S-adenosylmethionine synthase

Overview
NameS-adenosylmethionine synthase
Smed IDSMED30028293
Length (bp)1272
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of S-adenosylmethionine synthase (SMED30028293) t-SNE clustered cells

Violin plots show distribution of expression levels for S-adenosylmethionine synthase (SMED30028293) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of S-adenosylmethionine synthase (SMED30028293) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for S-adenosylmethionine synthase (SMED30028293) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30028293

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 4

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
X1 cellSMED30028293SMESG000013953.1 SmedASXL_011291SmedAsxl_ww_GCZZ01PMID:26114597
Zhu et al., 2015		FACS sorted cell population asexual adult RNA-sequencing evidence
protonephridiaSMED30028293SMESG000013953.1 dd_Smed_v4_10278_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30028293SMESG000013953.1 Contig48276newmark_estsPMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30028293SMESG000013953.1 Contig48276uc_Smed_v2PMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of S-adenosylmethionine synthase vs. Ensembl Human
Match: MAT2A (methionine adenosyltransferase 2A [Source:HGNC Symbol;Acc:HGNC:6904])

HSP 1 Score: 554.288 bits (1427), Expect = 0.000e+0
Identity = 271/382 (70.94%), Postives = 319/382 (83.51%), Query Frame = 3 
Query:   57 ENDIFLFTSESVGEGHPDKICDQISDAILDAHLKQDPYAKVACESFTKTGMVLVGGEITSHAVVNYSDIVRNTIKRIGFDSSEKGLDYRTCNVLVAIEQQSPDIAQGVYVNRSEDSIGAGDQGLMFGYATDETEECMPMTLILAHKLNQRLAYCRRNDILGWLRPDTKTQVTIAYKNKDGGLLPLYVHTIVISAQHDEEVTLENIKSDLMKHVISNVIDSKMLTSSTIYHLNPSGRFVIGGPQGDAGLTGRKIIVDTYXXXXXXXXXXXXXKDATKVDRSAAYAARWVAKSLVKNGLCKRVLVQFSYAIGIAAPLSIFVYSYNSSTKTDNELLAIVNQNFDLRPGAIIRDLKLREPIFEKTASYGHFGRNEFLWENPKKLHF 1202
            E   FLFTSESVGEGHPDKICDQISDA+LDAHL+QDP AKVACE+  KTGM+L+ GEITS A V+Y  +VR  +K IG+D S KG DY+TCNVLVA+EQQSPDIAQGV+++R+E+ IGAGDQGLMFGYATDETEECMP+T++LAHKLN +LA  RRN  L WLRPD+KTQVT+ Y    G +LP+ VHTIVIS QHDEEV L+ ++  L + VI  V+ +K L   TIYHL PSGRFVIGGPQGDAGLTGRKIIVDTYGGWGAHGGGAFSGKD TKVDRSAAYAARWVAKSLVK GLC+RVLVQ SYAIG++ PLSI ++ Y +S K++ ELL IV +NFDLRPG I+RDL L++PI+++TA+YGHFGR+ F WE PKKL +
Sbjct:   14 EEGTFLFTSESVGEGHPDKICDQISDAVLDAHLQQDPDAKVACETVAKTGMILLAGEITSRAAVDYQKVVREAVKHIGYDDSSKGFDYKTCNVLVALEQQSPDIAQGVHLDRNEEDIGAGDQGLMFGYATDETEECMPLTIVLAHKLNAKLAELRRNGTLPWLRPDSKTQVTVQYMQDRGAVLPIRVHTIVISVQHDEEVCLDEMRDALKEKVIKAVVPAKYLDEDTIYHLQPSGRFVIGGPQGDAGLTGRKIIVDTYGGWGAHGGGAFSGKDYTKVDRSAAYAARWVAKSLVKGGLCRRVLVQVSYAIGVSHPLSISIFHYGTSQKSERELLEIVKKNFDLRPGVIVRDLDLKKPIYQRTAAYGHFGRDSFPWEVPKKLKY 395
[Close]
BLAST of S-adenosylmethionine synthase vs. Ensembl Human
Match: MAT1A (methionine adenosyltransferase 1A [Source:HGNC Symbol;Acc:HGNC:6903])

HSP 1 Score: 551.977 bits (1421), Expect = 0.000e+0
Identity = 268/379 (70.71%), Postives = 326/379 (86.02%), Query Frame = 3 
Query:   66 IFLFTSESVGEGHPDKICDQISDAILDAHLKQDPYAKVACESFTKTGMVLVGGEITSHAVVNYSDIVRNTIKRIGFDSSEKGLDYRTCNVLVAIEQQSPDIAQGVYVNRSEDSIGAGDQGLMFGYATDETEECMPMTLILAHKLNQRLAYCRRNDILGWLRPDTKTQVTIAYKNKDGGLLPLYVHTIVISAQHDEEVTLENIKSDLMKHVISNVIDSKMLTSSTIYHLNPSGRFVIGGPQGDAGLTGRKIIVDTYXXXXXXXXXXXXXKDATKVDRSAAYAARWVAKSLVKNGLCKRVLVQFSYAIGIAAPLSIFVYSYNSSTKTDNELLAIVNQNFDLRPGAIIRDLKLREPIFEKTASYGHFGRNEFLWENPKKLHF 1202
            +F+FTSESVGEGHPDKICDQISDA+LDAHLKQDP AKVACE+  KTGMVL+ GEITS A+V+Y  +VR+TIK IG+D S KG D++TCNVLVA+EQQSPDIAQ V+++R+E+ +GAGDQGLMFGYATDETEECMP+T+ILAHKLN R+A  RR+ +L WLRPD+KTQVT+ Y   +G ++P+ +HTIVIS QH+E++TLE ++  L + VI  V+ +K L   T+YHL PSGRFVIGGPQGDAG+TGRKIIVDTYGGWGAHGGGAFSGKD TKVDRSAAYAARWVAKSLVK GLC+RVLVQ SYAIG+A PLSI +++Y +S KT+ ELL +V++NFDLRPG I+RDL L++PI++KTA YGHFGR+EF WE P+KL F
Sbjct:   17 VFMFTSESVGEGHPDKICDQISDAVLDAHLKQDPNAKVACETVCKTGMVLLCGEITSMAMVDYQRVVRDTIKHIGYDDSAKGFDFKTCNVLVALEQQSPDIAQCVHLDRNEEDVGAGDQGLMFGYATDETEECMPLTIILAHKLNARMADLRRSGLLPWLRPDSKTQVTVQYMQDNGAVIPVRIHTIVISVQHNEDITLEEMRRALKEQVIRAVVPAKYLDEDTVYHLQPSGRFVIGGPQGDAGVTGRKIIVDTYGGWGAHGGGAFSGKDYTKVDRSAAYAARWVAKSLVKAGLCRRVLVQVSYAIGVAEPLSISIFTYGTSQKTERELLDVVHKNFDLRPGVIVRDLDLKKPIYQKTACYGHFGRSEFPWEVPRKLVF 395
[Close]
BLAST of S-adenosylmethionine synthase vs. Ensembl Human
Match: MAT2A (methionine adenosyltransferase 2A [Source:HGNC Symbol;Acc:HGNC:6904])

HSP 1 Score: 419.468 bits (1077), Expect = 2.525e-146
Identity = 210/299 (70.23%), Postives = 247/299 (82.61%), Query Frame = 3 
Query:  207 MVLVGGEITSHAVVNYSDIVRNTIKRIGFDSSEKGLDYRTCNVLVAIEQQSPDIAQGVYVNRSEDSIGAGDQGLMFGYATDETEECMPMTLILAHKLNQRLAYCRRNDILGWLRPDTKTQVTIAYKNKDGGLLPLYVHTIVISAQHDEEVTLENIKSDLMKHVISNVIDSKMLTSSTIYHLNPSGRFVIGGPQGDAGLTGRKIIVDTYXXXXXXXXXXXXXKDATKVDRSAAYAARWVAKSLVKNGLCKRVLVQFSYAIGIAAPLSIFVYSYNSSTKTDNELLAIVNQNFDLRPGAIIR 1103
            M+L+ GEITS A V+Y  +VR  +K IG+D S KG DY+TCNVLVA+EQQSPDIAQGV+++R+E+ IGAGDQGLMFGYATDETEECMP+T++LAHKLN +LA  RRN  L WLRPD+KTQVT+ Y    G +LP+ VHTIVIS QHDEEV L+ ++  L + VI  V+ +K L   TIYHL PSGRFVIGGPQGDAGLTGRKIIVDTYGGWGAHGGGAFSGKD TKVDRSAAYAARWVAKSLVK GLC+RVLVQ SYAIG++ PLSI ++ Y +S K++ ELL IV +NFDLRPG I+R
Sbjct:    1 MILLAGEITSRAAVDYQKVVREAVKHIGYDDSSKGFDYKTCNVLVALEQQSPDIAQGVHLDRNEEDIGAGDQGLMFGYATDETEECMPLTIVLAHKLNAKLAELRRNGTLPWLRPDSKTQVTVQYMQDRGAVLPIRVHTIVISVQHDEEVCLDEMRDALKEKVIKAVVPAKYLDEDTIYHLQPSGRFVIGGPQGDAGLTGRKIIVDTYGGWGAHGGGAFSGKDYTKVDRSAAYAARWVAKSLVKGGLCRRVLVQVSYAIGVSHPLSISIFHYGTSQKSERELLEIVKKNFDLRPGVIVR 299
[Close]
BLAST of S-adenosylmethionine synthase vs. Ensembl Human
Match: MAT1A (methionine adenosyltransferase 1A [Source:HGNC Symbol;Acc:HGNC:6903])

HSP 1 Score: 221.476 bits (563), Expect = 5.499e-71
Identity = 107/186 (57.53%), Postives = 129/186 (69.35%), Query Frame = 3 
Query:   84 ESVGEGHPDKICDQISDAILDAHLKQDPYAKVACESFTKTGMVLVGGEITSHAVVNYSDIVRNTIKRIGFDSSEKGLDYRTCNVLVAIEQQSPDIAQGVYVNRSEDSIGAGDQGLMFGYATDETEECMPMTLILAHKLNQRLAYCRRNDILGWLRPDTKTQVTIAYKNKDGGLLPLYVHTIVISAQ 641
            ESVGEGHPDKICDQISDA+LDAHLKQDP AKVAC                                         G D++TCNVLVA+EQQSPDIAQ V+++R+E+ +GAGDQGLMFGYATDETEECMP+T+ILAHKLN R+A  RR+ +L WLRPD+KTQVT+ Y   +G ++P+ +HTIVIS Q
Sbjct:    1 ESVGEGHPDKICDQISDAVLDAHLKQDPNAKVAC-----------------------------------------GFDFKTCNVLVALEQQSPDIAQCVHLDRNEEDVGAGDQGLMFGYATDETEECMPLTIILAHKLNARMADLRRSGLLPWLRPDSKTQVTVQYMQDNGAVIPVRIHTIVISVQ 145
[Close]
BLAST of S-adenosylmethionine synthase vs. Ensembl Celegans
Match: sams-3 (Probable S-adenosylmethionine synthase 3 [Source:UniProtKB/Swiss-Prot;Acc:P50305])

HSP 1 Score: 523.472 bits (1347), Expect = 0.000e+0
Identity = 254/378 (67.20%), Postives = 312/378 (82.54%), Query Frame = 3 
Query:   69 FLFTSESVGEGHPDKICDQISDAILDAHLKQDPYAKVACESFTKTGMVLVGGEITSHAVVNYSDIVRNTIKRIGFDSSEKGLDYRTCNVLVAIEQQSPDIAQGVYVNRSEDSIGAGDQGLMFGYATDETEECMPMTLILAHKLNQRLAYCRRNDILGWLRPDTKTQVTIAYKNKDGGLLPLYVHTIVISAQHDEEVTLENIKSDLMKHVISNVIDSKMLTSSTIYHLNPSGRFVIGGPQGDAGLTGRKIIVDTYXXXXXXXXXXXXXKDATKVDRSAAYAARWVAKSLVKNGLCKRVLVQFSYAIGIAAPLSIFVYSYNSSTKTDNELLAIVNQNFDLRPGAIIRDLKLREPIFEKTASYGHFGRNEFLWENPKKLHF 1202
            FLFTSESV EGHPDK+CDQISDA+LDAHL QDP+AKVACE+ TKTGM+++ GEITS AVV+Y  +VRN IK+IG+D S KG DY+TCNVLVA+EQQSP+IA GV+V++  D +GAGDQG+MFGYATDETEE MP+TL+L+HKLN++L   RR+  L W+RPD+KTQVTI Y ++ G  +PL VHT+VIS QH  +++L++++ +L++ VI  VI + ++   TIYHLNP G F+IGGP GDAGLTGRKIIVDTYGGWGAHGGGAFSGKD TKVDRSAAYAARWVAKSLVK+GLC+R LVQ SYAIG+A PLS+ V+S+ +S   + ELL IVN NFDLRPG II+DL L++PI+E TA  GHFG NEF WE P+ L  
Sbjct:    6 FLFTSESVSEGHPDKMCDQISDAVLDAHLAQDPHAKVACETVTKTGMIMLCGEITSKAVVDYQVLVRNVIKKIGYDDSSKGFDYKTCNVLVALEQQSPEIAAGVHVDKDSDDVGAGDQGIMFGYATDETEEAMPLTLLLSHKLNRKLHELRRSGELEWVRPDSKTQVTIEYASEGGACVPLRVHTVVISTQHSPDISLDDLRKELIEKVIKAVIPANLIDDKTIYHLNPCGSFIIGGPMGDAGLTGRKIIVDTYGGWGAHGGGAFSGKDPTKVDRSAAYAARWVAKSLVKSGLCRRCLVQVSYAIGVAKPLSVMVFSFGTSALNEGELLKIVNDNFDLRPGMIIKDLDLKKPIYEPTAENGHFGHNEFPWEQPRHLQI 383
[Close]
BLAST of S-adenosylmethionine synthase vs. Ensembl Celegans
Match: sams-4 (Probable S-adenosylmethionine synthase 4 [Source:UniProtKB/Swiss-Prot;Acc:P50306])

HSP 1 Score: 518.079 bits (1333), Expect = 0.000e+0
Identity = 251/376 (66.76%), Postives = 310/376 (82.45%), Query Frame = 3 
Query:   69 FLFTSESVGEGHPDKICDQISDAILDAHLKQDPYAKVACESFTKTGMVLVGGEITSHAVVNYSDIVRNTIKRIGFDSSEKGLDYRTCNVLVAIEQQSPDIAQGVYVNRSEDSIGAGDQGLMFGYATDETEECMPMTLILAHKLNQRLAYCRRNDILGWLRPDTKTQVTIAYKNKDGGLLPLYVHTIVISAQHDEEVTLENIKSDLMKHVISNVIDSKMLTSSTIYHLNPSGRFVIGGPQGDAGLTGRKIIVDTYXXXXXXXXXXXXXKDATKVDRSAAYAARWVAKSLVKNGLCKRVLVQFSYAIGIAAPLSIFVYSYNSSTKTDNELLAIVNQNFDLRPGAIIRDLKLREPIFEKTASYGHFGRNEFLWENPKKL 1196
            FLFTSESV EGHPDK+CDQISDA+LDAHL QDP+AKVACE+ TKTGM+++ GEITS AVV+Y  +VRN IK+IG+D S KG DY+TCNVLVA+EQQSP+IA GV+V++  D +GAGDQG+MFGYATDETEE MP+TL+L+HKLN++L   RR+  L W+RPD+KTQVTI Y ++ G  +PL VHT+VIS QH  +++L++++ +L++ VI  VI + ++   TIYHLNP G F+IGGP GDAGLTGRKIIVDTYGGWGAHGGGAFSGKD TKVDRSAAYAARWVAKSLVK GLC+R LVQ SYAIG+A PLS+ V+S+ +S  ++ +LL IVN NFDLRPG II++L L+ PI+E TA  GHFG N F WE P+ L
Sbjct:    6 FLFTSESVSEGHPDKMCDQISDAVLDAHLAQDPHAKVACETVTKTGMIMLCGEITSKAVVDYQVLVRNVIKKIGYDDSSKGFDYKTCNVLVALEQQSPEIAAGVHVDKDSDDVGAGDQGIMFGYATDETEEAMPLTLLLSHKLNRKLHELRRSGELEWVRPDSKTQVTIEYASEGGACVPLRVHTVVISTQHSPDISLDDLRKELIEKVIKAVIPANLIDDKTIYHLNPCGSFIIGGPMGDAGLTGRKIIVDTYGGWGAHGGGAFSGKDPTKVDRSAAYAARWVAKSLVKAGLCRRCLVQVSYAIGVAKPLSVMVFSFGTSALSEEDLLTIVNDNFDLRPGKIIKNLDLKRPIYEPTAENGHFGHNNFPWEQPRNL 381
[Close]
BLAST of S-adenosylmethionine synthase vs. Ensembl Celegans
Match: sams-4 (Probable S-adenosylmethionine synthase 4 [Source:UniProtKB/Swiss-Prot;Acc:P50306])

HSP 1 Score: 518.079 bits (1333), Expect = 0.000e+0
Identity = 251/376 (66.76%), Postives = 310/376 (82.45%), Query Frame = 3 
Query:   69 FLFTSESVGEGHPDKICDQISDAILDAHLKQDPYAKVACESFTKTGMVLVGGEITSHAVVNYSDIVRNTIKRIGFDSSEKGLDYRTCNVLVAIEQQSPDIAQGVYVNRSEDSIGAGDQGLMFGYATDETEECMPMTLILAHKLNQRLAYCRRNDILGWLRPDTKTQVTIAYKNKDGGLLPLYVHTIVISAQHDEEVTLENIKSDLMKHVISNVIDSKMLTSSTIYHLNPSGRFVIGGPQGDAGLTGRKIIVDTYXXXXXXXXXXXXXKDATKVDRSAAYAARWVAKSLVKNGLCKRVLVQFSYAIGIAAPLSIFVYSYNSSTKTDNELLAIVNQNFDLRPGAIIRDLKLREPIFEKTASYGHFGRNEFLWENPKKL 1196
            FLFTSESV EGHPDK+CDQISDA+LDAHL QDP+AKVACE+ TKTGM+++ GEITS AVV+Y  +VRN IK+IG+D S KG DY+TCNVLVA+EQQSP+IA GV+V++  D +GAGDQG+MFGYATDETEE MP+TL+L+HKLN++L   RR+  L W+RPD+KTQVTI Y ++ G  +PL VHT+VIS QH  +++L++++ +L++ VI  VI + ++   TIYHLNP G F+IGGP GDAGLTGRKIIVDTYGGWGAHGGGAFSGKD TKVDRSAAYAARWVAKSLVK GLC+R LVQ SYAIG+A PLS+ V+S+ +S  ++ +LL IVN NFDLRPG II++L L+ PI+E TA  GHFG N F WE P+ L
Sbjct:    6 FLFTSESVSEGHPDKMCDQISDAVLDAHLAQDPHAKVACETVTKTGMIMLCGEITSKAVVDYQVLVRNVIKKIGYDDSSKGFDYKTCNVLVALEQQSPEIAAGVHVDKDSDDVGAGDQGIMFGYATDETEEAMPLTLLLSHKLNRKLHELRRSGELEWVRPDSKTQVTIEYASEGGACVPLRVHTVVISTQHSPDISLDDLRKELIEKVIKAVIPANLIDDKTIYHLNPCGSFIIGGPMGDAGLTGRKIIVDTYGGWGAHGGGAFSGKDPTKVDRSAAYAARWVAKSLVKAGLCRRCLVQVSYAIGVAKPLSVMVFSFGTSALSEEDLLTIVNDNFDLRPGKIIKNLDLKRPIYEPTAENGHFGHNNFPWEQPRNL 381
[Close]
BLAST of S-adenosylmethionine synthase vs. Ensembl Celegans
Match: sams-5 (Probable S-adenosylmethionine synthase 5 [Source:UniProtKB/Swiss-Prot;Acc:Q27522])

HSP 1 Score: 508.834 bits (1309), Expect = 1.942e-180
Identity = 250/376 (66.49%), Postives = 307/376 (81.65%), Query Frame = 3 
Query:   69 FLFTSESVGEGHPDKICDQISDAILDAHLKQDPYAKVACESFTKTGMVLVGGEITSHAVVNYSDIVRNTIKRIGFDSSEKGLDYRTCNVLVAIEQQSPDIAQGVYVNRSEDSIGAGDQGLMFGYATDETEECMPMTLILAHKLNQRLAYCRRNDILGWLRPDTKTQVTIAYKNKDGGLLPLYVHTIVISAQHDEEVTLENIKSDLMKHVISNVIDSKMLTSSTIYHLNPSGRFVIGGPQGDAGLTGRKIIVDTYXXXXXXXXXXXXXKDATKVDRSAAYAARWVAKSLVKNGLCKRVLVQFSYAIGIAAPLSIFVYSYNSSTKTDNELLAIVNQNFDLRPGAIIRDLKLREPIFEKTASYGHFGRNEFLWENPKKL 1196
            FLFTSESV EGHPDK+CDQISDA+LDAHL QDP+AKVACE+ TKTGM+++ GEITS AVV+Y  +VRN IK+IG+D S KG DY+TCNVLVA+EQQSP+IA GV+V++    +GAGDQG+MFGYATDETEE MP+TL+L+HKLN +L   RR+  L W+RPD+KTQVTI Y ++ G  +PL VHT+VIS QH  +++LE+++ +L++ VI  VI   ++ + T+YHLNP G FV+GGP GDAGLTGRKIIVDTYGGWGAHGGGAFSGKD TKVDRSAAYAARWVAKSLVK GLC+R LVQ SYAIG+A PLS+ V+S+ +S   + ELL IVN NFDLRPG II++L L+  I+E TA  GHFG N+F WE  +KL
Sbjct:    6 FLFTSESVSEGHPDKMCDQISDAVLDAHLAQDPHAKVACETVTKTGMIMLCGEITSKAVVDYQVLVRNVIKKIGYDDSSKGFDYKTCNVLVALEQQSPEIAAGVHVDKDIADVGAGDQGIMFGYATDETEEAMPLTLLLSHKLNYKLHELRRSGELEWVRPDSKTQVTIEYSSEGGACVPLRVHTVVISTQHSPDISLEDLRKELIEKVIKVVIPGNLIDNDTVYHLNPCGSFVVGGPMGDAGLTGRKIIVDTYGGWGAHGGGAFSGKDPTKVDRSAAYAARWVAKSLVKAGLCRRCLVQVSYAIGVAKPLSVMVFSFGTSALNEAELLKIVNDNFDLRPGMIIKNLDLKRAIYEPTAENGHFGHNDFPWEQARKL 381
[Close]
BLAST of S-adenosylmethionine synthase vs. Ensembl Celegans
Match: sams-5 (Probable S-adenosylmethionine synthase 5 [Source:UniProtKB/Swiss-Prot;Acc:Q27522])

HSP 1 Score: 508.834 bits (1309), Expect = 1.942e-180
Identity = 250/376 (66.49%), Postives = 307/376 (81.65%), Query Frame = 3 
Query:   69 FLFTSESVGEGHPDKICDQISDAILDAHLKQDPYAKVACESFTKTGMVLVGGEITSHAVVNYSDIVRNTIKRIGFDSSEKGLDYRTCNVLVAIEQQSPDIAQGVYVNRSEDSIGAGDQGLMFGYATDETEECMPMTLILAHKLNQRLAYCRRNDILGWLRPDTKTQVTIAYKNKDGGLLPLYVHTIVISAQHDEEVTLENIKSDLMKHVISNVIDSKMLTSSTIYHLNPSGRFVIGGPQGDAGLTGRKIIVDTYXXXXXXXXXXXXXKDATKVDRSAAYAARWVAKSLVKNGLCKRVLVQFSYAIGIAAPLSIFVYSYNSSTKTDNELLAIVNQNFDLRPGAIIRDLKLREPIFEKTASYGHFGRNEFLWENPKKL 1196
            FLFTSESV EGHPDK+CDQISDA+LDAHL QDP+AKVACE+ TKTGM+++ GEITS AVV+Y  +VRN IK+IG+D S KG DY+TCNVLVA+EQQSP+IA GV+V++    +GAGDQG+MFGYATDETEE MP+TL+L+HKLN +L   RR+  L W+RPD+KTQVTI Y ++ G  +PL VHT+VIS QH  +++LE+++ +L++ VI  VI   ++ + T+YHLNP G FV+GGP GDAGLTGRKIIVDTYGGWGAHGGGAFSGKD TKVDRSAAYAARWVAKSLVK GLC+R LVQ SYAIG+A PLS+ V+S+ +S   + ELL IVN NFDLRPG II++L L+  I+E TA  GHFG N+F WE  +KL
Sbjct:    6 FLFTSESVSEGHPDKMCDQISDAVLDAHLAQDPHAKVACETVTKTGMIMLCGEITSKAVVDYQVLVRNVIKKIGYDDSSKGFDYKTCNVLVALEQQSPEIAAGVHVDKDIADVGAGDQGIMFGYATDETEEAMPLTLLLSHKLNYKLHELRRSGELEWVRPDSKTQVTIEYSSEGGACVPLRVHTVVISTQHSPDISLEDLRKELIEKVIKVVIPGNLIDNDTVYHLNPCGSFVVGGPMGDAGLTGRKIIVDTYGGWGAHGGGAFSGKDPTKVDRSAAYAARWVAKSLVKAGLCRRCLVQVSYAIGVAKPLSVMVFSFGTSALNEAELLKIVNDNFDLRPGMIIKNLDLKRAIYEPTAENGHFGHNDFPWEQARKL 381
[Close]
BLAST of S-adenosylmethionine synthase vs. Ensembl Fly
Match: Sam-S (gene:FBgn0005278 transcript:FBtr0089430)

HSP 1 Score: 515.383 bits (1326), Expect = 0.000e+0
Identity = 256/382 (67.02%), Postives = 316/382 (82.72%), Query Frame = 3 
Query:   51 MDENDIFLFTSESVGEGHPDKICDQISDAILDAHLKQDPYAKVACESFTKTGMVLVGGEITSHAVVNYSDIVRNTIKRIGFDSSEKGLDYRTCNVLVAIEQQSPDIAQGVYVNRSEDSIGAGDQGLMFGYATDETEECMPMTLILAHKLNQRLAYCRRNDILGWLRPDTKTQVTIAYKNKDGGLLPLYVHTIVISAQHDEEVTLENIKSDLMKHVISNVIDSKMLTSSTIYHLNPSGRFVIGGPQGDAGLTGRKIIVDTYXXXXXXXXXXXXXKDATKVDRSAAYAARWVAKSLVKNGLCKRVLVQFSYAIGIAAPLSIFVYSYNSSTKTDNELLAIVNQNFDLRPGAIIRDLKLREPIFEKTASYGHFGRNEFLWENPKKL 1196
            M++   FLFTSESVGEGHPDK+CDQISDAILDAHLKQDP AKVACE+  KTGM+L+ GEITS AVV+Y  +VR T++ IG+D S KG D++TCNVL+A++QQSP+IA GV+VNR+E+ IGAGDQG+MFGYATDETEECMP+T++LAHKLN+++A  RR+D+  W RPD+KTQVT  Y    G  +P  VHTIV+S QH E+++LE ++S++M+ V+  VI +K + ++TI H+NP G FVIGGP GDAGLTGRKIIVDTYGGWGAHGGGAFSGKD TKVDRSAAYAARWVAKSLVK GLCKR LVQ SYAIG+A PLSI V+ Y +S K+  ELL I+ +NFDLRPG I++DL LR+PI+++T++YGHFGR  F WE  K L
Sbjct:   23 MEDGATFLFTSESVGEGHPDKMCDQISDAILDAHLKQDPNAKVACETVAKTGMILLCGEITSKAVVDYQKVVRETVQHIGYDDSSKGFDFKTCNVLLALDQQSPEIAAGVHVNRAEEEIGAGDQGIMFGYATDETEECMPLTVVLAHKLNEKIAELRRSDVFWWARPDSKTQVTCEYLFNQGSAVPKRVHTIVVSMQHSEKISLETLRSEVMEKVVKVVIPAKYIDANTIVHINPCGLFVIGGPMGDAGLTGRKIIVDTYGGWGAHGGGAFSGKDFTKVDRSAAYAARWVAKSLVKAGLCKRCLVQVSYAIGLAEPLSITVFDYGTSHKSQKELLDIIRRNFDLRPGKIVKDLNLRQPIYQRTSTYGHFGRAGFSWEEAKPL 404
[Close]
BLAST of S-adenosylmethionine synthase vs. Ensembl Fly
Match: Sam-S (gene:FBgn0005278 transcript:FBtr0089433)

HSP 1 Score: 515.383 bits (1326), Expect = 0.000e+0
Identity = 256/382 (67.02%), Postives = 316/382 (82.72%), Query Frame = 3 
Query:   51 MDENDIFLFTSESVGEGHPDKICDQISDAILDAHLKQDPYAKVACESFTKTGMVLVGGEITSHAVVNYSDIVRNTIKRIGFDSSEKGLDYRTCNVLVAIEQQSPDIAQGVYVNRSEDSIGAGDQGLMFGYATDETEECMPMTLILAHKLNQRLAYCRRNDILGWLRPDTKTQVTIAYKNKDGGLLPLYVHTIVISAQHDEEVTLENIKSDLMKHVISNVIDSKMLTSSTIYHLNPSGRFVIGGPQGDAGLTGRKIIVDTYXXXXXXXXXXXXXKDATKVDRSAAYAARWVAKSLVKNGLCKRVLVQFSYAIGIAAPLSIFVYSYNSSTKTDNELLAIVNQNFDLRPGAIIRDLKLREPIFEKTASYGHFGRNEFLWENPKKL 1196
            M++   FLFTSESVGEGHPDK+CDQISDAILDAHLKQDP AKVACE+  KTGM+L+ GEITS AVV+Y  +VR T++ IG+D S KG D++TCNVL+A++QQSP+IA GV+VNR+E+ IGAGDQG+MFGYATDETEECMP+T++LAHKLN+++A  RR+D+  W RPD+KTQVT  Y    G  +P  VHTIV+S QH E+++LE ++S++M+ V+  VI +K + ++TI H+NP G FVIGGP GDAGLTGRKIIVDTYGGWGAHGGGAFSGKD TKVDRSAAYAARWVAKSLVK GLCKR LVQ SYAIG+A PLSI V+ Y +S K+  ELL I+ +NFDLRPG I++DL LR+PI+++T++YGHFGR  F WE  K L
Sbjct:   23 MEDGATFLFTSESVGEGHPDKMCDQISDAILDAHLKQDPNAKVACETVAKTGMILLCGEITSKAVVDYQKVVRETVQHIGYDDSSKGFDFKTCNVLLALDQQSPEIAAGVHVNRAEEEIGAGDQGIMFGYATDETEECMPLTVVLAHKLNEKIAELRRSDVFWWARPDSKTQVTCEYLFNQGSAVPKRVHTIVVSMQHSEKISLETLRSEVMEKVVKVVIPAKYIDANTIVHINPCGLFVIGGPMGDAGLTGRKIIVDTYGGWGAHGGGAFSGKDFTKVDRSAAYAARWVAKSLVKAGLCKRCLVQVSYAIGLAEPLSITVFDYGTSHKSQKELLDIIRRNFDLRPGKIVKDLNLRQPIYQRTSTYGHFGRAGFSWEEAKPL 404
[Close]
BLAST of S-adenosylmethionine synthase vs. Ensembl Fly
Match: Sam-S (gene:FBgn0005278 transcript:FBtr0089432)

HSP 1 Score: 515.383 bits (1326), Expect = 0.000e+0
Identity = 256/382 (67.02%), Postives = 316/382 (82.72%), Query Frame = 3 
Query:   51 MDENDIFLFTSESVGEGHPDKICDQISDAILDAHLKQDPYAKVACESFTKTGMVLVGGEITSHAVVNYSDIVRNTIKRIGFDSSEKGLDYRTCNVLVAIEQQSPDIAQGVYVNRSEDSIGAGDQGLMFGYATDETEECMPMTLILAHKLNQRLAYCRRNDILGWLRPDTKTQVTIAYKNKDGGLLPLYVHTIVISAQHDEEVTLENIKSDLMKHVISNVIDSKMLTSSTIYHLNPSGRFVIGGPQGDAGLTGRKIIVDTYXXXXXXXXXXXXXKDATKVDRSAAYAARWVAKSLVKNGLCKRVLVQFSYAIGIAAPLSIFVYSYNSSTKTDNELLAIVNQNFDLRPGAIIRDLKLREPIFEKTASYGHFGRNEFLWENPKKL 1196
            M++   FLFTSESVGEGHPDK+CDQISDAILDAHLKQDP AKVACE+  KTGM+L+ GEITS AVV+Y  +VR T++ IG+D S KG D++TCNVL+A++QQSP+IA GV+VNR+E+ IGAGDQG+MFGYATDETEECMP+T++LAHKLN+++A  RR+D+  W RPD+KTQVT  Y    G  +P  VHTIV+S QH E+++LE ++S++M+ V+  VI +K + ++TI H+NP G FVIGGP GDAGLTGRKIIVDTYGGWGAHGGGAFSGKD TKVDRSAAYAARWVAKSLVK GLCKR LVQ SYAIG+A PLSI V+ Y +S K+  ELL I+ +NFDLRPG I++DL LR+PI+++T++YGHFGR  F WE  K L
Sbjct:   23 MEDGATFLFTSESVGEGHPDKMCDQISDAILDAHLKQDPNAKVACETVAKTGMILLCGEITSKAVVDYQKVVRETVQHIGYDDSSKGFDFKTCNVLLALDQQSPEIAAGVHVNRAEEEIGAGDQGIMFGYATDETEECMPLTVVLAHKLNEKIAELRRSDVFWWARPDSKTQVTCEYLFNQGSAVPKRVHTIVVSMQHSEKISLETLRSEVMEKVVKVVIPAKYIDANTIVHINPCGLFVIGGPMGDAGLTGRKIIVDTYGGWGAHGGGAFSGKDFTKVDRSAAYAARWVAKSLVKAGLCKRCLVQVSYAIGLAEPLSITVFDYGTSHKSQKELLDIIRRNFDLRPGKIVKDLNLRQPIYQRTSTYGHFGRAGFSWEEAKPL 404
[Close]
BLAST of S-adenosylmethionine synthase vs. Ensembl Fly
Match: Sam-S (gene:FBgn0005278 transcript:FBtr0089429)

HSP 1 Score: 515.383 bits (1326), Expect = 0.000e+0
Identity = 256/382 (67.02%), Postives = 316/382 (82.72%), Query Frame = 3 
Query:   51 MDENDIFLFTSESVGEGHPDKICDQISDAILDAHLKQDPYAKVACESFTKTGMVLVGGEITSHAVVNYSDIVRNTIKRIGFDSSEKGLDYRTCNVLVAIEQQSPDIAQGVYVNRSEDSIGAGDQGLMFGYATDETEECMPMTLILAHKLNQRLAYCRRNDILGWLRPDTKTQVTIAYKNKDGGLLPLYVHTIVISAQHDEEVTLENIKSDLMKHVISNVIDSKMLTSSTIYHLNPSGRFVIGGPQGDAGLTGRKIIVDTYXXXXXXXXXXXXXKDATKVDRSAAYAARWVAKSLVKNGLCKRVLVQFSYAIGIAAPLSIFVYSYNSSTKTDNELLAIVNQNFDLRPGAIIRDLKLREPIFEKTASYGHFGRNEFLWENPKKL 1196
            M++   FLFTSESVGEGHPDK+CDQISDAILDAHLKQDP AKVACE+  KTGM+L+ GEITS AVV+Y  +VR T++ IG+D S KG D++TCNVL+A++QQSP+IA GV+VNR+E+ IGAGDQG+MFGYATDETEECMP+T++LAHKLN+++A  RR+D+  W RPD+KTQVT  Y    G  +P  VHTIV+S QH E+++LE ++S++M+ V+  VI +K + ++TI H+NP G FVIGGP GDAGLTGRKIIVDTYGGWGAHGGGAFSGKD TKVDRSAAYAARWVAKSLVK GLCKR LVQ SYAIG+A PLSI V+ Y +S K+  ELL I+ +NFDLRPG I++DL LR+PI+++T++YGHFGR  F WE  K L
Sbjct:   23 MEDGATFLFTSESVGEGHPDKMCDQISDAILDAHLKQDPNAKVACETVAKTGMILLCGEITSKAVVDYQKVVRETVQHIGYDDSSKGFDFKTCNVLLALDQQSPEIAAGVHVNRAEEEIGAGDQGIMFGYATDETEECMPLTVVLAHKLNEKIAELRRSDVFWWARPDSKTQVTCEYLFNQGSAVPKRVHTIVVSMQHSEKISLETLRSEVMEKVVKVVIPAKYIDANTIVHINPCGLFVIGGPMGDAGLTGRKIIVDTYGGWGAHGGGAFSGKDFTKVDRSAAYAARWVAKSLVKAGLCKRCLVQVSYAIGLAEPLSITVFDYGTSHKSQKELLDIIRRNFDLRPGKIVKDLNLRQPIYQRTSTYGHFGRAGFSWEEAKPL 404
[Close]
BLAST of S-adenosylmethionine synthase vs. Ensembl Fly
Match: Sam-S (gene:FBgn0005278 transcript:FBtr0089434)

HSP 1 Score: 515.383 bits (1326), Expect = 0.000e+0
Identity = 256/382 (67.02%), Postives = 316/382 (82.72%), Query Frame = 3 
Query:   51 MDENDIFLFTSESVGEGHPDKICDQISDAILDAHLKQDPYAKVACESFTKTGMVLVGGEITSHAVVNYSDIVRNTIKRIGFDSSEKGLDYRTCNVLVAIEQQSPDIAQGVYVNRSEDSIGAGDQGLMFGYATDETEECMPMTLILAHKLNQRLAYCRRNDILGWLRPDTKTQVTIAYKNKDGGLLPLYVHTIVISAQHDEEVTLENIKSDLMKHVISNVIDSKMLTSSTIYHLNPSGRFVIGGPQGDAGLTGRKIIVDTYXXXXXXXXXXXXXKDATKVDRSAAYAARWVAKSLVKNGLCKRVLVQFSYAIGIAAPLSIFVYSYNSSTKTDNELLAIVNQNFDLRPGAIIRDLKLREPIFEKTASYGHFGRNEFLWENPKKL 1196
            M++   FLFTSESVGEGHPDK+CDQISDAILDAHLKQDP AKVACE+  KTGM+L+ GEITS AVV+Y  +VR T++ IG+D S KG D++TCNVL+A++QQSP+IA GV+VNR+E+ IGAGDQG+MFGYATDETEECMP+T++LAHKLN+++A  RR+D+  W RPD+KTQVT  Y    G  +P  VHTIV+S QH E+++LE ++S++M+ V+  VI +K + ++TI H+NP G FVIGGP GDAGLTGRKIIVDTYGGWGAHGGGAFSGKD TKVDRSAAYAARWVAKSLVK GLCKR LVQ SYAIG+A PLSI V+ Y +S K+  ELL I+ +NFDLRPG I++DL LR+PI+++T++YGHFGR  F WE  K L
Sbjct:   23 MEDGATFLFTSESVGEGHPDKMCDQISDAILDAHLKQDPNAKVACETVAKTGMILLCGEITSKAVVDYQKVVRETVQHIGYDDSSKGFDFKTCNVLLALDQQSPEIAAGVHVNRAEEEIGAGDQGIMFGYATDETEECMPLTVVLAHKLNEKIAELRRSDVFWWARPDSKTQVTCEYLFNQGSAVPKRVHTIVVSMQHSEKISLETLRSEVMEKVVKVVIPAKYIDANTIVHINPCGLFVIGGPMGDAGLTGRKIIVDTYGGWGAHGGGAFSGKDFTKVDRSAAYAARWVAKSLVKAGLCKRCLVQVSYAIGLAEPLSITVFDYGTSHKSQKELLDIIRRNFDLRPGKIVKDLNLRQPIYQRTSTYGHFGRAGFSWEEAKPL 404
[Close]
BLAST of S-adenosylmethionine synthase vs. Ensembl Zebrafish
Match: mat2aa (methionine adenosyltransferase II, alpha a [Source:ZFIN;Acc:ZDB-GENE-030131-2049])

HSP 1 Score: 553.518 bits (1425), Expect = 0.000e+0
Identity = 268/382 (70.16%), Postives = 322/382 (84.29%), Query Frame = 3 
Query:   57 ENDIFLFTSESVGEGHPDKICDQISDAILDAHLKQDPYAKVACESFTKTGMVLVGGEITSHAVVNYSDIVRNTIKRIGFDSSEKGLDYRTCNVLVAIEQQSPDIAQGVYVNRSEDSIGAGDQGLMFGYATDETEECMPMTLILAHKLNQRLAYCRRNDILGWLRPDTKTQVTIAYKNKDGGLLPLYVHTIVISAQHDEEVTLENIKSDLMKHVISNVIDSKMLTSSTIYHLNPSGRFVIGGPQGDAGLTGRKIIVDTYXXXXXXXXXXXXXKDATKVDRSAAYAARWVAKSLVKNGLCKRVLVQFSYAIGIAAPLSIFVYSYNSSTKTDNELLAIVNQNFDLRPGAIIRDLKLREPIFEKTASYGHFGRNEFLWENPKKLHF 1202
            + D FLFTSESVGEGHPDKICDQISDA+LDAHLKQDP AKVACE+  KTGM+L+ GEITSHAVV+Y  +VR+TIK IG+D S KG DY+TCNVLVA+EQQSPDIAQGV+++R+E+ +GAGDQGLMFGYATDETEECMP+T++LAHKLN ++A  RRN  L WLRPD+KTQVT+ Y+   G +LP+ VHTIV+S QHD+ V L+ ++  L + V+  V+ +  L   TIYHL PSGRFVIGGPQGDAGLTGRKIIVDTYGGWGAHGGGAFSGKD TKVDRSAAYAARWVAKSLVK GLCKRVLVQ SYAIG+A PLS+ ++ Y +S +++ ELL IV +NFDLRPG I+R+L L++PI+++TA+YGHFGR  F WE PKKL +
Sbjct:   14 DEDCFLFTSESVGEGHPDKICDQISDAVLDAHLKQDPDAKVACETVAKTGMILLAGEITSHAVVDYQKVVRDTIKHIGYDDSSKGFDYKTCNVLVALEQQSPDIAQGVHLDRNEEDVGAGDQGLMFGYATDETEECMPLTIVLAHKLNAKMAELRRNGTLPWLRPDSKTQVTVQYRQDRGAMLPVRVHTIVVSVQHDDVVCLDEMRDALKEKVVKAVVPNVYLDDDTIYHLQPSGRFVIGGPQGDAGLTGRKIIVDTYGGWGAHGGGAFSGKDYTKVDRSAAYAARWVAKSLVKAGLCKRVLVQVSYAIGVAHPLSVSIFHYGTSQRSEKELLEIVKKNFDLRPGVIVRELDLKKPIYQRTAAYGHFGRESFPWEVPKKLKY 395
[Close]
BLAST of S-adenosylmethionine synthase vs. Ensembl Zebrafish
Match: mat1a (methionine adenosyltransferase I, alpha [Source:ZFIN;Acc:ZDB-GENE-030131-6127])

HSP 1 Score: 545.814 bits (1405), Expect = 0.000e+0
Identity = 269/376 (71.54%), Postives = 319/376 (84.84%), Query Frame = 3 
Query:   69 FLFTSESVGEGHPDKICDQISDAILDAHLKQDPYAKVACESFTKTGMVLVGGEITSHAVVNYSDIVRNTIKRIGFDSSEKGLDYRTCNVLVAIEQQSPDIAQGVYVNRSEDSIGAGDQGLMFGYATDETEECMPMTLILAHKLNQRLAYCRRNDILGWLRPDTKTQVTIAYKNKDGGLLPLYVHTIVISAQHDEEVTLENIKSDLMKHVISNVIDSKMLTSSTIYHLNPSGRFVIGGPQGDAGLTGRKIIVDTYXXXXXXXXXXXXXKDATKVDRSAAYAARWVAKSLVKNGLCKRVLVQFSYAIGIAAPLSIFVYSYNSSTKTDNELLAIVNQNFDLRPGAIIRDLKLREPIFEKTASYGHFGRNEFLWENPKKL 1196
            F+FTSESVGEGHPDKICDQISDA+LDAHLKQDP AKVACE+  KTGMVL+ GEITS A V+Y  IVR+TIK IG+D+SEKG DY+TCNVLVA+EQQSPDIAQGV+V+R E+ IGAGDQGLMFGYATDETEECMP+T++LAHKLN ++A  RR+  + WLRPD+KTQVT+ YK ++G ++PL VHT+VIS QHD+ ++LE  +  L + VI  V+ ++ L   T+YHL PSGRFVIGGPQGDAG+TGRKIIVDTYGGWGAHGGGAFSGKD TKVDRSAAYAARWVAKSLVK+ LC+RVLVQ SYAIG+A PLSI +++Y SS KT+ ELL IVN+NFDLRPG I+RDL L+ P ++ TA YGHFGR+EF WE  K L
Sbjct:   13 FMFTSESVGEGHPDKICDQISDAVLDAHLKQDPDAKVACETVCKTGMVLLCGEITSRANVDYQKIVRDTIKHIGYDNSEKGFDYKTCNVLVALEQQSPDIAQGVHVDRHEEDIGAGDQGLMFGYATDETEECMPLTIVLAHKLNSKMAELRRDGTIPWLRPDSKTQVTVHYKQENGAVIPLRVHTVVISVQHDDNISLEEQQRILKEKVIKAVVPARYLDDKTVYHLQPSGRFVIGGPQGDAGVTGRKIIVDTYGGWGAHGGGAFSGKDYTKVDRSAAYAARWVAKSLVKSKLCRRVLVQVSYAIGVAHPLSISLFTYGSSEKTEKELLHIVNKNFDLRPGVIVRDLNLKRPFYQNTACYGHFGRSEFPWEMAKTL 388
[Close]
BLAST of S-adenosylmethionine synthase vs. Ensembl Zebrafish
Match: mat1a (methionine adenosyltransferase I, alpha [Source:ZFIN;Acc:ZDB-GENE-030131-6127])

HSP 1 Score: 545.814 bits (1405), Expect = 0.000e+0
Identity = 269/376 (71.54%), Postives = 319/376 (84.84%), Query Frame = 3 
Query:   69 FLFTSESVGEGHPDKICDQISDAILDAHLKQDPYAKVACESFTKTGMVLVGGEITSHAVVNYSDIVRNTIKRIGFDSSEKGLDYRTCNVLVAIEQQSPDIAQGVYVNRSEDSIGAGDQGLMFGYATDETEECMPMTLILAHKLNQRLAYCRRNDILGWLRPDTKTQVTIAYKNKDGGLLPLYVHTIVISAQHDEEVTLENIKSDLMKHVISNVIDSKMLTSSTIYHLNPSGRFVIGGPQGDAGLTGRKIIVDTYXXXXXXXXXXXXXKDATKVDRSAAYAARWVAKSLVKNGLCKRVLVQFSYAIGIAAPLSIFVYSYNSSTKTDNELLAIVNQNFDLRPGAIIRDLKLREPIFEKTASYGHFGRNEFLWENPKKL 1196
            F+FTSESVGEGHPDKICDQISDA+LDAHLKQDP AKVACE+  KTGMVL+ GEITS A V+Y  IVR+TIK IG+D+SEKG DY+TCNVLVA+EQQSPDIAQGV+V+R E+ IGAGDQGLMFGYATDETEECMP+T++LAHKLN ++A  RR+  + WLRPD+KTQVT+ YK ++G ++PL VHT+VIS QHD+ ++LE  +  L + VI  V+ ++ L   T+YHL PSGRFVIGGPQGDAG+TGRKIIVDTYGGWGAHGGGAFSGKD TKVDRSAAYAARWVAKSLVK+ LC+RVLVQ SYAIG+A PLSI +++Y SS KT+ ELL IVN+NFDLRPG I+RDL L+ P ++ TA YGHFGR+EF WE  K L
Sbjct:   13 FMFTSESVGEGHPDKICDQISDAVLDAHLKQDPDAKVACETVCKTGMVLLCGEITSRANVDYQKIVRDTIKHIGYDNSEKGFDYKTCNVLVALEQQSPDIAQGVHVDRHEEDIGAGDQGLMFGYATDETEECMPLTIVLAHKLNSKMAELRRDGTIPWLRPDSKTQVTVHYKQENGAVIPLRVHTVVISVQHDDNISLEEQQRILKEKVIKAVVPARYLDDKTVYHLQPSGRFVIGGPQGDAGVTGRKIIVDTYGGWGAHGGGAFSGKDYTKVDRSAAYAARWVAKSLVKSKLCRRVLVQVSYAIGVAHPLSISLFTYGSSEKTEKELLHIVNKNFDLRPGVIVRDLNLKRPFYQNTACYGHFGRSEFPWEMAKTL 388
[Close]
BLAST of S-adenosylmethionine synthase vs. Ensembl Zebrafish
Match: mat2ab (methionine adenosyltransferase II, alpha b [Source:ZFIN;Acc:ZDB-GENE-050327-6])

HSP 1 Score: 508.449 bits (1308), Expect = 1.293e-180
Identity = 251/349 (71.92%), Postives = 292/349 (83.67%), Query Frame = 3 
Query:   57 ENDIFLFTSESVGEGHPDKICDQISDAILDAHLKQDPYAKVACESFTKTGMVLVGGEITSHAVVNYSDIVRNTIKRIGFDSSEKGLDYRTCNVLVAIEQQSPDIAQGVYVNRSEDSIGAGDQGLMFGYATDETEECMPMTLILAHKLNQRLAYCRRNDILGWLRPDTKTQVTIAYKNKDGGLLPLYVHTIVISAQHDEEVTLENIKSDLMKHVISNVIDSKMLTSSTIYHLNPSGRFVIGGPQGDAGLTGRKIIVDTYXXXXXXXXXXXXXKDATKVDRSAAYAARWVAKSLVKNGLCKRVLVQFSYAIGIAAPLSIFVYSYNSSTKTDNELLAIVNQNFDLRPGAIIR 1103
            E D FLFTSESVGEGHPDKICDQISDA+LDAHLKQDP AKVACE+  KTGM+L+ GE+TS AVV+Y  +VR+TIK IG+D S KG DY+TCNVLVA+EQQSPDIAQGV++ R E  +GAGDQGLMFGYATDETEECMP+T++LAHKLN ++A  RRN  L WLRPD+KTQVT+ Y+ + G +LP+ VHTIVIS QHDE++ L+ ++  L   VI+ V+ S  L   TIYHL PSGRFVIGGPQGDAGLTGRKIIVDTYGGWGAHGGGAFSGKD TKVDRSAAYAARWVAKSLVK  LC+RVLVQ SYAIG+A PLSI ++ Y +S K++ ELL IV +NFDLRPG I+R
Sbjct:   15 EEDCFLFTSESVGEGHPDKICDQISDAVLDAHLKQDPDAKVACETVAKTGMILLAGEVTSRAVVDYQKVVRDTIKHIGYDDSTKGFDYKTCNVLVALEQQSPDIAQGVHLERDEQDVGAGDQGLMFGYATDETEECMPLTIVLAHKLNSKMAELRRNGTLPWLRPDSKTQVTVQYRQEHGAMLPIRVHTIVISVQHDEDICLDEMRDALKDKVINTVVPSMYLDDDTIYHLQPSGRFVIGGPQGDAGLTGRKIIVDTYGGWGAHGGGAFSGKDYTKVDRSAAYAARWVAKSLVKAKLCRRVLVQVSYAIGVAHPLSISIFHYGTSQKSEQELLKIVKKNFDLRPGVIVR 363
[Close]
BLAST of S-adenosylmethionine synthase vs. Ensembl Zebrafish
Match: mat2al (methionine adenosyltransferase II, alpha-like [Source:ZFIN;Acc:ZDB-GENE-060421-5255])

HSP 1 Score: 490.345 bits (1261), Expect = 4.891e-173
Identity = 238/378 (62.96%), Postives = 304/378 (80.42%), Query Frame = 3 
Query:   69 FLFTSESVGEGHPDKICDQISDAILDAHLKQDPYAKVACESFTKTGMVLVGGEITSHAVVNYSDIVRNTIKRIGFDSSEKGLDYRTCNVLVAIEQQSPDIAQGVYVNRSEDSIGAGDQGLMFGYATDETEECMPMTLILAHKLNQRLAYCRRNDILGWLRPDTKTQVTIAYKNKDGGLLPLYVHTIVISAQHDEEVTLENIKSDLMKHVISNVIDSKMLTSSTIYHLNPSGRFVIGGPQGDAGLTGRKIIVDTYXXXXXXXXXXXXXKDATKVDRSAAYAARWVAKSLVKNGLCKRVLVQFSYAIGIAAPLSIFVYSYNSSTKTDNELLAIVNQNFDLRPGAIIRDLKLREPIFEKTASYGHFGRNEFLWENPKKLHF 1202
            FLFTSESVGEGH DK+CDQISDA+LDA+L QDP ++VACE  +KTGM+L+ GE+TS AVV+   +VR+T+K IG+D S KG DY+TCNVLV+++ Q  +I+  V+  R  + IGAGDQGLMFGYATDETEECMP+T++LAHKLN ++    +  +  W+ PD+KTQVT+ Y++  G + P+ VHT+VIS QH  ++TLE+I+ +LM+ V+  VI +K L   TIYHL PSG+F++GGPQGDAGLTGRKIIVDTYGGWG HGGGAFSGKD +KVDRS AYAARWVAKSLVK  LC+RVLVQ SYAIGI+ PLS+ V+ Y +ST+ +++LL IV +NFDLRPG I+++L L++PI++KTA YGHFGR  F WE PKKL F
Sbjct:   13 FLFTSESVGEGHSDKMCDQISDAVLDAYLTQDPDSRVACECVSKTGMILLCGEVTSKAVVDLQRVVRDTVKTIGYDDSSKGFDYKTCNVLVSLQPQVSEISDCVFEGRDSEDIGAGDQGLMFGYATDETEECMPLTILLAHKLNYKMKELSKTGVCPWILPDSKTQVTVEYRDNMGAMEPVRVHTVVISVQHSPDITLEDIRHNLMEKVVKAVIPAKYLDDKTIYHLLPSGKFLLGGPQGDAGLTGRKIIVDTYGGWGGHGGGAFSGKDYSKVDRSGAYAARWVAKSLVKAKLCRRVLVQISYAIGISHPLSVSVFHYGTSTRDEDDLLEIVKKNFDLRPGVIVKELDLKKPIYQKTACYGHFGREGFPWEKPKKLIF 390
[Close]
BLAST of S-adenosylmethionine synthase vs. Ensembl Xenopus
Match: mat1a (methionine adenosyltransferase I, alpha [Source:NCBI gene;Acc:100127858])

HSP 1 Score: 555.444 bits (1430), Expect = 0.000e+0
Identity = 272/378 (71.96%), Postives = 322/378 (85.19%), Query Frame = 3 
Query:   69 FLFTSESVGEGHPDKICDQISDAILDAHLKQDPYAKVACESFTKTGMVLVGGEITSHAVVNYSDIVRNTIKRIGFDSSEKGLDYRTCNVLVAIEQQSPDIAQGVYVNRSEDSIGAGDQGLMFGYATDETEECMPMTLILAHKLNQRLAYCRRNDILGWLRPDTKTQVTIAYKNKDGGLLPLYVHTIVISAQHDEEVTLENIKSDLMKHVISNVIDSKMLTSSTIYHLNPSGRFVIGGPQGDAGLTGRKIIVDTYXXXXXXXXXXXXXKDATKVDRSAAYAARWVAKSLVKNGLCKRVLVQFSYAIGIAAPLSIFVYSYNSSTKTDNELLAIVNQNFDLRPGAIIRDLKLREPIFEKTASYGHFGRNEFLWENPKKLHF 1202
            F+FTSESVGEGHPDKICDQISDA+LDAHL QDP AKVACE+  KTGMVL+ GEITS AVV+Y  IVR+TIK IG+D SEKG DY+TCNVLVA+EQQSPDIAQGV+++R+E+ IGAGDQGLMFGYATDETEECMP+T++LAHKLN +LA  RRN +L WLRPD+KTQVT+ Y  K+G ++P+ VHTIVIS QHDE ++L +++  L +HVI  V+ +K L   T+YHL PSGRFVIGGPQGDAG+TGRKIIVDTYGGWGAHGGGAFSGKD TKVDRSAAYAARWVAKSLV   LC RVLVQ SYAIG+A PLS+ +++Y +S KT+ ELL IVN NFDLRPG I+RDL L++P+++KTA YGHFGR +F WE PK+L F
Sbjct:   19 FMFTSESVGEGHPDKICDQISDAVLDAHLSQDPDAKVACETVCKTGMVLLCGEITSRAVVDYQKIVRDTIKYIGYDDSEKGFDYKTCNVLVALEQQSPDIAQGVHLDRTEEDIGAGDQGLMFGYATDETEECMPLTIVLAHKLNSKLAELRRNGVLPWLRPDSKTQVTVKYIQKNGAVIPVRVHTIVISVQHDETISLSDMQEALKEHVIKAVVPAKYLDEKTVYHLQPSGRFVIGGPQGDAGVTGRKIIVDTYGGWGAHGGGAFSGKDYTKVDRSAAYAARWVAKSLVHAKLCHRVLVQVSYAIGVAYPLSVSLFTYGTSEKTEKELLDIVNANFDLRPGVIVRDLDLKKPLYQKTACYGHFGREDFPWEVPKELFF 396
[Close]
BLAST of S-adenosylmethionine synthase vs. Ensembl Xenopus
Match: use1 (unconventional SNARE in the ER 1 homolog [Source:Xenbase;Acc:XB-GENE-972033])

HSP 1 Score: 548.895 bits (1413), Expect = 0.000e+0
Identity = 266/378 (70.37%), Postives = 321/378 (84.92%), Query Frame = 3 
Query:   69 FLFTSESVGEGHPDKICDQISDAILDAHLKQDPYAKVACESFTKTGMVLVGGEITSHAVVNYSDIVRNTIKRIGFDSSEKGLDYRTCNVLVAIEQQSPDIAQGVYVNRSEDSIGAGDQGLMFGYATDETEECMPMTLILAHKLNQRLAYCRRNDILGWLRPDTKTQVTIAYKNKDGGLLPLYVHTIVISAQHDEEVTLENIKSDLMKHVISNVIDSKMLTSSTIYHLNPSGRFVIGGPQGDAGLTGRKIIVDTYXXXXXXXXXXXXXKDATKVDRSAAYAARWVAKSLVKNGLCKRVLVQFSYAIGIAAPLSIFVYSYNSSTKTDNELLAIVNQNFDLRPGAIIRDLKLREPIFEKTASYGHFGRNEFLWENPKKLHF 1202
            FLFTSESVGEGHPDKICDQISDA+LDAHLKQDP AKVACE+  KTGM+L+ GEITS A V+Y  IVR+TIK IG+D S KG DY+TCNVLVA+EQQSPDIAQGV+++R+E+ +GAGDQGLMFGYATDETEE MP+T++LAHKLN R+A  RRN  L WLRPD+KTQVT+ Y    G ++P+ VHTIV+S QHDE + L+ ++  L + ++  V+ +K L   TIYHL PSGRFVIGGPQGDAGLTGRKIIVDTYGGWGAHGGGAFSGKD TKVDRSAAYAARWVAKSLVK+GLC+RVLVQ +YAIG++ PLSI ++ Y +S K++ ELLAIV +NFDLRPG I+RDL+L++PI+++TA+YGHFGR+ F WE PKKL +
Sbjct:   16 FLFTSESVGEGHPDKICDQISDAVLDAHLKQDPDAKVACETVAKTGMILLAGEITSRASVDYQKIVRDTIKHIGYDDSSKGFDYKTCNVLVALEQQSPDIAQGVHLDRNEEDVGAGDQGLMFGYATDETEEGMPLTIVLAHKLNARMAELRRNGTLPWLRPDSKTQVTVQYMQDRGAVIPIRVHTIVVSVQHDETICLDEMRDALKEKIVKAVVPAKYLDDDTIYHLQPSGRFVIGGPQGDAGLTGRKIIVDTYGGWGAHGGGAFSGKDYTKVDRSAAYAARWVAKSLVKSGLCRRVLVQVAYAIGVSHPLSISIFHYGTSQKSERELLAIVKKNFDLRPGVIVRDLELKKPIYQRTAAYGHFGRDSFPWEVPKKLEY 393
[Close]
BLAST of S-adenosylmethionine synthase vs. Ensembl Xenopus
Match: use1 (unconventional SNARE in the ER 1 homolog [Source:Xenbase;Acc:XB-GENE-972033])

HSP 1 Score: 548.895 bits (1413), Expect = 0.000e+0
Identity = 266/378 (70.37%), Postives = 321/378 (84.92%), Query Frame = 3 
Query:   69 FLFTSESVGEGHPDKICDQISDAILDAHLKQDPYAKVACESFTKTGMVLVGGEITSHAVVNYSDIVRNTIKRIGFDSSEKGLDYRTCNVLVAIEQQSPDIAQGVYVNRSEDSIGAGDQGLMFGYATDETEECMPMTLILAHKLNQRLAYCRRNDILGWLRPDTKTQVTIAYKNKDGGLLPLYVHTIVISAQHDEEVTLENIKSDLMKHVISNVIDSKMLTSSTIYHLNPSGRFVIGGPQGDAGLTGRKIIVDTYXXXXXXXXXXXXXKDATKVDRSAAYAARWVAKSLVKNGLCKRVLVQFSYAIGIAAPLSIFVYSYNSSTKTDNELLAIVNQNFDLRPGAIIRDLKLREPIFEKTASYGHFGRNEFLWENPKKLHF 1202
            FLFTSESVGEGHPDKICDQISDA+LDAHLKQDP AKVACE+  KTGM+L+ GEITS A V+Y  IVR+TIK IG+D S KG DY+TCNVLVA+EQQSPDIAQGV+++R+E+ +GAGDQGLMFGYATDETEE MP+T++LAHKLN R+A  RRN  L WLRPD+KTQVT+ Y    G ++P+ VHTIV+S QHDE + L+ ++  L + ++  V+ +K L   TIYHL PSGRFVIGGPQGDAGLTGRKIIVDTYGGWGAHGGGAFSGKD TKVDRSAAYAARWVAKSLVK+GLC+RVLVQ +YAIG++ PLSI ++ Y +S K++ ELLAIV +NFDLRPG I+RDL+L++PI+++TA+YGHFGR+ F WE PKKL +
Sbjct:   19 FLFTSESVGEGHPDKICDQISDAVLDAHLKQDPDAKVACETVAKTGMILLAGEITSRASVDYQKIVRDTIKHIGYDDSSKGFDYKTCNVLVALEQQSPDIAQGVHLDRNEEDVGAGDQGLMFGYATDETEEGMPLTIVLAHKLNARMAELRRNGTLPWLRPDSKTQVTVQYMQDRGAVIPIRVHTIVVSVQHDETICLDEMRDALKEKIVKAVVPAKYLDDDTIYHLQPSGRFVIGGPQGDAGLTGRKIIVDTYGGWGAHGGGAFSGKDYTKVDRSAAYAARWVAKSLVKSGLCRRVLVQVAYAIGVSHPLSISIFHYGTSQKSERELLAIVKKNFDLRPGVIVRDLELKKPIYQRTAAYGHFGRDSFPWEVPKKLEY 396
[Close]
BLAST of S-adenosylmethionine synthase vs. Ensembl Xenopus
Match: mat1a (methionine adenosyltransferase I, alpha [Source:NCBI gene;Acc:100127858])

HSP 1 Score: 525.013 bits (1351), Expect = 0.000e+0
Identity = 258/363 (71.07%), Postives = 307/363 (84.57%), Query Frame = 3 
Query:  114 ICDQISDAILDAHLKQDPYAKVACESFTKTGMVLVGGEITSHAVVNYSDIVRNTIKRIGFDSSEKGLDYRTCNVLVAIEQQSPDIAQGVYVNRSEDSIGAGDQGLMFGYATDETEECMPMTLILAHKLNQRLAYCRRNDILGWLRPDTKTQVTIAYKNKDGGLLPLYVHTIVISAQHDEEVTLENIKSDLMKHVISNVIDSKMLTSSTIYHLNPSGRFVIGGPQGDAGLTGRKIIVDTYXXXXXXXXXXXXXKDATKVDRSAAYAARWVAKSLVKNGLCKRVLVQFSYAIGIAAPLSIFVYSYNSSTKTDNELLAIVNQNFDLRPGAIIRDLKLREPIFEKTASYGHFGRNEFLWENPKKLHF 1202
            ICDQISDA+LDAHL QDP AKVACE+  KTGMVL+ GEITS AVV+Y  IVR+TIK IG+D SEKG DY+TCNVLVA+EQQSPDIAQGV+++R+E+ IGAGDQGLMFGYATDETEECMP+T++LAHKLN +LA  RRN +L WLRPD+KTQVT+ Y  K+G ++P+ VHTIVIS QHDE ++L +++  L +HVI  V+ +K L   T+YHL PSGRFVIGGPQGDAG+TGRKIIVDTYGGWGAHGGGAFSGKD TKVDRSAAYAARWVAKSLV   LC RVLVQ SYAIG+A PLS+ +++Y +S KT+ ELL IVN NFDLRPG I+RDL L++P+++KTA YGHFGR +F WE PK+L F
Sbjct:    4 ICDQISDAVLDAHLSQDPDAKVACETVCKTGMVLLCGEITSRAVVDYQKIVRDTIKYIGYDDSEKGFDYKTCNVLVALEQQSPDIAQGVHLDRTEEDIGAGDQGLMFGYATDETEECMPLTIVLAHKLNSKLAELRRNGVLPWLRPDSKTQVTVKYIQKNGAVIPVRVHTIVISVQHDETISLSDMQEALKEHVIKAVVPAKYLDEKTVYHLQPSGRFVIGGPQGDAGVTGRKIIVDTYGGWGAHGGGAFSGKDYTKVDRSAAYAARWVAKSLVHAKLCHRVLVQVSYAIGVAYPLSVSLFTYGTSEKTEKELLDIVNANFDLRPGVIVRDLDLKKPLYQKTACYGHFGREDFPWEVPKELFF 366
[Close]
BLAST of S-adenosylmethionine synthase vs. Ensembl Xenopus
Match: use1 (unconventional SNARE in the ER 1 homolog [Source:Xenbase;Acc:XB-GENE-972033])

HSP 1 Score: 520.39 bits (1339), Expect = 0.000e+0
Identity = 253/365 (69.32%), Postives = 308/365 (84.38%), Query Frame = 3 
Query:  108 DKICDQISDAILDAHLKQDPYAKVACESFTKTGMVLVGGEITSHAVVNYSDIVRNTIKRIGFDSSEKGLDYRTCNVLVAIEQQSPDIAQGVYVNRSEDSIGAGDQGLMFGYATDETEECMPMTLILAHKLNQRLAYCRRNDILGWLRPDTKTQVTIAYKNKDGGLLPLYVHTIVISAQHDEEVTLENIKSDLMKHVISNVIDSKMLTSSTIYHLNPSGRFVIGGPQGDAGLTGRKIIVDTYXXXXXXXXXXXXXKDATKVDRSAAYAARWVAKSLVKNGLCKRVLVQFSYAIGIAAPLSIFVYSYNSSTKTDNELLAIVNQNFDLRPGAIIRDLKLREPIFEKTASYGHFGRNEFLWENPKKLHF 1202
            DKICDQISDA+LDAHLKQDP AKVACE+  KTGM+L+ GEITS A V+Y  IVR+TIK IG+D S KG DY+TCNVLVA+EQQSPDIAQGV+++R+E+ +GAGDQGLMFGYATDETEE MP+T++LAHKLN R+A  RRN  L WLRPD+KTQVT+ Y    G ++P+ VHTIV+S QHDE + L+ ++  L + ++  V+ +K L   TIYHL PSGRFVIGGPQGDAGLTGRKIIVDTYGGWGAHGGGAFSGKD TKVDRSAAYAARWVAKSLVK+GLC+RVLVQ +YAIG++ PLSI ++ Y +S K++ ELLAIV +NFDLRPG I+RDL+L++PI+++TA+YGHFGR+ F WE PKKL +
Sbjct:   19 DKICDQISDAVLDAHLKQDPDAKVACETVAKTGMILLAGEITSRASVDYQKIVRDTIKHIGYDDSSKGFDYKTCNVLVALEQQSPDIAQGVHLDRNEEDVGAGDQGLMFGYATDETEEGMPLTIVLAHKLNARMAELRRNGTLPWLRPDSKTQVTVQYMQDRGAVIPIRVHTIVVSVQHDETICLDEMRDALKEKIVKAVVPAKYLDDDTIYHLQPSGRFVIGGPQGDAGLTGRKIIVDTYGGWGAHGGGAFSGKDYTKVDRSAAYAARWVAKSLVKSGLCRRVLVQVAYAIGVSHPLSISIFHYGTSQKSERELLAIVKKNFDLRPGVIVRDLELKKPIYQRTAAYGHFGRDSFPWEVPKKLEY 383
[Close]
BLAST of S-adenosylmethionine synthase vs. Ensembl Mouse
Match: Mat1a (methionine adenosyltransferase I, alpha [Source:MGI Symbol;Acc:MGI:88017])

HSP 1 Score: 555.058 bits (1429), Expect = 0.000e+0
Identity = 270/384 (70.31%), Postives = 327/384 (85.16%), Query Frame = 3 
Query:   51 MDENDIFLFTSESVGEGHPDKICDQISDAILDAHLKQDPYAKVACESFTKTGMVLVGGEITSHAVVNYSDIVRNTIKRIGFDSSEKGLDYRTCNVLVAIEQQSPDIAQGVYVNRSEDSIGAGDQGLMFGYATDETEECMPMTLILAHKLNQRLAYCRRNDILGWLRPDTKTQVTIAYKNKDGGLLPLYVHTIVISAQHDEEVTLENIKSDLMKHVISNVIDSKMLTSSTIYHLNPSGRFVIGGPQGDAGLTGRKIIVDTYXXXXXXXXXXXXXKDATKVDRSAAYAARWVAKSLVKNGLCKRVLVQFSYAIGIAAPLSIFVYSYNSSTKTDNELLAIVNQNFDLRPGAIIRDLKLREPIFEKTASYGHFGRNEFLWENPKKLHF 1202
            + E   F+FTSESVGEGHPDKICDQISDA+LDAHLKQDP AKVACE+  KTGMVL+ GEITS A+V+Y  +VR+TIK IG+D S KG D++TCNVLVA+EQQSPDIAQ V+++R+E+ +GAGDQGLMFGYATDETEECMP+T++LAHKLN R+A  RR+ +L WLRPD+KTQVT+ Y   +G ++P+ +HTIVIS QH+E++TLE ++  L + VI  V+ +K L   T+YHL PSGRFVIGGPQGDAG+TGRKIIVDTYGGWGAHGGGAFSGKD TKVDRSAAYAARWVAKSLVK GLC+RVLVQ SYAIG+A PLSI +++Y +S KT+ ELL +VN+NFDLRPG I+RDL L++PI++KTA YGHFGR+EF WE PKKL F
Sbjct:   13 LSEEGAFMFTSESVGEGHPDKICDQISDAVLDAHLKQDPNAKVACETVCKTGMVLLCGEITSVAMVDYQRVVRDTIKHIGYDDSAKGFDFKTCNVLVALEQQSPDIAQCVHLDRNEEDVGAGDQGLMFGYATDETEECMPLTIVLAHKLNTRIADLRRSGVLPWLRPDSKTQVTVQYMQDNGAVIPVRIHTIVISVQHNEDITLEAMQEALKEQVIKAVVPAKYLDEDTVYHLQPSGRFVIGGPQGDAGVTGRKIIVDTYGGWGAHGGGAFSGKDYTKVDRSAAYAARWVAKSLVKAGLCRRVLVQVSYAIGVAEPLSISIFTYGTSNKTERELLEVVNKNFDLRPGVIVRDLDLKKPIYQKTACYGHFGRSEFPWEVPKKLVF 396
[Close]
BLAST of S-adenosylmethionine synthase vs. Ensembl Mouse
Match: Mat1a (methionine adenosyltransferase I, alpha [Source:MGI Symbol;Acc:MGI:88017])

HSP 1 Score: 555.058 bits (1429), Expect = 0.000e+0
Identity = 270/384 (70.31%), Postives = 327/384 (85.16%), Query Frame = 3 
Query:   51 MDENDIFLFTSESVGEGHPDKICDQISDAILDAHLKQDPYAKVACESFTKTGMVLVGGEITSHAVVNYSDIVRNTIKRIGFDSSEKGLDYRTCNVLVAIEQQSPDIAQGVYVNRSEDSIGAGDQGLMFGYATDETEECMPMTLILAHKLNQRLAYCRRNDILGWLRPDTKTQVTIAYKNKDGGLLPLYVHTIVISAQHDEEVTLENIKSDLMKHVISNVIDSKMLTSSTIYHLNPSGRFVIGGPQGDAGLTGRKIIVDTYXXXXXXXXXXXXXKDATKVDRSAAYAARWVAKSLVKNGLCKRVLVQFSYAIGIAAPLSIFVYSYNSSTKTDNELLAIVNQNFDLRPGAIIRDLKLREPIFEKTASYGHFGRNEFLWENPKKLHF 1202
            + E   F+FTSESVGEGHPDKICDQISDA+LDAHLKQDP AKVACE+  KTGMVL+ GEITS A+V+Y  +VR+TIK IG+D S KG D++TCNVLVA+EQQSPDIAQ V+++R+E+ +GAGDQGLMFGYATDETEECMP+T++LAHKLN R+A  RR+ +L WLRPD+KTQVT+ Y   +G ++P+ +HTIVIS QH+E++TLE ++  L + VI  V+ +K L   T+YHL PSGRFVIGGPQGDAG+TGRKIIVDTYGGWGAHGGGAFSGKD TKVDRSAAYAARWVAKSLVK GLC+RVLVQ SYAIG+A PLSI +++Y +S KT+ ELL +VN+NFDLRPG I+RDL L++PI++KTA YGHFGR+EF WE PKKL F
Sbjct:   13 LSEEGAFMFTSESVGEGHPDKICDQISDAVLDAHLKQDPNAKVACETVCKTGMVLLCGEITSVAMVDYQRVVRDTIKHIGYDDSAKGFDFKTCNVLVALEQQSPDIAQCVHLDRNEEDVGAGDQGLMFGYATDETEECMPLTIVLAHKLNTRIADLRRSGVLPWLRPDSKTQVTVQYMQDNGAVIPVRIHTIVISVQHNEDITLEAMQEALKEQVIKAVVPAKYLDEDTVYHLQPSGRFVIGGPQGDAGVTGRKIIVDTYGGWGAHGGGAFSGKDYTKVDRSAAYAARWVAKSLVKAGLCRRVLVQVSYAIGVAEPLSISIFTYGTSNKTERELLEVVNKNFDLRPGVIVRDLDLKKPIYQKTACYGHFGRSEFPWEVPKKLVF 396
[Close]
BLAST of S-adenosylmethionine synthase vs. Ensembl Mouse
Match: Mat2a (methionine adenosyltransferase II, alpha [Source:MGI Symbol;Acc:MGI:2443731])

HSP 1 Score: 553.903 bits (1426), Expect = 0.000e+0
Identity = 271/382 (70.94%), Postives = 319/382 (83.51%), Query Frame = 3 
Query:   57 ENDIFLFTSESVGEGHPDKICDQISDAILDAHLKQDPYAKVACESFTKTGMVLVGGEITSHAVVNYSDIVRNTIKRIGFDSSEKGLDYRTCNVLVAIEQQSPDIAQGVYVNRSEDSIGAGDQGLMFGYATDETEECMPMTLILAHKLNQRLAYCRRNDILGWLRPDTKTQVTIAYKNKDGGLLPLYVHTIVISAQHDEEVTLENIKSDLMKHVISNVIDSKMLTSSTIYHLNPSGRFVIGGPQGDAGLTGRKIIVDTYXXXXXXXXXXXXXKDATKVDRSAAYAARWVAKSLVKNGLCKRVLVQFSYAIGIAAPLSIFVYSYNSSTKTDNELLAIVNQNFDLRPGAIIRDLKLREPIFEKTASYGHFGRNEFLWENPKKLHF 1202
            E   FLFTSESVGEGHPDKICDQISDA+LDAHL+QDP AKVACE+  KTGM+L+ GEITS A ++Y  +VR  IK IG+D S KG DY+TCNVLVA+EQQSPDIAQGV+++R+E+ IGAGDQGLMFGYATDETEECMP+T++LAHKLN +LA  RRN  L WLRPD+KTQVT+ Y    G +LP+ VHTIVIS QHDEEV L+ ++  L + VI  V+ +K L   TIYHL PSGRFVIGGPQGDAGLTGRKIIVDTYGGWGAHGGGAFSGKD TKVDRSAAYAARWVAKSLVK GLC+RVLVQ SYAIG++ PLSI ++ Y +S K++ ELL IV +NFDLRPG I+RDL L++PI+++TA+YGHFGR+ F WE PKKL +
Sbjct:   14 EEGTFLFTSESVGEGHPDKICDQISDAVLDAHLQQDPDAKVACETVAKTGMILLAGEITSRAAIDYQKVVREAIKHIGYDDSSKGFDYKTCNVLVALEQQSPDIAQGVHLDRNEEDIGAGDQGLMFGYATDETEECMPLTIVLAHKLNAKLAELRRNGTLPWLRPDSKTQVTVQYMQDRGAVLPIRVHTIVISVQHDEEVCLDEMRDALKEKVIKAVVPAKYLDEDTIYHLQPSGRFVIGGPQGDAGLTGRKIIVDTYGGWGAHGGGAFSGKDYTKVDRSAAYAARWVAKSLVKGGLCRRVLVQVSYAIGVSHPLSISIFHYGTSQKSERELLEIVKKNFDLRPGVIVRDLDLKKPIYQRTAAYGHFGRDSFPWEVPKKLKY 395
[Close]
BLAST of S-adenosylmethionine synthase vs. Ensembl Mouse
Match: Mat2a (methionine adenosyltransferase II, alpha [Source:MGI Symbol;Acc:MGI:2443731])

HSP 1 Score: 553.903 bits (1426), Expect = 0.000e+0
Identity = 271/382 (70.94%), Postives = 319/382 (83.51%), Query Frame = 3 
Query:   57 ENDIFLFTSESVGEGHPDKICDQISDAILDAHLKQDPYAKVACESFTKTGMVLVGGEITSHAVVNYSDIVRNTIKRIGFDSSEKGLDYRTCNVLVAIEQQSPDIAQGVYVNRSEDSIGAGDQGLMFGYATDETEECMPMTLILAHKLNQRLAYCRRNDILGWLRPDTKTQVTIAYKNKDGGLLPLYVHTIVISAQHDEEVTLENIKSDLMKHVISNVIDSKMLTSSTIYHLNPSGRFVIGGPQGDAGLTGRKIIVDTYXXXXXXXXXXXXXKDATKVDRSAAYAARWVAKSLVKNGLCKRVLVQFSYAIGIAAPLSIFVYSYNSSTKTDNELLAIVNQNFDLRPGAIIRDLKLREPIFEKTASYGHFGRNEFLWENPKKLHF 1202
            E   FLFTSESVGEGHPDKICDQISDA+LDAHL+QDP AKVACE+  KTGM+L+ GEITS A ++Y  +VR  IK IG+D S KG DY+TCNVLVA+EQQSPDIAQGV+++R+E+ IGAGDQGLMFGYATDETEECMP+T++LAHKLN +LA  RRN  L WLRPD+KTQVT+ Y    G +LP+ VHTIVIS QHDEEV L+ ++  L + VI  V+ +K L   TIYHL PSGRFVIGGPQGDAGLTGRKIIVDTYGGWGAHGGGAFSGKD TKVDRSAAYAARWVAKSLVK GLC+RVLVQ SYAIG++ PLSI ++ Y +S K++ ELL IV +NFDLRPG I+RDL L++PI+++TA+YGHFGR+ F WE PKKL +
Sbjct:   14 EEGTFLFTSESVGEGHPDKICDQISDAVLDAHLQQDPDAKVACETVAKTGMILLAGEITSRAAIDYQKVVREAIKHIGYDDSSKGFDYKTCNVLVALEQQSPDIAQGVHLDRNEEDIGAGDQGLMFGYATDETEECMPLTIVLAHKLNAKLAELRRNGTLPWLRPDSKTQVTVQYMQDRGAVLPIRVHTIVISVQHDEEVCLDEMRDALKEKVIKAVVPAKYLDEDTIYHLQPSGRFVIGGPQGDAGLTGRKIIVDTYGGWGAHGGGAFSGKDYTKVDRSAAYAARWVAKSLVKGGLCRRVLVQVSYAIGVSHPLSISIFHYGTSQKSERELLEIVKKNFDLRPGVIVRDLDLKKPIYQRTAAYGHFGRDSFPWEVPKKLKY 395
[Close]
BLAST of S-adenosylmethionine synthase vs. Ensembl Mouse
Match: Mat2a (methionine adenosyltransferase II, alpha [Source:MGI Symbol;Acc:MGI:2443731])

HSP 1 Score: 505.753 bits (1301), Expect = 1.338e-179
Identity = 251/349 (71.92%), Postives = 291/349 (83.38%), Query Frame = 3 
Query:   57 ENDIFLFTSESVGEGHPDKICDQISDAILDAHLKQDPYAKVACESFTKTGMVLVGGEITSHAVVNYSDIVRNTIKRIGFDSSEKGLDYRTCNVLVAIEQQSPDIAQGVYVNRSEDSIGAGDQGLMFGYATDETEECMPMTLILAHKLNQRLAYCRRNDILGWLRPDTKTQVTIAYKNKDGGLLPLYVHTIVISAQHDEEVTLENIKSDLMKHVISNVIDSKMLTSSTIYHLNPSGRFVIGGPQGDAGLTGRKIIVDTYXXXXXXXXXXXXXKDATKVDRSAAYAARWVAKSLVKNGLCKRVLVQFSYAIGIAAPLSIFVYSYNSSTKTDNELLAIVNQNFDLRPGAIIR 1103
            E   FLFTSESVGEGHPDKICDQISDA+LDAHL+QDP AKVACE+  KTGM+L+ GEITS A ++Y  +VR  IK IG+D S KG DY+TCNVLVA+EQQSPDIAQGV+++R+E+ IGAGDQGLMFGYATDETEECMP+T++LAHKLN +LA  RRN  L WLRPD+KTQVT+ Y    G +LP+ VHTIVIS QHDEEV L+ ++  L + VI  V+ +K L   TIYHL PSGRFVIGGPQGDAGLTGRKIIVDTYGGWGAHGGGAFSGKD TKVDRSAAYAARWVAKSLVK GLC+RVLVQ SYAIG++ PLSI ++ Y +S K++ ELL IV +NFDLRPG I+R
Sbjct:   14 EEGTFLFTSESVGEGHPDKICDQISDAVLDAHLQQDPDAKVACETVAKTGMILLAGEITSRAAIDYQKVVREAIKHIGYDDSSKGFDYKTCNVLVALEQQSPDIAQGVHLDRNEEDIGAGDQGLMFGYATDETEECMPLTIVLAHKLNAKLAELRRNGTLPWLRPDSKTQVTVQYMQDRGAVLPIRVHTIVISVQHDEEVCLDEMRDALKEKVIKAVVPAKYLDEDTIYHLQPSGRFVIGGPQGDAGLTGRKIIVDTYGGWGAHGGGAFSGKDYTKVDRSAAYAARWVAKSLVKGGLCRRVLVQVSYAIGVSHPLSISIFHYGTSQKSERELLEIVKKNFDLRPGVIVR 362
[Close]
BLAST of S-adenosylmethionine synthase vs. UniProt/SwissProt
Match: sp|Q91X83|METK1_MOUSE (S-adenosylmethionine synthase isoform type-1 OS=Mus musculus OX=10090 GN=Mat1a PE=1 SV=1)

HSP 1 Score: 555.058 bits (1429), Expect = 0.000e+0
Identity = 270/384 (70.31%), Postives = 327/384 (85.16%), Query Frame = 3 
Query:   51 MDENDIFLFTSESVGEGHPDKICDQISDAILDAHLKQDPYAKVACESFTKTGMVLVGGEITSHAVVNYSDIVRNTIKRIGFDSSEKGLDYRTCNVLVAIEQQSPDIAQGVYVNRSEDSIGAGDQGLMFGYATDETEECMPMTLILAHKLNQRLAYCRRNDILGWLRPDTKTQVTIAYKNKDGGLLPLYVHTIVISAQHDEEVTLENIKSDLMKHVISNVIDSKMLTSSTIYHLNPSGRFVIGGPQGDAGLTGRKIIVDTYXXXXXXXXXXXXXKDATKVDRSAAYAARWVAKSLVKNGLCKRVLVQFSYAIGIAAPLSIFVYSYNSSTKTDNELLAIVNQNFDLRPGAIIRDLKLREPIFEKTASYGHFGRNEFLWENPKKLHF 1202
            + E   F+FTSESVGEGHPDKICDQISDA+LDAHLKQDP AKVACE+  KTGMVL+ GEITS A+V+Y  +VR+TIK IG+D S KG D++TCNVLVA+EQQSPDIAQ V+++R+E+ +GAGDQGLMFGYATDETEECMP+T++LAHKLN R+A  RR+ +L WLRPD+KTQVT+ Y   +G ++P+ +HTIVIS QH+E++TLE ++  L + VI  V+ +K L   T+YHL PSGRFVIGGPQGDAG+TGRKIIVDTYGGWGAHGGGAFSGKD TKVDRSAAYAARWVAKSLVK GLC+RVLVQ SYAIG+A PLSI +++Y +S KT+ ELL +VN+NFDLRPG I+RDL L++PI++KTA YGHFGR+EF WE PKKL F
Sbjct:   13 LSEEGAFMFTSESVGEGHPDKICDQISDAVLDAHLKQDPNAKVACETVCKTGMVLLCGEITSVAMVDYQRVVRDTIKHIGYDDSAKGFDFKTCNVLVALEQQSPDIAQCVHLDRNEEDVGAGDQGLMFGYATDETEECMPLTIVLAHKLNTRIADLRRSGVLPWLRPDSKTQVTVQYMQDNGAVIPVRIHTIVISVQHNEDITLEAMQEALKEQVIKAVVPAKYLDEDTVYHLQPSGRFVIGGPQGDAGVTGRKIIVDTYGGWGAHGGGAFSGKDYTKVDRSAAYAARWVAKSLVKAGLCRRVLVQVSYAIGVAEPLSISIFTYGTSNKTERELLEVVNKNFDLRPGVIVRDLDLKKPIYQKTACYGHFGRSEFPWEVPKKLVF 396
[Close]
BLAST of S-adenosylmethionine synthase vs. UniProt/SwissProt
Match: sp|Q5R5H1|METK2_PONAB (S-adenosylmethionine synthase isoform type-2 OS=Pongo abelii OX=9601 GN=MAT2A PE=2 SV=1)

HSP 1 Score: 554.288 bits (1427), Expect = 0.000e+0
Identity = 271/382 (70.94%), Postives = 319/382 (83.51%), Query Frame = 3 
Query:   57 ENDIFLFTSESVGEGHPDKICDQISDAILDAHLKQDPYAKVACESFTKTGMVLVGGEITSHAVVNYSDIVRNTIKRIGFDSSEKGLDYRTCNVLVAIEQQSPDIAQGVYVNRSEDSIGAGDQGLMFGYATDETEECMPMTLILAHKLNQRLAYCRRNDILGWLRPDTKTQVTIAYKNKDGGLLPLYVHTIVISAQHDEEVTLENIKSDLMKHVISNVIDSKMLTSSTIYHLNPSGRFVIGGPQGDAGLTGRKIIVDTYXXXXXXXXXXXXXKDATKVDRSAAYAARWVAKSLVKNGLCKRVLVQFSYAIGIAAPLSIFVYSYNSSTKTDNELLAIVNQNFDLRPGAIIRDLKLREPIFEKTASYGHFGRNEFLWENPKKLHF 1202
            E   FLFTSESVGEGHPDKICDQISDA+LDAHL+QDP AKVACE+  KTGM+L+ GEITS A V+Y  +VR  +K IG+D S KG DY+TCNVLVA+EQQSPDIAQGV+++R+E+ IGAGDQGLMFGYATDETEECMP+T++LAHKLN +LA  RRN  L WLRPD+KTQVT+ Y    G +LP+ VHTIVIS QHDEEV L+ ++  L + VI  V+ +K L   TIYHL PSGRFVIGGPQGDAGLTGRKIIVDTYGGWGAHGGGAFSGKD TKVDRSAAYAARWVAKSLVK GLC+RVLVQ SYAIG++ PLSI ++ Y +S K++ ELL IV +NFDLRPG I+RDL L++PI+++TA+YGHFGR+ F WE PKKL +
Sbjct:   14 EEGTFLFTSESVGEGHPDKICDQISDAVLDAHLQQDPDAKVACETVAKTGMILLAGEITSRAAVDYQKVVREAVKHIGYDDSSKGFDYKTCNVLVALEQQSPDIAQGVHLDRNEEDIGAGDQGLMFGYATDETEECMPLTIVLAHKLNAKLAELRRNGTLPWLRPDSKTQVTVQYMQDRGAVLPIRVHTIVISVQHDEEVCLDEMRDALKEKVIKAVVPAKYLDEDTIYHLQPSGRFVIGGPQGDAGLTGRKIIVDTYGGWGAHGGGAFSGKDYTKVDRSAAYAARWVAKSLVKGGLCRRVLVQVSYAIGVSHPLSISIFHYGTSQKSERELLEIVKKNFDLRPGVIVRDLDLKKPIYQRTAAYGHFGRDSFPWEVPKKLKY 395
[Close]
BLAST of S-adenosylmethionine synthase vs. UniProt/SwissProt
Match: sp|Q4R924|METK2_MACFA (S-adenosylmethionine synthase isoform type-2 OS=Macaca fascicularis OX=9541 GN=MAT2A PE=2 SV=1)

HSP 1 Score: 554.288 bits (1427), Expect = 0.000e+0
Identity = 271/382 (70.94%), Postives = 319/382 (83.51%), Query Frame = 3 
Query:   57 ENDIFLFTSESVGEGHPDKICDQISDAILDAHLKQDPYAKVACESFTKTGMVLVGGEITSHAVVNYSDIVRNTIKRIGFDSSEKGLDYRTCNVLVAIEQQSPDIAQGVYVNRSEDSIGAGDQGLMFGYATDETEECMPMTLILAHKLNQRLAYCRRNDILGWLRPDTKTQVTIAYKNKDGGLLPLYVHTIVISAQHDEEVTLENIKSDLMKHVISNVIDSKMLTSSTIYHLNPSGRFVIGGPQGDAGLTGRKIIVDTYXXXXXXXXXXXXXKDATKVDRSAAYAARWVAKSLVKNGLCKRVLVQFSYAIGIAAPLSIFVYSYNSSTKTDNELLAIVNQNFDLRPGAIIRDLKLREPIFEKTASYGHFGRNEFLWENPKKLHF 1202
            E   FLFTSESVGEGHPDKICDQISDA+LDAHL+QDP AKVACE+  KTGM+L+ GEITS A V+Y  +VR  +K IG+D S KG DY+TCNVLVA+EQQSPDIAQGV+++R+E+ IGAGDQGLMFGYATDETEECMP+T++LAHKLN +LA  RRN  L WLRPD+KTQVT+ Y    G +LP+ VHTIVIS QHDEEV L+ ++  L + VI  V+ +K L   TIYHL PSGRFVIGGPQGDAGLTGRKIIVDTYGGWGAHGGGAFSGKD TKVDRSAAYAARWVAKSLVK GLC+RVLVQ SYAIG++ PLSI ++ Y +S K++ ELL IV +NFDLRPG I+RDL L++PI+++TA+YGHFGR+ F WE PKKL +
Sbjct:   14 EEGTFLFTSESVGEGHPDKICDQISDAVLDAHLQQDPDAKVACETVAKTGMILLAGEITSRAAVDYQKVVREAVKHIGYDDSSKGFDYKTCNVLVALEQQSPDIAQGVHLDRNEEDIGAGDQGLMFGYATDETEECMPLTIVLAHKLNAKLAELRRNGTLPWLRPDSKTQVTVQYMQDRGAVLPIRVHTIVISVQHDEEVCLDEMRDALKEKVIKAVVPAKYLDEDTIYHLQPSGRFVIGGPQGDAGLTGRKIIVDTYGGWGAHGGGAFSGKDYTKVDRSAAYAARWVAKSLVKGGLCRRVLVQVSYAIGVSHPLSISIFHYGTSQKSERELLEIVKKNFDLRPGVIVRDLDLKKPIYQRTAAYGHFGRDSFPWEVPKKLKY 395
[Close]
BLAST of S-adenosylmethionine synthase vs. UniProt/SwissProt
Match: sp|P31153|METK2_HUMAN (S-adenosylmethionine synthase isoform type-2 OS=Homo sapiens OX=9606 GN=MAT2A PE=1 SV=1)

HSP 1 Score: 554.288 bits (1427), Expect = 0.000e+0
Identity = 271/382 (70.94%), Postives = 319/382 (83.51%), Query Frame = 3 
Query:   57 ENDIFLFTSESVGEGHPDKICDQISDAILDAHLKQDPYAKVACESFTKTGMVLVGGEITSHAVVNYSDIVRNTIKRIGFDSSEKGLDYRTCNVLVAIEQQSPDIAQGVYVNRSEDSIGAGDQGLMFGYATDETEECMPMTLILAHKLNQRLAYCRRNDILGWLRPDTKTQVTIAYKNKDGGLLPLYVHTIVISAQHDEEVTLENIKSDLMKHVISNVIDSKMLTSSTIYHLNPSGRFVIGGPQGDAGLTGRKIIVDTYXXXXXXXXXXXXXKDATKVDRSAAYAARWVAKSLVKNGLCKRVLVQFSYAIGIAAPLSIFVYSYNSSTKTDNELLAIVNQNFDLRPGAIIRDLKLREPIFEKTASYGHFGRNEFLWENPKKLHF 1202
            E   FLFTSESVGEGHPDKICDQISDA+LDAHL+QDP AKVACE+  KTGM+L+ GEITS A V+Y  +VR  +K IG+D S KG DY+TCNVLVA+EQQSPDIAQGV+++R+E+ IGAGDQGLMFGYATDETEECMP+T++LAHKLN +LA  RRN  L WLRPD+KTQVT+ Y    G +LP+ VHTIVIS QHDEEV L+ ++  L + VI  V+ +K L   TIYHL PSGRFVIGGPQGDAGLTGRKIIVDTYGGWGAHGGGAFSGKD TKVDRSAAYAARWVAKSLVK GLC+RVLVQ SYAIG++ PLSI ++ Y +S K++ ELL IV +NFDLRPG I+RDL L++PI+++TA+YGHFGR+ F WE PKKL +
Sbjct:   14 EEGTFLFTSESVGEGHPDKICDQISDAVLDAHLQQDPDAKVACETVAKTGMILLAGEITSRAAVDYQKVVREAVKHIGYDDSSKGFDYKTCNVLVALEQQSPDIAQGVHLDRNEEDIGAGDQGLMFGYATDETEECMPLTIVLAHKLNAKLAELRRNGTLPWLRPDSKTQVTVQYMQDRGAVLPIRVHTIVISVQHDEEVCLDEMRDALKEKVIKAVVPAKYLDEDTIYHLQPSGRFVIGGPQGDAGLTGRKIIVDTYGGWGAHGGGAFSGKDYTKVDRSAAYAARWVAKSLVKGGLCRRVLVQVSYAIGVSHPLSISIFHYGTSQKSERELLEIVKKNFDLRPGVIVRDLDLKKPIYQRTAAYGHFGRDSFPWEVPKKLKY 395
[Close]
BLAST of S-adenosylmethionine synthase vs. UniProt/SwissProt
Match: sp|Q3THS6|METK2_MOUSE (S-adenosylmethionine synthase isoform type-2 OS=Mus musculus OX=10090 GN=Mat2a PE=1 SV=2)

HSP 1 Score: 553.903 bits (1426), Expect = 0.000e+0
Identity = 271/382 (70.94%), Postives = 319/382 (83.51%), Query Frame = 3 
Query:   57 ENDIFLFTSESVGEGHPDKICDQISDAILDAHLKQDPYAKVACESFTKTGMVLVGGEITSHAVVNYSDIVRNTIKRIGFDSSEKGLDYRTCNVLVAIEQQSPDIAQGVYVNRSEDSIGAGDQGLMFGYATDETEECMPMTLILAHKLNQRLAYCRRNDILGWLRPDTKTQVTIAYKNKDGGLLPLYVHTIVISAQHDEEVTLENIKSDLMKHVISNVIDSKMLTSSTIYHLNPSGRFVIGGPQGDAGLTGRKIIVDTYXXXXXXXXXXXXXKDATKVDRSAAYAARWVAKSLVKNGLCKRVLVQFSYAIGIAAPLSIFVYSYNSSTKTDNELLAIVNQNFDLRPGAIIRDLKLREPIFEKTASYGHFGRNEFLWENPKKLHF 1202
            E   FLFTSESVGEGHPDKICDQISDA+LDAHL+QDP AKVACE+  KTGM+L+ GEITS A ++Y  +VR  IK IG+D S KG DY+TCNVLVA+EQQSPDIAQGV+++R+E+ IGAGDQGLMFGYATDETEECMP+T++LAHKLN +LA  RRN  L WLRPD+KTQVT+ Y    G +LP+ VHTIVIS QHDEEV L+ ++  L + VI  V+ +K L   TIYHL PSGRFVIGGPQGDAGLTGRKIIVDTYGGWGAHGGGAFSGKD TKVDRSAAYAARWVAKSLVK GLC+RVLVQ SYAIG++ PLSI ++ Y +S K++ ELL IV +NFDLRPG I+RDL L++PI+++TA+YGHFGR+ F WE PKKL +
Sbjct:   14 EEGTFLFTSESVGEGHPDKICDQISDAVLDAHLQQDPDAKVACETVAKTGMILLAGEITSRAAIDYQKVVREAIKHIGYDDSSKGFDYKTCNVLVALEQQSPDIAQGVHLDRNEEDIGAGDQGLMFGYATDETEECMPLTIVLAHKLNAKLAELRRNGTLPWLRPDSKTQVTVQYMQDRGAVLPIRVHTIVISVQHDEEVCLDEMRDALKEKVIKAVVPAKYLDEDTIYHLQPSGRFVIGGPQGDAGLTGRKIIVDTYGGWGAHGGGAFSGKDYTKVDRSAAYAARWVAKSLVKGGLCRRVLVQVSYAIGVSHPLSISIFHYGTSQKSERELLEIVKKNFDLRPGVIVRDLDLKKPIYQRTAAYGHFGRDSFPWEVPKKLKY 395
[Close]
BLAST of S-adenosylmethionine synthase vs. TrEMBL
Match: A0A1I8HKQ4 (S-adenosylmethionine synthase OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig008771g1 PE=3 SV=1)

HSP 1 Score: 571.622 bits (1472), Expect = 0.000e+0
Identity = 276/378 (73.02%), Postives = 325/378 (85.98%), Query Frame = 3 
Query:   69 FLFTSESVGEGHPDKICDQISDAILDAHLKQDPYAKVACESFTKTGMVLVGGEITSHAVVNYSDIVRNTIKRIGFDSSEKGLDYRTCNVLVAIEQQSPDIAQGVYVNRSEDSIGAGDQGLMFGYATDETEECMPMTLILAHKLNQRLAYCRRNDILGWLRPDTKTQVTIAYKNKDGGLLPLYVHTIVISAQHDEEVTLENIKSDLMKHVISNVIDSKMLTSSTIYHLNPSGRFVIGGPQGDAGLTGRKIIVDTYXXXXXXXXXXXXXKDATKVDRSAAYAARWVAKSLVKNGLCKRVLVQFSYAIGIAAPLSIFVYSYNSSTKTDNELLAIVNQNFDLRPGAIIRDLKLREPIFEKTASYGHFGRNEFLWENPKKLHF 1202
            FLFTSESVGEGHPDKICDQ+SDA+LDAHLKQDP AKVACE FTKTGM+LVGGEITS AVV+Y  ++R TIK IG+D S KG DY+TCNVLVA+E+QSPDIAQGV+  RSED IGAGDQGLMFGYATDET ECMP+T++LAHKLN +LA CRR+  L WLRPDTKTQVT+ YK+++G  +PL +HTIV+S QHDE VT E ++ D+M+HV+  V  S ML  +TIYHLNPSGRFVIGGPQ DAGLTGRKIIVDTYGGWGAHGGGAFSGKD +KVDRSAAYAARWVAKSLVK+GLC+RVLVQ SYAIG++ PL++++ SY +  ++D ELL IV +NFDLRPG I+RDL+LR+PI++KT+ YGHFGR+EF WE  K L F
Sbjct:   10 FLFTSESVGEGHPDKICDQVSDAVLDAHLKQDPNAKVACECFTKTGMILVGGEITSKAVVDYQRVIRGTIKDIGYDDSNKGFDYKTCNVLVALEEQSPDIAQGVHEARSEDDIGAGDQGLMFGYATDETVECMPLTIVLAHKLNAQLAQCRRDGTLPWLRPDTKTQVTVEYKDENGACVPLRIHTIVVSTQHDESVTQEQLRKDVMEHVVKAVCPSDMLDENTIYHLNPSGRFVIGGPQSDAGLTGRKIIVDTYGGWGAHGGGAFSGKDFSKVDRSAAYAARWVAKSLVKSGLCRRVLVQVSYAIGVSKPLAVYLNSYGTGKRSDEELLHIVEENFDLRPGCIVRDLELRKPIYQKTSCYGHFGRDEFTWEQAKPLKF 387
[Close]
BLAST of S-adenosylmethionine synthase vs. TrEMBL
Match: A0A1I8I605 (S-adenosylmethionine synthase OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig008771g3 PE=3 SV=1)

HSP 1 Score: 571.237 bits (1471), Expect = 0.000e+0
Identity = 276/378 (73.02%), Postives = 325/378 (85.98%), Query Frame = 3 
Query:   69 FLFTSESVGEGHPDKICDQISDAILDAHLKQDPYAKVACESFTKTGMVLVGGEITSHAVVNYSDIVRNTIKRIGFDSSEKGLDYRTCNVLVAIEQQSPDIAQGVYVNRSEDSIGAGDQGLMFGYATDETEECMPMTLILAHKLNQRLAYCRRNDILGWLRPDTKTQVTIAYKNKDGGLLPLYVHTIVISAQHDEEVTLENIKSDLMKHVISNVIDSKMLTSSTIYHLNPSGRFVIGGPQGDAGLTGRKIIVDTYXXXXXXXXXXXXXKDATKVDRSAAYAARWVAKSLVKNGLCKRVLVQFSYAIGIAAPLSIFVYSYNSSTKTDNELLAIVNQNFDLRPGAIIRDLKLREPIFEKTASYGHFGRNEFLWENPKKLHF 1202
            FLFTSESVGEGHPDKICDQ+SDA+LDAHLKQDP AKVACE FTKTGM+LVGGEITS AVV+Y  ++R TIK IG+D S KG DY+TCNVLVA+E+QSPDIAQGV+  RSED IGAGDQGLMFGYATDET ECMP+T++LAHKLN +LA CRR+  L WLRPDTKTQVT+ YK+++G  +PL +HTIV+S QHDE VT E ++ D+M+HV+  V  S ML  +TIYHLNPSGRFVIGGPQ DAGLTGRKIIVDTYGGWGAHGGGAFSGKD +KVDRSAAYAARWVAKSLVK+GLC+RVLVQ SYAIG++ PL++++ SY +  ++D ELL IV +NFDLRPG I+RDL+LR+PI++KT+ YGHFGR+EF WE  K L F
Sbjct:   10 FLFTSESVGEGHPDKICDQVSDAVLDAHLKQDPNAKVACECFTKTGMILVGGEITSKAVVDYQRVIRGTIKDIGYDDSNKGFDYKTCNVLVALEEQSPDIAQGVHEARSEDDIGAGDQGLMFGYATDETVECMPLTIVLAHKLNAQLAQCRRDGTLPWLRPDTKTQVTVEYKDENGACVPLRIHTIVVSTQHDESVTQEQLRKDVMEHVVKAVCPSDMLDENTIYHLNPSGRFVIGGPQSDAGLTGRKIIVDTYGGWGAHGGGAFSGKDFSKVDRSAAYAARWVAKSLVKSGLCRRVLVQVSYAIGVSKPLAVYLNSYGTGKRSDEELLRIVEENFDLRPGCIVRDLELRKPIYQKTSCYGHFGRDEFTWEQAKPLKF 387
[Close]
BLAST of S-adenosylmethionine synthase vs. TrEMBL
Match: A0A267DP28 (S-adenosylmethionine synthase OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig008771g2 PE=3 SV=1)

HSP 1 Score: 570.852 bits (1470), Expect = 0.000e+0
Identity = 276/378 (73.02%), Postives = 324/378 (85.71%), Query Frame = 3 
Query:   69 FLFTSESVGEGHPDKICDQISDAILDAHLKQDPYAKVACESFTKTGMVLVGGEITSHAVVNYSDIVRNTIKRIGFDSSEKGLDYRTCNVLVAIEQQSPDIAQGVYVNRSEDSIGAGDQGLMFGYATDETEECMPMTLILAHKLNQRLAYCRRNDILGWLRPDTKTQVTIAYKNKDGGLLPLYVHTIVISAQHDEEVTLENIKSDLMKHVISNVIDSKMLTSSTIYHLNPSGRFVIGGPQGDAGLTGRKIIVDTYXXXXXXXXXXXXXKDATKVDRSAAYAARWVAKSLVKNGLCKRVLVQFSYAIGIAAPLSIFVYSYNSSTKTDNELLAIVNQNFDLRPGAIIRDLKLREPIFEKTASYGHFGRNEFLWENPKKLHF 1202
            FLFTSESVGEGHPDKICDQ+SDA+LDAHLKQDP AKVACE FTKTGM+LVGGEITS AVV+Y  ++R TIK IG+D S KG DY+TCNVLVA+E+QSPDIAQGV+  RSED IGAGDQGLMFGYATDET ECMP+T++LAHKLN +LA CRR+  L WLRPDTKTQVT+ YK+++G  +PL +HTIV+S QHDE VT E ++ D+M HV+  V  S ML  +TIYHLNPSGRFVIGGPQ DAGLTGRKIIVDTYGGWGAHGGGAFSGKD +KVDRSAAYAARWVAKSLVK+GLC+RVLVQ SYAIG++ PL++++ SY +  ++D ELL IV +NFDLRPG I+RDL+LR+PI++KT+ YGHFGR+EF WE  K L F
Sbjct:   10 FLFTSESVGEGHPDKICDQVSDAVLDAHLKQDPNAKVACECFTKTGMILVGGEITSKAVVDYQRVIRGTIKDIGYDDSNKGFDYKTCNVLVALEEQSPDIAQGVHEARSEDDIGAGDQGLMFGYATDETVECMPLTIVLAHKLNAQLAQCRRDGTLPWLRPDTKTQVTVEYKDENGACVPLRIHTIVVSTQHDESVTQEQLRKDVMDHVVKAVCPSDMLDENTIYHLNPSGRFVIGGPQSDAGLTGRKIIVDTYGGWGAHGGGAFSGKDFSKVDRSAAYAARWVAKSLVKSGLCRRVLVQVSYAIGVSKPLAVYLNSYGTGKRSDEELLRIVEENFDLRPGCIVRDLELRKPIYQKTSCYGHFGRDEFTWEQAKPLKF 387
[Close]
BLAST of S-adenosylmethionine synthase vs. TrEMBL
Match: H9G9N0 (S-adenosylmethionine synthase OS=Anolis carolinensis OX=28377 GN=MAT1A PE=3 SV=2)

HSP 1 Score: 566.614 bits (1459), Expect = 0.000e+0
Identity = 277/383 (72.32%), Postives = 329/383 (85.90%), Query Frame = 3 
Query:   54 DENDIFLFTSESVGEGHPDKICDQISDAILDAHLKQDPYAKVACESFTKTGMVLVGGEITSHAVVNYSDIVRNTIKRIGFDSSEKGLDYRTCNVLVAIEQQSPDIAQGVYVNRSEDSIGAGDQGLMFGYATDETEECMPMTLILAHKLNQRLAYCRRNDILGWLRPDTKTQVTIAYKNKDGGLLPLYVHTIVISAQHDEEVTLENIKSDLMKHVISNVIDSKMLTSSTIYHLNPSGRFVIGGPQGDAGLTGRKIIVDTYXXXXXXXXXXXXXKDATKVDRSAAYAARWVAKSLVKNGLCKRVLVQFSYAIGIAAPLSIFVYSYNSSTKTDNELLAIVNQNFDLRPGAIIRDLKLREPIFEKTASYGHFGRNEFLWENPKKLHF 1202
            +E   F+FTSESVGEGHPDKICDQISDA+LDAHLKQDP AKVACE+  KTGMVL+ GEITS AVV+Y  IVR+TI  IG+D S KG DY+TCNVLVA+EQQSPDIAQGV+++RSE+ +GAGDQGLMFGYATDETEECMP+T++LAHKLN ++A  RRN IL WLRPD+KTQ+T+ Y  KDG  +PL VHTIVISAQHDE ++L+ ++  L +HVI  V+  + L   T+YHL PSGRFVIGGPQGDAG+TGRKIIVDTYGGWGAHGGGAFSGKD TKVDRSAAYAARWVAKSLVK GLC+RVLVQ +YAIG+A PLS+ +++Y +ST+T+ ELL IV+QNFDLRPGAI++DL L++PI++KTA YGHFGR+EF WE PKKL F
Sbjct:   15 EEAGAFMFTSESVGEGHPDKICDQISDAVLDAHLKQDPNAKVACETVCKTGMVLLCGEITSTAVVDYQQIVRDTIMNIGYDDSSKGFDYKTCNVLVALEQQSPDIAQGVHLHRSEEEVGAGDQGLMFGYATDETEECMPLTIMLAHKLNAKMAELRRNGILPWLRPDSKTQITVQYVKKDGVAIPLRVHTIVISAQHDETISLDAMRKALREHVIKAVVPPRYLDDKTVYHLQPSGRFVIGGPQGDAGVTGRKIIVDTYGGWGAHGGGAFSGKDYTKVDRSAAYAARWVAKSLVKAGLCRRVLVQVAYAIGVAEPLSVSLFTYGTSTRTEQELLNIVHQNFDLRPGAIVKDLDLKKPIYQKTACYGHFGRSEFSWEVPKKLAF 397
[Close]
BLAST of S-adenosylmethionine synthase vs. TrEMBL
Match: A0A1A7Z0I6 (S-adenosylmethionine synthase OS=Iconisemion striatum OX=60296 GN=MAT2AB PE=3 SV=1)

HSP 1 Score: 566.229 bits (1458), Expect = 0.000e+0
Identity = 277/382 (72.51%), Postives = 325/382 (85.08%), Query Frame = 3 
Query:   57 ENDIFLFTSESVGEGHPDKICDQISDAILDAHLKQDPYAKVACESFTKTGMVLVGGEITSHAVVNYSDIVRNTIKRIGFDSSEKGLDYRTCNVLVAIEQQSPDIAQGVYVNRSEDSIGAGDQGLMFGYATDETEECMPMTLILAHKLNQRLAYCRRNDILGWLRPDTKTQVTIAYKNKDGGLLPLYVHTIVISAQHDEEVTLENIKSDLMKHVISNVIDSKMLTSSTIYHLNPSGRFVIGGPQGDAGLTGRKIIVDTYXXXXXXXXXXXXXKDATKVDRSAAYAARWVAKSLVKNGLCKRVLVQFSYAIGIAAPLSIFVYSYNSSTKTDNELLAIVNQNFDLRPGAIIRDLKLREPIFEKTASYGHFGRNEFLWENPKKLHF 1202
            E D FLFTSESVGEGHPDKICDQISDAILDAHLKQDP AK+ACE+  KTGM+L+ GE+TSHAVV+Y  +VR+TI++IG+D S KG DY+TCNVLVA+EQQSPDIAQGV+++R+E+ IGAGDQGLMFGYATDETEECMP+T+ILAHKLN ++A  RRN  L WLRPD+KTQVT+ Y+   G +LP+ VHTIVIS QHDEE+ LE ++  L + VI  V+ S  L   TIYHL PSGRFVIGGPQGDAGLTGRKIIVDTYGGWGAHGGGAFSGKD TKVDRSAAYAARWVAKSLVK GLC+RVLVQ SYAIG+A PLSI ++ Y +S K++ ELL IV +NFDLRPG I+RDL L++PI++KTA+YGHFGR+ F WE PKKL +
Sbjct:   15 EEDCFLFTSESVGEGHPDKICDQISDAILDAHLKQDPDAKIACETVAKTGMILLAGEVTSHAVVDYQKVVRDTIRQIGYDDSSKGFDYKTCNVLVALEQQSPDIAQGVHIDRNEEDIGAGDQGLMFGYATDETEECMPLTIILAHKLNAKMADLRRNGTLPWLRPDSKTQVTVQYRQDRGAMLPVRVHTIVISVQHDEEICLEEMRDALKEKVIKTVVPSVYLDDDTIYHLQPSGRFVIGGPQGDAGLTGRKIIVDTYGGWGAHGGGAFSGKDYTKVDRSAAYAARWVAKSLVKAGLCRRVLVQVSYAIGVAHPLSISIFHYGTSKKSERELLDIVRKNFDLRPGVIVRDLDLKKPIYQKTAAYGHFGRDSFPWELPKKLKY 396
[Close]
BLAST of S-adenosylmethionine synthase vs. Ensembl Cavefish
Match: mat2ab (S-adenosylmethionine synthase [Source:NCBI gene;Acc:103044681])

HSP 1 Score: 551.206 bits (1419), Expect = 0.000e+0
Identity = 265/382 (69.37%), Postives = 322/382 (84.29%), Query Frame = 3 
Query:   57 ENDIFLFTSESVGEGHPDKICDQISDAILDAHLKQDPYAKVACESFTKTGMVLVGGEITSHAVVNYSDIVRNTIKRIGFDSSEKGLDYRTCNVLVAIEQQSPDIAQGVYVNRSEDSIGAGDQGLMFGYATDETEECMPMTLILAHKLNQRLAYCRRNDILGWLRPDTKTQVTIAYKNKDGGLLPLYVHTIVISAQHDEEVTLENIKSDLMKHVISNVIDSKMLTSSTIYHLNPSGRFVIGGPQGDAGLTGRKIIVDTYXXXXXXXXXXXXXKDATKVDRSAAYAARWVAKSLVKNGLCKRVLVQFSYAIGIAAPLSIFVYSYNSSTKTDNELLAIVNQNFDLRPGAIIRDLKLREPIFEKTASYGHFGRNEFLWENPKKLHF 1202
            + D FLFTSESVGEGHPDKICDQISDA+LDAHLKQDP AKVACE+  KTGM+L+ GE+TS A V+Y  +VR+TI+ IG+D S KG DY+TCNVLVA+EQQSPDIAQGV+++R+++ +GAGDQGLMFGYATDETEECMP+T++LAHKLN ++A  RRN +L WLRPD+KTQVT+ Y+   G +LP+ VHTIV+S QHDE++ L+ ++  L + V+  V+    L   TIYHL PSGRFVIGGPQGDAGLTGRKIIVDTYGGWGAHGGGAFSGKD TKVDRSAAYAARWVAKSLVK  LC+RVLVQ SYAIG+A PLSI ++ Y +S K++ ELL IV +NFDLRPG I+RDL+LR+PI+++TA+YGHFGR+ F WE PKKL +
Sbjct:   19 DEDCFLFTSESVGEGHPDKICDQISDAVLDAHLKQDPDAKVACETVAKTGMILLAGEVTSRATVDYQKVVRDTIRHIGYDDSTKGFDYKTCNVLVALEQQSPDIAQGVHLDRNQEDVGAGDQGLMFGYATDETEECMPLTIVLAHKLNAKMAELRRNGVLPWLRPDSKTQVTVQYRQDRGAMLPVRVHTIVVSVQHDEDICLDEMRDALKEKVVKAVVPCVYLDDDTIYHLQPSGRFVIGGPQGDAGLTGRKIIVDTYGGWGAHGGGAFSGKDYTKVDRSAAYAARWVAKSLVKAELCRRVLVQVSYAIGVAHPLSISIFHYGTSQKSERELLDIVRKNFDLRPGVIVRDLQLRKPIYQRTAAYGHFGRDSFSWEIPKKLQY 400
[Close]
BLAST of S-adenosylmethionine synthase vs. Ensembl Cavefish
Match: mat1a (S-adenosylmethionine synthase [Source:NCBI gene;Acc:103041217])

HSP 1 Score: 548.51 bits (1412), Expect = 0.000e+0
Identity = 270/378 (71.43%), Postives = 321/378 (84.92%), Query Frame = 3 
Query:   69 FLFTSESVGEGHPDKICDQISDAILDAHLKQDPYAKVACESFTKTGMVLVGGEITSHAVVNYSDIVRNTIKRIGFDSSEKGLDYRTCNVLVAIEQQSPDIAQGVYVNRSEDSIGAGDQGLMFGYATDETEECMPMTLILAHKLNQRLAYCRRNDILGWLRPDTKTQVTIAYKNKDGGLLPLYVHTIVISAQHDEEVTLENIKSDLMKHVISNVIDSKMLTSSTIYHLNPSGRFVIGGPQGDAGLTGRKIIVDTYXXXXXXXXXXXXXKDATKVDRSAAYAARWVAKSLVKNGLCKRVLVQFSYAIGIAAPLSIFVYSYNSSTKTDNELLAIVNQNFDLRPGAIIRDLKLREPIFEKTASYGHFGRNEFLWENPKKLHF 1202
            F+FTSESVGEGHPDKICDQISDA+LDAHL+QDP AKVACE+  KTGMVL+ GEITS A V+Y  +VR+TIK IG+D+S+KG DY+TCNVLVA+EQQSPDIAQGV+++R E+ IGAGDQGLMFGYATDETEECMP+T++LAHKLN ++A  RR+  + WLRPD+KTQVT+ YK ++G ++PL VHT+VIS QHD+ ++LE  +  L + VI  V+ +K L   T+YHL PSGRFVIGGPQGDAG+TGRKIIVDTYGGWGAHGGGAFSGKD TKVDRSAAYAARWVAKSLV   LCKRVLVQ SYAIG+A PLSI +++Y SS KT+ ELL IVN+NFDLRPG I+RDLKL+ PI++ TA YGHFGR+EF WE PK L F
Sbjct:   13 FMFTSESVGEGHPDKICDQISDAVLDAHLRQDPDAKVACETVCKTGMVLLCGEITSRANVDYQKVVRDTIKHIGYDNSDKGFDYKTCNVLVALEQQSPDIAQGVHIDRHEEDIGAGDQGLMFGYATDETEECMPLTIVLAHKLNSKMAELRRDGTIPWLRPDSKTQVTVHYKQENGAVIPLRVHTVVISVQHDDLISLEEQQRILKEKVIKAVVPAKYLDDKTVYHLQPSGRFVIGGPQGDAGVTGRKIIVDTYGGWGAHGGGAFSGKDYTKVDRSAAYAARWVAKSLVMAKLCKRVLVQVSYAIGVAHPLSISLFTYGSSEKTEKELLQIVNKNFDLRPGVIVRDLKLKRPIYQDTACYGHFGRSEFPWEVPKTLKF 390
[Close]
BLAST of S-adenosylmethionine synthase vs. Ensembl Cavefish
Match: mat1a (S-adenosylmethionine synthase [Source:NCBI gene;Acc:103041217])

HSP 1 Score: 538.88 bits (1387), Expect = 0.000e+0
Identity = 270/389 (69.41%), Postives = 321/389 (82.52%), Query Frame = 3 
Query:   69 FLFTSESVGEGHPDKICDQISDAILDAHLKQDPYAKVACESFTKTGMVLVGGEITSHAVVNYSDIVRNTIKRIGFDSSEKGLDYRTCNVLVAIEQQSPDIAQGVYVNRSEDSIGAGDQGLMFGYATDETEECMPMTLILAHKLNQRLAYCRRNDILGWLRPDTKTQVTIAYKNKDGGLLPLYVHTIVISAQHDEEVTLENIKSDLMKHVISNVIDSKMLTSSTIYHLNPSGRFVIGGPQGDAGLTGRKIIVDTYXXXXXXXXXXXXXKDATKVDRSAAYAARWVAKSLVKNGLCKRVLVQFSYAIGIAAPLSIFVYSYNSSTKTDNELLAIVNQNFDLRPGAII-----------RDLKLREPIFEKTASYGHFGRNEFLWENPKKLHF 1202
            F+FTSESVGEGHPDKICDQISDA+LDAHL+QDP AKVACE+  KTGMVL+ GEITS A V+Y  +VR+TIK IG+D+S+KG DY+TCNVLVA+EQQSPDIAQGV+++R E+ IGAGDQGLMFGYATDETEECMP+T++LAHKLN ++A  RR+  + WLRPD+KTQVT+ YK ++G ++PL VHT+VIS QHD+ ++LE  +  L + VI  V+ +K L   T+YHL PSGRFVIGGPQGDAG+TGRKIIVDTYGGWGAHGGGAFSGKD TKVDRSAAYAARWVAKSLV   LCKRVLVQ SYAIG+A PLSI +++Y SS KT+ ELL IVN+NFDLRPG I+           RDLKL+ PI++ TA YGHFGR+EF WE PK L F
Sbjct:   13 FMFTSESVGEGHPDKICDQISDAVLDAHLRQDPDAKVACETVCKTGMVLLCGEITSRANVDYQKVVRDTIKHIGYDNSDKGFDYKTCNVLVALEQQSPDIAQGVHIDRHEEDIGAGDQGLMFGYATDETEECMPLTIVLAHKLNSKMAELRRDGTIPWLRPDSKTQVTVHYKQENGAVIPLRVHTVVISVQHDDLISLEEQQRILKEKVIKAVVPAKYLDDKTVYHLQPSGRFVIGGPQGDAGVTGRKIIVDTYGGWGAHGGGAFSGKDYTKVDRSAAYAARWVAKSLVMAKLCKRVLVQVSYAIGVAHPLSISLFTYGSSEKTEKELLQIVNKNFDLRPGVIVRVFQTWAVNNYRDLKLKRPIYQDTACYGHFGRSEFPWEVPKTLKF 401
[Close]
BLAST of S-adenosylmethionine synthase vs. Ensembl Cavefish
Match: mat2aa (S-adenosylmethionine synthase [Source:NCBI gene;Acc:103039813])

HSP 1 Score: 536.954 bits (1382), Expect = 0.000e+0
Identity = 269/382 (70.42%), Postives = 319/382 (83.51%), Query Frame = 3 
Query:   57 ENDIFLFTSESVGEGHPDKICDQISDAILDAHLKQDPYAKVACESFTKTGMVLVGGEITSHAVVNYSDIVRNTIKRIGFDSSEKGLDYRTCNVLVAIEQQSPDIAQGVYVNRSEDSIGAGDQGLMFGYATDETEECMPMTLILAHKLNQRLAYCRRNDILGWLRPDTKTQVTIAYKNKDGGLLPLYVHTIVISAQHDEEVTLENIKSDLMKHVISNVIDSKMLTSSTIYHLNPSGRFVIGGPQGDAGLTGRKIIVDTYXXXXXXXXXXXXXKDATKVDRSAAYAARWVAKSLVKNGLCKRVLVQFSYAIGIAAPLSIFVYSYNSSTKTDNELLAIVNQNFDLRPGAIIRDLKLREPIFEKTASYGHFGRNEFLWENPKKLHF 1202
            E D FLFTSESVGEGHPDKICDQISDA+LDAHLKQDP AKVACE+  KTGM+L+ GE+TS A V+Y  +VR+ IK IG+D S KG DY+TCNVLVA+EQQSPDIAQGV+++R+E+ IGAGDQGLMFGYATDETEECMP+T++LAHKLN ++A  RRN  L WLRPD+KTQVT+ Y+   G +LP+ VHT+V+S QHDE V L+ ++  L + V+  V+ S  L   TIYHL PSGRFVIGGPQGDAGLTGRKIIVDTYGGWGAHGGGAFSGKD TKVDRSAAYAARWVAKSLVK GLCKRVLVQ SYAIG+A PLSI ++ Y +S +++ ELL IV +NFDLRPG I+RDL L++PI+++TA+YGHFGR  F WE PKKL +
Sbjct:   14 EEDCFLFTSESVGEGHPDKICDQISDAVLDAHLKQDPDAKVACETVAKTGMILLAGEVTSRACVDYQKVVRDAIKHIGYDDSSKGFDYKTCNVLVALEQQSPDIAQGVHLDRNEEDIGAGDQGLMFGYATDETEECMPLTIVLAHKLNAKMAELRRNGTLPWLRPDSKTQVTVQYRQDRGAMLPVRVHTVVVSVQHDEVVCLDEMRDALKEKVVKAVVPSVYLDDDTIYHLQPSGRFVIGGPQGDAGLTGRKIIVDTYGGWGAHGGGAFSGKDYTKVDRSAAYAARWVAKSLVKAGLCKRVLVQVSYAIGVAHPLSISIFHYGTSQRSEKELLDIVKKNFDLRPGVIVRDLDLKKPIYQRTAAYGHFGRESFPWEVPKKLKY 395
[Close]
BLAST of S-adenosylmethionine synthase vs. Ensembl Cavefish
Match: mat2al (S-adenosylmethionine synthase [Source:NCBI gene;Acc:103022635])

HSP 1 Score: 471.855 bits (1213), Expect = 7.468e-166
Identity = 236/379 (62.27%), Postives = 294/379 (77.57%), Query Frame = 3 
Query:   69 FLFTSESVGEGHPDKICDQISDAILDAHLKQDPYAKVACESFTKTGMVLVGGEITSHAVVNYSDIVRNTIKRIGFDSSEKGLDYRTCNVLVAIEQQSPDIAQGVYVNRSEDSIGAGDQGLMFGYATDETEECMPMTLILAHKLNQRLAYCRRNDILGWLRPDTKTQVTIAYKNKDGGLLPLYVHTIVISAQHDEEVTLENIKSDLMKHVISNVIDSKMLTSSTIYHLNPSGRFVIGGPQ-GDAGLTGRKIIVDTYXXXXXXXXXXXXXKDATKVDRSAAYAARWVAKSLVKNGLCKRVLVQFSYAIGIAAPLSIFVYSYNSSTKTDNELLAIVNQNFDLRPGAIIRDLKLREPIFEKTASYGHFGRNEFLWENPKKLHF 1202
            FLFTSESVG+GH DK+CDQISDA+LDA+L QDP AKVACE   KTGM+L+ GE+TS AVV+   +VR+T+K IG+D S KG DY+TCNVLVA++ Q  +I   V+  R E+ IGAGDQG MFGYATDET+ECMP+T++LAHKLN ++    +N    W+ PD+K+QVT+ Y++  G + P+ VHT+VIS QH  ++TL  I+ +LM+ V+  VI +K L   TIYHL PSG+F+IGGPQ        RKIIVDTYGGWG HGGGAFSGKD +KVDRS AYAARWVAKSLVK  LC+RVLVQ SYAIGI+ PLSI V+ Y +ST+ ++ELL IV +NFDLRPG I+++L L+ PI++KTASYGHFGR EF WE PKKL F
Sbjct:   13 FLFTSESVGQGHSDKMCDQISDAVLDAYLSQDPDAKVACECVAKTGMILLCGEVTSKAVVDLEKVVRDTVKDIGYDDSSKGFDYKTCNVLVALQPQCEEITDCVFEGRDEEDIGAGDQGFMFGYATDETDECMPLTILLAHKLNHKMKELSKNGECAWILPDSKSQVTVEYRDNMGVMEPIRVHTVVISVQHTPDITLSEIRKNLMEKVVKTVIPAKYLDDRTIYHLLPSGKFLIGGPQVKKCRPYWRKIIVDTYGGWGGHGGGAFSGKDYSKVDRSGAYAARWVAKSLVKAKLCRRVLVQISYAIGISHPLSISVFHYGTSTRDEDELLEIVQKNFDLRPGVIVKELGLKRPIYQKTASYGHFGREEFPWEKPKKLVF 391
[Close]
BLAST of S-adenosylmethionine synthase vs. Ensembl Yeast
Match: SAM2 (S-adenosylmethionine synthetase; catalyzes transfer of the adenosyl group of ATP to the sulfur atom of methionine; comparative analysis suggests that a mitochondrially targeted form may result from translation starting at a non-canonical codon upstream of the annotated start codon [Source:SGD;Acc:S000002910])

HSP 1 Score: 504.982 bits (1299), Expect = 6.800e-180
Identity = 244/384 (63.54%), Postives = 308/384 (80.21%), Query Frame = 3 
Query:   51 MDENDIFLFTSESVGEGHPDKICDQISDAILDAHLKQDPYAKVACESFTKTGMVLVGGEITSHAVVNYSDIVRNTIKRIGFDSSEKGLDYRTCNVLVAIEQQSPDIAQGVYVNRSEDSIGAGDQGLMFGYATDETEECMPMTLILAHKLNQRLAYCRRNDILGWLRPDTKTQVTIAYKNKDGGLLPLYVHTIVISAQHDEEVTLENIKSDLMKHVISNVIDSKMLTSSTIYHLNPSGRFVIGGPQGDAGLTGRKIIVDTYXXXXXXXXXXXXXKDATKVDRSAAYAARWVAKSLVKNGLCKRVLVQFSYAIGIAAPLSIFVYSYNSSTKTDNELLAIVNQNFDLRPGAIIRDLKLREPIFEKTASYGHFGRNEFLWENPKKLHF 1202
            M ++  FLFTSESVGEGHPDKICDQ+SDAILDA L+QDP++KVACE+  KTGM++V GEIT+ A ++Y  IVR+TIK+IG+D S KG DY+TCNVLVAIEQQSPDIAQG++  +S + +GAGDQG+MFGYATDET E +P+T++LAHKLN  +A  RR+  L WLRPDTKTQVT+ Y++ +G  +P  + T+VISAQH +E++  ++++ L K ++  VI   ML  +T Y + PSGRFVIGGPQGDAGLTGRKIIVD YGG  + GGGAFSGKD +KVDRSAAYAARWVAKSLV  GLCKRV VQFSYAIGIA PLS+ V +Y ++TK+D+E++ I+ +NFDLRPG ++++L L  PI+  TASYGHF   E+ WE PKKL F
Sbjct:    1 MSKSKTFLFTSESVGEGHPDKICDQVSDAILDACLEQDPFSKVACETAAKTGMIMVFGEITTKARLDYQQIVRDTIKKIGYDDSAKGFDYKTCNVLVAIEQQSPDIAQGLHYEKSLEDLGAGDQGIMFGYATDETPEGLPLTILLAHKLNMAMADARRDGSLPWLRPDTKTQVTVEYEDDNGRWVPKRIDTVVISAQHADEISTADLRTQLQKDIVEKVIPKDMLDENTKYFIQPSGRFVIGGPQGDAGLTGRKIIVDAYGGASSVGGGAFSGKDYSKVDRSAAYAARWVAKSLVAAGLCKRVQVQFSYAIGIAEPLSLHVDTYGTATKSDDEIIEIIKKNFDLRPGVLVKELDLARPIYLPTASYGHFTNQEYSWEKPKKLEF 384
[Close]
BLAST of S-adenosylmethionine synthase vs. Ensembl Yeast
Match: SAM1 (S-adenosylmethionine synthetase; catalyzes transfer of the adenosyl group of ATP to the sulfur atom of methionine; SAM1 has a paralog, SAM2, that arose from the whole genome duplication [Source:SGD;Acc:S000004170])

HSP 1 Score: 500.36 bits (1287), Expect = 4.910e-178
Identity = 244/378 (64.55%), Postives = 301/378 (79.63%), Query Frame = 3 
Query:   69 FLFTSESVGEGHPDKICDQISDAILDAHLKQDPYAKVACESFTKTGMVLVGGEITSHAVVNYSDIVRNTIKRIGFDSSEKGLDYRTCNVLVAIEQQSPDIAQGVYVNRSEDSIGAGDQGLMFGYATDETEECMPMTLILAHKLNQRLAYCRRNDILGWLRPDTKTQVTIAYKNKDGGLLPLYVHTIVISAQHDEEVTLENIKSDLMKHVISNVIDSKMLTSSTIYHLNPSGRFVIGGPQGDAGLTGRKIIVDTYXXXXXXXXXXXXXKDATKVDRSAAYAARWVAKSLVKNGLCKRVLVQFSYAIGIAAPLSIFVYSYNSSTKTDNELLAIVNQNFDLRPGAIIRDLKLREPIFEKTASYGHFGRNEFLWENPKKLHF 1202
            FLFTSESVGEGHPDKICDQ+SDAILDA L +DP++KVACE+  KTGM++V GEIT+ A ++Y  IVR+TIK+IG+D S KG DY+TCNVLVAIEQQSPDIAQGV+  +  + IGAGDQG+MFGYATDET E +P+T++LAHKLN  +A  RR+  L WLRPDTKTQVT+ YK+  G  +P  + T+V+SAQH +E+T E++++ L   +I  VI   ML  +T Y + PSGRFVIGGPQGDAGLTGRKIIVD YGG  + GGGAFSGKD +KVDRSAAYAARWVAKSLV  GLCKRV VQFSYAIGIA PLS+ V +Y ++TK+D E++ I+++NFDLRPG ++++L L  PI+  TASYGHF   E+ WE PK L F
Sbjct:    5 FLFTSESVGEGHPDKICDQVSDAILDACLAEDPHSKVACETAAKTGMIMVFGEITTKAQLDYQKIVRDTIKKIGYDDSAKGFDYKTCNVLVAIEQQSPDIAQGVHEEKDLEDIGAGDQGIMFGYATDETPEGLPLTILLAHKLNMAMADARRDGSLAWLRPDTKTQVTVEYKDDHGRWVPQRIDTVVVSAQHADEITTEDLRAQLKSEIIEKVIPRDMLDENTKYFIQPSGRFVIGGPQGDAGLTGRKIIVDAYGGASSVGGGAFSGKDYSKVDRSAAYAARWVAKSLVAAGLCKRVQVQFSYAIGIAEPLSLHVDTYGTATKSDEEIIDIISKNFDLRPGVLVKELDLARPIYLPTASYGHFTNQEYPWEKPKTLKF 382
[Close]
BLAST of S-adenosylmethionine synthase vs. Ensembl Nematostella
Match: EDO37850 (S-adenosylmethionine synthase [Source:UniProtKB/TrEMBL;Acc:A7SEP5])

HSP 1 Score: 533.487 bits (1373), Expect = 0.000e+0
Identity = 263/382 (68.85%), Postives = 316/382 (82.72%), Query Frame = 3 
Query:   57 ENDIFLFTSESVGEGHPDKICDQISDAILDAHLKQDPYAKVACESFTKTGMVLVGGEITSHAVVNYSDIVRNTIKRIGFDSSEKGLDYRTCNVLVAIEQQSPDIAQGVYVNRSEDSIGAGDQGLMFGYATDETEECMPMTLILAHKLNQRLAYCRRNDILGWLRPDTKTQVTIAYKNKDGGLLPLYVHTIVISAQHDEEVTLENIKSDLMKHVISNVIDSKMLTSSTIYHLNPSGRFVIGGPQGDAGLTGRKIIVDTYXXXXXXXXXXXXXKDATKVDRSAAYAARWVAKSLVKNGLCKRVLVQFSYAIGIAAPLSIFVYSYNSSTKTDNELLAIVNQNFDLRPGAIIRDLKLREPIFEKTASYGHFGRNEFLWENPKKLHF 1202
            +N+ FLFTSESVGEGHPDK+CDQISDAILDAHLKQDP AKVACE+  KTGM+L+ GEITS+AVV+Y  +VR  IK IG+D SEKG DY+TCNVLVA+EQQS DIA GV+V R E+ +GAGDQGLMFGYATDETEE MP+T++LAHK+NQ+LA  RR+  L W RPD+KTQVT+ YK + G  +PL VHTIVIS QHD  +T+EN++ +LM+ ++  V+ SK L   TI+HL PSG FVIGGPQGDAGLTGRKIIVDTYGGWGAHGGGAFSGKD TKVDRSAAYAARW+AKSLV  GLCKRVLVQ SYAIGIA PLS+ V+SY +S K+++ELL IV  NFDLRPG I+++L L++P+++K+  YGHF +  F WE PK L +
Sbjct:   27 QNNTFLFTSESVGEGHPDKMCDQISDAILDAHLKQDPNAKVACETVAKTGMILLCGEITSNAVVDYQSVVRQCIKDIGYDDSEKGFDYKTCNVLVALEQQSVDIAHGVHVGREEEDVGAGDQGLMFGYATDETEELMPLTVVLAHKMNQKLAEYRRDGTLPWARPDSKTQVTVEYKFEHGRAIPLRVHTIVISVQHDPTITMENLRKELMEKIVKTVVPSKFLDEDTIFHLQPSGLFVIGGPQGDAGLTGRKIIVDTYGGWGAHGGGAFSGKDYTKVDRSAAYAARWIAKSLVSEGLCKRVLVQISYAIGIAQPLSVTVFSYGTSKKSEDELLKIVRDNFDLRPGKIVKELDLKKPVYQKSCVYGHF-KPGFTWETPKPLQY 407
[Close]
BLAST of S-adenosylmethionine synthase vs. Ensembl Nematostella
Match: EDO37825 (S-adenosylmethionine synthase [Source:UniProtKB/TrEMBL;Acc:A7SEP6])

HSP 1 Score: 513.842 bits (1322), Expect = 0.000e+0
Identity = 255/381 (66.93%), Postives = 309/381 (81.10%), Query Frame = 3 
Query:   60 NDIFLFTSESVGEGHPDKICDQISDAILDAHLKQDPYAKVACESFTKTGMVLVGGEITSHAVVNYSDIVRNTIKRIGFDSSEKGLDYRTCNVLVAIEQQSPDIAQGVYVNRSEDSIGAGDQGLMFGYATDETEECMPMTLILAHKLNQRLAYCRRNDILGWLRPDTKTQVTIAYKNKDGGLLPLYVHTIVISAQHDEEVTLENIKSDLMKHVISNVIDSKMLTSSTIYHLNPSGRFVIGGPQGDAGLTGRKIIVDTYXXXXXXXXXXXXXKDATKVDRSAAYAARWVAKSLVKNGLCKRVLVQFSYAIGIAAPLSIFVYSYNSSTKTDNELLAIVNQNFDLRPGAIIRDLKLREPIFEKTASYGHFGRNEFLWENPKKLHF 1202
            N+ FLFTSESVGEGHPDK+CDQISDAILDAHLKQDP AKVACES  KTGM++V GEITS A V+Y  +VR+TIK+IG+D S KG DY+TC VL AIEQQSPDIAQGV++ RS++ +GAGDQGLMFGYATDET+E MP+T++LAH LN+RLA CRRN  L W+RPD+KTQVT+ YK + G  +PL VHTIVIS QHD  + L+ ++ +LM +V+  V+  K + + T+YH+ PSG FVIGGPQGDAGLTGRKIIVDTYGGWGAHGGGAFSGKD +KVDRSAAYAARW+AKSLV   LC RVLVQ SYAIG+A PLSI V++Y +  + + ELL ++  NFDLRPG I+RDL L++PI++ T  YGHF +  F WE PK L +
Sbjct:    8 NNTFLFTSESVGEGHPDKMCDQISDAILDAHLKQDPNAKVACESVAKTGMIVVCGEITSLANVDYQKVVRDTIKQIGYDDSSKGFDYKTCTVLQAIEQQSPDIAQGVHIGRSDEDLGAGDQGLMFGYATDETDELMPLTVVLAHGLNKRLADCRRNGSLPWVRPDSKTQVTVEYKFQGGKAVPLRVHTIVISVQHDPNIELDVMRKELMDYVVKEVVPEKYIDNDTVYHMQPSGSFVIGGPQGDAGLTGRKIIVDTYGGWGAHGGGAFSGKDPSKVDRSAAYAARWIAKSLVAAKLCHRVLVQLSYAIGVAEPLSISVFTYGTGYRPEEELLEVIKHNFDLRPGVIVRDLDLKKPIYQSTCLYGHF-KPGFPWEVPKPLKY 387
[Close]
BLAST of S-adenosylmethionine synthase vs. Ensembl Nematostella
Match: EDO45117 (S-adenosylmethionine synthase [Source:UniProtKB/TrEMBL;Acc:A7RTZ9])

HSP 1 Score: 481.871 bits (1239), Expect = 1.284e-169
Identity = 246/378 (65.08%), Postives = 299/378 (79.10%), Query Frame = 3 
Query:   63 DIFLFTSESVGEGHPDKICDQISDAILDAHLKQDPYAKVACESFTKTGMVLVGGEITSHAVVNYSDIVRNTIKRIGFDSSEKGLDYRTCNVLVAIEQQSPDIAQGVYVNRSEDSIGAGDQGLMFGYATDETEECMPMTLILAHKLNQRLAYCRRNDILGWLRPDTKTQVTIAYKNKDGGLLPLYVHTIVISAQHDEEVTLENIKSDLMKHVISNVIDSKMLTSSTIYHLNPSGRFVIGGPQGDAGLTGRKIIVDTYXXXXXXXXXXXXXKDATKVDRSAAYAARWVAKSLVKNGLCKRVLVQFSYAIGIAAPLSIFVYSYNSSTKTDNELLAIVNQNFDLRPGAIIRDLKLREPIFEKTASYGHFGRNEFLWENPKKL 1196
            D FLFTSESV EGH DK+CDQISDA+LDAHL+QDPYAKVACE+ TKTG+VL+ GEITS+A V+Y  +VRNTI+ IG++ S  G DY+TC+VL+AI++Q  +IAQ V++NR +D IGAGDQGLMFGYATDETEE MP+T +LAHKL  RLA CR+  IL WL PD KTQVT+ Y+ + G  +P  VHT++IS QH  +V +E I+  L + +I++VI  K L   TI+HL PSG+F+ GGP GDAGLTGRKIIVDTYGGWGAHGGGAFSGKD TKVDRS AYA RW+AKSLV  GLC+RVLVQ +YAIGIA PLSI V+SY S   TD +LL ++  NFDLRPG IIRDL L  PI++ T+++GHF +  F WE PKKL
Sbjct:   50 DNFLFTSESVNEGHSDKMCDQISDAVLDAHLEQDPYAKVACETATKTGLVLLFGEITSNARVDYQAVVRNTIRDIGYNDSSTGFDYKTCSVLLAIQEQVAEIAQTVHLNRRDDEIGAGDQGLMFGYATDETEELMPLTTVLAHKLCARLAECRKGKILPWLLPDGKTQVTVDYRLERGACIPERVHTVLISTQHTPDVGIEEIRHHLKETIINHVIPEKYLDDKTIFHLLPSGQFIDGGPLGDAGLTGRKIIVDTYGGWGAHGGGAFSGKDVTKVDRSGAYACRWIAKSLVAAGLCRRVLVQVAYAIGIAEPLSISVFSYGSGNYTDKQLLGVIKDNFDLRPGVIIRDLNLLRPIYKATSTFGHF-KPGFPWEEPKKL 426
[Close]
BLAST of S-adenosylmethionine synthase vs. Ensembl Nematostella
Match: EDO26870 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7TAU6])

HSP 1 Score: 199.134 bits (505), Expect = 4.811e-62
Identity = 114/212 (53.77%), Postives = 150/212 (70.75%), Query Frame = 3 
Query:  345 IEQQSPDIAQGVYVNRSEDSIGAGDQGLMFGYATDETEECMPMTLILAHKLNQRLAYCRRNDILGWLRPDTKTQVTIAYKNKDGGLLPLYVHTIVISAQHDEEVTLENIKSDLMKHVISNVIDSKMLTSSTIYHLNPSGRFVIGGPQGDAGLTGRKIIVDTYXXXXXXXXXXXXXKDATKVDRSAAYAARWVAKSLVKNGLCKRVLVQFSYA 980
            I +QS DI QGV   + ED  GAGDQGLMFGYAT+ET+  MP  +  AH+L +R +  RRN  L WLRPD K+QVTI ++    G  P  V  +V+S QHD  ++L++++  +++++I  V+ ++ L   T+YH+NP+G FVIGGP GDAGLTGRKIIVDTYGG   HGGGAFSGKD +KVDRSAAY  R+VAK++V   L  +  +Q SYA
Sbjct:    1 IGKQSVDINQGVDRAKPEDQ-GAGDQGLMFGYATNETDSLMPAPVYYAHRLVERQSELRRNGTLPWLRPDAKSQVTINWE----GDSP-KVDAVVLSTQHDPSISLDDLREAVLENIIKPVLPAEWLHEGTLYHINPTGNFVIGGPVGDAGLTGRKIIVDTYGGMARHGGGAFSGKDPSKVDRSAAYIGRYVAKNIVAAELADKCEIQVSYA 206
[Close]
BLAST of S-adenosylmethionine synthase vs. Ensembl Medaka
Match: mat2ab (S-adenosylmethionine synthase [Source:NCBI gene;Acc:101160913])

HSP 1 Score: 557.755 bits (1436), Expect = 0.000e+0
Identity = 271/382 (70.94%), Postives = 321/382 (84.03%), Query Frame = 3 
Query:   57 ENDIFLFTSESVGEGHPDKICDQISDAILDAHLKQDPYAKVACESFTKTGMVLVGGEITSHAVVNYSDIVRNTIKRIGFDSSEKGLDYRTCNVLVAIEQQSPDIAQGVYVNRSEDSIGAGDQGLMFGYATDETEECMPMTLILAHKLNQRLAYCRRNDILGWLRPDTKTQVTIAYKNKDGGLLPLYVHTIVISAQHDEEVTLENIKSDLMKHVISNVIDSKMLTSSTIYHLNPSGRFVIGGPQGDAGLTGRKIIVDTYXXXXXXXXXXXXXKDATKVDRSAAYAARWVAKSLVKNGLCKRVLVQFSYAIGIAAPLSIFVYSYNSSTKTDNELLAIVNQNFDLRPGAIIRDLKLREPIFEKTASYGHFGRNEFLWENPKKLHF 1202
            E D FLFTSESVGEGHPDKICDQISDA+LDAHLKQDP AKVACE+  KTGM+L+ GE+TS A V+Y  +VR+TI++IG+D S KG DY+TCNVLVA+EQQSPDIAQGV+++RSE+ IGAGDQGLMFGYATDETEECMP+T++LAHKLN ++A  RRN  L WLRPD+KTQVT+ Y+   G +LP+ VHTIV+S QHDE++ LE ++  L + VI  V+    L   TIYHL PSGRFVIGGPQGDAGLTGRKIIVDTYGGWGAHGGGAFSGKD TKVDRSAAYAARWVAKSLVK GLC+RVLVQ SYAIG+A PLSI ++ Y +S K++ ELL IV +NFDLRPG I+RDL L++P ++KTA+YGHFGR+ F WE PKKL +
Sbjct:   15 EEDCFLFTSESVGEGHPDKICDQISDAVLDAHLKQDPDAKVACETVAKTGMILLAGEVTSRATVDYQKVVRDTIRQIGYDDSSKGFDYKTCNVLVALEQQSPDIAQGVHIDRSEEEIGAGDQGLMFGYATDETEECMPLTIVLAHKLNAKMAELRRNGTLPWLRPDSKTQVTVQYRQDRGAMLPVRVHTIVVSVQHDEDICLEEMRDALKEKVIKAVVPCVYLDDDTIYHLQPSGRFVIGGPQGDAGLTGRKIIVDTYGGWGAHGGGAFSGKDYTKVDRSAAYAARWVAKSLVKAGLCRRVLVQVSYAIGVAHPLSISIFHYGTSKKSERELLDIVRKNFDLRPGVIVRDLDLKKPFYQKTAAYGHFGRDSFPWEVPKKLKY 396
[Close]
BLAST of S-adenosylmethionine synthase vs. Ensembl Medaka
Match: mat1a (S-adenosylmethionine synthase [Source:NCBI gene;Acc:101160342])

HSP 1 Score: 557.37 bits (1435), Expect = 0.000e+0
Identity = 277/384 (72.14%), Postives = 328/384 (85.42%), Query Frame = 3 
Query:   51 MDENDIFLFTSESVGEGHPDKICDQISDAILDAHLKQDPYAKVACESFTKTGMVLVGGEITSHAVVNYSDIVRNTIKRIGFDSSEKGLDYRTCNVLVAIEQQSPDIAQGVYVNRSEDSIGAGDQGLMFGYATDETEECMPMTLILAHKLNQRLAYCRRNDILGWLRPDTKTQVTIAYKNKDGGLLPLYVHTIVISAQHDEEVTLENIKSDLMKHVISNVIDSKMLTSSTIYHLNPSGRFVIGGPQGDAGLTGRKIIVDTYXXXXXXXXXXXXXKDATKVDRSAAYAARWVAKSLVKNGLCKRVLVQFSYAIGIAAPLSIFVYSYNSSTKTDNELLAIVNQNFDLRPGAIIRDLKLREPIFEKTASYGHFGRNEFLWENPKKLHF 1202
            +D+N  F+FTSESVGEGHPDKICDQISDA+LDAHLKQDP AKVACE+  KTGMVL+ GEITS A V+Y  +VR+TIK IG+D+S+KG DY+TCNVLVA+EQQSPDIAQGV+V+R E+ IGAGDQGLMFGYATDETEECMP+T++LAHKLN ++A  RRN  + WLRPD+KTQVT+ Y+ KDG ++P  VHTIVIS QHD+ VTLE  +  L + VI  V+ +K L   TI HL PSGRFVIGGPQGDAG+TGRKIIVDTYGGWGAHGGGAFSGKD +KVDRSAAYAARWVAKSLVK  LC+RVLVQ SYAIG+A PLSI +++Y SS KT++ELL IVN+NFDLRPG I+RDL+L+ PI+++TA+YGHFGR+EF WE PKKL F
Sbjct:    5 LDDNS-FMFTSESVGEGHPDKICDQISDAVLDAHLKQDPDAKVACETVCKTGMVLLCGEITSRANVDYQKVVRDTIKHIGYDNSDKGFDYKTCNVLVALEQQSPDIAQGVHVDRQEEDIGAGDQGLMFGYATDETEECMPLTIVLAHKLNAKMAELRRNGTVPWLRPDSKTQVTVHYEQKDGAVIPKRVHTIVISVQHDDGVTLEEQQKALKEKVIKAVVPAKYLDDKTICHLQPSGRFVIGGPQGDAGVTGRKIIVDTYGGWGAHGGGAFSGKDFSKVDRSAAYAARWVAKSLVKAKLCRRVLVQVSYAIGVAQPLSISLFTYGSSKKTESELLKIVNKNFDLRPGVIVRDLQLKRPIYQQTAAYGHFGRSEFSWEVPKKLVF 387
[Close]
BLAST of S-adenosylmethionine synthase vs. Ensembl Medaka
Match: ENSORLT00000016106.2 (S-adenosylmethionine synthase [Source:NCBI gene;Acc:101159865])

HSP 1 Score: 544.658 bits (1402), Expect = 0.000e+0
Identity = 269/378 (71.16%), Postives = 316/378 (83.60%), Query Frame = 3 
Query:   69 FLFTSESVGEGHPDKICDQISDAILDAHLKQDPYAKVACESFTKTGMVLVGGEITSHAVVNYSDIVRNTIKRIGFDSSEKGLDYRTCNVLVAIEQQSPDIAQGVYVNRSEDSIGAGDQGLMFGYATDETEECMPMTLILAHKLNQRLAYCRRNDILGWLRPDTKTQVTIAYKNKDGGLLPLYVHTIVISAQHDEEVTLENIKSDLMKHVISNVIDSKMLTSSTIYHLNPSGRFVIGGPQGDAGLTGRKIIVDTYXXXXXXXXXXXXXKDATKVDRSAAYAARWVAKSLVKNGLCKRVLVQFSYAIGIAAPLSIFVYSYNSSTKTDNELLAIVNQNFDLRPGAIIRDLKLREPIFEKTASYGHFGRNEFLWENPKKLHF 1202
            FLFTSESVGEGHPDK+CDQISDA+LDAHL QDP AKVACE+  KTGMVL+ GEITS A V+Y  +VR+ IK IG+DSS KGLDY+TCNVLVA+E+QSPDIAQGV+V+R E  IGAGDQGLMFGYATDETEECMP+T++LAHKLN R+A  RRN  + WLRPD+KTQVT+ Y  + G ++P  +HT+VIS QHD+ V+LE  +S LM+ VI  VI +K L  +T+YHL PSGRFVIGGPQGDAG+TGRKIIVDTYGGWGAHGGGAFSGKD TKVDRSAAYAARWVAKSLV   LC+RVLVQ +YAIG+A PLSI ++++ SS K++ ELL IV +NFDLRPG I+RDL L+ PI++KTA YGHFGR EF WE PK L F
Sbjct:   20 FLFTSESVGEGHPDKMCDQISDAVLDAHLSQDPDAKVACETVCKTGMVLLCGEITSRASVDYQKVVRDVIKHIGYDSSSKGLDYKTCNVLVALEEQSPDIAQGVHVDRMESEIGAGDQGLMFGYATDETEECMPLTIVLAHKLNARMAELRRNGTVPWLRPDSKTQVTVHYSQESGAVIPERIHTVVISVQHDDHVSLEEQRSVLMEKVIRAVIPAKYLDENTVYHLQPSGRFVIGGPQGDAGVTGRKIIVDTYGGWGAHGGGAFSGKDYTKVDRSAAYAARWVAKSLVNARLCRRVLVQVAYAIGVAHPLSISLFTFGSSQKSEKELLQIVYRNFDLRPGVIVRDLDLKRPIYQKTACYGHFGRKEFPWEVPKNLEF 397
[Close]
BLAST of S-adenosylmethionine synthase vs. Ensembl Medaka
Match: ENSORLT00000011581.2 (S-adenosylmethionine synthase [Source:NCBI gene;Acc:101171015])

HSP 1 Score: 539.265 bits (1388), Expect = 0.000e+0
Identity = 263/384 (68.49%), Postives = 319/384 (83.07%), Query Frame = 3 
Query:   51 MDENDIFLFTSESVGEGHPDKICDQISDAILDAHLKQDPYAKVACESFTKTGMVLVGGEITSHAVVNYSDIVRNTIKRIGFDSSEKGLDYRTCNVLVAIEQQSPDIAQGVYVNRSEDSIGAGDQGLMFGYATDETEECMPMTLILAHKLNQRLAYCRRNDILGWLRPDTKTQVTIAYKNKDGGLLPLYVHTIVISAQHDEEVTLENIKSDLMKHVISNVIDSKMLTSSTIYHLNPSGRFVIGGPQGDAGLTGRKIIVDTYXXXXXXXXXXXXXKDATKVDRSAAYAARWVAKSLVKNGLCKRVLVQFSYAIGIAAPLSIFVYSYNSSTKTDNELLAIVNQNFDLRPGAIIRDLKLREPIFEKTASYGHFGRNEFLWENPKKLHF 1202
            + + D FLFTSESVGEGHPDKICDQISDA+LDAHL QDP AKVACE+  KTGM+L+ GEITS A V+Y  +VR+ I+ IG+D S KG DY+TCNVLVA+EQQSPDIAQGV+++R E+ +GAGDQGLMFGYATDET+ECMP+T++LAHKLN ++A  RR+  L WLRPD+KTQVT+ YK   G ++PL VHTIVIS QHDE V LE ++  L + V+  V+ S  L   TIYHL PSGRFVIGGPQGDAGLTGRKIIVDTYGGWGAHGGGAFSGKD TKVDRSAAYAARWVAKSLVK+ LC+RVLVQ SYAIG++ PLS+ ++ Y +S +++ ELL IV +NFDLRPG I+R+L L++PI+++TA+YGHFGR+ F WE PKKL +
Sbjct:    9 LHDKDCFLFTSESVGEGHPDKICDQISDAVLDAHLSQDPDAKVACETVAKTGMILLAGEITSRAKVDYQKVVRDAIRDIGYDDSSKGFDYKTCNVLVALEQQSPDIAQGVHLDRKEEDVGAGDQGLMFGYATDETDECMPLTIVLAHKLNAKMAELRRDGTLPWLRPDSKTQVTVQYKQDRGAVVPLRVHTIVISVQHDECVCLEEMRRCLKEQVVKAVVPSGYLDDETIYHLQPSGRFVIGGPQGDAGLTGRKIIVDTYGGWGAHGGGAFSGKDYTKVDRSAAYAARWVAKSLVKSNLCRRVLVQVSYAIGVSHPLSVSIFHYGTSQRSERELLDIVMKNFDLRPGVIVRELDLKKPIYQRTAAYGHFGRDVFSWEMPKKLKY 392
[Close]
BLAST of S-adenosylmethionine synthase vs. Ensembl Medaka
Match: mat2al (S-adenosylmethionine synthase [Source:NCBI gene;Acc:101170772])

HSP 1 Score: 491.5 bits (1264), Expect = 1.610e-173
Identity = 240/378 (63.49%), Postives = 300/378 (79.37%), Query Frame = 3 
Query:   69 FLFTSESVGEGHPDKICDQISDAILDAHLKQDPYAKVACESFTKTGMVLVGGEITSHAVVNYSDIVRNTIKRIGFDSSEKGLDYRTCNVLVAIEQQSPDIAQGVYVNRSEDSIGAGDQGLMFGYATDETEECMPMTLILAHKLNQRLAYCRRNDILGWLRPDTKTQVTIAYKNKDGGLLPLYVHTIVISAQHDEEVTLENIKSDLMKHVISNVIDSKMLTSSTIYHLNPSGRFVIGGPQGDAGLTGRKIIVDTYXXXXXXXXXXXXXKDATKVDRSAAYAARWVAKSLVKNGLCKRVLVQFSYAIGIAAPLSIFVYSYNSSTKTDNELLAIVNQNFDLRPGAIIRDLKLREPIFEKTASYGHFGRNEFLWENPKKLHF 1202
            FLFTSESVGEGH DK+CDQISDA+LDA+L QDP +KVACE   KTGM+L+ GE+TS A V+   +VRNTIK+IG+DSS KG DY+TCNVLVA+E Q+ +I+  V+  R+++ IGAGDQGLMFGYATDETEECMP+T++LAHKLN ++    RN    W+ PD K+QVT+ Y++  G + PL VHT+VIS QH  +++LE I+ +LM+ V+  VI +K L   T+YHL PSG+F++GGPQGDAGLTGRKIIVDTYGGWG HGGGAFSGKD +KVDRS AYAARWVAKSLVK GLC+R LVQ SY+I ++ PLSI V+ Y +S++ ++ELL IV  NFDLRPG I+ +L L+ PI++ TA YGHFGR EF WE PK L F
Sbjct:   13 FLFTSESVGEGHSDKMCDQISDAVLDAYLSQDPDSKVACECVAKTGMILLVGEVTSRAKVDLQAVVRNTIKKIGYDSSSKGFDYKTCNVLVALEPQAQEISDCVFEGRNQEDIGAGDQGLMFGYATDETEECMPLTILLAHKLNHKMKELSRNGDCPWILPDCKSQVTVEYRDDAGAMEPLRVHTVVISVQHSPDISLEEIRHNLMEKVVKAVIPAKYLDDQTVYHLLPSGKFLLGGPQGDAGLTGRKIIVDTYGGWGGHGGGAFSGKDYSKVDRSGAYAARWVAKSLVKAGLCRRALVQISYSIAVSHPLSITVFHYGTSSRDEDELLQIVKDNFDLRPGVIVTELGLKRPIYQATACYGHFGREEFPWEKPKPLVF 390
[Close]
BLAST of S-adenosylmethionine synthase vs. Planmine SMEST
Match: SMESG000013953.1 (SMESG000013953.1)

HSP 1 Score: 767.303 bits (1980), Expect = 0.000e+0
Identity = 385/385 (100.00%), Postives = 385/385 (100.00%), Query Frame = 3 
Query:   51 MDENDIFLFTSESVGEGHPDKICDQISDAILDAHLKQDPYAKVACESFTKTGMVLVGGEITSHAVVNYSDIVRNTIKRIGFDSSEKGLDYRTCNVLVAIEQQSPDIAQGVYVNRSEDSIGAGDQGLMFGYATDETEECMPMTLILAHKLNQRLAYCRRNDILGWLRPDTKTQVTIAYKNKDGGLLPLYVHTIVISAQHDEEVTLENIKSDLMKHVISNVIDSKMLTSSTIYHLNPSGRFVIGGPQGDAGLTGRKIIVDTYXXXXXXXXXXXXXKDATKVDRSAAYAARWVAKSLVKNGLCKRVLVQFSYAIGIAAPLSIFVYSYNSSTKTDNELLAIVNQNFDLRPGAIIRDLKLREPIFEKTASYGHFGRNEFLWENPKKLHFK 1205
            MDENDIFLFTSESVGEGHPDKICDQISDAILDAHLKQDPYAKVACESFTKTGMVLVGGEITSHAVVNYSDIVRNTIKRIGFDSSEKGLDYRTCNVLVAIEQQSPDIAQGVYVNRSEDSIGAGDQGLMFGYATDETEECMPMTLILAHKLNQRLAYCRRNDILGWLRPDTKTQVTIAYKNKDGGLLPLYVHTIVISAQHDEEVTLENIKSDLMKHVISNVIDSKMLTSSTIYHLNPSGRFVIGGPQGDAGLTGRKIIVDTYGGWGAHGGGAFSGKDATKVDRSAAYAARWVAKSLVKNGLCKRVLVQFSYAIGIAAPLSIFVYSYNSSTKTDNELLAIVNQNFDLRPGAIIRDLKLREPIFEKTASYGHFGRNEFLWENPKKLHFK
Sbjct:    1 MDENDIFLFTSESVGEGHPDKICDQISDAILDAHLKQDPYAKVACESFTKTGMVLVGGEITSHAVVNYSDIVRNTIKRIGFDSSEKGLDYRTCNVLVAIEQQSPDIAQGVYVNRSEDSIGAGDQGLMFGYATDETEECMPMTLILAHKLNQRLAYCRRNDILGWLRPDTKTQVTIAYKNKDGGLLPLYVHTIVISAQHDEEVTLENIKSDLMKHVISNVIDSKMLTSSTIYHLNPSGRFVIGGPQGDAGLTGRKIIVDTYGGWGAHGGGAFSGKDATKVDRSAAYAARWVAKSLVKNGLCKRVLVQFSYAIGIAAPLSIFVYSYNSSTKTDNELLAIVNQNFDLRPGAIIRDLKLREPIFEKTASYGHFGRNEFLWENPKKLHFK 385
[Close]
BLAST of S-adenosylmethionine synthase vs. Planmine SMEST
Match: SMESG000053202.1 (SMESG000053202.1)

HSP 1 Score: 567.385 bits (1461), Expect = 0.000e+0
Identity = 277/380 (72.89%), Postives = 324/380 (85.26%), Query Frame = 3 
Query:   63 DIFLFTSESVGEGHPDKICDQISDAILDAHLKQDPYAKVACESFTKTGMVLVGGEITSHAVVNYSDIVRNTIKRIGFDSSEKGLDYRTCNVLVAIEQQSPDIAQGVYVNRSEDSIGAGDQGLMFGYATDETEECMPMTLILAHKLNQRLAYCRRNDILGWLRPDTKTQVTIAYKNKDGGLLPLYVHTIVISAQHDEEVTLENIKSDLMKHVISNVIDSKMLTSSTIYHLNPSGRFVIGGPQGDAGLTGRKIIVDTYXXXXXXXXXXXXXKDATKVDRSAAYAARWVAKSLVKNGLCKRVLVQFSYAIGIAAPLSIFVYSYNSSTKTDNELLAIVNQNFDLRPGAIIRDLKLREPIFEKTASYGHFGRNEFLWENPKKLHF 1202
            + FLFTSESVGEGHPDKICDQ+SDA+LDAHL QDP AKVACE+F+KTGM+L+GGEITS+A+VNY  ++R TIK IGFDS EKG DY+TCN+L+AIEQQ+P+IAQ V+  RS++ IGAGDQGLMFGYATDETEECMP+T++LAH LN +LA CRRN+ L +LRPDTKTQVT+ YK+ +G  +PL VHTIVIS QHDE + +  ++ DLM+HV+  VI  K L +STIYHLNPSGRFVIGGPQGDAGLTGRKIIVDTYGGWGAHGGGAFSGKD +KVDRS AYAARWVAKSLVK GLC+RVLVQ SYAIGIAAPLSIFV SY + +  D++LL I+N NFDLRPG I +DL LR PI++KTA YGHFGR EF WE PK L +
Sbjct:   14 ETFLFTSESVGEGHPDKICDQVSDAVLDAHLSQDPKAKVACETFSKTGMILIGGEITSNAIVNYQRVIRQTIKDIGFDSCEKGFDYKTCNLLIAIEQQNPEIAQSVHEERSDEDIGAGDQGLMFGYATDETEECMPLTVVLAHGLNMKLAECRRNNTLPYLRPDTKTQVTVLYKSVNGACIPLKVHTIVISTQHDENIHINQLRKDLMEHVVKTVIPEKYLDASTIYHLNPSGRFVIGGPQGDAGLTGRKIIVDTYGGWGAHGGGAFSGKDYSKVDRSGAYAARWVAKSLVKAGLCRRVLVQLSYAIGIAAPLSIFVDSYGTGSIPDSQLLEIINDNFDLRPGHIEKDLDLRRPIYQKTACYGHFGRPEFTWEQPKTLKY 393
[Close]
BLAST of S-adenosylmethionine synthase vs. Planmine SMEST
Match: SMESG000027587.1 (SMESG000027587.1)

HSP 1 Score: 562.762 bits (1449), Expect = 0.000e+0
Identity = 278/381 (72.97%), Postives = 322/381 (84.51%), Query Frame = 3 
Query:   60 NDIFLFTSESVGEGHPDKICDQISDAILDAHLKQDPYAKVACESFTKTGMVLVGGEITSHAVVNYSDIVRNTIKRIGFDSSEKGLDYRTCNVLVAIEQQSPDIAQGVYVNRSEDSIGAGDQGLMFGYATDETEECMPMTLILAHKLNQRLAYCRRNDILGWLRPDTKTQVTIAYKNKDGGLLPLYVHTIVISAQHDEEVTLENIKSDLMKHVISNVIDSKMLTSSTIYHLNPSGRFVIGGPQGDAGLTGRKIIVDTYXXXXXXXXXXXXXKDATKVDRSAAYAARWVAKSLVKNGLCKRVLVQFSYAIGIAAPLSIFVYSYNSSTKTDNELLAIVNQNFDLRPGAIIRDLKLREPIFEKTASYGHFGRNEFLWENPKKLHF 1202
            ++ FLFTSESVGEGHPDKICDQISDAILDAHLKQDP AKVACE+F KTGM+LVGGEI+S AVV+Y  +VR TIK IG+D  EKG DY+TCNVL+AIE+QSPDIAQGV++ R  D+IGAGDQGLMFGYATDET ECMP+T++LAH LN+RL+ CRRN  L WLRPDTKTQVT+ YK+ +G  +PL VHT+VIS QHDE ++ ++++  L+K +I  VI    L   TIYHLNPSGRFVIGGPQGDAGLTGRKIIVDTYGGWGAHGGGAFSGKD +KVDRSAAYAARWVAKSLVK GLC+RVLVQ SYAIG+A PLSI+V SY +S+ +D ELL IV  NFDLRPG I+++L LR PI++KTA YGHFGR EF WE PKKL F
Sbjct:    6 SNTFLFTSESVGEGHPDKICDQISDAILDAHLKQDPNAKVACETFAKTGMILVGGEISSKAVVDYQKVVRETIKEIGYDHCEKGFDYKTCNVLLAIEEQSPDIAQGVHLERDFDNIGAGDQGLMFGYATDETAECMPLTVVLAHALNKRLSECRRNGTLPWLRPDTKTQVTVEYKSDNGACIPLRVHTVVISTQHDETISHQHLQQCLIKEIIKKVIPEHYLDEETIYHLNPSGRFVIGGPQGDAGLTGRKIIVDTYGGWGAHGGGAFSGKDFSKVDRSAAYAARWVAKSLVKAGLCRRVLVQVSYAIGVAHPLSIYVDSYGTSSHSDAELLRIVVDNFDLRPGHIVKELNLRHPIYKKTACYGHFGREEFTWEKPKKLKF 386
The following BLAST results are available for this feature:
BLAST of S-adenosylmethionine synthase vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 4
Match NameE-valueIdentityDescription
MAT2A0.000e+070.94methionine adenosyltransferase 2A [Source:HGNC Sym... [more]
MAT1A0.000e+070.71methionine adenosyltransferase 1A [Source:HGNC Sym... [more]
MAT2A2.525e-14670.23methionine adenosyltransferase 2A [Source:HGNC Sym... [more]
MAT1A5.499e-7157.53methionine adenosyltransferase 1A [Source:HGNC Sym... [more]
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BLAST of S-adenosylmethionine synthase vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
sams-30.000e+067.20Probable S-adenosylmethionine synthase 3 [Source:... [more]
sams-40.000e+066.76Probable S-adenosylmethionine synthase 4 [Source:... [more]
sams-40.000e+066.76Probable S-adenosylmethionine synthase 4 [Source:... [more]
sams-51.942e-18066.49Probable S-adenosylmethionine synthase 5 [Source:... [more]
sams-51.942e-18066.49Probable S-adenosylmethionine synthase 5 [Source:... [more]
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BLAST of S-adenosylmethionine synthase vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Sam-S0.000e+067.02gene:FBgn0005278 transcript:FBtr0089430[more]
Sam-S0.000e+067.02gene:FBgn0005278 transcript:FBtr0089433[more]
Sam-S0.000e+067.02gene:FBgn0005278 transcript:FBtr0089432[more]
Sam-S0.000e+067.02gene:FBgn0005278 transcript:FBtr0089429[more]
Sam-S0.000e+067.02gene:FBgn0005278 transcript:FBtr0089434[more]
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BLAST of S-adenosylmethionine synthase vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
mat2aa0.000e+070.16methionine adenosyltransferase II, alpha a [Source... [more]
mat1a0.000e+071.54methionine adenosyltransferase I, alpha [Source:ZF... [more]
mat1a0.000e+071.54methionine adenosyltransferase I, alpha [Source:ZF... [more]
mat2ab1.293e-18071.92methionine adenosyltransferase II, alpha b [Source... [more]
mat2al4.891e-17362.96methionine adenosyltransferase II, alpha-like [Sou... [more]
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BLAST of S-adenosylmethionine synthase vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
mat1a0.000e+071.96methionine adenosyltransferase I, alpha [Source:NC... [more]
use10.000e+070.37unconventional SNARE in the ER 1 homolog [Source:X... [more]
use10.000e+070.37unconventional SNARE in the ER 1 homolog [Source:X... [more]
mat1a0.000e+071.07methionine adenosyltransferase I, alpha [Source:NC... [more]
use10.000e+069.32unconventional SNARE in the ER 1 homolog [Source:X... [more]
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BLAST of S-adenosylmethionine synthase vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Mat1a0.000e+070.31methionine adenosyltransferase I, alpha [Source:MG... [more]
Mat1a0.000e+070.31methionine adenosyltransferase I, alpha [Source:MG... [more]
Mat2a0.000e+070.94methionine adenosyltransferase II, alpha [Source:M... [more]
Mat2a0.000e+070.94methionine adenosyltransferase II, alpha [Source:M... [more]
Mat2a1.338e-17971.92methionine adenosyltransferase II, alpha [Source:M... [more]
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BLAST of S-adenosylmethionine synthase vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q91X83|METK1_MOUSE0.000e+070.31S-adenosylmethionine synthase isoform type-1 OS=Mu... [more]
sp|Q5R5H1|METK2_PONAB0.000e+070.94S-adenosylmethionine synthase isoform type-2 OS=Po... [more]
sp|Q4R924|METK2_MACFA0.000e+070.94S-adenosylmethionine synthase isoform type-2 OS=Ma... [more]
sp|P31153|METK2_HUMAN0.000e+070.94S-adenosylmethionine synthase isoform type-2 OS=Ho... [more]
sp|Q3THS6|METK2_MOUSE0.000e+070.94S-adenosylmethionine synthase isoform type-2 OS=Mu... [more]
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BLAST of S-adenosylmethionine synthase vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A1I8HKQ40.000e+073.02S-adenosylmethionine synthase OS=Macrostomum ligna... [more]
A0A1I8I6050.000e+073.02S-adenosylmethionine synthase OS=Macrostomum ligna... [more]
A0A267DP280.000e+073.02S-adenosylmethionine synthase OS=Macrostomum ligna... [more]
H9G9N00.000e+072.32S-adenosylmethionine synthase OS=Anolis carolinens... [more]
A0A1A7Z0I60.000e+072.51S-adenosylmethionine synthase OS=Iconisemion stria... [more]
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BLAST of S-adenosylmethionine synthase vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
mat2ab0.000e+069.37S-adenosylmethionine synthase [Source:NCBI gene;Ac... [more]
mat1a0.000e+071.43S-adenosylmethionine synthase [Source:NCBI gene;Ac... [more]
mat1a0.000e+069.41S-adenosylmethionine synthase [Source:NCBI gene;Ac... [more]
mat2aa0.000e+070.42S-adenosylmethionine synthase [Source:NCBI gene;Ac... [more]
mat2al7.468e-16662.27S-adenosylmethionine synthase [Source:NCBI gene;Ac... [more]
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BLAST of S-adenosylmethionine synthase vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of S-adenosylmethionine synthase vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 2
Match NameE-valueIdentityDescription
SAM26.800e-18063.54S-adenosylmethionine synthetase; catalyzes transfe... [more]
SAM14.910e-17864.55S-adenosylmethionine synthetase; catalyzes transfe... [more]
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BLAST of S-adenosylmethionine synthase vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 4
Match NameE-valueIdentityDescription
EDO378500.000e+068.85S-adenosylmethionine synthase [Source:UniProtKB/T... [more]
EDO378250.000e+066.93S-adenosylmethionine synthase [Source:UniProtKB/T... [more]
EDO451171.284e-16965.08S-adenosylmethionine synthase [Source:UniProtKB/T... [more]
EDO268704.811e-6253.77Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of S-adenosylmethionine synthase vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
mat2ab0.000e+070.94S-adenosylmethionine synthase [Source:NCBI gene;Ac... [more]
mat1a0.000e+072.14S-adenosylmethionine synthase [Source:NCBI gene;Ac... [more]
ENSORLT00000016106.20.000e+071.16S-adenosylmethionine synthase [Source:NCBI gene;Ac... [more]
ENSORLT00000011581.20.000e+068.49S-adenosylmethionine synthase [Source:NCBI gene;Ac... [more]
mat2al1.610e-17363.49S-adenosylmethionine synthase [Source:NCBI gene;Ac... [more]
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BLAST of S-adenosylmethionine synthase vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 3
Match NameE-valueIdentityDescription
SMESG000013953.10.000e+0100.00SMESG000013953.1[more]
SMESG000053202.10.000e+072.89SMESG000053202.1[more]
SMESG000027587.10.000e+072.97SMESG000027587.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30028293 ID=SMED30028293|Name=S-adenosylmethionine synthase|organism=Schmidtea mediterranea sexual|type=transcript|length=1272bp
CAGGTTTTATTTAAATTATAGCTTTAATTGTTTACGAAAATTAAGAATAG
ATGGATGAAAACGACATTTTTCTTTTTACTTCTGAATCTGTCGGAGAAGG
TCATCCAGATAAAATTTGTGATCAAATTAGTGATGCTATACTAGATGCGC
ATTTGAAGCAAGATCCTTATGCAAAAGTTGCATGTGAATCATTTACGAAA
ACTGGAATGGTTTTAGTTGGTGGAGAAATAACTTCTCATGCAGTAGTAAA
TTATTCAGATATTGTACGAAATACTATAAAGAGGATTGGGTTTGATAGTT
CAGAGAAAGGATTAGATTATAGAACTTGCAATGTTTTAGTTGCAATTGAG
CAACAAAGTCCTGATATAGCCCAAGGTGTTTATGTTAACAGATCTGAAGA
TAGTATTGGTGCAGGGGATCAAGGACTTATGTTTGGATATGCAACTGATG
AAACGGAAGAGTGCATGCCTATGACTTTGATTTTGGCTCATAAGTTAAAT
CAGCGTCTAGCCTATTGCAGACGAAATGATATACTTGGCTGGTTGAGACC
AGATACGAAAACTCAAGTAACCATAGCATATAAAAACAAAGATGGGGGCC
TATTACCATTGTATGTACACACAATTGTTATATCTGCTCAACATGATGAA
GAAGTCACACTGGAAAATATTAAATCTGATCTAATGAAACATGTTATTAG
TAATGTTATTGATTCTAAAATGCTTACATCAAGCACAATCTATCACTTAA
ATCCTTCTGGAAGATTTGTTATTGGTGGCCCTCAAGGTGATGCTGGCTTG
ACCGGTAGAAAAATTATCGTGGATACTTATGGAGGTTGGGGAGCTCATGG
TGGAGGTGCATTTTCCGGTAAAGATGCCACTAAAGTAGATAGATCTGCAG
CATATGCTGCGAGGTGGGTGGCTAAATCCTTAGTTAAAAATGGTTTGTGT
AAAAGAGTCCTTGTTCAGTTCTCATACGCAATCGGAATTGCAGCTCCATT
GTCTATATTTGTGTACAGTTATAATTCTAGTACAAAAACCGACAATGAAT
TATTGGCAATAGTTAATCAAAATTTTGATTTGCGACCCGGTGCTATAATA
AGAGACCTGAAATTGCGTGAGCCCATTTTTGAAAAAACCGCAAGTTACGG
ACATTTTGGTAGAAATGAATTTCTGTGGGAAAATCCGAAAAAACTTCACT
TTAAATAAATTTTACTTTTGAATTTTTTATTTATCATTTAATTAATTAAT
TTAGTTGATTAATTGATTATCT
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protein sequence of SMED30028293-orf-1

>SMED30028293-orf-1 ID=SMED30028293-orf-1|Name=SMED30028293-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=386bp
MDENDIFLFTSESVGEGHPDKICDQISDAILDAHLKQDPYAKVACESFTK
TGMVLVGGEITSHAVVNYSDIVRNTIKRIGFDSSEKGLDYRTCNVLVAIE
QQSPDIAQGVYVNRSEDSIGAGDQGLMFGYATDETEECMPMTLILAHKLN
QRLAYCRRNDILGWLRPDTKTQVTIAYKNKDGGLLPLYVHTIVISAQHDE
EVTLENIKSDLMKHVISNVIDSKMLTSSTIYHLNPSGRFVIGGPQGDAGL
TGRKIIVDTYGGWGAHGGGAFSGKDATKVDRSAAYAARWVAKSLVKNGLC
KRVLVQFSYAIGIAAPLSIFVYSYNSSTKTDNELLAIVNQNFDLRPGAII
RDLKLREPIFEKTASYGHFGRNEFLWENPKKLHFK*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000020protonephridia
PLANA:0002109X1 cell
Vocabulary: INTERPRO
TermDefinition
IPR022629S-AdoMet_synt_central
IPR002133S-AdoMet_synthetase
IPR022628S-AdoMet_synt_N
IPR022630S-AdoMet_synt_C
IPR022631ADOMET_SYNTHASE_CS
IPR022636S-AdoMet_synthetase_sfam
Vocabulary: biological process
TermDefinition
GO:0006556S-adenosylmethionine biosynthetic process
GO:0006730one-carbon metabolic process
Vocabulary: molecular function
TermDefinition
GO:0004478methionine adenosyltransferase activity
GO:0005524ATP binding
GO:0000166nucleotide binding
GO:0016740transferase activity
GO:0046872metal ion binding
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
NoneNo IPR availableGENE3DG3DSA:3.30.300.10coord: 8..243
e-value: 5.8E-169
score: 563.9
NoneNo IPR availableGENE3DG3DSA:3.30.300.10coord: 14..280
e-value: 5.8E-169
score: 563.9
NoneNo IPR availableGENE3DG3DSA:3.30.300.10coord: 118..377
e-value: 5.8E-169
score: 563.9
NoneNo IPR availablePANTHERPTHR11964:SF11S-ADENOSYLMETHIONINE SYNTHASE ISOFORM TYPE-1coord: 2..384
NoneNo IPR availableCDDcd18079S-AdoMet_syntcoord: 8..380
e-value: 0.0
score: 667.569
IPR002133S-adenosylmethionine synthetasePIRSFPIRSF000497MATcoord: 1..385
e-value: 1.3E-161
score: 535.5
IPR002133S-adenosylmethionine synthetaseTIGRFAMTIGR01034TIGR01034coord: 8..383
e-value: 5.4E-175
score: 579.8
IPR002133S-adenosylmethionine synthetasePANTHERPTHR11964S-ADENOSYLMETHIONINE SYNTHETASEcoord: 2..384
IPR022628S-adenosylmethionine synthetase, N-terminalPFAMPF00438S-AdoMet_synt_Ncoord: 7..104
e-value: 6.3E-42
score: 142.3
IPR022630S-adenosylmethionine synthetase, C-terminalPFAMPF02773S-AdoMet_synt_Ccoord: 241..377
e-value: 5.7E-66
score: 220.7
IPR022629S-adenosylmethionine synthetase, central domainPFAMPF02772S-AdoMet_synt_Mcoord: 119..239
e-value: 3.4E-44
score: 150.0
IPR022631S-adenosylmethionine synthetase, conserved sitePROSITEPS00377ADOMET_SYNTHASE_2coord: 267..275
IPR022631S-adenosylmethionine synthetase, conserved sitePROSITEPS00376ADOMET_SYNTHASE_1coord: 120..130
IPR022636S-adenosylmethionine synthetase superfamilySUPERFAMILYSSF55973S-adenosylmethionine synthetasecoord: 117..240
IPR022636S-adenosylmethionine synthetase superfamilySUPERFAMILYSSF55973S-adenosylmethionine synthetasecoord: 241..383
IPR022636S-adenosylmethionine synthetase superfamilySUPERFAMILYSSF55973S-adenosylmethionine synthetasecoord: 7..112