Adenylate kinase isoenzyme 5
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Overview
Neoblast Clusters
Zeng et. al., 2018
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny AppEmbryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30028060 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 2
Homology
BLAST of Adenylate kinase isoenzyme 5 vs. Ensembl Human
Match: AK5 (adenylate kinase 5 [Source:HGNC Symbol;Acc:HGNC:365]) HSP 1 Score: 114.775 bits (286), Expect = 1.612e-51 Identity = 87/326 (26.69%), Postives = 151/326 (46.32%), Query Frame = 1
Query: 664 EICMNRLSFVILVDCEEDTCQQALVQRPPIEGWTDHTPSAIGRRIANYKAYTLPVCKYFDDQQKLKMIDGDKTREEVLHDIG-----KIFKXXXXXXXXXXXXXXXXXXXXYNEIPPPGVA---QVQDIEEIFNIDPEIIRPSDLPQCPIVILLGGPGCGKTTAATEICTRYKDWVHINVNDIIRYRIFDKGVESTNWDCLAKLSLLNDVHLDQNQLVIEHWNINVEFIKEELKTLKSSTQGIILEGFPKDKVQLQQFNIEIGRADLVILLDCDEYYMTTRLLERGERLHRADDDLSNIKKRIIYYKTSGLPVCRYYDERHILNII 1617
+IC L V+ + C ++ L++R +G D A RR+ N+K P+ KYF ++ + D D+ +EV +DI K+F + + ++ + EI G Q D +F D DL +C I+ ++GGPG GK T ++ +Y + H++ +++R + + S L+ D+ +++ LV I +E +KE + T+G +++G+P++ Q ++F IG LVI +DC MT RLL+R DD I KR+ Y + +PV YY+ + L+ I
Sbjct: 233 QICTPDL--VVFLACANQRLKERLLKRAEQQGRPDDNVKATQRRLMNFKQNAAPLVKYFQEKGLIMTFDADRDEDEVFYDISMAVDNKLFPNKEAAAGSSDLDPSMILDT--GEIIDTGSDYEDQGDDQLNVFGEDTMGGFMEDLRKCKIIFIIGGPGSGKGTQCEKLVEKY-GFTHLSTGELLREELASESERS---------KLIRDI-MERGDLV--PSGIVLELLKEAMVASLGDTRGFLIDGYPREVKQGEEFGRRIGDPQLVICMDCSADTMTNRLLQRSRSSLPVDDTTKTIAKRLEAYYRASIPVIAYYETKTQLHKI 541 HSP 2 Score: 109.768 bits (273), Expect = 1.612e-51 Identity = 70/230 (30.43%), Postives = 115/230 (50.00%), Query Frame = 2
Query: 83 NAKDYLAKNEIPQLFECLMTGLMYHRPLSHIDYLQQCLDRIKK-QGVNGVRWDMFLEAKSIPLPPISPSCKE--------------------------EFTAEGVTD-SNTIQLNISYDV--------ALVIFIAGPGMDKKGLANILTKNYPRFYHVELGRLLREKAETEISKGISKWKVAASLMHCGELAPNDMVLETLIKELNYHTDVSGYIIEGYPRNLEQMQDFE 664
+AK+YLA+ EIPQLFE L+ GLM +P ++YL+ CL ++K+ G + V+WD F+ + LPP++ +F+ E TD S T +L Y+V +++ I GPG K + + + Y F ++ +G LLR+K + S KW + A ++ GELAP + + + ++L D G +I+G+PR++ Q FE
Sbjct: 5 DAKEYLARREIPQLFESLLNGLMCSKPEDPVEYLESCLQKVKELGGCDKVKWDTFVSQEKKTLPPLNGGQSRRSFLRNVMPENSNFPYRRYDRLPPIHQFSIESDTDLSETAELIEEYEVFDPTRPRPKIILVIGGPGSGKGTQSLKIAERYG-FQYISVGELLRKKIHSTSSN--RKWSLIAKIITTGELAPQETTITEIKQKLMQIPDEEGIVIDGFPRDVAQALSFE 231 HSP 3 Score: 100.523 bits (249), Expect = 2.070e-21 Identity = 63/223 (28.25%), Postives = 114/223 (51.12%), Query Frame = 1
Query: 1024 IEEIFNIDPEIIRPSDLPQCPIVILLGGPGCGKTTAATEICTRYKDWVHINVNDIIRYRIFDKGVESTNWDCLAKLSLLNDVHLDQNQLVIEHWNINVEFIKEELKTLKSSTQGIILEGFPKDKVQLQQFNIEIGRADLVILLDCDEYYMTTRLLERGERLHRADDDLSNIKKRIIYYKTSGLPVCRYYDERHILNIIPGDRKIAEVLADVISLLELAIMKNR 1692
IEE DP RP I++++GGPG GK T + +I RY + +I+V +++R +I + W +AK+ + +L + I IK++L + +GI+++GFP+D Q F +I DLV+ L C + RLL+R E+ R DD++ ++R++ +K + P+ +Y+ E+ ++ DR EV D+ ++ + N+
Sbjct: 119 IEEYEVFDPTRPRPK------IILVIGGPGSGKGTQSLKIAERY-GFQYISVGELLRKKIHSTS-SNRKWSLIAKI-------ITTGELAPQETTITE--IKQKLMQIPDE-EGIVIDGFPRDVAQALSFEDQICTPDLVVFLACANQRLKERLLKRAEQQGRPDDNVKATQRRLMNFKQNAAPLVKYFQEKGLIMTFDADRDEDEVFYDISMAVDNKLFPNK 323 HSP 4 Score: 56.9954 bits (136), Expect = 2.213e-14 Identity = 35/106 (33.02%), Postives = 58/106 (54.72%), Query Frame = 2
Query: 362 LVIFIAGPGMDKKGLANILTKNYPRFYHVELGRLLREKAETEISKGISKWKVAASLMHCGELAPNDMVLETLIKELNYHT--DVSGYIIEGYPRNLEQMQDFEKFV 673
++ I GPG K L + Y F H+ G LLRE E++ + K+ +M G+L P+ +VLE L+KE + D G++I+GYPR ++Q ++F + +
Sbjct: 378 IIFIIGGPGSGKGTQCEKLVEKYG-FTHLSTGELLRE----ELASESERSKLIRDIMERGDLVPSGIVLE-LLKEAMVASLGDTRGFLIDGYPREVKQGEEFGRRI 477 HSP 5 Score: 42.743 bits (99), Expect = 2.213e-14 Identity = 22/70 (31.43%), Postives = 35/70 (50.00%), Query Frame = 1
Query: 688 FVILVDCEEDTCQQALVQRPPIEGWTDHTPSAIGRRIANYKAYTLPVCKYFDDQQKLKMIDGDKTREEVL 897
VI +DC DT L+QR D T I +R+ Y ++PV Y++ + +L I+ + T E+V
Sbjct: 482 LVICMDCSADTMTNRLLQRSRSSLPVDDTTKTIAKRLEAYYRASIPVIAYYETKTQLHKINAEGTPEDVF 551
BLAST of Adenylate kinase isoenzyme 5 vs. Ensembl Human
Match: AK5 (adenylate kinase 5 [Source:HGNC Symbol;Acc:HGNC:365]) HSP 1 Score: 114.39 bits (285), Expect = 8.097e-42 Identity = 87/326 (26.69%), Postives = 151/326 (46.32%), Query Frame = 1
Query: 664 EICMNRLSFVILVDCEEDTCQQALVQRPPIEGWTDHTPSAIGRRIANYKAYTLPVCKYFDDQQKLKMIDGDKTREEVLHDIG-----KIFKXXXXXXXXXXXXXXXXXXXXYNEIPPPGVA---QVQDIEEIFNIDPEIIRPSDLPQCPIVILLGGPGCGKTTAATEICTRYKDWVHINVNDIIRYRIFDKGVESTNWDCLAKLSLLNDVHLDQNQLVIEHWNINVEFIKEELKTLKSSTQGIILEGFPKDKVQLQQFNIEIGRADLVILLDCDEYYMTTRLLERGERLHRADDDLSNIKKRIIYYKTSGLPVCRYYDERHILNII 1617
+IC L V+ + C ++ L++R +G D A RR+ N+K P+ KYF ++ + D D+ +EV +DI K+F + + ++ + EI G Q D +F D DL +C I+ ++GGPG GK T ++ +Y + H++ +++R + + S L+ D+ +++ LV I +E +KE + T+G +++G+P++ Q ++F IG LVI +DC MT RLL+R DD I KR+ Y + +PV YY+ + L+ I
Sbjct: 207 QICTPDL--VVFLACANQRLKERLLKRAEQQGRPDDNVKATQRRLMNFKQNAAPLVKYFQEKGLIMTFDADRDEDEVFYDISMAVDNKLFPNKEAAAGSSDLDPSMILDT--GEIIDTGSDYEDQGDDQLNVFGEDTMGGFMEDLRKCKIIFIIGGPGSGKGTQCEKLVEKY-GFTHLSTGELLREELASESERS---------KLIRDI-MERGDLV--PSGIVLELLKEAMVASLGDTRGFLIDGYPREVKQGEEFGRRIGDPQLVICMDCSADTMTNRLLQRSRSSLPVDDTTKTIAKRLEAYYRASIPVIAYYETKTQLHKI 515 HSP 2 Score: 77.411 bits (189), Expect = 8.097e-42 Identity = 55/208 (26.44%), Postives = 96/208 (46.15%), Query Frame = 2
Query: 149 MYHRPLSHIDYLQQCLDRIKK-QGVNGVRWDMFLEAKSIPLPPISPSCKE--------------------------EFTAEGVTD-SNTIQLNISYDV--------ALVIFIAGPGMDKKGLANILTKNYPRFYHVELGRLLREKAETEISKGISKWKVAASLMHCGELAPNDMVLETLIKELNYHTDVSGYIIEGYPRNLEQMQDFE 664
M +P ++YL+ CL ++K+ G + V+WD F+ + LPP++ +F+ E TD S T +L Y+V +++ I GPG K + + + Y F ++ +G LLR+K + S KW + A ++ GELAP + + + ++L D G +I+G+PR++ Q FE
Sbjct: 1 MCSKPEDPVEYLESCLQKVKELGGCDKVKWDTFVSQEKKTLPPLNGGQSRRSFLRNVMPENSNFPYRRYDRLPPIHQFSIESDTDLSETAELIEEYEVFDPTRPRPKIILVIGGPGSGKGTQSLKIAERYG-FQYISVGELLRKKIHSTSSN--RKWSLIAKIITTGELAPQETTITEIKQKLMQIPDEEGIVIDGFPRDVAQALSFE 205 HSP 3 Score: 100.523 bits (249), Expect = 1.927e-21 Identity = 63/223 (28.25%), Postives = 114/223 (51.12%), Query Frame = 1
Query: 1024 IEEIFNIDPEIIRPSDLPQCPIVILLGGPGCGKTTAATEICTRYKDWVHINVNDIIRYRIFDKGVESTNWDCLAKLSLLNDVHLDQNQLVIEHWNINVEFIKEELKTLKSSTQGIILEGFPKDKVQLQQFNIEIGRADLVILLDCDEYYMTTRLLERGERLHRADDDLSNIKKRIIYYKTSGLPVCRYYDERHILNIIPGDRKIAEVLADVISLLELAIMKNR 1692
IEE DP RP I++++GGPG GK T + +I RY + +I+V +++R +I + W +AK+ + +L + I IK++L + +GI+++GFP+D Q F +I DLV+ L C + RLL+R E+ R DD++ ++R++ +K + P+ +Y+ E+ ++ DR EV D+ ++ + N+
Sbjct: 93 IEEYEVFDPTRPRPK------IILVIGGPGSGKGTQSLKIAERY-GFQYISVGELLRKKIHSTS-SNRKWSLIAKI-------ITTGELAPQETTITE--IKQKLMQIPDE-EGIVIDGFPRDVAQALSFEDQICTPDLVVFLACANQRLKERLLKRAEQQGRPDDNVKATQRRLMNFKQNAAPLVKYFQEKGLIMTFDADRDEDEVFYDISMAVDNKLFPNK 297 HSP 4 Score: 56.6102 bits (135), Expect = 3.148e-14 Identity = 35/106 (33.02%), Postives = 58/106 (54.72%), Query Frame = 2
Query: 362 LVIFIAGPGMDKKGLANILTKNYPRFYHVELGRLLREKAETEISKGISKWKVAASLMHCGELAPNDMVLETLIKELNYHT--DVSGYIIEGYPRNLEQMQDFEKFV 673
++ I GPG K L + Y F H+ G LLRE E++ + K+ +M G+L P+ +VLE L+KE + D G++I+GYPR ++Q ++F + +
Sbjct: 352 IIFIIGGPGSGKGTQCEKLVEKYG-FTHLSTGELLRE----ELASESERSKLIRDIMERGDLVPSGIVLE-LLKEAMVASLGDTRGFLIDGYPREVKQGEEFGRRI 451 HSP 5 Score: 42.743 bits (99), Expect = 3.148e-14 Identity = 22/70 (31.43%), Postives = 35/70 (50.00%), Query Frame = 1
Query: 688 FVILVDCEEDTCQQALVQRPPIEGWTDHTPSAIGRRIANYKAYTLPVCKYFDDQQKLKMIDGDKTREEVL 897
VI +DC DT L+QR D T I +R+ Y ++PV Y++ + +L I+ + T E+V
Sbjct: 456 LVICMDCSADTMTNRLLQRSRSSLPVDDTTKTIAKRLEAYYRASIPVIAYYETKTQLHKINAEGTPEDVF 525
BLAST of Adenylate kinase isoenzyme 5 vs. Ensembl Human
Match: AK1 (adenylate kinase 1 [Source:HGNC Symbol;Acc:HGNC:361]) HSP 1 Score: 90.8929 bits (224), Expect = 2.533e-20 Identity = 54/200 (27.00%), Postives = 107/200 (53.50%), Query Frame = 1
Query: 1072 LPQCPIVILLGGPGCGKTTAATEICTRYKDWVHINVNDIIRYRIFDKGVESTNWDCLAKLSLLNDVHLDQNQLVIEHWNINVEFIKEELKTLKSSTQGIILEGFPKDKVQLQQFNIEIGRADLVILLDCDEYYMTTRLLERGERLHRADDDLSNIKKRIIYYKTSGLPVCRYYDERHILNIIPGDRKIAEVLADVISLLE 1671
L + I+ ++GGPG GK T +I +Y + H++ D++R + S+ KLS + +++ QLV ++ +++ + ++++G +++G+P++ Q ++F IG+ L++ +D MT RLL+RGE R DD+ IKKR+ Y + PV +Y++R I+ + + + V + V + L+
Sbjct: 5 LKKTKIIFVVGGPGSGKGTQCEKIVQKY-GYTHLSTGDLLRSEV------SSGSARGKKLSEI----MEKGQLV--PLETVLDMLRDAMVAKVNTSKGFLIDGYPREVQQGEEFERRIGQPTLLLYVDAGPETMTQRLLKRGETSGRVDDNEETIKKRLETYYKATEPVIAFYEKRGIVRKVNAEGSVDSVFSQVCTHLD 191 HSP 2 Score: 57.3806 bits (137), Expect = 1.000e-8 Identity = 31/105 (29.52%), Postives = 58/105 (55.24%), Query Frame = 2
Query: 362 LVIFIAGPGMDKKGLANILTKNYPRFYHVELGRLLREKAETEISKGISKWKVAASLMHCGELAPNDMVLETLIKELNYHTDVS-GYIIEGYPRNLEQMQDFEKFV 673
++ + GPG K + + Y + H+ G LLR +E+S G ++ K + +M G+L P + VL+ L + + S G++I+GYPR ++Q ++FE+ +
Sbjct: 10 IIFVVGGPGSGKGTQCEKIVQKYG-YTHLSTGDLLR----SEVSSGSARGKKLSEIMEKGQLVPLETVLDMLRDAMVAKVNTSKGFLIDGYPREVQQGEEFERRI 109
BLAST of Adenylate kinase isoenzyme 5 vs. Ensembl Human
Match: AK1 (adenylate kinase 1 [Source:HGNC Symbol;Acc:HGNC:361]) HSP 1 Score: 90.8929 bits (224), Expect = 2.533e-20 Identity = 54/200 (27.00%), Postives = 107/200 (53.50%), Query Frame = 1
Query: 1072 LPQCPIVILLGGPGCGKTTAATEICTRYKDWVHINVNDIIRYRIFDKGVESTNWDCLAKLSLLNDVHLDQNQLVIEHWNINVEFIKEELKTLKSSTQGIILEGFPKDKVQLQQFNIEIGRADLVILLDCDEYYMTTRLLERGERLHRADDDLSNIKKRIIYYKTSGLPVCRYYDERHILNIIPGDRKIAEVLADVISLLE 1671
L + I+ ++GGPG GK T +I +Y + H++ D++R + S+ KLS + +++ QLV ++ +++ + ++++G +++G+P++ Q ++F IG+ L++ +D MT RLL+RGE R DD+ IKKR+ Y + PV +Y++R I+ + + + V + V + L+
Sbjct: 5 LKKTKIIFVVGGPGSGKGTQCEKIVQKY-GYTHLSTGDLLRSEV------SSGSARGKKLSEI----MEKGQLV--PLETVLDMLRDAMVAKVNTSKGFLIDGYPREVQQGEEFERRIGQPTLLLYVDAGPETMTQRLLKRGETSGRVDDNEETIKKRLETYYKATEPVIAFYEKRGIVRKVNAEGSVDSVFSQVCTHLD 191 HSP 2 Score: 57.3806 bits (137), Expect = 1.000e-8 Identity = 31/105 (29.52%), Postives = 58/105 (55.24%), Query Frame = 2
Query: 362 LVIFIAGPGMDKKGLANILTKNYPRFYHVELGRLLREKAETEISKGISKWKVAASLMHCGELAPNDMVLETLIKELNYHTDVS-GYIIEGYPRNLEQMQDFEKFV 673
++ + GPG K + + Y + H+ G LLR +E+S G ++ K + +M G+L P + VL+ L + + S G++I+GYPR ++Q ++FE+ +
Sbjct: 10 IIFVVGGPGSGKGTQCEKIVQKYG-YTHLSTGDLLR----SEVSSGSARGKKLSEIMEKGQLVPLETVLDMLRDAMVAKVNTSKGFLIDGYPREVQQGEEFERRI 109
BLAST of Adenylate kinase isoenzyme 5 vs. Ensembl Human
Match: AK1 (adenylate kinase 1 [Source:HGNC Symbol;Acc:HGNC:361]) HSP 1 Score: 90.5077 bits (223), Expect = 5.058e-20 Identity = 54/200 (27.00%), Postives = 107/200 (53.50%), Query Frame = 1
Query: 1072 LPQCPIVILLGGPGCGKTTAATEICTRYKDWVHINVNDIIRYRIFDKGVESTNWDCLAKLSLLNDVHLDQNQLVIEHWNINVEFIKEELKTLKSSTQGIILEGFPKDKVQLQQFNIEIGRADLVILLDCDEYYMTTRLLERGERLHRADDDLSNIKKRIIYYKTSGLPVCRYYDERHILNIIPGDRKIAEVLADVISLLE 1671
L + I+ ++GGPG GK T +I +Y + H++ D++R + S+ KLS + +++ QLV ++ +++ + ++++G +++G+P++ Q ++F IG+ L++ +D MT RLL+RGE R DD+ IKKR+ Y + PV +Y++R I+ + + + V + V + L+
Sbjct: 21 LKKTKIIFVVGGPGSGKGTQCEKIVQKY-GYTHLSTGDLLRSEV------SSGSARGKKLSEI----MEKGQLV--PLETVLDMLRDAMVAKVNTSKGFLIDGYPREVQQGEEFERRIGQPTLLLYVDAGPETMTQRLLKRGETSGRVDDNEETIKKRLETYYKATEPVIAFYEKRGIVRKVNAEGSVDSVFSQVCTHLD 207 HSP 2 Score: 57.7658 bits (138), Expect = 8.584e-9 Identity = 31/105 (29.52%), Postives = 58/105 (55.24%), Query Frame = 2
Query: 362 LVIFIAGPGMDKKGLANILTKNYPRFYHVELGRLLREKAETEISKGISKWKVAASLMHCGELAPNDMVLETLIKELNYHTDVS-GYIIEGYPRNLEQMQDFEKFV 673
++ + GPG K + + Y + H+ G LLR +E+S G ++ K + +M G+L P + VL+ L + + S G++I+GYPR ++Q ++FE+ +
Sbjct: 26 IIFVVGGPGSGKGTQCEKIVQKYG-YTHLSTGDLLR----SEVSSGSARGKKLSEIMEKGQLVPLETVLDMLRDAMVAKVNTSKGFLIDGYPREVQQGEEFERRI 125
BLAST of Adenylate kinase isoenzyme 5 vs. Ensembl Celegans
Match: F38B2.4 (Adenylate kinase isoenzyme 1 [Source:UniProtKB/Swiss-Prot;Acc:Q20140]) HSP 1 Score: 98.2117 bits (243), Expect = 4.219e-23 Identity = 60/211 (28.44%), Postives = 102/211 (48.34%), Query Frame = 1
Query: 1057 IRPSDLPQCPIVILLGGPGCGKTTAATEICTRYKDWVHINVNDIIRYRIFDKGVESTNWDCLAKLSLLNDVHLDQNQLVIEHWNINVEFIKEE-LKTLKSSTQGIILEGFPKDKVQLQQFNIEIGRADLVILLDCDEYYMTTRLLERGERLHRADDDLSNIKKRIIYYKTSGLPVCRYYDERHILNIIPGDRKIAEVLADVISLLELAIMK 1686
+ P PI ++GGPG GK T +I +Y H++ D++R + + ++ LV + ++ +KE LK ++ ++G +++G+P++ Q QQF EI A LV+ D E + RLL R + RADD+ IKKR+ + TS PV YY+ + L I + + ++ A V++ L+ A K
Sbjct: 12 LAPLKAAGVPIFFIVGGPGSGKGTQCDKIVAKY-GLTHLSSGDLLRDEVKSGSPRGAQLTAI----------MESGALV--PLEVVLDLVKEAMLKAIEKGSKGFLIDGYPREVAQGQQFESEIQEAKLVLFFDVAEETLVKRLLHRAQTSGRADDNADTIKKRLHTFVTSTAPVVDYYESKGKLVRINAEGSVDDIFAVVVANLDKATSK 209 HSP 2 Score: 47.7506 bits (112), Expect = 8.875e-6 Identity = 32/106 (30.19%), Postives = 50/106 (47.17%), Query Frame = 2
Query: 356 VALVIFIAGPGMDKKGLANILTKNYPRFYHVELGRLLREKAETEISKGISKWKVAASLMHCGELAPNDMVLETLIKEL---NYHTDVSGYIIEGYPRNLEQMQDFE 664
V + + GPG K + + Y H+ G LLR+ E+ G + ++M G L P ++VL+ L+KE G++I+GYPR + Q Q FE
Sbjct: 20 VPIFFIVGGPGSGKGTQCDKIVAKYG-LTHLSSGDLLRD----EVKSGSPRGAQLTAIMESGALVPLEVVLD-LVKEAMLKAIEKGSKGFLIDGYPREVAQGQQFE 119
BLAST of Adenylate kinase isoenzyme 5 vs. Ensembl Celegans
Match: F13E6.2 (pep chromosome:WBcel235:X:10668280:10674293:-1 gene:WBGene00008746.1 transcript:F13E6.2.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:F13E6.2) HSP 1 Score: 90.8929 bits (224), Expect = 1.283e-18 Identity = 55/211 (26.07%), Postives = 105/211 (49.76%), Query Frame = 1
Query: 1051 EIIRPSDLPQ-CPIVILLGGPGCGKTTAATEICTRYKDWVHINVNDIIRYRIFDKGVESTNWDCLAKLSLLNDVHLDQNQLVIEHWNINVEFIKEELKTLKSSTQGIILEGFPKDKVQLQQFNIEIGRADLVILLDCDEYYMTTRLLERGERLHRADDDLSNIKKRIIYYKTSGLPVCRYYDERHILNIIPGDRKIAEVLADVISLLELAI 1680
E+ P LP P++++LG PG K + I +Y + +++ DI+R +I ++ + WD ++K ++ + V + EEL + +S G ++EG+PK QL + R DL IL+DC E + + +R R+DDD ++ R+ Y+K + LP+ + D++ L ++ GD V +V+ +++ +
Sbjct: 502 ELGEPVGLPNNAPVILVLGAPGSQKNDISRRIAQKYDGFTMLSMGDILRKKINNEKNDEM-WDKVSK-------KMNNGDPIPTKMCRTVLY--EELHSRGTSNWGYVIEGYPKSPDQLVDLEHSLQRTDLAILIDCTEQFCLEVINKRNRENKRSDDDSDAVRSRMEYFKKNTLPMLKTLDDKGKLRVVDGDADPDTVFKEVVQVIDRTL 702 HSP 2 Score: 54.299 bits (129), Expect = 2.730e-16 Identity = 30/105 (28.57%), Postives = 53/105 (50.48%), Query Frame = 2
Query: 353 DVALVIFIAGPGMDKKGLANILTKNYPRFYHVELGRLLREKAETEISKGISKWKVAASLMHCGELAPNDMVLETLIKELNYH-TDVSGYIIEGYPRNLEQMQDFE 664
+ +++ + PG K ++ + + Y F + +G +LR+K E K W + M+ G+ P M L +EL+ T GY+IEGYP++ +Q+ D E
Sbjct: 512 NAPVILVLGAPGSQKNDISRRIAQKYDGFTMLSMGDILRKKINNE--KNDEMWDKVSKKMNNGDPIPTKMCRTVLYEELHSRGTSNWGYVIEGYPKSPDQLVDLE 614 HSP 3 Score: 50.8322 bits (120), Expect = 2.730e-16 Identity = 25/85 (29.41%), Postives = 44/85 (51.76%), Query Frame = 1
Query: 664 EICMNRLSFVILVDCEEDTCQQALVQRPPIEGWTDHTPSAIGRRIANYKAYTLPVCKYFDDQQKLKMIDGDKTREEVLHDIGKIF 918
E + R IL+DC E C + + +R +D A+ R+ +K TLP+ K DD+ KL+++DGD + V ++ ++
Sbjct: 614 EHSLQRTDLAILIDCTEQFCLEVINKRNRENKRSDDDSDAVRSRMEYFKKNTLPMLKTLDDKGKLRVVDGDADPDTVFKEVVQVI 698 HSP 4 Score: 77.7962 bits (190), Expect = 1.339e-14 Identity = 52/199 (26.13%), Postives = 95/199 (47.74%), Query Frame = 1
Query: 1048 PEIIRPSD---LPQCPIVILLGGPGCGKTTAATEICTRYKD--WVHINVNDIIRYRIFDKGVESTNWDCLAKLSLLNDVHLDQNQLVIEHWNINVEFIKEELKTLKSSTQGIILEGFPKDKVQLQQFNIEIGRADLVILLDCDEYYMTTRLLERGERLHRADDDLSNIKKRIIYYKTSGLPVCRYYDERHILNIIPGDR 1629
P + R ++ +P PI++ +GGPG GKT A + D VHI + DIIR + + W + + + L NQL + +K E+ G LEG+P++ Q++ F ++ ++ ++LD DE + + RG + I ++I +K LP +Y+D++ +L++IPG++
Sbjct: 155 PSVTRAAEVARIPDVPIILFMGGPGGGKTRHAARVADSLADNGLVHICMPDIIRTALGKYKDKYPEWKEANEHYIRGE--LIPNQLALT-------LLKAEMGR-HPDAMGFFLEGYPREARQVEDFERQVKSVNMALILDYDERTLREHMERRGL-------GMEIIDQKIKEFKQKTLPSAKYFDDQKLLHLIPGEK 336 HSP 5 Score: 60.077 bits (144), Expect = 5.766e-14 Identity = 37/111 (33.33%), Postives = 56/111 (50.45%), Query Frame = 2
Query: 353 DVALVIFIAGPGMDKKG----LANILTKNYPRFYHVELGRLLREKAETEISKGISKWKVAASLMHCGELAPNDMVLETLIKELNYHTDVSGYIIEGYPRNLEQMQDFEKFV 673
DV +++F+ GPG K +A+ L N H+ + ++R A + +WK A GEL PN + L L E+ H D G+ +EGYPR Q++DFE+ V
Sbjct: 168 DVPIILFMGGPGGGKTRHAARVADSLADNG--LVHICMPDIIR-TALGKYKDKYPEWKEANEHYIRGELIPNQLALTLLKAEMGRHPDAMGFFLEGYPREARQVEDFERQV 275 HSP 6 Score: 36.965 bits (84), Expect = 5.766e-14 Identity = 16/32 (50.00%), Postives = 22/32 (68.75%), Query Frame = 1
Query: 784 IGRRIANYKAYTLPVCKYFDDQQKLKMIDGDK 879
I ++I +K TLP KYFDDQ+ L +I G+K
Sbjct: 305 IDQKIKEFKQKTLPSAKYFDDQKLLHLIPGEK 336 HSP 7 Score: 55.8398 bits (133), Expect = 9.050e-8 Identity = 24/60 (40.00%), Postives = 38/60 (63.33%), Query Frame = 2
Query: 68 LATPRNAKDYLAKNEIPQLFECLMTGLMYHRPLSHIDYLQQCLDRIKKQGVNGVRWDMFL 247
++ P A+ YL + IPQLFE LMTGL+Y RP + +L++ + +I+ + WDMF+
Sbjct: 1 MSGPSEARIYLQDHRIPQLFEGLMTGLIYSRPADPLKFLEESIVKIRSTPGITLSWDMFI 60
BLAST of Adenylate kinase isoenzyme 5 vs. Ensembl Celegans
Match: F40F8.1 (UMP-CMP kinase 2 [Source:UniProtKB/Swiss-Prot;Acc:Q20230]) HSP 1 Score: 69.3218 bits (168), Expect = 3.231e-13 Identity = 52/206 (25.24%), Postives = 98/206 (47.57%), Query Frame = 1
Query: 1087 IVILLGGPGCGKTTAATEICTRYK---DWVHINVNDIIRYRIFDKGVESTNWDCLAKLSLLNDVHLDQNQLVIEHWNINVEFIKEELKTLKSSTQGIILEGFPKDKVQLQQFNIEI-GRA--DLVILLDCDEYYMTTRLLERGERLHRADDDLSNIKKRIIYYKTSGLPVCRYYDERHILNIIPGDRKIAEVLADVISLLELAIMK 1686
+V +LG PG GK T IC + + ++VH++ D++R +G E L + H+ +V I ++ +K +G +++GFP+++ LQ +N ++ G+A V+ L C R L RG+ R DD+ ++KKR+ Y P+ ++++ ++ + +R + V ADV + + A K
Sbjct: 4 VVFVLGPPGSGKGT----ICAKIQENLNYVHLSAGDLLRAERQREGSE---------FGALIESHIKNGSIV--PVEITCSLLENAMKAC-GDAKGFLVDGFPRNEDNLQGWNKQMDGKALVQFVLFLSCPVSICIERCLNRGQ--GRTDDNEESLKKRVETYNQQTFPIIEHFEKSGLVREVKSERPVDVVYADVEKVFDAANKK 191 HSP 2 Score: 43.1282 bits (100), Expect = 4.055e-9 Identity = 25/101 (24.75%), Postives = 46/101 (45.54%), Query Frame = 2
Query: 365 VIFIAGPGMDKKGLANILTKNYPRFYHVELGRLLREKAETEISKGISKWKVAASLMHCGELAPNDMVLETLIKELNYHTDVSGYIIEGYPRNLEQMQDFEK 667
V+F+ GP KG + + H+ G LLR + + E G + S + G + P ++ L + D G++++G+PRN + +Q + K
Sbjct: 4 VVFVLGPPGSGKGTICAKIQENLNYVHLSAGDLLRAERQRE---GSEFGALIESHIKNGSIVPVEITCSLLENAMKACGDAKGFLVDGFPRNEDNLQGWNK 101 HSP 3 Score: 37.3502 bits (85), Expect = 4.055e-9 Identity = 17/79 (21.52%), Postives = 39/79 (49.37%), Query Frame = 1
Query: 682 LSFVILVDCEEDTCQQALVQRPPIEGWTDHTPSAIGRRIANYKAYTLPVCKYFDDQQKLKMIDGDKTREEVLHDIGKIF 918
+ FV+ + C C + + R +G TD ++ +R+ Y T P+ ++F+ ++ + ++ + V D+ K+F
Sbjct: 109 VQFVLFLSCPVSICIERCLNRG--QGRTDDNEESLKKRVETYNQQTFPIIEHFEKSGLVREVKSERPVDVVYADVEKVF 185
BLAST of Adenylate kinase isoenzyme 5 vs. Ensembl Celegans
Match: F40F8.1 (UMP-CMP kinase 2 [Source:UniProtKB/Swiss-Prot;Acc:Q20230]) HSP 1 Score: 69.3218 bits (168), Expect = 3.231e-13 Identity = 52/206 (25.24%), Postives = 98/206 (47.57%), Query Frame = 1
Query: 1087 IVILLGGPGCGKTTAATEICTRYK---DWVHINVNDIIRYRIFDKGVESTNWDCLAKLSLLNDVHLDQNQLVIEHWNINVEFIKEELKTLKSSTQGIILEGFPKDKVQLQQFNIEI-GRA--DLVILLDCDEYYMTTRLLERGERLHRADDDLSNIKKRIIYYKTSGLPVCRYYDERHILNIIPGDRKIAEVLADVISLLELAIMK 1686
+V +LG PG GK T IC + + ++VH++ D++R +G E L + H+ +V I ++ +K +G +++GFP+++ LQ +N ++ G+A V+ L C R L RG+ R DD+ ++KKR+ Y P+ ++++ ++ + +R + V ADV + + A K
Sbjct: 4 VVFVLGPPGSGKGT----ICAKIQENLNYVHLSAGDLLRAERQREGSE---------FGALIESHIKNGSIV--PVEITCSLLENAMKAC-GDAKGFLVDGFPRNEDNLQGWNKQMDGKALVQFVLFLSCPVSICIERCLNRGQ--GRTDDNEESLKKRVETYNQQTFPIIEHFEKSGLVREVKSERPVDVVYADVEKVFDAANKK 191 HSP 2 Score: 43.1282 bits (100), Expect = 4.055e-9 Identity = 25/101 (24.75%), Postives = 46/101 (45.54%), Query Frame = 2
Query: 365 VIFIAGPGMDKKGLANILTKNYPRFYHVELGRLLREKAETEISKGISKWKVAASLMHCGELAPNDMVLETLIKELNYHTDVSGYIIEGYPRNLEQMQDFEK 667
V+F+ GP KG + + H+ G LLR + + E G + S + G + P ++ L + D G++++G+PRN + +Q + K
Sbjct: 4 VVFVLGPPGSGKGTICAKIQENLNYVHLSAGDLLRAERQRE---GSEFGALIESHIKNGSIVPVEITCSLLENAMKACGDAKGFLVDGFPRNEDNLQGWNK 101 HSP 3 Score: 37.3502 bits (85), Expect = 4.055e-9 Identity = 17/79 (21.52%), Postives = 39/79 (49.37%), Query Frame = 1
Query: 682 LSFVILVDCEEDTCQQALVQRPPIEGWTDHTPSAIGRRIANYKAYTLPVCKYFDDQQKLKMIDGDKTREEVLHDIGKIF 918
+ FV+ + C C + + R +G TD ++ +R+ Y T P+ ++F+ ++ + ++ + V D+ K+F
Sbjct: 109 VQFVLFLSCPVSICIERCLNRG--QGRTDDNEESLKKRVETYNQQTFPIIEHFEKSGLVREVKSERPVDVVYADVEKVF 185
BLAST of Adenylate kinase isoenzyme 5 vs. Ensembl Celegans
Match: F40F8.1 (UMP-CMP kinase 2 [Source:UniProtKB/Swiss-Prot;Acc:Q20230]) HSP 1 Score: 69.3218 bits (168), Expect = 3.231e-13 Identity = 52/206 (25.24%), Postives = 98/206 (47.57%), Query Frame = 1
Query: 1087 IVILLGGPGCGKTTAATEICTRYK---DWVHINVNDIIRYRIFDKGVESTNWDCLAKLSLLNDVHLDQNQLVIEHWNINVEFIKEELKTLKSSTQGIILEGFPKDKVQLQQFNIEI-GRA--DLVILLDCDEYYMTTRLLERGERLHRADDDLSNIKKRIIYYKTSGLPVCRYYDERHILNIIPGDRKIAEVLADVISLLELAIMK 1686
+V +LG PG GK T IC + + ++VH++ D++R +G E L + H+ +V I ++ +K +G +++GFP+++ LQ +N ++ G+A V+ L C R L RG+ R DD+ ++KKR+ Y P+ ++++ ++ + +R + V ADV + + A K
Sbjct: 4 VVFVLGPPGSGKGT----ICAKIQENLNYVHLSAGDLLRAERQREGSE---------FGALIESHIKNGSIV--PVEITCSLLENAMKAC-GDAKGFLVDGFPRNEDNLQGWNKQMDGKALVQFVLFLSCPVSICIERCLNRGQ--GRTDDNEESLKKRVETYNQQTFPIIEHFEKSGLVREVKSERPVDVVYADVEKVFDAANKK 191 HSP 2 Score: 43.1282 bits (100), Expect = 4.055e-9 Identity = 25/101 (24.75%), Postives = 46/101 (45.54%), Query Frame = 2
Query: 365 VIFIAGPGMDKKGLANILTKNYPRFYHVELGRLLREKAETEISKGISKWKVAASLMHCGELAPNDMVLETLIKELNYHTDVSGYIIEGYPRNLEQMQDFEK 667
V+F+ GP KG + + H+ G LLR + + E G + S + G + P ++ L + D G++++G+PRN + +Q + K
Sbjct: 4 VVFVLGPPGSGKGTICAKIQENLNYVHLSAGDLLRAERQRE---GSEFGALIESHIKNGSIVPVEITCSLLENAMKACGDAKGFLVDGFPRNEDNLQGWNK 101 HSP 3 Score: 37.3502 bits (85), Expect = 4.055e-9 Identity = 17/79 (21.52%), Postives = 39/79 (49.37%), Query Frame = 1
Query: 682 LSFVILVDCEEDTCQQALVQRPPIEGWTDHTPSAIGRRIANYKAYTLPVCKYFDDQQKLKMIDGDKTREEVLHDIGKIF 918
+ FV+ + C C + + R +G TD ++ +R+ Y T P+ ++F+ ++ + ++ + V D+ K+F
Sbjct: 109 VQFVLFLSCPVSICIERCLNRG--QGRTDDNEESLKKRVETYNQQTFPIIEHFEKSGLVREVKSERPVDVVYADVEKVF 185
BLAST of Adenylate kinase isoenzyme 5 vs. Ensembl Fly
Match: Adk1 (gene:FBgn0022709 transcript:FBtr0076017) HSP 1 Score: 78.9518 bits (193), Expect = 1.824e-16 Identity = 51/208 (24.52%), Postives = 101/208 (48.56%), Query Frame = 1
Query: 1084 PIVILLGGPGCGKTTAATEICTRYKDWVHINVNDIIRYRIF---DKGVESTNWDCLAKLSLLNDVHLDQNQLVIEHWNINVEFIKEELKTLKSSTQGIILEGFPKDKVQLQQFNIEIGRADLVILLDCDEYYMTTRLLER--GERLHRADDDLSNIKKRIIYYKTSGLPVCRYYDERHILNIIPGDRKIAEVLADVISLLELAIMKNR 1692
PI+ +LGGPGCGK T +I +Y + H++ D++R + DKG + +++ L N V+ N + + K S++G +++G+P+ K Q +F I ADL + +C E M R++ R + R DD+ I+ R++ +K + + Y+ + + I +R + ++ +V+ ++ + K +
Sbjct: 5 PIIWILGGPGCGKGTQCAKIVEKY-GFTHLSSGDLLRNEVASGSDKGRQLQ--------AVMASGGLVSNDEVLSLLN-------DAITRAKGSSKGFLIDGYPRQKNQGIEFEARIAPADLALYFECSEDTMVQRIMARAAASAVKRDDDNEKTIRARLLTFKQNTNAILELYEPKTL--TINAERDVDDIFLEVVQAIDCVLKKKQ 194 HSP 2 Score: 50.0618 bits (118), Expect = 1.390e-6 Identity = 33/105 (31.43%), Postives = 50/105 (47.62%), Query Frame = 2
Query: 353 DVALVIFIAGPGMDKKGLANILTKNYPRFYHVELGRLLREKAETEISKGISKWKVAASLMHCGELAPNDMVLETLIKELNYHTDVS-GYIIEGYPRNLEQMQDFE 664
D+ ++ + GPG K + + Y F H+ G LLR E++ G K + ++M G L ND VL L + S G++I+GYPR Q +FE
Sbjct: 3 DIPIIWILGGPGCGKGTQCAKIVEKYG-FTHLSSGDLLR----NEVASGSDKGRQLQAVMASGGLVSNDEVLSLLNDAITRAKGSSKGFLIDGYPRQKNQGIEFE 102
BLAST of Adenylate kinase isoenzyme 5 vs. Ensembl Fly
Match: Adk1 (gene:FBgn0022709 transcript:FBtr0076018) HSP 1 Score: 78.5666 bits (192), Expect = 4.363e-16 Identity = 51/208 (24.52%), Postives = 101/208 (48.56%), Query Frame = 1
Query: 1084 PIVILLGGPGCGKTTAATEICTRYKDWVHINVNDIIRYRIF---DKGVESTNWDCLAKLSLLNDVHLDQNQLVIEHWNINVEFIKEELKTLKSSTQGIILEGFPKDKVQLQQFNIEIGRADLVILLDCDEYYMTTRLLER--GERLHRADDDLSNIKKRIIYYKTSGLPVCRYYDERHILNIIPGDRKIAEVLADVISLLELAIMKNR 1692
PI+ +LGGPGCGK T +I +Y + H++ D++R + DKG + +++ L N V+ N + + K S++G +++G+P+ K Q +F I ADL + +C E M R++ R + R DD+ I+ R++ +K + + Y+ + + I +R + ++ +V+ ++ + K +
Sbjct: 33 PIIWILGGPGCGKGTQCAKIVEKY-GFTHLSSGDLLRNEVASGSDKGRQLQ--------AVMASGGLVSNDEVLSLLN-------DAITRAKGSSKGFLIDGYPRQKNQGIEFEARIAPADLALYFECSEDTMVQRIMARAAASAVKRDDDNEKTIRARLLTFKQNTNAILELYEPKTL--TINAERDVDDIFLEVVQAIDCVLKKKQ 222 HSP 2 Score: 50.447 bits (119), Expect = 1.606e-6 Identity = 33/107 (30.84%), Postives = 51/107 (47.66%), Query Frame = 2
Query: 347 SYDVALVIFIAGPGMDKKGLANILTKNYPRFYHVELGRLLREKAETEISKGISKWKVAASLMHCGELAPNDMVLETLIKELNYHTDVS-GYIIEGYPRNLEQMQDFE 664
+ D+ ++ + GPG K + + Y F H+ G LLR E++ G K + ++M G L ND VL L + S G++I+GYPR Q +FE
Sbjct: 29 AADIPIIWILGGPGCGKGTQCAKIVEKYG-FTHLSSGDLLR----NEVASGSDKGRQLQAVMASGGLVSNDEVLSLLNDAITRAKGSSKGFLIDGYPRQKNQGIEFE 130
BLAST of Adenylate kinase isoenzyme 5 vs. Ensembl Fly
Match: Dak1 (gene:FBgn0028833 transcript:FBtr0084976) HSP 1 Score: 72.7886 bits (177), Expect = 6.289e-14 Identity = 51/194 (26.29%), Postives = 90/194 (46.39%), Query Frame = 1
Query: 1087 IVILLGGPGCGKTTAATEICTRYKDWVHINVNDIIRYRIFDKGVESTNWDCLAKLSLLNDVHLDQNQLVIEHWNINVEFIKEELKTLKSSTQGIILEGFPKDKVQLQQFNIEIGRA---DLVILLDCDEYYMTTRLLERGER-LHRADDDLSNIKKRIIYYKTSGLPVCRYYDERHILNIIPGDRKIAEVLADV 1656
IV +LGGPG GK T + I R++ + H++ D++R +G E N L+ D + + +E + ++ +K S +++GFP+++ L +N ++ V+ DC E R L RG+ R DD+L ++KKRI Y LP+ ++++ + I EV +V
Sbjct: 65 IVFVLGGPGAGKGTQCSRIVDRFQ-FTHLSAGDLLREERSREGSEFGN--------LIEDYIRNGKIVPVE---VTCSLLENAMKA--SGKSRFLIDGFPRNQDNLDGWNRQMSEKVDFQFVLFFDCGEDVCVKRCLGRGQSGSGRTDDNLDSLKKRISTYNNDSLPIIKFFEGAGQVKRIDASPDAEEVFGEV 244 HSP 2 Score: 53.5286 bits (127), Expect = 1.268e-11 Identity = 27/80 (33.75%), Postives = 43/80 (53.75%), Query Frame = 1
Query: 682 LSFVILVDCEEDTC-QQALVQRPPIEGWTDHTPSAIGRRIANYKAYTLPVCKYFDDQQKLKMIDGDKTREEVLHDIGKIF 918
FV+ DC ED C ++ L + G TD ++ +RI+ Y +LP+ K+F+ ++K ID EEV ++ KIF
Sbjct: 169 FQFVLFFDCGEDVCVKRCLGRGQSGSGRTDDNLDSLKKRISTYNNDSLPIIKFFEGAGQVKRIDASPDAEEVFGEVEKIF 248 HSP 3 Score: 36.1946 bits (82), Expect = 1.268e-11 Identity = 23/102 (22.55%), Postives = 49/102 (48.04%), Query Frame = 2
Query: 362 LVIFIAGPGMDKKGLANILTKNYPRFYHVELGRLLREKAETEISKGISKWKVAASLMHCGELAPNDMVLETLIKELNYHTDVSGYIIEGYPRNLEQMQDFEK 667
+V + GPG K + + + +F H+ G LLRE+ E G + + G++ P ++ +L++ + S ++I+G+PRN + + + +
Sbjct: 65 IVFVLGGPGAGKGTQCSRIVDRF-QFTHLSAGDLLREERSRE---GSEFGNLIEDYIRNGKIVPVEVTC-SLLENAMKASGKSRFLIDGFPRNQDNLDGWNR 161
BLAST of Adenylate kinase isoenzyme 5 vs. Ensembl Fly
Match: CG9541 (gene:FBgn0032083 transcript:FBtr0332206) HSP 1 Score: 56.9954 bits (136), Expect = 2.758e-13 Identity = 34/104 (32.69%), Postives = 57/104 (54.81%), Query Frame = 2
Query: 362 LVIFIAGPGMDKKGLANILTKNYPRFYHVELGRLLREKAETEISKGISKWKVAASLMHCGELAPN---DMVLETLIKELNYHTDVSGYIIEGYPRNLEQMQDFE 664
++ I GPG +K L P + H+ +GRLLR ++ + V +L G++AP + +LET +++L D +G I++GYPRNL+Q++ FE
Sbjct: 329 IIWVIGGPGSNKATLCLKAVGLNPGWAHISVGRLLRNITDSAPRANTESFAVKEALA-AGDMAPEKSLNQLLETNLRQLR---DRTGIIVDGYPRNLQQVKYFE 428 HSP 2 Score: 38.1206 bits (87), Expect = 2.758e-13 Identity = 21/72 (29.17%), Postives = 34/72 (47.22%), Query Frame = 1
Query: 739 QRPPI-----------EGWTDHTPSAIGRRIANYKAYTLPVCKYFDDQQKLKMIDGDKTREEVLHDIGKIFK 921
QRPPI G D T S+ RR+ ++ TLP+ K D +L+++DGD V + ++ +
Sbjct: 433 QRPPIILLDCSKLQLGRGRIDDTVSSFRRRLELFREQTLPMLKILDTSNRLQIVDGDTDSPSVQREFERLIR 504 HSP 3 Score: 68.5514 bits (166), Expect = 1.241e-11 Identity = 52/187 (27.81%), Postives = 89/187 (47.59%), Query Frame = 1
Query: 1066 SDLPQCPIVILLGGPGCGKTTAATEICTRYKDWVHINVNDIIRYRIFDKGVESTNWDCLAKLSLLNDVHLDQNQLVIEHWNINVEFIKEELKTLKSSTQGIILEGFPKDKVQLQQFNIEIGRADLVILLDCDEYYMTTRLLERGERLHRADDDLSNIKKRIIYYKTSGLPVCRYYDERHILNIIPGD 1626
SDLP PI+ ++GGPG K T + W HI+V ++R I D + K +L + L + ++ L+ L+ T GII++G+P++ Q++ F + + +ILLDC + L RG R DD +S+ ++R+ ++ LP+ + D + L I+ GD
Sbjct: 324 SDLP--PIIWVIGGPGSNKATLCLKAVGLNPGWAHISVGRLLR-NITDSAPRANTESFAVKEALAAGDMAPEKSL--------NQLLETNLRQLRDRT-GIIVDGYPRNLQQVKYFENKYKQRPPIILLDCSKLQ-----LGRG----RIDDTVSSFRRRLELFREQTLPMLKILDTSNRLQIVDGD 489 HSP 4 Score: 50.8322 bits (120), Expect = 3.476e-6 Identity = 48/208 (23.08%), Postives = 94/208 (45.19%), Query Frame = 1
Query: 1069 DLPQCPIVILLGGPGCGKTTAATEICTRYKDWVHINVNDIIRYRIFDKGVESTNWDCLAKLSLLNDVHLDQNQLVIEHWNINVEFIKEELKTLKSSTQGIILEGFPKDKVQLQQFNIEIGRADLVILLDCDEYYMTTRLLERGERLHRADDDLSNIKKRIIYYKTSGLPVCRYYDERHILNIIPGDRKIAEV-------LADVISLLE 1671
D P+ P++ +LGGPG GK T + HIN+ D L + ++ ND+ D +QL + E + E+K + + + ++ G+P+ + +++ +I + VIL+ + + + ++ G +L LS K + + + +PV Y+D+ +L + G+R EV + D++S LE
Sbjct: 64 DPPKVPVIFVLGGPGSGKVTHCDTFMQERRGVTHINM-----------------MDLLQQYAMGNDMQ-DFSQLSSKTV---TEVLMLEMK-MAPAAKAYLISGYPRSMRDVVEYSEKIQVVNGVILISWRQSVL-QKQIDYGAKLGHV--VLSLAKMELENFFKNVMPVADYFDQSDMLLAVNGERAPTEVYKDFRTAVLDILSTLE 246
BLAST of Adenylate kinase isoenzyme 5 vs. Ensembl Fly
Match: CG9541 (gene:FBgn0032083 transcript:FBtr0332207) HSP 1 Score: 56.9954 bits (136), Expect = 3.295e-13 Identity = 34/104 (32.69%), Postives = 57/104 (54.81%), Query Frame = 2
Query: 362 LVIFIAGPGMDKKGLANILTKNYPRFYHVELGRLLREKAETEISKGISKWKVAASLMHCGELAPN---DMVLETLIKELNYHTDVSGYIIEGYPRNLEQMQDFE 664
++ I GPG +K L P + H+ +GRLLR ++ + V +L G++AP + +LET +++L D +G I++GYPRNL+Q++ FE
Sbjct: 359 IIWVIGGPGSNKATLCLKAVGLNPGWAHISVGRLLRNITDSAPRANTESFAVKEALA-AGDMAPEKSLNQLLETNLRQLR---DRTGIIVDGYPRNLQQVKYFE 458 HSP 2 Score: 38.1206 bits (87), Expect = 3.295e-13 Identity = 21/72 (29.17%), Postives = 34/72 (47.22%), Query Frame = 1
Query: 739 QRPPI-----------EGWTDHTPSAIGRRIANYKAYTLPVCKYFDDQQKLKMIDGDKTREEVLHDIGKIFK 921
QRPPI G D T S+ RR+ ++ TLP+ K D +L+++DGD V + ++ +
Sbjct: 463 QRPPIILLDCSKLQLGRGRIDDTVSSFRRRLELFREQTLPMLKILDTSNRLQIVDGDTDSPSVQREFERLIR 534 HSP 3 Score: 68.1662 bits (165), Expect = 1.503e-11 Identity = 52/187 (27.81%), Postives = 89/187 (47.59%), Query Frame = 1
Query: 1066 SDLPQCPIVILLGGPGCGKTTAATEICTRYKDWVHINVNDIIRYRIFDKGVESTNWDCLAKLSLLNDVHLDQNQLVIEHWNINVEFIKEELKTLKSSTQGIILEGFPKDKVQLQQFNIEIGRADLVILLDCDEYYMTTRLLERGERLHRADDDLSNIKKRIIYYKTSGLPVCRYYDERHILNIIPGD 1626
SDLP PI+ ++GGPG K T + W HI+V ++R I D + K +L + L + ++ L+ L+ T GII++G+P++ Q++ F + + +ILLDC + L RG R DD +S+ ++R+ ++ LP+ + D + L I+ GD
Sbjct: 354 SDLP--PIIWVIGGPGSNKATLCLKAVGLNPGWAHISVGRLLR-NITDSAPRANTESFAVKEALAAGDMAPEKSL--------NQLLETNLRQLRDRT-GIIVDGYPRNLQQVKYFENKYKQRPPIILLDCSKLQ-----LGRG----RIDDTVSSFRRRLELFREQTLPMLKILDTSNRLQIVDGD 519 HSP 4 Score: 50.8322 bits (120), Expect = 4.437e-6 Identity = 48/208 (23.08%), Postives = 94/208 (45.19%), Query Frame = 1
Query: 1069 DLPQCPIVILLGGPGCGKTTAATEICTRYKDWVHINVNDIIRYRIFDKGVESTNWDCLAKLSLLNDVHLDQNQLVIEHWNINVEFIKEELKTLKSSTQGIILEGFPKDKVQLQQFNIEIGRADLVILLDCDEYYMTTRLLERGERLHRADDDLSNIKKRIIYYKTSGLPVCRYYDERHILNIIPGDRKIAEV-------LADVISLLE 1671
D P+ P++ +LGGPG GK T + HIN+ D L + ++ ND+ D +QL + E + E+K + + + ++ G+P+ + +++ +I + VIL+ + + + ++ G +L LS K + + + +PV Y+D+ +L + G+R EV + D++S LE
Sbjct: 64 DPPKVPVIFVLGGPGSGKVTHCDTFMQERRGVTHINM-----------------MDLLQQYAMGNDMQ-DFSQLSSKTV---TEVLMLEMK-MAPAAKAYLISGYPRSMRDVVEYSEKIQVVNGVILISWRQSVL-QKQIDYGAKLGHV--VLSLAKMELENFFKNVMPVADYFDQSDMLLAVNGERAPTEVYKDFRTAVLDILSTLE 246
BLAST of Adenylate kinase isoenzyme 5 vs. Ensembl Zebrafish
Match: ak5 (adenylate kinase 5 [Source:ZFIN;Acc:ZDB-GENE-030131-8256]) HSP 1 Score: 111.309 bits (277), Expect = 3.490e-43 Identity = 76/238 (31.93%), Postives = 121/238 (50.84%), Query Frame = 2
Query: 83 NAKDYLAKNEIPQLFECLMTGLMYHRPLSHIDYLQQCLDRIKK-QGVNGVRWDMFL--EAKSIP-----------------------------LPPISPSCKEEFTAEGVTD-SNTIQLNISYDV--------ALVIFIAGPGMDKKGLANILTKNYPRFYHVELGRLLREKAETEISKGISKWKVAASLMHCGELAPNDMVLETLIKELNYHTDVSGYIIEGYPRNLEQMQDFEKFV 673
+AK+YL++ EIPQLFE L+TGLMY+RP ++YL+ CL +++ G + VRWD F+ E KS+P LPPI+ +F+ E +D S T +L Y+V +++ I GPG K + + Y F +V +G LLR+K + KW + A ++ GELAP + + + +++ + SG +I+G+PR++ Q FE V
Sbjct: 5 DAKEYLSRREIPQLFESLLTGLMYYRPDDPLEYLETCLKKVRDLGGTDKVRWDTFVGQEKKSLPPLNGGQSRRSFFRNVLPDSPNFPYRRYERLPPIN-----QFSIESDSDLSETAELIEEYEVFDPSRPRPKVILIIGGPGSGKGTQCLKIAERY-GFEYVSVGELLRKKMIHNATSN-RKWSLIARIITNGELAPQETTITEIKQKIMKIPEASGIVIDGFPRDVGQALSFEDQV 235 HSP 2 Score: 85.1149 bits (209), Expect = 3.490e-43 Identity = 76/336 (22.62%), Postives = 151/336 (44.94%), Query Frame = 1
Query: 688 FVILVDCEEDTCQQALVQRPPIEGWTDHTPSAIGRRIANYKAYTLPVCKYFDDQQKLKMIDGDKTREEVLHDIG-----KIFKXXXXXXXXXXXXXXXXXXXXYNEIPPPGVAQVQDIEEIFNIDPEIIR--PSDLPQCPIVILLGGPGCGKTTAATEICTRYKDWVHINVNDIIRYRIFDKGVESTNWDCLAKLSLLNDVHLDQNQLVIEHWNINVEFIKEELKTLKSSTQGIILEGFPKDKVQLQQFNIEIGRADLVILLDCDEYYMTTRLLERGE-RLHRADDDLSNIKKRIIYYKTSGLPVCRYYDERHILNIIPGDRKIAEVLADVISLLE 1671
V+ + C ++ L +R +G D P AI RR+ N+K +P+ KYF ++ + +D D+ EEV +DI K+F + E+ + P + D EE+ I P + + ++ ++GGPG GK + +I RY + DI+ + + L D+ L++ + + E + ++ + E + + +G ++ GFPK++ Q Q++ ++G+ D+V+LL+C M+ RL +R LH + + ++R+ + + PV +Y R + I ++ +V + +L+
Sbjct: 240 LVVFLACSNQRLKERLEKRAEQQGRPDDNPKAIDRRLTNFKQNAIPLVKYFQEKGLIVTLDADRDEEEVFYDISMTVDNKLFPTKEPVAGPSELDLSLIADSSSLTDVPAKFDEQAD-EEVAEYAEAIGESFPMETKKSKVIFVIGGPGSGKALQSEKIEERY-SLKRLCPGDILCSELQSHS---------ERGRFLRDL-LERGEQLPE--DTLLDLLCEAMASTVRQGKGFLVTGFPKNEKQAQEYEAKMGQPDIVLLLECSADIMSRRLQQRATCSLHSKEARDRDTRRRVDGFCSLINPVVAHYQHREFFHKIDAEQPPEDVFEHICVVLD 561 HSP 3 Score: 98.5969 bits (244), Expect = 4.686e-21 Identity = 57/211 (27.01%), Postives = 108/211 (51.18%), Query Frame = 1
Query: 1024 IEEIFNIDPEIIRPSDLPQCPIVILLGGPGCGKTTAATEICTRYKDWVHINVNDIIRYRIFDKGVESTNWDCLAKLSLLNDVHLDQNQLVIEHWNINVEFIKEELKTLKSSTQGIILEGFPKDKVQLQQFNIEIGRADLVILLDCDEYYMTTRLLERGERLHRADDDLSNIKKRIIYYKTSGLPVCRYYDERHILNIIPGDRKIAEVLADV 1656
IEE DP RP +++++GGPG GK T +I RY + +++V +++R ++ + W +A++ + N Q + E IK+++ + ++ GI+++GFP+D Q F ++ DLV+ L C + RL +R E+ R DD+ I +R+ +K + +P+ +Y+ E+ ++ + DR EV D+
Sbjct: 119 IEEYEVFDPSRPRPK------VILIIGGPGSGKGTQCLKIAERY-GFEYVSVGELLRKKMIHNATSNRKWSLIARI-ITNGELAPQETTITE--------IKQKIMKIPEAS-GIVIDGFPRDVGQALSFEDQVCTPDLVVFLACSNQRLKERLEKRAEQQGRPDDNPKAIDRRLTNFKQNAIPLVKYFQEKGLIVTLDADRDEEEVFYDI 312
BLAST of Adenylate kinase isoenzyme 5 vs. Ensembl Zebrafish
Match: ak5l (adenylate kinase 5, like [Source:ZFIN;Acc:ZDB-GENE-050410-2]) HSP 1 Score: 111.694 bits (278), Expect = 7.203e-30 Identity = 72/233 (30.90%), Postives = 112/233 (48.07%), Query Frame = 2
Query: 83 NAKDYLAKNEIPQLFECLMTGLMYHRPLSHIDYLQQCLDRIKK-QGVNGVRWDMFLEAKSIPLPPISPS------CK----------------------EEFTAEGVTD-SNTIQLNISYDV--------ALVIFIAGPGMDKKGLANILTKNYPRFYHVELGRLLREKAETEISKGISKWKVAASLMHCGELAPNDMVLETLIKELNYHTDVSGYIIEGYPRNLEQMQDFEK 667
+AKDYL+K +IP LFE ++TGLMYH+P + +L+ CL + + G V WD F+ PLPPI+P+ CK +F+ E +D + + L YDV ++ I GPG K + Y F HV +G +LR + + KW++ A ++ GELAP + +E L ++ D G+I++G+PR + Q FE+
Sbjct: 5 DAKDYLSKRQIPHLFESMLTGLMYHKPEDPLAFLEICLQKTRDLGGPECVVWDTFITPDRKPLPPITPAQGKKAPCKLDGGPGPGPGPYRRYDRLPPIQAQFSIESDSDMTESSGLIQEYDVFDPSKPRPHIIFIIGGPGSGKGTQTAKIALRY-DFEHVSVGEILRNQL-LHHAPSDRKWELIAQIIANGELAPQETTIEELKQQFIKKQDAKGFIVDGFPREISQAFTFEE 235 HSP 2 Score: 39.6614 bits (91), Expect = 7.203e-30 Identity = 21/78 (26.92%), Postives = 38/78 (48.72%), Query Frame = 1
Query: 688 FVILVDCEEDTCQQALVQRPPIEGWTDHTPSAIGRRIANYKAYTLPVCKYFDDQQKLKMIDGDKTREEVLHDIGKIFK 921
VIL+ C +Q L +R +G D AI +R+ +K + KY+ ++ + +D D+ +++ DI I K
Sbjct: 242 LVILLACSNQQLRQRLEKRASQQGRPDDNSHAIEKRLDTFKHNINLIAKYYQERGLIVRVDADREEDDIFTDISAIVK 319 HSP 3 Score: 103.605 bits (257), Expect = 1.447e-23 Identity = 64/216 (29.63%), Postives = 112/216 (51.85%), Query Frame = 1
Query: 1024 IEEIFNIDPEIIRPSDLPQCPIVILLGGPGCGKTTAATEICTRYKDWVHINVNDIIRYRIFDKGVESTNWDCLAKLSLLNDVHLDQNQLVIEHWNINVEFIKEELKTLKSSTQGIILEGFPKDKVQLQQFNIEIGRADLVILLDCDEYYMTTRLLERGERLHRADDDLSNIKKRIIYYKTSGLPVCRYYDERHILNIIPGDRKIAEVLADVISLLE 1671
I+E DP RP I+ ++GGPG GK T +I RY D+ H++V +I+R ++ W+ +A++ + + L + IE + +FIK K +G I++GFP++ Q F +IG DLVILL C + RL +R + R DD+ I+KR+ +K + + +YY ER ++ + DR+ ++ D+ ++++
Sbjct: 121 IQEYDVFDPSKPRPH------IIFIIGGPGSGKGTQTAKIALRY-DFEHVSVGEILRNQLLHHAPSDRKWELIAQI--IANGELAPQETTIEE--LKQQFIK------KQDAKGFIVDGFPREISQAFTFEEQIGSPDLVILLACSNQQLRQRLEKRASQQGRPDDNSHAIEKRLDTFKHNINLIAKYYQERGLIVRVDADREEDDIFTDISAIVK 319
BLAST of Adenylate kinase isoenzyme 5 vs. Ensembl Zebrafish
Match: cmpk (cytidylate kinase [Source:NCBI gene;Acc:406383]) HSP 1 Score: 88.9669 bits (219), Expect = 1.742e-19 Identity = 63/204 (30.88%), Postives = 106/204 (51.96%), Query Frame = 1
Query: 1075 PQCPIVILLGGPGCGKTTAATEICTRYKDWVHINVNDIIRYRIFDKGVESTNWDCLAKLSLLNDVHLDQNQLVIEHWNINVEFIKEELKTLKSSTQGI--ILEGFPKDKVQLQQFNIEI-GRAD--LVILLDCDEYYMTTRLLERGERLHRADDDLSNIKKRIIYYKTSGLPVCRYYDERHILNIIPGDRKIAEVLADVISLLE 1671
PQ +V +LGGPG GK T I Y + H++ D++R E + D ++ L D ++ + ++V IN+ K +T+K+ + +++GFP+++ LQ +N E+ G+AD V+ DC R LERG+ R DD+ +++KRI Y S P+ Y+++ + I R + EV ADV ++LE
Sbjct: 28 PQ--VVFVLGGPGAGKGTQCARIVENY-SYTHLSAGDLLRE-------ERSRTD--SEFGQLIDSYIKEGKIVPVQITINL-LRKAMEETMKADEKKFRFLIDGFPRNQDNLQGWNTEMDGKADVKFVLFFDCSNEVCIDRCLERGKSSGRTDDNRESLEKRIQTYLQSTRPIIELYEKQGKVQRIDASRSVDEVFADVKNILE 218 HSP 2 Score: 49.2914 bits (116), Expect = 3.652e-10 Identity = 22/80 (27.50%), Postives = 41/80 (51.25%), Query Frame = 1
Query: 682 LSFVILVDCEEDTCQQALVQRPPIEGWTDHTPSAIGRRIANYKAYTLPVCKYFDDQQKLKMIDGDKTREEVLHDIGKIFK 921
+ FV+ DC + C ++R G TD ++ +RI Y T P+ + ++ Q K++ ID ++ +EV D+ I +
Sbjct: 139 VKFVLFFDCSNEVCIDRCLERGKSSGRTDDNRESLEKRIQTYLQSTRPIIELYEKQGKVQRIDASRSVDEVFADVKNILE 218 HSP 3 Score: 35.8094 bits (81), Expect = 3.652e-10 Identity = 27/103 (26.21%), Postives = 50/103 (48.54%), Query Frame = 2
Query: 362 LVIFIAGPGMDKKGLANILTKNYPRFYHVELGRLLREKAETEISKGISKW-KVAASLMHCGELAPNDMVLETLIKELNYHTDVS----GYIIEGYPRNLEQMQ 655
+V + GPG K + +NY + H+ G LLRE E S+ S++ ++ S + G++ P + + L K + ++I+G+PRN + +Q
Sbjct: 30 VVFVLGGPGAGKGTQCARIVENYS-YTHLSAGDLLRE----ERSRTDSEFGQLIDSYIKEGKIVPVQITINLLRKAMEETMKADEKKFRFLIDGFPRNQDNLQ 127
BLAST of Adenylate kinase isoenzyme 5 vs. Ensembl Zebrafish
Match: cmpk (cytidylate kinase [Source:NCBI gene;Acc:406383]) HSP 1 Score: 88.5817 bits (218), Expect = 1.888e-19 Identity = 63/204 (30.88%), Postives = 106/204 (51.96%), Query Frame = 1
Query: 1075 PQCPIVILLGGPGCGKTTAATEICTRYKDWVHINVNDIIRYRIFDKGVESTNWDCLAKLSLLNDVHLDQNQLVIEHWNINVEFIKEELKTLKSSTQGI--ILEGFPKDKVQLQQFNIEI-GRAD--LVILLDCDEYYMTTRLLERGERLHRADDDLSNIKKRIIYYKTSGLPVCRYYDERHILNIIPGDRKIAEVLADVISLLE 1671
PQ +V +LGGPG GK T I Y + H++ D++R E + D ++ L D ++ + ++V IN+ K +T+K+ + +++GFP+++ LQ +N E+ G+AD V+ DC R LERG+ R DD+ +++KRI Y S P+ Y+++ + I R + EV ADV ++LE
Sbjct: 26 PQ--VVFVLGGPGAGKGTQCARIVENY-SYTHLSAGDLLRE-------ERSRTD--SEFGQLIDSYIKEGKIVPVQITINL-LRKAMEETMKADEKKFRFLIDGFPRNQDNLQGWNTEMDGKADVKFVLFFDCSNEVCIDRCLERGKSSGRTDDNRESLEKRIQTYLQSTRPIIELYEKQGKVQRIDASRSVDEVFADVKNILE 216 HSP 2 Score: 49.2914 bits (116), Expect = 3.537e-10 Identity = 22/80 (27.50%), Postives = 41/80 (51.25%), Query Frame = 1
Query: 682 LSFVILVDCEEDTCQQALVQRPPIEGWTDHTPSAIGRRIANYKAYTLPVCKYFDDQQKLKMIDGDKTREEVLHDIGKIFK 921
+ FV+ DC + C ++R G TD ++ +RI Y T P+ + ++ Q K++ ID ++ +EV D+ I +
Sbjct: 137 VKFVLFFDCSNEVCIDRCLERGKSSGRTDDNRESLEKRIQTYLQSTRPIIELYEKQGKVQRIDASRSVDEVFADVKNILE 216 HSP 3 Score: 35.8094 bits (81), Expect = 3.537e-10 Identity = 27/103 (26.21%), Postives = 50/103 (48.54%), Query Frame = 2
Query: 362 LVIFIAGPGMDKKGLANILTKNYPRFYHVELGRLLREKAETEISKGISKW-KVAASLMHCGELAPNDMVLETLIKELNYHTDVS----GYIIEGYPRNLEQMQ 655
+V + GPG K + +NY + H+ G LLRE E S+ S++ ++ S + G++ P + + L K + ++I+G+PRN + +Q
Sbjct: 28 VVFVLGGPGAGKGTQCARIVENYS-YTHLSAGDLLRE----ERSRTDSEFGQLIDSYIKEGKIVPVQITINLLRKAMEETMKADEKKFRFLIDGFPRNQDNLQ 125
BLAST of Adenylate kinase isoenzyme 5 vs. Ensembl Zebrafish
Match: cmpk (cytidylate kinase [Source:NCBI gene;Acc:406383]) HSP 1 Score: 88.5817 bits (218), Expect = 1.954e-19 Identity = 61/200 (30.50%), Postives = 104/200 (52.00%), Query Frame = 1
Query: 1087 IVILLGGPGCGKTTAATEICTRYKDWVHINVNDIIRYRIFDKGVESTNWDCLAKLSLLNDVHLDQNQLVIEHWNINVEFIKEELKTLKSSTQGI--ILEGFPKDKVQLQQFNIEI-GRAD--LVILLDCDEYYMTTRLLERGERLHRADDDLSNIKKRIIYYKTSGLPVCRYYDERHILNIIPGDRKIAEVLADVISLLE 1671
+V +LGGPG GK T I Y + H++ D++R E + D ++ L D ++ + ++V IN+ K +T+K+ + +++GFP+++ LQ +N E+ G+AD V+ DC R LERG+ R DD+ +++KRI Y S P+ Y+++ + I R + EV ADV ++LE
Sbjct: 34 VVFVLGGPGAGKGTQCARIVENY-SYTHLSAGDLLRE-------ERSRTD--SEFGQLIDSYIKEGKIVPVQITINL-LRKAMEETMKADEKKFRFLIDGFPRNQDNLQGWNTEMDGKADVKFVLFFDCSNEVCIDRCLERGKSSGRTDDNRESLEKRIQTYLQSTRPIIELYEKQGKVQRIDASRSVDEVFADVKNILE 222 HSP 2 Score: 49.2914 bits (116), Expect = 3.178e-10 Identity = 22/80 (27.50%), Postives = 41/80 (51.25%), Query Frame = 1
Query: 682 LSFVILVDCEEDTCQQALVQRPPIEGWTDHTPSAIGRRIANYKAYTLPVCKYFDDQQKLKMIDGDKTREEVLHDIGKIFK 921
+ FV+ DC + C ++R G TD ++ +RI Y T P+ + ++ Q K++ ID ++ +EV D+ I +
Sbjct: 143 VKFVLFFDCSNEVCIDRCLERGKSSGRTDDNRESLEKRIQTYLQSTRPIIELYEKQGKVQRIDASRSVDEVFADVKNILE 222 HSP 3 Score: 36.1946 bits (82), Expect = 3.178e-10 Identity = 27/103 (26.21%), Postives = 50/103 (48.54%), Query Frame = 2
Query: 362 LVIFIAGPGMDKKGLANILTKNYPRFYHVELGRLLREKAETEISKGISKW-KVAASLMHCGELAPNDMVLETLIKELNYHTDVS----GYIIEGYPRNLEQMQ 655
+V + GPG K + +NY + H+ G LLRE E S+ S++ ++ S + G++ P + + L K + ++I+G+PRN + +Q
Sbjct: 34 VVFVLGGPGAGKGTQCARIVENYS-YTHLSAGDLLRE----ERSRTDSEFGQLIDSYIKEGKIVPVQITINLLRKAMEETMKADEKKFRFLIDGFPRNQDNLQ 131
BLAST of Adenylate kinase isoenzyme 5 vs. Ensembl Xenopus
Match: ak5 (adenylate kinase 5 [Source:NCBI gene;Acc:100127649]) HSP 1 Score: 113.235 bits (282), Expect = 1.927e-47 Identity = 74/233 (31.76%), Postives = 115/233 (49.36%), Query Frame = 2
Query: 74 TPRNAKDYLAKNEIPQLFECLMTGLMYHRPLSHIDYLQQCLDRIKK-QGVNGVRWDMFLEAKSIPLPPISPSCKE--------------------------EFTAEGVTD-SNTIQLNISYDV--------ALVIFIAGPGMDKKGLANILTKNYPRFYHVELGRLLREKAETEISKGISKWKVAASLMHCGELAPNDMVLETLIKELNYHTDVSGYIIEGYPRNLEQMQDFE 664
T + K+YLA+ EIPQLFE L+ GLMY+RP +DYL+ CL ++K+ G VRWD F+ LPP++ +F+ E TD S T +L Y+V +++ I GPG K + + + Y F ++ +G LLR+K + S KW + A ++ GELAP + + + ++L D G +I+G+PR++ Q FE
Sbjct: 2 TSGDPKEYLARREIPQLFEGLLNGLMYYRPDDPVDYLENCLQKVKELGGTEKVRWDTFVGPDKRNLPPLNGGQARRSFFRNVMPDGGNFPYRRYDRLPPIHQFSIESDTDLSETAELIEEYEVFDPSRPHPKIILVIGGPGSGKGTQSLKIAERYG-FEYISVGELLRKKIHSTSSN--RKWSLIAKIITTGELAPQETTITEIKQKLMQIPDSEGIVIDGFPRDVAQALSFE 231 HSP 2 Score: 97.8265 bits (242), Expect = 1.927e-47 Identity = 83/347 (23.92%), Postives = 160/347 (46.11%), Query Frame = 1
Query: 664 EICMNRLSFVILVDCEEDTCQQALVQRPPIEGWTDHTPSAIGRRIANYKAYTLPVCKYFDDQQKLKMIDGDKTREEVLHDIG-----KIFKXXXXXXXXXXXXXXXXXXXXYNEIPPPGVAQVQDIEEIF-NIDPEIIRP----SDLPQCPIVILL-GGPGCGKTTAATEICTRYKDWVHINVNDIIRYRIFDKGVESTNWDCLAKLSLLNDVHLDQNQLVIEHWNINVEFIKEELKTLKSSTQGIILEGFPKDKVQLQQFNIEIGRADLVILLDCDEYYMTTRLLERGERLHRADDDLSNIKKRIIYYKTSGLPVCRYYDERHILNIIPGDRKIAEVLADVISLLE 1671
+IC L V+ + C ++ L +R +G D AI RR+ N+K +P+ YF ++ + D D+ EEV DI K+F + E E+ + D+E F + E+++P L C + + GGPG GK T ++ RY + V++++ +S + L+ D+ +Q+ + +I +E +KE + + +++G + +GFP++ Q ++F +I + ++V+ LDC MT+RL +R + HR D + I++R+ Y + P+ YY+ + +L I ++ +V + S ++
Sbjct: 233 QICTPDL--VVFLACASHKLKERLQKRAEQQGRPDDNLKAIQRRLMNFKQNAVPLVNYFQEKGLIITFDADREEEEVFCDISAAVDNKLFPAKTPVAEPSELDLSLIIDS----------GDTCDLELNFEDQRHELMQPFGDDCRLRVCNFFLCIKGGPGSGKGTQCEKLAHRY-GLSPLAVSELL---------QSDLATFTERSKLIKDIMEHGDQVPM---DIILEIVKETMSSCLGNSKGFLFDGFPRETKQAEEFECKISKPNIVLYLDCSAETMTSRLQKRSKASHRNDINTETIRRRLEAYYQAINPIITYYERKSLLYKINAEKSPEDVFLHICSAVD 554 HSP 3 Score: 103.219 bits (256), Expect = 2.202e-22 Identity = 61/207 (29.47%), Postives = 113/207 (54.59%), Query Frame = 1
Query: 1051 EIIRPSDLPQCPIVILLGGPGCGKTTAATEICTRYKDWVHINVNDIIRYRIFDKGVESTNWDCLAKLSLLNDVHLDQNQLVIEHWNINVEFIKEELKTLKSSTQGIILEGFPKDKVQLQQFNIEIGRADLVILLDCDEYYMTTRLLERGERLHRADDDLSNIKKRIIYYKTSGLPVCRYYDERHILNIIPGDRKIAEVLADVISLLE 1671
E+ PS P I++++GGPG GK T + +I RY + +I+V +++R +I + W +AK+ + +L + I IK++L + S +GI+++GFP+D Q F +I DLV+ L C + + RL +R E+ R DD+L I++R++ +K + +P+ Y+ E+ ++ DR+ EV D+ + ++
Sbjct: 123 EVFDPSR-PHPKIILVIGGPGSGKGTQSLKIAERY-GFEYISVGELLRKKIHSTS-SNRKWSLIAKI-------ITTGELAPQETTITE--IKQKLMQIPDS-EGIVIDGFPRDVAQALSFEDQICTPDLVVFLACASHKLKERLQKRAEQQGRPDDNLKAIQRRLMNFKQNAVPLVNYFQEKGLIITFDADREEEEVFCDISAAVD 316
BLAST of Adenylate kinase isoenzyme 5 vs. Ensembl Xenopus
Match: ak5 (adenylate kinase 5 [Source:NCBI gene;Acc:100127649]) HSP 1 Score: 104.76 bits (260), Expect = 1.524e-34 Identity = 82/361 (22.71%), Postives = 162/361 (44.88%), Query Frame = 1
Query: 664 EICMNRLSFVILVDCEEDTCQQALVQRPPIEGWTDHTPSAIGRRIANYKAYTLPVCKYFDDQQKLKMIDGDKTREEVLHDIGKIFKXXXXXXXXXXXXXXXXXXXXYNEIPPPG--VAQVQDIEEIFNIDP---------------EIIRP--------SDLPQCPIVILLGGPGCGKTTAATEICTRYKDWVHINVNDIIRYRIFDKGVESTNWDCLAKLSLLNDVHLDQNQLVIEHWNINVEFIKEELKTLKSSTQGIILEGFPKDKVQLQQFNIEIGRADLVILLDCDEYYMTTRLLERGERLHRADDDLSNIKKRIIYYKTSGLPVCRYYDERHILNIIPGDRKIAEVLADVISLLE 1671
+IC L V+ + C ++ L +R +G D AI RR+ N+K +P+ YF ++ + D D+ EEV DI N++ P VA+ +++ ID E+++P +L + ++ +LGGPG GK T ++ RY + V++++ +S + L+ D+ +Q+ + +I +E +KE + + +++G + +GFP++ Q ++F +I + ++V+ LDC MT+RL +R + HR D + I++R+ Y + P+ YY+ + +L I ++ +V + S ++
Sbjct: 150 QICTPDL--VVFLACASHKLKERLQKRAEQQGRPDDNLKAIQRRLMNFKQNAVPLVNYFQEKGLIITFDADREEEEVFCDISAAVD---------------------NKLFPAKTPVAEPSELDLSLIIDSGDTCDLELNFEDQRHELMQPFGDDCRLREELKKAKVIFVLGGPGSGKGTQCEKLAHRY-GLSPLAVSELL---------QSDLATFTERSKLIKDIMEHGDQVPM---DIILEIVKETMSSCLGNSKGFLFDGFPRETKQAEEFECKISKPNIVLYLDCSAETMTSRLQKRSKASHRNDINTETIRRRLEAYYQAINPIITYYERKSLLYKINAEKSPEDVFLHICSAVD 474 HSP 2 Score: 63.1586 bits (152), Expect = 1.524e-34 Identity = 44/142 (30.99%), Postives = 72/142 (50.70%), Query Frame = 2
Query: 266 LPPISPSCKEEFTAEGVTD-SNTIQLNISYDV--------ALVIFIAGPGMDKKGLANILTKNYPRFYHVELGRLLREKAETEISKGISKWKVAASLMHCGELAPNDMVLETLIKELNYHTDVSGYIIEGYPRNLEQMQDFE 664
LPPI +F+ E TD S T +L Y+V +++ I GPG K + + + Y F ++ +G LLR+K + S KW + A ++ GELAP + + + ++L D G +I+G+PR++ Q FE
Sbjct: 15 LPPI-----HQFSIESDTDLSETAELIEEYEVFDPSRPHPKIILVIGGPGSGKGTQSLKIAERYG-FEYISVGELLRKKIHSTSSN--RKWSLIAKIITTGELAPQETTITEIKQKLMQIPDSEGIVIDGFPRDVAQALSFE 148 HSP 3 Score: 103.605 bits (257), Expect = 9.223e-23 Identity = 61/207 (29.47%), Postives = 113/207 (54.59%), Query Frame = 1
Query: 1051 EIIRPSDLPQCPIVILLGGPGCGKTTAATEICTRYKDWVHINVNDIIRYRIFDKGVESTNWDCLAKLSLLNDVHLDQNQLVIEHWNINVEFIKEELKTLKSSTQGIILEGFPKDKVQLQQFNIEIGRADLVILLDCDEYYMTTRLLERGERLHRADDDLSNIKKRIIYYKTSGLPVCRYYDERHILNIIPGDRKIAEVLADVISLLE 1671
E+ PS P I++++GGPG GK T + +I RY + +I+V +++R +I + W +AK+ + +L + I IK++L + S +GI+++GFP+D Q F +I DLV+ L C + + RL +R E+ R DD+L I++R++ +K + +P+ Y+ E+ ++ DR+ EV D+ + ++
Sbjct: 40 EVFDPSR-PHPKIILVIGGPGSGKGTQSLKIAERY-GFEYISVGELLRKKIHSTS-SNRKWSLIAKI-------ITTGELAPQETTITE--IKQKLMQIPDS-EGIVIDGFPRDVAQALSFEDQICTPDLVVFLACASHKLKERLQKRAEQQGRPDDNLKAIQRRLMNFKQNAVPLVNYFQEKGLIITFDADREEEEVFCDISAAVD 233
BLAST of Adenylate kinase isoenzyme 5 vs. Ensembl Xenopus
Match: ak1 (adenylate kinase 1 [Source:NCBI gene;Acc:448536]) HSP 1 Score: 107.071 bits (266), Expect = 1.333e-26 Identity = 67/227 (29.52%), Postives = 114/227 (50.22%), Query Frame = 2
Query: 83 NAKDYLAKNEIPQLFECLMTGLMYHRPLSHIDYLQQCLDRIKK-QGVNGVRWDMFL-----------------EAKSIPLPPIS-----PSCKEEFTAEGVTD-SNTIQLNISYDV--------ALVIFIAGPGMDKKGLANILTKNYPRFYHVELGRLLREKAETEISKGISKWKVAASLMHCGELAPNDMVLETLIKELNYHTDVSGYIIEGYPRNLEQMQDFEK 667
AKDYL IP+LFE L+TGLMY+RP I Y++ CL +++ G V+WD FL A+ +P P + P + +F+ + +D + + L YDV ++ I GPG K + + ++ F V +G +LR++ S KW++ A ++ G+LAP + +E L ++ H D +G++++G+PR++ Q FE+
Sbjct: 5 QAKDYLTDRHIPRLFESLLTGLMYYRPEDPISYMEMCLQKVRDIGGPEKVQWDTFLSRNLPPINGGQGKKTPHRAEGLPAPQMRRYERLPPIQSQFSIDSDSDMTESSGLIQEYDVFDPNRERPKIIFVIGGPGSGKGTQSTKMASHF-GFICVSVGDILRKQLIHHASSD-RKWELIAQIISKGDLAPPETTIEELKQQFINHQDATGFVVDGFPRDIGQAFTFEE 229 HSP 2 Score: 34.2686 bits (77), Expect = 1.333e-26 Identity = 20/73 (27.40%), Postives = 34/73 (46.58%), Query Frame = 1
Query: 688 FVILVDCEEDTCQQALVQRPPIEGWTDHTPSAIGRRIANYKAYTLPVCKYFDDQQKLKMIDGDKTREEVLHDI 906
VI + C +Q L +R + G D AI RR++ +K + KY+ D+ + D D+ + + DI
Sbjct: 236 LVIFLACSSQRLRQRLERRASLHGRPDDNAHAIDRRLSTFKQNLPLIVKYYQDKGLIARFDADREEDSIFEDI 308 HSP 3 Score: 81.6481 bits (200), Expect = 6.722e-16 Identity = 55/222 (24.77%), Postives = 106/222 (47.75%), Query Frame = 1
Query: 1024 IEEIFNIDPEIIRPSDLPQCPIVILLGGPGCGKTTAATEICTRYKDWVHINVNDIIRYRIFDKGVESTNWDCLAKLSLLNDVHLDQNQLVIEHWNINVEFIKEELKTLKSSTQGIILEGFPKDKVQLQQFNIEIGRADLVILLDCDEYYMTTRLLERGERLHRADDDLSNIKKRIIYYKTSGLPVCRYYDERHILNIIPGDRKIAEVLADVISLLELAIMKN 1689
I+E DP RP I+ ++GGPG GK T +T++ + + ++ ++V DI+R ++ W+ +A++ D+ + +E +K++ + +T G +++GFP+D Q F +IG DLVI L C + RL R R DD+ I +R+ +K + + +YY ++ ++ DR+ + D+ ++ + N
Sbjct: 115 IQEYDVFDPNRERPK------IIFVIGGPGSGKGTQSTKMASHF-GFICVSVGDILRKQLIHHASSDRKWELIAQIISKGDLAPPET---------TIEELKQQFINHQDAT-GFVVDGFPRDIGQAFTFEEQIGSPDLVIFLACSSQRLRQRLERRASLHGRPDDNAHAIDRRLSTFKQNLPLIVKYYQDKGLIARFDADREEDSIFEDICCAVQGLLFPN 319
BLAST of Adenylate kinase isoenzyme 5 vs. Ensembl Xenopus
Match: ak1 (adenylate kinase 1 [Source:NCBI gene;Acc:448536]) HSP 1 Score: 94.3597 bits (233), Expect = 4.057e-21 Identity = 62/219 (28.31%), Postives = 116/219 (52.97%), Query Frame = 1
Query: 1018 QDIEEIFNIDPEIIRPSD-LPQCPIVILLGGPGCGKTTAATEICTRYKDWVHINVNDIIRYRIFDKGVESTNWDCLAKLSLLNDVHLDQNQLVIEHWNINVEFIKEELKTLKSSTQGIILEGFPKDKVQLQQFNIEIGRADLVILLDCDEYYMTTRLLERGERLHRADDDLSNIKKRIIYYKTSGLPVCRYYDERHILNIIPGDRKIAEVLADVISLLE 1671
Q+IE +F+ PE +D L I+ ++GGPG GK T +I +Y + H++ D++R + S+ + LS + +++ +LV + ++ +KE + +++G +++G+P++ Q ++F +IG L++ +D M RLL+RGE RADD+ + IKKR+ Y + PV Y+ R I+ I + + +V V + L+
Sbjct: 33 QEIEVVFS--PEHTEMADKLKNSKIIFVVGGPGSGKGTQCEKIVHQY-GYTHLSTGDLLRAEV------SSGSERGKHLSAI----MEKGELV--PLDTVLDMLKEAMIAKADTSKGYLIDGYPREVKQGEEFEKKIGPPSLLLYIDAGSDTMVKRLLKRGETSGRADDNEATIKKRLETYYKATEPVIAMYEGRGIVRKINAEGSVDDVFKQVSTALD 236 HSP 2 Score: 63.1586 bits (152), Expect = 2.133e-10 Identity = 36/105 (34.29%), Postives = 57/105 (54.29%), Query Frame = 2
Query: 362 LVIFIAGPGMDKKGLANILTKNYPRFYHVELGRLLREKAETEISKGISKWKVAASLMHCGELAPNDMVLETLIKELNYHTDVS-GYIIEGYPRNLEQMQDFEKFV 673
++ + GPG K + Y + H+ G LLR E+S G + K +++M GEL P D VL+ L + + D S GY+I+GYPR ++Q ++FEK +
Sbjct: 55 IIFVVGGPGSGKGTQCEKIVHQYG-YTHLSTGDLLR----AEVSSGSERGKHLSAIMEKGELVPLDTVLDMLKEAMIAKADTSKGYLIDGYPREVKQGEEFEKKI 154
BLAST of Adenylate kinase isoenzyme 5 vs. Ensembl Xenopus
Match: ak1 (adenylate kinase 1 [Source:NCBI gene;Acc:448536]) HSP 1 Score: 87.0409 bits (214), Expect = 1.038e-20 Identity = 58/212 (27.36%), Postives = 104/212 (49.06%), Query Frame = 2
Query: 128 ECLMTGLMYHRPLSHIDYLQQCLDRIKK-QGVNGVRWDMFL-----------------EAKSIPLPPIS-----PSCKEEFTAEGVTD-SNTIQLNISYDV--------ALVIFIAGPGMDKKGLANILTKNYPRFYHVELGRLLREKAETEISKGISKWKVAASLMHCGELAPNDMVLETLIKELNYHTDVSGYIIEGYPRNLEQMQDFEK 667
+ L+TGLMY+RP I Y++ CL +++ G V+WD FL A+ +P P + P + +F+ + +D + + L YDV ++ I GPG KG + ++ F V +G +LR++ S KW++ A ++ G+LAP + +E L ++ H D +G++++G+PR++ Q FE+
Sbjct: 18 DSLLTGLMYYRPEDPISYMEMCLQKVRDIGGPEKVQWDTFLSRNLPPINGGQGKKTPHRAEGLPAPQMRRYERLPPIQSQFSIDSDSDMTESSGLIQEYDVFDPNRERPKIIFVIGGPG-SGKGTQSTKMASHFGFICVSVGDILRKQLIHHASSD-RKWELIAQIISKGDLAPPETTIEELKQQFINHQDATGFVVDGFPRDIGQAFTFEE 227 HSP 2 Score: 34.2686 bits (77), Expect = 1.038e-20 Identity = 20/73 (27.40%), Postives = 34/73 (46.58%), Query Frame = 1
Query: 688 FVILVDCEEDTCQQALVQRPPIEGWTDHTPSAIGRRIANYKAYTLPVCKYFDDQQKLKMIDGDKTREEVLHDI 906
VI + C +Q L +R + G D AI RR++ +K + KY+ D+ + D D+ + + DI
Sbjct: 234 LVIFLACSSQRLRQRLERRASLHGRPDDNAHAIDRRLSTFKQNLPLIVKYYQDKGLIARFDADREEDSIFEDI 306 HSP 3 Score: 85.1149 bits (209), Expect = 1.007e-16 Identity = 53/190 (27.89%), Postives = 100/190 (52.63%), Query Frame = 1
Query: 1102 GGPGCGKTTAATEICTRYKDWVHINVNDIIRYRIFDKGVESTNWDCLAKLSLLNDVHLDQNQLVIEHWNINVEFIKEELKTLKSSTQGIILEGFPKDKVQLQQFNIEIGRADLVILLDCDEYYMTTRLLERGERLHRADDDLSNIKKRIIYYKTSGLPVCRYYDERHILNIIPGDRKIAEVLADVISLLE 1671
GGPG GK T +I +Y + H++ D++R + S+ + LS + +++ +LV + ++ +KE + +++G +++G+P++ Q ++F +IG L++ +D M RLL+RGE RADD+ + IKKR+ Y + PV Y+ R I+ I + + +V V + L+
Sbjct: 323 GGPGSGKGTQCEKIVHQY-GYTHLSTGDLLRAEV------SSGSERGKHLSAI----MEKGELV--PLDTVLDMLKEAMIAKADTSKGYLIDGYPREVKQGEEFEKKIGPPSLLLYIDAGSDTMVKRLLKRGETSGRADDNEATIKKRLETYYKATEPVIAMYEGRGIVRKINAEGSVDDVFKQVSTALD 499 HSP 4 Score: 80.1073 bits (196), Expect = 4.374e-15 Identity = 55/222 (24.77%), Postives = 106/222 (47.75%), Query Frame = 1
Query: 1024 IEEIFNIDPEIIRPSDLPQCPIVILLGGPGCGKTTAATEICTRYKDWVHINVNDIIRYRIFDKGVESTNWDCLAKLSLLNDVHLDQNQLVIEHWNINVEFIKEELKTLKSSTQGIILEGFPKDKVQLQQFNIEIGRADLVILLDCDEYYMTTRLLERGERLHRADDDLSNIKKRIIYYKTSGLPVCRYYDERHILNIIPGDRKIAEVLADVISLLELAIMKN 1689
I+E DP RP I+ ++GGPG GK T +T++ + + ++ ++V DI+R ++ W+ +A++ D+ + +E +K++ + +T G +++GFP+D Q F +IG DLVI L C + RL R R DD+ I +R+ +K + + +YY ++ ++ DR+ + D+ ++ + N
Sbjct: 113 IQEYDVFDPNRERPK------IIFVIGGPGSGKGTQSTKMASHF-GFICVSVGDILRKQLIHHASSDRKWELIAQIISKGDLAPPET---------TIEELKQQFINHQDAT-GFVVDGFPRDIGQAFTFEEQIGSPDLVIFLACSSQRLRQRLERRASLHGRPDDNAHAIDRRLSTFKQNLPLIVKYYQDKGLIARFDADREEDSIFEDICCAVQGLLFPN 317 HSP 5 Score: 59.6918 bits (143), Expect = 1.272e-8 Identity = 36/100 (36.00%), Postives = 54/100 (54.00%), Query Frame = 2
Query: 377 AGPGMDKKGLANILTKNYPRFYHVELGRLLREKAETEISKGISKWKVAASLMHCGELAPNDMVLETLIKELNYHTDVS-GYIIEGYPRNLEQMQDFEKFV 673
GPG K + Y + H+ G LLR E+S G + K +++M GEL P D VL+ L + + D S GY+I+GYPR ++Q ++FEK +
Sbjct: 323 GGPGSGKGTQCEKIVHQY-GYTHLSTGDLLR----AEVSSGSERGKHLSAIMEKGELVPLDTVLDMLKEAMIAKADTSKGYLIDGYPREVKQGEEFEKKI 417
BLAST of Adenylate kinase isoenzyme 5 vs. Ensembl Mouse
Match: Ak5 (adenylate kinase 5 [Source:MGI Symbol;Acc:MGI:2677491]) HSP 1 Score: 122.479 bits (306), Expect = 2.095e-53 Identity = 87/326 (26.69%), Postives = 154/326 (47.24%), Query Frame = 1
Query: 664 EICMNRLSFVILVDCEEDTCQQALVQRPPIEGWTDHTPSAIGRRIANYKAYTLPVCKYFDDQQKLKMIDGDKTREEVLHDIG-----KIFKXXXXXXXXXXXXXXXXXXXXYNEIPPPGV---AQVQDIEEIFNIDPEIIRPSDLPQCPIVILLGGPGCGKTTAATEICTRYKDWVHINVNDIIRYRIFDKGVESTNWDCLAKLSLLNDVHLDQNQLVIEHWNINVEFIKEELKTLKSSTQGIILEGFPKDKVQLQQFNIEIGRADLVILLDCDEYYMTTRLLERGERLHRADDDLSNIKKRIIYYKTSGLPVCRYYDERHILNII 1617
+IC L V+ + C ++ L +R +G D A RR+ N+K P+ KYF ++ + D D+ + V HDI K+F + + + ++ + EI G Q D +F D E DL +C I+ L+GGPG GK T ++ +Y + H++ +++R + + S L+ D+ +++ LV + +E +KE + +T+G +++G+P++ Q ++F IG LVI +DC MT RLL+R + R +D +I KR+ Y + +PV YY+ + L +
Sbjct: 233 QICTPDL--VVFLACANQRLKERLQKRAEQQGRPDDNLKATQRRLVNFKQNAAPLVKYFQEKGLIVTFDADRDEDAVFHDISVAVDSKLFPNKEAPMDSSDLDPSMMFDA--GEIIDTGSDYDNQDDDQLNVFGEDTEGGFMEDLRKCKIIFLMGGPGSGKGTQCEKLAEKY-GFTHLSTGELLRQELTSESERS---------KLIRDI-MERGDLV--PSGVVLELLKEAMVASLGNTKGFLIDGYPREVKQGEEFGRRIGDPHLVICMDCSADTMTNRLLQRSQSSQRGEDGAKSIAKRLEAYHRASIPVVTYYERKTQLRKV 541 HSP 2 Score: 108.227 bits (269), Expect = 2.095e-53 Identity = 70/230 (30.43%), Postives = 115/230 (50.00%), Query Frame = 2
Query: 83 NAKDYLAKNEIPQLFECLMTGLMYHRPLSHIDYLQQCLDRIKK-QGVNGVRWDMFLEAKSIPLPPISPSCKE--------------------------EFTAEGVTD-SNTIQLNISYDV--------ALVIFIAGPGMDKKGLANILTKNYPRFYHVELGRLLREKAETEISKGISKWKVAASLMHCGELAPNDMVLETLIKELNYHTDVSGYIIEGYPRNLEQMQDFE 664
+AK+YLA+ +IPQLFE L+ GLM +P I+YL+ CL ++K+ G + V+WD F+ + LPP++ +F+ E TD S T +L Y+V +++ I GPG K + + + Y F ++ +G LLR+K + S KW + A ++ GELAP + + + ++L D G +I+G+PR++ Q FE
Sbjct: 5 DAKEYLARRDIPQLFESLLNGLMCSKPEDPIEYLETCLQKVKELGGCDKVKWDTFVSQEKKTLPPLNGGQSRRSFLRNVMPENSNFPYRRYDRLPPIHQFSIESDTDLSETAELIEEYEVFDPTRPRPKIILVIGGPGSGKGTQSLKIAERYG-FQYISVGELLRKKIHSASSN--RKWSLIAKIITNGELAPQETTITEIKQKLMQIPDEEGIVIDGFPRDVAQALSFE 231 HSP 3 Score: 98.5969 bits (244), Expect = 4.733e-21 Identity = 63/223 (28.25%), Postives = 112/223 (50.22%), Query Frame = 1
Query: 1024 IEEIFNIDPEIIRPSDLPQCPIVILLGGPGCGKTTAATEICTRYKDWVHINVNDIIRYRIFDKGVESTNWDCLAKLSLLNDVHLDQNQLVIEHWNINVEFIKEELKTLKSSTQGIILEGFPKDKVQLQQFNIEIGRADLVILLDCDEYYMTTRLLERGERLHRADDDLSNIKKRIIYYKTSGLPVCRYYDERHILNIIPGDRKIAEVLADVISLLELAIMKNR 1692
IEE DP RP I++++GGPG GK T + +I RY + +I+V +++R +I + W +AK+ + N Q + E IK++L + +GI+++GFP+D Q F +I DLV+ L C + RL +R E+ R DD+L ++R++ +K + P+ +Y+ E+ ++ DR V D+ ++ + N+
Sbjct: 119 IEEYEVFDPTRPRPK------IILVIGGPGSGKGTQSLKIAERY-GFQYISVGELLRKKIH-SASSNRKWSLIAKI-ITNGELAPQETTITE--------IKQKLMQIPDE-EGIVIDGFPRDVAQALSFEDQICTPDLVVFLACANQRLKERLQKRAEQQGRPDDNLKATQRRLVNFKQNAAPLVKYFQEKGLIVTFDADRDEDAVFHDISVAVDSKLFPNK 323 HSP 4 Score: 52.7582 bits (125), Expect = 3.794e-13 Identity = 32/106 (30.19%), Postives = 58/106 (54.72%), Query Frame = 2
Query: 362 LVIFIAGPGMDKKGLANILTKNYPRFYHVELGRLLREKAETEISKGISKWKVAASLMHCGELAPNDMVLETLIKELNYHT--DVSGYIIEGYPRNLEQMQDFEKFV 673
++ + GPG K L + Y F H+ G LLR+ E++ + K+ +M G+L P+ +VLE L+KE + + G++I+GYPR ++Q ++F + +
Sbjct: 378 IIFLMGGPGSGKGTQCEKLAEKYG-FTHLSTGELLRQ----ELTSESERSKLIRDIMERGDLVPSGVVLE-LLKEAMVASLGNTKGFLIDGYPREVKQGEEFGRRI 477 HSP 5 Score: 42.3578 bits (98), Expect = 3.794e-13 Identity = 19/70 (27.14%), Postives = 36/70 (51.43%), Query Frame = 1
Query: 688 FVILVDCEEDTCQQALVQRPPIEGWTDHTPSAIGRRIANYKAYTLPVCKYFDDQQKLKMIDGDKTREEVL 897
VI +DC DT L+QR + +I +R+ Y ++PV Y++ + +L+ ++ + T E+V
Sbjct: 482 LVICMDCSADTMTNRLLQRSQSSQRGEDGAKSIAKRLEAYHRASIPVVTYYERKTQLRKVNAEGTPEQVF 551
BLAST of Adenylate kinase isoenzyme 5 vs. Ensembl Mouse
Match: Ak1 (adenylate kinase 1 [Source:MGI Symbol;Acc:MGI:87977]) HSP 1 Score: 95.9005 bits (237), Expect = 3.980e-22 Identity = 55/200 (27.50%), Postives = 109/200 (54.50%), Query Frame = 1
Query: 1072 LPQCPIVILLGGPGCGKTTAATEICTRYKDWVHINVNDIIRYRIFDKGVESTNWDCLAKLSLLNDVHLDQNQLVIEHWNINVEFIKEELKTLKSSTQGIILEGFPKDKVQLQQFNIEIGRADLVILLDCDEYYMTTRLLERGERLHRADDDLSNIKKRIIYYKTSGLPVCRYYDERHILNIIPGDRKIAEVLADVISLLE 1671
L + I+ ++GGPG GK T +I +Y + H++ D++R + S+ + KLS + +++ +LV + ++ +++ + S+ G +++G+P++ Q ++F +IG+ L++ +D MT RLL+RGE R DD+ IKKR+ Y + PV +YD+R I+ + + + V ++V + L+
Sbjct: 5 LKKAKIIFVVGGPGSGKGTQCEKIVQKY-GYTHLSTGDLLRAEV------SSGSERGKKLSAI----MEKGELV--PLDTVLDMLRDAMLAKVDSSNGFLIDGYPREVKQGEEFEQKIGQPTLLLYVDAGAETMTQRLLKRGETSGRVDDNEETIKKRLETYYNATEPVISFYDKRGIVRKVNAEGTVDTVFSEVCTYLD 191 HSP 2 Score: 59.6918 bits (143), Expect = 1.025e-9 Identity = 37/105 (35.24%), Postives = 58/105 (55.24%), Query Frame = 2
Query: 359 ALVIFI-AGPGMDKKGLANILTKNYPRFYHVELGRLLREKAETEISKGISKWKVAASLMHCGELAPNDMVLETLIKELNYHTDVS-GYIIEGYPRNLEQMQDFEK 667
A +IF+ GPG K + + Y + H+ G LLR E+S G + K +++M GEL P D VL+ L + D S G++I+GYPR ++Q ++FE+
Sbjct: 8 AKIIFVVGGPGSGKGTQCEKIVQKYG-YTHLSTGDLLR----AEVSSGSERGKKLSAIMEKGELVPLDTVLDMLRDAMLAKVDSSNGFLIDGYPREVKQGEEFEQ 107
BLAST of Adenylate kinase isoenzyme 5 vs. Ensembl Mouse
Match: Ak1 (adenylate kinase 1 [Source:MGI Symbol;Acc:MGI:87977]) HSP 1 Score: 95.9005 bits (237), Expect = 3.980e-22 Identity = 55/200 (27.50%), Postives = 109/200 (54.50%), Query Frame = 1
Query: 1072 LPQCPIVILLGGPGCGKTTAATEICTRYKDWVHINVNDIIRYRIFDKGVESTNWDCLAKLSLLNDVHLDQNQLVIEHWNINVEFIKEELKTLKSSTQGIILEGFPKDKVQLQQFNIEIGRADLVILLDCDEYYMTTRLLERGERLHRADDDLSNIKKRIIYYKTSGLPVCRYYDERHILNIIPGDRKIAEVLADVISLLE 1671
L + I+ ++GGPG GK T +I +Y + H++ D++R + S+ + KLS + +++ +LV + ++ +++ + S+ G +++G+P++ Q ++F +IG+ L++ +D MT RLL+RGE R DD+ IKKR+ Y + PV +YD+R I+ + + + V ++V + L+
Sbjct: 5 LKKAKIIFVVGGPGSGKGTQCEKIVQKY-GYTHLSTGDLLRAEV------SSGSERGKKLSAI----MEKGELV--PLDTVLDMLRDAMLAKVDSSNGFLIDGYPREVKQGEEFEQKIGQPTLLLYVDAGAETMTQRLLKRGETSGRVDDNEETIKKRLETYYNATEPVISFYDKRGIVRKVNAEGTVDTVFSEVCTYLD 191 HSP 2 Score: 59.6918 bits (143), Expect = 1.025e-9 Identity = 37/105 (35.24%), Postives = 58/105 (55.24%), Query Frame = 2
Query: 359 ALVIFI-AGPGMDKKGLANILTKNYPRFYHVELGRLLREKAETEISKGISKWKVAASLMHCGELAPNDMVLETLIKELNYHTDVS-GYIIEGYPRNLEQMQDFEK 667
A +IF+ GPG K + + Y + H+ G LLR E+S G + K +++M GEL P D VL+ L + D S G++I+GYPR ++Q ++FE+
Sbjct: 8 AKIIFVVGGPGSGKGTQCEKIVQKYG-YTHLSTGDLLR----AEVSSGSERGKKLSAIMEKGELVPLDTVLDMLRDAMLAKVDSSNGFLIDGYPREVKQGEEFEQ 107
BLAST of Adenylate kinase isoenzyme 5 vs. Ensembl Mouse
Match: Ak5 (adenylate kinase 5 [Source:MGI Symbol;Acc:MGI:2677491]) HSP 1 Score: 95.5153 bits (236), Expect = 5.102e-22 Identity = 57/196 (29.08%), Postives = 101/196 (51.53%), Query Frame = 1
Query: 1012 QVQDIEEIFNIDPEIIRPSDLPQCPIVILLGGPGCGKTTAATEICTRYKDWVHINVNDIIRYRIFDKGVESTNWDCLAKLSLLNDVHLDQNQLVIEHWNINVEFIKEELKTLKSSTQGIILEGFPKDKVQLQQFNIEIGRADLVILLDCDEYYMTTRLLERGERLHRADDDLSNIKKRIIYYKTSGLPVCRYYDER 1599
Q D +F D E DL +C I+ L+GGPG GK T ++ +Y + H++ +++R + + S L+ D+ +++ LV + +E +KE + +T+G +++G+P++ Q ++F IG LVI +DC MT RLL+R + R +D +I KR+ Y + +PV YY+ +
Sbjct: 12 QDDDQLNVFGEDTEGGFMEDLRKCKIIFLMGGPGSGKGTQCEKLAEKY-GFTHLSTGELLRQELTSESERS---------KLIRDI-MERGDLVPS--GVVLELLKEAMVASLGNTKGFLIDGYPREVKQGEEFGRRIGDPHLVICMDCSADTMTNRLLQRSQSSQRGEDGAKSIAKRLEAYHRASIPVVTYYERK 194 HSP 2 Score: 52.7582 bits (125), Expect = 4.005e-11 Identity = 32/106 (30.19%), Postives = 58/106 (54.72%), Query Frame = 2
Query: 362 LVIFIAGPGMDKKGLANILTKNYPRFYHVELGRLLREKAETEISKGISKWKVAASLMHCGELAPNDMVLETLIKELNYHT--DVSGYIIEGYPRNLEQMQDFEKFV 673
++ + GPG K L + Y F H+ G LLR+ E++ + K+ +M G+L P+ +VLE L+KE + + G++I+GYPR ++Q ++F + +
Sbjct: 37 IIFLMGGPGSGKGTQCEKLAEKYG-FTHLSTGELLRQ----ELTSESERSKLIRDIMERGDLVPSGVVLE-LLKEAMVASLGNTKGFLIDGYPREVKQGEEFGRRI 136 HSP 3 Score: 35.4242 bits (80), Expect = 4.005e-11 Identity = 16/58 (27.59%), Postives = 29/58 (50.00%), Query Frame = 1
Query: 688 FVILVDCEEDTCQQALVQRPPIEGWTDHTPSAIGRRIANYKAYTLPVCKYFDDQQKLK 861
VI +DC DT L+QR + +I +R+ Y ++PV Y++ + +L+
Sbjct: 141 LVICMDCSADTMTNRLLQRSQSSQRGEDGAKSIAKRLEAYHRASIPVVTYYERKTQLR 198
BLAST of Adenylate kinase isoenzyme 5 vs. Ensembl Mouse
Match: Ak1 (adenylate kinase 1 [Source:MGI Symbol;Acc:MGI:87977]) HSP 1 Score: 95.5153 bits (236), Expect = 6.268e-22 Identity = 55/200 (27.50%), Postives = 109/200 (54.50%), Query Frame = 1
Query: 1072 LPQCPIVILLGGPGCGKTTAATEICTRYKDWVHINVNDIIRYRIFDKGVESTNWDCLAKLSLLNDVHLDQNQLVIEHWNINVEFIKEELKTLKSSTQGIILEGFPKDKVQLQQFNIEIGRADLVILLDCDEYYMTTRLLERGERLHRADDDLSNIKKRIIYYKTSGLPVCRYYDERHILNIIPGDRKIAEVLADVISLLE 1671
L + I+ ++GGPG GK T +I +Y + H++ D++R + S+ + KLS + +++ +LV + ++ +++ + S+ G +++G+P++ Q ++F +IG+ L++ +D MT RLL+RGE R DD+ IKKR+ Y + PV +YD+R I+ + + + V ++V + L+
Sbjct: 21 LKKAKIIFVVGGPGSGKGTQCEKIVQKY-GYTHLSTGDLLRAEV------SSGSERGKKLSAI----MEKGELV--PLDTVLDMLRDAMLAKVDSSNGFLIDGYPREVKQGEEFEQKIGQPTLLLYVDAGAETMTQRLLKRGETSGRVDDNEETIKKRLETYYNATEPVISFYDKRGIVRKVNAEGTVDTVFSEVCTYLD 207 HSP 2 Score: 60.077 bits (144), Expect = 9.506e-10 Identity = 37/107 (34.58%), Postives = 59/107 (55.14%), Query Frame = 2
Query: 359 ALVIFI-AGPGMDKKGLANILTKNYPRFYHVELGRLLREKAETEISKGISKWKVAASLMHCGELAPNDMVLETLIKELNYHTDVS-GYIIEGYPRNLEQMQDFEKFV 673
A +IF+ GPG K + + Y + H+ G LLR E+S G + K +++M GEL P D VL+ L + D S G++I+GYPR ++Q ++FE+ +
Sbjct: 24 AKIIFVVGGPGSGKGTQCEKIVQKYG-YTHLSTGDLLR----AEVSSGSERGKKLSAIMEKGELVPLDTVLDMLRDAMLAKVDSSNGFLIDGYPREVKQGEEFEQKI 125
BLAST of Adenylate kinase isoenzyme 5 vs. UniProt/SwissProt
Match: sp|A4IFD0|KAD5_BOVIN (Adenylate kinase isoenzyme 5 OS=Bos taurus OX=9913 GN=Ak5 PE=2 SV=1) HSP 1 Score: 122.865 bits (307), Expect = 5.119e-53 Identity = 89/336 (26.49%), Postives = 162/336 (48.21%), Query Frame = 1
Query: 664 EICMNRLSFVILVDCEEDTCQQALVQRPPIEGWTDHTPSAIGRRIANYKAYTLPVCKYFDDQQKLKMIDGDKTREEVLHDIG-----KIFKXXXXXXXXXXXXXXXXXXXXYNEIPPPGVA---QVQDIEEIFNIDPEIIRPSDLPQCPIVILLGGPGCGKTTAATEICTRYKDWVHINVNDIIRYRIFDKGVESTNWDCLAKLSLLNDVHLDQNQLVIEHWNINVEFIKEELKTLKSSTQGIILEGFPKDKVQLQQFNIEIGRADLVILLDCDEYYMTTRLLERGERLHRADDDLSNIKKRIIYYKTSGLPVCRYYDERHILNIIPGDRKIAEVL 1647
+IC L V+ + C ++ L++R +G D A RR+ N+K P+ KYF ++ + D D+ +EV +DI K+F + + ++ + E+ G Q D +F D DL +C I+ ++GGPG GK T ++ +Y + H++ +++++ + + S L+ D+ +++ +LV I +E +KE + S+T+G +++G+P++ Q ++F IG LVI +DC MT RLL+R +ADD+ + I KR+ Y + +PV YY+ + L+ I + EV
Sbjct: 233 QICTPDL--VVFLACTNQRLKERLLKRAEQQGRPDDNLKATQRRLMNFKQNAAPLVKYFQEKGLIMTFDADRDEDEVFYDISMAVDSKLFPNKEAAAGSSDLDPSMMLDT--GEVIDTGSDYEDQGDDQLNVFGEDTMGGFMEDLKKCKIIFMIGGPGSGKGTQCGKLAEKY-GFTHLSTDELLQNELSSESGRS---------KLIRDI-MERGELV--PSGIILELLKEAMVASLSNTKGFLIDGYPREVKQGEEFGRRIGDPHLVICMDCSADTMTNRLLQRSRNSPQADDNTTTIAKRLETYYRASIPVVAYYETKTQLHKINAEGTPEEVF 551 HSP 2 Score: 108.997 bits (271), Expect = 5.119e-53 Identity = 70/229 (30.57%), Postives = 114/229 (49.78%), Query Frame = 2
Query: 86 AKDYLAKNEIPQLFECLMTGLMYHRPLSHIDYLQQCLDRIKK-QGVNGVRWDMFLEAKSIPLPPISPSCKE--------------------------EFTAEGVTD-SNTIQLNISYDV--------ALVIFIAGPGMDKKGLANILTKNYPRFYHVELGRLLREKAETEISKGISKWKVAASLMHCGELAPNDMVLETLIKELNYHTDVSGYIIEGYPRNLEQMQDFE 664
AK+YLA+ EIPQLFE L+ GLM +P ++YL+ CL ++K+ G + V+WD F+ + LPP++ +F+ E TD S T +L Y+V +++ I GPG K + + + Y F ++ +G LLR+K + S KW + A ++ GELAP + + + ++L D G +I+G+PR++ Q FE
Sbjct: 6 AKEYLARREIPQLFESLLNGLMCSKPEDPVEYLESCLQKVKELGGCDKVKWDTFVSQEKKTLPPLNGGQSRRSFLRNVMPENSNFPYRRYDRLPPIHQFSIESDTDLSETAELIEEYEVFDPTRPRPKIILVIGGPGSGKGTQSLKIAERYG-FQYISVGELLRKKIHSTSSN--RKWSLIAKIITTGELAPQETTITEIKQKLMQMPDEVGIVIDGFPRDVAQALSFE 231 HSP 3 Score: 102.064 bits (253), Expect = 2.851e-21 Identity = 64/223 (28.70%), Postives = 113/223 (50.67%), Query Frame = 1
Query: 1024 IEEIFNIDPEIIRPSDLPQCPIVILLGGPGCGKTTAATEICTRYKDWVHINVNDIIRYRIFDKGVESTNWDCLAKLSLLNDVHLDQNQLVIEHWNINVEFIKEELKTLKSSTQGIILEGFPKDKVQLQQFNIEIGRADLVILLDCDEYYMTTRLLERGERLHRADDDLSNIKKRIIYYKTSGLPVCRYYDERHILNIIPGDRKIAEVLADVISLLELAIMKNR 1692
IEE DP RP I++++GGPG GK T + +I RY + +I+V +++R +I + W +AK+ + +L + I IK++L + GI+++GFP+D Q F +I DLV+ L C + RLL+R E+ R DD+L ++R++ +K + P+ +Y+ E+ ++ DR EV D+ ++ + N+
Sbjct: 119 IEEYEVFDPTRPRPK------IILVIGGPGSGKGTQSLKIAERY-GFQYISVGELLRKKIHSTS-SNRKWSLIAKI-------ITTGELAPQETTITE--IKQKLMQMPDEV-GIVIDGFPRDVAQALSFEDQICTPDLVVFLACTNQRLKERLLKRAEQQGRPDDNLKATQRRLMNFKQNAAPLVKYFQEKGLIMTFDADRDEDEVFYDISMAVDSKLFPNK 323
BLAST of Adenylate kinase isoenzyme 5 vs. UniProt/SwissProt
Match: sp|Q920P5|KAD5_MOUSE (Adenylate kinase isoenzyme 5 OS=Mus musculus OX=10090 GN=Ak5 PE=1 SV=2) HSP 1 Score: 122.479 bits (306), Expect = 1.273e-52 Identity = 87/326 (26.69%), Postives = 154/326 (47.24%), Query Frame = 1
Query: 664 EICMNRLSFVILVDCEEDTCQQALVQRPPIEGWTDHTPSAIGRRIANYKAYTLPVCKYFDDQQKLKMIDGDKTREEVLHDIG-----KIFKXXXXXXXXXXXXXXXXXXXXYNEIPPPGV---AQVQDIEEIFNIDPEIIRPSDLPQCPIVILLGGPGCGKTTAATEICTRYKDWVHINVNDIIRYRIFDKGVESTNWDCLAKLSLLNDVHLDQNQLVIEHWNINVEFIKEELKTLKSSTQGIILEGFPKDKVQLQQFNIEIGRADLVILLDCDEYYMTTRLLERGERLHRADDDLSNIKKRIIYYKTSGLPVCRYYDERHILNII 1617
+IC L V+ + C ++ L +R +G D A RR+ N+K P+ KYF ++ + D D+ + V HDI K+F + + + ++ + EI G Q D +F D E DL +C I+ L+GGPG GK T ++ +Y + H++ +++R + + S L+ D+ +++ LV + +E +KE + +T+G +++G+P++ Q ++F IG LVI +DC MT RLL+R + R +D +I KR+ Y + +PV YY+ + L +
Sbjct: 233 QICTPDL--VVFLACANQRLKERLQKRAEQQGRPDDNLKATQRRLVNFKQNAAPLVKYFQEKGLIVTFDADRDEDAVFHDISVAVDSKLFPNKEAPMDSSDLDPSMMFDA--GEIIDTGSDYDNQDDDQLNVFGEDTEGGFMEDLRKCKIIFLMGGPGSGKGTQCEKLAEKY-GFTHLSTGELLRQELTSESERS---------KLIRDI-MERGDLV--PSGVVLELLKEAMVASLGNTKGFLIDGYPREVKQGEEFGRRIGDPHLVICMDCSADTMTNRLLQRSQSSQRGEDGAKSIAKRLEAYHRASIPVVTYYERKTQLRKV 541 HSP 2 Score: 108.227 bits (269), Expect = 1.273e-52 Identity = 70/230 (30.43%), Postives = 115/230 (50.00%), Query Frame = 2
Query: 83 NAKDYLAKNEIPQLFECLMTGLMYHRPLSHIDYLQQCLDRIKK-QGVNGVRWDMFLEAKSIPLPPISPSCKE--------------------------EFTAEGVTD-SNTIQLNISYDV--------ALVIFIAGPGMDKKGLANILTKNYPRFYHVELGRLLREKAETEISKGISKWKVAASLMHCGELAPNDMVLETLIKELNYHTDVSGYIIEGYPRNLEQMQDFE 664
+AK+YLA+ +IPQLFE L+ GLM +P I+YL+ CL ++K+ G + V+WD F+ + LPP++ +F+ E TD S T +L Y+V +++ I GPG K + + + Y F ++ +G LLR+K + S KW + A ++ GELAP + + + ++L D G +I+G+PR++ Q FE
Sbjct: 5 DAKEYLARRDIPQLFESLLNGLMCSKPEDPIEYLETCLQKVKELGGCDKVKWDTFVSQEKKTLPPLNGGQSRRSFLRNVMPENSNFPYRRYDRLPPIHQFSIESDTDLSETAELIEEYEVFDPTRPRPKIILVIGGPGSGKGTQSLKIAERYG-FQYISVGELLRKKIHSASSN--RKWSLIAKIITNGELAPQETTITEIKQKLMQIPDEEGIVIDGFPRDVAQALSFE 231 HSP 3 Score: 98.5969 bits (244), Expect = 3.311e-20 Identity = 63/223 (28.25%), Postives = 112/223 (50.22%), Query Frame = 1
Query: 1024 IEEIFNIDPEIIRPSDLPQCPIVILLGGPGCGKTTAATEICTRYKDWVHINVNDIIRYRIFDKGVESTNWDCLAKLSLLNDVHLDQNQLVIEHWNINVEFIKEELKTLKSSTQGIILEGFPKDKVQLQQFNIEIGRADLVILLDCDEYYMTTRLLERGERLHRADDDLSNIKKRIIYYKTSGLPVCRYYDERHILNIIPGDRKIAEVLADVISLLELAIMKNR 1692
IEE DP RP I++++GGPG GK T + +I RY + +I+V +++R +I + W +AK+ + N Q + E IK++L + +GI+++GFP+D Q F +I DLV+ L C + RL +R E+ R DD+L ++R++ +K + P+ +Y+ E+ ++ DR V D+ ++ + N+
Sbjct: 119 IEEYEVFDPTRPRPK------IILVIGGPGSGKGTQSLKIAERY-GFQYISVGELLRKKIH-SASSNRKWSLIAKI-ITNGELAPQETTITE--------IKQKLMQIPDE-EGIVIDGFPRDVAQALSFEDQICTPDLVVFLACANQRLKERLQKRAEQQGRPDDNLKATQRRLVNFKQNAAPLVKYFQEKGLIVTFDADRDEDAVFHDISVAVDSKLFPNK 323 HSP 4 Score: 52.7582 bits (125), Expect = 2.307e-12 Identity = 32/106 (30.19%), Postives = 58/106 (54.72%), Query Frame = 2
Query: 362 LVIFIAGPGMDKKGLANILTKNYPRFYHVELGRLLREKAETEISKGISKWKVAASLMHCGELAPNDMVLETLIKELNYHT--DVSGYIIEGYPRNLEQMQDFEKFV 673
++ + GPG K L + Y F H+ G LLR+ E++ + K+ +M G+L P+ +VLE L+KE + + G++I+GYPR ++Q ++F + +
Sbjct: 378 IIFLMGGPGSGKGTQCEKLAEKYG-FTHLSTGELLRQ----ELTSESERSKLIRDIMERGDLVPSGVVLE-LLKEAMVASLGNTKGFLIDGYPREVKQGEEFGRRI 477 HSP 5 Score: 42.3578 bits (98), Expect = 2.307e-12 Identity = 19/70 (27.14%), Postives = 36/70 (51.43%), Query Frame = 1
Query: 688 FVILVDCEEDTCQQALVQRPPIEGWTDHTPSAIGRRIANYKAYTLPVCKYFDDQQKLKMIDGDKTREEVL 897
VI +DC DT L+QR + +I +R+ Y ++PV Y++ + +L+ ++ + T E+V
Sbjct: 482 LVICMDCSADTMTNRLLQRSQSSQRGEDGAKSIAKRLEAYHRASIPVVTYYERKTQLRKVNAEGTPEQVF 551
BLAST of Adenylate kinase isoenzyme 5 vs. UniProt/SwissProt
Match: sp|Q9Y6K8|KAD5_HUMAN (Adenylate kinase isoenzyme 5 OS=Homo sapiens OX=9606 GN=AK5 PE=1 SV=2) HSP 1 Score: 114.775 bits (286), Expect = 7.131e-51 Identity = 87/326 (26.69%), Postives = 151/326 (46.32%), Query Frame = 1
Query: 664 EICMNRLSFVILVDCEEDTCQQALVQRPPIEGWTDHTPSAIGRRIANYKAYTLPVCKYFDDQQKLKMIDGDKTREEVLHDIG-----KIFKXXXXXXXXXXXXXXXXXXXXYNEIPPPGVA---QVQDIEEIFNIDPEIIRPSDLPQCPIVILLGGPGCGKTTAATEICTRYKDWVHINVNDIIRYRIFDKGVESTNWDCLAKLSLLNDVHLDQNQLVIEHWNINVEFIKEELKTLKSSTQGIILEGFPKDKVQLQQFNIEIGRADLVILLDCDEYYMTTRLLERGERLHRADDDLSNIKKRIIYYKTSGLPVCRYYDERHILNII 1617
+IC L V+ + C ++ L++R +G D A RR+ N+K P+ KYF ++ + D D+ +EV +DI K+F + + ++ + EI G Q D +F D DL +C I+ ++GGPG GK T ++ +Y + H++ +++R + + S L+ D+ +++ LV I +E +KE + T+G +++G+P++ Q ++F IG LVI +DC MT RLL+R DD I KR+ Y + +PV YY+ + L+ I
Sbjct: 233 QICTPDL--VVFLACANQRLKERLLKRAEQQGRPDDNVKATQRRLMNFKQNAAPLVKYFQEKGLIMTFDADRDEDEVFYDISMAVDNKLFPNKEAAAGSSDLDPSMILDT--GEIIDTGSDYEDQGDDQLNVFGEDTMGGFMEDLRKCKIIFIIGGPGSGKGTQCEKLVEKY-GFTHLSTGELLREELASESERS---------KLIRDI-MERGDLV--PSGIVLELLKEAMVASLGDTRGFLIDGYPREVKQGEEFGRRIGDPQLVICMDCSADTMTNRLLQRSRSSLPVDDTTKTIAKRLEAYYRASIPVIAYYETKTQLHKI 541 HSP 2 Score: 109.768 bits (273), Expect = 7.131e-51 Identity = 70/230 (30.43%), Postives = 115/230 (50.00%), Query Frame = 2
Query: 83 NAKDYLAKNEIPQLFECLMTGLMYHRPLSHIDYLQQCLDRIKK-QGVNGVRWDMFLEAKSIPLPPISPSCKE--------------------------EFTAEGVTD-SNTIQLNISYDV--------ALVIFIAGPGMDKKGLANILTKNYPRFYHVELGRLLREKAETEISKGISKWKVAASLMHCGELAPNDMVLETLIKELNYHTDVSGYIIEGYPRNLEQMQDFE 664
+AK+YLA+ EIPQLFE L+ GLM +P ++YL+ CL ++K+ G + V+WD F+ + LPP++ +F+ E TD S T +L Y+V +++ I GPG K + + + Y F ++ +G LLR+K + S KW + A ++ GELAP + + + ++L D G +I+G+PR++ Q FE
Sbjct: 5 DAKEYLARREIPQLFESLLNGLMCSKPEDPVEYLESCLQKVKELGGCDKVKWDTFVSQEKKTLPPLNGGQSRRSFLRNVMPENSNFPYRRYDRLPPIHQFSIESDTDLSETAELIEEYEVFDPTRPRPKIILVIGGPGSGKGTQSLKIAERYG-FQYISVGELLRKKIHSTSSN--RKWSLIAKIITTGELAPQETTITEIKQKLMQIPDEEGIVIDGFPRDVAQALSFE 231 HSP 3 Score: 100.523 bits (249), Expect = 9.941e-21 Identity = 63/223 (28.25%), Postives = 114/223 (51.12%), Query Frame = 1
Query: 1024 IEEIFNIDPEIIRPSDLPQCPIVILLGGPGCGKTTAATEICTRYKDWVHINVNDIIRYRIFDKGVESTNWDCLAKLSLLNDVHLDQNQLVIEHWNINVEFIKEELKTLKSSTQGIILEGFPKDKVQLQQFNIEIGRADLVILLDCDEYYMTTRLLERGERLHRADDDLSNIKKRIIYYKTSGLPVCRYYDERHILNIIPGDRKIAEVLADVISLLELAIMKNR 1692
IEE DP RP I++++GGPG GK T + +I RY + +I+V +++R +I + W +AK+ + +L + I IK++L + +GI+++GFP+D Q F +I DLV+ L C + RLL+R E+ R DD++ ++R++ +K + P+ +Y+ E+ ++ DR EV D+ ++ + N+
Sbjct: 119 IEEYEVFDPTRPRPK------IILVIGGPGSGKGTQSLKIAERY-GFQYISVGELLRKKIHSTS-SNRKWSLIAKI-------ITTGELAPQETTITE--IKQKLMQIPDE-EGIVIDGFPRDVAQALSFEDQICTPDLVVFLACANQRLKERLLKRAEQQGRPDDNVKATQRRLMNFKQNAAPLVKYFQEKGLIMTFDADRDEDEVFYDISMAVDNKLFPNK 323 HSP 4 Score: 56.9954 bits (136), Expect = 9.793e-14 Identity = 35/106 (33.02%), Postives = 58/106 (54.72%), Query Frame = 2
Query: 362 LVIFIAGPGMDKKGLANILTKNYPRFYHVELGRLLREKAETEISKGISKWKVAASLMHCGELAPNDMVLETLIKELNYHT--DVSGYIIEGYPRNLEQMQDFEKFV 673
++ I GPG K L + Y F H+ G LLRE E++ + K+ +M G+L P+ +VLE L+KE + D G++I+GYPR ++Q ++F + +
Sbjct: 378 IIFIIGGPGSGKGTQCEKLVEKYG-FTHLSTGELLRE----ELASESERSKLIRDIMERGDLVPSGIVLE-LLKEAMVASLGDTRGFLIDGYPREVKQGEEFGRRI 477 HSP 5 Score: 42.743 bits (99), Expect = 9.793e-14 Identity = 22/70 (31.43%), Postives = 35/70 (50.00%), Query Frame = 1
Query: 688 FVILVDCEEDTCQQALVQRPPIEGWTDHTPSAIGRRIANYKAYTLPVCKYFDDQQKLKMIDGDKTREEVL 897
VI +DC DT L+QR D T I +R+ Y ++PV Y++ + +L I+ + T E+V
Sbjct: 482 LVICMDCSADTMTNRLLQRSRSSLPVDDTTKTIAKRLEAYYRASIPVIAYYETKTQLHKINAEGTPEDVF 551
BLAST of Adenylate kinase isoenzyme 5 vs. UniProt/SwissProt
Match: sp|Q20140|KAD1_CAEEL (Adenylate kinase isoenzyme 1 OS=Caenorhabditis elegans OX=6239 GN=F38B2.4 PE=2 SV=1) HSP 1 Score: 98.2117 bits (243), Expect = 5.366e-22 Identity = 60/211 (28.44%), Postives = 102/211 (48.34%), Query Frame = 1
Query: 1057 IRPSDLPQCPIVILLGGPGCGKTTAATEICTRYKDWVHINVNDIIRYRIFDKGVESTNWDCLAKLSLLNDVHLDQNQLVIEHWNINVEFIKEE-LKTLKSSTQGIILEGFPKDKVQLQQFNIEIGRADLVILLDCDEYYMTTRLLERGERLHRADDDLSNIKKRIIYYKTSGLPVCRYYDERHILNIIPGDRKIAEVLADVISLLELAIMK 1686
+ P PI ++GGPG GK T +I +Y H++ D++R + + ++ LV + ++ +KE LK ++ ++G +++G+P++ Q QQF EI A LV+ D E + RLL R + RADD+ IKKR+ + TS PV YY+ + L I + + ++ A V++ L+ A K
Sbjct: 12 LAPLKAAGVPIFFIVGGPGSGKGTQCDKIVAKY-GLTHLSSGDLLRDEVKSGSPRGAQLTAI----------MESGALV--PLEVVLDLVKEAMLKAIEKGSKGFLIDGYPREVAQGQQFESEIQEAKLVLFFDVAEETLVKRLLHRAQTSGRADDNADTIKKRLHTFVTSTAPVVDYYESKGKLVRINAEGSVDDIFAVVVANLDKATSK 209
BLAST of Adenylate kinase isoenzyme 5 vs. UniProt/SwissProt
Match: sp|Q9R0Y5|KAD1_MOUSE (Adenylate kinase isoenzyme 1 OS=Mus musculus OX=10090 GN=Ak1 PE=1 SV=1) HSP 1 Score: 95.9005 bits (237), Expect = 2.784e-21 Identity = 55/200 (27.50%), Postives = 109/200 (54.50%), Query Frame = 1
Query: 1072 LPQCPIVILLGGPGCGKTTAATEICTRYKDWVHINVNDIIRYRIFDKGVESTNWDCLAKLSLLNDVHLDQNQLVIEHWNINVEFIKEELKTLKSSTQGIILEGFPKDKVQLQQFNIEIGRADLVILLDCDEYYMTTRLLERGERLHRADDDLSNIKKRIIYYKTSGLPVCRYYDERHILNIIPGDRKIAEVLADVISLLE 1671
L + I+ ++GGPG GK T +I +Y + H++ D++R + S+ + KLS + +++ +LV + ++ +++ + S+ G +++G+P++ Q ++F +IG+ L++ +D MT RLL+RGE R DD+ IKKR+ Y + PV +YD+R I+ + + + V ++V + L+
Sbjct: 5 LKKAKIIFVVGGPGSGKGTQCEKIVQKY-GYTHLSTGDLLRAEV------SSGSERGKKLSAI----MEKGELV--PLDTVLDMLRDAMLAKVDSSNGFLIDGYPREVKQGEEFEQKIGQPTLLLYVDAGAETMTQRLLKRGETSGRVDDNEETIKKRLETYYNATEPVISFYDKRGIVRKVNAEGTVDTVFSEVCTYLD 191 HSP 2 Score: 59.6918 bits (143), Expect = 7.170e-9 Identity = 37/105 (35.24%), Postives = 58/105 (55.24%), Query Frame = 2
Query: 359 ALVIFI-AGPGMDKKGLANILTKNYPRFYHVELGRLLREKAETEISKGISKWKVAASLMHCGELAPNDMVLETLIKELNYHTDVS-GYIIEGYPRNLEQMQDFEK 667
A +IF+ GPG K + + Y + H+ G LLR E+S G + K +++M GEL P D VL+ L + D S G++I+GYPR ++Q ++FE+
Sbjct: 8 AKIIFVVGGPGSGKGTQCEKIVQKYG-YTHLSTGDLLR----AEVSSGSERGKKLSAIMEKGELVPLDTVLDMLRDAMLAKVDSSNGFLIDGYPREVKQGEEFEQ 107
BLAST of Adenylate kinase isoenzyme 5 vs. TrEMBL
Match: A0A074ZDL2 (Uncharacterized protein OS=Opisthorchis viverrini OX=6198 GN=T265_10351 PE=4 SV=1) HSP 1 Score: 222.631 bits (566), Expect = 3.332e-105 Identity = 124/355 (34.93%), Postives = 197/355 (55.49%), Query Frame = 1
Query: 667 ICMNRLSFVILVDCEEDTCQQALVQRPPIEG-WTDHTPSAIGRRIANYKAYTLPVCKYFDDQQKLKMIDGDKTREEVLHDI---------GKIFKXXXXXXXXXXXXXXXXXXXXYNEIPPPGVAQVQDIEEIFNIDPEIIRPSDLPQCPIVILLGGPGCGKTTAATEICTRYKDWVHINVNDIIRYRIFD--KGVESTNWDCLAKLSLLNDVHLDQNQLVIEHWNINVEFIKEELKTLKSSTQGIILEGFPKDKVQLQQFNIEIGRADLVILLDCDEYYMTTRLLERGERLHRADDDLSNIKKRIIYYKTSGLPVCRYYDERHILNIIPGDRKIAEVLADVISLLELAIMKNRC 1695
I + L+ + L+D E+ CQQ LV+R + W D+ P+AI RI +K TLP+CK D KL+++DG+ E + D+ GK+ S+ + T+ + + PG V +I I + R DLP CPI++L GGPG G++ A +C R H NV + +R R+ D +G +WD +A+ +D + +++++ E+WN+ V+ +++E T+ +T+ +++EGFP D+ QL FN IG ADL +LLDC+E + RLL+R RL R +D+ + RI+++K LPV R+YDER L IP DR VL DV++++E + K C
Sbjct: 222 INLENLACIFLIDATEEYCQQQLVERGQSDDYWKDYLPAAIANRICMFKLQTLPMCKTIDADGKLRVVDGEIKPEHIARDMRTVCEYVLSGKV-TGPSSKPTPGSVPDRPMTKIGHGMMGCPGQPPVFNIPRIVPAFADNGRVEDLPTCPIILLFGGPGSGRSEQARALCERLPGLKHFNVTEFLRNRVLDHIEGDSQKDWDVVARRVHSSDPPMPKDRIIPEYWNVQVDILRQEFNTVAENTKAVVIEGFPNDETQLNIFNQHIGGADLAVLLDCEENTLQKRLLKRYTRLSRTEDEETVALHRILFFKHCTLPVIRHYDERSTLVTIPADRDQELVLNDVVTVVEYFLGKQEC 575 HSP 2 Score: 191.045 bits (484), Expect = 3.332e-105 Identity = 89/223 (39.91%), Postives = 142/223 (63.68%), Query Frame = 2
Query: 47 MQTDRRCLATPRNAKDYLAKNEIPQLFECLMTGLMYHRPLSHIDYLQQCLDRIKKQGVNGVRWDMFLEAKSIPLPPIS-------PSCKEEFTAEGVTDS-------NTIQLNISYDVALVIFIAGPGMDKKGLANILTKNYPRFYHVELGRLLREKAETEISKGISKWKVAASLMHCGELAPNDMVLETLIKELNYHTDVSGYIIEGYPRNLEQMQDFEKFV 673
M+ +R + TP K+YL+KN IPQLFECLMTGLMYHRP +++YLQ+CL+++K++GV VRWD+FLE ++ P PP+ P+ +A S +++++ I + +++ + GPG++K + L +YP F H+ +G LLR +A+ E+ + SKW + ++ GEL P DMV+E+LI LN H D SG+II+G+PR +Q ++F+ +
Sbjct: 1 MEVMKRTI-TPAETKEYLSKNGIPQLFECLMTGLMYHRPTDYLNYLQECLEKVKRKGVTEVRWDLFLENRTSPPPPVVTKRGMTIPTANANSSALNSMSSYMPLPGIDSLKVRIRPNASIICVLGGPGVNKSSYSQGLINHYPTFVHISMGHLLRCRAKLEVERKGSKWTKSVEQINAGELLPQDMVIESLIWHLNQHADASGFIIDGFPRTQQQYEEFKAHI 222 HSP 3 Score: 77.0258 bits (188), Expect = 8.876e-11 Identity = 55/207 (26.57%), Postives = 96/207 (46.38%), Query Frame = 1
Query: 1075 PQCPIVILLGGPGCGKTTAATEICTRYKDWVHINVNDIIRYRIFDKGVESTNWDCLAKLSLLNDVHLDQNQLVIEH--WNINVEFIKEELKTLKSSTQGIILEGFPKDKVQLQQFNIEIGRADL--VILLDCDEYYMTTRLLERGERLHRADDDL-SNIKKRIIYYKTSGLPVCRYYDERHILNIIPGDRKIAEVLADVISLLELAI 1680
P I+ +LGGPG K++ + + Y +VHI++ ++R R VE + +N L +VIE W++N + G I++GFP+ + Q ++F I +L + L+D E Y +L+ERG+ D L + I RI +K LP+C+ D L ++ G+ K + D+ ++ E +
Sbjct: 115 PNASIICVLGGPGVNKSSYSQGLINHYPTFVHISMGHLLRCRA-KLEVERKGSKWTKSVEQINAGELLPQDMVIESLIWHLNQH----------ADASGFIIDGFPRTQQQYEEFKAHINLENLACIFLIDATEEYCQQQLVERGQSDDYWKDYLPAAIANRICMFKLQTLPMCKTIDADGKLRVVDGEIKPEHIARDMRTVCEYVL 310
BLAST of Adenylate kinase isoenzyme 5 vs. TrEMBL
Match: A0A3R7JNZ7 (Adenylate kinase isoenzyme 5 OS=Clonorchis sinensis OX=79923 GN=Ak5 PE=4 SV=1) HSP 1 Score: 218.394 bits (555), Expect = 3.041e-103 Identity = 124/355 (34.93%), Postives = 196/355 (55.21%), Query Frame = 1
Query: 667 ICMNRLSFVILVDCEEDTCQQALVQRPPIEG-WTDHTPSAIGRRIANYKAYTLPVCKYFDDQQKLKMIDGDKTREEVLHDI---------GKIFKXXXXXXXXXXXXXXXXXXXXYNEIPPPGVAQVQDIEEIFNIDPEIIRPSDLPQCPIVILLGGPGCGKTTAATEICTRYKDWVHINVNDIIRYRIFD--KGVESTNWDCLAKLSLLNDVHLDQNQLVIEHWNINVEFIKEELKTLKSSTQGIILEGFPKDKVQLQQFNIEIGRADLVILLDCDEYYMTTRLLERGERLHRADDDLSNIKKRIIYYKTSGLPVCRYYDERHILNIIPGDRKIAEVLADVISLLELAIMKNRC 1695
I + L+ V L+D E+ CQQ LV+R + W D+ P+AI RI +K TLP+CK D KL+++DG+ E + D+ GK+ S+ + T+ + + PG V +I I + R LP CPI++L GGPG G++ A +C + H NV + +R R+ D +G +WD +A+ +D + +++++ E+WN+ V+ +++E T+ +T+ +++EGFP D+ QL FN IG ADL ILLDC+E + RLL+R RL R +D+ + RI+++K LPV R+YDER L IP DR VL DV++++E + K C
Sbjct: 210 INLENLACVFLIDATEEYCQQQLVERGQSDDYWKDYLPAAITNRICMFKLQTLPMCKAIDVDGKLRVVDGEIKPEHIARDMRTVCEYVLSGKV-TGPSSKPTPGSVPDRPMTKIGHGMVGCPGQPPVFNIPRITPAFADNGRVEGLPTCPIILLFGGPGSGRSEQARALCEKLPGLKHFNVTEFLRNRVLDHIEGDSQKDWDVVARRVHSSDPPMPKDRIIPEYWNVQVDILRQEFNTVAENTKAVVIEGFPNDETQLNIFNQHIGGADLAILLDCEENTLQKRLLKRYTRLSRTEDEETVALHRILFFKHCTLPVIRHYDERSTLVTIPADRDQELVLNDVVTVVEYFLGKQEC 563 HSP 2 Score: 189.119 bits (479), Expect = 3.041e-103 Identity = 84/202 (41.58%), Postives = 135/202 (66.83%), Query Frame = 2
Query: 74 TPRNAKDYLAKNEIPQLFECLMTGLMYHRPLSHIDYLQQCLDRIKKQGVNGVRWDMFLEAKSIPLPPISPSCKEEFTAEGVTDS--NTIQLNISYDVALVIFIAGPGMDKKGLANILTKNYPRFYHVELGRLLREKAETEISKGISKWKVAASLMHCGELAPNDMVLETLIKELNYHTDVSGYIIEGYPRNLEQMQDFEKFV 673
+P K+YL+KN IPQLFECLMTGLMYHRP +++YLQ+CL+++K++GV VRWD+FLE ++ P PP+ + V S +++++ I + +++ + GPG++K + L +YP F H+ +G+LLR +A+ E + SKW + ++ GEL P +MV+E+LI LN H D SG+II+G+PR +Q ++F+ +
Sbjct: 9 SPAETKEYLSKNGIPQLFECLMTGLMYHRPTDYLNYLQECLEKVKRKGVTAVRWDLFLENRTSPPPPVVTKRALNSMSSYVPMSGIDSLKVRIRPNASIICVLGGPGVNKSSYSRGLINHYPTFVHISMGQLLRCRAKLEFERKGSKWTKSVEQINAGELLPQEMVIESLIWHLNQHADASGFIIDGFPRTQQQYEEFKAHI 210 HSP 3 Score: 78.1814 bits (191), Expect = 4.148e-11 Identity = 61/241 (25.31%), Postives = 113/241 (46.89%), Query Frame = 1
Query: 994 PPPGVAQVQDIEEIFNIDP----EIIRPSDLPQCPIVILLGGPGCGKTTAATEICTRYKDWVHINVNDIIRYRI---FDKGVESTNWDCLAKLSLLNDVHLDQNQLVIEH--WNINVEFIKEELKTLKSSTQGIILEGFPKDKVQLQQFNIEIGRADL--VILLDCDEYYMTTRLLERGERLHRADDDL-SNIKKRIIYYKTSGLPVCRYYDERHILNIIPGDRKIAEVLADVISLLELAI 1680
PPP V + + + + P + ++ P I+ +LGGPG K++ + + Y +VHI++ ++R R F++ + + W + +N L ++VIE W++N + G I++GFP+ + Q ++F I +L V L+D E Y +L+ERG+ D L + I RI +K LP+C+ D L ++ G+ K + D+ ++ E +
Sbjct: 72 PPPPVVTKRALNSMSSYVPMSGIDSLKVRIRPNASIICVLGGPGVNKSSYSRGLINHYPTFVHISMGQLLRCRAKLEFER--KGSKW--TKSVEQINAGELLPQEMVIESLIWHLNQH----------ADASGFIIDGFPRTQQQYEEFKAHINLENLACVFLIDATEEYCQQQLVERGQSDDYWKDYLPAAITNRICMFKLQTLPMCKAIDVDGKLRVVDGEIKPEHIARDMRTVCEYVL 298
BLAST of Adenylate kinase isoenzyme 5 vs. TrEMBL
Match: A0A0X3PXV5 (Uncharacterized protein OS=Schistocephalus solidus OX=70667 GN=TR100940 PE=4 SV=1) HSP 1 Score: 203.371 bits (516), Expect = 4.406e-97 Identity = 125/365 (34.25%), Postives = 194/365 (53.15%), Query Frame = 1
Query: 667 ICMNRLSFVILVDCEEDTCQQALVQRPPIEGWTD--HTPSAIGRRIANYKAYTLPVCKYFDDQQKLKMIDGDKTREEVLHDIGKIFKXXXXXXXXXXXXXXXXXXXXYNEIPPPGV---AQVQDIEE-------------IFNIDPEII---RPSDLPQCPIVILLGGPGCGKTTAATEICTRYKDWVHINVNDIIRYRIFDK--GVESTNWDCLAKLSLLNDVHLDQNQLVIEHWNINVEFIKEELKTLKSSTQGIILEGFPKDKVQLQQFNIEIGRADLVILLDCDEYYMTTRLLERGERLHRADDDLSNIKKRIIYYKTSGLPVCRYYDERHILNIIPGDRKIAEVLADVISLLELAIMKNR 1692
+ + RL+ V+L+D E+ C Q L+ + D + S I RR+ N+K TLP+CK DD KL++IDGD + + ++ IF+ LS T+ P PG A V E I I PE R LP+CPI++LLGGPG G+T A +C+ H N+ D++R ++ D G +WD +AK ++ L+ ++L+ E+W+I V+ ++EE L ++ +I+EG+ D+ Q+ FN IG ADL++LLDC+E + RL +RG R+ R +D+ I +RI ++K LPV RY+DE L I+P DR+ V D++ L+E + K R
Sbjct: 210 VGLERLAAVVLIDAPEEKCLQRLMNADQMNDPVDMIQSASVIRRRLCNFKNLTLPMCKTIDDDNKLRVIDGDMKDDHIAREMLTIFEFVLSGKVTGPATR-----------PEPGTIPDAPVNRTMERIVGCVGNPRAFDIARITPEFKDCGRRPHLPKCPILVLLGGPGSGRTKQALALCSMIPGIKHFNITDLLRTKVLDSLVGGAQKDWDVVAKRVHSSEPPLEYDRLIPEYWDIQVDILREEFIKLANTATMVIIEGYLNDESQIITFNQNIGGADLIVLLDCEESTLNQRLSKRGARIRRVEDEGHIINQRINFFKQVTLPVVRYFDELGKLVIVPADREADLVTKDLVYLIEYFLAKGR 563 HSP 2 Score: 183.341 bits (464), Expect = 4.406e-97 Identity = 86/208 (41.35%), Postives = 134/208 (64.42%), Query Frame = 2
Query: 56 DRRCLATPRNAKDYLAKNEIPQLFECLMTGLMYHRPLSHIDYLQQCLDRIKKQGVNGVRWDMFLEAKSIPLPPI-SPSCKEEFTA-EGVTDSNTIQLNISYDVALVIFIAGPGMDKKGLANILTKNYPRFYHVELGRLLREKAETEISKGISKWKVAASLMHCGELAPNDMVLETLIKELNYHTDVSGYIIEGYPRNLEQMQDFEKFV 673
++R + P+ K+YLAK+EIPQLFECLMTGLMYHRP+ + YLQ+C+++IK+QG VRWD+FLE K LPP+ S E F+ E + ++++L + +++ +AGPG+DK G A + +YP F H+ +G L + A E K S+++ A + + G+ AP +M+ E LI LN + +G+I++GYPR +Q +D + V
Sbjct: 3 NKRPIIPPKETKEYLAKHEIPQLFECLMTGLMYHRPVDPLQYLQECIEKIKRQGSQNVRWDLFLETKRSCLPPLTSKRAAEGFSKYEPLPGIDSLRLKMRPQTSVICILAGPGIDKSGFAEKMLTHYPSFIHLNMGDLAKNCARIEERKPSSRFQNAHAFIQAGDFAPEEMIFELLIWNLNQYPASNGFIVDGYPRTFQQYEDLKTHV 210 HSP 3 Score: 69.707 bits (169), Expect = 1.685e-8 Identity = 49/208 (23.56%), Postives = 97/208 (46.63%), Query Frame = 1
Query: 1075 PQCPIVILLGGPGCGKTTAATEICTRYKDWVHINVNDIIR--YRIFDKGVESTNWDCLAKLSLLNDVHLDQNQLVIEHWNINVEFIKEELKTLKSSTQGIILEGFPKDKVQLQQFNIEIG--RADLVILLDCDEYYMTTRLLERGERLHRAD--DDLSNIKKRIIYYKTSGLPVCRYYDERHILNIIPGDRKIAEVLADVISLLELAI 1680
PQ ++ +L GPG K+ A ++ T Y ++H+N+ D+ + RI ++ S + A + D ++ + WN+N ++ G I++G+P+ Q + +G R V+L+D E RL+ + D S I++R+ +K LP+C+ D+ + L +I GD K + +++++ E +
Sbjct: 103 PQTSVICILAGPGIDKSGFAEKMLTHYPSFIHLNMGDLAKNCARIEERKPSSRFQNAHAFIQ-AGDFAPEEMIFELLIWNLNQ----------YPASNGFIVDGYPRTFQQYEDLKTHVGLERLAAVVLIDAPEEKCLQRLMNADQMNDPVDMIQSASVIRRRLCNFKNLTLPMCKTIDDDNKLRVIDGDMKDDHIAREMLTIFEFVL 299
BLAST of Adenylate kinase isoenzyme 5 vs. TrEMBL
Match: A0A4E0RMN6 (Adenylate kinase isoenzyme 5 OS=Fasciola hepatica OX=6192 GN=D915_007311 PE=4 SV=1) HSP 1 Score: 192.971 bits (489), Expect = 8.220e-97 Identity = 89/207 (43.00%), Postives = 140/207 (67.63%), Query Frame = 2
Query: 68 LATPRNAKDYLAKNEIPQLFECLMTGLMYHRPLSHIDYLQQCLDRIKKQGVNGVRWDMFLEAKSIPLPPISPSCKEEFTA--EGVTDSNTIQLNISYDVALVIFIAGPGMDKKGLANILTKNYPRFYHVELGRLLREKAETEISKGISKWKVAASLMHCGELAPNDMVLETLIKELNYHTDVSGYIIEGYPRNLEQMQDFEKFV*ID 682
+ +P K+YL KN +PQLFECLMTGLMYHRP H++YLQ+CL++IKKQG++GVRWD+FLE + PISP E + + + +T+++ I + +++ +AGPG++K + L +YP F H+ +G LLR +A+ E + S+W + ++ GEL P++MV+E+LI LN H+D SG+II+G+PR +Q +D + + +D
Sbjct: 7 VVSPSETKEYLTKNGVPQLFECLMTGLMYHRPADHLNYLQECLEKIKKQGISGVRWDLFLERQHSSPKPISPHKGGENLSKYDPLPGIDTLRVKIRPNTSIICVLAGPGVNKSRYSQGLINHYPTFVHLHMGDLLRNRAKLETQRKSSRWVDSHLKINAGELLPHEMVMESLIWNLNQHSDASGFIIDGFPRTDKQYEDLKSQIGLD 213 HSP 2 Score: 192.971 bits (489), Expect = 8.220e-97 Identity = 123/354 (34.75%), Postives = 188/354 (53.11%), Query Frame = 1
Query: 664 EICMNRLSFVILVDCEEDTCQQALVQRPPI-EGWTDHTPSAIGRRIANYKAYTLPVCKYFDDQQKLKMIDGDKTREEVLHDIGKIFKXXXXXXXXXXXXXXXXXXXXYNEIPP----------PGVAQVQDIEEIFNIDPEIIRPSDLPQCPIVILLGGPGCGKTTAATEICTRYKDWVHINVNDIIRYRIFDKGVEST--NWDCLAKLSLLNDVHLDQNQLVIEHWNINVEFIKEELKTLKSSTQGIILEGFPKDKVQLQQFNIEIGRADLVILLDCDEYYMTTRLLERGERLHRADDDLSNIKKRIIYYKTSGLPVCRYYDERHILNIIPGDRKIAEVLADVISLLELAIMK 1686
+I ++ L+ V L+D E+ C+ L +R E W D+TP AI RI +K TLPVCK D+ KL++IDG+ E + D+ + + LS ++ + PP PG V +I I P+ R +DL CP+++L GGPG G+T A +C R H NV D +R R+ E + +WD +A+ +D + V+ I++E + + + ++ +++EGFP D+ QL FN IG ADL ILLDC+E + RLL R RL R +D+ +RI+++K LPV R+YDER IL IPGDR+ VL D+++++E + K
Sbjct: 209 QIGLDSLACVFLIDAAEEFCKFQLKERGQQDEFWKDNTPDAIDNRICLFKLQTLPVCKCIDNDGKLRVIDGEIKPEHIARDMLTVCEFVLSGKVTGPTSRPTPGSIP--DRPPDRVSHGMTGCPGQPPVFNIPRIVPQFPDKGRVADLYTCPVILLFGGPGSGRTEQAQALCGRLAGLKHFNVTDFLRQRVLYHIEEDSAKDWDVVARRVHSSDP--------PNKRDTQVDIIRQEFEGVANKSRAVVIEGFPNDENQLNTFNQHIGGADLAILLDCEESTLQKRLLSRYTRLGRMEDEDMVSLQRILFFKNCTLPVVRHYDERSILVTIPGDRERDLVLNDLVTVVEYFLSK 552 HSP 3 Score: 78.5666 bits (192), Expect = 3.578e-11 Identity = 58/209 (27.75%), Postives = 100/209 (47.85%), Query Frame = 1
Query: 1075 PQCPIVILLGGPGCGKTTAATEICTRYKDWVHINVNDIIRYRI-FDKGVESTNW-DCLAKLSLLNDVHLDQNQLVIEH--WNINVEFIKEELKTLKSSTQGIILEGFPKDKVQLQQFNIEIGRADL--VILLDCDEYYMTTRLLERGERLHRADDDLSN-IKKRIIYYKTSGLPVCRYYDERHILNIIPGDRKIAEVLADVISLLELAI 1680
P I+ +L GPG K+ + + Y +VH+++ D++R R + +S+ W D K +N L +++V+E WN+N S G I++GFP+ Q + +IG L V L+D E + +L ERG++ D+ + I RI +K LPVC+ D L +I G+ K + D++++ E +
Sbjct: 103 PNTSIICVLAGPGVNKSRYSQGLINHYPTFVHLHMGDLLRNRAKLETQRKSSRWVDSHLK---INAGELLPHEMVMESLIWNLNQH----------SDASGFIIDGFPRTDKQYEDLKSQIGLDSLACVFLIDAAEEFCKFQLKERGQQDEFWKDNTPDAIDNRICLFKLQTLPVCKCIDNDGKLRVIDGEIKPEHIARDMLTVCEFVL 298
BLAST of Adenylate kinase isoenzyme 5 vs. TrEMBL
Match: A0A1S8WYE3 (Uncharacterized protein OS=Opisthorchis viverrini OX=6198 GN=X801_04881 PE=4 SV=1) HSP 1 Score: 222.631 bits (566), Expect = 1.386e-95 Identity = 124/355 (34.93%), Postives = 197/355 (55.49%), Query Frame = 1
Query: 667 ICMNRLSFVILVDCEEDTCQQALVQRPPIEG-WTDHTPSAIGRRIANYKAYTLPVCKYFDDQQKLKMIDGDKTREEVLHDI---------GKIFKXXXXXXXXXXXXXXXXXXXXYNEIPPPGVAQVQDIEEIFNIDPEIIRPSDLPQCPIVILLGGPGCGKTTAATEICTRYKDWVHINVNDIIRYRIFD--KGVESTNWDCLAKLSLLNDVHLDQNQLVIEHWNINVEFIKEELKTLKSSTQGIILEGFPKDKVQLQQFNIEIGRADLVILLDCDEYYMTTRLLERGERLHRADDDLSNIKKRIIYYKTSGLPVCRYYDERHILNIIPGDRKIAEVLADVISLLELAIMKNRC 1695
I + L+ + L+D E+ CQQ LV+R + W D+ P+AI RI +K TLP+CK D KL+++DG+ E + D+ GK+ S+ + T+ + + PG V +I I + R DLP CPI++L GGPG G++ A +C R H NV + +R R+ D +G +WD +A+ +D + +++++ E+WN+ V+ +++E T+ +T+ +++EGFP D+ QL FN IG ADL +LLDC+E + RLL+R RL R +D+ + RI+++K LPV R+YDER L IP DR VL DV++++E + K C
Sbjct: 193 INLENLACIFLIDATEEYCQQQLVERGQSDDYWKDYLPAAIANRICMFKLQTLPMCKTIDADGKLRVVDGEIKPEHIARDMRTVCEYVLSGKV-TGPSSKPTPGSVPDRPMTKIGHGMMGCPGQPPVFNIPRIVPAFADNGRVEDLPTCPIILLFGGPGSGRSEQARALCERLPGLKHFNVTEFLRNRVLDHIEGDSQKDWDVVARRVHSSDPPMPKDRIIPEYWNVQVDILRQEFNTVAENTKAVVIEGFPNDETQLNIFNQHIGGADLAVLLDCEENTLQKRLLKRYTRLSRTEDEETVALHRILFFKHCTLPVIRHYDERSTLVTIPADRDQELVLNDVVTVVEYFLGKQEC 546 HSP 2 Score: 159.073 bits (401), Expect = 1.386e-95 Identity = 72/193 (37.31%), Postives = 120/193 (62.18%), Query Frame = 2
Query: 137 MTGLMYHRPLSHIDYLQQCLDRIKKQGVNGVRWDMFLEAKSIPLPPIS-------PSCKEEFTAEGVTDS-------NTIQLNISYDVALVIFIAGPGMDKKGLANILTKNYPRFYHVELGRLLREKAETEISKGISKWKVAASLMHCGELAPNDMVLETLIKELNYHTDVSGYIIEGYPRNLEQMQDFEKFV 673
MTGLMYHRP +++YLQ+CL+++K++GV VRWD+FLE ++ P PP+ P+ +A S +++++ I + +++ + GPG++K + L +YP F H+ +G LLR +A+ E+ + SKW + ++ GEL P DMV+E+LI LN H D SG+II+G+PR +Q ++F+ +
Sbjct: 1 MTGLMYHRPTDYLNYLQECLEKVKRKGVTEVRWDLFLENRTSPPPPVVTKRGMTIPTANANSSALNSMSSYMPLPGIDSLKVRIRPNASIICVLGGPGVNKSSYSQGLINHYPTFVHISMGHLLRCRAKLEVERKGSKWTKSVEQINAGELLPQDMVIESLIWHLNQHADASGFIIDGFPRTQQQYEEFKAHI 193 HSP 3 Score: 77.0258 bits (188), Expect = 8.712e-11 Identity = 55/207 (26.57%), Postives = 96/207 (46.38%), Query Frame = 1
Query: 1075 PQCPIVILLGGPGCGKTTAATEICTRYKDWVHINVNDIIRYRIFDKGVESTNWDCLAKLSLLNDVHLDQNQLVIEH--WNINVEFIKEELKTLKSSTQGIILEGFPKDKVQLQQFNIEIGRADL--VILLDCDEYYMTTRLLERGERLHRADDDL-SNIKKRIIYYKTSGLPVCRYYDERHILNIIPGDRKIAEVLADVISLLELAI 1680
P I+ +LGGPG K++ + + Y +VHI++ ++R R VE + +N L +VIE W++N + G I++GFP+ + Q ++F I +L + L+D E Y +L+ERG+ D L + I RI +K LP+C+ D L ++ G+ K + D+ ++ E +
Sbjct: 86 PNASIICVLGGPGVNKSSYSQGLINHYPTFVHISMGHLLRCRA-KLEVERKGSKWTKSVEQINAGELLPQDMVIESLIWHLNQH----------ADASGFIIDGFPRTQQQYEEFKAHINLENLACIFLIDATEEYCQQQLVERGQSDDYWKDYLPAAIANRICMFKLQTLPMCKTIDADGKLRVVDGEIKPEHIARDMRTVCEYVL 281
BLAST of Adenylate kinase isoenzyme 5 vs. Ensembl Cavefish
Match: ak5 (adenylate kinase 5 [Source:NCBI gene;Acc:103029093]) HSP 1 Score: 112.464 bits (280), Expect = 1.653e-42 Identity = 78/237 (32.91%), Postives = 121/237 (51.05%), Query Frame = 2
Query: 83 NAKDYLAKNEIPQLFECLMTGLMYHRPLSHIDYLQQCLDRIKK-QGVNGVRWDMFL--EAKSIP-----------------------------LPPISPSCKEEFTAEGVTD-SNTIQLNISYDV--------ALVIFIAGPGMDKKGLANILTKNYPRFYHVELGRLLREKAETEISKGIS--KWKVAASLMHCGELAPNDMVLETLIKELNYHTDVSGYIIEGYPRNLEQMQDFE 664
+AK+YL++ EIPQLFE L+TGLMY+RP IDYL+ CL ++++ G VRWD F+ E KS+P LPPI +F+ E +D S T +L Y+V +++ I GPG K + + + Y F +V +G LLR++ I S KW + A ++ GELAP + + + +++ D +G +I+G+PR++ Q FE
Sbjct: 5 DAKEYLSRREIPQLFESLLTGLMYYRPDDPIDYLECCLKKVRELGGTEKVRWDTFVGQEKKSLPPLNGGQSRRSFFRNVLPDSPNFPYRRYDRLPPI-----HQFSIESDSDLSETAELIEEYEVFDPSRPRPKVILIIGGPGSGKGTQSLKIAERYG-FEYVSVGELLRKRM---IHNATSNRKWSLIAKIITNGELAPQETTITEIKQKIMKIPDANGIVIDGFPRDVGQALSFE 232 HSP 2 Score: 81.2629 bits (199), Expect = 1.653e-42 Identity = 79/350 (22.57%), Postives = 158/350 (45.14%), Query Frame = 1
Query: 664 EICMNRLSFVILVDCEEDTCQQALVQRPPIEGWTDHTPSAIGRRIANYKAYTLPVCKYFDDQQKLKMIDGDKTREEVLHDIG-----KIFKXXXXXXXXXX--------XXXXXXXXXXYNEIPPPGVAQVQDIEEIFNIDPEIIRPSDLPQCPIVILLGGPGCGKTTAATEICTRYKDWVHINVNDIIRYRIFDKGVESTNWDCLAKLSLLNDVHLDQNQLVIEHWNINVEFIKEELKTLKSSTQGIILEGFPKDKVQLQQFNIEIGRADLVILLDCDEYYMTTRLLERG-ERLHRADDDLSNIKKRIIYYKTSGLPVCRYYDERHILNIIPGDRKIAEVLADVISLLE 1671
+IC L V+ + C ++ L +R +G D P A RR+AN+K +P+ KYF ++ + +D D+ EEV +DI K+F + E T + K+ E V + EE F++ E +P ++ ++GGPG GK +I +Y + + I ++S + + DV L++ + + E + ++ + E +++ +G ++ GFP+D Q +++ ++G+ +V+LL+C M+ RL +R L + + +R+ + ++ PV +Y+ + +L+ I ++ EV + L+
Sbjct: 234 QICTPDL--VVFLACSNQRLKERLEKRAEQQGRPDDNPKATERRLANFKQNAVPLVKYFQEKGLIVTLDADRDEEEVFYDISMTVDNKLFPTKEPVAGPSELDLSLLGDNTSVADVPCKFEEQAAEEVGFTEQSEESFSV--EKKKPK------VIFVIGGPGSGKALQCEKIEEQY------GLKRLCPRDILCSELQSHS----ERGRFFRDV-LERGEQLPE--DTLLDLLCESMESTVRHGKGFLVSGFPRDLRQAEEYEAKMGKPCVVLLLECCSDTMSRRLQQRTCSSLRSREARDRDAHRRVDSFCSTITPVIHHYEHKGVLHKIDAEQPPDEVFEQICLALD 560 HSP 3 Score: 99.7525 bits (247), Expect = 1.576e-21 Identity = 59/211 (27.96%), Postives = 108/211 (51.18%), Query Frame = 1
Query: 1024 IEEIFNIDPEIIRPSDLPQCPIVILLGGPGCGKTTAATEICTRYKDWVHINVNDIIRYRIFDKGVESTNWDCLAKLSLLNDVHLDQNQLVIEHWNINVEFIKEELKTLKSSTQGIILEGFPKDKVQLQQFNIEIGRADLVILLDCDEYYMTTRLLERGERLHRADDDLSNIKKRIIYYKTSGLPVCRYYDERHILNIIPGDRKIAEVLADV 1656
IEE DP RP +++++GGPG GK T + +I RY + +++V +++R R+ + W +AK+ + N Q + E IK+++ + + GI+++GFP+D Q F +I DLV+ L C + RL +R E+ R DD+ ++R+ +K + +P+ +Y+ E+ ++ + DR EV D+
Sbjct: 119 IEEYEVFDPSRPRPK------VILIIGGPGSGKGTQSLKIAERY-GFEYVSVGELLRKRMIHNATSNRKWSLIAKI-ITNGELAPQETTITE--------IKQKIMKIPDAN-GIVIDGFPRDVGQALSFEDQICTPDLVVFLACSNQRLKERLEKRAEQQGRPDDNPKATERRLANFKQNAVPLVKYFQEKGLIVTLDADRDEEEVFYDI 312
BLAST of Adenylate kinase isoenzyme 5 vs. Ensembl Cavefish
Match: ak5 (adenylate kinase 5 [Source:NCBI gene;Acc:103029093]) HSP 1 Score: 112.464 bits (280), Expect = 1.653e-42 Identity = 78/237 (32.91%), Postives = 121/237 (51.05%), Query Frame = 2
Query: 83 NAKDYLAKNEIPQLFECLMTGLMYHRPLSHIDYLQQCLDRIKK-QGVNGVRWDMFL--EAKSIP-----------------------------LPPISPSCKEEFTAEGVTD-SNTIQLNISYDV--------ALVIFIAGPGMDKKGLANILTKNYPRFYHVELGRLLREKAETEISKGIS--KWKVAASLMHCGELAPNDMVLETLIKELNYHTDVSGYIIEGYPRNLEQMQDFE 664
+AK+YL++ EIPQLFE L+TGLMY+RP IDYL+ CL ++++ G VRWD F+ E KS+P LPPI +F+ E +D S T +L Y+V +++ I GPG K + + + Y F +V +G LLR++ I S KW + A ++ GELAP + + + +++ D +G +I+G+PR++ Q FE
Sbjct: 5 DAKEYLSRREIPQLFESLLTGLMYYRPDDPIDYLECCLKKVRELGGTEKVRWDTFVGQEKKSLPPLNGGQSRRSFFRNVLPDSPNFPYRRYDRLPPI-----HQFSIESDSDLSETAELIEEYEVFDPSRPRPKVILIIGGPGSGKGTQSLKIAERYG-FEYVSVGELLRKRM---IHNATSNRKWSLIAKIITNGELAPQETTITEIKQKIMKIPDANGIVIDGFPRDVGQALSFE 232 HSP 2 Score: 81.2629 bits (199), Expect = 1.653e-42 Identity = 79/350 (22.57%), Postives = 158/350 (45.14%), Query Frame = 1
Query: 664 EICMNRLSFVILVDCEEDTCQQALVQRPPIEGWTDHTPSAIGRRIANYKAYTLPVCKYFDDQQKLKMIDGDKTREEVLHDIG-----KIFKXXXXXXXXXX--------XXXXXXXXXXYNEIPPPGVAQVQDIEEIFNIDPEIIRPSDLPQCPIVILLGGPGCGKTTAATEICTRYKDWVHINVNDIIRYRIFDKGVESTNWDCLAKLSLLNDVHLDQNQLVIEHWNINVEFIKEELKTLKSSTQGIILEGFPKDKVQLQQFNIEIGRADLVILLDCDEYYMTTRLLERG-ERLHRADDDLSNIKKRIIYYKTSGLPVCRYYDERHILNIIPGDRKIAEVLADVISLLE 1671
+IC L V+ + C ++ L +R +G D P A RR+AN+K +P+ KYF ++ + +D D+ EEV +DI K+F + E T + K+ E V + EE F++ E +P ++ ++GGPG GK +I +Y + + I ++S + + DV L++ + + E + ++ + E +++ +G ++ GFP+D Q +++ ++G+ +V+LL+C M+ RL +R L + + +R+ + ++ PV +Y+ + +L+ I ++ EV + L+
Sbjct: 234 QICTPDL--VVFLACSNQRLKERLEKRAEQQGRPDDNPKATERRLANFKQNAVPLVKYFQEKGLIVTLDADRDEEEVFYDISMTVDNKLFPTKEPVAGPSELDLSLLGDNTSVADVPCKFEEQAAEEVGFTEQSEESFSV--EKKKPK------VIFVIGGPGSGKALQCEKIEEQY------GLKRLCPRDILCSELQSHS----ERGRFFRDV-LERGEQLPE--DTLLDLLCESMESTVRHGKGFLVSGFPRDLRQAEEYEAKMGKPCVVLLLECCSDTMSRRLQQRTCSSLRSREARDRDAHRRVDSFCSTITPVIHHYEHKGVLHKIDAEQPPDEVFEQICLALD 560 HSP 3 Score: 99.7525 bits (247), Expect = 1.576e-21 Identity = 59/211 (27.96%), Postives = 108/211 (51.18%), Query Frame = 1
Query: 1024 IEEIFNIDPEIIRPSDLPQCPIVILLGGPGCGKTTAATEICTRYKDWVHINVNDIIRYRIFDKGVESTNWDCLAKLSLLNDVHLDQNQLVIEHWNINVEFIKEELKTLKSSTQGIILEGFPKDKVQLQQFNIEIGRADLVILLDCDEYYMTTRLLERGERLHRADDDLSNIKKRIIYYKTSGLPVCRYYDERHILNIIPGDRKIAEVLADV 1656
IEE DP RP +++++GGPG GK T + +I RY + +++V +++R R+ + W +AK+ + N Q + E IK+++ + + GI+++GFP+D Q F +I DLV+ L C + RL +R E+ R DD+ ++R+ +K + +P+ +Y+ E+ ++ + DR EV D+
Sbjct: 119 IEEYEVFDPSRPRPK------VILIIGGPGSGKGTQSLKIAERY-GFEYVSVGELLRKRMIHNATSNRKWSLIAKI-ITNGELAPQETTITE--------IKQKIMKIPDAN-GIVIDGFPRDVGQALSFEDQICTPDLVVFLACSNQRLKERLEKRAEQQGRPDDNPKATERRLANFKQNAVPLVKYFQEKGLIVTLDADRDEEEVFYDI 312
BLAST of Adenylate kinase isoenzyme 5 vs. Ensembl Cavefish
Match: ak5 (adenylate kinase 5 [Source:NCBI gene;Acc:103029093]) HSP 1 Score: 112.079 bits (279), Expect = 2.148e-30 Identity = 76/235 (32.34%), Postives = 120/235 (51.06%), Query Frame = 2
Query: 83 NAKDYLAKNEIPQLFECLMTGLMYHRPLSHIDYLQQCLDRIKK-QGVNGVRWDMFL--EAKSIP-----------------------------LPPISPSCKEEFTAEGVTD-SNTIQLNISYDV--------ALVIFIAGPGMDKKGLANILTKNYPRFYHVELGRLLREKAETEISKGISKWKVAASLMHCGELAPNDMVLETLIKELNYHTDVSGYIIEGYPRNLEQMQDFE 664
+AK+YL++ EIPQLFE L+TGLMY+RP IDYL+ CL ++++ G VRWD F+ E KS+P LPPI +F+ E +D S T +L Y+V +++ I GPG K + + + Y F +V +G LLR++ + KW + A ++ GELAP + + + +++ D +G +I+G+PR++ Q FE
Sbjct: 5 DAKEYLSRREIPQLFESLLTGLMYYRPDDPIDYLECCLKKVRELGGTEKVRWDTFVGQEKKSLPPLNGGQSRRSFFRNGMSNSPNFPYRRYDRLPPI-----HQFSIESDSDLSETAELIEEYEVFDPSRPRPKVILIIGGPGSGKGTQSLKIAERYG-FEYVSVGELLRKRMIHNATSN-RKWSLIAKIITNGELAPQETTITEIKQKIMKIPDANGIVIDGFPRDVGQALSFE 232 HSP 2 Score: 40.817 bits (94), Expect = 2.148e-30 Identity = 17/54 (31.48%), Postives = 29/54 (53.70%), Query Frame = 1
Query: 688 FVILVDCEEDTCQQALVQRPPIEGWTDHTPSAIGRRIANYKAYTLPVCKYFDDQ 849
V+ + C ++ L +R +G D P A RR+AN+K +P+ KYF ++
Sbjct: 240 LVVFLACSNQRLKERLEKRAEQQGRPDDNPKATERRLANFKQNAVPLVKYFQEK 293 HSP 3 Score: 93.2041 bits (230), Expect = 1.687e-19 Identity = 56/200 (28.00%), Postives = 104/200 (52.00%), Query Frame = 1
Query: 1024 IEEIFNIDPEIIRPSDLPQCPIVILLGGPGCGKTTAATEICTRYKDWVHINVNDIIRYRIFDKGVESTNWDCLAKLSLLNDVHLDQNQLVIEHWNINVEFIKEELKTLKSSTQGIILEGFPKDKVQLQQFNIEIGRADLVILLDCDEYYMTTRLLERGERLHRADDDLSNIKKRIIYYKTSGLPVCRYYDERH-ILNIIP 1620
IEE DP RP +++++GGPG GK T + +I RY + +++V +++R R+ + W +AK+ + N Q + E IK+++ + + GI+++GFP+D Q F +I DLV+ L C + RL +R E+ R DD+ ++R+ +K + +P+ +Y+ E+ I+ ++P
Sbjct: 119 IEEYEVFDPSRPRPK------VILIIGGPGSGKGTQSLKIAERY-GFEYVSVGELLRKRMIHNATSNRKWSLIAKI-ITNGELAPQETTITE--------IKQKIMKIPDAN-GIVIDGFPRDVGQALSFEDQICTPDLVVFLACSNQRLKERLEKRAEQQGRPDDNPKATERRLANFKQNAVPLVKYFQEKGLIVTLVP 301
BLAST of Adenylate kinase isoenzyme 5 vs. Ensembl Cavefish
Match: ak5l (adenylate kinase isoenzyme 5-like [Source:NCBI gene;Acc:103023903]) HSP 1 Score: 109.768 bits (273), Expect = 4.205e-29 Identity = 69/231 (29.87%), Postives = 110/231 (47.62%), Query Frame = 2
Query: 83 NAKDYLAKNEIPQLFECLMTGLMYHRPLSHIDYLQQCLDRIKK-QGVNGVRWDMFLEAKSIPLPPIS--------------------------PSCKEEFTAEGVTD-SNTIQLNISYDV--------ALVIFIAGPGMDKKGLANILTKNYPRFYHVELGRLLREKAETEISKGISKWKVAASLMHCGELAPNDMVLETLIKELNYHTDVSGYIIEGYPRNLEQMQDFEK 667
+AK+YL+K +IP LFE ++TGLMYHRP + +L+ CL + ++ G V WD F+ PLPPI+ P + +F+ E +D + + L YDV ++ I GPG K + +Y F V +G +LR + + KW++ A ++ GELAP + +E L + D G+I++G+PR + Q FE+
Sbjct: 5 DAKEYLSKTQIPHLFESMLTGLMYHRPEDPLGFLENCLQKTRELGGPESVAWDTFIMPDRKPLPPITSGQGKKAPSKIDSGPGPGPYRRYDRLPPIQAQFSIESDSDMTESSGLIQEYDVFDPSKPRPHIIFVIGGPGSGKGTQTAKIAAHY-DFQCVSVGEILRNQL-LHHAPSDRKWELIAQIIANGELAPQETTIEELKHQFIKKQDAKGFIVDGFPREISQAFTFEE 233 HSP 2 Score: 39.2762 bits (90), Expect = 4.205e-29 Identity = 20/78 (25.64%), Postives = 38/78 (48.72%), Query Frame = 1
Query: 688 FVILVDCEEDTCQQALVQRPPIEGWTDHTPSAIGRRIANYKAYTLPVCKYFDDQQKLKMIDGDKTREEVLHDIGKIFK 921
VIL+ C +Q L +R ++G D AI +R+ +K + KY+ ++ + +D D+ + + DI + K
Sbjct: 240 LVILLACSNQQLRQRLEKRASLQGRPDDNTHAIEKRLETFKHNISLIAKYYQERGLIIRVDADREEDGIFTDIKAVVK 317 HSP 3 Score: 97.4413 bits (241), Expect = 1.303e-21 Identity = 64/229 (27.95%), Postives = 112/229 (48.91%), Query Frame = 1
Query: 1024 IEEIFNIDPEIIRPSDLPQCPIVILLGGPGCGKTTAATEICTRYKDWVHINVNDIIRYRIFDKGVESTNWDCLAKLSLLNDVHLDQNQLVIEHWNINVEFIKEELKTLKSSTQGIILEGFPKDKVQLQQFNIEIGRADLVILLDCDEYYMTTRLLERGERLHRADDDLSNIKKRIIYYKTSGLPVCRYYDERHILNIIPGDRKIAEVLADVISLLELAIMKNRCIDLTP 1710
I+E DP RP I+ ++GGPG GK T +I Y D+ ++V +I+R ++ W+ +A++ + + L + IE + +FIK K +G I++GFP++ Q F +IG DLVILL C + RL +R R DD+ I+KR+ +K + + +YY ER ++ + DR+ + D+ ++++ + N + P
Sbjct: 119 IQEYDVFDPSKPRPH------IIFVIGGPGSGKGTQTAKIAAHY-DFQCVSVGEILRNQLLHHAPSDRKWELIAQI--IANGELAPQETTIE--ELKHQFIK------KQDAKGFIVDGFPREISQAFTFEEQIGSPDLVILLACSNQQLRQRLEKRASLQGRPDDNTHAIEKRLETFKHNISLIAKYYQERGLIIRVDADREEDGIFTDIKAVVKERLFPNELKEEEP 330
BLAST of Adenylate kinase isoenzyme 5 vs. Ensembl Cavefish
Match: ak5l (adenylate kinase isoenzyme 5-like [Source:NCBI gene;Acc:103023903]) HSP 1 Score: 88.1965 bits (217), Expect = 6.931e-23 Identity = 60/218 (27.52%), Postives = 98/218 (44.95%), Query Frame = 2
Query: 122 LFECLMTGLMYHRPLSHIDYLQQCLDRIKK-QGVNGVRWDMFLEAKSIPLPPIS--------------------------PSCKEEFTAEGVTD-SNTIQLNISYDV--------ALVIFIAGPGMDKKGLANILTKNYPRFYHVELGRLLREKAETEISKGISKWKVAASLMHCGELAPNDMVLETLIKELNYHTDVSGYIIEGYPRNLEQMQDFEK 667
L + ++TGLMYHRP + +L+ CL + ++ G V WD F+ PLPPI+ P + +F+ E +D + + L YDV ++ I GPG K + +Y F V +G +LR + + KW++ A ++ GELAP + +E L + D G+I++G+PR + Q FE+
Sbjct: 50 LSQSMLTGLMYHRPEDPLGFLENCLQKTRELGGPESVAWDTFIMPDRKPLPPITSGQGKKAPSKIDSGPGPGPYRRYDRLPPIQAQFSIESDSDMTESSGLIQEYDVFDPSKPRPHIIFVIGGPGSGKGTQTAKIAAHY-DFQCVSVGEILRNQL-LHHAPSDRKWELIAQIIANGELAPQETTIEELKHQFIKKQDAKGFIVDGFPREISQAFTFEE 265 HSP 2 Score: 39.6614 bits (91), Expect = 6.931e-23 Identity = 20/78 (25.64%), Postives = 38/78 (48.72%), Query Frame = 1
Query: 688 FVILVDCEEDTCQQALVQRPPIEGWTDHTPSAIGRRIANYKAYTLPVCKYFDDQQKLKMIDGDKTREEVLHDIGKIFK 921
VIL+ C +Q L +R ++G D AI +R+ +K + KY+ ++ + +D D+ + + DI + K
Sbjct: 272 LVILLACSNQQLRQRLEKRASLQGRPDDNTHAIEKRLETFKHNISLIAKYYQERGLIIRVDADREEDGIFTDIKAVVK 349 HSP 3 Score: 96.2857 bits (238), Expect = 5.436e-21 Identity = 63/222 (28.38%), Postives = 110/222 (49.55%), Query Frame = 1
Query: 1024 IEEIFNIDPEIIRPSDLPQCPIVILLGGPGCGKTTAATEICTRYKDWVHINVNDIIRYRIFDKGVESTNWDCLAKLSLLNDVHLDQNQLVIEHWNINVEFIKEELKTLKSSTQGIILEGFPKDKVQLQQFNIEIGRADLVILLDCDEYYMTTRLLERGERLHRADDDLSNIKKRIIYYKTSGLPVCRYYDERHILNIIPGDRKIAEVLADVISLLELAIMKN 1689
I+E DP RP I+ ++GGPG GK T +I Y D+ ++V +I+R ++ W+ +A++ + + L + IE + +FIK K +G I++GFP++ Q F +IG DLVILL C + RL +R R DD+ I+KR+ +K + + +YY ER ++ + DR+ + D+ ++++ + N
Sbjct: 151 IQEYDVFDPSKPRPH------IIFVIGGPGSGKGTQTAKIAAHY-DFQCVSVGEILRNQLLHHAPSDRKWELIAQI--IANGELAPQETTIE--ELKHQFIK------KQDAKGFIVDGFPREISQAFTFEEQIGSPDLVILLACSNQQLRQRLEKRASLQGRPDDNTHAIEKRLETFKHNISLIAKYYQERGLIIRVDADREEDGIFTDIKAVVKERLFPN 355
BLAST of Adenylate kinase isoenzyme 5 vs. Ensembl Sea Lamprey
Match: ak5l (adenylate kinase 5, like [Source:ZFIN;Acc:ZDB-GENE-050410-2]) HSP 1 Score: 85.5001 bits (210), Expect = 2.257e-19 Identity = 48/190 (25.26%), Postives = 95/190 (50.00%), Query Frame = 1
Query: 1102 GGPGCGKTTAATEICTRYKDWVHINVNDIIRYRIFDKGVESTNWDCLAKLSLLNDVHLDQNQLVIEHWNINVEFIKEELKTLKSSTQGIILEGFPKDKVQLQQFNIEIGRADLVILLDCDEYYMTTRLLERGERLHRADDDLSNIKKRIIYYKTSGLPVCRYYDERHILNIIPGDRKIAEVLADVISLLE 1671
GGPG GK T + ++ Y V +++ +++R + + + W +A++ ++ L + I W + F++ G +++GFP++ Q F ++G D VILL C + RL ER +R R DD+ +++R+ ++ +P+ ++Y ER +L DR+ E+ D+ + +E
Sbjct: 1 GGPGSGKGTQSRKLSESY-GLVCVSLGEVLRQHVLQRAPSNRKWRLIAQI--ISKGELAPQETAI--WELKQHFLQ------NPDAPGFVIDGFPREISQALAFEEQVGAPDAVILLACASERLRQRLGERADRHGRPDDNPRAVERRLATFRQHTVPLVQHYQERGLLLTFDADREEGELFGDIGAAVE 179 HSP 2 Score: 52.7582 bits (125), Expect = 1.428e-16 Identity = 30/99 (30.30%), Postives = 52/99 (52.53%), Query Frame = 2
Query: 377 AGPGMDKKGLANILTKNYPRFYHVELGRLLREKAETEISKGISKWKVAASLMHCGELAPNDMVLETLIKELNYHTDVSGYIIEGYPRNLEQMQDFEKFV 673
GPG K + L+++Y V LG +LR+ + + KW++ A ++ GELAP + + L + + D G++I+G+PR + Q FE+ V
Sbjct: 1 GGPGSGKGTQSRKLSESYG-LVCVSLGEVLRQHV-LQRAPSNRKWRLIAQIISKGELAPQETAIWELKQHFLQNPDAPGFVIDGFPREISQALAFEEQV 97 HSP 3 Score: 51.6026 bits (122), Expect = 1.428e-16 Identity = 23/73 (31.51%), Postives = 41/73 (56.16%), Query Frame = 1
Query: 691 VILVDCEEDTCQQALVQRPPIEGWTDHTPSAIGRRIANYKAYTLPVCKYFDDQQKLKMIDGDKTREEVLHDIG 909
VIL+ C + +Q L +R G D P A+ RR+A ++ +T+P+ +++ ++ L D D+ E+ DIG
Sbjct: 103 VILLACASERLRQRLGERADRHGRPDDNPRAVERRLATFRQHTVPLVQHYQERGLLLTFDADREEGELFGDIG 175
BLAST of Adenylate kinase isoenzyme 5 vs. Ensembl Yeast
Match: URA6 (Uridylate kinase; catalyzes the seventh enzymatic step in the de novo biosynthesis of pyrimidines, converting uridine monophosphate (UMP) into uridine-5'-diphosphate (UDP) [Source:SGD;Acc:S000001507]) HSP 1 Score: 89.7373 bits (221), Expect = 6.814e-21 Identity = 53/194 (27.32%), Postives = 101/194 (52.06%), Query Frame = 1
Query: 1078 QCPIVILLGGPGCGKTTAATEICTRYKDWVHINVNDIIRYRIFDKGVESTNWDCLAKLSLLNDVHLDQNQLVIEHWNINVEFIKEELK-TLKSSTQGIILEGFPKDKVQLQQFNIEIGRADLVILLDCDEYYMTTRLLERGERLHRADDDLSNIKKRIIYYKTSGLPVCRYYDERHILNIIPGDRKIAEVLADV 1656
Q ++ +LGGPG GK T ++ Y +VH++ D++R ++G + + L K + + Q+V + I + ++ + +K++ +++GFP+ Q F +I + ++ DC E M RLLERG+ R+DD++ +IKKR +K + +PV Y++ + + + DR + +V DV
Sbjct: 15 QVSVIFVLGGPGAGKGTQCEKLVKDY-SFVHLSAGDLLRA---EQGRAGSQYGELIKNCI------KEGQIVPQE--ITLALLRNAISDNVKANKHKFLIDGFPRKMDQAISFERDIVESKFILFFDCPEDIMLERLLERGKTSGRSDDNIESIKKRFNTFKETSMPVIEYFETKSKVVRVRCDRSVEDVYKDV 196 HSP 2 Score: 49.2914 bits (116), Expect = 1.926e-14 Identity = 21/73 (28.77%), Postives = 41/73 (56.16%), Query Frame = 1
Query: 688 FVILVDCEEDTCQQALVQRPPIEGWTDHTPSAIGRRIANYKAYTLPVCKYFDDQQKLKMIDGDKTREEVLHDI 906
F++ DC ED + L++R G +D +I +R +K ++PV +YF+ + K+ + D++ E+V D+
Sbjct: 124 FILFFDCPEDIMLERLLERGKTSGRSDDNIESIKKRFNTFKETSMPVIEYFETKSKVVRVRCDRSVEDVYKDV 196 HSP 3 Score: 46.9802 bits (110), Expect = 1.926e-14 Identity = 40/138 (28.99%), Postives = 64/138 (46.38%), Query Frame = 2
Query: 314 VTDSNTIQLNISYDVALVIFI-AGPGMDKKGLANILTKNYPRFYHVELGRLLREKAETEISKGISKWKVAASLMHC---GELAPNDMVLETLIKEL--NYHTDVSGYIIEGYPRNLEQMQDFE------KFV-*IDCP 688
+T + T Q S D VIF+ GPG K L K+Y F H+ G LLR + +G + + + +C G++ P ++ L L + N + ++I+G+PR ++Q FE KF+ DCP
Sbjct: 1 MTAATTSQPAFSPDQVSVIFVLGGPGAGKGTQCEKLVKDYS-FVHLSAGDLLRAE------QGRAGSQYGELIKNCIKEGQIVPQEITLALLRNAISDNVKANKHKFLIDGFPRKMDQAISFERDIVESKFILFFDCP 131
BLAST of Adenylate kinase isoenzyme 5 vs. Ensembl Yeast
Match: ADK1 (Adenylate kinase, required for purine metabolism; localized to the cytoplasm and the mitochondria; lacks cleavable signal sequence; protein abundance increases in response to DNA replication stress; mutations affecting Adk1p catalytic activity deregulate expression of phosphate utilization genes PHO5 and PHO84; human homolog AK1 can complement yeast adk1 mutant [Source:SGD;Acc:S000002634]) HSP 1 Score: 61.2326 bits (147), Expect = 5.690e-11 Identity = 61/224 (27.23%), Postives = 94/224 (41.96%), Query Frame = 1
Query: 1090 VILLGGPGCGKTTAATEICTRYKDWVHINVNDIIRYRIFDKGVESTNWDCLAKLSLLNDVHLDQNQLVIEHWNINVEFIKEELKTLKSSTQGIILEGFPKDKVQ---LQQFNIEIGRA-DLVILLDCDEYYMTTRLLER--------------------------GERL-HRADDDLSNIKKRIIYYKTSGLPVCRYYDERHILNIIPGDRKIAEVLADVISLL 1668
++L+G PG GK T A + R+ H+ D++R +I KG + L L +DQ LV + +I V IK+EL + G IL+GFP+ Q L Q E G + I L D+ + R+ R GE L R+DD+ +KKR+ Y P+ +Y + I + + A V AD+++ L
Sbjct: 9 MVLIGPPGAGKGTQAPNLQERFH-AAHLATGDMLRSQIA-KGTQ---------LGLEAKKIMDQGGLVSD--DIMVNMIKDELTNNPACKNGFILDGFPRTIPQAEKLDQMLKEQGTPLEKAIELKVDDELLVARITGRLIHPASGRSYHKIFNPPKEDMKDDVTGEALVQRSDDNADALKKRLAAYHAQTEPIVDFYKKTGIWAGVDASQPPATVWADILNKL 219
BLAST of Adenylate kinase isoenzyme 5 vs. Ensembl Nematostella
Match: EDO38863 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SBK8]) HSP 1 Score: 62.3882 bits (150), Expect = 1.491e-18 Identity = 31/103 (30.10%), Postives = 59/103 (57.28%), Query Frame = 2
Query: 365 VIFIAGPGMDKKGLANILTKNYPRFYHVELGRLLREKAETEISKGISKWKVAASLMHCGELAPNDMVLETLIKELNYHTDVSGYIIEGYPRNLEQMQDFEKFV 673
+I + GPG K + + + K Y + H+ G LLRE E+++G + ++ +M G+L P ++ + L + H D+ G++I+G+PR+++Q FE+ V
Sbjct: 4 IITLGGPGAGKGTICDSVVKKY-NYCHLSAGDLLRE----EVTRGNERGQMITEMMREGKLVPKEITIGLLQDAMREHKDMPGFLIDGFPRDIDQGITFEEQV 101 HSP 2 Score: 49.2914 bits (116), Expect = 1.491e-18 Identity = 23/77 (29.87%), Postives = 40/77 (51.95%), Query Frame = 1
Query: 688 FVILVDCEEDTCQQALVQRPPIEGWTDHTPSAIGRRIANYKAYTLPVCKYFDDQQKLKMIDGDKTREEVLHDIGKIF 918
FV+ ++C E+ Q+ L++R G D I +R + T+PV ++++ Q K ID + EEV + I +F
Sbjct: 106 FVLYLECTEEVMQERLLKRAETSGRPDDNIETIKKRFVTFLEKTVPVVEHYEKQSKAHRIDASRPLEEVYNAISSLF 182 HSP 3 Score: 83.1889 bits (204), Expect = 2.568e-18 Identity = 56/202 (27.72%), Postives = 106/202 (52.48%), Query Frame = 1
Query: 1090 VILLGGPGCGKTTAATEICTRYKDWVHINVNDIIRYRIFDKGVESTNWDCLAKLSLLNDVHLDQNQLVIEHWNINVEFIKEELKTLKSSTQGIILEGFPKDKVQLQQFNIEIGRADLVILLDCDEYYMTTRLLERGERLHRADDDLSNIKKRIIYYKTSGLPVCRYYDERHILNIIPGDRKIAEVLADVISLL-ELAIMKNR 1692
+I LGGPG GK T + +Y ++ H++ D++R + +G E + ++ ++ + + +LV + I + +++ ++ K G +++GFP+D Q F ++ +D V+ L+C E M RLL+R E R DD++ IKKR + + +PV +Y+++ + I R + EV + SL EL ++ R
Sbjct: 4 IITLGGPGAGKGTICDSVVKKY-NYCHLSAGDLLREEV-TRGNE--------RGQMITEM-MREGKLVPK--EITIGLLQDAMREHKD-MPGFLIDGFPRDIDQGITFEEQVTDSDFVLYLECTEEVMQERLLKRAETSGRPDDNIETIKKRFVTFLEKTVPVVEHYEKQSKAHRIDASRPLEEVYNAISSLFAELPKLERR 191
BLAST of Adenylate kinase isoenzyme 5 vs. Ensembl Nematostella
Match: EDO38864 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SBK9]) HSP 1 Score: 73.559 bits (179), Expect = 3.864e-15 Identity = 50/191 (26.18%), Postives = 89/191 (46.60%), Query Frame = 1
Query: 1099 LGGPGCGKTTAATEICTRYKDWVHINVNDIIRYRIFDKGVESTNWDCLAKLSLLNDVHLDQNQLVIEHWNINVEFIKEELKTLKSSTQGIILEGFPKDKVQLQQFNIEIGRADLVILLDCDEYYMTTRLLERGERLHRADDDLSNIKKRIIYYKTSGLPVCRYYDERHILNIIPGDRKIAEVLADVISLLE 1671
LGGPG GK T I ++ + H + D++R + N ++++ L N +++E + + +K+ +T G +++GFP++ Q +F E+ +L++ +C M RLL+RGE R DD+ I R+ + T +PV +Y E + I + EV V +LE
Sbjct: 1 LGGPGSGKGTQCARIVEKF-GYTHFSTGDLLREEVNSGSERGKNI-----VAMMEKGELVPNGIILEL--LRLAMVKQ------PNTTGFLIDGFPRELEQGLEFEKELALCELLLYFECSPDTMKARLLKRGETSGRVDDNEETILSRLETFITQTMPVIEHYQEEGKVKKISAEGGPDEVFKKVSRVLE 177 HSP 2 Score: 59.3066 bits (142), Expect = 3.099e-10 Identity = 33/98 (33.67%), Postives = 53/98 (54.08%), Query Frame = 2
Query: 374 IAGPGMDKKGLANILTKNYPRFYHVELGRLLREKAETEISKGISKWKVAASLMHCGELAPNDMVLETLIKELNYHTDVSGYIIEGYPRNLEQMQDFEK 667
+ GPG K + + + + H G LLRE E++ G + K ++M GEL PN ++LE L + + +G++I+G+PR LEQ +FEK
Sbjct: 1 LGGPGSGKGTQCARIVEKFG-YTHFSTGDLLRE----EVNSGSERGKNIVAMMEKGELVPNGIILELLRLAMVKQPNTTGFLIDGFPRELEQGLEFEK 93
BLAST of Adenylate kinase isoenzyme 5 vs. Ensembl Nematostella
Match: EDO29897 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RV62]) HSP 1 Score: 64.3142 bits (155), Expect = 6.889e-13 Identity = 26/55 (47.27%), Postives = 43/55 (78.18%), Query Frame = 2
Query: 83 NAKDYLAKNEIPQLFECLMTGLMYHRPLSHIDYLQQCLDRIKKQGVNGVRWDMFL 247
+AK Y+A+ ++ QLFE ++TGL++++P +D+LQQCL ++ K+ NGV+WD FL
Sbjct: 9 DAKGYMARKQVYQLFESMLTGLVHNQPEDPVDFLQQCLQKV-KENRNGVKWDSFL 62
BLAST of Adenylate kinase isoenzyme 5 vs. Ensembl Nematostella
Match: EDO44695 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RV62]) HSP 1 Score: 64.3142 bits (155), Expect = 6.889e-13 Identity = 26/55 (47.27%), Postives = 43/55 (78.18%), Query Frame = 2
Query: 83 NAKDYLAKNEIPQLFECLMTGLMYHRPLSHIDYLQQCLDRIKKQGVNGVRWDMFL 247
+AK Y+A+ ++ QLFE ++TGL++++P +D+LQQCL ++ K+ NGV+WD FL
Sbjct: 9 DAKGYMARKQVYQLFESMLTGLVHNQPEDPVDFLQQCLQKV-KENRNGVKWDSFL 62
BLAST of Adenylate kinase isoenzyme 5 vs. Ensembl Nematostella
Match: EDO36160 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SJH0]) HSP 1 Score: 64.6994 bits (156), Expect = 5.252e-12 Identity = 52/203 (25.62%), Postives = 96/203 (47.29%), Query Frame = 1
Query: 1084 PIVI-LLGGPGCGKTTAATEICTRYKDWVHINVNDIIRYRIFDKGVESTNWDCLAKLSLLNDVHLDQNQLV---IEHWNINVEFIKEELKTLKSSTQGIILEGFPKDKVQLQQFNIEIG-RADL--VILLDCDEYYMTTRLLERGERLHRADDDLSNIKKRIIYYKTSGLPVCRYYDERHILNIIPGDRKIAEVLADVISLLE 1671
P+VI +LGGPG GK T I Y +VH++ +++R + S D L +N + I I V +++ + KS Q +++GFP+++ LQ + + + D+ V+ +C E R++ RG+ R DD++ +++KR ++ S +P+ +Y + ++ I G EV V + E
Sbjct: 7 PVVIFVLGGPGAGKGTQCERIVKEY-GYVHLSAGELLREE---------------RRSGSKDGDLIENCMTEGKIVPVAITVSLLQKAMA--KSDVQKFLIDGFPRNEDNLQGWESRMNDKVDVKAVLFFECPEDICIGRIMSRGQSSGRPDDNIESLRKRFHTHENSTMPIIEHYRRQGLVKPISGAPTPDEVFLQVKRVFE 191 HSP 2 Score: 45.0542 bits (105), Expect = 5.860e-11 Identity = 30/102 (29.41%), Postives = 53/102 (51.96%), Query Frame = 2
Query: 362 LVIFI-AGPGMDKKGLANILTKNYPRFYHVELGRLLREKAETEISKGISKWKVAASLMHCGELAPNDMVLETLIKELNYHTDVSGYIIEGYPRNLEQMQDFE 664
+VIF+ GPG K + K Y + H+ G LLRE E G + + M G++ P + + +L+++ +DV ++I+G+PRN + +Q +E
Sbjct: 8 VVIFVLGGPGAGKGTQCERIVKEYG-YVHLSAGELLRE----ERRSGSKDGDLIENCMTEGKIVPVAITV-SLLQKAMAKSDVQKFLIDGFPRNEDNLQGWE 103 HSP 3 Score: 40.4318 bits (93), Expect = 5.860e-11 Identity = 19/77 (24.68%), Postives = 39/77 (50.65%), Query Frame = 1
Query: 691 VILVDCEEDTCQQALVQRPPIEGWTDHTPSAIGRRIANYKAYTLPVCKYFDDQQKLKMIDGDKTREEVLHDIGKIFK 921
V+ +C ED C ++ R G D ++ +R ++ T+P+ +++ Q +K I G T +EV + ++F+
Sbjct: 115 VLFFECPEDICIGRIMSRGQSSGRPDDNIESLRKRFHTHENSTMPIIEHYRRQGLVKPISGAPTPDEVFLQVKRVFE 191
BLAST of Adenylate kinase isoenzyme 5 vs. Ensembl Medaka
Match: ak5 (adenylate kinase 5 [Source:NCBI gene;Acc:101172192]) HSP 1 Score: 112.464 bits (280), Expect = 5.150e-42 Identity = 77/235 (32.77%), Postives = 120/235 (51.06%), Query Frame = 2
Query: 83 NAKDYLAKNEIPQLFECLMTGLMYHRPLSHIDYLQQCLDRIKK-QGVNGVRWDMFL--EAKSIP-----------------------------LPPISPSCKEEFTAEGVTD-SNTIQLNISYDV--------ALVIFIAGPGMDKKGLANILTKNYPRFYHVELGRLLREKAETEISKGISKWKVAASLMHCGELAPNDMVLETLIKELNYHTDVSGYIIEGYPRNLEQMQDFE 664
+AK+YLA+ EIPQLFE L+TGLMY+RP ID+L+ CL + ++ G VRWD F+ E KS+P LPPIS +F+ E +D S T +L Y+V +++ I GPG K + + + Y F +V +G LLR+K + KW + A ++ GELAP + + + +++ + +G +I+G+PR++ Q FE
Sbjct: 5 DAKEYLARREIPQLFESLLTGLMYYRPDDPIDFLESCLKKARELGGPEKVRWDTFVGQEKKSLPPLNGGQSRRSLFRNVLPESPNFPYRRYDRLPPIS-----QFSIESDSDLSETAELIEEYEVFDPCRPRPKVILVIGGPGSGKGTQSLKIAERYG-FQYVSVGELLRKKMIHNATSN-RKWSLIAKIITNGELAPQETTITEIKQKIMKIPEANGIVIDGFPRDVGQALSFE 232 HSP 2 Score: 79.7221 bits (195), Expect = 5.150e-42 Identity = 76/345 (22.03%), Postives = 141/345 (40.87%), Query Frame = 1
Query: 664 EICMNRLSFVILVDCEEDTCQQALVQRPPIEGWTDHTPSAIGRRIANYKAYTLPVCKYFDDQQKLKMIDGDKTREEVLHDIGKIFKXXXXXXXXXXXXXXXXXXXXYNEIPPPGVAQVQDIEEIFNIDPEIIRPSDLPQC------PIVILLGGPGCGKTTAATEICTRYKDWVHINVNDIIRYRIFDKGVESTN-WDCLAKLSLLNDVHLDQNQLVIEHWNINVEFIKEELKTLKSSTQGIILEGFPKDKVQLQQFNIEIGRADLVILLDCDEYYMTTRLLERGE---RLHRADDDLSNIKKRIIYYKTSGLPVCRYYDERHILNIIPGDRKIAEVLADVISLL 1668
+IC L V+ + C ++ L +R +G D P AI RR+ N+K T+P+ KYF ++ + +D D+ EEV DI +L +E + E +D E + S C ++ ++GGPG GKT + R+ + + D++ + + D L + L +V L +E + + + + +G+++ FP+D Q Q++ ++G VILL C M++R L RG L + D ++ +R + + V YY+ + +L + + EV + ++
Sbjct: 234 QICTPDL--VVFLACANHRLKERLQKRAEQQGRPDDNPKAIDRRLTNFKQNTIPLVKYFQERGLIVTLDADRNEEEVFCDISMTLDNKLFSSKEPAAGPSELDLCLLGEASSLADFVWKDDEVEEEEESVYAEGSAESFCKEQKKPKVIFMMGGPGSGKTLQCERMEERF-GLRRVALGDLLCSELQSHSDRGRHLLDILERGEKLPEVAL-------------LELLCDAVASSARQGKGLVVSSFPRDLSQAQEYEAKMGDPSAVILLTCSPETMSSRSLHRGRSSSSLLASSDTEGSLSRRSESFCSDSQEVTAYYERKKLLYTVDAETSPDEVFLQICQMM 562 HSP 3 Score: 101.293 bits (251), Expect = 5.709e-22 Identity = 61/223 (27.35%), Postives = 114/223 (51.12%), Query Frame = 1
Query: 1024 IEEIFNIDPEIIRPSDLPQCPIVILLGGPGCGKTTAATEICTRYKDWVHINVNDIIRYRIFDKGVESTNWDCLAKLSLLNDVHLDQNQLVIEHWNINVEFIKEELKTLKSSTQGIILEGFPKDKVQLQQFNIEIGRADLVILLDCDEYYMTTRLLERGERLHRADDDLSNIKKRIIYYKTSGLPVCRYYDERHILNIIPGDRKIAEVLADVISLLELAIMKNR 1692
IEE DP RP +++++GGPG GK T + +I RY + +++V +++R ++ + W +AK+ + N Q + E IK+++ + + GI+++GFP+D Q F +I DLV+ L C + + RL +R E+ R DD+ I +R+ +K + +P+ +Y+ ER ++ + DR EV D+ L+ + ++
Sbjct: 119 IEEYEVFDPCRPRPK------VILVIGGPGSGKGTQSLKIAERY-GFQYVSVGELLRKKMIHNATSNRKWSLIAKI-ITNGELAPQETTITE--------IKQKIMKIPEAN-GIVIDGFPRDVGQALSFEDQICTPDLVVFLACANHRLKERLQKRAEQQGRPDDNPKAIDRRLTNFKQNTIPLVKYFQERGLIVTLDADRNEEEVFCDISMTLDNKLFSSK 324
BLAST of Adenylate kinase isoenzyme 5 vs. Ensembl Medaka
Match: ak5 (adenylate kinase 5 [Source:NCBI gene;Acc:101172192]) HSP 1 Score: 83.9593 bits (206), Expect = 1.250e-33 Identity = 64/216 (29.63%), Postives = 103/216 (47.69%), Query Frame = 2
Query: 140 TGLMYHRPLSHIDYLQQCLDRIKK-QGVNGVRWDMFL--EAKSIP-----------------------------LPPISPSCKEEFTAEGVTD-SNTIQLNISYDV--------ALVIFIAGPGMDKKGLANILTKNYPRFYHVELGRLLREKAETEISKGISKWKVAASLMHCGELAPNDMVLETLIKELNYHTDVSGYIIEGYPRNLEQMQDFE 664
TGLMY+RP ID+L+ CL + ++ G VRWD F+ E KS+P LPPIS +F+ E +D S T +L Y+V +++ I GPG K + + + Y F +V +G LLR+K + KW + A ++ GELAP + + + +++ + +G +I+G+PR++ Q FE
Sbjct: 69 TGLMYYRPDDPIDFLESCLKKARELGGPEKVRWDTFVGQEKKSLPPLNGGQSRRSLFRNVLPESPNFPYRRYDRLPPIS-----QFSIESDSDLSETAELIEEYEVFDPCRPRPKVILVIGGPGSGKGTQSLKIAERYG-FQYVSVGELLRKKMIHNATSN-RKWSLIAKIITNGELAPQETTITEIKQKIMKIPEANGIVIDGFPRDVGQALSFE 277 HSP 2 Score: 80.1073 bits (196), Expect = 1.250e-33 Identity = 76/345 (22.03%), Postives = 141/345 (40.87%), Query Frame = 1
Query: 664 EICMNRLSFVILVDCEEDTCQQALVQRPPIEGWTDHTPSAIGRRIANYKAYTLPVCKYFDDQQKLKMIDGDKTREEVLHDIGKIFKXXXXXXXXXXXXXXXXXXXXYNEIPPPGVAQVQDIEEIFNIDPEIIRPSDLPQC------PIVILLGGPGCGKTTAATEICTRYKDWVHINVNDIIRYRIFDKGVESTN-WDCLAKLSLLNDVHLDQNQLVIEHWNINVEFIKEELKTLKSSTQGIILEGFPKDKVQLQQFNIEIGRADLVILLDCDEYYMTTRLLERGE---RLHRADDDLSNIKKRIIYYKTSGLPVCRYYDERHILNIIPGDRKIAEVLADVISLL 1668
+IC L V+ + C ++ L +R +G D P AI RR+ N+K T+P+ KYF ++ + +D D+ EEV DI +L +E + E +D E + S C ++ ++GGPG GKT + R+ + + D++ + + D L + L +V L +E + + + + +G+++ FP+D Q Q++ ++G VILL C M++R L RG L + D ++ +R + + V YY+ + +L + + EV + ++
Sbjct: 279 QICTPDL--VVFLACANHRLKERLQKRAEQQGRPDDNPKAIDRRLTNFKQNTIPLVKYFQERGLIVTLDADRNEEEVFCDISMTLDNKLFSSKEPAAGPSELDLCLLGEASSLADFVWKDDEVEEEEESVYAEGSAESFCKEQKKPKVIFMMGGPGSGKTLQCERMEERF-GLRRVALGDLLCSELQSHSDRGRHLLDILERGEKLPEVAL-------------LELLCDAVASSARQGKGLVVSSFPRDLSQAQEYEAKMGDPSAVILLTCSPETMSSRSLHRGRSSSSLLASSDTEGSLSRRSESFCSDSQEVTAYYERKKLLYTVDAETSPDEVFLQICQMM 607 HSP 3 Score: 101.293 bits (251), Expect = 7.018e-22 Identity = 61/223 (27.35%), Postives = 114/223 (51.12%), Query Frame = 1
Query: 1024 IEEIFNIDPEIIRPSDLPQCPIVILLGGPGCGKTTAATEICTRYKDWVHINVNDIIRYRIFDKGVESTNWDCLAKLSLLNDVHLDQNQLVIEHWNINVEFIKEELKTLKSSTQGIILEGFPKDKVQLQQFNIEIGRADLVILLDCDEYYMTTRLLERGERLHRADDDLSNIKKRIIYYKTSGLPVCRYYDERHILNIIPGDRKIAEVLADVISLLELAIMKNR 1692
IEE DP RP +++++GGPG GK T + +I RY + +++V +++R ++ + W +AK+ + N Q + E IK+++ + + GI+++GFP+D Q F +I DLV+ L C + + RL +R E+ R DD+ I +R+ +K + +P+ +Y+ ER ++ + DR EV D+ L+ + ++
Sbjct: 164 IEEYEVFDPCRPRPK------VILVIGGPGSGKGTQSLKIAERY-GFQYVSVGELLRKKMIHNATSNRKWSLIAKI-ITNGELAPQETTITE--------IKQKIMKIPEAN-GIVIDGFPRDVGQALSFEDQICTPDLVVFLACANHRLKERLQKRAEQQGRPDDNPKAIDRRLTNFKQNTIPLVKYFQERGLIVTLDADRNEEEVFCDISMTLDNKLFSSK 369
BLAST of Adenylate kinase isoenzyme 5 vs. Ensembl Medaka
Match: ak1 (adenylate kinase 1 [Source:NCBI gene;Acc:101156342]) HSP 1 Score: 86.2705 bits (212), Expect = 7.208e-19 Identity = 53/193 (27.46%), Postives = 102/193 (52.85%), Query Frame = 1
Query: 1081 CPIVILLGGPGCGKTTAATEICTRYKDWVHINVNDIIRYRIFDKGVESTNWDCLAKLSLLNDVHLDQNQLVIEHWNINVEFIKEELKTLKSSTQGIILEGFPKDKVQLQQFNIEIGRADLVILLDCDEYYMTTRLLERGERLHRADDDLSNIKKRI-IYYKTSGLPVCRYYDERHILNIIPGDRKIAEVLADV 1656
I+ ++GGPG GK T I +Y + H++ D++R + ++ D +L + + + +LV + ++ IK+ + ++G +++G+P++ Q ++F +IG+ L++ +D M RLL+RGE R+DD+ IKKR+ +YYK + PV +Y+ R I+ + + + EV V
Sbjct: 14 AKIIFVVGGPGSGKGTQCERIVAKY-GYTHLSSGDLLRAEV------ASGSDRGKQLQAI----MQKGELV--PLDTVLDMIKDAMIAKADVSKGFLIDGYPREVKQGEEFEKKIGKPCLLLYVDAKSETMIKRLLKRGETSGRSDDNEETIKKRLDLYYKAT-EPVIAFYESRGIVKKVDSELPVDEVFVQV 192 HSP 2 Score: 63.929 bits (154), Expect = 3.130e-11 Identity = 38/117 (32.48%), Postives = 61/117 (52.14%), Query Frame = 2
Query: 353 DVALVIFIAGPGMDKKGLANILTKNYPRFYHVELGRLLREKAETEISKGISKWKVAASLMHCGELAPNDMVLETLIKELNYHTDVS-GYIIEGYPRNLEQMQDFEKFV*IDCPL*YL 700
D ++ + GPG K + Y + H+ G LLR E++ G + K ++M GEL P D VL+ + + DVS G++I+GYPR ++Q ++FEK + C L Y+
Sbjct: 13 DAKIIFVVGGPGSGKGTQCERIVAKYG-YTHLSSGDLLR----AEVASGSDRGKQLQAIMQKGELVPLDTVLDMIKDAMIAKADVSKGFLIDGYPREVKQGEEFEKKIGKPCLLLYV 124
BLAST of Adenylate kinase isoenzyme 5 vs. Ensembl Medaka
Match: ak1 (adenylate kinase 1 [Source:NCBI gene;Acc:101156342]) HSP 1 Score: 85.8853 bits (211), Expect = 8.212e-19 Identity = 53/193 (27.46%), Postives = 102/193 (52.85%), Query Frame = 1
Query: 1081 CPIVILLGGPGCGKTTAATEICTRYKDWVHINVNDIIRYRIFDKGVESTNWDCLAKLSLLNDVHLDQNQLVIEHWNINVEFIKEELKTLKSSTQGIILEGFPKDKVQLQQFNIEIGRADLVILLDCDEYYMTTRLLERGERLHRADDDLSNIKKRI-IYYKTSGLPVCRYYDERHILNIIPGDRKIAEVLADV 1656
I+ ++GGPG GK T I +Y + H++ D++R + ++ D +L + + + +LV + ++ IK+ + ++G +++G+P++ Q ++F +IG+ L++ +D M RLL+RGE R+DD+ IKKR+ +YYK + PV +Y+ R I+ + + + EV V
Sbjct: 8 AKIIFVVGGPGSGKGTQCERIVAKY-GYTHLSSGDLLRAEV------ASGSDRGKQLQAI----MQKGELV--PLDTVLDMIKDAMIAKADVSKGFLIDGYPREVKQGEEFEKKIGKPCLLLYVDAKSETMIKRLLKRGETSGRSDDNEETIKKRLDLYYKAT-EPVIAFYESRGIVKKVDSELPVDEVFVQV 186 HSP 2 Score: 63.929 bits (154), Expect = 3.299e-11 Identity = 38/117 (32.48%), Postives = 61/117 (52.14%), Query Frame = 2
Query: 353 DVALVIFIAGPGMDKKGLANILTKNYPRFYHVELGRLLREKAETEISKGISKWKVAASLMHCGELAPNDMVLETLIKELNYHTDVS-GYIIEGYPRNLEQMQDFEKFV*IDCPL*YL 700
D ++ + GPG K + Y + H+ G LLR E++ G + K ++M GEL P D VL+ + + DVS G++I+GYPR ++Q ++FEK + C L Y+
Sbjct: 7 DAKIIFVVGGPGSGKGTQCERIVAKYG-YTHLSSGDLLR----AEVASGSDRGKQLQAIMQKGELVPLDTVLDMIKDAMIAKADVSKGFLIDGYPREVKQGEEFEKKIGKPCLLLYV 118
BLAST of Adenylate kinase isoenzyme 5 vs. Ensembl Medaka
Match: ak1 (adenylate kinase 1 [Source:NCBI gene;Acc:101156342]) HSP 1 Score: 85.8853 bits (211), Expect = 9.003e-19 Identity = 53/193 (27.46%), Postives = 102/193 (52.85%), Query Frame = 1
Query: 1081 CPIVILLGGPGCGKTTAATEICTRYKDWVHINVNDIIRYRIFDKGVESTNWDCLAKLSLLNDVHLDQNQLVIEHWNINVEFIKEELKTLKSSTQGIILEGFPKDKVQLQQFNIEIGRADLVILLDCDEYYMTTRLLERGERLHRADDDLSNIKKRI-IYYKTSGLPVCRYYDERHILNIIPGDRKIAEVLADV 1656
I+ ++GGPG GK T I +Y + H++ D++R + ++ D +L + + + +LV + ++ IK+ + ++G +++G+P++ Q ++F +IG+ L++ +D M RLL+RGE R+DD+ IKKR+ +YYK + PV +Y+ R I+ + + + EV V
Sbjct: 8 AKIIFVVGGPGSGKGTQCERIVAKY-GYTHLSSGDLLRAEV------ASGSDRGKQLQAI----MQKGELV--PLDTVLDMIKDAMIAKADVSKGFLIDGYPREVKQGEEFEKKIGKPCLLLYVDAKSETMIKRLLKRGETSGRSDDNEETIKKRLDLYYKAT-EPVIAFYESRGIVKKVDSELPVDEVFVQV 186 HSP 2 Score: 63.929 bits (154), Expect = 2.973e-11 Identity = 38/117 (32.48%), Postives = 61/117 (52.14%), Query Frame = 2
Query: 353 DVALVIFIAGPGMDKKGLANILTKNYPRFYHVELGRLLREKAETEISKGISKWKVAASLMHCGELAPNDMVLETLIKELNYHTDVS-GYIIEGYPRNLEQMQDFEKFV*IDCPL*YL 700
D ++ + GPG K + Y + H+ G LLR E++ G + K ++M GEL P D VL+ + + DVS G++I+GYPR ++Q ++FEK + C L Y+
Sbjct: 7 DAKIIFVVGGPGSGKGTQCERIVAKYG-YTHLSSGDLLR----AEVASGSDRGKQLQAIMQKGELVPLDTVLDMIKDAMIAKADVSKGFLIDGYPREVKQGEEFEKKIGKPCLLLYV 118
BLAST of Adenylate kinase isoenzyme 5 vs. Planmine SMEST
Match: SMESG000024490.1 (SMESG000024490.1) HSP 1 Score: 679.863 bits (1753), Expect = 0.000e+0 Identity = 354/355 (99.72%), Postives = 355/355 (100.00%), Query Frame = 1
Query: 652 AGLREICMNRLSFVILVDCEEDTCQQALVQRPPIEGWTDHTPSAIGRRIANYKAYTLPVCKYFDDQQKLKMIDGDKTREEVLHDIGKIFKXXXXXXXXXXXXXXXXXXXXYNEIPPPGVAQVQDIEEIFNIDPEIIRPSDLPQCPIVILLGGPGCGKTTAATEICTRYKDWVHINVNDIIRYRIFDKGVESTNWDCLAKLSLLNDVHLDQNQLVIEHWNINVEFIKEELKTLKSSTQGIILEGFPKDKVQLQQFNIEIGRADLVILLDCDEYYMTTRLLERGERLHRADDDLSNIKKRIIYYKTSGLPVCRYYDERHILNIIPGDRKIAEVLADVISLLELAIMKNRCIDLTPVL 1716
+GLREICMNRLSFVILVDCEEDTCQQALVQRPPIEGWTDHTPSAIGRRIANYKAYTLPVCKYFDDQQKLKMIDGDKTREEVLHDIGKIFKLELSEFEELEITKIKKTEDKYNEIPPPGVAQVQDIEEIFNIDPEIIRPSDLPQCPIVILLGGPGCGKTTAATEICTRYKDWVHINVNDIIRYRIFDKGVESTNWDCLAKLSLLNDVHLDQNQLVIEHWNINVEFIKEELKTLKSSTQGIILEGFPKDKVQLQQFNIEIGRADLVILLDCDEYYMTTRLLERGERLHRADDDLSNIKKRIIYYKTSGLPVCRYYDERHILNIIPGDRKIAEVLADVISLLELAIMKNRCIDLTPVL
Sbjct: 156 SGLREICMNRLSFVILVDCEEDTCQQALVQRPPIEGWTDHTPSAIGRRIANYKAYTLPVCKYFDDQQKLKMIDGDKTREEVLHDIGKIFKLELSEFEELEITKIKKTEDKYNEIPPPGVAQVQDIEEIFNIDPEIIRPSDLPQCPIVILLGGPGCGKTTAATEICTRYKDWVHINVNDIIRYRIFDKGVESTNWDCLAKLSLLNDVHLDQNQLVIEHWNINVEFIKEELKTLKSSTQGIILEGFPKDKVQLQQFNIEIGRADLVILLDCDEYYMTTRLLERGERLHRADDDLSNIKKRIIYYKTSGLPVCRYYDERHILNIIPGDRKIAEVLADVISLLELAIMKNRCIDLTPVL 510 HSP 2 Score: 309.686 bits (792), Expect = 0.000e+0 Identity = 154/189 (81.48%), Postives = 155/189 (82.01%), Query Frame = 2
Query: 47 MQTDRRCLATPRNAKDYLAKNEIPQLFECLMTGLMYHRPLSHIDYLQQCLDRIKKQGVNGVRWDMFLEAKSIPLPPISPSCKEEFTAEGVTDSNTIQLNISYDVALVIFIAGPGMDKKGLANILTKNYPRFYHVELGRLLREKAETEISKGISKWKVAASLMHCGELAPNDMVLETLIKELNYHTDVSG 613
MQTDRRCLATPRNAKDYLAKNEIPQLFECLMTGLMYHRPLSHIDYLQQCLDRIKKQGVNGVRWDMFLEAKSIPLPPISPSCKEEFTAEGVTDSNTIQLNISYDVALVIFIAGP I+KGISKWKVAASLMHCGELAPNDMVLETLIKELNYHTDVSG
Sbjct: 1 MQTDRRCLATPRNAKDYLAKNEIPQLFECLMTGLMYHRPLSHIDYLQQCLDRIKKQGVNGVRWDMFLEAKSIPLPPISPSCKEEFTAEGVTDSNTIQLNISYDVALVIFIAGPDF--------------------------------ITKGISKWKVAASLMHCGELAPNDMVLETLIKELNYHTDVSG 157
BLAST of Adenylate kinase isoenzyme 5 vs. Planmine SMEST
Match: SMESG000024490.1 (SMESG000024490.1) HSP 1 Score: 667.152 bits (1720), Expect = 0.000e+0 Identity = 349/350 (99.71%), Postives = 349/350 (99.71%), Query Frame = 1
Query: 667 ICMNRLSFVILVDCEEDTCQQALVQRPPIEGWTDHTPSAIGRRIANYKAYTLPVCKYFDDQQKLKMIDGDKTREEVLHDIGKIFKXXXXXXXXXXXXXXXXXXXXYNEIPPPGVAQVQDIEEIFNIDPEIIRPSDLPQCPIVILLGGPGCGKTTAATEICTRYKDWVHINVNDIIRYRIFDKGVESTNWDCLAKLSLLNDVHLDQNQLVIEHWNINVEFIKEELKTLKSSTQGIILEGFPKDKVQLQQFNIEIGRADLVILLDCDEYYMTTRLLERGERLHRADDDLSNIKKRIIYYKTSGLPVCRYYDERHILNIIPGDRKIAEVLADVISLLELAIMKNRCIDLTPVL 1716
I MNRLSFVILVDCEEDTCQQALVQRPPIEGWTDHTPSAIGRRIANYKAYTLPVCKYFDDQQKLKMIDGDKTREEVLHDIGKIFKLELSEFEELEITKIKKTEDKYNEIPPPGVAQVQDIEEIFNIDPEIIRPSDLPQCPIVILLGGPGCGKTTAATEICTRYKDWVHINVNDIIRYRIFDKGVESTNWDCLAKLSLLNDVHLDQNQLVIEHWNINVEFIKEELKTLKSSTQGIILEGFPKDKVQLQQFNIEIGRADLVILLDCDEYYMTTRLLERGERLHRADDDLSNIKKRIIYYKTSGLPVCRYYDERHILNIIPGDRKIAEVLADVISLLELAIMKNRCIDLTPVL
Sbjct: 177 IGMNRLSFVILVDCEEDTCQQALVQRPPIEGWTDHTPSAIGRRIANYKAYTLPVCKYFDDQQKLKMIDGDKTREEVLHDIGKIFKLELSEFEELEITKIKKTEDKYNEIPPPGVAQVQDIEEIFNIDPEIIRPSDLPQCPIVILLGGPGCGKTTAATEICTRYKDWVHINVNDIIRYRIFDKGVESTNWDCLAKLSLLNDVHLDQNQLVIEHWNINVEFIKEELKTLKSSTQGIILEGFPKDKVQLQQFNIEIGRADLVILLDCDEYYMTTRLLERGERLHRADDDLSNIKKRIIYYKTSGLPVCRYYDERHILNIIPGDRKIAEVLADVISLLELAIMKNRCIDLTPVL 526 HSP 2 Score: 351.288 bits (900), Expect = 0.000e+0 Identity = 173/209 (82.78%), Postives = 175/209 (83.73%), Query Frame = 2
Query: 47 MQTDRRCLATPRNAKDYLAKNEIPQLFECLMTGLMYHRPLSHIDYLQQCLDRIKKQGVNGVRWDMFLEAKSIPLPPISPSCKEEFTAEGVTDSNTIQLNISYDVALVIFIAGPGMDKKGLANILTKNYPRFYHVELGRLLREKAETEISKGISKWKVAASLMHCGELAPNDMVLETLIKELNYHTDVSGYIIEGYPRNLEQMQDFEKFV 673
MQTDRRCLATPRNAKDYLAKNEIPQLFECLMTGLMYHRPLSHIDYLQQCLDRIKKQGVNGVRWDMFLEAKSIPLPPISPSCKEEFTAEGVTDSNTIQLNISYDVALVIFIAGP I+KGISKWKVAASLMHCGELAPNDMVLETLIKELNYHTDVSGYIIEGYPRNLEQMQDFEKF+
Sbjct: 1 MQTDRRCLATPRNAKDYLAKNEIPQLFECLMTGLMYHRPLSHIDYLQQCLDRIKKQGVNGVRWDMFLEAKSIPLPPISPSCKEEFTAEGVTDSNTIQLNISYDVALVIFIAGPDF--------------------------------ITKGISKWKVAASLMHCGELAPNDMVLETLIKELNYHTDVSGYIIEGYPRNLEQMQDFEKFI 177 HSP 3 Score: 72.4034 bits (176), Expect = 5.950e-13 Identity = 58/191 (30.37%), Postives = 90/191 (47.12%), Query Frame = 1
Query: 1105 GPGCGKTTAATEICTRYKDWVHINVNDIIRYRIFDKGVES-----TNWDCLAKLSLLNDVHLDQNQLVIEHWNINVEFIKEELKTLKSSTQGIILEGFPKDKVQLQQFNIEIG--RADLVILLDCDEYYMTTRLLERGERLHRADDDLSNIKKRIIYYKTSGLPVCRYYDERHILNIIPGDRKIAEVLADV 1656
P C + A + + + +N++ + IF G + + W A SL++ L N +V+E IKE + G I+EG+P++ Q+Q F IG R VIL+DC+E L++R D S I +RI YK LPVC+Y+D++ L +I GD+ EVL D+
Sbjct: 78 SPSCKEEFTAEGVTD--SNTIQLNISYDVALVIFIAGPDFITKGISKWKVAA--SLMHCGELAPNDMVLE------TLIKE--LNYHTDVSGYIIEGYPRNLEQMQDFEKFIGMNRLSFVILVDCEEDTCQQALVQRPPIEGWTDHTPSAIGRRIANYKAYTLPVCKYFDDQQKLKMIDGDKTREEVLHDI 256
BLAST of Adenylate kinase isoenzyme 5 vs. Planmine SMEST
Match: SMESG000020480.1 (SMESG000020480.1) HSP 1 Score: 259.225 bits (661), Expect = 1.371e-76 Identity = 145/355 (40.85%), Postives = 205/355 (57.75%), Query Frame = 1
Query: 661 REICMNRLSFVILVDCEEDTCQQALVQRPPIEGWTDHTPSAIGRRIANYKAYTLPVCKYFDDQQKLKMIDGDKTREEVLHDIGKIFKXXXXXXXXXXXXXXXXXXXXYNEIPPPGVAQ---------VQDIEEIFNIDPEIIRPSDLPQCPIVILLGGPGCGKTTAATEICTRYKDWVHINVNDIIRYRIFDKGVESTNWDCLAKLSLLNDVHLDQN---QLVIEHWNINVEFIKEELKTLKSSTQGIILEGFPKDKVQLQQFNIEIGRADLVILLDCDEYYMTTRLLERGERLHRADDDLSNIKKRIIYYKTSGLPVCRYYDERHILNIIPGDRKIAEVLADVISLLELAIMKN 1689
R I N+L FVIL+DCEE+ CQQ L+ +PP + W DH+ AI +RIANYK+ TL VCKYFD+ KLK+IDG E D+ ++F E+ E +P + + +I E+ I E R DLPQC +++LLGGPG GKT A ++C RY +WVHI++NDI+R + G+ + A D+N ++E+ +N+ +K+ LK++ Q IILEG+PK+K++L N EIG+ D VILLD +E M RL ER R +D SN + RI Y+KT+GLP+CRYYDER LNI+ DR IA V+ ++ S+ ++KN
Sbjct: 57 RLIGFNKLKFVILIDCEEEVCQQFLLSKPPNKEWKDHSNLAISKRIANYKSNTLAVCKYFDELGKLKIIDGGNESELAYRDVYQLFNKEIHEVHSTCKDLKVDDA----NVPESSIQNDEILEKERTIDEIPELTGIAIETARKDDLPQCTLILLLGGPGSGKTETAIQLCKRYPNWVHIDMNDILRRCMVQNGLSDPDIAQTA----------DENNPESFIVENLIVNINALKKHLKSVDDCAQVIILEGYPKNKIELNDLNTEIGKIDFVILLDSEEDVMKYRLNERWSRFGSKEDIGSNSENRIQYFKTNGLPLCRYYDERCQLNIVNSDRDIAYVIDEIESITS-TLLKN 396
BLAST of Adenylate kinase isoenzyme 5 vs. Planmine SMEST
Match: SMESG000020480.1 (SMESG000020480.1) HSP 1 Score: 259.61 bits (662), Expect = 4.357e-76 Identity = 144/352 (40.91%), Postives = 207/352 (58.81%), Query Frame = 1
Query: 661 REICMNRLSFVILVDCEEDTCQQALVQRPPIEGWTDHTPSAIGRRIANYKAYTLPVCKYFDDQQKLKMIDGDKTREEVLHDIGKIFKXXXXXXXXXXXXXXXXXXXXYNEIPPPGVAQ---------VQDIEEIFNIDPEIIRPSDLPQCPIVILLGGPGCGKTTAATEICTRYKDWVHINVNDIIRYRIFDKGVESTNWDCLAKLSLLNDVHLDQNQLVIEHWNINVEFIKEELKTLKSSTQGIILEGFPKDKVQLQQFNIEIGRADLVILLDCDEYYMTTRLLERGERLHRADDDLSNIKKRIIYYKTSGLPVCRYYDERHILNIIPGDRKIAEVLADVISLLELAIMKN 1689
R I N+L FVIL+DCEE+ CQQ L+ +PP + W DH+ AI +RIANYK+ TL VCKYFD+ KLK+IDG E D+ ++F E+ E +P + + +I E+ I E R DLPQC +++LLGGPG GKT A ++C RY +WVHI++NDI+R + G+ + +A+ + N+ ++E+ +N+ +K+ LK++ Q IILEG+PK+K++L N EIG+ D VILLD +E M RL ER R +D SN + RI Y+KT+GLP+CRYYDER LNI+ DR IA V+ ++ S+ ++KN
Sbjct: 47 RLIGFNKLKFVILIDCEEEVCQQFLLSKPPNKEWKDHSNLAISKRIANYKSNTLAVCKYFDELGKLKIIDGGNESELAYRDVYQLFNKEIHEVHSTCKDLKVDDA----NVPESSIQNDEILEKERTIDEIPELTGIAIETARKDDLPQCTLILLLGGPGSGKTETAIQLCKRYPNWVHIDMNDILRRCMVQNGLSDPD---IAQTADENNPE----SFIVENLIVNINALKKHLKSVDDCAQVIILEGYPKNKIELNDLNTEIGKIDFVILLDSEEDVMKYRLNERWSRFGSKEDIGSNSENRIQYFKTNGLPLCRYYDERCQLNIVNSDRDIAYVIDEIESITS-TLLKN 386
BLAST of Adenylate kinase isoenzyme 5 vs. Planmine SMEST
Match: SMESG000020480.1 (SMESG000020480.1) HSP 1 Score: 259.61 bits (662), Expect = 4.841e-76 Identity = 144/352 (40.91%), Postives = 207/352 (58.81%), Query Frame = 1
Query: 661 REICMNRLSFVILVDCEEDTCQQALVQRPPIEGWTDHTPSAIGRRIANYKAYTLPVCKYFDDQQKLKMIDGDKTREEVLHDIGKIFKXXXXXXXXXXXXXXXXXXXXYNEIPPPGVAQ---------VQDIEEIFNIDPEIIRPSDLPQCPIVILLGGPGCGKTTAATEICTRYKDWVHINVNDIIRYRIFDKGVESTNWDCLAKLSLLNDVHLDQNQLVIEHWNINVEFIKEELKTLKSSTQGIILEGFPKDKVQLQQFNIEIGRADLVILLDCDEYYMTTRLLERGERLHRADDDLSNIKKRIIYYKTSGLPVCRYYDERHILNIIPGDRKIAEVLADVISLLELAIMKN 1689
R I N+L FVIL+DCEE+ CQQ L+ +PP + W DH+ AI +RIANYK+ TL VCKYFD+ KLK+IDG E D+ ++F E+ E +P + + +I E+ I E R DLPQC +++LLGGPG GKT A ++C RY +WVHI++NDI+R + G+ + +A+ + N+ ++E+ +N+ +K+ LK++ Q IILEG+PK+K++L N EIG+ D VILLD +E M RL ER R +D SN + RI Y+KT+GLP+CRYYDER LNI+ DR IA V+ ++ S+ ++KN
Sbjct: 57 RLIGFNKLKFVILIDCEEEVCQQFLLSKPPNKEWKDHSNLAISKRIANYKSNTLAVCKYFDELGKLKIIDGGNESELAYRDVYQLFNKEIHEVHSTCKDLKVDDA----NVPESSIQNDEILEKERTIDEIPELTGIAIETARKDDLPQCTLILLLGGPGSGKTETAIQLCKRYPNWVHIDMNDILRRCMVQNGLSDPD---IAQTADENNPE----SFIVENLIVNINALKKHLKSVDDCAQVIILEGYPKNKIELNDLNTEIGKIDFVILLDSEEDVMKYRLNERWSRFGSKEDIGSNSENRIQYFKTNGLPLCRYYDERCQLNIVNSDRDIAYVIDEIESITS-TLLKN 396 HSP 2 Score: 45.8246 bits (107), Expect = 4.841e-76 Identity = 19/39 (48.72%), Postives = 29/39 (74.36%), Query Frame = 2
Query: 557 DMVLETLIKELNYHTDVSGYIIEGYPRNLEQMQDFEKFV 673
D VLETLIKELN +++ ++I+GYPR ++ DFE+ +
Sbjct: 21 DFVLETLIKELNNNSEKKSFLIDGYPRTEQERLDFERLI 59 The following BLAST results are available for this feature:
BLAST of Adenylate kinase isoenzyme 5 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of Adenylate kinase isoenzyme 5 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of Adenylate kinase isoenzyme 5 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of Adenylate kinase isoenzyme 5 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of Adenylate kinase isoenzyme 5 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of Adenylate kinase isoenzyme 5 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of Adenylate kinase isoenzyme 5 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of Adenylate kinase isoenzyme 5 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Adenylate kinase isoenzyme 5 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of Adenylate kinase isoenzyme 5 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 1
BLAST of Adenylate kinase isoenzyme 5 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 2
BLAST of Adenylate kinase isoenzyme 5 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of Adenylate kinase isoenzyme 5 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of Adenylate kinase isoenzyme 5 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30028060 ID=SMED30028060|Name=Adenylate kinase isoenzyme 5|organism=Schmidtea mediterranea sexual|type=transcript|length=2149bpback to top protein sequence of SMED30028060-orf-1 >SMED30028060-orf-1 ID=SMED30028060-orf-1|Name=SMED30028060-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=210bp MQTDRRCLATPRNAKDYLAKNEIPQLFECLMTGLMYHRPLSHIDYLQQCLback to top protein sequence of SMED30028060-orf-2 >SMED30028060-orf-2 ID=SMED30028060-orf-2|Name=SMED30028060-orf-2|organism=Schmidtea mediterranea sexual|type=polypeptide|length=349bp MNRLSFVILVDCEEDTCQQALVQRPPIEGWTDHTPSAIGRRIANYKAYTLback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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