Phosphodiesterase

Overview


Name	Phosphodiesterase
Smed ID	SMED30028097
Length (bp)	3069

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of Phosphodiesterase (SMED30028097) t-SNE clustered cells

Violin plots show distribution of expression levels for Phosphodiesterase (SMED30028097) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Phosphodiesterase (SMED30028097) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Phosphodiesterase (SMED30028097) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30028097

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 9

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication
nervous system	SMED30028097	SMESG000051078.1	dd_Smed_v4_6976_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
epidermis	SMED30028097	SMESG000051078.1	dd_Smed_v4_6976_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
cephalic ganglia	SMED30028097	SMESG000051078.1	dd_Smed_v4_6976_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
neuron	SMED30028097	SMESG000051078.1	dd_Smed_v4_6976_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
muscle cell	SMED30028097	SMESG000051078.1	dd_Smed_v4_6976_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
non-ciliated neuron	SMED30028097	SMESG000051078.1	dd_Smed_v4_6976_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30028097	SMESG000051078.1	Contig49257	newmark_ests	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30028097	SMESG000051078.1	Contig49257	uc_Smed_v2	PMID:29674431 Fincher et al., 2018
epidermis	SMED30028097	SMESG000051078.1	dd_Smed_v4_6976_0_1	dd_Smed_v4	PMID:28292427 Wurtzel et al., 2017

Note: Hover over icons to view figure legend

Homology

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BLAST of Phosphodiesterase vs. Ensembl Human
Match: PDE2A (phosphodiesterase 2A [Source:HGNC Symbol;Acc:HGNC:8777])

HSP 1 Score: 770.77 bits (1989), Expect = 0.000e+0
Identity = 395/864 (45.72%), Postives = 567/864 (65.62%), Query Frame = 1

Query:  295 RELLLGLSNIVSYEEIPDAVKTTINRVFPNSNSVRLEWINTR-----ENSTKSIRSNGWMNENKIIPQSSLIINR---KDRLQEQYSDYFDSENSDNFGIIVPLISSEMKEFQAFLSFSCQEFNQNEKKLLQTFEN-------QVKVMFQRLERLKNSKDSNLQQSNLQDTKLDSSDFYIDSTILSLCADLHDRDPGILQVKIIRFLKQRIHMESAFILTISNNNLELVCQAQDEQIFDPEKRFRVTDSIFERIMKEKICAQLSDVNMFQDKLNELELLTNIKWNSFLCVPIINQSDGCVSALVCMINKIGSNQSFTAEDISITQHLFQYTAAVLTSSVAFQMERRLKIQTETMLQVAMNIFRKLGDLTGLLKEIMTEAKKLTNAERCSVFLVDNDTKELVSKVFDGLPTISEQSQHPVEIRIPVTQGVAGRVATTGEMLNIVDAYSHPLFYRGVDEETGYKTRNILCFPIKDENEKVVGVAQLCNKINGPCFTNYDEDIAKAFSVYCCISIMHSLMYKKVQDAQHRNKLANELMIYHMQVNEDTVKWLTSCGYPDLMDIKEDFNSFECIPRDIKEHDSALAVLGMFNTLGFISKWRLSRPTLSRFILMIKRGYRDPPYHNWTHAFSVAHFIYLCITNLPLHGQLLPIELLALFVASLCHDIDHRGTNNSFQVTSKSVLAALYSSEGSVLERHHFSQTICVLNSEGCNIFENFSRQDYHHVLDLIRDIILATDLAHHLRIISDQRKMIDTFYDSNSNHHHVLLMDLLMTSADLSDQSKNWKNTRAVAQLIYEEFFSQGDMEKSIGQKPAEQMDRERACVPSLQMSFLDGIALPCFQLFADLYPLFGQKMIENITNNRKKWEKLN 2841
            ++ LL L +++    +  AVK  ++ V P   +V    ++       E+    +   G + E  II Q  L  N     D   +  +        D   +++PL   E     A +   C + + NE+  LQ  E        +V+V+ QR  R       N  +   +D K  ++    D  IL LC +L+D D   LQ+K++++L+Q        +L +S +NL+L C+   +++   E  F +T  + + ++++K   QL D+    + + +L+ +   +  + LCVP+I+++   V AL C  NK+  +  FT ED  + QH F YT+ VLTS++AFQ E++LK + + +LQVA N+F  L D++ LL+EI+TEA+ L+NAE CSVFL+D +  ELV+KVFDG   + ++S    EIRIP  QG+AG VATTG++LNI DAY+HPLFYRGVD+ TG++TRNILCFPIK+EN++V+GVA+L NKINGP F+ +DED+A AFS+YC ISI HSL+YKKV +AQ+R+ LANE+M+YHM+V++D    L   G   +  I  +F SF   PR + E D+++A+L M   + FI+ +++  PTL+RF LM+K+GYRDPPYHNW HAFSV+HF YL   NL L   L  IE+ ALF++ +CHD+DHRGTNNSFQV SKSVLAALYSSEGSV+ERHHF+Q I +LN+ GCNIF++FSR+DY  +LDL+RDIILATDLAHHLRI  D +KM +  YD N+  HH LL+ LLMTS DLSDQ+K WK TR +A+LIY+EFFSQGD+EK++G +P E MDRE+A +P LQ+SF++ IA+P ++L  DL+P    ++ E + +NR+ W K++
Sbjct:   39 QDALLSLGSVIDISGLQRAVKEALSAVLPRVETVYTYLLDGESQLVCEDPPHELPQEGKVRE-AIISQKRLGCNGLGFSDLPGKPLARLVAPLAPDTQVLVMPLADKEAGAVAAVILVHCGQLSDNEEWSLQAVEKHTLVALRRVQVLQQRGPREAPRAVQNPPEGTAEDQKGGAAYTDRDRKILQLCGELYDLDASSLQLKVLQYLQQETRASRCCLLLVSEDNLQLSCKVIGDKVLGEEVSFPLTGCLGQ-VVEDKKSIQLKDLT--SEDVQQLQSMLGCELQAMLCVPVISRATDQVVALACAFNKLEGDL-FTDEDEHVIQHCFHYTSTVLTSTLAFQKEQKLKCECQALLQVAKNLFTHLDDVSVLLQEIITEARNLSNAEICSVFLLDQN--ELVAKVFDG-GVVDDES---YEIRIPADQGIAGHVATTGQILNIPDAYAHPLFYRGVDDSTGFRTRNILCFPIKNENQEVIGVAELVNKINGPWFSKFDEDLATAFSIYCGISIAHSLLYKKVNEAQYRSHLANEMMMYHMKVSDDEYTKLLHDGIQPVAAIDSNFASFTYTPRSLPEDDTSMAILSMLQDMNFINNYKIDCPTLARFCLMVKKGYRDPPYHNWMHAFSVSHFCYLLYKNLELTNYLEDIEIFALFISCMCHDLDHRGTNNSFQVASKSVLAALYSSEGSVMERHHFAQAIAILNTHGCNIFDHFSRKDYQRMLDLMRDIILATDLAHHLRIFKDLQKMAEVGYDRNNKQHHRLLLCLLMTSCDLSDQTKGWKTTRKIAELIYKEFFSQGDLEKAMGNRPMEMMDREKAYIPELQISFMEHIAMPIYKLLQDLFPK-AAELYERVASNREHWTKVS 890

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Query:  295 RELLLGLSNIVSYEEIPDAVKTTINRVFPNSNSVRLEWINTR-----ENSTKSIRSNGWMNENKIIPQSSLIINR---KDRLQEQYSDYFDSENSDNFGIIVPLISSEMKEFQAFLSFSCQEFNQNEKKLLQTFEN-------QVKVMFQRLERLKNSKDSNLQQSNLQDTKLDSSDFYIDSTILSLCADLHDRDPGILQVKIIRFLKQRIHMESAFILTISNNNLELVCQAQDEQIFDPEKRFRVTDSIFERIMKEKICAQLSDVNMFQDKLNELELLTNIKWNSFLCVPIINQSDGCVSALVCMINKIGSNQSFTAEDISITQHLFQYTAAVLTSSVAFQMERRLKIQTETMLQVAMNIFRKLGDLTGLLKEIMTEAKKLTNAERCSVFLVDNDTKELVSKVFDGLPTISEQSQHPVEIRIPVTQGVAGRVATTGEMLNIVDAYSHPLFYRGVDEETGYKTRNILCFPIKDENEKVVGVAQLCNKINGPCFTNYDEDIAKAFSVYCCISIMHSLMYKKVQDAQHRNKLANELMIYHMQVNEDTVKWLTSCGYPDLMDIKEDFNSFECIPRDIKEHDSALAVLGMFNTLGFISKWRLSRPTLSRFILMIKRGYRDPPYHNWTHAFSVAHFIYLCITNLPLHGQLLPIELLALFVASLCHDIDHRGTNNSFQVTSKSVLAALYSSEGSVLERHHFSQTICVLNSEGCNIFENFSRQDYHHVLDLIRDIILATDLAHHLRIISDQRKMIDTFYDSNSNHHHVLLMDLLMTSADLSDQSKNWKNTRAVAQLIYEEFFSQGDMEKSIGQKPAEQMDRERACVPSLQMSFLDGIALPCFQLFADLYPLFGQKMIENITNNRKKWEKLN 2841
            ++ LL L +++    +  AVK  ++ V P   +V    ++       E+    +   G + E  II Q  L  N     D   +  +        D   +++PL   E     A +   C + + NE+  LQ  E        +V+V+ QR  R       N  +   +D K  ++    D  IL LC +L+D D   LQ+K++++L+Q        +L +S +NL+L C+   +++   E  F +T     +++++K   QL D+    + + +L+ +   +  + LCVP+I+++   V AL C  NK+  +  FT ED  + QH F YT+ VLTS++AFQ E++LK + + +LQVA N+F  L D++ LL+EI+TEA+ L+NAE CSVFL+D +  ELV+KVFDG   + ++S    EIRIP  QG+AG VATTG++LNI DAY+HPLFYRGVD+ TG++TRNILCFPIK+EN++V+GVA+L NKINGP F+ +DED+A AFS+YC ISI HSL+YKKV +AQ+R+ LANE+M+YHM+V++D    L   G   +  I  +F SF   PR + E D+++A+L M   + FI+ +++  PTL+RF LM+K+GYRDPPYHNW HAFSV+HF YL   NL L   L  IE+ ALF++ +CHD+DHRGTNNSFQV SKSVLAALYSSEGSV+ERHHF+Q I +LN+ GCNIF++FSR+DY  +LDL+RDIILATDLAHHLRI  D +KM +  YD N+  HH LL+ LLMTS DLSDQ+K WK TR +A+LIY+EFFSQGD+EK++G +P E MDRE+A +P LQ+SF++ IA+P ++L  DL+P    ++ E + +NR+ W K++
Sbjct:   41 QDALLSLGSVIDISGLQRAVKEALSAVLPRVETVYTYLLDGESQLVCEDPPHELPQEGKVRE-AIISQKRLGCNGLGFSDLPGKPLARLVAPLAPDTQVLVMPLADKEAGAVAAVILVHCGQLSDNEEWSLQAVEKHTLVALRRVQVLQQRGPREAPRAVQNPPEGTAEDQKGGAAYTDRDRKILQLCGELYDLDASSLQLKVLQYLQQETRASRCCLLLVSEDNLQLSCKVIGDKVLGEEVSFPLT-GCLGQVVEDKKSIQLKDLT--SEDVQQLQSMLGCELQAMLCVPVISRATDQVVALACAFNKLEGDL-FTDEDEHVIQHCFHYTSTVLTSTLAFQKEQKLKCECQALLQVAKNLFTHLDDVSVLLQEIITEARNLSNAEICSVFLLDQN--ELVAKVFDG-GVVDDES---YEIRIPADQGIAGHVATTGQILNIPDAYAHPLFYRGVDDSTGFRTRNILCFPIKNENQEVIGVAELVNKINGPWFSKFDEDLATAFSIYCGISIAHSLLYKKVNEAQYRSHLANEMMMYHMKVSDDEYTKLLHDGIQPVAAIDSNFASFTYTPRSLPEDDTSMAILSMLQDMNFINNYKIDCPTLARFCLMVKKGYRDPPYHNWMHAFSVSHFCYLLYKNLELTNYLEDIEIFALFISCMCHDLDHRGTNNSFQVASKSVLAALYSSEGSVMERHHFAQAIAILNTHGCNIFDHFSRKDYQRMLDLMRDIILATDLAHHLRIFKDLQKMAEVGYDRNNKQHHRLLLCLLMTSCDLSDQTKGWKTTRKIAELIYKEFFSQGDLEKAMGNRPMEMMDREKAYIPELQISFMEHIAMPIYKLLQDLFPK-AAELYERVASNREHWTKVS 892

[Close]

BLAST of Phosphodiesterase vs. Ensembl Human
Match: PDE2A (phosphodiesterase 2A [Source:HGNC Symbol;Acc:HGNC:8777])

HSP 1 Score: 770.385 bits (1988), Expect = 0.000e+0
Identity = 395/861 (45.88%), Postives = 564/861 (65.51%), Query Frame = 1

Query:  304 LLGLSNIVSYEEIPDAVKTTINRVFPNSNSVRLEWINTR-----ENSTKSIRSNGWMNENKIIPQSSLIINR---KDRLQEQYSDYFDSENSDNFGIIVPLISSEMKEFQAFLSFSCQEFNQNEKKLLQTFEN-------QVKVMFQRLERLKNSKDSNLQQSNLQDTKLDSSDFYIDSTILSLCADLHDRDPGILQVKIIRFLKQRIHMESAFILTISNNNLELVCQAQDEQIFDPEKRFRVTDSIFERIMKEKICAQLSDVNMFQDKLNELELLTNIKWNSFLCVPIINQSDGCVSALVCMINKIGSNQSFTAEDISITQHLFQYTAAVLTSSVAFQMERRLKIQTETMLQVAMNIFRKLGDLTGLLKEIMTEAKKLTNAERCSVFLVDNDTKELVSKVFDGLPTISEQSQHPVEIRIPVTQGVAGRVATTGEMLNIVDAYSHPLFYRGVDEETGYKTRNILCFPIKDENEKVVGVAQLCNKINGPCFTNYDEDIAKAFSVYCCISIMHSLMYKKVQDAQHRNKLANELMIYHMQVNEDTVKWLTSCGYPDLMDIKEDFNSFECIPRDIKEHDSALAVLGMFNTLGFISKWRLSRPTLSRFILMIKRGYRDPPYHNWTHAFSVAHFIYLCITNLPLHGQLLPIELLALFVASLCHDIDHRGTNNSFQVTSKSVLAALYSSEGSVLERHHFSQTICVLNSEGCNIFENFSRQDYHHVLDLIRDIILATDLAHHLRIISDQRKMIDTFYDSNSNHHHVLLMDLLMTSADLSDQSKNWKNTRAVAQLIYEEFFSQGDMEKSIGQKPAEQMDRERACVPSLQMSFLDGIALPCFQLFADLYPLFGQKMIENITNNRKKWEKLN 2841
            LL L +++    +  AVK  ++ V P   +V    ++       E+    +   G + E  II Q  L  N     D   +  +        D   +++PL   E     A +   C + + NE+  LQ  E        +V+V+ QR  R       N  +   +D K  ++    D  IL LC +L+D D   LQ+K++++L+Q        +L +S +NL+L C+   +++   E  F +T     +++++K   QL D+    + + +L+ +   +  + LCVP+I+++   V AL C  NK+  +  FT ED  + QH F YT+ VLTS++AFQ E++LK + + +LQVA N+F  L D++ LL+EI+TEA+ L+NAE CSVFL+D +  ELV+KVFDG   + ++S    EIRIP  QG+AG VATTG++LNI DAY+HPLFYRGVD+ TG++TRNILCFPIK+EN++V+GVA+L NKINGP F+ +DED+A AFS+YC ISI HSL+YKKV +AQ+R+ LANE+M+YHM+V++D    L   G   +  I  +F SF   PR + E D+++A+L M   + FI+ +++  PTL+RF LM+K+GYRDPPYHNW HAFSV+HF YL   NL L   L  IE+ ALF++ +CHD+DHRGTNNSFQV SKSVLAALYSSEGSV+ERHHF+Q I +LN+ GCNIF++FSR+DY  +LDL+RDIILATDLAHHLRI  D +KM +  YD N+  HH LL+ LLMTS DLSDQ+K WK TR +A+LIY+EFFSQGD+EK++G +P E MDRE+A +P LQ+SF++ IA+P ++L  DL+P    ++ E + +NR+ W K++
Sbjct:   30 LLSLGSVIDISGLQRAVKEALSAVLPRVETVYTYLLDGESQLVCEDPPHELPQEGKVRE-AIISQKRLGCNGLGFSDLPGKPLARLVAPLAPDTQVLVMPLADKEAGAVAAVILVHCGQLSDNEEWSLQAVEKHTLVALRRVQVLQQRGPREAPRAVQNPPEGTAEDQKGGAAYTDRDRKILQLCGELYDLDASSLQLKVLQYLQQETRASRCCLLLVSEDNLQLSCKVIGDKVLGEEVSFPLT-GCLGQVVEDKKSIQLKDLT--SEDVQQLQSMLGCELQAMLCVPVISRATDQVVALACAFNKLEGDL-FTDEDEHVIQHCFHYTSTVLTSTLAFQKEQKLKCECQALLQVAKNLFTHLDDVSVLLQEIITEARNLSNAEICSVFLLDQN--ELVAKVFDG-GVVDDES---YEIRIPADQGIAGHVATTGQILNIPDAYAHPLFYRGVDDSTGFRTRNILCFPIKNENQEVIGVAELVNKINGPWFSKFDEDLATAFSIYCGISIAHSLLYKKVNEAQYRSHLANEMMMYHMKVSDDEYTKLLHDGIQPVAAIDSNFASFTYTPRSLPEDDTSMAILSMLQDMNFINNYKIDCPTLARFCLMVKKGYRDPPYHNWMHAFSVSHFCYLLYKNLELTNYLEDIEIFALFISCMCHDLDHRGTNNSFQVASKSVLAALYSSEGSVMERHHFAQAIAILNTHGCNIFDHFSRKDYQRMLDLMRDIILATDLAHHLRIFKDLQKMAEVGYDRNNKQHHRLLLCLLMTSCDLSDQTKGWKTTRKIAELIYKEFFSQGDLEKAMGNRPMEMMDREKAYIPELQISFMEHIAMPIYKLLQDLFPK-AAELYERVASNREHWTKVS 878

[Close]

BLAST of Phosphodiesterase vs. Ensembl Human
Match: PDE2A (phosphodiesterase 2A [Source:HGNC Symbol;Acc:HGNC:8777])

HSP 1 Score: 770.385 bits (1988), Expect = 0.000e+0
Identity = 395/864 (45.72%), Postives = 567/864 (65.62%), Query Frame = 1

Query:  295 RELLLGLSNIVSYEEIPDAVKTTINRVFPNSNSVRLEWINTR-----ENSTKSIRSNGWMNENKIIPQSSLIINR---KDRLQEQYSDYFDSENSDNFGIIVPLISSEMKEFQAFLSFSCQEFNQNEKKLLQTFEN-------QVKVMFQRLERLKNSKDSNLQQSNLQDTKLDSSDFYIDSTILSLCADLHDRDPGILQVKIIRFLKQRIHMESAFILTISNNNLELVCQAQDEQIFDPEKRFRVTDSIFERIMKEKICAQLSDVNMFQDKLNELELLTNIKWNSFLCVPIINQSDGCVSALVCMINKIGSNQSFTAEDISITQHLFQYTAAVLTSSVAFQMERRLKIQTETMLQVAMNIFRKLGDLTGLLKEIMTEAKKLTNAERCSVFLVDNDTKELVSKVFDGLPTISEQSQHPVEIRIPVTQGVAGRVATTGEMLNIVDAYSHPLFYRGVDEETGYKTRNILCFPIKDENEKVVGVAQLCNKINGPCFTNYDEDIAKAFSVYCCISIMHSLMYKKVQDAQHRNKLANELMIYHMQVNEDTVKWLTSCGYPDLMDIKEDFNSFECIPRDIKEHDSALAVLGMFNTLGFISKWRLSRPTLSRFILMIKRGYRDPPYHNWTHAFSVAHFIYLCITNLPLHGQLLPIELLALFVASLCHDIDHRGTNNSFQVTSKSVLAALYSSEGSVLERHHFSQTICVLNSEGCNIFENFSRQDYHHVLDLIRDIILATDLAHHLRIISDQRKMIDTFYDSNSNHHHVLLMDLLMTSADLSDQSKNWKNTRAVAQLIYEEFFSQGDMEKSIGQKPAEQMDRERACVPSLQMSFLDGIALPCFQLFADLYPLFGQKMIENITNNRKKWEKLN 2841
            ++ LL L +++    +  AVK  ++ V P   +V    ++       E+    +   G + E  II Q  L  N     D   +  +        D   +++PL   E     A +   C + + NE+  LQ  E        +V+V+ QR  R       N  +   +D K  ++    D  IL LC +L+D D   LQ+K++++L+Q        +L +S +NL+L C+   +++   E  F +T  + + ++++K   QL D+    + + +L+ +   +  + LCVP+I+++   V AL C  NK+  +  FT ED  + QH F YT+ VLTS++AFQ E++LK + + +LQVA N+F  L D++ LL+EI+TEA+ L+NAE CSVFL+D +  ELV+KVFDG   + ++S    EIRIP  QG+AG VATTG++LNI DAY+HPLFYRGVD+ TG++TRNILCFPIK+EN++V+GVA+L NKINGP F+ +DED+A AFS+YC ISI HSL+YKKV +AQ+R+ LANE+M+YHM+V++D    L   G   +  I  +F SF   PR + E D+++A+L M   + FI+ +++  PTL+RF LM+K+GYRDPPYHNW HAFSV+HF YL   NL L   L  IE+ ALF++ +CHD+DHRGTNNSFQV SKSVLAALYSSEGSV+ERHHF+Q I +LN+ GCNIF++FSR+DY  +LDL+RDIILATDLAHHLRI  D +KM +  YD N+  HH LL+ LLMTS DLSDQ+K WK TR +A+LIY+EFFSQGD+EK++G +P E MDRE+A +P LQ+SF++ IA+P ++L  DL+P    ++ E + +NR+ W K++
Sbjct:   48 QDALLSLGSVIDISGLQRAVKEALSAVLPRVETVYTYLLDGESQLVCEDPPHELPQEGKVRE-AIISQKRLGCNGLGFSDLPGKPLARLVAPLAPDTQVLVMPLADKEAGAVAAVILVHCGQLSDNEEWSLQAVEKHTLVALRRVQVLQQRGPREAPRAVQNPPEGTAEDQKGGAAYTDRDRKILQLCGELYDLDASSLQLKVLQYLQQETRASRCCLLLVSEDNLQLSCKVIGDKVLGEEVSFPLTGCLGQ-VVEDKKSIQLKDLT--SEDVQQLQSMLGCELQAMLCVPVISRATDQVVALACAFNKLEGDL-FTDEDEHVIQHCFHYTSTVLTSTLAFQKEQKLKCECQALLQVAKNLFTHLDDVSVLLQEIITEARNLSNAEICSVFLLDQN--ELVAKVFDG-GVVDDES---YEIRIPADQGIAGHVATTGQILNIPDAYAHPLFYRGVDDSTGFRTRNILCFPIKNENQEVIGVAELVNKINGPWFSKFDEDLATAFSIYCGISIAHSLLYKKVNEAQYRSHLANEMMMYHMKVSDDEYTKLLHDGIQPVAAIDSNFASFTYTPRSLPEDDTSMAILSMLQDMNFINNYKIDCPTLARFCLMVKKGYRDPPYHNWMHAFSVSHFCYLLYKNLELTNYLEDIEIFALFISCMCHDLDHRGTNNSFQVASKSVLAALYSSEGSVMERHHFAQAIAILNTHGCNIFDHFSRKDYQRMLDLMRDIILATDLAHHLRIFKDLQKMAEVGYDRNNKQHHRLLLCLLMTSCDLSDQTKGWKTTRKIAELIYKEFFSQGDLEKAMGNRPMEMMDREKAYIPELQISFMEHIAMPIYKLLQDLFPK-AAELYERVASNREHWTKVS 899

[Close]

BLAST of Phosphodiesterase vs. Ensembl Human
Match: PDE2A (phosphodiesterase 2A [Source:HGNC Symbol;Acc:HGNC:8777])

HSP 1 Score: 757.288 bits (1954), Expect = 0.000e+0
Identity = 373/749 (49.80%), Postives = 525/749 (70.09%), Query Frame = 1

Query:  616 LSFSCQEFNQNEKKLLQTFEN-------QVKVMFQRLERLKNSKDSNLQQSNLQDTKLDSSDFYIDSTILSLCADLHDRDPGILQVKIIRFLKQRIHMESAFILTISNNNLELVCQAQDEQIFDPEKRFRVTDSIFERIMKEKICAQLSDVNMFQDKLNELELLTNIKWNSFLCVPIINQSDGCVSALVCMINKIGSNQSFTAEDISITQHLFQYTAAVLTSSVAFQMERRLKIQTETMLQVAMNIFRKLGDLTGLLKEIMTEAKKLTNAERCSVFLVDNDTKELVSKVFDGLPTISEQSQHPVEIRIPVTQGVAGRVATTGEMLNIVDAYSHPLFYRGVDEETGYKTRNILCFPIKDENEKVVGVAQLCNKINGPCFTNYDEDIAKAFSVYCCISIMHSLMYKKVQDAQHRNKLANELMIYHMQVNEDTVKWLTSCGYPDLMDIKEDFNSFECIPRDIKEHDSALAVLGMFNTLGFISKWRLSRPTLSRFILMIKRGYRDPPYHNWTHAFSVAHFIYLCITNLPLHGQLLPIELLALFVASLCHDIDHRGTNNSFQVTSKSVLAALYSSEGSVLERHHFSQTICVLNSEGCNIFENFSRQDYHHVLDLIRDIILATDLAHHLRIISDQRKMIDTFYDSNSNHHHVLLMDLLMTSADLSDQSKNWKNTRAVAQLIYEEFFSQGDMEKSIGQKPAEQMDRERACVPSLQMSFLDGIALPCFQLFADLYPLFGQKMIENITNNRKKWEKLN 2841
            L   C + + NE+  LQ  E        +V+V+ QR  R       N  +   +D K  ++    D  IL LC +L+D D   LQ+K++++L+Q        +L +S +NL+L C+   +++   E  F +T  + + ++++K   QL D+    + + +L+ +   +  + LCVP+I+++   V AL C  NK+  +  FT ED  + QH F YT+ VLTS++AFQ E++LK + + +LQVA N+F  L D++ LL+EI+TEA+ L+NAE CSVFL+D +  ELV+KVFDG   + ++S    EIRIP  QG+AG VATTG++LNI DAY+HPLFYRGVD+ TG++TRNILCFPIK+EN++V+GVA+L NKINGP F+ +DED+A AFS+YC ISI HSL+YKKV +AQ+R+ LANE+M+YHM+V++D    L   G   +  I  +F SF   PR + E D+++A+L M   + FI+ +++  PTL+RF LM+K+GYRDPPYHNW HAFSV+HF YL   NL L   L  IE+ ALF++ +CHD+DHRGTNNSFQV SKSVLAALYSSEGSV+ERHHF+Q I +LN+ GCNIF++FSR+DY  +LDL+RDIILATDLAHHLRI  D +KM +  YD N+  HH LL+ LLMTS DLSDQ+K WK TR +A+LIY+EFFSQGD+EK++G +P E MDRE+A +P LQ+SF++ IA+P ++L  DL+P    ++ E + +NR+ W K++
Sbjct:   47 LQVHCGQLSDNEEWSLQAVEKHTLVALRRVQVLQQRGPREAPRAVQNPPEGTAEDQKGGAAYTDRDRKILQLCGELYDLDASSLQLKVLQYLQQETRASRCCLLLVSEDNLQLSCKVIGDKVLGEEVSFPLTGCLGQ-VVEDKKSIQLKDLT--SEDVQQLQSMLGCELQAMLCVPVISRATDQVVALACAFNKLEGDL-FTDEDEHVIQHCFHYTSTVLTSTLAFQKEQKLKCECQALLQVAKNLFTHLDDVSVLLQEIITEARNLSNAEICSVFLLDQN--ELVAKVFDG-GVVDDES---YEIRIPADQGIAGHVATTGQILNIPDAYAHPLFYRGVDDSTGFRTRNILCFPIKNENQEVIGVAELVNKINGPWFSKFDEDLATAFSIYCGISIAHSLLYKKVNEAQYRSHLANEMMMYHMKVSDDEYTKLLHDGIQPVAAIDSNFASFTYTPRSLPEDDTSMAILSMLQDMNFINNYKIDCPTLARFCLMVKKGYRDPPYHNWMHAFSVSHFCYLLYKNLELTNYLEDIEIFALFISCMCHDLDHRGTNNSFQVASKSVLAALYSSEGSVMERHHFAQAIAILNTHGCNIFDHFSRKDYQRMLDLMRDIILATDLAHHLRIFKDLQKMAEVGYDRNNKQHHRLLLCLLMTSCDLSDQTKGWKTTRKIAELIYKEFFSQGDLEKAMGNRPMEMMDREKAYIPELQISFMEHIAMPIYKLLQDLFPK-AAELYERVASNREHWTKVS 784

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BLAST of Phosphodiesterase vs. Ensembl Celegans
Match: pde-2 (Probable 3',5'-cyclic phosphodiesterase pde-2 [Source:UniProtKB/Swiss-Prot;Acc:P30645])

HSP 1 Score: 358.221 bits (918), Expect = 6.672e-109
Identity = 204/530 (38.49%), Postives = 304/530 (57.36%), Query Frame = 1

Query: 1318 VAMNIFRKL----GDLTGLLKEIMTEAKKLTNAERCSVFLVDNDTKELVSKVFDGLPTISEQSQHPVEIRIPVTQGVAGRVATTGEMLNIVDAYSHPLFYRGVDEETGYKTRNILCFPIKDENEKVVGVAQLCNKINGPCFTNYDEDIAKAFSVYCCISIMHSLMYKKVQDAQHRNKLANELMIYHMQ--VNEDTVKWLTSCGYPDLMDIKEDFNSFECIPRDIKEHDSALAVLGMFNTLGFISKWRLSRPTLSRFILMIKRGYRDPPYHNWTHAFSVAHFIYLCITNLPLHGQLLPIELLALFVASLCHDIDHRGTNNSFQVTS--KSVLAALYSSEGSVLERHHFSQTICVLNSEGCNIFENFSRQDYHHVLDLIRDIILATDLAHHLRIISDQRKMIDTFYDSNSNHHHVLLMDLLMTSADLSDQSKNWKNTRAVAQLIYEEFFSQGDMEKSIGQKPAEQMDRERACVPSLQMSFLDGIALPCFQLFADLYPLFGQKMIENITNNRKKWEKLNEDIKNGKISANIFQ 2883
            V M+IF +      +L+ L+  I+ EAKK T AE  +VFL D D K++V          + ++      +  +  G+ G+VA+T   +NI D    P F   +DE+   K RN++ FP+ D +  ++GV  L NK NG  F+ +DE   K FS +   SI H+++ K++++ + R  +  E  I      + E  +  L +    D     ++F  F   PR + E+    A +  F  LGF   ++L++  LS  +L +  GYR  PYHNW+HAF+V HF +L +    +   L  +E L+L +A LCHDIDHRGT NSFQ+ S  K+ L+ LYS+EGSVLERHHF+QTI +L  E C+I EN    D+  +++ IR++ILATD++ HLR     + MI   Y+  S  H  LLM L+MT++DLSDQ+KN+ N + +A+ IY EFF+QGD+E  +G KP E MDR  A VP++Q+ FL  I +P FQL A + P  G+   E I  N   W  L+E+++N   + N  +
Sbjct:  163 VPMSIFDQFLCLTNNLSALISCIIAEAKKNTEAEDYAVFLHDEDNKQMV--------LFNNETMLMTGKKFDMGYGIVGKVASTMRTMNIRDVSRCPFFNEEIDEQFSIKARNLIAFPLIDSSCSLIGVIVLYNKENG--FSRHDEKYIKRFSYFVANSIAHAILAKQIEEVRTRIHMVEEFKIQGEDAVIEEVDIMRLVNDPLRDWRYFSQNFADFSFPPRSVGENHFHRASMMFFEDLGFSMLYKLNKRKLSYLVLRVSAGYRPVPYHNWSHAFAVTHFCWLTLRTDAIRRALSDMERLSLLIACLCHDIDHRGTTNSFQMQSLQKTPLSVLYSTEGSVLERHHFAQTIKLLQQEECSILENLPAADFRTIVNTIREVILATDISAHLRKQERIKTMISEGYNPMSFDHRYLLMCLVMTASDLSDQAKNFHNAKRIAENIYLEFFAQGDLELQLGVKPLEMMDRTNAYVPTVQIDFLFKIGVPVFQLLASVVPE-GRTTSEAIDANHLCWVALDEEVRNNPSATNTLE 681

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BLAST of Phosphodiesterase vs. Ensembl Celegans
Match: pde-2 (Probable 3',5'-cyclic phosphodiesterase pde-2 [Source:UniProtKB/Swiss-Prot;Acc:P30645])

HSP 1 Score: 358.221 bits (918), Expect = 7.190e-109
Identity = 204/530 (38.49%), Postives = 304/530 (57.36%), Query Frame = 1

Query: 1318 VAMNIFRKL----GDLTGLLKEIMTEAKKLTNAERCSVFLVDNDTKELVSKVFDGLPTISEQSQHPVEIRIPVTQGVAGRVATTGEMLNIVDAYSHPLFYRGVDEETGYKTRNILCFPIKDENEKVVGVAQLCNKINGPCFTNYDEDIAKAFSVYCCISIMHSLMYKKVQDAQHRNKLANELMIYHMQ--VNEDTVKWLTSCGYPDLMDIKEDFNSFECIPRDIKEHDSALAVLGMFNTLGFISKWRLSRPTLSRFILMIKRGYRDPPYHNWTHAFSVAHFIYLCITNLPLHGQLLPIELLALFVASLCHDIDHRGTNNSFQVTS--KSVLAALYSSEGSVLERHHFSQTICVLNSEGCNIFENFSRQDYHHVLDLIRDIILATDLAHHLRIISDQRKMIDTFYDSNSNHHHVLLMDLLMTSADLSDQSKNWKNTRAVAQLIYEEFFSQGDMEKSIGQKPAEQMDRERACVPSLQMSFLDGIALPCFQLFADLYPLFGQKMIENITNNRKKWEKLNEDIKNGKISANIFQ 2883
            V M+IF +      +L+ L+  I+ EAKK T AE  +VFL D D K++V          + ++      +  +  G+ G+VA+T   +NI D    P F   +DE+   K RN++ FP+ D +  ++GV  L NK NG  F+ +DE   K FS +   SI H+++ K++++ + R  +  E  I      + E  +  L +    D     ++F  F   PR + E+    A +  F  LGF   ++L++  LS  +L +  GYR  PYHNW+HAF+V HF +L +    +   L  +E L+L +A LCHDIDHRGT NSFQ+ S  K+ L+ LYS+EGSVLERHHF+QTI +L  E C+I EN    D+  +++ IR++ILATD++ HLR     + MI   Y+  S  H  LLM L+MT++DLSDQ+KN+ N + +A+ IY EFF+QGD+E  +G KP E MDR  A VP++Q+ FL  I +P FQL A + P  G+   E I  N   W  L+E+++N   + N  +
Sbjct:  160 VPMSIFDQFLCLTNNLSALISCIIAEAKKNTEAEDYAVFLHDEDNKQMV--------LFNNETMLMTGKKFDMGYGIVGKVASTMRTMNIRDVSRCPFFNEEIDEQFSIKARNLIAFPLIDSSCSLIGVIVLYNKENG--FSRHDEKYIKRFSYFVANSIAHAILAKQIEEVRTRIHMVEEFKIQGEDAVIEEVDIMRLVNDPLRDWRYFSQNFADFSFPPRSVGENHFHRASMMFFEDLGFSMLYKLNKRKLSYLVLRVSAGYRPVPYHNWSHAFAVTHFCWLTLRTDAIRRALSDMERLSLLIACLCHDIDHRGTTNSFQMQSLQKTPLSVLYSTEGSVLERHHFAQTIKLLQQEECSILENLPAADFRTIVNTIREVILATDISAHLRKQERIKTMISEGYNPMSFDHRYLLMCLVMTASDLSDQAKNFHNAKRIAENIYLEFFAQGDLELQLGVKPLEMMDRTNAYVPTVQIDFLFKIGVPVFQLLASVVPE-GRTTSEAIDANHLCWVALDEEVRNNPSATNTLE 678

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BLAST of Phosphodiesterase vs. Ensembl Celegans
Match: pde-5 (Probable 3',5'-cyclic phosphodiesterase pde-5 [Source:UniProtKB/Swiss-Prot;Acc:P91119])

HSP 1 Score: 345.51 bits (885), Expect = 3.049e-105
Identity = 198/527 (37.57%), Postives = 304/527 (57.69%), Query Frame = 1

Query: 1309 MLQVAMNIFRKLGDLTGLLKEIMTEAKKLTNAERCSVFLVDNDTKELVSKVFDGLPTISEQ-----SQHPVEIRIPVTQGVAGRVATTGEMLNIVDAYSHPLFYRGVDEETGYKTRNILCFPIKDENEKVVGVAQLCNKINGPCFTNYDEDIAKAFSVYCCISIMHSLMYKKVQDAQHRNKLANELMIYHMQVNEDTVKWLTSCGYPDLMDIKE--DFNSFECIPRDIKEHDSALAVLGMFNTLGFISKWRLSRPTLSRFILMIKRGYRDPPYHNWTHAFSVAHFIYLCITNLPLHGQLLPIELLALFVASLCHDIDHRGTNNSFQVTSKSVLAALYSSEGSVLERHHFSQTICVLNSEGCNIFENFSRQDYHHVLDLIRDIILATDLA------HHLRIISDQRKMIDTFYDSNSNHHHVLLMDLLMTSADLSDQSKNWKNTRAVAQLIYEEFFSQGDMEKSIGQKPAEQMDRERA-CVPSLQMSFLDGIALPCFQLFADLYPLFGQKMIENITNNRKKWEKLNED 2847
            +L VA +IF  +  +  ++ ++M  A+KL +A+R S+FLVD+   ++ +++FD + T  E+     S+   EIR  +++G+AG VA+TGE LNI +AY    F   VD +TGY T+ ILC PI      V+GV Q+ NK +G  FT  DED  + F+VYC +++ H+ +Y K++ ++ + ++A E++ YH   N D V  L      + +   E  DFN        + E +  L  + MF TL F    R     L RF+L +++ YR   YHNW H +SVAH ++  + N P       +E LAL+V+ LCHD+DHRG NN++  T  + LA++YS+  SV+ERHHF+QT+ +L  +G NI ++ S +DY   L LI+  ILATDLA        L +I D     +  +D N   H +L   ++MT  DL   +K W       ++I+EEF+ QGD E+  G++P   MDR++A  +P +Q+ F+ GI +PC+ L A ++P    KM E    N KKWE+L E+
Sbjct:  201 LLDVARSIFHDIVSMDAVIIKVMNFAQKLVDADRASLFLVDSKNAQIYARIFD-VGTGDEEHVRVNSEGQKEIRFDMSKGIAGYVASTGEGLNIENAYEDERFNADVDSKTGYTTKTILCMPILIRG-IVIGVVQMVNKHDG-VFTRQDEDAFEIFAVYCGLALHHAKLYDKIRRSEQKYRVALEVLAYHSVCNADEVNKLKKIEINNRIVELETIDFNGMR-----LSELEKPLYAVYMFKTL-FADTLRFDTEDLIRFVLTVRKNYRRVAYHNWAHGWSVAHAMFATLMNSP--DAFTKLEALALYVSCLCHDLDHRGKNNAYMKTMSTPLASIYST--SVMERHHFNQTVTILQQDGHNILKSLSSEDYKKTLSLIKHCILATDLALFFSNKAKLNVILD-----NNTFDINRQEHRLLTQAVMMTGCDLVASAKPWNIQTETVKVIFEEFYDQGDAERLSGKEPIPMMDRQQAHMLPQMQVGFMRGICMPCYDLIARIFPK-NDKMRERCEYNAKKWEELAEE 708

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BLAST of Phosphodiesterase vs. Ensembl Celegans
Match: pde-4 (Probable 3',5'-cyclic phosphodiesterase pde-4 [Source:UniProtKB/Swiss-Prot;Acc:Q22000])

HSP 1 Score: 135.576 bits (340), Expect = 5.051e-33
Identity = 78/294 (26.53%), Postives = 150/294 (51.02%), Query Frame = 1

Query: 1972 KEHDSALAVLGMFNTLGFISKWRLSRPTLSRFILMIKRGYRDPPYHNWTHAFSVAHFIYLCITNLPLHGQLLPIELLALFVASLCHDIDHRGTNNSFQVTSKSVLAALYSSEGSVLERHHFSQTICVLNSEGCNIFENFSRQDYHHVLDLIRDIILATDLAHHLRIISDQRKMIDTFYDSNSN-------HHHVLLMDLLMTSADLSDQSKNWKNTRAVAQLIYEEFFSQGDMEKSIGQKPAEQMDRERACVPSLQMSFLDGIALPCFQLFADLYPLFGQKMIENITNNRKKWE 2832
            K H   +    +         + + + TL  ++L ++  YR+  YHN+ HA  VA  +++ + +  L      +E+LA   A   HD+DH G  N + + S + LA +Y+ E SVLE+HH +    +L    C+   N SR+       ++ D++LATD++ H+ +++D + M++    + +N       +  + ++  ++  ADLS+ +K  +  +   Q I EE++ QGD EK +G + +   DR    +   Q+ F+D I  P ++ +ADL     Q +++ +  NR+ ++
Sbjct:  237 KNHSLTVVTFSLLRQRNLFKTFEIHQSTLVTYLLNLEHHYRNNHYHNFIHAADVAQSMHVLLMSPVLTEVFTDLEVLAAIFAGAVHDVDHPGFTNQYLINSNNELAIMYNDE-SVLEQHHLAVAFKLLQDSNCDFLANLSRKQRLQFRKIVIDMVLATDMSKHMSLLADLKTMVEAKKVAGNNVIVLDKYNDKIQVLQSMIHLADLSNPTKPIELYQQWNQRIMEEYWRQGDKEKELGLEISPMCDRGNVTIEKSQVGFIDYIVHPLYETWADLVYPDAQNILDQLEENREWYQ 529

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BLAST of Phosphodiesterase vs. Ensembl Celegans
Match: pde-4 (Probable 3',5'-cyclic phosphodiesterase pde-4 [Source:UniProtKB/Swiss-Prot;Acc:Q22000])

HSP 1 Score: 134.806 bits (338), Expect = 2.400e-32
Identity = 78/294 (26.53%), Postives = 150/294 (51.02%), Query Frame = 1

Query: 1972 KEHDSALAVLGMFNTLGFISKWRLSRPTLSRFILMIKRGYRDPPYHNWTHAFSVAHFIYLCITNLPLHGQLLPIELLALFVASLCHDIDHRGTNNSFQVTSKSVLAALYSSEGSVLERHHFSQTICVLNSEGCNIFENFSRQDYHHVLDLIRDIILATDLAHHLRIISDQRKMIDTFYDSNSN-------HHHVLLMDLLMTSADLSDQSKNWKNTRAVAQLIYEEFFSQGDMEKSIGQKPAEQMDRERACVPSLQMSFLDGIALPCFQLFADLYPLFGQKMIENITNNRKKWE 2832
            K H   +    +         + + + TL  ++L ++  YR+  YHN+ HA  VA  +++ + +  L      +E+LA   A   HD+DH G  N + + S + LA +Y+ E SVLE+HH +    +L    C+   N SR+       ++ D++LATD++ H+ +++D + M++    + +N       +  + ++  ++  ADLS+ +K  +  +   Q I EE++ QGD EK +G + +   DR    +   Q+ F+D I  P ++ +ADL     Q +++ +  NR+ ++
Sbjct:  312 KNHSLTVVTFSLLRQRNLFKTFEIHQSTLVTYLLNLEHHYRNNHYHNFIHAADVAQSMHVLLMSPVLTEVFTDLEVLAAIFAGAVHDVDHPGFTNQYLINSNNELAIMYNDE-SVLEQHHLAVAFKLLQDSNCDFLANLSRKQRLQFRKIVIDMVLATDMSKHMSLLADLKTMVEAKKVAGNNVIVLDKYNDKIQVLQSMIHLADLSNPTKPIELYQQWNQRIMEEYWRQGDKEKELGLEISPMCDRGNVTIEKSQVGFIDYIVHPLYETWADLVYPDAQNILDQLEENREWYQ 604

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BLAST of Phosphodiesterase vs. Ensembl Fly
Match: Pde6 (gene:FBgn0038237 transcript:FBtr0300330)

HSP 1 Score: 330.102 bits (845), Expect = 3.103e-96
Identity = 206/642 (32.09%), Postives = 331/642 (51.56%), Query Frame = 1

Query: 1072 ELELLTNIKWNSFLCVPIINQSDGCVSALVCMINKIGSNQSFTAEDISITQHLFQYTAAVLTSSVAFQMERRLKIQTETMLQVAMNIFRKLGDLTGLLKEIMTEAKKLTNAERCSVFLVDNDTKELVSKVFDGLPTISEQSQHPV----------------------------------------EIRIPVTQGVAGRVATTGEMLNIVDAYSHPLFYRGVDEETGY-KTRNILCFPIKDENEKVVGVAQLCNKINGPCFTNYDEDIAKAFSVYCCISIMHSLMYKKVQDAQHRNKLANELMIYHMQVNEDTVKWLTSCGYPDLMDIKEDFN--SFECIPRDIKEHDSALAVLGMFNTLGFISKWRLSRPTLSRFILMIKRGYRDPPYHNWTHAFSVAHFIYLCITNLPLHGQLLPIELLALFVASLCHDIDHRGTNNSFQVTSKSVLAALYSSEGSVLERHHFSQTICVLNSEGCNIFENFSRQDYHHVLDLIRDIILATDLAHHLRIISDQRKMIDTF-YDSNSNHHHVLLMDLLMTSADLSDQSKNWKNTRAVAQLIYEEFFSQGDMEK-SIGQKPAEQMDRERAC-VPSLQMSFLDGIALPCFQLFADLYPLFGQKMIENITNNRKKWEKLNEDIKNG 2859
            E++L T  K N+ LC+PI N  +G +  +  +INK      F   D+ I +    +    + ++  F+M  +   + + +L +A +IF +  +L  L+ +IMTEA++L   ERCSVFLVD D  E        L  I E+   P                                         E+       +A  VATTG+ +NI D       +  +  E     T+ ILC PI +  +KV+GVAQL NK NG  FT+ D  I +AF+++C + I ++ MY+       + K+A E + YH   ++D  + LT     D++   E +N  SF     ++ + D+  AVL MF     +S++++    L R++L +++ YR   YHNW HA +VA  ++  +    +   +  +E+L L VA LCHD+DHRGTNN+FQ  ++S LA LY++  S +E HHF Q + +LNSEG NIF+  S +DY  V+  +   IL+TDLA + +  +   ++++   +D        LL  ++MT+ D+S  +K W+    VA+L+ +EFF QGD+EK  +  +P   MDRER   +P +Q+ F+D I LP +++  D +P     + E    NR+ W+ L E ++ G
Sbjct:  340 EIDLKTGYKTNAILCMPICNY-EGDIIGVAQIINKTNGCMEFDEHDVEIFRRYLTFCGIGIQNAQLFEMSVQEYRRNQILLNLARSIFEEQNNLECLVTKIMTEARELLKCERCSVFLVDLDCCEA-----SHLEKIIEKPNQPATRAIKSADSFEEKKMRNRFTVLFELGGEYQAANVSRPSVSELSSSTLAQIAQFVATTGQTVNICDVIEWVRDHNQIRAEDEIDSTQAILCMPIMNAQKKVIGVAQLINKANGVPFTDSDASIFEAFAIFCGLGIHNTQMYENACKLMAKQKVALECLSYHATASQDQTEKLTQ----DVIAEAESYNLYSFTFTDFELVDDDTCRAVLRMFMQCNLVSQFQIPYDVLCRWVLSVRKNYRPVKYHNWRHALNVAQTMFAMLKTGKMERFMTDLEILGLLVACLCHDLDHRGTNNAFQTKTESPLAILYTT--STMEHHHFDQCVMILNSEGNNIFQALSPEDYRSVMKTVESAILSTDLAMYFKKRNAFLELVENGEFDWQGEEKKDLLCGMMMTACDVSAIAKPWEVQHKVAKLVADEFFDQGDLEKLQLNTQPVAMMDRERKDELPKMQVGFIDVICLPLYRVLCDTFPWI-TPLYEGTLENRRNWQDLAEKVEMG 968

HSP 2 Score: 90.5077 bits (223), Expect = 4.898e-18
Identity = 60/172 (34.88%), Postives = 92/172 (53.49%), Query Frame = 1

Query: 1348 DLTGLLKEIMTEAKKLTNAERCSVFLVDND--TKELVSKVFDGLPTISEQSQ----HPVEIRIPVTQGVAGRVATTGEMLNIVDAYSHPLFYRGVDEETGYKTRNILCFPIKDENEKVVGVAQLCNKINGPC--FTNYDEDIAKAFSVYCCISIMHSLMYKKVQDAQHRNKL 1839
            D+  L  +I+     LT+A+R S+FL       K LV+K+FD     + +         EI IP   G+AG VA T +M+NI +AY    F   +D +TGYKT  ILC PI +    ++GVAQ+ NK NG C  F  +D +I + +  +C I I ++ +++       RN++
Sbjct:  247 DIDVLCHKILVNVGLLTHADRGSLFLAKGTPTNKYLVAKLFDVTQKTALKDAVTRASAEEIIIPFGIGIAGMVAQTKQMINIKEAYKDARFNCEIDLKTGYKTNAILCMPICNYEGDIIGVAQIINKTNG-CMEFDEHDVEIFRRYLTFCGIGIQNAQLFEMSVQEYRRNQI 417

[Close]

BLAST of Phosphodiesterase vs. Ensembl Fly
Match: Pde6 (gene:FBgn0038237 transcript:FBtr0345168)

HSP 1 Score: 330.102 bits (845), Expect = 3.103e-96
Identity = 206/642 (32.09%), Postives = 331/642 (51.56%), Query Frame = 1

Query: 1072 ELELLTNIKWNSFLCVPIINQSDGCVSALVCMINKIGSNQSFTAEDISITQHLFQYTAAVLTSSVAFQMERRLKIQTETMLQVAMNIFRKLGDLTGLLKEIMTEAKKLTNAERCSVFLVDNDTKELVSKVFDGLPTISEQSQHPV----------------------------------------EIRIPVTQGVAGRVATTGEMLNIVDAYSHPLFYRGVDEETGY-KTRNILCFPIKDENEKVVGVAQLCNKINGPCFTNYDEDIAKAFSVYCCISIMHSLMYKKVQDAQHRNKLANELMIYHMQVNEDTVKWLTSCGYPDLMDIKEDFN--SFECIPRDIKEHDSALAVLGMFNTLGFISKWRLSRPTLSRFILMIKRGYRDPPYHNWTHAFSVAHFIYLCITNLPLHGQLLPIELLALFVASLCHDIDHRGTNNSFQVTSKSVLAALYSSEGSVLERHHFSQTICVLNSEGCNIFENFSRQDYHHVLDLIRDIILATDLAHHLRIISDQRKMIDTF-YDSNSNHHHVLLMDLLMTSADLSDQSKNWKNTRAVAQLIYEEFFSQGDMEK-SIGQKPAEQMDRERAC-VPSLQMSFLDGIALPCFQLFADLYPLFGQKMIENITNNRKKWEKLNEDIKNG 2859
            E++L T  K N+ LC+PI N  +G +  +  +INK      F   D+ I +    +    + ++  F+M  +   + + +L +A +IF +  +L  L+ +IMTEA++L   ERCSVFLVD D  E        L  I E+   P                                         E+       +A  VATTG+ +NI D       +  +  E     T+ ILC PI +  +KV+GVAQL NK NG  FT+ D  I +AF+++C + I ++ MY+       + K+A E + YH   ++D  + LT     D++   E +N  SF     ++ + D+  AVL MF     +S++++    L R++L +++ YR   YHNW HA +VA  ++  +    +   +  +E+L L VA LCHD+DHRGTNN+FQ  ++S LA LY++  S +E HHF Q + +LNSEG NIF+  S +DY  V+  +   IL+TDLA + +  +   ++++   +D        LL  ++MT+ D+S  +K W+    VA+L+ +EFF QGD+EK  +  +P   MDRER   +P +Q+ F+D I LP +++  D +P     + E    NR+ W+ L E ++ G
Sbjct:  340 EIDLKTGYKTNAILCMPICNY-EGDIIGVAQIINKTNGCMEFDEHDVEIFRRYLTFCGIGIQNAQLFEMSVQEYRRNQILLNLARSIFEEQNNLECLVTKIMTEARELLKCERCSVFLVDLDCCEA-----SHLEKIIEKPNQPATRAIKSADSFEEKKMRNRFTVLFELGGEYQAANVSRPSVSELSSSTLAQIAQFVATTGQTVNICDVIEWVRDHNQIRAEDEIDSTQAILCMPIMNAQKKVIGVAQLINKANGVPFTDSDASIFEAFAIFCGLGIHNTQMYENACKLMAKQKVALECLSYHATASQDQTEKLTQ----DVIAEAESYNLYSFTFTDFELVDDDTCRAVLRMFMQCNLVSQFQIPYDVLCRWVLSVRKNYRPVKYHNWRHALNVAQTMFAMLKTGKMERFMTDLEILGLLVACLCHDLDHRGTNNAFQTKTESPLAILYTT--STMEHHHFDQCVMILNSEGNNIFQALSPEDYRSVMKTVESAILSTDLAMYFKKRNAFLELVENGEFDWQGEEKKDLLCGMMMTACDVSAIAKPWEVQHKVAKLVADEFFDQGDLEKLQLNTQPVAMMDRERKDELPKMQVGFIDVICLPLYRVLCDTFPWI-TPLYEGTLENRRNWQDLAEKVEMG 968

HSP 2 Score: 90.5077 bits (223), Expect = 4.898e-18
Identity = 60/172 (34.88%), Postives = 92/172 (53.49%), Query Frame = 1

Query: 1348 DLTGLLKEIMTEAKKLTNAERCSVFLVDND--TKELVSKVFDGLPTISEQSQ----HPVEIRIPVTQGVAGRVATTGEMLNIVDAYSHPLFYRGVDEETGYKTRNILCFPIKDENEKVVGVAQLCNKINGPC--FTNYDEDIAKAFSVYCCISIMHSLMYKKVQDAQHRNKL 1839
            D+  L  +I+     LT+A+R S+FL       K LV+K+FD     + +         EI IP   G+AG VA T +M+NI +AY    F   +D +TGYKT  ILC PI +    ++GVAQ+ NK NG C  F  +D +I + +  +C I I ++ +++       RN++
Sbjct:  247 DIDVLCHKILVNVGLLTHADRGSLFLAKGTPTNKYLVAKLFDVTQKTALKDAVTRASAEEIIIPFGIGIAGMVAQTKQMINIKEAYKDARFNCEIDLKTGYKTNAILCMPICNYEGDIIGVAQIINKTNG-CMEFDEHDVEIFRRYLTFCGIGIQNAQLFEMSVQEYRRNQI 417

[Close]

BLAST of Phosphodiesterase vs. Ensembl Fly
Match: Pde6 (gene:FBgn0038237 transcript:FBtr0330048)

HSP 1 Score: 330.102 bits (845), Expect = 3.477e-96
Identity = 206/642 (32.09%), Postives = 331/642 (51.56%), Query Frame = 1

Query: 1072 ELELLTNIKWNSFLCVPIINQSDGCVSALVCMINKIGSNQSFTAEDISITQHLFQYTAAVLTSSVAFQMERRLKIQTETMLQVAMNIFRKLGDLTGLLKEIMTEAKKLTNAERCSVFLVDNDTKELVSKVFDGLPTISEQSQHPV----------------------------------------EIRIPVTQGVAGRVATTGEMLNIVDAYSHPLFYRGVDEETGY-KTRNILCFPIKDENEKVVGVAQLCNKINGPCFTNYDEDIAKAFSVYCCISIMHSLMYKKVQDAQHRNKLANELMIYHMQVNEDTVKWLTSCGYPDLMDIKEDFN--SFECIPRDIKEHDSALAVLGMFNTLGFISKWRLSRPTLSRFILMIKRGYRDPPYHNWTHAFSVAHFIYLCITNLPLHGQLLPIELLALFVASLCHDIDHRGTNNSFQVTSKSVLAALYSSEGSVLERHHFSQTICVLNSEGCNIFENFSRQDYHHVLDLIRDIILATDLAHHLRIISDQRKMIDTF-YDSNSNHHHVLLMDLLMTSADLSDQSKNWKNTRAVAQLIYEEFFSQGDMEK-SIGQKPAEQMDRERAC-VPSLQMSFLDGIALPCFQLFADLYPLFGQKMIENITNNRKKWEKLNEDIKNG 2859
            E++L T  K N+ LC+PI N  +G +  +  +INK      F   D+ I +    +    + ++  F+M  +   + + +L +A +IF +  +L  L+ +IMTEA++L   ERCSVFLVD D  E        L  I E+   P                                         E+       +A  VATTG+ +NI D       +  +  E     T+ ILC PI +  +KV+GVAQL NK NG  FT+ D  I +AF+++C + I ++ MY+       + K+A E + YH   ++D  + LT     D++   E +N  SF     ++ + D+  AVL MF     +S++++    L R++L +++ YR   YHNW HA +VA  ++  +    +   +  +E+L L VA LCHD+DHRGTNN+FQ  ++S LA LY++  S +E HHF Q + +LNSEG NIF+  S +DY  V+  +   IL+TDLA + +  +   ++++   +D        LL  ++MT+ D+S  +K W+    VA+L+ +EFF QGD+EK  +  +P   MDRER   +P +Q+ F+D I LP +++  D +P     + E    NR+ W+ L E ++ G
Sbjct:  340 EIDLKTGYKTNAILCMPICNY-EGDIIGVAQIINKTNGCMEFDEHDVEIFRRYLTFCGIGIQNAQLFEMSVQEYRRNQILLNLARSIFEEQNNLECLVTKIMTEARELLKCERCSVFLVDLDCCEA-----SHLEKIIEKPNQPATRAIKSADSFEEKKMRNRFTVLFELGGEYQAANVSRPSVSELSSSTLAQIAQFVATTGQTVNICDVIEWVRDHNQIRAEDEIDSTQAILCMPIMNAQKKVIGVAQLINKANGVPFTDSDASIFEAFAIFCGLGIHNTQMYENACKLMAKQKVALECLSYHATASQDQTEKLTQ----DVIAEAESYNLYSFTFTDFELVDDDTCRAVLRMFMQCNLVSQFQIPYDVLCRWVLSVRKNYRPVKYHNWRHALNVAQTMFAMLKTGKMERFMTDLEILGLLVACLCHDLDHRGTNNAFQTKTESPLAILYTT--STMEHHHFDQCVMILNSEGNNIFQALSPEDYRSVMKTVESAILSTDLAMYFKKRNAFLELVENGEFDWQGEEKKDLLCGMMMTACDVSAIAKPWEVQHKVAKLVADEFFDQGDLEKLQLNTQPVAMMDRERKDELPKMQVGFIDVICLPLYRVLCDTFPWI-TPLYEGTLENRRNWQDLAEKVEMG 968

HSP 2 Score: 90.5077 bits (223), Expect = 5.125e-18
Identity = 60/172 (34.88%), Postives = 92/172 (53.49%), Query Frame = 1

Query: 1348 DLTGLLKEIMTEAKKLTNAERCSVFLVDND--TKELVSKVFDGLPTISEQSQ----HPVEIRIPVTQGVAGRVATTGEMLNIVDAYSHPLFYRGVDEETGYKTRNILCFPIKDENEKVVGVAQLCNKINGPC--FTNYDEDIAKAFSVYCCISIMHSLMYKKVQDAQHRNKL 1839
            D+  L  +I+     LT+A+R S+FL       K LV+K+FD     + +         EI IP   G+AG VA T +M+NI +AY    F   +D +TGYKT  ILC PI +    ++GVAQ+ NK NG C  F  +D +I + +  +C I I ++ +++       RN++
Sbjct:  247 DIDVLCHKILVNVGLLTHADRGSLFLAKGTPTNKYLVAKLFDVTQKTALKDAVTRASAEEIIIPFGIGIAGMVAQTKQMINIKEAYKDARFNCEIDLKTGYKTNAILCMPICNYEGDIIGVAQIINKTNG-CMEFDEHDVEIFRRYLTFCGIGIQNAQLFEMSVQEYRRNQI 417

[Close]

BLAST of Phosphodiesterase vs. Ensembl Fly
Match: Pde11 (gene:FBgn0085370 transcript:FBtr0303163)

HSP 1 Score: 315.849 bits (808), Expect = 4.200e-91
Identity = 204/610 (33.44%), Postives = 318/610 (52.13%), Query Frame = 1

Query: 1072 ELELLTNIKWNSFLCVPIINQSDGCVSALVCMINKIGSNQSFTAEDISITQHLFQYTAAVLTSSVAFQMERRLKIQTETMLQVAMNIFRKLGDLTGLLKEIMTEAKKLTNAERCSVFLVDNDTKELVSKVFD-GLPTISEQSQ----HPVEIRIPVTQGVAGRVATTGEMLNIVDAYSHPLFYRGVDEETGYKTRNILCFPIKDENEKVVGVAQLCNKINGPCFTNYDEDIAKAFSVYCCISIMHSLMYKKVQDAQHRNKLANELMIYHMQVNEDTVKWLTSCGYPD-----LMDIKEDFNSFECIPRDIKEHDSALAVLGMFNTLGFISKWRLSRPTLSRFILMIKRGYRDPPYHNWTHAFSVAHFIYLCITNLPLHGQLLPIELLALFVASLCHDIDHRGTNNSFQVTSKSVLAALYSSEGSVLERHHFSQTICVLNSEGCNIFENFSRQDYHHVLDLIRDIILATDLAHHLRIISDQRKMIDTFYDSNS----NHHHVLLMDLLMTSADLSDQSKNWKNTRAVAQLIYEEFFSQGDMEK-SIGQKPAEQMDRERAC-VPSLQMSFLDGIALPCFQLFADLYPLFGQKMIENITNNRKKWEKLNEDIK 2853
            E++ LT  +  + LC+PI   S G V  +  +INK+ + + F+  D  +     Q+    L ++  ++  +    + + +L +A  IF +   +  ++  I+T  + L   +R  + LV    K   S+VFD     +SE+       P E R P+  G+ G VATTGE +N+ +AY    F   VDE + +K R+ILC  IK+   +++GV QL NK N   FT  DE+  +AF+++C + I ++ MY+K   A  +  +  E++ YH     D    L     P      L D K D   FE       + D+  A L MF  L F+ ++ +    L R++L +K+ YR+  YHNW HAF+VA  ++  +T          IE LAL +  LCHD+DHRGTNNSFQ+ + S LA LYS+  S +E HHF Q + +LNS G  I  N S  DY  V+ ++ D IL+TDLA + +    +   +++     S         LL  + MT  DLS  +K W+  + VA L+  EFF QGDMEK  +   P + M+RE+   +P +Q++F+D I LP ++ FA L     + ++E + +NR  W  L + +K
Sbjct:  470 EIDSLTGYRTKALLCMPI-KDSSGDVIGVAQVINKM-NGECFSEIDEKVFSSYLQFCGIGLRNAQLYEKSQLEIKRNQVLLDLARMIFEEQSTIEHMVFRILTHMQSLIQCQRVQILLVHEADKGSFSRVFDFEANDLSEEEATSRTSPYESRFPINIGITGHVATTGETVNVPNAYEDDRFDASVDENSCFKHRSILCMAIKNSLGQIIGVIQLINKFNELDFTKNDENFVEAFAIFCGMGIHNTHMYEKAIVAMAKQSVTLEVLSYHASATMDEAHRLRRLRVPSAVHFRLHDFKFDDIHFE-------DDDTLKACLRMFLDLDFVERFHIDYEVLCRWLLSVKKNYRNVTYHNWRHAFNVAQMMFAILTTTQWWKIFGEIECLALIIGCLCHDLDHRGTNNSFQIKASSPLAQLYST--STMEHHHFDQCLMILNSPGNQILANLSSDDYCRVIRVLEDAILSTDLAVYFK---KRGPFLESVSQPTSYWVAEEPRALLRAMSMTVCDLSAITKPWEIEKRVADLVSSEFFEQGDMEKQELNITPIDIMNREKEDELPMMQVNFIDSICLPIYEAFATLSDKL-EPLVEGVRDNRGHWIDLADVVK 1064

HSP 2 Score: 120.553 bits (301), Expect = 2.814e-27
Identity = 75/202 (37.13%), Postives = 116/202 (57.43%), Query Frame = 1

Query: 1297 QTETMLQVAMNIFRKLGDLTGLLKEIMTEAKKLTNAERCSVFLV-------DNDTKELVSKVFDGLP--TISEQSQHPVEIRIPVTQGVAGRVATTGEMLNIVDAYSHPLFYRGVDEETGYKTRNILCFPIKDENEKVVGVAQLCNKINGPCFTNYDEDIAKAFSVYCCISIMHSLMYKKVQDAQHRNKLANEL--MIYHMQ 1869
            + E + ++  +I  +L ++  L  +I+     L NA+R S+FLV       D   K LVSK+FD  P  T+ E  Q   E+R+    G+AG VA +GE +NI DAY    F   +D  TGY+T+ +LC PIKD +  V+GVAQ+ NK+NG CF+  DE +  ++  +C I + ++ +Y+K Q    RN++  +L  MI+  Q
Sbjct:  359 EKELIFELVKDICNEL-EVRTLCHKILQNVSILLNADRGSLFLVQGRCNGPDGLKKCLVSKLFDVCPRSTVEEMEQQD-EVRVAWGTGIAGHVAESGEPVNIPDAYQDERFNCEIDSLTGYRTKALLCMPIKDSSGDVIGVAQVINKMNGECFSEIDEKVFSSYLQFCGIGLRNAQLYEKSQLEIKRNQVLLDLARMIFEEQ 558

[Close]

BLAST of Phosphodiesterase vs. Ensembl Fly
Match: Pde11 (gene:FBgn0085370 transcript:FBtr0303162)

HSP 1 Score: 315.079 bits (806), Expect = 1.179e-90
Identity = 204/610 (33.44%), Postives = 318/610 (52.13%), Query Frame = 1

Query: 1072 ELELLTNIKWNSFLCVPIINQSDGCVSALVCMINKIGSNQSFTAEDISITQHLFQYTAAVLTSSVAFQMERRLKIQTETMLQVAMNIFRKLGDLTGLLKEIMTEAKKLTNAERCSVFLVDNDTKELVSKVFD-GLPTISEQSQ----HPVEIRIPVTQGVAGRVATTGEMLNIVDAYSHPLFYRGVDEETGYKTRNILCFPIKDENEKVVGVAQLCNKINGPCFTNYDEDIAKAFSVYCCISIMHSLMYKKVQDAQHRNKLANELMIYHMQVNEDTVKWLTSCGYPD-----LMDIKEDFNSFECIPRDIKEHDSALAVLGMFNTLGFISKWRLSRPTLSRFILMIKRGYRDPPYHNWTHAFSVAHFIYLCITNLPLHGQLLPIELLALFVASLCHDIDHRGTNNSFQVTSKSVLAALYSSEGSVLERHHFSQTICVLNSEGCNIFENFSRQDYHHVLDLIRDIILATDLAHHLRIISDQRKMIDTFYDSNS----NHHHVLLMDLLMTSADLSDQSKNWKNTRAVAQLIYEEFFSQGDMEK-SIGQKPAEQMDRERAC-VPSLQMSFLDGIALPCFQLFADLYPLFGQKMIENITNNRKKWEKLNEDIK 2853
            E++ LT  +  + LC+PI   S G V  +  +INK+ + + F+  D  +     Q+    L ++  ++  +    + + +L +A  IF +   +  ++  I+T  + L   +R  + LV    K   S+VFD     +SE+       P E R P+  G+ G VATTGE +N+ +AY    F   VDE + +K R+ILC  IK+   +++GV QL NK N   FT  DE+  +AF+++C + I ++ MY+K   A  +  +  E++ YH     D    L     P      L D K D   FE       + D+  A L MF  L F+ ++ +    L R++L +K+ YR+  YHNW HAF+VA  ++  +T          IE LAL +  LCHD+DHRGTNNSFQ+ + S LA LYS+  S +E HHF Q + +LNS G  I  N S  DY  V+ ++ D IL+TDLA + +    +   +++     S         LL  + MT  DLS  +K W+  + VA L+  EFF QGDMEK  +   P + M+RE+   +P +Q++F+D I LP ++ FA L     + ++E + +NR  W  L + +K
Sbjct:  514 EIDSLTGYRTKALLCMPI-KDSSGDVIGVAQVINKM-NGECFSEIDEKVFSSYLQFCGIGLRNAQLYEKSQLEIKRNQVLLDLARMIFEEQSTIEHMVFRILTHMQSLIQCQRVQILLVHEADKGSFSRVFDFEANDLSEEEATSRTSPYESRFPINIGITGHVATTGETVNVPNAYEDDRFDASVDENSCFKHRSILCMAIKNSLGQIIGVIQLINKFNELDFTKNDENFVEAFAIFCGMGIHNTHMYEKAIVAMAKQSVTLEVLSYHASATMDEAHRLRRLRVPSAVHFRLHDFKFDDIHFE-------DDDTLKACLRMFLDLDFVERFHIDYEVLCRWLLSVKKNYRNVTYHNWRHAFNVAQMMFAILTTTQWWKIFGEIECLALIIGCLCHDLDHRGTNNSFQIKASSPLAQLYST--STMEHHHFDQCLMILNSPGNQILANLSSDDYCRVIRVLEDAILSTDLAVYFK---KRGPFLESVSQPTSYWVAEEPRALLRAMSMTVCDLSAITKPWEIEKRVADLVSSEFFEQGDMEKQELNITPIDIMNREKEDELPMMQVNFIDSICLPIYEAFATLSDKL-EPLVEGVRDNRGHWIDLADVVK 1108

HSP 2 Score: 120.168 bits (300), Expect = 3.725e-27
Identity = 75/202 (37.13%), Postives = 116/202 (57.43%), Query Frame = 1

Query: 1297 QTETMLQVAMNIFRKLGDLTGLLKEIMTEAKKLTNAERCSVFLV-------DNDTKELVSKVFDGLP--TISEQSQHPVEIRIPVTQGVAGRVATTGEMLNIVDAYSHPLFYRGVDEETGYKTRNILCFPIKDENEKVVGVAQLCNKINGPCFTNYDEDIAKAFSVYCCISIMHSLMYKKVQDAQHRNKLANEL--MIYHMQ 1869
            + E + ++  +I  +L ++  L  +I+     L NA+R S+FLV       D   K LVSK+FD  P  T+ E  Q   E+R+    G+AG VA +GE +NI DAY    F   +D  TGY+T+ +LC PIKD +  V+GVAQ+ NK+NG CF+  DE +  ++  +C I + ++ +Y+K Q    RN++  +L  MI+  Q
Sbjct:  403 EKELIFELVKDICNEL-EVRTLCHKILQNVSILLNADRGSLFLVQGRCNGPDGLKKCLVSKLFDVCPRSTVEEMEQQD-EVRVAWGTGIAGHVAESGEPVNIPDAYQDERFNCEIDSLTGYRTKALLCMPIKDSSGDVIGVAQVINKMNGECFSEIDEKVFSSYLQFCGIGLRNAQLYEKSQLEIKRNQVLLDLARMIFEEQ 602

[Close]

BLAST of Phosphodiesterase vs. Ensembl Zebrafish
Match: pde11a (phosphodiesterase 11a [Source:ZFIN;Acc:ZDB-GENE-070912-207])

HSP 1 Score: 340.887 bits (873), Expect = 1.028e-101
Identity = 199/605 (32.89%), Postives = 336/605 (55.54%), Query Frame = 1

Query: 1069 NELELLTNIKWNSFLCVPIINQSDGCVSALVCMINKIGSNQSFTAEDISITQHLFQYTAAVLTSSVAFQMERRLKIQTETMLQVAMNIFRKLGDLTGLLKEIMTEAKKLTNAERCSVFLVDNDTKELV--SKVFDGL-PTISEQSQHPVEIRIP--------VTQGVAGRVATTGEMLNIVDAYSHPLFYRGVDEETGYKTRNILCFPIKDENEKVVGVAQLCNKINGPCFTNYDEDIAKAFSVYCCISIMHSLMYKKVQDAQHRNKLANELMIYHMQVNEDTVKWLTSCGYPDLMDIKEDFNSFECIPRDIKEHDSALAVLGMFNTLGFISKWRLSRPTLSRFILMIKRGYRDPPYHNWTHAFSVAHFIYLCITNLPLHGQLLPIELLALFVASLCHDIDHRGTNNSFQVTSKSVLAALYSSEGSVLERHHFSQTICVLNSEGCNIFENFSRQDYHHVLDLIRDIILATDLAHHLRIISDQRKMIDTF-YDSNSNHHHVLLMDLLMTSADLSDQSKNWKNTRAVAQLIYEEFFSQGDMEKS-IGQKPAEQMDRERAC-VPSLQMSFLDGIALPCFQLFADLYPLFGQKMIENITNNRKKWEKLN 2841
            +E++ LT  K  S LC+PI N SDG V  +   INK  +   FT +D  + Q    +    ++++  F   R+   ++  +L+V  ++F +  DL  ++++IM  A+ L   ERCSV L+++    +V  +K F+ L P  S   ++  +  +         +   +A  VA+TG  +NI DAY  P F    D+ +G+  R++LC PI + N +++GVAQ+ N+++G  F + D+ + +AF ++C + I +++MY +V+ +  +  +A +++ YH   ++  V    +   P + ++  D  SF+    D+       A L MF  LG + K+++   TL R++L +++ YR   YHNW HAF+V   ++  +T       L  +E LAL V  +CHD+DHRGTNN+FQ  + S L+ LY +  + LE HHF+  + +L SEG NIF N S  +Y  ++ L++  ILATDL  + +  +   ++++   Y+ N   H  +   +LMT+ DL   +K W+ +  VA+L+  EFF QGD E+S +   P+   DR R   +P LQ+ ++DGI  P ++ FA L P   Q M++ I  NR KWE+L+
Sbjct:  260 DEIDKLTGYKTKSLLCMPIHN-SDGEVIGVAQAINKSPNGALFTQDDEKVLQMYLPFCGIAISNAQLFAASRKEYDRSRALLEVVNDLFEEQTDLEKIVRKIMHRAQTLLKCERCSVQLLEDIESPVVKFTKSFELLSPKCSADMENSFKDSMDKSSYSDWLINNSIAELVASTGLPVNISDAYQDPRFDAEADQFSGFHIRSVLCVPIWNSNHQIIGVAQVLNRLDGKPFDDADQRLFEAFVIFCGLGINNTIMYDQVKKSWAKQSVALDVLSYHATCSKTEVDKFKAANIPLVCELGIDKLSFDDFSLDVDA--MVTAALRMFMELGMVQKFKIDYETLCRWLLTVRKNYRMVLYHNWRHAFNVCQCMFSMLTTAGFQETLTEMETLALIVGCICHDLDHRGTNNAFQAKTGSALSLLYGTSAT-LEHHHFNHAVMILQSEGHNIFSNLSSHEYGELMQLLKQSILATDLTLYFQNRNSFFELVNKGEYNWNVKEHREMCRSMLMTACDLGAVTKPWEISHKVAELVTSEFFEQGDRERSELKLTPSAIFDRNRKDELPGLQLEWIDGICAPLYETFAKLNPKL-QPMMDLIKANRAKWEELH 859

HSP 2 Score: 108.997 bits (271), Expect = 1.113e-23
Identity = 68/189 (35.98%), Postives = 108/189 (57.14%), Query Frame = 1

Query: 1297 QTETMLQVAMNIFRKLGDLTGLLKEIMTEAKKLTNAERCSVFLVDNDT--KELVSKVFDG------LPTISEQSQHPVEIRIPVTQGVAGRVATTGEMLNIVDAYSHPLFYRGVDEETGYKTRNILCFPIKDENEKVVGVAQLCNK-INGPCFTNYDEDIAKAFSVYCCISIMHSLMYKKVQDAQHRNK 1836
            + E  L++  +I   L DLT L  +I+     + +A+RCS+FLV+  T  K LVSK FD       LP++S       E+++P  +G+ G VA  GE +NI DAY    F   +D+ TGYKT+++LC PI + + +V+GVAQ  NK  NG  FT  DE + + +  +C I+I ++ ++   +    R++
Sbjct:  154 EREFFLELVKDISNDL-DLTSLSYKILVFVCIMVDADRCSLFLVEGPTNKKTLVSKFFDVHAGTTVLPSLSNSD----EVQVPWGKGIIGYVAEHGETVNIPDAYQDHRFSDEIDKLTGYKTKSLLCMPIHNSDGEVIGVAQAINKSPNGALFTQDDEKVLQMYLPFCGIAISNAQLFAASRKEYDRSR 337

[Close]

BLAST of Phosphodiesterase vs. Ensembl Zebrafish
Match: pde10a (phosphodiesterase 10A [Source:ZFIN;Acc:ZDB-GENE-040426-1115])

HSP 1 Score: 334.724 bits (857), Expect = 2.304e-100
Identity = 217/604 (35.93%), Postives = 333/604 (55.13%), Query Frame = 1

Query: 1087 TNIKWNSFLCVPIINQSDGCVSALVCMINKIGSNQSFTAEDISITQHLFQYTAAVLTSSVAF---QMERRLKIQTET---MLQVAMNIFRKLGDLTGLLKEIMTEAKKLTNAERCSVFLVDNDTKELVSKVFDGLPTISEQSQ-HPV-----EIRIPVTQGVAGRVATTGEMLNIVDAYSHPLFYRGVDEETGYKTRNILCFPIKDENEKVVGVAQLCNKINGPCFTNYDEDIAKAFSVYCCISIMHSLMYKKVQDAQHRNKLANELMIYHMQVNEDTVKWLTSCGYPDLMDIKEDFNSFECIPRDIKEHDSALAVLGMFNTLGFISKWRLSRPTLSRFILMIKRGYRDPPYHNWTHAFSVAHFIYLCITNLPLHGQLLPIELLALFVASLCHDIDHRGTNNSFQVTSKSVLAALYSSEGSVLERHHFSQTICVLNSEGCNIFENFSRQDYHHVLDLIRDIILATDLAHHLRIISDQRKMIDT-FYDSNSNHHHVLLMDLLMTSADLSDQSKNWKNTRAVAQLIYEEFFSQGDMEKSIGQKPAEQMDRERAC-VPSLQMSFLDGIALPCFQLFADLYPLFGQKMIENITNNRKKWEKL--NEDI 2850
            + I+ +S LC+PI+       +A+  +I  +  ++    E  +++ H    TA +  +SVA    Q+ R L  QTE    +L V+   F  +  +  LL+ IM  AK L NA+RC++F VD++ KEL S +FD    I E+++  PV     EIR  + +G+AG+VA TGE+LNI DAY+ P F R VD  TGY TRNILC PI      V+GV Q+ NK+ G  FT  DE+  K F+V+C +++  + MY +++ ++   ++  E + YH     +  K LT    P  +  + +   F+  P   +E   A+ V  + N+ G   K       L RF + +++ YR  PYHNW HA +VAH +Y  +      G    +E   L +A LCHD+DHRG +NS+       LAALYS+  S +E+HHFSQT+ +L  EG NIF N +  +Y  VL++IR  I+ATDLA +        +++ T   D N+  H   ++ L+MT+ DL   +K W  TR  A  IY EF+++GD  K IG +P   MDR++   VP  Q+ F + +A+PC+   ++L+P     ++E    N  +WE++   ED+
Sbjct:  191 SGIRVHSVLCLPIL-------TAIGDLIAILELHRHLGREPFNLS-HQEVATANLAWASVAIHQVQVCRGLAKQTELNDFLLDVSKTYFDNIVAIDSLLEHIMIYAKNLVNADRCALFQVDHNNKELYSDLFD----IGEENEGKPVFRKTKEIRFSIEKGIAGQVARTGEVLNIPDAYADPRFNREVDLYTGYTTRNILCMPIVSRG-TVIGVVQMVNKLGGSAFTKTDENNFKMFAVFCALALHCANMYHRIRHSECIYRVTMEKLSYHSICTSEEWKTLTQLTLPSAIYKEIELFHFDIAP--FEELWPAIFVYMVHNSCG---KTSFELEKLCRFTMSVRKNYRRVPYHNWKHAVTVAHCMYAILQKTT--GIFTELERKGLLIACLCHDLDHRGYSNSYLQKFDHPLAALYST--STMEQHHFSQTVSILQ-EGHNIFSNLTSGEYEQVLEIIRKAIIATDLALYFGNRKQLAELLSTGALDLNNRAHRDRVIGLMMTACDLCSVTKLWPVTRLTANDIYAEFWAEGDEMKKIGMQPISMMDRDKKDEVPQGQVGFYNAVAIPCYTTLSELFPP-SVPLLEACRENLSQWERIVQGEDV 770

[Close]

BLAST of Phosphodiesterase vs. Ensembl Zebrafish
Match: pde10a (phosphodiesterase 10A [Source:ZFIN;Acc:ZDB-GENE-040426-1115])

HSP 1 Score: 332.798 bits (852), Expect = 4.976e-100
Identity = 211/578 (36.51%), Postives = 321/578 (55.54%), Query Frame = 1

Query: 1087 TNIKWNSFLCVPIINQSDGCVSALVCMINKIGSNQSFTAEDISITQHLFQYTAAVLTSSVAF---QMERRLKIQTET---MLQVAMNIFRKLGDLTGLLKEIMTEAKKLTNAERCSVFLVDNDTKELVSKVFDGLPTISEQSQ-HPV-----EIRIPVTQGVAGRVATTGEMLNIVDAYSHPLFYRGVDEETGYKTRNILCFPIKDENEKVVGVAQLCNKINGPCFTNYDEDIAKAFSVYCCISIMHSLMYKKVQDAQHRNKLANELMIYHMQVNEDTVKWLTSCGYPDLMDIKEDFNSFECIPRDIKEHDSALAVLGMFNTLGFISKWRLSRPTLSRFILMIKRGYRDPPYHNWTHAFSVAHFIYLCITNLPLHGQLLPIELLALFVASLCHDIDHRGTNNSFQVTSKSVLAALYSSEGSVLERHHFSQTICVLNSEGCNIFENFSRQDYHHVLDLIRDIILATDLAHHLRIISDQRKMIDT-FYDSNSNHHHVLLMDLLMTSADLSDQSKNWKNTRAVAQLIYEEFFSQGDMEKSIGQKPAEQMDRERA-CVPSLQMSFLDGIALPCFQLFADLYP 2778
            + I+ +S LC+PI+       +A+  +I  +  ++    E  +++ H    TA +  +SVA    Q+ R L  QTE    +L V+   F  +  +  LL+ IM  AK L NA+RC++F VD++ KEL S +FD    I E+++  PV     EIR  + +G+AG+VA TGE+LNI DAY+ P F R VD  TGY TRNILC PI      V+GV Q+ NK+ G  FT  DE+  K F+V+C +++  + MY +++ ++   ++  E + YH     +  K LT    P  +  + +   F+  P   +E   A+ V  + N+ G   K       L RF + +++ YR  PYHNW HA +VAH +Y  +      G    +E   L +A LCHD+DHRG +NS+       LAALYS+  S +E+HHFSQT+ +L  EG NIF N +  +Y  VL++IR  I+ATDLA +        +++ T   D N+  H   ++ L+MT+ DL   +K W  TR  A  IY EF+++GD  K IG +P   MDR++   VP  Q+ F + +A+PC+   ++L+P
Sbjct:  191 SGIRVHSVLCLPIL-------TAIGDLIAILELHRHLGREPFNLS-HQEVATANLAWASVAIHQVQVCRGLAKQTELNDFLLDVSKTYFDNIVAIDSLLEHIMIYAKNLVNADRCALFQVDHNNKELYSDLFD----IGEENEGKPVFRKTKEIRFSIEKGIAGQVARTGEVLNIPDAYADPRFNREVDLYTGYTTRNILCMPIVSRG-TVIGVVQMVNKLGGSAFTKTDENNFKMFAVFCALALHCANMYHRIRHSECIYRVTMEKLSYHSICTSEEWKTLTQLTLPSAIYKEIELFHFDIAP--FEELWPAIFVYMVHNSCG---KTSFELEKLCRFTMSVRKNYRRVPYHNWKHAVTVAHCMYAILQKTT--GIFTELERKGLLIACLCHDLDHRGYSNSYLQKFDHPLAALYST--STMEQHHFSQTVSILQLEGHNIFSNLTSGEYEQVLEIIRKAIIATDLALYFGNRKQLAELLSTGALDLNNRAHRDRVIGLMMTACDLCSVTKLWPVTRLTANDIYAEFWAEGDEMKKIGMQPISMMDRDKKDEVPQGQVGFYNAVAIPCYTTLSELFP 746

[Close]

BLAST of Phosphodiesterase vs. Ensembl Zebrafish
Match: pde10a (phosphodiesterase 10A [Source:ZFIN;Acc:ZDB-GENE-040426-1115])

HSP 1 Score: 334.724 bits (857), Expect = 7.347e-100
Identity = 217/604 (35.93%), Postives = 333/604 (55.13%), Query Frame = 1

Query: 1087 TNIKWNSFLCVPIINQSDGCVSALVCMINKIGSNQSFTAEDISITQHLFQYTAAVLTSSVAF---QMERRLKIQTET---MLQVAMNIFRKLGDLTGLLKEIMTEAKKLTNAERCSVFLVDNDTKELVSKVFDGLPTISEQSQ-HPV-----EIRIPVTQGVAGRVATTGEMLNIVDAYSHPLFYRGVDEETGYKTRNILCFPIKDENEKVVGVAQLCNKINGPCFTNYDEDIAKAFSVYCCISIMHSLMYKKVQDAQHRNKLANELMIYHMQVNEDTVKWLTSCGYPDLMDIKEDFNSFECIPRDIKEHDSALAVLGMFNTLGFISKWRLSRPTLSRFILMIKRGYRDPPYHNWTHAFSVAHFIYLCITNLPLHGQLLPIELLALFVASLCHDIDHRGTNNSFQVTSKSVLAALYSSEGSVLERHHFSQTICVLNSEGCNIFENFSRQDYHHVLDLIRDIILATDLAHHLRIISDQRKMIDT-FYDSNSNHHHVLLMDLLMTSADLSDQSKNWKNTRAVAQLIYEEFFSQGDMEKSIGQKPAEQMDRERAC-VPSLQMSFLDGIALPCFQLFADLYPLFGQKMIENITNNRKKWEKL--NEDI 2850
            + I+ +S LC+PI+       +A+  +I  +  ++    E  +++ H    TA +  +SVA    Q+ R L  QTE    +L V+   F  +  +  LL+ IM  AK L NA+RC++F VD++ KEL S +FD    I E+++  PV     EIR  + +G+AG+VA TGE+LNI DAY+ P F R VD  TGY TRNILC PI      V+GV Q+ NK+ G  FT  DE+  K F+V+C +++  + MY +++ ++   ++  E + YH     +  K LT    P  +  + +   F+  P   +E   A+ V  + N+ G   K       L RF + +++ YR  PYHNW HA +VAH +Y  +      G    +E   L +A LCHD+DHRG +NS+       LAALYS+  S +E+HHFSQT+ +L  EG NIF N +  +Y  VL++IR  I+ATDLA +        +++ T   D N+  H   ++ L+MT+ DL   +K W  TR  A  IY EF+++GD  K IG +P   MDR++   VP  Q+ F + +A+PC+   ++L+P     ++E    N  +WE++   ED+
Sbjct:  191 SGIRVHSVLCLPIL-------TAIGDLIAILELHRHLGREPFNLS-HQEVATANLAWASVAIHQVQVCRGLAKQTELNDFLLDVSKTYFDNIVAIDSLLEHIMIYAKNLVNADRCALFQVDHNNKELYSDLFD----IGEENEGKPVFRKTKEIRFSIEKGIAGQVARTGEVLNIPDAYADPRFNREVDLYTGYTTRNILCMPIVSRG-TVIGVVQMVNKLGGSAFTKTDENNFKMFAVFCALALHCANMYHRIRHSECIYRVTMEKLSYHSICTSEEWKTLTQLTLPSAIYKEIELFHFDIAP--FEELWPAIFVYMVHNSCG---KTSFELEKLCRFTMSVRKNYRRVPYHNWKHAVTVAHCMYAILQKTT--GIFTELERKGLLIACLCHDLDHRGYSNSYLQKFDHPLAALYST--STMEQHHFSQTVSILQ-EGHNIFSNLTSGEYEQVLEIIRKAIIATDLALYFGNRKQLAELLSTGALDLNNRAHRDRVIGLMMTACDLCSVTKLWPVTRLTANDIYAEFWAEGDEMKKIGMQPISMMDRDKKDEVPQGQVGFYNAVAIPCYTTLSELFPP-SVPLLEACRENLSQWERIVQGEDV 770

[Close]

BLAST of Phosphodiesterase vs. Ensembl Zebrafish
Match: pde11a (phosphodiesterase 11a [Source:ZFIN;Acc:ZDB-GENE-070912-207])

HSP 1 Score: 325.094 bits (832), Expect = 3.809e-96
Identity = 197/604 (32.62%), Postives = 325/604 (53.81%), Query Frame = 1

Query: 1069 NELELLTNIKWNSFLCVPIINQSDGCVSALVCMINKIGSNQSFTAEDISITQHLFQYTAAVLTSSVAFQMERRLKIQTETMLQVAMNIFRKLGDLTGLLKEIMTEAKKLTNAERCSVFLVDNDTKELV--SKVFDGL-PTISEQSQHPVEIRIP--------VTQGVAGRVATTGEMLNIVDAYSHPLFYRGVDEETGYKTRNILCFPIKDENEKVVGVAQLCNKINGPCFTNYDEDIAKAFSVYCCISIMHSLMYKKVQDAQHRNKLANELMIYHMQVNEDTVKWLTSCGYPDLMDIKEDFNSFECIPRDIKEHDSALAVLGMFNTLGFISKWRLSRPTLSRFILMIKRGYRDPPYHNWTHAFSVAHFIYLCITNLPLHGQLLPIELLALFVASLCHDIDHRGTNNSFQVTSKSVLAALYSSEGSVLERHHFSQTICVLNSEGCNIFENFSRQDYHHVLDLIRDIILATDLAHHLRIISDQRKMIDTFYDSNSNHHHVLLMDLLMTSADLSDQSKNWKNTRAVAQLIYEEFFSQGDMEKS-IGQKPAEQMDRERAC-VPSLQMSFLDGIALPCFQLFADLYPLFGQKMIENITNNRKKWEKLN 2841
            +E++ LT  K  S LC+PI N SDG V  +   INK  +   FT +D    +    +    ++++  F   R+   ++  +L+V  ++F +  DL  ++++IM  A+ L   ERCSV L+++    +V  +K F+ L P  S   ++  +  +         +   +A  VA+TG  +NI DAY  P F    D+ +G+  R++LC PI + N +++GVAQ+ N+++G  F + D+ + +AF ++C + I +++MY +V+ +  +  +A +++ YH   ++  V    +   P + ++  D  SF+    D+       A L MF  LG + K+++   TL R++L +++ YR   YHNW HAF+V   ++  +T       L  +E LAL V  +CHD+DHRGTNN+FQ  + S L+ LY +  + LE HHF+  + +L SEG NIF N S  +Y  ++ L++  ILATDL               T Y             +LMT+ DL   +K W+ +  VA+L+  EFF QGD E+S +   P+   DR R   +P LQ+ ++DGI  P ++ FA L P   Q M++ I  NR KWE+L+
Sbjct:  260 DEIDKLTGYKTKSLLCMPIHN-SDGEVIGVAQAINKSPNGALFTQDD---EKMYLPFCGIAISNAQLFAASRKEYDRSRALLEVVNDLFEEQTDLEKIVRKIMHRAQTLLKCERCSVQLLEDIESPVVKFTKSFELLSPKCSADMENSFKDSMDKSSYSDWLINNSIAELVASTGLPVNISDAYQDPRFDAEADQFSGFHIRSVLCVPIWNSNHQIIGVAQVLNRLDGKPFDDADQRLFEAFVIFCGLGINNTIMYDQVKKSWAKQSVALDVLSYHATCSKTEVDKFKAANIPLVCELGIDKLSFDDFSLDVDAM--VTAALRMFMELGMVQKFKIDYETLCRWLLTVRKNYRMVLYHNWRHAFNVCQCMFSMLTTAGFQETLTEMETLALIVGCICHDLDHRGTNNAFQAKTGSALSLLYGTSAT-LEHHHFNHAVMILQSEGHNIFSNLSSHEYGELMQLLKQSILATDL---------------TLY----------FQSMLMTACDLGAVTKPWEISHKVAELVTSEFFEQGDRERSELKLTPSAIFDRNRKDELPGLQLEWIDGICAPLYETFAKLNPKL-QPMMDLIKANRAKWEELH 830

HSP 2 Score: 105.145 bits (261), Expect = 1.808e-22
Identity = 69/189 (36.51%), Postives = 107/189 (56.61%), Query Frame = 1

Query: 1297 QTETMLQVAMNIFRKLGDLTGLLKEIMTEAKKLTNAERCSVFLVDNDT--KELVSKVFDG------LPTISEQSQHPVEIRIPVTQGVAGRVATTGEMLNIVDAYSHPLFYRGVDEETGYKTRNILCFPIKDENEKVVGVAQLCNK-INGPCFTNYDEDIAKAFSVYCCISIMHSLMYKKVQDAQHRNK 1836
            + E  L++  +I   L DLT L  +I+     + +A+RCS+FLV+  T  K LVSK FD       LP++S       E+++P  +G+ G VA  GE +NI DAY    F   +D+ TGYKT+++LC PI + + +V+GVAQ  NK  NG  FT  DE   K +  +C I+I ++ ++   +    R++
Sbjct:  154 EREFFLELVKDISNDL-DLTSLSYKILVFVCIMVDADRCSLFLVEGPTNKKTLVSKFFDVHAGTTVLPSLSNSD----EVQVPWGKGIIGYVAEHGETVNIPDAYQDHRFSDEIDKLTGYKTKSLLCMPIHNSDGEVIGVAQAINKSPNGALFTQDDE---KMYLPFCGIAISNAQLFAASRKEYDRSR 334

[Close]

BLAST of Phosphodiesterase vs. Ensembl Xenopus
Match: pde2a (phosphodiesterase 2A [Source:NCBI gene;Acc:780063])

HSP 1 Score: 349.747 bits (896), Expect = 4.374e-108
Identity = 203/564 (35.99%), Postives = 328/564 (58.16%), Query Frame = 1

Query:  253 MKRKLSESCLENTERELLLGLSNIVSYEEIPDAVKTTINRVFPNSNSVRLEWINTR-----ENSTKSIRSNGWMNE----NKIIPQSSLIINRKDRLQEQYSDYFDSENSDNFGIIVPLISSEMKEFQAFLSFSCQEFNQNEKKLLQTFENQVKVMFQRLERLKN----------SKDSNLQQSNLQDTKLDSSDFY--IDSTILSLCADLHDRDPGILQVKIIRFLKQRIHMESAFILTISNNNLELVCQAQDEQIFDPEKRFRVTDSIFERIMKEKICAQLSDVNMFQDKLNELELLTNIKWNSFLCVPIINQSDGCVSALVCMINKIGSNQSFTAEDISITQHLFQYTAAVLTSSVAFQMERRLKIQTETMLQVAMNIFRKLGDLTGLLKEIMTEAKKLTNAERCSVFLVDNDTKELVSKVFDGLPTISEQSQHPVEIRIPVTQGVAGRVATTGEMLNIVDAYSHPLFYRGVDEETGYKTRNILCFPIKDENEKVVGVAQLCNKINGPCFTNYDEDIAKAFSVYCCISIMHSLMYKKVQDAQHRNKLANELMIYHMQVNED 1881
            +K + S S      ++ LL L +I+    + DA++  I  V P  ++  +  ++       ++    +   G + +     K I  S L     + L +Q S        D   +I+PL+  +     + +   C + + ++++ L+T E    V  +R+  ++                  Q++L      +++ Y  +D  IL LC +L+D D   LQ+K+I +L+Q+       +L +S ++ +L CQ    ++ + E  F +T     +++ +K    L D++   ++  +L  +   + +S LCVP+I+++   V AL C  NK G    +T  D    QH F YT+ VLTS++AFQ E++LK + +++ +V  ++   L D++ LL+EI+TEA+ L+NAE CSVFL++  + ELV+KVFDG   + ++S    EIRIP  QG+AG VATTG++LNI DAYSHPLFYRGVD+ TG++TRNILCFPIK+E+ +V+GVA+L NKINGP FT +DED+A AFS+YC ISI HSL+YK+V++AQ R+ LANE+M+YHM++  D
Sbjct:   30 LKAEDSPSLGSEALQDALLTLGSIIDIPRLRDAIRDAIASVLPKVDNAFIYLLDAEGRLVCDDPPHELPPEGKLRDAVLLQKRIECSGL--TPSELLGQQMSSLAAPLPPDKQVLILPLLDQDTARVVSVILLHCSQLSDSDEQNLRTLEKHTLVACKRVLAIQKLQPSPQVPPSPLSPRTYQNSLPKPSPTANESYDELDRKILQLCGELYDLDAASLQIKVIHYLEQQTQSPCCCLLLVSEDSHQLFCQVVGGKVLEEEISFPLTFGHLGQVVDKKKSITLQDIS--SEEHRQLNNMLGFEVHSMLCVPVISRATSQVVALACAFNKQGGK--YTEVDEHKIQHCFCYTSTVLTSTLAFQKEQKLKCECQSLRRVRKSLITYLDDVSVLLQEIITEARNLSNAEICSVFLLERQSHELVAKVFDG-GVVDDES---YEIRIPADQGIAGHVATTGQILNIKDAYSHPLFYRGVDDSTGFRTRNILCFPIKNESNEVIGVAELVNKINGPGFTKFDEDLATAFSIYCGISIAHSLLYKQVREAQFRSHLANEMMMYHMKICRD 583

[Close]

BLAST of Phosphodiesterase vs. Ensembl Xenopus
Match: pde2a (phosphodiesterase 2A [Source:NCBI gene;Acc:780063])

HSP 1 Score: 338.191 bits (866), Expect = 1.316e-103
Identity = 201/561 (35.83%), Postives = 320/561 (57.04%), Query Frame = 1

Query:  253 MKRKLSESCLENTERELLLGLSNIVSYEEIPDAVKTTINRVFPNSNSVRLEWINTR-----ENSTKSIRSNGWMNE----NKIIPQSSLIINRKDRLQEQYSDYFDSENSDNFGIIVPLISSEMKEFQAFLSFSCQEFNQNEKKLLQTFENQVKVMFQRLERLKN----------SKDSNLQQSNLQDTKLDSSDFY--IDSTILSLCADLHDRDPGILQVKIIRFLKQRIHMESAFILTISNNNLELVCQAQDEQIFDPEKRFRVTDSIFERIMKEKICAQLSDVNMFQDKLNELELLTNIKWNSFLCVPIINQSDGCVSALVCMINKIGSNQSFTAEDISITQHLFQYTAAVLTSSVAFQMERRLKIQTETMLQVAMNIFRKLGDLTGLLKEIMTEAKKLTNAERCSVFLVDNDTKELVSKVFDGLPTISEQSQHPVEIRIPVTQGVAGRVATTGEMLNIVDAYSHPLFYRGVDEETGYKTRNILCFPIKDENEKVVGVAQLCNKINGPCFTNYDEDIAKAFSVYCCISIMHSLMYKKVQDAQHRNKLANELMIYHMQV 1872
            +K + S S      ++ LL L +I+    + DA++  I  V P  ++  +  ++       ++    +   G + +     K I  S L     + L +Q S        D   +I+PL+  +     + +   C + + ++++ L+T E    V  +R+  ++                  Q++L      +++ Y  +D  IL LC +L+D D   LQ+K+I +L+Q+       +L +S ++ +L CQ    ++ + E  F +T     +++ +K    L D++   ++  +L  +   + +S LCVP+I+++   V AL C  NK G    +T  D    QH F YT+ VLTS++AFQ E++LK + +              D++ LL+EI+TEA+ L+NAE CSVFL++  + ELV+KVFDG   + ++S    EIRIP  QG+AG VATTG++LNI DAYSHPLFYRGVD+ TG++TRNILCFPIK+E+ +V+GVA+L NKINGP FT +DED+A AFS+YC ISI HSL+YK+V++AQ R+ LANE+M+YHM+V
Sbjct:   28 LKAEDSPSLGSEALQDALLTLGSIIDIPRLRDAIRDAIASVLPKVDNAFIYLLDAEGRLVCDDPPHELPPEGKLRDAVLLQKRIECSGL--TPSELLGQQMSSLAAPLPPDKQVLILPLLDQDTARVVSVILLHCSQLSDSDEQNLRTLEKHTLVACKRVLAIQKLQPSPQVPPSPLSPRTYQNSLPKPSPTANESYDELDRKILQLCGELYDLDAASLQIKVIHYLEQQTQSPCCCLLLVSEDSHQLFCQVVGGKVLEEEISFPLTFGHLGQVVDKKKSITLQDIS--SEEHRQLNNMLGFEVHSMLCVPVISRATSQVVALACAFNKQGGK--YTEVDEHKIQHCFCYTSTVLTSTLAFQKEQKLKCECQV---------GPTDDVSVLLQEIITEARNLSNAEICSVFLLERQSHELVAKVFDG-GVVDDES---YEIRIPADQGIAGHVATTGQILNIKDAYSHPLFYRGVDDSTGFRTRNILCFPIKNESNEVIGVAELVNKINGPGFTKFDEDLATAFSIYCGISIAHSLLYKQVREAQFRSHLANEMMMYHMKV 569

[Close]

BLAST of Phosphodiesterase vs. Ensembl Xenopus
Match: ENSXETT00000053056.1 (phosphodiesterase 11A [Source:NCBI gene;Acc:100379882])

HSP 1 Score: 343.584 bits (880), Expect = 1.871e-102
Identity = 205/629 (32.59%), Postives = 345/629 (54.85%), Query Frame = 1

Query: 1048 NMFQDKL--NELELLTNIKWNSFLCVPIINQSDGCVSALVCMINKIGSNQSFTAEDISITQHLFQYTAAVLTSSVAFQMERRLKIQTETMLQVAMNIFRKLGDLTGLLKEIMTEAKKLTNAERCSVFLVDNDTKELV--SKVFDGL-PTISEQSQHPVEIRIP--------VTQGVAGRVATTGEMLNIVDAYSHPLFYRGVDEETGYKTRNILCFPIKDENEKVVGVAQLCNKINGPCFTNYDEDIAKAFSVYCCISIMHSLMYKKVQDAQHRNKLANELMIYHMQVNEDTVKWLTSCGYPDLMDIKEDFNSFECIPRDIKEHDSALAVLGMFNTLGFISKWRLSRPTLSRFILMIKRGYRDPPYHNWTHAFSVAHFIYLCITNLPLHGQLLPIELLALFVASLCHDIDHRGTNNSFQVTSKSVLAALYSSEGSVLERHHFSQTICVLNSEGCNIFENFSRQDYHHVLDLIRDIILATDLAHHLRIISDQRKMIDTF-YDSNSNHHHVLLMDLLMTSADLSDQSKNWKNTRAVAQLIYEEFFSQGDMEK-SIGQKPAEQMDRERAC-VPSLQMSFLDGIALPCFQLFADLYPLFG--QKMIENITNNRKKWEKLNEDIKNGKISANIF 2880
            + +QD+   +E++ LT  K  S LC+PI   SDG +  +   INK      F  +D  + Q    +    ++++  F   R+   ++  +L+V  ++F +  DL  ++K+IM  A+ L   ERCSV L+++    +V  +K F+ L P  S  +++  +  +         V   +A  VA+TG  +NI DAY  P F    D+ +G+  R++LC PI + + +++GVAQ+ N+I+G  F + D+ + +AF ++C + I +++MY +V+ +  +  +A +++ YH   ++  V    +   P + ++      F+    D+    SA   L MF  LG + K+++   TL R++L I++ YR   YHNW HAF+V   ++  +T       L   E LAL V  LCHD+DHRGTNN+FQ  S S L+ LY +  + LE HHF+  + +L SEG NIF N S Q+Y  ++ L++  ILATD+  H    ++  ++++   Y+ N   H V+   +LMT+ DL   +K W+ +R VA+L+  EFF QGD E+  +   P+   DR R   +P LQ+ ++D I   CF L+  L  + G  + M++++T NR KWE+L+   K G  S+  +
Sbjct:  256 DAYQDRRFSDEIDKLTGYKTKSLLCMPI-RSSDGEIIGVAQAINKTPGGAPFIEDDEKVMQMYLPFCGIAISNAQLFAASRKEYDRSRALLEVVNDLFEEQTDLEKVVKKIMHRAQNLLKCERCSVLLLEDIESPVVKFTKSFELLSPKCSADTENSFKDSVEKSSYSDWLVNNSIAELVASTGLPVNISDAYQDPRFDVEADQFSGFHIRSVLCVPIWNSSHQIIGVAQVLNRIDGKPFDDADQRLFEAFVIFCGLGINNTIMYDQVKKSWAKQSVALDVLSYHATCSKAEVDKFKAANIPLVSELSIADIHFDDFCLDVDAMISA--ALRMFMELGMVQKFKIDYETLCRWLLTIRKNYRMVLYHNWRHAFNVCQLMFAMLTTAGFQEVLSDTETLALIVGCLCHDLDHRGTNNAFQAKSGSALSQLYGTSAT-LEHHHFNHAVMILQSEGHNIFANLSSQEYSDLMQLLKQSILATDITLHFERRNEFFELVNKGDYNWNVKSHRVIFRSMLMTACDLGAATKPWEISRQVAELVTSEFFEQGDRERLELKMTPSAIFDRNRKDELPRLQLEWIDNI---CFPLYESLVKINGKLKPMLDSVTTNRGKWEELHR--KQGNSSSTSY 875

HSP 2 Score: 103.219 bits (256), Expect = 1.085e-21
Identity = 60/178 (33.71%), Postives = 103/178 (57.87%), Query Frame = 1

Query: 1348 DLTGLLKEIMTEAKKLTNAERCSVFLVDN--DTKELVSKVFDG------LPTISEQSQHPVEIRIPVTQGVAGRVATTGEMLNIVDAYSHPLFYRGVDEETGYKTRNILCFPIKDENEKVVGVAQLCNKI-NGPCFTNYDEDIAKAFSVYCCISIMHSLMYKKVQDAQHRNKLANELM 1854
            +LT L  +I+     + +A+RCS+FLV+   + K LVSK FD       LP+ S ++ +  E+++P  +G+ G VA  GE +NI DAY    F   +D+ TGYKT+++LC PI+  + +++GVAQ  NK   G  F   DE + + +  +C I+I ++ ++   +    R++   E++
Sbjct:  173 NLTSLCYKILIFVCIMVDADRCSLFLVEGTANKKSLVSKFFDVHAGTTLLPSCSTENSN--EVQVPWGKGIIGYVAEHGETVNIPDAYQDRRFSDEIDKLTGYKTKSLLCMPIRSSDGEIIGVAQAINKTPGGAPFIEDDEKVMQMYLPFCGIAISNAQLFAASRKEYDRSRALLEVV 348

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BLAST of Phosphodiesterase vs. Ensembl Xenopus
Match: PDE10A (phosphodiesterase 10A [Source:NCBI gene;Acc:100485841])

HSP 1 Score: 323.168 bits (827), Expect = 7.116e-96
Identity = 203/552 (36.78%), Postives = 308/552 (55.80%), Query Frame = 1

Query: 1240 TAAVLTSSVAF---QMERRLKIQTET---MLQVAMNIFRKLGDLTGLLKEIMTEAKKLTNAERCSVFLVDNDTKELVSKVFDGLPTISEQSQ-HPV-----EIRIPVTQGVAGRVATTGEMLNIVDAYSHPLFYRGVDEETGYKTRNILCFPIKDENEKVVGVAQLCNKINGPCFTNYDEDIAKAFSVYCCISIMHSLMYKKVQDAQHRNKLANELMIYHMQVNEDTVKWLTSCGYPDLMDIKEDFNSFECIPRDIKEHDSALAVLGMFNTLGFISKWRLSRPTLSRFILMIKRGYRDPPYHNWTHAFSVAHFIYLCITNLPLHGQLLPIELLALFVASLCHDIDHRGTNNSFQVTSKSVLAALYSSEGSVLERHHFSQTICVLNSEGCNIFENFSRQDYHHVLDLIRDIILATDLAHHLRIISDQRKMIDTFY-----DSNSNHHHVLLMDLLMTSADLSDQSKNWKNTRAVAQLIYEEFFSQGDMEKSIGQKPAEQMDRERAC-VPSLQMSFLDGIALPCFQLFADLYPLFGQKMIENITNNRKKWEKLN 2841
            TA +  +SVA    Q+ R L  QTE    +L V+   F  +  +  LL+ IM  AK L NA+RC++F VD+  KEL S +FD    I E+ +  PV     EIR  + +G+AG+VA TGE+LNI DAY+ P F R VD  TGY TRNILC PI      V+GV Q+ NK++G  F+  DE+  K F+V+C +++  + MY +++ ++   ++  E + YH     D  + L +C  P  +  + +   F+  P   ++   A+ V  +  + G   K       L RF + +K+ YR  PYHNW HA +V+H +Y+ + N         +E   L VA LCHD+DHRG  NS+       LAALYS+  S +E+HHFSQT+ +L  EG NIF N S  +Y  VL++IR  I+ATDLA +       RK ++  +     + N+  H   L+ L+MT+ DL   +K W  TR +A  IY EF+++GD  K +G  P   MDR++   +P  QM F + +A+PC+   ++++P   + +++    N  +WEK++
Sbjct:  232 TANLAWASVAIHQVQVCRGLAKQTELNDFLLDVSKTYFDNIVAIDSLLEHIMIYAKNLVNADRCALFQVDHKNKELYSDLFD----IGEEDEGKPVFKKTKEIRFSIEKGIAGQVARTGEVLNIPDAYADPRFNREVDVYTGYTTRNILCMPIVIRG-SVIGVVQMVNKLSGSAFSKTDENNFKMFAVFCALALHCANMYHRIRHSECIYRVTLEKLSYHSICTSDEWQNLMNCTLPVSLCREIELYHFDIQP--FEDLWPAIYVYMIHQSCG---KNCFELEKLCRFTMSVKKNYRRVPYHNWKHAVTVSHCMYVILQN--NQEIFTDLERKGLLVACLCHDLDHRGYTNSYLQKFDHPLAALYST--STMEQHHFSQTVSILQLEGHNIFSNLSSNEYEQVLEIIRKAIIATDLALYF----GNRKHLEDLHQMGALNLNNQAHRDRLIGLMMTACDLCSVTKLWPVTRLIADDIYAEFWTEGDEMKRLGISPIPMMDRDKQDEIPQGQMGFYNAVAVPCYTTLSEIFP-STRPLLQACKENLSQWEKVS 764

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BLAST of Phosphodiesterase vs. Ensembl Xenopus
Match: PDE10A (phosphodiesterase 10A [Source:NCBI gene;Acc:100485841])

HSP 1 Score: 303.138 bits (775), Expect = 1.481e-89
Identity = 181/477 (37.95%), Postives = 271/477 (56.81%), Query Frame = 1

Query: 1384 AKKLTNAERCSVFLVDNDTKELVSKVFDGLPTISEQSQ-HPV-----EIRIPVTQGVAGRVATTGEMLNIVDAYSHPLFYRGVDEETGYKTRNILCFPIKDENEKVVGVAQLCNKINGPCFTNYDEDIAKAFSVYCCISIMHSLMYKKVQDAQHRNKLANELMIYHMQVNEDTVKWLTSCGYPDLMDIKEDFNSFECIPRDIKEHDSALAVLGMFNTLGFISKWRLSRPTLSRFILMIKRGYRDPPYHNWTHAFSVAHFIYLCITNLPLHGQLLPIELLALFVASLCHDIDHRGTNNSFQVTSKSVLAALYSSEGSVLERHHFSQTICVLNSEGCNIFENFSRQDYHHVLDLIRDIILATDLAHHLRIISDQRKMIDTFY-----DSNSNHHHVLLMDLLMTSADLSDQSKNWKNTRAVAQLIYEEFFSQGDMEKSIGQKPAEQMDRERAC-VPSLQMSFLDGIALPCFQLFADLYP 2778
            AK L NA+RC++F VD+  KEL S +FD    I E+ +  PV     EIR  + +G+AG+VA TGE+LNI DAY+ P F R VD  TGY TRNILC PI      V+GV Q+ NK++G  F+  DE+  K F+V+C +++  + MY +++ ++   ++  E + YH     D  + L +C  P  +  + +   F+  P   ++   A+ V  +  + G   K       L RF + +K+ YR  PYHNW HA +V+H +Y+ + N         +E   L VA LCHD+DHRG  NS+       LAALYS+  S +E+HHFSQT+ +L  EG NIF N S  +Y  VL++IR  I+ATDLA +       RK ++  +     + N+  H   L+ L+MT+ DL   +K W  TR +A  IY EF+++GD  K +G  P   MDR++   +P  QM F + +A+PC+   ++++P
Sbjct:  220 AKNLVNADRCALFQVDHKNKELYSDLFD----IGEEDEGKPVFKKTKEIRFSIEKGIAGQVARTGEVLNIPDAYADPRFNREVDVYTGYTTRNILCMPIVIRG-SVIGVVQMVNKLSGSAFSKTDENNFKMFAVFCALALHCANMYHRIRHSECIYRVTLEKLSYHSICTSDEWQNLMNCTLPVSLCREIELYHFDIQP--FEDLWPAIYVYMIHQSCG---KNCFELEKLCRFTMSVKKNYRRVPYHNWKHAVTVSHCMYVILQN--NQEIFTDLERKGLLVACLCHDLDHRGYTNSYLQKFDHPLAALYST--STMEQHHFSQTVSILQLEGHNIFSNLSSNEYEQVLEIIRKAIIATDLALYF----GNRKHLEDLHQMGALNLNNQAHRDRLIGLMMTACDLCSVTKLWPVTRLIADDIYAEFWTEGDEMKRLGISPIPMMDRDKQDEIPQGQMGFYNAVAVPCYTTLSEIFP 678

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BLAST of Phosphodiesterase vs. Ensembl Mouse
Match: Pde2a (phosphodiesterase 2A, cGMP-stimulated [Source:MGI Symbol;Acc:MGI:2446107])

HSP 1 Score: 783.097 bits (2021), Expect = 0.000e+0
Identity = 393/863 (45.54%), Postives = 570/863 (66.05%), Query Frame = 1

Query:  295 RELLLGLSNIVSYEEIPDAVKTTINRVFPNSNSVRLEWINTR-----ENSTKSIRSNGWMNENKIIPQSSLIINR---KDRLQEQYSDYFDSENSDNFGIIVPLISSEMKEFQAFLSFSCQEFNQNEKKLLQTFENQVKVMFQRLERLKNSKDSNLQQSNL---QDTKLDSSDFYIDSTILSLCADLHDRDPGILQVKIIRFLKQRIHMESAFILTISNNNLELVCQAQDEQIFDPEKRFRVTDSIFERIMKEKICAQLSDVNMFQDKLNELELLTNIKWNSFLCVPIINQSDGCVSALVCMINKIGSN---QSFTAEDISITQHLFQYTAAVLTSSVAFQMERRLKIQTETMLQVAMNIFRKLGDLTGLLKEIMTEAKKLTNAERCSVFLVDNDTKELVSKVFDGLPTISEQSQHPVEIRIPVTQGVAGRVATTGEMLNIVDAYSHPLFYRGVDEETGYKTRNILCFPIKDENEKVVGVAQLCNKINGPCFTNYDEDIAKAFSVYCCISIMHSLMYKKVQDAQHRNKLANELMIYHMQVNEDTVKWLTSCGYPDLMDIKEDFNSFECIPRDIKEHDSALAVLGMFNTLGFISKWRLSRPTLSRFILMIKRGYRDPPYHNWTHAFSVAHFIYLCITNLPLHGQLLPIELLALFVASLCHDIDHRGTNNSFQVTSKSVLAALYSSEGSVLERHHFSQTICVLNSEGCNIFENFSRQDYHHVLDLIRDIILATDLAHHLRIISDQRKMIDTFYDSNSNHHHVLLMDLLMTSADLSDQSKNWKNTRAVAQLIYEEFFSQGDMEKSIGQKPAEQMDRERACVPSLQMSFLDGIALPCFQLFADLYPLFGQKMIENITNNRKKWEKLN 2841
            ++ LL L  ++    +  A +  ++ V P   +V    ++       E+    +   G + E  +I Q  L  N     D L +  +        D   +++PL+  E     A +   C + + +E++ LQ  E    V  +R++ L+  +   +Q +++   +D K +      D  IL LC +L D D   LQ+K++++L+Q        +L +S +NL+L C+   +++   E  F +T     +++++K C QL D+    D + +L+ +   +  + LCVP+I+++   V AL C  NK+G +    SFT ED  + QH F YT  VLTS++AFQ E++LK + + +LQVA N+F  L D++ LL+EI+TEA+ L+NAE CSVFL+D +  ELV+KVFDG   + ++S    EIRIP  QG+AG VATTG++LNI DAY+HPLFYRGVD+ TG++TRNILCFPIK+EN++V+GVA+L NKINGP F+ +DED+A AFS+YC ISI HSL+YKKV +AQ+R+ LANE+M+YHM+V++D    L   G   +  I  +F +F   PR + E D+++A+L M   + FI+ +++  PTL+RF LM+K+GYRDPPYHNW HAFSV+HF YL   NL L   L  IE+ ALF++ +CHD+DHRGTNNSFQV SKSVLAALYSSEGSV+ERHHF+Q I +LN+ GCNIF++FSR+DY  +LDL+RDIILATDLAHHLRI  D +KM +  YD N+  HH LL+ LLMTS DLSDQ+K WK TR +A+LIY+EFFSQGD+EK++G +P E MDRE+A +P LQ+SF++ IA+P ++L  DL+P    ++ E + +NR+ W K++
Sbjct:   46 QDALLSLGAVIDIAGLRQAARDALSAVLPKVETVYTYLLDGESRLVCEDPPHELPQEGKIRE-AVISQKRLSCNGLGPSDLLGKPLARLVAPLAPDMQVLVIPLLDKETGSVAAVILVHCGQLSDSEEQSLQVVEKHALVALRRVQALQQRRPEAVQNTSVDASEDQKDEKGYTDHDRKILQLCGELFDLDATSLQLKVLQYLQQETQATHCCLLLVSEDNLQLSCKVIGDKVLGEEVSFPLTMGRLGQVVEDKQCIQLKDLT--SDDVQQLQNMLGCELQAMLCVPVISRATDQVVALACAFNKLGGDFPTSSFTDEDEHVIQHCFHYTGTVLTSTLAFQKEQKLKCECQALLQVAKNLFTHLDDVSVLLQEIITEARNLSNAEICSVFLLDQN--ELVAKVFDG-GVVDDES---YEIRIPADQGIAGHVATTGQILNIPDAYAHPLFYRGVDDSTGFRTRNILCFPIKNENQEVIGVAELVNKINGPWFSKFDEDLATAFSIYCGISIAHSLLYKKVNEAQYRSHLANEMMMYHMKVSDDEYTKLLHDGIQPVAAIDSNFANFTYTPRSLPEDDTSMAILSMLQDMNFINNYKIDCPTLARFCLMVKKGYRDPPYHNWMHAFSVSHFCYLLYKNLELSNYLEDIEIFALFISCMCHDLDHRGTNNSFQVASKSVLAALYSSEGSVMERHHFAQAIAILNTHGCNIFDHFSRKDYQRMLDLMRDIILATDLAHHLRIFKDLQKMAEVGYDRNNRQHHRLLLCLLMTSCDLSDQTKGWKTTRKIAELIYKEFFSQGDLEKAMGNRPMEMMDREKAYIPELQISFMEHIAMPIYKLLQDLFPK-AAELYERVASNREHWTKVS 898

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BLAST of Phosphodiesterase vs. Ensembl Mouse
Match: Gm45837 (predicted gene 45837 [Source:MGI Symbol;Acc:MGI:5804952])

HSP 1 Score: 781.941 bits (2018), Expect = 0.000e+0
Identity = 392/857 (45.74%), Postives = 567/857 (66.16%), Query Frame = 1

Query:  304 LLGLSNIVSYEEIPDAVKTTINRVFPNSNSVRLEWINTR-----ENSTKSIRSNGWMNENKIIPQSSLIINR---KDRLQEQYSDYFDSENSDNFGIIVPLISSEMKEFQAFLSFSCQEFNQNEKKLLQTFENQVKVMFQRLERLKNSKDSNLQQSNL---QDTKLDSSDFYIDSTILSLCADLHDRDPGILQVKIIRFLKQRIHMESAFILTISNNNLELVCQAQDEQIFDPEKRFRVTDSIFERIMKEKICAQLSDVNMFQDKLNELELLTNIKWNSFLCVPIINQSDGCVSALVCMINKIGSNQSFTAEDISITQHLFQYTAAVLTSSVAFQMERRLKIQTETMLQVAMNIFRKLGDLTGLLKEIMTEAKKLTNAERCSVFLVDNDTKELVSKVFDGLPTISEQSQHPVEIRIPVTQGVAGRVATTGEMLNIVDAYSHPLFYRGVDEETGYKTRNILCFPIKDENEKVVGVAQLCNKINGPCFTNYDEDIAKAFSVYCCISIMHSLMYKKVQDAQHRNKLANELMIYHMQVNEDTVKWLTSCGYPDLMDIKEDFNSFECIPRDIKEHDSALAVLGMFNTLGFISKWRLSRPTLSRFILMIKRGYRDPPYHNWTHAFSVAHFIYLCITNLPLHGQLLPIELLALFVASLCHDIDHRGTNNSFQVTSKSVLAALYSSEGSVLERHHFSQTICVLNSEGCNIFENFSRQDYHHVLDLIRDIILATDLAHHLRIISDQRKMIDTFYDSNSNHHHVLLMDLLMTSADLSDQSKNWKNTRAVAQLIYEEFFSQGDMEKSIGQKPAEQMDRERACVPSLQMSFLDGIALPCFQLFADLYPLFGQKMIENITNNRKKWEKLN 2841
            LL L  ++    +  A +  ++ V P   +V    ++       E+    +   G + E  +I Q  L  N     D L +  +        D   +++PL+  E     A +   C + + +E++ LQ  E    V  +R++ L+  +   +Q +++   +D K +      D  IL LC +L D D   LQ+K++++L+Q        +L +S +NL+L C+   +++   E  F +T     +++++K C QL D+    D + +L+ +   +  + LCVP+I+++   V AL C  NK+G +  FT ED  + QH F YT  VLTS++AFQ E++LK + + +LQVA N+F  L D++ LL+EI+TEA+ L+NAE CSVFL+D +  ELV+KVFDG   + ++S    EIRIP  QG+AG VATTG++LNI DAY+HPLFYRGVD+ TG++TRNILCFPIK+EN++V+GVA+L NKINGP F+ +DED+A AFS+YC ISI HSL+YKKV +AQ+R+ LANE+M+YHM+V++D    L   G   +  I  +F +F   PR + E D+++A+L M   + FI+ +++  PTL+RF LM+K+GYRDPPYHNW HAFSV+HF YL   NL L   L  IE+ ALF++ +CHD+DHRGTNNSFQV SKSVLAALYSSEGSV+ERHHF+Q I +LN+ GCNIF++FSR+DY  +LDL+RDIILATDLAHHLRI  D +KM +  YD N+  HH LL+ LLMTS DLSDQ+K WK TR +A+LIY+EFFSQGD+EK++G +P E MDRE+A +P LQ+SF++ IA+P ++L  DL+P    ++ E + +NR+ W K++
Sbjct:   75 LLSLGAVIDIAGLRQAARDALSAVLPKVETVYTYLLDGESRLVCEDPPHELPQEGKIRE-AVISQKRLSCNGLGPSDLLGKPLARLVAPLAPDMQVLVIPLLDKETGSVAAVILVHCGQLSDSEEQSLQVVEKHALVALRRVQALQQRRPEAVQNTSVDASEDQKDEKGYTDHDRKILQLCGELFDLDATSLQLKVLQYLQQETQATHCCLLLVSEDNLQLSCKVIGDKVLGEEVSFPLTMGRLGQVVEDKQCIQLKDLT--SDDVQQLQNMLGCELQAMLCVPVISRATDQVVALACAFNKLGGD-FFTDEDEHVIQHCFHYTGTVLTSTLAFQKEQKLKCECQALLQVAKNLFTHLDDVSVLLQEIITEARNLSNAEICSVFLLDQN--ELVAKVFDG-GVVDDES---YEIRIPADQGIAGHVATTGQILNIPDAYAHPLFYRGVDDSTGFRTRNILCFPIKNENQEVIGVAELVNKINGPWFSKFDEDLATAFSIYCGISIAHSLLYKKVNEAQYRSHLANEMMMYHMKVSDDEYTKLLHDGIQPVAAIDSNFANFTYTPRSLPEDDTSMAILSMLQDMNFINNYKIDCPTLARFCLMVKKGYRDPPYHNWMHAFSVSHFCYLLYKNLELSNYLEDIEIFALFISCMCHDLDHRGTNNSFQVASKSVLAALYSSEGSVMERHHFAQAIAILNTHGCNIFDHFSRKDYQRMLDLMRDIILATDLAHHLRIFKDLQKMAEVGYDRNNRQHHRLLLCLLMTSCDLSDQTKGWKTTRKIAELIYKEFFSQGDLEKAMGNRPMEMMDREKAYIPELQISFMEHIAMPIYKLLQDLFPK-AAELYERVASNREHWTKVS 920

[Close]

BLAST of Phosphodiesterase vs. Ensembl Mouse
Match: Pde2a (phosphodiesterase 2A, cGMP-stimulated [Source:MGI Symbol;Acc:MGI:2446107])

HSP 1 Score: 781.556 bits (2017), Expect = 0.000e+0
Identity = 392/860 (45.58%), Postives = 569/860 (66.16%), Query Frame = 1

Query:  295 RELLLGLSNIVSYEEIPDAVKTTINRVFPNSNSVRLEWINTR-----ENSTKSIRSNGWMNENKIIPQSSLIINR---KDRLQEQYSDYFDSENSDNFGIIVPLISSEMKEFQAFLSFSCQEFNQNEKKLLQTFENQVKVMFQRLERLKNSKDSNLQQSNL---QDTKLDSSDFYIDSTILSLCADLHDRDPGILQVKIIRFLKQRIHMESAFILTISNNNLELVCQAQDEQIFDPEKRFRVTDSIFERIMKEKICAQLSDVNMFQDKLNELELLTNIKWNSFLCVPIINQSDGCVSALVCMINKIGSNQSFTAEDISITQHLFQYTAAVLTSSVAFQMERRLKIQTETMLQVAMNIFRKLGDLTGLLKEIMTEAKKLTNAERCSVFLVDNDTKELVSKVFDGLPTISEQSQHPVEIRIPVTQGVAGRVATTGEMLNIVDAYSHPLFYRGVDEETGYKTRNILCFPIKDENEKVVGVAQLCNKINGPCFTNYDEDIAKAFSVYCCISIMHSLMYKKVQDAQHRNKLANELMIYHMQVNEDTVKWLTSCGYPDLMDIKEDFNSFECIPRDIKEHDSALAVLGMFNTLGFISKWRLSRPTLSRFILMIKRGYRDPPYHNWTHAFSVAHFIYLCITNLPLHGQLLPIELLALFVASLCHDIDHRGTNNSFQVTSKSVLAALYSSEGSVLERHHFSQTICVLNSEGCNIFENFSRQDYHHVLDLIRDIILATDLAHHLRIISDQRKMIDTFYDSNSNHHHVLLMDLLMTSADLSDQSKNWKNTRAVAQLIYEEFFSQGDMEKSIGQKPAEQMDRERACVPSLQMSFLDGIALPCFQLFADLYPLFGQKMIENITNNRKKWEKLN 2841
            ++ LL L  ++    +  A +  ++ V P   +V    ++       E+    +   G + E  +I Q  L  N     D L +  +        D   +++PL+  E     A +   C + + +E++ LQ  E    V  +R++ L+  +   +Q +++   +D K +      D  IL LC +L D D   LQ+K++++L+Q        +L +S +NL+L C+   +++   E  F +T     +++++K C QL D+    D + +L+ +   +  + LCVP+I+++   V AL C  NK+G +  FT ED  + QH F YT  VLTS++AFQ E++LK + + +LQVA N+F  L D++ LL+EI+TEA+ L+NAE CSVFL+D +  ELV+KVFDG   + ++S    EIRIP  QG+AG VATTG++LNI DAY+HPLFYRGVD+ TG++TRNILCFPIK+EN++V+GVA+L NKINGP F+ +DED+A AFS+YC ISI HSL+YKKV +AQ+R+ LANE+M+YHM+V++D    L   G   +  I  +F +F   PR + E D+++A+L M   + FI+ +++  PTL+RF LM+K+GYRDPPYHNW HAFSV+HF YL   NL L   L  IE+ ALF++ +CHD+DHRGTNNSFQV SKSVLAALYSSEGSV+ERHHF+Q I +LN+ GCNIF++FSR+DY  +LDL+RDIILATDLAHHLRI  D +KM +  YD N+  HH LL+ LLMTS DLSDQ+K WK TR +A+LIY+EFFSQGD+EK++G +P E MDRE+A +P LQ+SF++ IA+P ++L  DL+P    ++ E + +NR+ W K++
Sbjct:   46 QDALLSLGAVIDIAGLRQAARDALSAVLPKVETVYTYLLDGESRLVCEDPPHELPQEGKIRE-AVISQKRLSCNGLGPSDLLGKPLARLVAPLAPDMQVLVIPLLDKETGSVAAVILVHCGQLSDSEEQSLQVVEKHALVALRRVQALQQRRPEAVQNTSVDASEDQKDEKGYTDHDRKILQLCGELFDLDATSLQLKVLQYLQQETQATHCCLLLVSEDNLQLSCKVIGDKVLGEEVSFPLTMGRLGQVVEDKQCIQLKDLT--SDDVQQLQNMLGCELQAMLCVPVISRATDQVVALACAFNKLGGD-FFTDEDEHVIQHCFHYTGTVLTSTLAFQKEQKLKCECQALLQVAKNLFTHLDDVSVLLQEIITEARNLSNAEICSVFLLDQN--ELVAKVFDG-GVVDDES---YEIRIPADQGIAGHVATTGQILNIPDAYAHPLFYRGVDDSTGFRTRNILCFPIKNENQEVIGVAELVNKINGPWFSKFDEDLATAFSIYCGISIAHSLLYKKVNEAQYRSHLANEMMMYHMKVSDDEYTKLLHDGIQPVAAIDSNFANFTYTPRSLPEDDTSMAILSMLQDMNFINNYKIDCPTLARFCLMVKKGYRDPPYHNWMHAFSVSHFCYLLYKNLELSNYLEDIEIFALFISCMCHDLDHRGTNNSFQVASKSVLAALYSSEGSVMERHHFAQAIAILNTHGCNIFDHFSRKDYQRMLDLMRDIILATDLAHHLRIFKDLQKMAEVGYDRNNRQHHRLLLCLLMTSCDLSDQTKGWKTTRKIAELIYKEFFSQGDLEKAMGNRPMEMMDREKAYIPELQISFMEHIAMPIYKLLQDLFPK-AAELYERVASNREHWTKVS 894

[Close]

Query:  295 RELLLGLSNIVSYEEIPDAVKTTINRVFPNSNSVRLEWINTR-----ENSTKSIRSNGWMNENKIIPQSSLIINR---KDRLQEQYSDYFDSENSDNFGIIVPLISSEMKEFQAFLSFSCQEFNQNEKKLLQTFENQVKVMFQRLERLKNSKDSNLQQSNL---QDTKLDSSDFYIDSTILSLCADLHDRDPGILQVKIIRFLKQRIHMESAFILTISNNNLELVCQAQDEQIFDPEKRFRVTDSIFERIMKEKICAQLSDVNMFQDKLNELELLTNIKWNSFLCVPIINQSDGCVSALVCMINKIGSNQSFTAEDISITQHLFQYTAAVLTSSVAFQMERRLKIQTETMLQVAMNIFRKLGDLTGLLKEIMTEAKKLTNAERCSVFLVDNDTKELVSKVFDGLPTISEQSQHPVEIRIPVTQGVAGRVATTGEMLNIVDAYSHPLFYRGVDEETGYKTRNILCFPIKDENEKVVGVAQLCNKINGPCFTNYDEDIAKAFSVYCCISIMHSLMYKKVQDAQHRNKLANELMIYHMQVNEDTVKWLTSCGYPDLMDIKEDFNSFECIPRDIKEHDSALAVLGMFNTLGFISKWRLSRPTLSRFILMIKRGYRDPPYHNWTHAFSVAHFIYLCITNLPLHGQLLPIELLALFVASLCHDIDHRGTNNSFQVTSKSVLAALYSSEGSVLERHHFSQTICVLNSEGCNIFENFSRQDYHHVLDLIRDIILATDLAHHLRIISDQRKMIDTFYDSNSNHHHVLLMDLLMTSADLSDQSKNWKNTRAVAQLIYEEFFSQGDMEKSIGQKPAEQMDRERACVPSLQMSFLDGIALPCFQLFADLYPLFGQKMIENITNNRKKWEKLN 2841
            ++ LL L  ++    +  A +  ++ V P   +V    ++       E+    +   G + E  +I Q  L  N     D L +  +        D   +++PL+  E     A +   C + + +E++ LQ  E    V  +R++ L+  +   +Q +++   +D K +      D  IL LC +L D D   LQ+K++++L+Q        +L +S +NL+L C+   +++   E  F +T     +++++K C QL D+    D + +L+ +   +  + LCVP+I+++   V AL C  NK+G +  FT ED  + QH F YT  VLTS++AFQ E++LK + + +LQVA N+F  L D++ LL+EI+TEA+ L+NAE CSVFL+D +  ELV+KVFDG   + ++S    EIRIP  QG+AG VATTG++LNI DAY+HPLFYRGVD+ TG++TRNILCFPIK+EN++V+GVA+L NKINGP F+ +DED+A AFS+YC ISI HSL+YKKV +AQ+R+ LANE+M+YHM+V++D    L   G   +  I  +F +F   PR + E D+++A+L M   + FI+ +++  PTL+RF LM+K+GYRDPPYHNW HAFSV+HF YL   NL L   L  IE+ ALF++ +CHD+DHRGTNNSFQV SKSVLAALYSSEGSV+ERHHF+Q I +LN+ GCNIF++FSR+DY  +LDL+RDIILATDLAHHLRI  D +KM +  YD N+  HH LL+ LLMTS DLSDQ+K WK TR +A+LIY+EFFSQGD+EK++G +P E MDRE+A +P LQ+SF++ IA+P ++L  DL+P    ++ E + +NR+ W K++
Sbjct:   46 QDALLSLGAVIDIAGLRQAARDALSAVLPKVETVYTYLLDGESRLVCEDPPHELPQEGKIRE-AVISQKRLSCNGLGPSDLLGKPLARLVAPLAPDMQVLVIPLLDKETGSVAAVILVHCGQLSDSEEQSLQVVEKHALVALRRVQALQQRRPEAVQNTSVDASEDQKDEKGYTDHDRKILQLCGELFDLDATSLQLKVLQYLQQETQATHCCLLLVSEDNLQLSCKVIGDKVLGEEVSFPLTMGRLGQVVEDKQCIQLKDLT--SDDVQQLQNMLGCELQAMLCVPVISRATDQVVALACAFNKLGGD-FFTDEDEHVIQHCFHYTGTVLTSTLAFQKEQKLKCECQALLQVAKNLFTHLDDVSVLLQEIITEARNLSNAEICSVFLLDQN--ELVAKVFDG-GVVDDES---YEIRIPADQGIAGHVATTGQILNIPDAYAHPLFYRGVDDSTGFRTRNILCFPIKNENQEVIGVAELVNKINGPWFSKFDEDLATAFSIYCGISIAHSLLYKKVNEAQYRSHLANEMMMYHMKVSDDEYTKLLHDGIQPVAAIDSNFANFTYTPRSLPEDDTSMAILSMLQDMNFINNYKIDCPTLARFCLMVKKGYRDPPYHNWMHAFSVSHFCYLLYKNLELSNYLEDIEIFALFISCMCHDLDHRGTNNSFQVASKSVLAALYSSEGSVMERHHFAQAIAILNTHGCNIFDHFSRKDYQRMLDLMRDIILATDLAHHLRIFKDLQKMAEVGYDRNNRQHHRLLLCLLMTSCDLSDQTKGWKTTRKIAELIYKEFFSQGDLEKAMGNRPMEMMDREKAYIPELQISFMEHIAMPIYKLLQDLFPK-AAELYERVASNREHWTKVS 894

[Close]

BLAST of Phosphodiesterase vs. Ensembl Mouse
Match: Pde2a (phosphodiesterase 2A, cGMP-stimulated [Source:MGI Symbol;Acc:MGI:2446107])

HSP 1 Score: 780.785 bits (2015), Expect = 0.000e+0
Identity = 392/860 (45.58%), Postives = 569/860 (66.16%), Query Frame = 1

Query:  295 RELLLGLSNIVSYEEIPDAVKTTINRVFPNSNSVRLEWINTR-----ENSTKSIRSNGWMNENKIIPQSSLIINR---KDRLQEQYSDYFDSENSDNFGIIVPLISSEMKEFQAFLSFSCQEFNQNEKKLLQTFENQVKVMFQRLERLKNSKDSNLQQSNL---QDTKLDSSDFYIDSTILSLCADLHDRDPGILQVKIIRFLKQRIHMESAFILTISNNNLELVCQAQDEQIFDPEKRFRVTDSIFERIMKEKICAQLSDVNMFQDKLNELELLTNIKWNSFLCVPIINQSDGCVSALVCMINKIGSNQSFTAEDISITQHLFQYTAAVLTSSVAFQMERRLKIQTETMLQVAMNIFRKLGDLTGLLKEIMTEAKKLTNAERCSVFLVDNDTKELVSKVFDGLPTISEQSQHPVEIRIPVTQGVAGRVATTGEMLNIVDAYSHPLFYRGVDEETGYKTRNILCFPIKDENEKVVGVAQLCNKINGPCFTNYDEDIAKAFSVYCCISIMHSLMYKKVQDAQHRNKLANELMIYHMQVNEDTVKWLTSCGYPDLMDIKEDFNSFECIPRDIKEHDSALAVLGMFNTLGFISKWRLSRPTLSRFILMIKRGYRDPPYHNWTHAFSVAHFIYLCITNLPLHGQLLPIELLALFVASLCHDIDHRGTNNSFQVTSKSVLAALYSSEGSVLERHHFSQTICVLNSEGCNIFENFSRQDYHHVLDLIRDIILATDLAHHLRIISDQRKMIDTFYDSNSNHHHVLLMDLLMTSADLSDQSKNWKNTRAVAQLIYEEFFSQGDMEKSIGQKPAEQMDRERACVPSLQMSFLDGIALPCFQLFADLYPLFGQKMIENITNNRKKWEKLN 2841
            ++ LL L  ++    +  A +  ++ V P   +V    ++       E+    +   G + E  +I Q  L  N     D L +  +        D   +++PL+  E     A +   C + + +E++ LQ  E    V  +R++ L+  +   +Q +++   +D K +      D  IL LC +L D D   LQ+K++++L+Q        +L +S +NL+L C+   +++   E  F +T     +++++K C QL D+    D + +L+ +   +  + LCVP+I+++   V AL C  NK+G +  FT ED  + QH F YT  VLTS++AFQ E++LK + + +LQVA N+F  L D++ LL+EI+TEA+ L+NAE CSVFL+D +  ELV+KVFDG   + ++S    EIRIP  QG+AG VATTG++LNI DAY+HPLFYRGVD+ TG++TRNILCFPIK+EN++V+GVA+L NKINGP F+ +DED+A AFS+YC ISI HSL+YKKV +AQ+R+ LANE+M+YHM+V++D    L   G   +  I  +F +F   PR + E D+++A+L M   + FI+ +++  PTL+RF LM+K+GYRDPPYHNW HAFSV+HF YL   NL L   L  IE+ ALF++ +CHD+DHRGTNNSFQV SKSVLAALYSSEGSV+ERHHF+Q I +LN+ GCNIF++FSR+DY  +LDL+RDIILATDLAHHLRI  D +KM +  YD N+  HH LL+ LLMTS DLSDQ+K WK TR +A+LIY+EFFSQGD+EK++G +P E MDRE+A +P LQ+SF++ IA+P ++L  DL+P    ++ E + +NR+ W K++
Sbjct:   56 QDALLSLGAVIDIAGLRQAARDALSAVLPKVETVYTYLLDGESRLVCEDPPHELPQEGKIRE-AVISQKRLSCNGLGPSDLLGKPLARLVAPLAPDMQVLVIPLLDKETGSVAAVILVHCGQLSDSEEQSLQVVEKHALVALRRVQALQQRRPEAVQNTSVDASEDQKDEKGYTDHDRKILQLCGELFDLDATSLQLKVLQYLQQETQATHCCLLLVSEDNLQLSCKVIGDKVLGEEVSFPLTMGRLGQVVEDKQCIQLKDLT--SDDVQQLQNMLGCELQAMLCVPVISRATDQVVALACAFNKLGGD-FFTDEDEHVIQHCFHYTGTVLTSTLAFQKEQKLKCECQALLQVAKNLFTHLDDVSVLLQEIITEARNLSNAEICSVFLLDQN--ELVAKVFDG-GVVDDES---YEIRIPADQGIAGHVATTGQILNIPDAYAHPLFYRGVDDSTGFRTRNILCFPIKNENQEVIGVAELVNKINGPWFSKFDEDLATAFSIYCGISIAHSLLYKKVNEAQYRSHLANEMMMYHMKVSDDEYTKLLHDGIQPVAAIDSNFANFTYTPRSLPEDDTSMAILSMLQDMNFINNYKIDCPTLARFCLMVKKGYRDPPYHNWMHAFSVSHFCYLLYKNLELSNYLEDIEIFALFISCMCHDLDHRGTNNSFQVASKSVLAALYSSEGSVMERHHFAQAIAILNTHGCNIFDHFSRKDYQRMLDLMRDIILATDLAHHLRIFKDLQKMAEVGYDRNNRQHHRLLLCLLMTSCDLSDQTKGWKTTRKIAELIYKEFFSQGDLEKAMGNRPMEMMDREKAYIPELQISFMEHIAMPIYKLLQDLFPK-AAELYERVASNREHWTKVS 904

[Close]

BLAST of Phosphodiesterase vs. UniProt/SwissProt
Match: sp|Q01062|PDE2A_RAT (cGMP-dependent 3',5'-cyclic phosphodiesterase OS=Rattus norvegicus OX=10116 GN=Pde2a PE=1 SV=2)

HSP 1 Score: 785.793 bits (2028), Expect = 0.000e+0
Identity = 395/862 (45.82%), Postives = 566/862 (65.66%), Query Frame = 1

Query:  295 RELLLGLSNIVSYEEIPDAVKTTINRVFPNSNSVRLEWINTRENSTKSIRSNGWMNENKIIPQSSLIINRK----------DRLQEQYSDYFDSENSDNFGIIVPLISSEMKEFQAFLSFSCQEFNQNEKKLLQTFENQVKVMFQRLERLKNSKDSNLQQSNL---QDTKLDSSDFYIDSTILSLCADLHDRDPGILQVKIIRFLKQRIHMESAFILTISNNNLELVCQAQDEQIFDPEKRFRVTDSIFERIMKEKICAQLSDVNMFQDKLNELELLTNIKWNSFLCVPIINQSDGCVSALVCMINKIGSNQSFTAEDISITQHLFQYTAAVLTSSVAFQMERRLKIQTETMLQVAMNIFRKLGDLTGLLKEIMTEAKKLTNAERCSVFLVDNDTKELVSKVFDGLPTISEQSQHPVEIRIPVTQGVAGRVATTGEMLNIVDAYSHPLFYRGVDEETGYKTRNILCFPIKDENEKVVGVAQLCNKINGPCFTNYDEDIAKAFSVYCCISIMHSLMYKKVQDAQHRNKLANELMIYHMQVNEDTVKWLTSCGYPDLMDIKEDFNSFECIPRDIKEHDSALAVLGMFNTLGFISKWRLSRPTLSRFILMIKRGYRDPPYHNWTHAFSVAHFIYLCITNLPLHGQLLPIELLALFVASLCHDIDHRGTNNSFQVTSKSVLAALYSSEGSVLERHHFSQTICVLNSEGCNIFENFSRQDYHHVLDLIRDIILATDLAHHLRIISDQRKMIDTFYDSNSNHHHVLLMDLLMTSADLSDQSKNWKNTRAVAQLIYEEFFSQGDMEKSIGQKPAEQMDRERACVPSLQMSFLDGIALPCFQLFADLYPLFGQKMIENITNNRKKWEKLN 2841
            ++ LL L  ++    +  A K  ++ V P   +V    ++           +    E KI      +I+RK          D L +  +        D   +++PL+  E     A +   C + + +E++ LQ  E    V  QR++ L+  +   +Q ++    +D K +      D  IL LC +L+D D   LQ+K++R+L+Q        +L +S +NL+L C+   E++   E  F +T     +++++K C QL D+    D + +L+ +   +  + LCVP+I+++   V AL C  NK+G +  FT ED    QH F YT  VLTS++AFQ E++LK + + +LQVA N+F  L D++ LL+EI+TEA+ L+NAE CSVFL+D +  ELV+KVFDG   + ++S    EIRIP  QG+AG VATTG++LNI DAY+HPLFYRGVD+ TG++TRNILCFPIK+EN++V+GVA+L NKINGP F+ +DED+A AFS+YC ISI HSL+YKKV +AQ+R+ LANE+M+YHM+V++D    L   G   +  I  +F +F   PR + E D+++A+L M   + FI+ +++  PTL+RF LM+K+GYRDPPYHNW HAFSV+HF YL   NL L   L  IE+ ALF++ +CHD+DHRGTNNSFQV SKSVLAALYSSEGSV+ERHHF+Q I +LN+ GCNIF++FSR+DY  +LDL+RDIILATDLAHHLRI  D +KM +  YD N+  HH LL+ LLMTS DLSDQ+K WK TR +A+LIY+EFFSQGD+EK++G +P E MDRE+A +P LQ+SF++ IA+P ++L  DL+P    ++ E + +NR+ W K++
Sbjct:   39 QDALLSLGAVIDIAGLRQAAKDALSAVLPKVETVYTYLVDGESRLVCEDPPHELPQEGKI---REAVISRKRLSCDGLGPSDLLGKPLARLVAPLAPDTQVLVIPLLDKETGTVAAVILVHCGQLSDSEEQSLQVVEKHALVALQRVQALQQRRPEAVQNTSADPSEDQKDEKGYTAHDRKILQLCGELYDLDATSLQLKVLRYLQQETQATHCCLLLVSEDNLQLSCKVIGEKVLGEEVSFPLTMGRLGQVVEDKQCIQLKDLT--SDDVQQLQNMLGCELRAMLCVPVISRATDQVVALACAFNKLGGD-FFTDEDERAIQHCFHYTGTVLTSTLAFQKEQKLKCECQALLQVAKNLFTHLDDVSVLLQEIITEARNLSNAEICSVFLLDQN--ELVAKVFDG-GVVDDES---YEIRIPADQGIAGHVATTGQILNIPDAYAHPLFYRGVDDSTGFRTRNILCFPIKNENQEVIGVAELVNKINGPWFSKFDEDLATAFSIYCGISIAHSLLYKKVNEAQYRSHLANEMMMYHMKVSDDEYTKLLHDGIQPVAAIDSNFANFTYTPRSLPEDDTSMAILSMLQDMNFINNYKIDCPTLARFCLMVKKGYRDPPYHNWMHAFSVSHFCYLLYKNLELSNYLEDIEIFALFISCMCHDLDHRGTNNSFQVASKSVLAALYSSEGSVMERHHFAQAIAILNTHGCNIFDHFSRKDYQRMLDLMRDIILATDLAHHLRIFKDLQKMAEVGYDRNNKQHHRLLLCLLMTSCDLSDQTKGWKTTRKIAELIYKEFFSQGDLEKAMGNRPMEMMDREKAYIPELQISFMEHIAMPIYKLLQDLFPK-AAELYERVASNREHWTKVS 887

[Close]

BLAST of Phosphodiesterase vs. UniProt/SwissProt
Match: sp|Q922S4|PDE2A_MOUSE (cGMP-dependent 3',5'-cyclic phosphodiesterase OS=Mus musculus OX=10090 GN=Pde2a PE=1 SV=4)

HSP 1 Score: 783.097 bits (2021), Expect = 0.000e+0
Identity = 393/863 (45.54%), Postives = 570/863 (66.05%), Query Frame = 1

Query:  295 RELLLGLSNIVSYEEIPDAVKTTINRVFPNSNSVRLEWINTR-----ENSTKSIRSNGWMNENKIIPQSSLIINR---KDRLQEQYSDYFDSENSDNFGIIVPLISSEMKEFQAFLSFSCQEFNQNEKKLLQTFENQVKVMFQRLERLKNSKDSNLQQSNL---QDTKLDSSDFYIDSTILSLCADLHDRDPGILQVKIIRFLKQRIHMESAFILTISNNNLELVCQAQDEQIFDPEKRFRVTDSIFERIMKEKICAQLSDVNMFQDKLNELELLTNIKWNSFLCVPIINQSDGCVSALVCMINKIGSN---QSFTAEDISITQHLFQYTAAVLTSSVAFQMERRLKIQTETMLQVAMNIFRKLGDLTGLLKEIMTEAKKLTNAERCSVFLVDNDTKELVSKVFDGLPTISEQSQHPVEIRIPVTQGVAGRVATTGEMLNIVDAYSHPLFYRGVDEETGYKTRNILCFPIKDENEKVVGVAQLCNKINGPCFTNYDEDIAKAFSVYCCISIMHSLMYKKVQDAQHRNKLANELMIYHMQVNEDTVKWLTSCGYPDLMDIKEDFNSFECIPRDIKEHDSALAVLGMFNTLGFISKWRLSRPTLSRFILMIKRGYRDPPYHNWTHAFSVAHFIYLCITNLPLHGQLLPIELLALFVASLCHDIDHRGTNNSFQVTSKSVLAALYSSEGSVLERHHFSQTICVLNSEGCNIFENFSRQDYHHVLDLIRDIILATDLAHHLRIISDQRKMIDTFYDSNSNHHHVLLMDLLMTSADLSDQSKNWKNTRAVAQLIYEEFFSQGDMEKSIGQKPAEQMDRERACVPSLQMSFLDGIALPCFQLFADLYPLFGQKMIENITNNRKKWEKLN 2841
            ++ LL L  ++    +  A +  ++ V P   +V    ++       E+    +   G + E  +I Q  L  N     D L +  +        D   +++PL+  E     A +   C + + +E++ LQ  E    V  +R++ L+  +   +Q +++   +D K +      D  IL LC +L D D   LQ+K++++L+Q        +L +S +NL+L C+   +++   E  F +T     +++++K C QL D+    D + +L+ +   +  + LCVP+I+++   V AL C  NK+G +    SFT ED  + QH F YT  VLTS++AFQ E++LK + + +LQVA N+F  L D++ LL+EI+TEA+ L+NAE CSVFL+D +  ELV+KVFDG   + ++S    EIRIP  QG+AG VATTG++LNI DAY+HPLFYRGVD+ TG++TRNILCFPIK+EN++V+GVA+L NKINGP F+ +DED+A AFS+YC ISI HSL+YKKV +AQ+R+ LANE+M+YHM+V++D    L   G   +  I  +F +F   PR + E D+++A+L M   + FI+ +++  PTL+RF LM+K+GYRDPPYHNW HAFSV+HF YL   NL L   L  IE+ ALF++ +CHD+DHRGTNNSFQV SKSVLAALYSSEGSV+ERHHF+Q I +LN+ GCNIF++FSR+DY  +LDL+RDIILATDLAHHLRI  D +KM +  YD N+  HH LL+ LLMTS DLSDQ+K WK TR +A+LIY+EFFSQGD+EK++G +P E MDRE+A +P LQ+SF++ IA+P ++L  DL+P    ++ E + +NR+ W K++
Sbjct:   46 QDALLSLGAVIDIAGLRQAARDALSAVLPKVETVYTYLLDGESRLVCEDPPHELPQEGKIRE-AVISQKRLSCNGLGPSDLLGKPLARLVAPLAPDMQVLVIPLLDKETGSVAAVILVHCGQLSDSEEQSLQVVEKHALVALRRVQALQQRRPEAVQNTSVDASEDQKDEKGYTDHDRKILQLCGELFDLDATSLQLKVLQYLQQETQATHCCLLLVSEDNLQLSCKVIGDKVLGEEVSFPLTMGRLGQVVEDKQCIQLKDLT--SDDVQQLQNMLGCELQAMLCVPVISRATDQVVALACAFNKLGGDFPTSSFTDEDEHVIQHCFHYTGTVLTSTLAFQKEQKLKCECQALLQVAKNLFTHLDDVSVLLQEIITEARNLSNAEICSVFLLDQN--ELVAKVFDG-GVVDDES---YEIRIPADQGIAGHVATTGQILNIPDAYAHPLFYRGVDDSTGFRTRNILCFPIKNENQEVIGVAELVNKINGPWFSKFDEDLATAFSIYCGISIAHSLLYKKVNEAQYRSHLANEMMMYHMKVSDDEYTKLLHDGIQPVAAIDSNFANFTYTPRSLPEDDTSMAILSMLQDMNFINNYKIDCPTLARFCLMVKKGYRDPPYHNWMHAFSVSHFCYLLYKNLELSNYLEDIEIFALFISCMCHDLDHRGTNNSFQVASKSVLAALYSSEGSVMERHHFAQAIAILNTHGCNIFDHFSRKDYQRMLDLMRDIILATDLAHHLRIFKDLQKMAEVGYDRNNRQHHRLLLCLLMTSCDLSDQTKGWKTTRKIAELIYKEFFSQGDLEKAMGNRPMEMMDREKAYIPELQISFMEHIAMPIYKLLQDLFPK-AAELYERVASNREHWTKVS 898

[Close]

BLAST of Phosphodiesterase vs. UniProt/SwissProt
Match: sp|P14099|PDE2A_BOVIN (cGMP-dependent 3',5'-cyclic phosphodiesterase OS=Bos taurus OX=9913 GN=PDE2A PE=1 SV=2)

HSP 1 Score: 774.237 bits (1998), Expect = 0.000e+0
Identity = 390/864 (45.14%), Postives = 566/864 (65.51%), Query Frame = 1

Query:  295 RELLLGLSNIVSYEEIPDAVKTTINRVFPNSNSVRLEWINTR-----ENSTKSIRSNGWMNENKIIPQSSLIINR---KDRLQEQYSDYFDSENSDNFGIIVPLISSEMKEFQAFLSFSCQEFNQNEKKLLQTFENQVKVMFQRLERLKNSKDS-------NLQQSNLQDTKLDSSDFYIDSTILSLCADLHDRDPGILQVKIIRFLKQRIHMESAFILTISNNNLELVCQAQDEQIFDPEKRFRVTDSIFERIMKEKICAQLSDVNMFQDKLNELELLTNIKWNSFLCVPIINQSDGCVSALVCMINKIGSNQSFTAEDISITQHLFQYTAAVLTSSVAFQMERRLKIQTETMLQVAMNIFRKLGDLTGLLKEIMTEAKKLTNAERCSVFLVDNDTKELVSKVFDGLPTISEQSQHPVEIRIPVTQGVAGRVATTGEMLNIVDAYSHPLFYRGVDEETGYKTRNILCFPIKDENEKVVGVAQLCNKINGPCFTNYDEDIAKAFSVYCCISIMHSLMYKKVQDAQHRNKLANELMIYHMQVNEDTVKWLTSCGYPDLMDIKEDFNSFECIPRDIKEHDSALAVLGMFNTLGFISKWRLSRPTLSRFILMIKRGYRDPPYHNWTHAFSVAHFIYLCITNLPLHGQLLPIELLALFVASLCHDIDHRGTNNSFQVTSKSVLAALYSSEGSVLERHHFSQTICVLNSEGCNIFENFSRQDYHHVLDLIRDIILATDLAHHLRIISDQRKMIDTFYDSNSNHHHVLLMDLLMTSADLSDQSKNWKNTRAVAQLIYEEFFSQGDMEKSIGQKPAEQMDRERACVPSLQMSFLDGIALPCFQLFADLYPLFGQKMIENITNNRKKWEKLN 2841
            ++ LL L +++    +  AVK  ++ V P   +V    ++       E     +   G + E  +I +  L  N     D   +  +        D   +++PL+  E     A +   C + + NE+  LQ  E    V  +R++ L+  + S       N  +    D K   +    D  IL LC +L+D D   LQ+K++++L+Q        +L +S +NL+L C+   +++ + E  F +T     +++++K   QL D+    + + +L+ +   +  + LCVP+I+++   V AL C  NK+G +  FT +D  + QH F YT+ VLTS++AFQ E++LK + + +LQVA N+F  L D++ LL+EI+TEA+ L+NAE CSVFL+D +  ELV+KVFDG   + ++S    EIRIP  QG+AG VATTG++LNI DAY+HPLFYRGVD+ TG++TRNILCFPIK+EN++V+GVA+L NKINGP F+ +DED+A AFS+YC ISI HSL+YKKV +AQ+R+ LANE+M+YHM+V++D    L   G   +  I  +F SF   PR + E D+++A+L M   + FI+ +++  PTL+RF LM+K+GYRDPPYHNW HAFSV+HF YL   NL L   L  +E+ ALF++ +CHD+DHRGTNNSFQV SKSVLAALYSSEGSV+ERHHF+Q I +LN+ GCNIF++FSR+DY  +LDL+RDIILATDLAHHLRI  D +KM +  YD  +  HH LL+ LLMTS DLSDQ+K WK TR +A+LIY+EFFSQGD+EK++G +P E MDRE+A +P LQ+SF++ IA+P ++L  DL+P    ++ E + +NR+ W K++
Sbjct:   27 QDALLSLGSVIDVAGLQQAVKEALSAVLPKVETVYTYLLDGESRLVCEEPPHELPQEGKVRE-AVISRKRLGCNGLGPSDLPGKPLARLVAPLAPDTQVLVIPLVDKEAGAVAAVILVHCGQLSDNEEWSLQAVEKHTLVALKRVQALQQRESSVAPEATQNPPEEAAGDQKGGVAYTNQDRKILQLCGELYDLDASSLQLKVLQYLQQETQASRCCLLLVSEDNLQLSCKVIGDKVLEEEISFPLTTGRLGQVVEDKKSIQLKDLT--SEDMQQLQSMLGCEVQAMLCVPVISRATDQVVALACAFNKLGGDL-FTDQDEHVIQHCFHYTSTVLTSTLAFQKEQKLKCECQALLQVAKNLFTHLDDVSVLLQEIITEARNLSNAEICSVFLLDQN--ELVAKVFDG-GVVEDES---YEIRIPADQGIAGHVATTGQILNIPDAYAHPLFYRGVDDSTGFRTRNILCFPIKNENQEVIGVAELVNKINGPWFSKFDEDLATAFSIYCGISIAHSLLYKKVNEAQYRSHLANEMMMYHMKVSDDEYTKLLHDGIQPVAAIDSNFASFTYTPRSLPEDDTSMAILSMLQDMNFINNYKIDCPTLARFCLMVKKGYRDPPYHNWMHAFSVSHFCYLLYKNLELTNYLEDMEIFALFISCMCHDLDHRGTNNSFQVASKSVLAALYSSEGSVMERHHFAQAIAILNTHGCNIFDHFSRKDYQRMLDLMRDIILATDLAHHLRIFKDLQKMAEVGYDRTNKQHHSLLLCLLMTSCDLSDQTKGWKTTRKIAELIYKEFFSQGDLEKAMGNRPMEMMDREKAYIPELQISFMEHIAMPIYKLLQDLFPK-AAELYERVASNREHWTKVS 879

[Close]

BLAST of Phosphodiesterase vs. UniProt/SwissProt
Match: sp|O00408|PDE2A_HUMAN (cGMP-dependent 3',5'-cyclic phosphodiesterase OS=Homo sapiens OX=9606 GN=PDE2A PE=1 SV=1)

HSP 1 Score: 770.385 bits (1988), Expect = 0.000e+0
Identity = 395/864 (45.72%), Postives = 567/864 (65.62%), Query Frame = 1

Query:  295 RELLLGLSNIVSYEEIPDAVKTTINRVFPNSNSVRLEWINTR-----ENSTKSIRSNGWMNENKIIPQSSLIINR---KDRLQEQYSDYFDSENSDNFGIIVPLISSEMKEFQAFLSFSCQEFNQNEKKLLQTFEN-------QVKVMFQRLERLKNSKDSNLQQSNLQDTKLDSSDFYIDSTILSLCADLHDRDPGILQVKIIRFLKQRIHMESAFILTISNNNLELVCQAQDEQIFDPEKRFRVTDSIFERIMKEKICAQLSDVNMFQDKLNELELLTNIKWNSFLCVPIINQSDGCVSALVCMINKIGSNQSFTAEDISITQHLFQYTAAVLTSSVAFQMERRLKIQTETMLQVAMNIFRKLGDLTGLLKEIMTEAKKLTNAERCSVFLVDNDTKELVSKVFDGLPTISEQSQHPVEIRIPVTQGVAGRVATTGEMLNIVDAYSHPLFYRGVDEETGYKTRNILCFPIKDENEKVVGVAQLCNKINGPCFTNYDEDIAKAFSVYCCISIMHSLMYKKVQDAQHRNKLANELMIYHMQVNEDTVKWLTSCGYPDLMDIKEDFNSFECIPRDIKEHDSALAVLGMFNTLGFISKWRLSRPTLSRFILMIKRGYRDPPYHNWTHAFSVAHFIYLCITNLPLHGQLLPIELLALFVASLCHDIDHRGTNNSFQVTSKSVLAALYSSEGSVLERHHFSQTICVLNSEGCNIFENFSRQDYHHVLDLIRDIILATDLAHHLRIISDQRKMIDTFYDSNSNHHHVLLMDLLMTSADLSDQSKNWKNTRAVAQLIYEEFFSQGDMEKSIGQKPAEQMDRERACVPSLQMSFLDGIALPCFQLFADLYPLFGQKMIENITNNRKKWEKLN 2841
            ++ LL L +++    +  AVK  ++ V P   +V    ++       E+    +   G + E  II Q  L  N     D   +  +        D   +++PL   E     A +   C + + NE+  LQ  E        +V+V+ QR  R       N  +   +D K  ++    D  IL LC +L+D D   LQ+K++++L+Q        +L +S +NL+L C+   +++   E  F +T  + + ++++K   QL D+    + + +L+ +   +  + LCVP+I+++   V AL C  NK+  +  FT ED  + QH F YT+ VLTS++AFQ E++LK + + +LQVA N+F  L D++ LL+EI+TEA+ L+NAE CSVFL+D +  ELV+KVFDG   + ++S    EIRIP  QG+AG VATTG++LNI DAY+HPLFYRGVD+ TG++TRNILCFPIK+EN++V+GVA+L NKINGP F+ +DED+A AFS+YC ISI HSL+YKKV +AQ+R+ LANE+M+YHM+V++D    L   G   +  I  +F SF   PR + E D+++A+L M   + FI+ +++  PTL+RF LM+K+GYRDPPYHNW HAFSV+HF YL   NL L   L  IE+ ALF++ +CHD+DHRGTNNSFQV SKSVLAALYSSEGSV+ERHHF+Q I +LN+ GCNIF++FSR+DY  +LDL+RDIILATDLAHHLRI  D +KM +  YD N+  HH LL+ LLMTS DLSDQ+K WK TR +A+LIY+EFFSQGD+EK++G +P E MDRE+A +P LQ+SF++ IA+P ++L  DL+P    ++ E + +NR+ W K++
Sbjct:   48 QDALLSLGSVIDISGLQRAVKEALSAVLPRVETVYTYLLDGESQLVCEDPPHELPQEGKVRE-AIISQKRLGCNGLGFSDLPGKPLARLVAPLAPDTQVLVMPLADKEAGAVAAVILVHCGQLSDNEEWSLQAVEKHTLVALRRVQVLQQRGPREAPRAVQNPPEGTAEDQKGGAAYTDRDRKILQLCGELYDLDASSLQLKVLQYLQQETRASRCCLLLVSEDNLQLSCKVIGDKVLGEEVSFPLTGCLGQ-VVEDKKSIQLKDLT--SEDVQQLQSMLGCELQAMLCVPVISRATDQVVALACAFNKLEGDL-FTDEDEHVIQHCFHYTSTVLTSTLAFQKEQKLKCECQALLQVAKNLFTHLDDVSVLLQEIITEARNLSNAEICSVFLLDQN--ELVAKVFDG-GVVDDES---YEIRIPADQGIAGHVATTGQILNIPDAYAHPLFYRGVDDSTGFRTRNILCFPIKNENQEVIGVAELVNKINGPWFSKFDEDLATAFSIYCGISIAHSLLYKKVNEAQYRSHLANEMMMYHMKVSDDEYTKLLHDGIQPVAAIDSNFASFTYTPRSLPEDDTSMAILSMLQDMNFINNYKIDCPTLARFCLMVKKGYRDPPYHNWMHAFSVSHFCYLLYKNLELTNYLEDIEIFALFISCMCHDLDHRGTNNSFQVASKSVLAALYSSEGSVMERHHFAQAIAILNTHGCNIFDHFSRKDYQRMLDLMRDIILATDLAHHLRIFKDLQKMAEVGYDRNNKQHHRLLLCLLMTSCDLSDQTKGWKTTRKIAELIYKEFFSQGDLEKAMGNRPMEMMDREKAYIPELQISFMEHIAMPIYKLLQDLFPK-AAELYERVASNREHWTKVS 899

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BLAST of Phosphodiesterase vs. UniProt/SwissProt
Match: sp|P30645|PDE2_CAEEL (Probable 3',5'-cyclic phosphodiesterase pde-2 OS=Caenorhabditis elegans OX=6239 GN=pde-2 PE=3 SV=4)

HSP 1 Score: 358.221 bits (918), Expect = 8.486e-108
Identity = 204/530 (38.49%), Postives = 304/530 (57.36%), Query Frame = 1

Query: 1318 VAMNIFRKL----GDLTGLLKEIMTEAKKLTNAERCSVFLVDNDTKELVSKVFDGLPTISEQSQHPVEIRIPVTQGVAGRVATTGEMLNIVDAYSHPLFYRGVDEETGYKTRNILCFPIKDENEKVVGVAQLCNKINGPCFTNYDEDIAKAFSVYCCISIMHSLMYKKVQDAQHRNKLANELMIYHMQ--VNEDTVKWLTSCGYPDLMDIKEDFNSFECIPRDIKEHDSALAVLGMFNTLGFISKWRLSRPTLSRFILMIKRGYRDPPYHNWTHAFSVAHFIYLCITNLPLHGQLLPIELLALFVASLCHDIDHRGTNNSFQVTS--KSVLAALYSSEGSVLERHHFSQTICVLNSEGCNIFENFSRQDYHHVLDLIRDIILATDLAHHLRIISDQRKMIDTFYDSNSNHHHVLLMDLLMTSADLSDQSKNWKNTRAVAQLIYEEFFSQGDMEKSIGQKPAEQMDRERACVPSLQMSFLDGIALPCFQLFADLYPLFGQKMIENITNNRKKWEKLNEDIKNGKISANIFQ 2883
            V M+IF +      +L+ L+  I+ EAKK T AE  +VFL D D K++V          + ++      +  +  G+ G+VA+T   +NI D    P F   +DE+   K RN++ FP+ D +  ++GV  L NK NG  F+ +DE   K FS +   SI H+++ K++++ + R  +  E  I      + E  +  L +    D     ++F  F   PR + E+    A +  F  LGF   ++L++  LS  +L +  GYR  PYHNW+HAF+V HF +L +    +   L  +E L+L +A LCHDIDHRGT NSFQ+ S  K+ L+ LYS+EGSVLERHHF+QTI +L  E C+I EN    D+  +++ IR++ILATD++ HLR     + MI   Y+  S  H  LLM L+MT++DLSDQ+KN+ N + +A+ IY EFF+QGD+E  +G KP E MDR  A VP++Q+ FL  I +P FQL A + P  G+   E I  N   W  L+E+++N   + N  +
Sbjct:  163 VPMSIFDQFLCLTNNLSALISCIIAEAKKNTEAEDYAVFLHDEDNKQMV--------LFNNETMLMTGKKFDMGYGIVGKVASTMRTMNIRDVSRCPFFNEEIDEQFSIKARNLIAFPLIDSSCSLIGVIVLYNKENG--FSRHDEKYIKRFSYFVANSIAHAILAKQIEEVRTRIHMVEEFKIQGEDAVIEEVDIMRLVNDPLRDWRYFSQNFADFSFPPRSVGENHFHRASMMFFEDLGFSMLYKLNKRKLSYLVLRVSAGYRPVPYHNWSHAFAVTHFCWLTLRTDAIRRALSDMERLSLLIACLCHDIDHRGTTNSFQMQSLQKTPLSVLYSTEGSVLERHHFAQTIKLLQQEECSILENLPAADFRTIVNTIREVILATDISAHLRKQERIKTMISEGYNPMSFDHRYLLMCLVMTASDLSDQAKNFHNAKRIAENIYLEFFAQGDLELQLGVKPLEMMDRTNAYVPTVQIDFLFKIGVPVFQLLASVVPE-GRTTSEAIDANHLCWVALDEEVRNNPSATNTLE 681

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BLAST of Phosphodiesterase vs. TrEMBL
Match: A0A4Z2CV85 (Phosphodiesterase OS=Schistosoma japonicum OX=6182 GN=EWB00_007250 PE=3 SV=1)

HSP 1 Score: 789.645 bits (2038), Expect = 0.000e+0
Identity = 421/845 (49.82%), Postives = 568/845 (67.22%), Query Frame = 1

Query:  484 SSLIINRKDRLQEQYSDYFDSENSDNFGIIVPLISSEMK-EFQAFLSFSCQEFNQNEKKLLQTFENQVKVMFQRLERLK-----NSKDSNLQQSNLQDTKLDSSDFYID----STILSLCADLHDRDPGILQVKIIRFLKQRIHMESAFILTISNNNLELVCQAQDEQIFDPEKRFRVTDSIFERIMK------------EKICAQLSDVNMFQDKLNELELLTNI----KWNSFLCVPIINQSDGCVSALVCMINKIGSNQSFTAEDISITQHLFQYTAAVLTSSVAFQMERRLKIQTETMLQVAMNIFRKLGDLTGLLKEIMTEAKKLTNAERCSVFLVDNDTKELVSKVFDGLPTISEQSQH-----------PVEIRIPVTQGVAGRVATTGEMLNIVDAYSHPLFYRGVDEETGYKTRNILCFPIKDENEKVVGVAQLCNKINGPCFTNYDEDIAKAFSVYCCISIMHSLMYKKVQDAQHRNKLANELMIYHMQVNEDTVKWLTSCGYPDLMDIKEDFNSFECIPRDIK-EHDSALAVLGMFNTLGFISKWRLSRPTLSRFILMIKRGYRDPPYHNWTHAFSVAHFIYLCITNLPL-HGQLLPIELLALFVASLCHDIDHRGTNNSFQVTSKSVLAALYSSEGSVLERHHFSQTICVLNSEGCNIFENFSRQDYHHVLDLIRDIILATDLAHHLRIISDQRKMIDTFYDSNSNHHHVLLMDLLMTSADLSDQSKNWKNTRAVAQLIYEEFFSQGDMEKSIGQKPAEQMDRERACVPSLQMSFLDGIALPCFQLFADLYPLFGQKMIENITNNRKKWEKLNEDIKNGKISANIFQLFHRDI 2901
            +S I++     + Q    F+++N++ + I   L + + + ++ A      +   +      Q F++Q+     R+ RL+     +S  S+L+Q     ++   +  +I+      IL LC  L D     LQ K++R+L QR + E+ FI+  + +  ELVC    ++IFD E  +   DS+F  IM+            E+    LS +++    +N    +TN+    + NSFLC P+  +S      +VC+INK  S   FT  D  I +  F+YTA +L SS++ Q ER ++ +TE ML+VA NIF  + DLT LL +IM EA+ LT AERCSVFL+D++T  LV+KV DGLPT   ++ H           P EIR+ + QG+AG VATTGE+LNI DAY+HPLFYRGVD+ETG++TRNILCFPIK+E + +VGVAQLCNKIN P FT  DED+AK FS+YCCISI+HSLMYK VQDAQHR KLANELM+YHM+V+ED   WL++C   D+     + +SFE +PR+I+ E+++ L  L MF+ L  I++WR+SR TL++FILM++RGYR+P YHNW HAF+VAHFIY+CI NLPL + QL  IE+LALFVASLCHDIDHRGTNNSFQV SKSVLAALYSSEGSVLERHHFSQTICVLN++GCNIFEN S++DY  +LD IRDIILATDL+HHLRI+S   +M    YD   +  H LL+ LLMTSADLSDQ+K W NT  VA+LIYEEFF QGDMEKS+G  P + MDRERACVP+LQ+SFLD I LP +++  +LYP     +++ I  NR  W+ + E ++ G+I  N  ++F+ ++
Sbjct:   86 TSFIVHLASVSKNQNMSNFNTKNTNQYMISFELNNEDKRSDYVAHFVMILESLPKAHLHKAQLFKSQLSCTLNRIIRLEQFNELSSTLSSLKQRYPCCSQGIEASTWINRKDNELILKLCESLWDTQTNRLQHKVLRYLMQRTNSENGFIVMRNTDTSELVCYCIGDEIFD-ESTYIENDSLFNEIMQSGKTFTSTTPNSEQKQVLLSVLSIHNAYMNNEHPITNLHEEMEINSFLCSPVFTRSSEYPIGVVCLINKKDS--QFTQSDEFIIEECFRYTAPILLSSLSCQNERYIRDRTEDMLKVARNIFTHMMDLTNLLLKIMQEAQNLTKAERCSVFLLDSETNVLVAKVLDGLPTAPNKNTHFTTTDGKIVTLPEEIRLSLNQGIAGHVATTGELLNIKDAYAHPLFYRGVDKETGFRTRNILCFPIKNEKDGIVGVAQLCNKINHPFFTRADEDVAKTFSIYCCISIVHSLMYKNVQDAQHRTKLANELMMYHMKVDEDKKNWLSTCEIKDINSFLPNTSSFESLPRNIQPENETYLCTLSMFHNLNLINRWRISRRTLAQFILMVRRGYRNPAYHNWMHAFTVAHFIYVCIKNLPLANKQLEDIEILALFVASLCHDIDHRGTNNSFQVQSKSVLAALYSSEGSVLERHHFSQTICVLNTDGCNIFENVSKEDYSQLLDHIRDIILATDLSHHLRIMSKLEEMSHRGYDVTKSEDHYLLLCLLMTSADLSDQTKPWNNTVYVAKLIYEEFFQQGDMEKSLGHNPIDSMDRERACVPNLQISFLDYIILPLYRVLNNLYPQCS-SILDTIEKNRDNWKTILELVEKGEIKGNGSEIFNHNL 926

[Close]

BLAST of Phosphodiesterase vs. TrEMBL
Match: A0A0G2K876 (Phosphodiesterase OS=Rattus norvegicus OX=10116 GN=Pde2a PE=1 SV=1)

HSP 1 Score: 786.563 bits (2030), Expect = 0.000e+0
Identity = 395/859 (45.98%), Postives = 564/859 (65.66%), Query Frame = 1

Query:  304 LLGLSNIVSYEEIPDAVKTTINRVFPNSNSVRLEWINTRENSTKSIRSNGWMNENKIIPQSSLIINRK----------DRLQEQYSDYFDSENSDNFGIIVPLISSEMKEFQAFLSFSCQEFNQNEKKLLQTFENQVKVMFQRLERLKNSKDSNLQQSNL---QDTKLDSSDFYIDSTILSLCADLHDRDPGILQVKIIRFLKQRIHMESAFILTISNNNLELVCQAQDEQIFDPEKRFRVTDSIFERIMKEKICAQLSDVNMFQDKLNELELLTNIKWNSFLCVPIINQSDGCVSALVCMINKIGSNQSFTAEDISITQHLFQYTAAVLTSSVAFQMERRLKIQTETMLQVAMNIFRKLGDLTGLLKEIMTEAKKLTNAERCSVFLVDNDTKELVSKVFDGLPTISEQSQHPVEIRIPVTQGVAGRVATTGEMLNIVDAYSHPLFYRGVDEETGYKTRNILCFPIKDENEKVVGVAQLCNKINGPCFTNYDEDIAKAFSVYCCISIMHSLMYKKVQDAQHRNKLANELMIYHMQVNEDTVKWLTSCGYPDLMDIKEDFNSFECIPRDIKEHDSALAVLGMFNTLGFISKWRLSRPTLSRFILMIKRGYRDPPYHNWTHAFSVAHFIYLCITNLPLHGQLLPIELLALFVASLCHDIDHRGTNNSFQVTSKSVLAALYSSEGSVLERHHFSQTICVLNSEGCNIFENFSRQDYHHVLDLIRDIILATDLAHHLRIISDQRKMIDTFYDSNSNHHHVLLMDLLMTSADLSDQSKNWKNTRAVAQLIYEEFFSQGDMEKSIGQKPAEQMDRERACVPSLQMSFLDGIALPCFQLFADLYPLFGQKMIENITNNRKKWEKLN 2841
            LL L  ++    +  A K  ++ V P   +V    ++           +    E KI      +I+RK          D L +  +        D   +++PL+  E     A +   C + + +E++ LQ  E    V  QR++ L+  +   +Q ++    +D K +      D  IL LC +L+D D   LQ+K++R+L+Q        +L +S +NL+L C+   E++   E  F +T     +++++K C QL D+    D + +L+ +   +  + LCVP+I+++   V AL C  NK+G +  FT ED    QH F YT  VLTS++AFQ E++LK + + +LQVA N+F  L D++ LL+EI+TEA+ L+NAE CSVFL+D +  ELV+KVFDG   + ++S    EIRIP  QG+AG VATTG++LNI DAY+HPLFYRGVD+ TG++TRNILCFPIK+EN++V+GVA+L NKINGP F+ +DED+A AFS+YC ISI HSL+YKKV +AQ+R+ LANE+M+YHM+V++D    L   G   +  I  +F +F   PR + E D+++A+L M   + FI+ +++  PTL+RF LM+K+GYRDPPYHNW HAFSV+HF YL   NL L   L  IE+ ALF++ +CHD+DHRGTNNSFQV SKSVLAALYSSEGSV+ERHHF+Q I +LN+ GCNIF++FSR+DY  +LDL+RDIILATDLAHHLRI  D +KM +  YD N+  HH LL+ LLMTS DLSDQ+K WK TR +A+LIY+EFFSQGD+EK++G +P E MDRE+A +P LQ+SF++ IA+P ++L  DL+P    ++ E + +NR+ W K++
Sbjct:   30 LLSLGAVIDIAGLRQAAKDALSAVLPKVETVYTYLVDGESRLVCEDPPHELPQEGKI---REAVISRKRLSCDGLGPSDLLGKPLARLVAPLAPDTQVLVIPLLDKETGTVAAVILVHCGQLSDSEEQSLQVVEKHALVALQRVQALQQRRPEAVQNTSADPSEDQKDEKGYTAHDRKILQLCGELYDLDATSLQLKVLRYLQQETQATHCCLLLVSEDNLQLSCKVIGEKVLGEEVSFPLTMGRLGQVVEDKQCIQLKDLT--SDDVQQLQNMLGCELRAMLCVPVISRATDQVVALACAFNKLGGD-FFTDEDERAIQHCFHYTGTVLTSTLAFQKEQKLKCECQALLQVAKNLFTHLDDVSVLLQEIITEARNLSNAEICSVFLLDQN--ELVAKVFDG-GVVDDES---YEIRIPADQGIAGHVATTGQILNIPDAYAHPLFYRGVDDSTGFRTRNILCFPIKNENQEVIGVAELVNKINGPWFSKFDEDLATAFSIYCGISIAHSLLYKKVNEAQYRSHLANEMMMYHMKVSDDEYTKLLHDGIQPVAAIDSNFANFTYTPRSLPEDDTSMAILSMLQDMNFINNYKIDCPTLARFCLMVKKGYRDPPYHNWMHAFSVSHFCYLLYKNLELSNYLEDIEIFALFISCMCHDLDHRGTNNSFQVASKSVLAALYSSEGSVMERHHFAQAIAILNTHGCNIFDHFSRKDYQRMLDLMRDIILATDLAHHLRIFKDLQKMAEVGYDRNNKQHHRLLLCLLMTSCDLSDQTKGWKTTRKIAELIYKEFFSQGDLEKAMGNRPMEMMDREKAYIPELQISFMEHIAMPIYKLLQDLFPK-AAELYERVASNREHWTKVS 875

[Close]

BLAST of Phosphodiesterase vs. TrEMBL
Match: F8WFW5 (Phosphodiesterase OS=Rattus norvegicus OX=10116 GN=Pde2a PE=1 SV=1)

HSP 1 Score: 786.178 bits (2029), Expect = 0.000e+0
Identity = 395/862 (45.82%), Postives = 566/862 (65.66%), Query Frame = 1

Query:  295 RELLLGLSNIVSYEEIPDAVKTTINRVFPNSNSVRLEWINTRENSTKSIRSNGWMNENKIIPQSSLIINRK----------DRLQEQYSDYFDSENSDNFGIIVPLISSEMKEFQAFLSFSCQEFNQNEKKLLQTFENQVKVMFQRLERLKNSKDSNLQQSNL---QDTKLDSSDFYIDSTILSLCADLHDRDPGILQVKIIRFLKQRIHMESAFILTISNNNLELVCQAQDEQIFDPEKRFRVTDSIFERIMKEKICAQLSDVNMFQDKLNELELLTNIKWNSFLCVPIINQSDGCVSALVCMINKIGSNQSFTAEDISITQHLFQYTAAVLTSSVAFQMERRLKIQTETMLQVAMNIFRKLGDLTGLLKEIMTEAKKLTNAERCSVFLVDNDTKELVSKVFDGLPTISEQSQHPVEIRIPVTQGVAGRVATTGEMLNIVDAYSHPLFYRGVDEETGYKTRNILCFPIKDENEKVVGVAQLCNKINGPCFTNYDEDIAKAFSVYCCISIMHSLMYKKVQDAQHRNKLANELMIYHMQVNEDTVKWLTSCGYPDLMDIKEDFNSFECIPRDIKEHDSALAVLGMFNTLGFISKWRLSRPTLSRFILMIKRGYRDPPYHNWTHAFSVAHFIYLCITNLPLHGQLLPIELLALFVASLCHDIDHRGTNNSFQVTSKSVLAALYSSEGSVLERHHFSQTICVLNSEGCNIFENFSRQDYHHVLDLIRDIILATDLAHHLRIISDQRKMIDTFYDSNSNHHHVLLMDLLMTSADLSDQSKNWKNTRAVAQLIYEEFFSQGDMEKSIGQKPAEQMDRERACVPSLQMSFLDGIALPCFQLFADLYPLFGQKMIENITNNRKKWEKLN 2841
            ++ LL L  ++    +  A K  ++ V P   +V    ++           +    E KI      +I+RK          D L +  +        D   +++PL+  E     A +   C + + +E++ LQ  E    V  QR++ L+  +   +Q ++    +D K +      D  IL LC +L+D D   LQ+K++R+L+Q        +L +S +NL+L C+   E++   E  F +T     +++++K C QL D+    D + +L+ +   +  + LCVP+I+++   V AL C  NK+G +  FT ED    QH F YT  VLTS++AFQ E++LK + + +LQVA N+F  L D++ LL+EI+TEA+ L+NAE CSVFL+D +  ELV+KVFDG   + ++S    EIRIP  QG+AG VATTG++LNI DAY+HPLFYRGVD+ TG++TRNILCFPIK+EN++V+GVA+L NKINGP F+ +DED+A AFS+YC ISI HSL+YKKV +AQ+R+ LANE+M+YHM+V++D    L   G   +  I  +F +F   PR + E D+++A+L M   + FI+ +++  PTL+RF LM+K+GYRDPPYHNW HAFSV+HF YL   NL L   L  IE+ ALF++ +CHD+DHRGTNNSFQV SKSVLAALYSSEGSV+ERHHF+Q I +LN+ GCNIF++FSR+DY  +LDL+RDIILATDLAHHLRI  D +KM +  YD N+  HH LL+ LLMTS DLSDQ+K WK TR +A+LIY+EFFSQGD+EK++G +P E MDRE+A +P LQ+SF++ IA+P ++L  DL+P    ++ E + +NR+ W K++
Sbjct:   46 QDALLSLGAVIDIAGLRQAAKDALSAVLPKVETVYTYLVDGESRLVCEDPPHELPQEGKI---REAVISRKRLSCDGLGPSDLLGKPLARLVAPLAPDTQVLVIPLLDKETGTVAAVILVHCGQLSDSEEQSLQVVEKHALVALQRVQALQQRRPEAVQNTSADPSEDQKDEKGYTAHDRKILQLCGELYDLDATSLQLKVLRYLQQETQATHCCLLLVSEDNLQLSCKVIGEKVLGEEVSFPLTMGRLGQVVEDKQCIQLKDLT--SDDVQQLQNMLGCELRAMLCVPVISRATDQVVALACAFNKLGGD-FFTDEDERAIQHCFHYTGTVLTSTLAFQKEQKLKCECQALLQVAKNLFTHLDDVSVLLQEIITEARNLSNAEICSVFLLDQN--ELVAKVFDG-GVVDDES---YEIRIPADQGIAGHVATTGQILNIPDAYAHPLFYRGVDDSTGFRTRNILCFPIKNENQEVIGVAELVNKINGPWFSKFDEDLATAFSIYCGISIAHSLLYKKVNEAQYRSHLANEMMMYHMKVSDDEYTKLLHDGIQPVAAIDSNFANFTYTPRSLPEDDTSMAILSMLQDMNFINNYKIDCPTLARFCLMVKKGYRDPPYHNWMHAFSVSHFCYLLYKNLELSNYLEDIEIFALFISCMCHDLDHRGTNNSFQVASKSVLAALYSSEGSVMERHHFAQAIAILNTHGCNIFDHFSRKDYQRMLDLMRDIILATDLAHHLRIFKDLQKMAEVGYDRNNKQHHRLLLCLLMTSCDLSDQTKGWKTTRKIAELIYKEFFSQGDLEKAMGNRPMEMMDREKAYIPELQISFMEHIAMPIYKLLQDLFPK-AAELYERVASNREHWTKVS 894

[Close]

BLAST of Phosphodiesterase vs. TrEMBL
Match: F7D3W5 (Phosphodiesterase OS=Mus musculus OX=10090 GN=Gm45837 PE=1 SV=1)

HSP 1 Score: 781.941 bits (2018), Expect = 0.000e+0
Identity = 392/857 (45.74%), Postives = 567/857 (66.16%), Query Frame = 1

Query:  304 LLGLSNIVSYEEIPDAVKTTINRVFPNSNSVRLEWINTR-----ENSTKSIRSNGWMNENKIIPQSSLIINR---KDRLQEQYSDYFDSENSDNFGIIVPLISSEMKEFQAFLSFSCQEFNQNEKKLLQTFENQVKVMFQRLERLKNSKDSNLQQSNL---QDTKLDSSDFYIDSTILSLCADLHDRDPGILQVKIIRFLKQRIHMESAFILTISNNNLELVCQAQDEQIFDPEKRFRVTDSIFERIMKEKICAQLSDVNMFQDKLNELELLTNIKWNSFLCVPIINQSDGCVSALVCMINKIGSNQSFTAEDISITQHLFQYTAAVLTSSVAFQMERRLKIQTETMLQVAMNIFRKLGDLTGLLKEIMTEAKKLTNAERCSVFLVDNDTKELVSKVFDGLPTISEQSQHPVEIRIPVTQGVAGRVATTGEMLNIVDAYSHPLFYRGVDEETGYKTRNILCFPIKDENEKVVGVAQLCNKINGPCFTNYDEDIAKAFSVYCCISIMHSLMYKKVQDAQHRNKLANELMIYHMQVNEDTVKWLTSCGYPDLMDIKEDFNSFECIPRDIKEHDSALAVLGMFNTLGFISKWRLSRPTLSRFILMIKRGYRDPPYHNWTHAFSVAHFIYLCITNLPLHGQLLPIELLALFVASLCHDIDHRGTNNSFQVTSKSVLAALYSSEGSVLERHHFSQTICVLNSEGCNIFENFSRQDYHHVLDLIRDIILATDLAHHLRIISDQRKMIDTFYDSNSNHHHVLLMDLLMTSADLSDQSKNWKNTRAVAQLIYEEFFSQGDMEKSIGQKPAEQMDRERACVPSLQMSFLDGIALPCFQLFADLYPLFGQKMIENITNNRKKWEKLN 2841
            LL L  ++    +  A +  ++ V P   +V    ++       E+    +   G + E  +I Q  L  N     D L +  +        D   +++PL+  E     A +   C + + +E++ LQ  E    V  +R++ L+  +   +Q +++   +D K +      D  IL LC +L D D   LQ+K++++L+Q        +L +S +NL+L C+   +++   E  F +T     +++++K C QL D+    D + +L+ +   +  + LCVP+I+++   V AL C  NK+G +  FT ED  + QH F YT  VLTS++AFQ E++LK + + +LQVA N+F  L D++ LL+EI+TEA+ L+NAE CSVFL+D +  ELV+KVFDG   + ++S    EIRIP  QG+AG VATTG++LNI DAY+HPLFYRGVD+ TG++TRNILCFPIK+EN++V+GVA+L NKINGP F+ +DED+A AFS+YC ISI HSL+YKKV +AQ+R+ LANE+M+YHM+V++D    L   G   +  I  +F +F   PR + E D+++A+L M   + FI+ +++  PTL+RF LM+K+GYRDPPYHNW HAFSV+HF YL   NL L   L  IE+ ALF++ +CHD+DHRGTNNSFQV SKSVLAALYSSEGSV+ERHHF+Q I +LN+ GCNIF++FSR+DY  +LDL+RDIILATDLAHHLRI  D +KM +  YD N+  HH LL+ LLMTS DLSDQ+K WK TR +A+LIY+EFFSQGD+EK++G +P E MDRE+A +P LQ+SF++ IA+P ++L  DL+P    ++ E + +NR+ W K++
Sbjct:   75 LLSLGAVIDIAGLRQAARDALSAVLPKVETVYTYLLDGESRLVCEDPPHELPQEGKIRE-AVISQKRLSCNGLGPSDLLGKPLARLVAPLAPDMQVLVIPLLDKETGSVAAVILVHCGQLSDSEEQSLQVVEKHALVALRRVQALQQRRPEAVQNTSVDASEDQKDEKGYTDHDRKILQLCGELFDLDATSLQLKVLQYLQQETQATHCCLLLVSEDNLQLSCKVIGDKVLGEEVSFPLTMGRLGQVVEDKQCIQLKDLT--SDDVQQLQNMLGCELQAMLCVPVISRATDQVVALACAFNKLGGD-FFTDEDEHVIQHCFHYTGTVLTSTLAFQKEQKLKCECQALLQVAKNLFTHLDDVSVLLQEIITEARNLSNAEICSVFLLDQN--ELVAKVFDG-GVVDDES---YEIRIPADQGIAGHVATTGQILNIPDAYAHPLFYRGVDDSTGFRTRNILCFPIKNENQEVIGVAELVNKINGPWFSKFDEDLATAFSIYCGISIAHSLLYKKVNEAQYRSHLANEMMMYHMKVSDDEYTKLLHDGIQPVAAIDSNFANFTYTPRSLPEDDTSMAILSMLQDMNFINNYKIDCPTLARFCLMVKKGYRDPPYHNWMHAFSVSHFCYLLYKNLELSNYLEDIEIFALFISCMCHDLDHRGTNNSFQVASKSVLAALYSSEGSVMERHHFAQAIAILNTHGCNIFDHFSRKDYQRMLDLMRDIILATDLAHHLRIFKDLQKMAEVGYDRNNRQHHRLLLCLLMTSCDLSDQTKGWKTTRKIAELIYKEFFSQGDLEKAMGNRPMEMMDREKAYIPELQISFMEHIAMPIYKLLQDLFPK-AAELYERVASNREHWTKVS 920

[Close]

BLAST of Phosphodiesterase vs. TrEMBL
Match: Q5PR72 (Phosphodiesterase OS=Mus musculus OX=10090 GN=Pde2a PE=1 SV=1)

HSP 1 Score: 781.556 bits (2017), Expect = 0.000e+0
Identity = 392/860 (45.58%), Postives = 569/860 (66.16%), Query Frame = 1

Query:  295 RELLLGLSNIVSYEEIPDAVKTTINRVFPNSNSVRLEWINTR-----ENSTKSIRSNGWMNENKIIPQSSLIINR---KDRLQEQYSDYFDSENSDNFGIIVPLISSEMKEFQAFLSFSCQEFNQNEKKLLQTFENQVKVMFQRLERLKNSKDSNLQQSNL---QDTKLDSSDFYIDSTILSLCADLHDRDPGILQVKIIRFLKQRIHMESAFILTISNNNLELVCQAQDEQIFDPEKRFRVTDSIFERIMKEKICAQLSDVNMFQDKLNELELLTNIKWNSFLCVPIINQSDGCVSALVCMINKIGSNQSFTAEDISITQHLFQYTAAVLTSSVAFQMERRLKIQTETMLQVAMNIFRKLGDLTGLLKEIMTEAKKLTNAERCSVFLVDNDTKELVSKVFDGLPTISEQSQHPVEIRIPVTQGVAGRVATTGEMLNIVDAYSHPLFYRGVDEETGYKTRNILCFPIKDENEKVVGVAQLCNKINGPCFTNYDEDIAKAFSVYCCISIMHSLMYKKVQDAQHRNKLANELMIYHMQVNEDTVKWLTSCGYPDLMDIKEDFNSFECIPRDIKEHDSALAVLGMFNTLGFISKWRLSRPTLSRFILMIKRGYRDPPYHNWTHAFSVAHFIYLCITNLPLHGQLLPIELLALFVASLCHDIDHRGTNNSFQVTSKSVLAALYSSEGSVLERHHFSQTICVLNSEGCNIFENFSRQDYHHVLDLIRDIILATDLAHHLRIISDQRKMIDTFYDSNSNHHHVLLMDLLMTSADLSDQSKNWKNTRAVAQLIYEEFFSQGDMEKSIGQKPAEQMDRERACVPSLQMSFLDGIALPCFQLFADLYPLFGQKMIENITNNRKKWEKLN 2841
            ++ LL L  ++    +  A +  ++ V P   +V    ++       E+    +   G + E  +I Q  L  N     D L +  +        D   +++PL+  E     A +   C + + +E++ LQ  E    V  +R++ L+  +   +Q +++   +D K +      D  IL LC +L D D   LQ+K++++L+Q        +L +S +NL+L C+   +++   E  F +T     +++++K C QL D+    D + +L+ +   +  + LCVP+I+++   V AL C  NK+G +  FT ED  + QH F YT  VLTS++AFQ E++LK + + +LQVA N+F  L D++ LL+EI+TEA+ L+NAE CSVFL+D +  ELV+KVFDG   + ++S    EIRIP  QG+AG VATTG++LNI DAY+HPLFYRGVD+ TG++TRNILCFPIK+EN++V+GVA+L NKINGP F+ +DED+A AFS+YC ISI HSL+YKKV +AQ+R+ LANE+M+YHM+V++D    L   G   +  I  +F +F   PR + E D+++A+L M   + FI+ +++  PTL+RF LM+K+GYRDPPYHNW HAFSV+HF YL   NL L   L  IE+ ALF++ +CHD+DHRGTNNSFQV SKSVLAALYSSEGSV+ERHHF+Q I +LN+ GCNIF++FSR+DY  +LDL+RDIILATDLAHHLRI  D +KM +  YD N+  HH LL+ LLMTS DLSDQ+K WK TR +A+LIY+EFFSQGD+EK++G +P E MDRE+A +P LQ+SF++ IA+P ++L  DL+P    ++ E + +NR+ W K++
Sbjct:   46 QDALLSLGAVIDIAGLRQAARDALSAVLPKVETVYTYLLDGESRLVCEDPPHELPQEGKIRE-AVISQKRLSCNGLGPSDLLGKPLARLVAPLAPDMQVLVIPLLDKETGSVAAVILVHCGQLSDSEEQSLQVVEKHALVALRRVQALQQRRPEAVQNTSVDASEDQKDEKGYTDHDRKILQLCGELFDLDATSLQLKVLQYLQQETQATHCCLLLVSEDNLQLSCKVIGDKVLGEEVSFPLTMGRLGQVVEDKQCIQLKDLT--SDDVQQLQNMLGCELQAMLCVPVISRATDQVVALACAFNKLGGD-FFTDEDEHVIQHCFHYTGTVLTSTLAFQKEQKLKCECQALLQVAKNLFTHLDDVSVLLQEIITEARNLSNAEICSVFLLDQN--ELVAKVFDG-GVVDDES---YEIRIPADQGIAGHVATTGQILNIPDAYAHPLFYRGVDDSTGFRTRNILCFPIKNENQEVIGVAELVNKINGPWFSKFDEDLATAFSIYCGISIAHSLLYKKVNEAQYRSHLANEMMMYHMKVSDDEYTKLLHDGIQPVAAIDSNFANFTYTPRSLPEDDTSMAILSMLQDMNFINNYKIDCPTLARFCLMVKKGYRDPPYHNWMHAFSVSHFCYLLYKNLELSNYLEDIEIFALFISCMCHDLDHRGTNNSFQVASKSVLAALYSSEGSVMERHHFAQAIAILNTHGCNIFDHFSRKDYQRMLDLMRDIILATDLAHHLRIFKDLQKMAEVGYDRNNRQHHRLLLCLLMTSCDLSDQTKGWKTTRKIAELIYKEFFSQGDLEKAMGNRPMEMMDREKAYIPELQISFMEHIAMPIYKLLQDLFPK-AAELYERVASNREHWTKVS 894

[Close]

BLAST of Phosphodiesterase vs. Ensembl Cavefish
Match: pde11a (phosphodiesterase 11a [Source:ZFIN;Acc:ZDB-GENE-070912-207])

HSP 1 Score: 343.969 bits (881), Expect = 6.836e-103
Identity = 200/607 (32.95%), Postives = 340/607 (56.01%), Query Frame = 1

Query: 1069 NELELLTNIKWNSFLCVPIINQSDGCVSALVCMINKIGSNQSFTAEDISITQHLFQYTAAVLTSSVAFQMERRLKIQTETMLQVAMNIFRKLGDLTGLLKEIMTEAKKLTNAERCSVFLVDNDTKELV--SKVFDGL-PTISEQSQHPVEIRIP--------VTQGVAGRVATTGEMLNIVDAYSHPLFYRGVDEETGYKTRNILCFPIKDENEKVVGVAQLCNKINGPCFTNYDEDIAKAFSVYCCISIMHSLMYKKVQDAQHRNKLANELMIYHMQVNEDTVKWLTSCGYPDLMDIKEDFNSFECIPRDIKEHDSAL-AVLGMFNTLGFISKWRLSRPTLSRFILMIKRGYRDPPYHNWTHAFSVAHFIYLCITNLPLHGQLLPIELLALFVASLCHDIDHRGTNNSFQVTSKSVLAALYSSEGSVLERHHFSQTICVLNSEGCNIFENFSRQDYHHVLDLIRDIILATDLAHHLRIISDQRKMIDTF-YDSNSNHHHVLLMDLLMTSADLSDQSKNWKNTRAVAQLIYEEFFSQGDMEKS-IGQKPAEQMDRERAC-VPSLQMSFLDGIALPCFQLFADLYPLFGQKMIENITNNRKKWEKLNE 2844
            +E++ LT  K  S LC+PI N SDG +  +   INK      FT +D  + Q    +    ++++  F   R+   ++  +L+V  ++F +  DL  ++++IM  A+ L   ERCSV L+++    +V  +K F+ L P  S  +++  +  +         +   +A  VA+TG  +NI DAY  P F    D+ +G+  R++LC PI + N +++GVAQ+ N+++G  F + D+ + +AF ++C + I +++MY +V+ +  +  +A +++ YH   ++  V    +   P + ++  D  SF+    D+   D+ + A L MF  LG + K+++   TL R++L +++ YR   YHNW HAF+V   ++  +T       L  +E+LAL V  +CHD+DHRGTNN+FQ  + S L+ LY +  + LE HHF+  + +L SEG NIF N S +DY  ++ L++  ILATDL  +    +   +++    Y+ N   H  +   +LMT+ DL   +K W  +R VA+L+  EFF QGD E+S +   P+   DR R   +PSLQ+ ++DGI  P ++  A L P   Q M++ I  NR KW++L++
Sbjct:  288 DEIDKLTGYKTKSLLCMPIRN-SDGEIIGVAQAINKSPGGALFTEDDEKVLQMYLPFCGIAISNAQLFAASRKEYDRSRALLEVVNDLFEEQTDLEKIVRKIMHRAQTLLKCERCSVQLLEDIESPVVKFTKSFELLSPKCSADTENSFKDSMEKSSYSDWLINNSIAELVASTGLPVNISDAYQDPRFDAEADQFSGFHIRSVLCVPIWNSNHQIIGVAQVLNRLDGKPFDDADQRLFEAFVIFCGLGINNTIMYDQVKKSWAKQSVALDVLSYHATCSKTEVDKFKAANIPLVCELGIDKLSFDDFSLDV---DAMITAALRMFMELGMLQKFKIDYETLCRWLLTVRKNYRMVLYHNWRHAFNVCQCMFSLLTTAGFQETLSELEILALIVGCVCHDLDHRGTNNAFQAKTGSALSLLYGTSAT-LEHHHFNHAVMILQSEGHNIFSNLSSRDYGDLMQLLKQSILATDLTLYFENRNSFFELVKKGEYNWNVKEHRDMFRSMLMTACDLGAVTKPWDISRKVAELVTSEFFEQGDRERSELKLTPSAIFDRNRKDELPSLQLEWIDGICSPLYETLAKLNPKL-QPMVDVIQANRAKWDELHQ 888

HSP 2 Score: 107.842 bits (268), Expect = 2.394e-23
Identity = 68/209 (32.54%), Postives = 118/209 (56.46%), Query Frame = 1

Query: 1255 TSSVAFQMERRLKIQTETMLQVAMNIFRKLGDLTGLLKEIMTEAKKLTNAERCSVFLVDN--DTKELVSKVFDG------LPTISEQSQHPVEIRIPVTQGVAGRVATTGEMLNIVDAYSHPLFYRGVDEETGYKTRNILCFPIKDENEKVVGVAQLCNK-INGPCFTNYDEDIAKAFSVYCCISIMHSLMYKKVQDAQHRNKLANELM 1854
            +++V F+   +   + E  L++  +I   L DLT L  +I+     + +A+RCS+FLV+   + K LVSK FD       LP++S       E+++P  +G+ G VA  GE +NI DAY    F   +D+ TGYKT+++LC PI++ + +++GVAQ  NK   G  FT  DE + + +  +C I+I ++ ++   +    R++   E++
Sbjct:  168 STAVDFKYYLKEHNEREFFLELVKDISNDL-DLTSLSYKILVFVCIMVDADRCSLFLVEGTANKKTLVSKFFDVHAGTTVLPSLSNSD----EVQVPWGKGIIGYVAEHGETVNIPDAYQDHRFSDEIDKLTGYKTKSLLCMPIRNSDGEIIGVAQAINKSPGGALFTEDDEKVLQMYLPFCGIAISNAQLFAASRKEYDRSRALLEVV 371

[Close]

BLAST of Phosphodiesterase vs. Ensembl Cavefish
Match: pde10a (phosphodiesterase 10A [Source:ZFIN;Acc:ZDB-GENE-040426-1115])

HSP 1 Score: 337.035 bits (863), Expect = 4.362e-101
Identity = 218/598 (36.45%), Postives = 334/598 (55.85%), Query Frame = 1

Query: 1087 TNIKWNSFLCVPIINQSDGCVSALVCMINKIGSNQSFTAEDISITQHLFQYTAAVLTSSVAF---QMERRLKIQTET---MLQVAMNIFRKLGDLTGLLKEIMTEAKKLTNAERCSVFLVDNDTKELVSKVFDGLPTISEQSQ-HPV-----EIRIPVTQGVAGRVATTGEMLNIVDAYSHPLFYRGVDEETGYKTRNILCFPIKDENEKVVGVAQLCNKINGPCFTNYDEDIAKAFSVYCCISIMHSLMYKKVQDAQHRNKLANELMIYHMQVNEDTVKWLTSCGYPDLMDIKEDFNSFECIPRDIKEHDSALAVLGMFNTLGFISKWRLSRPTLSRFILMIKRGYRDPPYHNWTHAFSVAHFIYLCITNLPLHGQLLPIELLALFVASLCHDIDHRGTNNSFQVTSKSVLAALYSSEGSVLERHHFSQTICVLNSEGCNIFENFSRQDYHHVLDLIRDIILATDLAHHLRIISDQRKMIDT-FYDSNSNHHHVLLMDLLMTSADLSDQSKNWKNTRAVAQLIYEEFFSQGDMEKSIGQKPAEQMDRERAC-VPSLQMSFLDGIALPCFQLFADLYPLFGQKMIENITNNRKKWEKL 2838
            + I+ +S LC+PI+       +A+  +I  +  ++    E  +++ H    TA +  +SVA    Q+ R L  QTE    +L V+   F  +  +  LL+ IM  AK L NA+RC++F VD++ KEL S +FD    I E+++  PV     EIR  + +G+AG+VA TGE+LNI DAY+ P F R VD  TGY TRNILC PI      V+GV Q+ NK++G  FT  DE+  K F+V+C +++  + MY +++ ++   ++  E + YH     +  K LT    PD +  + +   F+  P +  E   A+ V  + N+ G  S + L +  L RF + +++ YR  PYHNW HA +VAH +Y  +      G    +E   L +A LCHD+DHRG +NS+       LAALYS+  S +E+HHFSQT+ +L  EG NIF N +  +Y  VL++IR  I+ATDLA +        +++ T   D N++ H   ++ L+MT+ DL   +K W  TR  A  IY EF+S+GD  K IG +P   MDR++   VP  Q+ F + +A+PC+    +L+P     ++     N  +WEK+
Sbjct:  214 SGIRVHSVLCLPIL-------TAIGDLIAVLELHRHLGQEPFNLS-HQEVATANLAWASVAIHQVQVCRGLAKQTELNDFLLDVSKTYFDNIVAIDSLLEHIMIYAKNLVNADRCALFQVDHNNKELYSDLFD----IGEENEGKPVFRKTKEIRFSIEKGIAGQVARTGEVLNIPDAYADPRFNREVDHYTGYTTRNILCMPIVSRG-TVIGVVQMVNKLSGSAFTKTDENNFKMFAVFCALALHCANMYHRIRHSECIYRVTMEKLSYHSICTSEEWKTLTQLSLPDPIYKEIELFHFDISPYE--ELWPAVFVYMIHNSCG-KSSFELEK--LCRFTMSVRKNYRRVPYHNWKHAVTVAHCMYAILQK--TSGIFTELEKKGLLIACLCHDLDHRGYSNSYLQKFDHPLAALYST--STMEQHHFSQTVSILQ-EGHNIFSNLTSSEYEQVLEIIRKAIIATDLALYFGNRKQIAELLSTGALDLNNHAHRDRVIGLMMTACDLCSVTKLWPVTRLTANDIYAEFWSEGDEMKKIGMQPIPMMDRDKKDEVPQGQVGFYNAVAIPCYTTLVELFPP-SAPLLSACRENLGQWEKI 787

[Close]

BLAST of Phosphodiesterase vs. Ensembl Cavefish
Match: pde11al (dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A-like [Source:NCBI gene;Acc:103024879])

HSP 1 Score: 323.553 bits (828), Expect = 2.946e-95
Identity = 196/618 (31.72%), Postives = 332/618 (53.72%), Query Frame = 1

Query: 1048 NMFQDKL--NELELLTNIKWNSFLCVPIINQSDGCVSALVCMINKIGSNQSFTAEDISITQHLFQYTAAVLTSSVAFQMERRLKIQTETMLQVAMNIFRKLGDLTGLLKEIMTEAKKLTNAERCSVFLVDNDTKELV--SKVFDGLPTISEQSQHPVEIRIP-----VTQGVAGRVATTGEMLNIVDAYSHPLFYRGVDEETGYKTRNILCFPIKDENEKVVGVAQLCNKINGPCFTNYDEDIAKAFSVYCCISIMHSLMYKKVQDAQHRNKLANELMIYHMQVNEDTVKWLTSCGYPDLMDIKED---FNSFECIPRDIKEHDSAL-AVLGMFNTLGFISKWRLSRPTLSRFILMIKRGYRDPPYHNWTHAFSVAHFIYLCITNLPLHGQLLPIELLALFVASLCHDIDHRGTNNSFQVTSKSVLAALYSSEGSVLERHHFSQTICVLNSEGCNIFENFSRQDYHHVLDLIRDIILATDLAHHLRIISDQRK------MIDTFYDSNSNHHHVLLMDLLMTSADLSDQSKNWKNTRAVAQLIYEEFFSQGDMEKS-IGQKPAEQMDRERA-CVPSLQMSFLDGIALPCFQLFADLYPLFGQKMIENITNNRKKWEKL 2838
            N ++D    +E++ LT  K  S LC+ I N SDG V  +V  INK      FT +D  + Q    +    ++++  F   R+   ++  +L+V  ++F +  DL  ++++IM  A  L   ERCSV L+++    +V  SK F+ +  +          ++      +   +A  VA+TG  +NI D    P F    D+ +G+  R++LC PI +   +++GVAQ+ N+++   F + D+ + +AF ++C + I +++MY +V+    +  +A +++ YH   ++  V  L +   P   ++  D   FN F        ++D+ + A L MF  LG + K+++    L R++L +++ YR   YHNW HAF+V+  +++ IT       L   E LAL V  LCHD+DHRGTNN+FQ  S S LA LY +  + LE HHF+  + +L SEG NIF N   ++Y H++ L++  IL+TDL  +      QR+      ++   +  +   H  +L  +LMT+ DL   ++ W+ ++ VA+L+  EFF QGD E++ +   P+   DR R   +P+LQ+ ++DGI  P ++    L     Q M++ I  NRKKWE+L
Sbjct:  254 NAYEDHRFSDEIDKLTGYKTQSILCMAICN-SDGEVIGVVQAINKNPKGTPFTEDDEKVLQMYLPFCGISISNAKLFSESRKEYDRSRALLEVVNDLFEEQTDLEKIVRKIMQRALTLLQCERCSVLLLEDIHSPVVKFSKTFELMSPLCSVDHDISMEKVSCSDWLINNSIAELVASTGLPVNISDVCQDPRFDAEADQASGFHIRSVLCVPIWNRTHQIIGVAQILNRLDRKTFNDADQRLFEAFVIFCGLGINNTMMYNQVKKTWAKQSVALDMLSYHATCSKVEVDRLKAAKIPLSSELGIDKFHFNDFSL------DNDAMITASLRMFLELGVVQKFKIDYEVLCRWLLTVRKNYRTVAYHNWRHAFNVSQCMFVMITTAGFQEVLTDTETLALMVGCLCHDLDHRGTNNAFQAKSGSALALLYGTSAT-LEHHHFNHAVMILQSEGHNIFANLCSKEYSHMMQLLKQAILSTDLTLYF-----QRRTKFFECVLSGEFSWSIQEHRDVLRSMLMTACDLGAVTRPWEISKQVAELVTSEFFEQGDRERAELKLTPSAIFDRNRKDELPALQLEWIDGICKPLYEALVKLNRKL-QPMVDGIDANRKKWEEL 857

HSP 2 Score: 99.7525 bits (247), Expect = 8.237e-21
Identity = 68/206 (33.01%), Postives = 113/206 (54.85%), Query Frame = 1

Query: 1261 SVAFQMERRLKIQTET--MLQVAMNIFRKLGDLTGLLKEIMTEAKKLTNAERCSVFLVDNDT--KELVSKVFD---GLPTISEQSQHPVEIRIPVTQGVAGRVATTGEMLNIVDAYSHPLFYRGVDEETGYKTRNILCFPIKDENEKVVGVAQLCNK-INGPCFTNYDEDIAKAFSVYCCISIMHSLMYKKVQDAQHRNKLANELM 1854
            S A   + RLK   E    L++  +I  +L D+T L  +I+     + +A+RCS+FLV+  +  + LVSK FD   G       S +  E+++P  +G+ G VA  GE +NI +AY    F   +D+ TGYKT++ILC  I + + +V+GV Q  NK   G  FT  DE + + +  +C ISI ++ ++ + +    R++   E++
Sbjct:  142 SSALDYKCRLKENNEREFFLELVKDISNEL-DMTNLSYKILINVCIMVSADRCSLFLVEGPSHKRTLVSKFFDVHSGTTVRPSSSMNSSEVQVPWGKGIIGYVAEHGETVNIPNAYEDHRFSDEIDKLTGYKTQSILCMAICNSDGEVIGVVQAINKNPKGTPFTEDDEKVLQMYLPFCGISISNAKLFSESRKEYDRSRALLEVV 346

[Close]

BLAST of Phosphodiesterase vs. Ensembl Cavefish
Match: pde11al (dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A-like [Source:NCBI gene;Acc:103024879])

HSP 1 Score: 307.375 bits (786), Expect = 6.926e-90
Identity = 185/592 (31.25%), Postives = 319/592 (53.89%), Query Frame = 1

Query: 1048 NMFQDKL--NELELLTNIKWNSFLCVPIINQSDGCVSALVCMINKIGSNQSFTAEDISITQHLFQYTAAVLTSSVAFQMERRLKIQTETMLQVAMNIFRKLGDLTGLLKEIMTEAKKLTNAERCSVFLVDNDTKELV--SKVFDGLPTISEQSQHPVEIRIP-----VTQGVAGRVATTGEMLNIVDAYSHPLFYRGVDEETGYKTRNILCFPIKDENEKVVGVAQLCNKINGPCFTNYDEDIAKAFSVYCCISIMHSLMYKKVQDAQHRNKLANELMIYHMQVNEDTVKWLTSCGYPDLMDIKED---FNSFECIPRDIKEHDSAL-AVLGMFNTLGFISKWRLSRPTLSRFILMIKRGYRDPPYHNWTHAFSVAHFIYLCITNLPLHGQLLPIELLALFVASLCHDIDHRGTNNSFQVTSKSVLAALYSSEGSVLERHHFSQTICVLNSEGCNIFENFSRQDYHHVLDLIRDIILATDLAHHLRIISDQRK------MIDTFYDSNSNHHHVLLMDLLMTSADLSDQSKNWKNTRAVAQLIYEEFFSQGDMEKS-IGQKPAEQMDRERAC-VPSLQMSFLDGIALPCFQL 2760
            N ++D    +E++ LT  K  S LC+ I N SDG V  +V  INK      FT +D  + Q    +    ++++  F   R+   ++  +L+V  ++F +  DL  ++++IM  A  L   ERCSV L+++    +V  SK F+ +  +          ++      +   +A  VA+TG  +NI D    P F    D+ +G+  R++LC PI +   +++GVAQ+ N+++   F + D+ + +AF ++C + I +++MY +V+    +  +A +++ YH   ++  V  L +   P   ++  D   FN F        ++D+ + A L MF  LG + K+++    L R++L +++ YR   YHNW HAF+V+  +++ IT       L   E LAL V  LCHD+DHRGTNN+FQ  S S LA LY +  + LE HHF+  + +L SEG NIF N   ++Y H++ L++  IL+TDL  +      QR+      ++   +  +   H  +L  +LMT+ DL   ++ W+ ++ VA+L+  EFF QGD E++ +   P+   DR R   +P+LQ+ ++DGI  P +++
Sbjct:  254 NAYEDHRFSDEIDKLTGYKTQSILCMAICN-SDGEVIGVVQAINKNPKGTPFTEDDEKVLQMYLPFCGISISNAKLFSESRKEYDRSRALLEVVNDLFEEQTDLEKIVRKIMQRALTLLQCERCSVLLLEDIHSPVVKFSKTFELMSPLCSVDHDISMEKVSCSDWLINNSIAELVASTGLPVNISDVCQDPRFDAEADQASGFHIRSVLCVPIWNRTHQIIGVAQILNRLDRKTFNDADQRLFEAFVIFCGLGINNTMMYNQVKKTWAKQSVALDMLSYHATCSKVEVDRLKAAKIPLSSELGIDKFHFNDFSL------DNDAMITASLRMFLELGVVQKFKIDYEVLCRWLLTVRKNYRTVAYHNWRHAFNVSQCMFVMITTAGFQEVLTDTETLALMVGCLCHDLDHRGTNNAFQAKSGSALALLYGTSAT-LEHHHFNHAVMILQSEGHNIFANLCSKEYSHMMQLLKQAILSTDLTLYF-----QRRTKFFECVLSGEFSWSIQEHRDVLRSMLMTACDLGAVTRPWEISKQVAELVTSEFFEQGDRERAELKLTPSAIFDRNRKDELPALQLEWIDGICKPLYEV 832

HSP 2 Score: 99.7525 bits (247), Expect = 6.788e-21
Identity = 68/206 (33.01%), Postives = 114/206 (55.34%), Query Frame = 1

Query: 1261 SVAFQMERRLKI--QTETMLQVAMNIFRKLGDLTGLLKEIMTEAKKLTNAERCSVFLVDNDT--KELVSKVFD---GLPTISEQSQHPVEIRIPVTQGVAGRVATTGEMLNIVDAYSHPLFYRGVDEETGYKTRNILCFPIKDENEKVVGVAQLCNK-INGPCFTNYDEDIAKAFSVYCCISIMHSLMYKKVQDAQHRNKLANELM 1854
            S A   + RLK   + E  L++  +I  +L D+T L  +I+     + +A+RCS+FLV+  +  + LVSK FD   G       S +  E+++P  +G+ G VA  GE +NI +AY    F   +D+ TGYKT++ILC  I + + +V+GV Q  NK   G  FT  DE + + +  +C ISI ++ ++ + +    R++   E++
Sbjct:  142 SSALDYKCRLKENNEREFFLELVKDISNEL-DMTNLSYKILINVCIMVSADRCSLFLVEGPSHKRTLVSKFFDVHSGTTVRPSSSMNSSEVQVPWGKGIIGYVAEHGETVNIPNAYEDHRFSDEIDKLTGYKTQSILCMAICNSDGEVIGVVQAINKNPKGTPFTEDDEKVLQMYLPFCGISISNAKLFSESRKEYDRSRALLEVV 346

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BLAST of Phosphodiesterase vs. Ensembl Cavefish
Match: pde11a (phosphodiesterase 11a [Source:ZFIN;Acc:ZDB-GENE-070912-207])

HSP 1 Score: 306.22 bits (783), Expect = 3.804e-89
Identity = 189/606 (31.19%), Postives = 324/606 (53.47%), Query Frame = 1

Query: 1069 NELELLTNIKWNSFLCVPIINQSDGCVSALVCMINKIGSNQSFTAEDISITQHLFQYTAAVLTSSVAFQMERRLKIQTETMLQVAMNIFRKLGDLTGLLKEIMTEAKKLTNAERCSVFLVDNDTKELV--SKVFDGL-PTISEQSQHPVEIRIP--------VTQGVAGRVATTGEMLNIVDAYSHPLFYRGVDEETGYKTRNILCFPIKDENEKVVGVAQLCNKINGPCFTNYDEDIAKAFSVYCCISIMHSLMYKKVQDAQHRNKLANELMIYHMQVNEDTVKWLTSCGYPDLMDIKEDFNSFECIPRDIKEHDSAL-AVLGMFNTLGFISKWRLSRPTLSRFILMIKRGYRDPPYHNWTHAFSVAHFIYLCITNLPLHGQLLPIELLALFVASLCHDIDHRGTNNSFQVTSKSVLAALYSSEGSVLERHHFSQTICVLNSEGCNIFENFSRQDYHHVLDLIRDIILATDLAHHLRIISDQRKMIDTFYDSNSNHHHVLLMDLLMTSADLSDQSKNWKNTRAVAQLIYEEFFSQGDMEKS-IGQKPAEQMDRERAC-VPSLQMSFLDGIALPCFQLFADLYPLFGQKMIENITNNRKKWEKLNE 2844
            +E++ LT  K  S LC+PI N SDG +  +   INK      FT +D  + Q    +    ++++  F   R+   ++  +L+V  ++F +  DL  ++++IM  A+ L   ERCSV L+++    +V  +K F+ L P  S  +++  +  +         +   +A  VA+TG  +NI DAY  P F    D+ +G+  R++LC PI + N +++GVAQ+ N+++G  F + D+ + +AF ++C + I +++MY +V+ +  +  +A +++ YH   ++  V    +   P + ++  D  SF+    D+   D+ + A L MF  LG + K+++   TL R++L +++ YR   YHNW HAF+V   ++  +T       L  +E+LAL V  +CHD+DHRGTNN+FQ  + S L+ LY +  + LE HHF+  + +L SE   +          + L +     L +     L   S    +    Y+ N   H  +   +LMT+ DL   +K W  +R VA+L+  EFF QGD E+S +   P+   DR R   +PSLQ+ ++DGI  P ++  A L P   Q M++ I  NR KW++L++
Sbjct:  266 DEIDKLTGYKTKSLLCMPIRN-SDGEIIGVAQAINKSPGGALFTEDDEKVLQMYLPFCGIAISNAQLFAASRKEYDRSRALLEVVNDLFEEQTDLEKIVRKIMHRAQTLLKCERCSVQLLEDIESPVVKFTKSFELLSPKCSADTENSFKDSMEKSSYSDWLINNSIAELVASTGLPVNISDAYQDPRFDAEADQFSGFHIRSVLCVPIWNSNHQIIGVAQVLNRLDGKPFDDADQRLFEAFVIFCGLGINNTIMYDQVKKSWAKQSVALDVLSYHATCSKTEVDKFKAANIPLVCELGIDKLSFDDFSLDV---DAMITAALRMFMELGMLQKFKIDYETLCRWLLTVRKNYRMVLYHNWRHAFNVCQCMFSLLTTAGFQETLSELEILALIVGCVCHDLDHRGTNNAFQAKTGSALSLLYGTSAT-LEHHHFNHAVMILQSEVGTV----------NNLQMFMHSRLHSCFKGQLNRNSFFELVKKGEYNWNVKEHRDMFRSMLMTACDLGAVTKPWDISRKVAELVTSEFFEQGDRERSELKLTPSAIFDRNRKDELPSLQLEWIDGICSPLYETLAKLNPKL-QPMVDVIQANRAKWDELHQ 855

HSP 2 Score: 107.457 bits (267), Expect = 3.269e-23
Identity = 68/209 (32.54%), Postives = 118/209 (56.46%), Query Frame = 1

Query: 1255 TSSVAFQMERRLKIQTETMLQVAMNIFRKLGDLTGLLKEIMTEAKKLTNAERCSVFLVDN--DTKELVSKVFDG------LPTISEQSQHPVEIRIPVTQGVAGRVATTGEMLNIVDAYSHPLFYRGVDEETGYKTRNILCFPIKDENEKVVGVAQLCNK-INGPCFTNYDEDIAKAFSVYCCISIMHSLMYKKVQDAQHRNKLANELM 1854
            +++V F+   +   + E  L++  +I   L DLT L  +I+     + +A+RCS+FLV+   + K LVSK FD       LP++S       E+++P  +G+ G VA  GE +NI DAY    F   +D+ TGYKT+++LC PI++ + +++GVAQ  NK   G  FT  DE + + +  +C I+I ++ ++   +    R++   E++
Sbjct:  146 STAVDFKYYLKEHNEREFFLELVKDISNDL-DLTSLSYKILVFVCIMVDADRCSLFLVEGTANKKTLVSKFFDVHAGTTVLPSLSNSD----EVQVPWGKGIIGYVAEHGETVNIPDAYQDHRFSDEIDKLTGYKTKSLLCMPIRNSDGEIIGVAQAINKSPGGALFTEDDEKVLQMYLPFCGIAISNAQLFAASRKEYDRSRALLEVV 349

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BLAST of Phosphodiesterase vs. Ensembl Sea Lamprey
Match: PDE2A (phosphodiesterase 2A [Source:HGNC Symbol;Acc:HGNC:8777])

HSP 1 Score: 692.575 bits (1786), Expect = 0.000e+0
Identity = 327/589 (55.52%), Postives = 440/589 (74.70%), Query Frame = 1

Query: 1075 LELLTNIKWNSFLCVPIINQSDGCVSALVCMINKIGSNQSFTAEDISITQHLFQYTAAVLTSSVAFQMERRLKIQTETMLQVAMNIFRKLGDLTGLLKEIMTEAKKLTNAERCSVFLVDNDTKELVSKVFDGLPTISEQSQHPVEIRIPVTQGVAGRVATTGEMLNIVDAYSHPLFYRGVDEETGYKTRNILCFPIKDENEKVVGVAQLCNKINGPCFTNYDEDIAKAFSVYCCISIMHSLMYKKVQDAQHRNKLANELMIYHMQVNEDTVKWLTSCGYPDLMDIKEDFNSFECIPRDIKEHDSALAVLGMFNTLGFISKWRLSRPTLSRFILMIKRGYRDPPYHNWTHAFSVAHFIYLCITNLPLHGQLLPIELLALFVASLCHDIDHRGTNNSFQVTSKSVLAALYSSEGSVLERHHFSQTICVLNSEGCNIFENFSRQDYHHVLDLIRDIILATDLAHHLRIISDQRKMIDTFYDSNSNHHHVLLMDLLMTSADLSDQSKNWKNTRAVAQLIYEEFFSQGDMEKSIGQKPAEQMDRERACVPSLQMSFLDGIALPCFQLFADLYPLFGQKMIENITNNRKKWEKLN 2841
            L  L   + NS L VPI+ ++   V  L C+ NK+   QS+T  D    QH F +T+ VLTS++AFQ E++LK + + +LQVA N+F  L D++ LL EI+ EA+ L+NAERCSVFL+D  + ELV+KVFDG   +S++S    E+RIP  QG+AG VATTGE+LNI DAYSHPLFYRGVD+ TG++TR+ILCFPIKDENE+V+GVA+LCNKINGP F+ +DED+A AFS+YC ISI +SL+YKKV +AQ R++L+NE+M+YHM+V+ + +  + +     + DI  DF  F   PR + E  +  A+LGM   +GFI+ ++L   TL+R+ LM+++GYRDPPYHNW HA+SV+HF YL   NL L   L  +E+ ALFV+ LCHD+DHRGTNNSFQV SKSVLAALYSSEGSV+ERHHF+Q I ++NS GCNI EN SR++Y  +LDL+RDIILATDLAHHLRI  D RK+ D  Y+ ++ H H LL+ LLMTS DLSDQ+K WK TR +A+LIY+EFFSQGD+EK++G +P+E MDRE+A +P LQ+SF++ IA+P F+L  D+ P    ++ E +  N++ W +++
Sbjct:    1 LNSLLGFRVNSMLSVPIVARATSQVVTLACVFNKL-HGQSYTETDERKIQHCFCFTSTVLTSTIAFQKEQKLKFECQALLQVAKNLFTHLDDVSVLLHEIIQEARNLSNAERCSVFLLDRSSHELVAKVFDG-GVVSDES---YEVRIPADQGIAGHVATTGEVLNIKDAYSHPLFYRGVDDSTGFRTRSILCFPIKDENEEVIGVAELCNKINGPWFSKFDEDLATAFSIYCGISIANSLLYKKVAEAQQRSQLSNEMMMYHMKVSPEEMNKVLNSRIQTVTDIHPDFAKFTYTPRSLGEDQTITAILGMVEDMGFINNYKLDLRTLTRWCLMVRKGYRDPPYHNWMHAYSVSHFCYLLYKNLDLGKYLQDMEIFALFVSCLCHDLDHRGTNNSFQVDSKSVLAALYSSEGSVMERHHFAQAIAIINSAGCNILENLSRKEYQRMLDLMRDIILATDLAHHLRIFKDLRKIADAGYNPDNGHQHSLLLCLLMTSCDLSDQTKGWKTTRKIAELIYKEFFSQGDLEKAMGNRPSEMMDREKAYIPELQISFMEHIAMPLFKLLKDMLP-GAAELYERVAANKEHWMRVS 583

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BLAST of Phosphodiesterase vs. Ensembl Sea Lamprey
Match: PDE2A (phosphodiesterase 2A [Source:HGNC Symbol;Acc:HGNC:8777])

HSP 1 Score: 496.123 bits (1276), Expect = 1.098e-167
Identity = 233/387 (60.21%), Postives = 299/387 (77.26%), Query Frame = 1

Query: 1348 DLTGLLKEIMTEAKKLTNAERCSVFLVDNDTKELVSKVFDGLPTISEQSQHPVEIRIPVTQGVAGRVATTGEMLNIVDAYSHPLFYRGVDEETGYKTRNILCFPIKDENEKVVGVAQLCNKINGPCFTNYDEDIAKAFSVYCCISIMHSLMYKKVQDAQHRNKLANELMIYHM----QVNEDTVKWLTSCGYPDLMDIKEDFNSFECIPRDIKEHDSALAVLGMFNTLGFISKWRLSRPTLSRFILMIKRGYRDPPYHNWTHAFSVAHFIYLCITNLPLHGQLLPIELLALFVASLCHDIDHRGTNNSFQVTSKSVLAALYSSEGSVLERHHFSQTICVLNSEGCNIFENFSRQDYHHVLDLIRDIILATDLAHHLRIISDQRKMID 2496
            D++ LL EI+ EA+ L+NAERCSVFL+D  + ELV+KVFDG   +S++     E+RIP  QG+AG VATTGE+LNI DAYSHPLFYRGVD+ TG++TR+ILCFPIKDENE+V+GVA+LCNKINGP F+ +DED+A AFS+YC ISI +SL+YKKV +AQ R++L+NE+M+YHM    QV+ + +  + +     + DI  DF  F   PR + E  +  A+LGM   +GFI+ ++L   TL+R+ LM+++GYRDPPYHNW HA+SV+HF YL   NL L   L  +E+ ALFV+ LCHD+DHRGTNNSFQV SKSVLAALYSSEGSV+ERHHF+Q I ++NS GCNI EN SR++Y  +LDL+RDIILATDLAHHLRI  D RK+ D
Sbjct:    6 DVSVLLHEIIQEARNLSNAERCSVFLLDRSSHELVAKVFDG-GVVSDEFMKSYEVRIPADQGIAGHVATTGEVLNIKDAYSHPLFYRGVDDSTGFRTRSILCFPIKDENEEVIGVAELCNKINGPWFSKFDEDLATAFSIYCGISIANSLLYKKVAEAQQRSQLSNEMMMYHMKVGTQVSPEEMNKVLNSRIQTVTDIHPDFAKFTYTPRSLGEDQTITAILGMVEDMGFINNYKLDLRTLTRWCLMVRKGYRDPPYHNWMHAYSVSHFCYLLYKNLDLGKYLQDMEIFALFVSCLCHDLDHRGTNNSFQVDSKSVLAALYSSEGSVMERHHFAQAIAIINSAGCNILENLSRKEYQRMLDLMRDIILATDLAHHLRIFKDLRKIAD 391

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BLAST of Phosphodiesterase vs. Ensembl Sea Lamprey
Match: pde5ab (phosphodiesterase 5A, cGMP-specific, b [Source:ZFIN;Acc:ZDB-GENE-060824-4])

HSP 1 Score: 266.929 bits (681), Expect = 2.546e-76
Identity = 189/642 (29.44%), Postives = 326/642 (50.78%), Query Frame = 1

Query: 1048 NMFQD-KLN-ELELLTNIKWNSFLCVPIINQSDGCVSALVCMINKIGSNQS-FTAEDISITQHLFQYTAAVLTSSVAFQMERRLKIQTETMLQVAMNIFRKLGDLTGLLKEIMTEAKKLTNAERCSVFLVDNDTKELVSKVFDG---LPTISEQSQHPVEIRIPVTQGVAGRVATTGEMLNIVDAYSHPLFYRGVDEETGYKTRNILCFPIKDENE-KVVGVAQLCNKINGPC-----FTNYDEDIAKAFSVYCCISIMHSLMYKKVQDAQHRNKLANELMIYHMQVNEDTV-----KWLTSCGYP-----DLMDIKEDFNSFECIPRDIKEHDSALAVLGMFNTLGFISKWRLSRPTLSRFILMIKRGYR-DPPYHNWTHAFSVAHFIYLCITNLPLHGQLLPIELLALFVASLCHDIDHRGTNNSF-QVTSKSVLAALYSSEGSVLERHHFSQTICVLNSEGCNIFENFSRQDYHHVLDLIRDIILATDLAHHLRIISDQRKMI-DTFYDSNSNHHHVLLMDLLMTSADLSDQSKNWKNTRAVAQLIYEEFFSQGDMEK-SIGQKPAEQMDRE-RACVPSLQMSFLDGIALPCFQLFADLYPLFGQKMIENITNNRKKWEKLNEDIKNGKISANIFQLFH 2892
            N +QD + N E++L+T  K  S LC+PI   + G +  +   INK G+N+  FT +D         +   VL ++  ++       + + +L++A  +  +   L  L+  I+         +RC+VF+ D D+  + S+VF     +P ++E +        PV+   A  V     +LNI D +    F   V+E   Y+T+++LC PI++  + +V+GV QL NK+         F   DE   +AF+++C ++I ++ MY+ V  A  +  +  E++ YH   +ED       + LT+   P     +L+D    F+ F      + E  +A+  L M   L  +  + +      R+IL +++ YR +  YHNW HAF+    ++  +        L P+E+L L +A+L HD+DHRG NNS+ +  S   LA LY    S+LE HHF Q + +LNS G  +  + S Q+Y   + +I   IL+TDLA + +   +   ++ D  ++    HH  LL  ++MT+ D+S  +K W   + +A+L+  EFF QGD E+  +  +P + M+RE R  +P++Q+ F+DGI LP ++  + ++P     ++    +NR+ WEKL      G I   +   +H
Sbjct:  198 NAYQDPRFNVEVDLMTGYKTQSVLCLPI-KDNKGEIVGVAQAINKKGNNEGKFTEKDEREFGAYLAFCGIVLHNAQLYEDSLLENRRNQVLLELASLVCEEQSSLEELVGRIIDIILSFMPCQRCAVFIADKDSPNIFSRVFHKSLEVPGVAENTSQSESRSHPVSFIYAEFVMKMLTLLNIPDVHRDNRFNLPVEERGDYRTKSLLCAPIQNRKKNEVIGVCQLVNKLEEGAGEVRPFNRNDEQFVEAFAIFCGMAIRNTRMYEAVARAVAKQTVTLEVLSYHAIAHEDECAKLQSQHLTTTSVPSAQSLNLLDFT--FSDF-----GMAEELTAVGSLRMLLDLSLLQTFSIPNEVACRWILSVRKNYRRNIAYHNWRHAFNTGQCMFTVLVTGQAQNVLTPLEMLCLIIAALSHDLDHRGFNNSYIKNRSDHPLATLYGH--SMLEHHHFDQCLMLLNSPGNEMLSSLSVQEYRSAVGMIEHAILSTDLATYCKNRGEFFSLVKDRTFNLEDQHHRKLLRAMMMTACDVSAITKPWPVQQKIAELVASEFFDQGDRERQELHVEPTDMMNREKRDKIPTIQVGFIDGICLPLYEALSCVFPACA-PLLSGCQSNRQNWEKLTTS-PQGTIVKGVHARWH 827

HSP 2 Score: 102.449 bits (254), Expect = 1.810e-22
Identity = 68/191 (35.60%), Postives = 106/191 (55.50%), Query Frame = 1

Query: 1297 QTETMLQVAMNIFRKLGDLTGLLKEIMTEAKKLTNAERCSVFLVDNDTKE---LVSKVFD-GLPTISEQSQHPVEIRIPVTQGVAGRVATTGEMLNIVDAYSHPLFYRGVDEETGYKTRNILCFPIKDENEKVVGVAQLCNKI--NGPCFTNYDEDIAKAFSVYCCISIMHSLMYKKVQDAQHRNKLANEL 1851
            + E  L++  +I  +L D+  L   I+    ++  A+RCS+F+V  D+ +   LVS +FD  L +  EQ++    +R+   +G+ G VA TG  +NI +AY  P F   VD  TGYKT+++LC PIKD   ++VGVAQ  NK   N   FT  DE    A+  +C I + ++ +Y+       RN++  EL
Sbjct:  102 ERERFLELVKDIACRL-DVVTLCHRILLHVNQVLTADRCSLFIVREDSSQERCLVSTLFDVSLGSTPEQARTSW-LRLAWGKGIVGYVAATGNGVNIPNAYQDPRFNVEVDLMTGYKTQSVLCLPIKDNKGEIVGVAQAINKKGNNEGKFTEKDEREFGAYLAFCGIVLHNAQLYEDSLLENRRNQVLLEL 290

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BLAST of Phosphodiesterase vs. Ensembl Sea Lamprey
Match: pde10a (phosphodiesterase 10A [Source:ZFIN;Acc:ZDB-GENE-040426-1115])

HSP 1 Score: 144.436 bits (363), Expect = 3.502e-37
Identity = 91/279 (32.62%), Postives = 143/279 (51.25%), Query Frame = 1

Query: 1105 SFLCVPIINQSDGCVSALVCMINKIGSNQSFTAEDISITQHLFQYTAAVLTSSVAFQMERRLKIQTET---MLQVAMNIFRKLGDLTGLLKEIMTEAKKLTNAERCSVFLVDNDTKELVSKVFD------GLPTISEQSQHPVEIRIPVTQGVAGRVATTGEMLNIVDAYSHPLFYRGVDEETGYKTRNILCFPIKDENEKVVGVAQLCNKINGPCFTNYDEDIAKAFSVYCCISIMHSLMYKKVQDAQHRNKLANELMIYHMQVNEDTVKWLTSCGYP 1914
            S LC+P+I  +   +  L   + +    + FT     +   L  + +  +      Q+   L  QTE    +L V+   F  +  +  LL+ IM  AK L NA+RC++F VD+   EL S +FD      G P   +  +  +  R  + +G+AG+VA TG +LNI DAY+ P F R VD  TGY TRNILC PI      V+GV Q+ NK++G  FT  DE+  K F+V+C +++  + MY +++ ++   ++  E + YH     +  + L  C  P
Sbjct:  134 SVLCLPLITANGDLLGVL--ELQRRWGKEPFTIRHQEVATALLAWASVAIHQ---VQVSHGLAKQTELNDFLLDVSKTYFDNIVAIDSLLEHIMIYAKNLVNADRCALFQVDHKNNELYSDLFDIGEEKEGQPVFRKTKE--ITCRFSIEKGIAGQVAKTGMVLNIPDAYADPRFNREVDLYTGYTTRNILCMPIVSRG-SVIGVVQMVNKLSGSAFTKTDENNFKMFAVFCALALHCANMYHRIRHSECIFRVTLEKLSYHSVCTAEESQSLMQCTLP 404

[Close]

BLAST of Phosphodiesterase vs. Ensembl Sea Lamprey
Match: PDE1C (phosphodiesterase 1C [Source:HGNC Symbol;Acc:HGNC:8776])

HSP 1 Score: 128.257 bits (321), Expect = 1.101e-31
Identity = 89/292 (30.48%), Postives = 139/292 (47.60%), Query Frame = 1

Query: 1975 EHDSALAVLGMFNTLGFISKWRLSRPTLSRFILMIKRGY--RDPPYHNWTHAFSVAHFI-YLCITNLPLHGQLLPIELLALFVASLCHDIDHRGTNNSFQVTSKSVLAALYSSEGSVLERHHFSQTICVLNS-EGCNIFENFSRQDYHHVLDLIRDIILATDLAHHLRIISDQRKMIDTFYDSNSNHHHVLLMDLLMTSADLSDQSKNWKNTRAVAQLIYEEFFSQGDMEKSIGQKPAEQMDRERACVPSLQMSFLDGIALPCFQLFADL-----YPLFGQKMIENITNNRK 2823
            EH     V  +F     I+++++   ++  F+  ++ GY     PYHN  HA  V   + YL +    +H  L  +E+L++  A+  HD +H GT N+F + ++S  A LY ++ SVLE HH S    ++   E  NI  N S+ D+  +  L+ + +LATD++ H      Q K I               M L++ +AD+S  +KNW   R     + EEFF QGD E  +G   +   DR    VP  Q+ F+D I  P F +  DL      PL  +      T+ R+
Sbjct:  157 EHALKFIVYELFTRYDLIARFKIPVSSVVSFVEALEAGYSKHKNPYHNSVHAADVTQTVHYLMLKTGTIHW-LNELEILSMIFAAAIHDYEHTGTTNNFHIQTRSDSAILY-NDRSVLENHHVSAAYRLMQEDEEMNILINLSKDDWRELRALVVETVLATDMSCHFH----QLKSIKNLLQQPEGVEKPKAMSLMLHTADISHPAKNWNLHRRWTMSLMEEFFRQGDKEAELGLSFSPLCDRNATMVPQSQIGFIDYIVEPTFTVLTDLSEFVVAPLIDEAARAGTTSFRR 442

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BLAST of Phosphodiesterase vs. Ensembl Yeast
Match: PDE2 (High-affinity cyclic AMP phosphodiesterase; component of the cAMP-dependent protein kinase signaling system, protects the cell from extracellular cAMP, contains readthrough motif surrounding termination codon [Source:SGD;Acc:S000005887])

HSP 1 Score: 47.3654 bits (111), Expect = 9.368e-6
Identity = 49/176 (27.84%), Postives = 81/176 (46.02%), Query Frame = 1

Query: 2104 YHNWTHAFSVAHFIYLCITNLPLHGQLLPIELLALFVASLCHDIDHRGTNNSFQVTSKSVLAALYSSEGSVLERHHFSQTICVLNSEGCNIFENFSRQDYHHVLDLIRDIILATDLAHHLRIISDQRKMIDTFYDSNSNHHHVLLMDLLMTSADLSDQSKNWKNTRAVAQLIYEEF 2631
            +HN+ HA  V    +   T L       P++ L L +A++ HD+ H GTNN      +S +A  + +  S+LE  H  +    L SE      + S++ +    D I + ILATD+A H        +  D     N     + L+ L++ +AD+S+ ++    +   A LI  EF
Sbjct:  264 FHNFRHAIDVMQATWRLCTYLLKDN---PVQTLLLCMAAIGHDVGHPGTNNQLLCNCESEVAQNFKN-VSILENFH-RELFQQLLSEHWPQLLSISKKKF----DFISEAILATDMALH-------SQYEDRLMHENP-MKQITLISLIIKAADISNVTRTLSISARWAYLITLEF 422

[Close]

BLAST of Phosphodiesterase vs. Ensembl Nematostella
Match: EDO38644 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SC93])

HSP 1 Score: 496.893 bits (1278), Expect = 1.579e-166
Identity = 245/481 (50.94%), Postives = 340/481 (70.69%), Query Frame = 1

Query: 1411 CSVFLVDNDTKELVSKVFDG-LPTISEQSQHPVEIRIPVTQGVAGRVATTGEMLNIVDAYSHPLFYRGVDEETGYKTRNILCFPIKDENEKVVGVAQLCNKINGPCFTNYDEDIAKAFSVYCCISIMHSLMYKKVQDAQHRNKLANELMIYHMQVNEDTVKWLTS--CGYPDLMDIKEDFNSFECIPRDIKEHDSALAVLGMFNTLGFISKWRLSRPTLSRFILMIKRGYRDPPYHNWTHAFSVAHFIYLCITNLPLHGQLLPIELLALFVASLCHDIDHRGTNNSFQVTSKSVLAALYSSEGSVLERHHFSQTICVLNSEGCNIFENFSRQDYHHVLDLIRDIILATDLAHHLRIISDQRKMIDTFYDSNSNHHHVLLMDLLMTSADLSDQSKNWKNTRAVAQLIYEEFFSQGDMEKSIGQKPAEQMDRERACVPSLQMSFLDGIALPCFQLFADLYPLFGQKMIENITNNRKKWEKLNE 2844
            CS+FL+D +  ELV+KVFDG +P+    +Q   ++RIP  QG+ G+VA TG++LNI DAY+HPLFYRG+D +TG+KTRNILCFPIKD+ + V+GVA+LCNK NG CFT +DED+ +AF++YC ISI HS++YK+   A HR+++ +ELMIYHM V+E+ ++ LT+     PD  +I   F+ F   PR I+  ++  A L MF+ LG I +W++ R TL RF LM+++GYRDPPYHNWTHAF+VAHF YL + N  +  +L  IE +ALFVA LCHD+DHRGTNN+FQV+S S LAALYSSEGSV+ERHHF+QT+C+LNS GCNIF+N +  ++  VLDLIR IILATDL+HHLRI+ D   M     + N     + L+  ++ + DLS   +  K+   +A+   +   S    EK +G  P E MDRERAC+P LQ+ FL+ IALP +++  +L P   +++I+ +  N + W+ + E
Sbjct:    1 CSLFLLDRERDELVAKVFDGEIPS----NQASRDLRIPTNQGIVGQVAMTGKLLNIKDAYTHPLFYRGLDVKTGFKTRNILCFPIKDD-DGVIGVAELCNKANGKCFTKFDEDLTRAFAIYCGISIFHSMLYKRAATAWHRSQVCSELMIYHMHVSEEELQRLTAHEISSPD-EEIPHGFDKFSFAPRTIQMEETVRAALYMFDDLGIIDRWKIPRDTLIRFTLMVRKGYRDPPYHNWTHAFTVAHFCYLLLKNSHMESKLQDIERMALFVACLCHDLDHRGTNNAFQVSSNSTLAALYSSEGSVMERHHFAQTVCILNSSGCNIFKNLTESEFEKVLDLIRYIILATDLSHHLRILKDINNMAKG-RNKNEFEKVLDLIRYIILATDLSHHLRILKDINNMAKGRNKNVPSL--FEKVMGFTPMEMMDRERACIPKLQIDFLENIALPVYKVLHELLPE-TKEVIDTVHKNMECWQAIEE 471

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BLAST of Phosphodiesterase vs. Ensembl Nematostella
Match: EDO44626 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RVE3])

HSP 1 Score: 347.821 bits (891), Expect = 1.315e-107
Identity = 210/572 (36.71%), Postives = 325/572 (56.82%), Query Frame = 1

Query: 1105 SFLCVPIINQSDGCVSALVCMINKIGSNQSFTAEDISI-TQHLFQYTAAVLTSSVAFQMERRLKIQTETMLQVAMNIFRKLGDLTGLLKEIMTEAKKLTNAERCSVFLVDNDTKELVSKVFD--GLPTISEQSQHPVEIRIPVTQGVAGRVATTGEMLNIVDAYSHPLFYRGVDEETGYKTRNILCFPIKDENEKVVGVAQLCNKINGP---CFTNYDEDIAKAFSVYCCISIMHSLMYKKVQDAQHRNKLANELMIYHMQVNEDTVKWLTSCG----YPDLMDIKEDFNSF--ECIPRDIKEHDSALAVLGMFNTLGFISKWRLSRPTLSRFILMIKRGYRDPPYHNWTHAFSVAHFIYLCITNLPLHGQLLPIELLALFVASLCHDIDHRGTNNSFQVTSKSVLAALYSSEGSVLERHHFSQTICVLNSEGCNIFENFSRQDYHHVLDLIRDIILATDLAHHLRIISDQRKMID-TFYDSNSNHHHVLLMDLLMTSADLSDQSKNWKNTRAVAQLIYEEFFSQGDMEKSIGQKPAEQMDRERAC-VPSLQMSFLDGIALPCFQLFADLYP 2778
            S LC PI+ QS+G +   + +   +G +  F  ED  +   +L     ++  + +   M +  K+ TE +L V  +IF+ +  +  ++ +IM  A+ L +A+R S+FLVDN T EL +++FD  G    S  SQ   EIR P T+GVAG VAT+GE LNI DAY    F R +D +TGY TR +LC PI      ++GV Q+ NK +G    CF++ DE   + F++YC +++ H+ +Y K++ ++ ++++A E++ YH + +E  +  L        YPDL   + D  S   E +P+           L +F T    S  R     L RF+L +++ YR  PYHNWTHAF+VAH +YL I +   H     +E LA+F A LCHD+DHRG  NS+     + LAA+YS+  S +E HHF+QTI +L  EG NIF   +  +Y  VL  +++ ILATDLA      +  + ++D   +  +   H  LL  + MT+ DLS  +K W+    + ++IY+EF+++GD+EK+ G++P    DR  A  +P+ Q+ FL GI LPC++L   + P
Sbjct:   55 SILCQPIV-QSNGELVGTIELSRMVGRD-PFDEEDEEVFNSYLVWGGISLYYAEMYLHMHKHRKL-TEFLLNVTRSIFQDIVSMDTVIMKIMNYAQTLVDADRTSLFLVDNKTNELYARIFDIGGSLEDSRSSQLQKEIRFPKTKGVAGYVATSGETLNISDAYHDDRFNREIDIQTGYTTRTLLCMPIFIRG-NIIGVVQMVNKKSGVLIMCFSS-DEKSFQTFAIYCGLALHHAKLYDKIRRSEQKHRVALEVLSYHSKCSEGELHRLKELDCPDPYPDLETYEFDSYSLDSEVMPK-----------LVIFQTRNLFSLSRFDLDELYRFVLTVRKNYRKVPYHNWTHAFAVAHCMYLVIRS--GHNNFTGLEALAMFFACLCHDLDHRGRTNSWMKNEGTPLAAVYST--STMEHHHFNQTITILQHEGHNIFSQLNSAEYKTVLGYMKECILATDLALFFGNKAKLKDVVDKGTFSWDDQEHRRLLRAICMTACDLSACTKPWRIQYKIVEVIYQEFYAEGDLEKAQGKQPIPMKDRNTAHELPAHQVGFLVGICLPCYELLGKVIP 606

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BLAST of Phosphodiesterase vs. Ensembl Nematostella
Match: EDO39522 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S9Q1])

HSP 1 Score: 339.732 bits (870), Expect = 2.150e-102
Identity = 211/625 (33.76%), Postives = 338/625 (54.08%), Query Frame = 1

Query: 1048 NMFQDKL--NELELLTNIKWNSFLCVPIINQSDGCVSALVCMINKIG--SNQSFTAEDISITQHLFQYTAAVLTSSVAFQMERRLKIQTETMLQVAMNIFRKLGDLTGLLKEIMTEAKKLTNAERCSVFLVDNDTKELVSKVFDGLPT---ISEQSQHPVEIRIPVTQGVAGRVATTGEMLNIVDAYSHPLFYRGVDEETGYKTRNILCFPIKDENEKVVGVAQLCNKINGPCFTNYDEDIAKAFSVYCCISIMHSLMYKKVQDAQHRNKLANELMIYH--------MQVNEDTVKWLTSCGYPDLMDIKEDFNSFECIPRDIKEHDSALAVLGMFNTLGFISKWRLSRPTLSRFILMIKRGYRDPPYHNWTHAFSVAHFIYLCITNLPLHGQLLPIELLALFVASLCHDIDHRGTNNSFQVTSKSVLAALYSSEGSVLERHHFSQTICVLNSEGCNIFENFSRQDYHHVLDLIRDIILATDLAHHLRIISDQRKMIDTF-YDSNSNHHHVLLMDLLMTSADLSDQSKNWKNTRAVAQLIYEEFFSQGDMEK-SIGQKPAEQMDRERAC-VPSLQMSFLDGIALPCFQLFADLYPLFGQKMIENITNNRKKWEKLNEDIKNGKIS 2868
            N ++D     E++  T     S LC+PI +  DG V  +  +INK G  ++ +FT +D  I      +    + ++  ++  +    + + +L +A  IF +   L  ++ +IM   + L   ERCSV LVD  +K L ++ FD        ++     VE+R P+  G+ G VATTGE LNI DAY+   F   VD+ +G+ T+ ILC PIK+ +  ++GV QL NK++G  F   DE++ +AF+++C ++I  ++MY+ V  A  + K+A E++ YH        +++ E+ +  +TS     L+D   D  S       I + D+    L M   L  +  +++   TL RF+L IK+ YR   YHNW HAF+VA  +Y  +    +      IE  AL VA L HD+DHRGTNNSFQ+ S + LA LYS+  S +E HHF Q I ++NS+G  IF   S  +Y+ ++ L+   I+ATDLA + +   D  K ++    D + +    LL  ++MT+ DLS  +K W   +  A L+ EEFF QGD+E+  +   P   MDR +   +P +Q+ F+D + LP ++ F+       + + +    NR++W+KL ED K  ++S
Sbjct:  215 NAYEDARFNKEIDKKTGYTTRSILCMPIKDH-DGEVIGVAQVINKTGKSTDSAFTIDDEQIFLKYLVFCGIGINNAELYERAQLEIRRNQVLLDLARTIFEEQTSLHNIVHKIMMITQSLLQCERCSVLLVDPTSKTLFAQAFDLEAKDYLQNDDDDKTVEVRFPINIGITGHVATTGETLNIPDAYADERFDPTVDQVSGFTTKTILCMPIKNASGDIIGVVQLLNKVDGTPFNKNDENLFEAFAIFCGMAIHSTVMYENVNKAMAKRKVALEVLSYHAVSPLEEAIKLKEEPLPPITSLR---LIDFAFDDMS-------ISDDDTLKGCLAMLCDLKIVETFQIDYLTLCRFVLTIKKNYRPVMYHNWRHAFNVAQTMYAMLKKPSIGKYFTVIEQYALIVACLSHDLDHRGTNNSFQIKSATPLAQLYST--STMEHHHFDQCIMIINSQGNEIFNTLSADEYNKIIKLLEASIIATDLALYFQRRGDFFKKVENRELDWSDDSSKDLLRAMMMTACDLSAITKPWLVQKRTAHLVAEEFFQQGDLEQEELHSTPLPTMDRRKKDELPQMQVGFIDAVCLPLYKAFSQFDDNL-KVLKDGCRENRRQWQKLAEDHKAREVS 825

HSP 2 Score: 117.857 bits (294), Expect = 5.219e-27
Identity = 75/195 (38.46%), Postives = 109/195 (55.90%), Query Frame = 1

Query: 1285 RLKIQTETMLQVAMNIFRKLG---DLTGLLKEIMTEAKKLTNAERCSVFLVDNDTKE---LVSKVFD-GLPTISEQSQHPVEIRIPVTQGVAGRVATTGEMLNIVDAYSHPLFYRGVDEETGYKTRNILCFPIKDENEKVVGVAQLCNKIN---GPCFTNYDEDIAKAFSVYCCISIMHSLMYKKVQDAQHRNKL 1839
            RL++Q     +V M + + +    D+  L  +I+     L NA+RCS+FL     +    LVSKVFD    +  E  Q   EIRIP   G+ G VA TGE +NI +AY    F + +D++TGY TR+ILC PIKD + +V+GVAQ+ NK        FT  DE I   + V+C I I ++ +Y++ Q    RN++
Sbjct:  110 RLELQQLDEKEVLMELVKDISNDLDVQSLCHKILQNVSILLNADRCSLFLCQGPKEGPRFLVSKVFDVNAESKLEDVQCLEEIRIPWGTGIVGYVAETGETVNIPNAYEDARFNKEIDKKTGYTTRSILCMPIKDHDGEVIGVAQVINKTGKSTDSAFTIDDEQIFLKYLVFCGIGINNAELYERAQLEIRRNQV 304

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BLAST of Phosphodiesterase vs. Ensembl Nematostella
Match: EDO32088 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SW30])

HSP 1 Score: 322.013 bits (824), Expect = 3.526e-98
Identity = 203/567 (35.80%), Postives = 319/567 (56.26%), Query Frame = 1

Query: 1105 SFLCVPIINQSDGCVSALVCMINKIGSNQSFTAEDISI-TQHLFQYTAAVLTSSVAFQMERRLKIQTETMLQVAMNIFRKLGDLTGLLKEIMTEAKKLTNAERCSVFLVDNDTKELVSKVFD-GLPTISEQSQHPVEIRIPVTQGVAGRVATTGEMLNIVDAYSHPLFYRGVDEETGYKTRNILCFPIKDENEKVVGVAQLCNKINGPCFTNYDEDIAKAFSVYCCISIMHSLMYKKVQDAQHRNKLANELMIYHMQVNE-DTVKWLTSCGYPDLMDIKEDFNSFECIPRDIKEHDSALAVLGMFNTLGFISKWRLSRPTLSRFILMIKRGYRDPPYHNWTHAFSVAHFIYLCITNLPLHGQLLPIELLALFVASLCHDIDHRGTNNSFQVTSKSVLAALYSSEGSVLERHHFSQTICVLNSEGCNIFENFSRQDYHHVLDLIRDIILATDLAHHLRIISDQRKMIDTFYDSNS-----NHHHVLLMDLLMTSADLSDQSKNWKNTRAVAQLIYEEFFSQGDMEKSIGQKPAEQMDRERA-CVPSLQMSFLDGIALPCFQLFADLYP 2778
            S LC PII QSDG +  +V ++  +GS   F  ED  I   +L   + A+  + ++ Q+ ++  + T  +L V  +IF ++  +  ++++IM  AKKL NA+RCS+FL+D  ++EL + +FD G    S +  +  EIR PV++G+AG VA TG +LNI DAY    F R VD +TGY T  ILC P++ +   ++GV Q+ N  NG  F+  D    + F+ YC +++ +S MY  +  AQ ++++A E++ YH   +E +T ++L S    DL+ +   +  F                    + L F+  +R+   T++RF L +++ YRD PYHNW HAFSVAH +++ I +   +  L   E L+LF+A +CHD+DHRG NN+F +  K+ LA LY++  S +E HHF Q + +L SEG N+F     + Y  VL+LI++ I+ATDL     +    +K ++T  ++ +       H  L+  LLMT+ DL   +K W         ++EEF+ QGD E+ +G  P   MDR +   +P  Q+ FL GI  PC+ L  D  P
Sbjct:   60 SVLCQPII-QSDGTLVGVVELVKALGS-MPFEKEDEEILNSYLVWGSIAIHHAEISKQITKQKDLNT-FLLNVVRSIFDEVCTMDTVIEKIMAFAKKLVNADRCSLFLLDQASEELFANLFDDGNEDGSFRCGN--EIRFPVSKGIAGYVACTGSILNIRDAYRDERFNREVDMKTGYTTHTILCVPVRCKG-SIIGVCQMVNSHNG-FFSPNDMQSFEMFAGYCGLALHYSKMYNSLFCAQQKHQVALEVISYHCCASEKETEEFLNS---ADLVMLPPAYYPFS-----------------YLSALIFVLIFRVDLETIARFSLSVRKCYRDIPYHNWCHAFSVAHSLWIVIRD---NKSLTDYEKLSLFIAGICHDVDHRGKNNAFMLHCKTPLANLYTT--STMEWHHFKQGVFILESEGQNVFGQLDAESYRRVLELIQEAIIATDLM----LFFGNKKELETLQENKAFRWEEEKHRSLIRCLLMTACDLCTSAKPWDIQVVAVNKVFEEFYIQGDEERKMGLDPLPMMDRSKHDDLPENQVGFLKGIVRPCYSLLMDFVP 590

HSP 2 Score: 55.8398 bits (133), Expect = 7.859e-8
Identity = 34/109 (31.19%), Postives = 54/109 (49.54%), Query Frame = 1

Query: 1513 RIPVTQG--VAGRVATTGEMLNIVDAYSHPLFYRGVDEETGYKTRNILCFPIKDENEKVVGVAQLCNKINGPCFTNYDEDIAKAFSVYCCISIMHSLMYKKVQDAQHRN 1833
            R P+ +G  VA  VA TGE L I D      F +G+  E      ++LC PI   +  +VGV +L   +    F   DE+I  ++ V+  I+I H+ + K++   +  N
Sbjct:   15 RQPIGKGGTVAAHVAETGERLFIKDILGDERFPKGIGVEGMTTAMSVLCQPIIQSDGTLVGVVELVKALGSMPFEKEDEEILNSYLVWGSIAIHHAEISKQITKQKDLN 123

[Close]

BLAST of Phosphodiesterase vs. Ensembl Nematostella
Match: EDO43657 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RY89])

HSP 1 Score: 286.96 bits (733), Expect = 5.395e-84
Identity = 182/602 (30.23%), Postives = 319/602 (52.99%), Query Frame = 1

Query: 1087 TNIKWNSFLCVPIINQSDGCVSALVCMINKIGSNQSFTAEDISITQHLFQYTAAVLTSSVAFQMERRLKIQTETMLQVAMNIFRKLGDLTGLLKEIMTEAKKLTNAERCSVFLVDNDTKELVSKVFDGLPT--ISEQSQHPVEIRIPVTQG---------VAGRVATTGEMLNIVDAYSHPLFYRGVD-EETGYKTRNILCFPIKDENEKVVGVAQLCNKINGPCFTNYDEDIAKAFSVYCCISIMHSLMYKKVQDAQHRNKLANELMIYHMQVNEDTVKWLTSCGYPDLMDIKEDFNSFECIPRDIKEHDSALAVLGMFNTLGFISKWRLSRPTLSRFILMIKRGYRDPPYHNWTHAFSVAHFIYLCITNLPLHGQLLPIELLALFVASLCHDIDHRGTNNSFQVTSKSVLAALYSSEGSVLERHHFSQTICVLNSEGCNIFENFSRQDYHHVLDLIRDIILATDLAHHLRIISDQRKMIDTF-YDSNSNHHHVLLMDLLMTSADLSDQSKNWKNTRAVAQLIYEEFFSQGDMEKS-IGQKPAEQMDRERAC-VPSLQMSFLDGIALPCFQLFADLYPLFGQKMIENITNNRKKWEKLNED 2847
            T     S LC P+ N ++G V  +  +INK      FT ED  +      +    +T++  F++      +   +L++  +IF +   L  ++ +IM  A  L   E+CSV L+        S+VF+   T  I+  +++   I + V++G         VA  VA TG+ +NI DA          + E+ G+    ILC PI++   +++GVA+L N+++   F   DE + +AF+++C + I ++++Y ++  A+ + ++A E++ YH+   +  V+ +     P  +DI  + +SF+     +   D  +A L MF   GFI ++ +    LSR+IL +K  YR+  YHNW HAF+VA  ++  +T   +   +  +E L L V  LCHD+DHRGTNN+FQ  + S L+ LY +  S LE HHF+  + +L++EG   F      +Y  V+  I+  IL+TDLA + +       ++++  +D  +  H  +L  ++MT+ DL+  +K W+  + V  L+  EFF QGDME+     +P   MDR++   +P LQ+ F +   LP F++ A L     Q +++   +N+++W+KL+ +
Sbjct:  132 TGYHTKSLLCKPVKN-NEGEVVGVAQIINKNPGGVPFTKEDEKVCDMYLTFCGIGITNAKLFELSAIEFNRNRALLELVHDIFEEQTSLEKVVHKIMKRALGLLKCEKCSVLLLTQPELRF-SRVFNLKTTGRITSNTRYGF-ILLLVSEGHNDRSFTSRVAKLVAATGKTMNIPDASQDTRLADSSNVEKKGFSP--ILCMPIRNNKFEIIGVAELINRLDNKPFDENDETLFEAFAIFCGLGIHNTMIYDQMARAKAKQQVALEVLSYHVAAKKTEVEKIRDTQVPKAVDI--NLHSFKFDDFSLAADDMLIASLRMFKDCGFIEEFHIDYEVLSRWILTVKNNYRNVIYHNWRHAFNVAQSMFCMLTTGGMASVITKLECLGLIVGCLCHDLDHRGTNNAFQAKTDSPLSKLYGT--STLEHHHFNHAVIILSTEG---FSPILSDEYRQVISYIKHSILSTDLATNFKQRPKFFALVESGEFDPYNMDHRDMLKAMMMTACDLNGTTKPWEIQKEVVNLVTREFFEQGDMERERYNMEPMAIMDRQKIDELPKLQVQFFETTGLPVFKVLAKLNNKL-QPLVDGAESNKRRWQKLDAE 720

HSP 2 Score: 121.709 bits (304), Expect = 2.638e-28
Identity = 74/209 (35.41%), Postives = 114/209 (54.55%), Query Frame = 1

Query: 1264 VAFQMERRLKIQTETMLQVAMNIFRKLG---DLTGLLKEIMTEAKKLTNAERCSVFLVDNDTKE--LVSKVFD------GLPTISEQSQHPVEIRIPVTQGVAGRVATTGEMLNIVDAYSHPLFYRGVDEETGYKTRNILCFPIKDENEKVVGVAQLCNK-INGPCFTNYDEDIAKAFSVYCCISIMHSLMYKKVQDAQHRNKLANELM 1854
            +    E +L ++     +    I R +    DL  L  +I+     LTNA+RCS+FLV+    +  LVSKVFD       + +  E   H  EIR+P+  G+ G  A TGE +NI DAY+ P F + VD++TGY T+++LC P+K+   +VVGVAQ+ NK   G  FT  DE +   +  +C I I ++ +++      +RN+   EL+
Sbjct:    1 MGLNKESKLDLKNSNEREFFFEIVRDIANDLDLKTLSYKILVNVGILTNADRCSLFLVEGPKGKQWLVSKVFDVHIGSLNVSSAKEAIDHQREIRVPLGVGLVGYAAETGETVNIPDAYADPRFNQDVDKQTGYHTKSLLCKPVKNNEGEVVGVAQIINKNPGGVPFTKEDEKVCDMYLTFCGIGITNAKLFELSAIEFNRNRALLELV 209

[Close]

BLAST of Phosphodiesterase vs. Ensembl Medaka
Match: pde11a (phosphodiesterase 11A [Source:NCBI gene;Acc:101163533])

HSP 1 Score: 338.961 bits (868), Expect = 6.863e-101
Identity = 202/625 (32.32%), Postives = 342/625 (54.72%), Query Frame = 1

Query: 1048 NMFQDKL--NELELLTNIKWNSFLCVPIINQSDGCVSALVCMINKIGSNQSFTAEDISITQHLFQYTAAVLTSSVAFQMERRLKIQTETMLQVAMNIFRKLGDLTGLLKEIMTEAKKLTNAERCSVFLVDNDTKELV--SKVFDGL-PTISEQSQHPVEIRIP--------VTQGVAGRVATTGEMLNIVDAYSHPLFYRGVDEETGYKTRNILCFPIKDENEKVVGVAQLCNKINGPCFTNYDEDIAKAFSVYCCISIMHSLMYKKVQDAQHRNKLANELMIYHMQVNEDTVKWLTSCGYPDLMDIKEDFNSFECIPRDIKEHDSAL-AVLGMFNTLGFISKWRLSRPTLSRFILMIKRGYRDPPYHNWTHAFSVAHFIYLCITNLPLHGQLLPIELLALFVASLCHDIDHRGTNNSFQVTSKSVLAALYSSEGSVLERHHFSQTICVLNSEGCNIFENFSRQDYHHVLDLIRDIILATDLAHHLRIISDQRKMIDTF-----YDSNSNHHHVLLMDLLMTSADLSDQSKNWKNTRAVAQLIYEEFFSQGDMEK-SIGQKPAEQMDRERAC-VPSLQMSFLDGIALPCFQLFADLYPLFGQKMIENITNNRKKWEKLNEDIKNG 2859
            + +QD+   +E++ LT  K  S LC+PI N SDG +  +   INK  + + FT +D  + Q    +    ++++  F   R+   ++  +L+V  ++F +  DL  ++++IM  A+ L   ERCSV L+++    +V  +K F+ L P  S  ++   +  +         +   +A  VA+TG  +NI DAY  P F    D+ + +  R++LC PI + N +++GVAQ+ N+++G  F + D+ + +AF ++C + I +++MY +V+ +  +  +A +++ YH   ++  V    +   P + ++  D  SF+    D+   D+ + A L MF  LG + K+++   TL R++L +++ YR   YHNW HAF+V   ++  +T       L  +E+LAL V  +CHD+DHRGTNN+FQ  + S LA LY +  + LE HHF+  + +L SEG NIF N S  +Y  ++ L++  ILATDL  +     + R M         Y+ N   H  +   ++MT+ DL   +K W  +R VA+L+  EFF QGD E+  +   P+   DR R   +P LQ+ ++DGI  P ++    L P   Q M + I  NR KWE+LN+  ++G
Sbjct:  260 DAYQDRRFSDEIDKLTGYKTKSLLCMPIHN-SDGEIIGVAQAINKTSNGELFTEDDEKVLQMYLPFCGIAISNAQLFAASRKEYDRSRALLEVVNDLFEEQTDLEKIVRKIMHRAQTLLKCERCSVQLLEDIESPVVRFTKSFELLSPKCSADAESSFKDSMEKSSYSDWLINNRIAELVASTGLPVNISDAYQDPRFDAEADQFSDFHIRSVLCVPIWNSNHQIIGVAQVLNRLDGKPFDDADQRLFEAFVIFCGLGINNTIMYDQVKKSWAKQSVALDVLSYHATCSKTEVDKFKAANIPLVCELGIDKLSFDDFSLDV---DAMITAALRMFMELGMVQKFKIDYETLCRWLLTVRKNYRMVLYHNWRHAFNVCQCMFAMLTTAGFQEVLTDLEILALIVGCVCHDLDHRGTNNAFQAKTGSALALLYGTSAT-LEHHHFNHAVMILQSEGHNIFSNLSSTEYSDLMQLLKLSILATDLTLYF----ENRNMFFDLVSKGEYNWNVKAHRDMCRSMMMTACDLGAVTKPWDISRKVAELVTSEFFEQGDRERLELKLTPSAIFDRNRKDELPGLQLEWIDGICAPLYETLVKLNPKL-QPMFDRIRANRSKWEELNKKRQSG 874

HSP 2 Score: 106.686 bits (265), Expect = 5.981e-23
Identity = 68/204 (33.33%), Postives = 116/204 (56.86%), Query Frame = 1

Query: 1255 TSSVAFQMERRLKIQTETMLQVAMNIFRKLGDLTGLLKEIMTEAKKLTNAERCSVFLVDN--DTKELVSKVFD-GLPTISEQSQHPVEIRIPVTQGVAGRVATTGEMLNIVDAYSHPLFYRGVDEETGYKTRNILCFPIKDENEKVVGVAQLCNKI-NGPCFTNYDEDIAKAFSVYCCISIMHSLMYKKVQDAQHRNKLANELM 1854
            +++V F+   +   + E  L++  +I   L DLT L  +I+     + +A+RCS+FLV+   + K LVSK FD    T    S +  E+++P  +G+ G VA  GE +NI DAY    F   +D+ TGYKT+++LC PI + + +++GVAQ  NK  NG  FT  DE + + +  +C I+I ++ ++   +    R++   E++
Sbjct:  150 STAVDFKYYLKEHNEREFFLELVKDISNDL-DLTSLSYKILVFVCIMVDADRCSLFLVEGTGNKKTLVSKFFDVHAGTTVLISMNSDEVQVPWGKGIIGYVAEHGETVNIPDAYQDRRFSDEIDKLTGYKTKSLLCMPIHNSDGEIIGVAQAINKTSNGELFTEDDEKVLQMYLPFCGIAISNAQLFAASRKEYDRSRALLEVV 352

[Close]

BLAST of Phosphodiesterase vs. Ensembl Medaka
Match: pde10a (phosphodiesterase 10A [Source:NCBI gene;Acc:101162470])

HSP 1 Score: 334.339 bits (856), Expect = 2.423e-100
Identity = 212/597 (35.51%), Postives = 331/597 (55.44%), Query Frame = 1

Query: 1087 TNIKWNSFLCVPIINQSDGCVSALVCMINKIGSNQSFTAEDISITQHLFQYTAAVLTSSVAF---QMERRLKIQTET---MLQVAMNIFRKLGDLTGLLKEIMTEAKKLTNAERCSVFLVDNDTKELVSKVFDGLPTISEQSQHPV-----EIRIPVTQGVAGRVATTGEMLNIVDAYSHPLFYRGVDEETGYKTRNILCFPIKDENEKVVGVAQLCNKINGPCFTNYDEDIAKAFSVYCCISIMHSLMYKKVQDAQHRNKLANELMIYHMQVNEDTVKWLTSCGYPDLMDIKEDFNSFECIPRDIKEHDSALAVLGMFNTLGFISKWRLSRPTLSRFILMIKRGYRDPPYHNWTHAFSVAHFIYLCITNLPLHGQLLPIELLALFVASLCHDIDHRGTNNSFQVTSKSVLAALYSSEGSVLERHHFSQTICVLNSEGCNIFENFSRQDYHHVLDLIRDIILATDLAHHLRIISDQRKMIDT-FYDSNSNHHHVLLMDLLMTSADLSDQSKNWKNTRAVAQLIYEEFFSQGDMEKSIGQKPAEQMDRERAC-VPSLQMSFLDGIALPCFQLFADLYPLFGQKMIENITNNRKKWEKL 2838
            + I+ +S LC+PI       V+A+  ++  +   + +  E  +++ H    TA +  +SVA    Q+ R L  QTE    +L V+   F  +  +  LL+ IM  AK L NA+RC++F VD++ KEL S +FD      E+   PV     EIR  + +G+AG+VA TGE+LNI DAY+ P F R VD +TGY TRNILC PI      V+GV Q+ NK+ G  FT  DE+  K F+V+C +++  + MY +++ ++   ++  E + YH     +  K LT    P    I ++  +F+      +E   A+ +  + N+ G  S + L +  L RF + +++ YR  PYHNW HA +VAH +Y  +   P       +E   L +A LCHD+DHRG +N++       LAALYS+  S +E+HHFSQT+ +L  EG NIF N +  +Y  VL++IR  I+ATDLA +        +++ T   D N++ H   ++ L+MT+ DL   +K W+ TR  A  IY EF+++GD  K IG +P   MDR++   VP  Q+ F + +A+PC+   + L+P     +++    N   WE++
Sbjct:  191 SGIRVHSVLCLPI-------VTAIGDLVAILELRRHWGKEPFNLS-HQEVATANLAWASVAIHQVQVCRGLAKQTELNDFLLDVSKTYFDNIVAIDSLLEHIMIYAKNLVNADRCALFQVDHNNKELYSDLFD---IGEEKEGKPVFRKTKEIRFSIDKGIAGQVARTGEVLNIPDAYADPRFNREVDLKTGYTTRNILCMPIVSRG-TVIGVVQMVNKLCGSAFTKTDENNFKMFAVFCALALHCANMYHRIRHSECIYRVTMEKLSYHSICTSEEWKTLTQLNLP--TPIYKEIETFQFDISPFEEIWPAVFIYMVHNSCGENS-FELEK--LCRFTMSVRKNYRRVPYHNWKHAVTVAHCMYAILQKTP--DSFTELEKKGLLIACLCHDLDHRGYSNAYLQKFDHPLAALYST--STMEQHHFSQTVSILQLEGHNIFSNLNSSEYEQVLEIIRKAIIATDLALYFNNHQQLTELLSTSALDFNNHSHRDRVIGLMMTACDLCSVTKQWQITRLTANDIYAEFWAEGDEMKKIGIQPIPMMDRDKKDEVPEGQVGFYNSVAIPCYTTLSKLFPP-SSPLLKACRENLSHWERI 765

[Close]

BLAST of Phosphodiesterase vs. Ensembl Medaka
Match: pde10a (phosphodiesterase 10A [Source:NCBI gene;Acc:101162470])

HSP 1 Score: 334.339 bits (856), Expect = 2.702e-100
Identity = 212/597 (35.51%), Postives = 331/597 (55.44%), Query Frame = 1

Query: 1087 TNIKWNSFLCVPIINQSDGCVSALVCMINKIGSNQSFTAEDISITQHLFQYTAAVLTSSVAF---QMERRLKIQTET---MLQVAMNIFRKLGDLTGLLKEIMTEAKKLTNAERCSVFLVDNDTKELVSKVFDGLPTISEQSQHPV-----EIRIPVTQGVAGRVATTGEMLNIVDAYSHPLFYRGVDEETGYKTRNILCFPIKDENEKVVGVAQLCNKINGPCFTNYDEDIAKAFSVYCCISIMHSLMYKKVQDAQHRNKLANELMIYHMQVNEDTVKWLTSCGYPDLMDIKEDFNSFECIPRDIKEHDSALAVLGMFNTLGFISKWRLSRPTLSRFILMIKRGYRDPPYHNWTHAFSVAHFIYLCITNLPLHGQLLPIELLALFVASLCHDIDHRGTNNSFQVTSKSVLAALYSSEGSVLERHHFSQTICVLNSEGCNIFENFSRQDYHHVLDLIRDIILATDLAHHLRIISDQRKMIDT-FYDSNSNHHHVLLMDLLMTSADLSDQSKNWKNTRAVAQLIYEEFFSQGDMEKSIGQKPAEQMDRERAC-VPSLQMSFLDGIALPCFQLFADLYPLFGQKMIENITNNRKKWEKL 2838
            + I+ +S LC+PI       V+A+  ++  +   + +  E  +++ H    TA +  +SVA    Q+ R L  QTE    +L V+   F  +  +  LL+ IM  AK L NA+RC++F VD++ KEL S +FD      E+   PV     EIR  + +G+AG+VA TGE+LNI DAY+ P F R VD +TGY TRNILC PI      V+GV Q+ NK+ G  FT  DE+  K F+V+C +++  + MY +++ ++   ++  E + YH     +  K LT    P    I ++  +F+      +E   A+ +  + N+ G  S + L +  L RF + +++ YR  PYHNW HA +VAH +Y  +   P       +E   L +A LCHD+DHRG +N++       LAALYS+  S +E+HHFSQT+ +L  EG NIF N +  +Y  VL++IR  I+ATDLA +        +++ T   D N++ H   ++ L+MT+ DL   +K W+ TR  A  IY EF+++GD  K IG +P   MDR++   VP  Q+ F + +A+PC+   + L+P     +++    N   WE++
Sbjct:  194 SGIRVHSVLCLPI-------VTAIGDLVAILELRRHWGKEPFNLS-HQEVATANLAWASVAIHQVQVCRGLAKQTELNDFLLDVSKTYFDNIVAIDSLLEHIMIYAKNLVNADRCALFQVDHNNKELYSDLFD---IGEEKEGKPVFRKTKEIRFSIDKGIAGQVARTGEVLNIPDAYADPRFNREVDLKTGYTTRNILCMPIVSRG-TVIGVVQMVNKLCGSAFTKTDENNFKMFAVFCALALHCANMYHRIRHSECIYRVTMEKLSYHSICTSEEWKTLTQLNLP--TPIYKEIETFQFDISPFEEIWPAVFIYMVHNSCGENS-FELEK--LCRFTMSVRKNYRRVPYHNWKHAVTVAHCMYAILQKTP--DSFTELEKKGLLIACLCHDLDHRGYSNAYLQKFDHPLAALYST--STMEQHHFSQTVSILQLEGHNIFSNLNSSEYEQVLEIIRKAIIATDLALYFNNHQQLTELLSTSALDFNNHSHRDRVIGLMMTACDLCSVTKQWQITRLTANDIYAEFWAEGDEMKKIGIQPIPMMDRDKKDEVPEGQVGFYNSVAIPCYTTLSKLFPP-SSPLLKACRENLSHWERI 768

[Close]

BLAST of Phosphodiesterase vs. Ensembl Medaka
Match: pde10a (phosphodiesterase 10A [Source:NCBI gene;Acc:101162470])

HSP 1 Score: 334.724 bits (857), Expect = 3.950e-100
Identity = 212/597 (35.51%), Postives = 331/597 (55.44%), Query Frame = 1

Query: 1087 TNIKWNSFLCVPIINQSDGCVSALVCMINKIGSNQSFTAEDISITQHLFQYTAAVLTSSVAF---QMERRLKIQTET---MLQVAMNIFRKLGDLTGLLKEIMTEAKKLTNAERCSVFLVDNDTKELVSKVFDGLPTISEQSQHPV-----EIRIPVTQGVAGRVATTGEMLNIVDAYSHPLFYRGVDEETGYKTRNILCFPIKDENEKVVGVAQLCNKINGPCFTNYDEDIAKAFSVYCCISIMHSLMYKKVQDAQHRNKLANELMIYHMQVNEDTVKWLTSCGYPDLMDIKEDFNSFECIPRDIKEHDSALAVLGMFNTLGFISKWRLSRPTLSRFILMIKRGYRDPPYHNWTHAFSVAHFIYLCITNLPLHGQLLPIELLALFVASLCHDIDHRGTNNSFQVTSKSVLAALYSSEGSVLERHHFSQTICVLNSEGCNIFENFSRQDYHHVLDLIRDIILATDLAHHLRIISDQRKMIDT-FYDSNSNHHHVLLMDLLMTSADLSDQSKNWKNTRAVAQLIYEEFFSQGDMEKSIGQKPAEQMDRERAC-VPSLQMSFLDGIALPCFQLFADLYPLFGQKMIENITNNRKKWEKL 2838
            + I+ +S LC+PI       V+A+  ++  +   + +  E  +++ H    TA +  +SVA    Q+ R L  QTE    +L V+   F  +  +  LL+ IM  AK L NA+RC++F VD++ KEL S +FD      E+   PV     EIR  + +G+AG+VA TGE+LNI DAY+ P F R VD +TGY TRNILC PI      V+GV Q+ NK+ G  FT  DE+  K F+V+C +++  + MY +++ ++   ++  E + YH     +  K LT    P    I ++  +F+      +E   A+ +  + N+ G  S + L +  L RF + +++ YR  PYHNW HA +VAH +Y  +   P       +E   L +A LCHD+DHRG +N++       LAALYS+  S +E+HHFSQT+ +L  EG NIF N +  +Y  VL++IR  I+ATDLA +        +++ T   D N++ H   ++ L+MT+ DL   +K W+ TR  A  IY EF+++GD  K IG +P   MDR++   VP  Q+ F + +A+PC+   + L+P     +++    N   WE++
Sbjct:  222 SGIRVHSVLCLPI-------VTAIGDLVAILELRRHWGKEPFNLS-HQEVATANLAWASVAIHQVQVCRGLAKQTELNDFLLDVSKTYFDNIVAIDSLLEHIMIYAKNLVNADRCALFQVDHNNKELYSDLFD---IGEEKEGKPVFRKTKEIRFSIDKGIAGQVARTGEVLNIPDAYADPRFNREVDLKTGYTTRNILCMPIVSRG-TVIGVVQMVNKLCGSAFTKTDENNFKMFAVFCALALHCANMYHRIRHSECIYRVTMEKLSYHSICTSEEWKTLTQLNLP--TPIYKEIETFQFDISPFEEIWPAVFIYMVHNSCGENS-FELEK--LCRFTMSVRKNYRRVPYHNWKHAVTVAHCMYAILQKTP--DSFTELEKKGLLIACLCHDLDHRGYSNAYLQKFDHPLAALYST--STMEQHHFSQTVSILQLEGHNIFSNLNSSEYEQVLEIIRKAIIATDLALYFNNHQQLTELLSTSALDFNNHSHRDRVIGLMMTACDLCSVTKQWQITRLTANDIYAEFWAEGDEMKKIGIQPIPMMDRDKKDEVPEGQVGFYNSVAIPCYTTLSKLFPP-SSPLLKACRENLSHWERI 796

[Close]

BLAST of Phosphodiesterase vs. Ensembl Medaka
Match: pde5ab (phosphodiesterase 5A [Source:NCBI gene;Acc:101173207])

HSP 1 Score: 281.567 bits (719), Expect = 1.319e-80
Identity = 192/629 (30.52%), Postives = 320/629 (50.87%), Query Frame = 1

Query: 1072 ELELLTNIKWNSFLCVPIINQSDGCVSALVCMINKI-GSNQSFTAEDISITQHLFQYTAAVLTSSVAFQMERRLKIQTETMLQVAMNIFRKLGDLTGLLKEIMTEAKKLTNAERCSVFLVDNDTKELVSKVF----DGLPTISEQSQHPVEIRIPVTQGVAGRVATTGEMLNIVDAYSHPLFYRGVD--EETGYKTRNILCFPIKD-ENEKVVGVAQLCNKINGPC-----FTNYDEDIAKAFSVYCCISIMHSLMYKKVQDAQHRNKLANELMIYHMQVNEDTVKWLTSCGYPDLMDIKE---DFNSFECIPRDIKEHDSALAVLGMFNTLGFISKWRLSRPTLSRFILMIKRGYRDP-PYHNWTHAFSVAHFIYLCITNLPLHGQLLPIELLALFVASLCHDIDHRGTNNSFQVTSKSVLAALYSSEGSVLERHHFSQTICVLNSEGCNIFENFSRQDYHHVLDLIRDIILATDLAHHLRIISDQRKMIDTFYDSNSN--------HHHVLLMDLLMTSADLSDQSKNWKNTRAVAQLIYEEFFSQGDME-KSIGQKPAEQMDRE-RACVPSLQMSFLDGIALPCFQLFADLYPLFGQ--KMIENITNNRKKWEKLNEDIKNGKISA 2871
            E++L+T  K  S LC+PI N   G V  +   INK  G + +FT +D         ++  VL ++  ++  +    +   +L +A  IF +   L  LL++I         A+ C+VF+ D ++    S VF    + L  + E  +   +++  +    A  V +T + LNI D      F    D  +    + +++LC PI++ + +KV+GV QL NK++        F   DE   +AF+++C + I ++ MY+ V+ A  + ++  E++ YH    E+  + L     P    ++     F+ F     D+ + ++ LA + MF  L  +  +++   +L ++IL +K+ YR    YHNW HAF+ A  ++  + +  L   L  +E+LAL +A+L HD+DHRG NNS+   S+  LA LY    S +E HHF Q + +LN+ G  I    S  +Y   L +I   ILATDLA +++   D       F++   N        HH  LL  +LMT+ D+S  +K W   + VA+L+  EFF QGD E + +  +P + M+RE R  +PS+Q+SF+D I   C QL+  L  L      ++E    NR+ W++L ED + G++ A
Sbjct:  235 EVDLITGYKTQSILCLPIKNHR-GEVVGVAQAINKTCGEDGAFTEQDQKDFSAYLAFSGIVLHNAQLYETSQLENKRNRVLLDLATLIFEEQQCLEVLLRKIAGTILSFMQAQACTVFIADEESMNSFSGVFHMEHEELSEVLEDPKRNCDVK-QINYMFAQYVKSTMQPLNISDVTKDQRFPWTSDCPDHMSNQIKSLLCAPIRNRKKDKVIGVCQLVNKLDEASGSIKSFNRNDEQFLEAFAIFCGLGIQNTQMYETVERAMAKQEVTLEVLSYHASATEEESQELQVATVPSAQSLRLLDFSFSDF-----DLSDTETTLATIRMFTDLNLVQNFQMKYTSLCQWILSVKKNYRKSVAYHNWRHAFNTAQCMFALLKSGRLQNNLSDLEILALMIATLSHDLDHRGVNNSYIQRSEHPLAQLYCH--STMEHHHFDQCLMILNTPGNQILSGLSLDEYKATLKMIEKAILATDLALYMKKRED-------FFELTKNNQFVWVDEHHRDLLRSMLMTACDISAITKPWPVQKRVAELVATEFFEQGDKERRELNIEPTDLMNREKRDKIPSMQVSFIDAI---CIQLYETLAGLLEHCSPLLEGCQKNRQHWKRLAEDCEKGQVDA 844

HSP 2 Score: 100.908 bits (250), Expect = 2.872e-21
Identity = 63/169 (37.28%), Postives = 92/169 (54.44%), Query Frame = 1

Query: 1348 DLTGLLKEIMTEAKKLTNAERCSVFLVDNDT---KELVSKVFDGLPTISEQSQHPVEIRIPVTQGVAGRVATTGEMLNIVDAYSHPLFYRGVDEETGYKTRNILCFPIKDENEKVVGVAQLCNKINGP--CFTNYDEDIAKAFSVYCCISIMHSLMYKKVQDAQHRNKL 1839
            D+  L  +I     +L  A+R S+FLV  D+   K LVS++FD     + +      IR+   +G+ G VA TG+ LNI +AY  P F   VD  TGYKT++ILC PIK+   +VVGVAQ  NK  G    FT  D+    A+  +  I + ++ +Y+  Q    RN++
Sbjct:  145 DVPALCHKIFLHINELIAADRYSLFLVGEDSSNRKFLVSRLFDVAEGSTLEESSSSSIRLEWNKGIVGHVAATGQPLNIKNAYKDPRFNAEVDLITGYKTQSILCLPIKNHRGEVVGVAQAINKTCGEDGAFTEQDQKDFSAYLAFSGIVLHNAQLYETSQLENKRNRV 313

[Close]

BLAST of Phosphodiesterase vs. Planmine SMEST
Match: SMESG000051078.1 (SMESG000051078.1)

HSP 1 Score: 1858.57 bits (4813), Expect = 0.000e+0
Identity = 894/895 (99.89%), Postives = 894/895 (99.89%), Query Frame = 1

Query:  229 MPIACCCLMKRKLSESCLENTERELLLGLSNIVSYEEIPDAVKTTINRVFPNSNSVRLEWINTRENSTKSIRSNGWMNENKIIPQSSLIINRKDRLQEQYSDYFDSENSDNFGIIVPLISSEMKEFQAFLSFSCQEFNQNEKKLLQTFENQVKVMFQRLERLKNSKDSNLQQSNLQDTKLDSSDFYIDSTILSLCADLHDRDPGILQVKIIRFLKQRIHMESAFILTISNNNLELVCQAQDEQIFDPEKRFRVTDSIFERIMKEKICAQLSDVNMFQDKLNELELLTNIKWNSFLCVPIINQSDGCVSALVCMINKIGSNQSFTAEDISITQHLFQYTAAVLTSSVAFQMERRLKIQTETMLQVAMNIFRKLGDLTGLLKEIMTEAKKLTNAERCSVFLVDNDTKELVSKVFDGLPTISEQSQHPVEIRIPVTQGVAGRVATTGEMLNIVDAYSHPLFYRGVDEETGYKTRNILCFPIKDENEKVVGVAQLCNKINGPCFTNYDEDIAKAFSVYCCISIMHSLMYKKVQDAQHRNKLANELMIYHMQVNEDTVKWLTSCGYPDLMDIKEDFNSFECIPRDIKEHDSALAVLGMFNTLGFISKWRLSRPTLSRFILMIKRGYRDPPYHNWTHAFSVAHFIYLCITNLPLHGQLLPIELLALFVASLCHDIDHRGTNNSFQVTSKSVLAALYSSEGSVLERHHFSQTICVLNSEGCNIFENFSRQDYHHVLDLIRDIILATDLAHHLRIISDQRKMIDTFYDSNSNHHHVLLMDLLMTSADLSDQSKNWKNTRAVAQLIYEEFFSQGDMEKSIGQKPAEQMDRERACVPSLQMSFLDGIALPCFQLFADLYPLFGQKMIENITNNRKKWEKLNEDIKNGKISANIFQLFHRDISPMR 2913
            MPIACCCLMKRKLSESCLENTERELLLGLSNIVSYEEIPDAVKTTINRVFPNSNSVRLEWINTRENSTKSIRSNGWMNENKIIPQSSLIINRKDRLQEQYSDYFDSENSDNFGIIVPLISSEMKEFQAFLSFSCQEFNQNEKKLLQTFENQVKVMFQRLERLKNSKDSNLQQSNLQD KLDSSDFYIDSTILSLCADLHDRDPGILQVKIIRFLKQRIHMESAFILTISNNNLELVCQAQDEQIFDPEKRFRVTDSIFERIMKEKICAQLSDVNMFQDKLNELELLTNIKWNSFLCVPIINQSDGCVSALVCMINKIGSNQSFTAEDISITQHLFQYTAAVLTSSVAFQMERRLKIQTETMLQVAMNIFRKLGDLTGLLKEIMTEAKKLTNAERCSVFLVDNDTKELVSKVFDGLPTISEQSQHPVEIRIPVTQGVAGRVATTGEMLNIVDAYSHPLFYRGVDEETGYKTRNILCFPIKDENEKVVGVAQLCNKINGPCFTNYDEDIAKAFSVYCCISIMHSLMYKKVQDAQHRNKLANELMIYHMQVNEDTVKWLTSCGYPDLMDIKEDFNSFECIPRDIKEHDSALAVLGMFNTLGFISKWRLSRPTLSRFILMIKRGYRDPPYHNWTHAFSVAHFIYLCITNLPLHGQLLPIELLALFVASLCHDIDHRGTNNSFQVTSKSVLAALYSSEGSVLERHHFSQTICVLNSEGCNIFENFSRQDYHHVLDLIRDIILATDLAHHLRIISDQRKMIDTFYDSNSNHHHVLLMDLLMTSADLSDQSKNWKNTRAVAQLIYEEFFSQGDMEKSIGQKPAEQMDRERACVPSLQMSFLDGIALPCFQLFADLYPLFGQKMIENITNNRKKWEKLNEDIKNGKISANIFQLFHRDISPMR
Sbjct:    1 MPIACCCLMKRKLSESCLENTERELLLGLSNIVSYEEIPDAVKTTINRVFPNSNSVRLEWINTRENSTKSIRSNGWMNENKIIPQSSLIINRKDRLQEQYSDYFDSENSDNFGIIVPLISSEMKEFQAFLSFSCQEFNQNEKKLLQTFENQVKVMFQRLERLKNSKDSNLQQSNLQDPKLDSSDFYIDSTILSLCADLHDRDPGILQVKIIRFLKQRIHMESAFILTISNNNLELVCQAQDEQIFDPEKRFRVTDSIFERIMKEKICAQLSDVNMFQDKLNELELLTNIKWNSFLCVPIINQSDGCVSALVCMINKIGSNQSFTAEDISITQHLFQYTAAVLTSSVAFQMERRLKIQTETMLQVAMNIFRKLGDLTGLLKEIMTEAKKLTNAERCSVFLVDNDTKELVSKVFDGLPTISEQSQHPVEIRIPVTQGVAGRVATTGEMLNIVDAYSHPLFYRGVDEETGYKTRNILCFPIKDENEKVVGVAQLCNKINGPCFTNYDEDIAKAFSVYCCISIMHSLMYKKVQDAQHRNKLANELMIYHMQVNEDTVKWLTSCGYPDLMDIKEDFNSFECIPRDIKEHDSALAVLGMFNTLGFISKWRLSRPTLSRFILMIKRGYRDPPYHNWTHAFSVAHFIYLCITNLPLHGQLLPIELLALFVASLCHDIDHRGTNNSFQVTSKSVLAALYSSEGSVLERHHFSQTICVLNSEGCNIFENFSRQDYHHVLDLIRDIILATDLAHHLRIISDQRKMIDTFYDSNSNHHHVLLMDLLMTSADLSDQSKNWKNTRAVAQLIYEEFFSQGDMEKSIGQKPAEQMDRERACVPSLQMSFLDGIALPCFQLFADLYPLFGQKMIENITNNRKKWEKLNEDIKNGKISANIFQLFHRDISPMR 895

[Close]

BLAST of Phosphodiesterase vs. Planmine SMEST
Match: SMESG000051078.1 (SMESG000051078.1)

HSP 1 Score: 1841.63 bits (4769), Expect = 0.000e+0
Identity = 886/887 (99.89%), Postives = 886/887 (99.89%), Query Frame = 1

Query:  253 MKRKLSESCLENTERELLLGLSNIVSYEEIPDAVKTTINRVFPNSNSVRLEWINTRENSTKSIRSNGWMNENKIIPQSSLIINRKDRLQEQYSDYFDSENSDNFGIIVPLISSEMKEFQAFLSFSCQEFNQNEKKLLQTFENQVKVMFQRLERLKNSKDSNLQQSNLQDTKLDSSDFYIDSTILSLCADLHDRDPGILQVKIIRFLKQRIHMESAFILTISNNNLELVCQAQDEQIFDPEKRFRVTDSIFERIMKEKICAQLSDVNMFQDKLNELELLTNIKWNSFLCVPIINQSDGCVSALVCMINKIGSNQSFTAEDISITQHLFQYTAAVLTSSVAFQMERRLKIQTETMLQVAMNIFRKLGDLTGLLKEIMTEAKKLTNAERCSVFLVDNDTKELVSKVFDGLPTISEQSQHPVEIRIPVTQGVAGRVATTGEMLNIVDAYSHPLFYRGVDEETGYKTRNILCFPIKDENEKVVGVAQLCNKINGPCFTNYDEDIAKAFSVYCCISIMHSLMYKKVQDAQHRNKLANELMIYHMQVNEDTVKWLTSCGYPDLMDIKEDFNSFECIPRDIKEHDSALAVLGMFNTLGFISKWRLSRPTLSRFILMIKRGYRDPPYHNWTHAFSVAHFIYLCITNLPLHGQLLPIELLALFVASLCHDIDHRGTNNSFQVTSKSVLAALYSSEGSVLERHHFSQTICVLNSEGCNIFENFSRQDYHHVLDLIRDIILATDLAHHLRIISDQRKMIDTFYDSNSNHHHVLLMDLLMTSADLSDQSKNWKNTRAVAQLIYEEFFSQGDMEKSIGQKPAEQMDRERACVPSLQMSFLDGIALPCFQLFADLYPLFGQKMIENITNNRKKWEKLNEDIKNGKISANIFQLFHRDISPMR 2913
            MKRKLSESCLENTERELLLGLSNIVSYEEIPDAVKTTINRVFPNSNSVRLEWINTRENSTKSIRSNGWMNENKIIPQSSLIINRKDRLQEQYSDYFDSENSDNFGIIVPLISSEMKEFQAFLSFSCQEFNQNEKKLLQTFENQVKVMFQRLERLKNSKDSNLQQSNLQD KLDSSDFYIDSTILSLCADLHDRDPGILQVKIIRFLKQRIHMESAFILTISNNNLELVCQAQDEQIFDPEKRFRVTDSIFERIMKEKICAQLSDVNMFQDKLNELELLTNIKWNSFLCVPIINQSDGCVSALVCMINKIGSNQSFTAEDISITQHLFQYTAAVLTSSVAFQMERRLKIQTETMLQVAMNIFRKLGDLTGLLKEIMTEAKKLTNAERCSVFLVDNDTKELVSKVFDGLPTISEQSQHPVEIRIPVTQGVAGRVATTGEMLNIVDAYSHPLFYRGVDEETGYKTRNILCFPIKDENEKVVGVAQLCNKINGPCFTNYDEDIAKAFSVYCCISIMHSLMYKKVQDAQHRNKLANELMIYHMQVNEDTVKWLTSCGYPDLMDIKEDFNSFECIPRDIKEHDSALAVLGMFNTLGFISKWRLSRPTLSRFILMIKRGYRDPPYHNWTHAFSVAHFIYLCITNLPLHGQLLPIELLALFVASLCHDIDHRGTNNSFQVTSKSVLAALYSSEGSVLERHHFSQTICVLNSEGCNIFENFSRQDYHHVLDLIRDIILATDLAHHLRIISDQRKMIDTFYDSNSNHHHVLLMDLLMTSADLSDQSKNWKNTRAVAQLIYEEFFSQGDMEKSIGQKPAEQMDRERACVPSLQMSFLDGIALPCFQLFADLYPLFGQKMIENITNNRKKWEKLNEDIKNGKISANIFQLFHRDISPMR
Sbjct:    1 MKRKLSESCLENTERELLLGLSNIVSYEEIPDAVKTTINRVFPNSNSVRLEWINTRENSTKSIRSNGWMNENKIIPQSSLIINRKDRLQEQYSDYFDSENSDNFGIIVPLISSEMKEFQAFLSFSCQEFNQNEKKLLQTFENQVKVMFQRLERLKNSKDSNLQQSNLQDPKLDSSDFYIDSTILSLCADLHDRDPGILQVKIIRFLKQRIHMESAFILTISNNNLELVCQAQDEQIFDPEKRFRVTDSIFERIMKEKICAQLSDVNMFQDKLNELELLTNIKWNSFLCVPIINQSDGCVSALVCMINKIGSNQSFTAEDISITQHLFQYTAAVLTSSVAFQMERRLKIQTETMLQVAMNIFRKLGDLTGLLKEIMTEAKKLTNAERCSVFLVDNDTKELVSKVFDGLPTISEQSQHPVEIRIPVTQGVAGRVATTGEMLNIVDAYSHPLFYRGVDEETGYKTRNILCFPIKDENEKVVGVAQLCNKINGPCFTNYDEDIAKAFSVYCCISIMHSLMYKKVQDAQHRNKLANELMIYHMQVNEDTVKWLTSCGYPDLMDIKEDFNSFECIPRDIKEHDSALAVLGMFNTLGFISKWRLSRPTLSRFILMIKRGYRDPPYHNWTHAFSVAHFIYLCITNLPLHGQLLPIELLALFVASLCHDIDHRGTNNSFQVTSKSVLAALYSSEGSVLERHHFSQTICVLNSEGCNIFENFSRQDYHHVLDLIRDIILATDLAHHLRIISDQRKMIDTFYDSNSNHHHVLLMDLLMTSADLSDQSKNWKNTRAVAQLIYEEFFSQGDMEKSIGQKPAEQMDRERACVPSLQMSFLDGIALPCFQLFADLYPLFGQKMIENITNNRKKWEKLNEDIKNGKISANIFQLFHRDISPMR 887

[Close]

BLAST of Phosphodiesterase vs. Planmine SMEST
Match: SMESG000075722.1 (SMESG000075722.1)

HSP 1 Score: 1011.13 bits (2613), Expect = 0.000e+0
Identity = 510/916 (55.68%), Postives = 659/916 (71.94%), Query Frame = 1

Query:  229 MPIACCCLMKRKLSESCLENTERELLLGLSNIVSYEEIPDAVKTTINRVFPNSNSVRLEW-INTRENSTKSIRSNGWMNENKI-IP--QSSLIINRKDRLQEQYSDYFDSENSDNFGIIVPLISSEMKEFQAFLSFSCQEFNQNEKKLLQTFENQVKVMFQRLERLKNSKDSNLQQSNLQDTKLDSSDFYIDS--TILSLCADLHDRDPGILQVKIIRFLKQRIHMESAFILTISNNNLELVCQAQDEQIFDPEKRFRVTDSIFERIMKEKICAQLSDVNMFQDKLNELELL---TNIKWNSFLCVPIINQSDGCVSALVCMINKIGSNQSFTAEDISITQHLFQYTAAVLTSSVAFQMERRLKIQTETMLQVAMNIFRKLGDLTGLLKEIMTEAKKLTNAERCSVFLVDNDTKELVSKVFDGLPTISEQS-------------QHPVEIRIPVTQGVAGRVATTGEMLNIVDAYSHPLFYRGVDEETGYKTRNILCFPIKDENEKVVGVAQLCNKINGPCFTNYDEDIAKAFSVYCCISIMHSLMYKKVQDAQHRNKLANELMIYHMQVNEDTVKWLTSCGYPDLMDIKEDFNSFECIPRDIKEHDSALAVLGMFNTLGFISKWRLSRPTLSRFILMIKRGYRDPPYHNWTHAFSVAHFIYLCITNLPLHGQLLPIELLALFVASLCHDIDHRGTNNSFQVTSKSVLAALYSSEGSVLERHHFSQTICVLNSEGCNIFENFSRQDYHHVLDLIRDIILATDLAHHLRIISDQRKMIDTFYDSNSNHHHVLLMDLLMTSADLSDQSKNWKNTRAVAQLIYEEFFSQGDMEKSIGQKPAEQMDRERACVPSLQMSFLDGIALPCFQLFADLYPLFGQKMIENITNNRKKWEKLNEDIKNGKISANIFQLFHRDISPM 2910
            M I CCC + +    +  E+ E+  +  L  I+S  E+ + V   I+++F  S  +++ W   +  N      S+ W    KI +P  +  LI+  K   +  Y++ F      N+GI +P+   E   F A+L+F C +++    K L   E Q+K+MFQRL  +  S         L    + S++   ++   IL+LC +L DRDP +LQ+KII FLK  IH+++ FIL +S    E  CQ  D  I +PE R  + +SI E I+KE  C +    +  Q+KL +L++L   T  KW+S L +PI++  +  + A+V +++KI S +SF ++DI + Q +F++T  VL SS+A+ +E++ K+QTE MLQVAMNIFRKL +LT LLKEIMTEAKKLTNAERCSVFL++ +T ELVSKVFDGLPT+SE S             + P EIRI  +QG+AG+VATTGE+LNI+DAYSHPLFYRGVDE TGY+TRNILCFPIKDE +K+VGVAQLCNK+NGP FT+ DED+AKAFSVYCCISI+HSLMYK VQ+AQHRNKLANELM YHMQ++E+   WL++C  P++     DFNSF+ IPR + EH+S LA L MF+TL FIS+WR+ R  L+RFILM+KRGYRDPPYHNWTHA SVAHF YLC  NL L  QL  +E+ + FVA LCHDIDHRGTNNSFQVTS SVLAALYSSEGSVLERHHF+QTIC+LNSEG N+FEN +RQ+Y   LDLIRDIILATDLAHH RII+ QR+MI++ YD ++  H  LL+ LLMT ADLSDQ K+W+N R VA+LIYEEFF+QGD+EK+IGQKPAEQMDRERAC+PSLQ+SFLDG+A+PCFQ FA LY   G+ M++ +  NRKKWEKLN DI++GKI+ANIFQLF +D+SP+
Sbjct:    1 MAITCCCGINKLSHSNHNEDVEQISIHELVTIISPAEVEETVTRVISKLFQKSEKIKILWEFKSVSNHLNHTHSSIW----KINLPDHKGKLILTSKQMDKSVYANLFKERAGSNYGIFLPIFDDENSMFNAYLTFYCNQWDSKSTKTLDHLEKQIKIMFQRLTVMNGS---------LMSPSISSAEISNETRNAILTLCGELFDRDPCVLQMKIINFLKGMIHVKTGFILIVSTEISEFGCQVIDSTIVNPELRCEIRNSIIESIVKEN-CVKKVKSSEIQNKLGDLKVLQSLTGFKWDSLLLIPILSSLNNSLVAIVGLVDKINS-ESFNSKDIELIQLVFRFTNPVLISSLAYYVEKKTKVQTEAMLQVAMNIFRKLDNLTMLLKEIMTEAKKLTNAERCSVFLLEEETNELVSKVFDGLPTVSENSPTSVFITPEGEEYEQPKEIRISTSQGIAGKVATTGEILNILDAYSHPLFYRGVDESTGYRTRNILCFPIKDEKDKIVGVAQLCNKVNGPHFTSSDEDLAKAFSVYCCISIVHSLMYKNVQEAQHRNKLANELMTYHMQISEENFLWLSTCPIPEVSVFLPDFNSFDSIPRQMNEHNSVLATLSMFHTLKFISRWRIPRSVLARFILMVKRGYRDPPYHNWTHALSVAHFAYLCGKNLDLMNQLNELEIFSFFVAGLCHDIDHRGTNNSFQVTSNSVLAALYSSEGSVLERHHFNQTICILNSEGSNLFENLNRQEYQKALDLIRDIILATDLAHHFRIINQQREMIESGYDKSNPDHRKLLLFLLMTCADLSDQIKSWENARNVARLIYEEFFTQGDLEKAIGQKPAEQMDRERACIPSLQISFLDGVAIPCFQNFAKLYRQPGESMLKIMQENRKKWEKLNNDIRDGKITANIFQLFQKDMSPL 901

[Close]

BLAST of Phosphodiesterase vs. Planmine SMEST
Match: SMESG000021196.1 (SMESG000021196.1)

HSP 1 Score: 825.469 bits (2131), Expect = 0.000e+0
Identity = 433/868 (49.88%), Postives = 585/868 (67.40%), Query Frame = 1

Query:  304 LLGLSNIVSYEEIPDAVKTTINRVFPNSNSVRLEWINTRENSTKSIRSNGWMNENKIIPQSSLIINRKDRLQEQYSDYFDSENSDNFGIIVPLISSEMKEFQAFLSFSCQEFNQNEK---KLLQTFENQVKVMFQRLERLKNSKDSNLQQSNLQDTKLDSSDFYIDSTILSLCADLHDRDPGILQVKIIRFLKQRIHMESAFILTISNNNLELVCQA-----QDEQI-FDPEKRFRVTDSIFERIMKEKICAQLSDVNMFQDKLNELELLTN-----IKWNSFLCVPIINQSDGCVSALVCMINKIGSNQSFTAEDISITQHLFQYTAAVLTSSVAFQMERRLKIQTETMLQVAMNIFRKLGDLTGLLKEIMTEAKKLTNAERCSVFLVDNDTKELVSKVFDGLPTISEQSQHPVEIRIPVTQGVAGRVATTGEMLNIVDAYSHPLFYRGVDEETGYKTRNILCFPIKDENEKVVGVAQLCNKINGPCFTNYDEDIAKAFSVYCCISIMHSLMYKKVQDAQHRNKLANELMIYHMQVNEDTVKWLTSCGYPDLMDIKEDFNSFECIPRDIKEHDSALAVLGMFNTLGFISKWRLSRPTLSRFILMIKRGYRDPPYHNWTHAFSVAHFIYLCITNLPLHGQLLPIELLALFVASLCHDIDHRGTNNSFQVTSKSVLAALYSSEGSVLERHHFSQTICVLNSEGCNIFENFSRQDYHHVLDLIRDIILATDLAHHLRIISDQRKMIDTFYDSNSNHHHVLLMDLLMTSADLSDQSKNWKNTRAVAQLIYEEFFSQGDMEKSIGQKPAEQMDRERACVPSLQMSFLDGIALPCFQLFADLYPLFGQKMIENITNNRKKWEKLNEDIKNGKI 2865
            LLG+  ++SY+E     K  +  +FP + +V++  ++  E     IR+   +     +  S L    +D  +   S   D   S+++ I+V +  S  +  ++ L    Q+FN+N +   K L   E Q+ +   RL R+  +K  + Q +                 IL LC  L D+D G LQ K++ +L Q    E+ F+L +  + +EL+CQ      Q++ I FD E+     + IF++++K K    L  +   + +L E+  + N      K  + LCVP+ +Q    V A+VC+INK G  Q FT  D  +    F+YT +VL +++A+Q ERRLK+QTE ML VA NIF ++ +L  LL  IM EA+ LT AERCSVFLVD D+ ELV+KVFDGLPT S++++ PVEIR P  QG+AG VATTGEMLNI  AY HPLFYRGVD+ETG+KT+NILCFPI+D+  K VGVAQLCNKI G  FT  DE+IAKAFS+YCCISI HSLMYKKV+DAQHR++LANELM+YHMQ+ ED + WL++   P +     DF SF  IPR++K+ D+ +A + MF+ +G IS+WR++R TL++FI M+KR YRDPPYHNW HAFSVAHFI++CI NLPL  QL  +EL ALFVASLCHDIDHRGTNNSFQV S S+LAALYSSEGSVLERHHFSQT+C+LN+EGCN+FE+  +++Y   LDLIRDIILATDLAHHL+I S   KM    YD+  + +H LL+ LLMTSADLSDQ+KNW+NTR+VA+LIY+EFF QGD+EK+IG +PAEQMDRERA VP+LQ++FLDGI  P +++ + L+P     +   I   R+ W K+++ + + +I
Sbjct:   27 LLGV--VISYDEFLSKSKYAVKILFPLATAVQMHQVS--EIKHPKIRAMCTIRRTSFLYVSDL----EDLSEIISSGELDILKSNSYDILVIVSVSSSQPKESLLLTFFQKFNENSENRSKRLDFLEKQMSLTLSRLMRIHPNKIISNQINQ----------------ILELCGSLFDQDAGKLQKKVLSYLIQNTSAETGFLLLVCMDTVELLCQVIGQVIQEDPINFDAEE-----NGIFDKVLKSKTGINLGCLT--EAQLREISEIMNASKQETKIQNALCVPVRHQGTNDVIAIVCLINKSGPAQ-FTNYDEQVINECFKYTTSVLFTTIAYQNERRLKLQTEKMLVVAKNIFSRMDNLNELLLMIMQEARNLTQAERCSVFLVDEDSNELVAKVFDGLPTSSDKNEQPVEIRFPKAQGIAGHVATTGEMLNIKKAYDHPLFYRGVDDETGFKTKNILCFPIQDDCGKTVGVAQLCNKIKGHFFTKMDEEIAKAFSIYCCISITHSLMYKKVEDAQHRSRLANELMMYHMQIPEDDIAWLSTFSIPPVSIFLSDFESFNSIPRNVKDRDTLMACISMFDGIGLISRWRINRRTLTKFIFMVKRNYRDPPYHNWMHAFSVAHFIFICIKNLPLDKQLTELELFALFVASLCHDIDHRGTNNSFQVQSNSILAALYSSEGSVLERHHFSQTVCILNTEGCNVFESLPQKEYIKALDLIRDIILATDLAHHLQIFSKIEKMAQQGYDNLDSENHNLLLCLLMTSADLSDQTKNWRNTRSVAELIYKEFFRQGDLEKAIGNQPAEQMDRERAVVPNLQIAFLDGIVSPLYRVLSLLHPQ-TDCINHTIERTRENWSKISQKVASHEI 861

[Close]

BLAST of Phosphodiesterase vs. Planmine SMEST
Match: SMESG000021196.1 (SMESG000021196.1)

HSP 1 Score: 817.765 bits (2111), Expect = 0.000e+0
Identity = 434/879 (49.37%), Postives = 585/879 (66.55%), Query Frame = 1

Query:  304 LLGLSNIVSYEEIPDAVKTTINRVFPNSNSVRLEWINTRENSTKSIRSNGWMNENKIIPQSSLIINRKDRLQEQYSDYFDSENSDNFGIIVPLISSEMKEFQAFLSFSCQEFNQNEK---KLLQTFENQVKVMFQRLERLKNSKDSNLQQSNLQDTKLDSSDFYIDSTILSLCADLHDRDPGILQVKIIRFLKQRIHMESAFILTISNNNLELVCQA-----QDEQI-FDPEKRFRVTDSIFERIMKEKICAQLSDVNMFQDKLNELELLTN-----IKWNSFLCVPIINQSDGCVSALVCMINKIGSNQSFTAEDISITQHLFQYTAAVLTSSVAFQMERRLKIQTETMLQVAMNIFRKLGDLTGLLKEIMTEAKKLTNAERCSVFLVDNDTKELVSKVFDGLPTISEQS-----------QHPVEIRIPVTQGVAGRVATTGEMLNIVDAYSHPLFYRGVDEETGYKTRNILCFPIKDENEKVVGVAQLCNKINGPCFTNYDEDIAKAFSVYCCISIMHSLMYKKVQDAQHRNKLANELMIYHMQVNEDTVKWLTSCGYPDLMDIKEDFNSFECIPRDIKEHDSALAVLGMFNTLGFISKWRLSRPTLSRFILMIKRGYRDPPYHNWTHAFSVAHFIYLCITNLPLHGQLLPIELLALFVASLCHDIDHRGTNNSFQVTSKSVLAALYSSEGSVLERHHFSQTICVLNSEGCNIFENFSRQDYHHVLDLIRDIILATDLAHHLRIISDQRKMIDTFYDSNSNHHHVLLMDLLMTSADLSDQSKNWKNTRAVAQLIYEEFFSQGDMEKSIGQKPAEQMDRERACVPSLQMSFLDGIALPCFQLFADLYPLFGQKMIENITNNRKKWEKLNEDIKNGKI 2865
            LLG+  ++SY+E     K  +  +FP + +V++  ++  E     IR+   +     +  S L    +D  +   S   D   S+++ I+V +  S  +  ++ L    Q+FN+N +   K L   E Q+ +   RL R+  +K  + Q +                 IL LC  L D+D G LQ K++ +L Q    E+ F+L +  + +EL+CQ      Q++ I FD E+     + IF++++K K    L  +   + +L E+  + N      K  + LCVP+ +Q    V A+VC+INK G  Q FT  D  +    F+YT +VL +++A+Q ERRLK+QTE ML VA NIF ++ +L  LL  IM EA+ LT AERCSVFLVD D+ ELV+KVFDGLPT S+++           Q PVEIR P  QG+AG VATTGEMLNI  AY HPLFYRGVD+ETG+KT+NILCFPI+D+  K VGVAQLCNKI G  FT  DE+IAKAFS+YCCISI HSLMYKKV+DAQHR++LANELM+YHMQ+ ED + WL++   P +     DF SF  IPR++K+ D+ +A + MF+ +G IS+WR++R TL++FI M+KR YRDPPYHNW HAFSVAHFI++CI NLPL  QL  +EL ALFVASLCHDIDHRGTNNSFQV S S+LAALYSSEGSVLERHHFSQT+C+LN+EGCN+FE+  +++Y   LDLIRDIILATDLAHHL+I S   KM    YD+  + +H LL+ LLMTSADLSDQ+KNW+NTR+VA+LIY+EFF QGD+EK+IG +PAEQMDRERA VP+LQ++FLDGI  P +++ + L+P     +   I   R+ W K+++ + + +I
Sbjct:   27 LLGV--VISYDEFLSKSKYAVKILFPLATAVQMHQVS--EIKHPKIRAMCTIRRTSFLYVSDL----EDLSEIISSGELDILKSNSYDILVIVSVSSSQPKESLLLTFFQKFNENSENRSKRLDFLEKQMSLTLSRLMRIHPNKIISNQINQ----------------ILELCGSLFDQDAGKLQKKVLSYLIQNTSAETGFLLLVCMDTVELLCQVIGQVIQEDPINFDAEE-----NGIFDKVLKSKTGINLGCLT--EAQLREISEIMNASKQETKIQNALCVPVRHQGTNDVIAIVCLINKSGPAQ-FTNYDEQVINECFKYTTSVLFTTIAYQNERRLKLQTEKMLVVAKNIFSRMDNLNELLLMIMQEARNLTQAERCSVFLVDEDSNELVAKVFDGLPTSSDKNERLRLQDGTEIQQPVEIRFPKAQGIAGHVATTGEMLNIKKAYDHPLFYRGVDDETGFKTKNILCFPIQDDCGKTVGVAQLCNKIKGHFFTKMDEEIAKAFSIYCCISITHSLMYKKVEDAQHRSRLANELMMYHMQIPEDDIAWLSTFSIPPVSIFLSDFESFNSIPRNVKDRDTLMACISMFDGIGLISRWRINRRTLTKFIFMVKRNYRDPPYHNWMHAFSVAHFIFICIKNLPLDKQLTELELFALFVASLCHDIDHRGTNNSFQVQSNSILAALYSSEGSVLERHHFSQTVCILNTEGCNVFESLPQKEYIKALDLIRDIILATDLAHHLQIFSKIEKMAQQGYDNLDSENHNLLLCLLMTSADLSDQTKNWRNTRSVAELIYKEFFRQGDLEKAIGNQPAEQMDRERAVVPNLQIAFLDGIVSPLYRVLSLLHPQ-TDCINHTIERTRENWSKISQKVASHEI 872

The following BLAST results are available for this feature:

BLAST of Phosphodiesterase vs. Ensembl Human
BLAST of Phosphodiesterase vs. Ensembl Celegans
BLAST of Phosphodiesterase vs. Ensembl Fly
BLAST of Phosphodiesterase vs. Ensembl Zebrafish
BLAST of Phosphodiesterase vs. Ensembl Xenopus
BLAST of Phosphodiesterase vs. Ensembl Mouse
BLAST of Phosphodiesterase vs. UniProt/SwissProt
BLAST of Phosphodiesterase vs. TrEMBL
BLAST of Phosphodiesterase vs. Ensembl Cavefish
BLAST of Phosphodiesterase vs. Ensembl Sea Lamprey
BLAST of Phosphodiesterase vs. Ensembl Yeast
BLAST of Phosphodiesterase vs. Ensembl Nematostella
BLAST of Phosphodiesterase vs. Ensembl Medaka
BLAST of Phosphodiesterase vs. Planmine SMEST

BLAST of Phosphodiesterase vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
PDE2A	0.000e+0	45.72	phosphodiesterase 2A [Source:HGNC Symbol;Acc:HGNC:...	[more]
PDE2A	0.000e+0	45.72	phosphodiesterase 2A [Source:HGNC Symbol;Acc:HGNC:...	[more]
PDE2A	0.000e+0	45.88	phosphodiesterase 2A [Source:HGNC Symbol;Acc:HGNC:...	[more]
PDE2A	0.000e+0	45.72	phosphodiesterase 2A [Source:HGNC Symbol;Acc:HGNC:...	[more]
PDE2A	0.000e+0	49.80	phosphodiesterase 2A [Source:HGNC Symbol;Acc:HGNC:...	[more]

BLAST of Phosphodiesterase vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5


Match Name	E-value	Identity	Description
pde-2	6.672e-109	38.49	Probable 3',5'-cyclic phosphodiesterase pde-2 [So...	[more]
pde-2	7.190e-109	38.49	Probable 3',5'-cyclic phosphodiesterase pde-2 [So...	[more]
pde-5	3.049e-105	37.57	Probable 3',5'-cyclic phosphodiesterase pde-5 [So...	[more]
pde-4	5.051e-33	26.53	Probable 3',5'-cyclic phosphodiesterase pde-4 [So...	[more]
pde-4	2.400e-32	26.53	Probable 3',5'-cyclic phosphodiesterase pde-4 [So...	[more]

BLAST of Phosphodiesterase vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Pde6	3.103e-96	32.09	gene:FBgn0038237 transcript:FBtr0300330	[more]
Pde6	3.103e-96	32.09	gene:FBgn0038237 transcript:FBtr0345168	[more]
Pde6	3.477e-96	32.09	gene:FBgn0038237 transcript:FBtr0330048	[more]
Pde11	4.200e-91	33.44	gene:FBgn0085370 transcript:FBtr0303163	[more]
Pde11	1.179e-90	33.44	gene:FBgn0085370 transcript:FBtr0303162	[more]

BLAST of Phosphodiesterase vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
pde11a	1.028e-101	32.89	phosphodiesterase 11a [Source:ZFIN;Acc:ZDB-GENE-07...	[more]
pde10a	2.304e-100	35.93	phosphodiesterase 10A [Source:ZFIN;Acc:ZDB-GENE-04...	[more]
pde10a	4.976e-100	36.51	phosphodiesterase 10A [Source:ZFIN;Acc:ZDB-GENE-04...	[more]
pde10a	7.347e-100	35.93	phosphodiesterase 10A [Source:ZFIN;Acc:ZDB-GENE-04...	[more]
pde11a	3.809e-96	32.62	phosphodiesterase 11a [Source:ZFIN;Acc:ZDB-GENE-07...	[more]

BLAST of Phosphodiesterase vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5


Match Name	E-value	Identity	Description
pde2a	4.374e-108	35.99	phosphodiesterase 2A [Source:NCBI gene;Acc:780063]	[more]
pde2a	1.316e-103	35.83	phosphodiesterase 2A [Source:NCBI gene;Acc:780063]	[more]
ENSXETT00000053056.1	1.871e-102	32.59	phosphodiesterase 11A [Source:NCBI gene;Acc:100379...	[more]
PDE10A	7.116e-96	36.78	phosphodiesterase 10A [Source:NCBI gene;Acc:100485...	[more]
PDE10A	1.481e-89	37.95	phosphodiesterase 10A [Source:NCBI gene;Acc:100485...	[more]

BLAST of Phosphodiesterase vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Pde2a	0.000e+0	45.54	phosphodiesterase 2A, cGMP-stimulated [Source:MGI ...	[more]
Gm45837	0.000e+0	45.74	predicted gene 45837 [Source:MGI Symbol;Acc:MGI:58...	[more]
Pde2a	0.000e+0	45.58	phosphodiesterase 2A, cGMP-stimulated [Source:MGI ...	[more]
Pde2a	0.000e+0	45.58	phosphodiesterase 2A, cGMP-stimulated [Source:MGI ...	[more]
Pde2a	0.000e+0	45.58	phosphodiesterase 2A, cGMP-stimulated [Source:MGI ...	[more]

BLAST of Phosphodiesterase vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|Q01062\|PDE2A_RAT	0.000e+0	45.82	cGMP-dependent 3',5'-cyclic phosphodiesterase OS=R...	[more]
sp\|Q922S4\|PDE2A_MOUSE	0.000e+0	45.54	cGMP-dependent 3',5'-cyclic phosphodiesterase OS=M...	[more]
sp\|P14099\|PDE2A_BOVIN	0.000e+0	45.14	cGMP-dependent 3',5'-cyclic phosphodiesterase OS=B...	[more]
sp\|O00408\|PDE2A_HUMAN	0.000e+0	45.72	cGMP-dependent 3',5'-cyclic phosphodiesterase OS=H...	[more]
sp\|P30645\|PDE2_CAEEL	8.486e-108	38.49	Probable 3',5'-cyclic phosphodiesterase pde-2 OS=C...	[more]

BLAST of Phosphodiesterase vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
A0A4Z2CV85	0.000e+0	49.82	Phosphodiesterase OS=Schistosoma japonicum OX=6182...	[more]
A0A0G2K876	0.000e+0	45.98	Phosphodiesterase OS=Rattus norvegicus OX=10116 GN...	[more]
F8WFW5	0.000e+0	45.82	Phosphodiesterase OS=Rattus norvegicus OX=10116 GN...	[more]
F7D3W5	0.000e+0	45.74	Phosphodiesterase OS=Mus musculus OX=10090 GN=Gm45...	[more]
Q5PR72	0.000e+0	45.58	Phosphodiesterase OS=Mus musculus OX=10090 GN=Pde2...	[more]

BLAST of Phosphodiesterase vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
pde11a	6.836e-103	32.95	phosphodiesterase 11a [Source:ZFIN;Acc:ZDB-GENE-07...	[more]
pde10a	4.362e-101	36.45	phosphodiesterase 10A [Source:ZFIN;Acc:ZDB-GENE-04...	[more]
pde11al	2.946e-95	31.72	dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 1...	[more]
pde11al	6.926e-90	31.25	dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 1...	[more]
pde11a	3.804e-89	31.19	phosphodiesterase 11a [Source:ZFIN;Acc:ZDB-GENE-07...	[more]

BLAST of Phosphodiesterase vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5


Match Name	E-value	Identity	Description
PDE2A	0.000e+0	55.52	phosphodiesterase 2A [Source:HGNC Symbol;Acc:HGNC:...	[more]
PDE2A	1.098e-167	60.21	phosphodiesterase 2A [Source:HGNC Symbol;Acc:HGNC:...	[more]
pde5ab	2.546e-76	29.44	phosphodiesterase 5A, cGMP-specific, b [Source:ZFI...	[more]
pde10a	3.502e-37	32.62	phosphodiesterase 10A [Source:ZFIN;Acc:ZDB-GENE-04...	[more]
PDE1C	1.101e-31	30.48	phosphodiesterase 1C [Source:HGNC Symbol;Acc:HGNC:...	[more]

BLAST of Phosphodiesterase vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 1


Match Name	E-value	Identity	Description
PDE2	9.368e-6	27.84	High-affinity cyclic AMP phosphodiesterase; compon...	[more]

BLAST of Phosphodiesterase vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5


Match Name	E-value	Identity	Description
EDO38644	1.579e-166	50.94	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO44626	1.315e-107	36.71	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO39522	2.150e-102	33.76	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO32088	3.526e-98	35.80	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO43657	5.395e-84	30.23	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of Phosphodiesterase vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5


Match Name	E-value	Identity	Description
pde11a	6.863e-101	32.32	phosphodiesterase 11A [Source:NCBI gene;Acc:101163...	[more]
pde10a	2.423e-100	35.51	phosphodiesterase 10A [Source:NCBI gene;Acc:101162...	[more]
pde10a	2.702e-100	35.51	phosphodiesterase 10A [Source:NCBI gene;Acc:101162...	[more]
pde10a	3.950e-100	35.51	phosphodiesterase 10A [Source:NCBI gene;Acc:101162...	[more]
pde5ab	1.319e-80	30.52	phosphodiesterase 5A [Source:NCBI gene;Acc:1011732...	[more]

BLAST of Phosphodiesterase vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5


Match Name	E-value	Identity	Description
SMESG000051078.1	0.000e+0	99.89	SMESG000051078.1	[more]
SMESG000051078.1	0.000e+0	99.89	SMESG000051078.1	[more]
SMESG000075722.1	0.000e+0	55.68	SMESG000075722.1	[more]
SMESG000021196.1	0.000e+0	49.88	SMESG000021196.1	[more]
SMESG000021196.1	0.000e+0	49.37	SMESG000021196.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30028097 ID=SMED30028097|Name=Phosphodiesterase|organism=Schmidtea mediterranea sexual|type=transcript|length=3069bp
CACTACTTTTCTTATCATTGTTAAGAAGAAGTTATTGTCTCTACAACTTT
TCAAGAAATTAAAAACGCAATATCTGGACAAAATTGGATCTCAACGAAAT
CTCAACGAATTATTGATTTGTGTATCTATTTTAAAGTGATTTATAAATAT
TATTGTACTTTCCTCAACGACTATTGGTCGATCGATTTGTCTGTGTAAAA
CTATTATGGCAAGTTACATTTTTCTACAATGCCAATCGCTTGTTGTTGCC
TTATGAAAAGAAAGCTGTCAGAATCATGTTTGGAAAATACTGAAAGGGAA
TTGCTTTTGGGATTGAGCAATATAGTTTCCTACGAAGAAATACCTGATGC
AGTGAAAACAACAATTAACCGAGTATTTCCCAACAGTAATTCTGTTCGAC
TAGAATGGATTAATACAAGAGAGAATAGCACCAAATCAATTAGATCCAAC
GGCTGGATGAATGAGAATAAAATAATTCCACAAAGCTCACTGATAATCAA
CCGAAAGGATAGATTACAAGAACAATACTCAGACTATTTTGATTCAGAAA
ATTCCGACAATTTTGGAATTATTGTTCCCTTAATTAGTTCAGAAATGAAG
GAATTTCAAGCTTTTTTATCATTTTCCTGCCAAGAGTTTAATCAGAATGA
AAAGAAACTTTTACAGACCTTTGAAAATCAGGTTAAAGTCATGTTTCAAA
GACTTGAACGTCTTAAAAATTCTAAAGATTCAAATCTTCAACAGTCAAAT
CTTCAAGACACCAAATTGGACAGTTCAGATTTTTACATAGATTCAACAAT
TCTTTCTTTATGCGCTGACTTACACGACCGAGATCCTGGAATTCTTCAAG
TGAAAATAATCAGATTTTTAAAACAAAGAATTCATATGGAATCAGCCTTT
ATTCTCACAATTTCCAACAATAATCTCGAATTAGTTTGTCAAGCACAAGA
TGAGCAAATATTTGATCCGGAAAAAAGATTTCGGGTAACAGATTCGATTT
TTGAAAGAATTATGAAAGAGAAAATCTGTGCTCAACTTTCTGATGTAAAT
ATGTTTCAAGACAAACTGAATGAGTTGGAACTACTCACAAATATCAAATG
GAATTCATTTTTGTGTGTACCTATTATCAACCAATCAGATGGATGCGTTA
GTGCGCTTGTGTGCATGATCAACAAAATTGGATCCAATCAAAGCTTCACT
GCCGAAGATATTTCAATTACCCAGCATTTATTTCAATATACAGCGGCGGT
CCTAACGAGCAGTGTGGCATTTCAAATGGAACGGAGACTGAAAATCCAGA
CAGAGACCATGCTACAGGTTGCAATGAACATTTTTCGTAAGCTTGGCGAC
CTAACCGGTTTGTTAAAAGAAATTATGACAGAAGCAAAAAAGCTTACTAA
TGCCGAAAGATGTTCTGTATTCTTGGTTGACAATGACACAAAAGAACTTG
TATCAAAAGTGTTTGATGGATTACCAACGATTTCCGAACAAAGTCAACAT
CCGGTTGAAATTAGAATCCCAGTAACTCAAGGAGTAGCAGGCAGAGTAGC
AACGACTGGGGAAATGCTGAATATTGTTGATGCCTATAGTCATCCGTTAT
TTTATCGTGGTGTTGATGAAGAAACCGGTTACAAAACAAGAAATATATTA
TGCTTCCCAATCAAAGACGAAAACGAAAAGGTTGTGGGCGTTGCTCAGTT
ATGCAATAAGATTAATGGGCCATGTTTCACAAATTATGATGAAGATATTG
CAAAGGCATTTTCAGTTTATTGTTGCATAAGCATCATGCATTCACTGATG
TATAAGAAAGTGCAAGATGCTCAACACCGGAACAAATTGGCTAATGAATT
GATGATATATCACATGCAAGTGAATGAGGACACAGTCAAGTGGTTAACAA
GTTGTGGTTATCCAGATCTCATGGATATAAAAGAAGATTTCAACAGCTTT
GAATGTATTCCGAGGGATATCAAAGAACATGATTCAGCTTTAGCAGTTCT
GGGGATGTTTAATACTTTGGGATTCATCAGCAAATGGCGATTATCGCGAC
CAACGTTATCAAGGTTCATATTAATGATCAAAAGAGGATATCGGGATCCA
CCTTATCACAACTGGACTCATGCTTTTTCAGTTGCTCATTTTATTTATTT
ATGCATTACAAATCTGCCTCTTCATGGACAATTGCTACCCATTGAGTTAT
TAGCATTATTTGTCGCTTCCTTGTGTCATGACATTGATCACAGAGGAACT
AATAATTCTTTTCAAGTTACATCAAAATCAGTTCTAGCTGCACTTTATAG
CAGTGAAGGTTCAGTTTTAGAGCGGCATCATTTTTCACAGACAATATGCG
TTTTGAATAGTGAAGGATGTAATATATTTGAAAACTTTTCAAGACAAGAT
TATCATCATGTTTTGGATTTGATTAGAGATATCATATTGGCCACAGATCT
CGCGCACCATTTGCGAATAATTTCTGACCAGAGAAAAATGATTGATACCT
TTTATGATTCAAATTCGAATCACCATCATGTTCTTCTAATGGATTTATTG
ATGACAAGTGCTGATCTCAGTGATCAATCGAAAAATTGGAAAAATACTCG
CGCCGTTGCACAATTGATTTATGAAGAGTTTTTCAGTCAAGGCGATATGG
AGAAGTCCATTGGTCAAAAGCCCGCAGAACAGATGGACAGAGAAAGAGCA
TGTGTTCCTAGTCTACAGATGTCATTTCTAGATGGAATAGCTTTGCCATG
TTTTCAGTTATTTGCCGACCTTTATCCATTATTCGGTCAAAAAATGATAG
AAAATATTACAAATAATCGAAAGAAATGGGAAAAATTGAACGAAGACATA
AAAAATGGAAAGATATCGGCAAATATCTTCCAGTTATTCCATAGAGATAT
TTCCCCGATGCGTAGTTTATCTTCTGTTGACGATTCATAGAGTTGATTTT
GTCCGCTTGAGTTGTATCCAGTATTTGATAAAAATGTAGAACAATCAAAC
AAGAAAAAAAAATCAAGCAAAATTACGTATATTTTTGATTTTTACAATAT
ATTTTGTTTAAATAGATCG

protein sequence of SMED30028097-orf-1

>SMED30028097-orf-1 ID=SMED30028097-orf-1|Name=SMED30028097-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=904bp
MPIACCCLMKRKLSESCLENTERELLLGLSNIVSYEEIPDAVKTTINRVF
PNSNSVRLEWINTRENSTKSIRSNGWMNENKIIPQSSLIINRKDRLQEQY
SDYFDSENSDNFGIIVPLISSEMKEFQAFLSFSCQEFNQNEKKLLQTFEN
QVKVMFQRLERLKNSKDSNLQQSNLQDTKLDSSDFYIDSTILSLCADLHD
RDPGILQVKIIRFLKQRIHMESAFILTISNNNLELVCQAQDEQIFDPEKR
FRVTDSIFERIMKEKICAQLSDVNMFQDKLNELELLTNIKWNSFLCVPII
NQSDGCVSALVCMINKIGSNQSFTAEDISITQHLFQYTAAVLTSSVAFQM
ERRLKIQTETMLQVAMNIFRKLGDLTGLLKEIMTEAKKLTNAERCSVFLV
DNDTKELVSKVFDGLPTISEQSQHPVEIRIPVTQGVAGRVATTGEMLNIV
DAYSHPLFYRGVDEETGYKTRNILCFPIKDENEKVVGVAQLCNKINGPCF
TNYDEDIAKAFSVYCCISIMHSLMYKKVQDAQHRNKLANELMIYHMQVNE
DTVKWLTSCGYPDLMDIKEDFNSFECIPRDIKEHDSALAVLGMFNTLGFI
SKWRLSRPTLSRFILMIKRGYRDPPYHNWTHAFSVAHFIYLCITNLPLHG
QLLPIELLALFVASLCHDIDHRGTNNSFQVTSKSVLAALYSSEGSVLERH
HFSQTICVLNSEGCNIFENFSRQDYHHVLDLIRDIILATDLAHHLRIISD
QRKMIDTFYDSNSNHHHVLLMDLLMTSADLSDQSKNWKNTRAVAQLIYEE
FFSQGDMEKSIGQKPAEQMDRERACVPSLQMSFLDGIALPCFQLFADLYP
LFGQKMIENITNNRKKWEKLNEDIKNGKISANIFQLFHRDISPMRSLSSV
DDS*

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000034	epidermis
PLANA:0000099	neuron
PLANA:0000101	muscle cell

Vocabulary: **INTERPRO**
Term	Definition
IPR036971	PDEase_catalytic_dom_sf
IPR023088	PDEase
IPR003018	GAF
IPR003607	HD/PDEase_dom
IPR002073	PDEase_catalytic_dom
IPR029016	GAF-like_dom_sf
IPR023174	PDEase_CS
IPR021109	Peptidase_aspartic_dom_sf

Vocabulary: **molecular function**
Term	Definition
GO:0008081	phosphoric diester hydrolase activity
GO:0005515	protein binding
GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity
GO:0016787	hydrolase activity
GO:0046872	metal ion binding

Vocabulary: **biological process**
Term	Definition
GO:0007165	signal transduction

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
None	No IPR available	COILS	Coil	Coil	coord: 857..877
None	No IPR available	COILS	Coil	Coil	coord: 145..165
None	No IPR available	PANTHER	PTHR11347:SF102	PHOSPHODIESTERASE	coord: 333..880
None	No IPR available	PANTHER	PTHR11347	CYCLIC NUCLEOTIDE PHOSPHODIESTERASE	coord: 333..880
None	No IPR available	SUPERFAMILY	SSF55781	GAF domain-like	coord: 189..369
None	No IPR available	SUPERFAMILY	SSF109604	HD-domain/PDEase-like	coord: 562..878
None	No IPR available	SUPERFAMILY	SSF55781	GAF domain-like	coord: 359..546
IPR023088	3'5'-cyclic nucleotide phosphodiesterase	PRINTS	PR00387	PDIESTERASE1	coord: 622..635 score: 55.0 coord: 667..682 score: 58.5 coord: 775..788 score: 44.86 coord: 792..808 score: 51.53 coord: 653..666 score: 33.71 coord: 695..711 score: 45.41
IPR003018	GAF domain	SMART	SM00065	gaf_1	coord: 202..352 e-value: 2.0E-5 score: 34.0 coord: 374..529 e-value: 7.2E-32 score: 121.9
IPR003018	GAF domain	PFAM	PF01590	GAF	coord: 374..513 e-value: 1.3E-15 score: 58.2
IPR003607	HD/PDEase domain	SMART	SM00471	hd_13	coord: 624..793 e-value: 1.4E-6 score: 37.9
IPR003607	HD/PDEase domain	CDD	cd00077	HDc	coord: 626..802 e-value: 3.71927E-16 score: 74.2981
IPR036971	3'5'-cyclic nucleotide phosphodiesterase, catalytic domain superfamily	GENE3D	G3DSA:1.10.1300.10		coord: 547..887 e-value: 1.2E-111 score: 374.8
IPR029016	GAF-like domain superfamily	GENE3D	G3DSA:3.30.450.40		coord: 352..520 e-value: 5.8E-55 score: 187.2
IPR029016	GAF-like domain superfamily	GENE3D	G3DSA:3.30.450.40		coord: 187..351 e-value: 1.4E-22 score: 81.9
IPR002073	3'5'-cyclic nucleotide phosphodiesterase, catalytic domain	PFAM	PF00233	PDEase_I	coord: 626..852 e-value: 1.3E-71 score: 241.1
IPR002073	3'5'-cyclic nucleotide phosphodiesterase, catalytic domain	PROSITE	PS51845	PDEASE_I_2	coord: 549..874 score: 108.788
IPR023174	3'5'-cyclic nucleotide phosphodiesterase, conserved site	PROSITE	PS00126	PDEASE_I_1	coord: 667..678