   +A D     +  FYC  C     +   I +C  +  ++          +  N  +  S  ++ +     P +   +++ID   ++    D TG F+W      E V L    A    LS H++VC+ G +    I L N +MPLR  N    EL+ IV +G+  Y + + W  + NFP   I+ G+P+   DLRA  +  C  CVI++ N   +      DK  I+ +  I+SM+  + + +                     P+   +R+  I    +   I    ND+ V              +  ++PFA G  F  S + S +   Y N +  + I+TL+ G  + E+E++      L      PQ  ++ +R      +   +++  P  ++    DG   Y  LF  AL    +LC G+YRL             RYV T+P    E+  TD ++C +  D
Sbjct:  168 VMISAQTLTGRVL--VVLVFAL-SIGALVIYFIDSSNP---IESCQNFYKDFTLQIDMAFNVFFLLYFGLRFIAANDKLWFWLEVNSVVDFFTVPPVFVSVYLNRSWLGLRFLRALRLIQFSEILQF-LNILKTSNSIKLVNLLSIFISTWLTAAGFIHLVENSGDPWENFQNNQALTYWECVYLLMVTMSTVGYGDVYAKTTLGRLFMVFFILGGLAMFASYVPEIIELIGNRKKYGGSYSAVSGRKHIVVCGHITLESVSNFLKDFLHKDR---DDVNVEIVFLHNISPNLELEALFKRHFTQVEFYQGSVLNPHDLARVKIESADACLILANKYCADPDAEDASNIMRVISIKNYHPKIRIITQMLQYHNKAHLLNIPSWNWKEGDDAICLAELKLGFIAQSCLAQGLSTMLANLFSMRSFIKIEEDTWQKYYLEGVSNEMYTEYLSSAFVGLSFPTVCELCFVKLKLLMIAIEYKSANRESRILINPG-NHLKIQ-EGTLGFFIASDAKEVKRAFFYCKACHDDITDPKRIKKCGCKRLEDEQPSTLSPKKKQRNGGMRNSPNTSPKLMRHDPLLIPGNDQIDNMDSNVKKYDSTGMFHWCAPKEIEKVILTRSEAAMTVLSGHVVVCIFGDVSSALIGLRNLVMPLRASNFHYHELKHIVFVGSIEYLKRE-WETLHNFPKVSILPGTPLSRADLRAVNINLCDMCVILSANQNNIDDTSLQDKECILASLNIKSMQFDDSIGVLQANSQGFTPPGMDRSSPDNSPVHGMLRQPSITTGVNIPIITELVNDTNVQFLDQDDDDDPDTELYLTQPFACGTAFAVSVLDSLMSATYFNDNILTLIRTLVTGGATPELEALIAEENALRGGYSTPQTLANRDRCR----VAQLALLDGPFADLG---DGGC-YGDLFCKALKTYNMLCFGIYRLRDAHLSTPSQCTKRYVITNPPYEFELVPTDLIFCLMQFD 1121

[Close]

BLAST of Calcium-activated potassium channel subunit alpha-1 vs. Ensembl Human
Match: KCNMA1 (potassium calcium-activated channel subfamily M alpha 1 [Source:HGNC Symbol;Acc:HGNC:6284])

HSP 1 Score: 348.591 bits (893), Expect = 5.685e-102
Identity = 276/979 (28.19%), Postives = 451/979 (46.07%), Query Frame = 2

Query:  323 IMISKSTIVGRFLNFVKLISQLTSWGIFVVFTFNQVNANYLIGDCFDVEGANLQWIDFALNIFCLFHFTLRAFAANDILKFWIQPTTMIEITVIPNILLTSFLPVRRQGFSFLRIYYLRELCNTIAVSFGILKVNSKFEMTKVIFYIISLWLISAGLFHMFEGIGNFWEIPLFNQQLSFWRCCYFMLVTISTVGFGSVNPLTIFGRIVVLVYIIYGITMFVTVLPNVIRTIQNLK-YKNRYISKGNERHIIVCGKFESLTIIAFLKAFKRERFKGSVRNVKIVTMNKDLYDENLLMYMKRFSNPIKYLIGNLSNRKDLKRVNIQKAKLSVILSTPFTNKISEDDIDNIMTAMILKSQRKNMRTIVQLHLYSNKVLLKMSPMWNQNRSDIILCIDELKLGLMAYNCLTPGIATLVINLVTFTKSKSVSE-LWRKDYENGLKVLLYNVQFSDCFHGMSCLEVALIVYKLWDVCLLAIKCVNKSTDDYVLINPMIENIKIDTDSMIAIVMARDEASSNKLIFYCSKC----SPQNQSEICQC----YLEATKNS---PRGHYESNLQFENQRINESFRSAYEFPTIDSKSEEID--INSYTGLDRTGSFYWAPEPNFEDVCLDIETAESRSLSDHILVCLCG-IGHGTIDLCNFMMPLRFQNLQNSELRTIVILGNKSYFEADKWTNIKNFPMFLIIDGSPIQSRDLRAAGLLKCHTCVIINGNDKTV---GFSDKSAIICATLIRSMRKLNKLKI---------------------PIMIEIRKDEIAH--HFSSIHSHNNDSKVS-------------VQHSEPFARGILFTNSTVYSCIYTVYKNPDTFSFIKTLLNGRYSDEIESMFGSGVGL-----LPQXXXXXXXXXXXXIIKLFSVIQPPLNEISRVYDGILDYACLFEWALMEKRILCLGLYRLNFGR--------NRYVFTHPEKSTEIFSTDQVYCCVSSD 3055
            +MIS  T+ GR L  V L+  L S G  V++  +  N    I  C +        ID A N+F L +F LR  AAND L FW++  ++++   +P + ++ +L     G  FLR   L +    +     ILK ++  ++  ++   IS WL +AG  H+ E  G+ WE    NQ L++W C Y ++VT+STVG+G V   T  GR+ ++ +I+ G+ MF + +P +I  I N K Y   Y +    +HI+VCG     ++  FLK F  +  +  V NV+IV ++    +  L    KR    +++  G++ N  DL RV I+ A   +IL+  +      +D  NIM  + +K+    +R I Q+  Y NK  L   P WN    D  +C+ ELKLG +A +CL  G++T++ NL +      + E  W+K Y  G+   +Y    S  F G+S   V  + +    + ++AI+  + + +  +LINP   ++KI  +  +   +A D     +  FYC  C    +   + + C C    Y E  + S   P+   + N    N   N S +     P +   +++ID   ++    D TG F+W      E V L    A    LS H++VC+ G +    I L N +MPLR  N    EL+ IV +G+  Y + + W  + NFP   I+ G+P+   DLRA  +  C  CVI++ N   +      DK  I+ +  I+SM+  + + +                     P+   +R+  I    +   I    ND+ V              +  ++PFA G  F  S + S +   Y N +  + I+TL+ G  + E+E++      L      PQ  ++ +R      +   +++  P  ++    DG   Y  LF  AL    +LC G+YRL             RYV T+P    E+  TD ++C +  D
Sbjct:  168 VMISAQTLTGRVL--VVLVFAL-SIGALVIYFIDSSNP---IESCQNFYKDFTLQIDMAFNVFFLLYFGLRFIAANDKLWFWLEVNSVVDFFTVPPVFVSVYLNRSWLGLRFLRALRLIQFSEILQF-LNILKTSNSIKLVNLLSIFISTWLTAAGFIHLVENSGDPWENFQNNQALTYWECVYLLMVTMSTVGYGDVYAKTTLGRLFMVFFILGGLAMFASYVPEIIELIGNRKKYGGSYSAVSGRKHIVVCGHITLESVSNFLKDFLHKD-RDDV-NVEIVFLHNISPNLELEALFKRHFTQVEFYQGSVLNPHDLARVKIESADACLILANKYCADPDAEDASNIMRVISIKNYHPKIRIITQMLQYHNKAHLLNIPSWNWKEGDDAICLAELKLGFIAQSCLAQGLSTMLANLFSMRSFIKIEEDTWQKYYLEGVSNEMYTEYLSSAFVGLSFPTVCELCFVKLKLLMIAIEYKSANRESRILINPG-NHLKIQ-EGTLGFFIASDAKEVKRAFFYCKACHDDITDPKRIKKCGCKRLIYFEDEQPSTLSPKKK-QRNGGMRNSP-NTSPKLMRHDPLLIPGNDQIDNMDSNVKKYDSTGMFHWCAPKEIEKVILTRSEAAMTVLSGHVVVCIFGDVSSALIGLRNLVMPLRASNFHYHELKHIVFVGSIEYLKRE-WETLHNFPKVSILPGTPLSRADLRAVNINLCDMCVILSANQNNIDDTSLQDKECILASLNIKSMQFDDSIGVLQANSQGFTPPGMDRSSPDNSPVHGMLRQPSITTGVNIPIITELVNDTNVQFLDQDDDDDPDTELYLTQPFACGTAFAVSVLDSLMSATYFNDNILTLIRTLVTGGATPELEALIAEENALRGGYSTPQTLANRDRCR----VAQLALLDGPFADLG---DGGC-YGDLFCKALKTYNMLCFGIYRLRDAHLSTPSQCTKRYVITNPPYEFELVPTDLIFCLMQFD 1124

[Close]

BLAST of Calcium-activated potassium channel subunit alpha-1 vs. Ensembl Human
Match: KCNMA1 (potassium calcium-activated channel subfamily M alpha 1 [Source:HGNC Symbol;Acc:HGNC:6284])

HSP 1 Score: 348.591 bits (893), Expect = 5.703e-102
Identity = 270/975 (27.69%), Postives = 448/975 (45.95%), Query Frame = 2

Query:  323 IMISKSTIVGRFLNFVKLISQLTSWGIFVVFTFNQVNANYLIGDCFDVEGANLQWIDFALNIFCLFHFTLRAFAANDILKFWIQPTTMIEITVIPNILLTSFLPVRRQGFSFLRIYYLRELCNTIAVSFGILKVNSKFEMTKVIFYIISLWLISAGLFHMFEGIGNFWEIPLFNQQLSFWRCCYFMLVTISTVGFGSVNPLTIFGRIVVLVYIIYGITMFVTVLPNVIRTIQNLK-YKNRYISKGNERHIIVCGKFESLTIIAFLKAF-KRERFKGSVRNVKIVTMNKDLYDENLLMYMKRFSNPIKYLIGNLSNRKDLKRVNIQKAKLSVILSTPFTNKISEDDIDNIMTAMILKSQRKNMRTIVQLHLYSNKVLLKMSPMWNQNRSDIILCIDELKLGLMAYNCLTPGIATLVINLVTFTKSKSVSE-LWRKDYENGLKVLLYNVQFSDCFHGMSCLEVALIVYKLWDVCLLAIKCVNKSTDDYVLINPMIENIKIDTDSMIAIVMARDEASSNKLIFYCSKCSPQ--NQSEICQCYLEATKNSPRGHYESNLQFENQRINESFRSAYEF----PTIDSKSEEID--INSYTGLDRTGSFYWAPEPNFEDVCLDIETAESRSLSDHILVCLCG-IGHGTIDLCNFMMPLRFQNLQNSELRTIVILGNKSYFEADKWTNIKNFPMFLIIDGSPIQSRDLRAAGLLKCHTCVIINGNDKTV---GFSDKSAIICATLIRSMRKLNKLKI---------------------PIMIEIRKDEIAH--HFSSIHSHNNDSKVS-------------VQHSEPFARGILFTNSTVYSCIYTVYKNPDTFSFIKTLLNGRYSDEIESMFGSGVGL-----LPQXXXXXXXXXXXXIIKLFSVIQPPLNEISRVYDGILDYACLFEWALMEKRILCLGLYRLNFGR--------NRYVFTHPEKSTEIFSTDQVYCCVSSD 3055
            +MIS  T+ GR L  V L+  L S G  V++  +  N    I  C +        ID A N+F L +F LR  AAND L FW++  ++++   +P + ++ +L     G  FLR   L +    +     ILK ++  ++  ++   IS WL +AG  H+ E  G+ WE    NQ L++W C Y ++VT+STVG+G V   T  GR+ ++ +I+ G+ MF + +P +I  I N K Y   Y +    +HI+VCG     ++  FLK F  ++R      NV+IV ++    +  L    KR    +++  G++ N  DL RV I+ A   +IL+  +      +D  NIM  + +K+    +R I Q+  Y NK  L   P WN    D  +C+ ELKLG +A +CL  G++T++ NL +      + E  W+K Y  G+   +Y    S  F G+S   V  + +    + ++AI+  + + +  +LINP   ++KI  +  +   +A D     +  FYC  C     +   I +C  +  ++          +  N  +  S  ++ +     P +   +++ID   ++    D TG F+W      E V L    A    LS H++VC+ G +    I L N +MPLR  N    EL+ IV +G+  Y + + W  + NFP   I+ G+P+   DLRA  +  C  CVI++ N   +      DK  I+ +  I+SM+  + + +                     P+   +R+  I    +   I    ND+ V              +  ++PFA G  F  S + S +   Y N +  + I+TL+ G  + E+E++      L      PQ  ++ +R      +   +++  P  ++    DG   Y  LF  AL    +LC G+YRL             RYV T+P    E+  TD ++C +  D
Sbjct:  168 VMISAQTLTGRVL--VVLVFAL-SIGALVIYFIDSSNP---IESCQNFYKDFTLQIDMAFNVFFLLYFGLRFIAANDKLWFWLEVNSVVDFFTVPPVFVSVYLNRSWLGLRFLRALRLIQFSEILQF-LNILKTSNSIKLVNLLSIFISTWLTAAGFIHLVENSGDPWENFQNNQALTYWECVYLLMVTMSTVGYGDVYAKTTLGRLFMVFFILGGLAMFASYVPEIIELIGNRKKYGGSYSAVSGRKHIVVCGHITLESVSNFLKDFLHKDR---DDVNVEIVFLHNISPNLELEALFKRHFTQVEFYQGSVLNPHDLARVKIESADACLILANKYCADPDAEDASNIMRVISIKNYHPKIRIITQMLQYHNKAHLLNIPSWNWKEGDDAICLAELKLGFIAQSCLAQGLSTMLANLFSMRSFIKIEEDTWQKYYLEGVSNEMYTEYLSSAFVGLSFPTVCELCFVKLKLLMIAIEYKSANRESRILINPG-NHLKIQ-EGTLGFFIASDAKEVKRAFFYCKACHDDITDPKRIKKCGCKRLEDEQPSTLSPKKKQRNGGMRNSPNTSPKLMRHDPLLIPGNDQIDNMDSNVKKYDSTGMFHWCAPKEIEKVILTRSEAAMTVLSGHVVVCIFGDVSSALIGLRNLVMPLRASNFHYHELKHIVFVGSIEYLKRE-WETLHNFPKVSILPGTPLSRADLRAVNINLCDMCVILSANQNNIDDTSLQDKECILASLNIKSMQFDDSIGVLQANSQGFTPPGMDRSSPDNSPVHGMLRQPSITTGVNIPIITELVNDTNVQFLDQDDDDDPDTELYLTQPFACGTAFAVSVLDSLMSATYFNDNILTLIRTLVTGGATPELEALIAEENALRGGYSTPQTLANRDRCR----VAQLALLDGPFADLG---DGGC-YGDLFCKALKTYNMLCFGIYRLRDAHLSTPSQCTKRYVITNPPYEFELVPTDLIFCLMQFD 1121

[Close]

BLAST of Calcium-activated potassium channel subunit alpha-1 vs. Ensembl Human
Match: KCNMA1 (potassium calcium-activated channel subfamily M alpha 1 [Source:HGNC Symbol;Acc:HGNC:6284])

HSP 1 Score: 348.591 bits (893), Expect = 5.901e-102
Identity = 270/974 (27.72%), Postives = 448/974 (46.00%), Query Frame = 2

Query:  323 IMISKSTIVGRFLNFVKLISQLTSWGIFVVFTFNQVNANYLIGDCFDVEGANLQWIDFALNIFCLFHFTLRAFAANDILKFWIQPTTMIEITVIPNILLTSFLPVRRQGFSFLRIYYLRELCNTIAVSFGILKVNSKFEMTKVIFYIISLWLISAGLFHMFEGIGNFWEIPLFNQQLSFWRCCYFMLVTISTVGFGSVNPLTIFGRIVVLVYIIYGITMFVTVLPNVIRTIQNLK-YKNRYISKGNERHIIVCGKFESLTIIAFLKAFKRERFKGSVRNVKIVTMNKDLYDENLLMYMKRFSNPIKYLIGNLSNRKDLKRVNIQKAKLSVILSTPFTNKISEDDIDNIMTAMILKSQRKNMRTIVQLHLYSNKVLLKMSPMWNQNRSDIILCIDELKLGLMAYNCLTPGIATLVINLVTFTKSKSVSE-LWRKDYENGLKVLLYNVQFSDCFHGMSCLEVALIVYKLWDVCLLAIKCVNKSTDDYVLINPMIENIKIDTDSMIAIVMARDEASSNKLIFYCSKCSPQ--NQSEICQCYLEATKNSPRGHYESNLQFENQRINESFRSAYEF----PTIDSKSEEID--INSYTGLDRTGSFYWAPEPNFEDVCLDIETAESRSLSDHILVCLCG-IGHGTIDLCNFMMPLRFQNLQNSELRTIVILGNKSYFEADKWTNIKNFPMFLIIDGSPIQSRDLRAAGLLKCHTCVIINGNDKTV---GFSDKSAIICATLIRSMRKLNKLKI---------------------PIMIEIRKDEIAH--HFSSIHSHNNDSKVS-------------VQHSEPFARGILFTNSTVYSCIYTVYKNPDTFSFIKTLLNGRYSDEIESMFGSGVGL-----LPQXXXXXXXXXXXXIIKLFSVIQPPLNEISRVYDGILDYACLFEWALMEKRILCLGLYRLNFGR--------NRYVFTHPEKSTEIFSTDQVYCCVSSD 3055
            +MIS  T+ GR L  V L+  L S G  V++  +  N    I  C +        ID A N+F L +F LR  AAND L FW++  ++++   +P + ++ +L     G  FLR   L +    +     ILK ++  ++  ++   IS WL +AG  H+ E  G+ WE    NQ L++W C Y ++VT+STVG+G V   T  GR+ ++ +I+ G+ MF + +P +I  I N K Y   Y +    +HI+VCG     ++  FLK F  +  +  V NV+IV ++    +  L    KR    +++  G++ N  DL RV I+ A   +IL+  +      +D  NIM  + +K+    +R I Q+  Y NK  L   P WN    D  +C+ ELKLG +A +CL  G++T++ NL +      + E  W+K Y  G+   +Y    S  F G+S   V  + +    + ++AI+  + + +  +LINP   ++KI  +  +   +A D     +  FYC  C     +   I +C  +  ++          +  N  +  S  ++ +     P +   +++ID   ++    D TG F+W      E V L    A    LS H++VC+ G +    I L N +MPLR  N    EL+ IV +G+  Y + + W  + NFP   I+ G+P+   DLRA  +  C  CVI++ N   +      DK  I+ +  I+SM+  + + +                     P+   +R+  I    +   I    ND+ V              +  ++PFA G  F  S + S +   Y N +  + I+TL+ G  + E+E++      L      PQ  ++ +R      +   +++  P  ++    DG   Y  LF  AL    +LC G+YRL             RYV T+P    E+  TD ++C +  D
Sbjct:  168 VMISAQTLTGRVL--VVLVFAL-SIGALVIYFIDSSNP---IESCQNFYKDFTLQIDMAFNVFFLLYFGLRFIAANDKLWFWLEVNSVVDFFTVPPVFVSVYLNRSWLGLRFLRALRLIQFSEILQF-LNILKTSNSIKLVNLLSIFISTWLTAAGFIHLVENSGDPWENFQNNQALTYWECVYLLMVTMSTVGYGDVYAKTTLGRLFMVFFILGGLAMFASYVPEIIELIGNRKKYGGSYSAVSGRKHIVVCGHITLESVSNFLKDFLHKD-RDDV-NVEIVFLHNISPNLELEALFKRHFTQVEFYQGSVLNPHDLARVKIESADACLILANKYCADPDAEDASNIMRVISIKNYHPKIRIITQMLQYHNKAHLLNIPSWNWKEGDDAICLAELKLGFIAQSCLAQGLSTMLANLFSMRSFIKIEEDTWQKYYLEGVSNEMYTEYLSSAFVGLSFPTVCELCFVKLKLLMIAIEYKSANRESRILINPG-NHLKIQ-EGTLGFFIASDAKEVKRAFFYCKACHDDITDPKRIKKCGCKRLEDEQPSTLSPKKKQRNGGMRNSPNTSPKLMRHDPLLIPGNDQIDNMDSNVKKYDSTGMFHWCAPKEIEKVILTRSEAAMTVLSGHVVVCIFGDVSSALIGLRNLVMPLRASNFHYHELKHIVFVGSIEYLKRE-WETLHNFPKVSILPGTPLSRADLRAVNINLCDMCVILSANQNNIDDTSLQDKECILASLNIKSMQFDDSIGVLQANSQGFTPPGMDRSSPDNSPVHGMLRQPSITTGVNIPIITELVNDTNVQFLDQDDDDDPDTELYLTQPFACGTAFAVSVLDSLMSATYFNDNILTLIRTLVTGGATPELEALIAEENALRGGYSTPQTLANRDRCR----VAQLALLDGPFADLG---DGGC-YGDLFCKALKTYNMLCFGIYRLRDAHLSTPSQCTKRYVITNPPYEFELVPTDLIFCLMQFD 1121

[Close]

BLAST of Calcium-activated potassium channel subunit alpha-1 vs. Ensembl Human
Match: KCNMA1 (potassium calcium-activated channel subfamily M alpha 1 [Source:HGNC Symbol;Acc:HGNC:6284])

HSP 1 Score: 348.591 bits (893), Expect = 6.343e-102
Identity = 276/979 (28.19%), Postives = 451/979 (46.07%), Query Frame = 2

Query:  323 IMISKSTIVGRFLNFVKLISQLTSWGIFVVFTFNQVNANYLIGDCFDVEGANLQWIDFALNIFCLFHFTLRAFAANDILKFWIQPTTMIEITVIPNILLTSFLPVRRQGFSFLRIYYLRELCNTIAVSFGILKVNSKFEMTKVIFYIISLWLISAGLFHMFEGIGNFWEIPLFNQQLSFWRCCYFMLVTISTVGFGSVNPLTIFGRIVVLVYIIYGITMFVTVLPNVIRTIQNLK-YKNRYISKGNERHIIVCGKFESLTIIAFLKAFKRERFKGSVRNVKIVTMNKDLYDENLLMYMKRFSNPIKYLIGNLSNRKDLKRVNIQKAKLSVILSTPFTNKISEDDIDNIMTAMILKSQRKNMRTIVQLHLYSNKVLLKMSPMWNQNRSDIILCIDELKLGLMAYNCLTPGIATLVINLVTFTKSKSVSE-LWRKDYENGLKVLLYNVQFSDCFHGMSCLEVALIVYKLWDVCLLAIKCVNKSTDDYVLINPMIENIKIDTDSMIAIVMARDEASSNKLIFYCSKC----SPQNQSEICQC----YLEATKNS---PRGHYESNLQFENQRINESFRSAYEFPTIDSKSEEID--INSYTGLDRTGSFYWAPEPNFEDVCLDIETAESRSLSDHILVCLCG-IGHGTIDLCNFMMPLRFQNLQNSELRTIVILGNKSYFEADKWTNIKNFPMFLIIDGSPIQSRDLRAAGLLKCHTCVIINGNDKTV---GFSDKSAIICATLIRSMRKLNKLKI---------------------PIMIEIRKDEIAH--HFSSIHSHNNDSKVS-------------VQHSEPFARGILFTNSTVYSCIYTVYKNPDTFSFIKTLLNGRYSDEIESMFGSGVGL-----LPQXXXXXXXXXXXXIIKLFSVIQPPLNEISRVYDGILDYACLFEWALMEKRILCLGLYRLNFGR--------NRYVFTHPEKSTEIFSTDQVYCCVSSD 3055
            +MIS  T+ GR L  V L+  L S G  V++  +  N    I  C +        ID A N+F L +F LR  AAND L FW++  ++++   +P + ++ +L     G  FLR   L +    +     ILK ++  ++  ++   IS WL +AG  H+ E  G+ WE    NQ L++W C Y ++VT+STVG+G V   T  GR+ ++ +I+ G+ MF + +P +I  I N K Y   Y +    +HI+VCG     ++  FLK F  +  +  V NV+IV ++    +  L    KR    +++  G++ N  DL RV I+ A   +IL+  +      +D  NIM  + +K+    +R I Q+  Y NK  L   P WN    D  +C+ ELKLG +A +CL  G++T++ NL +      + E  W+K Y  G+   +Y    S  F G+S   V  + +    + ++AI+  + + +  +LINP   ++KI  +  +   +A D     +  FYC  C    +   + + C C    Y E  + S   P+   + N    N   N S +     P +   +++ID   ++    D TG F+W      E V L    A    LS H++VC+ G +    I L N +MPLR  N    EL+ IV +G+  Y + + W  + NFP   I+ G+P+   DLRA  +  C  CVI++ N   +      DK  I+ +  I+SM+  + + +                     P+   +R+  I    +   I    ND+ V              +  ++PFA G  F  S + S +   Y N +  + I+TL+ G  + E+E++      L      PQ  ++ +R      +   +++  P  ++    DG   Y  LF  AL    +LC G+YRL             RYV T+P    E+  TD ++C +  D
Sbjct:  168 VMISAQTLTGRVL--VVLVFAL-SIGALVIYFIDSSNP---IESCQNFYKDFTLQIDMAFNVFFLLYFGLRFIAANDKLWFWLEVNSVVDFFTVPPVFVSVYLNRSWLGLRFLRALRLIQFSEILQF-LNILKTSNSIKLVNLLSIFISTWLTAAGFIHLVENSGDPWENFQNNQALTYWECVYLLMVTMSTVGYGDVYAKTTLGRLFMVFFILGGLAMFASYVPEIIELIGNRKKYGGSYSAVSGRKHIVVCGHITLESVSNFLKDFLHKD-RDDV-NVEIVFLHNISPNLELEALFKRHFTQVEFYQGSVLNPHDLARVKIESADACLILANKYCADPDAEDASNIMRVISIKNYHPKIRIITQMLQYHNKAHLLNIPSWNWKEGDDAICLAELKLGFIAQSCLAQGLSTMLANLFSMRSFIKIEEDTWQKYYLEGVSNEMYTEYLSSAFVGLSFPTVCELCFVKLKLLMIAIEYKSANRESRILINPG-NHLKIQ-EGTLGFFIASDAKEVKRAFFYCKACHDDITDPKRIKKCGCKRLIYFEDEQPSTLSPKKK-QRNGGMRNSP-NTSPKLMRHDPLLIPGNDQIDNMDSNVKKYDSTGMFHWCAPKEIEKVILTRSEAAMTVLSGHVVVCIFGDVSSALIGLRNLVMPLRASNFHYHELKHIVFVGSIEYLKRE-WETLHNFPKVSILPGTPLSRADLRAVNINLCDMCVILSANQNNIDDTSLQDKECILASLNIKSMQFDDSIGVLQANSQGFTPPGMDRSSPDNSPVHGMLRQPSITTGVNIPIITELVNDTNVQFLDQDDDDDPDTELYLTQPFACGTAFAVSVLDSLMSATYFNDNILTLIRTLVTGGATPELEALIAEENALRGGYSTPQTLANRDRCR----VAQLALLDGPFADLG---DGGC-YGDLFCKALKTYNMLCFGIYRLRDAHLSTPSQCTKRYVITNPPYEFELVPTDLIFCLMQFD 1124

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BLAST of Calcium-activated potassium channel subunit alpha-1 vs. Ensembl Celegans
Match: slo-1 (Calcium-activated potassium channel slo-1 [Source:UniProtKB/Swiss-Prot;Acc:Q95V25])

HSP 1 Score: 343.199 bits (879), Expect = 7.204e-101
Identity = 276/988 (27.94%), Postives = 449/988 (45.45%), Query Frame = 2

Query:  326 MISKSTIVGRFLNFVKLISQLTSWGIFVVFTFNQVNANYLIGDCFDVEGANLQWIDFALNIFCLFHFTLRAFAANDILKFWIQPTTMIEITVIPNILLTSFLPVRRQGFSFLRIYYLRELCNTIAVSFGILKVNSKFEMTKVIFYIISLWLISAGLFHMFEGIGNFWEIPLFNQQLSFWRCCYFMLVTISTVGFGSVNPLTIFGRIVVLVYIIYGITMFVTVLPNVIRTIQN-LKYKNRYISKGNERHIIVCGKFESLTIIAFLKAFKRERFKGSVRNVKIVTMNKDLYDENLLMYMKRFSNPIKYLIGNLSNRKDLKRVNIQKAKLSVILSTPFTNKISEDDIDNIMTAMILKSQRKNMRTIVQLHLYSNKVLLKMSPMWNQNRSDIILCIDELKLGLMAYNCLTPGIATLVINLVTFT--KSKSVSELWRKDYENGLKVLLYNVQFSDCFHGMSCLEVALIVYKLWDVCLLAIKCVNKSTDD-YVLINPMIENIKIDTDSMIAIVMARDEASSNKLIFYCSKC------------------------------SPQNQSEICQCYLEATKNSPRGHYESNLQFE--NQRINESF--RSAYEFPT----ID-SKSEEIDINSYTGLDRTGSFYWAPEPNFEDVCLDIETAESRSLSDHILVCLCGIGHGT-IDLCNFMMPLRFQNLQNSELRTIVILGNKSYFEADKWTNIKNFPMFLIIDGSPIQSRDLRAAGLLKCHTCVIING---NDKTVGFSDKSAIICATLIRSMR---------------KLNKLKIPIMIEIRKDEIAHHFSSIHSHNNDSKV-------------SVQHSEPFARGILFTNSTVYSCIYTVYKNPDTFSFIKTLLNGRYSDEIESMFGSGVGLLPQXXXXXXXXXXXXI-IKLFSVIQPPLNEISRVYDGILD---YACLFEWALMEKRILCLGLYRLNFGRN-----RYVFTHPEKSTEIFSTDQVY 3037
            +IS  ++ GRFL  +  I    S G  +++ ++    N+ +  C   + +  Q ID   NIF L +F +R  AA+D + F ++  + I+   IP   +  +L     GF FLR   L  + + +     ILK +S   +T+++   +++ L  AGL H+ E  G+F++  +   ++++    YF+LVT+STVG+G +   T+ GR+ ++ +I++G+ MF + +P +   I N  KY   Y  +  ++HI+VCG     ++  FL+ F  E        V    +++ + D  L    KR    +++  G + +  DL RV I  A   ++L+  ++     +D  NIM  + +K+   ++R IVQL  Y NK  L   P W+  R D ++C+ ELKLG +A +CL PG +T++ NL      K+   + LW  DY  G  + +Y    S  F  MS  E A +++    + LLAI+  ++   +  + INP    +         I  + DE    +  F+C +C                              +    +++ Q +       P GH    +Q    NQ+   S   R++   P     +D SK  E         D TG F+W P  N ED  L+   A    L+ H++VCL        I L NF+MPLR  N    EL+ +VI+G+  Y   + W  + N P   I++GSP+   DLRA  +  C  CVII+    N +    +DK AI+ +  I++M+                 + L  PI ++ +  +   +   I    NDS V              +  ++PFA G  F  S + S + T Y N    + I+TL+ G  + E+E +   G GL    S+ E   N +   I   S+   P       YDG++    Y  +F  AL     LC+GLYRL+   N     RYV T+P     I +TD VY
Sbjct:  130 LISGQSLTGRFLVLLVFI---LSIGSLIIYFYDASFQNFQVETCIPWQDSPSQQIDLGFNIFFLVYFFIRFIAASDKVWFLLEMYSWIDFFTIPPSFVAIYLQRNWLGFRFLRALRLMTVPDILQY-LNILKTSSSIRLTQLVTIFVAVCLTGAGLVHLLENSGDFFKGFINPHRITYADSVYFVLVTMSTVGYGDIYCTTLCGRLFMIFFILFGLAMFASYVPEIADLIGNRQKYGGEYKGEHGKKHIVVCGHITYDSVSHFLQDFLHEDRDDVDVEVVF--LHRVVPDLELEGLFKRHFTKVEFFTGTVMDSLDLSRVKIGDADACLVLANKYSTNPDAEDAANIMRVISIKNYSSDIRVIVQLMQYHNKAYLLNIPSWDWKRGDDVICLAELKLGFIAQSCLAPGFSTMMANLFAMRSFKTSPHTPLWLNDYLRGAGMEMYTESLSPSFANMSFPEAANLLFNRLGLLLLAIELKDEENKECNIAINPGPHIVIQPQTQGFFIAQSADEV--KRAFFWCKQCHDDIKDVSLIKKCKCKNLALFRRNTKHSTAARARATDVLQQFQPQAPAGPMGHLGQQVQLRMINQQRPSSGGRRNSMSIPPDGRGVDFSKDFEQQFQDMK-YDSTGMFHWCPSRNLEDCVLERHQAAMTVLNGHVVVCLFADQDSPLIGLRNFIMPLRSSNFHYHELKHVVIVGDLEYLRKE-WKTLYNLPKISILNGSPLSRADLRAVNINLCDMCVIISARVPNTEDTTLADKEAILASLNIKAMQFDDTLGFFPMRHQTGDRSPLGSPISMQKKGAKFGTNVPMITELVNDSNVQFLDQDDDDDPDTELYLTQPFACGTAFAISVLDSLMSTTYFNDSALTLIRTLVTGGATPELELILAEGAGLRGGYSTPETLSNRDRCRIAQISLQDNP-------YDGVVHNTTYGAMFTIALRRYGQLCIGLYRLHDQDNPDSMKRYVITNPPAELRIKNTDYVY 1100

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BLAST of Calcium-activated potassium channel subunit alpha-1 vs. Ensembl Celegans
Match: slo-1 (Calcium-activated potassium channel slo-1 [Source:UniProtKB/Swiss-Prot;Acc:Q95V25])

HSP 1 Score: 340.502 bits (872), Expect = 8.084e-100
Identity = 276/1009 (27.35%), Postives = 453/1009 (44.90%), Query Frame = 2

Query:  326 MISKSTIVGRFLNFVKLISQLTSWGIFVVFTFNQVNANYLIGDCFDVEGANLQWIDFALNIFCLFHFTLRAFAANDILKFWIQPTTMIEITVIPNILLTSFLPVRRQGFSFLRIYYLRELCNTIAVSFGILKVNSKFEMTKVIFYIISLWLISAGLFHMFEGIGNFWEIPLFNQQLSFWRCCYFMLVTISTVGFGSVNPLTIFGRIVVLVYIIYGITMFVTVLPNVIRTIQN-LKYKNRYISKGNERHIIVCGKFESLTIIAFLKAFKRERFKGSVRNVKIVTMNKDLYDENLLMYMKRFSNPIKYLIGNLSNRKDLKRVNIQKAKLSVILSTPFTNKISEDDIDNIMTAMILKSQRKNMRTIVQLHLYSNKVLLKMSPMWNQNRSDIILCIDELKLGLMAYNCLTPGIATLVINLVTFT--KSKSVSELWRKDYENGLKVLLYNVQFSDCFHGMSCLEVALIVYKLWDVCLLAIKCVNKSTDD-YVLINPMIENIKIDTDSMIAIVMARDEASSNKLIFYCSKC------------------------------SPQNQSEICQCYLEATKNSPRGHYESNLQFE--NQRIN--------ESFRSAYE----FPTIDSKSEEIDI--------------NSYTGL--DRTGSFYWAPEPNFEDVCLDIETAESRSLSDHILVCLCGIGHGT-IDLCNFMMPLRFQNLQNSELRTIVILGNKSYFEADKWTNIKNFPMFLIIDGSPIQSRDLRAAGLLKCHTCVIING---NDKTVGFSDKSAIICATLIRSMR---------------KLNKLKIPIMIEIRKDEIAHHFSSIHSHNNDSKVS-------------VQHSEPFARGILFTNSTVYSCIYTVYKNPDTFSFIKTLLNGRYSDEIESMFGSGVGLLPQXXXXXXXXXXXXI-IKLFSVIQPPLNEISRVYDGILD---YACLFEWALMEKRILCLGLYRLNFGRN-----RYVFTHPEKSTEIFSTDQVY 3037
            +IS  ++ GRFL  +  I    S G  +++ ++    N+ +  C   + +  Q ID   NIF L +F +R  AA+D + F ++  + I+   IP   +  +L     GF FLR   L  + + +     ILK +S   +T+++   +++ L  AGL H+ E  G+F++  +   ++++    YF+LVT+STVG+G +   T+ GR+ ++ +I++G+ MF + +P +   I N  KY   Y  +  ++HI+VCG     ++  FL+ F  E        V    +++ + D  L    KR    +++  G + +  DL RV I  A   ++L+  ++     +D  NIM  + +K+   ++R IVQL  Y NK  L   P W+  R D ++C+ ELKLG +A +CL PG +T++ NL      K+   + LW  DY  G  + +Y    S  F  MS  E A +++    + LLAI+  ++   +  + INP    +         I  + DE    +  F+C +C                              +    +++ Q +       P GH    +Q    NQ+ +        +S R AYE     P+   +   + I                +  +  D TG F+W P  N ED  L+   A    L+ H++VCL        I L NF+MPLR  N    EL+ +VI+G+  Y   + W  + N P   I++GSP+   DLRA  +  C  CVII+    N +    +DK AI+ +  I++M+                 + L  PI ++ +  +   +   I    NDS V              +  ++PFA G  F  S + S + T Y N    + I+TL+ G  + E+E +   G GL    S+ E   N +   I   S+   P       YDG++    Y  +F  AL     LC+GLYRL+   N     RYV T+P     I +TD VY
Sbjct:  130 LISGQSLTGRFLVLLVFI---LSIGSLIIYFYDASFQNFQVETCIPWQDSPSQQIDLGFNIFFLVYFFIRFIAASDKVWFLLEMYSWIDFFTIPPSFVAIYLQRNWLGFRFLRALRLMTVPDILQY-LNILKTSSSIRLTQLVTIFVAVCLTGAGLVHLLENSGDFFKGFINPHRITYADSVYFVLVTMSTVGYGDIYCTTLCGRLFMIFFILFGLAMFASYVPEIADLIGNRQKYGGEYKGEHGKKHIVVCGHITYDSVSHFLQDFLHEDRDDVDVEVVF--LHRVVPDLELEGLFKRHFTKVEFFTGTVMDSLDLSRVKIGDADACLVLANKYSTNPDAEDAANIMRVISIKNYSSDIRVIVQLMQYHNKAYLLNIPSWDWKRGDDVICLAELKLGFIAQSCLAPGFSTMMANLFAMRSFKTSPHTPLWLNDYLRGAGMEMYTESLSPSFANMSFPEAANLLFNRLGLLLLAIELKDEENKECNIAINPGPHIVIQPQTQGFFIAQSADEV--KRAFFWCKQCHDDIKDVSLIKKCKCKNLALFRRNTKHSTAARARATDVLQQFQPQAPAGPMGHLGQQVQLRMINQQSSTSDTHLNTKSLRFAYEIKKLMPSSGGRRNSMSIPPDGRGVDFSKDFEQQFQDMKYDSTGMFHWCPSRNLEDCVLERHQAAMTVLNGHVVVCLFADQDSPLIGLRNFIMPLRSSNFHYHELKHVVIVGDLEYLRKE-WKTLYNLPKISILNGSPLSRADLRAVNINLCDMCVIISARVPNTEDTTLADKEAILASLNIKAMQFDDTLGFFPMRHQTGDRSPLGSPISMQKKGAKFGTNVPMITELVNDSNVQFLDQDDDDDPDTELYLTQPFACGTAFAISVLDSLMSTTYFNDSALTLIRTLVTGGATPELELILAEGAGLRGGYSTPETLSNRDRCRIAQISLQDNP-------YDGVVHNTTYGAMFTIALRRYGQLCIGLYRLHDQDNPDSMKRYVITNPPAELRIKNTDYVY 1122

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BLAST of Calcium-activated potassium channel subunit alpha-1 vs. Ensembl Celegans
Match: slo-1 (Calcium-activated potassium channel slo-1 [Source:UniProtKB/Swiss-Prot;Acc:Q95V25])

HSP 1 Score: 337.806 bits (865), Expect = 8.780e-99
Identity = 278/1001 (27.77%), Postives = 450/1001 (44.96%), Query Frame = 2

Query:  326 MISKSTIVGRFLNFVKLISQLTSWGIFVVFTFNQVNANYLIGDCFDVEGANLQWIDFALNIFCLFHFTLRAFAANDILKFWIQPTTMIEITVIPNILLTSFLPVRRQGFSFLRIYYLRELCNTIAVSFGILKVNSKFEMTKVIFYIISLWLISAGLFHMFEGIGNFWEIPLFNQQLSFWRCCYFMLVTISTVGFGSVNPLTIFGRIVVLVYIIYGITMFVTVLPNVIRTIQN-LKYKNRYISKGNERHIIVCGKFESLTIIAFLKAFKRERFKGSVRNVKIVTMNKDLYDENLLMYMKRFSNPIKYLIGNLSNRKDLKRVNIQKAKLSVILSTPFTNKISEDDIDNIMTAMILKSQRKNMRTIVQLHLYSNKVLLKMSPMWNQNRSDIILCIDELKLGLMAYNCLTPGIATLVINLVTFT--KSKSVSELWRKDYENGLKVLLYNVQFSDCFHGMSCLEVALIVYKLWDVCLLAIKCVNKSTDD-YVLINPMIENIKIDTDSMIAIVMARDEASSNKLIFYCSKCSP----------------------------------------QNQS---EICQCYLEATKNSPRGHYESNLQFE--NQRINESF--RSAYEFPT----ID-SKSEEIDINSYTGLDRTGSFYWAPEPNFEDVCLDIETAESRSLSDHILVCLCGIGHGT-IDLCNFMMPLRFQNLQNSELRTIVILGNKSYFEADKWTNIKNFPMFLIIDGSPIQSRDLRAAGLLKCHTCVIING---NDKTVGFSDKSAIICATLIRSMR---------------KLNKLKIPIMIEIRKDEIAHHFSSIHSHNNDSKV-------------SVQHSEPFARGILFTNSTVYSCIYTVYKNPDTFSFIKTLLNGRYSDEIESMFGSGVGLLPQXXXXXXXXXXXXI-IKLFSVIQPPLNEISRVYDGILD---YACLFEWALMEKRILCLGLYRLNFGRN-----RYVFTHPEKSTEIFSTDQVY 3037
            +IS  ++ GRFL  +  I    S G  +++ ++    N+ +  C   + +  Q ID   NIF L +F +R  AA+D + F ++  + I+   IP   +  +L     GF FLR   L  + + +     ILK +S   +T+++   +++ L  AGL H+ E  G+F++  +   ++++    YF+LVT+STVG+G +   T+ GR+ ++ +I++G+ MF + +P +   I N  KY   Y  +  ++HI+VCG     ++  FL+ F  E        V    +++ + D  L    KR    +++  G + +  DL RV I  A   ++L+  ++     +D  NIM  + +K+   ++R IVQL  Y NK  L   P W+  R D ++C+ ELKLG +A +CL PG +T++ NL      K+   + LW  DY  G  + +Y    S  F  MS  E A +++    + LLAI+  ++   +  + INP    +         I  + DE    +  F+C +C                                          QN +   ++ Q +       P GH    +Q    NQ+   S   R++   P     +D SK  E         D TG F+W P  N ED  L+   A    L+ H++VCL        I L NF+MPLR  N    EL+ +VI+G+  Y   + W  + N P   I++GSP+   DLRA  +  C  CVII+    N +    +DK AI+ +  I++M+                 + L  PI ++ +  +   +   I    NDS V              +  ++PFA G  F  S + S + T Y N    + I+TL+ G  + E+E +   G GL    S+ E   N +   I   S+   P       YDG++    Y  +F  AL     LC+GLYRL+   N     RYV T+P     I +TD VY
Sbjct:  130 LISGQSLTGRFLVLLVFI---LSIGSLIIYFYDASFQNFQVETCIPWQDSPSQQIDLGFNIFFLVYFFIRFIAASDKVWFLLEMYSWIDFFTIPPSFVAIYLQRNWLGFRFLRALRLMTVPDILQY-LNILKTSSSIRLTQLVTIFVAVCLTGAGLVHLLENSGDFFKGFINPHRITYADSVYFVLVTMSTVGYGDIYCTTLCGRLFMIFFILFGLAMFASYVPEIADLIGNRQKYGGEYKGEHGKKHIVVCGHITYDSVSHFLQDFLHEDRDDVDVEVVF--LHRVVPDLELEGLFKRHFTKVEFFTGTVMDSLDLSRVKIGDADACLVLANKYSTNPDAEDAANIMRVISIKNYSSDIRVIVQLMQYHNKAYLLNIPSWDWKRGDDVICLAELKLGFIAQSCLAPGFSTMMANLFAMRSFKTSPHTPLWLNDYLRGAGMEMYTESLSPSFANMSFPEAANLLFNRLGLLLLAIELKDEENKECNIAINPGPHIVIQPQTQGFFIAQSADEV--KRAFFWCKQCHDDIKDVSLIKKCKCKNLALFRRNTKHSTAARDYSDFDALFYQNDARATDVLQQFQPQAPAGPMGHLGQQVQLRMINQQRPSSGGRRNSMSIPPDGRGVDFSKDFEQQFQDMK-YDSTGMFHWCPSRNLEDCVLERHQAAMTVLNGHVVVCLFADQDSPLIGLRNFIMPLRSSNFHYHELKHVVIVGDLEYLRKE-WKTLYNLPKISILNGSPLSRADLRAVNINLCDMCVIISARVPNTEDTTLADKEAILASLNIKAMQFDDTLGFFPMRHQTGDRSPLGSPISMQKKGAKFGTNVPMITELVNDSNVQFLDQDDDDDPDTELYLTQPFACGTAFAISVLDSLMSTTYFNDSALTLIRTLVTGGATPELELILAEGAGLRGGYSTPETLSNRDRCRIAQISLQDNP-------YDGVVHNTTYGAMFTIALRRYGQLCIGLYRLHDQDNPDSMKRYVITNPPAELRIKNTDYVY 1113

[Close]

BLAST of Calcium-activated potassium channel subunit alpha-1 vs. Ensembl Celegans
Match: slo-1 (Calcium-activated potassium channel slo-1 [Source:UniProtKB/Swiss-Prot;Acc:Q95V25])

HSP 1 Score: 335.88 bits (860), Expect = 4.846e-98
Identity = 278/1022 (27.20%), Postives = 454/1022 (44.42%), Query Frame = 2

Query:  326 MISKSTIVGRFLNFVKLISQLTSWGIFVVFTFNQVNANYLIGDCFDVEGANLQWIDFALNIFCLFHFTLRAFAANDILKFWIQPTTMIEITVIPNILLTSFLPVRRQGFSFLRIYYLRELCNTIAVSFGILKVNSKFEMTKVIFYIISLWLISAGLFHMFEGIGNFWEIPLFNQQLSFWRCCYFMLVTISTVGFGSVNPLTIFGRIVVLVYIIYGITMFVTVLPNVIRTIQN-LKYKNRYISKGNERHIIVCGKFESLTIIAFLKAFKRERFKGSVRNVKIVTMNKDLYDENLLMYMKRFSNPIKYLIGNLSNRKDLKRVNIQKAKLSVILSTPFTNKISEDDIDNIMTAMILKSQRKNMRTIVQLHLYSNKVLLKMSPMWNQNRSDIILCIDELKLGLMAYNCLTPGIATLVINLVTFT--KSKSVSELWRKDYENGLKVLLYNVQFSDCFHGMSCLEVALIVYKLWDVCLLAIKCVNKSTDD-YVLINPMIENIKIDTDSMIAIVMARDEASSNKLIFYCSKCSP----------------------------------------QNQS---EICQCYLEATKNSPRGHYESNLQFE--NQRIN--------ESFRSAYE----FPTIDSKSEEIDI--------------NSYTGL--DRTGSFYWAPEPNFEDVCLDIETAESRSLSDHILVCLCGIGHGT-IDLCNFMMPLRFQNLQNSELRTIVILGNKSYFEADKWTNIKNFPMFLIIDGSPIQSRDLRAAGLLKCHTCVIING---NDKTVGFSDKSAIICATLIRSMR---------------KLNKLKIPIMIEIRKDEIAHHFSSIHSHNNDSKVS-------------VQHSEPFARGILFTNSTVYSCIYTVYKNPDTFSFIKTLLNGRYSDEIESMFGSGVGLLPQXXXXXXXXXXXXI-IKLFSVIQPPLNEISRVYDGILD---YACLFEWALMEKRILCLGLYRLNFGRN-----RYVFTHPEKSTEIFSTDQVY 3037
            +IS  ++ GRFL  +  I    S G  +++ ++    N+ +  C   + +  Q ID   NIF L +F +R  AA+D + F ++  + I+   IP   +  +L     GF FLR   L  + + +     ILK +S   +T+++   +++ L  AGL H+ E  G+F++  +   ++++    YF+LVT+STVG+G +   T+ GR+ ++ +I++G+ MF + +P +   I N  KY   Y  +  ++HI+VCG     ++  FL+ F  E        V    +++ + D  L    KR    +++  G + +  DL RV I  A   ++L+  ++     +D  NIM  + +K+   ++R IVQL  Y NK  L   P W+  R D ++C+ ELKLG +A +CL PG +T++ NL      K+   + LW  DY  G  + +Y    S  F  MS  E A +++    + LLAI+  ++   +  + INP    +         I  + DE    +  F+C +C                                          QN +   ++ Q +       P GH    +Q    NQ+ +        +S R AYE     P+   +   + I                +  +  D TG F+W P  N ED  L+   A    L+ H++VCL        I L NF+MPLR  N    EL+ +VI+G+  Y   + W  + N P   I++GSP+   DLRA  +  C  CVII+    N +    +DK AI+ +  I++M+                 + L  PI ++ +  +   +   I    NDS V              +  ++PFA G  F  S + S + T Y N    + I+TL+ G  + E+E +   G GL    S+ E   N +   I   S+   P       YDG++    Y  +F  AL     LC+GLYRL+   N     RYV T+P     I +TD VY
Sbjct:  130 LISGQSLTGRFLVLLVFI---LSIGSLIIYFYDASFQNFQVETCIPWQDSPSQQIDLGFNIFFLVYFFIRFIAASDKVWFLLEMYSWIDFFTIPPSFVAIYLQRNWLGFRFLRALRLMTVPDILQY-LNILKTSSSIRLTQLVTIFVAVCLTGAGLVHLLENSGDFFKGFINPHRITYADSVYFVLVTMSTVGYGDIYCTTLCGRLFMIFFILFGLAMFASYVPEIADLIGNRQKYGGEYKGEHGKKHIVVCGHITYDSVSHFLQDFLHEDRDDVDVEVVF--LHRVVPDLELEGLFKRHFTKVEFFTGTVMDSLDLSRVKIGDADACLVLANKYSTNPDAEDAANIMRVISIKNYSSDIRVIVQLMQYHNKAYLLNIPSWDWKRGDDVICLAELKLGFIAQSCLAPGFSTMMANLFAMRSFKTSPHTPLWLNDYLRGAGMEMYTESLSPSFANMSFPEAANLLFNRLGLLLLAIELKDEENKECNIAINPGPHIVIQPQTQGFFIAQSADEV--KRAFFWCKQCHDDIKDVSLIKKCKCKNLALFRRNTKHSTAARDYSDFDALFYQNDARATDVLQQFQPQAPAGPMGHLGQQVQLRMINQQSSTSDTHLNTKSLRFAYEIKKLMPSSGGRRNSMSIPPDGRGVDFSKDFEQQFQDMKYDSTGMFHWCPSRNLEDCVLERHQAAMTVLNGHVVVCLFADQDSPLIGLRNFIMPLRSSNFHYHELKHVVIVGDLEYLRKE-WKTLYNLPKISILNGSPLSRADLRAVNINLCDMCVIISARVPNTEDTTLADKEAILASLNIKAMQFDDTLGFFPMRHQTGDRSPLGSPISMQKKGAKFGTNVPMITELVNDSNVQFLDQDDDDDPDTELYLTQPFACGTAFAISVLDSLMSTTYFNDSALTLIRTLVTGGATPELELILAEGAGLRGGYSTPETLSNRDRCRIAQISLQDNP-------YDGVVHNTTYGAMFTIALRRYGQLCIGLYRLHDQDNPDSMKRYVITNPPAELRIKNTDYVY 1135

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BLAST of Calcium-activated potassium channel subunit alpha-1 vs. Ensembl Celegans
Match: slo-1 (Calcium-activated potassium channel slo-1 [Source:UniProtKB/Swiss-Prot;Acc:Q95V25])

HSP 1 Score: 335.495 bits (859), Expect = 6.085e-98
Identity = 278/1008 (27.58%), Postives = 450/1008 (44.64%), Query Frame = 2

Query:  326 MISKSTIVGRFLNFVKLISQLTSWGIFVVFTFNQVNANYLIGDCFDVEGANLQWIDFALNIFCLFHFTLRAFAANDILKFWIQPTTMIEITVIPNILLTSFLPVRRQGFSFLRIYYLRELCNTIAVSFGILKVNSKFEMTKVIFYIISLWLISAGLFHMFEGIGNFWEIPLFNQQLSFWRCCYFMLVTISTVGFGSVNPLTIFGRIVVLVYIIYGITMFVTVLPNVIRTIQN-LKYKNRYISKGNERHIIVCGKFESLTIIAFLKAFKRERFKGSVRNVKIVTMNKDLYDENLLMYMKRFSNPIKYLIGNLSNRKDLKRVNIQKAKLSVILSTPFTNKISEDDIDNIMTAMILKSQRKNMRTIVQLHLYSNKVLLKMSPMWNQNRSDIILCIDELKLGLMAYNCLTPGIATLVINLVTFT--KSKSVSELWRKDYENGLKVLLYNVQFSDCFHGMSCLEVALIVYKLWDVCLLAIKCVNKSTDD-YVLINPMIENIKIDTDSMIAIVMARDEASSNKLIFYCSKCSP-----------------------------------------------QNQS---EICQCYLEATKNSPRGHYESNLQFE--NQRINESF--RSAYEFPT----ID-SKSEEIDINSYTGLDRTGSFYWAPEPNFEDVCLDIETAESRSLSDHILVCLCGIGHGT-IDLCNFMMPLRFQNLQNSELRTIVILGNKSYFEADKWTNIKNFPMFLIIDGSPIQSRDLRAAGLLKCHTCVIING---NDKTVGFSDKSAIICATLIRSMR---------------KLNKLKIPIMIEIRKDEIAHHFSSIHSHNNDSKV-------------SVQHSEPFARGILFTNSTVYSCIYTVYKNPDTFSFIKTLLNGRYSDEIESMFGSGVGLLPQXXXXXXXXXXXXI-IKLFSVIQPPLNEISRVYDGILD---YACLFEWALMEKRILCLGLYRLNFGRN-----RYVFTHPEKSTEIFSTDQVY 3037
            +IS  ++ GRFL  +  I    S G  +++ ++    N+ +  C   + +  Q ID   NIF L +F +R  AA+D + F ++  + I+   IP   +  +L     GF FLR   L  + + +     ILK +S   +T+++   +++ L  AGL H+ E  G+F++  +   ++++    YF+LVT+STVG+G +   T+ GR+ ++ +I++G+ MF + +P +   I N  KY   Y  +  ++HI+VCG     ++  FL+ F  E        V    +++ + D  L    KR    +++  G + +  DL RV I  A   ++L+  ++     +D  NIM  + +K+   ++R IVQL  Y NK  L   P W+  R D ++C+ ELKLG +A +CL PG +T++ NL      K+   + LW  DY  G  + +Y    S  F  MS  E A +++    + LLAI+  ++   +  + INP    +         I  + DE    +  F+C +C                                                 QN +   ++ Q +       P GH    +Q    NQ+   S   R++   P     +D SK  E         D TG F+W P  N ED  L+   A    L+ H++VCL        I L NF+MPLR  N    EL+ +VI+G+  Y   + W  + N P   I++GSP+   DLRA  +  C  CVII+    N +    +DK AI+ +  I++M+                 + L  PI ++ +  +   +   I    NDS V              +  ++PFA G  F  S + S + T Y N    + I+TL+ G  + E+E +   G GL    S+ E   N +   I   S+   P       YDG++    Y  +F  AL     LC+GLYRL+   N     RYV T+P     I +TD VY
Sbjct:  130 LISGQSLTGRFLVLLVFI---LSIGSLIIYFYDASFQNFQVETCIPWQDSPSQQIDLGFNIFFLVYFFIRFIAASDKVWFLLEMYSWIDFFTIPPSFVAIYLQRNWLGFRFLRALRLMTVPDILQY-LNILKTSSSIRLTQLVTIFVAVCLTGAGLVHLLENSGDFFKGFINPHRITYADSVYFVLVTMSTVGYGDIYCTTLCGRLFMIFFILFGLAMFASYVPEIADLIGNRQKYGGEYKGEHGKKHIVVCGHITYDSVSHFLQDFLHEDRDDVDVEVVF--LHRVVPDLELEGLFKRHFTKVEFFTGTVMDSLDLSRVKIGDADACLVLANKYSTNPDAEDAANIMRVISIKNYSSDIRVIVQLMQYHNKAYLLNIPSWDWKRGDDVICLAELKLGFIAQSCLAPGFSTMMANLFAMRSFKTSPHTPLWLNDYLRGAGMEMYTESLSPSFANMSFPEAANLLFNRLGLLLLAIELKDEENKECNIAINPGPHIVIQPQTQGFFIAQSADEV--KRAFFWCKQCHDDIKDVSLIKKCKCKNLALFRRNTKHSTAAREKNAKISDYSDFDALFYQNDARATDVLQQFQPQAPAGPMGHLGQQVQLRMINQQRPSSGGRRNSMSIPPDGRGVDFSKDFEQQFQDMK-YDSTGMFHWCPSRNLEDCVLERHQAAMTVLNGHVVVCLFADQDSPLIGLRNFIMPLRSSNFHYHELKHVVIVGDLEYLRKE-WKTLYNLPKISILNGSPLSRADLRAVNINLCDMCVIISARVPNTEDTTLADKEAILASLNIKAMQFDDTLGFFPMRHQTGDRSPLGSPISMQKKGAKFGTNVPMITELVNDSNVQFLDQDDDDDPDTELYLTQPFACGTAFAISVLDSLMSTTYFNDSALTLIRTLVTGGATPELELILAEGAGLRGGYSTPETLSNRDRCRIAQISLQDNP-------YDGVVHNTTYGAMFTIALRRYGQLCIGLYRLHDQDNPDSMKRYVITNPPAELRIKNTDYVY 1120

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BLAST of Calcium-activated potassium channel subunit alpha-1 vs. Ensembl Fly
Match: slo (gene:FBgn0003429 transcript:FBtr0334294)

HSP 1 Score: 344.739 bits (883), Expect = 3.784e-101
Identity = 280/1028 (27.24%), Postives = 459/1028 (44.65%), Query Frame = 2

Query:  326 MISKSTIVGRFLNFVKLISQLTSWGIFVVFTFNQVNANYLIGDCFDVEGANLQWIDFALNIFCLFHFTLRAFAANDILKFWIQPTTMIEITVIPNILLTSFLPVRRQGFSFLRIYYLRELCNTIAVSFGILKVNSKFEMTKVIFYIISLWLISAGLFHMFEGIGNFWEIPL-FN--QQLSFWRCCYFMLVTISTVGFGSVNPLTIFGRIVVLVYIIYGITMFVTVLPNVIRTIQNL-KYKNRYISKGNERHIIVCGKFESLTIIAFLKAFKRERFKGSVRNVKIVTMNKDLYDENLLMYMKRFSNPIKYLIGNLSNRKDLKRVNIQKAKLSVILSTPFTNKISEDDIDNIMTAMILKSQRKNMRTIVQLHLYSNKVLLKMSPMWNQNRSDIILCIDELKLGLMAYNCLTPGIATLVINLVTFT--KSKSVSELWRKDYENGLKVLLYNVQFSDCFHGMSCLEVALIVYKLWDVCLLA--IKCVNKSTDDYVLINPMIENIKIDTDSMIAIVMARDEASSNKLIFYCSKCSPQNQSEI----CQCYLEATKNSPRG----------HYESNL-------------------------QFENQRINESFRSAYEFPT---------------------IDSKSEEIDIN-SYTGLDRTGSFYWAPEPNFEDVCLDIETAESRSLSDHILVCL-CGIGHGTIDLCNFMMPLRFQNLQNSELRTIVILGNKSYFEADKWTNIKNFPMFLIIDGSPIQSRDLRAAGLLKCHTCVIING----NDKTVGFSDKSAIICATLIRSMRKLNKLKI-----------------PIMIEIRKDEIAHHFSSIHSHNNDSKV-------------SVQHSEPFARGILFTNSTVYSCIYTVYKNPDTFSFIKTLLNGRYSDEIESMFGSGVGLLPQXXXXXXXXXXXXIIKLFSVIQPPLNEISRVYDGIL-------DYACLFEWALMEKRILCLGLYRL-------NFGRNRYVFTHPEKSTEIFSTDQVYCCVSSD 3055
            +IS  T  GR L  +  I  + S  I+ V   ++      +  C        Q ID A NIF + +F +R  AA+D L F ++  + ++   IP   ++ +L     G  FLR   L  + + +     +LK +S   + +++   IS+WL +AG+ H+ E  G+    PL FN   +LS+W C YF++VT+STVG+G V   T+ GR  ++ +++ G+ MF + +P +I  + +  KY      +  +RHI+VCG     ++  FLK F  E  +    +V++V +++   D  L    KR    +++  G + N  DL+RV + +A   ++L+  +      +D  NIM  + +K+   ++R I+QL  Y NK  L   P W+  + D ++C+ ELKLG +A +CL PG +T++ NL      K+   ++ W+ DY  G    +Y    S  F GM+  + + + +    + LLA  IK   +  D  + INP    I+ +T     I  + DE    +  FYC  C    + E     C+C     +N  R           H+ +N                          Q E Q I+    S Y  PT                      D +S++ D   +    D TG F+W+P  + ED  LD   A    L+ H++VCL        I L N +MPLR  N    EL+ +VI+G+  Y   + W  ++N P   +++GSP+   DLRA  +  C  C I++     ND     +DK AI+ +  I++M   + + +                 PI+++ R      +   I    NDS V              +  ++PFA G  F  S + S + T Y N +  + I++L+ G  + E+E +   G GL         R   +++  L +  +  + +IS +YDG L        Y  LF  AL    +LC+GLYR        +    RYV T+P     +  TDQV+  +  D
Sbjct:  101 LISGQTTTGRILVVLVFILSIASLIIYFVDASSEE-----VERCQKWSNNITQQIDLAFNIFFMVYFFIRFIAASDKLWFMLEMYSFVDYFTIPPSFVSIYLDRTWIGLRFLRALRLMTVPDILQY-LNVLKTSSSIRLAQLVSIFISVWLTAAGIIHLLENSGD----PLDFNNAHRLSYWTCVYFLIVTMSTVGYGDVYCETVLGRTFLVFFLLVGLAMFASSIPEIIELVGSGNKYGGELKREHGKRHIVVCGHITYESVSHFLKDFLHEDREDV--DVEVVFLHRKPPDLELEGLFKRHFTTVEFFQGTIMNPIDLQRVKVHEADACLVLANKYCQDPDAEDAANIMRVISIKNYSDDIRVIIQLMQYHNKAYLLNIPSWDWKQGDDVICLAELKLGFIAQSCLAPGFSTMMANLFAMRSFKTSPDTQAWQNDYLQGTGCEMYTETLSPSFTGMTFPQASELCFSKLKLLLLAIEIKGAEEGADSKISINPRGAKIQANTQGFF-IAQSADEV--KRAWFYCKACHEDIKDETLIKKCKCKNLLNRNVRRPNGTGNGTGGMHHMNNTAAAAAAAAAAGKQVNKVKPTVNVSRQVEGQVISP---SQYNRPTSRSSGTGTQNQNGGVSLPAGIADDQSKDFDFEKTEMKYDSTGMFHWSPAKSLEDCILDRNQAAMTVLNGHVVVCLFADPDSPLIGLRNLVMPLRASNFHYHELKHVVIVGSVDYIRRE-WKMLQNLPKISVLNGSPLSRADLRAVNVNLCDMCCILSAKVPSNDDPT-LADKEAILASLNIKAMTFDDTIGVLSQRGPEFDNLSATAGSPIVLQRRGSVYGANVPMITELVNDSNVQFLDQDDDDDPDTELYLTQPFACGTAFAVSVLDSLMSTTYFNQNALTLIRSLITGGATPELELILAEGAGL---------RGGYSTVESLSNRDRCRVGQIS-LYDGPLAQFGECGKYGDLFVAALKSYGMLCIGLYRFRDTSSSCDASSKRYVITNPPDDFSLLPTDQVFVLMQFD 1098

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BLAST of Calcium-activated potassium channel subunit alpha-1 vs. Ensembl Fly
Match: slo (gene:FBgn0003429 transcript:FBtr0100636)

HSP 1 Score: 241.506 bits (615), Expect = 2.051e-65
Identity = 160/556 (28.78%), Postives = 276/556 (49.64%), Query Frame = 2

Query:  326 MISKSTIVGRFLNFVKLISQLTSWGIFVVFTFNQVNANYLIGDCFDVEGANLQWIDFALNIFCLFHFTLRAFAANDILKFWIQPTTMIEITVIPNILLTSFLPVRRQGFSFLRIYYLRELCNTIAVSFGILKVNSKFEMTKVIFYIISLWLISAGLFHMFEGIGNFWEIPL-FN--QQLSFWRCCYFMLVTISTVGFGSVNPLTIFGRIVVLVYIIYGITMFVTVLPNVIRTIQNL-KYKNRYISKGNERHIIVCGKFESLTIIAFLKAFKRERFKGSVRNVKIVTMNKDLYDENLLMYMKRFSNPIKYLIGNLSNRKDLKRVNIQKAKLSVILSTPFTNKISEDDIDNIMTAMILKSQRKNMRTIVQLHLYSNKVLLKMSPMWNQNRSDIILCIDELKLGLMAYNCLTPGIATLVINLVTFT--KSKSVSELWRKDYENGLKVLLYNVQFSDCFHGMSCLEVALIVYKLWDVCLLA--IKCVNKSTDDYVLINPMIENIKIDTDSMIAIVMARDEASSNKLIFYCSKCSP--QNQSEICQCYLEATKNSPRGHYE 1963
            +IS  T  GR L  +  I  + S  I+ V   ++      +  C        Q ID A NIF + +F +R  AA+D L F ++  + ++   IP   ++ +L     G  FLR   L  + + +     +LK +S   + +++   IS+WL +AG+ H+ E  G+    PL FN   +LS+W C YF++VT+STVG+G V   T+ GR  ++ +++ G+ MF + +P +I  + +  KY      +  +RHI+VCG     ++  FLK F  E  +    +V++V +++   D  L    KR    +++  G + N  DL+RV + +A   ++L+  +      +D  NIM  + +K+   ++R I+QL  Y NK  L   P W+  + D ++C+ ELKLG +A +CL PG +T++ NL      K+   ++ W+ DY  G    +Y    S  F GM+  + + + +    + LLA  IK   +  D  + INP    I+ +T     I  + DE    +  FYC  C    ++++ I +C  +     PR  ++
Sbjct:  118 LISGQTTTGRILVVLVFILSIASLIIYFVDASSEE-----VERCQKWSNNITQQIDLAFNIFFMVYFFIRFIAASDKLWFMLEMYSFVDYFTIPPSFVSIYLDRTWIGLRFLRALRLMTVPDILQY-LNVLKTSSSIRLAQLVSIFISVWLTAAGIIHLLENSGD----PLDFNNAHRLSYWTCVYFLIVTMSTVGYGDVYCETVLGRTFLVFFLLVGLAMFASSIPEIIELVGSGNKYGGELKREHGKRHIVVCGHITYESVSHFLKDFLHEDREDV--DVEVVFLHRKPPDLELEGLFKRHFTTVEFFQGTIMNPIDLQRVKVHEADACLVLANKYCQDPDAEDAANIMRVISIKNYSDDIRVIIQLMQYHNKAYLLNIPSWDWKQGDDVICLAELKLGFIAQSCLAPGFSTMMANLFAMRSFKTSPDTQAWQNDYLQGTGCEMYTETLSPSFTGMTFPQASELCFSKLKLLLLAIEIKGAEEGADSKISINPRGAKIQANTQGFF-IAQSADEV--KRAWFYCKACHEDIKDETLIKKCKCKNLTVQPRSKFD 658

HSP 2 Score: 130.954 bits (328), Expect = 2.216e-30
Identity = 109/391 (27.88%), Postives = 174/391 (44.50%), Query Frame = 2

Query: 2033 DSKSEEIDIN-SYTGLDRTGSFYWAPEPNFEDVCLDIETAESRSLSDHILVCL-CGIGHGTIDLCNFMMPLRFQNLQNSELRTIVILGNKSYFEADKWTNIKNFPMFLIIDGSPIQSRDLRAAGLLKCHTCVIING----NDKTVGFSDKSAIICATLIRSMRKLNKLKI-----------------PIMIEIRKDEIAHHFSSIHSHNNDSKVS-------------VQHSEPFARGILFTNSTVYSCIYTVYKNPDTFSFIKTLLNGRYSDEIESMFGSGVGLLPQXXXXXXXXXXXXIIKLFSVIQPPLNEISRVYDGIL-------DYACLFEWALMEKRILCLGLYRL-------NFGRNRYVFTHPEKSTEIFSTDQVYCCVSSD 3055
            D +S++ D   +    D TG F+W+P  + ED  LD   A    L+ H++VCL        I L N +MPLR  N    EL+ +VI+G+  Y   + W  ++N P   +++GSP+   DLRA  +  C  C I++     ND     +DK AI+ +  I++M   + + +                 PI+++ R      +   I    NDS V              +  ++PFA G  F  S + S + T Y N +  + I++L+ G  + E+E +   G GL         R   +++  L +  +  + +IS +YDG L        Y  LF  AL    +LC+GLYR        +    RYV T+P     +  TDQV+  +  D
Sbjct:  749 DDQSKDFDFEKTEMKYDSTGMFHWSPAKSLEDCILDRNQAAMTVLNGHVVVCLFADPDSPLIGLRNLVMPLRASNFHYHELKHVVIVGSVDYIRRE-WKMLQNLPKISVLNGSPLSRADLRAVNVNLCDMCCILSAKVPSNDDPT-LADKEAILASLNIKAMTFDDTIGVLSQRGPEFDNLSATAGSPIVLQRRGSVYGANVPMITELVNDSNVQFLDQDDDDDPDTELYLTQPFACGTAFAVSVLDSLMSTTYFNQNALTLIRSLITGGATPELELILAEGAGL---------RGGYSTVESLSNRDRCRVGQIS-LYDGPLAQFGECGKYGDLFVAALKSYGMLCIGLYRFRDTSSSCDASSKRYVITNPPDDFSLLPTDQVFVLMQFD 1127

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BLAST of Calcium-activated potassium channel subunit alpha-1 vs. Ensembl Fly
Match: slo (gene:FBgn0003429 transcript:FBtr0084685)

HSP 1 Score: 241.121 bits (614), Expect = 2.748e-65
Identity = 160/556 (28.78%), Postives = 276/556 (49.64%), Query Frame = 2

Query:  326 MISKSTIVGRFLNFVKLISQLTSWGIFVVFTFNQVNANYLIGDCFDVEGANLQWIDFALNIFCLFHFTLRAFAANDILKFWIQPTTMIEITVIPNILLTSFLPVRRQGFSFLRIYYLRELCNTIAVSFGILKVNSKFEMTKVIFYIISLWLISAGLFHMFEGIGNFWEIPL-FN--QQLSFWRCCYFMLVTISTVGFGSVNPLTIFGRIVVLVYIIYGITMFVTVLPNVIRTIQNL-KYKNRYISKGNERHIIVCGKFESLTIIAFLKAFKRERFKGSVRNVKIVTMNKDLYDENLLMYMKRFSNPIKYLIGNLSNRKDLKRVNIQKAKLSVILSTPFTNKISEDDIDNIMTAMILKSQRKNMRTIVQLHLYSNKVLLKMSPMWNQNRSDIILCIDELKLGLMAYNCLTPGIATLVINLVTFT--KSKSVSELWRKDYENGLKVLLYNVQFSDCFHGMSCLEVALIVYKLWDVCLLA--IKCVNKSTDDYVLINPMIENIKIDTDSMIAIVMARDEASSNKLIFYCSKCSP--QNQSEICQCYLEATKNSPRGHYE 1963
            +IS  T  GR L  +  I  + S  I+ V   ++      +  C        Q ID A NIF + +F +R  AA+D L F ++  + ++   IP   ++ +L     G  FLR   L  + + +     +LK +S   + +++   IS+WL +AG+ H+ E  G+    PL FN   +LS+W C YF++VT+STVG+G V   T+ GR  ++ +++ G+ MF + +P +I  + +  KY      +  +RHI+VCG     ++  FLK F  E  +    +V++V +++   D  L    KR    +++  G + N  DL+RV + +A   ++L+  +      +D  NIM  + +K+   ++R I+QL  Y NK  L   P W+  + D ++C+ ELKLG +A +CL PG +T++ NL      K+   ++ W+ DY  G    +Y    S  F GM+  + + + +    + LLA  IK   +  D  + INP    I+ +T     I  + DE    +  FYC  C    ++++ I +C  +     PR  ++
Sbjct:  101 LISGQTTTGRILVVLVFILSIASLIIYFVDASSEE-----VERCQKWSNNITQQIDLAFNIFFMVYFFIRFIAASDKLWFMLEMYSFVDYFTIPPSFVSIYLDRTWIGLRFLRALRLMTVPDILQY-LNVLKTSSSIRLAQLVSIFISVWLTAAGIIHLLENSGD----PLDFNNAHRLSYWTCVYFLIVTMSTVGYGDVYCETVLGRTFLVFFLLVGLAMFASSIPEIIELVGSGNKYGGELKREHGKRHIVVCGHITYESVSHFLKDFLHEDREDV--DVEVVFLHRKPPDLELEGLFKRHFTTVEFFQGTIMNPIDLQRVKVHEADACLVLANKYCQDPDAEDAANIMRVISIKNYSDDIRVIIQLMQYHNKAYLLNIPSWDWKQGDDVICLAELKLGFIAQSCLAPGFSTMMANLFAMRSFKTSPDTQAWQNDYLQGTGCEMYTETLSPSFTGMTFPQASELCFSKLKLLLLAIEIKGAEEGADSKISINPRGAKIQANTQGFF-IAQSADEV--KRAWFYCKACHEDIKDETLIKKCKCKNLTVQPRSKFD 641

HSP 2 Score: 130.183 bits (326), Expect = 3.793e-30
Identity = 109/391 (27.88%), Postives = 174/391 (44.50%), Query Frame = 2

Query: 2033 DSKSEEIDIN-SYTGLDRTGSFYWAPEPNFEDVCLDIETAESRSLSDHILVCL-CGIGHGTIDLCNFMMPLRFQNLQNSELRTIVILGNKSYFEADKWTNIKNFPMFLIIDGSPIQSRDLRAAGLLKCHTCVIING----NDKTVGFSDKSAIICATLIRSMRKLNKLKI-----------------PIMIEIRKDEIAHHFSSIHSHNNDSKVS-------------VQHSEPFARGILFTNSTVYSCIYTVYKNPDTFSFIKTLLNGRYSDEIESMFGSGVGLLPQXXXXXXXXXXXXIIKLFSVIQPPLNEISRVYDGIL-------DYACLFEWALMEKRILCLGLYRL-------NFGRNRYVFTHPEKSTEIFSTDQVYCCVSSD 3055
            D +S++ D   +    D TG F+W+P  + ED  LD   A    L+ H++VCL        I L N +MPLR  N    EL+ +VI+G+  Y   + W  ++N P   +++GSP+   DLRA  +  C  C I++     ND     +DK AI+ +  I++M   + + +                 PI+++ R      +   I    NDS V              +  ++PFA G  F  S + S + T Y N +  + I++L+ G  + E+E +   G GL         R   +++  L +  +  + +IS +YDG L        Y  LF  AL    +LC+GLYR        +    RYV T+P     +  TDQV+  +  D
Sbjct:  768 DDQSKDFDFEKTEMKYDSTGMFHWSPAKSLEDCILDRNQAAMTVLNGHVVVCLFADPDSPLIGLRNLVMPLRASNFHYHELKHVVIVGSVDYIRRE-WKMLQNLPKISVLNGSPLSRADLRAVNVNLCDMCCILSAKVPSNDDPT-LADKEAILASLNIKAMTFDDTIGVLSQRGPEFDNLSATAGSPIVLQRRGSVYGANVPMITELVNDSNVQFLDQDDDDDPDTELYLTQPFACGTAFAVSVLDSLMSTTYFNQNALTLIRSLITGGATPELELILAEGAGL---------RGGYSTVESLSNRDRCRVGQIS-LYDGPLAQFGECGKYGDLFVAALKSYGMLCIGLYRFRDTSSSCDASSKRYVITNPPDDFSLLPTDQVFVLMQFD 1146

[Close]

BLAST of Calcium-activated potassium channel subunit alpha-1 vs. Ensembl Fly
Match: slo (gene:FBgn0003429 transcript:FBtr0100627)

HSP 1 Score: 241.121 bits (614), Expect = 2.935e-65
Identity = 160/556 (28.78%), Postives = 276/556 (49.64%), Query Frame = 2

Query:  326 MISKSTIVGRFLNFVKLISQLTSWGIFVVFTFNQVNANYLIGDCFDVEGANLQWIDFALNIFCLFHFTLRAFAANDILKFWIQPTTMIEITVIPNILLTSFLPVRRQGFSFLRIYYLRELCNTIAVSFGILKVNSKFEMTKVIFYIISLWLISAGLFHMFEGIGNFWEIPL-FN--QQLSFWRCCYFMLVTISTVGFGSVNPLTIFGRIVVLVYIIYGITMFVTVLPNVIRTIQNL-KYKNRYISKGNERHIIVCGKFESLTIIAFLKAFKRERFKGSVRNVKIVTMNKDLYDENLLMYMKRFSNPIKYLIGNLSNRKDLKRVNIQKAKLSVILSTPFTNKISEDDIDNIMTAMILKSQRKNMRTIVQLHLYSNKVLLKMSPMWNQNRSDIILCIDELKLGLMAYNCLTPGIATLVINLVTFT--KSKSVSELWRKDYENGLKVLLYNVQFSDCFHGMSCLEVALIVYKLWDVCLLA--IKCVNKSTDDYVLINPMIENIKIDTDSMIAIVMARDEASSNKLIFYCSKCSP--QNQSEICQCYLEATKNSPRGHYE 1963
            +IS  T  GR L  +  I  + S  I+ V   ++      +  C        Q ID A NIF + +F +R  AA+D L F ++  + ++   IP   ++ +L     G  FLR   L  + + +     +LK +S   + +++   IS+WL +AG+ H+ E  G+    PL FN   +LS+W C YF++VT+STVG+G V   T+ GR  ++ +++ G+ MF + +P +I  + +  KY      +  +RHI+VCG     ++  FLK F  E  +    +V++V +++   D  L    KR    +++  G + N  DL+RV + +A   ++L+  +      +D  NIM  + +K+   ++R I+QL  Y NK  L   P W+  + D ++C+ ELKLG +A +CL PG +T++ NL      K+   ++ W+ DY  G    +Y    S  F GM+  + + + +    + LLA  IK   +  D  + INP    I+ +T     I  + DE    +  FYC  C    ++++ I +C  +     PR  ++
Sbjct:  118 LISGQTTTGRILVVLVFILSIASLIIYFVDASSEE-----VERCQKWSNNITQQIDLAFNIFFMVYFFIRFIAASDKLWFMLEMYSFVDYFTIPPSFVSIYLDRTWIGLRFLRALRLMTVPDILQY-LNVLKTSSSIRLAQLVSIFISVWLTAAGIIHLLENSGD----PLDFNNAHRLSYWTCVYFLIVTMSTVGYGDVYCETVLGRTFLVFFLLVGLAMFASSIPEIIELVGSGNKYGGELKREHGKRHIVVCGHITYESVSHFLKDFLHEDREDV--DVEVVFLHRKPPDLELEGLFKRHFTTVEFFQGTIMNPIDLQRVKVHEADACLVLANKYCQDPDAEDAANIMRVISIKNYSDDIRVIIQLMQYHNKAYLLNIPSWDWKQGDDVICLAELKLGFIAQSCLAPGFSTMMANLFAMRSFKTSPDTQAWQNDYLQGTGCEMYTETLSPSFTGMTFPQASELCFSKLKLLLLAIEIKGAEEGADSKISINPRGAKIQANTQGFF-IAQSADEV--KRAWFYCKACHEDIKDETLIKKCKCKNLTVQPRSKFD 658

HSP 2 Score: 130.568 bits (327), Expect = 2.609e-30
Identity = 109/391 (27.88%), Postives = 174/391 (44.50%), Query Frame = 2

Query: 2033 DSKSEEIDIN-SYTGLDRTGSFYWAPEPNFEDVCLDIETAESRSLSDHILVCL-CGIGHGTIDLCNFMMPLRFQNLQNSELRTIVILGNKSYFEADKWTNIKNFPMFLIIDGSPIQSRDLRAAGLLKCHTCVIING----NDKTVGFSDKSAIICATLIRSMRKLNKLKI-----------------PIMIEIRKDEIAHHFSSIHSHNNDSKV-------------SVQHSEPFARGILFTNSTVYSCIYTVYKNPDTFSFIKTLLNGRYSDEIESMFGSGVGLLPQXXXXXXXXXXXXIIKLFSVIQPPLNEISRVYDGIL-------DYACLFEWALMEKRILCLGLYRL-------NFGRNRYVFTHPEKSTEIFSTDQVYCCVSSD 3055
            D +S++ D   +    D TG F+W+P  + ED  LD   A    L+ H++VCL        I L N +MPLR  N    EL+ +VI+G+  Y   + W  ++N P   +++GSP+   DLRA  +  C  C I++     ND     +DK AI+ +  I++M   + + +                 PI+++ R      +   I    NDS V              +  ++PFA G  F  S + S + T Y N +  + I++L+ G  + E+E +   G GL         R   +++  L +  +  + +IS +YDG L        Y  LF  AL    +LC+GLYR        +    RYV T+P     +  TDQV+  +  D
Sbjct:  760 DDQSKDFDFEKTEMKYDSTGMFHWSPAKSLEDCILDRNQAAMTVLNGHVVVCLFADPDSPLIGLRNLVMPLRASNFHYHELKHVVIVGSVDYIRRE-WKMLQNLPKISVLNGSPLSRADLRAVNVNLCDMCCILSAKVPSNDDPT-LADKEAILASLNIKAMTFDDTIGVLSQRGPEFDNLSATAGSPIVLQRRGSVYGANVPMITELVNDSNVQFLDQDDDDDPDTELYLTQPFACGTAFAVSVLDSLMSTTYFNQNALTLIRSLITGGATPELELILAEGAGL---------RGGYSTVESLSNRDRCRVGQIS-LYDGPLAQFGECGKYGDLFVAALKSYGMLCIGLYRFRDTSSSCDASSKRYVITNPPDDFSLLPTDQVFVLMQFD 1138

[Close]

BLAST of Calcium-activated potassium channel subunit alpha-1 vs. Ensembl Fly
Match: slo (gene:FBgn0003429 transcript:FBtr0330286)

HSP 1 Score: 241.121 bits (614), Expect = 3.251e-65
Identity = 159/544 (29.23%), Postives = 267/544 (49.08%), Query Frame = 2

Query:  326 MISKSTIVGRFLNFVKLISQLTSWGIFVVFTFNQVNANYLIGDCFDVEGANLQWIDFALNIFCLFHFTLRAFAANDILKFWIQPTTMIEITVIPNILLTSFLPVRRQGFSFLRIYYLRELCNTIAVSFGILKVNSKFEMTKVIFYIISLWLISAGLFHMFEGIGNFWEIPL-FN--QQLSFWRCCYFMLVTISTVGFGSVNPLTIFGRIVVLVYIIYGITMFVTVLPNVIR-TIQNLKYKNRYISKGNERHIIVCGKFESLTIIAFLKAFKRERFKGSVRNVKIVTMNKDLYDENLLMYMKRFSNPIKYLIGNLSNRKDLKRVNIQKAKLSVILSTPFTNKISEDDIDNIMTAMILKSQRKNMRTIVQLHLYSNKVLLKMSPMWNQNRSDIILCIDELKLGLMAYNCLTPGIATLVINLVTFT--KSKSVSELWRKDYENGLKVLLYNVQFSDCFHGMSCLEVALIVYKLWDVCLLA--IKCVNKSTDDYVLINPMIENIKIDTDSMIAIVMARDEASSNKLIFYCSKCSPQNQSEI----CQC 1921
            +IS  T  GR L  +  I  + S  I+ V   ++      +  C        Q ID A NIF + +F +R  AA+D L F ++  + ++   IP   ++ +L     G  FLR   L  + + +     +LK +S   + +++   IS+WL +AG+ H+ E  G+    PL FN   +LS+W C YF++VT+STVG+G V   T+ GR  ++ +++ G+ +F + +P +     Q  KY   Y     +RHI+VCG     ++  FLK F  E  +    +V++V +++   D  L   +KR    + +  G + N  DL+RV + +A   ++L+  +      +D  NIM  + +K+   ++R I+QL  Y NK  L   P W+  + D ++C+ ELKLG +A +CL PG +T++ NL      K+   ++ W+ DY  G    +Y    S  F GM+  + + + +    + LLA  IK   +  D  + INP    I+ +T     I  + DE    +  FYC  C    + E     C+C
Sbjct:  101 LISGQTTTGRILVVLVFILSIASLIIYFVDASSEE-----VERCQKWSNNITQQIDLAFNIFFMVYFFIRFIAASDKLWFMLEMYSFVDYFTIPPSFVSIYLDRTWIGLRFLRALRLMTVPDILQY-LNVLKTSSSIRLAQLVSIFISVWLTAAGIIHLLENSGD----PLDFNNAHRLSYWTCVYFLIVTMSTVGYGDVYCETVLGRTFLVFFLLVGLAVFASWIPEITELAAQRSKYGGTYSKDPRKRHIVVCGHITYESVSHFLKDFLHEDREDV--DVEVVFLHRKEPDLELEGLLKRHYTTVAFFQGTMMNAVDLERVKVHEADACLVLANKYCQDPDAEDAANIMRVISIKNYSDDIRVIIQLMQYHNKAYLLNIPSWDWKQGDDVICLAELKLGFIAQSCLAPGFSTMMANLFAMRSFKTSPDTQAWQNDYLQGTGCEMYTETLSPSFTGMTFPQASELCFSKLKLLLLAIEIKGAEEGADSKISINPRGAKIQANTQGFF-IAQSADEV--KRAWFYCKACHEDIKDETLIKKCKC 629

HSP 2 Score: 130.568 bits (327), Expect = 2.883e-30
Identity = 109/391 (27.88%), Postives = 174/391 (44.50%), Query Frame = 2

Query: 2033 DSKSEEIDIN-SYTGLDRTGSFYWAPEPNFEDVCLDIETAESRSLSDHILVCL-CGIGHGTIDLCNFMMPLRFQNLQNSELRTIVILGNKSYFEADKWTNIKNFPMFLIIDGSPIQSRDLRAAGLLKCHTCVIING----NDKTVGFSDKSAIICATLIRSMRKLNKLKI-----------------PIMIEIRKDEIAHHFSSIHSHNNDSKVS-------------VQHSEPFARGILFTNSTVYSCIYTVYKNPDTFSFIKTLLNGRYSDEIESMFGSGVGLLPQXXXXXXXXXXXXIIKLFSVIQPPLNEISRVYDGIL-------DYACLFEWALMEKRILCLGLYRL-------NFGRNRYVFTHPEKSTEIFSTDQVYCCVSSD 3055
            D +S++ D   +    D TG F+W+P  + ED  LD   A    L+ H++VCL        I L N +MPLR  N    EL+ +VI+G+  Y   + W  ++N P   +++GSP+   DLRA  +  C  C I++     ND     +DK AI+ +  I++M   + + +                 PI+++ R      +   I    NDS V              +  ++PFA G  F  S + S + T Y N +  + I++L+ G  + E+E +   G GL         R   +++  L +  +  + +IS +YDG L        Y  LF  AL    +LC+GLYR        +    RYV T+P     +  TDQV+  +  D
Sbjct:  802 DDQSKDFDFEKTEMKYDSTGMFHWSPAKSLEDCILDRNQAAMTVLNGHVVVCLFADPDSPLIGLRNLVMPLRASNFHYHELKHVVIVGSVDYIRRE-WKMLQNLPKISVLNGSPLSRADLRAVNVNLCDMCCILSAKVPSNDDPT-LADKEAILASLNIKAMTFDDTIGVLSQRGPEFDNLSATAGSPIVLQRRGSVYGANVPMITELVNDSNVQFLDQDDDDDPDTELYLTQPFACGTAFAVSVLDSLMSTTYFNQNALTLIRSLITGGATPELELILAEGAGL---------RGGYSTVESLSNRDRCRVGQIS-LYDGPLAQFGECGKYGDLFVAALKSYGMLCIGLYRFRDTSSSCDASSKRYVITNPPDDFSLLPTDQVFVLMQFD 1180

[Close]

BLAST of Calcium-activated potassium channel subunit alpha-1 vs. Ensembl Zebrafish
Match: kcnma1a (potassium large conductance calcium-activated channel, subfamily M, alpha member 1a [Source:ZFIN;Acc:ZDB-GENE-070202-9])

HSP 1 Score: 348.977 bits (894), Expect = 2.585e-102
Identity = 267/982 (27.19%), Postives = 448/982 (45.62%), Query Frame = 2

Query:  323 IMISKSTIVGRFLNFVKLISQLTSWGIFVVFTFNQVNANYLIGDCFDVEGANLQWIDFALNIFCLFHFTLRAFAANDILKFWIQPTTMIEITVIPNILLTSFLPVRRQGFSFLRIYYLRELCNTIAVSFGILKVNSKFEMTKVIFYIISLWLISAGLFHMFEGIGNFWEIPLFNQQLSFWRCCYFMLVTISTVGFGSVNPLTIFGRIVVLVYIIYGITMFVTVLPNVIRTIQNL-KYKNRYISKGNERHIIVCGKFESLTIIAFLKAF-KRERFKGSVRNVKIVTMNKDLYDENLLMYMKRFSNPIKYLIGNLSNRKDLKRVNIQKAKLSVILSTPFTNKISEDDIDNIMTAMILKSQRKNMRTIVQLHLYSNKVLLKMSPMWNQNRSDIILCIDELKLGLMAYNCLTPGIATLVINLVTFTKSKSVSE-LWRKDYENGLKVLLYNVQFSDCFHGMSCLEVALIVYKLWDVCLLAIKCVNKSTDDYVLINPMIENIKIDTDSMIAIVMARDEASSNKLIFYCSKCSPQ--NQSEICQCYLEATKNSPRGHYESNLQFENQRINESFRSA--------YEFPTIDSKSEEID-----INSYTGLDRTGSFYWAPEPNFEDVCLDIETAESRSLSDHILVCLCG-IGHGTIDLCNFMMPLRFQNLQNSELRTIVILGNKSYFEADKWTNIKNFPMFLIIDGSPIQSRDLRAAGLLKCHTCVIINGNDKTV---GFSDKSAIICATLIRSMRKLNKLKI---------------------PIMIEIRKDEI--AHHFSSIHSHNNDSKV-------------SVQHSEPFARGILFTNSTVYSCIYTVYKNPDTFSFIKTLLNGRYSDEIESMFGSGVGL-----LPQXXXXXXXXXXXXIIKLFSVIQPPLNEISRVYDGILDYACLFEWALMEKRILCLGLYRLNFGR--------NRYVFTHPEKSTEIFSTDQVYCCVSSD 3055
            +MIS  T+ GR L  +     + + GI+ + + + + +       F ++      ID A N+F L +F LR  AAND L FW++  ++++   +P + ++ +L     G  FLR   L +    +     ILK ++  ++  +    IS WL +AG  H+ E  G+ WE    +Q LS+W C Y ++VT+STVG+G V   T  GR+ ++ +I+ G+ MF + +P +I  I N  KY   Y +    +HI+VCG     ++  FLK F  ++R      NV+IV ++    +  L    KR    +++  G++ N  DL RV I+ A   +IL+  +      +D  NIM  + +K+    +R I Q+  Y NK  L   P WN    D  +C+ ELK G +A +CL  G++T++ NL +      + E  W+K Y  G+   +Y    S  F G+S   V  + Y    + L+AI+  ++  +  +LINP   ++K+  +  +   +A D     +  FYC  C     +   I +C  +  ++     + S L  + ++ N   R++           P +   +E+I+     +  Y   D TG F+W P    E V L    A    LS H++VC+ G +    + L N +MPLR  N    EL+ IV +G+  Y   + W  + NFP   I+ G+P+   DLRA  +  C  CVI++ N   +      DK  I+ +  I+SM+  + + +                     P+   +R+  +    +   I    NDS V              +  ++PFA G  F  S + S +   Y N +  + I+TL+ G  + E+E++      L      PQ  ++ +R      +   ++   P  ++    DG   Y  LF  AL    +LC G+YRL             RYV T+P    E+  TD ++C +  D
Sbjct:  122 VMISAQTLTGRVLVVLVFALSIGALGIYFIDSSDPIESCQNFYKDFTLQ------IDMAFNVFFLLYFGLRFIAANDKLWFWLEVNSVVDFFTVPPVFVSVYLNRSWLGLRFLRALRLIQFSEILQF-LNILKTSNSIKLVNLCSIFISTWLTAAGFIHLVENSGDPWENFQNSQPLSYWECVYLLMVTMSTVGYGDVYARTTLGRLFMVFFILGGLAMFASYVPEIIELIGNRKKYGGSYSAVNGRKHIVVCGHITLESVSNFLKDFLHKDR---DDVNVEIVFLHNISPNLELEALFKRHFTQVEFYQGSVLNPHDLARVKIESADACLILANKYCADPDAEDASNIMRVISIKNYHPKIRIITQMLQYHNKAHLLNIPSWNWKEGDDAICLAELKAGFIAQSCLAQGLSTMLANLFSMRSYIKIEEDTWQKYYLEGVANEMYTEYLSSAFVGLSFPTVCELCYVKLKLLLIAIEYKSEQRESSILINPG-NHVKMQ-EGTLGFFIASDAKEVKRAFFYCKACHDDITDPKRIKKCGCKRIED----EHPSTLSPKKKQRNGGMRNSPNCSPKMMRHDPLLIPGNEQIESMDANVKRY---DSTGMFHWCPSKEIEKVILTRSEASMTVLSGHVVVCIFGDVTSALVGLRNLVMPLRASNFHYHELKPIVFVGSLDYLRRE-WETLHNFPKVFILPGTPLSRADLRAVNINLCDMCVILSANQNNIDDASLQDKECILASLNIKSMQFDDSIGVLQANSQGFTPPGMDRSSPDNSPVHGLVRQASVTTGSNIPIITELVNDSNVQFLDQDDDDDPDTELYLTQPFACGTAFAVSVLDSLMSATYFNDNILTLIRTLVTGGATPELEALLAEENALRGGYSTPQTLANRDRCR----VAQLALYDGPFADLG---DGGC-YGDLFCKALKTYNMLCFGIYRLRDAHLGAPSQCTKRYVITNPPYEFEMVPTDLIFCLMQFD 1075

[Close]

BLAST of Calcium-activated potassium channel subunit alpha-1 vs. Ensembl Zebrafish
Match: kcnma1a (potassium large conductance calcium-activated channel, subfamily M, alpha member 1a [Source:ZFIN;Acc:ZDB-GENE-070202-9])

HSP 1 Score: 343.199 bits (879), Expect = 3.720e-100
Identity = 267/985 (27.11%), Postives = 448/985 (45.48%), Query Frame = 2

Query:  323 IMISKSTIVGRFLNFVKLISQLTSWGIFVVFTFNQVNANYLIGDCFDVEGANLQWIDFALNIFCLFHFTLRAFAANDILKFWIQPTTMIEITVIPNILLTSFLPVRRQGFSFLRIYYLRELCNTIAVSFGILKVNSKFEMTKVIFYIISLWLISAGLFHMFEGIGNFWEIPLFNQQLSFWRCCYFMLVTISTVGFGSVNPLTIFGRIVVLVYIIYGITMFVTVLPNVIRTIQNL-KYKNRYISKGNERHIIVCGKFESLTIIAFLKAFKRERFKGSVRNVKIVTMNKDLYDENLLMYMKRFSNPIKYLIGNLSNRKDLKRVNIQKAKLSVILSTPFTNKISEDDIDNIMTAMILKSQRKNMRTIVQLHLYSNKVLLKMSPMWNQNRSDIILCIDELKLGLMAYNCLTPGIATLVINLVTFTKSKSVSE-LWRKDYENGLKVLLYNVQFSDCFHGMSCLEVALIVYKLWDVCLLAIKCVNKSTDD----YVLINPMIENIKIDTDSMIAIVMARDEASSNKLIFYCSKCSPQ--NQSEICQCYLEATKNSPRGHYESNLQFENQRINESFRSA--------YEFPTIDSKSEEID-----INSYTGLDRTGSFYWAPEPNFEDVCLDIETAESRSLSDHILVCLCG-IGHGTIDLCNFMMPLRFQNLQNSELRTIVILGNKSYFEADKWTNIKNFPMFLIIDGSPIQSRDLRAAGLLKCHTCVIINGNDKTV---GFSDKSAIICATLIRSMRKLNKLKI---------------------PIMIEIRKDEI--AHHFSSIHSHNNDSKV-------------SVQHSEPFARGILFTNSTVYSCIYTVYKNPDTFSFIKTLLNGRYSDEIESMFGSGVGL-----LPQXXXXXXXXXXXXIIKLFSVIQPPLNEISRVYDGILDYACLFEWALMEKRILCLGLYRLNFGR--------NRYVFTHPEKSTEIFSTDQVYCCVSSD 3055
            +MIS  T+ GR L  +     + + GI+ + + + + +       F ++      ID A N+F L +F LR  AAND L FW++  ++++   +P + ++ +L     G  FLR   L +    +     ILK ++  ++  +    IS WL +AG  H+ E  G+ WE    +Q LS+W C Y ++VT+STVG+G V   T  GR+ ++ +I+ G+ MF + +P +I  I N  KY   Y +    +HI+VCG     ++  FLK F   + +  V NV+IV ++    +  L    KR    +++  G++ N  DL RV I+ A   +IL+  +      +D  NIM  + +K+    +R I Q+  Y NK  L   P WN    D  +C+ ELK G +A +CL  G++T++ NL +      + E  W+K Y  G+   +Y    S  F G+S   V  + Y    + L+AI+  ++  +      +LINP   ++K+  +  +   +A D     +  FYC  C     +   I +C  +  ++     + S L  + ++ N   R++           P +   +E+I+     +  Y   D TG F+W P    E V L    A    LS H++VC+ G +    + L N +MPLR  N    EL+ IV +G+  Y   + W  + NFP   I+ G+P+   DLRA  +  C  CVI++ N   +      DK  I+ +  I+SM+  + + +                     P+   +R+  +    +   I    NDS V              +  ++PFA G  F  S + S +   Y N +  + I+TL+ G  + E+E++      L      PQ  ++ +R      +   ++   P  ++    DG   Y  LF  AL    +LC G+YRL             RYV T+P    E+  TD ++C +  D
Sbjct:  139 VMISAQTLTGRVLVVLVFALSIGALGIYFIDSSDPIESCQNFYKDFTLQ------IDMAFNVFFLLYFGLRFIAANDKLWFWLEVNSVVDFFTVPPVFVSVYLNRSWLGLRFLRALRLIQFSEILQF-LNILKTSNSIKLVNLCSIFISTWLTAAGFIHLVENSGDPWENFQNSQPLSYWECVYLLMVTMSTVGYGDVYARTTLGRLFMVFFILGGLAMFASYVPEIIELIGNRKKYGGSYSAVNGRKHIVVCGHITLESVSNFLKDF-LHKDRDDV-NVEIVFLHNISPNLELEALFKRHFTQVEFYQGSVLNPHDLARVKIESADACLILANKYCADPDAEDASNIMRVISIKNYHPKIRIITQMLQYHNKAHLLNIPSWNWKEGDDAICLAELKAGFIAQSCLAQGLSTMLANLFSMRSYIKIEEDTWQKYYLEGVANEMYTEYLSSAFVGLSFPTVCELCYVKLKLLLIAIEYKSEQRESRSRKRILINPG-NHVKMQ-EGTLGFFIASDAKEVKRAFFYCKACHDDITDPKRIKKCGCKRIED----EHPSTLSPKKKQRNGGMRNSPNCSPKMMRHDPLLIPGNEQIESMDANVKRY---DSTGMFHWCPSKEIEKVILTRSEASMTVLSGHVVVCIFGDVTSALVGLRNLVMPLRASNFHYHELKPIVFVGSLDYLRRE-WETLHNFPKVFILPGTPLSRADLRAVNINLCDMCVILSANQNNIDDASLQDKECILASLNIKSMQFDDSIGVLQANSQGFTPPGMDRSSPDNSPVHGLVRQASVTTGSNIPIITELVNDSNVQFLDQDDDDDPDTELYLTQPFACGTAFAVSVLDSLMSATYFNDNILTLIRTLVTGGATPELEALLAEENALRGGYSTPQTLANRDRCR----VAQLALYDGPFADLG---DGGC-YGDLFCKALKTYNMLCFGIYRLRDAHLGAPSQCTKRYVITNPPYEFEMVPTDLIFCLMQFD 1096

[Close]

BLAST of Calcium-activated potassium channel subunit alpha-1 vs. Ensembl Zebrafish
Match: kcnma1a (potassium large conductance calcium-activated channel, subfamily M, alpha member 1a [Source:ZFIN;Acc:ZDB-GENE-070202-9])

HSP 1 Score: 322.783 bits (826), Expect = 1.103e-92
Identity = 217/748 (29.01%), Postives = 362/748 (48.40%), Query Frame = 2

Query:  323 IMISKSTIVGRFLNFVKLISQLTSWGIFVVFTFNQVNANYLIGDCFDVEGANLQWIDFALNIFCLFHFTLRAFAANDILKFWIQPTTMIEITVIPNILLTSFLPVRRQGFSFLRIYYLRELCNTIAVSFGILKVNSKFEMTKVIFYIISLWLISAGLFHMFEGIGNFWEIPLFNQQLSFWRCCYFMLVTISTVGFGSVNPLTIFGRIVVLVYIIYGITMFVTVLPNVIRTIQNL-KYKNRYISKGNERHIIVCGKFESLTIIAFLKAFKRERFKGSVRNVKIVTMNKDLYDENLLMYMKRFSNPIKYLIGNLSNRKDLKRVNIQKAKLSVILSTPFTNKISEDDIDNIMTAMILKSQRKNMRTIVQLHLYSNKVLLKMSPMWNQNRSDIILCIDELKLGLMAYNCLTPGIATLVINLVTFTKSKSVSE-LWRKDYENGLKVLLYNVQFSDCFHGMSCLEVALIVYKLWDVCLLAIKCVNKSTDDYVLINPMIENIKIDTDSMIAIVMARDEASSNKLIFYCSKCSPQ--NQSEICQCYLEATKNSPRGHYESNLQFENQRINESFRSA--------YEFPTIDSKSEEID-----INSYTGLDRTGSFYWAPEPNFEDVCLDIETAESRSLSDHILVCLCG-IGHGTIDLCNFMMPLRFQNLQNSELRTIVILGNKSYFEADKWTNIKNFPMFLIIDGSPIQSRDLRAAGLLKCHTCVIINGNDKTV---GFSDKSAIICATLIRSMR 2503
            +MIS  T+ GR L  +     + + GI+ + + + + +       F ++      ID A N+F L +F LR  AAND L FW++  ++++   +P + ++ +L     G  FLR   L +    +     ILK ++  ++  +    IS WL +AG  H+ E  G+ WE    +Q LS+W C Y ++VT+STVG+G V   T  GR+ ++ +I+ G+ MF + +P +I  I N  KY   Y +    +HI+VCG     ++  FLK F   + +  V NV+IV ++    +  L    KR    +++  G++ N  DL RV I+ A   +IL+  +      +D  NIM  + +K+    +R I Q+  Y NK  L   P WN    D  +C+ ELK G +A +CL  G++T++ NL +      + E  W+K Y  G+   +Y    S  F G+S   V  + Y    + L+AI+  ++  +  +LINP   ++K+  +  +   +A D     +  FYC  C     +   I +C  +  ++     + S L  + ++ N   R++           P +   +E+I+     +  Y   D TG F+W P    E V L    A    LS H++VC+ G +    + L N +MPLR  N    EL+ IV +G+  Y   + W  + NFP   I+ G+P+   DLRA  +  C  CVI++ N   +      DK  I+ +  I+SM+
Sbjct:  139 VMISAQTLTGRVLVVLVFALSIGALGIYFIDSSDPIESCQNFYKDFTLQ------IDMAFNVFFLLYFGLRFIAANDKLWFWLEVNSVVDFFTVPPVFVSVYLNRSWLGLRFLRALRLIQFSEILQF-LNILKTSNSIKLVNLCSIFISTWLTAAGFIHLVENSGDPWENFQNSQPLSYWECVYLLMVTMSTVGYGDVYARTTLGRLFMVFFILGGLAMFASYVPEIIELIGNRKKYGGSYSAVNGRKHIVVCGHITLESVSNFLKDF-LHKDRDDV-NVEIVFLHNISPNLELEALFKRHFTQVEFYQGSVLNPHDLARVKIESADACLILANKYCADPDAEDASNIMRVISIKNYHPKIRIITQMLQYHNKAHLLNIPSWNWKEGDDAICLAELKAGFIAQSCLAQGLSTMLANLFSMRSYIKIEEDTWQKYYLEGVANEMYTEYLSSAFVGLSFPTVCELCYVKLKLLLIAIEYKSEQRESSILINPG-NHVKMQ-EGTLGFFIASDAKEVKRAFFYCKACHDDITDPKRIKKCGCKRIED----EHPSTLSPKKKQRNGGMRNSPNCSPKMMRHDPLLIPGNEQIESMDANVKRY---DSTGMFHWCPSKEIEKVILTRSEASMTVLSGHVVVCIFGDVTSALVGLRNLVMPLRASNFHYHELKPIVFVGSLDYLRRE-WETLHNFPKVFILPGTPLSRADLRAVNINLCDMCVILSANQNNIDDASLQDKECILASLNIKSMQ 867

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BLAST of Calcium-activated potassium channel subunit alpha-1 vs. Ensembl Zebrafish
Match: CABZ01092907.1 (potassium large conductance calcium-activated channel, subfamily M, alpha member 1b [Source:NCBI gene;Acc:798583])

HSP 1 Score: 226.868 bits (577), Expect = 1.538e-64
Identity = 144/456 (31.58%), Postives = 233/456 (51.10%), Query Frame = 2

Query:  323 IMISKSTIVGRFLNFVKLISQLTSWGIFVVFTFNQVNANYLIGDCFDVEGANLQWIDFALNIFCLFHFTLRAFAANDILKFWIQPTTMIEITVIPNILLTSFLPVRRQGFSFLRIYYLRELCNTIAVSFGILKVNSKFEMTKVIFYIISLWLISAGLFHMFEGIGNFWEIPLFNQQLSFWRCCYFMLVTISTVGFGSVNPLTIFGRIVVLVYIIYGITMFVTVLPNVIRTIQNL-KYKNRYISKGNERHIIVCGKFESLTIIAFLKAFKRERFKGSVRNVKIVTMNKDLYDENLLMYMKRFSNPIKYLIGNLSNRKDLKRVNIQKAKLSVILSTPFTNKISEDDIDNIMTAMILKSQRKNMRTIVQLHLYSNKVLLKMSPMWNQNRSDIILCIDELKLGLMAYNCLTPGIATLVINLVTFTKSKSVSE-LWRKDYENGLKVLLYNVQFSDCFHGMS 1684
            +MIS  T+ GR L  V L+  L+   + + F    ++++  I  C   +      ID A N+F L +F LR  AAND L FW++  ++++   +P + ++ +L     G  FLR   L +    +     ILK ++  ++  +    IS WL +AG  H+ E  G+ WE    +Q LS+W C Y ++VT+STVG+G V   T  GR+ ++ +I+ G+ MF + +P +I  I N  KY   Y +    +HI+VCG     ++  FLK F  +  +  V NV+IV ++    +  L    KR    +++  G++ N  DL RV I+ A   +IL+  +      +D  NIM  + +K+    +R I Q+  Y NK  L   P WN    D  +C+ ELKLG +A +CL  G++T++ NL +      + E  W+K Y  G+   +Y    S  F G+S
Sbjct:   10 VMISAQTLTGRVL--VVLVFALSIGALVIYF----IDSSDPIESCEHFDKNFTLQIDMAFNVFFLLYFGLRFIAANDKLWFWLEVNSVVDFFTVPPVFVSVYLNRSWLGLRFLRALRLIQFSEILQF-LNILKTSNSIKLVNLCSIFISTWLTAAGFIHLVENSGDPWENFQNSQPLSYWECVYLLMVTMSTVGYGDVCAKTTLGRLFMVFFILGGLAMFASYVPEIIELIGNRKKYGGSYSAVNGRKHIVVCGHITLESVSNFLKDFLHKD-RDDV-NVEIVFLHNISPNLELEALFKRHFTQVEFYQGSVLNPHDLARVKIESADACLILANKYCADPDAEDASNIMRVISIKNYHPKIRIITQMLQYHNKAHLLNIPSWNWKEGDDAICLAELKLGFIAQSCLAQGLSTMLANLFSMRSYIKIEEDTWQKYYLEGVANEMYTEYLSSAFVGLS 456

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BLAST of Calcium-activated potassium channel subunit alpha-1 vs. Ensembl Zebrafish
Match: kcnt1 (potassium channel, subfamily T, member 1 [Source:ZFIN;Acc:ZDB-GENE-091231-1])

HSP 1 Score: 90.1225 bits (222), Expect = 1.023e-17
Identity = 88/355 (24.79%), Postives = 154/355 (43.38%), Query Frame = 2

Query:  845 QQLSFWRCCYFMLVTISTVGFGSVNPLTIFGRIVVLVYIIYGITMFVTVLPNVIRTIQNLKYKNRYISKGN--------ERHIIVC-GKFESLTIIAFLKAFKRERFKGSVRNVKIVTMNKDLYDENLLMYMKRFSNPIKYLIGNLSNRKDLKRVNIQKAKLSVILSTPFTNKISEDDIDNIMTAMILKSQRKNMRTIVQLHLYSNKVLLKMSPMWNQNRSDIILCIDELKLGLMAYNCLTPGIATLVINLVTFTKSKS---VSELWRKDYENGLKVLLYNVQFSDC-----FHGMSCLEVALIVYKLWDVCLLAIKCVNKSTDDYVLINPMIENIKIDTDSMIAIVMARDEASS 1858
            + LS +   YF +VT STVGFG V P     +++V+V I   +     VLP     +  L +  R  S GN        ERH+++C    +   ++ FL  F           V +     D+    +L  +  +S  + YL G+    +DL R  +  A+   ILS+         D   I+ A  +K    N    VQ+    NK  +K         +D ++C +E K  ++A NCL P  +TL+  LV  ++ +      E W++ Y       +Y+++  D      ++  S    A   +K + VC++ +K   +  +  +L+NP   +I   +D+   I + ++E S+
Sbjct:  209 KSLSLFNALYFCIVTFSTVGFGDVTPQIWPSQLLVVVMICVAL----VVLPLQFEELIYL-WMERQKSGGNYSRHRAQTERHVVLCVSTLKIDLLMDFLNEFYAHPHTQDYYVVILCPCEVDVQVRRILQ-IPLWSQRVIYLQGSALKNQDLLRAKMDDAEACFILSSRNEADRMAADHQTILRAWAVKDFAPNCPLYVQILKPENKFHVKF--------ADHVVCEEEFKYAMLALNCLCPATSTLITLLVHTSRGQEGQQSPEQWQRMYGRCSGNEVYHIRLGDSMFFREYNSKSFTYAAFHAHKKYGVCMIGVK---REDNKSILLNPGPRHIMSASDTCYYINITKEENSA 546

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BLAST of Calcium-activated potassium channel subunit alpha-1 vs. Ensembl Xenopus
Match: KCNMA1 (potassium calcium-activated channel subfamily M alpha 1 [Source:NCBI gene;Acc:100491898])

HSP 1 Score: 343.969 bits (881), Expect = 2.078e-100
Identity = 268/976 (27.46%), Postives = 446/976 (45.70%), Query Frame = 2

Query:  323 IMISKSTIVGRFLNFVKLISQLTSWGIFVVFTFNQVNANYLIGDCFDVEGANLQWIDFALNIFCLFHFTLRAFAANDILKFWIQPTTMIEITVIPNILLTSFLPVRRQGFSFLRIYYLRELCNTIAVSFGILKVNSKFEMTKVIFYIISLWLISAGLFHMFEGIGNFWEIPLFNQQLSFWRCCYFMLVTISTVGFGSVNPLTIFGRIVVLVYIIYGITMFVTVLPNVIRTIQNL-KYKNRYISKGNERHIIVCGKFESLTIIAFLKAF-KRERFKGSVRNVKIVTMNKDLYDENLLMYMKRFSNPIKYLIGNLSNRKDLKRVNIQKAKLSVILSTPFTNKISEDDIDNIMTAMILKSQRKNMRTIVQLHLYSNKVLLKMSPMWNQNRSDIILCIDELKLGLMAYNCLTPGIATLVINLVTFTKSKSVSE-LWRKDYENGLKVLLYNVQFSDCFHGMSCLEVALIVYKLWDVCLLAIKCVNKSTDDYVLINPMIENIKIDTDSMIAIVMARDEASSNKLIFYCSKCSPQ--NQSEICQCYLEATKNSPRGHYESNLQFENQRINESFRSAYEF----PTIDSKSEEI---DINSYTGLDRTGSFYWAPEPNFEDVCLDIETAESRSLSDHILVCLCG-IGHGTIDLCNFMMPLRFQNLQNSELRTIVILGNKSYFEADKWTNIKNFPMFLIIDGSPIQSRDLRAAGLLKCHTCVIINGNDKTV---GFSDKSAIICATLIRSMRKLNKLKI----------PIMIEIRKDE-----IAHHFSSIHSHN--------NDSKV-------------SVQHSEPFARGILFTNSTVYSCIYTVYKNPDTFSFIKTLLNGRYSDEIESMFGSGVGL-----LPQXXXXXXXXXXXXIIKLFSVIQPPLNEISRVYDGILDYACLFEWALMEKRILCLGLYRLNFGR--------NRYVFTHPEKSTEIFSTDQVYCCVSSD 3055
            +MIS  T+ GR L  V  +  L+   + + F    ++++  I  C +        ID A NIF L +F LR  AAND L FW++  ++++   +P + ++ +L     G  FLR   L +    +     ILK ++  ++  +    IS WL +AG  H+ E  G+ W     +Q LS+W C Y ++VT+STVG+G V   T  GR+ ++ +I+ G+ MF + +P +I  I N  KY   Y +    +HI+VCG     ++  FLK F  ++R      NV+IV ++    +  L    KR    +++  G++ N  DL RV I+ A   +IL+  +      +D  NIM  + +K+    +R I Q+  Y NK  L   P WN    D  +C+ ELKLG +A +CL  G++T++ NL +      + E  W+K Y  G+   +Y    S  F G+S   V  + +    + ++AI+  ++  +  ++INP   ++KI  +  +   +A D     +  FYC  C     +   I +C  +  ++          +  N  + +S  S+       P + + +++I   D +S    D TG F+W P    + V L    A    LS H++VC+ G +    I + N +MPLR  N    EL+ IV +G+  Y + + W  + NFP   I+ G+P+   DLRA  +  C  CVI++ N   +      DK  I+ +  I+SM+  + + +          P M     D      +A   S     N        NDS V              +  ++PFA G  F  S + S +   Y N +  + I+TL+ G  + E+E++      L      PQ  ++ +R      +   ++   P  ++    DG   Y  L+  AL    +LC G+YRL             RYV T+P    E+  TD ++C +  D
Sbjct:  119 VMISAQTLTGRVL--VVTVFALSIGALMIYF----IDSSNPIETCQNFYKDFTLQIDMAFNIFFLLYFGLRFIAANDKLWFWLEVNSVVDFFTVPPVFVSVYLNRSWLGLRFLRALRLIQFSEILQF-LNILKTSNSIKLVNLCSIFISTWLTAAGFIHLVENSGDPWRNFENSQDLSYWECVYLLMVTMSTVGYGDVYAKTTLGRLFMVFFILGGLAMFASYVPEIIELIGNRKKYGGSYSAVSGRKHIVVCGHITLESVSNFLKDFLHKDR---DDVNVEIVFLHNISPNLELEALFKRHFTQVEFYQGSVLNPHDLARVKIESADACLILANKYCADPDAEDASNIMRVISIKNYHPKIRIITQMLQYHNKAHLLNIPSWNWKEGDDAICLAELKLGFIAQSCLAQGLSTMLANLFSMRSFIKIEEDTWQKYYLEGVSNEMYTEYLSSAFVGLSFPAVCELCFVKLKLLMIAIEFKSEKGESRIIINPG-NHVKI-KEGTLGFFIASDAKEVKRAFFYCKACHDDITDPKRIKKCACKRLEDEQPSALSPKKKQRNGGMRQSPNSSPNMMRHDPLLMTGNDQIDNMDSSSVKRYDSTGMFHWCPAKELDKVLLTRSEAAMTVLSGHVVVCIFGDMTSALIGVRNLVMPLRASNFHYHELKHIVFVGSLDYLKRE-WETLHNFPKVSILPGTPLSRADLRAVNINLCDMCVILSANQNNIDDTSLQDKECILASLNIKSMQFDDSIGLLQANSQGFTPPGMERSSPDNSPVHGVARQASITTGANIPIITELVNDSNVQFLDQDDDDDPDTELYLTQPFACGTAFAVSVLDSLMSATYFNDNILTLIRTLVTGGATPELEALIAEENALRGGYSTPQTLANRDRCR----VAQLALYDGPFADLG---DGGC-YGDLYCKALKTYNMLCFGIYRLRDAHLSTPSQCTKRYVITNPPYEFELVPTDLIFCLMQFD 1073

[Close]

BLAST of Calcium-activated potassium channel subunit alpha-1 vs. Ensembl Xenopus
Match: KCNMA1 (potassium calcium-activated channel subfamily M alpha 1 [Source:NCBI gene;Acc:100491898])

HSP 1 Score: 341.658 bits (875), Expect = 2.373e-99
Identity = 274/994 (27.57%), Postives = 451/994 (45.37%), Query Frame = 2

Query:  323 IMISKSTIVGRFLNFVKLISQLTSWGIFVVFTFNQVNANYLIGDCFDVEGANLQWIDFALNIFCLFHFTLRAFAANDILKFWIQPTTMIEITVIPNILLTSFLPVRRQGFSFLRIYYLRELCNTIAVSFGILKVNSKFEMTKVIFYIISLWLISAGLFHMFEGIGNFWEIPLFNQQLSFWRCCYFMLVTISTVGFGSVNPLTIFGRIVVLVYIIYGITMFVTVLPNVIRTIQNL-KYKNRYISKGNERHIIVCGKFESLTIIAFLKAF-KRERFKGSVRNVKIVTMNKDLYDENLLMYMKRFSNPIKYLIGNLSNRKDLKRVNIQKAKLSVILSTPFTNKISEDDIDNIMTAMILKSQRKNMRTIVQLHLYSNKVLLKMSPMWNQNRSDIILCIDELKLGLMAYNCLTPGIATLVINLVTFTKSKSVSE-LWRKDYENGLKVLLYNVQFSDCFHGMSCLEVALIVYKLWDVCLLAIKCVNKSTDDYVLINPMIENIKIDTDSMIAIVMARDEASSNKLIFYC-------------SKCSPQNQSEICQCYLEATK--NSP-RGHYESNLQFENQRINESFR-SAYEFP----------TIDSKSEEIDINSYTGLDRTGSFYWAPEPNFEDVCLDIETAESRSLSDHILVCLCG-IGHGTIDLCNFMMPLRFQNLQNSELRTIVILGNKSYFEADKWTNIKNFPMFLIIDGSPIQSRDLRAAGLLKCHTCVIINGNDKTV---GFSDKSAIICATLIRSMRKLNKLKI----------PIMIEIRKDE-----IAHHFSSIHSHN--------NDSKVS-------------VQHSEPFARGILFTNSTVYSCIYTVYKNPDTFSFIKTLLNGRYSDEIESMFGSGVGL-----LPQXXXXXXXXXXXXIIKLFSVIQPPLNEISRVYDGILDYACLFEWALMEKRILCLGLYRLNFGR--------NRYVFTHPEKSTEIFSTDQVYCCVSSD 3055
            +MIS  T+ GR L  V  +  L+   + + F    ++++  I  C +        ID A NIF L +F LR  AAND L FW++  ++++   +P + ++ +L     G  FLR   L +    +     ILK ++  ++  +    IS WL +AG  H+ E  G+ W     +Q LS+W C Y ++VT+STVG+G V   T  GR+ ++ +I+ G+ MF + +P +I  I N  KY   Y +    +HI+VCG     ++  FLK F  ++R      NV+IV ++    +  L    KR    +++  G++ N  DL RV I+ A   +IL+  +      +D  NIM  + +K+    +R I Q+  Y NK  L   P WN    D  +C+ ELKLG +A +CL  G++T++ NL +      + E  W+K Y  G+   +Y    S  F G+S   V  + +    + ++AI+  ++  +  ++INP   ++KI  +  +   +A D     +  FYC              KC+ + +S+  +  L+  K  N P      S L  + ++ N   R S    P          T + + + +D +S    D TG F+W P    + V L    A    LS H++VC+ G +    I + N +MPLR  N    EL+ IV +G+  Y + + W  + NFP   I+ G+P+   DLRA  +  C  CVI++ N   +      DK  I+ +  I+SM+  + + +          P M     D      +A   S     N        NDS V              +  ++PFA G  F  S + S +   Y N +  + I+TL+ G  + E+E++      L      PQ  ++ +R      +   ++   P  ++    DG   Y  L+  AL    +LC G+YRL             RYV T+P    E+  TD ++C +  D
Sbjct:  165 VMISAQTLTGRVL--VVTVFALSIGALMIYF----IDSSNPIETCQNFYKDFTLQIDMAFNIFFLLYFGLRFIAANDKLWFWLEVNSVVDFFTVPPVFVSVYLNRSWLGLRFLRALRLIQFSEILQF-LNILKTSNSIKLVNLCSIFISTWLTAAGFIHLVENSGDPWRNFENSQDLSYWECVYLLMVTMSTVGYGDVYAKTTLGRLFMVFFILGGLAMFASYVPEIIELIGNRKKYGGSYSAVSGRKHIVVCGHITLESVSNFLKDFLHKDR---DDVNVEIVFLHNISPNLELEALFKRHFTQVEFYQGSVLNPHDLARVKIESADACLILANKYCADPDAEDASNIMRVISIKNYHPKIRIITQMLQYHNKAHLLNIPSWNWKEGDDAICLAELKLGFIAQSCLAQGLSTMLANLFSMRSFIKIEEDTWQKYYLEGVSNEMYTEYLSSAFVGLSFPAVCELCFVKLKLLMIAIEFKSEKGESRIIINPG-NHVKI-KEGTLGFFIASDAKEVKRAFFYCKACHDDITDPKRIKKCACKRRSQFHKSPLQNKKKGNGPFEDEQPSALSPKKKQRNGGMRQSPNSSPNMMRHDPLLMTGNDQIDNMDSSSVKRYDSTGMFHWCPAKELDKVLLTRSEAAMTVLSGHVVVCIFGDMTSALIGVRNLVMPLRASNFHYHELKHIVFVGSLDYLKRE-WETLHNFPKVSILPGTPLSRADLRAVNINLCDMCVILSANQNNIDDTSLQDKECILASLNIKSMQFDDSIGLLQANSQGFTPPGMERSSPDNSPVHGVARQASITTGANIPIITELVNDSNVQFLDQDDDDDPDTELYLTQPFACGTAFAVSVLDSLMSATYFNDNILTLIRTLVTGGATPELEALIAEENALRGGYSTPQTLANRDRCR----VAQLALYDGPFADLG---DGGC-YGDLYCKALKTYNMLCFGIYRLRDAHLSTPSQCTKRYVITNPPYEFELVPTDLIFCLMQFD 1137

[Close]

BLAST of Calcium-activated potassium channel subunit alpha-1 vs. Ensembl Xenopus
Match: KCNMA1 (potassium calcium-activated channel subfamily M alpha 1 [Source:NCBI gene;Acc:100491898])

HSP 1 Score: 337.806 bits (865), Expect = 5.653e-98
Identity = 266/975 (27.28%), Postives = 444/975 (45.54%), Query Frame = 2

Query:  323 IMISKSTIVGRFLNFVKLISQLTSWGIFVVFTFNQVNANYLIGDCFDVEGANLQWIDFALNIFCLFHFTLRAFAANDILKFWIQPTTMIEITVIPNILLTSFLPVRRQGFSFLRIYYLRELCNTIAVSFGILKVNSKFEMTKVIFYIISLWLISAGLFHMFEGIGNFWEIPLFNQQLSFWRCCYFMLVTISTVGFGSVNPLTIFGRIVVLVYIIYGITMFVTVLPNVIRTIQNLK-YKNRYISKGNERHIIVCGKFESLTIIAFLKAFKRERFKGSVRNVKIVTMNKDLYDENLLMYMKRFSNPIKYLIGNLSNRKDLKRVNIQKAKLSVILSTPFTNKISEDDIDNIMTAMILKSQRKNMRTIVQLHLYSNKVLLKMSPMWNQNRSDIILCIDELKLGLMAYNCLTPGIATLVINLVTFTKSKSVSE-LWRKDYENGLKVLLYNVQFSDCFHGMSCLEVALIVYKLWDVCLLAIKCVNKSTDDYVLINPMIENIKIDTDSMIAIVMARDEASSNKLIFYCSKCSPQ--NQSEICQCYLEATKNSPRGHYESNLQFENQRINESFRSAYEF----PTIDSKSEEI---DINSYTGLDRTGSFYWAPEPNFEDVCLDIETAESRSLSDHILVCLCG-IGHGTIDLCNFMMPLRFQNLQNSELRTIVILGNKSYFEADKWTNIKNFPMFLIIDGSPIQSRDLRAAGLLKCHTCVIINGNDKTV---GFSDKSAIICATLIRSMRKLNKLKI----------PIMIEIRKDE-----IAHHFSSIHSHN--------NDSKV-------------SVQHSEPFARGILFTNSTVYSCIYTVYKNPDTFSFIKTLLNGRYSDEIESMFGSGVGL-----LPQXXXXXXXXXXXXIIKLFSVIQPPLNEISRVYDGILDYACLFEWALMEKRILCLGLYRLNFGR--------NRYVFTHPEKSTEIFSTDQVYCCVSSD 3055
            +MIS  T+ GR L  V  +  L+   + + F    ++++  I  C +        ID A NIF L +F LR  AAND L FW++  ++++   +P + ++ +L     G  FLR   L +    +     ILK ++  ++  +    IS WL +AG  H+ E  G+ W     +Q LS+W C Y ++VT+STVG+G V   T  GR+ ++ +I+ G+ MF   +P +   I N K Y   + +    +HI+VCG     ++  FLK F   + +  V NV+IV ++    +  L    KR    +++  G++ N  DL RV I+ A   +IL+  +      +D  NIM  + +K+    +R I Q+  Y NK  L   P WN    D  +C+ ELKLG +A +CL  G++T++ NL +      + E  W+K Y  G+   +Y    S  F G+S   V  + +    + ++AI+  ++  +  ++INP   ++KI  +  +   +A D     +  FYC  C     +   I +C  +  ++          +  N  + +S  S+       P + + +++I   D +S    D TG F+W P    + V L    A    LS H++VC+ G +    I + N +MPLR  N    EL+ IV +G+  Y + + W  + NFP   I+ G+P+   DLRA  +  C  CVI++ N   +      DK  I+ +  I+SM+  + + +          P M     D      +A   S     N        NDS V              +  ++PFA G  F  S + S +   Y N +  + I+TL+ G  + E+E++      L      PQ  ++ +R      +   ++   P  ++    DG   Y  L+  AL    +LC G+YRL             RYV T+P    E+  TD ++C +  D
Sbjct:  165 VMISAQTLTGRVL--VVTVFALSIGALMIYF----IDSSNPIETCQNFYKDFTLQIDMAFNIFFLLYFGLRFIAANDKLWFWLEVNSVVDFFTVPPVFVSVYLNRSWLGLRFLRALRLIQFSEILQF-LNILKTSNSIKLVNLCSIFISTWLTAAGFIHLVENSGDPWRNFENSQDLSYWECVYLLMVTMSTVGYGDVYAKTTLGRLFMVFFILGGLAMFARYVPEIAALILNRKKYGGTFNATRGRKHIVVCGHITLESVSNFLKDF-LHKDRDDV-NVEIVFLHNISPNLELEALFKRHFTQVEFYQGSVLNPHDLARVKIESADACLILANKYCADPDAEDASNIMRVISIKNYHPKIRIITQMLQYHNKAHLLNIPSWNWKEGDDAICLAELKLGFIAQSCLAQGLSTMLANLFSMRSFIKIEEDTWQKYYLEGVSNEMYTEYLSSAFVGLSFPAVCELCFVKLKLLMIAIEFKSEKGESRIIINPG-NHVKI-KEGTLGFFIASDAKEVKRAFFYCKACHDDITDPKRIKKCACKRLEDEQPSALSPKKKQRNGGMRQSPNSSPNMMRHDPLLMTGNDQIDNMDSSSVKRYDSTGMFHWCPAKELDKVLLTRSEAAMTVLSGHVVVCIFGDMTSALIGVRNLVMPLRASNFHYHELKHIVFVGSLDYLKRE-WETLHNFPKVSILPGTPLSRADLRAVNINLCDMCVILSANQNNIDDTSLQDKECILASLNIKSMQFDDSIGLLQANSQGFTPPGMERSSPDNSPVHGVARQASITTGANIPIITELVNDSNVQFLDQDDDDDPDTELYLTQPFACGTAFAVSVLDSLMSATYFNDNILTLIRTLVTGGATPELEALIAEENALRGGYSTPQTLANRDRCR----VAQLALYDGPFADLG---DGGC-YGDLYCKALKTYNMLCFGIYRLRDAHLSTPSQCTKRYVITNPPYEFELVPTDLIFCLMQFD 1119

[Close]

BLAST of Calcium-activated potassium channel subunit alpha-1 vs. Ensembl Xenopus
Match: KCNMA1 (potassium calcium-activated channel subfamily M alpha 1 [Source:NCBI gene;Acc:100491898])

HSP 1 Score: 330.872 bits (847), Expect = 4.879e-96
Identity = 265/976 (27.15%), Postives = 442/976 (45.29%), Query Frame = 2

Query:  323 IMISKSTIVGRFLNFVKLISQLTSWGIFVVFTFNQVNANYLIGDCFDVEGANLQWIDFALNIFCLFHFTLRAFAANDILKFWIQPTTMIEITVIPNILLTSFLPVRRQGFSFLRIYYLRELCNTIAVSFGILKVNSKFEMTKVIFYIISLWLISAGLFHMFEGIGNFWEIPLFNQQLSFWRCCYFMLVTISTVGFGSVNPLTIFGRIVVLVYIIYGITMFVTVLPNVIRTIQNL-KYKNRYISKGNERHIIVCGKFESLTIIAFLKAF-KRERFKGSVRNVKIVTMNKDLYDENLLMYMKRFSNPIKYLIGNLSNRKDLKRVNIQKAKLSVILSTPFTNKISEDDIDNIMTAMILKSQRKNMRTIVQLHLYSNKVLLKMSPMWNQNRSDIILCIDELKLGLMAYNCLTPGIATLVINLVTFTKSKSVSE-LWRKDYENGLKVLLYNVQFSDCFHGMSCLEVALIVYKLWDVCLLAIKCVNKSTDDYVLINPMIENIKIDTDSMIAIVMARDEASSNKLIFY---CSKCS----P--QNQSEICQCYLEATKNSPRGHYESNLQFENQRINESFRSAYEFPTIDSKSEEIDINSYTGLDRTGSFYWAPEPNFEDVCLDIETAESRSLSDHILVCLCG-IGHGTIDLCNFMMPLRFQNLQNSELRTIVILGNKSYFEADKWTNIKNFPMFLIIDGSPIQSRDLRAAGLLKCHTCVIINGNDKTV---GFSDKSAIICATLIRSMRKLNKLKI----------PIMIEIRKDE-----IAHHFSSIHSHN--------NDSKV-------------SVQHSEPFARGILFTNSTVYSCIYTVYKNPDTFSFIKTLLNGRYSDEIESMFGSGVGL-----LPQXXXXXXXXXXXXIIKLFSVIQPPLNEISRVYDGILDYACLFEWALMEKRILCLGLYRLNFGR--------NRYVFTHPEKSTEIFSTDQVYCCVSSD 3055
            +MIS  T+ GR L  V  +  L+   + + F    ++++  I  C +        ID A NIF L +F LR  AAND L FW++  ++++   +P + ++ +L     G  FLR   L +    +     ILK ++  ++  +    IS WL +AG  H+ E  G+ W     +Q LS+W C Y ++VT+STVG+G V   T  GR+ ++ +I+ G+ MF + +P +I  I N  KY   Y +    +HI+VCG     ++  FLK F  ++R      NV+IV ++    +  L    KR    +++  G++ N  DL RV I+ A   +IL+  +      +D  NIM  + +K+    +R I Q+  Y NK  L   P WN    D  +C+ ELKLG +A +CL  G++T++ NL +      + E  W+K Y  G+   +Y    S  F G+S   V  + +    + ++AI+  ++  +  ++INP   ++KI  +  +   +A D     + + +   C  C+    P       +C   L+ + +    +   N+           R      T + + + +D +S    D TG F+W P    + V L    A    LS H++VC+ G +    I + N +MPLR  N    EL+ IV +G+  Y + + W  + NFP   I+ G+P+   DLRA  +  C  CVI++ N   +      DK  I+ +  I+SM+  + + +          P M     D      +A   S     N        NDS V              +  ++PFA G  F  S + S +   Y N +  + I+TL+ G  + E+E++      L      PQ  ++ +R      +   ++   P  ++    DG   Y  L+  AL    +LC G+YRL             RYV T+P    E+  TD ++C +  D
Sbjct:  102 VMISAQTLTGRVL--VVTVFALSIGALMIYF----IDSSNPIETCQNFYKDFTLQIDMAFNIFFLLYFGLRFIAANDKLWFWLEVNSVVDFFTVPPVFVSVYLNRSWLGLRFLRALRLIQFSEILQF-LNILKTSNSIKLVNLCSIFISTWLTAAGFIHLVENSGDPWRNFENSQDLSYWECVYLLMVTMSTVGYGDVYAKTTLGRLFMVFFILGGLAMFASYVPEIIELIGNRKKYGGSYSAVSGRKHIVVCGHITLESVSNFLKDFLHKDR---DDVNVEIVFLHNISPNLELEALFKRHFTQVEFYQGSVLNPHDLARVKIESADACLILANKYCADPDAEDASNIMRVISIKNYHPKIRIITQMLQYHNKAHLLNIPSWNWKEGDDAICLAELKLGFIAQSCLAQGLSTMLANLFSMRSFIKIEEDTWQKYYLEGVSNEMYTEYLSSAFVGLSFPAVCELCFVKLKLLMIAIEFKSEKGESRIIINPG-NHVKI-KEGTLGFFIASDAKEVKRYVCFPVCCPVCTYSTLPVFHTLPTLCCLCLKMSNHQQSPNSSPNM----------MRHDPLLMTGNDQIDNMDSSSVKRYDSTGMFHWCPAKELDKVLLTRSEAAMTVLSGHVVVCIFGDMTSALIGVRNLVMPLRASNFHYHELKHIVFVGSLDYLKRE-WETLHNFPKVSILPGTPLSRADLRAVNINLCDMCVILSANQNNIDDTSLQDKECILASLNIKSMQFDDSIGLLQANSQGFTPPGMERSSPDNSPVHGVARQASITTGANIPIITELVNDSNVQFLDQDDDDDPDTELYLTQPFACGTAFAVSVLDSLMSATYFNDNILTLIRTLVTGGATPELEALIAEENALRGGYSTPQTLANRDRCR----VAQLALYDGPFADLG---DGGC-YGDLYCKALKTYNMLCFGIYRLRDAHLSTPSQCTKRYVITNPPYEFELVPTDLIFCLMQFD 1046

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BLAST of Calcium-activated potassium channel subunit alpha-1 vs. Ensembl Xenopus
Match: KCNMA1 (potassium calcium-activated channel subfamily M alpha 1 [Source:NCBI gene;Acc:100491898])

HSP 1 Score: 330.872 bits (847), Expect = 1.360e-95
Identity = 268/1000 (26.80%), Postives = 446/1000 (44.60%), Query Frame = 2

Query:  323 IMISKSTIVGRFLNFVKLISQLTSWGIFVVFTFNQVNANYLIGDCFDVEGANLQWIDFALNIFCLFHFTLRAFAANDILKFWIQPTTMIEITVIPNILLTSFLPVRRQGFSFLRIYYLRELCNTIAVSFGILKVNSKFEMTKVIFYIISLWLISAGLFHMFEGIGNFWEIPLFNQQLSFWRCCYFMLVTISTVGFGSVNPLTIFGRIVVLVYIIYGITMFVTVLPNVIRTIQNLK-YKNRYISKGNERHIIVCGKFESLTIIAFLKAF-KRERFKGSVRNVKIVTMNKDLYDENLLMYMKRFSNPIKYLIGNLSNRKDLKRVNIQKAKLSVILSTPFTNKISEDDIDNIMTAMILKSQRKNMRTIVQLHLYSNKVLLKMSPMWNQNRSDIILCIDELKLGLMAYNCLTPGIATLVINLVTFTKSKSVSE-LWRKDYENGLKVLLYNVQFSDCFHGMSCLEVALIVYKLWDVCLLAIKCVNKSTDDY------------------------VLINPMIENIKIDTDSMIAIVMARDEASSNKLIFYCSKCSPQ--NQSEICQCYLEATKNSPRGHYESNLQFENQRINESFRSAYEF----PTIDSKSEEID---INSYTGLDRTGSFYWAPEPNFEDVCLDIETAESRSLSDHILVCLCG-IGHGTIDLCNFMMPLRFQNLQNSELRTIVILGNKSYFEADKWTNIKNFPMFLIIDGSPIQSRDLRAAGLLKCHTCVIINGNDKTV---GFSDKSAIICATLIRSMRKLNKLKI----------PIMIEIRKDE-----IAHHFSSIHSHN--------NDSKV-------------SVQHSEPFARGILFTNSTVYSCIYTVYKNPDTFSFIKTLLNGRYSDEIESMFGSGVGL-----LPQXXXXXXXXXXXXIIKLFSVIQPPLNEISRVYDGILDYACLFEWALMEKRILCLGLYRLNFGR--------NRYVFTHPEKSTEIFSTDQVYCCVSSD 3055
            +MIS  T+ GR L  V  +  L+   + + F    ++++  I  C +        ID A NIF L +F LR  AAND L FW++  ++++   +P + ++ +L     G  FLR   L +    +     ILK ++  ++  +    IS WL +AG  H+ E  G+ W     +Q LS+W C Y ++VT+STVG+G V   T  GR+ ++ +I+ G+ MF + +P +I  I N K Y   Y +    +HI+VCG     ++  FLK F  ++R      NV+IV ++    +  L    KR    +++  G++ N  DL RV I+ A   +IL+  +      +D  NIM  + +K+    +R I Q+  Y NK  L   P WN    D  +C+ ELKLG +A +CL  G++T++ NL +      + E  W+K Y  G+   +Y    S  F G+S   V  + +    + ++AI+  ++  +                          ++INP   ++KI  +  +   +A D     +  FYC  C     +   I +C  +  ++          +  N  + +S  S+       P + + +++ID    +S    D TG F+W P    + V L    A    LS H++VC+ G +    I + N +MPLR  N    EL+ IV +G+  Y + + W  + NFP   I+ G+P+   DLRA  +  C  CVI++ N   +      DK  I+ +  I+SM+  + + +          P M     D      +A   S     N        NDS V              +  ++PFA G  F  S + S +   Y N +  + I+TL+ G  + E+E++      L      PQ  ++ +R      +   ++   P  ++    DG   Y  L+  AL    +LC G+YRL             RYV T+P    E+  TD ++C +  D
Sbjct:  102 VMISAQTLTGRVL--VVTVFALSIGALMIYF----IDSSNPIETCQNFYKDFTLQIDMAFNIFFLLYFGLRFIAANDKLWFWLEVNSVVDFFTVPPVFVSVYLNRSWLGLRFLRALRLIQFSEILQF-LNILKTSNSIKLVNLCSIFISTWLTAAGFIHLVENSGDPWRNFENSQDLSYWECVYLLMVTMSTVGYGDVYAKTTLGRLFMVFFILGGLAMFASYVPEIIELIGNRKKYGGSYSAVSGRKHIVVCGHITLESVSNFLKDFLHKDR---DDVNVEIVFLHNISPNLELEALFKRHFTQVEFYQGSVLNPHDLARVKIESADACLILANKYCADPDAEDASNIMRVISIKNYHPKIRIITQMLQYHNKAHLLNIPSWNWKEGDDAICLAELKLGFIAQSCLAQGLSTMLANLFSMRSFIKIEEDTWQKYYLEGVSNEMYTEYLSSAFVGLSFPAVCELCFVKLKLLMIAIEFKSEKGESRGSKLEAVDILARFCVITFRVFFTRIIINPG-NHVKI-KEGTLGFFIASDAKEVKRAFFYCKACHDDITDPKRIKKCACKRLEDEQPSALSPKKKQRNGGMRQSPNSSPNMMRHDPLLMTGNDQIDNMDSSSVKRYDSTGMFHWCPAKELDKVLLTRSEAAMTVLSGHVVVCIFGDMTSALIGVRNLVMPLRASNFHYHELKHIVFVGSLDYLKRE-WETLHNFPKVSILPGTPLSRADLRAVNINLCDMCVILSANQNNIDDTSLQDKECILASLNIKSMQFDDSIGLLQANSQGFTPPGMERSSPDNSPVHGVARQASITTGANIPIITELVNDSNVQFLDQDDDDDPDTELYLTQPFACGTAFAVSVLDSLMSATYFNDNILTLIRTLVTGGATPELEALIAEENALRGGYSTPQTLANRDRCR----VAQLALYDGPFADLG---DGGC-YGDLYCKALKTYNMLCFGIYRLRDAHLSTPSQCTKRYVITNPPYEFELVPTDLIFCLMQFD 1080

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BLAST of Calcium-activated potassium channel subunit alpha-1 vs. Ensembl Mouse
Match: Kcnma1 (potassium large conductance calcium-activated channel, subfamily M, alpha member 1 [Source:MGI Symbol;Acc:MGI:99923])

HSP 1 Score: 349.747 bits (896), Expect = 4.663e-103
Identity = 272/974 (27.93%), Postives = 447/974 (45.89%), Query Frame = 2

Query:  323 IMISKSTIVGRFLNFVKLISQLTSWGIFVVFTFNQVNANYLIGDCFDVEGANLQWIDFALNIFCLFHFTLRAFAANDILKFWIQPTTMIEITVIPNILLTSFLPVRRQGFSFLRIYYLRELCNTIAVSFGILKVNSKFEMTKVIFYIISLWLISAGLFHMFEGIGNFWEIPLFNQQLSFWRCCYFMLVTISTVGFGSVNPLTIFGRIVVLVYIIYGITMFVTVLPNVIRTIQNLK-YKNRYISKGNERHIIVCGKFESLTIIAFLKAFKRERFKGSVRNVKIVTMNKDLYDENLLMYMKRFSNPIKYLIGNLSNRKDLKRVNIQKAKLSVILSTPFTNKISEDDIDNIMTAMILKSQRKNMRTIVQLHLYSNKVLLKMSPMWNQNRSDIILCIDELKLGLMAYNCLTPGIATLVINLVTFTKSKSVSE-LWRKDYENGLKVLLYNVQFSDCFHGMSCLEVALIVYKLWDVCLLAIKCVNKSTDDYVLINPMIENIKIDTDSMIAIVMARDEASSNKLIFYCSKC----SPQNQSEICQCYLEATKNSPRGHYESNLQFENQR--INESFRSAYEFPTIDSKSEEID--INSYTGLDRTGSFYWAPEPNFEDVCLDIETAESRSLSDHILVCLCG-IGHGTIDLCNFMMPLRFQNLQNSELRTIVILGNKSYFEADKWTNIKNFPMFLIIDGSPIQSRDLRAAGLLKCHTCVIINGNDKTV---GFSDKSAIICATLIRSMRKLNKLKI---------------------PIMIEIRKDEIAH--HFSSIHSHNNDSKV-------------SVQHSEPFARGILFTNSTVYSCIYTVYKNPDTFSFIKTLLNGRYSDEIESMFGSGVGL-----LPQXXXXXXXXXXXXIIKLFSVIQPPLNEISRVYDGILDYACLFEWALMEKRILCLGLYRLNFGR--------NRYVFTHPEKSTEIFSTDQVYCCVSSD 3055
            +MIS  T+ GR L  V L+  L S G  V++  +  N    I  C +        ID A N+F L +F LR  AAND L FW++  ++++   +P + ++ +L     G  FLR   L +    +     ILK ++  ++  ++   IS WL +AG  H+ E  G+ WE    NQ L++W C Y ++VT+STVG+G V   T  GR+ ++ +I+ G+ MF + +P +I  I N K Y   Y +    +HI+VCG     ++  FLK F  +  +  V NV+IV ++    +  L    KR    +++  G++ N  DL RV I+ A   +IL+  +      +D  NIM  + +K+    +R I Q+  Y NK  L   P WN    D  +C+ ELKLG +A +CL  G++T++ NL +      + E  W+K Y  G+   +Y    S  F G+S   V  + +    + ++AI+  + + +  +LINP   ++KI  +  +   +A D     +  FYC  C    +   + + C C     +  P    +   +    R   N S +     P +   +++ID   ++    D TG F+W      E V L    A    LS H++VC+ G +    I L N +MPLR  N    EL+ IV +G+  Y + + W  + NFP   I+ G+P+   DLRA  +  C  CVI++ N   +      DK  I+ +  I+SM+  + + +                     P+   +R+  I    +   I    ND+ V              +  ++PFA G  F  S + S +   Y N +  + I+TL+ G  + E+E++      L      PQ  ++ +R      +   +++  P  ++    DG   Y  LF  AL    +LC G+YRL             RYV T+P    E+  TD ++C +  D
Sbjct:  103 VMISAQTLTGRVL--VVLVFAL-SIGALVIYFIDSSNP---IESCQNFYKDFTLQIDMAFNVFFLLYFGLRFIAANDKLWFWLEVNSVVDFFTVPPVFVSVYLNRSWLGLRFLRALRLIQFSEILQF-LNILKTSNSIKLVNLLSIFISTWLTAAGFIHLVENSGDPWENFQNNQALTYWECVYLLMVTMSTVGYGDVYAKTTLGRLFMVFFILGGLAMFASYVPEIIELIGNRKKYGGSYSAVSGRKHIVVCGHITLESVSNFLKDFLHKD-RDDV-NVEIVFLHNISPNLELEALFKRHFTQVEFYQGSVLNPHDLARVKIESADACLILANKYCADPDAEDASNIMRVISIKNYHPKIRIITQMLQYHNKAHLLNIPSWNWKEGDDAICLAELKLGFIAQSCLAQGLSTMLANLFSMRSFIKIEEDTWQKYYLEGVSNEMYTEYLSSAFVGLSFPTVCELCFVKLKLLMIAIEYKSANRESRILINPG-NHLKIQ-EGTLGFFIASDAKEVKRAFFYCKACHDDVTDPKRIKKCGCRRLEDEQPPTLSPKKKQRNGGMRNSPNTSPKLMRHDPLLIPGNDQIDNMDSNVKKYDSTGMFHWCAPKEIEKVILTRSEAAMTVLSGHVVVCIFGDVSSALIGLRNLVMPLRASNFHYHELKHIVFVGSIEYLKRE-WETLHNFPKVSILPGTPLSRADLRAVNINLCDMCVILSANQNNIDDTSLQDKECILASLNIKSMQFDDSIGVLQANSQGFTPPGMDRSSPDNSPVHGMLRQPSITTGVNIPIITELVNDTNVQFLDQDDDDDPDTELYLTQPFACGTAFAVSVLDSLMSATYFNDNILTLIRTLVTGGATPELEALIAEENALRGGYSTPQTLANRDRCR----VAQLALLDGPFADLG---DGGC-YGDLFCKALKTYNMLCFGIYRLRDAHLSTPSQCTKRYVITNPPYEFELVPTDLIFCLMQFD 1056

[Close]

BLAST of Calcium-activated potassium channel subunit alpha-1 vs. Ensembl Mouse
Match: Kcnma1 (potassium large conductance calcium-activated channel, subfamily M, alpha member 1 [Source:MGI Symbol;Acc:MGI:99923])

HSP 1 Score: 349.747 bits (896), Expect = 5.442e-103
Identity = 272/975 (27.90%), Postives = 447/975 (45.85%), Query Frame = 2

Query:  323 IMISKSTIVGRFLNFVKLISQLTSWGIFVVFTFNQVNANYLIGDCFDVEGANLQWIDFALNIFCLFHFTLRAFAANDILKFWIQPTTMIEITVIPNILLTSFLPVRRQGFSFLRIYYLRELCNTIAVSFGILKVNSKFEMTKVIFYIISLWLISAGLFHMFEGIGNFWEIPLFNQQLSFWRCCYFMLVTISTVGFGSVNPLTIFGRIVVLVYIIYGITMFVTVLPNVIRTIQNLK-YKNRYISKGNERHIIVCGKFESLTIIAFLKAF-KRERFKGSVRNVKIVTMNKDLYDENLLMYMKRFSNPIKYLIGNLSNRKDLKRVNIQKAKLSVILSTPFTNKISEDDIDNIMTAMILKSQRKNMRTIVQLHLYSNKVLLKMSPMWNQNRSDIILCIDELKLGLMAYNCLTPGIATLVINLVTFTKSKSVSE-LWRKDYENGLKVLLYNVQFSDCFHGMSCLEVALIVYKLWDVCLLAIKCVNKSTDDYVLINPMIENIKIDTDSMIAIVMARDEASSNKLIFYCSKC----SPQNQSEICQCYLEATKNSPRGHYESNLQFENQR--INESFRSAYEFPTIDSKSEEID--INSYTGLDRTGSFYWAPEPNFEDVCLDIETAESRSLSDHILVCLCG-IGHGTIDLCNFMMPLRFQNLQNSELRTIVILGNKSYFEADKWTNIKNFPMFLIIDGSPIQSRDLRAAGLLKCHTCVIINGNDKTV---GFSDKSAIICATLIRSMRKLNKLKI---------------------PIMIEIRKDEIAH--HFSSIHSHNNDSKVS-------------VQHSEPFARGILFTNSTVYSCIYTVYKNPDTFSFIKTLLNGRYSDEIESMFGSGVGL-----LPQXXXXXXXXXXXXIIKLFSVIQPPLNEISRVYDGILDYACLFEWALMEKRILCLGLYRLNFGR--------NRYVFTHPEKSTEIFSTDQVYCCVSSD 3055
            +MIS  T+ GR L  V L+  L S G  V++  +  N    I  C +        ID A N+F L +F LR  AAND L FW++  ++++   +P + ++ +L     G  FLR   L +    +     ILK ++  ++  ++   IS WL +AG  H+ E  G+ WE    NQ L++W C Y ++VT+STVG+G V   T  GR+ ++ +I+ G+ MF + +P +I  I N K Y   Y +    +HI+VCG     ++  FLK F  ++R      NV+IV ++    +  L    KR    +++  G++ N  DL RV I+ A   +IL+  +      +D  NIM  + +K+    +R I Q+  Y NK  L   P WN    D  +C+ ELKLG +A +CL  G++T++ NL +      + E  W+K Y  G+   +Y    S  F G+S   V  + +    + ++AI+  + + +  +LINP   ++KI  +  +   +A D     +  FYC  C    +   + + C C     +  P    +   +    R   N S +     P +   +++ID   ++    D TG F+W      E V L    A    LS H++VC+ G +    I L N +MPLR  N    EL+ IV +G+  Y + + W  + NFP   I+ G+P+   DLRA  +  C  CVI++ N   +      DK  I+ +  I+SM+  + + +                     P+   +R+  I    +   I    ND+ V              +  ++PFA G  F  S + S +   Y N +  + I+TL+ G  + E+E++      L      PQ  ++ +R      +   +++  P  ++    DG   Y  LF  AL    +LC G+YRL             RYV T+P    E+  TD ++C +  D
Sbjct:  103 VMISAQTLTGRVL--VVLVFAL-SIGALVIYFIDSSNP---IESCQNFYKDFTLQIDMAFNVFFLLYFGLRFIAANDKLWFWLEVNSVVDFFTVPPVFVSVYLNRSWLGLRFLRALRLIQFSEILQF-LNILKTSNSIKLVNLLSIFISTWLTAAGFIHLVENSGDPWENFQNNQALTYWECVYLLMVTMSTVGYGDVYAKTTLGRLFMVFFILGGLAMFASYVPEIIELIGNRKKYGGSYSAVSGRKHIVVCGHITLESVSNFLKDFLHKDR---DDVNVEIVFLHNISPNLELEALFKRHFTQVEFYQGSVLNPHDLARVKIESADACLILANKYCADPDAEDASNIMRVISIKNYHPKIRIITQMLQYHNKAHLLNIPSWNWKEGDDAICLAELKLGFIAQSCLAQGLSTMLANLFSMRSFIKIEEDTWQKYYLEGVSNEMYTEYLSSAFVGLSFPTVCELCFVKLKLLMIAIEYKSANRESRILINPG-NHLKIQ-EGTLGFFIASDAKEVKRAFFYCKACHDDVTDPKRIKKCGCRRLEDEQPPTLSPKKKQRNGGMRNSPNTSPKLMRHDPLLIPGNDQIDNMDSNVKKYDSTGMFHWCAPKEIEKVILTRSEAAMTVLSGHVVVCIFGDVSSALIGLRNLVMPLRASNFHYHELKHIVFVGSIEYLKRE-WETLHNFPKVSILPGTPLSRADLRAVNINLCDMCVILSANQNNIDDTSLQDKECILASLNIKSMQFDDSIGVLQANSQGFTPPGMDRSSPDNSPVHGMLRQPSITTGVNIPIITELVNDTNVQFLDQDDDDDPDTELYLTQPFACGTAFAVSVLDSLMSATYFNDNILTLIRTLVTGGATPELEALIAEENALRGGYSTPQTLANRDRCR----VAQLALLDGPFADLG---DGGC-YGDLFCKALKTYNMLCFGIYRLRDAHLSTPSQCTKRYVITNPPYEFELVPTDLIFCLMQFD 1056

[Close]

BLAST of Calcium-activated potassium channel subunit alpha-1 vs. Ensembl Mouse
Match: Kcnma1 (potassium large conductance calcium-activated channel, subfamily M, alpha member 1 [Source:MGI Symbol;Acc:MGI:99923])

HSP 1 Score: 348.977 bits (894), Expect = 2.831e-102
Identity = 272/975 (27.90%), Postives = 447/975 (45.85%), Query Frame = 2

Query:  323 IMISKSTIVGRFLNFVKLISQLTSWGIFVVFTFNQVNANYLIGDCFDVEGANLQWIDFALNIFCLFHFTLRAFAANDILKFWIQPTTMIEITVIPNILLTSFLPVRRQGFSFLRIYYLRELCNTIAVSFGILKVNSKFEMTKVIFYIISLWLISAGLFHMFEGIGNFWEIPLFNQQLSFWRCCYFMLVTISTVGFGSVNPLTIFGRIVVLVYIIYGITMFVTVLPNVIRTIQNLK-YKNRYISKGNERHIIVCGKFESLTIIAFLKAF-KRERFKGSVRNVKIVTMNKDLYDENLLMYMKRFSNPIKYLIGNLSNRKDLKRVNIQKAKLSVILSTPFTNKISEDDIDNIMTAMILKSQRKNMRTIVQLHLYSNKVLLKMSPMWNQNRSDIILCIDELKLGLMAYNCLTPGIATLVINLVTFTKSKSVSE-LWRKDYENGLKVLLYNVQFSDCFHGMSCLEVALIVYKLWDVCLLAIKCVNKSTDDYVLINPMIENIKIDTDSMIAIVMARDEASSNKLIFYCSKC----SPQNQSEICQCYLEATKNSPRGHYESNLQFENQR--INESFRSAYEFPTIDSKSEEID--INSYTGLDRTGSFYWAPEPNFEDVCLDIETAESRSLSDHILVCLCG-IGHGTIDLCNFMMPLRFQNLQNSELRTIVILGNKSYFEADKWTNIKNFPMFLIIDGSPIQSRDLRAAGLLKCHTCVIINGNDKTV---GFSDKSAIICATLIRSMRKLNKLKI---------------------PIMIEIRKDEIAH--HFSSIHSHNNDSKVS-------------VQHSEPFARGILFTNSTVYSCIYTVYKNPDTFSFIKTLLNGRYSDEIESMFGSGVGL-----LPQXXXXXXXXXXXXIIKLFSVIQPPLNEISRVYDGILDYACLFEWALMEKRILCLGLYRLNFGR--------NRYVFTHPEKSTEIFSTDQVYCCVSSD 3055
            +MIS  T+ GR L  V L+  L S G  V++  +  N    I  C +        ID A N+F L +F LR  AAND L FW++  ++++   +P + ++ +L     G  FLR   L +    +     ILK ++  ++  ++   IS WL +AG  H+ E  G+ WE    NQ L++W C Y ++VT+STVG+G V   T  GR+ ++ +I+ G+ MF + +P +I  I N K Y   Y +    +HI+VCG     ++  FLK F  ++R      NV+IV ++    +  L    KR    +++  G++ N  DL RV I+ A   +IL+  +      +D  NIM  + +K+    +R I Q+  Y NK  L   P WN    D  +C+ ELKLG +A +CL  G++T++ NL +      + E  W+K Y  G+   +Y    S  F G+S   V  + +    + ++AI+  + + +  +LINP   ++KI  +  +   +A D     +  FYC  C    +   + + C C     +  P    +   +    R   N S +     P +   +++ID   ++    D TG F+W      E V L    A    LS H++VC+ G +    I L N +MPLR  N    EL+ IV +G+  Y + + W  + NFP   I+ G+P+   DLRA  +  C  CVI++ N   +      DK  I+ +  I+SM+  + + +                     P+   +R+  I    +   I    ND+ V              +  ++PFA G  F  S + S +   Y N +  + I+TL+ G  + E+E++      L      PQ  ++ +R      +   +++  P  ++    DG   Y  LF  AL    +LC G+YRL             RYV T+P    E+  TD ++C +  D
Sbjct:  168 VMISAQTLTGRVL--VVLVFAL-SIGALVIYFIDSSNP---IESCQNFYKDFTLQIDMAFNVFFLLYFGLRFIAANDKLWFWLEVNSVVDFFTVPPVFVSVYLNRSWLGLRFLRALRLIQFSEILQF-LNILKTSNSIKLVNLLSIFISTWLTAAGFIHLVENSGDPWENFQNNQALTYWECVYLLMVTMSTVGYGDVYAKTTLGRLFMVFFILGGLAMFASYVPEIIELIGNRKKYGGSYSAVSGRKHIVVCGHITLESVSNFLKDFLHKDR---DDVNVEIVFLHNISPNLELEALFKRHFTQVEFYQGSVLNPHDLARVKIESADACLILANKYCADPDAEDASNIMRVISIKNYHPKIRIITQMLQYHNKAHLLNIPSWNWKEGDDAICLAELKLGFIAQSCLAQGLSTMLANLFSMRSFIKIEEDTWQKYYLEGVSNEMYTEYLSSAFVGLSFPTVCELCFVKLKLLMIAIEYKSANRESRILINPG-NHLKIQ-EGTLGFFIASDAKEVKRAFFYCKACHDDVTDPKRIKKCGCRRLEDEQPPTLSPKKKQRNGGMRNSPNTSPKLMRHDPLLIPGNDQIDNMDSNVKKYDSTGMFHWCAPKEIEKVILTRSEAAMTVLSGHVVVCIFGDVSSALIGLRNLVMPLRASNFHYHELKHIVFVGSIEYLKRE-WETLHNFPKVSILPGTPLSRADLRAVNINLCDMCVILSANQNNIDDTSLQDKECILASLNIKSMQFDDSIGVLQANSQGFTPPGMDRSSPDNSPVHGMLRQPSITTGVNIPIITELVNDTNVQFLDQDDDDDPDTELYLTQPFACGTAFAVSVLDSLMSATYFNDNILTLIRTLVTGGATPELEALIAEENALRGGYSTPQTLANRDRCR----VAQLALLDGPFADLG---DGGC-YGDLFCKALKTYNMLCFGIYRLRDAHLSTPSQCTKRYVITNPPYEFELVPTDLIFCLMQFD 1121

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BLAST of Calcium-activated potassium channel subunit alpha-1 vs. Ensembl Mouse
Match: Kcnma1 (potassium large conductance calcium-activated channel, subfamily M, alpha member 1 [Source:MGI Symbol;Acc:MGI:99923])

HSP 1 Score: 348.591 bits (893), Expect = 3.232e-102
Identity = 272/974 (27.93%), Postives = 447/974 (45.89%), Query Frame = 2

Query:  323 IMISKSTIVGRFLNFVKLISQLTSWGIFVVFTFNQVNANYLIGDCFDVEGANLQWIDFALNIFCLFHFTLRAFAANDILKFWIQPTTMIEITVIPNILLTSFLPVRRQGFSFLRIYYLRELCNTIAVSFGILKVNSKFEMTKVIFYIISLWLISAGLFHMFEGIGNFWEIPLFNQQLSFWRCCYFMLVTISTVGFGSVNPLTIFGRIVVLVYIIYGITMFVTVLPNVIRTIQNLK-YKNRYISKGNERHIIVCGKFESLTIIAFLKAFKRERFKGSVRNVKIVTMNKDLYDENLLMYMKRFSNPIKYLIGNLSNRKDLKRVNIQKAKLSVILSTPFTNKISEDDIDNIMTAMILKSQRKNMRTIVQLHLYSNKVLLKMSPMWNQNRSDIILCIDELKLGLMAYNCLTPGIATLVINLVTFTKSKSVSE-LWRKDYENGLKVLLYNVQFSDCFHGMSCLEVALIVYKLWDVCLLAIKCVNKSTDDYVLINPMIENIKIDTDSMIAIVMARDEASSNKLIFYCSKC----SPQNQSEICQCYLEATKNSPRGHYESNLQFENQR--INESFRSAYEFPTIDSKSEEID--INSYTGLDRTGSFYWAPEPNFEDVCLDIETAESRSLSDHILVCLCG-IGHGTIDLCNFMMPLRFQNLQNSELRTIVILGNKSYFEADKWTNIKNFPMFLIIDGSPIQSRDLRAAGLLKCHTCVIINGNDKTV---GFSDKSAIICATLIRSMRKLNKLKI---------------------PIMIEIRKDEIAH--HFSSIHSHNNDSKVS-------------VQHSEPFARGILFTNSTVYSCIYTVYKNPDTFSFIKTLLNGRYSDEIESMFGSGVGL-----LPQXXXXXXXXXXXXIIKLFSVIQPPLNEISRVYDGILDYACLFEWALMEKRILCLGLYRLNFGR--------NRYVFTHPEKSTEIFSTDQVYCCVSSD 3055
            +MIS  T+ GR L  V L+  L S G  V++  +  N    I  C +        ID A N+F L +F LR  AAND L FW++  ++++   +P + ++ +L     G  FLR   L +    +     ILK ++  ++  ++   IS WL +AG  H+ E  G+ WE    NQ L++W C Y ++VT+STVG+G V   T  GR+ ++ +I+ G+ MF + +P +I  I N K Y   Y +    +HI+VCG     ++  FLK F   + +  V NV+IV ++    +  L    KR    +++  G++ N  DL RV I+ A   +IL+  +      +D  NIM  + +K+    +R I Q+  Y NK  L   P WN    D  +C+ ELKLG +A +CL  G++T++ NL +      + E  W+K Y  G+   +Y    S  F G+S   V  + +    + ++AI+  + + +  +LINP   ++KI  +  +   +A D     +  FYC  C    +   + + C C     +  P    +   +    R   N S +     P +   +++ID   ++    D TG F+W      E V L    A    LS H++VC+ G +    I L N +MPLR  N    EL+ IV +G+  Y + + W  + NFP   I+ G+P+   DLRA  +  C  CVI++ N   +      DK  I+ +  I+SM+  + + +                     P+   +R+  I    +   I    ND+ V              +  ++PFA G  F  S + S +   Y N +  + I+TL+ G  + E+E++      L      PQ  ++ +R      +   +++  P  ++    DG   Y  LF  AL    +LC G+YRL             RYV T+P    E+  TD ++C +  D
Sbjct:  103 VMISAQTLTGRVL--VVLVFAL-SIGALVIYFIDSSNP---IESCQNFYKDFTLQIDMAFNVFFLLYFGLRFIAANDKLWFWLEVNSVVDFFTVPPVFVSVYLNRSWLGLRFLRALRLIQFSEILQF-LNILKTSNSIKLVNLLSIFISTWLTAAGFIHLVENSGDPWENFQNNQALTYWECVYLLMVTMSTVGYGDVYAKTTLGRLFMVFFILGGLAMFASYVPEIIELIGNRKKYGGSYSAVSGRKHIVVCGHITLESVSNFLKDF-LHKDRDDV-NVEIVFLHNISPNLELEALFKRHFTQVEFYQGSVLNPHDLARVKIESADACLILANKYCADPDAEDASNIMRVISIKNYHPKIRIITQMLQYHNKAHLLNIPSWNWKEGDDAICLAELKLGFIAQSCLAQGLSTMLANLFSMRSFIKIEEDTWQKYYLEGVSNEMYTEYLSSAFVGLSFPTVCELCFVKLKLLMIAIEYKSANRESRILINPG-NHLKIQ-EGTLGFFIASDAKEVKRAFFYCKACHDDVTDPKRIKKCGCRRLEDEQPPTLSPKKKQRNGGMRNSPNTSPKLMRHDPLLIPGNDQIDNMDSNVKKYDSTGMFHWCAPKEIEKVILTRSEAAMTVLSGHVVVCIFGDVSSALIGLRNLVMPLRASNFHYHELKHIVFVGSIEYLKRE-WETLHNFPKVSILPGTPLSRADLRAVNINLCDMCVILSANQNNIDDTSLQDKECILASLNIKSMQFDDSIGVLQANSQGFTPPGMDRSSPDNSPVHGMLRQPSITTGVNIPIITELVNDTNVQFLDQDDDDDPDTELYLTQPFACGTAFAVSVLDSLMSATYFNDNILTLIRTLVTGGATPELEALIAEENALRGGYSTPQTLANRDRCR----VAQLALLDGPFADLG---DGGC-YGDLFCKALKTYNMLCFGIYRLRDAHLSTPSQCTKRYVITNPPYEFELVPTDLIFCLMQFD 1056

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BLAST of Calcium-activated potassium channel subunit alpha-1 vs. Ensembl Mouse
Match: Kcnma1 (potassium large conductance calcium-activated channel, subfamily M, alpha member 1 [Source:MGI Symbol;Acc:MGI:99923])

HSP 1 Score: 347.436 bits (890), Expect = 3.640e-102
Identity = 276/979 (28.19%), Postives = 452/979 (46.17%), Query Frame = 2

Query:  323 IMISKSTIVGRFLNFVKLISQLTSWGIFVVFTFNQVNANYLIGDCFDVEGANLQWIDFALNIFCLFHFTLRAFAANDILKFWIQPTTMIEITVIPNILLTSFLPVRRQGFSFLRIYYLRELCNTIAVSFGILKVNSKFEMTKVIFYIISLWLISAGLFHMFEGIGNFWEIPLFNQQLSFWRCCYFMLVTISTVGFGSVNPLTIFGRIVVLVYIIYGITMFVTVLPNVIRTIQNLK-YKNRYISKGNERHIIVCGKFESLTIIAFLKAFKRERFKGSVRNVKIVTMNKDLYDENLLMYMKRFSNPIKYLIGNLSNRKDLKRVNIQKAKLSVILSTPFTNKISEDDIDNIMTAMILKSQRKNMRTIVQLHLYSNKVLLKMSPMWNQNRSDIILCIDELKLGLMAYNCLTPGIATLVINLVTFTKSKSVSE-LWRKDYENGLKVLLYNVQFSDCFHGMSCLEVALIVYKLWDVCLLAIKCVNKSTDDYVLINPMIENIKIDTDSMIAIVMARDEASSNKLIFYCSKC----SPQNQSEICQC----YLEATKN---SPRGHYESNLQFENQRINESFRSAYEFPTIDSKSEEID--INSYTGLDRTGSFYWAPEPNFEDVCLDIETAESRSLSDHILVCLCG-IGHGTIDLCNFMMPLRFQNLQNSELRTIVILGNKSYFEADKWTNIKNFPMFLIIDGSPIQSRDLRAAGLLKCHTCVIINGNDKTV---GFSDKSAIICATLIRSMRKLNKLKI---------------------PIMIEIRKDEIAH--HFSSIHSHNNDSKVS-------------VQHSEPFARGILFTNSTVYSCIYTVYKNPDTFSFIKTLLNGRYSDEIESMFGSGVGL-----LPQXXXXXXXXXXXXIIKLFSVIQPPLNEISRVYDGILDYACLFEWALMEKRILCLGLYRLNFGR--------NRYVFTHPEKSTEIFSTDQVYCCVSSD 3055
            +MIS  T+ GR L  V L+  L S G  V++  +  N    I  C +        ID A N+F L +F LR  AAND L FW++  ++++   +P + ++ +L     G  FLR   L +    +     ILK ++  ++  ++   IS WL +AG  H+ E  G+ WE    NQ L++W C Y ++VT+STVG+G V   T  GR+ ++ +I+ G+ MF + +P +I  I N K Y   Y +    +HI+VCG     ++  FLK F   + +  V NV+IV ++    +  L    KR    +++  G++ N  DL RV I+ A   +IL+  +      +D  NIM  + +K+    +R I Q+  Y NK  L   P WN    D  +C+ ELKLG +A +CL  G++T++ NL +      + E  W+K Y  G+   +Y    S  F G+S   V  + +    + ++AI+  + + +  +LINP   ++KI  +  +   +A D     +  FYC  C    +   + + C C    Y+E  +    SP+   + N    N   N S +     P +   +++ID   ++    D TG F+W      E V L    A    LS H++VC+ G +    I L N +MPLR  N    EL+ IV +G+  Y + + W  + NFP   I+ G+P+   DLRA  +  C  CVI++ N   +      DK  I+ +  I+SM+  + + +                     P+   +R+  I    +   I    ND+ V              +  ++PFA G  F  S + S +   Y N +  + I+TL+ G  + E+E++      L      PQ  ++ +R      +   +++  P  ++    DG   Y  LF  AL    +LC G+YRL             RYV T+P    E+  TD ++C +  D
Sbjct:   43 VMISAQTLTGRVL--VVLVFAL-SIGALVIYFIDSSNP---IESCQNFYKDFTLQIDMAFNVFFLLYFGLRFIAANDKLWFWLEVNSVVDFFTVPPVFVSVYLNRSWLGLRFLRALRLIQFSEILQF-LNILKTSNSIKLVNLLSIFISTWLTAAGFIHLVENSGDPWENFQNNQALTYWECVYLLMVTMSTVGYGDVYAKTTLGRLFMVFFILGGLAMFASYVPEIIELIGNRKKYGGSYSAVSGRKHIVVCGHITLESVSNFLKDF-LHKDRDDV-NVEIVFLHNISPNLELEALFKRHFTQVEFYQGSVLNPHDLARVKIESADACLILANKYCADPDAEDASNIMRVISIKNYHPKIRIITQMLQYHNKAHLLNIPSWNWKEGDDAICLAELKLGFIAQSCLAQGLSTMLANLFSMRSFIKIEEDTWQKYYLEGVSNEMYTEYLSSAFVGLSFPTVCELCFVKLKLLMIAIEYKSANRESRILINPG-NHLKIQ-EGTLGFFIASDAKEVKRAFFYCKACHDDVTDPKRIKKCGCRRPVYVEDEQPPTLSPKKK-QRNGGMRNSP-NTSPKLMRHDPLLIPGNDQIDNMDSNVKKYDSTGMFHWCAPKEIEKVILTRSEAAMTVLSGHVVVCIFGDVSSALIGLRNLVMPLRASNFHYHELKHIVFVGSIEYLKRE-WETLHNFPKVSILPGTPLSRADLRAVNINLCDMCVILSANQNNIDDTSLQDKECILASLNIKSMQFDDSIGVLQANSQGFTPPGMDRSSPDNSPVHGMLRQPSITTGVNIPIITELVNDTNVQFLDQDDDDDPDTELYLTQPFACGTAFAVSVLDSLMSATYFNDNILTLIRTLVTGGATPELEALIAEENALRGGYSTPQTLANRDRCR----VAQLALLDGPFADLG---DGGC-YGDLFCKALKTYNMLCFGIYRLRDAHLSTPSQCTKRYVITNPPYEFELVPTDLIFCLMQFD 999

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BLAST of Calcium-activated potassium channel subunit alpha-1 vs. UniProt/SwissProt
Match: sp|Q8AYS8|KCMA1_CHICK (Calcium-activated potassium channel subunit alpha-1 OS=Gallus gallus OX=9031 GN=KCNMA1 PE=1 SV=2)

HSP 1 Score: 362.844 bits (930), Expect = 9.218e-107
Identity = 278/978 (28.43%), Postives = 450/978 (46.01%), Query Frame = 2

Query:  323 IMISKSTIVGRFLNFVKLISQLTSWGIFVVFTFNQVNANYLIGDCFDVEGANLQWIDFALNIFCLFHFTLRAFAANDILKFWIQPTTMIEITVIPNILLTSFLPVRRQGFSFLRIYYLRELCNTIAVSFGILKVNSKFEMTKVIFYIISLWLISAGLFHMFEGIGNFWEIPLFNQQLSFWRCCYFMLVTISTVGFGSVNPLTIFGRIVVLVYIIYGITMFVTVLPNVIRTIQNL-KYKNRYISKGNERHIIVCGKFESLTIIAFLKAF-KRERFKGSVRNVKIVTMNKDLYDENLLMYMKRFSNPIKYLIGNLSNRKDLKRVNIQKAKLSVILSTPFTNKISEDDIDNIMTAMILKSQRKNMRTIVQLHLYSNKVLLKMSPMWNQNRSDIILCIDELKLGLMAYNCLTPGIATLVINLVTFTKSKSVSE-LWRKDYENGLKVLLYNVQFSDCFHGMSCLEVALIVYKLWDVCLLAIKCVNKSTDDYVLINPMIENIKIDTDSMIAIVMARDEASSNKLIFYCSKCSPQ--NQSEICQCYLEATKNSPRGHYESNLQFENQRINESFRSAYEF----PTIDSKSEEID-----INSYTGLDRTGSFYWAPEPNFEDVCLDIETAESRSLSDHILVCLCG-IGHGTIDLCNFMMPLRFQNLQNSELRTIVILGNKSYFEADKWTNIKNFPMFLIIDGSPIQSRDLRAAGLLKCHTCVIINGNDKTV---GFSDKSAIICATLIRSMRKLNKLKI---------------------PIMIEIRKDEI--AHHFSSIHSHNNDSKV-------------SVQHSEPFARGILFTNSTVYSCIYTVYKNPDTFSFIKTLLNGRYSDEIESMFGSGVGL-----LPQXXXXXXXXXXXXIIKLFSVIQPPLNEISRVYDGILDYACLFEWALMEKRILCLGLYRLNFGR--------NRYVFTHPEKSTEIFSTDQVYCCVSSD 3055
            +MIS  T+ GR L  V L+  L S G  V++  +  N    I  C +        ID A N+F L +F LR  AAND L FW++  ++++   +P + ++ +L     G  FLR   L +    +     ILK ++  ++  +    IS WL +AG  H+ E  G+ WE    NQQL++W C Y ++VT+STVG+G V   T  GR+ ++ +I+ G+ MF + +P +I  I N  KY   Y +    +HI+VCG     ++  FLK F  ++R      NV+IV ++    +  L    KR    +++  G++ N  DL RV I+ A   +IL+  +      +D  NIM  + +K+    +R I Q+  Y NK  L   P WN    D  +C+ ELKLG +A +CL PG++T++ NL +      + E  W+K Y  G+   +Y    S  F G+S   V  +V+    + ++AI+  ++  +  +LINP   ++KI  +  +   +A D     +  FYC  C     +   I +C  +  ++          +  N  +  S  S+ +     P +   +E+ID     +  Y   D TG F+W P  + E V L    A    LS H++VC+ G +    I L N +MPLR  N    EL+ IV +G+  Y   + W  + NFP   I+ G+P+   DLRA  +  C  CVI++ N   +      DK  I+ +  I+SM+  + + +                     P+   +R+  I    +   I    NDS V              +  ++PFA G  F  S + S +   Y N +  + I+TL+ G  + E+E++      L      PQ  ++ +R      +   ++   P  ++    DG   Y  LF  AL    +LC G+YRL             RYV T+P    E+  TD ++C +  D
Sbjct:  127 VMISAQTLTGRVL--VVLVFAL-SIGALVIYFIDSSNP---IESCQNFYKDFTLQIDMAFNVFFLLYFGLRFIAANDKLWFWLEVNSVVDFFTVPPVFVSVYLNRSWLGLRFLRALRLIQFSEILQF-LNILKTSNSIKLVNLCSIFISTWLTAAGFIHLVENSGDPWENFQNNQQLTYWECVYLLMVTMSTVGYGDVYAKTTLGRLFMVFFILGGLAMFASYVPEIIELIGNRKKYGGSYSAVSGRKHIVVCGHITLESVSNFLKDFLHKDR---DDVNVEIVFLHNISPNLELEALFKRHFTQVEFYQGSVLNPHDLARVKIESADACLILANKYCADPDAEDASNIMRVISIKNYHPKIRIITQMLQYHNKAHLLNIPSWNWKEGDDAICLAELKLGFIAQSCLAPGLSTMLANLFSMRSFIKIEEDTWQKYYLEGVANEMYTEYLSSAFVGLSFPAVCELVFAKLKLLMIAIEYKSEKRESSILINPG-NHVKIQ-EGTLGFFIASDAKEVKRAFFYCKACHDDITDPKRIKKCGCKRLEDEQPSTLSPKKKQRNGGMRNSPNSSPKLMRHDPLLIPGNEQIDNMDANVKKY---DSTGMFHWCPAKDIEKVILTRSEAAMTVLSGHVVVCIFGDVKSALIGLRNLVMPLRASNFHYHELKHIVFVGSLEYLRRE-WETLHNFPKVSILPGTPLSRADLRAVNINLCDMCVILSANQNNIDDASLQDKECILASLNIKSMQFDDSIGVLQANSQGFTPPGMDRSSPDNSPVHGLLRQPSITTGANIPIITELVNDSNVQFLDQDDDDDPDTELYLTQPFACGTAFAVSVLDSLMSATYFNDNILTLIRTLVTGGATPELEALIAEENALRGGYSTPQTLANRDRCR----VAQLALYDGPFADLG---DGGC-YGDLFCKALKTYNMLCFGIYRLRDAHLSTPSQCTKRYVITNPPYEFELVPTDLIFCLMQFD 1080

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BLAST of Calcium-activated potassium channel subunit alpha-1 vs. UniProt/SwissProt
Match: sp|O18866|KCMA1_PIG (Calcium-activated potassium channel subunit alpha-1 (Fragment) OS=Sus scrofa OX=9823 GN=KCNMA1 PE=2 SV=2)

HSP 1 Score: 349.747 bits (896), Expect = 6.362e-102
Identity = 271/975 (27.79%), Postives = 448/975 (45.95%), Query Frame = 2

Query:  323 IMISKSTIVGRFLNFVKLISQLTSWGIFVVFTFNQVNANYLIGDCFDVEGANLQWIDFALNIFCLFHFTLRAFAANDILKFWIQPTTMIEITVIPNILLTSFLPVRRQGFSFLRIYYLRELCNTIAVSFGILKVNSKFEMTKVIFYIISLWLISAGLFHMFEGIGNFWEIPLFNQQLSFWRCCYFMLVTISTVGFGSVNPLTIFGRIVVLVYIIYGITMFVTVLPNVIRTIQNLK-YKNRYISKGNERHIIVCGKFESLTIIAFLKAF-KRERFKGSVRNVKIVTMNKDLYDENLLMYMKRFSNPIKYLIGNLSNRKDLKRVNIQKAKLSVILSTPFTNKISEDDIDNIMTAMILKSQRKNMRTIVQLHLYSNKVLLKMSPMWNQNRSDIILCIDELKLGLMAYNCLTPGIATLVINLVTFTKSKSVSE-LWRKDYENGLKVLLYNVQFSDCFHGMSCLEVALIVYKLWDVCLLAIKCVNKSTDDYVLINPMIENIKIDTDSMIAIVMARDEASSNKLIFYCSKCSPQ--NQSEICQCYLEATKNSPRGHYESNLQFENQRINESFRSAYEF----PTIDSKSEEID--INSYTGLDRTGSFYWAPEPNFEDVCLDIETAESRSLSDHILVCLCG-IGHGTIDLCNFMMPLRFQNLQNSELRTIVILGNKSYFEADKWTNIKNFPMFLIIDGSPIQSRDLRAAGLLKCHTCVIINGNDKTV---GFSDKSAIICATLIRSMRKLNKLKI---------------------PIMIEIRKDEIAH--HFSSIHSHNNDSKVS-------------VQHSEPFARGILFTNSTVYSCIYTVYKNPDTFSFIKTLLNGRYSDEIESMFGSGVGL-----LPQXXXXXXXXXXXXIIKLFSVIQPPLNEISRVYDGILDYACLFEWALMEKRILCLGLYRLNFGR--------NRYVFTHPEKSTEIFSTDQVYCCVSSD 3055
            +MIS  T+ GR L  V L+  L S G  V++  +  N    I  C +        ID A N+F L +F LR  AAND L FW++  ++++   +P + ++ +L     G  FLR   L +    +     ILK ++  ++  ++   IS WL +AG  H+ E  G+ WE    NQ L++W C Y ++VT+STVG+G V   T  GR+ ++ +I+ G+ MF + +P +I  I N K Y   Y +    +HI+VCG     ++  FLK F  ++R      NV+IV ++    +  L    KR    +++  G++ N  DL RV I+ A   +IL+  +      +D  NIM  + +K+    +R I Q+  Y NK  L   P WN    D  +C+ ELKLG +A +CL  G++T++ NL +      + E  W+K Y  G+   +Y    S  F G+S   V  + +    + ++AI+  + + +  +LINP   ++KI  +  +   +A D     +  FYC  C     +   I +C  +  ++          +  N  +  S  S+ +     P +   +++ID   ++    D TG F+W      E V L    A    LS H++VC+ G +    I L N +MPLR  N    EL+ IV +G+  Y + + W  + NFP   I+ G+P+   DLRA  +  C  CVI++ N   +      DK  I+ +  I+SM+  + + +                     P+   +R+  I    +   I    ND+ V              +  ++PFA G  F  S + S +   Y N +  + I+TL+ G  + E+E++      L      PQ  ++ +R      +   +++  P  ++    DG   Y  LF  AL    +LC G+YRL             RYV T+P    E+  TD ++C +  D
Sbjct:  142 VMISAQTLTGRVL--VVLVFAL-SIGALVIYFIDSSNP---IESCQNFYKDFTLQIDMAFNVFFLLYFGLRFIAANDKLWFWLEVNSVVDFFTVPPVFVSVYLNRSWLGLRFLRALRLIQFSEILQF-LNILKTSNSIKLVNLLSIFISTWLTAAGFIHLVENSGDPWENFQNNQALTYWECVYLLMVTMSTVGYGDVYAKTTLGRLFMVFFILGGLAMFASYVPEIIELIGNRKKYGGSYSAVSGRKHIVVCGHITLESVSNFLKDFLHKDR---DDVNVEIVFLHNISPNLELEALFKRHFTQVEFYQGSVLNPHDLARVKIESADACLILANKYCADPDAEDASNIMRVISIKNYHPKIRIITQMLQYHNKAHLLNIPSWNWKEGDDAICLAELKLGFIAQSCLAQGLSTMLANLFSMRSFIKIEEDTWQKYYLEGVSNEMYTEYLSSAFVGLSFPTVCELCFVKLKLLMIAIEYKSANRESRILINPG-NHLKIQ-EGTLGFFIASDAKEVKRAFFYCKACHDDITDPKRIKKCGCKRLEDEQPSTLSPKKKQRNGGMRNSPSSSPKLMRHDPLLIPGNDQIDNMDSNVKKYDSTGMFHWCAPKEIEKVILTRSEAAMTVLSGHVVVCIFGDVSSALIGLRNLVMPLRASNFHYHELKHIVFVGSIEYLKRE-WETLHNFPKVSILPGTPLSRADLRAVNINLCDMCVILSANQNNIDDTSLQDKECILASLNIKSMQFDDSIGVLQANSQGFTPPGMDRSSPDNSPVHGMLRQPSITTGVNIPIITELVNDTNVQFLDQDDDDDPDTELYLTQPFACGTAFAVSVLDSLMSATYFNDNILTLIRTLVTGGATPELEALIAEENALRGGYSTPQTLANRDRCR----VAQLALLDGPFADLG---DGGC-YGDLFCKALKTYNMLCFGIYRLRDAHLSTPSQCTKRYVITNPPYEFELVPTDLIFCLMQFD 1095

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BLAST of Calcium-activated potassium channel subunit alpha-1 vs. UniProt/SwissProt
Match: sp|O18867|KCMA1_MACMU (Calcium-activated potassium channel subunit alpha-1 (Fragment) OS=Macaca mulatta OX=9544 GN=KCNMA1 PE=2 SV=1)

HSP 1 Score: 349.362 bits (895), Expect = 9.253e-102
Identity = 271/975 (27.79%), Postives = 448/975 (45.95%), Query Frame = 2

Query:  323 IMISKSTIVGRFLNFVKLISQLTSWGIFVVFTFNQVNANYLIGDCFDVEGANLQWIDFALNIFCLFHFTLRAFAANDILKFWIQPTTMIEITVIPNILLTSFLPVRRQGFSFLRIYYLRELCNTIAVSFGILKVNSKFEMTKVIFYIISLWLISAGLFHMFEGIGNFWEIPLFNQQLSFWRCCYFMLVTISTVGFGSVNPLTIFGRIVVLVYIIYGITMFVTVLPNVIRTIQNLK-YKNRYISKGNERHIIVCGKFESLTIIAFLKAF-KRERFKGSVRNVKIVTMNKDLYDENLLMYMKRFSNPIKYLIGNLSNRKDLKRVNIQKAKLSVILSTPFTNKISEDDIDNIMTAMILKSQRKNMRTIVQLHLYSNKVLLKMSPMWNQNRSDIILCIDELKLGLMAYNCLTPGIATLVINLVTFTKSKSVSE-LWRKDYENGLKVLLYNVQFSDCFHGMSCLEVALIVYKLWDVCLLAIKCVNKSTDDYVLINPMIENIKIDTDSMIAIVMARDEASSNKLIFYCSKCSPQ--NQSEICQCYLEATKNSPRGHYESNLQFENQRINESFRSAYEF----PTIDSKSEEID--INSYTGLDRTGSFYWAPEPNFEDVCLDIETAESRSLSDHILVCLCG-IGHGTIDLCNFMMPLRFQNLQNSELRTIVILGNKSYFEADKWTNIKNFPMFLIIDGSPIQSRDLRAAGLLKCHTCVIINGNDKTV---GFSDKSAIICATLIRSMRKLNKLKI---------------------PIMIEIRKDEIAH--HFSSIHSHNNDSKVS-------------VQHSEPFARGILFTNSTVYSCIYTVYKNPDTFSFIKTLLNGRYSDEIESMFGSGVGL-----LPQXXXXXXXXXXXXIIKLFSVIQPPLNEISRVYDGILDYACLFEWALMEKRILCLGLYRLNFGR--------NRYVFTHPEKSTEIFSTDQVYCCVSSD 3055
            +MIS  T+ GR L  V L+  L S G  V++  +  N    I  C +        ID A N+F L +F LR  AAND L FW++  ++++   +P + ++ +L     G  FLR   L +    +     ILK ++  ++  ++   IS WL +AG  H+ E  G+ WE    NQ L++W C Y ++VT+STVG+G V   T  GR+ ++ +I+ G+ MF + +P +I  I N K Y   Y +    +HI+VCG     ++  FLK F  ++R      NV+IV ++    +  L    KR    +++  G++ N  DL RV I+ A   +IL+  +      +D  NIM  + +K+    +R I Q+  Y NK  L   P WN    D  +C+ ELKLG +A +CL  G++T++ NL +      + E  W+K Y  G+   +Y    S  F G+S   V  + +    + ++AI+  + + +  +LINP   ++KI  +  +   +A D     +  FYC  C     +   I +C  +  ++          +  N  +  S  S+ +     P +   +++ID   ++    D TG F+W      E V L    A    LS H++VC+ G +    I L N +MPLR  N    EL+ IV +G+  Y + + W  + NFP   I+ G+P+   DLRA  +  C  CVI++ N   +      DK  I+ +  I+SM+  + + +                     P+   +R+  I    +   I    ND+ V              +  ++PFA G  F  S + S +   Y N +  + I+TL+ G  + E+E++      L      PQ  ++ +R      +   +++  P  ++    DG   Y  LF  AL    +LC G+YRL             RYV T+P    E+  TD ++C +  D
Sbjct:  141 VMISAQTLTGRVL--VVLVFAL-SIGALVIYFIDSSNP---IESCQNFYKDFTLQIDMAFNVFFLLYFGLRFIAANDKLWFWLEVNSVVDFFTVPPVFVSVYLNRSWLGLRFLRALRLIQFSEILQF-LNILKTSNSIKLVNLLSIFISTWLTAAGFIHLVENSGDPWENFQNNQALTYWECVYLLMVTMSTVGYGDVYAKTTLGRLFMVFFILGGLAMFASYVPEIIELIGNRKKYGGSYSAVSGRKHIVVCGHITLESVSNFLKDFLHKDR---DDVNVEIVFLHNISPNLELEALFKRHFTQVEFYQGSVLNPHDLARVKIESADACLILANKYCADPDAEDASNIMRVISIKNYHPKIRIITQMLQYHNKAHLLNIPSWNWKEGDDAICLAELKLGFIAQSCLAQGLSTMLANLFSMRSFIKIEEDTWQKYYLEGVSNEMYTEYLSSAFVGLSFPTVCELCFVKLKLLMIAIEYKSANRESRILINPG-NHLKIQ-EGTLGFFIASDAKEVKRAFFYCKACHDDITDPKRIKKCGCKRLEDEQPSTLSPKKKQRNGGMRNSPNSSPKLMRHDPLLIPGNDQIDNMDSNVKKYDSTGMFHWCAPKEIEKVILTRSEAAMTVLSGHVVVCIFGDVSSALIGLRNLVMPLRASNFHYHELKHIVFVGSIEYLKRE-WETLHNFPKVSILPGTPLSRADLRAVNINLCDMCVILSANQNNIDDTSLQDKECILASLNIKSMQFDDSIGVLQANSQGFTPPGMDRSSPDNSPVHGMLRQPSITTGVNIPIITELVNDTNVQFLDQDDDDDPDTELYLTQPFACGTAFAVSVLDSLMSATYFNDNILTLIRTLVTGGATPELEALIAEENALRGGYSTPQTLANRDRCR----VAQLALLDGPFADLG---DGGC-YGDLFCKALKTYNMLCFGIYRLRDAHLSTPSQCTKRYVITNPPYEFELVPTDLIFCLMQFD 1094

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BLAST of Calcium-activated potassium channel subunit alpha-1 vs. UniProt/SwissProt
Match: sp|Q9BG98|KCMA1_RABIT (Calcium-activated potassium channel subunit alpha-1 OS=Oryctolagus cuniculus OX=9986 GN=KCNMA1 PE=2 SV=1)

HSP 1 Score: 349.362 bits (895), Expect = 1.432e-101
Identity = 271/975 (27.79%), Postives = 448/975 (45.95%), Query Frame = 2

Query:  323 IMISKSTIVGRFLNFVKLISQLTSWGIFVVFTFNQVNANYLIGDCFDVEGANLQWIDFALNIFCLFHFTLRAFAANDILKFWIQPTTMIEITVIPNILLTSFLPVRRQGFSFLRIYYLRELCNTIAVSFGILKVNSKFEMTKVIFYIISLWLISAGLFHMFEGIGNFWEIPLFNQQLSFWRCCYFMLVTISTVGFGSVNPLTIFGRIVVLVYIIYGITMFVTVLPNVIRTIQNLK-YKNRYISKGNERHIIVCGKFESLTIIAFLKAF-KRERFKGSVRNVKIVTMNKDLYDENLLMYMKRFSNPIKYLIGNLSNRKDLKRVNIQKAKLSVILSTPFTNKISEDDIDNIMTAMILKSQRKNMRTIVQLHLYSNKVLLKMSPMWNQNRSDIILCIDELKLGLMAYNCLTPGIATLVINLVTFTKSKSVSE-LWRKDYENGLKVLLYNVQFSDCFHGMSCLEVALIVYKLWDVCLLAIKCVNKSTDDYVLINPMIENIKIDTDSMIAIVMARDEASSNKLIFYCSKCSPQ--NQSEICQCYLEATKNSPRGHYESNLQFENQRINESFRSAYEF----PTIDSKSEEID--INSYTGLDRTGSFYWAPEPNFEDVCLDIETAESRSLSDHILVCLCG-IGHGTIDLCNFMMPLRFQNLQNSELRTIVILGNKSYFEADKWTNIKNFPMFLIIDGSPIQSRDLRAAGLLKCHTCVIINGNDKTV---GFSDKSAIICATLIRSMRKLNKLKI---------------------PIMIEIRKDEIAH--HFSSIHSHNNDSKVS-------------VQHSEPFARGILFTNSTVYSCIYTVYKNPDTFSFIKTLLNGRYSDEIESMFGSGVGL-----LPQXXXXXXXXXXXXIIKLFSVIQPPLNEISRVYDGILDYACLFEWALMEKRILCLGLYRLNFGR--------NRYVFTHPEKSTEIFSTDQVYCCVSSD 3055
            +MIS  T+ GR L  V L+  L S G  V++  +  N    I  C +        ID A N+F L +F LR  AAND L FW++  ++++   +P + ++ +L     G  FLR   L +    +     ILK ++  ++  ++   IS WL +AG  H+ E  G+ WE    NQ L++W C Y ++VT+STVG+G V   T  GR+ ++ +I+ G+ MF + +P +I  I N K Y   Y +    +HI+VCG     ++  FLK F  ++R      NV+IV ++    +  L    KR    +++  G++ N  DL RV I+ A   +IL+  +      +D  NIM  + +K+    +R I Q+  Y NK  L   P WN    D  +C+ ELKLG +A +CL  G++T++ NL +      + E  W+K Y  G+   +Y    S  F G+S   V  + +    + ++AI+  + + +  +LINP   ++KI  +  +   +A D     +  FYC  C     +   I +C  +  ++          +  N  +  S  S+ +     P +   +++ID   ++    D TG F+W      E V L    A    LS H++VC+ G +    I L N +MPLR  N    EL+ IV +G+  Y + + W  + NFP   I+ G+P+   DLRA  +  C  CVI++ N   +      DK  I+ +  I+SM+  + + +                     P+   +R+  I    +   I    ND+ V              +  ++PFA G  F  S + S +   Y N +  + I+TL+ G  + E+E++      L      PQ  ++ +R      +   +++  P  ++    DG   Y  LF  AL    +LC G+YRL             RYV T+P    E+  TD ++C +  D
Sbjct:  169 VMISAQTLTGRVL--VVLVFAL-SIGALVIYFIDSSNP---IESCQNFYKDFTLQIDMAFNVFFLLYFGLRFIAANDKLWFWLEVNSVVDFFTVPPVFVSVYLNRSWLGLRFLRALRLIQFSEILQF-LNILKTSNSIKLVNLLSIFISTWLTAAGFIHLVENSGDPWENFQNNQALTYWECVYLLMVTMSTVGYGDVYAKTTLGRLFMVFFILGGLAMFASYVPEIIELIGNRKKYGGSYSAVSGRKHIVVCGHITLESVSNFLKDFLHKDR---DDVNVEIVFLHNISPNLELEALFKRHFTQVEFYQGSVLNPHDLARVKIESADACLILANKYCADPDAEDASNIMRVISIKNYHPKIRIITQMLQYHNKAHLLNIPSWNWKEGDDAICLAELKLGFIAQSCLAQGLSTMLANLFSMRSFIKIEEDTWQKYYLEGVSNEMYTEYLSSAFVGLSFPTVCELCFVKLKLLMIAIEYKSANRESRILINPG-NHLKIQ-EGTLGFFIASDAKEVKRAFFYCKACHDDITDPKRIKKCGCKRLEDEQPSTLSPKKKQRNGGMRNSPNSSPKLMRHDPLLIPGNDQIDNMDSNVKKYDSTGMFHWCAPKEIEKVILTRSEAAMTVLSGHVVVCIFGDVSSALIGLRNLVMPLRASNFHYHELKHIVFVGSIEYLKRE-WETLHNFPKVSILPGTPLSRADLRAVNINLCDMCVILSANQNNIDDTSLQDKECILASLNIKSMQFDDSIGVLQANSQGFTPPGMDRSSPDNSPVHGMLRQPSITTGVNIPIITELVNDTNVQFLDQDDDDDPDTELYLTQPFACGTAFAVSVLDSLMSATYFNDNILTLIRTLVTGGATPELEALIAEENALRGGYSTPQTLANRDRCR----VAQLALLDGPFADLG---DGGC-YGDLFCKALKTYNMLCFGIYRLRDAHLSTPSQCTKRYVITNPPYEFELVPTDLIFCLMQFD 1122

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BLAST of Calcium-activated potassium channel subunit alpha-1 vs. UniProt/SwissProt
Match: sp|Q28204|KCMA1_BOVIN (Calcium-activated potassium channel subunit alpha-1 OS=Bos taurus OX=9913 GN=KCNMA1 PE=1 SV=2)

HSP 1 Score: 348.977 bits (894), Expect = 1.436e-101
Identity = 271/975 (27.79%), Postives = 448/975 (45.95%), Query Frame = 2

Query:  323 IMISKSTIVGRFLNFVKLISQLTSWGIFVVFTFNQVNANYLIGDCFDVEGANLQWIDFALNIFCLFHFTLRAFAANDILKFWIQPTTMIEITVIPNILLTSFLPVRRQGFSFLRIYYLRELCNTIAVSFGILKVNSKFEMTKVIFYIISLWLISAGLFHMFEGIGNFWEIPLFNQQLSFWRCCYFMLVTISTVGFGSVNPLTIFGRIVVLVYIIYGITMFVTVLPNVIRTIQNLK-YKNRYISKGNERHIIVCGKFESLTIIAFLKAF-KRERFKGSVRNVKIVTMNKDLYDENLLMYMKRFSNPIKYLIGNLSNRKDLKRVNIQKAKLSVILSTPFTNKISEDDIDNIMTAMILKSQRKNMRTIVQLHLYSNKVLLKMSPMWNQNRSDIILCIDELKLGLMAYNCLTPGIATLVINLVTFTKSKSVSE-LWRKDYENGLKVLLYNVQFSDCFHGMSCLEVALIVYKLWDVCLLAIKCVNKSTDDYVLINPMIENIKIDTDSMIAIVMARDEASSNKLIFYCSKCSPQ--NQSEICQCYLEATKNSPRGHYESNLQFENQRINESFRSAYEF----PTIDSKSEEID--INSYTGLDRTGSFYWAPEPNFEDVCLDIETAESRSLSDHILVCLCG-IGHGTIDLCNFMMPLRFQNLQNSELRTIVILGNKSYFEADKWTNIKNFPMFLIIDGSPIQSRDLRAAGLLKCHTCVIINGNDKTV---GFSDKSAIICATLIRSMRKLNKLKI---------------------PIMIEIRKDEIAH--HFSSIHSHNNDSKVS-------------VQHSEPFARGILFTNSTVYSCIYTVYKNPDTFSFIKTLLNGRYSDEIESMFGSGVGL-----LPQXXXXXXXXXXXXIIKLFSVIQPPLNEISRVYDGILDYACLFEWALMEKRILCLGLYRLNFGR--------NRYVFTHPEKSTEIFSTDQVYCCVSSD 3055
            +MIS  T+ GR L  V L+  L S G  V++  +  N    I  C +        ID A N+F L +F LR  AAND L FW++  ++++   +P + ++ +L     G  FLR   L +    +     ILK ++  ++  ++   IS WL +AG  H+ E  G+ WE    NQ L++W C Y ++VT+STVG+G V   T  GR+ ++ +I+ G+ MF + +P +I  I N K Y   Y +    +HI+VCG     ++  FLK F  ++R      NV+IV ++    +  L    KR    +++  G++ N  DL RV I+ A   +IL+  +      +D  NIM  + +K+    +R I Q+  Y NK  L   P WN    D  +C+ ELKLG +A +CL  G++T++ NL +      + E  W+K Y  G+   +Y    S  F G+S   V  + +    + ++AI+  + + +  +LINP   ++KI  +  +   +A D     +  FYC  C     +   I +C  +  ++          +  N  +  S  S+ +     P +   +++ID   ++    D TG F+W      E V L    A    LS H++VC+ G +    I L N +MPLR  N    EL+ IV +G+  Y + + W  + NFP   I+ G+P+   DLRA  +  C  CVI++ N   +      DK  I+ +  I+SM+  + + +                     P+   +R+  I    +   I    ND+ V              +  ++PFA G  F  S + S +   Y N +  + I+TL+ G  + E+E++      L      PQ  ++ +R      +   +++  P  ++    DG   Y  LF  AL    +LC G+YRL             RYV T+P    E+  TD ++C +  D
Sbjct:  156 VMISAQTLTGRVL--VVLVFAL-SIGALVIYFIDSSNP---IESCQNFYKDFTLQIDMAFNVFFLLYFGLRFIAANDKLWFWLEVNSVVDFFTVPPVFVSVYLNRSWLGLRFLRALRLIQFSEILQF-LNILKTSNSIKLVNLLSIFISTWLTAAGFIHLVENSGDPWENFQNNQALTYWECVYLLMVTMSTVGYGDVYAKTTLGRLFMVFFILGGLAMFASYVPEIIELIGNRKKYGGSYSAVSGRKHIVVCGHITLESVSNFLKDFLHKDR---DDVNVEIVFLHNISPNLELEALFKRHFTQVEFYQGSVLNPHDLARVKIESADACLILANKYCADPDAEDASNIMRVISIKNYHPKIRIITQMLQYHNKAHLLNIPSWNWKEGDDAICLAELKLGFIAQSCLAQGLSTMLANLFSMRSFIKIEEDTWQKYYLEGVSNEMYTEYLSSAFVGLSFPTVCELCFVKLKLLMIAIEYKSANRESRILINPG-NHLKIQ-EGTLGFFIASDAKEVKRAFFYCKACHDDITDPKRIKKCGCKRLEDEQPSTLSPKKKQRNGGMRNSPSSSPKLMRHDPLLIPGNDQIDNMDSNVKKYDSTGMFHWCAPKEIEKVILTRSEAAMTVLSGHVVVCIFGDVSSALIGLRNLVMPLRASNFHYHELKHIVFVGSIEYLKRE-WETLHNFPKVSILPGTPLSRADLRAVNINLCDMCVILSANQNNIDDTSLQDKECILASLNIKSMQFDDSIGVLQANSQGFTPPGMDRSSPDNSPVHGMLRQPSITTGVNIPIITELVNDTNVQFLDQDDDDDPDTELYLTQPFACGTAFAVSVLDSLMSATYFNDNILTLIRTLVTGGATPELEALIAEENALRGGYSTPQTLANRDRCR----VAQLALLDGPFADLG---DGGC-YGDLFCKALKTYNMLCFGIYRLRDAHLSTPSQCTKRYVITNPPYEFELVPTDLIFCLMQFD 1109

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BLAST of Calcium-activated potassium channel subunit alpha-1 vs. TrEMBL
Match: A0A5K4EWW8 (Uncharacterized protein OS=Schistosoma mansoni OX=6183 PE=4 SV=1)

HSP 1 Score: 476.093 bits (1224), Expect = 2.010e-145
Identity = 300/998 (30.06%), Postives = 505/998 (50.60%), Query Frame = 2

Query:  296 KLNFLSFCEIMISKSTIVGRFLNFVKLISQLTSWGIFVVFTFNQVNANYLIGDCFDVEGANLQWIDFALNIFCLFHFTLRAFAANDILKFWIQPTTMIEITVIPNILLTSFLPVRRQGFSFLR----IYYLRELCNTIAVSFGILKVNSKFEMTKVIFYIISLWLISAGLFHMFEGIGNFWEIPLFNQQLSFWRCCYFMLVTISTVGFGSVNPLTIFGRIVVLVYIIYGITMFVTVLPNVIRTIQNLKYKN---RYISKGNERHIIVCGKFESLTIIAFLKAFKRE-RFKGSVRNVKIVTMNKDLYDENLLMYMKRFSNPIKYLIGNLSNRKDLKRVNIQKAKLSVILSTPFTNKISEDDIDNIMTAMILKSQRKNMRTIVQLHLYSNKVLLKMSPMWNQNRSDIILCIDELKLGLMAYNCLTPGIATLVINLVTFTKSKS---VSELWRKDYENGLKVLLYNVQFSDCFHGMSCLEVALIVYKLWDVCLLAIKCVNKSTDDYVLINPMIENIKIDTDSMIAIVMARDEASSNKLIFYCSKCSPQNQSEICQCYLEATKNSPRGHYESNLQFENQ------------------RINESFRSA----------------YEFPTIDSKSEEIDINSY------------------------TGLDRTGSFYWAPEPNFEDVCLDIETAESRSLSDHILVCLCGIG-HGTIDLCNFMMPLRFQNLQNSELRTIVILGNKSYFEADKWTNIKNFPMFLIIDGSPIQSRDLRAAGLLKCHTCVIINGNDKT-------VGFSDKSAIICATLIRSMRKLNKLKIPIMIEIRKDEIAHHFSSIHSHNNDSKVSVQHSEPFARGILFTNSTVYSCIYTVYKNPDTFSFIKTLLNGRYSDEIESMFGSGVGLLPQXXXXXXXXXXXXIIKLFSVIQPPLNEISRV-YDGILDYACLFEWALMEKRILCLGLYRLNFGRNRYVFTHPEKSTEIFSTDQVYCCVSSD 3055
            +LN   +CE   + S   G+ +  + ++    SW  +VV   N    + + G C  +    L WI+F +N+FCL ++ L+  AA D ++F +  +++I+I  IP  L + F   R    +FLR    +YY+  L        G++  N   +  +++F + ++W++ +G+ H+ E +G+FW         S++  CYF+LVT+STVG+G     +  GR+ + ++I   + +  + +P + R   N  Y N   RY     ERH+IVCG F++ +I AF+K F    + KG +R + +V +     D  L   +  +   ++Y +G  +N  DL R  +++A+ + IL+TP T    ++D  NIM A+ +K+++KN+R I+QLH + NK L+   P W    +D+++C++ELKLGLMAYNCL PG +TL++NL+    SK      E WR +YE G ++ L++V  S  F  +   ++A+ VY+ W++ LLA++ +N      +LINP+  N  ++ +SM AIV++ D +S+  L +YC  C      + C+C     +   +     +L    Q                  R    FR +                ++ P   S++ ++DINS                         + +DRTGSF+W P+       L    A S + S H LVC+ G   +G ++L NF+MPLRF       +R IVILG+       +W  +KN P   I+DG P    DL +  L +C+ CV++  + +            D+  ++CA  IRS+ +  +  + +  E+  ++ A+ FSS   H ND K+ V  SEPFARGI+F+N+ +YSC+ + + N + F F++ L++G+ +DE+E+ F  G GL  Q +    R      + L      P   ++R+     L +  ++   +   +ILCLGLYR      RYV  +P   T+I+  D  YC +  D
Sbjct:  219 QLNMKLYCERFTTVSYPAGKIMLTIYIVLSTVSWLFYVVENRNNPPVS-IRGICHTLRSKILSWINFGINLFCLGYYILKLCAATDRVRFVLSFSSLIDIISIPPALCSVFETHRHIDLNFLRSMCFLYYVDTL-----TYLGVITSNQGIQSARIVFTLFTIWMVGSGIMHVIEHLGDFWLNENHRGTWSYFESCYFLLVTLSTVGYGDYVTHSTLGRLFICIFIPVAMGVSASFVPELFRNFNN-NYTNSSDRYEPISGERHVIVCGNFDNESIRAFIKGFLYGCQAKGRMR-INMVLLRPIPLDYALKAILSPYHAWVRYFLGTPNNPHDLARTKLKEARAAFILATPNTKFRDDEDSANIMQAIAIKARKKNLRVILQLHYFRNKCLMNNFPRWTYLANDMVVCMEELKLGLMAYNCLAPGFSTLIVNLLNAHGSKPRVFEYERWRIEYEYGFRMQLHDVGISHEFSNLFIRDLAIFVYEKWNLILLAVR-INGLEKSSILINPIEVNCPVNNNSMRAIVISSDYSSALNLQYYCVTCEGHLIGQPCRCSRPVLEKRRKITIARDLALYEQIGKARENAVKAETWSYDTRSTHFFRHSFTATSPNLLHDTRNLLFDQPRGRSETRKMDINSRNLGLPNNIPVRCMNCSPIRTPSHSSQVDRTGSFHWVPDIPLTRATLSPNQAASLNFSRHFLVCVAGKSTNGPLNLENFIMPLRF---HWQRVRDIVILGDSHLIGPLEWVKLKNLPRIFIVDGDPCSFNDLHSVHLCQCNACVVLGYSAEEPHSQCVDPSLQDRVTLLCAMNIRSLLQKEQHLVHLTTELHYEKNAYLFSSGDIHENDYKLPVWFSEPFARGIIFSNTLLYSCLSSFFYNDNIFRFLRVLISGQSTDELEASFSVGAGLQQQATPQSTRMAGVK-VSLRGFRHAPFKFLTRISLRKPLTFKDVYIRCITCWQILCLGLYRWQENGFRYVIANPMPDTQIYENDMFYCFMPID 1203

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BLAST of Calcium-activated potassium channel subunit alpha-1 vs. TrEMBL
Match: A0A5K4EUY1 (Uncharacterized protein OS=Schistosoma mansoni OX=6183 PE=4 SV=1)

HSP 1 Score: 476.863 bits (1226), Expect = 2.136e-145
Identity = 300/998 (30.06%), Postives = 505/998 (50.60%), Query Frame = 2

Query:  296 KLNFLSFCEIMISKSTIVGRFLNFVKLISQLTSWGIFVVFTFNQVNANYLIGDCFDVEGANLQWIDFALNIFCLFHFTLRAFAANDILKFWIQPTTMIEITVIPNILLTSFLPVRRQGFSFLR----IYYLRELCNTIAVSFGILKVNSKFEMTKVIFYIISLWLISAGLFHMFEGIGNFWEIPLFNQQLSFWRCCYFMLVTISTVGFGSVNPLTIFGRIVVLVYIIYGITMFVTVLPNVIRTIQNLKYKN---RYISKGNERHIIVCGKFESLTIIAFLKAFKRE-RFKGSVRNVKIVTMNKDLYDENLLMYMKRFSNPIKYLIGNLSNRKDLKRVNIQKAKLSVILSTPFTNKISEDDIDNIMTAMILKSQRKNMRTIVQLHLYSNKVLLKMSPMWNQNRSDIILCIDELKLGLMAYNCLTPGIATLVINLVTFTKSKS---VSELWRKDYENGLKVLLYNVQFSDCFHGMSCLEVALIVYKLWDVCLLAIKCVNKSTDDYVLINPMIENIKIDTDSMIAIVMARDEASSNKLIFYCSKCSPQNQSEICQCYLEATKNSPRGHYESNLQFENQ------------------RINESFRSA----------------YEFPTIDSKSEEIDINSY------------------------TGLDRTGSFYWAPEPNFEDVCLDIETAESRSLSDHILVCLCGIG-HGTIDLCNFMMPLRFQNLQNSELRTIVILGNKSYFEADKWTNIKNFPMFLIIDGSPIQSRDLRAAGLLKCHTCVIINGNDKT-------VGFSDKSAIICATLIRSMRKLNKLKIPIMIEIRKDEIAHHFSSIHSHNNDSKVSVQHSEPFARGILFTNSTVYSCIYTVYKNPDTFSFIKTLLNGRYSDEIESMFGSGVGLLPQXXXXXXXXXXXXIIKLFSVIQPPLNEISRV-YDGILDYACLFEWALMEKRILCLGLYRLNFGRNRYVFTHPEKSTEIFSTDQVYCCVSSD 3055
            +LN   +CE   + S   G+ +  + ++    SW  +VV   N    + + G C  +    L WI+F +N+FCL ++ L+  AA D ++F +  +++I+I  IP  L + F   R    +FLR    +YY+  L        G++  N   +  +++F + ++W++ +G+ H+ E +G+FW         S++  CYF+LVT+STVG+G     +  GR+ + ++I   + +  + +P + R   N  Y N   RY     ERH+IVCG F++ +I AF+K F    + KG +R + +V +     D  L   +  +   ++Y +G  +N  DL R  +++A+ + IL+TP T    ++D  NIM A+ +K+++KN+R I+QLH + NK L+   P W    +D+++C++ELKLGLMAYNCL PG +TL++NL+    SK      E WR +YE G ++ L++V  S  F  +   ++A+ VY+ W++ LLA++ +N      +LINP+  N  ++ +SM AIV++ D +S+  L +YC  C      + C+C     +   +     +L    Q                  R    FR +                ++ P   S++ ++DINS                         + +DRTGSF+W P+       L    A S + S H LVC+ G   +G ++L NF+MPLRF       +R IVILG+       +W  +KN P   I+DG P    DL +  L +C+ CV++  + +            D+  ++CA  IRS+ +  +  + +  E+  ++ A+ FSS   H ND K+ V  SEPFARGI+F+N+ +YSC+ + + N + F F++ L++G+ +DE+E+ F  G GL  Q +    R      + L      P   ++R+     L +  ++   +   +ILCLGLYR      RYV  +P   T+I+  D  YC +  D
Sbjct:  254 QLNMKLYCERFTTVSYPAGKIMLTIYIVLSTVSWLFYVVENRNNPPVS-IRGICHTLRSKILSWINFGINLFCLGYYILKLCAATDRVRFVLSFSSLIDIISIPPALCSVFETHRHIDLNFLRSMCFLYYVDTL-----TYLGVITSNQGIQSARIVFTLFTIWMVGSGIMHVIEHLGDFWLNENHRGTWSYFESCYFLLVTLSTVGYGDYVTHSTLGRLFICIFIPVAMGVSASFVPELFRNFNN-NYTNSSDRYEPISGERHVIVCGNFDNESIRAFIKGFLYGCQAKGRMR-INMVLLRPIPLDYALKAILSPYHAWVRYFLGTPNNPHDLARTKLKEARAAFILATPNTKFRDDEDSANIMQAIAIKARKKNLRVILQLHYFRNKCLMNNFPRWTYLANDMVVCMEELKLGLMAYNCLAPGFSTLIVNLLNAHGSKPRVFEYERWRIEYEYGFRMQLHDVGISHEFSNLFIRDLAIFVYEKWNLILLAVR-INGLEKSSILINPIEVNCPVNNNSMRAIVISSDYSSALNLQYYCVTCEGHLIGQPCRCSRPVLEKRRKITIARDLALYEQIGKARENAVKAETWSYDTRSTHFFRHSFTATSPNLLHDTRNLLFDQPRGRSETRKMDINSRNLGLPNNIPVRCMNCSPIRTPSHSSQVDRTGSFHWVPDIPLTRATLSPNQAASLNFSRHFLVCVAGKSTNGPLNLENFIMPLRF---HWQRVRDIVILGDSHLIGPLEWVKLKNLPRIFIVDGDPCSFNDLHSVHLCQCNACVVLGYSAEEPHSQCVDPSLQDRVTLLCAMNIRSLLQKEQHLVHLTTELHYEKNAYLFSSGDIHENDYKLPVWFSEPFARGIIFSNTLLYSCLSSFFYNDNIFRFLRVLISGQSTDELEASFSVGAGLQQQATPQSTRMAGVK-VSLRGFRHAPFKFLTRISLRKPLTFKDVYIRCITCWQILCLGLYRWQENGFRYVIANPMPDTQIYENDMFYCFMPID 1238

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BLAST of Calcium-activated potassium channel subunit alpha-1 vs. TrEMBL
Match: A0A5K4EUN8 (Uncharacterized protein OS=Schistosoma mansoni OX=6183 PE=4 SV=1)

HSP 1 Score: 476.478 bits (1225), Expect = 3.506e-145
Identity = 300/998 (30.06%), Postives = 505/998 (50.60%), Query Frame = 2

Query:  296 KLNFLSFCEIMISKSTIVGRFLNFVKLISQLTSWGIFVVFTFNQVNANYLIGDCFDVEGANLQWIDFALNIFCLFHFTLRAFAANDILKFWIQPTTMIEITVIPNILLTSFLPVRRQGFSFLR----IYYLRELCNTIAVSFGILKVNSKFEMTKVIFYIISLWLISAGLFHMFEGIGNFWEIPLFNQQLSFWRCCYFMLVTISTVGFGSVNPLTIFGRIVVLVYIIYGITMFVTVLPNVIRTIQNLKYKN---RYISKGNERHIIVCGKFESLTIIAFLKAFKRE-RFKGSVRNVKIVTMNKDLYDENLLMYMKRFSNPIKYLIGNLSNRKDLKRVNIQKAKLSVILSTPFTNKISEDDIDNIMTAMILKSQRKNMRTIVQLHLYSNKVLLKMSPMWNQNRSDIILCIDELKLGLMAYNCLTPGIATLVINLVTFTKSKS---VSELWRKDYENGLKVLLYNVQFSDCFHGMSCLEVALIVYKLWDVCLLAIKCVNKSTDDYVLINPMIENIKIDTDSMIAIVMARDEASSNKLIFYCSKCSPQNQSEICQCYLEATKNSPRGHYESNLQFENQ------------------RINESFRSA----------------YEFPTIDSKSEEIDINSY------------------------TGLDRTGSFYWAPEPNFEDVCLDIETAESRSLSDHILVCLCGIG-HGTIDLCNFMMPLRFQNLQNSELRTIVILGNKSYFEADKWTNIKNFPMFLIIDGSPIQSRDLRAAGLLKCHTCVIINGNDKT-------VGFSDKSAIICATLIRSMRKLNKLKIPIMIEIRKDEIAHHFSSIHSHNNDSKVSVQHSEPFARGILFTNSTVYSCIYTVYKNPDTFSFIKTLLNGRYSDEIESMFGSGVGLLPQXXXXXXXXXXXXIIKLFSVIQPPLNEISRV-YDGILDYACLFEWALMEKRILCLGLYRLNFGRNRYVFTHPEKSTEIFSTDQVYCCVSSD 3055
            +LN   +CE   + S   G+ +  + ++    SW  +VV   N    + + G C  +    L WI+F +N+FCL ++ L+  AA D ++F +  +++I+I  IP  L + F   R    +FLR    +YY+  L        G++  N   +  +++F + ++W++ +G+ H+ E +G+FW         S++  CYF+LVT+STVG+G     +  GR+ + ++I   + +  + +P + R   N  Y N   RY     ERH+IVCG F++ +I AF+K F    + KG +R + +V +     D  L   +  +   ++Y +G  +N  DL R  +++A+ + IL+TP T    ++D  NIM A+ +K+++KN+R I+QLH + NK L+   P W    +D+++C++ELKLGLMAYNCL PG +TL++NL+    SK      E WR +YE G ++ L++V  S  F  +   ++A+ VY+ W++ LLA++ +N      +LINP+  N  ++ +SM AIV++ D +S+  L +YC  C      + C+C     +   +     +L    Q                  R    FR +                ++ P   S++ ++DINS                         + +DRTGSF+W P+       L    A S + S H LVC+ G   +G ++L NF+MPLRF       +R IVILG+       +W  +KN P   I+DG P    DL +  L +C+ CV++  + +            D+  ++CA  IRS+ +  +  + +  E+  ++ A+ FSS   H ND K+ V  SEPFARGI+F+N+ +YSC+ + + N + F F++ L++G+ +DE+E+ F  G GL  Q +    R      + L      P   ++R+     L +  ++   +   +ILCLGLYR      RYV  +P   T+I+  D  YC +  D
Sbjct:  254 QLNMKLYCERFTTVSYPAGKIMLTIYIVLSTVSWLFYVVENRNNPPVS-IRGICHTLRSKILSWINFGINLFCLGYYILKLCAATDRVRFVLSFSSLIDIISIPPALCSVFETHRHIDLNFLRSMCFLYYVDTL-----TYLGVITSNQGIQSARIVFTLFTIWMVGSGIMHVIEHLGDFWLNENHRGTWSYFESCYFLLVTLSTVGYGDYVTHSTLGRLFICIFIPVAMGVSASFVPELFRNFNN-NYTNSSDRYEPISGERHVIVCGNFDNESIRAFIKGFLYGCQAKGRMR-INMVLLRPIPLDYALKAILSPYHAWVRYFLGTPNNPHDLARTKLKEARAAFILATPNTKFRDDEDSANIMQAIAIKARKKNLRVILQLHYFRNKCLMNNFPRWTYLANDMVVCMEELKLGLMAYNCLAPGFSTLIVNLLNAHGSKPRVFEYERWRIEYEYGFRMQLHDVGISHEFSNLFIRDLAIFVYEKWNLILLAVR-INGLEKSSILINPIEVNCPVNNNSMRAIVISSDYSSALNLQYYCVTCEGHLIGQPCRCSRPVLEKRRKITIARDLALYEQIGKARENAVKAETWSYDTRSTHFFRHSFTATSPNLLHDTRNLLFDQPRGRSETRKMDINSRNLGLPNNIPVRCMNCSPIRTPSHSSQVDRTGSFHWVPDIPLTRATLSPNQAASLNFSRHFLVCVAGKSTNGPLNLENFIMPLRF---HWQRVRDIVILGDSHLIGPLEWVKLKNLPRIFIVDGDPCSFNDLHSVHLCQCNACVVLGYSAEEPHSQCVDPSLQDRVTLLCAMNIRSLLQKEQHLVHLTTELHYEKNAYLFSSGDIHENDYKLPVWFSEPFARGIIFSNTLLYSCLSSFFYNDNIFRFLRVLISGQSTDELEASFSVGAGLQQQATPQSTRMAGVK-VSLRGFRHAPFKFLTRISLRKPLTFKDVYIRCITCWQILCLGLYRWQENGFRYVIANPMPDTQIYENDMFYCFMPID 1238

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BLAST of Calcium-activated potassium channel subunit alpha-1 vs. TrEMBL
Match: A0A095ARG8 (Calcium-activated potassium channel subunit alpha-1 OS=Schistosoma haematobium OX=6185 GN=MS3_05276 PE=4 SV=1)

HSP 1 Score: 475.322 bits (1222), Expect = 4.436e-145
Identity = 301/998 (30.16%), Postives = 506/998 (50.70%), Query Frame = 2

Query:  296 KLNFLSFCEIMISKSTIVGRFLNFVKLISQLTSWGIFVVFTFNQVNANYLIGDCFDVEGANLQWIDFALNIFCLFHFTLRAFAANDILKFWIQPTTMIEITVIPNILLTSFLPVRRQGFSFLR----IYYLRELCNTIAVSFGILKVNSKFEMTKVIFYIISLWLISAGLFHMFEGIGNFWEIPLFNQQLSFWRCCYFMLVTISTVGFGSVNPLTIFGRIVVLVYIIYGITMFVTVLPNVIRTIQNLKYKN---RYISKGNERHIIVCGKFESLTIIAFLKAFKRE-RFKGSVRNVKIVTMNKDLYDENLLMYMKRFSNPIKYLIGNLSNRKDLKRVNIQKAKLSVILSTPFTNKISEDDIDNIMTAMILKSQRKNMRTIVQLHLYSNKVLLKMSPMWNQNRSDIILCIDELKLGLMAYNCLTPGIATLVINLVTFTKSKS---VSELWRKDYENGLKVLLYNVQFSDCFHGMSCLEVALIVYKLWDVCLLAIKCVNKSTDDYVLINPMIENIKIDTDSMIAIVMARDEASSNKLIFYCSKCSPQNQSEICQCYLEATKNSPRGHYESNLQFENQ------------------RINESFRSA----------------YEFPTIDSKSEEIDINSY------------------------TGLDRTGSFYWAPEPNFEDVCLDIETAESRSLSDHILVCLCGIG-HGTIDLCNFMMPLRFQNLQNSELRTIVILGNKSYFEADKWTNIKNFPMFLIIDGSPIQSRDLRAAGLLKCHTCVIINGNDKT-------VGFSDKSAIICATLIRSMRKLNKLKIPIMIEIRKDEIAHHFSSIHSHNNDSKVSVQHSEPFARGILFTNSTVYSCIYTVYKNPDTFSFIKTLLNGRYSDEIESMFGSGVGLLPQXXXXXXXXXXXXIIKLFSVIQPPLNEISRV-YDGILDYACLFEWALMEKRILCLGLYRLNFGRNRYVFTHPEKSTEIFSTDQVYCCVSSD 3055
            +LN   +CE   + S   G+ +  + ++    SW  +VV   N    + + G C  +    L WI+F +N+FCL ++ L+  AA D ++F +  +++I+I  IP  L + F   R    +FLR    +YY+  L        G++  N   +  +++F + ++W++ +G+ H+ E +G+FW         S++  CYF+LVT+STVG+G     +  GR+ + ++I   + +  + +P + R   N  Y N   RY     ERH+IVCG F++ +I AF+K F    + KG +R + +V +     D  L   +  +   ++Y +G  +N  DL R  +++A+ + IL+TP T    ++D  NIM A+ +K+++KN+R I+QLH + NK L+   P W    +D+++C++ELKLGLMAYNCL PG +TL++NL+    SK      E WR +YE G ++ L++V  S  F  +   ++A+ VY+ W++ LLAI+ +N      +LINP+  N  ++ +SM AIV++ D +S+  L +YC  C      + C+C     +   +     +L    Q                  R    FR +                ++ P   S++ ++DINS                         + +DRTGSF+W P+       L    A S + + H LVC+ G   +G ++L NF+MPLRF       +R IVILG+       +W  +KN P   I+DG P    DL +  L +C+ CV++  + +            D+  ++CA  IRS+ +  +  + +  E+  ++ A+ FSS   H ND K+ V  SEPFARGI+F+N+ +YSC+ + + N + F F++ L++G+ +DE+E+ F  G GL  Q +S   R      + L      P   ++R+     L +  ++   +   +ILCLGLYR      RYV  +P   T+I+  D  YC +  D
Sbjct:  225 QLNMKLYCERFTTVSYPAGKIMLTIYIVLSTVSWLFYVVENRNNPPVS-IRGICHTLRSKILSWINFGINLFCLGYYILKLCAATDRVRFVLSFSSLIDIISIPPALCSVFETHRHIDLNFLRSMCFLYYVDTL-----TYLGVITSNQGIQSARIVFTLFTIWMVGSGIMHVIEHLGDFWLNENHRGTWSYFESCYFLLVTLSTVGYGDYVTHSTLGRLFICIFIPVAMGVSASFVPELFRNFNN-NYTNSSDRYEPISGERHVIVCGNFDNESIRAFIKGFLYGCQAKGRMR-INMVLLRPIPLDYALKAILSPYHAWVRYFVGTPNNPHDLARTKLKEARAAFILATPNTKFRDDEDSANIMQAIAIKARKKNLRVILQLHYFRNKCLMNNFPRWTYLANDMVVCMEELKLGLMAYNCLAPGFSTLIVNLLNAHGSKPRIFEYERWRIEYEYGFRMQLHDVGISHEFSNLFIRDLAIFVYEKWNLILLAIR-INGLEKSSMLINPIDVNCPVNNNSMRAIVISSDYSSALNLQYYCITCEGHLIGQPCRCSRPVLEKRRKITIARDLALYEQIGKARENAVKAETWSYDTRSTHFFRHSFTATSPNLLHDTRNLLFDQPRGRSETRKMDINSRNLALPNNIPTRCMNYSPVRAPSHSSQVDRTGSFHWVPDIPLTRATLSPNQAASLNFNRHFLVCVAGKSTNGPLNLENFIMPLRF---HWQRVRDIVILGDSHLIGPLEWVKLKNLPRIFIVDGDPCSFNDLHSVHLCQCNACVVLGYSAEEPHSQCVDPSLQDRVTLLCAMNIRSLLQKEQHLVHLTTELHYEKNAYLFSSGDIHENDYKLPVWFSEPFARGIIFSNTLLYSCLSSFFYNDNIFRFLRVLISGQSTDELEASFSVGAGLQQQATSQSARMAGVK-VSLRGFRHAPFKFLTRISLRKPLTFKDVYIRCITCWQILCLGLYRWQENGFRYVIANPMPDTQIYENDMFYCFMPID 1209

[Close]

BLAST of Calcium-activated potassium channel subunit alpha-1 vs. TrEMBL
Match: A0A4Z2CYR9 (Calcium-activated potassium channel subunit alpha-1 OS=Schistosoma japonicum OX=6182 GN=EWB00_006294 PE=4 SV=1)

HSP 1 Score: 467.233 bits (1201), Expect = 6.864e-142
Identity = 297/998 (29.76%), Postives = 502/998 (50.30%), Query Frame = 2

Query:  296 KLNFLSFCEIMISKSTIVGRFLNFVKLISQLTSWGIFVVFTFNQVNANYLIGDCFDVEGANLQWIDFALNIFCLFHFTLRAFAANDILKFWIQPTTMIEITVIPNILLTSFLPVRRQGFSFLR----IYYLRELCNTIAVSFGILKVNSKFEMTKVIFYIISLWLISAGLFHMFEGIGNFWEIPLFNQQLSFWRCCYFMLVTISTVGFGSVNPLTIFGRIVVLVYIIYGITMFVTVLPNVIRTIQNLKYKN---RYISKGNERHIIVCGKFESLTIIAFLKAFKRE-RFKGSVRNVKIVTMNKDLYDENLLMYMKRFSNPIKYLIGNLSNRKDLKRVNIQKAKLSVILSTPFTNKISEDDIDNIMTAMILKSQRKNMRTIVQLHLYSNKVLLKMSPMWNQNRSDIILCIDELKLGLMAYNCLTPGIATLVINLVTFTKSKSV---SELWRKDYENGLKVLLYNVQFSDCFHGMSCLEVALIVYKLWDVCLLAIKCVNKSTDDYVLINPMIENIKIDTDSMIAIVMARDEASSNKLIFYCSKCSPQNQSEICQCYL----------------------EATKNSPRGHYESNLQFENQRINESFRSA------------YEFPTIDSKSEEIDINS------------------------YTGLDRTGSFYWAPEPNFEDVCLDIETAESRSLSDHILVCLCGIG-HGTIDLCNFMMPLRFQNLQNSELRTIVILGNKSYFEADKWTNIKNFPMFLIIDGSPIQSRDLRAAGLLKCHTCVIINGNDKT-------VGFSDKSAIICATLIRSMRKLNKLKIPIMIEIRKDEIAHHFSSIHSHNNDSKVSVQHSEPFARGILFTNSTVYSCIYTVYKNPDTFSFIKTLLNGRYSDEIESMFGSGVGLLPQXXXXXXXXXXXXIIKLFSVIQPPLNEISRV-YDGILDYACLFEWALMEKRILCLGLYRLNFGRNRYVFTHPEKSTEIFSTDQVYCCVSSD 3055
            +LN   +CE   + S   G+ +  V ++    SW  ++V   N    + + G C  +    L WI+F +N+FCL ++ L+  AA D ++F +  +++I+I  IP  L + F   R    +FLR    +YY+      +    G++  N   +  +++F + ++W++ +G+ H+ E +G+FW         S++  CYF+LVT+STVG+G     +  GR+ + ++I   + +  + +P + R   N  Y N   RY     ERH+IVCG F++ +I AF+K F    + KG +R + +V +     D  L   +  +   ++Y +G  +N  DL R  +++A+ + +L+TP T    ++D  NIM A+ +K+++KN+R I+QLH + NK L+   P W    +D+++C++ELKLGLMAYNCL PG +TL++NL+    SK      E WR +YE G ++ L++V  S  F  +   ++A+ VY+ W++ LLA++ VN      +LINP+  N  ++ +SM AIV++ D +S+  L +YC  C        C+C                        +A +N+ +    SN          SF +             +  P   S + +I  NS                         + +DRTGSF+W P+       L    A + +   H LVC+ G   +G ++L NF+MPLRF       +R IVILG+       +W  +KN P   I+DG P    DL +  L +C+ CV++  + +            D+  ++CA  IRS+ +  +  + +  E+  ++ A+ FSS   H ND K+ V  SEPFARGI+F+N+ +YSC+ + + N + F F++ L++G+ +DE+E+ F  G G L Q  + ++       + L      P   ++RV     L +  ++   +   +ILCLGLYR      RYV  +P   T+I+  D  YC +  D
Sbjct:  244 QLNMKLYCERFTTVSYPAGKIMLTVYILLSTLSWLFYIVENRNNPPVS-IRGICHTLRSKILSWINFCINLFCLGYYILKLCAATDRVRFVLSFSSLIDIVAIPPALCSIFETHRHIDLNFLRSICFLYYV-----DLLTYMGVIMSNQGIQSARIVFTLFTIWMVGSGIMHVIEHLGDFWLNENHRGTWSYFEACYFLLVTLSTVGYGDYVTHSTLGRLFICIFIPVSMGVSASFVPELFRNFNN-NYTNSSDRYEPISGERHVIVCGNFDNESIRAFIKGFLYGCQTKGRMR-INMVLLRPIPLDYALKAILSPYHAWVRYFVGTPNNPHDLARTKLKEARAAFVLATPNTKFRDDEDSANIMQAIAIKARKKNLRVILQLHNFRNKCLMNNFPRWTYLTNDMVVCMEELKLGLMAYNCLAPGFSTLIVNLLNAHGSKPKIFEYEQWRIEYEYGFRMQLHDVGISHEFSNLFMRDLAIFVYEKWNLILLAVR-VNGLEKSSMLINPIEVNCPVNNNSMRAIVISSDYSSALNLQYYCVTCEGHLIGRPCRCSRPVLEKRRKITIARDLALYEQIGQARENAVKAETWSNENRSTHFFRHSFTATSPDLLSDKRNLLFNQPRGRSATRKICENSINLALPDNIPSRYLNYSPTRASSHLSQVDRTGSFHWVPDIPLTRATLSPNQAATLNFRRHFLVCVAGKSTNGPLNLENFIMPLRF---HWQRVRDIVILGDSHVIGPLEWVKLKNLPRIFIVDGDPCSFNDLHSVHLCQCNACVVLGYSAEEPHSQCVDASLQDRVTLLCAMNIRSLLQKEQHLVHLTTELHYEKNAYLFSSGDIHENDYKLPVWFSEPFARGIIFSNTLLYSCLSSFFYNDNVFRFLRVLISGQSTDELEASFSVGAG-LQQGITLQSARMPGVKVSLRGFRHAPFKFLTRVPLRKPLTFKDVYIRCITCWQILCLGLYRWQENGFRYVIANPMPETQIYENDMFYCFMPID 1228

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BLAST of Calcium-activated potassium channel subunit alpha-1 vs. Ensembl Cavefish
Match: ENSAMXT00000044980.1 (pep primary_assembly:Astyanax_mexicanus-2.0:APWO02000822.1:37062:202682:-1 gene:ENSAMXG00000004398.2 transcript:ENSAMXT00000044980.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 353.984 bits (907), Expect = 3.074e-104
Identity = 285/1018 (28.00%), Postives = 461/1018 (45.28%), Query Frame = 2

Query:  323 IMISKSTIVGRFLNFVKLISQLTSWGIFVVFTFNQVNANYLIGDC--FDVEGANLQWIDFALNIFCLFHFTLRAFAANDILKFWIQPTTMIEITVIPNILLTSFLPVRRQGFSFLRIYYLRELCNTIAVSFGILKVNSKFEMTKVIFYIISLWLISAGLFHMFEGIGNFWEIPLFNQQLSFWRCCYFMLVTISTVGFGSVNPLTIFGRIVVLVYIIYGITMFVTVLPNVIRTIQNL-KYKNRYISKGNERHIIVCGKFESLTIIAFLKAF-KRERFKGSVRNVKIVTMNKDLYDENLLMYMKRFSNPIKYLIGNLSNRKDLKRVNIQKAKLSVILSTPFTNKISEDDIDNIMTAMILKSQRKNMRTIVQLHLYSNKVLLKMSPMWNQNRSDIILCIDELKLGLMAYNCLTPGIATLVINLVTFTKSKSVSE-LWRKDYENGLKVLLYNVQFSDCFHGMSCLEVALIVYKLWDVCLLAIKCVNKSTDDYVLINPMIENIKIDTDSMIAIVMARDEASSNKLIFYCSKCSPQ--NQSEICQCYLEATKNSPRGH-------YESNLQFENQRINESFRSAYE------------FPTIDSKSEEIDINSYTGLDRTGSFYWAPEPNFEDVCLDIETAESRSLSDHILVCLCG-IGHGTIDLCNFMMPLRFQNLQNSELRTIVILGNKSYFEADKWTNIKNFPMFLIIDGSPIQSRDLRAAGLLKCHTCVIINGNDKTV---GFSDKSAIICATLIRSM-----------------------------------RKLN---KLKIPIMIEIRKDE-------------IAHHFSSIHSHNNDSKV-------------SVQHSEPFARGILFTNSTVYSCIYTVYKNPDTFSFIKTLLNGRYSDEIESMFGSGVGL-----LPQXXXXXXXXXXXXIIKLFSVIQPPLNEISRVYDGILDYACLFEWALMEKRILCLGLYRLNFGR--------NRYVFTHPEKSTEIFSTDQVYCCVSSD 3055
            +MIS  T+ GR L  V L+  L+   + + F    ++++  I  C  FD E   LQ ID A NIF L +F LR  AAND L FW++  ++++   +P + ++ +L     G  FLR   L +    +     ILK ++  ++  +    IS WL +AG  H+ E  G+ WE    +Q LS+W C Y ++VT+STVG+G V   T  GR+ ++ +I+ G+ MF + +P +I  I N  KY   Y +    +HI+VCG     ++  FLK F  ++R      NV+IV ++    +  L    KR    +++  G++ N  DL RV I+ A   +IL+  +      +D  NIM  + +K+    +R I Q+  Y NK  L   P WN    D  +C+ ELKLG +A +CL  G++T++ NL +      + E  W+K Y  G+   +Y    S  F G+S   V  + Y    + L+AI+  +   +   LINP   ++K+  +  +   +A D     + ++YC  C     +   I +C  + +K++  G+       ++S L  + ++ N   R++               P+ D + E +D+N     D TG F+W P  + E V L    A    LS H++VC+ G +    + L N +MPLR  N    EL+ IV +G+  Y + + W  + NFP   I+ GSP+   DLRA  +  C  CVI++ N   +      DK  I+ +  I+SM                                   R+ +      IPI+ E+ K +             I  +   I    NDS V              +  ++PFA G  F  S + S +   Y N +  + I+TL+ G  + E+E +      L      PQ  ++ +R      +   ++   P  ++    DG   Y  LF  AL    +LC G+YRL             RYV T+P    E+  TD ++C +  D
Sbjct:  118 VMISAQTLTGRVL--VVLVFALSIGALVIYF----IDSSDPIESCQIFD-EDITLQ-IDMAFNIFFLLYFGLRFIAANDKLWFWLEVNSVVDFFTVPPVFVSVYLNRSWLGLRFLRALRLIQFSEILQF-LNILKTSNSIKLVNLCSIFISTWLTAAGFIHLVENSGDPWENFQNSQPLSYWECVYLLMVTMSTVGYGDVCAKTTLGRLFMVFFILGGLAMFASYVPEIIELIGNRKKYGGSYSAVNGRKHIVVCGHITLESVSNFLKDFLHKDR---DDVNVEIVFLHNISPNLELEALFKRHFTQVEFYQGSVLNPHDLARVKIESADACLILANKYCADPDAEDASNIMRVISIKNYHPKIRIITQMLQYHNKAHLLNIPSWNWKEGDDAICLAELKLGFIAQSCLAQGLSTMLANLFSMRSFIKIEEDTWQKYYLEGVANEMYTEYLSSAFVGLSFPAVCELCYVKLKLLLIAIEYKSDQRESSTLINPG-NHVKMQ-EGTLGFFIASDAKEVKRALYYCKACHDDITDPKRIKKCGCKRSKSNYNGYIKSIEEVHQSTLSPKKKQRNGGMRTSPNCSPKNLRHDPLLIPSHD-QMETMDVN-VKKYDSTGMFHWCPSKDIEKVILTRSEAAMTVLSGHVVVCIFGDVKSAVVGLRNLVMPLRASNFHYHELKPIVFVGSLEYLKRE-WETLHNFPKVSILPGSPLSRADLRAVNINLCDMCVILSANQNNIDDASLQDKECILASLNIKSMLFDDSIGLLQANSQGFTPPGMDRSSPENSPVHGLVRQTSVTTGANIPIITELAKSDRLLNAVCVRQDKSIGTNIPMITELVNDSNVQFLDQDDDDDPDTELYLTQPFACGTAFAVSVLDSLMSATYFNDNILTLIRTLVTGGATPELEGLLAEENALRGGYSTPQTLANRDRCR----VAQLALYDGPFADLG---DGGC-YGDLFCKALKTYNMLCFGIYRLRDAHLSAPSQCTKRYVITNPPYEFELVPTDLIFCLMQFD 1110

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BLAST of Calcium-activated potassium channel subunit alpha-1 vs. Ensembl Cavefish
Match: ENSAMXT00000050440.1 (pep primary_assembly:Astyanax_mexicanus-2.0:APWO02000822.1:48528:202682:-1 gene:ENSAMXG00000004398.2 transcript:ENSAMXT00000050440.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 350.132 bits (897), Expect = 6.546e-103
Identity = 285/1017 (28.02%), Postives = 459/1017 (45.13%), Query Frame = 2

Query:  323 IMISKSTIVGRFLNFVKLISQLTSWGIFVVFTFNQVNANYLIGDC--FDVEGANLQWIDFALNIFCLFHFTLRAFAANDILKFWIQPTTMIEITVIPNILLTSFLPVRRQGFSFLRIYYLRELCNTIAVSFGILKVNSKFEMTKVIFYIISLWLISAGLFHMFEGIGNFWEIPLFNQQLSFWRCCYFMLVTISTVGFGSVNPLTIFGRIVVLVYIIYGITMFVTVLPNVIRTIQNLK-YKNRYISKGNERHIIVCGKFESLTIIAFLKAFKRERFKGSVRNVKIVTMNKDLYDENLLMYMKRFSNPIKYLIGNLSNRKDLKRVNIQKAKLSVILSTPFTNKISEDDIDNIMTAMILKSQRKNMRTIVQLHLYSNKVLLKMSPMWNQNRSDIILCIDELKLGLMAYNCLTPGIATLVINLVTFTKSKSVSE-LWRKDYENGLKVLLYNVQFSDCFHGMSCLEVALIVYKLWDVCLLAIKCVNKSTDDYVLINPMIENIKIDTDSMIAIVMARDEASSNKLIFYCSKCSPQ--NQSEICQCYLEATKNSPRGH-------YESNLQFENQRINESFRSAYE------------FPTIDSKSEEIDINSYTGLDRTGSFYWAPEPNFEDVCLDIETAESRSLSDHILVCLCG-IGHGTIDLCNFMMPLRFQNLQNSELRTIVILGNKSYFEADKWTNIKNFPMFLIIDGSPIQSRDLRAAGLLKCHTCVIINGNDKTV---GFSDKSAIICATLIRSM-----------------------------------RKLN---KLKIPIMIEIRKDE-------------IAHHFSSIHSHNNDSKVS-------------VQHSEPFARGILFTNSTVYSCIYTVYKNPDTFSFIKTLLNGRYSDEIESMFGSGVGL-----LPQXXXXXXXXXXXXIIKLFSVIQPPLNEISRVYDGILDYACLFEWALMEKRILCLGLYRLNFGR--------NRYVFTHPEKSTEIFSTDQVYCCVSSD 3055
            +MIS  T+ GR L  V L+  L+   + + F    ++++  I  C  FD E   LQ ID A NIF L +F LR  AAND L FW++  ++++   +P + ++ +L     G  FLR   L +    +     ILK ++  ++  +    IS WL +AG  H+ E  G+ WE    +Q LS+W C Y ++VT+STVG+G V   T  GR+ ++ +I+ G+ MF   +P +   I N K Y   Y S    +HI+VCG     ++  FLK F   + +  V NV+IV ++    +  L    KR    +++  G++ N  DL RV I+ A   +IL+  +      +D  NIM  + +K+    +R I Q+  Y NK  L   P WN    D  +C+ ELKLG +A +CL  G++T++ NL +      + E  W+K Y  G+   +Y    S  F G+S   V  + Y    + L+AI+  +   +   LINP   ++K+  +  +   +A D     + ++YC  C     +   I +C  + +K++  G+       ++S L  + ++ N   R++               P+ D + E +D+N     D TG F+W P  + E V L    A    LS H++VC+ G +    + L N +MPLR  N    EL+ IV +G+  Y + + W  + NFP   I+ GSP+   DLRA  +  C  CVI++ N   +      DK  I+ +  I+SM                                   R+ +      IPI+ E+ K +             I  +   I    NDS V              +  ++PFA G  F  S + S +   Y N +  + I+TL+ G  + E+E +      L      PQ  ++ +R      +   ++   P  ++    DG   Y  LF  AL    +LC G+YRL             RYV T+P    E+  TD ++C +  D
Sbjct:  118 VMISAQTLTGRVL--VVLVFALSIGALVIYF----IDSSDPIESCQIFD-EDITLQ-IDMAFNIFFLLYFGLRFIAANDKLWFWLEVNSVVDFFTVPPVFVSVYLNRSWLGLRFLRALRLIQFSEILQF-LNILKTSNSIKLVNLCSIFISTWLTAAGFIHLVENSGDPWENFQNSQPLSYWECVYLLMVTMSTVGYGDVCAKTTLGRLFMVFFILGGLAMFARYVPEIAALILNRKKYGGTYNSTRGRKHIVVCGHITLESVSNFLKDF-LHKDRDDV-NVEIVFLHNISPNLELEALFKRHFTQVEFYQGSVLNPHDLARVKIESADACLILANKYCADPDAEDASNIMRVISIKNYHPKIRIITQMLQYHNKAHLLNIPSWNWKEGDDAICLAELKLGFIAQSCLAQGLSTMLANLFSMRSFIKIEEDTWQKYYLEGVANEMYTEYLSSAFVGLSFPAVCELCYVKLKLLLIAIEYKSDQRESSTLINPG-NHVKMQ-EGTLGFFIASDAKEVKRALYYCKACHDDITDPKRIKKCGCKRSKSNYNGYIKSIEEVHQSTLSPKKKQRNGGMRTSPNCSPKNLRHDPLLIPSHD-QMETMDVN-VKKYDSTGMFHWCPSKDIEKVILTRSEAAMTVLSGHVVVCIFGDVKSAVVGLRNLVMPLRASNFHYHELKPIVFVGSLEYLKRE-WETLHNFPKVSILPGSPLSRADLRAVNINLCDMCVILSANQNNIDDASLQDKECILASLNIKSMLFDDSIGLLQANSQGFTPPGMDRSSPENSPVHGLVRQTSVTTGANIPIITELAKSDRLLNAVCVRQDKSIGTNIPMITELVNDSNVQFLDQDDDDDPDTELYLTQPFACGTAFAVSVLDSLMSATYFNDNILTLIRTLVTGGATPELEGLLAEENALRGGYSTPQTLANRDRCR----VAQLALYDGPFADLG---DGGC-YGDLFCKALKTYNMLCFGIYRLRDAHLSAPSQCTKRYVITNPPYEFELVPTDLIFCLMQFD 1110

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BLAST of Calcium-activated potassium channel subunit alpha-1 vs. Ensembl Cavefish
Match: ENSAMXT00000050702.1 (pep primary_assembly:Astyanax_mexicanus-2.0:APWO02000822.1:37062:202682:-1 gene:ENSAMXG00000004398.2 transcript:ENSAMXT00000050702.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 349.362 bits (895), Expect = 1.245e-102
Identity = 286/1012 (28.26%), Postives = 453/1012 (44.76%), Query Frame = 2

Query:  323 IMISKSTIVGRFLNFVKLISQLTSWGIFVVFTFNQVNANYLIGDC--FDVEGANLQWIDFALNIFCLFHFTLRAFAANDILKFWIQPTTMIEITVIPNILLTSFLPVRRQGFSFLRIYYLRELCNTIAVSFGILKVNSKFEMTKVIFYIISLWLISAGLFHMFEGIGNFWEIPLFNQQLSFWRCCYFMLVTISTVGFGSVNPLTIFGRIVVLVYIIYGITMFVTVLPNVIRTIQNL-KYKNRYISKGNERHIIVCGKFESLTIIAFLKAF-KRERFKGSVRNVKIVTMNKDLYDENLLMYMKRFSNPIKYLIGNLSNRKDLKRVNIQKAKLSVILSTPFTNKISEDDIDNIMTAMILKSQRKNMRTIVQLHLYSNKVLLKMSPMWNQNRSDIILCIDELKLGLMAYNCLTPGIATLVINLVTFTKSKSVSE-LWRKDYENGLKVLLYNVQFSDCFHGMSCLEVALIVYKLWDVCLLAIKCVNKSTDDYVLINPMIENIKIDTDSMIAIVMARDEASSNKLIFYC-------------SKCSPQNQSEICQCYLEATKNSPRGHYES--NLQFENQRINESFRSAYEFPTIDSKSEEIDINSYTGLDRTGSFYWAPEPNFEDVCLDIETAESRSLSDHILVCLCG-IGHGTIDLCNFMMPLRFQNLQNSELRTIVILGNKSYFEADKWTNIKNFPMFLIIDGSPIQSRDLRAAGLLKCHTCVIINGNDKTV---GFSDKSAIICATLIRSM-----------------------------------RKLN---KLKIPIMIEIRKDE-------------IAHHFSSIHSHNNDSKV-------------SVQHSEPFARGILFTNSTVYSCIYTVYKNPDTFSFIKTLLNGRYSDEIESMFGSGVGL-----LPQXXXXXXXXXXXXIIKLFSVIQPPLNEISRVYDGILDYACLFEWALMEKRILCLGLYRLNFGR--------NRYVFTHPEKSTEIFSTDQVYCCVSSD 3055
            +MIS  T+ GR L  V L+  L+   + + F    ++++  I  C  FD E   LQ ID A NIF L +F LR  AAND L FW++  ++++   +P + ++ +L     G  FLR   L +    +     ILK ++  ++  +    IS WL +AG  H+ E  G+ WE    +Q LS+W C Y ++VT+STVG+G V   T  GR+ ++ +I+ G+ MF + +P +I  I N  KY   Y +    +HI+VCG     ++  FLK F  ++R      NV+IV ++    +  L    KR    +++  G++ N  DL RV I+ A   +IL+  +      +D  NIM  + +K+    +R I Q+  Y NK  L   P WN    D  +C+ ELKLG +A +CL  G++T++ NL +      + E  W+K Y  G+   +Y    S  F G+S   V  + Y    + L+AI+  +   +   LINP   ++K+  +  +   +A D     + ++YC              KC  +   E+ Q  L   K    G   +  N   +N R +         P+ D + E +D+N     D TG F+W P  + E V L    A    LS H++VC+ G +    + L N +MPLR  N    EL+ IV +G+  Y + + W  + NFP   I+ GSP+   DLRA  +  C  CVI++ N   +      DK  I+ +  I+SM                                   R+ +      IPI+ E+ K +             I  +   I    NDS V              +  ++PFA G  F  S + S +   Y N +  + I+TL+ G  + E+E +      L      PQ  ++ +R      +   ++   P  ++    DG   Y  LF  AL    +LC G+YRL             RYV T+P    E+  TD ++C +  D
Sbjct:  118 VMISAQTLTGRVL--VVLVFALSIGALVIYF----IDSSDPIESCQIFD-EDITLQ-IDMAFNIFFLLYFGLRFIAANDKLWFWLEVNSVVDFFTVPPVFVSVYLNRSWLGLRFLRALRLIQFSEILQF-LNILKTSNSIKLVNLCSIFISTWLTAAGFIHLVENSGDPWENFQNSQPLSYWECVYLLMVTMSTVGYGDVCAKTTLGRLFMVFFILGGLAMFASYVPEIIELIGNRKKYGGSYSAVNGRKHIVVCGHITLESVSNFLKDFLHKDR---DDVNVEIVFLHNISPNLELEALFKRHFTQVEFYQGSVLNPHDLARVKIESADACLILANKYCADPDAEDASNIMRVISIKNYHPKIRIITQMLQYHNKAHLLNIPSWNWKEGDDAICLAELKLGFIAQSCLAQGLSTMLANLFSMRSFIKIEEDTWQKYYLEGVANEMYTEYLSSAFVGLSFPAVCELCYVKLKLLLIAIEYKSDQRESSTLINPG-NHVKMQ-EGTLGFFIASDAKEVKRALYYCKACHDDITDPKRIKKCGCKRFEEVHQSTLSPKKKQRNGGMRTSPNCSPKNLRHDPLL-----IPSHD-QMETMDVN-VKKYDSTGMFHWCPSKDIEKVILTRSEAAMTVLSGHVVVCIFGDVKSAVVGLRNLVMPLRASNFHYHELKPIVFVGSLEYLKRE-WETLHNFPKVSILPGSPLSRADLRAVNINLCDMCVILSANQNNIDDASLQDKECILASLNIKSMLFDDSIGLLQANSQGFTPPGMDRSSPENSPVHGLVRQTSVTTGANIPIITELAKSDRLLNAVCVRQDKSIGTNIPMITELVNDSNVQFLDQDDDDDPDTELYLTQPFACGTAFAVSVLDSLMSATYFNDNILTLIRTLVTGGATPELEGLLAEENALRGGYSTPQTLANRDRCR----VAQLALYDGPFADLG---DGGC-YGDLFCKALKTYNMLCFGIYRLRDAHLSAPSQCTKRYVITNPPYEFELVPTDLIFCLMQFD 1099

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BLAST of Calcium-activated potassium channel subunit alpha-1 vs. Ensembl Cavefish
Match: ENSAMXT00000051878.1 (pep primary_assembly:Astyanax_mexicanus-2.0:APWO02000822.1:37062:202682:-1 gene:ENSAMXG00000004398.2 transcript:ENSAMXT00000051878.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 336.265 bits (861), Expect = 8.795e-98
Identity = 284/1044 (27.20%), Postives = 460/1044 (44.06%), Query Frame = 2

Query:  323 IMISKSTIVGRFLNFVKLISQLTSWGIFVVFTFNQVNANYLIGDC--FDVEGANLQWIDFALNIFCLFHFTLRAFAANDILKFWIQPTTMIEITVIPNILLTSFLPVRRQGFSFLRIYYLRELCNTIAVSFGILKVNSKFEMTKVIFYIISLWLISAGLFHMFEGIGNFWEIPLFNQQLSFWRCCYFMLVTISTVGFGSVNPLTIFGRIVVLVYIIYGITMFVTVLPNVIRTIQNLK-YKNRYISKGNERHIIVCGKFESLTIIAFLKAFKRERFKGSVRNVKIVTMNKDLYDENLLMYMKRFSNPIKYLIGNLSNRKDLKRVNIQKAKLSVILSTPFTNKISEDDIDNIMTAMILKSQRKNMRTIVQLHLYSNKVLLKMSPMWNQNRSDIILCIDELKLGLMAYNCLTPGIATLVINLVTFTKSKSVSE-LWRKDYENGLKVLLYNVQFSDCFHGMSCLEVALIVYKLWDVCLLAIKCVNKSTDDYVLINPMIENIKIDTDSMIAIVMARDEASSNKLIFYCS-------------KCSPQNQSEICQ------CYLE----------------------------------ATKNSPRGHY-----------ESNLQFENQRINESFRSAYE------------FPTIDSKSEEIDINSYTGLDRTGSFYWAPEPNFEDVCLDIETAESRSLSDHILVCLCG-IGHGTIDLCNFMMPLRFQNLQNSELRTIVILGNKSYFEADKWTNIKNFPMFLIIDGSPIQSRDLRAAGLLKCHTCVIINGNDKTV---GFSDKSAIICATLIRSMRKLNKLKI---------------------PIMIEIRKDEI--AHHFSSIHSHNNDSKV-------------SVQHSEPFARGILFTNSTVYSCIYTVYKNPDTFSFIKTLLNGRYSDEIESMFGSGVGL-----LPQXXXXXXXXXXXXIIKLFSVIQPPLNEISRVYDGILDYACLFEWALMEKRILCLGLYRLNFGR--------NRYVFTHPEKSTEIFSTDQVYCCVSSD 3055
            +MIS  T+ GR L  V L+  L+   + + F    ++++  I  C  FD E   LQ ID A NIF L +F LR  AAND L FW++  ++++   +P + ++ +L     G  FLR   L +    +     ILK ++  ++  +    IS WL +AG  H+ E  G+ WE    +Q LS+W C Y ++VT+STVG+G V   T  GR+ ++ +I+ G+ MF + +P +I  I N K Y   Y +    +HI+VCG     ++  FLK F   + +  V NV+IV ++    +  L    KR    +++  G++ N  DL RV I+ A   +IL+  +      +D  NIM  + +K+    +R I Q+  Y NK  L   P WN    D  +C+ ELKLG +A +CL  G++T++ NL +      + E  W+K Y  G+   +Y    S  F G+S   V  + Y    + L+AI+  +   +   LINP   ++K+  +  +   +A D     + ++YC              KC  +   + C+      C L+                                  AT  S + +Y           +S L  + ++ N   R++               P+ D + E +D+N     D TG F+W P  + E V L    A    LS H++VC+ G +    + L N +MPLR  N    EL+ IV +G+  Y + + W  + NFP   I+ GSP+   DLRA  +  C  CVI++ N   +      DK  I+ +  I+SM   + + +                     P+   +R+  +    +   I    NDS V              +  ++PFA G  F  S + S +   Y N +  + I+TL+ G  + E+E +      L      PQ  ++ +R      +   ++   P  ++    DG   Y  LF  AL    +LC G+YRL             RYV T+P    E+  TD ++C +  D
Sbjct:  118 VMISAQTLTGRVL--VVLVFALSIGALVIYF----IDSSDPIESCQIFD-EDITLQ-IDMAFNIFFLLYFGLRFIAANDKLWFWLEVNSVVDFFTVPPVFVSVYLNRSWLGLRFLRALRLIQFSEILQF-LNILKTSNSIKLVNLCSIFISTWLTAAGFIHLVENSGDPWENFQNSQPLSYWECVYLLMVTMSTVGYGDVCAKTTLGRLFMVFFILGGLAMFASYVPEIIELIGNRKKYGGSYSAVNGRKHIVVCGHITLESVSNFLKDF-LHKDRDDV-NVEIVFLHNISPNLELEALFKRHFTQVEFYQGSVLNPHDLARVKIESADACLILANKYCADPDAEDASNIMRVISIKNYHPKIRIITQMLQYHNKAHLLNIPSWNWKEGDDAICLAELKLGFIAQSCLAQGLSTMLANLFSMRSFIKIEEDTWQKYYLEGVANEMYTEYLSSAFVGLSFPAVCELCYVKLKLLLIAIEYKSDQRESSTLINPG-NHVKMQ-EGTLGFFIASDAKEVKRALYYCKACHDDITDPKRIKKCGCKRSKKACRRGTRLACCLDCGEADYGCLCMSRSVRSNAETAFPLSPTCLSDNSATLRSSKSNYNGYIKSIEEVHQSTLSPKKKQRNGGMRTSPNCSPKNLRHDPLLIPSHD-QMETMDVN-VKKYDSTGMFHWCPSKDIEKVILTRSEAAMTVLSGHVVVCIFGDVKSAVVGLRNLVMPLRASNFHYHELKPIVFVGSLEYLKRE-WETLHNFPKVSILPGSPLSRADLRAVNINLCDMCVILSANQNNIDDASLQDKECILASLNIKSMLFDDSIGLLQANSQGFTPPGMDRSSPENSPVHGLVRQTSVTTGANIPIITELVNDSNVQFLDQDDDDDPDTELYLTQPFACGTAFAVSVLDSLMSATYFNDNILTLIRTLVTGGATPELEGLLAEENALRGGYSTPQTLANRDRCR----VAQLALYDGPFADLG---DGGC-YGDLFCKALKTYNMLCFGIYRLRDAHLSAPSQCTKRYVITNPPYEFELVPTDLIFCLMQFD 1137

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BLAST of Calcium-activated potassium channel subunit alpha-1 vs. Ensembl Cavefish
Match: ENSAMXT00000004500.2 (pep primary_assembly:Astyanax_mexicanus-2.0:APWO02000822.1:37062:202682:-1 gene:ENSAMXG00000004398.2 transcript:ENSAMXT00000004500.2 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 333.183 bits (853), Expect = 1.845e-96
Identity = 289/1072 (26.96%), Postives = 463/1072 (43.19%), Query Frame = 2

Query:  323 IMISKSTIVGRFLNFVKLISQLTSWGIFVVFTFNQVNANYLIGDC--FDVEGANLQWIDFALNIFCLFHFTLRAFAANDILKFWIQPTTMIEITVIPNILLTSFLPVRRQGFSFLRIYYLRELCNTIAVSFGILKVNSKFEMTKVIFYIISLWLISAGLFHMFEGIGNFWEIPLFNQQLSFWRCCYFMLVTISTVGFGSVNPLTIFGRIVVLVYIIYGITMFVTVLPNVIRTIQNLK-YKNRYISKGNERHIIVCGKFESLTIIAFLKAFKRERFKGSVRNVKIVTMNKDLYDENLLMYMKRFSNPIKYLIGNLSNRKDLKRVNIQKAKLSVILSTPFTNKISEDDIDNIMTAMILKSQRKNMRTIVQLHLYSNKVLLKMSPMWNQNRSDIILCIDELKLGLMAYNCLTPGIATLVINLVTFTKSKSVSE-LWRKDYENGLKVLLYNVQFSDCFHGMSCLEVALIVYKLWDVCLLAIKCVNKSTDDYVLINPMIENIKIDTDSMIAIVMARDEASSNKLIFYCS-------------KCSPQNQSEICQ------CYLE----------------------------------ATKNSPRGHY-----------ESNLQFENQRINESFRSAYE------------FPTIDSKSEEIDINSYTGLDRTGSFYWAPEPNFEDVCLDIETAESRSLSDHILVCLCG-IGHGTIDLCNFMMPLRFQNLQNSELRTIVILGNKSYFEADKWTNIKNFPMFLIIDGSPIQSRDLRAAGLLKCHTCVIINGNDKTV---GFSDKSAIICATLIRSM-----------------------------------RKLN---KLKIPIMIEIRKDE-------------IAHHFSSIHSHNNDSKV-------------SVQHSEPFARGILFTNSTVYSCIYTVYKNPDTFSFIKTLLNGRYSDEIESMFGSGVGL-----LPQXXXXXXXXXXXXIIKLFSVIQPPLNEISRVYDGILDYACLFEWALMEKRILCLGLYRLNFGR--------NRYVFTHPEKSTEIFSTDQVYCCVSSD 3055
            +MIS  T+ GR L  V L+  L+   + + F    ++++  I  C  FD E   LQ ID A NIF L +F LR  AAND L FW++  ++++   +P + ++ +L     G  FLR   L +    +     ILK ++  ++  +    IS WL +AG  H+ E  G+ WE    +Q LS+W C Y ++VT+STVG+G V   T  GR+ ++ +I+ G+ MF + +P +I  I N K Y   Y +    +HI+VCG     ++  FLK F   + +  V NV+IV ++    +  L    KR    +++  G++ N  DL RV I+ A   +IL+  +      +D  NIM  + +K+    +R I Q+  Y NK  L   P WN    D  +C+ ELKLG +A +CL  G++T++ NL +      + E  W+K Y  G+   +Y    S  F G+S   V  + Y    + L+AI+  +   +   LINP   ++K+  +  +   +A D     + ++YC              KC  +   + C+      C L+                                  AT  S + +Y           +S L  + ++ N   R++               P+ D + E +D+N     D TG F+W P  + E V L    A    LS H++VC+ G +    + L N +MPLR  N    EL+ IV +G+  Y + + W  + NFP   I+ GSP+   DLRA  +  C  CVI++ N   +      DK  I+ +  I+SM                                   R+ +      IPI+ E+ K +             I  +   I    NDS V              +  ++PFA G  F  S + S +   Y N +  + I+TL+ G  + E+E +      L      PQ  ++ +R      +   ++   P  ++    DG   Y  LF  AL    +LC G+YRL             RYV T+P    E+  TD ++C +  D
Sbjct:  118 VMISAQTLTGRVL--VVLVFALSIGALVIYF----IDSSDPIESCQIFD-EDITLQ-IDMAFNIFFLLYFGLRFIAANDKLWFWLEVNSVVDFFTVPPVFVSVYLNRSWLGLRFLRALRLIQFSEILQF-LNILKTSNSIKLVNLCSIFISTWLTAAGFIHLVENSGDPWENFQNSQPLSYWECVYLLMVTMSTVGYGDVCAKTTLGRLFMVFFILGGLAMFASYVPEIIELIGNRKKYGGSYSAVNGRKHIVVCGHITLESVSNFLKDF-LHKDRDDV-NVEIVFLHNISPNLELEALFKRHFTQVEFYQGSVLNPHDLARVKIESADACLILANKYCADPDAEDASNIMRVISIKNYHPKIRIITQMLQYHNKAHLLNIPSWNWKEGDDAICLAELKLGFIAQSCLAQGLSTMLANLFSMRSFIKIEEDTWQKYYLEGVANEMYTEYLSSAFVGLSFPAVCELCYVKLKLLLIAIEYKSDQRESSTLINPG-NHVKMQ-EGTLGFFIASDAKEVKRALYYCKACHDDITDPKRIKKCGCKRSKKACRRGTRLACCLDCGEADYGCLCMSRSVRSNAETAFPLSPTCLSDNSATLRSSKSNYNGYIKSIEEVHQSTLSPKKKQRNGGMRTSPNCSPKNLRHDPLLIPSHD-QMETMDVN-VKKYDSTGMFHWCPSKDIEKVILTRSEAAMTVLSGHVVVCIFGDVKSAVVGLRNLVMPLRASNFHYHELKPIVFVGSLEYLKRE-WETLHNFPKVSILPGSPLSRADLRAVNINLCDMCVILSANQNNIDDASLQDKECILASLNIKSMLFDDSIGLLQANSQGFTPPGMDRSSPENSPVHGLVRQTSVTTGANIPIITELAKSDRLLNAVCVRQDKSIGTNIPMITELVNDSNVQFLDQDDDDDPDTELYLTQPFACGTAFAVSVLDSLMSATYFNDNILTLIRTLVTGGATPELEGLLAEENALRGGYSTPQTLANRDRCR----VAQLALYDGPFADLG---DGGC-YGDLFCKALKTYNMLCFGIYRLRDAHLSAPSQCTKRYVITNPPYEFELVPTDLIFCLMQFD 1165

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BLAST of Calcium-activated potassium channel subunit alpha-1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000006399.1 (pep scaffold:Pmarinus_7.0:GL477091:41003:110164:-1 gene:ENSPMAG00000005728.1 transcript:ENSPMAT00000006399.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 171.785 bits (434), Expect = 7.534e-47
Identity = 107/365 (29.32%), Postives = 185/365 (50.68%), Query Frame = 2

Query:  806 EGIGNFWEIPLFNQQLSFWRCCYFMLVTISTVGFGSVNPLTIFGRIVVLVYIIYGITMFVTVLPNVIRTIQNL-KYKNRYISKGNERHIIVCGKFESLTIIAFLKAF-KRERFKGSVRNVKIVTMNKDLYDENLLMYMKRFSNPIKYLIGNLSNRKDLKRVNIQKAKLSVILSTPFTNKISEDDIDNIMTAMILKSQRKNMRTIVQLHLYSNKVLLKMSPMWNQNRSDIILCIDELKLGLMAYNCLTPGIATLVINLVTFTKSKSVSE-LWRKDYENGLKVLLYNVQFSDCFHGMSCLEVALIVYKLWDVCLLAIKCVNK-STDDYVLINPMIENIKIDTDSMIAIVMARDEASSNKLIFYCSKC 1888
            E  G+ W      Q L++W C Y ++VT+STVG+G V   T  GR+ ++ +I+ G+ MF   +P +   I N  KY   Y+     +H++VCG     ++  FLK F  ++R   +V  + + +++ +L  E L    +R    +++  G++ N  DL RV I+ A   +I++  +      +D  NIM  + +K+    +R I Q+  Y NK  L   P W+    D  +C+ ELKLG +A +CL  GI+T++ NL +      + E  W+K Y  G+   +Y    S  F G+S   V+ + +    + L+AI+  ++ S    +L+NP   +++I  D  +A  +A D     +  +YC  C
Sbjct:    1 ENSGDPWRDFQNQQNLTYWECVYLLMVTMSTVGYGDVYAKTTLGRLFMVFFILGGLAMFARYVPEIAALILNRRKYGGEYLPTRGRKHVVVCGHITLESVSNFLKDFLHKDRDDVNVEILFLHSISPNLELEALF---RRHFTQVEFYQGSVLNPLDLARVKIEAADACMIIANKYCPDPDAEDASNIMRVISIKNYHPRIRVITQMLQYHNKAHLLNIPSWSWREGDAAICLSELKLGFIAQSCLAQGISTMLANLFSMRSYIKIEEDTWQKFYLEGVSNEMYTEYLSSAFVGLSFPAVSELCFVKLRLLLIAIEYRSEHSYGSSILLNPG-SHVRIQ-DGTLAFFIANDSKEVKRAFYYCKAC 360

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BLAST of Calcium-activated potassium channel subunit alpha-1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000006404.1 (pep scaffold:Pmarinus_7.0:GL477091:42221:110230:-1 gene:ENSPMAG00000005728.1 transcript:ENSPMAT00000006404.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 171.785 bits (434), Expect = 9.581e-47
Identity = 107/365 (29.32%), Postives = 185/365 (50.68%), Query Frame = 2

Query:  806 EGIGNFWEIPLFNQQLSFWRCCYFMLVTISTVGFGSVNPLTIFGRIVVLVYIIYGITMFVTVLPNVIRTIQNL-KYKNRYISKGNERHIIVCGKFESLTIIAFLKAF-KRERFKGSVRNVKIVTMNKDLYDENLLMYMKRFSNPIKYLIGNLSNRKDLKRVNIQKAKLSVILSTPFTNKISEDDIDNIMTAMILKSQRKNMRTIVQLHLYSNKVLLKMSPMWNQNRSDIILCIDELKLGLMAYNCLTPGIATLVINLVTFTKSKSVSE-LWRKDYENGLKVLLYNVQFSDCFHGMSCLEVALIVYKLWDVCLLAIKCVNK-STDDYVLINPMIENIKIDTDSMIAIVMARDEASSNKLIFYCSKC 1888
            E  G+ W      Q L++W C Y ++VT+STVG+G V   T  GR+ ++ +I+ G+ MF   +P +   I N  KY   Y+     +H++VCG     ++  FLK F  ++R   +V  + + +++ +L  E L    +R    +++  G++ N  DL RV I+ A   +I++  +      +D  NIM  + +K+    +R I Q+  Y NK  L   P W+    D  +C+ ELKLG +A +CL  GI+T++ NL +      + E  W+K Y  G+   +Y    S  F G+S   V+ + +    + L+AI+  ++ S    +L+NP   +++I  D  +A  +A D     +  +YC  C
Sbjct:   23 ENSGDPWRDFQNQQNLTYWECVYLLMVTMSTVGYGDVYAKTTLGRLFMVFFILGGLAMFARYVPEIAALILNRRKYGGEYLPTRGRKHVVVCGHITLESVSNFLKDFLHKDRDDVNVEILFLHSISPNLELEALF---RRHFTQVEFYQGSVLNPLDLARVKIEAADACMIIANKYCPDPDAEDASNIMRVISIKNYHPRIRVITQMLQYHNKAHLLNIPSWSWREGDAAICLSELKLGFIAQSCLAQGISTMLANLFSMRSYIKIEEDTWQKFYLEGVSNEMYTEYLSSAFVGLSFPAVSELCFVKLRLLLIAIEYRSEHSYGSSILLNPG-SHVRIQ-DGTLAFFIANDSKEVKRAFYYCKAC 382

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BLAST of Calcium-activated potassium channel subunit alpha-1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000007042.1 (pep scaffold:Pmarinus_7.0:GL486096:7796:16492:-1 gene:ENSPMAG00000006371.1 transcript:ENSPMAT00000007042.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 108.227 bits (269), Expect = 8.740e-27
Identity = 67/216 (31.02%), Postives = 107/216 (49.54%), Query Frame = 2

Query: 1061 RHIIVCGKFESLTIIAFLKAFKRERFKGSVRNVKIVTMNKDLYDENLLMYMKRFSNPIKYLIGNLSNRKDLKRVNIQKAKLSVILSTPFTNKISEDDIDNIMTAMILKSQRKNMRTIVQLHLYSNKVLLKMSPMWNQNRSDIILCIDELKLGLMAYNCLTPGIATLVINLVTFTK--------SKSVSELWRKDYENGLKVLLYNVQFSDCFHGMS 1684
            RHI+VCG     ++  FLK F   + +  V NV+IV ++    +  L    KR    +++  G++ N  DL RV I+ A   +IL+  +      +D  NIM  + +K+    +R I Q+  Y NK  L   P WN    D  +C+ ELKLG +A +CL PG++T++ NL +            +   + W+K Y  G+   +Y    S+ F G+S
Sbjct:    1 RHIVVCGHITLESVSNFLKDF-LHKDRDDV-NVEIVFLHNISPNLELEALFKRHFTQVEFYQGSVLNPHDLARVKIEAADACLILANKYCGDPDAEDASNIMRVISIKNYHPRIRVITQMQQYHNKAHLLNIPSWNWKEGDDAICLAELKLGFIAQSCLAPGLSTMLANLFSMRSYIKRVPLPHQIEEDTWQKYYLEGVSNEMYTEYLSNAFTGLS 214

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BLAST of Calcium-activated potassium channel subunit alpha-1 vs. Ensembl Sea Lamprey
Match: KCNT1 (potassium sodium-activated channel subfamily T member 1 [Source:HGNC Symbol;Acc:HGNC:18865])

HSP 1 Score: 54.6842 bits (130), Expect = 6.646e-8
Identity = 59/228 (25.88%), Postives = 97/228 (42.54%), Query Frame = 2

Query:  800 MFEGIGNFWEIPLFNQQLSFWRCCYFMLVTISTVGFGSVNPLTIFGRIVVLVYIIYGITMFVTVLPNVIRTIQNLKYKNRYISKGN--------ERHIIVCGKFESLTIIA-FLKAFKRERFKGSVRNVKIVTMNKDLYDENLLMYMKRFSNPIKYLIGNLSNRKDLKRVNIQKAKLSVILSTPFTNKISEDDIDNIMTAMILKSQRKNMRTIVQLHLYSNKVLLKMS 1456
            MF  I  F  +    + +S +R  YF +VT STVGFG V P     +++V++ I   +     VLP     +  L Y  R  S GN        E+H+++C     L ++  FL  F           V +   + D     +L ++  ++  + YL G+    +DL RV I  A+   IL++      +  D   I+ A  +K    +    VQ+    NK  +K +
Sbjct:  205 MFTFICGFQHLERAAENISLFRSLYFCIVTFSTVGFGDVLPKIWPSQLLVVIMICVAL----MVLPVQFEELVYL-YMERQKSGGNYSRYRAQTEKHVVLCVSSLKLDLLMDFLNEFYAHPRLQDFYTVILCPTDMDSQVRRML-HVPLWAQRVIYLQGSALKDQDLVRVKIDDAEACFILTSRNEVDRTAADHQTILRAWAVKDFAPSCPLYVQILKPENKFHVKFA 426

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BLAST of Calcium-activated potassium channel subunit alpha-1 vs. Ensembl Nematostella
Match: EDO32743 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SU69])

HSP 1 Score: 74.7146 bits (182), Expect = 1.633e-13
Identity = 133/611 (21.77%), Postives = 242/611 (39.61%), Query Frame = 2

Query:  848 QLSFWRCCYFMLVTISTVGFGSVNPLTIFGRIVVLVYIIYGITMFVTVLPNVIRTIQNLKYKNR-------YISKGNERHIIVCGK-FESLTIIAFLKAFKRERFKGSVRNVKIVTMNKDLYDENL--LMYMKRFSNPIKYLIGNLSNRKDLKRVNIQKAKLSVILSTPFTNKISEDDIDNIMTAMILKSQRKNMRTIVQLHLYSNKVLLKMSPMWNQNRSDIILCIDELKLGLMAYNCLTPGIATLVINLVTFTKSKSV--SELWRKDYENGLKVLLYNVQFSDC-----FHGMSCLEVALIVYKLWDVCLLAIKCVNKSTDDYVLINPMIENIKIDTDSMIAIVMARDEASSNKLIFYCSKCSPQNQSEICQCYL-----------------------EATKNSPRGHYESNLQ---------FENQRINESFRSAY--EFPTIDSKSEEIDINSYTG---------------LDRTG---SFYWAPEPNFEDVCLDI-ETAESRSLSDHILVCLCGIGHGTI---------DLCNFMMPLRFQNLQNSELRTIVIL----GNKSYFEADKWTNIKNFPMFLIIDGSPIQSRDLRAAGLLKCHTCVIIN 2431
            Q S  +  +F++VT STVG+G   P     +  V++ I  GI +   +LP  +  +  L +  +       ++  G +RH+++C     + T+I FL  F  +     + +V +V +     D  L  L+ +  ++  + YL G+    +DL R   + A    IL+  +       D   I+    ++         VQ+        LK    ++ + ++ ++C DE+K  L+A NC+ PGI+TLV  L+     + V  SE W + Y       +Y+++  D      +   S    A   +K + V L+ +K   K     +++NP   +     D    I ++ +E ++ K         P+    +   +                        + ++NSP    E  L          FE      S  SA+  +   +DS++ E++I +                  + RT      Y  P+P     CL + E  E R +SD +   +    HG I          L NF++PLR  +     L+ I++L     N+ + EA     + +FPM   + G+     +L  AG L   + V++ 
Sbjct:  249 QWSMMKTLWFVIVTFSTVGYGDTVPTHWTTQTFVMIMI--GIAL--VLLPIELERLAFLLFSRQKEGGAYNHLLAGTDRHVVLCATTLRTGTLIDFLNEFYAD---SRLHDVHVVLLCPSDLDSTLRILLQVPVWAQRVTYLKGSALIDEDLVRAR-RNAAGCFILADRYAADREAADQHTILRTWAIQDFAPATPLFVQI--------LKPENKFHVSFAEHVVCEDEIKHALLAVNCVCPGISTLVTLLLHTLHEQYVRGSEKWHEIYGKCAGNEIYDIRLGDSMIFRPYAYKSFTHAAFHAHKKYGVTLIGVKRHGKGGR--LMLNPGPSHNMAYDDRCFYIAISSEEDTAFK-----KYEEPKKTKRLSSNHFKKNSFVTASSVALELRGDGSLAGDQSENSPPRPTEGGLDGTARLKEVTFEVGDSRRSSASAFVPDESDMDSETGEMEIENLPSRIPNYIVGVLPVSPYIGRTPMRCHLYQTPKPF---CCLRLNEDCEHREMSDSVR--MHRQQHGGIIVSSPVAEAGLYNFILPLRAYHRPKITLKPIILLLGEEPNEDFLEA-----VCHFPMLYYMVGTINSLDNLLEAGCLYADSIVVVG 826

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BLAST of Calcium-activated potassium channel subunit alpha-1 vs. Ensembl Nematostella
Match: EDO28098 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T7F3])

HSP 1 Score: 55.4546 bits (132), Expect = 1.019e-8
Identity = 34/85 (40.00%), Postives = 45/85 (52.94%), Query Frame = 2

Query: 2141 ETAESRSLSDHILVCLCGIGHGT-IDLCNFMMPLRFQNLQNSELRTIVILGNKSYFEADKWTNIKNFPMFLIIDGSPIQSRDLRA 2392
            E A +   + HILVC+        + L   +MPLR  NL  S+L+ IV LG+K Y + + W  I NF    I+ GSP    DLRA
Sbjct:   62 EMASNVIFTHHILVCVFNKKEDPLVGLRKMVMPLRASNLHRSDLKKIVFLGDKDYMKLE-WEEICNFHEVYILPGSPFCRADLRA 145

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BLAST of Calcium-activated potassium channel subunit alpha-1 vs. Ensembl Medaka
Match: ENSORLT00000011055.2 (potassium calcium-activated channel subfamily M alpha 1 [Source:NCBI gene;Acc:101155390])

HSP 1 Score: 350.132 bits (897), Expect = 3.496e-103
Identity = 276/977 (28.25%), Postives = 449/977 (45.96%), Query Frame = 2

Query:  323 IMISKSTIVGRFLNFVKLISQLTSWGIFVVFTFNQVNANYLIGDCFDVEGANLQWIDFALNIFCLFHFTLRAFAANDILKFWIQPTTMIEITVIPNILLTSFLPVRRQGFSFLRIYYLRELCNTIAVSFGILKVNSKFEMTKVIFYIISLWLISAGLFHMFEGIGNFWEIPLFNQQLSFWRCCYFMLVTISTVGFGSVNPLTIFGRIVVLVYIIYGITMFVTVLPNVIRTIQNL-KYKNRYISKGNERHIIVCGKFESLTIIAFLKAF-KRERFKGSVRNVKIVTMNKDLYDENLLMYMKRFSNPIKYLIGNLSNRKDLKRVNIQKAKLSVILSTPFTNKISEDDIDNIMTAMILKSQRKNMRTIVQLHLYSNKVLLKMSPMWNQNRSDIILCIDELKLGLMAYNCLTPGIATLVINLVTFTKSKSVSE-LWRKDYENGLKVLLYNVQFSDCFHGMSCLEVALIVYKLWDVCLLAIKCVNKSTDDYVLINPMIENIKIDTDSMIAIVMARDEASSNKLIFYCSKC----SPQNQSEICQC-YLEATKN---SPRGHYESNLQFENQRINESFRSAYEFPTIDSKSEEIDI--NSYTGLDRTGSFYWAPEPNFEDVCLDIETAESRSLSDHILVCLCG-IGHGTIDLCNFMMPLRFQNLQNSELRTIVILGNKSYFEADKWTNIKNFPMFLIIDGSPIQSRDLRAAGLLKCHTCVIINGNDKTV---GFSDKSAIICATLIRSMRKLNKLKI---------------------PIMIEIRKDEI--AHHFSSIHSHNNDSKV-------------SVQHSEPFARGILFTNSTVYSCIYTVYKNPDTFSFIKTLLNGRYSDEIESMFGSGVGL-----LPQXXXXXXXXXXXXIIKLFSVIQPPLNEISRVYDGILDYACLFEWALMEKRILCLGLYRLNFGR--------NRYVFTHPEKSTEIFSTDQVYCCVSSD 3055
            +MIS  T+ GR L  V L+  L+   + + F    ++++  I  C          ID A NIF L +F LR  AAND L FW++  ++++   +P + ++ +L     G  FLR   L +    +     ILK ++  ++  +    IS WL +AG  H+ E  G+ WE    +Q LS+W C Y ++VT+STVG+G V   T  GR+ ++ +I+ G+ MF + +P +I  I N  KY   Y +    +HI+VCG     ++  FLK F  ++R      NV+IV ++    +  L    KR    +++  G++ N  DL RV I+ A   +IL+  +      +D  NIM  + +K+    +R I Q+  Y NK  L   P WN    D  +C+ ELKLG +A +CL  G++T++ NL +      + E  W+K Y  G+   +Y    S  F G+S   +  + Y    + L+AI+  +   +   LINP   ++K+  +  +   +A D     + +FYC  C    S   + + C C   E  ++   SP+   + N    N   N S +     P     SE+I+    +    D TG F+W P  + E V L    A    LS H++VC+ G +    I L NF+MPLR  N    EL+ IV +G+  Y + + W  + NFP   I+ G+P+   DLRA  +  C  CVI++ N   +      DK  I+ +  I+SM   + +++                     P+   +R+  +    +   I    NDS V              +  ++PFA G  F  S + S +   Y N +  + I+TL+ G  + E+E +      L      PQ  ++ +R      +   ++   P  ++    DG   Y  LF  AL    +LC G+YRL             RYV T+P  + E+  +D ++C +  D
Sbjct:  114 VMISAQTLTGRVL--VVLVFALSIGALVIYF----IDSSDPIEFCKHFYSNYTLQIDMAFNIFFLLYFGLRFIAANDKLWFWLEVNSVVDFFTVPPVFVSVYLNRSWLGLRFLRALRLIQFSEILQF-LNILKTSNSIKLVNLCSIFISTWLTAAGFIHLVENSGDPWENFQNSQALSYWECVYLLMVTMSTVGYGDVYAKTTLGRLFMVFFILGGLAMFASYVPEIIELIGNRKKYGGSYSAVNGRKHIVVCGHITLESVSNFLKDFLHKDR---DDVNVEIVFLHNISPNLELEALFKRHFTQVEFYQGSVLNPHDLARVKIESADACLILANKYCADPDAEDASNIMRVISIKNYHPKIRIITQMLQYHNKAHLLNIPSWNWKEGDDAICLAELKLGFIAQSCLAQGLSTMLANLFSMRSFIKIEEDTWQKYYLEGVSNEMYTEYLSSAFVGLSFPVICELCYVKLKLLLIAIEYKSDQRESSTLINPG-NHVKMQ-EGTLGFFIASDAKEVKRALFYCKACHDDISDPKRIKKCGCKKFEEDRHSALSPKKK-QRNGGMRNSP-NSSPKIMRHDPLFIPGSEQIESMDENVKKYDSTGMFHWCPSRDIEKVILTRSEAAMTVLSGHVVVCIFGDVKSALIGLRNFVMPLRASNFHYHELKHIVFVGSLEYLKRE-WETLHNFPKVSILPGTPLSRADLRAVNINLCDMCVILSANQNNIDDASLQDKECILASLNIKSMLFDDSIRVLQANSQGFTPPGMDRSSPENSPVHGLVRQTSVTTGANIPIITELVNDSNVQFLDQDDDDDPDTELYLTQPFACGTAFAVSVLDSLMSATYFNDNILTLIRTLVTGGATPELEGLLAEENALKGGYSTPQTLANRDRCR----VAQLALYDGPFADLG---DGGC-YGDLFCKALKTYNMLCFGIYRLRDAHLNAQSQCTKRYVITNPPYAFELVPSDLIFCLMQFD 1067

[Close]

BLAST of Calcium-activated potassium channel subunit alpha-1 vs. Ensembl Medaka
Match: kcnma1a (calcium-activated potassium channel subunit alpha-1 [Source:NCBI gene;Acc:101174692])

HSP 1 Score: 350.517 bits (898), Expect = 8.527e-103
Identity = 268/981 (27.32%), Postives = 450/981 (45.87%), Query Frame = 2

Query:  323 IMISKSTIVGRFLNFVKLISQLTSWGIFVVFTFNQVNANYLIGDCFDVEGANLQWIDFALNIFCLFHFTLRAFAANDILKFWIQPTTMIEITVIPNILLTSFLPVRRQGFSFLRIYYLRELCNTIAVSFGILKVNSKFEMTKVIFYIISLWLISAGLFHMFEGIGNFWEIPLFNQQLSFWRCCYFMLVTISTVGFGSVNPLTIFGRIVVLVYIIYGITMFVTVLPNVIRTIQNL-KYKNRYISKGNERHIIVCGKFESLTIIAFLKAF-KRERFKGSVRNVKIVTMNKDLYDENLLMYMKRFSNPIKYLIGNLSNRKDLKRVNIQKAKLSVILSTPFTNKISEDDIDNIMTAMILKSQRKNMRTIVQLHLYSNKVLLKMSPMWNQNRSDIILCIDELKLGLMAYNCLTPGIATLVINLVTFTKSKSVSE-LWRKDYENGLKVLLYNVQFSDCFHGMSCLEVALIVYKLWDVCLLAIKCVNKSTDDYVLINPMIENIKIDTDSMIAIVMARDEASSNKLIFYCSKCSPQ--NQSEICQCYLEATKNSPRGHYESNLQFENQRINESFRSAYE-FPTIDSKS-----------EEIDINSYTGLDRTGSFYWAPEPNFEDVCLDIETAESRSLSDHILVCLCG-IGHGTIDLCNFMMPLRFQNLQNSELRTIVILGNKSYFEADKWTNIKNFPMFLIIDGSPIQSRDLRAAGLLKCHTCVIINGNDKTV---GFSDKSAIICATLIRSMRKLNKLKI----------PIMIEIRKDEIAHHF----SSIHSHN---------NDSKV-------------SVQHSEPFARGILFTNSTVYSCIYTVYKNPDTFSFIKTLLNGRYSDEIESMFGSGVGL-----LPQXXXXXXXXXXXXIIKLFSVIQPPLNEISRVYDGILDYACLFEWALMEKRILCLGLYRLNFGR--------NRYVFTHPEKSTEIFSTDQVYCCVSSD 3055
            +MIS  T+ GR L  +     + + GI+ + + + + +     D F ++      ID A N+F L +F LR  AAND L FW++  ++++   +P + ++ +L     G  FLR   L +    +     ILK ++  ++  +    IS WL +AG  H+ E  G+ WE    +Q LS+W C Y ++VT+STVG+G V   T  GR+ ++ +I+ G+ MF + +P +I  I N  KY   Y +    +HI+VCG     ++  FLK F  ++R      NV+IV ++    +  L    KR    +++  G++ N  DL RV I+ A   +IL+  +      +D  NIM  + +K+    +R I Q+  Y NK  L   P WN    D  +C+ ELK G +A +CL  G++T++ NL +      + E  W+K Y  G+   +Y    S  F G+S   +  + Y    + L+AI+  ++  +  +LINP   ++K+  +  +   +A D     +  +YC  C     +   I +C  +  ++     + S L  + ++ N   R++    P + S+            E +D+N     D TG F+W P  + E V L    A    LS H++VC+ G +    + L N +MPLR  N    EL+ IV +G+  Y   + W  + NFP   I+ G+P+   DLRA  +  C  CVI++ N   +      DK  I+ +  I+SM+  + + +          P M     D    H     +S+ + +         NDS V              +  ++PFA G  F  S + S +   Y N +  + I+TL+ G  + E+E +      L      PQ  ++ +R      +   ++   P  ++    DG   Y  LF  AL    +LC G+YRL             RYV T+P    E+  +D ++C +  D
Sbjct:  144 VMISAQTLTGRVLVVLVFALSIGALGIYFIDSSDPIESCQSFYDDFTLQ------IDMAFNVFFLLYFGLRFIAANDKLWFWLEVNSVVDFFTVPPVFVSVYLNRSWLGLRFLRALRLIQFSEILQF-LNILKTSNSIKLVNLCSIFISTWLTAAGFIHLVENSGDPWENFQNSQSLSYWECVYLLMVTMSTVGYGDVYAKTTLGRLFMVFFILGGLAMFASYVPEIIELIGNRKKYGGSYSAVNGRKHIVVCGHITLESVSNFLKDFLHKDR---DDVNVEIVFLHNISPNLELEALFKRHFTQVEFYQGSVLNPHDLARVKIESADACLILANKYCGDPDAEDASNIMRVISIKNYHPKIRIITQMLQYHNKAHLLNIPSWNWKEGDDAICLAELKAGFIAQSCLAQGLSTMLANLFSMRSFIEIEEDTWQKYYLEGVANEMYTEYLSSAFVGLSFPHICELCYVKLKLLLIAIEYKSEQRESSILINPG-NHVKMQ-EGTLGFFIASDAKEVKRAFYYCKACHDDITDPKRIKKCGCKRLED----EHPSTLSPKKKQRNGGMRNSPNCSPKMMSRHDPLLIPGNEQIENMDMN-IKRYDSTGMFHWCPSKDIEKVILTRSEASMTVLSGHVVVCIFGDVTSALVGLRNLVMPLRASNFHYHELKPIVFVGSLDYLRRE-WETLHNFPKVSILPGTPLSRADLRAVNINLCDMCVILSANQNNIEDASLQDKECILASLNIKSMQFDDSIGVLQANSQGFTPPGMDRSSPDSSPVHGFVRQASVTTGSNIPIITELVNDSNVQFLDQDDDDDPDTELYLTQPFACGTAFAVSVLDSLMSATYFNDNILTLIRTLVTGGATPELEGLLAEENALRGGYSTPQTLANRDRCR----VAQLALYDGPFADLG---DGGC-YGDLFCKALKTYNMLCFGIYRLRDAHLGAPSQCTKRYVITNPPYEFELVPSDLIFCLMQFD 1098

[Close]

BLAST of Calcium-activated potassium channel subunit alpha-1 vs. Ensembl Medaka
Match: kcnma1a (calcium-activated potassium channel subunit alpha-1 [Source:NCBI gene;Acc:101174692])

HSP 1 Score: 339.732 bits (870), Expect = 1.053e-98
Identity = 270/1013 (26.65%), Postives = 449/1013 (44.32%), Query Frame = 2

Query:  323 IMISKSTIVGRFLNFVKLISQLTSWGIFVVFTFNQVNANYLIGDCFDVEGANLQWIDFALNIFCLFHFTLRAFAANDILKFWIQPTTMIEITVIPNILLTSFLPVRRQGFSFLRIYYLRELCNTIAVSFGILKVNSKFEMTKVIFYIISLWLISAGLFHMFEGIGNFWEIPLFNQQLSFWRCCYFMLVTISTVGFGSVNPLTIFGRIVVLVYIIYGITMFVTVLPNVIRTIQNL-KYKNRYISKGNERHIIVCGKFESLTIIAFLKAFKRERFKGSVRNVKIVTMNKDLYDENLLMYMKRFSNPIKYLIGNLSNRKDLKRVNIQKAKLSVILSTPFTNKISEDDIDNIMTAMILKSQRKNMRTIVQLHLYSNKVLLKMSPMWNQNRSDIILCIDELKLGLMAYNCLTPGIATLVINLVTFTKSKSVSE-LWRKDYENGLKVLLYNVQFSDCFHGMSCLEVALIVYKLWDVCLLAIKCVNKSTDD----YVLINPMIENIKIDTDSMIAIVMARDEASSNKLIFYCSKCSPQ--NQSEICQCYLEATKNSPRGHYESNLQFENQRINESFRSAYE-FPTIDSKS-----------EEIDINSYTGLDRTGSFYWAPEPNFEDVCLDIETAESRSLSDHILVCLCG-IGHGTIDLCNFMMPLRFQNLQNSELRTIVILGNKSYFEADKWTNIKNFPMFLIIDGSPIQSRDLRAAGLLKCHTCVIINGNDKTV---GFSDKSAIICATLIRSMRKLNKL--------------------------------------KIPIMIEIRKDEIAHHFSSIHSHNNDSKVSVQH---------------------------SEPFARGILFTNSTVYSCIYTVYKNPDTFSFIKTLLNGRYSDEIESMFGSGVGL-----LPQXXXXXXXXXXXXIIKLFSVIQPPLNEISRVYDGILDYACLFEWALMEKRILCLGLYRLNFGR--------NRYVFTHPEKSTEIFSTDQVYCCVSSD 3055
            +MIS  T+ GR L  +     + + GI+ + + + + +     D F ++      ID A N+F L +F LR  AAND L FW++  ++++   +P + ++ +L     G  FLR   L +    +     ILK ++  ++  +    IS WL +AG  H+ E  G+ WE    +Q LS+W C Y ++VT+STVG+G V   T  GR+ ++ +I+ G+ MF + +P +I  I N  KY   Y +    +HI+VCG     ++  FLK F   + +  V NV+IV ++    +  L    KR    +++  G++ N  DL RV I+ A   +IL+  +      +D  NIM  + +K+    +R I Q+  Y NK  L   P WN    D  +C+ ELK G +A +CL  G++T++ NL +      + E  W+K Y  G+   +Y    S  F G+S   +  + Y    + L+AI+  ++  +      +LINP   ++K+  +  +   +A D     +  +YC  C     +   I +C  +  ++     + S L  + ++ N   R++    P + S+            E +D+N     D TG F+W P  + E V L    A    LS H++VC+ G +    + L N +MPLR  N    EL+ IV +G+  Y   + W  + NFP   I+ G+P+   DLRA  +  C  CVI++ N   +      DK  I+ +  I+SM+  + +                                       IPI+ E+ K        S HS    S  S+Q                            ++PFA G  F  S + S +   Y N +  + I+TL+ G  + E+E +      L      PQ  ++ +R      +   ++   P  ++    DG   Y  LF  AL    +LC G+YRL             RYV T+P    E+  +D ++C +  D
Sbjct:  144 VMISAQTLTGRVLVVLVFALSIGALGIYFIDSSDPIESCQSFYDDFTLQ------IDMAFNVFFLLYFGLRFIAANDKLWFWLEVNSVVDFFTVPPVFVSVYLNRSWLGLRFLRALRLIQFSEILQF-LNILKTSNSIKLVNLCSIFISTWLTAAGFIHLVENSGDPWENFQNSQSLSYWECVYLLMVTMSTVGYGDVYAKTTLGRLFMVFFILGGLAMFASYVPEIIELIGNRKKYGGSYSAVNGRKHIVVCGHITLESVSNFLKDF-LHKDRDDV-NVEIVFLHNISPNLELEALFKRHFTQVEFYQGSVLNPHDLARVKIESADACLILANKYCGDPDAEDASNIMRVISIKNYHPKIRIITQMLQYHNKAHLLNIPSWNWKEGDDAICLAELKAGFIAQSCLAQGLSTMLANLFSMRSFIEIEEDTWQKYYLEGVANEMYTEYLSSAFVGLSFPHICELCYVKLKLLLIAIEYKSEQRESRSRKRILINPG-NHVKMQ-EGTLGFFIASDAKEVKRAFYYCKACHDDITDPKRIKKCGCKRLED----EHPSTLSPKKKQRNGGMRNSPNCSPKMMSRHDPLLIPGNEQIENMDMN-IKRYDSTGMFHWCPSKDIEKVILTRSEASMTVLSGHVVVCIFGDVTSALVGLRNLVMPLRASNFHYHELKPIVFVGSLDYLRRE-WETLHNFPKVSILPGTPLSRADLRAVNINLCDMCVILSANQNNIEDASLQDKECILASLNIKSMQFDDSIGVLQANSQGFTPPGMDRSSPDSSPVHGFVRQASVTTGSNIPIITELAKPGKLMPLVS-HSQEKKSGTSIQMITELVNDSNVQFLDQDDDDDPDTELYLTQPFACGTAFAVSVLDSLMSATYFNDNILTLIRTLVTGGATPELEGLLAEENALRGGYSTPQTLANRDRCR----VAQLALYDGPFADLG---DGGC-YGDLFCKALKTYNMLCFGIYRLRDAHLGAPSQCTKRYVITNPPYEFELVPSDLIFCLMQFD 1130

[Close]

BLAST of Calcium-activated potassium channel subunit alpha-1 vs. Ensembl Medaka
Match: kcnma1a (calcium-activated potassium channel subunit alpha-1 [Source:NCBI gene;Acc:101174692])

HSP 1 Score: 339.347 bits (869), Expect = 1.292e-98
Identity = 270/1008 (26.79%), Postives = 452/1008 (44.84%), Query Frame = 2

Query:  323 IMISKSTIVGRFLNFVKLISQLTSWGIFVVFTFNQVNANYLIGDCFDVEGANLQWIDFALNIFCLFHFTLRAFAANDILKFWIQPTTMIEITVIPNILLTSFLPVRRQGFSFLRIYYLRELCNTIAVSFGILKVNSKFEMTKVIFYIISLWLISAGLFHMFEGIGNFWEIPLFNQQLSFWRCCYFMLVTISTVGFGSVNPLTIFGRIVVLVYIIYGITMFVTVLPNVIRTIQNL-KYKNRYISKGNERHIIVCGKFESLTIIAFLKAF-KRERFKGSVRNVKIVTMNKDLYDENLLMYMKRFSNPIKYLIGNLSNRKDLKRVNIQKAKLSVILSTPFTNKISEDDIDNIMTAMILKSQRKNMRTIVQLHLYSNKVLLKMSPMWNQNRSDIILCIDELKLGLMAYNCLTPGIATLVINLVTFTKSKSVSE-LWRKDYENGLKVLLYNVQFSDCFHGMSCLEVALIVYKLWDVCLLAIKCVNKSTDD----YVLINPMIENIKIDTDSMIAIVMARDEASSNKLIFYCSKC----SPQNQSEICQCYLEATKNSPRGH---------------------YESNLQFENQRINESFRSAYE-FPTIDSKS-----------EEIDINSYTGLDRTGSFYWAPEPNFEDVCLDIETAESRSLSDHILVCLCG-IGHGTIDLCNFMMPLRFQNLQNSELRTIVILGNKSYFEADKWTNIKNFPMFLIIDGSPIQSRDLRAAGLLKCHTCVIINGNDKTV---GFSDKSAIICATLIRSMRKLNKLKI----------PIMIEIRKDEIAHHF----SSIHSHN---------NDSKV-------------SVQHSEPFARGILFTNSTVYSCIYTVYKNPDTFSFIKTLLNGRYSDEIESMFGSGVGL-----LPQXXXXXXXXXXXXIIKLFSVIQPPLNEISRVYDGILDYACLFEWALMEKRILCLGLYRLNFGR--------NRYVFTHPEKSTEIFSTDQVYCCVSSD 3055
            +MIS  T+ GR L  +     + + GI+ + + + + +     D F ++      ID A N+F L +F LR  AAND L FW++  ++++   +P + ++ +L     G  FLR   L +    +     ILK ++  ++  +    IS WL +AG  H+ E  G+ WE    +Q LS+W C Y ++VT+STVG+G V   T  GR+ ++ +I+ G+ MF + +P +I  I N  KY   Y +    +HI+VCG     ++  FLK F  ++R      NV+IV ++    +  L    KR    +++  G++ N  DL RV I+ A   +IL+  +      +D  NIM  + +K+    +R I Q+  Y NK  L   P WN    D  +C+ ELK G +A +CL  G++T++ NL +      + E  W+K Y  G+   +Y    S  F G+S   +  + Y    + L+AI+  ++  +      +LINP   ++K+  +  +   +A D     +  +YC  C    +   + + C C   A   +  G+                     + S L  + ++ N   R++    P + S+            E +D+N     D TG F+W P  + E V L    A    LS H++VC+ G +    + L N +MPLR  N    EL+ IV +G+  Y   + W  + NFP   I+ G+P+   DLRA  +  C  CVI++ N   +      DK  I+ +  I+SM+  + + +          P M     D    H     +S+ + +         NDS V              +  ++PFA G  F  S + S +   Y N +  + I+TL+ G  + E+E +      L      PQ  ++ +R      +   ++   P  ++    DG   Y  LF  AL    +LC G+YRL             RYV T+P    E+  +D ++C +  D
Sbjct:  144 VMISAQTLTGRVLVVLVFALSIGALGIYFIDSSDPIESCQSFYDDFTLQ------IDMAFNVFFLLYFGLRFIAANDKLWFWLEVNSVVDFFTVPPVFVSVYLNRSWLGLRFLRALRLIQFSEILQF-LNILKTSNSIKLVNLCSIFISTWLTAAGFIHLVENSGDPWENFQNSQSLSYWECVYLLMVTMSTVGYGDVYAKTTLGRLFMVFFILGGLAMFASYVPEIIELIGNRKKYGGSYSAVNGRKHIVVCGHITLESVSNFLKDFLHKDR---DDVNVEIVFLHNISPNLELEALFKRHFTQVEFYQGSVLNPHDLARVKIESADACLILANKYCGDPDAEDASNIMRVISIKNYHPKIRIITQMLQYHNKAHLLNIPSWNWKEGDDAICLAELKAGFIAQSCLAQGLSTMLANLFSMRSFIEIEEDTWQKYYLEGVANEMYTEYLSSAFVGLSFPHICELCYVKLKLLLIAIEYKSEQRESRSRKRILINPG-NHVKMQ-EGTLGFFIASDAKEVKRAFYYCKACHDDITDPKRIKKCGCKRPAEGATTPGNTGSQKEAGVRFKADCNIVEDEHPSTLSPKKKQRNGGMRNSPNCSPKMMSRHDPLLIPGNEQIENMDMN-IKRYDSTGMFHWCPSKDIEKVILTRSEASMTVLSGHVVVCIFGDVTSALVGLRNLVMPLRASNFHYHELKPIVFVGSLDYLRRE-WETLHNFPKVSILPGTPLSRADLRAVNINLCDMCVILSANQNNIEDASLQDKECILASLNIKSMQFDDSIGVLQANSQGFTPPGMDRSSPDSSPVHGFVRQASVTTGSNIPIITELVNDSNVQFLDQDDDDDPDTELYLTQPFACGTAFAVSVLDSLMSATYFNDNILTLIRTLVTGGATPELEGLLAEENALRGGYSTPQTLANRDRCR----VAQLALYDGPFADLG---DGGC-YGDLFCKALKTYNMLCFGIYRLRDAHLGAPSQCTKRYVITNPPYEFELVPSDLIFCLMQFD 1129

[Close]

BLAST of Calcium-activated potassium channel subunit alpha-1 vs. Ensembl Medaka
Match: kcnma1a (calcium-activated potassium channel subunit alpha-1 [Source:NCBI gene;Acc:101174692])

HSP 1 Score: 321.627 bits (823), Expect = 1.301e-92
Identity = 261/981 (26.61%), Postives = 438/981 (44.65%), Query Frame = 2

Query:  323 IMISKSTIVGRFLNFVKLISQLTSWGIFVVFTFNQVNANYLIGDCFDVEGANLQWIDFALNIFCLFHFTLRAFAANDILKFWIQPTTMIEITVIPNILLTSFLPVRRQGFSFLRIYYLRELCNTIAVSFGILKVNSKFEMTKVIFYIISLWLISAGLFHMFEGIGNFWEIPLFNQQLSFWRCCYFMLVTISTVGFGSVNPLTIFGRIVVLVYIIYGITMFVTVLPNVIRTIQNL-KYKNRYISKGNERHIIVCGKFESLTIIAFLKAF-KRERFKGSVRNVKIVTMNKDLYDENLLMYMKRFSNPIKYLIGNLSNRKDLKRVNIQKAKLSVILSTPFTNKISEDDIDNIMTAMILKSQRKNMRTIVQLHLYSNKVLLKMSPMWNQNRSDIILCIDELKLGLMAYNCLTPGIATLVINLVTFTKSKSVSE-LWRKDYENGLKVLLYNVQFSDCFHGMSCLEVALIVYKLWDVCLLAIKCVNKSTDDYVLINPMIENIKIDTDSMIAIVMARDEASSNKLIFYCSKCSPQ--NQSEICQCYLEATKNSPRGHYESNLQFENQRINESFRSAYE-FPTIDSKS-----------EEIDINSYTGLDRTGSFYWAPEPNFEDVCLDIETAESRSLSDHILVCLCG-IGHGTIDLCNFMMPLRFQNLQNSELRTIVILGNKSYFEADKWTNIKNFPMFLIIDGSPIQSRDLRAAGLLKCHTCVIINGNDKTV---GFSDKSAIICATLIRSMRKLNKLKI----------PIMIEIRKDEIAHHF----SSIHSHN---------NDSKV-------------SVQHSEPFARGILFTNSTVYSCIYTVYKNPDTFSFIKTLLNGRYSDEIESMFGSGVGL-----LPQXXXXXXXXXXXXIIKLFSVIQPPLNEISRVYDGILDYACLFEWALMEKRILCLGLYRLNFGR--------NRYVFTHPEKSTEIFSTDQVYCCVSSD 3055
            +MIS  T+ GR L  +     + + GI+ + + + + +     D F ++      ID A N+F L +F LR  AAND L FW++  ++++   +P + ++ +L     G  FLR   L +    +     ILK ++  ++  +    IS WL +AG  H+ E  G+ WE    +Q LS+W C Y ++VT+STVG+G V   T  GR+ ++ +I+ G+ MF   +P +   I N  KY   Y S    +HI+VCG     ++  FLK F  ++R      NV+IV ++    +  L    KR    +++  G++ N  DL RV I+ A   +IL+  +      +D  NIM                +  LY          +WN    D  +C+ ELK G +A +CL  G++T++ NL +      + E  W+K Y  G+   +Y    S  F G+S   +  + Y    + L+AI+  ++  +  +LINP   ++K+  +  +   +A D     +  +YC  C     +   I +C  +  ++     + S L  + ++ N   R++    P + S+            E +D+N     D TG F+W P  + E V L    A    LS H++VC+ G +    + L N +MPLR  N    EL+ IV +G+  Y   + W  + NFP   I+ G+P+   DLRA  +  C  CVI++ N   +      DK  I+ +  I+SM+  + + +          P M     D    H     +S+ + +         NDS V              +  ++PFA G  F  S + S +   Y N +  + I+TL+ G  + E+E +      L      PQ  ++ +R      +   ++   P  ++    DG   Y  LF  AL    +LC G+YRL             RYV T+P    E+  +D ++C +  D
Sbjct:  144 VMISAQTLTGRVLVVLVFALSIGALGIYFIDSSDPIESCQSFYDDFTLQ------IDMAFNVFFLLYFGLRFIAANDKLWFWLEVNSVVDFFTVPPVFVSVYLNRSWLGLRFLRALRLIQFSEILQF-LNILKTSNSIKLVNLCSIFISTWLTAAGFIHLVENSGDPWENFQNSQSLSYWECVYLLMVTMSTVGYGDVYAKTTLGRLFMVFFILGGLAMFARYVPEIAALILNRKKYGGSYNSTRGRKHIVVCGHITLESVSNFLKDFLHKDR---DDVNVEIVFLHNISPNLELEALFKRHFTQVEFYQGSVLNPHDLARVKIESADACLILANKYCGDPDAEDASNIM----------------RYTLYH---------IWNWKEGDDAICLAELKAGFIAQSCLAQGLSTMLANLFSMRSFIEIEEDTWQKYYLEGVANEMYTEYLSSAFVGLSFPHICELCYVKLKLLLIAIEYKSEQRESSILINPG-NHVKMQ-EGTLGFFIASDAKEVKRAFYYCKACHDDITDPKRIKKCGCKRLED----EHPSTLSPKKKQRNGGMRNSPNCSPKMMSRHDPLLIPGNEQIENMDMN-IKRYDSTGMFHWCPSKDIEKVILTRSEASMTVLSGHVVVCIFGDVTSALVGLRNLVMPLRASNFHYHELKPIVFVGSLDYLRRE-WETLHNFPKVSILPGTPLSRADLRAVNINLCDMCVILSANQNNIEDASLQDKECILASLNIKSMQFDDSIGVLQANSQGFTPPGMDRSSPDSSPVHGFVRQASVTTGSNIPIITELVNDSNVQFLDQDDDDDPDTELYLTQPFACGTAFAVSVLDSLMSATYFNDNILTLIRTLVTGGATPELEGLLAEENALRGGYSTPQTLANRDRCR----VAQLALYDGPFADLG---DGGC-YGDLFCKALKTYNMLCFGIYRLRDAHLGAPSQCTKRYVITNPPYEFELVPSDLIFCLMQFD 1073

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BLAST of Calcium-activated potassium channel subunit alpha-1 vs. Planmine SMEST
Match: SMESG000040067.1 (SMESG000040067.1)

HSP 1 Score: 1961.04 bits (5079), Expect = 0.000e+0
Identity = 1006/1014 (99.21%), Postives = 1010/1014 (99.61%), Query Frame = 2

Query:   29 MNSSKQSVGCDTDILWWVSYSISVAIFICGFMIIGISNCVNIIREILGXXXXXXXXXXXRRTRITIXXXXXXXXXXXXXXXXXXXXISSKLNFLSFCEIMISKSTIVGRFLNFVKLISQLTSWGIFVVFTFNQVNANYLIGDCFDVEGANLQWIDFALNIFCLFHFTLRAFAANDILKFWIQPTTMIEITVIPNILLTSFLPVRRQGFSFLRIYYLRELCNTIAVSFGILKVNSKFEMTKVIFYIISLWLISAGLFHMFEGIGNFWEIPLFNQQLSFWRCCYFMLVTISTVGFGSVNPLTIFGRIVVLVYIIYGITMFVTVLPNVIRTIQNLKYKNRYISKGNERHIIVCGKFESLTIIAFLKAFKRERFKGSVRNVKIVTMNKDLYDENLLMYMKRFSNPIKYLIGNLSNRKDLKRVNIQKAKLSVILSTPFTNKISEDDIDNIMTAMILKSQRKNMRTIVQLHLYSNKVLLKMSPMWNQNRSDIILCIDELKLGLMAYNCLTPGIATLVINLVTFTKSKSVSELWRKDYENGLKVLLYNVQFSDCFHGMSCLEVALIVYKLWDVCLLAIKCVNKSTDDYVLINPMIENIKIDTDSMIAIVMARDEASSNKLIFYCSKCSPQNQSEICQCYLEATKNSPRGHYESNLQFENQRINESFRSAYEFPTIDSKSEEIDINSYTGLDRTGSFYWAPEPNFEDVCLDIETAESRSLSDHILVCLCGIGHGTIDLCNFMMPLRFQNLQNSELRTIVILGNKSYFEADKWTNIKNFPMFLIIDGSPIQSRDLRAAGLLKCHTCVIINGNDKTVGFSDKSAIICATLIRSMRKLNKLKIPIMIEIRKDEIAHHFSSIHSHNNDSKVSVQHSEPFARGILFTNSTVYSCIYTVYKNPDTFSFIKTLLNGRYSDEIESMFGSGVGLLPQXXXXXXXXXXXXIIKLFSVIQPPLNEISRVYDGILDYACLFEWALMEKRILCLGLYRLNFGRNRYVFTHPEKSTEIFSTDQVYCCVSSDFFNTL 3070
            MNSSKQSVGCDTDILWWVSYSISVAIFICGFMIIGISNCVNIIREILGKKKKKMEAMKKRRTRITIFENNFPTNNNYNSNVNSLFSISS LNFLSFCEI+ISKSTIVGRFLNFVKLISQLTSWGIFVVFTFNQVNANYLIGDCFDVEGANLQWIDFALNIFCLFHFTLRAFAANDILKFWIQPTTMIEITVIPNILLTSFLPVRRQGFSFLRIYYLRELCNTIAVSFGI KVNSKFEMTKVIFYIISLWLISAGLFHMFEGIGNFWEIPLFNQQLSFWRCCYFMLVTISTVGFGSVNPLTIFGRIVVLVYIIYGITMFVTVLPNVIRTIQNLKYKNRYISKGNERHIIVCGKFESLTIIAFLKAFKRERFKGSVRNVKIVTMNKDLYDENLLMYMKRFSNPIKYLIGNLSNRKDLKRVNIQKAKLSVILSTPFTNKISEDDIDNIMTAMILKSQRKNMRTIVQLHLYSNKVLLKMSPMWNQNRSDIILCIDELKLGLMAYNCLTPGIATLVINLVTFTKSKS SELWRKDYENGLKVLLYNVQFSDCFHGMSCLEVALIVYKLWDVCLLAIKCVNKSTDDYVLINPMIENIKIDTDSMIAIVMARDEASSNKL+FYCSKCSPQN SEICQCYLEATKNSPRGHYESN+QFENQRINESFRSAYEFPTIDSKSEEID+NSYTGLDRTGSFYWAPEPNFEDVCLDIETAESRSLSDHILVCLCGIGHGTIDLCNFMMPLRFQNLQNSELRTIVILGNKSYFEADKWTNIKNFPMFLIIDGSPIQSRDLRAAGLLKCHTCVIINGNDKTVGFSDKSAIICATLIRSMRKLNKLKIPIMIEIRKDEIAHHFSSIHSHNNDSKVSVQHSEPFARGILFTNSTVYSCIYTVYKNPDTFSFIKTLLNGRYSDEIESMFGSGVGLLPQNSSSENRENSNSIIKLFSVIQPPLNEISRVYDGILDYACLFEWALMEKRILCLGLYRLNFGRNRYVFTHPEKSTEIFSTDQVYCCVSSDFFNTL
Sbjct:    1 MNSSKQSVGCDTDILWWVSYSISVAIFICGFMIIGISNCVNIIREILGKKKKKMEAMKKRRTRITIFENNFPTNNNYNSNVNSLFSISSNLNFLSFCEIIISKSTIVGRFLNFVKLISQLTSWGIFVVFTFNQVNANYLIGDCFDVEGANLQWIDFALNIFCLFHFTLRAFAANDILKFWIQPTTMIEITVIPNILLTSFLPVRRQGFSFLRIYYLRELCNTIAVSFGIFKVNSKFEMTKVIFYIISLWLISAGLFHMFEGIGNFWEIPLFNQQLSFWRCCYFMLVTISTVGFGSVNPLTIFGRIVVLVYIIYGITMFVTVLPNVIRTIQNLKYKNRYISKGNERHIIVCGKFESLTIIAFLKAFKRERFKGSVRNVKIVTMNKDLYDENLLMYMKRFSNPIKYLIGNLSNRKDLKRVNIQKAKLSVILSTPFTNKISEDDIDNIMTAMILKSQRKNMRTIVQLHLYSNKVLLKMSPMWNQNRSDIILCIDELKLGLMAYNCLTPGIATLVINLVTFTKSKSFSELWRKDYENGLKVLLYNVQFSDCFHGMSCLEVALIVYKLWDVCLLAIKCVNKSTDDYVLINPMIENIKIDTDSMIAIVMARDEASSNKLVFYCSKCSPQNLSEICQCYLEATKNSPRGHYESNVQFENQRINESFRSAYEFPTIDSKSEEIDMNSYTGLDRTGSFYWAPEPNFEDVCLDIETAESRSLSDHILVCLCGIGHGTIDLCNFMMPLRFQNLQNSELRTIVILGNKSYFEADKWTNIKNFPMFLIIDGSPIQSRDLRAAGLLKCHTCVIINGNDKTVGFSDKSAIICATLIRSMRKLNKLKIPIMIEIRKDEIAHHFSSIHSHNNDSKVSVQHSEPFARGILFTNSTVYSCIYTVYKNPDTFSFIKTLLNGRYSDEIESMFGSGVGLLPQNSSSENRENSNSIIKLFSVIQPPLNEISRVYDGILDYACLFEWALMEKRILCLGLYRLNFGRNRYVFTHPEKSTEIFSTDQVYCCVSSDFFNTL 1014

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BLAST of Calcium-activated potassium channel subunit alpha-1 vs. Planmine SMEST
Match: SMESG000040071.1 (SMESG000040071.1)

HSP 1 Score: 980.704 bits (2534), Expect = 0.000e+0
Identity = 486/1018 (47.74%), Postives = 694/1018 (68.17%), Query Frame = 2

Query:   29 MNSSKQSVGC-DTDILWWVSYSISVAIFICGFMIIGISNC-VNIIREILGXXXXXXXXXXXRRTRITIXXXXXXXXXXXXXXXXXXXXISSK--LNFLSFCEIMISKSTIVGRFLNFVKLISQLTSWGIFVVFTFNQVNANYLIGDCFDVEGANLQWIDFALNIFCLFHFTLRAFAANDILKFWIQPTTMIEITVIPNILLTSFLPVRRQGFSFLRIYYLRELCNTIAVSFGILKVNSKFEMTKVIFYIISLWLISAGLFHMFEGIGNFWEIPLFNQQLSFWRCCYFMLVTISTVGFGSVNPLTIFGRIVVLVYIIYGITMFVTVLPNVIRTIQNLKYKNRYISKGNERHIIVCGKFESLTIIAFLKAFKRERFKGSVRNVKIVTMNKDLYDENLLMYMKRFSNPIKYLIGNLSNRKDLKRVNIQKAKLSVILSTPFTNKISEDDIDNIMTAMILKSQRKNMRTIVQLHLYSNKVLLKMSPMWNQNRSDIILCIDELKLGLMAYNCLTPGIATLVINLVTFTKSKSVSELWRKDYENGLKVLLYNVQFSDCFHGMSCLEVALIVYKLWDVCLLAIKCVNKSTDDYVLINPMIENIKIDTDSMIAIVMARDEASSNKLIFYCSKCSPQNQSEICQCYLEATKNSPRGHYESNLQFENQRINESFRSAYEFPTIDSKSEEIDINSYT-GLDRTGSFYWAPEPNFEDVCLDIETAESRSLSDHILVCLCGIGHGTIDLCNFMMPLRFQNLQNSELRTIVILGNKSYFEADKWTNIKNFPMFLIIDGSPIQSRDLRAAGLLKCHTCVIINGNDKTVGFSDKSAIICATLIRSMRKLNKLKIPIMIEIRKDEIAHHFSSIHSHNNDSKVSVQHSEPFARGILFTNSTVYSCIYTVYKNPDTFSFIKTLLNGRYSDEIESMFGSGVGLLPQXXXXXXXXXXXXIIKLFSVIQPPLNEISRVYDGILDYACLFEWALMEKRILCLGLYRLNFGRNRYVFTHPEKSTEIFSTDQVYCCVSSDFFNT 3067
            MN+S  S+G   T   WW++Y+IS+ IF  GF+IIGI    V + R     K      M +R++R+ +       +++++  +     ++S   + F  +CE + S+ + +GR      +I  L SW I++ FT+ Q   +YL GD +  +    +WIDF LN+F   HF  RAFAA DI+KFWI P T+I+I  IPN+ +++FLPVRRQG SFLRIYY+R L + I V+FG++K+ SK ++  +  Y++S+W+I +G  HM E  G+ W      Q  SFW   YF+L T+STVG+G  NP T+ G+++V +YIIY IT+F T LP +   I++ KY  +YI++  E+H+IV G+F + T+  FLK F  +R +   RN+KI+ MN    D  L +Y+K+FS+ I YL+G++    D++RV++ KAK   ILS P+TNKI +DD +NIMTA+ LK+Q + +RTIVQLHLYSNK+LLKM P WN+ ++D+++C+DEL+LGLMAYNCL PG+ATLV NL+T T+      LWRK+YE GL+  LYNV+FSD FHGM CL+VA+I+YKLWDVCLLAIK V     + V INPM EN+KIDT SMI IVMARDE+ + ++ ++CSKCS  +   IC C ++ +  +     + + + +++R+++  +S+Y F  +DS   +ID  + T  +D T +F+WA  P  +++C+D+  AE R  S+HIL+CLCG G GTIDLCNFMMPLRF++L    LR IVILGNK YFE  KW+NIKNFP F+I+ GSPIQ+RD+RAAGL  C++C ++NGND     SDK ++ICATLIRSM   ++ +  ++ EIR+DE+A HFSS+ + + D+K+ VQHSEPFA G+LFTNS +Y CIY++Y NPDTFSF+  L+NG   + +E MFG GVGL+P+   S     ++ + +L  +     + +  +++G L Y  LFEWAL +K ILCLGLYRLNFG+ RYV+THP+KSTEI  TD+VYC + ++   T
Sbjct:    1 MNTSLVSLGTLSTSYPWWLTYTISLGIFGLGFIIIGIMQIGVKMNRH---TKPSLKINMLRRKSRLLMNTAMGECDSDFDEWIEDDIGMTSSKFIEFSLWCERITSQRSSIGRISCLFLVILNLLSWSIYIGFTYYQTTTSYLEGDFYSAKMMIPKWIDFGLNVFFALHFIFRAFAAMDIIKFWILPATLIDICAIPNVFISTFLPVRRQGMSFLRIYYIRYLYDVIFVNFGLVKITSKTKIFNLSLYLVSVWMIGSGFIHMEENTGDIWLDNNPKQNWSFWISTYFLLETVSTVGYGDYNPQTVSGQVIVCIYIIYAITLFATALPEIFYAIKDSKYNEKYITRSGEKHMIVTGQFINSTMKTFLKVFINKRTRKQFRNMKIIIMNNQPCDRVLSLYLKKFSSFIMYLMGSIQQISDMERVDLHKAKTIFILSLPYTNKIYDDDSENIMTAISLKAQEERIRTIVQLHLYSNKILLKMFPRWNKYKNDVVVCLDELRLGLMAYNCLVPGMATLVTNLMTCTEPMKTHNLWRKEYEEGLENRLYNVEFSDDFHGMPCLDVAIILYKLWDVCLLAIKNVKNDYLNSVTINPMAENVKIDTLSMIGIVMARDESHARRISYFCSKCSYTDSFTICNCQMQPSTKNNFDLKKVHNRMKSKRLSQISKSSYLFSLMDSNPYKIDSGTLTENIDETETFFWAVTPKLDEICIDVRQAEKRKFSNHILLCLCGSGEGTIDLCNFMMPLRFRSLTWENLRQIVILGNKKYFEGHKWSNIKNFPKFIIVHGSPIQARDVRAAGLFDCYSCAVLNGNDDVNETSDKQSLICATLIRSMLADHRPEFSLITEIREDEVACHFSSVEAFDIDNKMPVQHSEPFAGGLLFTNSILYRCIYSIYHNPDTFSFVSALINGSRGELVEKMFGCGVGLIPKKVVSLENHVADVVFQLVPINDNLFHNVPNLHEGNLTYEILFEWALQKKHILCLGLYRLNFGKRRYVYTHPKKSTEILMTDKVYCTLVNNSIRT 1015

[Close]

BLAST of Calcium-activated potassium channel subunit alpha-1 vs. Planmine SMEST
Match: SMESG000050831.1 (SMESG000050831.1)

HSP 1 Score: 317.775 bits (813), Expect = 9.331e-92
Identity = 269/947 (28.41%), Postives = 444/947 (46.88%), Query Frame = 2

Query:  482 QWIDFALNIFCLFHFTLRAFAANDILKFWIQPTTMIEITVIPNILLTSFLPVRRQGFSFLRIYYLRELCNTIAVSFGILKVNSKFEMTKVIFYIISLWLISAGLFHMFEGIGNFWEIPLF---NQQLSFWRCCYFMLVTISTVGFGSVNPLTIFGRIVVLVYIIYGITMFVTVLPNVIRTIQNL-KYKNRYISKGNERHIIVCGKFESLTIIAFLKAFKRERFKGSVRNVKIVTMNKDLYDENLLMYMKRFSNPIKYLIGNLSNRKDLKRVNIQKAKLSVILSTPFTNKISEDDIDNIMTAMILKSQRKNMRTIVQLHLYSNKVLLKMSPMWNQNRSDIILCIDELKLGLMAYNCLTPGIATLVINLVTFTKSKSVSEL--WRKDYENGLKVLLYNVQFSDCFHGMSCLEVALIVYKLWDVCLLAIKCVNKST---DDYVLINPMIENIKIDTDSMIAIVMARDEASSNKLIFYCSKCSPQNQSE-ICQCYLEATKNSPRGHYE---------SNLQFENQRINESF-----RSAYEFPTIDSKSEEI-DINSYTGL----------DRTGSFYWAPEPNFEDVCL-DIETAESRSLSDHILVCLCGIGHGT-IDLCNFMMPLRFQNLQNSELRTIVILGNKSYFEADKWTNIKNFPMFLIIDGSPIQSRDLRAAGLLKCHTCVII----NGNDKTVGFSDKSAIICATLIRSMR-KLNKLKI---PIMIEIRKDEIAHHFSSIHSHNNDSKVS-----------------VQH---------------SEPFARGILFTNSTVYSCIYTVYKNPDTFSFIKTLLNGRYSDEIESMFGSGVGLLPQXXXXXXXXXXXXI-IKLFSVIQPPLNEISRVYDGILDYACLFEWALMEKRILCLGLYRL---------NFG-------RNRYVFTHPEKSTEIFSTDQVYC 3040
            Q +D A NI  L +F LR  A+ND L FW++  + +++  IP   +  +L     G  F+R   L  L + +     ++K +S   +  +    +SL + ++G  H+ E  G     P+     Q  +F    YF++VTISTVG+G +   T  G+++++ +I+ G+ +F   +P +I  I +  +Y+N +  + +++HII+CG     ++  FL  F  +  +    +VKIV +N    +  L   +KR+   +++  G+  N  DL R+ +Q A   ++L+  ++     +D  NIM  + +K+    ++ IVQL  Y NK  L   P W+  R D  +C+ ELKLG +A +CL PG +TL+ NL T    K+ + L  W   Y  G  + +Y+  FS  FHG +  E   + +K   + L+AI+   KST   ++ + INP   +IKI+   M    +A+    S +  F+C KC      + I QC   A K      ++          + + E+++ +ES      R+    P    +   I +  S+ GL          D TG F+W PE   EDV L D +  +    S+HI+VC+    +   I LCNF+MPLR  N   SEL  IV +GN  Y + + W ++ NFP   I+ GS +   +LRA  +     CVI+    N +       DK AI+C+  +++M   ++  K+   P ++      +++    +     D K+S                 VQ                ++PFA G  F  S + S + T Y N +  + I+TL+ G  + ++E +   G G+     + +   N +   + +  V Q PL EI    +G  +Y  LF  AL    ILC+GLYRL         N G       + RYV T+P    +I  +D VYC
Sbjct:  149 QQLDLAFNIIFLVYFFLRFLASNDKLCFWLELYSFVDLYTIPPSFVILYLGRYWIGLRFVRAMRLMTLSDVLGF-LNVIKSSSSIRLCHLFTTFVSLVITASGFIHLVESSGG----PVIADNGQNRNFLDFTYFIIVTISTVGYGDIVCRTPTGKLMMMFFILGGLALFANSIPEMIEIIGSRNRYRNPFRKQKDKQHIILCGHITYDSVSNFLADFLHKDREDV--DVKIVILNNFPPELELKNVLKRYFIHVEFYQGSGMNSNDLSRIQLQNADACLVLANKYSPDPDAEDAANIMRVISIKNFCPRIKVIVQLMQYHNKAYLLNIPSWDWKRGDDAVCLAELKLGFIAQSCLAPGFSTLLANLFTMRSFKNDANLPNWLNTYLEGAGMEMYSEYFSPAFHGCTFAEAVAMSFKYLKLLLIAIE--TKSTVNEENSIAINPK-NDIKIEP-GMQGFFIAQSADESKRAFFFCRKCHLNRHYKYIKQCSCAAHKQFQNTLHKLRKFETTKSRHSKLESKKGDESSKVKLRRNRNIRPNERKRPHNIRNQKSFRGLRFNEQISRRFDTTGMFHWCPERPIEDVLLNDSDQLKMCVFSNHIVVCVFAESNSALIGLCNFVMPLRASNFHYSELSYIVFIGNLEYLKRE-WKSLANFPCLSILSGSSLSRTNLRAVNVNMSKMCVILSSKSNNSMDDAFLVDKEAILCSLNVQAMSFDIDSFKMENFPELLPQISKSVSYSSFGMEKDMTDDKISKSGADIKMITELAIDSNVQFLDQDDEDSPETELFMTQPFACGRAFAVSVLDSLMSTAYFNENALTLIRTLITGGATPDLEQVLAEGCGIQGAYLTPDTLGNRDRCRVTIIQVTQNPLAEIFISKNGGCNYGHLFLEALERFGILCIGLYRLINLDNLVNDNAGMMLNTNSKKRYVITNPPDFLQIHYSDMVYC 1083

[Close]

BLAST of Calcium-activated potassium channel subunit alpha-1 vs. Planmine SMEST
Match: SMESG000076792.1 (SMESG000076792.1)

HSP 1 Score: 268.47 bits (685), Expect = 1.060e-74
Identity = 245/985 (24.87%), Postives = 426/985 (43.25%), Query Frame = 2

Query:  326 MISKSTIVGRFLNFVKLISQLTSWGIFVVFTFNQVNANYLIGD--CFDVEGANLQWIDFALNIFCLFHFTLRAFAANDILKFWIQPTTMIEITVIPNILLTSFLPVRRQGFSFLRIYYLRELCNTIAVSFGILKVNSKFEMTKVIFYIISLWLISAGLFHMFEGIGNFWEIPLFNQQLSFWRCCYFMLVTISTVGFGSVNPLTIFGRIVVLVYIIYGITMFVTVLPNVIRTIQNL-KYKNRYISKGNERHIIVCGKFESLTIIAFLKAFKRERFKGSVRNVKIVTMNKDLYDENLLMYMKRFSNPIKYLIGNLSNRK-DLKRVNIQKAKLSVILSTPFTNKISEDDIDNIMTAMILKSQRKNMRTIVQLHLYSNKVLLKMSPMWNQNRSDIILCIDELKLGLMAYNCLTPGIATLVINLVTFTKSKSVSEL--WRKDYENGLKVLLYNVQFSDCFHGMSCLEVALIVYKLWDVCLLAIKCVNKSTDDY---VLINPMIENIKIDTDSMIAIVMARDEASSNKLIFYCSKCSPQNQS-----------------EICQCYLEATKNSPRGHYESNLQFENQRINESFRSAYEFPTIDSKSEEIDI---------NSYTGLDRTGSFYWAPEPNFEDVCL-DIETAESRSLSDHILVCLCGIGHGT-IDLCNFMMPLRFQNLQNSELRTIVILGNKSYFEADKWTNIKNFPMFLIIDGSPIQSRDLRAAGLLKCHTCVIINGNDKT----VGFSDKSAIICATLIRSM---------RKLNKL-------------KIPIMIEIRKDEIAHHFSSIHSHNNDSKVSVQHSEPFARGILFTNSTVYSCIYTVYKNPDTFSFIKTLLNGRYSDEIESMFG-----SGVGLLPQXXXXXXXXXXXXIIKLFSVIQPPLNEISRVYDGILDYACLFEWALMEKRILCLGLYRL------------NFGRNRYVFTHPEKSTEIFSTDQVYC 3040
            +IS     GR L  + ++S L S G  +++ F +++    + D  C     +  Q  D A NI  L  F LR  AA D   FWI+  +++++  +P   +T  L     G  F R   L    + + V   ILK +SK  +  ++    SL L SAG  H+ E  G+  E     Q  +++   YFM+ T+STVG+G +   T  G+++++ +I+ G+ +F   +P +I  I N  +Y   +  +  ++HII+CG             F+R        + +                         Y I     +K    RV ++ A   +IL   ++     +D  NIM  + +K+    ++ IVQL  Y NK  L   P W+  R D ++C+ ELKLG +A +CL PG +TL+ NL      K    L  W   Y  G  + +Y    S  FHG++  E   + +   ++ L+A++  + +  ++   + INP   +I I+  +     +A     + +  +YC  C    +S                  I  C  +   N+ +   E N   + + +  + R  +   +   +S+ ++           S    D TG F+W     FE   L + +   S   S+HI+VC+    +   I L +F+MPLR  N   +ELR I+ +G + Y   + W ++ NFP   +++GSP+    LR   +  C   VI++ N          +DK AI+C+  I++M         + L+++              IP++ E+  D    +       N D+++ +  ++PFA G  F  S + S + T Y N +  + I+T++ G  + E+E +        G  L P+  ++ +R      ++   +   P +E+   +     Y  LF     E  ILC GLYRL            +  +NR+V T+P   T + + D V+C
Sbjct:  129 IISGQNGTGRVL--ISIVSAL-SLGSLIIY-FIEISQLQGVTDELCIKWSESYTQQFDLAFNIVFLIFFCLRWIAATDKFWFWIEIYSLVDVLTVPPAFMTFVLNRYWVGLRFTRALRLISFTDVL-VFLNILKSSSKIRLCHLVTLFTSLVLTSAGFIHLIELTGDIPE-QTNKQNKTYFDYTYFMIATMSTVGYGDIVCKTWQGKLMMIFFILGGLAIFANSIPEIIEIIGNRNRYGGIFKKEIGKQHIILCGHI----------TFQRTNCDSGHPSTE-------------------------YSIAKCVEKKFKPARVQLEYADACLILCDKYSMDPDAEDAANIMRVISIKNYCPTIKVIVQLMQYHNKAYLMNIPSWDWRRGDDVVCVAELKLGFIAQSCLAPGFSTLLANLFVMRSFKKYHHLPEWVNQYVEGASLEMYTEYLSPSFHGLTFTEAVCVCFTKLNLLLIAVEVKSNNRRNHSSSIAINPK-PDITIEPGTQ-GFFIAESADDAKRAFYYCMACHMSCKSVKPCNCQSSQHFQDTLYNIVSCSWQMFNNNGKSLIERNSFSKPETVIRNRRKRFGGQSAKRRSQALNDTIHHIKFNEQSQRRFDSTGMFHWCSNREFESAILTNKDDLSSTVFSNHIVVCIFADANSPLIGLRSFVMPLRSSNYHYNELRQIIFVGPQDYLRRE-WKSLMNFPKIFVLNGSPLNRSKLRMININLCEMTVILSTNHSNGLVDAYLADKEAILCSLNIKAMKFTDDNLQSKDLSEIFKNLSTSASHQNSIIPMITELSVDSSVQYLDQDDEDNPDTELFL--TQPFACGRAFAVSVLDSLMSTAYFNENALTLIRTMVTGGATLELEELLSEGSGIQGAYLTPETVANRDRCR----VETMRLENSPYSEL---FGNEKTYGSLFMKCFKEYGILCFGLYRLIIDNMEDCSYSISTNKNRFVVTNPSPETPLMNQDWVFC 1060

[Close]

BLAST of Calcium-activated potassium channel subunit alpha-1 vs. Planmine SMEST
Match: SMESG000014623.1 (SMESG000014623.1)

HSP 1 Score: 266.159 bits (679), Expect = 2.528e-74
Identity = 208/793 (26.23%), Postives = 362/793 (45.65%), Query Frame = 2

Query:  467 EGANLQWIDFALNIFCLFHFTLRAFAANDILKFWIQPTTMIEITVIPNILLTSFLPVRRQGFSFLRIYYLRELCNTIAVSFGILKVNSKFEMTKVIFYIISLWLISAGLFHMFEGIGNFWEIPLFNQQ--LSFWRCCYFMLVTISTVGFGSVNPLTIFGRIVVLVYIIYGITMFVTVLPNVIRTI-QNLKYKNRYISKGNERHIIVCGKFESLTIIAFLKAFKRERFKGSVRNVKIVTMNKDLYDENLLMYMKRFSNPIKYLIGNLSNRKDLKRVNIQKAKLSVILSTPFTNKISEDDIDNIMTAMILKSQRKNMRTIVQLHLYSNKVLLKMSPMWNQNRSDIILCIDELKLGLMAYNCLTPGIATLVINLVTFTKSKSVSEL------WRKDYENGLKVLLYNVQFSDCFHGMSCLEVALIVYKLWDVCLLAIKCVNKSTDDYVLINPMIENIKIDTDSMIAIVMARDEASSNKLIFYCSKCSPQNQSEI-------CQCYLEATKNSPRGHYESNLQFENQRINE-SF---RSAYEFPTIDSKSEEIDINSYTGLDRTGSFYWAPEPNFEDVCLDIETAESRSLSDHILVCLCGIGHG-TIDLCNFMMPLRFQNLQNSELRTIVILGNKSYFEADKWTNIKNFPMFLIIDGSPIQSRDLRAAGLLKCHTCVIING-----NDKTVGFS--DKSAIICATLIRSM--RKLNKL------KIPIMIEIRKDEIAHHFSSIHSHNNDS-KVSVQHSEPFARGILFTNSTVYSCIYTVYKNPDTFSFIKTLLNGR 2734
            EGA L  ID     F   ++ +R  AA + ++FW    +++++  IP+  +  +L     G  FLR  +L ++ + +    G+LK  +KF + ++    I +W++ +G+ HM E  G+ W     N +  L+F    YF +VT+STVG+G ++P +  G+I V ++I+    +F + +P +   +    KY   Y+ K   +HI+VCG FE  +I +F+  F  E     +  + +V +N++  D  L   +K      K++ G + ++ DLKR +I +A    IL+        ++D  NIM  + LK+   ++R ++QL  Y NK  L   P WN+++ D ++C  E++L ++A +CL PG +T + NL +        E       W  DY NG+ + LY    S    GM+  ++ L  Y+  ++ L+A++ V       V INP  ++    T   +   +      S ++  YC+ C   N+          C C              + +   N++I + SF   R  +++  +D   +EID       D   S    P              E    S+HI++C+       +I L NF++PLR + L  ++LR I+I  N+ +   + W ++  FP    I  + I  + L    +  CH CVI++      N   + F   DK  I+    ++S+  +KL K       +IP    I K  + ++   +   + D     V  SE FA G  FT   +   +   Y NPD    I  L+ G 
Sbjct:  130 EGAFLLAIDLFCYSFFTCYYIIRFLAAENKIEFWFGVYSLVDLLTIPSFFVEIYLDHLWMGLRFLRAIWLMQVPDLLQY-LGVLKSATKFRLGQLSTMFICMWIVGSGMTHMLENTGDTWLSAEVNDKNFLTFGDSMYFTIVTMSTVGYGDISPHSFLGKIWVAIFILVSFAIFASFIPEIAEILFSGSKYTGSYVPKEEYKHIVVCGNFEFSSIQSFMADFFNE--DRPISKINVVFINQEEPDFELRNLLKMNFMRSKFIKGTVMDQVDLKRASIDEADACFILANHNCKNPKDEDAANIMRVISLKNFSSSVRVLIQLLQYENKSYLTNIPTWNKDKGDTVVCYSEMELRILAKSCLIPGYSTFISNLFSIRSEAQCKEFRKSGNSWINDYINGMGLELYTSNLSLSLIGMTFYDLVLFSYEYLNLLLIAVE-VKMRNGKTVFINPASQSYT--TKETVGYFICNSFKESQRVALYCNVCHGANEGTPLRVDKFKCVCI-------------NKVASLNEKIRQTSFRLSRQQFQYAILDKAEKEIDFLKCDYKDFKESLIKNP-------------LEPIKFSNHIILCIFADNDSPSIGLKNFIIPLRSKKLDTADLRPIIIASNEEFLHRE-WRSLACFPNLHPISFNNINKKSLSVLQVENCHVCVIMSARVSKRNAANLDFHLVDKEIILGTLNVKSIFKKKLQKKFIGKSGEIPNRFLITKLLVENNVQFLDQEDEDEPNCPVFLSEIFACGSAFTTKMLDCLLSIAYFNPDVNKVITHLIAGE 889

The following BLAST results are available for this feature:

BLAST of Calcium-activated potassium channel subunit alpha-1 vs. Ensembl Human
BLAST of Calcium-activated potassium channel subunit alpha-1 vs. Ensembl Celegans
BLAST of Calcium-activated potassium channel subunit alpha-1 vs. Ensembl Fly
BLAST of Calcium-activated potassium channel subunit alpha-1 vs. Ensembl Zebrafish
BLAST of Calcium-activated potassium channel subunit alpha-1 vs. Ensembl Xenopus
BLAST of Calcium-activated potassium channel subunit alpha-1 vs. Ensembl Mouse
BLAST of Calcium-activated potassium channel subunit alpha-1 vs. UniProt/SwissProt
BLAST of Calcium-activated potassium channel subunit alpha-1 vs. TrEMBL
BLAST of Calcium-activated potassium channel subunit alpha-1 vs. Ensembl Cavefish
BLAST of Calcium-activated potassium channel subunit alpha-1 vs. Ensembl Sea Lamprey
BLAST of Calcium-activated potassium channel subunit alpha-1 vs. Ensembl Yeast
BLAST of Calcium-activated potassium channel subunit alpha-1 vs. Ensembl Nematostella
BLAST of Calcium-activated potassium channel subunit alpha-1 vs. Ensembl Medaka
BLAST of Calcium-activated potassium channel subunit alpha-1 vs. Planmine SMEST

BLAST of Calcium-activated potassium channel subunit alpha-1 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
KCNMA1	5.504e-102	27.69	potassium calcium-activated channel subfamily M al...	[more]
KCNMA1	5.685e-102	28.19	potassium calcium-activated channel subfamily M al...	[more]
KCNMA1	5.703e-102	27.69	potassium calcium-activated channel subfamily M al...	[more]
KCNMA1	5.901e-102	27.72	potassium calcium-activated channel subfamily M al...	[more]
KCNMA1	6.343e-102	28.19	potassium calcium-activated channel subfamily M al...	[more]

BLAST of Calcium-activated potassium channel subunit alpha-1 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5


Match Name	E-value	Identity	Description
slo-1	7.204e-101	27.94	Calcium-activated potassium channel slo-1 [Source...	[more]
slo-1	8.084e-100	27.35	Calcium-activated potassium channel slo-1 [Source...	[more]
slo-1	8.780e-99	27.77	Calcium-activated potassium channel slo-1 [Source...	[more]
slo-1	4.846e-98	27.20	Calcium-activated potassium channel slo-1 [Source...	[more]
slo-1	6.085e-98	27.58	Calcium-activated potassium channel slo-1 [Source...	[more]

BLAST of Calcium-activated potassium channel subunit alpha-1 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5


Match Name	E-value	Identity	Description
slo	3.784e-101	27.24	gene:FBgn0003429 transcript:FBtr0334294	[more]
slo	2.051e-65	28.78	gene:FBgn0003429 transcript:FBtr0100636	[more]
slo	2.748e-65	28.78	gene:FBgn0003429 transcript:FBtr0084685	[more]
slo	2.935e-65	28.78	gene:FBgn0003429 transcript:FBtr0100627	[more]
slo	3.251e-65	29.23	gene:FBgn0003429 transcript:FBtr0330286	[more]

BLAST of Calcium-activated potassium channel subunit alpha-1 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
kcnma1a	2.585e-102	27.19	potassium large conductance calcium-activated chan...	[more]
kcnma1a	3.720e-100	27.11	potassium large conductance calcium-activated chan...	[more]
kcnma1a	1.103e-92	29.01	potassium large conductance calcium-activated chan...	[more]
CABZ01092907.1	1.538e-64	31.58	potassium large conductance calcium-activated chan...	[more]
kcnt1	1.023e-17	24.79	potassium channel, subfamily T, member 1 [Source:Z...	[more]

BLAST of Calcium-activated potassium channel subunit alpha-1 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5


Match Name	E-value	Identity	Description
KCNMA1	2.078e-100	27.46	potassium calcium-activated channel subfamily M al...	[more]
KCNMA1	2.373e-99	27.57	potassium calcium-activated channel subfamily M al...	[more]
KCNMA1	5.653e-98	27.28	potassium calcium-activated channel subfamily M al...	[more]
KCNMA1	4.879e-96	27.15	potassium calcium-activated channel subfamily M al...	[more]
KCNMA1	1.360e-95	26.80	potassium calcium-activated channel subfamily M al...	[more]

BLAST of Calcium-activated potassium channel subunit alpha-1 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Kcnma1	4.663e-103	27.93	potassium large conductance calcium-activated chan...	[more]
Kcnma1	5.442e-103	27.90	potassium large conductance calcium-activated chan...	[more]
Kcnma1	2.831e-102	27.90	potassium large conductance calcium-activated chan...	[more]
Kcnma1	3.232e-102	27.93	potassium large conductance calcium-activated chan...	[more]
Kcnma1	3.640e-102	28.19	potassium large conductance calcium-activated chan...	[more]

BLAST of Calcium-activated potassium channel subunit alpha-1 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|Q8AYS8\|KCMA1_CHICK	9.218e-107	28.43	Calcium-activated potassium channel subunit alpha-...	[more]
sp\|O18866\|KCMA1_PIG	6.362e-102	27.79	Calcium-activated potassium channel subunit alpha-...	[more]
sp\|O18867\|KCMA1_MACMU	9.253e-102	27.79	Calcium-activated potassium channel subunit alpha-...	[more]
sp\|Q9BG98\|KCMA1_RABIT	1.432e-101	27.79	Calcium-activated potassium channel subunit alpha-...	[more]
sp\|Q28204\|KCMA1_BOVIN	1.436e-101	27.79	Calcium-activated potassium channel subunit alpha-...	[more]

BLAST of Calcium-activated potassium channel subunit alpha-1 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
A0A5K4EWW8	2.010e-145	30.06	Uncharacterized protein OS=Schistosoma mansoni OX=...	[more]
A0A5K4EUY1	2.136e-145	30.06	Uncharacterized protein OS=Schistosoma mansoni OX=...	[more]
A0A5K4EUN8	3.506e-145	30.06	Uncharacterized protein OS=Schistosoma mansoni OX=...	[more]
A0A095ARG8	4.436e-145	30.16	Calcium-activated potassium channel subunit alpha-...	[more]
A0A4Z2CYR9	6.864e-142	29.76	Calcium-activated potassium channel subunit alpha-...	[more]

BLAST of Calcium-activated potassium channel subunit alpha-1 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ENSAMXT00000044980.1	3.074e-104	28.00	pep primary_assembly:Astyanax_mexicanus-2.0:APWO02...	[more]
ENSAMXT00000050440.1	6.546e-103	28.02	pep primary_assembly:Astyanax_mexicanus-2.0:APWO02...	[more]
ENSAMXT00000050702.1	1.245e-102	28.26	pep primary_assembly:Astyanax_mexicanus-2.0:APWO02...	[more]
ENSAMXT00000051878.1	8.795e-98	27.20	pep primary_assembly:Astyanax_mexicanus-2.0:APWO02...	[more]
ENSAMXT00000004500.2	1.845e-96	26.96	pep primary_assembly:Astyanax_mexicanus-2.0:APWO02...	[more]

BLAST of Calcium-activated potassium channel subunit alpha-1 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 4


Match Name	E-value	Identity	Description
ENSPMAT00000006399.1	7.534e-47	29.32	pep scaffold:Pmarinus_7.0:GL477091:41003:110164:-1...	[more]
ENSPMAT00000006404.1	9.581e-47	29.32	pep scaffold:Pmarinus_7.0:GL477091:42221:110230:-1...	[more]
ENSPMAT00000007042.1	8.740e-27	31.02	pep scaffold:Pmarinus_7.0:GL486096:7796:16492:-1 g...	[more]
KCNT1	6.646e-8	25.88	potassium sodium-activated channel subfamily T mem...	[more]

BLAST of Calcium-activated potassium channel subunit alpha-1 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of Calcium-activated potassium channel subunit alpha-1 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 2


Match Name	E-value	Identity	Description
EDO32743	1.633e-13	21.77	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO28098	1.019e-8	40.00	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of Calcium-activated potassium channel subunit alpha-1 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ENSORLT00000011055.2	3.496e-103	28.25	potassium calcium-activated channel subfamily M al...	[more]
kcnma1a	8.527e-103	27.32	calcium-activated potassium channel subunit alpha-...	[more]
kcnma1a	1.053e-98	26.65	calcium-activated potassium channel subunit alpha-...	[more]
kcnma1a	1.292e-98	26.79	calcium-activated potassium channel subunit alpha-...	[more]
kcnma1a	1.301e-92	26.61	calcium-activated potassium channel subunit alpha-...	[more]

BLAST of Calcium-activated potassium channel subunit alpha-1 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5


Match Name	E-value	Identity	Description
SMESG000040067.1	0.000e+0	99.21	SMESG000040067.1	[more]
SMESG000040071.1	0.000e+0	47.74	SMESG000040071.1	[more]
SMESG000050831.1	9.331e-92	28.41	SMESG000050831.1	[more]
SMESG000076792.1	1.060e-74	24.87	SMESG000076792.1	[more]
SMESG000014623.1	2.528e-74	26.23	SMESG000014623.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30028391 ID=SMED30028391|Name=Calcium-activated potassium channel subunit alpha-1|organism=Schmidtea mediterranea sexual|type=transcript|length=3119bp
TATATAAATCTTATATGTAGAAATTAAAATGAATTCATCCAAACAGTCAG
TTGGTTGCGATACCGATATTCTATGGTGGGTTTCATACAGCATTTCCGTT
GCAATATTTATTTGCGGATTCATGATTATTGGAATCAGTAACTGCGTTAA
TATTATCAGAGAAATTTTGGGAAAGAAAAAGAAAAAGATGGAAGCAATGA
AAAAAAGAAGAACTCGAATAACAATTTTTGAAAATAATTTTCCAACTAAT
AATAATTATAATTCGAATGTCAATAGTCTGTTTTCCATTTCTAGCAAATT
GAACTTTTTATCGTTCTGTGAAATCATGATTTCTAAAAGTACCATTGTTG
GGAGATTTCTGAATTTTGTCAAATTAATTTCCCAACTAACATCATGGGGA
ATTTTTGTTGTCTTTACTTTTAATCAGGTCAATGCAAATTATCTCATTGG
AGACTGTTTCGACGTCGAAGGTGCCAATTTACAATGGATTGATTTCGCTT
TGAACATATTTTGTCTTTTTCATTTTACGCTGAGAGCGTTTGCTGCAAAT
GATATTTTAAAATTCTGGATTCAGCCAACGACAATGATTGAAATCACTGT
CATTCCGAATATTCTCCTCACATCATTTCTTCCTGTTCGTCGCCAAGGAT
TCAGTTTTTTGAGAATTTACTATTTGCGGGAATTGTGCAACACCATAGCC
GTTTCATTCGGTATTTTAAAGGTCAATTCCAAATTTGAAATGACCAAAGT
TATATTTTACATAATTAGTTTATGGCTAATCAGCGCTGGCCTATTTCATA
TGTTTGAAGGAATTGGAAACTTTTGGGAAATTCCTCTTTTCAATCAACAG
CTATCATTTTGGAGATGCTGCTATTTTATGTTAGTCACGATTTCAACAGT
CGGATTTGGAAGTGTGAATCCCTTAACAATATTTGGACGAATAGTGGTTT
TAGTGTACATAATTTACGGAATAACAATGTTTGTCACAGTTTTACCAAAT
GTAATAAGGACCATTCAAAACCTGAAATATAAAAATAGATATATTTCAAA
AGGAAATGAAAGACACATAATTGTATGTGGGAAATTCGAAAGCCTGACCA
TTATTGCATTTCTAAAGGCATTTAAAAGGGAAAGATTTAAAGGATCTGTG
AGAAACGTTAAGATAGTCACAATGAACAAAGATTTATACGATGAAAACCT
TTTGATGTACATGAAGAGATTTTCAAATCCTATTAAATATTTGATTGGAA
ATCTTAGCAATCGAAAAGATCTAAAACGTGTTAATATTCAGAAAGCCAAA
TTGTCCGTTATTTTGAGTACGCCATTTACTAATAAAATAAGTGAGGACGA
CATTGACAACATTATGACAGCAATGATATTAAAATCCCAAAGGAAAAATA
TGCGAACTATTGTTCAACTGCATTTATATTCTAATAAGGTGCTTCTTAAA
ATGTCACCAATGTGGAATCAAAATCGGAGCGATATAATTCTATGTATAGA
TGAACTGAAACTTGGACTGATGGCGTACAATTGCTTGACCCCCGGCATAG
CCACTCTCGTCATAAACTTGGTGACATTTACAAAATCTAAGTCAGTTTCA
GAATTATGGAGAAAAGACTATGAAAACGGATTAAAGGTCTTGCTATATAA
TGTACAATTTTCCGACTGTTTTCATGGAATGTCTTGTTTAGAAGTAGCTT
TGATTGTTTATAAATTGTGGGATGTCTGTTTATTGGCAATAAAATGTGTC
AACAAATCTACAGATGATTACGTGTTGATCAACCCTATGATTGAAAACAT
CAAAATAGACACAGATTCGATGATAGCCATTGTTATGGCCAGGGATGAAG
CTTCTAGTAATAAGTTAATCTTTTATTGTTCAAAATGCAGCCCACAGAAT
CAATCAGAAATATGTCAATGTTATTTGGAAGCTACTAAAAATAGTCCGAG
GGGCCACTACGAGTCAAATTTGCAATTTGAAAATCAACGGATAAATGAAA
GTTTTCGGTCGGCTTATGAATTCCCAACAATTGATTCCAAATCTGAAGAA
ATAGACATAAACAGTTATACTGGACTGGATAGAACTGGATCATTCTATTG
GGCTCCTGAACCAAATTTTGAGGATGTCTGTCTGGATATTGAAACAGCAG
AAAGCCGAAGCCTTTCTGATCATATTCTTGTTTGTCTATGTGGCATCGGT
CATGGAACAATTGATTTATGCAATTTTATGATGCCTCTACGATTCCAAAA
TCTGCAAAATTCCGAGTTGCGGACAATAGTAATTTTGGGAAATAAAAGTT
ATTTCGAAGCTGATAAATGGACTAATATAAAAAATTTCCCAATGTTTTTA
ATTATCGACGGATCTCCGATTCAATCTCGAGACCTTCGAGCAGCAGGGCT
ACTGAAATGTCACACTTGCGTAATTATTAATGGAAATGACAAGACAGTTG
GATTTTCTGACAAGAGTGCCATTATATGTGCTACATTAATTAGATCAATG
AGGAAGCTCAATAAATTAAAAATACCAATAATGATTGAAATAAGAAAAGA
TGAAATTGCGCACCATTTCAGTTCGATTCACTCGCATAATAATGATAGCA
AAGTCTCGGTCCAGCACAGTGAGCCTTTTGCTAGAGGAATATTATTTACC
AATTCCACAGTATACAGCTGCATATATACAGTTTACAAAAATCCAGATAC
GTTTTCTTTTATCAAAACACTTCTCAACGGTCGTTATTCTGATGAGATTG
AATCTATGTTCGGATCAGGCGTTGGTTTGCTGCCTCAAAATTCATCTTCT
GAGAATCGGGAAAATTCTAATTCAATCATAAAGTTGTTTTCTGTTATACA
GCCTCCTTTAAACGAGATTTCGAGAGTATACGATGGTATATTGGATTATG
CCTGTCTATTTGAATGGGCACTAATGGAAAAGCGAATTCTTTGTTTGGGT
CTATATCGGCTAAATTTCGGCCGGAACCGTTACGTTTTCACTCACCCTGA
AAAGTCTACCGAAATATTTAGCACAGATCAAGTGTATTGTTGCGTGTCCA
GTGACTTCTTCAACACTCTCTGATGAAGCTTTTATATTATATATTTCATT
TCAATATTTTTTTTAAATA

protein sequence of SMED30028391-orf-1

>SMED30028391-orf-1 ID=SMED30028391-orf-1|Name=SMED30028391-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=1015bp
MNSSKQSVGCDTDILWWVSYSISVAIFICGFMIIGISNCVNIIREILGKK
KKKMEAMKKRRTRITIFENNFPTNNNYNSNVNSLFSISSKLNFLSFCEIM
ISKSTIVGRFLNFVKLISQLTSWGIFVVFTFNQVNANYLIGDCFDVEGAN
LQWIDFALNIFCLFHFTLRAFAANDILKFWIQPTTMIEITVIPNILLTSF
LPVRRQGFSFLRIYYLRELCNTIAVSFGILKVNSKFEMTKVIFYIISLWL
ISAGLFHMFEGIGNFWEIPLFNQQLSFWRCCYFMLVTISTVGFGSVNPLT
IFGRIVVLVYIIYGITMFVTVLPNVIRTIQNLKYKNRYISKGNERHIIVC
GKFESLTIIAFLKAFKRERFKGSVRNVKIVTMNKDLYDENLLMYMKRFSN
PIKYLIGNLSNRKDLKRVNIQKAKLSVILSTPFTNKISEDDIDNIMTAMI
LKSQRKNMRTIVQLHLYSNKVLLKMSPMWNQNRSDIILCIDELKLGLMAY
NCLTPGIATLVINLVTFTKSKSVSELWRKDYENGLKVLLYNVQFSDCFHG
MSCLEVALIVYKLWDVCLLAIKCVNKSTDDYVLINPMIENIKIDTDSMIA
IVMARDEASSNKLIFYCSKCSPQNQSEICQCYLEATKNSPRGHYESNLQF
ENQRINESFRSAYEFPTIDSKSEEIDINSYTGLDRTGSFYWAPEPNFEDV
CLDIETAESRSLSDHILVCLCGIGHGTIDLCNFMMPLRFQNLQNSELRTI
VILGNKSYFEADKWTNIKNFPMFLIIDGSPIQSRDLRAAGLLKCHTCVII
NGNDKTVGFSDKSAIICATLIRSMRKLNKLKIPIMIEIRKDEIAHHFSSI
HSHNNDSKVSVQHSEPFARGILFTNSTVYSCIYTVYKNPDTFSFIKTLLN
GRYSDEIESMFGSGVGLLPQNSSSENRENSNSIIKLFSVIQPPLNEISRV
YDGILDYACLFEWALMEKRILCLGLYRLNFGRNRYVFTHPEKSTEIFSTD
QVYCCVSSDFFNTL*

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000418	head
PLANA:0002111	X2 cell

Vocabulary: **INTERPRO**
Term	Definition
IPR036291	NAD(P)-bd_dom_sf
IPR003280	2pore_dom_K_chnl
IPR003929	K_chnl_BK_asu
IPR013099	K_chnl_dom
IPR016040	NAD(P)-bd_dom

Vocabulary: **molecular function**
Term	Definition
GO:0005267	potassium channel activity
GO:0015269	calcium-activated potassium channel activity
GO:0005216	ion channel activity
GO:0005244	voltage-gated ion channel activity
GO:0005249	voltage-gated potassium channel activity
GO:0005515	protein binding
GO:0046872	metal ion binding
GO:0060072	large conductance calcium-activated potassium channel activity

Vocabulary: **cellular component**
Term	Definition
GO:0016020	membrane
GO:0008076	voltage-gated potassium channel complex
GO:0016021	integral component of membrane

Vocabulary: **biological process**
Term	Definition
GO:0071805	potassium ion transmembrane transport
GO:0006813	potassium ion transport
GO:0006810	transport
GO:0006811	ion transport
GO:0034765	regulation of ion transmembrane transport
GO:0055085	transmembrane transport

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR003280	Two pore domain potassium channel	PRINTS	PR01333	2POREKCHANEL	coord: 290..318 score: 34.09 coord: 809..818 score: 41.22
IPR013099	Potassium channel domain	PFAM	PF07885	Ion_trans_2	coord: 249..333 e-value: 1.4E-12 score: 47.4
None	No IPR available	GENE3D	G3DSA:3.40.50.720		coord: 347..481 e-value: 1.4E-13 score: 52.9 coord: 712..858 e-value: 1.2E-8 score: 37.0
None	No IPR available	GENE3D	G3DSA:1.10.287.70		coord: 238..346 e-value: 1.1E-13 score: 52.8
None	No IPR available	PANTHER	PTHR10027:SF33	POTASSIUM LARGE CONDUCTANCE CALCIUM-ACTIVATED CHANNEL, SUBFAMILY M, ALPHA MEMBER 1A	coord: 127..1012
None	No IPR available	PANTHER	PTHR10027	CALCIUM-ACTIVATED POTASSIUM CHANNEL ALPHA CHAIN	coord: 127..1012
None	No IPR available	SUPERFAMILY	SSF81324	Voltage-gated potassium channels	coord: 215..356
None	No IPR available	TMHMM	TMhelix		coord: 245..264
None	No IPR available	TMHMM	TMhelix		coord: 25..47
None	No IPR available	TMHMM	TMhelix		coord: 279..301
None	No IPR available	TMHMM	TMhelix		coord: 155..177
None	No IPR available	TMHMM	TMhelix		coord: 113..135
None	No IPR available	TMHMM	TMhelix		coord: 308..330
IPR003929	Calcium-activated potassium channel BK, alpha subunit	PFAM	PF03493	BK_channel_a	coord: 482..575 e-value: 1.8E-21 score: 76.1
IPR036291	NAD(P)-binding domain superfamily	SUPERFAMILY	SSF51735	NAD(P)-binding Rossmann-fold domains	coord: 349..512

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Calcium-activated potassium channel subunit alpha-1

Zeng et. al., 2018

▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Davies et. al., 2017

PAGE et. al., 2020

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 3

Owlery

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