Protocadherin alpha-2
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30028328 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 8
Homology
BLAST of Protocadherin alpha-2 vs. Ensembl Human
Match: PCDH11X (protocadherin 11 X-linked [Source:HGNC Symbol;Acc:HGNC:8656]) HSP 1 Score: 253.062 bits (645), Expect = 7.977e-69 Identity = 225/678 (33.19%), Postives = 331/678 (48.82%), Query Frame = 2
Query: 299 DSGEIRITKVFDRDDVNNVCGPLGCCDKPSCEIVLDIIVTVIPKNERIPVKVVIVIEDENDNAPDXXXXXXXXXXXXNDATQLDHNLPKALDKDCPIYGIKNYSLSGNKVEYFSLKIRQF-----QPFLSVKKSFDFENPSEKQFNLSLNAIDNGG---KSATLQLIVNVIDINDNPPIFQKKIVNVTIQENTTFPDAILKLNATDLDSGNNAQISYKFSSINRPIIRETFQLQSETGKIYLLKTLDYELYSEQNFDINVLAIDHGSPQLSDSCIIKVNVTDINDNSPVIEI-----------VHSQPIPENEQITDPALKLYVSDYDSIDND-VKCQAE-KIGRRLKLEQVEKSSYFIYATEIYDYEKEKNLSLSILCQDSGKEPRYTKQLLTIFIKDVNDNRPKFLRSFYRKSINEDQEKLKPFTKVQALDKDSDDFGKVKYSIGLKDRKYFSIDEISGEVRLANEIDRETKDFYNVSVIATDGG--GLKDYSYIEISILDVNDNYPKLKSGS-SMRVNENLPVGSVVGYISVIDLDLGDNSKVEWTYDFLGNSSSMLQIENCTVYTSTVLDRESIEHLHILITMVDMGYPRLTSSATITVSVIDENDNIPKVIYPKTGSLVEEREMDHIAVNSPKYTTVLSIKSFDPDLGINGDVLYHILPSNGSQYFIINQTSG 2260
D+GEI T R D +C G C ++ V ++P VK+ +IED NDNAP F + ISI EN A + LP A+D D I G++NY L ++ F L + + P L V+K D E EK + +++GG +S+T L V+V D NDN P+F++ + V+I EN ++ +L+ATD D G NA+I + FS++ I R F L + TG I + + LD E N + VLA D G + ++ VNVTD+NDN P I+I V S+ IP N +I AL + V+D D+ N V C + +I RL+ V + + + DYE K ++ +L D+GK P +L I +KD NDN P F +SF SI E+ TKV A+D DS K+ Y +G FS+D +G + + ++DRE +D Y +++A D G L + +SI+D NDN P + V ENLP VG I+V D D GDNS V + N + + + + DRE E + D G +SSA +T++V+D NDN P I P + E + ++ T V + + D D G+N +V Y I+ N F I+Q +G
Sbjct: 80 DTGEIFTTGA--RIDREKLCA--GIPRDEHC--FYEVEVAILPDEIFRLVKIRFLIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGINGVQNYELIKSQ-NIFGLDVIETPEGDKMPQLIVQKELDRE---EKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATTGLITIKEPLDRE--ETPNHKLLVLASDGG--LMPARAMVLVNVTDVNDNVPSIDIRYIVNPVNDTVVLSENIPLNTKI---AL-ITVTDKDADHNGRVTCFTDHEIPFRLR--PVFSNQFLLETAAYLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQLTKVSAMDADSGPNAKINYLLGPDAPPEFSLDCRTGMLTVVKKLDREKEDKYLFTILAKDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYNFYVPENLPRHGTVGLITVTDPDYGDNSAVTLSI-LDENDDFTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSSAKVTINVVDVNDNKPVFIVPPSNCSYE-----LVLPSTNPGTVVFQVIAVDNDTGMNAEVRYSIVGGNTRDLFAIDQETG 731
BLAST of Protocadherin alpha-2 vs. Ensembl Human
Match: PCDH11X (protocadherin 11 X-linked [Source:HGNC Symbol;Acc:HGNC:8656]) HSP 1 Score: 253.062 bits (645), Expect = 2.359e-68 Identity = 225/678 (33.19%), Postives = 331/678 (48.82%), Query Frame = 2
Query: 299 DSGEIRITKVFDRDDVNNVCGPLGCCDKPSCEIVLDIIVTVIPKNERIPVKVVIVIEDENDNAPDXXXXXXXXXXXXNDATQLDHNLPKALDKDCPIYGIKNYSLSGNKVEYFSLKIRQF-----QPFLSVKKSFDFENPSEKQFNLSLNAIDNGG---KSATLQLIVNVIDINDNPPIFQKKIVNVTIQENTTFPDAILKLNATDLDSGNNAQISYKFSSINRPIIRETFQLQSETGKIYLLKTLDYELYSEQNFDINVLAIDHGSPQLSDSCIIKVNVTDINDNSPVIEI-----------VHSQPIPENEQITDPALKLYVSDYDSIDND-VKCQAE-KIGRRLKLEQVEKSSYFIYATEIYDYEKEKNLSLSILCQDSGKEPRYTKQLLTIFIKDVNDNRPKFLRSFYRKSINEDQEKLKPFTKVQALDKDSDDFGKVKYSIGLKDRKYFSIDEISGEVRLANEIDRETKDFYNVSVIATDGG--GLKDYSYIEISILDVNDNYPKLKSGS-SMRVNENLPVGSVVGYISVIDLDLGDNSKVEWTYDFLGNSSSMLQIENCTVYTSTVLDRESIEHLHILITMVDMGYPRLTSSATITVSVIDENDNIPKVIYPKTGSLVEEREMDHIAVNSPKYTTVLSIKSFDPDLGINGDVLYHILPSNGSQYFIINQTSG 2260
D+GEI T R D +C G C ++ V ++P VK+ +IED NDNAP F + ISI EN A + LP A+D D I G++NY L ++ F L + + P L V+K D E EK + +++GG +S+T L V+V D NDN P+F++ + V+I EN ++ +L+ATD D G NA+I + FS++ I R F L + TG I + + LD E N + VLA D G + ++ VNVTD+NDN P I+I V S+ IP N +I AL + V+D D+ N V C + +I RL+ V + + + DYE K ++ +L D+GK P +L I +KD NDN P F +SF SI E+ TKV A+D DS K+ Y +G FS+D +G + + ++DRE +D Y +++A D G L + +SI+D NDN P + V ENLP VG I+V D D GDNS V + N + + + + DRE E + D G +SSA +T++V+D NDN P I P + E + ++ T V + + D D G+N +V Y I+ N F I+Q +G
Sbjct: 80 DTGEIFTTGA--RIDREKLCA--GIPRDEHC--FYEVEVAILPDEIFRLVKIRFLIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGINGVQNYELIKSQ-NIFGLDVIETPEGDKMPQLIVQKELDRE---EKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATTGLITIKEPLDRE--ETPNHKLLVLASDGG--LMPARAMVLVNVTDVNDNVPSIDIRYIVNPVNDTVVLSENIPLNTKI---AL-ITVTDKDADHNGRVTCFTDHEIPFRLR--PVFSNQFLLETAAYLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQLTKVSAMDADSGPNAKINYLLGPDAPPEFSLDCRTGMLTVVKKLDREKEDKYLFTILAKDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYNFYVPENLPRHGTVGLITVTDPDYGDNSAVTLSI-LDENDDFTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSSAKVTINVVDVNDNKPVFIVPPSNCSYE-----LVLPSTNPGTVVFQVIAVDNDTGMNAEVRYSIVGGNTRDLFAIDQETG 731
BLAST of Protocadherin alpha-2 vs. Ensembl Human
Match: PCDH11X (protocadherin 11 X-linked [Source:HGNC Symbol;Acc:HGNC:8656]) HSP 1 Score: 253.062 bits (645), Expect = 2.471e-68 Identity = 227/679 (33.43%), Postives = 332/679 (48.90%), Query Frame = 2
Query: 299 DSGEIRITKVFDRDDVNNVCGPLGCCDKPSCEIVLDIIVTVIPKNERIPVKVVIVIEDENDNAPDXXXXXXXXXXXXNDATQLDHNLPKALDKDCPIYGIKNYSLSGNKVEYFSLKIRQF-----QPFLSVKKSFDFENPSEKQFNLSLNAIDNGG---KSATLQLIVNVIDINDNPPIFQKKIVNVTIQENTTFPDAILKLNATDLDSGNNAQISYKFSSINRPIIRETFQLQSETGKIYLLKTLDYELYSEQNFDINVLAIDHGSPQLSDSCIIKVNVTDINDNSPVIEI-----------VHSQPIPENEQITDPALKLYVSDYDSIDND-VKCQAE-KIGRRLKLEQVEKSSYFIYATEIYDYEKEKNLSLSILCQDSGKEPRYTKQLLTIFIKDVNDNRPKFLRSFYRKSINEDQEKLKPFTKVQALDKDSDDFGKVKYSIGLKDRKYFSIDEISGEVRLANEIDRETKDFYNVSVIATDGG--GLKDYSYIEISILDVNDNYPKLKSGS-SMRVNENLPVGSVVGYISVIDLDLGDNSKVEWTYDFLG-NSSSMLQIENCTVYTSTVLDRESIEHLHILITMVDMGYPRLTSSATITVSVIDENDNIPKVIYPKTGSLVEEREMDHIAVNSPKYTTVLSIKSFDPDLGINGDVLYHILPSNGSQYFIINQTSG 2260
D+GEI T R D +C G C ++ V ++P VK+ +IED NDNAP F + ISI EN A + LP A+D D I G++NY L ++ F L + + P L V+K D E EK + +++GG +S+T L V+V D NDN P+F++ + V+I EN ++ +L+ATD D G NA+I + FS++ I R F L + TG I + + LD E N + VLA D G + ++ VNVTD+NDN P I+I V S+ IP N +I AL + V+D D+ N V C + +I RL+ V + + + DYE K ++ +L D+GK P +L I +KD NDN P F +SF SI E+ TKV A+D DS K+ Y +G FS+D +G + + ++DRE +D Y +++A D G L + +SI+D NDN P + V ENLP VG I+V D D GDNS V T L N + + + + DRE E + D G +SSA +T++V+D NDN P I P + E + ++ T V + + D D G+N +V Y I+ N F I+Q +G
Sbjct: 80 DTGEIFTTGA--RIDREKLCA--GIPRDEHC--FYEVEVAILPDEIFRLVKIRFLIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGINGVQNYELIKSQ-NIFGLDVIETPEGDKMPQLIVQKELDRE---EKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATTGLITIKEPLDRE--ETPNHKLLVLASDGG--LMPARAMVLVNVTDVNDNVPSIDIRYIVNPVNDTVVLSENIPLNTKI---AL-ITVTDKDADHNGRVTCFTDHEIPFRLR--PVFSNQFLLETAAYLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQLTKVSAMDADSGPNAKINYLLGPDAPPEFSLDCRTGMLTVVKKLDREKEDKYLFTILAKDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYNFYVPENLPRHGTVGLITVTDPDYGDNSAV--TLSILDENDDFTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSSAKVTINVVDVNDNKPVFIVPPSNCSYE-----LVLPSTNPGTVVFQVIAVDNDTGMNAEVRYSIVGGNTRDLFAIDQETG 731
BLAST of Protocadherin alpha-2 vs. Ensembl Human
Match: PCDH11X (protocadherin 11 X-linked [Source:HGNC Symbol;Acc:HGNC:8656]) HSP 1 Score: 253.062 bits (645), Expect = 2.641e-68 Identity = 227/679 (33.43%), Postives = 332/679 (48.90%), Query Frame = 2
Query: 299 DSGEIRITKVFDRDDVNNVCGPLGCCDKPSCEIVLDIIVTVIPKNERIPVKVVIVIEDENDNAPDXXXXXXXXXXXXNDATQLDHNLPKALDKDCPIYGIKNYSLSGNKVEYFSLKIRQF-----QPFLSVKKSFDFENPSEKQFNLSLNAIDNGG---KSATLQLIVNVIDINDNPPIFQKKIVNVTIQENTTFPDAILKLNATDLDSGNNAQISYKFSSINRPIIRETFQLQSETGKIYLLKTLDYELYSEQNFDINVLAIDHGSPQLSDSCIIKVNVTDINDNSPVIEI-----------VHSQPIPENEQITDPALKLYVSDYDSIDND-VKCQAE-KIGRRLKLEQVEKSSYFIYATEIYDYEKEKNLSLSILCQDSGKEPRYTKQLLTIFIKDVNDNRPKFLRSFYRKSINEDQEKLKPFTKVQALDKDSDDFGKVKYSIGLKDRKYFSIDEISGEVRLANEIDRETKDFYNVSVIATDGG--GLKDYSYIEISILDVNDNYPKLKSGS-SMRVNENLPVGSVVGYISVIDLDLGDNSKVEWTYDFLG-NSSSMLQIENCTVYTSTVLDRESIEHLHILITMVDMGYPRLTSSATITVSVIDENDNIPKVIYPKTGSLVEEREMDHIAVNSPKYTTVLSIKSFDPDLGINGDVLYHILPSNGSQYFIINQTSG 2260
D+GEI T R D +C G C ++ V ++P VK+ +IED NDNAP F + ISI EN A + LP A+D D I G++NY L ++ F L + + P L V+K D E EK + +++GG +S+T L V+V D NDN P+F++ + V+I EN ++ +L+ATD D G NA+I + FS++ I R F L + TG I + + LD E N + VLA D G + ++ VNVTD+NDN P I+I V S+ IP N +I AL + V+D D+ N V C + +I RL+ V + + + DYE K ++ +L D+GK P +L I +KD NDN P F +SF SI E+ TKV A+D DS K+ Y +G FS+D +G + + ++DRE +D Y +++A D G L + +SI+D NDN P + V ENLP VG I+V D D GDNS V T L N + + + + DRE E + D G +SSA +T++V+D NDN P I P + E + ++ T V + + D D G+N +V Y I+ N F I+Q +G
Sbjct: 80 DTGEIFTTGA--RIDREKLCA--GIPRDEHC--FYEVEVAILPDEIFRLVKIRFLIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGINGVQNYELIKSQ-NIFGLDVIETPEGDKMPQLIVQKELDRE---EKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATTGLITIKEPLDRE--ETPNHKLLVLASDGG--LMPARAMVLVNVTDVNDNVPSIDIRYIVNPVNDTVVLSENIPLNTKI---AL-ITVTDKDADHNGRVTCFTDHEIPFRLR--PVFSNQFLLETAAYLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQLTKVSAMDADSGPNAKINYLLGPDAPPEFSLDCRTGMLTVVKKLDREKEDKYLFTILAKDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYNFYVPENLPRHGTVGLITVTDPDYGDNSAV--TLSILDENDDFTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSSAKVTINVVDVNDNKPVFIVPPSNCSYE-----LVLPSTNPGTVVFQVIAVDNDTGMNAEVRYSIVGGNTRDLFAIDQETG 731
BLAST of Protocadherin alpha-2 vs. Ensembl Human
Match: PCDH11X (protocadherin 11 X-linked [Source:HGNC Symbol;Acc:HGNC:8656]) HSP 1 Score: 252.677 bits (644), Expect = 3.323e-68 Identity = 227/679 (33.43%), Postives = 332/679 (48.90%), Query Frame = 2
Query: 299 DSGEIRITKVFDRDDVNNVCGPLGCCDKPSCEIVLDIIVTVIPKNERIPVKVVIVIEDENDNAPDXXXXXXXXXXXXNDATQLDHNLPKALDKDCPIYGIKNYSLSGNKVEYFSLKIRQF-----QPFLSVKKSFDFENPSEKQFNLSLNAIDNGG---KSATLQLIVNVIDINDNPPIFQKKIVNVTIQENTTFPDAILKLNATDLDSGNNAQISYKFSSINRPIIRETFQLQSETGKIYLLKTLDYELYSEQNFDINVLAIDHGSPQLSDSCIIKVNVTDINDNSPVIEI-----------VHSQPIPENEQITDPALKLYVSDYDSIDND-VKCQAE-KIGRRLKLEQVEKSSYFIYATEIYDYEKEKNLSLSILCQDSGKEPRYTKQLLTIFIKDVNDNRPKFLRSFYRKSINEDQEKLKPFTKVQALDKDSDDFGKVKYSIGLKDRKYFSIDEISGEVRLANEIDRETKDFYNVSVIATDGG--GLKDYSYIEISILDVNDNYPKLKSGS-SMRVNENLPVGSVVGYISVIDLDLGDNSKVEWTYDFLG-NSSSMLQIENCTVYTSTVLDRESIEHLHILITMVDMGYPRLTSSATITVSVIDENDNIPKVIYPKTGSLVEEREMDHIAVNSPKYTTVLSIKSFDPDLGINGDVLYHILPSNGSQYFIINQTSG 2260
D+GEI T R D +C G C ++ V ++P VK+ +IED NDNAP F + ISI EN A + LP A+D D I G++NY L ++ F L + + P L V+K D E EK + +++GG +S+T L V+V D NDN P+F++ + V+I EN ++ +L+ATD D G NA+I + FS++ I R F L + TG I + + LD E N + VLA D G + ++ VNVTD+NDN P I+I V S+ IP N +I AL + V+D D+ N V C + +I RL+ V + + + DYE K ++ +L D+GK P +L I +KD NDN P F +SF SI E+ TKV A+D DS K+ Y +G FS+D +G + + ++DRE +D Y +++A D G L + +SI+D NDN P + V ENLP VG I+V D D GDNS V T L N + + + + DRE E + D G +SSA +T++V+D NDN P I P + E + ++ T V + + D D G+N +V Y I+ N F I+Q +G
Sbjct: 80 DTGEIFTTGA--RIDREKLCA--GIPRDEHC--FYEVEVAILPDEIFRLVKIRFLIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGINGVQNYELIKSQ-NIFGLDVIETPEGDKMPQLIVQKELDRE---EKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATTGLITIKEPLDRE--ETPNHKLLVLASDGG--LMPARAMVLVNVTDVNDNVPSIDIRYIVNPVNDTVVLSENIPLNTKI---AL-ITVTDKDADHNGRVTCFTDHEIPFRLR--PVFSNQFLLETAAYLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQLTKVSAMDADSGPNAKINYLLGPDAPPEFSLDCRTGMLTVVKKLDREKEDKYLFTILAKDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYNFYVPENLPRHGTVGLITVTDPDYGDNSAV--TLSILDENDDFTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSSAKVTINVVDVNDNKPVFIVPPSNCSYE-----LVLPSTNPGTVVFQVIAVDNDTGMNAEVRYSIVGGNTRDLFAIDQETG 731
BLAST of Protocadherin alpha-2 vs. Ensembl Celegans
Match: fmi-1 (FlaMIngo (Cadherin plus 7TM domain) homolog [Source:UniProtKB/TrEMBL;Acc:A0A0K3AUS4]) HSP 1 Score: 177.563 bits (449), Expect = 1.137e-44 Identity = 155/548 (28.28%), Postives = 260/548 (47.45%), Query Frame = 2
Query: 722 LSLNAIDNGG--KSATLQLIVNVIDINDNPPIFQKKIVNVTIQENTTFPDAILKLNATDLDSGNNAQISYKFSSINRPIIRETFQLQSETGKIYLLKTLDYELYSEQNFDINVL--AIDHGSPQLSDSCIIKVNVTDINDNSPVIEIVHSQ-PIPENEQITDPALKLYVSDYDSIDNDVKCQAEKIGRRLKLEQ---VEKSSYFIYATEIYDYEKEKNLSLSILCQDSGKEPRYTKQLLTIFIKDVNDNRPKFLRSFYRKSINEDQEKLKPFTKVQALDKDSDDFGKVKYSIGLKDRKYFSIDEISGE---VRLANEIDRETKDFYNVSVIATDGGGLKDYSYIEISILDVN-----DNYPKLKSGSSMRVNENLPVGSVVGYISVIDLDLGDNSKVEWTYDFLGNSSSMLQIENCT--VYTSTVLDRESIEHLHILITMVDMGYPRLTSSATITVSVIDENDNIPKVIYPKTGSLVEEREMDHIAVNSPKYTTVLSIKSFDPDLGINGDVLYHILPSNGS---QYFIINQTSGVLKTTWIYDTISFT 2302
L + A D G + +T + + V+D+NDN P+F NVTI EN T P I + ATD D G N ++ Y +S + + TG++ L + +D +N I + A D P LS + + +NV DIND++P + + EN I + ++Y D DS N + I ++ + +++ S I T++ D E SL + +D G T + + +KD+NDN P F + Y +I+E+ + ++A+D D D K+ Y I DR+ FSI +I + + ++ E+ R+ V + ATD GGL+ + + I DVN +++P S+++ E+ P+G V + D D GDN+++ ++ D SS +I+ + + S+ LDRE +++T D P L +S I V + D NDN P+ + + E + P T+ L + + D D+G NG V Y + S+ S Q F +++TSG L+ + D F
Sbjct: 343 LDVIASDKGTPKRESTAMVEITVVDVNDNAPVFASDSYNVTILENITIPAVIATVKATDEDFGTNGKVHYSMASSSG---IGGLTIDYSTGEVTLRERID-----AKNSPITAVIRAKDGAQPALSSTVPLTINVIDINDHAPTLIAAQKMITLEENVAIGEEVGRVYAIDEDSGPNGI------IKYSMEGSEDFIIDEDSGLIKTTKLLDRETTARYSLKVTARDMGTPSLNTSTTIAVVLKDINDNAPTFDKKEYNVTISEEMPRGSQIITLKAVDNDEDQ--KITYRIEEADREVFSILDIGDQGAILSVSGELKRQDHKV-RVEISATDQGGLQGRCVVNVFIDDVNSAPYFNDHP-----FSVKIPEHSPIGYPVITLKAEDHDRGDNARIVYSID----SSQFFRIDPSSGDISVSSDLDREDRATFSVIVTASDHASPPLNTSTQIEVILDDINDNSPQFTSSSYAATISE--------DIPVGTSFLQVSAIDADIGPNGIVDYFLNESSSSPSIQLFRLDRTSGTLRVSSKLDREQFA 856 HSP 2 Score: 174.866 bits (442), Expect = 8.078e-44 Identity = 188/648 (29.01%), Postives = 310/648 (47.84%), Query Frame = 2
Query: 395 IVLDIIVT--VIPKNERIPVKVVIVIEDENDNAPDXXXXXXXXXXXXNDATQLDHNLPKALDKDCPIYGIKNYSLSGNKVEYFSLKIRQFQPFLSVKKSFDFENPSEKQFNLSLNAIDNG--GKSATLQLIVNVIDINDNPPIFQKKIVNVTIQENTTFPDAILKLNATDLDSGNNAQISYKFSSINRPIIRETFQLQSETGKIYLLKTLDYELYSEQNFDINVLAIDHGSPQLSDSCIIKVNVTDINDNSPVIE-----IVHSQPIPENEQITDPALKLYVSDYDSIDNDVKCQAEKIGRRLK---------LEQVEKSSYFIYATEIYDYEKEKNLSLSILCQDSGKEPRYTKQLLTIFIKDVNDNRPKFLRSFYRKSINEDQEKLKPFTKVQALDKDSDDFGKVKYSIGLKDRKYFSIDEISGEVRLANEIDRETKDFYNVSVIATDGGG--LKDYSYIEISILDVNDNYPKLKSGS-SMRVNENLPVGSVVGYISVIDLDLGDNSKVEWTYDFLGNSSSMLQIE-------NCTVYTSTVLDRESIEHLHILITMVDMGYPRLTSSATITVSVIDENDNIPKVIYPKTGSLVEEREMD-HIAVNSPKYTTVLSIKSFDPDLGINGDVLYHILPSNGSQYFIINQ 2251
I LD+I + PK E + V I + D NDNAP F+ S+ ++I EN KA D+D G +YS++ + L I +++++ D +N + A D S+T+ L +NVIDIND+ P +T++EN + + ++ A D DSG N I Y E F + ++G I K LD E + + + V A D G+P L+ S I V + DINDN+P + + S+ +P QI LK ++DND + +KI R++ L+ ++ + + E+ + + + +S Q G + R ++ +FI DVN + P F + I E P ++A D D D ++ YSI ++F ID SG++ +++++DRE + ++V V A+D L + IE+ + D+NDN P+ S S + ++E++PVG+ +S ID D+G N V++ FL SSS I+ + T+ S+ LDRE + + I D G P L++++ IT+++ D NDN P E+ D +IA NSP +TV +I + D D G N D+ + I ++ F I +
Sbjct: 341 IRLDVIASDKGTPKRESTAM-VEITVVDVNDNAPVFASDSYNVTILENITIPAVIATVKATDEDFGTNGKVHYSMASSS-GIGGLTIDYSTGEVTLRERIDAKN---SPITAVIRAKDGAQPALSSTVPLTINVIDINDHAPTLIAAQKMITLEENVAIGEEVGRVYAIDEDSGPNGIIKYSMEG------SEDFIIDEDSGLIKTTKLLDRE--TTARYSLKVTARDMGTPSLNTSTTIAVVLKDINDNAPTFDKKEYNVTISEEMPRGSQII--TLK-------AVDND---EDQKITYRIEEADREVFSILDIGDQGAILSVSGELKRQDHKVRVEISATDQ-GGLQGRC---VVNVFIDDVN-SAPYFNDHPFSVKIPEHSPIGYPVITLKAEDHDRGDNARIVYSI--DSSQFFRIDPSSGDISVSSDLDREDRATFSVIVTASDHASPPLNTSTQIEVILDDINDNSPQFTSSSYAATISEDIPVGTSFLQVSAIDADIGPNGIVDY---FLNESSSSPSIQLFRLDRTSGTLRVSSKLDREQFAVIVLPIFARDRGTPSLSAASEITLTLSDVNDNAPTF---------EQLSYDLYIAENSPVGSTVGTIVARDADEGDNADISFRIFGGADAKLFDIEE 944 HSP 3 Score: 149.443 bits (376), Expect = 6.086e-36 Identity = 158/566 (27.92%), Postives = 249/566 (43.99%), Query Frame = 2
Query: 446 VKVVIVIEDENDNAPDXXXXXXXXXXXXNDATQLDHNLPKALDKDCPIYGIKNYSLSGNKVEYFSLKIRQFQPFLSVKKSFDFENPSEKQFNLSLNAIDNGGKSATLQLIVNVI--DINDNPPIFQKKIVNVTIQENTTFPDAILKLNATDLDSGNNAQISYKFSSINRPI-----IRETFQLQSETGKIYLLKTLDYELYSEQNFDINVLAIDHGSPQLSDSCIIKVNVTDINDNSPVIEIVHSQPIPENEQITDPALKLYVSDYDSIDNDVKCQAEKIGRRLKLEQ---VEKSSYFIYATEIYDYEKEKNLSLSILCQDSGKEPRYTKQLLTIFIKDVNDNRPKFLRSFYRKSINEDQEKLKPFTKVQALDKDSDDFGKVKYSIGLKDR----KYFSIDEISGEVRLANEIDRETKDFYNVSVIATDGG--GLKDYSYIEISILDVNDNYPKLKSGS-SMRVNENLPVGSVVGYISVIDLDLGDNSKVEWTYDFLGNSSSMLQIEN-------CTVYTSTVLDRESIEHLHILITMVDMGYPRLTSSATITVSVIDENDNIPKV 2071
V + I + D ND+AP + I++ EN A + A+D+D GI YS+ G++ I + + K D E + +++L + A D G S + V+ DINDN P F KK NVTI E I+ L A D D + +I+Y+ +R + I + + S +G+ LK D+++ E + A D G L C++ V + D+N + S IPE+ I P + L D+D DN +I + Q ++ SS I + D E S+ + D P T + + + D+NDN P+F S Y +I+ED F +V A+D D G V Y + + F +D SG +R+++++DRE + + A D G L S I +++ DVNDN P + S + + EN PVGS VG I D D GDN+ + + F G + + IE + T D E+ + G +L+S+ + + V D NDN P +
Sbjct: 463 VPLTINVIDINDHAPTLIAAQKMITLEENVAIGEEVGRVYAIDEDSGPNGIIKYSMEGSE----DFIIDEDSGLIKTTKLLDRETTA--RYSLKVTARDMGTPSLNTSTTIAVVLKDINDNAPTFDKKEYNVTISEEMPRGSQIITLKAVDND--EDQKITYRIEEADREVFSILDIGDQGAILSVSGE---LKRQDHKVRVE------ISATDQGG--LQGRCVVNVFIDDVNSAPYFNDHPFSVKIPEHSPIGYPVITLKAEDHDRGDN------ARIVYSIDSSQFFRIDPSSGDISVSSDLDREDRATFSVIVTASDHASPPLNTSTQIEVILDDINDNSPQFTSSSYAATISEDIPVGTSFLQVSAIDADIGPNGIVDYFLNESSSSPSIQLFRLDRTSGTLRVSSKLDREQFAVIVLPIFARDRGTPSLSAASEITLTLSDVNDNAPTFEQLSYDLYIAENSPVGSTVGTIVARDADEGDNADISFRI-FGGADAKLFDIEEDAEQNGVVRILTRAEFDYEAKANKFFFELQASSG--QLSSTVPVRIHVSDVNDNKPAL 1000 HSP 4 Score: 135.961 bits (341), Expect = 7.801e-32 Identity = 118/410 (28.78%), Postives = 190/410 (46.34%), Query Frame = 2
Query: 965 FQLQSETGKIYLLKTLDYELYSEQNFDINVLAIDHGSPQLSDSCIIKVNVTDINDNSPVIEI-VHSQPIPENEQITDPALKLYVSDYDSIDNDVKCQAEKIGRRLKLEQVEKSSYFIYATEIYDYEKEKNLSLSILCQDSGKEPRYTKQLLTIFIKDVNDNRPKFLRSFYRKSINEDQEKLKPFTKVQALDKDSDDFGKVKYSIGLKDR-KYFSIDEISGEVRLANEIDRETKDFYNVSVIATDGG--GLKDYSYIEISILDVNDNYPKLKSGSSM-RVNENLPVGSVVGYISVIDLDLGDNSKVEWTYDFLGNSSSMLQIENCTVYTSTVLDRESIEHLHILITMVDMGYPRLTSSATITVSVIDENDNIPKVIYPKTGSLVEEREMDHIAVNSPKYTTVLSIKSFDPD 2179
F L + +G+I L K++D E+ + + V A + P +S S + V+V D+ DNSP+ E + I E+ I L ++ D DS +N + G L + S I D E + L ++ D G R + ++ I + DVNDN P F Y +I E+ V+A D+D GKV YS+ +ID +GEV L ID + V + A DG L + I+++D+ND+ P L + M + EN+ +G VG + ID D G N ++ Y G+ ++ ++ + T+ +LDRE+ + +T DMG P L +S TI V + D NDN P + + E EM P+ + ++++K+ D D
Sbjct: 213 FTLDTMSGEIRLAKSMDREVLDKHI--LKVTAYERVDPTISASTTVVVHVLDVQDNSPIFEKDSYFGEIREDAPIGTTVLSVFARDLDSGENGEIEYSLGEGNGKNLLAINAKSGVIQTAAPLDRETLSLIRLDVIASDKGTPKRESTAMVEITVVDVNDNAPVFASDSYNVTILENITIPAVIATVKATDEDFGTNGKVHYSMASSSGIGGLTIDYSTGEVTLRERIDAKNSPITAV-IRAKDGAQPALSSTVPLTINVIDINDHAPTLIAAQKMITLEENVAIGEEVGRVYAIDEDSGPNGIIK--YSMEGSEDFIIDEDSGLIKTTKLLDRETTARYSLKVTARDMGTPSLNTSTTIAVVLKDINDNAPTFDKKEYNVTISE-EM-------PRGSQIITLKAVDND 609 HSP 5 Score: 131.339 bits (329), Expect = 2.173e-30 Identity = 144/520 (27.69%), Postives = 239/520 (45.96%), Query Frame = 2
Query: 755 SATLQLIVNVIDINDNPPIFQKKIVNVTIQENTTFPDAILKLNATDLDSGNNAQISYKFSSINRPIIRETFQLQSETGKIYLLKTLDYELYSEQNFDINVLAIDHGSPQLSDSCIIKVNVTDINDNSPVIEIVHSQPIPENEQITDPALKLYVSDYDSIDNDVKCQAEKIGRRLKLEQVEKSSYFIYATEIYDYEKEKNLSLSILCQDS----------GKEPRYTKQL-LTIFIKDVNDNRPKFLRSFYRKSINEDQEKLKPFTKVQALDKDSDDFGKVKYSI-GLKDRKYFSIDEISGEVRLANEIDRETKDFYNVSVIATDGG--GLKDYSYIEISILDVNDNYPKL-KSGSSMRVNENLPVGSVVGYISVIDLDLGDNSKVEWTYDFLGNSS-SMLQI--ENCTVYTSTVLDRESIEHLHILITMVDMGYPRLTSSATITVSVIDENDNIPKVIYPKTGSLVEEREMDHIAVNSPKYTTVLSIKSFDPDLGINGDVLYHILPSNGSQYFIINQTSG 2260
SA+ ++V+V+D+ DN PIF+K I+E+ +L + A DLDSG N +I Y N + + +++G I LD E S D V+A D G+P+ + ++++ V D+NDN+PV S + E IT PA+ V D E G K+ SS I I E L I ++S G +P + + LTI + D+ND+ P + + ++ E+ + +V A+D+DS G +KYS+ G +D F IDE SG ++ +DRET Y++ V A D G L + I + + D+NDN P K ++ ++E +P GS + + +D D ++ K+ + + S+L I + + S L R+ + + I+ D G L + V + D N +P + + E +SP V+++K+ D D G N ++Y I + SQ+F I+ +SG
Sbjct: 251 SASTTVVVHVLDVQDNSPIFEKDSYFGEIREDAPIGTTVLSVFARDLDSGENGEIEYSLGEGNG---KNLLAINAKSGVIQTAAPLDRETLSLIRLD--VIASDKGTPKRESTAMVEITVVDVNDNAPVFA-SDSYNVTILENITIPAVIATVKATD----------EDFGTNGKVHYSMASSSGIGGLTIDYSTGEVTLRERIDAKNSPITAVIRAKDGAQPALSSTVPLTINVIDINDHAPTLIAAQKMITLEENVAIGEEVGRVYAIDEDSGPNGIIKYSMEGSED---FIIDEDSGLIKTTKLLDRETTARYSLKVTARDMGTPSLNTSTTIAVVLKDINDNAPTFDKKEYNVTISEEMPRGSQIITLKAVDND--EDQKITYRIEEADREVFSILDIGDQGAILSVSGELKRQD-HKVRVEISATDQG--GLQGRCVVNVFIDDVNSAPYFNDHPFSVKIPE---------HSPIGYPVITLKAEDHDRGDNARIVYSI---DSSQFFRIDPSSG 734 HSP 6 Score: 95.9005 bits (237), Expect = 1.297e-19 Identity = 64/232 (27.59%), Postives = 122/232 (52.59%), Query Frame = 2
Query: 1580 KDRKYFSIDEISGEVRLANEIDRETKDFYNVSVIATD--GGGLKDYSYIEISILDVNDNYPKLKSGSSM-RVNENLPVGSVVGYISVIDLDLGDNSKVEWTYDFLGNSSSMLQI--ENCTVYTSTVLDRESIEHLHILITMVDMGYPRLTSSATITVSVIDENDNIPKVIYPKTGSLVEEREMDHIAVNSPKYTTVLSIKSFDPDLGINGDVLYHILPSNGSQYFIINQTSG 2260
+ + F++D +SGE+RLA +DRE D + + V A + + + + + +LDV DN P + S + E+ P+G+ V + DLD G+N ++E++ GN ++L I ++ + T+ LDRE++ + + + D G P+ S+A + ++V+D NDN P + +++I + + + ++K+ D D G NG V Y + S+G I+ ++G
Sbjct: 208 RSQNLFTLDTMSGEIRLAKSMDREVLDKHILKVTAYERVDPTISASTTVVVHVLDVQDNSPIFEKDSYFGEIREDAPIGTTVLSVFARDLDSGENGEIEYSLG-EGNGKNLLAINAKSGVIQTAAPLDRETLSLIRLDVIASDKGTPKRESTAMVEITVVDVNDNAPVFASDSYNVTI----LENITIPA----VIATVKATDEDFGTNGKVHYSMASSSGIGGLTIDYSTG 430 HSP 7 Score: 65.855 bits (159), Expect = 1.780e-10 Identity = 84/308 (27.27%), Postives = 139/308 (45.13%), Query Frame = 2
Query: 278 NQYFRIS-DSGEIRITKVFDRDDVNNVCGPLGCCDKPSCEIVLDIIVTVI-----PKNERIPVKVVIVIEDENDNAPDXXXXXXXXXXXXNDATQLDHNLPKALDKDCPIYGIKNYSL----SGNKVEYFSLKIRQFQPFLSVKKSFDFENPSEKQFN---LSLNAIDNGGKS--ATLQLIVNVIDINDNPPIFQKKIVNVTIQENTTFPDAILKLNATDLDSGNNAQISYK-FSSINRPI--IRETFQLQSETGKIYLLKTLDYELYSEQNFDINVLAIDHGSPQLSDSCIIKVNVTDINDNSPVIE 1147
+Q+FRI SG+I ++ DR+D +IVT P N ++V++ +D NDN+P F+ SS+ +I E+ A+D D GI +Y L S ++ F L + L V D E QF L + A D G S A ++ + + D+NDN P F++ ++ I EN+ + + A D D G+NA IS++ F + + I E + Q+ +I DYE + + F + S QLS + ++++V+D+NDN P ++
Sbjct: 724 SQFFRIDPSSGDISVSSDLDRED----------------RATFSVIVTASDHASPPLNTSTQIEVIL--DDINDNSPQFTSSSYAATISEDIPVGTSFLQVSAIDADIGPNGIVDYFLNESSSSPSIQLFRLD--RTSGTLRVSSKLDRE-----QFAVIVLPIFARDRGTPSLSAASEITLTLSDVNDNAPTFEQLSYDLYIAENSPVGSTVGTIVARDADEGDNADISFRIFGGADAKLFDIEEDAE-QNGVVRILTRAEFDYEAKANKFF----FELQASSGQLSSTVPVRIHVSDVNDNKPALK 1001 HSP 8 Score: 57.3806 bits (137), Expect = 7.052e-8 Identity = 41/112 (36.61%), Postives = 61/112 (54.46%), Query Frame = 2
Query: 1943 LDRESIEHLHIL-ITMVDMGYPRLTSSATITVSVIDENDNIPKVIYPKTGSLVEEREMDHIAVNSPKYTTVLSIKSFDPDLGINGDVLYHILPSNGSQYFIINQTSGVLKTT 2275
+DRE ++ HIL +T + P +++S T+ V V+D DN P I+ K E RE ++P TTVLS+ + D D G NG++ Y + NG IN SGV++T
Sbjct: 228 MDREVLDK-HILKVTAYERVDPTISASTTVVVHVLDVQDNSP--IFEKDSYFGEIRE------DAPIGTTVLSVFARDLDSGENGEIEYSLGEGNGKNLLAINAKSGVIQTA 330
BLAST of Protocadherin alpha-2 vs. Ensembl Celegans
Match: fmi-1 (FlaMIngo (Cadherin plus 7TM domain) homolog [Source:UniProtKB/TrEMBL;Acc:A0A0K3AUS4]) HSP 1 Score: 176.792 bits (447), Expect = 2.255e-44 Identity = 150/528 (28.41%), Postives = 251/528 (47.54%), Query Frame = 2
Query: 776 VNVIDINDNPPIFQKKIVNVTIQENTTFPDAILKLNATDLDSGNNAQISYKFSSINRPIIRETFQLQSETGKIYLLKTLDYELYSEQNFDINVL--AIDHGSPQLSDSCIIKVNVTDINDNSPVIEIVHSQ-PIPENEQITDPALKLYVSDYDSIDNDVKCQAEKIGRRLKLEQ---VEKSSYFIYATEIYDYEKEKNLSLSILCQDSGKEPRYTKQLLTIFIKDVNDNRPKFLRSFYRKSINEDQEKLKPFTKVQALDKDSDDFGKVKYSIGLKDRKYFSIDEISGE---VRLANEIDRETKDFYNVSVIATDGGGLKDYSYIEISILDVN-----DNYPKLKSGSSMRVNENLPVGSVVGYISVIDLDLGDNSKVEWTYDFLGNSSSMLQIENCT--VYTSTVLDRESIEHLHILITMVDMGYPRLTSSATITVSVIDENDNIPKVIYPKTGSLVEEREMDHIAVNSPKYTTVLSIKSFDPDLGINGDVLYHILPSNGS---QYFIINQTSGVLKTTWIYDTISFT 2302
+ V+D+NDN P+F NVTI EN T P I + ATD D G N ++ Y +S + + TG++ L + +D +N I + A D P LS + + +NV DIND++P + + EN I + ++Y D DS N + I ++ + +++ S I T++ D E SL + +D G T + + +KD+NDN P F + Y +I+E+ + ++A+D D D K+ Y I DR+ FSI +I + + ++ E+ R+ V + ATD GGL+ + + I DVN +++P S+++ E+ P+G V + D D GDN+++ ++ D SS +I+ + + S+ LDRE +++T D P L +S I V + D NDN P+ + + E + P T+ L + + D D+G NG V Y + S+ S Q F +++TSG L+ + D F
Sbjct: 4 ITVVDVNDNAPVFASDSYNVTILENITIPAVIATVKATDEDFGTNGKVHYSMASSSGI---GGLTIDYSTGEVTLRERID-----AKNSPITAVIRAKDGAQPALSSTVPLTINVIDINDHAPTLIAAQKMITLEENVAIGEEVGRVYAIDEDSGPNGI------IKYSMEGSEDFIIDEDSGLIKTTKLLDRETTARYSLKVTARDMGTPSLNTSTTIAVVLKDINDNAPTFDKKEYNVTISEEMPRGSQIITLKAVDNDEDQ--KITYRIEEADREVFSILDIGDQGAILSVSGELKRQDHKV-RVEISATDQGGLQGRCVVNVFIDDVNSAPYFNDHP-----FSVKIPEHSPIGYPVITLKAEDHDRGDNARIVYSID----SSQFFRIDPSSGDISVSSDLDREDRATFSVIVTASDHASPPLNTSTQIEVILDDINDNSPQFTSSSYAATISE--------DIPVGTSFLQVSAIDADIGPNGIVDYFLNESSSSPSIQLFRLDRTSGTLRVSSKLDREQFA 497 HSP 2 Score: 172.17 bits (435), Expect = 5.454e-43 Identity = 181/627 (28.87%), Postives = 300/627 (47.85%), Query Frame = 2
Query: 452 VVIVIEDENDNAPDXXXXXXXXXXXXNDATQLDHNLPKALDKDCPIYGIKNYSLSGNKVEYFSLKIRQFQPFLSVKKSFDFENPSEKQFNLSLNAIDNG--GKSATLQLIVNVIDINDNPPIFQKKIVNVTIQENTTFPDAILKLNATDLDSGNNAQISYKFSSINRPIIRETFQLQSETGKIYLLKTLDYELYSEQNFDINVLAIDHGSPQLSDSCIIKVNVTDINDNSPVIE-----IVHSQPIPENEQITDPALKLYVSDYDSIDNDVKCQAEKIGRRLK---------LEQVEKSSYFIYATEIYDYEKEKNLSLSILCQDSGKEPRYTKQLLTIFIKDVNDNRPKFLRSFYRKSINEDQEKLKPFTKVQALDKDSDDFGKVKYSIGLKDRKYFSIDEISGEVRLANEIDRETKDFYNVSVIATDGGG--LKDYSYIEISILDVNDNYPKLKSGS-SMRVNENLPVGSVVGYISVIDLDLGDNSKVEWTYDFLGNSSSMLQIE-------NCTVYTSTVLDRESIEHLHILITMVDMGYPRLTSSATITVSVIDENDNIPKVIYPKTGSLVEEREMD-HIAVNSPKYTTVLSIKSFDPDLGINGDVLYHILPSNGSQYFIINQ 2251
V I + D NDNAP F+ S+ ++I EN KA D+D G +YS++ + L I +++++ D +N + A D S+T+ L +NVIDIND+ P +T++EN + + ++ A D DSG N I Y E F + ++G I K LD E + + + V A D G+P L+ S I V + DINDN+P + + S+ +P QI LK ++DND + +KI R++ L+ ++ + + E+ + + + +S Q G + R ++ +FI DVN + P F + I E P ++A D D D ++ YSI ++F ID SG++ +++++DRE + ++V V A+D L + IE+ + D+NDN P+ S S + ++E++PVG+ +S ID D+G N V++ FL SSS I+ + T+ S+ LDRE + + I D G P L++++ IT+++ D NDN P E+ D +IA NSP +TV +I + D D G N D+ + I ++ F I +
Sbjct: 2 VEITVVDVNDNAPVFASDSYNVTILENITIPAVIATVKATDEDFGTNGKVHYSMASSS-GIGGLTIDYSTGEVTLRERIDAKN---SPITAVIRAKDGAQPALSSTVPLTINVIDINDHAPTLIAAQKMITLEENVAIGEEVGRVYAIDEDSGPNGIIKYSMEG------SEDFIIDEDSGLIKTTKLLDRE--TTARYSLKVTARDMGTPSLNTSTTIAVVLKDINDNAPTFDKKEYNVTISEEMPRGSQII--TLK-------AVDND---EDQKITYRIEEADREVFSILDIGDQGAILSVSGELKRQDHKVRVEISATDQ-GGLQGRC---VVNVFIDDVN-SAPYFNDHPFSVKIPEHSPIGYPVITLKAEDHDRGDNARIVYSI--DSSQFFRIDPSSGDISVSSDLDREDRATFSVIVTASDHASPPLNTSTQIEVILDDINDNSPQFTSSSYAATISEDIPVGTSFLQVSAIDADIGPNGIVDY---FLNESSSSPSIQLFRLDRTSGTLRVSSKLDREQFAVIVLPIFARDRGTPSLSAASEITLTLSDVNDNAPT---------FEQLSYDLYIAENSPVGSTVGTIVARDADEGDNADISFRIFGGADAKLFDIEE 585 HSP 3 Score: 97.4413 bits (241), Expect = 4.480e-20 Identity = 79/261 (30.27%), Postives = 126/261 (48.28%), Query Frame = 2
Query: 1409 LLTIFIKDVNDNRPKFLRSFYRKSINEDQEKLKPFTKVQALDKDSDDFGKVKYSIGLKDR-KYFSIDEISGEVRLANEIDRETKDFYNVSVIATDGG--GLKDYSYIEISILDVNDNYPKLKSGSSM-RVNENLPVGSVVGYISVIDLDLGDNSKVEWTYDFLGNSSSMLQIENCTVYTSTVLDRESIEHLHILITMVDMGYPRLTSSATITVSVIDENDNIPKVIYPKTGSLVEEREMDHIAVNSPKYTTVLSIKSFDPD 2179
++ I + DVNDN P F Y +I E+ V+A D+D GKV YS+ +ID +GEV L ID + V + A DG L + I+++D+ND+ P L + M + EN+ +G VG + ID D G N ++ Y G+ ++ ++ + T+ +LDRE+ + +T DMG P L +S TI V + D NDN P + + E EM P+ + ++++K+ D D
Sbjct: 1 MVEITVVDVNDNAPVFASDSYNVTILENITIPAVIATVKATDEDFGTNGKVHYSMASSSGIGGLTIDYSTGEVTLRERIDAKNSPITAV-IRAKDGAQPALSSTVPLTINVIDINDHAPTLIAAQKMITLEENVAIGEEVGRVYAIDEDSGPNGIIK--YSMEGSEDFIIDEDSGLIKTTKLLDRETTARYSLKVTARDMGTPSLNTSTTIAVVLKDINDNAPTFDKKEYNVTISE-EM-------PRGSQIITLKAVDND 250 HSP 4 Score: 79.337 bits (194), Expect = 1.481e-14 Identity = 108/406 (26.60%), Postives = 182/406 (44.83%), Query Frame = 2
Query: 1097 IIKVNVTDINDNSPVIEIVHSQPIPENEQITDPALKLYVSDYDSIDNDVKCQAEKIGRRLKLEQVEKSSYFIYATEIYDYEKEKNLSLSILCQDS----------GKEPRYTKQL-LTIFIKDVNDNRPKFLRSFYRKSINEDQEKLKPFTKVQALDKDSDDFGKVKYSI-GLKDRKYFSIDEISGEVRLANEIDRETKDFYNVSVIATDGG--GLKDYSYIEISILDVNDNYPKL-KSGSSMRVNENLPVGSVVGYISVIDLDLGDNSKVEWTYDFLGNSS-SMLQI--ENCTVYTSTVLDRESIEHLHILITMVDMGYPRLTSSATITVSVIDENDNIPKVIYPKTGSLVEEREMDHIAVNSPKYTTVLSIKSFDPDLGINGDVLYHILPSNGSQYFIINQTSG 2260
++++ V D+NDN+PV S + E IT PA+ V D E G K+ SS I I E L I ++S G +P + + LTI + D+ND+ P + + ++ E+ + +V A+D+DS G +KYS+ G +D F IDE SG ++ +DRET Y++ V A D G L + I + + D+NDN P K ++ ++E +P GS + + +D D ++ K+ + + S+L I + + S L R+ + + I+ D G L + V + D N +P + + E +SP V+++K+ D D G N ++Y I + SQ+F I+ +SG
Sbjct: 1 MVEITVVDVNDNAPVFA-SDSYNVTILENITIPAVIATVKATD----------EDFGTNGKVHYSMASSSGIGGLTIDYSTGEVTLRERIDAKNSPITAVIRAKDGAQPALSSTVPLTINVIDINDHAPTLIAAQKMITLEENVAIGEEVGRVYAIDEDSGPNGIIKYSMEGSED---FIIDEDSGLIKTTKLLDRETTARYSLKVTARDMGTPSLNTSTTIAVVLKDINDNAPTFDKKEYNVTISEEMPRGSQIITLKAVDND--EDQKITYRIEEADREVFSILDIGDQGAILSVSGELKRQD-HKVRVEISATDQG--GLQGRCVVNVFIDDVNSAPYFNDHPFSVKIPE---------HSPIGYPVITLKAEDHDRGDNARIVYSI---DSSQFFRIDPSSG 375 HSP 5 Score: 70.4774 bits (171), Expect = 6.824e-12 Identity = 70/267 (26.22%), Postives = 115/267 (43.07%), Query Frame = 2
Query: 683 SFDFENPSEKQFNLSLNAIDNGGKSATLQLIVNVI--DINDNPPIFQKKIVNVTIQENTTFPDAILKLNATDLDSGNNAQISYKFSSINRPIIRETFQLQSETGKIYLLKTLDYELYSEQNFDINVLAIDHGSPQLSDSCIIKVNVTDINDNSPVIE-IVHSQPIPENEQITDPALKLYVSDYDSIDN-DVKCQAEKIGRRLKLEQVEKSS-----YFIYATEIYDYEKEKNLSLSILCQDSGKEPRYTKQLLTIFIKDVNDNRPKF 1456
S D + F++ + A D+ + VI DINDN P F TI E+ + L+++A D D G N + Y + + + F+L +G + + LD E ++ + + A D G+P LS + I + ++D+NDN+P E + + I EN + + D D DN D+ + G KL +E+ + I +DYE + N L SG+ + I + DVNDN+P
Sbjct: 380 SSDLDREDRATFSVIVTASDHASPPLNTSTQIEVILDDINDNSPQFTSSSYAATISEDIPVGTSFLQVSAIDADIGPNGIVDYFLNESSSSPSIQLFRLDRTSGTLRVSSKLDREQFAV--IVLPIFARDRGTPSLSAASEITLTLSDVNDNAPTFEQLSYDLYIAENSPVGSTVGTIVARDADEGDNADISFRIFG-GADAKLFDIEEDAEQNGVVRILTRAEFDYEAKANKFFFELQASSGQLSSTVP--VRIHVSDVNDNKPAL 641 HSP 6 Score: 66.2402 bits (160), Expect = 1.513e-10 Identity = 84/308 (27.27%), Postives = 139/308 (45.13%), Query Frame = 2
Query: 278 NQYFRIS-DSGEIRITKVFDRDDVNNVCGPLGCCDKPSCEIVLDIIVTVI-----PKNERIPVKVVIVIEDENDNAPDXXXXXXXXXXXXNDATQLDHNLPKALDKDCPIYGIKNYSL----SGNKVEYFSLKIRQFQPFLSVKKSFDFENPSEKQFN---LSLNAIDNGGKS--ATLQLIVNVIDINDNPPIFQKKIVNVTIQENTTFPDAILKLNATDLDSGNNAQISYK-FSSINRPI--IRETFQLQSETGKIYLLKTLDYELYSEQNFDINVLAIDHGSPQLSDSCIIKVNVTDINDNSPVIE 1147
+Q+FRI SG+I ++ DR+D +IVT P N ++V++ +D NDN+P F+ SS+ +I E+ A+D D GI +Y L S ++ F L + L V D E QF L + A D G S A ++ + + D+NDN P F++ ++ I EN+ + + A D D G+NA IS++ F + + I E + Q+ +I DYE + + F + S QLS + ++++V+D+NDN P ++
Sbjct: 365 SQFFRIDPSSGDISVSSDLDRED----------------RATFSVIVTASDHASPPLNTSTQIEVIL--DDINDNSPQFTSSSYAATISEDIPVGTSFLQVSAIDADIGPNGIVDYFLNESSSSPSIQLFRLD--RTSGTLRVSSKLDRE-----QFAVIVLPIFARDRGTPSLSAASEITLTLSDVNDNAPTFEQLSYDLYIAENSPVGSTVGTIVARDADEGDNADISFRIFGGADAKLFDIEEDAE-QNGVVRILTRAEFDYEAKANKFF----FELQASSGQLSSTVPVRIHVSDVNDNKPALK 642
BLAST of Protocadherin alpha-2 vs. Ensembl Celegans
Match: cdh-1 (CaDHerin family [Source:UniProtKB/TrEMBL;Acc:Q5F4W0]) HSP 1 Score: 172.555 bits (436), Expect = 4.958e-43 Identity = 169/591 (28.60%), Postives = 265/591 (44.84%), Query Frame = 2
Query: 581 CPIYGIKNYSLSGN--KVEYF------SLKIRQFQPFLSVKKSFDFENPSEKQFNLSLNAIDNGGKSATLQLIVNVIDINDNPPIFQKKIVNVTIQENTTFPDAILKLNATDLDSGNNAQISYKFSSINRPIIRETFQLQSETGKIYLLKTLDYELYSEQNFDINVLAIDHGSPQLSDSCIIKVNVTDINDNSPVI-----------EIVHSQPIPENEQITDPALKLYVSDYD---SIDNDVKCQAEKIGRRLKLEQVEKSSYFIYATEIYDYEKEKNLSLSILCQDSGKEPRYTKQLLTIFIKDVNDNRPKFLRSFYRKSINEDQEKLKPFTKVQALDKDSDDFGKVKYSI-GLKDRKYFSIDEISGEVRLANEIDRETKDFYNVSVIATDGGGLKDYSYIE--ISILDVNDNYPKL-KSGSSMRVNENLPVGSVVGYISVIDLDLGDNSKVEWTYDFLGNSSSMLQIEN--CTVYTSTVLDRESIEHLHILITMVDMGYPRLTSSATITVSVIDENDNIPKV--IYPKTGSLVEEREMDHIAVNSPKYTTVLSIKSFDPDLGINGDVLYH--------ILPSNGSQYF 2239
C + + N S GN ++ Y L + + ++K+FDFE +K + ++ A + +++T + + + D+NDN PIF ++T++E + +L ++A+D+DSG ++SY S + +F + TG+++ K L + F + V A D G +S I + V D + +P +I+ I ++ +Y D D SID D G+ IY T D + + L+I E T+ + IFI+D NDN P+F S SI ED + +PF VQA DKD G+V+YSI ID+ +G++ + +D E Y + V ATD G S + I +LDVNDN P+ KS +M V EN P ++VG + D D +N ++ + + N S I+ VYT +DRE I H+ I I D G P +S+A+ +SV+D NDN P I P + SP T + +I + DPD G+NG VLY ++ SNG Y
Sbjct: 558 CLVKVVANNSQCGNSKRIRYSLQNQDEHLTVDTMSGTVCIQKTFDFEK--QKSYQTTVIATNANSETSTSLISIRLKDVNDNWPIFYPNEYHLTVREGPKPEEPLLVVSASDMDSGTFGEVSYHILSES-----SSFSINPVTGEVFAQKPL-----ARGRFHLVVSAKDGGGQSSENSANIHITVIDKDTKTPQFSRSKYEIRTTEDILPGIAIGSVGAMSKVKYSIYSGDQDHNFSIDEDT-------GK-------------IYVTRYLDADVHDTVLLNIQATLPSGESNQTQ--VVIFIEDHNDNPPQFSSSLVEISIREDLKLHEPFYVVQASDKDKKKNGEVRYSIISSHPGSSIEIDQFTGQLSTGSLLDYEATRNYKLRVKATDLGIPPRSSNMTLFIHVLDVNDNAPEFEKSWYTMEVLENSPPKTIVGKVVARDKDSLENGQIVYR---ITNGSEYFGIDEKLGNVYTKRSIDREVISHVDISIVAEDKGVPPRSSTASARISVLDVNDNPPSCLSITPIV-----------VPAGSPLSTAIGTIVAMDPDKGLNGSVLYRAQLQSSLFVVKSNGDVYL 1100 HSP 2 Score: 140.969 bits (354), Expect = 2.366e-33 Identity = 167/625 (26.72%), Postives = 271/625 (43.36%), Query Frame = 2
Query: 446 VKVVIVIEDENDNAPDXXXXXXXXXXXXNDATQLDHNLPKALDKDCPIYGIKNYS-LSGNKVEYFSLKIR----QFQPFLSVKKSFDFENPSEKQFNLSLNAIDNG--GKSATLQLIVNVIDINDNPPIFQKKIVNVTIQENTTFPDAILKLNATDLDSGNNAQISYKFSSINRPIIRETFQLQSETGKIYLLKTLDYELYSEQNFDINVLAIDHGSPQLSDSCIIKVNVTDINDNSPVIEIV-----HSQPIPENEQITDPALKLYVSDYDSIDNDVKCQAEKIGRR-LKLEQVEKSS-YFIYATEIYDYEKEKNLSLSILCQDSGKEPRYTKQLLTIFIKDVNDNRPKFLRSFYRKSINEDQEKLKPFTKVQALDKDSDDFGKVKYSIGLKDRKYFSIDEISGEVRLANEIDRETKDFYNVSVIATDGG--GLKDYSYIEISILDVNDNYPKL-KSGSSMRVNENLPVGSVVGYISVIDLDLGDNSKVEWTYDFLGNSSSMLQIENC--TVYTSTVLDRESIEHLHILITMVDMGYPRLTSSATITVSVIDENDNIPKVIYPKTGSLVEEREMDHIAVNSPK-YTTVLSIKSFDPDLGINGDVLYHILPSNGSQYFIINQTSG 2260
+ +++ ++DENDNAP F++ + I E LP D D P + + + L GN F L R Q Q L V D E ++ L + A D G K L+ + +ID NDN P+F + ++ N + ++ + ATD D G N++ISY + P F + S++G I T L D+ V+A DHGSP LS S ++ + V +SP ++I+ +S + EN + ++ ++ D K + IG L +Q +++ Y + I D E L L + G+ QLLT I D+NDN P++ S S+N Q + T A D D G ++YS+ D + SID+ +G + + N ID V A DGG L + +LD P+ K+ + + E+ P+G+ + + + G++ ++ ++ L N L ++ TV D E + T++ TS++ I++ + D NDN P + YP E PK +L + + D D G G+V YHIL + S F IN +G
Sbjct: 106 IDILVEVDDENDNAPSFADQVVKLEISEFAQLGTSFALPTVTDGDGPKFDVHRFVILQGNVNNVFKLASRKVNEQLQADLVVNGQLDRE--FRDKYELLIEAQDGGKPAKIGQLRCSIEIIDANDNAPVFSRSRYTASVSANISIGSHLITVQATDADIGENSRISYDIKKTSAP-SNSNFAI-SQSGVI----TTTASLLPASTHDVIVVASDHGSPSLSSSAVVTITVLGSTLSSPPLDIIWLVESNSAHLMENSTLGSIVARVSIAQQ---YRDTKLRL--IGSSALCPQQTDQAHVYLLLLCGILDRETASEHHLKFLLEKDGQIIIEHPQLLT--IGDINDNAPQWHSSQIHISLNRTQGGSRTLT---AKDPDLGQNGWIRYSV--LDTELVSIDKETGRIFVPNTIDCNIGSEIKFRVRAEDGGSPALSTDLQVVADLLDTESKPPQFEKALWQVEIPEDTPIGTCLVKVVANNSQCGNSKRIRYS---LQNQDEHLTVDTMSGTVCIQKTFDFEKQKSYQ--TTVIATNANSETSTSLISIRLKDVNDNWP-IFYPN--------EYHLTVREGPKPEEPLLVVSASDMDSGTFGEVSYHILSESSS--FSINPVTG 694 HSP 3 Score: 127.487 bits (319), Expect = 3.227e-29 Identity = 124/448 (27.68%), Postives = 203/448 (45.31%), Query Frame = 2
Query: 704 SEKQFNLSLNAIDNGGKSA--TLQLIVNVIDINDNPPIFQKKIVNVTIQENTTFPDAILKLNATDLDSGNNAQISYKFSSINRPIIRETFQLQSETGKIYLLKTLDYELYSEQNFDINVLAIDHGSPQ-LSDSCIIKVNVTDINDNSP-----VIEIVHSQPIPENEQITDPALKLYVSDYDSIDN-DVKCQ--AEKIGRRLKLEQVEKSSYFIYATEIYDYEKEKNLSLSILCQDSGKEPRYTKQLLTIFIKDVNDNRPKFLRSFYRKSINEDQEKLKPFTKVQALDKDSDDFGKVKYSIGLKDRKYFSIDEISGEVRLANEIDRETKDFYNVSVIATDGG--GLKDYSYIEISILDVNDNYPKLKSGSSMRVNENLPVGSVVGYISVIDLDLGDNSKVEWTYDFLGNSSSMLQIENCTVYTSTVLDRESIEHLHILITMVDMGYPR 2008
+ +F+L ++A D GG+S+ + + + VID + P F + + E+ AI + A +++ Y S ++ F + +TGKIY+ + LD +++ D +L I P S+ + + + D NDN P ++EI I E+ ++ +P + SD D N +V+ + G ++++Q + + DYE +N L + D G PR + L I + DVNDN P+F +S+Y + E+ KV A DKDS + G++ Y I +YF IDE G V IDRE ++S++A D G + IS+LDVNDN P S + + V P+ + +G I +D D G N V + SS + N VY L+ H + + + D G PR
Sbjct: 703 ARGRFHLVVSAKDGGGQSSENSANIHITVIDKDTKTPQFSRSKYEIRTTEDILPGIAIGSVGAM-------SKVKYSIYSGDQ---DHNFSIDEDTGKIYVTRYLDADVH-----DTVLLNIQATLPSGESNQTQVVIFIEDHNDNPPQFSSSLVEI----SIREDLKLHEPFYVVQASDKDKKKNGEVRYSIISSHPGSSIEIDQFTGQ---LSTGSLLDYEATRNYKLRVKATDLGIPPRSSNMTLFIHVLDVNDNAPEFEKSWYTMEVLENSPPKTIVGKVVARDKDSLENGQIVYRI-TNGSEYFGIDEKLGNVYTKRSIDREVISHVDISIVAEDKGVPPRSSTASARISVLDVNDNPPSCLSITPIVVPAGSPLSTAIGTIVAMDPDKGLNGSVLYRAQL--QSSLFVVKSNGDVYLRRQLNASDERHQRLSVIVSDQGVPR 1125 HSP 4 Score: 98.9821 bits (245), Expect = 1.586e-20 Identity = 104/367 (28.34%), Postives = 173/367 (47.14%), Query Frame = 2
Query: 299 DSGEIRITKVFDRDDVNNVCGPLGCCDKPSCEIVLDIIVTVIPKNERIPVKVVIVIEDENDNAPDXXXXXXXXXXXXNDATQLDHNLPKALDKDCPIYGIKNYSLSGNKVEYFSLKIRQFQPFLSVKKSFDFENPSEKQFNLSLNAIDNG--GKSATLQLIVNVIDINDNPPIFQKKIVNVTIQENTTFPDAILKLNATDLDSGNNAQISYKFSSINRPIIRETFQLQSETGKIYLLKTLDYELYSEQNFDINVLAIDHGSPQLSDSCIIKVNVTDINDNSPVIEIVHSQPIPENEQITDPALKLYVSDYDSIDNDVKCQAEKIGRRLKLEQ---VEKSSYFIYATEIYDYEKEKNLSLSILCQDSG 1384
D+G+I +T+ D D + V +L+I T +P E +VVI IED NDN P FS S ISI E+ + +A DKD G YS+ + S++I QF LS D+E + + + L + A D G +S+ + L ++V+D+NDN P F+K + + EN+ + K+ A D DS N QI Y+ ++ + E F + + G +Y +++D E+ S + DI+++A D G P S + +++V D+NDN P + +P ++ + D D K + R +L+ V KS+ +Y + E++ LS++ D G
Sbjct: 787 DTGKIYVTRYLDADVHDTV--------------LLNIQAT-LPSGESNQTQVVIFIEDHNDNPPQFSSSLVEISIREDLKLHEPFYVVQASDKDKKKNGEVRYSIISSH-PGSSIEIDQFTGQLSTGSLLDYE--ATRNYKLRVKATDLGIPPRSSNMTLFIHVLDVNDNAPEFEKSWYTMEVLENSPPKTIVGKVVARDKDSLENGQIVYRITNGS-----EYFGIDEKLGNVYTKRSIDREVIS--HVDISIVAEDKGVPPRSSTASARISVLDVNDNPPSCLSITPIVVPAGSPLSTAIGTIVAMDPD------KGLNGSVLYRAQLQSSLFVVKSNGDVYLRRQLNASDERHQRLSVIVSDQG 1122 HSP 5 Score: 81.6481 bits (200), Expect = 2.758e-15 Identity = 138/538 (25.65%), Postives = 212/538 (39.41%), Query Frame = 2
Query: 758 ATLQLIVNVIDINDNPPIFQKKIVNVTIQENTTFPDAILKLNATDLDSGNNAQISYKFSSINRPIIRETFQLQSETGKIYLLKTLDYELYSEQNFDINVLAIDHGSPQLSDSCIIKVNVTDINDNSPVIEIVHSQP----IPENEQITDPALKLYVSDYDSIDND----------------VKCQAEKIGRRLKLEQVEKSSYFIYATEIYDYEKEKNLSLSIL-CQDSGKEPRYTKQLLTIFIKDVNDNRPKFLRSFYRKSINEDQEKLKPFTKVQALDKDSDDFGKVKYSI--GLKDRKYFSIDEISGEVRLANEIDRETKDFYNVSVIATDGGGLKDYSYIEISILDVNDNYPKLKSGSSMRVNENLPVGSVVGYISVIDLDLGDNSKVEWTYDFLGNSSSMLQIEN--CTVYTSTVLDRESIEHLHILITMVDMGYPRLTSSATITVSVIDENDNIPKVIYPKTGSLVEEREMDHIAVNSPKYTTVLSIKSFDP----------DLGINGDVLYHILPSNGSQYFIINQTSGVL 2266
+TL++ V + + P I VTI+EN D ++ AT G + ++F N P F + S TG I +L LD E + Q + ++ D GS +DSC ++V V D NDN P ++ S P I E+ ++ D + SD D N V + + RRL Q K + + EKNL +S Q K P +FL+ Y +I+E + + K+Q + + YSI G D FS+D G +R E+DRE + Y++ VI T G G + + +++ + ++NDN P RV ENL VGS V + D+D + D G + + I+ T++ + LD E + + I D + T+ +T+ V D NDN P + P Y T +S +F P DL G + Y L S F + SG L
Sbjct: 1615 STLKIHVEPV-FTEPPKISSTSCGVVTIEENVGIED-FKRILAT----GMTEESRFRFQG-NAP----KFSINSTTGSISVLP-LDRE--ASQEHLLIIILTDGGS--RNDSCTVRVTVADQNDNKPQLDA--STPSELEIAESSRVGDVLHRFRASDMDIGQNGKFSFELLEDSSGSLDLVPETGDLVLRRLSSLQSWKIKLRVVDHGVPGLYVEKNLEISNRNPQTEAKAPL------------------EFLKQTYLSTIDEGLPRGQFIAKLQP------ELAGLTYSIVEGNID-SAFSVDS-EGVIRTNLELDREILERYSLKVIGT-GSGQQIGTRVDVRVNNLNDNVPSFPMSKPRRVPENLRVGSYVATVGAKDVDNLAPLRYFLVSDSSGQTPTHFNIDQFTGTIHLTAPLDFEVLPEHTLTIKATDGSFDTFTN---LTIFVSDINDNAP-------------------TFSKPLYQTTVSPATFSPGQPFAKIEAHDLDARGALTYS-LGQGSSSIFRVAPESGAL 2084 HSP 6 Score: 77.0258 bits (188), Expect = 8.147e-14 Identity = 100/414 (24.15%), Postives = 182/414 (43.96%), Query Frame = 2
Query: 593 GIKNYSLSGNKVEYFSLKIRQFQPF----------LSVKKSFDFENPSEKQFNLSLNAIDNGGKSATLQLIVNVIDINDNPPIFQKKIVNVTIQENTTFPDAILKLNATDLDSGNNAQISYKFSSINRPIIRETFQLQSETGKIYLLKTLDYEL--YSEQNFDINVLAIDHGSPQLSDSCIIKVNV--TDINDNSPVIEI-VHSQPIPENEQITDPALKLYVSDYDSIDND-----VKCQAEKIGRRLKLEQVEKSSYFIYATEIYDYEKEKNLSLSILCQDSGKEPRYTKQLLTIFIKDVNDNRPKFLRSFYRKSINEDQEKLKPFTKVQALDKDSDDFGKVKYSIGLKDRK-YFSIDEISGEVRLANE-IDRETKDFYNVSVIA--TDGGGLKDYSYIEISILDVNDNYPKL 1762
G++ +LSG + F +I+ + L V D E + +F + ++ + + V V+D NDN P+F ++++++ I ++ A+D DSG N ++SY+ S N I L +TG I L + D +L + + I V A DHG P + ++V++ + + ++P + V+ + E+ + K+ S+ + ND +K K+G +K ++ ++ D+E E +S+ + D R L I ++ V++ P F +S Y I + ++QA+D+D G VKYSI DR+ I+E +G +RL + R ++V+A + K Y+EI DV + PKL
Sbjct: 2147 GLQIGNLSGEESREFHYRIQDPEASKIFSIDKFGRLFVAGPIDREQRATHEFQVEIDNEMMTSQKVQCKCHVIVLDENDNLPVFTSVAYYLSLKDSMAHGQKIGQIMASDQDSGENGRVSYRILSGNDLNI---VTLNPDTGSIQLNEWNDAQLDEFPNATWQILVEARDHGHPARAAVGKVQVSLKMSSWSGSAPFFVLPVYEVHVLEDTSVGTVLQKIRASNRLGMRNDGLLYSLKEHQGKLGIDVKTGELTLKTHL-------DWESEPIISMYLSVSDGNG--RSAVVPLKIVVEPVDEFAPVFTKSSYTLQIPISTPAGESVGQMQAIDEDGGVHGVVKYSI--SDRQSTVKIEEHTGIIRLQKPLVSRRNLTIEQITVVAYSSPTKQSKTTVYLEIGPFDVQPSLPKL 2546 HSP 7 Score: 70.8626 bits (172), Expect = 6.620e-12 Identity = 115/518 (22.20%), Postives = 211/518 (40.73%), Query Frame = 2
Query: 740 DNGGKSATLQLIVNVIDINDNPPIFQKKIVN-VTIQENTTFPDAILKLNATDLDSGNNAQISYKFSSINRPIIRETFQLQSETGKIYLLKTLDYELYSEQNFDINVLAIDHGSPQLSDSCIIKVNVTDINDNSPVIEIVHSQPIPENEQITDPALKLYVSDYDSIDNDV-------KCQAEKIGRRLKLEQVEKSSYFIYATEI-------YDYEKEKNLSLSILCQDSGKEPRYTKQLLTIFIKDVNDNRPKFLRSFYRKSINEDQEKLKPFTKVQALD-KDSDDFGKVKYSI----GLKDRKYFSIDEISGEVRLANEIDRETKDFYNVSVIATDGGGLKDYSYIEISILDVNDNYPKLKSG--SSMRVNENLPVGSVVGYISVIDLDLGDNSKVEWTYDFLGNSSSMLQI--ENCTVYTSTVLDRESIEHLHILITMVDMGYPRLTSSATITVSVIDENDNIPKVIYPKT----------------GSLVEEREMD-HIAVNSPKYTTVLSIKSF 2170
D G ++ + + V V D NDN P + + I E++ D + + A+D+D G N + S++ + + L ETG + L + L S Q++ I + +DHG P L ++ N +EI + P E + + + Y+S +ID + K Q E G + + S F +E D E + SL ++ SG++ + + + ++NDN P F S R+ E L+ + V + KD D+ ++Y + + +F+ID+ +G + L +D E + +++ ATD G ++ + I + D+NDN P + G I DLD ++ TY SSS+ ++ E+ ++ + + E + +T D G P ++S ++V +I E + K + K G+L E + H + P+ + + SI F
Sbjct: 1703 DGGSRNDSCTVRVTVADQNDNKPQLDASTPSELEIAESSRVGDVLHRFRASDMDIGQNGKFSFELLEDS----SGSLDLVPETGDLVLRR-----LSSLQSWKIKLRVVDHGVPGL----YVEKN----------LEISNRNPQTEAKAPLEFLKQTYLS---TIDEGLPRGQFIAKLQPELAGLTYSIVEGNIDSAFSVDSEGVIRTNLELDREILERYSLKVIGTGSGQQ---IGTRVDVRVNNLNDNVPSFPMSKPRRV----PENLRVGSYVATVGAKDVDNLAPLRYFLVSDSSGQTPTHFNIDQFTGTIHLTAPLDFEVLPEHTLTIKATD-GSFDTFTNLTIFVSDINDNAPTFSKPLYQTTVSPATFSPGQPFAKIEAHDLD----ARGALTYSLGQGSSSIFRVAPESGALFMKVL--PPAGERYLVTVTATDNGVPSFSTSVPVSV-IIGEAEPTDKPGFEKAEFRFEVMENSKIGLQIGNLSGEESREFHYRIQDPEASKIFSIDKF 2179 HSP 8 Score: 66.6254 bits (161), Expect = 1.157e-10 Identity = 138/575 (24.00%), Postives = 242/575 (42.09%), Query Frame = 2
Query: 446 VKVVIVIEDENDNAPDXXXXXXXXXXXXNDATQLDHNLPKALDKDCPIYGIKNYSLSGNKVEYFSLKIRQFQPFLSVKKSFDFENPSEKQFNLSLNAIDNG--GKSATLQLIVNVIDINDNPPIFQKKIVNVTIQENTTFPDAILKLNATDLDSGNNAQISYKFSSINRPIIRETFQLQSETGKIYLLKTLDYELYSEQNFDINVLAIDHGSPQLSDSCIIKVNVT----DINDNSPV---IEIVHSQPIPENEQITDPALKLYVSDYDSIDNDVKCQAEKIGRRLKLEQVEKSSYFIYATEIYDYEKEKNLSLSILCQDSGKEPRYTKQLLTIFIKDVNDNRPKF-LRSFYRKSINEDQEKLKP------FTKVQALDKDSDDFGKVKYSIGLKDRKYFSIDEISGEVRLANEIDRETKDFYNVSVI-----ATDGGGLKDYSYIEISILDVNDNYPKLKSGSSMRVN--ENLPVGSVVGYISVIDLDLGDNSKVEWTYDFLGNSSSMLQIENCTV--YTSTVLDRESIEHLHILIT---MVDMGYPRLTSSATITVSVIDENDNIPKVIYPKT 2086
+ + I + D NDNAP+F +S +T+ + EN + A DKD G Y ++ N EYF + + + K+S D E S ++S+ A D G +S+T ++V+D+NDNPP I + + + AI + A D D G N + Y R ++ + + G +YL + L+ E++ ++V+ D G P+ S C + V ++ DI P IEI S P C R L SS+ I ++EI ++ + L ++ + P Y+ L I + D ND + LR +E ++ TK+ L + S D G Y ++ +D+ G + LA+ + R D +N S TDG + +++ I + P+ +G +RVN E+ P GS+ I+ ++ + D+S +Y F L I+N ++ +T + +++ H H+ T +V+ ++ +TV+V D ND+ P ++ T
Sbjct: 926 MTLFIHVLDVNDNAPEFEKSWYTMEVLENSPPKTIVGKVVARDKDSLENGQIVYRIT-NGSEYFGIDEKLGNVY--TKRSIDREVIS--HVDISIVAEDKGVPPRSSTASARISVLDVNDNPPSCLS-ITPIVVPAGSPLSTAIGTIVAMDPDKGLNGSVLY------RAQLQSSLFVVKSNGDVYLRRQLNAS--DERHQRLSVIVSDQGVPRKSVVCHVPVRISKGSADIQIQEPFQKYIEIPKSCP-------------------------TGC------RLTTLNATGVSSWLIQSSEISNHFAIREGVLFMISHPIHRPP-YS---LVIVLSDKNDRQKSIQLRVLASGEAANKEETIRISDSNSIGTKIGRLGEKSAD-GSFFYRFSSEESCPLELDQTGGLLYLADGLRR--GDTHNFSCFFEKFNTTDGSA--EEMRVDLEISRTKSDKPRFDTGH-LRVNIREDTPTGSI---ITTVNATVSDDSASPISYRF------PLLIDNFSIDQFTGDITLIDTL-HWHVTPTYNLIVEAFTSGPGTTLLVTVNVDDVNDHTPFIVSQPT 1435 HSP 9 Score: 58.9214 bits (141), Expect = 2.736e-8 Identity = 140/643 (21.77%), Postives = 259/643 (40.28%), Query Frame = 2
Query: 614 SGNKVEYFSLKIRQFQPFLSVKKSFDFENPSEKQFNLSLNAIDNGGKSATLQLIVNVIDINDNPPIFQKKIVNVTIQENTTFP-DAILKLNATDLDSGNNAQISYKFSSINRPIIRETFQLQSETGKIYLLKTLDYELYSEQNFDINVLAIDHGSPQLSDSCIIKVNVTDINDNSPVIEIVHSQPIPENEQITDPALKLYVSDYDSIDNDVKCQAEKIGRRLKLEQVEKSSYFIYATEIYDYEKEKNLSLS-----ILCQDSGKEPRYTK--------QLLT---------IFIKDVNDNRPKFLRSFYRKSINEDQEKLKPFTKVQALDKDSDDFGKVKYSI-GLKDRKYFSIDEISGEVRLANEIDRETKDFYNVS----VIATDGGGLKDYSYIEISILDVNDNYPKLKSGSS---------MRVNENLPVGSVVGYISVID-LDLGDNSKVEWTYDFLGNSSSMLQIENCTVYTSTVLDRESIEHLHILITMVDMGYPRLTSSATITVSVIDENDNIPKVIYPKTGSLVEEREMDHIAVNSPKYTTVLSIKSFDPDLGINGDVLYHILPSNGSQYFIINQTSGVLKTTWIYDTISFTPLHPKED--IYKISYAAYNQVXXXXXXXXXXXXFFYVRIGPY 2422
SG +F+ I QF + + DFE E L++ A D + T L + V DINDN P F K + T+ T P K+ A DLD+ ++Y + I F++ E+G ++ +K L + + + + V A D+G P S S + V I E E P + ++ ++N KIG ++ E+S F Y I D E K S+ + +E R T +++T + + D NDN P F Y S+ + + ++ A D+DS + G+V Y I D +++ +G ++L D + +F N + V A D G + ++ + ++ SGS+ + V E+ VG+V+ I + L + ++ + + G + ++ + T LD ES + + +++ D G R SA + + ++ E + ++ K+ ++ I +++P +V +++ D D G++G V Y I S+ I + +G+++ PL + + I +I+ AY+ + Y+ IGP+
Sbjct: 1968 SGQTPTHFN--IDQFTGTIHLTAPLDFEVLPEH--TLTIKATDGSFDTFT-NLTIFVSDINDNAPTFSKPLYQTTVSPATFSPGQPFAKIEAHDLDA--RGALTYSLGQGSSSI----FRVAPESGALF-MKVLP---PAGERYLVTVTATDNGVPSFSTSVPVSVI------------------IGEAEPTDKPGFEKAEFRFEVMEN------SKIGLQIGNLSGEESREFHY--RIQDPEASKIFSIDKFGRLFVAGPIDREQRATHEFQVEIDNEMMTSQKVQCKCHVIVLDENDNLPVFTSVAYYLSLKDSMAHGQKIGQIMASDQDSGENGRVSYRILSGNDLNIVTLNPDTGSIQLNEWNDAQLDEFPNATWQILVEARDHGHPARAAVGKVQVSLKMSSW----SGSAPFFVLPVYEVHVLEDTSVGTVLQKIRASNRLGMRNDGLLYSLKEHQGKLG--IDVKTGELTLKTHLDWESEPIISMYLSVSD-GNGR---SAVVPLKIVVEPVDEFAPVFTKSSYTLQ------IPISTPAGESVGQMQAIDEDGGVHGVVKYSI--SDRQSTVKIEEHTGIIRLQ--------KPLVSRRNLTIEQITVVAYSSPTKQSKTT------VYLEIGPF 2537 HSP 10 Score: 58.151 bits (139), Expect = 3.932e-8 Identity = 124/566 (21.91%), Postives = 224/566 (39.58%), Query Frame = 2
Query: 452 VVIVIEDENDNAPDXXXXXXXXXXXXNDAT-QLDHNLPKALDKDCPIYGIKNYSLSGNKVEYFSLKIRQFQPFLSVKKSFDFENPSEKQFNLSLNAIDNGGKSATLQLIVNVIDINDNP---PIFQKKIVNVTIQENTTFPDAILKLNATDLDSGNNAQISYKFSSINRPIIRETFQLQSETGKIYLLKTLDYELYSEQNFDINVLAIDHGSPQLSDSCIIKVNVTDINDNSPVI-----------EIVHSQPIPENEQITDPALKLYVSDYDSIDNDVKCQAEKIGRRLKLEQVEKSSYFIYATEIYDYEKEK--NLSLSIL--CQDSGKEPRYT--KQLLTIFIKDVNDNRPKFLRSFYRKSINEDQEKLKPFTKVQALDKDSDDFGKVKYSIGLKDRKYFSIDEISGEVRLANEIDRETKDFYNVSVIATDGGGLKDYSYIEISILDVNDNYPKL-KSGSSMRVNENLPVGSVVGYISVIDLDLGDNSKVEWTYDFLGNSSSMLQIENCTVYTSTVLDRESIEHLHI-LITMVDMGYPRLTSSATITVSV--IDENDNIPKVI 2074
+ I + D NDNAP + S + AT K D G YSL F + F+ V P+ +++ +++ A DNG S + + V+VI P P F+K + EN+ + L +L + + Y+ I P + F + + G++++ +D E + F + + S ++ C V V D NDN PV + H Q I + + SD DS +N G L + + + I E D + ++ N + IL +D G R K +++ + + + P F+ Y + ED K++A ++ + YS+ K ID +GE+ L +D E++ ++ + +DG G ++I + V++ P KS ++++ + P G VG + ID D G + V+++ + + S ++IE T S +L I IT+V P S T+ + + D ++PK++
Sbjct: 2015 LTIFVSDINDNAP--TFSKPLYQTTVSPATFSPGQPFAKIEAHDLDARGALTYSLGQGSSSIFRVAPESGALFMKVLP------PAGERYLVTVTATDNGVPSFSTSVPVSVIIGEAEPTDKPGFEKAEFRFEVMENSK-----IGLQIGNLSGEESREFHYR---IQDPEASKIFSID-KFGRLFVAGPIDREQRATHEFQVEIDNEMMTSQKVQ--CKCHVIVLDENDNLPVFTSVAYYLSLKDSMAHGQKIGQ----------IMASDQDSGENGRVSYRILSGNDLNIVTLNPDTGSIQLNEWNDAQLDEFPNATWQILVEARDHGHPARAAVGKVQVSLKMSSWSGSAPFFVLPVYEVHVLEDTSVGTVLQKIRASNRLGMRNDGLLYSLKEHQGK-LGIDVKTGELTLKTHLDWESEPIISMYLSVSDGNGRSAVVPLKIVVEPVDEFAPVFTKSSYTLQIPISTPAGESVGQMQAIDEDGGVHGVVKYS---ISDRQSTVKIEEHTGIIRLQKPLVSRRNLTIEQITVVAYSSPTKQSKTTVYLEIGPFDVQPSLPKLL 2547 HSP 11 Score: 54.6842 bits (130), Expect = 5.462e-7 Identity = 66/292 (22.60%), Postives = 126/292 (43.15%), Query Frame = 2
Query: 1448 PKFLRSFYRKSINEDQEKLKPFTKVQALDKDSDDFGKVKYSIGLKDR---KYFSIDEISGEVRLANEIDRETKDFYNVSVIATDGGGLKDYSYIEISILDVNDNYPKLKSG-SSMRVNENLPVGSVVGYISVIDLDLGDNSKVEWTYDFLGNSSSMLQIENCTV--------YTSTVLDRESIEHLHILITMVDMGYPRLTSSATITVSVIDENDNIPKVIYPKTGSLVEEREMDHIAVNSPKYTTVLSIKSFDPDLGINGDVLYHI----LPSNGSQYFIINQTSGVLKTT 2275
P F + + ++ E + T++ + ++ KY + D K+ +DE SGE+ +D E + +++ + + G + I + + D NDN P + ++E +G+ +V D D G V GN +++ ++ + V + LDRE + +LI D G P ++ +ID NDN P ++ ++ R ++ N + ++++++ D D+G N + Y I PSN + F I+Q SGV+ TT
Sbjct: 20 PTFCQCLTKFTVPESAQI---GTRIGWISGKREESAAPKYFVVFPDEQTSKFLKVDERSGEISTIAHLDYEKRSKFDIVAVKVEESG--ETIDILVEVDDENDNAPSFADQVVKLEISEFAQLGTSFALPTVTDGD-GPKFDVHRFVILQGNVNNVFKLASRKVNEQLQADLVVNGQLDREFRDKYELLIEAQDGGKPAKIGQLRCSIEIIDANDNAP--VFSRS------RYTASVSANISIGSHLITVQATDADIGENSRISYDIKKTSAPSNSN--FAISQ-SGVITTT 294
BLAST of Protocadherin alpha-2 vs. Ensembl Celegans
Match: cdh-4 (Cadherin-4 [Source:UniProtKB/TrEMBL;Acc:A0A1C3NSI5]) HSP 1 Score: 135.576 bits (340), Expect = 1.235e-31 Identity = 166/603 (27.53%), Postives = 279/603 (46.27%), Query Frame = 2
Query: 698 NPSEKQFNLSLNAIDNG--GKSATLQLIVNVIDINDNPPIFQKKIVNVTIQENTTFPDAILKLNATDLDSGNNAQISYKFSSINRPIIRETFQLQSETGKIYLLKTLDYELYSEQN-FDINVLAIDHGSPQLSDSCIIKV----NVTDI-------------NDNSPVI----EIVHSQPIPENEQITDPALKLYVSDYDS--------IDNDVKCQAEKIGRRLKLEQVEKSSYFIYATEIYDYEKEK----NLSLSILCQDSGKEPRYTKQLLTIFIKDVNDNRPKFLRSFYRKSINEDQEKLKPFTKVQALDKDSDDFGKVKYSIGLKDRK--YFSIDEISGEVRLANEIDRETKDFYNVSVIATDGGGLKDYSY--IEISILDVNDNYPK-LKSGSSMRVNENLPVGSVVGYISVIDLDLGDNSKVEWTYDFLGNSSSM-LQIEN---CTVYTSTV--LDRESIEHLHILITMVDMGYPRLTSSATITVSVIDENDNIPKVIY---PKTGSLVEEREMDHIAVNSPKYTTVLSIKSFDPDLGINGDVL-YHILPSNGSQYFIINQTSGVLKTTWIYDT-------ISFTPLHPKEDIYK 2332
N SE+ +N + A +G K A + + ++D ND+ P+F K + T D ++K++ATD D G N +I YKF+S ++ + TG+I L+ E+ + N + V AID G P LS + + N T I N +SPV EIV + E+ I KL +D D+ + +D+ + ++ L E+S A+++ KEK ++ L + D+G + + + + + IKDVN++ P+F Y I+E+++ K KV A D D + GK+K+S+G K SID +G V+L +DRE +D + ++IA+D G S + IS+ DVNDN PK + S R+ E+LP G+ V ++ D D+G NSK++ FL NS + +I++ C + LD ++ I + D G P L++S + V ++D N + + K S+ E E+ + ++ K + + + L Y I+ +G +F I+Q G ++TT + D I+ K D+YK
Sbjct: 452 NRSERVYNFKVIASLHGINEKLAEKDVSIEILDSNDHAPVFSAKWMRQTPIVIGKPGDVLVKVDATDQDEGENGKIVYKFTS------ELPLEINANTGEITLV-----EVPKKGNSWPATVWAIDLGLP-LSRMSALNLMFYKNGTKIPAKPKPIIIQESENKHSPVFSSFPEIVE---VTEDAPIGTVVAKLQANDEDTGYNGFIRYVIHDIAGSSHEV-----LTVDEQSGEITVASDLSKLMKEKLEVLDVQLKVSAIDAGTPVKSSVKTMKLRIKDVNNHSPQFDEVSYYLRISENEKPGKDIFKVTANDFDGGNNGKIKFSLGNNQEKSSVISIDAKTGIVKLLKSLDREDQDVHTFAIIASDEGFPMRVSVTNLTISVEDVNDNPPKCVVQHSRARIPEDLPHGAFVSCMAAFDEDIGQNSKLK----FLLNSEKVPFRIDHHSGCIFIHAPEYPLDYHKTPFFNLSIEVADHGDPILSTSCHLHVELVDIAHNHLAIEFDDVAKEASVYENSEIGTEVI-------MIEAKETGDEQKVKAENLEYRIIGGDGWPHFSIDQ-KGTVRTTHLLDRETKSAYWITVEARDSKTDLYK 1022 HSP 2 Score: 131.724 bits (330), Expect = 1.990e-30 Identity = 163/564 (28.90%), Postives = 247/564 (43.79%), Query Frame = 2
Query: 722 LSLNAIDNGG--KSATLQLIVNVIDINDNPPIFQKKIVNVTIQENTTFPDAILKLNATDLDSGNNAQISYKFSSINRPIIRETFQLQSETGKIYLLKTLDYELYSEQNFDINVLAIDHGSPQLSDSCIIKVNVTDINDNSPVIEIVHSQP-IPENEQITDPALKLYVSDYDSIDNDVKCQAEKIGRRLKLEQV------EKSSYFIYATEI-YDYEKEKNLSLSILCQDSGKEPRYTKQLLTIFIKDVNDNRP--KFLRSFYRKSINEDQEKLKPFTKVQALDKDSDDFGKVKYS------IGLKDRKYFSIDEISGEVRLANEIDRETKDFYNVSVIATDGGG-------LKDYSYIEISILDVNDNYPKLKSGSSM-RVNENLPVGSVVGYISVIDLDLGDNS-------KVEWTYDFLGNSSSMLQIENCTVYTSTV----LDRESIEHLHILITMVDMGYPRLTSSATITVSVIDENDNIPKVIYPKTGSLVEEREMDHIAVNSPKYTTVLSIKSFDPDLGINGDVLYHILPSNGSQYFIINQTSGVLKTTWIYDTISFT 2302
L ++AID G KS+ + + + D+N++ P F + + I EN I K+ A D D GNN +I KFS N + ++TG + LLK+LD E F I +A D G P + ++V D+NDN P + HS+ IPE D +VS + D D+ Q K+ L E+V FI+A E DY K +LSI D G T L + + D+ N +F S+ E+ E ++A K++ D KVK IG +FSID+ G VR + +DRETK Y ++V A D +D ++ I ILD ND+ P K + V EN P V+ + D D DN K+E G+ S +I+ + Y +T LDRE + +++ D G P+L S+ + V+V+DENDN P + + H +V S + I + D D G N + Y+I + G F I+ ++ + I+ S+
Sbjct: 688 LKVSAIDAGTPVKSSVKTMKLRIKDVNNHSPQFDEVSYYLRISENEKPGKDIFKVTANDFDGGNNGKI--KFSLGNNQEKSSVISIDAKTGIVKLLKSLDREDQDVHTFAI--IASDEGFPMRVSVTNLTISVEDVNDNPPKCVVQHSRARIPE-----DLPHGAFVSCMAAFDEDIG-QNSKLKFLLNSEKVPFRIDHHSGCIFIHAPEYPLDYHKTPFFNLSIEVADHGDPILSTSCHLHVELVDIAHNHLAIEFDDVAKEASVYENSEIGTEVIMIEA--KETGDEQKVKAENLEYRIIGGDGWPHFSIDQ-KGTVRTTHLLDRETKSAYWITVEARDSKTDLYKDPRRRDVLHVFIRILDRNDHRPVAKKPMYIASVAENSPANVVIVKVEATDADDVDNDAAAPLMFKIE-----RGDPQSFFRIDLTSGYITTSGIRRLDREKQSEHELWVSICDGGEPQLCSNVIVIVNVLDENDNSPTFT----------QAIHHYSVRSKFAGKLCRIFAVDADEGENARLTYNI--TEGDARFSIDNNGNIIASEAIHGDESYA 1221 HSP 3 Score: 124.79 bits (312), Expect = 2.171e-28 Identity = 162/606 (26.73%), Postives = 270/606 (44.55%), Query Frame = 2
Query: 452 VVIVIEDENDNAPDXXXXXXXXXXXXNDATQLDHNLPKALDKDCPIYGIKNYSLSGNKVEYFSLKIRQFQPFLSVKKSFDFENPSEKQFNLSLNAIDNGGKSATLQLIVNVIDINDNPPIFQKKIVNVTIQENTTFPDAILKLNATDLD-SGNNAQISYKFSSINRPIIRETFQLQSETGKIYLLKTLDYELYSEQNFDINVLAIDHGSPQLSDSCIIKVNVTDIND--------NSPVIEIVHSQP---IPENEQITDPALKLYVSDYDSIDNDVKCQAEKIGRRLKLEQVEKSSYFIYATEIYDYEKEKNLSLSILCQDSGKEPRYTKQLLTIFIKDVNDNRPKFLRSFYRKSINED----QEKLKPFTKVQALDKDSDDFGKVKYSIGLKDRKYFSIDEISGEVRLANEIDRETKDFYNVSVIATDGGGLKDYSYIEISILDVNDNYPKL-KSGSSMRVNENLPVGSVVGYISVIDLDLGDNSKVEWTYDFLGNSSSMLQIENCT--VYTSTVLDRESIEHLHILITMVDMGYPRLTSSATITVSVIDENDNIPKVIYPKTGSLVEEREMDHIAVNSPKYTTVLSIKSFDPDLGINGDVLYHI 2212
V + I D NDNAP F +I E+ A + A+D+D G +SL + YF L + +L+V D E + L A D GG + L + V D+ND+PP F+K+ N+ + +T P IL + D D S NN S P E ++ LLK + + ++ + + V A D S +K+N+ D N VI +S+ + + P + +SD D + R + +V++S DYEK + L L E K+L+T+ I+++NDNRPK + + SI+E+ ++ + T++ A D D F ++K+ + F ID+I+G V + +D E F+N++V+A+DG +D + I ++++D NDN P KS SM+V E+ +G + + D N +E+ Y + +S + + T + + LD E++ L + + D G P L + A + +SV+DENDN PK +E+ + + NS VL++K+ D D G V Y +
Sbjct: 2698 VTVDIGDVNDNAPAFHGDYERFTISEDAAVGTSVTIFSAMDRDDSPSGRIRFSLV-EENPYFDLN--ENSGWLTVASQLDREKID--HYKLIARATDEGGFNTDLPFTIVVSDVNDSPPQFEKEEFNIDLHLPSTSP--ILHFSIKDDDLSPNNV------SQFFIPKGNEEGVFWIDSNNDLLLKRPEI-VENKMQYQLKVTAFDG---VFETSTKVKINLKSSKDSDIRCPEANKTVILAENSKKGTVVLGESSLLGPNVTFKLSDNDG-------NVFVVNFRNGIVKVKESDQI-------DYEKNQQLEFHRLTIQDNSE--VCKELITVVIENLNDNRPKIIEKLLKVSIDENLPTSEDARQYITRIVAEDAD---FDEIKFRMVDDFGGLFQIDDINGVVTVVKPLDSEILGFFNLTVVASDGE-FEDKATILVTVIDQNDNAPTFEKSTYSMKVMESESIGYELAHFRASGGD--QNETIEY-YLKPSDVTSFVNLNAQTGILTLAKPLDFETLSALKLTVVAKDSGVPPLETEAQVEISVMDENDNAPK--------FEKEKYVGKVKENSKSGEKVLTVKALDVDSEHFGAVSYEL 3255 HSP 4 Score: 109.768 bits (273), Expect = 8.204e-24 Identity = 99/386 (25.65%), Postives = 182/386 (47.15%), Query Frame = 2
Query: 707 EKQFNLSLNAIDNGGKSATLQLIVNVIDINDNPPIFQKKIVNVTIQENTTFPDAILKLNATDLDSGNNAQISYKFSSINRPIIRETFQLQSETGKIYLLKTLDYELYSEQNFDINVLAIDHGSPQLSDSCIIKVNVTDINDNSPVIEIVHSQ-PIPENEQITD--PALKLYVSDYDSIDNDVKCQAEKIGRRLKLEQVEKSSYFIYATEIYDYEKEKNLSLSILCQDSGKEPRYTKQLLTIFIKDVNDNRPKFLRSFYRKSINEDQEKLKPFTKVQALDKDSDDFGKVKYSIGLKDRKYFSIDEISGEVRLANEIDRETKDFYNVSVIATDGGGLKDYSYIEISILDVNDNYPKLKSGSSMRVNENLPVGSVVGYISVIDLDLGDN 1855
+K++ + L D G+ A L ++VIDIND PP F + +I E+ D ++ ++ATD D + + S S + + F + G I + K L+++ + + + A D +P + ++VN+ + P H + E+ + + ++ ++ D I + +E+ L VE+S+ I D E++ ++I +G T +T+ I DVNDN P F + R +I+ED T A+D+D G++++S+ +++ YF ++E SG + +A+++DRE D Y + ATD GG I + DVND+ P+ + ++ +LP S + + S+ D DL N
Sbjct: 2470 DKRYQIPLVVEDATGRRAFSTLTLSVIDINDKPPFFVLPFYSTSISESAKEGDTVMMVSATDDDENDTIEYSLLDGSES-----QFFSVHPRQGTITVAKKLEHK--AGVTLSLTIKATDSANPPHHATTTVEVNIASESVKVPRFSNSHYLFSVMEDADVGNVIGRVQQMETEIDEIRFTIVPGSEESDSFLPF-SVERSTGKIIVKSSLDRERKNQWKMTIRADAAGGVHAITT--VTVDIGDVNDNAPAFHGDYERFTISEDAAVGTSVTIFSAMDRDDSPSGRIRFSL-VEENPYFDLNENSGWLTVASQLDREKIDHYKLIARATDEGGFNTDLPFTIVVSDVNDSPPQFEK-EEFNIDLHLPSTSPILHFSIKDDDLSPN 2843 HSP 5 Score: 109.383 bits (272), Expect = 1.131e-23 Identity = 131/463 (28.29%), Postives = 207/463 (44.71%), Query Frame = 2
Query: 605 YSLSGNKVEYFSLKIRQFQPFLSVKKS--FDFENPSEKQFNLSLNAIDNGGKSATLQLIVNVID-INDNPPIFQKKIVNVTIQENT-TFPDA---ILKLNATDLDSGNNAQISYKFSSINRPIIRE---TFQLQSETGKIYLLKTLDYELYSEQNFDINVLAIDHGSPQLSDSCIIKVNVTDINDNSPVIE-IVHSQPIPENEQITDPALKLYVSDYDSIDNDVKCQAEKIGRRLKLEQV------EKSSYFIYATEIYDYEKEKNLSLSILCQDSGKEPRYTKQLLTIFIKDVNDNRPKFLRSFYRKSINEDQEKLKPFTKVQALDKDSDDFGKVKYSIGLKDRKY-------FSIDEISGEVRLANEIDRETKDFYNVSVIATDGGG--LKDYSYIEISILDVNDNYPKLKSGS-SMRVNENLPVGSVVGYISVIDLDLGDNSKVEWTYDFLGNSSSMLQI 1912
+ LS N F + R + VK+S D+E + +F+ L DN +LI VI+ +NDN P +K++ V+I EN T DA I ++ A D D F I ++ + FQ+ G + ++K LD E+ F++ V+A D + D I V V D NDN+P E +S + E+E I S D Q E I LK V + + + D+E L L+++ +DSG P T+ + I + D NDN PKF + Y + E+ + + V+ALD DS+ FG V Y + + F+I+ +G+V ++ ID E YN+ VIA DGG L+ + +EI + D ND+ P + + V E +G + SV DLD G + +T + G+ + ++
Sbjct: 2944 FKLSDNDGNVFVVNFRN--GIVKVKESDQIDYEKNQQLEFH-RLTIQDNS--EVCKELITVVIENLNDNRPKIIEKLLKVSIDENLPTSEDARQYITRIVAEDAD----------FDEIKFRMVDDFGGLFQIDDINGVVTVVKPLDSEILG--FFNLTVVASDG---EFEDKATILVTVIDQNDNAPTFEKSTYSMKVMESESIGYELAHFRASGGD--------QNETIEYYLKPSDVTSFVNLNAQTGILTLAKPLDFETLSALKLTVVAKDSGVPPLETEAQVEISVMDENDNAPKFEKEKYVGKVKENSKSGEKVLTVKALDVDSEHFGAVSYELEIVSETTTDTPVLPFAINS-NGDVLISQSIDYEKIKKYNLKVIAKDGGRPPLRSEALLEIHVEDENDHAPTFDDCNMTALVQEGEAIGHRLLKFSVSDLD-GPKNGAPFTVEIQGDGAKSFKV 3376 HSP 6 Score: 95.5153 bits (236), Expect = 2.091e-19 Identity = 125/503 (24.85%), Postives = 238/503 (47.32%), Query Frame = 2
Query: 326 VFDRDDVNNVCGPLGCCDKPSCEIVLDIIVTVIPKNERIPVKVVIVIE--DENDNAPDXXXXXXXXXXXXNDAT--QLDHNLPKALDKDCPIYGIKNYSLSGNKVEYFSLKIRQFQPFLSVKKSFDFENPSEKQFNLSLNAIDNGGK--SATLQLIVNVIDINDNPPIFQKKIVNVTIQENTTFPDAILKLNATDLDSGNNAQISYKF-----SSINRPIIRETFQLQSETGKIYLLKTLDYELYSEQNFDINVLAIDHGSPQLSDSCIIKVNVTDINDNSPVIEIVH-SQPIPENEQITDPALKLYVSDYDSIDNDVKCQAEKIGRRLKLEQVEKSSYFIYATEIYDYEKEKNLSLSILCQDSGKEPRYTKQLLTIFIKDVNDNRPKFLRSFYRKSINEDQEKLKP--FTKVQALDKDSDD------FGKVKYSIG--------LKDRKYFSIDEISGEVRLANEIDRETKDFYNVSVIATDGGGLKDYSYIEISILDVNDN 1750
+F DD+N V + D EI+ +TV+ + K I++ D+NDNAP F +S++++ + E+++ +L H D++ I Y L + V F + + L++ K DFE S L++ A D+G Q+ ++V+D NDN P F+K+ ++EN+ + +L + A D+DS + +SY+ ++ + P++ F + S G + + +++DYE + +++ V+A D G P L +++++V D ND++P + + + + E E I LK VSD D N E G K +V + + A ++ +Y K+ L+++ +D + + T LTIFI+ + + P + IN Q +L +++A D+D +D FG V+ SI + F +D +G++ + I T+ + +V TD SY+E+ + ++++
Sbjct: 3058 LFQIDDINGVVTVVKPLDS---EILGFFNLTVVASDGEFEDKATILVTVIDQNDNAPTFEKSTYSMKVMESESIGYELAHFRASGGDQNETI----EYYLKPSDVTSF-VNLNAQTGILTLAKPLDFETLS--ALKLTVVAKDSGVPPLETEAQVEISVMDENDNAPKFEKEKYVGKVKENSKSGEKVLTVKALDVDSEHFGAVSYELEIVSETTTDTPVL--PFAINS-NGDVLISQSIDYEKI--KKYNLKVIAKDGGRPPLRSEALLEIHVEDENDHAPTFDDCNMTALVQEGEAIGHRLLKFSVSDLDGPKNGAPFTVEIQGDGAKSFKVNEKLELLTAKKL-EYRKKDKYLLTVIAKDV--KGKTTDCPLTIFIRQTSRHAPTM--KPMKIQINTLQNELPEGIIGRLKASDEDEEDQNGLLRFGLVEGSIQSPRAQVQESRSTHLFRVDPNTGDIWSDHSI---TQGLHTFNVTVTD-SKFNTVSYVEVHVTSIDND 3536 HSP 7 Score: 91.6633 bits (226), Expect = 3.334e-18 Identity = 121/486 (24.90%), Postives = 204/486 (41.98%), Query Frame = 2
Query: 452 VVIVIEDENDNAPDXXXXXXXXXXXXNDATQLDHNLPKALDKDCPIYGIKNYSLSGNKVEYFSL-------KIRQFQPFLSVKKSFDFENPSEKQFNLSLNAIDNGGKSATLQLIVNVIDINDNPPIFQKKIVNVTIQENTTFPDAILKLNATDLDSGNNAQISYKFSSINRPIIRETFQLQSETGKIYLLKTLDYELYSEQNFDINVLAIDHGSPQLSDSCIIKVNVTDINDNSPVIEI-VHSQPIPENEQITDPALKLYVSDYDS-----IDNDVKCQAEKIGRRLKLEQVEKSSYFIYATEIYDYEKEKNLSLSILCQDSGKEPRYTKQLLTIFIKDVNDNRPKFLRSFYRKSINEDQEKLKPFTKVQALDKDSDDFGK-VKYSIGLKDRKYFSIDEISGEVRLANEIDRETKDFYNVSVIATDGGGLKDYSYIEISILDVNDNYPKLKSGSSMRVNEN-----LPVGSVVGYISVIDLDLGD 1852
+ +VIE+ NDN P E +D NLP + D I I +++++ + +I ++V K D E FNL++ A D G ++V VID NDN P F+K ++ + E+ + + A+ D + K S + + L ++TG + L K LD+E S + V+A D G P L ++++V D NDN+P E + + EN + + L + D DS + +++ +E L S+ + ++ DYEK K +L ++ +D G+ P ++ LL I ++D ND+ P F + E + K D D G I K F ++E E+ A +++ KD Y ++VIA D G + I I + + P +K M++ N LP G ++G + D D D
Sbjct: 2997 ITVVIENLNDNRPKIIEKLL--------KVSIDENLPTSEDARQYITRIVAEDADFDEIKFRMVDDFGGLFQIDDINGVVTVVKPLDSEILG--FFNLTVVASD-GEFEDKATILVTVIDQNDNAPTFEKSTYSMKVMESESIGYELAHFRASGGDQNETIEYYLKPSDVTSFV-----NLNAQTGILTLAKPLDFETLSA--LKLTVVAKDSGVPPLETEAQVEISVMDENDNAPKFEKEKYVGKVKENSKSGEKVLTVKALDVDSEHFGAVSYELEIVSETTTDTPVLPFAINSNGDVLISQSIDYEKIKKYNLKVIAKDGGRPPLRSEALLEIHVEDENDHAPTFDDCNMTALVQEGEAIGHRLLKFSVSDLDGPKNGAPFTVEIQGDGAKSFKVNE-KLELLTAKKLEYRKKDKYLLTVIAKDVKGKTTDCPLTIFIRQTSRHAPTMK---PMKIQINTLQNELPEG-IIGRLKASDEDEED 3459 HSP 8 Score: 78.1814 bits (191), Expect = 3.926e-14 Identity = 117/528 (22.16%), Postives = 222/528 (42.05%), Query Frame = 2
Query: 764 LQLIVNVIDINDNPPIFQKKIVNVTIQENTTFPDAILKLNATDLDSGNNAQISYKFSSINRPIIRETFQLQSETGKIYL--LKTLDYELYSEQNFDINVLAIDHGSPQLSDSCIIKVNVTDINDNSPVI-EIVHSQPIPENEQITDPALKLYVSDYDSIDN----------DVKCQAEKIGRRLKLEQVEKSSYFIYATEIYDY----EKEKNLSLSILCQDSGKEPRYTKQLLTIFIKDVNDNRPKFL---RSFYRKSINEDQEKLKPFTKVQALDKDSDDFGKVKYSIGLKD-RKYFSIDEISGEVRLANEIDRETKDFYNVSVIATDGGGLKDYSYIEISILDVNDNYPKLKSGS-SMRVNENLPVGSVVGYISVIDLDLGDNSKVEWTY---DFLGNSSSMLQIENCTVYTSTVLDRESIEHLHILITMVDMGYPRLTSSATITVSVIDENDNIPKVIYPKTGSLVEERE-MDHIAVNSPKYTTVLSIKSFDPDLGINGDVLYHILPSNGSQYFIINQTSGVLK 2269
L + + ++D ND+ P+ +K + ++ EN+ I+K+ ATD D +N + I R + F++ +G I ++ LD E SE +++ D G PQL + I+ VNV D NDNSP + +H + + +++ D D +N D + + G + E + + + D+ ++ + + +G++PR +K N P + +S Y I++ + K++A D D D+ +SI D F + + +G++ LA +++ + +++ TDG D+S + I + PK + V+E + VG+ + + LG V + D ++ + V LD E+ + +V + + S AT +V++ DENDN P + + V+E + +D + + ++ +FD D G NG V Y I+ N F I+ SG ++
Sbjct: 1030 LHVFIRILDRNDHRPVAKKPMYIASVAENSPANVVIVKVEATDADDVDNDAAAPLMFKIERGDPQSFFRIDLTSGYITTSGIRRLDREKQSEHELWVSIC--DGGEPQLCSNVIVIVNVLDENDNSPTFTQAIHHYSV--RSKFAGKLCRIFAVDADEGENARLTYNITEGDARFSIDNNGNIIASEAIHGDESYALTVQATDHGTPGQQFAATRVVLTANSAGQKPRKSK------------NSPPEISGKKSDYVIPISDADQVGLTVGKLEASDADGDELW---WSISSGDPDSVFDVRQDTGQLLLAKKVELLKRGELRLNISVTDGQAW-DHSTVIIQVSRQISQRPKFSASHYQTDVSERVAVGTQIYTLKASGESLGTKPLVFNLFSVDDVAMEDKIRVEPSSGNVIVMEPLDYEAARRIR---AVVQVQQANMKSFATFSVNINDENDNSPYFVGHTAFAFVDESDTVDDV---------LATVTAFDKDRGENGIVTYSIVSGNEESLFKIDAKSGEVR 1525 HSP 9 Score: 75.485 bits (184), Expect = 2.287e-13 Identity = 117/580 (20.17%), Postives = 253/580 (43.62%), Query Frame = 2
Query: 605 YSLSGNKVEYFSLKIRQFQPFLSVKKSFDFENPSEKQFNLSLNAIDNGGK-SATLQLIVNVIDINDNPPIFQKKIVNVTIQENTTFPDAILKLNATDLDSGN-----NAQISYKFSSINRPIIRETFQLQSETGKIYLLKTLDY-ELYSEQNFDINVLAIDHGSPQLSDSCIIKVNVTDINDNSPVIEIVHSQPIPENEQITD-------------PALKLYVSDYDSIDNDVKCQAEKIGRRLKLEQVEKSSYFIYATEIYDYEKEKNLSLSILCQDSGKEPRYTKQLLTIFIKDVNDNRPKFLRSFYRKSINEDQEKLKPFTKVQALDKDSDDFGKVKYS-IGLKDRKYFSIDEISGEVRLANEIDRETKDFYNVSVIATDGGGLKDYS--YIEISILDVNDNYPKLKSGSSM-RVNENLPVGSVVGYISVIDLDLGDNSKVEWTYDFLGNSSSMLQIENCT--VYTSTVLDRESIEHLHILITMVDMGYPRLTSSATITVSVIDENDNIPKVIYPKTGSLVEEREMDHIAVNSPKYTTVLSIKSFDPDLGINGDVLYHILPSNGSQYFIINQTSGVL 2266
YSLSG+K ++I +++ D+E ++++L L A +G + S+ + IV + D+ND P F + V+ I ++ I ++ATD+D+ N + ++ YK + + F + TG++ L + ++ +L +E + +++ G ++++ + P E H I + P L+ ++ S ++ +A + +++ + I+ + + +Y ++K + ++ +D+ R LT+ + D+ND P F+ FY SI+E ++ V A D D +D ++YS + + ++FS+ G + +A +++ + ++++ ATD ++ +E++I + P+ + + V E+ VG+V+G + ++ ++ + +S +E T + + LDRE + I G + + T+TV + D NDN P + + E I+ ++ T+V + D D +G + + ++ N YF +N+ SG L
Sbjct: 2221 YSLSGSK----DIEIHPETGDVTITGQLDYEK--TQKYDLKLVATSSGKQVSSEAEFIVLIEDVNDEMPEFIRSDVSAKISDSAITGQFITIMSATDMDTTNSLDEESQKLLYKIVDGDETL----FNISPATGELSLARPVEQDDLVNEDTKKVLNVSVTDGMFTAYAKLVVEILRSGSMQPPPRFEQSHYVANALENTIVNKSALLTVAVKGGVPPLQFSLAPTTSSNSSTSKEAWPVA-------IDRKTGRIHVSRVLNYHRDKRYQIPLVVEDATG--RRAFSTLTLSVIDINDKPPFFVLPFYSTSISESAKEGDTVMMVSATDDDEND--TIEYSLLDGSESQFFSVHPRQGTITVAKKLEHKAGVTLSLTIKATDSANPPHHATTTVEVNIASESVKVPRFSNSHYLFSVMEDADVGNVIGRVQQMETEIDEIRFTIVPGSEESDSFLPFSVERSTGKIIVKSSLDRERKNQWKMTIRADAAG--GVHAITTVTVDIGDVNDNAP--------AFHGDYERFTISEDAAVGTSVTIFSAMDRDDSPSGRIRFSLVEEN--PYFDLNENSGWL 2767 HSP 10 Score: 67.3958 bits (163), Expect = 7.950e-11 Identity = 87/350 (24.86%), Postives = 137/350 (39.14%), Query Frame = 2
Query: 1286 QVEKSSYFIYATEIYDYEKEKNLSLSILCQDSGKEPRYTKQLLTIFIKDVNDNRPKFLRSFYRKSINEDQEKLKPFTKVQALDKDSDDFGKVKYSI-GLKDRKYFSIDEISGEVRLANEIDRE---TKDFYNVSVIATDGGGLKDYSYIEISILDVNDNYPKLKSGSSMRVNENLPVGSVVGYISVIDLDLGDNSKVEWTYDFLGNSSSMLQIENCTVYTSTVLDRESIEHLHILITMVDMGYPRLTSSATITVSVIDEND---NIPKVIYPKTGSLVEEREM--DHIAVNSPKYTTVLS-------IKSFDPDLGINGDVLYHILPSNGSQYFIINQTSGVLKTTWIYD 2287
+VE SS + E DYE + + + Q + + T ++ I D NDN P F+ ++E V A DKD + G V YSI + F ID SGEVRLA +D E + + I + LKD E+S+ N N + +V + S V+ L+ + V + + NCT + L +H+ + + + + I S + D I K+I S + R++ I N P ++VLS + + D D G NG V Y +L Q F ++Q SG ++T +D
Sbjct: 1414 RVEPSSGNVIVMEPLDYEAARRIRAVVQVQQANMKSFAT---FSVNINDENDNSPYFVGHTAFAFVDESDTVDDVLATVTAFDKDRGENGIVTYSIVSGNEESLFKIDAKSGEVRLAKPLDPELQHVESILRIRAIDSAANSLKD----EMSLHIRNSNEAPETAKFDRKVYQTTLYDSTRPGTPVLVLNALHHGTVSYKLE-----------PNCTFFEVHTLSGA----VHLATWLTKLKHRKSVECTAIVESTEGQQDIAKVIAKIIRTNQHSPIFRRQVYRGTIRENMPTGSSVLSKSLLPLVVSAIDEDPGSNGLVGYRMLSPKDEQMFSVDQYSGAIRTQMSFD 1741 HSP 11 Score: 63.1586 bits (152), Expect = 1.571e-9 Identity = 122/484 (25.21%), Postives = 209/484 (43.18%), Query Frame = 2
Query: 464 IEDENDNAPDXXXXXXXXXXXXNDATQLDHNLPKALDKDCPIYGIKNYSL-SGNKVEYFSLKIRQFQPFLSVKKSFDFENPSEKQFNLSLNAIDNGGKSATLQLIVNVIDINDNPPI--FQKKIVNVTIQENTTFPDAILKLNATDLDSGNNAQISYKFSSINRPIIRETFQLQSETGKIYLLKTLDYELYSEQNFDINVLAIDHGSPQLSDSCIIKVNVTDINDNSPVI-EIVHSQPIPEN-----EQITDPALKLYVSDYDSIDNDVKCQAEKIGRRL---KLEQ---VEKSSYFIYATEIYDYEKEKNLSLSILCQDSGKEPRYT--KQLLTIFIKDVNDNRPKFLRSFYRKSINEDQEKLKPFTKVQALD----KDSDDFGKVKYSIGLKDRKY-FSIDEISGEVRL--ANEIDRETKDFYNVSVIATDGGGLKDYSYIEISILDVNDNYPKLKSG---SSMRVNENLPVGSVVGYISVI 1834
I DENDN+P F + + E+D A DKD GI YS+ SGN+ F + + + L+ K D E + L + AID+ S ++ +++ + N+ P F +K+ T+ ++T +L LNA ++ +SYK F++ + +G ++L L + + + AI + D + + N +SP+ V+ I EN ++ L L VS +ID D +G R+ K EQ V++ S I +D+EK K S + D G+ PR + L+ + + D ND P+F S + D + P ++ +D D G ++Y I KD+ FS+D +G+V + +N I TK +++ V TDG Y ++IS + ++ K +S+ N LP GS++ ++ I
Sbjct: 1457 INDENDNSPYFVGHTAFAFVDESDTVDDVLATVTAFDKDRGENGIVTYSIVSGNEESLFKIDAKSGEVRLA--KPLDPELQHVESI-LRIRAIDSAANSLKDEMSLHIRNSNEAPETAKFDRKVYQTTLYDSTRPGTPVLVLNAL-----HHGTVSYKLEPNC-----TFFEVHTLSGAVHLATWLTKLKHRKS---VECTAIVESTEGQQDIAKVIAKIIRTNQHSPIFRRQVYRGTIRENMPTGSSVLSKSLLPLVVS---AIDEDPGSNG-LVGYRMLSPKDEQMFSVDQYSGAIRTQMSFDFEKMKEYSFYVQAFDMGQPPRRSLMPSLIVVTVIDENDEPPRF------PSNSLDISMILPTANGVSVGGQTAQDMDSVGSLRYFI--KDQSVPFSVDSKTGDVLVKDSNGISDMTK-LFDLEVFVTDGKQSASY-VMKISTISTENSKFKFTRNEYHTSLIENTTLPPGSIILSVATI 1910
BLAST of Protocadherin alpha-2 vs. Ensembl Celegans
Match: hmr-1 (Cadherin-related hmr-1 [Source:UniProtKB/Swiss-Prot;Acc:Q967F4]) HSP 1 Score: 129.798 bits (325), Expect = 6.306e-30 Identity = 162/632 (25.63%), Postives = 281/632 (44.46%), Query Frame = 2
Query: 281 QYFRISD-SGEIRITKVFDRDDVNNVCGPLGCCDKPSCEIVLDIIVTVIPKNE---RIPVKVVIVIEDENDNAPDXXXXXXXXXXXXNDATQLDHNLPKALDKDCPIYGIKNYSLSGNKVEYFSLKIRQFQPFLSVKKSFDFENPSEKQFNLSLNAIDNGGKSATLQLIVNVIDINDNPPIF-QKKIVNVTIQENTTFPDAILKLNATDLDSGN-NAQISYKFSSINRPIIRETFQLQSETGKIYLLKTLDYELYSE-QNFDINVLAIDHGSPQLSDSCIIKVNVTDINDNSPVI------------EIVHSQPI----PENEQITDPALKLYVSDYDSIDNDVKCQAEKIGRRLKLEQVEKSSYFIYATEIYDYE--KEKNLSLSILCQDSGKEPRYTKQLLTIFIKDVNDNRPKFLRSFYRKSINEDQEKLKPFTKVQALDKDSDDFGKV-KYSIGLK-DRKYFSIDEIS-----GEVRLANEIDRE---TKDFYNVSVIATDGGGLKDYSYIEISILDVNDNYPKLKSGSSMRVNENLPVGSVVGYISVIDLDLGDNSKVEWTYDFLGNSSSMLQI-ENCTVYTSTVLDRESIEHLHILITMVDMGYPRLTSSATITVSVIDENDNIPK 2068
++FRI + +GEI + FDR+ ++ + D+ V+ +P + VKV IVI D NDNAP F E + + E++ D KA D D + Y L G +R + VK+ DFE + Q++L L A D G +AT + +++ D+NDN P F Q+K I+E+ P + ++ATD D +++I Y+ E F++ +G I L+K LD + + +++ V AID L ++VNV DINDNSP+ E +HS + + DP + +Y + N + E + R +++++ I+A D E E+ + + D G R +TI + D+NDN P F ++ Y S+ E A D D + V Y + + D Y + D+ S G +R+ +D E +D +++ + +DG + + + ++++D ND+ P + + RV E++P G+ +G + D D GD ++ + + + I ++ T+ + LDRE I +++I D + V + D NDN P+
Sbjct: 1269 KHFRIDELTGEIFPNEKFDREKIDMYILTVEASDRS---------VSALPGANGPNKDNVKVQIVINDVNDNAPSFEEQKYIGRVKESEGEGHDVITIKAHDLD--KHSNLRYHLIGAGGGRIPFGVRTDSGTIFVKEPLDFE--ASDQYHLVLIASD-GRHNATTNVYIHIEDVNDNAPQFEQQKYATTVIEEDVDIPKVLFNVHATDADQDEKSSRIVYRLEGQG---ADEVFRIGKYSGTIELVKALDRDPPAGVPSWNFVVQAIDDDGNGLVGYADVQVNVRDINDNSPIFPERLFGYIEENREPIHSDGVYFMDVQARDFDDPTTENANIEYGIVRNKL-INGESVFR------IDQNTGKIFAMRSLDREISSEREFIIEVRANDRGVPSREGFANVTIKVTDMNDNAPFFEKTRYEGSVEETAPIGAAVMSFSAFDADEEAKDNVFTYQLSEESDYFYVTTDKDSKQSSVGVLRVKQPLDYEDVTQRDGFHLGIRVSDGRHDAEAA-VHVALVDRNDHAPHIHGATEHRVREDVPRGTSIGRYTATDRDAGDTAR--FRINRQSDPKRQFTIDQDGTLRVAHTLDREDIAVYNLIIEAYDNS--NNIGRQMVAVYLQDVNDNGPE 1871 HSP 2 Score: 124.02 bits (310), Expect = 3.782e-28 Identity = 158/594 (26.60%), Postives = 269/594 (45.29%), Query Frame = 2
Query: 593 GIKNYSLSGNKVEYFS--LKIRQFQPFLSVKKSFDFENPS-EKQFNLSLNAIDNGGKSATLQLIVNVIDINDNPPIFQKKIVNVTIQENTTFPDAILKLNATDLDSGNNAQISYKFSSINRPIIRETFQLQSETGKIYLLKTLDYELYSEQNF--DINVLAIDHGSP-QLSDSCIIKVNVTDINDNSPVI--EIVHSQPIPENEQITDPALKLYVSDYDSIDNDVKCQAEKIGR---RLKLEQVEKSSYFI---YATEIYDY-EKEKNLSLSILCQDSGKEPRYTKQ------LLTIFIKDVNDNRPKFLRSFYRKSINEDQE---KLKPFT--KVQALDKDSDDFGKVKYSI---GLKDRKYFSIDEISGEVRLANEI--DRETKDFYNVSVIATDGGG--LKDYSYIEISILDVNDNYPKLKSGS-SMRVNENLPVGSVVGYISVIDLDLGDNSKVEWTYDFLGNSSSMLQIENCTVYTSTVLDRESIEHLHILITMV-----------DMGYPR-LTSSATITVSVIDENDNIPKVIYP---KTGSLVEEREMDHIAVNSPKYTTVLSIKSFDPDLGINGDVLYHILPSNG 2227
G YSL G+ E + +I + + + DF++P+ K L + A ++ + + + L + + D+NDN P F + + ++E+ ILK+ A D D+G+N++I+Y + N F + S G+I LD + +E++F NV A DHG P LS S +I + + ND S V ++ + E+ Q P +++ D D D +K GR ++ L +++ + + + D E E ++L+++ QD G Y + L I I+DVN+N+P+F I + E K P T KV+A D DS G + YS+ + RK F ID +G + + + DRET+ +V+V ATD G L + + ++D+NDN P+ + S V+ VG+ V + D D N+++ TY ++++ + +N + V R L I M D G P L SSA +T++V+D+ PK K G V+E ++ +N +L ++ N DV+Y + S G
Sbjct: 567 GPITYSLEGDTPEDETKWFRIDPSTGIIHLTRLLDFDDPALPKLHKLKVTAREDN-RESHVDLTIRIDDVNDNVPTFTRPLYTAQVREDIPLNQTILKVTAVDKDTGDNSRITYSVDNHN-------FSINS-NGEISAKVRLDADQLNERHFVYRFNVTARDHGEPVSLSSSAMIHIRTENTNDESAVFLPTSQYTAFVAEDAQGGTPVIQIQARDADR-DEVTYSFMDKNGRSTQKMNLFSIDEHTGLVKLRHGVSAADLAEAENPINLTVIVQDDGSCCVYPSKTHTSYATLLIGIEDVNNNKPEFPDCAKYSDIAKIMEGTYKTDPPTIVKVEATDDDSSANGDIVYSLYYTQSESRKAFVIDRQTGVLTPSPHVVFDRETRPREDVTVKATDRGDRPLIGFCQFSVEVVDINDNSPQFERPSYETSVSRFEAVGTSVITVFAFDNDAAHNAEI--TYSLEIDTTAGEEHQNDLDFFELVNRRSGEITLIKPIPMKTQKFIFNVIADDNGIPEALQSSAQVTLNVLDKQQKAPKWQTSPDCKPGITVDE----NVELNK----VILRCRAVSSGDSRNSDVIYKLTASGG 1140 HSP 3 Score: 122.094 bits (305), Expect = 1.624e-27 Identity = 149/575 (25.91%), Postives = 258/575 (44.87%), Query Frame = 2
Query: 692 FENPSEKQFNLSLNAIDNGGKS--ATLQLIVNVIDINDNPPIFQKKIVNVTIQENTTFPDAILKLNATDLDSGNNAQISYKFSSINRPIIRET------FQL-QSETGKIYLLKTLDYELYSEQNFDINVLAIDHGSPQ-LSDSCIIKVNVTDINDNSPVIEIV-HSQP---IPENEQITDPALKL-YVSDYDSIDNDV----------KCQAEKIGRRLKLEQVEKSSYFIYATEIYDYEKEKNLSLSILCQDSGKEPRYTKQLLTIFIKDVNDNRPKFLRSFYRKSINEDQ---EKL-----KPFTKVQALDKDSDD-FGKVKYSI----GLKDRKYFSIDEISGEVRLANEIDRETKDFYNVSVIATD---------GGGLKDYSYIEISILDVNDNYPKLKSGSSM-RVNENLPVGSVVGYISVIDLDLGDNSKVEWTYDFLGNSSSMLQIENCTVYTSTVLDRESIEHLHILITMVDMGYPRLTSSATITVSVIDENDNIPKVIYPKTGSLVEEREMDHIAVNSPKYTTVLSIKSFDPDLGINGDVLYHILPSNGS-QYFIINQTSGVLK 2269
F+ + + ++++ A D G + Q V V+DINDN P F++ ++ +++ + A D D+ +NA+I+Y I+ E F+L +G+I L+K + + Q F NV+A D+G P+ L S + +NV D +P + +P + EN ++ L+ VS DS ++DV +AE R+ + + E DYE+ N +L++ D TK + + ++DVND P+F + +I+E+ E L KP V+A+D DSD +V Y I ++ K+F IDE++GE+ + DRE D Y ++V A+D G KD ++I I DVNDN P + + RV E+ G V I DLD N + G ++ ++ T++ LD E+ + H+++ D R ++ + + + D NDN P+ K + V E ++D PK + ++ + D D + + L G+ + F I + SG ++
Sbjct: 937 FDRETRPREDVTVKATDRGDRPLIGFCQFSVEVVDINDNSPQFERPSYETSVSRFEAVGTSVITVFAFDNDAAHNAEITYSLE-IDTTAGEEHQNDLDFFELVNRRSGEITLIKPIPMKT---QKFIFNVIADDNGIPEALQSSAQVTLNVLDKQQKAPKWQTSPDCKPGITVDENVELNKVILRCRAVSSGDSRNSDVIYKLTASGGPGNKAESKFRQFNKFENGNEWVEVVIMEGLDYEQVNNYTLTLTATDMTSRVASTKTFV-VEVRDVNDVVPQFTVDLFTGTIDEEMTPNEHLEKTNGKPIVTVKAIDTDSDGPQNEVHYRIVGEANGEETKHFRIDELTGEIFPNEKFDREKIDMYILTVEASDRSVSALPGANGPNKDNVKVQIVINDVNDNAPSFEEQKYIGRVKESEGEGHDVITIKAHDLDKHSNLRYHLIGAGGGRIPFGVRTDSGTIFVKEPLDFEASDQYHLVLIASDG---RHNATTNVYIHIEDVNDNAPQFEQQKYATTVIEEDVD-----IPK--VLFNVHATDADQDEKSSRIVYRLEGQGADEVFRIGKYSGTIE 1496 HSP 4 Score: 87.0409 bits (214), Expect = 7.353e-17 Identity = 166/735 (22.59%), Postives = 298/735 (40.54%), Query Frame = 2
Query: 281 QYFRISDS-GEIRITKVFDRDDVNNVCGPLGCCDKPSCEIVLDIIVTVIPKNERIPVKVVIVIEDENDNAPDXXXXXXXXXXXXNDATQLDHNLPK--ALDKDCP-----IYGIKNYSLSGNKVEYFSLKIRQFQPFLSVKKSFDFENPSEKQF--NLSLNAIDNG---GKSATLQLIVNVIDINDNPPIF-QKKIVNVTIQENTTFPDAILKLNATDLDSGNNAQISYKFSSINRPIIRET--FQLQSETGKIYLLKTLDYELYSEQNFDINVLAI--DHGSPQLSDS------CIIKVNVTDINDNSP----VIEIVHSQPIPENEQITDPA--LKLYVSDYDSIDNDVKCQAEKIGRRLKLEQVEKSSYFIYATE----------IYDYEKEKNLSLSILCQDSGKEPRYTKQLLTIFIKDVNDNRPKFLRSFYRKSINEDQEKLKPFTKVQALDKDSDDFGKVKYSIGL---------KDRKYFS-IDEISGEVRLANEIDRETKDFYNVSVIATDGG---GLKDYSYIEISILDVNDNYPKLKSGSSMR----VNENLPVGSVVGYISVIDLDLGDNSKVEWTYDFLGNSSSMLQ--------IENCTVYTSTV----LDRESIEHLHILITMVDMGYPRLTSSATITVSVIDENDNIPK-VIYPKTGSLVEEREM-DHIAVNSPKYTTVLSIKSFDPDL-GINGDVLYHIL-PSNG--SQYFIINQTSG 2260
++FRI S G I +T++ D DD P+ + + VT N V + I I+D NDN P + + + + L+ + K A+DKD Y + N++ S N S K+R D + +E+ F ++ A D+G S++ + + + ND +F + E+ ++++ A D D +++Y F N ++ F + TG + L + +E IN+ I D GS + S + + + D+N+N P + I E TDP +K+ +D DS N I L Q E F+ + ++D E +++ D G P ++ + D+NDN P+F R Y S++ + V A D D+ ++ YS+ + D +F ++ SGE+ L I +T+ F +VIA D G L+ + + +++LD PK ++ + V+EN+ + V+ + NS V + G + + EN + V LD E + + + +T DM R+ S+ T V V D ND +P+ + TG++ EE +H+ + K ++++K+ D D G +V Y I+ +NG +++F I++ +G
Sbjct: 583 KWFRIDPSTGIIHLTRLLDFDD-------------PALPKLHKLKVTAREDNRESHVDLTIRIDDVNDNVP--TFTRPLYTAQVREDIPLNQTILKVTAVDKDTGDNSRITYSVDNHNFSINSNGEISAKVR-----------LDADQLNERHFVYRFNVTARDHGEPVSLSSSAMIHIRTENTNDESAVFLPTSQYTAFVAEDAQGGTPVIQIQARDAD---RDEVTYSFMDKNGRSTQKMNLFSIDEHTGLVKLRHGVSAADLAEAENPINLTVIVQDDGSCCVYPSKTHTSYATLLIGIEDVNNNKPEFPDCAKYSDIAKIMEGTYKTDPPTIVKVEATDDDSSANG------DIVYSLYYTQSESRKAFVIDRQTGVLTPSPHVVFDRETRPREDVTVKATDRGDRPLIGFCQFSVEVVDINDNSPQFERPSYETSVSRFEAVGTSVITVFAFDNDAAHNAEITYSLEIDTTAGEEHQNDLDFFELVNRRSGEITLIKPIPMKTQKFI-FNVIADDNGIPEALQSSAQVTLNVLDKQQKAPKWQTSPDCKPGITVDENVELNKVILRCRAVSSGDSRNSDVIYKLTASGGPGNKAESKFRQFNKFENGNEWVEVVIMEGLDYEQVNNYTLTLTATDM-TSRVASTKTFVVEVRDVNDVVPQFTVDLFTGTIDEEMTPNEHLEKTNGK--PIVTVKAIDTDSDGPQNEVHYRIVGEANGEETKHFRIDELTG 1278 HSP 5 Score: 83.1889 bits (204), Expect = 9.995e-16 Identity = 102/381 (26.77%), Postives = 171/381 (44.88%), Query Frame = 2
Query: 1277 KLEQVEKSSYFIYATEIYDYEKEKNLSLSILCQDSGKEPRYTKQLLTIFIKDVNDNRPKFLRSFYRKSINEDQEKLKPFTKVQALDKDSDDFGKVKYSIGLKDRKYFSID---EISGEVRLANEIDRETKDFYNVSVIATDGG---GLKDYSYIEISILDVNDNYPKL--KSGSSMRVNENLPVGSVVGYISVIDLDLGDNSKVEWTYDFL---GNSSSMLQIENCTVYTSTVLDRESIEH---------LHILITMVDMG----YPRL--TSSATITVSVIDENDNIPKVIYPKTGSLVE-EREMDHIAVNSPKYTTVLSIKSFDPDLGINGDVLYHI--LPSNGSQYFIINQTSGVLKTT--WIYDTISFTPLHPKEDI 2326
K +++ S+ I+ T + D++ L L + ++ R + LTI I DVNDN P F R Y + ED + KV A+DKD+ D ++ YS+ D FSI+ EIS +VRL + E Y +V A D G L + I I + ND S + V E+ G+ V I D D + E TY F+ G S+ + + + +T V R + +++ + + D G YP TS AT+ + + D N+N P+ +P + + M+ P T++ +++ D D NGD++Y + S + F+I++ +GVL + ++D + P+ED+
Sbjct: 583 KWFRIDPSTGIIHLTRLLDFDDPALPKLHKLKVTAREDNRESHVDLTIRIDDVNDNVPTFTRPLYTAQVREDIPLNQTILKVTAVDKDTGDNSRITYSV---DNHNFSINSNGEISAKVRLDADQLNERHFVYRFNVTARDHGEPVSLSSSAMIHIRTENTNDESAVFLPTSQYTAFVAEDAQGGTPVIQIQARDAD-----RDEVTYSFMDKNGRSTQKMNLFSIDEHTGLVKLRHGVSAADLAEAENPINLTVIVQDDGSCCVYPSKTHTSYATLLIGIEDVNNNKPE--FPDCAKYSDIAKIMEGTYKTDPP--TIVKVEATDDDSSANGDIVYSLYYTQSESRKAFVIDRQTGVLTPSPHVVFDRET----RPREDV 947 HSP 6 Score: 74.7146 bits (182), Expect = 4.587e-13 Identity = 114/521 (21.88%), Postives = 208/521 (39.92%), Query Frame = 2
Query: 794 NDNPPIFQKKIVNVTIQENTTFPDAILKLNATDL----DSGNNAQISYKFSSINRPIIRETFQLQSETGKIYLLKTLDYELYSEQNFDINVLAIDHGSPQLSDSCIIKVNVTDINDNSPVI-EIVHSQPIPENEQITDPALKLYVSDYDSIDN------------DVKCQAEKIGR-RLKLEQVEKSSYFIYATEIYDYEKEKNLSLSILCQDSGKEPRYTKQLLTIFIKDVNDNRPKFL-RSFYRKSINEDQEKLKPFTKVQALDKDSDDFGKVKYSIGLKDRK------YFSIDEISGEVRLANEID----RETKDFYNVSVIATDGGGL--------KDYSYIEISILDVNDNYPKLKSGSSMRVNENLPVGS------VVGYISVIDLDLGDNSKVEWTYDFLGNSSSML-----QIENCTVYTSTVLDRESIEHLHILITMVDMGYPRLTSSATITVSVIDENDNIPKVIYPKTGSLVEEREMDHIAVNSPKYTTVLSIKSFDPDLGINGDVLYHI 2212
++ PP F K+ VT+ E+ +++ + A D + I+Y + F++ TG I+L + LD++ + ++ L + + + + D+NDN P +++ + E+ + LK+ D D+ DN + E + RL +Q+ + +F+Y + + + +SLS + ++ I ++ ND FL S Y + ED + P ++QA D D D+ V YS K+ + FSIDE +G V+L + + E ++ N++VI D G Y+ + I I DVN+N P+ + + G+ + + D D N + ++ + + S Q T V DRE+ + + D G L +V V+D NDN P+ P + V E AV T+V+++ +FD D N ++ Y +
Sbjct: 524 DERPPQFAKQEYEVTVSEDNLVDYSVVDVKAQSFRSFEDGRSKGPITYSLEGDTPEDETKWFRIDPSTGIIHLTRLLDFDDPALPK--LHKLKVTAREDNRESHVDLTIRIDDVNDNVPTFTRPLYTAQVREDIPLNQTILKVTAVDKDTGDNSRITYSVDNHNFSINSNGEISAKVRLDADQLNE-RHFVYRFNVTARDHGEPVSLS------------SSAMIHIRTENTNDESAVFLPTSQYTAFVAEDAQGGTPVIQIQARDADRDE---VTYSFMDKNGRSTQKMNLFSIDEHTGLVKLRHGVSAADLAEAENPINLTVIVQDDGSCCVYPSKTHTSYATLLIGIEDVNNNKPEFPDCAKYSDIAKIMEGTYKTDPPTIVKVEATDDDSSANGDIVYSLYYTQSESRKAFVIDRQTGVLTPSPHVVFDRETRPREDVTVKATDRGDRPLIGFCQFSVEVVDINDNSPQFERPSYETSVSRFE----AVG----TSVITVFAFDNDAAHNAEITYSL 1018 HSP 7 Score: 72.0182 bits (175), Expect = 2.722e-12 Identity = 157/703 (22.33%), Postives = 283/703 (40.26%), Query Frame = 2
Query: 260 SSFTKFNQYFRISDSGEIRITKVFDRDDVNNVCGPLGCCDKPSCEIVLDIIVTVIPKNERIPVKVVIVIE--DENDNAP----DXXXXXXXXXXXXNDATQLDHNLP----KALDKDCPIYGIKN---YSLSG--NKVEYFSLKIRQFQPFLSVKKSFDFENPSEKQFNLSLNAID---------NGGKSATLQLIVNVIDINDNPPIFQKKIVNVTIQENTTFPDAILKLNATDLDSGNNAQISYKFSSINRPIIRETFQLQSETGKIYLLKTLDYELYSEQNFDINVLAIDHGSPQLSDSCIIKVNVTDINDNSPVIEIVHSQPIPENEQITDPALKLYVSDYDSIDNDVKCQAEKIGRRLKLE------QVEKSSYFIYATEIYDYEKEK-----NLSLSILCQDSGKEPRYTKQLLTIFIKDVNDNRPKFLRSFYRKSINEDQEKLKP----FTKVQALDKDSD-------DFGKVKYSIGLKDRKYFSIDEISGEVRLANEIDRE--TKDFYNVSVIATDGG--GLKDYSYIEISILDVNDNYPKL-KSGSSMRVNENLPVGSVVGYISVIDLDLGDNSKV-------EWTYDFLGNSSSMLQIENCTVYTSTVLDRESI---EHLHILITMVDMGYPRLTSSATITVSVIDENDNIPKVIYPKTGSLVEEREMDHIAVNSPKYTTVLSIKSFDPDLG 2185
S F +FN++ ++ E+ I + D + VNN L D S R+ V+E D ND P D + + N+ + + P KA+D D G +N Y + G N E +I + + + FD E + L++ A D NG +++ + + D+NDN P F+++ ++E+ ++ + A DLD +N ++ I R F +++++G I++ + LD+E + + VL G + + + +++ D+NDN+P E E + P + V D+ D D K + +I RL+ + ++ K S I + D + N + + D Y + + ++D+NDN P F + I E++E + F VQA D D ++G V+ + + F ID+ +G++ +DRE ++ + + V A D G + ++ + I + D+NDN P K+ V E P+G+ V S D D V E Y ++ Q + LD E + + H+ I + D R + A + V+++D ND+ P I+ T V E + P+ T++ + D D G
Sbjct: 1147 SKFRQFNKFENGNEWVEVVIMEGLDYEQVNNYTLTLTATDMTS----------------RVASTKTFVVEVRDVNDVVPQFTVDLFTGTIDEEMTPNEHLEKTNGKPIVTVKAIDTDSD--GPQNEVHYRIVGEANGEETKHFRIDELTGEIFPNEKFDREKID--MYILTVEASDRSVSALPGANGPNKDNVKVQIVINDVNDNAPSFEEQKYIGRVKESEGEGHDVITIKAHDLDKHSN----LRYHLIGAGGGRIPFGVRTDSGTIFVKEPLDFEASDQYHL---VLIASDGRHNATTN--VYIHIEDVNDNAPQFEQQKYATTVIEEDVDIPKVLFNVHATDA-DQDEK--SSRIVYRLEGQGADEVFRIGKYSGTIELVKALDRDPPAGVPSWNFVVQAIDDDGNGLVGYAD--VQVNVRDINDNSPIFPERLF-GYIEENREPIHSDGVYFMDVQARDFDDPTTENANIEYGIVRNKL-INGESVFRIDQNTGKIFAMRSLDREISSEREFIIEVRANDRGVPSREGFANVTIKVTDMNDNAPFFEKTRYEGSVEETAPIGAAVMSFSAFDADEEAKDNVFTYQLSEESDYFYVTTDKDSKQSSVGVLRVKQPLDYEDVTQRDGFHLGIRVSDG---RHDAEAAVHVALVDRNDHAPH-IHGATEHRVRE--------DVPRGTSIGRYTATDRDAG 1801 HSP 8 Score: 63.5438 bits (153), Expect = 9.340e-10 Identity = 107/461 (23.21%), Postives = 189/461 (41.00%), Query Frame = 2
Query: 986 GKIYLLKTLDYELYSE--QNFDINVLAIDHGSPQLSDSCIIKVNVTDIND-----NSPVIEIVHSQPIPENEQITDPALKLYVSDYDSIDNDVKCQAEKIGRRLKLEQVEKSSYFIYATEIYDYEKEKNLSLSILCQDSGKEPRYTKQLLTIFIKDV--NDNRPKFLRSFYRKSINEDQEKLKPFTKVQALD----KDSDDFGKVKYSIG----LKDRKYFSIDEISGEVRLANEIDRETKDFYNVSVIATDGGGLKDYSYIEISIL--DVNDNYPKL-KSGSSMRVNENLPVGSVVGYISVIDLDLGDNSKVEWTYD---FLGNSSSMLQIENCTVYTSTVLDRESIEHLHIL----ITMVDMGYP-RLTSSATITVSVIDENDNIPKVIYPKTGSLVEEREMDHIAVNSPKYTTVLSIKSFDPDLGINGDVLYHILPSNGSQ-----YFIINQTSGVLK 2269
GKI+LLK L+YE S IN L Q + + I+++V DI++ NSP+ + +P N I + D + D D + I + + T YE+ +S D T QL + I ++ ++ P+F + Y +++ED V+A +D G + YS+ + K+F ID +G + L +D + + + S+++++I DVNDN P + + +V E++P+ + ++ +D D GDNS++ ++ D F NS N + LD + + H + +T D G P L+SSA I + EN N ++ T +A ++ T V+ I++ D D +V Y + NG F I++ +G++K
Sbjct: 376 GKIHLLKPLNYEKTSSIIATVPINGL-------QSTRTQTIRIHVADIDEPPSFVNSPLPMLA---VVPLNPTIGRIVYQFVARD-EHGDGDSNVLYKTIDVIPAGSFIVDPKSGVVRTGWSKYERGDTYRISAQAMDLSPSDNTTSQLSEVAILEILADERPPQFAKQEYEVTVSEDNLVDYSVVDVKAQSFRSFEDGRSKGPITYSLEGDTPEDETKWFRIDPSTGIIHLTRLLDFDDPALPKLHKLKVTAREDNRESHVDLTIRIDDVNDNVPTFTRPLYTAQVREDIPLNQTILKVTAVDKDTGDNSRITYSVDNHNFSINS-------NGEISAKVRLDADQLNERHFVYRFNVTARDHGEPVSLSSSAMIHIRT--ENTNDESAVFLPTSQYTA-----FVAEDAQGGTPVIQIQARDAD---RDEVTYSFMDKNGRSTQKMNLFSIDEHTGLVK 808
BLAST of Protocadherin alpha-2 vs. Ensembl Fly
Match: ds (gene:FBgn0284247 transcript:FBtr0078045) HSP 1 Score: 202.216 bits (513), Expect = 4.445e-52 Identity = 180/630 (28.57%), Postives = 305/630 (48.41%), Query Frame = 2
Query: 446 VKVVIVIEDENDNAPDXXXXXXXXXXXXNDATQLDHNLPKALDKDCPIYGIKNYSL-SGNKVEYFSL---KIRQFQPFLSVKKSFDFENPSEKQFNLSLNAIDNGGKSATLQLIVNVI--DINDNPPIFQKKIVNVTIQENTTFPDAILKLNATDLDSGNNAQISYKFSSINRPII--RETFQLQSETGKIYLLKTLDYELYSEQNFDINVLAIDHGSPQLSDSCIIKVNVTDINDNSPVIEIV-----HSQPIPENEQITDPALKLYVSDYDSIDN--DVKCQAEKIGRRLKLEQVEKSSYFIYATEIYDYEKEKNLSLSILCQDSGKEPRYTKQLLTIFIKDVNDNRPKFLRSFYRKSINEDQEKLKPFTKVQALDKDSDDFGKVKYSIGLKDR---KYFSIDEISGEVRLANEIDRETKDFYNVSVIATDGG--GLKDYSYIEISILDVNDNYPKL-KSGSSMRVNENLPVGSVVGYISVIDLDLGDNSKVEWTYDFLGNSSSMLQIENCT--VYTSTVLDRESIEHLHILITMVDMGYPRLTSSATITVSVIDENDNIPKVIYPK--TGSLVEEREMDHIAVNSPKYTTVLSIKSFDPDLGINGDVLYHILPSNGSQYFIINQTSG 2260
++V++ ++DENDNAP F ++S I EN ++ L A D D Y + Y++ SGN + F L + R +L ++ S + + ++L + A+D G + VN+ D+NDN PIF + T+ EN T ++L++ A+D D+ N + Y +INR + F++ TG IY+ K LD+E +++ ++ V+A DHG L + + + VTD+NDN P I ++ S I E+ Q + ++ V D DS +V L + S Y + D E N +LS++ D G P + + + + I DVNDN P+F + Y ++ E + +V A D+D + YS+ ++F ID +G + + ID ET+ ++V+A DGG L + + ++I DVNDN P +S ++ V EN PVG + +S D D G N+ V +T + ++ + + + + LD E + D G L+++A I + + D NDN P V YP+ SL E + A ++P ++++ + DPD G G V Y I+ N + F I++++G
Sbjct: 158 IRVLVTVKDENDNAPTFPQTSMHIEFPENTPREVKRTLLPARDLDLEPYNTQRYNIVSGNVNDAFRLSSHRERDGVLYLDLQISGFLDRETTPGYSLLIEALDGGTPPLRGFMTVNITIQDVNDNQPIFNQSRYFATVPENATVGTSVLQVYASDTDADENGLVEY---AINRRQSDKEQMFRIDPRTGAIYINKALDFE--TKELHELVVVAKDHGEQPLETTAFVSIRVTDVNDNQPTINVIFLSDDASPKISESAQPGEFVARISVHDPDSKTEYANVNVTLNGGDGHFALTTRDNSIYLVIVHLPLDREIVSNYTLSVVATDKGTPPLHASKSIFLRITDVNDNPPEFEQDLYHANVMEVADPGTSVLQVLAHDRDEGLNSALTYSLAETPETHAQWFQIDPQTGLITTRSHIDCETEPVPQLTVVARDGGVPPLSSTATVLVTIHDVNDNEPIFDQSFYNVSVAENEPVGRCILKVSASDPDCGVNAMVNYTIGEGFKHLTEFEVRSASGEICIAGELDFERRSSYEFPVLATDRG--GLSTTAMIKMQLTDVNDNRP-VFYPREYKVSLRESPKASSQASSTP----IVAVVATDPDYGNFGQVSYRIVAGNEAGIFRIDRSTG 775 HSP 2 Score: 183.726 bits (465), Expect = 2.371e-46 Identity = 193/696 (27.73%), Postives = 316/696 (45.40%), Query Frame = 2
Query: 284 YFRI-SDSGEIRITKVFDRDDVNNVCGPLGCCDKPSCEIVLDIIVTVIPKNERIPVKVVIVIEDENDNAPDXXXXXXXXXXXXNDATQLDHNLPKALDKDCPIYGIKNY---SLSGNKVEY----------FSLKIRQFQPFLSVKKSFDFENPSEKQFNLSLNAIDNG--GKSATLQLIVNVIDINDNPPIFQKKIVNVTIQENTTFPDAILKLNATDLDSGNNAQISYKF---------SSINRPIIRETFQLQSETGKIYLLKTLDYELYSEQNFDINVLAIDHGSPQLSDSCIIKVNVTDINDNSPVIEIVHSQ-PIPENEQITDPALKLYVSDYDSIDN-DVKCQAEKIGRRLKLEQVEKSSYFIYATEIYDYEKEKNLSLSILCQDSGKEPRYTKQLLTIFIKDVNDNRPKFLRSFYR-KSINEDQEKLKPFTKVQALDKDSDDFGKVKYSIGLKDR-----KYFSIDEISGEVRLANEIDRETKDFYNVSVIATDGGG--LKDYSYIEISILDVNDNYPKLKSGSSM-RVNENLPVGSVVGYISVID--LDLGDNS--------KVEWTYDFLG----NSSSMLQIENCTVYTSTVLDRESIEHLHILITMVDMGYPRLTSSATITV--SVIDENDNIPKVIYPKTGSLVEEREMDHIAVNSPKYTTVLSIKSFDPDLGINGDVLYHIL 2215
YF I ++SG IRI K D + +++L+I T+ +V I +ED NDNAP+F +A+ + ++P++ + P+Y + S S +V Y F++ R LS + D+E S ++ L + A D G S L ++V+V D+NDNPP+F+K +V + E+ + I+++NA+DLD+GNNA+I+Y+ +SI+ + + F + +G IYL LD E + + + VLA D+G+P + V V D NDN P + + I EN + + SD D +N ++ I ++ V I E D E + L + +D G R + + I + DVNDN P+ S+ E+Q +V+A+D+D + YSI +K R FSID SG +R +D E + Y + V A+DGG + + + +LD+NDN P S S + RV E+ +G VVG IS I+ D+ NS +V +T + L ++ + + + + +LDRE + I +D S+ ITV V D NDN P+ +P+ ++ E +P T + + + D D G NGD+ Y ++
Sbjct: 874 YFSIETNSGNIRIAKPLDHE--------------AKSQVLLNIQATLGEPPVYGHTQVNIEVEDVNDNAPEF------------EASMVRISVPESAELGAPLYAAHAHDKDSGSSGQVTYSLVKESGKGLFAIDARSGHLILS--QHLDYE--SSQRHTLIVTATDGGVPSLSTNLTILVDVQDVNDNPPVFEKDEYSVNVSESRSINAQIIQVNASDLDTGNNARITYRIVDAGVDNVTNSISSSDVSQHFGIFPNSGWIYLRAPLDRE--TRDRYQLTVLATDNGTPAAHAKTRVIVRVLDANDNDPKFQKSKYEFRIEENLRRGSVVGVVTASDLDLGENAAIRYSLLPINSSFQVHPVTGE---ISTREPLDRELRELYDLVVEARDQGTPVRSARVPVRIHVSDVNDNAPEIADPQEDVVSVREEQPPGTEVVRVRAVDRDHGQNASITYSI-VKGRDSDGHGLFSIDPTSGVIRTRVVLDHEERSIYRLGVAASDGGNPPRETVRMLRVEVLDLNDNRPTFTSSSLVFRVREDAALGHVVGSISPIERPADVVRNSVEESFEDLRVTYTLNPLTKDLIEAAFDIDRHSGNLVVARLLDREVQSEFRLEIRALDTTASNNPQSSAITVKIEVADVNDNAPE--WPQDPIDLQVSEA------TPVGTIIHNFTATDADTGTNGDLQYRLI 1525 HSP 3 Score: 171.014 bits (432), Expect = 1.960e-42 Identity = 158/586 (26.96%), Postives = 266/586 (45.39%), Query Frame = 2
Query: 665 FLSVKKSFDFENPSEKQFNLSLNAIDNG--GKSATLQLIVNVIDINDNPPIFQKKIVNVTIQENTTFPDAILKLNATDLDSGNNAQISYKFSSINRPIIRETFQLQSETGKIYLLKTLDYELYSEQNFDINVLAIDHGSPQLSDSCIIKVNVTDINDNSP--------VIEIVHSQPIPENEQITDPALKLYVSDYDSIDNDVKCQAEKIGR---RLKLEQVEKSSYFIYATEIYDYEKEKNLSLSILCQDSGKEPRYTKQLLTIFIKDVNDNRPKFLRSFYRKSINEDQEKLKPFTKVQALDKDSD-----------DFGKVKYSIG--LKD--RKYFSIDEISGEVRLANEIDRETKDFYNVSVIATDGGGLKDYS----YIEISILDVNDNYPKLKSGS-SMRVNENLPVGSVVGYISVIDLDLGDNSKVEWT----YDFLGNSS----SMLQIENCTVYTS--TVLDRESIEHLHILITMVDMG---YPRLTSSATITVSVIDENDNIPKVIYP-----KTGSLVEEREMDHIAVNSPKYTTVLSIKSFDPDLGINGDVLYHILPSNGSQYFIINQTSGVLK 2269
++ ++ D E + ++ L++ A DNG A ++IV V+D NDN P FQK I+EN + + A+DLD G NA I Y IN +FQ+ TG+I + LD EL + +D+ V A D G+P S ++++V+D+NDN+P V+ + QP P E +++ D D N + GR L ++ +S I + D+E+ L + D G PR T ++L + + D+NDNRP F S + ED + +++ +D D +V Y++ KD F ID SG + +A +DRE + + + + A D + ++I + DVNDN P+ ++V+E PVG+++ + D D G N +++ + L S S+ ++++ T S LD E+++ +++ +D RL +S T+ + ++D ND+ P + P KT SL I+ + V I + D D G NG + Y I NG F IN +G+++
Sbjct: 1104 WIYLRAPLDRE--TRDRYQLTVLATDNGTPAAHAKTRVIVRVLDANDNDPKFQKSKYEFRIEENLRRGSVVGVVTASDLDLGENAAIRYSLLPIN-----SSFQVHPVTGEISTREPLDREL--RELYDLVVEARDQGTPVRSARVPVRIHVSDVNDNAPEIADPQEDVVSVREEQP-PGTE-----VVRVRAVDRDHGQNASITYSIVKGRDSDGHGLFSIDPTSGVIRTRVVLDHEERSIYRLGVAASDGGNPPRETVRMLRVEVLDLNDNRPTFTSSSLVFRVREDAALGHVVGSISPIERPADVVRNSVEESFEDL-RVTYTLNPLTKDLIEAAFDIDRHSGNLVVARLLDREVQSEFRLEIRALDTTASNNPQSSAITVKIEVADVNDNAPEWPQDPIDLQVSEATPVGTIIHNFTATDADTGTNGDLQYRLIRYFPQLNESQEQAMSLFRMDSLTGALSLQAPLDFEAVQEYLLIVQALDQSSNVTERLQTSVTVRLRILDANDHAPHFVSPNSSGGKTASLF-------ISDATRIGEVVAHIVAVDEDSGDNGQLTYEITGGNGEGRFRINSQTGIIE 1666 HSP 4 Score: 147.517 bits (371), Expect = 3.365e-35 Identity = 161/609 (26.44%), Postives = 275/609 (45.16%), Query Frame = 2
Query: 566 ALDKDCPIYGIKNYSLSGN---KVEYFSLKIRQFQPFLSVKKSFDFENPSEKQFNLSLNAIDNGGK--SATLQLIVNVIDINDNPPIFQKKIVNVTIQENTTFPDAILKLNATDLDSGNNAQISYKFSSINRPIIRETFQLQSETGKIYLLKTLDYELYSEQNFDINVLAIDHGSPQLSDSCIIKVNVTDINDNSPVI------EIVHSQPIPENEQITDPALKLYVSDYDSIDNDVKCQAEKIGRRLKLEQVEKSS--YFIYATEIYDYEKEKNLSLSILCQDSGKEPRYTKQLLTIFIKDVNDNRPKFLRSFYRKSINEDQEKLKPFTKVQALDKDSDDFGKVKYSIGLKDR-KYFSIDEISGEVRLANEIDRETKDFYNVSVIATDG-GGLKDYSYIEISILDVNDNYPKLKSGSSMRVN--ENLPVGSVVGYISVIDLDLGDNSKVEWTYDFLGNSSSML---QIENCTVYTSTVLDRESIEHLHILITMVDMGYPRLTSSATITVSVIDENDNIPKVIYPKTGSLVEEREMDHIAVNSPKYTT----VLSIKSFDPDLGINGDVLYHIL------------PSNGSQYFIINQTSGVLKTTWIY 2284
A D+D + YSL+ ++F +I ++ + D E +E L++ A D G S+T ++V + D+NDN PIF + NV++ EN ILK++A+D D G NA ++Y + + F+++S +G+I + LD+E S +++ VLA D G LS + +IK+ +TD+NDN PV + P ++ + P + + +D D + G + ++++S+ F+ ++ + L+I D G ++ + I D P F ++ Y + ED + V A D V+YSI D YFSI+ SG +R+A +D E K +++ AT G + ++ + I + DVNDN P+ ++ S +R++ E+ +G+ + D D G + +V TY + S L + + S LD ES + +++T D G P L+++ TI V V D NDN P E D +VN + + ++ + + D D G N + Y I+ S+ SQ+F I SG WIY
Sbjct: 528 AHDRDEGLNSALTYSLAETPETHAQWF--QIDPQTGLITTRSHIDCE--TEPVPQLTVVARDGGVPPLSSTATVLVTIHDVNDNEPIFDQSFYNVSVAENEPVGRCILKVSASDPDCGVNAMVNYTIGEGFKHLTE--FEVRSASGEICIAGELDFERRS--SYEFPVLATDRGG--LSTTAMIKMQLTDVNDNRPVFYPREYKVSLRESPKASSQASSTPIVAVVATDPDYGNFGQVSYRIVAGNEAGIFRIDRSTGEIFVVRPDMLSVRTQPMHMLNISATDGGNLRSNADAVVFLSIIDAMQRPPIFEKARYNYYVKEDIPRGTVVGSVIAASGDVAHRSPVRYSIYSGDPDGYFSIETNSGNIRIAKPLDHEAKSQVLLNIQATLGEPPVYGHTQVNIEVEDVNDNAPEFEA-SMVRISVPESAELGAPLYAAHAHDKDSGSSGQV--TYSLVKESGKGLFAIDARSGHLILSQHLDYESSQRHTLIVTATDGGVPSLSTNLTILVDVQDVNDNPPVF------------EKDEYSVNVSESRSINAQIIQVNASDLDTGNNARITYRIVDAGVDNVTNSISSSDVSQHFGIFPNSG-----WIY 1106 HSP 5 Score: 132.109 bits (331), Expect = 1.654e-30 Identity = 161/627 (25.68%), Postives = 271/627 (43.22%), Query Frame = 2
Query: 446 VKVVIVIEDENDNAPDXXXXXXXXXXXXN----DATQLDHNLPK--ALDKDCPIYGIKNYSLSGNKVEYFSLKIRQFQPFLSVKKSF-----DFENPSEKQFNLSLNAIDNGG---KSATLQLIVNVIDINDNPPIFQKKIVNVTIQENTTFPDAILKLNATDLDSGNNAQISYKFSS----------INRPIIRETFQLQSETGKIYLL----------KTLDYELYSEQNFDINVLAIDHGSPQLSDSCIIKVNVTDINDNSPVIE--IVHSQPIPENEQITDPAL--KLYVSDYDSIDND---VKCQAEKIGRRLKLEQVEKSSYFIYATEIYDYEKEKNLSLSILCQDSGK-EPRYTKQLLTIFIKDVNDNRPKFLRSFYRKSINEDQEKLKPFTKVQALDKDSDDFGKVKYSIGLKDRKYFSIDEISGEVRLANEIDRETKDFYNVSVIATDGGGLKDYSY---IEISILDVNDNYPKLKSGSSM-RVNENLPVGSVVGYISVIDLDLGDNSKVEWTYDFLGNS-SSMLQIENCT--VYTSTVLDRESIEHLHILITMVDMGYPRLTSSATITVSVIDENDNIPKVIYPKTGSLVEEREMDHIAVNSPKYTTVLSIKSFDPD 2179
V V + I D ND+AP F + + + DAT++ + A+D+D G Y ++G E +I + + KS D E +FNL + A D+G K ++L L + V ++NPP F + + TI EN +L++ A L NA +SY+ + R II Q E+ Y+L TL +Q ++ +G Q D I + V D+NDNSP + +PEN ++P + + SD D N +G + ++ SS + D E+ +L I D G+ + R +TIF++D NDN P+F S Y S+ ED ++ A+D D ++ YS+ + + F+ID SG + ++DRE + YN V+ATDGG + S ++I++LD+NDN P + + +V + G + + +D DLG N+++ ++ + ++ S+ +I T + S L ES + LH+ + D G P +S I + + + P + + V +E NSP T +L + + D
Sbjct: 1586 VTVRLRILDANDHAPHFVSPNSSGGKTASLFISDATRIGEVVAHIVAVDEDSGDNGQLTYEITGGNGE-GRFRINSQTGIIELVKSLPPATEDVEKGG--RFNLIIGAKDHGQPEPKKSSLNLHLIVQGSHNNPPRFLQAVYRATILENVPSGSFVLQVTAKSLHGAENANLSYEIPAGVANDLFHVDWQRGIITTRGQFDRESQASYVLPVYVRDANRQSTLSSSAVRKQRSSDSIGDTSNG--QHFDVATIYITVGDVNDNSPEFRPGSCYGLSVPEN---SEPGVIHTVVASDLDEGPNADLIYSITGGNLGNKFSID----SSSGELSARPLDREQHSRYTLQIQASDRGQPKSRQGHCNITIFVEDQNDNAPRFKLSKYTGSVQEDAPLGTSVVQISAVDADLGVNARLVYSLANETQWQFAIDGQSGLITTVGKLDRELQASYNFMVLATDGGRYEVRSATVPVQINVLDINDNRPIFERYPYIGQVPALIQPGQTLLKVQALDADLGANAEIVYSLNAENSAVSAKFRINPSTGALSASQSLASESGKLLHLEVVARDKGNPPQSSLGLIELLIGEAPQGTPVLRFQNETYRVMLKE------NSPSGTRLLQVVALRSD 2194 HSP 6 Score: 115.546 bits (288), Expect = 2.105e-25 Identity = 99/336 (29.46%), Postives = 162/336 (48.21%), Query Frame = 2
Query: 1331 DYEKEKNLSLSILCQDSGKEPRYTKQLLTIFIKDVNDNRPKFLRSFYRKSINEDQEKLKPFTKVQALDKDSDDFGKVKYSIGLKD---RKYFSIDEISGEVRLANEIDRETKDFYNVSVIATDGG--GLKDYSYIEISILDVNDNYPK-----LKSGSSMRVNENLPVGSVVGYISVIDLDLGDNSKVEWTYDFL----GNSSSMLQIENCTVYTSTV---LDRESIEHLHILITMVDMGYPRLTSSATITVSVIDENDNIPKVIYPKTGSLVEEREMDH---IAVNSPKYTTVLSIKSFDPDLGINGDVLYHIL--PSNGSQYFIINQTSGVLKT 2272
D E SL I D G P + I I+DVNDN+P F +S Y ++ E+ +V A D D+D+ G V+Y+I + + F ID +G + + +D ETK+ + + V+A D G L+ +++ I + DVNDN P L +S +++E+ G V ISV D D SK E+ + G+ L + ++Y V LDRE + + + + D G P L +S +I + + D NDN P+ E+++ H + V P T+VL + + D D G+N + Y + P +Q+F I+ +G++ T
Sbjct: 245 DRETTPGYSLLIEALDGGTPPLRGFMTVNITIQDVNDNQPIFNQSRYFATVPENATVGTSVLQVYASDTDADENGLVEYAINRRQSDKEQMFRIDPRTGAIYINKALDFETKELHELVVVAKDHGEQPLETTAFVSIRVTDVNDNQPTINVIFLSDDASPKISESAQPGEFVARISVHDPD----SKTEYANVNVTLNGGDGHFALTTRDNSIYLVIVHLPLDREIVSNYTLSVVATDKGTPPLHASKSIFLRITDVNDNPPEF----------EQDLYHANVMEVADPG-TSVLQVLAHDRDEGLNSALTYSLAETPETHAQWFQIDPQTGLITT 565 HSP 7 Score: 109.768 bits (273), Expect = 1.131e-23 Identity = 166/671 (24.74%), Postives = 281/671 (41.88%), Query Frame = 2
Query: 446 VKVVIVIEDENDNAPDXXXXXXXXXXXXNDATQLDHNLPKALDKDCPIYG-IKNYSLSGNKVEYFSLKIRQFQPFLS--VKKSFDFENPSEKQFNLSLNAIDNG--GKSATLQLIVNVIDINDNPPIFQKKIVNVTIQENTTFPDAILKLNATDLDSGNNAQISYKFSSINRPIIR--ETFQLQSETGKIYLLKTLDYELYSEQNFDINVLAIDHGSPQLSDSCIIKVNVTDINDNSPVIEIVHSQP------IPENEQITDP------ALKLYVSDYDSIDNDVKC----QAEKIG--------------RRLKLEQVEKSSYFIYATEIYDYEKEKNLSLSILCQDSGKEPRYTKQLLTIFIKDVNDNRPKFLRSFYRKSINEDQEKLKPFTKVQALDKDSDDFGKVKYSIGLKDRKYFSIDEISGEVRLANEIDRETKDFYNVSVIATDGGG--------LKDYSYIEISILDVNDNYPKLKSGS--SMRVNENLPVGSVVGYISVIDLDLGDNSKVEWTYDFL-GNSSSMLQIENCT--VYTSTVLDRES-IEHLHILITMVDMGYPR-LTSSATITVSVIDENDNIPKVIYPKTGSLVEEREMDH-IAVNSPKYTTVLSIKSFDPDLGINGDVLYHI--LPSNGSQY--FIINQTSGVLKTTWIYD 2287
++VI +EDENDN+P FS+ F ++ E + A D D ++ + + GN F + +P S V+ + + + L + A D G + T + V ++D+NDN P F + VT+ E T I ++A D+D+ ++Y+ + + I F L +GK+ L + LDYEL +Q ++++V+A D ++ V V D NDN+PV + QP +P +I++ L + +D DS N+ K + + G RL+ YF+ I+ +D+GK + LL + D R +FL++ YR I+E P V L D + I + F + + S + L +DRE D Y + ++ + G + I+ILD NDN+P + ++E P+ + + ID D + E YD GN M I+ T ++ + LD +S + ++I D + R L S + + DENDN PK +P T E H +A N P ++V + D D G G + Y I PS+ S + F ++ SG++ + +++D
Sbjct: 2306 AELVIELEDENDNSPKFSQKQFVATVSEGNNKGTFVAQVHAFDSDAGSNARLRYHIVDGNHDNAFVI-----EPAFSGIVRTNIVLDREIRDIYKLKIIATDEGVPQMTGTATIRVQIVDVNDNQPTFPPNNL-VTVSEATELGAVITSISANDVDT--YPALTYRLGAESTVDIENMSIFALDRYSGKLVLKRRLDYEL--QQEYELDVIASDAAH---EARTVLTVRVNDENDNAPV--FLAQQPPAYFAILPAISEISESLSVDFDLLTVNATDADSEGNNSKVIYIIEPAQEGFSVHPSNGVVSVNMSRLQPAVSSSGDYFV----------------RIIAKDAGKPALKSSTLLRVQANDNGSGRSQFLQNQYRAQISE----AAPLGSV-VLQLGQDALDQSLAIIAGNEESAFELLQ-SKAIVLVKPLDRERNDLYKLRLVLSHPHGPPLISSLNSSSGISVIITILDANDNFPIFDRSAKYEAEISELAPLRYSIAQLQAIDADQENTPNSEVVYDITSGNDEHMFTIDLVTGVLFVNNRLDYDSGAKSYELIIRACDSHHQRPLCSLQPFRLELHDENDNEPK--FPLT-------EYVHFLAENEPVGSSVFRAHASDLDKGPFGQLNYSIGPAPSDESSWKMFRVDSESGLVTSAFVFD 2930 HSP 8 Score: 99.3673 bits (246), Expect = 1.467e-20 Identity = 142/578 (24.57%), Postives = 241/578 (41.70%), Query Frame = 2
Query: 683 SFDFEN--PSEKQFNLSLNAIDNGGKSATLQLIVNVIDINDNPPIFQKKIVNVTIQENTTFPDAILKLNATDLDSGNNAQISYKFSSINR-----------PIIRETFQLQSETGKIYLLKTLDYELYSEQNFDINVLAIDHGSPQLSDSCIIKVNVTDINDNSPVIEIVHSQPIPENEQITDPALKLYVSDYDSIDNDVKCQAEKIGRRLKLEQVEKSSYFIYATEIY----------DYEKEKNLSLSILCQDSGKEPRYTKQLLTIFIKDVNDNRPKFLR----SFYR--KSINEDQEKLK---PFTKVQALDKDSD-DFGKVKYSIGLKDRKYFSIDEISGEV-----RLANEIDRETKDFYNVSVIATDGG--GLKDYSYIEISILDVNDNYPK-LKSGSSMRVNENLPVGSVVGYISVIDLDLGDNSKVEWTYDFLGNSSSMLQ-IENCTVYTSTVLDRESIEHLHILITMVDMGYP------RLTSSATITVSVIDENDNIPKVIYPKTGSLVEEREMDHIAVNSPKYTTVLSIKSFDPDL--GINGDVLYHILPSNGSQYFIINQTSGVL 2266
SF N P+E + L D ++ +L++ + D NDN P F +K T+ E + +++A D D+G+NA++ Y N I+R L E IY LK ++A D G PQ++ + I+V + D+NDN P P N A +L NDV R V+ + I+A + Y DYE ++ L ++ D+ E R +LT+ + D NDN P FL +++ +I+E E L V A D DS+ + KV Y I ++ FS+ +G V RL + + D++ V +IA D G LK + + + D + L++ +++E P+GSVV L LG ++ + GN S + +++ + LDRE + + + + P +S ++ ++++D NDN P I+ ++ E E+ +A P ++ +++ D D N +V+Y I N F I+ +GVL
Sbjct: 2277 SFALTNSQPNEIRVVLVARTADAPFLASYAELVIELEDENDNSPKFSQKQFVATVSEGNNKGTFVAQVHAFDSDAGSNARLRYHIVDGNHDNAFVIEPAFSGIVRTNIVLDREIRDIYKLK---------------IIATDEGVPQMTGTATIRVQIVDVNDNQPTFP-------PNNLVTVSEATELGAVITSISANDVDTYPALTYRLGAESTVDIENMSIFALDRYSGKLVLKRRLDYELQQEYELDVIASDAAHEAR---TVLTVRVNDENDNAPVFLAQQPPAYFAILPAISEISESLSVDFDLLTVNATDADSEGNNSKVIYIIE-PAQEGFSVHPSNGVVSVNMSRLQPAVS-SSGDYF-VRIIAKDAGKPALKSSTLLRVQANDNGSGRSQFLQNQYRAQISEAAPLGSVV-------LQLGQDALDQSLAIIAGNEESAFELLQSKAIVLVKPLDRERNDLYKLRLVLSHPHGPPLISSLNSSSGISVIITILDANDNFP--IFDRSAKY--EAEISELA---PLRYSIAQLQAIDADQENTPNSEVVYDITSGNDEHMFTIDLVTGVL 2812 HSP 9 Score: 90.1225 bits (222), Expect = 1.039e-17 Identity = 157/658 (23.86%), Postives = 275/658 (41.79%), Query Frame = 2
Query: 419 VIPKNERIP-----VKVVIVIEDENDNAPDXXXXXXXXXXXXNDATQLDHNLPKALDKDCPIYGIKNYSLSGNK---VEYFSL-KIRQFQPFLSVKKSFDFENPSEKQFNLSLNAIDNGGKSATLQLIVNVIDINDNPPIFQKKIVNV---------TIQENTTFPDAILKLNATDLDS-GNNAQISYKFSSINRPIIRETFQLQSETGKIYL-LKTLDYELYSEQNFDINVLAIDHGSPQLSDSCIIKVNVTD-INDNSPVIEIVHSQPIPENEQITDPALKLYVSDYDSIDNDVKCQAEKIGRRLKLEQVEKSSYFIYATEIYDYEKEKNLSLSILCQDSGKEPRYTKQL------LTIFIKDVNDNRPKFLRSF-YRKSINEDQEKLKPFTKVQALDKDSDDF--GKVKYSI-GLKDRKYFSIDEISGEVRLANEIDRET-KDFYNVSVIATDGGGLKDYSYIE---ISILDVNDNYPKLKSGSSMR-VNENLPVGSVVGYISVIDLDLGDNSKVEWTYDFLGNSSSMLQI-----ENCTVYTSTVLDRESIEHLHILITMVDMGYPRLTSSATITVSV-IDENDNIPKVIYPKTGSLVEEREMDHIAVNSPKYTTVLSIKSFDPDLGINGDVLYHILPSNGSQYFIINQTSGVL 2266
+I +E +P + + I D NDN P + ++AT+L + D Y Y L +E S+ + ++ L +K+ D+E ++++ L + A D ++ T+ L V V D NDN P+F + I E+ + +L +NATD DS GNN+++ Y I P +E F + G + + + L + S ++ + ++A D G P L S +++V D + S ++ + I E + L+L D++D + A +L Q S I + D E+ L ++ P + + I I D NDN P F RS Y I+E ++QA+D D ++ +V Y I D F+ID ++G + + N +D ++ Y + + A D + ++ + + D NDN PK + + EN PVGS V DLD G ++ ++ + S ++ E+ V ++ V D E + + + DMG + A++ V V I+ D +T V AV P+ V + + D D G +G V+Y + S +F +N++SG +
Sbjct: 2398 IIATDEGVPQMTGTATIRVQIVDVNDNQP---TFPPNNLVTVSEATELGAVITSISANDVDTYPALTYRLGAESTVDIENMSIFALDRYSGKLVLKRRLDYE--LQQEYELDVIASDAAHEARTV-LTVRVNDENDNAPVFLAQQPPAYFAILPAISEISESLSVDFDLLTVNATDADSEGNNSKVIY----IIEPA-QEGFSVHPSNGVVSVNMSRLQPAVSSSGDYFVRIIAKDAGKPALKSSTLLRVQANDNGSGRSQFLQNQYRAQISEAAPLGSVVLQL---GQDALDQSLAIIAGNEESAFELLQ----SKAIVLVKPLDRERNDLYKLRLVLSHPHGPPLISSLNSSSGISVIITILDANDNFPIFDRSAKYEAEISELAPLRYSIAQLQAIDADQENTPNSEVVYDITSGNDEHMFTIDLVTGVLFVNNRLDYDSGAKSYELIIRACDSHHQRPLCSLQPFRLELHDENDNEPKFPLTEYVHFLAENEPVGSSVFRAHASDLDKGPFGQLNYSIGPAPSDESSWKMFRVDSESGLVTSAFVFDYEQRQRYDMELLASDMGGKK----ASVAVRVEIESRDEFTPQFTERTYRFVLP-----AAVALPQGYVVGQVTATDSDSGPDGRVVYQL--SAPHSHFKVNRSSGAV 3026 HSP 10 Score: 71.2478 bits (173), Expect = 5.945e-12 Identity = 71/247 (28.74%), Postives = 119/247 (48.18%), Query Frame = 2
Query: 425 PKNERIPVKVVIVIEDENDNAPDXXXXXXXXXXXXNDATQLDHNLPKALDKDCPIYGIKNYSLSGNKVEYFSLKIRQFQPFLSVKKSFDFENPSEKQFNLSLNAIDNGG---KSATLQLIVNVIDINDNPPIFQK----KIVNVTIQENTTFPDAILKLNATDLDSGNNAQISYKFSSINRPIIRETFQLQSETGKIYLLKTLDYELYSEQNFDINVLAIDHGSPQLSDSCIIKVNVTDINDNSPVI 1144
PK+ + + I +ED+NDNAP F S +T S+ E+ A+D D + YSL+ F++ + ++ D E + +N + A D G +SAT+ + +NV+DINDN PIF++ V IQ T +LK+ A D D G NA+I Y ++ N + F++ TG + ++L E S + + V+A D G+P S +I++ + + +PV+
Sbjct: 1929 PKSRQGHCNITIFVEDQNDNAPRFKLSKYTGSVQEDAPLGTSVVQISAVDADLGVNARLVYSLANETQWQFAIDGQSG--LITTVGKLDRE--LQASYNFMVLATDGGRYEVRSATVPVQINVLDINDNRPIFERYPYIGQVPALIQPGQT----LLKVQALDADLGANAEIVYSLNAENS-AVSAKFRINPSTGALSASQSLASE--SGKLLHLEVVARDKGNPPQSSLGLIELLIGEAPQGTPVL 2164 HSP 11 Score: 59.6918 bits (143), Expect = 2.210e-8 Identity = 63/237 (26.58%), Postives = 106/237 (44.73%), Query Frame = 2
Query: 1595 FSIDEISGEVRLANEIDRETKDFYNVSVIATDGGGLKDYSYIEISILDVNDNYPKLKSGSSMRVN--ENLPVGSVVGYISVIDLDLGDNSKVEWTYDFLGNSSSMLQIEN---------CTVYTSTVLDRESIEHLHILITMVDMGYPRLTSSATITVSVIDENDNIPKVIYPKTGSLVEEREMDHIAVNSPKYTTVLSIKSFDPDLGINGDVLYHI--LPSNGSQYFIINQTSGVL 2266
+ID +GE+R ++DRET+ Y++ I G ++ + +++ D NDN P +SM + EN P + DLDL + + GN + ++ + + S LDRE+ +LI +D G P L T+ +++ D NDN P I+ ++ R + N+ T+VL + + D D NG V Y I S+ Q F I+ +G +
Sbjct: 123 LAIDRATGEIRTKVKLDRETRASYSLVAIPLSGRNIR----VLVTVKDENDNAPTFPQ-TSMHIEFPENTPREVKRTLLPARDLDLEPYNTQRYNI-VSGNVNDAFRLSSHRERDGVLYLDLQISGFLDRETTPGYSLLIEALDGGTPPLRGFMTVNITIQDVNDNQP--IFNQS------RYFATVPENATVGTSVLQVYASDTDADENGLVEYAINRRQSDKEQMFRIDPRTGAI 345
BLAST of Protocadherin alpha-2 vs. Ensembl Fly
Match: ds (gene:FBgn0284247 transcript:FBtr0343249) HSP 1 Score: 202.216 bits (513), Expect = 4.445e-52 Identity = 180/630 (28.57%), Postives = 305/630 (48.41%), Query Frame = 2
Query: 446 VKVVIVIEDENDNAPDXXXXXXXXXXXXNDATQLDHNLPKALDKDCPIYGIKNYSL-SGNKVEYFSL---KIRQFQPFLSVKKSFDFENPSEKQFNLSLNAIDNGGKSATLQLIVNVI--DINDNPPIFQKKIVNVTIQENTTFPDAILKLNATDLDSGNNAQISYKFSSINRPII--RETFQLQSETGKIYLLKTLDYELYSEQNFDINVLAIDHGSPQLSDSCIIKVNVTDINDNSPVIEIV-----HSQPIPENEQITDPALKLYVSDYDSIDN--DVKCQAEKIGRRLKLEQVEKSSYFIYATEIYDYEKEKNLSLSILCQDSGKEPRYTKQLLTIFIKDVNDNRPKFLRSFYRKSINEDQEKLKPFTKVQALDKDSDDFGKVKYSIGLKDR---KYFSIDEISGEVRLANEIDRETKDFYNVSVIATDGG--GLKDYSYIEISILDVNDNYPKL-KSGSSMRVNENLPVGSVVGYISVIDLDLGDNSKVEWTYDFLGNSSSMLQIENCT--VYTSTVLDRESIEHLHILITMVDMGYPRLTSSATITVSVIDENDNIPKVIYPK--TGSLVEEREMDHIAVNSPKYTTVLSIKSFDPDLGINGDVLYHILPSNGSQYFIINQTSG 2260
++V++ ++DENDNAP F ++S I EN ++ L A D D Y + Y++ SGN + F L + R +L ++ S + + ++L + A+D G + VN+ D+NDN PIF + T+ EN T ++L++ A+D D+ N + Y +INR + F++ TG IY+ K LD+E +++ ++ V+A DHG L + + + VTD+NDN P I ++ S I E+ Q + ++ V D DS +V L + S Y + D E N +LS++ D G P + + + + I DVNDN P+F + Y ++ E + +V A D+D + YS+ ++F ID +G + + ID ET+ ++V+A DGG L + + ++I DVNDN P +S ++ V EN PVG + +S D D G N+ V +T + ++ + + + + LD E + D G L+++A I + + D NDN P V YP+ SL E + A ++P ++++ + DPD G G V Y I+ N + F I++++G
Sbjct: 158 IRVLVTVKDENDNAPTFPQTSMHIEFPENTPREVKRTLLPARDLDLEPYNTQRYNIVSGNVNDAFRLSSHRERDGVLYLDLQISGFLDRETTPGYSLLIEALDGGTPPLRGFMTVNITIQDVNDNQPIFNQSRYFATVPENATVGTSVLQVYASDTDADENGLVEY---AINRRQSDKEQMFRIDPRTGAIYINKALDFE--TKELHELVVVAKDHGEQPLETTAFVSIRVTDVNDNQPTINVIFLSDDASPKISESAQPGEFVARISVHDPDSKTEYANVNVTLNGGDGHFALTTRDNSIYLVIVHLPLDREIVSNYTLSVVATDKGTPPLHASKSIFLRITDVNDNPPEFEQDLYHANVMEVADPGTSVLQVLAHDRDEGLNSALTYSLAETPETHAQWFQIDPQTGLITTRSHIDCETEPVPQLTVVARDGGVPPLSSTATVLVTIHDVNDNEPIFDQSFYNVSVAENEPVGRCILKVSASDPDCGVNAMVNYTIGEGFKHLTEFEVRSASGEICIAGELDFERRSSYEFPVLATDRG--GLSTTAMIKMQLTDVNDNRP-VFYPREYKVSLRESPKASSQASSTP----IVAVVATDPDYGNFGQVSYRIVAGNEAGIFRIDRSTG 775 HSP 2 Score: 183.726 bits (465), Expect = 2.371e-46 Identity = 193/696 (27.73%), Postives = 316/696 (45.40%), Query Frame = 2
Query: 284 YFRI-SDSGEIRITKVFDRDDVNNVCGPLGCCDKPSCEIVLDIIVTVIPKNERIPVKVVIVIEDENDNAPDXXXXXXXXXXXXNDATQLDHNLPKALDKDCPIYGIKNY---SLSGNKVEY----------FSLKIRQFQPFLSVKKSFDFENPSEKQFNLSLNAIDNG--GKSATLQLIVNVIDINDNPPIFQKKIVNVTIQENTTFPDAILKLNATDLDSGNNAQISYKF---------SSINRPIIRETFQLQSETGKIYLLKTLDYELYSEQNFDINVLAIDHGSPQLSDSCIIKVNVTDINDNSPVIEIVHSQ-PIPENEQITDPALKLYVSDYDSIDN-DVKCQAEKIGRRLKLEQVEKSSYFIYATEIYDYEKEKNLSLSILCQDSGKEPRYTKQLLTIFIKDVNDNRPKFLRSFYR-KSINEDQEKLKPFTKVQALDKDSDDFGKVKYSIGLKDR-----KYFSIDEISGEVRLANEIDRETKDFYNVSVIATDGGG--LKDYSYIEISILDVNDNYPKLKSGSSM-RVNENLPVGSVVGYISVID--LDLGDNS--------KVEWTYDFLG----NSSSMLQIENCTVYTSTVLDRESIEHLHILITMVDMGYPRLTSSATITV--SVIDENDNIPKVIYPKTGSLVEEREMDHIAVNSPKYTTVLSIKSFDPDLGINGDVLYHIL 2215
YF I ++SG IRI K D + +++L+I T+ +V I +ED NDNAP+F +A+ + ++P++ + P+Y + S S +V Y F++ R LS + D+E S ++ L + A D G S L ++V+V D+NDNPP+F+K +V + E+ + I+++NA+DLD+GNNA+I+Y+ +SI+ + + F + +G IYL LD E + + + VLA D+G+P + V V D NDN P + + I EN + + SD D +N ++ I ++ V I E D E + L + +D G R + + I + DVNDN P+ S+ E+Q +V+A+D+D + YSI +K R FSID SG +R +D E + Y + V A+DGG + + + +LD+NDN P S S + RV E+ +G VVG IS I+ D+ NS +V +T + L ++ + + + + +LDRE + I +D S+ ITV V D NDN P+ +P+ ++ E +P T + + + D D G NGD+ Y ++
Sbjct: 874 YFSIETNSGNIRIAKPLDHE--------------AKSQVLLNIQATLGEPPVYGHTQVNIEVEDVNDNAPEF------------EASMVRISVPESAELGAPLYAAHAHDKDSGSSGQVTYSLVKESGKGLFAIDARSGHLILS--QHLDYE--SSQRHTLIVTATDGGVPSLSTNLTILVDVQDVNDNPPVFEKDEYSVNVSESRSINAQIIQVNASDLDTGNNARITYRIVDAGVDNVTNSISSSDVSQHFGIFPNSGWIYLRAPLDRE--TRDRYQLTVLATDNGTPAAHAKTRVIVRVLDANDNDPKFQKSKYEFRIEENLRRGSVVGVVTASDLDLGENAAIRYSLLPINSSFQVHPVTGE---ISTREPLDRELRELYDLVVEARDQGTPVRSARVPVRIHVSDVNDNAPEIADPQEDVVSVREEQPPGTEVVRVRAVDRDHGQNASITYSI-VKGRDSDGHGLFSIDPTSGVIRTRVVLDHEERSIYRLGVAASDGGNPPRETVRMLRVEVLDLNDNRPTFTSSSLVFRVREDAALGHVVGSISPIERPADVVRNSVEESFEDLRVTYTLNPLTKDLIEAAFDIDRHSGNLVVARLLDREVQSEFRLEIRALDTTASNNPQSSAITVKIEVADVNDNAPE--WPQDPIDLQVSEA------TPVGTIIHNFTATDADTGTNGDLQYRLI 1525 HSP 3 Score: 171.014 bits (432), Expect = 1.960e-42 Identity = 158/586 (26.96%), Postives = 266/586 (45.39%), Query Frame = 2
Query: 665 FLSVKKSFDFENPSEKQFNLSLNAIDNG--GKSATLQLIVNVIDINDNPPIFQKKIVNVTIQENTTFPDAILKLNATDLDSGNNAQISYKFSSINRPIIRETFQLQSETGKIYLLKTLDYELYSEQNFDINVLAIDHGSPQLSDSCIIKVNVTDINDNSP--------VIEIVHSQPIPENEQITDPALKLYVSDYDSIDNDVKCQAEKIGR---RLKLEQVEKSSYFIYATEIYDYEKEKNLSLSILCQDSGKEPRYTKQLLTIFIKDVNDNRPKFLRSFYRKSINEDQEKLKPFTKVQALDKDSD-----------DFGKVKYSIG--LKD--RKYFSIDEISGEVRLANEIDRETKDFYNVSVIATDGGGLKDYS----YIEISILDVNDNYPKLKSGS-SMRVNENLPVGSVVGYISVIDLDLGDNSKVEWT----YDFLGNSS----SMLQIENCTVYTS--TVLDRESIEHLHILITMVDMG---YPRLTSSATITVSVIDENDNIPKVIYP-----KTGSLVEEREMDHIAVNSPKYTTVLSIKSFDPDLGINGDVLYHILPSNGSQYFIINQTSGVLK 2269
++ ++ D E + ++ L++ A DNG A ++IV V+D NDN P FQK I+EN + + A+DLD G NA I Y IN +FQ+ TG+I + LD EL + +D+ V A D G+P S ++++V+D+NDN+P V+ + QP P E +++ D D N + GR L ++ +S I + D+E+ L + D G PR T ++L + + D+NDNRP F S + ED + +++ +D D +V Y++ KD F ID SG + +A +DRE + + + + A D + ++I + DVNDN P+ ++V+E PVG+++ + D D G N +++ + L S S+ ++++ T S LD E+++ +++ +D RL +S T+ + ++D ND+ P + P KT SL I+ + V I + D D G NG + Y I NG F IN +G+++
Sbjct: 1104 WIYLRAPLDRE--TRDRYQLTVLATDNGTPAAHAKTRVIVRVLDANDNDPKFQKSKYEFRIEENLRRGSVVGVVTASDLDLGENAAIRYSLLPIN-----SSFQVHPVTGEISTREPLDREL--RELYDLVVEARDQGTPVRSARVPVRIHVSDVNDNAPEIADPQEDVVSVREEQP-PGTE-----VVRVRAVDRDHGQNASITYSIVKGRDSDGHGLFSIDPTSGVIRTRVVLDHEERSIYRLGVAASDGGNPPRETVRMLRVEVLDLNDNRPTFTSSSLVFRVREDAALGHVVGSISPIERPADVVRNSVEESFEDL-RVTYTLNPLTKDLIEAAFDIDRHSGNLVVARLLDREVQSEFRLEIRALDTTASNNPQSSAITVKIEVADVNDNAPEWPQDPIDLQVSEATPVGTIIHNFTATDADTGTNGDLQYRLIRYFPQLNESQEQAMSLFRMDSLTGALSLQAPLDFEAVQEYLLIVQALDQSSNVTERLQTSVTVRLRILDANDHAPHFVSPNSSGGKTASLF-------ISDATRIGEVVAHIVAVDEDSGDNGQLTYEITGGNGEGRFRINSQTGIIE 1666 HSP 4 Score: 147.517 bits (371), Expect = 3.365e-35 Identity = 161/609 (26.44%), Postives = 275/609 (45.16%), Query Frame = 2
Query: 566 ALDKDCPIYGIKNYSLSGN---KVEYFSLKIRQFQPFLSVKKSFDFENPSEKQFNLSLNAIDNGGK--SATLQLIVNVIDINDNPPIFQKKIVNVTIQENTTFPDAILKLNATDLDSGNNAQISYKFSSINRPIIRETFQLQSETGKIYLLKTLDYELYSEQNFDINVLAIDHGSPQLSDSCIIKVNVTDINDNSPVI------EIVHSQPIPENEQITDPALKLYVSDYDSIDNDVKCQAEKIGRRLKLEQVEKSS--YFIYATEIYDYEKEKNLSLSILCQDSGKEPRYTKQLLTIFIKDVNDNRPKFLRSFYRKSINEDQEKLKPFTKVQALDKDSDDFGKVKYSIGLKDR-KYFSIDEISGEVRLANEIDRETKDFYNVSVIATDG-GGLKDYSYIEISILDVNDNYPKLKSGSSMRVN--ENLPVGSVVGYISVIDLDLGDNSKVEWTYDFLGNSSSML---QIENCTVYTSTVLDRESIEHLHILITMVDMGYPRLTSSATITVSVIDENDNIPKVIYPKTGSLVEEREMDHIAVNSPKYTT----VLSIKSFDPDLGINGDVLYHIL------------PSNGSQYFIINQTSGVLKTTWIY 2284
A D+D + YSL+ ++F +I ++ + D E +E L++ A D G S+T ++V + D+NDN PIF + NV++ EN ILK++A+D D G NA ++Y + + F+++S +G+I + LD+E S +++ VLA D G LS + +IK+ +TD+NDN PV + P ++ + P + + +D D + G + ++++S+ F+ ++ + L+I D G ++ + I D P F ++ Y + ED + V A D V+YSI D YFSI+ SG +R+A +D E K +++ AT G + ++ + I + DVNDN P+ ++ S +R++ E+ +G+ + D D G + +V TY + S L + + S LD ES + +++T D G P L+++ TI V V D NDN P E D +VN + + ++ + + D D G N + Y I+ S+ SQ+F I SG WIY
Sbjct: 528 AHDRDEGLNSALTYSLAETPETHAQWF--QIDPQTGLITTRSHIDCE--TEPVPQLTVVARDGGVPPLSSTATVLVTIHDVNDNEPIFDQSFYNVSVAENEPVGRCILKVSASDPDCGVNAMVNYTIGEGFKHLTE--FEVRSASGEICIAGELDFERRS--SYEFPVLATDRGG--LSTTAMIKMQLTDVNDNRPVFYPREYKVSLRESPKASSQASSTPIVAVVATDPDYGNFGQVSYRIVAGNEAGIFRIDRSTGEIFVVRPDMLSVRTQPMHMLNISATDGGNLRSNADAVVFLSIIDAMQRPPIFEKARYNYYVKEDIPRGTVVGSVIAASGDVAHRSPVRYSIYSGDPDGYFSIETNSGNIRIAKPLDHEAKSQVLLNIQATLGEPPVYGHTQVNIEVEDVNDNAPEFEA-SMVRISVPESAELGAPLYAAHAHDKDSGSSGQV--TYSLVKESGKGLFAIDARSGHLILSQHLDYESSQRHTLIVTATDGGVPSLSTNLTILVDVQDVNDNPPVF------------EKDEYSVNVSESRSINAQIIQVNASDLDTGNNARITYRIVDAGVDNVTNSISSSDVSQHFGIFPNSG-----WIY 1106 HSP 5 Score: 132.109 bits (331), Expect = 1.654e-30 Identity = 161/627 (25.68%), Postives = 271/627 (43.22%), Query Frame = 2
Query: 446 VKVVIVIEDENDNAPDXXXXXXXXXXXXN----DATQLDHNLPK--ALDKDCPIYGIKNYSLSGNKVEYFSLKIRQFQPFLSVKKSF-----DFENPSEKQFNLSLNAIDNGG---KSATLQLIVNVIDINDNPPIFQKKIVNVTIQENTTFPDAILKLNATDLDSGNNAQISYKFSS----------INRPIIRETFQLQSETGKIYLL----------KTLDYELYSEQNFDINVLAIDHGSPQLSDSCIIKVNVTDINDNSPVIE--IVHSQPIPENEQITDPAL--KLYVSDYDSIDND---VKCQAEKIGRRLKLEQVEKSSYFIYATEIYDYEKEKNLSLSILCQDSGK-EPRYTKQLLTIFIKDVNDNRPKFLRSFYRKSINEDQEKLKPFTKVQALDKDSDDFGKVKYSIGLKDRKYFSIDEISGEVRLANEIDRETKDFYNVSVIATDGGGLKDYSY---IEISILDVNDNYPKLKSGSSM-RVNENLPVGSVVGYISVIDLDLGDNSKVEWTYDFLGNS-SSMLQIENCT--VYTSTVLDRESIEHLHILITMVDMGYPRLTSSATITVSVIDENDNIPKVIYPKTGSLVEEREMDHIAVNSPKYTTVLSIKSFDPD 2179
V V + I D ND+AP F + + + DAT++ + A+D+D G Y ++G E +I + + KS D E +FNL + A D+G K ++L L + V ++NPP F + + TI EN +L++ A L NA +SY+ + R II Q E+ Y+L TL +Q ++ +G Q D I + V D+NDNSP + +PEN ++P + + SD D N +G + ++ SS + D E+ +L I D G+ + R +TIF++D NDN P+F S Y S+ ED ++ A+D D ++ YS+ + + F+ID SG + ++DRE + YN V+ATDGG + S ++I++LD+NDN P + + +V + G + + +D DLG N+++ ++ + ++ S+ +I T + S L ES + LH+ + D G P +S I + + + P + + V +E NSP T +L + + D
Sbjct: 1586 VTVRLRILDANDHAPHFVSPNSSGGKTASLFISDATRIGEVVAHIVAVDEDSGDNGQLTYEITGGNGE-GRFRINSQTGIIELVKSLPPATEDVEKGG--RFNLIIGAKDHGQPEPKKSSLNLHLIVQGSHNNPPRFLQAVYRATILENVPSGSFVLQVTAKSLHGAENANLSYEIPAGVANDLFHVDWQRGIITTRGQFDRESQASYVLPVYVRDANRQSTLSSSAVRKQRSSDSIGDTSNG--QHFDVATIYITVGDVNDNSPEFRPGSCYGLSVPEN---SEPGVIHTVVASDLDEGPNADLIYSITGGNLGNKFSID----SSSGELSARPLDREQHSRYTLQIQASDRGQPKSRQGHCNITIFVEDQNDNAPRFKLSKYTGSVQEDAPLGTSVVQISAVDADLGVNARLVYSLANETQWQFAIDGQSGLITTVGKLDRELQASYNFMVLATDGGRYEVRSATVPVQINVLDINDNRPIFERYPYIGQVPALIQPGQTLLKVQALDADLGANAEIVYSLNAENSAVSAKFRINPSTGALSASQSLASESGKLLHLEVVARDKGNPPQSSLGLIELLIGEAPQGTPVLRFQNETYRVMLKE------NSPSGTRLLQVVALRSD 2194 HSP 6 Score: 115.546 bits (288), Expect = 2.105e-25 Identity = 99/336 (29.46%), Postives = 162/336 (48.21%), Query Frame = 2
Query: 1331 DYEKEKNLSLSILCQDSGKEPRYTKQLLTIFIKDVNDNRPKFLRSFYRKSINEDQEKLKPFTKVQALDKDSDDFGKVKYSIGLKD---RKYFSIDEISGEVRLANEIDRETKDFYNVSVIATDGG--GLKDYSYIEISILDVNDNYPK-----LKSGSSMRVNENLPVGSVVGYISVIDLDLGDNSKVEWTYDFL----GNSSSMLQIENCTVYTSTV---LDRESIEHLHILITMVDMGYPRLTSSATITVSVIDENDNIPKVIYPKTGSLVEEREMDH---IAVNSPKYTTVLSIKSFDPDLGINGDVLYHIL--PSNGSQYFIINQTSGVLKT 2272
D E SL I D G P + I I+DVNDN+P F +S Y ++ E+ +V A D D+D+ G V+Y+I + + F ID +G + + +D ETK+ + + V+A D G L+ +++ I + DVNDN P L +S +++E+ G V ISV D D SK E+ + G+ L + ++Y V LDRE + + + + D G P L +S +I + + D NDN P+ E+++ H + V P T+VL + + D D G+N + Y + P +Q+F I+ +G++ T
Sbjct: 245 DRETTPGYSLLIEALDGGTPPLRGFMTVNITIQDVNDNQPIFNQSRYFATVPENATVGTSVLQVYASDTDADENGLVEYAINRRQSDKEQMFRIDPRTGAIYINKALDFETKELHELVVVAKDHGEQPLETTAFVSIRVTDVNDNQPTINVIFLSDDASPKISESAQPGEFVARISVHDPD----SKTEYANVNVTLNGGDGHFALTTRDNSIYLVIVHLPLDREIVSNYTLSVVATDKGTPPLHASKSIFLRITDVNDNPPEF----------EQDLYHANVMEVADPG-TSVLQVLAHDRDEGLNSALTYSLAETPETHAQWFQIDPQTGLITT 565 HSP 7 Score: 109.768 bits (273), Expect = 1.131e-23 Identity = 166/671 (24.74%), Postives = 281/671 (41.88%), Query Frame = 2
Query: 446 VKVVIVIEDENDNAPDXXXXXXXXXXXXNDATQLDHNLPKALDKDCPIYG-IKNYSLSGNKVEYFSLKIRQFQPFLS--VKKSFDFENPSEKQFNLSLNAIDNG--GKSATLQLIVNVIDINDNPPIFQKKIVNVTIQENTTFPDAILKLNATDLDSGNNAQISYKFSSINRPIIR--ETFQLQSETGKIYLLKTLDYELYSEQNFDINVLAIDHGSPQLSDSCIIKVNVTDINDNSPVIEIVHSQP------IPENEQITDP------ALKLYVSDYDSIDNDVKC----QAEKIG--------------RRLKLEQVEKSSYFIYATEIYDYEKEKNLSLSILCQDSGKEPRYTKQLLTIFIKDVNDNRPKFLRSFYRKSINEDQEKLKPFTKVQALDKDSDDFGKVKYSIGLKDRKYFSIDEISGEVRLANEIDRETKDFYNVSVIATDGGG--------LKDYSYIEISILDVNDNYPKLKSGS--SMRVNENLPVGSVVGYISVIDLDLGDNSKVEWTYDFL-GNSSSMLQIENCT--VYTSTVLDRES-IEHLHILITMVDMGYPR-LTSSATITVSVIDENDNIPKVIYPKTGSLVEEREMDH-IAVNSPKYTTVLSIKSFDPDLGINGDVLYHI--LPSNGSQY--FIINQTSGVLKTTWIYD 2287
++VI +EDENDN+P FS+ F ++ E + A D D ++ + + GN F + +P S V+ + + + L + A D G + T + V ++D+NDN P F + VT+ E T I ++A D+D+ ++Y+ + + I F L +GK+ L + LDYEL +Q ++++V+A D ++ V V D NDN+PV + QP +P +I++ L + +D DS N+ K + + G RL+ YF+ I+ +D+GK + LL + D R +FL++ YR I+E P V L D + I + F + + S + L +DRE D Y + ++ + G + I+ILD NDN+P + ++E P+ + + ID D + E YD GN M I+ T ++ + LD +S + ++I D + R L S + + DENDN PK +P T E H +A N P ++V + D D G G + Y I PS+ S + F ++ SG++ + +++D
Sbjct: 2306 AELVIELEDENDNSPKFSQKQFVATVSEGNNKGTFVAQVHAFDSDAGSNARLRYHIVDGNHDNAFVI-----EPAFSGIVRTNIVLDREIRDIYKLKIIATDEGVPQMTGTATIRVQIVDVNDNQPTFPPNNL-VTVSEATELGAVITSISANDVDT--YPALTYRLGAESTVDIENMSIFALDRYSGKLVLKRRLDYEL--QQEYELDVIASDAAH---EARTVLTVRVNDENDNAPV--FLAQQPPAYFAILPAISEISESLSVDFDLLTVNATDADSEGNNSKVIYIIEPAQEGFSVHPSNGVVSVNMSRLQPAVSSSGDYFV----------------RIIAKDAGKPALKSSTLLRVQANDNGSGRSQFLQNQYRAQISE----AAPLGSV-VLQLGQDALDQSLAIIAGNEESAFELLQ-SKAIVLVKPLDRERNDLYKLRLVLSHPHGPPLISSLNSSSGISVIITILDANDNFPIFDRSAKYEAEISELAPLRYSIAQLQAIDADQENTPNSEVVYDITSGNDEHMFTIDLVTGVLFVNNRLDYDSGAKSYELIIRACDSHHQRPLCSLQPFRLELHDENDNEPK--FPLT-------EYVHFLAENEPVGSSVFRAHASDLDKGPFGQLNYSIGPAPSDESSWKMFRVDSESGLVTSAFVFD 2930 HSP 8 Score: 99.3673 bits (246), Expect = 1.467e-20 Identity = 142/578 (24.57%), Postives = 241/578 (41.70%), Query Frame = 2
Query: 683 SFDFEN--PSEKQFNLSLNAIDNGGKSATLQLIVNVIDINDNPPIFQKKIVNVTIQENTTFPDAILKLNATDLDSGNNAQISYKFSSINR-----------PIIRETFQLQSETGKIYLLKTLDYELYSEQNFDINVLAIDHGSPQLSDSCIIKVNVTDINDNSPVIEIVHSQPIPENEQITDPALKLYVSDYDSIDNDVKCQAEKIGRRLKLEQVEKSSYFIYATEIY----------DYEKEKNLSLSILCQDSGKEPRYTKQLLTIFIKDVNDNRPKFLR----SFYR--KSINEDQEKLK---PFTKVQALDKDSD-DFGKVKYSIGLKDRKYFSIDEISGEV-----RLANEIDRETKDFYNVSVIATDGG--GLKDYSYIEISILDVNDNYPK-LKSGSSMRVNENLPVGSVVGYISVIDLDLGDNSKVEWTYDFLGNSSSMLQ-IENCTVYTSTVLDRESIEHLHILITMVDMGYP------RLTSSATITVSVIDENDNIPKVIYPKTGSLVEEREMDHIAVNSPKYTTVLSIKSFDPDL--GINGDVLYHILPSNGSQYFIINQTSGVL 2266
SF N P+E + L D ++ +L++ + D NDN P F +K T+ E + +++A D D+G+NA++ Y N I+R L E IY LK ++A D G PQ++ + I+V + D+NDN P P N A +L NDV R V+ + I+A + Y DYE ++ L ++ D+ E R +LT+ + D NDN P FL +++ +I+E E L V A D DS+ + KV Y I ++ FS+ +G V RL + + D++ V +IA D G LK + + + D + L++ +++E P+GSVV L LG ++ + GN S + +++ + LDRE + + + + P +S ++ ++++D NDN P I+ ++ E E+ +A P ++ +++ D D N +V+Y I N F I+ +GVL
Sbjct: 2277 SFALTNSQPNEIRVVLVARTADAPFLASYAELVIELEDENDNSPKFSQKQFVATVSEGNNKGTFVAQVHAFDSDAGSNARLRYHIVDGNHDNAFVIEPAFSGIVRTNIVLDREIRDIYKLK---------------IIATDEGVPQMTGTATIRVQIVDVNDNQPTFP-------PNNLVTVSEATELGAVITSISANDVDTYPALTYRLGAESTVDIENMSIFALDRYSGKLVLKRRLDYELQQEYELDVIASDAAHEAR---TVLTVRVNDENDNAPVFLAQQPPAYFAILPAISEISESLSVDFDLLTVNATDADSEGNNSKVIYIIE-PAQEGFSVHPSNGVVSVNMSRLQPAVS-SSGDYF-VRIIAKDAGKPALKSSTLLRVQANDNGSGRSQFLQNQYRAQISEAAPLGSVV-------LQLGQDALDQSLAIIAGNEESAFELLQSKAIVLVKPLDRERNDLYKLRLVLSHPHGPPLISSLNSSSGISVIITILDANDNFP--IFDRSAKY--EAEISELA---PLRYSIAQLQAIDADQENTPNSEVVYDITSGNDEHMFTIDLVTGVL 2812 HSP 9 Score: 90.1225 bits (222), Expect = 1.039e-17 Identity = 157/658 (23.86%), Postives = 275/658 (41.79%), Query Frame = 2
Query: 419 VIPKNERIP-----VKVVIVIEDENDNAPDXXXXXXXXXXXXNDATQLDHNLPKALDKDCPIYGIKNYSLSGNK---VEYFSL-KIRQFQPFLSVKKSFDFENPSEKQFNLSLNAIDNGGKSATLQLIVNVIDINDNPPIFQKKIVNV---------TIQENTTFPDAILKLNATDLDS-GNNAQISYKFSSINRPIIRETFQLQSETGKIYL-LKTLDYELYSEQNFDINVLAIDHGSPQLSDSCIIKVNVTD-INDNSPVIEIVHSQPIPENEQITDPALKLYVSDYDSIDNDVKCQAEKIGRRLKLEQVEKSSYFIYATEIYDYEKEKNLSLSILCQDSGKEPRYTKQL------LTIFIKDVNDNRPKFLRSF-YRKSINEDQEKLKPFTKVQALDKDSDDF--GKVKYSI-GLKDRKYFSIDEISGEVRLANEIDRET-KDFYNVSVIATDGGGLKDYSYIE---ISILDVNDNYPKLKSGSSMR-VNENLPVGSVVGYISVIDLDLGDNSKVEWTYDFLGNSSSMLQI-----ENCTVYTSTVLDRESIEHLHILITMVDMGYPRLTSSATITVSV-IDENDNIPKVIYPKTGSLVEEREMDHIAVNSPKYTTVLSIKSFDPDLGINGDVLYHILPSNGSQYFIINQTSGVL 2266
+I +E +P + + I D NDN P + ++AT+L + D Y Y L +E S+ + ++ L +K+ D+E ++++ L + A D ++ T+ L V V D NDN P+F + I E+ + +L +NATD DS GNN+++ Y I P +E F + G + + + L + S ++ + ++A D G P L S +++V D + S ++ + I E + L+L D++D + A +L Q S I + D E+ L ++ P + + I I D NDN P F RS Y I+E ++QA+D D ++ +V Y I D F+ID ++G + + N +D ++ Y + + A D + ++ + + D NDN PK + + EN PVGS V DLD G ++ ++ + S ++ E+ V ++ V D E + + + DMG + A++ V V I+ D +T V AV P+ V + + D D G +G V+Y + S +F +N++SG +
Sbjct: 2398 IIATDEGVPQMTGTATIRVQIVDVNDNQP---TFPPNNLVTVSEATELGAVITSISANDVDTYPALTYRLGAESTVDIENMSIFALDRYSGKLVLKRRLDYE--LQQEYELDVIASDAAHEARTV-LTVRVNDENDNAPVFLAQQPPAYFAILPAISEISESLSVDFDLLTVNATDADSEGNNSKVIY----IIEPA-QEGFSVHPSNGVVSVNMSRLQPAVSSSGDYFVRIIAKDAGKPALKSSTLLRVQANDNGSGRSQFLQNQYRAQISEAAPLGSVVLQL---GQDALDQSLAIIAGNEESAFELLQ----SKAIVLVKPLDRERNDLYKLRLVLSHPHGPPLISSLNSSSGISVIITILDANDNFPIFDRSAKYEAEISELAPLRYSIAQLQAIDADQENTPNSEVVYDITSGNDEHMFTIDLVTGVLFVNNRLDYDSGAKSYELIIRACDSHHQRPLCSLQPFRLELHDENDNEPKFPLTEYVHFLAENEPVGSSVFRAHASDLDKGPFGQLNYSIGPAPSDESSWKMFRVDSESGLVTSAFVFDYEQRQRYDMELLASDMGGKK----ASVAVRVEIESRDEFTPQFTERTYRFVLP-----AAVALPQGYVVGQVTATDSDSGPDGRVVYQL--SAPHSHFKVNRSSGAV 3026 HSP 10 Score: 71.2478 bits (173), Expect = 5.945e-12 Identity = 71/247 (28.74%), Postives = 119/247 (48.18%), Query Frame = 2
Query: 425 PKNERIPVKVVIVIEDENDNAPDXXXXXXXXXXXXNDATQLDHNLPKALDKDCPIYGIKNYSLSGNKVEYFSLKIRQFQPFLSVKKSFDFENPSEKQFNLSLNAIDNGG---KSATLQLIVNVIDINDNPPIFQK----KIVNVTIQENTTFPDAILKLNATDLDSGNNAQISYKFSSINRPIIRETFQLQSETGKIYLLKTLDYELYSEQNFDINVLAIDHGSPQLSDSCIIKVNVTDINDNSPVI 1144
PK+ + + I +ED+NDNAP F S +T S+ E+ A+D D + YSL+ F++ + ++ D E + +N + A D G +SAT+ + +NV+DINDN PIF++ V IQ T +LK+ A D D G NA+I Y ++ N + F++ TG + ++L E S + + V+A D G+P S +I++ + + +PV+
Sbjct: 1929 PKSRQGHCNITIFVEDQNDNAPRFKLSKYTGSVQEDAPLGTSVVQISAVDADLGVNARLVYSLANETQWQFAIDGQSG--LITTVGKLDRE--LQASYNFMVLATDGGRYEVRSATVPVQINVLDINDNRPIFERYPYIGQVPALIQPGQT----LLKVQALDADLGANAEIVYSLNAENS-AVSAKFRINPSTGALSASQSLASE--SGKLLHLEVVARDKGNPPQSSLGLIELLIGEAPQGTPVL 2164 HSP 11 Score: 59.6918 bits (143), Expect = 2.210e-8 Identity = 63/237 (26.58%), Postives = 106/237 (44.73%), Query Frame = 2
Query: 1595 FSIDEISGEVRLANEIDRETKDFYNVSVIATDGGGLKDYSYIEISILDVNDNYPKLKSGSSMRVN--ENLPVGSVVGYISVIDLDLGDNSKVEWTYDFLGNSSSMLQIEN---------CTVYTSTVLDRESIEHLHILITMVDMGYPRLTSSATITVSVIDENDNIPKVIYPKTGSLVEEREMDHIAVNSPKYTTVLSIKSFDPDLGINGDVLYHI--LPSNGSQYFIINQTSGVL 2266
+ID +GE+R ++DRET+ Y++ I G ++ + +++ D NDN P +SM + EN P + DLDL + + GN + ++ + + S LDRE+ +LI +D G P L T+ +++ D NDN P I+ ++ R + N+ T+VL + + D D NG V Y I S+ Q F I+ +G +
Sbjct: 123 LAIDRATGEIRTKVKLDRETRASYSLVAIPLSGRNIR----VLVTVKDENDNAPTFPQ-TSMHIEFPENTPREVKRTLLPARDLDLEPYNTQRYNI-VSGNVNDAFRLSSHRERDGVLYLDLQISGFLDRETTPGYSLLIEALDGGTPPLRGFMTVNITIQDVNDNQP--IFNQS------RYFATVPENATVGTSVLQVYASDTDADENGLVEYAINRRQSDKEQMFRIDPRTGAI 345
BLAST of Protocadherin alpha-2 vs. Ensembl Fly
Match: stan (gene:FBgn0024836 transcript:FBtr0304899) HSP 1 Score: 183.341 bits (464), Expect = 3.151e-46 Identity = 168/566 (29.68%), Postives = 258/566 (45.58%), Query Frame = 2
Query: 593 GIKNYSLSGNKVEYFSLKIRQFQPFLSVKKSFDFENPSEKQFNLSLNAIDNGG--KSATLQLIVNVIDINDNPPIFQKKIVNVTIQENTTFPDAILKLNATDLDSGNNAQISYKFSSI--NRPIIRETFQLQSETGKIYLLKTLDYELYSEQNFDINVLAIDHGSPQLSDSCIIKVNVTDINDNSPVIEIVHSQP-IPENEQITDPALKLYVSDYDSIDNDVKCQAEKIGRRLKLEQVEKSSY-FIYATEIYDYEKEKNLSLSILCQDSGKEPRYTKQLLTIFIKDVNDNRPKFLRSFYRKSINEDQEKLKPFTKVQALDKDSDDFGKVKYSI------GLKDRKYFSIDEISGEVRLANEIDRETKDFYNVSVIATDGG--GLKDYSYIEISILDVNDNYPKLKSG-SSMRVNENLPVGSVVGYISVIDLDLGDNSKVEWTYD--FLGNSSSMLQIENCTVYTSTVLDRESIEHLHILITMVDMGYPRLTSSATITVSVIDENDNIPKVIYPKTGSLVEEREMDHIAVNSPKYTTVLSIKSFDPDLGINGDVLYHILPSNGSQYF 2239
I+ + GN FS I +S+ K D+E S + + L + A D G +S T QL+VNVID NDN P F ++ EN I+++ A D D G NA+I+Y S N P+ + TG + +K LD E + F V+A D G P S S + + V D+NDN P + + + E++ P + +D D D+ + + R + ++ I + DY++EK L++ DSG R + I I D N+ P F + Y S+ ED V A D D ++ YS+ GL FSI+ +G + +DRET Y ++V A DGG L D + +EI + DVNDN P KS + E+ VG+ V ++ D D+G N ++++ + + S ++ + T+ T+ LDRES+ H+ VD G P L+S+ + + + D ND+ P K V E NSP + V I + DPD G+N V Y I+ + S F
Sbjct: 618 AIRYAIIGGNTQSQFS--IDSMSGDVSLVKPLDYE--SVRSYRLVIRAQDGGSPSRSNTTQLLVNVIDANDNAPRFYTSQFQESVLENVPVGYNIIRVQAYDSDEGANAEITYSISERDDNFPLA-----VDPRTGWVQTIKPLDRE--EQGRFAFQVVAKDGGVPPKSASSSVVITVQDVNDNDPAFNPKYYEANVGEDQPPGTPVTTVTATDPDE-DSRLHYEITTGNTRGRFAITSQNGRGLITIAQSLDYKQEKRFLLTVAATDSGG--RSDTATVHINITDANNFAPIFENAPYSASVFEDAPVGTTVLVVSATDSDVGVNAQITYSLNEESINGLGSPDPFSINPQTGAIVTNAPLDRETTSGYLLTVTAKDGGNPSLSDTTDVEIGVTDVNDNAPAFKSPLYQASILEDALVGTSVIQVAASDPDVGLNGRIKYLLSDRDIEDGSFVIDPTSGTIRTNKGLDRESVAVFHLTAIAVDKGSPPLSSTVEVQIRLEDVNDSPPTFASDKITLYVPE--------NSPVGSVVGEIHAHDPDEGVNAVVHYSIIGGDDSNAF 1161 HSP 2 Score: 142.124 bits (357), Expect = 1.474e-33 Identity = 135/514 (26.26%), Postives = 233/514 (45.33%), Query Frame = 2
Query: 752 KSATLQLIVNVIDINDNPPIFQKKIVNVTIQENTTFPDAILKLNATDLDSGNNAQISYKFSSIN----------RPIIRETFQLQSETGKIYLLKTLDYELYSEQNFDINVLAIDHGSPQ---LSDSCIIKVNVTDINDNSPVI-EIVHSQPIPENEQIT---DPALKLYVSDYDSIDNDVKCQAEKIGRRLKLEQVEKSSYFIYATEIYDYEKEKNLSLSILCQDSGKEPRYTKQLLTIFIKDVNDNRPKFLRSFYRKSINEDQEKLKPFTKVQALDKDSDDFGKVKYSIGLKDRKY-FSIDEISGEVRLANEIDRETKDFYNVSVIATDGG--GLKDYSYIEISILDVNDNYPKLKSG-SSMRVNENLPVGSVVGYISVIDLDLGDNSKVEW---TYDFLGNSSSMLQIENCTVYTSTVLDRESIEHLHILITMVDMGYPRLTSSATITVSVIDENDNIPKVIY---PKTGSLVEEREMDHIAVNSPKYTTVLSIKSFDPDLGINGDVLYHI 2212
+S T L VNV+D ND+ P F+ + +I+E T ++ L ATD D G NA+I Y ++ PI F++ S +G I +LD E + ++ + V A D S Q + + ++V V D NDN P E ++ +PE++ + + +D D +N A G ++ S + + DYE ++ L I QD G R L + + D NDN P+F S +++S+ E+ +VQA D D ++ YSI +D + ++D +G V+ +DRE + + V+A DGG S + I++ DVNDN P V E+ P G+ V ++ D D ++S++ + T + G + Q + + LD + + + + D G + +AT+ +++ D N+ P I+ P + S+ E+ +P TTVL + + D D+G+N + Y +
Sbjct: 444 RSGTTTLQVNVLDCNDHSPTFEAEQFEASIREGATVGSTVITLRATDQDIGKNAEIEYGIEAVTDGAGLAQDQEMPI----FRIDSRSGVISTRSSLDRE--TSDSYHLLVTAADLASAQSERRTATASVQVKVLDDNDNYPQFSERTYTVQVPEDQWGGTEDNTVAHIRATDADQGNNAAIRYAIIGGNTQSQFSIDSMSGDVSLVKPLDYESVRSYRLVIRAQDGGSPSRSNTTQLLVNVIDANDNAPRFYTSQFQESVLENVPVGYNIIRVQAYDSDEGANAEITYSISERDDNFPLAVDPRTGWVQTIKPLDREEQGRFAFQVVAKDGGVPPKSASSSVVITVQDVNDNDPAFNPKYYEANVGEDQPPGTPVTTVTATDPD--EDSRLHYEITTGNTRGRFAITSQNGRGLITIAQSLDYKQEKRFLLTVAATDSG--GRSDTATVHINITDANNFAP--IFENAPYSASVFED---------APVGTTVLVVSATDSDVGVNAQITYSL 936 HSP 3 Score: 135.576 bits (340), Expect = 1.416e-31 Identity = 144/521 (27.64%), Postives = 241/521 (46.26%), Query Frame = 2
Query: 419 VIPKNERIPVK-----VVIVIEDENDNAPDXXXXXXXXXXXXNDATQLDHNLPKALDKDCPIYGIKNYSLS-GNKVEYFSLKIRQFQPFLSVKKSFDFENPSEKQFNLSLNAIDNGGKSATLQLIVNVIDINDNPPIFQKKIVNVTIQENTTFPDAILKLNATDLDSGNNAQISYKFS--SINRPIIRETFQLQSETGKIYLLKTLDYELYSEQNFDINVLAIDHGSPQLSDSCIIKVNVTDINDNSPVIEIVHSQPIPENEQITDPALKLYVSDYDSIDNDVKCQAEKIGRRLKLEQVEKSSYFIYAT-------EIYDYEKEKNLSLSILCQDSGKEPRYTKQLLTIFIKDVNDNRPKFLRSFYRKSINEDQEKLKPFTKVQALDKDSDDFGKVKYS-IGLKDRKYFSIDEISGEVRLA----NEIDRETKDFYNVSVIATDGGGLKDYSYIEISILDVNDNYPKLKSGSSMRVN--ENLPVGSVVGYISVIDLDLGDNSKVEWTYDFL-GNSSSMLQI 1912
V+ K+ +P K VVI ++D NDN P F+ + ++ E+ A D D +Y ++ GN F++ + + +++ +S D++ EK+F L++ A D+GG+S T + +N+ D N+ PIF+ + ++ E+ +L ++ATD D G NAQI+Y + SIN + F + +TG I LD E S + + V A D G+P LSD+ +++ VTD+NDN+P + P+ + + D + V + D DV +I L +E S+ I T + D E L+ + D G P + + I ++DVND+ P F + E+ ++ A D D V YS IG D FS+ G R E+D E+ V+ L++ ++IEI + DVNDN P L+ + N ++ P G +G I D D+ D + Y L GN++++L++
Sbjct: 764 VVAKDGGVPPKSASSSVVITVQDVNDNDPAFNPKYYEANVGEDQPPGTPVTTVTATDPD--EDSRLHYEITTGNTRGRFAITSQNGRGLITIAQSLDYKQ--EKRFLLTVAATDSGGRSDTATVHINITDANNFAPIFENAPYSASVFEDAPVGTTVLVVSATDSDVGVNAQITYSLNEESINGLGSPDPFSINPQTGAIVTNAPLDRETTS--GYLLTVTAKDGGNPSLSDTTDVEIGVTDVNDNAPAFK----SPLYQASILEDALVGTSVIQVAASDPDVGLNG-RIKYLLSDRDIEDGSFVIDPTSGTIRTNKGLDRESVAVFHLTAIAVDKGSPPLSSTVEVQIRLEDVNDSPPTFASDKITLYVPENSPVGSVVGEIHAHDPDEGVNAVVHYSIIGGDDSNAFSLVTRPGSERAQLLTMTELDYESTRKRFELVVRAASPPLRNDAHIEILVTDVNDNAPVLRDFQVIFNNFRDHFPSGE-IGRIPAFDADVSD----KLHYRILSGNNANLLRL 1268 HSP 4 Score: 122.094 bits (305), Expect = 1.873e-27 Identity = 126/514 (24.51%), Postives = 223/514 (43.39%), Query Frame = 2
Query: 788 DINDNPPIFQKKIVNVTIQENTTFPDAILKLNATDLDSGNNAQISYKFSSINRPIIRETFQLQSETGKIYLLKTLDYELYSEQNFDINVLAIDHGSPQLSDSCIIKVNVTDINDNSPVIEIVHSQP-IPENEQITDPALKLYVSDYD-----SIDNDVKCQAEKIG----RRLKLEQVEKSSYFIYATEIYDYEKEKNLSLSILCQD---SGKEPRYTKQLLTIFIKDVNDNRPKFLRSFYRKSINEDQ---EKLKPFTKVQALDKDSDDFGKVKYS-IGLKDRKYFSIDEISGEVRLANEIDRETKDFYNVSVIATDGG--GLKDYSYIEISILDVNDNYPKL-KSGSSMRVNENLPVGSVVGYISVIDLDLGDNSKVEWTYDFLGNSSSM-LQIENCTVYTSTV--LDRESIEHLHILITMVDMGYPRLTSSATITVSVIDENDNIPKVIYPKTGSLVEEREMDHIAVNSPKYTTVLSIKSFDPDLGINGDVLYHILPSNGSQYFIINQTSG 2260
++ + P F++ + ++ E A+ + A D + ++ + Y S+ + F++ S TG + +LD EL F V+A D P S + ++VNV D ND+SP E + I E + + L +D D I+ ++ + G + + + +++ S I D E + L + D + E R + + + D NDN P+F Y + EDQ + ++A D D + ++Y+ IG + FSID +SG+V L +D E+ Y + + A DGG + + + ++++D NDN P+ S V EN+PVG + + D D G N+++ TY + L ++ T + T+ LDRE + D G P ++S+++ ++V D NDN P PK ++ + P T V ++ + DPD + + Y I N F I +G
Sbjct: 351 ELRNQSPYFEQALYVASVLEEQPAGAAVTTVRARDPE---DSPVVYSMVSLLDSRSQSLFKVDSRTGVVTTSASLDRELMDVHYF--RVVATDDSFPPRSGTTTLQVNVLDCNDHSPTFEAEQFEASIREGATVGSTVITLRATDQDIGKNAEIEYGIEAVTDGAGLAQDQEMPIFRIDSRSGVISTRSSLDRETSDSYHLLVTAADLASAQSERRTATASVQVKVLDDNDNYPQFSERTYTVQVPEDQWGGTEDNTVAHIRATDADQGNNAAIRYAIIGGNTQSQFSIDSMSGDVSLVKPLDYESVRSYRLVIRAQDGGSPSRSNTTQLLVNVIDANDNAPRFYTSQFQESVLENVPVGYNIIRVQAYDSDEGANAEI--TYSISERDDNFPLAVDPRTGWVQTIKPLDREEQGRFAFQVVAKDGGVPPKSASSSVVITVQDVNDNDP-AFNPKYYEA-------NVGEDQPPGTPVTTVTATDPDE--DSRLHYEITTGNTRGRFAITSQNG 847
BLAST of Protocadherin alpha-2 vs. Ensembl Fly
Match: stan (gene:FBgn0024836 transcript:FBtr0300578) HSP 1 Score: 183.341 bits (464), Expect = 3.151e-46 Identity = 168/566 (29.68%), Postives = 258/566 (45.58%), Query Frame = 2
Query: 593 GIKNYSLSGNKVEYFSLKIRQFQPFLSVKKSFDFENPSEKQFNLSLNAIDNGG--KSATLQLIVNVIDINDNPPIFQKKIVNVTIQENTTFPDAILKLNATDLDSGNNAQISYKFSSI--NRPIIRETFQLQSETGKIYLLKTLDYELYSEQNFDINVLAIDHGSPQLSDSCIIKVNVTDINDNSPVIEIVHSQP-IPENEQITDPALKLYVSDYDSIDNDVKCQAEKIGRRLKLEQVEKSSY-FIYATEIYDYEKEKNLSLSILCQDSGKEPRYTKQLLTIFIKDVNDNRPKFLRSFYRKSINEDQEKLKPFTKVQALDKDSDDFGKVKYSI------GLKDRKYFSIDEISGEVRLANEIDRETKDFYNVSVIATDGG--GLKDYSYIEISILDVNDNYPKLKSG-SSMRVNENLPVGSVVGYISVIDLDLGDNSKVEWTYD--FLGNSSSMLQIENCTVYTSTVLDRESIEHLHILITMVDMGYPRLTSSATITVSVIDENDNIPKVIYPKTGSLVEEREMDHIAVNSPKYTTVLSIKSFDPDLGINGDVLYHILPSNGSQYF 2239
I+ + GN FS I +S+ K D+E S + + L + A D G +S T QL+VNVID NDN P F ++ EN I+++ A D D G NA+I+Y S N P+ + TG + +K LD E + F V+A D G P S S + + V D+NDN P + + + E++ P + +D D D+ + + R + ++ I + DY++EK L++ DSG R + I I D N+ P F + Y S+ ED V A D D ++ YS+ GL FSI+ +G + +DRET Y ++V A DGG L D + +EI + DVNDN P KS + E+ VG+ V ++ D D+G N ++++ + + S ++ + T+ T+ LDRES+ H+ VD G P L+S+ + + + D ND+ P K V E NSP + V I + DPD G+N V Y I+ + S F
Sbjct: 618 AIRYAIIGGNTQSQFS--IDSMSGDVSLVKPLDYE--SVRSYRLVIRAQDGGSPSRSNTTQLLVNVIDANDNAPRFYTSQFQESVLENVPVGYNIIRVQAYDSDEGANAEITYSISERDDNFPLA-----VDPRTGWVQTIKPLDRE--EQGRFAFQVVAKDGGVPPKSASSSVVITVQDVNDNDPAFNPKYYEANVGEDQPPGTPVTTVTATDPDE-DSRLHYEITTGNTRGRFAITSQNGRGLITIAQSLDYKQEKRFLLTVAATDSGG--RSDTATVHINITDANNFAPIFENAPYSASVFEDAPVGTTVLVVSATDSDVGVNAQITYSLNEESINGLGSPDPFSINPQTGAIVTNAPLDRETTSGYLLTVTAKDGGNPSLSDTTDVEIGVTDVNDNAPAFKSPLYQASILEDALVGTSVIQVAASDPDVGLNGRIKYLLSDRDIEDGSFVIDPTSGTIRTNKGLDRESVAVFHLTAIAVDKGSPPLSSTVEVQIRLEDVNDSPPTFASDKITLYVPE--------NSPVGSVVGEIHAHDPDEGVNAVVHYSIIGGDDSNAF 1161 HSP 2 Score: 142.124 bits (357), Expect = 1.474e-33 Identity = 135/514 (26.26%), Postives = 233/514 (45.33%), Query Frame = 2
Query: 752 KSATLQLIVNVIDINDNPPIFQKKIVNVTIQENTTFPDAILKLNATDLDSGNNAQISYKFSSIN----------RPIIRETFQLQSETGKIYLLKTLDYELYSEQNFDINVLAIDHGSPQ---LSDSCIIKVNVTDINDNSPVI-EIVHSQPIPENEQIT---DPALKLYVSDYDSIDNDVKCQAEKIGRRLKLEQVEKSSYFIYATEIYDYEKEKNLSLSILCQDSGKEPRYTKQLLTIFIKDVNDNRPKFLRSFYRKSINEDQEKLKPFTKVQALDKDSDDFGKVKYSIGLKDRKY-FSIDEISGEVRLANEIDRETKDFYNVSVIATDGG--GLKDYSYIEISILDVNDNYPKLKSG-SSMRVNENLPVGSVVGYISVIDLDLGDNSKVEW---TYDFLGNSSSMLQIENCTVYTSTVLDRESIEHLHILITMVDMGYPRLTSSATITVSVIDENDNIPKVIY---PKTGSLVEEREMDHIAVNSPKYTTVLSIKSFDPDLGINGDVLYHI 2212
+S T L VNV+D ND+ P F+ + +I+E T ++ L ATD D G NA+I Y ++ PI F++ S +G I +LD E + ++ + V A D S Q + + ++V V D NDN P E ++ +PE++ + + +D D +N A G ++ S + + DYE ++ L I QD G R L + + D NDN P+F S +++S+ E+ +VQA D D ++ YSI +D + ++D +G V+ +DRE + + V+A DGG S + I++ DVNDN P V E+ P G+ V ++ D D ++S++ + T + G + Q + + LD + + + + D G + +AT+ +++ D N+ P I+ P + S+ E+ +P TTVL + + D D+G+N + Y +
Sbjct: 444 RSGTTTLQVNVLDCNDHSPTFEAEQFEASIREGATVGSTVITLRATDQDIGKNAEIEYGIEAVTDGAGLAQDQEMPI----FRIDSRSGVISTRSSLDRE--TSDSYHLLVTAADLASAQSERRTATASVQVKVLDDNDNYPQFSERTYTVQVPEDQWGGTEDNTVAHIRATDADQGNNAAIRYAIIGGNTQSQFSIDSMSGDVSLVKPLDYESVRSYRLVIRAQDGGSPSRSNTTQLLVNVIDANDNAPRFYTSQFQESVLENVPVGYNIIRVQAYDSDEGANAEITYSISERDDNFPLAVDPRTGWVQTIKPLDREEQGRFAFQVVAKDGGVPPKSASSSVVITVQDVNDNDPAFNPKYYEANVGEDQPPGTPVTTVTATDPD--EDSRLHYEITTGNTRGRFAITSQNGRGLITIAQSLDYKQEKRFLLTVAATDSG--GRSDTATVHINITDANNFAP--IFENAPYSASVFED---------APVGTTVLVVSATDSDVGVNAQITYSL 936 HSP 3 Score: 135.576 bits (340), Expect = 1.416e-31 Identity = 144/521 (27.64%), Postives = 241/521 (46.26%), Query Frame = 2
Query: 419 VIPKNERIPVK-----VVIVIEDENDNAPDXXXXXXXXXXXXNDATQLDHNLPKALDKDCPIYGIKNYSLS-GNKVEYFSLKIRQFQPFLSVKKSFDFENPSEKQFNLSLNAIDNGGKSATLQLIVNVIDINDNPPIFQKKIVNVTIQENTTFPDAILKLNATDLDSGNNAQISYKFS--SINRPIIRETFQLQSETGKIYLLKTLDYELYSEQNFDINVLAIDHGSPQLSDSCIIKVNVTDINDNSPVIEIVHSQPIPENEQITDPALKLYVSDYDSIDNDVKCQAEKIGRRLKLEQVEKSSYFIYAT-------EIYDYEKEKNLSLSILCQDSGKEPRYTKQLLTIFIKDVNDNRPKFLRSFYRKSINEDQEKLKPFTKVQALDKDSDDFGKVKYS-IGLKDRKYFSIDEISGEVRLA----NEIDRETKDFYNVSVIATDGGGLKDYSYIEISILDVNDNYPKLKSGSSMRVN--ENLPVGSVVGYISVIDLDLGDNSKVEWTYDFL-GNSSSMLQI 1912
V+ K+ +P K VVI ++D NDN P F+ + ++ E+ A D D +Y ++ GN F++ + + +++ +S D++ EK+F L++ A D+GG+S T + +N+ D N+ PIF+ + ++ E+ +L ++ATD D G NAQI+Y + SIN + F + +TG I LD E S + + V A D G+P LSD+ +++ VTD+NDN+P + P+ + + D + V + D DV +I L +E S+ I T + D E L+ + D G P + + I ++DVND+ P F + E+ ++ A D D V YS IG D FS+ G R E+D E+ V+ L++ ++IEI + DVNDN P L+ + N ++ P G +G I D D+ D + Y L GN++++L++
Sbjct: 764 VVAKDGGVPPKSASSSVVITVQDVNDNDPAFNPKYYEANVGEDQPPGTPVTTVTATDPD--EDSRLHYEITTGNTRGRFAITSQNGRGLITIAQSLDYKQ--EKRFLLTVAATDSGGRSDTATVHINITDANNFAPIFENAPYSASVFEDAPVGTTVLVVSATDSDVGVNAQITYSLNEESINGLGSPDPFSINPQTGAIVTNAPLDRETTS--GYLLTVTAKDGGNPSLSDTTDVEIGVTDVNDNAPAFK----SPLYQASILEDALVGTSVIQVAASDPDVGLNG-RIKYLLSDRDIEDGSFVIDPTSGTIRTNKGLDRESVAVFHLTAIAVDKGSPPLSSTVEVQIRLEDVNDSPPTFASDKITLYVPENSPVGSVVGEIHAHDPDEGVNAVVHYSIIGGDDSNAFSLVTRPGSERAQLLTMTELDYESTRKRFELVVRAASPPLRNDAHIEILVTDVNDNAPVLRDFQVIFNNFRDHFPSGE-IGRIPAFDADVSD----KLHYRILSGNNANLLRL 1268 HSP 4 Score: 122.094 bits (305), Expect = 1.873e-27 Identity = 126/514 (24.51%), Postives = 223/514 (43.39%), Query Frame = 2
Query: 788 DINDNPPIFQKKIVNVTIQENTTFPDAILKLNATDLDSGNNAQISYKFSSINRPIIRETFQLQSETGKIYLLKTLDYELYSEQNFDINVLAIDHGSPQLSDSCIIKVNVTDINDNSPVIEIVHSQP-IPENEQITDPALKLYVSDYD-----SIDNDVKCQAEKIG----RRLKLEQVEKSSYFIYATEIYDYEKEKNLSLSILCQD---SGKEPRYTKQLLTIFIKDVNDNRPKFLRSFYRKSINEDQ---EKLKPFTKVQALDKDSDDFGKVKYS-IGLKDRKYFSIDEISGEVRLANEIDRETKDFYNVSVIATDGG--GLKDYSYIEISILDVNDNYPKL-KSGSSMRVNENLPVGSVVGYISVIDLDLGDNSKVEWTYDFLGNSSSM-LQIENCTVYTSTV--LDRESIEHLHILITMVDMGYPRLTSSATITVSVIDENDNIPKVIYPKTGSLVEEREMDHIAVNSPKYTTVLSIKSFDPDLGINGDVLYHILPSNGSQYFIINQTSG 2260
++ + P F++ + ++ E A+ + A D + ++ + Y S+ + F++ S TG + +LD EL F V+A D P S + ++VNV D ND+SP E + I E + + L +D D I+ ++ + G + + + +++ S I D E + L + D + E R + + + D NDN P+F Y + EDQ + ++A D D + ++Y+ IG + FSID +SG+V L +D E+ Y + + A DGG + + + ++++D NDN P+ S V EN+PVG + + D D G N+++ TY + L ++ T + T+ LDRE + D G P ++S+++ ++V D NDN P PK ++ + P T V ++ + DPD + + Y I N F I +G
Sbjct: 351 ELRNQSPYFEQALYVASVLEEQPAGAAVTTVRARDPE---DSPVVYSMVSLLDSRSQSLFKVDSRTGVVTTSASLDRELMDVHYF--RVVATDDSFPPRSGTTTLQVNVLDCNDHSPTFEAEQFEASIREGATVGSTVITLRATDQDIGKNAEIEYGIEAVTDGAGLAQDQEMPIFRIDSRSGVISTRSSLDRETSDSYHLLVTAADLASAQSERRTATASVQVKVLDDNDNYPQFSERTYTVQVPEDQWGGTEDNTVAHIRATDADQGNNAAIRYAIIGGNTQSQFSIDSMSGDVSLVKPLDYESVRSYRLVIRAQDGGSPSRSNTTQLLVNVIDANDNAPRFYTSQFQESVLENVPVGYNIIRVQAYDSDEGANAEI--TYSISERDDNFPLAVDPRTGWVQTIKPLDREEQGRFAFQVVAKDGGVPPKSASSSVVITVQDVNDNDP-AFNPKYYEA-------NVGEDQPPGTPVTTVTATDPDE--DSRLHYEITTGNTRGRFAITSQNG 847
BLAST of Protocadherin alpha-2 vs. Ensembl Fly
Match: stan (gene:FBgn0024836 transcript:FBtr0304900) HSP 1 Score: 183.341 bits (464), Expect = 3.347e-46 Identity = 168/566 (29.68%), Postives = 258/566 (45.58%), Query Frame = 2
Query: 593 GIKNYSLSGNKVEYFSLKIRQFQPFLSVKKSFDFENPSEKQFNLSLNAIDNGG--KSATLQLIVNVIDINDNPPIFQKKIVNVTIQENTTFPDAILKLNATDLDSGNNAQISYKFSSI--NRPIIRETFQLQSETGKIYLLKTLDYELYSEQNFDINVLAIDHGSPQLSDSCIIKVNVTDINDNSPVIEIVHSQP-IPENEQITDPALKLYVSDYDSIDNDVKCQAEKIGRRLKLEQVEKSSY-FIYATEIYDYEKEKNLSLSILCQDSGKEPRYTKQLLTIFIKDVNDNRPKFLRSFYRKSINEDQEKLKPFTKVQALDKDSDDFGKVKYSI------GLKDRKYFSIDEISGEVRLANEIDRETKDFYNVSVIATDGG--GLKDYSYIEISILDVNDNYPKLKSG-SSMRVNENLPVGSVVGYISVIDLDLGDNSKVEWTYD--FLGNSSSMLQIENCTVYTSTVLDRESIEHLHILITMVDMGYPRLTSSATITVSVIDENDNIPKVIYPKTGSLVEEREMDHIAVNSPKYTTVLSIKSFDPDLGINGDVLYHILPSNGSQYF 2239
I+ + GN FS I +S+ K D+E S + + L + A D G +S T QL+VNVID NDN P F ++ EN I+++ A D D G NA+I+Y S N P+ + TG + +K LD E + F V+A D G P S S + + V D+NDN P + + + E++ P + +D D D+ + + R + ++ I + DY++EK L++ DSG R + I I D N+ P F + Y S+ ED V A D D ++ YS+ GL FSI+ +G + +DRET Y ++V A DGG L D + +EI + DVNDN P KS + E+ VG+ V ++ D D+G N ++++ + + S ++ + T+ T+ LDRES+ H+ VD G P L+S+ + + + D ND+ P K V E NSP + V I + DPD G+N V Y I+ + S F
Sbjct: 618 AIRYAIIGGNTQSQFS--IDSMSGDVSLVKPLDYE--SVRSYRLVIRAQDGGSPSRSNTTQLLVNVIDANDNAPRFYTSQFQESVLENVPVGYNIIRVQAYDSDEGANAEITYSISERDDNFPLA-----VDPRTGWVQTIKPLDRE--EQGRFAFQVVAKDGGVPPKSASSSVVITVQDVNDNDPAFNPKYYEANVGEDQPPGTPVTTVTATDPDE-DSRLHYEITTGNTRGRFAITSQNGRGLITIAQSLDYKQEKRFLLTVAATDSGG--RSDTATVHINITDANNFAPIFENAPYSASVFEDAPVGTTVLVVSATDSDVGVNAQITYSLNEESINGLGSPDPFSINPQTGAIVTNAPLDRETTSGYLLTVTAKDGGNPSLSDTTDVEIGVTDVNDNAPAFKSPLYQASILEDALVGTSVIQVAASDPDVGLNGRIKYLLSDRDIEDGSFVIDPTSGTIRTNKGLDRESVAVFHLTAIAVDKGSPPLSSTVEVQIRLEDVNDSPPTFASDKITLYVPE--------NSPVGSVVGEIHAHDPDEGVNAVVHYSIIGGDDSNAF 1161 HSP 2 Score: 142.124 bits (357), Expect = 1.438e-33 Identity = 135/514 (26.26%), Postives = 233/514 (45.33%), Query Frame = 2
Query: 752 KSATLQLIVNVIDINDNPPIFQKKIVNVTIQENTTFPDAILKLNATDLDSGNNAQISYKFSSIN----------RPIIRETFQLQSETGKIYLLKTLDYELYSEQNFDINVLAIDHGSPQ---LSDSCIIKVNVTDINDNSPVI-EIVHSQPIPENEQIT---DPALKLYVSDYDSIDNDVKCQAEKIGRRLKLEQVEKSSYFIYATEIYDYEKEKNLSLSILCQDSGKEPRYTKQLLTIFIKDVNDNRPKFLRSFYRKSINEDQEKLKPFTKVQALDKDSDDFGKVKYSIGLKDRKY-FSIDEISGEVRLANEIDRETKDFYNVSVIATDGG--GLKDYSYIEISILDVNDNYPKLKSG-SSMRVNENLPVGSVVGYISVIDLDLGDNSKVEW---TYDFLGNSSSMLQIENCTVYTSTVLDRESIEHLHILITMVDMGYPRLTSSATITVSVIDENDNIPKVIY---PKTGSLVEEREMDHIAVNSPKYTTVLSIKSFDPDLGINGDVLYHI 2212
+S T L VNV+D ND+ P F+ + +I+E T ++ L ATD D G NA+I Y ++ PI F++ S +G I +LD E + ++ + V A D S Q + + ++V V D NDN P E ++ +PE++ + + +D D +N A G ++ S + + DYE ++ L I QD G R L + + D NDN P+F S +++S+ E+ +VQA D D ++ YSI +D + ++D +G V+ +DRE + + V+A DGG S + I++ DVNDN P V E+ P G+ V ++ D D ++S++ + T + G + Q + + LD + + + + D G + +AT+ +++ D N+ P I+ P + S+ E+ +P TTVL + + D D+G+N + Y +
Sbjct: 444 RSGTTTLQVNVLDCNDHSPTFEAEQFEASIREGATVGSTVITLRATDQDIGKNAEIEYGIEAVTDGAGLAQDQEMPI----FRIDSRSGVISTRSSLDRE--TSDSYHLLVTAADLASAQSERRTATASVQVKVLDDNDNYPQFSERTYTVQVPEDQWGGTEDNTVAHIRATDADQGNNAAIRYAIIGGNTQSQFSIDSMSGDVSLVKPLDYESVRSYRLVIRAQDGGSPSRSNTTQLLVNVIDANDNAPRFYTSQFQESVLENVPVGYNIIRVQAYDSDEGANAEITYSISERDDNFPLAVDPRTGWVQTIKPLDREEQGRFAFQVVAKDGGVPPKSASSSVVITVQDVNDNDPAFNPKYYEANVGEDQPPGTPVTTVTATDPD--EDSRLHYEITTGNTRGRFAITSQNGRGLITIAQSLDYKQEKRFLLTVAATDSG--GRSDTATVHINITDANNFAP--IFENAPYSASVFED---------APVGTTVLVVSATDSDVGVNAQITYSL 936 HSP 3 Score: 135.576 bits (340), Expect = 1.428e-31 Identity = 144/521 (27.64%), Postives = 241/521 (46.26%), Query Frame = 2
Query: 419 VIPKNERIPVK-----VVIVIEDENDNAPDXXXXXXXXXXXXNDATQLDHNLPKALDKDCPIYGIKNYSLS-GNKVEYFSLKIRQFQPFLSVKKSFDFENPSEKQFNLSLNAIDNGGKSATLQLIVNVIDINDNPPIFQKKIVNVTIQENTTFPDAILKLNATDLDSGNNAQISYKFS--SINRPIIRETFQLQSETGKIYLLKTLDYELYSEQNFDINVLAIDHGSPQLSDSCIIKVNVTDINDNSPVIEIVHSQPIPENEQITDPALKLYVSDYDSIDNDVKCQAEKIGRRLKLEQVEKSSYFIYAT-------EIYDYEKEKNLSLSILCQDSGKEPRYTKQLLTIFIKDVNDNRPKFLRSFYRKSINEDQEKLKPFTKVQALDKDSDDFGKVKYS-IGLKDRKYFSIDEISGEVRLA----NEIDRETKDFYNVSVIATDGGGLKDYSYIEISILDVNDNYPKLKSGSSMRVN--ENLPVGSVVGYISVIDLDLGDNSKVEWTYDFL-GNSSSMLQI 1912
V+ K+ +P K VVI ++D NDN P F+ + ++ E+ A D D +Y ++ GN F++ + + +++ +S D++ EK+F L++ A D+GG+S T + +N+ D N+ PIF+ + ++ E+ +L ++ATD D G NAQI+Y + SIN + F + +TG I LD E S + + V A D G+P LSD+ +++ VTD+NDN+P + P+ + + D + V + D DV +I L +E S+ I T + D E L+ + D G P + + I ++DVND+ P F + E+ ++ A D D V YS IG D FS+ G R E+D E+ V+ L++ ++IEI + DVNDN P L+ + N ++ P G +G I D D+ D + Y L GN++++L++
Sbjct: 764 VVAKDGGVPPKSASSSVVITVQDVNDNDPAFNPKYYEANVGEDQPPGTPVTTVTATDPD--EDSRLHYEITTGNTRGRFAITSQNGRGLITIAQSLDYKQ--EKRFLLTVAATDSGGRSDTATVHINITDANNFAPIFENAPYSASVFEDAPVGTTVLVVSATDSDVGVNAQITYSLNEESINGLGSPDPFSINPQTGAIVTNAPLDRETTS--GYLLTVTAKDGGNPSLSDTTDVEIGVTDVNDNAPAFK----SPLYQASILEDALVGTSVIQVAASDPDVGLNG-RIKYLLSDRDIEDGSFVIDPTSGTIRTNKGLDRESVAVFHLTAIAVDKGSPPLSSTVEVQIRLEDVNDSPPTFASDKITLYVPENSPVGSVVGEIHAHDPDEGVNAVVHYSIIGGDDSNAFSLVTRPGSERAQLLTMTELDYESTRKRFELVVRAASPPLRNDAHIEILVTDVNDNAPVLRDFQVIFNNFRDHFPSGE-IGRIPAFDADVSD----KLHYRILSGNNANLLRL 1268 HSP 4 Score: 122.094 bits (305), Expect = 1.889e-27 Identity = 126/514 (24.51%), Postives = 223/514 (43.39%), Query Frame = 2
Query: 788 DINDNPPIFQKKIVNVTIQENTTFPDAILKLNATDLDSGNNAQISYKFSSINRPIIRETFQLQSETGKIYLLKTLDYELYSEQNFDINVLAIDHGSPQLSDSCIIKVNVTDINDNSPVIEIVHSQP-IPENEQITDPALKLYVSDYD-----SIDNDVKCQAEKIG----RRLKLEQVEKSSYFIYATEIYDYEKEKNLSLSILCQD---SGKEPRYTKQLLTIFIKDVNDNRPKFLRSFYRKSINEDQ---EKLKPFTKVQALDKDSDDFGKVKYS-IGLKDRKYFSIDEISGEVRLANEIDRETKDFYNVSVIATDGG--GLKDYSYIEISILDVNDNYPKL-KSGSSMRVNENLPVGSVVGYISVIDLDLGDNSKVEWTYDFLGNSSSM-LQIENCTVYTSTV--LDRESIEHLHILITMVDMGYPRLTSSATITVSVIDENDNIPKVIYPKTGSLVEEREMDHIAVNSPKYTTVLSIKSFDPDLGINGDVLYHILPSNGSQYFIINQTSG 2260
++ + P F++ + ++ E A+ + A D + ++ + Y S+ + F++ S TG + +LD EL F V+A D P S + ++VNV D ND+SP E + I E + + L +D D I+ ++ + G + + + +++ S I D E + L + D + E R + + + D NDN P+F Y + EDQ + ++A D D + ++Y+ IG + FSID +SG+V L +D E+ Y + + A DGG + + + ++++D NDN P+ S V EN+PVG + + D D G N+++ TY + L ++ T + T+ LDRE + D G P ++S+++ ++V D NDN P PK ++ + P T V ++ + DPD + + Y I N F I +G
Sbjct: 351 ELRNQSPYFEQALYVASVLEEQPAGAAVTTVRARDPE---DSPVVYSMVSLLDSRSQSLFKVDSRTGVVTTSASLDRELMDVHYF--RVVATDDSFPPRSGTTTLQVNVLDCNDHSPTFEAEQFEASIREGATVGSTVITLRATDQDIGKNAEIEYGIEAVTDGAGLAQDQEMPIFRIDSRSGVISTRSSLDRETSDSYHLLVTAADLASAQSERRTATASVQVKVLDDNDNYPQFSERTYTVQVPEDQWGGTEDNTVAHIRATDADQGNNAAIRYAIIGGNTQSQFSIDSMSGDVSLVKPLDYESVRSYRLVIRAQDGGSPSRSNTTQLLVNVIDANDNAPRFYTSQFQESVLENVPVGYNIIRVQAYDSDEGANAEI--TYSISERDDNFPLAVDPRTGWVQTIKPLDREEQGRFAFQVVAKDGGVPPKSASSSVVITVQDVNDNDP-AFNPKYYEA-------NVGEDQPPGTPVTTVTATDPDE--DSRLHYEITTGNTRGRFAITSQNG 847
BLAST of Protocadherin alpha-2 vs. Ensembl Zebrafish
Match: pcdh11 (protocadherin 11 [Source:ZFIN;Acc:ZDB-GENE-140106-21]) HSP 1 Score: 240.736 bits (613), Expect = 3.421e-65 Identity = 222/700 (31.71%), Postives = 339/700 (48.43%), Query Frame = 2
Query: 254 RRSSFTKFNQYFRISD---------SGEIRITKVFDRDDVNNVCGPLGCCDKPSCEIVLDIIVTVIPKNERIPVKVVIVIEDENDNAPDXXXXXXXXXXXXNDATQLDHNLPKALDKDCPIYGIKNYSLSGNKVEYFSLKIRQFQ-----PFLSVKKSFDFENPSEKQFNLSLNAIDNGG--KSATLQLIVNVIDINDNPPIFQKKIVNVTIQENTTFPDAILKLNATDLDSGNNAQISYKFSSINRPIIRETFQLQSETGKIYLLKTLDYELYSEQNFDINVLAIDHGSPQLSDSCIIKVNVTDINDNSPVIE-----------IVHSQPIPENEQITDPALKLYVSDYDS-IDNDVKCQAEKIGRRLKLEQVEKSSYFIYATEIYDYEKEKNLSLSILCQDSGKEPRYTKQLLTIFIKDVNDNRPKFLRSFYRKSINEDQEKLKPFTKVQALDKDSDDFGKVKYSIGLKDRKYFSIDEISGEVRLANEIDRETKDFYNVSVIATDGGG--LKDYSYIEISILDVNDNYPKLKSGS-SMRVNENLPVGSVVGYISVIDLDLGDNSKVEWTYDFLGNSSSMLQIENCTVYTSTVLDRESIEHLHILITMVDMGYPRLTSSATITVSVIDENDNIPKVIYPKTGSLVEEREMDHIAVNSPKYTTVLSIKSFDPDLGINGDVLYHILPSNGSQYFIINQTSG 2260
+ SS +F ++ D +GEI T +R D +C G ++ C +I V V+P VK+ +IED NDNAP F + ISI EN A + +P A D D I GI++Y L V F L I + P L V++S D E ++ F + + D G KS+T L V V D+NDN P+F+ V V + EN ++ L+ATD D G+NAQI + FS+ P + F + S TG I + + LD E+ + VLA D GS S + +I VNVTDINDN P I+ ++ S+ P N +I AL + V+D DS ++ V C + +L+ V + + DYE + ++ I+ DSGK P T ++ I IKD NDN P F + + SI E+ + K+ A D DS + YS+G F+ID SG + + +DRE ++ Y+ +VIA D G L+ +++ + D NDN P + V ENLP+ VG I+V D D GDN+ V + G + ++ + + + DRE ++ VD G + TS A +T++V+D NDN P + P + D + N+ + V + + D D G+N ++ Y I+ + F I++T+G
Sbjct: 56 KLSSALQFKPVYKTGDVPLVKVEASTGEILTTA--NRIDREKLCS--GVFNEKRC--YYEIEVAVLPDEIFRLVKIRFLIEDINDNAPLFQSTVINISIPENTAINSRYPVPSAFDPDIGINGIQHYELV-KSVSEFGLDIIETPEGDKWPQLIVQQSLDRE--TKDTFVMKIKVEDGGNPPKSSTAILQVTVSDVNDNRPVFKDSEVEVNVPENAPMGTSVTHLHATDADLGSNAQIHFSFSNQISPSTKRHFAIDSTTGLITVKQPLDREVNPVHK--LIVLASD-GSSTPSRATVI-VNVTDINDNVPSIDTRYIMNLVNGTVLLSENAPLNTKI---AL-ITVTDRDSDLNGKVTCYTDH-DVPFRLKPVFNDQFLLETAAPLDYETTREYAIRIVASDSGKPPLNTSAMVLIKIKDENDNVPVFPQPEIQLSIPENNDPGTQLIKISATDADSGSNALIIYSLGPDAPDGFNIDSRSGILSVVKRLDREKQEKYSFTVIARDNGTTPLQSNVTVKLIVQDQNDNSPAFTHPEYNFYVPENLPLYGTVGLITVTDADAGDNAVVTLSI-INGKDNFIIDPKTGVIKPNITFDREQQSSYTFVVKAVDAGLMQTTSYAKVTINVVDVNDNRPVFVIPSSN-----YSYDLVPSNTSPGSVVTRVFAIDNDTGMNAELQYSIIGGSLRGLFTIDKTTG 731 HSP 2 Score: 120.553 bits (301), Expect = 4.034e-27 Identity = 142/524 (27.10%), Postives = 231/524 (44.08%), Query Frame = 2
Query: 788 DINDNPPIFQKKIVNVTIQENTTFPDAILKLNATDLDSGNNAQISYKF----SSINRPIIRETFQLQSETGKIYLLKTLDYELYSEQNFDINVLAIDHGSPQLSDSCIIKVNVTDINDNSPVIEIVHSQP-IPENEQITDPALKLYVSDYDSIDNDVKCQ---AEKIGRRLKLE-QVEKSSYFIYATEIYDYEKEKNLSLSILCQDSGKEPRYTKQLLTIFIKDVNDNRPKFLRSFYRKSIN------EDQEKLKPFTKVQALDKDSDDFGKVK----YSIGLKDRKYFSIDEISGEVRLANEIDRETKDFYNVSVIATDGGG--LKDYSYIEISILDVNDNYPKLKSGS-SMRVNENLPVGSVVGYISVIDLDLGDNSKVEWTYDFLGNSSSMLQIENCTVYTSTV--LDRESIEHLHILITMVDMGYPRLTSSATITVSVIDENDNIPKVIYPKTGSLVEEREMDHIAVNSPKYTTVLSIKSFDPDLGINGDVLYHILPSNGSQYFIINQTSGVLKTTWIYD 2287
DINDN P+FQ ++N++I ENT +A D D G N Y+ S II ET + + ++ + ++LD E ++ F + + D G+P S + I++V V+D+NDN PV + + +PEN + L+ +D D + ++ + + +I K ++ ++ I + D E L +L D P ++ + + + D+NDN P + +N E+ + D+DSD GKV + + + + F+ D+ E A +D ET Y + ++A+D G L + + I I D NDN P + + EN G+ + IS D D G N+ + Y ++ I++ + S V LDRE E + D G L S+ T+ + V D+NDN P +P+ V E N P Y TV I D D G N V I+ NG FII+ +GV+K +D
Sbjct: 131 DINDNAPLFQSTVINISIPENTAINSRYPVPSAFDPDIGINGIQHYELVKSVSEFGLDII-ETPE-GDKWPQLIVQQSLDRE--TKDTFVMKIKVEDGGNPPKSSTAILQVTVSDVNDNRPVFKDSEVEVNVPENAPMGTSVTHLHATDAD-LGSNAQIHFSFSNQISPSTKRHFAIDSTTGLITVKQPLDREVNPVHKLIVLASDGSSTP--SRATVIVNVTDINDNVPSIDTRYIMNLVNGTVLLSENAPLNTKIALITVTDRDSDLNGKVTCYTDHDVPFRLKPVFN-DQFLLET--AAPLDYETTREYAIRIVASDSGKPPLNTSAMVLIKIKDENDNVPVFPQPEIQLSIPENNDPGTQLIKISATDADSGSNALI--IYSLGPDAPDGFNIDSRSGILSVVKRLDREKQEKYSFTVIARDNGTTPLQSNVTVKLIVQDQNDNSPAFTHPEYNFYVPE--------NLPLYGTVGLITVTDADAGDNAVVTLSII--NGKDNFIIDPKTGVIKPNITFD 632
BLAST of Protocadherin alpha-2 vs. Ensembl Zebrafish
Match: pcdh11 (protocadherin 11 [Source:ZFIN;Acc:ZDB-GENE-140106-21]) HSP 1 Score: 241.121 bits (614), Expect = 5.449e-65 Identity = 222/700 (31.71%), Postives = 339/700 (48.43%), Query Frame = 2
Query: 254 RRSSFTKFNQYFRISD---------SGEIRITKVFDRDDVNNVCGPLGCCDKPSCEIVLDIIVTVIPKNERIPVKVVIVIEDENDNAPDXXXXXXXXXXXXNDATQLDHNLPKALDKDCPIYGIKNYSLSGNKVEYFSLKIRQFQ-----PFLSVKKSFDFENPSEKQFNLSLNAIDNGG--KSATLQLIVNVIDINDNPPIFQKKIVNVTIQENTTFPDAILKLNATDLDSGNNAQISYKFSSINRPIIRETFQLQSETGKIYLLKTLDYELYSEQNFDINVLAIDHGSPQLSDSCIIKVNVTDINDNSPVIE-----------IVHSQPIPENEQITDPALKLYVSDYDS-IDNDVKCQAEKIGRRLKLEQVEKSSYFIYATEIYDYEKEKNLSLSILCQDSGKEPRYTKQLLTIFIKDVNDNRPKFLRSFYRKSINEDQEKLKPFTKVQALDKDSDDFGKVKYSIGLKDRKYFSIDEISGEVRLANEIDRETKDFYNVSVIATDGGG--LKDYSYIEISILDVNDNYPKLKSGS-SMRVNENLPVGSVVGYISVIDLDLGDNSKVEWTYDFLGNSSSMLQIENCTVYTSTVLDRESIEHLHILITMVDMGYPRLTSSATITVSVIDENDNIPKVIYPKTGSLVEEREMDHIAVNSPKYTTVLSIKSFDPDLGINGDVLYHILPSNGSQYFIINQTSG 2260
+ SS +F ++ D +GEI T +R D +C G ++ C +I V V+P VK+ +IED NDNAP F + ISI EN A + +P A D D I GI++Y L V F L I + P L V++S D E ++ F + + D G KS+T L V V D+NDN P+F+ V V + EN ++ L+ATD D G+NAQI + FS+ P + F + S TG I + + LD E+ + VLA D GS S + +I VNVTDINDN P I+ ++ S+ P N +I AL + V+D DS ++ V C + +L+ V + + DYE + ++ I+ DSGK P T ++ I IKD NDN P F + + SI E+ + K+ A D DS + YS+G F+ID SG + + +DRE ++ Y+ +VIA D G L+ +++ + D NDN P + V ENLP+ VG I+V D D GDN+ V + G + ++ + + + DRE ++ VD G + TS A +T++V+D NDN P + P + D + N+ + V + + D D G+N ++ Y I+ + F I++T+G
Sbjct: 56 KLSSALQFKPVYKTGDVPLVKVEASTGEILTTA--NRIDREKLCS--GVFNEKRC--YYEIEVAVLPDEIFRLVKIRFLIEDINDNAPLFQSTVINISIPENTAINSRYPVPSAFDPDIGINGIQHYELV-KSVSEFGLDIIETPEGDKWPQLIVQQSLDRE--TKDTFVMKIKVEDGGNPPKSSTAILQVTVSDVNDNRPVFKDSEVEVNVPENAPMGTSVTHLHATDADLGSNAQIHFSFSNQISPSTKRHFAIDSTTGLITVKQPLDREVNPVHK--LIVLASD-GSSTPSRATVI-VNVTDINDNVPSIDTRYIMNLVNGTVLLSENAPLNTKI---AL-ITVTDRDSDLNGKVTCYTDH-DVPFRLKPVFNDQFLLETAAPLDYETTREYAIRIVASDSGKPPLNTSAMVLIKIKDENDNVPVFPQPEIQLSIPENNDPGTQLIKISATDADSGSNALIIYSLGPDAPDGFNIDSRSGILSVVKRLDREKQEKYSFTVIARDNGTTPLQSNVTVKLIVQDQNDNSPAFTHPEYNFYVPENLPLYGTVGLITVTDADAGDNAVVTLSI-INGKDNFIIDPKTGVIKPNITFDREQQSSYTFVVKAVDAGLMQTTSYAKVTINVVDVNDNRPVFVIPSSN-----YSYDLVPSNTSPGSVVTRVFAIDNDTGMNAELQYSIIGGSLRGLFTIDKTTG 731 HSP 2 Score: 121.324 bits (303), Expect = 2.370e-27 Identity = 142/524 (27.10%), Postives = 231/524 (44.08%), Query Frame = 2
Query: 788 DINDNPPIFQKKIVNVTIQENTTFPDAILKLNATDLDSGNNAQISYKF----SSINRPIIRETFQLQSETGKIYLLKTLDYELYSEQNFDINVLAIDHGSPQLSDSCIIKVNVTDINDNSPVIEIVHSQP-IPENEQITDPALKLYVSDYDSIDNDVKCQ---AEKIGRRLKLE-QVEKSSYFIYATEIYDYEKEKNLSLSILCQDSGKEPRYTKQLLTIFIKDVNDNRPKFLRSFYRKSIN------EDQEKLKPFTKVQALDKDSDDFGKVK----YSIGLKDRKYFSIDEISGEVRLANEIDRETKDFYNVSVIATDGGG--LKDYSYIEISILDVNDNYPKLKSGS-SMRVNENLPVGSVVGYISVIDLDLGDNSKVEWTYDFLGNSSSMLQIENCTVYTSTV--LDRESIEHLHILITMVDMGYPRLTSSATITVSVIDENDNIPKVIYPKTGSLVEEREMDHIAVNSPKYTTVLSIKSFDPDLGINGDVLYHILPSNGSQYFIINQTSGVLKTTWIYD 2287
DINDN P+FQ ++N++I ENT +A D D G N Y+ S II ET + + ++ + ++LD E ++ F + + D G+P S + I++V V+D+NDN PV + + +PEN + L+ +D D + ++ + + +I K ++ ++ I + D E L +L D P ++ + + + D+NDN P + +N E+ + D+DSD GKV + + + + F+ D+ E A +D ET Y + ++A+D G L + + I I D NDN P + + EN G+ + IS D D G N+ + Y ++ I++ + S V LDRE E + D G L S+ T+ + V D+NDN P +P+ V E N P Y TV I D D G N V I+ NG FII+ +GV+K +D
Sbjct: 131 DINDNAPLFQSTVINISIPENTAINSRYPVPSAFDPDIGINGIQHYELVKSVSEFGLDII-ETPE-GDKWPQLIVQQSLDRE--TKDTFVMKIKVEDGGNPPKSSTAILQVTVSDVNDNRPVFKDSEVEVNVPENAPMGTSVTHLHATDAD-LGSNAQIHFSFSNQISPSTKRHFAIDSTTGLITVKQPLDREVNPVHKLIVLASDGSSTP--SRATVIVNVTDINDNVPSIDTRYIMNLVNGTVLLSENAPLNTKIALITVTDRDSDLNGKVTCYTDHDVPFRLKPVFN-DQFLLET--AAPLDYETTREYAIRIVASDSGKPPLNTSAMVLIKIKDENDNVPVFPQPEIQLSIPENNDPGTQLIKISATDADSGSNALI--IYSLGPDAPDGFNIDSRSGILSVVKRLDREKQEKYSFTVIARDNGTTPLQSNVTVKLIVQDQNDNSPAFTHPEYNFYVPE--------NLPLYGTVGLITVTDADAGDNAVVTLSII--NGKDNFIIDPKTGVIKPNITFD 632
BLAST of Protocadherin alpha-2 vs. Ensembl Zebrafish
Match: pcdh9 (protocadherin 9 [Source:ZFIN;Acc:ZDB-GENE-091015-1]) HSP 1 Score: 231.876 bits (590), Expect = 2.857e-62 Identity = 200/672 (29.76%), Postives = 322/672 (47.92%), Query Frame = 2
Query: 293 ISDSGEIRITKVFDRDDVNNVCGPLGCCDKPSCEIVLDIIVTVIPKNERIPVKVVIVIEDENDNAPDXXXXXXXXXXXXNDATQLDHNLPKALDKDCPIYGIKNYSLSGNKVEYFSLKIRQFQ-----PFLSVKKSFDFENPSEKQFNLSLNAIDNGGKSATLQLIVNVIDINDNPPIFQKKIVNVTIQENTTFPDAILKLNATDLDSGNNAQISYKFSSINRPIIRETFQLQSETGKIYLLKTLDYELYSEQNFDINVLAIDHGSPQLSDSCIIKVNVTDINDNSPVIEIVH-------SQPIPENEQITDPALKLYVSDYDS-IDNDVKCQAEKIGRRLKLEQVEKSSYFIYATEIYDYEKEKNLSLSILCQDSGKEPRYTKQLLTIFIKDVNDNRPKFLRSFYRKSINEDQEKLKPFTKVQALDKDSDDFGKVKYSIGLKDRKYFSIDEISGEVRLANEIDRETKDFYNVSVIATDGG--GLKDYSYIEISILDVNDNYPKLKSGS-SMRVNENLPVGSVVGYISVIDLDLGDNSKVEWTYDFLGNSSSMLQIENCTVYTSTVLDRESIEHLHILITMVDMGYPRLTSSATITVSVIDENDNIPKVIYPKTGSLVEEREMDHIAVNSPKYTTVLSIKSFDPDLGINGDVLYHILPSNGSQYFIINQTSG 2260
+S++GEI T +R D +C P + C +I V ++P + +K+ I+++D NDNAP F ISI EN +P A D D + Y L N F L I + P L V+++ D E + + N KS+T L V V D+NDN P+F++ + V I EN+ ++++L ATD D G NA+I Y F + P R F L + TG I + + LD E + + VLA D S I +NVTD+NDN+P I++ + + + E + I + VSD D+ ++ V C EK L+ V + Y + + + DYE K I+ DSGK L+ + ++D NDN P F + ++ E+ + T + A D+DS ++ Y +G + +F +D +G + + DRE ++ + +V A D G L+ + + ++ILD NDN PK V+ENLP S VG I+V D D G+N+ V + N + +L ++ + ++ DRE + VD G P +S+A +T++VID NDN P VIYP + + + +++ + V + + D D G+N ++ Y I+ N F I+ +G
Sbjct: 79 MSNTGEIFTTS--NRIDREKLC-PGPSFEDSECS--FEIEVVILPNDYFRLIKIKIIVKDTNDNAPMFPSPVINISIPENTLINSRFAIPSATDPDTGPNSVHKYELL-NGQSAFGLDIVETPEGEKWPQLIVQQNLDREQKDTYVMKVKVEDGGNPQKSSTAILQVTVTDVNDNRPVFKESQIEVHIPENSPVGTSVVQLQATDADVGANAEIKYMFGAQVSPATRRLFALNTTTGLITVQRPLDREETAIHK--LTVLASDGSSSPA--RATITINVTDVNDNAPNIDLRYIISPTNGTVMLSEKDPINTKIALITVSDKDTDVNGKVICFIEK-DVPFHLKAVYDNQYLLETSALLDYEGTKEYIFKIVASDSGKPSLNQTALVRVRLEDENDNPPIFTQPVIELAVMENNLRDMFLTTISATDEDSGRNAEIVYQLG-PNASFFDLDRKTGVLTASRVFDREEQERFLFTVTARDNGTRALQSQAAVIVTILDENDNSPKFTHNHFQFFVSENLPKYSTVGVITVTDADAGENAVVRLSI-LNDNENFILDPDSGVIKSNVSFDREQQSSYTFDVRAVDNGSPPCSSAAKVTINVIDVNDNTPIVIYPPSNT-----SFKLVPLSAIPGSVVAEVFAVDGDTGMNAELKYTIVSGNVRSLFRIDPVTG 732 HSP 2 Score: 140.198 bits (352), Expect = 4.028e-33 Identity = 155/542 (28.60%), Postives = 241/542 (44.46%), Query Frame = 2
Query: 764 LQLIVNVIDINDNPPIFQKKIVNVTIQENTTFPDAILKLNATDLDSGNNAQISYKFSSINRPIIRETFQL---QSETGKIYLLKTLDYELYSEQ--NFDINVLAIDHGSPQLSDSCIIKVNVTDINDNSPVIEI----VHSQPIPENEQITDPALKLYVSDYD-SIDNDVK----CQAEKIGRRLKLEQVEKSSYFIYATEIYDYEKEKNLSLSILCQDSGKEPRYTKQLLTIFIKDVNDNRPKFLRSFYRKSINED---QEKLKPFTKVQAL---DKDSDDFGKVKYSI---------GLKDRKYFSIDEISGEVRLANEIDRETKDFYNVSVIATDGG--GLKDYSYIEISILDVNDNYPKLKSGS-SMRVNENLPVGSVVGYISVIDLDLGDNSKVEWTYDFLGNSSSMLQIENCT--VYTSTVLDRESIEHLHILITMVDMGYPRLTSSATITVSVIDENDNIPKVIYPKTGSLVEEREMDHIAVNSPKYTTVLSIKSFDPDLGINGDVLYHILPSNGSQYFIINQTSGVLKTTWIYD 2287
+++ + V D NDN P+F ++N++I ENT +ATD D+G N+ +K+ +N + F L ++ G+ + + L EQ + + V D G+PQ S + I++V VTD+NDN PV + VH IPEN + ++L +D D + ++K Q RRL + ++ I D E+ L++L D P + +TI + DVNDN P + N EK TK+ + DKD+D GKV I + D +Y + + +D E Y ++A+D G L + + + + D NDN P + V EN + IS D D G N+++ + LG ++S ++ T + S V DRE E +T D G L S A + V+++DENDN PK + V E N PKY+TV I D D G N V IL N ++ FI++ SGV+K+ +D
Sbjct: 125 IKIKIIVKDTNDNAPMFPSPVINISIPENTLINSRFAIPSATDPDTGPNS--VHKYELLNG---QSAFGLDIVETPEGEKWPQLIVQQNLDREQKDTYVMKVKVEDGGNPQKSSTAILQVTVTDVNDNRPVFKESQIEVH---IPENSPVGTSVVQLQATDADVGANAEIKYMFGAQVSPATRRLF--ALNTTTGLITVQRPLDREETAIHKLTVLASDGSSSP--ARATITINVTDVNDNAPNIDLRYIISPTNGTVMLSEKDPINTKIALITVSDKDTDVNGKVICFIEKDVPFHLKAVYDNQYL--------LETSALLDYEGTKEYIFKIVASDSGKPSLNQTALVRVRLEDENDNPPIFTQPVIELAVMENNLRDMFLTTISATDEDSGRNAEIVYQ---LGPNASFFDLDRKTGVLTASRVFDREEQERFLFTVTARDNGTRALQSQAAVIVTILDENDNSPKFTHNHFQFFVSE--------NLPKYSTVGVITVTDADAGENAVVRLSIL--NDNENFILDPDSGVIKSNVSFD 633 HSP 3 Score: 129.028 bits (323), Expect = 9.076e-30 Identity = 120/472 (25.42%), Postives = 227/472 (48.09%), Query Frame = 2
Query: 665 FLSVKKSFDFENPSEKQFNLSLNAIDNGGKSATLQLIVNVIDINDNPPIFQKKIV------NVTIQENTTFPDAILKLNATDLDSGNNAQISYKFSSINRPIIRETFQLQSETGKIYLLKT---LDYELYSEQNFDINVLAIDHGSPQLSDSCIIKVNVTDINDNSPVIEIVHSQPIPENEQITDPALKLYVSDYDSIDNDVKCQAE---KIGRRLKLEQVEKSSYFIYATEIYDYEKEKNLSLSILCQDSGKEPRYTKQLLTIFIKDVNDNRPKFLRSFYRKSINEDQEKLKPFTKVQALDKDSDDFGKVKYSIGLKDRKYFSIDEISGEVRLANEIDRETKDFYNVSVIATDGGG--LKDYSYIEISILDVNDNYPKL---KSGSSMRVNENLPV----GSVVGYISVIDLDLGDNSKVEWTYDFLGNSSSMLQIENCTVYTSTVLDRESIEH--LH-ILITMVDMGYPR 2008
++V++ D E + + L++ A D A + +NV D+NDN P + + V + E I + +D D+ N ++ F + P F L++ YLL+T LDYE E F I +A D G P L+ + +++V + D NDN P+ +QP+ E + + ++++ + D D AE ++G +++ + + A+ ++D E+++ ++ +D+G ++ + + I D NDN PKF + ++ ++E+ K + D D+ + V+ SI L D + F +D SG ++ DRE + Y V A D G + + I+++DVNDN P + S +S ++ +P+ GSVV + +D D G N+++++T GN S+ +I+ T T+ ++ +I LH +++ + D+GYP+
Sbjct: 310 LITVQRPLDREETAIHK--LTVLASDGSSSPARATITINVTDVNDNAPNIDLRYIISPTNGTVMLSEKDPINTKIALITVSDKDTDVNGKV-ICFIEKDVP-----FHLKAVYDNQYLLETSALLDYEGTKEYIFKI--VASDSGKPSLNQTALVRVRLEDENDNPPIF----TQPVIELAVMENNLRDMFLTTISATDEDSGRNAEIVYQLGPNASFFDLDRKTGVLTASRVFDREEQERFLFTVTARDNGTRALQSQAAVIVTILDENDNSPKFTHNHFQFFVSENLPKYSTVGVITVTDADAGENAVVRLSI-LNDNENFILDPDSGVIKSNVSFDREQQSSYTFDVRAVDNGSPPCSSAAKVTINVIDVNDNTPIVIYPPSNTSFKL---VPLSAIPGSVVAEVFAVDGDTGMNAELKYTI-VSGNVRSLFRIDPVT-GNITLEEKPTIADIGLHRLVVNISDLGYPK 761
BLAST of Protocadherin alpha-2 vs. Ensembl Zebrafish
Match: CR847522.1 (pep chromosome:GRCz11:CHR_ALT_CTG6_1_1:4874141:4879379:1 gene:ENSDARG00000111493.1 transcript:ENSDART00000185190.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CR847522.1) HSP 1 Score: 231.876 bits (590), Expect = 4.315e-62 Identity = 200/672 (29.76%), Postives = 322/672 (47.92%), Query Frame = 2
Query: 293 ISDSGEIRITKVFDRDDVNNVCGPLGCCDKPSCEIVLDIIVTVIPKNERIPVKVVIVIEDENDNAPDXXXXXXXXXXXXNDATQLDHNLPKALDKDCPIYGIKNYSLSGNKVEYFSLKIRQF-----QPFLSVKKSFDFENPSEKQFNLSLNAIDNGGKSATLQLIVNVIDINDNPPIFQKKIVNVTIQENTTFPDAILKLNATDLDSGNNAQISYKFSSINRPIIRETFQLQSETGKIYLLKTLDYELYSEQNFDINVLAIDHGSPQLSDSCIIKVNVTDINDNSPVIEIVH-------SQPIPENEQITDPALKLYVSDYDS-IDNDVKCQAEKIGRRLKLEQVEKSSYFIYATEIYDYEKEKNLSLSILCQDSGKEPRYTKQLLTIFIKDVNDNRPKFLRSFYRKSINEDQEKLKPFTKVQALDKDSDDFGKVKYSIGLKDRKYFSIDEISGEVRLANEIDRETKDFYNVSVIATDGG--GLKDYSYIEISILDVNDNYPKLKSGS-SMRVNENLPVGSVVGYISVIDLDLGDNSKVEWTYDFLGNSSSMLQIENCTVYTSTVLDRESIEHLHILITMVDMGYPRLTSSATITVSVIDENDNIPKVIYPKTGSLVEEREMDHIAVNSPKYTTVLSIKSFDPDLGINGDVLYHILPSNGSQYFIINQTSG 2260
+S++GEI T +R D +C P + C +I V ++P + +K+ I+++D NDNAP F ISI EN +P A D D + Y L N F L I + P L V+++ D E + + N KS+T L V V D+NDN P+F++ + V I EN+ ++++L ATD D G NA+I Y F + P R F L + TG I + + LD E + + VLA D S I +NVTD+NDN+P I++ + + + E + I + VSD D+ ++ V C EK L+ V + Y + + + DYE K I+ DSGK L+ + ++D NDN P F + ++ E+ + T + A D+DS ++ Y +G + +F +D +G + + DRE ++ + +V A D G L+ + + ++ILD NDN PK V+ENLP S VG I+V D D G+N+ V + N + +L ++ + ++ DRE + VD G P +S+A +T++VID NDN P VIYP + + + +++ + V + + D D G+N ++ Y I+ N F I+ +G
Sbjct: 79 MSNTGEIFTTS--NRIDREKLC-PGPSFEDSECS--FEIEVVILPNDYFRLIKIKIIVKDTNDNAPMFPSPVINISIPENTLINSRFAIPSATDPDTGPNSVHKYELL-NGQSAFGLDIVETPEGEKWPQLIVQQNLDREQKDTYVMKVKVEDGGNPQKSSTAILQVTVTDVNDNRPVFKESQIEVHIPENSPVGTSVVQLQATDADVGANAEIKYMFGAQVSPATRRLFALNTTTGLITVQRPLDREETAIHK--LTVLASDGSSSPA--RATITINVTDVNDNAPNIDLRYIISPTNGTVMLSEKDPINTKIALITVSDKDTDVNGKVICFIEK-DVPFHLKAVYDNQYLLETSALLDYEGTKEYIFKIVASDSGKPSLNQTALVRVRLEDENDNPPIFTQPVIELAVMENNLRDMFLTTISATDEDSGRNAEIVYQLG-PNASFFDLDRKTGVLTASRVFDREEQERFLFTVTARDNGTRALQSQAAVIVTILDENDNSPKFTHNHFQFFVSENLPKYSTVGVITVTDADAGENAVVRLSI-LNDNENFILDPDSGVIKSNVSFDREQQSSYTFDVRAVDNGSPPCSSAAKVTINVIDVNDNTPIVIYPPSNT-----SFKLVPLSAIPGSVVAEVFAVDGDTGMNAELKYTIVSGNVRSLFRIDPVTG 732 HSP 2 Score: 139.813 bits (351), Expect = 5.058e-33 Identity = 156/542 (28.78%), Postives = 241/542 (44.46%), Query Frame = 2
Query: 764 LQLIVNVIDINDNPPIFQKKIVNVTIQENTTFPDAILKLNATDLDSGNNAQISYKFSSINRPIIRETFQL---QSETGKIYLLKTLDYELYSEQ--NFDINVLAIDHGSPQLSDSCIIKVNVTDINDNSPVIEI----VHSQPIPENEQITDPALKLYVSDYDSIDN-DVK----CQAEKIGRRLKLEQVEKSSYFIYATEIYDYEKEKNLSLSILCQDSGKEPRYTKQLLTIFIKDVNDNRPKFLRSFYRKSINED---QEKLKPFTKVQAL---DKDSDDFGKVKYSI---------GLKDRKYFSIDEISGEVRLANEIDRETKDFYNVSVIATDGG--GLKDYSYIEISILDVNDNYPKLKSGS-SMRVNENLPVGSVVGYISVIDLDLGDNSKVEWTYDFLGNSSSMLQIENCT--VYTSTVLDRESIEHLHILITMVDMGYPRLTSSATITVSVIDENDNIPKVIYPKTGSLVEEREMDHIAVNSPKYTTVLSIKSFDPDLGINGDVLYHILPSNGSQYFIINQTSGVLKTTWIYD 2287
+++ + V D NDN P+F ++N++I ENT +ATD D+G N+ +K+ +N + F L ++ G+ + + L EQ + + V D G+PQ S + I++V VTD+NDN PV + VH IPEN + ++L +D D N ++K Q RRL + ++ I D E+ L++L D P + +TI + DVNDN P + N EK TK+ + DKD+D GKV I + D +Y + + +D E Y ++A+D G L + + + + D NDN P + V EN + IS D D G N+++ + LG ++S ++ T + S V DRE E +T D G L S A + V+++DENDN PK + V E N PKY+TV I D D G N V IL N ++ FI++ SGV+K+ +D
Sbjct: 125 IKIKIIVKDTNDNAPMFPSPVINISIPENTLINSRFAIPSATDPDTGPNS--VHKYELLNG---QSAFGLDIVETPEGEKWPQLIVQQNLDREQKDTYVMKVKVEDGGNPQKSSTAILQVTVTDVNDNRPVFKESQIEVH---IPENSPVGTSVVQLQATDADVGANAEIKYMFGAQVSPATRRLF--ALNTTTGLITVQRPLDREETAIHKLTVLASDGSSSP--ARATITINVTDVNDNAPNIDLRYIISPTNGTVMLSEKDPINTKIALITVSDKDTDVNGKVICFIEKDVPFHLKAVYDNQYL--------LETSALLDYEGTKEYIFKIVASDSGKPSLNQTALVRVRLEDENDNPPIFTQPVIELAVMENNLRDMFLTTISATDEDSGRNAEIVYQ---LGPNASFFDLDRKTGVLTASRVFDREEQERFLFTVTARDNGTRALQSQAAVIVTILDENDNSPKFTHNHFQFFVSE--------NLPKYSTVGVITVTDADAGENAVVRLSIL--NDNENFILDPDSGVIKSNVSFD 633 HSP 3 Score: 129.413 bits (324), Expect = 9.534e-30 Identity = 119/469 (25.37%), Postives = 224/469 (47.76%), Query Frame = 2
Query: 665 FLSVKKSFDFENPSEKQFNLSLNAIDNGGKSATLQLIVNVIDINDNPPIFQKKIV------NVTIQENTTFPDAILKLNATDLDSGNNAQISYKFSSINRPIIRETFQLQSETGKIYLLKT---LDYELYSEQNFDINVLAIDHGSPQLSDSCIIKVNVTDINDNSPVIEIVHSQPIPENEQITDPALKLYVSDYDSIDNDVKCQAE---KIGRRLKLEQVEKSSYFIYATEIYDYEKEKNLSLSILCQDSGKEPRYTKQLLTIFIKDVNDNRPKFLRSFYRKSINEDQEKLKPFTKVQALDKDSDDFGKVKYSIGLKDRKYFSIDEISGEVRLANEIDRETKDFYNVSVIATDGGG--LKDYSYIEISILDVNDNYPKLKSGSSMRVNENLPV----GSVVGYISVIDLDLGDNSKVEWTYDFLGNSSSMLQIENCTVYTSTVLDRESIE--HLH-ILITMVDMGYPR 2008
++V++ D E + + L++ A D A + +NV D+NDN P + + V + E I + +D D+ N ++ F + P F L++ YLL+T LDYE E F I +A D G P L+ + +++V + D NDN P+ +QP+ E + + ++++ + D D AE ++G +++ + + A+ ++D E+++ ++ +D+G ++ + + I D NDN PKF + ++ ++E+ K + D D+ + V+ SI L D + F +D SG ++ DRE + Y V A D G + + I+++DVNDN P + S + +P+ GSVV + +D D G N+++++T GN S+ +I+ T T+ ++ +I LH +++ + D+GYP+
Sbjct: 310 LITVQRPLDREETAIHK--LTVLASDGSSSPARATITINVTDVNDNAPNIDLRYIISPTNGTVMLSEKDPINTKIALITVSDKDTDVNGKV-ICFIEKDVP-----FHLKAVYDNQYLLETSALLDYEGTKEYIFKI--VASDSGKPSLNQTALVRVRLEDENDNPPIF----TQPVIELAVMENNLRDMFLTTISATDEDSGRNAEIVYQLGPNASFFDLDRKTGVLTASRVFDREEQERFLFTVTARDNGTRALQSQAAVIVTILDENDNSPKFTHNHFQFFVSENLPKYSTVGVITVTDADAGENAVVRLSI-LNDNENFILDPDSGVIKSNVSFDREQQSSYTFDVRAVDNGSPPCSSAAKVTINVIDVNDNTPIVIYPPSNTSFKLVPLSAIPGSVVAEVFAVDGDTGMNAELKYTI-VSGNVRSLFRIDPVT-GNITLEEKPTIADIGLHRLVVNISDLGYPK 761
BLAST of Protocadherin alpha-2 vs. Ensembl Zebrafish
Match: pcdh9 (protocadherin 9 [Source:ZFIN;Acc:ZDB-GENE-091015-1]) HSP 1 Score: 231.491 bits (589), Expect = 5.139e-62 Identity = 200/672 (29.76%), Postives = 322/672 (47.92%), Query Frame = 2
Query: 293 ISDSGEIRITKVFDRDDVNNVCGPLGCCDKPSCEIVLDIIVTVIPKNERIPVKVVIVIEDENDNAPDXXXXXXXXXXXXNDATQLDHNLPKALDKDCPIYGIKNYSLSGNKVEYFSLKIRQF-----QPFLSVKKSFDFENPSEKQFNLSLNAIDNGGKSATLQLIVNVIDINDNPPIFQKKIVNVTIQENTTFPDAILKLNATDLDSGNNAQISYKFSSINRPIIRETFQLQSETGKIYLLKTLDYELYSEQNFDINVLAIDHGSPQLSDSCIIKVNVTDINDNSPVIEIVH-------SQPIPENEQITDPALKLYVSDYDS-IDNDVKCQAEKIGRRLKLEQVEKSSYFIYATEIYDYEKEKNLSLSILCQDSGKEPRYTKQLLTIFIKDVNDNRPKFLRSFYRKSINEDQEKLKPFTKVQALDKDSDDFGKVKYSIGLKDRKYFSIDEISGEVRLANEIDRETKDFYNVSVIATDGG--GLKDYSYIEISILDVNDNYPKLKSGS-SMRVNENLPVGSVVGYISVIDLDLGDNSKVEWTYDFLGNSSSMLQIENCTVYTSTVLDRESIEHLHILITMVDMGYPRLTSSATITVSVIDENDNIPKVIYPKTGSLVEEREMDHIAVNSPKYTTVLSIKSFDPDLGINGDVLYHILPSNGSQYFIINQTSG 2260
+S++GEI T +R D +C P + C +I V ++P + +K+ I+++D NDNAP F ISI EN +P A D D + Y L N F L I + P L V+++ D E + + N KS+T L V V D+NDN P+F++ + V I EN+ ++++L ATD D G NA+I Y F + P R F L + TG I + + LD E + + VLA D S I +NVTD+NDN+P I++ + + + E + I + VSD D+ ++ V C EK L+ V + Y + + + DYE K I+ DSGK L+ + ++D NDN P F + ++ E+ + T + A D+DS ++ Y +G + +F +D +G + + DRE ++ + +V A D G L+ + + ++ILD NDN PK V+ENLP S VG I+V D D G+N+ V + N + +L ++ + ++ DRE + VD G P +S+A +T++VID NDN P VIYP + + + +++ + V + + D D G+N ++ Y I+ N F I+ +G
Sbjct: 79 MSNTGEIFTTS--NRIDREKLC-PGPSFEDSECS--FEIEVVILPNDYFRLIKIKIIVKDTNDNAPMFPSPVINISIPENTLINSRFAIPSATDPDTGPNSVHKYELL-NGQSAFGLDIVETPEGEKWPQLIVQQNLDREQKDTYVMKVKVEDGGNPQKSSTAILQVTVTDVNDNRPVFKESQIEVHIPENSPVGTSVVQLQATDADVGANAEIKYMFGAQVSPATRRLFALNTTTGLITVQRPLDREETAIHK--LTVLASDGSSSPA--RATITINVTDVNDNAPNIDLRYIISPTNGTVMLSEKDPINTKIALITVSDKDTDVNGKVICFIEK-DVPFHLKAVYDNQYLLETSALLDYEGTKEYIFKIVASDSGKPSLNQTALVRVRLEDENDNPPIFTQPVIELAVMENNLRDMFLTTISATDEDSGRNAEIVYQLG-PNASFFDLDRKTGVLTASRVFDREEQERFLFTVTARDNGTRALQSQAAVIVTILDENDNSPKFTHNHFQFFVSENLPKYSTVGVITVTDADAGENAVVRLSI-LNDNENFILDPDSGVIKSNVSFDREQQSSYTFDVRAVDNGSPPCSSAAKVTINVIDVNDNTPIVIYPPSNT-----SFKLVPLSAIPGSVVAEVFAVDGDTGMNAELKYTIVSGNVRSLFRIDPVTG 732 HSP 2 Score: 139.813 bits (351), Expect = 5.528e-33 Identity = 155/542 (28.60%), Postives = 241/542 (44.46%), Query Frame = 2
Query: 764 LQLIVNVIDINDNPPIFQKKIVNVTIQENTTFPDAILKLNATDLDSGNNAQISYKFSSINRPIIRETFQL---QSETGKIYLLKTLDYELYSEQ--NFDINVLAIDHGSPQLSDSCIIKVNVTDINDNSPVIEI----VHSQPIPENEQITDPALKLYVSDYD-SIDNDVK----CQAEKIGRRLKLEQVEKSSYFIYATEIYDYEKEKNLSLSILCQDSGKEPRYTKQLLTIFIKDVNDNRPKFLRSFYRKSINED---QEKLKPFTKVQAL---DKDSDDFGKVKYSI---------GLKDRKYFSIDEISGEVRLANEIDRETKDFYNVSVIATDGG--GLKDYSYIEISILDVNDNYPKLKSGS-SMRVNENLPVGSVVGYISVIDLDLGDNSKVEWTYDFLGNSSSMLQIENCT--VYTSTVLDRESIEHLHILITMVDMGYPRLTSSATITVSVIDENDNIPKVIYPKTGSLVEEREMDHIAVNSPKYTTVLSIKSFDPDLGINGDVLYHILPSNGSQYFIINQTSGVLKTTWIYD 2287
+++ + V D NDN P+F ++N++I ENT +ATD D+G N+ +K+ +N + F L ++ G+ + + L EQ + + V D G+PQ S + I++V VTD+NDN PV + VH IPEN + ++L +D D + ++K Q RRL + ++ I D E+ L++L D P + +TI + DVNDN P + N EK TK+ + DKD+D GKV I + D +Y + + +D E Y ++A+D G L + + + + D NDN P + V EN + IS D D G N+++ + LG ++S ++ T + S V DRE E +T D G L S A + V+++DENDN PK + V E N PKY+TV I D D G N V IL N ++ FI++ SGV+K+ +D
Sbjct: 125 IKIKIIVKDTNDNAPMFPSPVINISIPENTLINSRFAIPSATDPDTGPNS--VHKYELLNG---QSAFGLDIVETPEGEKWPQLIVQQNLDREQKDTYVMKVKVEDGGNPQKSSTAILQVTVTDVNDNRPVFKESQIEVH---IPENSPVGTSVVQLQATDADVGANAEIKYMFGAQVSPATRRLF--ALNTTTGLITVQRPLDREETAIHKLTVLASDGSSSP--ARATITINVTDVNDNAPNIDLRYIISPTNGTVMLSEKDPINTKIALITVSDKDTDVNGKVICFIEKDVPFHLKAVYDNQYL--------LETSALLDYEGTKEYIFKIVASDSGKPSLNQTALVRVRLEDENDNPPIFTQPVIELAVMENNLRDMFLTTISATDEDSGRNAEIVYQ---LGPNASFFDLDRKTGVLTASRVFDREEQERFLFTVTARDNGTRALQSQAAVIVTILDENDNSPKFTHNHFQFFVSE--------NLPKYSTVGVITVTDADAGENAVVRLSIL--NDNENFILDPDSGVIKSNVSFD 633 HSP 3 Score: 129.028 bits (323), Expect = 1.141e-29 Identity = 120/472 (25.42%), Postives = 227/472 (48.09%), Query Frame = 2
Query: 665 FLSVKKSFDFENPSEKQFNLSLNAIDNGGKSATLQLIVNVIDINDNPPIFQKKIV------NVTIQENTTFPDAILKLNATDLDSGNNAQISYKFSSINRPIIRETFQLQSETGKIYLLKT---LDYELYSEQNFDINVLAIDHGSPQLSDSCIIKVNVTDINDNSPVIEIVHSQPIPENEQITDPALKLYVSDYDSIDNDVKCQAE---KIGRRLKLEQVEKSSYFIYATEIYDYEKEKNLSLSILCQDSGKEPRYTKQLLTIFIKDVNDNRPKFLRSFYRKSINEDQEKLKPFTKVQALDKDSDDFGKVKYSIGLKDRKYFSIDEISGEVRLANEIDRETKDFYNVSVIATDGGG--LKDYSYIEISILDVNDNYPKL---KSGSSMRVNENLPV----GSVVGYISVIDLDLGDNSKVEWTYDFLGNSSSMLQIENCTVYTSTVLDRESIEH--LH-ILITMVDMGYPR 2008
++V++ D E + + L++ A D A + +NV D+NDN P + + V + E I + +D D+ N ++ F + P F L++ YLL+T LDYE E F I +A D G P L+ + +++V + D NDN P+ +QP+ E + + ++++ + D D AE ++G +++ + + A+ ++D E+++ ++ +D+G ++ + + I D NDN PKF + ++ ++E+ K + D D+ + V+ SI L D + F +D SG ++ DRE + Y V A D G + + I+++DVNDN P + S +S ++ +P+ GSVV + +D D G N+++++T GN S+ +I+ T T+ ++ +I LH +++ + D+GYP+
Sbjct: 310 LITVQRPLDREETAIHK--LTVLASDGSSSPARATITINVTDVNDNAPNIDLRYIISPTNGTVMLSEKDPINTKIALITVSDKDTDVNGKV-ICFIEKDVP-----FHLKAVYDNQYLLETSALLDYEGTKEYIFKI--VASDSGKPSLNQTALVRVRLEDENDNPPIF----TQPVIELAVMENNLRDMFLTTISATDEDSGRNAEIVYQLGPNASFFDLDRKTGVLTASRVFDREEQERFLFTVTARDNGTRALQSQAAVIVTILDENDNSPKFTHNHFQFFVSENLPKYSTVGVITVTDADAGENAVVRLSI-LNDNENFILDPDSGVIKSNVSFDREQQSSYTFDVRAVDNGSPPCSSAAKVTINVIDVNDNTPIVIYPPSNTSFKL---VPLSAIPGSVVAEVFAVDGDTGMNAELKYTI-VSGNVRSLFRIDPVT-GNITLEEKPTIADIGLHRLVVNISDLGYPK 761
BLAST of Protocadherin alpha-2 vs. Ensembl Xenopus
Match: ENSXETT00000047804.1 (protocadherin 11 X-linked [Source:NCBI gene;Acc:100493938]) HSP 1 Score: 226.868 bits (577), Expect = 1.973e-60 Identity = 201/673 (29.87%), Postives = 319/673 (47.40%), Query Frame = 2
Query: 299 DSGEIRITKVFDRDDVNNVCGPLGCCDKPSCEIVLDIIVTVIPKNERIPVKVVIVIEDENDNAPDXXXXXXXXXXXXNDATQLDHNLPKALDKDCPIYGIKNYSL-SGNKVEYFSLKIRQFQ-----PFLSVKKSFDFENPSEKQFNLSLNAIDNGGKSATLQLIVNVIDINDNPPIFQKKIVNVTIQENTTFPDAILKLNATDLDSGNNAQISYKFSSINRPIIRETFQLQSETGKIYLLKTLDYELYSEQNFDINVLAIDHGSPQLSDSCIIKVNVTDINDNSPVIEIVHS-QPIPENEQITDPA------LKLYVSDYDS-IDNDVKCQAEKIGRRLKLEQVEKSSYFIYATEIYDYEKEKNLSLSILCQDSGKEPRYTKQLLTIFIKDVNDNRPKFLRSFYRKSINEDQEKLKPFTKVQALDKDSDDFGKVKYSIGLKDRKYFSIDEISGEVRLANEIDRETKDFYNVSVIATDGG--GLKDYSYIEISILDVNDNYPKLKSGS-SMRVNENLPVGSVVGYISVIDLDLGDNSKVEWTYDFLGNSSSMLQIENCT--VYTSTVLDRESIEHLHILITMVDMGYPRLTSSATITVSVIDENDNIPKVIYPKTGSLVEEREMDHIAVNSPKYTTVLSIKSFDPDLGINGDVLYHILPSNGSQYFIINQTSG 2260
++GEI T +R D +C G + C ++ V V+P VK+ +IED NDN+P F + ISI EN A +++P A+D D + GI++Y L G V F L + + P L V++S D E + + N +S+T L V V D+NDN P+F++K + V I E+ ++ +L+ATD D G+NA+I + F + + + F + + TG I + + LD E + VLA D S + +N+TDINDN P I+ + P+ Q+++ A + V+D D+ ++ V C + +L+ V + + + DYE + ++ I+ DSGK P +L I IKD NDN P F S E+ TK+ A D DS ++ Y +G F++D +G + ++DRE +D Y +VIA D G L+ + + +S+LD NDN P + V ENLP+ VG I+V D D G+N+ V + L N+ I+ T + + DRE + +D G P+ +S+ +T+ V D NDN P + P D + ++ + V + + D D GIN D+ Y I+ N F I + SG
Sbjct: 98 NTGEIFTTS--NRIDREKLCS--GIFTENKC--FYEVEVAVLPDEVFRLVKIRFLIEDINDNSPLFPSTVINISIPENTAVNSRYSVPSAIDPDVGVNGIQHYELLKGQNV--FGLDVIETPEGDKWPQLIVQQSLDREQKDTYVMKIKVEDGGNPARSSTAILQVTVTDVNDNRPVFKEKDIEVNIPEDAAVGTSVTQLHATDADLGSNAKIHFYFGNQITNLAKRHFAIDNNTGLITVKEPLDRE--ESPYHKLTVLASDGSS--TPSRATVTINITDINDNIPSIDTRYIINPVNGTVQLSEKAPLNTKIALITVTDKDADLNGKVTCFTDH-DVPFRLKPVFDNQFLLETAAPLDYESTREYAIKIVASDSGKPPLNQSAMLLIKIKDENDNAPVFTLPMIGLSFVENNPPGTELTKISATDADSGRNAELSYMLGPNAPTIFNLDRRTGILTAVRKLDREKQDRYTFTVIAKDNGNPSLQTNTTVTLSVLDQNDNSPSFTHNEYNFYVPENLPMYGTVGLITVTDADSGENAVVTLS---LVNARDNFIIDPLTGVIRPNITFDREQQGSYTFQVKALDKGSPQKSSTVKVTIFVEDVNDNKPVFVIPSNN-----YSYDLVQTSTSPGSVVARVYAIDNDTGINADLRYSIIGGNSRGLFAIGERSG 749
BLAST of Protocadherin alpha-2 vs. Ensembl Xenopus
Match: vapa (VAMP associated protein A [Source:Xenbase;Acc:XB-GENE-990155]) HSP 1 Score: 226.483 bits (576), Expect = 2.710e-60 Identity = 219/751 (29.16%), Postives = 359/751 (47.80%), Query Frame = 2
Query: 86 LPSMLIVSFVLISVISAD-IFTARFTIPDNNARHSSVGNIISKLP----SRFPRGSYQIITRRSSFTKFNQYFRISDS-GEIRITKVFDRDDVNNVCGPLGCCDKPSCEIVLDIIVTVIPKNERIPVKVVIVIEDENDNAPDXXXXXXXXXXXXNDATQLDHNLPKALDKDCPIYGIKNYSLSGNKVEYFSLKIRQFQ-----PFLSVKKSFDFENPSEKQFNLSLNAIDNGG---KSATLQLIVNVIDINDNPPIFQKKIVNVTIQENTTFPDAILKLNATDLDSGNNAQISYKFSSINRPIIRETFQLQSETGKIYLLKTLDYELYSEQNFDINVLAIDHGSPQLSDSCIIKVNVTDINDNSPVIEIVH-SQPI------PENEQITDPALKLYVSDYDS-IDNDVKCQAEKIGRRLKLEQVEKSSYFIYATEIYDYEKEKNLSLSILCQDSGKEPRYTKQLLTIFIKDVNDNRPKFLRSFYRKSINEDQEKLKPFTKVQALDKDSDDFGKVKYSIGLKDRKYFSIDEISGEVRLANEIDRETKDFYNVSVIATDGGG--LKDYSYIEISILDVNDNYPKLKSGS-SMRVNENLPVGSVVGYISVIDLDLGDNSKVEWTYDFLG-NSSSMLQIENCTVYTSTVLDRESIEHLHILITMVDMGYPRLTSSATITVSVIDENDNIPKVIYPKTGSLVEEREMDHIAVNSPKYTTVLSIKSFDPDLGINGDVLYHILPSNGSQYFIINQTSG 2260
L + LI L S I+ + I+T R +P+N +GNI L + S ++ R S + ++S S GEI T R D +C D+ C L++++ +P + +K+ I+++D NDNAP F + ISI EN +P A+D D G+++Y L N F L I + P L V+++ D E +K + +++GG KS+T L V V D+NDN P+F++ V V I EN ++++L+ATD D G+NA+I Y F + + F L + TG I + + LD E + + VLA D S + +NVTD+NDN P I++ + PI E + I + VSD D+ +++ V C E+ L+ V + Y + + + DYE K S I+ D+GK L+ + ++D NDN P F + S++E+ + T V A D+DS + Y +G + +F +D +G + + DRE ++ + +V A D G L+ + + +++LD NDN PK V+ENLP S VG I+ D D G+N V T L N + +L + + ++ DRE + VD G P +S+A +T++++D NDN P VI P + + + +++ + V + + D D G+N ++ Y I+ N F I+ +G
Sbjct: 8 LLAALIACLRLDSAIAQELIYTIREELPEN----VPIGNIPKDLNISHINAATGSSTSLVYRLVSKAGDSPLVKVSSSTGEIFTTST--RIDREKLCAGSSNSDENECFFELEVVI--LPNDFFRLIKIKIIVKDTNDNAPMFPSTVINISIPENTLINSRFPIPSAVDPDTGFNGVQHYELL-NGQSVFGLDIVETPEGEKWPQLIVQQNLDRE---QKDTYVMKIKVEDGGTPQKSSTAILQVTVSDVNDNKPVFKESQVEVHIPENAPIGTSVVQLHATDADIGSNAEIKYIFGAQVTSATKRLFALNNTTGLITVQRPLDREETAVHK--LTVLATDGSS--TPARATVTINVTDVNDNPPNIDLRYIISPINGTVYLSEKDPINTKIALITVSDKDTDVNSKVICFIER-EVPFHLKAVYDNQYLLETSSLLDYEGIKEFSFKIVAADTGKPSLNQTALVRVELEDENDNPPIFSQPVIELSVSENNRRGLYLTTVSASDEDSGKNSDIVYQLG-PNASFFDLDRKTGVLTASRVFDREEQERFIFTVTARDNGTPPLQSQAAVIVTVLDENDNSPKFTHNHFQFFVSENLPKYSTVGVITATDSDAGENKAV--TLSILNDNENFVLDPYSGLIKSNVSFDREQQSSYTFDVKAVDGGQPPRSSTAKVTINIMDANDNSPVVISPPSNT-----SFKLVPLSAIPGSVVAEVFAVDTDTGMNAELKYTIVSGNNKGLFRIDPVTG 733 HSP 2 Score: 140.584 bits (353), Expect = 3.945e-33 Identity = 123/469 (26.23%), Postives = 226/469 (48.19%), Query Frame = 2
Query: 665 FLSVKKSFDFENPSEKQFNLSLNAIDNGGKSATLQLIVNVIDINDNPPIFQKKIV------NVTIQENTTFPDAILKLNATDLDSGNNAQISYKFSSINRPIIRETFQLQSETGKIYLLKT---LDYELYSEQNFDINVLAIDHGSPQLSDSCIIKVNVTDINDNSPVIEIVHSQPIPENEQITDPALKLYVSDYDSIDNDVKCQAE---KIGRRLKLEQVEKSSYFIYATEIYDYEKEKNLSLSILCQDSGKEPRYTKQLLTIFIKDVNDNRPKFLRSFYRKSINEDQEKLKPFTKVQALDKDSDDFGKVKYSIGLKDRKYFSIDEISGEVRLANEIDRETKDFYNVSVIATDGGGLKDYSY--IEISILDVNDNYPKLKSGSSMRVNENLPV----GSVVGYISVIDLDLGDNSKVEWTYDFLGNSSSMLQIENCTVYTSTVLDRESIE--HLH-ILITMVDMGYPR 2008
++V++ D E + + L++ A D A + +NV D+NDNPP + + V + E I + +D D+ N+++ I R + F L++ YLL+T LDYE E F ++A D G P L+ + +++V + D NDN P+ SQP+ E + LY++ + D D ++ ++G +++ + + A+ ++D E+++ ++ +D+G P ++ + + + D NDN PKF + ++ ++E+ K + A D D+ + V SI L D + F +D SG ++ DRE + Y V A DGG S + I+I+D NDN P + S S + +P+ GSVV + +D D G N+++++T GN+ + +I+ T T+ ++ S LH +++ + D+GYP+
Sbjct: 311 LITVQRPLDREETAVHK--LTVLATDGSSTPARATVTINVTDVNDNPPNIDLRYIISPINGTVYLSEKDPINTKIALITVSDKDTDVNSKV---ICFIEREV---PFHLKAVYDNQYLLETSSLLDYEGIKE--FSFKIVAADTGKPSLNQTALVRVELEDENDNPPIF----SQPVIELSVSENNRRGLYLTTVSASDEDSGKNSDIVYQLGPNASFFDLDRKTGVLTASRVFDREEQERFIFTVTARDNGTPPLQSQAAVIVTVLDENDNSPKFTHNHFQFFVSENLPKYSTVGVITATDSDAGENKAVTLSI-LNDNENFVLDPYSGLIKSNVSFDREQQSSYTFDVKAVDGGQPPRSSTAKVTINIMDANDNSPVVISPPSNTSFKLVPLSAIPGSVVAEVFAVDTDTGMNAELKYTI-VSGNNKGLFRIDPVT-GNITLEEKPSAADVGLHRLVVNISDLGYPK 762
BLAST of Protocadherin alpha-2 vs. Ensembl Xenopus
Match: ENSXETT00000047798.1 (protocadherin 11 X-linked [Source:NCBI gene;Acc:100493938]) HSP 1 Score: 226.483 bits (576), Expect = 2.717e-60 Identity = 201/673 (29.87%), Postives = 319/673 (47.40%), Query Frame = 2
Query: 299 DSGEIRITKVFDRDDVNNVCGPLGCCDKPSCEIVLDIIVTVIPKNERIPVKVVIVIEDENDNAPDXXXXXXXXXXXXNDATQLDHNLPKALDKDCPIYGIKNYSL-SGNKVEYFSLKIRQFQ-----PFLSVKKSFDFENPSEKQFNLSLNAIDNGGKSATLQLIVNVIDINDNPPIFQKKIVNVTIQENTTFPDAILKLNATDLDSGNNAQISYKFSSINRPIIRETFQLQSETGKIYLLKTLDYELYSEQNFDINVLAIDHGSPQLSDSCIIKVNVTDINDNSPVIEIVHS-QPIPENEQITDPA------LKLYVSDYDS-IDNDVKCQAEKIGRRLKLEQVEKSSYFIYATEIYDYEKEKNLSLSILCQDSGKEPRYTKQLLTIFIKDVNDNRPKFLRSFYRKSINEDQEKLKPFTKVQALDKDSDDFGKVKYSIGLKDRKYFSIDEISGEVRLANEIDRETKDFYNVSVIATDGG--GLKDYSYIEISILDVNDNYPKLKSGS-SMRVNENLPVGSVVGYISVIDLDLGDNSKVEWTYDFLGNSSSMLQIENCT--VYTSTVLDRESIEHLHILITMVDMGYPRLTSSATITVSVIDENDNIPKVIYPKTGSLVEEREMDHIAVNSPKYTTVLSIKSFDPDLGINGDVLYHILPSNGSQYFIINQTSG 2260
++GEI T +R D +C G + C ++ V V+P VK+ +IED NDN+P F + ISI EN A +++P A+D D + GI++Y L G V F L + + P L V++S D E + + N +S+T L V V D+NDN P+F++K + V I E+ ++ +L+ATD D G+NA+I + F + + + F + + TG I + + LD E + VLA D S + +N+TDINDN P I+ + P+ Q+++ A + V+D D+ ++ V C + +L+ V + + + DYE + ++ I+ DSGK P +L I IKD NDN P F S E+ TK+ A D DS ++ Y +G F++D +G + ++DRE +D Y +VIA D G L+ + + +S+LD NDN P + V ENLP+ VG I+V D D G+N+ V + L N+ I+ T + + DRE + +D G P+ +S+ +T+ V D NDN P + P D + ++ + V + + D D GIN D+ Y I+ N F I + SG
Sbjct: 78 NTGEIFTTS--NRIDREKLCS--GIFTENKC--FYEVEVAVLPDEVFRLVKIRFLIEDINDNSPLFPSTVINISIPENTAVNSRYSVPSAIDPDVGVNGIQHYELLKGQNV--FGLDVIETPEGDKWPQLIVQQSLDREQKDTYVMKIKVEDGGNPARSSTAILQVTVTDVNDNRPVFKEKDIEVNIPEDAAVGTSVTQLHATDADLGSNAKIHFYFGNQITNLAKRHFAIDNNTGLITVKEPLDRE--ESPYHKLTVLASDGSS--TPSRATVTINITDINDNIPSIDTRYIINPVNGTVQLSEKAPLNTKIALITVTDKDADLNGKVTCFTDH-DVPFRLKPVFDNQFLLETAAPLDYESTREYAIKIVASDSGKPPLNQSAMLLIKIKDENDNAPVFTLPMIGLSFVENNPPGTELTKISATDADSGRNAELSYMLGPNAPTIFNLDRRTGILTAVRKLDREKQDRYTFTVIAKDNGNPSLQTNTTVTLSVLDQNDNSPSFTHNEYNFYVPENLPMYGTVGLITVTDADSGENAVVTLS---LVNARDNFIIDPLTGVIRPNITFDREQQGSYTFQVKALDKGSPQKSSTVKVTIFVEDVNDNKPVFVIPSNN-----YSYDLVQTSTSPGSVVARVYAIDNDTGINADLRYSIIGGNSRGLFAIGERSG 729
BLAST of Protocadherin alpha-2 vs. Ensembl Xenopus
Match: ENSXETT00000047801.1 (protocadherin 11 X-linked [Source:NCBI gene;Acc:100493938]) HSP 1 Score: 226.483 bits (576), Expect = 2.858e-60 Identity = 201/673 (29.87%), Postives = 319/673 (47.40%), Query Frame = 2
Query: 299 DSGEIRITKVFDRDDVNNVCGPLGCCDKPSCEIVLDIIVTVIPKNERIPVKVVIVIEDENDNAPDXXXXXXXXXXXXNDATQLDHNLPKALDKDCPIYGIKNYSL-SGNKVEYFSLKIRQFQ-----PFLSVKKSFDFENPSEKQFNLSLNAIDNGGKSATLQLIVNVIDINDNPPIFQKKIVNVTIQENTTFPDAILKLNATDLDSGNNAQISYKFSSINRPIIRETFQLQSETGKIYLLKTLDYELYSEQNFDINVLAIDHGSPQLSDSCIIKVNVTDINDNSPVIEIVHS-QPIPENEQITDPA------LKLYVSDYDS-IDNDVKCQAEKIGRRLKLEQVEKSSYFIYATEIYDYEKEKNLSLSILCQDSGKEPRYTKQLLTIFIKDVNDNRPKFLRSFYRKSINEDQEKLKPFTKVQALDKDSDDFGKVKYSIGLKDRKYFSIDEISGEVRLANEIDRETKDFYNVSVIATDGG--GLKDYSYIEISILDVNDNYPKLKSGS-SMRVNENLPVGSVVGYISVIDLDLGDNSKVEWTYDFLGNSSSMLQIENCT--VYTSTVLDRESIEHLHILITMVDMGYPRLTSSATITVSVIDENDNIPKVIYPKTGSLVEEREMDHIAVNSPKYTTVLSIKSFDPDLGINGDVLYHILPSNGSQYFIINQTSG 2260
++GEI T +R D +C G + C ++ V V+P VK+ +IED NDN+P F + ISI EN A +++P A+D D + GI++Y L G V F L + + P L V++S D E + + N +S+T L V V D+NDN P+F++K + V I E+ ++ +L+ATD D G+NA+I + F + + + F + + TG I + + LD E + VLA D S + +N+TDINDN P I+ + P+ Q+++ A + V+D D+ ++ V C + +L+ V + + + DYE + ++ I+ DSGK P +L I IKD NDN P F S E+ TK+ A D DS ++ Y +G F++D +G + ++DRE +D Y +VIA D G L+ + + +S+LD NDN P + V ENLP+ VG I+V D D G+N+ V + L N+ I+ T + + DRE + +D G P+ +S+ +T+ V D NDN P + P D + ++ + V + + D D GIN D+ Y I+ N F I + SG
Sbjct: 98 NTGEIFTTS--NRIDREKLCS--GIFTENKC--FYEVEVAVLPDEVFRLVKIRFLIEDINDNSPLFPSTVINISIPENTAVNSRYSVPSAIDPDVGVNGIQHYELLKGQNV--FGLDVIETPEGDKWPQLIVQQSLDREQKDTYVMKIKVEDGGNPARSSTAILQVTVTDVNDNRPVFKEKDIEVNIPEDAAVGTSVTQLHATDADLGSNAKIHFYFGNQITNLAKRHFAIDNNTGLITVKEPLDRE--ESPYHKLTVLASDGSS--TPSRATVTINITDINDNIPSIDTRYIINPVNGTVQLSEKAPLNTKIALITVTDKDADLNGKVTCFTDH-DVPFRLKPVFDNQFLLETAAPLDYESTREYAIKIVASDSGKPPLNQSAMLLIKIKDENDNAPVFTLPMIGLSFVENNPPGTELTKISATDADSGRNAELSYMLGPNAPTIFNLDRRTGILTAVRKLDREKQDRYTFTVIAKDNGNPSLQTNTTVTLSVLDQNDNSPSFTHNEYNFYVPENLPMYGTVGLITVTDADSGENAVVTLS---LVNARDNFIIDPLTGVIRPNITFDREQQGSYTFQVKALDKGSPQKSSTVKVTIFVEDVNDNKPVFVIPSNN-----YSYDLVQTSTSPGSVVARVYAIDNDTGINADLRYSIIGGNSRGLFAIGERSG 749
BLAST of Protocadherin alpha-2 vs. Ensembl Xenopus
Match: pcdh17 (protocadherin 17 [Source:Xenbase;Acc:XB-GENE-480220]) HSP 1 Score: 220.32 bits (560), Expect = 3.144e-58 Identity = 192/631 (30.43%), Postives = 304/631 (48.18%), Query Frame = 2
Query: 458 IVIEDENDNAPDXXXXXXXXXXXXNDATQLDHNLPKALDKDCPIYGIKNYSL--SGNKVEYFSLKIRQ----FQPFLSVKKSFDFENPSEKQFNLSLNAIDNG--GKSATLQLIVNVIDINDNPPIFQKKIVNVTIQENTTFPDAILKLNATDLDSGNNAQISYKFSSINRPIIRETFQLQSETGKIYLLKTLDYELYSEQNFDINVLAIDHGSPQLSDSCIIKVNVTDINDNSPVIEI-----VHSQP----IPENEQITDPALKLYVSDYD-SIDNDVKCQAEKIGRRLKLEQVE------KSSYFIYATEIYDYEKEKNLSLSILCQDSGKEPRYTKQLLTIFIKDVNDNRPKFLRSFYRKSINEDQEKLKPFTKVQALDKDSDDFGKVKYSIGLKD---RKYFSIDEISGEVRLANEIDRETKDFYNVSVIATDGG--GLKDYSYIEISILDVNDNYPK-LKSGSSMRVNENLPVGSVVGYISVIDLDLGDNSKVEWTYDFLGNSSSMLQIENCTVYTSTVLDRESIEHLHILITMVDMGYPRLTSSATITVSVIDENDNIPKVIYPKTGSLVEEREMDHIAVNSPKYTTVLSIKSFDPDLGINGDVLYHILPSNGSQYFIINQTSG 2260
I I D NDN P+F+ T+SI EN + +P A D+D + G+ +Y L + F L++ + QP L V D E ++L++ D G ++++ L ++++D NDN P F+K + EN+ ++L++ A D D G NA+I Y F + +R L TG I + +D E F +V+A D G+ + + + + D NDN PVIEI V Q I E+ + P + VSD D ++ V C +L+QV K YF+ T DYE K ++ I+ DSG P + L + + DVNDN P F +S E+ + +V A D DS ++ YSI L D R FSI+ SG++R+ +DRE ++ Y+ V+A D G LK + + I++LD NDN PK + +G + V EN+P S VG ++VID D G+N+ + + + + ++Q T+ +S DRE + VD G P +S +T++V+DENDN P ++ P S ++ + T V +++ D D GIN ++ Y I N + F I+ +G
Sbjct: 164 IEIMDINDNTPNFNSPVITLSIPENTNIGMLFPIPAATDRDSGVNGVSSYELIVGPEAQDLFGLQVAEDQDEKQPQLIVMGMLDREQ--RDSYDLTIKVQDGGTPARASSALLRISILDTNDNAPKFEKMAYEAELPENSPMGHSVLQVKANDSDQGVNAEIDYSFHQASD-TVRRLLHLDRSTGLITVQGPIDREDVGTLKF--SVVAKDKGANPKTARTQVTITIRDTNDNKPVIEIRGFGLVTHQGGVANISEDVPVETPVALVQVSDIDEGVNAAVTCVVAG-DVPFQLKQVSDTGSDSKKKYFLQTTTALDYESVKEYTIEIVAVDSGNPPLSSTNSLKVQVTDVNDNAPVFSQSLMEVVFPENNDINDLVMEVSATDADSGPNSQLHYSI-LPDPSARGIFSINPDSGQIRVNTVLDREQREHYDFHVVAVDKGIPSLKGTASVVITVLDRNDNDPKFMLNGYNFSVMENMPRLSPVGMVTVIDADKGENAHIHLSVE-PESGEFVIQNGTGTILSSISFDREHQSTYTFRLKAVDGGDPPRSSYVGVTINVLDENDNAPVIVVPSNISY------KYLTPQTHPGTPVNWVRAEDMDTGINAELDYSIASGNPFELFQISHNNG 780 HSP 2 Score: 125.561 bits (314), Expect = 1.587e-28 Identity = 139/506 (27.47%), Postives = 218/506 (43.08%), Query Frame = 2
Query: 902 GNNAQISYKFSSINRPIIRETFQLQSETGKIYLLKTLDYELYSEQNFDINVLAIDHGSPQLSDSCIIKVNVTDIND-----NSPVIEIVHSQPIPENEQITDPALKLYVSDYDSIDNDVKC-------QAEKI-GRRLKLEQVEKSSYFIYATEIYDYEKEKNLSLSILCQDSGKEPRYTKQLLTIFIKDVNDNRPKFLRSFYRKSINEDQEKLKPFTKVQALDKDSDDFGKVKYSIGLKD---RKYFSIDEISGEVRLANEIDRETKDFYNVSVIATDGGG--LKDYSYIEISILDVNDNYPKLK---------SGSSMRVNENLPVGSVVGYISVIDLDLGDNSKVEWTYDFLGNSSSMLQIENCT---------VYTSTVLDRESIEHLHILITMVDMGYPRLTSSATITVSVIDENDNIP-------KVIYPKTGSLVEEREMDHIAVNSPKYTTVLSIKSFDPDLGINGDVLYHILPSNGSQ-YFIINQTSGVLKTTWIYD 2287
G I +SI+R +RE L E G+ L+ F++++ + P+L D ++ + DIND NSPVI + IPEN I +D DS N V +A+ + G ++ +Q EK I + D E+ + L+I QD G R + LL I I D NDN PKF + Y + E+ +V+A D D ++ YS R+ +D +G + + IDRE SV+A D G + + I+I D NDN P ++ G ++E++PV + V + V D+D G N+ V T G+ L+ + T + T+T LD ES++ I I VD G P L+S+ ++ V V D NDN P +V++P+ + + V+ + + D D G N + Y ILP ++ F IN SG ++ + D
Sbjct: 112 GKTGDIYTTETSIDRESLRECQNL--EPGEKCFLE-----------FEVSMTDLMSPVPRLLDG---QIEIMDINDNTPNFNSPVITLS----IPENTNIGMLFPIPAATDRDSGVNGVSSYELIVGPEAQDLFGLQVAEDQDEKQPQLI-VMGMLDREQRDSYDLTIKVQDGGTPARASSALLRISILDTNDNAPKFEKMAYEAELPENSPMGHSVLQVKANDSDQGVNAEIDYSFHQASDTVRRLLHLDRSTGLITVQGPIDREDVGTLKFSVVAKDKGANPKTARTQVTITIRDTNDNKPVIEIRGFGLVTHQGGVANISEDVPVETPVALVQVSDIDEGVNAAV--TCVVAGDVPFQLKQVSDTGSDSKKKYFLQTTTALDYESVKEYTIEIVAVDSGNPPLSSTNSLKVQVTDVNDNAPVFSQSLMEVVFPENNDIND---------------LVMEVSATDADSGPNSQLHYSILPDPSARGIFSINPDSGQIRVNTVLD 579 HSP 3 Score: 116.316 bits (290), Expect = 1.201e-25 Identity = 98/351 (27.92%), Postives = 166/351 (47.29%), Query Frame = 2
Query: 665 FLSVKKSFDFENPSEKQFNLSLNAIDNGGK--SATLQLIVNVIDINDNPPIFQKKIVNVTIQENTTFPDAILKLNATDLDSGNNAQISYKFSSINRPIIRETFQLQSETGKIYLLKTLDYELYSEQNFDINVLAIDHGSPQLSDSCIIKVNVTDINDNSPVIEI-VHSQPIPENEQITDPALKLYVSDYDSIDN-DVKCQAEKIGRRLKLEQVEKSSYFIYATEIYDYEKEKNLSLSILCQDSGKEPRYTKQLLTIFIKDVNDNRPKFL--RSFYRKSINEDQEKLKPFTKVQALDKDSDDFGKVKYSIGLKDR-KYFSIDEISGEVRLANEIDRETKDFYNVSVIATDGG 1696
FL + D+E S K++ + + A+D+G S+T L V V D+NDN P+F + ++ V EN D +++++ATD DSG N+Q+ Y S + P R F + ++G+I + LD E +++D +V+A+D G P L + + + V D NDN P + ++ + EN P + V D D +N + E ++ + I ++ +D E + + + D G PR + +TI + D NDN P + + K + P V+A D D+ ++ YSI + + F I +GEV L I R+ + + V TD G
Sbjct: 465 FLQTTTALDYE--SVKEYTIEIVAVDSGNPPLSSTNSLKVQVTDVNDNAPVFSQSLMEVVFPENNDINDLVMEVSATDADSGPNSQLHY--SILPDPSARGIFSINPDSGQIRVNTVLDRE--QREHYDFHVVAVDKGIPSLKGTASVVITVLDRNDNDPKFMLNGYNFSVMENMPRLSPVGMVTVIDADKGENAHIHLSVEPESGEFV---IQNGTGTILSSISFDREHQSTYTFRLKAVDGGDPPRSSYVGVTINVLDENDNAPVIVVPSNISYKYLTPQTHPGTPVNWVRAEDMDTGINAELDYSIASGNPFELFQISHNNGEVTLEKAIIRKHYGLHRLVVKVTDKG 806
BLAST of Protocadherin alpha-2 vs. Ensembl Mouse
Match: Pcdh11x (protocadherin 11 X-linked [Source:MGI Symbol;Acc:MGI:2442849]) HSP 1 Score: 248.054 bits (632), Expect = 3.249e-67 Identity = 214/673 (31.80%), Postives = 327/673 (48.59%), Query Frame = 2
Query: 302 SGEIRITKVFDRDDVNNVCGPLGCCDKPSCEIVLDIIVTVIPKNERIPVKVVIVIEDENDNAPDXXXXXXXXXXXXNDATQLDHNLPKALDKDCPIYGIKNYSLSGNKVEYFSLKIRQF-----QPFLSVKKSFDFENPSEKQFNLSLNAIDNGG---KSATLQLIVNVIDINDNPPIFQKKIVNVTIQENTTFPDAILKLNATDLDSGNNAQISYKFSSINRPIIRETFQLQSETGKIYLLKTLDYELYSEQNFDINVLAIDHGSPQLSDSCIIKVNVTDINDNSPVIEIVH-------SQPIPENEQITDPALKLYVSDYDSIDND-VKCQAEKIGRRLKLEQVEKSSYFIYATEIYDYEKEKNLSLSILCQDSGKEPRYTKQLLTIFIKDVNDNRPKFLRSFYRKSINEDQEKLKPFTKVQALDKDSDDFGKVKYSIGLKDRKYFSIDEISGEVRLANEIDRETKDFYNVSVIATDGG--GLKDYSYIEISILDVNDNYPKLKSGS-SMRVNENLPVGSVVGYISVIDLDLGDNSKVEWTYDFLG-NSSSMLQIENCTVYTSTVLDRESIEHLHILITMVDMGYPRLTSSATITVSVIDENDNIPKVIYPKTGSLVEEREMDHIAVNSPKYTTVLSIKSFDPDLGINGDVLYHILPSNGSQYFIINQTSG 2260
+GEI T R D +C G C ++ V V+P VK+ +IED NDNAP F + ISI EN A ++LP A+D D I G++NY L ++ F L + + P L V+K D E EK + +++GG +S+T L V+V D NDN PIF +K + V+I EN ++ +L+ATD D G NA+I + FS++ I + F L + TG I + + LD E + + VLA D GS + VNVTDINDN P I+I + + + EN + + V D DS N V C + +L V + + + D+E + ++ +L D+GK P +L I +KD NDN P F +SF S+ E+ TK+ A D DS ++ Y +G F++D+ +G + ++DRE ++ Y +V+A D G L + + +++LD NDN P + V E+LP VG I+V D D G+NS V T L N + ++ + + DRE E + D G +S+A +T++V+D NDN P I P + + + ++ T V + + D D+G+N +VLY I+ N F+I QTSG
Sbjct: 81 TGEIFTTGA--RIDREKLCA--GIVLDARC--FYEVEVAVLPDEIFRLVKIRFLIEDINDNAPLFPTTVINISIPENSAINSRYSLPAAIDPDIGINGVQNYQLIKSQ-NIFGLDVIETPEGDKMPQLIVQKELDRE---EKDTYVMKVKVEDGGFPQRSSTAILQVSVADTNDNHPIFIEKEIEVSIPENAPIGSSVTQLHATDADIGENARIHFYFSNLVSNIAKRLFHLNTTTGLITVKEPLDRE--ESPSHKLLVLATDGGS--TPARATVLVNVTDINDNVPSIDIRYIVNPTNGTVLLSENAPLNTKIALITVMDKDSEHNGRVTCFTDH-EVPFRLRPVFSNQFLLETAAFLDFESTREYAIKLLAADAGKPPLNQSSMLLIKVKDENDNAPVFTQSFISLSVPENNSPGAQLTKISATDADSGQNAEISYMLGFDAPPEFNLDQRTGILTAVKKLDREKQEKYYFTVLAQDNGIPPLMSNATVFVTVLDQNDNSPIFTHNEYNFYVPESLPKHGTVGLITVTDPDYGENSAV--TLSILDVNDQFTIDPQSGVIRPNISFDRERQESYTFYVKAEDGGRVSRSSTARVTINVVDVNDNKPIFIDPPSN-----YSFEWVLPSTNPGTVVFKVVAIDDDIGMNAEVLYSIVGGNTKGLFMIEQTSG 731
BLAST of Protocadherin alpha-2 vs. Ensembl Mouse
Match: Pcdh11x (protocadherin 11 X-linked [Source:MGI Symbol;Acc:MGI:2442849]) HSP 1 Score: 246.899 bits (629), Expect = 3.548e-67 Identity = 214/673 (31.80%), Postives = 328/673 (48.74%), Query Frame = 2
Query: 302 SGEIRITKVFDRDDVNNVCGPLGCCDKPSCEIVLDIIVTVIPKNERIPVKVVIVIEDENDNAPDXXXXXXXXXXXXNDATQLDHNLPKALDKDCPIYGIKNYSLSGNKVEYFSLKIRQF-----QPFLSVKKSFDFENPSEKQFNLSLNAIDNGG---KSATLQLIVNVIDINDNPPIFQKKIVNVTIQENTTFPDAILKLNATDLDSGNNAQISYKFSSINRPIIRETFQLQSETGKIYLLKTLDYELYSEQNFDINVLAIDHGSPQLSDSCIIKVNVTDINDNSPVIEIVH-------SQPIPENEQITDPALKLYVSDYDSIDND-VKCQAEKIGRRLKLEQVEKSSYFIYATEIYDYEKEKNLSLSILCQDSGKEPRYTKQLLTIFIKDVNDNRPKFLRSFYRKSINEDQEKLKPFTKVQALDKDSDDFGKVKYSIGLKDRKYFSIDEISGEVRLANEIDRETKDFYNVSVIATDGG--GLKDYSYIEISILDVNDNYPKLKSGS-SMRVNENLPVGSVVGYISVIDLDLGDNSKVEWTYDFLG-NSSSMLQIENCTVYTSTVLDRESIEHLHILITMVDMGYPRLTSSATITVSVIDENDNIPKVIYPKTGSLVEEREMDHIAVNSPKYTTVLSIKSFDPDLGINGDVLYHILPSNGSQYFIINQTSG 2260
+GEI T R D +C G C ++ V V+P VK+ +IED NDNAP F + ISI EN A ++LP A+D D I G++NY L ++ F L + + P L V+K D E EK + +++GG +S+T L V+V D NDN PIF +K + V+I EN ++ +L+ATD D G NA+I + FS++ I + F L + TG I + + LD E + + VLA D GS + + VNVTDINDN P I+I + + + EN + + V D DS N V C + +L V + + + D+E + ++ +L D+GK P +L I +KD NDN P F +SF S+ E+ TK+ A D DS ++ Y +G F++D+ +G + ++DRE ++ Y +V+A D G L + + +++LD NDN P + V E+LP VG I+V D D G+NS V T L N + ++ + + DRE E + D G +S+A +T++V+D NDN P I P + + + ++ T V + + D D+G+N +VLY I+ N F+I QTSG
Sbjct: 81 TGEIFTTGA--RIDREKLCA--GIVLDARC--FYEVEVAVLPDEIFRLVKIRFLIEDINDNAPLFPTTVINISIPENSAINSRYSLPAAIDPDIGINGVQNYQLIKSQ-NIFGLDVIETPEGDKMPQLIVQKELDRE---EKDTYVMKVKVEDGGFPQRSSTAILQVSVADTNDNHPIFIEKEIEVSIPENAPIGSSVTQLHATDADIGENARIHFYFSNLVSNIAKRLFHLNTTTGLITVKEPLDRE--ESPSHKLLVLATDGGSTPARATVL--VNVTDINDNVPSIDIRYIVNPTNGTVLLSENAPLNTKIALITVMDKDSEHNGRVTCFTDH-EVPFRLRPVFSNQFLLETAAFLDFESTREYAIKLLAADAGKPPLNQSSMLLIKVKDENDNAPVFTQSFISLSVPENNSPGAQLTKISATDADSGQNAEISYMLGFDAPPEFNLDQRTGILTAVKKLDREKQEKYYFTVLAQDNGIPPLMSNATVFVTVLDQNDNSPIFTHNEYNFYVPESLPKHGTVGLITVTDPDYGENSAV--TLSILDVNDQFTIDPQSGVIRPNISFDRERQESYTFYVKAEDGGRVSRSSTARVTINVVDVNDNKPIFIDPPSN-----YSFEWVLPSTNPGTVVFKVVAIDDDIGMNAEVLYSIVGGNTKGLFMIEQTSG 731
BLAST of Protocadherin alpha-2 vs. Ensembl Mouse
Match: Pcdh11x (protocadherin 11 X-linked [Source:MGI Symbol;Acc:MGI:2442849]) HSP 1 Score: 246.899 bits (629), Expect = 2.047e-66 Identity = 215/673 (31.95%), Postives = 327/673 (48.59%), Query Frame = 2
Query: 302 SGEIRITKVFDRDDVNNVCGPLGCCDKPSCEIVLDIIVTVIPKNERIPVKVVIVIEDENDNAPDXXXXXXXXXXXXNDATQLDHNLPKALDKDCPIYGIKNYSLSGNKVEYFSLKIRQF-----QPFLSVKKSFDFENPSEKQFNLSLNAIDNGG---KSATLQLIVNVIDINDNPPIFQKKIVNVTIQENTTFPDAILKLNATDLDSGNNAQISYKFSSINRPIIRETFQLQSETGKIYLLKTLDYELYSEQNFDINVLAIDHGSPQLSDSCIIKVNVTDINDNSPVIEIVH-------SQPIPENEQITDPALKLYVSDYDSIDND-VKCQAEKIGRRLKLEQVEKSSYFIYATEIYDYEKEKNLSLSILCQDSGKEPRYTKQLLTIFIKDVNDNRPKFLRSFYRKSINEDQEKLKPFTKVQALDKDSDDFGKVKYSIGLKDRKYFSIDEISGEVRLANEIDRETKDFYNVSVIATDGG--GLKDYSYIEISILDVNDNYPKLKSGS-SMRVNENLPVGSVVGYISVIDLDLGDNSKVEWTYDFLG-NSSSMLQIENCTVYTSTVLDRESIEHLHILITMVDMGYPRLTSSATITVSVIDENDNIPKVIYPKTGSLVEEREMDHIAVNSPKYTTVLSIKSFDPDLGINGDVLYHILPSNGSQYFIINQTSG 2260
+GEI T R D +C G C ++ V V+P VK+ +IED NDNAP F + ISI EN A ++LP A+D D I G++NY L ++ F L + + P L V+K D E EK + +++GG +S+T L V+V D NDN PIF +K + V+I EN ++ +L+ATD D G NA+I + FS++ I + F L + TG I + + LD E + + VLA D GS + VNVTDINDN P I+I + + + EN + + V D DS N V C + +L V + + + D+E + ++ +L D+GK P +L I +KD NDN P F +SF S+ E+ TK+ A D DS ++ Y +G F++D+ +G + ++DRE ++ Y +V+A D G L + + +++LD NDN P + V E+LP VG I+V D D G+NS V T L N + ++ + + DRE E + D G +S+A +T++V+D NDN P I P + E + ++ T V + + D D+G+N +VLY I+ N F+I QTSG
Sbjct: 81 TGEIFTTGA--RIDREKLCA--GIVLDARC--FYEVEVAVLPDEIFRLVKIRFLIEDINDNAPLFPTTVINISIPENSAINSRYSLPAAIDPDIGINGVQNYQLIKSQ-NIFGLDVIETPEGDKMPQLIVQKELDRE---EKDTYVMKVKVEDGGFPQRSSTAILQVSVADTNDNHPIFIEKEIEVSIPENAPIGSSVTQLHATDADIGENARIHFYFSNLVSNIAKRLFHLNTTTGLITVKEPLDRE--ESPSHKLLVLATDGGS--TPARATVLVNVTDINDNVPSIDIRYIVNPTNGTVLLSENAPLNTKIALITVMDKDSEHNGRVTCFTDH-EVPFRLRPVFSNQFLLETAAFLDFESTREYAIKLLAADAGKPPLNQSSMLLIKVKDENDNAPVFTQSFISLSVPENNSPGAQLTKISATDADSGQNAEISYMLGFDAPPEFNLDQRTGILTAVKKLDREKQEKYYFTVLAQDNGIPPLMSNATVFVTVLDQNDNSPIFTHNEYNFYVPESLPKHGTVGLITVTDPDYGENSAV--TLSILDVNDQFTIDPQSGVIRPNISFDRERQESYTFYVKAEDGGRVSRSSTARVTINVVDVNDNKPIFIDPPSNYSFE-----WVLPSTNPGTVVFKVVAIDDDIGMNAEVLYSIVGGNTKGLFMIEQTSG 731
BLAST of Protocadherin alpha-2 vs. Ensembl Mouse
Match: Pcdh11x (protocadherin 11 X-linked [Source:MGI Symbol;Acc:MGI:2442849]) HSP 1 Score: 246.514 bits (628), Expect = 2.182e-66 Identity = 214/673 (31.80%), Postives = 327/673 (48.59%), Query Frame = 2
Query: 302 SGEIRITKVFDRDDVNNVCGPLGCCDKPSCEIVLDIIVTVIPKNERIPVKVVIVIEDENDNAPDXXXXXXXXXXXXNDATQLDHNLPKALDKDCPIYGIKNYSLSGNKVEYFSLKIRQF-----QPFLSVKKSFDFENPSEKQFNLSLNAIDNGG---KSATLQLIVNVIDINDNPPIFQKKIVNVTIQENTTFPDAILKLNATDLDSGNNAQISYKFSSINRPIIRETFQLQSETGKIYLLKTLDYELYSEQNFDINVLAIDHGSPQLSDSCIIKVNVTDINDNSPVIEIVH-------SQPIPENEQITDPALKLYVSDYDSIDND-VKCQAEKIGRRLKLEQVEKSSYFIYATEIYDYEKEKNLSLSILCQDSGKEPRYTKQLLTIFIKDVNDNRPKFLRSFYRKSINEDQEKLKPFTKVQALDKDSDDFGKVKYSIGLKDRKYFSIDEISGEVRLANEIDRETKDFYNVSVIATDGG--GLKDYSYIEISILDVNDNYPKLKSGS-SMRVNENLPVGSVVGYISVIDLDLGDNSKVEWTYDFLG-NSSSMLQIENCTVYTSTVLDRESIEHLHILITMVDMGYPRLTSSATITVSVIDENDNIPKVIYPKTGSLVEEREMDHIAVNSPKYTTVLSIKSFDPDLGINGDVLYHILPSNGSQYFIINQTSG 2260
+GEI T R D +C G C ++ V V+P VK+ +IED NDNAP F + ISI EN A ++LP A+D D I G++NY L ++ F L + + P L V+K D E EK + +++GG +S+T L V+V D NDN PIF +K + V+I EN ++ +L+ATD D G NA+I + FS++ I + F L + TG I + + LD E + + VLA D GS + VNVTDINDN P I+I + + + EN + + V D DS N V C + +L V + + + D+E + ++ +L D+GK P +L I +KD NDN P F +SF S+ E+ TK+ A D DS ++ Y +G F++D+ +G + ++DRE ++ Y +V+A D G L + + +++LD NDN P + V E+LP VG I+V D D G+NS V T L N + ++ + + DRE E + D G +S+A +T++V+D NDN P I P + + + ++ T V + + D D+G+N +VLY I+ N F+I QTSG
Sbjct: 81 TGEIFTTGA--RIDREKLCA--GIVLDARC--FYEVEVAVLPDEIFRLVKIRFLIEDINDNAPLFPTTVINISIPENSAINSRYSLPAAIDPDIGINGVQNYQLIKSQ-NIFGLDVIETPEGDKMPQLIVQKELDRE---EKDTYVMKVKVEDGGFPQRSSTAILQVSVADTNDNHPIFIEKEIEVSIPENAPIGSSVTQLHATDADIGENARIHFYFSNLVSNIAKRLFHLNTTTGLITVKEPLDRE--ESPSHKLLVLATDGGS--TPARATVLVNVTDINDNVPSIDIRYIVNPTNGTVLLSENAPLNTKIALITVMDKDSEHNGRVTCFTDH-EVPFRLRPVFSNQFLLETAAFLDFESTREYAIKLLAADAGKPPLNQSSMLLIKVKDENDNAPVFTQSFISLSVPENNSPGAQLTKISATDADSGQNAEISYMLGFDAPPEFNLDQRTGILTAVKKLDREKQEKYYFTVLAQDNGIPPLMSNATVFVTVLDQNDNSPIFTHNEYNFYVPESLPKHGTVGLITVTDPDYGENSAV--TLSILDVNDQFTIDPQSGVIRPNISFDRERQESYTFYVKAEDGGRVSRSSTARVTINVVDVNDNKPIFIDPPSN-----YSFEWVLPSTNPGTVVFKVVAIDDDIGMNAEVLYSIVGGNTKGLFMIEQTSG 731
BLAST of Protocadherin alpha-2 vs. Ensembl Mouse
Match: Pcdh11x (protocadherin 11 X-linked [Source:MGI Symbol;Acc:MGI:2442849]) HSP 1 Score: 246.514 bits (628), Expect = 2.342e-66 Identity = 215/673 (31.95%), Postives = 327/673 (48.59%), Query Frame = 2
Query: 302 SGEIRITKVFDRDDVNNVCGPLGCCDKPSCEIVLDIIVTVIPKNERIPVKVVIVIEDENDNAPDXXXXXXXXXXXXNDATQLDHNLPKALDKDCPIYGIKNYSLSGNKVEYFSLKIRQF-----QPFLSVKKSFDFENPSEKQFNLSLNAIDNGG---KSATLQLIVNVIDINDNPPIFQKKIVNVTIQENTTFPDAILKLNATDLDSGNNAQISYKFSSINRPIIRETFQLQSETGKIYLLKTLDYELYSEQNFDINVLAIDHGSPQLSDSCIIKVNVTDINDNSPVIEIVH-------SQPIPENEQITDPALKLYVSDYDSIDND-VKCQAEKIGRRLKLEQVEKSSYFIYATEIYDYEKEKNLSLSILCQDSGKEPRYTKQLLTIFIKDVNDNRPKFLRSFYRKSINEDQEKLKPFTKVQALDKDSDDFGKVKYSIGLKDRKYFSIDEISGEVRLANEIDRETKDFYNVSVIATDGG--GLKDYSYIEISILDVNDNYPKLKSGS-SMRVNENLPVGSVVGYISVIDLDLGDNSKVEWTYDFLG-NSSSMLQIENCTVYTSTVLDRESIEHLHILITMVDMGYPRLTSSATITVSVIDENDNIPKVIYPKTGSLVEEREMDHIAVNSPKYTTVLSIKSFDPDLGINGDVLYHILPSNGSQYFIINQTSG 2260
+GEI T R D +C G C ++ V V+P VK+ +IED NDNAP F + ISI EN A ++LP A+D D I G++NY L ++ F L + + P L V+K D E EK + +++GG +S+T L V+V D NDN PIF +K + V+I EN ++ +L+ATD D G NA+I + FS++ I + F L + TG I + + LD E + + VLA D GS + VNVTDINDN P I+I + + + EN + + V D DS N V C + +L V + + + D+E + ++ +L D+GK P +L I +KD NDN P F +SF S+ E+ TK+ A D DS ++ Y +G F++D+ +G + ++DRE ++ Y +V+A D G L + + +++LD NDN P + V E+LP VG I+V D D G+NS V T L N + ++ + + DRE E + D G +S+A +T++V+D NDN P I P + E + ++ T V + + D D+G+N +VLY I+ N F+I QTSG
Sbjct: 81 TGEIFTTGA--RIDREKLCA--GIVLDARC--FYEVEVAVLPDEIFRLVKIRFLIEDINDNAPLFPTTVINISIPENSAINSRYSLPAAIDPDIGINGVQNYQLIKSQ-NIFGLDVIETPEGDKMPQLIVQKELDRE---EKDTYVMKVKVEDGGFPQRSSTAILQVSVADTNDNHPIFIEKEIEVSIPENAPIGSSVTQLHATDADIGENARIHFYFSNLVSNIAKRLFHLNTTTGLITVKEPLDRE--ESPSHKLLVLATDGGS--TPARATVLVNVTDINDNVPSIDIRYIVNPTNGTVLLSENAPLNTKIALITVMDKDSEHNGRVTCFTDH-EVPFRLRPVFSNQFLLETAAFLDFESTREYAIKLLAADAGKPPLNQSSMLLIKVKDENDNAPVFTQSFISLSVPENNSPGAQLTKISATDADSGQNAEISYMLGFDAPPEFNLDQRTGILTAVKKLDREKQEKYYFTVLAQDNGIPPLMSNATVFVTVLDQNDNSPIFTHNEYNFYVPESLPKHGTVGLITVTDPDYGENSAV--TLSILDVNDQFTIDPQSGVIRPNISFDRERQESYTFYVKAEDGGRVSRSSTARVTINVVDVNDNKPIFIDPPSNYSFE-----WVLPSTNPGTVVFKVVAIDDDIGMNAEVLYSIVGGNTKGLFMIEQTSG 731
BLAST of Protocadherin alpha-2 vs. UniProt/SwissProt
Match: sp|Q9BZA7|PC11X_HUMAN (Protocadherin-11 X-linked OS=Homo sapiens OX=9606 GN=PCDH11X PE=2 SV=1) HSP 1 Score: 252.677 bits (644), Expect = 1.734e-67 Identity = 227/679 (33.43%), Postives = 332/679 (48.90%), Query Frame = 2
Query: 299 DSGEIRITKVFDRDDVNNVCGPLGCCDKPSCEIVLDIIVTVIPKNERIPVKVVIVIEDENDNAPDXXXXXXXXXXXXNDATQLDHNLPKALDKDCPIYGIKNYSLSGNKVEYFSLKIRQF-----QPFLSVKKSFDFENPSEKQFNLSLNAIDNGG---KSATLQLIVNVIDINDNPPIFQKKIVNVTIQENTTFPDAILKLNATDLDSGNNAQISYKFSSINRPIIRETFQLQSETGKIYLLKTLDYELYSEQNFDINVLAIDHGSPQLSDSCIIKVNVTDINDNSPVIEI-----------VHSQPIPENEQITDPALKLYVSDYDSIDND-VKCQAE-KIGRRLKLEQVEKSSYFIYATEIYDYEKEKNLSLSILCQDSGKEPRYTKQLLTIFIKDVNDNRPKFLRSFYRKSINEDQEKLKPFTKVQALDKDSDDFGKVKYSIGLKDRKYFSIDEISGEVRLANEIDRETKDFYNVSVIATDGG--GLKDYSYIEISILDVNDNYPKLKSGS-SMRVNENLPVGSVVGYISVIDLDLGDNSKVEWTYDFLG-NSSSMLQIENCTVYTSTVLDRESIEHLHILITMVDMGYPRLTSSATITVSVIDENDNIPKVIYPKTGSLVEEREMDHIAVNSPKYTTVLSIKSFDPDLGINGDVLYHILPSNGSQYFIINQTSG 2260
D+GEI T R D +C G C ++ V ++P VK+ +IED NDNAP F + ISI EN A + LP A+D D I G++NY L ++ F L + + P L V+K D E EK + +++GG +S+T L V+V D NDN P+F++ + V+I EN ++ +L+ATD D G NA+I + FS++ I R F L + TG I + + LD E N + VLA D G + ++ VNVTD+NDN P I+I V S+ IP N +I AL + V+D D+ N V C + +I RL+ V + + + DYE K ++ +L D+GK P +L I +KD NDN P F +SF SI E+ TKV A+D DS K+ Y +G FS+D +G + + ++DRE +D Y +++A D G L + +SI+D NDN P + V ENLP VG I+V D D GDNS V T L N + + + + DRE E + D G +SSA +T++V+D NDN P I P + E + ++ T V + + D D G+N +V Y I+ N F I+Q +G
Sbjct: 80 DTGEIFTTGA--RIDREKLCA--GIPRDEHC--FYEVEVAILPDEIFRLVKIRFLIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGINGVQNYELIKSQ-NIFGLDVIETPEGDKMPQLIVQKELDRE---EKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATTGLITIKEPLDRE--ETPNHKLLVLASDGG--LMPARAMVLVNVTDVNDNVPSIDIRYIVNPVNDTVVLSENIPLNTKI---AL-ITVTDKDADHNGRVTCFTDHEIPFRLR--PVFSNQFLLETAAYLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQLTKVSAMDADSGPNAKINYLLGPDAPPEFSLDCRTGMLTVVKKLDREKEDKYLFTILAKDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYNFYVPENLPRHGTVGLITVTDPDYGDNSAV--TLSILDENDDFTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSSAKVTINVVDVNDNKPVFIVPPSNCSYE-----LVLPSTNPGTVVFQVIAVDNDTGMNAEVRYSIVGGNTRDLFAIDQETG 731
BLAST of Protocadherin alpha-2 vs. UniProt/SwissProt
Match: sp|Q6WXV7|PC11X_PONPY (Protocadherin-11 X-linked OS=Pongo pygmaeus OX=9600 GN=PCDH11X PE=3 SV=1) HSP 1 Score: 250.366 bits (638), Expect = 9.765e-67 Identity = 226/679 (33.28%), Postives = 331/679 (48.75%), Query Frame = 2
Query: 299 DSGEIRITKVFDRDDVNNVCGPLGCCDKPSCEIVLDIIVTVIPKNERIPVKVVIVIEDENDNAPDXXXXXXXXXXXXNDATQLDHNLPKALDKDCPIYGIKNYSLSGNKVEYFSLKIRQF-----QPFLSVKKSFDFENPSEKQFNLSLNAIDNGG---KSATLQLIVNVIDINDNPPIFQKKIVNVTIQENTTFPDAILKLNATDLDSGNNAQISYKFSSINRPIIRETFQLQSETGKIYLLKTLDYELYSEQNFDINVLAIDHGSPQLSDSCIIKVNVTDINDNSPVIEI-----------VHSQPIPENEQITDPALKLYVSDYDSIDND-VKCQAE-KIGRRLKLEQVEKSSYFIYATEIYDYEKEKNLSLSILCQDSGKEPRYTKQLLTIFIKDVNDNRPKFLRSFYRKSINEDQEKLKPFTKVQALDKDSDDFGKVKYSIGLKDRKYFSIDEISGEVRLANEIDRETKDFYNVSVIATDGG--GLKDYSYIEISILDVNDNYPKLKSGS-SMRVNENLPVGSVVGYISVIDLDLGDNSKVEWTYDFLG-NSSSMLQIENCTVYTSTVLDRESIEHLHILITMVDMGYPRLTSSATITVSVIDENDNIPKVIYPKTGSLVEEREMDHIAVNSPKYTTVLSIKSFDPDLGINGDVLYHILPSNGSQYFIINQTSG 2260
D+GEI T R D +C G C ++ V ++P VK+ +IED NDNAP F + ISI EN A + LP A+D D I G++NY L ++ F L + + P L V+K D E EK + +++GG +S+T L V+V D NDN P+F++ + V+I EN ++ +L+ATD D G NA+I + FS++ I R F L + TG I + + LD E N + VLA D G + ++ VNVTD+NDN P I+I V S+ IP N +I AL + V+D D+ N V C + +I RL+ V + + + DYE K ++ +L D+GK P +L I +KD NDN P F +SF SI E+ TKV A D DS ++ Y +G FS+D +G + + ++DRE +D Y +++A D G L + +SI+D NDN P + V ENLP VG I+V D D GDNS V T L N + + + + DRE E + D G +SSA +T++V+D NDN P I P + E + ++ T V + + D D G+N +V Y I+ N F I+Q +G
Sbjct: 80 DTGEIFTTGA--RIDREKLCA--GIPRDEHC--FYEVEVAILPDEIFRLVKIRFLIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGINGVQNYELIKSQ-NIFGLDVIETPEGDKMPQLIVQKELDRE---EKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATTGLITIKEPLDRE--ETPNHKLLVLASDGG--LMPARAMVLVNVTDVNDNVPSIDIRYIVNPINDTVVLSENIPLNTKI---AL-ITVTDKDADHNGRVTCFTDHEIPFRLR--PVFSNQFLLETAAYLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQLTKVSATDADSGPNAEINYLLGPDAPPEFSLDRRTGMLTVVKKLDREKEDKYLFTILAKDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYNFYVPENLPRHGTVGLITVTDPDYGDNSAV--TLSILDENDDFTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSSAKVTINVVDVNDNKPVFIVPPSNYSYE-----LVLPSTNPGTVVFQVIAVDNDTGMNAEVRYSIVGGNTRDLFAIDQETG 731
BLAST of Protocadherin alpha-2 vs. UniProt/SwissProt
Match: sp|Q71M42|PC11X_PANTR (Protocadherin-11 X-linked OS=Pan troglodytes OX=9598 GN=PCDH11X PE=3 SV=1) HSP 1 Score: 249.595 bits (636), Expect = 2.070e-66 Identity = 225/679 (33.14%), Postives = 330/679 (48.60%), Query Frame = 2
Query: 299 DSGEIRITKVFDRDDVNNVCGPLGCCDKPSCEIVLDIIVTVIPKNERIPVKVVIVIEDENDNAPDXXXXXXXXXXXXNDATQLDHNLPKALDKDCPIYGIKNYSLSGNKVEYFSLKIRQF-----QPFLSVKKSFDFENPSEKQFNLSLNAIDNGG---KSATLQLIVNVIDINDNPPIFQKKIVNVTIQENTTFPDAILKLNATDLDSGNNAQISYKFSSINRPIIRETFQLQSETGKIYLLKTLDYELYSEQNFDINVLAIDHGSPQLSDSCIIKVNVTDINDNSPVIEI-----------VHSQPIPENEQITDPALKLYVSDYDSIDND-VKCQAE-KIGRRLKLEQVEKSSYFIYATEIYDYEKEKNLSLSILCQDSGKEPRYTKQLLTIFIKDVNDNRPKFLRSFYRKSINEDQEKLKPFTKVQALDKDSDDFGKVKYSIGLKDRKYFSIDEISGEVRLANEIDRETKDFYNVSVIATDGG--GLKDYSYIEISILDVNDNYPKLKSGS-SMRVNENLPVGSVVGYISVIDLDLGDNSKVEWTYDFLG-NSSSMLQIENCTVYTSTVLDRESIEHLHILITMVDMGYPRLTSSATITVSVIDENDNIPKVIYPKTGSLVEEREMDHIAVNSPKYTTVLSIKSFDPDLGINGDVLYHILPSNGSQYFIINQTSG 2260
D+GEI T R D +C G C ++ V ++P VK+ +IED NDNAP F + ISI EN A + LP A+D D G++NY L ++ F L + + P L V+K D E EK + +++GG +S+T L V+V D NDN P+F++ + V+I EN ++ +L+ATD D G NA+I + FS++ I R F L + TG I + + LD E N + VLA D G + ++ VNVTD+NDN P I+I V S+ IP N +I AL + V+D D+ N V C + +I RL+ V + + + DYE K ++ +L D+GK P +L I +KD NDN P F +SF SI E+ TKV A D DS ++ Y +G FS+D +G + + ++DRE +D Y +++A D G L + +SI+D NDN P + V ENLP VG I+V D D GDNS V T L N + + + + DRE E + D G +SSA +T++V+D NDN P I P + E + ++ T V + + D D G+N +V Y I+ N F I+Q +G
Sbjct: 80 DTGEIFTTGA--RIDREKLCA--GIPRDEHC--FYEVEVAILPDEIFRLVKIRFLIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGTNGVQNYELIKSQ-NIFGLDVIETPEGDKMPQLIVQKELDRE---EKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATTGLITIKEPLDRE--ETPNHKLLVLASDGG--LMPARAMVLVNVTDVNDNVPSIDIRYIVNPVNDTVVLSENIPLNTKI---AL-ITVTDKDADHNGRVTCFTDHEIPFRLR--PVFSNQFLLETAAYLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQLTKVSATDADSGPNAEINYLLGPDAPPEFSLDRRTGMLTVVKKLDREKEDKYLFTILAKDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYNFYVPENLPRHGTVGLITVTDPDYGDNSAV--TLSILDENDDFTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSSAKVTINVVDVNDNKPVFIVPPSNYSYE-----LVLPSTNPGTVVFQVMAVDNDTGMNAEVRYSIVGGNTRDLFAIDQETG 731
BLAST of Protocadherin alpha-2 vs. UniProt/SwissProt
Match: sp|Q6WYY1|PC11X_PANPA (Protocadherin-11 X-linked OS=Pan paniscus OX=9597 GN=PCDH11X PE=3 SV=1) HSP 1 Score: 249.21 bits (635), Expect = 2.325e-66 Identity = 225/679 (33.14%), Postives = 330/679 (48.60%), Query Frame = 2
Query: 299 DSGEIRITKVFDRDDVNNVCGPLGCCDKPSCEIVLDIIVTVIPKNERIPVKVVIVIEDENDNAPDXXXXXXXXXXXXNDATQLDHNLPKALDKDCPIYGIKNYSLSGNKVEYFSLKIRQF-----QPFLSVKKSFDFENPSEKQFNLSLNAIDNGG---KSATLQLIVNVIDINDNPPIFQKKIVNVTIQENTTFPDAILKLNATDLDSGNNAQISYKFSSINRPIIRETFQLQSETGKIYLLKTLDYELYSEQNFDINVLAIDHGSPQLSDSCIIKVNVTDINDNSPVIEI-----------VHSQPIPENEQITDPALKLYVSDYDSIDND-VKCQAE-KIGRRLKLEQVEKSSYFIYATEIYDYEKEKNLSLSILCQDSGKEPRYTKQLLTIFIKDVNDNRPKFLRSFYRKSINEDQEKLKPFTKVQALDKDSDDFGKVKYSIGLKDRKYFSIDEISGEVRLANEIDRETKDFYNVSVIATDGG--GLKDYSYIEISILDVNDNYPKLKSGS-SMRVNENLPVGSVVGYISVIDLDLGDNSKVEWTYDFLG-NSSSMLQIENCTVYTSTVLDRESIEHLHILITMVDMGYPRLTSSATITVSVIDENDNIPKVIYPKTGSLVEEREMDHIAVNSPKYTTVLSIKSFDPDLGINGDVLYHILPSNGSQYFIINQTSG 2260
D+GEI T R D +C G C ++ V ++P VK+ +IED NDNAP F + ISI EN A + LP A+D D G++NY L ++ F L + + P L V+K D E EK + +++GG +S+T L V+V D NDN P+F++ + V+I EN ++ +L+ATD D G NA+I + FS++ I R F L + TG I + + LD E N + VLA D G + ++ VNVTD+NDN P I+I V S+ IP N +I AL + V+D D+ N V C + +I RL+ V + + + DYE K ++ +L D+GK P +L I +KD NDN P F +SF SI E+ TKV A D DS ++ Y +G FS+D +G + + ++DRE +D Y +++A D G L + +SI+D NDN P + V ENLP VG I+V D D GDNS V T L N + + + + DRE E + D G +SSA +T++V+D NDN P I P + E + ++ T V + + D D G+N +V Y I+ N F I+Q +G
Sbjct: 80 DTGEIFTTGA--RIDREKLCA--GIPRDEHC--FYEVEVAILPDEIFRLVKIRFLIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGTNGVQNYELIKSQ-NIFGLDVIETPEGDKMPQLIVQKELDRE---EKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATTGLITIKEPLDRE--ETPNHKLLVLASDGG--LMPARAMVLVNVTDVNDNVPSIDIRYIVNPVNDTVVLSENIPLNTKI---AL-ITVTDKDADHNGRVTCFTDHEIPFRLR--PVFSNQFLLETAAYLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQLTKVSATDADSGPNAEINYLLGPDAPPEFSLDRRTGMLTVVKKLDREKEDKYLFTILAKDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYNFYVPENLPRHGTVGLITVTDPDYGDNSAV--TLSILDENDDFTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSSAKVTINVVDVNDNKPVFIVPPSNYSYE-----LVLPSTNPGTVVFQVMAVDNDTGMNAEVRYSIVGGNTRDLFAIDQETG 731
BLAST of Protocadherin alpha-2 vs. UniProt/SwissProt
Match: sp|Q6X862|PC11X_GORGO (Protocadherin-11 X-linked OS=Gorilla gorilla gorilla OX=9595 GN=PCDH11X PE=3 SV=1) HSP 1 Score: 248.44 bits (633), Expect = 4.155e-66 Identity = 225/679 (33.14%), Postives = 331/679 (48.75%), Query Frame = 2
Query: 299 DSGEIRITKVFDRDDVNNVCGPLGCCDKPSCEIVLDIIVTVIPKNERIPVKVVIVIEDENDNAPDXXXXXXXXXXXXNDATQLDHNLPKALDKDCPIYGIKNYSLSGNKVEYFSLKIRQF-----QPFLSVKKSFDFENPSEKQFNLSLNAIDNGG---KSATLQLIVNVIDINDNPPIFQKKIVNVTIQENTTFPDAILKLNATDLDSGNNAQISYKFSSINRPIIRETFQLQSETGKIYLLKTLDYELYSEQNFDINVLAIDHGSPQLSDSCIIKVNVTDINDNSPVIEI-----------VHSQPIPENEQITDPALKLYVSDYDSIDND-VKCQAE-KIGRRLKLEQVEKSSYFIYATEIYDYEKEKNLSLSILCQDSGKEPRYTKQLLTIFIKDVNDNRPKFLRSFYRKSINEDQEKLKPFTKVQALDKDSDDFGKVKYSIGLKDRKYFSIDEISGEVRLANEIDRETKDFYNVSVIATDGG--GLKDYSYIEISILDVNDNYPKLKSGS-SMRVNENLPVGSVVGYISVIDLDLGDNSKVEWTYDFLG-NSSSMLQIENCTVYTSTVLDRESIEHLHILITMVDMGYPRLTSSATITVSVIDENDNIPKVIYPKTGSLVEEREMDHIAVNSPKYTTVLSIKSFDPDLGINGDVLYHILPSNGSQYFIINQTSG 2260
D+GEI T R D +C G C ++ V ++P VK+ +IED NDNAP F + ISI EN A + LP A+D D I G++NY L ++ F L + + P L V+K D E +K + +++GG +S+T L V+V D NDN P+F++ + V+I EN ++ +L+ATD D G NA+I + FS++ I R F L + TG I + + LD E N + VLA D G + ++ VNVTD+NDN P I+I V S+ IP N +I AL + V+D D+ N V C + +I RL+ V + + + DYE K ++ +L D+GK P +L I +KD NDN P F +SF SI E+ TKV A D DS ++ Y +G FS+D +G + + ++DRE +D Y +++A D G L + +SI+D NDN P + V ENLP VG I+V D D GDNS V T L N + + + + DRE E + D G +SSA +T++V+D NDN P I P + E + ++ T V + + D D G+N +V Y I+ N F I+Q +G
Sbjct: 80 DTGEIFTTGA--RIDREKLCA--GIPRDEHC--FYEVEVAILPDEIFRLVKIRFLIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGINGVQNYELIKSQ-NMFGLDVIETPEGDKMPQLIVQKELDRE---KKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATTGLITIKEPLDRE--ETPNHKLLVLASDGG--LMPARAMVLVNVTDVNDNVPSIDIRYIVNPVNDTVVLSENIPLNTKI---AL-ITVTDKDADHNGRVTCFTDHEIPFRLR--PVFSNQFLLETAAYLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQLTKVSATDADSGPNAEINYLLGPDAPPEFSLDRRTGMLTVVKKLDREKEDKYLFTILAKDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYNFYVPENLPRHGTVGLITVTDPDYGDNSAV--TLSILDENDDFTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSSAKVTINVVDVNDNKPVFIVPPSNYSYE-----LVLPSTNPGTVVFQVIAVDNDTGMNAEVRYSIVGGNTRDLFAIDQETG 731
BLAST of Protocadherin alpha-2 vs. TrEMBL
Match: A0A0R3WAJ9 (Uncharacterized protein OS=Taenia asiatica OX=60517 GN=TASK_LOCUS7587 PE=4 SV=2) HSP 1 Score: 362.844 bits (930), Expect = 1.525e-104 Identity = 247/788 (31.35%), Postives = 396/788 (50.25%), Query Frame = 2
Query: 146 TARFTIPDNNARHSSVGNIISKLPSRFPRGSYQ---IITRRSSFTKFNQYFRISDSGEIRITKVFDRDDVNNVCGPLGCCDKPSCEIVLDIIVTV-------IPKNERIPVKVVIVIEDENDNAP----DXXXXXXXXXXXXNDATQLDHNLPKALDKDCPIYGIKNYSLSGNK--VEYFSLK--------------IRQFQPFLSVKKSFDFENPSEKQFNLSLNAIDNGGKSATLQLIVNVI--DINDNPPIFQKK-IVNVTIQENTTF-PDAILKLNATDLDSGNNAQISYKFSSINRPIIRETFQLQSETGKIYLLKTLDYELYSEQNFDINVLAIDHGSPQLSDSCIIKVNVTDINDNSPVIEIVHSQPIPENEQITDPALKLYVSDYDSID-NDVKC-----QAEKIGR-RLKLEQVEKSSYFIYATEIYDYEKEKNLSLSILCQDSGKEPRYTKQLL--TIFIKDVNDNRPKFLRSFYRKSINEDQEKLKPFTKVQALDKDSDDFGKVKYSIGLKD------RKYFSIDEISGEVRLANE--IDRETKDFYNVSVIATDGGGLKDYSYIEISILDVNDNYPKLKSGSSMRVNENLPVGSVVGYISVIDLDLGDNSKVEW------------TYDFLGNSSS-------------MLQIENCTVYTSTVLDRESIEHLHILITMVDMGYPRLTSSATITVSVIDENDNIPKVIYPKTGSLVEEREMDHIAVNSPKYTTVLSIKSFDPDLGINGDVLYHILP-SNGSQYFIINQTSGVLKTTW 2278
+A F + D +VGNI L +P+ S I+ S F +FN+YF I+ +G I K DRD++N++CGPL CC C I ++ V + ++++ + I + D NDN+P + + A LP A+D D G+ Y + N + F L R P L + D+ENP++++F L + AID G + T L V V+ DINDN P+F++ I ++ + ENTT+ PD + K ATD+DS +N I+Y S +N P++ E F + +G +YL LDYE+YSE+ F + V+A D+G+P+ S + + V D+NDN P + + + + E T P ++ YV D D + V C +A+ +G L+L++V ++YF++ I+DYE+ ++ S+ I+C D+ +++L T+ I D ND+ P+F + + + E K K +V A D D+ ++ YS+ + ++ F+ID +G V + N +DRE + V A DGGGL + + I ++D+NDN P ++ S+ V ENLP G VVG + D D+G N+++ +D + S S M I V T LDRE IE I D G P+ + ++ V V+DENDN+P + +P+ + V + NSP + V ++S+DPD G NG V+Y + +NGS+YF ++QT+G L T W
Sbjct: 17 SATFQMVDEIKPGQTVGNICHAL---WPKSSIAFSLIVVTSSRFQRFNEYFSITKNGSIIAQKFVDRDNINDICGPLDCCQSAICIIHARVMFIVEQSENPVMHSHDQVLAHLQIHLTDINDNSPRFPLNSQGYPHFTIRIQEGAKFAREMLPSAVDLDSAGNGVVQYRIEANSPSTDLFQLTYEKVLINPPSESHGWRLSPPTLIQLRELDYENPADREFELVVIAIDGGEPALTGSLSVTVVLMDINDNAPVFERTNISSIELAENTTYSPDPVYKFLATDMDSADNGLITYSLSPLNEPMVFEKFAIDGRSGALYLNSILDYEVYSERRFTVIVVASDNGTPKRSGTTTLTVVTKDVNDNLPSLVVQENITVIEGLNYTKPVVRFYVKDDDYVSRGKVICRPAPNRAKGVGSASLRLQEVTTNAYFVFTEGIFDYEEARSASVEIICSDTADSFNTRERILPITVAIGDANDHYPEFGVTEFLAKLPEHSPKGKRVVQVTASDADAGIHARLTYSLVSSNGGRCSIQEIFNIDSATGVVTVKNSECLDREVNEEIEAYVAAEDGGGLSTSAKLRIRLMDINDNSPSIQVPDSLSVTENLPAGVVVGRVRCTDADIGSNAEIRLELSANNTQQVRNAFDTISESGSARNSFFSRGKVRGMNDITGLLV-TKKPLDREDIESYTIQFVATDSGTPQRITYKSVQVLVLDENDNVPVLRFPQLDTTVGYHP--QVYTNSPYGSKVCVLRSYDPDKGENGTVIYALQHDTNGSRYFQLDQTTGELTTAW 798
BLAST of Protocadherin alpha-2 vs. TrEMBL
Match: A0A5K3F286 (Uncharacterized protein OS=Mesocestoides corti OX=53468 PE=4 SV=1) HSP 1 Score: 355.14 bits (910), Expect = 1.759e-101 Identity = 254/792 (32.07%), Postives = 390/792 (49.24%), Query Frame = 2
Query: 155 FTIPDNNARHSSVGNIISKLPSRFPRGSYQIITRRSSFTKFNQYFRISDSGEIRITKVFDRDDVNNVCGPLGCCDKPSCEIVLDIIVTV-------IPKNERIPVKVVIVIEDENDNAP----DXXXXXXXXXXXXNDATQLDHNLPKALDKDCPIYGIKNYSLSGNKV------EYFSLK--------------IRQFQPFLSVKKSFDFENPSEKQFNLSLNAIDNGGKSAT--LQLIVNVIDINDNPPIFQKK-IVNVTIQENTTF-PDAILKLNATDLDSGNNAQISYKFSSINRPIIRETFQLQSETGKIYLLKTLDYELYSEQNFDINVLAIDHGSPQLSDSCIIKVNVTDINDNSPVIEIVHSQPIPENEQITDPALKLYVSDYDSID-NDVKC-----QAEKIG-----RRLKLEQVEKSSYFIYATEIYDYEKEKNLSLSILCQDSG-KEPRYTKQ---LLTIFIKDVNDNRPKFLRSFYRKSINEDQEKLKPFTKVQALDKDSDDFGKVKYSI------GLKDRKYFSIDEISG--EVRLANEIDRETKDFYNVSVIATDGGGLKDYSYIEISILDVNDNYPKLKSGSSMRVNENLPVGSVVGYISVIDLDLGDNS------------KVEWTYDFL-------------GNSSSMLQIENCTVYTSTVLDRESIEHLHILITMVDMGYPRLTSSATITVSVIDENDNIPKVIYPKTGSLVEEREMDHIAVNSPKYTTVLSIKSFDPDLGINGDVLYHILP-SNGSQYFIINQTSGVLKTTW 2278
F I D ++GNI L + ++ S+F +FN+YF I+ +G + + K+ DRD++++VCGPL CC C I ++ V + N+++P + + + D NDN+P + + + LP A+D D GI Y LS +K E F L R P L + DFE P+++QF L + AID G + T L + VN++DINDN PIF+K + + + ENTTF P+ I K ATDLDSG N ISY S +N P + + F + + G +YL+ LDYE+YSE++F + +A D+G+P+ S + + V DINDN P + + + + E T P ++ YV D D + V C +A + G L+L++V ++YF++ I+DYE+ K+ S+ I+C D EP + +T+ I D ND+ P+F S + + E + ++ A D DS +V YS+ + SID +G V+ N +DRE + V A DGGGL ++I ++DVNDN P+ + S V EN P G V+G + D D+G NS V+ ++D L G S ++ + + T LDRE +E I + DMG P L + TI + V+DENDN P +P+ + V + H NSP + V ++S DPD G NG V+Y I P +NGS+ F +++ +G L T W
Sbjct: 48 FEIIDEVKPGHTIGNIRQVLWQKSSTVFSLVVVTSSNFQRFNEYFSITKNGTVIVQKLVDRDNLDDVCGPLDCCQSAVCTIDARVMFIVDQNEDSSVSSNDQLPAHLQLRLVDVNDNSPQFPLNSNGRPEFTVRIQEGGKFARETLPSAVDLDSAENGIVQYRLSSDKNPNHSTDELFRLSYEKVLSDPLNKSQGWRLSPPMLIQLRELDFEVPTDRQFKLIVIAIDGGNPALTGSLSVTVNLMDINDNSPIFEKTNVSTIELAENTTFSPNPIHKFIATDLDSGENGLISYSLSPLNEPRVFDKFSIDNSNGALYLISALDYEVYSERHFTVIAVASDNGTPKRSGTTTLTVVTRDINDNLPTLVVQENITVIEGINYTKPVVRFYVKDDDFVSRGKVTCRPSPSRATEAGIAAGAASLRLQEVTANAYFVFTEGIFDYEETKSASVEIVCSDRALGEPLTSPDRPIRITVAIGDANDHYPEFGVSEFLTKLPEHSPEGTRIARLTATDADSGLNSRVTYSLVNDNGGRCSTLEALSIDRQTGVVSVKNGNCLDREANEEVEAFVAAEDGGGLSTSVKLKIRLMDVNDNEPRFQVTDSFSVPENRPGGFVIGSVRCTDADVGVNSGILLELSENNTQSVKESFDLLLSEGLSPNVVPGRGKVSGRGEV-SAVLVTKKRLDREEVETYTIQLVATDMGEPPLRAHKTIHLVVLDENDNQPIPRFPQPFTTVGYHPLVH--TNSPYGSKVCVLRSHDPDRGENGTVVYDIQPGTNGSRDFHLDRVTGALTTMW 836
BLAST of Protocadherin alpha-2 vs. TrEMBL
Match: A0A158QVI0 (Uncharacterized protein OS=Mesocestoides corti OX=53468 GN=MCOS_LOCUS7977 PE=4 SV=1) HSP 1 Score: 355.525 bits (911), Expect = 1.999e-101 Identity = 254/792 (32.07%), Postives = 390/792 (49.24%), Query Frame = 2
Query: 155 FTIPDNNARHSSVGNIISKLPSRFPRGSYQIITRRSSFTKFNQYFRISDSGEIRITKVFDRDDVNNVCGPLGCCDKPSCEIVLDIIVTV-------IPKNERIPVKVVIVIEDENDNAP----DXXXXXXXXXXXXNDATQLDHNLPKALDKDCPIYGIKNYSLSGNKV------EYFSLK--------------IRQFQPFLSVKKSFDFENPSEKQFNLSLNAIDNGGKSAT--LQLIVNVIDINDNPPIFQKK-IVNVTIQENTTF-PDAILKLNATDLDSGNNAQISYKFSSINRPIIRETFQLQSETGKIYLLKTLDYELYSEQNFDINVLAIDHGSPQLSDSCIIKVNVTDINDNSPVIEIVHSQPIPENEQITDPALKLYVSDYDSID-NDVKC-----QAEKIG-----RRLKLEQVEKSSYFIYATEIYDYEKEKNLSLSILCQDSG-KEPRYTKQ---LLTIFIKDVNDNRPKFLRSFYRKSINEDQEKLKPFTKVQALDKDSDDFGKVKYSI------GLKDRKYFSIDEISG--EVRLANEIDRETKDFYNVSVIATDGGGLKDYSYIEISILDVNDNYPKLKSGSSMRVNENLPVGSVVGYISVIDLDLGDNS------------KVEWTYDFL-------------GNSSSMLQIENCTVYTSTVLDRESIEHLHILITMVDMGYPRLTSSATITVSVIDENDNIPKVIYPKTGSLVEEREMDHIAVNSPKYTTVLSIKSFDPDLGINGDVLYHILP-SNGSQYFIINQTSGVLKTTW 2278
F I D ++GNI L + ++ S+F +FN+YF I+ +G + + K+ DRD++++VCGPL CC C I ++ V + N+++P + + + D NDN+P + + + LP A+D D GI Y LS +K E F L R P L + DFE P+++QF L + AID G + T L + VN++DINDN PIF+K + + + ENTTF P+ I K ATDLDSG N ISY S +N P + + F + + G +YL+ LDYE+YSE++F + +A D+G+P+ S + + V DINDN P + + + + E T P ++ YV D D + V C +A + G L+L++V ++YF++ I+DYE+ K+ S+ I+C D EP + +T+ I D ND+ P+F S + + E + ++ A D DS +V YS+ + SID +G V+ N +DRE + V A DGGGL ++I ++DVNDN P+ + S V EN P G V+G + D D+G NS V+ ++D L G S ++ + + T LDRE +E I + DMG P L + TI + V+DENDN P +P+ + V + H NSP + V ++S DPD G NG V+Y I P +NGS+ F +++ +G L T W
Sbjct: 83 FEIIDEVKPGHTIGNIRQVLWQKSSTVFSLVVVTSSNFQRFNEYFSITKNGTVIVQKLVDRDNLDDVCGPLDCCQSAVCTIDARVMFIVDQNEDSSVSSNDQLPAHLQLRLVDVNDNSPQFPLNSNGRPEFTVRIQEGGKFARETLPSAVDLDSAENGIVQYRLSSDKNPNHSTDELFRLSYEKVLSDPLNKSQGWRLSPPMLIQLRELDFEVPTDRQFKLIVIAIDGGNPALTGSLSVTVNLMDINDNSPIFEKTNVSTIELAENTTFSPNPIHKFIATDLDSGENGLISYSLSPLNEPRVFDKFSIDNSNGALYLISALDYEVYSERHFTVIAVASDNGTPKRSGTTTLTVVTRDINDNLPTLVVQENITVIEGINYTKPVVRFYVKDDDFVSRGKVTCRPSPSRATEAGIAAGAASLRLQEVTANAYFVFTEGIFDYEETKSASVEIVCSDRALGEPLTSPDRPIRITVAIGDANDHYPEFGVSEFLTKLPEHSPEGTRIARLTATDADSGLNSRVTYSLVNDNGGRCSTLEALSIDRQTGVVSVKNGNCLDREANEEVEAFVAAEDGGGLSTSVKLKIRLMDVNDNEPRFQVTDSFSVPENRPGGFVIGSVRCTDADVGVNSGILLELSENNTQSVKESFDLLLSEGLSPNVVPGRGKVSGRGEV-SAVLVTKKRLDREEVETYTIQLVATDMGEPPLRAHKTIHLVVLDENDNQPIPRFPQPFTTVGYHPLVH--TNSPYGSKVCVLRSHDPDRGENGTVVYDIQPGTNGSRDFHLDRVTGALTTMW 871
BLAST of Protocadherin alpha-2 vs. TrEMBL
Match: A0A0R3TU25 (Uncharacterized protein OS=Rodentolepis nana OX=102285 GN=HNAJ_LOCUS11230 PE=4 SV=1) HSP 1 Score: 350.903 bits (899), Expect = 4.857e-100 Identity = 252/784 (32.14%), Postives = 383/784 (48.85%), Query Frame = 2
Query: 146 TARFTIPDNNARHSSVGNIISKLPSRFPRGSYQIITRRSSFTKFNQYFRISDSGEIRITKVFDRDDVNNVCGPLGCCDKPSCEIVLDIIVTV-------IPKNERIPVKVVIVIEDENDNAP----DXXXXXXXXXXXXNDATQLDHNLPKALDKDCPIYGIKNYSLSGNK--VEYFSLK--------------IRQFQPFLSVKKSFDFENPSEKQFNLSLNAIDNGGKSATLQLIVNVI--DINDNPPIFQKK-IVNVTIQENTTF-PDAILKLNATDLDSGNNAQISYKFSSINRPIIRETFQLQSETGKIYLLKTLDYELYSEQNFDINVLAIDHGSPQLSDSCIIKVNVTDINDNSPVIEIVHSQPIPENEQITDPALKLYVSDYDSID-NDVKCQAE-----KIGR-RLKLEQVEKSSYFIYATEIYDYEKEKNLSLSILCQDSGKEPRYTKQLL--TIFIKDVNDNRPKFLRSFYRKSINEDQEKLKPFTKVQALDKDSDDFGKVKYSI------GLKDRKYFSIDEISGEVRLANE--IDRETKDFYNVSVIATDGGGLKDYSYIEISILDVNDNYPKLKSGSSMRVNENLPVGSVVGYISVIDLDLGDNSK------------VEWTYDF------LGN----SSSMLQIENCT--VYTSTVLDRESIEHLHILITMVDMGYPRLTSSATITVSVIDENDNIPKVIYPKTGSLVEEREMDHIAVNSPKYTTVLSIKSFDPDLGINGDVLYHILP-SNGSQYFIINQTSGVLKTTW 2278
TA F + D ++GNI + L R I+ S F +FN+YF I +G I K DRD+VN++CGPL CC P C I ++ V I ++++ + I + D NDN P + + A LP A+D D G+ Y + N + F L R P L + D+ENP+++QF L + AID G S T L V VI D+NDN P F+K I + + ENTT+ PD I K A+D DSG N I+Y S +N P + E F + G ++L LDYE+YSE++F + V+A D+G+P+ S + + + DINDN P + + + + E T P ++ YV D DS+ V C+ +IG L+L++V ++YF++A I+DYE+ S+ I+C D QLL T+ + D ND+ P+F + + + E +V A D D K+ YS+ + ID ++G V + N +DRE D + A DGGGL + + ++D+NDN P ++ S+ V+EN P G VVG I DLD G N+K V +D LGN +++ + + T + T LDRE +E +I + D+G P+ + T+ V V+DENDN P + +P+ + V + NSP + V ++S DPD G NG V+Y + +NGS++F + Q++G L T W
Sbjct: 26 TATFQMVDEIKTGENIGNICNSLWPNSNRVFSLIVVTYSRFQRFNEYFSIFKNGTIIAQKHVDRDNVNDICGPLDCCQSPVCTIQAKVMFIVEQSDSGTIRAHDQMMAHLQIHLTDINDNPPKFPLNSLGFPLFTIRIQEGAKFAREMLPSAIDLDSVGNGVVQYRIEANSPSADLFQLTYEKVLINSLNESHGWRLSPPTLLQLRELDYENPADRQFELVVLAIDGGEPSHTGSLSVTVILMDVNDNTPQFEKTTITTIELAENTTYSPDPIYKFAASDADSGENGLITYSLSPLNDPKVFENFSIDRRLGALHLNTLLDYEVYSERSFSVIVVASDNGTPKRSGTTTLTIVTKDINDNLPSLVVQENITVIEGLNYTKPVVRFYVKDDDSVSRGKVFCRPAPTTPMRIGLPSLRLQEVTTNAYFVFAEGIFDYEETHYASVGIICTDRTDPTNAPDQLLHITVAVGDSNDHYPEFAVAEFHAKLLEHSPVGTRVIQVVATDADEGIHAKLTYSLVSSATGRCSISETLQIDSLTGVVSVKNSECLDREVNDEIEAFIAAKDGGGLSTSVKLRVRLMDINDNDPIIQISESLGVSENFPPGVVVGKIRCSDLDSGSNAKILLELSENNTLQVRSAFDIIPEGENLGNLFASRANVRGMSDVTGLLITKRTLDREDVETYNINLVARDLGEPQRVTRKTVQVIVLDENDNSPTLRFPQPNTTVGYHP--QVYANSPHGSKVCVLRSHDPDRGENGTVIYALQQDTNGSRFFQLEQSTGKLTTAW 807
BLAST of Protocadherin alpha-2 vs. TrEMBL
Match: W6USR7 (Protocadherin-1 OS=Echinococcus granulosus OX=6210 GN=EGR_00615 PE=4 SV=1) HSP 1 Score: 352.829 bits (904), Expect = 1.043e-99 Identity = 253/789 (32.07%), Postives = 389/789 (49.30%), Query Frame = 2
Query: 146 TARFTIPDNNARHSSVGNIISKLPSRFPRGSY---QIITRRSSFTKFNQYFRISDSGEIRITKVFDRDDVNNVCGPLGCCDKPSCEIVLDIIVTV-------IPKNERIPVKVVIVIEDENDNAP----DXXXXXXXXXXXXNDATQLDHNLPKALDKDCPIYGIKNYSLSGNK--VEYFSLK--------------IRQFQPFLSVKKSFDFENPSEKQFNLSLNAIDNGGKSATLQLIVNVI--DINDNPPIFQKK-IVNVTIQENTTF-PDAILKLNATDLDSGNNAQISYKFSSINRPIIRETFQLQSETGKIYLLKTLDYELYSEQNFDINVLAIDHGSPQLSDSCIIKVNVTDINDNSPVIEIVHSQPIPENEQITDPALKLYVSDYDSID-NDVKCQAE------KIGRRLKLEQVEKSSYFIYATEIYDYEKEKNLSLSILCQDSGKEPRYTKQLL---TIFIKDVNDNRPKFLRSFYRKSINEDQEKLKPFTKVQALDKDSDDFGKVKYSI------GLKDRKYFSIDEISGEVRLANE--IDRETKDFYNVSVIATDGGGLKDYSYIEISILDVNDNYPKLKSGSSMRVNENLPVGSVVGYISVIDLDLGDNSKVEW------------TYD-----------FL--GNSSSMLQIENCTVYTSTVLDRESIEHLHILITMVDMGYPRLTSSATITVSVIDENDNIPKVIYPKTGSLVEEREMDHIAVNSPKYTTVLSIKSFDPDLGINGDVLYHILP-SNGSQYFIINQTSGVLKTTW 2278
+A F + D +VGNI L +P+ S I+ S F +FN+YF I+ +G I K DRD+VN++CGPL CC C I ++ V + ++++ + I + D NDN+P + + A LP A+D D G+ Y + N + F L R P L + D+ENP++K+F L + AID G S T L V V+ DINDN P+F + I N+ + ENTT+ PD + + ATD+DS +N I+Y S +N P + E F + +G +YL LDYE+YSE+ F + V+A D+G+P+ S + + V D+NDN P + + + + E T P ++ YV D DS+ V C+ L+L++V ++YF++ I+DYE+ ++ S+ I+C DS +P T++ + T+ I D ND+ P+F + + E K K T+V A D D+ ++ YS+ ++ FSID ++G V + + +DRE + A DGGGL + I + D+NDN P ++ S+ V ENLP G VVG + D D+G NS++ +D FL G M I V T LDRE IE I D G P+ T+ ++ V V+DENDN+P + +P + V + NSP + V ++S+DPD G NG V+Y + +NGS+YF ++Q +G L T W
Sbjct: 83 SATFQMVDEIKPGQTVGNICHAL---WPKSSIVFSLIVVTSSRFQRFNEYFSITKNGSIVAQKFVDRDNVNDICGPLDCCQSAICIIHARVMFIVEQSENSMMHSHDQVLAHLQIHLADINDNSPQFPLNSQGYPHFTIRVQEGAKFAREMLPSAVDLDSAGNGVVQYRIKANSPSADLFQLTYEKVLINPLSESHGWRLSPPTLIQLRELDYENPADKEFELIVIAIDGGEPSLTGSLSVTVVLMDINDNTPVFDRTNISNIELAENTTYSPDPVYRFLATDMDSVDNGLITYSLSPLNEPKVFEKFSIDGRSGALYLNSILDYEVYSERRFTVIVVASDNGTPKRSGTTTLTVVTKDVNDNLPSLVVQENITVIEGLNYTKPVVRFYVKDDDSVSRGKVICRPAPNRVKGAGSASLRLQEVTTNAYFVFTEGIFDYEEAQSASVEIVCSDSA-DPFDTRERILRITLAIGDANDHYPEFGVTELLAKLPEHSPKGKRVTQVTANDADAGIHARLTYSLINSSGRRCSVQEIFSIDSMTGVVTVKDSECLDREVNEEIEAFAAAEDGGGLSTSVKLRIRLTDINDNSPSIQVLDSLSVAENLPAGVVVGRVRCTDADIGPNSEIRLELAANNTQQVRNAFDTIRERGSARNLFLSHGMVRGMNDITGLLV-TKKPLDREDIESYTIHFVATDSGNPQRTTYKSVQVLVLDENDNVPALRFPHPDTTVGYHP--QVYTNSPHGSKVCVLRSYDPDKGENGTVIYTLQQNTNGSRYFQLDQATGELTTAW 864
BLAST of Protocadherin alpha-2 vs. Ensembl Cavefish
Match: pcdh11 (protocadherin 11 [Source:ZFIN;Acc:ZDB-GENE-140106-21]) HSP 1 Score: 239.965 bits (611), Expect = 7.634e-65 Identity = 217/698 (31.09%), Postives = 341/698 (48.85%), Query Frame = 2
Query: 254 RRSSFTKFNQYFRISDSGEIRIT----KVF---DRDDVNNVCGPLGCCDKPSCEIVLDIIVTVIPKNERIPVKVVIVIEDENDNAPDXXXXXXXXXXXXNDATQLDHNLPKALDKDCPIYGIKNYSLSGNKVEYFSLKIRQFQ-----PFLSVKKSFDFENPSEKQFNLSLNAIDNGG--KSATLQLIVNVIDINDNPPIFQKKIVNVTIQENTTFPDAILKLNATDLDSGNNAQISYKFSSINRPIIRETFQLQSETGKIYLLKTLDYELYSEQNFDINVLAIDHGSPQLSDSCIIKVNVTDINDNSPVIE-----------IVHSQPIPENEQITDPALKLYVSDYDS-IDNDVKCQAEKIGRRLKLEQVEKSSYFIYATEIYDYEKEKNLSLSILCQDSGKEPRYTKQLLTIFIKDVNDNRPKFLRSFYRKSINEDQEKLKPFTKVQALDKDSDDFGKVKYSIGLKDRKYFSIDEISGEVRLANEIDRETKDFYNVSVIATDGGG--LKDYSYIEISILDVNDNYPKLKSGS-SMRVNENLPVGSVVGYISVIDLDLGDNSKVEWTYDFLGNSSSMLQIENCTVYTSTVLDRESIEHLHILITMVDMGYPRLTSSATITVSVIDENDNIPKVIYPKTGSLVEEREMDHIAVNSPKYTTVLSIKSFDPDLGINGDVLYHILPSNGSQYFIINQTSG 2260
+ SS +F ++ D +R+ ++F +R D +C G ++ C +I V V+P VK+ +IED NDNAP F + ISI EN A + +P A D D I GI++Y L V F L I + P L V+++ D E ++ F + + D G KS+T L V V D+NDN P+F+ V V + EN ++ +L+ATD D G+NAQI + FS+ P + F + S TG I + + LD E S + VLA D GS S + +I VNVTD+NDN P I+ ++ S+ P N +I AL + V+D D+ ++ V C + +L+ V + + DYE + ++ I+ DSGK P T ++ I IKD NDN P F + + SI E+ + K+ A D DS + YS+G F+ID SG + ++ +DRE ++ Y+ +VIA D G L+ +++ + D NDN P + V ENLP+ VG I+V D D GDN+ V + G + ++ + + + DRE ++ VD G + TS A +T++V+D NDN P + P + D + + + V + + D D G+N ++ Y I+ + F I++T+G
Sbjct: 96 KLSSALQFKPVYKTGDVPLVRVEASTGEIFTTANRIDRERLCS--GVFNEKRC--FYEIEVAVLPDEIFRLVKIRFLIEDINDNAPLFQSTVINISIPENTAINNRYPVPSAFDPDVGINGIQHYELV-KSVSEFGLDIIETPEGDKWPQLIVQQNLDRE--TKDTFVMKIKVEDGGNPPKSSTAILQVTVSDVNDNRPVFKDSEVEVNVPENAPMGTSVTQLHATDADLGSNAQIHFSFSNQISPATKRHFAIDSSTGLITVKQPLDRE--SNPVHKLIVLASD-GSATPSRATVI-VNVTDVNDNVPSIDTRYIMNPVNGTVLLSENAPLNTKI---AL-ITVTDRDADLNGKVTCYTDH-DVPFRLKPVFNDQFLLETAAPLDYETTREYAIKIVASDSGKPPLNTSAMVLIKIKDENDNAPVFPQPEIQLSIPENNDPGTQLIKITATDADSGSNALIIYSLGPDAPDGFNIDPRSGILSVSKRLDREKQEKYSFTVIARDNGSNPLQSNVTVKLIVQDQNDNSPAFTHAEYNFYVPENLPLYGTVGLITVTDADAGDNAIVTLSI-INGKDNFIIDPKTGVIKPNITFDREQQSSYTFVVKAVDSGLIQTTSYAKVTINVVDVNDNRPVFVIPSSN-----YSYDLVPFTTNPGSVVTRVFAIDNDTGMNAELQYSIIGGSPRGLFAIDKTTG 771 HSP 2 Score: 119.783 bits (299), Expect = 6.694e-27 Identity = 138/522 (26.44%), Postives = 228/522 (43.68%), Query Frame = 2
Query: 788 DINDNPPIFQKKIVNVTIQENTTFPDAILKLNATDLDSGNNAQISYKF----SSINRPIIRETFQLQSETGKIYLLKTLDYELYSEQNFDINVLAIDHGSPQLSDSCIIKVNVTDINDNSPVIEIVHSQP-IPENEQITDPALKLYVSDYDSIDNDVKCQ---AEKIGRRLKLE-QVEKSSYFIYATEIYDYEKEKNLSLSILCQDSGKEPRYTKQLLTIFIKDVNDNRPKFLRSFYRKSIN------EDQEKLKPFTKVQALDKDSDDFGKVK----YSIGLKDRKYFSIDEISGEVRLANEIDRETKDFYNVSVIATDGGG--LKDYSYIEISILDVNDNYPKLKSGS-SMRVNENLPVGSVVGYISVIDLDLGDNSKVEWTYDFLGNSSSMLQIENCTVYTSTVLDRESIEHLHILITMVDMGYPRLTSSATITVSVIDENDNIPKVIYPKTGSLVEEREMDHIAVNSPKYTTVLSIKSFDPDLGINGDVLYHILPSNGSQYFIINQTSGVLKTTWIYD 2287
DINDN P+FQ ++N++I ENT + +A D D G N Y+ S II ET + + ++ + + LD E ++ F + + D G+P S + I++V V+D+NDN PV + + +PEN + +L+ +D D + ++ + + +I K ++ S+ I + D E L +L D P ++ + + + DVNDN P + +N E+ + D+D+D GKV + + + + F+ D+ E A +D ET Y + ++A+D G L + + I I D NDN P + + EN G+ + I+ D D G N+ + ++ + + + S LDRE E + D G L S+ T+ + V D+NDN P + + V E N P Y TV I D D G N V I+ NG FII+ +GV+K +D
Sbjct: 171 DINDNAPLFQSTVINISIPENTAINNRYPVPSAFDPDVGINGIQHYELVKSVSEFGLDII-ETPE-GDKWPQLIVQQNLDRE--TKDTFVMKIKVEDGGNPPKSSTAILQVTVSDVNDNRPVFKDSEVEVNVPENAPMGTSVTQLHATDAD-LGSNAQIHFSFSNQISPATKRHFAIDSSTGLITVKQPLDRESNPVHKLIVLASDGSATP--SRATVIVNVTDVNDNVPSIDTRYIMNPVNGTVLLSENAPLNTKIALITVTDRDADLNGKVTCYTDHDVPFRLKPVFN-DQFLLET--AAPLDYETTREYAIKIVASDSGKPPLNTSAMVLIKIKDENDNAPVFPQPEIQLSIPENNDPGTQLIKITATDADSGSNALIIYSLGPDAPDGFNIDPRSGILSVSKRLDREKQEKYSFTVIARDNGSNPLQSNVTVKLIVQDQNDNSPAFTHAEYNFYVPE--------NLPLYGTVGLITVTDADAGDNAIVTLSII--NGKDNFIIDPKTGVIKPNITFD 672
BLAST of Protocadherin alpha-2 vs. Ensembl Cavefish
Match: pcdh11 (protocadherin 11 [Source:ZFIN;Acc:ZDB-GENE-140106-21]) HSP 1 Score: 239.58 bits (610), Expect = 2.707e-64 Identity = 216/698 (30.95%), Postives = 340/698 (48.71%), Query Frame = 2
Query: 254 RRSSFTKFNQYFRISDSGEIRIT----KVF---DRDDVNNVCGPLGCCDKPSCEIVLDIIVTVIPKNERIPVKVVIVIEDENDNAPDXXXXXXXXXXXXNDATQLDHNLPKALDKDCPIYGIKNYSLSGNKVEYFSLKIRQFQ-----PFLSVKKSFDFENPSEKQFNLSLNAIDNGG--KSATLQLIVNVIDINDNPPIFQKKIVNVTIQENTTFPDAILKLNATDLDSGNNAQISYKFSSINRPIIRETFQLQSETGKIYLLKTLDYELYSEQNFDINVLAIDHGSPQLSDSCIIKVNVTDINDNSPVIE-----------IVHSQPIPENEQITDPALKLYVSDYDS-IDNDVKCQAEKIGRRLKLEQVEKSSYFIYATEIYDYEKEKNLSLSILCQDSGKEPRYTKQLLTIFIKDVNDNRPKFLRSFYRKSINEDQEKLKPFTKVQALDKDSDDFGKVKYSIGLKDRKYFSIDEISGEVRLANEIDRETKDFYNVSVIATDGGG--LKDYSYIEISILDVNDNYPKLKSGS-SMRVNENLPVGSVVGYISVIDLDLGDNSKVEWTYDFLGNSSSMLQIENCTVYTSTVLDRESIEHLHILITMVDMGYPRLTSSATITVSVIDENDNIPKVIYPKTGSLVEEREMDHIAVNSPKYTTVLSIKSFDPDLGINGDVLYHILPSNGSQYFIINQTSG 2260
+ SS +F ++ D +R+ ++F +R D +C G ++ C +I V V+P VK+ +IED NDNAP F + ISI EN A + +P A D D I GI++Y L F L I + P L V+++ D E ++ F + + D G KS+T L V V D+NDN P+F+ V V + EN ++ +L+ATD D G+NAQI + FS+ P + F + S TG I + + LD E S + VLA D GS S + +I VNVTD+NDN P I+ ++ S+ P N +I AL + V+D D+ ++ V C + +L+ V + + DYE + ++ I+ DSGK P T ++ I IKD NDN P F + + SI E+ + K+ A D DS + YS+G F+ID SG + ++ +DRE ++ Y+ +VIA D G L+ +++ + D NDN P + V ENLP+ VG I+V D D GDN+ V + G + ++ + + + DRE ++ VD G + TS A +T++V+D NDN P + P + D + + + V + + D D G+N ++ Y I+ + F I++T+G
Sbjct: 56 KLSSALQFKPVYKTGDVPLVRVEASTGEIFTTANRIDRERLCS--GVFNEKRC--FYEIEVAVLPDEIFRLVKIRFLIEDINDNAPLFQSTVINISIPENTAINNRYPVPSAFDPDVGINGIQHYELVKVGALEFGLDIIETPEGDKWPQLIVQQNLDRE--TKDTFVMKIKVEDGGNPPKSSTAILQVTVSDVNDNRPVFKDSEVEVNVPENAPMGTSVTQLHATDADLGSNAQIHFSFSNQISPATKRHFAIDSSTGLITVKQPLDRE--SNPVHKLIVLASD-GSATPSRATVI-VNVTDVNDNVPSIDTRYIMNPVNGTVLLSENAPLNTKI---AL-ITVTDRDADLNGKVTCYTDH-DVPFRLKPVFNDQFLLETAAPLDYETTREYAIKIVASDSGKPPLNTSAMVLIKIKDENDNAPVFPQPEIQLSIPENNDPGTQLIKITATDADSGSNALIIYSLGPDAPDGFNIDPRSGILSVSKRLDREKQEKYSFTVIARDNGSNPLQSNVTVKLIVQDQNDNSPAFTHAEYNFYVPENLPLYGTVGLITVTDADAGDNAIVTLSI-INGKDNFIIDPKTGVIKPNITFDREQQSSYTFVVKAVDSGLIQTTSYAKVTINVVDVNDNRPVFVIPSSN-----YSYDLVPFTTNPGSVVTRVFAIDNDTGMNAELQYSIIGGSPRGLFAIDKTTG 732 HSP 2 Score: 118.242 bits (295), Expect = 2.410e-26 Identity = 136/522 (26.05%), Postives = 227/522 (43.49%), Query Frame = 2
Query: 788 DINDNPPIFQKKIVNVTIQENTTFPDAILKLNATDLDSGNNAQISYKFSSINRPI----IRETFQLQSETGKIYLLKTLDYELYSEQNFDINVLAIDHGSPQLSDSCIIKVNVTDINDNSPVIEIVHSQP-IPENEQITDPALKLYVSDYDSIDNDVKCQ---AEKIGRRLKLE-QVEKSSYFIYATEIYDYEKEKNLSLSILCQDSGKEPRYTKQLLTIFIKDVNDNRPKFLRSFYRKSIN------EDQEKLKPFTKVQALDKDSDDFGKVK----YSIGLKDRKYFSIDEISGEVRLANEIDRETKDFYNVSVIATDGGG--LKDYSYIEISILDVNDNYPKLKSGS-SMRVNENLPVGSVVGYISVIDLDLGDNSKVEWTYDFLGNSSSMLQIENCTVYTSTVLDRESIEHLHILITMVDMGYPRLTSSATITVSVIDENDNIPKVIYPKTGSLVEEREMDHIAVNSPKYTTVLSIKSFDPDLGINGDVLYHILPSNGSQYFIINQTSGVLKTTWIYD 2287
DINDN P+FQ ++N++I ENT + +A D D G N Y+ + I ET + + ++ + + LD E ++ F + + D G+P S + I++V V+D+NDN PV + + +PEN + +L+ +D D + ++ + + +I K ++ S+ I + D E L +L D P ++ + + + DVNDN P + +N E+ + D+D+D GKV + + + + F+ D+ E A +D ET Y + ++A+D G L + + I I D NDN P + + EN G+ + I+ D D G N+ + ++ + + + S LDRE E + D G L S+ T+ + V D+NDN P + + V E N P Y TV I D D G N V I+ NG FII+ +GV+K +D
Sbjct: 131 DINDNAPLFQSTVINISIPENTAINNRYPVPSAFDPDVGINGIQHYELVKVGALEFGLDIIETPE-GDKWPQLIVQQNLDRE--TKDTFVMKIKVEDGGNPPKSSTAILQVTVSDVNDNRPVFKDSEVEVNVPENAPMGTSVTQLHATDAD-LGSNAQIHFSFSNQISPATKRHFAIDSSTGLITVKQPLDRESNPVHKLIVLASDGSATP--SRATVIVNVTDVNDNVPSIDTRYIMNPVNGTVLLSENAPLNTKIALITVTDRDADLNGKVTCYTDHDVPFRLKPVFN-DQFLLET--AAPLDYETTREYAIKIVASDSGKPPLNTSAMVLIKIKDENDNAPVFPQPEIQLSIPENNDPGTQLIKITATDADSGSNALIIYSLGPDAPDGFNIDPRSGILSVSKRLDREKQEKYSFTVIARDNGSNPLQSNVTVKLIVQDQNDNSPAFTHAEYNFYVPE--------NLPLYGTVGLITVTDADAGDNAIVTLSII--NGKDNFIIDPKTGVIKPNITFD 633
BLAST of Protocadherin alpha-2 vs. Ensembl Cavefish
Match: pcdh11 (protocadherin 11 [Source:ZFIN;Acc:ZDB-GENE-140106-21]) HSP 1 Score: 239.195 bits (609), Expect = 3.436e-64 Identity = 219/700 (31.29%), Postives = 340/700 (48.57%), Query Frame = 2
Query: 254 RRSSFTKFNQYFRISD---------SGEIRITKVFDRDDVNNVCGPLGCCDKPSCEIVLDIIVTVIPKNERIPVKVVIVIEDENDNAPDXXXXXXXXXXXXNDATQLDHNLPKALDKDCPIYGIKNYSLSGNKVEYFSLKIRQFQ-----PFLSVKKSFDFENPSEKQFNLSLNAIDNGG--KSATLQLIVNVIDINDNPPIFQKKIVNVTIQENTTFPDAILKLNATDLDSGNNAQISYKFSSINRPIIRETFQLQSETGKIYLLKTLDYELYSEQNFDINVLAIDHGSPQLSDSCIIKVNVTDINDNSPVIE-----------IVHSQPIPENEQITDPALKLYVSDYDS-IDNDVKCQAEKIGRRLKLEQVEKSSYFIYATEIYDYEKEKNLSLSILCQDSGKEPRYTKQLLTIFIKDVNDNRPKFLRSFYRKSINEDQEKLKPFTKVQALDKDSDDFGKVKYSIGLKDRKYFSIDEISGEVRLANEIDRETKDFYNVSVIATDGGG--LKDYSYIEISILDVNDNYPKLKSGS-SMRVNENLPVGSVVGYISVIDLDLGDNSKVEWTYDFLGNSSSMLQIENCTVYTSTVLDRESIEHLHILITMVDMGYPRLTSSATITVSVIDENDNIPKVIYPKTGSLVEEREMDHIAVNSPKYTTVLSIKSFDPDLGINGDVLYHILPSNGSQYFIINQTSG 2260
+ SS +F ++ D +GEI T +R D +C G ++ C +I V V+P VK+ +IED NDNAP F + ISI EN A + +P A D D I GI++Y L V F L I + P L V+++ D E ++ F + + D G KS+T L V V D+NDN P+F+ V V + EN ++ +L+ATD D G+NAQI + FS+ P + F + S TG I + + LD E S + VLA D GS S + +I VNVTD+NDN P I+ ++ S+ P N +I AL + V+D D+ ++ V C + +L+ V + + DYE + ++ I+ DSGK P T ++ I IKD NDN P F + + SI E+ + K+ A D DS + YS+G F+ID SG + ++ +DRE ++ Y+ +VIA D G L+ +++ + D NDN P + V ENLP+ VG I+V D D GDN+ V + G + ++ + + + DRE ++ VD G + TS A +T++V+D NDN P + P + D + + + V + + D D G+N ++ Y I+ + F I++T+G
Sbjct: 96 KLSSALQFKPVYKTGDVPLVRVEASTGEIFTTA--NRIDRERLCS--GVFNEKRC--FYEIEVAVLPDEIFRLVKIRFLIEDINDNAPLFQSTVINISIPENTAINNRYPVPSAFDPDVGINGIQHYELV-KSVSEFGLDIIETPEGDKWPQLIVQQNLDRE--TKDTFVMKIKVEDGGNPPKSSTAILQVTVSDVNDNRPVFKDSEVEVNVPENAPMGTSVTQLHATDADLGSNAQIHFSFSNQISPATKRHFAIDSSTGLITVKQPLDRE--SNPVHKLIVLASD-GSATPSRATVI-VNVTDVNDNVPSIDTRYIMNPVNGTVLLSENAPLNTKI---AL-ITVTDRDADLNGKVTCYTDH-DVPFRLKPVFNDQFLLETAAPLDYETTREYAIKIVASDSGKPPLNTSAMVLIKIKDENDNAPVFPQPEIQLSIPENNDPGTQLIKITATDADSGSNALIIYSLGPDAPDGFNIDPRSGILSVSKRLDREKQEKYSFTVIARDNGSNPLQSNVTVKLIVQDQNDNSPAFTHAEYNFYVPENLPLYGTVGLITVTDADAGDNAIVTLSI-INGKDNFIIDPKTGVIKPNITFDREQQSSYTFVVKAVDSGLIQTTSYAKVTINVVDVNDNRPVFVIPSSN-----YSYDLVPFTTNPGSVVTRVFAIDNDTGMNAELQYSIIGGSPRGLFAIDKTTG 771 HSP 2 Score: 119.398 bits (298), Expect = 1.031e-26 Identity = 138/522 (26.44%), Postives = 228/522 (43.68%), Query Frame = 2
Query: 788 DINDNPPIFQKKIVNVTIQENTTFPDAILKLNATDLDSGNNAQISYKF----SSINRPIIRETFQLQSETGKIYLLKTLDYELYSEQNFDINVLAIDHGSPQLSDSCIIKVNVTDINDNSPVIEIVHSQP-IPENEQITDPALKLYVSDYDSIDNDVKCQ---AEKIGRRLKLE-QVEKSSYFIYATEIYDYEKEKNLSLSILCQDSGKEPRYTKQLLTIFIKDVNDNRPKFLRSFYRKSIN------EDQEKLKPFTKVQALDKDSDDFGKVK----YSIGLKDRKYFSIDEISGEVRLANEIDRETKDFYNVSVIATDGGG--LKDYSYIEISILDVNDNYPKLKSGS-SMRVNENLPVGSVVGYISVIDLDLGDNSKVEWTYDFLGNSSSMLQIENCTVYTSTVLDRESIEHLHILITMVDMGYPRLTSSATITVSVIDENDNIPKVIYPKTGSLVEEREMDHIAVNSPKYTTVLSIKSFDPDLGINGDVLYHILPSNGSQYFIINQTSGVLKTTWIYD 2287
DINDN P+FQ ++N++I ENT + +A D D G N Y+ S II ET + + ++ + + LD E ++ F + + D G+P S + I++V V+D+NDN PV + + +PEN + +L+ +D D + ++ + + +I K ++ S+ I + D E L +L D P ++ + + + DVNDN P + +N E+ + D+D+D GKV + + + + F+ D+ E A +D ET Y + ++A+D G L + + I I D NDN P + + EN G+ + I+ D D G N+ + ++ + + + S LDRE E + D G L S+ T+ + V D+NDN P + + V E N P Y TV I D D G N V I+ NG FII+ +GV+K +D
Sbjct: 171 DINDNAPLFQSTVINISIPENTAINNRYPVPSAFDPDVGINGIQHYELVKSVSEFGLDII-ETPE-GDKWPQLIVQQNLDRE--TKDTFVMKIKVEDGGNPPKSSTAILQVTVSDVNDNRPVFKDSEVEVNVPENAPMGTSVTQLHATDAD-LGSNAQIHFSFSNQISPATKRHFAIDSSTGLITVKQPLDRESNPVHKLIVLASDGSATP--SRATVIVNVTDVNDNVPSIDTRYIMNPVNGTVLLSENAPLNTKIALITVTDRDADLNGKVTCYTDHDVPFRLKPVFN-DQFLLET--AAPLDYETTREYAIKIVASDSGKPPLNTSAMVLIKIKDENDNAPVFPQPEIQLSIPENNDPGTQLIKITATDADSGSNALIIYSLGPDAPDGFNIDPRSGILSVSKRLDREKQEKYSFTVIARDNGSNPLQSNVTVKLIVQDQNDNSPAFTHAEYNFYVPE--------NLPLYGTVGLITVTDADAGDNAIVTLSII--NGKDNFIIDPKTGVIKPNITFD 672
BLAST of Protocadherin alpha-2 vs. Ensembl Cavefish
Match: pcdh9 (protocadherin 9 [Source:ZFIN;Acc:ZDB-GENE-091015-1]) HSP 1 Score: 234.958 bits (598), Expect = 2.676e-63 Identity = 214/701 (30.53%), Postives = 340/701 (48.50%), Query Frame = 2
Query: 233 GSYQIITRRSSFTKFNQYFRI-SDSGEIRITKVFDRDDVNNVC-GPLGCCDKPSCEIVLDIIVTVIPKNERIPVKVVIVIEDENDNAPDXXXXXXXXXXXXNDATQLDHNLPKALDKDCPIYGIKNYSLSGNKVEYFSLKIRQFQ-----PFLSVKKSFDFENPSEKQFNLSLNAIDNGG---KSATLQLIVNVIDINDNPPIFQKKIVNVTIQENTTFPDAILKLNATDLDSGNNAQISYKFSSINRPIIRETFQLQSETGKIYLLKTLDYELYSEQNFDINVLAIDHGSPQLSDSCIIKVNVTDINDNSPVIE-----------IVHSQPIPENEQITDPALKLYVSDYDS-IDNDVKCQAEKIGRRLKLEQVEKSSYFIYATEIYDYEKEKNLSLSILCQDSGKEPRYTKQLLTIFIKDVNDNRPKFLRSFYRKSINEDQEKLKPFTKVQALDKDSDDFGKVKYSIGLKDRKYFSIDEISGEVRLANEIDRETKDFYNVSVIATDGG--GLKDYSYIEISILDVNDNYPKLKSGS-SMRVNENLPVGSVVGYISVIDLDLGDNSKVEWTYDFLGNSSSMLQIENCTVYTSTVLDRESIEHLHILITMVDMGYPRLTSSATITVSVIDENDNIPKVIYPKTGSLVEEREMDHIAVNSPKYTTVLSIKSFDPDLGINGDVLYHILPSNGSQYFIINQTSG 2260
S ++ R S N R+ S++GEI T +R D +C GP E +I V ++P + +K+ IV++D NDNAP F ISI EN +P A D D + Y L N F L I + P L V+++ D E +K + +++GG KS+T L V V D+NDN P+F++ + V I E++ ++++L ATD D G NA+I Y F + P R F L S TG I + + LD E N ++VLA D S S + +NVTD+NDN+P I+ ++ S+ P N +I AL + VSD D+ ++ V C EK L+ V + Y + + + DYE K I+ DSGK L+ + ++D NDN P F + +++E+ ++ T + A D+DS ++ Y +G + +F +D +G + + DRE ++ + +V A D G L+ + + ++ILD NDN PK V+ENLP S VG I+V D D G+N+ V + N + +L + ++ DRE + VD G+P +S+A +T++VID NDN P VIYP + + + +++ + V + + D D G+N ++ Y I+ N F I+ +G
Sbjct: 58 ASNNLVYRLVSKAGDNPLLRVMSNTGEIFTTS--NRIDREKLCPGP----SYEDSECSFEIEVVILPNDYFRLIKIKIVVKDTNDNAPMFPSPVINISIPENTLINSRFAIPSATDPDMGPNSVYKYELV-NGQSAFGLDIVETPEGEKWPQLIVQQNLDRE---QKDTYVMKIKVEDGGSPQKSSTAILQVTVTDVNDNRPVFKESQIEVHIPESSPVGTSVVQLQATDADVGANAEIKYMFGTQVSPATRRLFALNSTTGLITVQRPLDRE--ETANHKLSVLASDGSSS--SARATVTINVTDVNDNAPNIDLRYIISPTNGTVLLSEKDPVNTKI---AL-ITVSDKDTDVNGKVICFIEK-DVPFHLKAVYDNQYLLETSALLDYEGTKEYIFKIVASDSGKPSLNQTALVRVRLEDENDNPPIFTQPVIELTVSENNKRDLYLTTITATDEDSGRNAEIVYQLG-PNASFFDLDRKTGVLTASRVFDREDQERFLFTVTARDNGTRALQSQAAVIVTILDQNDNSPKFTHNHFQFFVSENLPKYSTVGVITVTDADAGENAVVSLSI-LNDNENFILDPYTGVIKSNVSFDREQQSSYTFDVRAVDSGHPPCSSAAKVTINVIDVNDNPPIVIYPPSNT-----SFKLVPLSAIPGSVVAEVFAVDGDTGMNAELKYTIVNGNNKGLFRIDPVTG 732 HSP 2 Score: 129.413 bits (324), Expect = 7.613e-30 Identity = 121/471 (25.69%), Postives = 220/471 (46.71%), Query Frame = 2
Query: 665 FLSVKKSFDFENPSEKQFNLSLNAIDNGGKSATLQLIVNVIDINDNPPIFQKKIV------NVTIQENTTFPDAILKLNATDLDSGNNAQISYKFSSINRPIIRETFQLQSETGKIYLLKT---LDYELYSEQNFDINVLAIDHGSPQLSDSCIIKVNVTDINDNSPVIEIVHSQPIPENEQITDPALKLYVSDYDSIDNDVKCQAE---KIGRRLKLEQVEKSSYFIYATEIYDYEKEKNLSLSILCQDSGKEPRYTKQLLTIFIKDVNDNRPKFLRSFYRKSINEDQEKLKPFTKVQALDKDSDDFGKVKYSIGLKDRKYFSIDEISGEVRLANEIDRETKDFYNVSVIATDGGG--LKDYSYIEISILDVNDN-----YPKLKSGSSMRVNENLPVGSVVGYISVIDLDLGDNSKVEWTYDFLGNSSSMLQIENCTVYTSTVLDRESIEH---LH-ILITMVDMGYPR 2008
++V++ D E + + LS+ A D SA + +NV D+NDN P + + V + E I + +D D+ N ++ F + P F L++ YLL+T LDYE E F I +A D G P L+ + +++V + D NDN P+ +QP+ E + LY++ + D D AE ++G +++ + + A+ ++D E ++ ++ +D+G ++ + + I D NDN PKF + ++ ++E+ K + D D+ + V SI L D + F +D +G ++ DRE + Y V A D G + + I+++DVNDN YP + + +P GSVV + +D D G N+++++T GN+ + +I+ T + L+ + E LH +++ + D+GYP+
Sbjct: 310 LITVQRPLDREETANHK--LSVLASDGSSSSARATVTINVTDVNDNAPNIDLRYIISPTNGTVLLSEKDPVNTKIALITVSDKDTDVNGKV-ICFIEKDVP-----FHLKAVYDNQYLLETSALLDYEGTKEYIFKI--VASDSGKPSLNQTALVRVRLEDENDNPPIF----TQPVIELTVSENNKRDLYLTTITATDEDSGRNAEIVYQLGPNASFFDLDRKTGVLTASRVFDREDQERFLFTVTARDNGTRALQSQAAVIVTILDQNDNSPKFTHNHFQFFVSENLPKYSTVGVITVTDADAGENAVVSLSI-LNDNENFILDPYTGVIKSNVSFDREQQSSYTFDVRAVDSGHPPCSSAAKVTINVIDVNDNPPIVIYPPSNTSFKLVPLSAIP-GSVVAEVFAVDGDTGMNAELKYTI-VNGNNKGLFRIDPVT--GNITLEEKPTEADSGLHRLVVNISDLGYPK 761
BLAST of Protocadherin alpha-2 vs. Ensembl Cavefish
Match: pcdh9 (protocadherin 9 [Source:ZFIN;Acc:ZDB-GENE-091015-1]) HSP 1 Score: 235.343 bits (599), Expect = 2.749e-63 Identity = 214/701 (30.53%), Postives = 340/701 (48.50%), Query Frame = 2
Query: 233 GSYQIITRRSSFTKFNQYFRI-SDSGEIRITKVFDRDDVNNVC-GPLGCCDKPSCEIVLDIIVTVIPKNERIPVKVVIVIEDENDNAPDXXXXXXXXXXXXNDATQLDHNLPKALDKDCPIYGIKNYSLSGNKVEYFSLKIRQFQ-----PFLSVKKSFDFENPSEKQFNLSLNAIDNGG---KSATLQLIVNVIDINDNPPIFQKKIVNVTIQENTTFPDAILKLNATDLDSGNNAQISYKFSSINRPIIRETFQLQSETGKIYLLKTLDYELYSEQNFDINVLAIDHGSPQLSDSCIIKVNVTDINDNSPVIE-----------IVHSQPIPENEQITDPALKLYVSDYDS-IDNDVKCQAEKIGRRLKLEQVEKSSYFIYATEIYDYEKEKNLSLSILCQDSGKEPRYTKQLLTIFIKDVNDNRPKFLRSFYRKSINEDQEKLKPFTKVQALDKDSDDFGKVKYSIGLKDRKYFSIDEISGEVRLANEIDRETKDFYNVSVIATDGG--GLKDYSYIEISILDVNDNYPKLKSGS-SMRVNENLPVGSVVGYISVIDLDLGDNSKVEWTYDFLGNSSSMLQIENCTVYTSTVLDRESIEHLHILITMVDMGYPRLTSSATITVSVIDENDNIPKVIYPKTGSLVEEREMDHIAVNSPKYTTVLSIKSFDPDLGINGDVLYHILPSNGSQYFIINQTSG 2260
S ++ R S N R+ S++GEI T +R D +C GP E +I V ++P + +K+ IV++D NDNAP F ISI EN +P A D D + Y L N F L I + P L V+++ D E +K + +++GG KS+T L V V D+NDN P+F++ + V I E++ ++++L ATD D G NA+I Y F + P R F L S TG I + + LD E N ++VLA D S S + +NVTD+NDN+P I+ ++ S+ P N +I AL + VSD D+ ++ V C EK L+ V + Y + + + DYE K I+ DSGK L+ + ++D NDN P F + +++E+ ++ T + A D+DS ++ Y +G + +F +D +G + + DRE ++ + +V A D G L+ + + ++ILD NDN PK V+ENLP S VG I+V D D G+N+ V + N + +L + ++ DRE + VD G+P +S+A +T++VID NDN P VIYP + + + +++ + V + + D D G+N ++ Y I+ N F I+ +G
Sbjct: 58 ASNNLVYRLVSKAGDNPLLRVMSNTGEIFTTS--NRIDREKLCPGP----SYEDSECSFEIEVVILPNDYFRLIKIKIVVKDTNDNAPMFPSPVINISIPENTLINSRFAIPSATDPDMGPNSVYKYELV-NGQSAFGLDIVETPEGEKWPQLIVQQNLDRE---QKDTYVMKIKVEDGGSPQKSSTAILQVTVTDVNDNRPVFKESQIEVHIPESSPVGTSVVQLQATDADVGANAEIKYMFGTQVSPATRRLFALNSTTGLITVQRPLDRE--ETANHKLSVLASDGSSS--SARATVTINVTDVNDNAPNIDLRYIISPTNGTVLLSEKDPVNTKI---AL-ITVSDKDTDVNGKVICFIEK-DVPFHLKAVYDNQYLLETSALLDYEGTKEYIFKIVASDSGKPSLNQTALVRVRLEDENDNPPIFTQPVIELTVSENNKRDLYLTTITATDEDSGRNAEIVYQLG-PNASFFDLDRKTGVLTASRVFDREDQERFLFTVTARDNGTRALQSQAAVIVTILDQNDNSPKFTHNHFQFFVSENLPKYSTVGVITVTDADAGENAVVSLSI-LNDNENFILDPYTGVIKSNVSFDREQQSSYTFDVRAVDSGHPPCSSAAKVTINVIDVNDNPPIVIYPPSNT-----SFKLVPLSAIPGSVVAEVFAVDGDTGMNAELKYTIVNGNNKGLFRIDPVTG 732 HSP 2 Score: 129.028 bits (323), Expect = 8.375e-30 Identity = 121/471 (25.69%), Postives = 220/471 (46.71%), Query Frame = 2
Query: 665 FLSVKKSFDFENPSEKQFNLSLNAIDNGGKSATLQLIVNVIDINDNPPIFQKKIV------NVTIQENTTFPDAILKLNATDLDSGNNAQISYKFSSINRPIIRETFQLQSETGKIYLLKT---LDYELYSEQNFDINVLAIDHGSPQLSDSCIIKVNVTDINDNSPVIEIVHSQPIPENEQITDPALKLYVSDYDSIDNDVKCQAE---KIGRRLKLEQVEKSSYFIYATEIYDYEKEKNLSLSILCQDSGKEPRYTKQLLTIFIKDVNDNRPKFLRSFYRKSINEDQEKLKPFTKVQALDKDSDDFGKVKYSIGLKDRKYFSIDEISGEVRLANEIDRETKDFYNVSVIATDGGG--LKDYSYIEISILDVNDN-----YPKLKSGSSMRVNENLPVGSVVGYISVIDLDLGDNSKVEWTYDFLGNSSSMLQIENCTVYTSTVLDRESIEH---LH-ILITMVDMGYPR 2008
++V++ D E + + LS+ A D SA + +NV D+NDN P + + V + E I + +D D+ N ++ F + P F L++ YLL+T LDYE E F I +A D G P L+ + +++V + D NDN P+ +QP+ E + LY++ + D D AE ++G +++ + + A+ ++D E ++ ++ +D+G ++ + + I D NDN PKF + ++ ++E+ K + D D+ + V SI L D + F +D +G ++ DRE + Y V A D G + + I+++DVNDN YP + + +P GSVV + +D D G N+++++T GN+ + +I+ T + L+ + E LH +++ + D+GYP+
Sbjct: 310 LITVQRPLDREETANHK--LSVLASDGSSSSARATVTINVTDVNDNAPNIDLRYIISPTNGTVLLSEKDPVNTKIALITVSDKDTDVNGKV-ICFIEKDVP-----FHLKAVYDNQYLLETSALLDYEGTKEYIFKI--VASDSGKPSLNQTALVRVRLEDENDNPPIF----TQPVIELTVSENNKRDLYLTTITATDEDSGRNAEIVYQLGPNASFFDLDRKTGVLTASRVFDREDQERFLFTVTARDNGTRALQSQAAVIVTILDQNDNSPKFTHNHFQFFVSENLPKYSTVGVITVTDADAGENAVVSLSI-LNDNENFILDPYTGVIKSNVSFDREQQSSYTFDVRAVDSGHPPCSSAAKVTINVIDVNDNPPIVIYPPSNTSFKLVPLSAIP-GSVVAEVFAVDGDTGMNAELKYTI-VNGNNKGLFRIDPVT--GNITLEEKPTEADSGLHRLVVNISDLGYPK 761
BLAST of Protocadherin alpha-2 vs. Ensembl Sea Lamprey
Match: si:ch211-199f5.1 (protocadherin 8 [Source:HGNC Symbol;Acc:HGNC:8660]) HSP 1 Score: 201.83 bits (512), Expect = 1.167e-53 Identity = 193/652 (29.60%), Postives = 299/652 (45.86%), Query Frame = 2
Query: 203 ISKLPSRFPRGSYQIITRRSSFTKFNQYFRISDSGEIRITKVFDRDDVNNVCGPLGCCDKPSCEIVLDIIVTVIPKNERIPVKVVIVIEDENDNAPDXXXXXXXXXXXXNDATQLDHNLPKALDKDCPIYGIKNYSLSGNKVEYFSLKIRQFQ-----PFLSVKKSFDFENPSEKQFNLSLNAIDNGG--KSATLQLIVNVIDINDNPPIFQKKIVNVTIQENTTFPDAILKLNATDLDSGNNAQISYKFSSINRPIIRETFQLQSETGKIYLLKTLDYELYSEQNFDINVLAIDHGSPQLSDSCIIKVNVTDINDNSPVIE---IVHSQP----IPENEQITDPALKLYVSDYDSIDNDVKCQAEKIGRRLKLEQVEKSSYFIYATEIYDYEKEKNLSLSILCQDSGKEPRYTKQLLTIFIKDVNDNRPKFLRSFYRKSINEDQEKLKPFTKVQALDKDSDDFGKVKYSI------GLKDRKYFSIDEISGEVRLANEIDRETKDFYNVSVIATDGG--GLKDYSYIEISILDVNDN-----YPKLKSGSS-MRVNENLPVGSVVGYISVIDLDLGDNSKVEWTYDFLGNSSSMLQIE--NCTVYT--STVLDRESIEHLHILITMV-DMGYPRLTSSATITVSVIDENDN 2059
+++ PSR R + RR F+ + +D G + +V DR+ C PSC I D++ T +P+ V + + D ND+APDF+ S + I E+ A L A D D ++ Y L N E F L +R L VK D E E ++ L L A D G +S T + + V+D NDN P+F + NVT++E+ T +L LNATD+D G N ++ Y FSS +R FQL +TGK+ L LD+EL SE ++I++ A D G + C + V+V DINDN+P I+ I+ S+ + E + VSD DS +N + + KL + Y + D E+ + L + D G PR + T+ + D NDN P+F RS Y S+ E+ T V A D D++ G + Y++ G Y SI+ SG + +D E V A D G L + + + I+D NDN +P L++G+ +R+ + +G +V + D D N ++ + GN ++ +I V+T ++V D + H L+ MV D G P L+++A I + V D
Sbjct: 56 VAEHPSRHFR-----LMRRDDFSLV--HVEEAD-GTVSAREVIDREQQ--------CGQAPSCVIRFDVLCT-LPRGLFQLVHAEVELLDINDHAPDFARSEMHVEISESVALGTRVPLEGARDLDVGGNALRAYHLDEN--ERFGLALRARTDGAKYAELVVKSRLDREQ--EGEYTLQLTAWDGGDPPRSGTTLVRITVLDSNDNSPVFAQTSCNVTVREDATPGTVLLTLNATDVDEGPNGEVVYSFSSPVDAEVRRLFQLDPKTGKLSLKGQLDHELNSE--YEISIQARDMGPSSIPAHCKVLVHVEDINDNAPEIKLDFIMQSRGDTVFVSEGAAYESFVGLVTVSDIDSAENGLVACHLRGHPHFKLLPY-RDDYVVVTNSSLDREQMADYFLVLEASDGGTPPRVAARQFTVRLLDENDNEPRFHRSTYEASLLENNSPGAYVTTVTAWDADAEHNGMIAYNVVESEVAGASVSTYVSINPSSGAIYALRPLDYEAMTSLTFQVQARDDGVPPLVTNATVSVRIVDENDNAPVVTHPPLRNGTGVVRLPRDAGLGYLVTVVRARDSDSEANGELSYRI-VQGNERNLFRINRLGGEVFTNAASVTDAAASATRHSLVVMVRDRGSPALSATAAIEIRVGAHGDG 682 HSP 2 Score: 111.309 bits (277), Expect = 4.339e-25 Identity = 135/537 (25.14%), Postives = 225/537 (41.90%), Query Frame = 2
Query: 776 VNVIDINDNPPIFQKKIVNVTIQENTTFPDAILKLNATDLDSGNNAQISYKFSSINRPIIRETFQLQSET-GKIYLLKTLDYELYSEQN--FDINVLAIDHGSPQLSDSCIIKVNVTDINDNSPVIEIVHSQ-PIPENEQITDPALKLYVSDYDS-------------IDNDVKCQAEKIGRRLKLEQVEKSSYFIYATEIYDYEKEKNLSLSILCQDSGKE--PRYTKQLLTIFIKDVNDNRPKFLRSFYRKS------INEDQEKLKPFTKVQALDKDSDDFGKVKYSIGLKDRKYFSIDEISGE--VRLANEIDRETKDFYNVSVIATDGGGLKDYSYIE--ISILDVNDNYPKL-KSGSSMRVNENLPVGSVVGYISVIDLDLGDNSKVEWTY---DFLGNSSSM---LQIENCTVYTSTVLDRESIEHLHILITMVDMGYPRLTSSATITVSVIDENDNIPKVIYP--KTGSLVEEREMDHIAVNSPKYTT----VLSIKSFDPDLGINGDVLYHILPSNGSQYFIINQTSG 2260
V ++DIND+ P F + ++V I E+ + A DLD G NA +Y R L++ T G Y + L EQ + + + A D G P S + ++++ V D NDNSPV + E+ L L +D D +D +V+ +L Q++ + + D+E +SI +D G P + K L + ++D+NDN P+ F +S ++E V D DS + G V + L+ +F + + V + +DRE Y + + A+DGG + + + +LD NDN P+ +S + EN G+ V ++ D D N + + + G S S + + +Y LD E++ L + D G P L ++AT++V ++DENDN P V +P + G+ V V P+ V +++ D D NG++ Y I+ N F IN+ G
Sbjct: 124 VELLDINDHAPDFARSEMHVEISESVALGTRVPLEGARDLDVGGNALRAYHLDENER----FGLALRARTDGAKYAELVVKSRLDREQEGEYTLQLTAWDGGDPPRSGTTLVRITVLDSNDNSPVFAQTSCNVTVREDATPGTVLLTLNATDVDEGPNGEVVYSFSSPVDAEVR----------RLFQLDPKTGKLSLKGQLDHELNSEYEISIQARDMGPSSIPAHCKVL--VHVEDINDNAPEIKLDFIMQSRGDTVFVSEGAAYESFVGLVTVSDIDSAENGLV--ACHLRGHPHFKLLPYRDDYVVVTNSSLDREQMADYFLVLEASDGGTPPRVAARQFTVRLLDENDNEPRFHRSTYEASLLENNSPGAYVTTVTAWDADAEHNGMIAYNVVESEVAGASVSTYVSINPSSGAIYALRPLDYEAMTSLTFQVQARDDGVPPLVTNATVSVRIVDENDNAPVVTHPPLRNGTGV---------VRLPRDAGLGYLVTVVRARDSDSEANGELSYRIVQGNERNLFRINRLGG 633
BLAST of Protocadherin alpha-2 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000010725.1 (pep scaffold:Pmarinus_7.0:GL479425:26296:30457:-1 gene:ENSPMAG00000009713.1 transcript:ENSPMAT00000010725.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 200.29 bits (508), Expect = 5.313e-53 Identity = 201/732 (27.46%), Postives = 324/732 (44.26%), Query Frame = 2
Query: 302 SGEIRITKVFDRDDVNNVCGPLGCCDKP----SCEIVLDIIVTVIPK-----NERIPVKVVIVIEDENDNAPDXXXXXXXXXXXXNDATQLDHNLPKALDKDCPIYGIKNYSLS-----GNKVEYFSL-----------------KIRQFQPFLSVKKSFDFENPSEKQFNLSLNAIDNGGK--SATLQLIVNVIDINDNPPIFQKKIVN-VTIQENTTFPDAILKLNATDLDSGNNAQISYKF-SSINRPIIRETFQLQSETGKIYLLKTLDYELYSEQNFDINVLAIDHGSPQLSDSCIIKVNVTDINDNSPVIEIVHSQ---------PIPENEQITDPALKLYVSDYD---SIDNDVKCQAEKIGRRLKLEQVEKSSYFIYATEIYDYEKEKNLSLSILCQDSGKEPRYTKQL-LTIFIKDVNDNRPKFLR--------SFYRKSINEDQEKLKPFTKVQALDKDSDDFGKVKYSI-----GLKDRKYFSIDEISGEVRLANEIDRETKDFYNVSVIATDGGG--LKDYSYIEISILDVNDNYPKLKSGSSMR-------VNENLPVGSVVGYISVIDLDLGDNSKV------EWTYDFLGNSSSMLQIENCTVYTSTVLDRESIEHLHILITMVDMGYPRLTSSATITVSVIDENDNIPKVIYPKTGSLVEEREMDHIAVNSPKYTTV-LSIKSFDPDLGINGDVLYHILPSNGSQYFIINQTSGVL 2266
SGE+ + DR+ + C ++P S + + V + K N R+ + V +++ D ND+AP F +SI E++A LP+A+D D I++Y +S G ++ FSL + L +++ D E + + L L D G S ++ L + V+D NDN P+F V I E++ ++++L A D D+G N I+Y F + + + + TG + + + + + V+A D G S S + V + D NDN+PV E++ Q I EN P + + VSD D S DV+ + +L K + + T + DYE+ + ++S+L D G P+ +K L L I + D+NDN P F+ + Y S+ E+ + A D DS G + +++ G + FS++ +G++ LA +DRE + Y +SV A DGG K + + +++LD NDN P S+ V E VG+ VG +S DLD GDN++V E D++G + V T VLDRE + + VD G P L++S ++++V D NDN P + P T H+ SP V +S+ + D D G NG LY I+ N F++N SG L
Sbjct: 80 SGELSVALRLDREAL--------CMEEPDACRSTGFMHTVQVAAMAKGQGSSNLRL-LDVQLLVRDINDHAPAFRAPHLNVSISESEAVGRRVPLPRAIDPDAGTNSIQHYRISAASGDGLQLGPFSLVESDDDDDGGGVGVDGDGGMGHRALLELREQLDRE--AVPSYELLLWGEDGGNPKLSGSVLLTIVVVDANDNAPVFVDPPTRPVRITEHSKVGTSVVQLRAADPDAGPNGAIAYSFHTKLTSLATQAALHVDGTTGLVTVRNAEKLDRETMPVHRLVVVARDGGQLSRSASVTVTVELNDDNDNAPVFEVIALQGEYLPDGGVKIVENLPSGTPVVLISVSDPDLGSSGTVDVRLEFPT---GAELASPNKVQFLLKTTRLLDYEEAQQYNVSVLAADRGT-PKLSKLLNLIISVVDINDNTPVFMNPASIEGDVAVYEVSLRENGPAGTVVLNLLATDADSGPNGAITFTLSELAGGESVAELFSLNMRTGQLTLATPLDREKRMRYELSVEACDGGSPQRKARAIVRVTVLDENDNAPTFVGVSNSTNCMYQFFVEEETSVGTYVGTVSTSDLDEGDNARVALNLVREAGPDWIGGAG---DTPGGVVRTLVVLDREDRVQYELSVRAVDSGRPALSASCRVSITVSDTNDNAPVITSPNTND-----TWKHVRTFSPAGMLVGVSVTANDIDAGDNGRPLYEIIGGNPKGIFLLNADSGAL 788 HSP 2 Score: 75.0998 bits (183), Expect = 7.308e-14 Identity = 81/333 (24.32%), Postives = 135/333 (40.54%), Query Frame = 2
Query: 1418 IFIKDVNDNRPKFLRSFYRKSINEDQEKLKPFTKVQALDKDSDDFGKVKYSIGLKDRKYFSIDEIS------------------------GEVRLANEIDRETKDFYNVSVIATDGGG--LKDYSYIEISILDVNDNYPKLKSGSS--MRVNENLPVGSVVGYISVIDLDLGDNSKVEWTYDFLGNS---SSMLQIEN----CTVYTSTVLDRESIEHLHILITMVDMGYPRLTSSATITVSVIDENDNIP--KVI------YPKTGSLVEEREMDHIAVNSPKYTTVLSIKSFDPDLGINGDVLYHILPSNGSQYFIINQTSGVLKTTWIYD 2287
+ ++D+ND+ P F SI+E + + +A+D D+ Y I + S + L ++DRE Y + + DGG L + I ++D NDN P + +R+ E+ VG+ V + D D G N + +++ S + L ++ TV + LDRE++ +++ D G ++S T+TV + D+NDN P +VI P G + E N P T V+ I DPDLG +G V + G++ N+ +LKTT + D
Sbjct: 132 LLVRDINDHAPAFRAPHLNVSISESEAVGRRVPLPRAIDPDAGTNSIQHYRISAASGDGLQLGPFSLVESDDDDDGGGVGVDGDGGMGHRALLELREQLDREAVPSYELLLWGEDGGNPKLSGSVLLTIVVVDANDNAPVFVDPPTRPVRITEHSKVGTSVVQLRAADPDAGPNGAIAYSFHTKLTSLATQAALHVDGTTGLVTVRNAEKLDRETMPVHRLVVVARDGGQLSRSASVTVTVELNDDNDNAPVFEVIALQGEYLPDGGVKIVE--------NLPSGTPVVLISVSDPDLGSSGTVDVRLEFPTGAELASPNKVQFLLKTTRLLD 456
BLAST of Protocadherin alpha-2 vs. Ensembl Sea Lamprey
Match: pcdh11 (protocadherin 11 [Source:ZFIN;Acc:ZDB-GENE-140106-21]) HSP 1 Score: 198.364 bits (503), Expect = 2.903e-52 Identity = 195/674 (28.93%), Postives = 313/674 (46.44%), Query Frame = 2
Query: 341 DVNNVCGPLGCCDKPSCEIVLDIIVTVIPKNERIPVKVVIV---IEDENDNAPDXXXXXXXXXXXXNDATQLDHNLPKALDKDCPIYGIKNYSL---SGNKVEYFSLKIRQFQ-----PFLSVKKSFDFENPSEKQ-FNLSLNAIDNGG--KSATLQLIVNVIDINDNPPIFQKKIVNVTIQENTTFPDAILKLNATDLDSGNNAQISYKFSSINRPII-----RETFQLQSETGKIYLLKTLDYELYSEQNFDINVLAIDHGSPQLSDSCIIKVNVTDINDNSPVIEIVH-SQP------IPENEQITDPALKLYVSDYD-SIDNDVKCQAEKIGRRLKLEQVE-KSSYFIYATEIYDYEKEKNLSLSILCQDSGKEPRYTKQLLTIFIKDVNDNRPKFLRSFYRKSINEDQEKLKPFTKVQALDKDSDDFGKVKYSIGLKDRKYFSIDEISGEVRLANEIDRETKDFYNVSVIATDGG--GLKDYSYIEISILDVNDNYPKLKSGS-SMRVNENLPVGSVVGYISVIDLDLGDNSKVEWTYDFLGNSSSML---QIENCTVYTSTVLDRESIEHLHILITMVDMGYPRLTSSATITVSVIDENDNIPKVIYPKTGSLVEEREMDHIAVNSPKYTTVLSIKSFDPDLGINGDVLYHILPSNGSQYFIINQTSG 2260
D +CG P E +D+ V V+P K++ V +ED NDNAP F+ T+S+ EN + A D D G++ Y L V F L + + P+L V+KS D E E+Q + ++L A+D G S + L +NV D NDN P+F + VNV I EN+ +++L+A+D D+G+NA++ Y+ + + F+L +G + + L+ E + I +LA D G + + + V VTD+NDNSP IEI P I E + P + VSD D + V C +L+++ + Y + E DYE + + I D+G +TI + D NDN P F Y+ S+ E+ K V A D+D D ++ Y +G F +D +G + L ++DRE K Y+ +++A D G L+ + + +++LDVNDN P+ VNEN+P S VG ++V D D G+N +V + LG + L E+ + ++ DRE + + + D G P +S+ + + V+D NDN P V+ P + + + + + T V + + D D IN ++ YHI+ N F I+ G
Sbjct: 103 DREALCG----GQDPGDECHVDVQVGVLPVQPGPFFKLIEVRINVEDINDNAPAFAAPVLTVSVPENAPAGKRFPIQPANDPDSEANGVRRYELLPSDPATVSAFELSVTETANGEKVPYLVVRKSLDRE---ERQLYEMNLRAVDGGSPPHSGSAVLRINVTDTNDNSPVFDQAEVNVEIPENSPVGTHVVQLHASDRDAGSNAEVVYRLGTSTGGAGSGQGGKRLFRLDQNSGLVTVNGLLNRE--ESPVYRIIILATDKGPEPVPATATVTVTVTDVNDNSPTIEIRDIVAPVNGVIYISEASHVNLPVALITVSDPDIGANGAVTCYIYNPEVPFQLKKLTYPNQYLLETRETLDYETKNEYVVQIKAADAGATSLSRTMSVTIKLLDSNDNAPVFTEPTYKVSVPENNVIGKHLITVSATDRDMDKNAEMVYFLGPDAPTMFHMDPETGIISLTEQLDREKKANYSFTILAKDQGIPVLEGNATVIVNVLDVNDNRPRFSLAEFDFYVNENVPKHSTVGMVTVADSDEGENGRVRLS--ILGTDNRQLFSIDPESGMIRSNVGFDREQRHYYVLEVQATDGGEPVRSSTVKVVIHVMDINDNSPIVLMPPSNTTYK-----FVVPRTLPGTIVTEVSAVDNDAEINAELRYHIVGGNPHNLFHIDPVIG 760
BLAST of Protocadherin alpha-2 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000008517.1 (pep scaffold:Pmarinus_7.0:GL476786:43429:129410:1 gene:ENSPMAG00000007697.1 transcript:ENSPMAT00000008517.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 181.8 bits (460), Expect = 1.525e-46 Identity = 178/647 (27.51%), Postives = 295/647 (45.60%), Query Frame = 2
Query: 443 PVKVVIVIEDENDNAPDXXXXXXXXXXXXNDATQLDHNL-PKALDKDCPIYGIKNYS---LSGNKVEYFSLKIRQF--QPFLSVKKSFDFENPSEKQFNLSLNAIDNGG--KSATLQLIVNVIDINDNPPIFQKKIVNVTIQENTTFPDAILKLNATDLDSGNNAQISYKFSSINRPIIRETFQLQSETGKIYLLKTLDYELYSEQNFDINVLAIDHGSPQLSDSCIIKVNVTDINDNSPVIEIVHSQPIPENEQITDPALK------LYVSDYDSIDNDVKCQAEKIGRRLKLEQVEKSSYFIYATEI-----------YDYEKEKNLSLSILCQDSGKE-PRYTKQLLTIFIKDVNDNRPKFLRSFYRKSINEDQEKLKPFTKVQALDKDSDDFGKVKYSI-GLKDRKYFSIDEISGEVRLANEIDRETKDFYNVSVIATDGGGLKDYSY--IEISILDVNDNYPKLKSGS--SMRVNENLPVGSVVGYISVIDLDLGDNSKVEWTY--DFLGNSSSMLQIENCTVYTSTV--LDRESIEHLHILITMVDMGYPRLTSSATITVSVIDENDNIPKVIYPKT--GSLVEEREMDHIAVNSPKYTTVLSIKSFDPDLGINGDVLYHILPSNGSQYFIINQTSGVLKT 2272
P +V +V+ D NDNAP F E F+ DA L A+D+D G+ +++ +SGN+ E + R + FL + + + + + L++ A D G + LQ+ V V D NDNPP F+K ++ E++ A+ DL ++ F +TG + + LD+E + + + +++ A D G+P LS + + D+NDN P I V+ P + + + A + V+D DS + + +G E+ + ++A + D E+ +L+IL D+GK R L +++ DVND+ P+F S Y +++E V A+D DS K++YSI D +FS+DE +G V ++DRE +++ A D G +Y + +++LDVND P + V +LP G V +S D DLG+N V + + D M ++++ T +T+ LDRE +E +++ D G P L S+A +TV V D NDN P V YP S++E N P T V ++ + DPD G NG V Y + + ++ F +N +G + T
Sbjct: 6 PTEVRVVVGDVNDNAPSFPEPGVMEVAFKEDAAVGRQVLLDTAVDRDVGPNGVNHHAYKIVSGNE-EGRLVPPRPVTKRAFLHLATTGPLDREANPSYALAVQAEDGGSPRRYGRLQVNVTVQDANDNPPAFEKPAYRASVAEDSPVGAAL-----RDLLHRGRGPLAVPF--------------DPKTGMVSTRQPLDFE--ARRQYTLSLRAADGGNPPLSGRATAVIQLLDVNDNDPAIRFVYLPPAARSASVDESAAPGTVAALVTVTDADSPTANGELSVSIVGGN------ERGHFVLHAPGVPGLRVLKVASQLDRERIPMYNLTILASDNGKPVARSATASLVVYVNDVNDHAPRFALSAYAAALSEGAPAGSYVKDVTAMDADSGLNAKLRYSIVSGNDLGWFSVDESTGLVTTDGKVDREVASSVVLNISAQDQGAQPKTAYTSLTVTLLDVNDEPPLFTQTKYVATAVENSLP-GLFVVSVSAADSDLGENGTVRYNFDPDMPAQYREMFRLDSLTGKVTTLKSLDREELEEYPLVVQAQDRGSPPLGSTAKVTVVVGDLNDNHP-VFYPVQYFASILE---------NEPGGTAVTTVTATDPDRGANGTVRYQLTAGDAAR-FQVNAVTGAVST 612 HSP 2 Score: 181.8 bits (460), Expect = 1.705e-46 Identity = 158/594 (26.60%), Postives = 274/594 (46.13%), Query Frame = 2
Query: 563 KALDKDCPIYGIKNYSLS-GNKVEYFSLKIRQFQPFLSVKKSFDFENPSEKQFNLSLNAIDNGGK--SATLQLIVNVIDINDNPPIFQKKIVNVTIQENTTFPDAILKLNATDLDSGNNAQISYKFSSINRPIIRETFQLQSETGKIYLLKTLDYELYSEQ----NFDINVLAIDHGSPQ-LSDSCIIKVNVTDINDNSP-VIEIVHSQPIPENEQITDPALKLYVSDYDSIDNDVKCQAEKIGRRLKLEQVEKSSYFIYATEIYDYEKEKNLSLSILCQDSGKEPRYTKQLLTIFIKDVNDNRPKFLRSFYRKSINEDQEKLKPFTKVQALDKDSDDFGKVKYSI-GLKDRKYFSIDEISGEVRLANEIDRETKDFYNVSVIATDGG--GLKDYSYIEISILDVNDNYPKLKSGSSM-RVNENLPVGSVVGYISVIDLDLGDNSKVEWT--YDFLGNSSSMLQIENCTVYTSTVLDRESIEHL-HILITMVDMGYP---RLTSSATITVSVIDENDNIPKVIYPKTGSLVEEREMDHIAVNSPKYTTVLSIKSFDPDLGINGDVLYHILPSNGSQYFIINQTSGVLKTTWIYD 2287
+A DKD G Y + GN E F + P + ++ + + ++++L+++A+D G + S+++ + V V+D+NDN P+F E + + ATD D+G+N ++Y F +P + F+L SETG+I L+ D E Q +F +V+A D G P+ L D ++V V D+NDN P + V+ + E+ L++ SD D N A G V+ S+ I D E+ + +L + DSG P + + + D NDN P+F S E + + A D+D+ G V+Y+I F+ID +G V LA +D ET+ Y ++V A DGG + + + + D NDN P G + EN+P+G+ V ++ D D N ++ ++ F + + E+ + T+ +DRE L + + D P R ++ +TV V DENDN P+ + P T LV+ + + + V ++++ DPD N V Y + + + F +++ +G+++T+ D
Sbjct: 781 RATDKDSGKNGEVKYEIGEGNGGEKFGIF-----PDGQLYVRYELDRETREEYSLTVSAMDTGVEPLSSSVTVNVTVLDVNDNKPLFNSSSYVFHFCEEQEVGSLVGAVQATDADAGSNGGVTYSF---EKPQV--NFELDSETGRIASLRVFDREALIRQGGAASFSFSVVATDGGRPKPLQDRATVQVFVQDVNDNPPQFAKSVYQASVSESASNLTQLLRVTASDVDEGVNGALRYAINEGNEGGKFTVDASTGQITLLGSLDREETASYTLVVSATDSGTSPLAASCTVAVQVLDENDNPPRFTESLLSVDALESTRVGELLITLTASDEDTGPSGDVRYAIVAGNTHATFAIDRSTGSVFLARRLDFETQRLYRLNVSAEDGGRPPRSSATILVVHVRDFNDNPPAFLPGDVFASIMENIPIGTRVITVTARDPDADVNGELHYSIARQFPPGAHFTIDPESGEICTAAEIDREVTGGLFEVTVRATDKAIPVHTRRSALKNVTVLVTDENDNAPRFVTP-TAILVD-------GLRAAAGSVVGTLQASDPDEAENAAVRYAVTGGDAAILFRLDRRTGIIETSTELD 1356 HSP 3 Score: 166.392 bits (420), Expect = 1.019e-41 Identity = 133/433 (30.72%), Postives = 217/433 (50.12%), Query Frame = 2
Query: 716 FNLSLNAIDNGGKSATLQ----LIVNVIDINDNPPIFQKKIVNVTIQENTTFPDAILKLNATDLDSGNNAQISYKFSSINRPIIRETFQLQSETGKIYLLKTLDYELYSEQNFDINVLAIDHGSPQLSDSCIIKVNVTDINDNSP-VIEIVHSQPIPENEQITDPALKLYVSDYDSIDNDVKCQAEKIGRRLKLEQVEKSSYFIYATEIYDYEKEKNLSLSILCQDSGKEPRYTKQLLTIFIKDVNDNRPKFLRSFYRKSINEDQEKLKPFTKVQALDKDSDDFGKVKYSIG--LKDRKYFSIDEISGEVRLANEIDRE-TKDFYNVSVIATDGG--------GLKDYSYIEISILDVNDNYPKLKSGSSMRVNE-NLPVGSVVGYISVIDLDLGDNSKVEWTYDFLGNSSSMLQIENCT--VYTSTVLDRES 1957
F+ S+ A D GG+ LQ + V V D+NDNPP F K + ++ E+ + +L++ A+D+D G N + Y +IN F + + TG+I LL +LD E ++ + V A D G+ L+ SC + V V D NDN P E + S E+ ++ + + L SD D+ + A G +++S+ ++ D+E ++ L++ +D G+ PR + +L + ++D NDN P FL SI E+ V A D D+D G++ YSI +F+ID SGE+ A EIDRE T + V+V ATD LK+ + + + D NDN P+ + +++ V+ GSVVG + D D +N+ V + G+++ + +++ T + TST LDRES
Sbjct: 937 FSFSVVATD-GGRPKPLQDRATVQVFVQDVNDNPPQFAKSVYQASVSESASNLTQLLRVTASDVDEGVNGALRY---AINEGNEGGKFTVDASTGQITLLGSLDRE--ETASYTLVVSATDSGTSPLAASCTVAVQVLDENDNPPRFTESLLSVDALESTRVGELLITLTASDEDTGPSGDVRYAIVAGNTHATFAIDRSTGSVFLARRLDFETQRLYRLNVSAEDGGRPPRSSATILVVHVRDFNDNPPAFLPGDVFASIMENIPIGTRVITVTARDPDADVNGELHYSIARQFPPGAHFTIDPESGEICTAAEIDREVTGGLFEVTVRATDKAIPVHTRRSALKN---VTVLVTDENDNAPRFVTPTAILVDGLRAAAGSVVGTLQASDPDEAENAAVRYAVTG-GDAAILFRLDRRTGIIETSTELDRES 1359 HSP 4 Score: 163.31 bits (412), Expect = 8.850e-41 Identity = 174/626 (27.80%), Postives = 283/626 (45.21%), Query Frame = 2
Query: 446 VKVVIVIEDENDNAPDXXXXXXXXXXXXNDATQLDHNLPKALDKDCPIYGIKNYSLSGNKVEYFSLKIRQFQPFLSVKKSFDFENPSEKQFNLSLNAIDNGGKSATLQLIVN--VIDINDNPPIFQKKIVNVTIQENTTFPDAILKLNATDLDSGNNAQISYKFSSINRPIIRETFQLQSETGKIYLLKTLDYELYSEQNF-DINVLAIDHGSPQLSDSCIIKVNVTDINDNSPVIEIV-HSQPIPENEQITDPALKLYVSDYDSIDN-DVKCQAEKIGRRLKLEQVEKSSYF----IYATEIYDYEKEKNLSLSILCQDSGKEPRYTKQLLTIFIKDVNDNRPKFLRSFYRKSINEDQEKLKPFTKVQALDKDSDDFGKVKYSIGLKDRKYFSIDEISGEVRLANEIDRET------KDFYNVSVIATDGG---GLKDYSYIEISILDVNDNYPKL-KSGSSMRVNENLPVGSVVGYISVIDLDLGDNSKVEWTYDFLGNSSSMLQIENCTVYTSTV--LDRESIEHLHILITMVDMGYPRLTSSATITVSVIDENDNIPKVIYPKTGSLVEEREMDHIAVNSPKYTTVLSIKSFDPDLGINGDVLYHILPSNGSQYFIINQTSG 2260
KV +V+ D NDN P F + SI EN+ A D D G Y L+ F ++ +S + S D E + L + A+D G A IV V D D PP F + + + EN + ++A+ LD NA ++Y S ++ R +F ++ G+I+ +D E EQ F + V+A G ++ + V V D+N+++PV + + I E+E + + +D DS N +VK + IG + EK F +Y D E + SL++ D+G EP + + + + DVNDN+P F S Y E+QE VQA D D+ G V YS K + F +D +G + DRE ++ SV+ATDGG L+D + +++ + DVNDN P+ KS V+E+ + + ++ D+D G N + + + GN ++ T + + LDRE ++++ D G L +S T+ V V+DENDN P+ T SL+ ++ V ++++ + D D G +GDV Y I+ N F I++++G
Sbjct: 538 AKVTVVVGDLNDNHPVFYPVQYFASILENEPGGTAVTTVTATDPDRGANGTVRYQLTAGDAARF--QVNAVTGAVSTRVSLDREE--RAVYQLQVTALDGGHLRARSPAIVTITVADAQDTPPTFARDDYSFVVFENVAPGTLVGSVSASTLDL--NANVTYLIVSGDQ---RGSFSIEWSGGRIFTANAIDRE---EQAFYQLRVVANSGG---VAGEASVSVLVHDVNNHAPVFDRASYEVSIAEDEPVNSRFFSVRATDKDSGKNGEVKYE---IG---EGNGGEKFGIFPDGQLYVRYELDRETREEYSLTVSAMDTGVEPLSSSVTVNVTVLDVNDNKPLFNSSSYVFHFCEEQEVGSLVGAVQATDADAGSNGGVTYSF-EKPQVNFELDSETGRIASLRVFDREALIRQGGAASFSFSVVATDGGRPKPLQDRATVQVFVQDVNDNPPQFAKSVYQASVSESASNLTQLLRVTASDVDEGVNGALRYAIN-EGNEGGKFTVDASTGQITLLGSLDREETASYTLVVSATDSGTSPLAASCTVAVQVLDENDNPPRF----TESLLSVDALESTRVGE----LLITLTASDEDTGPSGDVRYAIVAGNTHATFAIDRSTG 1132 HSP 5 Score: 149.828 bits (377), Expect = 1.059e-36 Identity = 146/537 (27.19%), Postives = 228/537 (42.46%), Query Frame = 2
Query: 767 QLIVNVIDINDNPPIFQKKIVNVTIQENTTFPDAILKLNATDLDSGNNAQISYKFSSINRPIIRETFQLQSETGKIYLLKTLDYELYSEQNFDINVLAIDHGSPQLSDSCIIKVNVTDINDNSPVIEI-VHSQPIPENEQITDPALKLYVSDYDSIDNDVKCQAEKIGRRLKLEQVEKSSYFIYA------------TEIYDYEKEKNLSLSILCQDSGKEPRYTKQLLTIFIKDVNDNRPKFLRSFYRKSINEDQEKLKPFTKVQALDKDSDDFGKVKYSIGLKD-RKYFSIDEISGEVRLANEIDRETKDFYNVSVIATDGG---GLKDYSYIEISIL--DVNDNYPKLKSGSSMRVNENLPVGSVVGYISVIDLDLGDNSKVEWTY--------DFLGNSSSMLQIENCTVYTSTV--LDRESIEHLHILITMVDMGYPRLTSSATITVSVIDENDNIPKVIYPKTGSLVEEREMD-HIAVNSPKYTTVLSIKSFDPDLGINGDVLYHILPSNGSQYFIINQTSGVLKTTWIYD 2287
Q+ ++V D+NDNPP+F + + ++ENT + I L+ATD D G NA ++Y S + F + + +G + + LD E ++ + V A D + + V V D NDNSP +S + E+ + + + D D E L E S + A T D E L D G + L + + D NDN P + ED ++ A D D ++++SI D F++ G++ +A +DRE + FYN+ V +D + S + +S++ DVNDN P S S E+ PVG+VV + +D D G NS VE+ G + T V LDRE+ + + + VD G P LTS+AT+ V+V D NDN P+ +P+ RE + IA + P T VL + ++DPD G NG++ Y I + + F ++ G L D
Sbjct: 1501 QVEISVEDVNDNPPVFAVPEMELEVEENTGEGEVIFTLSATDADQGQNALVTYSVLSGSE----GAFVVDAASGVLRASRRLDRE--ERASYLLTVRASDG---THATDARLSVAVRDANDNSPRFSRHAYSFDVAEDAAPDGKTTRAVIGTVLAGDADSGPFGEVT---YALAPSEDSDWADGAFGLHPVTGALNVTRPLDRESRACYVLRARATDGGGLAATAR--LYVNVLDANDNAPSVQNDSLAAEVPEDAPPGTSLLRISATDDDEGVNAELEFSISSGDPEGRFAVGN-DGQLSVARALDRERQSFYNLVVRVSDRARHPPARLSSAVRVSLILTDVNDNAPAFTSPRSALAPEDSPVGAVVATVQAVDPDSGRNSYVEYALATDGEEGGGGAGAGPGPFALNTVTGEVRLVRELDREARQSYALTVLAVDKGRPPLTSTATLAVTVGDANDNAPR--FPR-------REYEAAIAEDEPPGTEVLRLSAWDPDEGANGELRYDIASGDPTGDFRLDPVLGTLAVARPLD 2013 HSP 6 Score: 149.828 bits (377), Expect = 1.133e-36 Identity = 143/542 (26.38%), Postives = 246/542 (45.39%), Query Frame = 2
Query: 446 VKVVIVIEDENDNAPDXXXXXXXXXXXXNDATQLDHNLPKAL-------DKDCPIYGIKNYSLSGNKVEYFSLKIRQFQPF---LSVKKSFDFENPSEKQFNLSLNAIDNGGKSATLQLIVNVIDINDNPPIFQKKIVNVTIQENTTFPDAILKLNATDLDSGNNAQISYKFSSINRPIIRETFQLQSETGKIYLLKTLDYELYSEQNFDINVL-AIDHGSPQLSDSCIIKVNVTDINDNSPVIEIVHSQPIPENEQITDPALKLYVSDYDSIDN---------DVKCQAEKIGRRLKLEQVEKSSYFIYATEIYDYEKEKNLSLSILCQDSGKEPRYTKQLLTIFIKDVNDNRPKFLRSFYRKSINEDQEKLKPFTKVQALDKDSDDFGKVKYSIGLKDRKY-FSIDEISGEVRLANEIDRETKDFYNVSVIATDGGG--LKDYSYIEISILDVNDNYPKLK-SGSSMRVNENLPVGSVVGYISVI--DLDLGDNSKVEWTYDFLGNSSSMLQIENCTVYTSTVLDRESIEHLHILITMVD 1993
++ + + D NDN+P FS +++ + E+ A D +A+ D D +G Y+L+ ++ ++ P L+V + D E S + L A D GG +AT +L VNV+D NDN P Q + + E+ ++L+++ATD D G NA++ + SS + P R F + ++ G++ + + LD E S N + V H +LS + + + +TD+NDN+P S PE+ + + D DS N D + G + + + D E ++ +L++L D G+ P + L + + D NDN P+F R Y +I ED+ ++ A D D G+++Y I D F +D + G + +A +DRE Y ++V A DGGG D + + +++ DVND P + S ++ EN G V + V+ D DLG + +V + + + + V+ LDRE+ ++IT D
Sbjct: 1601 ARLSVAVRDANDNSPRFSRHAYSFDVAEDAAP--DGKTTRAVIGTVLAGDADSGPFGEVTYALAPSEDSDWADGAFGLHPVTGALNVTRPLDRE--SRACYVLRARATDGGGLAATARLYVNVLDANDNAPSVQNDSLAAEVPEDAPPGTSLLRISATDDDEGVNAELEFSISSGD-PEGR--FAVGND-GQLSVARALDRERQSFYNLVVRVSDRARHPPARLSSAVRVSLILTDVNDNAPAFTSPRSALAPEDSPVGAVVATVQAVDPDSGRNSYVEYALATDGEEGGGGAGAGPGPFALNTVTGEVRLVRELDREARQSYALTVLAVDKGRPPLTSTATLAVTVGDANDNAPRFPRREYEAAIAEDEPPGTEVLRLSAWDPDEGANGELRYDIASGDPTGDFRLDPVLGTLAVARPLDRERTASYELAVRARDGGGPARSDTASVRVTLSDVNDCSPAFQLSPYTVHARENT-QGPPVLILQVVARDDDLGSSGQVTYAAAGGNDGGAFSVSPDGHVHLLRSLDREAQPQHVLIITATD 2133 HSP 7 Score: 143.28 bits (360), Expect = 1.287e-34 Identity = 148/566 (26.15%), Postives = 245/566 (43.29%), Query Frame = 2
Query: 611 LSGNKVEYFSLKIRQFQPFLSVKKSFDFENPSEKQFNLSLNAIDNG---GKSATLQLIVNVIDINDNPPIFQKKIVNVTIQENTTFPDAILKLNATDLDSGNNAQISYKFSSINRPIIRETFQLQSETGKIYLLKTLDYELYSEQNFDINVLAIDHGSPQLSDSCIIKVNVTDINDNSPVIEIVHSQPIPENEQITDPAL-KLYVSDYDS-----------IDNDVKCQAEKIGRRLKLEQVEKSSYFIYATEIYDYEKEKNLSLSILCQDSGKEPRYTKQLLTIFIKDVNDNRPKFLRSFYRKSINEDQEKLKPFTKVQALDKDSDDFGKVKYSIGLKDRKYFSIDEISGEVRLANEIDRETKDFYNVSVIATDGGGLKDYS--YIEISILDVNDNYPKL-KSGSSMRVNENLPVGSVVGYISVIDLDLGDNSKVEWTYDFL-GNSSSMLQIE--NCTVYTSTVLDRESIEHLHILITMVDMGYPRLTSSATITVSVIDENDNIPKVIYPKTGSLVEEREMDHIAVNSPKYTTVLSIKSFDPDLGINGDVLYHILPSNGSQYFII 2245
+ GN+ +F L +K + + +NL++ A DNG +SAT L+V V D+ND+ P F + E + + A D DSG NA++ Y S N F + TG + +D E+ S + +N+ A D G+ + + V + D+ND P+ ++ + + + P L + VS DS D D+ Q ++ R ++ + + + D E+ + L + QD G P + +T+ + D+NDN P F Y SI E++ T V A D D G V+Y + D F ++ ++G V +DRE + Y + V A DGG L+ S + I++ D D P + S V EN+ G++VG +S LDL N TY + G+ IE ++T+ +DRE + + G + A+++V V D N++ P ++ + V IA + P + S+++ D D G NG+V Y I NG + F I
Sbjct: 271 VGGNERGHFVLHAPGVPGLRVLKVASQLDRERIPMYNLTILASDNGKPVARSATASLVVYVNDVNDHAPRFALSAYAAALSEGAPAGSYVKDVTAMDADSGLNAKLRYSIVSGND---LGWFSVDESTGLVTTDGKVDREVAS--SVVLNISAQDQGAQPKTAYTSLTVTLLDVNDEPPLF--TQTKYVATAVENSLPGLFVVSVSAADSDLGENGTVRYNFDPDMPAQYREMFR------LDSLTGKVTTLKSLDREELEEYPLVVQAQDRGSPPLGSTAKVTVVVGDLNDNHPVFYPVQYFASILENEPGGTAVTTVTATDPDRGANGTVRYQLTAGDAARFQVNAVTGAVSTRVSLDREERAVYQLQVTALDGGHLRARSPAIVTITVADAQDTPPTFARDDYSFVVFENVAPGTLVGSVSASTLDLNAN----VTYLIVSGDQRGSFSIEWSGGRIFTANAIDREEQAFYQLRVVANSGG---VAGEASVSVLVHDVNNHAP--VFDRASYEVS------IAEDEPVNSRFFSVRATDKDSGKNGEVKYEIGEGNGGEKFGI 808 HSP 8 Score: 129.798 bits (325), Expect = 1.722e-30 Identity = 105/395 (26.58%), Postives = 188/395 (47.59%), Query Frame = 2
Query: 1076 PQLSDSCIIKVNVTDINDNSPVIEIVHSQ-PIPENEQITDPALKLYVSDYDSIDNDVKCQAEKIGRRLKLEQVEKSSYFIYATEIYDYEKEKNLSLSILCQDSGKEPRYTKQLLTIFIKDVNDNRPKFLRSFYRKSINEDQEKLKPFTK-----VQALDKDSDDFGKVKYSIGLKDRK-----YFSIDEISGEVRLANEIDRETKDFYNVSVIATDGGGLKDYSYIEISILDVNDNYPKLKSGS-SMRVNENLPVGSVVGYISVIDLDLGDNSKVEWTYDFLGNSSSMLQIEN-CTVYTSTVLDRESIEHLHILITMVDMG-YP--RLTSSATITVSVIDENDNIPKVIYPKTGSLVEEREMDHIAVNSPKYTTVLSIKSFDPDLGINGDVLYHI 2212
P +S ++++V D+NDN PV + + + EN + L +D D N + + G V+ +S + A+ D E+ + L++ D T L++ ++D NDN P+F R Y + ED T+ V A D DS FG+V Y++ + F + ++G + + +DRE++ Y + ATDGGGL + + +++LD NDN P +++ S + V E+ P G+ + IS D D G N+++E++ G+ + N + + LDRE ++++ + D +P RL+S+ +++ + D NDN P P++ +L E +SP V ++++ DPD G N V Y +
Sbjct: 1494 PPMSSFNQVEISVEDVNDNPPVFAVPEMELEVEENTGEGEVIFTLSATDADQGQNALVTYSVLSGSEGAF-VVDAASGVLRASRRLDREERASYLLTVRASDGTHA---TDARLSVAVRDANDNSPRFSRHAYSFDVAEDAAPDGKTTRAVIGTVLAGDADSGPFGEVTYALAPSEDSDWADGAFGLHPVTGALNVTRPLDRESRACYVLRARATDGGGLAATARLYVNVLDANDNAPSVQNDSLAAEVPEDAPPGTSLLRISATDDDEGVNAELEFSISS-GDPEGRFAVGNDGQLSVARALDRERQSFYNLVVRVSDRARHPPARLSSAVRVSLILTDVNDNAPAFTSPRS-ALAPE--------DSPVGAVVATVQAVDPDSGRNSYVEYAL 1874 HSP 9 Score: 125.561 bits (314), Expect = 3.565e-29 Identity = 160/623 (25.68%), Postives = 265/623 (42.54%), Query Frame = 2
Query: 449 KVVIVIEDENDNAPDXXXXXXXXXXXXNDATQLDHNLPKALDKDCPIYGIKNYS-LSGNKVEYFSLKIRQFQPFLSVKKSFDFENPSEKQFNLSLNAIDNGGKSATLQLIVNVIDINDNPPIFQKKIVNVTIQENTTFPDA------ILKLNATDLDSGNNAQISYKFS-SINRPIIRETFQLQSETGKIYLLKTLDYELYSEQNFDINVLAIDHGSPQLSDSCIIKVNVTDINDNSPVIE-IVHSQPIPENEQITDPALKLYVSDYDSIDNDVKCQAEKIGRRLKLEQVEKSSYF-------IYATEIYDYEKEKNLSLSILCQDSGKEP--RYTKQL-LTIFIKDVNDNRPKFLRSFYRKSIN-EDQEKLKPFTKVQALDKDSDDFGKVKYSIGL----------KDRKYFSIDEISGEVRLANEIDRETKDFYNVSVIATDGG--GLKDYSYIEISILDVNDNYPKL-KSGSSMRVNENLPVGSVVGYISVIDLDLGDNSKVEWTYDFL-GNSSSMLQIENC--TVYTSTVLDRESIEHLHILITMVDMGYPRLTSSATITVSVIDENDNIPKV-IYPKTGSLVEEREMDHIAVNSPKYTTVLSIKSFDPDLGINGDVLY 2206
+V I +ED NDN P F+ + + EN A D D + YS LSG++ + + L + D E + L++ A D G + +L V V D NDN P F + + + E+ PD I + A D DSG +++Y + S + F L TG + + + LD E S + + A D G L+ + + VNV D NDN+P ++ + +PE+ L++ +D D V + E + + F + D E++ +L + D + P R + + +++ + DVNDN P F R ++ ED VQA+D DS V+Y++ F+++ ++GEVRL E+DRE + Y ++V+A D G L + + +++ D NDN P+ + + E+ P G+ V +S D D G N E YD G+ + +++ T+ + LDRE + + D G P + +A++ V++ D ND P + P T V RE P +L + + D DLG +G V Y
Sbjct: 1501 QVEISVEDVNDNPPVFAVPEMELEVEENTGEGEVIFTLSATDADQGQNALVTYSVLSGSEGAFV---VDAASGVLRASRRLDREE--RASYLLTVRASD-GTHATDARLSVAVRDANDNSPRFSRHAYSFDVAEDAA-PDGKTTRAVIGTVLAGDADSGPFGEVTYALAPSEDSDWADGAFGLHPVTGALNVTRPLDRE--SRACYVLRARATDGGG--LAATARLYVNVLDANDNAPSVQNDSLAAEVPEDAPPGTSLLRISATDD---DEGVNAELE-----FSISSGDPEGRFAVGNDGQLSVARALDRERQSFYNLVVRVSDRARHPPARLSSAVRVSLILTDVNDNAPAFTSP--RSALAPEDSPVGAVVATVQAVDPDSGRNSYVEYALATDGEEGGGGAGAGPGPFALNTVTGEVRLVRELDREARQSYALTVLAVDKGRPPLTSTATLAVTVGDANDNAPRFPRREYEAAIAEDEPPGTEVLRLSAWDPDEGANG--ELRYDIASGDPTGDFRLDPVLGTLAVARPLDRERTASYELAVRARDGGGPARSDTASVRVTLSDVNDCSPAFQLSPYT---VHAREN----TQGPP-VLILQVVARDDDLGSSGQVTY 2092 HSP 10 Score: 82.4185 bits (202), Expect = 5.785e-16 Identity = 78/300 (26.00%), Postives = 133/300 (44.33%), Query Frame = 2
Query: 1385 KEPRYTKQLLTIFIKDVNDNRPKFLRSFYRKSINEDQEKLKPFTKVQALDKDSDDFGKVKYSIGLKDRKYFSIDEISGEVRLANEIDRETKDFYNVSVIATDGGGLKDYSYIEISILDVNDNYPKL-KSGSSMRVNEN-LPVG----SVVGYISVIDLDLGDNSKVEWTY------DFLGNSSSMLQIENCTVYTSTVLDRESIEHLHILITMVDMGYPRLTSSATITVSVIDENDNIPKVIYPKTGSLVEEREMDHIAVNSPKYTTVLSIKSFDPDLGINGDVLYHILPSNGSQYFIIN 2248
+ P + + I ++DVNDN P F + E+ + + + A D D V YS+ F +D SG +R + +DRE + Y ++V A+DG D + + +++ D NDN P+ + S V E+ P G +V+G + D D G +V + D+ + + + T LDRES + D G L ++A + V+V+D NDN P V + SL E + ++P T++L I + D D G+N ++ + I + F +
Sbjct: 1493 RPPMSSFNQVEISVEDVNDNPPVFAVPEMELEVEENTGEGEVIFTLSATDADQGQNALVTYSVLSGSEGAFVVDAASGVLRASRRLDREERASYLLTVRASDGTHATD-ARLSVAVRDANDNSPRFSRHAYSFDVAEDAAPDGKTTRAVIGTVLAGDADSGPFGEVTYALAPSEDSDWADGAFGLHPVTGALNVTRP-LDRESRACYVLRARATDGGG--LAATARLYVNVLDANDNAPSV---QNDSLAAE-----VPEDAPPGTSLLRISATDDDEGVNAELEFSISSGDPEGRFAVG 1780 HSP 11 Score: 68.5514 bits (166), Expect = 8.248e-12 Identity = 70/237 (29.54%), Postives = 116/237 (48.95%), Query Frame = 2
Query: 452 VVIVIEDENDNAPDXXXXXXXXXXXXNDATQLDHNL--PKALDKDCPIYGIKNYSL-SGNKVEYFSLKIRQFQPFLSVKKSFDFENPSEKQFNLSLNAIDNG--GKSATLQLIVNVIDINDNPPIFQKKIVNVTIQENTTFPDAILKLNATDLDSGNNAQISYKFSSINRPIIRETFQLQSETGKIYLLKTLDYELYSEQNFDINVLAIDHGSPQLSDSCIIK---VNVTDINDNSP 1138
V + + DENDN P F+ES ++ ++T++ L A D+D G Y++ +GN F++ FL+ + DFE +++ + L+++A D G +S+ L+V+V D NDNPP F V +I EN ++ + A D D+ N ++ Y + P F + E+G+I +D E+ F++ V A D P + +K V VTD NDN+P
Sbjct: 1063 VAVQVLDENDNPPRFTESLLSVDAL--ESTRVGELLITLTASDEDTGPSGDVRYAIVAGNTHATFAIDRSTGSVFLA--RRLDFE--TQRLYRLNVSAEDGGRPPRSSATILVVHVRDFNDNPPAFLPGDVFASIMENIPIGTRVITVTARDPDADVNGELHYSIARQFPPGAH--FTIDPESGEICTAAEIDREVTGGL-FEVTVRATDKAIPVHTRRSALKNVTVLVTDENDNAP 1290
BLAST of Protocadherin alpha-2 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000006996.1 (pep scaffold:Pmarinus_7.0:GL476780:2096:143714:1 gene:ENSPMAG00000006222.1 transcript:ENSPMAT00000006996.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 171.014 bits (432), Expect = 4.148e-43 Identity = 173/634 (27.29%), Postives = 288/634 (45.43%), Query Frame = 2
Query: 446 VKVVIVIEDENDNAPDXXXXXXXXXXXXNDATQLDHNLPKALDKDCPIYGIKNYSLSGNKVEYFSLKIRQFQPFLSVKKSFDFENPSEKQFNLSLNAIDNGGKSATLQLIVNVIDINDNPPIFQKKIVNVTIQENTTFPDAILKLNATDLDSGNNAQISYKFSSINRPIIRETFQLQSETGKIYLLKTLDYELYSEQNFDINVLAIDHGSPQLSDSCIIKVNVTDINDNSPVIEI-VHSQPIPENEQITDPALKLYVSDYDSIDNDVKCQAEKIGRRLKLEQVEKSSYF--------IYATEIYDYEKEKNLSLSILCQDSGKEPRYTKQLLTIFIK--DVNDNRPKFLRSFYRKSINEDQEKLKPFTKVQALDKDSDDFGKVKYSIGLKDRKYFSIDEISGEVRLAN-EIDRET------KDFYNVSVIATDGGG----LKDYSYIEISILDVNDNYPKLKSGS-SMRVNENLPVGSVVGYISVIDLDLGDNSKVEWTYD-FLGNSSSMLQIENCTVYTSTVLDRESIEHLHILITMVDMGYPRLTSSATITVSVIDENDNIPKVIYPKTG-SLVEEREMDHIAVNSPKYTTVLSIKSFDPDLGINGDVLYHILPSNGSQYFIINQTSGVLKT 2272
+V I + +ENDN P FS + +S++EN A D D ++G +Y S + + FSL +SV + DFE + +F +++ A D GG+ ++ +N++D+NDN P+FQ+ T +EN ++++ ATD DS N QI+Y + + + G + L + LDYE + ++A+D GSP L+ + V V D NDNSP+ + +S IPEN I A LYV ++ D D Q+ + G+ + +E S+ F I +T + D E L + D G + T+ I DVNDN P + Y +I E+ V A D D ++ G + Y+I + ++ I+ SG++R ++DRE ++ V D G + + + + DVNDN P +++V E LP S + ++ D D G N V ++ L L + T LDRE++ + + D G P L+S+ T+++ V+D NDN P ++ SL+E D + V+S+ D D G+N ++ + I N F + G+++T
Sbjct: 14 ARVHITLINENDNRPIFSLPLYNVSVWENATLGTSVVQVLATDLDAGVFGQVSYHFSDDS-DKFSLD--PASGLISVAAALDFE--ATPRFTVTVMARDGGGQETAGRVRINLLDVNDNTPVFQRDSYVGTARENDNSLTPVVRVRATDEDSPPNNQITYSILPTSAYSSYFSITVSGGYGVVTLARALDYEKIPGGTISLTIMALDGGSPPLNSTVTAIVEVFDENDNSPIFDRNSYSIAIPEN--ILAGATVLYV---NATDGD---QSPEYGQLSLIYSLEGSTQFRINARSGDITSTTLLDREAVSQYILIVRAVDGGDGNDQKTGIATVNITLLDVNDNDPAWRDLPYAVTIVENTPGGTDIFTVSAADPDLNENGTLVYAIDPPN-PFYRINAASGKIRTTGLQLDREDLNPISFASMRSIVVSGADRGSPPRRATASATVTVLLQDVNDNEPSFVGLPYALQVLEGLPANSTLFQVTATDPDEGANGNVTYSMTAALPRPDFQLDAATGLITTLVQLDREAVAAYQLRLVATDRGTPALSSTTTLSLVVLDVNDNAPTFHPARSAVSLMESVARDSV---------VISLNCTDADSGLNAELSFFITGGNQDGQFSVGFRDGLVRT 624 HSP 2 Score: 162.925 bits (411), Expect = 1.378e-40 Identity = 175/632 (27.69%), Postives = 284/632 (44.94%), Query Frame = 2
Query: 449 KVVIVIEDENDNAPDXXXXXXXXXXXXNDATQLDHNLPKALDKDCPIYGIKNYSL--SGNKVEYFSLKIRQFQPFLSVKKSFDFENPSEKQFNLSLNAIDNGGK--SATLQLIVNVIDINDNPPIFQKKIVNVTIQENTTFPDAILKLNATDLD-SGNNAQISYKFSSINRPIIRETFQLQSETGKIYLLKTLDYELYSEQNFDINVLAIDHGSPQLSDSCIIKVNVT--DINDNSPVI-EIVHSQPIPENEQITDPALKLYVSDYDSIDNDVKCQAEKIGRRLKLEQVEKSSYFIYATEI-YDYEKEKNLSLS------ILCQDSGKEPRYT--KQLLTIFIKDVNDNRPKFLRSFYRKSINEDQEKLKPFTKVQALDKDSDDFGKVKYSI-GLKDRKYFSIDEISGEVRLANEIDRETKDFYNVSVIATDGG--GLKDYSYIEISILDVNDNYPKLKSG-SSMRVNENLPVGSVVGYISVIDLDLGDNSKVEWTYDFLGNSSSMLQI--ENCTVYTSTVLDRESIEHLHILITMVDMGYP--RLTSSATITVSVIDENDNIPKVIYPKTGSLVEEREMDHIAVNSPKYTTVLSIKSFDPDLGINGDVLYHILPSNGSQYFIINQTSGVLK 2269
+V I + D NDN P F S+ + END + +A D+D P YS+ + YFS+ + +++ ++ D+E +L++ A+D G ++T+ IV V D NDN PIF + ++ I EN +L +NATD D S Q+S +S F++ + +G I LD E S+ + + V A+D G + I VN+T D+NDN P ++ ++ I EN + +D D +N A I ++ +S I T + D E +S + + D G PR +T+ ++DVNDN P F+ Y + E +V A D D G V YS+ R F +D +G + ++DRE Y + ++ATD G L + + + +LDVNDN P S++ + E++ SVV ++ D D G N+++ + + GN + + V T LDRE+ ++I +D G R T + T+ V V+D NDN P + V E N + +L +++ D D GING V Y I+ N F++N +SG++
Sbjct: 116 RVRINLLDVNDNTPVFQRDSYVGTARENDNSLTPVVRVRATDEDSPPNNQITYSILPTSAYSSYFSITVSGGYGVVTLARALDYEKIPGGTISLTIMALDGGSPPLNSTVTAIVEVFDENDNSPIFDRNSYSIAIPENILAGATVLYVNATDGDQSPEYGQLSLIYSLEGS----TQFRINARSGDITSTTLLDREAVSQ--YILIVRAVDGGDGNDQKTGIATVNITLLDVNDNDPAWRDLPYAVTIVENTPGGTDIFTVSAADPDLNENGTLVYA--IDPPNPFYRINAASGKIRTTGLQLDREDLNPISFASMRSIVVSGADRGSPPRRATASATVTVLLQDVNDNEPSFVGLPYALQVLEGLPANSTLFQVTATDPDEGANGNVTYSMTAALPRPDFQLDAATGLITTLVQLDREAVAAYQLRLVATDRGTPALSSTTTLSLVVLDVNDNAPTFHPARSAVSLMESVARDSVVISLNCTDADSGLNAELSF-FITGGNQDGQFSVGFRDGLVRTVVSLDRETKASYSLVIEAIDNGPAGSRRTGTTTLDVLVLDVNDNRPLFLEGSYEVSVPE--------NVTRGAIILQVQATDIDEGINGRVWYRIISGNQDGNFLVNVSSGLIS 730 HSP 3 Score: 134.42 bits (337), Expect = 8.025e-32 Identity = 144/542 (26.57%), Postives = 245/542 (45.20%), Query Frame = 2
Query: 758 ATLQLIVNVIDINDNPPIFQKKIVNVTIQEN-TTFPDAILKLNATDLDSGNNAQISYKFSSINRPIIRETFQLQSETGKIYLLKTLDYELYSEQNFDINVLAIDHG---SPQLSDSCIIKVNVTDINDNSPVIEIVHSQPIPENEQITDPALKLYV-SDYDS----------IDNDVKCQAEKIGRRLKLEQVEKSSYFIYATEIYDYEKEKNLSLSILCQDSGKEPRYTKQLLTIFIKDVNDNRPKFLRSFYRKSINEDQEKLKPFTKVQALDKDSDD-----FGKVKYSIGLKDRKYFSIDEISGEVRLANEIDRETKDFYNVSVIATDGG-----GLKDYSYIEISILDVNDNYPKLKSGS-SMRVNENLPVGSVV----GYISVIDLDLGDNSKVEWTYDFLGNSSSMLQIE----NCTVYTSTVLDRESIEHLHILITMVDMGYPRLTSSATITVSVIDENDNIPKVIYPKTGSLVEEREMDHIAVNSPKY-TTVLSIKSFDPDLGI--NGDVLYHILPSNGSQYFIINQTSGVLKT 2272
AT +++ + D NDN P F V + E +T A+ + A+D D G+NA++ Y S N TF + + TG + +K LD+E+ S + + V A D + +L+ + + V+V D+ND +P + PI +E P + ++ SD DS ID D + + + + E+ D E + +L+I+ +D G P + + + + DV+DN P FL S++E L ++V+A D + S +R +++ D +G V + +DRE Y +++ D KD + ++ILD NDN P + + EN P G+V+ G I D D G N+ + Y LG SS+ I+ N ++ LDRE I + +T++ R ++ + V+V+D NDN P + + H+ NSP T+V+ +K+ D DLG+ G V Y I S G+ F I++++G++ T
Sbjct: 1154 ATTSVLIRITDENDNAPAFGAATYEVLLTEGPSTAGVAVANVTASDPDEGDNARVVYAIVSGN---TAATFGIDNGTGVLTAVKALDFEV-SAGLYLLVVTATDQPRDPARRLTSTATVSVHVADVNDVTPWFLRSYEGPIDVSEGQPGPRIATFMASDQDSGLNGELEYSIIDGDPRNE-------FVISPADGDLRVRRYVEL-DRETQAFYNLTIMAKDMGTPPLNSTLTVGVRVLDVHDNDPVFLNLPANASLSEAAAVLAIVSRVRASDANEGRNCAALLQHSPTSFCNGERAFYA-DSQTGLVYVNRPLDRERVAEYRLTLTVRDNPDNPSYARKDSDIMIVTILDENDNSPVFSQVTYEAEIPENSPNGTVLTVLNGPIYASDADFGVNATL--AYSLLGGSSAYFLIDRDRGNVSMALGQGLDREGIPGGRLELTILVQDGGRRNATVRLGVTVLDVNDNTP--------TFNVTSQTAHVLENSPAVGTSVIVVKAMDRDLGVCDAGTVRYSIA-SGGNDTFGIDESTGLIVT 1671 HSP 4 Score: 130.183 bits (326), Expect = 1.400e-30 Identity = 155/642 (24.14%), Postives = 283/642 (44.08%), Query Frame = 2
Query: 452 VVIVIEDENDNAPDXXXXXXXXXXXXNDA---TQLDHNLPKALDKDCPIYGI---KNYSLSGNKVEYFSLKIRQFQPFLSVK--KSFDFENPSEKQFNLSLNAIDNGG--KSATLQLIVNVIDINDNPPIF-QKKIVNVTIQENTTFPDAILKLNATDLDSGNNAQISYKFSSINRPIIRETFQLQSETGKIYLLKTLDYELYSEQNFDINVLAIDHGSPQLSDSCIIKVNVTDINDNSPVIEIVHSQPIPENEQITDPALKLYVSDYDSIDNDVKCQAEKIGRRLKLEQVEKSSYFIYATE--------IYDYEKEKNLSLSILCQDSGKEPRYTKQLLTIFIKDVNDNRPKFLRSFYRKSIN--EDQEKLKPFTKVQALDKDSDDFGKVKYS------IGLKDRKYFSIDEISGEVRLANEIDRETKDFYNVSVIATDGGGLKDYSY---IEISILDVNDNYP---KLKSGS----SMRVNENLPVGSVVGYIS-VIDLDLGDNSKVEWTYDFLGNSSSMLQIENCTVYTS-TVLDRESIEHLHILITMVDMGYPRLTSSAT---------------ITVSVIDENDNIPKVIYPKTGSLVEEREMDHIAVNSPKYTTVLSIKSFDPDLGINGDVLYHIL 2215
V + + DENDN+P+F S T+ A T L + A D+D G + ++ +G ++ + I Q + +++ DF + + + A+D G +S T L V V+D+NDN PIF V++ E + + ATD D+G N Q++++ S + + G I + + + + + + V+A+D G+P LS S I++V V D+ND P P+ + ++ +V+ + +N + K+ + K+++ ++AT + YE+ +L+ + D G+ P + + L + + DVND+RP F+ +N E + +V A+D D G V+YS +G +D + F I+ SG + A +DRE++ Y++ ++A+D G Y +++ + D++DN P L G S + E+ P G+ VG +S +D D+G N+ V + + GN + + + + LDRE + I++ P T + T + V + D ND P +AV++ + +L +++ D D+G N VLY IL
Sbjct: 1825 VYVNVTDENDNSPEFEAGSATLVEVRESAAPGTLL--TVLHATDRDAGSNGTVSARAHTHTGTRIPPQYILIIQNESGVTIVDVAKADFVEKTSQFILFRIVALDGGSPPRSTTFNLSVIVLDVNDNVPIFLSPGGYAVSVVELGAPGTLVASVWATDADAGPNGQVTFRIESGGG----DKLSIGPSDGIIRVAPGANIDRETRAAYTLMVVAVDRGNPPLSGSAIVRVLVDDVNDERPAFL----APVQTVSVLESLSVGSFVATVKATEN---YKGHNTKYTYKIAGIGKNAFTVHATSGLVTSTRLLKSYER---FNLTAVATDHGRPPLWGQAGLYVEVLDVNDHRPVFVLPPNGTVVNITEVMPVVIRIVEVLAVDGDEGQNGAVRYSFLHAGGVGSRDWESFRINATSGIISTARALDRESQAVYSLILLASDQGQPVSYESTQPLQVVLDDIDDNEPVFIVLPDGGAPYQSFSIPEHSPPGTAVGNVSGAVDADVGANAIVYY-FIAAGNEGNKFNLSRWGLLVVLSDLDREVSPYYAIIVKA--SSNPNWTPAVTTGPEFDPSKDRTLREVRVYLEDINDQWPV--------FTNHEYTAGVAVDAKVGSELLQLEAVDRDVGNNSIVLYRIL 2439 HSP 5 Score: 122.479 bits (306), Expect = 3.260e-28 Identity = 152/592 (25.68%), Postives = 251/592 (42.40%), Query Frame = 2
Query: 407 IIVTVIPKNERIPVKVVIVIEDENDNAPDXXXXXXXXXXXXNDATQ------LDHNLPKALDKDCPIYGIKNYSLSGNKVEYFSLKIRQFQPFLSVKKSFDFENPSEKQFNLSLNAIDNGGKSA-----TLQLIVNVIDINDNPPIFQKKIVN-VTIQENTTFPDAILKLNATDLDSGNNAQISYKFSSINRPIIRETFQLQSETGKIYLLKTLDYELYSEQNFDINVLAIDHGSPQLSDSCIIKVNVTDINDNSPVIEIVHSQPIPENEQITDPALKLYVSDYDSIDNDVKCQAEKIGRRL-KLEQVEKSSY--------------FIYATEIYDYEKEKNLSLSILCQDSGKEPRYTKQ---LLTIFIKDVNDNRPKFLRSFYRKSINEDQEKLKPFTKVQALDKDSD-DFG---KVKYSIGLKDRKYFSIDEISGEVRLA--NEIDRET--KDFYNVSVIATDGGGLKDYSYIEISILDVNDNYPKLK-SGSSMRVNENLP-VGSVVGYISVIDLDLG--DNSKVEWTYDFLGNSSSMLQIENCTVYTSTVLDRESIEHLHILITMVDMGYPRLTSSATITVSVIDEND 2056
I +T P V+I I DENDNAP F +++ + + E +T + + P D +Y I +SGN F I L+ K+ DFE S + L + A D A T + V+V D+ND P F + + + E P I A+D DSG N ++ Y SI R F + G + + + ++ + ++ +++ ++A D G+P L+ + + V V D++DN PV +P N +++ A L +I + V+ GR L Q +S+ +Y D E+ L++ +D+ P Y ++ ++ + I D NDN P F + Y I E+ T + SD DFG + YS+ YF ID G V +A +DRE ++++ DGG + +++LDVNDN P + + V EN P VG+ V + +D DLG D V ++ GN + + + T +D E+ +++ D P T+S + VS+ +E D
Sbjct: 1145 ICLTATPAQAT--TSVLIRITDENDNAPAFGAATYEVLLTEGPSTAGVAVANVTASDPDEGDNARVVYAI----VSGNTAATFG--IDNGTGVLTAVKALDFEV-SAGLYLLVVTATDQPRDPARRLTSTATVSVHVADVNDVTPWFLRSYEGPIDVSEGQPGPR-IATFMASDQDSGLNGELEY---SIIDGDPRNEFVISPADGDLRVRRYVELDRETQAFYNLTIMAKDMGTPPLNSTLTVGVRVLDVHDNDPVF-----LNLPANASLSEAAAVL------AIVSRVRASDANEGRNCAALLQHSPTSFCNGERAFYADSQTGLVYVNRPLDRERVAEYRLTLTVRDNPDNPSYARKDSDIMIVTILDENDNSPVFSQVTYEAEIPENSPNGTVLTVLNGPIYASDADFGVNATLAYSLLGGSSAYFLIDRDRGNVSMALGQGLDREGIPGGRLELTILVQDGGRRNATVRLGVTVLDVNDNTPTFNVTSQTAHVLENSPAVGTSVIVVKAMDRDLGVCDAGTVRYSIASGGNDTFGIDESTGLIVTVAPIDYETRPEYLLMVVATDQAPPFHTASCELRVSLQNELD 1712 HSP 6 Score: 117.472 bits (293), Expect = 9.821e-27 Identity = 158/659 (23.98%), Postives = 279/659 (42.34%), Query Frame = 2
Query: 452 VVIVIEDENDNAPDXXXXXXXXXXXXN--DATQLD-HNLP-KALDKDCPIYGIKNYSLSGNKVEYFSLKIRQFQPFLSVKKSFDFENPSEKQFNLSLNAIDNGGKSATLQLIVNVIDINDNPPIFQKKIVNVTIQENT-TFPDAILKLNATDLDSG--NNAQISYKFSSINRPIIRETFQLQSETGKIYLLKTLDYELYSEQNFDINVLAIDHGSPQLSDSCIIKVNVTDINDNSPVIEIVHSQ------PIPENEQITDPALKLYVSDYDSIDNDVKCQAEKIGRRLKLEQVEKSSYF------IYATEIYDYEKEKNLSLSILCQDSGKEPRYTKQLLT--------IFIKDVNDNRPKFLRSFYRKSINEDQEKLKP---FTKVQALDKDSDDFGKV--------------KYSIGLKDRKYFSIDEISGEVRLANEIDRETKDFYNVSVIATDGGGLKDYSYIEIS--ILDVNDNYPKLKS--GSSMRVNENLPVGSVVGYISVIDLDLGDNSKVEWTYDFLGNSSSMLQIENCTVYTS--TVLDRESIEHLHILITMVDMGYPRLTSSATITVSVIDENDNIPKVIYP-KTGSLVEEREMDHIAVNSPKYTTVLSIKSFDPDLGINGDVLYHILPSNGSQYFIINQTSGVLKTT 2275
+++ I DENDN+P FS+ ++ I EN + T L N P A D D + YSL G YF + + +++ + D E + L++ D G ++AT++L V V+D+NDN P F + EN+ +++ + A D D G + + Y +S +TF + TG I + +DYE E + + V+A D P + SC ++V++ + D + Q +P + A ++ + + Q +R K ++ + + I D E + L++L +D G PR +LT + + D NDN P+F ++ E +E P T + A D+D+ G V +Y + +++ +I +++ + +T F ++A DGG + +S +LDVNDN P S G ++ V E G++V + D D G N +V + + G + + + + +DRE+ +++ VD G P L+ SA + V V D ND P + P +T S++E + V ++K+ + G N Y I G F ++ TSG++ +T
Sbjct: 1486 MIVTILDENDNSPVFSQVTYEAEIPENSPNGTVLTVLNGPIYASDADFGVNATLAYSLLGGSSAYFLIDRDRGNVSMALGQGLDREGIPGGRLELTILVQDGGRRNATVRLGVTVLDVNDNTPTFNVTSQTAHVLENSPAVGTSVIVVKAMDRDLGVCDAGTVRYSIASGG----NDTFGIDESTGLIVTVAPIDYETRPE--YLLMVVATDQAPPFHTASCELRVSLQNELDEKLSFSLAAYQAALSEAAVPGTVVVRVAAPQMKAPPKLPLPLAILVQKWHEDKRHKQQESDNAELIAALQGEITTQAALDREATDSYMLTVLSRDGG--PREAIAVLTNKPGAYVYVNVTDENDNSPEF--EAGSATLVEVRESAAPGTLLTVLHATDRDAGSNGTVSARAHTHTGTRIPPQYILIIQNESGVTIVDVAKA-----DFVEKTSQFILFRIVALDGGSPPRSTTFNLSVIVLDVNDNVPIFLSPGGYAVSVVELGAPGTLVASVWATDADAGPNGQVTFRIESGGGDKLSIGPSDGIIRVAPGANIDRETRAAYTLMVVAVDRGNPPLSGSAIVRVLVDDVNDERPAFLAPVQTVSVLESLSVGSF---------VATVKATENYKGHNTKYTYKIA-GIGKNAFTVHATSGLVTST 2119 HSP 7 Score: 108.612 bits (270), Expect = 5.664e-24 Identity = 146/542 (26.94%), Postives = 236/542 (43.54%), Query Frame = 2
Query: 446 VKVVIVIEDENDNAPDXXXXXXXXXXXXN---DATQLDHNLPKALDKD-CPIYGIKN--YSLSGNKVEYFSLKIRQFQPFLSVKKSFDFENPSEKQFNLSLNAIDNGG----KSATLQLIVNVIDINDNPPIFQKKIVNVTIQENTTFPDAILKLNATDLDSGNNAQISYKFSSINRPIIRETFQLQSETGKIYLLK-TLDYELYSEQNF----DINVLAIDHGSP--QLSDSCIIKVNVTDINDNSP-VIEIVHSQPIPENEQITDPALKLYVSDYDSIDNDVKCQAEKIGRRLKLEQVEKSSYFIYATEIYDYEKEKNLSLSILCQDSGKEPRYTKQLLTIFIKDVNDNRPKFLRSFYRKSINEDQEKLKPFTKVQALDKDSDDFGKVKYSI-GLKDRKYFSIDEISGEVRLANEIDRETKDFYNVSVIATDGGGLKDY----SYIEISILDVNDNYPKLKSGS-SMRVNENLPVGSVVGYISVIDLDLGDNSKVEWTY-------DFLGNSSSMLQIENCTVYTSTVLDRESIEHLHIL 1978
V ++ + DENDN+P F +S++I+I EN AT L N A D D P YG + YSL G+ F + R + + + + Q+ L + A+D G K+ + + ++D+NDN P ++ VTI ENT I ++A D D N + Y N P +++ + +GKI LD E + +F I V D GSP + + S + V + D+NDN P + + ++ + E ++ +D D N + Q++ ++ I D E L ++ D G + L++ + DVNDN P F + S+ E + + D DS ++ + I G FS+ G VR +DRETK Y++ + A D G + +++ +LDVNDN P GS + V EN+ G+++ + D+D G N +V + +FL N SS L +T LDRE++ LH L
Sbjct: 225 VTAIVEVFDENDNSPIFDRNSYSIAIPENILAGATVLYVN---ATDGDQSPEYGQLSLIYSLEGST--QFRINARSGD----ITSTTLLDREAVSQYILIVRAVDGGDGNDQKTGIATVNITLLDVNDNDPAWRDLPYAVTIVENTPGGTDIFTVSAADPDLNENGTLVYAIDPPN-PF----YRINAASGKIRTTGLQLDREDLNPISFASMRSIVVSGADRGSPPRRATASATVTVLLQDVNDNEPSFVGLPYALQVLEGLPANSTLFQVTATDPDEGANGNVTYSMTAALPRPDFQLDAATGLITTLVQLDREAVAAYQLRLVATDRGTPALSSTTTLSLVVLDVNDNAPTFHPARSAVSLMESVARDSVVISLNCTDADSGLNAELSFFITGGNQDGQFSVGFRDGLVRTVVSLDRETKASYSLVIEAIDNGPAGSRRTGTTTLDVLVLDVNDNRPLFLEGSYEVSVPENVTRGAIILQVQATDIDEGINGRVWYRIISGNQDGNFLVNVSSGLISRG-----ATPLDRETVA-LHAL 746 HSP 8 Score: 104.76 bits (260), Expect = 8.489e-23 Identity = 135/587 (23.00%), Postives = 247/587 (42.08%), Query Frame = 2
Query: 674 VKKSFDFENPSEKQFNLSLNAIDNGGKSATLQ-----LIVNVIDINDNPPIFQKKIVNVTIQENTTFPDAILKLN----ATDLDSGNNAQISYKFSSINRPIIRETFQLQSETGKI--YLLKTLDYELYSEQNFDINVLAIDHGSPQLSDSCIIKVNVTDINDNSPVIEIV-HSQPIPENEQITDPALKLYVSDYDSIDNDVK-CQAEKIGRRLKLEQ-------VEKSSYFIYATEIYDYEKEKNLSLSILCQDSGKEPRYTKQLLTIFIKDVNDNRPKFLRSFYRKSINEDQEKLKPFTKVQALDKDSDDFGKVKYSIGLKDRKYFS--------------IDEISGEVRLANEIDRETKDFYNVSVIATDGGGL--------KDYSYIEISILDVNDNYPKLKSGSS--MRVNENLPVGSVVGYISVIDLDLGDNSKVEW-TYDFLGNS---SSMLQIENCTVYTSTVLD-------RESIEHLHILITMVDMGYPRLTSSATITVSVIDENDNIPKVIYPKTGSLVEEREMDHIAVNSPKYTTVLSIKSFDPDLGINGDVLYHILPSNGSQYFIINQTSGVLK 2269
V + D E +E + L+L DN + + +IV ++D NDN P+F + I EN+ + LN A+D D G NA ++Y + F + + G + L + LD E ++ +L D G + + + + V V D+NDN+P + + + EN PA+ V ++D D+ C A + R + +++S+ I DYE L ++ D L + +++ D + F + Y+ +++E +V A + K+ + + +K+ I + GE+ +DRE D Y ++V++ DGG K +Y+ +++ D NDN P+ ++GS+ + V E+ G+++ + D D G N V + G +L I+N + T++D ++ + + I +D G P +++ ++V V+D NDN+P + P G V E+ +P T V S+ + D D G NG V + I S G I + G+++
Sbjct: 1451 VNRPLDRERVAE--YRLTLTVRDNPDNPSYARKDSDIMIVTILDENDNSPVFSQVTYEAEIPENSPNGTVLTVLNGPIYASDADFGVNATLAYSLLGGSSAY----FLIDRDRGNVSMALGQGLDREGIPGGRLELTILVQDGG--RRNATVRLGVTVLDVNDNTPTFNVTSQTAHVLENS----PAVGTSVIVVKAMDRDLGVCDAGTV--RYSIASGGNDTFGIDESTGLIVTVAPIDYETRPEYLLMVVATDQAPPFHTASCELRVSLQNELDEKLSFSLAAYQAALSEAAVPGTVVVRVAAPQMKAPP--KLPLPLAILVQKWHEDKRHKQQESDNAELIAALQGEITTQAALDREATDSYMLTVLSRDGGPREAIAVLTNKPGAYVYVNVTDENDNSPEFEAGSATLVEVRESAAPGTLLTVLHATDRDAGSNGTVSARAHTHTGTRIPPQYILIIQNES--GVTIVDVAKADFVEKTSQFILFRIVALDGGSPPRSTTFNLSVIVLDVNDNVPIFLSPG-GYAVSVVEL-----GAPG-TLVASVWATDADAGPNGQVTFRI-ESGGGDKLSIGPSDGIIR 2011 HSP 9 Score: 101.293 bits (251), Expect = 9.218e-22 Identity = 93/319 (29.15%), Postives = 141/319 (44.20%), Query Frame = 2
Query: 752 KSATLQLIVNVI--DINDNPPIFQKKIVNVTIQENTTFPDAILKLNATDLDSGNNAQISYKFSSINRPIIRETFQLQSETGKIYLLKTLDYELYSEQNFDINVLAIDHGSPQLSDSCIIKVNVTDINDNSPVIEIVHSQ-PIPENEQITDPALKLYVSDYDSIDNDVKCQAEKIGRRLKLEQVEKSSYFIYATEIYDYEKEKNLSLSILCQDSGKEP--RYTKQLLTIFIKDVNDNRPKFLRSFYRKSINEDQEKLKPFTKVQALDKDSDDFGKVKYSI--GLKDRKYFSIDEISGEV-RLANEIDRETKDFYNVSVIA 1684
+ AT V V+ D+NDN P F + + E + ++ ATD D G N ++Y S+ + R FQL + TG I L LD E + + + ++A D G+P LS + + + V D+NDN+P S + E+ + L +D DS N G + V + D E + + SL I D+G R L + + DVNDNRP FL Y S+ E+ + +VQA D D G+V Y I G +D + ++ SG + R A +DRET + + V A
Sbjct: 438 RRATASATVTVLLQDVNDNEPSFVGLPYALQVLEGLPANSTLFQVTATDPDEGANGNVTY---SMTAALPRPDFQLDAATGLITTLVQLDREAVAA--YQLRLVATDRGTPALSSTTTLSLVVLDVNDNAPTFHPARSAVSLMESVARDSVVISLNCTDADSGLNAELSFFITGGNQDGQFSVGFRDGLVRTVVSLDRETKASYSLVIEAIDNGPAGSRRTGTTTLDVLVLDVNDNRPLFLEGSYEVSVPENVTRGAIILQVQATDIDEGINGRVWYRIISGNQDGNFL-VNVSSGLISRGATPLDRETVALHALQVEA 750 HSP 10 Score: 62.7734 bits (151), Expect = 5.562e-10 Identity = 83/310 (26.77%), Postives = 127/310 (40.97%), Query Frame = 2
Query: 1391 PRYTKQLLTIFIKDVNDNRPKFLRSFYRKSINEDQEKLK-PFTKVQALDKDSDDFGKVKYSI-GLKDRKYFSIDEISGEVRLANEIDRE-TKDFYNVSVIATD-----GGGLKDYSYIEISILDVNDNYPK-LKS-GSSMRVNENLPVGSVVGYISVIDLDLGDNSKVEWTYDFLGNSSSMLQIE----NCTVYTSTVLDRESIEHLHILITMVDMGYPRLTSSATITVSVIDENDNIPKVI-YPKTGSLVEEREMDHIAVNSPKYTTVLSIKSFDPDLGINGDVLYHILPS---NGSQYFIINQTSGVL 2266
P + I I D NDN P F + Y + E V A D D D +V Y+I F ID +G + +D E + Y + V ATD L + + + + DVND P L+S + V+E P G + D D G N ++E++ G+ + I + V LDRE+ ++ I DMG P L S+ T+ V V+D +DN P + P SL E + I V +++ D + G N L P+ NG + F + +G++
Sbjct: 1151 PAQATTSVLIRITDENDNAPAFGAATYEVLLTEGPSTAGVAVANVTASDPDEGDNARVVYAIVSGNTAATFGIDNGTGVLTAVKALDFEVSAGLYLLVVTATDQPRDPARRLTSTATVSVHVADVNDVTPWFLRSYEGPIDVSEGQP-GPRIATFMASDQDSGLNGELEYSI-IDGDPRNEFVISPADGDLRVRRYVELDRETQAFYNLTIMAKDMGTPPLNSTLTVGVRVLDVHDNDPVFLNLPANASLSEAAAVLAI---------VSRVRASDANEGRNCAALLQHSPTSFCNGERAFYADSQTGLV 1449
BLAST of Protocadherin alpha-2 vs. Ensembl Nematostella
Match: EDO40470 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S751]) HSP 1 Score: 234.572 bits (597), Expect = 1.074e-62 Identity = 209/661 (31.62%), Postives = 332/661 (50.23%), Query Frame = 2
Query: 350 NVCGPLGCCDKPSCEIVLDIIVTVIPKNERIP-----VKVVIVIEDENDNAPDXXXXXXXXXXXXNDATQLDHNL--PKALDKDCPIYGIKNYSLSGNKVEYFSLKIRQFQPFLSVKKSFDFENPSEKQFNLSLNAIDNGG--KSATLQLIVNVIDINDNPPIFQKKIVNVTIQENTTFPDA-ILKLNATDLDSGNNAQISYKFSSINRPIIRETFQLQSETGKIYLLKTLDYELYSEQNFDINVLAIDHGSPQLSDSCIIKVNVTDINDNSPVIEIV-HSQPIPENEQITDPALKLYVSDYDSIDNDVKCQAEKIGRRLKLEQVEKSSYFIYATEIYDYEKEKNLSLSILCQDSGKEPRYTKQLLTIFIKDVNDNRPKFLRSFYRKSINEDQEKLKPFTKVQALDKDSDDFGK-VKYSIGLKDRKYFSIDEISGEVRLANEIDRETKDFYNVSVIATDGGG---LKDYSYIEISILDVNDNYPKLKSGSSMR-VNENLPVGSVVGYISVIDLDLGDNSKVEWTYDFLGNSSSMLQIENCTVYTSTV--LDRESIEHLHILITMVDMGYPRL-TSSATITVSVIDENDNIPKVIYPKTGSLVEEREMDHIAVNSPKYTTVLSIKSFDPDLGINGDVLYHILPSNGSQYFIINQTSGVLKTT 2275
N G L + E + + +TV K++ P V I + D NDN+P F+ SS + + E+ T + H D D + G ++SL N F+L LS+ K D+ N S + + L + A D G +S+T L + V+D+ND P+F + E TT PD+ I+++ ATD+DSG N +ISY F S + F L++ GKI++ LD E E +++ V+AIDHG+P+ S S +KV V D+NDN+P + ++ + ENE + + SD D N + ++ V+K + I +++ D E + + SI+ D G PR K +T+ ++DVND PKF ++ Y ++NED + A D D + Y I + K FS+++++G + L + +DRE + + V+A+D GG L+ +YIEI++LDVNDNYP + ++ + V E LP+GSVV + +D D GDN KV + GN+ +I T ST+ LD E + ++ DMG + TS +T+ V D NDN P + + + I N P T V +IK+ D D G+N + Y I + +F IN +G+++TT
Sbjct: 754 NSTGTLYLQSEVDHEKIPSLYLTVQAKDKGTPPLFGYANVTIAVIDINDNSPQFNSSSILVRLPED--TPIGHTFYTVSVFDADSGVLGRVSFSLLSNPGTLFNLDSNTGA--LSLTKLIDYGN-SARSYTLPVQAQDGGSPPRSSTAMLELKVVDVNDYSPVFGNWSYTAHVLE-TTPPDSNIIEVVATDVDSGENGRISYAFDS---KVDTSKFGLRNG-GKIFIKSKLDREDIEE--YNLKVIAIDHGTPRRSSSADVKVIVDDVNDNNPHFQQASYAFFVKENEPVATYLGAVSASDSDEGSN--GHVTYRFDTQVAQFIVDKQTGKITTSQVLDREAKASYVFSIVATDGGSSPRVDKTQVTVIVRDVNDCSPKFSKNKYSVTVNEDLPVGSSLLTLIATDDDQQGPNSDITYMI-VAGPKAFSLNQVTGVLTLVSPLDREVTHRHILHVVASDKGGNQSLETITYIEINVLDVNDNYPVFINETTFKTVPEKLPIGSVVAAVLAVDSDQGDNGKVRYKI-VNGNTDGTFKINETTGVISTLRALDFEVTNRYVLRVSATDMGKKQQKTSYQLVTIYVEDANDNRP--------TFDKNPIITWIYENVPINTNVTTIKAHDDDSGLNSRIWYTIDSQSPRAHFKINSETGLIQTT 1390 HSP 2 Score: 169.088 bits (427), Expect = 2.607e-42 Identity = 156/551 (28.31%), Postives = 253/551 (45.92%), Query Frame = 2
Query: 680 KSFDFENPSEKQFNLSLNAIDNGGKSATLQLIVNVIDINDNPPIFQKKIVNVTIQENTTFPDAILKLNATDLDSGNNAQISYKFSSINRPIIR-----ETFQLQSETGKIYLLKTLDYELYSEQNFDINVLAIDHGSPQLSDSCIIKVNVTDINDNSPVI-EIVHSQPIPENEQITDPALKLYVSDYDSIDNDVKCQAEKI-----GRRLKLEQVEKSSYFIYATEIYDYEKEKNLSLSILCQDSGKEPRYTKQLLTIFIKDVNDNRPKFLRSFYRKSINEDQEKLKPFTKVQALDKDSDDFGKVKYSIGLKDRKYFSIDEISGEVRLANEID-RETKDFYNVSVIATDGGG--LKDYSYIEISILDVNDNYPKLKSGS-SMRVNENLPVGSVVGYISVIDLDLGDNSKVEWTYDFLGNSSSMLQIENCTVYTSTVLDRESIEHLHILITMVDMGYPRLTSSATITVSVIDENDNIPKVIYPKTGSLVEEREMDHIAVNSPKYTTVLSIKSFDPDLGINGDVLYHILPSNGSQYFIINQTSGVLKTTWIYD 2287
++ D E S F ++ A D GG+S + V++ D+NDN P+F +V ENT +I +L A D DS KF+ I R II E F + +G I L K LD E ++ N+ + V A+D G + I+ + V D+ND P+ + ++ I E+ Q AL + + +I D AE + G + + + +E+ D+EK +L L++ +D G P + +TI + D+NDN P+F S + ED F V D DS G+V +S+ F++D +G + L ID + Y + V A DGG + +E+ ++DVND P + S + V E P S + + D+D G+N ++ + +D ++S ++ + LDRE IE ++ + +D G PR +SSA + V V D NDN P V+E N P T + ++ + D D G NG V Y FI+++ +G + T+ + D
Sbjct: 557 RTLDHEVQSSYTFQVA--ATDGGGRSCNATVHVSLTDLNDNQPVFDPSSYSVEYFENTRIGQSICQLKAIDRDSP-------KFA-ITRFIIEQGNADEVFSVDG-SGLITLAKLLDRE--TQDNYLLTVKAVDGGGQDSVNKAIVNITVLDVNDEPPIFSKAEYNFTIQEHSQ----ALSV-IGHVHAISRDKGTNAEVVYSISKGNTDNIVLINSTGTLYLQSEV-DHEKIPSLYLTVQAKDKGTPPLFGYANVTIAVIDINDNSPQFNSSSILVRLPEDTPIGHTFYTVSVFDADSGVLGRVSFSLLSNPGTLFNLDSNTGALSLTKLIDYGNSARSYTLPVQAQDGGSPPRSSTAMLELKVVDVNDYSPVFGNWSYTAHVLETTPPDSNIIEVVATDVDSGENGRISYAFDSKVDTSKFGLRNGGKIFIKSKLDREDIEEYNLKVIAIDHGTPRRSSSADVKVIVDDVNDNNPHFQQASYAFFVKE--------NEPVATYLGAVSASDSDEGSNGHVTYRF--DTQVAQFIVDKQTGKITTSQVLD 1078 HSP 3 Score: 160.999 bits (406), Expect = 9.175e-40 Identity = 159/601 (26.46%), Postives = 270/601 (44.93%), Query Frame = 2
Query: 611 LSGNKVEYFSLKIRQFQPFLSVKKSFDFENPSEKQFNLSLNAIDNGGKSATLQLI--VNVIDINDNPPIFQKKIVNVTIQENTTF--PDAILKLNATDLDSGNNAQISYKFSSINRPIIRETFQLQSETGKIYLLKTLDYELYSEQNFDINVLAIDHGSPQLSDSCIIKVNVTDINDNSPVIEIVHSQPIPENEQITDPALKLYVSDYDS---IDNDVKCQAEKIGRRLKLEQVE---------KSSYFIYATEIYDYE------------------KEKNLSLSILCQDSGKEPRYTKQLLTIFIKDVNDNRPKFLRSFYRKSINEDQEKLKPFTKVQALDKDSD-DFGKVKYSIGLKDRKYFSIDEISGEVRLANEIDRETKDFYNVSVIATDGGG----LKDYSYIEISILDVNDNYPKL-KSGSSMRVNENLPVGSVVGYISVIDLDLGDNSKVEWTYDFLGNSSSMLQIENCT--VYTSTVLDRESIEHLHILITMVDMGYPRLTSSATITVSVIDENDNIPKVIYPKTGSLVEEREMDHIAVNSPKYTTVLSIKSFDPDLGINGDVLYHILPSNGSQYFIINQTSGVLKTTWIYD 2287
+SGNK F + F +SV + + S K F L L A G S +I +NVID NDN P F + + E+T P ++K+ ATD+DSG N +++Y + N + F + S TG+I K LD E + +FD+ + D G P S +C +KV VTD+NDN P+ + + I E+ + + +D D + ++K + L++ + K S+ I ++ DY+ ++ + + + D G P Q ++++ + PKF Y + E+ V+ D + G++ Y+I ++ YF I + SG + + +D ETK + + V A D ++ YI +S DVND P +SG + +E +PVG++V +S D D G N +V W G+ I+ T + T LD E+I+ H+ + D G P + + ++T+ V+D NDN P P + + ++++ +NS Y I + D D G N + + ++ G F+I++ SG L T +D
Sbjct: 2000 ISGNKGRAF--YVDPFTGVISVASADALDYESTKNFRLHLVATPQGWVSLNGYMILDINVIDRNDNSPAFHPSNMLAQLAEDTGAFKPRFVVKVTATDVDSGTNGKVTYSIWTGNEAGV---FTIDSTTGEITTAKLLDRE--TTASFDLVIRGTDSGIPPKSTNCQVKVVVTDLNDNPPLFDPLSEVNIREDTRTGAVVTSVVATDTDKESRLTYNLKSASTPGIAILRVSATDQDSGSNAQIKYSFPITNSDQIDYKIDADTGVISARRTIDVRIRDSFIQIPVQAMDQGVPP----QRALVYVRIIITREPKFELPSYFGKVPENAMMGTSVLTVRVTDNAAGLPLGRISYNI--ENSNYFRIGQRSGVISVNKPLDYETKRRFLLVVSAIDDTAPSKPVRVPVYINVS--DVNDEKPVFGQSGYMAQWSEGIPVGTIVVNVSAADKDSGANGRV-WFAIQSGDDKGSFAIDRKTGVIRTQRALDHETIKTHHVSVRATDEGSPPMHTDVSVTIRVLDLNDNPPVFRVPGPNDV---QVLENLPLNSRLY----EINATDRDSGANARLSFTVIGGTGQGLFLIDKFSGWLTTNITFD 2577 HSP 4 Score: 158.688 bits (400), Expect = 4.556e-39 Identity = 164/563 (29.13%), Postives = 259/563 (46.00%), Query Frame = 2
Query: 452 VVIVIEDENDNAPDXXXXXXXXXXXXNDATQLDHNLPKALDKDCPIYGIKNYSL-SGNKVEYFSLKIRQ------FQPFLSVKKSFDFENPSEKQFNLSLNAIDNGGKS--ATLQLIVNVIDINDNPPIFQKKIVNVTIQENTTFPDAILKLNATDLDSGNNAQISYKFSSINRPIIRETFQLQSETGKIYLLKTLDYELYSEQNFDINVLAIDHGSP-QLSDSCIIKVNVTDINDNSPVIEIVH----SQPIPENEQITDPALKLYVSDYDSIDN---DVKCQAEKIGRRLKLEQVEKSSYFIYATEIYDYEKEKNLSLSILCQDSGKEPRYTKQLLTIFIKDVNDNRPKFLRSFYRKSINEDQEKLKPFTKVQALDKDSDDFGKVKYSIG--LKDRKY---FSIDEISGEVRLANEIDRETKDFYNVSVIATDGGG--LKDYSYIEISILDVNDNYPKLKSGS-SMRVNENLPVGSVVGYISVIDLDLGDNSKVEWTYDFLGNSSSMLQIENCTVYTSTVLDRESIEHLHILITMVDMGYPRLTSSATITVSVIDENDNIP 2065
V++ ++D NDN+P F + + + L A+D D ++Y++ SGN F L ++ + + S + + L+++A D G + L+L + V D NDN P F + TI EN +IL+++A+D D G NA+I Y + + P + F + TG I LDYE +++++ I V A D GS QLS S I+++ V D+NDN+PVI + + S + EN I ++ VSD DS N +V + +K + + S I + D E + L +C D G PR T++ I + DVND PKF R Y + E+ V A+D+D ++ Y+I + R Y F+ID SG + A ++DRE ++V+ D G L D + +++ D NDN P S + + EN P GS V + D D+G+NS + ++ N+ L V S LD E + D G + +AT+ VS+ D NDN P
Sbjct: 44 VLVYVQDLNDNSPSFVRGTSAKLVVFENDKDFRQKL-IAVDSDFGSNSTQSYTIVSGNVGNVFKLISKRDTDGDLYADLVVNASSIGVDRERLDSYVLNISASDGGNPANHGFLRLSITVEDTNDNKPEFSNVSYSGTIPENIDVGTSILQVSASDKDIGTNAEIQYSIETHSDP--QAIFGIHPTTGVIVNNVRLDYE--AKRSYLIVVKAEDKGSSHQLSSSAIVRIEVLDVNDNNPVIHVSYTLGGSYQVTENATIGTQVARVSVSDADSGKNGEVNVTLEGGDGYFSMKFDVLNDES-IIAVGQSLDRETHDHFFLKAVCIDKGDPPRTTEKSFRINVGDVNDCAPKFDRHTYETRVWENATVNTLVAIVNAVDQDFGSNSELVYTIANTTESRSYLHWFAIDPSSGMITTATDLDREQIPQVVLTVLVHDRGSPPLSDNCSVIVNLTDSNDNDPYFNQSSYNASLFENSPSGSPVVQLLAQDPDIGENSLILYSI-LTPNTPFFLDPRKGLVTNSRTLDHEVQSSYTFQVAATDGG--GRSCNATVHVSLTDLNDNQP 597 HSP 5 Score: 146.362 bits (368), Expect = 2.447e-35 Identity = 177/629 (28.14%), Postives = 286/629 (45.47%), Query Frame = 2
Query: 452 VVIVIEDENDNAPDXXXXXXXXXXXXNDATQLDHNLPKALDKDCPIYGIKNYSLSGNKVEYFSLKIRQF---QPFLSVKKSFDFENPSEKQFNLSLNAIDNGGKSATL---QLIVNVIDINDNPPIFQKKIVNVTIQENTTFPDAILKLNATDLDS-GNNAQISYKFSSINRPIIRETFQLQSETGKIYLLKTLDYELYSEQNFDINVLAIDHGSPQ-LSDSCIIKVNVTDINDNSPV-IEIVHSQPIPENEQITDPALKLYVSDYDSIDNDVKCQAEKI-GRRLKLEQVEKSSYFIYATEIYDYEKEKNLSLSILCQDSGKEPRYTK-QLLTIFIKDVNDNRPKFLRSFYRKSINEDQEKLKPFTKVQALDKDSDDFGKVKYSIGLKD-RKYFSIDEISGEVRLANEIDRETKDFYNVSVIATDGG-----GLKDYSYIEISILDVNDNYPKLKSGSSMRVNENLPVGSVVGYISVIDLDLGDNSKVEWTYDFLGNSSSMLQIENCTVYTSTVLDRESIEHLHILITMVDMGYPRLTSSATITVSVIDENDNIPKVIYPKTGSLVEEREMDHIAVNSPKYTTVLSIKSFDPDLGINGDVLYHILPSNGSQYFIINQTSGVLKTTWIYD 2287
V ++++D NDN P F ++S+ + EN+ A D D G Y F ++ QF + + S + ++ + S+ A D GG S + Q+ V V D+ND P F K +VT+ E+ ++L L ATD D G N+ I+Y + P + F L TG + L+ LD E+ ++V+A D G Q L I++NV D+NDN PV I + +PE I + D D DN K + + + G ++ +++ I D+E L + D GK+ + T QL+TI+++D NDNRP F ++ I E+ T ++A D DS ++ Y+I + R +F I+ +G ++ + IDRE Y++ V ATD L + + ++I I D+NDN PK S + V E+ P V I+ +D D G VE+ L ++ + LD E + + I+ D+G P LTS V V+D NDN P+ + + ++ N P T+V+ + ++D D G N ++ Y I F I++ SG++ T I D
Sbjct: 1002 VKVIVDDVNDNNPHFQQASYAFFVKENEPVATYLGAVSASDSDEGSNGHVTYR--------FDTQVAQFIVDKQTGKITTSQVLDREAKASYVFSIVATD-GGSSPRVDKTQVTVIVRDVNDCSPKFSKNKYSVTVNEDLPVGSSLLTLIATDDDQQGPNSDITYMI--VAGP---KAFSLNQVTGVLTLVSPLDREV--THRHILHVVASDKGGNQSLETITYIEINVLDVNDNYPVFINETTFKTVPEKLPIGSVVAAVLAVDSDQGDNG-KVRYKIVNGNTDGTFKINETTGVISTLRALDFEVTNRYVLRVSATDMGKKQQKTSYQLVTIYVEDANDNRPTFDKNPIITWIYENVPINTNVTTIKAHDDDSGLNSRIWYTIDSQSPRAHFKINSETGLIQTTHPIDREEISEYSLKVRATDQAFTEQDRLYNTATLKIIIQDLNDNAPKFVSRNLTYVMEDEPFNFQVTSITALDPDTGQGGNVEYRIVSPDTGKFSLDLKTGVLKLIGSLDYEDVPQYTLHISATDLGSPPLTSYQLFNVVVVDVNDNPPE--------FTRDLFIGTVSENKPTGTSVVKVTAYDRDSGSNAELTYSIPSGVEMDKFSIDKHSGLIVTNSILD 1605 HSP 6 Score: 143.665 bits (361), Expect = 1.685e-34 Identity = 156/597 (26.13%), Postives = 269/597 (45.06%), Query Frame = 2
Query: 458 IVIEDENDNAPDXXXXXXXXXXXXNDATQLDHNLPKALDKDCP-----IYGIKNYSLSGNKVEYFSLKIRQFQPFLSVKKSFDFENPSEKQFNLSLNAIDNGGK--SATLQLIVNVIDINDNPPIFQKKIVNVTIQENTTFPDAILKLNATDLDSGNNAQISYKFSSINRPIIRETFQLQSETGKIYLLKTLDYELYSEQNFDINVLAIDHGSPQLSDSCIIKVNVTDINDNSPVIE-IVHSQPIPENEQITDPALKLYVSDYDSIDNDVKCQAEKIGRRLKLEQVEKSSYFIYATEIYDYEKEKNLSLSILCQDSGKEPRYTKQLLTIFIKDVNDNRPKFLRSFYRKSINEDQEKLKPFTKVQALDKDSDDFGKVKYSIGLKDRKYFSIDEISGEVRLANEIDRETKDFYNVSVIATDGGG--LKDYSYIEISILDVNDNYPKLKSGSSM-RVNENLPVGSVVGYISVIDLDLGDNSKVEWTYDFLGNSSSMLQIENCT--VYTSTVLDRESIEHLHIL-ITMVDMGYPRLTSSATITVSVIDENDNIPKVIYPKTGSLVEEREMDHIAVNSPKYTTVLSIKSFDPDLGINGDVLY 2206
I + D ND AP F ++ ++EN + A+D+D +Y I N + S + + +F++ + + D + Q L++ D G S +IVN+ D NDN P F + N ++ EN+ +++L A D D G N+ I Y + N P F L G + +TLD+E+ S F V A D G S + + V++TD+NDN PV + +S EN +I +L D DS + + G ++ V+ S A ++ D E + N L++ D G + K ++ I + DVND P F ++ Y +I E + L V A+ +D +V YSI + + +G + L +E+D E ++V A D G L Y+ + I+++D+NDN P+ S S + R+ E+ P+G +SV D D G +V ++ L N ++ +++ T + + ++D + + L + D G P +S+A + + V+D ND P H+ +P + ++ + + D D G NG + Y
Sbjct: 377 INVGDVNDCAPKFDRHTYETRVWENATVNTLVAIVNAVDQDFGSNSELVYTIANTTESRSYLHWFAIDPSSGM----ITTATDLDREQIPQVVLTVLVHDRGSPPLSDNCSVIVNLTDSNDNDPYFNQSSYNASLFENSPSGSPVVQLLAQDPDIGENSLILYSILTPNTP-----FFLDPRKGLVTNSRTLDHEVQSSYTF--QVAATDGGG--RSCNATVHVSLTDLNDNQPVFDPSSYSVEYFENTRIGQSICQLKAIDRDSPKFAITRFIIEQGNADEVFSVDGSGLITLA-KLLDRETQDNYLLTVKAVDGGGQDSVNKAIVNITVLDVNDEPPIFSKAEYNFTIQEHSQALSVIGHVHAISRDKGTNAEVVYSISKGNTDNIVLINSTGTLYLQSEVDHEKIPSLYLTVQAKDKGTPPLFGYANVTIAVIDINDNSPQFNSSSILVRLPEDTPIGHTFYTVSVFDADSGVLGRV--SFSLLSNPGTLFNLDSNTGALSLTKLIDYGNSARSYTLPVQAQDGGSPPRSSTAMLELKVVDVNDYSP--------VFGNWSYTAHVLETTPPDSNIIEVVATDVDSGENGRISY 949 HSP 7 Score: 133.265 bits (334), Expect = 2.502e-31 Identity = 146/620 (23.55%), Postives = 268/620 (43.23%), Query Frame = 2
Query: 446 VKVVIVIEDENDNAPDXXXXXXXXXXXXNDATQLDHNLPKALDKDCPIYGIKNYSLSGNKVEYFSLKIRQFQPFLSVKKSFDFENPSEKQFNLSLNAIDNGGK---SATLQLIVNVIDINDNPPIFQKKIV---NVTIQENTTFPDAILKLNATDLDSGNNAQISYKFSSINRPIIRETFQLQSETGKIYLLKTLDYELYSEQNFDINVLAIDHGSPQLSDSCIIKVNVTDINDNSPVIEIVHSQPIPENEQITDPALKLYVSDYDSIDNDVKCQAEKI---------GRRLKLEQVEKSSYFIYATEIYDYEKEKNLSLSILCQDSGKEPRYTKQLLTIFIKDVNDNRPKFLRSFYRKSINEDQEKLKPFTKVQALDKDSDDFGKVKYSIGLKDRKYFSIDEISGEVRLANEIDRETKDFYNVSVIATDGGGLKDYSYIEISILDVNDNYPKLKSGS-SMRVNENLPVGSVVGYISVIDLDLGDNSKVEWTYDFLGNSSSMLQIENCTVYT-STVLDRESIEHLHILITMVDMGYPRLTSSATITVSVIDENDNIPKVIYPKTGSLVEEREMDHIAVNSPKYTTVLSIKSFDPDLGINGDVLYHILPSNGSQYFIINQT 2254
+++ I +ED NDN P+FS S++ +I EN A DKD YS+ + I + D+E +++ + + + A D G S++ + + V+D+NDN P+ + + EN T + +++ +D DSG N +++ F + ++ I + ++LD E + +F + + ID G P + ++NV D+ND +P + H+ E + + V+ +++D D +E + L ++ SS I D E+ + L++L D G P + + + D NDN P F +S Y S+ E+ P ++ A D D + + YSI + +F +D G V + +D E + Y V ATDGGG + + +S+ D+NDN P S S+ EN +G + + ID D + + + GN+ + ++ + T + +LDRE+ ++ + + VD G + A + ++V+D ND P + ++E +S + + + + D G N +V+Y I N +IN T
Sbjct: 156 LRLSITVEDTNDNKPEFSNVSYSGTIPENIDVGTSILQVSASDKDIGTNAEIQYSIETHSDPQAIFGIHPTTGVIVNNVRLDYE--AKRSYLIVVKAEDKGSSHQLSSSAIVRIEVLDVNDNNPVIHVSYTLGGSYQVTENATIGTQVARVSVSDADSGKNGEVNVTLEG-GDGYFSMKFDVLNDESIIAVGQSLDRETH--DHFFLKAVCIDKGDPPRTTEKSFRINVGDVNDCAPKFD-RHTY---ETRVWENATVNTLVAIVNAVDQDFGSNSELVYTIANTTESRSYLHWFAIDPSSGMITTATDLDREQIPQVVLTVLVHDRGSPPLSDNCSVIVNLTDSNDNDPYFNQSSYNASLFENSPSGSPVVQLLAQDPDIGENSLILYSILTPNTPFF-LDPRKGLVTNSRTLDHEVQSSYTFQVAATDGGGRSCNATVHVSLTDLNDNQPVFDPSSYSVEYFENTRIGQSICQLKAIDRDSPKFAITRFIIE-QGNADEVFSVDGSGLITLAKLLDRETQDNYLLTVKAVDGGGQDSVNKAIVNITVLDVNDEPPIFSKAEYNFTIQE--------HSQALSVIGHVHAISRDKGTNAEVVYSISKGNTDNIVLINST 756 HSP 8 Score: 125.946 bits (315), Expect = 4.850e-29 Identity = 178/680 (26.18%), Postives = 290/680 (42.65%), Query Frame = 2
Query: 284 YFRI-SDSGEIRITKVFDRDDVNNVCGPLGCCDKPSCEIVLDIIVTVIPKNERI--PVKVVIVIEDENDNAPDXXXXXXXXXXXXNDATQLDHNLPKALDKDCPIYGIKNYSLSGNKVEYFSLKIRQFQPFLSVKKSFDFENPSEKQFNLSLNAIDNGGKSAT-LQLIVNVIDINDN-PPIFQKKIVNVTIQENTTFPDAILKLNATDLDSGNNAQISYKFSSINRPIIRETFQLQSETGKIYLLKTLDYELYSEQNFDINVLAIDHGSPQLSDSCIIKVNVTDINDNSP-VIEIVHSQPIPENEQITDPALKLY---VSDYDSIDNDVKCQAEKIGRRLKLEQVEKSSYFIYATEIYDYEKEKNLSLSILCQDSGKEPRYTK-QLLTIFIKDVNDNRPKFLRSFYRKSINEDQEKLKPFTKVQALDKDSDDFGKVKYSIGLKDRKYFSIDEISGEVRLANEIDRETKDFYNVSVIATDGGGLKDYSY--IEISILDVNDNYPKL-KSGSSMRVNENLPVGSVVGYISVIDLDL--GDNSKVEWTYDFLGNSSSMLQIENCT--VYTSTVLDRESIEHLHILITMVDMGYPRLTSSATITVSVIDENDNIPKVI--YPKTGSLVEEREMDHIAVNSPKYTTVLSIKSFDPDLGINGDVLYHILPSNGSQYFIINQTSGVL 2266
+F+I S++G I+ T DR++++ + D+ E +R+ + I+I+D NDNAP S + E++ ALD D G Y + FSL ++ L + S D+E+ Q+ L ++A D G T QL V+ ++ PP F + + T+ EN +++K+ A D DSG+NA+++Y SI + + F + +G I LD E + + + V A P S +++NV D NDN P I V + +PEN PA +Y V D D +N + G + +S+ + T D E + + LS+ +D P YT +TIFI+D NDN P F +S Y +I+E + A DKDS G + Y++ +SID +G V A + K YN IA D G + + I I D N++ P+ K+ + + N ++V ++ D D N KV + D NS+S+ +E+ T V TS + I D G P L + + + + D+ P+ + P S+ E ++ TTV + S D V Y I+ N + F ++ +GV+
Sbjct: 1377 HFKINSETGLIQTTHPIDREEISEYSLKVRATDQAFTE------------QDRLYNTATLKIIIQDLNDNAP-KFVSRNLTYVMEDEPFNFQVTSITALDPDTGQGGNVEYRIVSPDTGKFSLDLKT--GVLKLIGSLDYED--VPQYTLHISATDLGSPPLTSYQLFNVVVVDVNDNPPEFTRDLFIGTVSENKPTGTSVVKVTAYDRDSGSNAELTY---SIPSGVEMDKFSIDKHSGLIVTNSILDRE--KKDTYFLTVHATGVSYPFRVSSTSVRINVMDRNDNPPKFISPVVTLKVPENS----PARLIYTLTVQDLDYGNNTKVLYSIMSGNTDGAFTIGRSTGELSTTTKLDRETKASYQLSVQAKDI-TPPYYTAFANITIFIEDQNDNPPVFQQSLYSSTISELTPPGTSILNLTASDKDSGSNGNIVYTLSNDTYGVYSIDSRTGIVYSAARFETSIKQEYNFFCIAKDQGQDPKMAIVPVRIKIEDKNNHAPQFTKTPYEVHIFPNTSASALVTMVTATDADTDKSTNGKVTYRLDDSKNSTSLFVVESNTGSVRTSAGFSNPPQGRHALYIIAEDHGSPPLRGYGIVQIVIGNIQDDPPRFLNQTPARVSIPENSKV------GSYITTVRARASSD------AQVTYSIISGNKGRAFYVDPFTGVI 2017 HSP 9 Score: 125.946 bits (315), Expect = 5.461e-29 Identity = 144/544 (26.47%), Postives = 242/544 (44.49%), Query Frame = 2
Query: 668 LSVKKSFDFENPSEKQFNLSLNAIDNGGKSATLQLIVNVIDINDNPPIFQKKI-VNVTIQENTTFPDAILKLNATDLDSGNNAQISYKFSSINRPIIRETFQLQSETGKIYL-----LKTLDYELYSEQNFDINVLAIDHGSPQLSDSCIIKVNVTDINDNSPVIE-IVHSQPIPENEQITDPALKLYVSDYD-SIDNDVKCQAEKIGRRLKLEQVEKSSYFIYATEIYDYEKEKNLSLSILCQDSGKEPRYTKQ-LLTIFIKDVNDNRPKFLRSFYRKS---INEDQEKLKPFTKVQALDKDSDDFGKVKYSIGLKDRKYFSI--DEISGE--VRLANEIDRETKDFYNVSVIATDGGGLKDYS--YIEISILDVNDNYPKLKSGS-SMRVNENLPVGSVVGYISVIDLDLGDNSKVEWTYDFLGNSSSMLQI-----ENCTVYTSTVLDRESIEHLHILITMVDMGYPRLTSSATITVSVIDENDNIPKVIYPK-TGSLVEEREMDHIAVNSPKYTTVLSIKSFDPDLGINGDVLYHILPSN 2224
++ K D E S +NL++ KS T+ +V V D+NDN P F + + + EN D KL A D D G+N+ SY S N + + + G +Y ++ + ++ +N+ A D G+P + + V D NDN P + +S IPEN + L++ SD D + +++ E + + ++ I DYE +++ + + +D G + + ++ I + DVNDN P S+ + E+ +V D DS G+V ++ D YFS+ D ++ E + + +DRET D + + + D G + I++ DVND PK + RV EN V ++V ++ +D D G NS++ +T S S L + + T+T LDRE I + + + + D G P L+ + ++ V++ D NDN P SL E NSP + V+ + + DPD+G N +LY IL N
Sbjct: 14 ITTKTVLDREKVS--AYNLTIVEFSTPPKSYTV--LVYVQDLNDNSPSFVRGTSAKLVVFENDK--DFRQKLIAVDSDFGSNSTQSYTIVSGNVGNVFKLISKRDTDGDLYADLVVNASSIGVDRERLDSYVLNISASDGGNPANHGFLRLSITVEDTNDNKPEFSNVSYSGTIPENIDVGTSILQVSASDKDIGTNAEIQYSIETHSDPQAIFGIHPTTGVIVNNVRLDYEAKRSYLIVVKAEDKGSSHQLSSSAIVRIEVLDVNDNNPVIHVSYTLGGSYQVTENATIGTQVARVSVSDADSGKNGEVNVTLEGGD-GYFSMKFDVLNDESIIAVGQSLDRETHDHFFLKAVCIDKGDPPRTTEKSFRINVGDVNDCAPKFDRHTYETRVWENATVNTLVAIVNAVDQDFGSNSELVYTIANTTESRSYLHWFAIDPSSGMITTATDLDREQIPQVVLTVLVHDRGSPPLSDNCSVIVNLTDSNDNDPYFNQSSYNASLFE---------NSPSGSPVVQLLAQDPDIGENSLILYSILTPN 541 HSP 10 Score: 114.005 bits (284), Expect = 2.439e-25 Identity = 126/460 (27.39%), Postives = 197/460 (42.83%), Query Frame = 2
Query: 971 LQSETGKIYLLKTLDYELYSEQNFDINVLAIDHGSPQLSDSCIIKVNVTDINDNSPVIEIVHSQPIPENEQITDPALKLYVSDYDSIDNDVKCQ---AEKIGRRLKLEQVEKSSYFIYATEI-------YDYEKEKNLSLSILCQDSGKEPRYTKQLLTIFIKDVNDNRPKFLRSFYRKSINEDQEKLKPFTKVQALDKDSDDFGKVKYSIGLKD--RKYFSIDEISGEVRLANEIDRETKDFYNVSVIATDGGG---LKDYSYIEISILDVNDNYPKLKS----GSSMRVNENLPVGSVVGYISVIDLDLGDNSKVEWTYDFLGNSSSM---LQIENCTVYTSTVLDRESIEHLHILITMVDMGYPRLTSSATITVSVIDENDNIPKVIYPKTGSLVEEREMDHIAVNSPKYTTVLSIKSFDPDLGINGDVLYHILPSNGSQ----YFIINQTSGVLKT 2272
L+ G I LD E S N I ++ +P S + ++ V D+NDNSP S + E D KL D D N + + +G KL + +YA + D E+ + L+I D G + L+I ++D NDN+P+F Y +I E+ + +V A DKD +++YSI + F I +G + +D E K Y + V A D G L + + I +LDVNDN P + G S +V EN +G+ V +SV D D G N +V T + SM + + + LDRE+ +H + +D G P T+ + ++V D ND PK E R ++ VN T V + + D D G N +++Y I + S+ +F I+ +SG++ T
Sbjct: 7 LEYNAGVITTKTVLDREKVSAYNLTI----VEFSTPPKSYTVLVYVQ--DLNDNSPSFVRGTSAKLVVFENDKDFRQKLIAVDSDFGSNSTQSYTIVSGNVGNVFKLISKRDTDGDLYADLVVNASSIGVDRERLDSYVLNISASDGGNPANHGFLRLSITVEDTNDNKPEFSNVSYSGTIPENIDVGTSILQVSASDKDIGTNAEIQYSIETHSDPQAIFGIHPTTGVIVNNVRLDYEAKRSYLIVVKAEDKGSSHQLSSSAIVRIEVLDVNDNNPVIHVSYTLGGSYQVTENATIGTQVARVSVSDADSGKNGEVNVTLEGGDGYFSMKFDVLNDESIIAVGQSLDRETHDHFFLKAVCIDKGDPPRTTEKSFRINVGDVNDCAPKF----DRHTYETRVWENATVN----TLVAIVNAVDQDFGSNSELVYTIANTTESRSYLHWFAIDPSSGMITT 452 HSP 11 Score: 95.9005 bits (237), Expect = 7.462e-20 Identity = 83/319 (26.02%), Postives = 149/319 (46.71%), Query Frame = 2
Query: 641 LKIRQFQPFLSVKKSFDFENPSEKQFNLSLNAIDNGGKSATLQLIV--NVIDINDNPPIFQKKIVNVTIQENTTFPDAILKLNATDLDSGNNAQISYKFSSINRPIIRETFQLQSETGKIYLLKTLDYELYSEQNFDINVLAIDHGSPQLSDSCIIKVNVTDINDNSPVIEIVHSQPIPENEQITDP-ALKLYVSDYDSIDNDVKCQAE-------KIGRRLKLEQVEKSSYFIYATEIYDYEKEK--NLSLSILCQDSGKEPRYTKQLLTIFIKDVNDNRPKFLRSFYRKSINEDQEKLKPFTKVQALDKDSDDFGKV 1561
+I Q +SV K D+E ++++F L ++AID+ S +++ V NV D+ND P+F + E ++ ++A D DSG N ++ + S + + +F + +TG I + LD+E + ++V A D GSP + + + V D+NDN PV + P P + Q+ + L + + ++ D D A G+ L L ++K S ++ +DYE SL+I D+G P + + + + D ++ P F R Y+ + + + +V A D+DS D G+V
Sbjct: 2350 FRIGQRSGVISVNKPLDYE--TKRRFLLVVSAIDDTAPSKPVRVPVYINVSDVNDEKPVFGQSGYMAQWSEGIPVGTIVVNVSAADKDSGANGRVWFAIQSGDD---KGSFAIDRKTGVIRTQRALDHETIKTHH--VSVRATDEGSPPMHTDVSVTIRVLDLNDNPPVFRV----PGPNDVQVLENLPLNSRLYEINATDRDSGANARLSFTVIGGTGQGLFL--IDKFSGWLTTNITFDYENTAVYQYSLTIKATDAGNPPLSSNITIIVNVADEDEYDPSFNRMDYKFDVPGNAKIGDFVGQVTATDRDSGDQGRV 2655 HSP 12 Score: 70.8626 bits (172), Expect = 3.495e-12 Identity = 88/330 (26.67%), Postives = 147/330 (44.55%), Query Frame = 2
Query: 287 FRISDSGEIRITKVFDRDDVNNVCGPLGCCDKPSCEIVLDIIVTVIP-KNERIPVKVVIVIEDENDNAPDXXXXXXXXXXXXNDATQLDHNLP--------KALDKDCPIYGIKNYSL-SGNKVEYFSLKIRQFQPFLSVKKSFDFENPSEKQFNLSLNAIDNGGK--SATLQLIVNVIDINDNPPIFQKKIVN-VTIQENTTFPDAILKLNATDLDSGNNAQISYKFSSINRPIIRETFQLQSETGKIYLLKTLDYELYSEQNFDINVLAIDHGSPQLSDSCIIKVNVTDINDNSPVI-EIVHSQPIPENEQITDPALKLYVSDYDSID 1234
+ I +S RI + R V +V PL K +V+ I P K R+PV I + D ND P + Q +P A DKD G +++ SG+ + S I + + +++ D E + K ++S+ A D G + + + V+D+NDNPP+F+ N V + EN + ++NATD DSG NA++S+ ++ + F + +G + T DYE + + + + A D G+P LS + I VNV D ++ P + + +P N +I D ++ +D DS D
Sbjct: 2342 YNIENSNYFRIGQ---RSGVISVNKPLDYETKRRFLLVVSAIDDTAPSKPVRVPV--YINVSDVNDEKP--------VFGQSGYMAQWSEGIPVGTIVVNVSAADKDSGANGRVWFAIQSGD--DKGSFAIDRKTGVIRTQRALDHE--TIKTHHVSVRATDEGSPPMHTDVSVTIRVLDLNDNPPVFRVPGPNDVQVLENLPLNSRLYEINATDRDSGANARLSF---TVIGGTGQGLFLIDKFSGWLTTNITFDYENTAVYQYSLTIKATDAGNPPLSSNITIIVNVADEDEYDPSFNRMDYKFDVPGNAKIGDFVGQVTATDRDSGD 2651 HSP 13 Score: 55.0694 bits (131), Expect = 2.060e-7 Identity = 48/172 (27.91%), Postives = 80/172 (46.51%), Query Frame = 2
Query: 446 VKVVIVIEDENDNAPDXXXXXXXXXXXXNDATQLDHNLP--------KALDKDCPIYGIKNYSLSGNKVEYFSLKIRQFQPFLSVKKSFDFENPSEKQFNLSLNAIDNGGK--SATLQLIVNVIDINDNPPIFQKKIVNVTIQENTTFPDAILKLNATDLDSGNNAQISYKF 931
V V I + D NDN P ND Q+ NLP A D+D ++++ G + L I +F +L+ +FD+EN + Q++L++ A D G S+ + +IVNV D ++ P F + + N D + ++ ATD DSG+ ++ + F
Sbjct: 2496 VSVTIRVLDLNDNPP------VFRVPGPNDV-QVLENLPLNSRLYEINATDRDSGANARLSFTVIGGTGQGLFL-IDKFSGWLTTNITFDYENTAVYQYSLTIKATDAGNPPLSSNITIIVNVADEDEYDPSFNRMDYKFDVPGNAKIGDFVGQVTATDRDSGDQGRVFFVF 2659
BLAST of Protocadherin alpha-2 vs. Ensembl Nematostella
Match: EDO46189 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RQM0]) HSP 1 Score: 211.846 bits (538), Expect = 1.122e-55 Identity = 192/679 (28.28%), Postives = 309/679 (45.51%), Query Frame = 2
Query: 260 SSFTKFNQYFRISDSGEIRITKVFDRDDVNNVCGPLGCCDKPSCEIVLDIIVTVIPKNERIPVKVVIVIEDENDNAPDXXXXXXXXXXXXNDATQLDHNLPKALDKDCPIYGIKNYSLSGNKVEYFSLKIRQFQPFLSVKKSFDFENPSEKQFNLSLNAIDNGGKSATLQLIVNV--IDINDNPPIFQKKIVNVTIQENTTFPDAILKLNATDLDSGNNAQISYKFSSINRPIIRETFQLQSETGKIYLLKTLDYELYSEQNFDINVLAIDHGSPQLSDSCIIKVNVTDINDNSPVIE-IVHSQPIPENEQITDPALKLYVSDYDSIDNDVKCQAEKIGRRLKLEQVEKSSYFIYATEIYDYEKEKNLSLSILCQDSGKEPRYTKQLLTIFIKDVNDNRPKFLRSFYRKSINEDQEKLKPFTKVQALDKDSDDFGKVKYS-IGLKDRKYFSIDEISGEVRLANEIDRETKDFYNVSVIATD--GGGLKDYSYIEISILDVNDNYPKLKSGSSMRVNENLPVGSVVGYISVIDLDLGDNSKVEWTYDFLGNSSSMLQIENCT--VYTSTVLDRESIEHLHILITMVDMGYPRLTSSATITVSVIDENDNIPKVIYPKTGSLVEEREMDHIAVNSPKYTTVLSIKSFDPDLGINGDVLYHILPSNGSQYFIINQTSGVLKT 2272
S F+ N++ S +GEIR D + ++ + D T +P +I ++D NDNAP F+ S + ++E+ A A+D D I +YSL YF++ Q + K +FD E ++ + ++L A D G S + Q V + +D+NDN P+F ++ E+ A++ + A+D D+GNNA + Y F+S N F L + TG + + ++LD+E S ++V D GSP L+D+ + +NV DINDN PV + + EN T ++ +D DS N G + ++ S+ I + DYE + L++ +D G +Y +TIFI+DVND+ P F S Y K I E V A D DS G+++Y I + F+ID SG +R+++E+DRET Y++ V A D + + I++ D+NDN P + RV+E+ G +G ++ D D N V + L +++ + I T + T LD E + +T D G P +S + V V D NDN P+ V E +A V + + D D G NG + Y IL N + F +++ +G + T
Sbjct: 107 SLFSGENKFMMNSKTGEIRTVTPLDHETKDSYTMRISAFDGKHT--------TFVP---------LITVDDVNDNAPFFALSVYKTGVYEDVAVGSIVRQLTAVDLDVGINARLSYSLVSGDTSYFTV---DSQGVIRTKGAFDRE--TKASYQVALRAQDGGSPSRSGQATVEIEILDVNDNRPVFSSAQYTASVDEDVAIGAAMVTVTASDKDNGNNADLRYSFTSGN---TNHAFTLDAVTGVVTVSRSLDFEQRSSYALGLSV--TDRGSPPLTDTSHLLINVNDINDNPPVFSPSAYQSRVKEN---TPAGTQVSATDRDSSTNGALVFGIIKGNDDGVFTIDGSTGIISIAKSPDYENKTRYDLTVQARDRGVPVKYDTAQVTIFIEDVNDHSPVFSPSNYSKQIPESTVIGSTVVTVTATDLDSGPRGRLEYRLISGNVKGAFNIDANSGSIRVSSELDRETTPSYSLQVEARDGGSTSRSSSTRVTIALQDINDNSPIFQGPYVFRVSESSSPGHQIGQVAATDADDSSNGDVRYA---LSDNTDVFSINTSTGLITLKTQLDYEKKTQYMVTVTAKDGGTPSRSSLTVVKVMVDDVNDNPPQFAKSLYTCTVGENLAAGVA--------VCYVTATDADSGANGKISYSILSGNENMAFAMDRFTGEITT 744 HSP 2 Score: 202.986 bits (515), Expect = 7.114e-53 Identity = 183/615 (29.76%), Postives = 288/615 (46.83%), Query Frame = 2
Query: 452 VVIVIEDENDNAPDXXXXXXXXXXXXNDATQLDHNLPKALDKDCPIYGIKNYSL-SGNKVEYFSLKIRQFQPFLSVKKSFDFEN-PSEKQFNLSLNAIDNGG--KSATLQLIVNVIDINDNPPIFQKKIVNVTIQENTTFPDAILKLNATDLDSGNNAQISYKFSSINRPIIRETFQLQSETGKIYLLKTLDYELYSEQNFDINVLAIDHGSPQLSDSCIIKVNVTDINDNSP-VIEIVHSQPIPENEQITDPALKLYVSDYDSIDNDVKCQAEKIGRRLKLEQVEKSSYFIYATEIYDYEKEKNLSLSILCQDSGKEPRYTKQLLTIFIKDVNDNRPKFLRSFYRKSINEDQEKLKPFTKVQALDKDSDDFGKVKYSIGLKDRKYFSIDEISGEVRLANEIDRETKDFYNVSVIATDGG--GLKDYSYIEISILDVNDNYPKL-KSGSSMRVNENLPVGSVVGYISVIDLDLGDNSKVEWTYDFLGNSSSMLQIENCT--VYTSTVLDRESIEHLHILITMVDMGYPRLTSSATITVSVIDENDNIPKVIYPKTGSLVEEREMDHIAVNSPKYTTVLSIKSFDPDLGINGDVLYHILPSNGSQYFIINQTSGVL 2266
V I I DENDN P +I E+ T A D+D G Y++ SGN+ F L R LSV+ + D E PS + L + A D G +S T + V+V+D+NDN P F+K + + I+E+ + +L++ D D G+N I+ S + F + S TG + LDYE + + + V A D GSP S + +K+ + ++NDN P + IPE+ I +KL +D D G K++Q SS I + D E N +L + ++G + TI + DVNDN P F Y KS++E+ + KV A D+D + KV Y + + D F ++ +G V +DRE + Y++ V A D G + I ++I D+NDN P+ +S ++ V EN GS + + D D G N +V ++ GN + +I++ T + V+DRE++ ++ I+ D G P S+A + ++V DENDN P +T ++E +++ S V + + D D G N V Y I+ + S F IN +GVL
Sbjct: 776 VNISIADENDNQP-TFTGPSRFNISEDSPTGTRVGQLTATDRDIGPNGAVTYAIISGNQGNSFQLDPRS--GILSVRSTLDRETIPS---YTLVVKASDAGSPQQSITASIHVSVLDVNDNAPRFEKSLFSGEIREDASVHSTVLQVKVEDKDEGSNGAITLSLSGEGS----DNFTIDS-TGFVLSKTPLDYETTAA--YQLTVTARDGGSPSKSATAQVKITIINVNDNVPSFVSPAQVTSIPEDVAINTHVVKLNATDSDGTPLTFDIVEGNAGSSFKIDQ---SSGLISVAKRLDRETTANYTLVVRATETGSQGESVYNNATIRVLDVNDNAPVFNPGSYAKSLHENLPIGQTVAKVTATDRDEGENAKVTYELSVGDTSKFEVNPATGLVTTKRPLDREDQASYSLRVTAMDHGKPSQSAVAAITLTINDLNDNSPQFSQSKYTLTVTENTANGSNILRVLASDPDAGANGRVTYSI-ISGNHGNAFRIDSTTGRITVVGVVDREALASYNLTISAKDSGVPPWVSTAFVAITVADENDNSPIFASNETSYGIDE----GVSIGS----RVAVVTATDRDEGSNAQVFYSIVRGDTSA-FAINAMNGVL 1364 HSP 3 Score: 193.356 bits (490), Expect = 7.975e-50 Identity = 190/624 (30.45%), Postives = 292/624 (46.79%), Query Frame = 2
Query: 446 VKVVIVIEDENDNAPDXXXXXXXXXXXXNDATQLDHNLPKALDKDCPIYGIKNYSL-SGNKVEYFSLKIRQFQPFLSVKKSFDFENPSEKQFNLSLNAIDNGGKS--ATLQLIVNVIDINDNPPIFQKKIVNVTIQENTTFPDAILKLNATDLDSGNNAQISYKFSSINRPIIR---ETFQLQSETGKIYLLKTLDYELYSEQNFDINVLAIDHGSPQLSDSCIIKVNVTDINDNSPVIEIVHSQP----IPENEQITDPALKLYVSDYDSIDNDVKCQAEKIGRRLKLEQVEKSSYFIYATEIYDYEKEKNLSLSILCQDSGKEPRYT-KQLLTIFIKDVNDNRPKFLRSFYRKSINEDQEKLKPFTKVQALDKDSDDFGKVKYSI-GLKDRKYFSIDEISGEVRLANEIDRETKDFYNVSVIATDGGG--LKDYSYIEISILDVNDNYPKL-KSGSSMRVNENLPVGSVVGYISVIDLDLGDNSKVEWTYDFLGNSSSMLQIENCTVYTSTVLDRESIEHLHILITMVDMGYPRLTSSATITVSVIDENDNIPKVIYPKTGSLVEEREMDHIAVNSPKYTTVLSIKSFDPDLGINGDVLYHILPSNGSQYFIINQTSGVLKT 2272
+ + I D NDN+P FS+S +T+++ EN A + A D D G YS+ SGN F +I ++V D E + +NL+++A D+G +T + + V D NDN PIF + I E + + + ATD D G+NAQ+ Y I+R F + + G + + K ++ E + + + A D GSP ++ + V V D+NDN PV +SQ + EN + L + D D N V + G K ++ +S I T D+E++ L + DS +YT K +TI + ++ND P F + Y S+ E+ KV A D+DS FG + YSI G KD FSID+ SG + A+ +DRE Y + V TD G L + +++ I ILD NDN PK S S + EN S ++ D D G N+++ TY+ N + M+ + + + LDRE+ + I D G P SS TI V+VID ND+ P + V E N PK T V+ I + D D G+N ++ + +L + F ++ T+G + T
Sbjct: 1187 AAITLTINDLNDNSPQFSQSKYTLTVTENTANGSNILRVLASDPDAGANGRVTYSIISGNHGNAF--RIDSTTGRITVVGVVDRE--ALASYNLTISAKDSGVPPWVSTAFVAITVADENDNSPIFASNETSYGIDEGVSIGSRVAVVTATDRDEGSNAQVFYS-------IVRGDTSAFAINAMNGVLTVKKEINRETV--PTYTLTIRASDRGSPMMTSDKELTVVVNDVNDNPPVF---NSQSYIGSVRENSAQSTSVLTVAADDSDVGANAVLRYSIISGNDEKRFKINSTSGVIMTTTPLDFEEKSQYGLEVTATDS----KYTAKTNVTIRVINLNDITPAFTQQNYTASVRENSPTSTSVVKVSASDRDS--FGSLSYSIVGGKDSDKFSIDQRSGIISTADVLDRELVSLYAIQVRVTDAGNPPLSNLTWVTIKILDENDNSPKFDSSSYSSSILENSAPSSFSFKLAATDADEGTNARI--TYNLSRNDAFMIGASSGVITLAQPLDRENKSTYDLAIQARDHGTPPQASSITIRVTVIDINDHRPLINSSSLRGSVRE--------NQPKETHVMRILASDADTGLNAELTFSLLSNEHKSVFTLDNTTGDIST 1778 HSP 4 Score: 179.489 bits (454), Expect = 1.575e-45 Identity = 157/560 (28.04%), Postives = 260/560 (46.43%), Query Frame = 2
Query: 638 SLKIRQFQPFLSVKKSFDFENPSEKQFNLSLNAIDNG--GKSATLQLIVNVIDINDNPPIFQKKIVNVTIQENTTFPDAILKLNATDLDSGNNAQISYKFSSINRPIIRET--FQLQSETGKIYLLKTLDYELYSEQNFDINVLAIDHGSPQLSDSCIIKVNVTDINDNSPVI-EIVHSQPIPENEQITDPALKLYVSDYDSIDNDVKCQAEKIGRRLKLEQVEKSSYFIYATEIYDYEKEKNLSLSILCQDSGKEPRYTKQLLTIFIKDVNDNRPKFLRSFYRKSINEDQEKLKPFTKVQALDKDSDDFGKVKYSIGLKDRKYFSIDEISGEVRLANEIDRETKDFYNVSVIATDGGGLKDYSYIEISIL--DVNDNYPKLKSGSSM-RVNENLPVGSVVGYISVIDLDLGDNSKVEWTYDFLGNSSSMLQIENCT--VYTSTVLDRESIEHLHILITMVDMGYPRLTSSATITVSVIDENDNIPKVIYPKTGSLVEEREMDHIAVNSPKYTTVLSIKSFDPDLGINGDVLYHILPSNGSQYFIINQTSGVLKTTWIYD 2287
S KI Q +SV K D E + + L + A + G G+S + V+D+NDN P+F ++ EN + K+ ATD D G NA+++Y+ S + +T F++ TG + + LD E + ++ + V A+DHG P S I + + D+NDNSP + ++ + EN L++ SD D+ N + G +++ ++ I + D E + +L+I +DSG P + + I + D NDN P F + I+E V A D+D +V YSI D F+I+ ++G + + EI+RET Y +++ A+D G S E++++ DVNDN P S S + V EN + V ++ D D+G N+ + ++ GN +I + + + T+T LD E + +T D Y T+ +T+ VI+ ND P + V E NSP T+V+ + + D D G + Y I+ S F I+Q SG++ T + D
Sbjct: 1041 SFKIDQSSGLISVAKRLDRE--TTANYTLVVRATETGSQGESVYNNATIRVLDVNDNAPVFNPGSYAKSLHENLPIGQTVAKVTATDRDEGENAKVTYELS------VGDTSKFEVNPATGLVTTKRPLDRE--DQASYSLRVTAMDHGKPSQSAVAAITLTINDLNDNSPQFSQSKYTLTVTENTANGSNILRVLASDPDAGANGRVTYSIISGNHGNAFRIDSTTGRITVVGVVDREALASYNLTISAKDSGVPPWVSTAFVAITVADENDNSPIFASNETSYGIDEGVSIGSRVAVVTATDRDEGSNAQVFYSIVRGDTSAFAINAMNGVLTVKKEINRETVPTYTLTIRASDRGSPMMTSDKELTVVVNDVNDNPPVFNSQSYIGSVRENSAQSTSVLTVAADDSDVGANAVLRYSI-ISGNDEKRFKINSTSGVIMTTTPLDFEEKSQYGLEVTATDSKY---TAKTNVTIRVINLNDITPAFTQQNYTASVRE--------NSPTSTSVVKVSASDRDS--FGSLSYSIVGGKDSDKFSIDQRSGIISTADVLD 1576 HSP 5 Score: 162.155 bits (409), Expect = 2.943e-40 Identity = 166/618 (26.86%), Postives = 276/618 (44.66%), Query Frame = 2
Query: 452 VVIVIEDENDNAPDXXXXXXXXXXXXNDATQLDHNLPK--ALDKDCPIYGIKNYSLSGNKVEYFSLKIRQFQPFLSVKKSFDFENPSEKQFNLSLNAIDNGGKSATLQLIVNVI--DINDNPPIFQKKIVNVTIQENTTFPDAILKLNATDLDSGNNAQISYKFSSINRPIIRETFQLQSETGKIYLLKTLDYELYSEQNFDINVLAIDHGS-PQLSDSCIIKVNVTDINDNSPVIEIVHSQPIPENEQITDPALKLYVSDYDSIDNDVKCQAEKIGRRLKLEQVEKSSYFIYATEIYDYEKEKNLSLSILCQDSGKEPRYTKQLLTIFIKDVNDNRPKFLRSFYRKSINEDQEKLKPFTKVQALDKDSDDFGKVKYSIGLKDRKYFSIDEISGEVRLANEIDRETKDFYNVSVIATDGG--GLKDYSYIEISILDVNDNYPKLKSGSSM-RVNENLPVGSVVGYISVIDLDLGDNSKVEWTYDFL-GNSSSMLQIENCTVYTSTV--LDRESIEHLHILITMVDMGYPRLTSSATITVSVIDENDNIPKVIYPKTGSLVEEREMDHIAVNSPKYTTVLSIKSFDPDLGINGDVLYHILPSNGSQYFIINQTSGVLKT 2272
V I ++D NDN+P ++++ H + + A D D G Y+LS N + FS I +++K D+E + Q+ +++ A D G S + +V V+ D+NDNPP F K + T+ EN A+ + ATD DSG N +ISY S N + F + TG+I LD E + + IN D GS + + + +++ D NDN P I E+ +L +D D N A G + Q++ S + D E + +L + D+G + + + + DVNDN P+F +S + I ED +V+ DKD G + S+ + F+ID +G V +D ET Y ++V A DGG + ++I+I++VNDN P S + + + E++ + + V+ L+ D+ T+D + GN+ S +I+ + S LDRE+ + +++ + G + T+ V+D NDN P V P GS + + N P TV + + D D G N V Y + + S+ F +N +G++ T
Sbjct: 569 VTIALQDINDNSP---IFQGPYVFRVSESSSPGHQIGQVAATDADDSSNGDVRYALSDN-TDVFS--INTSTGLITLKTQLDYEK--KTQYMVTVTAKDGGTPSRSSLTVVKVMVDDVNDNPPQFAKSLYTCTVGENLAAGVAVCYVTATDADSGANGKISYSILSGNENM---AFAMDRFTGEITTRVPLDRETIASYSLTINA---DDGSLVRFMAATTVNISIADENDNQPTFTGPSRFNISEDSPTGTRVGQLTATDRDIGPNGAVTYAIISGNQGNSFQLDPRSGILSVRSTLDRETIPSYTLVVKASDAGSPQQSITASIHVSVLDVNDNAPRFEKSLFSGEIREDASVHSTVLQVKVEDKDEGSNGAITLSLSGEGSDNFTIDS-TGFVLSKTPLDYETTAAYQLTVTARDGGSPSKSATAQVKITIINVNDNVPSFVSPAQVTSIPEDVAINT-----HVVKLNATDSDGTPLTFDIVEGNAGSSFKIDQSSGLISVAKRLDRETTANYTLVVRATETGSQGESVYNNATIRVLDVNDNAP-VFNP--GSYAKS-----LHENLPIGQTVAKVTATDRDEGENAKVTYELSVGDTSK-FEVNPATGLVTT 1157 HSP 6 Score: 162.155 bits (409), Expect = 3.644e-40 Identity = 185/657 (28.16%), Postives = 295/657 (44.90%), Query Frame = 2
Query: 155 FTIPDNNARHSSVGNIISKLPSRFPRG--SYQIITRRSSFTKFNQYFRI-SDSGEIRITKVFDRDDVNNVCGPLGCCDKPSCEIVLDIIVTVIPKNERIP-----VKVVIVIEDENDNAPDXXXXXXXXXXXXNDATQLDHNLPKALDKDCPIYGIKNYSLSGNKVEYFSLKIRQFQPFLSVKKSFDFENPSEKQFNLSLNAIDNGGKSATL--QLIVNVIDINDNPPIFQKKIVNVTIQENTTFPDAILKLNATDLDSGNNAQISYKFSSINRPIIRETFQLQSETGKIYLLKTLDYELYSEQNFDINVLAIDHGSPQLSDSCIIKVNVTDINDNSPVI-EIVHSQPIPENEQITDPALKLYVSDYDSIDN-DVKCQAEKIGRRLKLEQVEKSSYFIYATEIYDYEKEKNLSLSILCQDSGKEPRYTKQLLTIFIKDVNDNRPKFLRSFYRKSINEDQEKLKPFTKVQALDKDSDDFGKVKYSIGLKDRKYFSIDEISGEVRLANEIDRETKDFYNVSVIATDGGGLKDYSYIEI--SILDVNDNYPKLKSGSSMR--VNENLPVGSVVGYISVIDLDLGDNSKVEWTYDFLGNS-SSMLQIENCT--VYTSTVLDRESIEHLHILITMVDMGYPRLTSSATITVSVIDENDNIPK 2068
T+ +N A S++ +++ P G +Y II+ FRI S +G I + V DR E + +T+ K+ +P V I + DENDN+P F+ + + I E + + A D+D YS+ F+ I L+VKK + E + + L++ A D G T +L V V D+NDNPP+F + +++EN+ ++L + A D D G NA + Y S N + F++ S +G I LD+E S+ + + V A D + + + + V ++ND +P + ++ + EN + +K+ SD DS + K + ++Q S I ++ D E ++ + D+G P +TI I D NDN PKF S Y SI E+ K+ A D D ++ Y++ D F I SG + LA +DRE K Y++++ A D G S I I +++D+ND+ P + S SS+R V EN P + V I D D G N+ E T+ L N S+ ++N T + T LDRE + I + D G P L+S A + + VIDE+DN P+
Sbjct: 1210 LTVTENTANGSNILRVLASDPDAGANGRVTYSIISG-----NHGNAFRIDSTTGRITVVGVVDR------------------EALASYNLTISAKDSGVPPWVSTAFVAITVADENDNSPIFASNETSYGIDEGVSIGSRVAVVTATDRDEGSNAQVFYSIVRGDTSAFA--INAMNGVLTVKKEINRE--TVPTYTLTIRASDRGSPMMTSDKELTVVVNDVNDNPPVFNSQSYIGSVRENSAQSTSVLTVAADDSDVGANAVLRYSIISGND---EKRFKINSTSGVIMTTTPLDFEEKSQ--YGLEVTATDS---KYTAKTNVTIRVINLNDITPAFTQQNYTASVRENSPTSTSVVKVSASDRDSFGSLSYSIVGGKDSDKFSIDQ---RSGIISTADVLDRELVSLYAIQVRVTDAGNPPLSNLTWVTIKILDENDNSPKFDSSSYSSSILENSAPSSFSFKLAATDADEGTNARITYNLSRND--AFMIGASSGVITLAQPLDRENKSTYDLAIQARDHGTPPQASSITIRVTVIDINDHRPLINS-SSLRGSVRENQPKETHVMRILASDADTGLNA--ELTFSLLSNEHKSVFTLDNTTGDISTKVPLDREQQAVYTLRIGVADKGNPSLSSVADVIIDVIDEDDNCPR 1823 HSP 7 Score: 160.999 bits (406), Expect = 6.977e-40 Identity = 169/626 (27.00%), Postives = 287/626 (45.85%), Query Frame = 2
Query: 452 VVIVIEDENDNAPDXXXXXXXXXXXXND-ATQLDHNLPKALDKDCPIYGIKNYSLSGNKVEYF----SLKIRQFQPFLSVKKSFDFENPSEKQFNLSLNAIDNGGKSATLQLIVNVIDINDNPPIFQKKIVNVTIQENTTFPDAILKLNATDLDSGNNAQISYKFSSINRPIIRETFQLQSETGKIYLLKTLDYELYSEQNFDINVLAIDHGSPQLSDSCIIKVNVTDINDNSPVIEIV-HSQPIPENEQITDPALKLYVSDYDSIDNDVKCQAEKIGRRLKLEQVEKSSYFIYATEIYDYEKEKNLSLSILCQDSGKEPRYTKQLLTIFIKDVNDNRPKFLRSFYRKSINEDQEKLKPFTKVQALDKDSDDFGKVKYS-IGLKDRKYFSIDEISGEVRLANEIDRETKDFYNVSVIATDGGGLKDYSYIEISIL--DVNDNYPKLK-SGSSMRVNENLPVGSVVGYISVIDLDLGDNSKVEWTYDFLGNSSSMLQIE--NCTVYTSTVLDRESIEHLHILITMVDMGYPRLTSSATITVSVIDENDNIPKVIYPKTGSLVEEREMDHIAVNSPKYTTVLSIKSFDPDLGINGDVLYHILPSNGSQYFIINQTSGV--LKTTWIYD 2287
VVI ++DENDNAP+F +S+ +I EN A Q+ + A D+D YSL + ++ + +IR P ++ ++ + + ++A D GK T ++ V D+NDN P F + + E+ + +L A DLD G NA++SY S + F + S+ G I D E ++ ++ + + A D GSP S +++ + D+NDN PV ++ + E+ I + + SD D+ +N + G ++ + + + D+E+ + +L + D G P L I + D+NDN P F S Y+ + +E T+V A D+DS G + + I D F+ID +G + +A D E K Y+++V A D G Y +++I DVND+ P S S ++ E+ +GS V ++ DLD G ++E+ GN I+ + ++ S+ LDRE+ + + D G +SS +T+++ D NDN P P + E H + + + D D NGDV Y + S+ + F IN ++G+ LKT Y+
Sbjct: 56 VVIDVKDENDNAPEFPLNSYVFNIRENTPAAQV--AIVTATDRDSGTNAAITYSLFSGENKFMMNSKTGEIRTVTP---------LDHETKDSYTMRISAFD--GKHTTFVPLITVDDVNDNAPFFALSVYKTGVYEDVAVGSIVRQLTAVDLDVGINARLSYSLVSGDTSY----FTVDSQ-GVIRTKGAFDRE--TKASYQVALRAQDGGSPSRSGQATVEIEILDVNDNRPVFSSAQYTASVDEDVAIGAAMVTVTASDKDNGNNADLRYSFTSGNTNHAFTLDAVTGVVTVSRSLDFEQRSSYALGLSVTDRGSPPLTDTSHLLINVNDINDNPPVFSPSAYQSRV---KENTPAGTQVSATDRDSSTNGALVFGIIKGNDDGVFTIDGSTGIISIAKSPDYENKTRYDLTVQARDRGVPVKYDTAQVTIFIEDVNDHSPVFSPSNYSKQIPESTVIGSTVVTVTATDLDSGPRGRLEYRL-ISGNVKGAFNIDANSGSIRVSSELDRETTPSYSLQVEARDGGSTSRSSSTRVTIALQDINDNSPIFQGPYVFRVSESSSPGH---------QIGQVAATDADDSSNGDVRYAL--SDNTDVFSINTSTGLITLKTQLDYE 646 HSP 8 Score: 147.902 bits (372), Expect = 7.767e-36 Identity = 153/551 (27.77%), Postives = 248/551 (45.01%), Query Frame = 2
Query: 692 FENPSEKQFNLSLNAIDNGGK--SATLQLIVNVIDINDNPPIFQKKIVNVTIQENTTFPDA-ILKLNATDLDSGNNAQISYK-FSSINRPIIRETFQLQSETGKIYLLKTLDYELYSEQNFDINVLAIDHGSPQLSDSCIIKVNVTDINDNSPVIEI-VHSQPIPENEQITDPALKLYVSDYDSIDNDVKCQAEKIGRRLKLEQVEK-SSYF-------IYATEIYDYEKEKNLSLSILCQDSGKEPRYTKQLLTIFIKDVNDNRPKFLRSFYRKSINEDQEKLKPFTKVQALDKDSDDFGKVKYSIGLKDRKY-FSIDEISGEVRLANEIDRETKDFYNVSVIATDGGG--LKDYSYIEISILDVNDNYPKLK-SGSSMRVNENLPVGSVVGYISVIDLDLGDNSKVEWTYDFLGNSSSMLQIENCT--VYTSTVLDRESIEHLHILITMVDMGYPRLTSSATITVSVIDENDNIPKVIYPKTGSLVEEREMDHIAVNSPKYTTVLSIKSFDPDLGINGDVLYHILPSNGSQYFIINQTSGVLKTTWIYD 2287
F+ SE ++ L++ A D + ++++V D NDN P F I+ENT P A + + ATD DSG NA I+Y FS N+ F + S+TG+I + LD+E I+ H + + + V D+NDN+P + V+ + E D A+ V ++D DV A RL V +SYF I +D E + + +++ QD G R + + I I DVNDNRP F + Y S++ED V A DKD+ + ++YS + + F++D ++G V ++ +D E + Y + + TD G L D S++ I++ D+NDN P S RV EN P G+ +S D D N + + GN + I+ T + + D E+ + + D G P +A +T+ + D ND+ P V P S I ++ +TV+++ + D D G G + Y ++ N F I+ SG ++ + D
Sbjct: 28 FDRESESRYRLTVLAQDAANRCHKGRTVVVIDVKDENDNAPEFPLNSYVFNIRENT--PAAQVAIVTATDRDSGTNAAITYSLFSGENK------FMMNSKTGEIRTVTPLDHETKDSYTMRISAFDGKH------TTFVPLITVDDVNDNAPFFALSVYKTGVYE-----DVAVGSIVRQLTAVDLDVGINA-----RLSYSLVSGDTSYFTVDSQGVIRTKGAFDRETKASYQVALRAQDGGSPSRSGQATVEIEILDVNDNRPVFSSAQYTASVDEDVAIGAAMVTVTASDKDNGNNADLRYSFTSGNTNHAFTLDAVTGVVTVSRSLDFEQRSSYALGLSVTDRGSPPLTDTSHLLINVNDINDNPPVFSPSAYQSRVKENTPAGT---QVSATDRDSSTNGALVFGI-IKGNDDGVFTIDGSTGIISIAKSPDYENKTRYDLTVQARDRGVPVKYDTAQVTIFIEDVNDHSP-VFSPSNYS-------KQIPESTVIGSTVVTVTATDLDSGPRGRLEYRLISGNVKGAFNIDANSGSIRVSSELD 542 HSP 9 Score: 89.3521 bits (220), Expect = 7.469e-18 Identity = 89/331 (26.89%), Postives = 145/331 (43.81%), Query Frame = 2
Query: 566 ALDKDCPIYGIKNYSLSGNKVEYFSLKIRQFQPFLSVKKSFDFENPSEKQFNLSLNAIDNGGKSATLQLIVNVIDINDNPPIFQKKIVNVTIQENTTFPDAILKLNATDLDSGNNAQISYKFSSINRPIIRETFQLQSETGKIYLLKTLDYELYSEQNFDINVLAIDHGSPQLSDSCIIKVNVTDINDNSPVIEIVHSQ-PIPENEQITDPALKLYVSDYDSIDNDVKCQAEKIGRRLKLEQ-----VEKSSYFIYATEIYDYEKEKNLSLSILCQDSGKEPRYTKQLLTIFIKDVNDNRPKFLRSFYRKSINEDQEKLKPFTKVQALDKD 1540
A D+D +G +YS+ G K + I Q +S D E S + + N S + + ++D NDN P F + +I EN+ KL ATD D G NA+I+Y S + F + + +G I L + LD E ++ +D+ + A DHG+P + S I+V V DIND+ P+I + + EN+ +++ SD D+ AE L E ++ ++ I D E++ +L I D G + + I + D +DN P+F + Y +I+E + +V A D D
Sbjct: 1538 ASDRDS--FGSLSYSIVGGK-DSDKFSIDQRSGIISTADVLDRELVSLYAIQVRVTDAGNPPLSNLTWVTIKILDENDNSPKFDSSSYSSSILENSAPSSFSFKLAATDADEGTNARITYNLSR------NDAFMIGASSGVITLAQPLDRE--NKSTYDLAIQARDHGTPPQASSITIRVTVIDINDHRPLINSSSLRGSVRENQPKETHVMRILASDADT-----GLNAELTFSLLSNEHKSVFTLDNTTGDISTKVPLDREQQAVYTLRIGVADKGNPSLSSVADVIIDVIDEDDNCPRFQPTEYNVTISESLPRGASIVQVTARDID 1852
BLAST of Protocadherin alpha-2 vs. Ensembl Nematostella
Match: EDO41005 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S5N5]) HSP 1 Score: 193.356 bits (490), Expect = 7.030e-50 Identity = 168/589 (28.52%), Postives = 280/589 (47.54%), Query Frame = 2
Query: 563 KALDKDCPIYGIKNYSLSGNKVEYFSLKIRQFQPFLSVKKSFDFENPSEKQFNLSLNAIDNGGK--------SATLQLIVNVIDINDNPPIFQKKIVNVTIQENTTFPDAILKLNATDLDSGNNAQISYKFSSINRPIIRETFQLQSETGKIYLLKTLDYELYSEQNFDINVLAIDHGSPQLSDSCIIKVNVTDINDNSPVI-EIVHSQPIPENEQITDPALKLYVSDYDSIDNDVKCQ-----AEKIGRRLKLEQVEKSSYFIYATEIYDYEKEKNLSLSILCQDS-GKEPRYTKQLLTIFIKDVNDNRPKFLRSFYRKSINEDQEKLKPFTKVQALDKDSDDFGKVKYSI-GLKDRKYFSIDEISGEVRLANEIDRETKDFYNVSVIATDGGGL--KDYSYIEISILDVNDNYPK-LKSGSSMRVNENLPVGSVVGYISVIDLDLGDNSKVEWTYDFLGNSSSMLQIENCT--VYTSTVLDRESIEHLHILITMVDMGYPRLTSSATITVSVIDENDNIPKVIYPKTGSLVEEREMDHIAVNSPKYTTVLSIKSFDPDLGINGDVLYHILPSNGSQYFIINQTSGVL 2266
A+D+D + G Y ++ VE S I L + + D E S + +L + A D GG+ + T+ + +NV+D NDN P+ K ++I ENT+ +++ LN TD DSG NA + Y S + F + + TG + L K LD+E F + + IDHG P LS + V V ++NDN P + ++ I E + D A+ VS +D + C +G ++K + + A D E KN + S++ QDS P ++T+ + DVNDN P F R Y +++ED K++A+D D V YSI F +D ++GE++L ++++RE Y ++V + DGG + + + + I ++DVNDN P L ++R+ ENLP G V + D D N +VE+ +S +++ T + T+ LDRESI ++++T + + + ++ V V+D ND+ P S R +P +T+ +++ D D GIN +V Y ++ F IN T+G++
Sbjct: 561 SAVDRDKDLNGNIVYIITEGNVE-GSFIIGARSGLLQLNHTLDREVVS--KHSLRVTASDRGGEFMADGSSLNTTINVTINVLDSNDNIPVCDKVYYTISIPENTSVGQSLIHLNCTDQDSGENAHLLYHMVSGH-----SKFVVDNVTGIMSLNKLLDFE-EKPTVFTVAIEVIDHGRPPLSLVVFVNVTVDNVNDNYPSFGQDNYTFWISEGDFAVDHAIVGVVSAHDLDADSSNCPLCGKLQYTLGNSTGPFAIDKDTGVLRAVGSLDREGIKNYTFSVIAQDSIPNRPLVNVTMVTVNLLDVNDNDPVFDRDVYTANVSEDASPGLTVLKIRAVDNDLASNANVSYSIVSGNTGAAFHVDNVTGEIKLVSKLEREKITSYTLTVGSADGGAVPRRSTALVIIYVMDVNDNSPVCLHDTQTVRLLENLPAGHFVVKVVTTDPDEVHNGRVEYNL-----TSDAFRVDPFTGIITTTRALDRESIPAYNLMVTARNSNSSDMEVNCSVHVIVMDTNDHTP--------SFTMARYYISTPETTPVGSTLFRVRAVDGDDGINAEVRYTLMGE--ESLFRINYTTGIV 1125 HSP 2 Score: 149.828 bits (377), Expect = 1.762e-36 Identity = 179/643 (27.84%), Postives = 301/643 (46.81%), Query Frame = 2
Query: 446 VKVVIVIEDENDNAPDXXXXXXXXXXXXNDATQLDHNLPKALDKDCPIYGIKNYS-LSGNKVEYFSLKIRQFQPFLSVKKSFDFENPSEKQFNLSLNAIDNGGKSATLQ-----LIVNVIDINDNPPIFQKKIVNVTIQENTTFPDAILK-LNATDLDSGNNAQISYKFSSINRPIIRETFQLQSETGKIYLLKTLDYELYSEQNFDINVLAIDHGSPQLSDSCI------IKVNVTDINDNSPVIEIV-HSQPIPENEQITDPALKLYVSDYDSIDNDVKCQAEKIGRRLKLEQVEKSSYFIYATEIYDYEKEKNL-SLSILCQDSGKEPRYTKQLLTIFIKDVNDNRPKFLRSFYRKSINED----QEKLKPFTKVQALDKDSDD---FGKVKYSIGLKDRKYFSIDEISGEVRLANEIDRETKDFYNVSVIATDG---GGLKDYSYIEISILDVNDNYPKL-KSGSSMRVNENLPVGSVVGYISVIDLDLGDNSKVEWTYDFLGNSSSMLQIENCTVYTSTV--LDRESIEHLHILITMVDMGYPRLTSSATITVSVIDENDNIPKVIY-PKTGSLVEEREMDHIAVNSPKYTTVLSIKSFDPDLGINGDVLYHILPSNGSQYFIINQTSGVLKTTWIYD 2287
V + +++ DENDN+P FS + ++ I+EN+ A D D + +Y+ LS + Y KI ++ + D EN + F L + A D G +T++ ++V V+DINDN P F + N ++ E T P AIL ++A D D N I Y + N + +F + + +G + L TLD E+ S+ + + V A D G ++D + +NV D NDN PV + V ++ IPEN + + L +D DS +N + K V+ + + ++ D+E++ + +++I D G+ P + + + +VNDN P F + Y I+E + LD DS + GK++Y++G F+ID+ +G +R +DRE Y SVIA D L + + + +++LDVNDN P + + V+E+ G V I +D DL N+ V ++ GN+ + ++N T V L+RE I + + D G S+A + + V+D NDN P ++ +T L+E N P V+ + + DPD NG V Y++ S F ++ +G++ TT D
Sbjct: 413 VTITVMLRDENDNSPIFSRALYSSPIYENEPPGTFVIQVSANDSDIGSNAMVSYAVLSDAEGHYQYFKINAKNGTITTSRRLDRENIT--TFRLRVTASD-GAPLSTIRVSVVDVVVTVLDINDNSPEFVRPSYNFSVIE-TALPGAILGIISAVDRDKDLNGNIVYIITEGN---VEGSFIIGARSGLLQLNHTLDREVVSKHS--LRVTASDRGGEFMADGSSLNTTINVTINVLDSNDNIPVCDKVYYTISIPENTSVGQSLIHLNCTDQDSGEN-AHLLYHMVSGHSKF-VVDNVTGIMSLNKLLDFEEKPTVFTVAIEVIDHGRPPLSLVVFVNVTVDNVNDNYPSFGQDNYTFWISEGDFAVDHAIVGVVSAHDLDADSSNCPLCGKLQYTLG-NSTGPFAIDKDTGVLRAVGSLDREGIKNYTFSVIAQDSIPNRPLVNVTMVTVNLLDVNDNDPVFDRDVYTANVSEDASPGLTVLKIRAVDNDLASNANVSYSI-VSGNTGAAFHVDNVTGEIKLVSKLEREKITSYTLTVGSADGGAVPRRSTALVIIYVMDVNDNSPVCLHDTQTVRLLE---------NLPAGHFVVKVVTTDPDEVHNGRVEYNLT----SDAFRVDPFTGIITTTRALD 1029 HSP 3 Score: 144.821 bits (364), Expect = 6.848e-35 Identity = 173/669 (25.86%), Postives = 292/669 (43.65%), Query Frame = 2
Query: 299 DSGEIRITKVFDRDDVNNVCGPLGCCDKPSCEIVLDIIVTVIPKNERIPVKVVIV-IEDENDNAPDXXXXXXXXXXXXNDATQLDHNLPKALDKDCPIYGIKNYSL-SGNKVEYFSLKIRQFQPFLSVKKSFDFENPSEKQFNLSLNAIDNGG--KSATLQLIVNVIDINDNPPIFQKKIVNVTIQENTTFPDAILKLNATDLDSGNNAQISYKFSSINRPIIRETFQLQSETGKIYLLKTLDYELYSEQNFDINVLAIDHGSPQLSDSCIIKVNVTDINDNSPVIEIV-HSQPIPENEQITDPALKLYVSDYDSIDNDVKCQAEKIGRRLKLEQVEKSSYFIYATEIYDYEKEKNLSLSILCQDSG-KEPRYTKQLLTIFIKDVNDNRPKFLRSFYRKSINEDQEKLKPFTKVQALDKDSDDFGKVKYSI-GLKDRKYFSIDEISGEVRLANEIDRETKDFYNVSVIATDGG--GLKDYSYIEISILDVNDNYPKLKSGSSMRVN-ENLPVGSVVGYISVIDLDLGDNSKVEWTYDFLGNSSSMLQIENCTVYTSTVLDRESIEHLHILITMVDMGYPRLTSS-ATITVSVIDENDNIPKVIYPKTGSLVEEREMDHIAVNSPKYTTVLSIKSFDPDLGINGDVLYHILPSNGSQYFIINQTSGVLKT 2272
D+G +R DR+ + N + D IP + V +V V + D NDN P F +T ++ E+ + L +A+D D +YS+ SGN F + + +K E + L++ + D G + +T +I+ V+D+NDN P+ V + EN ++K+ TD D +N ++ Y +S + F++ TG I + LD E S +++ V A + S + +C + V V D ND++P + + PE + ++ D D N + + +G L ++ ++ + D E + L + +D G E + I + DVNDNRP F + Y ++ E Q V ALDKD + + YSI G F+I+ SG + +DRET D Y ++V+A+D G + + + I + DVNDN P + + + V EN P GS+V +S DLD G N++V ++ + + ++ N + LDRE+ D G P SS + + + DENDN P V P S+ +I+ N P ++ + + + D G +L+ I + YF I+ +GV+ T
Sbjct: 811 DTGVLRAVGSLDREGIKNYTFSVIAQDS-------------IPNRPLVNVTMVTVNLLDVNDNDPVFDRDVYTANVSEDASPGLTVLKIRAVDNDLASNANVSYSIVSGNTGAAFHVDNVTGE----IKLVSKLEREKITSYTLTVGSADGGAVPRRSTALVIIYVMDVNDNSPVCLHDTQTVRLLENLPAGHFVVKVVTTDPDEVHNGRVEYNLTS-------DAFRVDPFTGIITTTRALDRE--SIPAYNLMVTARNSNSSDMEVNCSVHVIVMDTNDHTPSFTMARYYISTPETTPVGSTLFRVRAVDGDDGIN-AEVRYTLMGEE-SLFRINYTTGIVTLVSSLDRENKAQYQLEVEARDRGIPESNANSTTILIRVGDVNDNRPTFTHAHYDGNVLEGQVGAV-AAIVVALDKDEEINADIVYSIIGGNTDNSFAINNKSGSIYTLLHLDRETTDRYILTVLASDRGEPAMNSSTNVTIHVNDVNDNKPNITNNPGVVVTRENTPPGSLVYILSASDLDEGSNARVAFSGYAVPDGKFSIK-PNGEIMVRDSLDREAQNRFVFYAMATDSGQPPFNSSMVSFDILIADENDNNP-VFDPVHYSV-------NISENGPSEEVIVQVNASERD---EGKLLFKISSGDPGGYFTIHNVTGVIST 1438 HSP 4 Score: 143.665 bits (361), Expect = 1.475e-34 Identity = 148/600 (24.67%), Postives = 272/600 (45.33%), Query Frame = 2
Query: 602 NYSL-SGNKVEYFSLKIRQFQPFLSVKKSFDFENPSEKQFNLSLN-------AIDNGGKSATLQLIVNVIDINDNPPIFQKKIVNVTIQENTTFPDAILKLNATDLDSGNNAQISYKFSSINRPIIRETFQLQSETGKIYLLKTLDYELYSEQNFDINVLAIDHGSPQLSDSCIIKVNVTDINDNSPVIEI-VHSQPIPENEQITDPALKLYVSDYD-SIDNDVKCQAEKIGRRLKLEQVEKSSYFIYATEIYDYEKEKNLSLSILCQDSGKEPRYTKQL-LTIFIKDVNDNRPKFLRSFYRKSINEDQEKLKPFTKVQALDKDSDDFGKVKYSIGLKDR----KYFSIDEISGEVRLANEIDRETKDFYNVSVIATDGGGLK----DYSYIEISILDVNDNYPK-LKSGSSMRVNENLPVGSVVGYISVIDL--DLGDN-------SKVEWTYDFLGNSSSMLQIENCTVYTSTVLDRESIEHLHILITMVDMG------YPRLTSSATITVSVIDENDNIP---KVIYPKTGSLVEEREMDHIAVNSPKYTTVLSIKSFDPDLGINGDVLYHILPSNGSQYFIINQTSGVLKTTWIYD 2287
NY++ SGN+ F + + + + + DFE ++ + N+S + I G S + VNV+D +D P F + +I EN +++++A DLD NA ++Y P+ F + + TG+I L +LD E +E + + +LA D + + VTD+NDN P+ + ++ + EN I +++ D D ++ + G + + S I D EK+ S++++ +++ + + +T+ ++D NDN P F R+ Y I E++ +V A D D V Y++ L D +YF I+ +G + + +DRE + + V A+DG L + +++LD+NDN P+ ++ + V E G+++G IS +D DL N VE ++ +G S +LQ+ + LDRE + + +T D G L ++ +T++V+D NDNIP KV Y + I N+ +++ + D D G N +LYH++ +G F+++ +G++ + D
Sbjct: 146 NYAIVSGNEDGIFDIDFNK--GVIRLARELDFEQMTQYKLNISASNPLTNDTVIPKNGLSNWTMVTVNVLDADDLPVRFNNYSYSASIPENAAMGSVVMQVHAKDLDKSINAPVTYAIDKETNPL--RMFNIANITGEITLNGSLDRETIAE--YRLRILAY---CTIYQDHTEVLITVTDVNDNIPLFTLPSYNTTVNENAAIGTYVIQVQAEDIDQGVNASFIYEIAYAGHEFVIGE---HSGIIIVNGTLDREKKDLYSITVIARETETSAGFHSNVTITVMLRDENDNSPIFSRALYSSPIYENEPPGTFVIQVSANDSDIGSNAMVSYAV-LSDAEGHYQYFKINAKNGTITTSRRLDRENITTFRLRVTASDGAPLSTIRVSVVDVVVTVLDINDNSPEFVRPSYNFSVIETALPGAILGIISAVDRDKDLNGNIVYIITEGNVEGSF-IIGARSGLLQLNHT-------LDREVVSKHSLRVTASDRGGEFMADGSSLNTTINVTINVLDSNDNIPVCDKVYYTIS-----------IPENTSVGQSLIHLNCTDQDSGENAHLLYHMV--SGHSKFVVDNVTGIMSLNKLLD 711 HSP 5 Score: 135.191 bits (339), Expect = 6.580e-32 Identity = 146/560 (26.07%), Postives = 251/560 (44.82%), Query Frame = 2
Query: 569 LDKD---CPIYGIKNYSLSGNKVEYFSLKIRQFQPFLSVKKSFDFENPSEKQFN-LSLNAIDNGGKSATLQLIVNVIDINDNPPIFQKKIVNVTIQENTTFPDAILKLNATDLDSGNNAQISYKFSSINRPIIRETFQLQSETGKIYLLKTLDYELYSEQNFDINVLAIDHGSPQLSDSCIIKVNVTDINDNSPV-IEIVHSQPIPENEQITDPALKLYVSDYDSIDNDVKCQAEKIGRRLKLE--QVEKSSYFIYATEIYDYEKEKNLSLSILCQDSGKEPRYTKQLLTIFIKDVNDNRPKFLRSFYRKSINEDQEKLKPFTKVQALDKDSDDFGKVKYSIGLKDRKYFSIDEISGEVRLANEIDRETKDFYNVSVIATDGG---GLKDYSYIEISILDVNDNYPKLKSGSSMRVNENLPVGSVVGYISVID-LDLGDNSKVEWTYDFLG-NSSSMLQIEN--CTVYTSTVLDRESIEHLHILITMVDMGYPRLTSSATITVSVIDENDNIPKVIYPKTGSLVEEREMDHIAVNSPKYTTVLSIKSFDPDLGINGDVLY 2206
LD D CP+ G Y+L GN F+ I + L S D E F+ ++ ++I N + VN++D+NDN P+F + + + E+ + +LK+ A D D +NA +SY S N F + + TG+I L+ L+ E + ++ + V + D G+ + ++ + V D+NDNSPV + + + EN +K+ +D D + N ++ L + +V+ + I T D E +L + ++S + + + D ND+ P F + Y S E +V+A+D D +V+Y++ + + F I+ +G V L + +DRE K Y + V A D G + + I I + DVNDN P + + N+ G V +++ LD + + Y +G N+ + I N ++YT LDRE+ + + + D G P + SS +T+ V D NDN P + +V RE N+P + V + + D D G N V +
Sbjct: 782 LDADSSNCPLCGKLQYTL-GNSTGPFA--IDKDTGVLRAVGSLDREGIKNYTFSVIAQDSIPNRPLVNVTMVTVNLLDVNDNDPVFDRDVYTANVSEDASPGLTVLKIRAVDNDLASNANVSYSIVSGNTG---AAFHVDNVTGEIKLVSKLEREKIT--SYTLTVGSADGGAVPRRSTALVIIYVMDVNDNSPVCLHDTQTVRLLENLPAGHFVVKVVTTDPDEVHNG------RVEYNLTSDAFRVDPFTGIITTTRALDRESIPAYNLMVTARNSNSSDMEVNCSVHVIVMDTNDHTPSFTMARYYISTPETTPVGSTLFRVRAVDGDDGINAEVRYTL-MGEESLFRINYTTGIVTLVSSLDRENKAQYQLEVEARDRGIPESNANSTTILIRVGDVNDNRPTF---THAHYDGNVLEGQVGAVAAIVVALDKDEEINADIVYSIIGGNTDNSFAINNKSGSIYTLLHLDRETTDRYILTVLASDRGEPAMNSSTNVTIHVNDVNDNKPNIT--NNPGVVVTRE------NTPPGSLVYILSASDLDEGSNARVAF 1315 HSP 6 Score: 117.857 bits (294), Expect = 1.358e-26 Identity = 172/693 (24.82%), Postives = 290/693 (41.85%), Query Frame = 2
Query: 302 SGEIRITKVFDRDDVNNVCGPLGCCDKPSCEIVLDIIVTVIPKNERIPVKVVIVIEDENDNAPDXXXXXXXXXXXXNDATQLDHNLPKA--------LDKDCPIYGIKNYSLSGNKVEYFSLKIRQFQPFLSVKKSFDFENPSEKQFNLSLNAIDNGGKSATLQLIVNVI--DINDNPPIFQKKIVNVTIQENTTFPDAILKLNATDLDSGNNAQISYKFSSINRPIIRETFQLQSETGKIYLLKTLDYELYSEQNFDINVLAIDHGSPQL-SDSCIIKVNVTDINDNSPVIEIVHSQPIPENEQITDPALKLYVSDYDSIDNDVKCQAEKI-----GRRLKLEQVEKSSYFIYATEIYDYEKEKNLSLSILCQDSGKEPRYTKQLLTIFIKDVNDNRPKFLRSFYRKSINEDQEKLKPFTKV---QALDKDSDDFGKVKYS-IGLKDRKYFSIDEISGEVRLANEIDRETKDFYNVSVIATDGGGLKDYSYI---EISILDVNDNYPKLKSGS-SMRVNENLPVGSVVGYISVIDLDLGDNSKVEWTYDFLGNSSSMLQIENCTVYTSTV--LDRESIEHLHILITMVDMGYPRLTSSATITVSVIDENDNIPKVIYPKTGSLVEEREMDHIAVNSPKYTTVLSIKSFDPDLGINGDVLYHI-----------LP-SNGSQYFIINQTSGVL 2266
+GEI++ +R+ + + +G D + +P+ R V+I + D NDN+P + + + +L NLP D D G Y+L+ + + ++ F ++ ++ D E S +NL + A ++ + V+VI D ND+ P F ++ E T + ++ A D D G NA++ Y F++ TG + L+ +LD E ++ + + V A D G P+ ++S I + V D+NDN P H + + + + + ++D D + A+ + G + S IY D E L++L D G+ + +TI + DVNDN+P + + +E P + V A D D +V +S + D K FSI + +GE+ + + +DRE ++ + +ATD G S + +I I D NDN P S+ ++EN P V+ ++ + D G K+ + G+ I N T ST LDRE + + IT D G P + +T+ V DEND P + + LV E HI + V SI + D D N + Y + LP S+GS+Y I T+G+L
Sbjct: 918 TGEIKLVSKLEREKITSYTLTVGSADGGA-----------VPR--RSTALVIIYVMDVNDNSP--------VCLHDTQTVRLLENLPAGHFVVKVVTTDPDEVHNGRVEYNLTSD-----AFRVDPFTGIITTTRALDRE--SIPAYNLMVTARNSNSSDMEVNCSVHVIVMDTNDHTPSFTMARYYISTPETTPVGSTLFRVRAVDGDDGINAEVRYTLMGE-----ESLFRINYTTGIVTLVSSLDRE--NKAQYQLEVEARDRGIPESNANSTTILIRVGDVNDNRPTFTHAH-----YDGNVLEGQVGAVAAIVVALDKDEEINADIVYSIIGGNTDNSFAINNKSGSIYTLLHLDRETTDRYILTVLASDRGEPAMNSSTNVTIHVNDVNDNKPNITNN---PGVVVTRENTPPGSLVYILSASDLDEGSNARVAFSGYAVPDGK-FSI-KPNGEIMVRDSLDREAQNRFVFYAMATDSGQPPFNSSMVSFDILIADENDNNPVFDPVHYSVNISENGPSEEVIVQVNASERDEG---KLLFKISS-GDPGGYFTIHNVTGVISTRKPLDREMVSRFDLTITAEDEGRPSRMALGYVTIFVNDENDFAP--VIEQCEQLVSVSENAHIG------SAVASINAVDKDDPSNTKITYSVGNSAFNITTQRLPFSSGSRYRGIIITAGLL 1553 HSP 7 Score: 112.849 bits (281), Expect = 4.126e-25 Identity = 143/537 (26.63%), Postives = 235/537 (43.76%), Query Frame = 2
Query: 767 QLIVNVIDINDNPPIFQKKIVNVTIQENTTFPDAILKLNATDLDSGNNAQISYKFSSINRPIIRETFQLQSETGKIYLLKTLDYE---LYSEQNFDINVLAID-HGSPQLSDSCIIKVNVTDINDNSPVI-EIVHSQPIPENEQITDPALKLYVSDYDSIDN-----DVKCQAEKIGRRLKLEQVEKSSYFIYATEIYDYEKEKNLSLSILCQDSG--KEPRYTKQLLTIFIKDVNDNRPKFLRSFYRKSINEDQEKLKPFTKVQALDKDSDDFGKVKYSIGLKD-RKYFSIDEISGEVRLANEIDRETKDFYNVSVIATDGGG--LKDYSY------IEISILDVNDNYPKL-KSGSSMRVNENLPVGSVVGYISVIDLDLGDNSKVEWTYDFLGNSSSMLQIENCTVYTS--TVLD-RESIEHLHILITMVDMGYPRLTSSATITVSVIDENDNIPKVIYPKTGSLVEERE--MDHIAVNSPKYTTVLSIKSFDPD---LGINGDVLYHILPSNGSQYFIINQTSGVLKTTWIYD 2287
++++ V D+NDN P+F N T+ EN ++++ A D+D G NA Y+ + F + +G I + TLD E LYS I V+A + S + I V + D NDNSP+ ++S PI ENE +++ +D D N V AE + K+ + I + D E L + D R + + + + D+NDN P+F+R Y S+ E + A+D+D D G + Y I + F I SG ++L + +DRE +++ V A+D GG + D S + I++LD NDN P K ++ + EN VG + +++ D D G+N+ + + + + S ++N T S +LD E + I ++D G P L+ + V+V + NDN P + E + +DH V V+S D D + G + Y + S G F I++ +GVL+ D
Sbjct: 310 EVLITVTDVNDNIPLFTLPSYNTTVNENAAIGTYVIQVQAEDIDQGVNASFIYEIAYAGHE-----FVIGEHSGIIIVNGTLDREKKDLYS-----ITVIARETETSAGFHSNVTITVMLRDENDNSPIFSRALYSSPIYENEPPGTFVIQVSANDSDIGSNAMVSYAVLSDAEGHYQYFKINAKNGT---ITTSRRLDRENITTFRLRVTASDGAPLSTIRVSVVDVVVTVLDINDNSPEFVRPSYNFSVIETALPGAILGIISAVDRDKDLNGNIVYIITEGNVEGSFIIGARSGLLQLNHTLDREVVSKHSLRVTASDRGGEFMADGSSLNTTINVTINVLDSNDNIPVCDKVYYTISIPENTSVGQSLIHLNCTDQDSGENAHLLY---HMVSGHSKFVVDNVTGIMSLNKLLDFEEKPTVFTVAIEVIDHGRPPLSLVVFVNVTVDNVNDNYPSFGQDNYTFWISEGDFAVDHAIVG------VVSAHDLDADSSNCPLCGKLQYTLGNSTGP--FAIDKDTGVLRAVGSLD 822 HSP 8 Score: 106.301 bits (264), Expect = 4.393e-23 Identity = 111/408 (27.21%), Postives = 184/408 (45.10%), Query Frame = 2
Query: 569 LDKDCPIYGIKNYSL-SGNKVEYFSLKIRQFQPFLSVKKSFDFENPSEKQFNLSLNAIDNG--GKSATLQLIVNVIDINDNPPIFQKKIVNVTIQENTTFPDAILKLNATDLDSGNNAQISYKFSSINRPIIRETFQLQSETGKIYLLKTLDYELYSEQNFDINVLAIDHGSPQLSDSCI-IKVNVTDINDNSPVIEIVH-SQPIPENEQITDPALKLYVSDYDSIDNDVKCQAEKIGRRLKLEQVEKSSYFIYATEIYDYEKEKNLSLSILCQDSGKEPRYTKQLLTIFIKDVNDNRPKFLRSFYRKSINEDQEKLKPFTKVQALDKDSDDFGKVKYSIG-------LKDRKYFSIDEISGEVRLANEIDRETKDFYNVSVIATDGGGLKDYSYIEISILDVNDNYP 1756
LDKD I YS+ GN F++ + S+ + + ++ L++ A D G +++ + ++V D+NDN P V +ENT + L+A+DLD G+NA+++ FS P F ++ G+I + +LD E ++ F +A D G P + S + + + D NDN+PV + VH S I EN + +++ S+ D K + G + V + I + D E L+I +D G+ R +TIF+ D ND P + S++E+ + A+DKD K+ YS+G + + S G + A +DRE +D YN++V A+DG + + I + I DVNDN P
Sbjct: 1198 LDKDEEINADIVYSIIGGNTDNSFAINNKSG----SIYTLLHLDRETTDRYILTVLASDRGEPAMNSSTNVTIHVNDVNDNKPNITNNPGVVVTRENTPPGSLVYILSASDLDEGSNARVA--FSGYAVP--DGKFSIKPN-GEIMVRDSLDRE--AQNRFVFYAMATDSGQPPFNSSMVSFDILIADENDNNPVFDPVHYSVNISENGPSEEVIVQVNASERDEGKLLFKISSGDPGGYFTIHNV---TGVISTRKPLDREMVSRFDLTITAEDEGRPSRMALGYVTIFVNDENDFAPVIEQCEQLVSVSENAHIGSAVASINAVDKDDPSNTKITYSVGNSAFNITTQRLPFSSGSRYRGIIITAGLLDRERQDNYNITVTASDGNHIATCNII-VRITDVNDNSP 1590 HSP 9 Score: 69.3218 bits (168), Expect = 9.564e-12 Identity = 76/284 (26.76%), Postives = 123/284 (43.31%), Query Frame = 2
Query: 668 LSVKKSFDFENPSEKQFNLSLNAIDNGG---KSATLQLIVNVIDINDNPPIFQKKIVNVTIQENTTFPDAILKLNATDLDSGNNAQISYKFSSINRPIIRETFQLQSETGKIYLLKTLDYELYSEQNFDINVLAIDHGSPQLSDSCIIKVNVTDINDNSPVIEIVHSQ-PIPENEQITDPALKLYVSDYDSIDN-----DVKCQAEKIG-RRLKLEQVEKSSYFIYATEIYDYEKEKNLSLSILCQDSGKEPRYTKQLLTIFIKDVNDNRPKFLRSFYRKSINE 1489
+ V+ S D E ++ +F A D+G S+ + + + D NDN P+F +V I EN + I+++NA++ D G ++ +K SS + F + + TG I K LD E+ S FD+ + A D G P + + V D ND +PVIE + EN I + D D N V A I +RL + I + D E++ N ++++ D + + I DVNDN P F ++ S++E
Sbjct: 1333 IMVRDSLDRE--AQNRFVFYAMATDSGQPPFNSSMVSFDILIADENDNNPVFDPVHYSVNISENGPSEEVIVQVNASERDEG---KLLFKISSGDPG---GYFTIHNVTGVISTRKPLDREMVSR--FDLTITAEDEGRPSRMALGYVTIFVNDENDFAPVIEQCEQLVSVSENAHIGSAVASINAVDKDDPSNTKITYSVGNSAFNITTQRLPFSSGSRYRGIIITAGLLDRERQDNYNITVTASDGN---HIATCNIIVRITDVNDNSPVFNQTTMNISLHE 1603 HSP 10 Score: 58.5362 bits (140), Expect = 1.563e-8 Identity = 58/181 (32.04%), Postives = 86/181 (47.51%), Query Frame = 2
Query: 614 SGNKVEYFSLKIRQFQPFLSVKKSFDFENPSEKQFNLSLNAIDNG--GKSATLQLIVNVIDINDNPPIFQKKIVNVTIQENTTFPDAILKLNATDLDSGNNAQISYKF--SSINRPIIRETFQLQSE-TGKIYLLKTLDYELYSEQNFDINVLAIDHGSPQLSDSCIIKVNVTDINDNSPV 1141
SG+ YF+ I +S +K D E S +F+L++ A D G + A + + V D ND P+ ++ V++ EN A+ +NA D D +N +I+Y S+ N R F S G I LD E + N++I V A D +C I V +TD+NDNSPV
Sbjct: 1420 SGDPGGYFT--IHNVTGVISTRKPLDREMVS--RFDLTITAEDEGRPSRMALGYVTIFVNDENDFAPVIEQCEQLVSVSENAHIGSAVASINAVDKDDPSNTKITYSVGNSAFNITTQRLPFSSGSRYRGIIITAGLLDRE--RQDNYNITVTASDGNHIA---TCNIIVRITDVNDNSPV 1591
BLAST of Protocadherin alpha-2 vs. Ensembl Nematostella
Match: EDO48237 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RKF4]) HSP 1 Score: 188.734 bits (478), Expect = 2.279e-48 Identity = 162/508 (31.89%), Postives = 239/508 (47.05%), Query Frame = 2
Query: 797 DNPPIFQKKIVNVTIQENTTFPDAILKLNATDLDSGNNAQISYKFSSINRPIIRETFQLQSETGKIYLLKTLDYELYSEQNFDINVLAIDHGSPQLSDSCIIKVNVTDINDNSPVIEI-VHSQPIPENEQITDPALKLYVSDYDSIDN-DVK-CQAEKIGRRLKLEQVEKSSYFIYATEIYDYEKEKNLSLSILCQDSGKEPRYTKQLLTIFIKDVNDNRPKFLRSFYRKSINEDQEKLKPFTKVQALDKDSDDFGKVKYSI-GLKDRKYFSIDEISGEVRLANEIDRETKDFYNVSVIATDGGG--LKDYSYIEISILDVNDNYPKLKSGS-SMRVNENLPVGSVVGYISVIDLDLGDNSKVEWTYDFLGNSSSMLQIENC-TVYTSTVLDRESIEHLHILITMVDMGYPRLTSSATITVSVIDENDNIPKVIYPKTGSLVEEREMDHIAVNSPKYTTVLSIKSFDPDLGINGDVLYHILPSNGS-QYFIIN-QTSGVLKTTWIYDT 2290
+NPP F + + ++ E+ + ++A+D DSG+N I Y S + F + TG I + LD E F V A D G P L + +NV D+NDN P+ E +++ IPE++ I D L + SD DS N +VK C G E S ++ D EK +L + QD G PR + I + DVND P+F + Y +I ED + T V+A D D G+V + I D +FSI+ I+GEVR+ ++D E +N+ V A D G L + + ++I+++DVNDN P+ S + EN VG + D D G N ++ T+ F+ N EN + LDRE + I D G P +A IT++++D NDN PK +E IA NS T+VL +K+ DPD G +V+Y I+ S+G + F IN Q L T Y+T
Sbjct: 15 NNPPQFSRLQEDASVSEDAEVGTVVATVSASDPDSGSNGMIRYSMSPSQNLMSATYFSIDQITGVITTKRGLDREFLDRHFF--RVKAEDGGEPSLEGYMDLTINVLDVNDNGPIFERNIYAADIPEDKSIGDFVLAVRASDADSGSNGEVKYCILNSDGDNSAFSIGEVSGAVTVMKKL-DREKVPTYTLQVQAQDQGNPPRSATVTVKITLLDVNDCTPQFSKKVYSATIREDVPVNQLVTTVRATDCDQGSNGEVFFEIVSGNDMNFFSINRINGEVRVKQKLDYEMIGVFNLLVTAQDKGQPFLYNQTTVDIALIDVNDNAPQFVSSHFQTMIPENYAVGQEFYRVQAYDKDHGTNGEI--TFSFMQNDLPFSINENTGGISIKEELDREKVPKFTFGIKARDKGVPFKEGTAQITITLLDINDNPPK--------FSQEEYHTSIAENSRWGTSVLQVKAIDPDSGPT-NVVYSIVSSSGHDRCFRINPQGLITLSCTLNYNT 508 HSP 2 Score: 164.851 bits (416), Expect = 5.303e-41 Identity = 154/578 (26.64%), Postives = 266/578 (46.02%), Query Frame = 2
Query: 563 KALDKDCPIYGIKNYSLSGNKVEYFSLKIRQFQPFLSVKKSFDFEN-PSEKQFNLSLNAIDNGG--KSATLQLIVNVIDINDNPPIFQKKIVNVTIQENTTFPDAILKLNATDLDSGNNAQISYKFSSINRPIIRETFQLQSETGKIYLLKTLDYELYSEQNFDINVLAIDHGSPQLSDSCIIKVNVTDINDNSPVIEIVHSQP-IPENEQITDPALKLYVSDYDSIDNDVKCQAEKIGRRLKLEQVEKSSYFIYATEIYDYEKEKNLSLSILCQDSGKEPRYTKQLLTIFIKDVNDNRPKFLRSFYRKSINEDQEKLKPFTKVQALDKDSDDFGKVKYSI--GLKDRKYFSIDEISGEVRLANEIDRETKDFYNVSVIATDGGGLKDYSYIEISILDVNDNYPKLKSGS-SMRVNENLPVGSVVGYISVIDLDLGDNSKVEWTYDFLGNSSSMLQIENCTVYTSTVLDRESIEHLHILITMVDMGYPRLTSSATITVSVIDENDNIPKVIYPKTGSLVEEREMDHIAVNSPKYTTVLSIKSFDPDLGINGDVLYHILP-SNGSQYFIINQTSGVLKT 2272
+A D D G Y + + + + I + ++V K D E P+ + L + A D G +SAT+ + + ++D+ND P F KK+ + TI+E+ + + ATD D G+N ++ ++ S N F + G++ + + LDYE+ F++ V A D G P L + + + + D+NDN+P H Q IPEN + ++ D D N + + L + +++ I E D EK + I +D G + +TI + D+NDN PKF + Y SI E+ +V+A+D DS V YSI + F I+ G + L+ ++ TK Y SV A+D G L + + +++ D N + P+ K S S V E+ +G+ V + D D G N+K+ ++ L S+ + + T+ LDRE ++ +T D G P+L + + + + + D NDN P + P + V E + V+ + + D D+G N ++Y +G F I+ T G+++T
Sbjct: 151 RASDADSGSNGEVKYCILNSDGDNSAFSIGEVSGAVTVMKKLDREKVPT---YTLQVQAQDQGNPPRSATVTVKITLLDVNDCTPQFSKKVYSATIREDVPVNQLVTTVRATDCDQGSNGEVFFEIVSGND---MNFFSINRINGEVRVKQKLDYEMIGV--FNLLVTAQDKGQPFLYNQTTVDIALIDVNDNAPQFVSSHFQTMIPENYAVGQEFYRVQAYDKDHGTNG-EITFSFMQNDLPFS-INENTGGISIKEELDREKVPKFTFGIKARDKGVPFKEGTAQITITLLDINDNPPKFSQEEYHTSIAENSRWGTSVLQVKAIDPDSGP-TNVVYSIVSSSGHDRCFRINP-QGLITLSCTLNYNTKHVYVFSVSASD-GMLSSTALVYVNVTDSNTHAPEFKRRSYSAEVKEDASLGTSVLTVLATDRDTGSNAKISYSIATLVPEFSVDETTG-VIKTAGSLDREKVDTYRFEVTATDHGIPQLKAKSFVYIHIADVNDNDPVFLKPSYEAKVRE--------DIRPGGRVIEVSASDADIGKNAQIIYSFASNGDGQGTFTIDSTQGIIRT 706 HSP 3 Score: 135.576 bits (340), Expect = 5.548e-32 Identity = 168/665 (25.26%), Postives = 286/665 (43.01%), Query Frame = 2
Query: 305 GEIRITKVFDRDDVNNVCGPLGCCDKPSCEIVLDIIVTVIPKNERI---PVKVVIVIEDENDNAPDXXXXXXXXXXXXNDATQLDHNLPKALDKDCPIYGIKNYSLSGNKVEYFSLKIRQFQPFLSVKKSFDFENPSEKQFNLSLNAIDNG--GKSATLQLIVNVIDINDNPPIFQKKIVNVTIQENTTFPDAILKLNATDLDSGNNAQISYKFSSINRPIIRETFQLQSETGKIYLLKTLDYELYSEQNFDINVLAIDHGSPQLSDSCIIKVNVTDINDNSPVIEI-VHSQPIPENEQITDPALKLYVSDYDSIDNDVKCQAEKIGRRLKLEQVEKSSYFIYATEIYDYEKEKNLSLSILCQDSGKEPRYTKQLLTIFIKDVNDNRPKFLRSFYRKSINEDQEKLKPFTKVQALDKDSDDFGKVKYSIGLKD--RKYFSIDEISGEVRLANEIDRETKDFYNVSVIATDGGGLKDYSYIEISIL--DVNDNYPKL-KSGSSMRVNENLPVGSVVGYISVIDLDLGDNSKVEWTYDFLGNSSSMLQIENCTVYTSTVLDRESIEHLHILITMVDMGYPRLTSSATITVSVIDENDNIPKVIYPKTGSLVEEREMDHIAVNSPKYTTVLSIKSFDPDLGINGDVLYHILPSNGSQYFIINQTSGVL 2266
GE+R+ + D + + V +++VT K + V I + D NDNAP F S F I EN A + +A DKD G +S N + + I + +S+K+ D E +F + A D G K T Q+ + ++DINDNPP F ++ + +I EN+ + ++L++ A D DSG + +S ++ F++ + G I L TL+Y + V ++ LS + ++ VNVTD N ++P + +S + E+ + L + +D D+ N + I + V++++ I D EK + D G K + I I DVNDN P FL+ Y + ED +V A D D ++ YS + F+ID G +R +DRET Y ++V+ATD G + +++ ++ DV D+ P K + V E+ P S V + DL + + ++ GNS + I T T++ + +T+ P T + T+ V + D NDN P + V+E ++ A +Y I ++DPD ++ + + ++ N ++ +N TSG L
Sbjct: 289 GEVRVKQKLDYEMIG----------------VFNLLVTAQDKGQPFLYNQTTVDIALIDVNDNAPQFVSSHFQTMIPENYAVGQEFYRVQAYDKDHGTNGEITFSFMQNDLPF---SINENTGGISIKEELDREK--VPKFTFGIKARDKGVPFKEGTAQITITLLDINDNPPKFSQEEYHTSIAENSRWGTSVLQVKAIDPDSGPTNVV---YSIVSSSGHDRCFRINPQ-GLITLSCTLNYNTK-----HVYVFSVSASDGMLSSTALVYVNVTDSNTHAPEFKRRSYSAEVKEDASLGTSVLTVLATDRDTGSNAKI--SYSIATLVPEFSVDETTGVIKTAGSLDREKVDTYRFEVTATDHGIPQLKAKSFVYIHIADVNDNDPVFLKPSYEAKVREDIRPGGRVIEVSASDADIGKNAQIIYSFASNGDGQGTFTIDSTQGIIRTLKPLDRETIPEYELTVVATDQGTPPGQASVKVKVILEDVKDSPPLFEKPLYEVTVPEDTPPRSPVITVKAKSQDLSPETGMMYSI-VRGNSPQVFDINPNTGAIQTLMKLDYETQSEYRLTVRATLSPFFTET-TVMVYLKDINDNTPVLEAFHMNINVQEGKVPPEA----RY----KIPAYDPD--VSDKLTFKVMEGNAKEWVTLNATSGEL 909
BLAST of Protocadherin alpha-2 vs. Ensembl Nematostella
Match: EDO35412 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SLK9]) HSP 1 Score: 181.8 bits (460), Expect = 2.703e-46 Identity = 186/631 (29.48%), Postives = 301/631 (47.70%), Query Frame = 2
Query: 458 IVIEDENDNAPDXXXXXXXXXXXXNDATQLDHNLPKALDKDCPIYGIKNYSLSGNKVEYFSL-KIRQFQPFLSVKKSFDFENPSEKQFNLSLNAIDNG--GKSATLQLIVNVIDINDNPPIFQKKIV--------NVTIQENTTFPDAILKLNATDLDSGNNAQISYKFSSINRPIIRETFQLQSETGK-IYLLKTLDYELYSEQNFDINVLAIDHGSPQLSDSCIIKVNVTDINDNSPVIEI-VHSQPIPENEQITDPALKLYVSDYDSIDNDVKCQAEKIGRRLKLEQVEKSSYFIYATEIYDYEKEKNLSLSILCQDSGKEPRYTKQLLTIFIKDVNDNRPKFLRSFYRKSINEDQEKLKPFTKVQALDKDSDDFGKVKYSIGLKDRK---YFSIDEISGEVRLANEIDRETKDFYNVSVIATDGGG--LKDYSYIEISILDVNDN----YPKLKSGSSMRVNENLPVGSVVGYISVIDLDLGDNSKVEWTYDFL-GNSSSMLQIENCTVYTSTV--LDRESIEHLHILITMVDMGYPRLTSSATITVSVIDENDNIPKVIYPKTGSLVEEREMDHIAV--NSPKYTTVLSIKSFDPDLGINGDVLYHILPSNGSQYFIINQTSGVLK 2269
I I DEND+AP F+++S+ SI EN + A D+D G Y++ + ++ S+ + + K++ DFE + FN+ A D G K+ + +NV+D NDN P Q KI EN+ I + TD DS N+Q K ++ + F+++ I L K LD EL N +NV D G P S + ++VTD+NDNSP ++ I E Q L+L +D D DN + G L QV+ S + + D E+ +++++I QD G P+ +T+ I D NDN+P+F++S Y+ +I+E +V A D DS D G++ Y I D + F ++ +G + +++DRETK Y+ +V+A D G L +E++I D+NDN YP S M EN P G ++ ++ D D G N+ + +YD + GN++ I++ T ST+ LD E E ++I+ D G +A + V+V+++ DN+P +Y EM + V N PK T V + + D NG + Y I+ + + F+++ T G++K
Sbjct: 194 ITILDENDHAPVFTQNSYLGSIAENTKPGVSILRVSAADRDSGSNGDIKYAIDWDAIQSNSIFDLDSSTGVIRTKQNLDFEVKNSYTFNVI--ASDGGVPSKNDLATVTINVLDTNDNSP--QLKITYLPPHNGDKAIRSENSLINTNIAYILVTDKDSNTNSQTELKITNGDD---EGCFKVEFLGFYFIQLQKPLDRELVPFYNLTLNV--TDKGVPSRSTLGFVLIDVTDVNDNSPAFTSNAYTANISELAQNGSYVLQLNATDPDEGDNGTVSYSITGGNDLGWFQVDFQSGLVTTAKPLDREQVSSVTITITAQDHGSAPKTGSTTVTVTIIDGNDNKPRFMKSSYKGTISEGASIGATVLQVSATDVDSGDNGRITYEISSSDAQVNGLFELNTQTGVLWTKSQLDRETKSLYSFTVLAKDHGDPQLMSSVKVELTISDINDNAPVFYPVEYFASIM---ENEPPGKLL-QVTATDADEGTNAVI--SYDIIGGNNNGNFSIDSSTGVISTLASLDHEVEEFFSLIISAKDGGNKYAAKTAVVNVTVLNKADNLPVFLY----------EMYNFTVYENVPKGTLVGRVYATTKDK--NGSISYAIVSGDPTNLFLVDSTGGIIK 797 HSP 2 Score: 145.206 bits (365), Expect = 5.393e-35 Identity = 153/547 (27.97%), Postives = 250/547 (45.70%), Query Frame = 2
Query: 713 QFNLSLNAIDNGGKSATLQLIVNVIDINDNPPIFQKKIVNVTIQE----NTTFPDAILKLN-ATDLDSGNNAQISYKFSSINRPIIRETFQLQSETGKIYLL---KTLDYELYSEQNFDINVLAIDHGSPQLSDSCIIKVNVTDINDNSPVI-EIVHSQPIPENEQITDPALKLYVSDYDSIDN-DVKCQAEKIG-RRLKLEQVEKSSYFIYATEIYDYEKEKNLSLSILCQDSGKEPRYTKQLLTIFIKDVNDNRPKFLRSFY-----RKSINEDQEKLKP-FTKVQALDKDSDDFGKVKYSIGLKDRKYFSIDEISG--EVRLANEIDRETKDFYNVSVIATDGG--GLKDYSYIEISILDVNDNYPKLKSGS-SMRVNENLPVGSVVGYISVIDLDLGDNSKVEWTYDFLGNSSSMLQI--ENCTVYTSTVLDRESIEHLHILITMVDMGYPRLTSSATITVSVIDENDNIPKVIYPK-TGSLVEEREMDHIAVNSPKYTTVLSIKSFDPDLGINGDVLYHILPSNG--SQYFIINQTSGVLKT 2272
Q +L L ++ + ++Q V V DINDN P F + I+E NTT P +N ATD D+GNN + Y +S + TG + K LD E + + +N+ A D G+P L C+I + + D ND++PV + + I EN + L++ +D DS N D+K + + + ++ S+ I + D+E + + + +++ D G + +TI + D NDN P+ ++ K+I + + + DKDS+ + + I D + E G ++L +DRE FYN+++ TD G ++ I + DVNDN P S + + ++E GS V ++ D D GDN V ++ GN Q+ ++ V T+ LDRE + + I IT D G T S T+TV++ID NDN P+ + G++ E + TVL + + D D G NG + Y I S+ + F +N +GVL T
Sbjct: 64 QISLQLRTLNPSNQPISVQ--VQVDDINDNEPRFPTLYYTLRIRESMDVNTTNP-----INTATDPDAGNNGTVDYTIASGDNTATFSLGTTACPTGSTLCVITKKPLDRE--TTDFYQLNITATDRGTPALMGYCLINITILDENDHAPVFTQNSYLGSIAENTKPGVSILRVSAADRDSGSNGDIKYAIDWDAIQSNSIFDLDSSTGVIRTKQNLDFEVKNSYTFNVIASDGGVPSKNDLATVTINVLDTNDNSPQLKITYLPPHNGDKAIRSENSLINTNIAYILVTDKDSNTNSQTELKITNGDDEGCFKVEFLGFYFIQLQKPLDRELVPFYNLTLNVTDKGVPSRSTLGFVLIDVTDVNDNSPAFTSNAYTANISELAQNGSYVLQLNATDPDEGDNGTVSYSITG-GNDLGWFQVDFQSGLVTTAKPLDREQVSSVTITITAQDHGSAPKTGSTTVTVTIIDGNDNKPRFMKSSYKGTISEGASIG---------ATVLQVSATDVDSGDNGRITYEISSSDAQVNGLFELNTQTGVLWT 591 HSP 3 Score: 131.339 bits (329), Expect = 8.426e-31 Identity = 136/525 (25.90%), Postives = 230/525 (43.81%), Query Frame = 2
Query: 770 LIVNVIDINDNPPIFQKKIVNVTIQENTTFPDAILKLNATDLDSGNNAQISYKFSSINRPIIRETFQLQSETGKIYLLKTLDYELYSEQNFDINVLAIDHGSPQLSDSCIIKVNVTDINDNSPVI-EIVHSQPIPENEQITDPALKLYVSDYDSIDNDVKCQAEKIGRRLKLEQVEKSSYFIYATEIYDYEKEKNLSLSILCQDSGKEPRYTKQLLTIFIKDVNDNRPKFLRSFYRKSINEDQEKLKPFTKVQALDKDSDDFGKVKYSI-GLKDRKYFSIDEISGEVRLANEIDRET----KDFYNVSVIATDGGG--LKDYSYIEISILDVNDNYPKLKSGSSMRVNENLPVGSVVGYISVIDLDLGDNSKVEWT-------YDFLGNSSSMLQI-----ENCTVYTSTVLDRESIEHLHILITMVDMGYPRLTSSATITV---SVIDENDNIPKVIYPKTGSLVEEREMDHIAVNSPKYTTVLSIKSFDPDLGINGDVLYHILPSNGSQYFIINQTSGVLKTT 2275
+IV V D+NDN P+F + + +T+ E + + ++ A D D G+NA+ Y S + F + S TG+++L KTLD E S ++++ V A D + L + I++ V D ND PV E ++ I E+ I + L SD D N + + G + VE ++ + + D+E + L+I QD G P + +T+ + DVNDN P F ++ E+ P + A D+D+ + +S+ K FS++ + E+ ID ET +D + + V+ATD G L I + + D NDN P S + +L V + I+ D D N KV ++ Y L S+ LQ+ +N T+Y + I D G P + ++V I Y GS+ E N T+V+++ + P +NG++ Y++ + F + +++GV+KTT
Sbjct: 1145 VIVTVTDLNDNAPVFSRAVYAITVSELSLPGSPVFRIKAMDADEGDNAKFFYSLVSGTG---MDKFFINSSTGELHLSKTLDRETTS--SYNLVVKATDASNANLYSTAKIEITVGDSNDQRPVFPESDYTVNITEDALIGSLVINLNASDKDIGQNGLIKYSISNGNLAAMFDVESATGRLIVAKSLDFETTQLYELTITAQDHGLIPLSSTVNVTVNVLDVNDNAPLFPTQPVTLTVRENVNTGFPVGRCTASDRDTGTNAHIAFSMYSQTPSKTFSVNSATCEITTIAAIDLETMPAGRDSFQLVVMATDQGSPKLSTRKSITVQVTDENDNSPGFVSPPAAAAGSSLNVMT----ITAEDPDRNSNGKVTYSIISGNNGYFNLHPSTGQLQMIHQIPDNPTIY-------------QLTIQASDGGQPSRQTQTVVSVFKEGPIGGGPTFSSADY--QGSVTE---------NKVAGTSVVTVLAAYPQSSLNGNIEYYLTSDSSKGGFEVVKSTGVVKTT 1636 HSP 4 Score: 127.102 bits (318), Expect = 1.976e-29 Identity = 157/576 (27.26%), Postives = 258/576 (44.79%), Query Frame = 2
Query: 416 TVIPKNERIPVKVVIVIEDENDNAPDXXXXXXXXXXXXNDATQLDHNLP-------KALDKDCPIYGIKNYSL-SGNKVEYFSLKIRQFQPFLSVKKSFDFENPSEKQFNLSLNAID--NGGKSATLQLIVNVIDINDNPPIFQKKIVNVTIQENTTFPDAILKLNATDLDSGNNAQISYKFSSINRPIIRETFQLQSETGKIYLLKTLDYELYSEQNFDINVLAIDHGSPQLSDSCIIKVNVTDINDNSPVIEIVHSQPIP----ENEQITDPALKLYVSDYDSIDNDVKCQAEKIGRRLKLEQVEKSSYFIYATEIYDYEK----EKNLSLSILCQDSGKEPRYTKQLLTIFIKDVNDNRPKFLR---SFYRKSINEDQEKLKPFTKVQALDKDSDDFGKVKYSIGLKDRKYFSIDEISGEVRLANEIDRETKDFYNVSVIATDGGGLKDYSYIEISILDVN--DNYPKLKSGS-SMRVNENLPVGSVVGYISVIDLDLGDNSKVEWTYDFLGNSSSMLQIE----NCTVYTSTVLDRESI-EHLHILITMVDMGYPRL-TSSATITVSVIDEN 2053
T I +++ I V++ + D NDNAP FS + + I T + +LP KA+D D YSL SG ++ F + + LS K+ D E S +NL + A D N +T ++ + V D ND P+F + V I E+ ++ LNA+D D G N I Y S+ N + F ++S TG++ + K+LD+E + Q +++ + A DHG LS + + VNV D+NDN+P+ +QP+ EN P + SD D+ N + K V ++ I D E + L ++ D G T++ +T+ + D NDN P F+ + S+N + A D D + GKV YSI + YF++ +G++++ ++I + Y +++ A+DGG + +S+ P S V EN G+ V + N +E+ +L + SS E V T+ +DRE + ++++ VD P TSSAT+T++V D N
Sbjct: 1136 TTIKRDKAI---VIVTVTDLNDNAPVFSRAVYAI-------TVSELSLPGSPVFRIKAMDADEGDNAKFFYSLVSGTGMDKFFINSSTGELHLS--KTLDRETTSS--YNLVVKATDASNANLYSTAKIEITVGDSNDQRPVFPESDYTVNITEDALIGSLVINLNASDKDIGQNGLIKYSISNGN---LAAMFDVESATGRLIVAKSLDFE--TTQLYELTITAQDHGLIPLSSTVNVTVNVLDVNDNAPLFP---TQPVTLTVRENVNTGFPVGRCTASDRDTGTNAHIAFSMYSQTPSKTFSVNSATCEITTIAAIDLETMPAGRDSFQLVVMATDQGSPKLSTRKSITVQVTDENDNSPGFVSPPAAAAGSSLN--------VMTITAEDPDRNSNGKVTYSIISGNNGYFNLHPSTGQLQMIHQI-PDNPTIYQLTIQASDGGQPSRQTQTVVSVFKEGPIGGGPTFSSADYQGSVTENKVAGTSVVTVLAAYPQSSLNGNIEY---YLTSDSSKGGFEVVKSTGVVKTTRGIDREGMGASFNLVVYAVDKQGPSARTSSATVTITVQDVN 1677 HSP 5 Score: 116.701 bits (291), Expect = 3.047e-26 Identity = 139/508 (27.36%), Postives = 221/508 (43.50%), Query Frame = 2
Query: 263 SFTKFNQYFRISDSGEIRITKVFDRDDVNNVCGPLGCCDKPSCEIVLDIIVTVIPKNERIPVKVVIVIEDENDNAPDXXXXXXXXXXXXNDA--TQLDHNLPKALDKDCPIYGIKNYSLS-GNKVEYFSLKIRQFQPFLSVKKSFDFENPSEKQFNLSLNAIDNG--GKSATLQLIVNVIDINDNPPIFQKKIVNVTIQE--NTTFPDAILKLNATDLDSGNNAQISYKFSSINRPIIRETFQLQSETGKIYLLKTLDYELY--SEQNFDINVLAIDHGSPQLSDSCIIKVNVTDINDNSPVIEIVHSQPIPENEQITDPALKLYVSDYDSIDNDVKCQAEKIGRRLKLEQVEKSSYFIYATEIYDYEKEKNLSLSILCQDSGKEPRYTKQLLTIFIKDVNDNRPKFLRSFYRKSINEDQEKLKPFTKVQALDKDSDDFGKVKYSIGLKDRK-YFSIDEISGEVRLANEIDRETKDF-YNVSVIATDGGG---LKDYSYIEISILDVN 1744
S T +++F S +GE+ ++K DR+ ++ + D + N K+ I + D ND P S DA L NL A DKD G+ YS+S GN F ++ + L V KS DFE + + + L++ A D+G S+T+ + VNV+D+NDN P+F + V +T++E NT FP + + A+D D+G NA I++ S P +TF + S T +I + +D E +F + V+A D GSP+LS I V VTD NDNSP P + + + D D N + G + +I D L+I D G+ R T+ ++++F + P F + Y+ S+ E++ V A S G ++Y + K F + + +G V+ IDRE +N+ V A D G + + I++ DVN
Sbjct: 1200 SGTGMDKFFINSSTGELHLSKTLDRETTSSYNLVVKATDASNA-------------NLYSTAKIEITVGDSNDQRP-VFPESDYTVNITEDALIGSLVINL-NASDKDIGQNGLIKYSISNGNLAAMFDVESATGR--LIVAKSLDFE--TTQLYELTITAQDHGLIPLSSTVNVTVNVLDVNDNAPLFPTQPVTLTVRENVNTGFP--VGRCTASDRDTGTNAHIAFSMYS-QTP--SKTFSVNSATCEITTIAAIDLETMPAGRDSFQLVVMATDQGSPKLSTRKSITVQVTDENDNSPGF----VSPPAAAAGSSLNVMTITAEDPDRNSNGKVTYSIISGNNGYFNLHPSTGQLQMIHQIPD--NPTIYQLTIQASDGGQPSRQTQTVVSVFKEGPIGGGPTFSSADYQGSVTENKVAGTSVVTVLAAYPQSSLNGNIEYYLTSDSSKGGFEVVKSTGVVKTTRGIDREGMGASFNLVVYAVDKQGPSARTSSATVTITVQDVN 1677 HSP 6 Score: 112.849 bits (281), Expect = 4.343e-25 Identity = 181/755 (23.97%), Postives = 321/755 (42.52%), Query Frame = 2
Query: 41 FYD*NFLMMPTTMQILPSMLIVSFVLISVISADIFTARFTIPDNNARHSSV---GNIISKLPSRFP-RGSYQIITRRSSFTKFNQYFRIS-DSGEIRITKVFDRDDVNNVCGPLGCCDKPSCEIVLDIIVTVIPKNERIPVKVVIVIEDENDNAPDXXXXXXXXXXXXNDATQLDHNLPKALDKDCPIYGIKNYSLSGNKVEYFSL-KIRQFQPFLSVKKSFDFENPSEKQFNLSLNAIDNGGKS--ATLQLIVNVIDINDNPPIFQKKIVNVTIQENTTFPDAILKLNATDLDSGNNAQISYKFSSINRPIIRETFQLQSETGKIYLLKTLDYELYSEQNFDINVLAIDHGSPQLSDSCIIKVNVTDINDNSPV-IEIVHSQPIPENEQITDPALKLYVSDYDSIDNDVKCQAEKIGRRLKLEQVEKSSYFIYATEIYDYEKEKNLSLSILCQDSGKEPRYTKQLLTIFIKDVNDNRPKFLRSFYRKSINEDQEKLKPFTKVQALDKDSDDFGKVKYSIGLKDRKYFSIDEISGEVRLANEIDRETKDFYNVSVIATDGGGLKDYSYIEISILDVNDNYPKLKSGSSM-RVNENLPVGSVVGYISVIDLDLGDNSKVEWTYDFLGNSSSMLQI-ENCTVYTSTVLDRESIEHLHILITMVDMGYPRLTSSATITVSVIDENDNIPKVIYPKTGSLVEEREMDHIAVNSPKYTTVLSIKSFDPDLGINGDVLYHILPSNGSQYFIINQTSGVLKT 2272
FY+ L + T + +PS + FVLI V + + FT A S + G+ + +L + P G ++ + +F++ SG + K DR+ V++V + D S PK V V I+ D NDN P F +SS+ +I E + A D D G Y +S + + L ++ L K D E ++ ++ ++ A D+G +++++ + + DINDN P+F +I EN P +L++ ATD D G NA ISY N F + S TG I L +LD+E+ E+ F + + A D G+ + + ++ V V + DN PV + +++ + EN ++Y + D N A G L V+ + I D E++ L+++ + +P + + I + D NDN P+F S I+ + A+D D+ G V+Y + I+ SG ++LA ++ + Y V V+A+D G +S + I I ++ PK S + V + P+ Y+ +D D G N ++ ++ GN + I +Y L + +++ D G P ++S +T+ + D ND+ + ++ V +A NS T V ++ + D D++Y ++ S +F ++ SG + T
Sbjct: 390 FYN---LTLNVTDKGVPSRSTLGFVLIDVTDVNDNSPAFTSNAYTANISELAQNGSYVLQLNATDPDEGDNGTVSYSITGGNDLGWFQVDFQSGLVTTAKPLDREQVSSVTITITAQDHGSA-----------PKTGSTTVTVTII--DGNDNKPRFMKSSYKGTISEGASIGATVLQVSATDVDSGDNGRITYEISSSDAQVNGLFELNTQTGVLWTKSQLDRE--TKSLYSFTVLAKDHGDPQLMSSVKVELTISDINDNAPVFYPVEYFASIMENEP-PGKLLQVTATDADEGTNAVISYDIIGGNN---NGNFSIDSSTGVISTLASLDHEV--EEFFSLIISAKDGGNKYAAKTAVVNVTVLNKADNLPVFLYEMYNFTVYENVPKGTLVGRVYATTKDK--NGSISYAIVSGDPTNLFLVDSTGGIIKINGDMDREEKAQYLLAVIARVGTVKPLSAQATVNIEVLDRNDNAPQFSTSSVIVDIDGTWLVGQVVYNAAAVDLDAGKNGLVRYQLTSNAEGLLWINSTSGVIKLARKLTDGDETQYTVQVLASDSGSPPQHSTMTIHITLSINHPPKFTLSSYVTHVLASQPLSYQFFYVVAVDQDSGKNGQLFYSIP-QGNEEGLFGIFPGGKLYIRKSLLQALKGSYDLIVRATDGGVPSFSASVPVTIYIQDSNDH--RSLF------VNNTFRFAVAENSSPGTLVGTLVAHALDHSRTKDIVYSLISS--ESHFAVDVRSGQITT 1107 HSP 7 Score: 70.0922 bits (170), Expect = 5.292e-12 Identity = 69/272 (25.37%), Postives = 121/272 (44.49%), Query Frame = 2
Query: 1493 QEKLKPFTKVQALDKDSDDFGKVKYSIGLKDRKYFSIDEISGEVRLANEIDRETKDFYNVSVIATDGGGLKDYSYIEISILDVNDNYPKLKSGS-SMRVNENLPVGSVVGYISVIDLDLGDNSKVEWTYDFLGNSSSM-LQIENC------TVYTSTVLDRESIEHLHILITMVDMGYPRLTSSATITVSVIDENDNIPKVIYPKTGSLVEEREMDHIAVNSPKYTTVLSIKSFDPDLGINGDVLYHI----LPSNGSQYFIINQTSGVLKT 2272
QE+ P T V +D S G K F + +G + IDRET ++ + + +++ + D+NDN P+ + ++R+ E++ V + + D D G+N V++T N+++ L C V T LDRE+ + + IT D G P L I ++++DEND+ P + + IA N+ ++L + + D D G NGD+ Y I + SN F ++ ++GV++T
Sbjct: 17 QEEQPPGTYVGKVDGASAFEGS---------PKQFGFNSNTGVISTTARIDRETTTQISLQLRTLNPS--NQPISVQVQVDDINDNEPRFPTLYYTLRIRESMDVNTTNPINTATDPDAGNNGTVDYTIASGDNTATFSLGTTACPTGSTLCVITKKPLDRETTDFYQLNITATDRGTPALMGYCLINITILDENDHAPV--------FTQNSYLGSIAENTKPGVSILRVSAADRDSGSNGDIKYAIDWDAIQSN--SIFDLDSSTGVIRT 267
BLAST of Protocadherin alpha-2 vs. Ensembl Medaka
Match: pcdh9 (protocadherin 9 [Source:NCBI gene;Acc:101156238]) HSP 1 Score: 228.024 bits (580), Expect = 4.250e-61 Identity = 204/675 (30.22%), Postives = 331/675 (49.04%), Query Frame = 2
Query: 293 ISDSGEIRITKVFDRDDVNNVCGPLGCCDKPSCEIVLDIIVTVIPKNERIPVKVVIVIEDENDNAPDXXXXXXXXXXXXNDATQLDHNLPKALDKDCPIYGIKNYSLSGNKVEYFSLKIRQFQ-----PFLSVKKSFDFENPSEKQFNLSLNAIDNGG---KSATLQLIVNVIDINDNPPIFQKKIVNVTIQENTTFPDAILKLNATDLDSGNNAQISYKFSSINRPIIRETFQLQSETGKIYLLKTLDYELYSEQNFDINVLAIDHGSPQLSDSCIIKVNVTDINDNSPVIEIVH-SQPI------PENEQITDPALKLYVSDYDS-IDNDVKCQAEKIGRRLKLEQVEKSSYFIYATEIYDYEKEKNLSLSILCQDSGKEPRYTKQLLTIFIKDVNDNRPKFLRSFYRKSINEDQEKLKPFTKVQALDKDSDDFGKVKYSIGLKDRKYFSIDEISGEVRLANEIDRETKDFYNVSVIATDGGG--LKDYSYIEISILDVNDNYPKLKSGS-SMRVNENLPVGSVVGYISVIDLDLGDNSKVEWTYDFLGNSSSMLQIENCTVYTSTVLDRESIEHLHILITMVDMGYPRLTSSATITVSVIDENDNIPKVIYPKTGSLVEEREMDHIAVNSPKYTTVLSIKSFDPDLGINGDVLYHILPSNGSQYFIINQTSG 2260
+ ++GEI T +R D +C P + C +I V V+P + +K+ I+++D NDNAP F ISI EN +P A D D + Y L N F L I + P L V+++ D E +K + +++GG KS+T L V V D+NDN P+F++ + V I EN+ ++++L ATD D G NA+I Y F + P + F L S +G I + + LD E + ++VLA D GS + + +I +NVTD+NDN P I++ + PI E + I + VSD D+ I+ V C EK L+ V + Y + + + DYE K + I+ DSGK L+ + ++D NDN P F + ++ E+ ++ T + A D+DS ++ Y +G + +F +D +G + + DRE +D + +V A D G L+ + + +++LD NDN PK V+ENLP S VG I+V D D G+N+ + + N + +L + + ++ DRE + +D G P +S+A +T++VID NDN P VIYP + + + ++S + V + + D D G+N ++ Y I+ N F I+ +G
Sbjct: 79 LGNTGEIFTTS--NRIDREKLC-PGSSFEDAECS--FEIEVVVLPNDYFRLIKIKIIVKDTNDNAPMFPSPVINISIPENTLINSRFAIPSATDPDTGPNSVHKYELI-NGQSAFGLDIVETPEGEKWPQLIVQQNLDRE---QKDTYVMKIKVEDGGSPQKSSTAILQVTVTDVNDNKPVFRENQIEVHIPENSPIGTSVVQLQATDADIGPNAEIHYVFGTQVSPATKRLFALNSTSGLITVQRPLDREETAIHK--LSVLASD-GSSSPARATVI-INVTDVNDNPPNIDLRYIISPINGTVFLSEKDPINTKIALITVSDKDTDINGKVICFIEK-DVPFHLKAVYDNQYLLETSALLDYEGTKEYNFKIVASDSGKPSLNQTALVRVRLEDENDNPPIFTQPVIELAVMENNKRDLFLTTLSATDEDSGKNAEIVYQLG-PNASFFDLDRKTGVLTASRVFDREDQDRFLFTVTARDNGTPPLQAQAAVIVTVLDENDNNPKFTHNHFQFFVSENLPKYSTVGVITVTDSDAGENAAISLSI-LNDNENFILDPFSGVIKSNVSFDREQQSSYTFDVRAIDSGRPPCSSAAKVTINVIDVNDNTPIVIYPPSNT-----SFKLVPLSSIPGSVVAEVFAVDSDTGMNAELKYTIVSGNNKGLFRIDPVTG 732 HSP 2 Score: 144.436 bits (363), Expect = 1.399e-34 Identity = 162/544 (29.78%), Postives = 242/544 (44.49%), Query Frame = 2
Query: 764 LQLIVNVIDINDNPPIFQKKIVNVTIQENTTFPDAILKLNATDLDSGNNAQISYKFSSINRPIIRETFQL---QSETGKIYLLKTLDYELYSEQNFDINVLAI---DHGSPQLSDSCIIKVNVTDINDNSPV-----IEIVHSQPIPENEQITDPALKLYVSDYDSIDND-----VKCQAEKIGRRLKLEQVEKSSYFIYATEIYDYEKEKNLSLSILCQDSGKEPRYTKQLLTIFIKDVNDNRPKFLRSFYRKSINED---QEKLKPFTKVQAL---DKDSDDFGKVKYSI---------GLKDRKYFSIDEISGEVRLANEIDRETKDFYNVSVIATDGG--GLKDYSYIEISILDVNDNYPKLKSGS-SMRVNENLPVGSVVGYISVIDLDLGDNSKVEWTYDFLGNSSSMLQIENCT--VYTSTVLDRESIEHLHILITMVDMGYPRLTSSATITVSVIDENDNIPKVIYPKTGSLVEEREMDHIAVNSPKYTTVLSIKSFDPDLGINGDVLYHILPSNGSQYFIINQTSGVLKTTWIYD 2287
+++ + V D NDN P+F ++N++I ENT +ATD D+G N+ +K+ IN + F L ++ G+ + + L EQ D V+ I D GSPQ S + I++V VTD+NDN PV IE VH IPEN I ++L +D D N Q +RL + +S I D E+ LS+L D P + + I + DVNDN P + IN EK TK+ + DKD+D GKV I + D +Y + + +D E YN ++A+D G L + + + + D NDN P + V EN + +S D D G N+++ + LG ++S ++ T + S V DRE + +T D G P L + A + V+V+DENDN PK + V E N PKY+TV I D D G N + IL N ++ FI++ SGV+K+ +D
Sbjct: 125 IKIKIIVKDTNDNAPMFPSPVINISIPENTLINSRFAIPSATDPDTGPNS--VHKYELING---QSAFGLDIVETPEGEKWPQLIVQQNLDREQK-DTYVMKIKVEDGGSPQKSSTAILQVTVTDVNDNKPVFRENQIE-VH---IPENSPIGTSVVQLQATDADIGPNAEIHYVFGTQVSPATKRLF--ALNSTSGLITVQRPLDREETAIHKLSVLASDGSSSP--ARATVIINVTDVNDNPPNIDLRYIISPINGTVFLSEKDPINTKIALITVSDKDTDINGKVICFIEKDVPFHLKAVYDNQYL--------LETSALLDYEGTKEYNFKIVASDSGKPSLNQTALVRVRLEDENDNPPIFTQPVIELAVMENNKRDLFLTTLSATDEDSGKNAEIVYQ---LGPNASFFDLDRKTGVLTASRVFDREDQDRFLFTVTARDNGTPPLQAQAAVIVTVLDENDNNPKFTHNHFQFFVSE--------NLPKYSTVGVITVTDSDAGENAAISLSIL--NDNENFILDPFSGVIKSNVSFD 633
BLAST of Protocadherin alpha-2 vs. Ensembl Medaka
Match: pcdh9 (protocadherin 9 [Source:NCBI gene;Acc:101156238]) HSP 1 Score: 227.639 bits (579), Expect = 1.373e-60 Identity = 203/674 (30.12%), Postives = 329/674 (48.81%), Query Frame = 2
Query: 293 ISDSGEIRITKVFDRDDVNNVCGPLGCCDKPSCEIVLDIIVTVIPKNERIPVKVVIVIEDENDNAPDXXXXXXXXXXXXNDATQLDHNLPKALDKDCPIYGIKNYSLSGNKVEYFSLKIRQFQ-----PFLSVKKSFDFENPSEKQFNLSLNAIDNGG--KSATLQLIVNVIDINDNPPIFQKKIVNVTIQENTTFPDAILKLNATDLDSGNNAQISYKFSSINRPIIRETFQLQSETGKIYLLKTLDYELYSEQNFDINVLAIDHGSPQLSDSCIIKVNVTDINDNSPVIEIVH-SQPI------PENEQITDPALKLYVSDYDS-IDNDVKCQAEKIGRRLKLEQVEKSSYFIYATEIYDYEKEKNLSLSILCQDSGKEPRYTKQLLTIFIKDVNDNRPKFLRSFYRKSINEDQEKLKPFTKVQALDKDSDDFGKVKYSIGLKDRKYFSIDEISGEVRLANEIDRETKDFYNVSVIATDGGG--LKDYSYIEISILDVNDNYPKLKSGS-SMRVNENLPVGSVVGYISVIDLDLGDNSKVEWTYDFLGNSSSMLQIENCTVYTSTVLDRESIEHLHILITMVDMGYPRLTSSATITVSVIDENDNIPKVIYPKTGSLVEEREMDHIAVNSPKYTTVLSIKSFDPDLGINGDVLYHILPSNGSQYFIINQTSG 2260
+ ++GEI T +R D +C P + C +I V V+P + +K+ I+++D NDNAP F ISI EN +P A D D + Y L N F L I + P L V+++ D E + + + + D G KS+T L V V D+NDN P+F++ + V I EN+ ++++L ATD D G NA+I Y F + P + F L S +G I + + LD E + ++VLA D GS + + +I +NVTD+NDN P I++ + PI E + I + VSD D+ I+ V C EK L+ V + Y + + + DYE K + I+ DSGK L+ + ++D NDN P F + ++ E+ ++ T + A D+DS ++ Y +G + +F +D +G + + DRE +D + +V A D G L+ + + +++LD NDN PK V+ENLP S VG I+V D D G+N+ + + N + +L + + ++ DRE + +D G P +S+A +T++VID NDN P VIYP + + + ++S + V + + D D G+N ++ Y I+ N F I+ +G
Sbjct: 79 LGNTGEIFTTS--NRIDREKLC-PGSSFEDAECS--FEIEVVVLPNDYFRLIKIKIIVKDTNDNAPMFPSPVINISIPENTLINSRFAIPSATDPDTGPNSVHKYELI-NGQSAFGLDIVETPEGEKWPQLIVQQNLDREQ--KDTYVMKIKVEDGGSPQKSSTAILQVTVTDVNDNKPVFRENQIEVHIPENSPIGTSVVQLQATDADIGPNAEIHYVFGTQVSPATKRLFALNSTSGLITVQRPLDREETAIHK--LSVLASD-GSSSPARATVI-INVTDVNDNPPNIDLRYIISPINGTVFLSEKDPINTKIALITVSDKDTDINGKVICFIEK-DVPFHLKAVYDNQYLLETSALLDYEGTKEYNFKIVASDSGKPSLNQTALVRVRLEDENDNPPIFTQPVIELAVMENNKRDLFLTTLSATDEDSGKNAEIVYQLG-PNASFFDLDRKTGVLTASRVFDREDQDRFLFTVTARDNGTPPLQAQAAVIVTVLDENDNNPKFTHNHFQFFVSENLPKYSTVGVITVTDSDAGENAAISLSI-LNDNENFILDPFSGVIKSNVSFDREQQSSYTFDVRAIDSGRPPCSSAAKVTINVIDVNDNTPIVIYPPSNT-----SFKLVPLSSIPGSVVAEVFAVDSDTGMNAELKYTIVSGNNKGLFRIDPVTG 732 HSP 2 Score: 145.206 bits (365), Expect = 1.154e-34 Identity = 160/543 (29.47%), Postives = 240/543 (44.20%), Query Frame = 2
Query: 764 LQLIVNVIDINDNPPIFQKKIVNVTIQENTTFPDAILKLNATDLDSGNNAQISYKFSSINRPIIRETFQL---QSETGKIYLLKTLDYELYSEQNFDINVLAI---DHGSPQLSDSCIIKVNVTDINDNSPVIEI----VHSQPIPENEQITDPALKLYVSDYDSIDND-----VKCQAEKIGRRLKLEQVEKSSYFIYATEIYDYEKEKNLSLSILCQDSGKEPRYTKQLLTIFIKDVNDNRPKFLRSFYRKSINED---QEKLKPFTKVQAL---DKDSDDFGKVKYSI---------GLKDRKYFSIDEISGEVRLANEIDRETKDFYNVSVIATDGG--GLKDYSYIEISILDVNDNYPKLKSGS-SMRVNENLPVGSVVGYISVIDLDLGDNSKVEWTYDFLGNSSSMLQIENCT--VYTSTVLDRESIEHLHILITMVDMGYPRLTSSATITVSVIDENDNIPKVIYPKTGSLVEEREMDHIAVNSPKYTTVLSIKSFDPDLGINGDVLYHILPSNGSQYFIINQTSGVLKTTWIYD 2287
+++ + V D NDN P+F ++N++I ENT +ATD D+G N+ +K+ IN + F L ++ G+ + + L EQ D V+ I D GSPQ S + I++V VTD+NDN PV VH IPEN I ++L +D D N Q +RL + +S I D E+ LS+L D P + + I + DVNDN P + IN EK TK+ + DKD+D GKV I + D +Y + + +D E YN ++A+D G L + + + + D NDN P + V EN + +S D D G N+++ + LG ++S ++ T + S V DRE + +T D G P L + A + V+V+DENDN PK + V E N PKY+TV I D D G N + IL N ++ FI++ SGV+K+ +D
Sbjct: 125 IKIKIIVKDTNDNAPMFPSPVINISIPENTLINSRFAIPSATDPDTGPNS--VHKYELING---QSAFGLDIVETPEGEKWPQLIVQQNLDREQK-DTYVMKIKVEDGGSPQKSSTAILQVTVTDVNDNKPVFRENQIEVH---IPENSPIGTSVVQLQATDADIGPNAEIHYVFGTQVSPATKRLF--ALNSTSGLITVQRPLDREETAIHKLSVLASDGSSSP--ARATVIINVTDVNDNPPNIDLRYIISPINGTVFLSEKDPINTKIALITVSDKDTDINGKVICFIEKDVPFHLKAVYDNQYL--------LETSALLDYEGTKEYNFKIVASDSGKPSLNQTALVRVRLEDENDNPPIFTQPVIELAVMENNKRDLFLTTLSATDEDSGKNAEIVYQ---LGPNASFFDLDRKTGVLTASRVFDREDQDRFLFTVTARDNGTPPLQAQAAVIVTVLDENDNNPKFTHNHFQFFVSE--------NLPKYSTVGVITVTDSDAGENAAISLSIL--NDNENFILDPFSGVIKSNVSFD 633
BLAST of Protocadherin alpha-2 vs. Ensembl Medaka
Match: pcdh9 (protocadherin 9 [Source:NCBI gene;Acc:101156238]) HSP 1 Score: 227.254 bits (578), Expect = 2.486e-60 Identity = 203/674 (30.12%), Postives = 329/674 (48.81%), Query Frame = 2
Query: 293 ISDSGEIRITKVFDRDDVNNVCGPLGCCDKPSCEIVLDIIVTVIPKNERIPVKVVIVIEDENDNAPDXXXXXXXXXXXXNDATQLDHNLPKALDKDCPIYGIKNYSLSGNKVEYFSLKIRQFQ-----PFLSVKKSFDFENPSEKQFNLSLNAIDNGG--KSATLQLIVNVIDINDNPPIFQKKIVNVTIQENTTFPDAILKLNATDLDSGNNAQISYKFSSINRPIIRETFQLQSETGKIYLLKTLDYELYSEQNFDINVLAIDHGSPQLSDSCIIKVNVTDINDNSPVIEIVH-SQPI------PENEQITDPALKLYVSDYDS-IDNDVKCQAEKIGRRLKLEQVEKSSYFIYATEIYDYEKEKNLSLSILCQDSGKEPRYTKQLLTIFIKDVNDNRPKFLRSFYRKSINEDQEKLKPFTKVQALDKDSDDFGKVKYSIGLKDRKYFSIDEISGEVRLANEIDRETKDFYNVSVIATDGGG--LKDYSYIEISILDVNDNYPKLKSGS-SMRVNENLPVGSVVGYISVIDLDLGDNSKVEWTYDFLGNSSSMLQIENCTVYTSTVLDRESIEHLHILITMVDMGYPRLTSSATITVSVIDENDNIPKVIYPKTGSLVEEREMDHIAVNSPKYTTVLSIKSFDPDLGINGDVLYHILPSNGSQYFIINQTSG 2260
+ ++GEI T +R D +C P + C +I V V+P + +K+ I+++D NDNAP F ISI EN +P A D D + Y L N F L I + P L V+++ D E + + + + D G KS+T L V V D+NDN P+F++ + V I EN+ ++++L ATD D G NA+I Y F + P + F L S +G I + + LD E + ++VLA D GS + + +I +NVTD+NDN P I++ + PI E + I + VSD D+ I+ V C EK L+ V + Y + + + DYE K + I+ DSGK L+ + ++D NDN P F + ++ E+ ++ T + A D+DS ++ Y +G + +F +D +G + + DRE +D + +V A D G L+ + + +++LD NDN PK V+ENLP S VG I+V D D G+N+ + + N + +L + + ++ DRE + +D G P +S+A +T++VID NDN P VIYP + + + ++S + V + + D D G+N ++ Y I+ N F I+ +G
Sbjct: 79 LGNTGEIFTTS--NRIDREKLC-PGSSFEDAECS--FEIEVVVLPNDYFRLIKIKIIVKDTNDNAPMFPSPVINISIPENTLINSRFAIPSATDPDTGPNSVHKYELI-NGQSAFGLDIVETPEGEKWPQLIVQQNLDREQ--KDTYVMKIKVEDGGSPQKSSTAILQVTVTDVNDNKPVFRENQIEVHIPENSPIGTSVVQLQATDADIGPNAEIHYVFGTQVSPATKRLFALNSTSGLITVQRPLDREETAIHK--LSVLASD-GSSSPARATVI-INVTDVNDNPPNIDLRYIISPINGTVFLSEKDPINTKIALITVSDKDTDINGKVICFIEK-DVPFHLKAVYDNQYLLETSALLDYEGTKEYNFKIVASDSGKPSLNQTALVRVRLEDENDNPPIFTQPVIELAVMENNKRDLFLTTLSATDEDSGKNAEIVYQLG-PNASFFDLDRKTGVLTASRVFDREDQDRFLFTVTARDNGTPPLQAQAAVIVTVLDENDNNPKFTHNHFQFFVSENLPKYSTVGVITVTDSDAGENAAISLSI-LNDNENFILDPFSGVIKSNVSFDREQQSSYTFDVRAIDSGRPPCSSAAKVTINVIDVNDNTPIVIYPPSNT-----SFKLVPLSSIPGSVVAEVFAVDSDTGMNAELKYTIVSGNNKGLFRIDPVTG 732 HSP 2 Score: 144.436 bits (363), Expect = 1.856e-34 Identity = 160/543 (29.47%), Postives = 240/543 (44.20%), Query Frame = 2
Query: 764 LQLIVNVIDINDNPPIFQKKIVNVTIQENTTFPDAILKLNATDLDSGNNAQISYKFSSINRPIIRETFQL---QSETGKIYLLKTLDYELYSEQNFDINVLAI---DHGSPQLSDSCIIKVNVTDINDNSPVIEI----VHSQPIPENEQITDPALKLYVSDYDSIDND-----VKCQAEKIGRRLKLEQVEKSSYFIYATEIYDYEKEKNLSLSILCQDSGKEPRYTKQLLTIFIKDVNDNRPKFLRSFYRKSINED---QEKLKPFTKVQAL---DKDSDDFGKVKYSI---------GLKDRKYFSIDEISGEVRLANEIDRETKDFYNVSVIATDGG--GLKDYSYIEISILDVNDNYPKLKSGS-SMRVNENLPVGSVVGYISVIDLDLGDNSKVEWTYDFLGNSSSMLQIENCT--VYTSTVLDRESIEHLHILITMVDMGYPRLTSSATITVSVIDENDNIPKVIYPKTGSLVEEREMDHIAVNSPKYTTVLSIKSFDPDLGINGDVLYHILPSNGSQYFIINQTSGVLKTTWIYD 2287
+++ + V D NDN P+F ++N++I ENT +ATD D+G N+ +K+ IN + F L ++ G+ + + L EQ D V+ I D GSPQ S + I++V VTD+NDN PV VH IPEN I ++L +D D N Q +RL + +S I D E+ LS+L D P + + I + DVNDN P + IN EK TK+ + DKD+D GKV I + D +Y + + +D E YN ++A+D G L + + + + D NDN P + V EN + +S D D G N+++ + LG ++S ++ T + S V DRE + +T D G P L + A + V+V+DENDN PK + V E N PKY+TV I D D G N + IL N ++ FI++ SGV+K+ +D
Sbjct: 125 IKIKIIVKDTNDNAPMFPSPVINISIPENTLINSRFAIPSATDPDTGPNS--VHKYELING---QSAFGLDIVETPEGEKWPQLIVQQNLDREQK-DTYVMKIKVEDGGSPQKSSTAILQVTVTDVNDNKPVFRENQIEVH---IPENSPIGTSVVQLQATDADIGPNAEIHYVFGTQVSPATKRLF--ALNSTSGLITVQRPLDREETAIHKLSVLASDGSSSP--ARATVIINVTDVNDNPPNIDLRYIISPINGTVFLSEKDPINTKIALITVSDKDTDINGKVICFIEKDVPFHLKAVYDNQYL--------LETSALLDYEGTKEYNFKIVASDSGKPSLNQTALVRVRLEDENDNPPIFTQPVIELAVMENNKRDLFLTTLSATDEDSGKNAEIVYQ---LGPNASFFDLDRKTGVLTASRVFDREDQDRFLFTVTARDNGTPPLQAQAAVIVTVLDENDNNPKFTHNHFQFFVSE--------NLPKYSTVGVITVTDSDAGENAAISLSIL--NDNENFILDPFSGVIKSNVSFD 633
BLAST of Protocadherin alpha-2 vs. Ensembl Medaka
Match: pcdh11 (protocadherin-11 X-linked [Source:NCBI gene;Acc:101161492]) HSP 1 Score: 225.328 bits (573), Expect = 4.221e-60 Identity = 205/680 (30.15%), Postives = 320/680 (47.06%), Query Frame = 2
Query: 254 RRSSFTKFNQYFRISDSGEIRIT----KVF---DRDDVNNVCGPLGCCDKPSCEIVLDIIVTVIPKNERIPVKVVIVIEDENDNAPDXXXXXXXXXXXXNDATQLDHNLPKALDKDCPIYGIKNYSLSGNKVEYFSLKIRQFQ-----PFLSVKKSFDFENPSEKQFNLSLNAIDNGG--KSATLQLIVNVIDINDNPPIFQKKIVNVTIQENTTFPDAILKLNATDLDSGNNAQISYKFSSINRPIIRETFQLQSETGKIYLLKTLDYELYSEQNFDINVLAIDHGSPQLSDSCIIKVNVTDINDNSPVIE-----------IVHSQPIPENEQITDPALKLYVSDYDS-IDNDVKCQAEKIGRRLKLEQVEKSSYFIYATEIYDYEKEKNLSLSILCQDSGKEPRYTKQLLTIFIKDVNDNRPKFLRSFYRKSINEDQEKLKPFTKVQALDKDSDDFGKVKYSIGLKDRKYFSIDEISGEVRLANEIDRETKDFYNVSVIATDGGG--LKDYSYIEISILDVNDNYPKLKSGS-SMRVNENLPVGSVVGYISVIDLDLGDNSKVEWTYDFLGNSSSMLQIENCTVYTSTVLDRESIEHLHILITMVDMGYPRLTSSATITVSVIDENDNIPKVIYPKTGSLVEEREMDHIAVNSPKYTTVLSIKSFDPDLGINGDVLY 2206
R SS +F ++ D +R+ ++F R D +C G + C +I V V+P VK+ +IED NDNAP F + ISI EN A + +P A D D I GI+NY L + E F L I + P L V+++ D E F + + D G KS+T L V + D+NDN PIFQ + V++ EN ++ +L+ATD D G+NAQI + FS+ + F + S TG I + + LD E+ + VLA D GS + I VNVTD+NDN P I+ ++ S+ P N +I AL + V+D D+ + V C + +L+ V + + DYE + ++ I+ D G P T ++ I IKD NDN P F + + SI E+ + K+ A D DS ++ Y++G F ID SG + + +DRE ++ ++ VIA D G L+ + + + D+NDN P + V ENLP+ VG I+V D D GDN+ + + G + ++ + + + DRE ++ +D G P +S A +T++V+D NDN P + P + D + + V + + D D G+N ++ Y
Sbjct: 56 RLSSPLQFKPVYKTGDVPLVRVEANTGEIFTTNHRIDREKLCS--GVFTEKRC--YYEIEVAVLPDEIFRLVKIRFLIEDVNDNAPLFQSTVINISIPENTAINTRYPVPSAFDPDVGINGIQNYELVKSVTE-FGLDIIETPEGDKWPQLIVQQNLDREK--RDTFVMKIKVEDGGNPPKSSTAILQVTISDVNDNRPIFQDSELEVSVPENAPTGTSVAQLHATDADWGSNAQIHFAFSNQISSSTKRHFAINSSTGLITVKQPLDREVTPVHK--LIVLASDGGSTPSRATVI--VNVTDVNDNVPAIDTRYIINLVNGTVLLSENAPLNTKI---AL-ITVTDKDADLYGKVACYTDH-DVPFRLKPVFNDQFLLETAAPLDYETTREYAIKIVASDRGTPPLNTSAMVLIKIKDENDNAPIFPQPEIQLSIPENNDPSTQLIKISATDADSGSNAEIIYTLGPDAPDGFHIDRRSGILSVGKRLDREKQERFSFIVIARDNGSTPLQSNVTVRLIVQDLNDNSPAFTHPEYNFYVPENLPLYGTVGLITVTDADAGDNAAITLSI-LNGKDNFIIDPQTGVIKPNITFDREQQSSYTFMVKAIDGGQPPTSSYAKVTINVVDVNDNRPVFVIPSSN-----YSYDLVRTTTTPGAVVTRVFAIDNDTGMNAELQY 713 HSP 2 Score: 122.865 bits (307), Expect = 7.477e-28 Identity = 139/521 (26.68%), Postives = 223/521 (42.80%), Query Frame = 2
Query: 788 DINDNPPIFQKKIVNVTIQENTTFPDAILKLNATDLDSGNNAQISYKF----SSINRPIIRETFQLQSETGKIYLLKTLDYELYSEQNFDINVLAIDHGSPQLSDSCIIKVNVTDINDNSPVIEIVHSQ-PIPENEQITDPALKLYVSDYDSIDNDVKCQA--EKIGRRLKLE-QVEKSSYFIYATEIYDYEKEKNLSLSILCQDSGKEPRYTKQLLTIFIKDVNDNRPKFLRSFYRKSIN------EDQEKLKPFTKVQALDKDSDDFGKVK----YSIGLKDRKYFSIDEISGEVRLANEIDRETKDFYNVSVIATDGGG--LKDYSYIEISILDVNDNYPKLKSGS-SMRVNENLPVGSVVGYISVIDLDLGDNSKVEWTYDFLGNSSSMLQIENCTVYTSTVLDRESIEHLHILITMVDMGYPRLTSSATITVSVIDENDNIPKVIYPKTGSLVEEREMDHIAVNSPKYTTVLSIKSFDPDLGINGDVLYHILPSNGSQYFIINQTSGVLKTTWIYD 2287
D+NDN P+FQ ++N++I ENT +A D D G N +Y+ + II ET + + ++ + + LD E F + + D G+P S + I++V ++D+NDN P+ + + +PEN +L+ +D D N A +I K + S+ I + D E L +L D G P ++ + + + DVNDN P + +N E+ + DKD+D +GKV + + + + F+ D+ E A +D ET Y + ++A+D G L + + I I D NDN P + + EN + + IS D D G N+++ +T + + + LDRE E ++ D G L S+ T+ + V D NDN P +P+ V E N P Y TV I D D G N + IL NG FII+ +GV+K +D
Sbjct: 131 DVNDNAPLFQSTVINISIPENTAINTRYPVPSAFDPDVGINGIQNYELVKSVTEFGLDII-ETPE-GDKWPQLIVQQNLDRE--KRDTFVMKIKVEDGGNPPKSSTAILQVTISDVNDNRPIFQDSELEVSVPENAPTGTSVAQLHATDADWGSNAQIHFAFSNQISSSTKRHFAINSSTGLITVKQPLDREVTPVHKLIVLASDGGSTP--SRATVIVNVTDVNDNVPAIDTRYIINLVNGTVLLSENAPLNTKIALITVTDKDADLYGKVACYTDHDVPFRLKPVFN-DQFLLET--AAPLDYETTREYAIKIVASDRGTPPLNTSAMVLIKIKDENDNAPIFPQPEIQLSIPENNDPSTQLIKISATDADSGSNAEIIYTLGPDAPDGFHIDRRSGILSVGKRLDREKQERFSFIVIARDNGSTPLQSNVTVRLIVQDLNDNSPAFTHPEYNFYVPE--------NLPLYGTVGLITVTDADAGDNAAITLSIL--NGKDNFIIDPQTGVIKPNITFD 632
BLAST of Protocadherin alpha-2 vs. Ensembl Medaka
Match: pcdh11 (protocadherin-11 X-linked [Source:NCBI gene;Acc:101161492]) HSP 1 Score: 225.328 bits (573), Expect = 5.547e-60 Identity = 204/684 (29.82%), Postives = 315/684 (46.05%), Query Frame = 2
Query: 254 RRSSFTKFNQYFRISDSGEIRIT----KVF---DRDDVNNVCGPLGCCDKPSCEIVLDIIVTVIPKNERIPVKVVIVIEDENDNAPDXXXXXXXXXXXXNDATQLDHNLPKALDKDCPIYGIKNYSLSGNKVEYFSLKIRQFQ-----PFLSVKKSFDFENPSEKQFNLSLNAIDNGG--KSATLQLIVNVIDINDNPPIFQKKIVNVTIQENTTFPDAILKLNATDLDSGNNAQISYKFSSINRPIIRETFQLQSETGKIYLLKTLDYELYSEQNFDINVLAIDHGSPQLSDSCIIKVNVTDINDNSPVIE-----------IVHSQPIPENEQI-----TDPALKLYVSDYDSIDNDVKCQAEKIGRRLKLEQVEKSSYFIYATEIYDYEKEKNLSLSILCQDSGKEPRYTKQLLTIFIKDVNDNRPKFLRSFYRKSINEDQEKLKPFTKVQALDKDSDDFGKVKYSIGLKDRKYFSIDEISGEVRLANEIDRETKDFYNVSVIATDGGG--LKDYSYIEISILDVNDNYPKLKSGS-SMRVNENLPVGSVVGYISVIDLDLGDNSKVEWTYDFLGNSSSMLQIENCTVYTSTVLDRESIEHLHILITMVDMGYPRLTSSATITVSVIDENDNIPKVIYPKTGSLVEEREMDHIAVNSPKYTTVLSIKSFDPDLGINGDVLY 2206
R SS +F ++ D +R+ ++F R D +C G + C +I V V+P VK+ +IED NDNAP F + ISI EN A + +P A D D I GI+NY L + E F L I + P L V+++ D E F + + D G KS+T L V + D+NDN PIFQ + V++ EN ++ +L+ATD D G+NAQI + FS+ + F + S TG I + + LD E+ + VLA D GS + VNVTD+NDN P I+ ++ S+ P N +I TD LY D+DV +L+ V + + DYE + ++ I+ D G P T ++ I IKD NDN P F + + SI E+ + K+ A D DS ++ Y++G F ID SG + + +DRE ++ ++ VIA D G L+ + + + D+NDN P + V ENLP+ VG I+V D D GDN+ + + G + ++ + + + DRE ++ +D G P +S A +T++V+D NDN P + P + D + + V + + D D G+N ++ Y
Sbjct: 56 RLSSPLQFKPVYKTGDVPLVRVEANTGEIFTTNHRIDREKLCS--GVFTEKRC--YYEIEVAVLPDEIFRLVKIRFLIEDVNDNAPLFQSTVINISIPENTAINTRYPVPSAFDPDVGINGIQNYELVKSVTE-FGLDIIETPEGDKWPQLIVQQNLDREK--RDTFVMKIKVEDGGNPPKSSTAILQVTISDVNDNRPIFQDSELEVSVPENAPTGTSVAQLHATDADWGSNAQIHFAFSNQISSSTKRHFAINSSTGLITVKQPLDREVTPVHK--LIVLASDGGS--TPSRATVIVNVTDVNDNVPAIDTRYIINLVNGTVLLSENAPLNTKIALITVTDKDADLYGKVACYTDHDVP---------FRLKPVFNDQFLLETAAPLDYETTREYAIKIVASDRGTPPLNTSAMVLIKIKDENDNAPIFPQPEIQLSIPENNDPSTQLIKISATDADSGSNAEIIYTLGPDAPDGFHIDRRSGILSVGKRLDREKQERFSFIVIARDNGSTPLQSNVTVRLIVQDLNDNSPAFTHPEYNFYVPENLPLYGTVGLITVTDADAGDNAAITLSI-LNGKDNFIIDPQTGVIKPNITFDREQQSSYTFMVKAIDGGQPPTSSYAKVTINVVDVNDNRPVFVIPSSN-----YSYDLVRTTTTPGAVVTRVFAIDNDTGMNAELQY 713 HSP 2 Score: 122.865 bits (307), Expect = 6.695e-28 Identity = 139/521 (26.68%), Postives = 223/521 (42.80%), Query Frame = 2
Query: 788 DINDNPPIFQKKIVNVTIQENTTFPDAILKLNATDLDSGNNAQISYKF----SSINRPIIRETFQLQSETGKIYLLKTLDYELYSEQNFDINVLAIDHGSPQLSDSCIIKVNVTDINDNSPVIEIVHSQ-PIPENEQITDPALKLYVSDYDSIDNDVKCQA--EKIGRRLKLE-QVEKSSYFIYATEIYDYEKEKNLSLSILCQDSGKEPRYTKQLLTIFIKDVNDNRPKFLRSFYRKSIN------EDQEKLKPFTKVQALDKDSDDFGKVK----YSIGLKDRKYFSIDEISGEVRLANEIDRETKDFYNVSVIATDGGG--LKDYSYIEISILDVNDNYPKLKSGS-SMRVNENLPVGSVVGYISVIDLDLGDNSKVEWTYDFLGNSSSMLQIENCTVYTSTVLDRESIEHLHILITMVDMGYPRLTSSATITVSVIDENDNIPKVIYPKTGSLVEEREMDHIAVNSPKYTTVLSIKSFDPDLGINGDVLYHILPSNGSQYFIINQTSGVLKTTWIYD 2287
D+NDN P+FQ ++N++I ENT +A D D G N +Y+ + II ET + + ++ + + LD E F + + D G+P S + I++V ++D+NDN P+ + + +PEN +L+ +D D N A +I K + S+ I + D E L +L D G P ++ + + + DVNDN P + +N E+ + DKD+D +GKV + + + + F+ D+ E A +D ET Y + ++A+D G L + + I I D NDN P + + EN + + IS D D G N+++ +T + + + LDRE E ++ D G L S+ T+ + V D NDN P +P+ V E N P Y TV I D D G N + IL NG FII+ +GV+K +D
Sbjct: 131 DVNDNAPLFQSTVINISIPENTAINTRYPVPSAFDPDVGINGIQNYELVKSVTEFGLDII-ETPE-GDKWPQLIVQQNLDRE--KRDTFVMKIKVEDGGNPPKSSTAILQVTISDVNDNRPIFQDSELEVSVPENAPTGTSVAQLHATDADWGSNAQIHFAFSNQISSSTKRHFAINSSTGLITVKQPLDREVTPVHKLIVLASDGGSTP--SRATVIVNVTDVNDNVPAIDTRYIINLVNGTVLLSENAPLNTKIALITVTDKDADLYGKVACYTDHDVPFRLKPVFN-DQFLLET--AAPLDYETTREYAIKIVASDRGTPPLNTSAMVLIKIKDENDNAPIFPQPEIQLSIPENNDPSTQLIKISATDADSGSNAEIIYTLGPDAPDGFHIDRRSGILSVGKRLDREKQERFSFIVIARDNGSTPLQSNVTVRLIVQDLNDNSPAFTHPEYNFYVPE--------NLPLYGTVGLITVTDADAGDNAAITLSIL--NGKDNFIIDPQTGVIKPNITFD 632
BLAST of Protocadherin alpha-2 vs. Planmine SMEST
Match: SMESG000069340.1 (SMESG000069340.1) HSP 1 Score: 1996.86 bits (5172), Expect = 0.000e+0 Identity = 1032/1049 (98.38%), Postives = 1032/1049 (98.38%), Query Frame = 2
Query: 65 MPTTMQILPSMLIVSFVLISVISADIFTARFTIPDNNARHSSVGNIISKLPSRFPRGSYQIITRRSSFTKFNQYFRISDSGEIRITKVFDRDDVNNVCGPLGCCDKPSCEIVLDIIVTVIPKNERIPVKVVIVIEDENDNAPDXXXXXXXXXXXXNDATQLDHNLPKALDKDCPIYGIKNYSLSGNKVEYFSLKIRQFQPFLSVKKSFDFENPSEKQFNLSLNAIDNGGKSATLQLIVNVIDINDNPPIFQKKIVNVTIQENTTFPDAILKLNATDLDSGNNAQISYKFSSINRPIIRETFQLQSETGKIYLLKTLDYELYSEQNFDINVLAIDHGSPQLSDSCIIKVNVTDINDNSPVIEIVHSQPIPENEQITDPALKLYVSDYDSIDNDVKCQAEKIGRRLKLEQVEKSSYFIYATEIYDYEKEKNLSLSILCQDSGKEPRYTKQLLTIFIKDVNDNRPKFLRSFYRKSINEDQEKLKPFTKVQALDKDSDDFGKVKYSIGLKDRKYFSIDEISGEVRLANEIDRETKDFYNVSVIATDGGGLKDYSYIEISILDVNDNYPKLKSGSSMRVNENLPVGSVVGYISVIDLDLGDNSKVEWTYDFLGNSSSMLQIENCTVYTSTVLDRESIEHLHILITMVDMGYPRLTSSATITVSVIDENDNIPKVIYPKTGSLVEEREMDHIAVNSPKYTTVLSIKSFDPDLGINGDVLYHILPSNGSQYFIINQTSGVLKTTWIYDTISFTPLHPKEDIYKISYAAYNQVXXXXXXXXXXXXFFYVRIGPYKHFVNNEVFYKYHKRPFFNNIVLLILIGGFTXXXXXXXXXXXVWAKSKYSTESTSLEQAQANDGKFMMMMMSGELRNTNNTYVYDPYASLIVDADRTIDSGYALSHSRSSTFNSRNNVREHGLINGYDAKTMPRSLIQSNMMHQYPSDPDNQGNXXXXXXXXXXXXXXXKHHKPVNKMKSMNSNERDVAGNLKTFYRHFEHDQQCVSPMINKVNRHRSFDQQYGSISPRIASICDPTPAAVSSSHWVPKDLTADNGSNSFTIC 3211
MPTTMQILPSMLIVSFVLISVISADIFTARFTIPDNNARHSSVGNIISKLPSRFPRGSYQIITRRSSFTKFNQYFRISDSGEIRITKVFDRDDVNNVCGPLGCCDKPSCEIVLDIIVTVIPKNERIPVKVVIVIEDENDNAPDFSESSFTISIFENDATQLDHNLPKALDKDCPIYGIKNYSLSGNKVEYFSLKIRQFQPFLSVKKSFDFENPSEKQFNLSLNAIDNGGKSATLQLIVNVIDINDNPPIFQKKIVNVTIQENTTFPDAILKLNATDLDSGNNAQISYKFSSINRPIIRETFQLQSETGKIYLLKTLDYELYSEQNFDINVLAIDHGSPQLSDSCIIKVNVTDINDNSPVIEIVHSQPIPENEQITDPALKLYVSDYDSIDNDVKCQAEKIGRRLKLEQVEKSSYFIYATEIYDYEKEKNLSLSILCQDSGKEPRYTKQLLTIFIKDVNDNRPKFLRSFYRKSINEDQEKLKPFTKVQALDKDSDDFGKVKYSIGLKDRKYFSIDEISGEVRLANEIDRETKDFYNVSVIATDGGGLKDYSYIEISILDVNDNYPKLKSGSSMRVNENLPVGSVVGYISVIDLDLGDNSKVEWTYDFLGNSSSMLQIENCTVYTSTVLDRESIEHLHILITMVDMGYPRLTSSATITVSVIDENDNIPKVIYPKTGSLVEEREMDHIAVNSPKYTTVLSIKSFDPDLGINGDVLYHILPSNGSQYFIINQTSGVLKTTWIYDTISFTPLHPKEDIYKISYAAYNQVKSSKNLSSSINSFFYVRIGPYKHFVNNEVFYKYHKRPFFNNIVLLILIGGFTISLSAALIAAIVWAKSKYSTESTSLEQAQANDGKFMMMMMSGELRNTNNTYVYDPYASLIVDADRTIDSGYALSHSRSSTFNSRNNVREHGLINGYDAKTMPRSLIQSNMMHQYPSDPDNQGNSLSTTDLVSSTSATVKHHKPVN TFYRHFEHDQQCVSPMINKVNRHRSFDQQYGSISPRIASICDPTPAAVSSSHWVPKDLTADNGSNSFTIC
Sbjct: 1 MPTTMQILPSMLIVSFVLISVISADIFTARFTIPDNNARHSSVGNIISKLPSRFPRGSYQIITRRSSFTKFNQYFRISDSGEIRITKVFDRDDVNNVCGPLGCCDKPSCEIVLDIIVTVIPKNERIPVKVVIVIEDENDNAPDFSESSFTISIFENDATQLDHNLPKALDKDCPIYGIKNYSLSGNKVEYFSLKIRQFQPFLSVKKSFDFENPSEKQFNLSLNAIDNGGKSATLQLIVNVIDINDNPPIFQKKIVNVTIQENTTFPDAILKLNATDLDSGNNAQISYKFSSINRPIIRETFQLQSETGKIYLLKTLDYELYSEQNFDINVLAIDHGSPQLSDSCIIKVNVTDINDNSPVIEIVHSQPIPENEQITDPALKLYVSDYDSIDNDVKCQAEKIGRRLKLEQVEKSSYFIYATEIYDYEKEKNLSLSILCQDSGKEPRYTKQLLTIFIKDVNDNRPKFLRSFYRKSINEDQEKLKPFTKVQALDKDSDDFGKVKYSIGLKDRKYFSIDEISGEVRLANEIDRETKDFYNVSVIATDGGGLKDYSYIEISILDVNDNYPKLKSGSSMRVNENLPVGSVVGYISVIDLDLGDNSKVEWTYDFLGNSSSMLQIENCTVYTSTVLDRESIEHLHILITMVDMGYPRLTSSATITVSVIDENDNIPKVIYPKTGSLVEEREMDHIAVNSPKYTTVLSIKSFDPDLGINGDVLYHILPSNGSQYFIINQTSGVLKTTWIYDTISFTPLHPKEDIYKISYAAYNQVKSSKNLSSSINSFFYVRIGPYKHFVNNEVFYKYHKRPFFNNIVLLILIGGFTISLSAALIAAIVWAKSKYSTESTSLEQAQANDGKFMMMMMSGELRNTNNTYVYDPYASLIVDADRTIDSGYALSHSRSSTFNSRNNVREHGLINGYDAKTMPRSLIQSNMMHQYPSDPDNQGNSLSTTDLVSSTSATVKHHKPVN-----------------TFYRHFEHDQQCVSPMINKVNRHRSFDQQYGSISPRIASICDPTPAAVSSSHWVPKDLTADNGSNSFTIC 1032
BLAST of Protocadherin alpha-2 vs. Planmine SMEST
Match: SMESG000069340.1 (SMESG000069340.1) HSP 1 Score: 1890.55 bits (4896), Expect = 0.000e+0 Identity = 979/979 (100.00%), Postives = 979/979 (100.00%), Query Frame = 2
Query: 65 MPTTMQILPSMLIVSFVLISVISADIFTARFTIPDNNARHSSVGNIISKLPSRFPRGSYQIITRRSSFTKFNQYFRISDSGEIRITKVFDRDDVNNVCGPLGCCDKPSCEIVLDIIVTVIPKNERIPVKVVIVIEDENDNAPDXXXXXXXXXXXXNDATQLDHNLPKALDKDCPIYGIKNYSLSGNKVEYFSLKIRQFQPFLSVKKSFDFENPSEKQFNLSLNAIDNGGKSATLQLIVNVIDINDNPPIFQKKIVNVTIQENTTFPDAILKLNATDLDSGNNAQISYKFSSINRPIIRETFQLQSETGKIYLLKTLDYELYSEQNFDINVLAIDHGSPQLSDSCIIKVNVTDINDNSPVIEIVHSQPIPENEQITDPALKLYVSDYDSIDNDVKCQAEKIGRRLKLEQVEKSSYFIYATEIYDYEKEKNLSLSILCQDSGKEPRYTKQLLTIFIKDVNDNRPKFLRSFYRKSINEDQEKLKPFTKVQALDKDSDDFGKVKYSIGLKDRKYFSIDEISGEVRLANEIDRETKDFYNVSVIATDGGGLKDYSYIEISILDVNDNYPKLKSGSSMRVNENLPVGSVVGYISVIDLDLGDNSKVEWTYDFLGNSSSMLQIENCTVYTSTVLDRESIEHLHILITMVDMGYPRLTSSATITVSVIDENDNIPKVIYPKTGSLVEEREMDHIAVNSPKYTTVLSIKSFDPDLGINGDVLYHILPSNGSQYFIINQTSGVLKTTWIYDTISFTPLHPKEDIYKISYAAYNQVXXXXXXXXXXXXFFYVRIGPYKHFVNNEVFYKYHKRPFFNNIVLLILIGGFTXXXXXXXXXXXVWAKSKYSTESTSLEQAQANDGKFMMMMMSGELRNTNNTYVYDPYASLIVDADRTIDSGYALSHSRSSTFNSRNNVREHGLINGYDAKTMPRSLIQSNMMHQYPSDPDNQGNXXXXXXXXXXXXXXXKHHKPVNKMKSMNSNERDVAGNLK 3001
MPTTMQILPSMLIVSFVLISVISADIFTARFTIPDNNARHSSVGNIISKLPSRFPRGSYQIITRRSSFTKFNQYFRISDSGEIRITKVFDRDDVNNVCGPLGCCDKPSCEIVLDIIVTVIPKNERIPVKVVIVIEDENDNAPDFSESSFTISIFENDATQLDHNLPKALDKDCPIYGIKNYSLSGNKVEYFSLKIRQFQPFLSVKKSFDFENPSEKQFNLSLNAIDNGGKSATLQLIVNVIDINDNPPIFQKKIVNVTIQENTTFPDAILKLNATDLDSGNNAQISYKFSSINRPIIRETFQLQSETGKIYLLKTLDYELYSEQNFDINVLAIDHGSPQLSDSCIIKVNVTDINDNSPVIEIVHSQPIPENEQITDPALKLYVSDYDSIDNDVKCQAEKIGRRLKLEQVEKSSYFIYATEIYDYEKEKNLSLSILCQDSGKEPRYTKQLLTIFIKDVNDNRPKFLRSFYRKSINEDQEKLKPFTKVQALDKDSDDFGKVKYSIGLKDRKYFSIDEISGEVRLANEIDRETKDFYNVSVIATDGGGLKDYSYIEISILDVNDNYPKLKSGSSMRVNENLPVGSVVGYISVIDLDLGDNSKVEWTYDFLGNSSSMLQIENCTVYTSTVLDRESIEHLHILITMVDMGYPRLTSSATITVSVIDENDNIPKVIYPKTGSLVEEREMDHIAVNSPKYTTVLSIKSFDPDLGINGDVLYHILPSNGSQYFIINQTSGVLKTTWIYDTISFTPLHPKEDIYKISYAAYNQVKSSKNLSSSINSFFYVRIGPYKHFVNNEVFYKYHKRPFFNNIVLLILIGGFTISLSAALIAAIVWAKSKYSTESTSLEQAQANDGKFMMMMMSGELRNTNNTYVYDPYASLIVDADRTIDSGYALSHSRSSTFNSRNNVREHGLINGYDAKTMPRSLIQSNMMHQYPSDPDNQGNSLSTTDLVSSTSATVKHHKPVNKMKSMNSNERDVAGNLK
Sbjct: 1 MPTTMQILPSMLIVSFVLISVISADIFTARFTIPDNNARHSSVGNIISKLPSRFPRGSYQIITRRSSFTKFNQYFRISDSGEIRITKVFDRDDVNNVCGPLGCCDKPSCEIVLDIIVTVIPKNERIPVKVVIVIEDENDNAPDFSESSFTISIFENDATQLDHNLPKALDKDCPIYGIKNYSLSGNKVEYFSLKIRQFQPFLSVKKSFDFENPSEKQFNLSLNAIDNGGKSATLQLIVNVIDINDNPPIFQKKIVNVTIQENTTFPDAILKLNATDLDSGNNAQISYKFSSINRPIIRETFQLQSETGKIYLLKTLDYELYSEQNFDINVLAIDHGSPQLSDSCIIKVNVTDINDNSPVIEIVHSQPIPENEQITDPALKLYVSDYDSIDNDVKCQAEKIGRRLKLEQVEKSSYFIYATEIYDYEKEKNLSLSILCQDSGKEPRYTKQLLTIFIKDVNDNRPKFLRSFYRKSINEDQEKLKPFTKVQALDKDSDDFGKVKYSIGLKDRKYFSIDEISGEVRLANEIDRETKDFYNVSVIATDGGGLKDYSYIEISILDVNDNYPKLKSGSSMRVNENLPVGSVVGYISVIDLDLGDNSKVEWTYDFLGNSSSMLQIENCTVYTSTVLDRESIEHLHILITMVDMGYPRLTSSATITVSVIDENDNIPKVIYPKTGSLVEEREMDHIAVNSPKYTTVLSIKSFDPDLGINGDVLYHILPSNGSQYFIINQTSGVLKTTWIYDTISFTPLHPKEDIYKISYAAYNQVKSSKNLSSSINSFFYVRIGPYKHFVNNEVFYKYHKRPFFNNIVLLILIGGFTISLSAALIAAIVWAKSKYSTESTSLEQAQANDGKFMMMMMSGELRNTNNTYVYDPYASLIVDADRTIDSGYALSHSRSSTFNSRNNVREHGLINGYDAKTMPRSLIQSNMMHQYPSDPDNQGNSLSTTDLVSSTSATVKHHKPVNKMKSMNSNERDVAGNLK 979
BLAST of Protocadherin alpha-2 vs. Planmine SMEST
Match: SMESG000008875.1 (SMESG000008875.1) HSP 1 Score: 491.5 bits (1264), Expect = 2.958e-156 Identity = 306/845 (36.21%), Postives = 466/845 (55.15%), Query Frame = 2
Query: 167 DNNARHSSVGNIISKLPSRFPRGSYQIITRRSSFTKFNQYFRISDSGEIRITKVFDRDDVNNVCGPLGCCDKPSCEIVLDIIVTVIPKNERIPVKVVIVIEDENDNAPDXXXXXXXXXXXXNDATQLDHNLPKALDKDCPIYGIKNYSLSGNKVEYFSLKIRQFQPFLSVKKSFDFENPSEKQFNLSLNAIDNGGKSATLQLIVNVIDINDNPPIFQKKIVNVTIQENTTFPDAILKLNATDLDSGNNAQISYKFSSINRPIIRETFQLQSETGKIYLLKTLDYELYSEQNFDINVLAIDHGSPQLSDSCIIKVNVTDINDNSPVIEIVHSQPIPENEQITDPALKLYVSDYDSIDNDVKCQAEKIGRRLKLEQVEKSSYFIYATEIYDYEKEKNLSLSILCQDSGKEPRYTKQLLTIFIKDVNDNRPKFLRSFYRKSINEDQEKLKPFTKVQALDKDSDDFGKVKYSIGLKDRKYFSIDEISGEVRLANEIDRETKDFYNVSVIATDGGGLKDYSYIEISILDVNDNYPKLKSGSSMRVNENLPVGSVVGYISVIDLDLGDNSKVEWTYDFLGNS--SSMLQIENCTVYTSTVLDRESIEHLHILITMVDMGYPRLTSSATITVSVIDENDNIPKVIYPKTGSLVEEREMDHIAVNSPKYTTVLSIKSFDPDLGINGDVLYHIL-PSNGSQYFIINQTSGVLKTTWIYDTISFTPLHPKEDIYKISYAAYNQVXXXXXXXXXXXXFFYVRIGPYKHFVNNEVFYKYHKRPFFNNIVLLILIGGFTXXXXXXXXXXXVWAKSKYSTESTSLEQAQANDGKFMMMMMSGELRNTNNTYVYDPYASL 2692
DN + ++VGNI L + +Y II S+FTKF+++F++ SG+I TK DRD+ +CGPL CC K CE + I+ + ++ I DENDN P + +LP A D D I G+ NYSLS N ++F L I + P L + + +FEN +E++F+L L A D GG+ T+ L + ID NDN PIF + T++ENTT+ IL++ A DLD G N +ISY+F ++ I + F L TG+I LL+ LDYE+YS+Q + + A+D GSPQLS SC I+++ TDINDNSP IEI+ + IPEN++I P + +YV D DS+ N VKC +L +++S IY +DYE + I C DSG P T + L I I D NDN P F R+ + I+ED + + + A D DS +FGK+ Y + K F I+ +G + L N +DRE K+ V ATDGGGL+ + I+++D+NDN P+LKS + V EN P+G+++G + V DLD G+N++V + N+ S L+++N ++ +++DRE + + + + +VD G P+LTS TIT+S+ID NDN P + YP G ++ R + I VN+ + +L++ + D D NG + + I+ NGS+YF +N+TSG + +TW F P +Y+++ + S + S S FY+ I Y N + FF N+V+L++I F+I L+ L+ AIVWA+++ S +N K + +N ++YDP+ L
Sbjct: 28 DNVPKSTNVGNIFKMLNYQLFNENYHIIVGTSTFTKFHEFFKLFKSGDIITTKFIDRDNREEICGPLSCCSKDICEFQANAILNYQSTKPAVNFQINFEIIDENDNPP-KFNQFKFNINVLEEQKNYRMSLPTAYDLDSSINGVYNYSLSENHKKFFQLSIEKGYPELLILSALNFENVNERKFHLQLTAFDRGGQFETMSLFITTIDRNDNKPIFTDILYRKTVKENTTYTIPILQVQAKDLDEGENGKISYRFDTLTPQEINDKFSLNKLTGEIKLLQKLDYEIYSDQLIEFTIEAVDEGSPQLSGSCKIEIHSTDINDNSPRIEILKNVSIPENKRIATPIMSIYVHDDDSVHNKVKCNKNS-NDNFRLHSSQENSLTIYMERTFDYENSSIHQIDIECFDSGIPPMATYKSLFIAIIDENDNFPIFTRAQHIYQISEDSKVNEFLFQCSATDLDSGNFGKITYRLDDAGNKEFVINISTGYIYLYNSLDREVKEMLEFFVYATDGGGLEASVKVSITVMDINDNPPRLKSPKILTVLENEPIGTLIGNVEVFDLDDGENARVTIENEVQENALFYSYLKLDNNKIFIKSLIDREKVSQIFLRLKLVDHGRPKLTSWETITISIIDINDNDPILEYPSEGDVMNSRSL--IYVNTQFNSFILTLLARDSDFDENGKIRFRIMDDCNGSRYFQVNETSGAIYSTWSCRNGQFISC-PIAGLYRVNIELKDS---SSTIVRSTKSHFYLTIREYSA---NYDLLNVNSNSFFKNVVILVMIVVFSIVLAVGLVGAIVWARTRPSVHFNVCSNESSNSFKKI---------TKSNQWLYDPHLLL 852
BLAST of Protocadherin alpha-2 vs. Planmine SMEST
Match: SMESG000008875.1 (SMESG000008875.1) HSP 1 Score: 491.5 bits (1264), Expect = 3.043e-156 Identity = 306/845 (36.21%), Postives = 466/845 (55.15%), Query Frame = 2
Query: 167 DNNARHSSVGNIISKLPSRFPRGSYQIITRRSSFTKFNQYFRISDSGEIRITKVFDRDDVNNVCGPLGCCDKPSCEIVLDIIVTVIPKNERIPVKVVIVIEDENDNAPDXXXXXXXXXXXXNDATQLDHNLPKALDKDCPIYGIKNYSLSGNKVEYFSLKIRQFQPFLSVKKSFDFENPSEKQFNLSLNAIDNGGKSATLQLIVNVIDINDNPPIFQKKIVNVTIQENTTFPDAILKLNATDLDSGNNAQISYKFSSINRPIIRETFQLQSETGKIYLLKTLDYELYSEQNFDINVLAIDHGSPQLSDSCIIKVNVTDINDNSPVIEIVHSQPIPENEQITDPALKLYVSDYDSIDNDVKCQAEKIGRRLKLEQVEKSSYFIYATEIYDYEKEKNLSLSILCQDSGKEPRYTKQLLTIFIKDVNDNRPKFLRSFYRKSINEDQEKLKPFTKVQALDKDSDDFGKVKYSIGLKDRKYFSIDEISGEVRLANEIDRETKDFYNVSVIATDGGGLKDYSYIEISILDVNDNYPKLKSGSSMRVNENLPVGSVVGYISVIDLDLGDNSKVEWTYDFLGNS--SSMLQIENCTVYTSTVLDRESIEHLHILITMVDMGYPRLTSSATITVSVIDENDNIPKVIYPKTGSLVEEREMDHIAVNSPKYTTVLSIKSFDPDLGINGDVLYHIL-PSNGSQYFIINQTSGVLKTTWIYDTISFTPLHPKEDIYKISYAAYNQVXXXXXXXXXXXXFFYVRIGPYKHFVNNEVFYKYHKRPFFNNIVLLILIGGFTXXXXXXXXXXXVWAKSKYSTESTSLEQAQANDGKFMMMMMSGELRNTNNTYVYDPYASL 2692
DN + ++VGNI L + +Y II S+FTKF+++F++ SG+I TK DRD+ +CGPL CC K CE + I+ + ++ I DENDN P + +LP A D D I G+ NYSLS N ++F L I + P L + + +FEN +E++F+L L A D GG+ T+ L + ID NDN PIF + T++ENTT+ IL++ A DLD G N +ISY+F ++ I + F L TG+I LL+ LDYE+YS+Q + + A+D GSPQLS SC I+++ TDINDNSP IEI+ + IPEN++I P + +YV D DS+ N VKC +L +++S IY +DYE + I C DSG P T + L I I D NDN P F R+ + I+ED + + + A D DS +FGK+ Y + K F I+ +G + L N +DRE K+ V ATDGGGL+ + I+++D+NDN P+LKS + V EN P+G+++G + V DLD G+N++V + N+ S L+++N ++ +++DRE + + + + +VD G P+LTS TIT+S+ID NDN P + YP G ++ R + I VN+ + +L++ + D D NG + + I+ NGS+YF +N+TSG + +TW F P +Y+++ + S + S S FY+ I Y N + FF N+V+L++I F+I L+ L+ AIVWA+++ S +N K + +N ++YDP+ L
Sbjct: 28 DNVPKSTNVGNIFKMLNYQLFNENYHIIVGTSTFTKFHEFFKLFKSGDIITTKFIDRDNREEICGPLSCCSKDICEFQANAILNYQSTKPAVNFQINFEIIDENDNPP-KFNQFKFNINVLEEQKNYRMSLPTAYDLDSSINGVYNYSLSENHKKFFQLSIEKGYPELLILSALNFENVNERKFHLQLTAFDRGGQFETMSLFITTIDRNDNKPIFTDILYRKTVKENTTYTIPILQVQAKDLDEGENGKISYRFDTLTPQEINDKFSLNKLTGEIKLLQKLDYEIYSDQLIEFTIEAVDEGSPQLSGSCKIEIHSTDINDNSPRIEILKNVSIPENKRIATPIMSIYVHDDDSVHNKVKCNKNS-NDNFRLHSSQENSLTIYMERTFDYENSSIHQIDIECFDSGIPPMATYKSLFIAIIDENDNFPIFTRAQHIYQISEDSKVNEFLFQCSATDLDSGNFGKITYRLDDAGNKEFVINISTGYIYLYNSLDREVKEMLEFFVYATDGGGLEASVKVSITVMDINDNPPRLKSPKILTVLENEPIGTLIGNVEVFDLDDGENARVTIENEVQENALFYSYLKLDNNKIFIKSLIDREKVSQIFLRLKLVDHGRPKLTSWETITISIIDINDNDPILEYPSEGDVMNSRSL--IYVNTQFNSFILTLLARDSDFDENGKIRFRIMDDCNGSRYFQVNETSGAIYSTWSCRNGQFISC-PIAGLYRVNIELKDS---SSTIVRSTKSHFYLTIREYSA---NYDLLNVNSNSFFKNVVILVMIVVFSIVLAVGLVGAIVWARTRPSVHFNVCSNESSNSFKKI---------TKSNQWLYDPHLLL 852
BLAST of Protocadherin alpha-2 vs. Planmine SMEST
Match: SMESG000008875.1 (SMESG000008875.1) HSP 1 Score: 490.73 bits (1262), Expect = 3.154e-156 Identity = 306/845 (36.21%), Postives = 466/845 (55.15%), Query Frame = 2
Query: 167 DNNARHSSVGNIISKLPSRFPRGSYQIITRRSSFTKFNQYFRISDSGEIRITKVFDRDDVNNVCGPLGCCDKPSCEIVLDIIVTVIPKNERIPVKVVIVIEDENDNAPDXXXXXXXXXXXXNDATQLDHNLPKALDKDCPIYGIKNYSLSGNKVEYFSLKIRQFQPFLSVKKSFDFENPSEKQFNLSLNAIDNGGKSATLQLIVNVIDINDNPPIFQKKIVNVTIQENTTFPDAILKLNATDLDSGNNAQISYKFSSINRPIIRETFQLQSETGKIYLLKTLDYELYSEQNFDINVLAIDHGSPQLSDSCIIKVNVTDINDNSPVIEIVHSQPIPENEQITDPALKLYVSDYDSIDNDVKCQAEKIGRRLKLEQVEKSSYFIYATEIYDYEKEKNLSLSILCQDSGKEPRYTKQLLTIFIKDVNDNRPKFLRSFYRKSINEDQEKLKPFTKVQALDKDSDDFGKVKYSIGLKDRKYFSIDEISGEVRLANEIDRETKDFYNVSVIATDGGGLKDYSYIEISILDVNDNYPKLKSGSSMRVNENLPVGSVVGYISVIDLDLGDNSKVEWTYDFLGNS--SSMLQIENCTVYTSTVLDRESIEHLHILITMVDMGYPRLTSSATITVSVIDENDNIPKVIYPKTGSLVEEREMDHIAVNSPKYTTVLSIKSFDPDLGINGDVLYHIL-PSNGSQYFIINQTSGVLKTTWIYDTISFTPLHPKEDIYKISYAAYNQVXXXXXXXXXXXXFFYVRIGPYKHFVNNEVFYKYHKRPFFNNIVLLILIGGFTXXXXXXXXXXXVWAKSKYSTESTSLEQAQANDGKFMMMMMSGELRNTNNTYVYDPYASL 2692
DN + ++VGNI L + +Y II S+FTKF+++F++ SG+I TK DRD+ +CGPL CC K CE + I+ + ++ I DENDN P + +LP A D D I G+ NYSLS N ++F L I + P L + + +FEN +E++F+L L A D GG+ T+ L + ID NDN PIF + T++ENTT+ IL++ A DLD G N +ISY+F ++ I + F L TG+I LL+ LDYE+YS+Q + + A+D GSPQLS SC I+++ TDINDNSP IEI+ + IPEN++I P + +YV D DS+ N VKC +L +++S IY +DYE + I C DSG P T + L I I D NDN P F R+ + I+ED + + + A D DS +FGK+ Y + K F I+ +G + L N +DRE K+ V ATDGGGL+ + I+++D+NDN P+LKS + V EN P+G+++G + V DLD G+N++V + N+ S L+++N ++ +++DRE + + + + +VD G P+LTS TIT+S+ID NDN P + YP G ++ R + I VN+ + +L++ + D D NG + + I+ NGS+YF +N+TSG + +TW F P +Y+++ + S + S S FY+ I Y N + FF N+V+L++I F+I L+ L+ AIVWA+++ S +N K + +N ++YDP+ L
Sbjct: 5 DNVPKSTNVGNIFKMLNYQLFNENYHIIVGTSTFTKFHEFFKLFKSGDIITTKFIDRDNREEICGPLSCCSKDICEFQANAILNYQSTKPAVNFQINFEIIDENDNPP-KFNQFKFNINVLEEQKNYRMSLPTAYDLDSSINGVYNYSLSENHKKFFQLSIEKGYPELLILSALNFENVNERKFHLQLTAFDRGGQFETMSLFITTIDRNDNKPIFTDILYRKTVKENTTYTIPILQVQAKDLDEGENGKISYRFDTLTPQEINDKFSLNKLTGEIKLLQKLDYEIYSDQLIEFTIEAVDEGSPQLSGSCKIEIHSTDINDNSPRIEILKNVSIPENKRIATPIMSIYVHDDDSVHNKVKCNKNS-NDNFRLHSSQENSLTIYMERTFDYENSSIHQIDIECFDSGIPPMATYKSLFIAIIDENDNFPIFTRAQHIYQISEDSKVNEFLFQCSATDLDSGNFGKITYRLDDAGNKEFVINISTGYIYLYNSLDREVKEMLEFFVYATDGGGLEASVKVSITVMDINDNPPRLKSPKILTVLENEPIGTLIGNVEVFDLDDGENARVTIENEVQENALFYSYLKLDNNKIFIKSLIDREKVSQIFLRLKLVDHGRPKLTSWETITISIIDINDNDPILEYPSEGDVMNSRSL--IYVNTQFNSFILTLLARDSDFDENGKIRFRIMDDCNGSRYFQVNETSGAIYSTWSCRNGQFISC-PIAGLYRVNIELKDS---SSTIVRSTKSHFYLTIREYSA---NYDLLNVNSNSFFKNVVILVMIVVFSIVLAVGLVGAIVWARTRPSVHFNVCSNESSNSFKKIT---------KSNQWLYDPHLLL 829 The following BLAST results are available for this feature:
BLAST of Protocadherin alpha-2 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of Protocadherin alpha-2 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of Protocadherin alpha-2 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of Protocadherin alpha-2 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of Protocadherin alpha-2 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of Protocadherin alpha-2 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of Protocadherin alpha-2 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of Protocadherin alpha-2 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Protocadherin alpha-2 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of Protocadherin alpha-2 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 5
BLAST of Protocadherin alpha-2 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 0
BLAST of Protocadherin alpha-2 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of Protocadherin alpha-2 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of Protocadherin alpha-2 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30028328 ID=SMED30028328|Name=Protocadherin alpha-2|organism=Schmidtea mediterranea sexual|type=transcript|length=3359bpback to top protein sequence of SMED30028328-orf-1 >SMED30028328-orf-1 ID=SMED30028328-orf-1|Name=SMED30028328-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=1051bp MMPTTMQILPSMLIVSFVLISVISADIFTARFTIPDNNARHSSVGNIISKback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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