Ras-related protein

Overview
NameRas-related protein
Smed IDSMED30028380
Length (bp)741
Neoblast Clusters

Zeng et. al., 2018




▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 



 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)




Explore this single cell expression dataset with our NB Cluster Shiny App




 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Ras-related protein (SMED30028380) t-SNE clustered cells

Violin plots show distribution of expression levels for Ras-related protein (SMED30028380) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Ras-related protein (SMED30028380) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Ras-related protein (SMED30028380) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017




Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020




SMED30028380

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 13

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
gutSMED30028380h1SMcG0005592 Contig3946newmark_estsPMID:23079596
Forsthoefel et al., 2012
whole organism asexual adult colorimetric in situ hybridization evidence
gutSMED30028380h1SMcG0005592 Contig3946uc_Smed_v2PMID:23079596
Forsthoefel et al., 2012
whole organism asexual adult colorimetric in situ hybridization evidence
dorsal ventral margin of the whole animalSMED30028380h1SMcG0005592 Contig3946newmark_estsPMID:23079596
Forsthoefel et al., 2012
whole organism asexual adult colorimetric in situ hybridization evidence
dorsal ventral margin of the whole animalSMED30028380h1SMcG0005592 Contig3946uc_Smed_v2PMID:23079596
Forsthoefel et al., 2012
whole organism asexual adult colorimetric in situ hybridization evidence
intestinal phagocyteSMED30028380h1SMcG0005592 Contig3946newmark_estsPMID:23079596
Forsthoefel et al., 2012
FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
intestinal phagocyteSMED30028380h1SMcG0005592 Contig3946uc_Smed_v2PMID:23079596
Forsthoefel et al., 2012
FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
gutSMED30028380h1SMcG0017984 Contig3946newmark_estsPMID:23079596
Forsthoefel et al., 2012
whole organism asexual adult colorimetric in situ hybridization evidence
gutSMED30028380h1SMcG0017984 Contig3946uc_Smed_v2PMID:23079596
Forsthoefel et al., 2012
whole organism asexual adult colorimetric in situ hybridization evidence
dorsal ventral margin of the whole animalSMED30028380h1SMcG0017984 Contig3946newmark_estsPMID:23079596
Forsthoefel et al., 2012
whole organism asexual adult colorimetric in situ hybridization evidence
dorsal ventral margin of the whole animalSMED30028380h1SMcG0017984 Contig3946uc_Smed_v2PMID:23079596
Forsthoefel et al., 2012
whole organism asexual adult colorimetric in situ hybridization evidence
intestinal phagocyteSMED30028380h1SMcG0017984 Contig3946newmark_estsPMID:23079596
Forsthoefel et al., 2012
FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
intestinal phagocyteSMED30028380h1SMcG0017984 Contig3946uc_Smed_v2PMID:23079596
Forsthoefel et al., 2012
FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
epidermisSMED30028380h1SMcG0005592 dd_Smed_v4_4604_0_1dd_Smed_v4PMID:28292427
Wurtzel et al., 2017
whole organism asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
BLAST of Ras-related protein vs. Ensembl Human
Match: MRAS (muscle RAS oncogene homolog [Source:HGNC Symbol;Acc:HGNC:7227])

HSP 1 Score: 181.415 bits (459), Expect = 9.350e-57
Identity = 100/178 (56.18%), Postives = 133/178 (74.72%), Query Frame = 3
Query:   45 LPSDLSNMSKMKXXXXXXXXXXKSAIILQFMQKIFVENHDPTIESTYYKNYEVDGEWSNLEVQDTAGQEEFASMRESYYRAANGFLIVFSLTTRESFEIVRRFFQSALRSRDRDHFPMLLVANKTDLEMNRKVTTSEIESLAKELQIDYIETSAKNPPINIEDAFSQIVRKIRSHQQI 578
            +PSD  N+   K+VV+GDGGVGKSA+ +QF QKIFV ++DPTIE +Y K+ E+D +W+ L+V DTAGQEEF++MRE Y R  +GFLIV+S+T + SFE V RF Q  LR +DR+ FPM+LVANK DL   RK+T  + + +A +  I YIETSAK+PP+N++ AF  +VR IR  QQI
Sbjct:    6 VPSD--NLPTYKLVVVGDGGVGKSALTIQFFQKIFVPDYDPTIEDSYLKHTEIDNQWAILDVLDTAGQEEFSAMREQYMRTGDGFLIVYSVTDKASFEHVDRFHQLILRVKDRESFPMILVANKVDLMHLRKITREQGKEMATKHNIPYIETSAKDPPLNVDKAFHDLVRVIR--QQI 179          
BLAST of Ras-related protein vs. Ensembl Human
Match: MRAS (muscle RAS oncogene homolog [Source:HGNC Symbol;Acc:HGNC:7227])

HSP 1 Score: 181.415 bits (459), Expect = 9.350e-57
Identity = 100/178 (56.18%), Postives = 133/178 (74.72%), Query Frame = 3
Query:   45 LPSDLSNMSKMKXXXXXXXXXXKSAIILQFMQKIFVENHDPTIESTYYKNYEVDGEWSNLEVQDTAGQEEFASMRESYYRAANGFLIVFSLTTRESFEIVRRFFQSALRSRDRDHFPMLLVANKTDLEMNRKVTTSEIESLAKELQIDYIETSAKNPPINIEDAFSQIVRKIRSHQQI 578
            +PSD  N+   K+VV+GDGGVGKSA+ +QF QKIFV ++DPTIE +Y K+ E+D +W+ L+V DTAGQEEF++MRE Y R  +GFLIV+S+T + SFE V RF Q  LR +DR+ FPM+LVANK DL   RK+T  + + +A +  I YIETSAK+PP+N++ AF  +VR IR  QQI
Sbjct:    6 VPSD--NLPTYKLVVVGDGGVGKSALTIQFFQKIFVPDYDPTIEDSYLKHTEIDNQWAILDVLDTAGQEEFSAMREQYMRTGDGFLIVYSVTDKASFEHVDRFHQLILRVKDRESFPMILVANKVDLMHLRKITREQGKEMATKHNIPYIETSAKDPPLNVDKAFHDLVRVIR--QQI 179          
BLAST of Ras-related protein vs. Ensembl Human
Match: MRAS (muscle RAS oncogene homolog [Source:HGNC Symbol;Acc:HGNC:7227])

HSP 1 Score: 181.415 bits (459), Expect = 9.350e-57
Identity = 100/178 (56.18%), Postives = 133/178 (74.72%), Query Frame = 3
Query:   45 LPSDLSNMSKMKXXXXXXXXXXKSAIILQFMQKIFVENHDPTIESTYYKNYEVDGEWSNLEVQDTAGQEEFASMRESYYRAANGFLIVFSLTTRESFEIVRRFFQSALRSRDRDHFPMLLVANKTDLEMNRKVTTSEIESLAKELQIDYIETSAKNPPINIEDAFSQIVRKIRSHQQI 578
            +PSD  N+   K+VV+GDGGVGKSA+ +QF QKIFV ++DPTIE +Y K+ E+D +W+ L+V DTAGQEEF++MRE Y R  +GFLIV+S+T + SFE V RF Q  LR +DR+ FPM+LVANK DL   RK+T  + + +A +  I YIETSAK+PP+N++ AF  +VR IR  QQI
Sbjct:    6 VPSD--NLPTYKLVVVGDGGVGKSALTIQFFQKIFVPDYDPTIEDSYLKHTEIDNQWAILDVLDTAGQEEFSAMREQYMRTGDGFLIVYSVTDKASFEHVDRFHQLILRVKDRESFPMILVANKVDLMHLRKITREQGKEMATKHNIPYIETSAKDPPLNVDKAFHDLVRVIR--QQI 179          
BLAST of Ras-related protein vs. Ensembl Human
Match: RRAS2 (RAS related 2 [Source:HGNC Symbol;Acc:HGNC:17271])

HSP 1 Score: 159.073 bits (401), Expect = 4.545e-48
Identity = 91/206 (44.17%), Postives = 131/206 (63.59%), Query Frame = 3
Query:   54 DLSNMSKMKXXXXXXXXXXKSAIILQFMQKIFVENHDPTIESTYYKNYEVDGEWSNLEVQDTAGQEEFASMRESYYRAANGFLIVFSLTTRESFEIVRRFFQSALRSRDRDHFPMLLVANKTDLEMNRKVTTSEIESLAKELQIDYIETSAKNPPINIEDAFSQIVRKIRSHQQINDVKLKSRPRQKQKCCLM*KTANNNWTLCHC 671
            D S   K ++VV+G GGVGKSA+ +QF+Q  FV ++DPTIE +Y K   +D   + L++ DTAGQEEF +MRE Y R   GFL+VFS+T R SFE + +F +  LR +DRD FPM+L+ NK DL+  R+VT  E + LA++L++ Y+E SAK   +N++ AF ++VR IR  Q+  +      P +K+K          +   CHC
Sbjct:    8 DGSGQEKYRLVVVGGGGVGKSALTIQFIQSYFVTDYDPTIEDSYTKQCVIDDRAARLDILDTAGQEEFGAMREQYMRTGEGFLLVFSVTDRGSFEEIYKFQRQILRVKDRDEFPMILIGNKADLDHQRQVTQEEGQQLARQLKVTYMEASAK-IRMNVDQAFHELVRVIRKFQE-QECPPSPEPTRKEK----------DKKGCHC 201          
BLAST of Ras-related protein vs. Ensembl Human
Match: RRAS (RAS related [Source:HGNC Symbol;Acc:HGNC:10447])

HSP 1 Score: 157.532 bits (397), Expect = 2.986e-47
Identity = 80/173 (46.24%), Postives = 110/173 (63.58%), Query Frame = 3
Query:  111 KSAIILQFMQKIFVENHDPTIESTYYKNYEVDGEWSNLEVQDTAGQEEFASMRESYYRAANGFLIVFSLTTRESFEIVRRFFQSALRSRDRDHFPMLLVANKTDLEMNRKVTTSEIESLAKELQIDYIETSAKNPPINIEDAFSQIVRKIRSHQ-QINDVKLKSRPRQKQKCC 626
            KSA+ +QF+Q  FV ++DPTIE +Y K   VDG  + L++ DTAGQEEF +MRE Y RA +GFL+VF++  R+SF  V + F   LR +DRD FP++LV NK DLE  R+V  SE  +      + Y E SAK   +N+++AF Q+VR +R +Q Q       S PR+K   C
Sbjct:   42 KSALTIQFIQSYFVSDYDPTIEDSYTKICSVDGIPARLDILDTAGQEEFGAMREQYMRAGHGFLLVFAINDRQSFNEVGKLFTQILRVKDRDDFPVVLVGNKADLESQRQVPRSEASAFGASHHVAYFEASAKL-RLNVDEAFEQLVRAVRKYQEQELPPSPPSAPRKKGGGC 213          
BLAST of Ras-related protein vs. Ensembl Celegans
Match: ras-2 (GTP binding protein; R-RAS related [Source:UniProtKB/TrEMBL;Acc:G5EGA7])

HSP 1 Score: 172.94 bits (437), Expect = 8.314e-54
Identity = 95/194 (48.97%), Postives = 133/194 (68.56%), Query Frame = 3
Query:   48 PSDLSNMSKMKXXXXXXXXXXKSAIILQFMQKIFVENHDPTIESTYYKNYEVDGEWSNLEVQDTAGQEEFASMRESYYRAANGFLIVFSLTTRESFEIVRRFFQSALRSRDRDHFPMLLVANKTDLEMNRKVTTSEIESLAKELQIDYIETSAKNPPINIEDAFSQIVRKIR---SHQQINDVKLKSRPRQKQK 620
            P D S +   K+VVIGDGGVGKS++ +QF QK FV+ +DPTIE  Y ++ E+DG W  ++V DTAGQEEF++MRE Y R   GFL+VFS+T R+SFE   + +   LR +DR  +P+LLVANK DL   R V+  E   LA +L++ YIETSAK PP+N++ AF ++VR +R   S +  ++  + S PR K++
Sbjct:    9 PEDDSKLPYYKLVVIGDGGVGKSSLTIQFFQKQFVDYYDPTIEDQYIQHCEIDGNWVIMDVLDTAGQEEFSAMREQYIRGGRGFLLVFSVTERKSFEEAHKLYNQVLRVKDRSEYPVLLVANKVDLINQRVVSEQEGRELAAQLKLMYIETSAKEPPVNVDAAFHELVRIVRSFPSDEGDHEASMASVPRTKKR 202          
BLAST of Ras-related protein vs. Ensembl Celegans
Match: ras-2 (GTP binding protein; R-RAS related [Source:UniProtKB/TrEMBL;Acc:G5EGA7])

HSP 1 Score: 172.94 bits (437), Expect = 8.314e-54
Identity = 95/194 (48.97%), Postives = 133/194 (68.56%), Query Frame = 3
Query:   48 PSDLSNMSKMKXXXXXXXXXXKSAIILQFMQKIFVENHDPTIESTYYKNYEVDGEWSNLEVQDTAGQEEFASMRESYYRAANGFLIVFSLTTRESFEIVRRFFQSALRSRDRDHFPMLLVANKTDLEMNRKVTTSEIESLAKELQIDYIETSAKNPPINIEDAFSQIVRKIR---SHQQINDVKLKSRPRQKQK 620
            P D S +   K+VVIGDGGVGKS++ +QF QK FV+ +DPTIE  Y ++ E+DG W  ++V DTAGQEEF++MRE Y R   GFL+VFS+T R+SFE   + +   LR +DR  +P+LLVANK DL   R V+  E   LA +L++ YIETSAK PP+N++ AF ++VR +R   S +  ++  + S PR K++
Sbjct:    9 PEDDSKLPYYKLVVIGDGGVGKSSLTIQFFQKQFVDYYDPTIEDQYIQHCEIDGNWVIMDVLDTAGQEEFSAMREQYIRGGRGFLLVFSVTERKSFEEAHKLYNQVLRVKDRSEYPVLLVANKVDLINQRVVSEQEGRELAAQLKLMYIETSAKEPPVNVDAAFHELVRIVRSFPSDEGDHEASMASVPRTKKR 202          
BLAST of Ras-related protein vs. Ensembl Celegans
Match: ras-1 (GTP binding protein; R-RAS related; R-ras1 homolog [Source:UniProtKB/TrEMBL;Acc:G5EBK8])

HSP 1 Score: 156.762 bits (395), Expect = 1.573e-47
Identity = 81/170 (47.65%), Postives = 112/170 (65.88%), Query Frame = 3
Query:  111 KSAIILQFMQKIFVENHDPTIESTYYKNYEVDGEWSNLEVQDTAGQEEFASMRESYYRAANGFLIVFSLTTRESFEIVRRFFQSALRSRDRDHFPMLLVANKTDLEMNRKVTTSEIESLAKELQIDYIETSAKNPPINIEDAFSQIVRKIRSHQQINDVKLKSRPRQKQK 620
            KSA+ +QF+Q+ FV+++DPTIE +Y K   VD +   LE+ DTAGQEEF++MRE Y R  +GFLIVF++T R SFE V++  +   R +DRD FP++LV NK DLE  R V   E E LA  L I Y+E SAK    N+++AF  IVR +R +Q  +D ++   P   +K
Sbjct:   30 KSALTIQFIQRYFVQDYDPTIEDSYTKQCFVDEDLCKLEILDTAGQEEFSTMREQYLRTGSGFLIVFAVTDRNSFEEVKKLHELICRIKDRDDFPIILVGNKADLENERHVARHEAEELAHRLSIPYLECSAKIRK-NVDEAFFDIVRLVRKYQ--HDERMPIHPHDDRK 196          
BLAST of Ras-related protein vs. Ensembl Celegans
Match: let-60 (Ras protein let-60 [Source:UniProtKB/Swiss-Prot;Acc:P22981])

HSP 1 Score: 137.117 bits (344), Expect = 3.062e-40
Identity = 72/174 (41.38%), Postives = 111/174 (63.79%), Query Frame = 3
Query:  111 KSAIILQFMQKIFVENHDPTIESTYYKNYEVDGEWSNLEVQDTAGQEEFASMRESYYRAANGFLIVFSLTTRESFEIVRRFFQSALRSRDRDHFPMLLVANKTDLEMNRKVTTSEIESLAKELQIDYIETSAKNPPINIEDAFSQIVRKIRSHQQINDVKLKSRPRQKQKCCLM 632
            KSA+ +Q +Q  FVE +DPTIE +Y K   +DGE   L++ DTAGQEE+++MR+ Y R   GFL+VF++   +SFE V  + +   R +D D  PM+LV NK DL  +R V    +   AK   I  ++TSAK   + +++AF  +VR+IR H++ +D    ++P++K+KC +M
Sbjct:   16 KSALTIQLIQNHFVEEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLLVFAVNEAKSFENVANYREQIRRVKDSDDVPMVLVGNKCDLS-SRSVDFRTVSETAKGYGIPNVDTSAKT-RMGVDEAFYTLVREIRKHRERHD---NNKPQKKKKCQIM 184          
BLAST of Ras-related protein vs. Ensembl Celegans
Match: rap-1 (Ras-related protein Rap-1 [Source:UniProtKB/Swiss-Prot;Acc:Q18246])

HSP 1 Score: 136.346 bits (342), Expect = 7.880e-40
Identity = 74/175 (42.29%), Postives = 106/175 (60.57%), Query Frame = 3
Query:  111 KSAIILQFMQKIFVENHDPTIESTYYKNYEVDGEWSNLEVQDTAGQEEFASMRESYYRAANGFLIVFSLTTRESFEIVRRFFQSALRSRDRDHFPMLLVANKTDLEMNRKVTTSEIESLAKELQIDYIETSAKNPPINIEDAFSQIVRKIRSHQQINDVKLKSRPRQKQ---KCC 626
            KSA+ +QF+Q IFVE +DPTIE +Y K  EVDG+   LE+ DTAG E+F +MR+ Y +   GF++V+S+T + +F  +       LR +D D  PM+LV NK DLE  R V   + ++LA++    ++ETSAK   IN+ + F  +VR      QIN    +S  RQ Q   +CC
Sbjct:   16 KSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDGQQCMLEILDTAGTEQFTAMRDLYMKNGQGFVLVYSITAQSTFNDLMDLRDQILRVKDTDEVPMILVGNKCDLEDERVVGKDQGQNLARQFGSAFLETSAK-AKINVSEVFYDLVR------QINRRYPESGRRQGQSNKQCC 183          
BLAST of Ras-related protein vs. Ensembl Fly
Match: Ras64B (gene:FBgn0003206 transcript:FBtr0073212)

HSP 1 Score: 153.68 bits (387), Expect = 2.095e-46
Identity = 79/182 (43.41%), Postives = 116/182 (63.74%), Query Frame = 3
Query:  111 KSAIILQFMQKIFVENHDPTIESTYYKNYEVDGEWSNLEVQDTAGQEEFASMRESYYRAANGFLIVFSLTTRESFEIVRRFFQSALRSRDRDHFPMLLVANKTDLEMNRKVTTSEIESLAKELQIDYIETSAKNPPINIEDAFSQIVRKIRSHQQINDVKLKSRP--------RQKQKCCLM 632
            KSAI +QF+Q  FV ++DPTIE +Y K   +D   + L++ DTAGQEEF++MRE Y R+  GFL+VF+L    SF+ + +F +  LR +DRD FPML+V NK DL+  ++V+  E ++ ++ L I YIE SAK   +N++ AF ++VR +R  Q      +  RP        + K+KCCLM
Sbjct:   18 KSAITIQFIQSYFVTDYDPTIEDSYTKQCNIDDVPAKLDILDTAGQEEFSAMREQYMRSGEGFLLVFALNDHSSFDEIPKFQRQILRVKDRDEFPMLMVGNKCDLKHQQQVSLEEAQNTSRNLMIPYIECSAK-LRVNVDQAFHELVRIVRKFQ------IAERPFIEQDYKKKGKRKCCLM 192          
BLAST of Ras-related protein vs. Ensembl Fly
Match: Rala (gene:FBgn0015286 transcript:FBtr0070582)

HSP 1 Score: 138.272 bits (347), Expect = 2.282e-40
Identity = 69/174 (39.66%), Postives = 107/174 (61.49%), Query Frame = 3
Query:  111 KSAIILQFMQKIFVENHDPTIESTYYKNYEVDGEWSNLEVQDTAGQEEFASMRESYYRAANGFLIVFSLTTRESFEIVRRFFQSALRSRDRDHFPMLLVANKTDLEMNRKVTTSEIESLAKELQIDYIETSAKNPPINIEDAFSQIVRKIRSHQQINDVKLKSRPRQKQKCCLM 632
            KSA+ LQFM   FVE+++PT   +Y K   +DGE   +++ DTAGQE++A++R++Y+R+  GFL VFS+T  ESF+  + F +  LR ++ +  P LLV NK DL   RKV  SE +  A++  + Y+ETSAK    N++  F  ++R I S ++     +K  P+    CC +
Sbjct:   24 KSALTLQFMYDEFVEDYEPTKADSYRKKVVLDGEEVQIDILDTAGQEDYAAIRDNYFRSGEGFLCVFSITDDESFQATQEFREQILRVKNDESIPFLLVGNKCDLNDKRKVPLSECQLRAQQWAVPYVETSAKTRE-NVDKVFYDLIRDISSRKKQRQTDVKQPPKPNSHCCQL 196          
BLAST of Ras-related protein vs. Ensembl Fly
Match: Rap1 (gene:FBgn0004636 transcript:FBtr0303154)

HSP 1 Score: 135.191 bits (339), Expect = 2.704e-39
Identity = 66/150 (44.00%), Postives = 97/150 (64.67%), Query Frame = 3
Query:  111 KSAIILQFMQKIFVENHDPTIESTYYKNYEVDGEWSNLEVQDTAGQEEFASMRESYYRAANGFLIVFSLTTRESFEIVRRFFQSALRSRDRDHFPMLLVANKTDLEMNRKVTTSEIESLAKELQIDYIETSAKNPPINIEDAFSQIVRKI 560
            KSA+ +QF+Q IFVE +DPTIE +Y K  EVDG+   LE+ DTAG E+F +MR+ Y +   GF++V+S+T + +F  ++   +  LR +D D  PM+LV NK DLE  R V     ++LA +    ++ETSAK   +N+ D F  +VR+I
Sbjct:   16 KSALTVQFVQCIFVEKYDPTIEDSYRKQVEVDGQQCMLEILDTAGTEQFTAMRDLYMKNGQGFVLVYSITAQSTFNDLQDLREQILRVKDTDDVPMVLVGNKCDLEEERVVGKELGKNLATQFNCAFMETSAK-AKVNVNDIFYDLVRQI 164          
BLAST of Ras-related protein vs. Ensembl Fly
Match: Rap1 (gene:FBgn0004636 transcript:FBtr0072867)

HSP 1 Score: 135.191 bits (339), Expect = 2.704e-39
Identity = 66/150 (44.00%), Postives = 97/150 (64.67%), Query Frame = 3
Query:  111 KSAIILQFMQKIFVENHDPTIESTYYKNYEVDGEWSNLEVQDTAGQEEFASMRESYYRAANGFLIVFSLTTRESFEIVRRFFQSALRSRDRDHFPMLLVANKTDLEMNRKVTTSEIESLAKELQIDYIETSAKNPPINIEDAFSQIVRKI 560
            KSA+ +QF+Q IFVE +DPTIE +Y K  EVDG+   LE+ DTAG E+F +MR+ Y +   GF++V+S+T + +F  ++   +  LR +D D  PM+LV NK DLE  R V     ++LA +    ++ETSAK   +N+ D F  +VR+I
Sbjct:   16 KSALTVQFVQCIFVEKYDPTIEDSYRKQVEVDGQQCMLEILDTAGTEQFTAMRDLYMKNGQGFVLVYSITAQSTFNDLQDLREQILRVKDTDDVPMVLVGNKCDLEEERVVGKELGKNLATQFNCAFMETSAK-AKVNVNDIFYDLVRQI 164          
BLAST of Ras-related protein vs. Ensembl Fly
Match: Rap1 (gene:FBgn0004636 transcript:FBtr0332671)

HSP 1 Score: 135.191 bits (339), Expect = 2.704e-39
Identity = 66/150 (44.00%), Postives = 97/150 (64.67%), Query Frame = 3
Query:  111 KSAIILQFMQKIFVENHDPTIESTYYKNYEVDGEWSNLEVQDTAGQEEFASMRESYYRAANGFLIVFSLTTRESFEIVRRFFQSALRSRDRDHFPMLLVANKTDLEMNRKVTTSEIESLAKELQIDYIETSAKNPPINIEDAFSQIVRKI 560
            KSA+ +QF+Q IFVE +DPTIE +Y K  EVDG+   LE+ DTAG E+F +MR+ Y +   GF++V+S+T + +F  ++   +  LR +D D  PM+LV NK DLE  R V     ++LA +    ++ETSAK   +N+ D F  +VR+I
Sbjct:   16 KSALTVQFVQCIFVEKYDPTIEDSYRKQVEVDGQQCMLEILDTAGTEQFTAMRDLYMKNGQGFVLVYSITAQSTFNDLQDLREQILRVKDTDDVPMVLVGNKCDLEEERVVGKELGKNLATQFNCAFMETSAK-AKVNVNDIFYDLVRQI 164          
BLAST of Ras-related protein vs. Ensembl Zebrafish
Match: si:ch73-116o1.2 (si:ch73-116o1.2 [Source:ZFIN;Acc:ZDB-GENE-110411-67])

HSP 1 Score: 185.652 bits (470), Expect = 1.546e-58
Identity = 102/178 (57.30%), Postives = 133/178 (74.72%), Query Frame = 3
Query:   45 LPSDLSNMSKMKXXXXXXXXXXKSAIILQFMQKIFVENHDPTIESTYYKNYEVDGEWSNLEVQDTAGQEEFASMRESYYRAANGFLIVFSLTTRESFEIVRRFFQSALRSRDRDHFPMLLVANKTDLEMNRKVTTSEIESLAKELQIDYIETSAKNPPINIEDAFSQIVRKIRSHQQI 578
            +P D  N+   K+VV+GDGGVGKSA+ +QF QKIFV ++DPTIE +Y K+ E+DG+W+ L+V DTAGQEEF++MRE Y R  +GFLIVFS+T + SFE V RF Q  LR +DR+ FPM+LVANK DL   RKVT  +   +A +  I YIETSAK+PP+N+E AF ++VR IR  QQ+
Sbjct:    6 VPGD--NLPTYKLVVVGDGGVGKSALTIQFFQKIFVPDYDPTIEDSYLKHTEIDGQWAILDVLDTAGQEEFSAMREQYMRTGDGFLIVFSVTDKASFEHVDRFHQLILRVKDRESFPMVLVANKVDLVHLRKVTNEQGCEMAAKHNITYIETSAKDPPMNVERAFHELVRVIR--QQV 179          
BLAST of Ras-related protein vs. Ensembl Zebrafish
Match: MRAS (si:ch73-116o1.2 [Source:ZFIN;Acc:ZDB-GENE-110411-67])

HSP 1 Score: 185.652 bits (470), Expect = 1.546e-58
Identity = 102/178 (57.30%), Postives = 133/178 (74.72%), Query Frame = 3
Query:   45 LPSDLSNMSKMKXXXXXXXXXXKSAIILQFMQKIFVENHDPTIESTYYKNYEVDGEWSNLEVQDTAGQEEFASMRESYYRAANGFLIVFSLTTRESFEIVRRFFQSALRSRDRDHFPMLLVANKTDLEMNRKVTTSEIESLAKELQIDYIETSAKNPPINIEDAFSQIVRKIRSHQQI 578
            +P D  N+   K+VV+GDGGVGKSA+ +QF QKIFV ++DPTIE +Y K+ E+DG+W+ L+V DTAGQEEF++MRE Y R  +GFLIVFS+T + SFE V RF Q  LR +DR+ FPM+LVANK DL   RKVT  +   +A +  I YIETSAK+PP+N+E AF ++VR IR  QQ+
Sbjct:    6 VPGD--NLPTYKLVVVGDGGVGKSALTIQFFQKIFVPDYDPTIEDSYLKHTEIDGQWAILDVLDTAGQEEFSAMREQYMRTGDGFLIVFSVTDKASFEHVDRFHQLILRVKDRESFPMVLVANKVDLVHLRKVTNEQGCEMAAKHNITYIETSAKDPPMNVERAFHELVRVIR--QQV 179          
BLAST of Ras-related protein vs. Ensembl Zebrafish
Match: mras (muscle RAS oncogene homolog [Source:ZFIN;Acc:ZDB-GENE-050208-495])

HSP 1 Score: 185.267 bits (469), Expect = 1.797e-58
Identity = 101/178 (56.74%), Postives = 134/178 (75.28%), Query Frame = 3
Query:   45 LPSDLSNMSKMKXXXXXXXXXXKSAIILQFMQKIFVENHDPTIESTYYKNYEVDGEWSNLEVQDTAGQEEFASMRESYYRAANGFLIVFSLTTRESFEIVRRFFQSALRSRDRDHFPMLLVANKTDLEMNRKVTTSEIESLAKELQIDYIETSAKNPPINIEDAFSQIVRKIRSHQQI 578
            +P D  N+   K+VV+GDGGVGKSA+ +QF QKIFV ++DPTIE +Y K+ E+DG+W+ L+V DTAGQEEF++MRE Y R  +GFLIVFS+T + SFE V RF Q  LR +DR+ FPM+LVANK DL   RK+T+ +   +A +  I YIETSAK+PP+N++ AF ++VR IR  QQI
Sbjct:    7 VPGD--NLPVYKLVVVGDGGVGKSALTIQFFQKIFVPDYDPTIEDSYLKHTEIDGQWAILDVLDTAGQEEFSAMREQYMRTGDGFLIVFSVTDKASFEHVDRFHQLILRVKDRESFPMVLVANKVDLVHLRKITSEQGREMASKHSITYIETSAKDPPMNVDKAFHELVRVIR--QQI 180          
BLAST of Ras-related protein vs. Ensembl Zebrafish
Match: mras (muscle RAS oncogene homolog [Source:ZFIN;Acc:ZDB-GENE-050208-495])

HSP 1 Score: 184.111 bits (466), Expect = 2.137e-58
Identity = 89/156 (57.05%), Postives = 118/156 (75.64%), Query Frame = 3
Query:  111 KSAIILQFMQKIFVENHDPTIESTYYKNYEVDGEWSNLEVQDTAGQEEFASMRESYYRAANGFLIVFSLTTRESFEIVRRFFQSALRSRDRDHFPMLLVANKTDLEMNRKVTTSEIESLAKELQIDYIETSAKNPPINIEDAFSQIVRKIRSHQQI 578
            KSA+ +QF QKIFV ++DPTIE +Y K+ E+DG+W+ L+V DTAGQEEF++MRE Y R  +GFLIVFS+T + SFE V RF Q  LR +DR+ FPM+LVANK DL   RK+T+ +   +A +  I YIETSAK+PP+N++ AF ++VR IR  QQI
Sbjct:    2 KSALTIQFFQKIFVPDYDPTIEDSYLKHTEIDGQWAILDVLDTAGQEEFSAMREQYMRTGDGFLIVFSVTDKASFEHVDRFHQLILRVKDRESFPMVLVANKVDLVHLRKITSEQGREMASKHSITYIETSAKDPPMNVDKAFHELVRVIR--QQI 155          
BLAST of Ras-related protein vs. Ensembl Zebrafish
Match: rras2 (RAS related 2 [Source:ZFIN;Acc:ZDB-GENE-050417-352])

HSP 1 Score: 160.614 bits (405), Expect = 6.387e-49
Identity = 83/187 (44.39%), Postives = 119/187 (63.64%), Query Frame = 3
Query:  111 KSAIILQFMQKIFVENHDPTIESTYYKNYEVDGEWSNLEVQDTAGQEEFASMRESYYRAANGFLIVFSLTTRESFEIVRRFFQSALRSRDRDHFPMLLVANKTDLEMNRKVTTSEIESLAKELQIDYIETSAKNPPINIEDAFSQIVRKIRSHQQINDVKLKSRPRQKQKCCLM*KTANNNWTLCHC 671
            KSA+ +QF+Q  FV ++DPTIE +Y K   +D   + L++ DTAGQEEF +MRE Y R   GFL+VFS+T R SFE + +F +  LR +DRD FPM+LV NK DLE  R+VT  E + LA++L++ Y+E SAK   +N++ AF ++VR IR  Q+  +      P +K+K          + + CHC
Sbjct:   25 KSALTIQFIQSYFVTDYDPTIEDSYTKQCVIDERPARLDILDTAGQEEFGAMREQYMRTGEGFLLVFSVTDRGSFEEIYKFQRQILRVKDRDEFPMILVGNKADLEQQRQVTQEEGQQLARQLKVTYMEASAKI-RMNVDQAFHELVRVIRKFQE-QECPPSPEPTRKEK----------DKSGCHC 199          
BLAST of Ras-related protein vs. Ensembl Xenopus
Match: thbs3 (thrombospondin 3 [Source:Xenbase;Acc:XB-GENE-5761978])

HSP 1 Score: 182.956 bits (463), Expect = 2.088e-57
Identity = 92/168 (54.76%), Postives = 125/168 (74.40%), Query Frame = 3
Query:  111 KSAIILQFMQKIFVENHDPTIESTYYKNYEVDGEWSNLEVQDTAGQEEFASMRESYYRAANGFLIVFSLTTRESFEIVRRFFQSALRSRDRDHFPMLLVANKTDLEMNRKVTTSEIESLAKELQIDYIETSAKNPPINIEDAFSQIVRKIRSHQQINDVKLKSRPRQK 614
            KSA+ +QF QKIFV ++DPTIE +Y K+ E+DG+W+ L+V DTAGQEEF++MRE Y R  +GFLIV+S+T + SFE V RF Q  LR +DR+ FPM+LVANK DL   RKV++ + + +A +  I YIETSAK+PP N++ AF ++VR IR  QQI D   KS+ R++
Sbjct:   26 KSALTIQFFQKIFVPDYDPTIEDSYLKHTEIDGQWAILDVLDTAGQEEFSAMREQYMRTGDGFLIVYSVTDKASFEHVDRFHQLILRVKDRESFPMILVANKVDLIHLRKVSSEQGKEMATKHNIPYIETSAKDPPQNVDKAFHELVRVIR--QQIPD---KSQKRKR 188          
BLAST of Ras-related protein vs. Ensembl Xenopus
Match: tle1 (transducin like enhancer of split 1 [Source:Xenbase;Acc:XB-GENE-868100])

HSP 1 Score: 155.221 bits (391), Expect = 1.500e-46
Identity = 73/156 (46.79%), Postives = 107/156 (68.59%), Query Frame = 3
Query:  111 KSAIILQFMQKIFVENHDPTIESTYYKNYEVDGEWSNLEVQDTAGQEEFASMRESYYRAANGFLIVFSLTTRESFEIVRRFFQSALRSRDRDHFPMLLVANKTDLEMNRKVTTSEIESLAKELQIDYIETSAKNPPINIEDAFSQIVRKIRSHQQI 578
            KSA+ +QF+Q  FV ++DPTIE +Y K   +DG+ + L++ DTAGQEEF +MRE Y R   GFL++F++  R SF  + +F    LR +DRD FPM+LV NK DL++ R+VT  E  S A+E  I Y+E SAK   +N++++F ++VR IR  Q++
Sbjct:   26 KSALTIQFIQSYFVSDYDPTIEDSYTKICSIDGKQTRLDILDTAGQEEFGAMREQYMRTGEGFLLIFAINDRGSFNEMSKFHTQILRVKDRDEFPMILVGNKADLDLQRQVTKEEALSFARENHIPYMEASAKI-RLNVDESFHELVRAIRKFQEL 180          
BLAST of Ras-related protein vs. Ensembl Xenopus
Match: clca1.1 (chloride channel accessory 1 gene 1 [Source:Xenbase;Acc:XB-GENE-5838950])

HSP 1 Score: 144.05 bits (362), Expect = 4.759e-42
Identity = 85/195 (43.59%), Postives = 124/195 (63.59%), Query Frame = 3
Query:   45 LPSDLSNMSKMKXXXXXXXXXXKSAIILQFMQKIFVENHDPTIESTYYKNYEVDGEWSNLEVQDTAGQEEFASMRESYYRAANGFLIVFSLTTRESFEIVRRFFQSALRSRDRDHFPMLLVANKTDLEMNRKVTTSEIESLAKELQIDYIETSAKNPPINIEDAFSQIVRKIRSHQQINDVKLKSRPRQKQKCCL 629
            +P   S M++ K+VV+G GGVGKSA+ +Q +Q  FV+ +DPTIE +Y K   +DGE   L++ DTAGQEE+++MR+ Y R   GFL VF++   +SFE + ++ +   R +D D  PM+LV NK DL   R V T + + LA+   I YIETSAK     +EDAF  +VR+IR H+    ++  + P + +K CL
Sbjct:   22 IPRGSSTMTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHQYREQIKRVKDSDDVPMVLVGNKCDLPA-RTVETRQAQDLARSYGIPYIETSAKTRQ-GVEDAFYTLVREIRQHK----LRKLNPPDESEKGCL 210          
BLAST of Ras-related protein vs. Ensembl Xenopus
Match: clca1.1 (chloride channel accessory 1 gene 1 [Source:Xenbase;Acc:XB-GENE-5838950])

HSP 1 Score: 141.739 bits (356), Expect = 1.803e-41
Identity = 84/190 (44.21%), Postives = 122/190 (64.21%), Query Frame = 3
Query:   60 SNMSKMKXXXXXXXXXXKSAIILQFMQKIFVENHDPTIESTYYKNYEVDGEWSNLEVQDTAGQEEFASMRESYYRAANGFLIVFSLTTRESFEIVRRFFQSALRSRDRDHFPMLLVANKTDLEMNRKVTTSEIESLAKELQIDYIETSAKNPPINIEDAFSQIVRKIRSHQQINDVKLKSRPRQKQKCCL 629
            S M++ K+VV+G GGVGKSA+ +Q +Q  FV+ +DPTIE +Y K   +DGE   L++ DTAGQEE+++MR+ Y R   GFL VF++   +SFE + ++ +   R +D D  PM+LV NK DL   R V T + + LA+   I YIETSAK     +EDAF  +VR+IR H+    ++  + P + +K CL
Sbjct:    9 STMTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHQYREQIKRVKDSDDVPMVLVGNKCDLPA-RTVETRQAQDLARSYGIPYIETSAKTRQ-GVEDAFYTLVREIRQHK----LRKLNPPDESEKGCL 192          
BLAST of Ras-related protein vs. Ensembl Xenopus
Match: clca1.1 (chloride channel accessory 1 gene 1 [Source:Xenbase;Acc:XB-GENE-5838950])

HSP 1 Score: 140.584 bits (353), Expect = 4.474e-41
Identity = 83/188 (44.15%), Postives = 121/188 (64.36%), Query Frame = 3
Query:   66 MSKMKXXXXXXXXXXKSAIILQFMQKIFVENHDPTIESTYYKNYEVDGEWSNLEVQDTAGQEEFASMRESYYRAANGFLIVFSLTTRESFEIVRRFFQSALRSRDRDHFPMLLVANKTDLEMNRKVTTSEIESLAKELQIDYIETSAKNPPINIEDAFSQIVRKIRSHQQINDVKLKSRPRQKQKCCL 629
            M++ K+VV+G GGVGKSA+ +Q +Q  FV+ +DPTIE +Y K   +DGE   L++ DTAGQEE+++MR+ Y R   GFL VF++   +SFE + ++ +   R +D D  PM+LV NK DL   R V T + + LA+   I YIETSAK     +EDAF  +VR+IR H+    ++  + P + +K CL
Sbjct:    1 MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHQYREQIKRVKDSDDVPMVLVGNKCDLPA-RTVETRQAQDLARSYGIPYIETSAKTRQ-GVEDAFYTLVREIRQHK----LRKLNPPDESEKGCL 182          
BLAST of Ras-related protein vs. Ensembl Mouse
Match: Mras (muscle and microspikes RAS [Source:MGI Symbol;Acc:MGI:1100856])

HSP 1 Score: 178.333 bits (451), Expect = 9.690e-56
Identity = 98/178 (55.06%), Postives = 132/178 (74.16%), Query Frame = 3
Query:   45 LPSDLSNMSKMKXXXXXXXXXXKSAIILQFMQKIFVENHDPTIESTYYKNYEVDGEWSNLEVQDTAGQEEFASMRESYYRAANGFLIVFSLTTRESFEIVRRFFQSALRSRDRDHFPMLLVANKTDLEMNRKVTTSEIESLAKELQIDYIETSAKNPPINIEDAFSQIVRKIRSHQQI 578
            +PS+  N+   K+VV+GDGGVGKSA+ +QF QKIFV ++DPTIE +Y K+ E+D +W+ L+V DTAGQEEF++MRE Y R  +GFLIV+S+T + SFE V RF Q  LR +DR+ FPM+LVANK DL   RKVT  + + +A +  I YIETSAK+PP+N++  F  +VR IR  QQ+
Sbjct:    6 VPSE--NLPTYKLVVVGDGGVGKSALTIQFFQKIFVPDYDPTIEDSYLKHTEIDNQWAILDVLDTAGQEEFSAMREQYMRTGDGFLIVYSVTDKASFEHVDRFHQLILRVKDRESFPMILVANKVDLMHLRKVTRDQGKEMATKYNIPYIETSAKDPPLNVDKTFHDLVRVIR--QQV 179          
BLAST of Ras-related protein vs. Ensembl Mouse
Match: Mras (muscle and microspikes RAS [Source:MGI Symbol;Acc:MGI:1100856])

HSP 1 Score: 178.333 bits (451), Expect = 9.690e-56
Identity = 98/178 (55.06%), Postives = 132/178 (74.16%), Query Frame = 3
Query:   45 LPSDLSNMSKMKXXXXXXXXXXKSAIILQFMQKIFVENHDPTIESTYYKNYEVDGEWSNLEVQDTAGQEEFASMRESYYRAANGFLIVFSLTTRESFEIVRRFFQSALRSRDRDHFPMLLVANKTDLEMNRKVTTSEIESLAKELQIDYIETSAKNPPINIEDAFSQIVRKIRSHQQI 578
            +PS+  N+   K+VV+GDGGVGKSA+ +QF QKIFV ++DPTIE +Y K+ E+D +W+ L+V DTAGQEEF++MRE Y R  +GFLIV+S+T + SFE V RF Q  LR +DR+ FPM+LVANK DL   RKVT  + + +A +  I YIETSAK+PP+N++  F  +VR IR  QQ+
Sbjct:    6 VPSE--NLPTYKLVVVGDGGVGKSALTIQFFQKIFVPDYDPTIEDSYLKHTEIDNQWAILDVLDTAGQEEFSAMREQYMRTGDGFLIVYSVTDKASFEHVDRFHQLILRVKDRESFPMILVANKVDLMHLRKVTRDQGKEMATKYNIPYIETSAKDPPLNVDKTFHDLVRVIR--QQV 179          
BLAST of Ras-related protein vs. Ensembl Mouse
Match: Mras (muscle and microspikes RAS [Source:MGI Symbol;Acc:MGI:1100856])

HSP 1 Score: 178.333 bits (451), Expect = 9.690e-56
Identity = 98/178 (55.06%), Postives = 132/178 (74.16%), Query Frame = 3
Query:   45 LPSDLSNMSKMKXXXXXXXXXXKSAIILQFMQKIFVENHDPTIESTYYKNYEVDGEWSNLEVQDTAGQEEFASMRESYYRAANGFLIVFSLTTRESFEIVRRFFQSALRSRDRDHFPMLLVANKTDLEMNRKVTTSEIESLAKELQIDYIETSAKNPPINIEDAFSQIVRKIRSHQQI 578
            +PS+  N+   K+VV+GDGGVGKSA+ +QF QKIFV ++DPTIE +Y K+ E+D +W+ L+V DTAGQEEF++MRE Y R  +GFLIV+S+T + SFE V RF Q  LR +DR+ FPM+LVANK DL   RKVT  + + +A +  I YIETSAK+PP+N++  F  +VR IR  QQ+
Sbjct:    6 VPSE--NLPTYKLVVVGDGGVGKSALTIQFFQKIFVPDYDPTIEDSYLKHTEIDNQWAILDVLDTAGQEEFSAMREQYMRTGDGFLIVYSVTDKASFEHVDRFHQLILRVKDRESFPMILVANKVDLMHLRKVTRDQGKEMATKYNIPYIETSAKDPPLNVDKTFHDLVRVIR--QQV 179          
BLAST of Ras-related protein vs. Ensembl Mouse
Match: Rras2 (related RAS viral (r-ras) oncogene 2 [Source:MGI Symbol;Acc:MGI:1914172])

HSP 1 Score: 159.073 bits (401), Expect = 3.121e-48
Identity = 91/206 (44.17%), Postives = 131/206 (63.59%), Query Frame = 3
Query:   54 DLSNMSKMKXXXXXXXXXXKSAIILQFMQKIFVENHDPTIESTYYKNYEVDGEWSNLEVQDTAGQEEFASMRESYYRAANGFLIVFSLTTRESFEIVRRFFQSALRSRDRDHFPMLLVANKTDLEMNRKVTTSEIESLAKELQIDYIETSAKNPPINIEDAFSQIVRKIRSHQQINDVKLKSRPRQKQKCCLM*KTANNNWTLCHC 671
            D S   K ++VV+G GGVGKSA+ +QF+Q  FV ++DPTIE +Y K   +D   + L++ DTAGQEEF +MRE Y R   GFL+VFS+T R SFE + +F +  LR +DRD FPM+L+ NK DL+  R+VT  E + LA++L++ Y+E SAK   +N++ AF ++VR IR  Q+  +      P +K+K          +   CHC
Sbjct:    8 DGSGQEKYRLVVVGGGGVGKSALTIQFIQSYFVTDYDPTIEDSYTKQCVIDDRAARLDILDTAGQEEFGAMREQYMRTGEGFLLVFSVTDRGSFEEIYKFQRQILRVKDRDEFPMILIGNKADLDHQRQVTQEEGQQLARQLKVTYMEASAK-IRMNVDQAFHELVRVIRKFQE-QECPPSPEPTRKEK----------DKKGCHC 201          
BLAST of Ras-related protein vs. Ensembl Mouse
Match: Rras (related RAS viral (r-ras) oncogene [Source:MGI Symbol;Acc:MGI:98179])

HSP 1 Score: 158.688 bits (400), Expect = 7.585e-48
Identity = 82/173 (47.40%), Postives = 111/173 (64.16%), Query Frame = 3
Query:  111 KSAIILQFMQKIFVENHDPTIESTYYKNYEVDGEWSNLEVQDTAGQEEFASMRESYYRAANGFLIVFSLTTRESFEIVRRFFQSALRSRDRDHFPMLLVANKTDLEMNRKVTTSEIESLAKELQIDYIETSAKNPPINIEDAFSQIVRKIRSHQ-QINDVKLKSRPRQKQKCC 626
            KSA+ +QF+Q  FV ++DPTIE +Y K   VDG  + L++ DTAGQEEF +MRE Y RA NGFL+VF++  R+SF  V + F   LR +DRD FP++LV NK DLE  R+V  SE  S +    + Y E SAK   +N+++AF Q+VR +R +Q Q       S PR+K   C
Sbjct:   42 KSALTIQFIQSYFVSDYDPTIEDSYTKICTVDGIPARLDILDTAGQEEFGAMREQYMRAGNGFLLVFAINDRQSFNEVGKLFTQILRVKDRDDFPIVLVGNKADLENQRQVLRSEASSFSASHHMTYFEASAKL-RLNVDEAFEQLVRAVRKYQEQELPPSPPSAPRKKDGGC 213          
BLAST of Ras-related protein vs. UniProt/SwissProt
Match: sp|O14807|RASM_HUMAN (Ras-related protein M-Ras OS=Homo sapiens OX=9606 GN=MRAS PE=1 SV=2)

HSP 1 Score: 181.415 bits (459), Expect = 4.490e-56
Identity = 100/178 (56.18%), Postives = 133/178 (74.72%), Query Frame = 3
Query:   45 LPSDLSNMSKMKXXXXXXXXXXKSAIILQFMQKIFVENHDPTIESTYYKNYEVDGEWSNLEVQDTAGQEEFASMRESYYRAANGFLIVFSLTTRESFEIVRRFFQSALRSRDRDHFPMLLVANKTDLEMNRKVTTSEIESLAKELQIDYIETSAKNPPINIEDAFSQIVRKIRSHQQI 578
            +PSD  N+   K+VV+GDGGVGKSA+ +QF QKIFV ++DPTIE +Y K+ E+D +W+ L+V DTAGQEEF++MRE Y R  +GFLIV+S+T + SFE V RF Q  LR +DR+ FPM+LVANK DL   RK+T  + + +A +  I YIETSAK+PP+N++ AF  +VR IR  QQI
Sbjct:    6 VPSD--NLPTYKLVVVGDGGVGKSALTIQFFQKIFVPDYDPTIEDSYLKHTEIDNQWAILDVLDTAGQEEFSAMREQYMRTGDGFLIVYSVTDKASFEHVDRFHQLILRVKDRESFPMILVANKVDLMHLRKITREQGKEMATKHNIPYIETSAKDPPLNVDKAFHDLVRVIR--QQI 179          
BLAST of Ras-related protein vs. UniProt/SwissProt
Match: sp|P97538|RASM_RAT (Ras-related protein M-Ras OS=Rattus norvegicus OX=10116 GN=Mras PE=1 SV=2)

HSP 1 Score: 180.259 bits (456), Expect = 1.155e-55
Identity = 99/178 (55.62%), Postives = 132/178 (74.16%), Query Frame = 3
Query:   45 LPSDLSNMSKMKXXXXXXXXXXKSAIILQFMQKIFVENHDPTIESTYYKNYEVDGEWSNLEVQDTAGQEEFASMRESYYRAANGFLIVFSLTTRESFEIVRRFFQSALRSRDRDHFPMLLVANKTDLEMNRKVTTSEIESLAKELQIDYIETSAKNPPINIEDAFSQIVRKIRSHQQI 578
            +PSD  N+   K+VV+GDGGVGKSA+ +QF QKIFV ++DPTIE +Y K+ E+D +W+ L+V DTAGQEEF++MRE Y R  +GFLIV+S+T + SFE V RF Q  LR +DR+ FPM+LVANK DL   RKVT  + + +A +  I YIETSAK+PP+N++  F  +VR IR  QQ+
Sbjct:    6 VPSD--NLPTYKLVVVGDGGVGKSALTIQFFQKIFVPDYDPTIEDSYLKHTEIDNQWAILDVLDTAGQEEFSAMREQYMRTGDGFLIVYSVTDKASFEHVDRFHQLILRVKDRESFPMILVANKVDLMHLRKVTRDQGKEMATKYNIPYIETSAKDPPLNVDKTFHDLVRVIR--QQV 179          
BLAST of Ras-related protein vs. UniProt/SwissProt
Match: sp|O08989|RASM_MOUSE (Ras-related protein M-Ras OS=Mus musculus OX=10090 GN=Mras PE=1 SV=1)

HSP 1 Score: 178.333 bits (451), Expect = 6.778e-55
Identity = 98/178 (55.06%), Postives = 132/178 (74.16%), Query Frame = 3
Query:   45 LPSDLSNMSKMKXXXXXXXXXXKSAIILQFMQKIFVENHDPTIESTYYKNYEVDGEWSNLEVQDTAGQEEFASMRESYYRAANGFLIVFSLTTRESFEIVRRFFQSALRSRDRDHFPMLLVANKTDLEMNRKVTTSEIESLAKELQIDYIETSAKNPPINIEDAFSQIVRKIRSHQQI 578
            +PS+  N+   K+VV+GDGGVGKSA+ +QF QKIFV ++DPTIE +Y K+ E+D +W+ L+V DTAGQEEF++MRE Y R  +GFLIV+S+T + SFE V RF Q  LR +DR+ FPM+LVANK DL   RKVT  + + +A +  I YIETSAK+PP+N++  F  +VR IR  QQ+
Sbjct:    6 VPSE--NLPTYKLVVVGDGGVGKSALTIQFFQKIFVPDYDPTIEDSYLKHTEIDNQWAILDVLDTAGQEEFSAMREQYMRTGDGFLIVYSVTDKASFEHVDRFHQLILRVKDRESFPMILVANKVDLMHLRKVTRDQGKEMATKYNIPYIETSAKDPPLNVDKTFHDLVRVIR--QQV 179          
BLAST of Ras-related protein vs. UniProt/SwissProt
Match: sp|P08647|RAS_SCHPO (Ras-like protein 1 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) OX=284812 GN=ras1 PE=1 SV=2)

HSP 1 Score: 162.155 bits (409), Expect = 2.086e-48
Identity = 77/155 (49.68%), Postives = 111/155 (71.61%), Query Frame = 3
Query:  111 KSAIILQFMQKIFVENHDPTIESTYYKNYEVDGEWSNLEVQDTAGQEEFASMRESYYRAANGFLIVFSLTTRESFEIVRRFFQSALRSRDRDHFPMLLVANKTDLEMNRKVTTSEIESLAKELQIDYIETSAKNPPINIEDAFSQIVRKIRSHQQ 575
            KSA+ +Q +Q  FV+ +DPTIE +Y K  E+DGE + L+V DTAGQEE+++MRE Y R   GFL+V+++T+R SF+ +  F+Q  LR +D+D FP++LVANK DLE  R V+ +E E LAK +   Y+ETSAK   +N+E+AF  +VR IR + +
Sbjct:   21 KSALTIQLIQSHFVDEYDPTIEDSYRKKCEIDGEGALLDVLDTAGQEEYSAMREQYMRTGEGFLLVYNITSRSSFDEISTFYQQILRVKDKDTFPVVLVANKCDLEAERVVSRAEGEQLAKSMHCLYVETSAK-LRLNVEEAFYSLVRTIRRYNK 174          
BLAST of Ras-related protein vs. UniProt/SwissProt
Match: sp|P22278|RAS1_MUCCL (Ras-like protein 1 OS=Mucor circinelloides f. lusitanicus OX=29924 GN=RAS1 PE=2 SV=1)

HSP 1 Score: 160.229 bits (404), Expect = 7.335e-48
Identity = 81/181 (44.75%), Postives = 120/181 (66.30%), Query Frame = 3
Query:  111 KSAIILQFMQKIFVENHDPTIESTYYKNYEVDGEWSNLEVQDTAGQEEFASMRESYYRAANGFLIVFSLTTRESFEIVRRFFQSALRSRDRDHFPMLLVANKTDLEMNRKVTTSEIESLAKELQIDYIETSAKNPPINIEDAFSQIVRKIRSHQQINDVK------LKSRPR-QKQKCCLM 632
            KSA+ +QF+Q  FV+ +DPTIE +Y K   +D E + L+V DTAGQEE+++MRE Y R   GFL+V+S+T+R SFE +  F+Q   R +DRD+FPM+LV NK DLE +R+V++ E   LAK     +IETSAK   IN+++AF ++VR IR + +  + +      ++  P     KCC++
Sbjct:   23 KSALTIQFIQSHFVDEYDPTIEDSYRKQCVIDSETALLDVLDTAGQEEYSAMREQYMRNGEGFLLVYSITSRLSFEEITTFYQQICRVKDRDYFPMVLVGNKCDLEGDRQVSSQEGRDLAKNFGCQFIETSAKQ-RINVDEAFFEVVRDIRRYNKEQETRGHDQFGIQDAPDVASDKCCIL 202          
BLAST of Ras-related protein vs. TrEMBL
Match: A0A158QDM8 (Uncharacterized protein OS=Hymenolepis diminuta OX=6216 GN=HDID_LOCUS3327 PE=4 SV=1)

HSP 1 Score: 198.364 bits (503), Expect = 2.560e-60
Identity = 103/202 (50.99%), Postives = 148/202 (73.27%), Query Frame = 3
Query:   30 LKMPKLPSDLSNMSKMKXXXXXXXXXXKSAIILQFMQKIFVENHDPTIESTYYKNYEVDGEWSNLEVQDTAGQEEFASMRESYYRAANGFLIVFSLTTRESFEIVRRFFQSALRSRDRDHFPMLLVANKTDLEMNRKVTTSEIESLAKELQIDYIETSAKNPPINIEDAFSQIVRKIRSHQQIND--VKLKSRPRQKQKCCL 629
            + M ++P+D+S + K K+VV+GDGGVGKSA+ +Q+ Q +F+E+H+PTIE +Y +N EVDGEW  L+V DTAGQ+EF++MRE Y R  +GF+IV+S+T ++SF  VRRF+   LR+RDRD +PM+L ANK DL   R VT  + ++LA+EL + YIETSAKNPP+N++  F  ++R IR  Q ++      K RPR+ +  CL
Sbjct:    1 MAMTQIPNDISAIPKFKVVVVGDGGVGKSALTIQYFQHMFLEDHNPTIEDSYLQNVEVDGEWCVLDVLDTAGQDEFSAMREQYMRKGHGFIIVYSVTDQQSFRQVRRFYTQILRARDRDSYPMILAANKIDLVQQRVVTPEDGQNLAQELGVQYIETSAKNPPVNVDLIFHDLIRIIRK-QPVSPPLTNQKPRPRKVKCTCL 201          
BLAST of Ras-related protein vs. TrEMBL
Match: A0A068YB98 (Ras protein m ras OS=Echinococcus multilocularis OX=6211 GN=EmuJ_000952100 PE=4 SV=1)

HSP 1 Score: 198.749 bits (504), Expect = 3.896e-60
Identity = 102/201 (50.75%), Postives = 145/201 (72.14%), Query Frame = 3
Query:   30 LKMPKLPSDLSNMSKMKXXXXXXXXXXKSAIILQFMQKIFVENHDPTIESTYYKNYEVDGEWSNLEVQDTAGQEEFASMRESYYRAANGFLIVFSLTTRESFEIVRRFFQSALRSRDRDHFPMLLVANKTDLEMNRKVTTSEIESLAKELQIDYIETSAKNPPINIEDAFSQIVRKIRSH-QQINDVKLKSRPRQKQKCCL 629
            + M ++P+D+S + K K+VV+GDGGVGKSA+ +Q+ Q +F+E+H+PTIE +Y +N EVDGEW  L+V DTAGQ+EF++MRE Y R  +GF+IV+S+T ++SF  VRRF+   LR+RDRD +PM+L ANK DL   R VT  E ++LA+EL + YIETSAKNPP+N++  F  ++R IR           K RPR+K+   +
Sbjct:    1 MAMTQIPNDISAIPKFKVVVVGDGGVGKSALTIQYFQHMFLEDHNPTIEDSYLQNVEVDGEWCVLDVLDTAGQDEFSAMREQYMRKGHGFIIVYSVTDQQSFRQVRRFYTQILRARDRDSYPMILAANKIDLVQQRVVTPEEGQTLARELGVQYIETSAKNPPVNVDLIFHDLIRIIRKQPASPPPASQKRRPRKKKASVI 201          
BLAST of Ras-related protein vs. TrEMBL
Match: A0A0R3W2T2 (Uncharacterized protein OS=Taenia asiatica OX=60517 GN=TASK_LOCUS4168 PE=4 SV=1)

HSP 1 Score: 196.438 bits (498), Expect = 7.391e-60
Identity = 98/178 (55.06%), Postives = 137/178 (76.97%), Query Frame = 3
Query:   30 LKMPKLPSDLSNMSKMKXXXXXXXXXXKSAIILQFMQKIFVENHDPTIESTYYKNYEVDGEWSNLEVQDTAGQEEFASMRESYYRAANGFLIVFSLTTRESFEIVRRFFQSALRSRDRDHFPMLLVANKTDLEMNRKVTTSEIESLAKELQIDYIETSAKNPPINIEDAFSQIVRKIR 563
            + M ++P+D+S + K K+VV+GDGGVGKSA+ +Q+ Q +F+E+H+PTIE +Y +N EVDGEW  L+V DTAGQ+EF++MRE Y R  +GF+IV+S+T ++SF  VRRF+   LR+RDRD +PM+L ANK DL   R VT  E ++LA+EL I YIETSAKNPP+N++  F  ++R IR
Sbjct:    1 MAMTQIPNDISAIPKFKVVVVGDGGVGKSALTIQYFQHMFLEDHNPTIEDSYLQNIEVDGEWCVLDVLDTAGQDEFSAMRELYMRKGHGFIIVYSVTDQQSFRQVRRFYTQILRARDRDSYPMILAANKIDLVQQRVVTPEEGQTLAQELGIQYIETSAKNPPVNVDLIFHDLIRIIR 178          
BLAST of Ras-related protein vs. TrEMBL
Match: A0A0X3QGD8 (Ras-related protein M-Ras OS=Schistocephalus solidus OX=70667 GN=RASM PE=4 SV=1)

HSP 1 Score: 196.823 bits (499), Expect = 8.475e-60
Identity = 103/198 (52.02%), Postives = 144/198 (72.73%), Query Frame = 3
Query:   42 KLPSDLSNMSKMKXXXXXXXXXXKSAIILQFMQKIFVENHDPTIESTYYKNYEVDGEWSNLEVQDTAGQEEFASMRESYYRAANGFLIVFSLTTRESFEIVRRFFQSALRSRDRDHFPMLLVANKTDLEMNRKVTTSEIESLAKELQIDYIETSAKNPPINIEDAFSQIVRKIRSHQ-QINDVKLKSRPRQKQKCCLM 632
            ++P+D+S + K K+VV+GDGGVGKSA+ +Q+ Q +F+E+H+PTIE +Y +N E+DGEW  L+V DTAGQ+EF++MRE Y R  +GF++V+S+T  +SF  VRRF    LR+RDRD +P++L ANK DL   R V+  E ++LA EL + YIETSAKNPPIN++  F  +VR IR HQ     V  K RP+ K KC ++
Sbjct:    5 QIPNDISTIPKFKVVVVGDGGVGKSALTIQYFQHMFIEDHNPTIEDSYIQNVEIDGEWCVLDVLDTAGQDEFSAMREQYMRKGHGFIVVYSVTDPQSFRQVRRFHTQILRARDRDSYPVILAANKIDLVHLRVVSPEEGQALADELGVQYIETSAKNPPINVDLTFHNMVRIIRKHQSNAPPVSRKQRPK-KMKCNVL 201          
BLAST of Ras-related protein vs. TrEMBL
Match: A0A5K3EPZ4 (Uncharacterized protein OS=Mesocestoides corti OX=53468 PE=4 SV=1)

HSP 1 Score: 198.364 bits (503), Expect = 8.827e-60
Identity = 105/202 (51.98%), Postives = 146/202 (72.28%), Query Frame = 3
Query:   30 LKMPKLPSDLSNMSKMKXXXXXXXXXXKSAIILQFMQKIFVENHDPTIESTYYKNYEVDGEWSNLEVQDTAGQEEFASMRESYYRAANGFLIVFSLTTRESFEIVRRFFQSALRSRDRDHFPMLLVANKTDLEMNRKVTTSEIESLAKELQIDYIETSAKNPPINIEDAFSQIVRKIRSHQQIN--DVKLKSRPRQKQKCCL 629
            + + ++P+D+S + K K+VV+GDGGVGKSA+ +Q+ Q +F+E+H+PTIE +Y +N EVDGEW  L+V DTAGQ+EF++MRE Y R  +GF+IV+S+T  +SF  VRRF    LR+RDRD +PM+L ANK DL   R VT  E  SLA+EL + Y+ETSAKNPP+N++  F  ++R IR  Q +N   V  K RPR+ +  CL
Sbjct:   37 MALTQIPNDISAIPKFKVVVVGDGGVGKSALTIQYFQHMFLEDHNPTIEDSYIQNVEVDGEWCVLDVLDTAGQDEFSAMREQYMRKGHGFIIVYSVTDPQSFRQVRRFHTQILRARDRDSYPMILAANKIDLVQQRLVTEEEGRSLAQELGVQYVETSAKNPPVNVDLIFHDLIRIIRK-QPLNFPPVSQKQRPRKMKCTCL 237          
BLAST of Ras-related protein vs. Ensembl Cavefish
Match: si:ch73-116o1.2 (muscle RAS oncogene homolog [Source:HGNC Symbol;Acc:HGNC:7227])

HSP 1 Score: 186.422 bits (472), Expect = 5.553e-59
Identity = 100/173 (57.80%), Postives = 132/173 (76.30%), Query Frame = 3
Query:   45 LPSDLSNMSKMKXXXXXXXXXXKSAIILQFMQKIFVENHDPTIESTYYKNYEVDGEWSNLEVQDTAGQEEFASMRESYYRAANGFLIVFSLTTRESFEIVRRFFQSALRSRDRDHFPMLLVANKTDLEMNRKVTTSEIESLAKELQIDYIETSAKNPPINIEDAFSQIVRKIR 563
            +PSD  N+   K+VV+GDGGVGKSA+ +QF QKIFV ++DPTIE +Y K+ E+DG+W+ L+V DTAGQEEF++MRE Y R  +GFLIVFS+T + SFE V RF Q  LR +DR+ FPM+LVANK DL   RKVT+ +   +A +  I YIETSAK+PP+N++ AF ++VR IR
Sbjct:    6 VPSD--NLPTYKLVVVGDGGVGKSALTIQFFQKIFVPDYDPTIEDSYLKHTEIDGQWAILDVLDTAGQEEFSAMREQYMRTGDGFLIVFSVTDKASFEHVDRFHQLILRVKDRESFPMVLVANKVDLVHLRKVTSDQGCEMAAKHSITYIETSAKDPPMNVDKAFHELVRVIR 176          
BLAST of Ras-related protein vs. Ensembl Cavefish
Match: mras (ras-related protein M-Ras [Source:NCBI gene;Acc:103031239])

HSP 1 Score: 185.652 bits (470), Expect = 1.282e-58
Identity = 101/178 (56.74%), Postives = 134/178 (75.28%), Query Frame = 3
Query:   45 LPSDLSNMSKMKXXXXXXXXXXKSAIILQFMQKIFVENHDPTIESTYYKNYEVDGEWSNLEVQDTAGQEEFASMRESYYRAANGFLIVFSLTTRESFEIVRRFFQSALRSRDRDHFPMLLVANKTDLEMNRKVTTSEIESLAKELQIDYIETSAKNPPINIEDAFSQIVRKIRSHQQI 578
            +P D  N+   K+VV+GDGGVGKSA+ +QF QKIFV ++DPTIE +Y K+ E+DG+W+ L+V DTAGQEEF++MRE Y R  +GFLIVFS+T + SFE V RF Q  LR +DR+ FPM+LVANK DL   RK+T+ +   +A +  I YIETSAK+PP+N++ AF ++VR IR  QQI
Sbjct:    6 VPGD--NLPTYKLVVVGDGGVGKSALTIQFFQKIFVPDYDPTIEDSYLKHTEIDGQWAILDVLDTAGQEEFSAMREQYMRTGDGFLIVFSVTDKASFEHVDRFHQLILRVKDRESFPMVLVANKVDLVHLRKITSEQGREMAMKHSITYIETSAKDPPMNVDKAFHELVRVIR--QQI 179          
BLAST of Ras-related protein vs. Ensembl Cavefish
Match: rras2 (RAS related 2 [Source:NCBI gene;Acc:103027563])

HSP 1 Score: 159.458 bits (402), Expect = 1.776e-48
Identity = 82/187 (43.85%), Postives = 119/187 (63.64%), Query Frame = 3
Query:  111 KSAIILQFMQKIFVENHDPTIESTYYKNYEVDGEWSNLEVQDTAGQEEFASMRESYYRAANGFLIVFSLTTRESFEIVRRFFQSALRSRDRDHFPMLLVANKTDLEMNRKVTTSEIESLAKELQIDYIETSAKNPPINIEDAFSQIVRKIRSHQQINDVKLKSRPRQKQKCCLM*KTANNNWTLCHC 671
            KSA+ +QF+Q  FV ++DPTIE +Y K   +D   + L++ DTAGQEEF +MRE Y R   GFL+VFS+T R SFE + +F +  LR +DRD FPM+LV NK DLE  R+V+  E + LA++L++ Y+E SAK   +N++ AF ++VR IR  Q+  +      P +K+K          + + CHC
Sbjct:   26 KSALTIQFIQSYFVTDYDPTIEDSYTKQCVIDERPARLDILDTAGQEEFGAMREQYMRTGEGFLLVFSVTDRGSFEEIYKFQRQILRVKDRDEFPMILVGNKADLEQQRQVSQDEGQQLARQLKVTYMEASAKI-RMNVDQAFHELVRVIRKFQE-QECPPSPEPTRKEK----------DKSGCHC 200          
BLAST of Ras-related protein vs. Ensembl Cavefish
Match: rras (RAS related [Source:ZFIN;Acc:ZDB-GENE-041010-217])

HSP 1 Score: 155.606 bits (392), Expect = 6.242e-47
Identity = 78/173 (45.09%), Postives = 116/173 (67.05%), Query Frame = 3
Query:  111 KSAIILQFMQKIFVENHDPTIESTYYKNYEVDGEWSNLEVQDTAGQEEFASMRESYYRAANGFLIVFSLTTRESFEIVRRFFQSALRSRDRDHFPMLLVANKTDLEMNRKVTTSEIESLAKELQIDYIETSAKNPPINIEDAFSQIVRKIRSHQQINDVK-LKSRPRQKQKCC 626
            KSA+ +QF+Q  FV ++DPTIE +Y K   VDG+ + L++ DTAGQEEF +MRE Y R+  GFL+VF+L    S+  +++F    LR +DRD FPM+LV NK+DL+ +R V+  E    A+E +I Y+E+SAKN   N+++AF ++VR IR  Q+      L + P +++K C
Sbjct:   27 KSALTIQFIQSYFVSDYDPTIEDSYTKICTVDGKETRLDILDTAGQEEFGAMREQYMRSGEGFLLVFALNDSGSYNEIQKFHTQILRVKDRDDFPMVLVGNKSDLDQHRVVSREEAMGFARENRIHYMESSAKNRH-NVDEAFLEVVRAIRKFQETESPPMLMNSPSKQRKGC 198          
BLAST of Ras-related protein vs. Ensembl Cavefish
Match: zgc:55558 (GTPase HRas-like [Source:NCBI gene;Acc:103023536])

HSP 1 Score: 140.198 bits (352), Expect = 3.783e-41
Identity = 81/189 (42.86%), Postives = 123/189 (65.08%), Query Frame = 3
Query:   66 MSKMKXXXXXXXXXXKSAIILQFMQKIFVENHDPTIESTYYKNYEVDGEWSNLEVQDTAGQEEFASMRESYYRAANGFLIVFSLTTRESFEIVRRFFQSALRSRDRDHFPMLLVANKTDLEMNRKVTTSEIESLAKELQIDYIETSAKNPPINIEDAFSQIVRKIRSHQQINDVKLKSRPRQKQKCCLM 632
            M++ K+VV+G GGVGKSA+ +Q +Q  FV+ +DPTIE +Y K   +DGE   L++ DTAGQEE+++MR+ Y R   GFL VF++   +SFE V  + +   R +D D  PM+LV NK+DL   R V T + + LA+   I ++ETSAK     +E+AF  +VR+IR +++ N    KS+   +++C L+
Sbjct:    1 MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNVKSFEDVHLYREQINRVKDSDSVPMVLVGNKSDLS-TRTVETRQAQELARGYGIPFVETSAKTRQ-GVEEAFYSLVREIRRYKETNRSNKKSKKHTQRRCILL 187          
BLAST of Ras-related protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000000518.1 (pep scaffold:Pmarinus_7.0:GL479781:11597:21619:-1 gene:ENSPMAG00000000465.1 transcript:ENSPMAT00000000518.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 185.652 bits (470), Expect = 2.517e-59
Identity = 88/156 (56.41%), Postives = 119/156 (76.28%), Query Frame = 3
Query:  111 KSAIILQFMQKIFVENHDPTIESTYYKNYEVDGEWSNLEVQDTAGQEEFASMRESYYRAANGFLIVFSLTTRESFEIVRRFFQSALRSRDRDHFPMLLVANKTDLEMNRKVTTSEIESLAKELQIDYIETSAKNPPINIEDAFSQIVRKIRSHQQI 578
            KSA+ +QF QKIFV ++DPTIE +Y K+ E+DG+W+ L+V DTAGQEEF++MRE Y R  +GFLIV+S+T + SFE V RF Q  LR +DRD FPM+LVANK DL   RK+++ + + +A +  I YIETSAK+PP+N++ AF ++VR IR  QQI
Sbjct:   26 KSALTIQFFQKIFVVDYDPTIEDSYIKHTEIDGQWAILDVLDTAGQEEFSAMREQYMRTGDGFLIVYSVTDKASFEHVERFHQLILRVKDRDSFPMILVANKVDLMHLRKISSEQGQEMAAKYSIPYIETSAKDPPLNVDKAFQELVRVIR--QQI 179          
BLAST of Ras-related protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000005561.1 (pep scaffold:Pmarinus_7.0:GL481089:12431:17765:1 gene:ENSPMAG00000005048.1 transcript:ENSPMAT00000005561.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 185.267 bits (469), Expect = 2.815e-59
Identity = 86/151 (56.95%), Postives = 115/151 (76.16%), Query Frame = 3
Query:  111 KSAIILQFMQKIFVENHDPTIESTYYKNYEVDGEWSNLEVQDTAGQEEFASMRESYYRAANGFLIVFSLTTRESFEIVRRFFQSALRSRDRDHFPMLLVANKTDLEMNRKVTTSEIESLAKELQIDYIETSAKNPPINIEDAFSQIVRKIR 563
            KSA+ +QF QKIFV ++DPTIE +Y K+ E+DG+W+ L+V DTAGQEEF++MRE Y R  +GFLIV+S+T + SFE V RF Q  LR +DR+ FPM+LVANK DL   RK++T + + +A +  I YIETSAK PP+N++ AF Q+VR IR
Sbjct:   25 KSALTIQFFQKIFVPDYDPTIEDSYIKHAEIDGQWAILDVLDTAGQEEFSAMREQYMRTGDGFLIVYSVTDKASFEHVERFHQLILRVKDRESFPMVLVANKVDLLHLRKISTEQGQEMASKYDIPYIETSAKEPPLNVDKAFHQLVRVIR 175          
BLAST of Ras-related protein vs. Ensembl Sea Lamprey
Match: mras (muscle RAS oncogene homolog [Source:ZFIN;Acc:ZDB-GENE-050208-495])

HSP 1 Score: 177.948 bits (450), Expect = 2.366e-56
Identity = 91/188 (48.40%), Postives = 132/188 (70.21%), Query Frame = 3
Query:  111 KSAIILQFMQKIFVENHDPTIESTYYKNYEVDGEWSNLEV-QDTAGQEEFASMRESYYRAANGFLIVFSLTTRESFEIVRRFFQSALRSRDRDHFPMLLVANKTDLEMNRKVTTSEIESLAKELQIDYIETSAKNPPINIEDAFSQIVRKIRSHQQINDVKLKSRPRQKQKCCLM*KTANNNWTLCHC 671
            KSA+ +QF QKIFV ++DPTIE +Y K+ E+DG+W+ L+V  DTAGQEEF++MRE Y R  +GFLIV+S+T R SFE + +F Q  LR +D+D FPM+LVANK DL   RK+++ +   +A +  I YIETSAK+PP+N++ AF ++VR IR  +Q+ + K K R + +++     +T +     CHC
Sbjct:   26 KSALTIQFFQKIFVADYDPTIEDSYLKHTEIDGQWAILDVCLDTAGQEEFSAMREQYMRTGDGFLIVYSVTDRTSFEHIDKFHQLILRVKDKDSFPMVLVANKVDLLHLRKISSEQGRDMAAKYNIPYIETSAKDPPLNVDQAFHELVRVIR--EQVPEKKNKKREKWRRE-----RTPS---VQCHC 203          
BLAST of Ras-related protein vs. Ensembl Sea Lamprey
Match: hrasb (HRas proto-oncogene, GTPase b [Source:ZFIN;Acc:ZDB-GENE-050522-466])

HSP 1 Score: 136.732 bits (343), Expect = 1.998e-40
Identity = 68/154 (44.16%), Postives = 98/154 (63.64%), Query Frame = 3
Query:  111 KSAIILQFMQKIFVENHDPTIESTYYKNYEVDGEWSNLEVQDTAGQEEFASMRESYYRAANGFLIVFSLTTRESFEIVRRFFQSALRSRDRDHFPMLLVANKTDLEMNRKVTTSEIESLAKELQIDYIETSAKNPPINIEDAFSQIVRKIRSHQ 572
            KSA+ +Q +Q  FV+ +DPTIE +Y K   +D E   L++ DTAGQEE+++MR+ Y R   GFL VF++   +SFE + ++ +   R +D D  PM+LV NK DL   R V T + + LA+   I Y+ETSAK     +EDAF  +VR+IR H+
Sbjct:   20 KSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDSETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNSKSFEDIHQYREQIKRVKDSDDVPMVLVGNKCDLPA-RTVDTKQAQDLARSYGIPYVETSAKTRQ-GVEDAFYTLVREIRDHK 171          
BLAST of Ras-related protein vs. Ensembl Sea Lamprey
Match: ralba (v-ral simian leukemia viral oncogene homolog Ba (ras related) [Source:ZFIN;Acc:ZDB-GENE-040801-267])

HSP 1 Score: 136.732 bits (343), Expect = 2.934e-40
Identity = 70/182 (38.46%), Postives = 113/182 (62.09%), Query Frame = 3
Query:  111 KSAIILQFMQKIFVENHDPTIESTYYKNYEVDGEWSNLEVQDTAGQEEFASMRESYYRAANGFLIVFSLTTRESFEIVRRFFQSALRSRDRDHFPMLLVANKTDLEMNRKVTTSEIESLAKELQIDYIETSAKNPPINIEDAFSQIVRKIRSHQ--QINDVKLKSRP------RQKQKCCLM 632
            KSA+ LQFM   FVE+++PT   +Y K   +DGE   +++ DTAGQE++A++R++Y+R+  GFL VFS+   ESF     F +  LR ++ D  P LLV NK+DLE  R+V++ E  + A++ ++ Y+ETSAK    N++  F  ++R +R  +  +  D   K +P      R +++CCL+
Sbjct:   26 KSALTLQFMYDEFVEDYEPTKADSYRKKVVLDGEEVQIDILDTAGQEDYAAIRDNYFRSGEGFLCVFSICEHESFAATLEFREQILRVKEDDSVPFLLVGNKSDLEERRQVSSEEARARAEQWRVSYVETSAKTRA-NVDKVFFDLMRDVRKRKMDEGKDKSGKVKPNKSLLQRLRERCCLL 206          
BLAST of Ras-related protein vs. Ensembl Yeast
Match: RAS1 (GTPase involved in G-protein signaling in adenylate cyclase activation; plays a role in cell proliferation; localized to the plasma membrane; homolog of mammalian RAS proto-oncogenes; relative distribution to the nucleus increases upon DNA replication stress; RAS1 has a paralog, RAS2, that arose from the whole genome duplication [Source:SGD;Acc:S000005627])

HSP 1 Score: 139.043 bits (349), Expect = 2.955e-40
Identity = 67/151 (44.37%), Postives = 105/151 (69.54%), Query Frame = 3
Query:  111 KSAIILQFMQKIFVENHDPTIESTYYKNYEVDGEWSNLEVQDTAGQEEFASMRESYYRAANGFLIVFSLTTRESFEIVRRFFQSALRSRDRDHFPMLLVANKTDLEMNRKVTTSEIESLAKELQIDYIETSAKNPPINIEDAFSQIVRKIR 563
            KSA+ +QF+Q  FV+ +DPTIE +Y K   +D + S L++ DTAGQEE+++MRE Y R   GFL+V+S+T+R SF+ +  ++Q   R +D D+ P+++V NK DLE  R+V+  +   LAK+L   ++ETSAK   IN+++AF  ++R +R
Sbjct:   23 KSALTIQFIQSYFVDEYDPTIEDSYRKQVVIDDKVSILDILDTAGQEEYSAMREQYMRTGEGFLLVYSVTSRNSFDELLSYYQQIQRVKDSDYIPVVVVGNKLDLENERQVSYEDGLRLAKQLNAPFLETSAK-QAINVDEAFYSLIRLVR 172          
BLAST of Ras-related protein vs. Ensembl Yeast
Match: RAS2 (GTP-binding protein; regulates nitrogen starvation response, sporulation, and filamentous growth; farnesylation and palmitoylation required for activity and localization to plasma membrane; homolog of mammalian Ras proto-oncogenes; RAS2 has a paralog, RAS1, that arose from the whole genome duplication [Source:SGD;Acc:S000005042])

HSP 1 Score: 138.658 bits (348), Expect = 6.250e-40
Identity = 75/173 (43.35%), Postives = 121/173 (69.94%), Query Frame = 3
Query:   45 LPSDLSNMSKMKXXXXXXXXXXKSAIILQFMQKIFVENHDPTIESTYYKNYEVDGEWSNLEVQDTAGQEEFASMRESYYRAANGFLIVFSLTTRESFEIVRRFFQSALRSRDRDHFPMLLVANKTDLEMNRKVTTSEIESLAKELQIDYIETSAKNPPINIEDAFSQIVRKIR 563
            +P + SN+ + K+VV+G GGVGKSA+ +Q  Q  FV+ +DPTIE +Y K   +D E S L++ DTAGQEE+++MRE Y R   GFL+V+S+T++ S + +  ++Q  LR +D D+ P+++V NK+DLE  ++V+  +  ++AK++   ++ETSAK   IN+E+AF  + R +R
Sbjct:    1 MPLNKSNIREYKLVVVGGGGVGKSALTIQLTQSHFVDEYDPTIEDSYRKQVVIDDEVSILDILDTAGQEEYSAMREQYMRNGEGFLLVYSITSKSSLDELMTYYQQILRVKDTDYVPIVVVGNKSDLENEKQVSYQDGLNMAKQMNAPFLETSAK-QAINVEEAFYTLARLVR 172          
BLAST of Ras-related protein vs. Ensembl Yeast
Match: RSR1 (GTP-binding protein of the Ras superfamily; required for bud site selection, morphological changes in response to mating pheromone, and efficient cell fusion; localized to the plasma membrane; significantly similar to mammalian Rap GTPases [Source:SGD;Acc:S000003384])

HSP 1 Score: 114.775 bits (286), Expect = 2.318e-31
Identity = 59/151 (39.07%), Postives = 96/151 (63.58%), Query Frame = 3
Query:  111 KSAIILQFMQKIFVENHDPTIESTYYKNYEVDGEWSNLEVQDTAGQEEFASMRESYYRAANGFLIVFSLTTRESFEIVRRFFQSALRSRDRDHFPMLLVANKTDLEMNRKVTTSE-IESLAKELQIDYIETSAKNPPINIEDAFSQIVRKI 560
            KS + +QF+Q ++++ +DPTIE +Y K  E+D +  +LE+ DTAG  +F +MRE Y ++  GFL+V+S+T R+S E +    +  LR +D D  PM+L+ NK DL   R ++  E IE  +K  ++ + ETSA     N+++ F  +VR+I
Sbjct:   16 KSCLTVQFVQGVYLDTYDPTIEDSYRKTIEIDNKVFDLEILDTAGIAQFTAMRELYIKSGMGFLLVYSVTDRQSLEELMELREQVLRIKDSDRVPMVLIGNKADLINERVISVEEGIEVSSKWGRVPFYETSALLRS-NVDEVFVDLVRQI 165          
BLAST of Ras-related protein vs. Ensembl Yeast
Match: SEC4 (Rab family GTPase; essential for vesicle-mediated exocytic secretion and autophagy; associates with the exocyst component Sec15p and may regulate polarized delivery of transport vesicles to the exocyst at the plasma membrane [Source:SGD;Acc:S000001889])

HSP 1 Score: 90.5077 bits (223), Expect = 1.313e-22
Identity = 66/184 (35.87%), Postives = 112/184 (60.87%), Query Frame = 3
Query:   69 SKMKXXXXXXXXXXKSAIILQFMQKIFVENHDPTIESTY-YKNYEVDGEWSNLEVQDTAGQEEFASMRESYYRAANGFLIVFSLTTRESFEIVRRFFQSALRSRDRDHFPMLLVANKTDLEMNRKVTTSEIESLAKELQIDYIETSAKNPPINIEDAFSQIVRKIRSHQQINDVKLKSRPRQKQ 617
            S MKI++IGD GVGKS ++++F++  F  +   TI   +  K  +++G+   L++ DTAGQE F ++  +YYR A G ++V+ +T   +F  ++++F++ +     D   +LLV NK+D+E  R VT  + E+LAKEL I +IE+SAKN   N+ + F  + + I   ++I+  KL      K+
Sbjct:   19 SIMKILLIGDSGVGKSCLLVRFVEDKFNPSFITTIGIDFKIKTVDINGKKVKLQLWDTAGQERFRTITTAYYRGAMGIILVYDVTDERTFTNIKQWFKT-VNEHANDEAQLLLVGNKSDME-TRVVTADQGEALAKELGIPFIESSAKNDD-NVNEIFFTLAKLI--QEKIDSNKLVGVGNGKE 197          
BLAST of Ras-related protein vs. Ensembl Yeast
Match: YPT1 (Rab family GTPase; involved in the ER-to-Golgi step of the secretory pathway; complex formation with the Rab escort protein Mrs6p is required for prenylation of Ypt1p by type II protein geranylgeranyltransferase (Bet2p-Bet4p); binds to unspliced HAC1 mRNA; regulates the unfolded protein response (UPR) by promoting the decay of HAC1 RNA; localizes to the early Golgi, the transitional Golgi and ER membranes, pre-autophagosomal structures, and cytoplasmic vesicles [Source:SGD;Acc:S000001856])

HSP 1 Score: 89.3521 bits (220), Expect = 2.744e-22
Identity = 60/188 (31.91%), Postives = 96/188 (51.06%), Query Frame = 3
Query:  111 KSAIILQFMQKIFVENHDPTIESTY-YKNYEVDGEWSNLEVQDTAGQEEFASMRESYYRAANGFLIVFSLTTRESFEIVRRFFQSALRSRDRDHFPMLLVANKTDLEMNRKVTTSEIESLAKELQIDYIETSAKNPPINIEDAFSQIVRKIR---SHQQIN------------DVKLKSRPRQKQKCC 626
            KS ++L+F    +  ++  TI   +  K  E+DG+   L++ DTAGQE F ++  SYYR ++G +IV+ +T +ESF  V+ + Q   R         LLV NK DL+  R V     +  A   ++ ++ETSA +   N+EDAF  + R+I+   S Q +N            ++K +S       CC
Sbjct:   21 KSCLLLRFSDDTYTNDYISTIGVDFKIKTVELDGKTVKLQIWDTAGQERFRTITSSYYRGSHGIIIVYDVTDQESFNGVKMWLQEIDRYATSTVLK-LLVGNKCDLKDKRVVEYDVAKEFADANKMPFLETSALDST-NVEDAFLTMARQIKESMSQQNLNETTQKKEDKGNVNLKGQSLTNTGGGCC 206          
BLAST of Ras-related protein vs. Ensembl Nematostella
Match: EDO39171 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SAS1])

HSP 1 Score: 159.073 bits (401), Expect = 8.044e-49
Identity = 79/174 (45.40%), Postives = 116/174 (66.67%), Query Frame = 3
Query:  111 KSAIILQFMQKIFVENHDPTIESTYYKNYEVDGEWSNLEVQDTAGQEEFASMRESYYRAANGFLIVFSLTTRESFEIVRRFFQSALRSRDRDHFPMLLVANKTDLEMNRKVTTSEIESLAKELQIDYIETSAKNPPINIEDAFSQIVRKIRSHQQINDVKLKSRPRQKQKCCLM 632
            KSA+ +QF+Q  FV ++DPTIE +Y K   +D   ++L++ DTAGQEEF++MRE Y R+  GFL+VFS+T R SFE + +F+   LR +DR  FPM++  NK+DLE  R V+T+E + LA++L+I Y+ETSAK    N++ AF  +VR IR      +   K +   K KC ++
Sbjct:   24 KSALTIQFIQSHFVSDYDPTIEDSYRKQCVIDERVAHLDILDTAGQEEFSAMREQYMRSGEGFLLVFSVTDRSSFEEINKFYNQILRVKDRTEFPMIICGNKSDLEYERTVSTAEGQELARQLRIQYLETSAKQ-RTNVDQAFHDLVRAIRRFTVATEAPPKDKKSGK-KCTIL 195          
BLAST of Ras-related protein vs. Ensembl Nematostella
Match: EDO39047 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SB93])

HSP 1 Score: 137.502 bits (345), Expect = 1.260e-40
Identity = 72/175 (41.14%), Postives = 111/175 (63.43%), Query Frame = 3
Query:  111 KSAIILQFMQKIFVENHDPTIESTYYKNYEVDGEWSNLEVQDTAGQEEFASMRESYYRAANGFLIVFSLTTRESFEIVRRFFQSALRSRDRDHFPMLLVANKTDLEMNRKVTTSEIESLAKEL-QIDYIETSAKNPPINIEDAFSQIVRKIRSHQQINDVKLKSRPRQKQKCCLM 632
            KSA+ +QF+Q IFVE +DPTIE +Y K  EVDG+   LE+ DTAG E+F +MR+ Y +   GF++V+S+T + +F  ++   +  LR +D D  PM+LV NK DLE  R V   + ++LAK+     ++ETSAK   IN+ + F  +VR      QIN    +++ R+K++ C++
Sbjct:   16 KSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDGQQCMLEILDTAGTEQFTAMRDLYMKNGQGFVLVYSITAQSTFNDLQDLREQILRVKDTDDVPMVLVGNKCDLEDERVVGKDQGQNLAKQFANCTFLETSAK-AKINVNEIFYDLVR------QINRKTPETKSRKKKRGCVL 183          
BLAST of Ras-related protein vs. Ensembl Nematostella
Match: EDO45827 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RRV2])

HSP 1 Score: 134.42 bits (337), Expect = 3.561e-39
Identity = 68/154 (44.16%), Postives = 101/154 (65.58%), Query Frame = 3
Query:  111 KSAIILQFMQKIFVENHDPTIESTYYKNYEVDGEWSNLEVQDTAGQEEFASMRESYYRAANGFLIVFSLTTRESFEIVRRFFQSALRSRDRDHFPMLLVANKTDLEMNRKVTTSEIESLAKELQIDYIETSAKNPPINIEDAFSQIVRKIRSHQ 572
            KSA+ LQFM + FVE+++PT   +Y K   +DGE   +++ DTAGQE++A++R++Y+R+  GFL VFS+T  ESF     F +  LR +  D  P LLV NK+DL   R+VT+ E +S A E  + Y+ETSAK    N++  F  ++R+IRS +
Sbjct:   24 KSALTLQFMYEEFVEDYEPTKADSYRKKAILDGEECQIDILDTAGQEDYAAIRDNYFRSGEGFLCVFSITEPESFAATTEFREQILRVKGDDKIPFLLVGNKSDLTDKRQVTSEEGQSKADEWGVPYVETSAKTRS-NVDKVFFDLMREIRSRK 176          
BLAST of Ras-related protein vs. Ensembl Nematostella
Match: EDO32914 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7STP5])

HSP 1 Score: 130.954 bits (328), Expect = 4.952e-38
Identity = 76/166 (45.78%), Postives = 111/166 (66.87%), Query Frame = 3
Query:   66 MSKMKXXXXXXXXXXKSAIILQFMQKIFVENHDPTIESTYYKNYEVDGEWSNLEVQDTAGQEEFASMRESYYRAANGFLIVFSLTTRESFEIVRRFFQSALRSRDRDHFPMLLVANKTDLEMNRKVTTSEIESLAKELQIDYIETSAKNPPINIEDAFSQIVRKIR 563
            M++ K+VV+G GGVGKSA+ +Q +Q  FV+ +DPTIE +Y K   +DGE   L++ DTAGQEE+++MR+ Y R   GFL VF++   +SFE + ++ +   R +D +  PM+LV NK DL   R V+TS+ + LAK   I + ETSAK     ++DAF  +VR+IR
Sbjct:    1 MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAVNNSKSFEDINQYREQIKRVKDAEEVPMVLVGNKCDLP-QRTVSTSDAQELAKSYNIPFQETSAKTRQ-GVDDAFYTLVREIR 164          
BLAST of Ras-related protein vs. Ensembl Nematostella
Match: EDO36396 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SIQ7])

HSP 1 Score: 126.331 bits (316), Expect = 4.059e-36
Identity = 65/151 (43.05%), Postives = 92/151 (60.93%), Query Frame = 3
Query:  111 KSAIILQFMQKIFVENHDPTIESTYYKNYEVDGEWSNLEVQDTAGQEEFASMRESYYRAANGFLIVFSLTTRESFEIVRRFFQSALRSRDRDHFPMLLVANKTDLEMNRKVTTSEIESLAKELQIDYIETSAKNPPINIEDAFSQIVRKIR 563
            KSA+I+Q +   F++ HDPTIE  Y     +D E + L++ DTAGQ+EF +MRE Y R   GF+I++S+T R SF +  ++     R R  D  P++LV NK DLE  R+VTT E + LA      + ETSA      ++DAF  +VR+IR
Sbjct:   13 KSALIVQLISHQFLDYHDPTIEDAYQHQVVLDNEPALLDILDTAGQQEFTAMREQYMRNGEGFIIIYSITDRSSFNLAAQYKDQIERVRRTDDIPIVLVGNKDDLEGKREVTTQEGQELAHRFDCPFFETSACQRHF-VDDAFHGLVREIR 162          
BLAST of Ras-related protein vs. Ensembl Medaka
Match: si:ch73-116o1.2 (muscle RAS oncogene homolog [Source:NCBI gene;Acc:101159234])

HSP 1 Score: 188.734 bits (478), Expect = 7.459e-60
Identity = 103/183 (56.28%), Postives = 136/183 (74.32%), Query Frame = 3
Query:   30 LKMPKLPSDLSNMSKMKXXXXXXXXXXKSAIILQFMQKIFVENHDPTIESTYYKNYEVDGEWSNLEVQDTAGQEEFASMRESYYRAANGFLIVFSLTTRESFEIVRRFFQSALRSRDRDHFPMLLVANKTDLEMNRKVTTSEIESLAKELQIDYIETSAKNPPINIEDAFSQIVRKIRSHQQI 578
            + M  +PSD  N+   K+VV+GDGGVGKSA+ +QF QKIFV ++DPTIE +Y K+ E+DG+W+ L+V DTAGQEEF++MRE Y R  +GFLIVFS+T + SFE V RF Q  LR +DR+ FPM+LVANK DL   RKVT  +   +A +  I YIETSAK+PP+N++ AF ++VR IR  QQ+
Sbjct:    1 MAMSAVPSD--NLPTYKLVVVGDGGVGKSALTIQFFQKIFVPDYDPTIEDSYLKHTEIDGQWAILDVLDTAGQEEFSAMREQYMRTGDGFLIVFSVTDKASFEHVDRFHQLILRVKDREAFPMVLVANKVDLVHLRKVTAEQGHEMAAKHNITYIETSAKDPPMNVDKAFHELVRVIR--QQV 179          
BLAST of Ras-related protein vs. Ensembl Medaka
Match: rras2 (RAS related 2 [Source:NCBI gene;Acc:101162668])

HSP 1 Score: 161.384 bits (407), Expect = 2.998e-49
Identity = 84/187 (44.92%), Postives = 119/187 (63.64%), Query Frame = 3
Query:  111 KSAIILQFMQKIFVENHDPTIESTYYKNYEVDGEWSNLEVQDTAGQEEFASMRESYYRAANGFLIVFSLTTRESFEIVRRFFQSALRSRDRDHFPMLLVANKTDLEMNRKVTTSEIESLAKELQIDYIETSAKNPPINIEDAFSQIVRKIRSHQQINDVKLKSRPRQKQKCCLM*KTANNNWTLCHC 671
            KSA+ +QF+Q  FV ++DPTIE +Y K   +D   + L++ DTAGQEEF +MRE Y R   GFL+VFS+T R SFE + +F +  LR +DRD FPM+LV NK DLE+ R+V   E ++LA++L++ Y+E SAK   +N++ AF ++VR IR  Q+  D      P +K+K          N   CHC
Sbjct:   25 KSALTIQFIQSYFVTDYDPTIEDSYTKQCVIDERAARLDILDTAGQEEFGAMREQYMRTGEGFLLVFSVTDRGSFEEIYKFQRQILRVKDRDEFPMILVGNKADLEIQRQVNQEEGQNLARQLKVTYMEASAK-IRMNVDQAFHELVRVIRKFQE-QDCPPSPEPTRKEK----------NKRGCHC 199          
BLAST of Ras-related protein vs. Ensembl Medaka
Match: rras (ras-related protein R-Ras [Source:NCBI gene;Acc:101174431])

HSP 1 Score: 154.066 bits (388), Expect = 1.887e-46
Identity = 78/179 (43.58%), Postives = 116/179 (64.80%), Query Frame = 3
Query:  111 KSAIILQFMQKIFVENHDPTIESTYYKNYEVDGEWSNLEVQDTAGQEEFASMRESYYRAANGFLIVFSLTTRESFEIVRRFFQSALRSRDRDHFPMLLVANKTDLEMNRKVTTSEIESLAKELQIDYIETSAKNPPINIEDAFSQIVRKIRSHQQINDVKLKSRPRQKQK-----CCLM 632
            KSA+ +QF+Q  FV ++DPTIE +Y K   VDG+ + L++ DTAGQEEF +MRE Y R+  GFL+VF+L  R S+  V++F    LR +DRD FPMLLV NK DLE  R +++ + ++ A+E +I Y+E SAKN   N+++ F ++V  IR   ++     +++   KQK     C L+
Sbjct:   19 KSALTIQFIQSYFVSDYDPTIEDSYTKVCTVDGKETRLDILDTAGQEEFGAMREQYMRSGEGFLLVFALNDRGSYHEVQKFHTQILRVKDRDDFPMLLVGNKADLEQQRVISSEDAQAFARENRIHYMEASAKN-RYNVDEVFLKLVHIIRRFHEMESPPPQAQHAGKQKSGGCPCVLL 196          
BLAST of Ras-related protein vs. Ensembl Medaka
Match: hrasb (HRas proto-oncogene, GTPase [Source:NCBI gene;Acc:101165278])

HSP 1 Score: 139.428 bits (350), Expect = 6.200e-41
Identity = 70/154 (45.45%), Postives = 100/154 (64.94%), Query Frame = 3
Query:  111 KSAIILQFMQKIFVENHDPTIESTYYKNYEVDGEWSNLEVQDTAGQEEFASMRESYYRAANGFLIVFSLTTRESFEIVRRFFQSALRSRDRDHFPMLLVANKTDLEMNRKVTTSEIESLAKELQIDYIETSAKNPPINIEDAFSQIVRKIRSHQ 572
            KSA+ +Q +Q  FV+ +DPTIE +Y K   +DGE   L++ DTAGQEE+++MR+ Y R   GFL VF++   +SFE + ++ +   R +D D  PM+LV NK DL + R V T + + LA+   I YIETSAK     +EDAF  +VR+IR H+
Sbjct:   16 KSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHQYREQIKRVKDSDDVPMVLVGNKCDLPV-RTVETRQAQELARSYGIPYIETSAKTRQ-GVEDAFYTLVREIRQHK 167          
BLAST of Ras-related protein vs. Ensembl Medaka
Match: hrasb (HRas proto-oncogene, GTPase [Source:NCBI gene;Acc:101165278])

HSP 1 Score: 139.428 bits (350), Expect = 6.200e-41
Identity = 70/154 (45.45%), Postives = 100/154 (64.94%), Query Frame = 3
Query:  111 KSAIILQFMQKIFVENHDPTIESTYYKNYEVDGEWSNLEVQDTAGQEEFASMRESYYRAANGFLIVFSLTTRESFEIVRRFFQSALRSRDRDHFPMLLVANKTDLEMNRKVTTSEIESLAKELQIDYIETSAKNPPINIEDAFSQIVRKIRSHQ 572
            KSA+ +Q +Q  FV+ +DPTIE +Y K   +DGE   L++ DTAGQEE+++MR+ Y R   GFL VF++   +SFE + ++ +   R +D D  PM+LV NK DL + R V T + + LA+   I YIETSAK     +EDAF  +VR+IR H+
Sbjct:   16 KSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHQYREQIKRVKDSDDVPMVLVGNKCDLPV-RTVETRQAQELARSYGIPYIETSAKTRQ-GVEDAFYTLVREIRQHK 167          
BLAST of Ras-related protein vs. Planmine SMEST
Match: SMESG000024796.1 (SMESG000024796.1)

HSP 1 Score: 369.392 bits (947), Expect = 1.418e-131
Identity = 189/189 (100.00%), Postives = 189/189 (100.00%), Query Frame = 3
Query:   66 MSKMKXXXXXXXXXXKSAIILQFMQKIFVENHDPTIESTYYKNYEVDGEWSNLEVQDTAGQEEFASMRESYYRAANGFLIVFSLTTRESFEIVRRFFQSALRSRDRDHFPMLLVANKTDLEMNRKVTTSEIESLAKELQIDYIETSAKNPPINIEDAFSQIVRKIRSHQQINDVKLKSRPRQKQKCCLM 632
            MSKMKIVVIGDGGVGKSAIILQFMQKIFVENHDPTIESTYYKNYEVDGEWSNLEVQDTAGQEEFASMRESYYRAANGFLIVFSLTTRESFEIVRRFFQSALRSRDRDHFPMLLVANKTDLEMNRKVTTSEIESLAKELQIDYIETSAKNPPINIEDAFSQIVRKIRSHQQINDVKLKSRPRQKQKCCLM
Sbjct:    1 MSKMKIVVIGDGGVGKSAIILQFMQKIFVENHDPTIESTYYKNYEVDGEWSNLEVQDTAGQEEFASMRESYYRAANGFLIVFSLTTRESFEIVRRFFQSALRSRDRDHFPMLLVANKTDLEMNRKVTTSEIESLAKELQIDYIETSAKNPPINIEDAFSQIVRKIRSHQQINDVKLKSRPRQKQKCCLM 189          
BLAST of Ras-related protein vs. Planmine SMEST
Match: SMESG000075044.1 (SMESG000075044.1)

HSP 1 Score: 166.777 bits (421), Expect = 1.946e-51
Identity = 77/151 (50.99%), Postives = 116/151 (76.82%), Query Frame = 3
Query:  111 KSAIILQFMQKIFVENHDPTIESTYYKNYEVDGEWSNLEVQDTAGQEEFASMRESYYRAANGFLIVFSLTTRESFEIVRRFFQSALRSRDRDHFPMLLVANKTDLEMNRKVTTSEIESLAKELQIDYIETSAKNPPINIEDAFSQIVRKIR 563
            K+A+ +Q+ Q+ FVE++DPTIE TY ++ E DGEW +L V DTAGQ+ F++MR+ Y R  +GFL++FS+T R SF++VR  ++  LR++D+++FP+++V NK DL   RKVT  E + LAKEL + Y+ETSAK PP+N+++AF ++VR IR
Sbjct:   28 KTALTIQYFQRTFVEDYDPTIEDTYIQSKEFDGEWCDLTVLDTAGQDSFSAMRQQYMRKGDGFLVMFSITDRNSFQMVRHLYKDILRTKDKENFPVIIVGNKVDLAEERKVTEEEAKELAKELNVQYMETSAKPPPVNVDNAFLEVVRLIR 178          
BLAST of Ras-related protein vs. Planmine SMEST
Match: SMESG000017314.1 (SMESG000017314.1)

HSP 1 Score: 140.584 bits (353), Expect = 1.601e-41
Identity = 74/175 (42.29%), Postives = 110/175 (62.86%), Query Frame = 3
Query:  111 KSAIILQFMQKIFVENHDPTIESTYYKNYEVDGEWSNLEVQDTAGQEEFASMRESYYRAANGFLIVFSLTTRESFEIVRRFFQSALRSRDRDHFPMLLVANKTDLEMNRKVTTSEIESLAKELQIDYIETSAKNPPINIEDAFSQIVRKIRSHQQIN-DVKLKSRPRQKQKCCLM 632
            KSA+ +QF+Q IFVE +DPTIE +Y K  EVDG    LE+ DTAG E+F +MR+ Y +   GF++V+S+T + SF  +    +  LR +D D+ PM+LV NK DLE +R V   + + LA++    ++ETSAKN  IN+ + F  +VR+I      + DVK     ++K+ C L+
Sbjct:   16 KSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDGSQCMLEILDTAGTEQFTAMRDLYMKNGQGFVLVYSITAQSSFNELEDLREQILRVKDTDNVPMVLVGNKCDLEDDRSVGKEQGQVLARKFNCSFMETSAKN-KINVNEIFYDLVRQINKQAPTSKDVK-----KRKKTCNLL 184          
BLAST of Ras-related protein vs. Planmine SMEST
Match: SMESG000075225.1 (SMESG000075225.1)

HSP 1 Score: 127.102 bits (318), Expect = 2.544e-36
Identity = 74/163 (45.40%), Postives = 108/163 (66.26%), Query Frame = 3
Query:   66 MSKMKXXXXXXXXXXKSAIILQFMQKIFVENHDPTIESTYYKNYEVDGEWSNLEVQDTAGQEEFASMRESYYRAANGFLIVFSLTTRESFEIVRRFFQSALRSRDRDHFPMLLVANKTDLEMNRKVTTSEIESLAKELQIDYIETSAKNPPINIEDAFSQIVR 554
            MS+ KIVV+G GGVGKSA+ +Q +Q  FVE +DPTIE +Y K   +DGE   L++ DTAGQEE+++MR+ Y R   GFL VF++  ++SFE +  +     R +D +  PM+LV NK DL  NR V  +  +++A++  I Y+ETSAK     +++AF  +VR
Sbjct:    1 MSEYKIVVVGAGGVGKSALTIQLIQNHFVEEYDPTIEDSYRKQMMIDGETCQLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAVNNQKSFEEIPNYRDRVKRVKDAEEIPMVLVGNKVDL-ANRTVIKTTGKAMAEDFSIPYVETSAKTRE-GVDEAFYTLVR 161          
BLAST of Ras-related protein vs. Planmine SMEST
Match: SMESG000016219.1 (SMESG000016219.1)

HSP 1 Score: 125.561 bits (314), Expect = 1.695e-35
Identity = 63/158 (39.87%), Postives = 96/158 (60.76%), Query Frame = 3
Query:  111 KSAIILQFMQKIFVENHDPTIESTYYKNYEVDGEWSNLEVQDTAGQEEFASMRESYYRAANGFLIVFSLTTRESFEIVRRFFQSALRSRDRDHFPMLLVANKTDLEMNRKVTTSEIESLAKELQIDYIETSAKNPPINIEDAFSQIVRKIRSHQQIND 584
            KSA+ LQFM + FVE+++PT   +Y K    DGE   +++ DTAGQE++  +R+ Y+R   GF+ VFS+T   S E    F +  LR +  ++ P +LV NK DL     VT+ E   LA +  +DYIETSAK    N++  + Q++R I++H++  D
Sbjct:   24 KSALTLQFMYEEFVEDYEPTKADSYRKKIMFDGEEVQIDILDTAGQEDYVGIRDHYFRTGEGFMCVFSITDHASLEAASEFREQILRVKSNENVPFILVGNKIDLRSQSVVTSEEARELANKWNVDYIETSAKTKE-NVDRVYFQLLRDIQAHKKEKD 180          
The following BLAST results are available for this feature:
BLAST of Ras-related protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
MRAS9.350e-5756.18muscle RAS oncogene homolog [Source:HGNC Symbol;Ac... [more]
MRAS9.350e-5756.18muscle RAS oncogene homolog [Source:HGNC Symbol;Ac... [more]
MRAS9.350e-5756.18muscle RAS oncogene homolog [Source:HGNC Symbol;Ac... [more]
RRAS24.545e-4844.17RAS related 2 [Source:HGNC Symbol;Acc:HGNC:17271][more]
RRAS2.986e-4746.24RAS related [Source:HGNC Symbol;Acc:HGNC:10447][more]
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BLAST of Ras-related protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ras-28.314e-5448.97GTP binding protein; R-RAS related [Source:UniPro... [more]
ras-28.314e-5448.97GTP binding protein; R-RAS related [Source:UniPro... [more]
ras-11.573e-4747.65GTP binding protein; R-RAS related; R-ras1 homolog... [more]
let-603.062e-4041.38Ras protein let-60 [Source:UniProtKB/Swiss-Prot;A... [more]
rap-17.880e-4042.29Ras-related protein Rap-1 [Source:UniProtKB/Swiss... [more]
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BLAST of Ras-related protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Ras64B2.095e-4643.41gene:FBgn0003206 transcript:FBtr0073212[more]
Rala2.282e-4039.66gene:FBgn0015286 transcript:FBtr0070582[more]
Rap12.704e-3944.00gene:FBgn0004636 transcript:FBtr0303154[more]
Rap12.704e-3944.00gene:FBgn0004636 transcript:FBtr0072867[more]
Rap12.704e-3944.00gene:FBgn0004636 transcript:FBtr0332671[more]
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BLAST of Ras-related protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
si:ch73-116o1.21.546e-5857.30si:ch73-116o1.2 [Source:ZFIN;Acc:ZDB-GENE-110411-6... [more]
MRAS1.546e-5857.30si:ch73-116o1.2 [Source:ZFIN;Acc:ZDB-GENE-110411-6... [more]
mras1.797e-5856.74muscle RAS oncogene homolog [Source:ZFIN;Acc:ZDB-G... [more]
mras2.137e-5857.05muscle RAS oncogene homolog [Source:ZFIN;Acc:ZDB-G... [more]
rras26.387e-4944.39RAS related 2 [Source:ZFIN;Acc:ZDB-GENE-050417-352... [more]
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BLAST of Ras-related protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
thbs32.088e-5754.76thrombospondin 3 [Source:Xenbase;Acc:XB-GENE-57619... [more]
tle11.500e-4646.79transducin like enhancer of split 1 [Source:Xenbas... [more]
clca1.14.759e-4243.59chloride channel accessory 1 gene 1 [Source:Xenbas... [more]
clca1.11.803e-4144.21chloride channel accessory 1 gene 1 [Source:Xenbas... [more]
clca1.14.474e-4144.15chloride channel accessory 1 gene 1 [Source:Xenbas... [more]
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BLAST of Ras-related protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Mras9.690e-5655.06muscle and microspikes RAS [Source:MGI Symbol;Acc:... [more]
Mras9.690e-5655.06muscle and microspikes RAS [Source:MGI Symbol;Acc:... [more]
Mras9.690e-5655.06muscle and microspikes RAS [Source:MGI Symbol;Acc:... [more]
Rras23.121e-4844.17related RAS viral (r-ras) oncogene 2 [Source:MGI S... [more]
Rras7.585e-4847.40related RAS viral (r-ras) oncogene [Source:MGI Sym... [more]
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BLAST of Ras-related protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|O14807|RASM_HUMAN4.490e-5656.18Ras-related protein M-Ras OS=Homo sapiens OX=9606 ... [more]
sp|P97538|RASM_RAT1.155e-5555.62Ras-related protein M-Ras OS=Rattus norvegicus OX=... [more]
sp|O08989|RASM_MOUSE6.778e-5555.06Ras-related protein M-Ras OS=Mus musculus OX=10090... [more]
sp|P08647|RAS_SCHPO2.086e-4849.68Ras-like protein 1 OS=Schizosaccharomyces pombe (s... [more]
sp|P22278|RAS1_MUCCL7.335e-4844.75Ras-like protein 1 OS=Mucor circinelloides f. lusi... [more]
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BLAST of Ras-related protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A158QDM82.560e-6050.99Uncharacterized protein OS=Hymenolepis diminuta OX... [more]
A0A068YB983.896e-6050.75Ras protein m ras OS=Echinococcus multilocularis O... [more]
A0A0R3W2T27.391e-6055.06Uncharacterized protein OS=Taenia asiatica OX=6051... [more]
A0A0X3QGD88.475e-6052.02Ras-related protein M-Ras OS=Schistocephalus solid... [more]
A0A5K3EPZ48.827e-6051.98Uncharacterized protein OS=Mesocestoides corti OX=... [more]
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BLAST of Ras-related protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
si:ch73-116o1.25.553e-5957.80muscle RAS oncogene homolog [Source:HGNC Symbol;Ac... [more]
mras1.282e-5856.74ras-related protein M-Ras [Source:NCBI gene;Acc:10... [more]
rras21.776e-4843.85RAS related 2 [Source:NCBI gene;Acc:103027563][more]
rras6.242e-4745.09RAS related [Source:ZFIN;Acc:ZDB-GENE-041010-217][more]
zgc:555583.783e-4142.86GTPase HRas-like [Source:NCBI gene;Acc:103023536][more]
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BLAST of Ras-related protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ENSPMAT00000000518.12.517e-5956.41pep scaffold:Pmarinus_7.0:GL479781:11597:21619:-1 ... [more]
ENSPMAT00000005561.12.815e-5956.95pep scaffold:Pmarinus_7.0:GL481089:12431:17765:1 g... [more]
mras2.366e-5648.40muscle RAS oncogene homolog [Source:ZFIN;Acc:ZDB-G... [more]
hrasb1.998e-4044.16HRas proto-oncogene, GTPase b [Source:ZFIN;Acc:ZDB... [more]
ralba2.934e-4038.46v-ral simian leukemia viral oncogene homolog Ba (r... [more]
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BLAST of Ras-related protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 5
Match NameE-valueIdentityDescription
RAS12.955e-4044.37GTPase involved in G-protein signaling in adenylat... [more]
RAS26.250e-4043.35GTP-binding protein; regulates nitrogen starvation... [more]
RSR12.318e-3139.07GTP-binding protein of the Ras superfamily; requir... [more]
SEC41.313e-2235.87Rab family GTPase; essential for vesicle-mediated ... [more]
YPT12.744e-2231.91Rab family GTPase; involved in the ER-to-Golgi ste... [more]
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BLAST of Ras-related protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO391718.044e-4945.40Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO390471.260e-4041.14Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO458273.561e-3944.16Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO329144.952e-3845.78Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO363964.059e-3643.05Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Ras-related protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
si:ch73-116o1.27.459e-6056.28muscle RAS oncogene homolog [Source:NCBI gene;Acc:... [more]
rras22.998e-4944.92RAS related 2 [Source:NCBI gene;Acc:101162668][more]
rras1.887e-4643.58ras-related protein R-Ras [Source:NCBI gene;Acc:10... [more]
hrasb6.200e-4145.45HRas proto-oncogene, GTPase [Source:NCBI gene;Acc:... [more]
hrasb6.200e-4145.45HRas proto-oncogene, GTPase [Source:NCBI gene;Acc:... [more]
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BLAST of Ras-related protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000024796.11.418e-131100.00SMESG000024796.1[more]
SMESG000075044.11.946e-5150.99SMESG000075044.1[more]
SMESG000017314.11.601e-4142.29SMESG000017314.1[more]
SMESG000075225.12.544e-3645.40SMESG000075225.1[more]
SMESG000016219.11.695e-3539.87SMESG000016219.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30028380 ID=SMED30028380|Name=Ras-related protein|organism=Schmidtea mediterranea sexual|type=transcript|length=741bp
AATCTATATAAATCTTATATGGTTATTTGCTCAAGATGCCTAAACTTCCA
AGTGATTTATCAAATATGTCTAAAATGAAAATAGTAGTAATAGGTGATGG
AGGAGTAGGAAAGTCAGCTATTATATTACAATTTATGCAAAAGATATTCG
TCGAAAACCATGACCCGACAATAGAGTCTACGTATTATAAAAATTATGAA
GTCGATGGTGAATGGAGTAATCTTGAAGTTCAAGATACTGCGGGCCAAGA
GGAATTTGCTTCGATGAGAGAATCATACTATCGAGCGGCAAACGGCTTTC
TAATCGTTTTTTCCCTCACAACCCGAGAGAGCTTTGAAATTGTTCGCCGA
TTTTTTCAAAGTGCTCTTCGTTCAAGAGATCGTGACCATTTTCCAATGTT
GCTTGTTGCCAACAAAACTGATTTGGAAATGAACCGAAAAGTCACGACTT
CAGAAATTGAAAGTCTAGCAAAGGAGTTACAAATAGACTATATTGAAACT
AGTGCTAAAAATCCACCAATCAATATCGAAGATGCATTTTCTCAGATTGT
TCGTAAGATCAGATCCCATCAACAGATCAATGATGTGAAGTTAAAATCGC
GGCCCCGGCAAAAGCAGAAATGCTGTTTGATGTAGAAAACAGCTAATAAC
AACTGGACATTGTGTCACTGCTGTTACTGGTGGAGTGGTGGCGTTCACAG
GCACAAAGTTATTGATCCATTATTATTATTATTATTATTAT
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protein sequence of SMED30028380-orf-1

>SMED30028380-orf-1 ID=SMED30028380-orf-1|Name=SMED30028380-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=200bp
MPKLPSDLSNMSKMKIVVIGDGGVGKSAIILQFMQKIFVENHDPTIESTY
YKNYEVDGEWSNLEVQDTAGQEEFASMRESYYRAANGFLIVFSLTTRESF
EIVRRFFQSALRSRDRDHFPMLLVANKTDLEMNRKVTTSEIESLAKELQI
DYIETSAKNPPINIEDAFSQIVRKIRSHQQINDVKLKSRPRQKQKCCLM*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: molecular function
TermDefinition
GO:0003924GTPase activity
GO:0005525GTP binding
GO:0000166nucleotide binding
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000026gut
PLANA:0000034epidermis
PLANA:0000043dorsal ventral margin of the whole animal
PLANA:0000070intestinal phagocyte
Vocabulary: INTERPRO
TermDefinition
IPR005225Small_GTP-bd_dom
IPR027417P-loop_NTPase
IPR001806Small_GTPase
IPR020849Small_GTPase_Ras-type
Vocabulary: biological process
TermDefinition
GO:0007264small GTPase mediated signal transduction
GO:0007165signal transduction
Vocabulary: cellular component
TermDefinition
GO:0016020membrane
GO:0005622intracellular
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
NoneNo IPR availablePRINTSPR00449RASTRNSFRMNGcoord: 122..135
score: 45.34
coord: 59..81
score: 42.08
coord: 19..40
score: 47.07
coord: 42..58
score: 27.47
coord: 158..180
score: 20.52
NoneNo IPR availableSMARTSM00173ras_sub_4coord: 16..183
e-value: 4.1E-82
score: 288.8
NoneNo IPR availableSMARTSM00175rab_sub_5coord: 19..183
e-value: 3.8E-37
score: 139.4
NoneNo IPR availableSMARTSM00174rho_sub_3coord: 21..183
e-value: 2.3E-10
score: 13.6
NoneNo IPR availableGENE3DG3DSA:3.40.50.300coord: 16..204
e-value: 9.1E-59
score: 199.9
NoneNo IPR availablePANTHERPTHR24070:SF268RAS-RELATED PROTEIN M-RAScoord: 10..197
IPR005225Small GTP-binding protein domainTIGRFAMTIGR00231TIGR00231coord: 16..174
e-value: 1.2E-26
score: 91.4
IPR001806Small GTPasePFAMPF00071Rascoord: 20..181
e-value: 1.0E-50
score: 171.5
IPR020849Small GTPase superfamily, Ras-typePANTHERPTHR24070FAMILY NOT NAMEDcoord: 10..197
IPR020849Small GTPase superfamily, Ras-typePROSITEPS51421RAScoord: 14..204
score: 31.832
IPR027417P-loop containing nucleoside triphosphate hydrolaseSUPERFAMILYSSF52540P-loop containing nucleoside triphosphate hydrolasescoord: 18..191