Polyglutamine-binding protein 1

Overview
NamePolyglutamine-binding protein 1
Smed IDSMED30028254
Length (bp)1106
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Polyglutamine-binding protein 1 (SMED30028254) t-SNE clustered cells

Violin plots show distribution of expression levels for Polyglutamine-binding protein 1 (SMED30028254) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Polyglutamine-binding protein 1 (SMED30028254) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Polyglutamine-binding protein 1 (SMED30028254) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30028254

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 4

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
protonephridiaSMED30028254h1SMcG0010665 dd_Smed_v4_3489_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
muscle cellSMED30028254h1SMcG0010665 dd_Smed_v4_3489_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
neoblastSMED30028254h1SMcG0010665 dd_Smed_v4_3489_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymal cellSMED30028254h1SMcG0010665 dd_Smed_v4_3489_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Polyglutamine-binding protein 1 vs. Ensembl Human
Match: PQBP1 (polyglutamine binding protein 1 [Source:HGNC Symbol;Acc:HGNC:9330])

HSP 1 Score: 83.5741 bits (205), Expect = 8.386e-19
Identity = 37/49 (75.51%), Postives = 41/49 (83.67%), Query Frame = 1 
Query:  847 AYSDAPRGTWKTGLDVRGSAKTGVDSTASGPLFQQRPYPSPGEILRQNA 993
            +YSDAPRGTW TGL  R  AKTG D+TA+GPLFQQRPYPSPG +LR NA
Sbjct:  102 SYSDAPRGTWSTGLPKRNEAKTGADTTAAGPLFQQRPYPSPGAVLRANA 150

HSP 2 Score: 48.1358 bits (113), Expect = 3.375e-6
Identity = 21/47 (44.68%), Postives = 28/47 (59.57%), Query Frame = 1 
Query:  463 LPPNWIEVADPSTNRFYYWNTKKDEVCWLSPTHPRSIIRLPKDKVKA 603
            LPP+W +V DPS    YYWN   D V WLSP  P S++     K+++
Sbjct:   37 LPPSWYKVFDPSCGLPYYWNADTDLVSWLSPHDPNSVVTKSAKKLRS 83
[Close]
BLAST of Polyglutamine-binding protein 1 vs. Ensembl Human
Match: PQBP1 (polyglutamine binding protein 1 [Source:HGNC Symbol;Acc:HGNC:9330])

HSP 1 Score: 83.5741 bits (205), Expect = 1.403e-18
Identity = 37/49 (75.51%), Postives = 41/49 (83.67%), Query Frame = 1 
Query:  847 AYSDAPRGTWKTGLDVRGSAKTGVDSTASGPLFQQRPYPSPGEILRQNA 993
            +YSDAPRGTW TGL  R  AKTG D+TA+GPLFQQRPYPSPG +LR NA
Sbjct:  113 SYSDAPRGTWSTGLPKRNEAKTGADTTAAGPLFQQRPYPSPGAVLRANA 161

HSP 2 Score: 48.1358 bits (113), Expect = 4.088e-6
Identity = 20/38 (52.63%), Postives = 24/38 (63.16%), Query Frame = 1 
Query:  463 LPPNWIEVADPSTNRFYYWNTKKDEVCWLSPTHPRSII 576
            LPP+W +V DPS    YYWN   D V WLSP  P S++
Sbjct:   48 LPPSWYKVFDPSCGLPYYWNADTDLVSWLSPHDPNSVV 85
[Close]
BLAST of Polyglutamine-binding protein 1 vs. Ensembl Human
Match: PQBP1 (polyglutamine binding protein 1 [Source:HGNC Symbol;Acc:HGNC:9330])

HSP 1 Score: 83.5741 bits (205), Expect = 1.403e-18
Identity = 37/49 (75.51%), Postives = 41/49 (83.67%), Query Frame = 1 
Query:  847 AYSDAPRGTWKTGLDVRGSAKTGVDSTASGPLFQQRPYPSPGEILRQNA 993
            +YSDAPRGTW TGL  R  AKTG D+TA+GPLFQQRPYPSPG +LR NA
Sbjct:  113 SYSDAPRGTWSTGLPKRNEAKTGADTTAAGPLFQQRPYPSPGAVLRANA 161

HSP 2 Score: 48.1358 bits (113), Expect = 4.088e-6
Identity = 20/38 (52.63%), Postives = 24/38 (63.16%), Query Frame = 1 
Query:  463 LPPNWIEVADPSTNRFYYWNTKKDEVCWLSPTHPRSII 576
            LPP+W +V DPS    YYWN   D V WLSP  P S++
Sbjct:   48 LPPSWYKVFDPSCGLPYYWNADTDLVSWLSPHDPNSVV 85
[Close]
BLAST of Polyglutamine-binding protein 1 vs. Ensembl Human
Match: PQBP1 (polyglutamine binding protein 1 [Source:HGNC Symbol;Acc:HGNC:9330])

HSP 1 Score: 84.3445 bits (207), Expect = 4.797e-18
Identity = 37/49 (75.51%), Postives = 41/49 (83.67%), Query Frame = 1 
Query:  847 AYSDAPRGTWKTGLDVRGSAKTGVDSTASGPLFQQRPYPSPGEILRQNA 993
            +YSDAPRGTW TGL  R  AKTG D+TA+GPLFQQRPYPSPG +LR NA
Sbjct:  208 SYSDAPRGTWSTGLPKRNEAKTGADTTAAGPLFQQRPYPSPGAVLRANA 256

HSP 2 Score: 48.1358 bits (113), Expect = 9.298e-6
Identity = 20/38 (52.63%), Postives = 24/38 (63.16%), Query Frame = 1 
Query:  463 LPPNWIEVADPSTNRFYYWNTKKDEVCWLSPTHPRSII 576
            LPP+W +V DPS    YYWN   D V WLSP  P S++
Sbjct:   48 LPPSWYKVFDPSCGLPYYWNADTDLVSWLSPHDPNSVV 85
[Close]
BLAST of Polyglutamine-binding protein 1 vs. Ensembl Human
Match: PQBP1 (polyglutamine binding protein 1 [Source:HGNC Symbol;Acc:HGNC:9330])

HSP 1 Score: 84.3445 bits (207), Expect = 4.797e-18
Identity = 37/49 (75.51%), Postives = 41/49 (83.67%), Query Frame = 1 
Query:  847 AYSDAPRGTWKTGLDVRGSAKTGVDSTASGPLFQQRPYPSPGEILRQNA 993
            +YSDAPRGTW TGL  R  AKTG D+TA+GPLFQQRPYPSPG +LR NA
Sbjct:  208 SYSDAPRGTWSTGLPKRNEAKTGADTTAAGPLFQQRPYPSPGAVLRANA 256

HSP 2 Score: 48.1358 bits (113), Expect = 9.298e-6
Identity = 20/38 (52.63%), Postives = 24/38 (63.16%), Query Frame = 1 
Query:  463 LPPNWIEVADPSTNRFYYWNTKKDEVCWLSPTHPRSII 576
            LPP+W +V DPS    YYWN   D V WLSP  P S++
Sbjct:   48 LPPSWYKVFDPSCGLPYYWNADTDLVSWLSPHDPNSVV 85
[Close]
BLAST of Polyglutamine-binding protein 1 vs. Ensembl Celegans
Match: pqbp-1.1 (PQBP1 (Polyglutamine tract-binding neurodegeneration protein) homolog [Source:UniProtKB/TrEMBL;Acc:O16786])

HSP 1 Score: 109.383 bits (272), Expect = 2.466e-27
Identity = 59/154 (38.31%), Postives = 88/154 (57.14%), Query Frame = 1 
Query:  148 MSLPPALLARLKKRGINVENKKEMKEEIFAESYDEDNKVQSAINELKDTSIIDVRYIVYEVANCPNLSNPYHKCVEYCIEKYEKKKFNPDLLM----IKKRNTMLKKYPLPPNWIEVADPSTNRFYYWNTKKDEVCWLSPTHPRSIIRLPKDKV 597
            M LPPALLARL+KRGI      + +EE+ AE+Y+++ + +S     ++ S             CPN  N YH C+E+C + +      P+  +    ++ +N ML K+PLP NW+EV D    ++Y+WN   DEVCW SP HPR+II  P  ++
Sbjct:    1 MPLPPALLARLQKRGI-----VKQEEEVIAENYEKEPEKKS----FEENSAG--------APGCPNKWNQYHVCLEFCYDHW--GDGTPEYRLPERYVQNKNRMLAKFPLPENWVEVYDEGLAKYYFWNKTTDEVCWYSPRHPRAIISDPAPRI 135

HSP 2 Score: 63.1586 bits (152), Expect = 4.298e-11
Identity = 31/52 (59.62%), Postives = 33/52 (63.46%), Query Frame = 1 
Query:  847 AYSDAPRGTWKTGLDVRGSAKTGVDSTASGPLFQQRPYPSPGEILRQNALMD 1002
            AY DAP G W  GL V     TG D TA GPLFQQRPYP+PG ILR+    D
Sbjct:  226 AYGDAPVGKWSDGLRV--DQVTGADVTAGGPLFQQRPYPAPGAILRKQKPQD 275
[Close]
BLAST of Polyglutamine-binding protein 1 vs. Ensembl Celegans
Match: pqbp-1.1 (PQBP1 (Polyglutamine tract-binding neurodegeneration protein) homolog [Source:UniProtKB/TrEMBL;Acc:O16786])

HSP 1 Score: 109.383 bits (272), Expect = 2.466e-27
Identity = 59/154 (38.31%), Postives = 88/154 (57.14%), Query Frame = 1 
Query:  148 MSLPPALLARLKKRGINVENKKEMKEEIFAESYDEDNKVQSAINELKDTSIIDVRYIVYEVANCPNLSNPYHKCVEYCIEKYEKKKFNPDLLM----IKKRNTMLKKYPLPPNWIEVADPSTNRFYYWNTKKDEVCWLSPTHPRSIIRLPKDKV 597
            M LPPALLARL+KRGI      + +EE+ AE+Y+++ + +S     ++ S             CPN  N YH C+E+C + +      P+  +    ++ +N ML K+PLP NW+EV D    ++Y+WN   DEVCW SP HPR+II  P  ++
Sbjct:    1 MPLPPALLARLQKRGI-----VKQEEEVIAENYEKEPEKKS----FEENSAG--------APGCPNKWNQYHVCLEFCYDHW--GDGTPEYRLPERYVQNKNRMLAKFPLPENWVEVYDEGLAKYYFWNKTTDEVCWYSPRHPRAIISDPAPRI 135

HSP 2 Score: 63.1586 bits (152), Expect = 4.298e-11
Identity = 31/52 (59.62%), Postives = 33/52 (63.46%), Query Frame = 1 
Query:  847 AYSDAPRGTWKTGLDVRGSAKTGVDSTASGPLFQQRPYPSPGEILRQNALMD 1002
            AY DAP G W  GL V     TG D TA GPLFQQRPYP+PG ILR+    D
Sbjct:  226 AYGDAPVGKWSDGLRV--DQVTGADVTAGGPLFQQRPYPAPGAILRKQKPQD 275
[Close]
BLAST of Polyglutamine-binding protein 1 vs. Ensembl Fly
Match: PQBP1 (gene:FBgn0039270 transcript:FBtr0084765)

HSP 1 Score: 92.4337 bits (228), Expect = 1.581e-21
Identity = 58/169 (34.32%), Postives = 86/169 (50.89%), Query Frame = 1 
Query:  148 MSLPPALLARLKKRGINVENK-----KEMKEEIFAESYDEDNKV--------------QSAINE------LKDTSIIDVRYIVYEVANCPNLSNPYHKCVEYCIEKYEKKKFN-PDLLMIKKRNTMLKKYPLPPNWIEVADPSTNRFYYWNTKKDEVCWLSPTHPRSII 576
            MSLP ALL RLKKRG+  +        E  EEI AE+YD+D+K               + ++ E      +K+   ++  Y  Y++  CPN  N YHKC  YC+ K+     + P    +K+   +L+KYPL   W +V D     FY++N+    V WL P+HP++ I
Sbjct:    1 MSLPAALLQRLKKRGLVTKQSGAAPISEAIEEIIAENYDDDDKSGPYPYKEDTSPEPKRRSVEEKFWSHRIKERIGVNESYHGYKL--CPNKYNIYHKCSLYCVNKFNSSPLSQPSHRYLKRYKRLLRKYPLEAGWKDVYDKGCKAFYFYNSTTQTVSWLPPSHPKARI 167
[Close]
BLAST of Polyglutamine-binding protein 1 vs. Ensembl Zebrafish
Match: pqbp1 (polyglutamine binding protein 1 [Source:ZFIN;Acc:ZDB-GENE-030616-158])

HSP 1 Score: 83.5741 bits (205), Expect = 6.023e-18
Identity = 37/49 (75.51%), Postives = 41/49 (83.67%), Query Frame = 1 
Query:  847 AYSDAPRGTWKTGLDVRGSAKTGVDSTASGPLFQQRPYPSPGEILRQNA 993
            AYSDAPRG+W TGL  R  AKTG D+TA+GPLFQQRPYPSPG +LR NA
Sbjct:  198 AYSDAPRGSWSTGLPKRNEAKTGADTTAAGPLFQQRPYPSPGAVLRANA 246
[Close]
BLAST of Polyglutamine-binding protein 1 vs. Ensembl Zebrafish
Match: pqbp1 (polyglutamine binding protein 1 [Source:ZFIN;Acc:ZDB-GENE-030616-158])

HSP 1 Score: 83.5741 bits (205), Expect = 6.023e-18
Identity = 37/49 (75.51%), Postives = 41/49 (83.67%), Query Frame = 1 
Query:  847 AYSDAPRGTWKTGLDVRGSAKTGVDSTASGPLFQQRPYPSPGEILRQNA 993
            AYSDAPRG+W TGL  R  AKTG D+TA+GPLFQQRPYPSPG +LR NA
Sbjct:  198 AYSDAPRGSWSTGLPKRNEAKTGADTTAAGPLFQQRPYPSPGAVLRANA 246
[Close]
BLAST of Polyglutamine-binding protein 1 vs. Ensembl Mouse
Match: Pqbp1 (polyglutamine binding protein 1 [Source:MGI Symbol;Acc:MGI:1859638])

HSP 1 Score: 85.5001 bits (210), Expect = 1.442e-18
Identity = 37/49 (75.51%), Postives = 41/49 (83.67%), Query Frame = 1 
Query:  847 AYSDAPRGTWKTGLDVRGSAKTGVDSTASGPLFQQRPYPSPGEILRQNA 993
            +YSDAPRGTW TGL  R  AKTG D+TA+GPLFQQRPYPSPG +LR NA
Sbjct:  206 SYSDAPRGTWSTGLPKRNEAKTGADTTAAGPLFQQRPYPSPGAVLRANA 254
[Close]
BLAST of Polyglutamine-binding protein 1 vs. Ensembl Mouse
Match: Pqbp1 (polyglutamine binding protein 1 [Source:MGI Symbol;Acc:MGI:1859638])

HSP 1 Score: 85.5001 bits (210), Expect = 1.442e-18
Identity = 37/49 (75.51%), Postives = 41/49 (83.67%), Query Frame = 1 
Query:  847 AYSDAPRGTWKTGLDVRGSAKTGVDSTASGPLFQQRPYPSPGEILRQNA 993
            +YSDAPRGTW TGL  R  AKTG D+TA+GPLFQQRPYPSPG +LR NA
Sbjct:  206 SYSDAPRGTWSTGLPKRNEAKTGADTTAAGPLFQQRPYPSPGAVLRANA 254
[Close]
BLAST of Polyglutamine-binding protein 1 vs. Ensembl Mouse
Match: Pqbp1 (polyglutamine binding protein 1 [Source:MGI Symbol;Acc:MGI:1859638])

HSP 1 Score: 85.5001 bits (210), Expect = 1.442e-18
Identity = 37/49 (75.51%), Postives = 41/49 (83.67%), Query Frame = 1 
Query:  847 AYSDAPRGTWKTGLDVRGSAKTGVDSTASGPLFQQRPYPSPGEILRQNA 993
            +YSDAPRGTW TGL  R  AKTG D+TA+GPLFQQRPYPSPG +LR NA
Sbjct:  206 SYSDAPRGTWSTGLPKRNEAKTGADTTAAGPLFQQRPYPSPGAVLRANA 254
[Close]
BLAST of Polyglutamine-binding protein 1 vs. Ensembl Mouse
Match: Pqbp1 (polyglutamine binding protein 1 [Source:MGI Symbol;Acc:MGI:1859638])

HSP 1 Score: 51.6026 bits (122), Expect = 3.671e-7
Identity = 22/31 (70.97%), Postives = 25/31 (80.65%), Query Frame = 1 
Query:  847 AYSDAPRGTWKTGLDVRGSAKTGVDSTASGP 939
            +YSDAPRGTW TGL  R  AKTG D+TA+GP
Sbjct:  206 SYSDAPRGTWSTGLPKRNEAKTGADTTAAGP 236
[Close]
BLAST of Polyglutamine-binding protein 1 vs. Ensembl Mouse
Match: Pqbp1 (polyglutamine binding protein 1 [Source:MGI Symbol;Acc:MGI:1859638])

HSP 1 Score: 46.2098 bits (108), Expect = 3.301e-6
Identity = 21/46 (45.65%), Postives = 27/46 (58.70%), Query Frame = 1 
Query:  463 LPPNWIEVADPSTNRFYYWNTKKDEVCWLSPTHPRSIIRLPKDKVK 600
            LPP+W +V DPS    YYWN + D V WLSP  P  ++     KV+
Sbjct:   48 LPPSWYKVFDPSCGLPYYWNVETDLVSWLSPHDPNFVVTKSAKKVR 93
[Close]
BLAST of Polyglutamine-binding protein 1 vs. UniProt/SwissProt
Match: sp|Q91VJ5|PQBP1_MOUSE (Polyglutamine-binding protein 1 OS=Mus musculus OX=10090 GN=Pqbp1 PE=1 SV=1)

HSP 1 Score: 85.5001 bits (210), Expect = 1.009e-17
Identity = 37/49 (75.51%), Postives = 41/49 (83.67%), Query Frame = 1 
Query:  847 AYSDAPRGTWKTGLDVRGSAKTGVDSTASGPLFQQRPYPSPGEILRQNA 993
            +YSDAPRGTW TGL  R  AKTG D+TA+GPLFQQRPYPSPG +LR NA
Sbjct:  206 SYSDAPRGTWSTGLPKRNEAKTGADTTAAGPLFQQRPYPSPGAVLRANA 254
[Close]
BLAST of Polyglutamine-binding protein 1 vs. UniProt/SwissProt
Match: sp|Q6PCT5|PQBP1_RAT (Polyglutamine-binding protein 1 OS=Rattus norvegicus OX=10116 GN=Pqbp1 PE=2 SV=1)

HSP 1 Score: 85.5001 bits (210), Expect = 1.049e-17
Identity = 37/49 (75.51%), Postives = 41/49 (83.67%), Query Frame = 1 
Query:  847 AYSDAPRGTWKTGLDVRGSAKTGVDSTASGPLFQQRPYPSPGEILRQNA 993
            +YSDAPRGTW TGL  R  AKTG D+TA+GPLFQQRPYPSPG +LR NA
Sbjct:  206 SYSDAPRGTWSTGLPKRNEAKTGADTTAAGPLFQQRPYPSPGAVLRANA 254
[Close]
BLAST of Polyglutamine-binding protein 1 vs. UniProt/SwissProt
Match: sp|Q2HJC9|PQBP1_BOVIN (Polyglutamine-binding protein 1 OS=Bos taurus OX=9913 GN=PQBP1 PE=2 SV=1)

HSP 1 Score: 85.1149 bits (209), Expect = 1.422e-17
Identity = 37/49 (75.51%), Postives = 41/49 (83.67%), Query Frame = 1 
Query:  847 AYSDAPRGTWKTGLDVRGSAKTGVDSTASGPLFQQRPYPSPGEILRQNA 993
            +YSDAPRGTW TGL  R  AKTG D+TA+GPLFQQRPYPSPG +LR NA
Sbjct:  206 SYSDAPRGTWSTGLPKRNEAKTGADTTAAGPLFQQRPYPSPGAVLRANA 254
[Close]
BLAST of Polyglutamine-binding protein 1 vs. UniProt/SwissProt
Match: sp|O60828|PQBP1_HUMAN (Polyglutamine-binding protein 1 OS=Homo sapiens OX=9606 GN=PQBP1 PE=1 SV=1)

HSP 1 Score: 84.3445 bits (207), Expect = 2.304e-17
Identity = 37/49 (75.51%), Postives = 41/49 (83.67%), Query Frame = 1 
Query:  847 AYSDAPRGTWKTGLDVRGSAKTGVDSTASGPLFQQRPYPSPGEILRQNA 993
            +YSDAPRGTW TGL  R  AKTG D+TA+GPLFQQRPYPSPG +LR NA
Sbjct:  208 SYSDAPRGTWSTGLPKRNEAKTGADTTAAGPLFQQRPYPSPGAVLRANA 256
[Close]
BLAST of Polyglutamine-binding protein 1 vs. UniProt/SwissProt
Match: sp|A1YFA7|PQBP1_GORGO (Polyglutamine-binding protein 1 OS=Gorilla gorilla gorilla OX=9595 GN=PQBP1 PE=3 SV=1)

HSP 1 Score: 84.3445 bits (207), Expect = 2.304e-17
Identity = 37/49 (75.51%), Postives = 41/49 (83.67%), Query Frame = 1 
Query:  847 AYSDAPRGTWKTGLDVRGSAKTGVDSTASGPLFQQRPYPSPGEILRQNA 993
            +YSDAPRGTW TGL  R  AKTG D+TA+GPLFQQRPYPSPG +LR NA
Sbjct:  208 SYSDAPRGTWSTGLPKRNEAKTGADTTAAGPLFQQRPYPSPGAVLRANA 256
[Close]
BLAST of Polyglutamine-binding protein 1 vs. TrEMBL
Match: A0A183AUF0 (WW domain-containing protein OS=Echinostoma caproni OX=27848 GN=ECPE_LOCUS10585 PE=4 SV=1)

HSP 1 Score: 174.866 bits (442), Expect = 7.758e-48
Identity = 85/165 (51.52%), Postives = 110/165 (66.67%), Query Frame = 1 
Query:  148 MSLPPALLARLKKRGINVENKKEMKEEIFAESYDEDNK-VQSAINELKDTSIIDVRY------------IVYEVANCPNLSNPYHKCVEYCIEKYEKKKFNPDLLMIKKRNTMLKKYPLPPNWIEVADPSTNRFYYWNTKKDEVCWLSPTHPRSIIRLPKDKVKA 603
            M LPPALLARLKKRG+     K  K+E+FAE+YDE+++  Q     L++   ID  +            ++YE A CPNL NPYH CV YC E+Y ++KF  DL  ++ +N ML++YPLP +W+EV DPST RFYYWNTK D+VCWLSP HPR+ I  P D V+A
Sbjct:    1 MPLPPALLARLKKRGL----VKAEKKEVFAENYDEESEPAQETAIHLENPIAIDNTHTISPLPIIENGILIYECAQCPNLQNPYHNCVAYCFERYGRRKFFSDLRNMRLKNRMLQRYPLPSHWLEVGDPSTGRFYYWNTKTDDVCWLSPLHPRAKISQPGDIVRA 161

HSP 2 Score: 67.3958 bits (163), Expect = 9.615e-9
Identity = 31/51 (60.78%), Postives = 38/51 (74.51%), Query Frame = 1 
Query:  865 RGTWKTGLDVRG---SAKTGVDSTASGPLFQQRPYPSPGEILRQNALMDGK 1008
            +GTW  GL+V+    +AKTGVD TASG L+QQRPYPSPG+ILR NA    +
Sbjct:  276 KGTWSAGLEVKSTMPAAKTGVDETASGSLYQQRPYPSPGDILRANAAAQAR 326
[Close]
BLAST of Polyglutamine-binding protein 1 vs. TrEMBL
Match: A0A0R3W9C5 (WW domain-containing protein OS=Taenia asiatica OX=60517 GN=TASK_LOCUS7040 PE=4 SV=1)

HSP 1 Score: 167.548 bits (423), Expect = 2.918e-45
Identity = 79/157 (50.32%), Postives = 105/157 (66.88%), Query Frame = 1 
Query:  148 MSLPPALLARLKKRGINVENKKEMKEEIFAESYDEDNK--VQSAINELKDTSIIDVRYIVYEVANCPNLSNPYHKCVEYCIEKYEKKKFNP-DLLMIKKRNTMLKKYPLPPNWIEVADPSTNRFYYWNTKKDEVCWLSPTHPRSIIRLPKDKVKALT 609
            M LPPAL ARL KRG+  ++K E  EE+FAESYD D    +  A+  +    II+   +++E+A CPNL+NPYH+C  YC E+Y ++ F   D  M + R+ ML++YPLP +W+EV DP T RFYYWNT  DEVCWLSP HPR+I+      +KA T
Sbjct:    1 MPLPPALAARLAKRGLLDKSKNE--EEVFAESYDNDGSGPIPPALKGISPVPIIENGTLIHEIAACPNLTNPYHECTAYCFERYGRRTFRASDQRMGRLRDRMLRRYPLPSHWLEVGDPVTGRFYYWNTVTDEVCWLSPLHPRAIVTKSASVLKAQT 155

HSP 2 Score: 73.559 bits (179), Expect = 6.904e-11
Identity = 37/52 (71.15%), Postives = 40/52 (76.92%), Query Frame = 1 
Query:  847 AYSDAPRGTWKTGLD-VRGSA---KTGVDSTASGPLFQQRPYPSPGEILRQN 990
            AYSD PRG W  GL+ V GSA   KTG D TASGPLFQQRPYPSPG++LR N
Sbjct:  257 AYSDVPRGGWTAGLEGVSGSAPSAKTGADVTASGPLFQQRPYPSPGDVLRAN 308
[Close]
BLAST of Polyglutamine-binding protein 1 vs. TrEMBL
Match: A0A068Y6Q4 (Polyglutamine binding protein 1 OS=Echinococcus multilocularis OX=6211 GN=EmuJ_000523900 PE=4 SV=1)

HSP 1 Score: 167.162 bits (422), Expect = 4.097e-45
Identity = 80/157 (50.96%), Postives = 104/157 (66.24%), Query Frame = 1 
Query:  148 MSLPPALLARLKKRGINVENKKEMKEEIFAESYDEDNKVQ--SAINELKDTSIIDVRYIVYEVANCPNLSNPYHKCVEYCIEKYEKKKFNP-DLLMIKKRNTMLKKYPLPPNWIEVADPSTNRFYYWNTKKDEVCWLSPTHPRSIIRLPKDKVKALT 609
            M LPPAL ARL KRG+  ++K E  EE+FAESYD D   Q    +  +    II+   +++E+A CPNL+NPYH+C  YC E+Y ++ F   D  M + R+ ML++YPLP +W+EV DP T RFYYWNT  DEVCWLSP HPR+II      +KA T
Sbjct:    1 MPLPPALAARLAKRGLLDKSKNE--EEVFAESYDGDGSGQIPPILKGISPVPIIENGTLIHEIAACPNLTNPYHECTAYCFERYGRRTFRASDQHMGRLRDRMLRRYPLPSHWLEVGDPVTGRFYYWNTVTDEVCWLSPLHPRAIITKSASVLKAQT 155

HSP 2 Score: 73.9442 bits (180), Expect = 6.111e-11
Identity = 37/52 (71.15%), Postives = 40/52 (76.92%), Query Frame = 1 
Query:  847 AYSDAPRGTWKTGLD-VRGSA---KTGVDSTASGPLFQQRPYPSPGEILRQN 990
            AYSD PRG W  GL+ V GSA   KTG D TASGPLFQQRPYPSPG++LR N
Sbjct:  257 AYSDVPRGGWTAGLEGVSGSAPSAKTGADVTASGPLFQQRPYPSPGDVLRAN 308
[Close]
BLAST of Polyglutamine-binding protein 1 vs. TrEMBL
Match: U6J9Y9 (Polyglutamine binding protein 1 OS=Echinococcus granulosus OX=6210 GN=EGR_03867 PE=4 SV=1)

HSP 1 Score: 167.162 bits (422), Expect = 4.274e-45
Identity = 80/157 (50.96%), Postives = 104/157 (66.24%), Query Frame = 1 
Query:  148 MSLPPALLARLKKRGINVENKKEMKEEIFAESYDEDNKVQ--SAINELKDTSIIDVRYIVYEVANCPNLSNPYHKCVEYCIEKYEKKKFNP-DLLMIKKRNTMLKKYPLPPNWIEVADPSTNRFYYWNTKKDEVCWLSPTHPRSIIRLPKDKVKALT 609
            M LPPAL ARL KRG+  ++K E  EE+FAESYD D   Q    +  +    II+   +++E+A CPNL+NPYH+C  YC E+Y ++ F   D  M + R+ ML++YPLP +W+EV DP T RFYYWNT  DEVCWLSP HPR+II      +KA T
Sbjct:    1 MPLPPALAARLAKRGLLDKSKNE--EEVFAESYDGDGSGQIPPILKGISPVPIIENGTLIHEIAACPNLTNPYHECTAYCFERYGRRTFRASDQHMGRLRDRMLRRYPLPSHWLEVGDPVTGRFYYWNTVTDEVCWLSPLHPRAIITKSASVLKAQT 155

HSP 2 Score: 73.559 bits (179), Expect = 6.588e-11
Identity = 37/52 (71.15%), Postives = 40/52 (76.92%), Query Frame = 1 
Query:  847 AYSDAPRGTWKTGLD-VRGSA---KTGVDSTASGPLFQQRPYPSPGEILRQN 990
            AYSD PRG W  GL+ V GSA   KTG D TASGPLFQQRPYPSPG++LR N
Sbjct:  257 AYSDVPRGGWTAGLEGVSGSAPSAKTGADVTASGPLFQQRPYPSPGDVLRAN 308
[Close]
BLAST of Polyglutamine-binding protein 1 vs. TrEMBL
Match: Q5BW59 (SJCHGC04923 protein (Fragment) OS=Schistosoma japonicum OX=6182 PE=2 SV=2)

HSP 1 Score: 164.466 bits (415), Expect = 4.664e-45
Identity = 81/163 (49.69%), Postives = 105/163 (64.42%), Query Frame = 1 
Query:  148 MSLPPALLARLKKRGINVENKKEMKEEIFAESYDEDNKVQSAIN-----------ELKDTSIIDVRYIVYEVANCPNLSNPYHKCVEYCIEKYEKKKFNPDLLMIKKRNTMLKKYPLPPNWIEVADPSTNRFYYWNTKKDEVCWLSPTHPRSIIRLPKDKVKA 603
            M LPPALLARLKKRGI     +E  EE+FAE+YDE+++    I             +    II+   +++E A CPN +NPYH C  YC E+Y ++KFN D   I  ++ ML++YPLP +WIEV DP T RFYYWNTK D+VCWLSP HPR+ I  P + V+A
Sbjct:    1 MPLPPALLARLKKRGIVSTGPQEEVEEVFAENYDEESEPVLPITFDQPFNVKKCYTVSPVPIIENGVLIHECAECPNQTNPYHICSPYCYERYGRRKFNADPTSIHLKSRMLRRYPLPSHWIEVGDPVTGRFYYWNTKTDDVCWLSPLHPRAKISQPGNIVRA 163
[Close]
BLAST of Polyglutamine-binding protein 1 vs. Ensembl Cavefish
Match: pqbp1 (polyglutamine binding protein 1 [Source:NCBI gene;Acc:103024004])

HSP 1 Score: 84.3445 bits (207), Expect = 2.364e-18
Identity = 37/51 (72.55%), Postives = 42/51 (82.35%), Query Frame = 1 
Query:  847 AYSDAPRGTWKTGLDVRGSAKTGVDSTASGPLFQQRPYPSPGEILRQNALM 999
            AYSDAPRG+W TGL  R  AKTG D+TA+GPLFQQRPYPSPG +LR NA +
Sbjct:  187 AYSDAPRGSWSTGLPKRNEAKTGADTTAAGPLFQQRPYPSPGAVLRANAEL 237

HSP 2 Score: 63.5438 bits (153), Expect = 3.491e-11
Identity = 44/143 (30.77%), Postives = 57/143 (39.86%), Query Frame = 1 
Query:  148 MSLPPALLARLKKRGINVENKKEMKEEIFAESYDEDNKVQSAINELKDTSIIDVRYIVYEVANCPNLSNPYHKCVEYCIEKYEKKKFNPDLLMIKKRNTMLKKYPLPPNWIEVADPSTNRFYYWNTKKDEVCWLSPTHPRSII 576
            M LPPALLARL KRGI  +++ + +EEI AE YD++N                   + YE     NL                                       P NW +V DP+    YYWN + D V WLSP  P ++I
Sbjct:    1 MPLPPALLARLAKRGILKQSEHDNEEEIIAEDYDDNN-------------------VDYEATRVENL---------------------------------------PTNWYKVLDPTCGLPYYWNVETDLVSWLSPNDPAALI 85
[Close]
BLAST of Polyglutamine-binding protein 1 vs. Ensembl Cavefish
Match: pqbp1 (polyglutamine binding protein 1 [Source:NCBI gene;Acc:103024004])

HSP 1 Score: 70.8626 bits (172), Expect = 9.239e-14
Identity = 30/42 (71.43%), Postives = 34/42 (80.95%), Query Frame = 1 
Query:  865 RGTWKTGLDVRGSAKTGVDSTASGPLFQQRPYPSPGEILRQN 990
            RG+W TGL  R  AKTG D+TA+GPLFQQRPYPSPG +LR N
Sbjct:  191 RGSWSTGLPKRNEAKTGADTTAAGPLFQQRPYPSPGAVLRAN 232

HSP 2 Score: 61.2326 bits (147), Expect = 1.836e-10
Identity = 44/143 (30.77%), Postives = 57/143 (39.86%), Query Frame = 1 
Query:  148 MSLPPALLARLKKRGINVENKKEMKEEIFAESYDEDNKVQSAINELKDTSIIDVRYIVYEVANCPNLSNPYHKCVEYCIEKYEKKKFNPDLLMIKKRNTMLKKYPLPPNWIEVADPSTNRFYYWNTKKDEVCWLSPTHPRSII 576
            M LPPALLARL KRGI  +++ + +EEI AE YD++                +V Y    V N                                          LP NW +V DP+    YYWN + D V WLSP  P ++I
Sbjct:    1 MPLPPALLARLAKRGILKQSEHDNEEEIIAEDYDDN----------------NVDYEATRVEN------------------------------------------LPTNWYKVLDPTCGLPYYWNVETDLVSWLSPNDPAALI 85
[Close]
BLAST of Polyglutamine-binding protein 1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000010613.1 (pep scaffold:Pmarinus_7.0:GL477304:49154:64850:1 gene:ENSPMAG00000009610.1 transcript:ENSPMAT00000010613.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 86.6557 bits (213), Expect = 8.766e-20
Identity = 37/49 (75.51%), Postives = 40/49 (81.63%), Query Frame = 1 
Query:  847 AYSDAPRGTWKTGLDVRGSAKTGVDSTASGPLFQQRPYPSPGEILRQNA 993
            AYSDAPRG W  GL  +G AKTG D+TASGPLFQQRPYPSPG +LR NA
Sbjct:  212 AYSDAPRGNWSAGLQRKGDAKTGADTTASGPLFQQRPYPSPGAVLRANA 260

HSP 2 Score: 52.373 bits (124), Expect = 4.687e-8
Identity = 44/152 (28.95%), Postives = 52/152 (34.21%), Query Frame = 1 
Query:  148 MSLPPALLARLKKRGINVENKKEMKEEIFAESYDEDNKVQSAINELKDTSIIDVRYIVYEVANCPNLSNPYHKCVEYCIEKYEKKKFNPDLLMIKKRNTMLKKYPLPPNWIEVADPSTNRFYYWNTKKDEVCWLSPTHPRSIIRLPKDKVKA 603
            M LPPAL ARL KRG+      E  EEI AE Y                   D   I YE     NL                                       P NW +V DP +   YYWN + D V WL+P  P ++I     K+ A
Sbjct:    1 MPLPPALQARLAKRGLLKNVLSEADEEIIAEDY-------------------DENEIDYESTKNENL---------------------------------------PLNWYKVVDPDSRLPYYWNAETDMVSWLAPADPLAVITKAAKKIPA 94
[Close]
BLAST of Polyglutamine-binding protein 1 vs. Ensembl Nematostella
Match: EDO31798 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SWW0])

HSP 1 Score: 87.4261 bits (215), Expect = 5.157e-20
Identity = 53/149 (35.57%), Postives = 70/149 (46.98%), Query Frame = 1 
Query:  148 MSLPPALLARLKKRGINVENKKEMKEEIFAESYDEDNKVQSAINELKDTSIIDVRYIVYEVANCPNLSNPYHKCVEYCIEKYEKKKFNPDLLMIKKRNTMLKKY---PLPPNWIEVADPSTNRFYYWNTKKDEVCWLSPTHPRSIIRLP 585
            M LP AL ARL KRGI                     K +S+  E  D+S         +   CPN +NPYH+C EYC ++Y +   +        +   +K Y   PLPPNW  + DP+  R YYWNT  ++V WL P  P + I LP
Sbjct:    1 MPLPAALQARLMKRGIVP-------------------KGESSKEEKTDSS--------GQCKGCPNTTNPYHECSEYCHKRYGRGAVD------HTQAPHIKDYSHVPLPPNWYFIPDPAGGRHYYWNTSTNQVSWLHPMDPAAEITLP 116

HSP 2 Score: 81.2629 bits (199), Expect = 9.645e-18
Identity = 36/48 (75.00%), Postives = 40/48 (83.33%), Query Frame = 1 
Query:  847 AYSDAPRGTWKTGLDVRGSAKTGVDSTASGPLFQQRPYPSPGEILRQN 990
            +YSDAPRG W +GL  +G AKTGVD TA+GPLFQQRPYPSPG ILR N
Sbjct:  193 SYSDAPRGDWSSGLHQKGDAKTGVDVTANGPLFQQRPYPSPGAILRAN 240
[Close]
BLAST of Polyglutamine-binding protein 1 vs. Ensembl Medaka
Match: pqbp1 (polyglutamine binding protein 1 [Source:NCBI gene;Acc:101167869])

HSP 1 Score: 82.4185 bits (202), Expect = 6.247e-18
Identity = 36/49 (73.47%), Postives = 41/49 (83.67%), Query Frame = 1 
Query:  847 AYSDAPRGTWKTGLDVRGSAKTGVDSTASGPLFQQRPYPSPGEILRQNA 993
            AYSDAPRG+W +GL  R  AKTG D+TA+GPLFQQRPYPSPG +LR NA
Sbjct:  172 AYSDAPRGSWSSGLPKRNEAKTGADTTAAGPLFQQRPYPSPGAVLRANA 220

HSP 2 Score: 50.0618 bits (118), Expect = 8.476e-7
Identity = 45/143 (31.47%), Postives = 57/143 (39.86%), Query Frame = 1 
Query:  148 MSLPPALLARLKKRGINVENKKEMKEEIFAESYDEDNKVQSAINELKDTSIIDVRYIVYEVANCPNLSNPYHKCVEYCIEKYEKKKFNPDLLMIKKRNTMLKKYPLPPNWIEVADPSTNRFYYWNTKKDEVCWLSPTHPRSII 576
            M LPPALLARL KRGI   + +E++EEI AE YD++N                   + YE     NL                                       PPNW +V D +    YYWN + D V WLSP  P ++I
Sbjct:    1 MPLPPALLARLAKRGIVKPSDQEIEEEIIAEDYDDNN-------------------VDYEATRLENL---------------------------------------PPNWYKVFDSTCGLPYYWNIESDLVSWLSPNDPSAVI 85
[Close]
BLAST of Polyglutamine-binding protein 1 vs. Planmine SMEST
Match: SMESG000040247.1 (SMESG000040247.1)

HSP 1 Score: 432.95 bits (1112), Expect = 6.755e-153
Identity = 299/301 (99.34%), Postives = 299/301 (99.34%), Query Frame = 1 
Query:  148 MSLPPALLARLKKRGINVENKKEMKEEIFAESYDEDNKVQSAINELKDTSIIDVRYIVYEVANCPNLSNPYHKCVEYCIEKYEKKKFNPDLLMIKKRNTMLKKYPLPPNWIEVADPSTNRFYYWNTKKDEVCWLSPTHPRSIIRLPKDKVKALTKPSERIKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXAYSDAPRGTWKTGLDVRGSAKTGVDSTASGPLFQQRPYPSPGEILRQNALMDGKKSXXXXXXXXXXRK 1050
            MSLPPALLARLKKRGINVENKKEMKEEIFAESYDEDNKVQSAINELKDTSIIDVRYIVYEVANCPNLSNPYHKCVEYCIEKYEKKKFNPDLLMIKKRNTMLKKYPLPPNWIEVADPSTNRFYYWNTKKDEVCWLSPTHPRSIIRLPKDKVKALTKPSERIKESRRERDYSRERRRRRRSSSDSRSSSSNRSRSSDSADERRSSRHKSRKEKSDKRKEDKKKLDDPSLDPMDPSAYSDAPRGTWKTGLDVRGSAKTGVDSTASGPLFQQRPYPSPGEILRQNALMDGKKSEDE DDD DDRK
Sbjct:    1 MSLPPALLARLKKRGINVENKKEMKEEIFAESYDEDNKVQSAINELKDTSIIDVRYIVYEVANCPNLSNPYHKCVEYCIEKYEKKKFNPDLLMIKKRNTMLKKYPLPPNWIEVADPSTNRFYYWNTKKDEVCWLSPTHPRSIIRLPKDKVKALTKPSERIKESRRERDYSRERRRRRRSSSDSRSSSSNRSRSSDSADERRSSRHKSRKEKSDKRKEDKKKLDDPSLDPMDPSAYSDAPRGTWKTGLDVRGSAKTGVDSTASGPLFQQRPYPSPGEILRQNALMDGKKSEDEDDDDDDDRK 301
The following BLAST results are available for this feature:
BLAST of Polyglutamine-binding protein 1 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
PQBP18.386e-1975.51polyglutamine binding protein 1 [Source:HGNC Symbo... [more]
PQBP11.403e-1875.51polyglutamine binding protein 1 [Source:HGNC Symbo... [more]
PQBP11.403e-1875.51polyglutamine binding protein 1 [Source:HGNC Symbo... [more]
PQBP14.797e-1875.51polyglutamine binding protein 1 [Source:HGNC Symbo... [more]
PQBP14.797e-1875.51polyglutamine binding protein 1 [Source:HGNC Symbo... [more]
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BLAST of Polyglutamine-binding protein 1 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 2
Match NameE-valueIdentityDescription
pqbp-1.12.466e-2738.31PQBP1 (Polyglutamine tract-binding neurodegenerati... [more]
pqbp-1.12.466e-2738.31PQBP1 (Polyglutamine tract-binding neurodegenerati... [more]
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BLAST of Polyglutamine-binding protein 1 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 1
Match NameE-valueIdentityDescription
PQBP11.581e-2134.32gene:FBgn0039270 transcript:FBtr0084765[more]
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BLAST of Polyglutamine-binding protein 1 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 2
Match NameE-valueIdentityDescription
pqbp16.023e-1875.51polyglutamine binding protein 1 [Source:ZFIN;Acc:Z... [more]
pqbp16.023e-1875.51polyglutamine binding protein 1 [Source:ZFIN;Acc:Z... [more]
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BLAST of Polyglutamine-binding protein 1 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Polyglutamine-binding protein 1 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Pqbp11.442e-1875.51polyglutamine binding protein 1 [Source:MGI Symbol... [more]
Pqbp11.442e-1875.51polyglutamine binding protein 1 [Source:MGI Symbol... [more]
Pqbp11.442e-1875.51polyglutamine binding protein 1 [Source:MGI Symbol... [more]
Pqbp13.671e-770.97polyglutamine binding protein 1 [Source:MGI Symbol... [more]
Pqbp13.301e-645.65polyglutamine binding protein 1 [Source:MGI Symbol... [more]
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BLAST of Polyglutamine-binding protein 1 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q91VJ5|PQBP1_MOUSE1.009e-1775.51Polyglutamine-binding protein 1 OS=Mus musculus OX... [more]
sp|Q6PCT5|PQBP1_RAT1.049e-1775.51Polyglutamine-binding protein 1 OS=Rattus norvegic... [more]
sp|Q2HJC9|PQBP1_BOVIN1.422e-1775.51Polyglutamine-binding protein 1 OS=Bos taurus OX=9... [more]
sp|O60828|PQBP1_HUMAN2.304e-1775.51Polyglutamine-binding protein 1 OS=Homo sapiens OX... [more]
sp|A1YFA7|PQBP1_GORGO2.304e-1775.51Polyglutamine-binding protein 1 OS=Gorilla gorilla... [more]
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BLAST of Polyglutamine-binding protein 1 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A183AUF07.758e-4851.52WW domain-containing protein OS=Echinostoma capron... [more]
A0A0R3W9C52.918e-4550.32WW domain-containing protein OS=Taenia asiatica OX... [more]
A0A068Y6Q44.097e-4550.96Polyglutamine binding protein 1 OS=Echinococcus mu... [more]
U6J9Y94.274e-4550.96Polyglutamine binding protein 1 OS=Echinococcus gr... [more]
Q5BW594.664e-4549.69SJCHGC04923 protein (Fragment) OS=Schistosoma japo... [more]
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BLAST of Polyglutamine-binding protein 1 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 2
Match NameE-valueIdentityDescription
pqbp12.364e-1872.55polyglutamine binding protein 1 [Source:NCBI gene;... [more]
pqbp19.239e-1471.43polyglutamine binding protein 1 [Source:NCBI gene;... [more]
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BLAST of Polyglutamine-binding protein 1 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 1
Match NameE-valueIdentityDescription
ENSPMAT00000010613.18.766e-2075.51pep scaffold:Pmarinus_7.0:GL477304:49154:64850:1 g... [more]
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BLAST of Polyglutamine-binding protein 1 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Polyglutamine-binding protein 1 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 1
Match NameE-valueIdentityDescription
EDO317985.157e-2035.57Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Polyglutamine-binding protein 1 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 1
Match NameE-valueIdentityDescription
pqbp16.247e-1873.47polyglutamine binding protein 1 [Source:NCBI gene;... [more]
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BLAST of Polyglutamine-binding protein 1 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 1
Match NameE-valueIdentityDescription
SMESG000040247.16.755e-15399.34SMESG000040247.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30028254 ID=SMED30028254|Name=Polyglutamine-binding protein 1|organism=Schmidtea mediterranea sexual|type=transcript|length=1106bp
TTAACATTGTTGCACTTATAAAATCTTTTTTTTAAGATACACCATATCTA
TTTTTGTCTAATATTTCTGATAAATTTCATTAGTTAATTCTAAATTTTTT
TTTCTTTTAAAAAGTTTACAATCAACTATATTTTTATTATTACAAAAATG
AGTTTGCCACCAGCTTTATTGGCTCGTTTAAAGAAAAGGGGCATTAATGT
GGAAAATAAAAAAGAAATGAAAGAGGAAATATTTGCTGAAAGTTACGATG
AAGATAATAAAGTACAATCAGCCATTAACGAATTAAAGGATACATCTATT
ATTGATGTTCGATATATAGTCTATGAAGTTGCTAATTGTCCTAATTTATC
AAATCCATATCATAAATGTGTTGAATATTGCATTGAAAAATATGAAAAAA
AGAAGTTTAATCCAGATTTGTTAATGATTAAGAAAAGAAATACAATGCTT
AAAAAATATCCCCTGCCCCCTAATTGGATTGAAGTTGCCGATCCATCTAC
AAATCGATTTTATTATTGGAATACAAAAAAAGATGAAGTTTGCTGGTTAT
CACCAACACACCCGCGTTCAATTATAAGACTACCCAAAGATAAAGTGAAA
GCTTTAACAAAACCTTCTGAGCGTATTAAAGAGAGTAGACGAGAGAGAGA
CTATTCAAGAGAACGCAGGCGAAGGAGACGCTCTTCGTCAGATTCAAGAT
CAAGCTCATCTAATCGTAGTAGAAGTAGCGATAGTGCCGATGAAAGGCGT
TCGAGTAGACATAAATCTCGGAAAGAAAAATCAGACAAACGCAAAGAAGA
TAAAAAAAAATTGGATGATCCCTCACTCGACCCAATGGACCCTTCTGCAT
ATTCAGATGCTCCGAGAGGGACTTGGAAAACTGGACTTGATGTTCGTGGG
TCTGCCAAAACCGGAGTAGATTCGACAGCATCGGGTCCATTGTTTCAACA
ACGTCCATATCCAAGTCCAGGGGAAATTTTACGACAAAATGCTCTTATGG
ATGGGAAGAAATCTGAAGATGAATATGACGATGATCATGACGATAGAAAA
TGATCTTTTTCTTGTGTTTTGAAAATAAATTTGTTTTGATTGAAAAAAAA
AGATCG
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protein sequence of SMED30028254-orf-1

>SMED30028254-orf-1 ID=SMED30028254-orf-1|Name=SMED30028254-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=302bp
MSLPPALLARLKKRGINVENKKEMKEEIFAESYDEDNKVQSAINELKDTS
IIDVRYIVYEVANCPNLSNPYHKCVEYCIEKYEKKKFNPDLLMIKKRNTM
LKKYPLPPNWIEVADPSTNRFYYWNTKKDEVCWLSPTHPRSIIRLPKDKV
KALTKPSERIKESRRERDYSRERRRRRRSSSDSRSSSSNRSRSSDSADER
RSSRHKSRKEKSDKRKEDKKKLDDPSLDPMDPSAYSDAPRGTWKTGLDVR
GSAKTGVDSTASGPLFQQRPYPSPGEILRQNALMDGKKSEDEYDDDHDDR
K*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: biological process
TermDefinition
GO:0002218activation of innate immune response
GO:0002230positive regulation of defense response to virus by host
GO:0002376immune system process
GO:0032481positive regulation of type I interferon production
GO:0045087innate immune response
GO:0051607defense response to virus
GO:0071360cellular response to exogenous dsRNA
GO:0006355regulation of transcription, DNA-templated
GO:0000380alternative mRNA splicing, via spliceosome
GO:0006351transcription, DNA-templated
GO:0006397mRNA processing
GO:0008380RNA splicing
GO:0031175neuron projection development
GO:1902857positive regulation of non-motile cilium assembly
Vocabulary: molecular function
TermDefinition
GO:0003690double-stranded DNA binding
GO:0008270zinc ion binding
GO:0005515protein binding
GO:0008022protein C-terminus binding
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000020protonephridia
Vocabulary: INTERPRO
TermDefinition
IPR036249Thioredoxin-like_sf
IPR036020WW_dom_sf
IPR013088Znf_NHR/GATA
IPR001202WW_dom
Vocabulary: cellular component
TermDefinition
GO:0005634nucleus
GO:0005813centrosome
GO:0005929cilium
GO:0016607nuclear speck
GO:0097546ciliary base
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR001202WW domainSMARTSM00456ww_5coord: 105..138
e-value: 1.3E-5
score: 34.7
IPR001202WW domainPFAMPF00397WWcoord: 106..134
e-value: 4.1E-7
score: 30.0
IPR001202WW domainPROSITEPS50020WW_DOMAIN_2coord: 104..138
score: 11.822
IPR001202WW domainCDDcd00201WWcoord: 107..137
e-value: 0.00830438
score: 31.3442
NoneNo IPR availableGENE3DG3DSA:2.20.70.10coord: 102..158
e-value: 1.5E-8
score: 36.1
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 193..227
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 146..301
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 146..183
NoneNo IPR availablePANTHERPTHR21737POLYGLUTAMINE BINDING PROTEIN 1/MARVEL MEMBRANE-ASSOCIATING DOMAIN CONTAINING 3coord: 162..291
coord: 1..149
NoneNo IPR availablePANTHERPTHR21737:SF3POLYGLUTAMINE-BINDING PROTEIN 1coord: 1..149
coord: 162..291
IPR036249Thioredoxin-like superfamilyGENE3DG3DSA:3.40.30.10coord: 200..291
e-value: 5.0E-24
score: 87.1
IPR036020WW domain superfamilySUPERFAMILYSSF51045WW domaincoord: 98..140