Abl interactor 2
Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30028026 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 10
Homology
BLAST of Abl interactor 2 vs. Ensembl Human
Match: ABI2 (abl interactor 2 [Source:HGNC Symbol;Acc:HGNC:24011]) HSP 1 Score: 118.627 bits (296), Expect = 9.032e-28 Identity = 64/151 (42.38%), Postives = 93/151 (61.59%), Query Frame = 1 Query: 58 ILLKEDIPNGTEDLINTSKTLEDVADHCLLTY------DRSLEQTVNYTAQALGSVAYKINLLATNFLEVLDKQNIKLNELQTKVNHLNMQVHIHQEKTARLSIGKYTMPRDPNVLKVSKVIEPLT-EIQGKYKRKEIDFSVLDNVGHGLK 489 +LL+E+IP G L ++ LE VAD+C Y R+LE+T YT Q+L SVAY IN LA N L++LD Q +L +++ +NH++ V IH+EK AR IG T + N + K+I P E +Y RK ID+++LD++GHG+K Sbjct: 6 MLLEEEIPGGRRALFDSYTNLERVADYCENNYIQSADKQRALEETKAYTTQSLASVAYLINTLANNVLQMLDIQASQLRRMESSINHISQTVDIHKEKVARREIGILTT--NKNTSRTHKIIAPANLERPVRYIRKPIDYTILDDIGHGVK 154 HSP 2 Score: 65.855 bits (159), Expect = 1.027e-10 Identity = 25/46 (54.35%), Postives = 37/46 (80.43%), Query Frame = 1 Query: 1336 SQVDDGWAPNQYICKVITLYEYQQNKDDELSFQEGELIYVVKKNND 1473 ++ D WAP Y+ KV+ +Y+Y ++K+DELSFQEG +IYV+KKN+D Sbjct: 441 AEEDPPWAPRSYLEKVVAIYDYTKDKEDELSFQEGAIIYVIKKNDD 486
BLAST of Abl interactor 2 vs. Ensembl Human
Match: ABI2 (abl interactor 2 [Source:HGNC Symbol;Acc:HGNC:24011]) HSP 1 Score: 118.627 bits (296), Expect = 1.037e-27 Identity = 64/151 (42.38%), Postives = 93/151 (61.59%), Query Frame = 1 Query: 58 ILLKEDIPNGTEDLINTSKTLEDVADHCLLTY------DRSLEQTVNYTAQALGSVAYKINLLATNFLEVLDKQNIKLNELQTKVNHLNMQVHIHQEKTARLSIGKYTMPRDPNVLKVSKVIEPLT-EIQGKYKRKEIDFSVLDNVGHGLK 489 +LL+E+IP G L ++ LE VAD+C Y R+LE+T YT Q+L SVAY IN LA N L++LD Q +L +++ +NH++ V IH+EK AR IG T + N + K+I P E +Y RK ID+++LD++GHG+K Sbjct: 6 MLLEEEIPGGRRALFDSYTNLERVADYCENNYIQSADKQRALEETKAYTTQSLASVAYLINTLANNVLQMLDIQASQLRRMESSINHISQTVDIHKEKVARREIGILTT--NKNTSRTHKIIAPANLERPVRYIRKPIDYTILDDIGHGVK 154 HSP 2 Score: 107.842 bits (268), Expect = 4.295e-24 Identity = 42/68 (61.76%), Postives = 58/68 (85.29%), Query Frame = 1 Query: 1336 SQVDDGWAPNQYICKVITLYEYQQNKDDELSFQEGELIYVVKKNNDGWWEGVMNGRTGLFPGNYVQNM 1539 ++ D WAP Y+ KV+ +Y+Y ++K+DELSFQEG +IYV+KKN+DGW+EGVMNG TGLFPGNYV+++ Sbjct: 435 AEEDPPWAPRSYLEKVVAIYDYTKDKEDELSFQEGAIIYVIKKNDDGWYEGVMNGVTGLFPGNYVESI 502
BLAST of Abl interactor 2 vs. Ensembl Human
Match: ABI2 (abl interactor 2 [Source:HGNC Symbol;Acc:HGNC:24011]) HSP 1 Score: 117.857 bits (294), Expect = 1.084e-27 Identity = 64/151 (42.38%), Postives = 93/151 (61.59%), Query Frame = 1 Query: 58 ILLKEDIPNGTEDLINTSKTLEDVADHCLLTY------DRSLEQTVNYTAQALGSVAYKINLLATNFLEVLDKQNIKLNELQTKVNHLNMQVHIHQEKTARLSIGKYTMPRDPNVLKVSKVIEPLT-EIQGKYKRKEIDFSVLDNVGHGLK 489 +LL+E+IP G L ++ LE VAD+C Y R+LE+T YT Q+L SVAY IN LA N L++LD Q +L +++ +NH++ V IH+EK AR IG T + N + K+I P E +Y RK ID+++LD++GHG+K Sbjct: 6 MLLEEEIPGGRRALFDSYTNLERVADYCENNYIQSADKQRALEETKAYTTQSLASVAYLINTLANNVLQMLDIQASQLRRMESSINHISQTVDIHKEKVARREIGILTT--NKNTSRTHKIIAPANLERPVRYIRKPIDYTILDDIGHGVK 154 HSP 2 Score: 107.457 bits (267), Expect = 3.967e-24 Identity = 42/68 (61.76%), Postives = 58/68 (85.29%), Query Frame = 1 Query: 1336 SQVDDGWAPNQYICKVITLYEYQQNKDDELSFQEGELIYVVKKNNDGWWEGVMNGRTGLFPGNYVQNM 1539 ++ D WAP Y+ KV+ +Y+Y ++K+DELSFQEG +IYV+KKN+DGW+EGVMNG TGLFPGNYV+++ Sbjct: 386 AEEDPPWAPRSYLEKVVAIYDYTKDKEDELSFQEGAIIYVIKKNDDGWYEGVMNGVTGLFPGNYVESI 453
BLAST of Abl interactor 2 vs. Ensembl Human
Match: ABI2 (abl interactor 2 [Source:HGNC Symbol;Acc:HGNC:24011]) HSP 1 Score: 118.627 bits (296), Expect = 1.220e-27 Identity = 64/151 (42.38%), Postives = 93/151 (61.59%), Query Frame = 1 Query: 58 ILLKEDIPNGTEDLINTSKTLEDVADHCLLTY------DRSLEQTVNYTAQALGSVAYKINLLATNFLEVLDKQNIKLNELQTKVNHLNMQVHIHQEKTARLSIGKYTMPRDPNVLKVSKVIEPLT-EIQGKYKRKEIDFSVLDNVGHGLK 489 +LL+E+IP G L ++ LE VAD+C Y R+LE+T YT Q+L SVAY IN LA N L++LD Q +L +++ +NH++ V IH+EK AR IG T + N + K+I P E +Y RK ID+++LD++GHG+K Sbjct: 6 MLLEEEIPGGRRALFDSYTNLERVADYCENNYIQSADKQRALEETKAYTTQSLASVAYLINTLANNVLQMLDIQASQLRRMESSINHISQTVDIHKEKVARREIGILTT--NKNTSRTHKIIAPANLERPVRYIRKPIDYTILDDIGHGVK 154 HSP 2 Score: 107.071 bits (266), Expect = 6.428e-24 Identity = 42/68 (61.76%), Postives = 58/68 (85.29%), Query Frame = 1 Query: 1336 SQVDDGWAPNQYICKVITLYEYQQNKDDELSFQEGELIYVVKKNNDGWWEGVMNGRTGLFPGNYVQNM 1539 ++ D WAP Y+ KV+ +Y+Y ++K+DELSFQEG +IYV+KKN+DGW+EGVMNG TGLFPGNYV+++ Sbjct: 441 AEEDPPWAPRSYLEKVVAIYDYTKDKEDELSFQEGAIIYVIKKNDDGWYEGVMNGVTGLFPGNYVESI 508
BLAST of Abl interactor 2 vs. Ensembl Human
Match: ABI2 (abl interactor 2 [Source:HGNC Symbol;Acc:HGNC:24011]) HSP 1 Score: 118.627 bits (296), Expect = 1.220e-27 Identity = 64/151 (42.38%), Postives = 93/151 (61.59%), Query Frame = 1 Query: 58 ILLKEDIPNGTEDLINTSKTLEDVADHCLLTY------DRSLEQTVNYTAQALGSVAYKINLLATNFLEVLDKQNIKLNELQTKVNHLNMQVHIHQEKTARLSIGKYTMPRDPNVLKVSKVIEPLT-EIQGKYKRKEIDFSVLDNVGHGLK 489 +LL+E+IP G L ++ LE VAD+C Y R+LE+T YT Q+L SVAY IN LA N L++LD Q +L +++ +NH++ V IH+EK AR IG T + N + K+I P E +Y RK ID+++LD++GHG+K Sbjct: 6 MLLEEEIPGGRRALFDSYTNLERVADYCENNYIQSADKQRALEETKAYTTQSLASVAYLINTLANNVLQMLDIQASQLRRMESSINHISQTVDIHKEKVARREIGILTT--NKNTSRTHKIIAPANLERPVRYIRKPIDYTILDDIGHGVK 154 HSP 2 Score: 107.071 bits (266), Expect = 6.428e-24 Identity = 42/68 (61.76%), Postives = 58/68 (85.29%), Query Frame = 1 Query: 1336 SQVDDGWAPNQYICKVITLYEYQQNKDDELSFQEGELIYVVKKNNDGWWEGVMNGRTGLFPGNYVQNM 1539 ++ D WAP Y+ KV+ +Y+Y ++K+DELSFQEG +IYV+KKN+DGW+EGVMNG TGLFPGNYV+++ Sbjct: 441 AEEDPPWAPRSYLEKVVAIYDYTKDKEDELSFQEGAIIYVIKKNDDGWYEGVMNGVTGLFPGNYVESI 508
BLAST of Abl interactor 2 vs. Ensembl Celegans
Match: abi-1 (ABl Interactor homolog [Source:UniProtKB/TrEMBL;Acc:Q10929]) HSP 1 Score: 91.6633 bits (226), Expect = 2.434e-19 Identity = 53/150 (35.33%), Postives = 86/150 (57.33%), Query Frame = 1 Query: 61 LLKEDIPNGTEDLINTSKTLEDVADHCLLTYDRS------LEQTVNYTAQALGSVAYKINLLATNFLEVLDKQNIKLNELQTKVNHLNMQVHIHQEKTARLSIGKYTMPRDPNVLKVSKVIEP-LTEIQGKYKRKEIDFSVLDNVGHGLK 489 L++ IP+ L + L+ VA +C Y +S LE++ + QAL SVAY+IN + T+ ++L Q K+N L +V +++ V +H+EK AR IG T + + K K+I P + + + +Y+R IDFSVLD +GHG++ Sbjct: 9 LIERRIPDNRAQLETSHANLQQVAAYCEDNYIQSNNKSAALEESKKFAIQALASVAYQINKMVTDLHDMLALQTDKVNSLTNQVQYVSQVVDVHKEKLARREIGSLTT--NKTLFKQPKIIAPAIPDEKQRYQRTPIDFSVLDGIGHGVR 156 HSP 2 Score: 88.9669 bits (219), Expect = 1.502e-18 Identity = 35/60 (58.33%), Postives = 48/60 (80.00%), Query Frame = 1 Query: 1351 GWAPNQYICKVITLYEYQQNKDDELSFQEGELIYVVKKNNDGWWEGVMNGRTGLFPGNYV 1530 GW PN+Y+ KV LY+Y K+DEL+ +E ++YV+KKN+D W+EGV++G TGLFPGNYV Sbjct: 407 GWMPNEYLEKVRVLYDYDAAKEDELTLRENAIVYVLKKNDDDWYEGVLDGVTGLFPGNYV 466
BLAST of Abl interactor 2 vs. Ensembl Celegans
Match: abi-1 (ABl Interactor homolog [Source:UniProtKB/TrEMBL;Acc:Q10929]) HSP 1 Score: 91.6633 bits (226), Expect = 2.434e-19 Identity = 53/150 (35.33%), Postives = 86/150 (57.33%), Query Frame = 1 Query: 61 LLKEDIPNGTEDLINTSKTLEDVADHCLLTYDRS------LEQTVNYTAQALGSVAYKINLLATNFLEVLDKQNIKLNELQTKVNHLNMQVHIHQEKTARLSIGKYTMPRDPNVLKVSKVIEP-LTEIQGKYKRKEIDFSVLDNVGHGLK 489 L++ IP+ L + L+ VA +C Y +S LE++ + QAL SVAY+IN + T+ ++L Q K+N L +V +++ V +H+EK AR IG T + + K K+I P + + + +Y+R IDFSVLD +GHG++ Sbjct: 9 LIERRIPDNRAQLETSHANLQQVAAYCEDNYIQSNNKSAALEESKKFAIQALASVAYQINKMVTDLHDMLALQTDKVNSLTNQVQYVSQVVDVHKEKLARREIGSLTT--NKTLFKQPKIIAPAIPDEKQRYQRTPIDFSVLDGIGHGVR 156 HSP 2 Score: 88.9669 bits (219), Expect = 1.502e-18 Identity = 35/60 (58.33%), Postives = 48/60 (80.00%), Query Frame = 1 Query: 1351 GWAPNQYICKVITLYEYQQNKDDELSFQEGELIYVVKKNNDGWWEGVMNGRTGLFPGNYV 1530 GW PN+Y+ KV LY+Y K+DEL+ +E ++YV+KKN+D W+EGV++G TGLFPGNYV Sbjct: 407 GWMPNEYLEKVRVLYDYDAAKEDELTLRENAIVYVLKKNDDDWYEGVLDGVTGLFPGNYV 466
BLAST of Abl interactor 2 vs. Ensembl Celegans
Match: hum-1 (Heavy chain, Unconventional Myosin [Source:UniProtKB/TrEMBL;Acc:Q19901]) HSP 1 Score: 60.8474 bits (146), Expect = 2.571e-9 Identity = 26/51 (50.98%), Postives = 35/51 (68.63%), Query Frame = 1 Query: 1381 VITLYEYQQNKDDELSFQEGELIYVVKKNNDGWWEGVMNGRTGLFPGNYVQ 1533 VI +Y Y+ DELSF+ G I ++ K+ GWW+G +N R GLFPGNYV+ Sbjct: 1049 VIAVYPYEAQDVDELSFEAGAEIELMNKDASGWWQGKVNNRVGLFPGNYVK 1099
BLAST of Abl interactor 2 vs. Ensembl Celegans
Match: mlk-1 (Mitogen-activated protein kinase kinase kinase mlk-1 [Source:UniProtKB/Swiss-Prot;Acc:A0A0K3AV08]) HSP 1 Score: 60.077 bits (144), Expect = 3.567e-9 Identity = 32/92 (34.78%), Postives = 50/92 (54.35%), Query Frame = 1 Query: 1336 SQVDDGWAPNQYICKVITLYEYQQNKDDELSFQEGELIYVV--KKNNDGWWEGVMNGRTGLFPGNYVQNMN*SHN*FIIIFYYADNLMIYLA 1605 SQV P + + YEY+ KDDEL+ G +I +V + N DGW+ G +NG+ GLFP NY + + N ++ + D +M+ +A Sbjct: 59 SQVSRESPPIRASKAFVASYEYEAQKDDELNLPLGAIITLVTVETNEDGWYRGELNGKVGLFPSNYAREVTYKDN---LVEFKQDEIMLPVA 147
BLAST of Abl interactor 2 vs. Ensembl Celegans
Match: mlk-1 (Mitogen-activated protein kinase kinase kinase mlk-1 [Source:UniProtKB/Swiss-Prot;Acc:A0A0K3AV08]) HSP 1 Score: 60.077 bits (144), Expect = 4.052e-9 Identity = 32/92 (34.78%), Postives = 50/92 (54.35%), Query Frame = 1 Query: 1336 SQVDDGWAPNQYICKVITLYEYQQNKDDELSFQEGELIYVV--KKNNDGWWEGVMNGRTGLFPGNYVQNMN*SHN*FIIIFYYADNLMIYLA 1605 SQV P + + YEY+ KDDEL+ G +I +V + N DGW+ G +NG+ GLFP NY + + N ++ + D +M+ +A Sbjct: 59 SQVSRESPPIRASKAFVASYEYEAQKDDELNLPLGAIITLVTVETNEDGWYRGELNGKVGLFPSNYAREVTYKDN---LVEFKQDEIMLPVA 147
BLAST of Abl interactor 2 vs. Ensembl Fly
Match: Abi (gene:FBgn0020510 transcript:FBtr0307077) HSP 1 Score: 109.768 bits (273), Expect = 3.457e-25 Identity = 67/170 (39.41%), Postives = 101/170 (59.41%), Query Frame = 1 Query: 10 LNNFSMGTEFLPKDYIILLKEDIPNGTEDLINTSKTLEDVADHCLLTYDRS------LEQTVNYTAQALGSVAYKINLLATNFLEVLDKQNIKLNELQTKVNHLNMQVHIHQEKTARLSIGKYTMPR-DPNVLKVSKVIEPLTEIQGKYKRKEIDFSVLDNVGHGLKEPQ 498 L M +E + + L++ +IP+G + L ++ LE VAD+C TY R+ LE T NYT Q+L SVAY+IN LA +++++L+ Q +L E+++++NH+ VHIH+EK AR IG T + K+ I P I KY RK ID+S+LD +GHG+ Q Sbjct: 2 LTETPMASENIMDELASLIRTEIPDGRQSLRDSYTNLERVADYCEDTYYRADNKKAALEATKNYTTQSLASVAYQINTLAYSYMQLLELQAQQLGEMESQMNHIAQTVHIHKEKVARREIGVLTANKVSSRQFKIVAPINPEKPI--KYVRKPIDYSMLDEIGHGINSAQ 169 HSP 2 Score: 102.064 bits (253), Expect = 1.028e-22 Identity = 40/61 (65.57%), Postives = 51/61 (83.61%), Query Frame = 1 Query: 1351 GWAPNQYICKVITLYEYQQNKDDELSFQEGELIYVVKKNNDGWWEGVMNGRTGLFPGNYVQ 1533 GW P +I KV+ +Y+Y +KDDELSFQE ++YV+KKN+DGWWEGVM+G TGLFPGNYV+ Sbjct: 414 GWVPKNFIEKVVAIYDYYADKDDELSFQESSVLYVLKKNDDGWWEGVMDGVTGLFPGNYVE 474
BLAST of Abl interactor 2 vs. Ensembl Fly
Match: Abi (gene:FBgn0020510 transcript:FBtr0307076) HSP 1 Score: 109.768 bits (273), Expect = 3.465e-25 Identity = 67/170 (39.41%), Postives = 101/170 (59.41%), Query Frame = 1 Query: 10 LNNFSMGTEFLPKDYIILLKEDIPNGTEDLINTSKTLEDVADHCLLTYDRS------LEQTVNYTAQALGSVAYKINLLATNFLEVLDKQNIKLNELQTKVNHLNMQVHIHQEKTARLSIGKYTMPR-DPNVLKVSKVIEPLTEIQGKYKRKEIDFSVLDNVGHGLKEPQ 498 L M +E + + L++ +IP+G + L ++ LE VAD+C TY R+ LE T NYT Q+L SVAY+IN LA +++++L+ Q +L E+++++NH+ VHIH+EK AR IG T + K+ I P I KY RK ID+S+LD +GHG+ Q Sbjct: 2 LTETPMASENIMDELASLIRTEIPDGRQSLRDSYTNLERVADYCEDTYYRADNKKAALEATKNYTTQSLASVAYQINTLAYSYMQLLELQAQQLGEMESQMNHIAQTVHIHKEKVARREIGVLTANKVSSRQFKIVAPINPEKPI--KYVRKPIDYSMLDEIGHGINSAQ 169 HSP 2 Score: 102.064 bits (253), Expect = 1.037e-22 Identity = 40/61 (65.57%), Postives = 51/61 (83.61%), Query Frame = 1 Query: 1351 GWAPNQYICKVITLYEYQQNKDDELSFQEGELIYVVKKNNDGWWEGVMNGRTGLFPGNYVQ 1533 GW P +I KV+ +Y+Y +KDDELSFQE ++YV+KKN+DGWWEGVM+G TGLFPGNYV+ Sbjct: 409 GWVPKNFIEKVVAIYDYYADKDDELSFQESSVLYVLKKNDDGWWEGVMDGVTGLFPGNYVE 469
BLAST of Abl interactor 2 vs. Ensembl Fly
Match: Abi (gene:FBgn0020510 transcript:FBtr0337096) HSP 1 Score: 109.768 bits (273), Expect = 3.465e-25 Identity = 67/170 (39.41%), Postives = 101/170 (59.41%), Query Frame = 1 Query: 10 LNNFSMGTEFLPKDYIILLKEDIPNGTEDLINTSKTLEDVADHCLLTYDRS------LEQTVNYTAQALGSVAYKINLLATNFLEVLDKQNIKLNELQTKVNHLNMQVHIHQEKTARLSIGKYTMPR-DPNVLKVSKVIEPLTEIQGKYKRKEIDFSVLDNVGHGLKEPQ 498 L M +E + + L++ +IP+G + L ++ LE VAD+C TY R+ LE T NYT Q+L SVAY+IN LA +++++L+ Q +L E+++++NH+ VHIH+EK AR IG T + K+ I P I KY RK ID+S+LD +GHG+ Q Sbjct: 2 LTETPMASENIMDELASLIRTEIPDGRQSLRDSYTNLERVADYCEDTYYRADNKKAALEATKNYTTQSLASVAYQINTLAYSYMQLLELQAQQLGEMESQMNHIAQTVHIHKEKVARREIGVLTANKVSSRQFKIVAPINPEKPI--KYVRKPIDYSMLDEIGHGINSAQ 169 HSP 2 Score: 102.064 bits (253), Expect = 1.037e-22 Identity = 40/61 (65.57%), Postives = 51/61 (83.61%), Query Frame = 1 Query: 1351 GWAPNQYICKVITLYEYQQNKDDELSFQEGELIYVVKKNNDGWWEGVMNGRTGLFPGNYVQ 1533 GW P +I KV+ +Y+Y +KDDELSFQE ++YV+KKN+DGWWEGVM+G TGLFPGNYV+ Sbjct: 409 GWVPKNFIEKVVAIYDYYADKDDELSFQESSVLYVLKKNDDGWWEGVMDGVTGLFPGNYVE 469
BLAST of Abl interactor 2 vs. Ensembl Fly
Match: Abi (gene:FBgn0020510 transcript:FBtr0337097) HSP 1 Score: 109.768 bits (273), Expect = 3.496e-25 Identity = 67/170 (39.41%), Postives = 101/170 (59.41%), Query Frame = 1 Query: 10 LNNFSMGTEFLPKDYIILLKEDIPNGTEDLINTSKTLEDVADHCLLTYDRS------LEQTVNYTAQALGSVAYKINLLATNFLEVLDKQNIKLNELQTKVNHLNMQVHIHQEKTARLSIGKYTMPR-DPNVLKVSKVIEPLTEIQGKYKRKEIDFSVLDNVGHGLKEPQ 498 L M +E + + L++ +IP+G + L ++ LE VAD+C TY R+ LE T NYT Q+L SVAY+IN LA +++++L+ Q +L E+++++NH+ VHIH+EK AR IG T + K+ I P I KY RK ID+S+LD +GHG+ Q Sbjct: 2 LTETPMASENIMDELASLIRTEIPDGRQSLRDSYTNLERVADYCEDTYYRADNKKAALEATKNYTTQSLASVAYQINTLAYSYMQLLELQAQQLGEMESQMNHIAQTVHIHKEKVARREIGVLTANKVSSRQFKIVAPINPEKPI--KYVRKPIDYSMLDEIGHGINSAQ 169 HSP 2 Score: 102.064 bits (253), Expect = 1.044e-22 Identity = 40/61 (65.57%), Postives = 51/61 (83.61%), Query Frame = 1 Query: 1351 GWAPNQYICKVITLYEYQQNKDDELSFQEGELIYVVKKNNDGWWEGVMNGRTGLFPGNYVQ 1533 GW P +I KV+ +Y+Y +KDDELSFQE ++YV+KKN+DGWWEGVM+G TGLFPGNYV+ Sbjct: 410 GWVPKNFIEKVVAIYDYYADKDDELSFQESSVLYVLKKNDDGWWEGVMDGVTGLFPGNYVE 470
BLAST of Abl interactor 2 vs. Ensembl Fly
Match: Abi (gene:FBgn0020510 transcript:FBtr0082910) HSP 1 Score: 109.768 bits (273), Expect = 3.496e-25 Identity = 67/170 (39.41%), Postives = 101/170 (59.41%), Query Frame = 1 Query: 10 LNNFSMGTEFLPKDYIILLKEDIPNGTEDLINTSKTLEDVADHCLLTYDRS------LEQTVNYTAQALGSVAYKINLLATNFLEVLDKQNIKLNELQTKVNHLNMQVHIHQEKTARLSIGKYTMPR-DPNVLKVSKVIEPLTEIQGKYKRKEIDFSVLDNVGHGLKEPQ 498 L M +E + + L++ +IP+G + L ++ LE VAD+C TY R+ LE T NYT Q+L SVAY+IN LA +++++L+ Q +L E+++++NH+ VHIH+EK AR IG T + K+ I P I KY RK ID+S+LD +GHG+ Q Sbjct: 2 LTETPMASENIMDELASLIRTEIPDGRQSLRDSYTNLERVADYCEDTYYRADNKKAALEATKNYTTQSLASVAYQINTLAYSYMQLLELQAQQLGEMESQMNHIAQTVHIHKEKVARREIGVLTANKVSSRQFKIVAPINPEKPI--KYVRKPIDYSMLDEIGHGINSAQ 169 HSP 2 Score: 102.064 bits (253), Expect = 1.044e-22 Identity = 40/61 (65.57%), Postives = 51/61 (83.61%), Query Frame = 1 Query: 1351 GWAPNQYICKVITLYEYQQNKDDELSFQEGELIYVVKKNNDGWWEGVMNGRTGLFPGNYVQ 1533 GW P +I KV+ +Y+Y +KDDELSFQE ++YV+KKN+DGWWEGVM+G TGLFPGNYV+ Sbjct: 410 GWVPKNFIEKVVAIYDYYADKDDELSFQESSVLYVLKKNDDGWWEGVMDGVTGLFPGNYVE 470
BLAST of Abl interactor 2 vs. Ensembl Zebrafish
Match: abi2a (abl-interactor 2a [Source:ZFIN;Acc:ZDB-GENE-060929-192]) HSP 1 Score: 116.701 bits (291), Expect = 4.815e-28 Identity = 64/151 (42.38%), Postives = 96/151 (63.58%), Query Frame = 1 Query: 58 ILLKEDIPNGTEDLINTSKTLEDVADHCLLTY----DR--SLEQTVNYTAQALGSVAYKINLLATNFLEVLDKQNIKLNELQTKVNHLNMQVHIHQEKTARLSIGKYTMPRDPNVLKVSKVIEPLT-EIQGKYKRKEIDFSVLDNVGHGLK 489 +LL+E+IP G L+++ L+ VA++C Y D+ +LE+T NYT Q+L SVAY IN LA N L++LD Q +L +++ +NH++ V IH+EK AR IG T + N + K+I P E +Y RK ID+S+LD++GHG+K Sbjct: 6 MLLEEEIPAGRRALLDSFTNLDRVAEYCESNYVQAPDKHVALEETKNYTTQSLASVAYLINTLANNVLQMLDIQASQLRRMESSINHISQTVDIHKEKVARREIGILTT--NKNTSRTHKIIAPANPERPVRYIRKPIDYSMLDDIGHGVK 154
BLAST of Abl interactor 2 vs. Ensembl Zebrafish
Match: abi2b (abl-interactor 2b [Source:ZFIN;Acc:ZDB-GENE-060519-5]) HSP 1 Score: 117.857 bits (294), Expect = 8.836e-28 Identity = 65/151 (43.05%), Postives = 95/151 (62.91%), Query Frame = 1 Query: 58 ILLKEDIPNGTEDLINTSKTLEDVADHCLLTY------DRSLEQTVNYTAQALGSVAYKINLLATNFLEVLDKQNIKLNELQTKVNHLNMQVHIHQEKTARLSIGKYTMPRDPNVLKVSKVIEPLT-EIQGKYKRKEIDFSVLDNVGHGLK 489 +LL+E+IP G L+++ LE VA++C Y R+LE+T +YT Q+L SVAY IN LA N L++LD Q +L +++ +NH++ V IH+EK AR IG T + N + K+I P E +Y RK ID+S+LD+VGHG+K Sbjct: 6 MLLEEEIPAGRGALLDSYANLERVAEYCESNYIQSPDKHRALEETKSYTTQSLASVAYLINTLANNVLQMLDIQASQLRRMESSINHISQTVDIHKEKVARREIGILTT--NKNTSRTHKIIAPANPERPVRYIRKPIDYSLLDDVGHGVK 154 HSP 2 Score: 105.916 bits (263), Expect = 6.791e-24 Identity = 45/83 (54.22%), Postives = 62/83 (74.70%), Query Frame = 1 Query: 1336 SQVDDGWAPNQYICKVITLYEYQQNKDDELSFQEGELIYVVKKNNDGWWEGVMNGRTGLFPGNYVQNMN*SHN*FIIIFYYAD 1584 ++ D WAP Y+ KV+ +Y+Y ++K+DELSFQEG +IYV+KKN+DGW+EGVM+G TGLFPGNYV++ I +YAD Sbjct: 389 AEEDPPWAPRSYLEKVVAIYDYTRDKEDELSFQEGAIIYVIKKNDDGWYEGVMSGTTGLFPGNYVES----------IMHYAD 461
BLAST of Abl interactor 2 vs. Ensembl Zebrafish
Match: abi2b (abl-interactor 2b [Source:ZFIN;Acc:ZDB-GENE-060519-5]) HSP 1 Score: 117.857 bits (294), Expect = 1.112e-27 Identity = 65/151 (43.05%), Postives = 95/151 (62.91%), Query Frame = 1 Query: 58 ILLKEDIPNGTEDLINTSKTLEDVADHCLLTY------DRSLEQTVNYTAQALGSVAYKINLLATNFLEVLDKQNIKLNELQTKVNHLNMQVHIHQEKTARLSIGKYTMPRDPNVLKVSKVIEPLT-EIQGKYKRKEIDFSVLDNVGHGLK 489 +LL+E+IP G L+++ LE VA++C Y R+LE+T +YT Q+L SVAY IN LA N L++LD Q +L +++ +NH++ V IH+EK AR IG T + N + K+I P E +Y RK ID+S+LD+VGHG+K Sbjct: 6 MLLEEEIPAGRGALLDSYANLERVAEYCESNYIQSPDKHRALEETKSYTTQSLASVAYLINTLANNVLQMLDIQASQLRRMESSINHISQTVDIHKEKVARREIGILTT--NKNTSRTHKIIAPANPERPVRYIRKPIDYSLLDDVGHGVK 154 HSP 2 Score: 106.686 bits (265), Expect = 5.588e-24 Identity = 45/83 (54.22%), Postives = 62/83 (74.70%), Query Frame = 1 Query: 1336 SQVDDGWAPNQYICKVITLYEYQQNKDDELSFQEGELIYVVKKNNDGWWEGVMNGRTGLFPGNYVQNMN*SHN*FIIIFYYAD 1584 ++ D WAP Y+ KV+ +Y+Y ++K+DELSFQEG +IYV+KKN+DGW+EGVM+G TGLFPGNYV++ I +YAD Sbjct: 418 AEEDPPWAPRSYLEKVVAIYDYTRDKEDELSFQEGAIIYVIKKNDDGWYEGVMSGTTGLFPGNYVES----------IMHYAD 490
BLAST of Abl interactor 2 vs. Ensembl Zebrafish
Match: abi2a (abl-interactor 2a [Source:ZFIN;Acc:ZDB-GENE-060929-192]) HSP 1 Score: 116.316 bits (290), Expect = 1.155e-27 Identity = 64/151 (42.38%), Postives = 96/151 (63.58%), Query Frame = 1 Query: 58 ILLKEDIPNGTEDLINTSKTLEDVADHCLLTY----DR--SLEQTVNYTAQALGSVAYKINLLATNFLEVLDKQNIKLNELQTKVNHLNMQVHIHQEKTARLSIGKYTMPRDPNVLKVSKVIEPLT-EIQGKYKRKEIDFSVLDNVGHGLK 489 +LL+E+IP G L+++ L+ VA++C Y D+ +LE+T NYT Q+L SVAY IN LA N L++LD Q +L +++ +NH++ V IH+EK AR IG T + N + K+I P E +Y RK ID+S+LD++GHG+K Sbjct: 6 MLLEEEIPAGRRALLDSFTNLDRVAEYCESNYVQAPDKHVALEETKNYTTQSLASVAYLINTLANNVLQMLDIQASQLRRMESSINHISQTVDIHKEKVARREIGILTT--NKNTSRTHKIIAPANPERPVRYIRKPIDYSMLDDIGHGVK 154
BLAST of Abl interactor 2 vs. Ensembl Zebrafish
Match: abi2b (abl-interactor 2b [Source:ZFIN;Acc:ZDB-GENE-060519-5]) HSP 1 Score: 116.701 bits (291), Expect = 1.493e-27 Identity = 65/151 (43.05%), Postives = 95/151 (62.91%), Query Frame = 1 Query: 58 ILLKEDIPNGTEDLINTSKTLEDVADHCLLTY------DRSLEQTVNYTAQALGSVAYKINLLATNFLEVLDKQNIKLNELQTKVNHLNMQVHIHQEKTARLSIGKYTMPRDPNVLKVSKVIEPLT-EIQGKYKRKEIDFSVLDNVGHGLK 489 +LL+E+IP G L+++ LE VA++C Y R+LE+T +YT Q+L SVAY IN LA N L++LD Q +L +++ +NH++ V IH+EK AR IG T + N + K+I P E +Y RK ID+S+LD+VGHG+K Sbjct: 6 MLLEEEIPAGRGALLDSYANLERVAEYCESNYIQSPDKHRALEETKSYTTQSLASVAYLINTLANNVLQMLDIQASQLRRMESSINHISQTVDIHKEKVARREIGILTT--NKNTSRTHKIIAPANPERPVRYIRKPIDYSLLDDVGHGVK 154 HSP 2 Score: 105.145 bits (261), Expect = 1.235e-23 Identity = 45/83 (54.22%), Postives = 62/83 (74.70%), Query Frame = 1 Query: 1336 SQVDDGWAPNQYICKVITLYEYQQNKDDELSFQEGELIYVVKKNNDGWWEGVMNGRTGLFPGNYVQNMN*SHN*FIIIFYYAD 1584 ++ D WAP Y+ KV+ +Y+Y ++K+DELSFQEG +IYV+KKN+DGW+EGVM+G TGLFPGNYV++ I +YAD Sbjct: 375 AEEDPPWAPRSYLEKVVAIYDYTRDKEDELSFQEGAIIYVIKKNDDGWYEGVMSGTTGLFPGNYVES----------IMHYAD 447
BLAST of Abl interactor 2 vs. Ensembl Xenopus
Match: abi2 (abl-interactor 2 [Source:NCBI gene;Acc:548798]) HSP 1 Score: 118.242 bits (295), Expect = 1.325e-27 Identity = 64/151 (42.38%), Postives = 93/151 (61.59%), Query Frame = 1 Query: 58 ILLKEDIPNGTEDLINTSKTLEDVADHCLLTY------DRSLEQTVNYTAQALGSVAYKINLLATNFLEVLDKQNIKLNELQTKVNHLNMQVHIHQEKTARLSIGKYTMPRDPNVLKVSKVIEPLT-EIQGKYKRKEIDFSVLDNVGHGLK 489 +LL+E+IP G L+++ LE VAD+C Y R+LE+T YT Q+L SVAY IN LA N L++LD Q +L +++ +NH++ V IH+EK AR IG T + N + K+I P E +Y RK ID+++LD+ GHG+K Sbjct: 6 MLLEEEIPGGRRALLDSYTNLERVADYCENNYIQSPDKQRALEETKAYTTQSLASVAYLINTLANNVLQMLDIQASQLRRMESSINHISQTVDIHKEKVARREIGILTT--NKNTSRTHKIIAPANLERPVRYIRKPIDYTILDDTGHGVK 154 HSP 2 Score: 107.842 bits (268), Expect = 3.703e-24 Identity = 42/68 (61.76%), Postives = 58/68 (85.29%), Query Frame = 1 Query: 1336 SQVDDGWAPNQYICKVITLYEYQQNKDDELSFQEGELIYVVKKNNDGWWEGVMNGRTGLFPGNYVQNM 1539 ++ D WAP Y+ KV+ +Y+Y ++K+DELSFQEG +IYV+KKN+DGW+EGVMNG TGLFPGNYV+++ Sbjct: 433 AEEDPPWAPRTYLEKVVAIYDYSKDKEDELSFQEGAIIYVIKKNDDGWYEGVMNGVTGLFPGNYVESI 500
BLAST of Abl interactor 2 vs. Ensembl Xenopus
Match: abi2 (abl-interactor 2 [Source:NCBI gene;Acc:548798]) HSP 1 Score: 118.242 bits (295), Expect = 1.448e-27 Identity = 64/151 (42.38%), Postives = 93/151 (61.59%), Query Frame = 1 Query: 58 ILLKEDIPNGTEDLINTSKTLEDVADHCLLTY------DRSLEQTVNYTAQALGSVAYKINLLATNFLEVLDKQNIKLNELQTKVNHLNMQVHIHQEKTARLSIGKYTMPRDPNVLKVSKVIEPLT-EIQGKYKRKEIDFSVLDNVGHGLK 489 +LL+E+IP G L+++ LE VAD+C Y R+LE+T YT Q+L SVAY IN LA N L++LD Q +L +++ +NH++ V IH+EK AR IG T + N + K+I P E +Y RK ID+++LD+ GHG+K Sbjct: 6 MLLEEEIPGGRRALLDSYTNLERVADYCENNYIQSPDKQRALEETKAYTTQSLASVAYLINTLANNVLQMLDIQASQLRRMESSINHISQTVDIHKEKVARREIGILTT--NKNTSRTHKIIAPANLERPVRYIRKPIDYTILDDTGHGVK 154 HSP 2 Score: 107.842 bits (268), Expect = 3.870e-24 Identity = 42/68 (61.76%), Postives = 58/68 (85.29%), Query Frame = 1 Query: 1336 SQVDDGWAPNQYICKVITLYEYQQNKDDELSFQEGELIYVVKKNNDGWWEGVMNGRTGLFPGNYVQNM 1539 ++ D WAP Y+ KV+ +Y+Y ++K+DELSFQEG +IYV+KKN+DGW+EGVMNG TGLFPGNYV+++ Sbjct: 466 AEEDPPWAPRTYLEKVVAIYDYSKDKEDELSFQEGAIIYVIKKNDDGWYEGVMNGVTGLFPGNYVESI 533
BLAST of Abl interactor 2 vs. Ensembl Xenopus
Match: abi2 (abl-interactor 2 [Source:NCBI gene;Acc:548798]) HSP 1 Score: 118.242 bits (295), Expect = 1.766e-27 Identity = 64/151 (42.38%), Postives = 93/151 (61.59%), Query Frame = 1 Query: 58 ILLKEDIPNGTEDLINTSKTLEDVADHCLLTY------DRSLEQTVNYTAQALGSVAYKINLLATNFLEVLDKQNIKLNELQTKVNHLNMQVHIHQEKTARLSIGKYTMPRDPNVLKVSKVIEPLT-EIQGKYKRKEIDFSVLDNVGHGLK 489 +LL+E+IP G L+++ LE VAD+C Y R+LE+T YT Q+L SVAY IN LA N L++LD Q +L +++ +NH++ V IH+EK AR IG T + N + K+I P E +Y RK ID+++LD+ GHG+K Sbjct: 6 MLLEEEIPGGRRALLDSYTNLERVADYCENNYIQSPDKQRALEETKAYTTQSLASVAYLINTLANNVLQMLDIQASQLRRMESSINHISQTVDIHKEKVARREIGILTT--NKNTSRTHKIIAPANLERPVRYIRKPIDYTILDDTGHGVK 154 HSP 2 Score: 107.457 bits (267), Expect = 5.486e-24 Identity = 42/68 (61.76%), Postives = 58/68 (85.29%), Query Frame = 1 Query: 1336 SQVDDGWAPNQYICKVITLYEYQQNKDDELSFQEGELIYVVKKNNDGWWEGVMNGRTGLFPGNYVQNM 1539 ++ D WAP Y+ KV+ +Y+Y ++K+DELSFQEG +IYV+KKN+DGW+EGVMNG TGLFPGNYV+++ Sbjct: 472 AEEDPPWAPRTYLEKVVAIYDYSKDKEDELSFQEGAIIYVIKKNDDGWYEGVMNGVTGLFPGNYVESI 539
BLAST of Abl interactor 2 vs. Ensembl Xenopus
Match: abi1 (abl interactor 1 [Source:NCBI gene;Acc:493216]) HSP 1 Score: 115.546 bits (288), Expect = 2.653e-27 Identity = 65/151 (43.05%), Postives = 94/151 (62.25%), Query Frame = 1 Query: 58 ILLKEDIPNGTEDLINTSKTLEDVADHCLLTY------DRSLEQTVNYTAQALGSVAYKINLLATNFLEVLDKQNIKLNELQTKVNHLNMQVHIHQEKTARLSIGKYTMPRDPNVLKVSKVIEPL-TEIQGKYKRKEIDFSVLDNVGHGLK 489 +LL+E+IP G + LI + L VAD+C Y ++LE+T YT Q+L SVAY+IN LA N L++LD Q +L +++ +NH++ V IH+EK AR IG T + N + K+I P E +Y RK ID++VLD+VGHG+K Sbjct: 6 MLLEEEIPAGKKALIESFHNLTRVADYCESNYIQAPDKRKALEETKAYTTQSLASVAYQINALANNVLQLLDIQASQLRRMESSINHISQTVDIHKEKVARREIGILTT--NKNTARSHKIIAPANMERPVRYIRKPIDYTVLDDVGHGVK 154 HSP 2 Score: 99.7525 bits (247), Expect = 5.755e-22 Identity = 43/80 (53.75%), Postives = 57/80 (71.25%), Query Frame = 1 Query: 1345 DDGWAPNQYICKVITLYEYQQNKDDELSFQEGELIYVVKKNNDGWWEGVMNGRTGLFPGNYVQNMN*SHN*FIIIFYYAD 1584 D WAP Y+ KV+ +Y+Y ++K+DELSF EG +IYV+KKN+DGW+EGV NG TGLFPGNYV+ + +YAD Sbjct: 324 DPIWAPKSYLEKVVAIYDYSKDKEDELSFMEGAIIYVIKKNDDGWYEGVSNGVTGLFPGNYVET----------VMHYAD 393
BLAST of Abl interactor 2 vs. Ensembl Xenopus
Match: abi2 (abl-interactor 2 [Source:NCBI gene;Acc:548798]) HSP 1 Score: 117.087 bits (292), Expect = 2.782e-27 Identity = 64/151 (42.38%), Postives = 93/151 (61.59%), Query Frame = 1 Query: 58 ILLKEDIPNGTEDLINTSKTLEDVADHCLLTY------DRSLEQTVNYTAQALGSVAYKINLLATNFLEVLDKQNIKLNELQTKVNHLNMQVHIHQEKTARLSIGKYTMPRDPNVLKVSKVIEPLT-EIQGKYKRKEIDFSVLDNVGHGLK 489 +LL+E+IP G L+++ LE VAD+C Y R+LE+T YT Q+L SVAY IN LA N L++LD Q +L +++ +NH++ V IH+EK AR IG T + N + K+I P E +Y RK ID+++LD+ GHG+K Sbjct: 6 MLLEEEIPGGRRALLDSYTNLERVADYCENNYIQSPDKQRALEETKAYTTQSLASVAYLINTLANNVLQMLDIQASQLRRMESSINHISQTVDIHKEKVARREIGILTT--NKNTSRTHKIIAPANLERPVRYIRKPIDYTILDDTGHGVK 154 HSP 2 Score: 105.916 bits (263), Expect = 1.248e-23 Identity = 42/68 (61.76%), Postives = 58/68 (85.29%), Query Frame = 1 Query: 1336 SQVDDGWAPNQYICKVITLYEYQQNKDDELSFQEGELIYVVKKNNDGWWEGVMNGRTGLFPGNYVQNM 1539 ++ D WAP Y+ KV+ +Y+Y ++K+DELSFQEG +IYV+KKN+DGW+EGVMNG TGLFPGNYV+++ Sbjct: 410 AEEDPPWAPRTYLEKVVAIYDYSKDKEDELSFQEGAIIYVIKKNDDGWYEGVMNGVTGLFPGNYVESI 477
BLAST of Abl interactor 2 vs. Ensembl Mouse
Match: Abi2 (abl-interactor 2 [Source:MGI Symbol;Acc:MGI:106913]) HSP 1 Score: 118.627 bits (296), Expect = 6.499e-28 Identity = 64/151 (42.38%), Postives = 93/151 (61.59%), Query Frame = 1 Query: 58 ILLKEDIPNGTEDLINTSKTLEDVADHCLLTY------DRSLEQTVNYTAQALGSVAYKINLLATNFLEVLDKQNIKLNELQTKVNHLNMQVHIHQEKTARLSIGKYTMPRDPNVLKVSKVIEPLT-EIQGKYKRKEIDFSVLDNVGHGLK 489 +LL+E+IP G L ++ LE VAD+C Y R+LE+T YT Q+L SVAY IN LA N L++LD Q +L +++ +NH++ V IH+EK AR IG T + N + K+I P E +Y RK ID+++LD++GHG+K Sbjct: 6 MLLEEEIPGGRRALFDSYTNLERVADYCENNYIQSPDKQRALEETKAYTTQSLASVAYLINTLANNVLQMLDIQASQLRRMESSINHISQTVDIHKEKVARREIGILTT--NKNTSRTHKIIAPANLERPVRYIRKPIDYTILDDIGHGVK 154 HSP 2 Score: 65.4698 bits (158), Expect = 9.111e-11 Identity = 25/46 (54.35%), Postives = 37/46 (80.43%), Query Frame = 1 Query: 1336 SQVDDGWAPNQYICKVITLYEYQQNKDDELSFQEGELIYVVKKNND 1473 ++ D WAP Y+ KV+ +Y+Y ++K+DELSFQEG +IYV+KKN+D Sbjct: 441 AEEDPPWAPRAYLEKVVAIYDYTKDKEDELSFQEGAIIYVIKKNDD 486
BLAST of Abl interactor 2 vs. Ensembl Mouse
Match: Abi2 (abl-interactor 2 [Source:MGI Symbol;Acc:MGI:106913]) HSP 1 Score: 117.857 bits (294), Expect = 8.121e-28 Identity = 64/151 (42.38%), Postives = 93/151 (61.59%), Query Frame = 1 Query: 58 ILLKEDIPNGTEDLINTSKTLEDVADHCLLTY------DRSLEQTVNYTAQALGSVAYKINLLATNFLEVLDKQNIKLNELQTKVNHLNMQVHIHQEKTARLSIGKYTMPRDPNVLKVSKVIEPLT-EIQGKYKRKEIDFSVLDNVGHGLK 489 +LL+E+IP G L ++ LE VAD+C Y R+LE+T YT Q+L SVAY IN LA N L++LD Q +L +++ +NH++ V IH+EK AR IG T + N + K+I P E +Y RK ID+++LD++GHG+K Sbjct: 6 MLLEEEIPGGRRALFDSYTNLERVADYCENNYIQSPDKQRALEETKAYTTQSLASVAYLINTLANNVLQMLDIQASQLRRMESSINHISQTVDIHKEKVARREIGILTT--NKNTSRTHKIIAPANLERPVRYIRKPIDYTILDDIGHGVK 154 HSP 2 Score: 105.916 bits (263), Expect = 7.611e-24 Identity = 42/68 (61.76%), Postives = 58/68 (85.29%), Query Frame = 1 Query: 1336 SQVDDGWAPNQYICKVITLYEYQQNKDDELSFQEGELIYVVKKNNDGWWEGVMNGRTGLFPGNYVQNM 1539 ++ D WAP Y+ KV+ +Y+Y ++K+DELSFQEG +IYV+KKN+DGW+EGVMNG TGLFPGNYV+++ Sbjct: 374 AEEDPPWAPRAYLEKVVAIYDYTKDKEDELSFQEGAIIYVIKKNDDGWYEGVMNGVTGLFPGNYVESI 441
BLAST of Abl interactor 2 vs. Ensembl Mouse
Match: Abi2 (abl-interactor 2 [Source:MGI Symbol;Acc:MGI:106913]) HSP 1 Score: 117.857 bits (294), Expect = 8.483e-28 Identity = 64/151 (42.38%), Postives = 93/151 (61.59%), Query Frame = 1 Query: 58 ILLKEDIPNGTEDLINTSKTLEDVADHCLLTY------DRSLEQTVNYTAQALGSVAYKINLLATNFLEVLDKQNIKLNELQTKVNHLNMQVHIHQEKTARLSIGKYTMPRDPNVLKVSKVIEPLT-EIQGKYKRKEIDFSVLDNVGHGLK 489 +LL+E+IP G L ++ LE VAD+C Y R+LE+T YT Q+L SVAY IN LA N L++LD Q +L +++ +NH++ V IH+EK AR IG T + N + K+I P E +Y RK ID+++LD++GHG+K Sbjct: 6 MLLEEEIPGGRRALFDSYTNLERVADYCENNYIQSPDKQRALEETKAYTTQSLASVAYLINTLANNVLQMLDIQASQLRRMESSINHISQTVDIHKEKVARREIGILTT--NKNTSRTHKIIAPANLERPVRYIRKPIDYTILDDIGHGVK 154 HSP 2 Score: 106.686 bits (265), Expect = 3.968e-24 Identity = 42/68 (61.76%), Postives = 58/68 (85.29%), Query Frame = 1 Query: 1336 SQVDDGWAPNQYICKVITLYEYQQNKDDELSFQEGELIYVVKKNNDGWWEGVMNGRTGLFPGNYVQNM 1539 ++ D WAP Y+ KV+ +Y+Y ++K+DELSFQEG +IYV+KKN+DGW+EGVMNG TGLFPGNYV+++ Sbjct: 386 AEEDPPWAPRAYLEKVVAIYDYTKDKEDELSFQEGAIIYVIKKNDDGWYEGVMNGVTGLFPGNYVESI 453
BLAST of Abl interactor 2 vs. Ensembl Mouse
Match: Abi2 (abl-interactor 2 [Source:MGI Symbol;Acc:MGI:106913]) HSP 1 Score: 117.857 bits (294), Expect = 9.925e-28 Identity = 64/151 (42.38%), Postives = 93/151 (61.59%), Query Frame = 1 Query: 58 ILLKEDIPNGTEDLINTSKTLEDVADHCLLTY------DRSLEQTVNYTAQALGSVAYKINLLATNFLEVLDKQNIKLNELQTKVNHLNMQVHIHQEKTARLSIGKYTMPRDPNVLKVSKVIEPLT-EIQGKYKRKEIDFSVLDNVGHGLK 489 +LL+E+IP G L ++ LE VAD+C Y R+LE+T YT Q+L SVAY IN LA N L++LD Q +L +++ +NH++ V IH+EK AR IG T + N + K+I P E +Y RK ID+++LD++GHG+K Sbjct: 6 MLLEEEIPGGRRALFDSYTNLERVADYCENNYIQSPDKQRALEETKAYTTQSLASVAYLINTLANNVLQMLDIQASQLRRMESSINHISQTVDIHKEKVARREIGILTT--NKNTSRTHKIIAPANLERPVRYIRKPIDYTILDDIGHGVK 154 HSP 2 Score: 105.916 bits (263), Expect = 1.020e-23 Identity = 42/68 (61.76%), Postives = 58/68 (85.29%), Query Frame = 1 Query: 1336 SQVDDGWAPNQYICKVITLYEYQQNKDDELSFQEGELIYVVKKNNDGWWEGVMNGRTGLFPGNYVQNM 1539 ++ D WAP Y+ KV+ +Y+Y ++K+DELSFQEG +IYV+KKN+DGW+EGVMNG TGLFPGNYV+++ Sbjct: 408 AEEDPPWAPRAYLEKVVAIYDYTKDKEDELSFQEGAIIYVIKKNDDGWYEGVMNGVTGLFPGNYVESI 475
BLAST of Abl interactor 2 vs. Ensembl Mouse
Match: Abi1 (abl-interactor 1 [Source:MGI Symbol;Acc:MGI:104913]) HSP 1 Score: 116.316 bits (290), Expect = 1.019e-27 Identity = 65/151 (43.05%), Postives = 95/151 (62.91%), Query Frame = 1 Query: 58 ILLKEDIPNGTEDLINTSKTLEDVADHCLLTY------DRSLEQTVNYTAQALGSVAYKINLLATNFLEVLDKQNIKLNELQTKVNHLNMQVHIHQEKTARLSIGKYTMPRDPNVLKVSKVIEPL-TEIQGKYKRKEIDFSVLDNVGHGLK 489 +LL+E+IP+G LI + + L VAD+C Y ++LE+T YT Q+L SVAY+IN LA N L++LD Q +L +++ +NH++ V IH+EK AR IG T + N + K+I P E +Y RK ID++VLD+VGHG+K Sbjct: 6 MLLEEEIPSGKRALIESYQNLTRVADYCENNYIQATDKRKALEETKAYTTQSLASVAYQINALANNVLQLLDIQASQLRRMESSINHISQTVDIHKEKVARREIGILTT--NKNTSRTHKIIAPANMERPVRYIRKPIDYTVLDDVGHGVK 154 HSP 2 Score: 102.064 bits (253), Expect = 6.328e-23 Identity = 41/65 (63.08%), Postives = 54/65 (83.08%), Query Frame = 1 Query: 1345 DDGWAPNQYICKVITLYEYQQNKDDELSFQEGELIYVVKKNNDGWWEGVMNGRTGLFPGNYVQNM 1539 D WAP YI KV+ +Y+Y ++KDDELSF+EG +IYV+KKN+DGW+EGV N TGLFPGNYV+++ Sbjct: 319 DPAWAPKNYIEKVVAIYDYTKDKDDELSFKEGAIIYVIKKNDDGWFEGVCNRVTGLFPGNYVESI 383
BLAST of Abl interactor 2 vs. UniProt/SwissProt
Match: sp|P62484|ABI2_MOUSE (Abl interactor 2 OS=Mus musculus OX=10090 GN=Abi2 PE=1 SV=1) HSP 1 Score: 117.857 bits (294), Expect = 5.681e-27 Identity = 64/151 (42.38%), Postives = 93/151 (61.59%), Query Frame = 1 Query: 58 ILLKEDIPNGTEDLINTSKTLEDVADHCLLTY------DRSLEQTVNYTAQALGSVAYKINLLATNFLEVLDKQNIKLNELQTKVNHLNMQVHIHQEKTARLSIGKYTMPRDPNVLKVSKVIEPLT-EIQGKYKRKEIDFSVLDNVGHGLK 489 +LL+E+IP G L ++ LE VAD+C Y R+LE+T YT Q+L SVAY IN LA N L++LD Q +L +++ +NH++ V IH+EK AR IG T + N + K+I P E +Y RK ID+++LD++GHG+K Sbjct: 6 MLLEEEIPGGRRALFDSYTNLERVADYCENNYIQSPDKQRALEETKAYTTQSLASVAYLINTLANNVLQMLDIQASQLRRMESSINHISQTVDIHKEKVARREIGILTT--NKNTSRTHKIIAPANLERPVRYIRKPIDYTILDDIGHGVK 154 HSP 2 Score: 105.916 bits (263), Expect = 5.324e-23 Identity = 42/68 (61.76%), Postives = 58/68 (85.29%), Query Frame = 1 Query: 1336 SQVDDGWAPNQYICKVITLYEYQQNKDDELSFQEGELIYVVKKNNDGWWEGVMNGRTGLFPGNYVQNM 1539 ++ D WAP Y+ KV+ +Y+Y ++K+DELSFQEG +IYV+KKN+DGW+EGVMNG TGLFPGNYV+++ Sbjct: 374 AEEDPPWAPRAYLEKVVAIYDYTKDKEDELSFQEGAIIYVIKKNDDGWYEGVMNGVTGLFPGNYVESI 441
BLAST of Abl interactor 2 vs. UniProt/SwissProt
Match: sp|Q9NYB9|ABI2_HUMAN (Abl interactor 2 OS=Homo sapiens OX=9606 GN=ABI2 PE=1 SV=1) HSP 1 Score: 118.242 bits (295), Expect = 6.426e-27 Identity = 64/151 (42.38%), Postives = 93/151 (61.59%), Query Frame = 1 Query: 58 ILLKEDIPNGTEDLINTSKTLEDVADHCLLTY------DRSLEQTVNYTAQALGSVAYKINLLATNFLEVLDKQNIKLNELQTKVNHLNMQVHIHQEKTARLSIGKYTMPRDPNVLKVSKVIEPLT-EIQGKYKRKEIDFSVLDNVGHGLK 489 +LL+E+IP G L ++ LE VAD+C Y R+LE+T YT Q+L SVAY IN LA N L++LD Q +L +++ +NH++ V IH+EK AR IG T + N + K+I P E +Y RK ID+++LD++GHG+K Sbjct: 6 MLLEEEIPGGRRALFDSYTNLERVADYCENNYIQSADKQRALEETKAYTTQSLASVAYLINTLANNVLQMLDIQASQLRRMESSINHISQTVDIHKEKVARREIGILTT--NKNTSRTHKIIAPANLERPVRYIRKPIDYTILDDIGHGVK 154 HSP 2 Score: 107.071 bits (266), Expect = 3.230e-23 Identity = 42/68 (61.76%), Postives = 58/68 (85.29%), Query Frame = 1 Query: 1336 SQVDDGWAPNQYICKVITLYEYQQNKDDELSFQEGELIYVVKKNNDGWWEGVMNGRTGLFPGNYVQNM 1539 ++ D WAP Y+ KV+ +Y+Y ++K+DELSFQEG +IYV+KKN+DGW+EGVMNG TGLFPGNYV+++ Sbjct: 441 AEEDPPWAPRSYLEKVVAIYDYTKDKEDELSFQEGAIIYVIKKNDDGWYEGVMNGVTGLFPGNYVESI 508
BLAST of Abl interactor 2 vs. UniProt/SwissProt
Match: sp|Q9QZM5|ABI1_RAT (Abl interactor 1 OS=Rattus norvegicus OX=10116 GN=Abi1 PE=1 SV=3) HSP 1 Score: 117.087 bits (292), Expect = 1.302e-26 Identity = 65/151 (43.05%), Postives = 95/151 (62.91%), Query Frame = 1 Query: 58 ILLKEDIPNGTEDLINTSKTLEDVADHCLLTY------DRSLEQTVNYTAQALGSVAYKINLLATNFLEVLDKQNIKLNELQTKVNHLNMQVHIHQEKTARLSIGKYTMPRDPNVLKVSKVIEPL-TEIQGKYKRKEIDFSVLDNVGHGLK 489 +LL+E+IP+G LI + + L VAD+C Y ++LE+T YT Q+L SVAY+IN LA N L++LD Q +L +++ +NH++ V IH+EK AR IG T + N + K+I P E +Y RK ID++VLD+VGHG+K Sbjct: 6 MLLEEEIPSGKRALIESYQNLTRVADYCENNYIQATDKRKALEETKAYTTQSLASVAYQINALANNVLQLLDIQASQLRRMESSINHISQTVDIHKEKVARREIGILTT--NKNTSRTHKIIAPANMERPVRYIRKPIDYTVLDDVGHGVK 154 HSP 2 Score: 102.449 bits (254), Expect = 9.340e-22 Identity = 41/65 (63.08%), Postives = 54/65 (83.08%), Query Frame = 1 Query: 1345 DDGWAPNQYICKVITLYEYQQNKDDELSFQEGELIYVVKKNNDGWWEGVMNGRTGLFPGNYVQNM 1539 D WAP YI KV+ +Y+Y ++KDDELSF+EG +IYV+KKN+DGW+EGV N TGLFPGNYV+++ Sbjct: 407 DPAWAPKNYIEKVVAIYDYTKDKDDELSFKEGAIIYVIKKNDDGWFEGVCNRVTGLFPGNYVESI 471
BLAST of Abl interactor 2 vs. UniProt/SwissProt
Match: sp|Q8CBW3|ABI1_MOUSE (Abl interactor 1 OS=Mus musculus OX=10090 GN=Abi1 PE=1 SV=3) HSP 1 Score: 117.087 bits (292), Expect = 1.368e-26 Identity = 65/151 (43.05%), Postives = 95/151 (62.91%), Query Frame = 1 Query: 58 ILLKEDIPNGTEDLINTSKTLEDVADHCLLTY------DRSLEQTVNYTAQALGSVAYKINLLATNFLEVLDKQNIKLNELQTKVNHLNMQVHIHQEKTARLSIGKYTMPRDPNVLKVSKVIEPL-TEIQGKYKRKEIDFSVLDNVGHGLK 489 +LL+E+IP+G LI + + L VAD+C Y ++LE+T YT Q+L SVAY+IN LA N L++LD Q +L +++ +NH++ V IH+EK AR IG T + N + K+I P E +Y RK ID++VLD+VGHG+K Sbjct: 6 MLLEEEIPSGKRALIESYQNLTRVADYCENNYIQATDKRKALEETKAYTTQSLASVAYQINALANNVLQLLDIQASQLRRMESSINHISQTVDIHKEKVARREIGILTT--NKNTSRTHKIIAPANMERPVRYIRKPIDYTVLDDVGHGVK 154 HSP 2 Score: 102.064 bits (253), Expect = 1.260e-21 Identity = 41/65 (63.08%), Postives = 54/65 (83.08%), Query Frame = 1 Query: 1345 DDGWAPNQYICKVITLYEYQQNKDDELSFQEGELIYVVKKNNDGWWEGVMNGRTGLFPGNYVQNM 1539 D WAP YI KV+ +Y+Y ++KDDELSF+EG +IYV+KKN+DGW+EGV N TGLFPGNYV+++ Sbjct: 412 DPAWAPKNYIEKVVAIYDYTKDKDDELSFKEGAIIYVIKKNDDGWFEGVCNRVTGLFPGNYVESI 476
BLAST of Abl interactor 2 vs. UniProt/SwissProt
Match: sp|Q8IZP0|ABI1_HUMAN (Abl interactor 1 OS=Homo sapiens OX=9606 GN=ABI1 PE=1 SV=4) HSP 1 Score: 117.087 bits (292), Expect = 1.466e-26 Identity = 65/151 (43.05%), Postives = 95/151 (62.91%), Query Frame = 1 Query: 58 ILLKEDIPNGTEDLINTSKTLEDVADHCLLTY------DRSLEQTVNYTAQALGSVAYKINLLATNFLEVLDKQNIKLNELQTKVNHLNMQVHIHQEKTARLSIGKYTMPRDPNVLKVSKVIEPL-TEIQGKYKRKEIDFSVLDNVGHGLK 489 +LL+E+IP+G LI + + L VAD+C Y ++LE+T YT Q+L SVAY+IN LA N L++LD Q +L +++ +NH++ V IH+EK AR IG T + N + K+I P E +Y RK ID++VLD+VGHG+K Sbjct: 6 MLLEEEIPSGKRALIESYQNLTRVADYCENNYIQATDKRKALEETKAYTTQSLASVAYQINALANNVLQLLDIQASQLRRMESSINHISQTVDIHKEKVARREIGILTT--NKNTSRTHKIIAPANMERPVRYIRKPIDYTVLDDVGHGVK 154 HSP 2 Score: 101.679 bits (252), Expect = 2.211e-21 Identity = 41/65 (63.08%), Postives = 53/65 (81.54%), Query Frame = 1 Query: 1345 DDGWAPNQYICKVITLYEYQQNKDDELSFQEGELIYVVKKNNDGWWEGVMNGRTGLFPGNYVQNM 1539 D WAP YI KV+ +Y+Y ++KDDELSF EG +IYV+KKN+DGW+EGV N TGLFPGNYV+++ Sbjct: 439 DPAWAPKNYIEKVVAIYDYTKDKDDELSFMEGAIIYVIKKNDDGWYEGVCNRVTGLFPGNYVESI 503
BLAST of Abl interactor 2 vs. TrEMBL
Match: A0A3P7BEX1 (SH3 domain-containing protein OS=Schistocephalus solidus OX=70667 GN=SSLN_LOCUS202 PE=4 SV=1) HSP 1 Score: 126.716 bits (317), Expect = 3.216e-29 Identity = 57/84 (67.86%), Postives = 68/84 (80.95%), Query Frame = 1 Query: 1282 TVGIAHLQPNPYDVLRVKSQVDDGWAPNQYICKVITLYEYQQNKDDELSFQEGELIYVVKKNNDGWWEGVMNGRTGLFPGNYVQ 1533 TV I+ LQP+P D LR + D WAPNQYI KVIT+YEY +K+DEL+F E ELIYV+KKN+DGWWEGVM+G TGLFPGNYV+ Sbjct: 166 TVDISRLQPSPMDQLRPRRPDDAPWAPNQYIQKVITVYEYTADKNDELTFGENELIYVIKKNDDGWWEGVMSGSTGLFPGNYVE 249
BLAST of Abl interactor 2 vs. TrEMBL
Match: A0A183S7K4 (SH3 domain-containing protein OS=Schistocephalus solidus OX=70667 PE=4 SV=1) HSP 1 Score: 126.716 bits (317), Expect = 3.620e-29 Identity = 57/84 (67.86%), Postives = 68/84 (80.95%), Query Frame = 1 Query: 1282 TVGIAHLQPNPYDVLRVKSQVDDGWAPNQYICKVITLYEYQQNKDDELSFQEGELIYVVKKNNDGWWEGVMNGRTGLFPGNYVQ 1533 TV I+ LQP+P D LR + D WAPNQYI KVIT+YEY +K+DEL+F E ELIYV+KKN+DGWWEGVM+G TGLFPGNYV+ Sbjct: 166 TVDISRLQPSPMDQLRPRRPDDAPWAPNQYIQKVITVYEYTADKNDELTFGENELIYVIKKNDDGWWEGVMSGSTGLFPGNYVE 249
BLAST of Abl interactor 2 vs. TrEMBL
Match: A0A0V0JB58 (Zinc finger protein 330 OS=Schistocephalus solidus OX=70667 GN=ZN330 PE=4 SV=1) HSP 1 Score: 127.872 bits (320), Expect = 3.025e-28 Identity = 57/85 (67.06%), Postives = 68/85 (80.00%), Query Frame = 1 Query: 1279 DTVGIAHLQPNPYDVLRVKSQVDDGWAPNQYICKVITLYEYQQNKDDELSFQEGELIYVVKKNNDGWWEGVMNGRTGLFPGNYVQ 1533 TV I+ LQP+P D LR + D WAPNQYI KVIT+YEY +K+DEL+F E ELIYV+KKN+DGWWEGVM+G TGLFPGNYV+ Sbjct: 324 STVDISRLQPSPMDQLRPRRPDDAPWAPNQYIQKVITVYEYTADKNDELTFGENELIYVIKKNDDGWWEGVMSGSTGLFPGNYVE 408
BLAST of Abl interactor 2 vs. TrEMBL
Match: A0A0V0J3G4 (Zinc finger protein 330 (Fragment) OS=Schistocephalus solidus OX=70667 GN=ZN330 PE=4 SV=1) HSP 1 Score: 129.413 bits (324), Expect = 6.659e-28 Identity = 57/85 (67.06%), Postives = 68/85 (80.00%), Query Frame = 1 Query: 1279 DTVGIAHLQPNPYDVLRVKSQVDDGWAPNQYICKVITLYEYQQNKDDELSFQEGELIYVVKKNNDGWWEGVMNGRTGLFPGNYVQ 1533 TV I+ LQP+P D LR + D WAPNQYI KVIT+YEY +K+DEL+F E ELIYV+KKN+DGWWEGVM+G TGLFPGNYV+ Sbjct: 512 STVDISRLQPSPMDQLRPRRPDDAPWAPNQYIQKVITVYEYTADKNDELTFGENELIYVIKKNDDGWWEGVMSGSTGLFPGNYVE 596 HSP 2 Score: 95.5153 bits (236), Expect = 7.566e-17 Identity = 52/151 (34.44%), Postives = 88/151 (58.28%), Query Frame = 1 Query: 55 IILLKEDIPNGTEDLINTSKTLEDVADHCLLTYDRS------LEQTVNYTAQALGSVAYKINLLATNFLEVLDKQNIKLNELQTKVNHLNMQVHIHQEKTARLSIGKYTMPRDPNVLKVSKVIEPLTEIQGKYKRKEIDFSVLDNVGHGLK 489 + ++ + + NG L+ T+ +E A +C Y S + +T+NY Q+LG++ ++++ LAT FL VLD++ L ++ KV+ L M++ I QEK AR +IG T+ + P SK+ + E + R+ IDF+VLD++GHG K Sbjct: 23 MFIMSDVVNNGKNALLQTAANIEQAAAYCSSNYLNSHNQKDAIGETMNYATQSLGTMIHQLSQLATTFLRVLDEKVDNLANIEDKVSKLGMELKIRQEKIARKAIGSCTVSKVPVKYAHSKLRQ---EPPADFIRRPIDFTVLDHIGHGFK 170
BLAST of Abl interactor 2 vs. TrEMBL
Match: A0A0V0J558 (Zinc finger protein 330 (Fragment) OS=Schistocephalus solidus OX=70667 GN=ZN330 PE=4 SV=1) HSP 1 Score: 129.413 bits (324), Expect = 7.007e-28 Identity = 57/85 (67.06%), Postives = 68/85 (80.00%), Query Frame = 1 Query: 1279 DTVGIAHLQPNPYDVLRVKSQVDDGWAPNQYICKVITLYEYQQNKDDELSFQEGELIYVVKKNNDGWWEGVMNGRTGLFPGNYVQ 1533 TV I+ LQP+P D LR + D WAPNQYI KVIT+YEY +K+DEL+F E ELIYV+KKN+DGWWEGVM+G TGLFPGNYV+ Sbjct: 520 STVDISRLQPSPMDQLRPRRPDDAPWAPNQYIQKVITVYEYTADKNDELTFGENELIYVIKKNDDGWWEGVMSGSTGLFPGNYVE 604 HSP 2 Score: 95.5153 bits (236), Expect = 7.594e-17 Identity = 52/151 (34.44%), Postives = 88/151 (58.28%), Query Frame = 1 Query: 55 IILLKEDIPNGTEDLINTSKTLEDVADHCLLTYDRS------LEQTVNYTAQALGSVAYKINLLATNFLEVLDKQNIKLNELQTKVNHLNMQVHIHQEKTARLSIGKYTMPRDPNVLKVSKVIEPLTEIQGKYKRKEIDFSVLDNVGHGLK 489 + ++ + + NG L+ T+ +E A +C Y S + +T+NY Q+LG++ ++++ LAT FL VLD++ L ++ KV+ L M++ I QEK AR +IG T+ + P SK+ + E + R+ IDF+VLD++GHG K Sbjct: 23 MFIMSDVVNNGKNALLQTAANIEQAAAYCSSNYLNSHNQKDAIGETMNYATQSLGTMIHQLSQLATTFLRVLDEKVDNLANIEDKVSKLGMELKIRQEKIARKAIGSCTVSKVPVKYAHSKLRQ---EPPADFIRRPIDFTVLDHIGHGFK 170
BLAST of Abl interactor 2 vs. Ensembl Cavefish
Match: abi2b (abl interactor 2 [Source:NCBI gene;Acc:103021515]) HSP 1 Score: 118.242 bits (295), Expect = 7.338e-28 Identity = 65/151 (43.05%), Postives = 95/151 (62.91%), Query Frame = 1 Query: 58 ILLKEDIPNGTEDLINTSKTLEDVADHCLLTY------DRSLEQTVNYTAQALGSVAYKINLLATNFLEVLDKQNIKLNELQTKVNHLNMQVHIHQEKTARLSIGKYTMPRDPNVLKVSKVIEPLT-EIQGKYKRKEIDFSVLDNVGHGLK 489 +LL+E+IP G L+++ LE VA++C Y R+LE+T +YT Q+L SVAY IN LA N L++LD Q +L +++ +NH++ V IH+EK AR IG T + N + K+I P E +Y RK ID+S+LD+VGHG+K Sbjct: 6 MLLEEEIPAGRGALLDSYANLERVAEYCESNYIQSPDKQRALEETKSYTTQSLASVAYLINTLANNVLQMLDIQASQLRRMESSINHISQTVDIHKEKVARREIGILTT--NKNTSRTHKIIAPANPERPVRYIRKPIDYSLLDDVGHGVK 154 HSP 2 Score: 107.842 bits (268), Expect = 1.769e-24 Identity = 46/83 (55.42%), Postives = 62/83 (74.70%), Query Frame = 1 Query: 1336 SQVDDGWAPNQYICKVITLYEYQQNKDDELSFQEGELIYVVKKNNDGWWEGVMNGRTGLFPGNYVQNMN*SHN*FIIIFYYAD 1584 ++ D WAP Y+ KV+ +Y+Y ++K+DELSFQEG +IYV+KKN+DGW+EGVMNG TGLFPGNYV++ I +YAD Sbjct: 424 AEEDPPWAPRSYMEKVVAIYDYARDKEDELSFQEGAIIYVIKKNDDGWYEGVMNGTTGLFPGNYVES----------IMHYAD 496
BLAST of Abl interactor 2 vs. Ensembl Cavefish
Match: abi2b (abl interactor 2 [Source:NCBI gene;Acc:103021515]) HSP 1 Score: 118.627 bits (296), Expect = 9.621e-28 Identity = 65/151 (43.05%), Postives = 95/151 (62.91%), Query Frame = 1 Query: 58 ILLKEDIPNGTEDLINTSKTLEDVADHCLLTY------DRSLEQTVNYTAQALGSVAYKINLLATNFLEVLDKQNIKLNELQTKVNHLNMQVHIHQEKTARLSIGKYTMPRDPNVLKVSKVIEPLT-EIQGKYKRKEIDFSVLDNVGHGLK 489 +LL+E+IP G L+++ LE VA++C Y R+LE+T +YT Q+L SVAY IN LA N L++LD Q +L +++ +NH++ V IH+EK AR IG T + N + K+I P E +Y RK ID+S+LD+VGHG+K Sbjct: 6 MLLEEEIPAGRGALLDSYANLERVAEYCESNYIQSPDKQRALEETKSYTTQSLASVAYLINTLANNVLQMLDIQASQLRRMESSINHISQTVDIHKEKVARREIGILTT--NKNTSRTHKIIAPANPERPVRYIRKPIDYSLLDDVGHGVK 154 HSP 2 Score: 108.612 bits (270), Expect = 1.831e-24 Identity = 46/83 (55.42%), Postives = 62/83 (74.70%), Query Frame = 1 Query: 1336 SQVDDGWAPNQYICKVITLYEYQQNKDDELSFQEGELIYVVKKNNDGWWEGVMNGRTGLFPGNYVQNMN*SHN*FIIIFYYAD 1584 ++ D WAP Y+ KV+ +Y+Y ++K+DELSFQEG +IYV+KKN+DGW+EGVMNG TGLFPGNYV++ I +YAD Sbjct: 495 AEEDPPWAPRSYMEKVVAIYDYARDKEDELSFQEGAIIYVIKKNDDGWYEGVMNGTTGLFPGNYVES----------IMHYAD 567
BLAST of Abl interactor 2 vs. Ensembl Cavefish
Match: abi2b (abl interactor 2 [Source:NCBI gene;Acc:103021515]) HSP 1 Score: 118.627 bits (296), Expect = 1.053e-27 Identity = 65/151 (43.05%), Postives = 95/151 (62.91%), Query Frame = 1 Query: 58 ILLKEDIPNGTEDLINTSKTLEDVADHCLLTY------DRSLEQTVNYTAQALGSVAYKINLLATNFLEVLDKQNIKLNELQTKVNHLNMQVHIHQEKTARLSIGKYTMPRDPNVLKVSKVIEPLT-EIQGKYKRKEIDFSVLDNVGHGLK 489 +LL+E+IP G L+++ LE VA++C Y R+LE+T +YT Q+L SVAY IN LA N L++LD Q +L +++ +NH++ V IH+EK AR IG T + N + K+I P E +Y RK ID+S+LD+VGHG+K Sbjct: 6 MLLEEEIPAGRGALLDSYANLERVAEYCESNYIQSPDKQRALEETKSYTTQSLASVAYLINTLANNVLQMLDIQASQLRRMESSINHISQTVDIHKEKVARREIGILTT--NKNTSRTHKIIAPANPERPVRYIRKPIDYSLLDDVGHGVK 154 HSP 2 Score: 108.227 bits (269), Expect = 2.532e-24 Identity = 46/83 (55.42%), Postives = 62/83 (74.70%), Query Frame = 1 Query: 1336 SQVDDGWAPNQYICKVITLYEYQQNKDDELSFQEGELIYVVKKNNDGWWEGVMNGRTGLFPGNYVQNMN*SHN*FIIIFYYAD 1584 ++ D WAP Y+ KV+ +Y+Y ++K+DELSFQEG +IYV+KKN+DGW+EGVMNG TGLFPGNYV++ I +YAD Sbjct: 501 AEEDPPWAPRSYMEKVVAIYDYARDKEDELSFQEGAIIYVIKKNDDGWYEGVMNGTTGLFPGNYVES----------IMHYAD 573
BLAST of Abl interactor 2 vs. Ensembl Cavefish
Match: abi2b (abl interactor 2 [Source:NCBI gene;Acc:103021515]) HSP 1 Score: 118.242 bits (295), Expect = 1.140e-27 Identity = 65/151 (43.05%), Postives = 95/151 (62.91%), Query Frame = 1 Query: 58 ILLKEDIPNGTEDLINTSKTLEDVADHCLLTY------DRSLEQTVNYTAQALGSVAYKINLLATNFLEVLDKQNIKLNELQTKVNHLNMQVHIHQEKTARLSIGKYTMPRDPNVLKVSKVIEPLT-EIQGKYKRKEIDFSVLDNVGHGLK 489 +LL+E+IP G L+++ LE VA++C Y R+LE+T +YT Q+L SVAY IN LA N L++LD Q +L +++ +NH++ V IH+EK AR IG T + N + K+I P E +Y RK ID+S+LD+VGHG+K Sbjct: 6 MLLEEEIPAGRGALLDSYANLERVAEYCESNYIQSPDKQRALEETKSYTTQSLASVAYLINTLANNVLQMLDIQASQLRRMESSINHISQTVDIHKEKVARREIGILTT--NKNTSRTHKIIAPANPERPVRYIRKPIDYSLLDDVGHGVK 154 HSP 2 Score: 107.457 bits (267), Expect = 3.413e-24 Identity = 46/83 (55.42%), Postives = 62/83 (74.70%), Query Frame = 1 Query: 1336 SQVDDGWAPNQYICKVITLYEYQQNKDDELSFQEGELIYVVKKNNDGWWEGVMNGRTGLFPGNYVQNMN*SHN*FIIIFYYAD 1584 ++ D WAP Y+ KV+ +Y+Y ++K+DELSFQEG +IYV+KKN+DGW+EGVMNG TGLFPGNYV++ I +YAD Sbjct: 472 AEEDPPWAPRSYMEKVVAIYDYARDKEDELSFQEGAIIYVIKKNDDGWYEGVMNGTTGLFPGNYVES----------IMHYAD 544
BLAST of Abl interactor 2 vs. Ensembl Cavefish
Match: abi2b (abl interactor 2 [Source:NCBI gene;Acc:103021515]) HSP 1 Score: 117.472 bits (293), Expect = 1.448e-27 Identity = 65/151 (43.05%), Postives = 95/151 (62.91%), Query Frame = 1 Query: 58 ILLKEDIPNGTEDLINTSKTLEDVADHCLLTY------DRSLEQTVNYTAQALGSVAYKINLLATNFLEVLDKQNIKLNELQTKVNHLNMQVHIHQEKTARLSIGKYTMPRDPNVLKVSKVIEPLT-EIQGKYKRKEIDFSVLDNVGHGLK 489 +LL+E+IP G L+++ LE VA++C Y R+LE+T +YT Q+L SVAY IN LA N L++LD Q +L +++ +NH++ V IH+EK AR IG T + N + K+I P E +Y RK ID+S+LD+VGHG+K Sbjct: 6 MLLEEEIPAGRGALLDSYANLERVAEYCESNYIQSPDKQRALEETKSYTTQSLASVAYLINTLANNVLQMLDIQASQLRRMESSINHISQTVDIHKEKVARREIGILTT--NKNTSRTHKIIAPANPERPVRYIRKPIDYSLLDDVGHGVK 154 HSP 2 Score: 107.071 bits (266), Expect = 3.782e-24 Identity = 46/83 (55.42%), Postives = 62/83 (74.70%), Query Frame = 1 Query: 1336 SQVDDGWAPNQYICKVITLYEYQQNKDDELSFQEGELIYVVKKNNDGWWEGVMNGRTGLFPGNYVQNMN*SHN*FIIIFYYAD 1584 ++ D WAP Y+ KV+ +Y+Y ++K+DELSFQEG +IYV+KKN+DGW+EGVMNG TGLFPGNYV++ I +YAD Sbjct: 452 AEEDPPWAPRSYMEKVVAIYDYARDKEDELSFQEGAIIYVIKKNDDGWYEGVMNGTTGLFPGNYVES----------IMHYAD 524
BLAST of Abl interactor 2 vs. Ensembl Sea Lamprey
Match: ABI1 (abl interactor 1 [Source:HGNC Symbol;Acc:HGNC:11320]) HSP 1 Score: 104.375 bits (259), Expect = 3.780e-24 Identity = 41/66 (62.12%), Postives = 56/66 (84.85%), Query Frame = 1 Query: 1336 SQVDDGWAPNQYICKVITLYEYQQNKDDELSFQEGELIYVVKKNNDGWWEGVMNGRTGLFPGNYVQ 1533 ++ D WAP Y+ KV+ +Y+Y ++K+DELSFQEG +IYV+KKN+DGW+EG MNG+TGLFPGNYV+ Sbjct: 382 AEADPPWAPKSYLEKVVAVYDYNKDKEDELSFQEGSIIYVIKKNDDGWYEGTMNGQTGLFPGNYVE 447 HSP 2 Score: 98.5969 bits (244), Expect = 2.876e-22 Identity = 50/112 (44.64%), Postives = 75/112 (66.96%), Query Frame = 1 Query: 157 RSLEQTVNYTAQALGSVAYKINLLATNFLEVLDKQNIKLNELQTKVNHLNMQVHIHQEKTARLSIGKYTMPRDPNVLKVSKVIEPLT-EIQGKYKRKEIDFSVLDNVGHGLK 489 R+LE+T YT Q+L SVAY+IN LA N L++LD Q +L ++++ +NH++ V IH+EK AR IG T + N + K++ P+ E +Y RK +D+S LD+VGHG+K Sbjct: 7 RALEETKAYTTQSLASVAYQINTLANNVLQMLDIQASQLRKMESSINHISQTVDIHKEKVARREIGILTT--NKNTSRTHKILAPVNPERPVRYVRKPVDYSALDDVGHGVK 116
BLAST of Abl interactor 2 vs. Ensembl Sea Lamprey
Match: ABI1 (abl interactor 1 [Source:HGNC Symbol;Acc:HGNC:11320]) HSP 1 Score: 101.679 bits (252), Expect = 3.092e-23 Identity = 46/80 (57.50%), Postives = 56/80 (70.00%), Query Frame = 1 Query: 1345 DDGWAPNQYICKVITLYEYQQNKDDELSFQEGELIYVVKKNNDGWWEGVMNGRTGLFPGNYVQNMN*SHN*FIIIFYYAD 1584 D WAP YI KV+ +Y+Y Q+KDDELSF EG +IYVV+KN+DGW+EG NG TGLFPGNYV+ I +YAD Sbjct: 385 DPEWAPKIYIEKVVAVYDYVQDKDDELSFHEGSIIYVVRKNDDGWYEGATNGHTGLFPGNYVEP----------IMHYAD 454 HSP 2 Score: 97.8265 bits (242), Expect = 5.050e-22 Identity = 49/112 (43.75%), Postives = 76/112 (67.86%), Query Frame = 1 Query: 157 RSLEQTVNYTAQALGSVAYKINLLATNFLEVLDKQNIKLNELQTKVNHLNMQVHIHQEKTARLSIGKYTMPRDPNVLKVSKVIEPLT-EIQGKYKRKEIDFSVLDNVGHGLK 489 ++LE+T YT Q+L SVAY+IN LA N L++LD Q +L ++++ +NH++ V IH+EK AR IG T + N + K++ P+ E +Y RK +DF+VLD++GHG+K Sbjct: 7 QALEETKAYTTQSLASVAYQINTLANNVLQMLDIQASQLGKMESAINHISQTVGIHKEKVARREIGILTT--NKNTTRTHKILAPVNPERPVRYVRKPLDFNVLDDIGHGMK 116
BLAST of Abl interactor 2 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000009021.1 (pep scaffold:Pmarinus_7.0:GL482604:596:7954:-1 gene:ENSPMAG00000008160.1 transcript:ENSPMAT00000009021.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 63.929 bits (154), Expect = 2.174e-11 Identity = 23/50 (46.00%), Postives = 37/50 (74.00%), Query Frame = 1 Query: 1393 YEYQQNKDDELSFQEGELIYVVKKNNDGWWEGVMNGRTGLFPGNYVQNMN 1542 +++Q+N +DELSF +G++I V + + GWWEG + GR+G FP NYV+ + Sbjct: 16 FDFQRNNEDELSFSKGDVITVTRPEDGGWWEGTLGGRSGWFPSNYVRELK 65
BLAST of Abl interactor 2 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000008112.1 (pep scaffold:Pmarinus_7.0:GL482163:8897:24902:-1 gene:ENSPMAG00000007333.1 transcript:ENSPMAT00000008112.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 61.6178 bits (148), Expect = 5.845e-11 Identity = 27/57 (47.37%), Postives = 40/57 (70.18%), Query Frame = 1 Query: 1375 CKVITLYEYQQNKDDELSFQEGELIYVVKKN--NDGWWEGVMNGRTGLFPGNYVQNM 1539 CK + YE Q N DELS +EGEL+ ++ K+ + GWWEG +NG+ G+FP N+V+ + Sbjct: 5 CKALFSYEAQNN--DELSLKEGELVEIIAKDCGDAGWWEGEVNGKRGVFPDNFVKLL 59
BLAST of Abl interactor 2 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000003067.1 (pep scaffold:Pmarinus_7.0:GL477025:38822:89389:-1 gene:ENSPMAG00000002795.1 transcript:ENSPMAT00000003067.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 62.7734 bits (151), Expect = 8.951e-11 Identity = 23/50 (46.00%), Postives = 35/50 (70.00%), Query Frame = 1 Query: 1393 YEYQQNKDDELSFQEGELIYVVKKNNDGWWEGVMNGRTGLFPGNYVQNMN 1542 + +Q+ +DELSF++G++I V + + GWWEG NG TG FP NYV+ + Sbjct: 175 FTFQRTNEDELSFEKGDVITVTRVEHGGWWEGAFNGHTGWFPSNYVRELK 224
BLAST of Abl interactor 2 vs. Ensembl Yeast
Match: LSB3 (Protein containing a C-terminal SH3 domain; binds Las17p, which is a homolog of human Wiskott-Aldrich Syndrome protein involved in actin patch assembly and actin polymerization; protein abundance increases in response to DNA replication stress; LSB3 has a paralog, YSC84, that arose from the whole genome duplication [Source:SGD;Acc:S000002968]) HSP 1 Score: 56.225 bits (134), Expect = 7.618e-9 Identity = 22/61 (36.07%), Postives = 40/61 (65.57%), Query Frame = 1 Query: 1357 APNQYICKVITLYEYQQNKDDELSFQEGELIYVVKKNN--DGWWEGVMNGRTGLFPGNYVQ 1533 +P+ K + LY + + +L F++G++I ++KK++ + WW G +NGR G+FP NYV+ Sbjct: 397 SPSTSSPKAVALYSFAGEESGDLPFRKGDVITILKKSDSQNDWWTGRVNGREGIFPANYVE 457
BLAST of Abl interactor 2 vs. Ensembl Yeast
Match: HSE1 (Subunit of the endosomal Vps27p-Hse1p complex; complex is required for sorting of ubiquitinated membrane proteins into intralumenal vesicles prior to vacuolar degradation, as well as for recycling of Golgi proteins and formation of lumenal membranes [Source:SGD;Acc:S000000994]) HSP 1 Score: 55.4546 bits (132), Expect = 1.258e-8 Identity = 22/53 (41.51%), Postives = 36/53 (67.92%), Query Frame = 1 Query: 1372 ICKVITLYEYQQNKDDELSFQEGELIYVVKKNNDGWWEGVMNGRTGLFPGNYV 1530 + +V LY+ N+ DELSF++G++I V+++ WW+G + G G+FP NYV Sbjct: 219 VRRVRALYDLTTNEPDELSFRKGDVITVLEQVYRDWWKGALRGNMGIFPLNYV 271
BLAST of Abl interactor 2 vs. Ensembl Yeast
Match: RVS167 (Calmodulin-binding actin-associated protein; roles in endocytic membrane tabulation and constriction, and exocytosis; N-BAR domain protein that interacts with Rvs161p to regulate actin cytoskeleton, endocytosis, and viability following starvation or osmotic stress; recruited to bud tips by Gyl1p and Gyp5p during polarized growth; homolog of mammalian amphiphysin [Source:SGD;Acc:S000002796]) HSP 1 Score: 53.1434 bits (126), Expect = 6.862e-8 Identity = 25/53 (47.17%), Postives = 33/53 (62.26%), Query Frame = 1 Query: 1381 VITLYEYQQNKDDELSFQEGELIYVVKKNND--GWWEGVMNGRTGLFPGNYVQ 1533 V LY+YQ +LSF G +I +V++ D WW G NG+ G+FPGNYVQ Sbjct: 426 VTALYDYQAQAAGDLSFPAGAVIEIVQRTPDVNEWWTGRYNGQQGVFPGNYVQ 478
BLAST of Abl interactor 2 vs. Ensembl Yeast
Match: YSC84 (Actin-binding protein; involved in bundling of actin filaments and endocytosis of actin cortical patches; activity stimulated by Las17p; contains SH3 domain similar to Rvs167p; YSC84 has a paralog, LSB3, that arose from the whole genome duplication [Source:SGD;Acc:S000001058]) HSP 1 Score: 51.9878 bits (123), Expect = 1.631e-7 Identity = 21/61 (34.43%), Postives = 38/61 (62.30%), Query Frame = 1 Query: 1357 APNQYICKVITLYEYQQNKDDELSFQEGELIYVVKKNN--DGWWEGVMNGRTGLFPGNYVQ 1533 A N + LY + + +L+F++G++I ++KK++ + WW G NG+ G+FP NYV+ Sbjct: 406 ATNSATPTAVALYNFAGEQPGDLAFKKGDVITILKKSDSQNDWWTGRTNGKEGIFPANYVR 466
BLAST of Abl interactor 2 vs. Ensembl Yeast
Match: PIN3 (Negative regulator of actin nucleation-promoting factor activity; interacts with Las17p, a homolog of human Wiskott-Aldrich Syndrome protein (WASP), via an N-terminal SH3 domain, and along with LSB1 cooperatively inhibits the nucleation of actin filaments; short-lived protein whose levels increase in response to thermal stress; induces the formation of the [PIN+] and [RNQ+] prions when overproduced; PIN3 has a paralog, LSB1, that arose from the whole genome duplication [Source:SGD;Acc:S000006358]) HSP 1 Score: 48.9062 bits (115), Expect = 4.606e-7 Identity = 19/51 (37.25%), Postives = 34/51 (66.67%), Query Frame = 1 Query: 1381 VITLYEYQQNKDDELSFQEGELIYVVKKNNDGWWEGVMNGRTGLFPGNYVQ 1533 V LY++ +D +L + G+ + +++K + W++G NGRTG+FP NYV+ Sbjct: 59 VEALYQFDPQQDGDLGLKPGDKVQLLEKLSPEWYKGSCNGRTGIFPANYVK 109
BLAST of Abl interactor 2 vs. Ensembl Nematostella
Match: EDO28105 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T7E6]) HSP 1 Score: 89.3521 bits (220), Expect = 8.607e-21 Identity = 53/160 (33.12%), Postives = 89/160 (55.62%), Query Frame = 1 Query: 61 LLKEDIPNGTEDLINTSKTLEDVADHCLLTYDRS--------------------LEQTVNYTAQALGSVAYKINLLATNFLEVLDKQNIKLNELQTKVNHLNMQVHIHQEKTARLSIGKYTMPRDPNVLKVSKVIEPLTEIQ-GKYKRKEIDFSVLDNVG 477 L++++IP G + L + + L VA++C Y L++T +T Q+L SVAY+IN LA N L +LD+Q +L +++K+N+++ V+IH+EK AR IG + N + K+I P + + +Y RK ID+S+LD++G Sbjct: 11 LIEKEIPEGRQALRDGHENLARVANYCQQKYSDCSNRYKTSPDKKKVLEESKAVLDETKQFTTQSLASVAYQINSLAVNMLNLLDQQVSQLQTMESKINYISETVNIHKEKVARREIG--VLATSKNTSRTHKIIAPAKQEKPERYSRKPIDYSILDDIG 168
BLAST of Abl interactor 2 vs. Ensembl Nematostella
Match: EDO33141 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7ST28]) HSP 1 Score: 88.5817 bits (218), Expect = 1.376e-20 Identity = 52/160 (32.50%), Postives = 88/160 (55.00%), Query Frame = 1 Query: 61 LLKEDIPNGTEDLINTSKTLEDVADHCLLTYDRS--------------------LEQTVNYTAQALGSVAYKINLLATNFLEVLDKQNIKLNELQTKVNHLNMQVHIHQEKTARLSIGKYTMPRDPNVLKVSKVIEPLTEIQ-GKYKRKEIDFSVLDNVG 477 L++++IP G + L + + L VA++C Y ++T +T Q+L SVAY+IN LA N L +LD+Q +L +++K+N+++ V+IH+EK AR IG + N + K+I P + + +Y RK ID+S+LD++G Sbjct: 4 LIEKEIPEGRQALRDGHENLAKVANYCQQKYSDCSNRYKTSPDKKKVLEESKAVFDETKQFTTQSLASVAYQINSLAVNMLNLLDQQVSQLQTMESKINYISETVNIHKEKIARREIG--VLATSKNTSRTHKIIAPAKQEKPERYSRKPIDYSILDDIG 161
BLAST of Abl interactor 2 vs. Ensembl Nematostella
Match: EDO38147 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SDP5]) HSP 1 Score: 82.0333 bits (201), Expect = 4.762e-19 Identity = 37/63 (58.73%), Postives = 48/63 (76.19%), Query Frame = 1 Query: 1348 DGWAPNQYICKVITLYEYQQNKDDELSFQEGELIYVVKKNNDGWWEGV-MNGRTGLFPGNYVQ 1533 DG P ++ KVI LY+Y +DDEL+F E +IYV+KKN+DGW+EGV +G TGLFPGNYV+ Sbjct: 36 DGGVPADFLEKVIALYDYNATRDDELTFAENTIIYVIKKNDDGWYEGVTTDGLTGLFPGNYVE 98
BLAST of Abl interactor 2 vs. Ensembl Nematostella
Match: EDO38999 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SBA8]) HSP 1 Score: 63.929 bits (154), Expect = 1.432e-10 Identity = 27/61 (44.26%), Postives = 41/61 (67.21%), Query Frame = 1 Query: 1369 YICKVITLYEYQQNKDDELSFQEGELIYVVKKN----NDGWWEGVMNGRTGLFPGNYVQNM 1539 Y+C V LY+Y+ D+ELSF EG+ IYV K++ +DG+WEG ++G G+FP V+ + Sbjct: 650 YLCMVRALYDYEAMSDEELSFNEGDTIYVTKQDDHGVDDGFWEGYIDGHKGVFPSLVVEEI 710
BLAST of Abl interactor 2 vs. Ensembl Nematostella
Match: EDO42689 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S0K6]) HSP 1 Score: 60.4622 bits (145), Expect = 9.379e-10 Identity = 25/54 (46.30%), Postives = 38/54 (70.37%), Query Frame = 1 Query: 1381 VITLYEYQQNKDDELSFQEGELIYVVKKNND-GWWEGVMNGRTGLFPGNYVQNM 1539 V+ LY+Y+ +DDELSF+ GE++ + + +D GW G +N RTGLFP YV+ + Sbjct: 386 VLALYDYEAAEDDELSFKAGEIVTKLSERDDQGWCRGRINHRTGLFPAEYVEAL 439
BLAST of Abl interactor 2 vs. Ensembl Medaka
Match: abi2b (abl interactor 2 [Source:NCBI gene;Acc:101169339]) HSP 1 Score: 118.627 bits (296), Expect = 3.668e-29 Identity = 64/151 (42.38%), Postives = 95/151 (62.91%), Query Frame = 1 Query: 58 ILLKEDIPNGTEDLINTSKTLEDVADHCLLTY------DRSLEQTVNYTAQALGSVAYKINLLATNFLEVLDKQNIKLNELQTKVNHLNMQVHIHQEKTARLSIGKYTMPRDPNVLKVSKVIEPLT-EIQGKYKRKEIDFSVLDNVGHGLK 489 +LL+E+IP G L+++ LE VA++C Y R+LE+T NYT Q+L SVAY IN LA N L++LD Q +L +++ +NH++ V IH+EK AR IG T + N + K+I P E +Y RK +D+S+LD++GHG+K Sbjct: 37 MLLEEEIPAGRSALLDSFTNLERVAEYCESNYVQSPDKQRALEETKNYTTQSLASVAYLINTLANNVLQMLDIQASQLRRMESSINHISQTVDIHKEKVARREIGILTT--NKNTSRTHKIIAPANPERPVRYIRKPVDYSLLDDMGHGVK 185
BLAST of Abl interactor 2 vs. Ensembl Medaka
Match: abi2b (abl interactor 2 [Source:NCBI gene;Acc:101169339]) HSP 1 Score: 118.242 bits (295), Expect = 5.872e-28 Identity = 64/151 (42.38%), Postives = 95/151 (62.91%), Query Frame = 1 Query: 58 ILLKEDIPNGTEDLINTSKTLEDVADHCLLTY------DRSLEQTVNYTAQALGSVAYKINLLATNFLEVLDKQNIKLNELQTKVNHLNMQVHIHQEKTARLSIGKYTMPRDPNVLKVSKVIEPLT-EIQGKYKRKEIDFSVLDNVGHGLK 489 +LL+E+IP G L+++ LE VA++C Y R+LE+T NYT Q+L SVAY IN LA N L++LD Q +L +++ +NH++ V IH+EK AR IG T + N + K+I P E +Y RK +D+S+LD++GHG+K Sbjct: 6 MLLEEEIPAGRSALLDSFTNLERVAEYCESNYVQSPDKQRALEETKNYTTQSLASVAYLINTLANNVLQMLDIQASQLRRMESSINHISQTVDIHKEKVARREIGILTT--NKNTSRTHKIIAPANPERPVRYIRKPVDYSLLDDMGHGVK 154 HSP 2 Score: 106.686 bits (265), Expect = 3.618e-24 Identity = 46/83 (55.42%), Postives = 62/83 (74.70%), Query Frame = 1 Query: 1336 SQVDDGWAPNQYICKVITLYEYQQNKDDELSFQEGELIYVVKKNNDGWWEGVMNGRTGLFPGNYVQNMN*SHN*FIIIFYYAD 1584 ++ D WAP Y+ KV+ +Y+Y ++K+DELSFQEG +IYV+KKN+DGW+EGVMNG TGLFPGNYV++ I +YAD Sbjct: 411 AEEDPPWAPRTYMEKVVAIYDYTRDKEDELSFQEGSIIYVIKKNDDGWFEGVMNGTTGLFPGNYVES----------IMHYAD 483
BLAST of Abl interactor 2 vs. Ensembl Medaka
Match: ENSORLT00000017876.2 (abl interactor 2 [Source:NCBI gene;Acc:101175519]) HSP 1 Score: 117.472 bits (293), Expect = 9.796e-28 Identity = 65/152 (42.76%), Postives = 96/152 (63.16%), Query Frame = 1 Query: 58 ILLKEDIPNGTEDLINTSKTLEDVADHCLLTYDRS------LEQTVNYTAQALGSVAYKINLLATNFLEVLDKQNIKLNELQTKVNHLNMQVHIHQEKTARLSIGKYTMPRDPNVLKVSKVIEPLT-EIQGKYKRKEIDFSVLDNVGHGLKE 492 +LL+E+IP G L+++ LE VA++C Y +S LE+T NYT Q+L SVAY IN LA N L++LD Q +L +++ VNH++ V IH+EK AR IG T + N + K++ P E +Y RK ID++VLD++GHG+K+ Sbjct: 6 MLLEEEIPAGRRALLDSFTNLERVAEYCESNYVQSADKQQALEETKNYTTQSLASVAYLINTLANNVLQMLDIQASQLRRMESSVNHISQTVDIHKEKVARREIGILTT--NKNTCRSHKIVAPSNPERPVRYIRKPIDYNVLDDIGHGVKQ 155 HSP 2 Score: 104.375 bits (259), Expect = 2.131e-23 Identity = 46/83 (55.42%), Postives = 59/83 (71.08%), Query Frame = 1 Query: 1336 SQVDDGWAPNQYICKVITLYEYQQNKDDELSFQEGELIYVVKKNNDGWWEGVMNGRTGLFPGNYVQNMN*SHN*FIIIFYYAD 1584 ++ D WAP Y+ KV+ +Y+Y +K+DELSFQEG +IYVVKKN DGW+EGVMN TGLFPGNYV++ I +YAD Sbjct: 392 AEEDPPWAPRSYVEKVVAIYDYTADKEDELSFQEGAIIYVVKKNEDGWFEGVMNATTGLFPGNYVES----------IMHYAD 464
BLAST of Abl interactor 2 vs. Ensembl Medaka
Match: ABI1 (abl interactor 1 [Source:NCBI gene;Acc:101170628]) HSP 1 Score: 115.546 bits (288), Expect = 4.304e-27 Identity = 62/152 (40.79%), Postives = 94/152 (61.84%), Query Frame = 1 Query: 58 ILLKEDIPNGTEDLINTSKTLEDVADHCLLTY------DRSLEQTVNYTAQALGSVAYKINLLATNFLEVLDKQNIKLNELQTKVNHLNMQVHIHQEKTARLSIGKYTMPRDPNVLKVSKVIEPL-TEIQGKYKRKEIDFSVLDNVGHGLKE 492 +LL E+IP G L+ + + L VAD+C Y ++LE+T YT Q+L SVAY+IN LA N L++LD Q +L +++ +NH++ V IH+EK AR IG T + N + K++ P E +Y RK +D++VLD+VGHG+K+ Sbjct: 6 MLLDEEIPAGKRALVESYQNLTRVADYCENNYVQAEDKRKALEETKAYTTQSLASVAYQINALANNVLQLLDIQASQLRRMESSINHISQTVDIHKEKVARREIGILTT--NKNTTRTHKIVAPANIERPVRYIRKPVDYTVLDDVGHGIKQ 155 HSP 2 Score: 99.7525 bits (247), Expect = 6.291e-22 Identity = 46/80 (57.50%), Postives = 57/80 (71.25%), Query Frame = 1 Query: 1345 DDGWAPNQYICKVITLYEYQQNKDDELSFQEGELIYVVKKNNDGWWEGVMNGRTGLFPGNYVQNMN*SHN*FIIIFYYAD 1584 D WAP YI KV+ +Y+Y ++K+DELSF EG +IYVVKKN+DGW+EGV NG TGLFPGNYV+ I +YAD Sbjct: 396 DPQWAPKNYIEKVVAIYDYAKDKNDELSFLEGAIIYVVKKNDDGWFEGVSNGVTGLFPGNYVEP----------IMHYAD 465
BLAST of Abl interactor 2 vs. Ensembl Medaka
Match: ABI1 (abl interactor 1 [Source:NCBI gene;Acc:101170628]) HSP 1 Score: 116.701 bits (291), Expect = 4.605e-27 Identity = 62/152 (40.79%), Postives = 94/152 (61.84%), Query Frame = 1 Query: 58 ILLKEDIPNGTEDLINTSKTLEDVADHCLLTY------DRSLEQTVNYTAQALGSVAYKINLLATNFLEVLDKQNIKLNELQTKVNHLNMQVHIHQEKTARLSIGKYTMPRDPNVLKVSKVIEPLT-EIQGKYKRKEIDFSVLDNVGHGLKE 492 +LL E+IP G L+ + + L VAD+C Y ++LE+T YT Q+L SVAY+IN LA N L++LD Q +L +++ +NH++ V IH+EK AR IG T + N + K++ P E +Y RK +D++VLD+VGHG+K+ Sbjct: 6 MLLDEEIPAGKRALVESYQNLTRVADYCENNYVQAEDKRKALEETKAYTTQSLASVAYQINALANNVLQLLDIQASQLRRMESSINHISQTVDIHKEKVARREIGILTT--NKNTTRTHKIVAPANIERPVRYIRKPVDYTVLDDVGHGIKQ 155
BLAST of Abl interactor 2 vs. Planmine SMEST
Match: SMESG000055438.1 (SMESG000055438.1) HSP 1 Score: 826.624 bits (2134), Expect = 0.000e+0 Identity = 505/506 (99.80%), Postives = 505/506 (99.80%), Query Frame = 1 Query: 25 MGTEFLPKDYIILLKEDIPNGTEDLINTSKTLEDVADHCLLTYDRSLEQTVNYTAQALGSVAYKINLLATNFLEVLDKQNIKLNELQTKVNHLNMQVHIHQEKTARLSIGKYTMPRDPNVLKVSKVIEPLTEIQGKYKRKEIDFSVLDNVGHGLKEPQLGTSGVFXXXXXXXXXXXXXXXXXXXVYTHSNIGGSISSKAVPDYMKLGKAQTIGRTGGLNINNPSNTIYRAPANLTQRSQIPMPSPNLNSGNGMAAPQALNYGNTMQYXXXXXXXXXXXXXXXXXXXXXXXXXXXKQYQPPANVVSPHKMSVGSIQGNTPPYGYSGMNHPMAHIXXXXXXVVTNQQEQNISPMMRXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXVDQFQRPVNNEQFQRLPNNEQEYIDKNQGRYISDTVGIAHLQPNPYDVLRVKSQVDDGWAPNQYICKVITLYEYQQNKDDELSFQEGELIYVVKKNNDGWWEGVMNGRTGLFPGNYVQNMN 1542 MGTEFLPKDYIILLKEDIPNGTEDLINTSKTLEDVADHCLLTYDRSLEQTVNYTAQALGSVAYKINLLATNFLEVLDKQNIKLNELQTKVNHLNMQVHIHQEKTARLSIGKYTMPRDPNVLKVSKVIEPLTEIQGKYKRKEIDFSVLDNVGHGLKEPQLGTSGVFSNTSRRSSTSGSDTHSSSHVYTHSNIGGSISSKAVPDYMKLGKAQTIGRTGGLNINNPSNTIYRAPANLTQRSQIPMPSPNLNSGNGMAAPQALNYGNTMQYQQQISQGTRRSSSTSTSTSGSTQMQQQKQYQPPANVVSPHKMSVGSIQGNTPPYGYSGMNHPMAHIPPPPPPVVTNQQEQNISPMMRYNELPPPPLEPPSPYQQQSQQNMNMLPPPPNVDQFQRPVNNEQFQR PNNEQEYIDKNQGRYISDTVGIAHLQPNPYDVLRVKSQVDDGWAPNQYICKVITLYEYQQNKDDELSFQEGELIYVVKKNNDGWWEGVMNGRTGLFPGNYVQNMN Sbjct: 1 MGTEFLPKDYIILLKEDIPNGTEDLINTSKTLEDVADHCLLTYDRSLEQTVNYTAQALGSVAYKINLLATNFLEVLDKQNIKLNELQTKVNHLNMQVHIHQEKTARLSIGKYTMPRDPNVLKVSKVIEPLTEIQGKYKRKEIDFSVLDNVGHGLKEPQLGTSGVFSNTSRRSSTSGSDTHSSSHVYTHSNIGGSISSKAVPDYMKLGKAQTIGRTGGLNINNPSNTIYRAPANLTQRSQIPMPSPNLNSGNGMAAPQALNYGNTMQYQQQISQGTRRSSSTSTSTSGSTQMQQQKQYQPPANVVSPHKMSVGSIQGNTPPYGYSGMNHPMAHIPPPPPPVVTNQQEQNISPMMRYNELPPPPLEPPSPYQQQSQQNMNMLPPPPNVDQFQRPVNNEQFQRPPNNEQEYIDKNQGRYISDTVGIAHLQPNPYDVLRVKSQVDDGWAPNQYICKVITLYEYQQNKDDELSFQEGELIYVVKKNNDGWWEGVMNGRTGLFPGNYVQNMN 506
BLAST of Abl interactor 2 vs. Planmine SMEST
Match: SMESG000055438.1 (SMESG000055438.1) HSP 1 Score: 818.92 bits (2114), Expect = 0.000e+0 Identity = 501/506 (99.01%), Postives = 504/506 (99.60%), Query Frame = 1 Query: 25 MGTEFLPKDYIILLKEDIPNGTEDLINTSKTLEDVADHCLLTYDRSLEQTVNYTAQALGSVAYKINLLATNFLEVLDKQNIKLNELQTKVNHLNMQVHIHQEKTARLSIGKYTMPRDPNVLKVSKVIEPLTEIQGKYKRKEIDFSVLDNVGHGLKEPQLGTSGVFXXXXXXXXXXXXXXXXXXXVYTHSNIGGSISSKAVPDYMKLGKAQTIGRTGGLNINNPSNTIYRAPANLTQRSQIPMPSPNLNSGNGMAAPQALNYGNTMQYXXXXXXXXXXXXXXXXXXXXXXXXXXXKQYQPPANVVSPHKMSVGSIQGNTPPYGYSGMNHPMAHIXXXXXXVVTNQQEQNISPMMRXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXVDQFQRPVNNEQFQRLPNNEQEYIDKNQGRYISDTVGIAHLQPNPYDVLRVKSQVDDGWAPNQYICKVITLYEYQQNKDDELSFQEGELIYVVKKNNDGWWEGVMNGRTGLFPGNYVQNMN 1542 MGTEFLPKDYIILLKEDIPNGTEDLINTSKTLEDVADHCLLTYDRSLEQTVNYTAQALGSVAYKINLLATNFLEVLDKQNIKLNELQTKVNHLNMQVHIHQEKTARLSIGKYTMPRDPNVLKVSKVIEPLTEIQGKYKRKEIDFSVLDNVGHGLKEPQLGTSGVFSNTSRRSSTSGSDTHSSSHVYTHSNIGGSISSKAVPDYMKLGKAQTIGRTGGLNINNPSNTIYRAPANLTQRSQIPMPSPNLNSGNGMAAPQALNYGNTMQYQQQISQGTRRSSSTSTSTSGSTQMQQQKQYQPPANVVSPHKMSVGSIQGNTPPYGYSGMNHPMAHIPPPPPPVVTNQQEQNISPMMRYNELPPPPLEPPSPYQQQSQQNMNMLPPPPNVDQFQRPVNNEQFQR PNNEQEYIDKNQGRYISDTVGIAHLQPNPYDVLRVKSQVDDGWAPNQYICKVITL++Y+QNKDDELSFQEGELIYVVKKN DGWWEGVMNGRTGLFPGNYVQNMN Sbjct: 1 MGTEFLPKDYIILLKEDIPNGTEDLINTSKTLEDVADHCLLTYDRSLEQTVNYTAQALGSVAYKINLLATNFLEVLDKQNIKLNELQTKVNHLNMQVHIHQEKTARLSIGKYTMPRDPNVLKVSKVIEPLTEIQGKYKRKEIDFSVLDNVGHGLKEPQLGTSGVFSNTSRRSSTSGSDTHSSSHVYTHSNIGGSISSKAVPDYMKLGKAQTIGRTGGLNINNPSNTIYRAPANLTQRSQIPMPSPNLNSGNGMAAPQALNYGNTMQYQQQISQGTRRSSSTSTSTSGSTQMQQQKQYQPPANVVSPHKMSVGSIQGNTPPYGYSGMNHPMAHIPPPPPPVVTNQQEQNISPMMRYNELPPPPLEPPSPYQQQSQQNMNMLPPPPNVDQFQRPVNNEQFQRPPNNEQEYIDKNQGRYISDTVGIAHLQPNPYDVLRVKSQVDDGWAPNQYICKVITLHKYEQNKDDELSFQEGELIYVVKKNIDGWWEGVMNGRTGLFPGNYVQNMN 506
BLAST of Abl interactor 2 vs. Planmine SMEST
Match: SMESG000032406.1 (SMESG000032406.1) HSP 1 Score: 62.3882 bits (150), Expect = 8.566e-11 Identity = 26/59 (44.07%), Postives = 40/59 (67.80%), Query Frame = 1 Query: 1363 NQYICKVITLYEYQQNKDDELSFQEGELIYVVKKNNDGWWEGVMNGRTGLFPGNYVQNM 1539 N+ CK L++++ +ELSFQEG++I + +K ND WWEG +NG+ GL P +YV + Sbjct: 165 NREKCKA--LHDFEARDQEELSFQEGDVITIKRKINDIWWEGELNGKIGLIPKDYVNEL 221
BLAST of Abl interactor 2 vs. Planmine SMEST
Match: SMESG000073128.1 (SMESG000073128.1) HSP 1 Score: 59.3066 bits (142), Expect = 6.688e-9 Identity = 25/51 (49.02%), Postives = 36/51 (70.59%), Query Frame = 1 Query: 1381 VITLYEYQQNKDDELSFQEGELIYVVKKNNDGWWEG-VMNGRTGLFPGNYV 1530 V+ +Y Y +DDE+SF+EGE IY V + ++GWW+G +G G+FP NYV Sbjct: 645 VVAVYSYHALQDDEISFEEGEHIYNVNQIDEGWWQGETKDGDKGMFPSNYV 695 HSP 2 Score: 52.373 bits (124), Expect = 8.182e-7 Identity = 26/78 (33.33%), Postives = 42/78 (53.85%), Query Frame = 1 Query: 1303 QPNPYDVLRVKSQVDDGWAPNQYICKVITLYEYQQNKDDELSFQEGELIYVVKKNNDGWWEGV-MNGRTGLFPGNYVQ 1533 Q N D V + D P K + +EY+ DE+ F+ GE+I +++ ++GWW G +G+ G+FP NYV+ Sbjct: 535 QNNKIDTKSVHLENQDTKTPKTKSAKAV--FEYECQDSDEIDFEVGEIITDIEEIDEGWWIGCNKSGKRGMFPSNYVE 610
BLAST of Abl interactor 2 vs. Planmine SMEST
Match: SMESG000068232.1 (SMESG000068232.1) HSP 1 Score: 58.9214 bits (141), Expect = 1.100e-8 Identity = 24/54 (44.44%), Postives = 36/54 (66.67%), Query Frame = 1 Query: 1378 KVITLYEYQQNKDDELSFQEGELIYVVKKNNDGWWEGVMNGRTGLFPGNYVQNM 1539 +V LY Y+ DELS G++I +V+++N+GWW G + RTGL P NYV+ + Sbjct: 1050 RVEALYAYEATDTDELSIYPGDIIELVREDNEGWWTGKIGNRTGLIPSNYVKKI 1103 The following BLAST results are available for this feature:
BLAST of Abl interactor 2 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of Abl interactor 2 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of Abl interactor 2 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of Abl interactor 2 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of Abl interactor 2 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of Abl interactor 2 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of Abl interactor 2 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of Abl interactor 2 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Abl interactor 2 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of Abl interactor 2 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 5
BLAST of Abl interactor 2 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 5
BLAST of Abl interactor 2 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of Abl interactor 2 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of Abl interactor 2 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30028026 ID=SMED30028026|Name=Abl interactor 2|organism=Schmidtea mediterranea sexual|type=transcript|length=1793bpback to top protein sequence of SMED30028026-orf-1 >SMED30028026-orf-1 ID=SMED30028026-orf-1|Name=SMED30028026-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=507bp MGTEFLPKDYIILLKEDIPNGTEDLINTSKTLEDVADHCLLTYDRSLEQTback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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