menin

Overview
Namemenin (AGA95403.1)
Smed IDSMED30028101
Length (bp)2711
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of menin (SMED30028101) t-SNE clustered cells

Violin plots show distribution of expression levels for menin (SMED30028101) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of menin (SMED30028101) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for menin (SMED30028101) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30028101

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 4

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
cephalic gangliaSMED30028101h1SMcG0018292 KC262339smed_ncbi_20240424PMID:23235145
Hubert et al., 2013		whole organism asexual adult colorimetric in situ hybridization evidence
ventral nerve cordSMED30028101h1SMcG0018292 KC262339smed_ncbi_20240424PMID:23235145
Hubert et al., 2013		whole organism asexual adult colorimetric in situ hybridization evidence
neoblastSMED30028101h1SMcG0018292 KC262339smed_ncbi_20240424PMID:23235145
Hubert et al., 2013		whole organism asexual adult colorimetric in situ hybridization evidence
parenchymal cellSMED30028101h1SMcG0018292 KC262339smed_ncbi_20240424PMID:23235145
Hubert et al., 2013		whole organism asexual adult colorimetric in situ hybridization evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of menin vs. Ensembl Human
Match: MEN1 (menin 1 [Source:HGNC Symbol;Acc:HGNC:7010])

HSP 1 Score: 228.024 bits (580), Expect = 8.278e-64
Identity = 158/513 (30.80%), Postives = 247/513 (48.15%), Query Frame = 2 
Query:   95 KKYFPLTNINDILTLFESLLSMSKLENSYEPNIAFVSILLGVIEYKLTHNADDDENQCENVFINNIDDYASVKILYITFND---VIVLYKKFQSILWEMINCK-SPKSEDVNKFLDRCTLKHITDAVYQKLSVGKYKENCHSQSIYSFIQDNSLDSFGLSYTILAITQQLGYKNIWLSLSEDHAWLEYEGNDINNNQSASSNSHKITADVAWSGKNHENKRCGSIDIGIIERSRLYLGGNSVVCSNNRITVAAAITTINPVKGSHSLSLNGYSNRNQIITSCHSSELAYLKRDLLWIAYKMNLLEKYPLALINLADLEMNYPKNTLNPNGNYFFGLLGLYREAADINLKYYNNSHVYPYLSMANYFYKDGDYQRALTCWRLAANVISKYNYKSEDWIIYREFFEIATHFVPNIFRLNNKEDDHHSKSSGSVYHASENESTKDRNRVSVDCKSLTCDELKNSVEFLSEFLCFFDFICLWEEGSSVPVLHEVWANKFKEVLCRFSESTRVELNTI 1621
            K  FPL +I+D++ LF + L         EP++  +S++LG +E+ L  N     N  E  F  +        + Y    D   +  LY +F + +   ++    P+   V+    R  +K ++D ++  LS   +K+  H QS++SFI    LDS G+++ ++   Q LG +++ L+LSEDHAW+ +  N             + TA+V W GK +E++R  +++ G+ ERS LYL G+ + C + ++ VA  +  INP     S+ L+             S EL  L++ LLW+ Y +  LE+YP+AL NLADLE   P     P+       L LY +       YY + H+YPY+ +A Y  ++ + + AL  W   A VI  YNY  ED  IY+EFFE+A   +PN+            K + S+  A E    +          +L         E  +  L F+D IC WEEGS  PVLH  WA    + L RF    R ++  +
Sbjct:    8 KTLFPLRSIDDVVRLFAAELGRE------EPDLVLLSLVLGFVEHFLAVNRVIPTNVPELTFQPSPAPDPPGGLTYFPVADLSIIAALYARFTAQIRGAVDLSLYPREGGVS---SRELVKKVSDVIWNSLSRSYFKDRAHIQSLFSFITGTKLDSSGVAFAVVGACQALGLRDVHLALSEDHAWVVFGPNG------------EQTAEVTWHGKGNEDRRGQTVNAGVAERSWLYLKGSYMRC-DRKMEVAFMVCAINP-----SIDLH-----------TDSLELLQLQQKLLWLLYDLGHLERYPMALGNLADLEELEPTPG-RPD------PLTLYHKGIASAKTYYRDEHIYPYMYLAGYHCRNRNVREALQAWADTATVIQDYNYCREDEEIYKEFFEVANDVIPNLL-----------KEAASLLEAGEERPGEQSQGTQSQGSAL------QDPECFAHLLRFYDGICKWEEGSPTPVLHVGWATFLVQSLGRFEGQVRQKVRIV 458
[Close]
BLAST of menin vs. Ensembl Human
Match: MEN1 (menin 1 [Source:HGNC Symbol;Acc:HGNC:7010])

HSP 1 Score: 228.024 bits (580), Expect = 8.278e-64
Identity = 158/513 (30.80%), Postives = 247/513 (48.15%), Query Frame = 2 
Query:   95 KKYFPLTNINDILTLFESLLSMSKLENSYEPNIAFVSILLGVIEYKLTHNADDDENQCENVFINNIDDYASVKILYITFND---VIVLYKKFQSILWEMINCK-SPKSEDVNKFLDRCTLKHITDAVYQKLSVGKYKENCHSQSIYSFIQDNSLDSFGLSYTILAITQQLGYKNIWLSLSEDHAWLEYEGNDINNNQSASSNSHKITADVAWSGKNHENKRCGSIDIGIIERSRLYLGGNSVVCSNNRITVAAAITTINPVKGSHSLSLNGYSNRNQIITSCHSSELAYLKRDLLWIAYKMNLLEKYPLALINLADLEMNYPKNTLNPNGNYFFGLLGLYREAADINLKYYNNSHVYPYLSMANYFYKDGDYQRALTCWRLAANVISKYNYKSEDWIIYREFFEIATHFVPNIFRLNNKEDDHHSKSSGSVYHASENESTKDRNRVSVDCKSLTCDELKNSVEFLSEFLCFFDFICLWEEGSSVPVLHEVWANKFKEVLCRFSESTRVELNTI 1621
            K  FPL +I+D++ LF + L         EP++  +S++LG +E+ L  N     N  E  F  +        + Y    D   +  LY +F + +   ++    P+   V+    R  +K ++D ++  LS   +K+  H QS++SFI    LDS G+++ ++   Q LG +++ L+LSEDHAW+ +  N             + TA+V W GK +E++R  +++ G+ ERS LYL G+ + C + ++ VA  +  INP     S+ L+             S EL  L++ LLW+ Y +  LE+YP+AL NLADLE   P     P+       L LY +       YY + H+YPY+ +A Y  ++ + + AL  W   A VI  YNY  ED  IY+EFFE+A   +PN+            K + S+  A E    +          +L         E  +  L F+D IC WEEGS  PVLH  WA    + L RF    R ++  +
Sbjct:    8 KTLFPLRSIDDVVRLFAAELGRE------EPDLVLLSLVLGFVEHFLAVNRVIPTNVPELTFQPSPAPDPPGGLTYFPVADLSIIAALYARFTAQIRGAVDLSLYPREGGVS---SRELVKKVSDVIWNSLSRSYFKDRAHIQSLFSFITGTKLDSSGVAFAVVGACQALGLRDVHLALSEDHAWVVFGPNG------------EQTAEVTWHGKGNEDRRGQTVNAGVAERSWLYLKGSYMRC-DRKMEVAFMVCAINP-----SIDLH-----------TDSLELLQLQQKLLWLLYDLGHLERYPMALGNLADLEELEPTPG-RPD------PLTLYHKGIASAKTYYRDEHIYPYMYLAGYHCRNRNVREALQAWADTATVIQDYNYCREDEEIYKEFFEVANDVIPNLL-----------KEAASLLEAGEERPGEQSQGTQSQGSAL------QDPECFAHLLRFYDGICKWEEGSPTPVLHVGWATFLVQSLGRFEGQVRQKVRIV 458
[Close]
BLAST of menin vs. Ensembl Human
Match: MEN1 (menin 1 [Source:HGNC Symbol;Acc:HGNC:7010])

HSP 1 Score: 228.024 bits (580), Expect = 8.278e-64
Identity = 158/513 (30.80%), Postives = 247/513 (48.15%), Query Frame = 2 
Query:   95 KKYFPLTNINDILTLFESLLSMSKLENSYEPNIAFVSILLGVIEYKLTHNADDDENQCENVFINNIDDYASVKILYITFND---VIVLYKKFQSILWEMINCK-SPKSEDVNKFLDRCTLKHITDAVYQKLSVGKYKENCHSQSIYSFIQDNSLDSFGLSYTILAITQQLGYKNIWLSLSEDHAWLEYEGNDINNNQSASSNSHKITADVAWSGKNHENKRCGSIDIGIIERSRLYLGGNSVVCSNNRITVAAAITTINPVKGSHSLSLNGYSNRNQIITSCHSSELAYLKRDLLWIAYKMNLLEKYPLALINLADLEMNYPKNTLNPNGNYFFGLLGLYREAADINLKYYNNSHVYPYLSMANYFYKDGDYQRALTCWRLAANVISKYNYKSEDWIIYREFFEIATHFVPNIFRLNNKEDDHHSKSSGSVYHASENESTKDRNRVSVDCKSLTCDELKNSVEFLSEFLCFFDFICLWEEGSSVPVLHEVWANKFKEVLCRFSESTRVELNTI 1621
            K  FPL +I+D++ LF + L         EP++  +S++LG +E+ L  N     N  E  F  +        + Y    D   +  LY +F + +   ++    P+   V+    R  +K ++D ++  LS   +K+  H QS++SFI    LDS G+++ ++   Q LG +++ L+LSEDHAW+ +  N             + TA+V W GK +E++R  +++ G+ ERS LYL G+ + C + ++ VA  +  INP     S+ L+             S EL  L++ LLW+ Y +  LE+YP+AL NLADLE   P     P+       L LY +       YY + H+YPY+ +A Y  ++ + + AL  W   A VI  YNY  ED  IY+EFFE+A   +PN+            K + S+  A E    +          +L         E  +  L F+D IC WEEGS  PVLH  WA    + L RF    R ++  +
Sbjct:    8 KTLFPLRSIDDVVRLFAAELGRE------EPDLVLLSLVLGFVEHFLAVNRVIPTNVPELTFQPSPAPDPPGGLTYFPVADLSIIAALYARFTAQIRGAVDLSLYPREGGVS---SRELVKKVSDVIWNSLSRSYFKDRAHIQSLFSFITGTKLDSSGVAFAVVGACQALGLRDVHLALSEDHAWVVFGPNG------------EQTAEVTWHGKGNEDRRGQTVNAGVAERSWLYLKGSYMRC-DRKMEVAFMVCAINP-----SIDLH-----------TDSLELLQLQQKLLWLLYDLGHLERYPMALGNLADLEELEPTPG-RPD------PLTLYHKGIASAKTYYRDEHIYPYMYLAGYHCRNRNVREALQAWADTATVIQDYNYCREDEEIYKEFFEVANDVIPNLL-----------KEAASLLEAGEERPGEQSQGTQSQGSAL------QDPECFAHLLRFYDGICKWEEGSPTPVLHVGWATFLVQSLGRFEGQVRQKVRIV 458
[Close]
BLAST of menin vs. Ensembl Human
Match: MEN1 (menin 1 [Source:HGNC Symbol;Acc:HGNC:7010])

HSP 1 Score: 228.024 bits (580), Expect = 8.278e-64
Identity = 158/513 (30.80%), Postives = 247/513 (48.15%), Query Frame = 2 
Query:   95 KKYFPLTNINDILTLFESLLSMSKLENSYEPNIAFVSILLGVIEYKLTHNADDDENQCENVFINNIDDYASVKILYITFND---VIVLYKKFQSILWEMINCK-SPKSEDVNKFLDRCTLKHITDAVYQKLSVGKYKENCHSQSIYSFIQDNSLDSFGLSYTILAITQQLGYKNIWLSLSEDHAWLEYEGNDINNNQSASSNSHKITADVAWSGKNHENKRCGSIDIGIIERSRLYLGGNSVVCSNNRITVAAAITTINPVKGSHSLSLNGYSNRNQIITSCHSSELAYLKRDLLWIAYKMNLLEKYPLALINLADLEMNYPKNTLNPNGNYFFGLLGLYREAADINLKYYNNSHVYPYLSMANYFYKDGDYQRALTCWRLAANVISKYNYKSEDWIIYREFFEIATHFVPNIFRLNNKEDDHHSKSSGSVYHASENESTKDRNRVSVDCKSLTCDELKNSVEFLSEFLCFFDFICLWEEGSSVPVLHEVWANKFKEVLCRFSESTRVELNTI 1621
            K  FPL +I+D++ LF + L         EP++  +S++LG +E+ L  N     N  E  F  +        + Y    D   +  LY +F + +   ++    P+   V+    R  +K ++D ++  LS   +K+  H QS++SFI    LDS G+++ ++   Q LG +++ L+LSEDHAW+ +  N             + TA+V W GK +E++R  +++ G+ ERS LYL G+ + C + ++ VA  +  INP     S+ L+             S EL  L++ LLW+ Y +  LE+YP+AL NLADLE   P     P+       L LY +       YY + H+YPY+ +A Y  ++ + + AL  W   A VI  YNY  ED  IY+EFFE+A   +PN+            K + S+  A E    +          +L         E  +  L F+D IC WEEGS  PVLH  WA    + L RF    R ++  +
Sbjct:    8 KTLFPLRSIDDVVRLFAAELGRE------EPDLVLLSLVLGFVEHFLAVNRVIPTNVPELTFQPSPAPDPPGGLTYFPVADLSIIAALYARFTAQIRGAVDLSLYPREGGVS---SRELVKKVSDVIWNSLSRSYFKDRAHIQSLFSFITGTKLDSSGVAFAVVGACQALGLRDVHLALSEDHAWVVFGPNG------------EQTAEVTWHGKGNEDRRGQTVNAGVAERSWLYLKGSYMRC-DRKMEVAFMVCAINP-----SIDLH-----------TDSLELLQLQQKLLWLLYDLGHLERYPMALGNLADLEELEPTPG-RPD------PLTLYHKGIASAKTYYRDEHIYPYMYLAGYHCRNRNVREALQAWADTATVIQDYNYCREDEEIYKEFFEVANDVIPNLL-----------KEAASLLEAGEERPGEQSQGTQSQGSAL------QDPECFAHLLRFYDGICKWEEGSPTPVLHVGWATFLVQSLGRFEGQVRQKVRIV 458
[Close]
BLAST of menin vs. Ensembl Human
Match: MEN1 (menin 1 [Source:HGNC Symbol;Acc:HGNC:7010])

HSP 1 Score: 228.024 bits (580), Expect = 8.278e-64
Identity = 158/513 (30.80%), Postives = 247/513 (48.15%), Query Frame = 2 
Query:   95 KKYFPLTNINDILTLFESLLSMSKLENSYEPNIAFVSILLGVIEYKLTHNADDDENQCENVFINNIDDYASVKILYITFND---VIVLYKKFQSILWEMINCK-SPKSEDVNKFLDRCTLKHITDAVYQKLSVGKYKENCHSQSIYSFIQDNSLDSFGLSYTILAITQQLGYKNIWLSLSEDHAWLEYEGNDINNNQSASSNSHKITADVAWSGKNHENKRCGSIDIGIIERSRLYLGGNSVVCSNNRITVAAAITTINPVKGSHSLSLNGYSNRNQIITSCHSSELAYLKRDLLWIAYKMNLLEKYPLALINLADLEMNYPKNTLNPNGNYFFGLLGLYREAADINLKYYNNSHVYPYLSMANYFYKDGDYQRALTCWRLAANVISKYNYKSEDWIIYREFFEIATHFVPNIFRLNNKEDDHHSKSSGSVYHASENESTKDRNRVSVDCKSLTCDELKNSVEFLSEFLCFFDFICLWEEGSSVPVLHEVWANKFKEVLCRFSESTRVELNTI 1621
            K  FPL +I+D++ LF + L         EP++  +S++LG +E+ L  N     N  E  F  +        + Y    D   +  LY +F + +   ++    P+   V+    R  +K ++D ++  LS   +K+  H QS++SFI    LDS G+++ ++   Q LG +++ L+LSEDHAW+ +  N             + TA+V W GK +E++R  +++ G+ ERS LYL G+ + C + ++ VA  +  INP     S+ L+             S EL  L++ LLW+ Y +  LE+YP+AL NLADLE   P     P+       L LY +       YY + H+YPY+ +A Y  ++ + + AL  W   A VI  YNY  ED  IY+EFFE+A   +PN+            K + S+  A E    +          +L         E  +  L F+D IC WEEGS  PVLH  WA    + L RF    R ++  +
Sbjct:    8 KTLFPLRSIDDVVRLFAAELGRE------EPDLVLLSLVLGFVEHFLAVNRVIPTNVPELTFQPSPAPDPPGGLTYFPVADLSIIAALYARFTAQIRGAVDLSLYPREGGVS---SRELVKKVSDVIWNSLSRSYFKDRAHIQSLFSFITGTKLDSSGVAFAVVGACQALGLRDVHLALSEDHAWVVFGPNG------------EQTAEVTWHGKGNEDRRGQTVNAGVAERSWLYLKGSYMRC-DRKMEVAFMVCAINP-----SIDLH-----------TDSLELLQLQQKLLWLLYDLGHLERYPMALGNLADLEELEPTPG-RPD------PLTLYHKGIASAKTYYRDEHIYPYMYLAGYHCRNRNVREALQAWADTATVIQDYNYCREDEEIYKEFFEVANDVIPNLL-----------KEAASLLEAGEERPGEQSQGTQSQGSAL------QDPECFAHLLRFYDGICKWEEGSPTPVLHVGWATFLVQSLGRFEGQVRQKVRIV 458
[Close]
BLAST of menin vs. Ensembl Fly
Match: Mnn1 (gene:FBgn0031885 transcript:FBtr0079401)

HSP 1 Score: 195.282 bits (495), Expect = 1.015e-51
Identity = 215/802 (26.81%), Postives = 353/802 (44.01%), Query Frame = 2 
Query:  104 FPLTNINDILTLFESLLSMSKLENSYEPNIAFVSILLGVIEYKLTHN--------------ADDDENQCENVFINNIDDYASVKILYITFNDVIVLYKKFQSILWEMINCKSPKSEDVNKFLDRCTLKHITDAVYQKLSVGKYKENCHSQSIYSFIQDNSLDSFGLSYTILAITQQLGYKNIWLSLSEDHAWLEYEGNDINNNQSASSNSHKITADVAWSGKNHENKRCGSIDIGIIERSRLYLGGNSVVCSNNRITVAAAITTINPVKGSHSLSLNGYSNRNQIITSCHSSELAYLKRDLLWIAYKMNLLEKYPLALINLADLE---MNYPKNTLNPNGNYFFGLLGLYREAADINLKYYNNSHVYPYLSMANYFYKDGDYQRALTCWRLAANVISKYNYK-SEDWIIYREFFEIATHFVPNIFRLNNKEDDHHSKSSGSVYHASENESTKDRNRVSVDCKSLTCDELKNSVEFLSEFLCFFDFICLWEEGSSVPVLHEVWANKFKEVLCRFSESTRVELNTIGVDANILNEIQSIEEILFLPSNCSKPICQPKHDENESKPMSLVKSRQNSPNKSKRKPIKRLSLSNEELNQIKEFWIALCNNETKNLSTILSSKVLNLDFLLNFNSVKMFELSHILEPIDYENLNCE-------NLCQLKTDKEFIDYFSTFKSVRDILNDNNDRNTSSSINSTQKNIESDQVLQELS-NDQSHRCKYENSSNVPKIILESKSENEINQKSSYKIDSKSCQKIPLMDVFKSQKMKDICPLIVAPGKLNVPAIKLPLTAQSQVSLKRTGL 2431
            FPL +  D++ LF   L+     +  EP++  +SI++G IE  LT                A  D +Q      N+I    SV    +T   +  LYKKFQ+IL  +   + PK    ++   R  +K ++D ++  L    YK+  H Q++YS++  N LD FG++  ++A  Q LGYK++ L++SEDHAW+ +    +             T +V W GK  E+KR   I  GI   S LYLGG +VVC    + VAA    +N       +SL   S+       C   E+A L++ LLW+ Y +  L++YP+AL  L +LE     +P  +             LYREA +    +Y N HVYPY    NY+ +   Y+ A   W  AA+VI  Y Y+  +D  IY+E  +IA   +P + +         ++SSG   H++               +S+  D      E  +  L F+D IC WEE S  P+LH  WA      + +F             D +I +++     ++ LP +      + +    E +     +S++ + +++      R++ + EE ++  E    L      +L+     K+LN DFLL        +     +P   E+ N E       +      +    D      +  +    +N   TS  +  + +   + Q   ++  NDQ  + +++          E+K E   +    ++I      K P++ ++ SQKMK +  L++A  KLN  AI L +TAQS  S K  G+
Sbjct:   24 FPLKSTADVINLFRRALT-----SGIEPDLTLLSIVVGYIELSLTTGEAAAQAAQAAAAAVAAGDISQA-TTGGNDIIMGNSVPFPVVTHELIAGLYKKFQTILSVV---EKPKP---HRQATREVIKKVSDVIWNSLIRSSYKDRAHLQNLYSYLSGNKLDCFGVALAVVAGCQLLGYKDVRLAISEDHAWVVFGQKRVE------------TIEVTWHGKGSEDKRGQDIRPGIESGSWLYLGGLAVVCERG-MEVAAICAALN-------ISLTSNSD-------C--VEVAELQQQLLWLLYDLGHLKRYPMALGTLGELEEIHRTHPSISCEQ----------LYREAIESARTHYRNHHVYPYTYQGNYYNRLLKYRDAFAAWANAADVIRLYTYQCRDDEEIYKELLDIANELIPYVMK---------TESSG---HSA---------------RSILRDS-----EVFANLLRFYDGICQWEEDSLTPILHIGWAKPLVNNITKF-------------DYDIRSQV-----VIKLPEDLEAEQAKAELARAEQEAKEAKESKEAAGSEAMEGNNNRMA-TKEEKSKNSELPTTLA-----DLTAACGEKILNPDFLLQGGGQPFADQKQ--QPSGGESDNPELHNNNNNSNSNNNNNNHNADKKEAAATTTNATTTSNGSGTSVQLPVSSEANNAGQAQSQVQINDQLGKPQHK----------EAKKEETSDDYDPFEI----MLKRPVITLY-SQKMKGLKDLLLAE-KLNTHAISLQVTAQSVASRKVRGV 700
[Close]
BLAST of menin vs. Ensembl Fly
Match: Mnn1 (gene:FBgn0031885 transcript:FBtr0110978)

HSP 1 Score: 195.282 bits (495), Expect = 1.015e-51
Identity = 215/802 (26.81%), Postives = 353/802 (44.01%), Query Frame = 2 
Query:  104 FPLTNINDILTLFESLLSMSKLENSYEPNIAFVSILLGVIEYKLTHN--------------ADDDENQCENVFINNIDDYASVKILYITFNDVIVLYKKFQSILWEMINCKSPKSEDVNKFLDRCTLKHITDAVYQKLSVGKYKENCHSQSIYSFIQDNSLDSFGLSYTILAITQQLGYKNIWLSLSEDHAWLEYEGNDINNNQSASSNSHKITADVAWSGKNHENKRCGSIDIGIIERSRLYLGGNSVVCSNNRITVAAAITTINPVKGSHSLSLNGYSNRNQIITSCHSSELAYLKRDLLWIAYKMNLLEKYPLALINLADLE---MNYPKNTLNPNGNYFFGLLGLYREAADINLKYYNNSHVYPYLSMANYFYKDGDYQRALTCWRLAANVISKYNYK-SEDWIIYREFFEIATHFVPNIFRLNNKEDDHHSKSSGSVYHASENESTKDRNRVSVDCKSLTCDELKNSVEFLSEFLCFFDFICLWEEGSSVPVLHEVWANKFKEVLCRFSESTRVELNTIGVDANILNEIQSIEEILFLPSNCSKPICQPKHDENESKPMSLVKSRQNSPNKSKRKPIKRLSLSNEELNQIKEFWIALCNNETKNLSTILSSKVLNLDFLLNFNSVKMFELSHILEPIDYENLNCE-------NLCQLKTDKEFIDYFSTFKSVRDILNDNNDRNTSSSINSTQKNIESDQVLQELS-NDQSHRCKYENSSNVPKIILESKSENEINQKSSYKIDSKSCQKIPLMDVFKSQKMKDICPLIVAPGKLNVPAIKLPLTAQSQVSLKRTGL 2431
            FPL +  D++ LF   L+     +  EP++  +SI++G IE  LT                A  D +Q      N+I    SV    +T   +  LYKKFQ+IL  +   + PK    ++   R  +K ++D ++  L    YK+  H Q++YS++  N LD FG++  ++A  Q LGYK++ L++SEDHAW+ +    +             T +V W GK  E+KR   I  GI   S LYLGG +VVC    + VAA    +N       +SL   S+       C   E+A L++ LLW+ Y +  L++YP+AL  L +LE     +P  +             LYREA +    +Y N HVYPY    NY+ +   Y+ A   W  AA+VI  Y Y+  +D  IY+E  +IA   +P + +         ++SSG   H++               +S+  D      E  +  L F+D IC WEE S  P+LH  WA      + +F             D +I +++     ++ LP +      + +    E +     +S++ + +++      R++ + EE ++  E    L      +L+     K+LN DFLL        +     +P   E+ N E       +      +    D      +  +    +N   TS  +  + +   + Q   ++  NDQ  + +++          E+K E   +    ++I      K P++ ++ SQKMK +  L++A  KLN  AI L +TAQS  S K  G+
Sbjct:   24 FPLKSTADVINLFRRALT-----SGIEPDLTLLSIVVGYIELSLTTGEAAAQAAQAAAAAVAAGDISQA-TTGGNDIIMGNSVPFPVVTHELIAGLYKKFQTILSVV---EKPKP---HRQATREVIKKVSDVIWNSLIRSSYKDRAHLQNLYSYLSGNKLDCFGVALAVVAGCQLLGYKDVRLAISEDHAWVVFGQKRVE------------TIEVTWHGKGSEDKRGQDIRPGIESGSWLYLGGLAVVCERG-MEVAAICAALN-------ISLTSNSD-------C--VEVAELQQQLLWLLYDLGHLKRYPMALGTLGELEEIHRTHPSISCEQ----------LYREAIESARTHYRNHHVYPYTYQGNYYNRLLKYRDAFAAWANAADVIRLYTYQCRDDEEIYKELLDIANELIPYVMK---------TESSG---HSA---------------RSILRDS-----EVFANLLRFYDGICQWEEDSLTPILHIGWAKPLVNNITKF-------------DYDIRSQV-----VIKLPEDLEAEQAKAELARAEQEAKEAKESKEAAGSEAMEGNNNRMA-TKEEKSKNSELPTTLA-----DLTAACGEKILNPDFLLQGGGQPFADQKQ--QPSGGESDNPELHNNNNNSNSNNNNNNHNADKKEAAATTTNATTTSNGSGTSVQLPVSSEANNAGQAQSQVQINDQLGKPQHK----------EAKKEETSDDYDPFEI----MLKRPVITLY-SQKMKGLKDLLLAE-KLNTHAISLQVTAQSVASRKVRGV 700
[Close]
BLAST of menin vs. Ensembl Fly
Match: Mnn1 (gene:FBgn0031885 transcript:FBtr0079402)

HSP 1 Score: 181.8 bits (460), Expect = 1.497e-48
Identity = 159/521 (30.52%), Postives = 244/521 (46.83%), Query Frame = 2 
Query:  104 FPLTNINDILTLFESLLSMSKLENSYEPNIAFVSILLGVIEYKLTHN--------------ADDDENQCENVFINNIDDYASVKILYITFNDVIVLYKKFQSILWEMINCKSPKSEDVNKFLDRCTLKHITDAVYQKLSVGKYKENCHSQSIYSFIQDNSLDSFGLSYTILAITQQLGYKNIWLSLSEDHAWLEYEGNDINNNQSASSNSHKITADVAWSGKNHENKRCGSIDIGIIERSRLYLGGNSVVCSNNRITVAAAITTINPVKGSHSLSLNGYSNRNQIITSCHSSELAYLKRDLLWIAYKMNLLEKYPLALINLADLE---MNYPKNTLNPNGNYFFGLLGLYREAADINLKYYNNSHVYPYLSMANYFYKDGDYQRALTCWRLAANVISKYNYK-SEDWIIYREFFEIATHFVPNIFRLNNKEDDHHSKSSGSVYHASENESTKDRNRVSVDCKSLTCDELKNSVEFLSEFLCFFDFICLWEEGSSVPVLHEVWANKFKEVLCRFSESTRVEL 1612
            FPL +  D++ LF   L+     +  EP++  +SI++G IE  LT                A  D +Q      N+I    SV    +T   +  LYKKFQ+IL  +   + PK    ++   R  +K ++D ++  L    YK+  H Q++YS++  N LD FG++  ++A  Q LGYK++ L++SEDHAW+ +    +             T +V W GK  E+KR   I  GI   S LYLGG +VVC    + VAA    +N       +SL   SN + +       E+A L++ LLW+ Y +  L++YP+AL  L +LE     +P  +             LYREA +    +Y N HVYPY    NY+ +   Y+ A   W  AA+VI  Y Y+  +D  IY+E  +IA   +P + +         ++SSG   H++               +S+  D      E  +  L F+D IC WEE S  P+LH  WA      + +F    R ++
Sbjct:   24 FPLKSTADVINLFRRALT-----SGIEPDLTLLSIVVGYIELSLTTGEAAAQAAQAAAAAVAAGDISQA-TTGGNDIIMGNSVPFPVVTHELIAGLYKKFQTILSVV---EKPKP---HRQATREVIKKVSDVIWNSLIRSSYKDRAHLQNLYSYLSGNKLDCFGVALAVVAGCQLLGYKDVRLAISEDHAWVVFGQKRVE------------TIEVTWHGKGSEDKRGQDIRPGIESGSWLYLGGLAVVCERG-MEVAAICAALN-------ISLT--SNSDCV-------EVAELQQQLLWLLYDLGHLKRYPMALGTLGELEEIHRTHPSISCEQ----------LYREAIESARTHYRNHHVYPYTYQGNYYNRLLKYRDAFAAWANAADVIRLYTYQCRDDEEIYKELLDIANELIPYVMK---------TESSG---HSA---------------RSILRDS-----EVFANLLRFYDGICQWEEDSLTPILHIGWAKPLVNNITKFDYDIRSQV 461
[Close]
BLAST of menin vs. Ensembl Zebrafish
Match: men1 (multiple endocrine neoplasia I [Source:ZFIN;Acc:ZDB-GENE-991110-12])

HSP 1 Score: 241.121 bits (614), Expect = 1.264e-68
Identity = 167/521 (32.05%), Postives = 259/521 (49.71%), Query Frame = 2 
Query:   95 KKYFPLTNINDILTLFESLLSMSKLENSYEPNIAFVSILLGVIEYKLTHNADDDENQCENVFINNIDDYASVKILYITFNDVIVLYKKFQSILW---EMINCKSPKSEDVNKFLDRCTLKHITDAVYQKLSVGKYKENCHSQSIYSFIQDNSLDSFGLSYTILAITQQLGYKNIWLSLSEDHAWLEYEGNDINNNQSASSNSHKITADVAWSGKNHENKRCGSIDIGIIERSRLYLGGNSVVCSNNRITVAAAITTINPVKGSHSLSLNGYSNRNQIITSCHSSELAYLKRDLLWIAYKMNLLEKYPLALINLADLEMNYPKNTLNPNGNYFFGLLGLYREAADINLKYYNNSHVYPYLSMANYFYKDGDYQRALTCWRLAANVISKYNYKSEDWIIYREFFEIATHFVPNIFRLNNKEDDHHSKSSGSVYHASENESTKDRNRVSVDCKSLTCDELKNSVEFLSEFLCFFDFICLWEEGSSVPVLHEVWANKFKEVLCRFSESTRVELNTIGVDANILNE 1648
            KK+FPL  I+ ++ LFES L      NS EP++A +S++LG +E+ L  N     N     F     D  +     +  N +  LY++F + +    +M   + P          R  +K ++D ++  LS   +K+  H QS++S I    LDS G+++ ++A  Q LG K++ L+LSEDHAW+ +                + TA+V W GK +E++R  ++  GI ERS LYL G+ + C+ N + VA  +  INP     SL L+             S+EL  L++ LLW+ Y    LE+YP+A+  LADLE   P              L ++ +A +   KYYNN H+YPY+ +A Y Y+  D + AL  W  AA+V+  YNY  ED  IY+EFF+IA   +P + +                  A+E+E T +  +     ++     L++  E  +  L F+D IC WEEGS  PVLH  WA    + L RF    R +++ I  D   +++
Sbjct:    8 KKHFPLRGIDGVVQLFESEL------NSPEPDLALLSLVLGFVEHFLAVNRVVPVNVPGVRFEPLQPDSLNSCFPTVELNLLSALYERFMAQIRGAVDMSQYRKPSGAS-----SRELVKKVSDVIWNSLSRSYFKDRAHIQSLFSLITGTKLDSSGVAFAVVAACQVLGLKDVHLALSEDHAWVIF------------GKGGEETAEVTWHGKGNEDRRGQTVSAGINERSWLYLKGSYMKCNRN-MEVAFMVCAINP-----SLDLH-----------TDSTELIQLQQRLLWLLYDRGDLERYPMAMGTLADLEDQEPMTGKESP-------LSIHLKAVESAKKYYNNEHIYPYMYLAGYHYRHRDVREALGSWAEAASVMQDYNYCREDEEIYKEFFDIANDVIPTLLK--------------ETAAAAESEGTDEAEKEDQPREAAALTALQDP-ECFAHLLRFYDGICKWEEGSPTPVLHVGWATYLVQSLSRFDAQIRQKVSIITKDTEPVDD 466
[Close]
BLAST of menin vs. Ensembl Xenopus
Match: men1 (menin 1 [Source:NCBI gene;Acc:549115])

HSP 1 Score: 203.756 bits (517), Expect = 1.013e-55
Identity = 147/514 (28.60%), Postives = 245/514 (47.67%), Query Frame = 2 
Query:   95 KKYFPLTNINDILTLFESLLSMSKLENSYEPNIAFVSILLGVIEYKLTHNADDDENQCENVFINNIDDYASVKILYITFNDVIV---LYKKFQSILWEMINCKS-PKSEDVNKFLDRCTLKHITDAVYQKLSVGKYKENCHSQSIYSFIQDNSLDSFGLSYTILAITQQLGYKNIWLSLSEDHAWLEYEGNDINNNQSASSNSHKITADVAWSGKNHENKRCGSIDIGIIERSRLYLGGNSVVCSNNRITVAAAITTINPVKGSHSLSLNGYSNRNQIITSCHSSELAYLKRDLLWIAYKMNLLEKYPLALINLADLE-MNYPKNTLNPNGNYFFGLLGLYREAADINLKYYNNSHVYPYLSMANYFYKDGDYQRALTCWRLAANVISKYNYKSEDWIIYREFFEIATHFVPNIFRLNNKEDDHHSKSSGSVYHASENESTKDRNRVSVDCKSLTCDELKNSVEFLSEFLCFFDFICLWEEGSSVPVLHEVWANKFKEVLCRFSESTRVELNTI 1621
            K +FP+T+++ +++LF+  LS        EP++A +S+ LG +E+ L  N     N   N    +  + A + I Y    ++ V   L+ +F +     ++    P+ + V+    R  ++ ++D ++  LS   +K+  H QS++SF+    LDS G+++ ++A  Q LG  ++ L+LSEDHAW+ + G D              TA+V W GK +E++R  S+  G++E+S LYL G  + C +  + VA  +  INP   +H+ SL     + +++                   +    L+KYP+AL NLADLE +       NP        L +Y +A   +  +Y N H+YP++ +A Y  ++ D + AL  W   + VI  YNY  ED  IY++ F+IA   +PN+ +      D  S S+                             L++ V F +  L F+D IC WEE S  PVLH  WA    + L RF    R ++  +
Sbjct:    8 KSFFPITSLDSLVSLFQWELSRP------EPDLALLSLTLGFVEHFLAVNRVVPTNGPSNE--TSKAESARLGIPYFPALELSVAQALHARFTAQTRGAVDLSCYPREDGVS---GRELIRRVSDVIWNGLSRSYFKDRAHIQSLFSFVTGTKLDSPGVAFAVVAACQVLGLSDVHLALSEDHAWVVF-GKDGEQ-----------TAEVTWHGKGNEDRRGQSVSSGVLEKSWLYLNGRYLRC-DRHMEVAFMVCAINPSIDAHTDSLELLQLQQKLLWV----------------LFDGGHLDKYPMALGNLADLEDLAATHGRPNP--------LEIYHKAVSSSRLHYENQHLYPHIYLAAYHCRNKDIREALKAWAETSAVIQTYNYCREDEEIYKDLFDIANDLLPNLLKEEAMSPDGPSGSA-----------------------------LQDPVCF-ANLLRFYDGICKWEEDSPTPVLHVGWATFLVQSLGRFDAQVRQQITLL 443
[Close]
BLAST of menin vs. Ensembl Xenopus
Match: men1 (menin 1 [Source:NCBI gene;Acc:549115])

HSP 1 Score: 183.726 bits (465), Expect = 4.731e-48
Identity = 127/409 (31.05%), Postives = 199/409 (48.66%), Query Frame = 2 
Query:  398 PKSEDVNKFLDRCTLKHITDAVYQKLSVGKYKENCHSQSIYSFIQDNSLDSFGLSYTILAITQQLGYKNIWLSLSEDHAWLEYEGNDINNNQSASSNSHKITADVAWSGKNHENKRCGSIDIGIIERSRLYLGGNSVVCSNNRITVAAAITTINPVKGSHSLSLNGYSNRNQIITSCHSSELAYLKRDLLWIAYKMNLLEKYPLALINLADLE-MNYPKNTLNPNGNYFFGLLGLYREAADINLKYYNNSHVYPYLSMANYFYKDGDYQRALTCWRLAANVISKYNYKSEDWIIYREFFEIATHFVPNIFRLNNKEDDHHSKSSGSVYHASENESTKDRNRVSVDCKSLTCDELKNSVEFLSEFLCFFDFICLWEEGSSVPVLHEVWANKFKEVLCRFSESTRVELNTI 1621
            P+ + V+    R  ++ ++D ++  LS   +K+  H QS++SF+    LDS G+++ ++A  Q LG  ++ L+LSEDHAW+ + G D              TA+V W GK +E++R  S+  G++E+S LYL G  + C +  + VA  +  INP   +H+                 S EL  L++ LLW+ +    L+KYP+AL NLADLE +       NP        L +Y +A   +  +Y N H+YP++ +A Y  ++ D + AL  W   + VI  YNY  ED  IY++ F+IA   +PN+ +      D  S S+                             L++ V F +  L F+D IC WEE S  PVLH  WA    + L RF    R ++  +
Sbjct:  224 PREDGVS---GRELIRRVSDVIWNGLSRSYFKDRAHIQSLFSFVTGTKLDSPGVAFAVVAACQVLGLSDVHLALSEDHAWVVF-GKDGEQ-----------TAEVTWHGKGNEDRRGQSVSSGVLEKSWLYLNGRYLRC-DRHMEVAFMVCAINPSIDAHT----------------DSLELLQLQQKLLWVLFDGGHLDKYPMALGNLADLEDLAATHGRPNP--------LEIYHKAVSSSRLHYENQHLYPHIYLAAYHCRNKDIREALKAWAETSAVIQTYNYCREDEEIYKDLFDIANDLLPNLLKEEAMSPDGPSGSA-----------------------------LQDPVCF-ANLLRFYDGICKWEEDSPTPVLHVGWATFLVQSLGRFDAQVRQQITLL 562
[Close]
BLAST of menin vs. Ensembl Xenopus
Match: men1 (menin 1 [Source:NCBI gene;Acc:549115])

HSP 1 Score: 156.762 bits (395), Expect = 6.518e-40
Identity = 102/311 (32.80%), Postives = 165/311 (53.05%), Query Frame = 2 
Query:  398 PKSEDVNKFLDRCTLKHITDAVYQKLSVGKYKENCHSQSIYSFIQDNSLDSFGLSYTILAITQQLGYKNIWLSLSEDHAWLEYEGNDINNNQSASSNSHKITADVAWSGKNHENKRCGSIDIGIIERSRLYLGGNSVVCSNNRITVAAAITTINPVKGSHSLSLNGYSNRNQIITSCHSSELAYLKRDLLWIAYKMNLLEKYPLALINLADLE-MNYPKNTLNPNGNYFFGLLGLYREAADINLKYYNNSHVYPYLSMANYFYKDGDYQRALTCWRLAANVISKYNYKSEDWIIYREFFEIATHFVPNIFR 1327
            P+ + V+    R  ++ ++D ++  LS   +K+  H QS++SF+    LDS G+++ ++A  Q LG  ++ L+LSEDHAW+ + G D              TA+V W GK +E++R  S+  G++E+S LYL G  + C +  + VA  +  INP   +H+                 S EL  L++ LLW+ +    L+KYP+AL NLADLE +       NP        L +Y +A   +  +Y N H+YP++ +A Y  ++ D + AL  W   + VI  YNY  ED  IY++ F+IA   +PN+ +
Sbjct:  224 PREDGVS---GRELIRRVSDVIWNGLSRSYFKDRAHIQSLFSFVTGTKLDSPGVAFAVVAACQVLGLSDVHLALSEDHAWVVF-GKDGEQ-----------TAEVTWHGKGNEDRRGQSVSSGVLEKSWLYLNGRYLRC-DRHMEVAFMVCAINPSIDAHT----------------DSLELLQLQQKLLWVLFDGGHLDKYPMALGNLADLEDLAATHGRPNP--------LEIYHKAVSSSRLHYENQHLYPHIYLAAYHCRNKDIREALKAWAETSAVIQTYNYCREDEEIYKDLFDIANDLLPNLLK 494
[Close]
BLAST of menin vs. Ensembl Mouse
Match: Men1 (multiple endocrine neoplasia 1 [Source:MGI Symbol;Acc:MGI:1316736])

HSP 1 Score: 226.868 bits (577), Expect = 1.876e-63
Identity = 160/513 (31.19%), Postives = 252/513 (49.12%), Query Frame = 2 
Query:   95 KKYFPLTNINDILTLFESLLSMSKLENSYEPNIAFVSILLGVIEYKLTHNADDDENQCENVFINNIDDYASVKILYITFND---VIVLYKKFQSILWEMINCK-SPKSEDVNKFLDRCTLKHITDAVYQKLSVGKYKENCHSQSIYSFIQDNSLDSFGLSYTILAITQQLGYKNIWLSLSEDHAWLEYEGNDINNNQSASSNSHKITADVAWSGKNHENKRCGSIDIGIIERSRLYLGGNSVVCSNNRITVAAAITTINPVKGSHSLSLNGYSNRNQIITSCHSSELAYLKRDLLWIAYKMNLLEKYPLALINLADLEMNYPKNTLNPNGNYFFGLLGLYREAADINLKYYNNSHVYPYLSMANYFYKDGDYQRALTCWRLAANVISKYNYKSEDWIIYREFFEIATHFVPNIFRLNNKEDDHHSKSSGSVYHASENESTKDRNRVSVDCKSLTCDELKNSVEFLSEFLCFFDFICLWEEGSSVPVLHEVWANKFKEVLCRFSESTRVELNTI 1621
            K  FPL +I+D++ LF + L         EP++  +S++LG +E+ L  N     N  E  F  +        + Y    D   +  LY +F + +   ++    P+   V+    R  +K ++D ++  LS   +K+  H QS++SFI    LDS G+++ ++   Q LG +++ L+LSEDHAW+ +  N             + TA+V W GK +E++R  +++ G+ ERS LYL G+ + C + ++ VA  +  INP     S+ L+             S EL  L++ LLW+ Y +  LE+YP+AL NLADLE   P     P+       L LY +       YY + H+YPY+ +A Y  ++ + + AL  W   A VI  YNY  ED  IY+EFFE+A   +PN+            K + S+    E E T ++ + +    S   D      E  +  L F+D IC WEEGS  PVLH  WA    + L RF    R +++ +
Sbjct:   14 KTLFPLRSIDDVVRLFAAELGRE------EPDLVLLSLVLGFVEHFLAVNRVIPTNVPELTFQPSPAPDPPGGLTYFPVADLSIIAALYARFTAQIRGAVDLSLYPREGGVS---SRELVKKVSDVIWNSLSRSYFKDRAHIQSLFSFITGTKLDSSGVAFAVVGACQALGLRDVHLALSEDHAWVVFGPNG------------EQTAEVTWHGKGNEDRRGQTVNAGVAERSWLYLKGSYMRC-DRKMEVAFMVCAINP-----SIDLH-----------TDSLELLQLQQKLLWLLYDLGHLERYPMALGNLADLEELEPTPG-RPD------PLTLYHKGIASAKTYYQDEHIYPYMYLAGYHCRNRNVREALQAWADTATVIQDYNYCREDEEIYKEFFEVANDVIPNLL-----------KEAASLLETGE-ERTGEQAQGTQGQGSALQDP-----ECFAHLLRFYDGICKWEEGSPTPVLHVGWATFLVQSLGRFEGQVRQKVHIV 464
[Close]
BLAST of menin vs. Ensembl Mouse
Match: Men1 (multiple endocrine neoplasia 1 [Source:MGI Symbol;Acc:MGI:1316736])

HSP 1 Score: 226.868 bits (577), Expect = 1.876e-63
Identity = 160/513 (31.19%), Postives = 252/513 (49.12%), Query Frame = 2 
Query:   95 KKYFPLTNINDILTLFESLLSMSKLENSYEPNIAFVSILLGVIEYKLTHNADDDENQCENVFINNIDDYASVKILYITFND---VIVLYKKFQSILWEMINCK-SPKSEDVNKFLDRCTLKHITDAVYQKLSVGKYKENCHSQSIYSFIQDNSLDSFGLSYTILAITQQLGYKNIWLSLSEDHAWLEYEGNDINNNQSASSNSHKITADVAWSGKNHENKRCGSIDIGIIERSRLYLGGNSVVCSNNRITVAAAITTINPVKGSHSLSLNGYSNRNQIITSCHSSELAYLKRDLLWIAYKMNLLEKYPLALINLADLEMNYPKNTLNPNGNYFFGLLGLYREAADINLKYYNNSHVYPYLSMANYFYKDGDYQRALTCWRLAANVISKYNYKSEDWIIYREFFEIATHFVPNIFRLNNKEDDHHSKSSGSVYHASENESTKDRNRVSVDCKSLTCDELKNSVEFLSEFLCFFDFICLWEEGSSVPVLHEVWANKFKEVLCRFSESTRVELNTI 1621
            K  FPL +I+D++ LF + L         EP++  +S++LG +E+ L  N     N  E  F  +        + Y    D   +  LY +F + +   ++    P+   V+    R  +K ++D ++  LS   +K+  H QS++SFI    LDS G+++ ++   Q LG +++ L+LSEDHAW+ +  N             + TA+V W GK +E++R  +++ G+ ERS LYL G+ + C + ++ VA  +  INP     S+ L+             S EL  L++ LLW+ Y +  LE+YP+AL NLADLE   P     P+       L LY +       YY + H+YPY+ +A Y  ++ + + AL  W   A VI  YNY  ED  IY+EFFE+A   +PN+            K + S+    E E T ++ + +    S   D      E  +  L F+D IC WEEGS  PVLH  WA    + L RF    R +++ +
Sbjct:   14 KTLFPLRSIDDVVRLFAAELGRE------EPDLVLLSLVLGFVEHFLAVNRVIPTNVPELTFQPSPAPDPPGGLTYFPVADLSIIAALYARFTAQIRGAVDLSLYPREGGVS---SRELVKKVSDVIWNSLSRSYFKDRAHIQSLFSFITGTKLDSSGVAFAVVGACQALGLRDVHLALSEDHAWVVFGPNG------------EQTAEVTWHGKGNEDRRGQTVNAGVAERSWLYLKGSYMRC-DRKMEVAFMVCAINP-----SIDLH-----------TDSLELLQLQQKLLWLLYDLGHLERYPMALGNLADLEELEPTPG-RPD------PLTLYHKGIASAKTYYQDEHIYPYMYLAGYHCRNRNVREALQAWADTATVIQDYNYCREDEEIYKEFFEVANDVIPNLL-----------KEAASLLETGE-ERTGEQAQGTQGQGSALQDP-----ECFAHLLRFYDGICKWEEGSPTPVLHVGWATFLVQSLGRFEGQVRQKVHIV 464
[Close]
BLAST of menin vs. Ensembl Mouse
Match: Men1 (multiple endocrine neoplasia 1 [Source:MGI Symbol;Acc:MGI:1316736])

HSP 1 Score: 226.483 bits (576), Expect = 2.175e-63
Identity = 160/513 (31.19%), Postives = 252/513 (49.12%), Query Frame = 2 
Query:   95 KKYFPLTNINDILTLFESLLSMSKLENSYEPNIAFVSILLGVIEYKLTHNADDDENQCENVFINNIDDYASVKILYITFND---VIVLYKKFQSILWEMINCK-SPKSEDVNKFLDRCTLKHITDAVYQKLSVGKYKENCHSQSIYSFIQDNSLDSFGLSYTILAITQQLGYKNIWLSLSEDHAWLEYEGNDINNNQSASSNSHKITADVAWSGKNHENKRCGSIDIGIIERSRLYLGGNSVVCSNNRITVAAAITTINPVKGSHSLSLNGYSNRNQIITSCHSSELAYLKRDLLWIAYKMNLLEKYPLALINLADLEMNYPKNTLNPNGNYFFGLLGLYREAADINLKYYNNSHVYPYLSMANYFYKDGDYQRALTCWRLAANVISKYNYKSEDWIIYREFFEIATHFVPNIFRLNNKEDDHHSKSSGSVYHASENESTKDRNRVSVDCKSLTCDELKNSVEFLSEFLCFFDFICLWEEGSSVPVLHEVWANKFKEVLCRFSESTRVELNTI 1621
            K  FPL +I+D++ LF + L         EP++  +S++LG +E+ L  N     N  E  F  +        + Y    D   +  LY +F + +   ++    P+   V+    R  +K ++D ++  LS   +K+  H QS++SFI    LDS G+++ ++   Q LG +++ L+LSEDHAW+ +  N             + TA+V W GK +E++R  +++ G+ ERS LYL G+ + C + ++ VA  +  INP     S+ L+             S EL  L++ LLW+ Y +  LE+YP+AL NLADLE   P     P+       L LY +       YY + H+YPY+ +A Y  ++ + + AL  W   A VI  YNY  ED  IY+EFFE+A   +PN+            K + S+    E E T ++ + +    S   D      E  +  L F+D IC WEEGS  PVLH  WA    + L RF    R +++ +
Sbjct:    8 KTLFPLRSIDDVVRLFAAELGRE------EPDLVLLSLVLGFVEHFLAVNRVIPTNVPELTFQPSPAPDPPGGLTYFPVADLSIIAALYARFTAQIRGAVDLSLYPREGGVS---SRELVKKVSDVIWNSLSRSYFKDRAHIQSLFSFITGTKLDSSGVAFAVVGACQALGLRDVHLALSEDHAWVVFGPNG------------EQTAEVTWHGKGNEDRRGQTVNAGVAERSWLYLKGSYMRC-DRKMEVAFMVCAINP-----SIDLH-----------TDSLELLQLQQKLLWLLYDLGHLERYPMALGNLADLEELEPTPG-RPD------PLTLYHKGIASAKTYYQDEHIYPYMYLAGYHCRNRNVREALQAWADTATVIQDYNYCREDEEIYKEFFEVANDVIPNLL-----------KEAASLLETGE-ERTGEQAQGTQGQGSALQDP-----ECFAHLLRFYDGICKWEEGSPTPVLHVGWATFLVQSLGRFEGQVRQKVHIV 458
[Close]
BLAST of menin vs. Ensembl Mouse
Match: Men1 (multiple endocrine neoplasia 1 [Source:MGI Symbol;Acc:MGI:1316736])

HSP 1 Score: 226.483 bits (576), Expect = 2.175e-63
Identity = 160/513 (31.19%), Postives = 252/513 (49.12%), Query Frame = 2 
Query:   95 KKYFPLTNINDILTLFESLLSMSKLENSYEPNIAFVSILLGVIEYKLTHNADDDENQCENVFINNIDDYASVKILYITFND---VIVLYKKFQSILWEMINCK-SPKSEDVNKFLDRCTLKHITDAVYQKLSVGKYKENCHSQSIYSFIQDNSLDSFGLSYTILAITQQLGYKNIWLSLSEDHAWLEYEGNDINNNQSASSNSHKITADVAWSGKNHENKRCGSIDIGIIERSRLYLGGNSVVCSNNRITVAAAITTINPVKGSHSLSLNGYSNRNQIITSCHSSELAYLKRDLLWIAYKMNLLEKYPLALINLADLEMNYPKNTLNPNGNYFFGLLGLYREAADINLKYYNNSHVYPYLSMANYFYKDGDYQRALTCWRLAANVISKYNYKSEDWIIYREFFEIATHFVPNIFRLNNKEDDHHSKSSGSVYHASENESTKDRNRVSVDCKSLTCDELKNSVEFLSEFLCFFDFICLWEEGSSVPVLHEVWANKFKEVLCRFSESTRVELNTI 1621
            K  FPL +I+D++ LF + L         EP++  +S++LG +E+ L  N     N  E  F  +        + Y    D   +  LY +F + +   ++    P+   V+    R  +K ++D ++  LS   +K+  H QS++SFI    LDS G+++ ++   Q LG +++ L+LSEDHAW+ +  N             + TA+V W GK +E++R  +++ G+ ERS LYL G+ + C + ++ VA  +  INP     S+ L+             S EL  L++ LLW+ Y +  LE+YP+AL NLADLE   P     P+       L LY +       YY + H+YPY+ +A Y  ++ + + AL  W   A VI  YNY  ED  IY+EFFE+A   +PN+            K + S+    E E T ++ + +    S   D      E  +  L F+D IC WEEGS  PVLH  WA    + L RF    R +++ +
Sbjct:    8 KTLFPLRSIDDVVRLFAAELGRE------EPDLVLLSLVLGFVEHFLAVNRVIPTNVPELTFQPSPAPDPPGGLTYFPVADLSIIAALYARFTAQIRGAVDLSLYPREGGVS---SRELVKKVSDVIWNSLSRSYFKDRAHIQSLFSFITGTKLDSSGVAFAVVGACQALGLRDVHLALSEDHAWVVFGPNG------------EQTAEVTWHGKGNEDRRGQTVNAGVAERSWLYLKGSYMRC-DRKMEVAFMVCAINP-----SIDLH-----------TDSLELLQLQQKLLWLLYDLGHLERYPMALGNLADLEELEPTPG-RPD------PLTLYHKGIASAKTYYQDEHIYPYMYLAGYHCRNRNVREALQAWADTATVIQDYNYCREDEEIYKEFFEVANDVIPNLL-----------KEAASLLETGE-ERTGEQAQGTQGQGSALQDP-----ECFAHLLRFYDGICKWEEGSPTPVLHVGWATFLVQSLGRFEGQVRQKVHIV 458
[Close]
BLAST of menin vs. Ensembl Mouse
Match: Men1 (multiple endocrine neoplasia 1 [Source:MGI Symbol;Acc:MGI:1316736])

HSP 1 Score: 226.483 bits (576), Expect = 2.175e-63
Identity = 160/513 (31.19%), Postives = 252/513 (49.12%), Query Frame = 2 
Query:   95 KKYFPLTNINDILTLFESLLSMSKLENSYEPNIAFVSILLGVIEYKLTHNADDDENQCENVFINNIDDYASVKILYITFND---VIVLYKKFQSILWEMINCK-SPKSEDVNKFLDRCTLKHITDAVYQKLSVGKYKENCHSQSIYSFIQDNSLDSFGLSYTILAITQQLGYKNIWLSLSEDHAWLEYEGNDINNNQSASSNSHKITADVAWSGKNHENKRCGSIDIGIIERSRLYLGGNSVVCSNNRITVAAAITTINPVKGSHSLSLNGYSNRNQIITSCHSSELAYLKRDLLWIAYKMNLLEKYPLALINLADLEMNYPKNTLNPNGNYFFGLLGLYREAADINLKYYNNSHVYPYLSMANYFYKDGDYQRALTCWRLAANVISKYNYKSEDWIIYREFFEIATHFVPNIFRLNNKEDDHHSKSSGSVYHASENESTKDRNRVSVDCKSLTCDELKNSVEFLSEFLCFFDFICLWEEGSSVPVLHEVWANKFKEVLCRFSESTRVELNTI 1621
            K  FPL +I+D++ LF + L         EP++  +S++LG +E+ L  N     N  E  F  +        + Y    D   +  LY +F + +   ++    P+   V+    R  +K ++D ++  LS   +K+  H QS++SFI    LDS G+++ ++   Q LG +++ L+LSEDHAW+ +  N             + TA+V W GK +E++R  +++ G+ ERS LYL G+ + C + ++ VA  +  INP     S+ L+             S EL  L++ LLW+ Y +  LE+YP+AL NLADLE   P     P+       L LY +       YY + H+YPY+ +A Y  ++ + + AL  W   A VI  YNY  ED  IY+EFFE+A   +PN+            K + S+    E E T ++ + +    S   D      E  +  L F+D IC WEEGS  PVLH  WA    + L RF    R +++ +
Sbjct:    8 KTLFPLRSIDDVVRLFAAELGRE------EPDLVLLSLVLGFVEHFLAVNRVIPTNVPELTFQPSPAPDPPGGLTYFPVADLSIIAALYARFTAQIRGAVDLSLYPREGGVS---SRELVKKVSDVIWNSLSRSYFKDRAHIQSLFSFITGTKLDSSGVAFAVVGACQALGLRDVHLALSEDHAWVVFGPNG------------EQTAEVTWHGKGNEDRRGQTVNAGVAERSWLYLKGSYMRC-DRKMEVAFMVCAINP-----SIDLH-----------TDSLELLQLQQKLLWLLYDLGHLERYPMALGNLADLEELEPTPG-RPD------PLTLYHKGIASAKTYYQDEHIYPYMYLAGYHCRNRNVREALQAWADTATVIQDYNYCREDEEIYKEFFEVANDVIPNLL-----------KEAASLLETGE-ERTGEQAQGTQGQGSALQDP-----ECFAHLLRFYDGICKWEEGSPTPVLHVGWATFLVQSLGRFEGQVRQKVHIV 458
[Close]
BLAST of menin vs. UniProt/SwissProt
Match: sp|Q9WVR8|MEN1_RAT (Menin OS=Rattus norvegicus OX=10116 GN=Men1 PE=1 SV=1)

HSP 1 Score: 228.024 bits (580), Expect = 4.388e-63
Identity = 159/513 (30.99%), Postives = 249/513 (48.54%), Query Frame = 2 
Query:   95 KKYFPLTNINDILTLFESLLSMSKLENSYEPNIAFVSILLGVIEYKLTHNADDDENQCENVFINNIDDYASVKILYITFND---VIVLYKKFQSILWEMINCK-SPKSEDVNKFLDRCTLKHITDAVYQKLSVGKYKENCHSQSIYSFIQDNSLDSFGLSYTILAITQQLGYKNIWLSLSEDHAWLEYEGNDINNNQSASSNSHKITADVAWSGKNHENKRCGSIDIGIIERSRLYLGGNSVVCSNNRITVAAAITTINPVKGSHSLSLNGYSNRNQIITSCHSSELAYLKRDLLWIAYKMNLLEKYPLALINLADLEMNYPKNTLNPNGNYFFGLLGLYREAADINLKYYNNSHVYPYLSMANYFYKDGDYQRALTCWRLAANVISKYNYKSEDWIIYREFFEIATHFVPNIFRLNNKEDDHHSKSSGSVYHASENESTKDRNRVSVDCKSLTCDELKNSVEFLSEFLCFFDFICLWEEGSSVPVLHEVWANKFKEVLCRFSESTRVELNTI 1621
            K  FPL +I+D++ LF + L         EP++  +S++LG +E+ L  N     N  E  F  +        + Y    D   +  LY +F + +   ++    P+   V+    R  +K ++D ++  LS   +K+  H QS++SFI    LDS G+++ ++   Q LG +++ L+LSEDHAW+ +            SN  + TA+V W GK +E++R  +++ G+ ERS LYL G+ + C + ++ VA  +  INP     S+ L+             S EL  L++ LLW+ Y +  LE+YP+AL NLADLE   P     P+       L LY +       YY + H+YPY+ +A Y  ++ + + AL  W   A VI  YNY  ED  IY+EFFE+A   +PN+            K + S+  A E    +          +L         E  +  L F+D IC WEEGS  PVLH  WA    + L RF    R +++ +
Sbjct:    8 KTLFPLRSIDDVVRLFAAELGRE------EPDLVLLSLVLGFVEHFLAVNRVIPTNVPELTFQPSPAPDPPGGLTYFPVADLSIIAALYARFTAQIRGAVDLSLYPREGGVS---SRELVKKVSDVIWNSLSRSYFKDRAHIQSLFSFITGTKLDSSGVAFAVVGACQALGLRDVHLALSEDHAWVVF-----------GSNGEQ-TAEVTWHGKGNEDRRGQTVNAGVAERSWLYLKGSYMRC-DRKMEVAFMVCAINP-----SIDLH-----------TDSLELLQLQQKLLWLLYDLGHLERYPMALGNLADLEELEPTPG-RPD------PLTLYHKGIASAKTYYQDEHIYPYMYLAGYHCRNRNVREALQAWADTATVIQDYNYCREDEEIYKEFFEVANDVIPNLL-----------KEAASLLEAGEERPGEQAQGTQGQGSAL------QDPECFAHLLRFYDGICKWEEGSPTPVLHVGWATFLVQSLGRFEGQVRQKVHIV 458
[Close]
BLAST of menin vs. UniProt/SwissProt
Match: sp|Q0P5I0|MEN1_BOVIN (Menin OS=Bos taurus OX=9913 GN=MEN1 PE=2 SV=1)

HSP 1 Score: 227.254 bits (578), Expect = 7.552e-63
Identity = 158/513 (30.80%), Postives = 247/513 (48.15%), Query Frame = 2 
Query:   95 KKYFPLTNINDILTLFESLLSMSKLENSYEPNIAFVSILLGVIEYKLTHNADDDENQCENVFINNIDDYASVKILYITFND---VIVLYKKFQSILWEMINCK-SPKSEDVNKFLDRCTLKHITDAVYQKLSVGKYKENCHSQSIYSFIQDNSLDSFGLSYTILAITQQLGYKNIWLSLSEDHAWLEYEGNDINNNQSASSNSHKITADVAWSGKNHENKRCGSIDIGIIERSRLYLGGNSVVCSNNRITVAAAITTINPVKGSHSLSLNGYSNRNQIITSCHSSELAYLKRDLLWIAYKMNLLEKYPLALINLADLEMNYPKNTLNPNGNYFFGLLGLYREAADINLKYYNNSHVYPYLSMANYFYKDGDYQRALTCWRLAANVISKYNYKSEDWIIYREFFEIATHFVPNIFRLNNKEDDHHSKSSGSVYHASENESTKDRNRVSVDCKSLTCDELKNSVEFLSEFLCFFDFICLWEEGSSVPVLHEVWANKFKEVLCRFSESTRVELNTI 1621
            K  FPL +I+D++ LF + L         EP++  +S++LG +E+ L  N     N  E  F  +        + Y    D   +  LY +F + +   ++    P+   V+    R  +K ++D ++  LS   +K+  H QS++SFI    LDS G+++ ++   Q LG +++ L+LSEDHAW+ +  N             + TA+V W GK +E++R  +++ G+ ERS LYL G+ + C + ++ VA  +  INP     S+ L+             S EL  L++ LLW+ Y +  LE+YP+AL NLADLE   P     P+       L LY +       YY + H+YPY+ +A Y  ++ + + AL  W   A VI  YNY  ED  IY+EFFE+A   +PN+            K + S+  A E    +          +L         E  +  L F+D IC WEEGS  PVLH  WA    + L RF    R ++  +
Sbjct:    8 KTLFPLRSIDDVVRLFAAELGRE------EPDLVLLSLVLGFVEHFLAVNRVIPTNVPELTFQPSPAPDPPGGLTYFPVADLSIIAALYARFTAQIRGAVDLSLYPREGGVS---SRELVKKVSDVIWNSLSRSYFKDRAHIQSLFSFITGTKLDSSGVAFAVVGACQALGLRDVHLALSEDHAWVVFGPNG------------EQTAEVTWHGKGNEDRRGQTVNAGVAERSWLYLKGSYMRC-DRKMEVAFMVCAINP-----SIDLH-----------TDSLELLQLQQKLLWLLYDLGHLERYPMALGNLADLEELEPTPG-RPD------PLTLYHKGIASAKTYYRDEHIYPYMYLAGYHCRNRNVREALQAWADTATVIQDYNYCREDEEIYKEFFEVANDVIPNLL-----------KEAASLLEAGEERPGEQTQGTQSQGSAL------QDPECFAHLLRFYDGICKWEEGSPTPVLHVGWATFLVQSLGRFEGQVRQKVRIV 458
[Close]
BLAST of menin vs. UniProt/SwissProt
Match: sp|O88559|MEN1_MOUSE (Menin OS=Mus musculus OX=10090 GN=Men1 PE=1 SV=2)

HSP 1 Score: 226.483 bits (576), Expect = 1.522e-62
Identity = 160/513 (31.19%), Postives = 252/513 (49.12%), Query Frame = 2 
Query:   95 KKYFPLTNINDILTLFESLLSMSKLENSYEPNIAFVSILLGVIEYKLTHNADDDENQCENVFINNIDDYASVKILYITFND---VIVLYKKFQSILWEMINCK-SPKSEDVNKFLDRCTLKHITDAVYQKLSVGKYKENCHSQSIYSFIQDNSLDSFGLSYTILAITQQLGYKNIWLSLSEDHAWLEYEGNDINNNQSASSNSHKITADVAWSGKNHENKRCGSIDIGIIERSRLYLGGNSVVCSNNRITVAAAITTINPVKGSHSLSLNGYSNRNQIITSCHSSELAYLKRDLLWIAYKMNLLEKYPLALINLADLEMNYPKNTLNPNGNYFFGLLGLYREAADINLKYYNNSHVYPYLSMANYFYKDGDYQRALTCWRLAANVISKYNYKSEDWIIYREFFEIATHFVPNIFRLNNKEDDHHSKSSGSVYHASENESTKDRNRVSVDCKSLTCDELKNSVEFLSEFLCFFDFICLWEEGSSVPVLHEVWANKFKEVLCRFSESTRVELNTI 1621
            K  FPL +I+D++ LF + L         EP++  +S++LG +E+ L  N     N  E  F  +        + Y    D   +  LY +F + +   ++    P+   V+    R  +K ++D ++  LS   +K+  H QS++SFI    LDS G+++ ++   Q LG +++ L+LSEDHAW+ +  N             + TA+V W GK +E++R  +++ G+ ERS LYL G+ + C + ++ VA  +  INP     S+ L+             S EL  L++ LLW+ Y +  LE+YP+AL NLADLE   P     P+       L LY +       YY + H+YPY+ +A Y  ++ + + AL  W   A VI  YNY  ED  IY+EFFE+A   +PN+            K + S+    E E T ++ + +    S   D      E  +  L F+D IC WEEGS  PVLH  WA    + L RF    R +++ +
Sbjct:    8 KTLFPLRSIDDVVRLFAAELGRE------EPDLVLLSLVLGFVEHFLAVNRVIPTNVPELTFQPSPAPDPPGGLTYFPVADLSIIAALYARFTAQIRGAVDLSLYPREGGVS---SRELVKKVSDVIWNSLSRSYFKDRAHIQSLFSFITGTKLDSSGVAFAVVGACQALGLRDVHLALSEDHAWVVFGPNG------------EQTAEVTWHGKGNEDRRGQTVNAGVAERSWLYLKGSYMRC-DRKMEVAFMVCAINP-----SIDLH-----------TDSLELLQLQQKLLWLLYDLGHLERYPMALGNLADLEELEPTPG-RPD------PLTLYHKGIASAKTYYQDEHIYPYMYLAGYHCRNRNVREALQAWADTATVIQDYNYCREDEEIYKEFFEVANDVIPNLL-----------KEAASLLETGE-ERTGEQAQGTQGQGSALQDP-----ECFAHLLRFYDGICKWEEGSPTPVLHVGWATFLVQSLGRFEGQVRQKVHIV 458
[Close]
BLAST of menin vs. UniProt/SwissProt
Match: sp|A2SXS5|MEN1_CANLF (Menin OS=Canis lupus familiaris OX=9615 GN=MEN1 PE=2 SV=1)

HSP 1 Score: 223.016 bits (567), Expect = 2.490e-61
Identity = 160/518 (30.89%), Postives = 249/518 (48.07%), Query Frame = 2 
Query:   95 KKYFPLTNINDILTLFESLLSMSKLENSYEPNIAFVSILLGVIEYKLTHNADDDENQCENVFINNIDDYASVKILYITFND---VIVLYKKFQSILWEMINCK-SPKSEDVNKFLDRCTLKHITDAVYQKLSVGKYKENCHSQSIYSFIQDNS-----LDSFGLSYTILAITQQLGYKNIWLSLSEDHAWLEYEGNDINNNQSASSNSHKITADVAWSGKNHENKRCGSIDIGIIERSRLYLGGNSVVCSNNRITVAAAITTINPVKGSHSLSLNGYSNRNQIITSCHSSELAYLKRDLLWIAYKMNLLEKYPLALINLADLEMNYPKNTLNPNGNYFFGLLGLYREAADINLKYYNNSHVYPYLSMANYFYKDGDYQRALTCWRLAANVISKYNYKSEDWIIYREFFEIATHFVPNIFRLNNKEDDHHSKSSGSVYHASENESTKDRNRVSVDCKSLTCDELKNSVEFLSEFLCFFDFICLWEEGSSVPVLHEVWANKFKEVLCRFSESTRVELNTI 1621
            K  FPL +I+D++ LF + L         EP++  +S++LG +E+ L  N     N  E  F  +        + Y    D   +  LY +F + +   ++    P+   V+    R  +K ++D ++  LS   +K+  H QS++SFI   S     LDS G+++ ++   Q LG +++ L+LSEDHAW+ +  N             + TA+V W GK +E++R  +++ G+ ERS LYL G+ + C + ++ VA  +  INP     S+ L+             S EL  L++ LLW+ Y +  LE+YP+AL NLADLE   P     P+       L LY +       YY + H+YPY+ +A Y  ++ + + AL  W   A VI  YNY  ED  IY+EFFE+A   +PN+            K + S+  A E    +    V     +L         E  +  L F+D IC WEEGS  PVLH  WA    + L RF    R ++  +
Sbjct:    8 KTLFPLRSIDDVVRLFAAELGRE------EPDLVLLSLVLGFVEHFLAVNRVIPTNVPELTFQPSPAPDPPGGLTYFPVADLSIIAALYARFTAQIRGAVDLSLYPREGGVS---SRELVKKVSDVIWNSLSRSYFKDRAHIQSLFSFITGWSPTGTKLDSSGVAFAVVGACQALGLRDVHLALSEDHAWVVFGPNG------------EQTAEVTWHGKGNEDRRGQTVNAGVAERSWLYLKGSYMRC-DRKMEVAFMVCAINP-----SIDLH-----------TDSLELLQLQQKLLWLLYDLGHLERYPMALGNLADLEELEPTPG-RPD------PLTLYHKGIASAKTYYRDEHIYPYMYLAGYHCRNRNVREALQAWADTATVIQDYNYCREDEEIYKEFFEVANDVIPNLL-----------KEAASLLEAGEERPGEQTQGVQSQGSAL------QDPECFAHLLRFYDGICKWEEGSPTPVLHVGWATFLVQSLGRFEGQVRQKVRIV 463
[Close]
BLAST of menin vs. UniProt/SwissProt
Match: sp|O00255|MEN1_HUMAN (Menin OS=Homo sapiens OX=9606 GN=MEN1 PE=1 SV=4)

HSP 1 Score: 221.476 bits (563), Expect = 9.654e-61
Identity = 159/518 (30.69%), Postives = 248/518 (47.88%), Query Frame = 2 
Query:   95 KKYFPLTNINDILTLFESLLSMSKLENSYEPNIAFVSILLGVIEYKLTHNADDDENQCENVFINNIDDYASVKILYITFND---VIVLYKKFQSILWEMINCK-SPKSEDVNKFLDRCTLKHITDAVYQKLSVGKYKENCHSQSIYSFIQDNS-----LDSFGLSYTILAITQQLGYKNIWLSLSEDHAWLEYEGNDINNNQSASSNSHKITADVAWSGKNHENKRCGSIDIGIIERSRLYLGGNSVVCSNNRITVAAAITTINPVKGSHSLSLNGYSNRNQIITSCHSSELAYLKRDLLWIAYKMNLLEKYPLALINLADLEMNYPKNTLNPNGNYFFGLLGLYREAADINLKYYNNSHVYPYLSMANYFYKDGDYQRALTCWRLAANVISKYNYKSEDWIIYREFFEIATHFVPNIFRLNNKEDDHHSKSSGSVYHASENESTKDRNRVSVDCKSLTCDELKNSVEFLSEFLCFFDFICLWEEGSSVPVLHEVWANKFKEVLCRFSESTRVELNTI 1621
            K  FPL +I+D++ LF + L         EP++  +S++LG +E+ L  N     N  E  F  +        + Y    D   +  LY +F + +   ++    P+   V+    R  +K ++D ++  LS   +K+  H QS++SFI   S     LDS G+++ ++   Q LG +++ L+LSEDHAW+ +  N             + TA+V W GK +E++R  +++ G+ ERS LYL G+ + C + ++ VA  +  INP     S+ L+             S EL  L++ LLW+ Y +  LE+YP+AL NLADLE   P     P+       L LY +       YY + H+YPY+ +A Y  ++ + + AL  W   A VI  YNY  ED  IY+EFFE+A   +PN+            K + S+  A E    +          +L         E  +  L F+D IC WEEGS  PVLH  WA    + L RF    R ++  +
Sbjct:    8 KTLFPLRSIDDVVRLFAAELGRE------EPDLVLLSLVLGFVEHFLAVNRVIPTNVPELTFQPSPAPDPPGGLTYFPVADLSIIAALYARFTAQIRGAVDLSLYPREGGVS---SRELVKKVSDVIWNSLSRSYFKDRAHIQSLFSFITGWSPVGTKLDSSGVAFAVVGACQALGLRDVHLALSEDHAWVVFGPNG------------EQTAEVTWHGKGNEDRRGQTVNAGVAERSWLYLKGSYMRC-DRKMEVAFMVCAINP-----SIDLH-----------TDSLELLQLQQKLLWLLYDLGHLERYPMALGNLADLEELEPTPG-RPD------PLTLYHKGIASAKTYYRDEHIYPYMYLAGYHCRNRNVREALQAWADTATVIQDYNYCREDEEIYKEFFEVANDVIPNLL-----------KEAASLLEAGEERPGEQSQGTQSQGSAL------QDPECFAHLLRFYDGICKWEEGSPTPVLHVGWATFLVQSLGRFEGQVRQKVRIV 463
[Close]
BLAST of menin vs. TrEMBL
Match: L0HB44 (Menin (Fragment) OS=Schmidtea mediterranea OX=79327 PE=2 SV=1)

HSP 1 Score: 1238.79 bits (3204), Expect = 0.000e+0
Identity = 604/605 (99.83%), Postives = 605/605 (100.00%), Query Frame = 2 
Query:  575 AITQQLGYKNIWLSLSEDHAWLEYEGNDINNNQSASSNSHKITADVAWSGKNHENKRCGSIDIGIIERSRLYLGGNSVVCSNNRITVAAAITTINPVKGSHSLSLNGYSNRNQIITSCHSSELAYLKRDLLWIAYKMNLLEKYPLALINLADLEMNYPKNTLNPNGNYFFGLLGLYREAADINLKYYNNSHVYPYLSMANYFYKDGDYQRALTCWRLAANVISKYNYKSEDWIIYREFFEIATHFVPNIFRLNNKEDDHHSKSSGSVYHASENESTKDRNRVSVDCKSLTCDELKNSVEFLSEFLCFFDFICLWEEGSSVPVLHEVWANKFKEVLCRFSESTRVELNTIGVDANILNEIQSIEEILFLPSNCSKPICQPKHDENESKPMSLVKSRQNSPNKSKRKPIKRLSLSNEELNQIKEFWIALCNNETKNLSTILSSKVLNLDFLLNFNSVKMFELSHILEPIDYENLNCENLCQLKTDKEFIDYFSTFKSVRDILNDNNDRNTSSSINSTQKNIESDQVLQELSNDQSHRCKYENSSNVPKIILESKSENEINQKSSYKIDSKSCQKIPLMDVFKSQKMKDICPLIVAPGKLNVPAIKLP 2389
            AITQQLGYKNIWLSLSEDHAWLEYEGNDINNNQSAS+NSHKITADVAWSGKNHENKRCGSIDIGIIERSRLYLGGNSVVCSNNRITVAAAITTINPVKGSHSLSLNGYSNRNQIITSCHSSELAYLKRDLLWIAYKMNLLEKYPLALINLADLEMNYPKNTLNPNGNYFFGLLGLYREAADINLKYYNNSHVYPYLSMANYFYKDGDYQRALTCWRLAANVISKYNYKSEDWIIYREFFEIATHFVPNIFRLNNKEDDHHSKSSGSVYHASENESTKDRNRVSVDCKSLTCDELKNSVEFLSEFLCFFDFICLWEEGSSVPVLHEVWANKFKEVLCRFSESTRVELNTIGVDANILNEIQSIEEILFLPSNCSKPICQPKHDENESKPMSLVKSRQNSPNKSKRKPIKRLSLSNEELNQIKEFWIALCNNETKNLSTILSSKVLNLDFLLNFNSVKMFELSHILEPIDYENLNCENLCQLKTDKEFIDYFSTFKSVRDILNDNNDRNTSSSINSTQKNIESDQVLQELSNDQSHRCKYENSSNVPKIILESKSENEINQKSSYKIDSKSCQKIPLMDVFKSQKMKDICPLIVAPGKLNVPAIKLP
Sbjct:    1 AITQQLGYKNIWLSLSEDHAWLEYEGNDINNNQSASTNSHKITADVAWSGKNHENKRCGSIDIGIIERSRLYLGGNSVVCSNNRITVAAAITTINPVKGSHSLSLNGYSNRNQIITSCHSSELAYLKRDLLWIAYKMNLLEKYPLALINLADLEMNYPKNTLNPNGNYFFGLLGLYREAADINLKYYNNSHVYPYLSMANYFYKDGDYQRALTCWRLAANVISKYNYKSEDWIIYREFFEIATHFVPNIFRLNNKEDDHHSKSSGSVYHASENESTKDRNRVSVDCKSLTCDELKNSVEFLSEFLCFFDFICLWEEGSSVPVLHEVWANKFKEVLCRFSESTRVELNTIGVDANILNEIQSIEEILFLPSNCSKPICQPKHDENESKPMSLVKSRQNSPNKSKRKPIKRLSLSNEELNQIKEFWIALCNNETKNLSTILSSKVLNLDFLLNFNSVKMFELSHILEPIDYENLNCENLCQLKTDKEFIDYFSTFKSVRDILNDNNDRNTSSSINSTQKNIESDQVLQELSNDQSHRCKYENSSNVPKIILESKSENEINQKSSYKIDSKSCQKIPLMDVFKSQKMKDICPLIVAPGKLNVPAIKLP 605
[Close]
BLAST of menin vs. TrEMBL
Match: C3ZKP7 (Uncharacterized protein OS=Branchiostoma floridae OX=7739 GN=BRAFLDRAFT_240022 PE=4 SV=1)

HSP 1 Score: 288.5 bits (737), Expect = 1.129e-82
Identity = 182/524 (34.73%), Postives = 272/524 (51.91%), Query Frame = 2 
Query:   95 KKYFPLTNINDILTLFESLLSMSKLENSYEPNIAFVSILLGVIEYKLTHNADDDENQCENVFINNIDDYASVKILY--ITFNDVIVLYKKFQSILWEMINCKSPKSEDVNKF----LDRCTLKHITDAVYQKLSVGKYKENCHSQSIYSFIQDNSLDSFGLSYTILAITQQLGYKNIWLSLSEDHAWLEYEGNDINNNQSASSNSHKITADVAWSGKNHENKRCGSIDIGIIERSRLYLGGNSVVCSNNRITVAAAITTINPVKGSHSLSLNGYSNRNQIITSCHSSELAYLKRDLLWIAYKMNLLEKYPLALINLADLEMNYPKNTLNPNGNYFFGLLGLYREAADINLKYYNNSHVYPYLSMANYFYKDGDYQRALTCWRLAANVISKYNYKSEDWIIYREFFEIATHFVPNIFRLNNKEDDHHSKSSGSVYHASENESTKDRNRVSVDCKSLTCDELKNSVEFLSEFLCFFDFICLWEEGSSVPVLHEVWANKFKEVLCRFSESTRVELNT--IGVDANIL 1642
            K++FPL +I  ++ LF S LS S      EPN+A +S+ LG IE  LT+N            +N +D  A+++ ++  +    V  LY KF         C+   S D++ F      R  +K ++D ++  LS   + +  H QS+YS++  N LD FG+++ ++A  Q LGYK++ L+LSEDHAW+ +       ++ A       TA+V W GK +E+KR   I +G+ E+S LYL G  V C+ + + VAA ++ INP   SH+ S+                E+A L+++LLW+ Y+M  L KYP+AL NLADLE   P     P+       + L+ E       YYNN HVYPY  +  ++Y+ G ++ AL CW  AANVI  YNY  ED  IY+EF EIA   +PN+     K     +  S ++  AS  + + +++       ++    L N  E  +  L  +D IC WEEGSS PVLH  WA    + +  FS   R +LN   IG    +L
Sbjct:    9 KRHFPLQDIKSVVELFRSQLSCS-----VEPNLALLSVTLGYIENVLTNNRA----------LNKVDSGANLEPIFPVVELAPVEALYHKFV--------CQIKGSVDLSLFTHGVATRDLVKKVSDVIWSSLSRSYHTDRAHLQSLYSYLTGNRLDCFGVAFAVVAACQVLGYKDVHLALSEDHAWVTF------GDKGAE------TAEVTWHGKGNEDKRGQPISVGVAEKSWLYLYGFPVQCTRS-MEVAAMVSAINPSIDSHTDSI----------------EMASLQQELLWLLYEMGHLRKYPMALGNLADLEEIDPTPDKPPS-------IQLFHEGIHAGKVYYNNQHVYPYTYLGGHYYRRGQFKDALHCWAQAANVIRSYNYNREDEEIYKEFLEIAHELIPNML----KSVSLSTLQSPALSPASSTDDSSEKSNGRSTPVAVPLSPLLNDPECFAYLLQLYDGICQWEEGSSTPVLHIGWAKHIVQSINSFSPQVRSKLNILLIGDQGEVL 469
[Close]
BLAST of menin vs. TrEMBL
Match: K1P0F7 (Menin OS=Crassostrea gigas OX=29159 GN=CGI_10002230 PE=4 SV=1)

HSP 1 Score: 278.485 bits (711), Expect = 5.012e-78
Identity = 176/524 (33.59%), Postives = 270/524 (51.53%), Query Frame = 2 
Query:   86 NKLKKYFPLTNINDILTLFESLLSMSKLENSYEPNIAFVSILLGVIEYKLTHNADDDENQCENVFINNIDDYASVKILY--ITFNDVIVLYKKFQSILWEMINCKSPKSEDVNKF----LDRCTLKHITDAVYQKLSVGKYKENCHSQSIYSFIQDNSLDSFGLSYTILAITQQLGYKNIWLSLSEDHAWLEYEGNDINNNQSASSNSHKITADVAWSGKNHENKRCGSIDIGIIERSRLYLGGNSVVCSNNRITVAAAITTINPVKGSHSLSLNGYSNRNQIITSCHSSELAYLKRDLLWIAYKMNLLEKYPLALINLADLEMNYP-KNTLNPNGNYFFGLLGLYREAADINLKYYNNSHVYPYLSMANYFYKDGDYQRALTCWRLAANVISKYNYKSEDWIIYREFFEIATHFVPNIFRLNNKEDDHHSKSSGSVYHASENESTKDRNRVSVDCKSLTCDELKNSVEFLSEFLCFFDFICLWEEGSSVPVLHEVWANKFKEVLCRFSESTRVELNTIGVDAN 1636
            ++ K++FPL NI D++ LF   L+  +     EPN++ +SI+LGVIE  LT N               +D+ A+++ ++  +  + +  LY KF+S +         +S D+ KF      R  +KH++D ++  L+   YK+  H QS+YSF+  N LD FG+++ ++A  Q LGYK++ L+LSEDHAW+ + G ++             TA+V W GK +E+KR   I  G  E+S LYL G  V+C+   + V++ ++ IN                  I T+  S EL  L+++LLW+ Y M  L+KYP+AL NL DLE   P +N   P        + L++EA   + +YYNN HVYPY  +  Y Y+  DY  AL  W  AA+VI KYNY  ED  IY+EF EIA   +P++ +    E+      +  ++H S                      L  + E  + FL F+D IC WEE S  PVLH  WA +    + +F  S R+ ++  G + +
Sbjct:    6 DREKQFFPLQNIQDVVKLFRDQLTCGE-----EPNLSLLSIVLGVIENILTVN---------RAIPTEVDNSANLEPIFPVVELHTIEALYSKFESHI--------KRSVDLTKFPGPHATRELVKHVSDVIWGSLTRSFYKDKAHLQSLYSFLTGNKLDCFGVAFGVVAAFQVLGYKDVHLALSEDHAWVVF-GENLAE-----------TAEVTWHGKGNEDKRGQPITAGTTEKSWLYLNGYPVICTR-EMEVSSIVSGINLA----------------ITTTMDSVELGSLQQELLWLLYDMGQLKKYPMALGNLGDLEEITPSENRKKP--------IELFQEAIASSQEYYNNQHVYPYTYLGGYLYRKQDYNGALQAWADAASVIKKYNYNREDEEIYKEFLEIANDLIPSMMKHVAGEN------AARIHHTS----------------------LLYNPESYANFLRFYDGICEWEEDSPTPVLHITWAKQLVFSISKFDISVRIGVDLKGENGD 442
[Close]
BLAST of menin vs. TrEMBL
Match: Q95P54 (Multiple endocrine neoplasia type 1 OS=Lymnaea stagnalis OX=6523 GN=MEN1 PE=2 SV=1)

HSP 1 Score: 278.485 bits (711), Expect = 1.273e-77
Identity = 178/511 (34.83%), Postives = 265/511 (51.86%), Query Frame = 2 
Query:   86 NKLKKYFPLTNINDILTLFESLLSMSKLENSYEPNIAFVSILLGVIEYKLTHNADDDENQCENVFINNIDDYASVKILYIT-FNDVIVLYKKFQSILWEMINCKSPKSEDVNKFLDRCTLKHITDAVYQKLSVGKYKENCHSQSIYSFIQDNSLDSFGLSYTILAITQQLGYKNIWLSLSEDHAWLEYEGNDINNNQSASSNSHKITADVAWSGKNHENKRCGSIDIGIIERSRLYLGGNSVVCSNNRITVAAAITTINPVKGSHSLSLNGYSNRNQIITSCHSSELAYLKRDLLWIAYKMNLLEKYPLALINLADLEMNYPKNTLNPNGNYFFGLLGLYREAADINLKYYNNSHVYPYLSMANYFYKDGDYQRALTCWRLAANVISKYNYKSEDWIIYREFFEIATHFVPNIFRLNNKEDDHHSKSSGSVYHASENESTKDRNRVSVDCKSLTCDELKNSVEFLSEFLCFFDFICLWEEGSSVPVLHEVWANKFKEVLCRFSESTRVELN 1615
            ++ KK+FPLT+I+ ++ LF+      +LE   EPN+A +SI+LG IE  LT N              N DD     I  +   + V  LY KF++++   ++     ++    F  R  +K I+D ++  LS   +K+  H QS+YSF+  N LD FG+++ ++A +Q LG  +I LSLSEDHAW+ + G D  +           TA+V W GK +E+KR  SI + + E+S LYL G+ V+C  N + VAA ++  NP       S+N  ++         S E+  L+++LLW+ Y    L KYP+ L NL DLE   P     P        L +++EA    +KYY+N HVYPY  M  Y Y+   Y+ A+ CW  A+NVI K+NY  ED  IY+EF EI+   +PNI +                   + + +T DR ++++         L N  E   + L F+D IC WEEGSS PVLH  WA      L +F   TR +++
Sbjct:    6 DRAKKHFPLTDISSVINLFKE-----QLEGPDEPNLALLSIVLGCIENTLTLN---------RAISTNEDDRLLRPIFPVVDLSTVDALYTKFETLVKGSVDL----TKYTGTFSSRELVKKISDVIWSSLSRS-FKDKAHLQSLYSFLTGNKLDCFGVAFGVVAASQLLGRNDIHLSLSEDHAWVVF-GEDGTD-----------TAEVTWHGKGNEDKRGQSIALSVAEKSWLYLNGHPVICDRN-MEVAALVSAANP-------SINMMTD---------SIEMGALQQELLWLLYDKGHLLKYPMGLGNLGDLEEISPNPGRPPP-------LAIFQEAISSAIKYYDNHHVYPYTYMGGYLYRKRRYKEAIKCWAEASNVIRKFNYTREDEEIYKEFLEISNELIPNIVK-------------------AVSLNTTDRVQMNI---------LYNP-EVYGDILRFYDGICEWEEGSSTPVLHVGWAQHLTFSLNKFDPRTRAKID 432
[Close]
BLAST of menin vs. TrEMBL
Match: A0A2C9JWR3 (Uncharacterized protein OS=Biomphalaria glabrata OX=6526 GN=106071077 PE=4 SV=1)

HSP 1 Score: 278.1 bits (710), Expect = 1.795e-77
Identity = 180/513 (35.09%), Postives = 270/513 (52.63%), Query Frame = 2 
Query:   86 NKLKKYFPLTNINDILTLFESLLSMSKLENSYEPNIAFVSILLGVIEYKLTHNADDDENQCENVFINNIDDYASVKILY--ITFNDVIVLYKKFQSILWEMIN-CKSPKSEDVNKFLDRCTLKHITDAVYQKLSVGKYKENCHSQSIYSFIQDNSLDSFGLSYTILAITQQLGYKNIWLSLSEDHAWLEYEGNDINNNQSASSNSHKITADVAWSGKNHENKRCGSIDIGIIERSRLYLGGNSVVCSNNRITVAAAITTINPVKGSHSLSLNGYSNRNQIITSCHSSELAYLKRDLLWIAYKMNLLEKYPLALINLADLEMNYPKNTLNPNGNYFFGLLGLYREAADINLKYYNNSHVYPYLSMANYFYKDGDYQRALTCWRLAANVISKYNYKSEDWIIYREFFEIATHFVPNIFRLNNKEDDHHSKSSGSVYHASENESTKDRNRVSVDCKSLTCDELKNSVEFLSEFLCFFDFICLWEEGSSVPVLHEVWANKFKEVLCRFSESTRVELN 1615
            +K+KK+FPLT+I  ++ LF+      +LE++ EPN+A +SI+LG IE  LT N     N          DD   ++ ++  + F+ V  LY +F++++   ++  K P       + +R  +K I+D ++  LS   +K+  H QS+YSF+  N LD FG+++ ++A  Q LG  +I LSLSEDHAW+ + G D  +           TA+V W GK +E+KR  SI + + E+S LYL G+ V+C N  I VAA ++  NP                 I  +  S E+  L+++LLW+ Y    L KYP+AL NL DLE   P     P        L +++EA    +K+Y+N HVYPY  M  Y Y+   Y+ A+ CW  A+NVI K+NY  ED  IY+EF EIA   +PNI +                   + + +T DR ++++         L N  E  ++ L F+D IC WEEGSS PVLH  WA      L +F   TR +++
Sbjct:    6 DKVKKHFPLTDIKSVINLFKE-----QLESNEEPNLALLSIVLGCIENTLTLNRAVPTN----------DDTKLLRPIFPIVDFSTVDALYTQFETLVKGSVDLTKYPSG-----YSNRDLVKKISDVIWSSLSRS-FKDKAHLQSLYSFLTGNKLDCFGVAFGVVAAAQLLGRNDIHLSLSEDHAWVIF-GEDGTD-----------TAEVTWHGKGNEDKRGQSIALSVAEKSWLYLNGHPVIC-NRMIEVAAIVSAANP----------------SINFTTDSIEMGALQQELLWLLYDKGHLSKYPMALGNLGDLEEISPTPGRPPP-------LCIFQEAITSAIKHYDNHHVYPYTYMGAYLYRKRCYKEAIKCWAEASNVIRKFNYTREDEEIYKEFLEIANELIPNIVK-------------------AVSLNTLDRAQMNI---------LYNP-EVYADILRFYDGICEWEEGSSTPVLHVGWAQHLTFSLNKFDPRTRAKID 432
[Close]
BLAST of menin vs. Ensembl Cavefish
Match: men1 (menin 1 [Source:NCBI gene;Acc:103032489])

HSP 1 Score: 232.646 bits (592), Expect = 1.234e-65
Identity = 163/516 (31.59%), Postives = 261/516 (50.58%), Query Frame = 2 
Query:   95 KKYFPLTNINDILTLFESLLSMSKLENSYEPNIAFVSILLGVIEYKLTHNADDDENQCENVFINNIDDYASVKILYITFNDVIVLYKKFQSILWEMINC---KSPKSEDVNKFLDRCTLKHITDAVYQKLSVGKYKENCHSQSIYSFIQDNSLDSFGLSYTILAITQQLGYKNIWLSLSEDHAWLEYEGNDINNNQSASSNSHKITADVAWSGKNHENKRCGSIDIGIIERSRLYLGGNSVVCSNNRITVAAAITTINPVKGSHSLSLNGYSNRNQIITSCHSSELAYLKRDLLWIAYKMNLLEKYPLALINLADLEMNYPKNTLNPNGNYFFGLLGLYREAADINLKYYNNSHVYPYLSMANYFYKDGDYQRALTCWRLAANVISKYNYKSEDWIIYREFFEIATHFVPNIFRLNNKEDDHHSKSSGSVYHASENESTKDRNRVSVDCKSLTCDELKNSVEFLSEFLCFFDFICLWEEGSSVPVLHEVWANKFKEVLCRFSESTRVELNTIGVDA 1633
            KK+FPL  I+ ++ LFE+ L+      + EP++A +S++LG +E+ L  N     N     F     D  +     +    +  L+++F + +   ++    + P          R  +K ++D ++  LS   +K+  H QS++S I    LDS G+++ ++A  Q LG K++ L+LSEDHAW+ +                + TA+V W GK +E++R  ++  G+ ERS LYL G+ + C+ N + VA  +  INP     SL L+             SSEL  L++ LLW+ Y+   LE+YP+++  LADLE   P   ++  G+     L ++ +A +   KYYNN H+YP++ +A Y Y+  + + AL  W  AA+V+  YNY  ED  IY+EFF+IA   +P +     KE    ++S G     +E    KD+ R +    +L         E  +  L F+D IC WEEGS  PVLH  WA    + L RF    R ++  I  +A
Sbjct:    8 KKHFPLRGIDGVVQLFEAELA------NPEPDLALLSLVLGFVEHFLAVNRVVPFNVPGVRFEPLKGDCLNSCFPTVELGLISALHERFTAQIRGAVDLSMYRKPAGGS-----SRELVKKVSDVIWNSLSRSYFKDRAHIQSLFSLITGTKLDSSGVAFAVVAACQVLGLKDVHLALSEDHAWVIF------------GKGGEETAEVTWHGKGNEDRRGQTVTAGVNERSWLYLKGSYMKCNRN-MEVAFMVCAINP-----SLDLH-----------TDSSELLQLQQRLLWLLYERGDLERYPMSMGTLADLEDQEP---MSGKGD----PLSIHLKAVESAKKYYNNEHIYPFMYLAGYHYRHRNVREALGAWAEAASVMQDYNYCREDEEIYKEFFDIANDVIPTLL----KETAGPAESGGEGTEGAE----KDQPRQAAAFSAL------QDPECFAHLLRFYDGICKWEEGSPTPVLHVGWATYLVQSLSRFDAQIRQKVAIITKEA 462
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BLAST of menin vs. Ensembl Sea Lamprey
Match: ENSPMAT00000003627.1 (pep scaffold:Pmarinus_7.0:GL479244:30682:34652:-1 gene:ENSPMAG00000003316.1 transcript:ENSPMAT00000003627.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 93.2041 bits (230), Expect = 6.937e-21
Identity = 59/172 (34.30%), Postives = 85/172 (49.42%), Query Frame = 2 
Query: 1106 EAADINLKYYNNSHVYPYLSMANYFYKDGDYQRALTCWRLAANVISKYNYKSEDWIIYREFFEIATHFVPNIFRLNNKEDDHHSKSSGSVYHASENESTKDRNRVSVDCKSLTCDELKNSVEFLSEFLCFFDFICLWEEGSSVPVLHEVWANKFKEVLCRFSESTRVELNTI 1621
            +A     K+Y N HVYPYL +A++  +    + AL  W  AA+V+  YNY  ED  IY+EFF+IA   +P++ +           +S      +E    KD   V    K+     L +   F +  L F+D IC WEEGS+ PVLH  WA    + + RF    R +L T+
Sbjct:    1 QAIGTAQKFYRNQHVYPYLYLASFHQRHRHLRSALQAWGEAASVVQTYNYNREDEEIYKEFFDIANDVIPSLLK---------EMASSEEEVEAEGSEGKD-GAVGAAGKATG---LHDPWAF-AHLLRFYDGICKWEEGSTTPVLHVGWATFLVQSVSRFDSKAR-QLVTV 157
[Close]
BLAST of menin vs. Ensembl Nematostella
Match: EDO43008 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RZU9])

HSP 1 Score: 194.897 bits (494), Expect = 2.217e-53
Identity = 156/514 (30.35%), Postives = 241/514 (46.89%), Query Frame = 2 
Query:  104 FPLTNINDILTLFESLLSMSKLENSYEPNIAFVSILLGVIEYKLTHNADDDENQCENVFINNIDDYASVKILYITFNDVIVLYKKFQSILWEMINCKS---PKSEDVNKFLDRCTLKHITDAVYQKLSVGKYKENCHSQSIYSFIQDNSLDSFGLSYTILAITQQLGYKNIWLSLSEDHAWLEYEGNDINNNQSASSNSHKITADVAWSGKNHENKRCGSIDIGIIER-SRLYLGGNSVVCSNNRITVAAAITTINPVKGSHSLSLNGYSNRNQIITSCHSSELAYLKRDLLWIAYKMNLLEKYPLALINLADLEMNYPKNTLNPNGNYFFGLLGLYREAADINLKYYNNSHVYPYLSMANYFYKDGDYQRALTCWRLAANVISKYNYKSEDWIIYREFFEIATHFVPNIFRLNNKEDDHHSKSSGSVYHASENESTKDRNRVSVDCKSLTCDELKNSVEFLSEFLCFFDFICLWEEGSSVPVLHEVWANKFKEVLCRFSESTRVELNTIGVDA 1633
            FPL +I  ++ +F       +L N  +PN+A +SI+LG  E   T  A D           ++D+         TF+    L+ KF ++L       +   P + ++        +K++ D V+  L+   +K+  H Q++YSF+  N LD FG+++ ++A+ Q LGY ++ L+LSEDHAW+ +  + I             TA+V W GK +E+KR   +     +R S LYL GN+V C+ + + VA+ I++INP             N N    S   S+L      L    Y M  ++ YP+A+ NL DLE   P     P          L++EA  +  + Y++ H+YPY  +  Y+Y+   Y  A+  W  A  V  KYNY  +D  +Y+EF EIA   +PNI +      D  +K+  S                     +LT D      +F +  L F+D ICLWEEGS  PVLH  WA K  + + +F+   R   N    DA
Sbjct:    8 FPLKDIKSVVEVFRQ-----ELRND-QPNLAQLSIVLGFFESASTMKAGD------TTSTPSLDEE--------TFD---ALHCKFMALLQRDFTFNAGGLPATREI--------VKNVADLVWGCLAKSYFKDRPHIQNLYSFLTGNRLDCFGVAFAVVAMCQALGYNDVHLALSEDHAWVVFGKDKIE------------TAEVTWHGKGNEDKRGKPVIYQDDDRCSWLYLNGNAVHCTRH-MEVASIISSINP-------------NINHTTDSIQLSQLQQELLWL---LYDMGHIKTYPMAIANLGDLEEISPTPGRPPAEE-------LFKEAITVAKREYSDHHIYPYTYLGGYYYRKKKYYEAIASWVDAGYVAGKYNYSKDDEEMYKEFHEIANDLIPNILK------DAVAKADPS----------------GTGSTNLTSDP-----KFFALVLQFYDGICLWEEGSPTPVLHADWAKKLVQSIGKFAPECRSAFNANTDDA 427
[Close]
BLAST of menin vs. Ensembl Medaka
Match: men1 (menin 1 [Source:NCBI gene;Acc:101155467])

HSP 1 Score: 221.476 bits (563), Expect = 3.473e-61
Identity = 163/509 (32.02%), Postives = 249/509 (48.92%), Query Frame = 2 
Query:   95 KKYFPLTNINDILTLFESLLSMSKLENSYEPNIAFVSILLGVIEYKLTHNADDDENQCENVFINNIDDYASVKILYITFNDVIVLYKKFQSILWEMINCKSPKSEDVNKFLDRCTLKHITDAVYQKLSVGKYKENCHSQSIYSFIQDNSLDSFGLSYTILAITQQLGYKNIWLSLSEDHAWLEYEGNDINNNQSASSNSHKITADVAWSGKNHENKRCGSIDIGIIERSRLYLGGNSVVCSNNRITVAAAITTINPVKGSHSLSLNGYSNRNQIITSCHSSELAYLKRDLLWIAYKMNLLEKYPLALINLADLEMNYPKNTLNPNGNYFFGLLGLYREAADINLKYYNNSHVYPYLSMANYFYKDGDYQRALTCWRLAANVISKYNYKSEDWIIYREFFEIATHFVPNIFRLNNKEDDHHSKSSGSVYHASENESTKDRNRVSVDCKSLTCDELKNSVEFLSEFLCFFDFICLWEEGSSVPVLHEVWANKFKEVLCRFSESTRVELNTI 1621
            KK FPL  I+ ++ LF++ L         EP++A +S++LG +E+ L  N     N     F     D  +     +    +  LY++F + +   ++    +         R  +K ++D ++  LS   +K+  H QS++S I    LDS G+++ ++A  Q LG K++ L+LSEDHAW+ + G D              TA+V W GK +E++R  ++  G+ E+S LYL G+ + C  N + VA  +  INP     SL L+             SSEL  L++ LLW+ Y+ N LE+YP+A+  LADLE   P   +   GN     L ++ +A     KYYNN H+YPY+ +A + Y+  D + AL  W  AA V+  YNY  ED  IY+EFF+IA   +P + +     D    +  G          T D+    V  K        +  E  +  L F+D IC WEEGS  PVLH  WA    + L RF    R +++ I
Sbjct:   74 KKLFPLRGIDGVVQLFDAEL------RKPEPDLALLSLVLGFVEHFLAVNRVVPINVPGVRFEPLEPDCPASCFPTVELGMISALYERFTAQIRGAVDLS--QYRRTASASSRELVKKVSDVIWNSLSRSYFKDRAHIQSLFSLITGTKLDSTGVAFAVVAACQVLGLKDVHLALSEDHAWVIF-GKDGEE-----------TAEVTWHGKGNEDRRGQTVTAGVNEKSWLYLKGSYMKCDRN-MEVAFMVCAINP-----SLDLH-----------TDSSELLQLQQKLLWLLYERNDLERYPMAMGTLADLEDQDP---IPGKGN----PLSIHLKAVQSAQKYYNNEHIYPYMYLAGFHYRHKDVREALKAWAAAAQVMQDYNYFREDEEIYKEFFDIANDVIPTLLKETAAADSIGEEDGG---------ETADK----VSTKQAAAFSALHDPECFAHLLRFYDGICKWEEGSPTPVLHVGWATYLVQSLSRFEAQVRQKVSII 525
[Close]
BLAST of menin vs. Planmine SMEST
Match: SMESG000028616.1 (SMESG000028616.1)

HSP 1 Score: 1647.48 bits (4265), Expect = 0.000e+0
Identity = 807/807 (100.00%), Postives = 807/807 (100.00%), Query Frame = 2 
Query:   74 MISVNKLKKYFPLTNINDILTLFESLLSMSKLENSYEPNIAFVSILLGVIEYKLTHNADDDENQCENVFINNIDDYASVKILYITFNDVIVLYKKFQSILWEMINCKSPKSEDVNKFLDRCTLKHITDAVYQKLSVGKYKENCHSQSIYSFIQDNSLDSFGLSYTILAITQQLGYKNIWLSLSEDHAWLEYEGNDINNNQSASSNSHKITADVAWSGKNHENKRCGSIDIGIIERSRLYLGGNSVVCSNNRITVAAAITTINPVKGSHSLSLNGYSNRNQIITSCHSSELAYLKRDLLWIAYKMNLLEKYPLALINLADLEMNYPKNTLNPNGNYFFGLLGLYREAADINLKYYNNSHVYPYLSMANYFYKDGDYQRALTCWRLAANVISKYNYKSEDWIIYREFFEIATHFVPNIFRLNNKEDDHHSKSSGSVYHASENESTKDRNRVSVDCKSLTCDELKNSVEFLSEFLCFFDFICLWEEGSSVPVLHEVWANKFKEVLCRFSESTRVELNTIGVDANILNEIQSIEEILFLPSNCSKPICQPKHDENESKPMSLVKSRQNSPNKSKRKPIKRLSLSNEELNQIKEFWIALCNNETKNLSTILSSKVLNLDFLLNFNSVKMFELSHILEPIDYENLNCENLCQLKTDKEFIDYFSTFKSVRDILNDNNDRNTSSSINSTQKNIESDQVLQELSNDQSHRCKYENSSNVPKIILESKSENEINQKSSYKIDSKSCQKIPLMDVFKSQKMKDICPLIVAPGKLNVPAIKLPLTAQSQVSLKRTGLHSVYGSFEFSNTMSRKRLKRE 2494
            MISVNKLKKYFPLTNINDILTLFESLLSMSKLENSYEPNIAFVSILLGVIEYKLTHNADDDENQCENVFINNIDDYASVKILYITFNDVIVLYKKFQSILWEMINCKSPKSEDVNKFLDRCTLKHITDAVYQKLSVGKYKENCHSQSIYSFIQDNSLDSFGLSYTILAITQQLGYKNIWLSLSEDHAWLEYEGNDINNNQSASSNSHKITADVAWSGKNHENKRCGSIDIGIIERSRLYLGGNSVVCSNNRITVAAAITTINPVKGSHSLSLNGYSNRNQIITSCHSSELAYLKRDLLWIAYKMNLLEKYPLALINLADLEMNYPKNTLNPNGNYFFGLLGLYREAADINLKYYNNSHVYPYLSMANYFYKDGDYQRALTCWRLAANVISKYNYKSEDWIIYREFFEIATHFVPNIFRLNNKEDDHHSKSSGSVYHASENESTKDRNRVSVDCKSLTCDELKNSVEFLSEFLCFFDFICLWEEGSSVPVLHEVWANKFKEVLCRFSESTRVELNTIGVDANILNEIQSIEEILFLPSNCSKPICQPKHDENESKPMSLVKSRQNSPNKSKRKPIKRLSLSNEELNQIKEFWIALCNNETKNLSTILSSKVLNLDFLLNFNSVKMFELSHILEPIDYENLNCENLCQLKTDKEFIDYFSTFKSVRDILNDNNDRNTSSSINSTQKNIESDQVLQELSNDQSHRCKYENSSNVPKIILESKSENEINQKSSYKIDSKSCQKIPLMDVFKSQKMKDICPLIVAPGKLNVPAIKLPLTAQSQVSLKRTGLHSVYGSFEFSNTMSRKRLKRE
Sbjct:    1 MISVNKLKKYFPLTNINDILTLFESLLSMSKLENSYEPNIAFVSILLGVIEYKLTHNADDDENQCENVFINNIDDYASVKILYITFNDVIVLYKKFQSILWEMINCKSPKSEDVNKFLDRCTLKHITDAVYQKLSVGKYKENCHSQSIYSFIQDNSLDSFGLSYTILAITQQLGYKNIWLSLSEDHAWLEYEGNDINNNQSASSNSHKITADVAWSGKNHENKRCGSIDIGIIERSRLYLGGNSVVCSNNRITVAAAITTINPVKGSHSLSLNGYSNRNQIITSCHSSELAYLKRDLLWIAYKMNLLEKYPLALINLADLEMNYPKNTLNPNGNYFFGLLGLYREAADINLKYYNNSHVYPYLSMANYFYKDGDYQRALTCWRLAANVISKYNYKSEDWIIYREFFEIATHFVPNIFRLNNKEDDHHSKSSGSVYHASENESTKDRNRVSVDCKSLTCDELKNSVEFLSEFLCFFDFICLWEEGSSVPVLHEVWANKFKEVLCRFSESTRVELNTIGVDANILNEIQSIEEILFLPSNCSKPICQPKHDENESKPMSLVKSRQNSPNKSKRKPIKRLSLSNEELNQIKEFWIALCNNETKNLSTILSSKVLNLDFLLNFNSVKMFELSHILEPIDYENLNCENLCQLKTDKEFIDYFSTFKSVRDILNDNNDRNTSSSINSTQKNIESDQVLQELSNDQSHRCKYENSSNVPKIILESKSENEINQKSSYKIDSKSCQKIPLMDVFKSQKMKDICPLIVAPGKLNVPAIKLPLTAQSQVSLKRTGLHSVYGSFEFSNTMSRKRLKRE 807
The following BLAST results are available for this feature:
BLAST of menin vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
MEN18.278e-6430.80menin 1 [Source:HGNC Symbol;Acc:HGNC:7010][more]
MEN18.278e-6430.80menin 1 [Source:HGNC Symbol;Acc:HGNC:7010][more]
MEN18.278e-6430.80menin 1 [Source:HGNC Symbol;Acc:HGNC:7010][more]
MEN18.278e-6430.80menin 1 [Source:HGNC Symbol;Acc:HGNC:7010][more]
MEN18.278e-6430.80menin 1 [Source:HGNC Symbol;Acc:HGNC:7010][more]
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BLAST of menin vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of menin vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 3
Match NameE-valueIdentityDescription
Mnn11.015e-5126.81gene:FBgn0031885 transcript:FBtr0079401[more]
Mnn11.015e-5126.81gene:FBgn0031885 transcript:FBtr0110978[more]
Mnn11.497e-4830.52gene:FBgn0031885 transcript:FBtr0079402[more]
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BLAST of menin vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 1
Match NameE-valueIdentityDescription
men11.264e-6832.05multiple endocrine neoplasia I [Source:ZFIN;Acc:ZD... [more]
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BLAST of menin vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 3
Match NameE-valueIdentityDescription
men11.013e-5528.60menin 1 [Source:NCBI gene;Acc:549115][more]
men14.731e-4831.05menin 1 [Source:NCBI gene;Acc:549115][more]
men16.518e-4032.80menin 1 [Source:NCBI gene;Acc:549115][more]
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BLAST of menin vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Men11.876e-6331.19multiple endocrine neoplasia 1 [Source:MGI Symbol;... [more]
Men11.876e-6331.19multiple endocrine neoplasia 1 [Source:MGI Symbol;... [more]
Men12.175e-6331.19multiple endocrine neoplasia 1 [Source:MGI Symbol;... [more]
Men12.175e-6331.19multiple endocrine neoplasia 1 [Source:MGI Symbol;... [more]
Men12.175e-6331.19multiple endocrine neoplasia 1 [Source:MGI Symbol;... [more]
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BLAST of menin vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q9WVR8|MEN1_RAT4.388e-6330.99Menin OS=Rattus norvegicus OX=10116 GN=Men1 PE=1 S... [more]
sp|Q0P5I0|MEN1_BOVIN7.552e-6330.80Menin OS=Bos taurus OX=9913 GN=MEN1 PE=2 SV=1[more]
sp|O88559|MEN1_MOUSE1.522e-6231.19Menin OS=Mus musculus OX=10090 GN=Men1 PE=1 SV=2[more]
sp|A2SXS5|MEN1_CANLF2.490e-6130.89Menin OS=Canis lupus familiaris OX=9615 GN=MEN1 PE... [more]
sp|O00255|MEN1_HUMAN9.654e-6130.69Menin OS=Homo sapiens OX=9606 GN=MEN1 PE=1 SV=4[more]
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BLAST of menin vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
L0HB440.000e+099.83Menin (Fragment) OS=Schmidtea mediterranea OX=7932... [more]
C3ZKP71.129e-8234.73Uncharacterized protein OS=Branchiostoma floridae ... [more]
K1P0F75.012e-7833.59Menin OS=Crassostrea gigas OX=29159 GN=CGI_1000223... [more]
Q95P541.273e-7734.83Multiple endocrine neoplasia type 1 OS=Lymnaea sta... [more]
A0A2C9JWR31.795e-7735.09Uncharacterized protein OS=Biomphalaria glabrata O... [more]
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BLAST of menin vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 1
Match NameE-valueIdentityDescription
men11.234e-6531.59menin 1 [Source:NCBI gene;Acc:103032489][more]
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BLAST of menin vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 1
Match NameE-valueIdentityDescription
ENSPMAT00000003627.16.937e-2134.30pep scaffold:Pmarinus_7.0:GL479244:30682:34652:-1 ... [more]
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BLAST of menin vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of menin vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 1
Match NameE-valueIdentityDescription
EDO430082.217e-5330.35Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of menin vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 1
Match NameE-valueIdentityDescription
men13.473e-6132.02menin 1 [Source:NCBI gene;Acc:101155467][more]
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BLAST of menin vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 1
Match NameE-valueIdentityDescription
SMESG000028616.10.000e+0100.00SMESG000028616.1[more]
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Cross References
External references for this transcript
DatabaseAccession
SmedGD GBrowseSMED30028101
GenBankAGA95403.1
Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30028101 ID=SMED30028101|Name=menin|organism=Schmidtea mediterranea sexual|type=transcript|length=2711bp
TTAAAGATTTACGATTCATTTTTCGATTTATGTAATTGTCAAACCAGTTG
TTGCCATTTTACTATATTTTTCCATGATTTCTGTAAATAAATTAAAAAAA
TATTTTCCGTTAACTAATATAAATGATATATTAACACTTTTTGAAAGTCT
TCTTTCAATGTCTAAATTGGAAAACAGTTATGAACCAAATATTGCTTTTG
TATCCATTTTATTGGGTGTCATTGAATATAAATTGACTCATAATGCAGAT
GATGATGAAAATCAATGTGAAAACGTTTTTATAAATAATATTGATGATTA
TGCTTCTGTTAAAATTTTGTATATAACTTTCAATGATGTAATAGTTTTGT
ACAAAAAGTTTCAAAGTATATTATGGGAAATGATAAATTGTAAATCTCCA
AAGTCAGAAGATGTGAATAAATTTTTGGACAGATGCACTTTAAAACACAT
TACTGATGCTGTTTATCAAAAGCTTAGTGTTGGTAAGTACAAAGAGAATT
GTCATAGTCAAAGCATTTATTCATTTATTCAAGACAATTCTTTAGATAGT
TTCGGATTGTCATATACAATTTTAGCAATAACGCAGCAGTTGGGTTATAA
AAATATATGGTTGTCATTGTCAGAGGACCACGCCTGGTTAGAATATGAAG
GAAATGACATAAATAACAATCAGAGCGCTTCGAGTAATTCTCATAAAATA
ACTGCCGATGTAGCTTGGAGTGGAAAAAATCATGAAAACAAACGCTGTGG
ATCCATTGACATTGGAATCATTGAAAGATCTCGACTTTATCTTGGAGGAA
ATTCTGTCGTATGTAGCAATAATCGAATAACCGTTGCAGCAGCAATAACA
ACGATAAATCCAGTTAAAGGCAGTCATAGTTTATCATTGAATGGCTACAG
TAATCGCAATCAAATAATTACGTCTTGTCACAGTTCTGAATTGGCTTATC
TAAAAAGAGATTTATTATGGATAGCTTATAAGATGAATTTATTAGAAAAG
TATCCTCTTGCTTTGATCAATTTAGCAGATCTCGAAATGAATTATCCAAA
AAATACTTTAAATCCAAATGGAAATTATTTTTTCGGTCTCCTTGGACTTT
ATCGAGAAGCGGCAGACATAAATTTAAAATACTATAACAACAGCCATGTA
TATCCATATTTATCCATGGCAAATTATTTTTACAAAGATGGGGATTACCA
AAGAGCGTTGACATGCTGGAGATTGGCTGCAAATGTCATTAGCAAATACA
ATTATAAATCGGAAGATTGGATTATTTATCGAGAATTTTTCGAAATCGCA
ACTCATTTTGTTCCAAATATCTTTAGATTGAACAACAAAGAAGACGATCA
CCATTCCAAATCCAGTGGTTCTGTTTATCACGCCTCAGAAAACGAGTCAA
CAAAAGACCGTAATAGGGTGTCAGTTGACTGTAAATCATTAACTTGTGAT
GAGTTAAAAAATAGTGTCGAATTTCTAAGTGAATTCCTGTGCTTTTTTGA
TTTTATATGCTTATGGGAAGAAGGATCAAGTGTACCTGTGTTACATGAAG
TATGGGCCAACAAATTTAAAGAGGTTCTCTGTAGATTTTCAGAAAGTACT
AGAGTTGAACTTAATACTATCGGCGTTGATGCAAATATTTTGAATGAAAT
TCAGAGTATAGAGGAAATCTTGTTTCTACCAAGTAATTGTTCAAAGCCAA
TTTGTCAACCAAAGCATGATGAAAATGAATCGAAACCAATGTCACTTGTC
AAAAGTCGACAAAATTCTCCAAATAAGTCTAAACGTAAACCTATTAAAAG
ATTGTCACTATCTAATGAAGAATTAAATCAAATAAAAGAATTTTGGATAG
CTCTTTGTAACAATGAAACGAAAAATCTCTCAACTATTCTCTCTTCCAAA
GTATTAAATCTCGATTTTCTACTAAATTTTAATTCAGTGAAAATGTTTGA
ATTAAGTCATATTCTTGAACCCATCGATTATGAAAATCTCAATTGTGAAA
ATCTTTGTCAGTTAAAAACAGATAAAGAATTTATTGATTATTTTTCTACG
TTTAAAAGCGTTCGCGATATTCTCAATGACAATAATGATCGAAACACGAG
TAGTAGTATTAATTCAACTCAAAAGAATATTGAATCAGACCAAGTTTTAC
AAGAATTATCCAATGATCAATCTCATCGCTGTAAATATGAAAATTCTTCC
AATGTACCAAAAATAATTTTGGAATCTAAATCCGAAAATGAGATAAATCA
AAAATCATCATATAAAATTGACAGTAAAAGTTGTCAAAAAATACCATTGA
TGGATGTCTTCAAGTCACAAAAGATGAAGGATATTTGTCCTTTGATTGTT
GCACCGGGAAAGTTGAACGTTCCTGCCATTAAGCTACCGTTAACTGCACA
AAGTCAGGTATCTTTGAAAAGGACAGGATTGCATTCAGTTTATGGGAGTT
TTGAATTTTCAAATACCATGTCAAGAAAAAGACTTAAACGGGAGTAATTG
TGTTTGACAGTTGTAATTGACAATTTTAATTGACATCATGATTCATTCCA
AATTCTCCTTTATCTATCATAATCATTTCATACATATATTTATATTGCTC
ATATTGCAATACTGAATGATTGATTTATATAATTAGTGGCCTTACTGTTC
TTTTTCCCGGTAGATTCTCTCTTCAATTCATATTGTTGCATTTATAAATT
TGTATTTTAAA
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protein sequence of SMED30028101-orf-1

>SMED30028101-orf-1 ID=SMED30028101-orf-1|Name=SMED30028101-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=808bp
MISVNKLKKYFPLTNINDILTLFESLLSMSKLENSYEPNIAFVSILLGVI
EYKLTHNADDDENQCENVFINNIDDYASVKILYITFNDVIVLYKKFQSIL
WEMINCKSPKSEDVNKFLDRCTLKHITDAVYQKLSVGKYKENCHSQSIYS
FIQDNSLDSFGLSYTILAITQQLGYKNIWLSLSEDHAWLEYEGNDINNNQ
SASSNSHKITADVAWSGKNHENKRCGSIDIGIIERSRLYLGGNSVVCSNN
RITVAAAITTINPVKGSHSLSLNGYSNRNQIITSCHSSELAYLKRDLLWI
AYKMNLLEKYPLALINLADLEMNYPKNTLNPNGNYFFGLLGLYREAADIN
LKYYNNSHVYPYLSMANYFYKDGDYQRALTCWRLAANVISKYNYKSEDWI
IYREFFEIATHFVPNIFRLNNKEDDHHSKSSGSVYHASENESTKDRNRVS
VDCKSLTCDELKNSVEFLSEFLCFFDFICLWEEGSSVPVLHEVWANKFKE
VLCRFSESTRVELNTIGVDANILNEIQSIEEILFLPSNCSKPICQPKHDE
NESKPMSLVKSRQNSPNKSKRKPIKRLSLSNEELNQIKEFWIALCNNETK
NLSTILSSKVLNLDFLLNFNSVKMFELSHILEPIDYENLNCENLCQLKTD
KEFIDYFSTFKSVRDILNDNNDRNTSSSINSTQKNIESDQVLQELSNDQS
HRCKYENSSNVPKIILESKSENEINQKSSYKIDSKSCQKIPLMDVFKSQK
MKDICPLIVAPGKLNVPAIKLPLTAQSQVSLKRTGLHSVYGSFEFSNTMS
RKRLKRE*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000044cephalic ganglia
Vocabulary: INTERPRO
TermDefinition
IPR007747Menin
Vocabulary: cellular component
TermDefinition
GO:0005634nucleus
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR007747MeninPFAMPF05053Menincoord: 10..787
e-value: 2.3E-95
score: 320.4
IPR007747MeninPANTHERPTHR12693FAMILY NOT NAMEDcoord: 5..594
coord: 679..793
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 548..573