Serine palmitoyltransferase 2

Overview
NameSerine palmitoyltransferase 2
Smed IDSMED30028172
Length (bp)1844
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Serine palmitoyltransferase 2 (SMED30028172) t-SNE clustered cells

Violin plots show distribution of expression levels for Serine palmitoyltransferase 2 (SMED30028172) in cells (dots) of each of the 12 neoblast clusters.

 

back to top

 

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Serine palmitoyltransferase 2 (SMED30028172) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Serine palmitoyltransferase 2 (SMED30028172) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

back to top

 

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

back to top
Anatomical Expression

PAGE et. al., 2020



SMED30028172

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 11

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
intestinal phagocyteSMED30028172h1SMcG0003818 Contig3749GPL15192PMID:23079596
Forsthoefel et al., 2012		FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
intestinal phagocyteSMED30028172h1SMcG0003818 Contig2958GPL15192PMID:23079596
Forsthoefel et al., 2012		FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
pharynxSMED30028172h1SMcG0003818 dd_Smed_v4_1633_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
nervous systemSMED30028172h1SMcG0003818 dd_Smed_v4_1633_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
gutSMED30028172h1SMcG0003818 dd_Smed_v4_1633_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
epidermisSMED30028172h1SMcG0003818 dd_Smed_v4_1633_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30028172h1SMcG0003818 dd_Smed_v4_1633_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymaSMED30028172h1SMcG0003818 dd_Smed_v4_1633_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30028172h1SMcG0003818 Contig46182uc_Smed_v2PMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30028172h1SMcG0003818 Contig46182newmark_estsPMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
epidermisSMED30028172h1SMcG0003818 dd_Smed_v4_1633_0_1dd_Smed_v4PMID:28292427
Wurtzel et al., 2017		whole organism asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Serine palmitoyltransferase 2 vs. Ensembl Human
Match: SPTLC2 (serine palmitoyltransferase long chain base subunit 2 [Source:HGNC Symbol;Acc:HGNC:11278])

HSP 1 Score: 536.184 bits (1380), Expect = 0.000e+0
Identity = 261/499 (52.30%), Postives = 347/499 (69.54%), Query Frame = 1 
Query:   40 GHIKSIKQETKCKESEFFEQFEKASLFNSLITYLYFFILKCMGKLRDFMRNYGLEKNRLAVDSTKNKGFAPLYLDFEAFYTRNVYRRVCDCVNKPICSAPGGSLKAMNRVSDDHNWTFRILDST-SDIYNFGSYNYLGFAQNDGLCTDYVEKSINEFGLSVGSPRQEVGNTLYHLELEESLAEFLGQEAAIVFPMGFATNALNIPILVDKDCCVISDELNHVSLILGIRLSGADTRRFKHNNVESLERELIKAITEGHSKTKRKFKKILVVVEGVYSMEGSIVRLPEILELKKKYKFYIYLDEAHSIGALGKGGRGVVDYFNLNPHEVDIQMGTFTKSFASSGGYISGSRNLIHYVREKSHSTIYGGTMSGPICQQILSAMAIIGGKMGGSLGAERIRQLAWNTTYFRAALHRMGLIVFGNKNSPVIPVIVYTIPKVVAFHRECMRRGIGTVIVGYPACNLKLARIRFCISAAHTKRSLDYTLSIVDEIATHLRFKYSR 1533
            G I  + Q     +  F E FE+  +  +++TY+ + +L   G LRDF+R + +EK   A +  + K F  LY DFE FYTRN+Y R+ D  N+PICS PG  +  M R S D+NW+F+   +    + N GSYNYLGFA+N G C +   K + E+G  V S RQE+GN   H ELEE +A FLG EAA+ + MGFATN++NIP LV K C ++SDELNH SL+LG RLSGA  R FKHNN++SLE+ L  AI  G  +T+R +KKIL++VEG+YSMEGSIVRLPE++ LKKKYK Y+YLDEAHSIGALG  GRGVV+YF L+P +VD+ MGTFTKSF +SGGYI G + LI Y+R  SHS +Y  ++S P+ +QI+++M  I G+ G SLG E ++QLA NT YFR  L  MG I++GN++SPV+P+++Y   K+ AF RE ++R IG V+VG+PA  +  +R RFC+SAAHTK  LD  L  +DE+   L+ KYSR
Sbjct:   43 GQIHHVTQNGGLYKRPFNEAFEETPMLVAVLTYVGYGVLTLFGYLRDFLRYWRIEKCHHATEREEQKDFVSLYQDFENFYTRNLYMRIRDNWNRPICSVPGARVDIMERQSHDYNWSFKYTGNIIKGVINMGSYNYLGFARNTGSCQEAAAKVLEEYGAGVCSTRQEIGNLDKHEELEELVARFLGVEAAMAYGMGFATNSMNIPALVGKGCLILSDELNHASLVLGARLSGATIRIFKHNNMQSLEKLLKDAIVYGQPRTRRPWKKILILVEGIYSMEGSIVRLPEVIALKKKYKAYLYLDEAHSIGALGPTGRGVVEYFGLDPEDVDVMMGTFTKSFGASGGYIGGKKELIDYLRTHSHSAVYATSLSPPVVEQIITSMKCIMGQDGTSLGKECVQQLAENTRYFRRRLKEMGFIIYGNEDSPVVPLMLYMPAKIGAFGREMLKRNIGVVVVGFPATPIIESRARFCLSAAHTKEILDTALKEIDEVGDLLQLKYSR 541
[Close]
BLAST of Serine palmitoyltransferase 2 vs. Ensembl Human
Match: SPTLC3 (serine palmitoyltransferase long chain base subunit 3 [Source:HGNC Symbol;Acc:HGNC:16253])

HSP 1 Score: 526.554 bits (1355), Expect = 0.000e+0
Identity = 259/502 (51.59%), Postives = 342/502 (68.13%), Query Frame = 1 
Query:   37 NGHIKSIKQETKCK--ESEFFEQFEKASLFNSLITYLYFFILKCMGKLRDFMRNYGLEKNRLAVDSTKNKGFAPLYLDFEAFYTRNVYRRVCDCVNKPICSAPGGSLKAMNRVSDDHNWTFRILDST-SDIYNFGSYNYLGFAQNDGLCTDYVEKSINEFGLSVGSPRQEVGNTLYHLELEESLAEFLGQEAAIVFPMGFATNALNIPILVDKDCCVISDELNHVSLILGIRLSGADTRRFKHNNVESLERELIKAITEGHSKTKRKFKKILVVVEGVYSMEGSIVRLPEILELKKKYKFYIYLDEAHSIGALGKGGRGVVDYFNLNPHEVDIQMGTFTKSFASSGGYISGSRNLIHYVREKSHSTIYGGTMSGPICQQILSAMAIIGGKMGGSLGAERIRQLAWNTTYFRAALHRMGLIVFGNKNSPVIPVIVYTIPKVVAFHRECMRRGIGTVIVGYPACNLKLARIRFCISAAHTKRSLDYTLSIVDEIATHLRFKYSR 1533
            NG +K  +Q  K    +    E FE+A L   + TY+ + I    G LRDF+RN+G+EK   AV+  + K F PLY DFE FYTRN+Y R+ D  N+PICSAPG     M RVSDD+NWTFR       D+ N GSYN+LG A         ++  +  +G  V S R E+G    H ELE+ +A+FL  EAA+VF MGFATN++NIP LV K C ++SDELNH SL+LG RLSGA  R FKHNN +SLE+ L  A+  G  +T+R +KKIL++VEGVYSMEGSIV LP+I+ LKKKYK Y+Y+DEAHSIGA+G  GRGV ++F L+PHEVD+ MGTFTKSF +SGGYI+G ++L+ Y+R  SHS +Y  +MS PI +QI+ ++ +I G  G + G +R++QLA NT YFR  L  MG I++GN+N+ V+P+++Y   KV AF R  + + IG V+VG+PA  L  AR RFC+SAAHT+  LD  L  +DE+   L+ KYSR
Sbjct:   32 NGIVKEAQQNGKPHFYDKLIVESFEEAPLHVMVFTYMGYGIGTLFGYLRDFLRNWGIEKCNAAVERKEQKDFVPLYQDFENFYTRNLYMRIRDNWNRPICSAPGPLFDLMERVSDDYNWTFRFTGRVIKDVINMGSYNFLGLAAKYDESMRTIKDVLEVYGTGVASTRHEMGTLDKHKELEDLVAKFLNVEAAMVFGMGFATNSMNIPALVGKGCLILSDELNHTSLVLGARLSGATIRIFKHNNTQSLEKLLRDAVIYGQPRTRRAWKKILILVEGVYSMEGSIVHLPQIIALKKKYKAYLYIDEAHSIGAVGPTGRGVTEFFGLDPHEVDVLMGTFTKSFGASGGYIAGRKDLVDYLRVHSHSAVYASSMSPPIAEQIIRSLKLIMGLDGTTQGLQRVQQLAKNTRYFRQRLQEMGFIIYGNENASVVPLLLYMPGKVAAFARHMLEKKIGVVVVGFPATPLAEARARFCVSAAHTREMLDTVLEALDEMGDLLQLKYSR 533
[Close]
BLAST of Serine palmitoyltransferase 2 vs. Ensembl Human
Match: SPTLC2 (serine palmitoyltransferase long chain base subunit 2 [Source:HGNC Symbol;Acc:HGNC:11278])

HSP 1 Score: 415.616 bits (1067), Expect = 2.161e-140
Identity = 201/371 (54.18%), Postives = 264/371 (71.16%), Query Frame = 1 
Query:  106 KASLFNSLITYLYFFILKCMGKLRDFMRNYGLEKNRLAVDSTKNKGFAPLYLDFEAFYTRNVYRRVCDCVNKPICSAPGGSLKAMNRVSDDHNWTFRILDST-SDIYNFGSYNYLGFAQNDGLCTDYVEKSINEFGLSVGSPRQEVGNTLYHLELEESLAEFLGQEAAIVFPMGFATNALNIPILVDKDCCVISDELNHVSLILGIRLSGADTRRFKHNNVESLERELIKAITEGHSKTKRKFKKILVVVEGVYSMEGSIVRLPEILELKKKYKFYIYLDEAHSIGALGKGGRGVVDYFNLNPHEVDIQMGTFTKSFASSGGYISGSRNLIHYVREKSHSTIYGGTMSGPICQQILSAMAIIGGKMGGSLG 1215
            +  +  +++TY+ + +L   G LRDF+R + +EK   A +  + K F  LY DFE FYTRN+Y R+ D  N+PICS PG  +  M R S D+NW+F+   +    + N GSYNYLGFA+N G C +   K + E+G  V S RQE+GN   H ELEE +A FLG EAA+ + MGFATN++NIP LV K C ++SDELNH SL+LG RLSGA  R FKHNN++SLE+ L  AI  G  +T+R +KKIL++VEG+YSMEGSIVRLPE++ LKKKYK Y+YLDEAHSIGALG  GRGVV+YF L+P +VD+ MGTFTKSF +SGGYI G + LI Y+R  SHS +Y  ++S P+ +QI+++M  I G+ G SLG
Sbjct:    2 ETPMLVAVLTYVGYGVLTLFGYLRDFLRYWRIEKCHHATEREEQKDFVSLYQDFENFYTRNLYMRIRDNWNRPICSVPGARVDIMERQSHDYNWSFKYTGNIIKGVINMGSYNYLGFARNTGSCQEAAAKVLEEYGAGVCSTRQEIGNLDKHEELEELVARFLGVEAAMAYGMGFATNSMNIPALVGKGCLILSDELNHASLVLGARLSGATIRIFKHNNMQSLEKLLKDAIVYGQPRTRRPWKKILILVEGIYSMEGSIVRLPEVIALKKKYKAYLYLDEAHSIGALGPTGRGVVEYFGLDPEDVDVMMGTFTKSFGASGGYIGGKKELIDYLRTHSHSAVYATSLSPPVVEQIITSMKCIMGQDGTSLG 372
[Close]
BLAST of Serine palmitoyltransferase 2 vs. Ensembl Human
Match: GCAT (glycine C-acetyltransferase [Source:HGNC Symbol;Acc:HGNC:4188])

HSP 1 Score: 153.68 bits (387), Expect = 4.872e-40
Identity = 109/372 (29.30%), Postives = 182/372 (48.92%), Query Frame = 1 
Query:  397 ILDSTSDIYNFGSYNYLGFAQNDGLCTDYVEKSINEFGLSVGSPRQEVGNTLYHLELEESLAEFLGQEAAIVFPMGFATNALNIPILVDKDCCVISDELNHVSLILGIRLSGADTRRFKHNNVESLERELIKAITEGHSKTKRKFKKILVVVEGVYSMEGSIVRLPEILELKKKYKFYIYLDEAHSIGALGKGGRGVVDYFNLNPHEVDIQMGTFTKSF-ASSGGYISGSRNLIHYVREKSHSTIYGGTMSGPICQQILSAMAIIGGKMGGSLGAERIRQ-LAWNTTYFRAALHRMGLIVFGNKNSPVIPVIVYTIPKVVAFHRECMRRGIGTVIVGYPACNLKLARIRFCISAAHTKRSLDYTLSIVDEIA 1506
            +L  TS I NF + NYLG + +  +    ++ ++ EFG  + S R   G    H  LE  +A F  +E AI++P  +  NA     L+  +  V+SDELNH S+I GIRL  A   R++H ++  LE +L +A         +K +  LV  +G +SM+G I  L EI  L  +Y   +++DE H+ G LG  GRG  +   +   +V I   T  K+   +SGGY +G   L+  +R+++   ++  ++   +      A+ ++       +G+  I Q +A  T  FR+ +   G  + G  + P+ PV++           + ++RGI  +   YP      ARIR  ISA H++  +D  +    E+ 
Sbjct:   86 LLSFTSGILNFCANNYLGLSSHPEVIQAGLQ-ALEEFGAGLSSVRFICGTQSIHKNLEAKIARFHQREDAILYPSCYDANAGLFEALLTPEDAVLSDELNHASIIDGIRLCKAHKYRYRHLDMADLEAKLQEA---------QKHRLRLVATDGAFSMDGDIAPLQEICCLASRYGALVFMDECHATGFLGPTGRGTDELLGVM-DQVTIINSTLGKALGGASGGYTTGPGPLVSLLRQRARPYLFSNSLPPAVVGCASKALDLL-------MGSNTIVQSMAAKTQRFRSKMEAAGFTISGASH-PICPVMLGDARLASRMADDMLKRGIFVIGFSYPVVPKGKARIRVQISAVHSEEDIDRCVEAFVEVG 438
[Close]
BLAST of Serine palmitoyltransferase 2 vs. Ensembl Human
Match: GCAT (glycine C-acetyltransferase [Source:HGNC Symbol;Acc:HGNC:4188])

HSP 1 Score: 151.754 bits (382), Expect = 1.141e-39
Identity = 109/389 (28.02%), Postives = 187/389 (48.07%), Query Frame = 1 
Query:  343 GSLKAMNRVSDDHNWTFRILDSTSDIYNFGSYNYLGFAQNDGLCTDYVEKSINEFGLSVGSPRQEVGNTLYHLELEESLAEFLGQEAAIVFPMGFATNALNIPILVDKDCCVISDELNHVSLILGIRLSGADTRRFKHNNVESLERELIKAITEGHSKTKRKFKKILVVVEGVYSMEGSIVRLPEILELKKKYKFYIYLDEAHSIGALGKGGRGVVDYFNLNPHEVDIQMGTFTKSF-ASSGGYISGSRNLIHYVREKSHSTIYGGTMSGPICQQILSAMAIIGGKMGGSLGAERIRQ-LAWNTTYFRAALHRMGLIVFGNKNSPVIPVIVYTIPKVVAFHRECMRRGIGTVIVGYPACNLKLARIRFCISAAHTKRSLDYTLSIVDEI 1503
            G+ K+   ++       R+   +  I NF + NYLG + +  +    ++ ++ EFG  + S R   G    H  LE  +A F  +E AI++P  +  NA     L+  +  V+SDELNH S+I GIRL  A   R++H ++  LE +L +A         +K +  LV  +G +SM+G I  L EI  L  +Y   +++DE H+ G LG  GRG  +   +   +V I   T  K+   +SGGY +G   L+  +R+++   ++  ++   +      A+ ++       +G+  I Q +A  T  FR+ +   G  + G  + P+ PV++           + ++RGI  +   YP      ARIR  ISA H++  +D  +    E+
Sbjct:   42 GTWKSERVITSRQGPHIRVDGVSGGILNFCANNYLGLSSHPEVIQAGLQ-ALEEFGAGLSSVRFICGTQSIHKNLEAKIARFHQREDAILYPSCYDANAGLFEALLTPEDAVLSDELNHASIIDGIRLCKAHKYRYRHLDMADLEAKLQEA---------QKHRLRLVATDGAFSMDGDIAPLQEICCLASRYGALVFMDECHATGFLGPTGRGTDELLGVM-DQVTIINSTLGKALGGASGGYTTGPGPLVSLLRQRARPYLFSNSLPPAVVGCASKALDLL-------MGSNTIVQSMAAKTQRFRSKMEAAGFTISGASH-PICPVMLGDARLASRMADDMLKRGIFVIGFSYPVVPKGKARIRVQISAVHSEEDIDRCVEAFVEV 411
[Close]
BLAST of Serine palmitoyltransferase 2 vs. Ensembl Celegans
Match: sptl-2 (Serine palmitoyltransferase 2 [Source:UniProtKB/Swiss-Prot;Acc:Q20375])

HSP 1 Score: 471.47 bits (1212), Expect = 1.805e-160
Identity = 234/480 (48.75%), Postives = 326/480 (67.92%), Query Frame = 1 
Query:   97 QFEKASLFNSLITYLYFFILKCMGKLRDFMRNYGLEKNRLAVDSTKNKGFAPLYLDFEAFYTRNVYRRVCDCVNKPICSAPGGSLKAMNRVSDDHNWTFRILDSTSDIYNFGSYNYLGFAQNDGLCTDYVEKSINEFGLSVGSPRQEVGNTLYHLELEESLAEFLGQEAAIVFPMGFATNALNIPILVDKDCCVISDELNHVSLILGIRLSGADTRRFKHNNVESLERELIKAITEGHSKTKRKFKKILVVVEGVYSMEGSIVRLPEILELKKKYKFYIYLDEAHSIGALGKGGRGVVDYFNLNPHEVDIQMGTFTKSFASSGGYISGSRNLIHYVREKSHSTIYGGTMSGPICQQILSAMAIIGGKMGGSLGAERIRQLAWNTTYFRAALHRMGLIVFGNKNSPVIPVIVYTIPKVVAFH-RECMRRGIGTVIVGYPACNLKLARIRFCISAAHTKRSLDYTLSIVDEIATHLRFKYSR 1533
            +FEK     ++  Y+ +  L     +R+++  +G  K+  + ++ K K F PL+ DFEAFY RN Y +V D   +PICS PG ++  ++RVS D NWT+    + +++ N GSYNYLGFAQ+ G C +    SI+  GLS  +   E G ++   +LE+ +AEFLG E AI F MGFATN++N P LVDK   +ISD+ NH SLILG RLSGA T+ F+HN++ESLER L  AI  G+ KT R +KKIL++VEG+YSMEGSI  LP I+ LKKKY+ Y+YLDEAHSIGA+GK G+GVV+Y+  +P +VDI MGTFTKSF ++GGYI+GS+  + ++R  S +  Y   MS PI QQI ++M+II GK G   GA+RI +LA N+ YFR  L + G IV+G+ +SPV+P+++Y  P +  F+ RE + R IG V+V +PA ++   R+RFCISAAHTK  LD  L  V+ + +  R K+S+
Sbjct:   68 EFEKIDRLTTIKVYIAWLALFVFAHIREYVTRFGFVKDLSSKENAKMKDFVPLFSDFEAFYQRNCYIKVRDVFERPICSVPGATVDLVDRVSHDGNWTYEYPGTRTNVINVGSYNYLGFAQSAGPCAEQSASSIDREGLSCCTTVHERGRSVSQAKLEKLVAEFLGVEDAICFSMGFATNSMNAPCLVDKHSLIISDKYNHASLILGCRLSGASTKVFEHNDMESLERILRDAIAYGNPKTHRPYKKILIIVEGIYSMEGSICNLPGIIALKKKYQAYLYLDEAHSIGAMGKTGKGVVEYWGCDPKDVDILMGTFTKSFGAAGGYIAGSKRTVDHLRAASPTGYYSSPMSPPIAQQIYTSMSIIMGKDGTKDGAQRIERLARNSHYFRMKLKQNGFIVYGSNDSPVVPMLIY-FPTMCGFYGREMLARNIGCVVVSFPATHMTEGRVRFCISAAHTKEQLDEVLETVNLLGSMSRSKFSK 546
[Close]
BLAST of Serine palmitoyltransferase 2 vs. Ensembl Celegans
Match: sptl-2 (Serine palmitoyltransferase 2 [Source:UniProtKB/Swiss-Prot;Acc:Q20375])

HSP 1 Score: 471.855 bits (1213), Expect = 3.642e-160
Identity = 234/480 (48.75%), Postives = 326/480 (67.92%), Query Frame = 1 
Query:   97 QFEKASLFNSLITYLYFFILKCMGKLRDFMRNYGLEKNRLAVDSTKNKGFAPLYLDFEAFYTRNVYRRVCDCVNKPICSAPGGSLKAMNRVSDDHNWTFRILDSTSDIYNFGSYNYLGFAQNDGLCTDYVEKSINEFGLSVGSPRQEVGNTLYHLELEESLAEFLGQEAAIVFPMGFATNALNIPILVDKDCCVISDELNHVSLILGIRLSGADTRRFKHNNVESLERELIKAITEGHSKTKRKFKKILVVVEGVYSMEGSIVRLPEILELKKKYKFYIYLDEAHSIGALGKGGRGVVDYFNLNPHEVDIQMGTFTKSFASSGGYISGSRNLIHYVREKSHSTIYGGTMSGPICQQILSAMAIIGGKMGGSLGAERIRQLAWNTTYFRAALHRMGLIVFGNKNSPVIPVIVYTIPKVVAFH-RECMRRGIGTVIVGYPACNLKLARIRFCISAAHTKRSLDYTLSIVDEIATHLRFKYSR 1533
            +FEK     ++  Y+ +  L     +R+++  +G  K+  + ++ K K F PL+ DFEAFY RN Y +V D   +PICS PG ++  ++RVS D NWT+    + +++ N GSYNYLGFAQ+ G C +    SI+  GLS  +   E G ++   +LE+ +AEFLG E AI F MGFATN++N P LVDK   +ISD+ NH SLILG RLSGA T+ F+HN++ESLER L  AI  G+ KT R +KKIL++VEG+YSMEGSI  LP I+ LKKKY+ Y+YLDEAHSIGA+GK G+GVV+Y+  +P +VDI MGTFTKSF ++GGYI+GS+  + ++R  S +  Y   MS PI QQI ++M+II GK G   GA+RI +LA N+ YFR  L + G IV+G+ +SPV+P+++Y  P +  F+ RE + R IG V+V +PA ++   R+RFCISAAHTK  LD  L  V+ + +  R K+S+
Sbjct:   96 EFEKIDRLTTIKVYIAWLALFVFAHIREYVTRFGFVKDLSSKENAKMKDFVPLFSDFEAFYQRNCYIKVRDVFERPICSVPGATVDLVDRVSHDGNWTYEYPGTRTNVINVGSYNYLGFAQSAGPCAEQSASSIDREGLSCCTTVHERGRSVSQAKLEKLVAEFLGVEDAICFSMGFATNSMNAPCLVDKHSLIISDKYNHASLILGCRLSGASTKVFEHNDMESLERILRDAIAYGNPKTHRPYKKILIIVEGIYSMEGSICNLPGIIALKKKYQAYLYLDEAHSIGAMGKTGKGVVEYWGCDPKDVDILMGTFTKSFGAAGGYIAGSKRTVDHLRAASPTGYYSSPMSPPIAQQIYTSMSIIMGKDGTKDGAQRIERLARNSHYFRMKLKQNGFIVYGSNDSPVVPMLIY-FPTMCGFYGREMLARNIGCVVVSFPATHMTEGRVRFCISAAHTKEQLDEVLETVNLLGSMSRSKFSK 574
[Close]
BLAST of Serine palmitoyltransferase 2 vs. Ensembl Celegans
Match: sptl-3 (Serine palmitoyltransferase 3 [Source:UniProtKB/Swiss-Prot;Acc:Q9XVI6])

HSP 1 Score: 436.417 bits (1121), Expect = 1.995e-147
Identity = 204/438 (46.58%), Postives = 292/438 (66.67%), Query Frame = 1 
Query:  193 YGLEKNRLAVDSTKNKGFAPLYLDFEAFYTRNVYRRVCDCVNKPICSAPGGSLKAMNRVSDDHNWTFRILDSTSDIYNFGSYNYLGFAQNDGLCTDYVEKSINEFGLSVGSPRQEVGNTLYHLELEESLAEFLGQEAAIVFPMGFATNALNIPILVDKDCCVISDELNHVSLILGIRLSGADTRRFKHNNVESLERELIKAITEGHSKTKRKFKKILVVVEGVYSMEGSIVRLPEILELKKKYKFYIYLDEAHSIGALGKGGRGVVDYFNLNPHEVDIQMGTFTKSFASSGGYISGSRNLIHYVREKSHSTIYGGTMSGPICQQILSAMAIIGGKMGGSLGAERIRQLAWNTTYFRAALHRMGLIVFGNKNSPVIPVIVYTIPKVVAFHRECMRRGIGTVIVGYPACNLKLARIRFCISAAHTKRSLDYTLSIVDEIA 1506
            +G+ K + +    + + F PL   F+A YT ++YR+  D VN+PI   PG  ++  +R +DDH WT +   + S++ N GSYNYLGF+   G+C +     I+++G++ G  RQE+GN + H  +E ++A++L  E AIVFPMGFATN++NIP LVDK   ++SD LNH SL+ G RLSGA T  F+HN+    ER+L  A+     KT  K+ K+L+++EG+YSMEG+IV LP  + +KKKY  Y++LDEAHSIGA+G  GRGV +Y+  NP ++DI MGT TKSFAS+GGY+ GS+ +I ++R  S  T YG TMS P+  Q+  A+ I+ GK G  +G ++  QL  N+ YFR  L + G +V+GN +SPV+P++ + I KVV F R  ++  IG V VGYPA  L  AR+RFC+SA HTK  LDY L  V+++ 
Sbjct:   61 WGIVKTKRSKGDPRMESFQPLGNSFDATYTDHIYRQSTDVVNRPISGVPGAIVRLKDRYTDDHGWTQKYTGTESEVINLGSYNYLGFSHRSGVCAEAAAAHIDKYGINCGGSRQEIGNHVAHKSVESTIAQYLNVEDAIVFPMGFATNSMNIPSLVDKGSLILSDRLNHASLVTGCRLSGAHTVVFRHNDASDCERKLRDALCGVSPKTGEKYNKVLIIIEGIYSMEGTIVNLPAFIAVKKKYNCYLFLDEAHSIGAVGPSGRGVAEYWGCNPRDIDIMMGTLTKSFASAGGYMGGSKKVIDHIRRYSAGTCYGVTMSPPLIAQVERAVLIMSGKDGTDIGRQKAIQLLENSRYFRKELRKRGFLVYGNNDSPVVPLMTFYITKVVEFSRRMLKHNIGIVAVGYPATPLLEARVRFCLSADHTKEHLDYILEAVEQVG 498
[Close]
BLAST of Serine palmitoyltransferase 2 vs. Ensembl Celegans
Match: sptl-3 (Serine palmitoyltransferase 3 [Source:UniProtKB/Swiss-Prot;Acc:Q9XVI6])

HSP 1 Score: 436.417 bits (1121), Expect = 1.995e-147
Identity = 204/438 (46.58%), Postives = 292/438 (66.67%), Query Frame = 1 
Query:  193 YGLEKNRLAVDSTKNKGFAPLYLDFEAFYTRNVYRRVCDCVNKPICSAPGGSLKAMNRVSDDHNWTFRILDSTSDIYNFGSYNYLGFAQNDGLCTDYVEKSINEFGLSVGSPRQEVGNTLYHLELEESLAEFLGQEAAIVFPMGFATNALNIPILVDKDCCVISDELNHVSLILGIRLSGADTRRFKHNNVESLERELIKAITEGHSKTKRKFKKILVVVEGVYSMEGSIVRLPEILELKKKYKFYIYLDEAHSIGALGKGGRGVVDYFNLNPHEVDIQMGTFTKSFASSGGYISGSRNLIHYVREKSHSTIYGGTMSGPICQQILSAMAIIGGKMGGSLGAERIRQLAWNTTYFRAALHRMGLIVFGNKNSPVIPVIVYTIPKVVAFHRECMRRGIGTVIVGYPACNLKLARIRFCISAAHTKRSLDYTLSIVDEIA 1506
            +G+ K + +    + + F PL   F+A YT ++YR+  D VN+PI   PG  ++  +R +DDH WT +   + S++ N GSYNYLGF+   G+C +     I+++G++ G  RQE+GN + H  +E ++A++L  E AIVFPMGFATN++NIP LVDK   ++SD LNH SL+ G RLSGA T  F+HN+    ER+L  A+     KT  K+ K+L+++EG+YSMEG+IV LP  + +KKKY  Y++LDEAHSIGA+G  GRGV +Y+  NP ++DI MGT TKSFAS+GGY+ GS+ +I ++R  S  T YG TMS P+  Q+  A+ I+ GK G  +G ++  QL  N+ YFR  L + G +V+GN +SPV+P++ + I KVV F R  ++  IG V VGYPA  L  AR+RFC+SA HTK  LDY L  V+++ 
Sbjct:   61 WGIVKTKRSKGDPRMESFQPLGNSFDATYTDHIYRQSTDVVNRPISGVPGAIVRLKDRYTDDHGWTQKYTGTESEVINLGSYNYLGFSHRSGVCAEAAAAHIDKYGINCGGSRQEIGNHVAHKSVESTIAQYLNVEDAIVFPMGFATNSMNIPSLVDKGSLILSDRLNHASLVTGCRLSGAHTVVFRHNDASDCERKLRDALCGVSPKTGEKYNKVLIIIEGIYSMEGTIVNLPAFIAVKKKYNCYLFLDEAHSIGAVGPSGRGVAEYWGCNPRDIDIMMGTLTKSFASAGGYMGGSKKVIDHIRRYSAGTCYGVTMSPPLIAQVERAVLIMSGKDGTDIGRQKAIQLLENSRYFRKELRKRGFLVYGNNDSPVVPLMTFYITKVVEFSRRMLKHNIGIVAVGYPATPLLEARVRFCLSADHTKEHLDYILEAVEQVG 498
[Close]
BLAST of Serine palmitoyltransferase 2 vs. Ensembl Celegans
Match: sptl-3 (Serine palmitoyltransferase 3 [Source:UniProtKB/Swiss-Prot;Acc:Q9XVI6])

HSP 1 Score: 436.802 bits (1122), Expect = 2.062e-147
Identity = 204/438 (46.58%), Postives = 292/438 (66.67%), Query Frame = 1 
Query:  193 YGLEKNRLAVDSTKNKGFAPLYLDFEAFYTRNVYRRVCDCVNKPICSAPGGSLKAMNRVSDDHNWTFRILDSTSDIYNFGSYNYLGFAQNDGLCTDYVEKSINEFGLSVGSPRQEVGNTLYHLELEESLAEFLGQEAAIVFPMGFATNALNIPILVDKDCCVISDELNHVSLILGIRLSGADTRRFKHNNVESLERELIKAITEGHSKTKRKFKKILVVVEGVYSMEGSIVRLPEILELKKKYKFYIYLDEAHSIGALGKGGRGVVDYFNLNPHEVDIQMGTFTKSFASSGGYISGSRNLIHYVREKSHSTIYGGTMSGPICQQILSAMAIIGGKMGGSLGAERIRQLAWNTTYFRAALHRMGLIVFGNKNSPVIPVIVYTIPKVVAFHRECMRRGIGTVIVGYPACNLKLARIRFCISAAHTKRSLDYTLSIVDEIA 1506
            +G+ K + +    + + F PL   F+A YT ++YR+  D VN+PI   PG  ++  +R +DDH WT +   + S++ N GSYNYLGF+   G+C +     I+++G++ G  RQE+GN + H  +E ++A++L  E AIVFPMGFATN++NIP LVDK   ++SD LNH SL+ G RLSGA T  F+HN+    ER+L  A+     KT  K+ K+L+++EG+YSMEG+IV LP  + +KKKY  Y++LDEAHSIGA+G  GRGV +Y+  NP ++DI MGT TKSFAS+GGY+ GS+ +I ++R  S  T YG TMS P+  Q+  A+ I+ GK G  +G ++  QL  N+ YFR  L + G +V+GN +SPV+P++ + I KVV F R  ++  IG V VGYPA  L  AR+RFC+SA HTK  LDY L  V+++ 
Sbjct:   70 WGIVKTKRSKGDPRMESFQPLGNSFDATYTDHIYRQSTDVVNRPISGVPGAIVRLKDRYTDDHGWTQKYTGTESEVINLGSYNYLGFSHRSGVCAEAAAAHIDKYGINCGGSRQEIGNHVAHKSVESTIAQYLNVEDAIVFPMGFATNSMNIPSLVDKGSLILSDRLNHASLVTGCRLSGAHTVVFRHNDASDCERKLRDALCGVSPKTGEKYNKVLIIIEGIYSMEGTIVNLPAFIAVKKKYNCYLFLDEAHSIGAVGPSGRGVAEYWGCNPRDIDIMMGTLTKSFASAGGYMGGSKKVIDHIRRYSAGTCYGVTMSPPLIAQVERAVLIMSGKDGTDIGRQKAIQLLENSRYFRKELRKRGFLVYGNNDSPVVPLMTFYITKVVEFSRRMLKHNIGIVAVGYPATPLLEARVRFCLSADHTKEHLDYILEAVEQVG 507
[Close]
BLAST of Serine palmitoyltransferase 2 vs. Ensembl Fly
Match: lace (gene:FBgn0002524 transcript:FBtr0343735)

HSP 1 Score: 483.411 bits (1243), Expect = 1.685e-164
Identity = 249/514 (48.44%), Postives = 334/514 (64.98%), Query Frame = 1 
Query:   37 NGHIKSIKQETK--------CKESEFFEQ--FEKASLFNSLITYLYFFILKCMGKLRD--FMRNYGLEKNRLAVDSTKNKGFAPLYLDFEAFYTRNVYRRVCDCVNKPICSAPGGSLKAMNRVSDDHNWTFRILDSTSDIYNFGSYNYLGFAQNDGLCTDYVEKSINEFGLSVGSPRQEVGNTLYHLELEESLAEFLGQEAAIVFPMGFATNALNIPILVDKDCCVISDELNHVSLILGIRLSGADTRRFKHNNVESLERELIKAITEGHSKTK-RKFKKILVVVEGVYSMEGSIVRLPEILELKKKYKFYIYLDEAHSIGALGKGGRGVVDYFNLNPHEVDIQMGTFTKSFASSGGYISGSRNLIHYVREKSHSTIYGGTMSGPICQQILSAMAIIGGKMGGSLGAERIRQLAWNTTYFRAALHRMGLIVFGNKNSPVIPVIVYTIPKVVAFHRECMRRGIGTVIVGYPACNLKLARIRFCISAAHTKRSLDYTLSIVDEIATHLRFKYSRLP 1539
            NGH   + QE+K          E E F++  FE+  L  + +TYL F++L  +G +    F+     EK R         G+  LY  FE+FY+R VYRR+ DC N+PICS PG  L   +RV+DD+ W+F+   + +   N GSYNYLGFA   G C D  E+S    GL+  S R E+G+     ELE   A + G E AIVF MGFATNALN+P L+  +  VISDE NH S+ILG+RLSGA T+ FKHNN+  LER L + +  G+ K   + + K++++VEG++SMEGSIVRLPE++ LKKKYK Y+YLDEAHS+GA+G  GRGV DYFN++P EVDI MGTFTKSF S+GGY++GS+ LI ++R  SH+  Y  ++S PI QQIL++M  I G+ G  +G ++I QLA NT YFR  L ++G+I +G+++SPV+P++VY   K+ A  R    R I  V  G+PA  +   RIRFC+SAAHTK  LD+ L  +DEIA  L  KYSR P
Sbjct:   84 NGHASILDQESKPNQAEGKLSPELEHFQKTSFEEVPLHTACLTYLGFYLLMILGYINQLLFVPKVATEKGR--------DGYVALYDAFESFYSRYVYRRIKDCWNRPICSVPGDELTLKDRVTDDYGWSFKFTGTETRCLNLGSYNYLGFAAATGQCADDSEESARSSGLAYCSSRCELGDNEQLQELEALTARYFGVEDAIVFGMGFATNALNLPSLLGPNSLVISDEKNHASIILGLRLSGATTKVFKHNNMRDLERVLRQGVCYGNPKKGGQPWDKVMILVEGIFSMEGSIVRLPEVIALKKKYKAYLYLDEAHSVGAMGSRGRGVTDYFNVDPKEVDILMGTFTKSFGSAGGYLAGSKKLIDFLRTNSHAHCYAASISPPIAQQILTSMKTIMGEDGTDIGRKKIHQLARNTRYFRRRLAQLGVITYGHEDSPVVPMLVYLFSKIGAVVRTLTTRHIAAVGAGFPATPIMEGRIRFCLSAAHTKEQLDFALEAIDEIADDLGLKYSRKP 589
[Close]
BLAST of Serine palmitoyltransferase 2 vs. Ensembl Fly
Match: lace (gene:FBgn0002524 transcript:FBtr0080738)

HSP 1 Score: 483.411 bits (1243), Expect = 1.685e-164
Identity = 249/514 (48.44%), Postives = 334/514 (64.98%), Query Frame = 1 
Query:   37 NGHIKSIKQETK--------CKESEFFEQ--FEKASLFNSLITYLYFFILKCMGKLRD--FMRNYGLEKNRLAVDSTKNKGFAPLYLDFEAFYTRNVYRRVCDCVNKPICSAPGGSLKAMNRVSDDHNWTFRILDSTSDIYNFGSYNYLGFAQNDGLCTDYVEKSINEFGLSVGSPRQEVGNTLYHLELEESLAEFLGQEAAIVFPMGFATNALNIPILVDKDCCVISDELNHVSLILGIRLSGADTRRFKHNNVESLERELIKAITEGHSKTK-RKFKKILVVVEGVYSMEGSIVRLPEILELKKKYKFYIYLDEAHSIGALGKGGRGVVDYFNLNPHEVDIQMGTFTKSFASSGGYISGSRNLIHYVREKSHSTIYGGTMSGPICQQILSAMAIIGGKMGGSLGAERIRQLAWNTTYFRAALHRMGLIVFGNKNSPVIPVIVYTIPKVVAFHRECMRRGIGTVIVGYPACNLKLARIRFCISAAHTKRSLDYTLSIVDEIATHLRFKYSRLP 1539
            NGH   + QE+K          E E F++  FE+  L  + +TYL F++L  +G +    F+     EK R         G+  LY  FE+FY+R VYRR+ DC N+PICS PG  L   +RV+DD+ W+F+   + +   N GSYNYLGFA   G C D  E+S    GL+  S R E+G+     ELE   A + G E AIVF MGFATNALN+P L+  +  VISDE NH S+ILG+RLSGA T+ FKHNN+  LER L + +  G+ K   + + K++++VEG++SMEGSIVRLPE++ LKKKYK Y+YLDEAHS+GA+G  GRGV DYFN++P EVDI MGTFTKSF S+GGY++GS+ LI ++R  SH+  Y  ++S PI QQIL++M  I G+ G  +G ++I QLA NT YFR  L ++G+I +G+++SPV+P++VY   K+ A  R    R I  V  G+PA  +   RIRFC+SAAHTK  LD+ L  +DEIA  L  KYSR P
Sbjct:   84 NGHASILDQESKPNQAEGKLSPELEHFQKTSFEEVPLHTACLTYLGFYLLMILGYINQLLFVPKVATEKGR--------DGYVALYDAFESFYSRYVYRRIKDCWNRPICSVPGDELTLKDRVTDDYGWSFKFTGTETRCLNLGSYNYLGFAAATGQCADDSEESARSSGLAYCSSRCELGDNEQLQELEALTARYFGVEDAIVFGMGFATNALNLPSLLGPNSLVISDEKNHASIILGLRLSGATTKVFKHNNMRDLERVLRQGVCYGNPKKGGQPWDKVMILVEGIFSMEGSIVRLPEVIALKKKYKAYLYLDEAHSVGAMGSRGRGVTDYFNVDPKEVDILMGTFTKSFGSAGGYLAGSKKLIDFLRTNSHAHCYAASISPPIAQQILTSMKTIMGEDGTDIGRKKIHQLARNTRYFRRRLAQLGVITYGHEDSPVVPMLVYLFSKIGAVVRTLTTRHIAAVGAGFPATPIMEGRIRFCLSAAHTKEQLDFALEAIDEIADDLGLKYSRKP 589
[Close]
BLAST of Serine palmitoyltransferase 2 vs. Ensembl Fly
Match: CG10361 (gene:FBgn0036208 transcript:FBtr0076084)

HSP 1 Score: 190.274 bits (482), Expect = 5.686e-54
Identity = 123/394 (31.22%), Postives = 200/394 (50.76%), Query Frame = 1 
Query:  340 GGSLKAMNRVSDDHNWTFRILDSTSDIYNFGSYNYLGFAQNDGLCTDYVEKSINEFGLSVGSPRQEVGNTLYHLELEESLAEFLGQEAAIVFPMGFATNALNIPILVDKDCCVISDELNHVSLILGIRLSGADTRRFKHNNVESLERELIKAITEGHSKTKRKFKKILVVVEGVYSMEGSIVRLPEILELKKKYKFYIYLDEAHSIGALGKGGRGVVDYFNLNPHEVDIQMGTFTKSF-ASSGGYISGSRNLIHYVREKSHSTIYGGTMSGPICQQILSAMAIIGGKMGGSLGAERIRQLAWNTTYFRAALHRMGLIVFGNKNSPVIPVIVYTIPKVVAFHRECMRRGIGTVIVGYPACNLKLARIRFCISAAHTKRSLDYTLSIVDEIATHLR 1518
             G+ KA   ++   +    +  S   I NF + NYLG A N  +  ++ +K + ++G  + S R   G    H +LE+ +A+F G+E  I++   F  NA     ++  +  V SDELNH S+I GIRL  A  +R++H ++  LE +L          +  + K  L+  +GV+SM+G+I  L  I+EL +KY   +++DE H+ G  G  GRG  +Y N+   EVDI   T  K+   +SGGY +G   LI ++R+KS   ++  T+   +    L  M ++         +E  +++  NT  FR A+ + G  + G +N P+ PV++        F  E + RGI  +   YP      ARIR  ISAAHT+  +D  ++   E+   L+
Sbjct:   40 AGTFKAERIITSSQSTQITVQGSDKKILNFCANNYLGLANNPEIV-EHSQKLLEQYGAGLSSVRFICGTQDIHKQLEKKIAQFHGREDTILYASCFDANAGIFEAILTPEDAVFSDELNHASIIDGIRLCKAKKQRYRHRDLGDLEEQL--------KASDARLK--LIATDGVFSMDGNIAPLARIVELARKYNALVFVDECHATGFFGATGRGTEEYDNVMG-EVDIINSTLGKALGGASGGYTTGPAELISFLRQKSRPYLFSNTLPPAVVAVGLKVMDML------LQSSELTQRVQSNTQRFRQAMTKAGFTIAG-ENHPICPVMLGDARLASQFADEMLTRGIYVIGFSYPVVPQGKARIRVQISAAHTEAEIDRAINAFIEVGRSLK 414
[Close]
BLAST of Serine palmitoyltransferase 2 vs. Ensembl Fly
Match: Spt-I (gene:FBgn0086532 transcript:FBtr0087731)

HSP 1 Score: 152.525 bits (384), Expect = 7.623e-40
Identity = 108/353 (30.59%), Postives = 172/353 (48.73%), Query Frame = 1 
Query:  394 RILDSTSDIYNFGSYNYLGFAQNDGLCTDYVEKSINEFGLSVGSPRQEVGNTLYHLELEESLAEFLGQEAAIVFPMGFATNALNIPILVDKDCCVISDELNHVSLILGIRLSGADTRRFKHNNVESLERELIKAITEGHSKTKRKFK-KILVVVEGVYSMEGSIVRLPEILELKKKYKFYIYLDEAHSIGALGKGGRGVVDYFNLNPHEVDIQMGTFTKSFASSGGYISGSRNLIHYVREKSHSTIYGGTMSGPICQQILSAMAIIGGKMGGSLGAERIRQL-----AWNTTYFRAALHRMGLIVFGNKNSPVIPVIVYTIPKVVAFHRE----------CMRRGIGTVIVGY 1404
            RI     D  N GS+NYLGF ++  +  +   KS+ ++G+    PR   G    HL+LE+ +A+F+G E AIV+  GF+T A  IP    +   +  DE  + ++  G+  S +    FKHN+VE LER LI+         K+  K +  +V EG+Y   G I  LP+++ L++KYK  +++DE+ S G LG+GG GV ++FN++  EVD+       S A+ GG+  GS  +  + R      I+  ++   + Q  +SA+             ER  Q+     A + T  +  L    L + G++ SPV    +Y       F +E          C+ RG+  V   Y
Sbjct:   88 RIQVDGHDCLNLGSHNYLGFLEDQEILEEAC-KSLRKYGVGSCGPRGFYGTMDVHLDLEDRIAKFMGLEEAIVYSYGFSTVASAIPAYAKRGDLIFVDEAVNFAIQKGLDASRSTIVFFKHNDVEDLERLLIEQEKRDQKNPKKAAKTRRFLVAEGIYMNTGEICPLPDLVALRQKYKLRLFIDESISFGTLGQGGHGVTEHFNVDRDEVDLISAGMEGSMATVGGFCVGSHFIAEHQRLSGLGYIFSASLPPMLTQAAISALDRF----------EREPQIFEQLQAKSKTLHQKFLRFSKLTLRGDEVSPVKH--LYLAQPAENFDKELKLLTELADKCIARGVAVVQAAY 427
[Close]
BLAST of Serine palmitoyltransferase 2 vs. Ensembl Fly
Match: Spt-I (gene:FBgn0086532 transcript:FBtr0087729)

HSP 1 Score: 152.525 bits (384), Expect = 7.623e-40
Identity = 108/353 (30.59%), Postives = 172/353 (48.73%), Query Frame = 1 
Query:  394 RILDSTSDIYNFGSYNYLGFAQNDGLCTDYVEKSINEFGLSVGSPRQEVGNTLYHLELEESLAEFLGQEAAIVFPMGFATNALNIPILVDKDCCVISDELNHVSLILGIRLSGADTRRFKHNNVESLERELIKAITEGHSKTKRKFK-KILVVVEGVYSMEGSIVRLPEILELKKKYKFYIYLDEAHSIGALGKGGRGVVDYFNLNPHEVDIQMGTFTKSFASSGGYISGSRNLIHYVREKSHSTIYGGTMSGPICQQILSAMAIIGGKMGGSLGAERIRQL-----AWNTTYFRAALHRMGLIVFGNKNSPVIPVIVYTIPKVVAFHRE----------CMRRGIGTVIVGY 1404
            RI     D  N GS+NYLGF ++  +  +   KS+ ++G+    PR   G    HL+LE+ +A+F+G E AIV+  GF+T A  IP    +   +  DE  + ++  G+  S +    FKHN+VE LER LI+         K+  K +  +V EG+Y   G I  LP+++ L++KYK  +++DE+ S G LG+GG GV ++FN++  EVD+       S A+ GG+  GS  +  + R      I+  ++   + Q  +SA+             ER  Q+     A + T  +  L    L + G++ SPV    +Y       F +E          C+ RG+  V   Y
Sbjct:   88 RIQVDGHDCLNLGSHNYLGFLEDQEILEEAC-KSLRKYGVGSCGPRGFYGTMDVHLDLEDRIAKFMGLEEAIVYSYGFSTVASAIPAYAKRGDLIFVDEAVNFAIQKGLDASRSTIVFFKHNDVEDLERLLIEQEKRDQKNPKKAAKTRRFLVAEGIYMNTGEICPLPDLVALRQKYKLRLFIDESISFGTLGQGGHGVTEHFNVDRDEVDLISAGMEGSMATVGGFCVGSHFIAEHQRLSGLGYIFSASLPPMLTQAAISALDRF----------EREPQIFEQLQAKSKTLHQKFLRFSKLTLRGDEVSPVKH--LYLAQPAENFDKELKLLTELADKCIARGVAVVQAAY 427
[Close]
BLAST of Serine palmitoyltransferase 2 vs. Ensembl Zebrafish
Match: sptlc2b (serine palmitoyltransferase, long chain base subunit 2b [Source:ZFIN;Acc:ZDB-GENE-080305-8])

HSP 1 Score: 555.829 bits (1431), Expect = 0.000e+0
Identity = 266/483 (55.07%), Postives = 346/483 (71.64%), Query Frame = 1 
Query:   88 FFEQFEKASLFNSLITYLYFFILKCMGKLRDFMRNYGLEKNRLAVDSTKNKGFAPLYLDFEAFYTRNVYRRVCDCVNKPICSAPGGSLKAMNRVSDDHNWTFRILDST-SDIYNFGSYNYLGFAQNDGLCTDYVEKSINEFGLSVGSPRQEVGNTLYHLELEESLAEFLGQEAAIVFPMGFATNALNIPILVDKDCCVISDELNHVSLILGIRLSGADTRRFKHNNVESLERELIKAITEGHSKTKRKFKKILVVVEGVYSMEGSIVRLPEILELKKKYKFYIYLDEAHSIGALGKGGRGVVDYFNLNPHEVDIQMGTFTKSFASSGGYISGSRNLIHYVREKSHSTIYGGTMSGPICQQILSAMAIIGGKMGGSLGAERIRQLAWNTTYFRAALHRMGLIVFGNKNSPVIPVIVYTIPKVVAFHRECMRRGIGTVIVGYPACNLKLARIRFCISAAHTKRSLDYTLSIVDEIATHLRFKYSR 1533
            F E FE+  L  +++TY+ + IL   G LRDF+R++  EK  LA +  + K F PLY DFE FYTRN+Y R+ D  N+PICS PG  +  + RV+ D+NWTF        D+ N GSYNYLGFA+N G C D    S  ++G+ V S RQE+GN   H ELE+ +A FLG E+++VF MGFATN++NIP L  K C ++SDELNH SL+LG RLSG+  R FKHNN++SLE+ L  AI  G  +T R +KKIL+VVEG+YSMEGSIVRLPEI+ LKKKYK Y+YLDEAHSIGALG  GRGVVDYF L+P +VDI MGTFTKSF ++GGYI G + LI Y+R  SHS +Y  +MS P+ QQI+++M  I G+ G +LG ER+RQL+ NTTYFR  LH MG I++GN +SPV+P+++Y   K+ AF RE ++R IGTV+VG+PA  +  +R RFC+SAAHT+  LD  L+ + E+   L+ KYSR
Sbjct:   58 FVESFEETPLLVAVLTYMGYGILTIFGYLRDFLRDWKFEKCHLAREREEQKDFVPLYQDFENFYTRNLYMRIRDNWNRPICSVPGAKMDLVERVTPDYNWTFEHTGKVLKDVINMGSYNYLGFAENSGTCADAAAYSTVKYGVGVSSTRQEIGNLDKHEELEKLVARFLGVESSMVFGMGFATNSMNIPALTGKGCLILSDELNHASLVLGARLSGSTIRVFKHNNMQSLEKMLRDAIVHGQPRTHRPWKKILIVVEGIYSMEGSIVRLPEIIALKKKYKAYLYLDEAHSIGALGTRGRGVVDYFGLDPSDVDIMMGTFTKSFGAAGGYIGGKKELIDYLRLHSHSAVYATSMSPPVTQQIITSMKCIMGEDGTTLGQERLRQLSENTTYFRRRLHEMGFIIYGNNDSPVVPLMLYMPAKIGAFGREMLKRNIGTVVVGFPATPIIESRARFCVSAAHTREMLDTALNAISEVGDLLQLKYSR 540
[Close]
BLAST of Serine palmitoyltransferase 2 vs. Ensembl Zebrafish
Match: sptlc2a (serine palmitoyltransferase, long chain base subunit 2a [Source:ZFIN;Acc:ZDB-GENE-050522-23])

HSP 1 Score: 536.184 bits (1380), Expect = 0.000e+0
Identity = 255/486 (52.47%), Postives = 341/486 (70.16%), Query Frame = 1 
Query:   88 FFEQFEKASLFNSLITYLYFFILKCMGKLRDFMRNYGLEKNRLAVDSTKNKGFAPLYLDFEAFYTRNVYRRVCDCVNKPICSAPGGSLKAMNRVSDDHNWTFRILDST-SDIYNFGSYNYLGFAQNDGLCTDYVEKSINEFGLSVGSPRQEVGNTLYHLELEESLAEFLGQEAAIVFPMGFATNALNIPILVDKDCCVISDELNHVSLILGIRLSGADTRRFKHNNVESLERELIKAITEGHSKTKRKFKKILVVVEGVYSMEGSIVRLPEILELKKKYKFYIYLDEAHSIGALGKGGRGVVDYFNLNPHEVDIQMGTFTKSFASSGGYISGSRNLIHYVREKSHSTIYGGTMSGPICQQILSAMAIIGGKMGGSLGAERIRQLAWNTTYFRAALHRMGLIVFGNKNSPVIPVIVYTIPKVVAFHRECMRRGIGTVIVGYPACNLKLARIRFCISAAHTKRSLDYTLSIVDEIATHLRFKYSRLPV 1542
            F E FE+  +  +++TY+ + IL   G LRDFMR + +EK  +A +  + K F PLY DFE FYTRN+Y R+ D  N+PICS PG     + R S+D+NWTF        D+ N GSYNYLGFA+N G C     +   +FG+ V S RQE+GN   H +LE+ +A FL  E+A+ F MGFATN++NIP L  K C ++SDELNH SL+LG RLSG+  R FKHNN++SLE+ L  AI  G  +T R +KKIL++VEG+YSMEGSI+RLPE++ LKKKYK Y+YLDEAHSIGALG GGRGVV+YF L+P +VDI MGTFTKSF ++GGYI G ++LI Y+R  SHS +Y  +MS P+ +QI+++M  I G+ G ++G  RI++LA NT YFR  L  MG I++GN +SPV+P+++Y   K+ AF RE ++R IG V+VG+PA  +  +R RFCISAAH+K  LD  L ++ E+   L+ KYSR  V
Sbjct:   55 FIESFEETPMLVAVLTYMGYGILTIFGYLRDFMREWKIEKCHIAREREEQKDFVPLYQDFENFYTRNLYMRIRDSWNRPICSVPGAKFDLVERSSNDYNWTFEYTGRVVKDVINLGSYNYLGFAENTGSCATAAGEVTVKFGVGVASTRQEMGNLDRHEKLEKLVASFLRVESAMAFGMGFATNSMNIPALAGKGCLILSDELNHASLVLGARLSGSTIRVFKHNNMQSLEKLLRDAIVHGQPRTHRPWKKILILVEGIYSMEGSIIRLPEVIALKKKYKAYLYLDEAHSIGALGPGGRGVVEYFGLDPRDVDIMMGTFTKSFGAAGGYIGGRKDLIDYLRTHSHSAVYASSMSAPVVEQIITSMKCIMGEDGTTIGRSRIQRLAENTVYFRRRLREMGFIIYGNNDSPVVPMMLYMPAKIGAFGREMLKRNIGVVVVGFPATPIIESRARFCISAAHSKEMLDRALDVISEVGDLLQLKYSRHKV 540
[Close]
BLAST of Serine palmitoyltransferase 2 vs. Ensembl Zebrafish
Match: sptlc3 (serine palmitoyltransferase, long chain base subunit 3 [Source:ZFIN;Acc:ZDB-GENE-041210-281])

HSP 1 Score: 524.628 bits (1350), Expect = 0.000e+0
Identity = 256/485 (52.78%), Postives = 342/485 (70.52%), Query Frame = 1 
Query:   94 EQFEKASLFNSLITYLYFFILKCMGKLRDFMRNYGLEKNRLAVDSTKNKGFAPLYLDFEAFYTRNVYRRVCDCVNKPICSAPGGSLKAMNRVSDDHNWTFRILDST-SDIYNFGSYNYLGFAQNDGLCTDYVEKSINEFGLSVGSPRQEVGNTLYHLELEESLAEFLGQEAAIVFPMGFATNALNIPILVDKDCCVISDELNHVSLILGIRLSGADTRRFKHNNVESLERELIKAITEGHSKTKRKFKKILVVVEGVYSMEGSIVRLPEILELKKKYKFYIYLDEAHSIGALGKGGRGVVDYFNLNPHEVDIQMGTFTKSFASSGGYISGSRNLIHYVREKSHSTIYGGTMSGPICQQILSAMAIIGGKMGGSLGAERIRQLAWNTTYFRAALHRMGLIVFGNKNSPVIPVIVYTIPKVVAFHRECMRRGIGTVIVGYPACNLKLARIRFCISAAHTKRSLDYTLSIVDEIATHLRFKYSRLPVP 1545
            + FE+A ++ +++TY+ + I+   G  RDF+R  GLEK   A +  + K F PLY DFE FY RN+Y RV D  N+PICS PG     M RVSDD+NWTFR+   T  ++ N GSYNYLGFA+N+      V +   ++G+ V S RQE+GN   H ELE  +A+FLG E+A+ F MGFATN++NIP LV K C ++SDELNH SLILG RLSGA  R FKHNN++SLE+ L +AI  G  +T R +KKIL++VEG+YSMEGS+VRLPEI+ LKKKYK Y+YLDEAHSIGA+G  GRGV ++F ++P E+D+ MGTFTKSF ++GGYI+G + L+ Y+R  SHS +Y   MS P+ +QI+ A+  I G  G + G  R+RQLA NT YFR+ L  MG I++GNK+SPVIP+++Y   KV AF R  ++R IG V+VG+PA  +  AR RFC+SAAHT+  L+  L  +DE+  ++R K+SR   P
Sbjct:   54 DSFEEAPMYVAVLTYMGYGIVILFGYFRDFLRAVGLEKCHQAQEREEQKDFVPLYQDFENFYKRNLYMRVRDNWNRPICSLPGPVFDLMERVSDDYNWTFRLTGRTIENVINMGSYNYLGFAENNVDFLKTVAEKTRQYGVGVCSTRQELGNFSIHEELEHLVADFLGVESAMAFGMGFATNSMNIPALVGKGCLILSDELNHTSLILGARLSGATIRVFKHNNMQSLEKLLKEAICSGQPRTHRSWKKILIMVEGIYSMEGSLVRLPEIIALKKKYKAYLYLDEAHSIGAVGPTGRGVTEHFGVDPKEIDVLMGTFTKSFGATGGYIAGKKELVDYLRCHSHSAVYATAMSPPVVEQIIRAIKCIMGVDGTTEGQRRVRQLAENTHYFRSRLKEMGFIIYGNKDSPVIPLLLYQPGKVGAFSRAMLKRKIGVVVVGFPATTITEARARFCVSAAHTRDMLNKVLQSLDELGDYIRVKFSRHRRP 538
[Close]
BLAST of Serine palmitoyltransferase 2 vs. Ensembl Zebrafish
Match: sptlc3 (serine palmitoyltransferase, long chain base subunit 3 [Source:ZFIN;Acc:ZDB-GENE-041210-281])

HSP 1 Score: 524.628 bits (1350), Expect = 0.000e+0
Identity = 256/485 (52.78%), Postives = 342/485 (70.52%), Query Frame = 1 
Query:   94 EQFEKASLFNSLITYLYFFILKCMGKLRDFMRNYGLEKNRLAVDSTKNKGFAPLYLDFEAFYTRNVYRRVCDCVNKPICSAPGGSLKAMNRVSDDHNWTFRILDST-SDIYNFGSYNYLGFAQNDGLCTDYVEKSINEFGLSVGSPRQEVGNTLYHLELEESLAEFLGQEAAIVFPMGFATNALNIPILVDKDCCVISDELNHVSLILGIRLSGADTRRFKHNNVESLERELIKAITEGHSKTKRKFKKILVVVEGVYSMEGSIVRLPEILELKKKYKFYIYLDEAHSIGALGKGGRGVVDYFNLNPHEVDIQMGTFTKSFASSGGYISGSRNLIHYVREKSHSTIYGGTMSGPICQQILSAMAIIGGKMGGSLGAERIRQLAWNTTYFRAALHRMGLIVFGNKNSPVIPVIVYTIPKVVAFHRECMRRGIGTVIVGYPACNLKLARIRFCISAAHTKRSLDYTLSIVDEIATHLRFKYSRLPVP 1545
            + FE+A ++ +++TY+ + I+   G  RDF+R  GLEK   A +  + K F PLY DFE FY RN+Y RV D  N+PICS PG     M RVSDD+NWTFR+   T  ++ N GSYNYLGFA+N+      V +   ++G+ V S RQE+GN   H ELE  +A+FLG E+A+ F MGFATN++NIP LV K C ++SDELNH SLILG RLSGA  R FKHNN++SLE+ L +AI  G  +T R +KKIL++VEG+YSMEGS+VRLPEI+ LKKKYK Y+YLDEAHSIGA+G  GRGV ++F ++P E+D+ MGTFTKSF ++GGYI+G + L+ Y+R  SHS +Y   MS P+ +QI+ A+  I G  G + G  R+RQLA NT YFR+ L  MG I++GNK+SPVIP+++Y   KV AF R  ++R IG V+VG+PA  +  AR RFC+SAAHT+  L+  L  +DE+  ++R K+SR   P
Sbjct:   54 DSFEEAPMYVAVLTYMGYGIVILFGYFRDFLRAVGLEKCHQAQEREEQKDFVPLYQDFENFYKRNLYMRVRDNWNRPICSLPGPVFDLMERVSDDYNWTFRLTGRTIENVINMGSYNYLGFAENNVDFLKTVAEKTRQYGVGVCSTRQELGNFSIHEELEHLVADFLGVESAMAFGMGFATNSMNIPALVGKGCLILSDELNHTSLILGARLSGATIRVFKHNNMQSLEKLLKEAICSGQPRTHRSWKKILIMVEGIYSMEGSLVRLPEIIALKKKYKAYLYLDEAHSIGAVGPTGRGVTEHFGVDPKEIDVLMGTFTKSFGATGGYIAGKKELVDYLRCHSHSAVYATAMSPPVVEQIIRAIKCIMGVDGTTEGQRRVRQLAENTHYFRSRLKEMGFIIYGNKDSPVIPLLLYQPGKVGAFSRAMLKRKIGVVVVGFPATTITEARARFCVSAAHTRDMLNKVLQSLDELGDYIRVKFSRHRRP 538
[Close]
BLAST of Serine palmitoyltransferase 2 vs. Ensembl Zebrafish
Match: sptlc2a (serine palmitoyltransferase, long chain base subunit 2a [Source:ZFIN;Acc:ZDB-GENE-050522-23])

HSP 1 Score: 146.747 bits (369), Expect = 6.992e-40
Identity = 71/158 (44.94%), Postives = 95/158 (60.13%), Query Frame = 1 
Query:   88 FFEQFEKASLFNSLITYLYFFILKCMGKLRDFMRNYGLEKNRLAVDSTKNKGFAPLYLDFEAFYTRNVYRRVCDCVNKPICSAPGGSLKAMNRVSDDHNWTFRILDS-TSDIYNFGSYNYLGFAQNDGLCTDYVEKSINEFGLSVGSPRQEVGNTLYH 558
            F E FE+  +  +++TY+ + IL   G LRDFMR + +EK  +A +  + K F PLY DFE FYTRN+Y R+ D  N+PICS PG     + R S+D+NWTF        D+ N GSYNYLGFA+N G C     +   +FG+ V S RQE+    YH
Sbjct:   55 FIESFEETPMLVAVLTYMGYGILTIFGYLRDFMREWKIEKCHIAREREEQKDFVPLYQDFENFYTRNLYMRIRDSWNRPICSVPGAKFDLVERSSNDYNWTFEYTGRVVKDVINLGSYNYLGFAENTGSCATAAGEVTVKFGVGVASTRQEMDFHSYH 212
[Close]
BLAST of Serine palmitoyltransferase 2 vs. Ensembl Xenopus
Match: wdr93 (WD repeat domain 93 [Source:Xenbase;Acc:XB-GENE-6462910])

HSP 1 Score: 554.673 bits (1428), Expect = 0.000e+0
Identity = 266/483 (55.07%), Postives = 344/483 (71.22%), Query Frame = 1 
Query:   88 FFEQFEKASLFNSLITYLYFFILKCMGKLRDFMRNYGLEKNRLAVDSTKNKGFAPLYLDFEAFYTRNVYRRVCDCVNKPICSAPGGSLKAMNRVSDDHNWTFRILDST-SDIYNFGSYNYLGFAQNDGLCTDYVEKSINEFGLSVGSPRQEVGNTLYHLELEESLAEFLGQEAAIVFPMGFATNALNIPILVDKDCCVISDELNHVSLILGIRLSGADTRRFKHNNVESLERELIKAITEGHSKTKRKFKKILVVVEGVYSMEGSIVRLPEILELKKKYKFYIYLDEAHSIGALGKGGRGVVDYFNLNPHEVDIQMGTFTKSFASSGGYISGSRNLIHYVREKSHSTIYGGTMSGPICQQILSAMAIIGGKMGGSLGAERIRQLAWNTTYFRAALHRMGLIVFGNKNSPVIPVIVYTIPKVVAFHRECMRRGIGTVIVGYPACNLKLARIRFCISAAHTKRSLDYTLSIVDEIATHLRFKYSR 1533
            F E FE+  +  +++TY+ + IL   G LRDF+R + +EK  +A +  + K F PLY DFE FYTRN+Y R+ D  N+P+CS PG  +  M R +DD+NWTF+        + N GSYNYLGFAQN G C D   KS+N++G  + S RQE+GN   H ELE  +A FLG EAA+ + MGFATN++NIP LV K C ++SDELNH SL+LG RLSGA  R FKHNN++SLE+ L  AI +G  +T R +KKIL+VVEG+YSMEGSIVRLPE++ LKKKYK Y+YLDEAHSIGALG  GRGVVDYF L+P +VDI MGTFTKSF S+GGYI GS+ LI Y+R  SHS  Y  +MS P+ QQI+S+M  I G+ G +LG +R+ QLA NT YFR  L  MG I++GN +SPV+P+++Y   K+ AF RE ++R IG V+VG+PA  +  +R RFC+SAAHTK  LD  L  ++E+   L+ KYSR
Sbjct:   52 FNEAFEETPMLVAVLTYMGYGILTLFGYLRDFLRTWKIEKCHIATERVEQKDFVPLYQDFENFYTRNLYMRIRDNWNRPVCSVPGERIDVMERFTDDYNWTFKFTGRVIKGVINMGSYNYLGFAQNTGFCADASAKSLNQYGAGMCSTRQEIGNMEKHEELEHLVARFLGVEAAMTYGMGFATNSMNIPALVGKGCLILSDELNHSSLVLGARLSGATIRIFKHNNMQSLEKLLRDAIVQGQPRTHRPWKKILIVVEGIYSMEGSIVRLPEVIALKKKYKAYLYLDEAHSIGALGPNGRGVVDYFGLDPRDVDIMMGTFTKSFGSAGGYIGGSKVLIEYLRAHSHSAAYATSMSLPVVQQIISSMKCIMGEDGTTLGQKRVEQLAENTRYFRRRLTEMGFIIYGNSDSPVVPLMLYMPAKIGAFGREMLKRNIGVVVVGFPATPIIESRARFCVSAAHTKEMLDAALREINEVGDLLQLKYSR 534
[Close]
BLAST of Serine palmitoyltransferase 2 vs. Ensembl Xenopus
Match: wdr93 (WD repeat domain 93 [Source:Xenbase;Acc:XB-GENE-6462910])

HSP 1 Score: 554.288 bits (1427), Expect = 0.000e+0
Identity = 266/483 (55.07%), Postives = 344/483 (71.22%), Query Frame = 1 
Query:   88 FFEQFEKASLFNSLITYLYFFILKCMGKLRDFMRNYGLEKNRLAVDSTKNKGFAPLYLDFEAFYTRNVYRRVCDCVNKPICSAPGGSLKAMNRVSDDHNWTFRILDST-SDIYNFGSYNYLGFAQNDGLCTDYVEKSINEFGLSVGSPRQEVGNTLYHLELEESLAEFLGQEAAIVFPMGFATNALNIPILVDKDCCVISDELNHVSLILGIRLSGADTRRFKHNNVESLERELIKAITEGHSKTKRKFKKILVVVEGVYSMEGSIVRLPEILELKKKYKFYIYLDEAHSIGALGKGGRGVVDYFNLNPHEVDIQMGTFTKSFASSGGYISGSRNLIHYVREKSHSTIYGGTMSGPICQQILSAMAIIGGKMGGSLGAERIRQLAWNTTYFRAALHRMGLIVFGNKNSPVIPVIVYTIPKVVAFHRECMRRGIGTVIVGYPACNLKLARIRFCISAAHTKRSLDYTLSIVDEIATHLRFKYSR 1533
            F E FE+  +  +++TY+ + IL   G LRDF+R + +EK  +A +  + K F PLY DFE FYTRN+Y R+ D  N+P+CS PG  +  M R +DD+NWTF+        + N GSYNYLGFAQN G C D   KS+N++G  + S RQE+GN   H ELE  +A FLG EAA+ + MGFATN++NIP LV K C ++SDELNH SL+LG RLSGA  R FKHNN++SLE+ L  AI +G  +T R +KKIL+VVEG+YSMEGSIVRLPE++ LKKKYK Y+YLDEAHSIGALG  GRGVVDYF L+P +VDI MGTFTKSF S+GGYI GS+ LI Y+R  SHS  Y  +MS P+ QQI+S+M  I G+ G +LG +R+ QLA NT YFR  L  MG I++GN +SPV+P+++Y   K+ AF RE ++R IG V+VG+PA  +  +R RFC+SAAHTK  LD  L  ++E+   L+ KYSR
Sbjct:   29 FNEAFEETPMLVAVLTYMGYGILTLFGYLRDFLRTWKIEKCHIATERVEQKDFVPLYQDFENFYTRNLYMRIRDNWNRPVCSVPGERIDVMERFTDDYNWTFKFTGRVIKGVINMGSYNYLGFAQNTGFCADASAKSLNQYGAGMCSTRQEIGNMEKHEELEHLVARFLGVEAAMTYGMGFATNSMNIPALVGKGCLILSDELNHSSLVLGARLSGATIRIFKHNNMQSLEKLLRDAIVQGQPRTHRPWKKILIVVEGIYSMEGSIVRLPEVIALKKKYKAYLYLDEAHSIGALGPNGRGVVDYFGLDPRDVDIMMGTFTKSFGSAGGYIGGSKVLIEYLRAHSHSAAYATSMSLPVVQQIISSMKCIMGEDGTTLGQKRVEQLAENTRYFRRRLTEMGFIIYGNSDSPVVPLMLYMPAKIGAFGREMLKRNIGVVVVGFPATPIIESRARFCVSAAHTKEMLDAALREINEVGDLLQLKYSR 511
[Close]
BLAST of Serine palmitoyltransferase 2 vs. Ensembl Xenopus
Match: wdr93 (WD repeat domain 93 [Source:Xenbase;Acc:XB-GENE-6462910])

HSP 1 Score: 554.288 bits (1427), Expect = 0.000e+0
Identity = 266/483 (55.07%), Postives = 344/483 (71.22%), Query Frame = 1 
Query:   88 FFEQFEKASLFNSLITYLYFFILKCMGKLRDFMRNYGLEKNRLAVDSTKNKGFAPLYLDFEAFYTRNVYRRVCDCVNKPICSAPGGSLKAMNRVSDDHNWTFRILDST-SDIYNFGSYNYLGFAQNDGLCTDYVEKSINEFGLSVGSPRQEVGNTLYHLELEESLAEFLGQEAAIVFPMGFATNALNIPILVDKDCCVISDELNHVSLILGIRLSGADTRRFKHNNVESLERELIKAITEGHSKTKRKFKKILVVVEGVYSMEGSIVRLPEILELKKKYKFYIYLDEAHSIGALGKGGRGVVDYFNLNPHEVDIQMGTFTKSFASSGGYISGSRNLIHYVREKSHSTIYGGTMSGPICQQILSAMAIIGGKMGGSLGAERIRQLAWNTTYFRAALHRMGLIVFGNKNSPVIPVIVYTIPKVVAFHRECMRRGIGTVIVGYPACNLKLARIRFCISAAHTKRSLDYTLSIVDEIATHLRFKYSR 1533
            F E FE+  +  +++TY+ + IL   G LRDF+R + +EK  +A +  + K F PLY DFE FYTRN+Y R+ D  N+P+CS PG  +  M R +DD+NWTF+        + N GSYNYLGFAQN G C D   KS+N++G  + S RQE+GN   H ELE  +A FLG EAA+ + MGFATN++NIP LV K C ++SDELNH SL+LG RLSGA  R FKHNN++SLE+ L  AI +G  +T R +KKIL+VVEG+YSMEGSIVRLPE++ LKKKYK Y+YLDEAHSIGALG  GRGVVDYF L+P +VDI MGTFTKSF S+GGYI GS+ LI Y+R  SHS  Y  +MS P+ QQI+S+M  I G+ G +LG +R+ QLA NT YFR  L  MG I++GN +SPV+P+++Y   K+ AF RE ++R IG V+VG+PA  +  +R RFC+SAAHTK  LD  L  ++E+   L+ KYSR
Sbjct:    5 FNEAFEETPMLVAVLTYMGYGILTLFGYLRDFLRTWKIEKCHIATERVEQKDFVPLYQDFENFYTRNLYMRIRDNWNRPVCSVPGERIDVMERFTDDYNWTFKFTGRVIKGVINMGSYNYLGFAQNTGFCADASAKSLNQYGAGMCSTRQEIGNMEKHEELEHLVARFLGVEAAMTYGMGFATNSMNIPALVGKGCLILSDELNHSSLVLGARLSGATIRIFKHNNMQSLEKLLRDAIVQGQPRTHRPWKKILIVVEGIYSMEGSIVRLPEVIALKKKYKAYLYLDEAHSIGALGPNGRGVVDYFGLDPRDVDIMMGTFTKSFGSAGGYIGGSKVLIEYLRAHSHSAAYATSMSLPVVQQIISSMKCIMGEDGTTLGQKRVEQLAENTRYFRRRLTEMGFIIYGNSDSPVVPLMLYMPAKIGAFGREMLKRNIGVVVVGFPATPIIESRARFCVSAAHTKEMLDAALREINEVGDLLQLKYSR 487
[Close]
BLAST of Serine palmitoyltransferase 2 vs. Ensembl Xenopus
Match: wdr93 (WD repeat domain 93 [Source:Xenbase;Acc:XB-GENE-6462910])

HSP 1 Score: 554.288 bits (1427), Expect = 0.000e+0
Identity = 266/483 (55.07%), Postives = 344/483 (71.22%), Query Frame = 1 
Query:   88 FFEQFEKASLFNSLITYLYFFILKCMGKLRDFMRNYGLEKNRLAVDSTKNKGFAPLYLDFEAFYTRNVYRRVCDCVNKPICSAPGGSLKAMNRVSDDHNWTFRILDST-SDIYNFGSYNYLGFAQNDGLCTDYVEKSINEFGLSVGSPRQEVGNTLYHLELEESLAEFLGQEAAIVFPMGFATNALNIPILVDKDCCVISDELNHVSLILGIRLSGADTRRFKHNNVESLERELIKAITEGHSKTKRKFKKILVVVEGVYSMEGSIVRLPEILELKKKYKFYIYLDEAHSIGALGKGGRGVVDYFNLNPHEVDIQMGTFTKSFASSGGYISGSRNLIHYVREKSHSTIYGGTMSGPICQQILSAMAIIGGKMGGSLGAERIRQLAWNTTYFRAALHRMGLIVFGNKNSPVIPVIVYTIPKVVAFHRECMRRGIGTVIVGYPACNLKLARIRFCISAAHTKRSLDYTLSIVDEIATHLRFKYSR 1533
            F E FE+  +  +++TY+ + IL   G LRDF+R + +EK  +A +  + K F PLY DFE FYTRN+Y R+ D  N+P+CS PG  +  M R +DD+NWTF+        + N GSYNYLGFAQN G C D   KS+N++G  + S RQE+GN   H ELE  +A FLG EAA+ + MGFATN++NIP LV K C ++SDELNH SL+LG RLSGA  R FKHNN++SLE+ L  AI +G  +T R +KKIL+VVEG+YSMEGSIVRLPE++ LKKKYK Y+YLDEAHSIGALG  GRGVVDYF L+P +VDI MGTFTKSF S+GGYI GS+ LI Y+R  SHS  Y  +MS P+ QQI+S+M  I G+ G +LG +R+ QLA NT YFR  L  MG I++GN +SPV+P+++Y   K+ AF RE ++R IG V+VG+PA  +  +R RFC+SAAHTK  LD  L  ++E+   L+ KYSR
Sbjct:    9 FNEAFEETPMLVAVLTYMGYGILTLFGYLRDFLRTWKIEKCHIATERVEQKDFVPLYQDFENFYTRNLYMRIRDNWNRPVCSVPGERIDVMERFTDDYNWTFKFTGRVIKGVINMGSYNYLGFAQNTGFCADASAKSLNQYGAGMCSTRQEIGNMEKHEELEHLVARFLGVEAAMTYGMGFATNSMNIPALVGKGCLILSDELNHSSLVLGARLSGATIRIFKHNNMQSLEKLLRDAIVQGQPRTHRPWKKILIVVEGIYSMEGSIVRLPEVIALKKKYKAYLYLDEAHSIGALGPNGRGVVDYFGLDPRDVDIMMGTFTKSFGSAGGYIGGSKVLIEYLRAHSHSAAYATSMSLPVVQQIISSMKCIMGEDGTTLGQKRVEQLAENTRYFRRRLTEMGFIIYGNSDSPVVPLMLYMPAKIGAFGREMLKRNIGVVVVGFPATPIIESRARFCVSAAHTKEMLDAALREINEVGDLLQLKYSR 491
[Close]
BLAST of Serine palmitoyltransferase 2 vs. Ensembl Xenopus
Match: wdr93 (WD repeat domain 93 [Source:Xenbase;Acc:XB-GENE-6462910])

HSP 1 Score: 554.288 bits (1427), Expect = 0.000e+0
Identity = 266/483 (55.07%), Postives = 344/483 (71.22%), Query Frame = 1 
Query:   88 FFEQFEKASLFNSLITYLYFFILKCMGKLRDFMRNYGLEKNRLAVDSTKNKGFAPLYLDFEAFYTRNVYRRVCDCVNKPICSAPGGSLKAMNRVSDDHNWTFRILDST-SDIYNFGSYNYLGFAQNDGLCTDYVEKSINEFGLSVGSPRQEVGNTLYHLELEESLAEFLGQEAAIVFPMGFATNALNIPILVDKDCCVISDELNHVSLILGIRLSGADTRRFKHNNVESLERELIKAITEGHSKTKRKFKKILVVVEGVYSMEGSIVRLPEILELKKKYKFYIYLDEAHSIGALGKGGRGVVDYFNLNPHEVDIQMGTFTKSFASSGGYISGSRNLIHYVREKSHSTIYGGTMSGPICQQILSAMAIIGGKMGGSLGAERIRQLAWNTTYFRAALHRMGLIVFGNKNSPVIPVIVYTIPKVVAFHRECMRRGIGTVIVGYPACNLKLARIRFCISAAHTKRSLDYTLSIVDEIATHLRFKYSR 1533
            F E FE+  +  +++TY+ + IL   G LRDF+R + +EK  +A +  + K F PLY DFE FYTRN+Y R+ D  N+P+CS PG  +  M R +DD+NWTF+        + N GSYNYLGFAQN G C D   KS+N++G  + S RQE+GN   H ELE  +A FLG EAA+ + MGFATN++NIP LV K C ++SDELNH SL+LG RLSGA  R FKHNN++SLE+ L  AI +G  +T R +KKIL+VVEG+YSMEGSIVRLPE++ LKKKYK Y+YLDEAHSIGALG  GRGVVDYF L+P +VDI MGTFTKSF S+GGYI GS+ LI Y+R  SHS  Y  +MS P+ QQI+S+M  I G+ G +LG +R+ QLA NT YFR  L  MG I++GN +SPV+P+++Y   K+ AF RE ++R IG V+VG+PA  +  +R RFC+SAAHTK  LD  L  ++E+   L+ KYSR
Sbjct:    4 FNEAFEETPMLVAVLTYMGYGILTLFGYLRDFLRTWKIEKCHIATERVEQKDFVPLYQDFENFYTRNLYMRIRDNWNRPVCSVPGERIDVMERFTDDYNWTFKFTGRVIKGVINMGSYNYLGFAQNTGFCADASAKSLNQYGAGMCSTRQEIGNMEKHEELEHLVARFLGVEAAMTYGMGFATNSMNIPALVGKGCLILSDELNHSSLVLGARLSGATIRIFKHNNMQSLEKLLRDAIVQGQPRTHRPWKKILIVVEGIYSMEGSIVRLPEVIALKKKYKAYLYLDEAHSIGALGPNGRGVVDYFGLDPRDVDIMMGTFTKSFGSAGGYIGGSKVLIEYLRAHSHSAAYATSMSLPVVQQIISSMKCIMGEDGTTLGQKRVEQLAENTRYFRRRLTEMGFIIYGNSDSPVVPLMLYMPAKIGAFGREMLKRNIGVVVVGFPATPIIESRARFCVSAAHTKEMLDAALREINEVGDLLQLKYSR 486
[Close]
BLAST of Serine palmitoyltransferase 2 vs. Ensembl Mouse
Match: Sptlc2 (serine palmitoyltransferase, long chain base subunit 2 [Source:MGI Symbol;Acc:MGI:108074])

HSP 1 Score: 537.339 bits (1383), Expect = 0.000e+0
Identity = 261/499 (52.30%), Postives = 348/499 (69.74%), Query Frame = 1 
Query:   40 GHIKSIKQETKCKESEFFEQFEKASLFNSLITYLYFFILKCMGKLRDFMRNYGLEKNRLAVDSTKNKGFAPLYLDFEAFYTRNVYRRVCDCVNKPICSAPGGSLKAMNRVSDDHNWTFRILDST-SDIYNFGSYNYLGFAQNDGLCTDYVEKSINEFGLSVGSPRQEVGNTLYHLELEESLAEFLGQEAAIVFPMGFATNALNIPILVDKDCCVISDELNHVSLILGIRLSGADTRRFKHNNVESLERELIKAITEGHSKTKRKFKKILVVVEGVYSMEGSIVRLPEILELKKKYKFYIYLDEAHSIGALGKGGRGVVDYFNLNPHEVDIQMGTFTKSFASSGGYISGSRNLIHYVREKSHSTIYGGTMSGPICQQILSAMAIIGGKMGGSLGAERIRQLAWNTTYFRAALHRMGLIVFGNKNSPVIPVIVYTIPKVVAFHRECMRRGIGTVIVGYPACNLKLARIRFCISAAHTKRSLDYTLSIVDEIATHLRFKYSR 1533
            G I  + +     +  F E FE+  +  +++TY+ + +L   G LRDF+R++ +EK   A +  + K F  LY DFE FYTRN+Y R+ D  N+PICS PG  +  M R S D+NW+F+   +    + N GSYNYLGFA+N G C +   + + E+G  V S RQE+GN   H ELE+ +A FLG EAA+ + MGFATN++NIP LV K C ++SDELNH SL+LG RLSGA  R FKHNN++SLE+ L  AI  G  +T+R +KKIL++VEG+YSMEGSIVRLPE++ LKKKYK Y+YLDEAHSIGALG  GRGVVDYF L+P +VD+ MGTFTKSF +SGGYI G + LI Y+R  SHS +Y  +MS P+ +QI+++M  I G+ G SLG E I+QLA NT YFR  L  MG I++GN++SPV+P+++Y   K+ AF RE ++R IG V+VG+PA  +  +R RFC+SAAHTK  LD  L  +DE+   L+ KYSR
Sbjct:   41 GQIHHVTENGGLYKRPFNEAFEETPMLVAVLTYVGYGVLTLFGYLRDFLRHWRIEKCHHATEREEQKDFVSLYQDFENFYTRNLYMRIRDNWNRPICSVPGAKVDIMERKSHDYNWSFKYTGNIIKGVINMGSYNYLGFARNTGSCQEAAAEVLKEYGAGVCSTRQEIGNLDKHEELEKLVARFLGVEAAMTYGMGFATNSMNIPALVGKGCLILSDELNHASLVLGARLSGATIRIFKHNNMQSLEKLLKDAIVYGQPRTRRPWKKILILVEGIYSMEGSIVRLPEVIALKKKYKAYLYLDEAHSIGALGPSGRGVVDYFGLDPEDVDVMMGTFTKSFGASGGYIGGKKELIDYLRTHSHSAVYATSMSPPVMEQIITSMKCIMGQDGTSLGKECIQQLAENTRYFRRRLKEMGFIIYGNEDSPVVPLMLYMPAKIGAFGREMLKRNIGVVVVGFPATPIIESRARFCLSAAHTKEILDTALKEIDEVGDLLQLKYSR 539
[Close]
BLAST of Serine palmitoyltransferase 2 vs. Ensembl Mouse
Match: Sptlc3 (serine palmitoyltransferase, long chain base subunit 3 [Source:MGI Symbol;Acc:MGI:2444678])

HSP 1 Score: 478.019 bits (1229), Expect = 1.263e-162
Identity = 243/500 (48.60%), Postives = 324/500 (64.80%), Query Frame = 1 
Query:   37 NGHIKSIKQETKC--KESEFFEQFEKASLFNSLITYLYFFILKCMGKLRDFMRNYGLEKNRLAVDSTKNKGFAPLYLDFEAFYTRNVYRRVCDCVNKPICSAPGGSLKAMNRVSDDHNWTFRILDST-SDIYNFGSYNYLGFAQNDGLCTDYVEKSINEFGLSVGSPRQEVGNTLYHLELEESLAEFLGQEAAIVFPMGFATNALNIPILVDKDCCVISDELNHVSLILGIRLSGADTRRFKHNNVESLERELIKAITEGHSKTKRKFKKILVVVEGVYSMEGSIVRLPEILELKKKYKFYIYLDEAHSIGALGKGGRGVVDYFNLNPHEVDIQMGTFTKSFASSGGYISGSRNLIHYVREKSHSTIYGGTMSGPICQQILSAMAIIGGKMGGSLGAERIRQLAWNTTYFRAALHRMGLIVFGNKNSPVIPVIVYTIPKVVAFHRECMRRGIGTVIVGYPACNLKLARIRFCISAAHTKRSLDYTLSIVDEIATHLRFKY 1527
            NG  K  +Q  K   ++   FE +++A L+  ++TY+ + I    G LRDFMRN+G+EK   AV+  + K F PLY DFE FY RN+Y R+ D  +  +CSAP   +  M +V+DD+NWTFR       +I N  SYNYLG A         V+ ++ ++G+ V S R E+G    H ELE+ +AEFL  EA + F MGFATNA+NIP+ V K C ++SDE NH S+ILG RLSGA  R FKHNN E+LE+ L +AI  G   T R +KKIL+VVEGVYSMEGSIV L +I+ LKKKYK Y+Y+DEAHSIG  G  GRGV + F L+P ++D+ MGTFTKSF+ SGGYI G + ++ Y+R +SHST Y  +MS  +  Q++ ++ I  G  G   G ERI+QL  N  YFR  L  MG I++GN  SPVIPV++Y   KV AF R  +++ I  V+VG+PA +L   R RF +S+AHT+  LD  L +VDE+   L  KY
Sbjct:   32 NGISKEAQQNRKAYAEDKPVFEPYQEAPLYVYVLTYMGYGIGILFGYLRDFMRNWGIEKCNAAVEREEQKDFVPLYQDFENFYKRNLYMRIRDSWSHTVCSAPEPYMNVMEKVTDDYNWTFRHTGKVIENIINMASYNYLGLAGKYDDSMVRVKDTLEKYGVGVASTRNEMGTLDIHKELEDLMAEFLNVEAVMSFGMGFATNAMNIPVFVGKGCLILSDEFNHTSVILGSRLSGAVIRPFKHNNAENLEKLLREAIIRGQPGTGRAWKKILIVVEGVYSMEGSIVNLAQIVALKKKYKAYLYIDEAHSIGCTGPTGRGVRELFGLDPEDIDVYMGTFTKSFSGSGGYIGGKKEIVDYLRMQSHSTTYATSMSPVVAAQLIRSLKITMGYEGNIGGMERIQQLKENIKYFRRRLKEMGFIIYGNDFSPVIPVLLYMPAKVSAFSRFLLKKKISVVVVGFPATSLPEGRARFSMSSAHTREMLDTVLEVVDELGDLLNVKY 531
[Close]
BLAST of Serine palmitoyltransferase 2 vs. Ensembl Mouse
Match: Sptlc3 (serine palmitoyltransferase, long chain base subunit 3 [Source:MGI Symbol;Acc:MGI:2444678])

HSP 1 Score: 478.019 bits (1229), Expect = 1.263e-162
Identity = 243/500 (48.60%), Postives = 324/500 (64.80%), Query Frame = 1 
Query:   37 NGHIKSIKQETKC--KESEFFEQFEKASLFNSLITYLYFFILKCMGKLRDFMRNYGLEKNRLAVDSTKNKGFAPLYLDFEAFYTRNVYRRVCDCVNKPICSAPGGSLKAMNRVSDDHNWTFRILDST-SDIYNFGSYNYLGFAQNDGLCTDYVEKSINEFGLSVGSPRQEVGNTLYHLELEESLAEFLGQEAAIVFPMGFATNALNIPILVDKDCCVISDELNHVSLILGIRLSGADTRRFKHNNVESLERELIKAITEGHSKTKRKFKKILVVVEGVYSMEGSIVRLPEILELKKKYKFYIYLDEAHSIGALGKGGRGVVDYFNLNPHEVDIQMGTFTKSFASSGGYISGSRNLIHYVREKSHSTIYGGTMSGPICQQILSAMAIIGGKMGGSLGAERIRQLAWNTTYFRAALHRMGLIVFGNKNSPVIPVIVYTIPKVVAFHRECMRRGIGTVIVGYPACNLKLARIRFCISAAHTKRSLDYTLSIVDEIATHLRFKY 1527
            NG  K  +Q  K   ++   FE +++A L+  ++TY+ + I    G LRDFMRN+G+EK   AV+  + K F PLY DFE FY RN+Y R+ D  +  +CSAP   +  M +V+DD+NWTFR       +I N  SYNYLG A         V+ ++ ++G+ V S R E+G    H ELE+ +AEFL  EA + F MGFATNA+NIP+ V K C ++SDE NH S+ILG RLSGA  R FKHNN E+LE+ L +AI  G   T R +KKIL+VVEGVYSMEGSIV L +I+ LKKKYK Y+Y+DEAHSIG  G  GRGV + F L+P ++D+ MGTFTKSF+ SGGYI G + ++ Y+R +SHST Y  +MS  +  Q++ ++ I  G  G   G ERI+QL  N  YFR  L  MG I++GN  SPVIPV++Y   KV AF R  +++ I  V+VG+PA +L   R RF +S+AHT+  LD  L +VDE+   L  KY
Sbjct:   32 NGISKEAQQNRKAYAEDKPVFEPYQEAPLYVYVLTYMGYGIGILFGYLRDFMRNWGIEKCNAAVEREEQKDFVPLYQDFENFYKRNLYMRIRDSWSHTVCSAPEPYMNVMEKVTDDYNWTFRHTGKVIENIINMASYNYLGLAGKYDDSMVRVKDTLEKYGVGVASTRNEMGTLDIHKELEDLMAEFLNVEAVMSFGMGFATNAMNIPVFVGKGCLILSDEFNHTSVILGSRLSGAVIRPFKHNNAENLEKLLREAIIRGQPGTGRAWKKILIVVEGVYSMEGSIVNLAQIVALKKKYKAYLYIDEAHSIGCTGPTGRGVRELFGLDPEDIDVYMGTFTKSFSGSGGYIGGKKEIVDYLRMQSHSTTYATSMSPVVAAQLIRSLKITMGYEGNIGGMERIQQLKENIKYFRRRLKEMGFIIYGNDFSPVIPVLLYMPAKVSAFSRFLLKKKISVVVVGFPATSLPEGRARFSMSSAHTREMLDTVLEVVDELGDLLNVKY 531
[Close]
BLAST of Serine palmitoyltransferase 2 vs. Ensembl Mouse
Match: Gcat (glycine C-acetyltransferase (2-amino-3-ketobutyrate-coenzyme A ligase) [Source:MGI Symbol;Acc:MGI:1349389])

HSP 1 Score: 153.295 bits (386), Expect = 2.044e-40
Identity = 108/388 (27.84%), Postives = 184/388 (47.42%), Query Frame = 1 
Query:  343 GSLKAMNRVSDDHNWTFRILDSTSDIYNFGSYNYLGFAQNDGLCTDYVEKSINEFGLSVGSPRQEVGNTLYHLELEESLAEFLGQEAAIVFPMGFATNALNIPILVDKDCCVISDELNHVSLILGIRLSGADTRRFKHNNVESLERELIKAITEGHSKTKRKFKKILVVVEGVYSMEGSIVRLPEILELKKKYKFYIYLDEAHSIGALGKGGRGVVDYFNLNPHEVDIQMGTFTKSF-ASSGGYISGSRNLIHYVREKSHSTIYGGTMSGPICQQILSAMAIIGGKMGGSLGAERIRQLAWNTTYFRAALHRMGLIVFGNKNSPVIPVIVYTIPKVVAFHRECMRRGIGTVIVGYPACNLKLARIRFCISAAHTKRSLDYTLSIVDEI 1503
            G+ K+   ++     + R+   +  I NF + NYLG + +  +    ++ ++ EFG  + S R   G    H  LE  +A F  +E AI++P  F  NA     L+  +  V+SDELNH S+I GIRL  A   R++H ++  LE +L         K  +K +  LV  +G +SM+G I  L +I  L  +Y   +++DE H+ G LG  GRG  +   +   +V I   T  K+   +SGGY +G   L+  +R++S   ++  ++   +      A+ ++            I+ +A  T  FR+ +   G  V G  + P+ PV++           + +++GI  +   YP      ARIR  ISA H++  +D  +    E+
Sbjct:   39 GTWKSERVITSRQGPSIRVDGISGGILNFCANNYLGLSSHPAVIQAGLQ-TLEEFGAGLSSTRFICGTQSIHKNLEAKIAHFHQREDAILYPSCFDANAGLFEALLTPEDAVLSDELNHASIIDGIRLCKAHKYRYRHLDMADLEAKL---------KEAQKHRLRLVATDGAFSMDGDIAPLQDICRLAAQYGALVFVDECHATGFLGPTGRGTDELLGVM-DQVTIINSTLGKALGGASGGYTTGPEPLVSLLRQRSRPYLFSNSLPPAVVGCASKALDLL------MESNAIIQSMAAKTRRFRSKMEAAGFTVSG-ADHPICPVMLGDARLSSQMADDMLKKGIFVIGFSYPVVPKGKARIRVQISAVHSEEDIDRCVEAFVEV 408
[Close]
BLAST of Serine palmitoyltransferase 2 vs. Ensembl Mouse
Match: Gcat (glycine C-acetyltransferase (2-amino-3-ketobutyrate-coenzyme A ligase) [Source:MGI Symbol;Acc:MGI:1349389])

HSP 1 Score: 135.576 bits (340), Expect = 2.101e-34
Identity = 94/330 (28.48%), Postives = 160/330 (48.48%), Query Frame = 1 
Query:  343 GSLKAMNRVSDDHNWTFRILDSTSDIYNFGSYNYLGFAQNDGLCTDYVEKSINEFGLSVGSPRQEVGNTLYHLELEESLAEFLGQEAAIVFPMGFATNALNIPILVDKDCCVISDELNHVSLILGIRLSGADTRRFKHNNVESLERELIKAITEGHSKTKRKFKKILVVVEGVYSMEGSIVRLPEILELKKKYKFYIYLDEAHSIGALGKGGRGVVDYFNLNPHEVDIQMGTFTKSF-ASSGGYISGSRNLIHYVREKSHSTIYGGTMSGPICQQILSAMAIIGGKMGGSLGAERIRQLAWNTTYFRAALHRMGLIVFGNKNSPVIPVIV 1329
            G+ K+   ++     + R+   +  I NF + NYLG + +  +    ++ ++ EFG  + S R   G    H  LE  +A F  +E AI++P  F  NA     L+  +  V+SDELNH S+I GIRL  A   R++H ++  LE +L         K  +K +  LV  +G +SM+G I  L +I  L  +Y   +++DE H+ G LG  GRG  +   +   +V I   T  K+   +SGGY +G   L+  +R++S   ++  ++   +      A+ ++            I+ +A  T  FR+ +   G  V G  + P+ PV++
Sbjct:   39 GTWKSERVITSRQGPSIRVDGISGGILNFCANNYLGLSSHPAVIQAGLQ-TLEEFGAGLSSTRFICGTQSIHKNLEAKIAHFHQREDAILYPSCFDANAGLFEALLTPEDAVLSDELNHASIIDGIRLCKAHKYRYRHLDMADLEAKL---------KEAQKHRLRLVATDGAFSMDGDIAPLQDICRLAAQYGALVFVDECHATGFLGPTGRGTDELLGVM-DQVTIINSTLGKALGGASGGYTTGPEPLVSLLRQRSRPYLFSNSLPPAVVGCASKALDLL------MESNAIIQSMAAKTRRFRSKMEAAGFTVSG-ADHPICPVML 350
[Close]
BLAST of Serine palmitoyltransferase 2 vs. UniProt/SwissProt
Match: sp|P97363|SPTC2_MOUSE (Serine palmitoyltransferase 2 OS=Mus musculus OX=10090 GN=Sptlc2 PE=1 SV=2)

HSP 1 Score: 537.339 bits (1383), Expect = 0.000e+0
Identity = 261/499 (52.30%), Postives = 348/499 (69.74%), Query Frame = 1 
Query:   40 GHIKSIKQETKCKESEFFEQFEKASLFNSLITYLYFFILKCMGKLRDFMRNYGLEKNRLAVDSTKNKGFAPLYLDFEAFYTRNVYRRVCDCVNKPICSAPGGSLKAMNRVSDDHNWTFRILDST-SDIYNFGSYNYLGFAQNDGLCTDYVEKSINEFGLSVGSPRQEVGNTLYHLELEESLAEFLGQEAAIVFPMGFATNALNIPILVDKDCCVISDELNHVSLILGIRLSGADTRRFKHNNVESLERELIKAITEGHSKTKRKFKKILVVVEGVYSMEGSIVRLPEILELKKKYKFYIYLDEAHSIGALGKGGRGVVDYFNLNPHEVDIQMGTFTKSFASSGGYISGSRNLIHYVREKSHSTIYGGTMSGPICQQILSAMAIIGGKMGGSLGAERIRQLAWNTTYFRAALHRMGLIVFGNKNSPVIPVIVYTIPKVVAFHRECMRRGIGTVIVGYPACNLKLARIRFCISAAHTKRSLDYTLSIVDEIATHLRFKYSR 1533
            G I  + +     +  F E FE+  +  +++TY+ + +L   G LRDF+R++ +EK   A +  + K F  LY DFE FYTRN+Y R+ D  N+PICS PG  +  M R S D+NW+F+   +    + N GSYNYLGFA+N G C +   + + E+G  V S RQE+GN   H ELE+ +A FLG EAA+ + MGFATN++NIP LV K C ++SDELNH SL+LG RLSGA  R FKHNN++SLE+ L  AI  G  +T+R +KKIL++VEG+YSMEGSIVRLPE++ LKKKYK Y+YLDEAHSIGALG  GRGVVDYF L+P +VD+ MGTFTKSF +SGGYI G + LI Y+R  SHS +Y  +MS P+ +QI+++M  I G+ G SLG E I+QLA NT YFR  L  MG I++GN++SPV+P+++Y   K+ AF RE ++R IG V+VG+PA  +  +R RFC+SAAHTK  LD  L  +DE+   L+ KYSR
Sbjct:   41 GQIHHVTENGGLYKRPFNEAFEETPMLVAVLTYVGYGVLTLFGYLRDFLRHWRIEKCHHATEREEQKDFVSLYQDFENFYTRNLYMRIRDNWNRPICSVPGAKVDIMERKSHDYNWSFKYTGNIIKGVINMGSYNYLGFARNTGSCQEAAAEVLKEYGAGVCSTRQEIGNLDKHEELEKLVARFLGVEAAMTYGMGFATNSMNIPALVGKGCLILSDELNHASLVLGARLSGATIRIFKHNNMQSLEKLLKDAIVYGQPRTRRPWKKILILVEGIYSMEGSIVRLPEVIALKKKYKAYLYLDEAHSIGALGPSGRGVVDYFGLDPEDVDVMMGTFTKSFGASGGYIGGKKELIDYLRTHSHSAVYATSMSPPVMEQIITSMKCIMGQDGTSLGKECIQQLAENTRYFRRRLKEMGFIIYGNEDSPVVPLMLYMPAKIGAFGREMLKRNIGVVVVGFPATPIIESRARFCLSAAHTKEILDTALKEIDEVGDLLQLKYSR 539
[Close]
BLAST of Serine palmitoyltransferase 2 vs. UniProt/SwissProt
Match: sp|Q3B7D2|SPTC2_RAT (Serine palmitoyltransferase 2 OS=Rattus norvegicus OX=10116 GN=Sptlc2 PE=1 SV=1)

HSP 1 Score: 536.569 bits (1381), Expect = 0.000e+0
Identity = 263/504 (52.18%), Postives = 350/504 (69.44%), Query Frame = 1 
Query:   40 GHIKSIKQETKCKESEFFEQFEKASLFNSLITYLYFFILKCMGKLRDFMRNYGLEKNRLAVDSTKNKGFAPLYLDFEAFYTRNVYRRVCDCVNKPICSAPGGSLKAMNRVSDDHNWTFRILDST-SDIYNFGSYNYLGFAQNDGLCTDYVEKSINEFGLSVGSPRQEVGNTLYHLELEESLAEFLGQEAAIVFPMGFATNALNIPILVDKDCCVISDELNHVSLILGIRLSGADTRRFKHNNVESLERELIKAITEGHSKTKRKFKKILVVVEGVYSMEGSIVRLPEILELKKKYKFYIYLDEAHSIGALGKGGRGVVDYFNLNPHEVDIQMGTFTKSFASSGGYISGSRNLIHYVREKSHSTIYGGTMSGPICQQILSAMAIIGGKMGGSLGAERIRQLAWNTTYFRAALHRMGLIVFGNKNSPVIPVIVYTIPKVVAFHRECMRRGIGTVIVGYPACNLKLARIRFCISAAHTKRSLDYTLSIVDEIATHLRFKYSR-LPVP 1545
            G I  I +     +  F E FE+  +  +++TY+ + +L   G LRDF+R++ +EK   A +  + K F  LY DFE FYTRN+Y R+ D  N+PICS PG  +  M R S D+NW+F+   +    + N GSYNYLGFA+N G C +   + +  +G  V S RQE+GN   H ELE+ +A FLG EAA+ + MGFATN++NIP LV K C ++SDELNH SL+LG RLSGA  R FKHNN++SLE+ L  AI  G  +T+R +KKIL++VEG+YSMEGSIVRLPE++ LKKKYK Y+YLDEAHSIGALG  GRGVVDYF L+P +VD+ MGTFTKSF +SGGYI G + LI Y+R  SHS +Y  +MS P+ +QI+++M  I G+ G SLG E I+QLA NT YFR  L  MG I++GN++SPV+P+++Y   K+ AF RE ++R IG V+VG+PA  +  +R RFC+SAAHTK  LD  L  +DE+   L+ KYSR  P+P
Sbjct:   41 GQIHHITENGGLYKRPFNEAFEETPMLVAVLTYVGYGVLTLFGYLRDFLRHWRIEKCHHATEREEQKDFVSLYQDFENFYTRNLYMRIRDNWNRPICSVPGAKVDIMERQSHDYNWSFKYTGNIIKGVINMGSYNYLGFARNTGSCQEAAAEVLKTYGAGVCSTRQEIGNLDKHEELEKLVARFLGVEAALTYGMGFATNSMNIPALVGKGCLILSDELNHASLVLGARLSGATIRIFKHNNMQSLEKLLKDAIVYGQPRTRRPWKKILILVEGIYSMEGSIVRLPEVIALKKKYKAYLYLDEAHSIGALGPSGRGVVDYFGLDPEDVDVMMGTFTKSFGASGGYIGGKKELIDYLRTHSHSAVYATSMSPPVMEQIITSMKCIMGQDGTSLGKECIQQLAENTRYFRRRLKEMGFIIYGNEDSPVVPLMLYMPAKIGAFGREMLKRNIGVVVVGFPATPIIESRARFCLSAAHTKEILDTALKEIDEVGDLLQLKYSRHRPLP 544
[Close]
BLAST of Serine palmitoyltransferase 2 vs. UniProt/SwissProt
Match: sp|O15270|SPTC2_HUMAN (Serine palmitoyltransferase 2 OS=Homo sapiens OX=9606 GN=SPTLC2 PE=1 SV=1)

HSP 1 Score: 536.184 bits (1380), Expect = 0.000e+0
Identity = 261/499 (52.30%), Postives = 347/499 (69.54%), Query Frame = 1 
Query:   40 GHIKSIKQETKCKESEFFEQFEKASLFNSLITYLYFFILKCMGKLRDFMRNYGLEKNRLAVDSTKNKGFAPLYLDFEAFYTRNVYRRVCDCVNKPICSAPGGSLKAMNRVSDDHNWTFRILDST-SDIYNFGSYNYLGFAQNDGLCTDYVEKSINEFGLSVGSPRQEVGNTLYHLELEESLAEFLGQEAAIVFPMGFATNALNIPILVDKDCCVISDELNHVSLILGIRLSGADTRRFKHNNVESLERELIKAITEGHSKTKRKFKKILVVVEGVYSMEGSIVRLPEILELKKKYKFYIYLDEAHSIGALGKGGRGVVDYFNLNPHEVDIQMGTFTKSFASSGGYISGSRNLIHYVREKSHSTIYGGTMSGPICQQILSAMAIIGGKMGGSLGAERIRQLAWNTTYFRAALHRMGLIVFGNKNSPVIPVIVYTIPKVVAFHRECMRRGIGTVIVGYPACNLKLARIRFCISAAHTKRSLDYTLSIVDEIATHLRFKYSR 1533
            G I  + Q     +  F E FE+  +  +++TY+ + +L   G LRDF+R + +EK   A +  + K F  LY DFE FYTRN+Y R+ D  N+PICS PG  +  M R S D+NW+F+   +    + N GSYNYLGFA+N G C +   K + E+G  V S RQE+GN   H ELEE +A FLG EAA+ + MGFATN++NIP LV K C ++SDELNH SL+LG RLSGA  R FKHNN++SLE+ L  AI  G  +T+R +KKIL++VEG+YSMEGSIVRLPE++ LKKKYK Y+YLDEAHSIGALG  GRGVV+YF L+P +VD+ MGTFTKSF +SGGYI G + LI Y+R  SHS +Y  ++S P+ +QI+++M  I G+ G SLG E ++QLA NT YFR  L  MG I++GN++SPV+P+++Y   K+ AF RE ++R IG V+VG+PA  +  +R RFC+SAAHTK  LD  L  +DE+   L+ KYSR
Sbjct:   43 GQIHHVTQNGGLYKRPFNEAFEETPMLVAVLTYVGYGVLTLFGYLRDFLRYWRIEKCHHATEREEQKDFVSLYQDFENFYTRNLYMRIRDNWNRPICSVPGARVDIMERQSHDYNWSFKYTGNIIKGVINMGSYNYLGFARNTGSCQEAAAKVLEEYGAGVCSTRQEIGNLDKHEELEELVARFLGVEAAMAYGMGFATNSMNIPALVGKGCLILSDELNHASLVLGARLSGATIRIFKHNNMQSLEKLLKDAIVYGQPRTRRPWKKILILVEGIYSMEGSIVRLPEVIALKKKYKAYLYLDEAHSIGALGPTGRGVVEYFGLDPEDVDVMMGTFTKSFGASGGYIGGKKELIDYLRTHSHSAVYATSLSPPVVEQIITSMKCIMGQDGTSLGKECVQQLAENTRYFRRRLKEMGFIIYGNEDSPVVPLMLYMPAKIGAFGREMLKRNIGVVVVGFPATPIIESRARFCLSAAHTKEILDTALKEIDEVGDLLQLKYSR 541
[Close]
BLAST of Serine palmitoyltransferase 2 vs. UniProt/SwissProt
Match: sp|O54694|SPTC2_CRIGR (Serine palmitoyltransferase 2 OS=Cricetulus griseus OX=10029 GN=SPTLC2 PE=2 SV=1)

HSP 1 Score: 535.028 bits (1377), Expect = 0.000e+0
Identity = 259/499 (51.90%), Postives = 348/499 (69.74%), Query Frame = 1 
Query:   40 GHIKSIKQETKCKESEFFEQFEKASLFNSLITYLYFFILKCMGKLRDFMRNYGLEKNRLAVDSTKNKGFAPLYLDFEAFYTRNVYRRVCDCVNKPICSAPGGSLKAMNRVSDDHNWTFRILDST-SDIYNFGSYNYLGFAQNDGLCTDYVEKSINEFGLSVGSPRQEVGNTLYHLELEESLAEFLGQEAAIVFPMGFATNALNIPILVDKDCCVISDELNHVSLILGIRLSGADTRRFKHNNVESLERELIKAITEGHSKTKRKFKKILVVVEGVYSMEGSIVRLPEILELKKKYKFYIYLDEAHSIGALGKGGRGVVDYFNLNPHEVDIQMGTFTKSFASSGGYISGSRNLIHYVREKSHSTIYGGTMSGPICQQILSAMAIIGGKMGGSLGAERIRQLAWNTTYFRAALHRMGLIVFGNKNSPVIPVIVYTIPKVVAFHRECMRRGIGTVIVGYPACNLKLARIRFCISAAHTKRSLDYTLSIVDEIATHLRFKYSR 1533
            G I  + +     +  F E FE+  +  +++TY+ + +L   G LRDF+R++ +EK   A +  + K F  LY DFE FYTRN+Y R+ D  N+PICS PG  +  M R S D+NW+F+   +    + N GSYNYLGFA+N G C +   + + E+G  V S RQE+GN   H ELE+ +A FLG EAA+ + MGFATN++NIP LV K C ++SDELNH SL+LG RLSGA  R FKHNN++SLE+ L  AI  G  +T+R +KKIL++VEG+YSMEGSIVRLPE++ LKKKYK Y+YLDEAHSIGALG  GRGVVDYF L+P +VD+ MGTFTKSF +SGGYI G + LI Y+R  SHS +Y  +MS P+ +QI+++M  I G+ G SLG E ++QLA NT YFR  L  MG I++GN++SPV+P+++Y   K+ AF RE ++R +G V+VG+PA  +  +R RFC+SAAHTK  LD  L  +DE+   L+ KYSR
Sbjct:   41 GQIHHVTENGGLYKRPFNEVFEETPMLVAVLTYVGYGVLTLFGYLRDFLRHWRIEKCHHATEREEQKDFVSLYQDFENFYTRNLYMRIRDNWNRPICSVPGARVDIMERQSHDYNWSFKYTGNIIKGVINMGSYNYLGFARNTGSCQEAAAEVLKEYGAGVCSTRQEIGNLDKHEELEKLVARFLGVEAAMTYGMGFATNSMNIPALVGKGCLILSDELNHASLVLGARLSGATIRIFKHNNMQSLEKLLKDAIVYGQPRTRRPWKKILILVEGIYSMEGSIVRLPEVIALKKKYKAYLYLDEAHSIGALGPSGRGVVDYFGLDPEDVDVMMGTFTKSFGASGGYIGGKKALIDYLRTHSHSAVYATSMSPPVMEQIITSMKCIMGQDGTSLGKECVQQLAENTKYFRRRLKEMGFIIYGNEDSPVVPLMLYMPAKIGAFGREMLKRNVGVVVVGFPATPIIESRARFCLSAAHTKEILDTALKEIDEVGDLLQLKYSR 539
[Close]
BLAST of Serine palmitoyltransferase 2 vs. UniProt/SwissProt
Match: sp|Q9NUV7|SPTC3_HUMAN (Serine palmitoyltransferase 3 OS=Homo sapiens OX=9606 GN=SPTLC3 PE=1 SV=3)

HSP 1 Score: 526.554 bits (1355), Expect = 0.000e+0
Identity = 259/502 (51.59%), Postives = 342/502 (68.13%), Query Frame = 1 
Query:   37 NGHIKSIKQETKCK--ESEFFEQFEKASLFNSLITYLYFFILKCMGKLRDFMRNYGLEKNRLAVDSTKNKGFAPLYLDFEAFYTRNVYRRVCDCVNKPICSAPGGSLKAMNRVSDDHNWTFRILDST-SDIYNFGSYNYLGFAQNDGLCTDYVEKSINEFGLSVGSPRQEVGNTLYHLELEESLAEFLGQEAAIVFPMGFATNALNIPILVDKDCCVISDELNHVSLILGIRLSGADTRRFKHNNVESLERELIKAITEGHSKTKRKFKKILVVVEGVYSMEGSIVRLPEILELKKKYKFYIYLDEAHSIGALGKGGRGVVDYFNLNPHEVDIQMGTFTKSFASSGGYISGSRNLIHYVREKSHSTIYGGTMSGPICQQILSAMAIIGGKMGGSLGAERIRQLAWNTTYFRAALHRMGLIVFGNKNSPVIPVIVYTIPKVVAFHRECMRRGIGTVIVGYPACNLKLARIRFCISAAHTKRSLDYTLSIVDEIATHLRFKYSR 1533
            NG +K  +Q  K    +    E FE+A L   + TY+ + I    G LRDF+RN+G+EK   AV+  + K F PLY DFE FYTRN+Y R+ D  N+PICSAPG     M RVSDD+NWTFR       D+ N GSYN+LG A         ++  +  +G  V S R E+G    H ELE+ +A+FL  EAA+VF MGFATN++NIP LV K C ++SDELNH SL+LG RLSGA  R FKHNN +SLE+ L  A+  G  +T+R +KKIL++VEGVYSMEGSIV LP+I+ LKKKYK Y+Y+DEAHSIGA+G  GRGV ++F L+PHEVD+ MGTFTKSF +SGGYI+G ++L+ Y+R  SHS +Y  +MS PI +QI+ ++ +I G  G + G +R++QLA NT YFR  L  MG I++GN+N+ V+P+++Y   KV AF R  + + IG V+VG+PA  L  AR RFC+SAAHT+  LD  L  +DE+   L+ KYSR
Sbjct:   32 NGIVKEAQQNGKPHFYDKLIVESFEEAPLHVMVFTYMGYGIGTLFGYLRDFLRNWGIEKCNAAVERKEQKDFVPLYQDFENFYTRNLYMRIRDNWNRPICSAPGPLFDLMERVSDDYNWTFRFTGRVIKDVINMGSYNFLGLAAKYDESMRTIKDVLEVYGTGVASTRHEMGTLDKHKELEDLVAKFLNVEAAMVFGMGFATNSMNIPALVGKGCLILSDELNHTSLVLGARLSGATIRIFKHNNTQSLEKLLRDAVIYGQPRTRRAWKKILILVEGVYSMEGSIVHLPQIIALKKKYKAYLYIDEAHSIGAVGPTGRGVTEFFGLDPHEVDVLMGTFTKSFGASGGYIAGRKDLVDYLRVHSHSAVYASSMSPPIAEQIIRSLKLIMGLDGTTQGLQRVQQLAKNTRYFRQRLQEMGFIIYGNENASVVPLLLYMPGKVAAFARHMLEKKIGVVVVGFPATPLAEARARFCVSAAHTREMLDTVLEALDEMGDLLQLKYSR 533
[Close]
BLAST of Serine palmitoyltransferase 2 vs. TrEMBL
Match: A0A068XW60 (Serine palmitoyltransferase long chain base OS=Echinococcus multilocularis OX=6211 GN=EmuJ_000374100 PE=3 SV=1)

HSP 1 Score: 600.127 bits (1546), Expect = 0.000e+0
Identity = 291/522 (55.75%), Postives = 374/522 (71.65%), Query Frame = 1 
Query:   88 FFEQFEKASLFNSLITYLYFFILKCMGKLRDFMRNYGLEKNRLAVDSTKNKGFAPLYLDFEAFYTRNVYRRVCDCVNKPICSAPGGSLKAMNRVSDDHNWTFRILDSTSDIYNFGSYNYLGFAQNDGLCTDYVEKSINEFGLSVGSPRQEVGNTLYHLELEESLAEFLGQEAAIVFPMGFATNALNIPILVDKDCCVISDELNHVSLILGIRLSGADTRRFKHNNVESLERELIKAITEGHSKTKRKFKKILVVVEGVYSMEGSIVRLPEILELKKKYKFYIYLDEAHSIGALGKGGRGVVDYFNLNPHEVDIQMGTFTKSFASSGGYISGSRNLIHYVREKSHSTIYGGTMSGPICQQILSAMAIIGGKMGGSLGAERIRQLAWNTTYFRAALHRMGLIVFGNKNSPVIPVIVYTIPKVVAFHRECMRRGIGTVIVGYPACNLKLARIRFCISAAHTKRSLDYTLSIVDEIATHLRFKYSRLPVPDWCKNVPQRSLIFNENKCCDKYDSCKISISNGKFTA 1653
            F+E FE+ SL N+++TY+ F IL  +G+L+DF+R +GL  N  A +    + F PLY D+EAFYTRN+YRR  DC N+PICS PG  +  M+RVS D  WTF + ++T+ + NFGSYNYLGFA+  G C +   KSI ++GL V S R EVG    H ELE+ +AEF+GQEAAIVF MGFATNALN+P + DK+ C+ISDELNH SLILG RLSGA  RRFKHN+++ LER L  A+  G  +++R F +I ++VEG+YSMEGSI  +PEI+ LKKKYK Y+YLDEAHSIGALG  GRGVVDYF L+P ++DI MGTFTKSF S+GGY++GS  LI YVR +S+S+IYGGTM  P+CQQI+++M II G+     G  R++QLAWNT YFRA LH+MGLIVFGN++SPVIP+I+Y   K+VAF R C+ RG+G VIVG+PA  L  +R RFCISA HTK  LD  L ++ E+   L  ++SRLP P W K       I        K  +  +S+ NG  T+
Sbjct:   19 FYESFEEISLKNAVLTYMSFLILNLLGRLQDFLRKHGLLNNPAAKEKEVTRSFVPLYSDYEAFYTRNIYRRARDCWNRPICSTPGPEMVLMDRVSSDSCWTFEMTNTTTKVLNFGSYNYLGFAEPTGPCIEADVKSIEKYGLGVASSRLEVGTLAVHEELEKLVAEFVGQEAAIVFGMGFATNALNMPCIFDKNSCIISDELNHTSLILGCRLSGATIRRFKHNDMQDLERLLADAVVYGRPRSRRPFSRIFIIVEGIYSMEGSIAHMPEIIALKKKYKAYLYLDEAHSIGALGPRGRGVVDYFGLDPADIDIAMGTFTKSFGSAGGYLAGSARLIDYVRTQSYSSIYGGTMPAPVCQQIVTSMRIIMGRECPGEGERRLKQLAWNTRYFRAHLHQMGLIVFGNRDSPVIPIILYMPGKLVAFSRMCLERGLGVVIVGFPATALLASRSRFCISAGHTKEMLDKALRVIAEVTDELHLRWSRLPPPYWTK-----VYIHGNRNGVQKNKASVLSLPNGHQTS 535
[Close]
BLAST of Serine palmitoyltransferase 2 vs. TrEMBL
Match: A0A4Z2DW01 (Serine palmitoyltransferase 2 OS=Schistosoma japonicum OX=6182 GN=EWB00_004105 PE=3 SV=1)

HSP 1 Score: 597.43 bits (1539), Expect = 0.000e+0
Identity = 275/492 (55.89%), Postives = 365/492 (74.19%), Query Frame = 1 
Query:   88 FFEQFEKASLFNSLITYLYFFILKCMGKLRDFMRNYGLEKNRLAVDSTKNKGFAPLYLDFEAFYTRNVYRRVCDCVNKPICSAPGGSLKAMNRVSDDHNWTFRILDSTSDIYNFGSYNYLGFAQNDGLCTDYVEKSINEFGLSVGSPRQEVGNTLYHLELEESLAEFLGQEAAIVFPMGFATNALNIPILVDKDCCVISDELNHVSLILGIRLSGADTRRFKHNNVESLERELIKAITEGHSKTKRKFKKILVVVEGVYSMEGSIVRLPEILELKKKYKFYIYLDEAHSIGALGKGGRGVVDYFNLNPHEVDIQMGTFTKSFASSGGYISGSRNLIHYVREKSHSTIYGGTMSGPICQQILSAMAIIGGKMGGSLGAERIRQLAWNTTYFRAALHRMGLIVFGNKNSPVIPVIVYTIPKVVAFHRECMRRGIGTVIVGYPACNLKLARIRFCISAAHTKRSLDYTLSIVDEIATHLRFKYSRLPVPDWCKNV 1563
            F+E FE+A LF +++TY+ F IL  +G+L+DF+R + + KN   ++ ++ K F PLY  +EAFYTRN+YRRV DC N+PICSAPG  +  M+R S D  WT  +  +TS + N GSYNYLGF    G CTD  EK   +FG+ V S RQE G+ + H ELE+ +AEF+GQEAAIVF MGF+TN+LN+P LVDK+CCV+SDELNH SL+LG RL+GA  RRFKHN+++ LER L   +  G  +T R +KKILVVVEG+YSMEGSI+ LPE++ LKKKYK Y+YLDEAHSIGALG+ GRGV DYF ++P ++D+ MGTFTKSF S GGY++G++ LI Y+R  S++ +YGG+MS PI QQI+SAM I+ GK     G  R++ LA N  YFRA LH M LIV+GN++SPV+P+IVY   K+ AF R C+  G+GTV+VG+PA  L L+R+RFCIS++HT+  LD  LSI+D++A  L  +YS+  +P+W K V
Sbjct:   13 FYESFEEAPLFTAVLTYMSFLILNILGRLQDFLRFFHVLKNHAVMEPSRTKSFVPLYSSYEAFYTRNLYRRVQDCWNRPICSAPGSEIVVMDRKSPDCGWTLNLTGTTSKVLNLGSYNYLGFGDPIGPCTDATEKMTRKFGVGVASSRQEAGSLVLHKELEDLVAEFVGQEAAIVFSMGFSTNSLNLPCLVDKECCVVSDELNHTSLVLGCRLTGATVRRFKHNDMDDLERVLQDCVVFGRPRTHRPYKKILVVVEGIYSMEGSILHLPEVIALKKKYKAYLYLDEAHSIGALGQMGRGVADYFGVDPRDIDVSMGTFTKSFGSCGGYLAGNQKLIDYLRSVSYNVVYGGSMSAPIAQQIISAMRIVMGKDVPCEGERRLKCLAENIRYFRARLHEMRLIVYGNRDSPVVPIIVYMPAKLAAFSRRCLELGLGTVVVGFPATTLLLSRVRFCISSSHTRELLDRALSIIDQVAEELGLRYSKQAIPEWAKEV 504
[Close]
BLAST of Serine palmitoyltransferase 2 vs. TrEMBL
Match: A0A068X116 (Serine palmitoyltransferase long chain base OS=Echinococcus granulosus OX=6210 GN=EgrG_000374100 PE=3 SV=1)

HSP 1 Score: 596.275 bits (1536), Expect = 0.000e+0
Identity = 282/490 (57.55%), Postives = 364/490 (74.29%), Query Frame = 1 
Query:   88 FFEQFEKASLFNSLITYLYFFILKCMGKLRDFMRNYGLEKNRLAVDSTKNKGFAPLYLDFEAFYTRNVYRRVCDCVNKPICSAPGGSLKAMNRVSDDHNWTFRILDSTSDIYNFGSYNYLGFAQNDGLCTDYVEKSINEFGLSVGSPRQEVGNTLYHLELEESLAEFLGQEAAIVFPMGFATNALNIPILVDKDCCVISDELNHVSLILGIRLSGADTRRFKHNNVESLERELIKAITEGHSKTKRKFKKILVVVEGVYSMEGSIVRLPEILELKKKYKFYIYLDEAHSIGALGKGGRGVVDYFNLNPHEVDIQMGTFTKSFASSGGYISGSRNLIHYVREKSHSTIYGGTMSGPICQQILSAMAIIGGKMGGSLGAERIRQLAWNTTYFRAALHRMGLIVFGNKNSPVIPVIVYTIPKVVAFHRECMRRGIGTVIVGYPACNLKLARIRFCISAAHTKRSLDYTLSIVDEIATHLRFKYSRLPVPDWCK 1557
            F+E FE+ SL N+++TY+ F IL  +G+L+DF+R +GL  +  A +    + F PLY D+EAFYTRN+YRR  DC N+PICS PG  +  M+RVS D  WTF + ++T+ + NFGSYNYLGFA+  G C +   KSI ++GL V S R EVG    H ELE+ +AEF+GQEAAIVF MGFATNALN+P + DK+ C+ISDELNH SLILG RLSGA  RRFKHN+++ LER L  A+  G  +++R F +I ++VEG+YSMEGSI  +PEI+ LKKKYK Y+Y+DEAHSIGALG  GRGVVDYF L+P ++DI MGTFTKSF S+GGY++GS  LI YVR +S+S+IYGGTM  P+CQQI+++M II G+     G  R++QLAWNT YFRA LH+MGLI+FGN++SPVIP+I+Y   K+VAF R C+ RG+G VIVG+PA  L  +R RFCISA HTK  LD  L ++ E+   L  ++SRLP P W K
Sbjct:   19 FYESFEEISLKNAVLTYMSFLILNLLGRLQDFLRKHGLLNDPAAKEKEVTRSFVPLYSDYEAFYTRNIYRRARDCWNRPICSTPGPEMVLMDRVSSDSCWTFEMTNTTTKVLNFGSYNYLGFAEPSGPCIEADVKSIEKYGLGVASSRLEVGTLAVHEELEKLVAEFVGQEAAIVFGMGFATNALNMPCIFDKNSCIISDELNHTSLILGCRLSGATIRRFKHNDMQDLERLLADAVVYGRPRSRRPFSRIFIIVEGIYSMEGSIAHMPEIIALKKKYKAYLYVDEAHSIGALGPRGRGVVDYFGLDPADIDIAMGTFTKSFGSAGGYLAGSARLIDYVRTQSYSSIYGGTMPAPVCQQIVTSMRIIMGRECPGEGERRLKQLAWNTRYFRAHLHQMGLIIFGNRDSPVIPIILYMPGKLVAFSRMCLERGLGVVIVGFPATGLLASRSRFCISAGHTKEMLDKALRVIAEVTDELHLRWSRLPPPYWTK 508
[Close]
BLAST of Serine palmitoyltransferase 2 vs. TrEMBL
Match: A0A564Y756 (Aminotran_1_2 domain-containing protein OS=Hymenolepis diminuta OX=6216 GN=WMSIL1_LOCUS4081 PE=3 SV=1)

HSP 1 Score: 595.89 bits (1535), Expect = 0.000e+0
Identity = 285/503 (56.66%), Postives = 368/503 (73.16%), Query Frame = 1 
Query:   43 HIKSIKQETKCKESEFFEQFEKASLFNSLITYLYFFILKCMGKLRDFMRNYGLEKNRLAVDSTKNKGFAPLYLDFEAFYTRNVYRRVCDCVNKPICSAPGGSLKAMNRVSDDHNWTFRILDSTSDIYNFGSYNYLGFAQNDGLCTDYVEKSINEFGLSVGSPRQEVGNTLYHLELEESLAEFLGQEAAIVFPMGFATNALNIPILVDKDCCVISDELNHVSLILGIRLSGADTRRFKHNNVESLERELIKAITEGHSKTKRKFKKILVVVEGVYSMEGSIVRLPEILELKKKYKFYIYLDEAHSIGALGKGGRGVVDYFNLNPHEVDIQMGTFTKSFASSGGYISGSRNLIHYVREKSHSTIYGGTMSGPICQQILSAMAIIGGKMGGSLGAERIRQLAWNTTYFRAALHRMGLIVFGNKNSPVIPVIVYTIPKVVAFHRECMRRGIGTVIVGYPACNLKLARIRFCISAAHTKRSLDYTLSIVDEIATHLRFKYSRLPVPDW 1551
            HIK+           F+E FE+ SL N+++TY+ F IL  +G+L+DF+R +G+  N    +S   K F PLY D+EAFYTRNVYRR  DC N+PICS PG  +  M+RVS D  WTF++ ++TS + NFGSYNYLGFA+  G C D   KSI ++GL + SPR E G    HLELE  +AEF+GQEAAIVF MGFATNALN+P + DK+ C+ISDELNH SLILG RLSGA  RRFKHN++  LE+ L +A+  G  +++R F +I ++VEG+YSMEGSI  +PEI+ LKKKYK Y+YLDEAHSIGALG  GRG+VDYF ++P ++DI MGTFTKSF SSGGY++GS+  I YVR +S+S+IYGGTM  P+CQQI+++M II G+     G  R++QLAWNT YFRA LH+MGLIVFGN++SPVIP+I+Y   K++AF R C+ RG+G V+VG+PA  L  +R RFCISA HTK  LD  L+++ E+A  L    S+LP P W
Sbjct:    4 HIKTTLYAKPRTGEPFYECFEEISLKNAVLTYMSFLILNLLGRLQDFLRKHGILDNPAYKESELTKSFVPLYSDYEAFYTRNVYRRARDCWNRPICSPPGPEMVLMDRVSYDSCWTFQMTNTTSKVLNFGSYNYLGFAEPSGPCIDSDIKSIEKYGLGIASPRLEAGTLDIHLELENLVAEFVGQEAAIVFGMGFATNALNMPRVFDKNSCIISDELNHTSLILGCRLSGATVRRFKHNDMHDLEKCLKEAVVYGRPRSRRPFSRIFIIVEGIYSMEGSIAHMPEIIALKKKYKAYVYLDEAHSIGALGPSGRGIVDYFGIDPKDIDIAMGTFTKSFGSSGGYLAGSKRFIDYVRTESYSSIYGGTMPAPVCQQIITSMKIIMGRECPGEGERRLKQLAWNTRYFRAHLHQMGLIVFGNRDSPVIPLILYMPGKLIAFSRLCLERGLGVVVVGFPATALLASRCRFCISAGHTKEMLDKALAVIKEVADELHLNCSKLPPPYW 506
[Close]
BLAST of Serine palmitoyltransferase 2 vs. TrEMBL
Match: A0A0X3PSW2 (Serine palmitoyltransferase 2 (Fragment) OS=Schistocephalus solidus OX=70667 GN=SPTC2 PE=3 SV=1)

HSP 1 Score: 594.349 bits (1531), Expect = 0.000e+0
Identity = 283/502 (56.37%), Postives = 367/502 (73.11%), Query Frame = 1 
Query:   52 SIKQETKCKES-EFFEQFEKASLFNSLITYLYFFILKCMGKLRDFMRNYGLEKNRLAVDSTKNKGFAPLYLDFEAFYTRNVYRRVCDCVNKPICSAPGGSLKAMNRVSDDHNWTFRILDSTSDIYNFGSYNYLGFAQNDGLCTDYVEKSINEFGLSVGSPRQEVGNTLYHLELEESLAEFLGQEAAIVFPMGFATNALNIPILVDKDCCVISDELNHVSLILGIRLSGADTRRFKHNNVESLERELIKAITEGHSKTKRKFKKILVVVEGVYSMEGSIVRLPEILELKKKYKFYIYLDEAHSIGALGKGGRGVVDYFNLNPHEVDIQMGTFTKSFASSGGYISGSRNLIHYVREKSHSTIYGGTMSGPICQQILSAMAIIGGKMGGSLGAERIRQLAWNTTYFRAALHRMGLIVFGNKNSPVIPVIVYTIPKVVAFHRECMRRGIGTVIVGYPACNLKLARIRFCISAAHTKRSLDYTLSIVDEIATHLRFKYSRLPVPDWC 1554
            +++   K + S +FFE FE+ SL N+++TYL F +L  +G+ +DF+R  G+  N  A +S   K F PLY DFEAFYTRN+YRR  DC N+PICSAPG  +  ++RVS +  WTF    + + + NFGSYNYLGFA+++GLCT+   ++IN +GL V SPR E G    H+ELE+ +AEF+GQEAAIVF MGFATNALN+P + DK+ CVISDELNH SLILG RLSGA  RRFKHN+++ LER L  A+  G  ++ R F KI +V+EG+YSMEGSI RLP+IL LK+KYK Y+YLDEAHSIGALG  GRGVVDYF L+P EVDI MGTFTKSF S+GGY++GSR  I YVR  S ST YGGTM  P+CQQ++++M II G+     G  R++QLA NT YFRA LH++G++V+GN++SPV+P+I+     +VAF R C+ RG+G VIVG+PA  L  +R RFCISA HT+  LD  L+I++EI   L  + SRL +P W 
Sbjct:   26 TVRVSAKARRSNDFFESFEQISLTNAILTYLSFLLLNILGRFQDFLRKIGVLSNPTAKESPLTKDFVPLYSDFEAFYTRNMYRRARDCWNRPICSAPGPVMDLVDRVSHNSCWTFEFTGTKTSVMNFGSYNYLGFAESNGLCTESDIEAINRYGLGVASPRLESGTLKIHMELEKLVAEFVGQEAAIVFGMGFATNALNMPKIFDKNSCVISDELNHTSLILGCRLSGATIRRFKHNDMQDLERILSDAVVYGRPRSHRPFTKIFIVIEGIYSMEGSIARLPDILALKRKYKAYVYLDEAHSIGALGPHGRGVVDYFGLDPSEVDIYMGTFTKSFGSAGGYLAGSRRFIDYVRVHSLSTNYGGTMPAPVCQQVIASMRIIMGRDNEGEGGRRLKQLAENTRYFRARLHQIGVVVYGNRDSPVVPIIICLPGTLVAFSRLCLERGLGVVIVGFPATALLASRSRFCISAGHTREMLDKALAIIEEIVEELGIRNSRLTLPKWA 527
[Close]
BLAST of Serine palmitoyltransferase 2 vs. Ensembl Cavefish
Match: sptlc2a (serine palmitoyltransferase, long chain base subunit 2a [Source:ZFIN;Acc:ZDB-GENE-050522-23])

HSP 1 Score: 533.872 bits (1374), Expect = 0.000e+0
Identity = 256/491 (52.14%), Postives = 346/491 (70.47%), Query Frame = 1 
Query:   88 FFEQFEKASLFNSLITYLYFFILKCMGKLRDFMRNYGLEKNRLAVDSTKNKGFAPLYLDFEAFYTRNVYRRVCDCVNKPICSAPGGSLKAMNRVSDDHNWTFRILDST-SDIYNFGSYNYLGFAQNDGLCTDYVEKSINEFGLSVGSPRQEVGNTLYHLELEESLAEFLGQEAAIVFPMGFATNALNIPILVDKDCCVISDELNHVSLILGIRLSGADTRRFKHNNVESLERELIKAITEGHSKTKRKFKKILVVVEGVYSMEGSIVRLPEILELKKKYKFYIYLDEAHSIGALGKGGRGVVDYFNLNPHEVDIQMGTFTKSFASSGGYISGSRNLIHYVREKSHSTIYGGTMSGPICQQILSAMAIIGGKMGGSLGAERIRQLAWNTTYFRAALHRMGLIVFGNKNSPVIPVIVYTIPKVVAFHRECMRRGIGTVIVGYPACNLKLARIRFCISAAHTKRSLDYTLSIVDEIATHLRFKYSR---LPVPD 1548
            F+E FE+  +  +++TY+ + IL   G LRDFMR + +EK  +A +  + K F PLY DFE FYTRN+Y R+ D  N+PICS PG  +  + RVS D+NWTF        D+ N GSYNYLGFA+N G C +   +   ++G+ V S RQE+GN   H E+E+ +A FLG E+A+ F MGFATN++NIP L  K C ++SDELNH SL+LG RLSG+  R FKHNN++SLE+ L  AI  G  +T R +KKIL++VEG+YSMEGSI+RLPE++ LKKKYK Y+YLDEAHSIGALG  GRGVV+YF L+P +VDI MGTFTKSF ++GGYI G + LI Y+R  SHS +Y  +MS P+ +QI+++M  I G+ G ++G ER++QLA NT YFR  L  +G I++GN +SPV+P+++Y   K+ AF RE ++R IG V+VG+PA  +  +R RFC+SA+HTK  LD  L+ + E+   L+ KYSR   LP  D
Sbjct:  130 FYESFEETPMLVAVLTYMGYGILTIFGYLRDFMRQWKIEKCHIAREREEQKDFVPLYQDFENFYTRNLYMRIRDNWNRPICSVPGDKMDLVERVSYDYNWTFGYTGRVVKDVINMGSYNYLGFAENTGSCAEAAAEVTVKYGVGVSSTRQEMGNLDRHEEMEKLVARFLGVESAMAFGMGFATNSMNIPALTGKGCLILSDELNHASLVLGARLSGSTIRVFKHNNMQSLEKLLRDAIVHGQPRTHRPWKKILILVEGIYSMEGSIIRLPEVIALKKKYKAYLYLDEAHSIGALGPSGRGVVEYFGLDPTDVDIMMGTFTKSFGAAGGYIGGKKELIDYLRSHSHSAVYATSMSPPVVEQIITSMKCIMGEDGTTIGRERVQQLAENTVYFRRRLREIGFIIYGNNDSPVVPLMLYLPAKIGAFGREMLKRNIGVVVVGFPATPIIESRARFCVSASHTKEMLDQALNAISEVGDLLQVKYSRHRILPALD 620
[Close]
BLAST of Serine palmitoyltransferase 2 vs. Ensembl Cavefish
Match: sptlc2a (serine palmitoyltransferase, long chain base subunit 2a [Source:ZFIN;Acc:ZDB-GENE-050522-23])

HSP 1 Score: 533.872 bits (1374), Expect = 0.000e+0
Identity = 256/491 (52.14%), Postives = 346/491 (70.47%), Query Frame = 1 
Query:   88 FFEQFEKASLFNSLITYLYFFILKCMGKLRDFMRNYGLEKNRLAVDSTKNKGFAPLYLDFEAFYTRNVYRRVCDCVNKPICSAPGGSLKAMNRVSDDHNWTFRILDST-SDIYNFGSYNYLGFAQNDGLCTDYVEKSINEFGLSVGSPRQEVGNTLYHLELEESLAEFLGQEAAIVFPMGFATNALNIPILVDKDCCVISDELNHVSLILGIRLSGADTRRFKHNNVESLERELIKAITEGHSKTKRKFKKILVVVEGVYSMEGSIVRLPEILELKKKYKFYIYLDEAHSIGALGKGGRGVVDYFNLNPHEVDIQMGTFTKSFASSGGYISGSRNLIHYVREKSHSTIYGGTMSGPICQQILSAMAIIGGKMGGSLGAERIRQLAWNTTYFRAALHRMGLIVFGNKNSPVIPVIVYTIPKVVAFHRECMRRGIGTVIVGYPACNLKLARIRFCISAAHTKRSLDYTLSIVDEIATHLRFKYSR---LPVPD 1548
            F+E FE+  +  +++TY+ + IL   G LRDFMR + +EK  +A +  + K F PLY DFE FYTRN+Y R+ D  N+PICS PG  +  + RVS D+NWTF        D+ N GSYNYLGFA+N G C +   +   ++G+ V S RQE+GN   H E+E+ +A FLG E+A+ F MGFATN++NIP L  K C ++SDELNH SL+LG RLSG+  R FKHNN++SLE+ L  AI  G  +T R +KKIL++VEG+YSMEGSI+RLPE++ LKKKYK Y+YLDEAHSIGALG  GRGVV+YF L+P +VDI MGTFTKSF ++GGYI G + LI Y+R  SHS +Y  +MS P+ +QI+++M  I G+ G ++G ER++QLA NT YFR  L  +G I++GN +SPV+P+++Y   K+ AF RE ++R IG V+VG+PA  +  +R RFC+SA+HTK  LD  L+ + E+   L+ KYSR   LP  D
Sbjct:  151 FYESFEETPMLVAVLTYMGYGILTIFGYLRDFMRQWKIEKCHIAREREEQKDFVPLYQDFENFYTRNLYMRIRDNWNRPICSVPGDKMDLVERVSYDYNWTFGYTGRVVKDVINMGSYNYLGFAENTGSCAEAAAEVTVKYGVGVSSTRQEMGNLDRHEEMEKLVARFLGVESAMAFGMGFATNSMNIPALTGKGCLILSDELNHASLVLGARLSGSTIRVFKHNNMQSLEKLLRDAIVHGQPRTHRPWKKILILVEGIYSMEGSIIRLPEVIALKKKYKAYLYLDEAHSIGALGPSGRGVVEYFGLDPTDVDIMMGTFTKSFGAAGGYIGGKKELIDYLRSHSHSAVYATSMSPPVVEQIITSMKCIMGEDGTTIGRERVQQLAENTVYFRRRLREIGFIIYGNNDSPVVPLMLYLPAKIGAFGREMLKRNIGVVVVGFPATPIIESRARFCVSASHTKEMLDQALNAISEVGDLLQVKYSRHRILPALD 641
[Close]
BLAST of Serine palmitoyltransferase 2 vs. Ensembl Cavefish
Match: sptlc2a (serine palmitoyltransferase, long chain base subunit 2a [Source:ZFIN;Acc:ZDB-GENE-050522-23])

HSP 1 Score: 533.872 bits (1374), Expect = 0.000e+0
Identity = 256/491 (52.14%), Postives = 346/491 (70.47%), Query Frame = 1 
Query:   88 FFEQFEKASLFNSLITYLYFFILKCMGKLRDFMRNYGLEKNRLAVDSTKNKGFAPLYLDFEAFYTRNVYRRVCDCVNKPICSAPGGSLKAMNRVSDDHNWTFRILDST-SDIYNFGSYNYLGFAQNDGLCTDYVEKSINEFGLSVGSPRQEVGNTLYHLELEESLAEFLGQEAAIVFPMGFATNALNIPILVDKDCCVISDELNHVSLILGIRLSGADTRRFKHNNVESLERELIKAITEGHSKTKRKFKKILVVVEGVYSMEGSIVRLPEILELKKKYKFYIYLDEAHSIGALGKGGRGVVDYFNLNPHEVDIQMGTFTKSFASSGGYISGSRNLIHYVREKSHSTIYGGTMSGPICQQILSAMAIIGGKMGGSLGAERIRQLAWNTTYFRAALHRMGLIVFGNKNSPVIPVIVYTIPKVVAFHRECMRRGIGTVIVGYPACNLKLARIRFCISAAHTKRSLDYTLSIVDEIATHLRFKYSR---LPVPD 1548
            F+E FE+  +  +++TY+ + IL   G LRDFMR + +EK  +A +  + K F PLY DFE FYTRN+Y R+ D  N+PICS PG  +  + RVS D+NWTF        D+ N GSYNYLGFA+N G C +   +   ++G+ V S RQE+GN   H E+E+ +A FLG E+A+ F MGFATN++NIP L  K C ++SDELNH SL+LG RLSG+  R FKHNN++SLE+ L  AI  G  +T R +KKIL++VEG+YSMEGSI+RLPE++ LKKKYK Y+YLDEAHSIGALG  GRGVV+YF L+P +VDI MGTFTKSF ++GGYI G + LI Y+R  SHS +Y  +MS P+ +QI+++M  I G+ G ++G ER++QLA NT YFR  L  +G I++GN +SPV+P+++Y   K+ AF RE ++R IG V+VG+PA  +  +R RFC+SA+HTK  LD  L+ + E+   L+ KYSR   LP  D
Sbjct:  151 FYESFEETPMLVAVLTYMGYGILTIFGYLRDFMRQWKIEKCHIAREREEQKDFVPLYQDFENFYTRNLYMRIRDNWNRPICSVPGDKMDLVERVSYDYNWTFGYTGRVVKDVINMGSYNYLGFAENTGSCAEAAAEVTVKYGVGVSSTRQEMGNLDRHEEMEKLVARFLGVESAMAFGMGFATNSMNIPALTGKGCLILSDELNHASLVLGARLSGSTIRVFKHNNMQSLEKLLRDAIVHGQPRTHRPWKKILILVEGIYSMEGSIIRLPEVIALKKKYKAYLYLDEAHSIGALGPSGRGVVEYFGLDPTDVDIMMGTFTKSFGAAGGYIGGKKELIDYLRSHSHSAVYATSMSPPVVEQIITSMKCIMGEDGTTIGRERVQQLAENTVYFRRRLREIGFIIYGNNDSPVVPLMLYLPAKIGAFGREMLKRNIGVVVVGFPATPIIESRARFCVSASHTKEMLDQALNAISEVGDLLQVKYSRHRILPALD 641
[Close]
BLAST of Serine palmitoyltransferase 2 vs. Ensembl Cavefish
Match: gcat (glycine C-acetyltransferase [Source:NCBI gene;Acc:103043864])

HSP 1 Score: 149.443 bits (376), Expect = 5.628e-39
Identity = 109/383 (28.46%), Postives = 184/383 (48.04%), Query Frame = 1 
Query:  340 GGSLKAMNRVSDDHNWTFRILDSTSDIYNFGSYNYLGFAQNDGLCTDYVEKSINEFGLSVGSPRQEVGNTLYHLELEESLAEFLGQEAAIVFPMGFATNALNIPILVDKDCCVISDELNHVSLILGIRLSGADTRRFKHNNVESLERELIKAITEGHSKTKRKFKKILVVVEGVYSMEGSIVRLPEILELKKKYKFYIYLDEAHSIGALGKGGRGVVDYFNLNPHEVDIQMGTFTKSFASSGGYISGSRNLIHYVREKSHSTIYGGTMSGPICQQILSAMAIIGGKMGGSLGAERIRQ-LAWNTTYFRAALHRMGLIVFGNKNSPVIPVIVYTIPKVVAFHRECMRRGIGTVIVGYPACNLKLARIRFCISAAHTKRSLDYTL 1485
             G+ K    ++        +  S++DI NF + NYLG + +  +    +E ++ ++G  + S R   G    H +LE+ LA+F  +E  I++   F  NA    +L+  +  V+SDELNH S+I GIRL  A   R+KH ++  LE +L     E  S   R     LVV +GV+SM+G +  L  I +L ++Y   +++DE H+ G LG  GRG  +   +      +          ++GGY  G + LI  +R++S   ++  ++  P+      A+ ++       L +  I Q +A  T  FR  + + G  + G  + P+ PV++           + ++ G+  +   YP      ARIR  ISAAHT   +D T+
Sbjct:   52 AGTWKGERVITSKQGAHISVDGSSADILNFCANNYLGLSSHPEVIQAGIE-ALQKYGAGLSSVRFICGTQDLHKKLEQKLAQFHEREDCILYASCFDANAGLFEVLLGPEDAVLSDELNHASIIDGIRLCRAKRLRYKHMDLNDLEDKL----KESQSSRLR-----LVVTDGVFSMDGDVAPLVGICDLAEQYGALVFIDECHATGFLGIRGRGTDELLGVMDRVHIVNSTLGKALGGAAGGYTVGPKPLIDLLRQRSRPYLFSNSLPPPVVGSATRAVELL-------LASNEIAQSMAAKTMRFRNGMTQAGFTIAGAAH-PICPVMLGDARLASLMADDMLKLGVYVIGFSYPVVPKGKARIRVQISAAHTDSDIDRTV 416
[Close]
BLAST of Serine palmitoyltransferase 2 vs. Ensembl Cavefish
Match: sptlc1 (serine palmitoyltransferase, long chain base subunit 1 [Source:ZFIN;Acc:ZDB-GENE-050522-61])

HSP 1 Score: 144.436 bits (363), Expect = 7.971e-37
Identity = 86/268 (32.09%), Postives = 144/268 (53.73%), Query Frame = 1 
Query:  388 TFRILDSTSDIYNFGSYNYLGFAQNDGLCTDYVEKSINEFGLSVGSPRQEVGNTLYHLELEESLAEFLGQEAAIVFPMGFATNALNIPILVDKDCCVISDELNHVSLILGIRLSGADTRRFKHNNVESLERELIKAITEGHSKTKR-KFKKILVVVEGVYSMEGSIVRLPEILELKKKYKFYIYLDEAHSIGALGKGGRGVVDYFNLNPHEVDIQMGTFTKSFASSGGYISGSRNLIHYVREKSHSTIYGGTMSGPICQQILSAMAII 1188
            + +I+ +  +  NFGS+N+LG   N+ +    +  S+ ++G+    PR   G    HLELEE LA+F+  E AI++  GFAT A  IP    +   V  DE +  S+  G++ S +  + FKHN++E LER L +   E     ++ +  +  +VVEG+Y     I  LPE+++LK KYK  I+L+E+ S G LG+ GRGV ++F +N  ++D+       + AS GG+  G   +I + R       +  ++   +    + A+ I+
Sbjct:  101 SHKIIVNGKECINFGSFNFLGLLDNERVKQKAL-ASLRKYGVGTCGPRGFYGTFDVHLELEERLAKFMRTEEAIIYSYGFATIASAIPAYSKRGDIVFVDEASCFSIQKGLQASRSFIKYFKHNDMEDLERLLKEQELEDQKNPRKARVTRRFIVVEGLYMNTADICPLPELVKLKYKYKVRIFLEESMSFGVLGEHGRGVTEHFGVNIDDIDLISANMENAVASIGGFCCGRSFVIDHQRLSGQGYCFSASLPPMLASAAIEALNIM 367
[Close]
BLAST of Serine palmitoyltransferase 2 vs. Ensembl Sea Lamprey
Match: sptlc2a (serine palmitoyltransferase, long chain base subunit 2a [Source:ZFIN;Acc:ZDB-GENE-050522-23])

HSP 1 Score: 551.206 bits (1419), Expect = 0.000e+0
Identity = 264/482 (54.77%), Postives = 344/482 (71.37%), Query Frame = 1 
Query:   88 FFEQFEKASLFNSLITYLYFFILKCMGKLRDFMRNYGLEKNRLAVDSTKNKGFAPLYLDFEAFYTRNVYRRVCDCVNKPICSAPGGSLKAMNRVSDDHNWTFRILDSTSDIYNFGSYNYLGFAQNDGLCTDYVEKSINEFGLSVGSPRQEVGNTLYHLELEESLAEFLGQEAAIVFPMGFATNALNIPILVDKDCCVISDELNHVSLILGIRLSGADTRRFKHNNVESLERELIKAITEGHSKTKRKFKKILVVVEGVYSMEGSIVRLPEILELKKKYKFYIYLDEAHSIGALGKGGRGVVDYFNLNPHEVDIQMGTFTKSFASSGGYISGSRNLIHYVREKSHSTIYGGTMSGPICQQILSAMAIIGGKMGGSLGAERIRQLAWNTTYFRAALHRMGLIVFGNKNSPVIPVIVYTIPKVVAFHRECMRRGIGTVIVGYPACNLKLARIRFCISAAHTKRSLDYTLSIVDEIATHLRFKYSR 1533
            F E FE+  +  +++TY+ + +L   G LRDF R +G+E  + A +  + K F PLY DFE FYTRN+Y R+ D  N+PICS PG   K M RV+DD+NW FR      D+ N GSYNYLGFA+N G CT+   +   ++G+ V S RQE+GN   H ELE+ +A FLG EAA+ F MGFATN++NIP LV K C ++SDELNH SL+LG RLS A  R FKHN++ +LE+ L  AI  G  +T R +KKIL++VEG+YSMEGSIVRLPE++ LKK+YK Y+YLDEAHSIGA+G  GRGVV+YF L+P +VD+ MGTFTKSF + GGYI G ++L+ Y+R  SHS +Y  +MS PI +QIL +M  I G+ G +LGA+RIRQLA NT YFR  +  MG I +GN++SPV+PV++Y   K+ AF RE M+R IG V+VG+PA  +  +R RFCISAAHT+  LD TL+ VDEI   L+ KYSR
Sbjct:    7 FRETFEETPMLVAVLTYMGYGVLTLFGYLRDFFRAWGIESCQNATEREEQKDFVPLYQDFENFYTRNLYMRIRDNWNRPICSVPGSRFKVMERVTDDYNWNFRFTGRVKDVINMGSYNYLGFAENVGPCTEAAAQVAQKYGVGVCSTRQEMGNLDKHEELEKLVARFLGVEAAMAFGMGFATNSMNIPALVGKGCLILSDELNHASLVLGARLSTATIRVFKHNDMVNLEKLLRDAIVNGQPRTHRPWKKILILVEGIYSMEGSIVRLPEVVALKKRYKAYLYLDEAHSIGAVGPTGRGVVEYFGLHPQDVDVLMGTFTKSFGACGGYIGGRKDLVDYLRMNSHSAVYATSMSPPIIEQILQSMKCIMGEDGTTLGAQRIRQLAENTRYFRRRIREMGFITYGNEDSPVVPVMLYMPAKIGAFGREMMKRNIGVVVVGFPATPIIESRARFCISAAHTREMLDETLAAVDEIGDILQLKYSR 488
[Close]
BLAST of Serine palmitoyltransferase 2 vs. Ensembl Sea Lamprey
Match: alas2 (aminolevulinate, delta-, synthase 2 [Source:NCBI gene;Acc:64607])

HSP 1 Score: 122.479 bits (306), Expect = 2.815e-31
Identity = 93/304 (30.59%), Postives = 148/304 (48.68%), Query Frame = 1 
Query:  490 KSINEFGLSVGSPRQEVGNTLYHLELEESLAEFLGQEAAIVFPMGFATN-------ALNIPILVD-KDCCVISDELNHVSLILGIRLSGADTRRFKHNNVESLERELIKAITEGHSKTKRKFKKILVVVEGVYSMEGSIVRLPEILELKKKYKFYIYLDEAHSIGALGKGGRGVVDYFNLNPHEVDIQMGTFTKSFASSGGYISGSRNLIHYVREKSHSTIYGGTMSGPICQQILSAMAIIGGKMGGSLGAERIRQLAWNTTYFRAALHRMGLIVFGNKNSPVIPVIVYTIPKVVAFHRECMRR 1377
            +++   G   G  R   G + +H+ELE+ LA   G++AA++F   F  N       A  +P+L   K C + SD  NH S+I+GIR S      F+HN+   LE E++K       ++     KI V  E V+SM+G++  L E+ ++  KY    ++DE H++G  G  G G+ D  N+  H++DI  GT  K+F   GGY++ + +LI  VR  +   I+   +   +    L ++ ++    G +L     R    N  Y R  L   GL V  +  S +IPV+V    K      E M +
Sbjct:    2 ETLKMHGAGAGGTRNISGTSRFHVELEKELASLHGKDAALLFTSCFVANDSTLFTLAKMLPVLPHVKGCEIYSDAGNHASMIMGIRNSHVPKFVFRHNDPAHLE-EVLK-------RSDPSTPKI-VAFETVHSMDGAVCPLEEMCDIAHKYGAITFVDEVHAVGLYGTNGGGIGDRDNVM-HKMDIITGTLGKAFGCVGGYVASTASLIDTVRSYAAGFIFTTALPPMVLAGALESVRVLRSAEGQALR----RSHQRNVKYMRQLLMDAGLPVI-HCPSHIIPVLVANAAKNTEISNELMAQ 290
[Close]
BLAST of Serine palmitoyltransferase 2 vs. Ensembl Sea Lamprey
Match: sptlc1 (serine palmitoyltransferase, long chain base subunit 1 [Source:ZFIN;Acc:ZDB-GENE-050522-61])

HSP 1 Score: 115.546 bits (288), Expect = 1.094e-27
Identity = 75/251 (29.88%), Postives = 132/251 (52.59%), Query Frame = 1 
Query:  394 RILDSTSDIYNFGSYNYLGFAQNDGLCTDYVEKSINEFGLSVGSPRQEVGNTLYHLELEESLAEFLGQEAAIVFPMGFATNALNIPILVDKDCCVISDELNHVSLILGIRLSGADTRRFKHNNVESLERELIKAITEGHSKTKR-KFKKILVVVEGVYSMEGSIVRLPEILELKKKYKFYIYLDEAHSIGALGKGGRGVVDYFNLNPHEVDIQMGTFTKSFASSGGYISGSRNLIHYVREKSHSTIYGGTM 1143
            +I+ +  +  N  S+N+LG   N  +    +E S+ ++G+    PR   G    HLELEE +A F+  E AI++  GF+T A  IP    +   +   +    ++  G++ S ++ + F+HN+V  LER L +   E     K+    +  +VVEG+Y+  G +  LP+++ LK +YK  I+L+E+ S G LG+ GRGV ++F +N  ++D+       + AS GG+  G   +I + R       +  ++
Sbjct:   93 KIVVNDKECINLASFNFLGLLSNKRVKKVALE-SLAKYGVGTCGPRGFYGTFDVHLELEEQIARFMRCEEAIIYAYGFSTIASAIPAYSKRGDIIYVSKAVCFAIQKGLQASRSNVKYFRHNDVADLERLLQQQQQEDRKNPKKASVVRRFLVVEGLYTNTGDVCPLPDLVRLKYQYKVRIFLEESLSFGVLGETGRGVTEHFGVNIDDIDLISANMENALASIGGFCCGRSFVIDHQRLSGQGYCFSASL 342
[Close]
BLAST of Serine palmitoyltransferase 2 vs. Ensembl Yeast
Match: LCB2 (Component of serine palmitoyltransferase; responsible along with Lcb1p for the first committed step in sphingolipid synthesis, which is the condensation of serine with palmitoyl-CoA to form 3-ketosphinganine [Source:SGD;Acc:S000002469])

HSP 1 Score: 409.068 bits (1050), Expect = 7.446e-137
Identity = 205/497 (41.25%), Postives = 311/497 (62.58%), Query Frame = 1 
Query:   34 SNGHIKSIKQETKCKESEFFEQFEKASLFNSLITYLYFFILKCMGKLRDFMRNYGLEKNRLAVDSTKNKGFAPLYLDFEAFYTRNVYRRVCDCVNKPICSAPGGSLKAMNRVSDDHNWTFRILDSTSDIYNFGSYNYLGFAQNDGLCTDYVEKSINEFGLSVGSPRQEVGNTLYHLELEESLAEFLGQEAAIVFPMGFATNALNIPILVDKDCCVISDELNHVSLILGIRLSGADTRRFKHNNVESLERELIKAITEGHSKTKRKFKKILVVVEGVYSMEGSIVRLPEILELKKKYKFYIYLDEAHSIGALGKGGRGVVDYFNLNPHEVDIQMGTFTKSFASSGGYISGSRNLIHYVREKSHSTIYGGTMSGPICQQILSAMAIIGGKMGGSLGAERIRQLAWNTTYFRAALHRMGLIVFGNKNSPVIPVIVYTIPKVVAFHRECMRRGIGTVIVGYPACNLKLARIRFCISAAHTKRSLDYTLSIVDEIATHLRFK 1524
            S GH+  +K        E     +    + SL+TYL + IL  +G + DF+     +KN+  +D  ++ G AP + +FE+FY R +  R+ DC ++P    PG  ++ ++R+S + N  F    +     N  SYNYLGFAQ+ G CTD   +S++++ +  G PR ++G T  H++ E+ +A F+G+E A+VF MG+ TNA      +DK C VISDELNH S+  G+RLSGA  R FKH ++  LE+ + + I  G  KT R +KKIL+  EG++SMEG++  LP+++ELKKKYK Y+++DEAHSIGA+G  GRGV + F ++P +VDI MGTFTKSF ++GGYI+  + +I  +R    +  Y  +M  P+  Q +S++  I G++    G ER++++A+N+ Y R AL R+G IV+G  +SPVIP+++Y   K+ AF R  ++R I  V+V YPA  L  +R+RFC+SA+ TK  +DY L  V E+   L  K
Sbjct:   33 SPGHLYQVKSRHGKPLPE--PVVDTPPYYISLLTYLNYLILIILGHVHDFL-GMTFQKNK-HLDLLEHDGLAPWFSNFESFYVRRIKMRIDDCFSRPTTGVPGRFIRCIDRISHNINEYFTYSGAVYPCMNLSSYNYLGFAQSKGQCTDAALESVDKYSIQSGGPRAQIGTTDLHIKAEKLVARFIGKEDALVFSMGYGTNANLFNAFLDKKCLVISDELNHTSIRTGVRLSGAAVRTFKHGDMVGLEKLIREQIVLGQPKTNRPWKKILICAEGLFSMEGTLCNLPKLVELKKKYKCYLFIDEAHSIGAMGPTGRGVCEIFGVDPKDVDILMGTFTKSFGAAGGYIAADQWIIDRLRLDLTTVSYSESMPAPVLAQTISSLQTISGEICPGQGTERLQRIAFNSRYLRLALQRLGFIVYGVADSPVIPLLLYCPSKMPAFSRMMLQRRIAVVVVAYPATPLIESRVRFCMSASLTKEDIDYLLRHVSEVGDKLNLK 525
[Close]
BLAST of Serine palmitoyltransferase 2 vs. Ensembl Yeast
Match: HEM1 (5-aminolevulinate synthase; catalyzes the first step in the heme biosynthetic pathway; an N-terminal signal sequence is required for localization to the mitochondrial matrix; expression is regulated by Hap2p-Hap3p; has a pyridoxal phosphate cofactor whose insertion is mediated by Mcx1p [Source:SGD;Acc:S000002640])

HSP 1 Score: 139.813 bits (351), Expect = 9.271e-36
Identity = 109/413 (26.39%), Postives = 181/413 (43.83%), Query Frame = 1 
Query:  433 SYNYLGFAQNDGLCTDYVEKSINEFGLSVGSPRQEVGNTLYHLELEESLAEFLGQEAAIVFPMGFATNALNIPILVDK--DCCVISDELNHVSLILGIRLSGADTRRFKHNNVESLERELIKAITEGHSKTKRKFKKILVVVEGVYSMEGSIVRLPEILELKKKYKFYIYLDEAHSIGALGKGGRGVVDYFNLNPH---------------------EVDIQMGTFTKSFASSGGYISGSRNLIHYVREKSHSTIYGGTMSGPICQQILSAMAIIGGKMGGSLGAERIRQLAWN--------TTYFRAALHRMGLIVFGNKNSPVIPVIVYTIPKVVAFHRECMRRGIGTVI---------VGYPACNLKLARIRFCISAAHTKRSLDYTLSIVDEIATHLRFKYSRLPVPDW 1551
            S +YL  +++  +  D + K+I+++G   G  R   G+ +  L LE  LA    +E A+VF   +  N   + +L  K  D  + SDELNH S+I+GI+ +      FKHN++  LE+ L     + + K+  K    L+  E VYSM GS+  + +I +L  KY    +LDE H++G  G  G GV ++ +   H                      VD+  GT  KSF S GGY++ SR LI + R  +   I+  T+   +              M G+  A R ++   +        T Y + A H +G+        PVIP   + +P ++  + +  ++    +I         + +P       R+R   +  HT    D  ++ VD++   L+    R    DW
Sbjct:  120 SNDYLALSKHPEVL-DAMHKTIDKYGCGAGGTRNIAGHNIPTLNLEAELATLHKKEGALVFSSCYVANDAVLSLLGQKMKDLVIFSDELNHASMIVGIKHANVKKHIFKHNDLNELEQLL-----QSYPKSVPK----LIAFESVYSMAGSVADIEKICDLADKYGALTFLDEVHAVGLYGPHGAGVAEHCDFESHRASGIATPKTNDKGGAKTVMDRVDMITGTLGKSFGSVGGYVAASRKLIDWFRSFAPGFIFTTTLPPSV--------------MAGATAAIRYQRCHIDLRTSQQKHTMYVKKAFHELGI--------PVIPNPSHIVPVLIG-NADLAKQASDILINKHQIYVQAINFPTVARGTERLRITPTPGHTNDLSDILINAVDDVFNELQLPRVR----DW 495
[Close]
BLAST of Serine palmitoyltransferase 2 vs. Ensembl Yeast
Match: LCB1 (Component of serine palmitoyltransferase; responsible along with Lcb2p for the first committed step in sphingolipid synthesis, which is the condensation of serine with palmitoyl-CoA to form 3-ketosphinganine [Source:SGD;Acc:S000004911])

HSP 1 Score: 117.857 bits (294), Expect = 2.321e-28
Identity = 69/252 (27.38%), Postives = 130/252 (51.59%), Query Frame = 1 
Query:  412 SDIYNFGSYNYLGFAQNDGLCTDYVEKSINEFGLSVGSPRQEVGNTLYHLELEESLAEFLGQEAAIVFPMGFATNALNIPILVDKDCCVISDELNHVSLILGIRLSGADTRRFKHNNVESLERELIKAITEGHSKTK-----RKFKKILVVVEGVYSMEGSIVRLPEILELKKKYKFYIYLDEAHSIGALGKGGRGVVDYFNLN-PHEVDIQMGTFTKSFASSGGYISGSRNLIHYVREKSHSTIYGGTMSG 1149
            ++++N  S N+L  +  + +  + V+ +I  +G+    P    GN   H  LE  LA+F G + ++++   F      +P    +   +++D+   + +   ++LS +    F HN++ SLE  L+  +TE     K     RKF    +V EG++   G +  LPE+ +LK KYKF +++DE  SIG LG  GRG+ ++FN++    +DI +G+   +  S+GG++ G   +  + R  S++  +   +  
Sbjct:  145 TNVFNLASNNFLQLSATEPV-KEVVKTTIKNYGVGACGPAGFYGNQDVHYTLEYDLAQFFGTQGSVLYGQDFCAAPSVLPAFTKRGDVIVADDQVSLPVQNALQLSRSTVYYFNHNDMNSLEC-LLNELTEQEKLEKLPAIPRKF----IVTEGIFHNSGDLAPLPELTKLKNKYKFRLFVDETFSIGVLGATGRGLSEHFNMDRATAIDITVGSMATALGSTGGFVLGDSVMCLHQRIGSNAYCFSACLPA 390
[Close]
BLAST of Serine palmitoyltransferase 2 vs. Ensembl Nematostella
Match: EDO42990 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RZR1])

HSP 1 Score: 557.755 bits (1436), Expect = 0.000e+0
Identity = 261/499 (52.30%), Postives = 363/499 (72.75%), Query Frame = 1 
Query:   37 NGHIKSIKQETKCKESEFFEQFEKASLFNSLITYLYFFILKCMGKLRDFMRNYGLEKNRLAVDSTKNKGFAPLYLDFEAFYTRNVYRRVCDCVNKPICSAPGGSLKAMNRVSDDHNWTFRILDSTSDIYNFGSYNYLGFAQNDGLCTDYVEKSINEFGLSVGSPRQEVGNTLYHLELEESLAEFLGQEAAIVFPMGFATNALNIPILVDKDCCVISDELNHVSLILGIRLSGADTRRFKHNNVESLERELIKAITEGHSKTKRKFKKILVVVEGVYSMEGSIVRLPEILELKKKYKFYIYLDEAHSIGALGKGGRGVVDYFNLNPHEVDIQMGTFTKSFASSGGYISGSRNLIHYVREKSHSTIYGGTMSGPICQQILSAMAIIGGKMGGSLGAERIRQLAWNTTYFRAALHRMGLIVFGNKNSPVIPVIVYTIPKVVAFHRECMRRGIGTVIVGYPACNLKLARIRFCISAAHTKRSLDYTLSIVDEIATHLRFKYSR 1533
            NGHI +       K  EF E+FE+  L  +++TY+ +F+L   G +RDFMR +GLEK++ A +   NKGF PLY DFE+FYTRN+Y R+ DC N+PICS PG  ++ ++RVSDD+ WTF    + +   N GSYNYLGFA+N+GLC D  EKS+++ G++V S R E G    H+ELE+ +A F+G+E+A+VF MGFATN+ NIP+LV K   +ISDELNH SL+LG RLSGA  + FKHN+++SLE +L  ++ +G  +T R ++KIL++VEGVYSMEGS+VRLPEI+ +KKKYK Y+YLDEAHSIGA+G  GRGV +YF +NP ++DI MGTFTKSF ++GGYI+ S+ +I+++R  SHS  Y  +MS P+  QI ++M II G+ G +LG +RI+ LA NT YFR  L  +G I++G+  SPV+P+++Y   K+ AF RE ++R IG V+VG+PA  +  +R RFC+SAAHT+  LD  L+ +DE+   L+ KYSR
Sbjct:   26 NGHIPNGIPHKGSKVKEFHEEFEETPLIVAVLTYIGYFVLVVFGYMRDFMRKHGLEKSKTAKEKG-NKGFVPLYADFESFYTRNLYTRIRDCWNRPICSVPGAQIELVDRVSDDYGWTFNFTGTKTKALNLGSYNYLGFAENEGLCADEAEKSVHKNGIAVCSARHEFGTLDIHIELEKMVARFVGKESAMVFGMGFATNSTNIPVLVSKGDLIISDELNHSSLVLGARLSGATIKVFKHNDIKSLENKLRTSVVQGQPRTHRPWRKILIIVEGVYSMEGSLVRLPEIVAIKKKYKAYLYLDEAHSIGAVGPTGRGVSEYFGVNPADIDIMMGTFTKSFGAAGGYIASSKEIINHIRGCSHSAAYASSMSPPVTLQIYTSMKIILGEDGTNLGKQRIQALAENTRYFRCRLKELGFIIYGHDESPVVPLLLYMPAKIAAFGREMLKRKIGVVVVGFPATPIIESRARFCLSAAHTREMLDQALAAIDEVGDILQLKYSR 523
[Close]
BLAST of Serine palmitoyltransferase 2 vs. Ensembl Nematostella
Match: EDO27220 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T9V2])

HSP 1 Score: 181.8 bits (460), Expect = 1.627e-51
Identity = 114/369 (30.89%), Postives = 197/369 (53.39%), Query Frame = 1 
Query:  418 IYNFGSYNYLGFAQNDGLCTDYVEKSINEFGLSVGSPRQEVGNTLYHLELEESLAEFLGQEAAIVFPMGFATNA-LNIPILVDKDCCVISDELNHVSLILGIRLSGADTRRFKHNNVESLERELIKAITEGHSKTKRKFKKILVVVEGVYSMEGSIVRLPEILELKKKYKFYIYLDEAHSIGALGKGGRGVVDYFNLNPHEVDIQMGTFTKSFASS-GGYISGSRNLIHYVREKSHSTIYGGTMSGPICQQILSAMAIIGGKMGGSLGAERIRQLAWNTTYFRAALHRMGLIVFGNKNSPVIPVIVYTIPKVVAFHRECMRRGIGTVIVGYPACNLKLARIRFCISAAHTKRSLDYTLSIVDEIATHLR 1518
            + NF + NYLG + +  +     + +++  G  + S R   G    H ELE+ +A+F G E  I++   F  N  +  P+L ++DC +ISD LNH S+I G+RL  A   R+++N++  LE +LIKA   GH     +FK  L+V +GV+SM+G +  L +I +L  KY+  + +DE H+ G +G  G+G ++  N+    VDI  GTF K+   + GGY +  + +I  +R++S   ++  +++  I    L    ++  +   SL      +L WNT YF+  + + G  +  + ++ ++PV++Y          E +++GI  +   +P    + ARIR  +SAAHTK  LD  +    E+   L+
Sbjct:   37 VLNFCANNYLGLSSHPEVVQ-AAKDALDSHGFGMSSVRFICGTQDIHKELEQKVAQFYGTEDTILYAAAFDANGGVFEPLLGEQDC-IISDSLNHASIIDGVRLCKAARYRYQNNDMNDLEAQLIKATEAGH-----RFK--LIVTDGVFSMDGLVAPLDKICDLADKYEAMVMVDECHAAGFIGATGKGTLEAKNVMGR-VDIITGTFGKALGGAMGGYTTAKKEIIEILRQRSRPYLFSNSLAPSIVGASLKVFELL--EKDTSLR----DKLEWNTNYFKEGMKKAGFDII-DGDAAIVPVMLYDAKLSQTMAEELLKKGIYVIGFFFPVVPKEKARIRVQLSAAHTKEHLDIAIKAFVEVGKSLK 388
[Close]
BLAST of Serine palmitoyltransferase 2 vs. Ensembl Nematostella
Match: EDO38490 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SCT4])

HSP 1 Score: 158.303 bits (399), Expect = 1.061e-42
Identity = 114/356 (32.02%), Postives = 180/356 (50.56%), Query Frame = 1 
Query:  412 SDIYNFGSYNYLGFAQNDGLCTDYVEKSINEFGLSVGSPRQEVGNTLYHLELEESLAEFLGQEAAIVFPMGFATNALNIPILVDKDCCVISDELNHVSLILGIRLSGADTRRFKHNNVESLERELIKAITEGHSKTKRKFKKILVVVEGVYSMEGSIVRLPEILELKKKYKFYIYLDEAHSIGALGKGGRGVVDYFNLNPHEVDIQMGTFTKSFASSGGYISGSRNLIHYVREKSHSTIYGGTMSGPICQQILSAMAIIGGKMGGSLGAERIRQLAWNTTYFRAALHRMGLIVFGNKNS-PVIPVIVYTIPKVVAFHRECMRRGIGTVIVGYPACNLKLARIRFCISAAHTKRSLD 1476
            S I NF + NYLG + N     +  ++++ ++G  + S R   G    H  LE  +++F G E AI++   +  N      L+  +  V SDELNH S+I GIRL  A   ++KH +V+ LE +L +A     ++ K      L+  +GV+SM+GS+  LPEI +L  KY   +++DE H+ G LG  GRG  +Y         I          ++GGY +G   L+  +R+KS   +Y  T+   +   + SA  ++   M GS   E  ++LA NT+YFR  + + G  + G  N  P+ P+++      + F  E + RGI  V + YP       RIR  +SA H+K  +D
Sbjct:   56 SKILNFCANNYLGLSSN-AEVVNAAKEALMKYGNGLSSVRFICGTQDIHKTLEAKISKFHGMEDAILYACCYDANTGLFESLLTAEDAVFSDELNHASMIDGIRLCRAKKFKYKHIDVQDLEEKLKEA---DGARIK------LIASDGVFSMDGSMAPLPEICDLADKYGALVFIDECHATGFLGDTGRGTDEYTGTRGRVDIINSTLGKALGGAAGGYTTGPSQLVQMLRQKSRPYLYSNTLPPAV---VGSATKVLDMLMDGS---ELSKKLADNTSYFRTKMTQAGFNIKGGANGHPITPIMLGDSKLAMDFANEMLERGIYVVGIVYPTVPRGTGRIRVQLSAGHSKEEID 395
[Close]
BLAST of Serine palmitoyltransferase 2 vs. Ensembl Nematostella
Match: EDO46206 (5-aminolevulinate synthase [Source:UniProtKB/TrEMBL;Acc:A7RQQ4])

HSP 1 Score: 119.398 bits (298), Expect = 1.386e-28
Identity = 109/449 (24.28%), Postives = 194/449 (43.21%), Query Frame = 1 
Query:  172 LRDFMRNYGLEKNRLAVDSTKNKGFAPLYLDFEAFYTRNVYRRVCDCVNKPICSAPGGSLKAMNRVSD--DHNWTFRILDSTSDIYNFGSYNYLGFAQNDGLCTDYVEKSINEFGLSVGSPRQEVGNTLYHLELEESLAEFLGQEAAIVFPMGFATNALNIPILVD--KDCCVISDELNHVSLILGIRLSGADTRRFKHNNVESLERELIKAITEGHSKTKRKFKKILVVVEGVYSMEGSIVRLPEILELKKKYKFYIYLDEAHSIGALGKGGRGVVDYFNLNPHEVDIQMGTFTKSFASSGGYISGSRNLIHYVREKSHSTIYGGTMSGPICQQILSAMAIIGGKMGGSLGAERIRQLAWNTTYFRAALHRMGLIVFGNKNSPVIPVIVYTIPKVVAFHRECM-RRGIGTVIVGYPACNLKLARIRFCISAAHTKRSLDYTLSIVDEI 1503
             R  ++N     + +++     K     + ++E F+   + ++  D   +          K +NR++    H   F    +  DI  + S +YLG +++  +      ++I+  G+  G  R   G + YH +LE+ LA+   +EAA++F   +  N   +  L      C + SD  NH S+I GIR SGA    F+HN+ E L +                    +V  E V+SM G I  + ++ ++  KY    ++DE H++G  G  G GV +   L   ++DI  GT  K+F   GGYI+G+ +LI  +R      I+   +     +  + ++ I+ G  G  L   R+ Q        R  L + GL V     S +IP+ V    K      + M +  I    + YP       R+R   +  HT+  +++   ++ ++
Sbjct:   67 FRCTLKNIHCRADEVSIAIFVEKKMHQAHFEYEKFFEGEIQKKKADDTYR--------VFKKVNRLAKAFPHAQEFSGA-ANKDISVWCSNDYLGMSRHPEV-LKVARETIDVHGVGAGGTRNISGTSSYHEQLEKVLAQLHQKEAALLFTSCYVANDTTLYTLGKHLPGCLIFSDAGNHASMIQGIRNSGAKKFIFRHNDPEHLGKL---------LAAADPAAPKIVAFETVHSMTGDISPIKQLCDVAHKYGALTFVDEVHAVGLYGHHGGGVGERDGLLA-DMDIISGTLGKAFGVIGGYIAGTASLIDTIRSYGAGFIFTTALPPITVKSAIKSIEILSGDEGRDL--RRVHQSV--VARLRNKLVQRGLPVV-YAPSHIIPIHVGDAGKCTQVSNDLMSKHNIYAQAINYPTVAKGEERLRIAPTPMHTEPMMEHFADVLTQV 490
[Close]
BLAST of Serine palmitoyltransferase 2 vs. Ensembl Nematostella
Match: EDO36082 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SJP9])

HSP 1 Score: 118.627 bits (296), Expect = 1.446e-28
Identity = 91/301 (30.23%), Postives = 156/301 (51.83%), Query Frame = 1 
Query:  424 NFGSYNYLGFAQNDGLCTDYVEKSINEFGLSVGSPRQEVGNTLYHLELEESLAEFLGQEAAIVFPMGFATNALNIPILVDKDCCVISDELNHVSLILGIRLSGADTRRFKHNNVESLERELIKAITEGHSKTKRK--FKKILVVVEGVYSMEGSIVRLPEILELKKKYKFYIYLDEAHSIGALGKGGRGVVDYFNLNPHEVDIQMGTFTKSFASSGGYISGSRNLIHYVREKSHSTIYGGTMSGPICQQILSAMAIIGGKMGGSLGAERIRQLAWNTTYFRAALHRM-GLIVFGNKNSPVI 1317
            N  ++N+LGF  N  + +  ++ ++ ++G+    PR   G+   HL LEE LA+F+  E AI++  GF+T A  IP    +   +  D+    ++  G+  S +    F+HN+++ LER L+K   E   K  +K    +  ++VEG+Y   G+I  LP++LELKKKYK  I +DE+ S G LGK GRGV +Y+++   +VD+   +   S A+ GG+  G+  ++ + R       +  ++   +    + A+ I+  K G          L      F   L  + GL + G ++SP+I
Sbjct:   97 NLATFNFLGFVGNPRIESSAID-TLRKYGVGSCGPRGFYGSIDVHLHLEERLAKFMHTEEAILYSYGFSTVASAIPAYSKRGDVLFCDKGVCFAIQQGVTASRSRVMWFEHNDMDDLER-LLKEQQEKDRKNPKKGSVTRRFLIVEGLYINHGTIAPLPKLLELKKKYKVRILVDESCSFGVLGKTGRGVTEYYDIPVDDVDLISVSMENSLATIGGFCCGTSFVVDHQRLSGAGYCFSASLPPMLATAAIEALDIMEEKDG------MFNDLQMKARLFHQELKGIKGLRIDGERDSPII 389
[Close]
BLAST of Serine palmitoyltransferase 2 vs. Ensembl Medaka
Match: ENSORLT00000022091.2 (serine palmitoyltransferase 2-like [Source:NCBI gene;Acc:101156930])

HSP 1 Score: 549.28 bits (1414), Expect = 0.000e+0
Identity = 267/520 (51.35%), Postives = 359/520 (69.04%), Query Frame = 1 
Query:   58 KQETKCKESEFFEQFEKASLFNSLITYLYFFILKCMGKLRDFMRNYGLEKNRLAVDSTKNKGFAPLYLDFEAFYTRNVYRRVCDCVNKPICSAPGGSLKAMNRVSDDHNWTFRILDST-SDIYNFGSYNYLGFAQNDGLCTDYVEKSINEFGLSVGSPRQEVGNTLYHLELEESLAEFLGQEAAIVFPMGFATNALNIPILVDKDCCVISDELNHVSLILGIRLSGADTRRFKHNNVESLERELIKAITEGHSKTKRKFKKILVVVEGVYSMEGSIVRLPEILELKKKYKFYIYLDEAHSIGALGKGGRGVVDYFNLNPHEVDIQMGTFTKSFASSGGYISGSRNLIHYVREKSHSTIYGGTMSGPICQQILSAMAIIGGKMGGSLGAERIRQLAWNTTYFRAALHRMGLIVFGNKNSPVIPVIVYTIPKVVAFHRECMRRGIGTVIVGYPACNLKLARIRFCISAAHTKRSLDYTLSIVDEIATHLRFKYSRLPVPDWCKNVPQRSLIFNENKCCDKYD 1614
            ++E       F E FE+  +  +++T + + IL   G LRD +R++ +E+  +A +  + K F PLY DF+ FYTRN+Y R+ D  N+PICS PG  +  M+R S D+NWTF     T  D+ N GSYNYLGFA+N G C D   + +  +G+ V S RQE+GN   H E+E+ +A+FLG E+A+ F MGFATN++NIP LV K C ++SDELNH SL+LG RLSGA  R FKHNN++ LE+ L +AI  G  +T R +KKIL+VVEG+YSMEGSIVRLPE++ LKK+YK Y+YLDEAHSIGALG  GRGVVDYF+L+P +VD+ MGTFTKSF ++GGYI+G R LI Y+R  SHS +Y  +MS P+ +QI+++M  I G  G S+G +R++QLA NTTYFR  L  MG I++GN +SPVIP+++Y   K+ AF RE +++ IG V+VG+PA +L  +R RFCISAAH+K  LD  LS + E+   L+ KYSR       +N P   L F EN   D  D
Sbjct:   12 RREEDLYSRPFTESFEETPMLVAVLTNVGYVILIIFGYLRDLLRHWKIEQRHIAREKEEQKDFVPLYRDFQNFYTRNLYMRIRDNWNRPICSVPGAKMDLMDRTSHDYNWTFEYNGRTMKDVINLGSYNYLGFAENTGPCADSAAQVVRTYGIGVASTRQEIGNLDKHEEMEKQVAKFLGVESAMAFGMGFATNSMNIPALVGKGCLILSDELNHTSLVLGARLSGATIRVFKHNNMQCLEKLLSEAIIYGQPRTHRPWKKILIVVEGIYSMEGSIVRLPEVITLKKRYKAYLYLDEAHSIGALGHRGRGVVDYFDLDPRDVDVLMGTFTKSFGAAGGYIAGKRELIEYLRSHSHSAVYAASMSPPVVEQIITSMKCIMGDDGTSIGCKRLQQLAENTTYFRRRLREMGFIIYGNDDSPVIPMMLYMPAKIGAFGREMLKKNIGVVVVGFPATSLVESRARFCISAAHSKEILDTALSAISEVGDVLQLKYSR----RLTQNAPSAHL-FAENMFEDIDD 526
[Close]
BLAST of Serine palmitoyltransferase 2 vs. Ensembl Medaka
Match: ENSORLT00000042858.1 (serine palmitoyltransferase 2-like [Source:NCBI gene;Acc:101156930])

HSP 1 Score: 548.895 bits (1413), Expect = 0.000e+0
Identity = 266/510 (52.16%), Postives = 356/510 (69.80%), Query Frame = 1 
Query:   88 FFEQFEKASLFNSLITYLYFFILKCMGKLRDFMRNYGLEKNRLAVDSTKNKGFAPLYLDFEAFYTRNVYRRVCDCVNKPICSAPGGSLKAMNRVSDDHNWTFRILDST-SDIYNFGSYNYLGFAQNDGLCTDYVEKSINEFGLSVGSPRQEVGNTLYHLELEESLAEFLGQEAAIVFPMGFATNALNIPILVDKDCCVISDELNHVSLILGIRLSGADTRRFKHNNVESLERELIKAITEGHSKTKRKFKKILVVVEGVYSMEGSIVRLPEILELKKKYKFYIYLDEAHSIGALGKGGRGVVDYFNLNPHEVDIQMGTFTKSFASSGGYISGSRNLIHYVREKSHSTIYGGTMSGPICQQILSAMAIIGGKMGGSLGAERIRQLAWNTTYFRAALHRMGLIVFGNKNSPVIPVIVYTIPKVVAFHRECMRRGIGTVIVGYPACNLKLARIRFCISAAHTKRSLDYTLSIVDEIATHLRFKYSRLPVPDWCKNVPQRSLIFNENKCCDKYD 1614
            F E FE+  +  +++T + + IL   G LRD +R++ +E+  +A +  + K F PLY DF+ FYTRN+Y R+ D  N+PICS PG  +  M+R S D+NWTF     T  D+ N GSYNYLGFA+N G C D   + +  +G+ V S RQE+GN   H E+E+ +A+FLG E+A+ F MGFATN++NIP LV K C ++SDELNH SL+LG RLSGA  R FKHNN++ LE+ L +AI  G  +T R +KKIL+VVEG+YSMEGSIVRLPE++ LKK+YK Y+YLDEAHSIGALG  GRGVVDYF+L+P +VD+ MGTFTKSF ++GGYI+G R LI Y+R  SHS +Y  +MS P+ +QI+++M  I G  G S+G +R++QLA NTTYFR  L  MG I++GN +SPVIP+++Y   K+ AF RE +++ IG V+VG+PA +L  +R RFCISAAH+K  LD  LS + E+   L+ KYSR       +N P   L F EN   D  D
Sbjct:   70 FTESFEETPMLVAVLTNVGYVILIIFGYLRDLLRHWKIEQRHIAREKEEQKDFVPLYRDFQNFYTRNLYMRIRDNWNRPICSVPGAKMDLMDRTSHDYNWTFEYNGRTMKDVINLGSYNYLGFAENTGPCADSAAQVVRTYGIGVASTRQEIGNLDKHEEMEKQVAKFLGVESAMAFGMGFATNSMNIPALVGKGCLILSDELNHTSLVLGARLSGATIRVFKHNNMQCLEKLLSEAIIYGQPRTHRPWKKILIVVEGIYSMEGSIVRLPEVITLKKRYKAYLYLDEAHSIGALGHRGRGVVDYFDLDPRDVDVLMGTFTKSFGAAGGYIAGKRELIEYLRSHSHSAVYAASMSPPVVEQIITSMKCIMGDDGTSIGCKRLQQLAENTTYFRRRLREMGFIIYGNDDSPVIPMMLYMPAKIGAFGREMLKKNIGVVVVGFPATSLVESRARFCISAAHSKEILDTALSAISEVGDVLQLKYSR----RLTQNAPSAHL-FAENMFEDIDD 574
[Close]
BLAST of Serine palmitoyltransferase 2 vs. Ensembl Medaka
Match: sptlc2b (serine palmitoyltransferase 2 [Source:NCBI gene;Acc:101165525])

HSP 1 Score: 543.117 bits (1398), Expect = 0.000e+0
Identity = 260/493 (52.74%), Postives = 346/493 (70.18%), Query Frame = 1 
Query:   88 FFEQFEKASLFNSLITYLYFFILKCMGKLRDFMRNYGLEKNRLAVDSTKNKGFAPLYLDFEAFYTRNVYRRVCDCVNKPICSAPGGSLKAMNRVSDDHNWTFRILDST-SDIYNFGSYNYLGFAQNDGLCTDYVEKSINEFGLSVGSPRQEVGNTLYHLELEESLAEFLGQEAAIVFPMGFATNALNIPILVDKDCCVISDELNHVSLILGIRLSGADTRRFKHNNVESLERELIKAITEGHSKTKRKFKKILVVVEGVYSMEGSIVRLPEILELKKKYKFYIYLDEAHSIGALGKGGRGVVDYFNLNPHEVDIQMGTFTKSFASSGGYISGSRNLIHYVREKSHSTIYGGTMSGPICQQILSAMAIIGGKMGGSLGAERIRQLAWNTTYFRAALHRMGLIVFGNKNSPVIPVIVYTIPKVVAFHRECMRRGIGTVIVGYPACNLKLARIRFCISAAHTKRSLDYTLSIVDEIATHLRFKYSR----LPVPDW 1551
            F E FE+  L  +++TY+ + IL   G  RDF+R++ +EK  +A +  + K F PLY DFE FYTRN+Y R+ D  N+PICS PG  +  + RV+ ++NWTF        D+ N GSYNYLGFA+N G C     ++ + +G+ V S R E+GN   H ELE+ +A FLG E+++ F MGFATN++NIP L  K C ++SDELNH SL+LG RLSG+  R FKHNN++SLE+ L  AI  G  +T R +KKIL+VVEG+YSMEGSIVRLPE++ LKK+YK Y+YLDEAHSIGALG  GRGVVDYF L+P +VDI MGTFTKSF ++GGYI G + LI Y+R  SHS +Y  +MS P+ QQI+S+M II G+ G +LG +R+RQL+ NTTYFR  L  MG I++GN +SPV+P+++Y   K+ AF RE ++R IGTV+VG+PA  +  +R RFC+SAAHT+  LD  L  + E+   L+ KYSR    L  P W
Sbjct:   63 FSESFEETPLLVAVLTYMGYGILTIFGYFRDFLRHWNIEKCHIAHEREQQKDFVPLYQDFENFYTRNLYMRIRDNWNRPICSVPGAKVDLVERVTHNYNWTFEHTGKVVKDVINMGSYNYLGFAENTGACASAAIETTHAYGVGVASTRCEIGNLDIHEELEQLVARFLGVESSMAFGMGFATNSMNIPPLTGKGCLILSDELNHASLVLGARLSGSTIRVFKHNNMQSLEKLLRDAIAHGQPRTHRPWKKILIVVEGIYSMEGSIVRLPEVIALKKRYKAYLYLDEAHSIGALGPNGRGVVDYFGLDPKDVDIMMGTFTKSFGAAGGYIGGRKELIDYLRCHSHSALYATSMSPPVAQQIISSMKIIMGEDGSTLGKDRLRQLSENTTYFRRKLREMGFIIYGNDDSPVVPLMLYMPAKIGAFGREMLKRNIGTVVVGFPATPIIESRARFCVSAAHTREMLDTALRAISEVGDLLQLKYSRRERPLSTPGW 555
[Close]
BLAST of Serine palmitoyltransferase 2 vs. Ensembl Medaka
Match: sptlc3 (serine palmitoyltransferase long chain base subunit 3 [Source:NCBI gene;Acc:101166657])

HSP 1 Score: 533.872 bits (1374), Expect = 0.000e+0
Identity = 264/492 (53.66%), Postives = 343/492 (69.72%), Query Frame = 1 
Query:   94 EQFEKASLFNSLITYLYFFILKCMGKLRDFMRNYGLEKNRLAVDSTKNKGFAPLYLDFEAFYTRNVYRRVCDCVNKPICSAPGGSLKAMNRVSDDHNWTFRILDST-SDIYNFGSYNYLGFAQNDGLCTDYVEKSINEFGLSVGSPRQEVGNTLYHLELEESLAEFLGQEAAIVFPMGFATNALNIPILVDKDCCVISDELNHVSLILGIRLSGADTRRFKHNNVESLERELIKAITEGHSKTKRKFKKILVVVEGVYSMEGSIVRLPEILELKKKYKFYIYLDEAHSIGALGKGGRGVVDYFNLNPHEVDIQMGTFTKSFASSGGYISGSRNLIHYVREKSHSTIYGGTMSGPICQQILSAMAIIGGKMGGSLGAERIRQLAWNTTYFRAALHRMGLIVFGNKNSPVIPVIVYTIPKVVAFHRECMRRGIGTVIVGYPACNLKLARIRFCISAAHTKRSLDYTLSIVDEIATHLRFKYSRLPVP---DWCK 1557
            E FE+A ++ ++ TY+ F I+   G  RDF+R  GLEK  LA +  + K F PLY DFE FYTRN+Y RV D  N+PICS PG     M RVSDD+NWTFR    T  ++ N GSYNYLGFA+N+      V   + ++G  V S RQE+GN   H ELE+ +A FLG E+A+ + MGFATN++NIP LV K C ++SDELNH SLILG RLSGA  R FKHNN+ SLE+ L +AI  G  +T R ++KIL++VEG+YSMEGS+VRLPE++ LKKKYK ++YLDEAHSIGA+G  GRGV + F++NP +VD+ MGTFTKSF +SGGYI+G + L+ Y+R  SHS +Y   MS P+ +QI+ A+  I GK G + G  RIRQLA NT YFRA L  MG I++GN +SPVIPV++Y   KVVAF RE ++R IG V+VG+PA  +  AR RFC+SAAHT+  L+  L  ++E+   L  K+SR   P   D C+
Sbjct:   50 ESFEQAPMYVAVCTYMGFGIVTLFGYFRDFLRAVGLEKCNLAQEREEQKDFVPLYQDFENFYTRNLYMRVRDNWNRPICSLPGPVFDLMERVSDDYNWTFRFTGRTIPNVINMGSYNYLGFAENNADFLKTVADKVQQYGAGVCSTRQEIGNLSIHEELEQLVANFLGVESAMTYGMGFATNSMNIPALVGKGCLILSDELNHTSLILGARLSGATIRVFKHNNMHSLEKMLKEAICCGQPRTHRAWRKILIMVEGIYSMEGSVVRLPEVIALKKKYKAHLYLDEAHSIGAVGATGRGVTELFHVNPADVDVMMGTFTKSFGASGGYIAGKKELVDYLRSHSHSAVYASAMSPPVTEQIIRAIKCIMGKDGTTEGIRRIRQLAENTRYFRARLKEMGFIIYGNDDSPVIPVLLYMPGKVVAFAREMLQRKIGVVVVGFPATPITEARARFCLSAAHTRAMLNQVLQHLNEVGDLLCLKFSRRKRPSSLDLCE 541
[Close]
BLAST of Serine palmitoyltransferase 2 vs. Ensembl Medaka
Match: ENSORLT00000013273.2 (serine palmitoyltransferase 2-like [Source:NCBI gene;Acc:101156930])

HSP 1 Score: 532.332 bits (1370), Expect = 0.000e+0
Identity = 251/468 (53.63%), Postives = 337/468 (72.01%), Query Frame = 1 
Query:   88 FFEQFEKASLFNSLITYLYFFILKCMGKLRDFMRNYGLEKNRLAVDSTKNKGFAPLYLDFEAFYTRNVYRRVCDCVNKPICSAPGGSLKAMNRVSDDHNWTFRILDST-SDIYNFGSYNYLGFAQNDGLCTDYVEKSINEFGLSVGSPRQEVGNTLYHLELEESLAEFLGQEAAIVFPMGFATNALNIPILVDKDCCVISDELNHVSLILGIRLSGADTRRFKHNNVESLERELIKAITEGHSKTKRKFKKILVVVEGVYSMEGSIVRLPEILELKKKYKFYIYLDEAHSIGALGKGGRGVVDYFNLNPHEVDIQMGTFTKSFASSGGYISGSRNLIHYVREKSHSTIYGGTMSGPICQQILSAMAIIGGKMGGSLGAERIRQLAWNTTYFRAALHRMGLIVFGNKNSPVIPVIVYTIPKVVAFHRECMRRGIGTVIVGYPACNLKLARIRFCISAAHTKRSLDYTLS 1488
            F E FE+  +  +++T + + IL   G LRD +R++ +E+  +A +  + K F PLY DF+ FYTRN+Y R+ D  N+PICS PG  +  M+R S D+NWTF     T  D+ N GSYNYLGFA+N G C D   + +  +G+ V S RQE+GN   H E+E+ +A+FLG E+A+ F MGFATN++NIP LV K C ++SDELNH SL+LG RLSGA  R FKHNN++ LE+ L +AI  G  +T R +KKIL+VVEG+YSMEGSIVRLPE++ LKK+YK Y+YLDEAHSIGALG  GRGVVDYF+L+P +VD+ MGTFTKSF ++GGYI+G R LI Y+R  SHS +Y  +MS P+ +QI+++M  I G  G S+G +R++QLA NTTYFR  L  MG I++GN +SPVIP+++Y   K+ AF RE +++ IG V+VG+PA +L  +R RFCISAAH+K  LD   S
Sbjct:   70 FTESFEETPMLVAVLTNVGYVILIIFGYLRDLLRHWKIEQRHIAREKEEQKDFVPLYRDFQNFYTRNLYMRIRDNWNRPICSVPGAKMDLMDRTSHDYNWTFEYNGRTMKDVINLGSYNYLGFAENTGPCADSAAQVVRTYGIGVASTRQEIGNLDKHEEMEKQVAKFLGVESAMAFGMGFATNSMNIPALVGKGCLILSDELNHTSLVLGARLSGATIRVFKHNNMQCLEKLLSEAIIYGQPRTHRPWKKILIVVEGIYSMEGSIVRLPEVITLKKRYKAYLYLDEAHSIGALGHRGRGVVDYFDLDPRDVDVLMGTFTKSFGAAGGYIAGKRELIEYLRSHSHSAVYAASMSPPVVEQIITSMKCIMGDDGTSIGCKRLQQLAENTTYFRRRLREMGFIIYGNDDSPVIPMMLYMPAKIGAFGREMLKKNIGVVVVGFPATSLVESRARFCISAAHSKEILDTLFS 537
[Close]
BLAST of Serine palmitoyltransferase 2 vs. Planmine SMEST
Match: SMESG000016646.1 (SMESG000016646.1)

HSP 1 Score: 1128.62 bits (2918), Expect = 0.000e+0
Identity = 543/546 (99.45%), Postives = 545/546 (99.82%), Query Frame = 1 
Query:   25 MNPSNGHIKSIKQETKCKESEFFEQFEKASLFNSLITYLYFFILKCMGKLRDFMRNYGLEKNRLAVDSTKNKGFAPLYLDFEAFYTRNVYRRVCDCVNKPICSAPGGSLKAMNRVSDDHNWTFRILDSTSDIYNFGSYNYLGFAQNDGLCTDYVEKSINEFGLSVGSPRQEVGNTLYHLELEESLAEFLGQEAAIVFPMGFATNALNIPILVDKDCCVISDELNHVSLILGIRLSGADTRRFKHNNVESLERELIKAITEGHSKTKRKFKKILVVVEGVYSMEGSIVRLPEILELKKKYKFYIYLDEAHSIGALGKGGRGVVDYFNLNPHEVDIQMGTFTKSFASSGGYISGSRNLIHYVREKSHSTIYGGTMSGPICQQILSAMAIIGGKMGGSLGAERIRQLAWNTTYFRAALHRMGLIVFGNKNSPVIPVIVYTIPKVVAFHRECMRRGIGTVIVGYPACNLKLARIRFCISAAHTKRSLDYTLSIVDEIATHLRFKYSRLPVPDWCKNVPQRSLIFNENKCCDKYDSCKISISNGKFTAPFA 1662
            MNPSNGHIKS KQETKCKESEFFEQFEKASLFNSLITYLYFFILKCMGKLRDFMRNYGLEKNRLAVDSTKNKGFAPLYLDFEAFYTRNVYRRVCDCVNKPICSAPGGSLKAMNRVSDDHNWTFRILDSTSDIYNFGSYNYLGFAQNDGLCTD+VEKSINEFGLSVGSPRQEVGNTLYHLELEESLAEFLGQEAAIVFPMGFATNALNIPILVDKDCCVISDELNHVSLILGIRLSGADTRRFKHNNVESLERELIKAITEGHSKTKRKFKKILVVVEGVYSMEGSIVRLPEILELKKKYKFYIYLDEAHSIGALGKGGRGVVDYFN+NPHEVDIQMGTFTKSFASSGGYISGSRNLIHYVREKSHSTIYGGTMSGPICQQILSAMAIIGGKMGGSLGAERIRQLAWNTTYFRAALHRMGLIVFGNKNSPVIPVIVYTIPKVVAFHRECMRRGIGTVIVGYPACNLKLARIRFCISAAHTKRSLDYTLSIVDEIATHLRFKYSRLPVPDWCKNVPQRSLIFNENKCCDKYDSCKISISNGKFTAPFA
Sbjct:    1 MNPSNGHIKSFKQETKCKESEFFEQFEKASLFNSLITYLYFFILKCMGKLRDFMRNYGLEKNRLAVDSTKNKGFAPLYLDFEAFYTRNVYRRVCDCVNKPICSAPGGSLKAMNRVSDDHNWTFRILDSTSDIYNFGSYNYLGFAQNDGLCTDHVEKSINEFGLSVGSPRQEVGNTLYHLELEESLAEFLGQEAAIVFPMGFATNALNIPILVDKDCCVISDELNHVSLILGIRLSGADTRRFKHNNVESLERELIKAITEGHSKTKRKFKKILVVVEGVYSMEGSIVRLPEILELKKKYKFYIYLDEAHSIGALGKGGRGVVDYFNVNPHEVDIQMGTFTKSFASSGGYISGSRNLIHYVREKSHSTIYGGTMSGPICQQILSAMAIIGGKMGGSLGAERIRQLAWNTTYFRAALHRMGLIVFGNKNSPVIPVIVYTIPKVVAFHRECMRRGIGTVIVGYPACNLKLARIRFCISAAHTKRSLDYTLSIVDEIATHLRFKYSRLPVPDWCKNVPQRSLIFNENKCCDKYDSCKISISNGKFTAPFA 546
[Close]
BLAST of Serine palmitoyltransferase 2 vs. Planmine SMEST
Match: SMESG000016646.1 (SMESG000016646.1)

HSP 1 Score: 1035.02 bits (2675), Expect = 0.000e+0
Identity = 498/500 (99.60%), Postives = 500/500 (100.00%), Query Frame = 1 
Query:  163 MGKLRDFMRNYGLEKNRLAVDSTKNKGFAPLYLDFEAFYTRNVYRRVCDCVNKPICSAPGGSLKAMNRVSDDHNWTFRILDSTSDIYNFGSYNYLGFAQNDGLCTDYVEKSINEFGLSVGSPRQEVGNTLYHLELEESLAEFLGQEAAIVFPMGFATNALNIPILVDKDCCVISDELNHVSLILGIRLSGADTRRFKHNNVESLERELIKAITEGHSKTKRKFKKILVVVEGVYSMEGSIVRLPEILELKKKYKFYIYLDEAHSIGALGKGGRGVVDYFNLNPHEVDIQMGTFTKSFASSGGYISGSRNLIHYVREKSHSTIYGGTMSGPICQQILSAMAIIGGKMGGSLGAERIRQLAWNTTYFRAALHRMGLIVFGNKNSPVIPVIVYTIPKVVAFHRECMRRGIGTVIVGYPACNLKLARIRFCISAAHTKRSLDYTLSIVDEIATHLRFKYSRLPVPDWCKNVPQRSLIFNENKCCDKYDSCKISISNGKFTAPFA 1662
            MGKLRDFMRNYGLEKNRLAVDSTKNKGFAPLYLDFEAFYTRNVYRRVCDCVNKPICSAPGGSLKAMNRVSDDHNWTFRILDSTSDIYNFGSYNYLGFAQNDGLCTD+VEKSINEFGLSVGSPRQEVGNTLYHLELEESLAEFLGQEAAIVFPMGFATNALNIPILVDKDCCVISDELNHVSLILGIRLSGADTRRFKHNNVESLERELIKAITEGHSKTKRKFKKILVVVEGVYSMEGSIVRLPEILELKKKYKFYIYLDEAHSIGALGKGGRGVVDYFN+NPHEVDIQMGTFTKSFASSGGYISGSRNLIHYVREKSHSTIYGGTMSGPICQQILSAMAIIGGKMGGSLGAERIRQLAWNTTYFRAALHRMGLIVFGNKNSPVIPVIVYTIPKVVAFHRECMRRGIGTVIVGYPACNLKLARIRFCISAAHTKRSLDYTLSIVDEIATHLRFKYSRLPVPDWCKNVPQRSLIFNENKCCDKYDSCKISISNGKFTAPFA
Sbjct:    1 MGKLRDFMRNYGLEKNRLAVDSTKNKGFAPLYLDFEAFYTRNVYRRVCDCVNKPICSAPGGSLKAMNRVSDDHNWTFRILDSTSDIYNFGSYNYLGFAQNDGLCTDHVEKSINEFGLSVGSPRQEVGNTLYHLELEESLAEFLGQEAAIVFPMGFATNALNIPILVDKDCCVISDELNHVSLILGIRLSGADTRRFKHNNVESLERELIKAITEGHSKTKRKFKKILVVVEGVYSMEGSIVRLPEILELKKKYKFYIYLDEAHSIGALGKGGRGVVDYFNVNPHEVDIQMGTFTKSFASSGGYISGSRNLIHYVREKSHSTIYGGTMSGPICQQILSAMAIIGGKMGGSLGAERIRQLAWNTTYFRAALHRMGLIVFGNKNSPVIPVIVYTIPKVVAFHRECMRRGIGTVIVGYPACNLKLARIRFCISAAHTKRSLDYTLSIVDEIATHLRFKYSRLPVPDWCKNVPQRSLIFNENKCCDKYDSCKISISNGKFTAPFA 500
[Close]
BLAST of Serine palmitoyltransferase 2 vs. Planmine SMEST
Match: SMESG000011189.1 (SMESG000011189.1)

HSP 1 Score: 678.322 bits (1749), Expect = 0.000e+0
Identity = 308/501 (61.48%), Postives = 392/501 (78.24%), Query Frame = 1 
Query:   70 KCKESEFFEQFEKASLFNSLITYLYFFILKCMGKLRDFMRNYGLEKNRLAVDSTKNKGFAPLYLDFEAFYTRNVYRRVCDCVNKPICSAPGGSLKAMNRVSDDHNWTFRILDSTSDIYNFGSYNYLGFAQNDGLCTDYVEKSINEFGLSVGSPRQEVGNTLYHLELEESLAEFLGQEAAIVFPMGFATNALNIPILVDKDCCVISDELNHVSLILGIRLSGADTRRFKHNNVESLERELIKAITEGHSKTKRKFKKILVVVEGVYSMEGSIVRLPEILELKKKYKFYIYLDEAHSIGALGKGGRGVVDYFNLNPHEVDIQMGTFTKSFASSGGYISGSRNLIHYVREKSHSTIYGGTMSGPICQQILSAMAIIGGKMGGSLGAERIRQLAWNTTYFRAALHRMGLIVFGNKNSPVIPVIVYTIPKVVAFHRECMRRGIGTVIVGYPACNLKLARIRFCISAAHTKRSLDYTLSIVDEIATHLRFKYSRLPVPDWCKNVPQR 1572
            K  E  FFEQFE A   +++ITY  + +L  +G++RDF+R +  EKN  A    K   F PLY D+EAFYTRN+YRR+ DC N+PICS PG +++ ++R+S+D+NWTF+ L +TS + NFGSYNYLGFAQN G C D VE SI+++GL VGSPRQE GN   H ELE  +A F GQE+AIVFPMGFATN+LN+PILV+K CCVISDELNH SLILGIRLSGA  RRFKHN++ +LE+++ KA+  GH +T+R FKKILVVVEG+YSMEGSIV LP+I+ELKKKY F+IYLDEAHSIGALG  G+GV+DYFN+NP ++D+ MGTFTKSF SSGGYI+G + LI +VRE SHS+IYG  M    CQQI+++M+II GK  G+ G ++I+QL WN  YFRAALH+ G IVFGNK+SPV+P+I+ T  K+ AF REC+ RGIGTV+VG+PA  + LAR RFC+SA+HTK  +D TL ++DE++  +   YSRLPVPDWC N+P +
Sbjct:   15 KTNEHIFFEQFEDAPYLHAVITYCCYIVLNLIGRMRDFLRRWNFEKNYAATAPLKTSSFVPLYQDYEAFYTRNLYRRIRDCWNRPICSVPGATMQLVDRISEDNNWTFKHLKTTSKVINFGSYNYLGFAQNTGACADAVENSISKYGLGVGSPRQECGNHTSHTELERLVATFTGQESAIVFPMGFATNSLNLPILVNKQCCVISDELNHTSLILGIRLSGAHIRRFKHNDMSNLEKQIRKAVIFGHPRTRRPFKKILVVVEGIYSMEGSIVHLPQIVELKKKYNFFIYLDEAHSIGALGPHGKGVIDYFNINPKDIDVAMGTFTKSFGSSGGYIAGDKRLIEFVRENSHSSIYGAPMPAVCCQQIITSMSIIEGKQCGNEGIKKIKQLEWNVHYFRAALHKKGFIVFGNKDSPVVPLIICTPTKLAAFSRECLSRGIGTVVVGFPATTIILARARFCVSASHTKEMIDQTLKVIDEVSALININYSRLPVPDWCNNLPDQ 515
[Close]
BLAST of Serine palmitoyltransferase 2 vs. Planmine SMEST
Match: SMESG000052979.1 (SMESG000052979.1)

HSP 1 Score: 173.711 bits (439), Expect = 7.417e-48
Identity = 117/397 (29.47%), Postives = 202/397 (50.88%), Query Frame = 1 
Query:  340 GGSLKAMNRVSDDHNWTFRILDSTSDIYNFGSYNYLGFAQNDGLCTDYVEKSINEF---GLSVGSPRQEVGNTLYHLELEESLAEFLGQEAAIVFPMGFATNALNIPILVDKDCCVISDELNHVSLILGIRLSGADTRRFKHNNVESLERELIKAITEGHSKTKRKFKKILVVVEGVYSMEGSIVRLPEILELKKKYKFYIYLDEAHSIGALGKGGRGVVDYFNLNPHEVDIQMGTFTKS-FASSGGYISGSRNLIHYVREKSHSTIYGGTMSGPICQQILSAMAIIGGKMGGSLGAERIRQLAWNTTYFRAALHRMGLIVFGNKNSPVIPVIVYTIPKVVAFHRECMRRGIGTVIVGYPACNLKLARIRFCISAAHTKRSLDYTLSIVDEIATHLR 1518
             G  K+   ++     + R+ +   +I NF + NYLG + +  +    +E SI+     G  + S R   G T  H+ LEE LA+F  +EA+I++   F  NA     L+ +D  +ISDELNH S+I GIRL  A   R+K+ ++  L+R L +A         + ++  ++V +GV+SM+G +  L +I+ L ++Y    ++DE H+ G +G  GRG  +++NL    VDI   T  K+   + GGY +GS+ ++  +R+KS   ++  T+   +    + A+ +I     G L      ++  NT  FR  +  +G  + G+   P+ PV++        F  + + +GI  +   YP      ARIR  ISA HT++ +D  +    +I + L+
Sbjct:   46 AGMWKSERVITSKQGPSIRVENLNDEILNFCANNYLGLSGHPKI----IEASISALKSHGAGLSSVRFICGTTDLHVNLEEKLAKFHNREASILYASCFDANAGIFEALLSQDDAIISDELNHASIIDGIRLCKAKKWRYKNGDINDLKRCLEEA---------KSYRLKMIVTDGVFSMDGKMAPLSDIISLSREYDCLTFIDECHATGFIGSTGRGSEEFWNLPVPCVDIINSTLGKAMGGTMGGYTTGSKRIVDMLRQKSRPYLFSNTLPPSVVAASIQALDLIMDDQDGLLD-----KIKANTQRFRTEMTNLGFNISGDSCHPICPVMLGDARLASQFAEKMLTKGIYVIGFSYPVVPKDKARIRVQISAVHTRQQIDKAILAFKQIGSDLK 424
[Close]
BLAST of Serine palmitoyltransferase 2 vs. Planmine SMEST
Match: SMESG000080769.1 (SMESG000080769.1)

HSP 1 Score: 131.724 bits (330), Expect = 6.544e-33
Identity = 79/277 (28.52%), Postives = 143/277 (51.62%), Query Frame = 1 
Query:  403 DSTSDIYNFGSYNYLGFAQNDGLCTDYVEKSINEFGLSVGSPRQEVGNTLYHLELEESLAEFLGQEAAIVFPMGFATNALNIPILVDKDCCVISDELNHVSLILGIRLSGADTRRFKHNNVESLERELIKAITEG-HSKTKRKFKKILVVVEGVYSMEGSIVRLPEILELKKKYKFYIYLDEAHSIGALGKGGRGVVDYFNLNPHEVDIQMGTFTKSFASSGGYISGSRNLIHYVREKSHSTIYGGTMSGPICQQILSAMAIIGGKMGGSLGAERIR 1230
            + T  + N  S+N+     N+ +  +  +K++ ++G+    PR   G    HL+LE+ +A F+  E ++V+  GF+T A  IP    +   + +DE    ++  G+  S +  + FKHN+++ L   L +   E   +  K +  +  +V+EG+Y   G I  LP+I+ELK KYK  I+LDE  S G LG  GRGV D+F ++  ++D+  G+   + A+ GG+  GS+ ++ + R       +  ++   +       + +I  + G    A+RIR
Sbjct:  101 NKTKPVLNLASFNFFNLIGNEKI-NETAQKALRKYGVGSCGPRGFYGTFDVHLKLEDEIANFMNCEESVVYSYGFSTVASAIPAYAKRGDVIFADEGVSFAIQCGLLASRSKIKYFKHNDMDHLVSLLEEQSEEAIKNPAKARITRTFIVIEGLYMNYGDICPLPKIVELKYKYKVRIFLDETLSFGVLGDHGRGVTDHFGVDVTDIDLITGSLETALATCGGFSVGSKYVVDHQRLSGQGYCFSASLPPLLACGASVVLEMIRAEEG---VAQRIR 373
The following BLAST results are available for this feature:
BLAST of Serine palmitoyltransferase 2 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
SPTLC20.000e+052.30serine palmitoyltransferase long chain base subuni... [more]
SPTLC30.000e+051.59serine palmitoyltransferase long chain base subuni... [more]
SPTLC22.161e-14054.18serine palmitoyltransferase long chain base subuni... [more]
GCAT4.872e-4029.30glycine C-acetyltransferase [Source:HGNC Symbol;Ac... [more]
GCAT1.141e-3928.02glycine C-acetyltransferase [Source:HGNC Symbol;Ac... [more]
back to top
BLAST of Serine palmitoyltransferase 2 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
sptl-21.805e-16048.75Serine palmitoyltransferase 2 [Source:UniProtKB/S... [more]
sptl-23.642e-16048.75Serine palmitoyltransferase 2 [Source:UniProtKB/S... [more]
sptl-31.995e-14746.58Serine palmitoyltransferase 3 [Source:UniProtKB/S... [more]
sptl-31.995e-14746.58Serine palmitoyltransferase 3 [Source:UniProtKB/S... [more]
sptl-32.062e-14746.58Serine palmitoyltransferase 3 [Source:UniProtKB/S... [more]
back to top
BLAST of Serine palmitoyltransferase 2 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
lace1.685e-16448.44gene:FBgn0002524 transcript:FBtr0343735[more]
lace1.685e-16448.44gene:FBgn0002524 transcript:FBtr0080738[more]
CG103615.686e-5431.22gene:FBgn0036208 transcript:FBtr0076084[more]
Spt-I7.623e-4030.59gene:FBgn0086532 transcript:FBtr0087731[more]
Spt-I7.623e-4030.59gene:FBgn0086532 transcript:FBtr0087729[more]
back to top
BLAST of Serine palmitoyltransferase 2 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
sptlc2b0.000e+055.07serine palmitoyltransferase, long chain base subun... [more]
sptlc2a0.000e+052.47serine palmitoyltransferase, long chain base subun... [more]
sptlc30.000e+052.78serine palmitoyltransferase, long chain base subun... [more]
sptlc30.000e+052.78serine palmitoyltransferase, long chain base subun... [more]
sptlc2a6.992e-4044.94serine palmitoyltransferase, long chain base subun... [more]
back to top
BLAST of Serine palmitoyltransferase 2 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
wdr930.000e+055.07WD repeat domain 93 [Source:Xenbase;Acc:XB-GENE-64... [more]
wdr930.000e+055.07WD repeat domain 93 [Source:Xenbase;Acc:XB-GENE-64... [more]
wdr930.000e+055.07WD repeat domain 93 [Source:Xenbase;Acc:XB-GENE-64... [more]
wdr930.000e+055.07WD repeat domain 93 [Source:Xenbase;Acc:XB-GENE-64... [more]
wdr930.000e+055.07WD repeat domain 93 [Source:Xenbase;Acc:XB-GENE-64... [more]
back to top
BLAST of Serine palmitoyltransferase 2 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Sptlc20.000e+052.30serine palmitoyltransferase, long chain base subun... [more]
Sptlc31.263e-16248.60serine palmitoyltransferase, long chain base subun... [more]
Sptlc31.263e-16248.60serine palmitoyltransferase, long chain base subun... [more]
Gcat2.044e-4027.84glycine C-acetyltransferase (2-amino-3-ketobutyrat... [more]
Gcat2.101e-3428.48glycine C-acetyltransferase (2-amino-3-ketobutyrat... [more]
back to top
BLAST of Serine palmitoyltransferase 2 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|P97363|SPTC2_MOUSE0.000e+052.30Serine palmitoyltransferase 2 OS=Mus musculus OX=1... [more]
sp|Q3B7D2|SPTC2_RAT0.000e+052.18Serine palmitoyltransferase 2 OS=Rattus norvegicus... [more]
sp|O15270|SPTC2_HUMAN0.000e+052.30Serine palmitoyltransferase 2 OS=Homo sapiens OX=9... [more]
sp|O54694|SPTC2_CRIGR0.000e+051.90Serine palmitoyltransferase 2 OS=Cricetulus griseu... [more]
sp|Q9NUV7|SPTC3_HUMAN0.000e+051.59Serine palmitoyltransferase 3 OS=Homo sapiens OX=9... [more]
back to top
BLAST of Serine palmitoyltransferase 2 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A068XW600.000e+055.75Serine palmitoyltransferase long chain base OS=Ech... [more]
A0A4Z2DW010.000e+055.89Serine palmitoyltransferase 2 OS=Schistosoma japon... [more]
A0A068X1160.000e+057.55Serine palmitoyltransferase long chain base OS=Ech... [more]
A0A564Y7560.000e+056.66Aminotran_1_2 domain-containing protein OS=Hymenol... [more]
A0A0X3PSW20.000e+056.37Serine palmitoyltransferase 2 (Fragment) OS=Schist... [more]
back to top
BLAST of Serine palmitoyltransferase 2 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
sptlc2a0.000e+052.14serine palmitoyltransferase, long chain base subun... [more]
sptlc2a0.000e+052.14serine palmitoyltransferase, long chain base subun... [more]
sptlc2a0.000e+052.14serine palmitoyltransferase, long chain base subun... [more]
gcat5.628e-3928.46glycine C-acetyltransferase [Source:NCBI gene;Acc:... [more]
sptlc17.971e-3732.09serine palmitoyltransferase, long chain base subun... [more]
back to top
BLAST of Serine palmitoyltransferase 2 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 3
Match NameE-valueIdentityDescription
sptlc2a0.000e+054.77serine palmitoyltransferase, long chain base subun... [more]
alas22.815e-3130.59aminolevulinate, delta-, synthase 2 [Source:NCBI g... [more]
sptlc11.094e-2729.88serine palmitoyltransferase, long chain base subun... [more]
back to top
BLAST of Serine palmitoyltransferase 2 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 3
Match NameE-valueIdentityDescription
LCB27.446e-13741.25Component of serine palmitoyltransferase; responsi... [more]
HEM19.271e-3626.395-aminolevulinate synthase; catalyzes the first st... [more]
LCB12.321e-2827.38Component of serine palmitoyltransferase; responsi... [more]
back to top
BLAST of Serine palmitoyltransferase 2 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO429900.000e+052.30Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO272201.627e-5130.89Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO384901.061e-4232.02Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO462061.386e-2824.285-aminolevulinate synthase [Source:UniProtKB/TrEM... [more]
EDO360821.446e-2830.23Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
back to top
BLAST of Serine palmitoyltransferase 2 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ENSORLT00000022091.20.000e+051.35serine palmitoyltransferase 2-like [Source:NCBI ge... [more]
ENSORLT00000042858.10.000e+052.16serine palmitoyltransferase 2-like [Source:NCBI ge... [more]
sptlc2b0.000e+052.74serine palmitoyltransferase 2 [Source:NCBI gene;Ac... [more]
sptlc30.000e+053.66serine palmitoyltransferase long chain base subuni... [more]
ENSORLT00000013273.20.000e+053.63serine palmitoyltransferase 2-like [Source:NCBI ge... [more]
back to top
BLAST of Serine palmitoyltransferase 2 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000016646.10.000e+099.45SMESG000016646.1[more]
SMESG000016646.10.000e+099.60SMESG000016646.1[more]
SMESG000011189.10.000e+061.48SMESG000011189.1[more]
SMESG000052979.17.417e-4829.47SMESG000052979.1[more]
SMESG000080769.16.544e-3328.52SMESG000080769.1[more]
back to top
Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30028172 ID=SMED30028172|Name=Serine palmitoyltransferase 2|organism=Schmidtea mediterranea sexual|type=transcript|length=1844bp
ATCTATATAAATCTTATATGACAAATGAATCCATCTAACGGTCATATAAA
ATCAATTAAACAAGAAACAAAGTGTAAGGAATCTGAGTTTTTCGAACAAT
TTGAGAAGGCTTCTCTTTTCAATTCTCTGATAACATATCTATATTTCTTC
ATCCTGAAATGTATGGGGAAACTAAGAGATTTTATGAGAAATTATGGATT
AGAAAAAAATCGGCTTGCTGTGGATTCTACAAAAAACAAAGGTTTCGCAC
CGTTATATTTGGATTTTGAGGCTTTCTATACGAGAAATGTTTACAGACGG
GTCTGTGATTGTGTGAATAAACCGATTTGTAGTGCTCCAGGAGGCTCATT
AAAAGCAATGAATCGAGTATCAGATGATCATAATTGGACATTTAGAATCC
TAGATTCTACAAGTGATATCTACAATTTCGGATCTTACAACTATTTGGGG
TTTGCGCAAAATGATGGACTTTGTACTGATTACGTTGAAAAATCAATAAA
TGAATTCGGACTTTCAGTTGGTTCACCAAGACAAGAAGTAGGAAATACTC
TCTATCATTTAGAACTAGAAGAATCTTTGGCTGAATTTTTAGGTCAAGAA
GCAGCCATAGTGTTTCCGATGGGATTCGCTACAAATGCTCTTAATATTCC
AATTTTGGTAGATAAAGATTGTTGTGTTATTAGCGATGAGCTTAATCATG
TCAGTTTAATATTGGGTATCAGACTTTCAGGAGCAGATACGAGACGATTT
AAACATAATAATGTCGAATCTTTAGAAAGAGAATTAATTAAAGCCATAAC
TGAGGGTCATTCGAAAACGAAACGAAAATTCAAAAAAATCCTCGTCGTCG
TTGAAGGAGTTTACAGCATGGAAGGAAGCATTGTACGATTGCCTGAAATT
TTGGAGCTGAAGAAAAAGTACAAATTCTACATCTATTTAGATGAAGCTCA
CAGTATCGGTGCTCTCGGAAAAGGTGGTCGTGGGGTTGTAGACTACTTCA
ATCTTAATCCACATGAAGTGGACATCCAAATGGGAACATTTACGAAAAGT
TTCGCATCCTCTGGTGGATACATTAGTGGTTCCCGTAACTTAATACATTA
TGTAAGAGAAAAATCTCACAGCACAATTTATGGTGGCACAATGTCTGGAC
CGATTTGTCAGCAAATTCTTTCTGCTATGGCTATAATTGGAGGTAAAATG
GGGGGCAGTTTGGGCGCAGAAAGAATTCGTCAACTTGCTTGGAATACGAC
TTATTTCCGAGCAGCTCTTCACCGAATGGGTCTCATAGTTTTTGGCAATA
AGAACAGTCCTGTGATTCCCGTTATAGTATATACTATTCCGAAAGTTGTA
GCCTTTCATAGGGAATGCATGCGGCGAGGAATTGGAACGGTTATTGTGGG
TTATCCAGCCTGCAATTTGAAGCTTGCAAGAATCAGATTTTGTATTAGTG
CTGCTCACACAAAACGCTCATTAGATTACACTCTTTCAATTGTTGATGAA
ATCGCAACTCATTTAAGATTCAAGTACAGCAGGTTGCCGGTACCAGATTG
GTGTAAGAATGTTCCTCAGCGCTCATTAATTTTTAATGAAAATAAATGCT
GTGATAAATATGATTCGTGCAAAATTTCCATATCTAATGGGAAATTCACC
GCGCCTTTTGCTTGATATTTAATTTTTAAACGTTTATTTTTTTAACAAAA
AAATGAAATATATGGATAAGTTTTATGATTATAATAATTGAAAAATCATC
TCAATTAGTTTTGTATCATTTTATATGTAGGGATTTTGAGTTACTTTTAA
TTTGGTAATTGTTTACCGAGGATTTTGAGAATATTCTAAATTGT
back to top

protein sequence of SMED30028172-orf-1

>SMED30028172-orf-1 ID=SMED30028172-orf-1|Name=SMED30028172-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=547bp
MNPSNGHIKSIKQETKCKESEFFEQFEKASLFNSLITYLYFFILKCMGKL
RDFMRNYGLEKNRLAVDSTKNKGFAPLYLDFEAFYTRNVYRRVCDCVNKP
ICSAPGGSLKAMNRVSDDHNWTFRILDSTSDIYNFGSYNYLGFAQNDGLC
TDYVEKSINEFGLSVGSPRQEVGNTLYHLELEESLAEFLGQEAAIVFPMG
FATNALNIPILVDKDCCVISDELNHVSLILGIRLSGADTRRFKHNNVESL
ERELIKAITEGHSKTKRKFKKILVVVEGVYSMEGSIVRLPEILELKKKYK
FYIYLDEAHSIGALGKGGRGVVDYFNLNPHEVDIQMGTFTKSFASSGGYI
SGSRNLIHYVREKSHSTIYGGTMSGPICQQILSAMAIIGGKMGGSLGAER
IRQLAWNTTYFRAALHRMGLIVFGNKNSPVIPVIVYTIPKVVAFHRECMR
RGIGTVIVGYPACNLKLARIRFCISAAHTKRSLDYTLSIVDEIATHLRFK
YSRLPVPDWCKNVPQRSLIFNENKCCDKYDSCKISISNGKFTAPFA*
back to top
Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: cellular component
TermDefinition
GO:0016020membrane
GO:0016021integral component of membrane
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000016pharynx
PLANA:0000026gut
PLANA:0000034epidermis
PLANA:0000070intestinal phagocyte
PLANA:0000099neuron
PLANA:0002032epidermal cell
Vocabulary: INTERPRO
TermDefinition
IPR004839Aminotransferase_I/II
IPR015421PyrdxlP-dep_Trfase_major
IPR015422PyrdxlP-dep_Trfase_dom1
IPR001917Aminotrans_II_pyridoxalP_BS
IPR015424PyrdxlP-dep_Trfase
Vocabulary: molecular function
TermDefinition
GO:0030170pyridoxal phosphate binding
GO:0003824catalytic activity
GO:0016740transferase activity
Vocabulary: biological process
TermDefinition
GO:0009058biosynthetic process
GO:0008152metabolic process