Protein tyrosine phosphatase receptor type D
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30028312 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 16Note: Hover over icons to view figure legend
Homology
BLAST of Protein tyrosine phosphatase receptor type D vs. Ensembl Human
Match: PTPRS (protein tyrosine phosphatase receptor type S [Source:HGNC Symbol;Acc:HGNC:9681]) HSP 1 Score: 720.694 bits (1859), Expect = 0.000e+0 Identity = 341/635 (53.70%), Postives = 449/635 (70.71%), Query Frame = 1
Query: 3928 KSIPDLVNADS---VQMCQDGTKLSPVLVSDSIKLRIGSQKSENISDRPSISICNLYQYVTDLKANDCTLLQAEFETLNTNLDDRFTWQRSNIDSNKSKNRYANVVAYDHTSVLLTPVDDVIGSDYINANYIDGYQRQNAYIATQGPLPDTTDDFWRMVWEQRSNCIVMMTRLEERSGIKCHQYWPNRGFICYGQMIVSHIDTFVLAYYTIRLFEIRHSKYSEKREIQHFQFTAWPDHGVPKLSTPLLMFIRRVRSIGKIESCPKIVHCSAGVGRTGAFIVVDAQLERIKQEKNIDVFNYVSKIRCQRNYMVQTQAQYQFILETLLEAVEDGNTEVMACNFHAHVTKLSQIGISGSNQLSGFEMEFSKLNSLASNRGRHGVMLADFVKAAGNQAVNMTKNRVRNIIPYEWNRVVLNAIRGIEGSDYINASYIDGYRDRRAYIAAQSPIPSTVEDFWRMLWDQHCGVVIVLNQPHE---DKSHIYWPINKSIRYQFFVVDPVVEYNMPNYILREFKVTDARDGEFRALRQFQFTQWPNHGCPKESESILDFIRQVHKTKEQFGHMEPMVIHCNTGSGRTGVFIALSIVLDRLQQESVVDMYQTVKLLHKQRIGLVQTEEQYEFCYMAVLDYLSNYE 5814
K+ PD DS + + L+P D +++R + ++ + P I I ++ ++ LKAND L E+E+++ +FTW+ SN++ NK KNRYANV+AYDH+ V+L P++ ++GSDYINANY+DGY+ QNAYIATQGPLP+T DFWRMVWEQRS IVMMTRLEE+S IKC QYWPNRG YG + V+ +DT LA + +R F + + SEKRE++ FQFTAWPDHGVP+ TP L F+RRV++ ++ P +VHCSAGVGRTG FIV+DA LERIK EK +DV+ +V+ +R QRNYMVQT+ QY FI E LLEAV GNTEV A + +A++ KL+Q + ++G E+EF +L + ++ R F+ A N N KNR+ NI+PYE RV L IRG+EGSDYINAS+IDGYR ++AYIA Q P+ T EDFWRMLW+ + +V++L + E +K H YWP +S RYQ+FVVDP+ EYNMP YILREFKVTDARDG+ R +RQFQFT WP G PK E +DFI QVHKTKEQFG P+ +HC+ G GRTGVFI LSIVL+R++ E VVD++QTVK+L QR +VQTE++Y+FCY A L+YL +++
Sbjct: 1285 KNKPDSKRKDSEPRTKCLLNNADLAPHHPKDPVEMRRINFQTPGMLSHPPIPIADMAEHTERLKANDSLKLSQEYESIDPG--QQFTWEHSNLEVNKPKNRYANVIAYDHSRVILQPIEGIMGSDYINANYVDGYRCQNAYIATQGPLPETFGDFWRMVWEQRSATIVMMTRLEEKSRIKCDQYWPNRGTETYGFIQVTLLDTIELATFCVRTFSLHKNGSSEKREVRQFQFTAWPDHGVPEYPTPFLAFLRRVKTCNPPDAGPIVVHCSAGVGRTGCFIVIDAMLERIKPEKTVDVYGHVTLMRSQRNYMVQTEDQYSFIHEALLEAVGCGNTEVPARSLYAYIQKLAQ--VEPGEHVTGMELEFKRLANSKAHTSR-------FISA--NLPCNKFKNRLVNIMPYESTRVCLQPIRGVEGSDYINASFIDGYRQQKAYIATQGPLAETTEDFWRMLWENNSTIVVMLTKLREMGREKCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDARDGQSRTVRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKEQFGQDGPISVHCSAGVGRTGVFITLSIVLERMRYEGVVDIFQTVKMLRTQRPAMVQTEDEYQFCYQAALEYLGSFD 1906 HSP 2 Score: 205.297 bits (521), Expect = 4.172e-52 Identity = 105/262 (40.08%), Postives = 151/262 (57.63%), Query Frame = 1
Query: 5092 NQAVNMTKNRVRNIIPYEWNRVVLNAIRGIEGSDYINASYIDGYRDRRAYIAAQSPIPSTVEDFWRMLWDQHCGVVIVLNQPHEDKSHI----YWPINKSIRYQFFVVDPVVEYNMPNYILREFKVTDARDGEFRALRQFQFTQWPNHGCPKESESILDFIRQVHKTKEQFGHMEPMVIHCNTGSGRTGVFIALSIVLDRLQQESVVDMYQTVKLLHKQRIGLVQTEEQYEFCYMAVLDYLSNYEKILEKSHLY*TYQDLSE 5865
N VN KNR N+I Y+ +RV+L I GI GSDYINA+Y+DGYR + AYIA Q P+P T DFWRM+W+Q ++++ + E+KS I YWP + Y F V + + + +R F + E R +RQFQFT WP+HG P+ L F+R+V P+V+HC+ G GRTG FI + +L+R++ E VD+Y V L+ QR +VQTE+QY F + A+L+ + + LY Q L++
Sbjct: 1374 NLEVNKPKNRYANVIAYDHSRVILQPIEGIMGSDYINANYVDGYRCQNAYIATQGPLPETFGDFWRMVWEQRSATIVMMTR-LEEKSRIKCDQYWPNRGTETYGFIQVTLLDTIELATFCVRTFSLHKNGSSEKREVRQFQFTAWPDHGVPEYPTPFLAFLRRVKTCNPP--DAGPIVVHCSAGVGRTGCFIVIDAMLERIKPEKTVDVYGHVTLMRSQRNYMVQTEDQYSFIHEALLEAVGCGNTEVPARSLYAYIQKLAQ 1632 HSP 3 Score: 160.614 bits (405), Expect = 1.451e-38 Identity = 223/951 (23.45%), Postives = 376/951 (39.54%), Query Frame = 1
Query: 370 LACSSTGHPVPSISW-----KINESPIEELKSPLKKLQNPPRIFSIKNYQNSVLVITQLIESDSNSVLICEAENNAGFDSRQQQLKVISTETDIPSGFPVFQNNFFPIIKPYNSNVTLVCQAYGNPPPLIQWFKNYELINESFT--KIKILNDGNLLLVQVTREDKGIYHCQAQNTNGLRLSDPSTLDITSYPISPNSLII----ERFASDNVEIS------------WRSGLNDVTEQENFILHYREVPENITEKQIMSKFVYLTISEKKSIYKYNLKDLFPFTTYCIWMESENPLGVSPPTIALTVKTLPTSPQLSPRSITATSISNTAILVAWRPPERKFGKFKYYQIIYTNNDGFLPQHWRQFAVKDDNVMLTHLIAS----ELYHIRVKIVNEIGHGPLSKTISIKTIAGTLSQCP-DFKITEIFQSHIKLQWGTPDPVKLFKLIQYNLLCWDVRLKIVNATAKSSTLFPILN---HNLSMNEMEYVLYLKNEKEIKCRLSAINSDGKG-MPTEIQASTVNKGVNYQNL-IHIDKIGSTYITFQWRPPSKFSFDYFLWIYQIFDSEKLDRAVKLPKIKINISDSASAENGWFVYNYTNAFS-SSRYILGLRYLCRDSTDILREYVHRSDLVSTMKSVPSDSPKDLVVKEIDSNSALVSWKPLDQVHSNGIITHYEVRYYAPKKEESTERFIN---VSETSAILSNL-KYFHYVIYVRAFTKVGGGSWSNPKNYYRQNLEEFP--IPTTIKGERKSETEINISWELPVLSEKNLAHAAIEGFIILYAPVESS----PKWIKYTVQSKNLSAVIKGLEPDLRYQFQIAATNYAGFNGNFSE----IVQEMPKNFPNLNLKTVPDLRCSVQSSNRLKVEWSSPSISTDLLKFEIRYSGNLSYITEIGLKKSEFIDMESKSVNFETLVNRYDVTLENLQSNALYKIAVRA 3078
C +TG P P ++W K+N E ++ +VL I L +V C A+N+ G + +L V+ E +PSGFP + T++C A GNP P I WFK++ ++ S + +IK L G L + D+G Y C A N+ G+R S P+ L + ++P I+ E NV I+ W G D+T +++ V N+ E LT ++KD +T C+ M S LGV +TVK+LP +P + T + T+I + W YY I Y + P + +K+D + I Y I V VN IG GP S+++ +T + P + + + + + +QW +PV+ LI+ + + + + P+ N HN+ + + V L ++ R+ A S G G + IQ T +GV Q + + + T IT W PP + S + +++ D + P + D N AF ++R GL T ++R+ T++S PS P+D+ + S + LVSW+P NG + Y VRY E+ + +N + T +L L K+ Y I A T+VG G S+P + E+ P P ++ E + T I + W P + H I G+ + Y +E + P IK + + VI L+P+ Y +AA G +G S+ + + P L+++ P+ L W P+ + + L Y + G + S + ++ F +RY + + + ++++A R+
Sbjct: 52 FVCQATGDPKPRVTWNKKGKKVNSQRFETIE--------------FDESAGAVLRIQPLRTPRDENVYECVAQNSVGEITVHAKLTVLR-EDQLPSGFPNIDMGPQLKVVERTRTATMLCAASGNPDPEITWFKDFLPVDPSASNGRIKQLRSGALQIESSEETDQGKYECVATNSAGVRYSSPANLYVRVRRVAPRFSILPMSHEIMPGGNVNITCVAVGSPMPYVKWMQGAEDLTPEDDM-----PVGRNVLE---------LT----------DVKDSANYT--CVAMSS---LGVIEAVAQITVKSLPKAPG----TPMVTENTATSITITWD--SGNPDPVSYYVIEYKSKSQDGP-----YQIKEDITTTRYSIGGLSPNSEYEIWVSAVNSIGQGPPSESVVTRTGEQAPASAPRNVQARMLSATTMIVQWE--EPVEPNGLIRGYRVYYTMEPE-----------HPVGNWQKHNVDDSLLTTVGSLLEDETYTVRVLAFTSVGDGPLSDPIQVKT-QQGVPGQPMNLRAEARSETSITLSWSPPRQESIIKYELLFREGDHGREVGRTFDPTTSYVVED--------LKPNTEYAFRLAARSPQGLGAF----TPVVRQ--------RTLQSKPSAPPQDVKCVSVRSTAILVSWRPPPPETHNGALVGYSVRYRPLGSEDPEPKEVNGIPPTTTQILLEALEKWTQYRITTVAHTEVGPGPESSP--VVVRTDEDVPSAPPRKVEAEALNATAIRVLWRSPAPGRQ---HGQIRGYQVHYVRMEGAEARGPPRIKDVMLADAQEMVITNLQPETAYSITVAAYTMKG-DGARSKPKVVVTKGAVLGRPTLSVQQTPE--------GSLLARWEPPAGTAE--------DQVLGYRLQFGREDSTPL----ATLEFPPSEDRYTASGVHKGATYVFRLAARS 887 HSP 4 Score: 150.984 bits (380), Expect = 1.373e-35 Identity = 209/970 (21.55%), Postives = 390/970 (40.21%), Query Frame = 1
Query: 268 VLINSQITFTENDEAPK----ISLIIQSPNVLLFKSMILACSSTGHPVPSISWKINESPIEELKSPLKKLQNPPRIFSIKNYQNSVLVITQLIESDSNSVLICEAENNAGFDSRQQQLKVISTETDIPSGFPVFQNNFFPI---IKPYNSNVTLVCQAYGNPPPLIQWFKNYELINESFTKIKILNDGNLLLVQVTREDKGIYHCQAQNTNGLRLSDPSTLDITSYPISPNSLIIERFASDNVEISWRSGLNDVTEQENFILHYREVPENITEKQIMSKFVYLTISEKKSIYKYNLKDLFPFTTYCIWMESENPLGVSPPTIALTVKTLPTSPQLSPRSITATSISNTAILVAWRPPERKFGKFKYYQIIYTNNDGFLPQHWRQFAVKDDNVMLT--HLIASELYHIRVKIVNEIGHGPLSKTISIKTIAGTLSQCPDFKITEIFQSHIKLQWGTPDPVKLFKLIQYNLLCWDV-RLKIVNATAKSSTLFPILNHNLSMNEMEYVLYLKNEKEIKCRLSAINSDGKGMPTEI--QASTVNKGVNYQNLIHIDKIGSTYITFQWRPPSKFSFDYFLWIYQIFDSEKLDRAVKLPKIKINISDSAS-----AENGWFVYNYTNAFSSSRYILGLRYLCRDSTDILREYVHRSDLVSTMKSVPSDSPKDLVVKEIDSNSALVSWKPLDQVHSNGIITHYEVRYYAPKKEES--TERFINVSETSA---ILSNLK-YFHYVIYVRAFTKVGGGSWSNPKNYYRQN-LEEFPIPTTIKGERKSETEINISWELPVLSEKNLAHAAIEGFIILYAPVESSP-KWIKYTVQSKNLSAVIKGLEPDLRYQFQIAATNYAGFNGNFSEIV---QEMPKNFPNLNLKTVPDLRCSVQSSNRLKVEWSSPSIS---TDLLKF--EIRYSGNLSYITEIGLKKSEFIDMESKSVNFETLVNRYDVTLENLQSNALYKIAVRA 3078
+ +++++T D+ P I + Q V ++ + C+++G+P P I+W + P++ S + IK ++ L I E+D C A N+AG + P + + P+ I P NV + C A G+P P ++W + E T + G +L +D Y C A ++ G+ + + + + S P +P + ++ + ++ I+W SG D +++ Y+ S+ I E + +Y++ L P + Y IW+ + N +G PP+ ++ +T +P +PR++ A +S T ++V W P G + Y++ YT +W++ V DD+++ T L+ E Y +RV +G GPLS I +KT G Q + + ++ I L W P + +I+Y LL + + V T +T + + + LK E RL+A + G G T + Q + +K + + ST I WRPP + + L Y + L PK I + + A W Y T T++ +V T + VPS P+ + + +++ + V W+ +G I Y+V Y + E+ R +V A +++NL+ Y I V A+T G G+ S PK + + P T+ ++ E + WE P A + G+ + + +S+P +++ +A G+ Y F++AA + G +E++ ++ P+ P + L+ + S+ + + W P + ++K+ +R +G L E L + E+ +TL+ L+ + Y + VRA
Sbjct: 116 ITVHAKLTVLREDQLPSGFPNIDMGPQLKVVERTRTATMLCAASGNPDPEITWFKDFLPVDPSASNGR----------IKQLRSGALQIESSEETDQGK-YECVATNSAGVRYSSPANLYVRVRRVAP------RFSILPMSHEIMP-GGNVNITCVAVGSPMPYVKWMQG----AEDLTPEDDMPVGRNVLELTDVKDSANYTCVAMSSLGV-IEAVAQITVKSLPKAPGTPMVTENTATSITITWDSGNPDPVSY--YVIEYKS----------KSQDGPYQIKEDITTTRYSIGGLSPNSEYEIWVSAVNSIGQGPPSESVVTRTGEQAPASAPRNVQARMLSATTMIVQWEEPVEPNGLIRGYRVYYTMEPEHPVGNWQKHNV-DDSLLTTVGSLLEDETYTVRVLAFTSVGDGPLSDPIQVKTQQGVPGQPMNLRAEARSETSITLSWSPP---RQESIIKYELLFREGDHGREVGRTFDPTTSYVVED-------------LKPNTEYAFRLAARSPQGLGAFTPVVRQRTLQSKPSAPPQDVKCVSVRSTAILVSWRPPPPETHNGALVGYSV-RYRPLGSEDPEPKEVNGIPPTTTQILLEALEKWTQYRITTV---------------AHTEVGPGPESSPVVVRTDEDVPSAPPRKVEAEALNATAIRVLWRSPAPGRQHGQIRGYQVHYVRMEGAEARGPPRIKDVMLADAQEMVITNLQPETAYSITVAAYTMKGDGARSKPKVVVTKGAVLGRP---TLSVQQTPEGSLLARWEPPA----GTAEDQVLGYRLQFGREDSTPLATLEFPPSEDRYTA--SGVHKGATYVFRLAARSRGGLGEEAAEVLSIPEDTPRGHPQI-LEAAGN-----ASAGTVLLRWLPPVPAERNGAIVKYTVAVREAGALGPARETELPAAAEPGAENA------------LTLQGLKPDTAYDLQVRA 990 HSP 5 Score: 90.8929 bits (224), Expect = 2.520e-17 Identity = 125/573 (21.82%), Postives = 218/573 (38.05%), Query Frame = 1
Query: 889 LSDPSTLDIT-SYPISPNSLIIERFASDNVEISWRSGLNDVTEQENFILHYREVPENITEKQIMSKFVYLTISEKKSIYKYNLKDLFPFTTYCIWMESENPLGVSPPTIALTVKTLPTSPQLSPRSITATSISNTAILVAWRPP--ERKFGKFKYYQIIYT--NNDGFLPQHWRQFAVKDDNVMLTHLIASELYHIRVKIVNEIGHGPLSKTISIKTIAGTLSQCP-DFKITEIFQSHIKLQWGTPDPVKLFKLIQYNLLCWDVRLKIVNATAKSSTLFPILNHNLSMNEMEYVLY-LKNEKEIKCRLSAINSDGKGMPTEIQASTVNKGVNYQNLIHIDKIGSTYITFQWRPPSKFSFDYFLWIYQIFDSEKLDRAVKLPKIKINISDSASAENGWFVYNYTNAFSSSRYILGLRYLCRDSTDILREYVHRSDLVSTMKSVPSDSPKDL-VVKEIDSNSALVSWKPLDQVHSNGIITHY-----EVRYYAPKKE-ESTERFINVSETSAILSNLKY-FHYVIYVRAFTKVGGGSWSNPKNYYRQNLEEFPIPTTIKGERKSETEINISWELP 2562
LSDP + P P +L E + ++ +SW QE+ I + E +++ F T Y ++DL P T Y + + +P G+ T + +TL + P P+ + S+ +TAILV+WRPP E G Y + Y ++ P+ ++L L Y I E+G GP S + ++T S P + + + I++ W +P P + I+ + + VR++ A P + + + E V+ L+ E ++A G G ++ + V + + + + + +W PP+ + D L F E + L ++ S+ Y + + Y+ R R + E ++++S + P P+ L + + L+ W P NG I Y E P +E E +E + L LK Y + VRA T+ G G +S P Y R L + P K + +T + +SWE P
Sbjct: 499 LSDPIQVKTQQGVPGQPMNLRAEARSETSITLSWSP-----PRQESIIKYELLFREGDHGREVGRTFDPTT--------SYVVEDLKPNTEYAFRLAARSPQGLGAFTPVVRQRTLQSKPSAPPQDVKCVSVRSTAILVSWRPPPPETHNGALVGYSVRYRPLGSEDPEPKEVNGIPPTTTQILLEALEKWTQYRITTVAHTEVGPGPESSPVVVRTDEDVPSAPPRKVEAEALNATAIRVLWRSPAPGRQHGQIRGYQVHY-VRMEGAEARGP-----PRIKDVMLADAQEMVITNLQPETAYSITVAAYTMKGDGARSKPKVVVTKGAVLGRPTLSVQQTPEGSLLARWEPPAGTAEDQVLGYRLQFGRED---STPLATLEFPPSEDR--------YTASGVHKGATYVF--RLAARSRGGLGEEA---AEVLSIPEDTPRGHPQILEAAGNASAGTVLLRWLPPVPAERNGAIVKYTVAVREAGALGPARETELPAAAEPGAENALTLQGLKPDTAYDLQVRAHTRRGPGPFSPPVRY-RTFLRDQVSPKNFKVKMIMKTSVLLSWEFP 1035
BLAST of Protein tyrosine phosphatase receptor type D vs. Ensembl Human
Match: PTPRS (protein tyrosine phosphatase receptor type S [Source:HGNC Symbol;Acc:HGNC:9681]) HSP 1 Score: 717.613 bits (1851), Expect = 0.000e+0 Identity = 341/635 (53.70%), Postives = 449/635 (70.71%), Query Frame = 1
Query: 3928 KSIPDLVNADS---VQMCQDGTKLSPVLVSDSIKLRIGSQKSENISDRPSISICNLYQYVTDLKANDCTLLQAEFETLNTNLDDRFTWQRSNIDSNKSKNRYANVVAYDHTSVLLTPVDDVIGSDYINANYIDGYQRQNAYIATQGPLPDTTDDFWRMVWEQRSNCIVMMTRLEERSGIKCHQYWPNRGFICYGQMIVSHIDTFVLAYYTIRLFEIRHSKYSEKREIQHFQFTAWPDHGVPKLSTPLLMFIRRVRSIGKIESCPKIVHCSAGVGRTGAFIVVDAQLERIKQEKNIDVFNYVSKIRCQRNYMVQTQAQYQFILETLLEAVEDGNTEVMACNFHAHVTKLSQIGISGSNQLSGFEMEFSKLNSLASNRGRHGVMLADFVKAAGNQAVNMTKNRVRNIIPYEWNRVVLNAIRGIEGSDYINASYIDGYRDRRAYIAAQSPIPSTVEDFWRMLWDQHCGVVIVLNQPHE---DKSHIYWPINKSIRYQFFVVDPVVEYNMPNYILREFKVTDARDGEFRALRQFQFTQWPNHGCPKESESILDFIRQVHKTKEQFGHMEPMVIHCNTGSGRTGVFIALSIVLDRLQQESVVDMYQTVKLLHKQRIGLVQTEEQYEFCYMAVLDYLSNYE 5814
K+ PD DS + + L+P D +++R + ++ + P I I ++ ++ LKAND L E+E+++ +FTW+ SN++ NK KNRYANV+AYDH+ V+L P++ ++GSDYINANY+DGY+ QNAYIATQGPLP+T DFWRMVWEQRS IVMMTRLEE+S IKC QYWPNRG YG + V+ +DT LA + +R F + + SEKRE++ FQFTAWPDHGVP+ TP L F+RRV++ ++ P +VHCSAGVGRTG FIV+DA LERIK EK +DV+ +V+ +R QRNYMVQT+ QY FI E LLEAV GNTEV A + +A++ KL+Q + ++G E+EF +L + ++ R F+ A N N KNR+ NI+PYE RV L IRG+EGSDYINAS+IDGYR ++AYIA Q P+ T EDFWRMLW+ + +V++L + E +K H YWP +S RYQ+FVVDP+ EYNMP YILREFKVTDARDG+ R +RQFQFT WP G PK E +DFI QVHKTKEQFG P+ +HC+ G GRTGVFI LSIVL+R++ E VVD++QTVK+L QR +VQTE++Y+FCY A L+YL +++
Sbjct: 880 KNKPDSKRKDSEPRTKCLLNNADLAPHHPKDPVEMRRINFQTPGMLSHPPIPIADMAEHTERLKANDSLKLSQEYESIDPG--QQFTWEHSNLEVNKPKNRYANVIAYDHSRVILQPIEGIMGSDYINANYVDGYRCQNAYIATQGPLPETFGDFWRMVWEQRSATIVMMTRLEEKSRIKCDQYWPNRGTETYGFIQVTLLDTIELATFCVRTFSLHKNGSSEKREVRQFQFTAWPDHGVPEYPTPFLAFLRRVKTCNPPDAGPIVVHCSAGVGRTGCFIVIDAMLERIKPEKTVDVYGHVTLMRSQRNYMVQTEDQYSFIHEALLEAVGCGNTEVPARSLYAYIQKLAQ--VEPGEHVTGMELEFKRLANSKAHTSR-------FISA--NLPCNKFKNRLVNIMPYESTRVCLQPIRGVEGSDYINASFIDGYRQQKAYIATQGPLAETTEDFWRMLWENNSTIVVMLTKLREMGREKCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDARDGQSRTVRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKEQFGQDGPISVHCSAGVGRTGVFITLSIVLERMRYEGVVDIFQTVKMLRTQRPAMVQTEDEYQFCYQAALEYLGSFD 1501 HSP 2 Score: 204.527 bits (519), Expect = 4.292e-52 Identity = 105/262 (40.08%), Postives = 151/262 (57.63%), Query Frame = 1
Query: 5092 NQAVNMTKNRVRNIIPYEWNRVVLNAIRGIEGSDYINASYIDGYRDRRAYIAAQSPIPSTVEDFWRMLWDQHCGVVIVLNQPHEDKSHI----YWPINKSIRYQFFVVDPVVEYNMPNYILREFKVTDARDGEFRALRQFQFTQWPNHGCPKESESILDFIRQVHKTKEQFGHMEPMVIHCNTGSGRTGVFIALSIVLDRLQQESVVDMYQTVKLLHKQRIGLVQTEEQYEFCYMAVLDYLSNYEKILEKSHLY*TYQDLSE 5865
N VN KNR N+I Y+ +RV+L I GI GSDYINA+Y+DGYR + AYIA Q P+P T DFWRM+W+Q ++++ + E+KS I YWP + Y F V + + + +R F + E R +RQFQFT WP+HG P+ L F+R+V P+V+HC+ G GRTG FI + +L+R++ E VD+Y V L+ QR +VQTE+QY F + A+L+ + + LY Q L++
Sbjct: 969 NLEVNKPKNRYANVIAYDHSRVILQPIEGIMGSDYINANYVDGYRCQNAYIATQGPLPETFGDFWRMVWEQRSATIVMMTR-LEEKSRIKCDQYWPNRGTETYGFIQVTLLDTIELATFCVRTFSLHKNGSSEKREVRQFQFTAWPDHGVPEYPTPFLAFLRRVKTCNPP--DAGPIVVHCSAGVGRTGCFIVIDAMLERIKPEKTVDVYGHVTLMRSQRNYMVQTEDQYSFIHEALLEAVGCGNTEVPARSLYAYIQKLAQ 1227 HSP 3 Score: 127.872 bits (320), Expect = 1.459e-28 Identity = 128/568 (22.54%), Postives = 241/568 (42.43%), Query Frame = 1
Query: 268 VLINSQITFTENDEAPK----ISLIIQSPNVLLFKSMILACSSTGHPVPSISWKINESPIEELKSPLKKLQNPPRIFSIKNYQNSVLVITQLIESDSNSVLICEAENNAGFDSRQQQLKVISTETDIPSGFPVFQNNFFPI---IKPYNSNVTLVCQAYGNPPPLIQWFKNYELINESFTKIKILNDGNLLLVQVTREDKGIYHCQAQNTNGLRLSDPSTLDITSYPISPNSLIIERFASDNVEISWRSGLNDVTEQENFILHYREVPENITEKQIMSKFVYLTISEKKSIYKYNLKDLFPFTTYCIWMESENPLGVSPPTIALTVKTLPTSPQLSPRSITATSISNTAILVAWRPPERKFGKFKYYQIIYTNNDGFLPQHWRQFAVKDDNVMLT--HLIASELYHIRVKIVNEIGHGPLSKTISIKTIAGTLSQCPDFKITEIFQSHIKLQWGTPDPVKLFKLIQYNLLCWDV-RLKIVNATAKSSTLFPILNHNLSMNEMEYVLYLKNEKEIKCRLSAINSDGKGMPTEIQASTVNKGVNYQNLIHIDKIGSTYITFQWRPPSKFS 1941
+ +++++T D+ P I + Q V ++ + C+++G+P P I+W + P++ S + IK ++ L I E+D C A N+AG + ++ P F + P+ I P NV + C A G+P P ++W + E T + G +L +D Y C A ++ G+ + + + + S P +P + ++ + ++ I+W SG D +++ Y+ S+ I E + +Y++ L P + Y IW+ + N +G PP+ ++ +T +P +PR++ A +S T ++V W P G + Y++ YT +W++ V DD+++ T L+ E Y +RV +G GPLS I +KT G Q + + ++ I L W P + +I+Y LL + + V T +T + + + LK E RL+A + G G T + + ++ +N + I T + W P ++
Sbjct: 116 ITVHAKLTVLREDQLPSGFPNIDMGPQLKVVERTRTATMLCAASGNPDPEITWFKDFLPVDPSASNGR----------IKQLRSGALQIESSEETDQGKYE-CVATNSAGVRYSSPANLYVRELREVRRVAPRF--SILPMSHEIMP-GGNVNITCVAVGSPMPYVKWMQG----AEDLTPEDDMPVGRNVLELTDVKDSANYTCVAMSSLGV-IEAVAQITVKSLPKAPGTPMVTENTATSITITWDSGNPDPVSY--YVIEYKS----------KSQDGPYQIKEDITTTRYSIGGLSPNSEYEIWVSAVNSIGQGPPSESVVTRTGEQAPASAPRNVQARMLSATTMIVQWEEPVEPNGLIRGYRVYYTMEPEHPVGNWQKHNV-DDSLLTTVGSLLEDETYTVRVLAFTSVGDGPLSDPIQVKTQQGVPGQPMNLRAEARSETSITLSWSPP---RQESIIKYELLFREGDHGREVGRTFDPTTSYVVED-------------LKPNTEYAFRLAARSPQGLGAFTPVVRQRTLQSISPKNF-KVKMIMKTSVLLSWEFPDNYN 634 HSP 4 Score: 109.383 bits (272), Expect = 5.614e-23 Identity = 166/687 (24.16%), Postives = 272/687 (39.59%), Query Frame = 1
Query: 370 LACSSTGHPVPSISW-----KINESPIEELKSPLKKLQNPPRIFSIKNYQNSVLVITQLIESDSNSVLICEAENNAGFDSRQQQLKVISTETDIPSGFPVFQNNFFPIIKPYNSNVTLVCQAYGNPPPLIQWFKNYELINESFT--KIKILNDGNLLLVQVTREDKGIYHCQAQNTNGLRLSDPSTLDITSY----PISPNSLII----ERFASDNVEIS------------WRSGLNDVTEQENFILHYREVPENITEKQIMSKFVYLTISEKKSIYKYNLKDLFPFTTYCIWMESENPLGVSPPTIALTVKTLPTSPQLSPRSITATSISNTAILVAWRPPERKFGKFKYYQIIYTNNDGFLPQHWRQFAVKDDNVMLTHLIAS----ELYHIRVKIVNEIGHGPLSKTISIKTIAGTLSQCP-DFKITEIFQSHIKLQWGTPDPVKLFKLIQYNLLCWDVRLKIVNATAKSSTLFPILN---HNLSMNEMEYVLYLKNEKEIKCRLSAINSDGKG-MPTEIQASTVNKGVNYQNL-IHIDKIGSTYITFQWRPPSKFSFDYFLWIYQIFDSEKLDRAVKLPKIKINISDSASAENGWFVYNYTNAFS-SSRYILGLRYLCRDSTDILREYVHRSDLVSTMKSVPSDSPKDLVVKEIDSNSALVSWKPLDQVHSNGIITHYEVRY 2316
C +TG P P ++W K+N E ++ +VL I L +V C A+N+ G + +L V+ E +PSGFP + T++C A GNP P I WFK++ ++ S + +IK L G L + D+G Y C A N+ G+R S P+ L + ++P I+ E NV I+ W G D+T +++ V N+ E LT ++KD +T C+ M S LGV +TVK+LP +P + T + T+I + W YY I Y + P + +K+D + I Y I V VN IG GP S+++ +T + P + + + + + +QW +PV+ LI+ + + + + P+ N HN+ + + V L ++ R+ A S G G + IQ T +GV Q + + + T IT W PP + S + +++ D + P + D N AF ++R GL T ++R+ T++S+ SPK+ VK I S L+SW+ D +S T Y+++Y
Sbjct: 52 FVCQATGDPKPRVTWNKKGKKVNSQRFETIE--------------FDESAGAVLRIQPLRTPRDENVYECVAQNSVGEITVHAKLTVLR-EDQLPSGFPNIDMGPQLKVVERTRTATMLCAASGNPDPEITWFKDFLPVDPSASNGRIKQLRSGALQIESSEETDQGKYECVATNSAGVRYSSPANLYVRELREVRRVAPRFSILPMSHEIMPGGNVNITCVAVGSPMPYVKWMQGAEDLTPEDDM-----PVGRNVLE---------LT----------DVKDSANYT--CVAMSS---LGVIEAVAQITVKSLPKAPG----TPMVTENTATSITITWD--SGNPDPVSYYVIEYKSKSQDGP-----YQIKEDITTTRYSIGGLSPNSEYEIWVSAVNSIGQGPPSESVVTRTGEQAPASAPRNVQARMLSATTMIVQWE--EPVEPNGLIRGYRVYYTMEPE-----------HPVGNWQKHNVDDSLLTTVGSLLEDETYTVRVLAFTSVGDGPLSDPIQVKT-QQGVPGQPMNLRAEARSETSITLSWSPPRQESIIKYELLFREGDHGREVGRTFDPTTSYVVED--------LKPNTEYAFRLAARSPQGLGAF----TPVVRQ--------RTLQSI---SPKNFKVKMIMKTSVLLSWEFPDNYNSP---TPYKIQY 643 HSP 5 Score: 63.1586 bits (152), Expect = 6.538e-9 Identity = 67/265 (25.28%), Postives = 125/265 (47.17%), Query Frame = 1
Query: 2164 SDLVSTMKSVPSDSPKDLVVKEIDSNSALVSWKPLDQVHSNGIITHYEVRYYAPKKEESTERF----INVSETSAILSNLKYFHYVIYVRAFTKVGGGSWSNPKNYYRQNLEEFP-IPTTIKGERKSETEINISWELPVLSEKNLAHAAIEGFIILYAPVESSPKWIKYTVQSKNLSAVIKGLEPDLRYQFQIAATNYAGFNGNFSEIVQEM------PKNFPNLNLKTVPDLRCSVQSSNRLKVEWSSPSISTDLLKFEIRYSG 2925
S + T + P+ +P+++ + + + + +V W+ + V NG+I Y V YY + E + ++ S + + S L+ Y + V AFT VG G S+P Q + P P ++ E +SET I +SW P +I + +L+ + + + T S V++ L+P+ Y F++AA + G G F+ +V++ PKNF +K + ++ SV S ++SP+ ++I+Y+G
Sbjct: 407 SVVTRTGEQAPASAPRNVQARMLSATTMIVQWE--EPVEPNGLIRGYRV-YYTMEPEHPVGNWQKHNVDDSLLTTVGSLLEDETYTVRVLAFTSVGDGPLSDPIQVKTQ--QGVPGQPMNLRAEARSETSITLSWSPP-------RQESIIKYELLFREGDHG-REVGRTFDPTT-SYVVEDLKPNTEYAFRLAARSPQGL-GAFTPVVRQRTLQSISPKNF---KVKMI--MKTSVLLSWEFPDNYNSPT------PYKIQYNG 645
BLAST of Protein tyrosine phosphatase receptor type D vs. Ensembl Human
Match: PTPRS (protein tyrosine phosphatase receptor type S [Source:HGNC Symbol;Acc:HGNC:9681]) HSP 1 Score: 717.613 bits (1851), Expect = 0.000e+0 Identity = 341/635 (53.70%), Postives = 449/635 (70.71%), Query Frame = 1
Query: 3928 KSIPDLVNADS---VQMCQDGTKLSPVLVSDSIKLRIGSQKSENISDRPSISICNLYQYVTDLKANDCTLLQAEFETLNTNLDDRFTWQRSNIDSNKSKNRYANVVAYDHTSVLLTPVDDVIGSDYINANYIDGYQRQNAYIATQGPLPDTTDDFWRMVWEQRSNCIVMMTRLEERSGIKCHQYWPNRGFICYGQMIVSHIDTFVLAYYTIRLFEIRHSKYSEKREIQHFQFTAWPDHGVPKLSTPLLMFIRRVRSIGKIESCPKIVHCSAGVGRTGAFIVVDAQLERIKQEKNIDVFNYVSKIRCQRNYMVQTQAQYQFILETLLEAVEDGNTEVMACNFHAHVTKLSQIGISGSNQLSGFEMEFSKLNSLASNRGRHGVMLADFVKAAGNQAVNMTKNRVRNIIPYEWNRVVLNAIRGIEGSDYINASYIDGYRDRRAYIAAQSPIPSTVEDFWRMLWDQHCGVVIVLNQPHE---DKSHIYWPINKSIRYQFFVVDPVVEYNMPNYILREFKVTDARDGEFRALRQFQFTQWPNHGCPKESESILDFIRQVHKTKEQFGHMEPMVIHCNTGSGRTGVFIALSIVLDRLQQESVVDMYQTVKLLHKQRIGLVQTEEQYEFCYMAVLDYLSNYE 5814
K+ PD DS + + L+P D +++R + ++ + P I I ++ ++ LKAND L E+E+++ +FTW+ SN++ NK KNRYANV+AYDH+ V+L P++ ++GSDYINANY+DGY+ QNAYIATQGPLP+T DFWRMVWEQRS IVMMTRLEE+S IKC QYWPNRG YG + V+ +DT LA + +R F + + SEKRE++ FQFTAWPDHGVP+ TP L F+RRV++ ++ P +VHCSAGVGRTG FIV+DA LERIK EK +DV+ +V+ +R QRNYMVQT+ QY FI E LLEAV GNTEV A + +A++ KL+Q + ++G E+EF +L + ++ R F+ A N N KNR+ NI+PYE RV L IRG+EGSDYINAS+IDGYR ++AYIA Q P+ T EDFWRMLW+ + +V++L + E +K H YWP +S RYQ+FVVDP+ EYNMP YILREFKVTDARDG+ R +RQFQFT WP G PK E +DFI QVHKTKEQFG P+ +HC+ G GRTGVFI LSIVL+R++ E VVD++QTVK+L QR +VQTE++Y+FCY A L+YL +++
Sbjct: 876 KNKPDSKRKDSEPRTKCLLNNADLAPHHPKDPVEMRRINFQTPGMLSHPPIPIADMAEHTERLKANDSLKLSQEYESIDPG--QQFTWEHSNLEVNKPKNRYANVIAYDHSRVILQPIEGIMGSDYINANYVDGYRCQNAYIATQGPLPETFGDFWRMVWEQRSATIVMMTRLEEKSRIKCDQYWPNRGTETYGFIQVTLLDTIELATFCVRTFSLHKNGSSEKREVRQFQFTAWPDHGVPEYPTPFLAFLRRVKTCNPPDAGPIVVHCSAGVGRTGCFIVIDAMLERIKPEKTVDVYGHVTLMRSQRNYMVQTEDQYSFIHEALLEAVGCGNTEVPARSLYAYIQKLAQ--VEPGEHVTGMELEFKRLANSKAHTSR-------FISA--NLPCNKFKNRLVNIMPYESTRVCLQPIRGVEGSDYINASFIDGYRQQKAYIATQGPLAETTEDFWRMLWENNSTIVVMLTKLREMGREKCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDARDGQSRTVRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKEQFGQDGPISVHCSAGVGRTGVFITLSIVLERMRYEGVVDIFQTVKMLRTQRPAMVQTEDEYQFCYQAALEYLGSFD 1497 HSP 2 Score: 204.912 bits (520), Expect = 4.060e-52 Identity = 105/262 (40.08%), Postives = 151/262 (57.63%), Query Frame = 1
Query: 5092 NQAVNMTKNRVRNIIPYEWNRVVLNAIRGIEGSDYINASYIDGYRDRRAYIAAQSPIPSTVEDFWRMLWDQHCGVVIVLNQPHEDKSHI----YWPINKSIRYQFFVVDPVVEYNMPNYILREFKVTDARDGEFRALRQFQFTQWPNHGCPKESESILDFIRQVHKTKEQFGHMEPMVIHCNTGSGRTGVFIALSIVLDRLQQESVVDMYQTVKLLHKQRIGLVQTEEQYEFCYMAVLDYLSNYEKILEKSHLY*TYQDLSE 5865
N VN KNR N+I Y+ +RV+L I GI GSDYINA+Y+DGYR + AYIA Q P+P T DFWRM+W+Q ++++ + E+KS I YWP + Y F V + + + +R F + E R +RQFQFT WP+HG P+ L F+R+V P+V+HC+ G GRTG FI + +L+R++ E VD+Y V L+ QR +VQTE+QY F + A+L+ + + LY Q L++
Sbjct: 965 NLEVNKPKNRYANVIAYDHSRVILQPIEGIMGSDYINANYVDGYRCQNAYIATQGPLPETFGDFWRMVWEQRSATIVMMTR-LEEKSRIKCDQYWPNRGTETYGFIQVTLLDTIELATFCVRTFSLHKNGSSEKREVRQFQFTAWPDHGVPEYPTPFLAFLRRVKTCNPP--DAGPIVVHCSAGVGRTGCFIVIDAMLERIKPEKTVDVYGHVTLMRSQRNYMVQTEDQYSFIHEALLEAVGCGNTEVPARSLYAYIQKLAQ 1223 HSP 3 Score: 125.561 bits (314), Expect = 6.834e-28 Identity = 128/567 (22.57%), Postives = 238/567 (41.98%), Query Frame = 1
Query: 268 VLINSQITFTENDEAPK----ISLIIQSPNVLLFKSMILACSSTGHPVPSISWKINESPIEELKSPLKKLQNPPRIFSIKNYQNSVLVITQLIESDSNSVLICEAENNAGFDSRQQQLKVISTETDIP--SGFPVFQNNFFPIIKPYNSNVTLVCQAYGNPPPLIQWFKNYELINESFTKIKILNDGNLLLVQVTREDKGIYHCQAQNTNGLRLSDPSTLDITSYPISPNSLIIERFASDNVEISWRSGLNDVTEQENFILHYREVPENITEKQIMSKFVYLTISEKKSIYKYNLKDLFPFTTYCIWMESENPLGVSPPTIALTVKTLPTSPQLSPRSITATSISNTAILVAWRPPERKFGKFKYYQIIYTNNDGFLPQHWRQFAVKDDNVMLT--HLIASELYHIRVKIVNEIGHGPLSKTISIKTIAGTLSQCPDFKITEIFQSHIKLQWGTPDPVKLFKLIQYNLLCWDV-RLKIVNATAKSSTLFPILNHNLSMNEMEYVLYLKNEKEIKCRLSAINSDGKGMPTEIQASTVNKGVNYQNLIHIDKIGSTYITFQWRPPSKFS 1941
+ +++++T D+ P I + Q V ++ + C+++G+P P I+W + P++ S + IK ++ L I E+D C A N+AG + P S P+ I P NV + C A G+P P ++W + E T + G +L +D Y C A ++ G+ + + + + S P +P + ++ + ++ I+W SG D +++ Y+ S+ I E + +Y++ L P + Y IW+ + N +G PP+ ++ +T +P +PR++ A +S T ++V W P G + Y++ YT +W++ V DD+++ T L+ E Y +RV +G GPLS I +KT G Q + + ++ I L W P + +I+Y LL + + V T +T + + + LK E RL+A + G G T + + ++ +N + I T + W P ++
Sbjct: 116 ITVHAKLTVLREDQLPSGFPNIDMGPQLKVVERTRTATMLCAASGNPDPEITWFKDFLPVDPSASNGR----------IKQLRSGALQIESSEETDQGKYE-CVATNSAGVRYSSPANLYVRVRRVAPRFSILPMSHE-----IMP-GGNVNITCVAVGSPMPYVKWMQG----AEDLTPEDDMPVGRNVLELTDVKDSANYTCVAMSSLGV-IEAVAQITVKSLPKAPGTPMVTENTATSITITWDSGNPDPVSY--YVIEYKS----------KSQDGPYQIKEDITTTRYSIGGLSPNSEYEIWVSAVNSIGQGPPSESVVTRTGEQAPASAPRNVQARMLSATTMIVQWEEPVEPNGLIRGYRVYYTMEPEHPVGNWQKHNV-DDSLLTTVGSLLEDETYTVRVLAFTSVGDGPLSDPIQVKTQQGVPGQPMNLRAEARSETSITLSWSPP---RQESIIKYELLFREGDHGREVGRTFDPTTSYVVED-------------LKPNTEYAFRLAARSPQGLGAFTPVVRQRTLQSISPKNF-KVKMIMKTSVLLSWEFPDNYN 630 HSP 4 Score: 114.39 bits (285), Expect = 1.618e-24 Identity = 166/683 (24.30%), Postives = 272/683 (39.82%), Query Frame = 1
Query: 370 LACSSTGHPVPSISW-----KINESPIEELKSPLKKLQNPPRIFSIKNYQNSVLVITQLIESDSNSVLICEAENNAGFDSRQQQLKVISTETDIPSGFPVFQNNFFPIIKPYNSNVTLVCQAYGNPPPLIQWFKNYELINESFT--KIKILNDGNLLLVQVTREDKGIYHCQAQNTNGLRLSDPSTLDITSYPISPNSLII----ERFASDNVEIS------------WRSGLNDVTEQENFILHYREVPENITEKQIMSKFVYLTISEKKSIYKYNLKDLFPFTTYCIWMESENPLGVSPPTIALTVKTLPTSPQLSPRSITATSISNTAILVAWRPPERKFGKFKYYQIIYTNNDGFLPQHWRQFAVKDDNVMLTHLIAS----ELYHIRVKIVNEIGHGPLSKTISIKTIAGTLSQCP-DFKITEIFQSHIKLQWGTPDPVKLFKLIQYNLLCWDVRLKIVNATAKSSTLFPILN---HNLSMNEMEYVLYLKNEKEIKCRLSAINSDGKG-MPTEIQASTVNKGVNYQNL-IHIDKIGSTYITFQWRPPSKFSFDYFLWIYQIFDSEKLDRAVKLPKIKINISDSASAENGWFVYNYTNAFS-SSRYILGLRYLCRDSTDILREYVHRSDLVSTMKSVPSDSPKDLVVKEIDSNSALVSWKPLDQVHSNGIITHYEVRY 2316
C +TG P P ++W K+N E ++ +VL I L +V C A+N+ G + +L V+ E +PSGFP + T++C A GNP P I WFK++ ++ S + +IK L G L + D+G Y C A N+ G+R S P+ L + ++P I+ E NV I+ W G D+T +++ V N+ E LT ++KD +T C+ M S LGV +TVK+LP +P + T + T+I + W YY I Y + P + +K+D + I Y I V VN IG GP S+++ +T + P + + + + + +QW +PV+ LI+ + + + + P+ N HN+ + + V L ++ R+ A S G G + IQ T +GV Q + + + T IT W PP + S + +++ D + P + D N AF ++R GL T ++R+ T++S+ SPK+ VK I S L+SW+ D +S T Y+++Y
Sbjct: 52 FVCQATGDPKPRVTWNKKGKKVNSQRFETIE--------------FDESAGAVLRIQPLRTPRDENVYECVAQNSVGEITVHAKLTVLR-EDQLPSGFPNIDMGPQLKVVERTRTATMLCAASGNPDPEITWFKDFLPVDPSASNGRIKQLRSGALQIESSEETDQGKYECVATNSAGVRYSSPANLYVRVRRVAPRFSILPMSHEIMPGGNVNITCVAVGSPMPYVKWMQGAEDLTPEDDM-----PVGRNVLE---------LT----------DVKDSANYT--CVAMSS---LGVIEAVAQITVKSLPKAPG----TPMVTENTATSITITWD--SGNPDPVSYYVIEYKSKSQDGP-----YQIKEDITTTRYSIGGLSPNSEYEIWVSAVNSIGQGPPSESVVTRTGEQAPASAPRNVQARMLSATTMIVQWE--EPVEPNGLIRGYRVYYTMEPE-----------HPVGNWQKHNVDDSLLTTVGSLLEDETYTVRVLAFTSVGDGPLSDPIQVKT-QQGVPGQPMNLRAEARSETSITLSWSPPRQESIIKYELLFREGDHGREVGRTFDPTTSYVVED--------LKPNTEYAFRLAARSPQGLGAF----TPVVRQ--------RTLQSI---SPKNFKVKMIMKTSVLLSWEFPDNYNSP---TPYKIQY 639 HSP 5 Score: 63.1586 bits (152), Expect = 6.318e-9 Identity = 67/265 (25.28%), Postives = 125/265 (47.17%), Query Frame = 1
Query: 2164 SDLVSTMKSVPSDSPKDLVVKEIDSNSALVSWKPLDQVHSNGIITHYEVRYYAPKKEESTERF----INVSETSAILSNLKYFHYVIYVRAFTKVGGGSWSNPKNYYRQNLEEFP-IPTTIKGERKSETEINISWELPVLSEKNLAHAAIEGFIILYAPVESSPKWIKYTVQSKNLSAVIKGLEPDLRYQFQIAATNYAGFNGNFSEIVQEM------PKNFPNLNLKTVPDLRCSVQSSNRLKVEWSSPSISTDLLKFEIRYSG 2925
S + T + P+ +P+++ + + + + +V W+ + V NG+I Y V YY + E + ++ S + + S L+ Y + V AFT VG G S+P Q + P P ++ E +SET I +SW P +I + +L+ + + + T S V++ L+P+ Y F++AA + G G F+ +V++ PKNF +K + ++ SV S ++SP+ ++I+Y+G
Sbjct: 403 SVVTRTGEQAPASAPRNVQARMLSATTMIVQWE--EPVEPNGLIRGYRV-YYTMEPEHPVGNWQKHNVDDSLLTTVGSLLEDETYTVRVLAFTSVGDGPLSDPIQVKTQ--QGVPGQPMNLRAEARSETSITLSWSPP-------RQESIIKYELLFREGDHG-REVGRTFDPTT-SYVVEDLKPNTEYAFRLAARSPQGL-GAFTPVVRQRTLQSISPKNF---KVKMI--MKTSVLLSWEFPDNYNSPT------PYKIQYNG 641
BLAST of Protein tyrosine phosphatase receptor type D vs. Ensembl Human
Match: PTPRS (protein tyrosine phosphatase receptor type S [Source:HGNC Symbol;Acc:HGNC:9681]) HSP 1 Score: 717.227 bits (1850), Expect = 0.000e+0 Identity = 336/612 (54.90%), Postives = 441/612 (72.06%), Query Frame = 1
Query: 3988 LSPVLVSDSIKLRIGSQKSENISDRPSISICNLYQYVTDLKANDCTLLQAEFETLNTNLDDRFTWQRSNIDSNKSKNRYANVVAYDHTSVLLTPVDDVIGSDYINANYIDGYQRQNAYIATQGPLPDTTDDFWRMVWEQRSNCIVMMTRLEERSGIKCHQYWPNRGFICYGQMIVSHIDTFVLAYYTIRLFEIRHSKYSEKREIQHFQFTAWPDHGVPKLSTPLLMFIRRVRSIGKIESCPKIVHCSAGVGRTGAFIVVDAQLERIKQEKNIDVFNYVSKIRCQRNYMVQTQAQYQFILETLLEAVEDGNTEVMACNFHAHVTKLSQIGISGSNQLSGFEMEFSKLNSLASNRGRHGVMLADFVKAAGNQAVNMTKNRVRNIIPYEWNRVVLNAIRGIEGSDYINASYIDGYRDRRAYIAAQSPIPSTVEDFWRMLWDQHCGVVIVLNQPHE---DKSHIYWPINKSIRYQFFVVDPVVEYNMPNYILREFKVTDARDGEFRALRQFQFTQWPNHGCPKESESILDFIRQVHKTKEQFGHMEPMVIHCNTGSGRTGVFIALSIVLDRLQQESVVDMYQTVKLLHKQRIGLVQTEEQYEFCYMAVLDYLSNYE 5814
L+P D +++R + ++ + P I I ++ ++ LKAND L E+E+++ +FTW+ SN++ NK KNRYANV+AYDH+ V+L P++ ++GSDYINANY+DGY+ QNAYIATQGPLP+T DFWRMVWEQRS IVMMTRLEE+S IKC QYWPNRG YG + V+ +DT LA + +R F + + SEKRE++ FQFTAWPDHGVP+ TP L F+RRV++ ++ P +VHCSAGVGRTG FIV+DA LERIK EK +DV+ +V+ +R QRNYMVQT+ QY FI E LLEAV GNTEV A + +A++ KL+Q + ++G E+EF +L + ++ R F+ A N N KNR+ NI+PYE RV L IRG+EGSDYINAS+IDGYR ++AYIA Q P+ T EDFWRMLW+ + +V++L + E +K H YWP +S RYQ+FVVDP+ EYNMP YILREFKVTDARDG+ R +RQFQFT WP G PK E +DFI QVHKTKEQFG P+ +HC+ G GRTGVFI LSIVL+R++ E VVD++QTVK+L QR +VQTE++Y+FCY A L+YL +++
Sbjct: 899 LAPHHPKDPVEMRRINFQTPGMLSHPPIPIADMAEHTERLKANDSLKLSQEYESIDPG--QQFTWEHSNLEVNKPKNRYANVIAYDHSRVILQPIEGIMGSDYINANYVDGYRCQNAYIATQGPLPETFGDFWRMVWEQRSATIVMMTRLEEKSRIKCDQYWPNRGTETYGFIQVTLLDTIELATFCVRTFSLHKNGSSEKREVRQFQFTAWPDHGVPEYPTPFLAFLRRVKTCNPPDAGPIVVHCSAGVGRTGCFIVIDAMLERIKPEKTVDVYGHVTLMRSQRNYMVQTEDQYSFIHEALLEAVGCGNTEVPARSLYAYIQKLAQ--VEPGEHVTGMELEFKRLANSKAHTSR-------FISA--NLPCNKFKNRLVNIMPYESTRVCLQPIRGVEGSDYINASFIDGYRQQKAYIATQGPLAETTEDFWRMLWENNSTIVVMLTKLREMGREKCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDARDGQSRTVRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKEQFGQDGPISVHCSAGVGRTGVFITLSIVLERMRYEGVVDIFQTVKMLRTQRPAMVQTEDEYQFCYQAALEYLGSFD 1497 HSP 2 Score: 204.527 bits (519), Expect = 4.273e-52 Identity = 105/262 (40.08%), Postives = 151/262 (57.63%), Query Frame = 1
Query: 5092 NQAVNMTKNRVRNIIPYEWNRVVLNAIRGIEGSDYINASYIDGYRDRRAYIAAQSPIPSTVEDFWRMLWDQHCGVVIVLNQPHEDKSHI----YWPINKSIRYQFFVVDPVVEYNMPNYILREFKVTDARDGEFRALRQFQFTQWPNHGCPKESESILDFIRQVHKTKEQFGHMEPMVIHCNTGSGRTGVFIALSIVLDRLQQESVVDMYQTVKLLHKQRIGLVQTEEQYEFCYMAVLDYLSNYEKILEKSHLY*TYQDLSE 5865
N VN KNR N+I Y+ +RV+L I GI GSDYINA+Y+DGYR + AYIA Q P+P T DFWRM+W+Q ++++ + E+KS I YWP + Y F V + + + +R F + E R +RQFQFT WP+HG P+ L F+R+V P+V+HC+ G GRTG FI + +L+R++ E VD+Y V L+ QR +VQTE+QY F + A+L+ + + LY Q L++
Sbjct: 965 NLEVNKPKNRYANVIAYDHSRVILQPIEGIMGSDYINANYVDGYRCQNAYIATQGPLPETFGDFWRMVWEQRSATIVMMTR-LEEKSRIKCDQYWPNRGTETYGFIQVTLLDTIELATFCVRTFSLHKNGSSEKREVRQFQFTAWPDHGVPEYPTPFLAFLRRVKTCNPP--DAGPIVVHCSAGVGRTGCFIVIDAMLERIKPEKTVDVYGHVTLMRSQRNYMVQTEDQYSFIHEALLEAVGCGNTEVPARSLYAYIQKLAQ 1223 HSP 3 Score: 125.561 bits (314), Expect = 7.563e-28 Identity = 128/567 (22.57%), Postives = 238/567 (41.98%), Query Frame = 1
Query: 268 VLINSQITFTENDEAPK----ISLIIQSPNVLLFKSMILACSSTGHPVPSISWKINESPIEELKSPLKKLQNPPRIFSIKNYQNSVLVITQLIESDSNSVLICEAENNAGFDSRQQQLKVISTETDIP--SGFPVFQNNFFPIIKPYNSNVTLVCQAYGNPPPLIQWFKNYELINESFTKIKILNDGNLLLVQVTREDKGIYHCQAQNTNGLRLSDPSTLDITSYPISPNSLIIERFASDNVEISWRSGLNDVTEQENFILHYREVPENITEKQIMSKFVYLTISEKKSIYKYNLKDLFPFTTYCIWMESENPLGVSPPTIALTVKTLPTSPQLSPRSITATSISNTAILVAWRPPERKFGKFKYYQIIYTNNDGFLPQHWRQFAVKDDNVMLT--HLIASELYHIRVKIVNEIGHGPLSKTISIKTIAGTLSQCPDFKITEIFQSHIKLQWGTPDPVKLFKLIQYNLLCWDV-RLKIVNATAKSSTLFPILNHNLSMNEMEYVLYLKNEKEIKCRLSAINSDGKGMPTEIQASTVNKGVNYQNLIHIDKIGSTYITFQWRPPSKFS 1941
+ +++++T D+ P I + Q V ++ + C+++G+P P I+W + P++ S + IK ++ L I E+D C A N+AG + P S P+ I P NV + C A G+P P ++W + E T + G +L +D Y C A ++ G+ + + + + S P +P + ++ + ++ I+W SG D +++ Y+ S+ I E + +Y++ L P + Y IW+ + N +G PP+ ++ +T +P +PR++ A +S T ++V W P G + Y++ YT +W++ V DD+++ T L+ E Y +RV +G GPLS I +KT G Q + + ++ I L W P + +I+Y LL + + V T +T + + + LK E RL+A + G G T + + ++ +N + I T + W P ++
Sbjct: 116 ITVHAKLTVLREDQLPSGFPNIDMGPQLKVVERTRTATMLCAASGNPDPEITWFKDFLPVDPSASNGR----------IKQLRSGALQIESSEETDQGKYE-CVATNSAGVRYSSPANLYVRVRRVAPRFSILPMSHE-----IMP-GGNVNITCVAVGSPMPYVKWMQG----AEDLTPEDDMPVGRNVLELTDVKDSANYTCVAMSSLGV-IEAVAQITVKSLPKAPGTPMVTENTATSITITWDSGNPDPVSY--YVIEYKS----------KSQDGPYQIKEDITTTRYSIGGLSPNSEYEIWVSAVNSIGQGPPSESVVTRTGEQAPASAPRNVQARMLSATTMIVQWEEPVEPNGLIRGYRVYYTMEPEHPVGNWQKHNV-DDSLLTTVGSLLEDETYTVRVLAFTSVGDGPLSDPIQVKTQQGVPGQPMNLRAEARSETSITLSWSPP---RQESIIKYELLFREGDHGREVGRTFDPTTSYVVED-------------LKPNTEYAFRLAARSPQGLGAFTPVVRQRTLQSISPKNF-KVKMIMKTSVLLSWEFPDNYN 630 HSP 4 Score: 114.39 bits (285), Expect = 1.775e-24 Identity = 166/683 (24.30%), Postives = 272/683 (39.82%), Query Frame = 1
Query: 370 LACSSTGHPVPSISW-----KINESPIEELKSPLKKLQNPPRIFSIKNYQNSVLVITQLIESDSNSVLICEAENNAGFDSRQQQLKVISTETDIPSGFPVFQNNFFPIIKPYNSNVTLVCQAYGNPPPLIQWFKNYELINESFT--KIKILNDGNLLLVQVTREDKGIYHCQAQNTNGLRLSDPSTLDITSYPISPNSLII----ERFASDNVEIS------------WRSGLNDVTEQENFILHYREVPENITEKQIMSKFVYLTISEKKSIYKYNLKDLFPFTTYCIWMESENPLGVSPPTIALTVKTLPTSPQLSPRSITATSISNTAILVAWRPPERKFGKFKYYQIIYTNNDGFLPQHWRQFAVKDDNVMLTHLIAS----ELYHIRVKIVNEIGHGPLSKTISIKTIAGTLSQCP-DFKITEIFQSHIKLQWGTPDPVKLFKLIQYNLLCWDVRLKIVNATAKSSTLFPILN---HNLSMNEMEYVLYLKNEKEIKCRLSAINSDGKG-MPTEIQASTVNKGVNYQNL-IHIDKIGSTYITFQWRPPSKFSFDYFLWIYQIFDSEKLDRAVKLPKIKINISDSASAENGWFVYNYTNAFS-SSRYILGLRYLCRDSTDILREYVHRSDLVSTMKSVPSDSPKDLVVKEIDSNSALVSWKPLDQVHSNGIITHYEVRY 2316
C +TG P P ++W K+N E ++ +VL I L +V C A+N+ G + +L V+ E +PSGFP + T++C A GNP P I WFK++ ++ S + +IK L G L + D+G Y C A N+ G+R S P+ L + ++P I+ E NV I+ W G D+T +++ V N+ E LT ++KD +T C+ M S LGV +TVK+LP +P + T + T+I + W YY I Y + P + +K+D + I Y I V VN IG GP S+++ +T + P + + + + + +QW +PV+ LI+ + + + + P+ N HN+ + + V L ++ R+ A S G G + IQ T +GV Q + + + T IT W PP + S + +++ D + P + D N AF ++R GL T ++R+ T++S+ SPK+ VK I S L+SW+ D +S T Y+++Y
Sbjct: 52 FVCQATGDPKPRVTWNKKGKKVNSQRFETIE--------------FDESAGAVLRIQPLRTPRDENVYECVAQNSVGEITVHAKLTVLR-EDQLPSGFPNIDMGPQLKVVERTRTATMLCAASGNPDPEITWFKDFLPVDPSASNGRIKQLRSGALQIESSEETDQGKYECVATNSAGVRYSSPANLYVRVRRVAPRFSILPMSHEIMPGGNVNITCVAVGSPMPYVKWMQGAEDLTPEDDM-----PVGRNVLE---------LT----------DVKDSANYT--CVAMSS---LGVIEAVAQITVKSLPKAPG----TPMVTENTATSITITWD--SGNPDPVSYYVIEYKSKSQDGP-----YQIKEDITTTRYSIGGLSPNSEYEIWVSAVNSIGQGPPSESVVTRTGEQAPASAPRNVQARMLSATTMIVQWE--EPVEPNGLIRGYRVYYTMEPE-----------HPVGNWQKHNVDDSLLTTVGSLLEDETYTVRVLAFTSVGDGPLSDPIQVKT-QQGVPGQPMNLRAEARSETSITLSWSPPRQESIIKYELLFREGDHGREVGRTFDPTTSYVVED--------LKPNTEYAFRLAARSPQGLGAF----TPVVRQ--------RTLQSI---SPKNFKVKMIMKTSVLLSWEFPDNYNSP---TPYKIQY 639 HSP 5 Score: 63.1586 bits (152), Expect = 6.873e-9 Identity = 67/265 (25.28%), Postives = 125/265 (47.17%), Query Frame = 1
Query: 2164 SDLVSTMKSVPSDSPKDLVVKEIDSNSALVSWKPLDQVHSNGIITHYEVRYYAPKKEESTERF----INVSETSAILSNLKYFHYVIYVRAFTKVGGGSWSNPKNYYRQNLEEFP-IPTTIKGERKSETEINISWELPVLSEKNLAHAAIEGFIILYAPVESSPKWIKYTVQSKNLSAVIKGLEPDLRYQFQIAATNYAGFNGNFSEIVQEM------PKNFPNLNLKTVPDLRCSVQSSNRLKVEWSSPSISTDLLKFEIRYSG 2925
S + T + P+ +P+++ + + + + +V W+ + V NG+I Y V YY + E + ++ S + + S L+ Y + V AFT VG G S+P Q + P P ++ E +SET I +SW P +I + +L+ + + + T S V++ L+P+ Y F++AA + G G F+ +V++ PKNF +K + ++ SV S ++SP+ ++I+Y+G
Sbjct: 403 SVVTRTGEQAPASAPRNVQARMLSATTMIVQWE--EPVEPNGLIRGYRV-YYTMEPEHPVGNWQKHNVDDSLLTTVGSLLEDETYTVRVLAFTSVGDGPLSDPIQVKTQ--QGVPGQPMNLRAEARSETSITLSWSPP-------RQESIIKYELLFREGDHG-REVGRTFDPTT-SYVVEDLKPNTEYAFRLAARSPQGL-GAFTPVVRQRTLQSISPKNF---KVKMI--MKTSVLLSWEFPDNYNSPT------PYKIQYNG 641
BLAST of Protein tyrosine phosphatase receptor type D vs. Ensembl Human
Match: PTPRS (protein tyrosine phosphatase receptor type S [Source:HGNC Symbol;Acc:HGNC:9681]) HSP 1 Score: 717.227 bits (1850), Expect = 0.000e+0 Identity = 333/593 (56.16%), Postives = 432/593 (72.85%), Query Frame = 1
Query: 4045 ENISDRPSISICNLYQYVTDLKANDCTLLQAEFETLNTNLDDRFTWQRSNIDSNKSKNRYANVVAYDHTSVLLTPVDDVIGSDYINANYIDGYQRQNAYIATQGPLPDTTDDFWRMVWEQRSNCIVMMTRLEERSGIKCHQYWPNRGFICYGQMIVSHIDTFVLAYYTIRLFEIRHSKYSEKREIQHFQFTAWPDHGVPKLSTPLLMFIRRVRSIGKIESCPKIVHCSAGVGRTGAFIVVDAQLERIKQEKNIDVFNYVSKIRCQRNYMVQTQAQYQFILETLLEAVEDGNTEVMACNFHAHVTKLSQIGISGSNQLSGFEMEFSKLNSLASNRGRHGVMLADFVKAAGNQAVNMTKNRVRNIIPYEWNRVVLNAIRGIEGSDYINASYIDGYRDRRAYIAAQSPIPSTVEDFWRMLWDQHCGVVIVLNQPHE---DKSHIYWPINKSIRYQFFVVDPVVEYNMPNYILREFKVTDARDGEFRALRQFQFTQWPNHGCPKESESILDFIRQVHKTKEQFGHMEPMVIHCNTGSGRTGVFIALSIVLDRLQQESVVDMYQTVKLLHKQRIGLVQTEEQYEFCYMAVLDYLSNYE 5814
E++ P I I ++ ++ LKAND L E+E+++ +FTW+ SN++ NK KNRYANV+AYDH+ V+L P++ ++GSDYINANY+DGY+ QNAYIATQGPLP+T DFWRMVWEQRS IVMMTRLEE+S IKC QYWPNRG YG + V+ +DT LA + +R F + + SEKRE++ FQFTAWPDHGVP+ TP L F+RRV++ ++ P +VHCSAGVGRTG FIV+DA LERIK EK +DV+ +V+ +R QRNYMVQT+ QY FI E LLEAV GNTEV A + +A++ KL+Q + ++G E+EF +L + ++ R F+ A N N KNR+ NI+PYE RV L IRG+EGSDYINAS+IDGYR ++AYIA Q P+ T EDFWRMLW+ + +V++L + E +K H YWP +S RYQ+FVVDP+ EYNMP YILREFKVTDARDG+ R +RQFQFT WP G PK E +DFI QVHKTKEQFG P+ +HC+ G GRTGVFI LSIVL+R++ E VVD++QTVK+L QR +VQTE++Y+FCY A L+YL +++
Sbjct: 1365 ESMLSHPPIPIADMAEHTERLKANDSLKLSQEYESIDPG--QQFTWEHSNLEVNKPKNRYANVIAYDHSRVILQPIEGIMGSDYINANYVDGYRCQNAYIATQGPLPETFGDFWRMVWEQRSATIVMMTRLEEKSRIKCDQYWPNRGTETYGFIQVTLLDTIELATFCVRTFSLHKNGSSEKREVRQFQFTAWPDHGVPEYPTPFLAFLRRVKTCNPPDAGPIVVHCSAGVGRTGCFIVIDAMLERIKPEKTVDVYGHVTLMRSQRNYMVQTEDQYSFIHEALLEAVGCGNTEVPARSLYAYIQKLAQ--VEPGEHVTGMELEFKRLANSKAHTSR-------FISA--NLPCNKFKNRLVNIMPYESTRVCLQPIRGVEGSDYINASFIDGYRQQKAYIATQGPLAETTEDFWRMLWENNSTIVVMLTKLREMGREKCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDARDGQSRTVRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKEQFGQDGPISVHCSAGVGRTGVFITLSIVLERMRYEGVVDIFQTVKMLRTQRPAMVQTEDEYQFCYQAALEYLGSFD 1944 HSP 2 Score: 204.912 bits (520), Expect = 4.867e-52 Identity = 105/262 (40.08%), Postives = 151/262 (57.63%), Query Frame = 1
Query: 5092 NQAVNMTKNRVRNIIPYEWNRVVLNAIRGIEGSDYINASYIDGYRDRRAYIAAQSPIPSTVEDFWRMLWDQHCGVVIVLNQPHEDKSHI----YWPINKSIRYQFFVVDPVVEYNMPNYILREFKVTDARDGEFRALRQFQFTQWPNHGCPKESESILDFIRQVHKTKEQFGHMEPMVIHCNTGSGRTGVFIALSIVLDRLQQESVVDMYQTVKLLHKQRIGLVQTEEQYEFCYMAVLDYLSNYEKILEKSHLY*TYQDLSE 5865
N VN KNR N+I Y+ +RV+L I GI GSDYINA+Y+DGYR + AYIA Q P+P T DFWRM+W+Q ++++ + E+KS I YWP + Y F V + + + +R F + E R +RQFQFT WP+HG P+ L F+R+V P+V+HC+ G GRTG FI + +L+R++ E VD+Y V L+ QR +VQTE+QY F + A+L+ + + LY Q L++
Sbjct: 1412 NLEVNKPKNRYANVIAYDHSRVILQPIEGIMGSDYINANYVDGYRCQNAYIATQGPLPETFGDFWRMVWEQRSATIVMMTR-LEEKSRIKCDQYWPNRGTETYGFIQVTLLDTIELATFCVRTFSLHKNGSSEKREVRQFQFTAWPDHGVPEYPTPFLAFLRRVKTCNPP--DAGPIVVHCSAGVGRTGCFIVIDAMLERIKPEKTVDVYGHVTLMRSQRNYMVQTEDQYSFIHEALLEAVGCGNTEVPARSLYAYIQKLAQ 1670 HSP 3 Score: 147.132 bits (370), Expect = 2.361e-34 Identity = 210/979 (21.45%), Postives = 393/979 (40.14%), Query Frame = 1
Query: 268 VLINSQITFTENDEAPK----ISLIIQSPNVLLFKSMILACSSTGHPVPSISWKINESPIEELKSPLKKLQNPPRIFSIKNYQNSVLVITQLIESDSNSVLICEAENNAGFDSRQQQLKVISTETDIPSGFPVFQNNFFPI---IKPYNSNVTLVCQAYGNPPPLIQWFKNYELINESFTKIKILNDGNLLLVQVTREDKGIYHCQAQNTNGLRLSDPSTLDITSYPISPNSLIIERFASDNVEISWRSGLNDVTEQENFILHYREVPENITEKQIMSKFVYLTISEKKSIYKYNLKDLFPFTTYCIWMESENPLGVSPPTIALTVKTLPTSPQLSPRSITATSISNTAILVAWRPPERKFGKFKYYQIIYTNNDGFLPQHWRQFAVKDDNVMLT--HLIASELYHIRVKIVNEIGHGPLSKTISIKTIAGTLSQCPDFKITEIFQSHIKLQWGTPDPVKLFKLIQYNLLCWDV-RLKIVNATAKSSTLFPILNHNLSMNEMEYVLYLKNEKEIKCRLSAINSDGKGMPTEI--QASTVNKGVNYQNLIHIDKIGSTYITFQWRPPSKFSFDYFLWIYQIFDSEKLDRAVKLPKIKINISDSAS-----AENGWFVYNYTNAFSSSRYILGLRYLCRDSTDILREYVHRSDLVSTMKSVPSDSPKDLVVKEIDSNSALVSWKPLDQVHSNGIITHYEVRYYAPKKEES--TERFINV------------SETSAILSNLK-YFHYVIYVRAFTKVGGGSWSNPKNYYRQN-LEEFPIPTTIKGERKSETEINISWELPVLSEKNLAHAAIEGFIILYAPVESSP-KWIKYTVQSKNLSAVIKGLEPDLRYQFQIAATNYAGFNGNFSEIV---QEMPKNFPNLNLKTVPDLRCSVQSSNRLKVEWSSPSIS---TDLLKF--EIRYSGNLSYITEIGLKKSEFIDMESKSVNFETLVNRYDVTLENLQSNALYKIAVRA 3078
+ +++++T D+ P I + Q V ++ + C+++G+P P I+W + P++ S + Q F + + L I E+D C A N+AG + ++ P F + P+ I P NV + C A G+P P ++W + E T + G +L +D Y C A ++ G+ + + + + S P +P + ++ + ++ I+W SG D +++ Y+ S+ I E + +Y++ L P + Y IW+ + N +G PP+ ++ +T +P +PR++ A +S T ++V W P G + Y++ YT +W++ V DD+++ T L+ E Y +RV +G GPLS I +KT G Q + + ++ I L W P + +I+Y LL + + V T +T + + + LK E RL+A + G G T + Q + +K + + ST I WRPP + + L Y + L PK I + + A W Y T T++ +V T + VPS P+ + + +++ + V W+ +G I Y+V Y + E+ R +V +E +++NL+ Y I V A+T G G+ S PK + + P T+ ++ E + WE P A + G+ + + +S+P +++ +A G+ Y F++AA + G +E++ ++ P+ P + L+ + S+ + + W P + ++K+ +R +G L E L + E+ +TL+ L+ + Y + VRA
Sbjct: 116 ITVHAKLTVLREDQLPSGFPNIDMGPQLKVVERTRTATMLCAASGNPDPEITWFKDFLPVDPSASNGRIKQLRSETFESTPIRGA-LQIESSEETDQGKYE-CVATNSAGVRYSSPANLYVRELREVRRVAPRF--SILPMSHEIMP-GGNVNITCVAVGSPMPYVKWMQG----AEDLTPEDDMPVGRNVLELTDVKDSANYTCVAMSSLGV-IEAVAQITVKSLPKAPGTPMVTENTATSITITWDSGNPDPVSY--YVIEYKS----------KSQDGPYQIKEDITTTRYSIGGLSPNSEYEIWVSAVNSIGQGPPSESVVTRTGEQAPASAPRNVQARMLSATTMIVQWEEPVEPNGLIRGYRVYYTMEPEHPVGNWQKHNV-DDSLLTTVGSLLEDETYTVRVLAFTSVGDGPLSDPIQVKTQQGVPGQPMNLRAEARSETSITLSWSPP---RQESIIKYELLFREGDHGREVGRTFDPTTSYVVED-------------LKPNTEYAFRLAARSPQGLGAFTPVVRQRTLQSKPSAPPQDVKCVSVRSTAILVSWRPPPPETHNGALVGYSV-RYRPLGSEDPEPKEVNGIPPTTTQILLEALEKWTQYRITTV---------------AHTEVGPGPESSPVVVRTDEDVPSAPPRKVEAEALNATAIRVLWRSPAPGRQHGQIRGYQVHYVRMEGAEARGPPRIKDVMLADAQWETDDTAEYEMVITNLQPETAYSITVAAYTMKGDGARSKPKVVVTKGAVLGRP---TLSVQQTPEGSLLARWEPPA----GTAEDQVLGYRLQFGREDSTPLATLEFPPSEDRYTA--SGVHKGATYVFRLAARSRGGLGEEAAEVLSIPEDTPRGHPQI-LEAAGN-----ASAGTVLLRWLPPVPAERNGAIVKYTVAVREAGALGPARETELPAAAEPGAENA------------LTLQGLKPDTAYDLQVRA 1012 HSP 4 Score: 142.124 bits (357), Expect = 6.659e-33 Identity = 224/973 (23.02%), Postives = 376/973 (38.64%), Query Frame = 1
Query: 370 LACSSTGHPVPSISW-----KINESPIEELKSPLKKLQNPPRIFSIKNYQNSVLVITQLIESDSNSVLICEAENNAGFDSRQQQLKVISTETDIPSGFPVFQNNFFPIIKPYNSNVTLVCQAYGNPPPLIQWFKNYELINESFT--KIKILND---------GNLLLVQVTREDKGIYHCQAQNTNGLRLSDPSTLDITSY----PISPNSLII----ERFASDNVEIS------------WRSGLNDVTEQENFILHYREVPENITEKQIMSKFVYLTISEKKSIYKYNLKDLFPFTTYCIWMESENPLGVSPPTIALTVKTLPTSPQLSPRSITATSISNTAILVAWRPPERKFGKFKYYQIIYTNNDGFLPQHWRQFAVKDDNVMLTHLIAS----ELYHIRVKIVNEIGHGPLSKTISIKTIAGTLSQCP-DFKITEIFQSHIKLQWGTPDPVKLFKLIQYNLLCWDVRLKIVNATAKSSTLFPILN---HNLSMNEMEYVLYLKNEKEIKCRLSAINSDGKG-MPTEIQASTVNKGVNYQNL-IHIDKIGSTYITFQWRPPSKFSFDYFLWIYQIFDSEKLDRAVKLPKIKINISDSASAENGWFVYNYTNAFS-SSRYILGLRYLCRDSTDILREYVHRSDLVSTMKSVPSDSPKDLVVKEIDSNSALVSWKPLDQVHSNGIITHYEVRYYAPKKEESTERFIN---VSETSAILSNL-KYFHYVIYVRAFTKVGGGSWSNPKNYYRQNLEEFP--IPTTIKGERKSETEINISWELPVLSEKNLAHAAIEGFIILYAPVESS----PKWIK---------YTVQSKNLSAVIKGLEPDLRYQFQIAATNYAGFNGNFSE----IVQEMPKNFPNLNLKTVPDLRCSVQSSNRLKVEWSSPSISTDLLKFEIRYSGNLSYITEIGLKKSEFIDMESKSVNFETLVNRYDVTLENLQSNALYKIAVRA 3078
C +TG P P ++W K+N E ++ +VL I L +V C A+N+ G + +L V+ E +PSGFP + T++C A GNP P I WFK++ ++ S + +IK L G L + D+G Y C A N+ G+R S P+ L + ++P I+ E NV I+ W G D+T +++ V N+ E LT ++KD +T C+ M S LGV +TVK+LP +P + T + T+I + W YY I Y + P + +K+D + I Y I V VN IG GP S+++ +T + P + + + + + +QW +PV+ LI+ + + + + P+ N HN+ + + V L ++ R+ A S G G + IQ T +GV Q + + + T IT W PP + S + +++ D + P + D N AF ++R GL T ++R+ T++S PS P+D+ + S + LVSW+P NG + Y VRY E+ + +N + T +L L K+ Y I A T+VG G S+P + E+ P P ++ E + T I + W P + H I G+ + Y +E + P IK T + VI L+P+ Y +AA G +G S+ + + P L+++ P+ L W P+ + + L Y + G + S + ++ F +RY + + + ++++A R+
Sbjct: 52 FVCQATGDPKPRVTWNKKGKKVNSQRFETIE--------------FDESAGAVLRIQPLRTPRDENVYECVAQNSVGEITVHAKLTVLR-EDQLPSGFPNIDMGPQLKVVERTRTATMLCAASGNPDPEITWFKDFLPVDPSASNGRIKQLRSETFESTPIRGALQIESSEETDQGKYECVATNSAGVRYSSPANLYVRELREVRRVAPRFSILPMSHEIMPGGNVNITCVAVGSPMPYVKWMQGAEDLTPEDDM-----PVGRNVLE---------LT----------DVKDSANYT--CVAMSS---LGVIEAVAQITVKSLPKAPG----TPMVTENTATSITITWD--SGNPDPVSYYVIEYKSKSQDGP-----YQIKEDITTTRYSIGGLSPNSEYEIWVSAVNSIGQGPPSESVVTRTGEQAPASAPRNVQARMLSATTMIVQWE--EPVEPNGLIRGYRVYYTMEPE-----------HPVGNWQKHNVDDSLLTTVGSLLEDETYTVRVLAFTSVGDGPLSDPIQVKT-QQGVPGQPMNLRAEARSETSITLSWSPPRQESIIKYELLFREGDHGREVGRTFDPTTSYVVED--------LKPNTEYAFRLAARSPQGLGAF----TPVVRQ--------RTLQSKPSAPPQDVKCVSVRSTAILVSWRPPPPETHNGALVGYSVRYRPLGSEDPEPKEVNGIPPTTTQILLEALEKWTQYRITTVAHTEVGPGPESSP--VVVRTDEDVPSAPPRKVEAEALNATAIRVLWRSPAPGRQ---HGQIRGYQVHYVRMEGAEARGPPRIKDVMLADAQWETDDTAEYEMVITNLQPETAYSITVAAYTMKG-DGARSKPKVVVTKGAVLGRPTLSVQQTPE--------GSLLARWEPPAGTAE--------DQVLGYRLQFGREDSTPL----ATLEFPPSEDRYTASGVHKGATYVFRLAARS 909
BLAST of Protein tyrosine phosphatase receptor type D vs. Ensembl Celegans
Match: ptp-3 (Tyrosine-protein phosphatase Lar-like [Source:UniProtKB/Swiss-Prot;Acc:Q9BMN8]) HSP 1 Score: 590.112 bits (1520), Expect = 0.000e+0 Identity = 275/587 (46.85%), Postives = 393/587 (66.95%), Query Frame = 1
Query: 4063 PSISICNLYQYVTDLKANDCTLLQAEFETLNTNLDDRFTWQRSNIDSNKSKNRYANVVAYDHTSVLLTPVDDVIGSDYINANYIDGYQRQNAYIATQGPLPDTTDDFWRMVWEQRSNCIVMMTRLEERSGIKCHQYWPNRGFICYGQMIVSHIDTFVLAYYTIRLFEIRHSKYSEKREIQHFQFTAWPDHGVPKLSTPLLMFIRRVRSIGKIESCPKIVHCSAGVGRTGAFIVVDAQLERIKQEKNIDVFNYVSKIRCQRNYMVQTQAQYQFILETLLEAVEDGNTEVMACNFHAHVTKLSQIGISGSNQLSGFEMEFSKLNSLASNRGRHGVMLADFVKAAGNQAVNMTKNRVRNIIPYEWNRVVLNAIRGIEGSDYINASYIDGYRDRRAYIAAQSPIPSTVEDFWRMLWDQHCGVVIVL---NQPHEDKSHIYWPINKSIRYQFFVVDPVVEYNMPNYILREFKVTDARDGEFRALRQFQFTQWPNHGCPKESESILDFIRQVHKTKEQFGHMEPMVIHCNTGSGRTGVFIALSIVLDRLQQESVVDMYQTVKLLHKQRIGLVQTEEQYEFCYMAVLDYLSNYE 5814
P++ I L ++ L+ N+ Q+EFE++ T FTW+ S+ D NK KNRYANV AYDH+ V+L+ V+ G DYINANY+DGY + +YIATQGPLP+T DFWRMVWE++S IVM+T LEERS +KC QYWP+RG YG + V+ +++ LA+YT+R ++ E REI+H Q+TAWPDHGVP TP L+F++RV+++ ++ P I HCSAG+GRTGAFIV+D LER++ + +D++ V+ +R QR+YMVQT+ QY FI + +L+AV G+TEV A H H+ LSQ ++QLSG +MEF L +L R V N VN KNR+ + +PY+ NRV++ + G +GSDYINAS+IDGY++R AYIA Q+P T DFWR +W+ + ++ +L N+ +++ YWP+ ++ VV+P+ EY+M +Y LREF+++D E R +RQF F +WP+ G P ++ LDF+ QVH T QFG P+ +HC +G+GRT VFIALSI+LDR++ E VVD++ TVKLL +R ++Q EQY F Y+A +YL+ Y+
Sbjct: 892 PAVPIAELANHIERLRMNNNAGFQSEFESIETG--QHFTWEHSSADMNKHKNRYANVAAYDHSRVVLSNVEGYPGMDYINANYVDGYDKPRSYIATQGPLPETFSDFWRMVWEEQSVTIVMLTNLEERSRVKCDQYWPSRGTATYGDIEVTLLESVHLAHYTMRTMRLKMVGEPEVREIKHLQYTAWPDHGVPDHPTPFLIFLKRVKTLNPNDAGPIISHCSAGIGRTGAFIVIDCMLERLRYDNTVDIYGCVTALRAQRSYMVQTEEQYIFIHDAVLDAVNSGSTEVPASRLHQHLHILSQ---PSADQLSGIDMEFRHLTTLKWTSNRCTV---------ANLPVNRPKNRMLSAVPYDSNRVIMRLLPGADGSDYINASWIDGYKERGAYIATQAPTNETAADFWRAIWEHNSPIIAMLVRTNERGQEQCSDYWPLETGVQVGMLVVEPMAEYDMKHYHLREFRISDINTREVRTVRQFHFMEWPDVGKPHTADHFLDFVTQVHNTYAQFGCTGPITVHCCSGAGRTAVFIALSIILDRMRAEHVVDVFTTVKLLRTERQNMIQEPEQYHFLYLAAYEYLAAYD 1464 HSP 2 Score: 186.422 bits (472), Expect = 6.946e-47 Identity = 102/300 (34.00%), Postives = 161/300 (53.67%), Query Frame = 1
Query: 4987 NQLSGFEMEFSKLNSLASNRGRHGVMLADFVKAAGNQAVNMTKNRVRNIIPYEWNRVVLNAIRGIEGSDYINASYIDGYRDRRAYIAAQSPIPSTVEDFWRMLWDQHCGVVIVLNQPHEDKSHI----YWPINKSIRYQFFVVDPVVEYNMPNYILREFKVTDARDGEFRALRQFQFTQWPNHGCPKESESILDFIRQVHKTKEQFGHMEPMVIHCNTGSGRTGVFIALSIVLDRLQQESVVDMYQTVKLLHKQRIGLVQTEEQYEFCYMAVLDYLSNYEKILEKSHLY*TYQDLSESSV 5874
N +GF+ EF + + G+H F + +N KNR N+ Y+ +RVVL+ + G G DYINA+Y+DGY R+YIA Q P+P T DFWRM+W++ +++L E++S + YWP + Y V + ++ +Y +R ++ + E R ++ Q+T WP+HG P L F+++V P++ HC+ G GRTG FI + +L+RL+ ++ VD+Y V L QR +VQTEEQY F + AVLD +++ + S L+ LS+ S
Sbjct: 909 NNNAGFQSEFESIET-----GQH------FTWEHSSADMNKHKNRYANVAAYDHSRVVLSNVEGYPGMDYINANYVDGYDKPRSYIATQGPLPETFSDFWRMVWEEQSVTIVMLTN-LEERSRVKCDQYWPSRGTATYGDIEVTLLESVHLAHYTMRTMRLKMVGEPEVREIKHLQYTAWPDHGVPDHPTPFLIFLKRVKTLNPN--DAGPIISHCSAGIGRTGAFIVIDCMLERLRYDNTVDIYGCVTALRAQRSYMVQTEEQYIFIHDAVLDAVNSGSTEVPASRLHQHLHILSQPSA 1194
BLAST of Protein tyrosine phosphatase receptor type D vs. Ensembl Celegans
Match: ptp-3 (Tyrosine-protein phosphatase Lar-like [Source:UniProtKB/Swiss-Prot;Acc:Q9BMN8]) HSP 1 Score: 588.571 bits (1516), Expect = 0.000e+0 Identity = 275/587 (46.85%), Postives = 393/587 (66.95%), Query Frame = 1
Query: 4063 PSISICNLYQYVTDLKANDCTLLQAEFETLNTNLDDRFTWQRSNIDSNKSKNRYANVVAYDHTSVLLTPVDDVIGSDYINANYIDGYQRQNAYIATQGPLPDTTDDFWRMVWEQRSNCIVMMTRLEERSGIKCHQYWPNRGFICYGQMIVSHIDTFVLAYYTIRLFEIRHSKYSEKREIQHFQFTAWPDHGVPKLSTPLLMFIRRVRSIGKIESCPKIVHCSAGVGRTGAFIVVDAQLERIKQEKNIDVFNYVSKIRCQRNYMVQTQAQYQFILETLLEAVEDGNTEVMACNFHAHVTKLSQIGISGSNQLSGFEMEFSKLNSLASNRGRHGVMLADFVKAAGNQAVNMTKNRVRNIIPYEWNRVVLNAIRGIEGSDYINASYIDGYRDRRAYIAAQSPIPSTVEDFWRMLWDQHCGVVIVL---NQPHEDKSHIYWPINKSIRYQFFVVDPVVEYNMPNYILREFKVTDARDGEFRALRQFQFTQWPNHGCPKESESILDFIRQVHKTKEQFGHMEPMVIHCNTGSGRTGVFIALSIVLDRLQQESVVDMYQTVKLLHKQRIGLVQTEEQYEFCYMAVLDYLSNYE 5814
P++ I L ++ L+ N+ Q+EFE++ T FTW+ S+ D NK KNRYANV AYDH+ V+L+ V+ G DYINANY+DGY + +YIATQGPLP+T DFWRMVWE++S IVM+T LEERS +KC QYWP+RG YG + V+ +++ LA+YT+R ++ E REI+H Q+TAWPDHGVP TP L+F++RV+++ ++ P I HCSAG+GRTGAFIV+D LER++ + +D++ V+ +R QR+YMVQT+ QY FI + +L+AV G+TEV A H H+ LSQ ++QLSG +MEF L +L R V N VN KNR+ + +PY+ NRV++ + G +GSDYINAS+IDGY++R AYIA Q+P T DFWR +W+ + ++ +L N+ +++ YWP+ ++ VV+P+ EY+M +Y LREF+++D E R +RQF F +WP+ G P ++ LDF+ QVH T QFG P+ +HC +G+GRT VFIALSI+LDR++ E VVD++ TVKLL +R ++Q EQY F Y+A +YL+ Y+
Sbjct: 641 PAVPIAELANHIERLRMNNNAGFQSEFESIETG--QHFTWEHSSADMNKHKNRYANVAAYDHSRVVLSNVEGYPGMDYINANYVDGYDKPRSYIATQGPLPETFSDFWRMVWEEQSVTIVMLTNLEERSRVKCDQYWPSRGTATYGDIEVTLLESVHLAHYTMRTMRLKMVGEPEVREIKHLQYTAWPDHGVPDHPTPFLIFLKRVKTLNPNDAGPIISHCSAGIGRTGAFIVIDCMLERLRYDNTVDIYGCVTALRAQRSYMVQTEEQYIFIHDAVLDAVNSGSTEVPASRLHQHLHILSQ---PSADQLSGIDMEFRHLTTLKWTSNRCTV---------ANLPVNRPKNRMLSAVPYDSNRVIMRLLPGADGSDYINASWIDGYKERGAYIATQAPTNETAADFWRAIWEHNSPIIAMLVRTNERGQEQCSDYWPLETGVQVGMLVVEPMAEYDMKHYHLREFRISDINTREVRTVRQFHFMEWPDVGKPHTADHFLDFVTQVHNTYAQFGCTGPITVHCCSGAGRTAVFIALSIILDRMRAEHVVDVFTTVKLLRTERQNMIQEPEQYHFLYLAAYEYLAAYD 1213 HSP 2 Score: 186.037 bits (471), Expect = 5.939e-47 Identity = 102/300 (34.00%), Postives = 161/300 (53.67%), Query Frame = 1
Query: 4987 NQLSGFEMEFSKLNSLASNRGRHGVMLADFVKAAGNQAVNMTKNRVRNIIPYEWNRVVLNAIRGIEGSDYINASYIDGYRDRRAYIAAQSPIPSTVEDFWRMLWDQHCGVVIVLNQPHEDKSHI----YWPINKSIRYQFFVVDPVVEYNMPNYILREFKVTDARDGEFRALRQFQFTQWPNHGCPKESESILDFIRQVHKTKEQFGHMEPMVIHCNTGSGRTGVFIALSIVLDRLQQESVVDMYQTVKLLHKQRIGLVQTEEQYEFCYMAVLDYLSNYEKILEKSHLY*TYQDLSESSV 5874
N +GF+ EF + + G+H F + +N KNR N+ Y+ +RVVL+ + G G DYINA+Y+DGY R+YIA Q P+P T DFWRM+W++ +++L E++S + YWP + Y V + ++ +Y +R ++ + E R ++ Q+T WP+HG P L F+++V P++ HC+ G GRTG FI + +L+RL+ ++ VD+Y V L QR +VQTEEQY F + AVLD +++ + S L+ LS+ S
Sbjct: 658 NNNAGFQSEFESIET-----GQH------FTWEHSSADMNKHKNRYANVAAYDHSRVVLSNVEGYPGMDYINANYVDGYDKPRSYIATQGPLPETFSDFWRMVWEEQSVTIVMLTN-LEERSRVKCDQYWPSRGTATYGDIEVTLLESVHLAHYTMRTMRLKMVGEPEVREIKHLQYTAWPDHGVPDHPTPFLIFLKRVKTLNPN--DAGPIISHCSAGIGRTGAFIVIDCMLERLRYDNTVDIYGCVTALRAQRSYMVQTEEQYIFIHDAVLDAVNSGSTEVPASRLHQHLHILSQPSA 943
BLAST of Protein tyrosine phosphatase receptor type D vs. Ensembl Celegans
Match: ptp-3 (Tyrosine-protein phosphatase Lar-like [Source:UniProtKB/Swiss-Prot;Acc:Q9BMN8]) HSP 1 Score: 588.186 bits (1515), Expect = 0.000e+0 Identity = 275/587 (46.85%), Postives = 393/587 (66.95%), Query Frame = 1
Query: 4063 PSISICNLYQYVTDLKANDCTLLQAEFETLNTNLDDRFTWQRSNIDSNKSKNRYANVVAYDHTSVLLTPVDDVIGSDYINANYIDGYQRQNAYIATQGPLPDTTDDFWRMVWEQRSNCIVMMTRLEERSGIKCHQYWPNRGFICYGQMIVSHIDTFVLAYYTIRLFEIRHSKYSEKREIQHFQFTAWPDHGVPKLSTPLLMFIRRVRSIGKIESCPKIVHCSAGVGRTGAFIVVDAQLERIKQEKNIDVFNYVSKIRCQRNYMVQTQAQYQFILETLLEAVEDGNTEVMACNFHAHVTKLSQIGISGSNQLSGFEMEFSKLNSLASNRGRHGVMLADFVKAAGNQAVNMTKNRVRNIIPYEWNRVVLNAIRGIEGSDYINASYIDGYRDRRAYIAAQSPIPSTVEDFWRMLWDQHCGVVIVL---NQPHEDKSHIYWPINKSIRYQFFVVDPVVEYNMPNYILREFKVTDARDGEFRALRQFQFTQWPNHGCPKESESILDFIRQVHKTKEQFGHMEPMVIHCNTGSGRTGVFIALSIVLDRLQQESVVDMYQTVKLLHKQRIGLVQTEEQYEFCYMAVLDYLSNYE 5814
P++ I L ++ L+ N+ Q+EFE++ T FTW+ S+ D NK KNRYANV AYDH+ V+L+ V+ G DYINANY+DGY + +YIATQGPLP+T DFWRMVWE++S IVM+T LEERS +KC QYWP+RG YG + V+ +++ LA+YT+R ++ E REI+H Q+TAWPDHGVP TP L+F++RV+++ ++ P I HCSAG+GRTGAFIV+D LER++ + +D++ V+ +R QR+YMVQT+ QY FI + +L+AV G+TEV A H H+ LSQ ++QLSG +MEF L +L R V N VN KNR+ + +PY+ NRV++ + G +GSDYINAS+IDGY++R AYIA Q+P T DFWR +W+ + ++ +L N+ +++ YWP+ ++ VV+P+ EY+M +Y LREF+++D E R +RQF F +WP+ G P ++ LDF+ QVH T QFG P+ +HC +G+GRT VFIALSI+LDR++ E VVD++ TVKLL +R ++Q EQY F Y+A +YL+ Y+
Sbjct: 672 PAVPIAELANHIERLRMNNNAGFQSEFESIETG--QHFTWEHSSADMNKHKNRYANVAAYDHSRVVLSNVEGYPGMDYINANYVDGYDKPRSYIATQGPLPETFSDFWRMVWEEQSVTIVMLTNLEERSRVKCDQYWPSRGTATYGDIEVTLLESVHLAHYTMRTMRLKMVGEPEVREIKHLQYTAWPDHGVPDHPTPFLIFLKRVKTLNPNDAGPIISHCSAGIGRTGAFIVIDCMLERLRYDNTVDIYGCVTALRAQRSYMVQTEEQYIFIHDAVLDAVNSGSTEVPASRLHQHLHILSQ---PSADQLSGIDMEFRHLTTLKWTSNRCTV---------ANLPVNRPKNRMLSAVPYDSNRVIMRLLPGADGSDYINASWIDGYKERGAYIATQAPTNETAADFWRAIWEHNSPIIAMLVRTNERGQEQCSDYWPLETGVQVGMLVVEPMAEYDMKHYHLREFRISDINTREVRTVRQFHFMEWPDVGKPHTADHFLDFVTQVHNTYAQFGCTGPITVHCCSGAGRTAVFIALSIILDRMRAEHVVDVFTTVKLLRTERQNMIQEPEQYHFLYLAAYEYLAAYD 1244 HSP 2 Score: 185.652 bits (470), Expect = 8.326e-47 Identity = 102/300 (34.00%), Postives = 161/300 (53.67%), Query Frame = 1
Query: 4987 NQLSGFEMEFSKLNSLASNRGRHGVMLADFVKAAGNQAVNMTKNRVRNIIPYEWNRVVLNAIRGIEGSDYINASYIDGYRDRRAYIAAQSPIPSTVEDFWRMLWDQHCGVVIVLNQPHEDKSHI----YWPINKSIRYQFFVVDPVVEYNMPNYILREFKVTDARDGEFRALRQFQFTQWPNHGCPKESESILDFIRQVHKTKEQFGHMEPMVIHCNTGSGRTGVFIALSIVLDRLQQESVVDMYQTVKLLHKQRIGLVQTEEQYEFCYMAVLDYLSNYEKILEKSHLY*TYQDLSESSV 5874
N +GF+ EF + + G+H F + +N KNR N+ Y+ +RVVL+ + G G DYINA+Y+DGY R+YIA Q P+P T DFWRM+W++ +++L E++S + YWP + Y V + ++ +Y +R ++ + E R ++ Q+T WP+HG P L F+++V P++ HC+ G GRTG FI + +L+RL+ ++ VD+Y V L QR +VQTEEQY F + AVLD +++ + S L+ LS+ S
Sbjct: 689 NNNAGFQSEFESIET-----GQH------FTWEHSSADMNKHKNRYANVAAYDHSRVVLSNVEGYPGMDYINANYVDGYDKPRSYIATQGPLPETFSDFWRMVWEEQSVTIVMLTN-LEERSRVKCDQYWPSRGTATYGDIEVTLLESVHLAHYTMRTMRLKMVGEPEVREIKHLQYTAWPDHGVPDHPTPFLIFLKRVKTLNPN--DAGPIISHCSAGIGRTGAFIVIDCMLERLRYDNTVDIYGCVTALRAQRSYMVQTEEQYIFIHDAVLDAVNSGSTEVPASRLHQHLHILSQPSA 974
BLAST of Protein tyrosine phosphatase receptor type D vs. Ensembl Celegans
Match: ptp-3 (Tyrosine-protein phosphatase Lar-like [Source:UniProtKB/Swiss-Prot;Acc:Q9BMN8]) HSP 1 Score: 587.8 bits (1514), Expect = 0.000e+0 Identity = 275/587 (46.85%), Postives = 393/587 (66.95%), Query Frame = 1
Query: 4063 PSISICNLYQYVTDLKANDCTLLQAEFETLNTNLDDRFTWQRSNIDSNKSKNRYANVVAYDHTSVLLTPVDDVIGSDYINANYIDGYQRQNAYIATQGPLPDTTDDFWRMVWEQRSNCIVMMTRLEERSGIKCHQYWPNRGFICYGQMIVSHIDTFVLAYYTIRLFEIRHSKYSEKREIQHFQFTAWPDHGVPKLSTPLLMFIRRVRSIGKIESCPKIVHCSAGVGRTGAFIVVDAQLERIKQEKNIDVFNYVSKIRCQRNYMVQTQAQYQFILETLLEAVEDGNTEVMACNFHAHVTKLSQIGISGSNQLSGFEMEFSKLNSLASNRGRHGVMLADFVKAAGNQAVNMTKNRVRNIIPYEWNRVVLNAIRGIEGSDYINASYIDGYRDRRAYIAAQSPIPSTVEDFWRMLWDQHCGVVIVL---NQPHEDKSHIYWPINKSIRYQFFVVDPVVEYNMPNYILREFKVTDARDGEFRALRQFQFTQWPNHGCPKESESILDFIRQVHKTKEQFGHMEPMVIHCNTGSGRTGVFIALSIVLDRLQQESVVDMYQTVKLLHKQRIGLVQTEEQYEFCYMAVLDYLSNYE 5814
P++ I L ++ L+ N+ Q+EFE++ T FTW+ S+ D NK KNRYANV AYDH+ V+L+ V+ G DYINANY+DGY + +YIATQGPLP+T DFWRMVWE++S IVM+T LEERS +KC QYWP+RG YG + V+ +++ LA+YT+R ++ E REI+H Q+TAWPDHGVP TP L+F++RV+++ ++ P I HCSAG+GRTGAFIV+D LER++ + +D++ V+ +R QR+YMVQT+ QY FI + +L+AV G+TEV A H H+ LSQ ++QLSG +MEF L +L R V N VN KNR+ + +PY+ NRV++ + G +GSDYINAS+IDGY++R AYIA Q+P T DFWR +W+ + ++ +L N+ +++ YWP+ ++ VV+P+ EY+M +Y LREF+++D E R +RQF F +WP+ G P ++ LDF+ QVH T QFG P+ +HC +G+GRT VFIALSI+LDR++ E VVD++ TVKLL +R ++Q EQY F Y+A +YL+ Y+
Sbjct: 508 PAVPIAELANHIERLRMNNNAGFQSEFESIETG--QHFTWEHSSADMNKHKNRYANVAAYDHSRVVLSNVEGYPGMDYINANYVDGYDKPRSYIATQGPLPETFSDFWRMVWEEQSVTIVMLTNLEERSRVKCDQYWPSRGTATYGDIEVTLLESVHLAHYTMRTMRLKMVGEPEVREIKHLQYTAWPDHGVPDHPTPFLIFLKRVKTLNPNDAGPIISHCSAGIGRTGAFIVIDCMLERLRYDNTVDIYGCVTALRAQRSYMVQTEEQYIFIHDAVLDAVNSGSTEVPASRLHQHLHILSQ---PSADQLSGIDMEFRHLTTLKWTSNRCTV---------ANLPVNRPKNRMLSAVPYDSNRVIMRLLPGADGSDYINASWIDGYKERGAYIATQAPTNETAADFWRAIWEHNSPIIAMLVRTNERGQEQCSDYWPLETGVQVGMLVVEPMAEYDMKHYHLREFRISDINTREVRTVRQFHFMEWPDVGKPHTADHFLDFVTQVHNTYAQFGCTGPITVHCCSGAGRTAVFIALSIILDRMRAEHVVDVFTTVKLLRTERQNMIQEPEQYHFLYLAAYEYLAAYD 1080 HSP 2 Score: 185.652 bits (470), Expect = 5.948e-47 Identity = 102/300 (34.00%), Postives = 161/300 (53.67%), Query Frame = 1
Query: 4987 NQLSGFEMEFSKLNSLASNRGRHGVMLADFVKAAGNQAVNMTKNRVRNIIPYEWNRVVLNAIRGIEGSDYINASYIDGYRDRRAYIAAQSPIPSTVEDFWRMLWDQHCGVVIVLNQPHEDKSHI----YWPINKSIRYQFFVVDPVVEYNMPNYILREFKVTDARDGEFRALRQFQFTQWPNHGCPKESESILDFIRQVHKTKEQFGHMEPMVIHCNTGSGRTGVFIALSIVLDRLQQESVVDMYQTVKLLHKQRIGLVQTEEQYEFCYMAVLDYLSNYEKILEKSHLY*TYQDLSESSV 5874
N +GF+ EF + + G+H F + +N KNR N+ Y+ +RVVL+ + G G DYINA+Y+DGY R+YIA Q P+P T DFWRM+W++ +++L E++S + YWP + Y V + ++ +Y +R ++ + E R ++ Q+T WP+HG P L F+++V P++ HC+ G GRTG FI + +L+RL+ ++ VD+Y V L QR +VQTEEQY F + AVLD +++ + S L+ LS+ S
Sbjct: 525 NNNAGFQSEFESIET-----GQH------FTWEHSSADMNKHKNRYANVAAYDHSRVVLSNVEGYPGMDYINANYVDGYDKPRSYIATQGPLPETFSDFWRMVWEEQSVTIVMLTN-LEERSRVKCDQYWPSRGTATYGDIEVTLLESVHLAHYTMRTMRLKMVGEPEVREIKHLQYTAWPDHGVPDHPTPFLIFLKRVKTLNPN--DAGPIISHCSAGIGRTGAFIVIDCMLERLRYDNTVDIYGCVTALRAQRSYMVQTEEQYIFIHDAVLDAVNSGSTEVPASRLHQHLHILSQPSA 810
BLAST of Protein tyrosine phosphatase receptor type D vs. Ensembl Celegans
Match: ptp-3 (Tyrosine-protein phosphatase Lar-like [Source:UniProtKB/Swiss-Prot;Acc:Q9BMN8]) HSP 1 Score: 590.112 bits (1520), Expect = 1.100e-180 Identity = 275/587 (46.85%), Postives = 393/587 (66.95%), Query Frame = 1
Query: 4063 PSISICNLYQYVTDLKANDCTLLQAEFETLNTNLDDRFTWQRSNIDSNKSKNRYANVVAYDHTSVLLTPVDDVIGSDYINANYIDGYQRQNAYIATQGPLPDTTDDFWRMVWEQRSNCIVMMTRLEERSGIKCHQYWPNRGFICYGQMIVSHIDTFVLAYYTIRLFEIRHSKYSEKREIQHFQFTAWPDHGVPKLSTPLLMFIRRVRSIGKIESCPKIVHCSAGVGRTGAFIVVDAQLERIKQEKNIDVFNYVSKIRCQRNYMVQTQAQYQFILETLLEAVEDGNTEVMACNFHAHVTKLSQIGISGSNQLSGFEMEFSKLNSLASNRGRHGVMLADFVKAAGNQAVNMTKNRVRNIIPYEWNRVVLNAIRGIEGSDYINASYIDGYRDRRAYIAAQSPIPSTVEDFWRMLWDQHCGVVIVL---NQPHEDKSHIYWPINKSIRYQFFVVDPVVEYNMPNYILREFKVTDARDGEFRALRQFQFTQWPNHGCPKESESILDFIRQVHKTKEQFGHMEPMVIHCNTGSGRTGVFIALSIVLDRLQQESVVDMYQTVKLLHKQRIGLVQTEEQYEFCYMAVLDYLSNYE 5814
P++ I L ++ L+ N+ Q+EFE++ T FTW+ S+ D NK KNRYANV AYDH+ V+L+ V+ G DYINANY+DGY + +YIATQGPLP+T DFWRMVWE++S IVM+T LEERS +KC QYWP+RG YG + V+ +++ LA+YT+R ++ E REI+H Q+TAWPDHGVP TP L+F++RV+++ ++ P I HCSAG+GRTGAFIV+D LER++ + +D++ V+ +R QR+YMVQT+ QY FI + +L+AV G+TEV A H H+ LSQ ++QLSG +MEF L +L R V N VN KNR+ + +PY+ NRV++ + G +GSDYINAS+IDGY++R AYIA Q+P T DFWR +W+ + ++ +L N+ +++ YWP+ ++ VV+P+ EY+M +Y LREF+++D E R +RQF F +WP+ G P ++ LDF+ QVH T QFG P+ +HC +G+GRT VFIALSI+LDR++ E VVD++ TVKLL +R ++Q EQY F Y+A +YL+ Y+
Sbjct: 912 PAVPIAELANHIERLRMNNNAGFQSEFESIETG--QHFTWEHSSADMNKHKNRYANVAAYDHSRVVLSNVEGYPGMDYINANYVDGYDKPRSYIATQGPLPETFSDFWRMVWEEQSVTIVMLTNLEERSRVKCDQYWPSRGTATYGDIEVTLLESVHLAHYTMRTMRLKMVGEPEVREIKHLQYTAWPDHGVPDHPTPFLIFLKRVKTLNPNDAGPIISHCSAGIGRTGAFIVIDCMLERLRYDNTVDIYGCVTALRAQRSYMVQTEEQYIFIHDAVLDAVNSGSTEVPASRLHQHLHILSQ---PSADQLSGIDMEFRHLTTLKWTSNRCTV---------ANLPVNRPKNRMLSAVPYDSNRVIMRLLPGADGSDYINASWIDGYKERGAYIATQAPTNETAADFWRAIWEHNSPIIAMLVRTNERGQEQCSDYWPLETGVQVGMLVVEPMAEYDMKHYHLREFRISDINTREVRTVRQFHFMEWPDVGKPHTADHFLDFVTQVHNTYAQFGCTGPITVHCCSGAGRTAVFIALSIILDRMRAEHVVDVFTTVKLLRTERQNMIQEPEQYHFLYLAAYEYLAAYD 1484 HSP 2 Score: 186.422 bits (472), Expect = 6.724e-47 Identity = 102/300 (34.00%), Postives = 161/300 (53.67%), Query Frame = 1
Query: 4987 NQLSGFEMEFSKLNSLASNRGRHGVMLADFVKAAGNQAVNMTKNRVRNIIPYEWNRVVLNAIRGIEGSDYINASYIDGYRDRRAYIAAQSPIPSTVEDFWRMLWDQHCGVVIVLNQPHEDKSHI----YWPINKSIRYQFFVVDPVVEYNMPNYILREFKVTDARDGEFRALRQFQFTQWPNHGCPKESESILDFIRQVHKTKEQFGHMEPMVIHCNTGSGRTGVFIALSIVLDRLQQESVVDMYQTVKLLHKQRIGLVQTEEQYEFCYMAVLDYLSNYEKILEKSHLY*TYQDLSESSV 5874
N +GF+ EF + + G+H F + +N KNR N+ Y+ +RVVL+ + G G DYINA+Y+DGY R+YIA Q P+P T DFWRM+W++ +++L E++S + YWP + Y V + ++ +Y +R ++ + E R ++ Q+T WP+HG P L F+++V P++ HC+ G GRTG FI + +L+RL+ ++ VD+Y V L QR +VQTEEQY F + AVLD +++ + S L+ LS+ S
Sbjct: 929 NNNAGFQSEFESIET-----GQH------FTWEHSSADMNKHKNRYANVAAYDHSRVVLSNVEGYPGMDYINANYVDGYDKPRSYIATQGPLPETFSDFWRMVWEEQSVTIVMLTN-LEERSRVKCDQYWPSRGTATYGDIEVTLLESVHLAHYTMRTMRLKMVGEPEVREIKHLQYTAWPDHGVPDHPTPFLIFLKRVKTLNPN--DAGPIISHCSAGIGRTGAFIVIDCMLERLRYDNTVDIYGCVTALRAQRSYMVQTEEQYIFIHDAVLDAVNSGSTEVPASRLHQHLHILSQPSA 1214
BLAST of Protein tyrosine phosphatase receptor type D vs. Ensembl Fly
Match: Lar (gene:FBgn0000464 transcript:FBtr0112800) HSP 1 Score: 666.381 bits (1718), Expect = 0.000e+0 Identity = 324/630 (51.43%), Postives = 424/630 (67.30%), Query Frame = 1
Query: 3937 PDLVNADSVQMCQD-GTKLSPVLVSDSIKLRIGSQKSENISDRPSISICNLYQYVTDLKANDCTLLQAEFETLNTNLDDRFTWQRSNIDSNKSKNRYANVVAYDHTSVLLTPVDDVIGSDYINANYIDGYQRQNAYIATQGPLPDTTDDFWRMVWEQRSNCIVMMTRLEERSGIKCHQYWPNRGFICYGQMIVSHIDTFVLAYYTIRLFEIRHSKYSEKREIQHFQFTAWPDHGVPKLSTPLLMFIRRVRSIGKIESCPKIVHCSAGVGRTGAFIVVDAQLERIKQEKNIDVFNYVSKIRCQRNYMVQTQAQYQFILETLLEAVEDGNTEVMACNFHAHVTKLSQIGISGSNQLSGFEMEFSKLNSLASNRGRHGVMLADFVKAAGNQAVNMTKNRVRNIIPYEWNRVVLNAIRGIEGSDYINASYIDGYRDRRAYIAAQSPIPSTVEDFWRMLWDQHCGVVIVLNQPHE---DKSHIYWPINKSIRYQFFVVDPVVEYNMPNYILREFKVTDARDGEFRALRQFQFTQWPNHGCPKESESILDFIRQVHKTKEQFGHMEPMVIHCNTGSGRTGVFIALSIVLDRLQQESVVDMYQTVKLLHKQRIGLVQTEEQYEFCYMAVLDYLSNYE 5814
PD M D G +P SD + +R + ++ + P I I ++ LK+ND E+E++ +FTW SN++ NKSKNRYANV AYDH+ V L V+ V+GSDYINANY DGY++ NAY+ATQGPL +T DFWRM WE ++ IVMMTRLEER+ IKC QYWP RG YGQ+ V+ +T LA Y+IR F++ ++++REI+ QFTAWPDHGVP P L F+RR R++ ES P IVHCSAGVGRTG +IV+D+ LER+K EK ID++ +V+ +R QRNYMVQT+ QY FI + +LEA+ G TEV A N H H+ KL + +SG E+EF KL+++ + + FV A N N KNR+ +I+PYE +RV L I GIEGSDY+NAS+IDGYR R AYIAAQ P+ EDFWRMLW+ + +V++L + E +K YWP +S+RYQ++VVDP+ EYNMP Y LREFKVTDARDG R +RQFQF WP G PK E +DFI QVHKTKEQFG P+ +HC+ G GR+GVFI LSIVL+R+Q E V+D++QTV++L QR +VQTE+QY FCY A L+YL +++
Sbjct: 1394 PDQAAVTRPLMAADLGAGPTP---SDPVDMRRLNFQTPGMISHPPIPISEFANHIERLKSNDNQKFSQEYESIEPG--QQFTWDNSNLEHNKSKNRYANVTAYDHSRVQLPAVEGVVGSDYINANYCDGYRKHNAYVATQGPLQETFVDFWRMCWELKTATIVMMTRLEERTRIKCDQYWPTRGTETYGQIFVTITETQELATYSIRTFQLCRQGFNDRREIKQLQFTAWPDHGVPDHPAPFLQFLRRCRALTPPESGPVIVHCSAGVGRTGCYIVIDSMLERMKHEKIIDIYGHVTCLRAQRNYMVQTEDQYIFIHDAILEAIICGVTEVPARNLHTHLQKL--LITEPGETISGMEVEFKKLSNVKMDSSK-------FVTA--NLPCNKHKNRLVHILPYESSRVYLTPIHGIEGSDYVNASFIDGYRYRSAYIAAQGPVQDAAEDFWRMLWEHNSTIVVMLTKLKEMGREKCFQYWPHERSVRYQYYVVDPIAEYNMPQYKLREFKVTDARDGSSRTVRQFQFIDWPEQGVPKSGEGFIDFIGQVHKTKEQFGQDGPITVHCSAGVGRSGVFITLSIVLERMQYEGVLDVFQTVRILRSQRPAMVQTEDQYHFCYRAALEYLGSFD 2007 HSP 2 Score: 166.392 bits (420), Expect = 1.238e-40 Identity = 212/944 (22.46%), Postives = 391/944 (41.42%), Query Frame = 1
Query: 256 ITQLVLINSQITFTENDEAPK-ISLIIQSPNVLLFK---SMILACSSTGHPVPSISWKINESPIEELKSPLKKLQNPPRIFSIKNYQNSVLVITQLIESDSNSVLICEAENNAGFD-SRQQQLKVISTETDIPSGFPVFQNNFFPIIKPYNSNVTLVCQAYGNPPPLIQWFKNYELINESFTKIKILNDGNLLLVQVTREDKGIYHCQAQNTNGLRLSDPSTLDITSYPISPNSLIIERFASDNVEISWR-SGLNDVTEQENFILHYREVPENITEKQIMSKFVYLTISEKKSIYKYNLKDLFPFTTYCIWMESENPLGVSPPTIALTVKTLPTSPQLSPRSITATSISNTAILVAWRPPERKFGKFKYYQIIYTNNDGFLPQHWRQFAVKDDNV-MLTHLIASELYHIRVKIVNEIGHGPLSKTISIKTIAGTLSQCPDFKITEIFQSHIKLQWGTPDPVKLFKLIQYNLLCWDVRLKIVNATAKSSTLFPILNHNLSMNEMEYVLYLKNEKEIKCRLSAINSDGKGM---PTEIQASTVNKGVNYQNLIHIDKIGSTYITFQWRPPSKFSFDYFLWIYQIFDSEKLDRAVKLPKIKINISDSASAE-NGWFVYNYTNAFSSSRYILGLRYLCRDSTDILREYVHRSDLVSTMKSVPSDSPKDLVVKEIDSNSALVSWKPLDQVHSNGIITHYEVRYYAPKKEESTERFINVSETSAILSNLKY--------FHYVIYVRAFTKVGGGSWSNPKNYYRQNLEEFPIPTTIK---GERKSETEINISWELPVLSEKNLAHAAIEGFI---ILYAPVESSPKWIKYTVQSKNLSAVIKGLEPDLRYQFQIAATNYAGFNGNFSEIVQEMPKNFPNLNLKTVPDLRCSVQSSNRLKVEWSSPS-------ISTDLLKFEIRYSGNLSYITEIGLKKSEFIDMESKS 2991
+ V ++ +T E D+ P +I Q P + + ++++ C + G+P P+I W N++ ++ + NP +S+K+ L I E D C AEN+ G + S+ L V +P F ++ SN+ L C A G+P P ++W K +E T + G +L + ++ Y C A +T G ++ S + + S P +P + I + +V + W G D+ + +++ Y+ P+N + + IS ++Y Y ++ L P+T Y ++ + N +G PP+ T T T + +PR++ ++S++ +++ W PPE G+ Y++ YT N W V + + ++ L +Y +RV+ +G GP+S + +K G SQ +F+ T+I ++ + LQW P ++ Y L D + S++ L+ L + + Y+ L+A + G+G P ++ G +N+ I ST I+ W PP + + Y++F E + + +N++ E W Y +S + R ILR T + VP D P+D+ ++S S VSWKP + NGII Y + +A + + + F+N ++ L++ Y I V A T+ G G S + P+ T+ ER+ I + WE P + L + + L + S P+ K K + +G+E Y+F++A +N+ G +I Q P+ P ++ Q+ + L V W P+ I+ ++F + L + L+K+ F ++E +
Sbjct: 99 VGDAVSADATLTIYEGDKTPAGFPVITQGPGTRVIEVGHTVLMTCKAIGNPTPNIYWIKNQTKVD--------MSNP--RYSLKD---GFLQIENSREEDQGKYE-CVAENSMGTEHSKATNLYVKVRR--VPPTFSRPPETISEVM--LGSNLNLSCIAVGSPMPHVKWMKG----SEDLTPENEMPIGRNVLQLINIQESANYTCIAASTLG-QIDSVSVVKVQSLPTAPTDVQISEVTATSVRLEWSYKGPEDL---QYYVIQYK--PKNANQ-------AFSEISGIITMY-YVVRALSPYTEYEFYVIAVNNIGRGPPSAPATCTTGETKMESAPRNVQVRTLSSSTMVITWEPPETPNGQVTGYKVYYTTNSNQPEASWNSQMVDNSELTTVSELTPHAIYTVRVQAYTSMGAGPMSTPVQVKAQQGVPSQPSNFRATDIGETAVTLQWTKPTHSSE-NIVHYELYWNDTYANQAHHKRISNSEAYTLD-GLYPDTLYYIW-----------LAARSQRGEGATTPPIPVRTKQYVPGAPPRNITAI-ATSSTTISLSWLPPPVERSNGRIIYYKVFFVEVGREDDEATTMTLNMTSIVLDELKRWTEYKIWVLAGTS-----VGDGPRSHPIILR----------TQEDVPGD-PQDVKATPLNSTSIHVSWKPPLEKDRNGIIRGYHI--HAQELRDEGKGFLNEPFKFDVVDTLEFNVTGLQPDTKYSIQVAALTRKGDGDRS--AAIVVKTPGGVPVRPTVSLKIMEREPIVSIELEWERPAQTYGELRGYRLRWGVKDQALKEEMLSGPQMTK-----KRFDNLERGVE----YEFRVAGSNHIGIGQETVKIFQ-TPEGTPG---GPPSNITIRFQTPDVLCVTWDPPTREHRNGIITRYDVQFHKKIDHGLGSERNMTLRKAVFTNLEENT 959 HSP 3 Score: 142.124 bits (357), Expect = 3.645e-33 Identity = 206/874 (23.57%), Postives = 347/874 (39.70%), Query Frame = 1
Query: 1051 ENITEKQIMSKFVYLTISEKKSIY---KYNLKDLFPFTTYCIWMESENPLGVSPPTIALTVKTLPTSPQLSPRSITATSISNTAILVAWRPP--ERKFGKFKYYQIIYTNNDGFLPQHWRQFAVKDDNVM-----LTHLIASEL-----YHIRVKIVNEIGHGPLSKTISIKTIAGTLSQCPDFKITEIFQSHIKLQWGTPDPVKLFKLIQ-YNLLCWDVRLK---IVNATAKSSTLFPILNHNLSMNEMEYVLYLKNEKEIKCRLSAINSDGKGMPTEIQASTVNKGVNYQNLIHI---DKIGSTYITFQWRPPSKFSFDYFLWIYQIFDSEKLDRAVKLPKIKINISDSASAENGWFVYNYTNAFSSSRYILGLRYLCRDSTDILREYVHRSDLVSTMKSVPSDSPKDLVVKEIDSNSALVSWKPLDQVHSNGIITHYEVRYYAPKKEESTERFINVSETSAILSNLKY-FHYVIYVRAFTKVGGGSWSNPKNYYRQNLEEFPIPTTIKGERKSETEINISWELPVLSEKNLAHAAIEGFIILY--APVESSPKWIKYTVQSKNLSAVIKGLEPDLRYQFQIAATNYAGFNGNFSE--IVQEMPKNFPNLNLKTVPDLRCSVQSSNRLKVEWSSPSISTDLLKFEIRYSGNLSYITEIGLKKSEFIDMESKSVNFETLVNRYDVTLENLQSNALYKIAVRAIYQNKELYESHRETTCDTMPAVPNLVKPPIIVGLDEEKSKVIIKLHRCSQRNGKISYYFVIVAAFQGNKNQQISFQEDTESYTFMELSVNTRSNNAKGEYIAI---MKDINDIFKVSGKDHSSVLLGDGTHDENHLSVNKKLEKNFNYRCFARVCLKYSNNSLCKSSPWSE 3582
ENI ++ Y + K I Y L L+P T Y IW+ + + G T + V+T P PR+ITA + S+T I ++W PP ER G+ YY++ + + +DD +T ++ EL Y I V +G GP S I ++T D K T + + I + W P +I+ Y++ ++R + +N K F +++ L N V L+ + + +++A+ G G + GV + + + ++ I +W P++ Y +L VK +K + F N Y R + I +E V + T + P P ++ ++ + V+W P + H NGIIT Y+V+++ K + N++ A+ +NL+ Y+ VRA+TK G G +S+ K + P +++ E SE I WE PV S L G+ I Y VE W TV SA + LE +Y IAA G G SE V+ P++ P LN LR S++ + + W SP I + ++I + ++ G +++ + + + + V + T+ L Y + V AI + + T M A +VKP ++ E ++++ L + S+ G IS+Y+++V + +I Q T+ L + YIA + I F + G+ D+ H N+KLE+ YR F R + L SSP+SE
Sbjct: 525 ENIVHYELYWNDTYANQAHHKRISNSEAYTLDGLYPDTLYYIWLAARSQRGEGATTPPIPVRTKQYVPGAPPRNITAIATSSTTISLSWLPPPVERSNGRIIYYKVFFV-----------EVGREDDEATTMTLNMTSIVLDELKRWTEYKIWVLAGTSVGDGPRSHPIILRTQEDVPGDPQDVKATPLNSTSIHVSWKPPLEKDRNGIIRGYHIHAQELRDEGKGFLNEPFK----FDVVD-TLEFN----VTGLQPDTKYSIQVAALTRKGDGDRSAAIVVKTPGGVPVRPTVSLKIMEREPIVSIELEWERPAQ--------TYGELRGYRLRWGVKDQALKEEMLSGPQMTKKRF----DNLERGVEY--EFRVAGSNHIGIGQETV---KIFQTPEGTPGGPPSNITIRFQTPDVLCVTWDPPTREHRNGIITRYDVQFHK-KIDHGLGSERNMTLRKAVFTNLEENTEYIFRVRAYTKQGAGPFSD-KLIVETERDMGRAPMSLQAEATSEQTAEIWWE-PVTSRGKLL-----GYKIFYTMTAVEDLDDWQTKTV-GLTESADLVNLEKFAQYAVAIAARFKNGL-GRLSEKVTVRIKPEDVP-LN------LRAHDVSTHSMTLSW-SPPIRLTPVNYKISFDAMKVFVDSQGFSQTQIV--PKREIILKHYVKTH--TINELSPFTTYNVNVSAIPSDYSYRPPTKITVTTQMAAPQPMVKPDFYGVVNGE--EILVILPQASEEYGPISHYYLVVVPEDKSNLHKIPDQFLTDDL----LPGRNKPERPNAPYIAAKFPQRSIPFTFHL------------GSGDDYHNFTNRKLEREKRYRIFVRAVVDTPQKHLYTSSPFSE 1321 HSP 4 Score: 138.658 bits (348), Expect = 3.862e-32 Identity = 212/892 (23.77%), Postives = 346/892 (38.79%), Query Frame = 1
Query: 376 CSSTGHPVPSISWKINESPIEELKSPLKKLQNPPRIFSIKNYQNSVLVITQLIESDSNSVLICEAENNAGFDSRQQQLKVISTETDIPSGFPVFQNNFFPIIKPYNSNVTLVCQAYGNPPPLIQWFKNYELINESFTKIKILNDGNLLLVQVTREDKGIYHCQAQNTNGLRLSDPSTLDITSYPISPN-----SLIIERFASDNVEIS------------WRSGLNDVTEQENFILHYREVPENITEKQIMSKFVYLTISEKKSIYKYNLKDLFPFTTYCIWMESENPLGVSPPTIALTVKTLPTSPQLSPRSITATSISNTAILVAW--RPPERKFGKFKYYQIIYTNNDGFLPQHWRQFAVKDDNVMLTHLIASEL-----YHIRVKIVNEIGHGPLSKTISIKTIAGTLSQCP-DFKITEIFQSHIKLQWGTPDPVKLFKLIQYNLLCWDVRLKIVNATAKSSTLFPILNHNLSMN-EMEYVLYLKNEKEIKCRLSAINSDGKG-MPTEIQASTVNKGVNYQ--NLIHIDKIGSTYITFQWRPPSKFS---FDYFLWIYQIFDSEKLDRAVKLPKIKINISDSASAENGWFVYNYTNAFSSSRYILGLRYLCRDSTDILREYVHRSDLVSTMKSVPSDSPKDLVVKEIDSNSALVSWKPLDQVHSNGIITHYEVRYYAPKKEESTERFINVSETSAILSNLK-YFHYVIYVRAFTKVGGGSWSNPKNYYRQNLEEFPI-PTTIKGERKSETEINISWELPVLSEKNLAHAAIEGFIILYAPVESSPKW-----IKYTVQSKNLSAVIKGLEPDLRYQFQIAATNYAGFNGNFSEIVQEMPKNF---PNLNLKTVPDLRCSVQSSNRLKVEWSSPSIS-TDLLKFEIRYS 2922
C++ G P PSI W+ N + +S L+ P I S+L I + ++ C AEN G I P+GFPV + V + C+A GNP P I W KN ++ S + L DG L + ED+G Y C A+N+ G S + L + + P I E N+ +S W G D+T PEN E I + L N+++ +T CI + + LG + V++LPT+P + + ++ T++ + W + PE +YY I Y P++ Q + ++ + + L Y V VN IG GP S + T + P + ++ + S + + W P+ ++ Y V T S+ N + N E+ V L R+ A S G G M T +Q +GV Q N D IG T +T QW P+ S Y L+ + ++ + IS+S + Y + + Y + L + + V T + VP P+++ S + +SW P SNG I +Y+V + +E+ + ++ TS +L LK + Y I+V A T VG G S+P Q E+ P P +K + T I++SW+ P+ ++N I G+ I + K K+ V L + GL+PD +Y Q+AA G + IV + P P ++LK + R + S +++EW P+ + +L + +R+
Sbjct: 39 CAARGDPPPSIVWRKNGKKVSGTQSRYTVLEQPGGI--------SILRIEPVRAGRDDAPYECVAENGVGDAVSADATLTIYEGDKTPAGFPVITQGPGTRVIEVGHTVLMTCKAIGNPTPNIYWIKNQTKVDMSNPRYS-LKDGFLQIENSREEDQGKYECVAENSMGTEHSKATNLYVKVRRVPPTFSRPPETISEVMLGSNLNLSCIAVGSPMPHVKWMKGSEDLT------------PEN--EMPIGRNVLQLI----------NIQESANYT--CI---AASTLGQIDSVSVVKVQSLPTAPT----DVQISEVTATSVRLEWSYKGPE----DLQYYVIQYK------PKNANQAFSEISGIITMYYVVRALSPYTEYEFYVIAVNNIGRGPPSAPATCTTGETKMESAPRNVQVRTLSSSTMVITWEPPE-TPNGQVTGYK----------VYYTTNSNQPEASWNSQMVDNSELTTVSELTPHAIYTVRVQAYTSMGAGPMSTPVQVK-AQQGVPSQPSNFRATD-IGETAVTLQWTKPTHSSENIVHYELYWNDTYANQAHHK---------RISNSEA-------YTLDGLYPDTLYYIWLAARSQRGEGATTPPIP----VRTKQYVPGAPPRNITAIATSSTTISLSWLPPPVERSNGRIIYYKVFFVEVGREDDEATTMTLNMTSIVLDELKRWTEYKIWVLAGTSVGDGPRSHPIILRTQ--EDVPGDPQDVKATPLNSTSIHVSWKPPLEKDRN---GIIRGYHIHAQELRDEGKGFLNEPFKFDV-VDTLEFNVTGLQPDTKYSIQVAALTRKGDGDRSAAIVVKTPGGVPVRPTVSLKIME--REPIVS---IELEWERPAQTYGELRGYRLRWG 834 HSP 5 Score: 53.9138 bits (128), Expect = 2.177e-6 Identity = 63/300 (21.00%), Postives = 119/300 (39.67%), Query Frame = 1
Query: 2203 SPKDLVVKEIDSNSALVSWKPLDQVHSNGIITHYEVRYYAPKKEESTE---RFINVSETSAILSNLKYFHYVIYVRAFTKVGGGSWSNPKNYYRQNLEEFPI-PTTIKGERKSETEINISWELPVLSEKNLAHAAIEGFIILYAPVESSPKWIKYTVQSKNLSAVIKGLEPDLRYQFQIAATNYAGFNGNFSEIVQEMPKNFPNLNLKTVPDLRCSVQSSNRLKVEWSSPSISTDLLKFEIRYSGNLSY----ITEIGLKKSEFIDMESKSVNFETLVNRYDVTLENLQSNALYKIAVRA 3078
+P+++ V+ + S++ +++W+P + NG +T Y+V Y + + ++ SE + + + Y + V+A+T +G G S P Q + P P+ + ET + + W P S +N+ H + + YA + S + + + GL PD Y +AA + G I + P + + + SS + + W P + R +G + Y E+G + E M +N + L+ L+ YKI V A
Sbjct: 401 APRNVQVRTLSSSTMVITWEPPET--PNGQVTGYKVYYTTNSNQPEASWNSQMVDNSELTTVSELTPHAIYTVRVQAYTSMGAGPMSTPVQVKAQ--QGVPSQPSNFRATDIGETAVTLQWTKPTHSSENIVHYELY-WNDTYA------NQAHHKRISNSEAYTLDGLYPDTLYYIWLAARSQRGEGATTPPIPVRTKQYVPGAPPRNITAI---ATSSTTISLSWLPPPVE--------RSNGRIIYYKVFFVEVGREDDEATTM---------TLNMTSIVLDELKRWTEYKIWVLA 669
BLAST of Protein tyrosine phosphatase receptor type D vs. Ensembl Fly
Match: Lar (gene:FBgn0000464 transcript:FBtr0331242) HSP 1 Score: 665.996 bits (1717), Expect = 0.000e+0 Identity = 324/630 (51.43%), Postives = 424/630 (67.30%), Query Frame = 1
Query: 3937 PDLVNADSVQMCQD-GTKLSPVLVSDSIKLRIGSQKSENISDRPSISICNLYQYVTDLKANDCTLLQAEFETLNTNLDDRFTWQRSNIDSNKSKNRYANVVAYDHTSVLLTPVDDVIGSDYINANYIDGYQRQNAYIATQGPLPDTTDDFWRMVWEQRSNCIVMMTRLEERSGIKCHQYWPNRGFICYGQMIVSHIDTFVLAYYTIRLFEIRHSKYSEKREIQHFQFTAWPDHGVPKLSTPLLMFIRRVRSIGKIESCPKIVHCSAGVGRTGAFIVVDAQLERIKQEKNIDVFNYVSKIRCQRNYMVQTQAQYQFILETLLEAVEDGNTEVMACNFHAHVTKLSQIGISGSNQLSGFEMEFSKLNSLASNRGRHGVMLADFVKAAGNQAVNMTKNRVRNIIPYEWNRVVLNAIRGIEGSDYINASYIDGYRDRRAYIAAQSPIPSTVEDFWRMLWDQHCGVVIVLNQPHE---DKSHIYWPINKSIRYQFFVVDPVVEYNMPNYILREFKVTDARDGEFRALRQFQFTQWPNHGCPKESESILDFIRQVHKTKEQFGHMEPMVIHCNTGSGRTGVFIALSIVLDRLQQESVVDMYQTVKLLHKQRIGLVQTEEQYEFCYMAVLDYLSNYE 5814
PD M D G +P SD + +R + ++ + P I I ++ LK+ND E+E++ +FTW SN++ NKSKNRYANV AYDH+ V L V+ V+GSDYINANY DGY++ NAY+ATQGPL +T DFWRM WE ++ IVMMTRLEER+ IKC QYWP RG YGQ+ V+ +T LA Y+IR F++ ++++REI+ QFTAWPDHGVP P L F+RR R++ ES P IVHCSAGVGRTG +IV+D+ LER+K EK ID++ +V+ +R QRNYMVQT+ QY FI + +LEA+ G TEV A N H H+ KL + +SG E+EF KL+++ + + FV A N N KNR+ +I+PYE +RV L I GIEGSDY+NAS+IDGYR R AYIAAQ P+ EDFWRMLW+ + +V++L + E +K YWP +S+RYQ++VVDP+ EYNMP Y LREFKVTDARDG R +RQFQF WP G PK E +DFI QVHKTKEQFG P+ +HC+ G GR+GVFI LSIVL+R+Q E V+D++QTV++L QR +VQTE+QY FCY A L+YL +++
Sbjct: 1324 PDQAAVTRPLMAADLGAGPTP---SDPVDMRRLNFQTPGMISHPPIPISEFANHIERLKSNDNQKFSQEYESIEPG--QQFTWDNSNLEHNKSKNRYANVTAYDHSRVQLPAVEGVVGSDYINANYCDGYRKHNAYVATQGPLQETFVDFWRMCWELKTATIVMMTRLEERTRIKCDQYWPTRGTETYGQIFVTITETQELATYSIRTFQLCRQGFNDRREIKQLQFTAWPDHGVPDHPAPFLQFLRRCRALTPPESGPVIVHCSAGVGRTGCYIVIDSMLERMKHEKIIDIYGHVTCLRAQRNYMVQTEDQYIFIHDAILEAIICGVTEVPARNLHTHLQKL--LITEPGETISGMEVEFKKLSNVKMDSSK-------FVTA--NLPCNKHKNRLVHILPYESSRVYLTPIHGIEGSDYVNASFIDGYRYRSAYIAAQGPVQDAAEDFWRMLWEHNSTIVVMLTKLKEMGREKCFQYWPHERSVRYQYYVVDPIAEYNMPQYKLREFKVTDARDGSSRTVRQFQFIDWPEQGVPKSGEGFIDFIGQVHKTKEQFGQDGPITVHCSAGVGRSGVFITLSIVLERMQYEGVLDVFQTVRILRSQRPAMVQTEDQYHFCYRAALEYLGSFD 1937 HSP 2 Score: 139.043 bits (349), Expect = 2.689e-32 Identity = 207/973 (21.27%), Postives = 390/973 (40.08%), Query Frame = 1
Query: 256 ITQLVLINSQITFTENDEAPK-ISLIIQSPNVLLFK---SMILACSSTGHPVPSISWKINESPIEELKSPLKKLQNPPRIFSIKNYQNSVLVITQLIESDSNSVLICEAENNAGFD-SRQQQLKVISTETDIPSGFPVFQNNFFPIIKPYNSNVTLVCQAYGNPPPLIQWFKNYELINESFTKIKILNDGNLLLVQVTREDKGIYHCQAQNTNGLRLSDPSTLDITSYPISPNSLIIERFASDNVEISWR-SGLNDVTEQENFILHYREVPENITEKQIMSKFVYLTISEKKSIYKYNLKDLFPFTTYCIWMESENPLGVSPPTIALTVKTLPTSPQLSPRSITATSISNTAILVAWRPPERKFGKFKYYQIIYTNNDGFLPQHWRQFAVKDDNVM-LTHLIASELYHIRVKIVNEIGHGPLSKTISIKTIAGTLSQCPDFKITEIFQSHIKLQWGTPDPVKLFKLIQYNLLCWDVRLKIVNATAKSSTLFPILNHNLSMNEMEYV-LYLKNEKEIKCRLSAINSDGK----GMPTEIQASTVNKGVNYQNLIHIDKIGSTYITFQWRPPSKFSFDYFLWIYQIFDSEKLDRAVKL--PKIKINISDSASAENGWFVYNYTNAFSSSRYILGLRYLCRDSTDILREYVHRSDLVSTMKSVPSDSPKDLVVKEIDSNSAL-VSWKPLDQVHSNGIITHYEVRYYAPKKEESTERFINVSETSAILSNL-KYFHYVIYVRAFTKVGGGSWSNPKNYYRQNLEEFPIPTTIKGERKSETEIN--------ISWELPVLSEKNLAHAAIEGFIILYAPVESSPKWIKYTVQSKNLS---AVIKGLEPDLRYQFQIAATNYAGFNGNFSE-IVQEMPKNFPNLNLKTVPDLRCSVQSSNRLKVEWSSPSISTDLLKFEIRYSGNLSYITEIGLKKSEFIDMESKSVNFETLVNRYDVTLENLQSNALYKIAVRAIYQN 3090
+ V ++ +T E D+ P +I Q P + + ++++ C + G+P P+I W N++ ++ + NP +S+K+ L I E D C AEN+ G + S+ L V +P F ++ SN+ L C A G+P P ++W K +E T + G +L + ++ Y C A +T G ++ S + + S P +P + I + +V + W G D+ + +++ Y+ P+N + + IS ++Y Y ++ L P+T Y ++ + N +G PP+ T T S +PR++ ++S++ +++ W PPE G+ Y++ YT N W V + + ++ L +Y +RV+ +G GP+S + +K G SQ +F+ T+I ++ + LQW P ++ Y L D + S++ L+ L + + Y+ L ++++ I K G P +++A+ +N ST I W+PP + + + Y I E D K ++ D+ +N T ++Y + + L R + +V T VP L + E + ++ + W+ Q + G + Y +R+ + E T NL + Y V +G G ++ ++ F P G S I ++W+ P +N G I Y V+ K +N++ AV LE + Y F++ A G G FS+ ++ E ++ + L+ S ++ W + LL ++I Y+ +T + + D ++K+V + L NL+ A Y +A+ A ++N
Sbjct: 131 VGDAVSADATLTIYEGDKTPAGFPVITQGPGTRVIEVGHTVLMTCKAIGNPTPNIYWIKNQTKVD--------MSNP--RYSLKD---GFLQIENSREEDQGKYE-CVAENSMGTEHSKATNLYVKVRR--VPPTFSRPPETISEVM--LGSNLNLSCIAVGSPMPHVKWMKG----SEDLTPENEMPIGRNVLQLINIQESANYTCIAASTLG-QIDSVSVVKVQSLPTAPTDVQISEVTATSVRLEWSYKGPEDL---QYYVIQYK--PKNANQ-------AFSEISGIITMY-YVVRALSPYTEYEFYVIAVNNIGRGPPSAPATCTTEMES---APRNVQVRTLSSSTMVITWEPPETPNGQVTGYKVYYTTNSNQPEASWNSQMVDNSELTTVSELTPHAIYTVRVQAYTSMGAGPMSTPVQVKAQQGVPSQPSNFRATDIGETAVTLQWTKPTHSSE-NIVHYELYWNDTYANQAHHKRISNSEAYTLD-GLYPDTLYYIWLAARSQRGEGATTPPIPVRTKQYVPGDPQDVKATPLN---------------STSIHVSWKPPLEKDRNGIIRGYHIHAQELRDEGKGFLNEPFKFDVVDT-------LEFNVTGLQPDTKYSIQVAALTRKGDGDRSAAI----VVKTPGGVPVRPTVSLKIMEREPIVSIELEWERPAQTY--GELRGYRLRWGVKDQALKEEMLSGPQMTKKRFDNLERGVEYEFRVAGSNHIGIG---------QETVKIFQTPEGTPGGPPSNITIRFQTPDVLCVTWDPPTREHRN-------GIITRYD-VQFHKKIDHGLGSERNMTLRKAVFTNLEENTEYIFRVRAYTKQG-AGPFSDKLIVETERDMGRAPM----SLQAEATSEQTAEIWWEPVTSRGKLLGYKIFYT-----MTAV----EDLDDWQTKTVGLTESAD-----LVNLEKFAQYAVAIAARFKN 998 HSP 3 Score: 126.716 bits (317), Expect = 1.458e-28 Identity = 236/1104 (21.38%), Postives = 425/1104 (38.50%), Query Frame = 1
Query: 346 VLLFKSMILACSSTGHPVPSISW-KINESPIEELKSPLKKLQNPPRIFSIKNYQN-SVLVITQLIESDSNSVLICEAENNAGFDSRQQQLKVISTETDIPSGFPVFQNNFFPIIKPYNSNVTLVCQAYGNPPPLIQWFKNYELINESFTKIKILNDGNLLLVQVTRE-----DKGIYHCQAQNTNGLRLSDPSTLDITSYPISPNSLIIERFASDNVEISWRSGLNDVTEQENFILHY---REVPENITEKQIMSKFVYLTISEKKSIYKYNLKDLFPFTTYCIWMESENPLGVSPPTIALTVKTLPTSPQLSPRSITATSISNTAILVAWRPPERKFGKFKYYQIIYTNNDGFLPQHWRQFAVKDDNVMLTHLIASELYHIRVKIVNEIGHGPLSKTISIKTIAGTLSQCPDFKITEIFQSHIKLQWGTPDPVKLFKLIQ-YNLLCWDVRLK---IVNATAKSSTLFPILNHNLSMNEMEYVLYLKNEKEIKCRLSAINSDGKGMPTEIQASTVNKGVNYQNLIHI---DKIGSTYITFQWRPPSKFSFDYFLWIYQIFDSEKLDRAVKLPKIKINISDSASAENGWFVYNYTNAFSSSRYILGLRYLCRDSTDILREYVHRSDLVSTMKSVPSDSPKDLVVKEIDSNSALVSWKPLDQVHSNGIITHYEVRYYAPKKEESTERFINVSETSAILSNLKY-FHYVIYVRAFTKVGGGSWSNPKNYYRQNLEEFPIPTTIKGERKSETEINISWELPVLSEKNLAHAAIEGFIILY--APVESSPKWIKYTVQSKNLSAVIKGLEPDLRYQFQIAATNYAGFNGNFSE--IVQEMPKNFPNLNLKTVPDLRCSVQSSNRLKVEWSSPSISTDLLKFEIRYSGNLSYITEIGLKKSEFIDMESKSVNFETLVNRYDVTLENLQSNALYKIAVRAIYQNKELYESHRETTCDTMPAVPNLVKPPIIVGLDEEKSKVIIKLHRCSQRNGKISYYFVIVAAFQGNKNQQISFQEDTESYTFMELSVNTRSNNAKGEYIAI---MKDINDIFKVSGKDHSSVLLGDGTHDENHLSVNKKLEKNFNYRCFARVCLKYSNNSLCKSSPWSE 3582
V+L ++ L+C + G P+P + W K +E E + P+ + N ++ +I+ N + + + L + DS SV+ ++ A D + ++ S + P + KP N+N ++F++I G + + V R + Y N S P+T T +P ++ + +S + I+W + + ++Y PE Q++ T+SE L P Y + +++ +G P + + VK P P + AT I TA+ + W P +Y++ + ND + Q + + L L LY+I + ++ G G + I ++T D K T + + I + W P +I+ Y++ ++R + +N K F +++ L N V L+ + + +++A+ G G + GV + + + ++ I +W P++ Y +L VK +K + F N Y R + I +E V + T + P P ++ ++ + V+W P + H NGIIT Y+V+++ K + N++ A+ +NL+ Y+ VRA+TK G G +S+ K + P +++ E SE I WE PV S L G+ I Y VE W TV SA + LE +Y IAA G G SE V+ P++ P LN LR S++ + + W SP I + ++I + ++ G +++ + + + + V + T+ L Y + V AI + + T M A +VKP ++ E ++++ L + S+ G IS+Y+++V + +I Q T+ L + YIA + I F + G+ D+ H N+KLE+ YR F R + L SSP+SE
Sbjct: 260 VMLGSNLNLSCIAVGSPMPHVKWMKGSEDLTPENEMPIGR--NVLQLINIQESANYTCIAASTLGQIDSVSVVKVQSLPTAPTDVQISEVTATSVRLEWSYKGPEDLQYYVIQYKPKNAN-------------------------QAFSEI----SGIITMYYVVRALSPYTEYEFYVIAVNNIGRGPPSAPATC-TTEMESAPRNVQVRTLSSSTMVITWEPPETPNGQVTGYKVYYTTNSNQPEASWNSQMVDNSELTTVSE-----------LTPHAIYTVRVQAYTSMGAGPMSTPVQVKAQQGVPS-QPSNFRATDIGETAVTLQWTKPTHSSENIVHYELYW--NDTYANQAHHKRISNSEAYTLDGLYPDTLYYIWLAARSQRGEGATTPPIPVRTKQYVPGDPQDVKATPLNSTSIHVSWKPPLEKDRNGIIRGYHIHAQELRDEGKGFLNEPFK----FDVVD-TLEFN----VTGLQPDTKYSIQVAALTRKGDGDRSAAIVVKTPGGVPVRPTVSLKIMEREPIVSIELEWERPAQ--------TYGELRGYRLRWGVKDQALKEEMLSGPQMTKKRF----DNLERGVEY--EFRVAGSNHIGIGQETV---KIFQTPEGTPGGPPSNITIRFQTPDVLCVTWDPPTREHRNGIITRYDVQFHK-KIDHGLGSERNMTLRKAVFTNLEENTEYIFRVRAYTKQGAGPFSD-KLIVETERDMGRAPMSLQAEATSEQTAEIWWE-PVTSRGKLL-----GYKIFYTMTAVEDLDDWQTKTV-GLTESADLVNLEKFAQYAVAIAARFKNGL-GRLSEKVTVRIKPEDVP-LN------LRAHDVSTHSMTLSW-SPPIRLTPVNYKISFDAMKVFVDSQGFSQTQIV--PKREIILKHYVKTH--TINELSPFTTYNVNVSAIPSDYSYRPPTKITVTTQMAAPQPMVKPDFYGVVNGE--EILVILPQASEEYGPISHYYLVVVPEDKSNLHKIPDQFLTDDL----LPGRNKPERPNAPYIAAKFPQRSIPFTFHL------------GSGDDYHNFTNRKLEREKRYRIFVRAVVDTPQKHLYTSSPFSE 1251 HSP 4 Score: 113.235 bits (282), Expect = 1.800e-24 Identity = 209/925 (22.59%), Postives = 346/925 (37.41%), Query Frame = 1
Query: 376 CSSTGHPVPSISWKINESPIEELKSPLKKLQNPPRIFSIKNYQNSVLVITQLIESDSNSVLICEAENNAGFDSRQQQLKVISTETDIPSGFPVFQNNFFPIIKPYNSNVTLVCQAYGNPPPLIQWFKNYELINESFTKIKILNDGNLLLVQVTREDKGIYHCQAQNTNGLRLSDPSTLDITSYPISPN-----SLIIERFASDNVEIS------------WRSGLNDVTEQENFILHYREVPENITEKQIMSKFVYLTISEKKSIYKYNLKDLFPFTTYCIWMESENPLGVSPPTIALTVKTLPTSPQLSPRSITATSISNTAILVAW--RPPERKFGKFKYYQIIYTNNDGFLPQHWRQFAVKDDNVMLTHLIASEL-----YHIRVKIVNEIGHGPLSKTISIKTIAGTLSQCP-DFKITEIFQSHIKLQWGTPDPVKLFKLIQYNLLCWDVRLKIVNATAKSSTLFPILNHNLSMN-EMEYVLYLKNEKEIKCRLSAINSDGKG-MPTEIQASTVNKGVNYQ--NLIHIDKIGSTYITFQWRPPSKFS---FDYFLWIYQIFDSEKLDRAVKLPKIKINISDSASAENGWFVYNYTNAFSSSRYILGLRYLCRDSTDILREYVHRSDLVSTMKSVPSDSPKDLVVKEIDSNSALVSWKPLDQVHSNGIITHYEVRYYAPKKEESTERFINVSETSAILSNLKY--------FHYVIYVRAFTKVGGGSWSNPKNYYRQNLEEFPIPTTIK---GERKSETEINISWELPVLSEKNLAHAAIEGFI---ILYAPVESSPKWIKYTVQSKNLSAVIKGLEPDLRYQFQIAATNYAGFNGNFSEIVQEMPKNFPNLNLKTVPDLRCSVQSSNRLKVEWSSPS-------ISTDLLKFEIRYSGNLSYITEIGLKKSEFIDMESKS 2991
C++ G P PSI W+ N + +S L+ P I S+L I + ++ C AEN G I P+GFPV + V + C+A GNP P I W KN ++ S + L DG L + ED+G Y C A+N+ G S + L + + P I E N+ +S W G D+T PEN E I + L N+++ +T CI + + LG + V++LPT+P + + ++ T++ + W + PE +YY I Y P++ Q + ++ + + L Y V VN IG GP S + T + P + ++ + S + + W P+ ++ Y V T S+ N + N E+ V L R+ A S G G M T +Q +GV Q N D IG T +T QW P+ S Y L+ + ++ + IS+S + Y + + Y + L + + V T + VP D P+D+ ++S S VSWKP + NGII Y + +A + + + F+N ++ L++ Y I V A T+ G G S + P+ T+ ER+ I + WE P + L + + L + S P+ K K + +G+E Y+F++A +N+ G +I Q P+ P ++ Q+ + L V W P+ I+ ++F + L + L+K+ F ++E +
Sbjct: 71 CAARGDPPPSIVWRKNGKKVSGTQSRYTVLEQPGGI--------SILRIEPVRAGRDDAPYECVAENGVGDAVSADATLTIYEGDKTPAGFPVITQGPGTRVIEVGHTVLMTCKAIGNPTPNIYWIKNQTKVDMSNPRYS-LKDGFLQIENSREEDQGKYECVAENSMGTEHSKATNLYVKVRRVPPTFSRPPETISEVMLGSNLNLSCIAVGSPMPHVKWMKGSEDLT------------PEN--EMPIGRNVLQLI----------NIQESANYT--CI---AASTLGQIDSVSVVKVQSLPTAPT----DVQISEVTATSVRLEWSYKGPE----DLQYYVIQYK------PKNANQAFSEISGIITMYYVVRALSPYTEYEFYVIAVNNIGRGPPSAPATCTT---EMESAPRNVQVRTLSSSTMVITWEPPE-TPNGQVTGYK----------VYYTTNSNQPEASWNSQMVDNSELTTVSELTPHAIYTVRVQAYTSMGAGPMSTPVQVK-AQQGVPSQPSNFRATD-IGETAVTLQWTKPTHSSENIVHYELYWNDTYANQAHHK---------RISNSEA-------YTLDGLYPDTLYYIWLAARSQRGEGATTPPIP----VRTKQYVPGD-PQDVKATPLNSTSIHVSWKPPLEKDRNGIIRGYHI--HAQELRDEGKGFLNEPFKFDVVDTLEFNVTGLQPDTKYSIQVAALTRKGDGDRS--AAIVVKTPGGVPVRPTVSLKIMEREPIVSIELEWERPAQTYGELRGYRLRWGVKDQALKEEMLSGPQMTK-----KRFDNLERGVE----YEFRVAGSNHIGIGQETVKIFQ-TPEGTPG---GPPSNITIRFQTPDVLCVTWDPPTREHRNGIITRYDVQFHKKIDHGLGSERNMTLRKAVFTNLEENT 889
BLAST of Protein tyrosine phosphatase receptor type D vs. Ensembl Fly
Match: Lar (gene:FBgn0000464 transcript:FBtr0331241) HSP 1 Score: 665.996 bits (1717), Expect = 0.000e+0 Identity = 324/630 (51.43%), Postives = 424/630 (67.30%), Query Frame = 1
Query: 3937 PDLVNADSVQMCQD-GTKLSPVLVSDSIKLRIGSQKSENISDRPSISICNLYQYVTDLKANDCTLLQAEFETLNTNLDDRFTWQRSNIDSNKSKNRYANVVAYDHTSVLLTPVDDVIGSDYINANYIDGYQRQNAYIATQGPLPDTTDDFWRMVWEQRSNCIVMMTRLEERSGIKCHQYWPNRGFICYGQMIVSHIDTFVLAYYTIRLFEIRHSKYSEKREIQHFQFTAWPDHGVPKLSTPLLMFIRRVRSIGKIESCPKIVHCSAGVGRTGAFIVVDAQLERIKQEKNIDVFNYVSKIRCQRNYMVQTQAQYQFILETLLEAVEDGNTEVMACNFHAHVTKLSQIGISGSNQLSGFEMEFSKLNSLASNRGRHGVMLADFVKAAGNQAVNMTKNRVRNIIPYEWNRVVLNAIRGIEGSDYINASYIDGYRDRRAYIAAQSPIPSTVEDFWRMLWDQHCGVVIVLNQPHE---DKSHIYWPINKSIRYQFFVVDPVVEYNMPNYILREFKVTDARDGEFRALRQFQFTQWPNHGCPKESESILDFIRQVHKTKEQFGHMEPMVIHCNTGSGRTGVFIALSIVLDRLQQESVVDMYQTVKLLHKQRIGLVQTEEQYEFCYMAVLDYLSNYE 5814
PD M D G +P SD + +R + ++ + P I I ++ LK+ND E+E++ +FTW SN++ NKSKNRYANV AYDH+ V L V+ V+GSDYINANY DGY++ NAY+ATQGPL +T DFWRM WE ++ IVMMTRLEER+ IKC QYWP RG YGQ+ V+ +T LA Y+IR F++ ++++REI+ QFTAWPDHGVP P L F+RR R++ ES P IVHCSAGVGRTG +IV+D+ LER+K EK ID++ +V+ +R QRNYMVQT+ QY FI + +LEA+ G TEV A N H H+ KL + +SG E+EF KL+++ + + FV A N N KNR+ +I+PYE +RV L I GIEGSDY+NAS+IDGYR R AYIAAQ P+ EDFWRMLW+ + +V++L + E +K YWP +S+RYQ++VVDP+ EYNMP Y LREFKVTDARDG R +RQFQF WP G PK E +DFI QVHKTKEQFG P+ +HC+ G GR+GVFI LSIVL+R+Q E V+D++QTV++L QR +VQTE+QY FCY A L+YL +++
Sbjct: 1310 PDQAAVTRPLMAADLGAGPTP---SDPVDMRRLNFQTPGMISHPPIPISEFANHIERLKSNDNQKFSQEYESIEPG--QQFTWDNSNLEHNKSKNRYANVTAYDHSRVQLPAVEGVVGSDYINANYCDGYRKHNAYVATQGPLQETFVDFWRMCWELKTATIVMMTRLEERTRIKCDQYWPTRGTETYGQIFVTITETQELATYSIRTFQLCRQGFNDRREIKQLQFTAWPDHGVPDHPAPFLQFLRRCRALTPPESGPVIVHCSAGVGRTGCYIVIDSMLERMKHEKIIDIYGHVTCLRAQRNYMVQTEDQYIFIHDAILEAIICGVTEVPARNLHTHLQKL--LITEPGETISGMEVEFKKLSNVKMDSSK-------FVTA--NLPCNKHKNRLVHILPYESSRVYLTPIHGIEGSDYVNASFIDGYRYRSAYIAAQGPVQDAAEDFWRMLWEHNSTIVVMLTKLKEMGREKCFQYWPHERSVRYQYYVVDPIAEYNMPQYKLREFKVTDARDGSSRTVRQFQFIDWPEQGVPKSGEGFIDFIGQVHKTKEQFGQDGPITVHCSAGVGRSGVFITLSIVLERMQYEGVLDVFQTVRILRSQRPAMVQTEDQYHFCYRAALEYLGSFD 1923 HSP 2 Score: 139.428 bits (350), Expect = 2.401e-32 Identity = 211/975 (21.64%), Postives = 390/975 (40.00%), Query Frame = 1
Query: 256 ITQLVLINSQITFTENDEAPK-ISLIIQSPNVLLFK---SMILACSSTGHPVPSISWKINESPIEELKSPLKKLQNPPRIFSIKNYQNSVLVITQLIESDSNSVLICEAENNAGFD-SRQQQLKVISTETDIPSGFPVFQNNFFPIIKPYNSNVTLVCQAYGNPPPLIQWFKNYELINESFTKIKILNDGNLLLVQVTREDKGIYHCQAQNTNGLRLSDPSTLDITSYPISPNSLIIERFASDNVEISWR-SGLNDVTEQENFILHYREVPENITEKQIMSKFVYLTISEKKSIYKYNLKDLFPFTTYCIWMESENPLGVSPPTIALTVKTLPTSPQLSPRSITATSISNTAILVAWRPPERKFGKFKYYQIIYTNNDGFLPQHWRQFAVKDDNVMLT---HLIASELYHIRVKIVNEIGHGPLSKTISIKTIAGTLSQCPDFKITEIFQSHIKLQWGTPDPVKLFKLIQYNLLCWDVRLKIVNATAKSSTLFPILNHNLSMNEMEYV-LYLKNEKEIKCRLSAINSDGK----GMPTEIQASTVNKGVNYQNLIHIDKIGSTYITFQWRPPSKFSFDYFLWIYQIFDSEKLDRAVKL--PKIKINISDSASAENGWFVYNYTNAFSSSRYILGLRYLCRDSTDILREYVHRSDLVSTMKSVPSDSPKDLVVKEIDSNSAL-VSWKPLDQVHSNGIITHYEVRYYAPKKEESTERFINVSETSAILSNL-KYFHYVIYVRAFTKVGGGSWSNPKNYYRQNLEEFPIPTTIKGERKSETEIN--------ISWELPVLSEKNLAHAAIEGFIILYAPVESSPKWIKYTVQSKNLS---AVIKGLEPDLRYQFQIAATNYAGFNGNFSE-IVQEMPKNFPNLNLKTVPDLRCSVQSSNRLKVEWSSPSISTDLLKFEIRYSGNLSYITEIGLKKSEFIDMESKSVNFETLVNRYDVTLENLQSNALYKIAVRAIYQN 3090
+ V ++ +T E D+ P +I Q P + + ++++ C + G+P P+I W N++ ++ + NP +S+K+ L I E D C AEN+ G + S+ L V +P F ++ SN+ L C A G+P P ++W K +E T + G +L + ++ Y C A +T G ++ S + + S P +P + I + +V + W G D+ + +++ Y+ P+N + + IS ++Y Y ++ L P+T Y ++ + N +G PP+ T T S +PR++ ++S++ +++ W PPE G+ Y++ YT N W V DN LT L +Y +RV+ +G GP+S + +K G SQ +F+ T+I ++ + LQW P ++ Y L D + S++ L+ L + + Y+ L ++++ I K G P +++A+ +N ST I W+PP + + + Y I E D K ++ D+ +N T ++Y + + L R + +V T VP L + E + ++ + W+ Q + G + Y +R+ + E T NL + Y V +G G ++ ++ F P G S I ++W+ P +N G I Y V+ K +N++ AV LE + Y F++ A G G FS+ ++ E ++ + L+ S ++ W + LL ++I Y+ +T + + D ++K+V + L NL+ A Y +A+ A ++N
Sbjct: 117 VGDAVSADATLTIYEGDKTPAGFPVITQGPGTRVIEVGHTVLMTCKAIGNPTPNIYWIKNQTKVD--------MSNP--RYSLKD---GFLQIENSREEDQGKYE-CVAENSMGTEHSKATNLYVKVRR--VPPTFSRPPETISEVM--LGSNLNLSCIAVGSPMPHVKWMKG----SEDLTPENEMPIGRNVLQLINIQESANYTCIAASTLG-QIDSVSVVKVQSLPTAPTDVQISEVTATSVRLEWSYKGPEDL---QYYVIQYK--PKNANQ-------AFSEISGIITMY-YVVRALSPYTEYEFYVIAVNNIGRGPPSAPATCTTEMES---APRNVQVRTLSSSTMVITWEPPETPNGQVTGYKVYYTTNSNQPEASWNSQMV--DNSELTTVSELTPHAIYTVRVQAYTSMGAGPMSTPVQVKAQQGVPSQPSNFRATDIGETAVTLQWTKPTHSSE-NIVHYELYWNDTYANQAHHKRISNSEAYTLD-GLYPDTLYYIWLAARSQRGEGATTPPIPVRTKQYVPGDPQDVKATPLN---------------STSIHVSWKPPLEKDRNGIIRGYHIHAQELRDEGKGFLNEPFKFDVVDT-------LEFNVTGLQPDTKYSIQVAALTRKGDGDRSAAI----VVKTPGGVPVRPTVSLKIMEREPIVSIELEWERPAQTY--GELRGYRLRWGVKDQALKEEMLSGPQMTKKRFDNLERGVEYEFRVAGSNHIGIG---------QETVKIFQTPEGTPGGPPSNITIRFQTPDVLCVTWDPPTREHRN-------GIITRYD-VQFHKKIDHGLGSERNMTLRKAVFTNLEENTEYIFRVRAYTKQG-AGPFSDKLIVETERDMGRAPM----SLQAEATSEQTAEIWWEPVTSRGKLLGYKIFYT-----MTAV----EDLDDWQTKTVGLTESAD-----LVNLEKFAQYAVAIAARFKN 984 HSP 3 Score: 126.716 bits (317), Expect = 1.430e-28 Identity = 236/1104 (21.38%), Postives = 425/1104 (38.50%), Query Frame = 1
Query: 346 VLLFKSMILACSSTGHPVPSISW-KINESPIEELKSPLKKLQNPPRIFSIKNYQN-SVLVITQLIESDSNSVLICEAENNAGFDSRQQQLKVISTETDIPSGFPVFQNNFFPIIKPYNSNVTLVCQAYGNPPPLIQWFKNYELINESFTKIKILNDGNLLLVQVTRE-----DKGIYHCQAQNTNGLRLSDPSTLDITSYPISPNSLIIERFASDNVEISWRSGLNDVTEQENFILHY---REVPENITEKQIMSKFVYLTISEKKSIYKYNLKDLFPFTTYCIWMESENPLGVSPPTIALTVKTLPTSPQLSPRSITATSISNTAILVAWRPPERKFGKFKYYQIIYTNNDGFLPQHWRQFAVKDDNVMLTHLIASELYHIRVKIVNEIGHGPLSKTISIKTIAGTLSQCPDFKITEIFQSHIKLQWGTPDPVKLFKLIQ-YNLLCWDVRLK---IVNATAKSSTLFPILNHNLSMNEMEYVLYLKNEKEIKCRLSAINSDGKGMPTEIQASTVNKGVNYQNLIHI---DKIGSTYITFQWRPPSKFSFDYFLWIYQIFDSEKLDRAVKLPKIKINISDSASAENGWFVYNYTNAFSSSRYILGLRYLCRDSTDILREYVHRSDLVSTMKSVPSDSPKDLVVKEIDSNSALVSWKPLDQVHSNGIITHYEVRYYAPKKEESTERFINVSETSAILSNLKY-FHYVIYVRAFTKVGGGSWSNPKNYYRQNLEEFPIPTTIKGERKSETEINISWELPVLSEKNLAHAAIEGFIILY--APVESSPKWIKYTVQSKNLSAVIKGLEPDLRYQFQIAATNYAGFNGNFSE--IVQEMPKNFPNLNLKTVPDLRCSVQSSNRLKVEWSSPSISTDLLKFEIRYSGNLSYITEIGLKKSEFIDMESKSVNFETLVNRYDVTLENLQSNALYKIAVRAIYQNKELYESHRETTCDTMPAVPNLVKPPIIVGLDEEKSKVIIKLHRCSQRNGKISYYFVIVAAFQGNKNQQISFQEDTESYTFMELSVNTRSNNAKGEYIAI---MKDINDIFKVSGKDHSSVLLGDGTHDENHLSVNKKLEKNFNYRCFARVCLKYSNNSLCKSSPWSE 3582
V+L ++ L+C + G P+P + W K +E E + P+ + N ++ +I+ N + + + L + DS SV+ ++ A D + ++ S + P + KP N+N ++F++I G + + V R + Y N S P+T T +P ++ + +S + I+W + + ++Y PE Q++ T+SE L P Y + +++ +G P + + VK P P + AT I TA+ + W P +Y++ + ND + Q + + L L LY+I + ++ G G + I ++T D K T + + I + W P +I+ Y++ ++R + +N K F +++ L N V L+ + + +++A+ G G + GV + + + ++ I +W P++ Y +L VK +K + F N Y R + I +E V + T + P P ++ ++ + V+W P + H NGIIT Y+V+++ K + N++ A+ +NL+ Y+ VRA+TK G G +S+ K + P +++ E SE I WE PV S L G+ I Y VE W TV SA + LE +Y IAA G G SE V+ P++ P LN LR S++ + + W SP I + ++I + ++ G +++ + + + + V + T+ L Y + V AI + + T M A +VKP ++ E ++++ L + S+ G IS+Y+++V + +I Q T+ L + YIA + I F + G+ D+ H N+KLE+ YR F R + L SSP+SE
Sbjct: 246 VMLGSNLNLSCIAVGSPMPHVKWMKGSEDLTPENEMPIGR--NVLQLINIQESANYTCIAASTLGQIDSVSVVKVQSLPTAPTDVQISEVTATSVRLEWSYKGPEDLQYYVIQYKPKNAN-------------------------QAFSEI----SGIITMYYVVRALSPYTEYEFYVIAVNNIGRGPPSAPATC-TTEMESAPRNVQVRTLSSSTMVITWEPPETPNGQVTGYKVYYTTNSNQPEASWNSQMVDNSELTTVSE-----------LTPHAIYTVRVQAYTSMGAGPMSTPVQVKAQQGVPS-QPSNFRATDIGETAVTLQWTKPTHSSENIVHYELYW--NDTYANQAHHKRISNSEAYTLDGLYPDTLYYIWLAARSQRGEGATTPPIPVRTKQYVPGDPQDVKATPLNSTSIHVSWKPPLEKDRNGIIRGYHIHAQELRDEGKGFLNEPFK----FDVVD-TLEFN----VTGLQPDTKYSIQVAALTRKGDGDRSAAIVVKTPGGVPVRPTVSLKIMEREPIVSIELEWERPAQ--------TYGELRGYRLRWGVKDQALKEEMLSGPQMTKKRF----DNLERGVEY--EFRVAGSNHIGIGQETV---KIFQTPEGTPGGPPSNITIRFQTPDVLCVTWDPPTREHRNGIITRYDVQFHK-KIDHGLGSERNMTLRKAVFTNLEENTEYIFRVRAYTKQGAGPFSD-KLIVETERDMGRAPMSLQAEATSEQTAEIWWE-PVTSRGKLL-----GYKIFYTMTAVEDLDDWQTKTV-GLTESADLVNLEKFAQYAVAIAARFKNGL-GRLSEKVTVRIKPEDVP-LN------LRAHDVSTHSMTLSW-SPPIRLTPVNYKISFDAMKVFVDSQGFSQTQIV--PKREIILKHYVKTH--TINELSPFTTYNVNVSAIPSDYSYRPPTKITVTTQMAAPQPMVKPDFYGVVNGE--EILVILPQASEEYGPISHYYLVVVPEDKSNLHKIPDQFLTDDL----LPGRNKPERPNAPYIAAKFPQRSIPFTFHL------------GSGDDYHNFTNRKLEREKRYRIFVRAVVDTPQKHLYTSSPFSE 1237 HSP 4 Score: 114.39 bits (285), Expect = 9.149e-25 Identity = 214/954 (22.43%), Postives = 355/954 (37.21%), Query Frame = 1
Query: 289 TFTENDEAPKISLIIQSPNVLLFKSMILACSSTGHPVPSISWKINESPIEELKSPLKKLQNPPRIFSIKNYQNSVLVITQLIESDSNSVLICEAENNAGFDSRQQQLKVISTETDIPSGFPVFQNNFFPIIKPYNSNVTLVCQAYGNPPPLIQWFKNYELINESFTKIKILNDGNLLLVQVTREDKGIYHCQAQNTNGLRLSDPSTLDITSYPISPN-----SLIIERFASDNVEIS------------WRSGLNDVTEQENFILHYREVPENITEKQIMSKFVYLTISEKKSIYKYNLKDLFPFTTYCIWMESENPLGVSPPTIALTVKTLPTSPQLSPRSITATSISNTAILVAW--RPPERKFGKFKYYQIIYTNNDGFLPQHWRQFAVKDDNVMLTHLIASEL-----YHIRVKIVNEIGHGPLSKTISIKTIAGTLSQCP-DFKITEIFQSHIKLQWGTPDPVKLFKLIQYNLLCWDVRLKIVNATAKSSTLFPILNHNLSMN-EMEYVLYLKNEKEIKCRLSAINSDGKG-MPTEIQASTVNKGVNYQ--NLIHIDKIGSTYITFQWRPPSKFS---FDYFLWIYQIFDSEKLDRAVKLPKIKINISDSASAENGWFVYNYTNAFSSSRYILGLRYLCRDSTDILREYVHRSDLVSTMKSVPSDSPKDLVVKEIDSNSALVSWKPLDQVHSNGIITHYEVRYYAPKKEESTERFINVSETSAILSNLKY--------FHYVIYVRAFTKVGGGSWSNPKNYYRQNLEEFPIPTTIK---GERKSETEINISWELPVLSEKNLAHAAIEGFI---ILYAPVESSPKWIKYTVQSKNLSAVIKGLEPDLRYQFQIAATNYAGFNGNFSEIVQEMPKNFPNLNLKTVPDLRCSVQSSNRLKVEWSSPS-------ISTDLLKFEIRYSGNLSYITEIGLKKSEFIDMESKS 2991
T + P+I Q+ V + C++ G P PSI W+ N + +S L+ P I S+L I + ++ C AEN G I P+GFPV + V + C+A GNP P I W KN ++ S + L DG L + ED+G Y C A+N+ G S + L + + P I E N+ +S W G D+T PEN E I + L N+++ +T CI + + LG + V++LPT+P + + ++ T++ + W + PE +YY I Y P++ Q + ++ + + L Y V VN IG GP S + T + P + ++ + S + + W P+ ++ Y V T S+ N + N E+ V L R+ A S G G M T +Q +GV Q N D IG T +T QW P+ S Y L+ + ++ + IS+S + Y + + Y + L + + V T + VP D P+D+ ++S S VSWKP + NGII Y + +A + + + F+N ++ L++ Y I V A T+ G G S + P+ T+ ER+ I + WE P + L + + L + S P+ K K + +G+E Y+F++A +N+ G +I Q P+ P ++ Q+ + L V W P+ I+ ++F + L + L+K+ F ++E +
Sbjct: 28 TIVDAAHPPEIIRKPQNQGVRVGGVASFYCAARGDPPPSIVWRKNGKKVSGTQSRYTVLEQPGGI--------SILRIEPVRAGRDDAPYECVAENGVGDAVSADATLTIYEGDKTPAGFPVITQGPGTRVIEVGHTVLMTCKAIGNPTPNIYWIKNQTKVDMSNPRYS-LKDGFLQIENSREEDQGKYECVAENSMGTEHSKATNLYVKVRRVPPTFSRPPETISEVMLGSNLNLSCIAVGSPMPHVKWMKGSEDLT------------PEN--EMPIGRNVLQLI----------NIQESANYT--CI---AASTLGQIDSVSVVKVQSLPTAPT----DVQISEVTATSVRLEWSYKGPE----DLQYYVIQYK------PKNANQAFSEISGIITMYYVVRALSPYTEYEFYVIAVNNIGRGPPSAPATCTT---EMESAPRNVQVRTLSSSTMVITWEPPE-TPNGQVTGYK----------VYYTTNSNQPEASWNSQMVDNSELTTVSELTPHAIYTVRVQAYTSMGAGPMSTPVQVK-AQQGVPSQPSNFRATD-IGETAVTLQWTKPTHSSENIVHYELYWNDTYANQAHHK---------RISNSEA-------YTLDGLYPDTLYYIWLAARSQRGEGATTPPIP----VRTKQYVPGD-PQDVKATPLNSTSIHVSWKPPLEKDRNGIIRGYHI--HAQELRDEGKGFLNEPFKFDVVDTLEFNVTGLQPDTKYSIQVAALTRKGDGDRS--AAIVVKTPGGVPVRPTVSLKIMEREPIVSIELEWERPAQTYGELRGYRLRWGVKDQALKEEMLSGPQMTK-----KRFDNLERGVE----YEFRVAGSNHIGIGQETVKIFQ-TPEGTPG---GPPSNITIRFQTPDVLCVTWDPPTREHRNGIITRYDVQFHKKIDHGLGSERNMTLRKAVFTNLEENT 875
BLAST of Protein tyrosine phosphatase receptor type D vs. Ensembl Fly
Match: Lar (gene:FBgn0000464 transcript:FBtr0081260) HSP 1 Score: 665.996 bits (1717), Expect = 0.000e+0 Identity = 324/630 (51.43%), Postives = 424/630 (67.30%), Query Frame = 1
Query: 3937 PDLVNADSVQMCQD-GTKLSPVLVSDSIKLRIGSQKSENISDRPSISICNLYQYVTDLKANDCTLLQAEFETLNTNLDDRFTWQRSNIDSNKSKNRYANVVAYDHTSVLLTPVDDVIGSDYINANYIDGYQRQNAYIATQGPLPDTTDDFWRMVWEQRSNCIVMMTRLEERSGIKCHQYWPNRGFICYGQMIVSHIDTFVLAYYTIRLFEIRHSKYSEKREIQHFQFTAWPDHGVPKLSTPLLMFIRRVRSIGKIESCPKIVHCSAGVGRTGAFIVVDAQLERIKQEKNIDVFNYVSKIRCQRNYMVQTQAQYQFILETLLEAVEDGNTEVMACNFHAHVTKLSQIGISGSNQLSGFEMEFSKLNSLASNRGRHGVMLADFVKAAGNQAVNMTKNRVRNIIPYEWNRVVLNAIRGIEGSDYINASYIDGYRDRRAYIAAQSPIPSTVEDFWRMLWDQHCGVVIVLNQPHE---DKSHIYWPINKSIRYQFFVVDPVVEYNMPNYILREFKVTDARDGEFRALRQFQFTQWPNHGCPKESESILDFIRQVHKTKEQFGHMEPMVIHCNTGSGRTGVFIALSIVLDRLQQESVVDMYQTVKLLHKQRIGLVQTEEQYEFCYMAVLDYLSNYE 5814
PD M D G +P SD + +R + ++ + P I I ++ LK+ND E+E++ +FTW SN++ NKSKNRYANV AYDH+ V L V+ V+GSDYINANY DGY++ NAY+ATQGPL +T DFWRM WE ++ IVMMTRLEER+ IKC QYWP RG YGQ+ V+ +T LA Y+IR F++ ++++REI+ QFTAWPDHGVP P L F+RR R++ ES P IVHCSAGVGRTG +IV+D+ LER+K EK ID++ +V+ +R QRNYMVQT+ QY FI + +LEA+ G TEV A N H H+ KL + +SG E+EF KL+++ + + FV A N N KNR+ +I+PYE +RV L I GIEGSDY+NAS+IDGYR R AYIAAQ P+ EDFWRMLW+ + +V++L + E +K YWP +S+RYQ++VVDP+ EYNMP Y LREFKVTDARDG R +RQFQF WP G PK E +DFI QVHKTKEQFG P+ +HC+ G GR+GVFI LSIVL+R+Q E V+D++QTV++L QR +VQTE+QY FCY A L+YL +++
Sbjct: 1412 PDQAAVTRPLMAADLGAGPTP---SDPVDMRRLNFQTPGMISHPPIPISEFANHIERLKSNDNQKFSQEYESIEPG--QQFTWDNSNLEHNKSKNRYANVTAYDHSRVQLPAVEGVVGSDYINANYCDGYRKHNAYVATQGPLQETFVDFWRMCWELKTATIVMMTRLEERTRIKCDQYWPTRGTETYGQIFVTITETQELATYSIRTFQLCRQGFNDRREIKQLQFTAWPDHGVPDHPAPFLQFLRRCRALTPPESGPVIVHCSAGVGRTGCYIVIDSMLERMKHEKIIDIYGHVTCLRAQRNYMVQTEDQYIFIHDAILEAIICGVTEVPARNLHTHLQKL--LITEPGETISGMEVEFKKLSNVKMDSSK-------FVTA--NLPCNKHKNRLVHILPYESSRVYLTPIHGIEGSDYVNASFIDGYRYRSAYIAAQGPVQDAAEDFWRMLWEHNSTIVVMLTKLKEMGREKCFQYWPHERSVRYQYYVVDPIAEYNMPQYKLREFKVTDARDGSSRTVRQFQFIDWPEQGVPKSGEGFIDFIGQVHKTKEQFGQDGPITVHCSAGVGRSGVFITLSIVLERMQYEGVLDVFQTVRILRSQRPAMVQTEDQYHFCYRAALEYLGSFD 2025 HSP 2 Score: 165.622 bits (418), Expect = 2.209e-40 Identity = 214/945 (22.65%), Postives = 389/945 (41.16%), Query Frame = 1
Query: 256 ITQLVLINSQITFTENDEAPK-ISLIIQSPNVLLFK---SMILACSSTGHPVPSISWKINESPIEELKSPLKKLQNPPRIFSIKNYQNSVLVITQLIESDSNSVLICEAENNAGFD-SRQQQLKVISTETDIPSGFPVFQNNFFPIIKPYNSNVTLVCQAYGNPPPLIQWFKNYELINESFTKIKILNDGNLLLVQVTREDKGIYHCQAQNTNGLRLSDPSTLDITSYPISPNSLIIERFASDNVEISWR-SGLNDVTEQENFILHYREVPENITEKQIMSKFVYLTISEKKSIYKYNLKDLFPFTTYCIWMESENPLGVSPPTIALTVKTLPTSPQLSPRSITATSISNTAILVAWRPPERKFGKFKYYQIIYTNNDGFLPQHWRQFAVKDDNV-MLTHLIASELYHIRVKIVNEIGHGPLSKTISIKTIAGTLSQCPDFKITEIFQSHIKLQWGTPDPVKLFKLIQYNLLCWDVRLKIVNATAKSSTLFPILNHNLSMNEMEYVL-YLKNEKEIKCRLSAINSDGKGM---PTEIQASTVNKGVNYQNLIHIDKIGSTYITFQWRPPSKFSFDYFLWIYQIFDSEKLDRAVKLPKIKINISDSASAE-NGWFVYNYTNAFSSSRYILGLRYLCRDSTDILREYVHRSDLVSTMKSVPSDSPKDLVVKEIDSNSALVSWKPLDQVHSNGIITHYEVRYYAPKKEESTERFINVSETSAILSNLKY--------FHYVIYVRAFTKVGGGSWSNPKNYYRQNLEEFPIPTTIK---GERKSETEINISWELPVLSEKNLAHAAIEGFI---ILYAPVESSPKWIKYTVQSKNLSAVIKGLEPDLRYQFQIAATNYAGFNGNFSEIVQEMPKNFPNLNLKTVPDLRCSVQSSNRLKVEWSSPS-------ISTDLLKFEIRYSGNLSYITEIGLKKSEFIDMESKS 2991
+ V ++ +T E D+ P +I Q P + + ++++ C + G+P P+I W N++ ++ + NP +S+K+ L I E D C AEN+ G + S+ L V +P F ++ SN+ L C A G+P P ++W K +E T + G +L + ++ Y C A +T G ++ S + + S P +P + I + +V + W G D+ + +++ Y+ P+N + + IS ++Y Y ++ L P+T Y ++ + N +G PP+ T T T + +PR++ ++S++ +++ W PPE G+ Y++ YT N W V + + ++ L +Y +RV+ +G GP+S + +K G SQ +F+ T+I ++ + LQW P ++ Y L W+ T +H N Y L L + L+A + G+G P ++ G +N+ I ST I+ W PP + + Y++F E + + +N++ E W Y +S + R ILR T + VP D P+D+ ++S S VSWKP + NGII Y + +A + + + F+N ++ L++ Y I V A T+ G G S + P+ T+ ER+ I + WE P + L + + L + S P+ K K + +G+E Y+F++A +N+ G +I Q P+ P ++ Q+ + L V W P+ I+ ++F + L + L+K+ F ++E +
Sbjct: 117 VGDAVSADATLTIYEGDKTPAGFPVITQGPGTRVIEVGHTVLMTCKAIGNPTPNIYWIKNQTKVD--------MSNP--RYSLKD---GFLQIENSREEDQGKYE-CVAENSMGTEHSKATNLYVKVRR--VPPTFSRPPETISEVM--LGSNLNLSCIAVGSPMPHVKWMKG----SEDLTPENEMPIGRNVLQLINIQESANYTCIAASTLG-QIDSVSVVKVQSLPTAPTDVQISEVTATSVRLEWSYKGPEDL---QYYVIQYK--PKNANQ-------AFSEISGIITMY-YVVRALSPYTEYEFYVIAVNNIGRGPPSAPATCTTGETKMESAPRNVQVRTLSSSTMVITWEPPETPNGQVTGYKVYYTTNSNQPEASWNSQMVDNSELTTVSELTPHAIYTVRVQAYTSMGAGPMSTPVQVKAQQGVPSQPSNFRATDIGETAVTLQWTKPTHSSE-NIVHYELY-WN------------DTYANQAHHKRISNSEAYTLDGLYPDTLYYIWLAARSQRGEGATTPPIPVRTKQYVPGAPPRNITAI-ATSSTTISLSWLPPPVERSNGRIIYYKVFFVEVGREDDEATTMTLNMTSIVLDELKRWTEYKIWVLAGTS-----VGDGPRSHPIILR----------TQEDVPGD-PQDVKATPLNSTSIHVSWKPPLEKDRNGIIRGYHI--HAQELRDEGKGFLNEPFKFDVVDTLEFNVTGLQPDTKYSIQVAALTRKGDGDRS--AAIVVKTPGGVPVRPTVSLKIMEREPIVSIELEWERPAQTYGELRGYRLRWGVKDQALKEEMLSGPQMTK-----KRFDNLERGVE----YEFRVAGSNHIGIGQETVKIFQ-TPEGTPG---GPPSNITIRFQTPDVLCVTWDPPTREHRNGIITRYDVQFHKKIDHGLGSERNMTLRKAVFTNLEENT 977 HSP 3 Score: 138.658 bits (348), Expect = 3.781e-32 Identity = 217/921 (23.56%), Postives = 355/921 (38.55%), Query Frame = 1
Query: 289 TFTENDEAPKISLIIQSPNVLLFKSMILACSSTGHPVPSISWKINESPIEELKSPLKKLQNPPRIFSIKNYQNSVLVITQLIESDSNSVLICEAENNAGFDSRQQQLKVISTETDIPSGFPVFQNNFFPIIKPYNSNVTLVCQAYGNPPPLIQWFKNYELINESFTKIKILNDGNLLLVQVTREDKGIYHCQAQNTNGLRLSDPSTLDITSYPISPN-----SLIIERFASDNVEIS------------WRSGLNDVTEQENFILHYREVPENITEKQIMSKFVYLTISEKKSIYKYNLKDLFPFTTYCIWMESENPLGVSPPTIALTVKTLPTSPQLSPRSITATSISNTAILVAW--RPPERKFGKFKYYQIIYTNNDGFLPQHWRQFAVKDDNVMLTHLIASEL-----YHIRVKIVNEIGHGPLSKTISIKTIAGTLSQCP-DFKITEIFQSHIKLQWGTPDPVKLFKLIQYNLLCWDVRLKIVNATAKSSTLFPILNHNLSMN-EMEYVLYLKNEKEIKCRLSAINSDGKG-MPTEIQASTVNKGVNYQ--NLIHIDKIGSTYITFQWRPPSKFS---FDYFLWIYQIFDSEKLDRAVKLPKIKINISDSASAENGWFVYNYTNAFSSSRYILGLRYLCRDSTDILREYVHRSDLVSTMKSVPSDSPKDLVVKEIDSNSALVSWKPLDQVHSNGIITHYEVRYYAPKKEESTERFINVSETSAILSNLK-YFHYVIYVRAFTKVGGGSWSNPKNYYRQNLEEFPI-PTTIKGERKSETEINISWELPVLSEKNLAHAAIEGFIILYAPVESSPKW-----IKYTVQSKNLSAVIKGLEPDLRYQFQIAATNYAGFNGNFSEIVQEMPKNF---PNLNLKTVPDLRCSVQSSNRLKVEWSSPSIS-TDLLKFEIRYS 2922
T + P+I Q+ V + C++ G P PSI W+ N + +S L+ P I S+L I + ++ C AEN G I P+GFPV + V + C+A GNP P I W KN ++ S + L DG L + ED+G Y C A+N+ G S + L + + P I E N+ +S W G D+T PEN E I + L N+++ +T CI + + LG + V++LPT+P + + ++ T++ + W + PE +YY I Y P++ Q + ++ + + L Y V VN IG GP S + T + P + ++ + S + + W P+ ++ Y V T S+ N + N E+ V L R+ A S G G M T +Q +GV Q N D IG T +T QW P+ S Y L+ + ++ + IS+S + Y + + Y + L + + V T + VP P+++ S + +SW P SNG I +Y+V + +E+ + ++ TS +L LK + Y I+V A T VG G S+P Q E+ P P +K + T I++SW+ P+ ++N I G+ I + K K+ V L + GL+PD +Y Q+AA G + IV + P P ++LK + R + S +++EW P+ + +L + +R+
Sbjct: 28 TIVDAAHPPEIIRKPQNQGVRVGGVASFYCAARGDPPPSIVWRKNGKKVSGTQSRYTVLEQPGGI--------SILRIEPVRAGRDDAPYECVAENGVGDAVSADATLTIYEGDKTPAGFPVITQGPGTRVIEVGHTVLMTCKAIGNPTPNIYWIKNQTKVDMSNPRYS-LKDGFLQIENSREEDQGKYECVAENSMGTEHSKATNLYVKVRRVPPTFSRPPETISEVMLGSNLNLSCIAVGSPMPHVKWMKGSEDLT------------PEN--EMPIGRNVLQLI----------NIQESANYT--CI---AASTLGQIDSVSVVKVQSLPTAPT----DVQISEVTATSVRLEWSYKGPE----DLQYYVIQYK------PKNANQAFSEISGIITMYYVVRALSPYTEYEFYVIAVNNIGRGPPSAPATCTTGETKMESAPRNVQVRTLSSSTMVITWEPPE-TPNGQVTGYK----------VYYTTNSNQPEASWNSQMVDNSELTTVSELTPHAIYTVRVQAYTSMGAGPMSTPVQVK-AQQGVPSQPSNFRATD-IGETAVTLQWTKPTHSSENIVHYELYWNDTYANQAHHK---------RISNSEA-------YTLDGLYPDTLYYIWLAARSQRGEGATTPPIP----VRTKQYVPGAPPRNITAIATSSTTISLSWLPPPVERSNGRIIYYKVFFVEVGREDDEATTMTLNMTSIVLDELKRWTEYKIWVLAGTSVGDGPRSHPIILRTQ--EDVPGDPQDVKATPLNSTSIHVSWKPPLEKDRN---GIIRGYHIHAQELRDEGKGFLNEPFKFDV-VDTLEFNVTGLQPDTKYSIQVAALTRKGDGDRSAAIVVKTPGGVPVRPTVSLKIME--REPIVS---IELEWERPAQTYGELRGYRLRWG 852 HSP 4 Score: 102.064 bits (253), Expect = 4.798e-21 Identity = 121/479 (25.26%), Postives = 201/479 (41.96%), Query Frame = 1
Query: 2170 LVSTMKSVPSDSPKDLVVKEIDSNSALVSWKPLDQVHSNGIITHYEVRYYAPKKEESTERFINVSETSAILSNLKY-FHYVIYVRAFTKVGGGSWSNPKNYYRQNLEEFPIPTTIKGERKSETEINISWELPVLSEKNLAHAAIEGFIILY--APVESSPKWIKYTVQSKNLSAVIKGLEPDLRYQFQIAATNYAGFNGNFSE--IVQEMPKNFPNLNLKTVPDLRCSVQSSNRLKVEWSSPSISTDLLKFEIRYSGNLSYITEIGLKKSEFIDMESKSVNFETLVNRYDVTLENLQSNALYKIAVRAIYQNKELYESHRETTCDTMPAVPNLVKPPIIVGLDEEKSKVIIKLHRCSQRNGKISYYFVIVAAFQGNKNQQISFQEDTESYTFMELSVNTRSNNAKGEYIAI---MKDINDIFKVSGKDHSSVLLGDGTHDENHLSVNKKLEKNFNYRCFARVCLKYSNNSLCKSSPWSE 3582
+ T + P P ++ ++ + V+W P + H NGIIT Y+V+++ K + N++ A+ +NL+ Y+ VRA+TK G G +S+ K + P +++ E SE I WE PV S L G+ I Y VE W TV SA + LE +Y IAA G G SE V+ P++ P LN LR S++ + + W SP I + ++I + ++ G +++ + + + + V + T+ L Y + V AI + + T M A +VKP ++ E ++++ L + S+ G IS+Y+++V + +I Q T+ L + YIA + I F + G+ D+ H N+KLE+ YR F R + L SSP+SE
Sbjct: 901 IFQTPEGTPGGPPSNITIRFQTPDVLCVTWDPPTREHRNGIITRYDVQFHK-KIDHGLGSERNMTLRKAVFTNLEENTEYIFRVRAYTKQGAGPFSD-KLIVETERDMGRAPMSLQAEATSEQTAEIWWE-PVTSRGKLL-----GYKIFYTMTAVEDLDDWQTKTV-GLTESADLVNLEKFAQYAVAIAARFKNGL-GRLSEKVTVRIKPEDVP-LN------LRAHDVSTHSMTLSW-SPPIRLTPVNYKISFDAMKVFVDSQGFSQTQIV--PKREIILKHYVKTH--TINELSPFTTYNVNVSAIPSDYSYRPPTKITVTTQMAAPQPMVKPDFYGVVNGE--EILVILPQASEEYGPISHYYLVVVPEDKSNLHKIPDQFLTDDL----LPGRNKPERPNAPYIAAKFPQRSIPFTFHL------------GSGDDYHNFTNRKLEREKRYRIFVRAVVDTPQKHLYTSSPFSE 1339 HSP 5 Score: 53.5286 bits (127), Expect = 2.452e-6 Identity = 63/300 (21.00%), Postives = 119/300 (39.67%), Query Frame = 1
Query: 2203 SPKDLVVKEIDSNSALVSWKPLDQVHSNGIITHYEVRYYAPKKEESTE---RFINVSETSAILSNLKYFHYVIYVRAFTKVGGGSWSNPKNYYRQNLEEFPI-PTTIKGERKSETEINISWELPVLSEKNLAHAAIEGFIILYAPVESSPKWIKYTVQSKNLSAVIKGLEPDLRYQFQIAATNYAGFNGNFSEIVQEMPKNFPNLNLKTVPDLRCSVQSSNRLKVEWSSPSISTDLLKFEIRYSGNLSY----ITEIGLKKSEFIDMESKSVNFETLVNRYDVTLENLQSNALYKIAVRA 3078
+P+++ V+ + S++ +++W+P + NG +T Y+V Y + + ++ SE + + + Y + V+A+T +G G S P Q + P P+ + ET + + W P S +N+ H + + YA + S + + + GL PD Y +AA + G I + P + + + SS + + W P + R +G + Y E+G + E M +N + L+ L+ YKI V A
Sbjct: 419 APRNVQVRTLSSSTMVITWEPPET--PNGQVTGYKVYYTTNSNQPEASWNSQMVDNSELTTVSELTPHAIYTVRVQAYTSMGAGPMSTPVQVKAQ--QGVPSQPSNFRATDIGETAVTLQWTKPTHSSENIVHYELY-WNDTYA------NQAHHKRISNSEAYTLDGLYPDTLYYIWLAARSQRGEGATTPPIPVRTKQYVPGAPPRNITAI---ATSSTTISLSWLPPPVE--------RSNGRIIYYKVFFVEVGREDDEATTM---------TLNMTSIVLDELKRWTEYKIWVLA 687
BLAST of Protein tyrosine phosphatase receptor type D vs. Ensembl Fly
Match: Lar (gene:FBgn0000464 transcript:FBtr0331239) HSP 1 Score: 665.611 bits (1716), Expect = 0.000e+0 Identity = 324/630 (51.43%), Postives = 424/630 (67.30%), Query Frame = 1
Query: 3937 PDLVNADSVQMCQD-GTKLSPVLVSDSIKLRIGSQKSENISDRPSISICNLYQYVTDLKANDCTLLQAEFETLNTNLDDRFTWQRSNIDSNKSKNRYANVVAYDHTSVLLTPVDDVIGSDYINANYIDGYQRQNAYIATQGPLPDTTDDFWRMVWEQRSNCIVMMTRLEERSGIKCHQYWPNRGFICYGQMIVSHIDTFVLAYYTIRLFEIRHSKYSEKREIQHFQFTAWPDHGVPKLSTPLLMFIRRVRSIGKIESCPKIVHCSAGVGRTGAFIVVDAQLERIKQEKNIDVFNYVSKIRCQRNYMVQTQAQYQFILETLLEAVEDGNTEVMACNFHAHVTKLSQIGISGSNQLSGFEMEFSKLNSLASNRGRHGVMLADFVKAAGNQAVNMTKNRVRNIIPYEWNRVVLNAIRGIEGSDYINASYIDGYRDRRAYIAAQSPIPSTVEDFWRMLWDQHCGVVIVLNQPHE---DKSHIYWPINKSIRYQFFVVDPVVEYNMPNYILREFKVTDARDGEFRALRQFQFTQWPNHGCPKESESILDFIRQVHKTKEQFGHMEPMVIHCNTGSGRTGVFIALSIVLDRLQQESVVDMYQTVKLLHKQRIGLVQTEEQYEFCYMAVLDYLSNYE 5814
PD M D G +P SD + +R + ++ + P I I ++ LK+ND E+E++ +FTW SN++ NKSKNRYANV AYDH+ V L V+ V+GSDYINANY DGY++ NAY+ATQGPL +T DFWRM WE ++ IVMMTRLEER+ IKC QYWP RG YGQ+ V+ +T LA Y+IR F++ ++++REI+ QFTAWPDHGVP P L F+RR R++ ES P IVHCSAGVGRTG +IV+D+ LER+K EK ID++ +V+ +R QRNYMVQT+ QY FI + +LEA+ G TEV A N H H+ KL + +SG E+EF KL+++ + + FV A N N KNR+ +I+PYE +RV L I GIEGSDY+NAS+IDGYR R AYIAAQ P+ EDFWRMLW+ + +V++L + E +K YWP +S+RYQ++VVDP+ EYNMP Y LREFKVTDARDG R +RQFQF WP G PK E +DFI QVHKTKEQFG P+ +HC+ G GR+GVFI LSIVL+R+Q E V+D++QTV++L QR +VQTE+QY FCY A L+YL +++
Sbjct: 1415 PDQAAVTRPLMAADLGAGPTP---SDPVDMRRLNFQTPGMISHPPIPISEFANHIERLKSNDNQKFSQEYESIEPG--QQFTWDNSNLEHNKSKNRYANVTAYDHSRVQLPAVEGVVGSDYINANYCDGYRKHNAYVATQGPLQETFVDFWRMCWELKTATIVMMTRLEERTRIKCDQYWPTRGTETYGQIFVTITETQELATYSIRTFQLCRQGFNDRREIKQLQFTAWPDHGVPDHPAPFLQFLRRCRALTPPESGPVIVHCSAGVGRTGCYIVIDSMLERMKHEKIIDIYGHVTCLRAQRNYMVQTEDQYIFIHDAILEAIICGVTEVPARNLHTHLQKL--LITEPGETISGMEVEFKKLSNVKMDSSK-------FVTA--NLPCNKHKNRLVHILPYESSRVYLTPIHGIEGSDYVNASFIDGYRYRSAYIAAQGPVQDAAEDFWRMLWEHNSTIVVMLTKLKEMGREKCFQYWPHERSVRYQYYVVDPIAEYNMPQYKLREFKVTDARDGSSRTVRQFQFIDWPEQGVPKSGEGFIDFIGQVHKTKEQFGQDGPITVHCSAGVGRSGVFITLSIVLERMQYEGVLDVFQTVRILRSQRPAMVQTEDQYHFCYRAALEYLGSFD 2028 HSP 2 Score: 160.999 bits (406), Expect = 6.194e-39 Identity = 216/948 (22.78%), Postives = 389/948 (41.03%), Query Frame = 1
Query: 256 ITQLVLINSQITFTENDEAPK-ISLIIQSPNVLLFK---SMILACSSTGHPVPSISWKINESPIEELKSPLKKLQNPPRIFSIKNYQNSVLVITQLIESDSNSVLICEAENNAGFD-SRQQQLKVISTETDIPSGFPVFQNNFFPIIKPYNSNVTLVCQAYGNPPPLIQWFKNYELINESFTKIKILNDGNLLLVQVTREDKGIYHCQAQNTNGLRLSDPSTLDITSYPISPNSLIIERFASDNVEISWR-SGLNDVTEQENFILHYREVPENITEKQIMSKFVYLTISEKKSIYKYNLKDLFPFTTYCIWMESENPLGVSPPTIALTVKTL-----PTSPQLSPRSITATSISNTAILVAWRPPERKFGKFKYYQIIYTNNDGFLPQHWRQFAVKDDNVM-LTHLIASELYHIRVKIVNEIGHGPLSKTISIKTIAGTLSQCPDFKITEIFQSHIKLQWGTPDPVKLFKLIQYNLLCWDVRLKIVNATAKSSTLFPILNHNLSMNEMEYVL-YLKNEKEIKCRLSAINSDGKGMPT-EIQASTVNKGVNYQNLIHIDKIGSTYITFQWRPPSKFSFDYFLWIYQIFDSEKLDRAVKLPKIKINISDSASAE-NGWFVYNYTNAFSSSRYILGLRYLCRDSTDILREYVHRSDLVSTMKSVPSDSPKDLVVKEIDSNSALVSWKPLDQVHSNGIITHYEVRYYAPKKEESTERFINVSETSAILSNLKY--------FHYVIYVRAFTKVGGGSWSNPKNYYRQNLEEFPIPTTIK---GERKSETEINISWELPVLSEKNLAHAAIEGFI---ILYAPVESSPKWIKYTVQSKNLSAVIKGLEPDLRYQFQIAATNYAGFNGNFSEIVQEMPKNFPNLNLKTVPDLRCSVQSSNRLKVEWSSPS-------ISTDLLKFEIRYSGNLSYITEIGLKKSEFIDMESKS 2991
+ V ++ +T E D+ P +I Q P + + ++++ C + G+P P+I W N++ ++ + NP +S+K+ L I E D C AEN+ G + S+ L V +P F ++ SN+ L C A G+P P ++W K +E T + G +L + ++ Y C A +T G ++ S + + S P +P + I + +V + W G D+ + +++ Y+ P+N + + IS ++Y Y ++ L P+T Y ++ + N +G PP+ T T T + +PR++ ++S++ +++ W PPE G+ Y++ YT N W V + + ++ L +Y +RV+ +G GP+S + +K G SQ +F+ T+I ++ + LQW P ++ Y L W+ T +H N Y L L + L+A + G+G T I T G +N+ I ST I+ W PP + + Y++F E + + +N++ E W Y +S + R ILR T + VP D P+D+ ++S S VSWKP + NGII Y + +A + + + F+N ++ L++ Y I V A T+ G G S + P+ T+ ER+ I + WE P + L + + L + S P+ K K + +G+E Y+F++A +N+ G +I Q P+ P ++ Q+ + L V W P+ I+ ++F + L + L+K+ F ++E +
Sbjct: 117 VGDAVSADATLTIYEGDKTPAGFPVITQGPGTRVIEVGHTVLMTCKAIGNPTPNIYWIKNQTKVD--------MSNP--RYSLKD---GFLQIENSREEDQGKYE-CVAENSMGTEHSKATNLYVKVRR--VPPTFSRPPETISEVM--LGSNLNLSCIAVGSPMPHVKWMKG----SEDLTPENEMPIGRNVLQLINIQESANYTCIAASTLG-QIDSVSVVKVQSLPTAPTDVQISEVTATSVRLEWSYKGPEDL---QYYVIQYK--PKNANQ-------AFSEISGIITMY-YVVRALSPYTEYEFYVIAVNNIGRGPPSAPATCTTGDFSFGGTKMESAPRNVQVRTLSSSTMVITWEPPETPNGQVTGYKVYYTTNSNQPEASWNSQMVDNSELTTVSELTPHAIYTVRVQAYTSMGAGPMSTPVQVKAQQGVPSQPSNFRATDIGETAVTLQWTKPTHSSE-NIVHYELY-WN------------DTYANQAHHKRISNSEAYTLDGLYPDTLYYIWLAARSQRGEGATTPPIPVRTKQYGAPPRNITAI-ATSSTTISLSWLPPPVERSNGRIIYYKVFFVEVGREDDEATTMTLNMTSIVLDELKRWTEYKIWVLAGTS-----VGDGPRSHPIILR----------TQEDVPGD-PQDVKATPLNSTSIHVSWKPPLEKDRNGIIRGYHI--HAQELRDEGKGFLNEPFKFDVVDTLEFNVTGLQPDTKYSIQVAALTRKGDGDRS--AAIVVKTPGGVPVRPTVSLKIMEREPIVSIELEWERPAQTYGELRGYRLRWGVKDQALKEEMLSGPQMTK-----KRFDNLERGVE----YEFRVAGSNHIGIGQETVKIFQ-TPEGTPG---GPPSNITIRFQTPDVLCVTWDPPTREHRNGIITRYDVQFHKKIDHGLGSERNMTLRKAVFTNLEENT 980 HSP 3 Score: 135.191 bits (339), Expect = 3.939e-31 Identity = 205/874 (23.46%), Postives = 346/874 (39.59%), Query Frame = 1
Query: 1051 ENITEKQIMSKFVYLTISEKKSIY---KYNLKDLFPFTTYCIWMESENPLGVSPPTIALTVKTLPTSPQLSPRSITATSISNTAILVAWRPP--ERKFGKFKYYQIIYTNNDGFLPQHWRQFAVKDDNVM-----LTHLIASEL-----YHIRVKIVNEIGHGPLSKTISIKTIAGTLSQCPDFKITEIFQSHIKLQWGTPDPVKLFKLIQ-YNLLCWDVRLK---IVNATAKSSTLFPILNHNLSMNEMEYVLYLKNEKEIKCRLSAINSDGKGMPTEIQASTVNKGVNYQNLIHI---DKIGSTYITFQWRPPSKFSFDYFLWIYQIFDSEKLDRAVKLPKIKINISDSASAENGWFVYNYTNAFSSSRYILGLRYLCRDSTDILREYVHRSDLVSTMKSVPSDSPKDLVVKEIDSNSALVSWKPLDQVHSNGIITHYEVRYYAPKKEESTERFINVSETSAILSNLKY-FHYVIYVRAFTKVGGGSWSNPKNYYRQNLEEFPIPTTIKGERKSETEINISWELPVLSEKNLAHAAIEGFIILY--APVESSPKWIKYTVQSKNLSAVIKGLEPDLRYQFQIAATNYAGFNGNFSE--IVQEMPKNFPNLNLKTVPDLRCSVQSSNRLKVEWSSPSISTDLLKFEIRYSGNLSYITEIGLKKSEFIDMESKSVNFETLVNRYDVTLENLQSNALYKIAVRAIYQNKELYESHRETTCDTMPAVPNLVKPPIIVGLDEEKSKVIIKLHRCSQRNGKISYYFVIVAAFQGNKNQQISFQEDTESYTFMELSVNTRSNNAKGEYIAI---MKDINDIFKVSGKDHSSVLLGDGTHDENHLSVNKKLEKNFNYRCFARVCLKYSNNSLCKSSPWSE 3582
ENI ++ Y + K I Y L L+P T Y IW+ + + G T + V+T PR+ITA + S+T I ++W PP ER G+ YY++ + + +DD +T ++ EL Y I V +G GP S I ++T D K T + + I + W P +I+ Y++ ++R + +N K F +++ L N V L+ + + +++A+ G G + GV + + + ++ I +W P++ Y +L VK +K + F N Y R + I +E V + T + P P ++ ++ + V+W P + H NGIIT Y+V+++ K + N++ A+ +NL+ Y+ VRA+TK G G +S+ K + P +++ E SE I WE PV S L G+ I Y VE W TV SA + LE +Y IAA G G SE V+ P++ P LN LR S++ + + W SP I + ++I + ++ G +++ + + + + V + T+ L Y + V AI + + T M A +VKP ++ E ++++ L + S+ G IS+Y+++V + +I Q T+ L + YIA + I F + G+ D+ H N+KLE+ YR F R + L SSP+SE
Sbjct: 548 ENIVHYELYWNDTYANQAHHKRISNSEAYTLDGLYPDTLYYIWLAARSQRGEGATTPPIPVRTKQYG--APPRNITAIATSSTTISLSWLPPPVERSNGRIIYYKVFFV-----------EVGREDDEATTMTLNMTSIVLDELKRWTEYKIWVLAGTSVGDGPRSHPIILRTQEDVPGDPQDVKATPLNSTSIHVSWKPPLEKDRNGIIRGYHIHAQELRDEGKGFLNEPFK----FDVVD-TLEFN----VTGLQPDTKYSIQVAALTRKGDGDRSAAIVVKTPGGVPVRPTVSLKIMEREPIVSIELEWERPAQ--------TYGELRGYRLRWGVKDQALKEEMLSGPQMTKKRF----DNLERGVEY--EFRVAGSNHIGIGQETV---KIFQTPEGTPGGPPSNITIRFQTPDVLCVTWDPPTREHRNGIITRYDVQFHK-KIDHGLGSERNMTLRKAVFTNLEENTEYIFRVRAYTKQGAGPFSD-KLIVETERDMGRAPMSLQAEATSEQTAEIWWE-PVTSRGKLL-----GYKIFYTMTAVEDLDDWQTKTV-GLTESADLVNLEKFAQYAVAIAARFKNGL-GRLSEKVTVRIKPEDVP-LN------LRAHDVSTHSMTLSW-SPPIRLTPVNYKISFDAMKVFVDSQGFSQTQIV--PKREIILKHYVKTH--TINELSPFTTYNVNVSAIPSDYSYRPPTKITVTTQMAAPQPMVKPDFYGVVNGE--EILVILPQASEEYGPISHYYLVVVPEDKSNLHKIPDQFLTDDL----LPGRNKPERPNAPYIAAKFPQRSIPFTFHL------------GSGDDYHNFTNRKLEREKRYRIFVRAVVDTPQKHLYTSSPFSE 1342 HSP 4 Score: 127.487 bits (319), Expect = 9.666e-29 Identity = 217/932 (23.28%), Postives = 355/932 (38.09%), Query Frame = 1
Query: 289 TFTENDEAPKISLIIQSPNVLLFKSMILACSSTGHPVPSISWKINESPIEELKSPLKKLQNPPRIFSIKNYQNSVLVITQLIESDSNSVLICEAENNAGFDSRQQQLKVISTETDIPSGFPVFQNNFFPIIKPYNSNVTLVCQAYGNPPPLIQWFKNYELINESFTKIKILNDGNLLLVQVTREDKGIYHCQAQNTNGLRLSDPSTLDITSYPISPN-----SLIIERFASDNVEIS------------WRSGLNDVTEQENFILHYREVPENITEKQIMSKFVYLTISEKKSIYKYNLKDLFPFTTYCIWMESENPLGVSPPTIALTVKTLPTSPQLSPRSITATSISNTAILVAW--RPPERKFGKFKYYQIIYTNNDGFLPQHWRQFAVKDDNVMLTHLIASEL-----YHIRVKIVNEIGHGPLSKTISIKT----IAGT-LSQCP-DFKITEIFQSHIKLQWGTPDPVKLFKLIQYNLLCWDVRLKIVNATAKSSTLFPILNHNLSMN-EMEYVLYLKNEKEIKCRLSAINSDGKG-MPTEIQASTVNKGVNYQ--NLIHIDKIGSTYITFQWRPPSKFS---FDYFLWIYQIFDSEKLDRAVKLPKIKINISDSASAENGWFVYNYTNAFSSSRYILGLRYLCRDSTDILREYVHRSDLVSTMKSVP------SDSPKDLVVKEIDSNSALVSWKPLDQVHSNGIITHYEVRYYAPKKEESTERFINVSETSAILSNLK-YFHYVIYVRAFTKVGGGSWSNPKNYYRQNLEEFPI-PTTIKGERKSETEINISWELPVLSEKNLAHAAIEGFIILYAPVESSPKW-----IKYTVQSKNLSAVIKGLEPDLRYQFQIAATNYAGFNGNFSEIVQEMPKNF---PNLNLKTVPDLRCSVQSSNRLKVEWSSPSIS-TDLLKFEIRYS 2922
T + P+I Q+ V + C++ G P PSI W+ N + +S L+ P I S+L I + ++ C AEN G I P+GFPV + V + C+A GNP P I W KN ++ S + L DG L + ED+G Y C A+N+ G S + L + + P I E N+ +S W G D+T PEN E I + L N+++ +T CI + + LG + V++LPT+P + + ++ T++ + W + PE +YY I Y P++ Q + ++ + + L Y V VN IG GP S + T GT + P + ++ + S + + W P+ ++ Y V T S+ N + N E+ V L R+ A S G G M T +Q +GV Q N D IG T +T QW P+ S Y L+ + ++ + IS+S + Y + + Y + L + +T +P P+++ S + +SW P SNG I +Y+V + +E+ + ++ TS +L LK + Y I+V A T VG G S+P Q E+ P P +K + T I++SW+ P+ ++N I G+ I + K K+ V L + GL+PD +Y Q+AA G + IV + P P ++LK + R + S +++EW P+ + +L + +R+
Sbjct: 28 TIVDAAHPPEIIRKPQNQGVRVGGVASFYCAARGDPPPSIVWRKNGKKVSGTQSRYTVLEQPGGI--------SILRIEPVRAGRDDAPYECVAENGVGDAVSADATLTIYEGDKTPAGFPVITQGPGTRVIEVGHTVLMTCKAIGNPTPNIYWIKNQTKVDMSNPRYS-LKDGFLQIENSREEDQGKYECVAENSMGTEHSKATNLYVKVRRVPPTFSRPPETISEVMLGSNLNLSCIAVGSPMPHVKWMKGSEDLT------------PEN--EMPIGRNVLQLI----------NIQESANYT--CI---AASTLGQIDSVSVVKVQSLPTAPT----DVQISEVTATSVRLEWSYKGPE----DLQYYVIQYK------PKNANQAFSEISGIITMYYVVRALSPYTEYEFYVIAVNNIGRGPPSAPATCTTGDFSFGGTKMESAPRNVQVRTLSSSTMVITWEPPE-TPNGQVTGYK----------VYYTTNSNQPEASWNSQMVDNSELTTVSELTPHAIYTVRVQAYTSMGAGPMSTPVQVK-AQQGVPSQPSNFRATD-IGETAVTLQWTKPTHSSENIVHYELYWNDTYANQAHHK---------RISNSEA-------YTLDGLYPDTLYYIWLAARSQRGEG------------ATTPPIPVRTKQYGAPPRNITAIATSSTTISLSWLPPPVERSNGRIIYYKVFFVEVGREDDEATTMTLNMTSIVLDELKRWTEYKIWVLAGTSVGDGPRSHPIILRTQ--EDVPGDPQDVKATPLNSTSIHVSWKPPLEKDRN---GIIRGYHIHAQELRDEGKGFLNEPFKFDV-VDTLEFNVTGLQPDTKYSIQVAALTRKGDGDRSAAIVVKTPGGVPVRPTVSLKIME--REPIVS---IELEWERPAQTYGELRGYRLRWG 855 HSP 5 Score: 53.1434 bits (126), Expect = 3.183e-6 Identity = 65/301 (21.59%), Postives = 120/301 (39.87%), Query Frame = 1
Query: 2203 SPKDLVVKEIDSNSALVSWKPLDQVHSNGIITHYEVRYYAPKKEESTE---RFINVSETSAILSNLKYFHYVIYVRAFTKVGGGSWSNPKNYYRQNLEEFPI-PTTIKGERKSETEINISWELPVLSEKNLAHAAIEGFIILYAPVESSPKWIKYTVQSKNLSAVIKGLEPDLRYQFQIAATNYAGFNGNFSEI-VQEMPKNFPNLNLKTVPDLRCSVQSSNRLKVEWSSPSISTDLLKFEIRYSGNLSY----ITEIGLKKSEFIDMESKSVNFETLVNRYDVTLENLQSNALYKIAVRA 3078
+P+++ V+ + S++ +++W+P + NG +T Y+V Y + + ++ SE + + + Y + V+A+T +G G S P Q + P P+ + ET + + W P S +N+ H + + YA + S + + + GL PD Y +AA + G I V+ P N+ + SS + + W P + R +G + Y E+G + E M +N + L+ L+ YKI V A
Sbjct: 424 APRNVQVRTLSSSTMVITWEPPET--PNGQVTGYKVYYTTNSNQPEASWNSQMVDNSELTTVSELTPHAIYTVRVQAYTSMGAGPMSTPVQVKAQ--QGVPSQPSNFRATDIGETAVTLQWTKPTHSSENIVHYELY-WNDTYA------NQAHHKRISNSEAYTLDGLYPDTLYYIWLAARSQRGEGATTPPIPVRTKQYGAPPRNITAI------ATSSTTISLSWLPPPVE--------RSNGRIIYYKVFFVEVGREDDEATTM---------TLNMTSIVLDELKRWTEYKIWVLA 690
BLAST of Protein tyrosine phosphatase receptor type D vs. Ensembl Zebrafish
Match: ptprfa (protein tyrosine phosphatase receptor type Fa [Source:ZFIN;Acc:ZDB-GENE-020107-2]) HSP 1 Score: 720.694 bits (1859), Expect = 0.000e+0 Identity = 331/606 (54.62%), Postives = 440/606 (72.61%), Query Frame = 1
Query: 4006 SDSIKLRIGSQKSENISDRPSISICNLYQYVTDLKANDCTLLQAEFETLNTNLDDRFTWQRSNIDSNKSKNRYANVVAYDHTSVLLTPVDDVIGSDYINANYIDGYQRQNAYIATQGPLPDTTDDFWRMVWEQRSNCIVMMTRLEERSGIKCHQYWPNRGFICYGQMIVSHIDTFVLAYYTIRLFEIRHSKYSEKREIQHFQFTAWPDHGVPKLSTPLLMFIRRVRSIGKIESCPKIVHCSAGVGRTGAFIVVDAQLERIKQEKNIDVFNYVSKIRCQRNYMVQTQAQYQFILETLLEAVEDGNTEVMACNFHAHVTKLSQIGISGSNQLSGFEMEFSKLNSLASNRGRHGVMLADFVKAAGNQAVNMTKNRVRNIIPYEWNRVVLNAIRGIEGSDYINASYIDGYRDRRAYIAAQSPIPSTVEDFWRMLWDQHCGVVIVLNQPHE---DKSHIYWPINKSIRYQFFVVDPVVEYNMPNYILREFKVTDARDGEFRALRQFQFTQWPNHGCPKESESILDFIRQVHKTKEQFGHMEPMVIHCNTGSGRTGVFIALSIVLDRLQQESVVDMYQTVKLLHKQRIGLVQTEEQYEFCYMAVLDYLSNYE 5814
SD +++R + +++ + + P +S+C L ++ L+AND E+E+++ +FTW+ SN++ NK KNRYANV+AYDH+ V+LTPVD V GSDYIN NYIDGY++QNAYIATQGPLP+T DFWRMVWEQR++ IVMMTRLEE+S +KC QYWP+RG YG + VS +DT LA Y++R F + + SEKRE++ FQF AWPDHGVP+ TP+L F+RRV++ ++ P +VHCSAGVGRTG FIV+DA LER+K EK++D++ +V+ +R QRNYMVQT+ QY FI E LLEA GNTEV A + + H+ KL+Q + ++ E+EF KL + ++ R F+ A+ N KNR+ NI+P+E +RV L IRG+EGSDYINAS+IDGYR ++AYIA Q P+ T EDFWRMLW+ + +V++L + E +K H YWP +S RYQ+FVVDP+ EYNMP YILREFKVTDARDG+ R +RQFQFT WP G PK E +DFI QVHKTKEQFG P+ +HC+ G GRTGVFI LSIVL+R++ E VVDM+QT+K L QR +VQTE+QY+ CY A L+YL +++
Sbjct: 1301 SDPVEMRRLNYQTQGMREHPPVSVCALADHIERLRANDSLRFSQEYESVDPG--QQFTWENSNLEVNKPKNRYANVIAYDHSRVVLTPVDGVPGSDYINGNYIDGYRKQNAYIATQGPLPETLSDFWRMVWEQRTSTIVMMTRLEEKSRVKCDQYWPSRGTETYGMIQVSMLDTVELATYSVRTFALYKNGSSEKREVRQFQFMAWPDHGVPEYPTPILAFLRRVKACNPPDAGPMVVHCSAGVGRTGCFIVIDAMLERMKHEKSVDIYGHVTCMRSQRNYMVQTEDQYIFIHEALLEAATCGNTEVPARSLYTHIQKLTQ--APPGDTVTAMELEFKKLANSKAHTSR-------FISAS--LPCNKFKNRLVNIMPFESSRVCLQPIRGVEGSDYINASFIDGYRQQKAYIATQGPLSETTEDFWRMLWEHNSTIVVMLTKLREMGREKCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDARDGQSRTIRQFQFTDWPEQGVPKTGEGFIDFIGQVHKTKEQFGQDGPITVHCSAGVGRTGVFITLSIVLERMRYEGVVDMFQTIKTLRTQRPAMVQTEDQYQLCYRAALEYLGSFD 1893 HSP 2 Score: 202.601 bits (514), Expect = 1.585e-51 Identity = 103/263 (39.16%), Postives = 150/263 (57.03%), Query Frame = 1
Query: 5092 NQAVNMTKNRVRNIIPYEWNRVVLNAIRGIEGSDYINASYIDGYRDRRAYIAAQSPIPSTVEDFWRMLWDQHCGVVIVLNQPHEDKSHI----YWPINKSIRYQFFVVDPVVEYNMPNYILREFKVTDARDGEFRALRQFQFTQWPNHGCPKESESILDFIRQVHKTKEQFGHMEPMVIHCNTGSGRTGVFIALSIVLDRLQQESVVDMYQTVKLLHKQRIGLVQTEEQYEFCYMAVLDYLSNYEKILEKSHLY*TYQDLSES 5868
N VN KNR N+I Y+ +RVVL + G+ GSDYIN +YIDGYR + AYIA Q P+P T+ DFWRM+W+Q ++++ + E+KS + YWP + Y V + + Y +R F + E R +RQFQF WP+HG P+ IL F+R+V PMV+HC+ G GRTG FI + +L+R++ E VD+Y V + QR +VQTE+QY F + A+L+ + + LY Q L+++
Sbjct: 1361 NLEVNKPKNRYANVIAYDHSRVVLTPVDGVPGSDYINGNYIDGYRKQNAYIATQGPLPETLSDFWRMVWEQRTSTIVMMTR-LEEKSRVKCDQYWPSRGTETYGMIQVSMLDTVELATYSVRTFALYKNGSSEKREVRQFQFMAWPDHGVPEYPTPILAFLRRVKACNPP--DAGPMVVHCSAGVGRTGCFIVIDAMLERMKHEKSVDIYGHVTCMRSQRNYMVQTEDQYIFIHEALLEAATCGNTEVPARSLYTHIQKLTQA 1620 HSP 3 Score: 151.369 bits (381), Expect = 7.472e-36 Identity = 231/1011 (22.85%), Postives = 377/1011 (37.29%), Query Frame = 1
Query: 370 LACSSTGHPVPSISWKINESPIEELKSPLKKLQNPPRIFSIKNYQNSVLVITQLIESDSNSVLICEAENNAGFDSRQQQLKVISTETDIPSGFPVFQNNFFPIIKPYNSNVTLVCQAYGNPPPLIQWFKNYEL--INESFTKIKILNDGNLLLVQVTREDKGIYHCQAQNTNGLRLSDPSTLDI------TSYPISPNSLIIERFASDNVE----------ISWRSGLNDVTEQENFILHYREVPENITEKQIMSKFVYLTISEKKSIYKYNLKDLFPFTTYCIWMESENPLGVSPPTIALTVKTLPTSPQLSPRSITATSISNTAILVAWRP--PERKFGKFKYYQIIY---TNNDGFLPQHWRQFAVKDDNVMLTHLIASELYHIRVKIVNEIGHGPLSKTISIKTIAGTLSQCP-DFKITEIFQSHIKLQWGTPDPVKLFKLIQYNLLCWDVRLKIVNATAKSSTLFPI---LNHNLSMNEMEYVLYLKNEKEIKCRLSAINSDGKGMPTEIQASTVNKGVNYQNL-IHIDKIGSTYITFQWRPPSKFSFDYFLWIYQIFDSEKLDRAVKLPKIKINISDSASAENGWFVYNYTNAFSSSRYILGLRYLCRDSTDILREYVHRSDLVSTMKSVPSDSPKDLVVKEIDSNSALVSWKPLDQVHSNGIITHYEVRYYAPKKEESTE---RFINVSETSAILSNL-KYFHYVIYVRAFTKVGGGSWSNPKNYYRQNLEEFPIPTTIKGERKSETEINISWELPVLSEKNLAHAAIEGFIILYAPVESS-PKW---IKYTVQSKNLSAVIKGLEPDLRYQFQIAATNYAGFNGNFSEIVQEMPKNFPNLNLKTVPDLRCSVQSSNRLKVEWSSP-SISTDLLKFEIRYSGNLSYITEIGLKKSEFIDMESKSVNFETLVNRYDVTLENLQSNALYKIAVRAIYQNKELYESHRETTCDTMPAVPNLVKPPIIVGLDEEKSKVIIKLHRCSQRNGKISYYFVIVAAFQGNKNQ 3291
C + G P P I+W +K K + + SVL I L ++ C A N+ G + +L V+ E IP GFP + T++C A GNP P I WFK++ IN S +IK L G L + D+G Y C A N+ G R S P+ L + + I P + + S N+ + W G ++T++E E I + LT N++ +T C+ + S LG+ T +TVK LP P S+ T + T++ + W PE YY I Y +++GF V + L Y RV VN IG GP S + +T S P + + + + +QW P+ + +++ S FP+ HN + + + L + R+ A S G G P++I +GV Q + T I W P + + Y DS+ + P I DS + +Y ++ A +R +GL + T +S PS P+++ + + S+S VSW +G I Y + Y A E+ + I +S +L L K+ Y ++V+A T VG G S Q P ++ + + T + +SW+ P+ ++ H I G+ ++Y+ +E+ P+ I + AVI GL P+ Y +AA G V P P + S N ++W P + +L+ + +RY K E D+ + +F + + VT + + ++K+ + N E Y T D + P +K +VGL +K+ +RNGKI Y V+ ++NQ
Sbjct: 52 FVCQAVGEPKPRITW---------MKKGKKVSSQRFEVIEFDDGSGSVLRIQPLRTHRDEAIYECTATNSVGEINTSAKLTVLE-EDQIPHGFPTIDMGPQLKVVERTRTATMLCAASGNPDPEISWFKDFLPVDINSSNGRIKQLRSGALQIENSEESDQGKYECVAVNSAGTRYSAPANLYVRVRRVPPRFSIPPTNHEVMPGGSVNLTCVAVGAPMPYVKWMKGEQELTKEE--------------EMPIGRNVLELT----------NIRQSGNYT--CVAISS---LGMIDTTAQITVKALPRPPA----SLIVTETTATSVTLTWDSGNPE----PVSYYVIQYRSKISDNGFQ----EVDGVASTRYSIGGLSPYSEYEFRVMAVNNIGRGPPSGMVETRTSEQAPSSPPLRVQARMLSATTMLVQWEPPEEP-------------NGQIRGYRVYYTSDLHFPLSTWQKHNTEDSSLTTISGLVPDITYGLRVLAFTSVGDGPPSDILQVKTQQGVPAQPTGFEAEAELDTRIMLSWLWPVQDQITKYELTYWEADSDNKHHVIFDPAGSYAI-DSLKPDT---LYKFSLA---ARSEMGLGVYTQPIE------------ARTAQSAPSAPPQEVHLISLSSSSIKVSWVAPPAASRHGSIVRYSLAYQAVSGEDQERHEVKDIPADVSSYVLEGLEKWTEYTVWVKAHTDVGPGPESGSTRIRTQEDVPGAPPRRVEVDNINSTALRVSWKPPLQQKQ---HGHIRGYQVVYSRLENGEPRGQPIILDVALPEAQEAVISGLLPETTYSVTVAAYTTKGDGARSKAKVVTTTGAVPGK-----PTMIISTTIGNTALIQWQPPKEMVGELMGYRLRY-------------KREEEDIYTVR-DFRRTDDHFTVTGLHKGATYIFKLCAKNRAGNGEEYSKEISTPEDVPSSYPQNLK---VVGLTTTTTKLAWDPPPLPERNGKIVRYVVVYRDINSHQNQ 954 HSP 4 Score: 140.969 bits (354), Expect = 9.882e-33 Identity = 207/898 (23.05%), Postives = 358/898 (39.87%), Query Frame = 1
Query: 277 NSQITFTENDEAP----KISLIIQSPNVLLFKSMILACSSTGHPVPSISWKINESPIEELKSPLKKLQNPPRIFSIKNYQNSVLVITQLIESDSNSVLICEAENNAGFD-SRQQQLKVISTETDIPSGFPVFQNNFFPIIKPYNSNVTLVCQAYGNPPPLIQWFKNYELINESFTKIKILNDGNLLLVQVTREDKGIYHCQAQNTNGLRLSDPSTLDITSYPISPNSLIIERFASDNVEISWRSGLNDVTEQENFILHYREVPENITEKQIMSKFVYLTISEKKSIY--KYNLKDLFPFTTYCIWMESENPLGVSPPTIALTVKTLPTSPQLSPRSITATSISNTAILVAWRPPERKFGKFKYYQIIYTNNDGFLPQHWRQFAVKDDNV-MLTHLIASELYHIRVKIVNEIGHGPLSKTISIKTIAGTLSQCPDFKITEIFQSHIKLQWGTPDPVKLFKLIQYNLLCWDVRLKIVNATAKSSTLF-PILNHNLSMNEMEYVLYLKNEKEIKCRLSAINSDGKGMPTE-IQASTVNKGVNY-QNLIHIDKIGSTYITFQW-RPPSK---FSFDYFLWIYQIFDSEKLDRAVKLPKIKINISDSA-SAENGWFVYNYTNAFSSSRYILGLRYLCRDSTDILREYVHRSDLVSTMKSVPSDSPKDLVVKEIDSNSALVSWKPLDQVHSNGIITHYEVRYYAPKKEESTERFINV------SETSAILSNLKYFHYVIYVRAFTKVGGGSWSNPKNYYRQNLEEFPIPTTIKGERKSETEINISWELPVLSEKNLAHAAIEGFIILYAPVESSPKWIKYTVQSKNLSA---VIKGLEPDLRYQFQIAATNYAGFNGNFSEIV---QEMPKNFPNLNLKTVPDLRCSVQSSNRLKVEWSSPSI 2886
++++T E D+ P I + Q V ++ + C+++G+P P ISW + P++ S + IK ++ L I ESD C A N+AG S L V P + P +V L C A G P P ++W K + TK + + G +L G Y C A ++ G+ + + + + + P P SLI+ + +V ++W SG + +++ YR SK E + +Y++ L P++ Y + + N +G PP+ + +T +P P + A +S T +LV W PPE G+ + Y++ YT++ F W++ +D ++ ++ L+ Y +RV +G GP S + +KT G +Q F+ + I L W P ++ K Y L W+ ++ K +F P ++ + LK + K L+A + G G+ T+ I+A T + +H+ + S+ I W PP+ S + YQ E +R ++ I ++S W Y + TD+ S + T + VP P+ + V I+S + VSWKP Q +G I Y+V Y + E + I + ++ + I L Y + V A+T G G+ S K PT I T + I W+ P K + + G+ + Y E YTV+ + + GL Y F++ A N AG +S+ + +++P ++P NLK V ++ K+ W P +
Sbjct: 119 SAKLTVLEEDQIPHGFPTIDMGPQLKVVERTRTATMLCAASGNPDPEISWFKDFLPVDINSSNGR----------IKQLRSGALQIENSEESDQGK-YECVAVNSAGTRYSAPANLYVRVRRVPPRFSIPPTNHEVMP-----GGSVNLTCVAVGAPMPYVKWMKG----EQELTKEEEMPIGRNVLELTNIRQSGNYTCVAISSLGM-IDTTAQITVKALPRPPASLIVTETTATSVTLTWDSGNPEPVSY--YVIQYR------------SKISDNGFQEVDGVASTRYSIGGLSPYSEYEFRVMAVNNIGRGPPSGMVETRTSEQAPSSPPLRVQARMLSATTMLVQWEPPEEPNGQIRGYRVYYTSDLHFPLSTWQKHNTEDSSLTTISGLVPDITYGLRVLAFTSVGDGPPSDILQVKTQQGVPAQPTGFEAEAELDTRIMLSWLWPVQDQITK---YELTYWE-----ADSDNKHHVIFDPAGSYAIDS--------LKPDTLYKFSLAARSEMGLGVYTQPIEARTAQSAPSAPPQEVHLISLSSSSIKVSWVAPPAASRHGSIVRYSLAYQAVSGEDQERH-EVKDIPADVSSYVLEGLEKWTEYT---------------VWVKAHTDVGPGPESGSTRIRTQEDVPGAPPRRVEVDNINSTALRVSWKPPLQQKQHGHIRGYQVVYSRLENGEPRGQPIILDVALPEAQEAVISGLLPETTYSVTVAAYTTKGDGARSKAKVVTTTGAVPGK-PTMIISTTIGNTAL-IQWQPP----KEMV-GELMGYRLRYKREEED----IYTVRDFRRTDDHFTVTGLHKGATYIFKLCAKNRAGNGEEYSKEISTPEDVPSSYPQ-NLKVV------GLTTTTTKLAWDPPPL 931 HSP 5 Score: 70.8626 bits (172), Expect = 2.039e-11 Identity = 131/594 (22.05%), Postives = 236/594 (39.73%), Query Frame = 1
Query: 1126 YNLKDLFPFTTYCIWMESENPLGVSPPTIALTVKTLPTSPQLSPRSITATSISNTAILVAW--RPPERKFGKFKYYQIIYTNNDGFLPQHWRQFAVKDDNVMLTHLIASEL-----YHIRVKIVNEIGHGPLSKTISIKTIAGTLSQCPD-FKITEIFQSHIKLQWGTPDPVKLFKLIQYNLLCWDVRLKIVNATAKSSTLFPILNHNLSMNEMEYVLYLKNEKEIKCRLSAINSDGKGMPTEIQASTVNKGV-NYQNLIHIDKIGSTYITFQWRPPSKFSFDYFLWIYQI-FDSEKLDRAVKLPKIKINISDSASAENGWFVYNYTNAFSSSRYILGLRYLCRDSTDILREYVHRSDLVSTMKSVPSDSPKDLVVKEIDSNSALVSWKPLDQVHSNGIITHYEVRYYAPKKEESTERFINVSETSAILSNLKY-FHYVIYVRAFTKVGGG--SWSNPKNYYRQNLEEFPIPTTIKGERKSETEINISWELPVLSEKNLAHAAIEGFIILYAPVESSPKWIKYTVQSKNLSAVIKGLEPDLRYQFQIAATNYAGFNGNFSEIVQEMPKNFPNLNLKTVPDLRCSVQSSNRLKVE 2868
Y + L P T Y + + + +G+ T + +T ++P P+ + S+S+++I V+W P + G Y + Y G + + VKD ++ + L Y + VK ++G GP S + I+T P ++ I + +++ W P K I+ + + ++ N + + IL+ L + + L E ++A + G G ++ + T V +I IG+T + QW+PP + + L Y++ + E+ D + D ++ + V T + YI L ++ EY S +ST + VPS P++L V + + + ++W P NG I Y V Y ++ ++T + LK Y I VRAFT GGG S S ++ EF +K K T + ++WE+P + + F ILY VQ +I L+PD Y F + + GN + +Q+ ++++T PDL + + +L E
Sbjct: 566 YAIDSLKPDTLYKFSLAARSEMGLGVYTQPIEARTAQSAPSAPPQEVHLISLSSSSIKVSWVAPPAASRHGSIVRYSLAYQAVSG---EDQERHEVKDIPADVSSYVLEGLEKWTEYTVWVKAHTDVGPGPESGSTRIRTQEDVPGAPPRRVEVDNINSTALRVSWKPPLQQKQHGHIRGYQVVYS---RLENGEPRGQPI--ILDVALPEAQEAVISGLLPETTYSVTVAAYTTKGDGARSKAKVVTTTGAVPGKPTMIISTTIGNTAL-IQWQPPKEMVGE--LMGYRLRYKREEED--------IYTVRDFRRTDDHFTV---TGLHKGATYIFKL--CAKNRAGNGEEY---SKEISTPEDVPSSYPQNLKVVGLTTTTTKLAWDPPPLPERNGKIVRYVVVYRDINSHQNQTN--GTADTEMTIQGLKPDTTYDIRVRAFTGKGGGPISPSIQSRTMSTSMPEFTKNFGVKAVMK--TSVLLTWEVPETYKSQVP------FKILY-------NQQSVEVQGDLKRKLITRLQPDTDYSFVLMS------RGNSAGGLQQ------QVSIRTAPDLFTTKPAHQKLDPE 1103
BLAST of Protein tyrosine phosphatase receptor type D vs. Ensembl Zebrafish
Match: ptprfa (protein tyrosine phosphatase receptor type Fa [Source:ZFIN;Acc:ZDB-GENE-020107-2]) HSP 1 Score: 720.309 bits (1858), Expect = 0.000e+0 Identity = 331/606 (54.62%), Postives = 440/606 (72.61%), Query Frame = 1
Query: 4006 SDSIKLRIGSQKSENISDRPSISICNLYQYVTDLKANDCTLLQAEFETLNTNLDDRFTWQRSNIDSNKSKNRYANVVAYDHTSVLLTPVDDVIGSDYINANYIDGYQRQNAYIATQGPLPDTTDDFWRMVWEQRSNCIVMMTRLEERSGIKCHQYWPNRGFICYGQMIVSHIDTFVLAYYTIRLFEIRHSKYSEKREIQHFQFTAWPDHGVPKLSTPLLMFIRRVRSIGKIESCPKIVHCSAGVGRTGAFIVVDAQLERIKQEKNIDVFNYVSKIRCQRNYMVQTQAQYQFILETLLEAVEDGNTEVMACNFHAHVTKLSQIGISGSNQLSGFEMEFSKLNSLASNRGRHGVMLADFVKAAGNQAVNMTKNRVRNIIPYEWNRVVLNAIRGIEGSDYINASYIDGYRDRRAYIAAQSPIPSTVEDFWRMLWDQHCGVVIVLNQPHE---DKSHIYWPINKSIRYQFFVVDPVVEYNMPNYILREFKVTDARDGEFRALRQFQFTQWPNHGCPKESESILDFIRQVHKTKEQFGHMEPMVIHCNTGSGRTGVFIALSIVLDRLQQESVVDMYQTVKLLHKQRIGLVQTEEQYEFCYMAVLDYLSNYE 5814
SD +++R + +++ + + P +S+C L ++ L+AND E+E+++ +FTW+ SN++ NK KNRYANV+AYDH+ V+LTPVD V GSDYIN NYIDGY++QNAYIATQGPLP+T DFWRMVWEQR++ IVMMTRLEE+S +KC QYWP+RG YG + VS +DT LA Y++R F + + SEKRE++ FQF AWPDHGVP+ TP+L F+RRV++ ++ P +VHCSAGVGRTG FIV+DA LER+K EK++D++ +V+ +R QRNYMVQT+ QY FI E LLEA GNTEV A + + H+ KL+Q + ++ E+EF KL + ++ R F+ A+ N KNR+ NI+P+E +RV L IRG+EGSDYINAS+IDGYR ++AYIA Q P+ T EDFWRMLW+ + +V++L + E +K H YWP +S RYQ+FVVDP+ EYNMP YILREFKVTDARDG+ R +RQFQFT WP G PK E +DFI QVHKTKEQFG P+ +HC+ G GRTGVFI LSIVL+R++ E VVDM+QT+K L QR +VQTE+QY+ CY A L+YL +++
Sbjct: 1297 SDPVEMRRLNYQTQGMREHPPVSVCALADHIERLRANDSLRFSQEYESVDPG--QQFTWENSNLEVNKPKNRYANVIAYDHSRVVLTPVDGVPGSDYINGNYIDGYRKQNAYIATQGPLPETLSDFWRMVWEQRTSTIVMMTRLEEKSRVKCDQYWPSRGTETYGMIQVSMLDTVELATYSVRTFALYKNGSSEKREVRQFQFMAWPDHGVPEYPTPILAFLRRVKACNPPDAGPMVVHCSAGVGRTGCFIVIDAMLERMKHEKSVDIYGHVTCMRSQRNYMVQTEDQYIFIHEALLEAATCGNTEVPARSLYTHIQKLTQ--APPGDTVTAMELEFKKLANSKAHTSR-------FISAS--LPCNKFKNRLVNIMPFESSRVCLQPIRGVEGSDYINASFIDGYRQQKAYIATQGPLSETTEDFWRMLWEHNSTIVVMLTKLREMGREKCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDARDGQSRTIRQFQFTDWPEQGVPKTGEGFIDFIGQVHKTKEQFGQDGPITVHCSAGVGRTGVFITLSIVLERMRYEGVVDMFQTIKTLRTQRPAMVQTEDQYQLCYRAALEYLGSFD 1889 HSP 2 Score: 202.601 bits (514), Expect = 1.664e-51 Identity = 103/263 (39.16%), Postives = 150/263 (57.03%), Query Frame = 1
Query: 5092 NQAVNMTKNRVRNIIPYEWNRVVLNAIRGIEGSDYINASYIDGYRDRRAYIAAQSPIPSTVEDFWRMLWDQHCGVVIVLNQPHEDKSHI----YWPINKSIRYQFFVVDPVVEYNMPNYILREFKVTDARDGEFRALRQFQFTQWPNHGCPKESESILDFIRQVHKTKEQFGHMEPMVIHCNTGSGRTGVFIALSIVLDRLQQESVVDMYQTVKLLHKQRIGLVQTEEQYEFCYMAVLDYLSNYEKILEKSHLY*TYQDLSES 5868
N VN KNR N+I Y+ +RVVL + G+ GSDYIN +YIDGYR + AYIA Q P+P T+ DFWRM+W+Q ++++ + E+KS + YWP + Y V + + Y +R F + E R +RQFQF WP+HG P+ IL F+R+V PMV+HC+ G GRTG FI + +L+R++ E VD+Y V + QR +VQTE+QY F + A+L+ + + LY Q L+++
Sbjct: 1357 NLEVNKPKNRYANVIAYDHSRVVLTPVDGVPGSDYINGNYIDGYRKQNAYIATQGPLPETLSDFWRMVWEQRTSTIVMMTR-LEEKSRVKCDQYWPSRGTETYGMIQVSMLDTVELATYSVRTFALYKNGSSEKREVRQFQFMAWPDHGVPEYPTPILAFLRRVKACNPP--DAGPMVVHCSAGVGRTGCFIVIDAMLERMKHEKSVDIYGHVTCMRSQRNYMVQTEDQYIFIHEALLEAATCGNTEVPARSLYTHIQKLTQA 1616 HSP 3 Score: 150.984 bits (380), Expect = 7.655e-36 Identity = 231/1011 (22.85%), Postives = 377/1011 (37.29%), Query Frame = 1
Query: 370 LACSSTGHPVPSISWKINESPIEELKSPLKKLQNPPRIFSIKNYQNSVLVITQLIESDSNSVLICEAENNAGFDSRQQQLKVISTETDIPSGFPVFQNNFFPIIKPYNSNVTLVCQAYGNPPPLIQWFKNYEL--INESFTKIKILNDGNLLLVQVTREDKGIYHCQAQNTNGLRLSDPSTLDI------TSYPISPNSLIIERFASDNVE----------ISWRSGLNDVTEQENFILHYREVPENITEKQIMSKFVYLTISEKKSIYKYNLKDLFPFTTYCIWMESENPLGVSPPTIALTVKTLPTSPQLSPRSITATSISNTAILVAWRP--PERKFGKFKYYQIIY---TNNDGFLPQHWRQFAVKDDNVMLTHLIASELYHIRVKIVNEIGHGPLSKTISIKTIAGTLSQCP-DFKITEIFQSHIKLQWGTPDPVKLFKLIQYNLLCWDVRLKIVNATAKSSTLFPI---LNHNLSMNEMEYVLYLKNEKEIKCRLSAINSDGKGMPTEIQASTVNKGVNYQNL-IHIDKIGSTYITFQWRPPSKFSFDYFLWIYQIFDSEKLDRAVKLPKIKINISDSASAENGWFVYNYTNAFSSSRYILGLRYLCRDSTDILREYVHRSDLVSTMKSVPSDSPKDLVVKEIDSNSALVSWKPLDQVHSNGIITHYEVRYYAPKKEESTE---RFINVSETSAILSNL-KYFHYVIYVRAFTKVGGGSWSNPKNYYRQNLEEFPIPTTIKGERKSETEINISWELPVLSEKNLAHAAIEGFIILYAPVESS-PKW---IKYTVQSKNLSAVIKGLEPDLRYQFQIAATNYAGFNGNFSEIVQEMPKNFPNLNLKTVPDLRCSVQSSNRLKVEWSSP-SISTDLLKFEIRYSGNLSYITEIGLKKSEFIDMESKSVNFETLVNRYDVTLENLQSNALYKIAVRAIYQNKELYESHRETTCDTMPAVPNLVKPPIIVGLDEEKSKVIIKLHRCSQRNGKISYYFVIVAAFQGNKNQ 3291
C + G P P I+W +K K + + SVL I L ++ C A N+ G + +L V+ E IP GFP + T++C A GNP P I WFK++ IN S +IK L G L + D+G Y C A N+ G R S P+ L + + I P + + S N+ + W G ++T++E E I + LT N++ +T C+ + S LG+ T +TVK LP P S+ T + T++ + W PE YY I Y +++GF V + L Y RV VN IG GP S + +T S P + + + + +QW P+ + +++ S FP+ HN + + + L + R+ A S G G P++I +GV Q + T I W P + + Y DS+ + P I DS + +Y ++ A +R +GL + T +S PS P+++ + + S+S VSW +G I Y + Y A E+ + I +S +L L K+ Y ++V+A T VG G S Q P ++ + + T + +SW+ P+ ++ H I G+ ++Y+ +E+ P+ I + AVI GL P+ Y +AA G V P P + S N ++W P + +L+ + +RY K E D+ + +F + + VT + + ++K+ + N E Y T D + P +K +VGL +K+ +RNGKI Y V+ ++NQ
Sbjct: 52 FVCQAVGEPKPRITW---------MKKGKKVSSQRFEVIEFDDGSGSVLRIQPLRTHRDEAIYECTATNSVGEINTSAKLTVLE-EDQIPHGFPTIDMGPQLKVVERTRTATMLCAASGNPDPEISWFKDFLPVDINSSNGRIKQLRSGALQIENSEESDQGKYECVAVNSAGTRYSAPANLYVRVRRVPPRFSIPPTNHEVMPGGSVNLTCVAVGAPMPYVKWMKGEQELTKEE--------------EMPIGRNVLELT----------NIRQSGNYT--CVAISS---LGMIDTTAQITVKALPRPPA----SLIVTETTATSVTLTWDSGNPE----PVSYYVIQYRSKISDNGFQ----EVDGVASTRYSIGGLSPYSEYEFRVMAVNNIGRGPPSGMVETRTSEQAPSSPPLRVQARMLSATTMLVQWEPPEEP-------------NGQIRGYRVYYTSDLHFPLSTWQKHNTEDSSLTTISGLVPDITYGLRVLAFTSVGDGPPSDILQVKTQQGVPAQPTGFEAEAELDTRIMLSWLWPVQDQITKYELTYWEADSDNKHHVIFDPAGSYAI-DSLKPDT---LYKFSLA---ARSEMGLGVYTQPIE------------ARTAQSAPSAPPQEVHLISLSSSSIKVSWVAPPAASRHGSIVRYSLAYQAVSGEDQERHEVKDIPADVSSYVLEGLEKWTEYTVWVKAHTDVGPGPESGSTRIRTQEDVPGAPPRRVEVDNINSTALRVSWKPPLQQKQ---HGHIRGYQVVYSRLENGEPRGQPIILDVALPEAQEAVISGLLPETTYSVTVAAYTTKGDGARSKAKVVTTTGAVPGK-----PTMIISTTIGNTALIQWQPPKEMVGELMGYRLRY-------------KREEEDIYTVR-DFRRTDDHFTVTGLHKGATYIFKLCAKNRAGNGEEYSKEISTPEDVPSSYPQNLK---VVGLTTTTTKLAWDPPPLPERNGKIVRYVVVYRDINSHQNQ 954 HSP 4 Score: 140.969 bits (354), Expect = 1.056e-32 Identity = 207/898 (23.05%), Postives = 358/898 (39.87%), Query Frame = 1
Query: 277 NSQITFTENDEAP----KISLIIQSPNVLLFKSMILACSSTGHPVPSISWKINESPIEELKSPLKKLQNPPRIFSIKNYQNSVLVITQLIESDSNSVLICEAENNAGFD-SRQQQLKVISTETDIPSGFPVFQNNFFPIIKPYNSNVTLVCQAYGNPPPLIQWFKNYELINESFTKIKILNDGNLLLVQVTREDKGIYHCQAQNTNGLRLSDPSTLDITSYPISPNSLIIERFASDNVEISWRSGLNDVTEQENFILHYREVPENITEKQIMSKFVYLTISEKKSIY--KYNLKDLFPFTTYCIWMESENPLGVSPPTIALTVKTLPTSPQLSPRSITATSISNTAILVAWRPPERKFGKFKYYQIIYTNNDGFLPQHWRQFAVKDDNV-MLTHLIASELYHIRVKIVNEIGHGPLSKTISIKTIAGTLSQCPDFKITEIFQSHIKLQWGTPDPVKLFKLIQYNLLCWDVRLKIVNATAKSSTLF-PILNHNLSMNEMEYVLYLKNEKEIKCRLSAINSDGKGMPTE-IQASTVNKGVNY-QNLIHIDKIGSTYITFQW-RPPSK---FSFDYFLWIYQIFDSEKLDRAVKLPKIKINISDSA-SAENGWFVYNYTNAFSSSRYILGLRYLCRDSTDILREYVHRSDLVSTMKSVPSDSPKDLVVKEIDSNSALVSWKPLDQVHSNGIITHYEVRYYAPKKEESTERFINV------SETSAILSNLKYFHYVIYVRAFTKVGGGSWSNPKNYYRQNLEEFPIPTTIKGERKSETEINISWELPVLSEKNLAHAAIEGFIILYAPVESSPKWIKYTVQSKNLSA---VIKGLEPDLRYQFQIAATNYAGFNGNFSEIV---QEMPKNFPNLNLKTVPDLRCSVQSSNRLKVEWSSPSI 2886
++++T E D+ P I + Q V ++ + C+++G+P P ISW + P++ S + IK ++ L I ESD C A N+AG S L V P + P +V L C A G P P ++W K + TK + + G +L G Y C A ++ G+ + + + + + P P SLI+ + +V ++W SG + +++ YR SK E + +Y++ L P++ Y + + N +G PP+ + +T +P P + A +S T +LV W PPE G+ + Y++ YT++ F W++ +D ++ ++ L+ Y +RV +G GP S + +KT G +Q F+ + I L W P ++ K Y L W+ ++ K +F P ++ + LK + K L+A + G G+ T+ I+A T + +H+ + S+ I W PP+ S + YQ E +R ++ I ++S W Y + TD+ S + T + VP P+ + V I+S + VSWKP Q +G I Y+V Y + E + I + ++ + I L Y + V A+T G G+ S K PT I T + I W+ P K + + G+ + Y E YTV+ + + GL Y F++ A N AG +S+ + +++P ++P NLK V ++ K+ W P +
Sbjct: 119 SAKLTVLEEDQIPHGFPTIDMGPQLKVVERTRTATMLCAASGNPDPEISWFKDFLPVDINSSNGR----------IKQLRSGALQIENSEESDQGK-YECVAVNSAGTRYSAPANLYVRVRRVPPRFSIPPTNHEVMP-----GGSVNLTCVAVGAPMPYVKWMKG----EQELTKEEEMPIGRNVLELTNIRQSGNYTCVAISSLGM-IDTTAQITVKALPRPPASLIVTETTATSVTLTWDSGNPEPVSY--YVIQYR------------SKISDNGFQEVDGVASTRYSIGGLSPYSEYEFRVMAVNNIGRGPPSGMVETRTSEQAPSSPPLRVQARMLSATTMLVQWEPPEEPNGQIRGYRVYYTSDLHFPLSTWQKHNTEDSSLTTISGLVPDITYGLRVLAFTSVGDGPPSDILQVKTQQGVPAQPTGFEAEAELDTRIMLSWLWPVQDQITK---YELTYWE-----ADSDNKHHVIFDPAGSYAIDS--------LKPDTLYKFSLAARSEMGLGVYTQPIEARTAQSAPSAPPQEVHLISLSSSSIKVSWVAPPAASRHGSIVRYSLAYQAVSGEDQERH-EVKDIPADVSSYVLEGLEKWTEYT---------------VWVKAHTDVGPGPESGSTRIRTQEDVPGAPPRRVEVDNINSTALRVSWKPPLQQKQHGHIRGYQVVYSRLENGEPRGQPIILDVALPEAQEAVISGLLPETTYSVTVAAYTTKGDGARSKAKVVTTTGAVPGK-PTMIISTTIGNTAL-IQWQPP----KEMV-GELMGYRLRYKREEED----IYTVRDFRRTDDHFTVTGLHKGATYIFKLCAKNRAGNGEEYSKEISTPEDVPSSYPQ-NLKVV------GLTTTTTKLAWDPPPL 931 HSP 5 Score: 70.8626 bits (172), Expect = 1.921e-11 Identity = 131/594 (22.05%), Postives = 236/594 (39.73%), Query Frame = 1
Query: 1126 YNLKDLFPFTTYCIWMESENPLGVSPPTIALTVKTLPTSPQLSPRSITATSISNTAILVAW--RPPERKFGKFKYYQIIYTNNDGFLPQHWRQFAVKDDNVMLTHLIASEL-----YHIRVKIVNEIGHGPLSKTISIKTIAGTLSQCPD-FKITEIFQSHIKLQWGTPDPVKLFKLIQYNLLCWDVRLKIVNATAKSSTLFPILNHNLSMNEMEYVLYLKNEKEIKCRLSAINSDGKGMPTEIQASTVNKGV-NYQNLIHIDKIGSTYITFQWRPPSKFSFDYFLWIYQI-FDSEKLDRAVKLPKIKINISDSASAENGWFVYNYTNAFSSSRYILGLRYLCRDSTDILREYVHRSDLVSTMKSVPSDSPKDLVVKEIDSNSALVSWKPLDQVHSNGIITHYEVRYYAPKKEESTERFINVSETSAILSNLKY-FHYVIYVRAFTKVGGG--SWSNPKNYYRQNLEEFPIPTTIKGERKSETEINISWELPVLSEKNLAHAAIEGFIILYAPVESSPKWIKYTVQSKNLSAVIKGLEPDLRYQFQIAATNYAGFNGNFSEIVQEMPKNFPNLNLKTVPDLRCSVQSSNRLKVE 2868
Y + L P T Y + + + +G+ T + +T ++P P+ + S+S+++I V+W P + G Y + Y G + + VKD ++ + L Y + VK ++G GP S + I+T P ++ I + +++ W P K I+ + + ++ N + + IL+ L + + L E ++A + G G ++ + T V +I IG+T + QW+PP + + L Y++ + E+ D + D ++ + V T + YI L ++ EY S +ST + VPS P++L V + + + ++W P NG I Y V Y ++ ++T + LK Y I VRAFT GGG S S ++ EF +K K T + ++WE+P + + F ILY VQ +I L+PD Y F + + GN + +Q+ ++++T PDL + + +L E
Sbjct: 566 YAIDSLKPDTLYKFSLAARSEMGLGVYTQPIEARTAQSAPSAPPQEVHLISLSSSSIKVSWVAPPAASRHGSIVRYSLAYQAVSG---EDQERHEVKDIPADVSSYVLEGLEKWTEYTVWVKAHTDVGPGPESGSTRIRTQEDVPGAPPRRVEVDNINSTALRVSWKPPLQQKQHGHIRGYQVVYS---RLENGEPRGQPI--ILDVALPEAQEAVISGLLPETTYSVTVAAYTTKGDGARSKAKVVTTTGAVPGKPTMIISTTIGNTAL-IQWQPPKEMVGE--LMGYRLRYKREEED--------IYTVRDFRRTDDHFTV---TGLHKGATYIFKL--CAKNRAGNGEEY---SKEISTPEDVPSSYPQNLKVVGLTTTTTKLAWDPPPLPERNGKIVRYVVVYRDINSHQNQTN--GTADTEMTIQGLKPDTTYDIRVRAFTGKGGGPISPSIQSRTMSTSMPEFTKNFGVKAVMK--TSVLLTWEVPETYKSQVP------FKILY-------NQQSVEVQGDLKRKLITRLQPDTDYSFVLMS------RGNSAGGLQQ------QVSIRTAPDLFTTKPAHQKLDPE 1103
BLAST of Protein tyrosine phosphatase receptor type D vs. Ensembl Zebrafish
Match: ptprfa (protein tyrosine phosphatase receptor type Fa [Source:ZFIN;Acc:ZDB-GENE-020107-2]) HSP 1 Score: 720.309 bits (1858), Expect = 0.000e+0 Identity = 331/606 (54.62%), Postives = 440/606 (72.61%), Query Frame = 1
Query: 4006 SDSIKLRIGSQKSENISDRPSISICNLYQYVTDLKANDCTLLQAEFETLNTNLDDRFTWQRSNIDSNKSKNRYANVVAYDHTSVLLTPVDDVIGSDYINANYIDGYQRQNAYIATQGPLPDTTDDFWRMVWEQRSNCIVMMTRLEERSGIKCHQYWPNRGFICYGQMIVSHIDTFVLAYYTIRLFEIRHSKYSEKREIQHFQFTAWPDHGVPKLSTPLLMFIRRVRSIGKIESCPKIVHCSAGVGRTGAFIVVDAQLERIKQEKNIDVFNYVSKIRCQRNYMVQTQAQYQFILETLLEAVEDGNTEVMACNFHAHVTKLSQIGISGSNQLSGFEMEFSKLNSLASNRGRHGVMLADFVKAAGNQAVNMTKNRVRNIIPYEWNRVVLNAIRGIEGSDYINASYIDGYRDRRAYIAAQSPIPSTVEDFWRMLWDQHCGVVIVLNQPHE---DKSHIYWPINKSIRYQFFVVDPVVEYNMPNYILREFKVTDARDGEFRALRQFQFTQWPNHGCPKESESILDFIRQVHKTKEQFGHMEPMVIHCNTGSGRTGVFIALSIVLDRLQQESVVDMYQTVKLLHKQRIGLVQTEEQYEFCYMAVLDYLSNYE 5814
SD +++R + +++ + + P +S+C L ++ L+AND E+E+++ +FTW+ SN++ NK KNRYANV+AYDH+ V+LTPVD V GSDYIN NYIDGY++QNAYIATQGPLP+T DFWRMVWEQR++ IVMMTRLEE+S +KC QYWP+RG YG + VS +DT LA Y++R F + + SEKRE++ FQF AWPDHGVP+ TP+L F+RRV++ ++ P +VHCSAGVGRTG FIV+DA LER+K EK++D++ +V+ +R QRNYMVQT+ QY FI E LLEA GNTEV A + + H+ KL+Q + ++ E+EF KL + ++ R F+ A+ N KNR+ NI+P+E +RV L IRG+EGSDYINAS+IDGYR ++AYIA Q P+ T EDFWRMLW+ + +V++L + E +K H YWP +S RYQ+FVVDP+ EYNMP YILREFKVTDARDG+ R +RQFQFT WP G PK E +DFI QVHKTKEQFG P+ +HC+ G GRTGVFI LSIVL+R++ E VVDM+QT+K L QR +VQTE+QY+ CY A L+YL +++
Sbjct: 1297 SDPVEMRRLNYQTQGMREHPPVSVCALADHIERLRANDSLRFSQEYESVDPG--QQFTWENSNLEVNKPKNRYANVIAYDHSRVVLTPVDGVPGSDYINGNYIDGYRKQNAYIATQGPLPETLSDFWRMVWEQRTSTIVMMTRLEEKSRVKCDQYWPSRGTETYGMIQVSMLDTVELATYSVRTFALYKNGSSEKREVRQFQFMAWPDHGVPEYPTPILAFLRRVKACNPPDAGPMVVHCSAGVGRTGCFIVIDAMLERMKHEKSVDIYGHVTCMRSQRNYMVQTEDQYIFIHEALLEAATCGNTEVPARSLYTHIQKLTQ--APPGDTVTAMELEFKKLANSKAHTSR-------FISAS--LPCNKFKNRLVNIMPFESSRVCLQPIRGVEGSDYINASFIDGYRQQKAYIATQGPLSETTEDFWRMLWEHNSTIVVMLTKLREMGREKCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDARDGQSRTIRQFQFTDWPEQGVPKTGEGFIDFIGQVHKTKEQFGQDGPITVHCSAGVGRTGVFITLSIVLERMRYEGVVDMFQTIKTLRTQRPAMVQTEDQYQLCYRAALEYLGSFD 1889 HSP 2 Score: 202.601 bits (514), Expect = 1.664e-51 Identity = 103/263 (39.16%), Postives = 150/263 (57.03%), Query Frame = 1
Query: 5092 NQAVNMTKNRVRNIIPYEWNRVVLNAIRGIEGSDYINASYIDGYRDRRAYIAAQSPIPSTVEDFWRMLWDQHCGVVIVLNQPHEDKSHI----YWPINKSIRYQFFVVDPVVEYNMPNYILREFKVTDARDGEFRALRQFQFTQWPNHGCPKESESILDFIRQVHKTKEQFGHMEPMVIHCNTGSGRTGVFIALSIVLDRLQQESVVDMYQTVKLLHKQRIGLVQTEEQYEFCYMAVLDYLSNYEKILEKSHLY*TYQDLSES 5868
N VN KNR N+I Y+ +RVVL + G+ GSDYIN +YIDGYR + AYIA Q P+P T+ DFWRM+W+Q ++++ + E+KS + YWP + Y V + + Y +R F + E R +RQFQF WP+HG P+ IL F+R+V PMV+HC+ G GRTG FI + +L+R++ E VD+Y V + QR +VQTE+QY F + A+L+ + + LY Q L+++
Sbjct: 1357 NLEVNKPKNRYANVIAYDHSRVVLTPVDGVPGSDYINGNYIDGYRKQNAYIATQGPLPETLSDFWRMVWEQRTSTIVMMTR-LEEKSRVKCDQYWPSRGTETYGMIQVSMLDTVELATYSVRTFALYKNGSSEKREVRQFQFMAWPDHGVPEYPTPILAFLRRVKACNPP--DAGPMVVHCSAGVGRTGCFIVIDAMLERMKHEKSVDIYGHVTCMRSQRNYMVQTEDQYIFIHEALLEAATCGNTEVPARSLYTHIQKLTQA 1616 HSP 3 Score: 150.984 bits (380), Expect = 7.655e-36 Identity = 231/1011 (22.85%), Postives = 377/1011 (37.29%), Query Frame = 1
Query: 370 LACSSTGHPVPSISWKINESPIEELKSPLKKLQNPPRIFSIKNYQNSVLVITQLIESDSNSVLICEAENNAGFDSRQQQLKVISTETDIPSGFPVFQNNFFPIIKPYNSNVTLVCQAYGNPPPLIQWFKNYEL--INESFTKIKILNDGNLLLVQVTREDKGIYHCQAQNTNGLRLSDPSTLDI------TSYPISPNSLIIERFASDNVE----------ISWRSGLNDVTEQENFILHYREVPENITEKQIMSKFVYLTISEKKSIYKYNLKDLFPFTTYCIWMESENPLGVSPPTIALTVKTLPTSPQLSPRSITATSISNTAILVAWRP--PERKFGKFKYYQIIY---TNNDGFLPQHWRQFAVKDDNVMLTHLIASELYHIRVKIVNEIGHGPLSKTISIKTIAGTLSQCP-DFKITEIFQSHIKLQWGTPDPVKLFKLIQYNLLCWDVRLKIVNATAKSSTLFPI---LNHNLSMNEMEYVLYLKNEKEIKCRLSAINSDGKGMPTEIQASTVNKGVNYQNL-IHIDKIGSTYITFQWRPPSKFSFDYFLWIYQIFDSEKLDRAVKLPKIKINISDSASAENGWFVYNYTNAFSSSRYILGLRYLCRDSTDILREYVHRSDLVSTMKSVPSDSPKDLVVKEIDSNSALVSWKPLDQVHSNGIITHYEVRYYAPKKEESTE---RFINVSETSAILSNL-KYFHYVIYVRAFTKVGGGSWSNPKNYYRQNLEEFPIPTTIKGERKSETEINISWELPVLSEKNLAHAAIEGFIILYAPVESS-PKW---IKYTVQSKNLSAVIKGLEPDLRYQFQIAATNYAGFNGNFSEIVQEMPKNFPNLNLKTVPDLRCSVQSSNRLKVEWSSP-SISTDLLKFEIRYSGNLSYITEIGLKKSEFIDMESKSVNFETLVNRYDVTLENLQSNALYKIAVRAIYQNKELYESHRETTCDTMPAVPNLVKPPIIVGLDEEKSKVIIKLHRCSQRNGKISYYFVIVAAFQGNKNQ 3291
C + G P P I+W +K K + + SVL I L ++ C A N+ G + +L V+ E IP GFP + T++C A GNP P I WFK++ IN S +IK L G L + D+G Y C A N+ G R S P+ L + + I P + + S N+ + W G ++T++E E I + LT N++ +T C+ + S LG+ T +TVK LP P S+ T + T++ + W PE YY I Y +++GF V + L Y RV VN IG GP S + +T S P + + + + +QW P+ + +++ S FP+ HN + + + L + R+ A S G G P++I +GV Q + T I W P + + Y DS+ + P I DS + +Y ++ A +R +GL + T +S PS P+++ + + S+S VSW +G I Y + Y A E+ + I +S +L L K+ Y ++V+A T VG G S Q P ++ + + T + +SW+ P+ ++ H I G+ ++Y+ +E+ P+ I + AVI GL P+ Y +AA G V P P + S N ++W P + +L+ + +RY K E D+ + +F + + VT + + ++K+ + N E Y T D + P +K +VGL +K+ +RNGKI Y V+ ++NQ
Sbjct: 52 FVCQAVGEPKPRITW---------MKKGKKVSSQRFEVIEFDDGSGSVLRIQPLRTHRDEAIYECTATNSVGEINTSAKLTVLE-EDQIPHGFPTIDMGPQLKVVERTRTATMLCAASGNPDPEISWFKDFLPVDINSSNGRIKQLRSGALQIENSEESDQGKYECVAVNSAGTRYSAPANLYVRVRRVPPRFSIPPTNHEVMPGGSVNLTCVAVGAPMPYVKWMKGEQELTKEE--------------EMPIGRNVLELT----------NIRQSGNYT--CVAISS---LGMIDTTAQITVKALPRPPA----SLIVTETTATSVTLTWDSGNPE----PVSYYVIQYRSKISDNGFQ----EVDGVASTRYSIGGLSPYSEYEFRVMAVNNIGRGPPSGMVETRTSEQAPSSPPLRVQARMLSATTMLVQWEPPEEP-------------NGQIRGYRVYYTSDLHFPLSTWQKHNTEDSSLTTISGLVPDITYGLRVLAFTSVGDGPPSDILQVKTQQGVPAQPTGFEAEAELDTRIMLSWLWPVQDQITKYELTYWEADSDNKHHVIFDPAGSYAI-DSLKPDT---LYKFSLA---ARSEMGLGVYTQPIE------------ARTAQSAPSAPPQEVHLISLSSSSIKVSWVAPPAASRHGSIVRYSLAYQAVSGEDQERHEVKDIPADVSSYVLEGLEKWTEYTVWVKAHTDVGPGPESGSTRIRTQEDVPGAPPRRVEVDNINSTALRVSWKPPLQQKQ---HGHIRGYQVVYSRLENGEPRGQPIILDVALPEAQEAVISGLLPETTYSVTVAAYTTKGDGARSKAKVVTTTGAVPGK-----PTMIISTTIGNTALIQWQPPKEMVGELMGYRLRY-------------KREEEDIYTVR-DFRRTDDHFTVTGLHKGATYIFKLCAKNRAGNGEEYSKEISTPEDVPSSYPQNLK---VVGLTTTTTKLAWDPPPLPERNGKIVRYVVVYRDINSHQNQ 954 HSP 4 Score: 140.969 bits (354), Expect = 1.056e-32 Identity = 207/898 (23.05%), Postives = 358/898 (39.87%), Query Frame = 1
Query: 277 NSQITFTENDEAP----KISLIIQSPNVLLFKSMILACSSTGHPVPSISWKINESPIEELKSPLKKLQNPPRIFSIKNYQNSVLVITQLIESDSNSVLICEAENNAGFD-SRQQQLKVISTETDIPSGFPVFQNNFFPIIKPYNSNVTLVCQAYGNPPPLIQWFKNYELINESFTKIKILNDGNLLLVQVTREDKGIYHCQAQNTNGLRLSDPSTLDITSYPISPNSLIIERFASDNVEISWRSGLNDVTEQENFILHYREVPENITEKQIMSKFVYLTISEKKSIY--KYNLKDLFPFTTYCIWMESENPLGVSPPTIALTVKTLPTSPQLSPRSITATSISNTAILVAWRPPERKFGKFKYYQIIYTNNDGFLPQHWRQFAVKDDNV-MLTHLIASELYHIRVKIVNEIGHGPLSKTISIKTIAGTLSQCPDFKITEIFQSHIKLQWGTPDPVKLFKLIQYNLLCWDVRLKIVNATAKSSTLF-PILNHNLSMNEMEYVLYLKNEKEIKCRLSAINSDGKGMPTE-IQASTVNKGVNY-QNLIHIDKIGSTYITFQW-RPPSK---FSFDYFLWIYQIFDSEKLDRAVKLPKIKINISDSA-SAENGWFVYNYTNAFSSSRYILGLRYLCRDSTDILREYVHRSDLVSTMKSVPSDSPKDLVVKEIDSNSALVSWKPLDQVHSNGIITHYEVRYYAPKKEESTERFINV------SETSAILSNLKYFHYVIYVRAFTKVGGGSWSNPKNYYRQNLEEFPIPTTIKGERKSETEINISWELPVLSEKNLAHAAIEGFIILYAPVESSPKWIKYTVQSKNLSA---VIKGLEPDLRYQFQIAATNYAGFNGNFSEIV---QEMPKNFPNLNLKTVPDLRCSVQSSNRLKVEWSSPSI 2886
++++T E D+ P I + Q V ++ + C+++G+P P ISW + P++ S + IK ++ L I ESD C A N+AG S L V P + P +V L C A G P P ++W K + TK + + G +L G Y C A ++ G+ + + + + + P P SLI+ + +V ++W SG + +++ YR SK E + +Y++ L P++ Y + + N +G PP+ + +T +P P + A +S T +LV W PPE G+ + Y++ YT++ F W++ +D ++ ++ L+ Y +RV +G GP S + +KT G +Q F+ + I L W P ++ K Y L W+ ++ K +F P ++ + LK + K L+A + G G+ T+ I+A T + +H+ + S+ I W PP+ S + YQ E +R ++ I ++S W Y + TD+ S + T + VP P+ + V I+S + VSWKP Q +G I Y+V Y + E + I + ++ + I L Y + V A+T G G+ S K PT I T + I W+ P K + + G+ + Y E YTV+ + + GL Y F++ A N AG +S+ + +++P ++P NLK V ++ K+ W P +
Sbjct: 119 SAKLTVLEEDQIPHGFPTIDMGPQLKVVERTRTATMLCAASGNPDPEISWFKDFLPVDINSSNGR----------IKQLRSGALQIENSEESDQGK-YECVAVNSAGTRYSAPANLYVRVRRVPPRFSIPPTNHEVMP-----GGSVNLTCVAVGAPMPYVKWMKG----EQELTKEEEMPIGRNVLELTNIRQSGNYTCVAISSLGM-IDTTAQITVKALPRPPASLIVTETTATSVTLTWDSGNPEPVSY--YVIQYR------------SKISDNGFQEVDGVASTRYSIGGLSPYSEYEFRVMAVNNIGRGPPSGMVETRTSEQAPSSPPLRVQARMLSATTMLVQWEPPEEPNGQIRGYRVYYTSDLHFPLSTWQKHNTEDSSLTTISGLVPDITYGLRVLAFTSVGDGPPSDILQVKTQQGVPAQPTGFEAEAELDTRIMLSWLWPVQDQITK---YELTYWE-----ADSDNKHHVIFDPAGSYAIDS--------LKPDTLYKFSLAARSEMGLGVYTQPIEARTAQSAPSAPPQEVHLISLSSSSIKVSWVAPPAASRHGSIVRYSLAYQAVSGEDQERH-EVKDIPADVSSYVLEGLEKWTEYT---------------VWVKAHTDVGPGPESGSTRIRTQEDVPGAPPRRVEVDNINSTALRVSWKPPLQQKQHGHIRGYQVVYSRLENGEPRGQPIILDVALPEAQEAVISGLLPETTYSVTVAAYTTKGDGARSKAKVVTTTGAVPGK-PTMIISTTIGNTAL-IQWQPP----KEMV-GELMGYRLRYKREEED----IYTVRDFRRTDDHFTVTGLHKGATYIFKLCAKNRAGNGEEYSKEISTPEDVPSSYPQ-NLKVV------GLTTTTTKLAWDPPPL 931 HSP 5 Score: 70.8626 bits (172), Expect = 1.921e-11 Identity = 131/594 (22.05%), Postives = 236/594 (39.73%), Query Frame = 1
Query: 1126 YNLKDLFPFTTYCIWMESENPLGVSPPTIALTVKTLPTSPQLSPRSITATSISNTAILVAW--RPPERKFGKFKYYQIIYTNNDGFLPQHWRQFAVKDDNVMLTHLIASEL-----YHIRVKIVNEIGHGPLSKTISIKTIAGTLSQCPD-FKITEIFQSHIKLQWGTPDPVKLFKLIQYNLLCWDVRLKIVNATAKSSTLFPILNHNLSMNEMEYVLYLKNEKEIKCRLSAINSDGKGMPTEIQASTVNKGV-NYQNLIHIDKIGSTYITFQWRPPSKFSFDYFLWIYQI-FDSEKLDRAVKLPKIKINISDSASAENGWFVYNYTNAFSSSRYILGLRYLCRDSTDILREYVHRSDLVSTMKSVPSDSPKDLVVKEIDSNSALVSWKPLDQVHSNGIITHYEVRYYAPKKEESTERFINVSETSAILSNLKY-FHYVIYVRAFTKVGGG--SWSNPKNYYRQNLEEFPIPTTIKGERKSETEINISWELPVLSEKNLAHAAIEGFIILYAPVESSPKWIKYTVQSKNLSAVIKGLEPDLRYQFQIAATNYAGFNGNFSEIVQEMPKNFPNLNLKTVPDLRCSVQSSNRLKVE 2868
Y + L P T Y + + + +G+ T + +T ++P P+ + S+S+++I V+W P + G Y + Y G + + VKD ++ + L Y + VK ++G GP S + I+T P ++ I + +++ W P K I+ + + ++ N + + IL+ L + + L E ++A + G G ++ + T V +I IG+T + QW+PP + + L Y++ + E+ D + D ++ + V T + YI L ++ EY S +ST + VPS P++L V + + + ++W P NG I Y V Y ++ ++T + LK Y I VRAFT GGG S S ++ EF +K K T + ++WE+P + + F ILY VQ +I L+PD Y F + + GN + +Q+ ++++T PDL + + +L E
Sbjct: 566 YAIDSLKPDTLYKFSLAARSEMGLGVYTQPIEARTAQSAPSAPPQEVHLISLSSSSIKVSWVAPPAASRHGSIVRYSLAYQAVSG---EDQERHEVKDIPADVSSYVLEGLEKWTEYTVWVKAHTDVGPGPESGSTRIRTQEDVPGAPPRRVEVDNINSTALRVSWKPPLQQKQHGHIRGYQVVYS---RLENGEPRGQPI--ILDVALPEAQEAVISGLLPETTYSVTVAAYTTKGDGARSKAKVVTTTGAVPGKPTMIISTTIGNTAL-IQWQPPKEMVGE--LMGYRLRYKREEED--------IYTVRDFRRTDDHFTV---TGLHKGATYIFKL--CAKNRAGNGEEY---SKEISTPEDVPSSYPQNLKVVGLTTTTTKLAWDPPPLPERNGKIVRYVVVYRDINSHQNQTN--GTADTEMTIQGLKPDTTYDIRVRAFTGKGGGPISPSIQSRTMSTSMPEFTKNFGVKAVMK--TSVLLTWEVPETYKSQVP------FKILY-------NQQSVEVQGDLKRKLITRLQPDTDYSFVLMS------RGNSAGGLQQ------QVSIRTAPDLFTTKPAHQKLDPE 1103
BLAST of Protein tyrosine phosphatase receptor type D vs. Ensembl Zebrafish
Match: ptprfa (protein tyrosine phosphatase receptor type Fa [Source:ZFIN;Acc:ZDB-GENE-020107-2]) HSP 1 Score: 720.309 bits (1858), Expect = 0.000e+0 Identity = 331/606 (54.62%), Postives = 440/606 (72.61%), Query Frame = 1
Query: 4006 SDSIKLRIGSQKSENISDRPSISICNLYQYVTDLKANDCTLLQAEFETLNTNLDDRFTWQRSNIDSNKSKNRYANVVAYDHTSVLLTPVDDVIGSDYINANYIDGYQRQNAYIATQGPLPDTTDDFWRMVWEQRSNCIVMMTRLEERSGIKCHQYWPNRGFICYGQMIVSHIDTFVLAYYTIRLFEIRHSKYSEKREIQHFQFTAWPDHGVPKLSTPLLMFIRRVRSIGKIESCPKIVHCSAGVGRTGAFIVVDAQLERIKQEKNIDVFNYVSKIRCQRNYMVQTQAQYQFILETLLEAVEDGNTEVMACNFHAHVTKLSQIGISGSNQLSGFEMEFSKLNSLASNRGRHGVMLADFVKAAGNQAVNMTKNRVRNIIPYEWNRVVLNAIRGIEGSDYINASYIDGYRDRRAYIAAQSPIPSTVEDFWRMLWDQHCGVVIVLNQPHE---DKSHIYWPINKSIRYQFFVVDPVVEYNMPNYILREFKVTDARDGEFRALRQFQFTQWPNHGCPKESESILDFIRQVHKTKEQFGHMEPMVIHCNTGSGRTGVFIALSIVLDRLQQESVVDMYQTVKLLHKQRIGLVQTEEQYEFCYMAVLDYLSNYE 5814
SD +++R + +++ + + P +S+C L ++ L+AND E+E+++ +FTW+ SN++ NK KNRYANV+AYDH+ V+LTPVD V GSDYIN NYIDGY++QNAYIATQGPLP+T DFWRMVWEQR++ IVMMTRLEE+S +KC QYWP+RG YG + VS +DT LA Y++R F + + SEKRE++ FQF AWPDHGVP+ TP+L F+RRV++ ++ P +VHCSAGVGRTG FIV+DA LER+K EK++D++ +V+ +R QRNYMVQT+ QY FI E LLEA GNTEV A + + H+ KL+Q + ++ E+EF KL + ++ R F+ A+ N KNR+ NI+P+E +RV L IRG+EGSDYINAS+IDGYR ++AYIA Q P+ T EDFWRMLW+ + +V++L + E +K H YWP +S RYQ+FVVDP+ EYNMP YILREFKVTDARDG+ R +RQFQFT WP G PK E +DFI QVHKTKEQFG P+ +HC+ G GRTGVFI LSIVL+R++ E VVDM+QT+K L QR +VQTE+QY+ CY A L+YL +++
Sbjct: 1195 SDPVEMRRLNYQTQGMREHPPVSVCALADHIERLRANDSLRFSQEYESVDPG--QQFTWENSNLEVNKPKNRYANVIAYDHSRVVLTPVDGVPGSDYINGNYIDGYRKQNAYIATQGPLPETLSDFWRMVWEQRTSTIVMMTRLEEKSRVKCDQYWPSRGTETYGMIQVSMLDTVELATYSVRTFALYKNGSSEKREVRQFQFMAWPDHGVPEYPTPILAFLRRVKACNPPDAGPMVVHCSAGVGRTGCFIVIDAMLERMKHEKSVDIYGHVTCMRSQRNYMVQTEDQYIFIHEALLEAATCGNTEVPARSLYTHIQKLTQ--APPGDTVTAMELEFKKLANSKAHTSR-------FISAS--LPCNKFKNRLVNIMPFESSRVCLQPIRGVEGSDYINASFIDGYRQQKAYIATQGPLSETTEDFWRMLWEHNSTIVVMLTKLREMGREKCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDARDGQSRTIRQFQFTDWPEQGVPKTGEGFIDFIGQVHKTKEQFGQDGPITVHCSAGVGRTGVFITLSIVLERMRYEGVVDMFQTIKTLRTQRPAMVQTEDQYQLCYRAALEYLGSFD 1787 HSP 2 Score: 202.601 bits (514), Expect = 1.373e-51 Identity = 103/263 (39.16%), Postives = 150/263 (57.03%), Query Frame = 1
Query: 5092 NQAVNMTKNRVRNIIPYEWNRVVLNAIRGIEGSDYINASYIDGYRDRRAYIAAQSPIPSTVEDFWRMLWDQHCGVVIVLNQPHEDKSHI----YWPINKSIRYQFFVVDPVVEYNMPNYILREFKVTDARDGEFRALRQFQFTQWPNHGCPKESESILDFIRQVHKTKEQFGHMEPMVIHCNTGSGRTGVFIALSIVLDRLQQESVVDMYQTVKLLHKQRIGLVQTEEQYEFCYMAVLDYLSNYEKILEKSHLY*TYQDLSES 5868
N VN KNR N+I Y+ +RVVL + G+ GSDYIN +YIDGYR + AYIA Q P+P T+ DFWRM+W+Q ++++ + E+KS + YWP + Y V + + Y +R F + E R +RQFQF WP+HG P+ IL F+R+V PMV+HC+ G GRTG FI + +L+R++ E VD+Y V + QR +VQTE+QY F + A+L+ + + LY Q L+++
Sbjct: 1255 NLEVNKPKNRYANVIAYDHSRVVLTPVDGVPGSDYINGNYIDGYRKQNAYIATQGPLPETLSDFWRMVWEQRTSTIVMMTR-LEEKSRVKCDQYWPSRGTETYGMIQVSMLDTVELATYSVRTFALYKNGSSEKREVRQFQFMAWPDHGVPEYPTPILAFLRRVKACNPP--DAGPMVVHCSAGVGRTGCFIVIDAMLERMKHEKSVDIYGHVTCMRSQRNYMVQTEDQYIFIHEALLEAATCGNTEVPARSLYTHIQKLTQA 1514 HSP 3 Score: 157.918 bits (398), Expect = 7.008e-38 Identity = 250/1151 (21.72%), Postives = 447/1151 (38.84%), Query Frame = 1
Query: 277 NSQITFTENDEAP----KISLIIQSPNVLLFKSMILACSSTGHPVPSISWKINESPIEELKSPLKKLQNPPRIFSIKNYQNSVLVITQLIESDSNSVLICEAENNAGFD-SRQQQLKVISTETDIPSGFPVFQNNFFPIIKPYNSNVTLVCQAYGNPPPLIQWFKNYELINESFTKIKILNDGNLLLVQVTREDKGIYHCQAQNTNGLRLSDPSTLDITSYPISPNSLIIERFASDNVEISWRSGLNDVTEQENFILHYREVPENITEKQIMSKFVYLTISEKKSIY--KYNLKDLFPFTTYCIWMESENPLGVSPPTIALTVKTLPTSPQLSPRSITATSISNTAILVAWRPPERKFGKFKYYQIIYTNNDGFLPQHWRQFAVKDDNV-MLTHLIASELYHIRVKIVNEIGHGPLSKTISIKTIAGTLSQCPDFKITEIFQSHIKLQWGTPDPVKLFKLIQYNLLCWDVRLKIVNATAKSSTLF-PILNHNLSMNEMEYVLYLKNEKEIKCRLSAINSDGKGM---PTEIQASTVNKGVNYQNLIHIDKIGSTYITFQWRPPSKFSFDYFLWIYQIFDSEKLDRA----------VKLPKIKINISDSASAENGW--FVYNYTNAFSSSRYILGLRYLCRDSTDILREYVHRSDLVSTMKSVPSDSPKDLVVKEIDSNSALVSWKPLDQVHSNGIITHYEVRYYAPKKEESTERFINVSETSAILSNL-KYFHYVIYVRAFTKVGGG-----SWSNPKNY---YRQNLEEFPIPTTIKGERKSETEINISWELPVLSEKNLAHAAIEGFIILYAPVESSPKWIKYTVQSKNLSAVIKGLEPDLRYQFQIAATNYAGFNGNFSEIVQ------EMPKNFPNLNLKTVPDLRCSVQSSNRLKVEWSSPSISTDLLKFEIRYSGNLSYITEIGLKKSEFIDMESKSVNFETLVNRYDVTLENLQSNALYKIAVRAIYQNKELYESHRETTCDTMPAVPNLVKPPIIVGLD-EEKSKVIIKLHRCSQRNGKISYYFVIVAAFQGNKNQQISFQEDTESYTFMELSVNTRSNNAKGEYIAIMKDINDIFK--VSGKDHS---SVLLGDGTHDENHLSVNKKLEKNFNYRCFARVCLKYSNNSLCKSSPWSEPFRI 3594
++++T E D+ P I + Q V ++ + C+++G+P P ISW + P++ S + IK ++ L I ESD C A N+AG S L V P + P +V L C A G P P ++W K + TK + + G +L G Y C A ++ G+ + + + + + P P SLI+ + +V ++W SG + +++ YR SK E + +Y++ L P++ Y + + N +G PP+ + +T +P P + A +S T +LV W PPE G+ + Y++ YT++ F W++ +D ++ ++ L+ Y +RV +G GP S + +KT G +Q F+ + I L W P ++ K Y L W+ ++ K +F P ++ + LK + K L+A + G G+ P E + + G + + +D I ST + W+PP + + YQ+ S +L+ V LP+ + + E + V YT +R ++ +V+T +VP +++ N+AL+ W+P ++ G + Y +RY +++ T R ++ ++ L K Y+ + A + G G S P++ Y QNL+ + TT ++W+ P L E+N I ++++Y + S T ++ I+GL+PD Y ++ A G G S +Q MP+ N +K V ++ SV + W P + F+I Y+ +SV + + R +T LQ + Y + + + ++ + T P + P LD EE K+ I L + + +++++V + + ED + M NN + D + ++ K S +LGD N+ NK L YR F LK +S SP+SEP +
Sbjct: 119 SAKLTVLEEDQIPHGFPTIDMGPQLKVVERTRTATMLCAASGNPDPEISWFKDFLPVDINSSNGR----------IKQLRSGALQIENSEESDQGK-YECVAVNSAGTRYSAPANLYVRVRRVPPRFSIPPTNHEVMP-----GGSVNLTCVAVGAPMPYVKWMKG----EQELTKEEEMPIGRNVLELTNIRQSGNYTCVAISSLGM-IDTTAQITVKALPRPPASLIVTETTATSVTLTWDSGNPEPVSY--YVIQYR------------SKISDNGFQEVDGVASTRYSIGGLSPYSEYEFRVMAVNNIGRGPPSGMVETRTSEQAPSSPPLRVQARMLSATTMLVQWEPPEEPNGQIRGYRVYYTSDLHFPLSTWQKHNTEDSSLTTISGLVPDITYGLRVLAFTSVGDGPPSDILQVKTQQGVPAQPTGFEAEAELDTRIMLSWLWPVQDQITK---YELTYWE-----ADSDNKHHVIFDPAGSYAIDS--------LKPDTLYKFSLAARSEMGLGVYTQPIEARTAQSVPGAPPRR-VEVDNINSTALRVSWKPPLQQKQHGHIRGYQVVYS-RLENGEPRGQPIILDVALPEAQEAVISGLLPETTYSVTVAAYTTKGDGAR--------------------SKAKVVTTTGAVPGKP--TMIISTTIGNTALIQWQPPKEM--VGELMGYRLRYKREEEDIYTVRDFRRTDDHFTVTGLHKGATYIFKLCAKNRAGNGEEYSKEISTPEDVPSSYPQNLKVVGLTTTT---------TKLAWDPPPLPERN---GKIVRYVVVYRDINSHQNQTNGTADTE---MTIQGLKPDTTYDIRVRAFTGKG-GGPISPSIQSRTMSTSMPEFTKNFGVKAV--MKTSVL------LTWEVPETYKSQVPFKILYN--------------------QQSVEVQGDLKRKLIT--RLQPDTDYSFVL--MSRGNSAGGLQQQVSIRTAPDL--FTTKPAHQKLDPEEGGKLAITLPEV-HNSALVRWFYIVVVPVTPSTLRHWENPEDIDLDELM-------GNNRDAAVRRRRRQTQDFLRPYIAAKLESLPERFVLGDEKTYSNYY--NKPLPGQQQYRTFILAALK-DRDSTFTVSPFSEPMMV 1131 HSP 4 Score: 121.324 bits (303), Expect = 9.433e-27 Identity = 205/879 (23.32%), Postives = 325/879 (36.97%), Query Frame = 1
Query: 370 LACSSTGHPVPSISWKINESPIEELKSPLKKLQNPPRIFSIKNYQNSVLVITQLIESDSNSVLICEAENNAGFDSRQQQLKVISTETDIPSGFPVFQNNFFPIIKPYNSNVTLVCQAYGNPPPLIQWFKNYEL--INESFTKIKILNDGNLLLVQVTREDKGIYHCQAQNTNGLRLSDPSTLDI------TSYPISPNSLIIERFASDNVE----------ISWRSGLNDVTEQENFILHYREVPENITEKQIMSKFVYLTISEKKSIYKYNLKDLFPFTTYCIWMESENPLGVSPPTIALTVKTLPTSPQLSPRSITATSISNTAILVAWRP--PERKFGKFKYYQIIY---TNNDGFLPQHWRQFAVKDDNVMLTHLIASELYHIRVKIVNEIGHGPLSKTISIKTIAGTLSQCP-DFKITEIFQSHIKLQWGTPDPVKLFKLIQYNLLCWDVRLKIVNATAKSSTLFPI---LNHNLSMNEMEYVLYLKNEKEIKCRLSAINSDGKGMPTEIQASTVNKGVNYQNL-IHIDKIGSTYITFQWRPPSKFSFDYFLWIYQIFDSEKLDRAVKLPKIKINISDSASAENGWFVYNYTNAFSSSRYILGLRYLCRDSTDILREYVHRSDLVSTMKSVPSDSPKDLVVKEIDSNSALVSWKPLDQVHSNGIITHYEVRYYAPKKEESTERFINV------SETSAILSNLKYFHYVIYVRAFTKVGGGSWSNPKNYYRQNLEEFPIPTTIKGERKSETEINISWELPVLSEKNLAHAAIEGFIILYAPVESSPKWIKYTVQSKNLSA---VIKGLEPDLRYQFQIAATNYAGFNGNFSEIV---QEMPKNFPNLNLKTVPDLRCSVQSSNRLKVEWSSPSI 2886
C + G P P I+W +K K + + SVL I L ++ C A N+ G + +L V+ E IP GFP + T++C A GNP P I WFK++ IN S +IK L G L + D+G Y C A N+ G R S P+ L + + I P + + S N+ + W G ++T++E E I + LT N++ +T C+ + S LG+ T +TVK LP P S+ T + T++ + W PE YY I Y +++GF V + L Y RV VN IG GP S + +T S P + + + + +QW P+ + +++ S FP+ HN + + + L + R+ A S G G P++I +GV Q + T I W P + + Y DS+ + P I DS + +Y ++ A +R +GL + T +SVP P+ + V I+S + VSWKP Q +G I Y+V Y + E + I + ++ + I L Y + V A+T G G+ S K PT I T + I W+ P K + + G+ + Y E YTV+ + + GL Y F++ A N AG +S+ + +++P ++P NLK V ++ K+ W P +
Sbjct: 52 FVCQAVGEPKPRITW---------MKKGKKVSSQRFEVIEFDDGSGSVLRIQPLRTHRDEAIYECTATNSVGEINTSAKLTVLE-EDQIPHGFPTIDMGPQLKVVERTRTATMLCAASGNPDPEISWFKDFLPVDINSSNGRIKQLRSGALQIENSEESDQGKYECVAVNSAGTRYSAPANLYVRVRRVPPRFSIPPTNHEVMPGGSVNLTCVAVGAPMPYVKWMKGEQELTKEE--------------EMPIGRNVLELT----------NIRQSGNYT--CVAISS---LGMIDTTAQITVKALPRPPA----SLIVTETTATSVTLTWDSGNPE----PVSYYVIQYRSKISDNGFQEVD----GVASTRYSIGGLSPYSEYEFRVMAVNNIGRGPPSGMVETRTSEQAPSSPPLRVQARMLSATTMLVQWEPPEEP-------------NGQIRGYRVYYTSDLHFPLSTWQKHNTEDSSLTTISGLVPDITYGLRVLAFTSVGDGPPSDILQVKTQQGVPAQPTGFEAEAELDTRIMLSWLWPVQDQITKYELTYWEADSDNKHHVIFDPAGSYAI-DSLKPDT---LYKFSLA---ARSEMGLGVYTQPIE------------ARTAQSVPGAPPRRVEVDNINSTALRVSWKPPLQQKQHGHIRGYQVVYSRLENGEPRGQPIILDVALPEAQEAVISGLLPETTYSVTVAAYTTKGDGARSKAKVVTTTGAVPGK-PTMIISTTIGNTAL-IQWQPP----KEMV-GELMGYRLRYKREEED----IYTVRDFRRTDDHFTVTGLHKGATYIFKLCAKNRAGNGEEYSKEISTPEDVPSSYPQ-NLKVV------GLTTTTTKLAWDPPPL 829
BLAST of Protein tyrosine phosphatase receptor type D vs. Ensembl Zebrafish
Match: ptprfa (protein tyrosine phosphatase receptor type Fa [Source:ZFIN;Acc:ZDB-GENE-020107-2]) HSP 1 Score: 720.309 bits (1858), Expect = 0.000e+0 Identity = 331/606 (54.62%), Postives = 440/606 (72.61%), Query Frame = 1
Query: 4006 SDSIKLRIGSQKSENISDRPSISICNLYQYVTDLKANDCTLLQAEFETLNTNLDDRFTWQRSNIDSNKSKNRYANVVAYDHTSVLLTPVDDVIGSDYINANYIDGYQRQNAYIATQGPLPDTTDDFWRMVWEQRSNCIVMMTRLEERSGIKCHQYWPNRGFICYGQMIVSHIDTFVLAYYTIRLFEIRHSKYSEKREIQHFQFTAWPDHGVPKLSTPLLMFIRRVRSIGKIESCPKIVHCSAGVGRTGAFIVVDAQLERIKQEKNIDVFNYVSKIRCQRNYMVQTQAQYQFILETLLEAVEDGNTEVMACNFHAHVTKLSQIGISGSNQLSGFEMEFSKLNSLASNRGRHGVMLADFVKAAGNQAVNMTKNRVRNIIPYEWNRVVLNAIRGIEGSDYINASYIDGYRDRRAYIAAQSPIPSTVEDFWRMLWDQHCGVVIVLNQPHE---DKSHIYWPINKSIRYQFFVVDPVVEYNMPNYILREFKVTDARDGEFRALRQFQFTQWPNHGCPKESESILDFIRQVHKTKEQFGHMEPMVIHCNTGSGRTGVFIALSIVLDRLQQESVVDMYQTVKLLHKQRIGLVQTEEQYEFCYMAVLDYLSNYE 5814
SD +++R + +++ + + P +S+C L ++ L+AND E+E+++ +FTW+ SN++ NK KNRYANV+AYDH+ V+LTPVD V GSDYIN NYIDGY++QNAYIATQGPLP+T DFWRMVWEQR++ IVMMTRLEE+S +KC QYWP+RG YG + VS +DT LA Y++R F + + SEKRE++ FQF AWPDHGVP+ TP+L F+RRV++ ++ P +VHCSAGVGRTG FIV+DA LER+K EK++D++ +V+ +R QRNYMVQT+ QY FI E LLEA GNTEV A + + H+ KL+Q + ++ E+EF KL + ++ R F+ A+ N KNR+ NI+P+E +RV L IRG+EGSDYINAS+IDGYR ++AYIA Q P+ T EDFWRMLW+ + +V++L + E +K H YWP +S RYQ+FVVDP+ EYNMP YILREFKVTDARDG+ R +RQFQFT WP G PK E +DFI QVHKTKEQFG P+ +HC+ G GRTGVFI LSIVL+R++ E VVDM+QT+K L QR +VQTE+QY+ CY A L+YL +++
Sbjct: 1195 SDPVEMRRLNYQTQGMREHPPVSVCALADHIERLRANDSLRFSQEYESVDPG--QQFTWENSNLEVNKPKNRYANVIAYDHSRVVLTPVDGVPGSDYINGNYIDGYRKQNAYIATQGPLPETLSDFWRMVWEQRTSTIVMMTRLEEKSRVKCDQYWPSRGTETYGMIQVSMLDTVELATYSVRTFALYKNGSSEKREVRQFQFMAWPDHGVPEYPTPILAFLRRVKACNPPDAGPMVVHCSAGVGRTGCFIVIDAMLERMKHEKSVDIYGHVTCMRSQRNYMVQTEDQYIFIHEALLEAATCGNTEVPARSLYTHIQKLTQ--APPGDTVTAMELEFKKLANSKAHTSR-------FISAS--LPCNKFKNRLVNIMPFESSRVCLQPIRGVEGSDYINASFIDGYRQQKAYIATQGPLSETTEDFWRMLWEHNSTIVVMLTKLREMGREKCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDARDGQSRTIRQFQFTDWPEQGVPKTGEGFIDFIGQVHKTKEQFGQDGPITVHCSAGVGRTGVFITLSIVLERMRYEGVVDMFQTIKTLRTQRPAMVQTEDQYQLCYRAALEYLGSFD 1787 HSP 2 Score: 202.601 bits (514), Expect = 1.373e-51 Identity = 103/263 (39.16%), Postives = 150/263 (57.03%), Query Frame = 1
Query: 5092 NQAVNMTKNRVRNIIPYEWNRVVLNAIRGIEGSDYINASYIDGYRDRRAYIAAQSPIPSTVEDFWRMLWDQHCGVVIVLNQPHEDKSHI----YWPINKSIRYQFFVVDPVVEYNMPNYILREFKVTDARDGEFRALRQFQFTQWPNHGCPKESESILDFIRQVHKTKEQFGHMEPMVIHCNTGSGRTGVFIALSIVLDRLQQESVVDMYQTVKLLHKQRIGLVQTEEQYEFCYMAVLDYLSNYEKILEKSHLY*TYQDLSES 5868
N VN KNR N+I Y+ +RVVL + G+ GSDYIN +YIDGYR + AYIA Q P+P T+ DFWRM+W+Q ++++ + E+KS + YWP + Y V + + Y +R F + E R +RQFQF WP+HG P+ IL F+R+V PMV+HC+ G GRTG FI + +L+R++ E VD+Y V + QR +VQTE+QY F + A+L+ + + LY Q L+++
Sbjct: 1255 NLEVNKPKNRYANVIAYDHSRVVLTPVDGVPGSDYINGNYIDGYRKQNAYIATQGPLPETLSDFWRMVWEQRTSTIVMMTR-LEEKSRVKCDQYWPSRGTETYGMIQVSMLDTVELATYSVRTFALYKNGSSEKREVRQFQFMAWPDHGVPEYPTPILAFLRRVKACNPP--DAGPMVVHCSAGVGRTGCFIVIDAMLERMKHEKSVDIYGHVTCMRSQRNYMVQTEDQYIFIHEALLEAATCGNTEVPARSLYTHIQKLTQA 1514 HSP 3 Score: 157.918 bits (398), Expect = 7.008e-38 Identity = 250/1151 (21.72%), Postives = 447/1151 (38.84%), Query Frame = 1
Query: 277 NSQITFTENDEAP----KISLIIQSPNVLLFKSMILACSSTGHPVPSISWKINESPIEELKSPLKKLQNPPRIFSIKNYQNSVLVITQLIESDSNSVLICEAENNAGFD-SRQQQLKVISTETDIPSGFPVFQNNFFPIIKPYNSNVTLVCQAYGNPPPLIQWFKNYELINESFTKIKILNDGNLLLVQVTREDKGIYHCQAQNTNGLRLSDPSTLDITSYPISPNSLIIERFASDNVEISWRSGLNDVTEQENFILHYREVPENITEKQIMSKFVYLTISEKKSIY--KYNLKDLFPFTTYCIWMESENPLGVSPPTIALTVKTLPTSPQLSPRSITATSISNTAILVAWRPPERKFGKFKYYQIIYTNNDGFLPQHWRQFAVKDDNV-MLTHLIASELYHIRVKIVNEIGHGPLSKTISIKTIAGTLSQCPDFKITEIFQSHIKLQWGTPDPVKLFKLIQYNLLCWDVRLKIVNATAKSSTLF-PILNHNLSMNEMEYVLYLKNEKEIKCRLSAINSDGKGM---PTEIQASTVNKGVNYQNLIHIDKIGSTYITFQWRPPSKFSFDYFLWIYQIFDSEKLDRA----------VKLPKIKINISDSASAENGW--FVYNYTNAFSSSRYILGLRYLCRDSTDILREYVHRSDLVSTMKSVPSDSPKDLVVKEIDSNSALVSWKPLDQVHSNGIITHYEVRYYAPKKEESTERFINVSETSAILSNL-KYFHYVIYVRAFTKVGGG-----SWSNPKNY---YRQNLEEFPIPTTIKGERKSETEINISWELPVLSEKNLAHAAIEGFIILYAPVESSPKWIKYTVQSKNLSAVIKGLEPDLRYQFQIAATNYAGFNGNFSEIVQ------EMPKNFPNLNLKTVPDLRCSVQSSNRLKVEWSSPSISTDLLKFEIRYSGNLSYITEIGLKKSEFIDMESKSVNFETLVNRYDVTLENLQSNALYKIAVRAIYQNKELYESHRETTCDTMPAVPNLVKPPIIVGLD-EEKSKVIIKLHRCSQRNGKISYYFVIVAAFQGNKNQQISFQEDTESYTFMELSVNTRSNNAKGEYIAIMKDINDIFK--VSGKDHS---SVLLGDGTHDENHLSVNKKLEKNFNYRCFARVCLKYSNNSLCKSSPWSEPFRI 3594
++++T E D+ P I + Q V ++ + C+++G+P P ISW + P++ S + IK ++ L I ESD C A N+AG S L V P + P +V L C A G P P ++W K + TK + + G +L G Y C A ++ G+ + + + + + P P SLI+ + +V ++W SG + +++ YR SK E + +Y++ L P++ Y + + N +G PP+ + +T +P P + A +S T +LV W PPE G+ + Y++ YT++ F W++ +D ++ ++ L+ Y +RV +G GP S + +KT G +Q F+ + I L W P ++ K Y L W+ ++ K +F P ++ + LK + K L+A + G G+ P E + + G + + +D I ST + W+PP + + YQ+ S +L+ V LP+ + + E + V YT +R ++ +V+T +VP +++ N+AL+ W+P ++ G + Y +RY +++ T R ++ ++ L K Y+ + A + G G S P++ Y QNL+ + TT ++W+ P L E+N I ++++Y + S T ++ I+GL+PD Y ++ A G G S +Q MP+ N +K V ++ SV + W P + F+I Y+ +SV + + R +T LQ + Y + + + ++ + T P + P LD EE K+ I L + + +++++V + + ED + M NN + D + ++ K S +LGD N+ NK L YR F LK +S SP+SEP +
Sbjct: 119 SAKLTVLEEDQIPHGFPTIDMGPQLKVVERTRTATMLCAASGNPDPEISWFKDFLPVDINSSNGR----------IKQLRSGALQIENSEESDQGK-YECVAVNSAGTRYSAPANLYVRVRRVPPRFSIPPTNHEVMP-----GGSVNLTCVAVGAPMPYVKWMKG----EQELTKEEEMPIGRNVLELTNIRQSGNYTCVAISSLGM-IDTTAQITVKALPRPPASLIVTETTATSVTLTWDSGNPEPVSY--YVIQYR------------SKISDNGFQEVDGVASTRYSIGGLSPYSEYEFRVMAVNNIGRGPPSGMVETRTSEQAPSSPPLRVQARMLSATTMLVQWEPPEEPNGQIRGYRVYYTSDLHFPLSTWQKHNTEDSSLTTISGLVPDITYGLRVLAFTSVGDGPPSDILQVKTQQGVPAQPTGFEAEAELDTRIMLSWLWPVQDQITK---YELTYWE-----ADSDNKHHVIFDPAGSYAIDS--------LKPDTLYKFSLAARSEMGLGVYTQPIEARTAQSVPGAPPRR-VEVDNINSTALRVSWKPPLQQKQHGHIRGYQVVYS-RLENGEPRGQPIILDVALPEAQEAVISGLLPETTYSVTVAAYTTKGDGAR--------------------SKAKVVTTTGAVPGKP--TMIISTTIGNTALIQWQPPKEM--VGELMGYRLRYKREEEDIYTVRDFRRTDDHFTVTGLHKGATYIFKLCAKNRAGNGEEYSKEISTPEDVPSSYPQNLKVVGLTTTT---------TKLAWDPPPLPERN---GKIVRYVVVYRDINSHQNQTNGTADTE---MTIQGLKPDTTYDIRVRAFTGKG-GGPISPSIQSRTMSTSMPEFTKNFGVKAV--MKTSVL------LTWEVPETYKSQVPFKILYN--------------------QQSVEVQGDLKRKLIT--RLQPDTDYSFVL--MSRGNSAGGLQQQVSIRTAPDL--FTTKPAHQKLDPEEGGKLAITLPEV-HNSALVRWFYIVVVPVTPSTLRHWENPEDIDLDELM-------GNNRDAAVRRRRRQTQDFLRPYIAAKLESLPERFVLGDEKTYSNYY--NKPLPGQQQYRTFILAALK-DRDSTFTVSPFSEPMMV 1131 HSP 4 Score: 121.324 bits (303), Expect = 9.433e-27 Identity = 205/879 (23.32%), Postives = 325/879 (36.97%), Query Frame = 1
Query: 370 LACSSTGHPVPSISWKINESPIEELKSPLKKLQNPPRIFSIKNYQNSVLVITQLIESDSNSVLICEAENNAGFDSRQQQLKVISTETDIPSGFPVFQNNFFPIIKPYNSNVTLVCQAYGNPPPLIQWFKNYEL--INESFTKIKILNDGNLLLVQVTREDKGIYHCQAQNTNGLRLSDPSTLDI------TSYPISPNSLIIERFASDNVE----------ISWRSGLNDVTEQENFILHYREVPENITEKQIMSKFVYLTISEKKSIYKYNLKDLFPFTTYCIWMESENPLGVSPPTIALTVKTLPTSPQLSPRSITATSISNTAILVAWRP--PERKFGKFKYYQIIY---TNNDGFLPQHWRQFAVKDDNVMLTHLIASELYHIRVKIVNEIGHGPLSKTISIKTIAGTLSQCP-DFKITEIFQSHIKLQWGTPDPVKLFKLIQYNLLCWDVRLKIVNATAKSSTLFPI---LNHNLSMNEMEYVLYLKNEKEIKCRLSAINSDGKGMPTEIQASTVNKGVNYQNL-IHIDKIGSTYITFQWRPPSKFSFDYFLWIYQIFDSEKLDRAVKLPKIKINISDSASAENGWFVYNYTNAFSSSRYILGLRYLCRDSTDILREYVHRSDLVSTMKSVPSDSPKDLVVKEIDSNSALVSWKPLDQVHSNGIITHYEVRYYAPKKEESTERFINV------SETSAILSNLKYFHYVIYVRAFTKVGGGSWSNPKNYYRQNLEEFPIPTTIKGERKSETEINISWELPVLSEKNLAHAAIEGFIILYAPVESSPKWIKYTVQSKNLSA---VIKGLEPDLRYQFQIAATNYAGFNGNFSEIV---QEMPKNFPNLNLKTVPDLRCSVQSSNRLKVEWSSPSI 2886
C + G P P I+W +K K + + SVL I L ++ C A N+ G + +L V+ E IP GFP + T++C A GNP P I WFK++ IN S +IK L G L + D+G Y C A N+ G R S P+ L + + I P + + S N+ + W G ++T++E E I + LT N++ +T C+ + S LG+ T +TVK LP P S+ T + T++ + W PE YY I Y +++GF V + L Y RV VN IG GP S + +T S P + + + + +QW P+ + +++ S FP+ HN + + + L + R+ A S G G P++I +GV Q + T I W P + + Y DS+ + P I DS + +Y ++ A +R +GL + T +SVP P+ + V I+S + VSWKP Q +G I Y+V Y + E + I + ++ + I L Y + V A+T G G+ S K PT I T + I W+ P K + + G+ + Y E YTV+ + + GL Y F++ A N AG +S+ + +++P ++P NLK V ++ K+ W P +
Sbjct: 52 FVCQAVGEPKPRITW---------MKKGKKVSSQRFEVIEFDDGSGSVLRIQPLRTHRDEAIYECTATNSVGEINTSAKLTVLE-EDQIPHGFPTIDMGPQLKVVERTRTATMLCAASGNPDPEISWFKDFLPVDINSSNGRIKQLRSGALQIENSEESDQGKYECVAVNSAGTRYSAPANLYVRVRRVPPRFSIPPTNHEVMPGGSVNLTCVAVGAPMPYVKWMKGEQELTKEE--------------EMPIGRNVLELT----------NIRQSGNYT--CVAISS---LGMIDTTAQITVKALPRPPA----SLIVTETTATSVTLTWDSGNPE----PVSYYVIQYRSKISDNGFQEVD----GVASTRYSIGGLSPYSEYEFRVMAVNNIGRGPPSGMVETRTSEQAPSSPPLRVQARMLSATTMLVQWEPPEEP-------------NGQIRGYRVYYTSDLHFPLSTWQKHNTEDSSLTTISGLVPDITYGLRVLAFTSVGDGPPSDILQVKTQQGVPAQPTGFEAEAELDTRIMLSWLWPVQDQITKYELTYWEADSDNKHHVIFDPAGSYAI-DSLKPDT---LYKFSLA---ARSEMGLGVYTQPIE------------ARTAQSVPGAPPRRVEVDNINSTALRVSWKPPLQQKQHGHIRGYQVVYSRLENGEPRGQPIILDVALPEAQEAVISGLLPETTYSVTVAAYTTKGDGARSKAKVVTTTGAVPGK-PTMIISTTIGNTAL-IQWQPP----KEMV-GELMGYRLRYKREEED----IYTVRDFRRTDDHFTVTGLHKGATYIFKLCAKNRAGNGEEYSKEISTPEDVPSSYPQ-NLKVV------GLTTTTTKLAWDPPPL 829
BLAST of Protein tyrosine phosphatase receptor type D vs. Ensembl Xenopus
Match: brdt (bromodomain, testis-specific [Source:Xenbase;Acc:XB-GENE-983868]) HSP 1 Score: 721.85 bits (1862), Expect = 0.000e+0 Identity = 338/626 (53.99%), Postives = 450/626 (71.88%), Query Frame = 1
Query: 3949 NADSVQMCQ-DGTKLSPVLVSDSIKLRIGSQKSENISDRPSISICNLYQYVTDLKANDCTLLQAEFETLNTNLDDRFTWQRSNIDSNKSKNRYANVVAYDHTSVLLTPVDDVIGSDYINANYIDGYQRQNAYIATQGPLPDTTDDFWRMVWEQRSNCIVMMTRLEERSGIKCHQYWPNRGFICYGQMIVSHIDTFVLAYYTIRLFEIRHSKYSEKREIQHFQFTAWPDHGVPKLSTPLLMFIRRVRSIGKIESCPKIVHCSAGVGRTGAFIVVDAQLERIKQEKNIDVFNYVSKIRCQRNYMVQTQAQYQFILETLLEAVEDGNTEVMACNFHAHVTKLSQIGISGSNQLSGFEMEFSKLNSLASNRGRHGVMLADFVKAAGNQAVNMTKNRVRNIIPYEWNRVVLNAIRGIEGSDYINASYIDGYRDRRAYIAAQSPIPSTVEDFWRMLWDQHCGVVIVLNQPHE---DKSHIYWPINKSIRYQFFVVDPVVEYNMPNYILREFKVTDARDGEFRALRQFQFTQWPNHGCPKESESILDFIRQVHKTKEQFGHMEPMVIHCNTGSGRTGVFIALSIVLDRLQQESVVDMYQTVKLLHKQRIGLVQTEEQYEFCYMAVLDYLSNYE 5814
N+D C + +++P +D +++R + ++ + + P I I +L ++ LKAND L E+E+++ +FTW+ SN++ NK+KNRYANV+AYDH+ V+L PV+ +IGSDYINANYIDGY++QNAYIATQG LP+T DFWRMVWEQRS +VMMT+LEE+S IKC QYWP+RG YG + V+ +DT LA + +R F + S SEKRE++ FQFTAWPDHGVP+ TP L F+RRV++ ++ P +VHCSAGVGRTG FIV+DA LERIK EK +D++ +V+ +R QRNYMVQT+ QY FI + LLEAV GNTEV A N + ++ KL+QI + ++G E+EF +L + ++ R F+ A N N KNR+ NI+PYE RV L IRG+EGSDYINAS+IDGYR ++AYIA Q P+ T EDFWRMLW+ + +V++L + E +K H YWP +S RYQ+FVVDP+ EYNMP YILREFKVTDARDG+ R +RQFQFT WP G PK E +DFI QVHKTKEQFG P+ +HC+ G GRTGVFI LSIVL+R++ E VVD++QTVK+L QR +VQTE++Y+FCY A L+YL +++
Sbjct: 1282 NSDPRTKCLLNNAEIAPHHPTDPVEMRRINFQTPGMLNHPPIPIADLSEHTEHLKANDNLKLSQEYESVDPG--QQFTWEHSNLEVNKAKNRYANVIAYDHSRVILLPVEGIIGSDYINANYIDGYRKQNAYIATQGALPETFGDFWRMVWEQRSATVVMMTKLEEKSRIKCDQYWPSRGTETYGMIQVTLLDTIELATFCVRTFSLHKSGSSEKREVRQFQFTAWPDHGVPEYPTPFLAFLRRVKTCNPPDAGPVVVHCSAGVGRTGCFIVIDAMLERIKHEKTVDIYGHVTLMRSQRNYMVQTEDQYSFIHDALLEAVACGNTEVPARNLYTYIQKLAQIEL--GEHVTGMELEFKRLANSKAHTSR-------FISA--NLPCNKFKNRLVNIMPYESTRVCLQPIRGVEGSDYINASFIDGYRQQKAYIATQGPLAETTEDFWRMLWENNSTIVVMLTKLREMGREKCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDARDGQSRTVRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKEQFGQDGPISVHCSAGVGRTGVFITLSIVLERMRYEGVVDIFQTVKMLRTQRPAMVQTEDEYQFCYQAALEYLGSFD 1894 HSP 2 Score: 202.216 bits (513), Expect = 2.768e-51 Identity = 104/262 (39.69%), Postives = 152/262 (58.02%), Query Frame = 1
Query: 5092 NQAVNMTKNRVRNIIPYEWNRVVLNAIRGIEGSDYINASYIDGYRDRRAYIAAQSPIPSTVEDFWRMLWDQHCGVVIVLNQPHEDKSHI----YWPINKSIRYQFFVVDPVVEYNMPNYILREFKVTDARDGEFRALRQFQFTQWPNHGCPKESESILDFIRQVHKTKEQFGHMEPMVIHCNTGSGRTGVFIALSIVLDRLQQESVVDMYQTVKLLHKQRIGLVQTEEQYEFCYMAVLDYLSNYEKILEKSHLY*TYQDLSE 5865
N VN KNR N+I Y+ +RV+L + GI GSDYINA+YIDGYR + AYIA Q +P T DFWRM+W+Q V+++ + E+KS I YWP + Y V + + + +R F + + E R +RQFQFT WP+HG P+ L F+R+V P+V+HC+ G GRTG FI + +L+R++ E VD+Y V L+ QR +VQTE+QY F + A+L+ ++ + +LY Q L++
Sbjct: 1362 NLEVNKAKNRYANVIAYDHSRVILLPVEGIIGSDYINANYIDGYRKQNAYIATQGALPETFGDFWRMVWEQRSATVVMMTK-LEEKSRIKCDQYWPSRGTETYGMIQVTLLDTIELATFCVRTFSLHKSGSSEKREVRQFQFTAWPDHGVPEYPTPFLAFLRRVKTCNPP--DAGPVVVHCSAGVGRTGCFIVIDAMLERIKHEKTVDIYGHVTLMRSQRNYMVQTEDQYSFIHDALLEAVACGNTEVPARNLYTYIQKLAQ 1620 HSP 3 Score: 153.68 bits (387), Expect = 1.692e-36 Identity = 253/1086 (23.30%), Postives = 412/1086 (37.94%), Query Frame = 1
Query: 370 LACSSTGHPVPSISW-----KINESPIEELKSPLKKLQNPPRIFSIKNYQNSVLVITQLIESDSNSVLICEAENNAGFDSRQQQLKVISTETDIPSGFPVFQNNFFPIIKPYNSNVTLVCQAYGNPPPLIQWFKNYELINESFT--KIKILNDGN----LLLVQVTRE-DKGIYHCQAQNTNGLRLSDPSTLDITSYPISPNSLII----ERFASDNVEIS------------WRSGLNDVTEQENFILHYREVPENITEKQIMSKFVYLTISEKKSIYKYNLKDLFPFTTYCIWMESENPLGVSPPTIALTVKTLPTSPQLSPRSITATSISNTAILVAWRPPERKFGKFKYYQIIYTNNDGFLPQHWRQFAVKDDNVMLTHLIAS----ELYHIRVKIVNEIGHGPLSKTISIKTIAGTLSQCP-DFKITEIFQSHIKLQWGTPDPVKLFKLIQYNLLCWDVRLKIVNATAKSSTLFPILNHNLSMNEMEYVLYLKNEKEIKCRLSAINSDGKG-MPTEIQASTVNKGVNYQNL-IHIDKIGSTYITFQWRPPSKFSFDYFLWIYQIFDSEKLDRAVKLPKIKINISDSASAENGWFVYNYTNAFSSSRYILGLRYLCRDSTDILREYVHRSDLVSTMKSVPSDSPKDLVVKEIDSNSALVSWKPLDQVHSNGIITHYEVRYYAPKKEESTERFIN--VSETSAILSNL--KYFHYVIYVRAFTKVGGGSWSNPKNYYRQNLEEFPIPTTIKGERKSETEINISWELPVLSEKNLAHAAIEGFIILYAPVE----SSPKWIKYTVQSKNLSAVIKGLEPDLRYQFQIAATNYAGFNGNFSEIVQEMPKNFPNLNLKTVPDLRCSVQSSNRLKVEWSSPSISTDLLKFEIRYSGNLSYITEIGLKKSEFIDMESKSVNFETLVNRYDVTLENLQSNALYKIAVRAIYQNKELYESHRETTCDTMPAVPNLVKPPIIVGLDEEKSKVIIKLHRCSQRNGKIS-YYFVIVAAFQGNKNQQISFQEDTESYTFMELSVNT------RSNNAKG--------EYIAIMKD--INDIFKVSGKDHSSVLL 3447
C +TG P P ++W K+N E ++ +VL I L +V C A+N G + +L V+ E +PSGFP + T++C A GNP P I WFK++ ++ + + +IK L G L ++ + E D+G Y C A N+ G+R S P+ L + ++P I+ E NV I+ W G D+T +++ V N+ E LT N+K+ +T C+ M S LGV +TVK+LP +P + T + T+I V W YY I Y + P + +K+D + I Y I V VN IG GP S+ + +T + P + + + + + +QW P ++ N R+ + + + L +N+ + + + L + R+ A S G G + IQ T +GV Q + + T I W PP + S + Y+ + ++ D A++ Y ++ Y+ R R S + + + TM+S PS P+++ S + LVSW P NG++ Y VRY A +++ + + +T+ IL K+ Y I V A T+VG G S P P ++ E + T I + W PV +N H I G+ + Y +E S IK + + VI GL+P+ Y +AA G + P PDL S L VEW P S + L Y + G + + ++ F L +Y T + + ++K+AV+ E DT P L++ I+ + + + + L ++RNG I+ Y A K Q+I S+ +L+ NT R++ KG +Y + D + FKV +SVLL
Sbjct: 43 FVCQATGDPKPRVTWNKRGKKVNSQRFETIE--------------FDEGAGAVLRIQPLRTPRDENVYECVAQNVHGEEVVSAKLTVLR-EDQLPSGFPNIDMGPQLKVVERTRTATMLCAASGNPDPEITWFKDFLPVDPASSNGRIKQLRSGKTTNCALQIENSEETDQGKYECVATNSAGVRYSSPANLYVRVRRVAPRFSILPVSHEIMPGGNVNITCVAVGSPMPYVKWMVGAEDLTPEDDM-----PVGRNVLE---------LT----------NVKESANYT--CVAMSS---LGVIESVAQITVKSLPKAPG----TPVVTETTATSITVTWD--SGNPDPVSYYVIEYKSKSQDGP-----YQIKEDITTTRYSIGGLSPNSEYEIWVSAVNSIGQGPPSEPVVTRTGEQAPASAPRNVQARMLSSTTMIIQWEEP--------VEPNGQIRGYRVYYTMEPDQPVSSW--LKYNVDDSLLTTIGSLLEHETYTVRVLAFTSVGDGPLSDPIQVKT-QQGVPGQPMNFRAEAKSETSIGLTWSPPRQDSIVKYELNYREGEGGN----------EVRTFDPATS------YTVEGLKPNTEYL--FRLAARSSHGLGAWTLDIKE--RTMQSKPSAPPRNVKCVSSKSTTILVSWLPPPAESQNGVLAGYSVRYSALDSDDTRPKEVKDIPPQTTQILLEALEKWTVYRITVVAHTEVGPGPESPPVEIRTDEDVPSAPPRKVEVEVLNSTAIKVFWRSPV---QNRQHGQIRGYQVHYVRMENGEASGLTLIKDVMLADAQEMVISGLQPETSYSVTVAAYTMKGDGARSKPKLVTTRGAVPGK-----PDLFVHQNSDGSLLVEWEPPRESEGHI---------LGYRLQFGRQDVMLLS----TLEFGELEKKYLATNIHKGATYVFKMAVKGRVGLSEEAVKEFIVPEDTPKGFPQLIEKGIVTSMSIQLNWLPPVL---AERNGVITKYTLAYRVAGSSEKLQEIDLPSSDNSFILTDLNPNTVYEVKIRAHTRKGPGPYSPTVQYRTFLLDQVLPKNFKVKMVTKTSVLL 1018 HSP 4 Score: 148.288 bits (373), Expect = 7.801e-35 Identity = 209/965 (21.66%), Postives = 390/965 (40.41%), Query Frame = 1
Query: 271 LINSQITFTENDEAPK----ISLIIQSPNVLLFKSMILACSSTGHPVPSISWKINESPIEELKS--PLKKLQNPPRIFSIKNYQNSVLVITQLIESDSNSVLICEAENNAGFDSRQQQLKVISTETDIP--SGFPVFQNNFFPIIKPYNSNVTLVCQAYGNPPPLIQWFKNYELINESFTKIKILNDGNLLLVQVTREDKGIYHCQAQNTNGLRLSDPSTLDITSYPISPNSLIIERFASDNVEISWRSGLNDVTEQENFILHYREVPENITEKQIMSKFVYLTISEKKSIYKYNLKDLFPFTTYCIWMESENPLGVSPPTIALTVKTLPTSPQLSPRSITATSISNTAILVAWRPPERKFGKFKYYQIIYTNNDGFLPQHWRQFAVKDDNVMLT--HLIASELYHIRVKIVNEIGHGPLSKTISIKTIAGTLSQCPDFKITEIFQSHIKLQWGTPDPVKLFKLIQYNLLCWDVRLKIVNATAKSSTLFPILNHNLSMNEMEYVLYLKNEKEIKCRLSAINSDGKGMPT-EIQASTV-NKGVNYQNLIHIDKIGSTYITFQWRPPSKFSFDYFLWIYQIFDSEKLDRAVKLPKIKINISDSAS-----AENGWFVYNYTNAFSSSRYILGLRYLCRDSTDILREYVHRSDLVSTMKSVPSDSPKDLVVKEIDSNSALVSWKPLDQVHSNGIITHYEVRYYAPKKEEST-----ERFINVSETSAILSNLK-YFHYVIYVRAFTKVGGGSWSNPKNYYRQNLEEFPIPTTIKGERKSETEINISWELPVLSEKNLAHAAIE---GFIILYAPVESSPKWIKYTVQSKNLSAVIKGLEPDLRYQFQIAATNYAGFNGNFSE---IVQEMPKNFPNLNLKTVPDLRCSVQSSNRLKVEWSSPSISTDLLKFEIRYSGNLSYITEIGLKKSEFIDMESKSVNFETLVNRYDVTLENLQSNALYKIAVRA 3078
++++++T D+ P I + Q V ++ + C+++G+P P I+W + P++ S +K+L++ N L I E+D C A N+AG + P S PV I P NV + C A G+P P ++W + E T + G +L ++ Y C A ++ G+ + + + + S P +P + ++ + ++ ++W SG D +++ Y+ S+ I E + +Y++ L P + Y IW+ + N +G PP+ + +T +P +PR++ A +S+T +++ W P G+ + Y++ YT W ++ V DD+++ T L+ E Y +RV +G GPLS I +KT G Q +F+ ++ I L W P Q +++ +++ + + T P ++ V LK E RL+A +S G G T +I+ T+ +K + ST I W PP S + L Y + S LD PK +I + A W VY R T++ + T + VPS P+ + V+ ++S + V W+ Q +G I Y+V Y + E++ + + ++S L+ Y + V A+T G G+ S PK + P + + S+ + + WE P SE ++ ++ ++L + +E KY + + A Y F++A G + + + ++ PK FP L + + +S +++ W P ++ + + L+Y +K + ID+ S +F L +L N +Y++ +RA
Sbjct: 108 VVSAKLTVLREDQLPSGFPNIDMGPQLKVVERTRTATMLCAASGNPDPEITWFKDFLPVDPASSNGRIKQLRS-------GKTTNCALQIENSEETDQGKYE-CVATNSAGVRYSSPANLYVRVRRVAPRFSILPVSHE-----IMP-GGNVNITCVAVGSPMPYVKWM----VGAEDLTPEDDMPVGRNVLELTNVKESANYTCVAMSSLGV-IESVAQITVKSLPKAPGTPVVTETTATSITVTWDSGNPDPVSY--YVIEYKS----------KSQDGPYQIKEDITTTRYSIGGLSPNSEYEIWVSAVNSIGQGPPSEPVVTRTGEQAPASAPRNVQARMLSSTTMIIQWEEPVEPNGQIRGYRVYYTMEPDQPVSSWLKYNV-DDSLLTTIGSLLEHETYTVRVLAFTSVGDGPLSDPIQVKTQQGVPGQPMNFRAEAKSETSIGLTWSPPR--------QDSIVKYELNYREGEGGNEVRTFDPATSYT--------VEGLKPNTEYLFRLAARSSHGLGAWTLDIKERTMQSKPSAPPRNVKCVSSKSTTILVSWLPPPAESQNGVLAGYSVRYS-ALDSDDTRPKEVKDIPPQTTQILLEALEKWTVY---------------RITVVAHTEVGPGPESPPVEIRTDEDVPSAPPRKVEVEVLNSTAIKVFWRSPVQNRQHGQIRGYQVHYVRMENGEASGLTLIKDVMLADAQEMVISGLQPETSYSVTVAAYTMKGDGARSKPKLVTTRG--AVPGKPDLFVHQNSDGSLLVEWEPPRESEGHILGYRLQFGRQDVMLLSTLEFGELEKKYLATNIHKGAT---------YVFKMAVKGRVGLSEEAVKEFIVPEDTPKGFPQL-------IEKGIVTSMSIQLNWLPPVLAE---RNGVITKYTLAYRVAGSSEKLQEIDLPSSDNSF---------ILTDLNPNTVYEVKIRA 978 HSP 5 Score: 96.2857 bits (238), Expect = 5.951e-19 Identity = 118/494 (23.89%), Postives = 210/494 (42.51%), Query Frame = 1
Query: 1126 YNLKDLFPFTTYCIWMESENPLGVSPPTIALTVKTLPTSPQLSPRSITATSISNTAILVAWRPP--ERKFGKFKYYQIIYT--NNDGFLPQHWRQFAVKDDNVMLTHLIASELYHIRVKIVNEIGHGPLSKTISIKTIAGTLSQCPDFKITEIFQS-HIKLQWGTPDPVKLFKLIQYNLLCWDVRLKIVNATAKSSTLFPILNHNLSMNEMEYVLYLKNEKEIKCRLSAINSDGKGMPTEIQASTVNKGVNYQNLIHIDKIGSTYITFQWRPPSKFSFDYFLWIYQIFDSEKLDRAVKLPKIKINISDSASAENGWFVYNY--TNAFSSSRYILGLRYLCRD--STDILREYVHRSDLVSTMKSVPSDSPK---DLVVKEI-DSNSALVSWKPLDQVHSNGIITHYEVRY-YAPKKEESTERFINVSETSAILSNLKYFH-YVIYVRAFTKVGGGSWSNPKNYYRQNLEEFPIPTTIKGERKSETEINISWELP 2562
Y ++ L P T Y + + + G+ T+ + +T+ + P PR++ S +T ILV+W PP E + G Y + Y+ ++D P+ + + ++L L +Y I V E+G GP S + I+T S P E+ S IK+ W +P + I+ + + +++ N A TL I + L+ + + L+ E ++A G G ++ + T V + + + + + +W PP +SE +L + ++ ++ E G Y TN + Y+ + R S + ++E++ VP D+PK L+ K I S S ++W P NG+IT Y + Y A E+ E + S+ S IL++L Y + +RA T+ G G +S P YR L + +P K + ++T + +SWE P
Sbjct: 561 YTVEGLKPNTEYLFRLAARSSHGLGAWTLDIKERTMQSKPSAPPRNVKCVSSKSTTILVSWLPPPAESQNGVLAGYSVRYSALDSDDTRPKEVKDIPPQTTQILLEALEKWTVYRITVVAHTEVGPGPESPPVEIRTDEDVPSAPPRKVEVEVLNSTAIKVFWRSPVQNRQHGQIRGYQVHY---VRMENGEASGLTL--IKDVMLADAQEMVISGLQPETSYSVTVAAYTMKGDGARSKPKLVTTRGAVPGKPDLFVHQNSDGSLLVEWEPPR--------------ESEGHILGYRLQFGRQDVMLLSTLEFGELEKKYLATNIHKGATYVFKMAVKGRVGLSEEAVKEFI-----------VPEDTPKGFPQLIEKGIVTSMSIQLNWLPPVLAERNGVITKYTLAYRVAGSSEKLQEIDLPSSDNSFILTDLNPNTVYEVKIRAHTRKGPGPYS-PTVQYRTFLLDQVLPKNFKVKMVTKTSVLLSWEFP 1023
BLAST of Protein tyrosine phosphatase receptor type D vs. Ensembl Xenopus
Match: brdt (bromodomain, testis-specific [Source:Xenbase;Acc:XB-GENE-983868]) HSP 1 Score: 721.85 bits (1862), Expect = 0.000e+0 Identity = 338/626 (53.99%), Postives = 450/626 (71.88%), Query Frame = 1
Query: 3949 NADSVQMCQ-DGTKLSPVLVSDSIKLRIGSQKSENISDRPSISICNLYQYVTDLKANDCTLLQAEFETLNTNLDDRFTWQRSNIDSNKSKNRYANVVAYDHTSVLLTPVDDVIGSDYINANYIDGYQRQNAYIATQGPLPDTTDDFWRMVWEQRSNCIVMMTRLEERSGIKCHQYWPNRGFICYGQMIVSHIDTFVLAYYTIRLFEIRHSKYSEKREIQHFQFTAWPDHGVPKLSTPLLMFIRRVRSIGKIESCPKIVHCSAGVGRTGAFIVVDAQLERIKQEKNIDVFNYVSKIRCQRNYMVQTQAQYQFILETLLEAVEDGNTEVMACNFHAHVTKLSQIGISGSNQLSGFEMEFSKLNSLASNRGRHGVMLADFVKAAGNQAVNMTKNRVRNIIPYEWNRVVLNAIRGIEGSDYINASYIDGYRDRRAYIAAQSPIPSTVEDFWRMLWDQHCGVVIVLNQPHE---DKSHIYWPINKSIRYQFFVVDPVVEYNMPNYILREFKVTDARDGEFRALRQFQFTQWPNHGCPKESESILDFIRQVHKTKEQFGHMEPMVIHCNTGSGRTGVFIALSIVLDRLQQESVVDMYQTVKLLHKQRIGLVQTEEQYEFCYMAVLDYLSNYE 5814
N+D C + +++P +D +++R + ++ + + P I I +L ++ LKAND L E+E+++ +FTW+ SN++ NK+KNRYANV+AYDH+ V+L PV+ +IGSDYINANYIDGY++QNAYIATQG LP+T DFWRMVWEQRS +VMMT+LEE+S IKC QYWP+RG YG + V+ +DT LA + +R F + S SEKRE++ FQFTAWPDHGVP+ TP L F+RRV++ ++ P +VHCSAGVGRTG FIV+DA LERIK EK +D++ +V+ +R QRNYMVQT+ QY FI + LLEAV GNTEV A N + ++ KL+QI + ++G E+EF +L + ++ R F+ A N N KNR+ NI+PYE RV L IRG+EGSDYINAS+IDGYR ++AYIA Q P+ T EDFWRMLW+ + +V++L + E +K H YWP +S RYQ+FVVDP+ EYNMP YILREFKVTDARDG+ R +RQFQFT WP G PK E +DFI QVHKTKEQFG P+ +HC+ G GRTGVFI LSIVL+R++ E VVD++QTVK+L QR +VQTE++Y+FCY A L+YL +++
Sbjct: 1295 NSDPRTKCLLNNAEIAPHHPTDPVEMRRINFQTPGMLNHPPIPIADLSEHTEHLKANDNLKLSQEYESVDPG--QQFTWEHSNLEVNKAKNRYANVIAYDHSRVILLPVEGIIGSDYINANYIDGYRKQNAYIATQGALPETFGDFWRMVWEQRSATVVMMTKLEEKSRIKCDQYWPSRGTETYGMIQVTLLDTIELATFCVRTFSLHKSGSSEKREVRQFQFTAWPDHGVPEYPTPFLAFLRRVKTCNPPDAGPVVVHCSAGVGRTGCFIVIDAMLERIKHEKTVDIYGHVTLMRSQRNYMVQTEDQYSFIHDALLEAVACGNTEVPARNLYTYIQKLAQIEL--GEHVTGMELEFKRLANSKAHTSR-------FISA--NLPCNKFKNRLVNIMPYESTRVCLQPIRGVEGSDYINASFIDGYRQQKAYIATQGPLAETTEDFWRMLWENNSTIVVMLTKLREMGREKCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDARDGQSRTVRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKEQFGQDGPISVHCSAGVGRTGVFITLSIVLERMRYEGVVDIFQTVKMLRTQRPAMVQTEDEYQFCYQAALEYLGSFD 1907 HSP 2 Score: 202.216 bits (513), Expect = 3.057e-51 Identity = 104/262 (39.69%), Postives = 152/262 (58.02%), Query Frame = 1
Query: 5092 NQAVNMTKNRVRNIIPYEWNRVVLNAIRGIEGSDYINASYIDGYRDRRAYIAAQSPIPSTVEDFWRMLWDQHCGVVIVLNQPHEDKSHI----YWPINKSIRYQFFVVDPVVEYNMPNYILREFKVTDARDGEFRALRQFQFTQWPNHGCPKESESILDFIRQVHKTKEQFGHMEPMVIHCNTGSGRTGVFIALSIVLDRLQQESVVDMYQTVKLLHKQRIGLVQTEEQYEFCYMAVLDYLSNYEKILEKSHLY*TYQDLSE 5865
N VN KNR N+I Y+ +RV+L + GI GSDYINA+YIDGYR + AYIA Q +P T DFWRM+W+Q V+++ + E+KS I YWP + Y V + + + +R F + + E R +RQFQFT WP+HG P+ L F+R+V P+V+HC+ G GRTG FI + +L+R++ E VD+Y V L+ QR +VQTE+QY F + A+L+ ++ + +LY Q L++
Sbjct: 1375 NLEVNKAKNRYANVIAYDHSRVILLPVEGIIGSDYINANYIDGYRKQNAYIATQGALPETFGDFWRMVWEQRSATVVMMTK-LEEKSRIKCDQYWPSRGTETYGMIQVTLLDTIELATFCVRTFSLHKSGSSEKREVRQFQFTAWPDHGVPEYPTPFLAFLRRVKTCNPP--DAGPVVVHCSAGVGRTGCFIVIDAMLERIKHEKTVDIYGHVTLMRSQRNYMVQTEDQYSFIHDALLEAVACGNTEVPARNLYTYIQKLAQ 1633 HSP 3 Score: 145.591 bits (366), Expect = 6.237e-34 Identity = 223/1023 (21.80%), Postives = 387/1023 (37.83%), Query Frame = 1
Query: 370 LACSSTGHPVPSISW-----KINESPIEELKSPLKKLQNPPRIFSIKNYQNSVLVITQLIESDSNSVLICEAENNAGFDSRQQQLKVISTETDIPSGFPVFQNNFFPIIKPYNSNVTLVCQAYGNPPPLIQWFKNYELINESFT--KIKILNDGN----LLLVQVTRE-DKGIYHCQAQNTNGLRLSDPSTLDITSYPISPNSLII----ERFASDNVEIS------------WRSGLNDVTEQENF-----ILHYREVPEN---------------------------------ITEKQIMS-------------KFVYLTISEKKSIYKYNLKDLFPFTTYCI-----------WMESENPLGVSPPTIALTVKTLPTSPQLSPRSITATSISNTAILVAWRPPERKFGKFKYYQIIYTNNDGFLPQHWRQFAVKDDNVMLT--HLIASELYHIRVKIVNEIGHGPLSKTISIKTIAGTLSQCPDFKITEIFQSHIKLQWGTPDPVKLFKLIQYNLLCWDVRLKIVNATAKSSTLFPILNHNLSMNEMEYVLYLKNEKEIKCRLSAINSDGKGMPT-EIQASTV-NKGVNYQNLIHIDKIGSTYITFQWRPPSKFSFDYFLWIYQIFDSEKLDRAVKLPKIKINISDSAS-----AENGWFVYNYTNAFSSSRYILGLRYLCRDSTDILREYVHRSDLVSTMKSVPSDSPKDLVVKEIDSNSALVSWKPLDQVHSNGIITHYEVRYYAPKKEESTERFI--------------NVSETSAILSNLK-YFHYVIYVRAFTKVGGGSWSNPKNYYRQNLEEFPIPTTIKGERKSETEINISWELPVLSEKNLAHAAIE---GFIILYAPVESSPKWIKYTVQSKNLSAVIKGLEPDLRYQFQIAATNYAGFNGNFSE---IVQEMPKNFPNLNLKTVPDLRCSVQSSNRLKVEWSSPSISTDLLKFEIRYSGNLSYITEIGLKKSEFIDMESKSVNFETLVNRYDVTLENLQSNALYKIAVRA 3078
C +TG P P ++W K+N E ++ +VL I L +V C A+N G + +L V+ E +PSGFP + T++C A GNP P I WFK++ ++ + + +IK L G L ++ + E D+G Y C A N+ G+R S P+ L + ++P I+ E NV I+ W G D+T +++ +L V E+ +TE S + + K Y +K+ T Y I W+ + N +G PP+ + +T +P +PR++ A +S+T +++ W P G+ + Y++ YT W ++ V DD+++ T L+ E Y +RV +G GPLS I +KT G Q +F+ ++ I L W P + +++Y L + T P ++ V LK E RL+A +S G G T +I+ T+ +K + ST I W PP S + L Y + S LD PK +I + A W VY R T++ + T + VPS P+ + V+ ++S + V W+ Q +G I Y+V Y + E++ + + +E ++S L+ Y + V A+T G G+ S PK + P + + S+ + + WE P SE ++ ++ ++L + +E KY + + A Y F++A G + + + ++ PK FP L + + +S +++ W P ++ + + L+Y +K + ID+ S +F L +L N +Y++ +RA
Sbjct: 43 FVCQATGDPKPRVTWNKRGKKVNSQRFETIE--------------FDEGAGAVLRIQPLRTPRDENVYECVAQNVHGEEVVSAKLTVLR-EDQLPSGFPNIDMGPQLKVVERTRTATMLCAASGNPDPEITWFKDFLPVDPASSNGRIKQLRSGKTTNCALQIENSEETDQGKYECVATNSAGVRYSSPANLYVRVRRVAPRFSILPVSHEIMPGGNVNITCVAVGSPMPYVKWMVGAEDLTPEDDMPVGRNVLELTNVKESANYTCVAMSSLGVIESVAQITVKSLPKAPGTPVVTETTATSITVTWDSGNPDPVSYYVIEYKSKSQDGPYQIKEDITTTRYSIGGLSPNSEYEIWVSAVNSIGQGPPSEPVVTRTGEQAPASAPRNVQARMLSSTTMIIQWEEPVEPNGQIRGYRVYYTMEPDQPVSSWLKYNV-DDSLLTTIGSLLEHETYTVRVLAFTSVGDGPLSDPIQVKTQQGVPGQPMNFRAEAKSETSIGLTWSPP---RQDSIVKYELNYREGE----GGNEIRKTFDPATSYT--------VEGLKPNTEYLFRLAARSSHGLGAWTLDIKERTMQSKPSAPPRNVKCVSSKSTTILVSWLPPPAESQNGVLAGYSVRYS-ALDSDDTRPKEVKDIPPQTTQILLEALEKWTVY---------------RITVVAHTEVGPGPESPPVEIRTDEDVPSAPPRKVEVEVLNSTAIKVFWRSPVQNRQHGQIRGYQVHYVRMENGEASGLTLIKDVMLADAQWEMDDTAEYEMVISGLQPETSYSVTVAAYTMKGDGARSKPKLVTTRG--AVPGKPDLFVHQNSDGSLLVEWEPPRESEGHILGYRLQFGRQDVMLLSTLEFGELEKKYLATNIHKGAT---------YVFKMAVKGRVGLSEEAVKEFIVPEDTPKGFPQL-------IEKGIVTSMSIQLNWLPPVLAE---RNGVITKYTLAYRVAGSSEKLQEIDLPSSDNSF---------ILTDLNPNTVYEVKIRA 988 HSP 4 Score: 88.1965 bits (217), Expect = 1.558e-16 Identity = 121/509 (23.77%), Postives = 213/509 (41.85%), Query Frame = 1
Query: 1126 YNLKDLFPFTTYCIWMESENPLGVSPPTIALTVKTLPTSPQLSPRSITATSISNTAILVAWRPP--ERKFGKFKYYQIIYT--NNDGFLPQHWRQFAVKDDNVMLTHLIASELYHIRVKIVNEIGHGPLSKTISIKTIAGTLSQCPDFKITEIFQS-HIKLQWGTPDPVKLFKLIQYNLLCWDVRLKIVNATAKSSTLFP---ILNHNLSMN---EMEYVLY-LKNEKEIKCRLSAINSDGKGMPTEIQASTVNKGVNYQNLIHIDKIGSTYITFQWRPPSKFSFDYFLWIYQIFDSEKLDRAVKLPKIKINISDSASAENGWFVYNY--TNAFSSSRYILGLRYLCRD--STDILREYVHRSDLVSTMKSVPSDSPK---DLVVKEI-DSNSALVSWKPLDQVHSNGIITHYEVRY-YAPKKEESTERFINVSETSAILSNLK-YFHYVIYVRAFTKVGGGSWSNPKNYYRQNLEE--------FPIPTTIKGERKSETEINISWELP 2562
Y ++ L P T Y + + + G+ T+ + +T+ + P PR++ S +T ILV+W PP E + G Y + Y+ ++D P+ + + ++L L +Y I V E+G GP S + I+T S P E+ S IK+ W +P + I+ + + +++ N A TL + + M+ E E V+ L+ E ++A G G ++ + T V + + + + + +W PP +SE +L + ++ ++ E G Y TN + Y+ + R S + ++E++ VP D+PK L+ K I S S ++W P NG+IT Y + Y A E+ E + S+ S IL++L Y + +RA T+ G G +S P YR L + F + T K + ++T + +SWE P
Sbjct: 562 YTVEGLKPNTEYLFRLAARSSHGLGAWTLDIKERTMQSKPSAPPRNVKCVSSKSTTILVSWLPPPAESQNGVLAGYSVRYSALDSDDTRPKEVKDIPPQTTQILLEALEKWTVYRITVVAHTEVGPGPESPPVEIRTDEDVPSAPPRKVEVEVLNSTAIKVFWRSPVQNRQHGQIRGYQVHY---VRMENGEASGLTLIKDVMLADAQWEMDDTAEYEMVISGLQPETSYSVTVAAYTMKGDGARSKPKLVTTRGAVPGKPDLFVHQNSDGSLLVEWEPPR--------------ESEGHILGYRLQFGRQDVMLLSTLEFGELEKKYLATNIHKGATYVFKMAVKGRVGLSEEAVKEFI-----------VPEDTPKGFPQLIEKGIVTSMSIQLNWLPPVLAERNGVITKYTLAYRVAGSSEKLQEIDLPSSDNSFILTDLNPNTVYEVKIRAHTRKGPGPYS-PTVQYRTFLLDQGRAYQSFFFVFTNFKVKMVTKTSVLLSWEFP 1041
BLAST of Protein tyrosine phosphatase receptor type D vs. Ensembl Xenopus
Match: brdt (bromodomain, testis-specific [Source:Xenbase;Acc:XB-GENE-983868]) HSP 1 Score: 721.465 bits (1861), Expect = 0.000e+0 Identity = 338/626 (53.99%), Postives = 450/626 (71.88%), Query Frame = 1
Query: 3949 NADSVQMCQ-DGTKLSPVLVSDSIKLRIGSQKSENISDRPSISICNLYQYVTDLKANDCTLLQAEFETLNTNLDDRFTWQRSNIDSNKSKNRYANVVAYDHTSVLLTPVDDVIGSDYINANYIDGYQRQNAYIATQGPLPDTTDDFWRMVWEQRSNCIVMMTRLEERSGIKCHQYWPNRGFICYGQMIVSHIDTFVLAYYTIRLFEIRHSKYSEKREIQHFQFTAWPDHGVPKLSTPLLMFIRRVRSIGKIESCPKIVHCSAGVGRTGAFIVVDAQLERIKQEKNIDVFNYVSKIRCQRNYMVQTQAQYQFILETLLEAVEDGNTEVMACNFHAHVTKLSQIGISGSNQLSGFEMEFSKLNSLASNRGRHGVMLADFVKAAGNQAVNMTKNRVRNIIPYEWNRVVLNAIRGIEGSDYINASYIDGYRDRRAYIAAQSPIPSTVEDFWRMLWDQHCGVVIVLNQPHE---DKSHIYWPINKSIRYQFFVVDPVVEYNMPNYILREFKVTDARDGEFRALRQFQFTQWPNHGCPKESESILDFIRQVHKTKEQFGHMEPMVIHCNTGSGRTGVFIALSIVLDRLQQESVVDMYQTVKLLHKQRIGLVQTEEQYEFCYMAVLDYLSNYE 5814
N+D C + +++P +D +++R + ++ + + P I I +L ++ LKAND L E+E+++ +FTW+ SN++ NK+KNRYANV+AYDH+ V+L PV+ +IGSDYINANYIDGY++QNAYIATQG LP+T DFWRMVWEQRS +VMMT+LEE+S IKC QYWP+RG YG + V+ +DT LA + +R F + S SEKRE++ FQFTAWPDHGVP+ TP L F+RRV++ ++ P +VHCSAGVGRTG FIV+DA LERIK EK +D++ +V+ +R QRNYMVQT+ QY FI + LLEAV GNTEV A N + ++ KL+QI + ++G E+EF +L + ++ R F+ A N N KNR+ NI+PYE RV L IRG+EGSDYINAS+IDGYR ++AYIA Q P+ T EDFWRMLW+ + +V++L + E +K H YWP +S RYQ+FVVDP+ EYNMP YILREFKVTDARDG+ R +RQFQFT WP G PK E +DFI QVHKTKEQFG P+ +HC+ G GRTGVFI LSIVL+R++ E VVD++QTVK+L QR +VQTE++Y+FCY A L+YL +++
Sbjct: 1298 NSDPRTKCLLNNAEIAPHHPTDPVEMRRINFQTPGMLNHPPIPIADLSEHTEHLKANDNLKLSQEYESVDPG--QQFTWEHSNLEVNKAKNRYANVIAYDHSRVILLPVEGIIGSDYINANYIDGYRKQNAYIATQGALPETFGDFWRMVWEQRSATVVMMTKLEEKSRIKCDQYWPSRGTETYGMIQVTLLDTIELATFCVRTFSLHKSGSSEKREVRQFQFTAWPDHGVPEYPTPFLAFLRRVKTCNPPDAGPVVVHCSAGVGRTGCFIVIDAMLERIKHEKTVDIYGHVTLMRSQRNYMVQTEDQYSFIHDALLEAVACGNTEVPARNLYTYIQKLAQIEL--GEHVTGMELEFKRLANSKAHTSR-------FISA--NLPCNKFKNRLVNIMPYESTRVCLQPIRGVEGSDYINASFIDGYRQQKAYIATQGPLAETTEDFWRMLWENNSTIVVMLTKLREMGREKCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDARDGQSRTVRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKEQFGQDGPISVHCSAGVGRTGVFITLSIVLERMRYEGVVDIFQTVKMLRTQRPAMVQTEDEYQFCYQAALEYLGSFD 1910 HSP 2 Score: 202.216 bits (513), Expect = 3.194e-51 Identity = 104/262 (39.69%), Postives = 152/262 (58.02%), Query Frame = 1
Query: 5092 NQAVNMTKNRVRNIIPYEWNRVVLNAIRGIEGSDYINASYIDGYRDRRAYIAAQSPIPSTVEDFWRMLWDQHCGVVIVLNQPHEDKSHI----YWPINKSIRYQFFVVDPVVEYNMPNYILREFKVTDARDGEFRALRQFQFTQWPNHGCPKESESILDFIRQVHKTKEQFGHMEPMVIHCNTGSGRTGVFIALSIVLDRLQQESVVDMYQTVKLLHKQRIGLVQTEEQYEFCYMAVLDYLSNYEKILEKSHLY*TYQDLSE 5865
N VN KNR N+I Y+ +RV+L + GI GSDYINA+YIDGYR + AYIA Q +P T DFWRM+W+Q V+++ + E+KS I YWP + Y V + + + +R F + + E R +RQFQFT WP+HG P+ L F+R+V P+V+HC+ G GRTG FI + +L+R++ E VD+Y V L+ QR +VQTE+QY F + A+L+ ++ + +LY Q L++
Sbjct: 1378 NLEVNKAKNRYANVIAYDHSRVILLPVEGIIGSDYINANYIDGYRKQNAYIATQGALPETFGDFWRMVWEQRSATVVMMTK-LEEKSRIKCDQYWPSRGTETYGMIQVTLLDTIELATFCVRTFSLHKSGSSEKREVRQFQFTAWPDHGVPEYPTPFLAFLRRVKTCNPP--DAGPVVVHCSAGVGRTGCFIVIDAMLERIKHEKTVDIYGHVTLMRSQRNYMVQTEDQYSFIHDALLEAVACGNTEVPARNLYTYIQKLAQ 1636 HSP 3 Score: 145.591 bits (366), Expect = 4.970e-34 Identity = 254/1096 (23.18%), Postives = 407/1096 (37.14%), Query Frame = 1
Query: 370 LACSSTGHPVPSISW-----KINESPIEELKSPLKKLQNPPRIFSIKNYQNSVLVITQLIESDSNSVLICEAENNAGFDSRQQQLKVISTETDIPSGFPVFQNNFFPIIKPYNSNVTLVCQAYGNPPPLIQWFKNYELINESFT--KIKILND------GNLLLVQVTREDKGIYHCQAQNTNGLRLSDPSTLDITSYPISPNSLII----ERFASDNVEIS------------WRSGLNDVTEQENFILHYREVPENITEKQIMSKFVYLTISEKKSIYKYNLKDLFPFTTYCIWMESENPLGVSPPTIALTVKTLPTSPQLSPRSITATSISNTAILVAWRPPERKFGKFKYYQIIYTNNDGFLPQHWRQFAVKDDNVMLTHLIAS----ELYHIRVKIVNEIGHGPLSKTISIKTIAGTLSQCP-DFKITEIFQSHIKLQWGTPDPVKLFKLIQYNLLCWDVRLKIVNATAKSSTLFPILNHNLSMNEMEYVLYLKNEKEIKCRLSAINSDGKG-MPTEIQASTVNKGVNYQNL-IHIDKIGSTYITFQWRPPSKFSFDYFLWIYQIFDSEKLDRAVKLPKIKINISDSASAENGWFVYNYTNAFSSSRYILGLRYLCRDSTDILREYVHRSDLVSTMKSVPSDSPKDLVVKEIDSNSALVSWKPLDQVHSNGIITHYEVRYYAPKKEESTERFIN--VSETSAILSNL--KYFHYVIYVRAFTKVGGGSWSNPKNYYRQNLEEFPIPTTIKGERKSETEINISWELPVLSEKNLAHAAIEGFIILYAPVE----SSPKWIKYTV---------QSKNLSAVIKGLEPDLRYQFQIAATNYAGFNGNFSEIVQEMPKNFPNLNLKTVPDLRCSVQSSNRLKVEWSSPSISTDLLKFEIRYSGNLSYITEIGLKKSEFIDMESKSVNFETLVNRYDVTLENLQSNALYKIAVRAIYQNKELYESHRETTCDTMPAVPNLVKPPIIVGLDEEKSKVIIKLHRCSQRNGKIS-YYFVIVAAFQGNKNQQISFQEDTESYTFMELSVNT------RSNNAKG--------EYIAIMKD--INDIFKVSGKDHSSVLL 3447
C +TG P P ++W K+N E ++ +VL I L +V C A+N G + +L V+ E +PSGFP + T++C A GNP P I WFK++ ++ + + +IK L G L + D+G Y C A N+ G+R S P+ L + ++P I+ E NV I+ W G D+T +++ V N+ E LT N+K+ +T C+ M S LGV +TVK+LP +P + T + T+I V W YY I Y + P + +K+D + I Y I V VN IG GP S+ + +T + P + + + + + +QW P ++ N R+ + + + L +N+ + + + L + R+ A S G G + IQ T +GV Q + + T I W PP + S + Y+ + R P + N +++ + S + LG L DI TM+S PS P+++ S + LVSW P NG++ Y VRY A +++ + + +T+ IL K+ Y I V A T+VG G S P P ++ E + T I + W PV +N H I G+ + Y +E S IK + + VI GL+P+ Y +AA G + P PDL S L VEW P S + L Y + G + + ++ F L +Y T + + ++K+AV+ E DT P L++ I+ + + + + L ++RNG I+ Y A K Q+I S+ +L+ NT R++ KG +Y + D + FKV +SVLL
Sbjct: 52 FVCQATGDPKPRVTWNKRGKKVNSQRFETIE--------------FDEGAGAVLRIQPLRTPRDENVYECVAQNVHGEEVVSAKLTVLR-EDQLPSGFPNIDMGPQLKVVERTRTATMLCAASGNPDPEITWFKDFLPVDPASSNGRIKQLRSENTPIRGALQIENSEETDQGKYECVATNSAGVRYSSPANLYVRVRRVAPRFSILPVSHEIMPGGNVNITCVAVGSPMPYVKWMVGAEDLTPEDDM-----PVGRNVLE---------LT----------NVKESANYT--CVAMSS---LGVIESVAQITVKSLPKAPG----TPVVTETTATSITVTWD--SGNPDPVSYYVIEYKSKSQDGP-----YQIKEDITTTRYSIGGLSPNSEYEIWVSAVNSIGQGPPSEPVVTRTGEQAPASAPRNVQARMLSSTTMIIQWEEP--------VEPNGQIRGYRVYYTMEPDQPVSSW--LKYNVDDSLLTTIGSLLEHETYTVRVLAFTSVGDGPLSDPIQVKT-QQGVPGQPMNFRAEAKSETSIGLTWSPPRQDSIVKYELNYREGEGGNEIRKTFDPATSYTV--EGLKPNTEYLFRLA---ARSSHGLGAWTL-----DIKER---------TMQSKPSAPPRNVKCVSSKSTTILVSWLPPPAESQNGVLAGYSVRYSALDSDDTRPKEVKDIPPQTTQILLEALEKWTVYRITVVAHTEVGPGPESPPVEIRTDEDVPSAPPRKVEVEVLNSTAIKVFWRSPV---QNRQHGQIRGYQVHYVRMENGEASGLTLIKDVMLADAQWEMDDTAEYEMVISGLQPETSYSVTVAAYTMKGDGARSKPKLVTTRGAVPGK-----PDLFVHQNSDGSLLVEWEPPRESEGHI---------LGYRLQFGRQDVMLLS----TLEFGELEKKYLATNIHKGATYVFKMAVKGRVGLSEEAVKEFIVPEDTPKGFPQLIEKGIVTSMSIQLNWLPPVL---AERNGVITKYTLAYRVAGSSEKLQEIDLPSSDNSFILTDLNPNTVYEVKIRAHTRKGPGPYSPTVQYRTFLLDQVLPKNFKVKMVTKTSVLL 1038 HSP 4 Score: 142.895 bits (359), Expect = 3.288e-33 Identity = 211/976 (21.62%), Postives = 390/976 (39.96%), Query Frame = 1
Query: 271 LINSQITFTENDEAPK----ISLIIQSPNVLLFKSMILACSSTGHPVPSISWKINESPIEELKS--PLKKL--QNPPRIFSIKNYQNSVLVITQLIESDSNSVLICEAENNAGFDSRQQQLKVISTETDIP--SGFPVFQNNFFPIIKPYNSNVTLVCQAYGNPPPLIQWFKNYELINESFTKIKILNDGNLLLVQVTREDKGIYHCQAQNTNGLRLSDPSTLDITSYPISPNSLIIERFASDNVEISWRSGLNDVTEQENFILHYREVPENITEKQIMSKFVYLTISEKKSIYKYNLKDLFPFTTYCIWMESENPLGVSPPTIALTVKTLPTSPQLSPRSITATSISNTAILVAWRPPERKFGKFKYYQIIYTNNDGFLPQHWRQFAVKDDNVMLT--HLIASELYHIRVKIVNEIGHGPLSKTISIKTIAGTLSQCPDFKITEIFQSHIKLQWGTPDPVKLFKLIQYNLLCWDVRLKIVNATAKSSTLFPILNHNLSMNEMEYVLYLKNEKEIKCRLSAINSDGKGMPT-EIQASTV-NKGVNYQNLIHIDKIGSTYITFQWRPPSKFSFDYFLWIYQIFDSEKLDRAVKLPKIKINISDSAS-----AENGWFVYNYTNAFSSSRYILGLRYLCRDSTDILREYVHRSDLVSTMKSVPSDSPKDLVVKEIDSNSALVSWKPLDQVHSNGIITHYEVRYYAPKKEESTERFI--------------NVSETSAILSNLK-YFHYVIYVRAFTKVGGGSWSNPKNYYRQNLEEFPIPTTIKGERKSETEINISWELPVLSEKNLAHAAIE---GFIILYAPVESSPKWIKYTVQSKNLSAVIKGLEPDLRYQFQIAATNYAGFNGNFSE---IVQEMPKNFPNLNLKTVPDLRCSVQSSNRLKVEWSSPSISTDLLKFEIRYSGNLSYITEIGLKKSEFIDMESKSVNFETLVNRYDVTLENLQSNALYKIAVRA 3078
++++++T D+ P I + Q V ++ + C+++G+P P I+W + P++ S +K+L +N P I +NS E C A N+AG + P S PV + P NV + C A G+P P ++W + E T + G +L ++ Y C A ++ G+ + + + + S P +P + ++ + ++ ++W SG D +++ Y+ S+ I E + +Y++ L P + Y IW+ + N +G PP+ + +T +P +PR++ A +S+T +++ W P G+ + Y++ YT W ++ V DD+++ T L+ E Y +RV +G GPLS I +KT G Q +F+ ++ I L W P + +++Y L + T P ++ V LK E RL+A +S G G T +I+ T+ +K + ST I W PP S + L Y + S LD PK +I + A W VY R T++ + T + VPS P+ + V+ ++S + V W+ Q +G I Y+V Y + E++ + + +E ++S L+ Y + V A+T G G+ S PK + P + + S+ + + WE P SE ++ ++ ++L + +E KY + + A Y F++A G + + + ++ PK FP L + + +S +++ W P ++ + + L+Y +K + ID+ S +F L +L N +Y++ +RA
Sbjct: 117 VVSAKLTVLREDQLPSGFPNIDMGPQLKVVERTRTATMLCAASGNPDPEITWFKDFLPVDPASSNGRIKQLRSENTP-IRGALQIENS--------EETDQGKYECVATNSAGVRYSSPANLYVRVRRVAPRFSILPV-SHEIMP-----GGNVNITCVAVGSPMPYVKWM----VGAEDLTPEDDMPVGRNVLELTNVKESANYTCVAMSSLGV-IESVAQITVKSLPKAPGTPVVTETTATSITVTWDSGNPDPVSY--YVIEYKS----------KSQDGPYQIKEDITTTRYSIGGLSPNSEYEIWVSAVNSIGQGPPSEPVVTRTGEQAPASAPRNVQARMLSSTTMIIQWEEPVEPNGQIRGYRVYYTMEPDQPVSSWLKYNV-DDSLLTTIGSLLEHETYTVRVLAFTSVGDGPLSDPIQVKTQQGVPGQPMNFRAEAKSETSIGLTWSPP---RQDSIVKYELNYREGE----GGNEIRKTFDPATSYT--------VEGLKPNTEYLFRLAARSSHGLGAWTLDIKERTMQSKPSAPPRNVKCVSSKSTTILVSWLPPPAESQNGVLAGYSVRYS-ALDSDDTRPKEVKDIPPQTTQILLEALEKWTVY---------------RITVVAHTEVGPGPESPPVEIRTDEDVPSAPPRKVEVEVLNSTAIKVFWRSPVQNRQHGQIRGYQVHYVRMENGEASGLTLIKDVMLADAQWEMDDTAEYEMVISGLQPETSYSVTVAAYTMKGDGARSKPKLVTTRG--AVPGKPDLFVHQNSDGSLLVEWEPPRESEGHILGYRLQFGRQDVMLLSTLEFGELEKKYLATNIHKGAT---------YVFKMAVKGRVGLSEEAVKEFIVPEDTPKGFPQL-------IEKGIVTSMSIQLNWLPPVLAE---RNGVITKYTLAYRVAGSSEKLQEIDLPSSDNSF---------ILTDLNPNTVYEVKIRA 998 HSP 5 Score: 94.7449 bits (234), Expect = 1.798e-18 Identity = 120/501 (23.95%), Postives = 212/501 (42.32%), Query Frame = 1
Query: 1126 YNLKDLFPFTTYCIWMESENPLGVSPPTIALTVKTLPTSPQLSPRSITATSISNTAILVAWRPP--ERKFGKFKYYQIIYT--NNDGFLPQHWRQFAVKDDNVMLTHLIASELYHIRVKIVNEIGHGPLSKTISIKTIAGTLSQCPDFKITEIFQS-HIKLQWGTPDPVKLFKLIQYNLLCWDVRLKIVNATAKSSTLFP---ILNHNLSMN---EMEYVLY-LKNEKEIKCRLSAINSDGKGMPTEIQASTVNKGVNYQNLIHIDKIGSTYITFQWRPPSKFSFDYFLWIYQIFDSEKLDRAVKLPKIKINISDSASAENGWFVYNY--TNAFSSSRYILGLRYLCRD--STDILREYVHRSDLVSTMKSVPSDSPK---DLVVKEI-DSNSALVSWKPLDQVHSNGIITHYEVRY-YAPKKEESTERFINVSETSAILSNLK-YFHYVIYVRAFTKVGGGSWSNPKNYYRQNLEEFPIPTTIKGERKSETEINISWELP 2562
Y ++ L P T Y + + + G+ T+ + +T+ + P PR++ S +T ILV+W PP E + G Y + Y+ ++D P+ + + ++L L +Y I V E+G GP S + I+T S P E+ S IK+ W +P + I+ + + +++ N A TL + + M+ E E V+ L+ E ++A G G ++ + T V + + + + + +W PP +SE +L + ++ ++ E G Y TN + Y+ + R S + ++E++ VP D+PK L+ K I S S ++W P NG+IT Y + Y A E+ E + S+ S IL++L Y + +RA T+ G G +S P YR L + +P K + ++T + +SWE P
Sbjct: 572 YTVEGLKPNTEYLFRLAARSSHGLGAWTLDIKERTMQSKPSAPPRNVKCVSSKSTTILVSWLPPPAESQNGVLAGYSVRYSALDSDDTRPKEVKDIPPQTTQILLEALEKWTVYRITVVAHTEVGPGPESPPVEIRTDEDVPSAPPRKVEVEVLNSTAIKVFWRSPVQNRQHGQIRGYQVHY---VRMENGEASGLTLIKDVMLADAQWEMDDTAEYEMVISGLQPETSYSVTVAAYTMKGDGARSKPKLVTTRGAVPGKPDLFVHQNSDGSLLVEWEPPR--------------ESEGHILGYRLQFGRQDVMLLSTLEFGELEKKYLATNIHKGATYVFKMAVKGRVGLSEEAVKEFI-----------VPEDTPKGFPQLIEKGIVTSMSIQLNWLPPVLAERNGVITKYTLAYRVAGSSEKLQEIDLPSSDNSFILTDLNPNTVYEVKIRAHTRKGPGPYS-PTVQYRTFLLDQVLPKNFKVKMVTKTSVLLSWEFP 1043
BLAST of Protein tyrosine phosphatase receptor type D vs. Ensembl Xenopus
Match: brdt (bromodomain, testis-specific [Source:Xenbase;Acc:XB-GENE-983868]) HSP 1 Score: 721.465 bits (1861), Expect = 0.000e+0 Identity = 338/626 (53.99%), Postives = 450/626 (71.88%), Query Frame = 1
Query: 3949 NADSVQMCQ-DGTKLSPVLVSDSIKLRIGSQKSENISDRPSISICNLYQYVTDLKANDCTLLQAEFETLNTNLDDRFTWQRSNIDSNKSKNRYANVVAYDHTSVLLTPVDDVIGSDYINANYIDGYQRQNAYIATQGPLPDTTDDFWRMVWEQRSNCIVMMTRLEERSGIKCHQYWPNRGFICYGQMIVSHIDTFVLAYYTIRLFEIRHSKYSEKREIQHFQFTAWPDHGVPKLSTPLLMFIRRVRSIGKIESCPKIVHCSAGVGRTGAFIVVDAQLERIKQEKNIDVFNYVSKIRCQRNYMVQTQAQYQFILETLLEAVEDGNTEVMACNFHAHVTKLSQIGISGSNQLSGFEMEFSKLNSLASNRGRHGVMLADFVKAAGNQAVNMTKNRVRNIIPYEWNRVVLNAIRGIEGSDYINASYIDGYRDRRAYIAAQSPIPSTVEDFWRMLWDQHCGVVIVLNQPHE---DKSHIYWPINKSIRYQFFVVDPVVEYNMPNYILREFKVTDARDGEFRALRQFQFTQWPNHGCPKESESILDFIRQVHKTKEQFGHMEPMVIHCNTGSGRTGVFIALSIVLDRLQQESVVDMYQTVKLLHKQRIGLVQTEEQYEFCYMAVLDYLSNYE 5814
N+D C + +++P +D +++R + ++ + + P I I +L ++ LKAND L E+E+++ +FTW+ SN++ NK+KNRYANV+AYDH+ V+L PV+ +IGSDYINANYIDGY++QNAYIATQG LP+T DFWRMVWEQRS +VMMT+LEE+S IKC QYWP+RG YG + V+ +DT LA + +R F + S SEKRE++ FQFTAWPDHGVP+ TP L F+RRV++ ++ P +VHCSAGVGRTG FIV+DA LERIK EK +D++ +V+ +R QRNYMVQT+ QY FI + LLEAV GNTEV A N + ++ KL+QI + ++G E+EF +L + ++ R F+ A N N KNR+ NI+PYE RV L IRG+EGSDYINAS+IDGYR ++AYIA Q P+ T EDFWRMLW+ + +V++L + E +K H YWP +S RYQ+FVVDP+ EYNMP YILREFKVTDARDG+ R +RQFQFT WP G PK E +DFI QVHKTKEQFG P+ +HC+ G GRTGVFI LSIVL+R++ E VVD++QTVK+L QR +VQTE++Y+FCY A L+YL +++
Sbjct: 1289 NSDPRTKCLLNNAEIAPHHPTDPVEMRRINFQTPGMLNHPPIPIADLSEHTEHLKANDNLKLSQEYESVDPG--QQFTWEHSNLEVNKAKNRYANVIAYDHSRVILLPVEGIIGSDYINANYIDGYRKQNAYIATQGALPETFGDFWRMVWEQRSATVVMMTKLEEKSRIKCDQYWPSRGTETYGMIQVTLLDTIELATFCVRTFSLHKSGSSEKREVRQFQFTAWPDHGVPEYPTPFLAFLRRVKTCNPPDAGPVVVHCSAGVGRTGCFIVIDAMLERIKHEKTVDIYGHVTLMRSQRNYMVQTEDQYSFIHDALLEAVACGNTEVPARNLYTYIQKLAQIEL--GEHVTGMELEFKRLANSKAHTSR-------FISA--NLPCNKFKNRLVNIMPYESTRVCLQPIRGVEGSDYINASFIDGYRQQKAYIATQGPLAETTEDFWRMLWENNSTIVVMLTKLREMGREKCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDARDGQSRTVRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKEQFGQDGPISVHCSAGVGRTGVFITLSIVLERMRYEGVVDIFQTVKMLRTQRPAMVQTEDEYQFCYQAALEYLGSFD 1901 HSP 2 Score: 202.216 bits (513), Expect = 3.403e-51 Identity = 104/262 (39.69%), Postives = 152/262 (58.02%), Query Frame = 1
Query: 5092 NQAVNMTKNRVRNIIPYEWNRVVLNAIRGIEGSDYINASYIDGYRDRRAYIAAQSPIPSTVEDFWRMLWDQHCGVVIVLNQPHEDKSHI----YWPINKSIRYQFFVVDPVVEYNMPNYILREFKVTDARDGEFRALRQFQFTQWPNHGCPKESESILDFIRQVHKTKEQFGHMEPMVIHCNTGSGRTGVFIALSIVLDRLQQESVVDMYQTVKLLHKQRIGLVQTEEQYEFCYMAVLDYLSNYEKILEKSHLY*TYQDLSE 5865
N VN KNR N+I Y+ +RV+L + GI GSDYINA+YIDGYR + AYIA Q +P T DFWRM+W+Q V+++ + E+KS I YWP + Y V + + + +R F + + E R +RQFQFT WP+HG P+ L F+R+V P+V+HC+ G GRTG FI + +L+R++ E VD+Y V L+ QR +VQTE+QY F + A+L+ ++ + +LY Q L++
Sbjct: 1369 NLEVNKAKNRYANVIAYDHSRVILLPVEGIIGSDYINANYIDGYRKQNAYIATQGALPETFGDFWRMVWEQRSATVVMMTK-LEEKSRIKCDQYWPSRGTETYGMIQVTLLDTIELATFCVRTFSLHKSGSSEKREVRQFQFTAWPDHGVPEYPTPFLAFLRRVKTCNPP--DAGPVVVHCSAGVGRTGCFIVIDAMLERIKHEKTVDIYGHVTLMRSQRNYMVQTEDQYSFIHDALLEAVACGNTEVPARNLYTYIQKLAQ 1627 HSP 3 Score: 145.206 bits (365), Expect = 6.605e-34 Identity = 254/1096 (23.18%), Postives = 407/1096 (37.14%), Query Frame = 1
Query: 370 LACSSTGHPVPSISW-----KINESPIEELKSPLKKLQNPPRIFSIKNYQNSVLVITQLIESDSNSVLICEAENNAGFDSRQQQLKVISTETDIPSGFPVFQNNFFPIIKPYNSNVTLVCQAYGNPPPLIQWFKNYELINESFT--KIKILND------GNLLLVQVTREDKGIYHCQAQNTNGLRLSDPSTLDITSYPISPNSLII----ERFASDNVEIS------------WRSGLNDVTEQENFILHYREVPENITEKQIMSKFVYLTISEKKSIYKYNLKDLFPFTTYCIWMESENPLGVSPPTIALTVKTLPTSPQLSPRSITATSISNTAILVAWRPPERKFGKFKYYQIIYTNNDGFLPQHWRQFAVKDDNVMLTHLIAS----ELYHIRVKIVNEIGHGPLSKTISIKTIAGTLSQCP-DFKITEIFQSHIKLQWGTPDPVKLFKLIQYNLLCWDVRLKIVNATAKSSTLFPILNHNLSMNEMEYVLYLKNEKEIKCRLSAINSDGKG-MPTEIQASTVNKGVNYQNL-IHIDKIGSTYITFQWRPPSKFSFDYFLWIYQIFDSEKLDRAVKLPKIKINISDSASAENGWFVYNYTNAFSSSRYILGLRYLCRDSTDILREYVHRSDLVSTMKSVPSDSPKDLVVKEIDSNSALVSWKPLDQVHSNGIITHYEVRYYAPKKEESTERFIN--VSETSAILSNL--KYFHYVIYVRAFTKVGGGSWSNPKNYYRQNLEEFPIPTTIKGERKSETEINISWELPVLSEKNLAHAAIEGFIILYAPVE----SSPKWIKYTV---------QSKNLSAVIKGLEPDLRYQFQIAATNYAGFNGNFSEIVQEMPKNFPNLNLKTVPDLRCSVQSSNRLKVEWSSPSISTDLLKFEIRYSGNLSYITEIGLKKSEFIDMESKSVNFETLVNRYDVTLENLQSNALYKIAVRAIYQNKELYESHRETTCDTMPAVPNLVKPPIIVGLDEEKSKVIIKLHRCSQRNGKIS-YYFVIVAAFQGNKNQQISFQEDTESYTFMELSVNT------RSNNAKG--------EYIAIMKD--INDIFKVSGKDHSSVLL 3447
C +TG P P ++W K+N E ++ +VL I L +V C A+N G + +L V+ E +PSGFP + T++C A GNP P I WFK++ ++ + + +IK L G L + D+G Y C A N+ G+R S P+ L + ++P I+ E NV I+ W G D+T +++ V N+ E LT N+K+ +T C+ M S LGV +TVK+LP +P + T + T+I V W YY I Y + P + +K+D + I Y I V VN IG GP S+ + +T + P + + + + + +QW P ++ N R+ + + + L +N+ + + + L + R+ A S G G + IQ T +GV Q + + T I W PP + S + Y+ + R P + N +++ + S + LG L DI TM+S PS P+++ S + LVSW P NG++ Y VRY A +++ + + +T+ IL K+ Y I V A T+VG G S P P ++ E + T I + W PV +N H I G+ + Y +E S IK + + VI GL+P+ Y +AA G + P PDL S L VEW P S + L Y + G + + ++ F L +Y T + + ++K+AV+ E DT P L++ I+ + + + + L ++RNG I+ Y A K Q+I S+ +L+ NT R++ KG +Y + D + FKV +SVLL
Sbjct: 43 FVCQATGDPKPRVTWNKRGKKVNSQRFETIE--------------FDEGAGAVLRIQPLRTPRDENVYECVAQNVHGEEVVSAKLTVLR-EDQLPSGFPNIDMGPQLKVVERTRTATMLCAASGNPDPEITWFKDFLPVDPASSNGRIKQLRSENTPIRGALQIENSEETDQGKYECVATNSAGVRYSSPANLYVRVRRVAPRFSILPVSHEIMPGGNVNITCVAVGSPMPYVKWMVGAEDLTPEDDM-----PVGRNVLE---------LT----------NVKESANYT--CVAMSS---LGVIESVAQITVKSLPKAPG----TPVVTETTATSITVTWD--SGNPDPVSYYVIEYKSKSQDGP-----YQIKEDITTTRYSIGGLSPNSEYEIWVSAVNSIGQGPPSEPVVTRTGEQAPASAPRNVQARMLSSTTMIIQWEEP--------VEPNGQIRGYRVYYTMEPDQPVSSW--LKYNVDDSLLTTIGSLLEHETYTVRVLAFTSVGDGPLSDPIQVKT-QQGVPGQPMNFRAEAKSETSIGLTWSPPRQDSIVKYELNYREGEGGNEIRKTFDPATSYTV--EGLKPNTEYLFRLA---ARSSHGLGAWTL-----DIKER---------TMQSKPSAPPRNVKCVSSKSTTILVSWLPPPAESQNGVLAGYSVRYSALDSDDTRPKEVKDIPPQTTQILLEALEKWTVYRITVVAHTEVGPGPESPPVEIRTDEDVPSAPPRKVEVEVLNSTAIKVFWRSPV---QNRQHGQIRGYQVHYVRMENGEASGLTLIKDVMLADAQWEMDDTAEYEMVISGLQPETSYSVTVAAYTMKGDGARSKPKLVTTRGAVPGK-----PDLFVHQNSDGSLLVEWEPPRESEGHI---------LGYRLQFGRQDVMLLS----TLEFGELEKKYLATNIHKGATYVFKMAVKGRVGLSEEAVKEFIVPEDTPKGFPQLIEKGIVTSMSIQLNWLPPVL---AERNGVITKYTLAYRVAGSSEKLQEIDLPSSDNSFILTDLNPNTVYEVKIRAHTRKGPGPYSPTVQYRTFLLDQVLPKNFKVKMVTKTSVLL 1029 HSP 4 Score: 142.51 bits (358), Expect = 4.959e-33 Identity = 211/976 (21.62%), Postives = 390/976 (39.96%), Query Frame = 1
Query: 271 LINSQITFTENDEAPK----ISLIIQSPNVLLFKSMILACSSTGHPVPSISWKINESPIEELKS--PLKKL--QNPPRIFSIKNYQNSVLVITQLIESDSNSVLICEAENNAGFDSRQQQLKVISTETDIP--SGFPVFQNNFFPIIKPYNSNVTLVCQAYGNPPPLIQWFKNYELINESFTKIKILNDGNLLLVQVTREDKGIYHCQAQNTNGLRLSDPSTLDITSYPISPNSLIIERFASDNVEISWRSGLNDVTEQENFILHYREVPENITEKQIMSKFVYLTISEKKSIYKYNLKDLFPFTTYCIWMESENPLGVSPPTIALTVKTLPTSPQLSPRSITATSISNTAILVAWRPPERKFGKFKYYQIIYTNNDGFLPQHWRQFAVKDDNVMLT--HLIASELYHIRVKIVNEIGHGPLSKTISIKTIAGTLSQCPDFKITEIFQSHIKLQWGTPDPVKLFKLIQYNLLCWDVRLKIVNATAKSSTLFPILNHNLSMNEMEYVLYLKNEKEIKCRLSAINSDGKGMPT-EIQASTV-NKGVNYQNLIHIDKIGSTYITFQWRPPSKFSFDYFLWIYQIFDSEKLDRAVKLPKIKINISDSAS-----AENGWFVYNYTNAFSSSRYILGLRYLCRDSTDILREYVHRSDLVSTMKSVPSDSPKDLVVKEIDSNSALVSWKPLDQVHSNGIITHYEVRYYAPKKEESTERFI--------------NVSETSAILSNLK-YFHYVIYVRAFTKVGGGSWSNPKNYYRQNLEEFPIPTTIKGERKSETEINISWELPVLSEKNLAHAAIE---GFIILYAPVESSPKWIKYTVQSKNLSAVIKGLEPDLRYQFQIAATNYAGFNGNFSE---IVQEMPKNFPNLNLKTVPDLRCSVQSSNRLKVEWSSPSISTDLLKFEIRYSGNLSYITEIGLKKSEFIDMESKSVNFETLVNRYDVTLENLQSNALYKIAVRA 3078
++++++T D+ P I + Q V ++ + C+++G+P P I+W + P++ S +K+L +N P I +NS E C A N+AG + P S PV + P NV + C A G+P P ++W + E T + G +L ++ Y C A ++ G+ + + + + S P +P + ++ + ++ ++W SG D +++ Y+ S+ I E + +Y++ L P + Y IW+ + N +G PP+ + +T +P +PR++ A +S+T +++ W P G+ + Y++ YT W ++ V DD+++ T L+ E Y +RV +G GPLS I +KT G Q +F+ ++ I L W P + +++Y L + T P ++ V LK E RL+A +S G G T +I+ T+ +K + ST I W PP S + L Y + S LD PK +I + A W VY R T++ + T + VPS P+ + V+ ++S + V W+ Q +G I Y+V Y + E++ + + +E ++S L+ Y + V A+T G G+ S PK + P + + S+ + + WE P SE ++ ++ ++L + +E KY + + A Y F++A G + + + ++ PK FP L + + +S +++ W P ++ + + L+Y +K + ID+ S +F L +L N +Y++ +RA
Sbjct: 108 VVSAKLTVLREDQLPSGFPNIDMGPQLKVVERTRTATMLCAASGNPDPEITWFKDFLPVDPASSNGRIKQLRSENTP-IRGALQIENS--------EETDQGKYECVATNSAGVRYSSPANLYVRVRRVAPRFSILPV-SHEIMP-----GGNVNITCVAVGSPMPYVKWM----VGAEDLTPEDDMPVGRNVLELTNVKESANYTCVAMSSLGV-IESVAQITVKSLPKAPGTPVVTETTATSITVTWDSGNPDPVSY--YVIEYKS----------KSQDGPYQIKEDITTTRYSIGGLSPNSEYEIWVSAVNSIGQGPPSEPVVTRTGEQAPASAPRNVQARMLSSTTMIIQWEEPVEPNGQIRGYRVYYTMEPDQPVSSWLKYNV-DDSLLTTIGSLLEHETYTVRVLAFTSVGDGPLSDPIQVKTQQGVPGQPMNFRAEAKSETSIGLTWSPP---RQDSIVKYELNYREGE----GGNEIRKTFDPATSYT--------VEGLKPNTEYLFRLAARSSHGLGAWTLDIKERTMQSKPSAPPRNVKCVSSKSTTILVSWLPPPAESQNGVLAGYSVRYS-ALDSDDTRPKEVKDIPPQTTQILLEALEKWTVY---------------RITVVAHTEVGPGPESPPVEIRTDEDVPSAPPRKVEVEVLNSTAIKVFWRSPVQNRQHGQIRGYQVHYVRMENGEASGLTLIKDVMLADAQWEMDDTAEYEMVISGLQPETSYSVTVAAYTMKGDGARSKPKLVTTRG--AVPGKPDLFVHQNSDGSLLVEWEPPRESEGHILGYRLQFGRQDVMLLSTLEFGELEKKYLATNIHKGAT---------YVFKMAVKGRVGLSEEAVKEFIVPEDTPKGFPQL-------IEKGIVTSMSIQLNWLPPVLAE---RNGVITKYTLAYRVAGSSEKLQEIDLPSSDNSF---------ILTDLNPNTVYEVKIRA 989 HSP 5 Score: 93.9745 bits (232), Expect = 2.901e-18 Identity = 120/501 (23.95%), Postives = 212/501 (42.32%), Query Frame = 1
Query: 1126 YNLKDLFPFTTYCIWMESENPLGVSPPTIALTVKTLPTSPQLSPRSITATSISNTAILVAWRPP--ERKFGKFKYYQIIYT--NNDGFLPQHWRQFAVKDDNVMLTHLIASELYHIRVKIVNEIGHGPLSKTISIKTIAGTLSQCPDFKITEIFQS-HIKLQWGTPDPVKLFKLIQYNLLCWDVRLKIVNATAKSSTLFP---ILNHNLSMN---EMEYVLY-LKNEKEIKCRLSAINSDGKGMPTEIQASTVNKGVNYQNLIHIDKIGSTYITFQWRPPSKFSFDYFLWIYQIFDSEKLDRAVKLPKIKINISDSASAENGWFVYNY--TNAFSSSRYILGLRYLCRD--STDILREYVHRSDLVSTMKSVPSDSPK---DLVVKEI-DSNSALVSWKPLDQVHSNGIITHYEVRY-YAPKKEESTERFINVSETSAILSNLKYFH-YVIYVRAFTKVGGGSWSNPKNYYRQNLEEFPIPTTIKGERKSETEINISWELP 2562
Y ++ L P T Y + + + G+ T+ + +T+ + P PR++ S +T ILV+W PP E + G Y + Y+ ++D P+ + + ++L L +Y I V E+G GP S + I+T S P E+ S IK+ W +P + I+ + + +++ N A TL + + M+ E E V+ L+ E ++A G G ++ + T V + + + + + +W PP +SE +L + ++ ++ E G Y TN + Y+ + R S + ++E++ VP D+PK L+ K I S S ++W P NG+IT Y + Y A E+ E + S+ S IL++L Y + +RA T+ G G +S P YR L + +P K + ++T + +SWE P
Sbjct: 563 YTVEGLKPNTEYLFRLAARSSHGLGAWTLDIKERTMQSKPSAPPRNVKCVSSKSTTILVSWLPPPAESQNGVLAGYSVRYSALDSDDTRPKEVKDIPPQTTQILLEALEKWTVYRITVVAHTEVGPGPESPPVEIRTDEDVPSAPPRKVEVEVLNSTAIKVFWRSPVQNRQHGQIRGYQVHY---VRMENGEASGLTLIKDVMLADAQWEMDDTAEYEMVISGLQPETSYSVTVAAYTMKGDGARSKPKLVTTRGAVPGKPDLFVHQNSDGSLLVEWEPPR--------------ESEGHILGYRLQFGRQDVMLLSTLEFGELEKKYLATNIHKGATYVFKMAVKGRVGLSEEAVKEFI-----------VPEDTPKGFPQLIEKGIVTSMSIQLNWLPPVLAERNGVITKYTLAYRVAGSSEKLQEIDLPSSDNSFILTDLNPNTVYEVKIRAHTRKGPGPYS-PTVQYRTFLLDQVLPKNFKVKMVTKTSVLLSWEFP 1034
BLAST of Protein tyrosine phosphatase receptor type D vs. Ensembl Xenopus
Match: brdt (bromodomain, testis-specific [Source:Xenbase;Acc:XB-GENE-983868]) HSP 1 Score: 720.694 bits (1859), Expect = 0.000e+0 Identity = 338/626 (53.99%), Postives = 450/626 (71.88%), Query Frame = 1
Query: 3949 NADSVQMCQ-DGTKLSPVLVSDSIKLRIGSQKSENISDRPSISICNLYQYVTDLKANDCTLLQAEFETLNTNLDDRFTWQRSNIDSNKSKNRYANVVAYDHTSVLLTPVDDVIGSDYINANYIDGYQRQNAYIATQGPLPDTTDDFWRMVWEQRSNCIVMMTRLEERSGIKCHQYWPNRGFICYGQMIVSHIDTFVLAYYTIRLFEIRHSKYSEKREIQHFQFTAWPDHGVPKLSTPLLMFIRRVRSIGKIESCPKIVHCSAGVGRTGAFIVVDAQLERIKQEKNIDVFNYVSKIRCQRNYMVQTQAQYQFILETLLEAVEDGNTEVMACNFHAHVTKLSQIGISGSNQLSGFEMEFSKLNSLASNRGRHGVMLADFVKAAGNQAVNMTKNRVRNIIPYEWNRVVLNAIRGIEGSDYINASYIDGYRDRRAYIAAQSPIPSTVEDFWRMLWDQHCGVVIVLNQPHE---DKSHIYWPINKSIRYQFFVVDPVVEYNMPNYILREFKVTDARDGEFRALRQFQFTQWPNHGCPKESESILDFIRQVHKTKEQFGHMEPMVIHCNTGSGRTGVFIALSIVLDRLQQESVVDMYQTVKLLHKQRIGLVQTEEQYEFCYMAVLDYLSNYE 5814
N+D C + +++P +D +++R + ++ + + P I I +L ++ LKAND L E+E+++ +FTW+ SN++ NK+KNRYANV+AYDH+ V+L PV+ +IGSDYINANYIDGY++QNAYIATQG LP+T DFWRMVWEQRS +VMMT+LEE+S IKC QYWP+RG YG + V+ +DT LA + +R F + S SEKRE++ FQFTAWPDHGVP+ TP L F+RRV++ ++ P +VHCSAGVGRTG FIV+DA LERIK EK +D++ +V+ +R QRNYMVQT+ QY FI + LLEAV GNTEV A N + ++ KL+QI + ++G E+EF +L + ++ R F+ A N N KNR+ NI+PYE RV L IRG+EGSDYINAS+IDGYR ++AYIA Q P+ T EDFWRMLW+ + +V++L + E +K H YWP +S RYQ+FVVDP+ EYNMP YILREFKVTDARDG+ R +RQFQFT WP G PK E +DFI QVHKTKEQFG P+ +HC+ G GRTGVFI LSIVL+R++ E VVD++QTVK+L QR +VQTE++Y+FCY A L+YL +++
Sbjct: 1281 NSDPRTKCLLNNAEIAPHHPTDPVEMRRINFQTPGMLNHPPIPIADLSEHTEHLKANDNLKLSQEYESVDPG--QQFTWEHSNLEVNKAKNRYANVIAYDHSRVILLPVEGIIGSDYINANYIDGYRKQNAYIATQGALPETFGDFWRMVWEQRSATVVMMTKLEEKSRIKCDQYWPSRGTETYGMIQVTLLDTIELATFCVRTFSLHKSGSSEKREVRQFQFTAWPDHGVPEYPTPFLAFLRRVKTCNPPDAGPVVVHCSAGVGRTGCFIVIDAMLERIKHEKTVDIYGHVTLMRSQRNYMVQTEDQYSFIHDALLEAVACGNTEVPARNLYTYIQKLAQIEL--GEHVTGMELEFKRLANSKAHTSR-------FISA--NLPCNKFKNRLVNIMPYESTRVCLQPIRGVEGSDYINASFIDGYRQQKAYIATQGPLAETTEDFWRMLWENNSTIVVMLTKLREMGREKCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDARDGQSRTVRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKEQFGQDGPISVHCSAGVGRTGVFITLSIVLERMRYEGVVDIFQTVKMLRTQRPAMVQTEDEYQFCYQAALEYLGSFD 1893 HSP 2 Score: 201.83 bits (512), Expect = 3.506e-51 Identity = 104/262 (39.69%), Postives = 152/262 (58.02%), Query Frame = 1
Query: 5092 NQAVNMTKNRVRNIIPYEWNRVVLNAIRGIEGSDYINASYIDGYRDRRAYIAAQSPIPSTVEDFWRMLWDQHCGVVIVLNQPHEDKSHI----YWPINKSIRYQFFVVDPVVEYNMPNYILREFKVTDARDGEFRALRQFQFTQWPNHGCPKESESILDFIRQVHKTKEQFGHMEPMVIHCNTGSGRTGVFIALSIVLDRLQQESVVDMYQTVKLLHKQRIGLVQTEEQYEFCYMAVLDYLSNYEKILEKSHLY*TYQDLSE 5865
N VN KNR N+I Y+ +RV+L + GI GSDYINA+YIDGYR + AYIA Q +P T DFWRM+W+Q V+++ + E+KS I YWP + Y V + + + +R F + + E R +RQFQFT WP+HG P+ L F+R+V P+V+HC+ G GRTG FI + +L+R++ E VD+Y V L+ QR +VQTE+QY F + A+L+ ++ + +LY Q L++
Sbjct: 1361 NLEVNKAKNRYANVIAYDHSRVILLPVEGIIGSDYINANYIDGYRKQNAYIATQGALPETFGDFWRMVWEQRSATVVMMTK-LEEKSRIKCDQYWPSRGTETYGMIQVTLLDTIELATFCVRTFSLHKSGSSEKREVRQFQFTAWPDHGVPEYPTPFLAFLRRVKTCNPP--DAGPVVVHCSAGVGRTGCFIVIDAMLERIKHEKTVDIYGHVTLMRSQRNYMVQTEDQYSFIHDALLEAVACGNTEVPARNLYTYIQKLAQ 1619 HSP 3 Score: 159.073 bits (401), Expect = 4.606e-38 Identity = 252/1081 (23.31%), Postives = 409/1081 (37.84%), Query Frame = 1
Query: 370 LACSSTGHPVPSISW-----KINESPIEELKSPLKKLQNPPRIFSIKNYQNSVLVITQLIESDSNSVLICEAENNAGFDSRQQQLKVISTETDIPSGFPVFQNNFFPIIKPYNSNVTLVCQAYGNPPPLIQWFKNYELINESFT--KIKILNDGNLLLVQVTREDKGIYHCQAQNTNGLRLSDPSTLDITSYPISPNSLII----ERFASDNVEIS------------WRSGLNDVTEQENFILHYREVPENITEKQIMSKFVYLTISEKKSIYKYNLKDLFPFTTYCIWMESENPLGVSPPTIALTVKTLPTSPQLSPRSITATSISNTAILVAWRPPERKFGKFKYYQIIYTNNDGFLPQHWRQFAVKDDNVMLTHLIAS----ELYHIRVKIVNEIGHGPLSKTISIKTIAGTLSQCP-DFKITEIFQSHIKLQWGTPDPVKLFKLIQYNLLCWDVRLKIVNATAKSSTLFPILNHNLSMNEMEYVLYLKNEKEIKCRLSAINSDGKG-MPTEIQASTVNKGVNYQNL-IHIDKIGSTYITFQWRPPSKFSFDYFLWIYQIFDSEKLDRAVKLPKIKINISDSASAENGWFVYNYTNAFSSSRYILGLRYLCRDSTDILREYVHRSDLVSTMKSVPSDSPKDLVVKEIDSNSALVSWKPLDQVHSNGIITHYEVRYYAPKKEESTERFIN--VSETSAILSNL--KYFHYVIYVRAFTKVGGGSWSNPKNYYRQNLEEFPIPTTIKGERKSETEINISWELPVLSEKNLAHAAIEGFIILYAPVE----SSPKWIKYTVQSKNLSAVIKGLEPDLRYQFQIAATNYAGFNGNFSEIVQEMPKNFPNLNLKTVPDLRCSVQSSNRLKVEWSSPSISTDLLKFEIRYSGNLSYITEIGLKKSEFIDMESKSVNFETLVNRYDVTLENLQSNALYKIAVRAIYQNKELYESHRETTCDTMPAVPNLVKPPIIVGLDEEKSKVIIKLHRCSQRNGKIS-YYFVIVAAFQGNKNQQISFQEDTESYTFMELSVNT------RSNNAKG--------EYIAIMKD--INDIFKVSGKDHSSVLL 3447
C +TG P P ++W K+N E ++ +VL I L +V C A+N G + +L V+ E +PSGFP + T++C A GNP P I WFK++ ++ + + +IK L G L + D+G Y C A N+ G+R S P+ L + ++P I+ E NV I+ W G D+T +++ V N+ E LT N+K+ +T C+ M S LGV +TVK+LP +P + T + T+I V W YY I Y + P + +K+D + I Y I V VN IG GP S+ + +T + P + + + + + +QW P ++ N R+ + + + L +N+ + + + L + R+ A S G G + IQ T +GV Q + + T I W PP + S + Y+ + ++ D A++ Y ++ Y+ R R S + + + TM+S PS P+++ S + LVSW P NG++ Y VRY A +++ + + +T+ IL K+ Y I V A T+VG G S P P ++ E + T I + W PV +N H I G+ + Y +E S IK + + VI GL+P+ Y +AA G + P PDL S L VEW P S + L Y + G + + ++ F L +Y T + + ++K+AV+ E DT P L++ I+ + + + + L ++RNG I+ Y A K Q+I S+ +L+ NT R++ KG +Y + D + FKV +SVLL
Sbjct: 52 FVCQATGDPKPRVTWNKRGKKVNSQRFETIE--------------FDEGAGAVLRIQPLRTPRDENVYECVAQNVHGEEVVSAKLTVLR-EDQLPSGFPNIDMGPQLKVVERTRTATMLCAASGNPDPEITWFKDFLPVDPASSNGRIKQLRSGALQIENSEETDQGKYECVATNSAGVRYSSPANLYVRVRRVAPRFSILPVSHEIMPGGNVNITCVAVGSPMPYVKWMVGAEDLTPEDDM-----PVGRNVLE---------LT----------NVKESANYT--CVAMSS---LGVIESVAQITVKSLPKAPG----TPVVTETTATSITVTWD--SGNPDPVSYYVIEYKSKSQDGP-----YQIKEDITTTRYSIGGLSPNSEYEIWVSAVNSIGQGPPSEPVVTRTGEQAPASAPRNVQARMLSSTTMIIQWEEP--------VEPNGQIRGYRVYYTMEPDQPVSSW--LKYNVDDSLLTTIGSLLEHETYTVRVLAFTSVGDGPLSDPIQVKT-QQGVPGQPMNFRAEAKSETSIGLTWSPPRQDSIVKYELNYREGEGGN----------EVRTFDPATS------YTVEGLKPNTEYL--FRLAARSSHGLGAWTLDIKE--RTMQSKPSAPPRNVKCVSSKSTTILVSWLPPPAESQNGVLAGYSVRYSALDSDDTRPKEVKDIPPQTTQILLEALEKWTVYRITVVAHTEVGPGPESPPVEIRTDEDVPSAPPRKVEVEVLNSTAIKVFWRSPV---QNRQHGQIRGYQVHYVRMENGEASGLTLIKDVMLADAQEMVISGLQPETSYSVTVAAYTMKGDGARSKPKLVTTRGAVPGK-----PDLFVHQNSDGSLLVEWEPPRESEGHI---------LGYRLQFGRQDVMLLS----TLEFGELEKKYLATNIHKGATYVFKMAVKGRVGLSEEAVKEFIVPEDTPKGFPQLIEKGIVTSMSIQLNWLPPVL---AERNGVITKYTLAYRVAGSSEKLQEIDLPSSDNSFILTDLNPNTVYEVKIRAHTRKGPGPYSPTVQYRTFLLDQVLPKNFKVKMVTKTSVLL 1022 HSP 4 Score: 150.214 bits (378), Expect = 2.434e-35 Identity = 207/963 (21.50%), Postives = 389/963 (40.39%), Query Frame = 1
Query: 271 LINSQITFTENDEAPK----ISLIIQSPNVLLFKSMILACSSTGHPVPSISWKINESPIEELKSPLKKLQNPPRIFSIKNYQNSVLVITQLIESDSNSVLICEAENNAGFDSRQQQLKVISTETDIP--SGFPVFQNNFFPIIKPYNSNVTLVCQAYGNPPPLIQWFKNYELINESFTKIKILNDGNLLLVQVTREDKGIYHCQAQNTNGLRLSDPSTLDITSYPISPNSLIIERFASDNVEISWRSGLNDVTEQENFILHYREVPENITEKQIMSKFVYLTISEKKSIYKYNLKDLFPFTTYCIWMESENPLGVSPPTIALTVKTLPTSPQLSPRSITATSISNTAILVAWRPPERKFGKFKYYQIIYTNNDGFLPQHWRQFAVKDDNVMLT--HLIASELYHIRVKIVNEIGHGPLSKTISIKTIAGTLSQCPDFKITEIFQSHIKLQWGTPDPVKLFKLIQYNLLCWDVRLKIVNATAKSSTLFPILNHNLSMNEMEYVLYLKNEKEIKCRLSAINSDGKGMPT-EIQASTV-NKGVNYQNLIHIDKIGSTYITFQWRPPSKFSFDYFLWIYQIFDSEKLDRAVKLPKIKINISDSAS-----AENGWFVYNYTNAFSSSRYILGLRYLCRDSTDILREYVHRSDLVSTMKSVPSDSPKDLVVKEIDSNSALVSWKPLDQVHSNGIITHYEVRYYAPKKEEST-----ERFINVSETSAILSNLK-YFHYVIYVRAFTKVGGGSWSNPKNYYRQNLEEFPIPTTIKGERKSETEINISWELPVLSEKNLAHAAIE---GFIILYAPVESSPKWIKYTVQSKNLSAVIKGLEPDLRYQFQIAATNYAGFNGNFSE---IVQEMPKNFPNLNLKTVPDLRCSVQSSNRLKVEWSSPSISTDLLKFEIRYSGNLSYITEIGLKKSEFIDMESKSVNFETLVNRYDVTLENLQSNALYKIAVRA 3078
++++++T D+ P I + Q V ++ + C+++G+P P I+W + P++ S + IK ++ L I E+D C A N+AG + P S PV I P NV + C A G+P P ++W + E T + G +L ++ Y C A ++ G+ + + + + S P +P + ++ + ++ ++W SG D +++ Y+ ++ + I E + +Y++ L P + Y IW+ + N +G PP+ + +T +P +PR++ A +S+T +++ W P G+ + Y++ YT W ++ V DD+++ T L+ E Y +RV +G GPLS I +KT G Q +F+ ++ I L W P Q +++ +++ + + T P ++ V LK E RL+A +S G G T +I+ T+ +K + ST I W PP S + L Y + S LD PK +I + A W VY R T++ + T + VPS P+ + V+ ++S + V W+ Q +G I Y+V Y + E++ + + ++S L+ Y + V A+T G G+ S PK + P + + S+ + + WE P SE ++ ++ ++L + +E KY + + A Y F++A G + + + ++ PK FP L + + +S +++ W P ++ + + L+Y +K + ID+ S +F L +L N +Y++ +RA
Sbjct: 117 VVSAKLTVLREDQLPSGFPNIDMGPQLKVVERTRTATMLCAASGNPDPEITWFKDFLPVDPASSNGR----------IKQLRSGALQIENSEETDQGKYE-CVATNSAGVRYSSPANLYVRVRRVAPRFSILPVSHE-----IMP-GGNVNITCVAVGSPMPYVKWM----VGAEDLTPEDDMPVGRNVLELTNVKESANYTCVAMSSLGV-IESVAQITVKSLPKAPGTPVVTETTATSITVTWDSGNPDPVSY--YVIEYKSKSQDGPYQ----------IKEDITTTRYSIGGLSPNSEYEIWVSAVNSIGQGPPSEPVVTRTGEQAPASAPRNVQARMLSSTTMIIQWEEPVEPNGQIRGYRVYYTMEPDQPVSSWLKYNV-DDSLLTTIGSLLEHETYTVRVLAFTSVGDGPLSDPIQVKTQQGVPGQPMNFRAEAKSETSIGLTWSPPR--------QDSIVKYELNYREGEGGNEVRTFDPATSYT--------VEGLKPNTEYLFRLAARSSHGLGAWTLDIKERTMQSKPSAPPRNVKCVSSKSTTILVSWLPPPAESQNGVLAGYSVRYS-ALDSDDTRPKEVKDIPPQTTQILLEALEKWTVY---------------RITVVAHTEVGPGPESPPVEIRTDEDVPSAPPRKVEVEVLNSTAIKVFWRSPVQNRQHGQIRGYQVHYVRMENGEASGLTLIKDVMLADAQEMVISGLQPETSYSVTVAAYTMKGDGARSKPKLVTTRG--AVPGKPDLFVHQNSDGSLLVEWEPPRESEGHILGYRLQFGRQDVMLLSTLEFGELEKKYLATNIHKGAT---------YVFKMAVKGRVGLSEEAVKEFIVPEDTPKGFPQL-------IEKGIVTSMSIQLNWLPPVLAE---RNGVITKYTLAYRVAGSSEKLQEIDLPSSDNSF---------ILTDLNPNTVYEVKIRA 982 HSP 5 Score: 95.9005 bits (237), Expect = 6.312e-19 Identity = 118/494 (23.89%), Postives = 210/494 (42.51%), Query Frame = 1
Query: 1126 YNLKDLFPFTTYCIWMESENPLGVSPPTIALTVKTLPTSPQLSPRSITATSISNTAILVAWRPP--ERKFGKFKYYQIIYT--NNDGFLPQHWRQFAVKDDNVMLTHLIASELYHIRVKIVNEIGHGPLSKTISIKTIAGTLSQCPDFKITEIFQS-HIKLQWGTPDPVKLFKLIQYNLLCWDVRLKIVNATAKSSTLFPILNHNLSMNEMEYVLYLKNEKEIKCRLSAINSDGKGMPTEIQASTVNKGVNYQNLIHIDKIGSTYITFQWRPPSKFSFDYFLWIYQIFDSEKLDRAVKLPKIKINISDSASAENGWFVYNY--TNAFSSSRYILGLRYLCRD--STDILREYVHRSDLVSTMKSVPSDSPK---DLVVKEI-DSNSALVSWKPLDQVHSNGIITHYEVRY-YAPKKEESTERFINVSETSAILSNLKYFH-YVIYVRAFTKVGGGSWSNPKNYYRQNLEEFPIPTTIKGERKSETEINISWELP 2562
Y ++ L P T Y + + + G+ T+ + +T+ + P PR++ S +T ILV+W PP E + G Y + Y+ ++D P+ + + ++L L +Y I V E+G GP S + I+T S P E+ S IK+ W +P + I+ + + +++ N A TL I + L+ + + L+ E ++A G G ++ + T V + + + + + +W PP +SE +L + ++ ++ E G Y TN + Y+ + R S + ++E++ VP D+PK L+ K I S S ++W P NG+IT Y + Y A E+ E + S+ S IL++L Y + +RA T+ G G +S P YR L + +P K + ++T + +SWE P
Sbjct: 565 YTVEGLKPNTEYLFRLAARSSHGLGAWTLDIKERTMQSKPSAPPRNVKCVSSKSTTILVSWLPPPAESQNGVLAGYSVRYSALDSDDTRPKEVKDIPPQTTQILLEALEKWTVYRITVVAHTEVGPGPESPPVEIRTDEDVPSAPPRKVEVEVLNSTAIKVFWRSPVQNRQHGQIRGYQVHY---VRMENGEASGLTL--IKDVMLADAQEMVISGLQPETSYSVTVAAYTMKGDGARSKPKLVTTRGAVPGKPDLFVHQNSDGSLLVEWEPPR--------------ESEGHILGYRLQFGRQDVMLLSTLEFGELEKKYLATNIHKGATYVFKMAVKGRVGLSEEAVKEFI-----------VPEDTPKGFPQLIEKGIVTSMSIQLNWLPPVLAERNGVITKYTLAYRVAGSSEKLQEIDLPSSDNSFILTDLNPNTVYEVKIRAHTRKGPGPYS-PTVQYRTFLLDQVLPKNFKVKMVTKTSVLLSWEFP 1027
BLAST of Protein tyrosine phosphatase receptor type D vs. Ensembl Mouse
Match: Ptprs (protein tyrosine phosphatase, receptor type, S [Source:MGI Symbol;Acc:MGI:97815]) HSP 1 Score: 720.694 bits (1859), Expect = 0.000e+0 Identity = 339/635 (53.39%), Postives = 452/635 (71.18%), Query Frame = 1
Query: 3928 KSIPDLVNADS---VQMCQDGTKLSPVLVSDSIKLRIGSQKSENISDRPSISICNLYQYVTDLKANDCTLLQAEFETLNTNLDDRFTWQRSNIDSNKSKNRYANVVAYDHTSVLLTPVDDVIGSDYINANYIDGYQRQNAYIATQGPLPDTTDDFWRMVWEQRSNCIVMMTRLEERSGIKCHQYWPNRGFICYGQMIVSHIDTFVLAYYTIRLFEIRHSKYSEKREIQHFQFTAWPDHGVPKLSTPLLMFIRRVRSIGKIESCPKIVHCSAGVGRTGAFIVVDAQLERIKQEKNIDVFNYVSKIRCQRNYMVQTQAQYQFILETLLEAVEDGNTEVMACNFHAHVTKLSQIGISGSNQLSGFEMEFSKLNSLASNRGRHGVMLADFVKAAGNQAVNMTKNRVRNIIPYEWNRVVLNAIRGIEGSDYINASYIDGYRDRRAYIAAQSPIPSTVEDFWRMLWDQHCGVVIVLNQPHE---DKSHIYWPINKSIRYQFFVVDPVVEYNMPNYILREFKVTDARDGEFRALRQFQFTQWPNHGCPKESESILDFIRQVHKTKEQFGHMEPMVIHCNTGSGRTGVFIALSIVLDRLQQESVVDMYQTVKLLHKQRIGLVQTEEQYEFCYMAVLDYLSNYE 5814
K+ PD DS + + L+P D +++R + ++ + P I I ++ +++ LKAND L E+E+++ +FTW+ SN+++NK KNRYANV+AYDH+ V+L P++ ++GSDYINANY+DGY+RQNAYIATQGPLP+T DFWRMVWEQRS +VMMTRLEE+S IKC QYWPNRG YG + V+ +DT LA + +R F + + SEKRE++HFQFTAWPDHGVP+ TP L F+RRV++ ++ P +VHCSAGVGRTG FIV+DA LERIK EK +DV+ +V+ +R QRNYMVQT+ QY FI E LLEAV GNTEV A + + ++ KL+Q + ++G E+EF +L S ++ R F+ A+ N KNR+ NI+PYE +RV L IRG+EGSDYINAS+IDGYR ++AYIA Q P+ T EDFWR LW+ + +V++L + E +K H YWP +S RYQ+FVVDP+ EYNMP YILREFKVTDARDG+ R +RQFQFT WP G PK E +DFI QVHKTKEQFG P+ +HC+ G GRTGVFI LSIVL+R++ E VVD++QTVK+L QR +VQTE++Y+FC+ A L+YL +++
Sbjct: 1282 KNKPDSKRKDSEPRTKCLLNNADLAPHHPKDPVEMRRINFQTPGMLSHPPIPITDMAEHMERLKANDSLKLSQEYESIDPG--QQFTWEHSNLEANKPKNRYANVIAYDHSRVILQPLEGIMGSDYINANYVDGYRRQNAYIATQGPLPETFGDFWRMVWEQRSATVVMMTRLEEKSRIKCDQYWPNRGTETYGFIQVTLLDTMELATFCVRTFSLHKNGSSEKREVRHFQFTAWPDHGVPEYPTPFLAFLRRVKTCNPPDAGPIVVHCSAGVGRTGCFIVIDAMLERIKTEKTVDVYGHVTLMRSQRNYMVQTEDQYGFIHEALLEAVGCGNTEVPARSLYTYIQKLAQ--VEPGEHVTGMELEFKRLASSKAHTSR-------FITAS--LPCNKFKNRLVNILPYESSRVCLQPIRGVEGSDYINASFIDGYRQQKAYIATQGPLAETTEDFWRALWENNSTIVVMLTKLREMGREKCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDARDGQSRTVRQFQFTDWPEQGAPKSGEGFIDFIGQVHKTKEQFGQDGPISVHCSAGVGRTGVFITLSIVLERMRYEGVVDIFQTVKVLRTQRPAMVQTEDEYQFCFQAALEYLGSFD 1903 HSP 2 Score: 201.83 bits (512), Expect = 2.831e-51 Identity = 103/262 (39.31%), Postives = 149/262 (56.87%), Query Frame = 1
Query: 5092 NQAVNMTKNRVRNIIPYEWNRVVLNAIRGIEGSDYINASYIDGYRDRRAYIAAQSPIPSTVEDFWRMLWDQHCGVVIVLNQPHEDKSHI----YWPINKSIRYQFFVVDPVVEYNMPNYILREFKVTDARDGEFRALRQFQFTQWPNHGCPKESESILDFIRQVHKTKEQFGHMEPMVIHCNTGSGRTGVFIALSIVLDRLQQESVVDMYQTVKLLHKQRIGLVQTEEQYEFCYMAVLDYLSNYEKILEKSHLY*TYQDLSE 5865
N N KNR N+I Y+ +RV+L + GI GSDYINA+Y+DGYR + AYIA Q P+P T DFWRM+W+Q V+++ + E+KS I YWP + Y F V + + + +R F + E R +R FQFT WP+HG P+ L F+R+V P+V+HC+ G GRTG FI + +L+R++ E VD+Y V L+ QR +VQTE+QY F + A+L+ + + LY Q L++
Sbjct: 1371 NLEANKPKNRYANVIAYDHSRVILQPLEGIMGSDYINANYVDGYRRQNAYIATQGPLPETFGDFWRMVWEQRSATVVMMTR-LEEKSRIKCDQYWPNRGTETYGFIQVTLLDTMELATFCVRTFSLHKNGSSEKREVRHFQFTAWPDHGVPEYPTPFLAFLRRVKTCNPP--DAGPIVVHCSAGVGRTGCFIVIDAMLERIKTEKTVDVYGHVTLMRSQRNYMVQTEDQYGFIHEALLEAVGCGNTEVPARSLYTYIQKLAQ 1629 HSP 3 Score: 153.295 bits (386), Expect = 1.895e-36 Identity = 202/837 (24.13%), Postives = 331/837 (39.55%), Query Frame = 1
Query: 370 LACSSTGHPVPSISW-----KINESPIEELKSPLKKLQNPPRIFSIKNYQNSVLVITQLIESDSNSVLICEAENNAGFDSRQQQLKVISTETDIPSGFPVFQNNFFPIIKPYNSNVTLVCQAYGNPPPLIQWFKNYELINESFT--KIKILNDGNLLLVQVTREDKGIYHCQAQNTNGLRLSDPSTLDITSYPISPNSLII----ERFASDNVEIS------------WRSGLNDVTEQENFILHYREVPENITEKQIMSKFVYLTISEKKSIYKYNLKDLFPFTTYCIWMESENPLGVSPPTIALTVKTLPTSPQLSPRSITATSISNTAILVAWRPPERKFGKFKYYQIIYTNNDGFLPQHWRQFAVKDDNVMLTHLIAS----ELYHIRVKIVNEIGHGPLSKTISIKTIAGTLSQCP-DFKITEIFQSHIKLQWGTPDPVKLFKLIQYNLLCWDVRLKIVNATAKSSTLFPILN---HNLSMNEMEYVLYLKNEKEIKCRLSAINSDGKG-MPTEIQASTVNKGVNYQNL-IHIDKIGSTYITFQWRPPSKFSFDYFLWIYQIFDSEKLDRAVKLPKIKINISDSASAENGWFVYNYTNAFS-SSRYILGLRYLCRDSTDILREYVHRSDLVSTMKSVPSDSPKDLVVKEIDSNSALVSWKPLDQVHSNGIITHYEVRYYAPKKEESTERFIN---VSETSAILSNL-KYFHYVIYVRAFTKVGGGSWSNPKNYYRQNLEEFP--IPTTIKGERKSETEINISWELPVLSEKNLAHAAIEGFIILYAPVESS----PKWIKYTVQSKNLSAVIKGLEPDLRYQFQIAATNYAG 2748
C +TG P P ++W K+N E + +VL I L +V C A+N+ G + +L V+ E +P GFP + T++C A GNP P I WFK++ ++ S + +IK L G L + D+G Y C A N+ G+R S P+ L + ++P I+ E NV I+ W G D+T +++ V N+ E LT ++KD +T C+ M S LGV +TVK+LP +P + T + T+I V W YY I Y + P + +K+D + I Y I V VN IG GP S+++ +T + P + + + + + +QW +PV+ LI+ + + + + P+ N HN+ + + V L ++ R+ A S G G + IQ T +GV Q + + + T I W P + S + +++ D + P + D N AF ++R GL T ++R+ T+++ PS P+D+ + S + LVSW+P NG + Y VRY E+ + +N + T +L L K+ Y + A+T+VG G S+P + E+ P P ++ E + T I + W P + H I G+ + Y +E + P IK + + VI L+P+ Y +AA G
Sbjct: 52 FVCQATGDPKPRVTWNKKGKKVNSQRFETI--------------DFDESSGAVLRIQPLRTPRDENVYECVAQNSVGEITIHAKLTVLR-EDQLPPGFPNIDMGPQLKVVERTRTATMLCAASGNPDPEITWFKDFLPVDPSASNGRIKQLRSGALQIESSEETDQGKYECVATNSAGVRYSSPANLYVRVRRVAPRFSILPMSHEIMPGGNVNITCVAVGSPMPYVKWMQGAEDLTPEDDM-----PVGRNVLE---------LT----------DVKDSANYT--CVAMSS---LGVIEAVAQITVKSLPKAPG----TPVVTENTATSITVTWD--SGNPDPVSYYVIEYKSKSQDGP-----YQIKEDITTTRYSIGGLSPNSEYEIWVSAVNSIGQGPPSESVVTRTGEQAPASAPRNVQARMLSATTMIVQWE--EPVEPNGLIRGYRVYYTMEPE-----------HPVGNWQKHNVDDSLLTTVGSLLEDETYTVRVLAFTSVGDGPLSDPIQVKT-QQGVPGQPMNLRAEAKSETSIGLSWSAPRQESVIKYELLFREGDRGREVGRTFDPTTAFVVED--------LKPNTEYAFRLAARSPQGLGAF----TAVVRQ--------RTLQAKPSAPPQDVKCTSLRSTAILVSWRPPPPETHNGALVGYSVRYRPLGSEDPDPKEVNNIPPTTTQILLEALEKWTEYRVTAVAYTEVGPGPESSP--VVVRTDEDVPSAPPRKVEAEALNATAIRVLWRSPTPGRQ---HGQIRGYQVHYVRMEGAEARGPPRIKDIMLADAQEMVITNLQPETAYSITVAAYTMKG 794 HSP 4 Score: 153.295 bits (386), Expect = 2.044e-36 Identity = 197/878 (22.44%), Postives = 359/878 (40.89%), Query Frame = 1
Query: 268 VLINSQITFTENDEAPK----ISLIIQSPNVLLFKSMILACSSTGHPVPSISWKINESPIEELKSPLKKLQNPPRIFSIKNYQNSVLVITQLIESDSNSVLICEAENNAGFDSRQQQLKVISTETDIPSGFPVFQNNFFPI---IKPYNSNVTLVCQAYGNPPPLIQWFKNYELINESFTKIKILNDGNLLLVQVTREDKGIYHCQAQNTNGLRLSDPSTLDITSYPISPNSLIIERFASDNVEISWRSGLNDVTEQENFILHYREVPENITEKQIMSKFVYLTISEKKSIYKYNLKDLFPFTTYCIWMESENPLGVSPPTIALTVKTLPTSPQLSPRSITATSISNTAILVAWRPPERKFGKFKYYQIIYTNNDGFLPQHWRQFAVKDDNVMLT--HLIASELYHIRVKIVNEIGHGPLSKTISIKTIAGTLSQCPDFKITEIFQSHIKLQWGTPDPVKLFKLIQYNLLCWDV-RLKIVNATAKSSTLFPILNHNLSMNEMEYVLYLKNEKEIKCRLSAINSDGKGMPTEI--QASTVNKGVNYQNLIHIDKIGSTYITFQWRPPSKFSFDYFLWIYQI----FDSEKLDRAVKLPKIKINISDSAS-----AENGWFVYNYTNAFSSSRYILGLRYLCRDSTDILREYVHRSDLVSTMKSVPSDSPKDLVVKEIDSNSALVSWKPLDQVHSNGIITHYEVRYYAPKKEES--TERFINVSETSA---ILSNLK-YFHYVIYVRAFTKVGGGSWSNPKNYYRQN-LEEFPIPTTIKGERKSETEINISWELPVLSEKNLAHAAIEGFIILYAPVESSPKWIKYTVQSKNLSAVI-KGLEPDLRYQFQIAATN---YAGFNGNFSEIVQEMPKNFPNL 2805
+ I++++T D+ P I + Q V ++ + C+++G+P P I+W + P++ S + IK ++ L I E+D C A N+AG + P + + P+ I P NV + C A G+P P ++W + E T + G +L +D Y C A ++ G+ + + + + S P +P + ++ + ++ ++W SG D +++ Y+ S+ I E + +Y++ L P + Y IW+ + N +G PP+ ++ +T +P +PR++ A +S T ++V W P G + Y++ YT +W++ V DD+++ T L+ E Y +RV +G GPLS I +KT G Q + + ++ I L W P + +I+Y LL + R + V T +T F + + LK E RL+A + G G T + Q + K + + ST I WRPP + + L Y + SE D PK NI + + A W Y T A + + G +S+ + +V T + VPS P+ + + +++ + V W+ +G I Y+V Y + E+ R ++ A +++NL+ Y I V A+T G G+ S PK + + P T+ ++ E + WE P + A + G+ + + +++P ++ + +A KG Y F++AA I ++ P+ FP +
Sbjct: 116 ITIHAKLTVLREDQLPPGFPNIDMGPQLKVVERTRTATMLCAASGNPDPEITWFKDFLPVDPSASNGR----------IKQLRSGALQIESSEETDQGK-YECVATNSAGVRYSSPANLYVRVRRVAP------RFSILPMSHEIMP-GGNVNITCVAVGSPMPYVKWMQG----AEDLTPEDDMPVGRNVLELTDVKDSANYTCVAMSSLGV-IEAVAQITVKSLPKAPGTPVVTENTATSITVTWDSGNPDPVSY--YVIEYKS----------KSQDGPYQIKEDITTTRYSIGGLSPNSEYEIWVSAVNSIGQGPPSESVVTRTGEQAPASAPRNVQARMLSATTMIVQWEEPVEPNGLIRGYRVYYTMEPEHPVGNWQKHNV-DDSLLTTVGSLLEDETYTVRVLAFTSVGDGPLSDPIQVKTQQGVPGQPMNLRAEAKSETSIGLSWSAP---RQESVIKYELLFREGDRGREVGRTFDPTTAFVVED-------------LKPNTEYAFRLAARSPQGLGAFTAVVRQRTLQAKPSAPPQDVKCTSLRSTAILVSWRPPPPETHNGALVGYSVRYRPLGSEDPD-----PKEVNNIPPTTTQILLEALEKWTEYRVT-AVAYTEVGPG-----PESSPV---------VVRTDEDVPSAPPRKVEAEALNATAIRVLWRSPTPGRQHGQIRGYQVHYVRMEGAEARGPPRIKDIMLADAQEMVITNLQPETAYSITVAAYTMKGDGARSKPKVVVTKGAVLGRP---TLSVQQTPEGSLLARWEPPA----DAAEDPVLGYRLQFGREDAAPATLELAAWERRFAAPAHKGAT----YVFRLAARGRAGLGEEAAAALSIPEDAPRGFPQI 910 HSP 5 Score: 68.9366 bits (167), Expect = 7.461e-11 Identity = 66/265 (24.91%), Postives = 119/265 (44.91%), Query Frame = 1
Query: 2164 SDLVSTMKSVPSDSPKDLVVKEIDSNSALVSWKPLDQVHSNGIITHYEVRYYAPKKEESTERF----INVSETSAILSNLKYFHYVIYVRAFTKVGGGSWSNPKNYYRQNLEEFP-IPTTIKGERKSETEINISWELPVLSEKNLAHAAIEGFIILYAPVESSPKWIKYTVQSKNLSAVIKGLEPDLRYQFQIAATNYAGFNGNFSEIV-----QEMPKNFPNLNLKTVPDLRCSVQSSNRLKVEWSSPSISTD---LLKFEIRY 2919
S + T + P+ +P+++ + + + + +V W+ + V NG+I Y V YY + E + ++ S + + S L+ Y + V AFT VG G S+P Q + P P ++ E KSET I +SW P ++ + +L+ + + + T + V++ L+P+ Y F++AA + G G F+ +V Q P P D++C+ S + V W P T L+ + +RY
Sbjct: 403 SVVTRTGEQAPASAPRNVQARMLSATTMIVQWE--EPVEPNGLIRGYRV-YYTMEPEHPVGNWQKHNVDDSLLTTVGSLLEDETYTVRVLAFTSVGDGPLSDPIQVKTQ--QGVPGQPMNLRAEAKSETSIGLSWSAP-------RQESVIKYELLFREGDRG-REVGRTFDPTT-AFVVEDLKPNTEYAFRLAARSPQGL-GAFTAVVRQRTLQAKPSAPPQ-------DVKCTSLRSTAILVSWRPPPPETHNGALVGYSVRY 645
BLAST of Protein tyrosine phosphatase receptor type D vs. Ensembl Mouse
Match: Ptprs (protein tyrosine phosphatase, receptor type, S [Source:MGI Symbol;Acc:MGI:97815]) HSP 1 Score: 718.768 bits (1854), Expect = 0.000e+0 Identity = 339/635 (53.39%), Postives = 452/635 (71.18%), Query Frame = 1
Query: 3928 KSIPDLVNADS---VQMCQDGTKLSPVLVSDSIKLRIGSQKSENISDRPSISICNLYQYVTDLKANDCTLLQAEFETLNTNLDDRFTWQRSNIDSNKSKNRYANVVAYDHTSVLLTPVDDVIGSDYINANYIDGYQRQNAYIATQGPLPDTTDDFWRMVWEQRSNCIVMMTRLEERSGIKCHQYWPNRGFICYGQMIVSHIDTFVLAYYTIRLFEIRHSKYSEKREIQHFQFTAWPDHGVPKLSTPLLMFIRRVRSIGKIESCPKIVHCSAGVGRTGAFIVVDAQLERIKQEKNIDVFNYVSKIRCQRNYMVQTQAQYQFILETLLEAVEDGNTEVMACNFHAHVTKLSQIGISGSNQLSGFEMEFSKLNSLASNRGRHGVMLADFVKAAGNQAVNMTKNRVRNIIPYEWNRVVLNAIRGIEGSDYINASYIDGYRDRRAYIAAQSPIPSTVEDFWRMLWDQHCGVVIVLNQPHE---DKSHIYWPINKSIRYQFFVVDPVVEYNMPNYILREFKVTDARDGEFRALRQFQFTQWPNHGCPKESESILDFIRQVHKTKEQFGHMEPMVIHCNTGSGRTGVFIALSIVLDRLQQESVVDMYQTVKLLHKQRIGLVQTEEQYEFCYMAVLDYLSNYE 5814
K+ PD DS + + L+P D +++R + ++ + P I I ++ +++ LKAND L E+E+++ +FTW+ SN+++NK KNRYANV+AYDH+ V+L P++ ++GSDYINANY+DGY+RQNAYIATQGPLP+T DFWRMVWEQRS +VMMTRLEE+S IKC QYWPNRG YG + V+ +DT LA + +R F + + SEKRE++HFQFTAWPDHGVP+ TP L F+RRV++ ++ P +VHCSAGVGRTG FIV+DA LERIK EK +DV+ +V+ +R QRNYMVQT+ QY FI E LLEAV GNTEV A + + ++ KL+Q + ++G E+EF +L S ++ R F+ A+ N KNR+ NI+PYE +RV L IRG+EGSDYINAS+IDGYR ++AYIA Q P+ T EDFWR LW+ + +V++L + E +K H YWP +S RYQ+FVVDP+ EYNMP YILREFKVTDARDG+ R +RQFQFT WP G PK E +DFI QVHKTKEQFG P+ +HC+ G GRTGVFI LSIVL+R++ E VVD++QTVK+L QR +VQTE++Y+FC+ A L+YL +++
Sbjct: 876 KNKPDSKRKDSEPRTKCLLNNADLAPHHPKDPVEMRRINFQTPGMLSHPPIPITDMAEHMERLKANDSLKLSQEYESIDPG--QQFTWEHSNLEANKPKNRYANVIAYDHSRVILQPLEGIMGSDYINANYVDGYRRQNAYIATQGPLPETFGDFWRMVWEQRSATVVMMTRLEEKSRIKCDQYWPNRGTETYGFIQVTLLDTMELATFCVRTFSLHKNGSSEKREVRHFQFTAWPDHGVPEYPTPFLAFLRRVKTCNPPDAGPIVVHCSAGVGRTGCFIVIDAMLERIKTEKTVDVYGHVTLMRSQRNYMVQTEDQYGFIHEALLEAVGCGNTEVPARSLYTYIQKLAQ--VEPGEHVTGMELEFKRLASSKAHTSR-------FITAS--LPCNKFKNRLVNILPYESSRVCLQPIRGVEGSDYINASFIDGYRQQKAYIATQGPLAETTEDFWRALWENNSTIVVMLTKLREMGREKCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDARDGQSRTVRQFQFTDWPEQGAPKSGEGFIDFIGQVHKTKEQFGQDGPISVHCSAGVGRTGVFITLSIVLERMRYEGVVDIFQTVKVLRTQRPAMVQTEDEYQFCFQAALEYLGSFD 1497 HSP 2 Score: 201.83 bits (512), Expect = 2.355e-51 Identity = 103/262 (39.31%), Postives = 149/262 (56.87%), Query Frame = 1
Query: 5092 NQAVNMTKNRVRNIIPYEWNRVVLNAIRGIEGSDYINASYIDGYRDRRAYIAAQSPIPSTVEDFWRMLWDQHCGVVIVLNQPHEDKSHI----YWPINKSIRYQFFVVDPVVEYNMPNYILREFKVTDARDGEFRALRQFQFTQWPNHGCPKESESILDFIRQVHKTKEQFGHMEPMVIHCNTGSGRTGVFIALSIVLDRLQQESVVDMYQTVKLLHKQRIGLVQTEEQYEFCYMAVLDYLSNYEKILEKSHLY*TYQDLSE 5865
N N KNR N+I Y+ +RV+L + GI GSDYINA+Y+DGYR + AYIA Q P+P T DFWRM+W+Q V+++ + E+KS I YWP + Y F V + + + +R F + E R +R FQFT WP+HG P+ L F+R+V P+V+HC+ G GRTG FI + +L+R++ E VD+Y V L+ QR +VQTE+QY F + A+L+ + + LY Q L++
Sbjct: 965 NLEANKPKNRYANVIAYDHSRVILQPLEGIMGSDYINANYVDGYRRQNAYIATQGPLPETFGDFWRMVWEQRSATVVMMTR-LEEKSRIKCDQYWPNRGTETYGFIQVTLLDTMELATFCVRTFSLHKNGSSEKREVRHFQFTAWPDHGVPEYPTPFLAFLRRVKTCNPP--DAGPIVVHCSAGVGRTGCFIVIDAMLERIKTEKTVDVYGHVTLMRSQRNYMVQTEDQYGFIHEALLEAVGCGNTEVPARSLYTYIQKLAQ 1223 HSP 3 Score: 131.339 bits (329), Expect = 7.102e-30 Identity = 129/567 (22.75%), Postives = 240/567 (42.33%), Query Frame = 1
Query: 268 VLINSQITFTENDEAP----KISLIIQSPNVLLFKSMILACSSTGHPVPSISWKINESPIEELKSPLKKLQNPPRIFSIKNYQNSVLVITQLIESDSNSVLICEAENNAGFDSRQQQLKVISTETDIP--SGFPVFQNNFFPIIKPYNSNVTLVCQAYGNPPPLIQWFKNYELINESFTKIKILNDGNLLLVQVTREDKGIYHCQAQNTNGLRLSDPSTLDITSYPISPNSLIIERFASDNVEISWRSGLNDVTEQENFILHYREVPENITEKQIMSKFVYLTISEKKSIYKYNLKDLFPFTTYCIWMESENPLGVSPPTIALTVKTLPTSPQLSPRSITATSISNTAILVAWRPPERKFGKFKYYQIIYTNNDGFLPQHWRQFAVKDDNVMLT--HLIASELYHIRVKIVNEIGHGPLSKTISIKTIAGTLSQCPDFKITEIFQSHIKLQWGTPDPVKLFKLIQYNLLCWDV-RLKIVNATAKSSTLFPILNHNLSMNEMEYVLYLKNEKEIKCRLSAINSDGKGMPTEIQASTVNKGVNYQNLIHIDKIGSTYITFQWRPPSKFS 1941
+ I++++T D+ P I + Q V ++ + C+++G+P P I+W + P++ S + IK ++ L I E+D C A N+AG + P S P+ I P NV + C A G+P P ++W + E T + G +L +D Y C A ++ G+ + + + + S P +P + ++ + ++ ++W SG D +++ Y+ ++ + I E + +Y++ L P + Y IW+ + N +G PP+ ++ +T +P +PR++ A +S T ++V W P G + Y++ YT +W++ V DD+++ T L+ E Y +RV +G GPLS I +KT G Q + + ++ I L W P + +I+Y LL + R + V T +T F + + LK E RL+A + G G T + + ++ +N + I T + W P ++
Sbjct: 116 ITIHAKLTVLREDQLPPGFPNIDMGPQLKVVERTRTATMLCAASGNPDPEITWFKDFLPVDPSASNGR----------IKQLRSGALQIESSEETDQGKYE-CVATNSAGVRYSSPANLYVRVRRVAPRFSILPMSHE-----IMP-GGNVNITCVAVGSPMPYVKWMQG----AEDLTPEDDMPVGRNVLELTDVKDSANYTCVAMSSLGV-IEAVAQITVKSLPKAPGTPVVTENTATSITVTWDSGNPDPVSY--YVIEYKSKSQDGPYQ----------IKEDITTTRYSIGGLSPNSEYEIWVSAVNSIGQGPPSESVVTRTGEQAPASAPRNVQARMLSATTMIVQWEEPVEPNGLIRGYRVYYTMEPEHPVGNWQKHNV-DDSLLTTVGSLLEDETYTVRVLAFTSVGDGPLSDPIQVKTQQGVPGQPMNLRAEAKSETSIGLSWSAP---RQESVIKYELLFREGDRGREVGRTFDPTTAFVVED-------------LKPNTEYAFRLAARSPQGLGAFTAVVRQRTLQAISPKNF-KVKMIMKTSVLLSWEFPDNYN 630 HSP 4 Score: 106.686 bits (265), Expect = 2.304e-22 Identity = 163/683 (23.87%), Postives = 268/683 (39.24%), Query Frame = 1
Query: 370 LACSSTGHPVPSISW-----KINESPIEELKSPLKKLQNPPRIFSIKNYQNSVLVITQLIESDSNSVLICEAENNAGFDSRQQQLKVISTETDIPSGFPVFQNNFFPIIKPYNSNVTLVCQAYGNPPPLIQWFKNYELINESFT--KIKILNDGNLLLVQVTREDKGIYHCQAQNTNGLRLSDPSTLDITSYPISPNSLII----ERFASDNVEIS------------WRSGLNDVTEQENFILHYREVPENITEKQIMSKFVYLTISEKKSIYKYNLKDLFPFTTYCIWMESENPLGVSPPTIALTVKTLPTSPQLSPRSITATSISNTAILVAWRPPERKFGKFKYYQIIYTNNDGFLPQHWRQFAVKDDNVMLTHLIAS----ELYHIRVKIVNEIGHGPLSKTISIKTIAGTLSQCP-DFKITEIFQSHIKLQWGTPDPVKLFKLIQYNLLCWDVRLKIVNATAKSSTLFPILN---HNLSMNEMEYVLYLKNEKEIKCRLSAINSDGKG-MPTEIQASTVNKGVNYQNL-IHIDKIGSTYITFQWRPPSKFSFDYFLWIYQIFDSEKLDRAVKLPKIKINISDSASAENGWFVYNYTNAFS-SSRYILGLRYLCRDSTDILREYVHRSDLVSTMKSVPSDSPKDLVVKEIDSNSALVSWKPLDQVHSNGIITHYEVRY 2316
C +TG P P ++W K+N E + +VL I L +V C A+N+ G + +L V+ E +P GFP + T++C A GNP P I WFK++ ++ S + +IK L G L + D+G Y C A N+ G+R S P+ L + ++P I+ E NV I+ W G D+T +++ V N+ E LT ++KD +T C+ M S LGV +TVK+LP +P + T + T+I V W YY I Y + P + +K+D + I Y I V VN IG GP S+++ +T + P + + + + + +QW +PV+ LI+ + + + + P+ N HN+ + + V L ++ R+ A S G G + IQ T +GV Q + + + T I W P + S + +++ D + P + D N AF ++R GL T ++R+ T++++ SPK+ VK I S L+SW+ D +S T Y+++Y
Sbjct: 52 FVCQATGDPKPRVTWNKKGKKVNSQRFETI--------------DFDESSGAVLRIQPLRTPRDENVYECVAQNSVGEITIHAKLTVLR-EDQLPPGFPNIDMGPQLKVVERTRTATMLCAASGNPDPEITWFKDFLPVDPSASNGRIKQLRSGALQIESSEETDQGKYECVATNSAGVRYSSPANLYVRVRRVAPRFSILPMSHEIMPGGNVNITCVAVGSPMPYVKWMQGAEDLTPEDDM-----PVGRNVLE---------LT----------DVKDSANYT--CVAMSS---LGVIEAVAQITVKSLPKAPG----TPVVTENTATSITVTWD--SGNPDPVSYYVIEYKSKSQDGP-----YQIKEDITTTRYSIGGLSPNSEYEIWVSAVNSIGQGPPSESVVTRTGEQAPASAPRNVQARMLSATTMIVQW--EEPVEPNGLIRGYRVYYTMEPE-----------HPVGNWQKHNVDDSLLTTVGSLLEDETYTVRVLAFTSVGDGPLSDPIQVKT-QQGVPGQPMNLRAEAKSETSIGLSWSAPRQESVIKYELLFREGDRGREVGRTFDPTTAFVVEDLKP--------NTEYAFRLAARSPQGLGAF----TAVVRQ--------RTLQAI---SPKNFKVKMIMKTSVLLSWEFPDNYNSP---TPYKIQY 639 HSP 5 Score: 63.5438 bits (153), Expect = 3.203e-9 Identity = 66/265 (24.91%), Postives = 125/265 (47.17%), Query Frame = 1
Query: 2164 SDLVSTMKSVPSDSPKDLVVKEIDSNSALVSWKPLDQVHSNGIITHYEVRYYAPKKEESTERF----INVSETSAILSNLKYFHYVIYVRAFTKVGGGSWSNPKNYYRQNLEEFP-IPTTIKGERKSETEINISWELPVLSEKNLAHAAIEGFIILYAPVESSPKWIKYTVQSKNLSAVIKGLEPDLRYQFQIAATNYAGFNGNFSEIVQEM------PKNFPNLNLKTVPDLRCSVQSSNRLKVEWSSPSISTDLLKFEIRYSG 2925
S + T + P+ +P+++ + + + + +V W+ + V NG+I Y V YY + E + ++ S + + S L+ Y + V AFT VG G S+P Q + P P ++ E KSET I +SW P ++ + +L+ + + + T + V++ L+P+ Y F++AA + G G F+ +V++ PKNF +K + ++ SV S ++SP+ ++I+Y+G
Sbjct: 403 SVVTRTGEQAPASAPRNVQARMLSATTMIVQWE--EPVEPNGLIRGYRV-YYTMEPEHPVGNWQKHNVDDSLLTTVGSLLEDETYTVRVLAFTSVGDGPLSDPIQVKTQ--QGVPGQPMNLRAEAKSETSIGLSWSAP-------RQESVIKYELLFREGDRG-REVGRTFDPTT-AFVVEDLKPNTEYAFRLAARSPQGL-GAFTAVVRQRTLQAISPKNF---KVKMI--MKTSVLLSWEFPDNYNSPT------PYKIQYNG 641
BLAST of Protein tyrosine phosphatase receptor type D vs. Ensembl Mouse
Match: Ptprf (protein tyrosine phosphatase, receptor type, F [Source:MGI Symbol;Acc:MGI:102695]) HSP 1 Score: 718.383 bits (1853), Expect = 0.000e+0 Identity = 335/606 (55.28%), Postives = 434/606 (71.62%), Query Frame = 1
Query: 4006 SDSIKLRIGSQKSENISDRPSISICNLYQYVTDLKANDCTLLQAEFETLNTNLDDRFTWQRSNIDSNKSKNRYANVVAYDHTSVLLTPVDDVIGSDYINANYIDGYQRQNAYIATQGPLPDTTDDFWRMVWEQRSNCIVMMTRLEERSGIKCHQYWPNRGFICYGQMIVSHIDTFVLAYYTIRLFEIRHSKYSEKREIQHFQFTAWPDHGVPKLSTPLLMFIRRVRSIGKIESCPKIVHCSAGVGRTGAFIVVDAQLERIKQEKNIDVFNYVSKIRCQRNYMVQTQAQYQFILETLLEAVEDGNTEVMACNFHAHVTKLSQIGISGSNQLSGFEMEFSKLNSLASNRGRHGVMLADFVKAAGNQAVNMTKNRVRNIIPYEWNRVVLNAIRGIEGSDYINASYIDGYRDRRAYIAAQSPIPSTVEDFWRMLWDQHCGVVIVLNQPHE---DKSHIYWPINKSIRYQFFVVDPVVEYNMPNYILREFKVTDARDGEFRALRQFQFTQWPNHGCPKESESILDFIRQVHKTKEQFGHMEPMVIHCNTGSGRTGVFIALSIVLDRLQQESVVDMYQTVKLLHKQRIGLVQTEEQYEFCYMAVLDYLSNYE 5814
SD +++R + ++ + D P I I +L + LKAND E+E+++ +FTW+ SN + NK KNRYANV+AYDH+ VLLT +D V GSDYINANYIDGY++QNAYIATQGPLP+T DFWRMVWEQR+ +VMMTRLEE+S +KC QYWP RG YG + V+ +DT LA YT+R F + S SEKRE++ FQF AWPDHGVP+ TP+L F+RRV++ +++ P +VHCSAGVGRTG FIV+DA LER+K EK +D++ +V+ +R QRNYMVQT+ QY FI E LLEA G+TEV+A N +AH+ KL Q+ S ++ E+EF L + ++ R FV A N N KNR+ NI+PYE RV L IRG+EGSDYINAS++DGYR ++AYIA Q P+ + EDFWRMLW+ + ++++L + E +K H YWP +S RYQ+FVVDP+ EYNMP YILREFKVTDARDG+ R +RQFQFT WP G PK E +DFI QVHKTKEQFG P+ +HC+ G GRTGVFI LSIVL+R++ E VVDM+QTVK L QR +VQTE+QY+ CY A L+YL +++
Sbjct: 1302 SDPVEMRRLNYQTPGMRDHPPIPITDLADNIERLKANDGLKFSQEYESIDPG--QQFTWENSNSEVNKPKNRYANVIAYDHSRVLLTSIDGVPGSDYINANYIDGYRKQNAYIATQGPLPETMGDFWRMVWEQRTATVVMMTRLEEKSRVKCDQYWPVRGTETYGLIQVTLVDTVELATYTMRTFALHKSGSSEKRELRQFQFMAWPDHGVPEYPTPILAFLRRVKACNPLDAGPMVVHCSAGVGRTGCFIVIDAMLERMKHEKTVDIYGHVTCMRSQRNYMVQTEDQYVFIHEALLEAAMCGHTEVLARNLYAHIQKLGQVPPGES--VTAMELEFKLLANSKAHTSR-------FVSA--NLPCNKFKNRLVNIMPYELTRVCLQPIRGVEGSDYINASFLDGYRQQKAYIATQGPLAESTEDFWRMLWEHNSTIIVMLTKLREMGREKCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDARDGQSRTIRQFQFTDWPEQGVPKTGEGFIDFIGQVHKTKEQFGQDGPITVHCSAGVGRTGVFITLSIVLERMRYEGVVDMFQTVKTLRTQRPAMVQTEDQYQLCYRAALEYLGSFD 1894 HSP 2 Score: 161.384 bits (407), Expect = 7.019e-39 Identity = 226/964 (23.44%), Postives = 386/964 (40.04%), Query Frame = 1
Query: 277 NSQITFTENDEAPK----ISLIIQSPNVLLFKSMILACSSTGHPVPSISWKINESPIEELKSPLKKLQNPPRIFSIKNYQNSVLVITQLIESDSNSVLICEAENNAGFD-SRQQQLKVISTETDIPSGFPVFQNNFFPIIKPYNSNVTLVCQAYGNPPPLIQWFKNYELINESFTKIKILNDGN--LLLVQVTREDKGIYHCQAQNTNGLRLSDPSTLDITSYPISPNSLIIERFASDNVEISWRSGLNDVTEQENFI-LHYREVPENITEKQIMSKFVYLTISEKKSIYKYNLKDLFPFTTYCIWMESENPLGVSPPTIALTVKTLPTSPQLSPRSITATSISNTAILVAWRPPERKFGKFKYYQIIYTNNDGFLPQHWRQFAVKDDNVMLT---HLIASELYHIRVKIVNEIGHGPLSKTISIKTIAGTLSQCPDFKITEIFQSHIKLQWGTPDPVKLFKLIQYNLLCWDVRLKIVNATAKSSTLFPILNHNLSMNEMEYVLYLKNEKEIKCRLSAINSDGKGM--PT-EIQASTVNKGVNYQNLIHIDKIGSTYITFQWRPPSKFSFDYFLWIYQIFDSEKLDRAVKLPKIKINISDSASAENGWFVYNYTNAFSSSRYILGL------RYLCRDSTDILREYVHRSDLVSTMKSVPSDSPKDLVVKEIDSNSALVSWKPLDQVHSNGIITHYEVRYY-----APKKEESTERFINVSETSAILSNL-KYFHYVIYVRAFTKVGGGSWSNPKNYYRQNLEEFPIPTTIKGERKSETEINISWELPVLSEKNLAHAAIEGFIILYAPV-ESSPKWIKYTVQSKNLSAVIKGLEPDLRYQFQIAATNYAGFNGNFSEIV---QEMPKNFPNLNLKTVPDLRCSVQSSNRLKVEWSSPSISTDLLKFEIRYSGNLSYITEIGLKKSEFIDMESKSVNFETLVNRYDVTLENLQSNALYKIAVRA 3078
+++++ E D+ P I + Q V ++ + C++ G+P P ISW + P++ S + IK ++ L I ESD C A N+AG S L V P P +V L C A G P P ++W + E TK + G L L V R Y C A ++ G+ + + + + + P P L++ + +V ++W SG TE +F + YR + +++ + + +Y++ L PF+ Y + + N +G PP+ A+ +T +P PR + A +S + +LV W PPE G + Y++ YT + W + D +LT L+ Y +RV +G GP S TI +KT G +Q DF+ + I+L W P ++++Y L+ W + T P ++ L LK + +L+A + G G+ PT E + + Q + + GST + W PP S + + Y + AV K ++ D S E+ SS +LGL R R TD+ LV T + VPS P+ + V+ ++S + VSWK +G I Y+V Y P+ + + + +S L Y I V A+T G G+ S PK PT + T + + W P K L + G+ + Y E+ P I + ++ + + GL Y F++AA N AG F + + +++P FP +LR + +++ ++ W P ++ +G+++ T + + D+ S+ + + + N +TL L+ + Y I VRA
Sbjct: 119 SAKLSVLEEDQLPSGFPTIDMGPQLKVVEKGRTATMLCAAGGNPDPEISWFKDFLPVDPAASNGR----------IKQLRSGALQIESSEESDQGK-YECVATNSAGTRYSAPANLYVRVRRVAPRFSIPPSSQEVMP-----GGSVNLTCVAVGAPMPYVKWM----MGAEELTKEDEMPVGRNVLELSNVMRSAN--YTCVAISSLGM-IEATAQVTVKALPKPPIDLVVTETTATSVTLTWDSG---NTEPVSFYGIQYRAAGTDGPFQEV----------DGVASTRYSIGGLSPFSEYAFRVLAVNSIGRGPPSEAVRARTGEQAPSSPPRRVQARMLSASTMLVQWEPPEEPNGLVRGYRVYYTPDSRRPLSAWHKH--NTDAGLLTTVGSLLPGITYSLRVLAFTAVGDGPPSPTIQVKTQQGVPAQPADFQANAESDTRIQLSWLLP---PQERIVKYELVYWAAEDE---GQQHKVTFDPTSSYTLE--------DLKPDTLYHFQLAARSDLGVGVFTPTVEARTAQSTPSAPPQKVTCV-STGSTTVRVSWVPPPADSRNGIITQYSV-----AYEAVDGEDRKRHVVDGISREH------------SSWDLLGLEKWTEYRVWVRAHTDVGPGPESSPVLVRTDEDVPSGPPRKVEVEPLNSTAVHVSWKLPVPNKQHGQIRGYQVTYVRLENGEPRGQPIIQDVMLAEAQETTISGLTPETTYSITVAAYTTKGDGARSKPKVVTTTGAVPG-RPTMMVSTTAMHTAL-LQWHPP----KELP-GELLGYRLQYRRADEARPNTIDFGKDDQHFT--VTGLHKGATYVFRLAAKNRAGPGEEFEKEITTPEDVPSGFPQ-------NLRVTGLTTSTTELTWDPPVLA--------ERNGHITNYTVV------YRDINSQ-LELQNVTNDTHLTLLGLKPDTTYDIKVRA 981 HSP 3 Score: 157.147 bits (396), Expect = 1.207e-37 Identity = 243/1122 (21.66%), Postives = 413/1122 (36.81%), Query Frame = 1
Query: 235 NR*MFWIITQLVLINSQITFTENDEAPKISLIIQSPNVLLFKSMILACSSTGHPVPSISWKINESPIEELKSPLKKLQNPPRIFSIKNYQNSVLVITQLIESDSNSVLICEAENNAGFDSRQQQLKVISTETDIPSGFPVFQNNFFPIIKPYNSNVTLVCQAYGNPPPLIQWFKNYELINESFT--KIKILNDGNLLLVQVTREDKGIYHCQAQNTNGLRLSDPSTLDI------TSYPISPNSLIIERFASDNVE----------ISWRSGLNDVTEQENFILHYREVPENITE-KQIMSKFVYLTISEKKSIYKYNLKDLFPFTTYCIWMESENPLGVSPPTIALTVKTLPTSPQLSPRSITATSISNTAILVAWRPPERKFGKFKYYQIIYTNNDGFLPQHWRQFAVKDDNVMLTHLIASELYHIRVKIVNEIGHGPLSKTISIKTIAGTLSQCP-DFKITEIFQSHIKLQWGTPDPVKLFKLIQYNLLCWDVRLKIVNATAKSSTLFPILNHNLSMNEMEYVLYLKNEKEIKCRLSAINSDGKGMPTEIQASTVNKGVNYQNL-IHIDKIGSTYITFQW-RPPSKFSFDYFLWIYQIFDSEKLDRAVKLPKIKINISDSASAENGWFVYNYTNAFSSSRYILGLRYLCRDSTDILREYVHRSDLVSTMKSVPSDSPKDLVVKEIDSNSALVSWKPLDQVHSNGIITHYEVRYYAPKKEESTERFIN--VSETSA--ILSNLKYFHYVIYVRAFTKVGGGSWSNPKNYYRQNLEEFP--IPTTIKGERKSETEINISWELPVLSEKNLAHAAIEGFIILYAPVESSPKWIKYTVQSKNLS----AVIKGLEPDLRYQFQIAATNYAGFNGNFSEIVQEMPKNFPNLNLKTVPDLRCSVQSSNRLKVEWSSP-SISTDLLKFEIRYSGNLSYITEIGLKKSEFIDMESKSVNFETLVNRYDVTLENLQSNALYKIAVRAIYQNKELYESHRETTCDTMPAVPNLVKPPIIVGLDEEKSKVIIKLHRCSQRNGKISYYFVIVAAFQGNKNQQISFQEDTES--YTFMELSVNT------RSNNAKG----------EYIAIMKDINDIFKVSGKDHSSVLL 3447
R M ++ LV++ + D P + + L C +TG P P I+W +K K + + SVL I L ++ C A N+ G + +L V+ E +PSGFP + T++C A GNP P I WFK++ ++ + + +IK L G L + D+G Y C A N+ G R S P+ L + + I P+S + S N+ + W G ++T+++ V N+ E +M Y C+ + S LG+ T +TVK LP P + T + T++ + W + F Q DG + V + L Y RV VN IG GP S+ + +T S P + + S + +QW P+ + N L R+ + + + + HN + V L R+ A + G G P+ +GV Q + T I W PP + Y L + D + + P + D +Y++ A +R LG+ + V T +S PS P+ + S + VSW P NGIIT Y V Y A E+ ++ E S+ +L K+ Y ++VRA T VG G S+P + E+ P P ++ E + T +++SW+LPV N H I G+ + Y +E+ + +Q L+ I GL P+ Y +AA G V P P + S + + ++W P + +LL + ++Y ++++ + +++F + VT + + ++++A + E +E T D P ++ + GL +++ ++RNG I+ Y V+ + N Q+ Q T T + L +T R++ +KG + + + F+V+ +SVLL
Sbjct: 8 GRRMVPLVPALVMLG-LMAGAHGDSKPVFVKVPEDQTGLSGGVASFVCQATGEPKPRITW---------MKKGKKVSSQRFEVIEFDDGAGSVLRIQPLRVQRDEAIYECTATNSLGEINTSAKLSVLE-EDQLPSGFPTIDMGPQLKVVEKGRTATMLCAAGGNPDPEISWFKDFLPVDPAASNGRIKQLRSGALQIESSEESDQGKYECVATNSAGTRYSAPANLYVRVRRVAPRFSIPPSSQEVMPGGSVNLTCVAVGAPMPYVKWMMGAEELTKEDEM-----PVGRNVLELSNVMRSANYT----------------------CVAISS---LGMIEATAQVTVKALPKPPI----DLVVTETTATSVTLTWDSGNTEPVSFYGIQYRAAGTDGPFQE---VDGVASTRYSIGGLSPFSEYAFRVLAVNSIGRGPPSEAVRARTGEQAPSSPPRRVQARMLSASTMLVQWEPPE--------EPNGLVRGYRVYYTPDSRRPLSAW--HKHNTDAGLLTTVGSLLPGITYSLRVLAFTAVGDGPPSPTIQVKTQQGVPAQPADFQANAESDTRIQLSWLLPPQERIVKYELVYWAAEDEGQQHKVTFDPTSSYTLEDLKPDT----LYHFQLA---ARSDLGV--------GVFTPTVE----ARTAQSTPSAPPQKVTCVSTGSTTVRVSWVPPPADSRNGIITQYSVAYEAVDGEDRKRHVVDGISREHSSWDLLGLEKWTEYRVWVRAHTDVGPGPESSP--VLVRTDEDVPSGPPRKVEVEPLNSTAVHVSWKLPV---PNKQHGQIRGYQVTYVRLENGEPRGQPIIQDVMLAEAQETTISGLTPETTYSITVAAYTTKGDGARSKPKVVTTTGAVPGR-----PTMMVSTTAMHTALLQWHPPKELPGELLGYRLQY------------RRAD--EARPNTIDFGKDDQHFTVTGLHKGATYVFRLAAKNRAGPGEEFEKEITTPEDVPSGFPQNLR---VTGLTTSTTELTWDPPVLAERNGHITNYTVVYR----DINSQLELQNVTNDTHLTLLGLKPDTTYDIKVRAHTSKGAGPLSPSIQSRTMPVEQVFAKNFRVAAAMKTSVLL 1021 HSP 4 Score: 54.6842 bits (130), Expect = 1.734e-6 Identity = 62/295 (21.02%), Postives = 121/295 (41.02%), Query Frame = 1
Query: 1096 TISEKKSIYKYNLKDLFPFTTYCIWMESENPLGVSPPTIALTVKTLPTSPQLSPRSITATSISNTAILVAWRPP--ERKFGKFKYYQIIYTNNDGFLPQHWRQFAVKDDNVMLTHLIASELYHIRVKIVNEIGHGPLSKTISIKTIAGTLSQCPDFKITEIFQSHIKLQWGTPDPVK---LFKLIQYNLLCWDV-----RLKIVNATAKSSTLFPILNHNLSMNEMEYVLYLKNEKEI----KCRLSAINSDGK---GMPTEIQASTVNKGVNYQNLIHIDKIGSTYITFQWRPP 1929
TI K + + L TY + ++N G + T P P+++ T ++ + + W PP + G Y ++Y + + Q Q D ++ L L Y I+V+ G GPLS +I +T+ +F++ ++ + L W PD K FK++ YN +V R I + + F ++N S +++++ ++ ++ SA DG+ MP ++Q ++ + Y ++ ID++G + +W P
Sbjct: 858 TIDFGKDDQHFTVTGLHKGATYVFRLAAKNRAGPGE-EFEKEITTPEDVPSGFPQNLRVTGLTTSTTELTWDPPVLAERNGHITNYTVVYRDINS---QLELQNVTNDTHLTLLGLKPDTTYDIKVRAHTSKGAGPLSPSIQSRTMPVEQVFAKNFRVAAAMKTSVLLSWEVPDSYKSAVPFKIL-YNGQSVEVDGHSMRKLIADLQPNTEYSFVLMNRGSSAGGLQHLVSIRTAPDLLPQKPLPASAFIEDGRFSLSMP-QVQDPSLVRWF-YIVVVPIDRVGGNLLAPRWNTP 1145
BLAST of Protein tyrosine phosphatase receptor type D vs. Ensembl Mouse
Match: Ptprs (protein tyrosine phosphatase, receptor type, S [Source:MGI Symbol;Acc:MGI:97815]) HSP 1 Score: 717.998 bits (1852), Expect = 0.000e+0 Identity = 334/612 (54.58%), Postives = 444/612 (72.55%), Query Frame = 1
Query: 3988 LSPVLVSDSIKLRIGSQKSENISDRPSISICNLYQYVTDLKANDCTLLQAEFETLNTNLDDRFTWQRSNIDSNKSKNRYANVVAYDHTSVLLTPVDDVIGSDYINANYIDGYQRQNAYIATQGPLPDTTDDFWRMVWEQRSNCIVMMTRLEERSGIKCHQYWPNRGFICYGQMIVSHIDTFVLAYYTIRLFEIRHSKYSEKREIQHFQFTAWPDHGVPKLSTPLLMFIRRVRSIGKIESCPKIVHCSAGVGRTGAFIVVDAQLERIKQEKNIDVFNYVSKIRCQRNYMVQTQAQYQFILETLLEAVEDGNTEVMACNFHAHVTKLSQIGISGSNQLSGFEMEFSKLNSLASNRGRHGVMLADFVKAAGNQAVNMTKNRVRNIIPYEWNRVVLNAIRGIEGSDYINASYIDGYRDRRAYIAAQSPIPSTVEDFWRMLWDQHCGVVIVLNQPHE---DKSHIYWPINKSIRYQFFVVDPVVEYNMPNYILREFKVTDARDGEFRALRQFQFTQWPNHGCPKESESILDFIRQVHKTKEQFGHMEPMVIHCNTGSGRTGVFIALSIVLDRLQQESVVDMYQTVKLLHKQRIGLVQTEEQYEFCYMAVLDYLSNYE 5814
L+P D +++R + ++ + P I I ++ +++ LKAND L E+E+++ +FTW+ SN+++NK KNRYANV+AYDH+ V+L P++ ++GSDYINANY+DGY+RQNAYIATQGPLP+T DFWRMVWEQRS +VMMTRLEE+S IKC QYWPNRG YG + V+ +DT LA + +R F + + SEKRE++HFQFTAWPDHGVP+ TP L F+RRV++ ++ P +VHCSAGVGRTG FIV+DA LERIK EK +DV+ +V+ +R QRNYMVQT+ QY FI E LLEAV GNTEV A + + ++ KL+Q + ++G E+EF +L S ++ R F+ A+ N KNR+ NI+PYE +RV L IRG+EGSDYINAS+IDGYR ++AYIA Q P+ T EDFWR LW+ + +V++L + E +K H YWP +S RYQ+FVVDP+ EYNMP YILREFKVTDARDG+ R +RQFQFT WP G PK E +DFI QVHKTKEQFG P+ +HC+ G GRTGVFI LSIVL+R++ E VVD++QTVK+L QR +VQTE++Y+FC+ A L+YL +++
Sbjct: 895 LAPHHPKDPVEMRRINFQTPGMLSHPPIPITDMAEHMERLKANDSLKLSQEYESIDPG--QQFTWEHSNLEANKPKNRYANVIAYDHSRVILQPLEGIMGSDYINANYVDGYRRQNAYIATQGPLPETFGDFWRMVWEQRSATVVMMTRLEEKSRIKCDQYWPNRGTETYGFIQVTLLDTMELATFCVRTFSLHKNGSSEKREVRHFQFTAWPDHGVPEYPTPFLAFLRRVKTCNPPDAGPIVVHCSAGVGRTGCFIVIDAMLERIKTEKTVDVYGHVTLMRSQRNYMVQTEDQYGFIHEALLEAVGCGNTEVPARSLYTYIQKLAQ--VEPGEHVTGMELEFKRLASSKAHTSR-------FITAS--LPCNKFKNRLVNILPYESSRVCLQPIRGVEGSDYINASFIDGYRQQKAYIATQGPLAETTEDFWRALWENNSTIVVMLTKLREMGREKCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDARDGQSRTVRQFQFTDWPEQGAPKSGEGFIDFIGQVHKTKEQFGQDGPISVHCSAGVGRTGVFITLSIVLERMRYEGVVDIFQTVKVLRTQRPAMVQTEDEYQFCFQAALEYLGSFD 1493 HSP 2 Score: 201.445 bits (511), Expect = 2.619e-51 Identity = 103/262 (39.31%), Postives = 149/262 (56.87%), Query Frame = 1
Query: 5092 NQAVNMTKNRVRNIIPYEWNRVVLNAIRGIEGSDYINASYIDGYRDRRAYIAAQSPIPSTVEDFWRMLWDQHCGVVIVLNQPHEDKSHI----YWPINKSIRYQFFVVDPVVEYNMPNYILREFKVTDARDGEFRALRQFQFTQWPNHGCPKESESILDFIRQVHKTKEQFGHMEPMVIHCNTGSGRTGVFIALSIVLDRLQQESVVDMYQTVKLLHKQRIGLVQTEEQYEFCYMAVLDYLSNYEKILEKSHLY*TYQDLSE 5865
N N KNR N+I Y+ +RV+L + GI GSDYINA+Y+DGYR + AYIA Q P+P T DFWRM+W+Q V+++ + E+KS I YWP + Y F V + + + +R F + E R +R FQFT WP+HG P+ L F+R+V P+V+HC+ G GRTG FI + +L+R++ E VD+Y V L+ QR +VQTE+QY F + A+L+ + + LY Q L++
Sbjct: 961 NLEANKPKNRYANVIAYDHSRVILQPLEGIMGSDYINANYVDGYRRQNAYIATQGPLPETFGDFWRMVWEQRSATVVMMTR-LEEKSRIKCDQYWPNRGTETYGFIQVTLLDTMELATFCVRTFSLHKNGSSEKREVRHFQFTAWPDHGVPEYPTPFLAFLRRVKTCNPP--DAGPIVVHCSAGVGRTGCFIVIDAMLERIKTEKTVDVYGHVTLMRSQRNYMVQTEDQYGFIHEALLEAVGCGNTEVPARSLYTYIQKLAQ 1219 HSP 3 Score: 131.724 bits (330), Expect = 6.740e-30 Identity = 129/567 (22.75%), Postives = 240/567 (42.33%), Query Frame = 1
Query: 268 VLINSQITFTENDEAP----KISLIIQSPNVLLFKSMILACSSTGHPVPSISWKINESPIEELKSPLKKLQNPPRIFSIKNYQNSVLVITQLIESDSNSVLICEAENNAGFDSRQQQLKVISTETDIP--SGFPVFQNNFFPIIKPYNSNVTLVCQAYGNPPPLIQWFKNYELINESFTKIKILNDGNLLLVQVTREDKGIYHCQAQNTNGLRLSDPSTLDITSYPISPNSLIIERFASDNVEISWRSGLNDVTEQENFILHYREVPENITEKQIMSKFVYLTISEKKSIYKYNLKDLFPFTTYCIWMESENPLGVSPPTIALTVKTLPTSPQLSPRSITATSISNTAILVAWRPPERKFGKFKYYQIIYTNNDGFLPQHWRQFAVKDDNVMLT--HLIASELYHIRVKIVNEIGHGPLSKTISIKTIAGTLSQCPDFKITEIFQSHIKLQWGTPDPVKLFKLIQYNLLCWDV-RLKIVNATAKSSTLFPILNHNLSMNEMEYVLYLKNEKEIKCRLSAINSDGKGMPTEIQASTVNKGVNYQNLIHIDKIGSTYITFQWRPPSKFS 1941
+ I++++T D+ P I + Q V ++ + C+++G+P P I+W + P++ S + IK ++ L I E+D C A N+AG + P S P+ I P NV + C A G+P P ++W + E T + G +L +D Y C A ++ G+ + + + + S P +P + ++ + ++ ++W SG D +++ Y+ ++ + I E + +Y++ L P + Y IW+ + N +G PP+ ++ +T +P +PR++ A +S T ++V W P G + Y++ YT +W++ V DD+++ T L+ E Y +RV +G GPLS I +KT G Q + + ++ I L W P + +I+Y LL + R + V T +T F + + LK E RL+A + G G T + + ++ +N + I T + W P ++
Sbjct: 116 ITIHAKLTVLREDQLPPGFPNIDMGPQLKVVERTRTATMLCAASGNPDPEITWFKDFLPVDPSASNGR----------IKQLRSGALQIESSEETDQGKYE-CVATNSAGVRYSSPANLYVRVRRVAPRFSILPMSHE-----IMP-GGNVNITCVAVGSPMPYVKWMQG----AEDLTPEDDMPVGRNVLELTDVKDSANYTCVAMSSLGV-IEAVAQITVKSLPKAPGTPVVTENTATSITVTWDSGNPDPVSY--YVIEYKSKSQDGPYQ----------IKEDITTTRYSIGGLSPNSEYEIWVSAVNSIGQGPPSESVVTRTGEQAPASAPRNVQARMLSATTMIVQWEEPVEPNGLIRGYRVYYTMEPEHPVGNWQKHNV-DDSLLTTVGSLLEDETYTVRVLAFTSVGDGPLSDPIQVKTQQGVPGQPMNLRAEAKSETSIGLSWSAP---RQESVIKYELLFREGDRGREVGRTFDPTTAFVVED-------------LKPNTEYAFRLAARSPQGLGAFTAVVRQRTLQAISPKNF-KVKMIMKTSVLLSWEFPDNYN 630 HSP 4 Score: 107.071 bits (266), Expect = 2.079e-22 Identity = 163/683 (23.87%), Postives = 268/683 (39.24%), Query Frame = 1
Query: 370 LACSSTGHPVPSISW-----KINESPIEELKSPLKKLQNPPRIFSIKNYQNSVLVITQLIESDSNSVLICEAENNAGFDSRQQQLKVISTETDIPSGFPVFQNNFFPIIKPYNSNVTLVCQAYGNPPPLIQWFKNYELINESFT--KIKILNDGNLLLVQVTREDKGIYHCQAQNTNGLRLSDPSTLDITSYPISPNSLII----ERFASDNVEIS------------WRSGLNDVTEQENFILHYREVPENITEKQIMSKFVYLTISEKKSIYKYNLKDLFPFTTYCIWMESENPLGVSPPTIALTVKTLPTSPQLSPRSITATSISNTAILVAWRPPERKFGKFKYYQIIYTNNDGFLPQHWRQFAVKDDNVMLTHLIAS----ELYHIRVKIVNEIGHGPLSKTISIKTIAGTLSQCP-DFKITEIFQSHIKLQWGTPDPVKLFKLIQYNLLCWDVRLKIVNATAKSSTLFPILN---HNLSMNEMEYVLYLKNEKEIKCRLSAINSDGKG-MPTEIQASTVNKGVNYQNL-IHIDKIGSTYITFQWRPPSKFSFDYFLWIYQIFDSEKLDRAVKLPKIKINISDSASAENGWFVYNYTNAFS-SSRYILGLRYLCRDSTDILREYVHRSDLVSTMKSVPSDSPKDLVVKEIDSNSALVSWKPLDQVHSNGIITHYEVRY 2316
C +TG P P ++W K+N E + +VL I L +V C A+N+ G + +L V+ E +P GFP + T++C A GNP P I WFK++ ++ S + +IK L G L + D+G Y C A N+ G+R S P+ L + ++P I+ E NV I+ W G D+T +++ V N+ E LT ++KD +T C+ M S LGV +TVK+LP +P + T + T+I V W YY I Y + P + +K+D + I Y I V VN IG GP S+++ +T + P + + + + + +QW +PV+ LI+ + + + + P+ N HN+ + + V L ++ R+ A S G G + IQ T +GV Q + + + T I W P + S + +++ D + P + D N AF ++R GL T ++R+ T++++ SPK+ VK I S L+SW+ D +S T Y+++Y
Sbjct: 52 FVCQATGDPKPRVTWNKKGKKVNSQRFETI--------------DFDESSGAVLRIQPLRTPRDENVYECVAQNSVGEITIHAKLTVLR-EDQLPPGFPNIDMGPQLKVVERTRTATMLCAASGNPDPEITWFKDFLPVDPSASNGRIKQLRSGALQIESSEETDQGKYECVATNSAGVRYSSPANLYVRVRRVAPRFSILPMSHEIMPGGNVNITCVAVGSPMPYVKWMQGAEDLTPEDDM-----PVGRNVLE---------LT----------DVKDSANYT--CVAMSS---LGVIEAVAQITVKSLPKAPG----TPVVTENTATSITVTWD--SGNPDPVSYYVIEYKSKSQDGP-----YQIKEDITTTRYSIGGLSPNSEYEIWVSAVNSIGQGPPSESVVTRTGEQAPASAPRNVQARMLSATTMIVQW--EEPVEPNGLIRGYRVYYTMEPE-----------HPVGNWQKHNVDDSLLTTVGSLLEDETYTVRVLAFTSVGDGPLSDPIQVKT-QQGVPGQPMNLRAEAKSETSIGLSWSAPRQESVIKYELLFREGDRGREVGRTFDPTTAFVVEDLKP--------NTEYAFRLAARSPQGLGAF----TAVVRQ--------RTLQAI---SPKNFKVKMIMKTSVLLSWEFPDNYNSP---TPYKIQY 639 HSP 5 Score: 63.5438 bits (153), Expect = 3.095e-9 Identity = 66/265 (24.91%), Postives = 125/265 (47.17%), Query Frame = 1
Query: 2164 SDLVSTMKSVPSDSPKDLVVKEIDSNSALVSWKPLDQVHSNGIITHYEVRYYAPKKEESTERF----INVSETSAILSNLKYFHYVIYVRAFTKVGGGSWSNPKNYYRQNLEEFP-IPTTIKGERKSETEINISWELPVLSEKNLAHAAIEGFIILYAPVESSPKWIKYTVQSKNLSAVIKGLEPDLRYQFQIAATNYAGFNGNFSEIVQEM------PKNFPNLNLKTVPDLRCSVQSSNRLKVEWSSPSISTDLLKFEIRYSG 2925
S + T + P+ +P+++ + + + + +V W+ + V NG+I Y V YY + E + ++ S + + S L+ Y + V AFT VG G S+P Q + P P ++ E KSET I +SW P ++ + +L+ + + + T + V++ L+P+ Y F++AA + G G F+ +V++ PKNF +K + ++ SV S ++SP+ ++I+Y+G
Sbjct: 403 SVVTRTGEQAPASAPRNVQARMLSATTMIVQWE--EPVEPNGLIRGYRV-YYTMEPEHPVGNWQKHNVDDSLLTTVGSLLEDETYTVRVLAFTSVGDGPLSDPIQVKTQ--QGVPGQPMNLRAEAKSETSIGLSWSAP-------RQESVIKYELLFREGDRG-REVGRTFDPTT-AFVVEDLKPNTEYAFRLAARSPQGL-GAFTAVVRQRTLQAISPKNF---KVKMI--MKTSVLLSWEFPDNYNSPT------PYKIQYNG 641
BLAST of Protein tyrosine phosphatase receptor type D vs. Ensembl Mouse
Match: Ptprd (protein tyrosine phosphatase, receptor type, D [Source:MGI Symbol;Acc:MGI:97812]) HSP 1 Score: 713.375 bits (1840), Expect = 0.000e+0 Identity = 333/606 (54.95%), Postives = 440/606 (72.61%), Query Frame = 1
Query: 4006 SDSIKLRIGSQKSENISDRPSISICNLYQYVTDLKANDCTLLQAEFETLNTNLDDRFTWQRSNIDSNKSKNRYANVVAYDHTSVLLTPVDDVIGSDYINANYIDGYQRQNAYIATQGPLPDTTDDFWRMVWEQRSNCIVMMTRLEERSGIKCHQYWPNRGFICYGQMIVSHIDTFVLAYYTIRLFEIRHSKYSEKREIQHFQFTAWPDHGVPKLSTPLLMFIRRVRSIGKIESCPKIVHCSAGVGRTGAFIVVDAQLERIKQEKNIDVFNYVSKIRCQRNYMVQTQAQYQFILETLLEAVEDGNTEVMACNFHAHVTKLSQIGISGSNQLSGFEMEFSKLNSLASNRGRHGVMLADFVKAAGNQAVNMTKNRVRNIIPYEWNRVVLNAIRGIEGSDYINASYIDGYRDRRAYIAAQSPIPSTVEDFWRMLWDQHCGVVIVLNQPHE---DKSHIYWPINKSIRYQFFVVDPVVEYNMPNYILREFKVTDARDGEFRALRQFQFTQWPNHGCPKESESILDFIRQVHKTKEQFGHMEPMVIHCNTGSGRTGVFIALSIVLDRLQQESVVDMYQTVKLLHKQRIGLVQTEEQYEFCYMAVLDYLSNYE 5814
+D ++LR + ++ ++ P I I L ++ LKAND E+E+++ +FTW+ SN++ NK KNRYANV+AYDH+ VLL+ ++ + GSDY+NANYIDGY++QNAYIATQG LP+T DFWRM+WEQRS +VMMT+LEERS +KC QYWP+RG +G + V+ +DT LA Y +R F + + SEKRE++ FQFTAWPDHGVP+ TP L F+RRV++ ++ P +VHCSAGVGRTG FIV+DA LERIK EK +D++ +V+ +R QRNYMVQT+ QY FI + LLEAV GNTEV A N +A++ KL+QI +G N ++G E+EF +L S ++ R F+ A N N KNR+ NI+PYE RV L IRG+EGSDYINAS++DGYR ++AYIA Q P+ T EDFWRMLW+ + +V++L + E +K H YWP +S RYQ+FVVDP+ EYNMP YILREFKVTDARDG+ R +RQFQFT WP G PK E +DFI QVHKTKEQFG P+ +HC+ G GRTGVFI LSIVL+R++ E VVD++QTVK+L QR +VQTE+QY+FCY A L+YL +++
Sbjct: 1316 TDPVELRRLNFQTPGMASHPPIPILELADHIERLKANDNLKFSQEYESIDPG--QQFTWEHSNLEVNKPKNRYANVIAYDHSRVLLSAIEGIPGSDYVNANYIDGYRKQNAYIATQGSLPETFGDFWRMIWEQRSATVVMMTKLEERSRVKCDQYWPSRGTETHGLVQVTLLDTVELATYCVRTFALYKNGSSEKREVRQFQFTAWPDHGVPEHPTPFLAFLRRVKTCNPPDAGPMVVHCSAGVGRTGCFIVIDAMLERIKHEKTVDIYGHVTLMRAQRNYMVQTEDQYIFIHDALLEAVTCGNTEVPARNLYAYIQKLTQIE-TGEN-VTGMELEFKRLASSKAHTSR-------FISA--NLPCNKFKNRLVNIMPYESTRVCLQPIRGVEGSDYINASFLDGYRQQKAYIATQGPLAETTEDFWRMLWEHNSTIVVMLTKLREMGREKCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDARDGQSRTVRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKEQFGQDGPISVHCSAGVGRTGVFITLSIVLERMRYEGVVDIFQTVKMLRTQRPAMVQTEDQYQFCYRAALEYLGSFD 1908 HSP 2 Score: 204.142 bits (518), Expect = 5.407e-52 Identity = 104/262 (39.69%), Postives = 153/262 (58.40%), Query Frame = 1
Query: 5092 NQAVNMTKNRVRNIIPYEWNRVVLNAIRGIEGSDYINASYIDGYRDRRAYIAAQSPIPSTVEDFWRMLWDQHCGVVIVLNQPHEDKSHI----YWPINKSIRYQFFVVDPVVEYNMPNYILREFKVTDARDGEFRALRQFQFTQWPNHGCPKESESILDFIRQVHKTKEQFGHMEPMVIHCNTGSGRTGVFIALSIVLDRLQQESVVDMYQTVKLLHKQRIGLVQTEEQYEFCYMAVLDYLSNYEKILEKSHLY*TYQDLSE 5865
N VN KNR N+I Y+ +RV+L+AI GI GSDY+NA+YIDGYR + AYIA Q +P T DFWRM+W+Q V+++ + E++S + YWP + + V + + Y +R F + E R +RQFQFT WP+HG P+ L F+R+V PMV+HC+ G GRTG FI + +L+R++ E VD+Y V L+ QR +VQTE+QY F + A+L+ ++ + +LY Q L++
Sbjct: 1376 NLEVNKPKNRYANVIAYDHSRVLLSAIEGIPGSDYVNANYIDGYRKQNAYIATQGSLPETFGDFWRMIWEQRSATVVMMTK-LEERSRVKCDQYWPSRGTETHGLVQVTLLDTVELATYCVRTFALYKNGSSEKREVRQFQFTAWPDHGVPEHPTPFLAFLRRVKTCNPP--DAGPMVVHCSAGVGRTGCFIVIDAMLERIKHEKTVDIYGHVTLMRAQRNYMVQTEDQYIFIHDALLEAVTCGNTEVPARNLYAYIQKLTQ 1634 HSP 3 Score: 138.272 bits (347), Expect = 7.020e-32 Identity = 208/853 (24.38%), Postives = 316/853 (37.05%), Query Frame = 1
Query: 376 CSSTGHPVPSISWKINESPIEELKSPLKKLQNPP-RIFSIKNYQNSVLVITQLIESDSNSVLICEAENNAGFDSRQQQLKVISTETDIPSGFPVFQNNFFPIIKPYNSNVTLVCQAYGNPPPLIQWFKNYELINESFT--KIKILND---------GNLLLVQVTREDKGIYHCQAQNTNGLRLSDPSTLDITS----------YPISPNSLIIERFASDNVE----------ISWRSGLNDVTEQENFILHYREVPENITEKQIMSKFVYLTISEKKSIYKYNLKDLFPFTTY-CIWMESENPLGVSPPTIALTVKTLPTSPQLSPRSITATSISNTAILVAWRP--PERKFGKFKYYQIIYTNNDGFLPQHWRQFAVKDDNVMLTHLIASEL-----YHIRVKIVNEIGHGPLSKTISIKTIAGTLSQCP-DFKITEIFQSHIKLQWGTPDPVKLFKLIQYNLLCWDVRLKIVNATAKSSTLFPILNHNLSMNEMEYVLYLKNEKEIKCRLSAINSDGKG-MPTEIQASTVNKGVNYQNL-IHIDKIGSTYITFQWRPPSKFSFDYFLWIYQIFDSEKLDRAVKLPKIKINISDSASAENGWFVYNYTNAFSSSRYILGLRYLCRDSTDILREYVHRSDLVSTMKSVPSDSPKDLVVKEIDSNSALVSWKPLDQVHSNGIITHYEVRYYAPKKEESTER---FINVSETSAILSNL-KYFHYVIYVRAFTKVGGGSWSNPKNYYRQNLEEFP--IPTTIKGERKSETEINISWELPVLSEKNLAHAAIEGFIILYAPVESSPKWIKYTVQSKNLS-------------AVIKGLEPDLRYQFQIAATNYAG 2748
C +TG P P I W KK+ N + + SVL I L ++ C A NN G S +L V+ E IP GFP + T++C A GNP P I WFK++ ++ S +IK L G L + Q D+G Y C A N+ G R S P+ L + + I P + I S N+ + W G D+T +++ + N+ E L D+ Y C+ M + LGV +TVK LP P + T + T+I + W PE YY I + P++ + + D + T + L Y RV VN IG GP S+ + +T S P D + + + I +QW P+ + N R+ + + + HN++ +++ + L +K ++ A S G G + ++IQ T GV Q L + T I W PP + + +Y+ D + R I I S Y +S Y R R + S TM+S PS P+D+ S S LVSW+P NGIIT Y ++Y A E+ I T +L L K+ Y I V A T VG G S + + E+ P P ++ E + T + +SW PV N H I G+ + Y +E+ + ++ L+ +I GL+P+ Y + A G
Sbjct: 45 CQATGDPRPKIVWNKKG----------KKVSNQRFEVIEFDDGSGSVLRIQPLRTPRDEAIYECVASNNVGEISVSTRLTVLR-EDQIPRGFPTIDMGPQLKVVERTRTATMLCAASGNPDPEITWFKDFLPVDTSNNNGRIKQLRSESIGGTPIRGALQIEQSEESDQGKYECVATNSAGTRYSAPANLYVRELREVRRVPPRFSIPPTNHEIMPGGSVNITCVAVGSPMPYVKWMLGAEDLTPEDDM-----PIGRNVLE----------------------LNDVRQSANYTCVAMST---LGVIEAIAQITVKALPKPPG----TPVVTESTATSITLTWDSGNPE----PVSYYIIQHK------PKNSEEPYKEIDGIATTRYSVAGLSPYSDYEFRVVAVNNIGRGPASEPVLTQTSEQAPSSAPRDVQARMLSSTTILVQWKEPE--------EPNGQIQGYRVYYTMDPTQHVNNW--MKHNVADSQITTIGNLVPQKTYSVKVLAFTSIGDGPLSSDIQVIT-QTGVPGQPLNFKAEPESETSILLSWTPPRSDTIASYELVYRDGDQGEEQR--------ITIEPGTS-------YRLQGLKPNSLYY--FRLSARSPQGLGASTAEIS--ARTMQSKPSAPPQDISCTSPSSTSILVSWQPPPVEKQNGIITEYSLKYAAVDGEDFKPHEILGIPSDTTKYLLEQLEKWTEYRITVTAHTDVGPGPES--LSVLIRTDEDVPSGPPRKVEVEAVNATAVKVSWRSPV---PNKQHGQIRGYQVHYVKMENGEPKGQPMLKDVMLADAQWEFDDTTEHDMIISGLQPETSYSLTVTAYTTKG 807 HSP 4 Score: 137.887 bits (346), Expect = 8.595e-32 Identity = 218/978 (22.29%), Postives = 404/978 (41.31%), Query Frame = 1
Query: 268 VLINSQITFTENDEAPK----ISLIIQSPNVLLFKSMILACSSTGHPVPSISWKINESPIEELK--SPLKKLQNPPRIFSIKNYQ-NSVLVITQLIESDSNSVLICEAENNAGFD-SRQQQLKV--ISTETDIPSGFPVFQNNFFPIIKPYNSNVTLVCQAYGNPPPLIQWFKNYELINESFTKIKILNDG-NLLLVQVTREDKGIYHCQAQNTNGLRLSDPSTLDITSYPISPNSLIIERFASDNVEISWRSGLNDVTEQENFILHYREVPENITEKQIMSKFVYLTISEKKSIYKYNLKDLFPFTTYCIWMESENPLGVSPPTIALTVKTLPTSPQLSPRSITATSISNTAILVAWRPPERKFGKFKYYQIIYTNNDGFLPQHWRQFAVKDDNV-MLTHLIASELYHIRVKIVNEIGHGPLSKTISIKTIAGTLSQCPDFKITEIFQSHIKLQWGTPDPVKLFKLIQYNLLCWDVRLKIVNATAKSSTLFPILNHNLSMNEMEYVLYLKNEKEIKCRLSAINSDGKGMPT-EIQASTV-NKGVNYQNLIHIDKIGSTYITFQWRPPSKFSFDYFLWIYQIFDSEKLDRAVKLPKIKINISDSASAENGWFVYNYTNAFSSSRYILGLRYLCRDSTDILREYVHRSDLVSTMKSVPSDSPKDLVVKEIDSNSALVSWKPLDQVHSNGIITHYEVRYYA-----PKKE---------ESTERFINVSETSAILSNLK-YFHYVIYVRAFTKVGGGSWSNPKNYYRQNLEEFPIPTTIKGERK---SETEIN---ISWELPVLSEKNLAHAAIEGFIILYAPVESSP-KWIKYTVQSKNLSAVIKGLEPDLRYQFQIAATNYAGFNGNFSE---IVQEMPKNFPNLNLKTVPDLRCSVQSSNRLKVEWSSPSISTDLLKFEIRYSGNLSYITEIGLKKSEFIDMESKSVNFETLVNRYD--VTLENLQSNALYKIAVRA 3078
+ +++++T D+ P+ I + Q V ++ + C+++G+P P I+W + P++ +K+L R SI L I Q ESD C A N+AG S L V + +P F + N I P S V + C A G+P P ++W L E T + G N+L + R+ Y C A +T G+ + + + + + P P + ++ + ++ ++W SG + +I+ ++ P+N E Y I + + +Y++ L P++ Y + + N +G P + + +T +P +PR + A +S+T ILV W+ PE G+ + Y++ YT + +W + V D + + +L+ + Y ++V IG GPLS I + T G Q +FK ++ I L W P + + Y L+ D + T+ P ++ L + + Y RLSA + G G T EI A T+ +K I ST I W+PP + + Y + + K +I SD+ ++ ++ R + TD+ S L+ T + VPS P+ + V+ +++ + VSW+ +G I Y+V Y PK + ++ F + +E I+S L+ Y + V A+T G G+ S PK + G+ + + T++N I W PV + ++G+ + + + P ++++ + + +A + Y F+++A N GF + + +E+P FP +L +S +++ W P ++ +G ++ T + + D+ + E L+ D +TL L+S+ Y + VRA
Sbjct: 107 ISVSTRLTVLREDQIPRGFPTIDMGPQLKVVERTRTATMLCAASGNPDPEITWFKDFLPVDTSNNNGRIKQL----RSESIGGTPIRGALQIEQSEESDQGKYE-CVATNSAGTRYSAPANLYVRELREVRRVPPRFSIPPTNHE--IMPGGS-VNITCVAVGSPMPYVKWM----LGAEDLTPEDDMPIGRNVLELNDVRQSAN-YTCVAMSTLGV-IEAIAQITVKALPKPPGTPVVTESTATSITLTWDSGNPEPVSY--YIIQHK--PKNSEEP-------YKEI-DGIATTRYSVAGLSPYSDYEFRVVAVNNIGRGPASEPVLTQTSEQAPSSAPRDVQARMLSSTTILVQWKEPEEPNGQIQGYRVYYTMDPTQHVNNWMKHNVADSQITTIGNLVPQKTYSVKVLAFTSIGDGPLSSDIQVITQTGVPGQPLNFKAEPESETSILLSWTPP---RSDTIASYELVYRDGD----QGEEQRITIEPGTSYRLQGLKPNSLYYF--------RLSARSPQGLGASTAEISARTMQSKPSAPPQDISCTSPSSTSILVSWQPPPVEKQNGIITEYSLKYAAVDGEDFKPHEILGIPSDTTK-----YLLEQLEKWTEYRITVTAH------TDVGPGPESLSVLIRTDEDVPSGPPRKVEVEAVNATAVKVSWRSPVPNKQHGQIRGYQVHYVKMENGEPKGQPMLKDVMLADAQWEFDDTTEHDMIISGLQPETSYSLTVTAYTTKGDGARSKPKLVSTTG--------AVPGKPRLVINHTQMNTALIQWHPPVDT-----FGPLQGYRLKFGRKDMEPLTTLEFSEKEDHFTAT--DIHKGASYVFRLSARNKVGFGEEMVKEISVPEEIPTGFPQ-------NLHSEGTTSTSVQLSWQPPVLA--------ERNGVITKYTLL------YRDINVPLLPMEHLIVPADTSMTLTGLKSDTTYDVKVRA 996
BLAST of Protein tyrosine phosphatase receptor type D vs. UniProt/SwissProt
Match: sp|B0V2N1|PTPRS_MOUSE (Receptor-type tyrosine-protein phosphatase S OS=Mus musculus OX=10090 GN=Ptprs PE=1 SV=1) HSP 1 Score: 720.694 bits (1859), Expect = 0.000e+0 Identity = 339/635 (53.39%), Postives = 452/635 (71.18%), Query Frame = 1
Query: 3928 KSIPDLVNADS---VQMCQDGTKLSPVLVSDSIKLRIGSQKSENISDRPSISICNLYQYVTDLKANDCTLLQAEFETLNTNLDDRFTWQRSNIDSNKSKNRYANVVAYDHTSVLLTPVDDVIGSDYINANYIDGYQRQNAYIATQGPLPDTTDDFWRMVWEQRSNCIVMMTRLEERSGIKCHQYWPNRGFICYGQMIVSHIDTFVLAYYTIRLFEIRHSKYSEKREIQHFQFTAWPDHGVPKLSTPLLMFIRRVRSIGKIESCPKIVHCSAGVGRTGAFIVVDAQLERIKQEKNIDVFNYVSKIRCQRNYMVQTQAQYQFILETLLEAVEDGNTEVMACNFHAHVTKLSQIGISGSNQLSGFEMEFSKLNSLASNRGRHGVMLADFVKAAGNQAVNMTKNRVRNIIPYEWNRVVLNAIRGIEGSDYINASYIDGYRDRRAYIAAQSPIPSTVEDFWRMLWDQHCGVVIVLNQPHE---DKSHIYWPINKSIRYQFFVVDPVVEYNMPNYILREFKVTDARDGEFRALRQFQFTQWPNHGCPKESESILDFIRQVHKTKEQFGHMEPMVIHCNTGSGRTGVFIALSIVLDRLQQESVVDMYQTVKLLHKQRIGLVQTEEQYEFCYMAVLDYLSNYE 5814
K+ PD DS + + L+P D +++R + ++ + P I I ++ +++ LKAND L E+E+++ +FTW+ SN+++NK KNRYANV+AYDH+ V+L P++ ++GSDYINANY+DGY+RQNAYIATQGPLP+T DFWRMVWEQRS +VMMTRLEE+S IKC QYWPNRG YG + V+ +DT LA + +R F + + SEKRE++HFQFTAWPDHGVP+ TP L F+RRV++ ++ P +VHCSAGVGRTG FIV+DA LERIK EK +DV+ +V+ +R QRNYMVQT+ QY FI E LLEAV GNTEV A + + ++ KL+Q + ++G E+EF +L S ++ R F+ A+ N KNR+ NI+PYE +RV L IRG+EGSDYINAS+IDGYR ++AYIA Q P+ T EDFWR LW+ + +V++L + E +K H YWP +S RYQ+FVVDP+ EYNMP YILREFKVTDARDG+ R +RQFQFT WP G PK E +DFI QVHKTKEQFG P+ +HC+ G GRTGVFI LSIVL+R++ E VVD++QTVK+L QR +VQTE++Y+FC+ A L+YL +++
Sbjct: 1282 KNKPDSKRKDSEPRTKCLLNNADLAPHHPKDPVEMRRINFQTPGMLSHPPIPITDMAEHMERLKANDSLKLSQEYESIDPG--QQFTWEHSNLEANKPKNRYANVIAYDHSRVILQPLEGIMGSDYINANYVDGYRRQNAYIATQGPLPETFGDFWRMVWEQRSATVVMMTRLEEKSRIKCDQYWPNRGTETYGFIQVTLLDTMELATFCVRTFSLHKNGSSEKREVRHFQFTAWPDHGVPEYPTPFLAFLRRVKTCNPPDAGPIVVHCSAGVGRTGCFIVIDAMLERIKTEKTVDVYGHVTLMRSQRNYMVQTEDQYGFIHEALLEAVGCGNTEVPARSLYTYIQKLAQ--VEPGEHVTGMELEFKRLASSKAHTSR-------FITAS--LPCNKFKNRLVNILPYESSRVCLQPIRGVEGSDYINASFIDGYRQQKAYIATQGPLAETTEDFWRALWENNSTIVVMLTKLREMGREKCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDARDGQSRTVRQFQFTDWPEQGAPKSGEGFIDFIGQVHKTKEQFGQDGPISVHCSAGVGRTGVFITLSIVLERMRYEGVVDIFQTVKVLRTQRPAMVQTEDEYQFCFQAALEYLGSFD 1903 HSP 2 Score: 201.83 bits (512), Expect = 1.980e-50 Identity = 103/262 (39.31%), Postives = 149/262 (56.87%), Query Frame = 1
Query: 5092 NQAVNMTKNRVRNIIPYEWNRVVLNAIRGIEGSDYINASYIDGYRDRRAYIAAQSPIPSTVEDFWRMLWDQHCGVVIVLNQPHEDKSHI----YWPINKSIRYQFFVVDPVVEYNMPNYILREFKVTDARDGEFRALRQFQFTQWPNHGCPKESESILDFIRQVHKTKEQFGHMEPMVIHCNTGSGRTGVFIALSIVLDRLQQESVVDMYQTVKLLHKQRIGLVQTEEQYEFCYMAVLDYLSNYEKILEKSHLY*TYQDLSE 5865
N N KNR N+I Y+ +RV+L + GI GSDYINA+Y+DGYR + AYIA Q P+P T DFWRM+W+Q V+++ + E+KS I YWP + Y F V + + + +R F + E R +R FQFT WP+HG P+ L F+R+V P+V+HC+ G GRTG FI + +L+R++ E VD+Y V L+ QR +VQTE+QY F + A+L+ + + LY Q L++
Sbjct: 1371 NLEANKPKNRYANVIAYDHSRVILQPLEGIMGSDYINANYVDGYRRQNAYIATQGPLPETFGDFWRMVWEQRSATVVMMTR-LEEKSRIKCDQYWPNRGTETYGFIQVTLLDTMELATFCVRTFSLHKNGSSEKREVRHFQFTAWPDHGVPEYPTPFLAFLRRVKTCNPP--DAGPIVVHCSAGVGRTGCFIVIDAMLERIKTEKTVDVYGHVTLMRSQRNYMVQTEDQYGFIHEALLEAVGCGNTEVPARSLYTYIQKLAQ 1629 HSP 3 Score: 153.295 bits (386), Expect = 1.325e-35 Identity = 202/837 (24.13%), Postives = 331/837 (39.55%), Query Frame = 1
Query: 370 LACSSTGHPVPSISW-----KINESPIEELKSPLKKLQNPPRIFSIKNYQNSVLVITQLIESDSNSVLICEAENNAGFDSRQQQLKVISTETDIPSGFPVFQNNFFPIIKPYNSNVTLVCQAYGNPPPLIQWFKNYELINESFT--KIKILNDGNLLLVQVTREDKGIYHCQAQNTNGLRLSDPSTLDITSYPISPNSLII----ERFASDNVEIS------------WRSGLNDVTEQENFILHYREVPENITEKQIMSKFVYLTISEKKSIYKYNLKDLFPFTTYCIWMESENPLGVSPPTIALTVKTLPTSPQLSPRSITATSISNTAILVAWRPPERKFGKFKYYQIIYTNNDGFLPQHWRQFAVKDDNVMLTHLIAS----ELYHIRVKIVNEIGHGPLSKTISIKTIAGTLSQCP-DFKITEIFQSHIKLQWGTPDPVKLFKLIQYNLLCWDVRLKIVNATAKSSTLFPILN---HNLSMNEMEYVLYLKNEKEIKCRLSAINSDGKG-MPTEIQASTVNKGVNYQNL-IHIDKIGSTYITFQWRPPSKFSFDYFLWIYQIFDSEKLDRAVKLPKIKINISDSASAENGWFVYNYTNAFS-SSRYILGLRYLCRDSTDILREYVHRSDLVSTMKSVPSDSPKDLVVKEIDSNSALVSWKPLDQVHSNGIITHYEVRYYAPKKEESTERFIN---VSETSAILSNL-KYFHYVIYVRAFTKVGGGSWSNPKNYYRQNLEEFP--IPTTIKGERKSETEINISWELPVLSEKNLAHAAIEGFIILYAPVESS----PKWIKYTVQSKNLSAVIKGLEPDLRYQFQIAATNYAG 2748
C +TG P P ++W K+N E + +VL I L +V C A+N+ G + +L V+ E +P GFP + T++C A GNP P I WFK++ ++ S + +IK L G L + D+G Y C A N+ G+R S P+ L + ++P I+ E NV I+ W G D+T +++ V N+ E LT ++KD +T C+ M S LGV +TVK+LP +P + T + T+I V W YY I Y + P + +K+D + I Y I V VN IG GP S+++ +T + P + + + + + +QW +PV+ LI+ + + + + P+ N HN+ + + V L ++ R+ A S G G + IQ T +GV Q + + + T I W P + S + +++ D + P + D N AF ++R GL T ++R+ T+++ PS P+D+ + S + LVSW+P NG + Y VRY E+ + +N + T +L L K+ Y + A+T+VG G S+P + E+ P P ++ E + T I + W P + H I G+ + Y +E + P IK + + VI L+P+ Y +AA G
Sbjct: 52 FVCQATGDPKPRVTWNKKGKKVNSQRFETI--------------DFDESSGAVLRIQPLRTPRDENVYECVAQNSVGEITIHAKLTVLR-EDQLPPGFPNIDMGPQLKVVERTRTATMLCAASGNPDPEITWFKDFLPVDPSASNGRIKQLRSGALQIESSEETDQGKYECVATNSAGVRYSSPANLYVRVRRVAPRFSILPMSHEIMPGGNVNITCVAVGSPMPYVKWMQGAEDLTPEDDM-----PVGRNVLE---------LT----------DVKDSANYT--CVAMSS---LGVIEAVAQITVKSLPKAPG----TPVVTENTATSITVTWD--SGNPDPVSYYVIEYKSKSQDGP-----YQIKEDITTTRYSIGGLSPNSEYEIWVSAVNSIGQGPPSESVVTRTGEQAPASAPRNVQARMLSATTMIVQWE--EPVEPNGLIRGYRVYYTMEPE-----------HPVGNWQKHNVDDSLLTTVGSLLEDETYTVRVLAFTSVGDGPLSDPIQVKT-QQGVPGQPMNLRAEAKSETSIGLSWSAPRQESVIKYELLFREGDRGREVGRTFDPTTAFVVED--------LKPNTEYAFRLAARSPQGLGAF----TAVVRQ--------RTLQAKPSAPPQDVKCTSLRSTAILVSWRPPPPETHNGALVGYSVRYRPLGSEDPDPKEVNNIPPTTTQILLEALEKWTEYRVTAVAYTEVGPGPESSP--VVVRTDEDVPSAPPRKVEAEALNATAIRVLWRSPTPGRQ---HGQIRGYQVHYVRMEGAEARGPPRIKDIMLADAQEMVITNLQPETAYSITVAAYTMKG 794 HSP 4 Score: 153.295 bits (386), Expect = 1.430e-35 Identity = 197/878 (22.44%), Postives = 359/878 (40.89%), Query Frame = 1
Query: 268 VLINSQITFTENDEAPK----ISLIIQSPNVLLFKSMILACSSTGHPVPSISWKINESPIEELKSPLKKLQNPPRIFSIKNYQNSVLVITQLIESDSNSVLICEAENNAGFDSRQQQLKVISTETDIPSGFPVFQNNFFPI---IKPYNSNVTLVCQAYGNPPPLIQWFKNYELINESFTKIKILNDGNLLLVQVTREDKGIYHCQAQNTNGLRLSDPSTLDITSYPISPNSLIIERFASDNVEISWRSGLNDVTEQENFILHYREVPENITEKQIMSKFVYLTISEKKSIYKYNLKDLFPFTTYCIWMESENPLGVSPPTIALTVKTLPTSPQLSPRSITATSISNTAILVAWRPPERKFGKFKYYQIIYTNNDGFLPQHWRQFAVKDDNVMLT--HLIASELYHIRVKIVNEIGHGPLSKTISIKTIAGTLSQCPDFKITEIFQSHIKLQWGTPDPVKLFKLIQYNLLCWDV-RLKIVNATAKSSTLFPILNHNLSMNEMEYVLYLKNEKEIKCRLSAINSDGKGMPTEI--QASTVNKGVNYQNLIHIDKIGSTYITFQWRPPSKFSFDYFLWIYQI----FDSEKLDRAVKLPKIKINISDSAS-----AENGWFVYNYTNAFSSSRYILGLRYLCRDSTDILREYVHRSDLVSTMKSVPSDSPKDLVVKEIDSNSALVSWKPLDQVHSNGIITHYEVRYYAPKKEES--TERFINVSETSA---ILSNLK-YFHYVIYVRAFTKVGGGSWSNPKNYYRQN-LEEFPIPTTIKGERKSETEINISWELPVLSEKNLAHAAIEGFIILYAPVESSPKWIKYTVQSKNLSAVI-KGLEPDLRYQFQIAATN---YAGFNGNFSEIVQEMPKNFPNL 2805
+ I++++T D+ P I + Q V ++ + C+++G+P P I+W + P++ S + IK ++ L I E+D C A N+AG + P + + P+ I P NV + C A G+P P ++W + E T + G +L +D Y C A ++ G+ + + + + S P +P + ++ + ++ ++W SG D +++ Y+ S+ I E + +Y++ L P + Y IW+ + N +G PP+ ++ +T +P +PR++ A +S T ++V W P G + Y++ YT +W++ V DD+++ T L+ E Y +RV +G GPLS I +KT G Q + + ++ I L W P + +I+Y LL + R + V T +T F + + LK E RL+A + G G T + Q + K + + ST I WRPP + + L Y + SE D PK NI + + A W Y T A + + G +S+ + +V T + VPS P+ + + +++ + V W+ +G I Y+V Y + E+ R ++ A +++NL+ Y I V A+T G G+ S PK + + P T+ ++ E + WE P + A + G+ + + +++P ++ + +A KG Y F++AA I ++ P+ FP +
Sbjct: 116 ITIHAKLTVLREDQLPPGFPNIDMGPQLKVVERTRTATMLCAASGNPDPEITWFKDFLPVDPSASNGR----------IKQLRSGALQIESSEETDQGK-YECVATNSAGVRYSSPANLYVRVRRVAP------RFSILPMSHEIMP-GGNVNITCVAVGSPMPYVKWMQG----AEDLTPEDDMPVGRNVLELTDVKDSANYTCVAMSSLGV-IEAVAQITVKSLPKAPGTPVVTENTATSITVTWDSGNPDPVSY--YVIEYKS----------KSQDGPYQIKEDITTTRYSIGGLSPNSEYEIWVSAVNSIGQGPPSESVVTRTGEQAPASAPRNVQARMLSATTMIVQWEEPVEPNGLIRGYRVYYTMEPEHPVGNWQKHNV-DDSLLTTVGSLLEDETYTVRVLAFTSVGDGPLSDPIQVKTQQGVPGQPMNLRAEAKSETSIGLSWSAP---RQESVIKYELLFREGDRGREVGRTFDPTTAFVVED-------------LKPNTEYAFRLAARSPQGLGAFTAVVRQRTLQAKPSAPPQDVKCTSLRSTAILVSWRPPPPETHNGALVGYSVRYRPLGSEDPD-----PKEVNNIPPTTTQILLEALEKWTEYRVT-AVAYTEVGPG-----PESSPV---------VVRTDEDVPSAPPRKVEAEALNATAIRVLWRSPTPGRQHGQIRGYQVHYVRMEGAEARGPPRIKDIMLADAQEMVITNLQPETAYSITVAAYTMKGDGARSKPKVVVTKGAVLGRP---TLSVQQTPEGSLLARWEPPA----DAAEDPVLGYRLQFGREDAAPATLELAAWERRFAAPAHKGAT----YVFRLAARGRAGLGEEAAAALSIPEDAPRGFPQI 910 HSP 5 Score: 68.9366 bits (167), Expect = 5.219e-10 Identity = 66/265 (24.91%), Postives = 119/265 (44.91%), Query Frame = 1
Query: 2164 SDLVSTMKSVPSDSPKDLVVKEIDSNSALVSWKPLDQVHSNGIITHYEVRYYAPKKEESTERF----INVSETSAILSNLKYFHYVIYVRAFTKVGGGSWSNPKNYYRQNLEEFP-IPTTIKGERKSETEINISWELPVLSEKNLAHAAIEGFIILYAPVESSPKWIKYTVQSKNLSAVIKGLEPDLRYQFQIAATNYAGFNGNFSEIV-----QEMPKNFPNLNLKTVPDLRCSVQSSNRLKVEWSSPSISTD---LLKFEIRY 2919
S + T + P+ +P+++ + + + + +V W+ + V NG+I Y V YY + E + ++ S + + S L+ Y + V AFT VG G S+P Q + P P ++ E KSET I +SW P ++ + +L+ + + + T + V++ L+P+ Y F++AA + G G F+ +V Q P P D++C+ S + V W P T L+ + +RY
Sbjct: 403 SVVTRTGEQAPASAPRNVQARMLSATTMIVQWE--EPVEPNGLIRGYRV-YYTMEPEHPVGNWQKHNVDDSLLTTVGSLLEDETYTVRVLAFTSVGDGPLSDPIQVKTQ--QGVPGQPMNLRAEAKSETSIGLSWSAP-------RQESVIKYELLFREGDRG-REVGRTFDPTT-AFVVEDLKPNTEYAFRLAARSPQGL-GAFTAVVRQRTLQAKPSAPPQ-------DVKCTSLRSTAILVSWRPPPPETHNGALVGYSVRY 645
BLAST of Protein tyrosine phosphatase receptor type D vs. UniProt/SwissProt
Match: sp|Q64605|PTPRS_RAT (Receptor-type tyrosine-protein phosphatase S OS=Rattus norvegicus OX=10116 GN=Ptprs PE=1 SV=2) HSP 1 Score: 719.924 bits (1857), Expect = 0.000e+0 Identity = 337/635 (53.07%), Postives = 452/635 (71.18%), Query Frame = 1
Query: 3928 KSIPDLVNADS---VQMCQDGTKLSPVLVSDSIKLRIGSQKSENISDRPSISICNLYQYVTDLKANDCTLLQAEFETLNTNLDDRFTWQRSNIDSNKSKNRYANVVAYDHTSVLLTPVDDVIGSDYINANYIDGYQRQNAYIATQGPLPDTTDDFWRMVWEQRSNCIVMMTRLEERSGIKCHQYWPNRGFICYGQMIVSHIDTFVLAYYTIRLFEIRHSKYSEKREIQHFQFTAWPDHGVPKLSTPLLMFIRRVRSIGKIESCPKIVHCSAGVGRTGAFIVVDAQLERIKQEKNIDVFNYVSKIRCQRNYMVQTQAQYQFILETLLEAVEDGNTEVMACNFHAHVTKLSQIGISGSNQLSGFEMEFSKLNSLASNRGRHGVMLADFVKAAGNQAVNMTKNRVRNIIPYEWNRVVLNAIRGIEGSDYINASYIDGYRDRRAYIAAQSPIPSTVEDFWRMLWDQHCGVVIVLNQPHE---DKSHIYWPINKSIRYQFFVVDPVVEYNMPNYILREFKVTDARDGEFRALRQFQFTQWPNHGCPKESESILDFIRQVHKTKEQFGHMEPMVIHCNTGSGRTGVFIALSIVLDRLQQESVVDMYQTVKLLHKQRIGLVQTEEQYEFCYMAVLDYLSNYE 5814
K+ PD DS + + L+P D +++R + ++ + P I I ++ +++ LKAND L E+E+++ +FTW+ SN+++NK KNRYANV+AYDH+ V+L P++ ++GSDYINANY+DGY+RQNAYIATQGPLP+T DFWRMVWEQRS +VMMTRLEE+S +KC QYWPNRG YG + V+ +DT LA + +R F + + SEKRE++HFQFTAWPDHGVP+ TP L F+RRV++ ++ P +VHCSAGVGRTG FIV+DA LERI+ EK +DV+ +V+ +R QRNYMVQT+ QY FI E LLEAV GNTEV A + + ++ KL+Q + ++G E+EF +L S ++ R F+ A+ N KNR+ NI+PYE +RV L IRG+EGSDYINAS+IDGYR ++AYIA Q P+ T EDFWR LW+ + +V++L + E +K H YWP +S RYQ+FVVDP+ EYNMP YILREFKVTDARDG+ R +RQFQFT WP G PK E +DFI QVHKTKEQFG P+ +HC+ G GRTGVFI LSIVL+R++ E VVD++QTVK+L QR +VQTE++Y+FC+ A L+YL +++
Sbjct: 1282 KNKPDSKRKDSEPRTKCLLNNADLAPHHPKDPVEMRRINFQTPGMLSHPPIPITDMAEHMERLKANDSLKLSQEYESIDPG--QQFTWEHSNLEANKPKNRYANVIAYDHSRVILQPLEGIMGSDYINANYVDGYRRQNAYIATQGPLPETFGDFWRMVWEQRSATVVMMTRLEEKSRVKCDQYWPNRGTETYGFIQVTLLDTMELATFCVRTFSLHKNGSSEKREVRHFQFTAWPDHGVPEYPTPFLAFLRRVKTCNPPDAGPVVVHCSAGVGRTGCFIVIDAMLERIRTEKTVDVYGHVTLMRSQRNYMVQTEDQYSFIHEALLEAVGCGNTEVPARSLYTYIQKLAQ--VEPGEHVTGMELEFKRLASSKAHTSR-------FITAS--LPCNKFKNRLVNILPYESSRVCLQPIRGVEGSDYINASFIDGYRQQKAYIATQGPLAETTEDFWRALWENNSTIVVMLTKLREMGREKCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDARDGQSRTVRQFQFTDWPEQGAPKSGEGFIDFIGQVHKTKEQFGQDGPISVHCSAGVGRTGVFITLSIVLERMRYEGVVDIFQTVKVLRTQRPAMVQTEDEYQFCFQAALEYLGSFD 1903 HSP 2 Score: 201.83 bits (512), Expect = 2.248e-50 Identity = 102/262 (38.93%), Postives = 149/262 (56.87%), Query Frame = 1
Query: 5092 NQAVNMTKNRVRNIIPYEWNRVVLNAIRGIEGSDYINASYIDGYRDRRAYIAAQSPIPSTVEDFWRMLWDQHCGVVIVLNQPHEDKSHI----YWPINKSIRYQFFVVDPVVEYNMPNYILREFKVTDARDGEFRALRQFQFTQWPNHGCPKESESILDFIRQVHKTKEQFGHMEPMVIHCNTGSGRTGVFIALSIVLDRLQQESVVDMYQTVKLLHKQRIGLVQTEEQYEFCYMAVLDYLSNYEKILEKSHLY*TYQDLSE 5865
N N KNR N+I Y+ +RV+L + GI GSDYINA+Y+DGYR + AYIA Q P+P T DFWRM+W+Q V+++ + E+KS + YWP + Y F V + + + +R F + E R +R FQFT WP+HG P+ L F+R+V P+V+HC+ G GRTG FI + +L+R++ E VD+Y V L+ QR +VQTE+QY F + A+L+ + + LY Q L++
Sbjct: 1371 NLEANKPKNRYANVIAYDHSRVILQPLEGIMGSDYINANYVDGYRRQNAYIATQGPLPETFGDFWRMVWEQRSATVVMMTR-LEEKSRVKCDQYWPNRGTETYGFIQVTLLDTMELATFCVRTFSLHKNGSSEKREVRHFQFTAWPDHGVPEYPTPFLAFLRRVKTCNPP--DAGPVVVHCSAGVGRTGCFIVIDAMLERIRTEKTVDVYGHVTLMRSQRNYMVQTEDQYSFIHEALLEAVGCGNTEVPARSLYTYIQKLAQ 1629 HSP 3 Score: 160.614 bits (405), Expect = 7.967e-38 Identity = 199/878 (22.67%), Postives = 362/878 (41.23%), Query Frame = 1
Query: 268 VLINSQITFTENDEAPK----ISLIIQSPNVLLFKSMILACSSTGHPVPSISWKINESPIEELKSPLKKLQNPPRIFSIKNYQNSVLVITQLIESDSNSVLICEAENNAGFDSRQQQLKVISTETDIPSGFPVFQNNFFPI---IKPYNSNVTLVCQAYGNPPPLIQWFKNYELINESFTKIKILNDGNLLLVQVTREDKGIYHCQAQNTNGLRLSDPSTLDITSYPISPNSLIIERFASDNVEISWRSGLNDVTEQENFILHYREVPENITEKQIMSKFVYLTISEKKSIYKYNLKDLFPFTTYCIWMESENPLGVSPPTIALTVKTLPTSPQLSPRSITATSISNTAILVAWRPPERKFGKFKYYQIIYTNNDGFLPQHWRQFAVKDDNVMLT--HLIASELYHIRVKIVNEIGHGPLSKTISIKTIAGTLSQCPDFKITEIFQSHIKLQWGTPDPVKLFKLIQYNLLCWDV-RLKIVNATAKSSTLFPILNHNLSMNEMEYVLYLKNEKEIKCRLSAINSDGKGMPTEI--QASTVNKGVNYQNLIHIDKIGSTYITFQWRPPSKFSFDYFLWIYQI----FDSEKLDRAVKLPKIKINISDSAS-----AENGWFVYNYTNAFSSSRYILGLRYLCRDSTDILREYVHRSDLVSTMKSVPSDSPKDLVVKEIDSNSALVSWKPLDQVHSNGIITHYEVRYYAPKKEES--TERFINVSETSA---ILSNLK-YFHYVIYVRAFTKVGGGSWSNPKNYYRQN-LEEFPIPTTIKGERKSETEINISWELPVLSEKNLAHAAIEGFIILYAPVESSPKWIKYTVQSKNLSAVI-KGLEPDLRYQFQIAATNYAGFNGNFS---EIVQEMPKNFPNL 2805
+ +++++T D+ P I + Q V ++ + C+++G+P P I+W + P++ S + IK ++ L I E+D C A N+AG + P + + P+ I P NV + C A G+P P ++W + E T + G +L +D Y C A ++ G+ + + + + S P +P + ++ + ++ ++W SG D +++ Y+ S+ I E + +Y++ L P + Y IW+ + N +G PP+ ++ +T +P +PR++ A +S T ++V W P G + Y++ YT +W++ V DD+++ T L+ E Y +RV +G GPLS I +KT G Q + + ++ I L W P + +I+Y LL + R + V T +T F + + LK E RL+A + G G T + Q + K + + ST I WRPP + + L Y + SE D PK NI + + A W Y T A + + G +S+ + +V T + VPS P+ + + +++ + V W+ +G I Y+V Y + E+ R ++ A +++NL+ Y I V A+T G G+ S PK + + P T+ ++ E + WE P + A + G+ + + +++P ++ + +A KG Y F++AA AG S I ++ P+ FP +
Sbjct: 116 ITVHAKLTVLREDQLPPGFPNIDMGPQLKVVERTRTATMLCAASGNPDPEITWFKDFLPVDPSASNGR----------IKQLRSGALQIESSEETDQGK-YECVATNSAGVRYSSPANLYVRVRRVAP------RFSILPMSHEIMP-GGNVNITCVAVGSPMPYVKWMQG----AEDLTPEDDMPVGRNVLELTDVKDSANYTCVAMSSLGV-IEAVAQITVKSLPKAPGTPVVTENTATSITVTWDSGNPDPVSY--YVIEYKS----------KSQDGPYQIKEDITTTRYSIGGLSPNSEYEIWVSAVNSIGQGPPSESVVTRTGEQAPASAPRNVQARMLSATTMIVQWEEPVEPNGLIRGYRVYYTMEPEHPVGNWQKHNV-DDSLLTTVGSLLEDETYTVRVLAFTSVGDGPLSDPIQVKTQQGVPGQPMNLRAEAKSETSIGLSWSAP---RQESVIKYELLFREGDRGREVGRTFDPTTAFVVED-------------LKPNTEYAFRLAARSPQGLGAFTAVVRQRTLQAKPSAPPQDVKCTSLRSTAILVSWRPPPPETHNGALVGYSVRYRPLGSEDPD-----PKEVNNIPPTTTQILLEALEKWTEYRVT-AVAYTEVGPG-----PESSPV---------VVRTDEDVPSAPPRKVEAEALNATAIRVLWRSPTPGRQHGQIRGYQVHYVRMEGAEARGPPRIKDIMLADAQEMVITNLQPETAYSITVAAYTMKGDGARSKPKVVVTKGAVLGRP---TLSVQQTPEGSLLARWEPPA----DAAEDPVLGYRLQFGREDAAPATLELAAWERRFAAPAHKGAT----YVFRLAARGRAGLGEEASAALSIPEDAPRGFPQI 910 HSP 4 Score: 153.68 bits (387), Expect = 1.038e-35 Identity = 202/837 (24.13%), Postives = 331/837 (39.55%), Query Frame = 1
Query: 370 LACSSTGHPVPSISW-----KINESPIEELKSPLKKLQNPPRIFSIKNYQNSVLVITQLIESDSNSVLICEAENNAGFDSRQQQLKVISTETDIPSGFPVFQNNFFPIIKPYNSNVTLVCQAYGNPPPLIQWFKNYELINESFT--KIKILNDGNLLLVQVTREDKGIYHCQAQNTNGLRLSDPSTLDITSYPISPNSLII----ERFASDNVEIS------------WRSGLNDVTEQENFILHYREVPENITEKQIMSKFVYLTISEKKSIYKYNLKDLFPFTTYCIWMESENPLGVSPPTIALTVKTLPTSPQLSPRSITATSISNTAILVAWRPPERKFGKFKYYQIIYTNNDGFLPQHWRQFAVKDDNVMLTHLIAS----ELYHIRVKIVNEIGHGPLSKTISIKTIAGTLSQCP-DFKITEIFQSHIKLQWGTPDPVKLFKLIQYNLLCWDVRLKIVNATAKSSTLFPILN---HNLSMNEMEYVLYLKNEKEIKCRLSAINSDGKG-MPTEIQASTVNKGVNYQNL-IHIDKIGSTYITFQWRPPSKFSFDYFLWIYQIFDSEKLDRAVKLPKIKINISDSASAENGWFVYNYTNAFS-SSRYILGLRYLCRDSTDILREYVHRSDLVSTMKSVPSDSPKDLVVKEIDSNSALVSWKPLDQVHSNGIITHYEVRYYAPKKEESTERFIN---VSETSAILSNL-KYFHYVIYVRAFTKVGGGSWSNPKNYYRQNLEEFP--IPTTIKGERKSETEINISWELPVLSEKNLAHAAIEGFIILYAPVESS----PKWIKYTVQSKNLSAVIKGLEPDLRYQFQIAATNYAG 2748
C +TG P P ++W K+N E + +VL I L +V C A+N+ G + +L V+ E +P GFP + T++C A GNP P I WFK++ ++ S + +IK L G L + D+G Y C A N+ G+R S P+ L + ++P I+ E NV I+ W G D+T +++ V N+ E LT ++KD +T C+ M S LGV +TVK+LP +P + T + T+I V W YY I Y + P + +K+D + I Y I V VN IG GP S+++ +T + P + + + + + +QW +PV+ LI+ + + + + P+ N HN+ + + V L ++ R+ A S G G + IQ T +GV Q + + + T I W P + S + +++ D + P + D N AF ++R GL T ++R+ T+++ PS P+D+ + S + LVSW+P NG + Y VRY E+ + +N + T +L L K+ Y + A+T+VG G S+P + E+ P P ++ E + T I + W P + H I G+ + Y +E + P IK + + VI L+P+ Y +AA G
Sbjct: 52 FVCQATGDPKPRVTWNKKGKKVNSQRFETI--------------DFDESSGAVLRIQPLRTPRDENVYECVAQNSVGEITVHAKLTVLR-EDQLPPGFPNIDMGPQLKVVERTRTATMLCAASGNPDPEITWFKDFLPVDPSASNGRIKQLRSGALQIESSEETDQGKYECVATNSAGVRYSSPANLYVRVRRVAPRFSILPMSHEIMPGGNVNITCVAVGSPMPYVKWMQGAEDLTPEDDM-----PVGRNVLE---------LT----------DVKDSANYT--CVAMSS---LGVIEAVAQITVKSLPKAPG----TPVVTENTATSITVTWD--SGNPDPVSYYVIEYKSKSQDGP-----YQIKEDITTTRYSIGGLSPNSEYEIWVSAVNSIGQGPPSESVVTRTGEQAPASAPRNVQARMLSATTMIVQWE--EPVEPNGLIRGYRVYYTMEPE-----------HPVGNWQKHNVDDSLLTTVGSLLEDETYTVRVLAFTSVGDGPLSDPIQVKT-QQGVPGQPMNLRAEAKSETSIGLSWSAPRQESVIKYELLFREGDRGREVGRTFDPTTAFVVED--------LKPNTEYAFRLAARSPQGLGAF----TAVVRQ--------RTLQAKPSAPPQDVKCTSLRSTAILVSWRPPPPETHNGALVGYSVRYRPLGSEDPDPKEVNNIPPTTTQILLEALEKWTEYRVTAVAYTEVGPGPESSP--VVVRTDEDVPSAPPRKVEAEALNATAIRVLWRSPTPGRQ---HGQIRGYQVHYVRMEGAEARGPPRIKDIMLADAQEMVITNLQPETAYSITVAAYTMKG 794 HSP 5 Score: 68.9366 bits (167), Expect = 5.677e-10 Identity = 66/265 (24.91%), Postives = 119/265 (44.91%), Query Frame = 1
Query: 2164 SDLVSTMKSVPSDSPKDLVVKEIDSNSALVSWKPLDQVHSNGIITHYEVRYYAPKKEESTERF----INVSETSAILSNLKYFHYVIYVRAFTKVGGGSWSNPKNYYRQNLEEFP-IPTTIKGERKSETEINISWELPVLSEKNLAHAAIEGFIILYAPVESSPKWIKYTVQSKNLSAVIKGLEPDLRYQFQIAATNYAGFNGNFSEIV-----QEMPKNFPNLNLKTVPDLRCSVQSSNRLKVEWSSPSISTD---LLKFEIRY 2919
S + T + P+ +P+++ + + + + +V W+ + V NG+I Y V YY + E + ++ S + + S L+ Y + V AFT VG G S+P Q + P P ++ E KSET I +SW P ++ + +L+ + + + T + V++ L+P+ Y F++AA + G G F+ +V Q P P D++C+ S + V W P T L+ + +RY
Sbjct: 403 SVVTRTGEQAPASAPRNVQARMLSATTMIVQWE--EPVEPNGLIRGYRV-YYTMEPEHPVGNWQKHNVDDSLLTTVGSLLEDETYTVRVLAFTSVGDGPLSDPIQVKTQ--QGVPGQPMNLRAEAKSETSIGLSWSAP-------RQESVIKYELLFREGDRG-REVGRTFDPTT-AFVVEDLKPNTEYAFRLAARSPQGL-GAFTAVVRQRTLQAKPSAPPQ-------DVKCTSLRSTAILVSWRPPPPETHNGALVGYSVRY 645
BLAST of Protein tyrosine phosphatase receptor type D vs. UniProt/SwissProt
Match: sp|A2A8L5|PTPRF_MOUSE (Receptor-type tyrosine-protein phosphatase F OS=Mus musculus OX=10090 GN=Ptprf PE=1 SV=1) HSP 1 Score: 718.383 bits (1853), Expect = 0.000e+0 Identity = 335/606 (55.28%), Postives = 434/606 (71.62%), Query Frame = 1
Query: 4006 SDSIKLRIGSQKSENISDRPSISICNLYQYVTDLKANDCTLLQAEFETLNTNLDDRFTWQRSNIDSNKSKNRYANVVAYDHTSVLLTPVDDVIGSDYINANYIDGYQRQNAYIATQGPLPDTTDDFWRMVWEQRSNCIVMMTRLEERSGIKCHQYWPNRGFICYGQMIVSHIDTFVLAYYTIRLFEIRHSKYSEKREIQHFQFTAWPDHGVPKLSTPLLMFIRRVRSIGKIESCPKIVHCSAGVGRTGAFIVVDAQLERIKQEKNIDVFNYVSKIRCQRNYMVQTQAQYQFILETLLEAVEDGNTEVMACNFHAHVTKLSQIGISGSNQLSGFEMEFSKLNSLASNRGRHGVMLADFVKAAGNQAVNMTKNRVRNIIPYEWNRVVLNAIRGIEGSDYINASYIDGYRDRRAYIAAQSPIPSTVEDFWRMLWDQHCGVVIVLNQPHE---DKSHIYWPINKSIRYQFFVVDPVVEYNMPNYILREFKVTDARDGEFRALRQFQFTQWPNHGCPKESESILDFIRQVHKTKEQFGHMEPMVIHCNTGSGRTGVFIALSIVLDRLQQESVVDMYQTVKLLHKQRIGLVQTEEQYEFCYMAVLDYLSNYE 5814
SD +++R + ++ + D P I I +L + LKAND E+E+++ +FTW+ SN + NK KNRYANV+AYDH+ VLLT +D V GSDYINANYIDGY++QNAYIATQGPLP+T DFWRMVWEQR+ +VMMTRLEE+S +KC QYWP RG YG + V+ +DT LA YT+R F + S SEKRE++ FQF AWPDHGVP+ TP+L F+RRV++ +++ P +VHCSAGVGRTG FIV+DA LER+K EK +D++ +V+ +R QRNYMVQT+ QY FI E LLEA G+TEV+A N +AH+ KL Q+ S ++ E+EF L + ++ R FV A N N KNR+ NI+PYE RV L IRG+EGSDYINAS++DGYR ++AYIA Q P+ + EDFWRMLW+ + ++++L + E +K H YWP +S RYQ+FVVDP+ EYNMP YILREFKVTDARDG+ R +RQFQFT WP G PK E +DFI QVHKTKEQFG P+ +HC+ G GRTGVFI LSIVL+R++ E VVDM+QTVK L QR +VQTE+QY+ CY A L+YL +++
Sbjct: 1302 SDPVEMRRLNYQTPGMRDHPPIPITDLADNIERLKANDGLKFSQEYESIDPG--QQFTWENSNSEVNKPKNRYANVIAYDHSRVLLTSIDGVPGSDYINANYIDGYRKQNAYIATQGPLPETMGDFWRMVWEQRTATVVMMTRLEEKSRVKCDQYWPVRGTETYGLIQVTLVDTVELATYTMRTFALHKSGSSEKRELRQFQFMAWPDHGVPEYPTPILAFLRRVKACNPLDAGPMVVHCSAGVGRTGCFIVIDAMLERMKHEKTVDIYGHVTCMRSQRNYMVQTEDQYVFIHEALLEAAMCGHTEVLARNLYAHIQKLGQVPPGES--VTAMELEFKLLANSKAHTSR-------FVSA--NLPCNKFKNRLVNIMPYELTRVCLQPIRGVEGSDYINASFLDGYRQQKAYIATQGPLAESTEDFWRMLWEHNSTIIVMLTKLREMGREKCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDARDGQSRTIRQFQFTDWPEQGVPKTGEGFIDFIGQVHKTKEQFGQDGPITVHCSAGVGRTGVFITLSIVLERMRYEGVVDMFQTVKTLRTQRPAMVQTEDQYQLCYRAALEYLGSFD 1894 HSP 2 Score: 161.384 bits (407), Expect = 4.910e-38 Identity = 226/964 (23.44%), Postives = 386/964 (40.04%), Query Frame = 1
Query: 277 NSQITFTENDEAPK----ISLIIQSPNVLLFKSMILACSSTGHPVPSISWKINESPIEELKSPLKKLQNPPRIFSIKNYQNSVLVITQLIESDSNSVLICEAENNAGFD-SRQQQLKVISTETDIPSGFPVFQNNFFPIIKPYNSNVTLVCQAYGNPPPLIQWFKNYELINESFTKIKILNDGN--LLLVQVTREDKGIYHCQAQNTNGLRLSDPSTLDITSYPISPNSLIIERFASDNVEISWRSGLNDVTEQENFI-LHYREVPENITEKQIMSKFVYLTISEKKSIYKYNLKDLFPFTTYCIWMESENPLGVSPPTIALTVKTLPTSPQLSPRSITATSISNTAILVAWRPPERKFGKFKYYQIIYTNNDGFLPQHWRQFAVKDDNVMLT---HLIASELYHIRVKIVNEIGHGPLSKTISIKTIAGTLSQCPDFKITEIFQSHIKLQWGTPDPVKLFKLIQYNLLCWDVRLKIVNATAKSSTLFPILNHNLSMNEMEYVLYLKNEKEIKCRLSAINSDGKGM--PT-EIQASTVNKGVNYQNLIHIDKIGSTYITFQWRPPSKFSFDYFLWIYQIFDSEKLDRAVKLPKIKINISDSASAENGWFVYNYTNAFSSSRYILGL------RYLCRDSTDILREYVHRSDLVSTMKSVPSDSPKDLVVKEIDSNSALVSWKPLDQVHSNGIITHYEVRYY-----APKKEESTERFINVSETSAILSNL-KYFHYVIYVRAFTKVGGGSWSNPKNYYRQNLEEFPIPTTIKGERKSETEINISWELPVLSEKNLAHAAIEGFIILYAPV-ESSPKWIKYTVQSKNLSAVIKGLEPDLRYQFQIAATNYAGFNGNFSEIV---QEMPKNFPNLNLKTVPDLRCSVQSSNRLKVEWSSPSISTDLLKFEIRYSGNLSYITEIGLKKSEFIDMESKSVNFETLVNRYDVTLENLQSNALYKIAVRA 3078
+++++ E D+ P I + Q V ++ + C++ G+P P ISW + P++ S + IK ++ L I ESD C A N+AG S L V P P +V L C A G P P ++W + E TK + G L L V R Y C A ++ G+ + + + + + P P L++ + +V ++W SG TE +F + YR + +++ + + +Y++ L PF+ Y + + N +G PP+ A+ +T +P PR + A +S + +LV W PPE G + Y++ YT + W + D +LT L+ Y +RV +G GP S TI +KT G +Q DF+ + I+L W P ++++Y L+ W + T P ++ L LK + +L+A + G G+ PT E + + Q + + GST + W PP S + + Y + AV K ++ D S E+ SS +LGL R R TD+ LV T + VPS P+ + V+ ++S + VSWK +G I Y+V Y P+ + + + +S L Y I V A+T G G+ S PK PT + T + + W P K L + G+ + Y E+ P I + ++ + + GL Y F++AA N AG F + + +++P FP +LR + +++ ++ W P ++ +G+++ T + + D+ S+ + + + N +TL L+ + Y I VRA
Sbjct: 119 SAKLSVLEEDQLPSGFPTIDMGPQLKVVEKGRTATMLCAAGGNPDPEISWFKDFLPVDPAASNGR----------IKQLRSGALQIESSEESDQGK-YECVATNSAGTRYSAPANLYVRVRRVAPRFSIPPSSQEVMP-----GGSVNLTCVAVGAPMPYVKWM----MGAEELTKEDEMPVGRNVLELSNVMRSAN--YTCVAISSLGM-IEATAQVTVKALPKPPIDLVVTETTATSVTLTWDSG---NTEPVSFYGIQYRAAGTDGPFQEV----------DGVASTRYSIGGLSPFSEYAFRVLAVNSIGRGPPSEAVRARTGEQAPSSPPRRVQARMLSASTMLVQWEPPEEPNGLVRGYRVYYTPDSRRPLSAWHKH--NTDAGLLTTVGSLLPGITYSLRVLAFTAVGDGPPSPTIQVKTQQGVPAQPADFQANAESDTRIQLSWLLP---PQERIVKYELVYWAAEDE---GQQHKVTFDPTSSYTLE--------DLKPDTLYHFQLAARSDLGVGVFTPTVEARTAQSTPSAPPQKVTCV-STGSTTVRVSWVPPPADSRNGIITQYSV-----AYEAVDGEDRKRHVVDGISREH------------SSWDLLGLEKWTEYRVWVRAHTDVGPGPESSPVLVRTDEDVPSGPPRKVEVEPLNSTAVHVSWKLPVPNKQHGQIRGYQVTYVRLENGEPRGQPIIQDVMLAEAQETTISGLTPETTYSITVAAYTTKGDGARSKPKVVTTTGAVPG-RPTMMVSTTAMHTAL-LQWHPP----KELP-GELLGYRLQYRRADEARPNTIDFGKDDQHFT--VTGLHKGATYVFRLAAKNRAGPGEEFEKEITTPEDVPSGFPQ-------NLRVTGLTTSTTELTWDPPVLA--------ERNGHITNYTVV------YRDINSQ-LELQNVTNDTHLTLLGLKPDTTYDIKVRA 981 HSP 3 Score: 157.147 bits (396), Expect = 8.441e-37 Identity = 243/1122 (21.66%), Postives = 413/1122 (36.81%), Query Frame = 1
Query: 235 NR*MFWIITQLVLINSQITFTENDEAPKISLIIQSPNVLLFKSMILACSSTGHPVPSISWKINESPIEELKSPLKKLQNPPRIFSIKNYQNSVLVITQLIESDSNSVLICEAENNAGFDSRQQQLKVISTETDIPSGFPVFQNNFFPIIKPYNSNVTLVCQAYGNPPPLIQWFKNYELINESFT--KIKILNDGNLLLVQVTREDKGIYHCQAQNTNGLRLSDPSTLDI------TSYPISPNSLIIERFASDNVE----------ISWRSGLNDVTEQENFILHYREVPENITE-KQIMSKFVYLTISEKKSIYKYNLKDLFPFTTYCIWMESENPLGVSPPTIALTVKTLPTSPQLSPRSITATSISNTAILVAWRPPERKFGKFKYYQIIYTNNDGFLPQHWRQFAVKDDNVMLTHLIASELYHIRVKIVNEIGHGPLSKTISIKTIAGTLSQCP-DFKITEIFQSHIKLQWGTPDPVKLFKLIQYNLLCWDVRLKIVNATAKSSTLFPILNHNLSMNEMEYVLYLKNEKEIKCRLSAINSDGKGMPTEIQASTVNKGVNYQNL-IHIDKIGSTYITFQW-RPPSKFSFDYFLWIYQIFDSEKLDRAVKLPKIKINISDSASAENGWFVYNYTNAFSSSRYILGLRYLCRDSTDILREYVHRSDLVSTMKSVPSDSPKDLVVKEIDSNSALVSWKPLDQVHSNGIITHYEVRYYAPKKEESTERFIN--VSETSA--ILSNLKYFHYVIYVRAFTKVGGGSWSNPKNYYRQNLEEFP--IPTTIKGERKSETEINISWELPVLSEKNLAHAAIEGFIILYAPVESSPKWIKYTVQSKNLS----AVIKGLEPDLRYQFQIAATNYAGFNGNFSEIVQEMPKNFPNLNLKTVPDLRCSVQSSNRLKVEWSSP-SISTDLLKFEIRYSGNLSYITEIGLKKSEFIDMESKSVNFETLVNRYDVTLENLQSNALYKIAVRAIYQNKELYESHRETTCDTMPAVPNLVKPPIIVGLDEEKSKVIIKLHRCSQRNGKISYYFVIVAAFQGNKNQQISFQEDTES--YTFMELSVNT------RSNNAKG----------EYIAIMKDINDIFKVSGKDHSSVLL 3447
R M ++ LV++ + D P + + L C +TG P P I+W +K K + + SVL I L ++ C A N+ G + +L V+ E +PSGFP + T++C A GNP P I WFK++ ++ + + +IK L G L + D+G Y C A N+ G R S P+ L + + I P+S + S N+ + W G ++T+++ V N+ E +M Y C+ + S LG+ T +TVK LP P + T + T++ + W + F Q DG + V + L Y RV VN IG GP S+ + +T S P + + S + +QW P+ + N L R+ + + + + HN + V L R+ A + G G P+ +GV Q + T I W PP + Y L + D + + P + D +Y++ A +R LG+ + V T +S PS P+ + S + VSW P NGIIT Y V Y A E+ ++ E S+ +L K+ Y ++VRA T VG G S+P + E+ P P ++ E + T +++SW+LPV N H I G+ + Y +E+ + +Q L+ I GL P+ Y +AA G V P P + S + + ++W P + +LL + ++Y ++++ + +++F + VT + + ++++A + E +E T D P ++ + GL +++ ++RNG I+ Y V+ + N Q+ Q T T + L +T R++ +KG + + + F+V+ +SVLL
Sbjct: 8 GRRMVPLVPALVMLG-LMAGAHGDSKPVFVKVPEDQTGLSGGVASFVCQATGEPKPRITW---------MKKGKKVSSQRFEVIEFDDGAGSVLRIQPLRVQRDEAIYECTATNSLGEINTSAKLSVLE-EDQLPSGFPTIDMGPQLKVVEKGRTATMLCAAGGNPDPEISWFKDFLPVDPAASNGRIKQLRSGALQIESSEESDQGKYECVATNSAGTRYSAPANLYVRVRRVAPRFSIPPSSQEVMPGGSVNLTCVAVGAPMPYVKWMMGAEELTKEDEM-----PVGRNVLELSNVMRSANYT----------------------CVAISS---LGMIEATAQVTVKALPKPPI----DLVVTETTATSVTLTWDSGNTEPVSFYGIQYRAAGTDGPFQE---VDGVASTRYSIGGLSPFSEYAFRVLAVNSIGRGPPSEAVRARTGEQAPSSPPRRVQARMLSASTMLVQWEPPE--------EPNGLVRGYRVYYTPDSRRPLSAW--HKHNTDAGLLTTVGSLLPGITYSLRVLAFTAVGDGPPSPTIQVKTQQGVPAQPADFQANAESDTRIQLSWLLPPQERIVKYELVYWAAEDEGQQHKVTFDPTSSYTLEDLKPDT----LYHFQLA---ARSDLGV--------GVFTPTVE----ARTAQSTPSAPPQKVTCVSTGSTTVRVSWVPPPADSRNGIITQYSVAYEAVDGEDRKRHVVDGISREHSSWDLLGLEKWTEYRVWVRAHTDVGPGPESSP--VLVRTDEDVPSGPPRKVEVEPLNSTAVHVSWKLPV---PNKQHGQIRGYQVTYVRLENGEPRGQPIIQDVMLAEAQETTISGLTPETTYSITVAAYTTKGDGARSKPKVVTTTGAVPGR-----PTMMVSTTAMHTALLQWHPPKELPGELLGYRLQY------------RRAD--EARPNTIDFGKDDQHFTVTGLHKGATYVFRLAAKNRAGPGEEFEKEITTPEDVPSGFPQNLR---VTGLTTSTTELTWDPPVLAERNGHITNYTVVYR----DINSQLELQNVTNDTHLTLLGLKPDTTYDIKVRAHTSKGAGPLSPSIQSRTMPVEQVFAKNFRVAAAMKTSVLL 1021
BLAST of Protein tyrosine phosphatase receptor type D vs. UniProt/SwissProt
Match: sp|Q13332|PTPRS_HUMAN (Receptor-type tyrosine-protein phosphatase S OS=Homo sapiens OX=9606 GN=PTPRS PE=1 SV=3) HSP 1 Score: 717.227 bits (1850), Expect = 0.000e+0 Identity = 333/593 (56.16%), Postives = 432/593 (72.85%), Query Frame = 1
Query: 4045 ENISDRPSISICNLYQYVTDLKANDCTLLQAEFETLNTNLDDRFTWQRSNIDSNKSKNRYANVVAYDHTSVLLTPVDDVIGSDYINANYIDGYQRQNAYIATQGPLPDTTDDFWRMVWEQRSNCIVMMTRLEERSGIKCHQYWPNRGFICYGQMIVSHIDTFVLAYYTIRLFEIRHSKYSEKREIQHFQFTAWPDHGVPKLSTPLLMFIRRVRSIGKIESCPKIVHCSAGVGRTGAFIVVDAQLERIKQEKNIDVFNYVSKIRCQRNYMVQTQAQYQFILETLLEAVEDGNTEVMACNFHAHVTKLSQIGISGSNQLSGFEMEFSKLNSLASNRGRHGVMLADFVKAAGNQAVNMTKNRVRNIIPYEWNRVVLNAIRGIEGSDYINASYIDGYRDRRAYIAAQSPIPSTVEDFWRMLWDQHCGVVIVLNQPHE---DKSHIYWPINKSIRYQFFVVDPVVEYNMPNYILREFKVTDARDGEFRALRQFQFTQWPNHGCPKESESILDFIRQVHKTKEQFGHMEPMVIHCNTGSGRTGVFIALSIVLDRLQQESVVDMYQTVKLLHKQRIGLVQTEEQYEFCYMAVLDYLSNYE 5814
E++ P I I ++ ++ LKAND L E+E+++ +FTW+ SN++ NK KNRYANV+AYDH+ V+L P++ ++GSDYINANY+DGY+ QNAYIATQGPLP+T DFWRMVWEQRS IVMMTRLEE+S IKC QYWPNRG YG + V+ +DT LA + +R F + + SEKRE++ FQFTAWPDHGVP+ TP L F+RRV++ ++ P +VHCSAGVGRTG FIV+DA LERIK EK +DV+ +V+ +R QRNYMVQT+ QY FI E LLEAV GNTEV A + +A++ KL+Q + ++G E+EF +L + ++ R F+ A N N KNR+ NI+PYE RV L IRG+EGSDYINAS+IDGYR ++AYIA Q P+ T EDFWRMLW+ + +V++L + E +K H YWP +S RYQ+FVVDP+ EYNMP YILREFKVTDARDG+ R +RQFQFT WP G PK E +DFI QVHKTKEQFG P+ +HC+ G GRTGVFI LSIVL+R++ E VVD++QTVK+L QR +VQTE++Y+FCY A L+YL +++
Sbjct: 1365 ESMLSHPPIPIADMAEHTERLKANDSLKLSQEYESIDPG--QQFTWEHSNLEVNKPKNRYANVIAYDHSRVILQPIEGIMGSDYINANYVDGYRCQNAYIATQGPLPETFGDFWRMVWEQRSATIVMMTRLEEKSRIKCDQYWPNRGTETYGFIQVTLLDTIELATFCVRTFSLHKNGSSEKREVRQFQFTAWPDHGVPEYPTPFLAFLRRVKTCNPPDAGPIVVHCSAGVGRTGCFIVIDAMLERIKPEKTVDVYGHVTLMRSQRNYMVQTEDQYSFIHEALLEAVGCGNTEVPARSLYAYIQKLAQ--VEPGEHVTGMELEFKRLANSKAHTSR-------FISA--NLPCNKFKNRLVNIMPYESTRVCLQPIRGVEGSDYINASFIDGYRQQKAYIATQGPLAETTEDFWRMLWENNSTIVVMLTKLREMGREKCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDARDGQSRTVRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKEQFGQDGPISVHCSAGVGRTGVFITLSIVLERMRYEGVVDIFQTVKMLRTQRPAMVQTEDEYQFCYQAALEYLGSFD 1944 HSP 2 Score: 204.912 bits (520), Expect = 2.337e-51 Identity = 105/262 (40.08%), Postives = 151/262 (57.63%), Query Frame = 1
Query: 5092 NQAVNMTKNRVRNIIPYEWNRVVLNAIRGIEGSDYINASYIDGYRDRRAYIAAQSPIPSTVEDFWRMLWDQHCGVVIVLNQPHEDKSHI----YWPINKSIRYQFFVVDPVVEYNMPNYILREFKVTDARDGEFRALRQFQFTQWPNHGCPKESESILDFIRQVHKTKEQFGHMEPMVIHCNTGSGRTGVFIALSIVLDRLQQESVVDMYQTVKLLHKQRIGLVQTEEQYEFCYMAVLDYLSNYEKILEKSHLY*TYQDLSE 5865
N VN KNR N+I Y+ +RV+L I GI GSDYINA+Y+DGYR + AYIA Q P+P T DFWRM+W+Q ++++ + E+KS I YWP + Y F V + + + +R F + E R +RQFQFT WP+HG P+ L F+R+V P+V+HC+ G GRTG FI + +L+R++ E VD+Y V L+ QR +VQTE+QY F + A+L+ + + LY Q L++
Sbjct: 1412 NLEVNKPKNRYANVIAYDHSRVILQPIEGIMGSDYINANYVDGYRCQNAYIATQGPLPETFGDFWRMVWEQRSATIVMMTR-LEEKSRIKCDQYWPNRGTETYGFIQVTLLDTIELATFCVRTFSLHKNGSSEKREVRQFQFTAWPDHGVPEYPTPFLAFLRRVKTCNPP--DAGPIVVHCSAGVGRTGCFIVIDAMLERIKPEKTVDVYGHVTLMRSQRNYMVQTEDQYSFIHEALLEAVGCGNTEVPARSLYAYIQKLAQ 1670 HSP 3 Score: 147.132 bits (370), Expect = 1.134e-33 Identity = 210/979 (21.45%), Postives = 393/979 (40.14%), Query Frame = 1
Query: 268 VLINSQITFTENDEAPK----ISLIIQSPNVLLFKSMILACSSTGHPVPSISWKINESPIEELKSPLKKLQNPPRIFSIKNYQNSVLVITQLIESDSNSVLICEAENNAGFDSRQQQLKVISTETDIPSGFPVFQNNFFPI---IKPYNSNVTLVCQAYGNPPPLIQWFKNYELINESFTKIKILNDGNLLLVQVTREDKGIYHCQAQNTNGLRLSDPSTLDITSYPISPNSLIIERFASDNVEISWRSGLNDVTEQENFILHYREVPENITEKQIMSKFVYLTISEKKSIYKYNLKDLFPFTTYCIWMESENPLGVSPPTIALTVKTLPTSPQLSPRSITATSISNTAILVAWRPPERKFGKFKYYQIIYTNNDGFLPQHWRQFAVKDDNVMLT--HLIASELYHIRVKIVNEIGHGPLSKTISIKTIAGTLSQCPDFKITEIFQSHIKLQWGTPDPVKLFKLIQYNLLCWDV-RLKIVNATAKSSTLFPILNHNLSMNEMEYVLYLKNEKEIKCRLSAINSDGKGMPTEI--QASTVNKGVNYQNLIHIDKIGSTYITFQWRPPSKFSFDYFLWIYQIFDSEKLDRAVKLPKIKINISDSAS-----AENGWFVYNYTNAFSSSRYILGLRYLCRDSTDILREYVHRSDLVSTMKSVPSDSPKDLVVKEIDSNSALVSWKPLDQVHSNGIITHYEVRYYAPKKEES--TERFINV------------SETSAILSNLK-YFHYVIYVRAFTKVGGGSWSNPKNYYRQN-LEEFPIPTTIKGERKSETEINISWELPVLSEKNLAHAAIEGFIILYAPVESSP-KWIKYTVQSKNLSAVIKGLEPDLRYQFQIAATNYAGFNGNFSEIV---QEMPKNFPNLNLKTVPDLRCSVQSSNRLKVEWSSPSIS---TDLLKF--EIRYSGNLSYITEIGLKKSEFIDMESKSVNFETLVNRYDVTLENLQSNALYKIAVRA 3078
+ +++++T D+ P I + Q V ++ + C+++G+P P I+W + P++ S + Q F + + L I E+D C A N+AG + ++ P F + P+ I P NV + C A G+P P ++W + E T + G +L +D Y C A ++ G+ + + + + S P +P + ++ + ++ I+W SG D +++ Y+ S+ I E + +Y++ L P + Y IW+ + N +G PP+ ++ +T +P +PR++ A +S T ++V W P G + Y++ YT +W++ V DD+++ T L+ E Y +RV +G GPLS I +KT G Q + + ++ I L W P + +I+Y LL + + V T +T + + + LK E RL+A + G G T + Q + +K + + ST I WRPP + + L Y + L PK I + + A W Y T T++ +V T + VPS P+ + + +++ + V W+ +G I Y+V Y + E+ R +V +E +++NL+ Y I V A+T G G+ S PK + + P T+ ++ E + WE P A + G+ + + +S+P +++ +A G+ Y F++AA + G +E++ ++ P+ P + L+ + S+ + + W P + ++K+ +R +G L E L + E+ +TL+ L+ + Y + VRA
Sbjct: 116 ITVHAKLTVLREDQLPSGFPNIDMGPQLKVVERTRTATMLCAASGNPDPEITWFKDFLPVDPSASNGRIKQLRSETFESTPIRGA-LQIESSEETDQGKYE-CVATNSAGVRYSSPANLYVRELREVRRVAPRF--SILPMSHEIMP-GGNVNITCVAVGSPMPYVKWMQG----AEDLTPEDDMPVGRNVLELTDVKDSANYTCVAMSSLGV-IEAVAQITVKSLPKAPGTPMVTENTATSITITWDSGNPDPVSY--YVIEYKS----------KSQDGPYQIKEDITTTRYSIGGLSPNSEYEIWVSAVNSIGQGPPSESVVTRTGEQAPASAPRNVQARMLSATTMIVQWEEPVEPNGLIRGYRVYYTMEPEHPVGNWQKHNV-DDSLLTTVGSLLEDETYTVRVLAFTSVGDGPLSDPIQVKTQQGVPGQPMNLRAEARSETSITLSWSPP---RQESIIKYELLFREGDHGREVGRTFDPTTSYVVED-------------LKPNTEYAFRLAARSPQGLGAFTPVVRQRTLQSKPSAPPQDVKCVSVRSTAILVSWRPPPPETHNGALVGYSV-RYRPLGSEDPEPKEVNGIPPTTTQILLEALEKWTQYRITTV---------------AHTEVGPGPESSPVVVRTDEDVPSAPPRKVEAEALNATAIRVLWRSPAPGRQHGQIRGYQVHYVRMEGAEARGPPRIKDVMLADAQWETDDTAEYEMVITNLQPETAYSITVAAYTMKGDGARSKPKVVVTKGAVLGRP---TLSVQQTPEGSLLARWEPPA----GTAEDQVLGYRLQFGREDSTPLATLEFPPSEDRYTA--SGVHKGATYVFRLAARSRGGLGEEAAEVLSIPEDTPRGHPQI-LEAAGN-----ASAGTVLLRWLPPVPAERNGAIVKYTVAVREAGALGPARETELPAAAEPGAENA------------LTLQGLKPDTAYDLQVRA 1012 HSP 4 Score: 142.124 bits (357), Expect = 3.198e-32 Identity = 224/973 (23.02%), Postives = 376/973 (38.64%), Query Frame = 1
Query: 370 LACSSTGHPVPSISW-----KINESPIEELKSPLKKLQNPPRIFSIKNYQNSVLVITQLIESDSNSVLICEAENNAGFDSRQQQLKVISTETDIPSGFPVFQNNFFPIIKPYNSNVTLVCQAYGNPPPLIQWFKNYELINESFT--KIKILND---------GNLLLVQVTREDKGIYHCQAQNTNGLRLSDPSTLDITSY----PISPNSLII----ERFASDNVEIS------------WRSGLNDVTEQENFILHYREVPENITEKQIMSKFVYLTISEKKSIYKYNLKDLFPFTTYCIWMESENPLGVSPPTIALTVKTLPTSPQLSPRSITATSISNTAILVAWRPPERKFGKFKYYQIIYTNNDGFLPQHWRQFAVKDDNVMLTHLIAS----ELYHIRVKIVNEIGHGPLSKTISIKTIAGTLSQCP-DFKITEIFQSHIKLQWGTPDPVKLFKLIQYNLLCWDVRLKIVNATAKSSTLFPILN---HNLSMNEMEYVLYLKNEKEIKCRLSAINSDGKG-MPTEIQASTVNKGVNYQNL-IHIDKIGSTYITFQWRPPSKFSFDYFLWIYQIFDSEKLDRAVKLPKIKINISDSASAENGWFVYNYTNAFS-SSRYILGLRYLCRDSTDILREYVHRSDLVSTMKSVPSDSPKDLVVKEIDSNSALVSWKPLDQVHSNGIITHYEVRYYAPKKEESTERFIN---VSETSAILSNL-KYFHYVIYVRAFTKVGGGSWSNPKNYYRQNLEEFP--IPTTIKGERKSETEINISWELPVLSEKNLAHAAIEGFIILYAPVESS----PKWIK---------YTVQSKNLSAVIKGLEPDLRYQFQIAATNYAGFNGNFSE----IVQEMPKNFPNLNLKTVPDLRCSVQSSNRLKVEWSSPSISTDLLKFEIRYSGNLSYITEIGLKKSEFIDMESKSVNFETLVNRYDVTLENLQSNALYKIAVRA 3078
C +TG P P ++W K+N E ++ +VL I L +V C A+N+ G + +L V+ E +PSGFP + T++C A GNP P I WFK++ ++ S + +IK L G L + D+G Y C A N+ G+R S P+ L + ++P I+ E NV I+ W G D+T +++ V N+ E LT ++KD +T C+ M S LGV +TVK+LP +P + T + T+I + W YY I Y + P + +K+D + I Y I V VN IG GP S+++ +T + P + + + + + +QW +PV+ LI+ + + + + P+ N HN+ + + V L ++ R+ A S G G + IQ T +GV Q + + + T IT W PP + S + +++ D + P + D N AF ++R GL T ++R+ T++S PS P+D+ + S + LVSW+P NG + Y VRY E+ + +N + T +L L K+ Y I A T+VG G S+P + E+ P P ++ E + T I + W P + H I G+ + Y +E + P IK T + VI L+P+ Y +AA G +G S+ + + P L+++ P+ L W P+ + + L Y + G + S + ++ F +RY + + + ++++A R+
Sbjct: 52 FVCQATGDPKPRVTWNKKGKKVNSQRFETIE--------------FDESAGAVLRIQPLRTPRDENVYECVAQNSVGEITVHAKLTVLR-EDQLPSGFPNIDMGPQLKVVERTRTATMLCAASGNPDPEITWFKDFLPVDPSASNGRIKQLRSETFESTPIRGALQIESSEETDQGKYECVATNSAGVRYSSPANLYVRELREVRRVAPRFSILPMSHEIMPGGNVNITCVAVGSPMPYVKWMQGAEDLTPEDDM-----PVGRNVLE---------LT----------DVKDSANYT--CVAMSS---LGVIEAVAQITVKSLPKAPG----TPMVTENTATSITITWD--SGNPDPVSYYVIEYKSKSQDGP-----YQIKEDITTTRYSIGGLSPNSEYEIWVSAVNSIGQGPPSESVVTRTGEQAPASAPRNVQARMLSATTMIVQWE--EPVEPNGLIRGYRVYYTMEPE-----------HPVGNWQKHNVDDSLLTTVGSLLEDETYTVRVLAFTSVGDGPLSDPIQVKT-QQGVPGQPMNLRAEARSETSITLSWSPPRQESIIKYELLFREGDHGREVGRTFDPTTSYVVED--------LKPNTEYAFRLAARSPQGLGAF----TPVVRQ--------RTLQSKPSAPPQDVKCVSVRSTAILVSWRPPPPETHNGALVGYSVRYRPLGSEDPEPKEVNGIPPTTTQILLEALEKWTQYRITTVAHTEVGPGPESSP--VVVRTDEDVPSAPPRKVEAEALNATAIRVLWRSPAPGRQ---HGQIRGYQVHYVRMEGAEARGPPRIKDVMLADAQWETDDTAEYEMVITNLQPETAYSITVAAYTMKG-DGARSKPKVVVTKGAVLGRPTLSVQQTPE--------GSLLARWEPPAGTAE--------DQVLGYRLQFGREDSTPL----ATLEFPPSEDRYTASGVHKGATYVFRLAARS 909
BLAST of Protein tyrosine phosphatase receptor type D vs. UniProt/SwissProt
Match: sp|Q64604|PTPRF_RAT (Receptor-type tyrosine-protein phosphatase F OS=Rattus norvegicus OX=10116 GN=Ptprf PE=2 SV=1) HSP 1 Score: 717.227 bits (1850), Expect = 0.000e+0 Identity = 337/606 (55.61%), Postives = 436/606 (71.95%), Query Frame = 1
Query: 4006 SDSIKLRIGSQKSENISDRPSISICNLYQYVTDLKANDCTLLQAEFETLNTNLDDRFTWQRSNIDSNKSKNRYANVVAYDHTSVLLTPVDDVIGSDYINANYIDGYQRQNAYIATQGPLPDTTDDFWRMVWEQRSNCIVMMTRLEERSGIKCHQYWPNRGFICYGQMIVSHIDTFVLAYYTIRLFEIRHSKYSEKREIQHFQFTAWPDHGVPKLSTPLLMFIRRVRSIGKIESCPKIVHCSAGVGRTGAFIVVDAQLERIKQEKNIDVFNYVSKIRCQRNYMVQTQAQYQFILETLLEAVEDGNTEVMACNFHAHVTKLSQIGISGSNQLSGFEMEFSKLNSLASNRGRHGVMLADFVKAAGNQAVNMTKNRVRNIIPYEWNRVVLNAIRGIEGSDYINASYIDGYRDRRAYIAAQSPIPSTVEDFWRMLWDQHCGVVIVLNQPHE---DKSHIYWPINKSIRYQFFVVDPVVEYNMPNYILREFKVTDARDGEFRALRQFQFTQWPNHGCPKESESILDFIRQVHKTKEQFGHMEPMVIHCNTGSGRTGVFIALSIVLDRLQQESVVDMYQTVKLLHKQRIGLVQTEEQYEFCYMAVLDYLSNYE 5814
SD +++R + ++ + D P I I +L + LKAND E+E+++ +FTW+ SN + NK KNRYANV+AYDH+ VLLT +D V GSDYINANYIDGY++QNAYIATQGPLP+T DFWRMVWEQR +VMMTRLEE+S +KC QYWP RG YG + V+ +DT LA YT+R F + S SEKRE++ FQF AWPDHGVP+ TP+L F+RRV++ +++ P +VHCSAGVGRTG FIV+DA LER+K EK +D++ +V+ +R QRNYMVQT+ QY FI E LLEA G+TEV+A N +AH+ KL Q+ S ++ E+EF KL LA ++ R + F+ A N N KNR+ NI+PYE RV L IRG+EGSDYINAS++DGYR ++AYIA Q P+ + EDFWRMLW+ + ++++L + E +K H YWP +S RYQ+FVVDP+ EYNMP YILREFKVTDARDG+ R +RQFQFT WP G PK E +DFI QVHKTKEQFG P+ +HC+ G GRTGVFI LSIVL+R++ E VVDM+QTVK L QR +VQTE+QY+ CY A L+YL +++
Sbjct: 1302 SDPVEMRRLNYQTPGMRDHPPIPITDLADNIERLKANDGLKFSQEYESIDPG--QQFTWENSNSEVNKPKNRYANVIAYDHSRVLLTSIDGVPGSDYINANYIDGYRKQNAYIATQGPLPETMGDFWRMVWEQRIATVVMMTRLEEKSRVKCDQYWPARGTETYGLIQVTLVDTVELATYTMRTFALHKSGSSEKRELRQFQFMAWPDHGVPEYPTPILAFLRRVKACNPLDAGPMVVHCSAGVGRTGCFIVIDAMLERMKHEKTVDIYGHVTCMRSQRNYMVQTEDQYVFIHEALLEAAMCGHTEVLARNLYAHIQKLGQVPPGES--VTAMELEF-KL--LAGSKAR----ASRFISA--NLPCNKFKNRLVNIMPYELTRVCLQPIRGVEGSDYINASFLDGYRQQKAYIATQGPLAESTEDFWRMLWEHNSTIIVMLTKLREMGREKCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDARDGQSRTIRQFQFTDWPEQGVPKTGEGFIDFIGQVHKTKEQFGQDGPITVHCSAGVGRTGVFITLSIVLERMRYEGVVDMFQTVKTLRTQRPAMVQTEDQYQLCYRAALEYLGSFD 1894 HSP 2 Score: 159.458 bits (402), Expect = 1.670e-37 Identity = 227/964 (23.55%), Postives = 382/964 (39.63%), Query Frame = 1
Query: 277 NSQITFTENDEAPK----ISLIIQSPNVLLFKSMILACSSTGHPVPSISWKINESPIEELKSPLKKLQNPPRIFSIKNYQNSVLVITQLIESDSNSVLICEAENNAGFD-SRQQQLKVISTETDIPSGFPVFQNNFFPIIKPYNSNVTLVCQAYGNPPPLIQWFKNYELINESFTKIKILNDGN--LLLVQVTREDKGIYHCQAQNTNGLRLSDPSTLDITSYPISPNSLIIERFASDNVEISWRSGLNDVTEQENFI-LHYREVPENITEKQIMSKFVYLTISEKKSIYKYNLKDLFPFTTYCIWMESENPLGVSPPTIALTVKTLPTSPQLSPRSITATSISNTAILVAWRPPERKFGKFKYYQIIYTNNDGFLPQHWRQFAVKDDNVMLT---HLIASELYHIRVKIVNEIGHGPLSKTISIKTIAGTLSQCPDFKITEIFQSHIKLQWGTPDPVKLFKLIQYNLLCWDVRLKIVNATAKSSTLFPILNHNLSMNEMEYVLYLKNEKEIKCRLSAINSDGKGM--PTEIQASTVNKGVNY-QNLIHIDKIGSTYITFQWRPPSKFSFDYFLWIYQIFDSEKLDRAVKLPKIKINISDSASAENGWFVYNYTNAFSSSRYILGL------RYLCRDSTDILREYVHRSDLVSTMKSVPSDSPKDLVVKEIDSNSALVSWKPLDQVHSNGIITHYEVRYY-----APKKEESTERFINVSETSAILSNL-KYFHYVIYVRAFTKVGGGSWSNPKNYYRQNLEEFPIPTTIKGERKSETEINISWELPVLSEKNLAHAAIEGFIILYAPV-ESSPKWIKYTVQSKNLSAVIKGLEPDLRYQFQIAATNYAGFNGNFSEIV---QEMPKNFPNLNLKTVPDLRCSVQSSNRLKVEWSSPSISTDLLKFEIRYSGNLSYITEIGLKKSEFIDMESKSVNFETLVNRYDVTLENLQSNALYKIAVRA 3078
+++++ E D+ P I + Q V ++ + C++ G+P P ISW + P++ S + IK ++ L I ESD C A N+AG S L V P P NV L C A G P P ++W + E TK + G L L V R Y C A ++ G+ + + + + + P P L++ + +V ++W SG TE +F + YR + +++ + + +Y++ L PF+ Y + + N +G PP+ A+ +T +P PR + A +S + +LV W PPE G + Y++ YT + W + D +LT L+ Y +RV +G GP S TI +KT G +Q DF+ + I+L W P ++I+Y L+ W + T P ++ L LK + +L+A + G G+ PT ++A T + + GST + W PP S + + Y + AV K ++ D S E+ SS +LGL R R TD+ LV T + VPS P+ + V+ ++S + VSWK +G I Y+V Y P+ + + + +S L Y I V A+T G G+ S PK PT + T + + W P K L + G+ + Y E+ P I + ++ + + GL Y F++AA N AG F + + ++ P FP +LR + +++ ++ W P ++ +G ++ T + + D+ S+ + + +TL L+ + Y I VRA
Sbjct: 119 SAKLSVLEEDQLPSGFPTIDMGPQLKVVEKARTATMLCAAGGNPDPEISWFKDFLPVDPASSNGR----------IKQLRSGALQIESSEESDQGK-YECVATNSAGTRYSAPANLYVRVRRVAPRFSIPPSSQEVMP-----GGNVNLTCVAVGAPMPYVKWM----MGAEELTKEDEMPVGRNVLELSNVMRSAN--YTCVAISSLGM-IEATAQVTVKALPKPPIDLVVTETTATSVTLTWDSG---NTEPVSFYGIQYRAAGTDGPFQEV----------DGVASTRYSIGGLSPFSEYAFRVLAVNSIGRGPPSEAVRARTGEQAPSSPPRRVQARMLSASTMLVQWEPPEEPNGLVRGYRVYYTPDSRRPLSAWHKH--NTDAGLLTTVGSLLPGITYSLRVLAFTAVGDGPPSPTIQVKTQQGVPAQPADFQAKAESDTRIQLSWLLP---PQERIIKYELVYWAAEDE---GQQHKVTFDPTSSYTLE--------DLKPDTLYHFQLAARSDLGVGVFTPT-VEACTAQSTPSAPPQKVTCVSTGSTTVRVSWVPPPADSRNGIITQYSV-----AYEAVDGEDRKRHVVDGISREH------------SSWDLLGLEKWTEYRVWVRAHTDVGPGPESSPVLVRTDEDVPSGPPRKVEVEPLNSTAVHVSWKLPVPNKQHGQIRGYQVTYVRLENGEPRGQPIIQDVMLAEAQETTISGLTPETTYSITVAAYTTKGDGARSKPKVVTTTGAVPG-RPTMMVSTTAMHTAL-LQWHPP----KELP-GELLGYRLQYRRADEARPNTIDFGKDDQHFT--VTGLHKGATYIFRLAAKNRAGPGEEFEKEITTPEDAPSGFPQ-------NLRVTGLTTSTTELAWDPPVLA--------ERNGRITNYTVV------YRDINSQH-ELQNVTGDVHLTLLGLKPDTTYDIKVRA 981 HSP 3 Score: 156.762 bits (395), Expect = 1.153e-36 Identity = 224/999 (22.42%), Postives = 374/999 (37.44%), Query Frame = 1
Query: 370 LACSSTGHPVPSISWKINESPIEELKSPLKKLQNPPRIFSIKNYQNSVLVITQLIESDSNSVLICEAENNAGFDSRQQQLKVISTETDIPSGFPVFQNNFFPIIKPYNS--NVTLVCQAYGNPPPLIQWFKNYELINESFT--KIKILNDGNLLLVQVTREDKGIYHCQAQNTNGLRLSDPSTLDITSYPISPNSLII----ERFASDNVEIS------------WRSGLNDVTEQENFILHYREVPENITE-KQIMSKFVYLTISEKKSIYKYNLKDLFPFTTYCIWMESENPLGVSPPTIALTVKTLPTSPQLSPRSITATSISNTAILVAWRPPERKFGKFKYYQIIYTNNDGFLPQHWRQFAVKDDNVMLTHLIASELYHIRVKIVNEIGHGPLSKTISIKTIAGTLSQCP-DFKITEIFQSHIKLQWGTPDPVKLFKLIQYNLLCWDVRLKIVNATAKSSTLFPILNHNLSMNEMEYVLYLKNEKEIKCRLSAINSDGKGMPTEIQASTVNKGVNYQNLIHIDKIGS-TYITFQW-RPPSKFSFDYFLWIYQIFDSEKLDRAVKLPKIKINISDSASAENGWFVYNYTNAFSSSRYILGLRYLCRDSTDILREYVHRSDLVSTMKSVPSDSPKDLVVKEIDSNSALVSWKPLDQVHSNGIITHYEVRYYAPKKEESTERFIN--VSETSA--ILSNLKYFHYVIYVRAFTKVGGGSWSNPKNYYRQNLEEFP--IPTTIKGERKSETEINISWELPVLSEKNLAHAAIEGFIILYAPVESSPKWIKYTVQSKNLS----AVIKGLEPDLRYQFQIAATNYAGFNGNFSEIVQEMPKNFPNLNLKTVPDLRCSVQSSNRLKVEWSSP-SISTDLLKFEIRYSGNLSYITEIGLKKSEFIDMESKSVNFETLVNRYDVTLENLQSNALYKIAVRAIYQNKELYESHRETTCDTMPAVPNLVKPPIIVGLDEEKSKVIIKLHRCSQRNGKISYYFVI 3261
C +TG P P I+W +K K + + SVL I L ++ C A N+ G + +L V+ E +PSGFP + P +K T++C A GNP P I WFK++ ++ + + +IK L G L + D+G Y C A N+ G R S P+ L + ++P I E NV ++ W G ++T+++ V N+ E +M Y C+ + S LG+ T +TVK LP P + T + T++ + W + F Q DG + V + L Y RV VN IG GP S+ + +T S P + + S + +QW P+ + N L R+ + + + + HN + V L R+ A + G G P+ +GV Q K S T I W PP + Y L + D + + P + D +Y++ A +R LG+ + V T +S PS P+ + S + VSW P NGIIT Y V Y A E+ ++ E S+ +L K+ Y ++VRA T VG G S+P + E+ P P ++ E + T +++SW+LPV N H I G+ + Y +E+ + +Q L+ I GL P+ Y +AA G V P P + S + + ++W P + +LL + ++Y ++++ + +++F + VT + + ++++A + E +E T D P ++ + GL +++ ++RNG+I+ Y V+
Sbjct: 52 FVCQATGEPKPRITW---------MKKGKKVSSQRFEVIEFDDGAGSVLRIQPLRVQRDEAIYECTATNSLGEINTSAKLSVLE-EDQLPSGFPTI--DMGPQLKVVEKARTATMLCAAGGNPDPEISWFKDFLPVDPASSNGRIKQLRSGALQIESSEESDQGKYECVATNSAGTRYSAPANLYVRVRRVAPRFSIPPSSQEVMPGGNVNLTCVAVGAPMPYVKWMMGAEELTKEDEM-----PVGRNVLELSNVMRSANYT----------------------CVAISS---LGMIEATAQVTVKALPKPPI----DLVVTETTATSVTLTWDSGNTEPVSFYGIQYRAAGTDGPFQE---VDGVASTRYSIGGLSPFSEYAFRVLAVNSIGRGPPSEAVRARTGEQAPSSPPRRVQARMLSASTMLVQWEPPE--------EPNGLVRGYRVYYTPDSRRPLSAW--HKHNTDAGLLTTVGSLLPGITYSLRVLAFTAVGDGPPSPTIQVKTQQGVPAQPADFQAKAESDTRIQLSWLLPPQERIIKYELVYWAAEDEGQQHKVTFDPTSSYTLEDLKPDT----LYHFQLA---ARSDLGV--------GVFTPTVE----ACTAQSTPSAPPQKVTCVSTGSTTVRVSWVPPPADSRNGIITQYSVAYEAVDGEDRKRHVVDGISREHSSWDLLGLEKWTEYRVWVRAHTDVGPGPESSP--VLVRTDEDVPSGPPRKVEVEPLNSTAVHVSWKLPV---PNKQHGQIRGYQVTYVRLENGEPRGQPIIQDVMLAEAQETTISGLTPETTYSITVAAYTTKGDGARSKPKVVTTTGAVPGR-----PTMMVSTTAMHTALLQWHPPKELPGELLGYRLQY------------RRAD--EARPNTIDFGKDDQHFTVTGLHKGATYIFRLAAKNRAGPGEEFEKEITTPEDAPSGFPQNLR---VTGLTTSTTELAWDPPVLAERNGRITNYTVV 945 HSP 4 Score: 62.7734 bits (151), Expect = 3.810e-8 Identity = 64/295 (21.69%), Postives = 125/295 (42.37%), Query Frame = 1
Query: 1096 TISEKKSIYKYNLKDLFPFTTYCIWMESENPLGVSPPTIALTVKTLPTSPQLSPRSITATSISNTAILVAWRPP--ERKFGKFKYYQIIYTNNDGFLPQHWRQFAVKDDNVMLTHLIASELYHIRVKIVNEIGHGPLSKTISIKTIAGTLSQCPDFKITEIFQSHIKLQWGTPDPVK---LFKLIQYNLLCWDV-----RLKIVNATAKSSTLFPILNHNLSMNEMEYVLYLKNEKEI----KCRLSAINSDGK---GMPTEIQASTVNKGVNYQNLIHIDKIGSTYITFQWRPP 1929
TI K + + L TY + ++N G + T +P P+++ T ++ + +AW PP + G+ Y ++Y + + QH Q D ++ L L Y I+V+ G GPLS +I +T+ +F++ ++ + L W PD K FK++ YN +V R I + + F ++N S +++++ ++ ++ SA DG+ MP ++Q ++ + Y ++ ID++G + +W P
Sbjct: 858 TIDFGKDDQHFTVTGLHKGATYIFRLAAKNRAGPGE-EFEKEITTPEDAPSGFPQNLRVTGLTTSTTELAWDPPVLAERNGRITNYTVVYRDINS---QHELQNVTGDVHLTLLGLKPDTTYDIKVRAHTSKGAGPLSPSIQSRTMPMEQVFAKNFRVAAAMKTSVLLSWEVPDSYKSAVPFKIL-YNGQSVEVDGHSMRKLIADLQPNTEYSFVLMNRGTSAGGLQHLVSIRTAPDLLPQKPLPASAFIEDGRFSLSMP-QVQDPSLVRWF-YIVVVPIDRVGGNLLAPRWSTP 1145
BLAST of Protein tyrosine phosphatase receptor type D vs. TrEMBL
Match: A0A267H9B7 (Uncharacterized protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig026250g1 PE=4 SV=1) HSP 1 Score: 793.882 bits (2049), Expect = 0.000e+0 Identity = 488/1289 (37.86%), Postives = 695/1289 (53.92%), Query Frame = 1
Query: 2164 SDLVSTMKSV----PSDSPKDLVVK-EIDSNSALVSWKPLDQVHSNGIITHYEVRYYAPKK--EESTERFINVSETSAILSNLK-YFHYVIYVRAFTKVGGGSWSNPKNYYRQNLEEFPIPTTIKG---ERKSETEINISWELPVLSEK------NLAHAAIEGFIILYAPVESSPKWIKYTVQSKNLSA---VIKGLEPDLRYQFQIAATNYAGFNGNFSEIVQEMPKNFPNLNLKTVPDLRCSVQSSNRLKVEWSSPSISTDLLKFEIRYSGNLSYITEIGL--KKSEFIDMESKSVNFETLVNRYDVTLENLQSNALYKIAVRAIYQNKELYESHRETTCDTMPAVPNLVKPPIIVGLDEEKSKVIIKLHRCSQRNGKISYYFVIVAA-FQGNKNQQISFQE-DTESYTFMELSVNTRSNNAKGEYIAIMKDINDIFKVSGKDHSSVL-------LGDGTHDENHLSVNKKLEKNFNYRCFARVCLKYSNN--------SLCKSSPWSEPFRISDLILNRNVXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXASIIIGCIVKRKKSKERFMHL----GNHDDIRSSIGM--KSSMLNGLMAADK-----IFVSAEVDEPFNS-----------------DKKYTSMSLKPDIKSIPDLVNADSVQMCQDGTKL--SPVLVSDSIKLRIGSQKSENISDRPSISICNLYQYVTDLKANDCTLLQAEFETLNTNLDDRFTWQRSNIDSNKSKNRYANVVAYDHTSVLLTPVDDVIGSDYINANYIDGYQRQNAYIATQGPLPDTTDDFWRMVWEQRSNCIVMMTRLEERSGIKCHQYWPNRGFICYGQMIVSHIDTFVLAYYTIRLFEIRHSKYSEKREIQHFQFTAWPDHGVPKLSTPLLMFIRRVRSIGKIESCPKIVHCSAGVGRTGAFIVVDAQLERIKQEKNIDVFNYVSKIRCQRNYMVQTQAQYQFILETLLEAVEDGNTEVMACNFHAHVTKLSQIGISGSNQLSGFEMEFSKLNSLASNRGRHGVMLADFVKAAGNQAVNMTKNRVRNIIPYEWNRVVLNAIRGIEGSDYINASYIDGYRDRRAYIAAQSPIPSTVEDFWRMLWDQHCGVVIVLNQPHE---DKSHIYWPINKSIRYQFFVVDPVVEYNMPNYILREFKVTDARDGEFRALRQFQFTQWPNHGCPKESESILDFIRQVHKTKEQFGHMEPMVIHCNTGSGRTGVFIALSIVLDRLQQESVVDMYQTVKLLHKQRIGLVQTEEQYEFCYMAVLDYLSNYE 5814
D++S +V PS P+ V + D++ + + KP+ NG IT+ EV Y+ PK + + +V +SA++ +L Y+ VRA+ G G WS+ + P G R S T I W LP + A +AI IL++P +P +Q+ + +++ L+ Y + + G +G+ V E P N + +LRC + + L + W P S L FE Y+ +I + G + + ++++ + L+ L N LY I + A + N+E + E C T A P ++ PI + D ++ + ++L R S R G + Y ++VA Q +Q + FQ D E+ +SV+ R ++K YIA ++S + + L T D ++NK L + +Y+ F CL + + + C SPWSE F + +R++ + S + + L I I +GC V +K ER + G H + R + + + S+ L+ A + +A S +++ ++ + ++P L S++ P +D ++LR + ++ ++ P + + L +V LKA+D AE+E+++ +FTW+ SN+D NK KNRYANV+AYDH+ V+L P+D + GSDYINANY+DGY+RQNAYIATQGPLPDT DFWRM+WEQ+++ +VMMTRLEERS +KC YWPN+G + M VS +DT LAYYTIR F + + +EKREI HFQFTAWPDHGVP+ PLLMF RRVR+ ++ P +VHCSAGVGRTGAFIV+DA LER+KQEK +DV+ +V+ +R QRNYMVQT+ QY FI + LLEAV GNTEV A A V +LS I + +G E+EF L H A N KNR+ NI+P+E NRV L IRG+EGSDYINAS+IDGYR R YIA Q P+P T EDFWRMLW+ + +V+ L + E DK H YWP +S RYQ+FVVDP+ EYNMPNYILREFKVTDARDG+ R +RQF T WP G PK E ++FI QVHKTKEQFG P+ +HC+ G GRTGVF+ALS+VL+R++ E VVDMYQTV+ L QR +VQT+EQY+FCY A L+YLS+++
Sbjct: 828 GDVISCQATVREAPPSMKPESFSVNTKSDTSVEVFALKPI-LTGRNGQITNTEVAYW-PKNAIDGYGSKNFSVENSSAVIRHLNPSREYLFKVRAWNSAGPGPWSDVMPVRTRQQPAPQSPAPPAGIVVSRVSPTRARIDWSLPPPPPPPQQPPVSAAQSAIADLRILFSPDPGAPVEAFQQLQAGGVPDRPFILENLDSSAEYTLRF---QWIGADGSPVGPVSE-PHLLRLFNREAPRELRCFDRRPDSLGLRWLRPHDSAGLESFEYNYTATGRFIDDSGQEQRSRRLSPVMPVPLSWDAQPAEFQHMLKGLDPNKLYTIRLTARFPNRE---ASAEVACPTASAPPRSLQAPIAIDKDVDRRLITLRLRRASDRLGVVQRYLLVVAPEAQSATSQDLLFQRSDLET-----VSVDARIGSSKEPYIAACFTAQRFRQLSSPQSAGYIEFQLGTKLPTETCDSRQQALNKPLLSDASYKSFLAACLSPAGSGPVGSLVGAGCSYSPWSEAFGTHIALPSRSLGTAESGYFTLIVVLVTSALGLTAVVCISV-GCIALGCFVCGRKGTERGRNFRNGSGGHSNNRQPMQVLVEPSLKQPLIPASQQNSTSFCATAATGGTLQSVVGSATLQRQQQQQQQQQQQFGTLQSSSHVGTLPTL----SIRSASSSAAFHQGP---TDPVELRRINFQTPALTGHPPVPVAQLIDHVASLKASDNLKFSAEYESIDPG--QQFTWENSNLDVNKPKNRYANVIAYDHSRVVLQPLDGLPGSDYINANYMDGYRRQNAYIATQGPLPDTIGDFWRMIWEQKTSTVVMMTRLEERSRVKCDMYWPNKGSEVFDYMTVSLLDTLELAYYTIRTFALHRAGATEKREIHHFQFTAWPDHGVPEHCAPLLMFARRVRASNPPDAGPIVVHCSAGVGRTGAFIVIDAMLERMKQEKTLDVYGHVTCLRAQRNYMVQTEDQYIFIHDCLLEAVICGNTEVPARALAAQVQRLS-IPEPAAGGATGMELEFRSLAHTVKPTPAHKFTSASL-------PANKLKNRLVNILPFESNRVCLQPIRGVEGSDYINASWIDGYRQRSCYIATQGPLPDTAEDFWRMLWEHNSTIVVNLTKLREQGRDKCHQYWPGERSARYQYFVVDPMAEYNMPNYILREFKVTDARDGQSRTVRQFHCTDWPEQGVPKSGEGFIEFIGQVHKTKEQFGQDGPITVHCSAGVGRTGVFLALSVVLERMRYEGVVDMYQTVRTLRTQRSAMVQTDEQYQFCYGAALEYLSSFD 2084 HSP 2 Score: 107.457 bits (267), Expect = 3.280e-19 Identity = 171/734 (23.30%), Postives = 291/734 (39.65%), Query Frame = 1
Query: 685 PYNSNVTLVCQAYGNPPPLIQWF--KNYELINESFTKIKILNDGNLLLVQVTREDKGIYHCQAQNTNGLRLSDPSTLDITSYPISPNSLIIERFASDNVEISWRSGLNDVTEQENFILHYREVPENITEKQIMSKFVYLTISEKKSIYKYNLKDLFPFTTYCIWMES-----ENPLGVSPPTIALTVKTLPTSPQLSPRSITATSISNTAILVAWRPPERKFGKFKYYQIIYT---------NNDGFLPQHWRQFAVKDDNVMLTHLIASELYHIRVKIVNEIGHGPLSKTISIKTIAGTLSQCPDFKITEIFQSHIKLQWGTPDPVKLFKLIQYNLLCWDVRLKIVNATAKSSTLFPILNHNLSMNEMEYVLY-LKNEKEIKCRLSAINSDGKGMPTEI---QAS--TVNKGVNYQNLIHIDKIGSTYITFQWRPPSKFSFDYFLWIYQIF-DSEKLDRAVKLPKIKINISDSASAENGWFVYNYTNAFSSSRYILGLRYLCRDSTDILREYVHRSDLVSTMKSVPSDSPKDLVVK-----EIDSNSALVSWKPLDQVHSNGIITHYEVRYYA--PKKEESTERFINV----SETSAILSNLKYFHYVIY---VRAFTKVGGGSWSNPKNYYRQNLEEFPIPTTIKGERKSETEINISWELPVLSEKNLAHAAIEGFIILYAPVESSPKWIKYTVQSKNLSAVIKGLEPDLRYQFQIAATNYAGFNGNFSEIV 2775
P SNV L C A G P P +QWF K +L K +I L+L VT +D Y CQAQN+ G + ++ + P P+ L + + A VEI ++ + +++ + YRE ++ + + +E + + L P T Y + ++S + S P + TL T P +P+ I ++S + +AW+ P+ G Y+I YT N +P R +KD L + Y+ R+ N +G GP+S + T+ G S+ F+ I+L W +LI Y L + + + + P+ N+ Y+L L+ L+ GKG+PTE Q S T K VN Q + I W PP + + W+ + + ++ + AV + K + + E G++ Y + + Y +G+ + + Y + V+T+ VPS +PK ++ S S ++W D + + I Y + Y A P S+ + V TS L K +Y + A G G + + R+ P + KS+T + + P+L+ +N I + Y P + + +N SAVI+ L P Y F++ A N AG G +S+++
Sbjct: 236 PAGSNVNLTCVAVGAPMPRVQWFDSKGTDLGTNEPGKQQI-GRFVLMLTDVTSDDN--YTCQAQNSLGT-IHWMVSVTVQKMPEPPSDLQVIKHAPTTVEIEFKK--SRTPGVQSYTVSYREEASRTMNRRNWIQIENVPGNEPGDRVRTRVSSLRPHTKYQLKVDSVTANFSSKDNTSNPIVEFM--TLETFPAKAPKDIQVVAVSRADVNIAWKEPDDPNGIITKYRIYYTTERVTNIDSNIKVEVPGTQRMHTIKD-------LEYNTTYYFRMTASNMVGEGPVSDVYPVITVVGIASRPKGFQCATTGHDSIQLSWDPAASSDKGRLISYILSYKSSAIYLEDGMETREEVLPV------DNDSGYLLKNLRPGTTYHLTLTPSTEQGKGIPTETIVCQTSDFTPGKPVNVQ----ARALQGQQIEVTWSPPLE-ARGIQQWLVRYYRATDPMGTAVPSEETKKVVPN--LVEQGFYRYVISGLEPKTAYHIGVAASSGPAGGV-SSYESIREPVTTLGLVPS-APKRFEASVRYDPDLRSASIDLNWLAPDTLRGSR-IEEYRLLYRAVGPPDLVSSRTYTEVPLSHGRTSWTLPPNKVLFGAVYNFSLSAKNNEGYGDVISCQATVREAPPSMK-PESFSVNTKSDTSVEVFALKPILTGRN---GQITNTEVAYWPKNAIDGYGSKNFSVENSSAVIRHLNPSREYLFKVRAWNSAG-PGPWSDVM 933
BLAST of Protein tyrosine phosphatase receptor type D vs. TrEMBL
Match: A0A267DSI9 (Uncharacterized protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig026250g3 PE=4 SV=1) HSP 1 Score: 791.571 bits (2043), Expect = 0.000e+0 Identity = 487/1288 (37.81%), Postives = 697/1288 (54.11%), Query Frame = 1
Query: 2164 SDLVSTMKSV----PSDSPKDLVVK-EIDSNSALVSWKPLDQVHSNGIITHYEVRYYAPKK--EESTERFINVSETSAILSNL-KYFHYVIYVRAFTKVGGGSWSNPKNYYRQNLEEFPIPTTIKG---ERKSETEINISWELPVLSEK-----NLAHAAIEGFIILYAPVESSPKWIKYTVQSKNL---SAVIKGLEPDLRYQFQIAATNYAGFNGNFSEIVQEMPKNFPNLNLKTVPDLRCSVQSSNRLKVEWSSPSISTDLLKFEIRYSGNLSYITEIGLKKS--EFIDMESKSVNFETLVNRYDVTLENLQSNALYKIAVRAIYQNKELYESHRETTCDTMPAVPNLVKPPIIVGLDEEKSKVIIKLHRCSQRNGKISYYFVIVAA-FQGNKNQQISFQE-DTESYTFMELSVNTRSNNAKGEYIAIMKDINDIFKVSGKDHSSVL-------LGDGTHDENHLSVNKKLEKNFNYRCFARVCLKYSNN--------SLCKSSPWSEPFRISDLILNRNVXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXASIIIGCIVKRKKSKERFMHL----GNHDDIRSSIGM--KSSMLNGLMAADK-----IFVSAEVDEPFNS-----------------DKKYTSMSLKPDIKSIPDLVNADSVQMCQDGTKL--SPVLVSDSIKLRIGSQKSENISDRPSISICNLYQYVTDLKANDCTLLQAEFETLNTNLDDRFTWQRSNIDSNKSKNRYANVVAYDHTSVLLTPVDDVIGSDYINANYIDGYQRQNAYIATQGPLPDTTDDFWRMVWEQRSNCIVMMTRLEERSGIKCHQYWPNRGFICYGQMIVSHIDTFVLAYYTIRLFEIRHSKYSEKREIQHFQFTAWPDHGVPKLSTPLLMFIRRVRSIGKIESCPKIVHCSAGVGRTGAFIVVDAQLERIKQEKNIDVFNYVSKIRCQRNYMVQTQAQYQFILETLLEAVEDGNTEVMACNFHAHVTKLSQIGISGSNQLSGFEMEFSKLNSLASNRGRHGVMLADFVKAAGNQAVNMTKNRVRNIIPYEWNRVVLNAIRGIEGSDYINASYIDGYRDRRAYIAAQSPIPSTVEDFWRMLWDQHCGVVIVLNQPHE---DKSHIYWPINKSIRYQFFVVDPVVEYNMPNYILREFKVTDARDGEFRALRQFQFTQWPNHGCPKESESILDFIRQVHKTKEQFGHMEPMVIHCNTGSGRTGVFIALSIVLDRLQQESVVDMYQTVKLLHKQRIGLVQTEEQYEFCYMAVLDYLSNYE 5814
D++S +V PS P+ V + D++ + + KP+ NG IT+ EV Y+ PK + + +V +SA++ +L Y+ VRA+ G G WS+ + P+ G R S T I W LP + A +AI IL++P +P +Q+ + +++ L+ Y + + G +G+ V E P N + +LRC + + L + W P S L FE Y+ +I + G ++ + ++++ + L+ L N LY I + A + N+E + E C T A P ++ PI + D ++ + ++L R S R G + Y ++VA Q +Q + FQ D E+ +SV+ R ++K YIA ++S + + L T D ++NK L + +Y+ F CL + + + C SPWSE F + +R++ + S + + L I I +GC V +K ER + G H + R + + + S+ L+ A + +A S +++ ++ + ++P L S++ P +D ++LR + ++ ++ P + + L +V LKA+D AE+E+++ +FTW+ SN+D NK KNRYANV+AYDH+ V+L P+D + GSDYINANY+DGY+RQNAYIATQGPLPDT DFWRM+WEQ+++ +VMMTRLEERS +KC YWPN+G + M VS +DT LAYYTIR F + + +EKREI HFQFTAWPDHGVP+ PLLMF RRVR+ ++ P +VHCSAGVGRTGAFIV+DA LER+KQEK +DV+ +V+ +R QRNYMVQT+ QY FI + LLEAV GNTEV A + V +LS I + +G E+EF L H A N KNR+ NI+P+E NRV L IRG+EGSDYINAS+IDGYR R YIA Q P+P T EDFWRMLW+ + +V+ L + E DK H YWP +S RYQ+FVVDP+ EYNMPNYILREFKVTDARDG+ R +RQF T WP G PK E ++FI QVHKTKEQFG P+ +HC+ G GRTGVF+ALS+VL+R++ E VVDMYQTV+ L QR +VQT+EQY+FCY A L+YLS+++
Sbjct: 140 GDVISCQATVREAPPSMKPESFSVNTKSDTSVEVFALKPI-LTGRNGHITNTEVAYW-PKNAIDGYGSKNFSVENSSAVIRHLNPSREYLFKVRAWNSAGPGPWSDVMPVRTRQQPPPQSPSPPAGIVLSRVSPTRARIDWSLPPPPPPQQPPVSAAQSAIADLRILFSPDPGAPVEAFQQLQAGGVLDRPFILENLDSSAEYTLRF---QWIGADGSPVGPVSE-PHLLRLFNREAPRELRCFDRRPDSLGLRWLRPHDSAGLESFEYNYTATGRFIDDSGQEQRSRRLSPVMPVPLSWDAQPAEFQHVLKGLDPNKLYTIRLTARFPNRE---ASAEVACPTASAPPRSLQAPIAIDKDVDRRLITLRLRRASDRLGVVQRYLLVVAPEAQSATSQDLLFQRSDLET-----VSVDARIASSKEPYIAACFTAQRFRQLSSPQSAGYIEFQLGTKLPTETCDSRQQALNKPLLSDASYKSFLAACLSPAGSGPVGSLVGAGCSYSPWSEAFGTHIALPSRSLGTAESGYFTLIVVLVTSALGLTAVVCISV-GCIALGCFVCGRKGTERGRNFRNGSGGHSNNRQPMQVLVEPSLKQPLIPASQQNSTSFCATAATGGTLQSVVGSATLQRQQQQQQQQQQQFGTLQSSSHVGTLPTL----SIRSASSSAAFHQGP---TDPVELRRINFQTPALTSHPPVPVAQLIDHVASLKASDNLKFSAEYESIDPG--QQFTWENSNLDVNKPKNRYANVIAYDHSRVVLQPLDGLPGSDYINANYMDGYRRQNAYIATQGPLPDTIGDFWRMIWEQKTSTVVMMTRLEERSRVKCDMYWPNKGSEVFDYMTVSLLDTLELAYYTIRTFALHRAGATEKREIHHFQFTAWPDHGVPEHCAPLLMFARRVRASNPPDAGPIVVHCSAGVGRTGAFIVIDAMLERMKQEKTLDVYGHVTCLRAQRNYMVQTEDQYIFIHDCLLEAVICGNTEVPARALASQVQRLS-IPEPAAGGATGMELEFRSLAHTVKPTPAHKFTSASL-------PANKLKNRLVNILPFESNRVCLQPIRGVEGSDYINASWIDGYRQRSCYIATQGPLPDTAEDFWRMLWEHNSTIVVNLTKLREQGRDKCHQYWPGERSARYQYFVVDPMAEYNMPNYILREFKVTDARDGQSRTVRQFHCTDWPEQGVPKSGEGFIEFIGQVHKTKEQFGQDGPITVHCSAGVGRTGVFLALSVVLERMRYEGVVDMYQTVRTLRTQRSAMVQTDEQYQFCYGAALEYLSSFD 1395
BLAST of Protein tyrosine phosphatase receptor type D vs. TrEMBL
Match: A0A267G0Z1 (Uncharacterized protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig026250g5 PE=4 SV=1) HSP 1 Score: 751.125 bits (1938), Expect = 0.000e+0 Identity = 417/978 (42.64%), Postives = 570/978 (58.28%), Query Frame = 1
Query: 3031 LENLQSNALYKIAVRAIYQNKELYESHRETTCDTMPAVPNLVKPPIIVGLDEEKSKVIIKLHRCSQRNGKISYYFVIVAA-FQGNKNQQISFQE-DTESYTFMELSVNTRSNNAKGEYIAIMKDINDIFKVSGKDHSSVL-------LGDGTHDENHLSVNKKLEKNFNYRCFARVCLKYSNN--------SLCKSSPWSEPFRISDLILNRNVXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXASIIIGCIVKRKKSKERFMHL----GNHDDIRSSIGM--KSSMLNGLMAADK-----IFVSAEVDEPFNS-----------------DKKYTSMSLKPDIKSIPDLVNADSVQMCQDGTKL--SPVLVSDSIKLRIGSQKSENISDRPSISICNLYQYVTDLKANDCTLLQAEFETLNTNLDDRFTWQRSNIDSNKSKNRYANVVAYDHTSVLLTPVDDVIGSDYINANYIDGYQRQNAYIATQGPLPDTTDDFWRMVWEQRSNCIVMMTRLEERSGIKCHQYWPNRGFICYGQMIVSHIDTFVLAYYTIRLFEIRHSKYSEKREIQHFQFTAWPDHGVPKLSTPLLMFIRRVRSIGKIESCPKIVHCSAGVGRTGAFIVVDAQLERIKQEKNIDVFNYVSKIRCQRNYMVQTQAQYQFILETLLEAVEDGNTEVMACNFHAHVTKLSQIGISGSNQLSGFEMEFSKLNSLASNRGRHGVMLADFVKAAGNQAVNMTKNRVRNIIPYEWNRVVLNAIRGIEGSDYINASYIDGYRDRRAYIAAQSPIPSTVEDFWRMLWDQHCGVVIVLNQPHE---DKSHIYWPINKSIRYQFFVVDPVVEYNMPNYILREFKVTDARDGEFRALRQFQFTQWPNHGCPKESESILDFIRQVHKTKEQFGHMEPMVIHCNTGSGRTGVFIALSIVLDRLQQESVVDMYQTVKLLHKQRIGLVQTEEQYEFCYMAVLDYLSNYE 5814
L+ L N LY I + A + N+E + E C T A P ++ PI + D ++ + ++L R S R G + Y ++VA Q +Q + FQ D E+ +SV+ R ++K YIA ++S + + L T D ++NK L + +Y+ F CL + + + C SPWSE F + +R++ + S + + L I I +GC V +K ER + G H + R + + + S+ L+ A + +A S +++ ++ + ++P L S++ P +D ++LR + ++ ++ P + + L +V LKA+D AE+E+++ +FTW+ SN+D NK KNRYANV+AYDH+ V+L P+D + GSDYINANY+DGY+RQNAYIATQGPLPDT DFWRM+WEQ+++ +VMMTRLEERS +KC YWPN+G + M VS +DT LAYYTIR F + + +EKREI HFQFTAWPDHGVP+ PLLMF RRV + ++ P + HCSAGVGRTGAFIV+DA LER+KQEK +DV+ +V+ +R QRNYMVQT+ QY FI + LLEAV GNTEV A A V +LS I + +G E+EF L H A N KNR+ NI+P+E NRV L IRG+EGSDYINAS+IDGYR R YIA Q P+P T EDFWRMLW+ + +V+ L + E DK H YWP +S RYQ+FVVDP+ EYNMPNYILREFKVTDARDG+ R +RQF T WP G PK E ++FI QVHKTKEQFG P+ +HC+ G GRTGVF+ALS+VL+R++ E VVDMYQTV+ L QR +VQT+EQY+FCY A L+YLS+++
Sbjct: 18 LKGLDPNKLYTIRLTARFPNRE---ASAEVACPTASAPPRSLQAPIAIDKDVDRRLITLRLRRASDRLGVVQRYLLVVAPEAQSATSQDLLFQRSDLET-----VSVDARIASSKEPYIAACFTAQRFRQLSSPQSAGYIEFQLGTKLPTETCDSRQQALNKPLLSDASYKSFLAACLSPAGSGPVGSLVGAGCSYSPWSEAFGTHIALPSRSLGTAESGYFTLIIVLVTSALGLTAVVCISV-GCIALGCFVCGRKGTERGRNFRNGSGGHSNNRQPMQVLVEPSLKQPLIPASQQNSTSFCATAATGGTLQSVVGSATLQRQQQQQQQQQQQFGTLQSSSHVGTLPTL----SIRSASSSAAFHQGP---TDPVELRRINFQTPALTGHPPVPVAQLIDHVASLKASDNLKFSAEYESIDPG--QQFTWENSNLDVNKPKNRYANVIAYDHSRVVLQPLDGLPGSDYINANYMDGYRRQNAYIATQGPLPDTIGDFWRMIWEQKTSTVVMMTRLEERSRVKCDMYWPNKGSEVFDYMTVSLLDTLELAYYTIRTFALHRAGATEKREIHHFQFTAWPDHGVPEHCAPLLMFARRVHASNPPDAGPIVAHCSAGVGRTGAFIVIDAMLERMKQEKTLDVYGHVTCLRAQRNYMVQTEDQYIFIHDCLLEAVICGNTEVPARALAAQVQRLS-IPEPAAGGATGMELEFRSLAHTVKPTPAHKFTSASL-------PANKLKNRLVNILPFESNRVCLQPIRGVEGSDYINASWIDGYRQRSCYIATQGPLPDTAEDFWRMLWEHNSTIVVNLTKLREQGRDKCHQYWPGERSARYQYFVVDPMAEYNMPNYILREFKVTDARDGQSRTVRQFHCTDWPEQGVPKSGEGFIEFIGQVHKTKEQFGQDGPITVHCSAGVGRTGVFLALSVVLERMRYEGVVDMYQTVRTLRTQRSAMVQTDEQYQFCYGAALEYLSSFD 969
BLAST of Protein tyrosine phosphatase receptor type D vs. TrEMBL
Match: A0A3P8NJL3 (Protein tyrosine phosphatase receptor type Fa OS=Astatotilapia calliptera OX=8154 PE=4 SV=1) HSP 1 Score: 727.243 bits (1876), Expect = 0.000e+0 Identity = 333/606 (54.95%), Postives = 441/606 (72.77%), Query Frame = 1
Query: 4006 SDSIKLRIGSQKSENISDRPSISICNLYQYVTDLKANDCTLLQAEFETLNTNLDDRFTWQRSNIDSNKSKNRYANVVAYDHTSVLLTPVDDVIGSDYINANYIDGYQRQNAYIATQGPLPDTTDDFWRMVWEQRSNCIVMMTRLEERSGIKCHQYWPNRGFICYGQMIVSHIDTFVLAYYTIRLFEIRHSKYSEKREIQHFQFTAWPDHGVPKLSTPLLMFIRRVRSIGKIESCPKIVHCSAGVGRTGAFIVVDAQLERIKQEKNIDVFNYVSKIRCQRNYMVQTQAQYQFILETLLEAVEDGNTEVMACNFHAHVTKLSQIGISGSNQLSGFEMEFSKLNSLASNRGRHGVMLADFVKAAGNQAVNMTKNRVRNIIPYEWNRVVLNAIRGIEGSDYINASYIDGYRDRRAYIAAQSPIPSTVEDFWRMLWDQHCGVVIVLNQPHE---DKSHIYWPINKSIRYQFFVVDPVVEYNMPNYILREFKVTDARDGEFRALRQFQFTQWPNHGCPKESESILDFIRQVHKTKEQFGHMEPMVIHCNTGSGRTGVFIALSIVLDRLQQESVVDMYQTVKLLHKQRIGLVQTEEQYEFCYMAVLDYLSNYE 5814
SD +++R + +++ + + P I++C+L ++ LKAND E+E+++ +FTW+ SN++ NK KNRYANV+AYDH+ V+LTPVD V GSDYINANYIDGY++QNAYIATQGPLP+T DFWRMVWEQR+ IVMMTRLEE+S +KC QYWP+RG YG + V+ +DT LA Y++R F + + SEKRE++ FQF AWPDHGVP+ TP L F+RR++S ++ P +VHCSAGVGRTG FIV+DA LER+K EK++D++ +V+ +R QRNYMVQT+ QY F+ E LLEA GNTEV A N +AH+ KL+Q ++ ++ E+EF KL + ++ R F+ A N N KNR+ NI+P+E RV L IRG+EGSDYINAS+IDGYR ++AY+A Q P+ T EDFWRMLW+ + +V++L + E +K H YWP +S RYQ+FVVDP+ EYNMP YILREFKVTDARDG+ R +RQFQFT WP G PK E +DFI QVHKTKEQFG P+ +HC+ G GRTGVFI LSIVL+R++ E VVD++QTVK L QR +VQTE+QY+ CY A L+YL +++
Sbjct: 1310 SDPVEMRRLNYQTQGMREHPPIAVCDLADHIERLKANDGLHFSQEYESIDPG--QQFTWEHSNLEVNKPKNRYANVIAYDHSRVILTPVDGVPGSDYINANYIDGYRKQNAYIATQGPLPETLSDFWRMVWEQRTCTIVMMTRLEEKSRVKCDQYWPSRGTETYGMIQVTMLDTLELATYSVRTFALYKNGSSEKREVRQFQFLAWPDHGVPEYPTPTLAFLRRIKSCNPQDAGPMVVHCSAGVGRTGCFIVIDAMLERMKHEKSVDIYGHVTCMRAQRNYMVQTEDQYIFVHEALLEAAVCGNTEVPARNLYAHIQKLTQ--VAAGEAVTAMELEFKKLANSKAHTSR-------FISA--NLPCNKFKNRLVNIMPFESTRVCLQPIRGVEGSDYINASFIDGYRQQKAYMATQGPLAETTEDFWRMLWEHNSTIVVMLTKLREMGREKCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDARDGQSRTIRQFQFTDWPEQGVPKTGEGFIDFIGQVHKTKEQFGQDGPITVHCSAGVGRTGVFITLSIVLERMRYEGVVDLFQTVKTLRTQRPAMVQTEDQYQLCYRAALEYLGSFD 1902 HSP 2 Score: 136.346 bits (342), Expect = 5.462e-28 Identity = 232/1019 (22.77%), Postives = 379/1019 (37.19%), Query Frame = 1
Query: 370 LACSSTGHPVPSISWKINESPIEELKSPLKKLQNPPRIFSIKNYQNSVLVITQLIESDSNSVLICEAENNAGFDSRQQQLKVISTETDIPSGFPVFQNNFFPIIKPYNSNVTLVCQAYGNPPPLIQWFKNYEL--INESFTKIKILNDGN-----LLLVQVTRE-DKGIYHCQAQNTNGLRLSDPSTLDI------TSYPISPNSLIIERFASDNVE----------ISWRSGLNDVTEQENFILHYREVPENITEKQIMSKFVYLTISEKKSIYKYNLKDLFPFTTYCIWMESENPLGVSPPTIALTVKTLPTSPQLSPRSITATSISNTAILVAWRP--PERKFGKFKYYQIIYT---NNDGFLPQHWRQFAVKDDNVMLTHLIASEL-----YHIRVKIVNEIGHGPLSKTISIKTIAGTLSQCPDFKITEIFQSHIKL-QWGTPDPVKLFKLIQYNLLCWDVRLKIVNATAKSSTLFPILNHNLSMNEMEYVLYLKNEKEIKCRLSAINSDGKGMPTEIQASTVNKGV-----NYQNLIHIDKIGSTYITFQWRPPSK---FSFDYFLWIYQIFDSEKLDRAVKLPKIKINISDSASAENGWFVYNYTNAFSSSRYILGLRYLCRDSTDILREYVHRSDLVSTMKSVPSDSPKDLVVKEIDSNSALVSW--KPLDQVHSNGIITHYEVRYYAPKKEESTER---FINVSETSAILSNL-KYFHYVIYVRAFTKVGGGSWSNP-KNYYRQNLEEFPIPTTIKGERKSETEINISWELPVLSEKNLAHAAIEGFIILYAPVESSPKWIKYTVQSKNL----SAVIKGLEPDLRYQFQIAATNYAGFNGNFSEIVQEMPKNFPNLNLKTVPDLRCSVQSSNRLKVEWSSP-SISTDLLKFEIRYSGNLSYITEIGLKKSEFIDMESKSVNFETLVNRYDVTLENLQSNALYKIAVRAIYQNKELYESHRETTCDTMPAVPNLVKPPIIVGLDEEKSKVIIKLHRCSQRNGKISYYFVI 3261
C + G P P I+W +K K + + SVL I L ++ C A N+ G + +L V+ E IP GFP + T++C A GNP P I WFK++ I+ S +IK L G L ++ + E D+G Y C A N+ G R S P+ L + + I P + + S N+ + W SG ++T ++ E I + LT N++ +T C+ + S LG+ T +TVK LP P S+T T + T++ + W PE YY I Y + +GF + D V T L Y RV VN +G GP S + +T S P + S L QW P+ ++ Y ++ ++ + L HN + + L + R+ S G G P++ +GV ++ +D + I W P + SF+ W P K ++ A+ Y + Y+ L + + + T +S PS P+++ + + S S V W P D H G I Y + Y A E+ I TS IL +L K+ Y+++VRA T VG G S+ K ++++ P P ++ E + T + +SW+ P LS K H I G+ ++Y+ +E+ + + NL A I GL P+ Y +AA G V P P + S N ++W P + + + ++++Y K++E K +F+ + + VT + + ++K+ + N E Y T D + P + +VGL +K+ ++RNGKI Y V+
Sbjct: 53 FVCQAVGEPKPRITW---------MKKGKKVSSQRFEVIEFDDGSGSVLRIQPLRTHRDEAIYECTATNSVGEINTSAKLTVLE-EDQIPHGFPTIDMGPQLKVVERTRTATMLCAASGNPDPEIYWFKDFLPVDISSSNGRIKQLRSGGTPIRGALQIENSEESDQGKYECVAVNSAGTRYSAPANLYVRVRRVPPRFSIPPTNHEVMPGGSVNLTCVAVGAPMPYVKWISGEVELTRED--------------EMPIGRNVLELT----------NIRQSANYT--CVAISS---LGMIETTAQITVKALPKMPT----SLTVTETTATSVTLTWDSGNPE----PVSYYVIQYRAKLSENGFQ---------EVDGVATTRYSIGGLSPFSEYEFRVMAVNNVGRGPSSSIVDTRTSEQAPSSPPLHVQARMLSSSTMLVQWEPPEEPN-GQIRGY---------RVYYSSDHDAPLSAWQKHNTDDSHFTTISGLATDITYSLRVLGFTSVGDGPPSDTLQIKTRQGVPAQPSDFDGEAELD----SRIMLSWLWPVQEPIISFELVYW------------EANNPTDKHRVTFDAAGS-----YAVDGLKPDTLYVFSLAARSEMGLGVFTQPIE----CRTAQSTPSAPPQEVHLLSLSSTSVEVRWVAPPTDSQH--GEIVGYSLAYQALTGEDQKRHQVSGIGPDITSYILEDLEKWTEYLVWVRAHTDVGPGPESSAAKVRTKEDVPGAP-PRKVEVEALNSTALRVSWK-PPLSVKQ--HGQIRGYQLVYSRLENGEPHGQPVILDVNLPEAQEAFIAGLLPETTYSVTVAAYTTKGDGARSKAKVATTTGAVPGK-----PTMMISTTIGNTALIQWQPPKEMVGEHMGYQLQY------------KRAEEEAFTIK--HFKKTDDHFTVTGLHKGAVYIFKLCAKNRAGNGEEYVKEISTPEDIPSSYPQNLS---VVGLTATSTKLAWDPPPLAERNGKIVKYVVM 952 HSP 3 Score: 129.798 bits (325), Expect = 5.592e-26 Identity = 218/964 (22.61%), Postives = 386/964 (40.04%), Query Frame = 1
Query: 277 NSQITFTENDEAP----KISLIIQSPNVLLFKSMILACSSTGHPVPSISWKINESPIEELKSPLKKLQNPPRIFSIKNYQNSVLVITQLIESDSNSVLICEAENNAGFD-SRQQQLKVISTETDIPSGFPVFQNNFFPIIKPYNSNVTLVCQAYGNPPPLIQWFKN-YELINESFTKIKILNDGNLLLVQVTREDKGIYHCQAQNTNGLRLSDPSTLDITSYPISPNSLIIERFASDNVEISWRSGLNDVTEQENFILHYR-EVPENITEKQIMSKFVYLTISEKKSIYKYNLKDLFPFTTYCIWMESENPLGVSPPTIALTVKTLPTSPQLSPRSITATSISNTAILVAWRPPERKFGKFKYYQIIYTNNDGFLPQHWRQFAVKDDNVMLTHLIASEL-YHIRVKIVNEIGHGPLSKTISIKTIAGTLSQCPDFKITEIFQSHIKLQWGTP--DPVKLFKLIQYNLLCWDVRLKIVNATAKSSTLFPILNHNLSMNEMEYVLYLKNEKEIKCRLSAINSDGKGM---PTEIQASTVNKGVNYQNLIHIDKIGSTYITFQWRPPSKFS-----FDYFLWIYQIFDSEKLDRAVKLPKIKINISDSASAENGWFVYNYTNAFSSSRYILGLRYLCRDSTDILREYVHRSDLVSTMKSVPSDSPKDLVVKEIDSNSALVSWKPLDQVHSNGIITHYEVRYYAPKKEESTERF----INVSET--SAILSNLKYFHYVIYVRAFTKVGGGSWSNPKNYYRQNLEEFP-IPTTIKGERKSETEINISWELPVLSEKNLAHAAIEGFIILYAPVESSPKWIKYTVQSKNLSAVIKGLEPDLRYQFQIAATNYAGFNGNFSEIVQEM--PKNFPNLNLKTVPDLRCSVQSSNRLKVEWSSPSIS---TDLLKFEIRYSGNLSYITEIGLKKSEFIDMESKSVNFETLVNRYDVTLENLQSNALYKIAVRA 3078
++++T E D+ P I + Q V ++ + C+++G+P P I W + P++ + S +++ ++ S L I ESD C A N+AG S L V P + P +V L C A G P P ++W EL E I N+L + R+ Y C A ++ G+ + + + + + P P SL + + +V ++W SG + +++ YR ++ EN ++ + + +Y++ L PF+ Y + + N +G P + + +T +P P + A +S++ +LV W PPE G+ + Y++ Y+++ W++ D + +A+++ Y +RV +G GP S T+ IKT G +Q DF S I L W P +P+ I + L+ W+ N T K F V LK + L+A + G G+ P E + + Q +H+ + ST + +W P S Y L YQ E R ++ I +I+ Y + + Y++ R TD+ + V T + VP P+ + V+ ++S + VSWKP V +G I Y++ Y + E + +N+ E + I L Y + V A+T G G+ S K P PT + T + I W+ P K + + G+ + Y E IK+ ++ + + GL Y F++ A N A GN E V+E+ P++ P+ + + + + S+ K+ W P ++ ++K+ + Y I+ + S N T +T+ LQ + Y I V+A
Sbjct: 120 SAKLTVLEEDQIPHGFPTIDMGPQLKVVERTRTATMLCAASGNPDPEIYWFKDFLPVD-ISSSNGRIK---QLRSGGTPIRGALQIENSEESDQGKYE-CVAVNSAGTRYSAPANLYVRVRRVPPRFSIPPTNHEVMP-----GGSVNLTCVAVGAPMPYVKWISGEVELTREDEMPI----GRNVLELTNIRQSAN-YTCVAISSLGM-IETTAQITVKALPKMPTSLTVTETTATSVTLTWDSGNPEPVSY--YVIQYRAKLSENGFQE-----------VDGVATTRYSIGGLSPFSEYEFRVMAVNNVGRGPSSSIVDTRTSEQAPSSPPLHVQARMLSSSTMLVQWEPPEEPNGQIRGYRVYYSSDHDAPLSAWQKHNTDDSHFTTISGLATDITYSLRVLGFTSVGDGPPSDTLQIKTRQGVPAQPSDFDGEAELDSRIMLSWLWPVQEPI-----ISFELVYWEAN----NPTDKHRVTFDAAGSYA-------VDGLKPDTLYVFSLAARSEMGLGVFTQPIECRTAQSTPSAPPQE-VHLLSLSSTSVEVRWVAPPTDSQHGEIVGYSL-AYQALTGEDQKRH-QVSGIGPDITS----------YILEDLEKWTEYLV----WVRAHTDVGPGPESSAAKVRTKEDVPGAPPRKVEVEALNSTALRVSWKPPLSVKQHGQIRGYQLVYSRLENGEPHGQPVILDVNLPEAQEAFIAGLLPETTYSVTVAAYTTKGDGARSKAK--VATTTGAVPGKPTMMISTTIGNTAL-IQWQPP----KEMVGEHM-GYQLQYKRAEEEAFTIKHFKKTDD-HFTVTGLHKGAVYIFKLCAKNRA---GNGEEYVKEISTPEDIPSSYPQNLSVVGLTATST---KLAWDPPPLAERNGKIVKYVVMYRD---------------INSPNNSTNVTTDTQ---MTVYGLQPDTTYDIRVQA 988 HSP 4 Score: 83.1889 bits (204), Expect = 7.584e-12 Identity = 129/597 (21.61%), Postives = 241/597 (40.37%), Query Frame = 1
Query: 1126 YNLKDLFPFTTYCIWMESENPLGVSPPTIALTVKTLPTSPQLSPRSITATSISNTAILVAW--RPPERKFGKFKYYQIIYTNNDGFLPQHWRQFAVKDDNVMLTHLIASEL-----YHIRVKIVNEIGHGPLSKTISIKTIAGTLSQCP-DFKITEIFQSHIKLQWGTPDPVKLFKLIQYNLLCWDVRLKIVNATAKSSTLFPILNHNLSMNEMEYVLYLKNEKEIKCRLSAINSDGKGMPTEIQASTVNKGVNYQNLIHIDK-IGSTYITFQWRPPSKFSFDYFLWIYQIFDSEKLDRAVKLPKIKINISDSASAENGWFVYNYTNAFSSSRYILGLRYLCRDSTDILREYVHRSDLVSTMKSVPSDSPKDLVVKEIDSNSALVSWKPLDQVHSNGIITHYEVRYYAPKKEESTERFINV-SETSAILSNLKY-FHYVIYVRAFTKVGGGSWSNPKNYYRQNLEEFP-IPTTIKG----ERKSETEINISWELPVLSEKNLAHAAIEGFIILYAPVESSPKWIKYTVQSKNLSAVIKGLEPDLRYQFQIAATNYAGFNGNFSEIVQEMPKNFPNLNLKTVPDLRCSVQSSNRLKVE 2868
Y + L P T Y + + + +G+ T + +T ++P P+ + S+S+T++ V W P + + G+ Y + Y G + ++ V +T I +L Y + V+ ++G GP S ++T P ++ + + +++ W P VK I+ L + ++ N + IL+ NL + ++ L E ++A + G G ++ + +T V + + I IG+T + QW+PP + ++ + Q +E+ +K +D + T + YI L ++ EYV +ST + +PS P++L V + + S ++W P NG I Y V Y + S NV ++T + L+ Y I V+AFT GGG S P R P +P+ + ++T + ++WE+P E + ++ ILY VQ +I L+PD Y F + + GN + +Q+ ++++T PDL + + + VE
Sbjct: 574 YAVDGLKPDTLYVFSLAARSEMGLGVFTQPIECRTAQSTPSAPPQEVHLLSLSSTSVEVRWVAPPTDSQHGEIVGYSLAYQALTG---EDQKRHQVSGIGPDITSYILEDLEKWTEYLVWVRAHTDVGPGPESSAAKVRTKEDVPGAPPRKVEVEALNSTALRVSWKPPLSVKQHGQIRGYQLVYS---RLENGEPHGQPV--ILDVNLPEAQEAFIAGLLPETTYSVTVAAYTTKGDGARSKAKVATTTGAVPGKPTMMISTTIGNTAL-IQWQPPKEMVGEHMGYQLQYKRAEEEAFTIK----HFKKTDDH--------FTVTGLHKGAVYIFKL--CAKNRAGNGEEYVKE---ISTPEDIPSSYPQNLSVVGLTATSTKLAWDPPPLAERNGKIVKYVVMY---RDINSPNNSTNVTTDTQMTVYGLQPDTTYDIRVQAFTSKGGGPIS-PSIQSRTMSTSMPDLPSVFTKNFGVKAVTKTSVLLTWEVP---ETYKSQVPVK---ILY-------NQQSVEVQGNLKRKLITQLQPDTDYSFVLMS------RGNSAGGLQQ------QVSIRTAPDLLTVKPAQHHIDVE 1115
BLAST of Protein tyrosine phosphatase receptor type D vs. TrEMBL
Match: A0A3P9B2Z8 (Protein tyrosine phosphatase receptor type Fa OS=Maylandia zebra OX=106582 PE=4 SV=1) HSP 1 Score: 726.472 bits (1874), Expect = 0.000e+0 Identity = 333/606 (54.95%), Postives = 441/606 (72.77%), Query Frame = 1
Query: 4006 SDSIKLRIGSQKSENISDRPSISICNLYQYVTDLKANDCTLLQAEFETLNTNLDDRFTWQRSNIDSNKSKNRYANVVAYDHTSVLLTPVDDVIGSDYINANYIDGYQRQNAYIATQGPLPDTTDDFWRMVWEQRSNCIVMMTRLEERSGIKCHQYWPNRGFICYGQMIVSHIDTFVLAYYTIRLFEIRHSKYSEKREIQHFQFTAWPDHGVPKLSTPLLMFIRRVRSIGKIESCPKIVHCSAGVGRTGAFIVVDAQLERIKQEKNIDVFNYVSKIRCQRNYMVQTQAQYQFILETLLEAVEDGNTEVMACNFHAHVTKLSQIGISGSNQLSGFEMEFSKLNSLASNRGRHGVMLADFVKAAGNQAVNMTKNRVRNIIPYEWNRVVLNAIRGIEGSDYINASYIDGYRDRRAYIAAQSPIPSTVEDFWRMLWDQHCGVVIVLNQPHE---DKSHIYWPINKSIRYQFFVVDPVVEYNMPNYILREFKVTDARDGEFRALRQFQFTQWPNHGCPKESESILDFIRQVHKTKEQFGHMEPMVIHCNTGSGRTGVFIALSIVLDRLQQESVVDMYQTVKLLHKQRIGLVQTEEQYEFCYMAVLDYLSNYE 5814
SD +++R + +++ + + P I++C+L ++ LKAND E+E+++ +FTW+ SN++ NK KNRYANV+AYDH+ V+LTPVD V GSDYINANYIDGY++QNAYIATQGPLP+T DFWRMVWEQR+ IVMMTRLEE+S +KC QYWP+RG YG + V+ +DT LA Y++R F + + SEKRE++ FQF AWPDHGVP+ TP L F+RR++S ++ P +VHCSAGVGRTG FIV+DA LER+K EK++D++ +V+ +R QRNYMVQT+ QY F+ E LLEA GNTEV A N +AH+ KL+Q ++ ++ E+EF KL + ++ R F+ A N N KNR+ NI+P+E RV L IRG+EGSDYINAS+IDGYR ++AY+A Q P+ T EDFWRMLW+ + +V++L + E +K H YWP +S RYQ+FVVDP+ EYNMP YILREFKVTDARDG+ R +RQFQFT WP G PK E +DFI QVHKTKEQFG P+ +HC+ G GRTGVFI LSIVL+R++ E VVD++QTVK L QR +VQTE+QY+ CY A L+YL +++
Sbjct: 1274 SDPVEMRRLNYQTQGMREHPPIAVCDLADHIERLKANDGLHFSQEYESIDPG--QQFTWEHSNLEVNKPKNRYANVIAYDHSRVILTPVDGVPGSDYINANYIDGYRKQNAYIATQGPLPETLSDFWRMVWEQRTCTIVMMTRLEEKSRVKCDQYWPSRGTETYGMIQVTMLDTLELATYSVRTFALYKNGSSEKREVRQFQFLAWPDHGVPEYPTPTLAFLRRIKSCNPQDAGPMVVHCSAGVGRTGCFIVIDAMLERMKHEKSVDIYGHVTCMRAQRNYMVQTEDQYIFVHEALLEAAVCGNTEVPARNLYAHIQKLTQ--VAAGEAVTAMELEFKKLANSKAHTSR-------FISA--NLPCNKFKNRLVNIMPFESTRVCLQPIRGVEGSDYINASFIDGYRQQKAYMATQGPLAETTEDFWRMLWEHNSTIVVMLTKLREMGREKCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDARDGQSRTIRQFQFTDWPEQGVPKTGEGFIDFIGQVHKTKEQFGQDGPITVHCSAGVGRTGVFITLSIVLERMRYEGVVDLFQTVKTLRTQRPAMVQTEDQYQLCYRAALEYLGSFD 1866 HSP 2 Score: 145.591 bits (366), Expect = 8.387e-31 Identity = 285/1262 (22.58%), Postives = 461/1262 (36.53%), Query Frame = 1
Query: 370 LACSSTGHPVPSISWKINESPIEELKSPLKKLQNPPRIFSIKNYQNSVLVITQLIESDSNSVLICEAENNAGFDSRQQQLKVISTETDIPSGFPVFQNNFFPIIKPYNSNVTLVCQAYGNPPPLIQWFKNYEL--INESFTKIKILNDGNLLLVQVTREDKGIYHCQAQNTNGLRLSDPSTLDI------TSYPISPNSLIIERFASDNVE----------ISWRSG------------------LNDVTEQENFI------LHYREVPENITEKQIMSKFVYLTISEKKS---IYKYNLKDLFPFTTYCIWME---SENPL--------------GVSP------------------PTIALTVKTLPTSPQLSPRSITATSISNTAILVAWRPPERKFGKFKYYQIIYTNNDGFLPQHWRQFAVKDDNVMLTHLIASEL-YHIRVKIVNEIGHGPLSKTISIKTIAGTLSQCPDFKITEIFQSHIKLQWGTP--DPVKLFKLIQYNLLCWDVRLKIVNATAKSSTLFPILNHNLSMNEMEYVLYLKNEKEIKCRLSAINSDGKGM---PTEIQASTVNKGVNYQNLIHIDKIGSTYITFQWRPPSKFS-----FDYFLWIYQIFDSEKLDRAVKLPKIKINISDSASAENGWFVYNYTNAFSSSRYILGLRYLCRDSTDILREYVHRSDLVSTMKSVPSDSPKDLVVKEIDSNSALVSWKPLDQVHSNGIITHYEVRYYAPKKEESTERF----INVSET--SAILSNLKYFHYVIYVRAFTKVGGGSWSNPKNYYRQNLEEFP-IPTTIKGERKSETEINISWELPVLSEKNLAHAAIEGFIILYAPVESSPKWIKYTVQSKNLSAVIKGLEPDLRYQFQIAATNYAGFNGNFSEIVQEM--PKNFPNLNLKTVPDLRCSVQSSNRLKVEWSSPSIS---TDLLKFEIRY--------SGNLSYITEI---GLKKSEFIDME------------SKSVNFETLVNRYDVTLENLQSNALYKIAVRAIYQNKELYESH-------------------RETTCDTMP-------------------------AVPNL--VKPPIIVGLDEEKSKVIIKLHRCSQRNGKISYYFVIVAAF-----QGNKNQQISFQEDTESYTFMELSVNTR-SNNAKGEYIAIMKD-INDIFKVSGKDHSSVLLGDGTHDENHLS--VNKKLEKNFNYRCFARVCLKYSNNSLCKSSPWSEPF--RISDLI 3606
C + G P P I+W +K K + + SVL I L ++ C A N+ G + +L V+ E IP GFP + T++C A GNP P I WFK++ I+ S +IK L G L + D+G Y C A N+ G R S P+ L + + I P + + S N+ + W SG L ++ + N+ L E IT K + LT++E + ++ + P + Y I SEN G+SP P+ + +T +P P + A +S++ +LV W PPE G+ + Y++ Y+++ W++ D + +A+++ Y +RV +G GP S T+ IKT G +Q DF S I L W P +P+ I + L+ W+ N T K F V LK + L+A + G G+ P E + + Q +H+ + ST + +W P S Y L YQ E R ++ I +I+ Y + + Y++ R TD+ + V T + VP P+ + V+ ++S + VSWKP V +G I Y++ Y + E + +N+ E + I L Y + V A+T G G+ S K P PT + T + I W+ P K + + G+ + Y E IK+ ++ + + GL Y F++ A N A GN E V+E+ P++ P+ + + + + S+ K+ W P ++ ++K+ + Y S N++ T++ GL+ D+ S S+ T+ V +N A+ K +V ++ E Y+S R+ P P+L VKP EE KV I L + YY V+V + + + QE ES L R SN+ YIA D + +IF + DE S NK L YRCF V +++ +SP+S+PF +IS +I
Sbjct: 30 FVCQAVGEPKPRITW---------MKKGKKVSSQRFEVIEFDDGSGSVLRIQPLRTHRDEAIYECTATNSVGEINTSAKLTVLE-EDQIPHGFPTIDMGPQLKVVERTRTATMLCAASGNPDPEIYWFKDFLPVDISSSNGRIKQLRSGALQIENSEESDQGKYECVAVNSAGTRYSAPANLYVRVRRVPPRFSIPPTNHEVMPGGSVNLTCVAVGAPMPYVKWISGEVELTREDEMPIGRNVLELTNIRQSANYTCVAISSLGMIETTAQITVKALPKMPTSLTVTETTATSVTLTWDSGNPEPVSYYVIQYRAKLSENGFQEVDGVATTRYSIGGLSPFSEYEFRVMAVNNVGRGPPSSIVDTRTSEQAPSSPPLHVQARMLSSSTMLVQWEPPEEPNGQIRGYRVYYSSDHDAPLSAWQKHNTDDSHFTTISGLATDITYSLRVLGFTSVGDGPPSDTLQIKTRQGVPAQPSDFDGEAELDSRIMLSWLWPVQEPI-----ISFELVYWEAN----NPTDKHRVTFDAAGSYA-------VDGLKPDTLYVFSLAARSEMGLGVFTQPIECRTAQSTPSAPPQE-VHLLSLSSTSVEVRWVAPPTDSQHGEIVGYSL-AYQALTGEDQKRH-QVSGIGPDITS----------YILEDLEKWTEYLV----WVRAHTDVGPGPESSAAKVRTKEDVPGAPPRKVEVEALNSTALRVSWKPPLSVKQHGQIRGYQLVYSRLENGEPHGQPVILDVNLPEAQEAFIAGLLPETTYSVTVAAYTTKGDGARSKAK--VATTTGAVPGKPTMMISTTIGNTAL-IQWQPP----KEMVGEHM-GYQLQYKRAEEEAFTIKHFKKTDD-HFTVTGLHKGAVYIFKLCAKNRA---GNGEEYVKEISTPEDIPSSYPQNLSVVGLTATST---KLAWDPPPLAERNGKIVKYVVMYRDINSPNNSTNVTTDTQMTVYGLQPDTTYDIRVQAFTSKGGGPISPSIQSRTMSTSMPVFTKNFGVKAVTKTSVLLTWEVPETYKSQVPVKILYNQQSVEVQGNLKRKLITQLQPDTDYSFVLMSRGNSAGGLQQQVSIRTAPDLLTVKPAQHHIDVEEGGKVTISLPKVPDAAAVRWYYIVVVPVTPVSLRRWENPEDMDIQELLESGADSSLQRRKRQSNDFLQPYIAAKLDTLPEIFTLG--------------DEKKYSGFYNKPLPGQQQYRCF--VLADLTDHETFAASPFSDPFTVKISGVI 1217
BLAST of Protein tyrosine phosphatase receptor type D vs. Ensembl Cavefish
Match: ptprfa (protein tyrosine phosphatase receptor type Fa [Source:ZFIN;Acc:ZDB-GENE-020107-2]) HSP 1 Score: 724.546 bits (1869), Expect = 0.000e+0 Identity = 331/606 (54.62%), Postives = 440/606 (72.61%), Query Frame = 1
Query: 4006 SDSIKLRIGSQKSENISDRPSISICNLYQYVTDLKANDCTLLQAEFETLNTNLDDRFTWQRSNIDSNKSKNRYANVVAYDHTSVLLTPVDDVIGSDYINANYIDGYQRQNAYIATQGPLPDTTDDFWRMVWEQRSNCIVMMTRLEERSGIKCHQYWPNRGFICYGQMIVSHIDTFVLAYYTIRLFEIRHSKYSEKREIQHFQFTAWPDHGVPKLSTPLLMFIRRVRSIGKIESCPKIVHCSAGVGRTGAFIVVDAQLERIKQEKNIDVFNYVSKIRCQRNYMVQTQAQYQFILETLLEAVEDGNTEVMACNFHAHVTKLSQIGISGSNQLSGFEMEFSKLNSLASNRGRHGVMLADFVKAAGNQAVNMTKNRVRNIIPYEWNRVVLNAIRGIEGSDYINASYIDGYRDRRAYIAAQSPIPSTVEDFWRMLWDQHCGVVIVLNQPHE---DKSHIYWPINKSIRYQFFVVDPVVEYNMPNYILREFKVTDARDGEFRALRQFQFTQWPNHGCPKESESILDFIRQVHKTKEQFGHMEPMVIHCNTGSGRTGVFIALSIVLDRLQQESVVDMYQTVKLLHKQRIGLVQTEEQYEFCYMAVLDYLSNYE 5814
SD +++R + +S+ + + P I +C+L ++ LKAND E+E+++ +FTW+ SN++ NK KNRYANV+AYDH+ V+LTPVD V GSDYINANY+DGY++QNAYI TQGPLP+T DFWRMVWEQR+N IVMMT+LEE+S +KC QYWP+RG YG + VS +DT LA Y++R F + + SEKRE++ FQF AWPDHGVP+ TP+L F+RRV++ ++ P +VHCSAGVGRTG FIV+DA LER+K EK++D++ +V+ +R QRNYMVQT+ QY FI E LLEA G+TEV A + + H+ KL+Q + + ++ E+EF KL + ++ R F+ A N N KNR+ NI+P+E RV L IRG+EGSDYINAS++DGYR ++AYIA Q P+ T EDFWRMLW+ + +V++L + E +K H YWP +S RYQ+FVVDP+ EYNMP YILREFKVTDARDG+ R +RQFQFT WP G PK E +DFI QVHKTKEQFG P+ +HC+ G GRTGVFI LSIVL+R++ E VVD++QTVK L QR +VQTE+QY+ CY A L+YL +++
Sbjct: 1317 SDPVEMRRLNYQSQGMREHPPIPVCDLADHIERLKANDGLRFSQEYESIDPG--QQFTWEHSNLEVNKPKNRYANVIAYDHSRVILTPVDGVPGSDYINANYVDGYRKQNAYIGTQGPLPETLSDFWRMVWEQRTNTIVMMTKLEEKSRVKCDQYWPSRGTETYGMIQVSMLDTVELATYSVRTFALYKNGSSEKREVRQFQFMAWPDHGVPEYPTPILAFLRRVKACNPPDAGPMVVHCSAGVGRTGCFIVIDAMLERMKHEKSVDIYGHVTCMRAQRNYMVQTEDQYVFIHEALLEAATCGHTEVPARSLYTHIQKLTQ--VPPGDTVTAMELEFKKLANSKAHTSR-------FISA--NLPCNKFKNRLVNIMPFESTRVCLQPIRGVEGSDYINASFLDGYRQQKAYIATQGPLAETTEDFWRMLWEHNSTIVVMLTKLREMGREKCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDARDGQSRTIRQFQFTDWPEQGVPKTGEGFIDFIGQVHKTKEQFGQDGPITVHCSAGVGRTGVFITLSIVLERMRYEGVVDLFQTVKTLRTQRPAMVQTEDQYQLCYRAALEYLGSFD 1909 HSP 2 Score: 152.91 bits (385), Expect = 2.020e-36 Identity = 228/996 (22.89%), Postives = 376/996 (37.75%), Query Frame = 1
Query: 370 LACSSTGHPVPSISWKINESPIEELKSPLKKLQNPPRIFSIKNYQNSVLVITQLIESDSNSVLICEAENNAGFDSRQQQLKVISTETDIPSGFPVFQNNFFPIIKPYNSNVTLVCQAYGNPPPLIQWFKNYEL--INESFTKIKILNDGNLLLVQVTREDKGIYHCQAQNTNGLRLSDPSTLDITSYPISPNSLIIERFASDNVEISWRSGLNDVTEQENFILHYREVPENITEKQIMSKFVYLTISEKKSIYK-----YNLKDLFPFTTYCIWMESENPLGVSPPTIALTVKTLPTSPQLSPRSITATSISNTAILVAW---RPPERKFGKFKYYQIIYTNNDGFLPQHWRQFAVKDDNVMLTHLIASELYHIRVKIVNEIGHGPLSKTISIKTIAGTLSQCP-DFKITEIFQSHIKLQWGTPDPVKLFKLIQYNLLCWDVRLKIVNATAKSSTLFPILN-HNLSMNEMEYVLYLKNEKEIKCRLSAINSDGKGMPTEIQASTVNKGVNYQNL-IHIDKIGSTYITFQWRPPSKFSFDYFLWIYQIFDSEKLDRAVKLPKIKINISDSASAENGWFVYNYTNAFSSSRYILGLRYLCRDSTDILREYVHRSDLVSTMKSVPSDSPKDLVVKEIDSNSALVSWKPLDQVHSNGIITHYEVRYYAPKKEESTE---RFINVSETSAILSNL-KYFHYVIYVRAFTKVGGGSWSNPKNYYRQNLEEFPIPTTIKGERKSETEINISWELPVLSEKNLAHAAIEGFIILYAPVESSPKWIKYTVQSKNL----SAVIKGLEPDLRYQFQIAATNYAGFNGNFSEIVQEMPKNFPNLNLKTVPDLRCSVQSSNRLKVEWSSP-SISTDLLKFEIRYSGNLSYITEIGLKKSEFIDMESKSVNFETLVNRYDVTLENLQSNALYKIAVRAIYQNKELYESHRETTCDTMPAVPNLVKPPIIVGLDEEKSKVIIKLHRCSQRNGKISYYFVIVAAFQGNKNQ 3291
C + G P P I+W +K K + + SVL I L ++ C A N+ G + +L V+ E IP GFP + T++C A GNP P I WFK++ IN S +IK L G L + D+G Y C A N+ G R S P+ L + + P RF+ + ++V + L V + + M+ V LT E+ I + N++ +T C+ + S LG+ T +TVK LP P S+ T + T++ + W P + +Y II +++GF V + L Y RV VN IG GP S T+ +T S P + + + + +QW P+ F +R V T + T + HN + + + L + R+ S G G P+++ +GV Q + T I W P + + IY DS P + +S + +Y +T A +R +GL + T +S PS P+++ + + S S VSW +G I Y + Y A E+ + I+ +S +L L K+ Y ++V+A T VG G S+ + P ++ + + T + +SW+ P L++K H + G+ ++Y+ VE+ + T+ L A I GL+ + Y +AA G V P P + S N ++W P + DLL + ++Y K+ E D F+ + + VT + + ++K++ R N E Y T D + P + +VGL +++ ++RNGKI Y V+ +N
Sbjct: 64 FVCQAVGEPKPRITW---------MKKGKKVSSQRFEVIEFDDGSGSVLRIQPLRTHRDEAIYECTATNSVGEINTSAKLIVLE-EDQIPHGFPTIDMGPQLKVVERTRTATMLCAASGNPDPEISWFKDFLPVDINGSNGRIKQLRSGALQIENSEESDQGKYECVAMNSAGTRYSAPANLYVRVRRVPP------RFSIPPIN-------HEVMPGGSLNLTCVAVGAPMPYVKWMTGEVELTKEEEMPIGRNVLELTNIRQSANYT--CVAISS---LGMIETTAQITVKALPRPPT----SLIVTETTATSVTLTWDSGNPEPVSYYVIQYRAII--SDNGFQEVD----GVASTRYSIGGLSPYSEYEFRVMAVNNIGRGPPSGTVETRTSEQAPSSPPLSVQARMLSATTMLVQWEPPEEPNGF-----------IRGYRVYYTHELHTPLSTWHKHNTDDSRLTTISGLVPDITYSLRVLGFTSVGDGPPSDVLQVKTQQGVPAQPTDFEAEAELDTRIMLTWLWPVQDQITKYELIYWEADSGDKTHVTFEPAGSYAV-ESLKPDT---LYKFTLA---ARSEMGLGVYTQPIE------------ARTAQSTPSAPPQEVHLLSLSSTSIQVSWVAPPAASRHGNIVRYSLAYQALSGEDQERHEVKDISADTSSYLLEGLEKWTEYQVWVKAHTDVGPGPESSSTRIRTKEDVPGAPPRRVEVDIINSTTLRVSWK-PPLAQKQ--HGQVRGYQVVYSRVENGEPRGQPTILDVALPEAQDAFITGLQAETSYSITVAAYTTKGDGARSKAKVVTTSGAVPGK-----PTMIISTTIGNTALIQWQPPKEMVGDLLGYTLQY------------KREE--DASFTVREFKRTDDHFTVTGLHKGATYIFKLSARNRAGNGEEYTKEVTTPEDVPGSYPQNLS---VVGLTTSSTELAWDPPPLAERNGKIVRYVVVYRDINSQQNH 966 HSP 3 Score: 138.272 bits (347), Expect = 4.942e-32 Identity = 217/963 (22.53%), Postives = 382/963 (39.67%), Query Frame = 1
Query: 265 LVLINSQIT--FTENDEAPKISLIIQSPNVLLFKSMILACSSTGHPVPSISWKINESPIEELKSPLKKLQNPPRIFSIKNYQNSVLVITQLIESDSNSVLICEAENNAGFD-SRQQQLKVISTETDIPSGFPVFQNNFFPIIKPYNSNVTLVCQAYGNPPPLIQWFKN-YELINESFTKIKILNDGNLLLVQVTREDKGIYHCQAQNTNGLRLSDPSTLDITSYPISPNSLIIERFASDNVEISWRSGLNDVTEQENFILHYREVPENITEKQIMSKFVYLTISEKKSIYKYNLKDLFPFTTYCIWMESENPLGVSPPTIALTVKTLPTSPQLSPRSITATSISNTAILVAWRPPERKFGKFKYYQIIYTNNDGFLPQHWRQFAVKDDNV-MLTHLIASELYHIRVKIVNEIGHGPLSKTISIKTIAGTLSQCPDFKITEIFQSHIKLQWGTPDPVKLFKLIQYNLLCWDVRLKIVNATAKSSTLF-PILNHNLSMNEMEYVLYLKNEKEIKCRLSAINSDGKGMPTE-IQASTVNKGVNY-QNLIHIDKIGSTYITFQWRPPSKFS----FDYFLWIYQIFDSEKLDRAVKLPKIKINISDSAS----AENGWFVYNYTNAFSSSRYILGLRYLCRDSTDILREYVHRSDLVSTMKSVPSDSPKDLVVKEIDSNSALVSWKPLDQVHSNGIITHYEVRYY-----APKKEESTERFINVSETSAILSNLKY-FHYVIYVRAFTKVGGGSWSNPKNYYRQNLEEFPIPTTIKGERKSETEINISWELPVLSEKNLAHAAIEGFIILYAPVESSPKWIKYTVQSKNLSAVIKGLEPDLRYQFQIAATNYAGFNGNFSEIV---QEMPKNFPNLNLKTVPDLRCSVQSSNRLKVEWSSPSISTDLLKFEIRYSGNLSYITEIGLKKSEFIDMESKSVNFETLVNRYDVTLENLQSNALYKIAVRA 3078
+VL QI F D P++ ++ ++ ++ + C+++G+P P ISW + P++ S + IK ++ L I ESD C A N+AG S L V P + P ++ L C A G P P ++W EL E I N+L + R+ Y C A ++ G+ + + + + + P P SLI+ + +V ++W SG + +++ YR I+S + + S +Y++ L P++ Y + + N +G PP+ + +T +P P S+ A +S T +LV W PPE G + Y++ YT+ W + D + ++ L+ Y +RV +G GP S + +KT G +Q DF+ + I L W P ++ K Y L+ W+ ++ K+ F P ++ V LK + K L+A + G G+ T+ I+A T + +H+ + ST I W P S + YQ E +R ++K +D++S W Y + + TD+ S + T + VP P+ + V I+S + VSWKP +G + Y+V Y P+ + + A ++ L+ Y I V A+T G G+ S K PT I T + I W+ P +L G+ + Y E + ++ ++ + + GL Y F+++A N AG +++ V +++P ++P NL V +++ ++ W P ++ K +RY + D+ S+ N + +T+ LQ++ Y I VRA
Sbjct: 135 IVLEEDQIPHGFPTIDMGPQLKVVERT------RTATMLCAASGNPDPEISWFKDFLPVDINGSNGR----------IKQLRSGALQIENSEESDQGKYE-CVAMNSAGTRYSAPANLYVRVRRVPPRFSIPPINHEVMP-----GGSLNLTCVAVGAPMPYVKWMTGEVELTKEEEMPI----GRNVLELTNIRQSAN-YTCVAISSLGM-IETTAQITVKALPRPPTSLIVTETTATSVTLTWDSGNPEPVSY--YVIQYRA---------IISDNGFQEVDGVAST-RYSIGGLSPYSEYEFRVMAVNNIGRGPPSGTVETRTSEQAPSSPPLSVQARMLSATTMLVQWEPPEEPNGFIRGYRVYYTHELHTPLSTWHKHNTDDSRLTTISGLVPDITYSLRVLGFTSVGDGPPSDVLQVKTQQGVPAQPTDFEAEAELDTRIMLTWLWPVQDQITK---YELIYWE-----ADSGDKTHVTFEPAGSYA--------VESLKPDTLYKFTLAARSEMGLGVYTQPIEARTAQSTPSAPPQEVHLLSLSSTSIQVSWVAPPAASRHGNIVRYSLAYQALSGEDQERH----EVKDISADTSSYLLEGLEKWTEY---------------QVWVKAHTDVGPGPESSSTRIRTKEDVPGAPPRRVEVDIINSTTLRVSWKPPLAQKQHGQVRGYQVVYSRVENGEPRGQPTILDVALPEAQDAFITGLQAETSYSITVAAYTTKGDGARSKAKVVTTSGAVPGK-PTMIISTTIGNTAL-IQWQPPKEMVGDLL-----GYTLQYKREEDASFTVREFKRTDD-HFTVTGLHKGATYIFKLSARNRAGNGEEYTKEVTTPEDVPGSYPQ-NLSVV------GLTTSSTELAWDPPPLAERNGKI-VRYV-------------VVYRDINSQQ-NHTNTTAQTRMTINGLQADTTYDIRVRA 992 HSP 4 Score: 88.9669 bits (219), Expect = 4.971e-17 Identity = 132/584 (22.60%), Postives = 231/584 (39.55%), Query Frame = 1
Query: 1126 YNLKDLFPFTTYCIWMESENPLGVSPPTIALTVKTLPTSPQLSPRSITATSISNTAILVAW--RPPERKFGKFKYYQIIYTNNDGFLPQHWRQFAVKD-----DNVMLTHLIASELYHIRVKIVNEIGHGPLSKTISIKTIAGTLSQCPDFKITEIFQSH-IKLQWGTPDPVKLFKLIQYNLLCWDVRLKIVNATAKSSTLFPILNHNLSMNEMEYVLYLKNEKEIKCRLSAINSDGKGMPTEIQASTVNKGV-NYQNLIHIDKIGSTYITFQWRPPSKFSFDYFLWIYQIFDSEKLDRAVKLPKIKINISDSASAENGWFVYNYTNAFSSSRYILGLRYLCRDSTDILREYVHRSDLVSTMKSVPSDSPKDLVVKEIDSNSALVSWKPLDQVHSNGIITHYEVRYYAPKKEESTERFIN-VSETSAILSNLKY-FHYVIYVRAFTKVGGG--SWSNPKNYYRQNLEEFPIPTTIKGERKSETEINISWELPVLSEKNLAHAAIEGFIILYAPVESSPKWIKYTVQSKNLSAVIKGLEPDLRYQFQIAATNYAGFNGNFSEIVQEMPKNFPNLNLKTVPDLRCS 2838
Y ++ L P T Y + + + +G+ T + +T ++P P+ + S+S+T+I V+W P + G Y + Y G + + VKD + +L L Y + VK ++G GP S + I+T P +I S +++ W P K ++ + + ++ N + IL+ L + ++ L+ E ++A + G G ++ + T + V +I IG+T + QW+PP + D + Q E V+ + +D + T + YI L R+ EY V+T + VP P++L V + ++S ++W P NG I Y V Y + S + N ++T ++ L+ Y I VRAFT GGG S S ++ EF +K KS + ++WE+P + + F ILY VQ +I L+PD Y F + + GN + +Q+ ++++T PDL S
Sbjct: 578 YAVESLKPDTLYKFTLAARSEMGLGVYTQPIEARTAQSTPSAPPQEVHLLSLSSTSIQVSWVAPPAASRHGNIVRYSLAYQALSG---EDQERHEVKDISADTSSYLLEGLEKWTEYQVWVKAHTDVGPGPESSSTRIRTKEDVPGAPPRRVEVDIINSTTLRVSWKPPLAQKQHGQVRGYQVVYS---RVENGEPRGQPT--ILDVALPEAQDAFITGLQAETSYSITVAAYTTKGDGARSKAKVVTTSGAVPGKPTMIISTTIGNTAL-IQWQPPKEMVGDLLGYTLQYKREEDASFTVR----EFKRTDDH--------FTVTGLHKGATYIFKLS--ARNRAGNGEEYTKE---VTTPEDVPGSYPQNLSVVGLTTSSTELAWDPPPLAERNGKIVRYVVVY---RDINSQQNHTNTTAQTRMTINGLQADTTYDIRVRAFTSKGGGPISPSIQSRTMATSMPEFTKNFGVKAVMKS--SVLLTWEVPETYKSQVP------FKILY-------NQQSVEVQGDLKRKLITRLQPDTDYSFVLMS------RGNSAGGLQQ------QVSIRTAPDLLTS 1105
BLAST of Protein tyrosine phosphatase receptor type D vs. Ensembl Cavefish
Match: ptprfa (protein tyrosine phosphatase receptor type Fa [Source:ZFIN;Acc:ZDB-GENE-020107-2]) HSP 1 Score: 716.842 bits (1849), Expect = 0.000e+0 Identity = 327/591 (55.33%), Postives = 430/591 (72.76%), Query Frame = 1
Query: 4051 ISDRPSISICNLYQYVTDLKANDCTLLQAEFETLNTNLDDRFTWQRSNIDSNKSKNRYANVVAYDHTSVLLTPVDDVIGSDYINANYIDGYQRQNAYIATQGPLPDTTDDFWRMVWEQRSNCIVMMTRLEERSGIKCHQYWPNRGFICYGQMIVSHIDTFVLAYYTIRLFEIRHSKYSEKREIQHFQFTAWPDHGVPKLSTPLLMFIRRVRSIGKIESCPKIVHCSAGVGRTGAFIVVDAQLERIKQEKNIDVFNYVSKIRCQRNYMVQTQAQYQFILETLLEAVEDGNTEVMACNFHAHVTKLSQIGISGSNQLSGFEMEFSKLNSLASNRGRHGVMLADFVKAAGNQAVNMTKNRVRNIIPYEWNRVVLNAIRGIEGSDYINASYIDGYRDRRAYIAAQSPIPSTVEDFWRMLWDQHCGVVIVLNQPHE---DKSHIYWPINKSIRYQFFVVDPVVEYNMPNYILREFKVTDARDGEFRALRQFQFTQWPNHGCPKESESILDFIRQVHKTKEQFGHMEPMVIHCNTGSGRTGVFIALSIVLDRLQQESVVDMYQTVKLLHKQRIGLVQTEEQYEFCYMAVLDYLSNYE 5814
+ + P I +C+L ++ LKAND E+E+++ +FTW+ SN++ NK KNRYANV+AYDH+ V+LTPVD V GSDYINANY+DGY++QNAYI TQGPLP+T DFWRMVWEQR+N IVMMT+LEE+S +KC QYWP+RG YG + VS +DT LA Y++R F + + SEKRE++ FQF AWPDHGVP+ TP+L F+RRV++ ++ P +VHCSAGVGRTG FIV+DA LER+K EK++D++ +V+ +R QRNYMVQT+ QY FI E LLEA G+TEV A + + H+ KL+Q + + ++ E+EF KL + ++ R F+ A N N KNR+ NI+P+E RV L IRG+EGSDYINAS++DGYR ++AYIA Q P+ T EDFWRMLW+ + +V++L + E +K H YWP +S RYQ+FVVDP+ EYNMP YILREFKVTDARDG+ R +RQFQFT WP G PK E +DFI QVHKTKEQFG P+ +HC+ G GRTGVFI LSIVL+R++ E VVD++QTVK L QR +VQTE+QY+ CY A L+YL +++
Sbjct: 1265 MREHPPIPVCDLADHIERLKANDGLRFSQEYESIDPG--QQFTWEHSNLEVNKPKNRYANVIAYDHSRVILTPVDGVPGSDYINANYVDGYRKQNAYIGTQGPLPETLSDFWRMVWEQRTNTIVMMTKLEEKSRVKCDQYWPSRGTETYGMIQVSMLDTVELATYSVRTFALYKNGSSEKREVRQFQFMAWPDHGVPEYPTPILAFLRRVKACNPPDAGPMVVHCSAGVGRTGCFIVIDAMLERMKHEKSVDIYGHVTCMRAQRNYMVQTEDQYVFIHEALLEAATCGHTEVPARSLYTHIQKLTQ--VPPGDTVTAMELEFKKLANSKAHTSR-------FISA--NLPCNKFKNRLVNIMPFESTRVCLQPIRGVEGSDYINASFLDGYRQQKAYIATQGPLAETTEDFWRMLWEHNSTIVVMLTKLREMGREKCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDARDGQSRTIRQFQFTDWPEQGVPKTGEGFIDFIGQVHKTKEQFGQDGPITVHCSAGVGRTGVFITLSIVLERMRYEGVVDLFQTVKTLRTQRPAMVQTEDQYQLCYRAALEYLGSFD 1842 HSP 2 Score: 145.591 bits (366), Expect = 3.346e-34 Identity = 220/959 (22.94%), Postives = 365/959 (38.06%), Query Frame = 1
Query: 481 IFSIKNYQNSVLVITQLIESDSNSVLICEAENNAGFDSRQQQLKVISTETDIPSGFPVFQNNFFPIIKPYNSNVTLVCQAYGNPPPLIQWFKNYEL--INESFTKIKILNDGNLLLVQVTREDKGIYHCQAQNTNGLRLSDPSTLDITSYPISPNSLIIERFASDNVEISWRSGLNDVTEQENFILHYREVPENITEKQIMSKFVYLTISEKKSIYK-----YNLKDLFPFTTYCIWMESENPLGVSPPTIALTVKTLPTSPQLSPRSITATSISNTAILVAW---RPPERKFGKFKYYQIIYTNNDGFLPQHWRQFAVKDDNVMLTHLIASELYHIRVKIVNEIGHGPLSKTISIKTIAGTLSQCP-DFKITEIFQSHIKLQWGTPDPVKLFKLIQYNLLCWDVRLKIVNATAKSSTLFPILN-HNLSMNEMEYVLYLKNEKEIKCRLSAINSDGKGMPTEIQASTVNKGVNYQNL-IHIDKIGSTYITFQWRPPSKFSFDYFLWIYQIFDSEKLDRAVKLPKIKINISDSASAENGWFVYNYTNAFSSSRYILGLRYLCRDSTDILREYVHRSDLVSTMKSVPSDSPKDLVVKEIDSNSALVSWKPLDQVHSNGIITHYEVRYYAPKKEESTE---RFINVSETSAILSNL-KYFHYVIYVRAFTKVGGGSWSNPKNYYRQNLEEFPIPTTIKGERKSETEINISWELPVLSEKNLAHAAIEGFIILYAPVESSPKWIKYTVQSKNL----SAVIKGLEPDLRYQFQIAATNYAGFNGNFSEIVQEMPKNFPNLNLKTVPDLRCSVQSSNRLKVEWSSP-SISTDLLKFEIRYSGNLSYITEIGLKKSEFIDMESKSVNFETLVNRYDVTLENLQSNALYKIAVRAIYQNKELYESHRETTCDTMPAVPNLVKPPIIVGLDEEKSKVIIKLHRCSQRNGKISYYFVIVAAFQGNKNQ 3291
+ + SVL I L ++ C A N+ G + +L V+ E IP GFP + T++C A GNP P I WFK++ IN S +IK L G L + D+G Y C A N+ G R S P+ L + + P RF+ + ++V + L V + + M+ V LT E+ I + N++ +T C+ + S LG+ T +TVK LP P S+ T + T++ + W P + +Y II +++GF V + L Y RV VN IG GP S T+ +T S P + + + + +QW P+ F +R V T + T + HN + + + L + R+ S G G P+++ +GV Q + T I W P + + IY DS P + +S + +Y +T A +R +GL + T +S PS P+++ + + S S VSW +G I Y + Y A E+ + I+ +S +L L K+ Y ++V+A T VG G S+ + P ++ + + T + +SW+ P L++K H + G+ ++Y+ VE+ + T+ L A I GL+ + Y +AA G V P P + S N ++W P + DLL + ++Y K+ E D F+ + + VT + + ++K++ R N E Y T D + P + +VGL +++ ++RNGKI Y V+ +N
Sbjct: 14 VIEFDDGSGSVLRIQPLRTHRDEAIYECTATNSVGEINTSAKLIVLE-EDQIPHGFPTIDMGPQLKVVERTRTATMLCAASGNPDPEISWFKDFLPVDINGSNGRIKQLRSGALQIENSEESDQGKYECVAMNSAGTRYSAPANLYVRVRRVPP------RFSIPPIN-------HEVMPGGSLNLTCVAVGAPMPYVKWMTGEVELTKEEEMPIGRNVLELTNIRQSANYT--CVAISS---LGMIETTAQITVKALPRPPT----SLIVTETTATSVTLTWDSGNPEPVSYYVIQYRAII--SDNGFQEVD----GVASTRYSIGGLSPYSEYEFRVMAVNNIGRGPPSGTVETRTSEQAPSSPPLSVQARMLSATTMLVQWEPPEEPNGF-----------IRGYRVYYTHELHTPLSTWHKHNTDDSRLTTISGLVPDITYSLRVLGFTSVGDGPPSDVLQVKTQQGVPAQPTDFEAEAELDTRIMLTWLWPVQDQITKYELIYWEADSGDKTHVTFEPAGSYAV-ESLKPDT---LYKFTLA---ARSEMGLGVYTQPIE------------ARTAQSTPSAPPQEVHLLSLSSTSIQVSWVAPPAASRHGNIVRYSLAYQALSGEDQERHEVKDISADTSSYLLEGLEKWTEYQVWVKAHTDVGPGPESSSTRIRTKEDVPGAPPRRVEVDIINSTTLRVSWK-PPLAQKQ--HGQVRGYQVVYSRVENGEPRGQPTILDVALPEAQDAFITGLQAETSYSITVAAYTTKGDGARSKAKVVTTSGAVPGK-----PTMIISTTIGNTALIQWQPPKEMVGDLLGYTLQY------------KREE--DASFTVREFKRTDDHFTVTGLHKGATYIFKLSARNRAGNGEEYTKEVTTPEDVPGSYPQNLS---VVGLTTSSTELAWDPPPLAERNGKIVRYVVVYRDINSQQNH 888 HSP 3 Score: 137.887 bits (346), Expect = 6.634e-32 Identity = 217/963 (22.53%), Postives = 382/963 (39.67%), Query Frame = 1
Query: 265 LVLINSQIT--FTENDEAPKISLIIQSPNVLLFKSMILACSSTGHPVPSISWKINESPIEELKSPLKKLQNPPRIFSIKNYQNSVLVITQLIESDSNSVLICEAENNAGFD-SRQQQLKVISTETDIPSGFPVFQNNFFPIIKPYNSNVTLVCQAYGNPPPLIQWFKN-YELINESFTKIKILNDGNLLLVQVTREDKGIYHCQAQNTNGLRLSDPSTLDITSYPISPNSLIIERFASDNVEISWRSGLNDVTEQENFILHYREVPENITEKQIMSKFVYLTISEKKSIYKYNLKDLFPFTTYCIWMESENPLGVSPPTIALTVKTLPTSPQLSPRSITATSISNTAILVAWRPPERKFGKFKYYQIIYTNNDGFLPQHWRQFAVKDDNV-MLTHLIASELYHIRVKIVNEIGHGPLSKTISIKTIAGTLSQCPDFKITEIFQSHIKLQWGTPDPVKLFKLIQYNLLCWDVRLKIVNATAKSSTLF-PILNHNLSMNEMEYVLYLKNEKEIKCRLSAINSDGKGMPTE-IQASTVNKGVNY-QNLIHIDKIGSTYITFQWRPPSKFS----FDYFLWIYQIFDSEKLDRAVKLPKIKINISDSAS----AENGWFVYNYTNAFSSSRYILGLRYLCRDSTDILREYVHRSDLVSTMKSVPSDSPKDLVVKEIDSNSALVSWKPLDQVHSNGIITHYEVRYY-----APKKEESTERFINVSETSAILSNLKY-FHYVIYVRAFTKVGGGSWSNPKNYYRQNLEEFPIPTTIKGERKSETEINISWELPVLSEKNLAHAAIEGFIILYAPVESSPKWIKYTVQSKNLSAVIKGLEPDLRYQFQIAATNYAGFNGNFSEIV---QEMPKNFPNLNLKTVPDLRCSVQSSNRLKVEWSSPSISTDLLKFEIRYSGNLSYITEIGLKKSEFIDMESKSVNFETLVNRYDVTLENLQSNALYKIAVRA 3078
+VL QI F D P++ ++ ++ ++ + C+++G+P P ISW + P++ S + IK ++ L I ESD C A N+AG S L V P + P ++ L C A G P P ++W EL E I N+L + R+ Y C A ++ G+ + + + + + P P SLI+ + +V ++W SG + +++ YR I+S + + S +Y++ L P++ Y + + N +G PP+ + +T +P P S+ A +S T +LV W PPE G + Y++ YT+ W + D + ++ L+ Y +RV +G GP S + +KT G +Q DF+ + I L W P ++ K Y L+ W+ ++ K+ F P ++ V LK + K L+A + G G+ T+ I+A T + +H+ + ST I W P S + YQ E +R ++K +D++S W Y + + TD+ S + T + VP P+ + V I+S + VSWKP +G + Y+V Y P+ + + A ++ L+ Y I V A+T G G+ S K PT I T + I W+ P +L G+ + Y E + ++ ++ + + GL Y F+++A N AG +++ V +++P ++P NL V +++ ++ W P ++ K +RY + D+ S+ N + +T+ LQ++ Y I VRA
Sbjct: 57 IVLEEDQIPHGFPTIDMGPQLKVVERT------RTATMLCAASGNPDPEISWFKDFLPVDINGSNGR----------IKQLRSGALQIENSEESDQGKYE-CVAMNSAGTRYSAPANLYVRVRRVPPRFSIPPINHEVMP-----GGSLNLTCVAVGAPMPYVKWMTGEVELTKEEEMPI----GRNVLELTNIRQSAN-YTCVAISSLGM-IETTAQITVKALPRPPTSLIVTETTATSVTLTWDSGNPEPVSY--YVIQYRA---------IISDNGFQEVDGVAST-RYSIGGLSPYSEYEFRVMAVNNIGRGPPSGTVETRTSEQAPSSPPLSVQARMLSATTMLVQWEPPEEPNGFIRGYRVYYTHELHTPLSTWHKHNTDDSRLTTISGLVPDITYSLRVLGFTSVGDGPPSDVLQVKTQQGVPAQPTDFEAEAELDTRIMLTWLWPVQDQITK---YELIYWE-----ADSGDKTHVTFEPAGSYA--------VESLKPDTLYKFTLAARSEMGLGVYTQPIEARTAQSTPSAPPQEVHLLSLSSTSIQVSWVAPPAASRHGNIVRYSLAYQALSGEDQERH----EVKDISADTSSYLLEGLEKWTEY---------------QVWVKAHTDVGPGPESSSTRIRTKEDVPGAPPRRVEVDIINSTTLRVSWKPPLAQKQHGQVRGYQVVYSRVENGEPRGQPTILDVALPEAQDAFITGLQAETSYSITVAAYTTKGDGARSKAKVVTTSGAVPGK-PTMIISTTIGNTAL-IQWQPPKEMVGDLL-----GYTLQYKREEDASFTVREFKRTDD-HFTVTGLHKGATYIFKLSARNRAGNGEEYTKEVTTPEDVPGSYPQ-NLSVV------GLTTSSTELAWDPPPLAERNGKI-VRYV-------------VVYRDINSQQ-NHTNTTAQTRMTINGLQADTTYDIRVRA 914 HSP 4 Score: 88.5817 bits (218), Expect = 6.080e-17 Identity = 132/584 (22.60%), Postives = 231/584 (39.55%), Query Frame = 1
Query: 1126 YNLKDLFPFTTYCIWMESENPLGVSPPTIALTVKTLPTSPQLSPRSITATSISNTAILVAW--RPPERKFGKFKYYQIIYTNNDGFLPQHWRQFAVKD-----DNVMLTHLIASELYHIRVKIVNEIGHGPLSKTISIKTIAGTLSQCPDFKITEIFQSH-IKLQWGTPDPVKLFKLIQYNLLCWDVRLKIVNATAKSSTLFPILNHNLSMNEMEYVLYLKNEKEIKCRLSAINSDGKGMPTEIQASTVNKGV-NYQNLIHIDKIGSTYITFQWRPPSKFSFDYFLWIYQIFDSEKLDRAVKLPKIKINISDSASAENGWFVYNYTNAFSSSRYILGLRYLCRDSTDILREYVHRSDLVSTMKSVPSDSPKDLVVKEIDSNSALVSWKPLDQVHSNGIITHYEVRYYAPKKEESTERFIN-VSETSAILSNLKY-FHYVIYVRAFTKVGGG--SWSNPKNYYRQNLEEFPIPTTIKGERKSETEINISWELPVLSEKNLAHAAIEGFIILYAPVESSPKWIKYTVQSKNLSAVIKGLEPDLRYQFQIAATNYAGFNGNFSEIVQEMPKNFPNLNLKTVPDLRCS 2838
Y ++ L P T Y + + + +G+ T + +T ++P P+ + S+S+T+I V+W P + G Y + Y G + + VKD + +L L Y + VK ++G GP S + I+T P +I S +++ W P K ++ + + ++ N + IL+ L + ++ L+ E ++A + G G ++ + T + V +I IG+T + QW+PP + D + Q E V+ + +D + T + YI L R+ EY V+T + VP P++L V + ++S ++W P NG I Y V Y + S + N ++T ++ L+ Y I VRAFT GGG S S ++ EF +K KS + ++WE+P + + F ILY VQ +I L+PD Y F + + GN + +Q+ ++++T PDL S
Sbjct: 500 YAVESLKPDTLYKFTLAARSEMGLGVYTQPIEARTAQSTPSAPPQEVHLLSLSSTSIQVSWVAPPAASRHGNIVRYSLAYQALSG---EDQERHEVKDISADTSSYLLEGLEKWTEYQVWVKAHTDVGPGPESSSTRIRTKEDVPGAPPRRVEVDIINSTTLRVSWKPPLAQKQHGQVRGYQVVYS---RVENGEPRGQPT--ILDVALPEAQDAFITGLQAETSYSITVAAYTTKGDGARSKAKVVTTSGAVPGKPTMIISTTIGNTAL-IQWQPPKEMVGDLLGYTLQYKREEDASFTVR----EFKRTDDH--------FTVTGLHKGATYIFKLS--ARNRAGNGEEYTKE---VTTPEDVPGSYPQNLSVVGLTTSSTELAWDPPPLAERNGKIVRYVVVY---RDINSQQNHTNTTAQTRMTINGLQADTTYDIRVRAFTSKGGGPISPSIQSRTMATSMPEFTKNFGVKAVMKS--SVLLTWEVPETYKSQVP------FKILY-------NQQSVEVQGDLKRKLITRLQPDTDYSFVLMS------RGNSAGGLQQ------QVSIRTAPDLLTS 1027
BLAST of Protein tyrosine phosphatase receptor type D vs. Ensembl Cavefish
Match: ptprfa (protein tyrosine phosphatase receptor type Fa [Source:ZFIN;Acc:ZDB-GENE-020107-2]) HSP 1 Score: 716.842 bits (1849), Expect = 0.000e+0 Identity = 327/591 (55.33%), Postives = 430/591 (72.76%), Query Frame = 1
Query: 4051 ISDRPSISICNLYQYVTDLKANDCTLLQAEFETLNTNLDDRFTWQRSNIDSNKSKNRYANVVAYDHTSVLLTPVDDVIGSDYINANYIDGYQRQNAYIATQGPLPDTTDDFWRMVWEQRSNCIVMMTRLEERSGIKCHQYWPNRGFICYGQMIVSHIDTFVLAYYTIRLFEIRHSKYSEKREIQHFQFTAWPDHGVPKLSTPLLMFIRRVRSIGKIESCPKIVHCSAGVGRTGAFIVVDAQLERIKQEKNIDVFNYVSKIRCQRNYMVQTQAQYQFILETLLEAVEDGNTEVMACNFHAHVTKLSQIGISGSNQLSGFEMEFSKLNSLASNRGRHGVMLADFVKAAGNQAVNMTKNRVRNIIPYEWNRVVLNAIRGIEGSDYINASYIDGYRDRRAYIAAQSPIPSTVEDFWRMLWDQHCGVVIVLNQPHE---DKSHIYWPINKSIRYQFFVVDPVVEYNMPNYILREFKVTDARDGEFRALRQFQFTQWPNHGCPKESESILDFIRQVHKTKEQFGHMEPMVIHCNTGSGRTGVFIALSIVLDRLQQESVVDMYQTVKLLHKQRIGLVQTEEQYEFCYMAVLDYLSNYE 5814
+ + P I +C+L ++ LKAND E+E+++ +FTW+ SN++ NK KNRYANV+AYDH+ V+LTPVD V GSDYINANY+DGY++QNAYI TQGPLP+T DFWRMVWEQR+N IVMMT+LEE+S +KC QYWP+RG YG + VS +DT LA Y++R F + + SEKRE++ FQF AWPDHGVP+ TP+L F+RRV++ ++ P +VHCSAGVGRTG FIV+DA LER+K EK++D++ +V+ +R QRNYMVQT+ QY FI E LLEA G+TEV A + + H+ KL+Q + + ++ E+EF KL + ++ R F+ A N N KNR+ NI+P+E RV L IRG+EGSDYINAS++DGYR ++AYIA Q P+ T EDFWRMLW+ + +V++L + E +K H YWP +S RYQ+FVVDP+ EYNMP YILREFKVTDARDG+ R +RQFQFT WP G PK E +DFI QVHKTKEQFG P+ +HC+ G GRTGVFI LSIVL+R++ E VVD++QTVK L QR +VQTE+QY+ CY A L+YL +++
Sbjct: 1339 MREHPPIPVCDLADHIERLKANDGLRFSQEYESIDPG--QQFTWEHSNLEVNKPKNRYANVIAYDHSRVILTPVDGVPGSDYINANYVDGYRKQNAYIGTQGPLPETLSDFWRMVWEQRTNTIVMMTKLEEKSRVKCDQYWPSRGTETYGMIQVSMLDTVELATYSVRTFALYKNGSSEKREVRQFQFMAWPDHGVPEYPTPILAFLRRVKACNPPDAGPMVVHCSAGVGRTGCFIVIDAMLERMKHEKSVDIYGHVTCMRAQRNYMVQTEDQYVFIHEALLEAATCGHTEVPARSLYTHIQKLTQ--VPPGDTVTAMELEFKKLANSKAHTSR-------FISA--NLPCNKFKNRLVNIMPFESTRVCLQPIRGVEGSDYINASFLDGYRQQKAYIATQGPLAETTEDFWRMLWEHNSTIVVMLTKLREMGREKCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDARDGQSRTIRQFQFTDWPEQGVPKTGEGFIDFIGQVHKTKEQFGQDGPITVHCSAGVGRTGVFITLSIVLERMRYEGVVDLFQTVKTLRTQRPAMVQTEDQYQLCYRAALEYLGSFD 1916 HSP 2 Score: 152.91 bits (385), Expect = 2.202e-36 Identity = 228/996 (22.89%), Postives = 376/996 (37.75%), Query Frame = 1
Query: 370 LACSSTGHPVPSISWKINESPIEELKSPLKKLQNPPRIFSIKNYQNSVLVITQLIESDSNSVLICEAENNAGFDSRQQQLKVISTETDIPSGFPVFQNNFFPIIKPYNSNVTLVCQAYGNPPPLIQWFKNYEL--INESFTKIKILNDGNLLLVQVTREDKGIYHCQAQNTNGLRLSDPSTLDITSYPISPNSLIIERFASDNVEISWRSGLNDVTEQENFILHYREVPENITEKQIMSKFVYLTISEKKSIYK-----YNLKDLFPFTTYCIWMESENPLGVSPPTIALTVKTLPTSPQLSPRSITATSISNTAILVAW---RPPERKFGKFKYYQIIYTNNDGFLPQHWRQFAVKDDNVMLTHLIASELYHIRVKIVNEIGHGPLSKTISIKTIAGTLSQCP-DFKITEIFQSHIKLQWGTPDPVKLFKLIQYNLLCWDVRLKIVNATAKSSTLFPILN-HNLSMNEMEYVLYLKNEKEIKCRLSAINSDGKGMPTEIQASTVNKGVNYQNL-IHIDKIGSTYITFQWRPPSKFSFDYFLWIYQIFDSEKLDRAVKLPKIKINISDSASAENGWFVYNYTNAFSSSRYILGLRYLCRDSTDILREYVHRSDLVSTMKSVPSDSPKDLVVKEIDSNSALVSWKPLDQVHSNGIITHYEVRYYAPKKEESTE---RFINVSETSAILSNL-KYFHYVIYVRAFTKVGGGSWSNPKNYYRQNLEEFPIPTTIKGERKSETEINISWELPVLSEKNLAHAAIEGFIILYAPVESSPKWIKYTVQSKNL----SAVIKGLEPDLRYQFQIAATNYAGFNGNFSEIVQEMPKNFPNLNLKTVPDLRCSVQSSNRLKVEWSSP-SISTDLLKFEIRYSGNLSYITEIGLKKSEFIDMESKSVNFETLVNRYDVTLENLQSNALYKIAVRAIYQNKELYESHRETTCDTMPAVPNLVKPPIIVGLDEEKSKVIIKLHRCSQRNGKISYYFVIVAAFQGNKNQ 3291
C + G P P I+W +K K + + SVL I L ++ C A N+ G + +L V+ E IP GFP + T++C A GNP P I WFK++ IN S +IK L G L + D+G Y C A N+ G R S P+ L + + P RF+ + ++V + L V + + M+ V LT E+ I + N++ +T C+ + S LG+ T +TVK LP P S+ T + T++ + W P + +Y II +++GF V + L Y RV VN IG GP S T+ +T S P + + + + +QW P+ F +R V T + T + HN + + + L + R+ S G G P+++ +GV Q + T I W P + + IY DS P + +S + +Y +T A +R +GL + T +S PS P+++ + + S S VSW +G I Y + Y A E+ + I+ +S +L L K+ Y ++V+A T VG G S+ + P ++ + + T + +SW+ P L++K H + G+ ++Y+ VE+ + T+ L A I GL+ + Y +AA G V P P + S N ++W P + DLL + ++Y K+ E D F+ + + VT + + ++K++ R N E Y T D + P + +VGL +++ ++RNGKI Y V+ +N
Sbjct: 64 FVCQAVGEPKPRITW---------MKKGKKVSSQRFEVIEFDDGSGSVLRIQPLRTHRDEAIYECTATNSVGEINTSAKLIVLE-EDQIPHGFPTIDMGPQLKVVERTRTATMLCAASGNPDPEISWFKDFLPVDINGSNGRIKQLRSGALQIENSEESDQGKYECVAMNSAGTRYSAPANLYVRVRRVPP------RFSIPPIN-------HEVMPGGSLNLTCVAVGAPMPYVKWMTGEVELTKEEEMPIGRNVLELTNIRQSANYT--CVAISS---LGMIETTAQITVKALPRPPT----SLIVTETTATSVTLTWDSGNPEPVSYYVIQYRAII--SDNGFQEVD----GVASTRYSIGGLSPYSEYEFRVMAVNNIGRGPPSGTVETRTSEQAPSSPPLSVQARMLSATTMLVQWEPPEEPNGF-----------IRGYRVYYTHELHTPLSTWHKHNTDDSRLTTISGLVPDITYSLRVLGFTSVGDGPPSDVLQVKTQQGVPAQPTDFEAEAELDTRIMLTWLWPVQDQITKYELIYWEADSGDKTHVTFEPAGSYAV-ESLKPDT---LYKFTLA---ARSEMGLGVYTQPIE------------ARTAQSTPSAPPQEVHLLSLSSTSIQVSWVAPPAASRHGNIVRYSLAYQALSGEDQERHEVKDISADTSSYLLEGLEKWTEYQVWVKAHTDVGPGPESSSTRIRTKEDVPGAPPRRVEVDIINSTTLRVSWK-PPLAQKQ--HGQVRGYQVVYSRVENGEPRGQPTILDVALPEAQDAFITGLQAETSYSITVAAYTTKGDGARSKAKVVTTSGAVPGK-----PTMIISTTIGNTALIQWQPPKEMVGDLLGYTLQY------------KREE--DASFTVREFKRTDDHFTVTGLHKGATYIFKLSARNRAGNGEEYTKEVTTPEDVPGSYPQNLS---VVGLTTSSTELAWDPPPLAERNGKIVRYVVVYRDINSQQNH 966 HSP 3 Score: 138.272 bits (347), Expect = 5.164e-32 Identity = 217/963 (22.53%), Postives = 382/963 (39.67%), Query Frame = 1
Query: 265 LVLINSQIT--FTENDEAPKISLIIQSPNVLLFKSMILACSSTGHPVPSISWKINESPIEELKSPLKKLQNPPRIFSIKNYQNSVLVITQLIESDSNSVLICEAENNAGFD-SRQQQLKVISTETDIPSGFPVFQNNFFPIIKPYNSNVTLVCQAYGNPPPLIQWFKN-YELINESFTKIKILNDGNLLLVQVTREDKGIYHCQAQNTNGLRLSDPSTLDITSYPISPNSLIIERFASDNVEISWRSGLNDVTEQENFILHYREVPENITEKQIMSKFVYLTISEKKSIYKYNLKDLFPFTTYCIWMESENPLGVSPPTIALTVKTLPTSPQLSPRSITATSISNTAILVAWRPPERKFGKFKYYQIIYTNNDGFLPQHWRQFAVKDDNV-MLTHLIASELYHIRVKIVNEIGHGPLSKTISIKTIAGTLSQCPDFKITEIFQSHIKLQWGTPDPVKLFKLIQYNLLCWDVRLKIVNATAKSSTLF-PILNHNLSMNEMEYVLYLKNEKEIKCRLSAINSDGKGMPTE-IQASTVNKGVNY-QNLIHIDKIGSTYITFQWRPPSKFS----FDYFLWIYQIFDSEKLDRAVKLPKIKINISDSAS----AENGWFVYNYTNAFSSSRYILGLRYLCRDSTDILREYVHRSDLVSTMKSVPSDSPKDLVVKEIDSNSALVSWKPLDQVHSNGIITHYEVRYY-----APKKEESTERFINVSETSAILSNLKY-FHYVIYVRAFTKVGGGSWSNPKNYYRQNLEEFPIPTTIKGERKSETEINISWELPVLSEKNLAHAAIEGFIILYAPVESSPKWIKYTVQSKNLSAVIKGLEPDLRYQFQIAATNYAGFNGNFSEIV---QEMPKNFPNLNLKTVPDLRCSVQSSNRLKVEWSSPSISTDLLKFEIRYSGNLSYITEIGLKKSEFIDMESKSVNFETLVNRYDVTLENLQSNALYKIAVRA 3078
+VL QI F D P++ ++ ++ ++ + C+++G+P P ISW + P++ S + IK ++ L I ESD C A N+AG S L V P + P ++ L C A G P P ++W EL E I N+L + R+ Y C A ++ G+ + + + + + P P SLI+ + +V ++W SG + +++ YR I+S + + S +Y++ L P++ Y + + N +G PP+ + +T +P P S+ A +S T +LV W PPE G + Y++ YT+ W + D + ++ L+ Y +RV +G GP S + +KT G +Q DF+ + I L W P ++ K Y L+ W+ ++ K+ F P ++ V LK + K L+A + G G+ T+ I+A T + +H+ + ST I W P S + YQ E +R ++K +D++S W Y + + TD+ S + T + VP P+ + V I+S + VSWKP +G + Y+V Y P+ + + A ++ L+ Y I V A+T G G+ S K PT I T + I W+ P +L G+ + Y E + ++ ++ + + GL Y F+++A N AG +++ V +++P ++P NL V +++ ++ W P ++ K +RY + D+ S+ N + +T+ LQ++ Y I VRA
Sbjct: 135 IVLEEDQIPHGFPTIDMGPQLKVVERT------RTATMLCAASGNPDPEISWFKDFLPVDINGSNGR----------IKQLRSGALQIENSEESDQGKYE-CVAMNSAGTRYSAPANLYVRVRRVPPRFSIPPINHEVMP-----GGSLNLTCVAVGAPMPYVKWMTGEVELTKEEEMPI----GRNVLELTNIRQSAN-YTCVAISSLGM-IETTAQITVKALPRPPTSLIVTETTATSVTLTWDSGNPEPVSY--YVIQYRA---------IISDNGFQEVDGVAST-RYSIGGLSPYSEYEFRVMAVNNIGRGPPSGTVETRTSEQAPSSPPLSVQARMLSATTMLVQWEPPEEPNGFIRGYRVYYTHELHTPLSTWHKHNTDDSRLTTISGLVPDITYSLRVLGFTSVGDGPPSDVLQVKTQQGVPAQPTDFEAEAELDTRIMLTWLWPVQDQITK---YELIYWE-----ADSGDKTHVTFEPAGSYA--------VESLKPDTLYKFTLAARSEMGLGVYTQPIEARTAQSTPSAPPQEVHLLSLSSTSIQVSWVAPPAASRHGNIVRYSLAYQALSGEDQERH----EVKDISADTSSYLLEGLEKWTEY---------------QVWVKAHTDVGPGPESSSTRIRTKEDVPGAPPRRVEVDIINSTTLRVSWKPPLAQKQHGQVRGYQVVYSRVENGEPRGQPTILDVALPEAQDAFITGLQAETSYSITVAAYTTKGDGARSKAKVVTTSGAVPGK-PTMIISTTIGNTAL-IQWQPPKEMVGDLL-----GYTLQYKREEDASFTVREFKRTDD-HFTVTGLHKGATYIFKLSARNRAGNGEEYTKEVTTPEDVPGSYPQ-NLSVV------GLTTSSTELAWDPPPLAERNGKI-VRYV-------------VVYRDINSQQ-NHTNTTAQTRMTINGLQADTTYDIRVRA 992 HSP 4 Score: 88.9669 bits (219), Expect = 5.551e-17 Identity = 132/584 (22.60%), Postives = 231/584 (39.55%), Query Frame = 1
Query: 1126 YNLKDLFPFTTYCIWMESENPLGVSPPTIALTVKTLPTSPQLSPRSITATSISNTAILVAW--RPPERKFGKFKYYQIIYTNNDGFLPQHWRQFAVKD-----DNVMLTHLIASELYHIRVKIVNEIGHGPLSKTISIKTIAGTLSQCPDFKITEIFQSH-IKLQWGTPDPVKLFKLIQYNLLCWDVRLKIVNATAKSSTLFPILNHNLSMNEMEYVLYLKNEKEIKCRLSAINSDGKGMPTEIQASTVNKGV-NYQNLIHIDKIGSTYITFQWRPPSKFSFDYFLWIYQIFDSEKLDRAVKLPKIKINISDSASAENGWFVYNYTNAFSSSRYILGLRYLCRDSTDILREYVHRSDLVSTMKSVPSDSPKDLVVKEIDSNSALVSWKPLDQVHSNGIITHYEVRYYAPKKEESTERFIN-VSETSAILSNLKY-FHYVIYVRAFTKVGGG--SWSNPKNYYRQNLEEFPIPTTIKGERKSETEINISWELPVLSEKNLAHAAIEGFIILYAPVESSPKWIKYTVQSKNLSAVIKGLEPDLRYQFQIAATNYAGFNGNFSEIVQEMPKNFPNLNLKTVPDLRCS 2838
Y ++ L P T Y + + + +G+ T + +T ++P P+ + S+S+T+I V+W P + G Y + Y G + + VKD + +L L Y + VK ++G GP S + I+T P +I S +++ W P K ++ + + ++ N + IL+ L + ++ L+ E ++A + G G ++ + T + V +I IG+T + QW+PP + D + Q E V+ + +D + T + YI L R+ EY V+T + VP P++L V + ++S ++W P NG I Y V Y + S + N ++T ++ L+ Y I VRAFT GGG S S ++ EF +K KS + ++WE+P + + F ILY VQ +I L+PD Y F + + GN + +Q+ ++++T PDL S
Sbjct: 578 YAVESLKPDTLYKFTLAARSEMGLGVYTQPIEARTAQSTPSAPPQEVHLLSLSSTSIQVSWVAPPAASRHGNIVRYSLAYQALSG---EDQERHEVKDISADTSSYLLEGLEKWTEYQVWVKAHTDVGPGPESSSTRIRTKEDVPGAPPRRVEVDIINSTTLRVSWKPPLAQKQHGQVRGYQVVYS---RVENGEPRGQPT--ILDVALPEAQDAFITGLQAETSYSITVAAYTTKGDGARSKAKVVTTSGAVPGKPTMIISTTIGNTAL-IQWQPPKEMVGDLLGYTLQYKREEDASFTVR----EFKRTDDH--------FTVTGLHKGATYIFKLS--ARNRAGNGEEYTKE---VTTPEDVPGSYPQNLSVVGLTTSSTELAWDPPPLAERNGKIVRYVVVY---RDINSQQNHTNTTAQTRMTINGLQADTTYDIRVRAFTSKGGGPISPSIQSRTMATSMPEFTKNFGVKAVMKS--SVLLTWEVPETYKSQVP------FKILY-------NQQSVEVQGDLKRKLITRLQPDTDYSFVLMS------RGNSAGGLQQ------QVSIRTAPDLLTS 1105
BLAST of Protein tyrosine phosphatase receptor type D vs. Ensembl Cavefish
Match: ptprfa (protein tyrosine phosphatase receptor type Fa [Source:ZFIN;Acc:ZDB-GENE-020107-2]) HSP 1 Score: 716.842 bits (1849), Expect = 0.000e+0 Identity = 327/591 (55.33%), Postives = 430/591 (72.76%), Query Frame = 1
Query: 4051 ISDRPSISICNLYQYVTDLKANDCTLLQAEFETLNTNLDDRFTWQRSNIDSNKSKNRYANVVAYDHTSVLLTPVDDVIGSDYINANYIDGYQRQNAYIATQGPLPDTTDDFWRMVWEQRSNCIVMMTRLEERSGIKCHQYWPNRGFICYGQMIVSHIDTFVLAYYTIRLFEIRHSKYSEKREIQHFQFTAWPDHGVPKLSTPLLMFIRRVRSIGKIESCPKIVHCSAGVGRTGAFIVVDAQLERIKQEKNIDVFNYVSKIRCQRNYMVQTQAQYQFILETLLEAVEDGNTEVMACNFHAHVTKLSQIGISGSNQLSGFEMEFSKLNSLASNRGRHGVMLADFVKAAGNQAVNMTKNRVRNIIPYEWNRVVLNAIRGIEGSDYINASYIDGYRDRRAYIAAQSPIPSTVEDFWRMLWDQHCGVVIVLNQPHE---DKSHIYWPINKSIRYQFFVVDPVVEYNMPNYILREFKVTDARDGEFRALRQFQFTQWPNHGCPKESESILDFIRQVHKTKEQFGHMEPMVIHCNTGSGRTGVFIALSIVLDRLQQESVVDMYQTVKLLHKQRIGLVQTEEQYEFCYMAVLDYLSNYE 5814
+ + P I +C+L ++ LKAND E+E+++ +FTW+ SN++ NK KNRYANV+AYDH+ V+LTPVD V GSDYINANY+DGY++QNAYI TQGPLP+T DFWRMVWEQR+N IVMMT+LEE+S +KC QYWP+RG YG + VS +DT LA Y++R F + + SEKRE++ FQF AWPDHGVP+ TP+L F+RRV++ ++ P +VHCSAGVGRTG FIV+DA LER+K EK++D++ +V+ +R QRNYMVQT+ QY FI E LLEA G+TEV A + + H+ KL+Q + + ++ E+EF KL + ++ R F+ A N N KNR+ NI+P+E RV L IRG+EGSDYINAS++DGYR ++AYIA Q P+ T EDFWRMLW+ + +V++L + E +K H YWP +S RYQ+FVVDP+ EYNMP YILREFKVTDARDG+ R +RQFQFT WP G PK E +DFI QVHKTKEQFG P+ +HC+ G GRTGVFI LSIVL+R++ E VVD++QTVK L QR +VQTE+QY+ CY A L+YL +++
Sbjct: 1343 MREHPPIPVCDLADHIERLKANDGLRFSQEYESIDPG--QQFTWEHSNLEVNKPKNRYANVIAYDHSRVILTPVDGVPGSDYINANYVDGYRKQNAYIGTQGPLPETLSDFWRMVWEQRTNTIVMMTKLEEKSRVKCDQYWPSRGTETYGMIQVSMLDTVELATYSVRTFALYKNGSSEKREVRQFQFMAWPDHGVPEYPTPILAFLRRVKACNPPDAGPMVVHCSAGVGRTGCFIVIDAMLERMKHEKSVDIYGHVTCMRAQRNYMVQTEDQYVFIHEALLEAATCGHTEVPARSLYTHIQKLTQ--VPPGDTVTAMELEFKKLANSKAHTSR-------FISA--NLPCNKFKNRLVNIMPFESTRVCLQPIRGVEGSDYINASFLDGYRQQKAYIATQGPLAETTEDFWRMLWEHNSTIVVMLTKLREMGREKCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDARDGQSRTIRQFQFTDWPEQGVPKTGEGFIDFIGQVHKTKEQFGQDGPITVHCSAGVGRTGVFITLSIVLERMRYEGVVDLFQTVKTLRTQRPAMVQTEDQYQLCYRAALEYLGSFD 1920 HSP 2 Score: 152.14 bits (383), Expect = 2.912e-36 Identity = 228/996 (22.89%), Postives = 376/996 (37.75%), Query Frame = 1
Query: 370 LACSSTGHPVPSISWKINESPIEELKSPLKKLQNPPRIFSIKNYQNSVLVITQLIESDSNSVLICEAENNAGFDSRQQQLKVISTETDIPSGFPVFQNNFFPIIKPYNSNVTLVCQAYGNPPPLIQWFKNYEL--INESFTKIKILNDGNLLLVQVTREDKGIYHCQAQNTNGLRLSDPSTLDITSYPISPNSLIIERFASDNVEISWRSGLNDVTEQENFILHYREVPENITEKQIMSKFVYLTISEKKSIYK-----YNLKDLFPFTTYCIWMESENPLGVSPPTIALTVKTLPTSPQLSPRSITATSISNTAILVAW---RPPERKFGKFKYYQIIYTNNDGFLPQHWRQFAVKDDNVMLTHLIASELYHIRVKIVNEIGHGPLSKTISIKTIAGTLSQCP-DFKITEIFQSHIKLQWGTPDPVKLFKLIQYNLLCWDVRLKIVNATAKSSTLFPILN-HNLSMNEMEYVLYLKNEKEIKCRLSAINSDGKGMPTEIQASTVNKGVNYQNL-IHIDKIGSTYITFQWRPPSKFSFDYFLWIYQIFDSEKLDRAVKLPKIKINISDSASAENGWFVYNYTNAFSSSRYILGLRYLCRDSTDILREYVHRSDLVSTMKSVPSDSPKDLVVKEIDSNSALVSWKPLDQVHSNGIITHYEVRYYAPKKEESTE---RFINVSETSAILSNL-KYFHYVIYVRAFTKVGGGSWSNPKNYYRQNLEEFPIPTTIKGERKSETEINISWELPVLSEKNLAHAAIEGFIILYAPVESSPKWIKYTVQSKNL----SAVIKGLEPDLRYQFQIAATNYAGFNGNFSEIVQEMPKNFPNLNLKTVPDLRCSVQSSNRLKVEWSSP-SISTDLLKFEIRYSGNLSYITEIGLKKSEFIDMESKSVNFETLVNRYDVTLENLQSNALYKIAVRAIYQNKELYESHRETTCDTMPAVPNLVKPPIIVGLDEEKSKVIIKLHRCSQRNGKISYYFVIVAAFQGNKNQ 3291
C + G P P I+W +K K + + SVL I L ++ C A N+ G + +L V+ E IP GFP + T++C A GNP P I WFK++ IN S +IK L G L + D+G Y C A N+ G R S P+ L + + P RF+ + ++V + L V + + M+ V LT E+ I + N++ +T C+ + S LG+ T +TVK LP P S+ T + T++ + W P + +Y II +++GF V + L Y RV VN IG GP S T+ +T S P + + + + +QW P+ F +R V T + T + HN + + + L + R+ S G G P+++ +GV Q + T I W P + + IY DS P + +S + +Y +T A +R +GL + T +S PS P+++ + + S S VSW +G I Y + Y A E+ + I+ +S +L L K+ Y ++V+A T VG G S+ + P ++ + + T + +SW+ P L++K H + G+ ++Y+ VE+ + T+ L A I GL+ + Y +AA G V P P + S N ++W P + DLL + ++Y K+ E D F+ + + VT + + ++K++ R N E Y T D + P + +VGL +++ ++RNGKI Y V+ +N
Sbjct: 64 FVCQAVGEPKPRITW---------MKKGKKVSSQRFEVIEFDDGSGSVLRIQPLRTHRDEAIYECTATNSVGEINTSAKLIVLE-EDQIPHGFPTIDMGPQLKVVERTRTATMLCAASGNPDPEISWFKDFLPVDINGSNGRIKQLRSGALQIENSEESDQGKYECVAMNSAGTRYSAPANLYVRVRRVPP------RFSIPPIN-------HEVMPGGSLNLTCVAVGAPMPYVKWMTGEVELTKEEEMPIGRNVLELTNIRQSANYT--CVAISS---LGMIETTAQITVKALPRPPT----SLIVTETTATSVTLTWDSGNPEPVSYYVIQYRAII--SDNGFQEVD----GVASTRYSIGGLSPYSEYEFRVMAVNNIGRGPPSGTVETRTSEQAPSSPPLSVQARMLSATTMLVQWEPPEEPNGF-----------IRGYRVYYTHELHTPLSTWHKHNTDDSRLTTISGLVPDITYSLRVLGFTSVGDGPPSDVLQVKTQQGVPAQPTDFEAEAELDTRIMLTWLWPVQDQITKYELIYWEADSGDKTHVTFEPAGSYAV-ESLKPDT---LYKFTLA---ARSEMGLGVYTQPIE------------ARTAQSTPSAPPQEVHLLSLSSTSIQVSWVAPPAASRHGNIVRYSLAYQALSGEDQERHEVKDISADTSSYLLEGLEKWTEYQVWVKAHTDVGPGPESSSTRIRTKEDVPGAPPRRVEVDIINSTTLRVSWK-PPLAQKQ--HGQVRGYQVVYSRVENGEPRGQPTILDVALPEAQDAFITGLQAETSYSITVAAYTTKGDGARSKAKVVTTSGAVPGK-----PTMIISTTIGNTALIQWQPPKEMVGDLLGYTLQY------------KREE--DASFTVREFKRTDDHFTVTGLHKGATYIFKLSARNRAGNGEEYTKEVTTPEDVPGSYPQNLS---VVGLTTSSTELAWDPPPLAERNGKIVRYVVVYRDINSQQNH 966 HSP 3 Score: 138.272 bits (347), Expect = 5.916e-32 Identity = 217/963 (22.53%), Postives = 382/963 (39.67%), Query Frame = 1
Query: 265 LVLINSQIT--FTENDEAPKISLIIQSPNVLLFKSMILACSSTGHPVPSISWKINESPIEELKSPLKKLQNPPRIFSIKNYQNSVLVITQLIESDSNSVLICEAENNAGFD-SRQQQLKVISTETDIPSGFPVFQNNFFPIIKPYNSNVTLVCQAYGNPPPLIQWFKN-YELINESFTKIKILNDGNLLLVQVTREDKGIYHCQAQNTNGLRLSDPSTLDITSYPISPNSLIIERFASDNVEISWRSGLNDVTEQENFILHYREVPENITEKQIMSKFVYLTISEKKSIYKYNLKDLFPFTTYCIWMESENPLGVSPPTIALTVKTLPTSPQLSPRSITATSISNTAILVAWRPPERKFGKFKYYQIIYTNNDGFLPQHWRQFAVKDDNV-MLTHLIASELYHIRVKIVNEIGHGPLSKTISIKTIAGTLSQCPDFKITEIFQSHIKLQWGTPDPVKLFKLIQYNLLCWDVRLKIVNATAKSSTLF-PILNHNLSMNEMEYVLYLKNEKEIKCRLSAINSDGKGMPTE-IQASTVNKGVNY-QNLIHIDKIGSTYITFQWRPPSKFS----FDYFLWIYQIFDSEKLDRAVKLPKIKINISDSAS----AENGWFVYNYTNAFSSSRYILGLRYLCRDSTDILREYVHRSDLVSTMKSVPSDSPKDLVVKEIDSNSALVSWKPLDQVHSNGIITHYEVRYY-----APKKEESTERFINVSETSAILSNLKY-FHYVIYVRAFTKVGGGSWSNPKNYYRQNLEEFPIPTTIKGERKSETEINISWELPVLSEKNLAHAAIEGFIILYAPVESSPKWIKYTVQSKNLSAVIKGLEPDLRYQFQIAATNYAGFNGNFSEIV---QEMPKNFPNLNLKTVPDLRCSVQSSNRLKVEWSSPSISTDLLKFEIRYSGNLSYITEIGLKKSEFIDMESKSVNFETLVNRYDVTLENLQSNALYKIAVRA 3078
+VL QI F D P++ ++ ++ ++ + C+++G+P P ISW + P++ S + IK ++ L I ESD C A N+AG S L V P + P ++ L C A G P P ++W EL E I N+L + R+ Y C A ++ G+ + + + + + P P SLI+ + +V ++W SG + +++ YR I+S + + S +Y++ L P++ Y + + N +G PP+ + +T +P P S+ A +S T +LV W PPE G + Y++ YT+ W + D + ++ L+ Y +RV +G GP S + +KT G +Q DF+ + I L W P ++ K Y L+ W+ ++ K+ F P ++ V LK + K L+A + G G+ T+ I+A T + +H+ + ST I W P S + YQ E +R ++K +D++S W Y + + TD+ S + T + VP P+ + V I+S + VSWKP +G + Y+V Y P+ + + A ++ L+ Y I V A+T G G+ S K PT I T + I W+ P +L G+ + Y E + ++ ++ + + GL Y F+++A N AG +++ V +++P ++P NL V +++ ++ W P ++ K +RY + D+ S+ N + +T+ LQ++ Y I VRA
Sbjct: 135 IVLEEDQIPHGFPTIDMGPQLKVVERT------RTATMLCAASGNPDPEISWFKDFLPVDINGSNGR----------IKQLRSGALQIENSEESDQGKYE-CVAMNSAGTRYSAPANLYVRVRRVPPRFSIPPINHEVMP-----GGSLNLTCVAVGAPMPYVKWMTGEVELTKEEEMPI----GRNVLELTNIRQSAN-YTCVAISSLGM-IETTAQITVKALPRPPTSLIVTETTATSVTLTWDSGNPEPVSY--YVIQYRA---------IISDNGFQEVDGVAST-RYSIGGLSPYSEYEFRVMAVNNIGRGPPSGTVETRTSEQAPSSPPLSVQARMLSATTMLVQWEPPEEPNGFIRGYRVYYTHELHTPLSTWHKHNTDDSRLTTISGLVPDITYSLRVLGFTSVGDGPPSDVLQVKTQQGVPAQPTDFEAEAELDTRIMLTWLWPVQDQITK---YELIYWE-----ADSGDKTHVTFEPAGSYA--------VESLKPDTLYKFTLAARSEMGLGVYTQPIEARTAQSTPSAPPQEVHLLSLSSTSIQVSWVAPPAASRHGNIVRYSLAYQALSGEDQERH----EVKDISADTSSYLLEGLEKWTEY---------------QVWVKAHTDVGPGPESSSTRIRTKEDVPGAPPRRVEVDIINSTTLRVSWKPPLAQKQHGQVRGYQVVYSRVENGEPRGQPTILDVALPEAQDAFITGLQAETSYSITVAAYTTKGDGARSKAKVVTTSGAVPGK-PTMIISTTIGNTAL-IQWQPPKEMVGDLL-----GYTLQYKREEDASFTVREFKRTDD-HFTVTGLHKGATYIFKLSARNRAGNGEEYTKEVTTPEDVPGSYPQ-NLSVV------GLTTSSTELAWDPPPLAERNGKI-VRYV-------------VVYRDINSQQ-NHTNTTAQTRMTINGLQADTTYDIRVRA 992 HSP 4 Score: 88.9669 bits (219), Expect = 5.696e-17 Identity = 132/584 (22.60%), Postives = 231/584 (39.55%), Query Frame = 1
Query: 1126 YNLKDLFPFTTYCIWMESENPLGVSPPTIALTVKTLPTSPQLSPRSITATSISNTAILVAW--RPPERKFGKFKYYQIIYTNNDGFLPQHWRQFAVKD-----DNVMLTHLIASELYHIRVKIVNEIGHGPLSKTISIKTIAGTLSQCPDFKITEIFQSH-IKLQWGTPDPVKLFKLIQYNLLCWDVRLKIVNATAKSSTLFPILNHNLSMNEMEYVLYLKNEKEIKCRLSAINSDGKGMPTEIQASTVNKGV-NYQNLIHIDKIGSTYITFQWRPPSKFSFDYFLWIYQIFDSEKLDRAVKLPKIKINISDSASAENGWFVYNYTNAFSSSRYILGLRYLCRDSTDILREYVHRSDLVSTMKSVPSDSPKDLVVKEIDSNSALVSWKPLDQVHSNGIITHYEVRYYAPKKEESTERFIN-VSETSAILSNLKY-FHYVIYVRAFTKVGGG--SWSNPKNYYRQNLEEFPIPTTIKGERKSETEINISWELPVLSEKNLAHAAIEGFIILYAPVESSPKWIKYTVQSKNLSAVIKGLEPDLRYQFQIAATNYAGFNGNFSEIVQEMPKNFPNLNLKTVPDLRCS 2838
Y ++ L P T Y + + + +G+ T + +T ++P P+ + S+S+T+I V+W P + G Y + Y G + + VKD + +L L Y + VK ++G GP S + I+T P +I S +++ W P K ++ + + ++ N + IL+ L + ++ L+ E ++A + G G ++ + T + V +I IG+T + QW+PP + D + Q E V+ + +D + T + YI L R+ EY V+T + VP P++L V + ++S ++W P NG I Y V Y + S + N ++T ++ L+ Y I VRAFT GGG S S ++ EF +K KS + ++WE+P + + F ILY VQ +I L+PD Y F + + GN + +Q+ ++++T PDL S
Sbjct: 578 YAVESLKPDTLYKFTLAARSEMGLGVYTQPIEARTAQSTPSAPPQEVHLLSLSSTSIQVSWVAPPAASRHGNIVRYSLAYQALSG---EDQERHEVKDISADTSSYLLEGLEKWTEYQVWVKAHTDVGPGPESSSTRIRTKEDVPGAPPRRVEVDIINSTTLRVSWKPPLAQKQHGQVRGYQVVYS---RVENGEPRGQPT--ILDVALPEAQDAFITGLQAETSYSITVAAYTTKGDGARSKAKVVTTSGAVPGKPTMIISTTIGNTAL-IQWQPPKEMVGDLLGYTLQYKREEDASFTVR----EFKRTDDH--------FTVTGLHKGATYIFKLS--ARNRAGNGEEYTKE---VTTPEDVPGSYPQNLSVVGLTTSSTELAWDPPPLAERNGKIVRYVVVY---RDINSQQNHTNTTAQTRMTINGLQADTTYDIRVRAFTSKGGGPISPSIQSRTMATSMPEFTKNFGVKAVMKS--SVLLTWEVPETYKSQVP------FKILY-------NQQSVEVQGDLKRKLITRLQPDTDYSFVLMS------RGNSAGGLQQ------QVSIRTAPDLLTS 1105
BLAST of Protein tyrosine phosphatase receptor type D vs. Ensembl Cavefish
Match: PTPRD (protein tyrosine phosphatase receptor type D [Source:HGNC Symbol;Acc:HGNC:9668]) HSP 1 Score: 716.842 bits (1849), Expect = 0.000e+0 Identity = 338/606 (55.78%), Postives = 441/606 (72.77%), Query Frame = 1
Query: 4006 SDSIKLRIGSQKSENISDRPSISICNLYQYVTDLKANDCTLLQAEFETLNTNLDDRFTWQRSNIDSNKSKNRYANVVAYDHTSVLLTPVDDVIGSDYINANYIDGYQRQNAYIATQGPLPDTTDDFWRMVWEQRSNCIVMMTRLEERSGIKCHQYWPNRGFICYGQMIVSHIDTFVLAYYTIRLFEIRHSKYSEKREIQHFQFTAWPDHGVPKLSTPLLMFIRRVRSIGKIESCPKIVHCSAGVGRTGAFIVVDAQLERIKQEKNIDVFNYVSKIRCQRNYMVQTQAQYQFILETLLEAVEDGNTEVMACNFHAHVTKLSQIGISGSNQLSGFEMEFSKLNSLASNRGRHGVMLADFVKAAGNQAVNMTKNRVRNIIPYEWNRVVLNAIRGIEGSDYINASYIDGYRDRRAYIAAQSPIPSTVEDFWRMLWDQHCGVVIVLNQPHE---DKSHIYWPINKSIRYQFFVVDPVVEYNMPNYILREFKVTDARDGEFRALRQFQFTQWPNHGCPKESESILDFIRQVHKTKEQFGHMEPMVIHCNTGSGRTGVFIALSIVLDRLQQESVVDMYQTVKLLHKQRIGLVQTEEQYEFCYMAVLDYLSNYE 5814
+D ++LR + ++ ++ P I I +L ++ LKAND E+E+++ +FTW+ SN++ NK+KNRYANV+AYDH+ VLL+ +D + GSDYINANYIDGY++QNAYIATQG LP+T DFWRMVWEQRS IVMMT+LEERS +KC QYWP RG YG + V+ +DT LA Y +R F + + SEKRE++ FQFTAWPDHGVP+ TP L F+RRV++ ++ P +VHCSAGVGRTG FIV+DA LERIK EK +D++ +V+ +R QRNYMVQT+ QY FI + LLEAV GNTEV A N +A++ KL+QI +G N ++G E+EF +L + ++ R F+ A N N KNR+ NI+PYE RV L IRG+EGSDYINAS+IDGYR ++AYIA Q P+ T EDFWRMLW+ + +V++L + E +K H YWP +S RYQ+FVVDP+ EYNMP YILREFKVTDARDG+ R +RQFQFT WP G PK E +DFI QVHKTKEQFG P+ +HC+ G GRTGVFI LSIVL+R++ E VVD++QTVK+L QR +VQTE+QY+FCY A L+YL +++
Sbjct: 1316 TDPVELRRLNFQTPGMASHPPIPIMDLADHLERLKANDNLKFSQEYESIDPG--QQFTWEHSNLEVNKAKNRYANVIAYDHSRVLLSAIDGIPGSDYINANYIDGYRKQNAYIATQGSLPETFGDFWRMVWEQRSANIVMMTKLEERSRVKCDQYWPTRGTETYGLIQVTLLDTVELATYCVRTFALYKNGSSEKREVRQFQFTAWPDHGVPEHPTPFLAFLRRVKACNPPDAGPMVVHCSAGVGRTGCFIVIDAMLERIKHEKTVDIYGHVTLMRAQRNYMVQTEDQYVFIHDALLEAVTCGNTEVPARNLYAYIQKLTQIE-TGEN-VTGMELEFKRLANTKAHTSR-------FISA--NLPCNKFKNRLVNIMPYESTRVCLQPIRGVEGSDYINASFIDGYRQQKAYIATQGPLAETTEDFWRMLWEHNSTIVVMLTKLREMGREKCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDARDGQSRTVRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKEQFGQDGPISVHCSAGVGRTGVFITLSIVLERMRYEGVVDIFQTVKMLRTQRPAMVQTEDQYQFCYRAGLEYLGSFD 1908 HSP 2 Score: 205.297 bits (521), Expect = 1.966e-52 Identity = 105/262 (40.08%), Postives = 153/262 (58.40%), Query Frame = 1
Query: 5092 NQAVNMTKNRVRNIIPYEWNRVVLNAIRGIEGSDYINASYIDGYRDRRAYIAAQSPIPSTVEDFWRMLWDQHCGVVIVLNQPHEDKSHI----YWPINKSIRYQFFVVDPVVEYNMPNYILREFKVTDARDGEFRALRQFQFTQWPNHGCPKESESILDFIRQVHKTKEQFGHMEPMVIHCNTGSGRTGVFIALSIVLDRLQQESVVDMYQTVKLLHKQRIGLVQTEEQYEFCYMAVLDYLSNYEKILEKSHLY*TYQDLSE 5865
N VN KNR N+I Y+ +RV+L+AI GI GSDYINA+YIDGYR + AYIA Q +P T DFWRM+W+Q ++++ + E++S + YWP + Y V + + Y +R F + E R +RQFQFT WP+HG P+ L F+R+V PMV+HC+ G GRTG FI + +L+R++ E VD+Y V L+ QR +VQTE+QY F + A+L+ ++ + +LY Q L++
Sbjct: 1376 NLEVNKAKNRYANVIAYDHSRVLLSAIDGIPGSDYINANYIDGYRKQNAYIATQGSLPETFGDFWRMVWEQRSANIVMMTK-LEERSRVKCDQYWPTRGTETYGLIQVTLLDTVELATYCVRTFALYKNGSSEKREVRQFQFTAWPDHGVPEHPTPFLAFLRRVKACNPP--DAGPMVVHCSAGVGRTGCFIVIDAMLERIKHEKTVDIYGHVTLMRAQRNYMVQTEDQYVFIHDALLEAVTCGNTEVPARNLYAYIQKLTQ 1634 HSP 3 Score: 124.02 bits (310), Expect = 1.330e-27 Identity = 181/783 (23.12%), Postives = 288/783 (36.78%), Query Frame = 1
Query: 376 CSSTGHPVPSISWKINESPIEELKSPLKKLQNPPRIFSIKNYQNSVLVITQLIESDSNSVLICEAENNAGFDSRQQQLKVISTETDIPSGFPVFQNNFFPIIKPYNSNVTLVCQAYGNPPPLIQWFKNYELINESFT--KIKILNDGNLLLVQVTREDKGIYHCQAQNTNGLRLSDPSTLDITS----------YPISPNSLIIERFASDNVE----------ISWRSGLNDVTEQENFILHYREVPENITEKQIMSKFVYLTISEKKSIYKYNLKDLFPFTTYCIWMESENPLGVSPPTIALTVKTLPTSPQLSPRSITATSISNTAILVAW---RPPERKF----GKFKYYQIIYTNNDGFLPQHWRQFAVKDDNVMLTHLIASELYHIRVKIVNEIGHGPLSKTISIKTIAGTLSQCP-DFKITEIFQSHIKLQWGTPDPVKLFKLIQYNLLCWDVRLKIVNATAKSSTLFPILNHNLSMNEMEYVLYLKNEKEIKCRLSAINSDGKGMPTEIQASTVNKGVNYQNL-IHIDKIGSTYITFQWRPPSKFSFDYFLWIYQIFDSEKLDRAVKLPKIKINISDSASAENGWFVYNYTNAFSSSRYILGLRYLCRDSTDILREYVHRSDLVSTMKSVPSDSPKDLVVKEIDSNSALVSWKPLDQVHSNGIITHYEVRYYAPKKEESTERFIN---VSETSAILSNL-KYFHYVIYVRAFTKVGGGSWSNPKNYYRQNLEEFPIPTTIKGERKSETEINISWELPVLSEKNLAHAAIEGFIILY 2619
C +TG P P I W + + + + SVL I L ++ C A N G S +L V+ E +P+GFP + T++C A GNP P I WFK++ +N + +IK L G L + Q D+G Y C A N +G R S P+ L + + I P I S N+ + W G D+T +++ + N+ E LT + + Y C+ M + LGV +TVK LP P + + T + T+I + W P + K KY + Y DG V + L Y RV VN IG GP S+ I KT S P + + + + W P+ +++ Y + + VN K + N N + L K ++ A S G G + GV Q + + T I W P + D + Y++ K ++ K +++ + + ++ F++ + L R S + Y + T ++ PS P+++ S + LVSWKP NGII Y ++Y A + E++T R I+ +L NL K+ Y + V A T VG G S P+ + P ++ E + + + + W PV N H I G+ + Y
Sbjct: 50 CQATGDPRPKIVWNKKGKRVSNQRF---------EVIEFDDGSGSVLRIQPLRTPRDEAIYECVASNTVGEISATTRLTVLR-EDQLPAGFPTIDMGPQLKVVERTRTATMLCAASGNPDPDISWFKDFLPVNTTNNNGRIKQLRSGALQIEQSEESDQGKYECVATNNDGTRYSAPANLYVRELREVRRVPPRFSIPPTDSEIMPGGSVNITCVAVGSPMPYVKWMLGSEDLTPEDDM-----PIGRNVLE---------LTDVRQSANYT------------CVAMST---LGVIEAVAQITVKALPKPPGV----LVVTERTATSITLTWDSGNPEPVSYYIIQHKSKYSEDSYKEIDG----------VATTRYSVGGLSPYSDYEFRVVAVNNIGRGPASEAIEDKTAEQAPSTAPRQVRGRMLSATTAIIHWEEPEEAN-GQIMGYRVYYTMDPSQHVNQWEKQI----VRNANFLT-----IQGLTPNKTYYIKVLAYTSVGDGPLSSDLQIIAKTGVPSQPMDFKAEAKSETSILLSWVAPPQSGQDNQITGYELLYKRKDEKEEK----RVSFESTTT-----YLLKDLRPFTTYSFQLAAR-----SRHGIGAYTNEIS-AETPQTQPSAPPQEVTCSSPSSTNILVSWKPPPVELQNGIIIKYTIQYAATEGEDTTTREISEIPPENVQYLLENLEKWTEYRVTVTAHTDVGPGPESLPQLIRTEEDVPSGPPRKVEVEAVNSSSVKVLWRSPV---PNRQHGQIRGYQVHY 751 HSP 4 Score: 119.783 bits (299), Expect = 2.075e-26 Identity = 186/868 (21.43%), Postives = 333/868 (38.36%), Query Frame = 1
Query: 313 PKISLIIQSPNVLLFKSMILACSSTGHPVPSISWKINESPIEELKSPLKKLQNPPRIFSIKNYQNSVLVITQLIESDSNSVLICEAENNAGFD-SRQQQLKV--ISTETDIPSGF--PVFQNNFFPIIKPYNSNVTLVCQAYGNPPPLIQWFKNYELINESFTKIKILNDGNLLLVQVTREDKGIYHCQAQNTNGLRLSDPSTLDITSYPISPNSLIIERFASDNVEISWRSGLNDVTEQENFILHYREVPENITEKQIMSKFVYLTISEKK----SIYKYNLKDLFPFTTYCIWMESENPLGVSPPTIALTVKTLPTSPQLSPRSITATSISNTAILVAWRPPERKFGKFKYYQIIYTNNDGFLPQHWRQFAVKDDNVM-LTHLIASELYHIRVKIVNEIGHGPLSKTISIKTIAGTLSQCPDFKITEIFQSHIKLQW-GTPDPVKLFKLIQYNLLCWDVRLKIVNATAKSSTLFPILNHNLSMNEMEYVLYLKNEKEIKCRLSAINSDG-----KGMPTEIQASTVNKGVNYQNLIHIDKIGSTYITFQWRPPSKFSFDYFLWIY--QIFDSEKLDRAVKLPKIKINISDSASAENGWFVYNYTNAFSSSRYILGLRYLCRDSTDILREYVHRSDLVSTMKSVPSDSPKDLVVKEIDSNSALVSWKPLDQVHSNGIITHYEVRYY-----APKK---------EESTERFINVSETSAILSNLKY-FHYVIYVRAFTKVGGGSWSNPKNYYRQNLEEFPIPTTIKGERKSETEINISWELPVLSEKNLAHAAIEGFIILYAPVESSPKWIKYTVQSKNLSAVIKGLEPDLRYQFQIAATNYAGFNGNFSEIVQEM------PKNFP 2799
P I + Q V ++ + C+++G+P P ISW + P+ + + IK ++ L I Q ESD C A NN G S L V + +P F P + P +V + C A G+P P ++W L +E T + G +L Y C A +T G+ + + + + + P P L++ + ++ ++W SG PE ++ I K Y S K+ + +Y++ L P++ Y + + N +G P + A+ KT +P +PR + +S T ++ W PE G+ Y++ YT + W + V++ N + + L ++ Y+I+V +G GPLS + I G SQ DFK ++ I L W P + ++ Y LL K + ST +L + L ++ I + I+++ P E+ S+ + ST I W+PP + + Y Q +E D + IS+ EN ++ ++ R + TD+ L+ T + VPS P+ + V+ ++S+S V W+ +G I Y+V Y P +++ + + +E +L++L+ Y + V A+T G G+ S PK + P + + + W P + H ++G+ + + + P + + +N K + Y F+++A N GF E V+E+ P FP
Sbjct: 131 PTIDMGPQLKVVERTRTATMLCAASGNPDPDISWFKDFLPVNTTNNNGR----------IKQLRSGALQIEQSEESDQGKYE-CVATNNDGTRYSAPANLYVRELREVRRVPPRFSIPPTDSEIMP-----GGSVNITCVAVGSPMPYVKWM----LGSEDLTPEDDMPIGRNVLELTDVRQSANYTCVAMSTLGV-IEAVAQITVKALPKPPGVLVVTERTATSITLTWDSG----------------NPEPVSYYIIQHKSKYSEDSYKEIDGVATTRYSVGGLSPYSDYEFRVVAVNNIGRGPASEAIEDKTAEQAPSTAPRQVRGRMLSATTAIIHWEEPEEANGQIMGYRVYYTMDPSQHVNQWEKQIVRNANFLTIQGLTPNKTYYIKVLAYTSVGDGPLSSDLQIIAKTGVPSQPMDFKAEAKSETSILLSWVAPPQSGQDNQITGYELLYKRKDEKEEKRVSFESTTTYLLKDLRPFTTYSFQLAARSRHGIGAYTNEISAETPQTQPSAPPQEVTCSSPS---------------STNILVSWKPPPVELQNGIIIKYTIQYAATEGEDTTTR------EISE-IPPENVQYLLENLEKWTEYRVTVTAH------TDVGPGPESLPQLIRTEEDVPSGPPRKVEVEAVNSSSVKVLWRSPVPNRQHGQIRGYQVHYVRMFNGEPVGHPVIKDILIDDAQWEYDDSTEYEMVLTDLQAETTYSVTVAAYTTKGDGARSKPK--LVTTMGAVPEKPRLMVSPTNMGTALLQWHPPPNT-----HGPLQGYRLRFGRKDVEPLTVIEFPEREN-HYTTKEIHKGASYTFRLSARNKVGFG---EETVKEISTSEDTPSGFP 922 HSP 5 Score: 112.464 bits (280), Expect = 4.300e-24 Identity = 178/723 (24.62%), Postives = 285/723 (39.42%), Query Frame = 1
Query: 793 KILNDGNLLLVQVTREDKGIYHCQAQNT---NGLRLSDPSTLDITSYPISPNSLIIERFASDNVEISWRSGLNDVTEQENFILHYREVPENITEKQIMSKFVYLTISEKKSIYKYNLKDLFPFTTYCIWMESENPLGVSPPTIALTVKTLPTSPQLSPRSITATSISNTAILVAWRPP--ERKFGKFKYYQIIYTNNDGFLPQHWRQFAVKDDNV--MLTHLIASELYHIRVKIVNEIGHGPLSKTISIKTIAGTLSQCP-DFKITEIFQSHIKLQWGTPDPVKLFKLIQYNLLCWDVRLKIVNATAKSSTLFPILNHNL---------SMNEMEYVLY-LKNEKEIKCRLSAINSDGKGMPTEIQASTVNKGVNYQNLIHIDKIGSTYITFQWRPP--SKFSFDYFLWIYQIFDSEKLDRAVKLPKIKINISDSASAENGWFVYNYTNAFSSSRYILGLRYLCRDSTDILREYVHRSDLVSTMKSVPSDSPKDLVVKEIDSNSALVSWKPLDQVHSNGIITHYEVRYYAPKKEES-TERFINVSETSAILSNLKY-FHYVIYVRAFTKVGGGSWSNPKNYYRQNLEE-FPIPTTIKGERKSETEINISWELPVLSEKNLAHAAIEGFIILYAPVESSPKWIKYTVQSKNLSAVIKGLEPDLRYQFQIAATNYAGFNGNFSEIVQEMPKNFPNLNLKTVPDLRCSVQSSNRLKVEWSSPSIST 2892
+I+ + N L +Q +K Y T +G SD + T P P E + ++ +SW + + Q+N I Y + + EK+ K V +S Y LKDL PFTTY + + + G+ T ++ +T T P P+ +T +S S+T ILV+W+PP E + G Y I Y +G + +NV +L +L Y + V ++G GP S I+T S P ++ + S +K+ W +P P + I+ ++ V P++ L E E VL L+ E ++A + G G ++ + T V + + + QW PP + + + D E L ++ P+ EN +YT R R+ E V +ST + PS P+ +V + + + VSW+P+ NGII Y ++Y S +E FI E++ IL LK Y I + AFT G G +S + Q L++ F +K K T + ++WE+P N A F ILY +S V K +I L+P+ +Y F + TN G V M P++ L+T P L S + V+ PS+ T
Sbjct: 465 QIVRNANFLTIQGLTPNKTYYIKVLAYTSVGDGPLSSDLQIIAKTGVPSQPMDFKAEAKSETSILLSWVAPPQ--SGQDNQITGYELLYKRKDEKE--EKRVSF-----ESTTTYLLKDLRPFTTYSFQLAARSRHGIGAYTNEISAETPQTQPSAPPQEVTCSSPSSTNILVSWKPPPVELQNGIIIKYTIQYAATEGEDTTTREISEIPPENVQYLLENLEKWTEYRVTVTAHTDVGPGPESLPQLIRTEEDVPSGPPRKVEVEAVNSSSVKVLWRSPVPNRQHGQIR------GYQVHYVRMFNGEPVGHPVIKDILIDDAQWEYDDSTEYEMVLTDLQAETTYSVTVAAYTTKGDGARSKPKLVTTMGAVPEKPRLMVSPTNMGTALLQWHPPPNTHGPLQGYRLRFGRKDVEPLT-VIEFPE----------REN-----HYTTKEIHKGASYTFRLSARNKVGFGEETVKE---ISTSEDTPSGFPQSIVAESATTTTIQVSWQPVLLAERNGIIIKYALQYKDINSPRSPSELFIAAPESTVILDGLKADTTYDIKMCAFTSKGPGPYSPSIQFRTQPLDQVFAKNFHVKAAMK--TSVLLTWEIP--DNYNPAQP----FTILYDNGQS------VEVDGKLTQKLITNLQPETQYSFLL--TNRGNSAGGLQHRVSTM--TAPDI-LRTKPYLIGKTNSDGMVTVQL--PSVQT 1132 HSP 6 Score: 59.3066 bits (142), Expect = 6.165e-8 Identity = 187/904 (20.69%), Postives = 339/904 (37.50%), Query Frame = 1
Query: 1027 ILHYREVPENITEKQIMSKFVYLTISEKKSIYKY-----------NLKDLFPFTTYCIWMESENPLGVSPPTIALTVKTLPTSPQLSPRSITATSISNTAILVAW-RPPER-KFGKFKYYQIIYTNNDGFLPQHWRQFAVKDDNVMLTHLIASELYHIRVKIVNEIGHGPLSKTISIKTIAGTLSQCP-DFKITEIFQSHIKLQWGTPDPVKLFKLIQYNLLCWDVRLKIVNATAKSSTLFPILNHNLSMNEMEYVLY-LKNEKEIKCRLSAINSDGKGMPTEIQASTVNKGV--NYQNLIHIDKIGSTYITFQWRPPSKFSFDYFLWIYQI-----FDSEKLDRAVKLPKIKINISDSASAENGWFVYNYTNAFSSSRYILGLRYLCRDST--DILREYVHRSD-------LVSTMKSVPSDSPKDLVVKEIDSNSALVSWKPLDQVHSNGIITHYEVRYYAPKKEESTERFINVSETSAILSNL-KYFHYVIYVRAFTKVGGGSWSNPKNYYRQNLEEFP--IPTTIKGERKSETEINISWELPVLSEKNLAHAAIEGFIILYAPVESSPKWIKYTVQSKNLSAVIKGLEPDLRYQFQIAATNYAGFNGNFSEIVQEMPKNFPNLNLKTVPDLRCSVQSSNRLKVEWSSPSISTDLLKFEIRYSGNLSYITEIGLKKSEFIDMESKSVNFETLVNRYDVTLENLQSNALYKIAVRAIYQNKELYESHRETTCDTMPAVPNLVKPPIIVGLDEEKSKVIIKLHRCSQRNGKISYYFVIVAAFQGNKNQQISFQEDTESYTFMELSVNT-----------RSNNAKGEYIAIMKDINDIFKVSGKDHSSVLLGDGTHDENHLSVNKKLEKNFNYRCFARVCLKYSNNSLCKSSPWSEPFRISDL 3603
I+H+ E PE QIM VY T+ + + ++ ++ L P TY I + + +G P + L + P P A + S T+IL++W PP+ + + Y+++Y D + R +L L Y ++ + G G + IS +T S P + + ++I + W P PV+L I + + T + + P N ++Y+L L+ E + ++A G G + Q + V + ++ + S+ + WR P + YQ+ F+ E V P IK + D A E Y+ S+ Y + L L ++T + Y + D LV+TM +VP + P+ L+V + +AL+ W P H G + Y +R+ E T E + K Y + A KVG G + + E+ P P +I E + T I +SW+ +L+E+N I + + Y + S + + + + ++ GL+ D Y ++ A G G +S +Q + + K ++ ++++S + + W P F I Y S + L + +++ ++ L NR + + LQ HR TM A L P ++G V ++L Q + K+ Y+++V + + + + D+ +E + R K A K++ F + S + GD NK+L Y F L+ S N++ +SP+S+P +D+
Sbjct: 431 IIHWEE-PEE-ANGQIMGYRVYYTMDPSQHVNQWEKQIVRNANFLTIQGLTPNKTYYIKVLAYTSVGDGPLSSDLQIIAKTGVPS-QPMDFKAEAKSETSILLSWVAPPQSGQDNQITGYELLYKRKDE--KEEKRVSFESTTTYLLKDLRPFTTYSFQLAARSRHGIGAYTNEISAETPQTQPSAPPQEVTCSSPSSTNILVSW-KPPPVELQNGIIIKYTIQYAATEGEDTTTREISEIPPEN-------VQYLLENLEKWTEYRVTVTAHTDVGPGPESLPQLIRTEEDVPSGPPRKVEVEAVNSSSVKVLWRSPVPNRQHGQIRGYQVHYVRMFNGE----PVGHPVIKDILIDDAQWE-----YD-----DSTEYEMVLTDLQAETTYSVTVAAYTTKGDGARSKPKLVTTMGAVP-EKPR-LMVSPTNMGTALLQWHPPPNTH--GPLQGYRLRFGRKDVEPLTVIEFPERENHYTTKEIHKGASYTFRLSARNKVGFGEETVKEI---STSEDTPSGFPQSIVAESATTTTIQVSWQPVLLAERN---GIIIKYALQYKDINSPRSPSELFIAAPESTVILDGLKADTTYDIKMCAFTSKG-PGPYSPSIQFRTQPLDQVFAKNF-HVKAAMKTS--VLLTWEIPDNYNPAQPFTILYDNGQSVEVDGKLTQKLITNLQPETQYSFLLTNRGN-SAGGLQ---------------------HR---VSTMTAPDILRTKPYLIGKTNSDGMVTVQLPSV-QTSEKVRGYYIVVVPLKKQRTGKFAKPWDSPDEMNLEELLKEINRTSGILRFRRQVEPKPYIAAYFKELPTEFTLG----DSKMYGDFE--------NKQLLNGHEYIFFVLAVLEISENTMYATSPYSDPVVSADI 1255
BLAST of Protein tyrosine phosphatase receptor type D vs. Ensembl Sea Lamprey
Match: ptpra (protein tyrosine phosphatase receptor type A [Source:ZFIN;Acc:ZDB-GENE-020107-1]) HSP 1 Score: 463.766 bits (1192), Expect = 1.408e-143 Identity = 241/592 (40.71%), Postives = 359/592 (60.64%), Query Frame = 1
Query: 4063 PSISICNLYQYVTDLKANDCTLLQAEFETLNTNLDDRFTWQRSNIDSNKSKNRYANVVAYDHTSVLLTPVDDVIGSDYINANYIDGYQRQNAYIATQG--PLPDTTDDFWRMVWEQRSNCIVMMTRLEERSGIKCHQYWPNRGFICYGQMIVSHIDTFVLAYYTIRLFEIRH----SKYSEKREIQHFQFTAWPDHGVPKLSTPLLMFIRRVRSIGKIESCPKIVHCSAGVGRTGAFIVVDAQLERIKQEKNIDVFNYVSKIRCQRNYMVQTQAQYQFILETLLEAVEDGNTEVMACNFHAHVTKLSQIGISGSNQLSGFEMEFSKLNSLASNRGRHGVMLADFVKAAGNQAVNMTKNRVRNIIPYEWNRVVLNAIRGIEGSDYINASYIDGYRDRRAYIAAQSPIPSTVEDFWRMLWD-QHCGVVIV--LNQPHEDKSHIYWPINKSIRYQFFVVDPVVEYNMPNYILREFKVTDARDGEFRALRQFQFTQWPNHGCPKESESILDFIRQVHKTKEQFGHMEPMVIHCNTGSGRTGVFIALSIVLDRLQQESVVDMYQTVKLLHKQRIGLVQTEEQYEFCYMAVLDYLSNY 5811
P +++ L + A+D L + EF +L + + T + ++ + NK KNRY N++ YD+ V LT ++ V SDYINA+Y++GYQ +N +IA QG P +T +D+WRM+WE + IVM+T L+ER KC QYWP++G YG + VS D VL YTIR F I+ R I F FT+WPD GVP +L F+++V++ + P +VHCSAGVGRTG FIV+DA L+ I+ E+ +DVF +V++IR QR MVQT QY FI + LLE G+TE+ + +H+ KL + +G E EF KL + V + + GN NM KNRV IIPY++NRV++ RG E +DYIN S+IDGYR + A++A Q P+ TVEDFWRM+W+ + C +V++ L + ++K YWP +I Y +++ E + +Y +R+F V++ R+ + R +RQF F WP G P++ + ++ I V K ++ G+ P+ +HC+ G+GRTG F AL +L+R++ E ++D++QTVK L QR +VQT EQYEFCY V +Y+ +
Sbjct: 165 PPLAVDRLEEEFNRRSADDNKLFREEFNSL-PSCPIQATCEAASKEENKEKNRYVNILPYDNFRVHLTSLEGVPDSDYINASYVNGYQEKNKFIAAQGKGPKEETLNDYWRMIWELNTATIVMVTNLKERKECKCAQYWPDQGCWTYGNLRVSVEDVTVLVDYTIRKFLIQVVGDIPNKKPPRLITQFHFTSWPDFGVPFAPIGMLKFLKKVKTCNPPYAGPIVVHCSAGVGRTGTFIVIDAMLDMIQTERKVDVFGFVTRIRAQRCQMVQTDMQYVFIYQALLEFQLYGDTELEVTSLESHLQKL--YNKNTPTGCTGLEDEFKKLTT---------VKIQNEKMRTGNLPANMKKNRVLQIIPYDFNRVIIPMKRGEEFTDYINGSFIDGYRQKDAFLAGQGPLQQTVEDFWRMVWEWRSCSIVMLTELEERGQEKCARYWPTEGTITYGDIIIELKQENSHDSYTVRDFSVSNTRENKSRQIRQFHFHGWPEIGIPEDGKGMISLIAAVQKQQQHTGN-HPITVHCSAGAGRTGTFCALCTILERVKTEGILDVFQTVKSLRTQRPHMVQTLEQYEFCYKVVQEYIEAF 743
BLAST of Protein tyrosine phosphatase receptor type D vs. Ensembl Sea Lamprey
Match: ptprsa (protein tyrosine phosphatase receptor type Sa [Source:ZFIN;Acc:ZDB-GENE-020107-3]) HSP 1 Score: 416.001 bits (1068), Expect = 1.890e-128 Identity = 212/449 (47.22%), Postives = 281/449 (62.58%), Query Frame = 1
Query: 4006 SDSIKLRIGSQKSENISDRPSISICNLYQYVTDLKANDCTLLQAEFETLNTNLDDRFTWQRSNIDSNKSKNRYANVVAYDHTSVLLTPVDDVIGSDYINANYIDGYQRQNAYIATQGPLPDTTDDFWRMVWEQRSNCIVMMTRLEERSGIKCHQYWPNRGFICYGQMIVSHIDTFVLAYYTIRLFEIRHSKYSEKREIQHFQFTAWPDHGVPKLSTPLLMFIRRVRSI--GKIESCPKIVHCSAGVGRTGAFIVVDAQLERIKQEKNIDVFNYVSKIRCQRNYMVQTQAQYQFILETLLEAVEDGNTEVMACNFHAHVTKLSQIGISGSNQLSGFEMEFSKLNSLASNRGRHGVMLADFVKAAGNQAVNMTKNRVRNIIPYEWNRVVLNAIRGIEGSDYINASYIDGYRD-RRAYIAAQSPIPSTVEDFWRMLWDQHCGVVIVLNQPHE 5343
+D +++R + ++ + P I + +V LKAND L E+E+++ +FTW SN++ NK KNRYANVVAYDH+ V+L +D V GSDYINANYIDGY+R NAYIA+QGPL DT DFWRMVWEQRS+ IVMMT+LEER+ +KC QYWPNRG YG + V+ DT LA Y+ R F + S +E+R+++ FQFTAWPDHGVP+ TP+L F+RRVR+ + P IVHC G F V E + ++ V+ +R QRNYMVQT+ QY F+ L+EAV G TE A + HAH+ +LSQ + +G +EF +L L +G N KNR+ +IP + +RV L AIRG +GSDYINASYIDGYR +RAYIA Q P+P T ED WRMLW+Q+ +V++L + E
Sbjct: 159 ADPVQMRRLNHQTPGMEMHPPIPVSEFAGHVERLKANDNMLFSQEYESIDPG--QQFTWDHSNLEINKHKNRYANVVAYDHSRVILHTIDGVPGSDYINANYIDGYRRHNAYIASQGPLADTVADFWRMVWEQRSSTIVMMTKLEERARVKCDQYWPNRGSESYGLVQVTLTDTVELATYSTRSFTLTRSGCTERRDVRQFQFTAWPDHGVPEFPTPVLAFLRRVRAAWGSSADGGPLIVHCRQRSDVCGCFFVGLFMQEGHYGCITVSLYLQVTCMRAQRNYMVQTEEQYAFVHTALVEAVSSGCTETPARSLHAHLQRLSQSVSHTEPRTTGLHLEFQRLQM---------SKLRVSTAPSGALPCNKLKNRLLTVIPPDSSRVALQAIRGTQGSDYINASYIDGYRSQQRAYIATQGPLPETTEDLWRMLWEQNSTIVVMLTKLRE 596 HSP 2 Score: 172.94 bits (437), Expect = 3.904e-45 Identity = 95/262 (36.26%), Postives = 138/262 (52.67%), Query Frame = 1
Query: 5092 NQAVNMTKNRVRNIIPYEWNRVVLNAIRGIEGSDYINASYIDGYRDRRAYIAAQSPIPSTVEDFWRMLWDQHCGVVIVLNQPHED---KSHIYWPINKSIRYQFFVVDPVVEYNMPNYILREFKVTDARDGEFRALRQFQFTQWPNHGCPKESESILDFIRQVHKTKEQFGHMEPMVIHCNTGSGRTGVFIALSIVLDRLQQESVVDMYQTVKLLHKQRIGLVQTEEQYEFCYMAVLDYLSNYEKILEKSHLY*TYQDLSES 5868
N +N KNR N++ Y+ +RV+L+ I G+ GSDYINA+YIDGYR AYIA+Q P+ TV DFWRM+W+Q ++++ + E K YWP S Y V + Y R F +T + E R +RQFQFT WP+HG P+ +L F+R+V P+++HC S G F + + V +Y V + QR +VQTEEQY F + A+++ +S+ L+ Q LS+S
Sbjct: 219 NLEINKHKNRYANVVAYDHSRVILHTIDGVPGSDYINANYIDGYRRHNAYIASQGPLADTVADFWRMVWEQRSSTIVMMTKLEERARVKCDQYWPNRGSESYGLVQVTLTDTVELATYSTRSFTLTRSGCTERRDVRQFQFTAWPDHGVPEFPTPVLAFLRRVRAAWGSSADGGPLIVHCRQRSDVCGCFFVGLFMQEGHYGCITVSLYLQVTCMRAQRNYMVQTEEQYAFVHTALVEAVSSGCTETPARSLHAHLQRLSQS 480
BLAST of Protein tyrosine phosphatase receptor type D vs. Ensembl Sea Lamprey
Match: ca16b (carbonic anhydrase XVI b [Source:ZFIN;Acc:ZDB-GENE-080818-1]) HSP 1 Score: 377.481 bits (968), Expect = 1.140e-113 Identity = 220/613 (35.89%), Postives = 326/613 (53.18%), Query Frame = 1
Query: 4057 DRPSISICNLYQYVTDLKANDCTLLQAEFETLN-TNLDDRFTWQRSNIDSNKSKNRYANVVAYDHTSVLLTPV--DDVIGSDYINANYIDGYQRQNAYIATQGPLPDTTDDFWRMVWEQRSNCIVMMTRLEERSGIKCHQYWPNRGFICYGQMIVSHIDTFVLAYYTIRLFEIRHSKYSE-------------KREIQHFQFTAWPDHGVPKLSTPLLMFIRRVRSIGKIESCPKIVHC--SAGVGRTGAFIVVDAQLERIKQEKNIDVFNYVSKIRCQRNYMVQTQAQYQFILETLLEAVEDGNTEVMACNFHAHVTKLSQIGISGSNQLSGFEMEFSKLNSLASNRGRHGVMLADFVKAAGNQAVNMTKNRVRNIIPYEWNRVVLNAIRGIEGSDYINASYIDGYRDRRAYIAAQSPIPSTVEDFWRMLWDQHCGVVIVL--NQPHEDKSHIYWP-INKSIRYQFFVV-----DPVVEYNMPNYILREFKVTDARDGEFRALRQFQFTQWPNHGCP-KESESILDFIRQVHKTKEQFGHMEPMVIHCNTGSGRTGVFIALSIVLDRLQQESVVDMYQTVKLLHKQRIGLVQTEEQYEFCYMAVLDYLSNYE 5814
D ++ + ++V ++ EFE + D T + SN NK KNRY N+VAYDH+ V L P+ D SDYINANY+DGY RQ AYIA QGPL T DFWRMVWEQ + IVM+T L E+ KC QYWP+ YG ++V+ T LA YT+R F IR++K + +R + F +T WPD G P + P+L F+R+ + P +VHC SAGVGRTG +IV+D+ L++I+ ++V ++ IR QRNY+VQ Q QY FI E+LLEAV G TEV HA+ T + + + E + L + V ++F A + N KNR +I+P E +RV L+++ G+EG+DYINASYI GY +I Q P+P T DFWRM+WD + ++++L Q + +YWP +++ F V D + N ++ +F + +D +R +Q +WP+ P + I++ IR+ T++ P ++H G G F AL+ +L +L+++ VD++Q K+++ R G+ EQY F Y A L + E
Sbjct: 67 DGEALPVKLFARHVGEMHEGALHSFSQEFEEVQRCTADLGITAEHSNHPENKHKNRYVNIVAYDHSRVRLRPLPGKDSKHSDYINANYVDGYNRQKAYIAAQGPLKATFADFWRMVWEQNTGIIVMITNLVEKGRRKCDQYWPSESNEEYGNILVTLKSTRTLACYTVRHFTIRNTKLRKGTSQKSSARGRQNERLVVQFHYTQWPDMGTPDYALPVLTFVRKSSATRTDLMGPVVVHCRRSAGVGRTGTYIVLDSMLQQIRDSGTVNVLGFLKHIRTQRNYLVQPQEQYTFIHESLLEAVLTGETEVAPGQLHAYYTSILSPAATDVTRPVVTATENTHLEKQFRLVTQCSVRQSEFFSA--TKHCNKEKNRNSSIVPVERSRVGLSSLSGLEGTDYINASYITGYYRSNEFIVTQHPLPHTTRDFWRMIWDHNAQIIVMLPDGQGLAEDESVYWPGREEAMNCDDFTVTLINEDRLCLANEEQLVIHDFILECLQDDYVLEVRHYQCPRWPDTEGPLSNAFEIINVIREEATTRDG-----PTILHDEFGGVSAGTFCALTTLLHQLEEQESVDVFQVCKMVNLMRPGVFTDIEQYHFVYRAALSLIGTRE 672 HSP 2 Score: 158.303 bits (399), Expect = 7.820e-40 Identity = 98/318 (30.82%), Postives = 156/318 (49.06%), Query Frame = 1
Query: 4966 QIGISGSNQLSGFEMEFSKLNSLASNRGRHGVMLADFVKAAGNQAVNMTKNRVRNIIPYEWNRVVLNAIRGIEG--SDYINASYIDGYRDRRAYIAAQSPIPSTVEDFWRMLWDQHCGVVIVLNQPHED---KSHIYWPINKSIRYQFFVVDPVVEYNMPNYILREFKV--TDARDGEF-----------RALRQFQFTQWPNHGCPKESESILDFIRQVHKTKEQFGHMEPMVIHC--NTGSGRTGVFIALSIVLDRLQQESVVDMYQTVKLLHKQRIGLVQTEEQYEFCYMAVLDYLSNYEKILEKSHLY*TYQDL 5859
+G L F EF ++ ++ G N N KNR NI+ Y+ +RV L + G + SDYINA+Y+DGY ++AYIAAQ P+ +T DFWRM+W+Q+ G+++++ E K YWP + Y +V + Y +R F + T R G R + QF +TQWP+ G P + +L F+R+ T+ M P+V+HC + G GRTG +I L +L +++ V++ +K + QR LVQ +EQY F + ++L+ + E + L+ Y +
Sbjct: 79 HVGEMHEGALHSFSQEFEEVQRCTADLG--------ITAEHSNHPENKHKNRYVNIVAYDHSRVRLRPLPGKDSKHSDYINANYVDGYNRQKAYIAAQGPLKATFADFWRMVWEQNTGIIVMITNLVEKGRRKCDQYWPSESNEEYGNILVTLKSTRTLACYTVRHFTIRNTKLRKGTSQKSSARGRQNERLVVQFHYTQWPDMGTPDYALPVLTFVRKSSATRTDL--MGPVVVHCRRSAGVGRTGTYIVLDSMLQQIRDSGTVNVLGFLKHIRTQRNYLVQPQEQYTFIHESLLEAVLTGETEVAPGQLHAYYTSI 386
BLAST of Protein tyrosine phosphatase receptor type D vs. Ensembl Sea Lamprey
Match: ENSPMAT00000002738.1 (pep scaffold:Pmarinus_7.0:GL477626:22501:55781:-1 gene:ENSPMAG00000002497.1 transcript:ENSPMAT00000002738.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 355.525 bits (911), Expect = 9.374e-108 Identity = 205/578 (35.47%), Postives = 325/578 (56.23%), Query Frame = 1
Query: 4063 PSISICNLYQYVTDLKANDCTLLQAEFETLNTNLDDRFT-WQRSNIDSNKSKNRYANVVAYDHTSVLLTPVDDVIGSDYINANYID--GYQRQNAYIATQGPLPDTTDDFWRMVWEQRSNCIVMMTRLEERSGIKCHQYWPNRGFICYGQMIVSHIDTFVLAYYTIRLFEIRHSKYSEKREIQHFQFTAWPDHGVPKLSTPLLMFIRRVRSIGKIESCPKIVHC--SAGVGRTGAFIVVDAQLERIKQEKNIDVFNYVSKIRCQRNYMVQTQAQYQFILETLLEAVEDGNTEVMACNFHAHVTKLSQIGISGSNQLSGFEMEFSKLNSLASNRGRHGVMLADFVKAAGNQAVNMTKNRVRNIIPYEWNRVVLNAIRGIEGSDYINASYIDGYRDRRAYIAAQSPIPSTVEDFWRMLWDQHCGVVIVLNQ--PHEDKSHIYWPINKSIRYQFFVVDPVV---EYNMPNYILREFKVTDARDG--EFRALRQFQFTQWPNH-GCPKESESILDFIRQVHKTKEQFGHMEP-MVIHCNTGSGRTGVFIALSIVLDRLQQESVVDMYQTVKLLHKQRIGLVQ 5754
P+I + +L Q++ +K+ + + E+E+ LD + WQ + D N+ +NRY N++A H+ L V+ DY A Y++ GYQ+Q YIATQGPL +T DFWRMVW+++S+ IVM+T L E +KC +YWP+ G + V+ + T +LA Y IR F ++ Y + E++ F FT WPDHGVP +T LL F+RRV++ E+ P I HC SAG GRTG ++V+D LE +E IDV+N V ++R QR MVQT+ QY FI + LLEA G+T + A NF + +L++ + + + EF LN++ +A + N +KNRV+ +P + L + G + S+YINA+ +D Y A+I Q P+P+TV+DFWR+++D HC VI+LN+ P E YWP S++Y V+ + + ++ + I R ++ +DG E + ++ Q+ WP+H P S L +V + + E ++HC +G GR+G + A+S++ D ++ +SVVD++ VK L + +V+
Sbjct: 1 PAIRVADLLQHIGQMKSTEGCGFKEEYESF---LDGQSAPWQVAKKDENRGRNRYGNIIALKHSQKLKVRKQRVLSQDYTEA-YVEQHGYQKQRQYIATQGPLQETAVDFWRMVWQEKSSSIVMVTNLVEVGRVKCFKYWPD-DTQQLGDIAVTLLHTELLAEYVIRTFSVKRKGYFDALEVRQFHFTGWPDHGVPAFATGLLSFVRRVKASNPPEAGPIITHCRDSAGAGRTGCYVVIDVMLEMAGREGVIDVYNCVRELRLQRVNMVQTEEQYVFIHDVLLEACLCGDTAIPAANFRSAYLELTR--LDPQTHSTPLKEEFMTLNTVTPALRAEDCSIALLPR-------NSSKNRVKEALPPDRCLPFLLTLEG-DSSNYINAALLDSYHRPSAFIVTQHPLPNTVKDFWRLVFDYHCTSVIMLNEMRPSETCPQ-YWPEEGSLQYGAVHVETLSCCRDGDIISRIFRIHNISRPQDGHREVQHVQHLQYLGWPSHRDAPASPLSFLRVAGRVRRWHAELAEEEGRTLVHCLSGGGRSGTYCAVSVLCDMVKGQSVVDVFTAVKTLRNNKPDMVE 562 HSP 2 Score: 133.65 bits (335), Expect = 2.320e-32 Identity = 82/240 (34.17%), Postives = 132/240 (55.00%), Query Frame = 1
Query: 5104 NMTKNRVRNIIPYEWNRVVLNAIRGIEGSDYINASYID--GYRDRRAYIAAQSPIPSTVEDFWRMLW-DQHCGVVIVLN--QPHEDKSHIYWPINKSIRYQFFVVDPVVEYNMPNYILREFKVTDARDGEFRAL--RQFQFTQWPNHGCPKESESILDFIRQVHKTKEQFGHMEPMVIHC--NTGSGRTGVFIALSIVLDRLQQESVVDMYQTVKLLHKQRIGLVQTEEQYEFCYMAVLD 5796
N +NR NII + ++ + + + DY A Y++ GY+ +R YIA Q P+ T DFWRM+W ++ +V+V N + K YWP + + + V + + Y++R F V R G F AL RQF FT WP+HG P + +L F+R+V + P++ HC + G+GRTG ++ + ++L+ +E V+D+Y V+ L QR+ +VQTEEQY F + +L+
Sbjct: 46 NRGRNRYGNIIALKHSQKLKVRKQRVLSQDYTEA-YVEQHGYQKQRQYIATQGPLQETAVDFWRMVWQEKSSSIVMVTNLVEVGRVKCFKYWP-DDTQQLGDIAVTLLHTELLAEYVIRTFSVK--RKGYFDALEVRQFHFTGWPDHGVPAFATGLLSFVRRVKASNPP--EAGPIITHCRDSAGAGRTGCYVVIDVMLEMAGREGVIDVYNCVRELRLQRVNMVQTEEQYVFIHDVLLE 279
BLAST of Protein tyrosine phosphatase receptor type D vs. Ensembl Sea Lamprey
Match: ptprk (protein tyrosine phosphatase receptor type K [Source:ZFIN;Acc:ZDB-GENE-030131-9834]) HSP 1 Score: 366.311 bits (939), Expect = 8.587e-104 Identity = 208/590 (35.25%), Postives = 327/590 (55.42%), Query Frame = 1
Query: 4063 PSISICNLYQYVTDLKANDCTLLQAEFETLNTNLDDRFTWQRSNIDSNKSKNRYANVVAYDHTSVLLTPVDDVIGSDYINANYIDGYQRQNAYIATQGPLPDTTDDFWRMVWEQRSNCIVMMTRLEERSGIKCHQYWPNRGFICYGQMIVSHIDTFVLAYYTIRLFEIRHSKYSEKREIQHFQFTAWPDHGVPKLSTPLLMFIRRVRSIGKIESCPKIVHCSAGVGRTGAFIVVDAQLERIKQEKNIDVFNYVSKIRCQRNYMVQTQAQYQFILETLLEAVEDGNTEVMACNFH-AHVTKLSQIGISGSNQLSGFEMEFSKLNSLASNRGRHGVMLADFVKAAGNQAVNMTKNRVRNIIPYEWNRVVLNAIRGIEGSDYINASYIDGYRDRRAYIAAQSPIPSTVEDFWRMLWDQHCGVVIVLNQPHEDK-SHIYWPINKSIRYQFFVVDPVVEYNMP-NYILREFKVTD---ARDGEFRALRQFQFTQWP-NHGCPKESESILDFIRQVHKTKEQFGHMEPMVIHC---NTGSGRTGVFIALSIVLDRLQQESVVDMYQTVKLLHKQRIGLVQTEEQYEFCYMAVLDYL 5802
P++ + +L +++ +K + + E+E+ W + D N++KNRY N++AYDH+ V+L +D+ SDYINANY+DGY R + YIATQGPLPDT FWRM+W++RS I+M+T L E IKC +YWP+ G YG + V+ DT +L+ Y IR F + + + RE++ F FT WPDHGVP +T LL FIRR++++ + P +VHCSAG GRTG ++V+D L+ + E ID++N V ++R +R MVQT+ QY FI + +LEA G+T + A +F A+ L S SN + EF LN + +A + N KNR +++P + L I G + S+YINA+ +D YR A+I Q P+P+TV+DFWR+++D HC +++LN+ +K YWP + + V+ V +NM + I R F++ + +DG R + QF + WP P S L + + +E++G V+HC + ++ + + Q + ++ + + ++K GLV + QY+FCY L+YL
Sbjct: 896 PAVRVADLLEHIGQMKTGEGYGFKEEYESFFEG--QSAPWDVAKRDENRAKNRYGNIIAYDHSRVMLNVLDEEQNSDYINANYVDGYYRTHHYIATQGPLPDTVGGFWRMIWQERSASIIMVTNLVEVGRIKCCKYWPD-GSDVYGDIKVTLADTEMLSEYIIRTFRVERAGQEDIREVRQFHFTGWPDHGVPYHATGLLAFIRRIKALDPPHAGPLVVHCSAGAGRTGCYMVIDIMLDMAESEGVIDIYNCVRELRTRRVNMVQTEEQYVFIHDAMLEACLCGDTCIPAGDFRAAYAEMLRPDPQSSSNHIKD---EFQTLNMVTPPLRVEDCSIALLPR-------NHEKNRYHDVLPPDRCLPFLITING-DSSNYINAALMDSYRQPSAFIVTQHPLPNTVKDFWRLVFDYHCTSIVMLNELDSNKYCPQYWPEEGMLCHGPIQVE-FVAFNMEGDIITRTFRICNVARPQDG-CRMVEQFHYLGWPAGREVPTSRHSFLRLVLAAERWREEYGMDGRTVVHCLNPPPRLLSLPLLSLMATANNHMYQIIITELVEKIMAIYK---GLVNLQSQYQFCYDVALEYL 1466
BLAST of Protein tyrosine phosphatase receptor type D vs. Ensembl Yeast
Match: PTP1 (Phosphotyrosine-specific protein phosphatase; dephosphorylates a broad range of substrates in vivo, including Fpr3p; localized to the cytoplasm and the mitochondria; proposed to be a negative regulator of filamentation [Source:SGD;Acc:S000002389]) HSP 1 Score: 110.538 bits (275), Expect = 2.721e-26 Identity = 93/303 (30.69%), Postives = 131/303 (43.23%), Query Frame = 1
Query: 4144 ETLNTNLDDRFTWQRSNIDSNKSKNRYANVVAYDHTSVLLTPVDDVIGSDYINANYID----------GYQRQNAYIATQGPLPDTTDDFWRMVWEQRSNC------IVMMTRLEERSGIKCHQYWPNRGFICYGQMIVSHIDT----------------------FVLAYYTIRLFEIRHSK--YSEKREIQHFQFTAWPDHGVPKLSTPLLMFIRRVRSIGKIESCPKIVHCSAGVGRTGAFIVVDAQLERIKQEKNID-----------------VFNYVSKIRCQRNYMVQTQAQYQFI 4881
E N ++ R++ S N ++NRY N++ Y+ V L + G+DYINA+Y+ GY YIATQGP T D FW+M + NC IVM+T L E + KC+QYWP RG + I S ++ V YYT+ ++ + + + HF F W D P+ P++ S+ P IVHCSAGVGRTG FI +D + KNI + V ++R QR MVQT+ Q+ FI
Sbjct: 32 EATNGTVNSRWSLGVSIEPRNDARNRYVNIMPYERNRVHLKTLS---GNDYINASYVKVNVPGQSIEPGY-----YIATQGPTRKTWDQFWQMCYH---NCPLDNIVIVMVTPLVEYNREKCYQYWP-RGGVDDTVRIASKWESPGGANDMTQFPSDLKIEFVNVHKVKDYYTVTDIKLTPTDPLVGPVKTVHHFYFDLWKDMNKPEEVVPIMELCAHSHSLNS-RGNPIIVHCSAGVGRTGTFIALDHLMHDTLDFKNITERSRHSDRATEEYTRDLIEQIVLQLRSQRMKMVQTKDQFLFI 321 HSP 2 Score: 100.523 bits (249), Expect = 6.489e-23 Identity = 84/290 (28.97%), Postives = 130/290 (44.83%), Query Frame = 1
Query: 5104 NMTKNRVRNIIPYEWNRVVLNAIRGIEGSDYINASYID----------GYRDRRAYIAAQSPIPSTVEDFWRMLWDQHC---GVVIVLNQP----HEDKSHIYWP---INKSIRY----------------------QFFVVDPVVEYNMPNYILREFKVT--DARDGEFRALRQFQFTQWPNHGCPKESESILDFIRQVHKTKEQFGHMEPMVIHCNTGSGRTGVFIALSIVL----------------DRLQQESVVDMYQTVKL-LHKQRIGLVQTEEQYEFCYMAV 5790
N +NR NI+PYE NRV L + + G+DYINASY+ GY YIA Q P T + FW+M + +C +VIV+ P + +K + YWP ++ ++R +F V V +Y Y + + K+T D G + + F F W + P+E I++ H + P+++HC+ G GRTG FIAL ++ DR +E D+ + + L L QR+ +VQT++Q+ F Y A
Sbjct: 52 NDARNRYVNIMPYERNRVHL---KTLSGNDYINASYVKVNVPGQSIEPGY-----YIATQGPTRKTWDQFWQMCY-HNCPLDNIVIVMVTPLVEYNREKCYQYWPRGGVDDTVRIASKWESPGGANDMTQFPSDLKIEFVNVHKVKDY----YTVTDIKLTPTDPLVGPVKTVHHFYFDLWKDMNKPEEVVPIMELCAHSHSLNSR---GNPIIVHCSAGVGRTGTFIALDHLMHDTLDFKNITERSRHSDRATEEYTRDLIEQIVLQLRSQRMKMVQTKDQFLFIYHAA 325
BLAST of Protein tyrosine phosphatase receptor type D vs. Ensembl Yeast
Match: PTP2 (Nuclear phosphotyrosine-specific phosphatase involved in osmosensing; involved in the inactivation of mitogen-activated protein kinase (MAPK) during osmolarity sensing; dephosporylates Hog1p MAPK and regulates its localization; with Msg5p co-regulates the calcium signaling pathway [Source:SGD;Acc:S000005734]) HSP 1 Score: 84.7297 bits (208), Expect = 8.620e-17 Identity = 86/326 (26.38%), Postives = 128/326 (39.26%), Query Frame = 1
Query: 4210 SKNRYANVVAYDHTSVLLT-------------------------PVD----DVIGSDYINANYIDGYQRQN--AYIATQGPLPDTTDDFWRMVWEQRSNCIVMMTRLEERSGIKCHQYWPNRGFICYGQMI------VSHIDTFVLAYYTIRLFEIRHSKYSEKREIQH-------------------FQFTAWPDH-GVP--------KLSTPLLM----FIRRVRS----------------IGKIESCPKIVHCSAGVGRTGAFIVVDAQLERIKQEKN----IDVFNY--------VSKIRCQRNYMVQTQAQYQFILETLL 4896
+KNRY+N++ Y+H+ V L PVD +DYINANY+ Q YIATQ PLP T DDFW+++ + I+ + +E + K YW N + + + + +I+ VL + ++ ++ S+ ++ H Q+ W D GV K+ LL FI + + S P +VHCSAG GRTG F+ +D L + N IDV+N V+++R QR MVQ QY E LL
Sbjct: 410 TKNRYSNILPYEHSRVKLPHSPKPPAVSEASTTETKTDKSYPMCPVDAKNHSCKPNDYINANYLKLTQINPDFKYIATQAPLPSTMDDFWKVITLNKVKVIISLNSDDELNLRKWDIYWNNLSYSNHTIKLQNTWENICNINGCVLRVFQVKKTAPQNDNISQDCDLPHNGDLTSITMAVSEPFIVYQLQYKNWLDSCGVDMNDIIKLHKVKNSLLFNPQSFITSLEKDVCKPDLIDDNNSELHLDTANSSPLLVHCSAGCGRTGVFVTLDFLLSILSPTTNHSNKIDVWNMTQDLIFIIVNELRKQRISMVQNLTQYIACYEALL 735 HSP 2 Score: 57.3806 bits (137), Expect = 2.355e-8 Identity = 31/83 (37.35%), Postives = 44/83 (53.01%), Query Frame = 1
Query: 5593 GHMEPMVIHCNTGSGRTGVFIALSIVLDRLQQES-------VVDMYQ-----TVKLLHKQRIGLVQTEEQYEFCYMAVLDYLS 5805
+ P+++HC+ G GRTGVF+ L +L L + V +M Q V L KQRI +VQ QY CY A+L+Y +
Sbjct: 657 ANSSPLLVHCSAGCGRTGVFVTLDFLLSILSPTTNHSNKIDVWNMTQDLIFIIVNELRKQRISMVQNLTQYIACYEALLNYFA 739 HSP 3 Score: 53.5286 bits (127), Expect = 3.561e-7 Identity = 42/134 (31.34%), Postives = 60/134 (44.78%), Query Frame = 1
Query: 5065 LADFVKAAGNQAVNMTKNRVRNIIPYEWNRVVLN------AI-----------------------RGIEGSDYINASYID--GYRDRRAYIAAQSPIPSTVEDFWRMLWDQHCGVVIVLNQPHE---DKSHIYW 5364
+ D+ G Q+ TKNR NI+PYE +RV L A+ + +DYINA+Y+ YIA Q+P+PST++DFW+++ V+I LN E K IYW
Sbjct: 397 INDYELTEGIQS--FTKNRYSNILPYEHSRVKLPHSPKPPAVSEASTTETKTDKSYPMCPVDAKNHSCKPNDYINANYLKLTQINPDFKYIATQAPLPSTMDDFWKVITLNKVKVIISLNSDDELNLRKWDIYW 528
BLAST of Protein tyrosine phosphatase receptor type D vs. Ensembl Yeast
Match: PTP3 (Phosphotyrosine-specific protein phosphatase; involved in the inactivation of mitogen-activated protein kinase (MAPK) during osmolarity sensing; dephosporylates Hog1p MAPK and regulates its localization; localized to the cytoplasm [Source:SGD;Acc:S000000877]) HSP 1 Score: 53.5286 bits (127), Expect = 3.518e-7 Identity = 34/118 (28.81%), Postives = 53/118 (44.92%), Query Frame = 1
Query: 4210 SKNRYANVVAYDHTSVLL--------------TPVDDVIGSDYINANYID----------GYQ------RQNAYIATQGPLPDTTDDFWRMVWEQRSNCIVMMTRLEERSGIKCHQYW 4473
+KNRY ++ Y+H+ V+L + D I +YINANY+ +Q R+ YIATQ P+P T DF+ + ++ +T E KC++YW
Sbjct: 529 AKNRYKDIFPYEHSRVILKKGLQSSKGIKHSHSTSDGGILDNYINANYLSLPRFSVEQNSSFQTTTTTTRRVRYIATQAPMPSTVHDFYTCILNNGVPLVLSLTNDFENGIEKCYRYW 646 HSP 2 Score: 52.373 bits (124), Expect = 7.597e-7 Identity = 37/117 (31.62%), Postives = 56/117 (47.86%), Query Frame = 1
Query: 5113 KNRVRNIIPYEWNRVVLN----AIRGIEGS----------DYINASYIDGYR----------------DRRAYIAAQSPIPSTVEDFWRMLWDQHCGVVIVLNQPHE---DKSHIYW 5364
KNR ++I PYE +RV+L + +GI+ S +YINA+Y+ R R YIA Q+P+PSTV DF+ + + +V+ L E +K + YW
Sbjct: 530 KNRYKDIFPYEHSRVILKKGLQSSKGIKHSHSTSDGGILDNYINANYLSLPRFSVEQNSSFQTTTTTTRRVRYIATQAPMPSTVHDFYTCILNNGVPLVLSLTNDFENGIEKCYRYW 646
BLAST of Protein tyrosine phosphatase receptor type D vs. Ensembl Nematostella
Match: EDO46961 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RNP0]) HSP 1 Score: 605.52 bits (1560), Expect = 0.000e+0 Identity = 287/618 (46.44%), Postives = 409/618 (66.18%), Query Frame = 1
Query: 3970 CQDGTKLSPVLVSDSIKLRIGSQKSENISDRPSISICNLYQYVTDLKANDCTLLQAEFETLNTNLDDRFTWQRSNIDSNKSKNRYANVVAYDHTSVLLTPVDDVIGSDYINANYIDGYQRQNAYIATQGPLPDTTDDFWRMVWEQRSNCIVMMTRLEERSGIKCHQYWPNRGFICYGQMIVSHIDTFVLAYYTIRLFEIRHSKYSEKREIQHFQFTAWPDHGVPKLSTPLLMFIRRVRSIGKIESCPKIVHCSAGVGRTGAFIVVDAQLERIKQEKNIDVFNYVSKIRCQRNYMVQTQAQYQFILETLLEAVEDGNTEVMACNFHAHVTKLSQIGISGSNQLSGFEMEFSKLNSLASNRGRHGVMLADFVKAAGNQAVNMTKNRVRNIIPYEWNRVVLNAIRGIEGSDYINASYIDGYRDRRAYIAAQSPIPSTVEDFWRMLWDQHCGVVIVLNQPHE---DKSHIYWPINKSIRYQFFVVDPVVEYNMPNYILREFKVTDARDGEFRALRQFQFTQWPNHGCPKESESILDFIRQVHKTKEQFGHMEPMVIHCNTGSGRTGVFIALSIVLDRLQQESVVDMYQTVKLLHKQRIGLVQTEEQYEFCYMAVLDYLSNYE 5814
C+D K P SD +++R + ++ + D P IS+ +L +++ LKA++ + E+E++ FT S ++ NK KNRY N+ AYDH+ V L+ ++ + GSDYINAN+ DGY+++ AYIATQGP+ T DFWRMVWEQR+ IVM+TR EER +KC QYWP G Y + VS +D LA YTI +I S+ RE++HFQFT WPDHGVP TP L F+RRV+ ++ P +VHCSAGVGRTG FIV+D+ LER++ E+ +D++ +V+ +R QRNYMVQTQ QY F + +LEAV GNTEV A N H+ KL+++ G +++G E EF ++ + + ++G A A+N KNR+ NI+PYE RV ++ +RG+EGSDYINAS+IDGYR R +IA Q P+ TV+DFWRML +Q+ ++++L Q HE +K + YWP ++S R+Q+++VDP+ E+ P +++R+FKV DAR R ++QF F WP G PK E I+D I QV + EQ P+ +HC+ G GRTGVF AL IVL+R++ E VVD++QTVKLL QR +VQ++EQY FCY L+YL +++
Sbjct: 1270 CKDEEKSEP---SDPVEMRRLNFQTPAMIDHPPISVLDLPKHIAILKADNNSQFTQEYESIEPG--QTFTADSSQMECNKGKNRYPNIHAYDHSRVRLSYINGIEGSDYINANFCDGYRKERAYIATQGPMQHTAADFWRMVWEQRTFTIVMLTREEERGRVKCDQYWPTDGTDVYEGIEVSLVDWVELANYTISTLQICKEGASQPREVKHFQFTGWPDHGVPAHPTPFLAFLRRVKFYNPPDAGPIVVHCSAGVGRTGCFIVIDSMLERLRHEETVDIYGHVTVLRTQRNYMVQTQEQYIFSHDAILEAVSCGNTEVHARNLLHHIKKLTEL---GKGEVTGLEEEFKVVDPSQAKKHKYG---------AATLAINRPKNRLANILPYETTRVHISPVRGVEGSDYINASFIDGYRQRGLFIATQGPLQDTVDDFWRMLMEQNSNIIVMLTQLHEGEWEKCYKYWPTDRSARHQYYIVDPIAEHEYPQFVIRDFKVKDARSDTVRNIKQFHFLGWPETGVPKSGEGIIDLIGQVQRAYEQQEEEGPITVHCSDGVGRTGVFTALFIVLERMRSEGVVDLFQTVKLLRTQRPAMVQSQEQYLFCYKTALEYLGSFD 1870 HSP 2 Score: 124.405 bits (311), Expect = 3.107e-28 Identity = 203/936 (21.69%), Postives = 370/936 (39.53%), Query Frame = 1
Query: 364 MILACSSTGHPVPSISWKINESPIEELKSPLKKLQNPPRIFSIKNYQNSVLVITQLIESDSNSVLICEAENNAG--FDSRQQQLKV-ISTETDIPSGFPVFQNNFFPIIKPYNSNVTLVCQAYGNPPPLIQWFKNYELINESFTKIKILNDGNLLLVQVTREDKGIYHCQAQNTNGLRLSDPSTLDITSYPISPNSLIIERFASDNVEISWRS-GLNDVTEQENFILHYREVPENITEKQIMSKFVYLTISEKKSIYKYNLKDLFPFTTYCIWMESENPLGVSPPTIALTVKTLPTSPQLSPRSITATSISNTAILVAWRPPERKFGKFKYYQIIYTNNDGFLPQHWRQFAVKDDNVMLTHLIASELYHIRVKIVNEIGHGPLSKTISIKTIAGTLSQCPDFKITEIFQSHIKLQWGTPDPVKLFKLIQYNLLCWDVRLKIVNATAKSSTLFPILNHNLSMNEMEYVLYLKNEKEIKCRLSAINSDGKG-MPTEIQAST-VNKGVNYQNLIHIDKIGSTYITFQWRPPSKFSFDYFLWIYQIFDSEKLDRAVKLPKIKINISDSASAENGWFVYNYTNAFSSSRYILGLRYLCRDSTDILREYVHRSDLVSTMKSVPSDSPKDLVVKEIDSNSALVSWKPLDQVHSNGIITHYEVRY----------YAPKKEESTERFINVSETSAILSNLKYFHYVIYVRAFTKVGGGSWSNPKNYYRQNLEEFPIPTTIKGERKSE---TEINISWELPVLSEKNLAHAAIEGFIILYAPV--------ESSPKWIKYTVQSKNLSAVIKGLEPDLRYQFQIAATNYAGFNGNFSEIVQEMPKNFPNLNLKTVPDLRCSVQSSNRLKVEWSSPSI---STDLLKFEIRYSGNLSYITEIGLKKSEFIDMESKSVNFETLVNRYDVTLENLQSNALYKIAVRAI 3081
+ C++ G P P+I+W + PI + N PR+ + + + L IT L ESD N C A N G F S+ ++ I + P F +++V L C A G+P P I W + I+ +G L++ + R G Y C A + G R+ + + + P +P+ SD ++I+W G + VT E + YR + K + I+ + + + L PF++Y + + N LG S P++ T T P +PR+I A +S+T+ W PP G+ + Y++ Y+ + WR A ++ +T L + R+ N G GPLS+ +++KT G Q +++ + + I++ W P + + +DV KS + MN E ++ L K ++A + G G M + A T ++ + I ST + W PP + + + I K R K + ++ + ++ V + + F++ Y + ++ + + VST + VP+ +P+D+ ++ +S + V W P +G I Y V Y P + ES + + + Y I V A+T G G+ S + + + + P P + ER S +++ ++W + A IE + + YA + + K + +S + L + Y F ++ AG++ S ++ P L ++R SS ++V WS+P I +L + + Y+ ++ D+ K+V T N + V L+ L+ Y++ VRAI
Sbjct: 119 VTFTCAAVGTPTPNITWFKDRLPI---------VLNDPRVSVLSDGRK--LRITDLRESD-NGKYSCVARNALGMVFSSQAMPARLFIYLTLSVVRSKPEFTLRPQDKTVDPDTDVELKCSARGSPTPSIVWEVDGSRISG--------QNGELIIRGIQRS--GNYSCIADSNMG-RVQAYAYVTVRLLPFAPSRPNAASITSDAIKITWHPRGAHVVTSYE---VQYR----------LKGKTEWQEITNVRGMQSLVVSGLRPFSSYEFRVFAVNSLGRSRPSLMAEYTTSETKPGSAPRNIEAMGVSDTSFKAGWLPPISANGRIRGYRLYYSLDLLEDISQWRFMASSTNSTTVTGLTRQTTHFFRILAYNIAGDGPLSEVVAVKTQKGVPGQPRSVQLSVLSSTAIRVTWSPP------RYPGDGIFGYDVYYN------KSKQDMDTVIGAFQMNTKE-IMGLTPYTVYKVAVAAKSDKGVGPMSFVLTARTDEDRPSDAPQNIQGRSRDSTTLEISWDPPRPEHRNGLITHFTIKYRAKGQRGAKY--LTVDATKTS------VVLHNLDKFTN--YFIWVQASTKQGDGPFSD----KHTVSTAEDVPNGAPRDVRIRVHNSTTMTVKWNP-PTTKQDGKILGYMVFYTRVDDQGNQLRPPAQPESKDSMSEENHKVHLTGLAPETTYQIEVAAYTIKGDGARSVTR--LAKTMAQSPDPPFVYLERASGDPISDVTLAW-------RTSATGVIE-YKVRYAKSVRRLRGRDQGNLKMKEIKFKSHTTKQKFQSLANGIWYLFNVSLRTKAGWSPETSRWIEIPPGPPSGPPL----NVRAVAVSSTSVEVTWSAPDIWNRGGPILGYSVMYN-----------PANKRGDVTVKNV---TSPNIFKVVLKRLKKFREYEVRVRAI 962 HSP 3 Score: 81.6481 bits (200), Expect = 2.967e-15 Identity = 238/1139 (20.90%), Postives = 426/1139 (37.40%), Query Frame = 1
Query: 313 PKISLIIQSPNVLLFKSMILACSSTGHPVPSISWKINESPIEELKSPLKKLQNPPRIFSIKNYQNSVLVITQLIESDSNSVLICEAENNAGFDSRQQQ-----LKVISTETDIPSGFPVFQNNFFPIIKPYNSNVTLVCQAYGNPPPLIQWFKNYELINESFTKIKILNDGNLLLVQVTREDKGIYHCQAQNTNGLRLSDPSTL-DITSYPISPNSLIIERFASDNVEISWRSGLNDVTEQENFILHYR-----EVPENITEKQIMSKFVYLTISEKKSIYKYNLKDLFPFTTYCIWMESENPLGVSPPTIALTVKTLPTSPQLSPRSITATSISNTAILVAWRPPERKFGKFKYYQIIYTNNDGFLPQHWRQFAVKDDNVMLTHLIASELYHIRVKIVNEIGHGPLSKTISIKTIAGTLSQCP-DFKITEIFQSHIKLQWGTPDPVKLFKLIQYNLLCWDVRLK------IVNATAKSSTLFPILNHNLSMNEMEYVLYLKNEKEIKCRLSAINSDG--KGMPTEIQASTVNKGVNYQNLIHIDKIGSTYITFQWRPPSKFSFDYFLWIYQIFDSEKLDRAVKL-PKIKINISDSASAENGWF--------------VYNYTNAFSSSRYILGLRYLCRDSTDILREYVHRS--DLVSTMKSVPSDSPKDLVVKEIDSNSALVSWKPLDQVHSNGIITHYEVRYYAPKKEESTERFINVSETSAILSNLKYFHYVIYVRAFTKVGGGSWSNPKNYYRQ--NLEEFPIPTTIKGERKSETEINISWELPVLSEKNLAHAAIEGFIILYAPVESSPKWIKYTVQSKNL-SAVIKGLEPDLRYQFQIAATNYAGFNGNFSEIVQEMPKNFPNLNLKTVPDLRCSVQSSNRLKVEWSSPSISTDLLKFEIRYSGNLSYITEIGLKKSEFIDMESKSVNFETLVNRYDVTLENLQSNALYKIAVRAIYQNKELYESHRETTCDTMPAVPNLVKPPIIVGLDEEKSKVIIKLHRCSQRNGKISYYFVIVAAFQGNKNQQISFQEDTESYTFMELSVNTRSNNAKGE---YIAIMKDINDIFKVSGKDHSSVLLGDGTHDENHLSVNKKLEKNFNYRCFARVCLKYSNNSLC-KSSPWSEPFRIS 3597
P+ +L Q V + L CS+ G P PSI W+++ S I QN L+I + S + S C A++N G R Q ++++ P+ + + P ++V + +W + T ++ + L+V R Y + N L S PS + + T+ P S A + S+++G I YR ++ E+I++ + M+ S + L TT+ + + N G P + + VKT P PRS+ + +S+TAI V W PP Y + Y + + F + +M L +Y + V ++ G GP+S ++ +T S P + + + +++ W P P LI + + + + + V+AT S L HNL ++ Y I + S DG T A V G I + ST +T +W PP+ D + Y +F + D+ +L P + DS S EN V YT +R + L S D Y+ R+ D +S + S ++ ++ ++ + DQ G + E+++ K + ++F + L+N ++ + + +R TK G WS + + + P ++ S T + ++W P + + I G+ ++Y P V S N+ V+K L+ Y+ ++ A G G SE + K + + D+R S+ + +EW P I + L++ E+ + + + + ++ + LV T+ SNA+ + RA E + T P + P ++ + + ++LHR S++NG ISYY V+V +K+ + + + Y F + V RS G+ YIA K + D F L+GD + NK+L N Y F+R ++ + SSP+++P I+
Sbjct: 205 PEFTLRPQDKTVDPDTDVELKCSARGSPTPSIVWEVDGSRISG--------------------QNGELIIRGIQRSGNYS---CIADSNMG---RVQAYAYVTVRLLPFAPSRPNAASITSDAIKITWHPRGAHVVTSYEVQYRLKGKTEW--------QEITNVRGMQS---LVVSGLRPFSS-YEFRVFAVNSLGRSRPSLMAEYTTSETKPGSAPRNIEAMGVSDTSFKAGWLPPISANGRIRGYRLYYSLDLLEDISQWRFMAS----------STNSTTVTGLTRQTTHFFRILAYNIAGDGPLSEVVAVKTQKGVPG-QPRSVQLSVLSSTAIRVTWSPPRYPGDGIFGYDVYYNKSKQDMDTVIGAFQMNTKEIM--GLTPYTVYKVAVAAKSDKGVGPMSFVLTARTDEDRPSDAPQNIQGRSRDSTTLEISWDPPRPEHRNGLITHFTIKYRAKGQRGAKYLTVDATKTSVVL-----HNLD----KFTNYF-----IWVQASTKQGDGPFSDKHTVSTAEDVPNGAPRDVRIRVHN--STTMTVKWNPPTTKQ-DGKILGYMVFYTRVDDQGNQLRPPAQPESKDSMSEENHKVHLTGLAPETTYQIEVAAYTIKGDGARSVTRLAKTMAQSPDPPFVYLERASGDPISDVTLAWRTSATGVIEYKVRYAKSVRRLRGRDQ----GNLKMKEIKF---KSHTTKQKFQS-------LANGIWYLFNVSLR--TKAG---WSPETSRWIEIPPGPPSGPPLNVRAVAVSSTSVEVTWSAPDIWNRG---GPILGYSVMYNPANKRGDVTVKNVTSPNIFKVVLKRLKKFREYEVRVRAIGMLGM-GPASEPFIDRTKEDGKCHCR---DVRPRTVGSDWVILEWLPPRIDAGI-------DTPLTHADEV---RVDALTADVQTFKVQGLVPHMKYTVRLSASNAMGE-GPRA------------ELSISTKKGKPPALAKPTMLRDEMNNGLIPVELHRASEKNGPISYYLVVVVPL--DKDGKYPQGSNPDEY-FKK--VRRRSAREAGQVKPYIA-AKFLADQFP------KKFLVGDEGFKNQYGYYNKRLVANSYYTVFSRAYVQTDDGDFVYTSSPFTDPVLIT 1214 HSP 4 Score: 75.485 bits (184), Expect = 2.506e-13 Identity = 54/178 (30.34%), Postives = 83/178 (46.63%), Query Frame = 1
Query: 370 LACSSTGHPVPSISWKINESPIEELKSPLKKLQNPPRIFSIKNYQNSVLVITQLIESDSNSVLICEAENNAGFDSRQQQLKVISTETDIPSGFPVFQNNFFPIIKPYNS--NVTLVCQAYGNPPPLIQWFKNYELINESFTKIKILNDGNLLLVQVTRE-DKGIYHCQAQNTNGLRLS 894
+ C+ TG P+P+++W N S I ++Q IF++ ++ I L + CEA+N G R ++ T + P+GFP + P K S +VT C A G P P I WFK+ I + ++ +L+DG L + RE D G Y C A+N G+ S
Sbjct: 20 MICNVTGSPMPTLTWYKNGSVIRN-----SRIQ----IFTMP--YGGLIRIGPLRAKIHKATYECEADNGVGPPLRDSSTLIVHTASTKPAGFPRIAKH--PSFKQRRSGDDVTFTCAAVGTPTPNITWFKDRLPIVLNDPRVSVLSDGRKLRITDLRESDNGKYSCVARNALGMVFS 184
BLAST of Protein tyrosine phosphatase receptor type D vs. Ensembl Nematostella
Match: EDO43854 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RXI9]) HSP 1 Score: 516.924 bits (1330), Expect = 6.074e-165 Identity = 261/564 (46.28%), Postives = 367/564 (65.07%), Query Frame = 1
Query: 4138 EFETLNTNLDDRFTWQRSNIDSNKSKNRYANVVAYDHTSVLLTPVDDVIGSDYINANYIDGYQRQNAYIATQGPLPDTTDDFWRMVWEQRSNCIVMMTRLEERSGIKCHQYWPNRGFICYGQMIVSHIDTFVLAYYTIRLFEIRHSKYSEK-REIQHFQFTAWPDHGVPKLSTPLLMFIRRVRSIGKIESCPKIVHCSAGVGRTGAFIVVDAQLERIKQEKNIDVFNYVSKIRCQRNYMVQTQAQYQFILETLLEAVEDGNTEVMACNFHAHVTKLSQIGIS-GSNQLSGFEMEFSKLNSLASNRGRHGVMLADFVKAAGNQAVNMTKNRVRNIIPYEWNRVVLNAIRGIEGSDYINASYIDGYRDRRAYIAAQSPIPSTVEDFWRMLWDQHCGVVIVLNQPHED---KSHIYWPINKSIRYQFFVVDPVVEYNMPNYILREFKVTDARDGEFRALRQFQFTQWPNHGCPKESESILDFIRQVHKTKEQFGHMEPMVIHCNTGSGRTGVFIALSIVLDRLQQESVVDMYQTVKLLHKQRIGLVQTEEQYEFCYMAVLDYLSNYE 5814
E+E + N D+ FTW S +NK KNRYAN+VAYDH+ VLLTP++ V+ SDYINANYIDGY R A+IA+QGPLP+T DDFWRMVWEQ S IVM+T+LEER KC QYWP+RG YG + V+ +TF ++YY +R F + H + E+ R+++ + +T+WPDHGVP PLL +R V S + P IVHCSAGVGRTG FI +D+ L+R QE IDVF +V ++R +RN MVQT++QY FI + L+EAV G TEV A + + +L ++ + G+ + ++EF +L + RH + + N KNR NI+PYE RV L+ G GSDYINAS+IDG +AYIA Q+P+P T EDFWRMLW+Q V+++L + E K H YWP + S Y +V+ E +Y+LR+F +T + R +RQFQ T WP+ G P+ ++D I QV K ++Q G+ + +HC+ G GRTGVF A+SI+++R++ E ++D++QTV+ L QR +VQT++QYEFCY + +YL +++
Sbjct: 25 EYEMVQPN-DETFTWHHSLHPANKYKNRYANIVAYDHSRVLLTPLEGVLESDYINANYIDGYNRSGAFIASQGPLPETFDDFWRMVWEQGSAIIVMLTQLEERGRRKCDQYWPDRGTRNYGALRVTANETFHMSYYVLRTFLVSHMQEEEEPRQVRQYHYTSWPDHGVPAHPAPLLSMVRTVSSANPPTAGPMIVHCSAGVGRTGTFITLDSMLQRAAQEGTIDVFGFVRQMRNKRNLMVQTESQYVFIHDALVEAVICGVTEVDANKLASRIRELREVDPNIGTTYM---DLEFERL----TRDERHPTQF-----KSAMLSCNAAKNRYANILPYERTRVALHMRPGEVGSDYINASFIDGNHRLKAYIATQAPVPRTFEDFWRMLWEQESAVIVMLTREEEAGKLKCHRYWPSDGSRLYDKILVELTEELTYSDYVLRQFSLTHTEEKSSRIVRQFQCTDWPDSGLPESGVGLIDLIGQVEKWQQQSGNT-CITVHCSGGVGRTGVFCAVSILIERVKAEGLIDVFQTVQHLRLQRPAMVQTKDQYEFCYTTIQEYLESFD 574 HSP 2 Score: 220.705 bits (561), Expect = 5.219e-61 Identity = 115/275 (41.82%), Postives = 160/275 (58.18%), Query Frame = 1
Query: 4123 TLLQAEFETLNTNLDDRFTWQRSNIDSNKSKNRYANVVAYDHTSVLLTPVDDVIGSDYINANYIDGYQRQNAYIATQGPLPDTTDDFWRMVWEQRSNCIVMMTRLEERSGIKCHQYWPNRGFICYGQMIVSHIDTFVLAYYTIRLFEIRHSKYSEKREIQHFQFTAWPDHGVPKLSTPLLMFIRRVRSIGKIESCPKI-VHCSAGVGRTGAFIVVDAQLERIKQEKNIDVFNYVSKIRCQRNYMVQTQAQYQFILETLLEAVEDGNTEVMACNFH 4944
T + EFE L + ++ + + N +KNRYAN++ Y+ T V L +GSDYINA++IDG R AYIATQ P+P T +DFWRM+WEQ S IVM+TR EE +KCH+YWP+ G Y +++V + + Y +R F + H++ R ++ FQ T WPD G+P+ L+ I +V + I VHCS GVGRTG F V +ER+K E IDVF V +R QR MVQT+ QY+F T+ E +E + + NFH
Sbjct: 309 TYMDLEFERLTRDERHPTQFKSAMLSCNAAKNRYANILPYERTRVALHMRPGEVGSDYINASFIDGNHRLKAYIATQAPVPRTFEDFWRMLWEQESAVIVMLTREEEAGKLKCHRYWPSDGSRLYDKILVELTEELTYSDYVLRQFSLTHTEEKSSRIVRQFQCTDWPDSGLPESGVGLIDLIGQVEKWQQQSGNTCITVHCSGGVGRTGVFCAVSILIERVKAEGLIDVFQTVQHLRLQRPAMVQTKDQYEFCYTTIQEYLESFD---LYANFH 580
BLAST of Protein tyrosine phosphatase receptor type D vs. Ensembl Nematostella
Match: EDO45382 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RT25]) HSP 1 Score: 504.597 bits (1298), Expect = 2.209e-160 Identity = 257/579 (44.39%), Postives = 366/579 (63.21%), Query Frame = 1
Query: 4090 QYVTDLKANDCTLLQAEFETLNTNLDDRFTWQRSNIDSNKSKNRYANVVAYDHTSVLLTPVDDVIGSDYINANYIDGYQRQNAYIATQGPLPDTTDDFWRMVWEQRSNCIVMMTRLEERSGIKCHQYWPNRGFICYGQMIVSHIDTFVLAYYTIRLFEIRHSKYSEKREIQHFQFTAWPDHGVPKLSTPLLMFIRRVRSIGKIES-CPKIVHCSAGVGRTGAFIVVDAQLERIKQEKNIDVFNYVSKIRCQRNYMVQTQAQYQFILETLLEAVEDGNTEVMACNFHAHVTKLSQIGISGSNQLSGFEMEFSKLNSLASNRGRHGVMLADFVKAAGNQAVNMTKNRVRNIIPYEWNRVVLNAIRGIEGSDYINASYIDGYRDRRAYIAAQSPIPSTVEDFWRMLWDQHCGVVIVLNQPHED---KSHIYWPINKSIRYQFFVVDPVVEYNMPNYILREFKVTDARDGEFRALRQFQFTQWPNHGCPKESESILDFIRQVHKTKEQFGHMEPMVIHCNTGSGRTGVFIALSIVLDRLQQESVVDMYQTVKLLHKQRIGLVQTEEQYEFCYMAVLDYLSNYE 5814
++V L AN L E+ + D T S +N+ KNRY N+ A+DH VLL P++ SDYINANY+DGY++Q YIA QGPLP+T DFWRMVWEQ S IVM+T EER IKCHQYWP+ G YG + V+ + T L+ YTIR F ++ S E+R + + +TAWPDHGVP T +L F+R+ ++ E P +VHCSAGVGRTG ++V+DAQL+RI+ E +DV+NYV +R QRN MVQ + QY I + LLEA+ G+TE+ A + + +L + S + + EF +L+ R+ + F A N VN KNR N++PY+ RV L EGSDYINA+YIDGY ++A+IA Q+PIP T+ DFWRM+W+Q C +++L+Q E K H YWP + VV+ + + +YI+REFKVT+ ++ R +RQ+QFT WP+ G P ++D I QV + +++ G ++ +HC+ G GRTGVF A+SI+++RL+ E++VD++QTVK L +QR +VQT+EQYEFCY + +YL +++
Sbjct: 8 EHVRRLHANGELLFSQEYGAFRS--PDTVTSHHSLNQANRFKNRYNNITAFDHCRVLLQPIEGDPTSDYINANYLDGYRKQREYIAAQGPLPETCHDFWRMVWEQNSRVIVMVTNCEERGRIKCHQYWPSSGSQNYGVIHVNMMSTVELSDYTIRSFGVKRSGSPEERMVLQYHYTAWPDHGVPNSVTSVLNFVRKSSAVNLTEDYGPMVVHCSAGVGRTGTYVVIDAQLKRIQAEATVDVYNYVMMLRGQRNLMVQVEDQYVLIHDVLLEAIACGDTEIQARDLRQRIKEL--MRPSTDTGQTEMDAEFQRLS-------RNKAPPSKFQSA--NLPVNKHKNRYANVLPYDDTRVRLTMQAVTEGSDYINANYIDGYMSKKAFIATQAPIPDTIPDFWRMIWEQDCCTIVMLSQEMESGKVKVHRYWPGKQPTSIGNLVVEMLHDKQFDDYIMREFKVTNTKESASRVVRQYQFTAWPDIGSPDSGGGLIDLIGQVQRWQQKCG-VQLTAVHCSAGVGRTGVFCAVSILIERLKAEAMVDVFQTVKQLREQRPAMVQTKEQYEFCYQTLGEYLHSFD 572
BLAST of Protein tyrosine phosphatase receptor type D vs. Ensembl Nematostella
Match: EDO48187 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RK45]) HSP 1 Score: 472.241 bits (1214), Expect = 1.254e-148 Identity = 242/588 (41.16%), Postives = 354/588 (60.20%), Query Frame = 1
Query: 4069 ISICNLYQYVTDLKANDCTLLQAEFETLNTNLDDRFTWQRSNIDSNKSKNRYANVVAYDHTSVLLTPVDDVIGSDYINANYIDGYQRQNAYIATQGPLPDTTDDFWRMVWEQRSNCIVMMTRLEERSGIKCHQYWPNRGFICYGQMIVSHIDTFVLAYYTIRLFEIRHSKYSEKREIQHFQFTAWPDHGVPKLSTPLLMFIRRVRSIGKIESCPKIVHCSAGVGRTGAFIVVDAQLERIKQEKNIDVFNYVSKIRCQRNYMVQTQAQYQFILETLLEAVEDGNTEVMACNFHAHVTKLSQIGISGSNQLSGFEMEFSKLNSLASNRGRHGVMLADFVKAAGNQAVNMTKNRVRNIIPYEWNRVVLNAIRGIEGSDYINASYIDGYRDRRAYIAAQSPIPSTVEDFWRMLWDQHCGVVIVLNQPHED---KSHIYWPINKSIRYQFFVVDPVVEYNMPNYILREFKVTDARDGEFRALRQFQFTQWPNHGCPKESES---ILDFIRQVHKTKEQFGHMEPMVIHCNTGSGRTGVFIALSIVLDRLQQESVVDMYQTVKLLHKQRIGLVQTEEQYEFCYMAVLDYLSNYE 5814
ISI + Q+V ++ + E+E + + + T S N+ KNRY N+VAYDH+ V L +D GSDYINAN++ GY+R NAYIA QGPL +T DFWRMVWEQ S I+M+T L+ER KC QYWP+RG + Y + V+ L Y +R ++ + R+++ F FT+WPDHGVP LL F+R + P +VHCSAGVGRTG FIV+D L++I +EK +D+ +VS +R RN MVQT+ QY FI + LL+A+ G TE A + +H+ +L + + SG+ F++ L+ + + A VN KNR N++PY+ RV L+ G+EGSDYINA+YIDGY +R +IA Q+PIP T+ DFWRM+W+Q+C ++ L Q E K H YWP + I + VV+ + + ++R FK+T+ R +RQF +T W ++ S ++D I QV + + G P+++HC+ G GRTGVF A+SI+++RL+ E++VD++QTVK L +QR +VQT+ QY+FCY VL+YL+++E
Sbjct: 1 ISIDDFEQHVARMRRSGDLFFTTEYERIP--VPEHVTATHSLDPVNQHKNRYINIVAYDHSRVKLQDFEDEPGSDYINANFLPGYRRDNAYIAAQGPLAETCRDFWRMVWEQNSRTIIMLTNLKERCRDKCAQYWPSRGSLSYEDITVTLDSVTELTPYIVRTLSVQREGCDDVRQVKQFHFTSWPDHGVPTSVCNLLAFVRDSTRADPPGAGPMVVHCSAGVGRTGTFIVIDVMLQQIHEEKTVDILGFVSTLRRHRNLMVQTEQQYIFIHDALLDAIISGETETSASDLRSHIRRLQE-----QDPESGYTPMFTEFQKLSR------CINSSLSLNAATHPVNKRKNRYANVLPYDVTRVRLSMQVGVEGSDYINANYIDGYMAKRTFIATQAPIPETIPDFWRMVWEQNCCTIVTLAQEVEQAKAKMHRYWPGKQPITFGSLVVEMQDKVKSGHLVVRIFKLTNTEVSASRDVRQFHYTSWTEENPLEDGLSRCQLIDLIGQVQYWQAESGR-HPIIVHCSAGVGRTGVFCAVSILIERLKAEAMVDVFQTVKQLREQRPAMVQTKGQYDFCYQVVLEYLASFE 574 HSP 2 Score: 179.489 bits (454), Expect = 3.288e-47 Identity = 100/251 (39.84%), Postives = 140/251 (55.78%), Query Frame = 1
Query: 5101 VNMTKNRVRNIIPYEWNRVVLNAIRGIEGSDYINASYIDGYRDRRAYIAAQSPIPSTVEDFWRMLWDQHCGVVIVLNQPHE---DKSHIYWPINKSIRYQFFVV--DPVVEYNMPNYILREFKVTDARDGEFRALRQFQFTQWPNHGCPKESESILDFIRQVHKTKEQFGHMEPMVIHCNTGSGRTGVFIALSIVLDRLQQESVVDMYQTVKLLHKQRIGLVQTEEQYEFCYMAVLDYLSNYEKILEKSHL 5838
VN KNR NI+ Y+ +RV L GSDYINA+++ GYR AYIAAQ P+ T DFWRM+W+Q+ +I+L E DK YWP S+ Y+ V D V E + YI+R V + R ++QF FT WP+HG P ++L F+R T+ PMV+HC+ G GRTG FI + ++L ++ +E VD+ V L + R +VQTE+QY F + A+LD + + E S L
Sbjct: 43 VNQHKNRYINIVAYDHSRVKLQDFEDEPGSDYINANFLPGYRRDNAYIAAQGPLAETCRDFWRMVWEQNSRTIIMLTNLKERCRDKCAQYWPSRGSLSYEDITVTLDSVTE--LTPYIVRTLSVQREGCDDVRQVKQFHFTSWPDHGVPTSVCNLLAFVRD--STRADPPGAGPMVVHCSAGVGRTGTFIVIDVMLQQIHEEKTVDILGFVSTLRRHRNLMVQTEQQYIFIHDALLDAIISGETETSASDL 289
BLAST of Protein tyrosine phosphatase receptor type D vs. Ensembl Nematostella
Match: EDO31736 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SX30]) HSP 1 Score: 435.261 bits (1118), Expect = 2.709e-135 Identity = 229/584 (39.21%), Postives = 350/584 (59.93%), Query Frame = 1
Query: 4069 ISICNLYQYVTDLKANDCTLLQAEFETLNTNLDDRFTWQRSNIDSNKSKNRYANVVAYDHTSVLLTPVDDVIGSDYINANYIDGYQ-RQNAYIATQGPLPDTTDDFWRMVWEQRSNCIVMMTRLEERSGIKCHQYWPNRGFICYGQMIVSHIDTFVLAYYTIRLFEIRHSKYSEKREIQHFQFTAWPDHGVPKLSTPLLMFIRRVRSIGKIESCPKIVHCSAGVGRTGAFIVVDAQLERIKQEKNIDVFNYVSKIRCQRNYMVQTQAQYQFILETLLEAVEDGNTEVMACNFHAHVTKLSQIGISGSNQLSGFEMEFSKLNSLASNRGRHGVMLADFVKAAGNQAVNMTKNRVRNIIPYEWNRVVLNAIRGIEGSDYINASYIDGYRDRRAYIAAQSPIPSTVEDFWRMLWDQHCGVVIVLNQPHE-DKSHI-YWPINKSIRYQFFVVDPVVEYNMPNYILREFKVTDARDGEFRALRQFQFTQWPNHGCPKESESILDFIRQVHKTKEQFGHMEPMVIHCNTGSGRTGVFIALSIVLDRLQQESVVDMYQTVKLLHKQRIGLVQTEEQYEFCYMAVLDYLSNY 5811
I I +YV ++AN L+ E++ + +F W+ + +NK+KNRYAN+VAYDH+ V+L V+ SDYINA++I GY ++IA+QGPLP +DFWRMVWEQ S IVM+T L E KCH+YWP++ YG + V+ + + A Y IR F + +K S R ++ F FT WPD GVP+ +T +L F R+VR++ ++ P IVHCSAGVGRTGA+IV+DA LE+ K+ + +D+ NY+ +R R +MVQT+ QY FI +LEA+ GNTE+ + N + + KL+ ++ Q++G+ +EF K ++ G+ F A + N KNR NI+ Y+ +R+VL + G E SDYINAS+I +R R A+IA Q P+ TVEDFWRM+ D G +++LN HE D+ + YWP + +Y V + + + I + KVT + +R WP+ P+ + S+LD + + +++Q G+ P+++ C+ G GR+G F A+S VL+RL+ E V+D++Q +K + G V++ QY FCY + YL ++
Sbjct: 2 IPIALFPEYVAKMQANGGIRLETEYKKFDNG--QQFPWEAARKPANKNKNRYANIVAYDHSRVVLERVNGDEDSDYINASFIHGYDGTPRSFIASQGPLPPAFEDFWRMVWEQNSQSIVMLTNLVELGKTKCHKYWPDKTET-YGGVTVTLHQSEIFAEYEIRTFILSKAKQSGSRMVRQFHFTVWPDKGVPQYATAVLAFRRKVRALNPRDAGPVIVHCSAGVGRTGAYIVIDAMLEQAKKSRTVDIRNYLIALRKDRPHMVQTKEQYSFIHSAVLEALTCGNTEIQSENCNQAMQKLA--SVNRKFQMTGYALEFQKFDN-----GQQ------FPWEAARKPANKNKNRYANIVAYDHSRLVLERVNGNEDSDYINASFIHAHRGRNAFIATQHPLLETVEDFWRMVTDYDIGTIVMLNNLHELDQEYPKYWPDHGPTKYGHIGVSVLSKQEQGDVICTKLKVTRKKVRRTHEVRHLHHVSWPDKCIPEVACSVLDLLDEAQTSQQQCGNA-PVLVQCSNGVGRSGTFCAISSVLERLKTEQVIDVFQVIKRIRVNLPGAVESPTQYMFCYQIIQKYLDSF 568
BLAST of Protein tyrosine phosphatase receptor type D vs. Ensembl Medaka
Match: PTPRD (receptor-type tyrosine-protein phosphatase delta [Source:NCBI gene;Acc:101165843]) HSP 1 Score: 714.146 bits (1842), Expect = 0.000e+0 Identity = 333/606 (54.95%), Postives = 437/606 (72.11%), Query Frame = 1
Query: 4006 SDSIKLRIGSQKSENISDRPSISICNLYQYVTDLKANDCTLLQAEFETLNTNLDDRFTWQRSNIDSNKSKNRYANVVAYDHTSVLLTPVDDVIGSDYINANYIDGYQRQNAYIATQGPLPDTTDDFWRMVWEQRSNCIVMMTRLEERSGIKCHQYWPNRGFICYGQMIVSHIDTFVLAYYTIRLFEIRHSKYSEKREIQHFQFTAWPDHGVPKLSTPLLMFIRRVRSIGKIESCPKIVHCSAGVGRTGAFIVVDAQLERIKQEKNIDVFNYVSKIRCQRNYMVQTQAQYQFILETLLEAVEDGNTEVMACNFHAHVTKLSQIGISGSNQLSGFEMEFSKLNSLASNRGRHGVMLADFVKAAGNQAVNMTKNRVRNIIPYEWNRVVLNAIRGIEGSDYINASYIDGYRDRRAYIAAQSPIPSTVEDFWRMLWDQHCGVVIVLNQPHE---DKSHIYWPINKSIRYQFFVVDPVVEYNMPNYILREFKVTDARDGEFRALRQFQFTQWPNHGCPKESESILDFIRQVHKTKEQFGHMEPMVIHCNTGSGRTGVFIALSIVLDRLQQESVVDMYQTVKLLHKQRIGLVQTEEQYEFCYMAVLDYLSNYE 5814
+D ++LR + ++ +++ P I I L ++ LKAND E+E+++ +FTW+ SN++ NK KNRYANV+AYDH+ +LL+ +D + GSDYINANYIDGY++QNAYIATQGPLP+T +FWRM+WEQRS +VMMT+LEERS +KC QYWP RG YG + VS +DT LA Y +R F + + SEKRE++ FQFTAWPDHGVP+ TP L F+RRV++ ++ P +VHCSAGVGRTG FIV+DA LER K EK +D++ +V+ +R QRNYMVQT+ QY FI + LLEAV G TEV A N +A++ KL+Q I G ++G E+EF +L + ++ R F+ A N N KNR+ NI+PYE RV L IRG+EGSDYINAS+IDGYR ++AYIA Q P+ T EDFWRMLW+ + +V++L + E +K H YWP +S RYQ+FVVDP+ EYNMP YILREFKVTDARDG+ R +RQFQFT WP G PK E +DFI QVHKTKEQFG P+ +HC+ G GRTGVFI LSIVL+R++ E VVD++QTVK+L QR +VQTE+QY+FCY A L+YL +++
Sbjct: 1325 TDPVELRRLNFQTPGMANHPPIPISELADHLERLKANDNLKFSQEYESIDPA--QQFTWEHSNLEVNKPKNRYANVIAYDHSRILLSAIDGIPGSDYINANYIDGYRKQNAYIATQGPLPETFGEFWRMIWEQRSAVVVMMTKLEERSRVKCDQYWPTRGTETYGLIQVSLLDTVELATYCVRTFSLFKNGSSEKREVRQFQFTAWPDHGVPEHPTPFLAFLRRVKACNPPDAGPMVVHCSAGVGRTGCFIVIDAMLERNKHEKTVDIYGHVTLMRAQRNYMVQTEDQYVFIHDALLEAVNCGTTEVPARNLYAYIQKLTQ--IEGGENVTGMELEFKRLANTKAHTSR-------FISA--NLPCNKFKNRLVNIMPYESTRVCLQPIRGVEGSDYINASFIDGYRQQKAYIATQGPLAETTEDFWRMLWEHNSTIVVMLTKLREMGREKCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDARDGQSRTVRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKEQFGQDGPISVHCSAGVGRTGVFITLSIVLERMRYEGVVDIFQTVKMLRTQRPAMVQTEDQYQFCYRAGLEYLGSFD 1917 HSP 2 Score: 207.608 bits (527), Expect = 4.069e-53 Identity = 106/262 (40.46%), Postives = 154/262 (58.78%), Query Frame = 1
Query: 5092 NQAVNMTKNRVRNIIPYEWNRVVLNAIRGIEGSDYINASYIDGYRDRRAYIAAQSPIPSTVEDFWRMLWDQHCGVVIVLNQPHEDKSHI----YWPINKSIRYQFFVVDPVVEYNMPNYILREFKVTDARDGEFRALRQFQFTQWPNHGCPKESESILDFIRQVHKTKEQFGHMEPMVIHCNTGSGRTGVFIALSIVLDRLQQESVVDMYQTVKLLHKQRIGLVQTEEQYEFCYMAVLDYLSNYEKILEKSHLY*TYQDLSE 5865
N VN KNR N+I Y+ +R++L+AI GI GSDYINA+YIDGYR + AYIA Q P+P T +FWRM+W+Q VV+++ + E++S + YWP + Y V + + Y +R F + E R +RQFQFT WP+HG P+ L F+R+V PMV+HC+ G GRTG FI + +L+R + E VD+Y V L+ QR +VQTE+QY F + A+L+ ++ + +LY Q L++
Sbjct: 1385 NLEVNKPKNRYANVIAYDHSRILLSAIDGIPGSDYINANYIDGYRKQNAYIATQGPLPETFGEFWRMIWEQRSAVVVMMTK-LEERSRVKCDQYWPTRGTETYGLIQVSLLDTVELATYCVRTFSLFKNGSSEKREVRQFQFTAWPDHGVPEHPTPFLAFLRRVKACNPP--DAGPMVVHCSAGVGRTGCFIVIDAMLERNKHEKTVDIYGHVTLMRAQRNYMVQTEDQYVFIHDALLEAVNCGTTEVPARNLYAYIQKLTQ 1643 HSP 3 Score: 130.568 bits (327), Expect = 1.104e-29 Identity = 195/887 (21.98%), Postives = 338/887 (38.11%), Query Frame = 1
Query: 313 PKISLIIQSPNVLLFKSMILACSSTGHPVPSISWKINESPIEELKSPLKKLQNPPRIFSIKNYQNSVLVITQLIESDSNSVLICEAENNAGFD-SRQQQLKVISTETDIPSGFPVFQNNFFPIIKPYNSNVTLVCQAYGNPPPLIQWFKNYELINESFTKIKILNDGNLLLVQVTREDKGIYHCQAQNTNGLRLSDPSTLDITSYPISPNSLIIERFASDNVEISWRSGLNDVTEQENFILHYREVPENITEKQIMSKFVYLTISEKK----SIYKYNLKDLFPFTTYCIWMESENPLGVSPPTIALTVKTLPTSPQLSPRSITATSISNTAILVAWRPPERKFGKFKYYQIIYTNNDGFLPQHWRQFAVKDDNVMLTH-LIASELYHIRVKIVNEIGHGPLSKTISIKTIAGTLSQCPDFKITEIFQSHIKLQWGTPDPV-KLFKLIQYNLLCWDVRLKIVNATAKSSTLFPILNHNLSMNEMEYVLYLKNEKEIKCRLSAINSDGKGMPT-EIQAST--VNKGVNYQNLIHIDKIGSTYITFQWRPPSKFSFDYFLWIYQI--FDSEKLDRAVKLPKIKINISDSASAENGWFVYNYTNAFSSSRYILGLRYLCRDSTDILREYVHRSDLVSTMKSVPSDSPKDLVVKEIDSNSALVSWKPLDQVHSNGIITHYEVRYYAPKKEESTER--------------FINVSETSAILSNL-KYFHYVIYVRAFTKVGGGSWSNPKNYYRQN-LEEFP---IPTTIKGERKSETEINISWELPVLSEKNLAHAAIEGFIILYAPVESSPKWIKYTVQSKNLSAVIKGLEPDLRYQFQIAATNYAGFN-GNFSEIV--QEMPKNFPNLNLKTVPDLRCSVQSSNRLKVEW 2871
P I + Q V ++ + C+++G+P P ISW + P+ + + IK ++ L I Q ESD C A NN G S L V P N P +V + C A G+P P ++W L E T + G +L + Y C A +T G+ + + + + + P +P ++ + ++ ++W SG PE +T I K Y K+ + +Y++ L P++ Y + + N +G PP+ ++ KT +P +PR + +S T ++ W PE G+ Y++ YT + W + V+ N + H LI ++ Y+I+V +G GPLS + I G SQ DFK ++ + L W TP + ++ Y L + K + K + P + L LK RL+A + G G T EI A T + + ST I WR P + + Y + +E D A + IS+ + + + N R TD+ L+ T + VPS P+ + V+ ++S+S V W+ +G I Y+V Y E T + F + +E I++ L Y + V A+T G G+ S PK + E P + TT G + W P ++ H ++G+ + + + P + Q ++ + Y F+++A N GF EI +++P +P +++ +++ ++V W
Sbjct: 142 PTIDMGPQLKVVERTRTATMLCAASGNPDPDISWFKDFLPVNTSNNNGR----------IKQLRSGALQIEQSEESDQGKYE-CVATNNDGTRYSAPANLYVRVRRVPPRFSIPPTDNEIMP-----GGSVNITCVAVGSPMPYVKWM----LGAEDLTPEDDMPIGRNVLELTDVQQSANYTCVAMSTLGV-IEAVAQITVKALPKAPGIPVVTERTATSITLTWDSG----------------NPEPVTYYIIQHKSKYSDDLYKEINGVATTRYSVGGLSPYSDYEFRVVAVNNIGRGPPSESIEAKTAEQAPSTAPRHVRGHMMSATTAVIQWDEPEEANGQIMGYRVYYTMDPTQHVNIWEKQIVRGSNFVTIHGLIPNKTYNIKVLAYTSVGDGPLSPDLQIIAKTGVPSQPTDFKGEAKSETSVLLSWNTPSQTGQENQVTGYEL----IYRKRDDKEEKQISFEPTTTYLLKD--------LKPFTTYTFRLAARSKHGVGAYTSEISAETPQTPEPAGPPEEVKCSSPSSTKILVSWRAPPVELRNGIITQYTVSYAPTEGEDTAAR------QISNIPPESSQYLLENLEKWTE-------YRVTVTAHTDVGAGPESLPHLIRTEEDVPSGPPRKVEVEAVNSSSIKVIWRSPVPTKQHGQIRGYQVHYVRMVNGEPTGQPVIKDILIDDAQWEFEDSTEHEMIITGLMAETTYSVTVAAYTTKGDGARSKPKLITTTGAVPEKPRLMVSTTNMGTAL------LQWHPPAVT-----HGPLQGYRLRFGRKDVDPLTV-IEFQERDNHYTTSEIHKGASYTFRLSARNKVGFGEETVKEITTNEDVPSGYPQ-------NIKAEGATTSTIQVSW 947 HSP 4 Score: 123.25 bits (308), Expect = 1.952e-27 Identity = 187/786 (23.79%), Postives = 294/786 (37.40%), Query Frame = 1
Query: 376 CSSTGHPVPSISWKINESPIEELKSPLKKLQNPP-RIFSIKNYQNSVLVITQLIESDSNSVLICEAENNAGFDSRQQQLKVISTETDIPSGFPVFQNNFFPIIKPYNSNVTLVCQAYGNPPPLIQWFKNYELINESFT--KIKILNDGNLLLVQVTREDKGIYHCQAQNTNGLRLSDPSTLDI------TSYPISPNSLIIERFASDNVE----------ISWRSGLNDVTEQENFILHYREVPENITEKQIMSKFVYLTISEKKSIYKYNLKDLFPFTTYCIWMESENPLGVSPPTIALTVKTLPTSPQLSPRSITATSISNTAILVAW---RPPERKF----GKFKYYQIIYTNNDGFLPQHWRQFAVKDDNVMLTHLIASELYHIRVKIVNEIGHGPLSKTISIKTIAGTLSQCPDFKITEIFQSHIK-LQWGTPDPVKLFKLIQYNLLCWDVRLKIVN----ATAKSSTLFPILNHNLSMNEMEYVLYLKNEKEIKCRLSAINSDGKGMPTEIQASTVNKGVNYQNLIHIDKIGS-TYITFQWRPPSKFSFDYFLWIYQIFDSEKLDRAVKLPKIKINISDSASAENGWFVYNYTNAFSSSRYILGLRYLCRDSTDILREYVHRSDLVSTMKSVPSDSPKDLVVKEIDSNSALVSWKPLDQVHSNGIITHYEVRYYAPKKEESTERFI-NVSETSA--ILSNL-KYFHYVIYVRAFTKVGGGSWSNPKNYYRQNLEEFP--IPTTIKGERKSETEINISWELPVLSEKNLAHAAIEGFIILY 2619
C +TG P P I W KK+ N + + SVL I L ++ C A N G S +L V+ E +P GFP + T++C A GNP P I WFK++ +N S +IK L G L + Q D+G Y C A N +G R S P+ L + + I P I S N+ + W G D+T +++ + N+ E LT ++ + Y C+ M + LGV +TVK LP +P + T + T+I + W P + K KY +Y +G V + L Y RV VN IG GP S++I KT S P + + +QW P+ +++ Y + + VN + S I H L N K ++ A S G G + GV Q + S T + W PS+ + + Y++ ++ D+ K +I+ + + ++ F++ + L R S + Y + P+ P+++ S LVSW+ NGIIT Y V Y + E++ R I N+ S+ +L NL K+ Y + V A T VG G S P + + E+ P P ++ E + + I + W PV +++ H I G+ + Y
Sbjct: 61 CQATGDPRPKIVWNKKG----------KKVSNQRFEVIEFDDGSGSVLRIQPLRTPRDEAIYECVASNTVGEISASTRLTVLR-EDQLPPGFPTIDMGPQLKVVERTRTATMLCAASGNPDPDISWFKDFLPVNTSNNNGRIKQLRSGALQIEQSEESDQGKYECVATNNDGTRYSAPANLYVRVRRVPPRFSIPPTDNEIMPGGSVNITCVAVGSPMPYVKWMLGAEDLTPEDDM-----PIGRNVLE---------LTDVQQSANYT------------CVAMST---LGVIEAVAQITVKALPKAPGIP----VVTERTATSITLTWDSGNPEPVTYYIIQHKSKYSDDLYKEING----------VATTRYSVGGLSPYSDYEFRVVAVNNIGRGPPSESIEAKTAEQAPSTAPRHVRGHMMSATTAVIQWDEPEEAN-GQIMGYRVYYTMDPTQHVNIWEKQIVRGSNFVTI--HGLIPN-----------KTYNIKVLAYTSVGDGPLSPDLQIIAKTGVPSQPTDFKGEAKSETSVLLSWNTPSQTGQENQVTGYELIYRKRDDKEEK----QISFEPTTT-----YLLKDLKPFTTYTFRLAAR-----SKHGVGAYTSEISAETPQTPEPAGPPEEVKCSSPSSTKILVSWRAPPVELRNGIITQYTVSYAPTEGEDTAARQISNIPPESSQYLLENLEKWTEYRVTVTAHTDVGAGPESLP--HLIRTEEDVPSGPPRKVEVEAVNSSSIKVIWRSPVPTKQ---HGQIRGYQVHY 759 HSP 5 Score: 103.99 bits (258), Expect = 1.493e-21 Identity = 160/681 (23.49%), Postives = 269/681 (39.50%), Query Frame = 1
Query: 916 TSYPISPNSLIIERFASDNVEISWRSGLNDVTEQENFILHYREV---PENITEKQIMSKFVYLTISEKKSIYKYNLKDLFPFTTYCIWMESENPLGVSPPTIALTVKTLPT-SPQLSPRSITATSISNTAILVAWRPP--ERKFGKFKYYQIIYTNNDG--FLPQHWRQFAVKDDNVMLTHLIASELYHIRVKIVNEIGHGPLSKTISIKTIAGTLSQCP-DFKITEIFQSHIKLQWGTPDPVKLFKLIQYNLLCWDVRLKIVNATAKSSTLFPILNHNL---------SMNEMEYVLY-LKNEKEIKCRLSAINSDGKGMPTEIQASTVNKGVNYQNLIHIDKIGSTYITFQWRPPSKFSFDYFLWIYQI-FDSEKLDRAVKLPKIKINISDSASAENGWFVYNYTNAFSSSRYILGLRYLCRDSTDILREYVHRSDLVSTMKSVPSDSPKDLVVKEIDSNSALVSWKPLDQVHSNGIITHYEVRYYAPKKEES-TERFINVSETSAILSNLKY-FHYVIYVRAFTKVGGGSWSNPKNYYRQNLEEFPIPTTIKGERKSETEINISWELPVLSEKNLAHAAIEGFIILYAPVESSPKWIKYTVQSKNLSAVIKGLEPDLRYQFQIAATNYAGFNGNFSEIVQEMPKNFPNLNLKTVPDLRCSVQSSNRLKVEWSSPSIST 2892
T P P E + +V +SW + T QEN + Y + ++ EKQI F T Y LKDL PFTTY + + + GV T ++ +T T P P + +S S+T ILV+WR P E + G Y + Y +G + + +L +L Y + V ++G GP S I+T S P ++ + S IK+ W +P P K I+ + + +++VN T P++ L E E ++ L E ++A + G G ++ + T V + + + QW PP+ L Y++ F + +D L I+ D+ +YT + R R+ E V ++T + VPS P+++ + +++ VSW+P+ NG I Y ++Y S +E FI E++ +L L+ Y I + AFT G G +S + Q +++ ++ + ++WE+P + + F ILY +S V + +I GL+P+ +Y F + TN G V M P++ L+T P L S + VE P++ T
Sbjct: 516 TGVPSQPTDFKGEAKSETSVLLSWNTPSQ--TGQENQVTGYELIYRKRDDKEEKQI--SFEPTTT--------YLLKDLKPFTTYTFRLAARSKHGVGAYTSEISAETPQTPEPAGPPEEVKCSSPSSTKILVSWRAPPVELRNGIITQYTVSYAPTEGEDTAARQISNIPPESSQYLLENLEKWTEYRVTVTAHTDVGAGPESLPHLIRTEEDVPSGPPRKVEVEAVNSSSIKVIWRSPVPTKQHGQIRGYQVHY---VRMVNG---EPTGQPVIKDILIDDAQWEFEDSTEHEMIITGLMAETTYSVTVAAYTTKGDGARSKPKLITTTGAVPEKPRLMVSTTNMGTALLQWHPPAVTHGP--LQGYRLRFGRKDVD---PLTVIEFQERDN----------HYTTSEIHKGASYTFRLSARNKVGFGEETVKE---ITTNEDVPSGYPQNIKAEGATTSTIQVSWQPVLLAERNGKIVKYALQYKDINSPRSPSELFITAPESTVVLDGLRPDTTYDIKMCAFTSKGSGPYSPSVQFRTQPVDQAVFAKNFHVRAAMKSSVLLTWEIPD------TYNPAQPFTILYDKGQS------VEVDGRLTQKLITGLQPETQYSFLL--TNRGNSAGGLQHRVSTM--TAPDV-LRTKPYLIGKTNSDGMVTVEL--PTVQT 1141 HSP 6 Score: 65.855 bits (159), Expect = 5.111e-10 Identity = 86/355 (24.23%), Postives = 147/355 (41.41%), Query Frame = 1
Query: 2062 VYNYTNAFSSSRYILG-------LRYLCRDSTDILREYVHRSDLVSTMKSVPSDSPKDLVVKEIDSNSALVSWKPLDQVHSNGIITHYEVRYYAPKKEESTERFINVSETSAIL-SNLKYFH-------YVIYVRAFTKVGGGSWSNPKNYYRQNLEEFPIPTTIKGERKSETEINISWELPVLSEKNLAHAAIEGFIILYAPVESSPKWIKYTVQSKNLSAVIKGLEPDLRYQFQIAATNYAGFNGNFSEIVQEMPKNFPNLNLKTVPDLRCSVQSSNRLKVEWSSPSISTDLLKFEIRYSGNLSYITEIGLKKSEFIDMESKSV-NFETLVNRYDVTLENLQSNALYKIAVRA 3078
+Y N +++RY +G + +I R S T + PS +P+ + + + +A++ W ++ +NG I Y V Y + +N+ E + SN H Y I V A+T VG G S P PT KGE KSET + +SW P + + G+ ++Y + K K + ++K L+P Y F++AA + G SEI E P+ +++CS SS ++ V W +P + E+R +G ++ T + +E D ++ + N ++Y LENL+ Y++ V A
Sbjct: 369 LYKEINGVATTRYSVGGLSPYSDYEFRVVAVNNIGRGPPSESIEAKTAEQAPSTAPRHVRGHMMSATTAVIQWDEPEE--ANGQIMGYRVYYTM-----DPTQHVNIWEKQIVRGSNFVTIHGLIPNKTYNIKVLAYTSVGDGPLS-PDLQIIAKTGVPSQPTDFKGEAKSETSVLLSWNTP---SQTGQENQVTGYELIYR--KRDDKEEKQISFEPTTTYLLKDLKPFTTYTFRLAARSKHGVGAYTSEISAETPQTPEPAGPPE--EVKCSSPSSTKILVSWRAPPV-------ELR-NGIITQYT-VSYAPTEGEDTAARQISNIPPESSQY--LLENLEKWTEYRVTVTA 697 HSP 7 Score: 63.1586 bits (152), Expect = 3.200e-9 Identity = 192/883 (21.74%), Postives = 338/883 (38.28%), Query Frame = 1
Query: 1054 NITEKQIMSKFVYLTISEKKSIYKYNLKDLFPFTTYCIWMESENPLGVSP--PTIALTVKT-LPTSPQLSPRSITATSISNTAILVAWRPPER--KFGKFKYYQIIYTNNDGFLPQHWRQFAVKDDNV-MLTHLIASELYHIRVKIVNEIGHGPLSKTISIKTIAGTLSQCP--DFKITEIFQSHIKLQWGTPDPVKLFKLI--QYNLLCWDVRLKIVNATAKSSTLFPILNHNLSMNEMEYVLY-LKNEKEIKCRLSAINSDGKG---MPTEIQAST-VNKGVNYQNLIHIDKIGSTYITFQWRPPSKFSFDYFLWIYQIFDSEKLD-RAVKLPKIKINISDSASAENGWFVYNYTNAFSSSRYILGLRYLCRDSTDILREYVHRSD-------LVSTMKSVPSDSPKDLVVKEIDSNSALVSWKPLDQVHSNGIITHYEVRYYAPKKEESTERFINVSE------TSAILSNLKYFHYVIYVRAFTKVGGGSWSNPKNYYRQNLEEFPIPTTIKGERKSETEINISWELPVLSEKNLAHAAIEGFIILYAPVESSPKWIKYTVQSKNLSAVIKGLEPDLRYQFQIAATNYAGFNGNFSEIVQEMPKNFPNLNLKTVPDLRCSVQSSNRLKVEWSSPSISTDLLKFEIRYSGNLSYITEIGLKKSEFIDMESKSVNFETLVNRYDVTLENLQSNALYKIAVRAIYQNKELYESHRETTCDTMPAVPNLVKPPIIVGLDEEKSKVIIKLHRCSQRNGKISYYFVIVAAFQGNKNQQ-ISFQEDTESYTFMEL--SVNTRSNNAKGEYIAIMKD-INDIFKVSGKDHSSVLLGDGTHDENHLSVNKKLEKNFNYRCFARVCLKYSNNSLCKSSPWSEPFRISDL 3603
NI EKQI+ ++TI L P TY I + + +G P P + + KT +P+ P + S T++L++W P + + + Y++IY D + +Q + + +L L Y R+ ++ G G + IS +T P + K + + I + W P PV+L I QY + + A S N+ +Y+L L+ E + ++A G G +P I+ V G + + ++ + S+ I WR P + YQ+ ++ P IK + D A E + ++ I GL S + Y + D L++T +VP + P+ L+V + +AL+ W P H G + Y +R+ +K+ I E TS I K Y + A KVG G + + +++ P IK E + + I +SW+ +L+E+N I + + Y + S + + + + V+ GL PD Y ++ A G +G +S VQ + +R +++SS + + W P F I Y S + L + ++ ++ L NR + + LQ HR TM A L P ++G V ++L Q + +I Y+V+V + + + + ++ + EL +N S + + A K I FK K+ + LGDG + NK+L+ Y F L+ S N + +SP+S+ +D+
Sbjct: 467 NIWEKQIVRGSNFVTI-----------HGLIPNKTYNIKVLAYTSVGDGPLSPDLQIIAKTGVPSQPT----DFKGEAKSETSVLLSWNTPSQTGQENQVTGYELIYRKRDD---KEEKQISFEPTTTYLLKDLKPFTTYTFRLAARSKHGVGAYTSEISAETPQTPEPAGPPEEVKCSSPSSTKILVSWRAP-PVELRNGIITQYTVSYAPTEGEDTAARQIS---------NIPPESSQYLLENLEKWTEYRVTVTAHTDVGAGPESLPHLIRTEEDVPSGPPRK--VEVEAVNSSSIKVIWRSPVPTKQHGQIRGYQVHYVRMVNGEPTGQPVIKDILIDDAQWE-------FEDSTEHEMIITGLMAETTYSVTVA-AYTTKGDGARSKPKLITTTGAVP-EKPR-LMVSTTNMGTALLQWHPPAVTH--GPLQGYRLRFG--RKDVDPLTVIEFQERDNHYTTSEIH---KGASYTFRLSARNKVGFGEETVKEITTNEDVPSG-YPQNIKAEGATTSTIQVSWQPVLLAERN---GKIVKYALQYKDINSPRSPSELFITAPESTVVLDGLRPDTTYDIKMCAFTSKG-SGPYSPSVQFRTQPVDQAVFAKNFHVRAAMKSS--VLLTWEIPDTYNPAQPFTILYDKGQSVEVDGRLTQKLITGLQPETQYSFLLTNRGN-SAGGLQ---------------------HR---VSTMTAPDVLRTKPYLIGKTNSDGMVTVELPTV-QTSERIRGYYVVVVPLKKQRTGKFLKPWDNPDEMNLEELLKEINRTSRGLRFQRHAEPKAYIAAYFKDLPKEFT---LGDGKIYGDF--ENKQLQNGQEYVFFVLAVLEMSENIMYATSPYSDSVISADI 1264
BLAST of Protein tyrosine phosphatase receptor type D vs. Ensembl Medaka
Match: PTPRD (receptor-type tyrosine-protein phosphatase delta [Source:NCBI gene;Acc:101165843]) HSP 1 Score: 713.375 bits (1840), Expect = 0.000e+0 Identity = 333/606 (54.95%), Postives = 437/606 (72.11%), Query Frame = 1
Query: 4006 SDSIKLRIGSQKSENISDRPSISICNLYQYVTDLKANDCTLLQAEFETLNTNLDDRFTWQRSNIDSNKSKNRYANVVAYDHTSVLLTPVDDVIGSDYINANYIDGYQRQNAYIATQGPLPDTTDDFWRMVWEQRSNCIVMMTRLEERSGIKCHQYWPNRGFICYGQMIVSHIDTFVLAYYTIRLFEIRHSKYSEKREIQHFQFTAWPDHGVPKLSTPLLMFIRRVRSIGKIESCPKIVHCSAGVGRTGAFIVVDAQLERIKQEKNIDVFNYVSKIRCQRNYMVQTQAQYQFILETLLEAVEDGNTEVMACNFHAHVTKLSQIGISGSNQLSGFEMEFSKLNSLASNRGRHGVMLADFVKAAGNQAVNMTKNRVRNIIPYEWNRVVLNAIRGIEGSDYINASYIDGYRDRRAYIAAQSPIPSTVEDFWRMLWDQHCGVVIVLNQPHE---DKSHIYWPINKSIRYQFFVVDPVVEYNMPNYILREFKVTDARDGEFRALRQFQFTQWPNHGCPKESESILDFIRQVHKTKEQFGHMEPMVIHCNTGSGRTGVFIALSIVLDRLQQESVVDMYQTVKLLHKQRIGLVQTEEQYEFCYMAVLDYLSNYE 5814
+D ++LR + ++ +++ P I I L ++ LKAND E+E+++ +FTW+ SN++ NK KNRYANV+AYDH+ +LL+ +D + GSDYINANYIDGY++QNAYIATQGPLP+T +FWRM+WEQRS +VMMT+LEERS +KC QYWP RG YG + VS +DT LA Y +R F + + SEKRE++ FQFTAWPDHGVP+ TP L F+RRV++ ++ P +VHCSAGVGRTG FIV+DA LER K EK +D++ +V+ +R QRNYMVQT+ QY FI + LLEAV G TEV A N +A++ KL+Q I G ++G E+EF +L + ++ R F+ A N N KNR+ NI+PYE RV L IRG+EGSDYINAS+IDGYR ++AYIA Q P+ T EDFWRMLW+ + +V++L + E +K H YWP +S RYQ+FVVDP+ EYNMP YILREFKVTDARDG+ R +RQFQFT WP G PK E +DFI QVHKTKEQFG P+ +HC+ G GRTGVFI LSIVL+R++ E VVD++QTVK+L QR +VQTE+QY+FCY A L+YL +++
Sbjct: 1186 TDPVELRRLNFQTPGMANHPPIPISELADHLERLKANDNLKFSQEYESIDPA--QQFTWEHSNLEVNKPKNRYANVIAYDHSRILLSAIDGIPGSDYINANYIDGYRKQNAYIATQGPLPETFGEFWRMIWEQRSAVVVMMTKLEERSRVKCDQYWPTRGTETYGLIQVSLLDTVELATYCVRTFSLFKNGSSEKREVRQFQFTAWPDHGVPEHPTPFLAFLRRVKACNPPDAGPMVVHCSAGVGRTGCFIVIDAMLERNKHEKTVDIYGHVTLMRAQRNYMVQTEDQYVFIHDALLEAVNCGTTEVPARNLYAYIQKLTQ--IEGGENVTGMELEFKRLANTKAHTSR-------FISA--NLPCNKFKNRLVNIMPYESTRVCLQPIRGVEGSDYINASFIDGYRQQKAYIATQGPLAETTEDFWRMLWEHNSTIVVMLTKLREMGREKCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDARDGQSRTVRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKEQFGQDGPISVHCSAGVGRTGVFITLSIVLERMRYEGVVDIFQTVKMLRTQRPAMVQTEDQYQFCYRAGLEYLGSFD 1778 HSP 2 Score: 207.608 bits (527), Expect = 3.662e-53 Identity = 106/262 (40.46%), Postives = 154/262 (58.78%), Query Frame = 1
Query: 5092 NQAVNMTKNRVRNIIPYEWNRVVLNAIRGIEGSDYINASYIDGYRDRRAYIAAQSPIPSTVEDFWRMLWDQHCGVVIVLNQPHEDKSHI----YWPINKSIRYQFFVVDPVVEYNMPNYILREFKVTDARDGEFRALRQFQFTQWPNHGCPKESESILDFIRQVHKTKEQFGHMEPMVIHCNTGSGRTGVFIALSIVLDRLQQESVVDMYQTVKLLHKQRIGLVQTEEQYEFCYMAVLDYLSNYEKILEKSHLY*TYQDLSE 5865
N VN KNR N+I Y+ +R++L+AI GI GSDYINA+YIDGYR + AYIA Q P+P T +FWRM+W+Q VV+++ + E++S + YWP + Y V + + Y +R F + E R +RQFQFT WP+HG P+ L F+R+V PMV+HC+ G GRTG FI + +L+R + E VD+Y V L+ QR +VQTE+QY F + A+L+ ++ + +LY Q L++
Sbjct: 1246 NLEVNKPKNRYANVIAYDHSRILLSAIDGIPGSDYINANYIDGYRKQNAYIATQGPLPETFGEFWRMIWEQRSAVVVMMTK-LEERSRVKCDQYWPTRGTETYGLIQVSLLDTVELATYCVRTFSLFKNGSSEKREVRQFQFTAWPDHGVPEHPTPFLAFLRRVKACNPP--DAGPMVVHCSAGVGRTGCFIVIDAMLERNKHEKTVDIYGHVTLMRAQRNYMVQTEDQYVFIHDALLEAVNCGTTEVPARNLYAYIQKLTQ 1504 HSP 3 Score: 140.584 bits (353), Expect = 9.944e-33 Identity = 255/1118 (22.81%), Postives = 432/1118 (38.64%), Query Frame = 1
Query: 313 PKISLIIQSPNVLLFKSMILACSSTGHPVPSISWKINESPIEELKSPLKKLQNPPRIFSIKNYQNSVLVITQLIESDSNSVLICEAENNAGFD-SRQQQLKVISTETDIPSGFPVFQNNFFPIIKPYNSNVTLVCQAYGNPPPLIQWFKNYELINESFTKIKILNDGNLLLVQVTREDKGIYHCQAQNTNGLRLSDPSTLDITSYPISPNSLIIERFASDNVEISWRSGLNDVTEQENFILHYREVPENITEKQIMSKFVYLTISEKK----SIYKYNLKDLFPFTTYCIWMESENPLGVSPPTIALTVKTLPTSPQLSPRSITATSISNTAILVAWRPPERKFGKFKYYQIIYTNNDGFLPQHWRQFAVKDDNVMLTH-LIASELYHIRVKIVNEIGHGPLSKTISIKTIAGTLSQCPDFKITEIFQSHIKLQWGTPDPV-KLFKLIQYNLLCWDVRLKIVNATAKSSTLFPILNHNLSMNEMEYVLYLKNEKEIKCRLSAINSDGKGMPT-EIQASTV-NKGVNYQNLIHIDKIGSTYITFQWRPPSKFSFDYFLWIYQI--FDSEKLDRAVKLPKIKINISDSASAENGWFVYNYTNAFSSSRYILGLRYLCRDSTDILREYVHRSDLVSTMKSVPSDSPKDLVVKEIDSNSALVSWKPLDQVHSNGIITHYEVRYYAPKKEESTERFINVSE------TSAILSNLKYFHYVIYVRAFTKVGGGSWSNPKNYYRQNLEEFPIPTTIKGERKSETEINISWELPVLSEKNLAHAAIEGFIILYAPVESSPKWIKYTVQSKNLSAVIKGLEPDLRYQFQIAATNYAGFNGNFSEIVQEMPKNFPNLNLKTVPDLRCSVQSSNRLKVEWSSPSISTDLLKFEIRYSGNLSYITEIGLKKSEFIDMESKSVNFETLVNRYDVTLENLQSNALYKIAVRAIYQNKELYESHRETTCDTMPAVPNLVKPPIIVGLDEEKSKVIIKLHRCSQRNGKISYYFVIVAAFQGNKNQQ-ISFQEDTESYTFMEL--SVNTRSNNAKGEYIAIMKD-INDIFKVSGKDHSSVLLGDGTHDENHLSVNKKLEKNFNYRCFARVCLKYSNNSLCKSSPWSEPFRISDL 3603
P I + Q V ++ + C+++G+P P ISW + P+ + + IK ++ L I Q ESD C A NN G S L V P N P +V + C A G+P P ++W L E T + G +L + Y C A +T G+ + + + + + P +P ++ + ++ ++W SG PE +T I K Y K+ + +Y++ L P++ Y + + N +G PP+ ++ KT +P +PR + +S T ++ W PE G+ Y++ YT + W + V+ N + H LI ++ Y+I+V +G GPLS + I G SQ DFK ++ + L W TP + ++ Y L + K + K + P + L LK RL+A + G G T EI A T + + ST I WR P + + Y + +E D A + +I NI +S Y N + Y R TD+ L+ T + VP + P+ L+V + +AL+ W P H G + Y +R+ +K+ I E TS I K Y + A KVG G + + +++ P IK E + + I +SW+ +L+E+N I + + Y + S + + + + V+ GL PD Y ++ A G +G +S VQ + + K +R +++SS + + W P F I Y S + L + ++ ++ L NR + + LQ HR TM A L P ++G V ++L Q + +I Y+V+V + + + + ++ + EL +N S + + A K I FK K+ + LGDG + NK+L+ Y F L+ S N + +SP+S+ +D+
Sbjct: 118 PTIDMGPQLKVVERTRTATMLCAASGNPDPDISWFKDFLPVNTSNNNGR----------IKQLRSGALQIEQSEESDQGKYE-CVATNNDGTRYSAPANLYVRVRRVPPRFSIPPTDNEIMP-----GGSVNITCVAVGSPMPYVKWM----LGAEDLTPEDDMPIGRNVLELTDVQQSANYTCVAMSTLGV-IEAVAQITVKALPKAPGIPVVTERTATSITLTWDSG----------------NPEPVTYYIIQHKSKYSDDLYKEINGVATTRYSVGGLSPYSDYEFRVVAVNNIGRGPPSESIEAKTAEQAPSTAPRHVRGHMMSATTAVIQWDEPEEANGQIMGYRVYYTMDPTQHVNIWEKQIVRGSNFVTIHGLIPNKTYNIKVLAYTSVGDGPLSPDLQIIAKTGVPSQPTDFKGEAKSETSVLLSWNTPSQTGQENQVTGYEL----IYRKRDDKEEKQISFEPTTTYLLKD--------LKPFTTYTFRLAARSKHGVGAYTSEISAETPQTQPAGPPEEVKCSSPSSTKILVSWRAPPVELRNGIITQYTVSYAPTEGEDTAAR--QIS-NIPPESSQ------YLLENLEKWTEY----RVTVTAHTDVGAGPESLPHLIRTEEDVP-EKPR-LMVSTTNMGTALLQWHPPAVTH--GPLQGYRLRFG--RKDVDPLTVIEFQERDNHYTTSEI---HKGASYTFRLSARNKVGFGEETVKEITTNEDVPSG-YPQNIKAEGATTSTIQVSWQPVLLAERN---GKIVKYALQYKDINSPRSPSELFITAPESTVVLDGLRPDTTYDIKMCAFTSKG-SGPYSPSVQFRTQPVDQVFAKNF-HVRAAMKSS--VLLTWEIPDTYNPAQPFTILYDKGQSVEVDGRLTQKLITGLQPETQYSFLLTNRGN-SAGGLQ---------------------HR---VSTMTAPDVLRTKPYLIGKTNSDGMVTVELPTV-QTSERIRGYYVVVVPLKKQRTGKFLKPWDNPDEMNLEELLKEINRTSRGLRFQRHAEPKAYIAAYFKDLPKEFT---LGDGKIYGDF--ENKQLQNGQEYVFFVLAVLEMSENIMYATSPYSDSVISADI 1125 HSP 4 Score: 97.0561 bits (240), Expect = 1.820e-19 Identity = 112/439 (25.51%), Postives = 163/439 (37.13%), Query Frame = 1
Query: 376 CSSTGHPVPSISWKINESPIEELKSPLKKLQNPP-RIFSIKNYQNSVLVITQLIESDSNSVLICEAENNAGFDSRQQQLKVISTETDIPSGFPVFQNNFFPIIKPYNSNVTLVCQAYGNPPPLIQWFKNYELINESFT--KIKILNDGNLLLVQVTREDKGIYHCQAQNTNGLRLSDPSTLDI------TSYPISPNSLIIERFASDNVE----------ISWRSGLNDVTEQENFILHYREVPENITEKQIMSKFVYLTISEKKSIYKYNLKDLFPFTTYCIWMESENPLGVSPPTIALTVKTLPTSPQLSPRSITATSISNTAILVAW---RPPERKF----GKFKYYQIIYTNNDGFLPQHWRQFAVKDDNVMLTHLIASELYHIRVKIVNEIGHGPLSKTISIKTIAGTLSQCPDFKITEIFQSHIK-LQWGTPD 1611
C +TG P P I W KK+ N + + SVL I L ++ C A N G S +L V+ E +P GFP + T++C A GNP P I WFK++ +N S +IK L G L + Q D+G Y C A N +G R S P+ L + + I P I S N+ + W G D+T +++ + N+ E LT ++ + Y C+ M + LGV +TVK LP +P + T + T+I + W P + K KY +Y +G V + L Y RV VN IG GP S++I KT S P + + +QW P+
Sbjct: 37 CQATGDPRPKIVWNKKG----------KKVSNQRFEVIEFDDGSGSVLRIQPLRTPRDEAIYECVASNTVGEISASTRLTVLR-EDQLPPGFPTIDMGPQLKVVERTRTATMLCAASGNPDPDISWFKDFLPVNTSNNNGRIKQLRSGALQIEQSEESDQGKYECVATNNDGTRYSAPANLYVRVRRVPPRFSIPPTDNEIMPGGSVNITCVAVGSPMPYVKWMLGAEDLTPEDDM-----PIGRNVLE---------LTDVQQSANYT------------CVAMST---LGVIEAVAQITVKALPKAPGIP----VVTERTATSITLTWDSGNPEPVTYYIIQHKSKYSDDLYKEING----------VATTRYSVGGLSPYSDYEFRVVAVNNIGRGPPSESIEAKTAEQAPSTAPRHVRGHMMSATTAVIQWDEPE 421
BLAST of Protein tyrosine phosphatase receptor type D vs. Ensembl Medaka
Match: ptprsa (receptor-type tyrosine-protein phosphatase S [Source:NCBI gene;Acc:101174175]) HSP 1 Score: 712.605 bits (1838), Expect = 0.000e+0 Identity = 330/612 (53.92%), Postives = 440/612 (71.90%), Query Frame = 1
Query: 3988 LSPVLVSDSIKLRIGSQKSENISDRPSISICNLYQYVTDLKANDCTLLQAEFETLNTNLDDRFTWQRSNIDSNKSKNRYANVVAYDHTSVLLTPVDDVIGSDYINANYIDGYQRQNAYIATQGPLPDTTDDFWRMVWEQRSNCIVMMTRLEERSGIKCHQYWPNRGFICYGQMIVSHIDTFVLAYYTIRLFEIRHSKYSEKREIQHFQFTAWPDHGVPKLSTPLLMFIRRVRSIGKIESCPKIVHCSAGVGRTGAFIVVDAQLERIKQEKNIDVFNYVSKIRCQRNYMVQTQAQYQFILETLLEAVEDGNTEVMACNFHAHVTKLSQIGISGSNQLSGFEMEFSKLNSLASNRGRHGVMLADFVKAAGNQAVNMTKNRVRNIIPYEWNRVVLNAIRGIEGSDYINASYIDGYRDRRAYIAAQSPIPSTVEDFWRMLWDQHCGVVIVLNQPHE---DKSHIYWPINKSIRYQFFVVDPVVEYNMPNYILREFKVTDARDGEFRALRQFQFTQWPNHGCPKESESILDFIRQVHKTKEQFGHMEPMVIHCNTGSGRTGVFIALSIVLDRLQQESVVDMYQTVKLLHKQRIGLVQTEEQYEFCYMAVLDYLSNYE 5814
++P +D +++R + ++ + + P I I L ++ LKAND L E+E+++ +FTW+ SN++ NK KNRYANV+AYDH+ V+L P++ + GSDYINANYIDGY++QNAYIATQGPLP+T DFWRMVWEQR+ +VMMT+LEE+S IKC QYWP+RG YG V+ +DT LA + +R F + + SEKRE++ FQFTAWPDHGVP+ TP L F+RRV++ ++ P I HCSAGVGRTG FIV+DA LERIK EK +D++ +V+ +R QRNYMVQT+ QY FI + LLEAV GNTEV A + ++++ KL+Q + ++G E+EF +L + ++ R F+ A N N KNR+ NI+PYE RV L IRG+EGSDYINAS+IDGYR +RAYI+ Q P+ T EDFWRMLW+ + +V++L + E +K H YWP +S RYQ+FVVDP+ EYNMP YILREFKVTDARDG+ R +RQFQFT WP G PK E +DFI QVHKTKEQFG P+ +HC+ G GRTGVFI LSIVL+R++ E VVD++QTVK+L QR +VQTE++Y+FCY A L+YL +++
Sbjct: 1303 ITPHHPTDPVEVRRINFQTPGMLNHPPIPISELAEHTELLKANDNLKLSQEYESIDPG--QQFTWEHSNLEVNKPKNRYANVIAYDHSRVILAPIEGITGSDYINANYIDGYRKQNAYIATQGPLPETFGDFWRMVWEQRAATVVMMTKLEEKSRIKCDQYWPSRGTETYGMTQVTLLDTIELATFCVRTFSLHKNGSSEKREVRQFQFTAWPDHGVPEYPTPFLAFLRRVKTCNPPDAGPIIAHCSAGVGRTGCFIVIDAMLERIKHEKTVDIYGHVTLMRSQRNYMVQTEDQYSFIHDALLEAVACGNTEVAARSLYSYIQKLAQ--VESGEHVTGMELEFKRLANSKAHTSR-------FISA--NLPCNKFKNRLVNIMPYETTRVCLQPIRGLEGSDYINASFIDGYRQQRAYISTQGPLAETTEDFWRMLWENNSTIVVMLTKLREMGREKCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDARDGQSRTVRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKEQFGQDGPISVHCSAGVGRTGVFITLSIVLERMRYEGVVDIFQTVKMLRTQRPAMVQTEDEYQFCYHAALEYLGSFD 1901 HSP 2 Score: 203.756 bits (517), Expect = 5.374e-52 Identity = 105/262 (40.08%), Postives = 150/262 (57.25%), Query Frame = 1
Query: 5092 NQAVNMTKNRVRNIIPYEWNRVVLNAIRGIEGSDYINASYIDGYRDRRAYIAAQSPIPSTVEDFWRMLWDQHCGVVIVLNQPHEDKSHI----YWPINKSIRYQFFVVDPVVEYNMPNYILREFKVTDARDGEFRALRQFQFTQWPNHGCPKESESILDFIRQVHKTKEQFGHMEPMVIHCNTGSGRTGVFIALSIVLDRLQQESVVDMYQTVKLLHKQRIGLVQTEEQYEFCYMAVLDYLSNYEKILEKSHLY*TYQDLSE 5865
N VN KNR N+I Y+ +RV+L I GI GSDYINA+YIDGYR + AYIA Q P+P T DFWRM+W+Q V+++ + E+KS I YWP + Y V + + + +R F + E R +RQFQFT WP+HG P+ L F+R+V P++ HC+ G GRTG FI + +L+R++ E VD+Y V L+ QR +VQTE+QY F + A+L+ ++ + LY Q L++
Sbjct: 1369 NLEVNKPKNRYANVIAYDHSRVILAPIEGITGSDYINANYIDGYRKQNAYIATQGPLPETFGDFWRMVWEQRAATVVMMTK-LEEKSRIKCDQYWPSRGTETYGMTQVTLLDTIELATFCVRTFSLHKNGSSEKREVRQFQFTAWPDHGVPEYPTPFLAFLRRVKTCNPP--DAGPIIAHCSAGVGRTGCFIVIDAMLERIKHEKTVDIYGHVTLMRSQRNYMVQTEDQYSFIHDALLEAVACGNTEVAARSLYSYIQKLAQ 1627 HSP 3 Score: 137.502 bits (345), Expect = 9.953e-32 Identity = 218/964 (22.61%), Postives = 375/964 (38.90%), Query Frame = 1
Query: 313 PKISLIIQSPNVLLFKSMILACSSTGHPVPSISWKINESPIEELKSPLKKLQNPPRIFSIKNYQNSVLVITQLIESDSNSVLICEAENNAGFD-SRQQQLKV--ISTETDIPSGF--PVFQNNFFPIIKPYNSNVTLVCQAYGNPPPLIQWFKNYELINESFTKIKILNDG-NLLLVQVTREDKGIYHCQAQNTNGLRLSDPSTLDITSYPISPNSLIIERFASDNVEISWRSGLNDVTEQENFILHYREVPENITEKQIMSKFVYLTISEKKSIYKYNLKDLFPFTTYCIWMESENPLGVSPPTIALTVKTLPTSPQLSPRSITATSISNTAILVAWRPPERKFGKFKYYQIIYTNNDGFLPQHWRQFAVKDDNV-MLTHLIASELYHIRVKIVNEIGHGPLSKTISIKTIAGTLSQCPDFKITEIFQSHIKLQWGTPDPVKLFKLIQYNLLCWDVRLKIVNATAKSSTLFPILNHNLSMNEMEYVLYLKNEKEIKCRLSAINSDGKGMPTE--IQASTVNKGVNYQNLIHIDKIGSTYITFQWRPPSKFS----FDYFLWIYQIFDSEKLDRAVKLPKIKINISDSASAE-----NGWFVYNYTNAFSSSRYILGLR-----YLCRDSTDILREYVHRSDLVSTMKSVPSDSPKDLVVKEIDSNSALVSWKPLDQVHSNGIITHYEVRYYAPKKEES-----TERFINVSETSAILSNLKY-FHYVIYVRAFTKVGGGSWSNPKNYYRQNLEEFPIPTTIKGERKSETEINISWELPVLSEKNLAHAAIEGF--------IILYAPVESSPKWIKYTVQSKNLSAVIKGLEPDLRYQFQIAATNYAGFNGNFSEIVQEM--PKNFPN--LNLKTVPDLRCSVQSSNRLKVEWSSPSISTDLLKFEIRYSGNLSYITEIGLKKSEFIDME-SKSVNFETLVNRYDVTLENLQSNALYKIAVRA 3078
P I + Q V ++ + C+++G+P P I+W + PI+ S + IK ++ L I E+D C A N G S L V + +P F P P +V + C A G+P P ++W N +E T + G N+L + RE Y C A ++ G+ + + + + S P P + ++ + +V I+W SG D +I+ Y+ K SK Y T+ + + +Y++ L+P T Y I + + N +G PP+ + +T +P PR++ + ++V W PE G+ K Y++ YT + +W V+D + + L E Y I+V +G GP S I +K + G Q F++ + + I+L W +P + I+ +++R + N + F + V L+ E L+AI+ G G T +Q + K I ST + WRPP S + +YQ+ + P + I + W Y+ T S+ ++GL +CR D VP P+ + V ++S + V W+ L NG I Y+V Y + ES + + ++ LK Y I V A+T G G+ S PK + P P + + S+T + W+ P L+ ++G+ I A +E +P+ +Y+V + + A Y F++AA + GF E V E+ P+N P +K ++ C + + WS P ++ ITE L E E + + ++ Y L +L+ N+ Y++ +RA
Sbjct: 137 PNIDMGPQLKVVERTRTATMLCAASGNPDPEITWYKDFLPIDPSASNGR----------IKQLRSGALQIENSEETDQGKYE-CVASNVEGVRYSSPANLYVRELREVRRVPPRFSIPPTSQEIMP-----GGSVNITCVAVGSPMPYVKWMLN----SEDLTPEDEMPVGRNVLELSSVRESAN-YTCVAMSSLGI-IESVAQITVKSLPKPPGTPVVTETTATSVTITWDSGNPDPVSY--YIIQYKA-------KSPDSK--YETVDDITTT-RYSIGGLYPNTEYEIRVSAINTIGQGPPSEPVETRTGEQAPASPPRNVNGQILPQNTMMVTWEEPEEPNGQIKGYRVYYTMDASQPMSNWHIHNVQDSVITTIRSLTPLETYTIKVLAFTSVGDGPFSPPIKVKVVQGVPGQPSKFQVGAVSDTSIELIW---EPAHDKEAIRR----YELRYRESNHGNQMKKTF-------DPTKSYVVESLRPNTEYYFSLAAISDKGIGAFTNEILQKTLQAKPSAPPQEIECSSTSSTSLLVSWRPPPLKSQNGDLTGYKVLYQVVSPSEGAGGDPQPTEEPMIPPTEEQVLLQRLGKWTQYHIT---VSAATVVGLGPESEPIICRTDED-----------------VPGAPPRRVEVDVLNSTAIKVMWRSLTPGKQNGQIRGYQVHYVRVENGESRGLPLIKDVMLADAQEMVIGGLKPDTTYSITVAAYTTKGDGARSKPKLVVTKGA--VPGPPYLSVAQNSKTSAVVHWDPPDLTNG----MDLQGYRLQFGRKDITPLATLEFAPQERRYSVDNIHRGAT---------YLFKMAAKSRGGFG---EEAVAELSVPENTPGGYPQIKEGSNVTCC-----SVLLSWSPPVLAE-----------RNGVITEYTLVYKEAGTGEIPRELRLHPSLSSY--VLNSLKPNSAYEVKMRA 996 HSP 4 Score: 106.301 bits (264), Expect = 2.930e-22 Identity = 202/907 (22.27%), Postives = 329/907 (36.27%), Query Frame = 1
Query: 370 LACSSTGHPVPSISW-----KINESPIEELKSPLKKLQNPPRIFSIKNYQNSVLVITQLIESDSNSVLICEAENNAGFDSRQQQLKVISTETDIPSGFPVFQNNFFPIIKPYNSNVTLVCQAYGNPPPLIQWFKNYELINESFT--KIKILNDGNLLLVQVTREDKGIYHCQAQNTNGLRLSDPSTLDITS----------YPISPNSLIIERFASDNVE----------ISWRSGLNDVTEQENFILHYREVPENITEKQIMSKFVYLTISEKKSIYKYNLKDLFPFTTYCIWMESENPLGVSPPTIALTVKTLPTSPQLSPRSITATSISNTAILVAWRPPERKFGKFKYYQIIYTNNDGFLPQHWRQFAVKDD----NVMLTHLIASELYHIRVKIVNEIGHGPLSKTISIKTIAGTLSQCPDFKITEIF-QSHIKLQWGTPDPVKLFKLIQYNLLCWDVRLKIVNATAKSSTLFPILNHNLSMNEMEYVLYLKNEKEIKCRLSAINSDGKGMPTEIQASTVNKGVNYQ-NLIHIDKIGSTYITFQWRPPSKFSFDYFLWIYQIFDSEKLDRAVKLPKIKINISDSASAENGWFVYNYTNAF------SSSRYILGLRYLCRDSTDILREYVHRSDLVSTMKSVPSDSPKDLVVKEIDSNSALVSWKPLDQVHSNGIITHYEVRYYAPKKEEST--------ERFINVSETSAILSNL-KYFHYVIYVRAFTKVGGGSWSNPKNYYRQNLEEFP--IPTTIKGERKSETEINISWELPVLSEKNLAHAAIEGFIILYAPVESSPK----WIKYTVQSKNLSAVIKGLEPDLRYQFQIAATNYAGFNGNFSEIVQEMPKNFPNLNLKTVPDLRCSVQSSNRLKVEWSSPSIST--DLLKFEIRYS 2922
C +TG P P +SW K+N IE ++ +VL I L ++ C AEN+ G S +L +I E +P GFP + T++C A GNP P I W+K++ I+ S + +IK L G L + D+G Y C A N G+R S P+ L + + I P S I S N+ + W D+T ++ V N+ L +S + Y C+ M S LG+ +TVK+LP P + T + T++ + W YY I Y P ++ DD + L + Y IRV +N IG GP S+ + +T + P +I Q+ + + W P+ + N R+ ++ + + I HN+ + + + L + ++ A S G G + V +GV Q + + + T I W P D E + R ++ +S ++ T ++ ++ Y L + + + L ++ PS P+++ S S LVSW+P NG +T Y+V Y E E I +E +L L K+ Y I V A T VG G S P + E+ P P ++ + + T I + W ++N I G+ + Y VE+ IK + + VI GL+PD Y +AA G +G S+ + K + P L + S V W P ++ DL + +++
Sbjct: 54 FVCHATGDPKPKVSWSKKGKKVNSQRIETIE--------------FDEGAGAVLRIQPLRAPRDENIYECVAENSEGEISVNARLAIIR-EDLLPPGFPNIDMGPQLKVVERTRTATMLCAASGNPDPEITWYKDFLPIDPSASNGRIKQLRSGALQIENSEETDQGKYECVASNVEGVRYSSPANLYVRELREVRRVPPRFSIPPTSQEIMPGGSVNITCVAVGSPMPYVKWMLNSEDLTPEDEM-----PVGRNV-----------LELSSVRESANYT----------CVAMSS---LGIIESVAQITVKSLPKPPG----TPVVTETTATSVTITWD--SGNPDPVSYYIIQYKAKS---PDS--KYETVDDITTTRYSIGGLYPNTEYEIRVSAINTIGQGPPSEPVETRTGEQAPASPPRNVNGQILPQNTMMVTWEEPE--------EPNGQIKGYRVYYTMDASQPMSNWHI--HNVQDSVITTIRSLTPLETYTIKVLAFTSVGDGPFSPPIKVKVVQGVPGQPSKFQVGAVSDTSIELIWEP--------------AHDKEAIRR------YELRYRESNHGNQMKKTFDPTKSYVVESLRPNTEYYFSLAAISDKGIGAFTNEILQKTL----QAKPSAPPQEIECSSTSSTSLLVSWRPPPLKSQNGDLTGYKVLYQVVSPSEGAGGDPQPTEEPMIPPTEEQVLLQRLGKWTQYHITVSAATVVGLGPESEP--IICRTDEDVPGAPPRRVEVDVLNSTAIKVMWRSLTPGKQN---GQIRGYQVHYVRVENGESRGLPLIKDVMLADAQEMVIGGLKPDTTYSITVAAYTTKG-DGARSKPKLVVTKG----AVPGPPYLSVAQNSKTSAVVHWDPPDLTNGMDLQGYRLQFG 861 HSP 5 Score: 83.1889 bits (204), Expect = 3.322e-15 Identity = 139/618 (22.49%), Postives = 239/618 (38.67%), Query Frame = 1
Query: 913 ITSYPISPNSLIIERFASDNVEISWRSGLNDVTEQENFILHYREVPENITEKQIMSKFVYLTISEKKSIYKYNLKDLFPFTTYCIWMESENPLGVSPPTIALTVKTLPTSPQLSPRSITATSISNTAILVAWRPPERKF--GKFKYYQIIY-----TNNDGFLPQHWRQFAVK--DDNVMLTHLIASELYHIRVKIVNEIGHGPLSKTISIKTIAGTLSQCPDFKITEIFQS-HIKLQWGTPDPVKLFKLIQYNLLCWDVRLKIVNATAKSSTLFPILNHNLSMNEMEYVLY-LKNEKEIKCRLSAINSDGKGMPTEIQASTVNKGVNYQNLIHIDKIGSTYITFQWRPPSKFSFDYFLWIYQIFDSEKLDRAVKLPKIKINISDSASAENGWFVYNYTNAFSSSRYILGLRYLCRDSTDILREYVHRSDLVSTMKSVPSDSPKDLVVKEIDSNSALVSWKPLDQVHSNGIITHYEVRYY-APKKEESTERFINVSETSAILSNLK-YFHYVIYVRAFTKVGGGSWSNPKNYYRQNLEEFPIPTTIKGERKSETEINISWELPVLSEKNLAHAAIEGFIILYAPVESSPKWIKYTVQSKNLSAVIKGLEPDLRYQFQI 2727
+ P P+ + + ++E+ W +D + L YRE K+ T KS Y ++ L P T Y + + + G+ T + KTL P P+ I +S S+T++LV+WRPP K G Y+++Y + G PQ + + ++ V+L L YHI V +G GP S+ I +T P ++ S IK+ W + P K I+ ++ V S P++ + + E V+ LK + ++A + G G ++ + V + + + T W PP + L Y++ + R P + + Y+ N + Y+ + R E V +S ++ P P+ + S L+SW P NG+IT Y + Y A E E ++ S +S +L++LK Y + +RA T VG G +S P Y + +P + ++T + + W+ SE++ IE YA K V ++ L A IKGL + Y+F++
Sbjct: 514 VQGVPGQPSKFQVGAVSDTSIELIWEPA-HDKEAIRRYELRYRESNHGNQMKK--------TFDPTKS---YVVESLRPNTEYYFSLAAISDKGIGAFTNEILQKTLQAKPSAPPQEIECSSTSSTSLLVSWRPPPLKSQNGDLTGYKVLYQVVSPSEGAGGDPQPTEEPMIPPTEEQVLLQRLGKWTQYHITVSAATVVGLGPESEPIICRTDEDVPGAPPRRVEVDVLNSTAIKVMWRSLTPGKQNGQIR------GYQVHYVRVENGESRGLPLIKDVMLADAQEMVIGGLKPDTTYSITVAAYTTKGDGARSKPKLVVTKGAVPGPPYLSVAQNSKTSAVVHWDPPD-LTNGMDLQGYRL----QFGRKDITPLATLEFAPQERR------YSVDNIHRGATYLFKMAAKSRGG--FGEEAVAE---LSVPENTPGGYPQIKEGSNVTCCSVLLSWSPPVLAERNGVITEYTLVYKEAGTGEIPRELRLHPSLSSYVLNSLKPNSAYEVKMRAHTSVGPGPYSPPIQYRTVAIHPADVPKNFTVKWATKTTVVLGWK---FSERSPYKCVIE-----YA-------HQKKDVDARELKAFIKGLRHNTTYEFKV 1082
BLAST of Protein tyrosine phosphatase receptor type D vs. Ensembl Medaka
Match: ptprsa (receptor-type tyrosine-protein phosphatase S [Source:NCBI gene;Acc:101174175]) HSP 1 Score: 712.22 bits (1837), Expect = 0.000e+0 Identity = 330/612 (53.92%), Postives = 440/612 (71.90%), Query Frame = 1
Query: 3988 LSPVLVSDSIKLRIGSQKSENISDRPSISICNLYQYVTDLKANDCTLLQAEFETLNTNLDDRFTWQRSNIDSNKSKNRYANVVAYDHTSVLLTPVDDVIGSDYINANYIDGYQRQNAYIATQGPLPDTTDDFWRMVWEQRSNCIVMMTRLEERSGIKCHQYWPNRGFICYGQMIVSHIDTFVLAYYTIRLFEIRHSKYSEKREIQHFQFTAWPDHGVPKLSTPLLMFIRRVRSIGKIESCPKIVHCSAGVGRTGAFIVVDAQLERIKQEKNIDVFNYVSKIRCQRNYMVQTQAQYQFILETLLEAVEDGNTEVMACNFHAHVTKLSQIGISGSNQLSGFEMEFSKLNSLASNRGRHGVMLADFVKAAGNQAVNMTKNRVRNIIPYEWNRVVLNAIRGIEGSDYINASYIDGYRDRRAYIAAQSPIPSTVEDFWRMLWDQHCGVVIVLNQPHE---DKSHIYWPINKSIRYQFFVVDPVVEYNMPNYILREFKVTDARDGEFRALRQFQFTQWPNHGCPKESESILDFIRQVHKTKEQFGHMEPMVIHCNTGSGRTGVFIALSIVLDRLQQESVVDMYQTVKLLHKQRIGLVQTEEQYEFCYMAVLDYLSNYE 5814
++P +D +++R + ++ + + P I I L ++ LKAND L E+E+++ +FTW+ SN++ NK KNRYANV+AYDH+ V+L P++ + GSDYINANYIDGY++QNAYIATQGPLP+T DFWRMVWEQR+ +VMMT+LEE+S IKC QYWP+RG YG V+ +DT LA + +R F + + SEKRE++ FQFTAWPDHGVP+ TP L F+RRV++ ++ P I HCSAGVGRTG FIV+DA LERIK EK +D++ +V+ +R QRNYMVQT+ QY FI + LLEAV GNTEV A + ++++ KL+Q + ++G E+EF +L + ++ R F+ A N N KNR+ NI+PYE RV L IRG+EGSDYINAS+IDGYR +RAYI+ Q P+ T EDFWRMLW+ + +V++L + E +K H YWP +S RYQ+FVVDP+ EYNMP YILREFKVTDARDG+ R +RQFQFT WP G PK E +DFI QVHKTKEQFG P+ +HC+ G GRTGVFI LSIVL+R++ E VVD++QTVK+L QR +VQTE++Y+FCY A L+YL +++
Sbjct: 1308 ITPHHPTDPVEVRRINFQTPGMLNHPPIPISELAEHTELLKANDNLKLSQEYESIDPG--QQFTWEHSNLEVNKPKNRYANVIAYDHSRVILAPIEGITGSDYINANYIDGYRKQNAYIATQGPLPETFGDFWRMVWEQRAATVVMMTKLEEKSRIKCDQYWPSRGTETYGMTQVTLLDTIELATFCVRTFSLHKNGSSEKREVRQFQFTAWPDHGVPEYPTPFLAFLRRVKTCNPPDAGPIIAHCSAGVGRTGCFIVIDAMLERIKHEKTVDIYGHVTLMRSQRNYMVQTEDQYSFIHDALLEAVACGNTEVAARSLYSYIQKLAQ--VESGEHVTGMELEFKRLANSKAHTSR-------FISA--NLPCNKFKNRLVNIMPYETTRVCLQPIRGLEGSDYINASFIDGYRQQRAYISTQGPLAETTEDFWRMLWENNSTIVVMLTKLREMGREKCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDARDGQSRTVRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKEQFGQDGPISVHCSAGVGRTGVFITLSIVLERMRYEGVVDIFQTVKMLRTQRPAMVQTEDEYQFCYHAALEYLGSFD 1906 HSP 2 Score: 203.756 bits (517), Expect = 5.717e-52 Identity = 105/262 (40.08%), Postives = 150/262 (57.25%), Query Frame = 1
Query: 5092 NQAVNMTKNRVRNIIPYEWNRVVLNAIRGIEGSDYINASYIDGYRDRRAYIAAQSPIPSTVEDFWRMLWDQHCGVVIVLNQPHEDKSHI----YWPINKSIRYQFFVVDPVVEYNMPNYILREFKVTDARDGEFRALRQFQFTQWPNHGCPKESESILDFIRQVHKTKEQFGHMEPMVIHCNTGSGRTGVFIALSIVLDRLQQESVVDMYQTVKLLHKQRIGLVQTEEQYEFCYMAVLDYLSNYEKILEKSHLY*TYQDLSE 5865
N VN KNR N+I Y+ +RV+L I GI GSDYINA+YIDGYR + AYIA Q P+P T DFWRM+W+Q V+++ + E+KS I YWP + Y V + + + +R F + E R +RQFQFT WP+HG P+ L F+R+V P++ HC+ G GRTG FI + +L+R++ E VD+Y V L+ QR +VQTE+QY F + A+L+ ++ + LY Q L++
Sbjct: 1374 NLEVNKPKNRYANVIAYDHSRVILAPIEGITGSDYINANYIDGYRKQNAYIATQGPLPETFGDFWRMVWEQRAATVVMMTK-LEEKSRIKCDQYWPSRGTETYGMTQVTLLDTIELATFCVRTFSLHKNGSSEKREVRQFQFTAWPDHGVPEYPTPFLAFLRRVKTCNPP--DAGPIIAHCSAGVGRTGCFIVIDAMLERIKHEKTVDIYGHVTLMRSQRNYMVQTEDQYSFIHDALLEAVACGNTEVAARSLYSYIQKLAQ 1632 HSP 3 Score: 136.346 bits (342), Expect = 2.041e-31 Identity = 217/969 (22.39%), Postives = 373/969 (38.49%), Query Frame = 1
Query: 313 PKISLIIQSPNVLLFKSMILACSSTGHPVPSISWKINESPIEELKSPLKKLQNPPRIFSIKNYQNSVLVITQLIESDSNSVLICEAENNAGFD-SRQQQLKVISTETDIPSGFPVFQNNFFPIIKPYNSNVTLVCQAYGNPPPLIQWFKNYELINESFTKIKILNDG-NLLLVQVTREDKGIYHCQAQNTNGLRLSDPSTLDITSYPISPNSLIIERFASDNVEISWRSGLNDVTEQENFILHYREVPENITEKQIMSKFVYLTISEKKSIYKYNLKDLFPFTTYCIWMESENPLGVSPPTIALTVKTLPTSPQLSPRSITATSISNTAILVAWRPPERKFGKFKYYQIIYTNNDGFLPQHWRQFAVKDDNV-MLTHLIASELYHIRVKIVNEIGHGPLSKTISIKTIAGTLSQCPDFKITEIFQSHIKLQWGTPDPVKLFKLIQYNLLCWDVRLKIVNATAKSSTLFPILNHNLSMNEMEYVLYLKNEKEIKCRLSAINSDGKGMPTE--IQASTVNKGVNYQNLIHIDKIGSTYITFQWRPPSKFS----FDYFLWIYQIFDSEKLDRAVKLPKIKINISDSASAE-----NGWFVYNYTNAFSSSRYILGLR-----YLCRDSTDILREYVHRSDLVSTMKSVPSDSPKDLVVKEIDSNSALVSWKPLDQVHSNGIITHYEVRYYAPKKEESTERFI--------------NVSETSAILSNLKY-FHYVIYVRAFTKVGGGSWSNPKNYYRQNLEEFPIPTTIKGERKSETEINISWELPVLSEKNLAHAAIEGF--------IILYAPVESSPKWIKYTVQSKNLSAVIKGLEPDLRYQFQIAATNYAGFNGNFSEIVQEM--PKNFPN--LNLKTVPDLRCSVQSSNRLKVEWSSPSISTDLLKFEIRYSGNLSYITEIGLKKSEFIDME-SKSVNFETLVNRYDVTLENLQSNALYKIAVRA 3078
P I + Q V ++ + C+++G+P P I+W + PI+ S + IK ++ L I E+D C A N G S L V P P +V + C A G+P P ++W N +E T + G N+L + RE Y C A ++ G+ + + + + S P P + ++ + +V I+W SG D +I+ Y+ K SK Y T+ + + +Y++ L+P T Y I + + N +G PP+ + +T +P PR++ + ++V W PE G+ K Y++ YT + +W V+D + + L E Y I+V +G GP S I +K + G Q F++ + + I+L W +P + I+ +++R + N + F + V L+ E L+AI+ G G T +Q + K I ST + WRPP S + +YQ+ + P + I + W Y+ T S+ ++GL +CR D VP P+ + V ++S + V W+ L NG I Y+V Y + ES + + +E ++ LK Y I V A+T G G+ S PK + P P + + S+T + W+ P L+ ++G+ I A +E +P+ +Y+V + + A Y F++AA + GF E V E+ P+N P +K ++ C + + WS P ++ ITE L E E + + ++ Y L +L+ N+ Y++ +RA
Sbjct: 137 PNIDMGPQLKVVERTRTATMLCAASGNPDPEITWYKDFLPIDPSASNGR----------IKQLRSGALQIENSEETDQGKYE-CVASNVEGVRYSSPANLYVRVRRVPPRFSIPPTSQEIMP-----GGSVNITCVAVGSPMPYVKWMLN----SEDLTPEDEMPVGRNVLELSSVRESAN-YTCVAMSSLGI-IESVAQITVKSLPKPPGTPVVTETTATSVTITWDSGNPDPVSY--YIIQYKA-------KSPDSK--YETVDDITTT-RYSIGGLYPNTEYEIRVSAINTIGQGPPSEPVETRTGEQAPASPPRNVNGQILPQNTMMVTWEEPEEPNGQIKGYRVYYTMDASQPMSNWHIHNVQDSVITTIRSLTPLETYTIKVLAFTSVGDGPFSPPIKVKVVQGVPGQPSKFQVGAVSDTSIELIW---EPAHDKEAIRR----YELRYRESNHGNQMKKTF-------DPTKSYVVESLRPNTEYYFSLAAISDKGIGAFTNEILQKTLQAKPSAPPQEIECSSTSSTSLLVSWRPPPLKSQNGDLTGYKVLYQVVSPSEGAGGDPQPTEEPMIPPTEEQVLLQRLGKWTQYHIT---VSAATVVGLGPESEPIICRTDED-----------------VPGAPPRRVEVDVLNSTAIKVMWRSLTPGKQNGQIRGYQVHYVRVENGESRGLPLIKDVMLADAQWETDDTAEYEMVIGGLKPDTTYSITVAAYTTKGDGARSKPKLVVTKGA--VPGPPYLSVAQNSKTSAVVHWDPPDLTNG----MDLQGYRLQFGRKDITPLATLEFAPQERRYSVDNIHRGAT---------YLFKMAAKSRGGFG---EEAVAELSVPENTPGGYPQIKEGSNVTCC-----SVLLSWSPPVLAE-----------RNGVITEYTLVYKEAGTGEIPRELRLHPSLSSY--VLNSLKPNSAYEVKMRA 1001 HSP 4 Score: 103.219 bits (256), Expect = 2.827e-21 Identity = 202/914 (22.10%), Postives = 329/914 (36.00%), Query Frame = 1
Query: 370 LACSSTGHPVPSISW-----KINESPIEELKSPLKKLQNPPRIFSIKNYQNSVLVITQLIESDSNSVLICEAENNAGFDSRQQQLKVISTETDIPSGFPVFQNNFFPIIKPYNSNVTLVCQAYGNPPPLIQWFKNYELINESFT--KIKILNDGNLLLVQVTREDKGIYHCQAQNTNGLRLSDPSTLDI------TSYPISPNSLIIERFASDNVE----------ISWRSGLNDVTEQENFILHYREVPENITEKQIMSKFVYLTISEKKSIYKYNLKDLFPFTTYCIWMESENPLGVSPPTIALTVKTLPTSPQLSPRSITATSISNTAILVAWRPPERKFGKFKYYQIIYTNNDGFLPQHWRQFAVKDD----NVMLTHLIASELYHIRVKIVNEIGHGPLSKTISIKTIAGTLSQCPDFKITEIF-QSHIKLQWGTPDPVKLFKLIQYNLLCWDVRLKIVNATAKSSTLFPILNHNLSMNEMEYVLYLKNEKEIKCRLSAINSDGKGMPTEIQASTVNKGVNYQ-NLIHIDKIGSTYITFQWRPPSKFSFDYFLWIYQIFDSEKLDRAVKLPKIKINISDSASAENGWFVYNYTNAF------SSSRYILGLRYLCRDSTDILREYVHRSDLVSTMKSVPSDSPKDLVVKEIDSNSALVSWKPLDQVHSNGIITHYEVRYYAPKKEEST--------ERFINVSETSAILSNL-KYFHYVIYVRAFTKVGGGSWSNPKNYYRQNLEEFP--IPTTIKGERKSETEINISWELPVLSEKNLAHAAIEGFIILYAPVE---------------SSPKWIKYTVQSKNLSAVIKGLEPDLRYQFQIAATNYAGFNGNFSEIVQEMPKNFPNLNLKTVPDLRCSVQSSNRLKVEWSSPSIST--DLLKFEIRYS 2922
C +TG P P +SW K+N IE ++ +VL I L ++ C AEN+ G S +L +I E +P GFP + T++C A GNP P I W+K++ I+ S + +IK L G L + D+G Y C A N G+R S P+ L + + I P S I S N+ + W D+T ++ V N+ L +S + Y C+ M S LG+ +TVK+LP P + T + T++ + W YY I Y P ++ DD + L + Y IRV +N IG GP S+ + +T + P +I Q+ + + W P+ + N R+ ++ + + I HN+ + + + L + ++ A S G G + V +GV Q + + + T I W P D E + R ++ +S ++ T ++ ++ Y L + + + L ++ PS P+++ S S LVSW+P NG +T Y+V Y E E I +E +L L K+ Y I V A T VG G S P + E+ P P ++ + + T I + W ++N I G+ + Y VE + +W T + VI GL+PD Y +AA G +G S+ + K + P L + S V W P ++ DL + +++
Sbjct: 54 FVCHATGDPKPKVSWSKKGKKVNSQRIETIE--------------FDEGAGAVLRIQPLRAPRDENIYECVAENSEGEISVNARLAIIR-EDLLPPGFPNIDMGPQLKVVERTRTATMLCAASGNPDPEITWYKDFLPIDPSASNGRIKQLRSGALQIENSEETDQGKYECVASNVEGVRYSSPANLYVRVRRVPPRFSIPPTSQEIMPGGSVNITCVAVGSPMPYVKWMLNSEDLTPEDEM-----PVGRNV-----------LELSSVRESANYT----------CVAMSS---LGIIESVAQITVKSLPKPPG----TPVVTETTATSVTITWD--SGNPDPVSYYIIQYKAKS---PDS--KYETVDDITTTRYSIGGLYPNTEYEIRVSAINTIGQGPPSEPVETRTGEQAPASPPRNVNGQILPQNTMMVTWEEPE--------EPNGQIKGYRVYYTMDASQPMSNWHI--HNVQDSVITTIRSLTPLETYTIKVLAFTSVGDGPFSPPIKVKVVQGVPGQPSKFQVGAVSDTSIELIWEP--------------AHDKEAIRR------YELRYRESNHGNQMKKTFDPTKSYVVESLRPNTEYYFSLAAISDKGIGAFTNEILQKTL----QAKPSAPPQEIECSSTSSTSLLVSWRPPPLKSQNGDLTGYKVLYQVVSPSEGAGGDPQPTEEPMIPPTEEQVLLQRLGKWTQYHITVSAATVVGLGPESEP--IICRTDEDVPGAPPRRVEVDVLNSTAIKVMWRSLTPGKQN---GQIRGYQVHYVRVENGESRGLPLIKDVMLADAQW--ETDDTAEYEMVIGGLKPDTTYSITVAAYTTKG-DGARSKPKLVVTKG----AVPGPPYLSVAQNSKTSAVVHWDPPDLTNGMDLQGYRLQFG 866 HSP 5 Score: 77.0258 bits (188), Expect = 1.970e-13 Identity = 140/627 (22.33%), Postives = 240/627 (38.28%), Query Frame = 1
Query: 913 ITSYPISPNSLIIERFASDNVEISWRSGLNDVTEQENFILHYREVPENITEKQIMSKFVYLTISEKKSIYKYNLKDLFPFTTYCIWMESENPLGVSPPTIALTVKTLPTSPQLSPRSITATSISNTAILVAWRPPERKF--GKFKYYQIIY-----TNNDGFLPQHWRQFAVK--DDNVMLTHLIASELYHIRVKIVNEIGHGPLSKTISIKTIAGTLSQCPDFKITEIFQS-HIKLQWGTPDPVKLFKLIQYNLLCWDVRLKIVNATAKSSTLFPILNHNLSMN---------EMEYVLY-LKNEKEIKCRLSAINSDGKGMPTEIQASTVNKGVNYQNLIHIDKIGSTYITFQWRPPSKFSFDYFLWIYQIFDSEKLDRAVKLPKIKINISDSASAENGWFVYNYTNAFSSSRYILGLRYLCRDSTDILREYVHRSDLVSTMKSVPSDSPKDLVVKEIDSNSALVSWKPLDQVHSNGIITHYEVRYY-APKKEESTERFINVSETSAILSNLK-YFHYVIYVRAFTKVGGGSWSNPKNYYRQNLEEFPIPTTIKGERKSETEINISWELPVLSEKNLAHAAIEGFIILYAPVESSPKWIKYTVQSKNLSAVIKGLEPDLRYQFQI 2727
+ P P+ + + ++E+ W +D + L YRE K+ T KS Y ++ L P T Y + + + G+ T + KTL P P+ I +S S+T++LV+WRPP K G Y+++Y + G PQ + + ++ V+L L YHI V +G GP S+ I +T P ++ S IK+ W + P K I+ ++ V S P++ + + E E V+ LK + ++A + G G ++ + V + + + T W PP + L Y++ + R P + + Y+ N + Y+ + R E V +S ++ P P+ + S L+SW P NG+IT Y + Y A E E ++ S +S +L++LK Y + +RA T VG G +S P Y + +P + ++T + + W+ SE++ IE YA K V ++ L A IKGL + Y+F++
Sbjct: 510 VQGVPGQPSKFQVGAVSDTSIELIWEPA-HDKEAIRRYELRYRESNHGNQMKK--------TFDPTKS---YVVESLRPNTEYYFSLAAISDKGIGAFTNEILQKTLQAKPSAPPQEIECSSTSSTSLLVSWRPPPLKSQNGDLTGYKVLYQVVSPSEGAGGDPQPTEEPMIPPTEEQVLLQRLGKWTQYHITVSAATVVGLGPESEPIICRTDEDVPGAPPRRVEVDVLNSTAIKVMWRSLTPGKQNGQIR------GYQVHYVRVENGESRGLPLIKDVMLADAQWETDDTAEYEMVIGGLKPDTTYSITVAAYTTKGDGARSKPKLVVTKGAVPGPPYLSVAQNSKTSAVVHWDPPD-LTNGMDLQGYRL----QFGRKDITPLATLEFAPQERR------YSVDNIHRGATYLFKMAAKSRGG--FGEEAVAE---LSVPENTPGGYPQIKEGSNVTCCSVLLSWSPPVLAERNGVITEYTLVYKEAGTGEIPRELRLHPSLSSYVLNSLKPNSAYEVKMRAHTSVGPGPYSPPIQYRTVAIHPADVPKNFTVKWATKTTVVLGWK---FSERSPYKCVIE-----YA-------HQKKDVDARELKAFIKGLRHNTTYEFKV 1087
BLAST of Protein tyrosine phosphatase receptor type D vs. Ensembl Medaka
Match: ptprsa (receptor-type tyrosine-protein phosphatase S [Source:NCBI gene;Acc:101174175]) HSP 1 Score: 712.22 bits (1837), Expect = 0.000e+0 Identity = 330/612 (53.92%), Postives = 440/612 (71.90%), Query Frame = 1
Query: 3988 LSPVLVSDSIKLRIGSQKSENISDRPSISICNLYQYVTDLKANDCTLLQAEFETLNTNLDDRFTWQRSNIDSNKSKNRYANVVAYDHTSVLLTPVDDVIGSDYINANYIDGYQRQNAYIATQGPLPDTTDDFWRMVWEQRSNCIVMMTRLEERSGIKCHQYWPNRGFICYGQMIVSHIDTFVLAYYTIRLFEIRHSKYSEKREIQHFQFTAWPDHGVPKLSTPLLMFIRRVRSIGKIESCPKIVHCSAGVGRTGAFIVVDAQLERIKQEKNIDVFNYVSKIRCQRNYMVQTQAQYQFILETLLEAVEDGNTEVMACNFHAHVTKLSQIGISGSNQLSGFEMEFSKLNSLASNRGRHGVMLADFVKAAGNQAVNMTKNRVRNIIPYEWNRVVLNAIRGIEGSDYINASYIDGYRDRRAYIAAQSPIPSTVEDFWRMLWDQHCGVVIVLNQPHE---DKSHIYWPINKSIRYQFFVVDPVVEYNMPNYILREFKVTDARDGEFRALRQFQFTQWPNHGCPKESESILDFIRQVHKTKEQFGHMEPMVIHCNTGSGRTGVFIALSIVLDRLQQESVVDMYQTVKLLHKQRIGLVQTEEQYEFCYMAVLDYLSNYE 5814
++P +D +++R + ++ + + P I I L ++ LKAND L E+E+++ +FTW+ SN++ NK KNRYANV+AYDH+ V+L P++ + GSDYINANYIDGY++QNAYIATQGPLP+T DFWRMVWEQR+ +VMMT+LEE+S IKC QYWP+RG YG V+ +DT LA + +R F + + SEKRE++ FQFTAWPDHGVP+ TP L F+RRV++ ++ P I HCSAGVGRTG FIV+DA LERIK EK +D++ +V+ +R QRNYMVQT+ QY FI + LLEAV GNTEV A + ++++ KL+Q + ++G E+EF +L + ++ R F+ A N N KNR+ NI+PYE RV L IRG+EGSDYINAS+IDGYR +RAYI+ Q P+ T EDFWRMLW+ + +V++L + E +K H YWP +S RYQ+FVVDP+ EYNMP YILREFKVTDARDG+ R +RQFQFT WP G PK E +DFI QVHKTKEQFG P+ +HC+ G GRTGVFI LSIVL+R++ E VVD++QTVK+L QR +VQTE++Y+FCY A L+YL +++
Sbjct: 1312 ITPHHPTDPVEVRRINFQTPGMLNHPPIPISELAEHTELLKANDNLKLSQEYESIDPG--QQFTWEHSNLEVNKPKNRYANVIAYDHSRVILAPIEGITGSDYINANYIDGYRKQNAYIATQGPLPETFGDFWRMVWEQRAATVVMMTKLEEKSRIKCDQYWPSRGTETYGMTQVTLLDTIELATFCVRTFSLHKNGSSEKREVRQFQFTAWPDHGVPEYPTPFLAFLRRVKTCNPPDAGPIIAHCSAGVGRTGCFIVIDAMLERIKHEKTVDIYGHVTLMRSQRNYMVQTEDQYSFIHDALLEAVACGNTEVAARSLYSYIQKLAQ--VESGEHVTGMELEFKRLANSKAHTSR-------FISA--NLPCNKFKNRLVNIMPYETTRVCLQPIRGLEGSDYINASFIDGYRQQRAYISTQGPLAETTEDFWRMLWENNSTIVVMLTKLREMGREKCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDARDGQSRTVRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKEQFGQDGPISVHCSAGVGRTGVFITLSIVLERMRYEGVVDIFQTVKMLRTQRPAMVQTEDEYQFCYHAALEYLGSFD 1910 HSP 2 Score: 203.756 bits (517), Expect = 6.026e-52 Identity = 105/262 (40.08%), Postives = 150/262 (57.25%), Query Frame = 1
Query: 5092 NQAVNMTKNRVRNIIPYEWNRVVLNAIRGIEGSDYINASYIDGYRDRRAYIAAQSPIPSTVEDFWRMLWDQHCGVVIVLNQPHEDKSHI----YWPINKSIRYQFFVVDPVVEYNMPNYILREFKVTDARDGEFRALRQFQFTQWPNHGCPKESESILDFIRQVHKTKEQFGHMEPMVIHCNTGSGRTGVFIALSIVLDRLQQESVVDMYQTVKLLHKQRIGLVQTEEQYEFCYMAVLDYLSNYEKILEKSHLY*TYQDLSE 5865
N VN KNR N+I Y+ +RV+L I GI GSDYINA+YIDGYR + AYIA Q P+P T DFWRM+W+Q V+++ + E+KS I YWP + Y V + + + +R F + E R +RQFQFT WP+HG P+ L F+R+V P++ HC+ G GRTG FI + +L+R++ E VD+Y V L+ QR +VQTE+QY F + A+L+ ++ + LY Q L++
Sbjct: 1378 NLEVNKPKNRYANVIAYDHSRVILAPIEGITGSDYINANYIDGYRKQNAYIATQGPLPETFGDFWRMVWEQRAATVVMMTK-LEEKSRIKCDQYWPSRGTETYGMTQVTLLDTIELATFCVRTFSLHKNGSSEKREVRQFQFTAWPDHGVPEYPTPFLAFLRRVKTCNPP--DAGPIIAHCSAGVGRTGCFIVIDAMLERIKHEKTVDIYGHVTLMRSQRNYMVQTEDQYSFIHDALLEAVACGNTEVAARSLYSYIQKLAQ 1636 HSP 3 Score: 135.961 bits (341), Expect = 3.140e-31 Identity = 219/973 (22.51%), Postives = 377/973 (38.75%), Query Frame = 1
Query: 313 PKISLIIQSPNVLLFKSMILACSSTGHPVPSISWKINESPIEELKSPLKKLQNPPRIFSIKNYQNSVLVITQLIESDSNSVLICEAENNAGFD-SRQQQLKV--ISTETDIPSGF--PVFQNNFFPIIKPYNSNVTLVCQAYGNPPPLIQWFKNYELINESFTKIKILNDG-NLLLVQVTREDKGIYHCQAQNTNGLRLSDPSTLDITSYPISPNSLIIERFASDNVEISWRSGLNDVTEQENFILHYREVPENITEKQIMSKFVYLTISEKKSIYKYNLKDLFPFTTYCIWMESENPLGVSPPTIALTVKTLPTSPQLSPRSITATSISNTAILVAWRPPERKFGKFKYYQIIYTNNDGFLPQHWRQFAVKDDNV-MLTHLIASELYHIRVKIVNEIGHGPLSKTISIKTIAGTLSQCPDFKITEIFQSHIKLQWGTPDPVKLFKLIQYNLLCWDVRLKIVNATAKSSTLFPILNHNLSMNEMEYVLYLKNEKEIKCRLSAINSDGKGMPTE--IQASTVNKGVNYQNLIHIDKIGSTYITFQWRPPSKFS----FDYFLWIYQIFDSEKLDRAVKLPKIKINISDSASAE-----NGWFVYNYTNAFSSSRYILGLR-----YLCRDSTDILREYVHRSDLVSTMKSVPSDSPKDLVVKEIDSNSALVSWKPLDQVHSNGIITHYEVRYYAPKKEESTERFI--------------NVSETSAILSNLKY-FHYVIYVRAFTKVGGGSWSNPKNYYRQNLEEFPIPTTIKGERKSETEINISWELPVLSEKNLAHAAIEGF--------IILYAPVESSPKWIKYTVQSKNLSAVIKGLEPDLRYQFQIAATNYAGFNGNFSEIVQEM--PKNFPN--LNLKTVPDLRCSVQSSNRLKVEWSSPSISTDLLKFEIRYSGNLSYITEIGLKKSEFIDME-SKSVNFETLVNRYDVTLENLQSNALYKIAVRA 3078
P I + Q V ++ + C+++G+P P I+W + PI+ S + IK ++ L I E+D C A N G S L V + +P F P P +V + C A G+P P ++W N +E T + G N+L + RE Y C A ++ G+ + + + + S P P + ++ + +V I+W SG D +I+ Y+ K SK Y T+ + + +Y++ L+P T Y I + + N +G PP+ + +T +P PR++ + ++V W PE G+ K Y++ YT + +W V+D + + L E Y I+V +G GP S I +K + G Q F++ + + I+L W +P + I+ +++R + N + F + V L+ E L+AI+ G G T +Q + K I ST + WRPP S + +YQ+ + P + I + W Y+ T S+ ++GL +CR D VP P+ + V ++S + V W+ L NG I Y+V Y + ES + + +E ++ LK Y I V A+T G G+ S PK + P P + + S+T + W+ P L+ ++G+ I A +E +P+ +Y+V + + A Y F++AA + GF E V E+ P+N P +K ++ C + + WS P ++ ITE L E E + + ++ Y L +L+ N+ Y++ +RA
Sbjct: 137 PNIDMGPQLKVVERTRTATMLCAASGNPDPEITWYKDFLPIDPSASNGR----------IKQLRSGALQIENSEETDQGKYE-CVASNVEGVRYSSPANLYVRELREVRRVPPRFSIPPTSQEIMP-----GGSVNITCVAVGSPMPYVKWMLN----SEDLTPEDEMPVGRNVLELSSVRESAN-YTCVAMSSLGI-IESVAQITVKSLPKPPGTPVVTETTATSVTITWDSGNPDPVSY--YIIQYKA-------KSPDSK--YETVDDITTT-RYSIGGLYPNTEYEIRVSAINTIGQGPPSEPVETRTGEQAPASPPRNVNGQILPQNTMMVTWEEPEEPNGQIKGYRVYYTMDASQPMSNWHIHNVQDSVITTIRSLTPLETYTIKVLAFTSVGDGPFSPPIKVKVVQGVPGQPSKFQVGAVSDTSIELIW---EPAHDKEAIRR----YELRYRESNHGNQMKKTF-------DPTKSYVVESLRPNTEYYFSLAAISDKGIGAFTNEILQKTLQAKPSAPPQEIECSSTSSTSLLVSWRPPPLKSQNGDLTGYKVLYQVVSPSEGAGGDPQPTEEPMIPPTEEQVLLQRLGKWTQYHIT---VSAATVVGLGPESEPIICRTDED-----------------VPGAPPRRVEVDVLNSTAIKVMWRSLTPGKQNGQIRGYQVHYVRVENGESRGLPLIKDVMLADAQWETDDTAEYEMVIGGLKPDTTYSITVAAYTTKGDGARSKPKLVVTKGA--VPGPPYLSVAQNSKTSAVVHWDPPDLTNG----MDLQGYRLQFGRKDITPLATLEFAPQERRYSVDNIHRGAT---------YLFKMAAKSRGGFG---EEAVAELSVPENTPGGYPQIKEGSNVTCC-----SVLLSWSPPVLAE-----------RNGVITEYTLVYKEAGTGEIPRELRLHPSLSSY--VLNSLKPNSAYEVKMRA 1005 HSP 4 Score: 101.679 bits (252), Expect = 7.837e-21 Identity = 202/918 (22.00%), Postives = 329/918 (35.84%), Query Frame = 1
Query: 370 LACSSTGHPVPSISW-----KINESPIEELKSPLKKLQNPPRIFSIKNYQNSVLVITQLIESDSNSVLICEAENNAGFDSRQQQLKVISTETDIPSGFPVFQNNFFPIIKPYNSNVTLVCQAYGNPPPLIQWFKNYELINESFT--KIKILNDGNLLLVQVTREDKGIYHCQAQNTNGLRLSDPSTLDITS----------YPISPNSLIIERFASDNVE----------ISWRSGLNDVTEQENFILHYREVPENITEKQIMSKFVYLTISEKKSIYKYNLKDLFPFTTYCIWMESENPLGVSPPTIALTVKTLPTSPQLSPRSITATSISNTAILVAWRPPERKFGKFKYYQIIYTNNDGFLPQHWRQFAVKDD----NVMLTHLIASELYHIRVKIVNEIGHGPLSKTISIKTIAGTLSQCPDFKITEIF-QSHIKLQWGTPDPVKLFKLIQYNLLCWDVRLKIVNATAKSSTLFPILNHNLSMNEMEYVLYLKNEKEIKCRLSAINSDGKGMPTEIQASTVNKGVNYQ-NLIHIDKIGSTYITFQWRPPSKFSFDYFLWIYQIFDSEKLDRAVKLPKIKINISDSASAENGWFVYNYTNAF------SSSRYILGLRYLCRDSTDILREYVHRSDLVSTMKSVPSDSPKDLVVKEIDSNSALVSWKPLDQVHSNGIITHYEVRYYAPKKEEST--------ERFINVSETSAILSNL-KYFHYVIYVRAFTKVGGGSWSNPKNYYRQNLEEFP--IPTTIKGERKSETEINISWELPVLSEKNLAHAAIEGFIILYAPVE---------------SSPKWIKYTVQSKNLSAVIKGLEPDLRYQFQIAATNYAGFNGNFSEIVQEMPKNFPNLNLKTVPDLRCSVQSSNRLKVEWSSPSIST--DLLKFEIRYS 2922
C +TG P P +SW K+N IE ++ +VL I L ++ C AEN+ G S +L +I E +P GFP + T++C A GNP P I W+K++ I+ S + +IK L G L + D+G Y C A N G+R S P+ L + + I P S I S N+ + W D+T ++ V N+ L +S + Y C+ M S LG+ +TVK+LP P + T + T++ + W YY I Y P ++ DD + L + Y IRV +N IG GP S+ + +T + P +I Q+ + + W P+ + N R+ ++ + + I HN+ + + + L + ++ A S G G + V +GV Q + + + T I W P D E + R ++ +S ++ T ++ ++ Y L + + + L ++ PS P+++ S S LVSW+P NG +T Y+V Y E E I +E +L L K+ Y I V A T VG G S P + E+ P P ++ + + T I + W ++N I G+ + Y VE + +W T + VI GL+PD Y +AA G +G S+ + K + P L + S V W P ++ DL + +++
Sbjct: 54 FVCHATGDPKPKVSWSKKGKKVNSQRIETIE--------------FDEGAGAVLRIQPLRAPRDENIYECVAENSEGEISVNARLAIIR-EDLLPPGFPNIDMGPQLKVVERTRTATMLCAASGNPDPEITWYKDFLPIDPSASNGRIKQLRSGALQIENSEETDQGKYECVASNVEGVRYSSPANLYVRELREVRRVPPRFSIPPTSQEIMPGGSVNITCVAVGSPMPYVKWMLNSEDLTPEDEM-----PVGRNV-----------LELSSVRESANYT----------CVAMSS---LGIIESVAQITVKSLPKPPG----TPVVTETTATSVTITWD--SGNPDPVSYYIIQYKAKS---PDS--KYETVDDITTTRYSIGGLYPNTEYEIRVSAINTIGQGPPSEPVETRTGEQAPASPPRNVNGQILPQNTMMVTWEEPE--------EPNGQIKGYRVYYTMDASQPMSNWHI--HNVQDSVITTIRSLTPLETYTIKVLAFTSVGDGPFSPPIKVKVVQGVPGQPSKFQVGAVSDTSIELIWEP--------------AHDKEAIRR------YELRYRESNHGNQMKKTFDPTKSYVVESLRPNTEYYFSLAAISDKGIGAFTNEILQKTL----QAKPSAPPQEIECSSTSSTSLLVSWRPPPLKSQNGDLTGYKVLYQVVSPSEGAGGDPQPTEEPMIPPTEEQVLLQRLGKWTQYHITVSAATVVGLGPESEP--IICRTDEDVPGAPPRRVEVDVLNSTAIKVMWRSLTPGKQN---GQIRGYQVHYVRVENGESRGLPLIKDVMLADAQW--ETDDTAEYEMVIGGLKPDTTYSITVAAYTTKG-DGARSKPKLVVTKG----AVPGPPYLSVAQNSKTSAVVHWDPPDLTNGMDLQGYRLQFG 870 HSP 5 Score: 77.0258 bits (188), Expect = 2.022e-13 Identity = 140/627 (22.33%), Postives = 240/627 (38.28%), Query Frame = 1
Query: 913 ITSYPISPNSLIIERFASDNVEISWRSGLNDVTEQENFILHYREVPENITEKQIMSKFVYLTISEKKSIYKYNLKDLFPFTTYCIWMESENPLGVSPPTIALTVKTLPTSPQLSPRSITATSISNTAILVAWRPPERKF--GKFKYYQIIY-----TNNDGFLPQHWRQFAVK--DDNVMLTHLIASELYHIRVKIVNEIGHGPLSKTISIKTIAGTLSQCPDFKITEIFQS-HIKLQWGTPDPVKLFKLIQYNLLCWDVRLKIVNATAKSSTLFPILNHNLSMN---------EMEYVLY-LKNEKEIKCRLSAINSDGKGMPTEIQASTVNKGVNYQNLIHIDKIGSTYITFQWRPPSKFSFDYFLWIYQIFDSEKLDRAVKLPKIKINISDSASAENGWFVYNYTNAFSSSRYILGLRYLCRDSTDILREYVHRSDLVSTMKSVPSDSPKDLVVKEIDSNSALVSWKPLDQVHSNGIITHYEVRYY-APKKEESTERFINVSETSAILSNLK-YFHYVIYVRAFTKVGGGSWSNPKNYYRQNLEEFPIPTTIKGERKSETEINISWELPVLSEKNLAHAAIEGFIILYAPVESSPKWIKYTVQSKNLSAVIKGLEPDLRYQFQI 2727
+ P P+ + + ++E+ W +D + L YRE K+ T KS Y ++ L P T Y + + + G+ T + KTL P P+ I +S S+T++LV+WRPP K G Y+++Y + G PQ + + ++ V+L L YHI V +G GP S+ I +T P ++ S IK+ W + P K I+ ++ V S P++ + + E E V+ LK + ++A + G G ++ + V + + + T W PP + L Y++ + R P + + Y+ N + Y+ + R E V +S ++ P P+ + S L+SW P NG+IT Y + Y A E E ++ S +S +L++LK Y + +RA T VG G +S P Y + +P + ++T + + W+ SE++ IE YA K V ++ L A IKGL + Y+F++
Sbjct: 514 VQGVPGQPSKFQVGAVSDTSIELIWEPA-HDKEAIRRYELRYRESNHGNQMKK--------TFDPTKS---YVVESLRPNTEYYFSLAAISDKGIGAFTNEILQKTLQAKPSAPPQEIECSSTSSTSLLVSWRPPPLKSQNGDLTGYKVLYQVVSPSEGAGGDPQPTEEPMIPPTEEQVLLQRLGKWTQYHITVSAATVVGLGPESEPIICRTDEDVPGAPPRRVEVDVLNSTAIKVMWRSLTPGKQNGQIR------GYQVHYVRVENGESRGLPLIKDVMLADAQWETDDTAEYEMVIGGLKPDTTYSITVAAYTTKGDGARSKPKLVVTKGAVPGPPYLSVAQNSKTSAVVHWDPPD-LTNGMDLQGYRL----QFGRKDITPLATLEFAPQERR------YSVDNIHRGATYLFKMAAKSRGG--FGEEAVAE---LSVPENTPGGYPQIKEGSNVTCCSVLLSWSPPVLAERNGVITEYTLVYKEAGTGEIPRELRLHPSLSSYVLNSLKPNSAYEVKMRAHTSVGPGPYSPPIQYRTVAIHPADVPKNFTVKWATKTTVVLGWK---FSERSPYKCVIE-----YA-------HQKKDVDARELKAFIKGLRHNTTYEFKV 1091
BLAST of Protein tyrosine phosphatase receptor type D vs. Planmine SMEST
Match: SMESG000053906.1 (SMESG000053906.1) HSP 1 Score: 3762.62 bits (9756), Expect = 0.000e+0 Identity = 1845/1848 (99.84%), Postives = 1847/1848 (99.95%), Query Frame = 1
Query: 298 ENDEAPKISLIIQSPNVLLFKSMILACSSTGHPVPSISWKINESPIEELKSPLKKLQNPPRIFSIKNYQNSVLVITQLIESDSNSVLICEAENNAGFDSRQQQLKVISTETDIPSGFPVFQNNFFPIIKPYNSNVTLVCQAYGNPPPLIQWFKNYELINESFTKIKILNDGNLLLVQVTREDKGIYHCQAQNTNGLRLSDPSTLDITSYPISPNSLIIERFASDNVEISWRSGLNDVTEQENFILHYREVPENITEKQIMSKFVYLTISEKKSIYKYNLKDLFPFTTYCIWMESENPLGVSPPTIALTVKTLPTSPQLSPRSITATSISNTAILVAWRPPERKFGKFKYYQIIYTNNDGFLPQHWRQFAVKDDNVMLTHLIASELYHIRVKIVNEIGHGPLSKTISIKTIAGTLSQCPDFKITEIFQSHIKLQWGTPDPVKLFKLIQYNLLCWDVRLKIVNATAKSSTLFPILNHNLSMNEMEYVLYLKNEKEIKCRLSAINSDGKGMPTEIQASTVNKGVNYQNLIHIDKIGSTYITFQWRPPSKFSFDYFLWIYQIFDSEKLDRAVKLPKIKINISDSASAENGWFVYNYTNAFSSSRYILGLRYLCRDSTDILREYVHRSDLVSTMKSVPSDSPKDLVVKEIDSNSALVSWKPLDQVHSNGIITHYEVRYYAPKKEESTERFINVSETSAILSNLKYFHYVIYVRAFTKVGGGSWSNPKNYYRQNLEEFPIPTTIKGERKSETEINISWELPVLSEKNLAHAAIEGFIILYAPVESSPKWIKYTVQSKNLSAVIKGLEPDLRYQFQIAATNYAGFNGNFSEIVQEMPKNFPNLNLKTVPDLRCSVQSSNRLKVEWSSPSISTDLLKFEIRYSGNLSYITEIGLKKSEFIDMESKSVNFETLVNRYDVTLENLQSNALYKIAVRAIYQNKELYESHRETTCDTMPAVPNLVKPPIIVGLDEEKSKVIIKLHRCSQRNGKISYYFVIVAAFQGNKNQQISFQEDTESYTFMELSVNTRSNNAKGEYIAIMKDINDIFKVSGKDHSSVLLGDGTHDENHLSVNKKLEKNFNYRCFARVCLKYSNNSLCKSSPWSEPFRISDLILNRNVXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXASIIIGCIVKRKKSKERFMHLGNHDDIRSSIGMKSSMLNGLMAADKIFVSAEVDEPFNSDKKYTSMSLKPDIKSIPDLVNADSVQMCQDGTKLSPVLVSDSIKLRIGSQKSENISDRPSISICNLYQYVTDLKANDCTLLQAEFETLNTNLDDRFTWQRSNIDSNKSKNRYANVVAYDHTSVLLTPVDDVIGSDYINANYIDGYQRQNAYIATQGPLPDTTDDFWRMVWEQRSNCIVMMTRLEERSGIKCHQYWPNRGFICYGQMIVSHIDTFVLAYYTIRLFEIRHSKYSEKREIQHFQFTAWPDHGVPKLSTPLLMFIRRVRSIGKIESCPKIVHCSAGVGRTGAFIVVDAQLERIKQEKNIDVFNYVSKIRCQRNYMVQTQAQYQFILETLLEAVEDGNTEVMACNFHAHVTKLSQIGISGSNQLSGFEMEFSKLNSLASNRGRHGVMLADFVKAAGNQAVNMTKNRVRNIIPYEWNRVVLNAIRGIEGSDYINASYIDGYRDRRAYIAAQSPIPSTVEDFWRMLWDQHCGVVIVLNQPHEDKSHIYWPINKSIRYQFFVVDPVVEYNMPNYILREFKVTDARDGEFRALRQFQFTQWPNHGCPKESESILDFIRQVHKTKEQFGHMEPMVIHCNTGSGRTGVFIALSIVLDRLQQESVVDMYQTVKLLHKQRIGLVQTEEQYEFCYMAVLDYLSNYEKILEKSHLY 5841
++ EAPKISLIIQSPNVLLFKSMILACSSTGHPVPSISWKINESPIEELKSPLKKLQNPPRIFSIKNYQNSVLVITQLIESDSNSVLICEAENNAGFDSRQQQLKVISTETDIPSGFPVFQNNFFPIIKPYNSNVTLVCQAYGNPPPLIQWFKNYELINESFTKIKILNDGNLLLVQVTREDKGIYHCQAQNTNGLRLSDPSTLDITSYPISPNSLIIERFASDNVEISWRSGLNDVTEQENFILHYREVPENITEKQIMSKFVYLTISEKKSIYKYNLKDLFPFTTYCIWMESENPLGVSPPTIALTVKTLPTSPQLSPRSITATSISNTAILVAWRPPERKFGKFKYYQIIYTNNDGFLPQHWRQFAVKDDNVMLTHLIASELYHIRVKIVNEIGHGPLSKTISIKTIAGTLSQCPDFKITEIFQSHIKLQWGTPDPVKLFKLIQYNLLCWDVRLKIVNATAKSSTLFPILNHNLSMNEMEYVLYLKNEKEIKCRLSAINSDGKGMPTEIQASTVNKGVNYQNLIHIDKIGSTYITFQWRPPSKFSFDYFLWIYQIFDSEKLDRAVKLPKIKINISDSASAENGWFVYNYTNAFSSSRYILGLRYLCRDSTDILREYVHRSDLVSTMKSVPSDSPKDLVVKEIDSNSALVSWKPLDQVHSNGIITHYEVRYYAPKKEESTERFINVSETSAILSNLKYFHYVIYVRAFTKVGGGSWSNPKNYYRQNLEEFPIPTTIKGERKSETEINISWELPVLSEKNLAHAAIEGFIILYAPVESSPKWIKYTVQSKNLSAVIKGLEPDLRYQFQIAATNYAGFNGNFSEIVQEMPKNFPNLNLKTVPDLRCSVQSSNRLKVEWSSPSISTDLLKFEIRYSGNLSYITEIGLKKSEFIDMESKSVNFETLVNRYDVTLENLQSNALYKIAVRAIYQNKELYESHRETTCDTMPAVPNLVKPPIIVGLDEEKSKVIIKLHRCSQRNGKISYYFVIVAAFQGNKNQQISFQEDTESYTFMELSVNTRSNNAKGEYIAIMKDINDIFKVSGKDHSSVLLGDGTHDENHLSVNKKLEKNFNYRCFARVCLKYSNNSLCKSSPWSEPFRISDLILNRNVSLSSSKSSKDSYSNSSIIIILLVCGVILAVASIIIGCIVKRKKSKERFMHLGNHDDIRSSIGMKSSMLNGLMAADKIFVSAEVDEPFNSDKKYTSMSLKPDIKSIPDLVNADSVQMCQDGTKLSPVLVSDSIKLRIGSQKSENISDRPSISICNLYQYVTDLKANDCTLLQAEFETLNTNLDDRFTWQRSNIDSNKSKNRYANVVAYDHTSVLLTPVDDVIGSDYINANYIDGYQRQNAYIATQGPLPDTTDDFWRMVWEQRSNCIVMMTRLEERSGIKCHQYWPNRGFICYGQMIVSHIDTFVLAYYTIRLFEIRHSKYSEKREIQHFQFTAWPDHGVPKLSTPLLMFIRRVRSIGKIESCPKIVHCSAGVGRTGAFIVVDAQLERIKQEKNIDVFNYVSKIRCQRNYMVQTQAQYQFILETLLEAVEDGNTEVMACNFHAHVTKLSQIGISGSNQLSGFEMEFSKLNSLASNRGRHGVMLADFVKAAGNQAVNMTKNRVRNIIPYEWNRVVLNAIRGIEGSDYINASYIDGYRDRRAYIAAQSPIPSTVEDFWRMLWDQHCGVVIVLNQPHEDKSHIYWPINKSIRYQFFVVDPVVEYNMPNYILREFKVTDARDGEFRALRQFQFTQWPNHGCPKESESILDFIRQVHKTKEQFGHMEPMVIHCNTGSGRTGVFIALSIVLDRLQQESVVDMYQTVKLLHKQRIGLVQTEEQYEFCYMAVLDYLSNYEKILEKSHLY
Sbjct: 36 KHKEAPKISLIIQSPNVLLFKSMILACSSTGHPVPSISWKINESPIEELKSPLKKLQNPPRIFSIKNYQNSVLVITQLIESDSNSVLICEAENNAGFDSRQQQLKVISTETDIPSGFPVFQNNFFPIIKPYNSNVTLVCQAYGNPPPLIQWFKNYELINESFTKIKILNDGNLLLVQVTREDKGIYHCQAQNTNGLRLSDPSTLDITSYPISPNSLIIERFASDNVEISWRSGLNDVTEQENFILHYREVPENITEKQIMSKFVYLTISEKKSIYKYNLKDLFPFTTYCIWMESENPLGVSPPTIALTVKTLPTSPQLSPRSITATSISNTAILVAWRPPERKFGKFKYYQIIYTNNDGFLPQHWRQFAVKDDNVMLTHLIASELYHIRVKIVNEIGHGPLSKTISIKTIAGTLSQCPDFKITEIFQSHIKLQWGTPDPVKLFKLIQYNLLCWDVRLKIVNATAKSSTLFPILNHNLSMNEMEYVLYLKNEKEIKCRLSAINSDGKGMPTEIQASTVNKGVNYQNLIHIDKIGSTYITFQWRPPSKFSFDYFLWIYQIFDSEKLDRAVKLPKIKINISDSASAENGWFVYNYTNAFSSSRYILGLRYLCRDSTDILREYVHRSDLVSTMKSVPSDSPKDLVVKEIDSNSALVSWKPLDQVHSNGIITHYEVRYYAPKKEESTERFINVSETSAILSNLKYFHYVIYVRAFTKVGGGSWSNPKNYYRQNLEEFPIPTTIKGERKSETEINISWELPVLSEKNLAHAAIEGFIILYAPVESSPKWIKYTVQSKNLSAVIKGLEPDLRYQFQIAATNYAGFNGNFSEIVQEMPKNFPNLNLKTVPDLRCSVQSSNRLKVEWSSPSISTDLLKFEIRYSGNLSYITEIGLKKSEFIDMESKSVNFETLVNRYDVTLENLQSNALYKIAVRAIYQNKELYESHRETTCDTMPAVPNLVKPPIIVGLDEEKSKVIIKLHRCSQRNGKISYYFVIVAAFQGNKNQQISFQEDTESYTFMELSVNTRSNNAKGEYIAIMKDINDIFKVSGKDHSSVLLGDGTHDENHLSVNKKLEKNFNYRCFARVCLKYSNNSLCKSSPWSEPFRISDLILNRNVSLSSSKSSKDSYSNSSIIIILLVCGVILAVASIIIGCIVKRKKSKERFMHLGNHDDIRSSIGMKSSMLNGLMAADKIFVSAEVDEPFNSDKKYTSMSLKPDIKSIPDLVNADSVQMCQDGTKLSPVLVSDSIKLRIGSQKSENISDRPSISICNLYQYVTDLKANDCTLLQAEFETLNTNLDDRFTWQRSNIDSNKSKNRYANVVAYDHTSVLLTPVDDVIGSDYINANYIDGYQRQNAYIATQGPLPDTTDDFWRMVWEQRSNCIVMMTRLEERSGIKCHQYWPNRGFICYGQMIVSHIDTFVLAYYTIRLFEIRHSKYSEKREIQHFQFTAWPDHGVPKLSTPLLMFIRRVRSIGKIESCPKIVHCSAGVGRTGAFIVVDAQLERIKQEKNIDVFNYVSKIRCQRNYMVQTQAQYQFILETLLEAVEDGNTEVMACNFHAHVTKLSQIGISGSNQLSGFEMEFSKLNSLASNRGRHGVMLADFVKAAGNQAVNMTKNRVRNIIPYEWNRVVLNAIRGIEGSDYINASYIDGYRDRRAYIAAQSPIPSTVEDFWRMLWDQHCGVVIVLNQPHEDKSHIYWPINKSIRYQFFVVDPVVEYNMPNYILREFKVTDARDGEFRALRQFQFTQWPNHGCPKESESILDFIRQVHKTKEQFGHMEPMVIHCNTGSGRTGVFIALSIVLDRLQQESVVDMYQTVKLLHKQRIGLVQTEEQYEFCYMAVLDYLSNYEKILEKSHLY 1883
BLAST of Protein tyrosine phosphatase receptor type D vs. Planmine SMEST
Match: SMESG000053906.1 (SMESG000053906.1) HSP 1 Score: 3759.92 bits (9749), Expect = 0.000e+0 Identity = 1845/1848 (99.84%), Postives = 1847/1848 (99.95%), Query Frame = 1
Query: 298 ENDEAPKISLIIQSPNVLLFKSMILACSSTGHPVPSISWKINESPIEELKSPLKKLQNPPRIFSIKNYQNSVLVITQLIESDSNSVLICEAENNAGFDSRQQQLKVISTETDIPSGFPVFQNNFFPIIKPYNSNVTLVCQAYGNPPPLIQWFKNYELINESFTKIKILNDGNLLLVQVTREDKGIYHCQAQNTNGLRLSDPSTLDITSYPISPNSLIIERFASDNVEISWRSGLNDVTEQENFILHYREVPENITEKQIMSKFVYLTISEKKSIYKYNLKDLFPFTTYCIWMESENPLGVSPPTIALTVKTLPTSPQLSPRSITATSISNTAILVAWRPPERKFGKFKYYQIIYTNNDGFLPQHWRQFAVKDDNVMLTHLIASELYHIRVKIVNEIGHGPLSKTISIKTIAGTLSQCPDFKITEIFQSHIKLQWGTPDPVKLFKLIQYNLLCWDVRLKIVNATAKSSTLFPILNHNLSMNEMEYVLYLKNEKEIKCRLSAINSDGKGMPTEIQASTVNKGVNYQNLIHIDKIGSTYITFQWRPPSKFSFDYFLWIYQIFDSEKLDRAVKLPKIKINISDSASAENGWFVYNYTNAFSSSRYILGLRYLCRDSTDILREYVHRSDLVSTMKSVPSDSPKDLVVKEIDSNSALVSWKPLDQVHSNGIITHYEVRYYAPKKEESTERFINVSETSAILSNLKYFHYVIYVRAFTKVGGGSWSNPKNYYRQNLEEFPIPTTIKGERKSETEINISWELPVLSEKNLAHAAIEGFIILYAPVESSPKWIKYTVQSKNLSAVIKGLEPDLRYQFQIAATNYAGFNGNFSEIVQEMPKNFPNLNLKTVPDLRCSVQSSNRLKVEWSSPSISTDLLKFEIRYSGNLSYITEIGLKKSEFIDMESKSVNFETLVNRYDVTLENLQSNALYKIAVRAIYQNKELYESHRETTCDTMPAVPNLVKPPIIVGLDEEKSKVIIKLHRCSQRNGKISYYFVIVAAFQGNKNQQISFQEDTESYTFMELSVNTRSNNAKGEYIAIMKDINDIFKVSGKDHSSVLLGDGTHDENHLSVNKKLEKNFNYRCFARVCLKYSNNSLCKSSPWSEPFRISDLILNRNVXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXASIIIGCIVKRKKSKERFMHLGNHDDIRSSIGMKSSMLNGLMAADKIFVSAEVDEPFNSDKKYTSMSLKPDIKSIPDLVNADSVQMCQDGTKLSPVLVSDSIKLRIGSQKSENISDRPSISICNLYQYVTDLKANDCTLLQAEFETLNTNLDDRFTWQRSNIDSNKSKNRYANVVAYDHTSVLLTPVDDVIGSDYINANYIDGYQRQNAYIATQGPLPDTTDDFWRMVWEQRSNCIVMMTRLEERSGIKCHQYWPNRGFICYGQMIVSHIDTFVLAYYTIRLFEIRHSKYSEKREIQHFQFTAWPDHGVPKLSTPLLMFIRRVRSIGKIESCPKIVHCSAGVGRTGAFIVVDAQLERIKQEKNIDVFNYVSKIRCQRNYMVQTQAQYQFILETLLEAVEDGNTEVMACNFHAHVTKLSQIGISGSNQLSGFEMEFSKLNSLASNRGRHGVMLADFVKAAGNQAVNMTKNRVRNIIPYEWNRVVLNAIRGIEGSDYINASYIDGYRDRRAYIAAQSPIPSTVEDFWRMLWDQHCGVVIVLNQPHEDKSHIYWPINKSIRYQFFVVDPVVEYNMPNYILREFKVTDARDGEFRALRQFQFTQWPNHGCPKESESILDFIRQVHKTKEQFGHMEPMVIHCNTGSGRTGVFIALSIVLDRLQQESVVDMYQTVKLLHKQRIGLVQTEEQYEFCYMAVLDYLSNYEKILEKSHLY 5841
++ EAPKISLIIQSPNVLLFKSMILACSSTGHPVPSISWKINESPIEELKSPLKKLQNPPRIFSIKNYQNSVLVITQLIESDSNSVLICEAENNAGFDSRQQQLKVISTETDIPSGFPVFQNNFFPIIKPYNSNVTLVCQAYGNPPPLIQWFKNYELINESFTKIKILNDGNLLLVQVTREDKGIYHCQAQNTNGLRLSDPSTLDITSYPISPNSLIIERFASDNVEISWRSGLNDVTEQENFILHYREVPENITEKQIMSKFVYLTISEKKSIYKYNLKDLFPFTTYCIWMESENPLGVSPPTIALTVKTLPTSPQLSPRSITATSISNTAILVAWRPPERKFGKFKYYQIIYTNNDGFLPQHWRQFAVKDDNVMLTHLIASELYHIRVKIVNEIGHGPLSKTISIKTIAGTLSQCPDFKITEIFQSHIKLQWGTPDPVKLFKLIQYNLLCWDVRLKIVNATAKSSTLFPILNHNLSMNEMEYVLYLKNEKEIKCRLSAINSDGKGMPTEIQASTVNKGVNYQNLIHIDKIGSTYITFQWRPPSKFSFDYFLWIYQIFDSEKLDRAVKLPKIKINISDSASAENGWFVYNYTNAFSSSRYILGLRYLCRDSTDILREYVHRSDLVSTMKSVPSDSPKDLVVKEIDSNSALVSWKPLDQVHSNGIITHYEVRYYAPKKEESTERFINVSETSAILSNLKYFHYVIYVRAFTKVGGGSWSNPKNYYRQNLEEFPIPTTIKGERKSETEINISWELPVLSEKNLAHAAIEGFIILYAPVESSPKWIKYTVQSKNLSAVIKGLEPDLRYQFQIAATNYAGFNGNFSEIVQEMPKNFPNLNLKTVPDLRCSVQSSNRLKVEWSSPSISTDLLKFEIRYSGNLSYITEIGLKKSEFIDMESKSVNFETLVNRYDVTLENLQSNALYKIAVRAIYQNKELYESHRETTCDTMPAVPNLVKPPIIVGLDEEKSKVIIKLHRCSQRNGKISYYFVIVAAFQGNKNQQISFQEDTESYTFMELSVNTRSNNAKGEYIAIMKDINDIFKVSGKDHSSVLLGDGTHDENHLSVNKKLEKNFNYRCFARVCLKYSNNSLCKSSPWSEPFRISDLILNRNVSLSSSKSSKDSYSNSSIIIILLVCGVILAVASIIIGCIVKRKKSKERFMHLGNHDDIRSSIGMKSSMLNGLMAADKIFVSAEVDEPFNSDKKYTSMSLKPDIKSIPDLVNADSVQMCQDGTKLSPVLVSDSIKLRIGSQKSENISDRPSISICNLYQYVTDLKANDCTLLQAEFETLNTNLDDRFTWQRSNIDSNKSKNRYANVVAYDHTSVLLTPVDDVIGSDYINANYIDGYQRQNAYIATQGPLPDTTDDFWRMVWEQRSNCIVMMTRLEERSGIKCHQYWPNRGFICYGQMIVSHIDTFVLAYYTIRLFEIRHSKYSEKREIQHFQFTAWPDHGVPKLSTPLLMFIRRVRSIGKIESCPKIVHCSAGVGRTGAFIVVDAQLERIKQEKNIDVFNYVSKIRCQRNYMVQTQAQYQFILETLLEAVEDGNTEVMACNFHAHVTKLSQIGISGSNQLSGFEMEFSKLNSLASNRGRHGVMLADFVKAAGNQAVNMTKNRVRNIIPYEWNRVVLNAIRGIEGSDYINASYIDGYRDRRAYIAAQSPIPSTVEDFWRMLWDQHCGVVIVLNQPHEDKSHIYWPINKSIRYQFFVVDPVVEYNMPNYILREFKVTDARDGEFRALRQFQFTQWPNHGCPKESESILDFIRQVHKTKEQFGHMEPMVIHCNTGSGRTGVFIALSIVLDRLQQESVVDMYQTVKLLHKQRIGLVQTEEQYEFCYMAVLDYLSNYEKILEKSHLY
Sbjct: 4 KHKEAPKISLIIQSPNVLLFKSMILACSSTGHPVPSISWKINESPIEELKSPLKKLQNPPRIFSIKNYQNSVLVITQLIESDSNSVLICEAENNAGFDSRQQQLKVISTETDIPSGFPVFQNNFFPIIKPYNSNVTLVCQAYGNPPPLIQWFKNYELINESFTKIKILNDGNLLLVQVTREDKGIYHCQAQNTNGLRLSDPSTLDITSYPISPNSLIIERFASDNVEISWRSGLNDVTEQENFILHYREVPENITEKQIMSKFVYLTISEKKSIYKYNLKDLFPFTTYCIWMESENPLGVSPPTIALTVKTLPTSPQLSPRSITATSISNTAILVAWRPPERKFGKFKYYQIIYTNNDGFLPQHWRQFAVKDDNVMLTHLIASELYHIRVKIVNEIGHGPLSKTISIKTIAGTLSQCPDFKITEIFQSHIKLQWGTPDPVKLFKLIQYNLLCWDVRLKIVNATAKSSTLFPILNHNLSMNEMEYVLYLKNEKEIKCRLSAINSDGKGMPTEIQASTVNKGVNYQNLIHIDKIGSTYITFQWRPPSKFSFDYFLWIYQIFDSEKLDRAVKLPKIKINISDSASAENGWFVYNYTNAFSSSRYILGLRYLCRDSTDILREYVHRSDLVSTMKSVPSDSPKDLVVKEIDSNSALVSWKPLDQVHSNGIITHYEVRYYAPKKEESTERFINVSETSAILSNLKYFHYVIYVRAFTKVGGGSWSNPKNYYRQNLEEFPIPTTIKGERKSETEINISWELPVLSEKNLAHAAIEGFIILYAPVESSPKWIKYTVQSKNLSAVIKGLEPDLRYQFQIAATNYAGFNGNFSEIVQEMPKNFPNLNLKTVPDLRCSVQSSNRLKVEWSSPSISTDLLKFEIRYSGNLSYITEIGLKKSEFIDMESKSVNFETLVNRYDVTLENLQSNALYKIAVRAIYQNKELYESHRETTCDTMPAVPNLVKPPIIVGLDEEKSKVIIKLHRCSQRNGKISYYFVIVAAFQGNKNQQISFQEDTESYTFMELSVNTRSNNAKGEYIAIMKDINDIFKVSGKDHSSVLLGDGTHDENHLSVNKKLEKNFNYRCFARVCLKYSNNSLCKSSPWSEPFRISDLILNRNVSLSSSKSSKDSYSNSSIIIILLVCGVILAVASIIIGCIVKRKKSKERFMHLGNHDDIRSSIGMKSSMLNGLMAADKIFVSAEVDEPFNSDKKYTSMSLKPDIKSIPDLVNADSVQMCQDGTKLSPVLVSDSIKLRIGSQKSENISDRPSISICNLYQYVTDLKANDCTLLQAEFETLNTNLDDRFTWQRSNIDSNKSKNRYANVVAYDHTSVLLTPVDDVIGSDYINANYIDGYQRQNAYIATQGPLPDTTDDFWRMVWEQRSNCIVMMTRLEERSGIKCHQYWPNRGFICYGQMIVSHIDTFVLAYYTIRLFEIRHSKYSEKREIQHFQFTAWPDHGVPKLSTPLLMFIRRVRSIGKIESCPKIVHCSAGVGRTGAFIVVDAQLERIKQEKNIDVFNYVSKIRCQRNYMVQTQAQYQFILETLLEAVEDGNTEVMACNFHAHVTKLSQIGISGSNQLSGFEMEFSKLNSLASNRGRHGVMLADFVKAAGNQAVNMTKNRVRNIIPYEWNRVVLNAIRGIEGSDYINASYIDGYRDRRAYIAAQSPIPSTVEDFWRMLWDQHCGVVIVLNQPHEDKSHIYWPINKSIRYQFFVVDPVVEYNMPNYILREFKVTDARDGEFRALRQFQFTQWPNHGCPKESESILDFIRQVHKTKEQFGHMEPMVIHCNTGSGRTGVFIALSIVLDRLQQESVVDMYQTVKLLHKQRIGLVQTEEQYEFCYMAVLDYLSNYEKILEKSHLY 1851
BLAST of Protein tyrosine phosphatase receptor type D vs. Planmine SMEST
Match: SMESG000053906.1 (SMESG000053906.1) HSP 1 Score: 2467.57 bits (6394), Expect = 0.000e+0 Identity = 1218/1223 (99.59%), Postives = 1221/1223 (99.84%), Query Frame = 1
Query: 2173 VSTMKSVPSDSPKDLVVKEIDSNSALVSWKPLDQVHSNGIITHYEVRYYAPKKEESTERFINVSETSAILSNLKYFHYVIYVRAFTKVGGGSWSNPKNYYRQNLEEFPIPTTIKGERKSETEINISWELPVLSEKNLAHAAIEGFIILYAPVESSPKWIKYTVQSKNLSAVIKGLEPDLRYQFQIAATNYAGFNGNFSEIVQEMPKNFPNLNLKTVPDLRCSVQSSNRLKVEWSSPSISTDLLKFEIRYSGNLSYITEIGLKKSEFIDMESKSVNFETLVNRYDVTLENLQSNALYKIAVRAIYQNKELYESHRETTCDTMPAVPNLVKPPIIVGLDEEKSKVIIKLHRCSQRNGKISYYFVIVAAFQGNKNQQISFQEDTESYTFMELSVNTRSNNAKGEYIAIMKDINDIFKVSGKDHSSVLLGDGTHDENHLSVNKKLEKNFNYRCFARVCLKYSNNSLCKSSPWSEPFRISDLILNRNVXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXASIIIGCIVKRKKSKERFMHLGNHDDIRSSIGMKSSMLNGLMAADKIFVSAEVDEPFNSDKKYTSMSLKPDIKSIPDLVNADSVQMCQDGTKLSPVLVSDSIKLRIGSQKSENISDRPSISICNLYQYVTDLKANDCTLLQAEFETLNTNLDDRFTWQRSNIDSNKSKNRYANVVAYDHTSVLLTPVDDVIGSDYINANYIDGYQRQNAYIATQGPLPDTTDDFWRMVWEQRSNCIVMMTRLEERSGIKCHQYWPNRGFICYGQMIVSHIDTFVLAYYTIRLFEIRHSKYSEKREIQHFQFTAWPDHGVPKLSTPLLMFIRRVRSIGKIESCPKIVHCSAGVGRTGAFIVVDAQLERIKQEKNIDVFNYVSKIRCQRNYMVQTQAQYQFILETLLEAVEDGNTEVMACNFHAHVTKLSQIGISGSNQLSGFEMEFSKLNSLASNRGRHGVMLADFVKAAGNQAVNMTKNRVRNIIPYEWNRVVLNAIRGIEGSDYINASYIDGYRDRRAYIAAQSPIPSTVEDFWRMLWDQHCGVVIVLNQPHEDKSHIYWPINKSIRYQFFVVDPVVEYNMPNYILREFKVTDARDGEFRALRQFQFTQWPNHGCPKESESILDFIRQVHKTKEQFGHMEPMVIHCNTGSGRTGVFIALSIVLDRLQQESVVDMYQTVKLLHKQRIGLVQTEEQYEFCYMAVLDYLSNYEKILEKSHLY 5841
++ +SVPSDSPKDLVVKEIDSNSALVSWKPLDQVHSNGIITHYEVRYYAPKKEESTERFINVSETSAILSNLKYFHYVIYVRAFTKVGGGSWSNPKNYYRQNLEEFPIPTTIKGERKSETEINISWELPVLSEKNLAHAAIEGFIILYAPVESSPKWIKYTVQSKNLSAVIKGLEPDLRYQFQIAATNYAGFNGNFSEIVQEMPKNFPNLNLKTVPDLRCSVQSSNRLKVEWSSPSISTDLLKFEIRYSGNLSYITEIGLKKSEFIDMESKSVNFETLVNRYDVTLENLQSNALYKIAVRAIYQNKELYESHRETTCDTMPAVPNLVKPPIIVGLDEEKSKVIIKLHRCSQRNGKISYYFVIVAAFQGNKNQQISFQEDTESYTFMELSVNTRSNNAKGEYIAIMKDINDIFKVSGKDHSSVLLGDGTHDENHLSVNKKLEKNFNYRCFARVCLKYSNNSLCKSSPWSEPFRISDLILNRNVSLSSSKSSKDSYSNSSIIIILLVCGVILAVASIIIGCIVKRKKSKERFMHLGNHDDIRSSIGMKSSMLNGLMAADKIFVSAEVDEPFNSDKKYTSMSLKPDIKSIPDLVNADSVQMCQDGTKLSPVLVSDSIKLRIGSQKSENISDRPSISICNLYQYVTDLKANDCTLLQAEFETLNTNLDDRFTWQRSNIDSNKSKNRYANVVAYDHTSVLLTPVDDVIGSDYINANYIDGYQRQNAYIATQGPLPDTTDDFWRMVWEQRSNCIVMMTRLEERSGIKCHQYWPNRGFICYGQMIVSHIDTFVLAYYTIRLFEIRHSKYSEKREIQHFQFTAWPDHGVPKLSTPLLMFIRRVRSIGKIESCPKIVHCSAGVGRTGAFIVVDAQLERIKQEKNIDVFNYVSKIRCQRNYMVQTQAQYQFILETLLEAVEDGNTEVMACNFHAHVTKLSQIGISGSNQLSGFEMEFSKLNSLASNRGRHGVMLADFVKAAGNQAVNMTKNRVRNIIPYEWNRVVLNAIRGIEGSDYINASYIDGYRDRRAYIAAQSPIPSTVEDFWRMLWDQHCGVVIVLNQPHEDKSHIYWPINKSIRYQFFVVDPVVEYNMPNYILREFKVTDARDGEFRALRQFQFTQWPNHGCPKESESILDFIRQVHKTKEQFGHMEPMVIHCNTGSGRTGVFIALSIVLDRLQQESVVDMYQTVKLLHKQRIGLVQTEEQYEFCYMAVLDYLSNYEKILEKSHLY
Sbjct: 134 ITLKESVPSDSPKDLVVKEIDSNSALVSWKPLDQVHSNGIITHYEVRYYAPKKEESTERFINVSETSAILSNLKYFHYVIYVRAFTKVGGGSWSNPKNYYRQNLEEFPIPTTIKGERKSETEINISWELPVLSEKNLAHAAIEGFIILYAPVESSPKWIKYTVQSKNLSAVIKGLEPDLRYQFQIAATNYAGFNGNFSEIVQEMPKNFPNLNLKTVPDLRCSVQSSNRLKVEWSSPSISTDLLKFEIRYSGNLSYITEIGLKKSEFIDMESKSVNFETLVNRYDVTLENLQSNALYKIAVRAIYQNKELYESHRETTCDTMPAVPNLVKPPIIVGLDEEKSKVIIKLHRCSQRNGKISYYFVIVAAFQGNKNQQISFQEDTESYTFMELSVNTRSNNAKGEYIAIMKDINDIFKVSGKDHSSVLLGDGTHDENHLSVNKKLEKNFNYRCFARVCLKYSNNSLCKSSPWSEPFRISDLILNRNVSLSSSKSSKDSYSNSSIIIILLVCGVILAVASIIIGCIVKRKKSKERFMHLGNHDDIRSSIGMKSSMLNGLMAADKIFVSAEVDEPFNSDKKYTSMSLKPDIKSIPDLVNADSVQMCQDGTKLSPVLVSDSIKLRIGSQKSENISDRPSISICNLYQYVTDLKANDCTLLQAEFETLNTNLDDRFTWQRSNIDSNKSKNRYANVVAYDHTSVLLTPVDDVIGSDYINANYIDGYQRQNAYIATQGPLPDTTDDFWRMVWEQRSNCIVMMTRLEERSGIKCHQYWPNRGFICYGQMIVSHIDTFVLAYYTIRLFEIRHSKYSEKREIQHFQFTAWPDHGVPKLSTPLLMFIRRVRSIGKIESCPKIVHCSAGVGRTGAFIVVDAQLERIKQEKNIDVFNYVSKIRCQRNYMVQTQAQYQFILETLLEAVEDGNTEVMACNFHAHVTKLSQIGISGSNQLSGFEMEFSKLNSLASNRGRHGVMLADFVKAAGNQAVNMTKNRVRNIIPYEWNRVVLNAIRGIEGSDYINASYIDGYRDRRAYIAAQSPIPSTVEDFWRMLWDQHCGVVIVLNQPHEDKSHIYWPINKSIRYQFFVVDPVVEYNMPNYILREFKVTDARDGEFRALRQFQFTQWPNHGCPKESESILDFIRQVHKTKEQFGHMEPMVIHCNTGSGRTGVFIALSIVLDRLQQESVVDMYQTVKLLHKQRIGLVQTEEQYEFCYMAVLDYLSNYEKILEKSHLY 1356
BLAST of Protein tyrosine phosphatase receptor type D vs. Planmine SMEST
Match: SMESG000053906.1 (SMESG000053906.1) HSP 1 Score: 1330.47 bits (3442), Expect = 0.000e+0 Identity = 649/649 (100.00%), Postives = 649/649 (100.00%), Query Frame = 1
Query: 244 MFWIITQLVLINSQITFTENDEAPKISLIIQSPNVLLFKSMILACSSTGHPVPSISWKINESPIEELKSPLKKLQNPPRIFSIKNYQNSVLVITQLIESDSNSVLICEAENNAGFDSRQQQLKVISTETDIPSGFPVFQNNFFPIIKPYNSNVTLVCQAYGNPPPLIQWFKNYELINESFTKIKILNDGNLLLVQVTREDKGIYHCQAQNTNGLRLSDPSTLDITSYPISPNSLIIERFASDNVEISWRSGLNDVTEQENFILHYREVPENITEKQIMSKFVYLTISEKKSIYKYNLKDLFPFTTYCIWMESENPLGVSPPTIALTVKTLPTSPQLSPRSITATSISNTAILVAWRPPERKFGKFKYYQIIYTNNDGFLPQHWRQFAVKDDNVMLTHLIASELYHIRVKIVNEIGHGPLSKTISIKTIAGTLSQCPDFKITEIFQSHIKLQWGTPDPVKLFKLIQYNLLCWDVRLKIVNATAKSSTLFPILNHNLSMNEMEYVLYLKNEKEIKCRLSAINSDGKGMPTEIQASTVNKGVNYQNLIHIDKIGSTYITFQWRPPSKFSFDYFLWIYQIFDSEKLDRAVKLPKIKINISDSASAENGWFVYNYTNAFSSSRYILGLRYLCRDSTDILREYVHRSDLVSTMKS 2190
MFWIITQLVLINSQITFTENDEAPKISLIIQSPNVLLFKSMILACSSTGHPVPSISWKINESPIEELKSPLKKLQNPPRIFSIKNYQNSVLVITQLIESDSNSVLICEAENNAGFDSRQQQLKVISTETDIPSGFPVFQNNFFPIIKPYNSNVTLVCQAYGNPPPLIQWFKNYELINESFTKIKILNDGNLLLVQVTREDKGIYHCQAQNTNGLRLSDPSTLDITSYPISPNSLIIERFASDNVEISWRSGLNDVTEQENFILHYREVPENITEKQIMSKFVYLTISEKKSIYKYNLKDLFPFTTYCIWMESENPLGVSPPTIALTVKTLPTSPQLSPRSITATSISNTAILVAWRPPERKFGKFKYYQIIYTNNDGFLPQHWRQFAVKDDNVMLTHLIASELYHIRVKIVNEIGHGPLSKTISIKTIAGTLSQCPDFKITEIFQSHIKLQWGTPDPVKLFKLIQYNLLCWDVRLKIVNATAKSSTLFPILNHNLSMNEMEYVLYLKNEKEIKCRLSAINSDGKGMPTEIQASTVNKGVNYQNLIHIDKIGSTYITFQWRPPSKFSFDYFLWIYQIFDSEKLDRAVKLPKIKINISDSASAENGWFVYNYTNAFSSSRYILGLRYLCRDSTDILREYVHRSDLVSTMKS
Sbjct: 1 MFWIITQLVLINSQITFTENDEAPKISLIIQSPNVLLFKSMILACSSTGHPVPSISWKINESPIEELKSPLKKLQNPPRIFSIKNYQNSVLVITQLIESDSNSVLICEAENNAGFDSRQQQLKVISTETDIPSGFPVFQNNFFPIIKPYNSNVTLVCQAYGNPPPLIQWFKNYELINESFTKIKILNDGNLLLVQVTREDKGIYHCQAQNTNGLRLSDPSTLDITSYPISPNSLIIERFASDNVEISWRSGLNDVTEQENFILHYREVPENITEKQIMSKFVYLTISEKKSIYKYNLKDLFPFTTYCIWMESENPLGVSPPTIALTVKTLPTSPQLSPRSITATSISNTAILVAWRPPERKFGKFKYYQIIYTNNDGFLPQHWRQFAVKDDNVMLTHLIASELYHIRVKIVNEIGHGPLSKTISIKTIAGTLSQCPDFKITEIFQSHIKLQWGTPDPVKLFKLIQYNLLCWDVRLKIVNATAKSSTLFPILNHNLSMNEMEYVLYLKNEKEIKCRLSAINSDGKGMPTEIQASTVNKGVNYQNLIHIDKIGSTYITFQWRPPSKFSFDYFLWIYQIFDSEKLDRAVKLPKIKINISDSASAENGWFVYNYTNAFSSSRYILGLRYLCRDSTDILREYVHRSDLVSTMKS 649
BLAST of Protein tyrosine phosphatase receptor type D vs. Planmine SMEST
Match: SMESG000041927.1 (SMESG000041927.1) HSP 1 Score: 762.296 bits (1967), Expect = 0.000e+0 Identity = 599/1923 (31.15%), Postives = 937/1923 (48.73%), Query Frame = 1
Query: 370 LACSSTGHPVPSISWKINESPIEELKSPLKKLQNPPRIFSIKNYQNSVLVITQLIESDSNSVLICEAENNAGFDSRQQQLKVISTETDIPSGFPVFQNNFFPIIKPYNSNVTLVCQAYGNPPPLIQWFKNYE--LINESFT-KIKILNDGNLLLVQVTREDKGIYHCQAQNTN-----------------------GLRLSDPS-TLDITSYPISPNSLIIERFASDN----VEISWRSGLNDVTEQENFILHY-REVPENITEKQIMSKFVYLTISEKKSIYKYNLKDLFPFTTYCIWMESENPLGVSPPTIALTVKTLPTSPQLSPRSITATSISNTAILVAWRPPE--RKFGKFKY---YQIIYTNNDGFLPQHWRQFAVKDD--NVMLTHLIASELYHIRVKIVNEIGHGPLSKTISIKTIAGTLSQCPDFKITEIFQSHIKLQW----GTPDPVKLFKLIQYNLLCWDVRLKIVNATAKSSTL------FPILNHNLSMNEMEYVLY-LKNEKEIKCRLSAINSDGKGMPTEIQASTVNKG---------VNYQNLIHIDKIGSTYIT--FQWRPP--SKFSFDYFLWIYQIFDSEKLDRAVKLPKIKINISDSASAENGWFVYNYTNAFSSSRY--ILGLRYLCRDSTDILREYVHRSDLVSTMKSVPSDSPKDLVVKEIDSNSALVSWKPLDQVHSNGIITHYEVRYYAPKKEESTERFINVSETSAILSNLKY-FHYVIYVRAFTKVGGGSWSNPKNYYRQNLEEFPIPTTIKGERKSETEINISWELPVLSEKNLAHAAIEGFIILYAPVESSPKWIKY--TVQSKNLSAVIKG-LEPDLRYQFQIAATNYAGFNGNFSEIVQEMPKNFPNLNLKTVPDLRCSVQSSNRLKVEWSSPSISTDLLKFEIRYSGNLSYITEIGLKKSEFIDMESKSVNFETLVNRYDVTLENLQSNALYKIAVRAIYQN---KELYESHRETTCDTMPAVPNLVKPPIIVGLDEEKSKVIIKLHRCSQRNGKISYYFVIVAAFQGNKNQQISFQEDTESYTFMELSVNTRSNNAKGEYIAIMKDINDIFKVS-------GKDHSSVLLGDGTHDENHLSVNKKL-EKNFNYRCFARVCL-----KYSNNSL--CKSSPWSEPFRISDLILNRNVXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXASIIIGCIVKRKKSKERFMHLGNHDDIRSSIGMKSSMLNGLMAADKIFVSAEVDEPFNSDKKYTSMSLKPDIKSIPDLVNADSVQMCQDGTKLSPVLVSDSIKLRIGSQKSENISDRPSISICNLYQYVTDLKANDCTLLQAEFETLNTNLDDRFTWQRSNIDSNKSKNRYANVVAYDHTSVLLTPVDDVIGSDYINANYIDGYQRQNAYIATQGPLPDTTDDFWRMVWEQRSNCIVMMTRLEERSGIKCHQYWPNRGFICYGQ--MIVSHIDTFVLAYYTIRLFEIRHSKYS------EKREIQHFQFTAWPDHGVPKLSTPLLMFIRRVRSIGKIESCPKIVHCSAGVGRTGAFIVVDAQLERIKQEKNIDVFNYVSKIRCQRNYMVQTQAQYQFILETLLEAVEDGNTEVMACNFHAHVTKLSQ----IGISGSNQLS-GFEMEFSKLNSLASNRGRHGVMLADFVKAAGNQAVNMTKNRVRNIIPYEWNRVVLNAIRGIEGSDYINASYIDGYRDRRAYIAAQSPIPSTVEDFWRMLWDQHCGVVIVLNQPHE---DKSHIYWPINKSIRYQFFVVDPVVEYNMPNYILREFKVTDARDGEF--RALRQFQFTQWPNHGCPKESESILDFIRQVHKTKEQFGHMEPMVIHCNTGSGRTGVFIALSIVLDRLQQESVVDMYQTVKLLHKQRIGLVQTEEQYEFCYMAVLDYLSNYEKIL 5823
L C++ G+P P + W + + P+ L + + S+L++T + E S IC A N+ G Q++V IP PV N+T C G I W +N E L ESFT I L+ N +L ++ I+ N N L SDPS T+ I + + P+S +A+ + + + W + + ++ ++Y R + I + Q + + + DLF TY I + + N G P + + P P P + I++T+I + W PP+ K Y Y++I + L + + D + +T L + LYHI + E G G +S T++++T + + + + I ++W + + FK+ ++LK + S+ + P N S + EY++ L+ + K L ++ S G P G + L + G T + W PP S + + + + + L ++K + + + + NY F Y + ++ DI E VST +S P P + + I S+S +SW+P + NGI+ +Y+V Y+ + +T R + A++ L+ Y VRAFTKVG G WS+ N+ L P P I+ R +E +I ++WEL S N + + GF I Y +++ PK I+ T+ ++ V G ++ + YQ I + G S I P + +V L+C + + ++++W P +L KF + +G SY E G + + + V+F ++ + L+++ N +Y I+V+ +Y+ Y + + T+C T+ A P V P I+ ++ + +++ R ++ G I Y++I+ + Q+ +F + Y+F S+ + S I + + NDIFK G+D ++ + L + + + +Y+ F R C+ ++N+ C S WS F + + +++ K + + II +++ ++A+ SI +GC +KR++ K + + ++NG + + +S V P Y +S I + + DS SIK + K+ ++ P I +L Y+ LK ND E+E+++ FTW +SN++ NK KNRYANV+AYDH+ V+L+ ++D+ GSDYINANY DGY++QNAYIATQGPLP+T + FWRMVWE R IVMMT+LEER +KC QYWP RG Y + + ++H++T LAYYT+R F + S E R++ HFQFT WPDHGVP + PLLMFI+RVRS +S P +VHCSAGVGRTGA+IV+D+QL +I+ EK +DV+ VS++R QRNYMVQT+ QY FI + LLEA GNTEV + HAHVTKL Q +G++ SNQ S G E+EF L+ L S R R F A N N KNR+ NI+PYE RV L IR +GSDYINAS+IDGYR ++AYIA Q P+ +T+ DFWRMLW + +V++L+Q E +K YWP +S + +V+P+VEYNMP++ILREF+V + D E R +RQFQF W G P+ ES++DFI QVHKTKEQFG P+ +HC+ G GRTGVF+ALSIVLDR++ E +D++QTV+LL QR +VQTE+QY+FCY+ L+YLS++++ L
Sbjct: 248 LTCTAKGNPPPQLRW------LTQYHRPINDLTD----------KESILLLTDITEPAS---YICRANNSMGVIQHAVQVRV----KKIPK-IPV--------------NIT--CLNIGPTDAQISWEQNPESDLPAESFTLMIADLSIDNTVLG--LKQIPNIHPWPPDNKNITYNVTDLRPYTKYSVKVIAFSKTLGDSDPSKTIVIETKELPPSSPPQSVYATADTFTSITVKWAPPIEANGKITDYNVYYSRNLQHPINQWQ----------KSETTRQHVRITDLFTNNTYHIKVNAVNSAGPGPVSEPFPIIVRPGVPP-QPHNFRGAGITSTSINLIWSPPQLPSKLVLLDYVLKYKVISGKHIPTLTNKEEEIKILPDRTDYRMTELWPNTLYHISLAARTEHGVG-VSNTMNVRTENRVPNSPIGIDVRTLSPTSIAIRWRKGMDNEESISSFKIKV-------IKLKSIETVDNSNEMHVQIQSVPAKTKNQS-DIYEYIINDLETGQNYKIVLWSVGSSGLSAPFIFDIVKTRPGNIVPSPPLNIRLNQLRQKTESGLTLLLADIAWDPPINSHGTIKAYRIRHNLVGPQNLIESLKRRSLSVKVYEKNVTGT-----NYCTEFGELGYGKVYEFSVAAMNTADIGLEVKLN---VSTRESAPDSYPVSIDITGITSHSVNISWQPPLVENHNGILVNYQVAYFTYGLKNTTIRTTSTPNLYALIEGLQENMLYTFQVRAFTKVGQGPWSSDVNFRTVVLLPDP-PINIEASRINENQIKVTWEL---SHTN--NIKVVGFKIYYC-LQTIPKDIESCNTLDVGPVTMVTLGNVQYNSDYQVGIKSKGIDNRYGLISNIATAKISELPVIRDLSVSSLKCEGKVRS-MEIQWQKPKTHDNLSKFRVTINGYASYTKETGEVEKFKSSFKPREVDFVDKYIKFVLGLKDMSPNMVYDISVQTVYKRDGESSFYGAIQNTSCRTLMARPKFVSTPEIILVNRTSLSIYLRILRVTEHLGIIRTYYLIIE--ESIHTQKTNFSK----YSFE--SLQSASKPISDSPILVAEFSNDIFKKGSNISFWVGQDIWRSQYSKPIYNTDSLLMRPIMFDMKKSYKMFLRACIFTEITSFANDDFYPCTDSSWSRLFNFEE-----SPAINKLLPKKQTDVFTVSIIAIIIGLGVIALISIAVGCFMKRRRPKRYYN------------SPQELIMNGDPSLKQALISQAVSGP----PSYVPLSHSNGI-----VTDMDS-----------------SIK---SNFKNTIVNKHPPIPSGHLADYIAALKTNDNAKFTEEYESIDPG--HHFTWIQSNLEINKPKNRYANVIAYDHSRVVLSTLNDIPGSDYINANYCDGYRKQNAYIATQGPLPETFEAFWRMVWESRCALIVMMTKLEERLRVKCDQYWPTRGSEAYAESGLSINHLETVELAYYTMRKFSLTKKLSSDPNGSKETRDVFHFQFTGWPDHGVPDTALPLLMFIKRVRSCCPSDSGPIVVHCSAGVGRTGAYIVLDSQLSQIQHEKVVDVYGIVSRLRAQRNYMVQTEEQYVFIYDALLEASLCGNTEVSIRHLHAHVTKLKQPLPVLGVTPSNQYSTGMELEFKHLSEL-STRPRQ------FNTA--NLPENRLKNRLINILPYENRRVCLQPIRNQDGSDYINASFIDGYRSQKAYIATQGPLANTIVDFWRMLWQHNSSIVVMLSQLREMGREKCSQYWPTERSATFGQIIVEPMVEYNMPSFILREFRVRHS-DSETHNRTIRQFQFLDWAEQGVPRSGESLIDFIGQVHKTKEQFGQEGPITVHCSAGVGRTGVFLALSIVLDRMRSEGTIDLFQTVRLLRMQRPCMVQTEDQYQFCYLTALEYLSSFDQFL 2026 HSP 2 Score: 126.331 bits (316), Expect = 1.732e-28 Identity = 203/849 (23.91%), Postives = 359/849 (42.29%), Query Frame = 1
Query: 697 NVTLVCQAYGNPPPLIQWFKNYEL-INESFTKIKILNDGNLLLVQVTREDKGIYHCQAQNTNGLRLSDPSTLDITSYPISPNSLIIERFASDNVEISWRSGLNDVTEQENFILHYREVPENITE---KQIMSKFVYLTISEKKSIYKYNLKDLFPFTTYCIWMES-ENPLGVSPPTIALTVKTLPTSPQLSPRSITATSISNTAILVAWRPPERKFGKFKYYQIIYTNNDGFLPQHWRQFAVKDDNVMLTHLIASELYHIRVKIVNEIGHGPLSKTISIKTIAGTLSQCPDFKITEIFQSHIKLQWGTPD-PVKLFKLIQYNLLCWDVRLKIVNATAKSSTLFPILNHNLSMNEMEYVLYLKNEKEIK-----------CRLSAINSDGKGMPTEIQASTVNKGVNYQNLIHIDKIGSTYITFQWRP--PSKFSFDYF-LWIYQIFDSEKLDRAVKLPKIKINISDSASAENGWFVYNY--TNAFSSSRYILGLRYLCRDSTDILREYVHRSDLVSTMKS--VPSDSPKDLVVKEIDSNS--------ALVSWKPLDQVHSNGIITHYEVRY--YAPKKE-ESTER---FINVSETSAILSN-------LKYFH-YVIYVRAFTKVGGGSWSNPKNYYRQNLEE-FPIPTTIKGERKSETEINISWELPVLSEKNLAHAAIEGFIILYAPVESSPKWIKYTVQSKNLSAVIKGLEPDLRYQFQIAATNYAGFNGNFSEIVQEMPKNFPNLNLKTV---PDLRCSVQSS----NRLKVEWS-SPSISTDLLKFEIRYSGNLSYITEIGLKKSEFIDMESKSVNFETLVNRYDVTLENLQSNALYKIAVRA 3078
V L C A GNPPP ++W Y IN+ K IL LL +T + Y C+A N+ G+ + + + P P ++ + +ISW E+F L ++ + T KQI + ++ + K+I YN+ DL P+T Y + + + LG S P+ + ++T P P+S+ AT+ + T+I V W PP GK Y + Y+ N W++ +V +T L + YHI+V VN G GP+S+ I G Q +F+ I + I L W P P KL LL + ++ K++ S P L N+ E + L + + + L+A G G+ + T N+ N I + + T I +WR ++ S F + + ++ E +D + ++ ++I S A +N +Y Y + + Y + L + S+ + ++ D+V T VPS P ++ + ++ + A ++W P ++S+G I Y +R+ P+ ES +R + V E + +N L Y Y V A G R++ + +P+ I G + +NISW+ P++ N + Y ++ + T + NL A+I+GL+ ++ Y FQ+ A G G +S ++N +TV PD ++++S N++KV W S + + ++ F+I Y + I + +S N + VTL N+Q N+ Y++ +++
Sbjct: 245 GVNLTCTAKGNPPPQLRWLTQYHRPINDLTDKESIL-----LLTDIT--EPASYICRANNSMGV-IQHAVQVRVKKIPKIPVNITCLNIGPTDAQISWEQNPESDLPAESFTLMIADLSIDNTVLGLKQIPN--IHPWPPDNKNI-TYNVTDLRPYTKYSVKVIAFSKTLGDSDPSKTIVIETKELPPSSPPQSVYATADTFTSITVKWAPPIEANGKITDYNVYYSRNLQHPINQWQKSETTRQHVRITDLFTNNTYHIKVNAVNSAGPGPVSEPFPIIVRPGVPPQPHNFRGAGITSTSINLIWSPPQLPSKLV------LLDYVLKYKVI-----SGKHIPTLT-----NKEEEIKILPDRTDYRMTELWPNTLYHISLAARTEHGVGVSNTMNVRTENRVPNSPIGIDVRTLSPTSIAIRWRKGMDNEESISSFKIKVIKLKSIETVDNSNEM-HVQIQ-SVPAKTKNQSDIYEYIINDLETGQNYKIVLWSV--GSSGLSAPFIF--DIVKTRPGNIVPS-PPLNIRLNQLRQKTESGLTLLLADIAWDP--PINSHGTIKAYRIRHNLVGPQNLIESLKRRSLSVKVYEKNVTGTNYCTEFGELGYGKVYEFSVAAMNTADIGLEVKLNVSTRESAPDSYPVSIDITG--ITSHSVNISWQPPLVENHNGILVNYQVAYFTYGLKNTTIR----TTSTPNLYALIEGLQENMLYTFQVRAFTKVG-QGPWSS----------DVNFRTVVLLPDPPINIEASRINENQIKVTWELSHTNNIKVVGFKIYYC-------------LQTIPKDIESCNTLDVGPVTMVTLGNVQYNSDYQVGIKS 1027 HSP 3 Score: 80.8777 bits (198), Expect = 1.241e-14 Identity = 233/1019 (22.87%), Postives = 395/1019 (38.76%), Query Frame = 1
Query: 244 MFW-IITQLVLINSQITFTENDEAPKISLIIQSPNVLLFKSMILACSSTGHPVPSISWKINESPIEELKSPLKKLQNPPRIFSIKNYQNSVLVITQLIESDSNSVLI-CEAENNAGFDSRQQQLKVISTETDIPSGFPVFQN--NFFPIIKPYNSNVTLVCQAYGNPPPLIQWFKNYELINESFTKIKILNDGNLLLVQVTREDKGIYHCQAQNTNGLRLSDPSTLDITSYPISPNSLIIERFASDNVEISWRSGLN-------DVTEQENFILHYREVPENITEKQIMSKFVYLTISEKKSIYKYNLKDLFPFTTYCIWMESENPLGVSPPTIALTVKTLPTSPQLSPRSITATSISNTAILVAW-RPPERKFGKFKYYQII----YTNNDGFLPQHWRQFAVKDDNVMLTHLIASELYHIR--VKIV---NEIGHGPLSKTISIKTIAGTLSQCPD--FKITEIFQSHIKLQWGTPDPVKLFKLIQYNLLCWDVRLKIVNATAKSSTLFPILNHNLSMNEMEYVLYLKNEKEIKCRLSAINSDGKGMPTEIQASTVNKGVNYQ-NLIHIDKIGSTYITFQWRP---PSKFSFDYFLWIYQIFDSEKLDRAV-KLPKIKINISDSASAENGWFVYNYTNAFSSSRYILGLRYLCRDSTDILREYVHRSDLVSTMKSVPSDSPKDLVVKEIDSNSALVSW-KPLDQVHSNGIITHYEVRYYAPKKEE----STERFINVSETSAILSNLK-YFHYVI--------YVRAFTKVGGGSWSNPKNY-----YRQNLEEFPIPTTIK-GERKSETE-------INISWELPVLSEKNLAHAAIEGFII---LYAP---VES------SPKWIKYTVQSKNLSAVIKGLEPDLRYQFQIAATNYA--GFNGNFSEIVQE-MPKNFP-NLNLKTVPDLRCSVQSSNRLKVEWSSPSISTD---LLKFEIRYSGNLSYITEIGLKKSEFIDMESKSVNFETLVNRYDVTLENLQSNALYKIAVRA 3078
+FW I L+ +++ IT T A KI + QS VLL ++ I C G+P +S L N + + I +L I + +D V I C N + + + L V D+P+GFP F++ +F+ + N+ + C G P WFK+ ++ S + +L G++ ++ +ED GIY C+ N G LS L+I + PI+P + +VE+ G+N + Q ++ Y ++T+K+ S + I+E P + C + N +GV + + VK +P P +IT +I T ++W + PE + +I N L Q DN +T+ + + + VK++ +G SKTI I+T S P + + F S I ++W P K+ YN+ +N KS T ++ + + L+ N IK ++A+NS G G +E V GV Q + I ST I W P PSK ++ Y++ + + K +IKI + D Y T + ++ Y + L V + V T VP +SP + V+ + S + W K +D S I+ ++++ K E S E + + A N + Y+I Y VG S P + N+ P P I+ + + +TE +I+W+ P+ S H I+ + I L P +ES S K + V N L Y+F +AA N A G + +E P ++P ++++ + +S+ + + W P + L+ +++ Y +Y GLK + ++ + N Y + +E LQ N LY VRA
Sbjct: 16 LFWCFILNLLYLSTNITSTG---AAKIIVAPQSQTVLLGETAIFFCQIDGNPSFHLSL----------------LYNGMKKYVIPIPSGLMLRIPDVKLTDGKPVRIDCIVRNPSAEEKKTAYLNVTDPSKDLPNGFPRFKSIKDFY--VGDVGQNMKMNCDVEGGLPIKFNWFKDNAPLDLSEPRRTMLRSGSIFFDRLLKEDSGIYECRVINPVGSILSSKMKLEIRNTPITPQWI----HRPQDVEVRPGHGVNLTCTAKGNPPPQLRWLTQYHRPINDLTDKE--SILLLTDITE-------------PASYIC---RANNSMGVIQHAVQVRVKKIPKIPV----NITCLNIGPTDAQISWEQNPESDLPAESFTLMIADLSIDNTVLGLKQIPNIHPWPPDNKNITYNVTDLRPYTKYSVKVIAFSKTLGDSDPSKTIVIETKELPPSSPPQSVYATADTFTS-ITVKWAPPIEAN-GKITDYNVYYSRNLQHPINQWQKSET----TRQHVRITD----LFTNNTYHIK--VNAVNSAGPGPVSEPFPIIVRPGVPPQPHNFRGAGITSTSINLIWSPPQLPSKLVLLDYVLKYKVISGKHIPTLTNKEEEIKI-LPDRTD-------YRMTELWPNTLYHISLAARTEHGVG-----VSNTMNVRTENRVP-NSPIGIDVRTLSPTSIAIRWRKGMDNEES---ISSFKIKVIKLKSIETVDNSNEMHVQIQSVPAKTKNQSDIYEYIINDLETGQNYKIVLWSVGSSGLSAPFIFDIVKTRPGNIVPSP-PLNIRLNQLRQKTESGLTLLLADIAWDPPINS-----HGTIKAYRIRHNLVGPQNLIESLKRRSLSVKVYEKNVTGTNYCTEFGELGYGKVYEFSVAAMNTADIGLEVKLNVSTRESAPDSYPVSIDITGI--------TSHSVNISWQPPLVENHNGILVNYQVAY---FTY----GLKNT--------TIRTTSTPNLYAL-IEGLQENMLYTFQVRA 928 The following BLAST results are available for this feature:
BLAST of Protein tyrosine phosphatase receptor type D vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of Protein tyrosine phosphatase receptor type D vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of Protein tyrosine phosphatase receptor type D vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of Protein tyrosine phosphatase receptor type D vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of Protein tyrosine phosphatase receptor type D vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of Protein tyrosine phosphatase receptor type D vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of Protein tyrosine phosphatase receptor type D vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of Protein tyrosine phosphatase receptor type D vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Protein tyrosine phosphatase receptor type D vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of Protein tyrosine phosphatase receptor type D vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 5
BLAST of Protein tyrosine phosphatase receptor type D vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 3
BLAST of Protein tyrosine phosphatase receptor type D vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of Protein tyrosine phosphatase receptor type D vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of Protein tyrosine phosphatase receptor type D vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30028312 ID=SMED30028312|Name=Protein tyrosine phosphatase receptor type D|organism=Schmidtea mediterranea sexual|type=transcript|length=5953bpback to top protein sequence of SMED30028312-orf-1 >SMED30028312-orf-1 ID=SMED30028312-orf-1|Name=SMED30028312-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=1867bp MFWIITQLVLINSQITFTENDEAPKISLIIQSPNVLLFKSMILACSSTGHback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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