Engulfment and cell motility 3

Overview
NameEngulfment and cell motility 3
Smed IDSMED30028347
Length (bp)2459
Neoblast Clusters

Zeng et. al., 2018




▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 



 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)




Explore this single cell expression dataset with our NB Cluster Shiny App




 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Engulfment and cell motility 3 (SMED30028347) t-SNE clustered cells

Violin plots show distribution of expression levels for Engulfment and cell motility 3 (SMED30028347) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Engulfment and cell motility 3 (SMED30028347) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Engulfment and cell motility 3 (SMED30028347) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017




Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020




SMED30028347

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 9

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
pharynxSMED30028347h1SMcG0008397 Contig1935GPL15192PMID:23079596
Forsthoefel et al., 2012
whole organism asexual adult colorimetric in situ hybridization evidence
gutSMED30028347h1SMcG0008397 Contig1935GPL15192PMID:23079596
Forsthoefel et al., 2012
whole organism asexual adult colorimetric in situ hybridization evidence
intestinal phagocyteSMED30028347h1SMcG0008397 Contig1935GPL15192PMID:23079596
Forsthoefel et al., 2012
FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
Smed sexual biotypeSMED30028347h1SMcG0008397 Contig54712uc_Smed_v2PMID:29674431
Fincher et al., 2018
FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30028347h1SMcG0008397 Contig54712newmark_estsPMID:29674431
Fincher et al., 2018
FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
cephalic gangliaSMED30028347h1SMcG0008397 dd_Smed_v4_3754_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
neoblastSMED30028347h1SMcG0008397 dd_Smed_v4_3754_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymal cellSMED30028347h1SMcG0008397 dd_Smed_v4_3754_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
epidermisSMED30028347h1SMcG0008397 dd_Smed_v4_3754_0_1dd_Smed_v4PMID:28292427
Wurtzel et al., 2017
whole organism asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
BLAST of Engulfment and cell motility 3 vs. Ensembl Human
Match: ELMO2 (engulfment and cell motility 2 [Source:HGNC Symbol;Acc:HGNC:17233])

HSP 1 Score: 114.005 bits (284), Expect = 1.833e-25
Identity = 109/391 (27.88%), Postives = 180/391 (46.04%), Query Frame = 1
Query: 1207 FEKLGFQNPSSPSRDFTE-PPGHLVFSCIKYLINNCDEIY-----HNFAKRVFNNIPLIKIAFSLVKILDRALQLTEIIDENMDGGLYLPILFHTCEIDNDLSKKFFYELFQKCFVVYAQSLIDLKFKVEDL-ELESYFLNQINEVLNCYPTSFHDLSIWLGKVRSENTRKKKLEDQITEWESNQNIQNPVINQLRTELESEYKALINKKRIRQLQERPHAFDLRSAKGVQRY---SLQLDESQSIILAKEESDPNSKVN------KWPISNIKQVLIDKACSHYNQR---KENT----FYFSITMDSRDDARDDPIRTYNFSCNHKKNYAVWIDGLNILMNKPPTSQEFKEDLLNLVRMEMKIRFLFLSKENIHHEAPALPTLPSNYDFC 2310
            ++ LGF N  +P+ DFT+ PPG L    + YL     + Y      N ++   +  P  + A  L K+L   LQ+ E+ +E  +   Y P+ F           + F ELF  C  +  ++  +++   ED  ++      QI   L   P S   L  +  K+RS  +  + L  + +E  S  + Q+P I +LR +++ E   LI ++R+ +L E      + + +  +R+    L L+  + +     + +P  +V       K P+++IK ++  K C H  ++   K+N       FSI  D        P  T NF   +K  Y +WIDGL+ L+ K  +S+  K DL  L+ MEMK+R L L    I    P +P  PS+YDF 
Sbjct:  261 YKMLGFTNHINPAMDFTQTPPGMLALDNMLYLAKVHQDTYIRIVLENSSREDKHECPFGRSAIELTKMLCEILQVGELPNEGRND--YHPMFF--------THDRAFEELFGICIQLLNKTWKEMRATAEDFNKVMQVVREQITRALPSKPNS---LDQFKSKLRSL-SYSEILRLRQSERMSQDDFQSPPIVELREKIQPEILELIKQQRLNRLCEGSSFRKIGNRRRQERFWYCRLALNH-KVLHYGDLDDNPQGEVTFESLQEKIPVADIKAIVTGKDCPHMKEKSALKQNKEVLELAFSILYD--------PDETLNFIAPNKYEYCIWIDGLSALLGKDMSSELTKSDLDTLLSMEMKLRLLDLENIQIPEAPPPIPKEPSSYDFV 628          
BLAST of Engulfment and cell motility 3 vs. Ensembl Human
Match: ELMO2 (engulfment and cell motility 2 [Source:HGNC Symbol;Acc:HGNC:17233])

HSP 1 Score: 114.005 bits (284), Expect = 2.426e-25
Identity = 109/391 (27.88%), Postives = 180/391 (46.04%), Query Frame = 1
Query: 1207 FEKLGFQNPSSPSRDFTE-PPGHLVFSCIKYLINNCDEIY-----HNFAKRVFNNIPLIKIAFSLVKILDRALQLTEIIDENMDGGLYLPILFHTCEIDNDLSKKFFYELFQKCFVVYAQSLIDLKFKVEDL-ELESYFLNQINEVLNCYPTSFHDLSIWLGKVRSENTRKKKLEDQITEWESNQNIQNPVINQLRTELESEYKALINKKRIRQLQERPHAFDLRSAKGVQRY---SLQLDESQSIILAKEESDPNSKVN------KWPISNIKQVLIDKACSHYNQR---KENT----FYFSITMDSRDDARDDPIRTYNFSCNHKKNYAVWIDGLNILMNKPPTSQEFKEDLLNLVRMEMKIRFLFLSKENIHHEAPALPTLPSNYDFC 2310
            ++ LGF N  +P+ DFT+ PPG L    + YL     + Y      N ++   +  P  + A  L K+L   LQ+ E+ +E  +   Y P+ F           + F ELF  C  +  ++  +++   ED  ++      QI   L   P S   L  +  K+RS  +  + L  + +E  S  + Q+P I +LR +++ E   LI ++R+ +L E      + + +  +R+    L L+  + +     + +P  +V       K P+++IK ++  K C H  ++   K+N       FSI  D        P  T NF   +K  Y +WIDGL+ L+ K  +S+  K DL  L+ MEMK+R L L    I    P +P  PS+YDF 
Sbjct:  347 YKMLGFTNHINPAMDFTQTPPGMLALDNMLYLAKVHQDTYIRIVLENSSREDKHECPFGRSAIELTKMLCEILQVGELPNEGRND--YHPMFF--------THDRAFEELFGICIQLLNKTWKEMRATAEDFNKVMQVVREQITRALPSKPNS---LDQFKSKLRSL-SYSEILRLRQSERMSQDDFQSPPIVELREKIQPEILELIKQQRLNRLCEGSSFRKIGNRRRQERFWYCRLALNH-KVLHYGDLDDNPQGEVTFESLQEKIPVADIKAIVTGKDCPHMKEKSALKQNKEVLELAFSILYD--------PDETLNFIAPNKYEYCIWIDGLSALLGKDMSSELTKSDLDTLLSMEMKLRLLDLENIQIPEAPPPIPKEPSSYDFV 714          
BLAST of Engulfment and cell motility 3 vs. Ensembl Human
Match: ELMO2 (engulfment and cell motility 2 [Source:HGNC Symbol;Acc:HGNC:17233])

HSP 1 Score: 114.005 bits (284), Expect = 2.503e-25
Identity = 108/391 (27.62%), Postives = 178/391 (45.52%), Query Frame = 1
Query: 1207 FEKLGFQNPSSPSRDFTE-PPGHLVFSCIKYLINNCDEIY-----HNFAKRVFNNIPLIKIAFSLVKILDRALQLTEIIDENMDGGLYLPILFHTCEIDNDLSKKFFYELFQKCFVVYAQSLIDLKFKVEDL-ELESYFLNQINEVLNCYPTSFHDLSIWLGKVRSENTRKKKLEDQITEWESNQNIQNPVINQLRTELESEYKALINKKRIRQLQERPHAFDLRSAKGVQRY---SLQLDESQSIILAKEESDPNSKVN------KWPISNIKQVLIDKACSHYNQR---KENT----FYFSITMDSRDDARDDPIRTYNFSCNHKKNYAVWIDGLNILMNKPPTSQEFKEDLLNLVRMEMKIRFLFLSKENIHHEAPALPTLPSNYDFC 2310
            ++ LGF N  +P+ DFT+ PPG L    + YL     + Y      N ++   +  P  + A  L K+L   LQ+ E+ +E  +   Y P+ F           + F ELF  C  +  ++  +++   ED  ++      QI   L   P S         K+RS  +  + L  + +E  S  + Q+P I +LR +++ E   LI ++R+ +L E      + + +  +R+    L L+  + +     + +P  +V       K P+++IK ++  K C H  ++   K+N       FSI  D        P  T NF   +K  Y +WIDGL+ L+ K  +S+  K DL  L+ MEMK+R L L    I    P +P  PS+YDF 
Sbjct:  349 YKMLGFTNHINPAMDFTQTPPGMLALDNMLYLAKVHQDTYIRIVLENSSREDKHECPFGRSAIELTKMLCEILQVGELPNEGRND--YHPMFF--------THDRAFEELFGICIQLLNKTWKEMRATAEDFNKVMQVVREQITRALPSKPNSLDQFK---SKLRSL-SYSEILRLRQSERMSQDDFQSPPIVELREKIQPEILELIKQQRLNRLCEGSSFRKIGNRRRQERFWYCRLALNH-KVLHYGDLDDNPQGEVTFESLQEKIPVADIKAIVTGKDCPHMKEKSALKQNKEVLELAFSILYD--------PDETLNFIAPNKYEYCIWIDGLSALLGKDMSSELTKSDLDTLLSMEMKLRLLDLENIQIPEAPPPIPKEPSSYDFV 716          
BLAST of Engulfment and cell motility 3 vs. Ensembl Human
Match: ELMO2 (engulfment and cell motility 2 [Source:HGNC Symbol;Acc:HGNC:17233])

HSP 1 Score: 114.005 bits (284), Expect = 2.503e-25
Identity = 108/391 (27.62%), Postives = 178/391 (45.52%), Query Frame = 1
Query: 1207 FEKLGFQNPSSPSRDFTE-PPGHLVFSCIKYLINNCDEIY-----HNFAKRVFNNIPLIKIAFSLVKILDRALQLTEIIDENMDGGLYLPILFHTCEIDNDLSKKFFYELFQKCFVVYAQSLIDLKFKVEDL-ELESYFLNQINEVLNCYPTSFHDLSIWLGKVRSENTRKKKLEDQITEWESNQNIQNPVINQLRTELESEYKALINKKRIRQLQERPHAFDLRSAKGVQRY---SLQLDESQSIILAKEESDPNSKVN------KWPISNIKQVLIDKACSHYNQR---KENT----FYFSITMDSRDDARDDPIRTYNFSCNHKKNYAVWIDGLNILMNKPPTSQEFKEDLLNLVRMEMKIRFLFLSKENIHHEAPALPTLPSNYDFC 2310
            ++ LGF N  +P+ DFT+ PPG L    + YL     + Y      N ++   +  P  + A  L K+L   LQ+ E+ +E  +   Y P+ F           + F ELF  C  +  ++  +++   ED  ++      QI   L   P S         K+RS  +  + L  + +E  S  + Q+P I +LR +++ E   LI ++R+ +L E      + + +  +R+    L L+  + +     + +P  +V       K P+++IK ++  K C H  ++   K+N       FSI  D        P  T NF   +K  Y +WIDGL+ L+ K  +S+  K DL  L+ MEMK+R L L    I    P +P  PS+YDF 
Sbjct:  349 YKMLGFTNHINPAMDFTQTPPGMLALDNMLYLAKVHQDTYIRIVLENSSREDKHECPFGRSAIELTKMLCEILQVGELPNEGRND--YHPMFF--------THDRAFEELFGICIQLLNKTWKEMRATAEDFNKVMQVVREQITRALPSKPNSLDQFK---SKLRSL-SYSEILRLRQSERMSQDDFQSPPIVELREKIQPEILELIKQQRLNRLCEGSSFRKIGNRRRQERFWYCRLALNH-KVLHYGDLDDNPQGEVTFESLQEKIPVADIKAIVTGKDCPHMKEKSALKQNKEVLELAFSILYD--------PDETLNFIAPNKYEYCIWIDGLSALLGKDMSSELTKSDLDTLLSMEMKLRLLDLENIQIPEAPPPIPKEPSSYDFV 716          
BLAST of Engulfment and cell motility 3 vs. Ensembl Human
Match: ELMO1 (engulfment and cell motility 1 [Source:HGNC Symbol;Acc:HGNC:16286])

HSP 1 Score: 95.9005 bits (237), Expect = 1.097e-19
Identity = 100/394 (25.38%), Postives = 172/394 (43.65%), Query Frame = 1
Query: 1207 FEKLGFQNPSSPSRDFTE-PPGHLVFSCIKYLINNCDEIY-----HNFAKRVFNNIPLIKIAFSLVKILDRALQLTEIIDENMDGGLYLPILFHTCEIDNDLSKKFFYELFQKCFVVYAQSLIDLKFKVEDL-ELESYFLNQINEVLNCYPTSFHDLSIWLGKVRSENTRKKKLEDQITEWESNQNIQNPVINQLRTELESEYKALINKKRIRQLQERPHAFDLRSAKGVQRY-SLQLDESQSIILAKE-ESDPNSKV------NKWPISNIKQVLIDKACSHYNQR---KENT----FYFSITMDSRDDARDDPIRTYNFSCNHKKNYAVWIDGLNILMNKPPTSQEFKEDLLNLVRMEMKIRFLFLSKENIHHEAPALPTLPSNYDF---CN 2313
            ++KLGF N  +P+ DFT+ PPG L    + Y   +  + Y      N ++   +  P  + +  L K+L   L++ E+  E  +        FH     +D S   F E F  C  +  ++  +++   ED  ++      Q+   L   P+S       L  +      K +  +++ +    ++ Q+  I +L+ +++ E   LI ++R+ +L E      L + +   ++   +L  +  ++   + E  P  +V      +K P+++IK V+  K C H  ++   K+N       FSI  DS            NF    K  Y +W DGLN L+ K   S   + DL  L+ ME+K+R L L    I    P +P  PSNYDF   CN
Sbjct:  356 YKKLGFINHVNPAMDFTQTPPGMLALDNMLYFAKHHQDAYIRIVLENSSREDKHECPFGRSSIELTKMLCEILKVGELPSETCND-------FHPMFFTHDRS---FEEFFCICIQLLNKTWKEMRATSEDFNKVMQVVKEQVMRALTTKPSSLDQFKSKLQNLSYTEILKIRQSERMNQ----EDFQSRPILELKEKIQPEILELIKQQRLNRLVEGTCFRKLNARRRQDKFWYCRLSPNHKVLHYGDLEESPQGEVPHDSLQDKLPVADIKAVVTGKDCPHMKEKGALKQNKEVLELAFSILYDSNCQ--------LNFIAPDKHEYCIWTDGLNALLGKDMMSDLTRNDLDTLLSMEIKLRLLDLENIQIPDAPPPIPKEPSNYDFVYDCN 727          
BLAST of Engulfment and cell motility 3 vs. Ensembl Fly
Match: Ced-12 (gene:FBgn0032409 transcript:FBtr0080330)

HSP 1 Score: 97.4413 bits (241), Expect = 1.682e-20
Identity = 107/416 (25.72%), Postives = 181/416 (43.51%), Query Frame = 1
Query: 1117 DTNYDGPKINDLELFKQMLSGNDSDTDFQVFEKLGFQNPSSPSRDFTE-PPGHLVFSCIKYLINNCDEIY-----HNFAKRVFNNIPLIKIAFSLVKILDRALQLTEIIDENMDGGLYLPILFHTCEIDNDLSKKFFYELFQKCFVVYAQSLIDLKFKVEDLELE-SYFLNQINEVLNCYPTSFHDLSIWLGKVRSENTRKKKLEDQITEWESNQNIQNPVINQLRTELESEYKALINKKRIRQLQERPH-AFDLRSAKGVQRY-SLQLDESQSIIL---AKEESDPNSK--VNKWPISNIKQVLIDKACSHYNQ---RKENT-FYFSITMDSRDDARDDPIRTYNFSCNHKKNYAVWIDGLNILMNKPPTSQEFKEDLLNLVRMEMKIRFLFLSKENIHHEAPALPTLPSNYDFC 2310
            D N +    ND  + +   SG  +    Q ++KLGF+   +P++DF E PPG L   C+ Y   N  + Y      N  +   +  P  + +  LVK+L   L++ E   E    G + P+ F             F E F  C +   ++  D++   ED     S    QI   L   P +  D    +  +  +     + +++ ++ E +       I +L+ ++  +   LI ++R+  L E  H A  LR  +   ++   +L  +  +I      E++ P  +    K PIS IKQ+L  K C H  +   RK      FSIT ++ + +      T +F    +  +  W DG+N L+ +P  S++  ED   L+ ME+K+R L     +I  + P +P  P NYDFC
Sbjct:  324 DDNTNALNQNDDHIRRGGGSGAGNVNFSQYYKKLGFKCDINPAQDFIETPPGILALDCMVYFARNYTQQYAKIVRENSCRADEHECPFGRTSIELVKVLCDILRIGEPPAEQ--SGDFQPMFF--------THDSPFEEFFCICVITLNRTWKDMRATAEDFSTTFSVVREQIQRTLKGRPENLDDFRNKIALLTYQQITTLRQQERTSKEECDSTAS--AIVKLKEKISPQILELIKQQRLSFLVEGTHFAKYLRGTRTKDKFWYARLSPNHKVIHYGDCDEKTIPTMEELPKKLPISEIKQLLEGKECPHMKETRIRKSAVNLAFSITFENMEHS------TLDFVAPDESIFNYWTDGINALLGQPMVSKQKNEDFDTLLSMEIKLRLLDTEGVDISKDPPPIPEDPENYDFC 721          
BLAST of Engulfment and cell motility 3 vs. Ensembl Zebrafish
Match: elmo1 (engulfment and cell motility 1 (ced-12 homolog, C. elegans) [Source:ZFIN;Acc:ZDB-GENE-040426-2069])

HSP 1 Score: 102.064 bits (253), Expect = 8.136e-22
Identity = 105/395 (26.58%), Postives = 178/395 (45.06%), Query Frame = 1
Query: 1207 FEKLGFQNPSSPSRDFTE-PPGHLVFSCIKYLINNCDEIY-----HNFAKRVFNNIPLIKIAFSLVKILDRALQLTEIIDENMDGGLYLPILFHTCEIDNDLSKKFFYELFQKCFVVYAQSLIDLKFKVEDL-ELESYFLNQINEVLNCYPTSFHDLSIWLGKVRSEN-TRKKKLEDQITEWESNQNIQNPVINQLRTELESEYKALINKKRIRQLQERPHAFDLRSAKGVQRY-SLQLDESQSIILAKE-ESDPNSKV------NKWPISNIKQVLIDKACSHYNQR---KENT----FYFSITMDSRDDARDDPIRTYNFSCNHKKNYAVWIDGLNILMNKPPTSQEFKEDLLNLVRMEMKIRFLFLSKENIHHEAPALPTLPSNYDF---CN 2313
            ++KLGF N  +P+ DFT+ PPG L    + Y   +  + Y      N ++   +  P  + +  L K+L   L++ E+  EN          FH     +D S   F E F  C  +  ++  +++   ED  ++      QI   L   P S         K R +N +  + L+ + +E  + ++ Q+  I +LR +++ E   LI ++R+ +L E      + S +   ++   +L  +  ++   + E  P  +V      +K P+++IK V+  K C H  ++   K+N       FS+  +S +          NF    K  Y VW DGLN L+ K  +S+  + D+  L+ MEMK+R L L    I    P +P  PSNYDF   CN
Sbjct:  357 YKKLGFINHVNPAVDFTQIPPGMLALDNMLYFARHHQDAYIRIVLENSSREDKHECPFGRSSIELTKMLCEILKVGELPSENCHD-------FHPMFFTHDRS---FEEFFCICIQLLNKTWKEMRATSEDFNKVMQVVKEQITRALTIKPNSLDQF-----KSRLQNLSYTEILKLRQSERMNQEDFQSRPILELREKIQPEIMELIKQQRLNRLCEGTCFRKISSRRRQDKFWYCRLSPNHKVLHYGDLEESPQGEVPHDSLQDKLPVADIKAVVTGKDCPHMKEKGALKQNKEVLELAFSVLYESDE--------YLNFIAPDKHEYCVWTDGLNALLGKEMSSEFTRSDMDTLLNMEMKLRLLDLENIQIPEVPPPIPKEPSNYDFVYDCN 728          
BLAST of Engulfment and cell motility 3 vs. Ensembl Zebrafish
Match: elmo1 (engulfment and cell motility 1 (ced-12 homolog, C. elegans) [Source:ZFIN;Acc:ZDB-GENE-040426-2069])

HSP 1 Score: 102.064 bits (253), Expect = 8.616e-22
Identity = 105/395 (26.58%), Postives = 178/395 (45.06%), Query Frame = 1
Query: 1207 FEKLGFQNPSSPSRDFTE-PPGHLVFSCIKYLINNCDEIY-----HNFAKRVFNNIPLIKIAFSLVKILDRALQLTEIIDENMDGGLYLPILFHTCEIDNDLSKKFFYELFQKCFVVYAQSLIDLKFKVEDL-ELESYFLNQINEVLNCYPTSFHDLSIWLGKVRSEN-TRKKKLEDQITEWESNQNIQNPVINQLRTELESEYKALINKKRIRQLQERPHAFDLRSAKGVQRY-SLQLDESQSIILAKE-ESDPNSKV------NKWPISNIKQVLIDKACSHYNQR---KENT----FYFSITMDSRDDARDDPIRTYNFSCNHKKNYAVWIDGLNILMNKPPTSQEFKEDLLNLVRMEMKIRFLFLSKENIHHEAPALPTLPSNYDF---CN 2313
            ++KLGF N  +P+ DFT+ PPG L    + Y   +  + Y      N ++   +  P  + +  L K+L   L++ E+  EN          FH     +D S   F E F  C  +  ++  +++   ED  ++      QI   L   P S         K R +N +  + L+ + +E  + ++ Q+  I +LR +++ E   LI ++R+ +L E      + S +   ++   +L  +  ++   + E  P  +V      +K P+++IK V+  K C H  ++   K+N       FS+  +S +          NF    K  Y VW DGLN L+ K  +S+  + D+  L+ MEMK+R L L    I    P +P  PSNYDF   CN
Sbjct:  369 YKKLGFINHVNPAVDFTQIPPGMLALDNMLYFARHHQDAYIRIVLENSSREDKHECPFGRSSIELTKMLCEILKVGELPSENCHD-------FHPMFFTHDRS---FEEFFCICIQLLNKTWKEMRATSEDFNKVMQVVKEQITRALTIKPNSLDQF-----KSRLQNLSYTEILKLRQSERMNQEDFQSRPILELREKIQPEIMELIKQQRLNRLCEGTCFRKISSRRRQDKFWYCRLSPNHKVLHYGDLEESPQGEVPHDSLQDKLPVADIKAVVTGKDCPHMKEKGALKQNKEVLELAFSVLYESDE--------YLNFIAPDKHEYCVWTDGLNALLGKEMSSEFTRSDMDTLLNMEMKLRLLDLENIQIPEVPPPIPKEPSNYDFVYDCN 740          
BLAST of Engulfment and cell motility 3 vs. Ensembl Zebrafish
Match: elmo1 (engulfment and cell motility 1 (ced-12 homolog, C. elegans) [Source:ZFIN;Acc:ZDB-GENE-040426-2069])

HSP 1 Score: 102.064 bits (253), Expect = 9.724e-22
Identity = 105/395 (26.58%), Postives = 178/395 (45.06%), Query Frame = 1
Query: 1207 FEKLGFQNPSSPSRDFTE-PPGHLVFSCIKYLINNCDEIY-----HNFAKRVFNNIPLIKIAFSLVKILDRALQLTEIIDENMDGGLYLPILFHTCEIDNDLSKKFFYELFQKCFVVYAQSLIDLKFKVEDL-ELESYFLNQINEVLNCYPTSFHDLSIWLGKVRSEN-TRKKKLEDQITEWESNQNIQNPVINQLRTELESEYKALINKKRIRQLQERPHAFDLRSAKGVQRY-SLQLDESQSIILAKE-ESDPNSKV------NKWPISNIKQVLIDKACSHYNQR---KENT----FYFSITMDSRDDARDDPIRTYNFSCNHKKNYAVWIDGLNILMNKPPTSQEFKEDLLNLVRMEMKIRFLFLSKENIHHEAPALPTLPSNYDF---CN 2313
            ++KLGF N  +P+ DFT+ PPG L    + Y   +  + Y      N ++   +  P  + +  L K+L   L++ E+  EN          FH     +D S   F E F  C  +  ++  +++   ED  ++      QI   L   P S         K R +N +  + L+ + +E  + ++ Q+  I +LR +++ E   LI ++R+ +L E      + S +   ++   +L  +  ++   + E  P  +V      +K P+++IK V+  K C H  ++   K+N       FS+  +S +          NF    K  Y VW DGLN L+ K  +S+  + D+  L+ MEMK+R L L    I    P +P  PSNYDF   CN
Sbjct:  355 YKKLGFINHVNPAVDFTQIPPGMLALDNMLYFARHHQDAYIRIVLENSSREDKHECPFGRSSIELTKMLCEILKVGELPSENCHD-------FHPMFFTHDRS---FEEFFCICIQLLNKTWKEMRATSEDFNKVMQVVKEQITRALTIKPNSLDQF-----KSRLQNLSYTEILKLRQSERMNQEDFQSRPILELREKIQPEIMELIKQQRLNRLCEGTCFRKISSRRRQDKFWYCRLSPNHKVLHYGDLEESPQGEVPHDSLQDKLPVADIKAVVTGKDCPHMKEKGALKQNKEVLELAFSVLYESDE--------YLNFIAPDKHEYCVWTDGLNALLGKEMSSEFTRSDMDTLLNMEMKLRLLDLENIQIPEVPPPIPKEPSNYDFVYDCN 726          
BLAST of Engulfment and cell motility 3 vs. Ensembl Zebrafish
Match: elmo3 (engulfment and cell motility 3 [Source:ZFIN;Acc:ZDB-GENE-050309-39])

HSP 1 Score: 95.1301 bits (235), Expect = 1.149e-19
Identity = 100/391 (25.58%), Postives = 173/391 (44.25%), Query Frame = 1
Query: 1207 FEKLGFQNPSSPSRDFTE-PPGHLVFSCIKYLINNCDEIYHNF-----AKRVFNNIPLIKIAFSLVKILDRALQLTEIIDENMDGGLYLPILFHTCEIDNDLSKKFFYELFQKCFVVYAQSLIDLKFKVEDLE-LESYFLNQINEVLNCYPTSFHDLSIWLGKVRSENTRKKKLEDQITEWESNQNIQNPVINQLRTELESEYKALINKKRIRQLQERPHAFDLRSAKGVQR----YSLQLDESQSII----LAKEESDPNSKV--NKWPISNIKQVLIDKACSHYNQRKENT------FYFSITMDSRDDARDDPIRTYNFSCNHKKNYAVWIDGLNILMNKPPTSQEFKEDLLNLVRMEMKIRFLFLSKENIHHEAPALPTLPSNYDFC 2310
            F+KLGF N S+P +D +  PPG L    + Y  +   + Y  F     ++   +  P  + +  L  IL   L++ E   E   G  Y PI F           +   ELF  C  +  ++  +++   ED + +      QI   L   PTS   L ++  KV + N  +     Q       + +  PV+ +L+  L+ E   LI ++R+ +L    H    R     +R    +  +L  +  ++    + +E   P+ +   +K P+++IK V+  K C H  + K           FSIT D  +        + NF  + + ++ +W DGL++L+ K  +S+  + +L  L+ ME+K+R L L    I   AP +P  PSN++FC
Sbjct:  341 FKKLGFSNNSNPGQDLSRCPPGLLALDTMAYFASRYPDAYSRFVLENSSREDKHECPFARSSIQLTLILCEILRIGEPPSET--GSDYHPIFFA--------QDRLLEELFCICIQLLNKTWKEMRATQEDFDKVMQVVREQITRTLASKPTS---LELFKNKVNALNYSEILKLRQTERLHQEETLAPPVL-ELKERLKPELLELIRQQRLNRL---CHGTLFRKMSSRRRQDKLWYCRLSPNHKVLHYGDVEEETEMPSIEALQDKIPVADIKNVVTGKDCPHMKENKGKQTKEVLDLAFSITYDVEE-------YSLNFIASSRTDFCLWTDGLSVLLGKEMSSESMRSELEILLSMEIKLRLLDLENVPIPDAAPPIPKPPSNFNFC 707          
BLAST of Engulfment and cell motility 3 vs. Ensembl Zebrafish
Match: elmo2 (engulfment and cell motility 2 [Source:ZFIN;Acc:ZDB-GENE-140106-84])

HSP 1 Score: 88.5817 bits (218), Expect = 1.504e-18
Identity = 89/348 (25.57%), Postives = 155/348 (44.54%), Query Frame = 1
Query: 1318 IYHNFAKRVFNNIPLIKIAFSLVKILDRALQLTEIIDENMDGGLYLPILFHTCEIDNDLSKKFFYELFQKCFVVYAQSLIDLKFKVEDL-ELESYFLNQINEVLNCYPTSFHDLSIWLGKVR-SENTRKKKLEDQITEWESNQNIQNPVINQLRTELESEYKALINKKRIRQLQERPHAFDLRSAKGVQRY---SLQLDESQSIILAKEESDPNSKV------NKWPISNIKQVLIDKACSHYNQR---KENT----FYFSITMDSRDDARDDPIRTYNFSCNHKKNYAVWIDGLNILMNKPPTSQEFKEDLLNLVRMEMKIRFLFLSKENIHHEAPALPTLPSNYDF 2307
            +  N ++   +  P  + A  L ++L   LQ+ E+ +E  +   + P+ F          ++ + E F  C  +  ++  +++   ED  ++ +    QI   L   P S   L + L  +  SE  R ++     +E  S  + Q+P I +LR  ++ E   LI ++R+ +L E      L + +  +++    L L+  + +     E  P  +V      +K  +S+IK VL  K C H  ++   K+N       FSI  D        P  + NF   +K  Y +W DGL+ L+ K  +S   + DL  L+ MEMK+R L L    I    P +P  PS+Y+F
Sbjct:    2 VLENSSREDKHECPFARCAIELTRVLCDILQVGELPNEGCND--FHPMFFT--------HERAWEEFFCVCIQLLNKTWKEMRATAEDFNKVMTVVREQITRALALKPASLDQLRLKLRSLSYSEILRLRQ-----SERMSQDDFQSPPIIELRERIQPEILELIKQQRLSRLCEGSCFRKLGNRRRQEKFWFCRLSLNH-KLLHYGDLEESPQGEVPLELLTDKIAVSDIKAVLTGKDCPHMKEKSALKQNKEVLELAFSILYD--------PDESLNFVAPNKYEYCIWTDGLSALLGKDLSSDLTRSDLDTLMSMEMKLRLLDLENITIPEAPPPVPKEPSSYNF 325          
BLAST of Engulfment and cell motility 3 vs. Ensembl Xenopus
Match: elmo2 (engulfment and cell motility 2 [Source:NCBI gene;Acc:493485])

HSP 1 Score: 105.145 bits (261), Expect = 1.226e-22
Identity = 112/411 (27.25%), Postives = 177/411 (43.07%), Query Frame = 1
Query: 1171 LSGNDSDTDFQVFEK----LGFQNPSSPSRDFTE-PPGHLVFSCIKYLINNCDEIY-----HNFAKRVFNNIPLIKIAFSLVKILDRALQLTEIIDENMDGGLYLPILFHTCEIDNDLSKKFFYELFQKCFVVYAQSLIDLKFKVEDL-ELESYFLNQINEVLNCYPTSFHDLSIWLGKVRSENTRKKKLEDQITEWESNQNIQNPVINQLRTELESEYKALINKKRI--------------RQLQERPHAFDLRSAKGVQRYSLQLDESQSIILAKEESDPNSKVNKWPISNIKQVLIDKACSHYNQR---KENT----FYFSITMDSRDDARDDPIRTYNFSCNHKKNYAVWIDGLNILMNKPPTSQEFKEDLLNLVRMEMKIRFLFLSKENIHHEAPALPTLPSNYDF 2307
            +SG  ++    ++ K    LGF N  +P+ DF + PPG L    + YL  +  + Y      N ++   +  P  + A  L K+L   LQ+ E+ +E  +   Y P+ F          ++ F E F  C  +  ++  +++   ED  ++      QI   L   P S   L     K+RS  +  + L  + +E  S  + Q+  I +LR +++ E   LI ++R+              R+ QER     L     V  Y    D  Q       E    S   K P+S+IK V+  K C H  ++   K+N       FSI  D        P  T NF   +K  Y +WIDG+N L+ +  +S+  + D+  L+ MEMK+R L L    I    P +P  PS+YDF
Sbjct:  269 VSGGGTEKRKAMYSKDYKMLGFSNHVNPAMDFLQTPPGMLALDNMLYLAKHHQDTYVRIVLENSSREDKHECPFGRSAIELTKMLCDILQVGELPNEGRND--YHPMFF--------THERSFEEFFCICIQLLNKTWKEMRATAEDFNKVMQVVREQITRALASKPNSLEQLK---NKLRSL-SYTEILRLRQSERLSQDDFQSKPIVELREKIQPEILELIKQQRLNRLCEGSSFRKTGNRRRQERFWFCRLALNHKVLHYGDLEDNVQG------EVPYESLQEKIPVSDIKAVVTGKDCPHMKEKSALKQNKEVLELAFSILYD--------PDETLNFIAPNKYEYCIWIDGVNALLGREMSSELARSDMDTLLSMEMKLRLLDLENIQIPEVPPPIPKEPSSYDF 651          
BLAST of Engulfment and cell motility 3 vs. Ensembl Xenopus
Match: elmo2 (engulfment and cell motility 2 [Source:NCBI gene;Acc:493485])

HSP 1 Score: 105.145 bits (261), Expect = 1.475e-22
Identity = 112/411 (27.25%), Postives = 177/411 (43.07%), Query Frame = 1
Query: 1171 LSGNDSDTDFQVFEK----LGFQNPSSPSRDFTE-PPGHLVFSCIKYLINNCDEIY-----HNFAKRVFNNIPLIKIAFSLVKILDRALQLTEIIDENMDGGLYLPILFHTCEIDNDLSKKFFYELFQKCFVVYAQSLIDLKFKVEDL-ELESYFLNQINEVLNCYPTSFHDLSIWLGKVRSENTRKKKLEDQITEWESNQNIQNPVINQLRTELESEYKALINKKRI--------------RQLQERPHAFDLRSAKGVQRYSLQLDESQSIILAKEESDPNSKVNKWPISNIKQVLIDKACSHYNQR---KENT----FYFSITMDSRDDARDDPIRTYNFSCNHKKNYAVWIDGLNILMNKPPTSQEFKEDLLNLVRMEMKIRFLFLSKENIHHEAPALPTLPSNYDF 2307
            +SG  ++    ++ K    LGF N  +P+ DF + PPG L    + YL  +  + Y      N ++   +  P  + A  L K+L   LQ+ E+ +E  +   Y P+ F          ++ F E F  C  +  ++  +++   ED  ++      QI   L   P S   L     K+RS  +  + L  + +E  S  + Q+  I +LR +++ E   LI ++R+              R+ QER     L     V  Y    D  Q       E    S   K P+S+IK V+  K C H  ++   K+N       FSI  D        P  T NF   +K  Y +WIDG+N L+ +  +S+  + D+  L+ MEMK+R L L    I    P +P  PS+YDF
Sbjct:  331 VSGGGTEKRKAMYSKDYKMLGFSNHVNPAMDFLQTPPGMLALDNMLYLAKHHQDTYVRIVLENSSREDKHECPFGRSAIELTKMLCDILQVGELPNEGRND--YHPMFF--------THERSFEEFFCICIQLLNKTWKEMRATAEDFNKVMQVVREQITRALASKPNSLEQLK---NKLRSL-SYTEILRLRQSERLSQDDFQSKPIVELREKIQPEILELIKQQRLNRLCEGSSFRKTGNRRRQERFWFCRLALNHKVLHYGDLEDNVQG------EVPYESLQEKIPVSDIKAVVTGKDCPHMKEKSALKQNKEVLELAFSILYD--------PDETLNFIAPNKYEYCIWIDGVNALLGREMSSELARSDMDTLLSMEMKLRLLDLENIQIPEVPPPIPKEPSSYDF 713          
BLAST of Engulfment and cell motility 3 vs. Ensembl Xenopus
Match: elmo2 (engulfment and cell motility 2 [Source:NCBI gene;Acc:493485])

HSP 1 Score: 105.145 bits (261), Expect = 1.516e-22
Identity = 112/411 (27.25%), Postives = 177/411 (43.07%), Query Frame = 1
Query: 1171 LSGNDSDTDFQVFEK----LGFQNPSSPSRDFTE-PPGHLVFSCIKYLINNCDEIY-----HNFAKRVFNNIPLIKIAFSLVKILDRALQLTEIIDENMDGGLYLPILFHTCEIDNDLSKKFFYELFQKCFVVYAQSLIDLKFKVEDL-ELESYFLNQINEVLNCYPTSFHDLSIWLGKVRSENTRKKKLEDQITEWESNQNIQNPVINQLRTELESEYKALINKKRI--------------RQLQERPHAFDLRSAKGVQRYSLQLDESQSIILAKEESDPNSKVNKWPISNIKQVLIDKACSHYNQR---KENT----FYFSITMDSRDDARDDPIRTYNFSCNHKKNYAVWIDGLNILMNKPPTSQEFKEDLLNLVRMEMKIRFLFLSKENIHHEAPALPTLPSNYDF 2307
            +SG  ++    ++ K    LGF N  +P+ DF + PPG L    + YL  +  + Y      N ++   +  P  + A  L K+L   LQ+ E+ +E  +   Y P+ F          ++ F E F  C  +  ++  +++   ED  ++      QI   L   P S   L     K+RS  +  + L  + +E  S  + Q+  I +LR +++ E   LI ++R+              R+ QER     L     V  Y    D  Q       E    S   K P+S+IK V+  K C H  ++   K+N       FSI  D        P  T NF   +K  Y +WIDG+N L+ +  +S+  + D+  L+ MEMK+R L L    I    P +P  PS+YDF
Sbjct:  344 VSGGGTEKRKAMYSKDYKMLGFSNHVNPAMDFLQTPPGMLALDNMLYLAKHHQDTYVRIVLENSSREDKHECPFGRSAIELTKMLCDILQVGELPNEGRND--YHPMFF--------THERSFEEFFCICIQLLNKTWKEMRATAEDFNKVMQVVREQITRALASKPNSLEQLK---NKLRSL-SYTEILRLRQSERLSQDDFQSKPIVELREKIQPEILELIKQQRLNRLCEGSSFRKTGNRRRQERFWFCRLALNHKVLHYGDLEDNVQG------EVPYESLQEKIPVSDIKAVVTGKDCPHMKEKSALKQNKEVLELAFSILYD--------PDETLNFIAPNKYEYCIWIDGVNALLGREMSSELARSDMDTLLSMEMKLRLLDLENIQIPEVPPPIPKEPSSYDF 726          
BLAST of Engulfment and cell motility 3 vs. Ensembl Xenopus
Match: elmo2 (engulfment and cell motility 2 [Source:NCBI gene;Acc:493485])

HSP 1 Score: 104.76 bits (260), Expect = 1.643e-22
Identity = 112/412 (27.18%), Postives = 177/412 (42.96%), Query Frame = 1
Query: 1171 LSGNDSDTDFQVFEK----LGFQNPSSPSRDFTE-PPGHLVFSCIKYLINNCDEIY-----HNFAKRVFNNIPLIKIAFSLVKILDRALQLTEIIDENMDGGLYLPILFHTCEIDNDLSKKFFYELFQKCFVVYAQSLIDLKFKVEDL-ELESYFLNQINEVLNCYPTSFHDLSIWLGKVRSENTRKKKLEDQITEWESNQNIQNPVINQLRTELESEYKALINKKRI--------------RQLQERPHAFDLRSAKGVQRYSLQLDESQSIILAKEESDPNSKVNKWPISNIKQVLIDKACSHYNQR---KENT----FYFSITMDSRDDARDDPIRTYNFSCNHKKNYAVWIDGLNILMNKPPTSQEFKEDLLNLVRMEMKIRFLFLSKENIHHEAPALPTLPSNYDFC 2310
            +SG  ++    ++ K    LGF N  +P+ DF + PPG L    + YL  +  + Y      N ++   +  P  + A  L K+L   LQ+ E+ +E  +   Y P+ F          ++ F E F  C  +  ++  +++   ED  ++      QI   L   P S   L     K+RS  +  + L  + +E  S  + Q+  I +LR +++ E   LI ++R+              R+ QER     L     V  Y    D  Q       E    S   K P+S+IK V+  K C H  ++   K+N       FSI  D        P  T NF   +K  Y +WIDG+N L+ +  +S+  + D+  L+ MEMK+R L L    I    P +P  PS+YDF 
Sbjct:  345 VSGGGTEKRKAMYSKDYKMLGFSNHVNPAMDFLQTPPGMLALDNMLYLAKHHQDTYVRIVLENSSREDKHECPFGRSAIELTKMLCDILQVGELPNEGRND--YHPMFF--------THERSFEEFFCICIQLLNKTWKEMRATAEDFNKVMQVVREQITRALASKPNSLEQLK---NKLRSL-SYTEILRLRQSERLSQDDFQSKPIVELREKIQPEILELIKQQRLNRLCEGSSFRKTGNRRRQERFWFCRLALNHKVLHYGDLEDNVQG------EVPYESLQEKIPVSDIKAVVTGKDCPHMKEKSALKQNKEVLELAFSILYD--------PDETLNFIAPNKYEYCIWIDGVNALLGREMSSELARSDMDTLLSMEMKLRLLDLENIQIPEVPPPIPKEPSSYDFV 728          
BLAST of Engulfment and cell motility 3 vs. Ensembl Xenopus
Match: ELMO1 (engulfment and cell motility 1 [Source:NCBI gene;Acc:100380096])

HSP 1 Score: 97.0561 bits (240), Expect = 3.663e-20
Identity = 103/395 (26.08%), Postives = 175/395 (44.30%), Query Frame = 1
Query: 1207 FEKLGFQNPSSPSRDFTE-PPGHLVFSCIKYLINNCDEIY-----HNFAKRVFNNIPLIKIAFSLVKILDRALQLTEIIDENMDGGLYLPILFHTCEIDNDLSKKFFYELFQKCFVVYAQSLIDLKFKVEDL-ELESYFLNQINEVLNCYPTSFHDLSIWLGKVRSEN-TRKKKLEDQITEWESNQNIQNPVINQLRTELESEYKALINKKRIRQLQERPHAFDLRSAKGVQRY-SLQLDESQSIILAKE-ESDPNSKV------NKWPISNIKQVLIDKACSHYNQR---KENT----FYFSITMDSRDDARDDPIRTYNFSCNHKKNYAVWIDGLNILMNKPPTSQEFKEDLLNLVRMEMKIRFLFLSKENIHHEAPALPTLPSNYDF---CN 2313
            ++KLGF N  +P+ DFT  PPG L    + Y   +  + Y      N ++   +  P  + +  L K+L   L++ E+  E  +        FH     +D S   F E F  C  +  ++  +++   ED  ++      QI   L   P+S         K R +N +  + L+ + +E  + ++ Q+  I +L+ +++ E   LI ++R+ +L E      L S +   ++   +L  +  ++   + E  P  +V      +K P+++IK ++  K C H  ++   K+N       FSI  DS            NF    K  Y +W DGLN L+ K   S   + D+  L+ ME+K+R L L    I    P +P  PSNYDF   CN
Sbjct:  248 YKKLGFTNNVNPALDFTHTPPGMLALDNMLYFAKHHQDAYIRIVLENSSREDKHECPFGRSSIELTKMLCEILKVGELPSETCND-------FHPMFFTHDRS---FEEFFCICIQLLNKTWKEMRATSEDFNKVMQVVKEQIMRALTNKPSSLDQF-----KCRLQNLSYTEILKIRQSERMNQEDFQSRPILELKDKIQPEIIELIKQQRLNRLVEGTCFRKLNSRRRQDKFWYCRLSPNHKVLHYGDLEESPQGEVPHDSLQDKLPVADIKAIVTGKDCPHMKEKGALKQNKEVLELAFSIMYDSN--------CQLNFIAPDKHEYCIWTDGLNALLGKDMISDLTRNDMDTLLSMELKLRLLDLENIQIPDAPPPIPKEPSNYDFVYDCN 619          
BLAST of Engulfment and cell motility 3 vs. Ensembl Mouse
Match: Elmo2 (engulfment and cell motility 2 [Source:MGI Symbol;Acc:MGI:2153045])

HSP 1 Score: 113.62 bits (283), Expect = 2.253e-25
Identity = 109/390 (27.95%), Postives = 180/390 (46.15%), Query Frame = 1
Query: 1207 FEKLGFQNPSSPSRDFTE-PPGHLVFSCIKYLINNCDEIY-----HNFAKRVFNNIPLIKIAFSLVKILDRALQLTEIIDENMDGGLYLPILFHTCEIDNDLSKKFFYELFQKCFVVYAQSLIDLKFKVEDL-ELESYFLNQINEVLNCYPTSFHDLSIWLGKVRSENTRKKKLEDQITEWESNQNIQNPVINQLRTELESEYKALINKKRIRQLQERPHAFDLRSAKGVQRY-SLQLDESQSIILAKEESD-PNSKVN------KWPISNIKQVLIDKACSHYNQR---KENT----FYFSITMDSRDDARDDPIRTYNFSCNHKKNYAVWIDGLNILMNKPPTSQEFKEDLLNLVRMEMKIRFLFLSKENIHHEAPALPTLPSNYDFC 2310
            ++ LGF N  +P+ DFT+ PPG L    + YL     + Y      N ++   +  P  + A  L K+L   LQ+ E+ +E  +   Y P+ F           + F ELF  C  +  ++  +++   ED  ++      QI   L   P S   L  +  K+RS  +  + L  + +E  S  + Q+P I +LR +++ E   LI ++R+ +L E      + + +  +R+   +L  +  ++   +  D P  +V       K P+++IK ++  K C H  ++   K+N       FSI  D        P  T NF   +K  Y +WIDGL+ L+ K  +S+  K DL  L+ MEMK+R L L    I    P +P  PS+YDF 
Sbjct:  349 YKMLGFTNHINPALDFTQTPPGMLALDNMLYLAKVHQDTYIRIVLENSSREDKHECPFGRSAIELTKMLCEILQVGELPNEGRND--YHPMFF--------THDRAFEELFGICIQLLNKTWKEMRATAEDFNKVMQVVREQITRALPSKPNS---LDQFKSKLRSL-SYSEILRLRQSERMSQDDFQSPPIVELREKIQPEILELIKQQRLNRLCEGSSFRKIGNRRRQERFWHCRLALNHKVLHYGDLDDNPQGEVTFESLQEKIPVADIKAIVTGKDCPHMKEKSALKQNKEVLELAFSILYD--------PDETLNFIAPNKYEYCIWIDGLSALLGKDMSSELTKSDLDTLLSMEMKLRLLDLENIQIPEAPPPVPKEPSSYDFV 716          
BLAST of Engulfment and cell motility 3 vs. Ensembl Mouse
Match: Elmo2 (engulfment and cell motility 2 [Source:MGI Symbol;Acc:MGI:2153045])

HSP 1 Score: 113.62 bits (283), Expect = 2.253e-25
Identity = 109/390 (27.95%), Postives = 180/390 (46.15%), Query Frame = 1
Query: 1207 FEKLGFQNPSSPSRDFTE-PPGHLVFSCIKYLINNCDEIY-----HNFAKRVFNNIPLIKIAFSLVKILDRALQLTEIIDENMDGGLYLPILFHTCEIDNDLSKKFFYELFQKCFVVYAQSLIDLKFKVEDL-ELESYFLNQINEVLNCYPTSFHDLSIWLGKVRSENTRKKKLEDQITEWESNQNIQNPVINQLRTELESEYKALINKKRIRQLQERPHAFDLRSAKGVQRY-SLQLDESQSIILAKEESD-PNSKVN------KWPISNIKQVLIDKACSHYNQR---KENT----FYFSITMDSRDDARDDPIRTYNFSCNHKKNYAVWIDGLNILMNKPPTSQEFKEDLLNLVRMEMKIRFLFLSKENIHHEAPALPTLPSNYDFC 2310
            ++ LGF N  +P+ DFT+ PPG L    + YL     + Y      N ++   +  P  + A  L K+L   LQ+ E+ +E  +   Y P+ F           + F ELF  C  +  ++  +++   ED  ++      QI   L   P S   L  +  K+RS  +  + L  + +E  S  + Q+P I +LR +++ E   LI ++R+ +L E      + + +  +R+   +L  +  ++   +  D P  +V       K P+++IK ++  K C H  ++   K+N       FSI  D        P  T NF   +K  Y +WIDGL+ L+ K  +S+  K DL  L+ MEMK+R L L    I    P +P  PS+YDF 
Sbjct:  349 YKMLGFTNHINPALDFTQTPPGMLALDNMLYLAKVHQDTYIRIVLENSSREDKHECPFGRSAIELTKMLCEILQVGELPNEGRND--YHPMFF--------THDRAFEELFGICIQLLNKTWKEMRATAEDFNKVMQVVREQITRALPSKPNS---LDQFKSKLRSL-SYSEILRLRQSERMSQDDFQSPPIVELREKIQPEILELIKQQRLNRLCEGSSFRKIGNRRRQERFWHCRLALNHKVLHYGDLDDNPQGEVTFESLQEKIPVADIKAIVTGKDCPHMKEKSALKQNKEVLELAFSILYD--------PDETLNFIAPNKYEYCIWIDGLSALLGKDMSSELTKSDLDTLLSMEMKLRLLDLENIQIPEAPPPVPKEPSSYDFV 716          
BLAST of Engulfment and cell motility 3 vs. Ensembl Mouse
Match: Elmo2 (engulfment and cell motility 2 [Source:MGI Symbol;Acc:MGI:2153045])

HSP 1 Score: 113.62 bits (283), Expect = 2.283e-25
Identity = 109/390 (27.95%), Postives = 180/390 (46.15%), Query Frame = 1
Query: 1207 FEKLGFQNPSSPSRDFTE-PPGHLVFSCIKYLINNCDEIY-----HNFAKRVFNNIPLIKIAFSLVKILDRALQLTEIIDENMDGGLYLPILFHTCEIDNDLSKKFFYELFQKCFVVYAQSLIDLKFKVEDL-ELESYFLNQINEVLNCYPTSFHDLSIWLGKVRSENTRKKKLEDQITEWESNQNIQNPVINQLRTELESEYKALINKKRIRQLQERPHAFDLRSAKGVQRY-SLQLDESQSIILAKEESD-PNSKVN------KWPISNIKQVLIDKACSHYNQR---KENT----FYFSITMDSRDDARDDPIRTYNFSCNHKKNYAVWIDGLNILMNKPPTSQEFKEDLLNLVRMEMKIRFLFLSKENIHHEAPALPTLPSNYDFC 2310
            ++ LGF N  +P+ DFT+ PPG L    + YL     + Y      N ++   +  P  + A  L K+L   LQ+ E+ +E  +   Y P+ F           + F ELF  C  +  ++  +++   ED  ++      QI   L   P S   L  +  K+RS  +  + L  + +E  S  + Q+P I +LR +++ E   LI ++R+ +L E      + + +  +R+   +L  +  ++   +  D P  +V       K P+++IK ++  K C H  ++   K+N       FSI  D        P  T NF   +K  Y +WIDGL+ L+ K  +S+  K DL  L+ MEMK+R L L    I    P +P  PS+YDF 
Sbjct:  361 YKMLGFTNHINPALDFTQTPPGMLALDNMLYLAKVHQDTYIRIVLENSSREDKHECPFGRSAIELTKMLCEILQVGELPNEGRND--YHPMFF--------THDRAFEELFGICIQLLNKTWKEMRATAEDFNKVMQVVREQITRALPSKPNS---LDQFKSKLRSL-SYSEILRLRQSERMSQDDFQSPPIVELREKIQPEILELIKQQRLNRLCEGSSFRKIGNRRRQERFWHCRLALNHKVLHYGDLDDNPQGEVTFESLQEKIPVADIKAIVTGKDCPHMKEKSALKQNKEVLELAFSILYD--------PDETLNFIAPNKYEYCIWIDGLSALLGKDMSSELTKSDLDTLLSMEMKLRLLDLENIQIPEAPPPVPKEPSSYDFV 728          
BLAST of Engulfment and cell motility 3 vs. Ensembl Mouse
Match: Elmo1 (engulfment and cell motility 1 [Source:MGI Symbol;Acc:MGI:2153044])

HSP 1 Score: 95.9005 bits (237), Expect = 6.968e-20
Identity = 100/394 (25.38%), Postives = 172/394 (43.65%), Query Frame = 1
Query: 1207 FEKLGFQNPSSPSRDFTE-PPGHLVFSCIKYLINNCDEIY-----HNFAKRVFNNIPLIKIAFSLVKILDRALQLTEIIDENMDGGLYLPILFHTCEIDNDLSKKFFYELFQKCFVVYAQSLIDLKFKVEDL-ELESYFLNQINEVLNCYPTSFHDLSIWLGKVRSENTRKKKLEDQITEWESNQNIQNPVINQLRTELESEYKALINKKRIRQLQERPHAFDLRSAKGVQRY-SLQLDESQSIILAKE-ESDPNSKV------NKWPISNIKQVLIDKACSHYNQR---KENT----FYFSITMDSRDDARDDPIRTYNFSCNHKKNYAVWIDGLNILMNKPPTSQEFKEDLLNLVRMEMKIRFLFLSKENIHHEAPALPTLPSNYDF---CN 2313
            ++KLGF N  +P+ DFT+ PPG L    + Y   +  + Y      N ++   +  P  + +  L K+L   L++ E+  E  +        FH     +D S   F E F  C  +  ++  +++   ED  ++      Q+   L   P+S       L  +      K +  +++ +    ++ Q+  I +L+ +++ E   LI ++R+ +L E      L + +   ++   +L  +  ++   + E  P  +V      +K P+++IK V+  K C H  ++   K+N       FSI  DS            NF    K  Y +W DGLN L+ K   S   + DL  L+ ME+K+R L L    I    P +P  PSNYDF   CN
Sbjct:  356 YKKLGFINHVNPAMDFTQTPPGMLALDNMLYFAKHHQDAYIRIVLENSSREDKHECPFGRSSIELTKMLCEILKVGELPSETCND-------FHPMFFTHDRS---FEEFFCICIQLLNKTWKEMRATSEDFNKVMQVVKEQVMRALTTKPSSLDQFKSKLQNLSYTEILKIRQSERMNQ----EDFQSRPILELKEKIQPEILELIKQQRLNRLVEGTCFRKLNARRRQDKFWYCRLSPNHKVLHYGDLEESPQGEVPHDSLQDKLPVADIKAVVTGKDCPHMKEKGALKQNKEVLELAFSILYDSNCQ--------LNFIAPDKHEYCIWTDGLNALLGKDMMSDLTRNDLDTLLSMEIKLRLLDLENIQIPDAPPPIPKEPSNYDFVYDCN 727          
BLAST of Engulfment and cell motility 3 vs. Ensembl Mouse
Match: Elmo2 (engulfment and cell motility 2 [Source:MGI Symbol;Acc:MGI:2153045])

HSP 1 Score: 83.1889 bits (204), Expect = 6.412e-17
Identity = 80/281 (28.47%), Postives = 132/281 (46.98%), Query Frame = 1
Query: 1501 KFFYELFQKCFVVYAQSLIDLKFKVEDL-ELESYFLNQINEVLNCYPTSFHDLSIWLGKVRSENTRKKKLEDQITEWESNQNIQNPVINQLRTELESEYKALINKKRIRQLQERPHAFDLRSAKGVQRY-SLQLDESQSIILAKEESD-PNSKVNKWPIS--NIKQVLIDKACSHYNQR---KENT----FYFSITMDSRDDARDDPIRTYNFSCNHKKNYAVWIDGLNILMNKPPTSQEFKEDLLNLVRMEMKIRFLFLSKENIHHEAPALPTLPSNYDF 2307
            + F ELF  C  +  ++  +++   ED  ++      QI   L   P S   L  +  K+RS  +  + L  + +E  S  + Q+P I +LR +++ E   LI ++R+ +L E      + + +  +R+   +L  +  ++   +  D P  +V    +   NIK ++  K C H  ++   K+N       FSI  D        P  T NF   +K  Y +WIDGL+ L+ K  +S+  K DL  L+ MEMK+R L L    I    P +P  PS+YDF
Sbjct:   17 RAFEELFGICIQLLNKTWKEMRATAEDFNKVMQVVREQITRALPSKPNS---LDQFKSKLRSL-SYSEILRLRQSERMSQDDFQSPPIVELREKIQPEILELIKQQRLNRLCEGSSFRKIGNRRRQERFWHCRLALNHKVLHYGDLDDNPQGEVTFESLQEKNIKAIVTGKDCPHMKEKSALKQNKEVLELAFSILYD--------PDETLNFIAPNKYEYCIWIDGLSALLGKDMSSELTKSDLDTLLSMEMKLRLLDLENIQIPEAPPPVPKEPSSYDF 285          
BLAST of Engulfment and cell motility 3 vs. UniProt/SwissProt
Match: sp|Q5RCC1|ELMO2_PONAB (Engulfment and cell motility protein 2 OS=Pongo abelii OX=9601 GN=ELMO2 PE=2 SV=1)

HSP 1 Score: 114.39 bits (285), Expect = 9.749e-25
Identity = 108/391 (27.62%), Postives = 178/391 (45.52%), Query Frame = 1
Query: 1207 FEKLGFQNPSSPSRDFTE-PPGHLVFSCIKYLINNCDEIY-----HNFAKRVFNNIPLIKIAFSLVKILDRALQLTEIIDENMDGGLYLPILFHTCEIDNDLSKKFFYELFQKCFVVYAQSLIDLKFKVEDL-ELESYFLNQINEVLNCYPTSFHDLSIWLGKVRSENTRKKKLEDQITEWESNQNIQNPVINQLRTELESEYKALINKKRIRQLQERPHAFDLRSAKGVQRY---SLQLDESQSIILAKEESDPNSKVN------KWPISNIKQVLIDKACSHYNQR---KENT----FYFSITMDSRDDARDDPIRTYNFSCNHKKNYAVWIDGLNILMNKPPTSQEFKEDLLNLVRMEMKIRFLFLSKENIHHEAPALPTLPSNYDFC 2310
            ++ LGF N  +P+ DFT+ PPG L    + YL     + Y      N ++   +  P  + A  L K+L   LQ+ E+ +E  +   Y P+ F           + F ELF  C  +  ++  +++   ED  ++      QI   L   P S         K+RS  +  + L  + +E  S  + Q+P I +LR +++ E   LI ++R+ +L E      + + +  +R+    L L+  + +     + +P  +V       K P+++IK ++  K C H  ++   K+N       FSI  D        P  T NF   +K  Y +WIDGL+ L+ K  +S+  K DL  L+ MEMK+R L L    I    P +P  PS+YDF 
Sbjct:  349 YKMLGFTNHINPAMDFTQTPPGMLALDNMLYLAKVHQDTYIRIVLENSSREDKHECPFGRSAIELTKMLCEILQVGELPNEGRND--YHPMFF--------THDRAFEELFGICIQLLNKTWKEMRATAEDFNKVMQVVREQITRALPSKPNSLDQFK---SKLRSL-SYSEILRLRQSERMSQDDFQSPPIVELREKIQPEILELIKQQRLNRLCEGSSFRKIGNRRRQERFWYCRLALNH-KVLHYGDLDDNPQGEVTFESLQEKTPVADIKAIVTGKDCPHMKEKSALKQNKEVLELAFSILYD--------PDETLNFIAPNKYEYCIWIDGLSALLGKDMSSELTKSDLDTLLSMEMKLRLLDLENIQIPEAPPPIPKEPSSYDFV 716          
BLAST of Engulfment and cell motility 3 vs. UniProt/SwissProt
Match: sp|Q96JJ3|ELMO2_HUMAN (Engulfment and cell motility protein 2 OS=Homo sapiens OX=9606 GN=ELMO2 PE=1 SV=2)

HSP 1 Score: 114.005 bits (284), Expect = 1.202e-24
Identity = 108/391 (27.62%), Postives = 178/391 (45.52%), Query Frame = 1
Query: 1207 FEKLGFQNPSSPSRDFTE-PPGHLVFSCIKYLINNCDEIY-----HNFAKRVFNNIPLIKIAFSLVKILDRALQLTEIIDENMDGGLYLPILFHTCEIDNDLSKKFFYELFQKCFVVYAQSLIDLKFKVEDL-ELESYFLNQINEVLNCYPTSFHDLSIWLGKVRSENTRKKKLEDQITEWESNQNIQNPVINQLRTELESEYKALINKKRIRQLQERPHAFDLRSAKGVQRY---SLQLDESQSIILAKEESDPNSKVN------KWPISNIKQVLIDKACSHYNQR---KENT----FYFSITMDSRDDARDDPIRTYNFSCNHKKNYAVWIDGLNILMNKPPTSQEFKEDLLNLVRMEMKIRFLFLSKENIHHEAPALPTLPSNYDFC 2310
            ++ LGF N  +P+ DFT+ PPG L    + YL     + Y      N ++   +  P  + A  L K+L   LQ+ E+ +E  +   Y P+ F           + F ELF  C  +  ++  +++   ED  ++      QI   L   P S         K+RS  +  + L  + +E  S  + Q+P I +LR +++ E   LI ++R+ +L E      + + +  +R+    L L+  + +     + +P  +V       K P+++IK ++  K C H  ++   K+N       FSI  D        P  T NF   +K  Y +WIDGL+ L+ K  +S+  K DL  L+ MEMK+R L L    I    P +P  PS+YDF 
Sbjct:  349 YKMLGFTNHINPAMDFTQTPPGMLALDNMLYLAKVHQDTYIRIVLENSSREDKHECPFGRSAIELTKMLCEILQVGELPNEGRND--YHPMFF--------THDRAFEELFGICIQLLNKTWKEMRATAEDFNKVMQVVREQITRALPSKPNSLDQFK---SKLRSL-SYSEILRLRQSERMSQDDFQSPPIVELREKIQPEILELIKQQRLNRLCEGSSFRKIGNRRRQERFWYCRLALNH-KVLHYGDLDDNPQGEVTFESLQEKIPVADIKAIVTGKDCPHMKEKSALKQNKEVLELAFSILYD--------PDETLNFIAPNKYEYCIWIDGLSALLGKDMSSELTKSDLDTLLSMEMKLRLLDLENIQIPEAPPPIPKEPSSYDFV 716          
BLAST of Engulfment and cell motility 3 vs. UniProt/SwissProt
Match: sp|Q8BHL5|ELMO2_MOUSE (Engulfment and cell motility protein 2 OS=Mus musculus OX=10090 GN=Elmo2 PE=1 SV=1)

HSP 1 Score: 113.62 bits (283), Expect = 1.597e-24
Identity = 109/390 (27.95%), Postives = 180/390 (46.15%), Query Frame = 1
Query: 1207 FEKLGFQNPSSPSRDFTE-PPGHLVFSCIKYLINNCDEIY-----HNFAKRVFNNIPLIKIAFSLVKILDRALQLTEIIDENMDGGLYLPILFHTCEIDNDLSKKFFYELFQKCFVVYAQSLIDLKFKVEDL-ELESYFLNQINEVLNCYPTSFHDLSIWLGKVRSENTRKKKLEDQITEWESNQNIQNPVINQLRTELESEYKALINKKRIRQLQERPHAFDLRSAKGVQRY-SLQLDESQSIILAKEESD-PNSKVN------KWPISNIKQVLIDKACSHYNQR---KENT----FYFSITMDSRDDARDDPIRTYNFSCNHKKNYAVWIDGLNILMNKPPTSQEFKEDLLNLVRMEMKIRFLFLSKENIHHEAPALPTLPSNYDFC 2310
            ++ LGF N  +P+ DFT+ PPG L    + YL     + Y      N ++   +  P  + A  L K+L   LQ+ E+ +E  +   Y P+ F           + F ELF  C  +  ++  +++   ED  ++      QI   L   P S   L  +  K+RS  +  + L  + +E  S  + Q+P I +LR +++ E   LI ++R+ +L E      + + +  +R+   +L  +  ++   +  D P  +V       K P+++IK ++  K C H  ++   K+N       FSI  D        P  T NF   +K  Y +WIDGL+ L+ K  +S+  K DL  L+ MEMK+R L L    I    P +P  PS+YDF 
Sbjct:  361 YKMLGFTNHINPALDFTQTPPGMLALDNMLYLAKVHQDTYIRIVLENSSREDKHECPFGRSAIELTKMLCEILQVGELPNEGRND--YHPMFF--------THDRAFEELFGICIQLLNKTWKEMRATAEDFNKVMQVVREQITRALPSKPNS---LDQFKSKLRSL-SYSEILRLRQSERMSQDDFQSPPIVELREKIQPEILELIKQQRLNRLCEGSSFRKIGNRRRQERFWHCRLALNHKVLHYGDLDDNPQGEVTFESLQEKIPVADIKAIVTGKDCPHMKEKSALKQNKEVLELAFSILYD--------PDETLNFIAPNKYEYCIWIDGLSALLGKDMSSELTKSDLDTLLSMEMKLRLLDLENIQIPEAPPPVPKEPSSYDFV 728          
BLAST of Engulfment and cell motility 3 vs. UniProt/SwissProt
Match: sp|A4FUD6|ELMO2_BOVIN (Engulfment and cell motility protein 2 OS=Bos taurus OX=9913 GN=ELMO2 PE=2 SV=1)

HSP 1 Score: 111.309 bits (277), Expect = 7.986e-24
Identity = 108/391 (27.62%), Postives = 179/391 (45.78%), Query Frame = 1
Query: 1207 FEKLGFQNPSSPSRDFTE-PPGHLVFSCIKYLINNCDEIY-----HNFAKRVFNNIPLIKIAFSLVKILDRALQLTEIIDENMDGGLYLPILFHTCEIDNDLSKKFFYELFQKCFVVYAQSLIDLKFKVEDL-ELESYFLNQINEVLNCYPTSFHDLSIWLGKVRSENTRKKKLEDQITEWESNQNIQNPVINQLRTELESEYKALINKKRIRQLQERPHAFDLRSAKGVQRY---SLQLDESQSIILAKEESDPNSKVN------KWPISNIKQVLIDKACSHYNQR---KENT----FYFSITMDSRDDARDDPIRTYNFSCNHKKNYAVWIDGLNILMNKPPTSQEFKEDLLNLVRMEMKIRFLFLSKENIHHEAPALPTLPSNYDFC 2310
            ++ LGF N  +P+ DFT+ PPG L    + YL     + Y      N ++   +  P  + A  L K+L   LQ+ E+ +E  +   Y P+ F           + F ELF  C  +  ++  +++   ED  ++      QI   L   P S   L  +  K+RS  +  + L  + +E  S  + Q+P I +LR +++ E   LI ++R+ +L E      + + +  +R+    L L+  + +     + +P  +V       K P+++IK ++  K C H  ++   K+N       FSI  D        P  T NF   +K  Y +WIDGL+ L+ K  +S+  K D   L+ MEMK+R L L    I    P +P  PS+YDF 
Sbjct:  349 YKMLGFTNHINPAMDFTQTPPGMLALDNMLYLAKVHQDTYIRIVLENSSREDKHECPFGRSAIELTKMLCEILQVGELPNEGRND--YHPMFF--------THDRAFEELFGICIQLLNKTWKEMRATAEDFNKVMQVVREQITRALPSKPNS---LDQFKSKLRSL-SYSEILRLRQSERMSQDDFQSPPIVELREKIQPEILELIKQQRLNRLCEGSSFRKIGNRRRQERFWYCRLALNH-KVLHYGDLDDNPQGEVTFESLQEKIPVADIKAIVTGKDCPHMKEKSALKQNKEVLELAFSILYD--------PDETLNFIAPNKYEYCIWIDGLSALLGKDMSSELTKSDRDTLLSMEMKLRLLDLENIQIPEAPPPVPKEPSSYDFV 716          
BLAST of Engulfment and cell motility 3 vs. UniProt/SwissProt
Match: sp|Q8BPU7|ELMO1_MOUSE (Engulfment and cell motility protein 1 OS=Mus musculus OX=10090 GN=Elmo1 PE=1 SV=2)

HSP 1 Score: 95.9005 bits (237), Expect = 4.874e-19
Identity = 100/394 (25.38%), Postives = 172/394 (43.65%), Query Frame = 1
Query: 1207 FEKLGFQNPSSPSRDFTE-PPGHLVFSCIKYLINNCDEIY-----HNFAKRVFNNIPLIKIAFSLVKILDRALQLTEIIDENMDGGLYLPILFHTCEIDNDLSKKFFYELFQKCFVVYAQSLIDLKFKVEDL-ELESYFLNQINEVLNCYPTSFHDLSIWLGKVRSENTRKKKLEDQITEWESNQNIQNPVINQLRTELESEYKALINKKRIRQLQERPHAFDLRSAKGVQRY-SLQLDESQSIILAKE-ESDPNSKV------NKWPISNIKQVLIDKACSHYNQR---KENT----FYFSITMDSRDDARDDPIRTYNFSCNHKKNYAVWIDGLNILMNKPPTSQEFKEDLLNLVRMEMKIRFLFLSKENIHHEAPALPTLPSNYDF---CN 2313
            ++KLGF N  +P+ DFT+ PPG L    + Y   +  + Y      N ++   +  P  + +  L K+L   L++ E+  E  +        FH     +D S   F E F  C  +  ++  +++   ED  ++      Q+   L   P+S       L  +      K +  +++ +    ++ Q+  I +L+ +++ E   LI ++R+ +L E      L + +   ++   +L  +  ++   + E  P  +V      +K P+++IK V+  K C H  ++   K+N       FSI  DS            NF    K  Y +W DGLN L+ K   S   + DL  L+ ME+K+R L L    I    P +P  PSNYDF   CN
Sbjct:  356 YKKLGFINHVNPAMDFTQTPPGMLALDNMLYFAKHHQDAYIRIVLENSSREDKHECPFGRSSIELTKMLCEILKVGELPSETCND-------FHPMFFTHDRS---FEEFFCICIQLLNKTWKEMRATSEDFNKVMQVVKEQVMRALTTKPSSLDQFKSKLQNLSYTEILKIRQSERMNQ----EDFQSRPILELKEKIQPEILELIKQQRLNRLVEGTCFRKLNARRRQDKFWYCRLSPNHKVLHYGDLEESPQGEVPHDSLQDKLPVADIKAVVTGKDCPHMKEKGALKQNKEVLELAFSILYDSNCQ--------LNFIAPDKHEYCIWTDGLNALLGKDMMSDLTRNDLDTLLSMEIKLRLLDLENIQIPDAPPPIPKEPSNYDFVYDCN 727          
BLAST of Engulfment and cell motility 3 vs. TrEMBL
Match: A0A2U3Y7Y5 (engulfment and cell motility protein 2 OS=Leptonychotes weddellii OX=9713 GN=ELMO2 PE=4 SV=1)

HSP 1 Score: 115.546 bits (288), Expect = 7.430e-24
Identity = 109/390 (27.95%), Postives = 181/390 (46.41%), Query Frame = 1
Query: 1207 FEKLGFQNPSSPSRDFTE-PPGHLVFSCIKYLINNCDEIY-----HNFAKRVFNNIPLIKIAFSLVKILDRALQLTEIIDENMDGGLYLPILFHTCEIDNDLSKKFFYELFQKCFVVYAQSLIDLKFKVEDL-ELESYFLNQINEVLNCYPTSFHDLSIWLGKVRSENTRKKKLEDQITEWESNQNIQNPVINQLRTELESEYKALINKKRIRQLQERPHAFDLRSAKGVQRY---SLQLDESQSIILAKEESDPNSKVN------KWPISNIKQVLIDKACSHYNQR---KENT----FYFSITMDSRDDARDDPIRTYNFSCNHKKNYAVWIDGLNILMNKPPTSQEFKEDLLNLVRMEMKIRFLFLSKENIHHEAPALPTLPSNYDF 2307
            ++ LGF N  +P+ DFT+ PPG L    + YL     + Y      N ++   +  P  + A  L K+L   LQ+ E+ +E  +   Y P+ F           + F ELF  C  +  ++  +++   ED  ++      QI   L   P+S   L  +  K+RS  +  + L  + +E  S  + Q+P I +LR +++ E   LI ++R+ +L E      + + +  +R+    L L+  + +     + +P  +V       K P+++IK ++  K C H  ++   K+N       FSI  D        P  T NF   +K  Y +WIDGL+ L+ K  +S+  K DL  L+ MEMK+R L L    I    P +P  PS+YDF
Sbjct:    6 YKMLGFTNHINPAMDFTQTPPGMLALDNMLYLAKVHQDTYIRIVLENSSREDKHECPFGRSAIELTKMLCEILQVGELPNEGRND--YHPMFF--------THDRAFEELFGICIQLLNKTWKEMRATAEDFNKVMQVVREQITRALPSKPSS---LDQFKSKLRS-LSYSEILRLRQSERMSQDDFQSPPIVELREKIQPEILELIKQQRLNRLCEGSSFRKIGNRRRQERFWYCRLALNH-KVLHYGDLDDNPQGEVTFESLQEKIPVADIKAIVTGKDCPHMKEKSALKQNKEVLELAFSILYD--------PDETLNFIAPNKYEYCIWIDGLSALLGKDMSSELTKSDLDTLLSMEMKLRLLDLENIQIPEAPPPVPKEPSSYDF 372          
BLAST of Engulfment and cell motility 3 vs. TrEMBL
Match: A0A3Q7WYS3 (engulfment and cell motility protein 2 isoform X2 OS=Ursus arctos horribilis OX=116960 GN=ELMO2 PE=4 SV=1)

HSP 1 Score: 115.546 bits (288), Expect = 1.489e-23
Identity = 109/390 (27.95%), Postives = 181/390 (46.41%), Query Frame = 1
Query: 1207 FEKLGFQNPSSPSRDFTE-PPGHLVFSCIKYLINNCDEIY-----HNFAKRVFNNIPLIKIAFSLVKILDRALQLTEIIDENMDGGLYLPILFHTCEIDNDLSKKFFYELFQKCFVVYAQSLIDLKFKVEDL-ELESYFLNQINEVLNCYPTSFHDLSIWLGKVRSENTRKKKLEDQITEWESNQNIQNPVINQLRTELESEYKALINKKRIRQLQERPHAFDLRSAKGVQRY---SLQLDESQSIILAKEESDPNSKVN------KWPISNIKQVLIDKACSHYNQR---KENT----FYFSITMDSRDDARDDPIRTYNFSCNHKKNYAVWIDGLNILMNKPPTSQEFKEDLLNLVRMEMKIRFLFLSKENIHHEAPALPTLPSNYDF 2307
            ++ LGF N  +P+ DFT+ PPG L    + YL     + Y      N ++   +  P  + A  L K+L   LQ+ E+ +E  +   Y P+ F           + F ELF  C  +  ++  +++   ED  ++      QI   L   P+S   L  +  K+RS  +  + L  + +E  S  + Q+P I +LR +++ E   LI ++R+ +L E      + + +  +R+    L L+  + +     + +P  +V       K P+++IK ++  K C H  ++   K+N       FSI  D        P  T NF   +K  Y +WIDGL+ L+ K  +S+  K DL  L+ MEMK+R L L    I    P +P  PS+YDF
Sbjct:   68 YKMLGFTNHINPAMDFTQTPPGMLALDNMLYLAKVHQDTYIRIVLENSSREDKHECPFGRSAIELTKMLCEILQVGELPNEGRND--YHPMFF--------THDRAFEELFGICIQLLNKTWKEMRATAEDFNKVMQVVREQITRALPSKPSS---LDQFKSKLRSL-SYSEILRLRQSERMSQDDFQSPPIVELREKIQPEILELIKQQRLNRLCEGSSFRKIGNRRRQERFWYCRLALNH-KVLHYGDLDDNPQGEVTFESLQEKIPVADIKAIVTGKDCPHMKEKSALKQNKEVLELAFSILYD--------PDETLNFIAPNKYEYCIWIDGLSALLGKDMSSELTKSDLDTLLSMEMKLRLLDLENIQIPEAPPPVPKEPSSYDF 434          
BLAST of Engulfment and cell motility 3 vs. TrEMBL
Match: A0A5E4B9V9 (ELMO domain-containing protein OS=Marmota monax OX=9995 GN=MONAX_5E014255 PE=4 SV=1)

HSP 1 Score: 114.39 bits (285), Expect = 1.888e-23
Identity = 109/390 (27.95%), Postives = 180/390 (46.15%), Query Frame = 1
Query: 1207 FEKLGFQNPSSPSRDFTE-PPGHLVFSCIKYLINNCDEIY-----HNFAKRVFNNIPLIKIAFSLVKILDRALQLTEIIDENMDGGLYLPILFHTCEIDNDLSKKFFYELFQKCFVVYAQSLIDLKFKVEDL-ELESYFLNQINEVLNCYPTSFHDLSIWLGKVRSENTRKKKLEDQITEWESNQNIQNPVINQLRTELESEYKALINKKRIRQLQERPHAFDLRSAKGVQRY---SLQLDESQSIILAKEESDPNSKVN------KWPISNIKQVLIDKACSHYNQR---KENT----FYFSITMDSRDDARDDPIRTYNFSCNHKKNYAVWIDGLNILMNKPPTSQEFKEDLLNLVRMEMKIRFLFLSKENIHHEAPALPTLPSNYDF 2307
            ++ LGF N  +P+ DFT+ PPG L    + YL     + Y      N ++   +  P  + A  L K+L   LQ+ E+ +E  +   Y P+ F           + F ELF  C  +  ++  +++   ED  ++      QI   L   P S   L  +  K+RS  +  + L  + +E  S  + Q+P I +LR +++ E   LI ++R+ +L E      + + +  +R+    L L+  + +     + +P  +V       K P+++IK ++  K C H  ++   K+N       FSI  D        P  T NF   +K  Y +WIDGL+ L+ K  +S+  K DL  L+ MEMK+R L L    I    P +P  PS+YDF
Sbjct:    6 YKMLGFTNHINPALDFTQTPPGMLALDNMLYLAKVHQDTYIRIVLENSSREDKHECPFGRSAIELTKMLCEILQVGELPNEGRND--YHPMFF--------THDRAFEELFGICIQLLNKTWKEMRATAEDFNKVMQVVREQITRALPSKPNS---LDQFKSKLRSL-SYSEILRLRQSERMSQDDFQSPPIVELREKIQPEILELIKQQRLNRLCEGSSFRKIGNRRRQERFWYCRLALNH-KVLHYGDLDDNPQGEVTFESLQEKIPVADIKAIVTGKDCPHMKEKSALKQNKEVLELAFSILYD--------PDETLNFIAPNKYEYCIWIDGLSALLGKDMSSELTKSDLDTLLSMEMKLRLLDLENIQIPEAPPPVPKEPSSYDF 372          
BLAST of Engulfment and cell motility 3 vs. TrEMBL
Match: A0A3Q7PM88 (engulfment and cell motility protein 2 isoform X4 OS=Callorhinus ursinus OX=34884 GN=LOC112827050 PE=4 SV=1)

HSP 1 Score: 115.161 bits (287), Expect = 3.101e-23
Identity = 109/391 (27.88%), Postives = 181/391 (46.29%), Query Frame = 1
Query: 1207 FEKLGFQNPSSPSRDFTE-PPGHLVFSCIKYLINNCDEIY-----HNFAKRVFNNIPLIKIAFSLVKILDRALQLTEIIDENMDGGLYLPILFHTCEIDNDLSKKFFYELFQKCFVVYAQSLIDLKFKVEDL-ELESYFLNQINEVLNCYPTSFHDLSIWLGKVRSENTRKKKLEDQITEWESNQNIQNPVINQLRTELESEYKALINKKRIRQLQERPHAFDLRSAKGVQRY---SLQLDESQSIILAKEESDPNSKVN------KWPISNIKQVLIDKACSHYNQR---KENT----FYFSITMDSRDDARDDPIRTYNFSCNHKKNYAVWIDGLNILMNKPPTSQEFKEDLLNLVRMEMKIRFLFLSKENIHHEAPALPTLPSNYDFC 2310
            ++ LGF N  +P+ DFT+ PPG L    + YL     + Y      N ++   +  P  + A  L K+L   LQ+ E+ +E  +   Y P+ F           + F ELF  C  +  ++  +++   ED  ++      QI   L   P+S   L  +  K+RS  +  + L  + +E  S  + Q+P I +LR +++ E   LI ++R+ +L E      + + +  +R+    L L+  + +     + +P  +V       K P+++IK ++  K C H  ++   K+N       FSI  D        P  T NF   +K  Y +WIDGL+ L+ K  +S+  K DL  L+ MEMK+R L L    I    P +P  PS+YDF 
Sbjct:   96 YKMLGFTNHINPAMDFTQTPPGMLALDNMLYLAKVHQDTYIRIVLENSSREDKHECPFGRSAIELTKMLCEILQVGELPNEGRND--YHPMFF--------THDRAFEELFGICIQLLNKTWKEMRATAEDFNKVMQVVREQITRALPSKPSS---LDQFKSKLRSL-SYSEILRLRQSERMSQDDFQSPPIVELREKIQPEILELIKQQRLNRLCEGSSFRKIGNRRRQERFWYCRLALNH-KVLHYGDLDDNPQGEVTFESLQEKIPVADIKAIVTGKDCPHMKEKSALKQNKEVLELAFSILYD--------PDETLNFIAPNKYEYCIWIDGLSALLGKDMSSELTKSDLDTLLSMEMKLRLLDLENIQIPEAPPPVPKEPSSYDFV 463          
BLAST of Engulfment and cell motility 3 vs. TrEMBL
Match: A0A2U3ZKJ7 (engulfment and cell motility protein 2 isoform X4 OS=Odobenus rosmarus divergens OX=9708 GN=ELMO2 PE=4 SV=1)

HSP 1 Score: 115.161 bits (287), Expect = 3.130e-23
Identity = 109/391 (27.88%), Postives = 181/391 (46.29%), Query Frame = 1
Query: 1207 FEKLGFQNPSSPSRDFTE-PPGHLVFSCIKYLINNCDEIY-----HNFAKRVFNNIPLIKIAFSLVKILDRALQLTEIIDENMDGGLYLPILFHTCEIDNDLSKKFFYELFQKCFVVYAQSLIDLKFKVEDL-ELESYFLNQINEVLNCYPTSFHDLSIWLGKVRSENTRKKKLEDQITEWESNQNIQNPVINQLRTELESEYKALINKKRIRQLQERPHAFDLRSAKGVQRY---SLQLDESQSIILAKEESDPNSKVN------KWPISNIKQVLIDKACSHYNQR---KENT----FYFSITMDSRDDARDDPIRTYNFSCNHKKNYAVWIDGLNILMNKPPTSQEFKEDLLNLVRMEMKIRFLFLSKENIHHEAPALPTLPSNYDFC 2310
            ++ LGF N  +P+ DFT+ PPG L    + YL     + Y      N ++   +  P  + A  L K+L   LQ+ E+ +E  +   Y P+ F           + F ELF  C  +  ++  +++   ED  ++      QI   L   P+S   L  +  K+RS  +  + L  + +E  S  + Q+P I +LR +++ E   LI ++R+ +L E      + + +  +R+    L L+  + +     + +P  +V       K P+++IK ++  K C H  ++   K+N       FSI  D        P  T NF   +K  Y +WIDGL+ L+ K  +S+  K DL  L+ MEMK+R L L    I    P +P  PS+YDF 
Sbjct:   96 YKMLGFTNHINPAMDFTQTPPGMLALDNMLYLAKVHQDTYIRIVLENSSREDKHECPFGRSAIELTKMLCEILQVGELPNEGRND--YHPMFF--------THDRAFEELFGICIQLLNKTWKEMRATAEDFNKVMQVVREQITRALPSKPSS---LDQFKSKLRSL-SYSEILRLRQSERMSQDDFQSPPIVELREKIQPEILELIKQQRLNRLCEGSSFRKIGNRRRQERFWYCRLALNH-KVLHYGDLDDNPQGEVTFESLQEKIPVADIKAIVTGKDCPHMKEKSALKQNKEVLELAFSILYD--------PDETLNFIAPNKYEYCIWIDGLSALLGKDMSSELTKSDLDTLLSMEMKLRLLDLENIQIPEAPPPVPKEPSSYDFV 463          
BLAST of Engulfment and cell motility 3 vs. Ensembl Cavefish
Match: elmo1 (engulfment and cell motility protein 1 [Source:NCBI gene;Acc:103028188])

HSP 1 Score: 107.842 bits (268), Expect = 1.110e-23
Identity = 109/395 (27.59%), Postives = 178/395 (45.06%), Query Frame = 1
Query: 1207 FEKLGFQNPSSPSRDFTE-PPGHLVFSCIKYLINNCDEIY-----HNFAKRVFNNIPLIKIAFSLVKILDRALQLTEIIDENMDGGLYLPILFHTCEIDNDLSKKFFYELFQKCFVVYAQSLIDLKFKVEDL-ELESYFLNQINEVLNCYPTSFHDLSIWLGKVRSEN-TRKKKLEDQITEWESNQNIQNPVINQLRTELESEYKALINKKRIRQLQERPHAFDLRSAKGVQRY-SLQLDESQSIILAKE-ESDPNSKV------NKWPISNIKQVLIDKACSHYNQR---KENT----FYFSITMDSRDDARDDPIRTYNFSCNHKKNYAVWIDGLNILMNKPPTSQEFKEDLLNLVRMEMKIRFLFLSKENIHHEAPALPTLPSNYDF---CN 2313
            ++KLGF N  +P+ DFT+ PPG L    + Y   +  + Y      N ++   +  P  + +  L K+L   L++ E+  EN          FH     +D S   F E F  C  +  ++  +++   ED  ++      QI   L   P S         K R +N +  + L+ + +E  + ++ Q+  I +LR +++ E   LI ++R+ +L E      + S +   R+   +L  +  ++   + E  P  +V      +K P+++IK V+  K C H  ++   K+N       FSI  +S +          NF    K  Y VW DGLN L+ K  TS+  + DL  L+ MEMK+R L L    I    P +P  PSNYDF   CN
Sbjct:  317 YKKLGFINHVNPAVDFTQIPPGMLALDNMLYFARHHQDSYIRIVLENSSREDKHECPFGRSSIELTKMLCEILKVGELPSENCHD-------FHPMFFTHDRS---FVEFFCICIQLLNKTWKEMRATSEDFNKVMQVVREQITRALTAKPNSLDQF-----KSRLQNLSYTEILKIRQSERMNQEDFQSRPILELREKIQPEIMELIKQQRLNRLCEGTCFRKISSRRRQGRFWYCRLSPNHKVLHYGDLEESPQGEVPHDSLQDKLPVADIKAVVTGKDCPHMKEKGALKQNKEVLELAFSILYESDE--------YLNFIAPDKHEYCVWTDGLNALLGKEMTSEFTRSDLDTLLNMEMKLRLLDLENIQIPEAPPPIPKEPSNYDFVYDCN 688          
BLAST of Engulfment and cell motility 3 vs. Ensembl Cavefish
Match: elmo1 (engulfment and cell motility protein 1 [Source:NCBI gene;Acc:103028188])

HSP 1 Score: 105.916 bits (263), Expect = 3.909e-23
Identity = 108/395 (27.34%), Postives = 178/395 (45.06%), Query Frame = 1
Query: 1207 FEKLGFQNPSSPSRDFTE-PPGHLVFSCIKYLINNCDEIY-----HNFAKRVFNNIPLIKIAFSLVKILDRALQLTEIIDENMDGGLYLPILFHTCEIDNDLSKKFFYELFQKCFVVYAQSLIDLKFKVEDL-ELESYFLNQINEVLNCYPTSFHDLSIWLGKVRSEN-TRKKKLEDQITEWESNQNIQNPVINQLRTELESEYKALINKKRIRQLQERPHAFDLRSAKGVQRY-SLQLDESQSIILAKE-ESDPNSKV------NKWPISNIKQVLIDKACSHYNQR---KENT----FYFSITMDSRDDARDDPIRTYNFSCNHKKNYAVWIDGLNILMNKPPTSQEFKEDLLNLVRMEMKIRFLFLSKENIHHEAPALPTLPSNYDF---CN 2313
            ++KLGF N  +P+ DFT+ PPG L    + Y   +  + Y      N ++   +  P  + +  L K+L   L++ E+  EN          FH     +D S   F E F  C  +  ++  +++   ED  ++      QI   L   P S         K R +N +  + L+ + +E  + ++ Q+  I +LR +++ E   LI ++R+ +L E      + S +   ++   +L  +  ++   + E  P  +V      +K P+++IK V+  K C H  ++   K+N       FSI  +S +          NF    K  Y VW DGLN L+ K  TS+  + DL  L+ MEMK+R L L    I    P +P  PSNYDF   CN
Sbjct:  355 YKKLGFINHVNPAVDFTQIPPGMLALDNMLYFARHHQDSYIRIVLENSSREDKHECPFGRSSIELTKMLCEILKVGELPSENCHD-------FHPMFFTHDRS---FVEFFCICIQLLNKTWKEMRATSEDFNKVMQVVREQITRALTAKPNSLDQF-----KSRLQNLSYTEILKIRQSERMNQEDFQSRPILELREKIQPEIMELIKQQRLNRLCEGTCFRKISSRRRQDKFWYCRLSPNHKVLHYGDLEESPQGEVPHDSLQDKLPVADIKAVVTGKDCPHMKEKGALKQNKEVLELAFSILYESDE--------YLNFIAPDKHEYCVWTDGLNALLGKEMTSEFTRSDLDTLLNMEMKLRLLDLENIQIPEAPPPIPKEPSNYDFVYDCN 726          
BLAST of Engulfment and cell motility 3 vs. Ensembl Cavefish
Match: elmo1 (engulfment and cell motility protein 1 [Source:NCBI gene;Acc:103028188])

HSP 1 Score: 105.916 bits (263), Expect = 4.065e-23
Identity = 108/395 (27.34%), Postives = 178/395 (45.06%), Query Frame = 1
Query: 1207 FEKLGFQNPSSPSRDFTE-PPGHLVFSCIKYLINNCDEIY-----HNFAKRVFNNIPLIKIAFSLVKILDRALQLTEIIDENMDGGLYLPILFHTCEIDNDLSKKFFYELFQKCFVVYAQSLIDLKFKVEDL-ELESYFLNQINEVLNCYPTSFHDLSIWLGKVRSEN-TRKKKLEDQITEWESNQNIQNPVINQLRTELESEYKALINKKRIRQLQERPHAFDLRSAKGVQRY-SLQLDESQSIILAKE-ESDPNSKV------NKWPISNIKQVLIDKACSHYNQR---KENT----FYFSITMDSRDDARDDPIRTYNFSCNHKKNYAVWIDGLNILMNKPPTSQEFKEDLLNLVRMEMKIRFLFLSKENIHHEAPALPTLPSNYDF---CN 2313
            ++KLGF N  +P+ DFT+ PPG L    + Y   +  + Y      N ++   +  P  + +  L K+L   L++ E+  EN          FH     +D S   F E F  C  +  ++  +++   ED  ++      QI   L   P S         K R +N +  + L+ + +E  + ++ Q+  I +LR +++ E   LI ++R+ +L E      + S +   ++   +L  +  ++   + E  P  +V      +K P+++IK V+  K C H  ++   K+N       FSI  +S +          NF    K  Y VW DGLN L+ K  TS+  + DL  L+ MEMK+R L L    I    P +P  PSNYDF   CN
Sbjct:  357 YKKLGFINHVNPAVDFTQIPPGMLALDNMLYFARHHQDSYIRIVLENSSREDKHECPFGRSSIELTKMLCEILKVGELPSENCHD-------FHPMFFTHDRS---FVEFFCICIQLLNKTWKEMRATSEDFNKVMQVVREQITRALTAKPNSLDQF-----KSRLQNLSYTEILKIRQSERMNQEDFQSRPILELREKIQPEIMELIKQQRLNRLCEGTCFRKISSRRRQDKFWYCRLSPNHKVLHYGDLEESPQGEVPHDSLQDKLPVADIKAVVTGKDCPHMKEKGALKQNKEVLELAFSILYESDE--------YLNFIAPDKHEYCVWTDGLNALLGKEMTSEFTRSDLDTLLNMEMKLRLLDLENIQIPEAPPPIPKEPSNYDFVYDCN 728          
BLAST of Engulfment and cell motility 3 vs. Ensembl Cavefish
Match: elmo1 (engulfment and cell motility protein 1 [Source:NCBI gene;Acc:103028188])

HSP 1 Score: 105.916 bits (263), Expect = 4.429e-23
Identity = 108/395 (27.34%), Postives = 178/395 (45.06%), Query Frame = 1
Query: 1207 FEKLGFQNPSSPSRDFTE-PPGHLVFSCIKYLINNCDEIY-----HNFAKRVFNNIPLIKIAFSLVKILDRALQLTEIIDENMDGGLYLPILFHTCEIDNDLSKKFFYELFQKCFVVYAQSLIDLKFKVEDL-ELESYFLNQINEVLNCYPTSFHDLSIWLGKVRSEN-TRKKKLEDQITEWESNQNIQNPVINQLRTELESEYKALINKKRIRQLQERPHAFDLRSAKGVQRY-SLQLDESQSIILAKE-ESDPNSKV------NKWPISNIKQVLIDKACSHYNQR---KENT----FYFSITMDSRDDARDDPIRTYNFSCNHKKNYAVWIDGLNILMNKPPTSQEFKEDLLNLVRMEMKIRFLFLSKENIHHEAPALPTLPSNYDF---CN 2313
            ++KLGF N  +P+ DFT+ PPG L    + Y   +  + Y      N ++   +  P  + +  L K+L   L++ E+  EN          FH     +D S   F E F  C  +  ++  +++   ED  ++      QI   L   P S         K R +N +  + L+ + +E  + ++ Q+  I +LR +++ E   LI ++R+ +L E      + S +   ++   +L  +  ++   + E  P  +V      +K P+++IK V+  K C H  ++   K+N       FSI  +S +          NF    K  Y VW DGLN L+ K  TS+  + DL  L+ MEMK+R L L    I    P +P  PSNYDF   CN
Sbjct:  369 YKKLGFINHVNPAVDFTQIPPGMLALDNMLYFARHHQDSYIRIVLENSSREDKHECPFGRSSIELTKMLCEILKVGELPSENCHD-------FHPMFFTHDRS---FVEFFCICIQLLNKTWKEMRATSEDFNKVMQVVREQITRALTAKPNSLDQF-----KSRLQNLSYTEILKIRQSERMNQEDFQSRPILELREKIQPEIMELIKQQRLNRLCEGTCFRKISSRRRQDKFWYCRLSPNHKVLHYGDLEESPQGEVPHDSLQDKLPVADIKAVVTGKDCPHMKEKGALKQNKEVLELAFSILYESDE--------YLNFIAPDKHEYCVWTDGLNALLGKEMTSEFTRSDLDTLLNMEMKLRLLDLENIQIPEAPPPIPKEPSNYDFVYDCN 740          
BLAST of Engulfment and cell motility 3 vs. Ensembl Cavefish
Match: elmo1 (engulfment and cell motility protein 1 [Source:NCBI gene;Acc:103028188])

HSP 1 Score: 105.916 bits (263), Expect = 4.429e-23
Identity = 108/395 (27.34%), Postives = 178/395 (45.06%), Query Frame = 1
Query: 1207 FEKLGFQNPSSPSRDFTE-PPGHLVFSCIKYLINNCDEIY-----HNFAKRVFNNIPLIKIAFSLVKILDRALQLTEIIDENMDGGLYLPILFHTCEIDNDLSKKFFYELFQKCFVVYAQSLIDLKFKVEDL-ELESYFLNQINEVLNCYPTSFHDLSIWLGKVRSEN-TRKKKLEDQITEWESNQNIQNPVINQLRTELESEYKALINKKRIRQLQERPHAFDLRSAKGVQRY-SLQLDESQSIILAKE-ESDPNSKV------NKWPISNIKQVLIDKACSHYNQR---KENT----FYFSITMDSRDDARDDPIRTYNFSCNHKKNYAVWIDGLNILMNKPPTSQEFKEDLLNLVRMEMKIRFLFLSKENIHHEAPALPTLPSNYDF---CN 2313
            ++KLGF N  +P+ DFT+ PPG L    + Y   +  + Y      N ++   +  P  + +  L K+L   L++ E+  EN          FH     +D S   F E F  C  +  ++  +++   ED  ++      QI   L   P S         K R +N +  + L+ + +E  + ++ Q+  I +LR +++ E   LI ++R+ +L E      + S +   ++   +L  +  ++   + E  P  +V      +K P+++IK V+  K C H  ++   K+N       FSI  +S +          NF    K  Y VW DGLN L+ K  TS+  + DL  L+ MEMK+R L L    I    P +P  PSNYDF   CN
Sbjct:  369 YKKLGFINHVNPAVDFTQIPPGMLALDNMLYFARHHQDSYIRIVLENSSREDKHECPFGRSSIELTKMLCEILKVGELPSENCHD-------FHPMFFTHDRS---FVEFFCICIQLLNKTWKEMRATSEDFNKVMQVVREQITRALTAKPNSLDQF-----KSRLQNLSYTEILKIRQSERMNQEDFQSRPILELREKIQPEIMELIKQQRLNRLCEGTCFRKISSRRRQDKFWYCRLSPNHKVLHYGDLEESPQGEVPHDSLQDKLPVADIKAVVTGKDCPHMKEKGALKQNKEVLELAFSILYESDE--------YLNFIAPDKHEYCVWTDGLNALLGKEMTSEFTRSDLDTLLNMEMKLRLLDLENIQIPEAPPPIPKEPSNYDFVYDCN 740          
BLAST of Engulfment and cell motility 3 vs. Ensembl Sea Lamprey
Match: elmo1 (engulfment and cell motility 1 (ced-12 homolog, C. elegans) [Source:ZFIN;Acc:ZDB-GENE-040426-2069])

HSP 1 Score: 101.293 bits (251), Expect = 2.829e-22
Identity = 103/388 (26.55%), Postives = 168/388 (43.30%), Query Frame = 1
Query: 1201 QVFEKLGFQNPSSPSRDFTE-PPGHLVFSCIKYLINNCDEIY-----HNFAKRVFNNIPLIKIAFSLVKILDRALQLTEIIDENMDGGLYLPILFHTCEIDNDLSKKFFYELFQKCFVVYAQSLIDLKFKVEDLE-LESYFLNQINEVLNCYPTSFHDLSIWLGKVRSENTRKKKLEDQITEWESNQNIQNPVINQLRTELESEYKALINKKRIRQLQERPHAFDL-RSAKGVQRYSLQLDESQSIILAKEESDPNSKV-------NKWPISNIKQVLIDKACSHYNQRKENT----FYFSITMDSRDDARDDPIRTYNFSCNHKKNYAVWIDGLNILMNKPPTSQEFKEDLLNLVRMEMKIRFLFLSKENIHHEAPALPTLPSNYDF 2307
            Q ++KLGF N  +P+ DFT  PPG L   C+ Y      + Y      N  +   +  P  + +  L +I+   +++ E   E   G  Y P+ F     DN      F ELF  C  +  ++  +++   ED + +      QI   L   P S     + L  +      K +  +++ + E +     P+I +LR ++  E   LI ++R+ +L E      + ++ +  + +  +L  +  + L   + +  SK         K PI++IK V+  K C H  + +++       FSI  D        P  + NF       Y VW DGLN L+ +   S+    DL  L+ MEMK+R L L    I   AP +P  PSNYDF
Sbjct:  358 QDYKKLGFLNSVNPALDFTATPPGILALDCMLYFAKQHQDSYIRLVLENSCREDRHECPFGRSSIELTRIMCEIMRIREPPSET--GQDYYPMYFTH---DN-----AFQELFCVCVQLLNKTWKEMRATFEDFDKVLQVVREQIVRCLLNKPNSMDQFRVHLHNLGYAEILKIRQSERMNQEEGDFKAA-PII-ELREKILPEVLELIKQQRLNRLCEGTTFRKIGKNRRQDKLWYCRLSPNHKV-LHYADVEEGSKAPAIEALQEKLPIADIKMVVTGKDCPHMKEVRKSKDVMDLAFSILYD--------PDESLNFIAKSPDEYCVWTDGLNALLGREMVSKATCSDLEVLLNMEMKLRLLDLENIQIPETAPVVPVPPSNYDF 724          
BLAST of Engulfment and cell motility 3 vs. Ensembl Nematostella
Match: EDO35451 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SLG8])

HSP 1 Score: 91.2781 bits (225), Expect = 6.310e-19
Identity = 113/405 (27.90%), Postives = 181/405 (44.69%), Query Frame = 1
Query: 1174 SGNDSDTDFQVFEKLGFQNPSSPSRDFTE-PPGHLVFSCIKYLINNCDEIY-----HNFAKRVFNNIPLIKIAFSLVKILDRALQLT-EIIDENMDGGLYLPILFHTCEIDNDLSKKFFYELFQKCFVVYAQSLIDLKFKVEDL-ELESYFLNQINEVLNCYPTSFHDLSIWLGKVRSENTRKKKLEDQITEWESNQNIQNPVINQLRTELESEYKALINKKRIRQLQERPHAFDLRSAKGVQ------RYSLQL--------DESQSIILAKEESDPNSKVNKWPISNIKQVLIDKACSHY----NQRKENTFYFSITMDSRDDARDDPIRTYNFSCNHKKNYAVWIDGLNILMNKPPTSQEFKEDLLNLVRMEMKIRFLFLSKENIHHEAPALPTLPSNYDFC 2310
            +GN S      F++LGF N  SP  DF++ PPG L    + Y      + Y      N ++      P  + + +L K+L   L++T E   E  D   Y PI F T   DN      F E F  C  +  ++  +++    D   + +    QI   L    ++      ++  +    T+  KL  Q     +   +Q P + +LR ++  E K ++ ++R+ QL+E    FD    + V+      R S  L        +E Q+  L   +       NK PI+ IKQ+L+ K   H     + +K +  +FS+  +     RDD     NF   +   +A+W+DG++ L+NK   S+E +EDL  L+ MEMK+R L L   +I    PA+P  P NYDF 
Sbjct:  334 AGNQSKD----FKRLGFVNIDSPVMDFSDSPPGLLPMHAMIYFSKKHQDQYIKVVMENLSRGDECECPFAQSSIALTKMLCEILKITGEPPSETSDE--YYPIFFTT---DNA-----FEEFFCICIQLVNRTWREMRATSGDFNRVMAVVKEQIVRSLGERHSTMDQYKNYVSNLGF--TQILKLMQQEFHERTMLELQAPPVVELRQQILPELKNIVRQQRLEQLKEG-RLFDKGGKRHVRDKFWFCRLSPNLKFLHYGDCEEGQTPALEALQ-------NKLPIAGIKQLLVGKDYPHAKDIKDWKKLHHLFFSLEYE-----RDDKTEYLNFIAPNPNVFAIWVDGISTLLNKEMPSKEAQEDLETLLNMEMKLRLLDLENISIPESPPAIPPEPPNYDFV 709          
BLAST of Engulfment and cell motility 3 vs. Ensembl Medaka
Match: elmo1 (engulfment and cell motility protein 1 [Source:NCBI gene;Acc:101169868])

HSP 1 Score: 102.834 bits (255), Expect = 3.883e-22
Identity = 107/395 (27.09%), Postives = 178/395 (45.06%), Query Frame = 1
Query: 1207 FEKLGFQNPSSPSRDFTE-PPGHLVFSCIKYLINNCDEIY-----HNFAKRVFNNIPLIKIAFSLVKILDRALQLTEIIDENMDGGLYLPILFHTCEIDNDLSKKFFYELFQKCFVVYAQSLIDLKFKVEDL-ELESYFLNQINEVLNCYPTSFHDLSIWLGKVRSEN-TRKKKLEDQITEWESNQNIQNPVINQLRTELESEYKALINKKRIRQLQERPHAFDLRSAKGVQRY-SLQLDESQSIILAKE-ESDPNSKV------NKWPISNIKQVLIDKACSHYNQR---KENT----FYFSITMDSRDDARDDPIRTYNFSCNHKKNYAVWIDGLNILMNKPPTSQEFKEDLLNLVRMEMKIRFLFLSKENIHHEAPALPTLPSNYDF---CN 2313
            ++KLGF N  +P+ DFT+ PPG L    + Y   +  + Y      N ++   +  P  + +  L K+L   L++ E+  EN          FH     +D S   F E F  C  +  ++  +++   ED  ++      QI   L+  P S         K R +N +  + L+ + +E  + ++ Q+  I +LR +++ E   LI ++R+ +L +      + S +   ++   +L  +  ++   + E  P  +V      +K P+++IK V+  K C H  ++   K+N       FS+  +S +          NF    K  Y VW DGLN L+ K  TS   K DL  L+ MEMK+R L L    I    P +P  PSNYDF   CN
Sbjct:  355 YKKLGFINHVNPAVDFTQIPPGMLALDNMLYFARHHQDAYIRIVLENSSREDKHECPFGRSSIELTKMLCEILKVGELPSENCHD-------FHPMFFTHDRS---FAEFFCICIQLLNKTWKEMRATNEDFNKVMQVVREQIMRALSLKPNSLDQF-----KSRLQNLSYTEILKIRQSERMNQEDFQSRPILELREKIQPEIMELIKQQRLNRLCDGTCFRKISSRRRQDKFWYCRLSPNHKVLHYGDLEESPQGEVPHDSLQDKLPVADIKAVITGKDCPHMKEKGALKQNKEVLELAFSVLYESDE--------YLNFIAPDKHEYCVWTDGLNALLGKEMTSDYTKSDLDTLLSMEMKLRLLDLENIQIPDAPPPIPKEPSNYDFVYDCN 726          
BLAST of Engulfment and cell motility 3 vs. Ensembl Medaka
Match: elmo1 (engulfment and cell motility protein 1 [Source:NCBI gene;Acc:101169868])

HSP 1 Score: 102.834 bits (255), Expect = 3.888e-22
Identity = 107/395 (27.09%), Postives = 178/395 (45.06%), Query Frame = 1
Query: 1207 FEKLGFQNPSSPSRDFTE-PPGHLVFSCIKYLINNCDEIY-----HNFAKRVFNNIPLIKIAFSLVKILDRALQLTEIIDENMDGGLYLPILFHTCEIDNDLSKKFFYELFQKCFVVYAQSLIDLKFKVEDL-ELESYFLNQINEVLNCYPTSFHDLSIWLGKVRSEN-TRKKKLEDQITEWESNQNIQNPVINQLRTELESEYKALINKKRIRQLQERPHAFDLRSAKGVQRY-SLQLDESQSIILAKE-ESDPNSKV------NKWPISNIKQVLIDKACSHYNQR---KENT----FYFSITMDSRDDARDDPIRTYNFSCNHKKNYAVWIDGLNILMNKPPTSQEFKEDLLNLVRMEMKIRFLFLSKENIHHEAPALPTLPSNYDF---CN 2313
            ++KLGF N  +P+ DFT+ PPG L    + Y   +  + Y      N ++   +  P  + +  L K+L   L++ E+  EN          FH     +D S   F E F  C  +  ++  +++   ED  ++      QI   L+  P S         K R +N +  + L+ + +E  + ++ Q+  I +LR +++ E   LI ++R+ +L +      + S +   ++   +L  +  ++   + E  P  +V      +K P+++IK V+  K C H  ++   K+N       FS+  +S +          NF    K  Y VW DGLN L+ K  TS   K DL  L+ MEMK+R L L    I    P +P  PSNYDF   CN
Sbjct:  343 YKKLGFINHVNPAVDFTQIPPGMLALDNMLYFARHHQDAYIRIVLENSSREDKHECPFGRSSIELTKMLCEILKVGELPSENCHD-------FHPMFFTHDRS---FAEFFCICIQLLNKTWKEMRATNEDFNKVMQVVREQIMRALSLKPNSLDQF-----KSRLQNLSYTEILKIRQSERMNQEDFQSRPILELREKIQPEIMELIKQQRLNRLCDGTCFRKISSRRRQDKFWYCRLSPNHKVLHYGDLEESPQGEVPHDSLQDKLPVADIKAVITGKDCPHMKEKGALKQNKEVLELAFSVLYESDE--------YLNFIAPDKHEYCVWTDGLNALLGKEMTSDYTKSDLDTLLSMEMKLRLLDLENIQIPDAPPPIPKEPSNYDFVYDCN 714          
BLAST of Engulfment and cell motility 3 vs. Ensembl Medaka
Match: elmo2 (engulfment and cell motility protein 2 [Source:NCBI gene;Acc:101156647])

HSP 1 Score: 102.064 bits (253), Expect = 7.808e-22
Identity = 101/386 (26.17%), Postives = 169/386 (43.78%), Query Frame = 1
Query: 1207 FEKLGFQNPSSPSRDFTE-PPGHLVFSCIKYLINNCDEIY-----HNFAKRVFNNIPLIKIAFSLVKILDRALQLTEIIDENMDGGLYLPILFHTCEIDNDLSKKFFYELFQKCFVVYAQSLIDLKFKVEDL-ELESYFLNQINEVLNCYPTSFHDLSIWLGKVRSENTRKKKLEDQITEWESNQNIQNPVINQLRTELESEYKALINKKRIRQLQERPHAFDLRSAKGVQRY---SLQLDESQSIILAKEESDPNSKV------NKWPISNIKQVLIDKACSHYNQR---KENTFYFSITMDSRDDARDDPIRTYNFSCNHKKNYAVWIDGLNILMNKPPTSQEFKEDLLNLVRMEMKIRFLFLSKENIHHEAPALPTLPSNYDF 2307
            ++ LGF N  +P+ DFT+ PPG L    + YL     + Y      N ++   +  P  + A  L + L   LQ+ E+ +E  +   Y P+ F           + + E F  C  +  ++  +++   ED  ++      QI   L   P+S   L     K+R  N   + L  + +E  S  ++ +P I +LR  +  E   LI ++R+ +L E      L + +  +++    L L+  + +     +  P  +V      +K P+S+IK VL  K C H  ++   K+N     +          DP  T NF   +K  Y +W DGL  L+ +   S   + DL  L+ MEMK+R L L    I    P +P  PS+Y+F
Sbjct:  340 YKMLGFTNHVNPAMDFTQTPPGMLALDNMLYLAKVHQDTYIRIVLENSSREDKHECPFGRCAIELTRTLCEILQVGELPNEGCND--YHPMFF--------THDRAWEEFFCVCIQLLNKTWKEMRATSEDFNKVMQVVREQITRALAMKPSSIDQLK---NKLRGLNY-SEILRLRQSERMSQDDLHSPPIIELRERILPEILELIKQQRLNRLCEGSCFRKLGNRRRQEKFWFCRLSLNH-KVLHYGDLDESPQGEVPFELLSDKIPVSDIKSVLTGKDCPHMKEKSALKQNKEVLELAFS----VLYDPDETLNFVAPNKYEYCIWTDGLCALLGREMGSDLTRSDLDTLISMEMKLRLLDLENITIPEAPPPVPKEPSSYNF 706          
BLAST of Engulfment and cell motility 3 vs. Ensembl Medaka
Match: elmo3 (engulfment and cell motility protein 3 [Source:NCBI gene;Acc:101173701])

HSP 1 Score: 98.9821 bits (245), Expect = 4.331e-21
Identity = 98/387 (25.32%), Postives = 172/387 (44.44%), Query Frame = 1
Query: 1207 FEKLGFQNPSSPSRDFTE-PPGHLVFSCIKYLINNCDEIYHNF-----AKRVFNNIPLIKIAFSLVKILDRALQLTEIIDENMDGGLYLPILFHTCEIDNDLSKKFFYELFQKCFVVYAQSLIDLKFKVEDLE-LESYFLNQINEVLNCYPTSFHDLSIWLGKVRSENTRKKKLEDQITEWESNQNIQNPVINQLRTELESEYKALINKKRIRQLQERPHAFDLRSAKGVQR-YSLQLDESQSII----LAKEESDPNSKV--NKWPISNIKQVLIDKACSHY--NQRKENT---FYFSITMDSRDDARDDPIRTYNFSCNHKKNYAVWIDGLNILMNKPPTSQEFKEDLLNLVRMEMKIRFLFLSKENIHHEAPALPTLPSNYDFC 2310
            F+KLGF N S+P +D    PPG L    + Y      E +  F     ++   +  P  + +  L  IL   L++ E   E   G  Y  I F+          K   ELF  C  +  ++  +++   ED + +      QI   L   PTS   L  +  KV + N  +     Q       + +  PV+ +L+  L+ E   LI ++R+ +L +      + S +   + +  +L  +  ++    + ++  +P  +    K P+++IK +LI K C H   N+ K+N      F+I  D  +        + NF    + ++ +W DGL++L+ +  +S+  + +L  L+ ME+K+R L L    I   AP +P  PSNY+FC
Sbjct:  196 FKKLGFSNNSNPGQDLVRTPPGLLALDTMCYFATQYTEAFKRFVLENSSREDKHECPFARSSIQLTHILCEILRIGEPASET--GSDYHTIFFN--------QDKLLEELFCVCIQLLNKTWKEMRATQEDFDKVMQVVREQITRTLANKPTS---LEFFKNKVNALNYSEILKLRQTERLHQEETLAPPVL-ELKERLKPELLELIRQQRLNRLCQGTMFRKISSRRRQDKLWFCRLSPNHKMLHYGDVDEDAENPPIETLQEKIPVADIKGLLIGKDCPHMKENKGKQNKVLDLAFTIIYDVEE-------YSLNFIAPSRTDFCLWTDGLSVLLGREMSSEAMRSELEILLSMEIKLRLLDLENIPIPDSAPVVPKPPSNYNFC 561          
BLAST of Engulfment and cell motility 3 vs. Ensembl Medaka
Match: elmo3 (engulfment and cell motility protein 3 [Source:NCBI gene;Acc:101173701])

HSP 1 Score: 99.3673 bits (246), Expect = 5.578e-21
Identity = 98/388 (25.26%), Postives = 172/388 (44.33%), Query Frame = 1
Query: 1207 FEKLGFQNPSSPSRDFTE-PPGHLVFSCIKYLINNCDEIYHNF-----AKRVFNNIPLIKIAFSLVKILDRALQLTEIIDENMDGGLYLPILFHTCEIDNDLSKKFFYELFQKCFVVYAQSLIDLKFKVEDLE-LESYFLNQINEVLNCYPTSFHDLSIWLGKVRSENTRKKKLEDQITEWESNQNIQNPVINQLRTELESEYKALINKKRIRQLQERPHAFDLRSAKGVQR-YSLQLDESQSII----LAKEESDPNSKV--NKWPISNIKQVLIDKACSHY--NQRKENT----FYFSITMDSRDDARDDPIRTYNFSCNHKKNYAVWIDGLNILMNKPPTSQEFKEDLLNLVRMEMKIRFLFLSKENIHHEAPALPTLPSNYDFC 2310
            F+KLGF N S+P +D    PPG L    + Y      E +  F     ++   +  P  + +  L  IL   L++ E   E   G  Y  I F+          K   ELF  C  +  ++  +++   ED + +      QI   L   PTS   L  +  KV + N  +     Q       + +  PV+ +L+  L+ E   LI ++R+ +L +      + S +   + +  +L  +  ++    + ++  +P  +    K P+++IK +LI K C H   N+ K+N       F+I  D  +        + NF    + ++ +W DGL++L+ +  +S+  + +L  L+ ME+K+R L L    I   AP +P  PSNY+FC
Sbjct:  368 FKKLGFSNNSNPGQDLVRTPPGLLALDTMCYFATQYTEAFKRFVLENSSREDKHECPFARSSIQLTHILCEILRIGEPASET--GSDYHTIFFN--------QDKLLEELFCVCIQLLNKTWKEMRATQEDFDKVMQVVREQITRTLANKPTS---LEFFKNKVNALNYSEILKLRQTERLHQEETLAPPVL-ELKERLKPELLELIRQQRLNRLCQGTMFRKISSRRRQDKLWFCRLSPNHKMLHYGDVDEDAENPPIETLQEKIPVADIKGLLIGKDCPHMKENKGKQNKEVLDLAFTIIYDVEE-------YSLNFIAPSRTDFCLWTDGLSVLLGREMSSEAMRSELEILLSMEIKLRLLDLENIPIPDSAPVVPKPPSNYNFC 734          
BLAST of Engulfment and cell motility 3 vs. Planmine SMEST
Match: SMESG000039535.1 (SMESG000039535.1)

HSP 1 Score: 1526.92 bits (3952), Expect = 0.000e+0
Identity = 745/747 (99.73%), Postives = 747/747 (100.00%), Query Frame = 1
Query:   73 MSIYQFAVTFENNSRHYKENFNKDIGPKDLINRFAKDFGLDYNSLDEYQLIVHIKEEAPFYLKDHNVQCLPRVYMMDLCPLPGKEVSDIKIQMTSKDPEVVKKALECLAKRLSVQEFVILCIGSGLHIDLFRLVEKVMQIKNGNEELSVLTMKVFAEFIVYTNRKEDFEAEPEADERPYISWLNIKAETIRSTLDYCKTSQNFNGIDSSLKVLVRYVNQNDTLRDFIFKNLDSVFIFNLFEKLHKSINILRPLKCSIQISLISLINCSFASSRESKDKFIEKLNDYFGKDKFRGLKENIDLITRKLREFPSELPPAGCSVPSKEENDLKQELTKLQYFILLPVYWDFSDTNYDGPKINDLELFKQMLSGNDSDTDFQVFEKLGFQNPSSPSRDFTEPPGHLVFSCIKYLINNCDEIYHNFAKRVFNNIPLIKIAFSLVKILDRALQLTEIIDENMDGGLYLPILFHTCEIDNDLSKKFFYELFQKCFVVYAQSLIDLKFKVEDLELESYFLNQINEVLNCYPTSFHDLSIWLGKVRSENTRKKKLEDQITEWESNQNIQNPVINQLRTELESEYKALINKKRIRQLQERPHAFDLRSAKGVQRYSLQLDESQSIILAKEESDPNSKVNKWPISNIKQVLIDKACSHYNQRKENTFYFSITMDSRDDARDDPIRTYNFSCNHKKNYAVWIDGLNILMNKPPTSQEFKEDLLNLVRMEMKIRFLFLSKENIHHEAPALPTLPSNYDFCN 2313
            MSIYQFAVTFENNSRHYKENFNKDIGPKDLINRFAKDFGLDYNSLDEYQLIVHIKEEAPFYLKDHNVQCLPRVYMMDLCPLPGKEVSDIKIQMTSKDPEVVKKALECLAKRLSVQEFVILCIGSGLHIDLFRLVEKVMQIKNGNEELSVLTMKVFAEFIVYTNRKEDFEAEPEADERPYISWLNIKAETIRSTLDYCKTSQNFNGIDSSLKVLVRYVNQNDTLRDFIFKNLDSVFIFNLFEKLHKSINILRPLKCSIQISLISLINCSFASSRESKDKFIEKLNDYFGKDKFRGLKENIDLITRKLREFPSELPPAGCSVPSKEENDLKQELTKLQYFILLPVYWDFSDTNYDGPKINDLELFKQMLSGNDSDTDFQVFEKLGFQNPSSPSRDFTEPPGHLVFSCIKYLINNCDEIYHNFAKRVFNNIPLIKIAFSLVKILDRALQLTEIIDENMDGGLYLPILFHTCEIDNDLSKKFFYELFQKCFVVYAQSLIDLKFKVEDLELESYFLNQINEVLNCYPTSFHDLSIWLGKVRSENTRKKKLEDQITEWESNQNIQNPVINQLRTELESEYKALINKKRIRQLQERPHAFDLRSAKGVQRYSLQLDESQSIILAKEESDPNSKVNKWPISNIKQVLIDKACSHYNQRKENTFYFSITMDSRDDARDDP++TYNFSCNHKKNYAVWIDGLNILMNKPPTSQEFKEDLLNLVRMEMKIRFLFLSKENIHHEAPALPTLPSNYDFCN
Sbjct:    1 MSIYQFAVTFENNSRHYKENFNKDIGPKDLINRFAKDFGLDYNSLDEYQLIVHIKEEAPFYLKDHNVQCLPRVYMMDLCPLPGKEVSDIKIQMTSKDPEVVKKALECLAKRLSVQEFVILCIGSGLHIDLFRLVEKVMQIKNGNEELSVLTMKVFAEFIVYTNRKEDFEAEPEADERPYISWLNIKAETIRSTLDYCKTSQNFNGIDSSLKVLVRYVNQNDTLRDFIFKNLDSVFIFNLFEKLHKSINILRPLKCSIQISLISLINCSFASSRESKDKFIEKLNDYFGKDKFRGLKENIDLITRKLREFPSELPPAGCSVPSKEENDLKQELTKLQYFILLPVYWDFSDTNYDGPKINDLELFKQMLSGNDSDTDFQVFEKLGFQNPSSPSRDFTEPPGHLVFSCIKYLINNCDEIYHNFAKRVFNNIPLIKIAFSLVKILDRALQLTEIIDENMDGGLYLPILFHTCEIDNDLSKKFFYELFQKCFVVYAQSLIDLKFKVEDLELESYFLNQINEVLNCYPTSFHDLSIWLGKVRSENTRKKKLEDQITEWESNQNIQNPVINQLRTELESEYKALINKKRIRQLQERPHAFDLRSAKGVQRYSLQLDESQSIILAKEESDPNSKVNKWPISNIKQVLIDKACSHYNQRKENTFYFSITMDSRDDARDDPVKTYNFSCNHKKNYAVWIDGLNILMNKPPTSQEFKEDLLNLVRMEMKIRFLFLSKENIHHEAPALPTLPSNYDFCN 747          
BLAST of Engulfment and cell motility 3 vs. Planmine SMEST
Match: SMESG000039535.1 (SMESG000039535.1)

HSP 1 Score: 1512.28 bits (3914), Expect = 0.000e+0
Identity = 740/747 (99.06%), Postives = 743/747 (99.46%), Query Frame = 1
Query:   73 MSIYQFAVTFENNSRHYKENFNKDIGPKDLINRFAKDFGLDYNSLDEYQLIVHIKEEAPFYLKDHNVQCLPRVYMMDLCPLPGKEVSDIKIQMTSKDPEVVKKALECLAKRLSVQEFVILCIGSGLHIDLFRLVEKVMQIKNGNEELSVLTMKVFAEFIVYTNRKEDFEAEPEADERPYISWLNIKAETIRSTLDYCKTSQNFNGIDSSLKVLVRYVNQNDTLRDFIFKNLDSVFIFNLFEKLHKSINILRPLKCSIQISLISLINCSFASSRESKDKFIEKLNDYFGKDKFRGLKENIDLITRKLREFPSELPPAGCSVPSKEENDLKQELTKLQYFILLPVYWDFSDTNYDGPKINDLELFKQMLSGNDSDTDFQVFEKLGFQNPSSPSRDFTEPPGHLVFSCIKYLINNCDEIYHNFAKRVFNNIPLIKIAFSLVKILDRALQLTEIIDENMDGGLYLPILFHTCEIDNDLSKKFFYELFQKCFVVYAQSLIDLKFKVEDLELESYFLNQINEVLNCYPTSFHDLSIWLGKVRSENTRKKKLEDQITEWESNQNIQNPVINQLRTELESEYKALINKKRIRQLQERPHAFDLRSAKGVQRYSLQLDESQSIILAKEESDPNSKVNKWPISNIKQVLIDKACSHYNQRKENTFYFSITMDSRDDARDDPIRTYNFSCNHKKNYAVWIDGLNILMNKPPTSQEFKEDLLNLVRMEMKIRFLFLSKENIHHEAPALPTLPSNYDFCN 2313
            MSIYQFAVTFENNSRHYKENFNKDIGPKDLINRFAKDFGLDYNSLDEYQLIVHIKEEAPFYLKDHNVQCLPRVYMMDLCPLPGKEVSDIKIQMTSKDPEVVKKALECLAKRLSVQEFVILCIGSGLHIDLFRLVEKV+    GNEELSVLTMKVFAEFIVYTNRKEDFEAEPEADERPYISWLNIKAETIRSTLDYCKTSQNFNGIDSSLKVLVRYVNQNDTLRDFIFKNLDSVFIFNLFEKLHKSINILRPLKCSIQISLISLINCSFASSRESKDKFIEKLNDYFGKDKFRGLKENIDLITRKLREFPSELPPAGCSVPSKEENDLKQELTKLQYFILLPVYWDFSDTNYDGPKINDLELFKQMLSGNDSDTDFQVFEKLGFQNPSSPSRDFTEPPGHLVFSCIKYLINNCDEIYHNFAKRVFNNIPLIKIAFSLVKILDRALQLTEIIDENMDGGLYLPILFHTCEIDNDLSKKFFYELFQKCFVVYAQSLIDLKFKVEDLELESYFLNQINEVLNCYPTSFHDLSIWLGKVRSENTRKKKLEDQITEWESNQNIQNPVINQLRTELESEYKALINKKRIRQLQERPHAFDLRSAKGVQRYSLQLDESQSIILAKEESDPNSKVNKWPISNIKQVLIDKACSHYNQRKENTFYFSITMDSRDDARDDP++TYNFSCNHKKNYAVWIDGLNILMNKPPTSQEFKEDLLNLVRMEMKIRFLFLSKENIHHEAPALPTLPSNYDFCN
Sbjct:    1 MSIYQFAVTFENNSRHYKENFNKDIGPKDLINRFAKDFGLDYNSLDEYQLIVHIKEEAPFYLKDHNVQCLPRVYMMDLCPLPGKEVSDIKIQMTSKDPEVVKKALECLAKRLSVQEFVILCIGSGLHIDLFRLVEKVI----GNEELSVLTMKVFAEFIVYTNRKEDFEAEPEADERPYISWLNIKAETIRSTLDYCKTSQNFNGIDSSLKVLVRYVNQNDTLRDFIFKNLDSVFIFNLFEKLHKSINILRPLKCSIQISLISLINCSFASSRESKDKFIEKLNDYFGKDKFRGLKENIDLITRKLREFPSELPPAGCSVPSKEENDLKQELTKLQYFILLPVYWDFSDTNYDGPKINDLELFKQMLSGNDSDTDFQVFEKLGFQNPSSPSRDFTEPPGHLVFSCIKYLINNCDEIYHNFAKRVFNNIPLIKIAFSLVKILDRALQLTEIIDENMDGGLYLPILFHTCEIDNDLSKKFFYELFQKCFVVYAQSLIDLKFKVEDLELESYFLNQINEVLNCYPTSFHDLSIWLGKVRSENTRKKKLEDQITEWESNQNIQNPVINQLRTELESEYKALINKKRIRQLQERPHAFDLRSAKGVQRYSLQLDESQSIILAKEESDPNSKVNKWPISNIKQVLIDKACSHYNQRKENTFYFSITMDSRDDARDDPVKTYNFSCNHKKNYAVWIDGLNILMNKPPTSQEFKEDLLNLVRMEMKIRFLFLSKENIHHEAPALPTLPSNYDFCN 743          
BLAST of Engulfment and cell motility 3 vs. Planmine SMEST
Match: SMESG000039535.1 (SMESG000039535.1)

HSP 1 Score: 293.893 bits (751), Expect = 3.837e-95
Identity = 141/141 (100.00%), Postives = 141/141 (100.00%), Query Frame = 1
Query:   73 MSIYQFAVTFENNSRHYKENFNKDIGPKDLINRFAKDFGLDYNSLDEYQLIVHIKEEAPFYLKDHNVQCLPRVYMMDLCPLPGKEVSDIKIQMTSKDPEVVKKALECLAKRLSVQEFVILCIGSGLHIDLFRLVEKVMQIK 495
            MSIYQFAVTFENNSRHYKENFNKDIGPKDLINRFAKDFGLDYNSLDEYQLIVHIKEEAPFYLKDHNVQCLPRVYMMDLCPLPGKEVSDIKIQMTSKDPEVVKKALECLAKRLSVQEFVILCIGSGLHIDLFRLVEKVMQIK
Sbjct:    1 MSIYQFAVTFENNSRHYKENFNKDIGPKDLINRFAKDFGLDYNSLDEYQLIVHIKEEAPFYLKDHNVQCLPRVYMMDLCPLPGKEVSDIKIQMTSKDPEVVKKALECLAKRLSVQEFVILCIGSGLHIDLFRLVEKVMQIK 141          
The following BLAST results are available for this feature:
BLAST of Engulfment and cell motility 3 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ELMO21.833e-2527.88engulfment and cell motility 2 [Source:HGNC Symbol... [more]
ELMO22.426e-2527.88engulfment and cell motility 2 [Source:HGNC Symbol... [more]
ELMO22.503e-2527.62engulfment and cell motility 2 [Source:HGNC Symbol... [more]
ELMO22.503e-2527.62engulfment and cell motility 2 [Source:HGNC Symbol... [more]
ELMO11.097e-1925.38engulfment and cell motility 1 [Source:HGNC Symbol... [more]
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BLAST of Engulfment and cell motility 3 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Engulfment and cell motility 3 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 1
Match NameE-valueIdentityDescription
Ced-121.682e-2025.72gene:FBgn0032409 transcript:FBtr0080330[more]
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BLAST of Engulfment and cell motility 3 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
elmo18.136e-2226.58engulfment and cell motility 1 (ced-12 homolog, C.... [more]
elmo18.616e-2226.58engulfment and cell motility 1 (ced-12 homolog, C.... [more]
elmo19.724e-2226.58engulfment and cell motility 1 (ced-12 homolog, C.... [more]
elmo31.149e-1925.58engulfment and cell motility 3 [Source:ZFIN;Acc:ZD... [more]
elmo21.504e-1825.57engulfment and cell motility 2 [Source:ZFIN;Acc:ZD... [more]
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BLAST of Engulfment and cell motility 3 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
elmo21.226e-2227.25engulfment and cell motility 2 [Source:NCBI gene;A... [more]
elmo21.475e-2227.25engulfment and cell motility 2 [Source:NCBI gene;A... [more]
elmo21.516e-2227.25engulfment and cell motility 2 [Source:NCBI gene;A... [more]
elmo21.643e-2227.18engulfment and cell motility 2 [Source:NCBI gene;A... [more]
ELMO13.663e-2026.08engulfment and cell motility 1 [Source:NCBI gene;A... [more]
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BLAST of Engulfment and cell motility 3 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Elmo22.253e-2527.95engulfment and cell motility 2 [Source:MGI Symbol;... [more]
Elmo22.253e-2527.95engulfment and cell motility 2 [Source:MGI Symbol;... [more]
Elmo22.283e-2527.95engulfment and cell motility 2 [Source:MGI Symbol;... [more]
Elmo16.968e-2025.38engulfment and cell motility 1 [Source:MGI Symbol;... [more]
Elmo26.412e-1728.47engulfment and cell motility 2 [Source:MGI Symbol;... [more]
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BLAST of Engulfment and cell motility 3 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q5RCC1|ELMO2_PONAB9.749e-2527.62Engulfment and cell motility protein 2 OS=Pongo ab... [more]
sp|Q96JJ3|ELMO2_HUMAN1.202e-2427.62Engulfment and cell motility protein 2 OS=Homo sap... [more]
sp|Q8BHL5|ELMO2_MOUSE1.597e-2427.95Engulfment and cell motility protein 2 OS=Mus musc... [more]
sp|A4FUD6|ELMO2_BOVIN7.986e-2427.62Engulfment and cell motility protein 2 OS=Bos taur... [more]
sp|Q8BPU7|ELMO1_MOUSE4.874e-1925.38Engulfment and cell motility protein 1 OS=Mus musc... [more]
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BLAST of Engulfment and cell motility 3 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A2U3Y7Y57.430e-2427.95engulfment and cell motility protein 2 OS=Leptonyc... [more]
A0A3Q7WYS31.489e-2327.95engulfment and cell motility protein 2 isoform X2 ... [more]
A0A5E4B9V91.888e-2327.95ELMO domain-containing protein OS=Marmota monax OX... [more]
A0A3Q7PM883.101e-2327.88engulfment and cell motility protein 2 isoform X4 ... [more]
A0A2U3ZKJ73.130e-2327.88engulfment and cell motility protein 2 isoform X4 ... [more]
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BLAST of Engulfment and cell motility 3 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
elmo11.110e-2327.59engulfment and cell motility protein 1 [Source:NCB... [more]
elmo13.909e-2327.34engulfment and cell motility protein 1 [Source:NCB... [more]
elmo14.065e-2327.34engulfment and cell motility protein 1 [Source:NCB... [more]
elmo14.429e-2327.34engulfment and cell motility protein 1 [Source:NCB... [more]
elmo14.429e-2327.34engulfment and cell motility protein 1 [Source:NCB... [more]
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BLAST of Engulfment and cell motility 3 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 1
Match NameE-valueIdentityDescription
elmo12.829e-2226.55engulfment and cell motility 1 (ced-12 homolog, C.... [more]
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BLAST of Engulfment and cell motility 3 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Engulfment and cell motility 3 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 1
Match NameE-valueIdentityDescription
EDO354516.310e-1927.90Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Engulfment and cell motility 3 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
elmo13.883e-2227.09engulfment and cell motility protein 1 [Source:NCB... [more]
elmo13.888e-2227.09engulfment and cell motility protein 1 [Source:NCB... [more]
elmo27.808e-2226.17engulfment and cell motility protein 2 [Source:NCB... [more]
elmo34.331e-2125.32engulfment and cell motility protein 3 [Source:NCB... [more]
elmo35.578e-2125.26engulfment and cell motility protein 3 [Source:NCB... [more]
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BLAST of Engulfment and cell motility 3 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 3
Match NameE-valueIdentityDescription
SMESG000039535.10.000e+099.73SMESG000039535.1[more]
SMESG000039535.10.000e+099.06SMESG000039535.1[more]
SMESG000039535.13.837e-95100.00SMESG000039535.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30028347 ID=SMED30028347|Name=Engulfment and cell motility 3|organism=Schmidtea mediterranea sexual|type=transcript|length=2459bp
TACATTTAAATTTTATTCCTGAAATATATTTTCAATTATCTCATTTTTTT
GAAATTTTAAATAATTTTGAATATGTCAATTTATCAGTTTGCTGTAACTT
TTGAAAATAATTCTCGTCATTACAAAGAAAATTTTAATAAGGATATTGGA
CCCAAAGACCTTATTAACAGATTTGCCAAAGATTTTGGGCTAGATTATAA
TTCCTTGGATGAATATCAGTTGATTGTGCACATTAAGGAGGAAGCCCCGT
TTTACTTGAAAGATCATAATGTTCAGTGTTTACCAAGAGTTTACATGATG
GACTTGTGTCCTTTGCCTGGAAAAGAAGTAAGTGATATTAAGATTCAAAT
GACTTCCAAAGACCCGGAAGTAGTTAAAAAGGCATTGGAATGCTTAGCTA
AACGATTATCTGTACAGGAATTCGTAATATTATGCATAGGAAGTGGTTTG
CATATTGACCTATTTCGATTGGTTGAAAAAGTTATGCAAATTAAAAATGG
GAATGAAGAATTGTCGGTTTTAACAATGAAAGTATTTGCAGAATTCATTG
TTTACACCAACAGAAAAGAAGATTTCGAGGCAGAACCAGAAGCCGATGAA
CGGCCATATATTTCGTGGTTGAATATAAAAGCTGAAACAATAAGATCGAC
TCTCGATTATTGTAAAACATCTCAAAATTTCAACGGAATAGATTCGTCTT
TGAAAGTTCTAGTGAGATATGTGAATCAAAATGATACACTCAGAGATTTT
ATTTTTAAAAATTTGGATTCAGTATTTATATTTAATTTATTTGAAAAATT
GCATAAAAGTATAAACATCTTACGGCCACTTAAATGTTCAATACAAATAT
CTCTTATTAGTCTTATTAATTGTTCTTTTGCCAGTAGCCGTGAATCAAAA
GATAAATTTATTGAAAAACTAAACGATTATTTTGGGAAAGACAAATTTCG
TGGCCTCAAAGAAAATATCGATCTTATCACCCGAAAACTAAGAGAATTCC
CATCAGAATTACCTCCGGCAGGTTGTAGCGTACCTTCGAAAGAGGAAAAT
GATTTAAAGCAGGAGCTTACAAAATTACAATACTTTATTTTGCTACCGGT
TTATTGGGATTTCAGTGATACGAATTATGATGGGCCAAAAATAAATGATT
TGGAATTATTCAAGCAAATGCTCTCGGGTAACGATTCCGACACTGATTTC
CAGGTATTTGAGAAATTGGGATTTCAAAATCCTTCGTCACCATCGAGAGA
CTTTACCGAGCCACCTGGGCATTTAGTTTTCAGTTGCATCAAATATTTAA
TTAATAATTGTGATGAAATTTACCATAATTTTGCTAAACGAGTTTTCAAT
AACATTCCATTGATAAAAATTGCATTTTCTTTAGTTAAAATATTGGATCG
TGCTCTGCAATTAACTGAAATTATTGATGAAAACATGGATGGCGGATTGT
ATTTACCGATTCTTTTTCATACATGCGAAATCGATAATGACTTATCGAAG
AAGTTTTTCTATGAACTCTTTCAGAAATGTTTTGTGGTATATGCTCAATC
TTTAATAGATTTGAAATTTAAAGTTGAAGATTTAGAATTGGAAAGTTATT
TTTTAAATCAAATAAATGAAGTTCTCAACTGTTACCCAACATCATTTCAC
GATCTTTCGATATGGTTAGGAAAGGTTCGGTCTGAAAATACAAGAAAGAA
AAAATTAGAAGATCAAATAACTGAATGGGAATCCAATCAGAATATTCAAA
ATCCGGTTATTAACCAATTAAGAACTGAACTGGAAAGCGAATATAAAGCA
CTTATCAATAAAAAAAGAATACGCCAATTGCAAGAAAGGCCCCATGCGTT
TGATTTGAGATCTGCAAAAGGCGTCCAAAGATACTCTTTACAATTAGATG
AGTCGCAGAGTATAATTCTAGCAAAAGAAGAATCAGATCCAAATTCTAAA
GTAAATAAATGGCCAATTTCTAACATTAAACAAGTTCTAATTGACAAAGC
GTGTTCTCATTACAACCAGCGAAAGGAAAACACGTTTTATTTTTCGATTA
CGATGGATTCTAGAGATGATGCTAGAGATGATCCAATAAGAACATATAAT
TTCTCATGTAATCATAAAAAGAACTATGCAGTATGGATCGATGGGTTAAA
CATTTTGATGAATAAACCTCCTACCTCTCAAGAATTTAAAGAGGATCTGC
TTAATTTAGTACGAATGGAAATGAAAATAAGATTTCTATTCCTTAGCAAA
GAGAACATCCATCATGAAGCACCTGCATTGCCAACTTTACCAAGCAATTA
TGATTTTTGCAATTGAAAGTTGAGTATATAAATCAACTTGTAATATTTAT
TTGATTTAGAATTTTATACTTTTTAAAATGATTGTATTATAATGATTGTA
TTCCACATTTTTAACATTTTATAAATATGATCTACATTTTTATTGAACTT
ATATTGTGA
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protein sequence of SMED30028347-orf-1

>SMED30028347-orf-1 ID=SMED30028347-orf-1|Name=SMED30028347-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=748bp
MSIYQFAVTFENNSRHYKENFNKDIGPKDLINRFAKDFGLDYNSLDEYQL
IVHIKEEAPFYLKDHNVQCLPRVYMMDLCPLPGKEVSDIKIQMTSKDPEV
VKKALECLAKRLSVQEFVILCIGSGLHIDLFRLVEKVMQIKNGNEELSVL
TMKVFAEFIVYTNRKEDFEAEPEADERPYISWLNIKAETIRSTLDYCKTS
QNFNGIDSSLKVLVRYVNQNDTLRDFIFKNLDSVFIFNLFEKLHKSINIL
RPLKCSIQISLISLINCSFASSRESKDKFIEKLNDYFGKDKFRGLKENID
LITRKLREFPSELPPAGCSVPSKEENDLKQELTKLQYFILLPVYWDFSDT
NYDGPKINDLELFKQMLSGNDSDTDFQVFEKLGFQNPSSPSRDFTEPPGH
LVFSCIKYLINNCDEIYHNFAKRVFNNIPLIKIAFSLVKILDRALQLTEI
IDENMDGGLYLPILFHTCEIDNDLSKKFFYELFQKCFVVYAQSLIDLKFK
VEDLELESYFLNQINEVLNCYPTSFHDLSIWLGKVRSENTRKKKLEDQIT
EWESNQNIQNPVINQLRTELESEYKALINKKRIRQLQERPHAFDLRSAKG
VQRYSLQLDESQSIILAKEESDPNSKVNKWPISNIKQVLIDKACSHYNQR
KENTFYFSITMDSRDDARDDPIRTYNFSCNHKKNYAVWIDGLNILMNKPP
TSQEFKEDLLNLVRMEMKIRFLFLSKENIHHEAPALPTLPSNYDFCN*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000016pharynx
PLANA:0000026gut
PLANA:0000034epidermis
PLANA:0000070intestinal phagocyte
PLANA:0003116parenchymal cell
Vocabulary: INTERPRO
TermDefinition
IPR030719ELMO3
IPR011993PH-like_dom_sf
Vocabulary: cellular component
TermDefinition
GO:0005737cytoplasm
GO:0005829cytosol
GO:0016020membrane
Vocabulary: biological process
TermDefinition
GO:0006909phagocytosis
GO:0006915apoptotic process
GO:0007010cytoskeleton organization
GO:0016477cell migration
GO:0060326cell chemotaxis
GO:0098609cell-cell adhesion
Vocabulary: molecular function
TermDefinition
GO:0017124SH3 domain binding
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
NoneNo IPR availableCOILSCoilCoilcoord: 535..555
NoneNo IPR availableGENE3DG3DSA:1.10.8.920coord: 563..746
e-value: 5.7E-27
score: 97.0
NoneNo IPR availablePANTHERPTHR12771ENGULFMENT AND CELL MOTILITYcoord: 378..746
NoneNo IPR availableSUPERFAMILYSSF50729PH domain-likecoord: 586..696
IPR011993PH-like domain superfamilyGENE3DG3DSA:2.30.29.30coord: 590..698
e-value: 5.7E-27
score: 97.0
IPR030719Engulfment and cell motility protein 3PANTHERPTHR12771:SF16ENGULFMENT AND CELL MOTILITY PROTEIN 3coord: 378..746