Phosphodiesterase

Overview
NamePhosphodiesterase
Smed IDSMED30027985
Length (bp)1248
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Phosphodiesterase (SMED30027985) t-SNE clustered cells

Violin plots show distribution of expression levels for Phosphodiesterase (SMED30027985) in cells (dots) of each of the 12 neoblast clusters.

 

back to top

 

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

back to top
Anatomical Expression

PAGE et. al., 2020



SMED30027985

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 10

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
X1 cellSMED30027985h1SMcG0005102 SmedASXL_012545SmedAsxl_ww_GCZZ01PMID:26114597
Zhu et al., 2015		FACS sorted cell population asexual adult RNA-sequencing evidence
testisSMED30027985h1SMcG0005102 DN313728.1smed_ncbi_20240424PMID:22074376
Chong et al., 2011		whole organism adult hermaphrodite fluorescence in situ hybridization evidence
spermatogoniumSMED30027985h1SMcG0005102 DN313728.1smed_ncbi_20240424PMID:22074376
Chong et al., 2011		whole organism adult hermaphrodite fluorescence in situ hybridization evidence
spermatocyteSMED30027985h1SMcG0005102 DN313728.1smed_ncbi_20240424PMID:22074376
Chong et al., 2011		whole organism adult hermaphrodite fluorescence in situ hybridization evidence
spermatidSMED30027985h1SMcG0005102 DN313728.1smed_ncbi_20240424PMID:22074376
Chong et al., 2011		whole organism adult hermaphrodite fluorescence in situ hybridization evidence
reproductive organSMED30027985h1SMcG0005102 Contig29107uc_Smed_v2PMID:28434803
Rouhana et al., 2017		whole organism adult hermaphrodite RNA-sequencing evidence
reproductive organSMED30027985h1SMcG0005102 Contig29107newmark_estsPMID:28434803
Rouhana et al., 2017		whole organism adult hermaphrodite RNA-sequencing evidence
testisSMED30027985h1SMcG0005102 PL08006B2E03smed_ncbi_20240424PMID:28434803
Rouhana et al., 2017		whole organism adult hermaphrodite colorimetric in situ hybridization evidence
copulatory apparatusSMED30027985h1SMcG0005102 PL08006B2E03smed_ncbi_20240424PMID:28434803
Rouhana et al., 2017		whole organism adult hermaphrodite colorimetric in situ hybridization evidence
testis primordiumSMED30027985h1SMcG0005102 PL08006B2E03_SE3GPL10652PMID:20844018
Wang et al., 2010		whole organism juvenile stagecDNA to DNA expression microarray evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Phosphodiesterase vs. Ensembl Human
Match: PDE7A (phosphodiesterase 7A [Source:HGNC Symbol;Acc:HGNC:8791])

HSP 1 Score: 301.212 bits (770), Expect = 7.112e-98
Identity = 142/334 (42.51%), Postives = 215/334 (64.37%), Query Frame = 3 
Query:   93 VLDSEYFGIDKKRQLLLLKSVRWNYDIFTLDRITSGHPIVHLGMFLFEYHNLLTSFKIDYLKFLHTLTLLENNYHQKNPYHNALHAADVTQAMHCYVSDSKIRQKMKQFDFMVSLLGAMFHDVDHPGVNQAFLEKTNNYLSEFYKAQSVLENHHYRMALSILHETRVFHHFTTKQWGELQYRMYKLIMATDIARQNEYLDQFTNFIEQNIGIKEAFTKENKILIMQMALKCADICNPCREWRVAACWANLISAEFFRQGDRERRMNLPLAPTMDRYGITKPKVQTGFIRFLVRPLFNKWNEFMKTRLSEKMVQQLEQNLLRWELKQNQMAEKSD 1094
            +LD +Y G   + + +L K   WN+DIF  DR+T+G+ +V L   LF  H L+  F +D +K    L +++ +YH +NPYHNA+HAADVTQAMHCY+ + K+   +  +D ++SL+ A  HD+DHPGVNQ FL KTN+YL+  YK  SVLENHH+R A+ +L E+ +F H   +   +++ ++  LI+ATDI+RQNEYL  F + +++     E     ++ L++QMALKCADICNPCR W ++  W+  ++ EFF QGD E++ +L ++P  DR+  +   +Q GF+ +LV PLF +W  F  TRLS+ M+  +  N   W+  Q + +   D
Sbjct:  109 ILDDDYNG---QAKCMLEKVGNWNFDIFLFDRLTNGNSLVSLTFHLFSLHGLIEYFHLDMMKLRRFLVMIQEDYHSQNPYHNAVHAADVTQAMHCYLKEPKLANSVTPWDILLSLIAAATHDLDHPGVNQPFLIKTNHYLATLYKNTSVLENHHWRSAVGLLRESGLFSHLPLESRQQMETQIGALILATDISRQNEYLSLFRSHLDRGDLCLE--DTRHRHLVLQMALKCADICNPCRTWELSKQWSEKVTEEFFHQGDIEKKYHLGVSPLCDRHTESIANIQIGFMTYLVEPLFTEWARFSNTRLSQTMLGHVGLNKASWKGLQREQSSSED 437
[Close]
BLAST of Phosphodiesterase vs. Ensembl Human
Match: PDE7A (phosphodiesterase 7A [Source:HGNC Symbol;Acc:HGNC:8791])

HSP 1 Score: 301.212 bits (770), Expect = 1.692e-97
Identity = 142/334 (42.51%), Postives = 215/334 (64.37%), Query Frame = 3 
Query:   93 VLDSEYFGIDKKRQLLLLKSVRWNYDIFTLDRITSGHPIVHLGMFLFEYHNLLTSFKIDYLKFLHTLTLLENNYHQKNPYHNALHAADVTQAMHCYVSDSKIRQKMKQFDFMVSLLGAMFHDVDHPGVNQAFLEKTNNYLSEFYKAQSVLENHHYRMALSILHETRVFHHFTTKQWGELQYRMYKLIMATDIARQNEYLDQFTNFIEQNIGIKEAFTKENKILIMQMALKCADICNPCREWRVAACWANLISAEFFRQGDRERRMNLPLAPTMDRYGITKPKVQTGFIRFLVRPLFNKWNEFMKTRLSEKMVQQLEQNLLRWELKQNQMAEKSD 1094
            +LD +Y G   + + +L K   WN+DIF  DR+T+G+ +V L   LF  H L+  F +D +K    L +++ +YH +NPYHNA+HAADVTQAMHCY+ + K+   +  +D ++SL+ A  HD+DHPGVNQ FL KTN+YL+  YK  SVLENHH+R A+ +L E+ +F H   +   +++ ++  LI+ATDI+RQNEYL  F + +++     E     ++ L++QMALKCADICNPCR W ++  W+  ++ EFF QGD E++ +L ++P  DR+  +   +Q GF+ +LV PLF +W  F  TRLS+ M+  +  N   W+  Q + +   D
Sbjct:  135 ILDDDYNG---QAKCMLEKVGNWNFDIFLFDRLTNGNSLVSLTFHLFSLHGLIEYFHLDMMKLRRFLVMIQEDYHSQNPYHNAVHAADVTQAMHCYLKEPKLANSVTPWDILLSLIAAATHDLDHPGVNQPFLIKTNHYLATLYKNTSVLENHHWRSAVGLLRESGLFSHLPLESRQQMETQIGALILATDISRQNEYLSLFRSHLDRGDLCLE--DTRHRHLVLQMALKCADICNPCRTWELSKQWSEKVTEEFFHQGDIEKKYHLGVSPLCDRHTESIANIQIGFMTYLVEPLFTEWARFSNTRLSQTMLGHVGLNKASWKGLQREQSSSED 463
[Close]
BLAST of Phosphodiesterase vs. Ensembl Human
Match: PDE7B (phosphodiesterase 7B [Source:HGNC Symbol;Acc:HGNC:8792])

HSP 1 Score: 275.404 bits (703), Expect = 6.434e-88
Identity = 136/349 (38.97%), Postives = 216/349 (61.89%), Query Frame = 3 
Query:   93 VLDSEYFGIDKKRQLLLLKSVRWNYDIFTLDRITSGHPIVHLGMFLFEYHNLLTSFKIDYLKFLHTLTLLENNYHQKNPYHNALHAADVTQAMHCYVSDSKIRQKMKQFDFMVSLLGAMFHDVDHPGVNQAFLEKTNNYLSEFYKAQSVLENHHYRMALSILHETRVFHHFTTKQWGELQYRMYKLIMATDIARQNEYLDQFTNFI-EQNIGIKEAFTKENKILIMQMALKCADICNPCREWRVAACWANLISAEFFRQGDRERRMNLPLAPTMDRYGITKPKVQTGFIRFLVRPLFNKWNEFM-KTRLSEKMVQQLEQNLLRWE--LKQNQMAEKSDMLGEDAKPVSQ 1127
            +LD +Y G   + + +L K   W++DIF  DR+T+G+ +V L   LF  H L+  FK+D +     L +++ +YH +NPYHNA+HAADVTQAMHCY+ + K+   +   D M+ LL A  HDVDHPGVNQ FL KTN++L+  Y+  SVLENHH+R  + +L E+R+  H   +   +++ ++  LI+ATDI RQNE+L +    +  +++ +++A   +++  ++Q+ALKCADICNPCR W ++  W+  +  EF+RQG+ E++  L ++P  ++   + P +Q GF+ ++V PLF +W  F   + LSE M+  L  N  +W+  L +   +  S   G D     Q
Sbjct:   96 LLDEDYLG---QARHMLSKVGMWDFDIFLFDRLTNGNSLVTLLCHLFNTHGLIHHFKLDMVTLHRFLVMVQEDYHSQNPYHNAVHAADVTQAMHCYLKEPKLASFLTPLDIMLGLLAAAAHDVDHPGVNQPFLIKTNHHLANLYQNMSVLENHHWRSTIGMLRESRLLAHLPKEMTQDIEQQLGSLILATDINRQNEFLTRLKAHLHNKDLRLEDA---QDRHFMLQIALKCADICNPCRIWEMSKQWSERVCEEFYRQGELEQKFELEISPLCNQQKDSIPSIQIGFMSYIVEPLFREWAHFTGNSTLSENMLGHLAHNKAQWKSLLPRQHRSRGSSGSGPDHDHAGQ 438
[Close]
BLAST of Phosphodiesterase vs. Ensembl Human
Match: PDE7B (phosphodiesterase 7B [Source:HGNC Symbol;Acc:HGNC:8792])

HSP 1 Score: 274.633 bits (701), Expect = 5.178e-87
Identity = 135/343 (39.36%), Postives = 215/343 (62.68%), Query Frame = 3 
Query:   93 VLDSEYFGIDKKRQLLLLKSVRWNYDIFTLDRITSGHPIVHLGMFLFEYHNLLTSFKIDYLKFLHTLTLLENNYHQKNPYHNALHAADVTQAMHCYVSDSKIRQKMKQFDFMVSLLGAMFHDVDHPGVNQAFLEKTNNYLSEFYKAQSVLENHHYRMALSILHETRVFHHFTTKQWGELQYRMYKLIMATDIARQNEYLDQFTNFI-EQNIGIKEAFTKENKILIMQMALKCADICNPCREWRVAACWANLISAEFFRQGDRERRMNLPLAPTMDRYGITKPKVQTGFIRFLVRPLFNKWNEFM-KTRLSEKMVQQLEQNLLRWE--LKQNQMAEKSDMLGED 1109
            +LD +Y G   + + +L K   W++DIF  DR+T+G+ +V L   LF  H L+  FK+D +     L +++ +YH +NPYHNA+HAADVTQAMHCY+ + K+   +   D M+ LL A  HDVDHPGVNQ FL KTN++L+  Y+  SVLENHH+R  + +L E+R+  H   +   +++ ++  LI+ATDI RQNE+L +    +  +++ +++A   +++  ++Q+ALKCADICNPCR W ++  W+  +  EF+RQG+ E++  L ++P  ++   + P +Q GF+ ++V PLF +W  F   + LSE M+  L  N  +W+  L +   +  S   G D
Sbjct:  148 LLDEDYLG---QARHMLSKVGMWDFDIFLFDRLTNGNSLVTLLCHLFNTHGLIHHFKLDMVTLHRFLVMVQEDYHSQNPYHNAVHAADVTQAMHCYLKEPKLASFLTPLDIMLGLLAAAAHDVDHPGVNQPFLIKTNHHLANLYQNMSVLENHHWRSTIGMLRESRLLAHLPKEMTQDIEQQLGSLILATDINRQNEFLTRLKAHLHNKDLRLEDA---QDRHFMLQIALKCADICNPCRIWEMSKQWSERVCEEFYRQGELEQKFELEISPLCNQQKDSIPSIQIGFMSYIVEPLFREWAHFTGNSTLSENMLGHLAHNKAQWKSLLPRQHRSRGSSGSGPD 484
[Close]
BLAST of Phosphodiesterase vs. Ensembl Human
Match: PDE7A (phosphodiesterase 7A [Source:HGNC Symbol;Acc:HGNC:8791])

HSP 1 Score: 266.159 bits (679), Expect = 1.330e-84
Identity = 126/291 (43.30%), Postives = 191/291 (65.64%), Query Frame = 3 
Query:   93 VLDSEYFGIDKKRQLLLLKSVRWNYDIFTLDRITSGHPIVHLGMFLFEYHNLLTSFKIDYLKFLHTLTLLENNYHQKNPYHNALHAADVTQAMHCYVSDSKIRQKMKQFDFMVSLLGAMFHDVDHPGVNQAFLEKTNNYLSEFYKAQSVLENHHYRMALSILHETRVFHHFTTKQWGELQYRMYKLIMATDIARQNEYLDQFTNFIEQNIGIKEAFTKENKILIMQMALKCADICNPCREWRVAACWANLISAEFFRQGDRERRMNLPLAPTMDRYGITKPKVQTGFIRFL 965
            +LD +Y G   + + +L K   WN+DIF  DR+T+G+ +V L   LF  H L+  F +D +K    L +++ +YH +NPYHNA+HAADVTQAMHCY+ + K+   +  +D ++SL+ A  HD+DHPGVNQ FL KTN+YL+  YK  SVLENHH+R A+ +L E+ +F H   +   +++ ++  LI+ATDI+RQNEYL  F + +++     E     ++ L++QMALKCADICNPCR W ++  W+  ++ EFF QGD E++ +L ++P  DR+  +   +Q G   +L
Sbjct:  135 ILDDDYNG---QAKCMLEKVGNWNFDIFLFDRLTNGNSLVSLTFHLFSLHGLIEYFHLDMMKLRRFLVMIQEDYHSQNPYHNAVHAADVTQAMHCYLKEPKLANSVTPWDILLSLIAAATHDLDHPGVNQPFLIKTNHYLATLYKNTSVLENHHWRSAVGLLRESGLFSHLPLESRQQMETQIGALILATDISRQNEYLSLFRSHLDRGDLCLE--DTRHRHLVLQMALKCADICNPCRTWELSKQWSEKVTEEFFHQGDIEKKYHLGVSPLCDRHTESIANIQIGNYTYL 420
[Close]
BLAST of Phosphodiesterase vs. Ensembl Celegans
Match: pde-6 (Probable 3',5'-cyclic phosphodiesterase pde-6 [Source:UniProtKB/Swiss-Prot;Acc:Q9N2V9])

HSP 1 Score: 162.155 bits (409), Expect = 9.817e-45
Identity = 105/312 (33.65%), Postives = 158/312 (50.64%), Query Frame = 3 
Query:  159 WNYDIFTLDRITSGHPIVHLGMFLFEYHNLLTSFKIDYLKFLHTLTL-LENNYHQKNPYHNALHAADVTQAMHCYVSDSKIRQKMKQFDFMVSLLGAMFHDVDHPGVNQAFLEKTNNYLSEFYKAQSVLENHHYRMA--LSILHETRV--FHHFTTKQWGELQYRMYKLIMATDIARQNEYLDQFTNFIEQNIGIKEAFTKENKILIMQMALKCADICNPCREWRVAACWANLISAEFFRQGDRERRMNLPLA-PTMDRYGITKPKVQTGFIRFLVRPLFNKWNEFMKTRLSEKMVQQLEQNLLRWELKQNQ 1076
            W +DI  L++++  H +  +GM +FE   +           LH   L +E +YH  N YHNA HAADV QA   ++    +   + +   + +LL A  HD+DHPG   A+L  T   L+  Y   S+LENHH  +A  L++ H   V  F   + +++ ++++ M ++++ATDI+R  EYL +F         + E     N + I  M +KCADI NP REW +   WA+ I  E+F Q   E+   LP+     DR     P  Q GFI    R  F  + EF K  L E +  QLE N  +W++  +Q
Sbjct:  170 WKFDILHLEKVSDHHALSQVGMKVFERWKVCDVLGCSD-DLLHRWILSIEAHYHAGNTYHNATHAADVLQATSFFLDSPSVAVHVNESHAVAALLAAAVHDLDHPGRGNAYLINTRQSLAILYNDNSILENHHIALAFQLTLQHNANVNIFSSLSREEFIQMRHAMVEMVLATDISRHFEYLAKFNKM--HVTDVPEEQRDTNSLTICDMLVKCADISNPAREWGLCQRWAHRIVEEYFEQTREEKEKGLPVTMEVFDRNTCNVPITQCGFIDMFAREAFATFTEFAK--LGE-LSDQLESNYEKWKVMTSQ 475
[Close]
BLAST of Phosphodiesterase vs. Ensembl Celegans
Match: pde-4 (Probable 3',5'-cyclic phosphodiesterase pde-4 [Source:UniProtKB/Swiss-Prot;Acc:Q22000])

HSP 1 Score: 161.384 bits (407), Expect = 4.156e-44
Identity = 92/320 (28.75%), Postives = 164/320 (51.25%), Query Frame = 3 
Query:  159 WNYDIFTLDRITSGHPIVHLGMFLFEYHNLLTSFKIDYLKFLHTLTLLENNYHQKNPYHNALHAADVTQAMHCYVSDSKIRQKMKQFDFMVSLLGAMFHDVDHPGVNQAFLEKTNNYLSEFYKAQSVLENHHYRMALSILHETRVFHHFTTKQWGELQYR--MYKLIMATDIARQNEYLDQFTNFIE------QNIGIKEAFTKENKILIMQMALKCADICNPCREWRVAACWANLISAEFFRQGDRERRMNLPLAPTMDRYGITKPKVQTGFIRFLVRPLFNKWNEFMKTRLSEKMVQQLEQNLLRWELKQNQMAEKSD 1094
            W  D+F +D ++  H +  +   L    NL  +F+I     +  L  LE++Y + N YHN +HAADV Q+MH  +    + +     + + ++     HDVDHPG    +L  +NN L+  Y  +SVLE HH  +A  +L ++         +   LQ+R  +  +++ATD+++    L      +E       N+ + + +   +KI ++Q  +  AD+ NP +   +   W   I  E++RQGD+E+ + L ++P  DR  +T  K Q GFI ++V PL+  W + +    ++ ++ QLE+N    E  Q+++ E+ D
Sbjct:  225 WGPDVFKIDELSKNHSLTVVTFSLLRQRNLFKTFEIHQSTLVTYLLNLEHHY-RNNHYHNFIHAADVAQSMHVLLMSPVLTEVFTDLEVLAAIFAGAVHDVDHPGFTNQYLINSNNELAIMYNDESVLEQHHLAVAFKLLQDSNCDFLANLSRKQRLQFRKIVIDMVLATDMSKHMSLLADLKTMVEAKKVAGNNVIVLDKYN--DKIQVLQSMIHLADLSNPTKPIELYQQWNQRIMEEYWRQGDKEKELGLEISPMCDRGNVTIEKSQVGFIDYIVHPLYETWADLVYPD-AQNILDQLEEN---REWYQSRIPEEPD 537
[Close]
BLAST of Phosphodiesterase vs. Ensembl Celegans
Match: pde-4 (Probable 3',5'-cyclic phosphodiesterase pde-4 [Source:UniProtKB/Swiss-Prot;Acc:Q22000])

HSP 1 Score: 161.384 bits (407), Expect = 8.183e-44
Identity = 94/322 (29.19%), Postives = 167/322 (51.86%), Query Frame = 3 
Query:  159 WNYDIFTLDRITSGHPIVHLGMFLFEYHNLLTSFKIDYLKFLHTLTLLENNYHQKNPYHNALHAADVTQAMHCYVSDSKIRQKMKQFDFMVSLLGAMFHDVDHPGVNQAFLEKTNNYLSEFYKAQSVLENHHYRMALSILHETRV--FHHFTTKQWGELQYR--MYKLIMATDIARQNEYLDQFTNFIE------QNIGIKEAFTKENKILIMQMALKCADICNPCREWRVAACWANLISAEFFRQGDRERRMNLPLAPTMDRYGITKPKVQTGFIRFLVRPLFNKWNEFMKTRLSEKMVQQLEQNLLRWELKQNQMAEKSD 1094
            W  D+F +D ++  H +  +   L    NL  +F+I     +  L  LE++Y + N YHN +HAADV Q+MH  +    + +     + + ++     HDVDHPG    +L  +NN L+  Y  +SVLE HH  +A  +L ++      + + KQ   LQ+R  +  +++ATD+++    L      +E       N+ + + +   +KI ++Q  +  AD+ NP +   +   W   I  E++RQGD+E+ + L ++P  DR  +T  K Q GFI ++V PL+  W + +    ++ ++ QLE+N    E  Q+++ E+ D
Sbjct:  275 WGPDVFKIDELSKNHSLTVVTFSLLRQRNLFKTFEIHQSTLVTYLLNLEHHY-RNNHYHNFIHAADVAQSMHVLLMSPVLTEVFTDLEVLAAIFAGAVHDVDHPGFTNQYLINSNNELAIMYNDESVLEQHHLAVAFKLLQDSNCDFLANLSRKQ--RLQFRKIVIDMVLATDMSKHMSLLADLKTMVEAKKVAGNNVIVLDKYN--DKIQVLQSMIHLADLSNPTKPIELYQQWNQRIMEEYWRQGDKEKELGLEISPMCDRGNVTIEKSQVGFIDYIVHPLYETWADLVYPD-AQNILDQLEEN---REWYQSRIPEEPD 587
[Close]
BLAST of Phosphodiesterase vs. Ensembl Celegans
Match: pde-4 (Probable 3',5'-cyclic phosphodiesterase pde-4 [Source:UniProtKB/Swiss-Prot;Acc:Q22000])

HSP 1 Score: 161.384 bits (407), Expect = 1.157e-43
Identity = 94/322 (29.19%), Postives = 167/322 (51.86%), Query Frame = 3 
Query:  159 WNYDIFTLDRITSGHPIVHLGMFLFEYHNLLTSFKIDYLKFLHTLTLLENNYHQKNPYHNALHAADVTQAMHCYVSDSKIRQKMKQFDFMVSLLGAMFHDVDHPGVNQAFLEKTNNYLSEFYKAQSVLENHHYRMALSILHETRV--FHHFTTKQWGELQYR--MYKLIMATDIARQNEYLDQFTNFIE------QNIGIKEAFTKENKILIMQMALKCADICNPCREWRVAACWANLISAEFFRQGDRERRMNLPLAPTMDRYGITKPKVQTGFIRFLVRPLFNKWNEFMKTRLSEKMVQQLEQNLLRWELKQNQMAEKSD 1094
            W  D+F +D ++  H +  +   L    NL  +F+I     +  L  LE++Y + N YHN +HAADV Q+MH  +    + +     + + ++     HDVDHPG    +L  +NN L+  Y  +SVLE HH  +A  +L ++      + + KQ   LQ+R  +  +++ATD+++    L      +E       N+ + + +   +KI ++Q  +  AD+ NP +   +   W   I  E++RQGD+E+ + L ++P  DR  +T  K Q GFI ++V PL+  W + +    ++ ++ QLE+N    E  Q+++ E+ D
Sbjct:  288 WGPDVFKIDELSKNHSLTVVTFSLLRQRNLFKTFEIHQSTLVTYLLNLEHHY-RNNHYHNFIHAADVAQSMHVLLMSPVLTEVFTDLEVLAAIFAGAVHDVDHPGFTNQYLINSNNELAIMYNDESVLEQHHLAVAFKLLQDSNCDFLANLSRKQ--RLQFRKIVIDMVLATDMSKHMSLLADLKTMVEAKKVAGNNVIVLDKYN--DKIQVLQSMIHLADLSNPTKPIELYQQWNQRIMEEYWRQGDKEKELGLEISPMCDRGNVTIEKSQVGFIDYIVHPLYETWADLVYPD-AQNILDQLEEN---REWYQSRIPEEPD 600
[Close]
BLAST of Phosphodiesterase vs. Ensembl Celegans
Match: pde-4 (Probable 3',5'-cyclic phosphodiesterase pde-4 [Source:UniProtKB/Swiss-Prot;Acc:Q22000])

HSP 1 Score: 161.384 bits (407), Expect = 1.329e-43
Identity = 94/322 (29.19%), Postives = 167/322 (51.86%), Query Frame = 3 
Query:  159 WNYDIFTLDRITSGHPIVHLGMFLFEYHNLLTSFKIDYLKFLHTLTLLENNYHQKNPYHNALHAADVTQAMHCYVSDSKIRQKMKQFDFMVSLLGAMFHDVDHPGVNQAFLEKTNNYLSEFYKAQSVLENHHYRMALSILHETRV--FHHFTTKQWGELQYR--MYKLIMATDIARQNEYLDQFTNFIE------QNIGIKEAFTKENKILIMQMALKCADICNPCREWRVAACWANLISAEFFRQGDRERRMNLPLAPTMDRYGITKPKVQTGFIRFLVRPLFNKWNEFMKTRLSEKMVQQLEQNLLRWELKQNQMAEKSD 1094
            W  D+F +D ++  H +  +   L    NL  +F+I     +  L  LE++Y + N YHN +HAADV Q+MH  +    + +     + + ++     HDVDHPG    +L  +NN L+  Y  +SVLE HH  +A  +L ++      + + KQ   LQ+R  +  +++ATD+++    L      +E       N+ + + +   +KI ++Q  +  AD+ NP +   +   W   I  E++RQGD+E+ + L ++P  DR  +T  K Q GFI ++V PL+  W + +    ++ ++ QLE+N    E  Q+++ E+ D
Sbjct:  300 WGPDVFKIDELSKNHSLTVVTFSLLRQRNLFKTFEIHQSTLVTYLLNLEHHY-RNNHYHNFIHAADVAQSMHVLLMSPVLTEVFTDLEVLAAIFAGAVHDVDHPGFTNQYLINSNNELAIMYNDESVLEQHHLAVAFKLLQDSNCDFLANLSRKQ--RLQFRKIVIDMVLATDMSKHMSLLADLKTMVEAKKVAGNNVIVLDKYN--DKIQVLQSMIHLADLSNPTKPIELYQQWNQRIMEEYWRQGDKEKELGLEISPMCDRGNVTIEKSQVGFIDYIVHPLYETWADLVYPD-AQNILDQLEEN---REWYQSRIPEEPD 612
[Close]
BLAST of Phosphodiesterase vs. Ensembl Fly
Match: dnc (gene:FBgn0000479 transcript:FBtr0070522)

HSP 1 Score: 173.711 bits (439), Expect = 1.251e-48
Identity = 95/322 (29.50%), Postives = 167/322 (51.86%), Query Frame = 3 
Query:  111 FGIDKKRQ----LLLLKSVRWNYDIFTLDRITSGHPIVHLGMFLFEYHNLLTSFKIDYLKFLHTLTLLENNYHQKNPYHNALHAADVTQAMHCYVSDSKIRQKMKQFDFMVSLLGAMFHDVDHPGVNQAFLEKTNNYLSEFYKAQSVLENHHYRMALSILHE--TRVFHHFTTKQWGELQYRMYKLIMATDIARQNEYLDQFTNFIE----QNIGIKEAFTKENKILIMQMALKCADICNPCREWRVAACWANLISAEFFRQGDRERRMNLPLAPTMDRYGITKPKVQTGFIRFLVRPLFNKWNEFMKTRLSEKMVQQLEQN 1046
            FG++  R+     LL +   W   IF++   +   P+  +   +F+   LLTS  I    FL+ ++ LE++Y + NP+HN+LHAADVTQ+ +  ++   +       +   +L  A  HDVDHPG+   FL  +++ L+  Y  +SVLENHH  +A  +L      +F +   KQ   L+  +  ++++TD+++    L      +E       G+       ++I +++  + CAD+ NP +   +   W  L+  EFF QGD+ER   + ++P  DR+  T  K Q GFI ++V PL+  W + +    ++ ++  LE+N
Sbjct:  105 FGVETPRENELGTLLGELDTWGIQIFSIGEFSVNRPLTCVAYTIFQSRELLTSLMIPPKTFLNFMSTLEDHYVKDNPFHNSLHAADVTQSTNVLLNTPALEGVFTPLEVGGALFAACIHDVDHPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQNQGCDIFCNMQKKQRQTLRKMVIDIVLSTDMSKHMSLLADLKTMVETKKVAGSGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFLQGDKERESGMDISPMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPD-AQDILDTLEEN 425
[Close]
BLAST of Phosphodiesterase vs. Ensembl Fly
Match: dnc (gene:FBgn0000479 transcript:FBtr0070518)

HSP 1 Score: 173.326 bits (438), Expect = 1.006e-47
Identity = 95/322 (29.50%), Postives = 167/322 (51.86%), Query Frame = 3 
Query:  111 FGIDKKRQ----LLLLKSVRWNYDIFTLDRITSGHPIVHLGMFLFEYHNLLTSFKIDYLKFLHTLTLLENNYHQKNPYHNALHAADVTQAMHCYVSDSKIRQKMKQFDFMVSLLGAMFHDVDHPGVNQAFLEKTNNYLSEFYKAQSVLENHHYRMALSILHE--TRVFHHFTTKQWGELQYRMYKLIMATDIARQNEYLDQFTNFIE----QNIGIKEAFTKENKILIMQMALKCADICNPCREWRVAACWANLISAEFFRQGDRERRMNLPLAPTMDRYGITKPKVQTGFIRFLVRPLFNKWNEFMKTRLSEKMVQQLEQN 1046
            FG++  R+     LL +   W   IF++   +   P+  +   +F+   LLTS  I    FL+ ++ LE++Y + NP+HN+LHAADVTQ+ +  ++   +       +   +L  A  HDVDHPG+   FL  +++ L+  Y  +SVLENHH  +A  +L      +F +   KQ   L+  +  ++++TD+++    L      +E       G+       ++I +++  + CAD+ NP +   +   W  L+  EFF QGD+ER   + ++P  DR+  T  K Q GFI ++V PL+  W + +    ++ ++  LE+N
Sbjct:  226 FGVETPRENELGTLLGELDTWGIQIFSIGEFSVNRPLTCVAYTIFQSRELLTSLMIPPKTFLNFMSTLEDHYVKDNPFHNSLHAADVTQSTNVLLNTPALEGVFTPLEVGGALFAACIHDVDHPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQNQGCDIFCNMQKKQRQTLRKMVIDIVLSTDMSKHMSLLADLKTMVETKKVAGSGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFLQGDKERESGMDISPMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPD-AQDILDTLEEN 546
[Close]
BLAST of Phosphodiesterase vs. Ensembl Fly
Match: dnc (gene:FBgn0000479 transcript:FBtr0333312)

HSP 1 Score: 173.326 bits (438), Expect = 1.006e-47
Identity = 95/322 (29.50%), Postives = 167/322 (51.86%), Query Frame = 3 
Query:  111 FGIDKKRQ----LLLLKSVRWNYDIFTLDRITSGHPIVHLGMFLFEYHNLLTSFKIDYLKFLHTLTLLENNYHQKNPYHNALHAADVTQAMHCYVSDSKIRQKMKQFDFMVSLLGAMFHDVDHPGVNQAFLEKTNNYLSEFYKAQSVLENHHYRMALSILHE--TRVFHHFTTKQWGELQYRMYKLIMATDIARQNEYLDQFTNFIE----QNIGIKEAFTKENKILIMQMALKCADICNPCREWRVAACWANLISAEFFRQGDRERRMNLPLAPTMDRYGITKPKVQTGFIRFLVRPLFNKWNEFMKTRLSEKMVQQLEQN 1046
            FG++  R+     LL +   W   IF++   +   P+  +   +F+   LLTS  I    FL+ ++ LE++Y + NP+HN+LHAADVTQ+ +  ++   +       +   +L  A  HDVDHPG+   FL  +++ L+  Y  +SVLENHH  +A  +L      +F +   KQ   L+  +  ++++TD+++    L      +E       G+       ++I +++  + CAD+ NP +   +   W  L+  EFF QGD+ER   + ++P  DR+  T  K Q GFI ++V PL+  W + +    ++ ++  LE+N
Sbjct:  226 FGVETPRENELGTLLGELDTWGIQIFSIGEFSVNRPLTCVAYTIFQSRELLTSLMIPPKTFLNFMSTLEDHYVKDNPFHNSLHAADVTQSTNVLLNTPALEGVFTPLEVGGALFAACIHDVDHPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQNQGCDIFCNMQKKQRQTLRKMVIDIVLSTDMSKHMSLLADLKTMVETKKVAGSGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFLQGDKERESGMDISPMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPD-AQDILDTLEEN 546
[Close]
BLAST of Phosphodiesterase vs. Ensembl Fly
Match: dnc (gene:FBgn0000479 transcript:FBtr0070521)

HSP 1 Score: 173.326 bits (438), Expect = 1.008e-47
Identity = 95/322 (29.50%), Postives = 167/322 (51.86%), Query Frame = 3 
Query:  111 FGIDKKRQ----LLLLKSVRWNYDIFTLDRITSGHPIVHLGMFLFEYHNLLTSFKIDYLKFLHTLTLLENNYHQKNPYHNALHAADVTQAMHCYVSDSKIRQKMKQFDFMVSLLGAMFHDVDHPGVNQAFLEKTNNYLSEFYKAQSVLENHHYRMALSILHE--TRVFHHFTTKQWGELQYRMYKLIMATDIARQNEYLDQFTNFIE----QNIGIKEAFTKENKILIMQMALKCADICNPCREWRVAACWANLISAEFFRQGDRERRMNLPLAPTMDRYGITKPKVQTGFIRFLVRPLFNKWNEFMKTRLSEKMVQQLEQN 1046
            FG++  R+     LL +   W   IF++   +   P+  +   +F+   LLTS  I    FL+ ++ LE++Y + NP+HN+LHAADVTQ+ +  ++   +       +   +L  A  HDVDHPG+   FL  +++ L+  Y  +SVLENHH  +A  +L      +F +   KQ   L+  +  ++++TD+++    L      +E       G+       ++I +++  + CAD+ NP +   +   W  L+  EFF QGD+ER   + ++P  DR+  T  K Q GFI ++V PL+  W + +    ++ ++  LE+N
Sbjct:  246 FGVETPRENELGTLLGELDTWGIQIFSIGEFSVNRPLTCVAYTIFQSRELLTSLMIPPKTFLNFMSTLEDHYVKDNPFHNSLHAADVTQSTNVLLNTPALEGVFTPLEVGGALFAACIHDVDHPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQNQGCDIFCNMQKKQRQTLRKMVIDIVLSTDMSKHMSLLADLKTMVETKKVAGSGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFLQGDKERESGMDISPMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPD-AQDILDTLEEN 566
[Close]
BLAST of Phosphodiesterase vs. Ensembl Fly
Match: Pde8 (gene:FBgn0266377 transcript:FBtr0344176)

HSP 1 Score: 167.548 bits (423), Expect = 2.153e-47
Identity = 101/328 (30.79%), Postives = 175/328 (53.35%), Query Frame = 3 
Query:  138 LLLKSVRWNYDIFTLDRITSGHPIVHLGMFLFEYHNLLTSFKIDYLKFLHTLTLLENNYHQKNPYHNALHAADVTQAMHCYVSD--SKIRQKMKQFDFMVSLLGAMFHDVDHPGVNQAFLEKTNNYLSEFYKAQSVLENHHYRMALSIL---HETRVFHHFTTKQWGELQYRMYKLIMATDIARQNEYLDQFTNFI--EQNIGIKEAFTKENKILIMQMALKCADICNPCREWRVAACWANLISAEFFRQGDRERRMNLPLA-PTMDRYGITKPKVQTGFIRFLVRPLFNKWNEFMKTRLSEKMVQQLEQNLLRW----ELKQNQMAE 1085
            LL +S+ W++DIF L+ IT  HP+++LGM +F   ++  +  ID       L ++E +Y + N YHN+ HAADV QA   +++   +K    M + +   +L+ A  HDVDHPG + AFL  +N+ L+  Y   +VLENHH  +   +     +  +F +   + +   +  +  +I+AT++ R  E+L +F +    E+         +E  IL+ +M +K AD+ NP R  +    WA  I+ E+F Q D E++ +LP+  P  DR   + PK Q GFI ++++ + + W  F+      +++  ++ N  +W    E   N +AE
Sbjct:   61 LLDESLSWDFDIFKLEEITDYHPLLYLGMEMFRRFDVFATLNIDENVCKAWLAVIEAHYRKSNTYHNSTHAADVMQATGAFITQLTNKDMLVMDRMEEATALIAAAAHDVDHPGRSSAFLCNSNDALAVLYNDLTVLENHHAAITFKLTLGDDKINIFKNLDKETYKSARSTIIDMILATEMTRHFEHLAKFVSVFGGEEPRDHNPQTDEETSILMRRMLIKVADVSNPARPMQFCIEWARRIAEEYFMQTDEEKQRHLPIVMPMFDRATCSIPKSQIGFIEYIIQDMMHAWESFIDM---PQLITYMQINYSQWKKYDEQGVNTLAE 385
[Close]
BLAST of Phosphodiesterase vs. Ensembl Zebrafish
Match: pde7a (phosphodiesterase 7A [Source:ZFIN;Acc:ZDB-GENE-031222-10])

HSP 1 Score: 304.679 bits (779), Expect = 6.284e-99
Identity = 149/353 (42.21%), Postives = 220/353 (62.32%), Query Frame = 3 
Query:   93 VLDSEYFGIDKKRQLLLLKSVRWNYDIFTLDRITSGHPIVHLGMFLFEYHNLLTSFKIDYLKFLHTLTLLENNYHQKNPYHNALHAADVTQAMHCYVSDSKIRQKMKQFDFMVSLLGAMFHDVDHPGVNQAFLEKTNNYLSEFYKAQSVLENHHYRMALSILHETRVFHHFTTKQWGELQYRMYKLIMATDIARQNEYLDQF-TNFIEQNIGIKEAFTKENKILIMQMALKCADICNPCREWRVAACWANLISAEFFRQGDRERRMNLPLAPTMDRYGITKPKVQTGFIRFLVRPLFNKWNEFMKTRLSEKMVQQLEQNLLRWELKQNQMAEKSDMLGEDAKPVSQTIPKTTA 1148
            +LD +Y G   + + +L K   WN+DIF  DR+T+G+ +V L   L   + L+  F++D +K    L L++ +YH +NPYHNA+HAADVTQAMHCY+ + K+ Q +  FD ++ LL A  HD+DHPGVNQ FL KTN+YL+  Y+  SVLENHH+R A+ +L ET +F H   +    ++ ++  LI+ATDI+RQNEYL +F T+  E ++ +  A    ++  ++QMALKCADICNPCR W ++  W+  ++ EFF QGD E+++ L ++P  D    T   VQ GF+ ++V PLF +W  F  TRLS+ M+  L  N   W   + + +  S+  GE     S   P + A
Sbjct:  137 ILDEDYCG---QAKCMLEKVGSWNFDIFLFDRLTNGNSLVFLTFHLLSQYGLIELFQLDMVKVRRFLVLVQEDYHNQNPYHNAVHAADVTQAMHCYLREPKLAQSLTSFDILLGLLAAATHDLDHPGVNQPFLIKTNHYLAALYRNTSVLENHHWRSAVGLLRETELFSHLPAEDSLSIERQLGSLILATDISRQNEYLSRFRTHLDENDLNLGNA---SHRHFVLQMALKCADICNPCRPWELSKQWSEKVTEEFFHQGDIEKKLKLEISPLCDSEANTIASVQIGFMTYVVEPLFAEWARFSDTRLSQTMLGHLGLNKASWSTMEPEASGSSED-GESDPARSSEEPSSRA 482
[Close]
BLAST of Phosphodiesterase vs. Ensembl Zebrafish
Match: pde4ca (phosphodiesterase 4C, cAMP-specific a [Source:ZFIN;Acc:ZDB-GENE-070912-373])

HSP 1 Score: 193.741 bits (491), Expect = 9.153e-55
Identity = 104/341 (30.50%), Postives = 171/341 (50.15%), Query Frame = 3 
Query:   54 AGCKPPRRIDIYGVLDSEYFGIDKKRQLLLLKSV----RWNYDIFTLDRITSGHPIVHLGMFLFEYHNLLTSFKIDYLKFLHTLTLLENNYHQKNPYHNALHAADVTQAMHCYVSDSKIRQKMKQFDFMVSLLGAMFHDVDHPGVNQAFLEKTNNYLSEFYKAQSVLENHHYRMALSILHETR--VFHHFTTKQWGELQYRMYKLIMATDIARQNEYLDQFTNFIE----QNIGIKEAFTKENKILIMQMALKCADICNPCREWRVAACWANLISAEFFRQGDRERRMNLPLAPTMDRYGITKPKVQTGFIRFLVRPLFNKWNEFMKTRLSEKMVQQLEQN 1046
            +G K P             FG+   R+ LL K +    RW  D+F +   +   P+       F+  +LL SFKI    F++ +T LE NY     YHN++HAADV Q+ H  +S   +       + + ++  +  HDVDHPGV+  FL  TN+ L+  Y   SVLENHH  +   +L E    +F + T KQ   L+  +  +++ATD+++    L      +E     ++G+       ++I ++Q  + CAD+ NP +   +   W + I  EFF QGDRER   + ++P  D++  +  K Q GFI ++V PL+  W + +    +++++  LE N
Sbjct:  252 SGVKKPTHSSNIAPSSIPRFGVSTNREDLLAKELEDFDRWGVDMFKISECSGNRPLTVAMYTTFQERDLLKSFKIPVDTFINYMTALEENYRSDVAYHNSIHAADVVQSTHVLLSTPALEAVFTDLEILAAMFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDMVLATDMSKHMNLLADLKTMVETKKVTSLGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLELYRQWTDRIMVEFFTQGDRERDKGMEISPMCDKHNASIEKSQVGFIDYIVHPLWETWADLVHPD-AQEILDTLEDN 591
[Close]
BLAST of Phosphodiesterase vs. Ensembl Zebrafish
Match: pde4ca (phosphodiesterase 4C, cAMP-specific a [Source:ZFIN;Acc:ZDB-GENE-070912-373])

HSP 1 Score: 193.741 bits (491), Expect = 9.153e-55
Identity = 104/341 (30.50%), Postives = 171/341 (50.15%), Query Frame = 3 
Query:   54 AGCKPPRRIDIYGVLDSEYFGIDKKRQLLLLKSV----RWNYDIFTLDRITSGHPIVHLGMFLFEYHNLLTSFKIDYLKFLHTLTLLENNYHQKNPYHNALHAADVTQAMHCYVSDSKIRQKMKQFDFMVSLLGAMFHDVDHPGVNQAFLEKTNNYLSEFYKAQSVLENHHYRMALSILHETR--VFHHFTTKQWGELQYRMYKLIMATDIARQNEYLDQFTNFIE----QNIGIKEAFTKENKILIMQMALKCADICNPCREWRVAACWANLISAEFFRQGDRERRMNLPLAPTMDRYGITKPKVQTGFIRFLVRPLFNKWNEFMKTRLSEKMVQQLEQN 1046
            +G K P             FG+   R+ LL K +    RW  D+F +   +   P+       F+  +LL SFKI    F++ +T LE NY     YHN++HAADV Q+ H  +S   +       + + ++  +  HDVDHPGV+  FL  TN+ L+  Y   SVLENHH  +   +L E    +F + T KQ   L+  +  +++ATD+++    L      +E     ++G+       ++I ++Q  + CAD+ NP +   +   W + I  EFF QGDRER   + ++P  D++  +  K Q GFI ++V PL+  W + +    +++++  LE N
Sbjct:  252 SGVKKPTHSSNIAPSSIPRFGVSTNREDLLAKELEDFDRWGVDMFKISECSGNRPLTVAMYTTFQERDLLKSFKIPVDTFINYMTALEENYRSDVAYHNSIHAADVVQSTHVLLSTPALEAVFTDLEILAAMFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDMVLATDMSKHMNLLADLKTMVETKKVTSLGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLELYRQWTDRIMVEFFTQGDRERDKGMEISPMCDKHNASIEKSQVGFIDYIVHPLWETWADLVHPD-AQEILDTLEDN 591
[Close]
BLAST of Phosphodiesterase vs. Ensembl Zebrafish
Match: pde4ca (phosphodiesterase 4C, cAMP-specific a [Source:ZFIN;Acc:ZDB-GENE-070912-373])

HSP 1 Score: 193.356 bits (490), Expect = 1.690e-54
Identity = 105/341 (30.79%), Postives = 169/341 (49.56%), Query Frame = 3 
Query:   54 AGCKPPRRIDIYGVLDSEYFGIDKKRQLLLLKSV----RWNYDIFTLDRITSGHPIVHLGMFLFEYHNLLTSFKIDYLKFLHTLTLLENNYHQKNPYHNALHAADVTQAMHCYVSDSKIRQKMKQFDFMVSLLGAMFHDVDHPGVNQAFLEKTNNYLSEFYKAQSVLENHHYRMALSILHETR--VFHHFTTKQWGELQYRMYKLIMATDIARQNEYLDQFTNFIE----QNIGIKEAFTKENKILIMQMALKCADICNPCREWRVAACWANLISAEFFRQGDRERRMNLPLAPTMDRYGITKPKVQTGFIRFLVRPLFNKWNEFMKTRLSEKMVQQLEQN 1046
            +G K P             FG+   R+ LL K +    RW  D+F +   +   P+       F+  +LL SFKI    F++ +T LE NY     YHN++HAADV Q+ H  +S   +       + + ++  +  HDVDHPGV+  FL  TN+ L+  Y   SVLENHH  +   +L E    +F + T KQ   L+  +  +++ATD+++    L      +E     ++G+       ++I ++Q  + CAD+ NP +   +   W + I  EFF QGDRER   + ++P  D++  +  K Q GFI ++V PL+  W + +     E ++  LE N
Sbjct:  258 SGVKKPTHSSNIAPSSIPRFGVSTNREDLLAKELEDFDRWGVDMFKISECSGNRPLTVAMYTTFQERDLLKSFKIPVDTFINYMTALEENYRSDVAYHNSIHAADVVQSTHVLLSTPALEAVFTDLEILAAMFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDMVLATDMSKHMNLLADLKTMVETKKVTSLGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLELYRQWTDRIMVEFFTQGDRERDKGMEISPMCDKHNASIEKSQVGFIDYIVHPLWETWADLVHPDAQE-ILDTLEDN 597
[Close]
BLAST of Phosphodiesterase vs. Ensembl Zebrafish
Match: pde4ba (phosphodiesterase 4B, cAMP-specific a [Source:ZFIN;Acc:ZDB-GENE-030131-9570])

HSP 1 Score: 182.956 bits (463), Expect = 1.639e-52
Identity = 101/322 (31.37%), Postives = 171/322 (53.11%), Query Frame = 3 
Query:  111 FGIDKKRQLLLLKSV----RWNYDIFTLDRITSGHPIVHLGMFLFEYHNLLTSFKIDYLKFLHTLTLLENNYHQKNPYHNALHAADVTQAMHCYVSDSKIRQKMKQFDFMVSLLGAMFHDVDHPGVNQAFLEKTNNYLSEFYKAQSVLENHHYRMALSILHETR--VFHHFTTKQWGELQYRMYKLIMATDIARQNEYLDQFTNFIE----QNIGIKEAFTKENKILIMQMALKCADICNPCREWRVAACWANLISAEFFRQGDRERRMNLPLAPTMDRYGITKPKVQTGFIRFLVRPLFNKWNEFMKTRLSEKMVQQLEQN 1046
            FG+   ++ LL K +    RW  +IFT+   ++  P+  +   +F+  +LL +FKI    F+  +  LE++YHQ   YHN+LHAADV Q+ H  +S   +       + + ++  A  HDVDHPGV+  FL  TN+ L+  Y  +SVLENHH  +   +L E    +F + T KQ   L+  +  +++ATD+++    L      +E     + G+       ++I +++  + CAD+ NP +   +   W + I  EFF QGDRER   + ++P  D++  +  K Q GFI ++V PL+  W + +    ++ ++  LE N
Sbjct:   94 FGVKTDKEDLLSKELEDLNRWGLNIFTVSEYSNNRPLTCIMYAIFQERDLLKTFKIPTDTFVTYMMTLEDHYHQDVAYHNSLHAADVAQSTHILLSTPALDAVFTDLEILAAIFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLENHHLAVGFKLLQEDNCDIFQNLTKKQRTSLRRMVIDMVLATDMSKHMSLLADLKTMVETKKVTSSGVLLLDNYTDRIQVLRNMVHCADLSNPTKSLELYRQWTDRIMEEFFHQGDRERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVHPD-AQDILDTLEDN 414
[Close]
BLAST of Phosphodiesterase vs. Ensembl Xenopus
Match: PDE7A (phosphodiesterase 7A [Source:NCBI gene;Acc:100498541])

HSP 1 Score: 298.13 bits (762), Expect = 5.696e-97
Identity = 141/337 (41.84%), Postives = 221/337 (65.58%), Query Frame = 3 
Query:   93 VLDSEYFGIDKKRQLLLLKSVRWNYDIFTLDRITSGHPIVHLGMFLFEYHNLLTSFKIDYLKFLHTLTLLENNYHQKNPYHNALHAADVTQAMHCYVSDSKIRQKMKQFDFMVSLLGAMFHDVDHPGVNQAFLEKTNNYLSEFYKAQSVLENHHYRMALSILHETRVFHHFTTKQWGELQYRMYKLIMATDIARQNEYLDQFTNFIEQ-NIGIKEAFTKENKILIMQMALKCADICNPCREWRVAACWANLISAEFFRQGDRERRMNLPLAPTMDRYGITKPKVQTGFIRFLVRPLFNKWNEFMKTRLSEKMVQQLEQNLLRWE--LKQNQMAEKSD 1094
            +LD +Y G   + + +L K   W++DIF  DR+T+G+ +V L   L  +H L+  F++D +K    L +++ +YH +NPYHNA+HAADVTQAM+C++ + K+ +    +D ++ L+ A  HD+DHPGVNQ+FL KTN+YL+  YK  SVLENHH+R A+ +L E+ +F H T ++   ++ ++  +I+ATDI+RQNEYL QF   +++ ++ +  A    +++ I+QMALKCADICNPCR W ++  W+  ++ EFF QGD ER+  L ++P  DR       +Q GFI +LV PLF +W  F  TRLS+ M+  +  N   W+  L++   +E++D
Sbjct:  102 ILDDDYNG---QAKCMLEKVGSWSFDIFLFDRLTNGNSLVTLTFHLLSHHGLIDHFQLDMVKLRRFLVMVQEDYHSQNPYHNAVHAADVTQAMYCFLKEPKLAKSFTPWDILLGLIAAATHDLDHPGVNQSFLIKTNHYLATLYKNTSVLENHHWRSAVGLLRESGLFAHMTLEERQHMEGQLGSIILATDISRQNEYLSQFRTHLDRGDLCLDNA---SDRLFILQMALKCADICNPCRTWELSKQWSEKVTEEFFYQGDVERKYKLDVSPLCDRQTSNIANIQIGFITYLVEPLFVEWARFSNTRLSQTMLGHVGLNKASWKGMLQERSSSEEAD 432
[Close]
BLAST of Phosphodiesterase vs. Ensembl Xenopus
Match: PDE7A (phosphodiesterase 7A [Source:NCBI gene;Acc:100498541])

HSP 1 Score: 297.745 bits (761), Expect = 7.180e-97
Identity = 141/337 (41.84%), Postives = 221/337 (65.58%), Query Frame = 3 
Query:   93 VLDSEYFGIDKKRQLLLLKSVRWNYDIFTLDRITSGHPIVHLGMFLFEYHNLLTSFKIDYLKFLHTLTLLENNYHQKNPYHNALHAADVTQAMHCYVSDSKIRQKMKQFDFMVSLLGAMFHDVDHPGVNQAFLEKTNNYLSEFYKAQSVLENHHYRMALSILHETRVFHHFTTKQWGELQYRMYKLIMATDIARQNEYLDQFTNFIEQ-NIGIKEAFTKENKILIMQMALKCADICNPCREWRVAACWANLISAEFFRQGDRERRMNLPLAPTMDRYGITKPKVQTGFIRFLVRPLFNKWNEFMKTRLSEKMVQQLEQNLLRWE--LKQNQMAEKSD 1094
            +LD +Y G   + + +L K   W++DIF  DR+T+G+ +V L   L  +H L+  F++D +K    L +++ +YH +NPYHNA+HAADVTQAM+C++ + K+ +    +D ++ L+ A  HD+DHPGVNQ+FL KTN+YL+  YK  SVLENHH+R A+ +L E+ +F H T ++   ++ ++  +I+ATDI+RQNEYL QF   +++ ++ +  A    +++ I+QMALKCADICNPCR W ++  W+  ++ EFF QGD ER+  L ++P  DR       +Q GFI +LV PLF +W  F  TRLS+ M+  +  N   W+  L++   +E++D
Sbjct:  100 ILDDDYNG---QAKCMLEKVGSWSFDIFLFDRLTNGNSLVTLTFHLLSHHGLIDHFQLDMVKLRRFLVMVQEDYHSQNPYHNAVHAADVTQAMYCFLKEPKLAKSFTPWDILLGLIAAATHDLDHPGVNQSFLIKTNHYLATLYKNTSVLENHHWRSAVGLLRESGLFAHMTLEERQHMEGQLGSIILATDISRQNEYLSQFRTHLDRGDLCLDNA---SDRLFILQMALKCADICNPCRTWELSKQWSEKVTEEFFYQGDVERKYKLDVSPLCDRQTSNIANIQIGFITYLVEPLFVEWARFSNTRLSQTMLGHVGLNKASWKGMLQERSSSEEAD 430
[Close]
BLAST of Phosphodiesterase vs. Ensembl Xenopus
Match: PDE7A (phosphodiesterase 7A [Source:NCBI gene;Acc:100498541])

HSP 1 Score: 297.745 bits (761), Expect = 1.816e-96
Identity = 141/337 (41.84%), Postives = 221/337 (65.58%), Query Frame = 3 
Query:   93 VLDSEYFGIDKKRQLLLLKSVRWNYDIFTLDRITSGHPIVHLGMFLFEYHNLLTSFKIDYLKFLHTLTLLENNYHQKNPYHNALHAADVTQAMHCYVSDSKIRQKMKQFDFMVSLLGAMFHDVDHPGVNQAFLEKTNNYLSEFYKAQSVLENHHYRMALSILHETRVFHHFTTKQWGELQYRMYKLIMATDIARQNEYLDQFTNFIEQ-NIGIKEAFTKENKILIMQMALKCADICNPCREWRVAACWANLISAEFFRQGDRERRMNLPLAPTMDRYGITKPKVQTGFIRFLVRPLFNKWNEFMKTRLSEKMVQQLEQNLLRWE--LKQNQMAEKSD 1094
            +LD +Y G   + + +L K   W++DIF  DR+T+G+ +V L   L  +H L+  F++D +K    L +++ +YH +NPYHNA+HAADVTQAM+C++ + K+ +    +D ++ L+ A  HD+DHPGVNQ+FL KTN+YL+  YK  SVLENHH+R A+ +L E+ +F H T ++   ++ ++  +I+ATDI+RQNEYL QF   +++ ++ +  A    +++ I+QMALKCADICNPCR W ++  W+  ++ EFF QGD ER+  L ++P  DR       +Q GFI +LV PLF +W  F  TRLS+ M+  +  N   W+  L++   +E++D
Sbjct:  135 ILDDDYNG---QAKCMLEKVGSWSFDIFLFDRLTNGNSLVTLTFHLLSHHGLIDHFQLDMVKLRRFLVMVQEDYHSQNPYHNAVHAADVTQAMYCFLKEPKLAKSFTPWDILLGLIAAATHDLDHPGVNQSFLIKTNHYLATLYKNTSVLENHHWRSAVGLLRESGLFAHMTLEERQHMEGQLGSIILATDISRQNEYLSQFRTHLDRGDLCLDNA---SDRLFILQMALKCADICNPCRTWELSKQWSEKVTEEFFYQGDVERKYKLDVSPLCDRQTSNIANIQIGFITYLVEPLFVEWARFSNTRLSQTMLGHVGLNKASWKGMLQERSSSEEAD 465
[Close]
BLAST of Phosphodiesterase vs. Ensembl Xenopus
Match: PDE7A (phosphodiesterase 7A [Source:NCBI gene;Acc:100498541])

HSP 1 Score: 293.123 bits (749), Expect = 2.327e-96
Identity = 138/322 (42.86%), Postives = 212/322 (65.84%), Query Frame = 3 
Query:  138 LLLKSVRWNYDIFTLDRITSGHPIVHLGMFLFEYHNLLTSFKIDYLKFLHTLTLLENNYHQKNPYHNALHAADVTQAMHCYVSDSKIRQKMKQFDFMVSLLGAMFHDVDHPGVNQAFLEKTNNYLSEFYKAQSVLENHHYRMALSILHETRVFHHFTTKQWGELQYRMYKLIMATDIARQNEYLDQF-TNFIEQNIGIKEAFTKENKILIMQMALKCADICNPCREWRVAACWANLISAEFFRQGDRERRMNLPLAPTMDRYGITKPKVQTGFIRFLVRPLFNKWNEFMKTRLSEKMVQQLEQNLLRWE--LKQNQMAEKSD 1094
            +L K   W++DIF  DR+T+G+ +V L   L  +H L+  F++D +K    L +++ +YH +NPYHNA+HAADVTQAM+C++ + K+ +    +D ++ L+ A  HD+DHPGVNQ+FL KTN+YL+  YK  SVLENHH+R A+ +L E+ +F H T ++   ++ ++  +I+ATDI+RQNEYL QF T+    ++ +  A    +++ I+QMALKCADICNPCR W ++  W+  ++ EFF QGD ER+  L ++P  DR       +Q GFI +LV PLF +W  F  TRLS+ M+  +  N   W+  L++   +E++D
Sbjct:   18 MLEKVGSWSFDIFLFDRLTNGNSLVTLTFHLLSHHGLIDHFQLDMVKLRRFLVMVQEDYHSQNPYHNAVHAADVTQAMYCFLKEPKLAKSFTPWDILLGLIAAATHDLDHPGVNQSFLIKTNHYLATLYKNTSVLENHHWRSAVGLLRESGLFAHMTLEERQHMEGQLGSIILATDISRQNEYLSQFRTHLDRGDLCLDNA---SDRLFILQMALKCADICNPCRTWELSKQWSEKVTEEFFYQGDVERKYKLDVSPLCDRQTSNIANIQIGFITYLVEPLFVEWARFSNTRLSQTMLGHVGLNKASWKGMLQERSSSEEAD 336
[Close]
BLAST of Phosphodiesterase vs. Ensembl Xenopus
Match: PDE7A (phosphodiesterase 7A [Source:NCBI gene;Acc:100498541])

HSP 1 Score: 295.819 bits (756), Expect = 1.169e-95
Identity = 140/336 (41.67%), Postives = 220/336 (65.48%), Query Frame = 3 
Query:   93 VLDSEYFGIDKKRQLLLLKSVRWNYDIFTLDRITSGHPIVHLGMFLFEYHNLLTSFKIDYLKFLHTLTLLENNYHQKNPYHNALHAADVTQAMHCYVSDSKIRQKMKQFDFMVSLLGAMFHDVDHPGVNQAFLEKTNNYLSEFYKAQSVLENHHYRMALSILHETRVFHHFTTKQWGELQYRMYKLIMATDIARQNEYLDQFTNFIEQ-NIGIKEAFTKENKILIMQMALKCADICNPCREWRVAACWANLISAEFFRQGDRERRMNLPLAPTMDRYGITKPKVQTGFIRFLVRPLFNKWNEFMKTRLSEKMVQQLEQNLLRWE--LKQNQMAEKS 1091
            +LD +Y G   + + +L K   W++DIF  DR+T+G+ +V L   L  +H L+  F++D +K    L +++ +YH +NPYHNA+HAADVTQAM+C++ + K+ +    +D ++ L+ A  HD+DHPGVNQ+FL KTN+YL+  YK  SVLENHH+R A+ +L E+ +F H T ++   ++ ++  +I+ATDI+RQNEYL QF   +++ ++ +  A    +++ I+QMALKCADICNPCR W ++  W+  ++ EFF QGD ER+  L ++P  DR       +Q GFI +LV PLF +W  F  TRLS+ M+  +  N   W+  L++   +E++
Sbjct:  135 ILDDDYNG---QAKCMLEKVGSWSFDIFLFDRLTNGNSLVTLTFHLLSHHGLIDHFQLDMVKLRRFLVMVQEDYHSQNPYHNAVHAADVTQAMYCFLKEPKLAKSFTPWDILLGLIAAATHDLDHPGVNQSFLIKTNHYLATLYKNTSVLENHHWRSAVGLLRESGLFAHMTLEERQHMEGQLGSIILATDISRQNEYLSQFRTHLDRGDLCLDNA---SDRLFILQMALKCADICNPCRTWELSKQWSEKVTEEFFYQGDVERKYKLDVSPLCDRQTSNIANIQIGFITYLVEPLFVEWARFSNTRLSQTMLGHVGLNKASWKGMLQERSSSEET 464
[Close]
BLAST of Phosphodiesterase vs. Ensembl Mouse
Match: Pde7a (phosphodiesterase 7A [Source:MGI Symbol;Acc:MGI:1202402])

HSP 1 Score: 302.368 bits (773), Expect = 1.849e-98
Identity = 144/334 (43.11%), Postives = 213/334 (63.77%), Query Frame = 3 
Query:   93 VLDSEYFGIDKKRQLLLLKSVRWNYDIFTLDRITSGHPIVHLGMFLFEYHNLLTSFKIDYLKFLHTLTLLENNYHQKNPYHNALHAADVTQAMHCYVSDSKIRQKMKQFDFMVSLLGAMFHDVDHPGVNQAFLEKTNNYLSEFYKAQSVLENHHYRMALSILHETRVFHHFTTKQWGELQYRMYKLIMATDIARQNEYLDQFTNFIEQNIGIKEAFTKENKILIMQMALKCADICNPCREWRVAACWANLISAEFFRQGDRERRMNLPLAPTMDRYGITKPKVQTGFIRFLVRPLFNKWNEFMKTRLSEKMVQQLEQNLLRWELKQNQMAEKSD 1094
            +LD +Y G   + + +L K   WN+DIF  DR+T+G+ +V L   LF  H L+  F +D +K    L +++ +YH +NPYHNA+HAADVTQAMHCY+ + K+   +  +D ++SL+ A  HD+DHPGVNQ FL KTN+YL+  YK  SVLENHH+R A+ +L E+ +F H   +   E++ ++  LI+ATDI+RQNEYL  F + +++  G        ++ L++QMALKCADICNPCR W ++  W+  ++ EFF QGD E++ +L ++P  DR   +   +Q GF+ +LV PLF +W  F  TRLS+ M+  +  N   W+  Q Q     D
Sbjct:  109 ILDEDYNG---QAKCMLEKVGNWNFDIFLFDRLTNGNSLVSLTFHLFSLHGLIEYFHLDMVKLRRFLVMIQEDYHSQNPYHNAVHAADVTQAMHCYLKEPKLASSVTPWDILLSLIAAATHDLDHPGVNQPFLIKTNHYLATLYKNSSVLENHHWRSAVGLLRESGLFSHLPLESRQEMEAQIGALILATDISRQNEYLSLFRSHLDK--GDLHLDDGRHRHLVLQMALKCADICNPCRNWELSKQWSEKVTEEFFHQGDIEKKYHLGVSPLCDRQTESIANIQIGFMTYLVEPLFTEWARFSDTRLSQTMLGHVGLNKASWKGLQRQQPSSED 437
[Close]
BLAST of Phosphodiesterase vs. Ensembl Mouse
Match: Pde7a (phosphodiesterase 7A [Source:MGI Symbol;Acc:MGI:1202402])

HSP 1 Score: 302.368 bits (773), Expect = 4.128e-98
Identity = 144/334 (43.11%), Postives = 213/334 (63.77%), Query Frame = 3 
Query:   93 VLDSEYFGIDKKRQLLLLKSVRWNYDIFTLDRITSGHPIVHLGMFLFEYHNLLTSFKIDYLKFLHTLTLLENNYHQKNPYHNALHAADVTQAMHCYVSDSKIRQKMKQFDFMVSLLGAMFHDVDHPGVNQAFLEKTNNYLSEFYKAQSVLENHHYRMALSILHETRVFHHFTTKQWGELQYRMYKLIMATDIARQNEYLDQFTNFIEQNIGIKEAFTKENKILIMQMALKCADICNPCREWRVAACWANLISAEFFRQGDRERRMNLPLAPTMDRYGITKPKVQTGFIRFLVRPLFNKWNEFMKTRLSEKMVQQLEQNLLRWELKQNQMAEKSD 1094
            +LD +Y G   + + +L K   WN+DIF  DR+T+G+ +V L   LF  H L+  F +D +K    L +++ +YH +NPYHNA+HAADVTQAMHCY+ + K+   +  +D ++SL+ A  HD+DHPGVNQ FL KTN+YL+  YK  SVLENHH+R A+ +L E+ +F H   +   E++ ++  LI+ATDI+RQNEYL  F + +++  G        ++ L++QMALKCADICNPCR W ++  W+  ++ EFF QGD E++ +L ++P  DR   +   +Q GF+ +LV PLF +W  F  TRLS+ M+  +  N   W+  Q Q     D
Sbjct:  135 ILDEDYNG---QAKCMLEKVGNWNFDIFLFDRLTNGNSLVSLTFHLFSLHGLIEYFHLDMVKLRRFLVMIQEDYHSQNPYHNAVHAADVTQAMHCYLKEPKLASSVTPWDILLSLIAAATHDLDHPGVNQPFLIKTNHYLATLYKNSSVLENHHWRSAVGLLRESGLFSHLPLESRQEMEAQIGALILATDISRQNEYLSLFRSHLDK--GDLHLDDGRHRHLVLQMALKCADICNPCRNWELSKQWSEKVTEEFFHQGDIEKKYHLGVSPLCDRQTESIANIQIGFMTYLVEPLFTEWARFSDTRLSQTMLGHVGLNKASWKGLQRQQPSSED 463
[Close]
BLAST of Phosphodiesterase vs. Ensembl Mouse
Match: Pde7b (phosphodiesterase 7B [Source:MGI Symbol;Acc:MGI:1352752])

HSP 1 Score: 280.411 bits (716), Expect = 4.479e-90
Identity = 141/358 (39.39%), Postives = 221/358 (61.73%), Query Frame = 3 
Query:   93 VLDSEYFGIDKKRQLLLLKSVRWNYDIFTLDRITSGHPIVHLGMFLFEYHNLLTSFKIDYLKFLHTLTLLENNYHQKNPYHNALHAADVTQAMHCYVSDSKIRQKMKQFDFMVSLLGAMFHDVDHPGVNQAFLEKTNNYLSEFYKAQSVLENHHYRMALSILHETRVFHHFTTKQWGELQYRMYKLIMATDIARQNEYLDQFTNFIE-QNIGIKEAFTKENKILIMQMALKCADICNPCREWRVAACWANLISAEFFRQGDRERRMNLPLAPTMDRYGITKPKVQTGFIRFLVRPLFNKWNEFM-KTRLSEKMVQQLEQNLLRWE-LKQNQMAEKSDMLGED-AKPVSQTIPKTTAAV 1154
            +LD +Y G   + + +L K   W++DIF  DR+T+G+ +V L   LF  H L+  FK+D +     L +++ +YH  NPYHNA+HAADVTQAMHCY+ + K+   +   D M+ LL A  HDVDHPGVNQ FL KTN++L+  Y+  SVLENHH+R  + +L E+R+  H   +   +++ ++  LI+ATDI RQNE+L +    +  +++ ++     +++  ++Q+ALKCADICNPCR W ++  W+  +  EF+RQGD E++  L ++P  ++   + P +Q GF+ ++V PLF +W  F   + LSE M+  L  N  +W+ L  NQ   +    G+D A P  +T+ +T  A 
Sbjct:   96 LLDEDYLG---QARHMLSKVGTWDFDIFLFDRLTNGNSLVTLLCHLFNSHGLIHHFKLDMVTLHRFLVMVQEDYHGHNPYHNAVHAADVTQAMHCYLKEPKLASFLTPLDIMLGLLAAAAHDVDHPGVNQPFLIKTNHHLANLYQNMSVLENHHWRSTIGMLRESRLLAHLPKEMTQDIEQQLGSLILATDINRQNEFLTRLKAHLHNKDLRLENV---QDRHFMLQIALKCADICNPCRIWEMSKQWSERVCEEFYRQGDLEQKFELEISPLCNQQKDSIPSIQIGFMTYIVEPLFREWARFTGNSTLSENMLSHLAHNKAQWKSLLSNQHRRRGS--GQDLAGPAPETLEQTEGAT 445
[Close]
BLAST of Phosphodiesterase vs. Ensembl Mouse
Match: Pde7b (phosphodiesterase 7B [Source:MGI Symbol;Acc:MGI:1352752])

HSP 1 Score: 280.796 bits (717), Expect = 4.915e-90
Identity = 141/358 (39.39%), Postives = 221/358 (61.73%), Query Frame = 3 
Query:   93 VLDSEYFGIDKKRQLLLLKSVRWNYDIFTLDRITSGHPIVHLGMFLFEYHNLLTSFKIDYLKFLHTLTLLENNYHQKNPYHNALHAADVTQAMHCYVSDSKIRQKMKQFDFMVSLLGAMFHDVDHPGVNQAFLEKTNNYLSEFYKAQSVLENHHYRMALSILHETRVFHHFTTKQWGELQYRMYKLIMATDIARQNEYLDQFTNFIE-QNIGIKEAFTKENKILIMQMALKCADICNPCREWRVAACWANLISAEFFRQGDRERRMNLPLAPTMDRYGITKPKVQTGFIRFLVRPLFNKWNEFM-KTRLSEKMVQQLEQNLLRWE-LKQNQMAEKSDMLGED-AKPVSQTIPKTTAAV 1154
            +LD +Y G   + + +L K   W++DIF  DR+T+G+ +V L   LF  H L+  FK+D +     L +++ +YH  NPYHNA+HAADVTQAMHCY+ + K+   +   D M+ LL A  HDVDHPGVNQ FL KTN++L+  Y+  SVLENHH+R  + +L E+R+  H   +   +++ ++  LI+ATDI RQNE+L +    +  +++ ++     +++  ++Q+ALKCADICNPCR W ++  W+  +  EF+RQGD E++  L ++P  ++   + P +Q GF+ ++V PLF +W  F   + LSE M+  L  N  +W+ L  NQ   +    G+D A P  +T+ +T  A 
Sbjct:  109 LLDEDYLG---QARHMLSKVGTWDFDIFLFDRLTNGNSLVTLLCHLFNSHGLIHHFKLDMVTLHRFLVMVQEDYHGHNPYHNAVHAADVTQAMHCYLKEPKLASFLTPLDIMLGLLAAAAHDVDHPGVNQPFLIKTNHHLANLYQNMSVLENHHWRSTIGMLRESRLLAHLPKEMTQDIEQQLGSLILATDINRQNEFLTRLKAHLHNKDLRLENV---QDRHFMLQIALKCADICNPCRIWEMSKQWSERVCEEFYRQGDLEQKFELEISPLCNQQKDSIPSIQIGFMTYIVEPLFREWARFTGNSTLSENMLSHLAHNKAQWKSLLSNQHRRRGS--GQDLAGPAPETLEQTEGAT 458
[Close]
BLAST of Phosphodiesterase vs. Ensembl Mouse
Match: Pde7b (phosphodiesterase 7B [Source:MGI Symbol;Acc:MGI:1352752])

HSP 1 Score: 280.026 bits (715), Expect = 2.784e-89
Identity = 141/358 (39.39%), Postives = 221/358 (61.73%), Query Frame = 3 
Query:   93 VLDSEYFGIDKKRQLLLLKSVRWNYDIFTLDRITSGHPIVHLGMFLFEYHNLLTSFKIDYLKFLHTLTLLENNYHQKNPYHNALHAADVTQAMHCYVSDSKIRQKMKQFDFMVSLLGAMFHDVDHPGVNQAFLEKTNNYLSEFYKAQSVLENHHYRMALSILHETRVFHHFTTKQWGELQYRMYKLIMATDIARQNEYLDQFTNFIE-QNIGIKEAFTKENKILIMQMALKCADICNPCREWRVAACWANLISAEFFRQGDRERRMNLPLAPTMDRYGITKPKVQTGFIRFLVRPLFNKWNEFM-KTRLSEKMVQQLEQNLLRWE-LKQNQMAEKSDMLGED-AKPVSQTIPKTTAAV 1154
            +LD +Y G   + + +L K   W++DIF  DR+T+G+ +V L   LF  H L+  FK+D +     L +++ +YH  NPYHNA+HAADVTQAMHCY+ + K+   +   D M+ LL A  HDVDHPGVNQ FL KTN++L+  Y+  SVLENHH+R  + +L E+R+  H   +   +++ ++  LI+ATDI RQNE+L +    +  +++ ++     +++  ++Q+ALKCADICNPCR W ++  W+  +  EF+RQGD E++  L ++P  ++   + P +Q GF+ ++V PLF +W  F   + LSE M+  L  N  +W+ L  NQ   +    G+D A P  +T+ +T  A 
Sbjct:  148 LLDEDYLG---QARHMLSKVGTWDFDIFLFDRLTNGNSLVTLLCHLFNSHGLIHHFKLDMVTLHRFLVMVQEDYHGHNPYHNAVHAADVTQAMHCYLKEPKLASFLTPLDIMLGLLAAAAHDVDHPGVNQPFLIKTNHHLANLYQNMSVLENHHWRSTIGMLRESRLLAHLPKEMTQDIEQQLGSLILATDINRQNEFLTRLKAHLHNKDLRLENV---QDRHFMLQIALKCADICNPCRIWEMSKQWSERVCEEFYRQGDLEQKFELEISPLCNQQKDSIPSIQIGFMTYIVEPLFREWARFTGNSTLSENMLSHLAHNKAQWKSLLSNQHRRRGS--GQDLAGPAPETLEQTEGAT 497
[Close]
BLAST of Phosphodiesterase vs. UniProt/SwissProt
Match: sp|P70453|PDE7A_MOUSE (High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A OS=Mus musculus OX=10090 GN=Pde7a PE=2 SV=2)

HSP 1 Score: 302.368 bits (773), Expect = 1.293e-97
Identity = 144/334 (43.11%), Postives = 213/334 (63.77%), Query Frame = 3 
Query:   93 VLDSEYFGIDKKRQLLLLKSVRWNYDIFTLDRITSGHPIVHLGMFLFEYHNLLTSFKIDYLKFLHTLTLLENNYHQKNPYHNALHAADVTQAMHCYVSDSKIRQKMKQFDFMVSLLGAMFHDVDHPGVNQAFLEKTNNYLSEFYKAQSVLENHHYRMALSILHETRVFHHFTTKQWGELQYRMYKLIMATDIARQNEYLDQFTNFIEQNIGIKEAFTKENKILIMQMALKCADICNPCREWRVAACWANLISAEFFRQGDRERRMNLPLAPTMDRYGITKPKVQTGFIRFLVRPLFNKWNEFMKTRLSEKMVQQLEQNLLRWELKQNQMAEKSD 1094
            +LD +Y G   + + +L K   WN+DIF  DR+T+G+ +V L   LF  H L+  F +D +K    L +++ +YH +NPYHNA+HAADVTQAMHCY+ + K+   +  +D ++SL+ A  HD+DHPGVNQ FL KTN+YL+  YK  SVLENHH+R A+ +L E+ +F H   +   E++ ++  LI+ATDI+RQNEYL  F + +++  G        ++ L++QMALKCADICNPCR W ++  W+  ++ EFF QGD E++ +L ++P  DR   +   +Q GF+ +LV PLF +W  F  TRLS+ M+  +  N   W+  Q Q     D
Sbjct:  109 ILDEDYNG---QAKCMLEKVGNWNFDIFLFDRLTNGNSLVSLTFHLFSLHGLIEYFHLDMVKLRRFLVMIQEDYHSQNPYHNAVHAADVTQAMHCYLKEPKLASSVTPWDILLSLIAAATHDLDHPGVNQPFLIKTNHYLATLYKNSSVLENHHWRSAVGLLRESGLFSHLPLESRQEMEAQIGALILATDISRQNEYLSLFRSHLDK--GDLHLDDGRHRHLVLQMALKCADICNPCRNWELSKQWSEKVTEEFFHQGDIEKKYHLGVSPLCDRQTESIANIQIGFMTYLVEPLFTEWARFSDTRLSQTMLGHVGLNKASWKGLQRQQPSSED 437
[Close]
BLAST of Phosphodiesterase vs. UniProt/SwissProt
Match: sp|Q13946|PDE7A_HUMAN (High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A OS=Homo sapiens OX=9606 GN=PDE7A PE=1 SV=2)

HSP 1 Score: 301.212 bits (770), Expect = 8.127e-97
Identity = 142/334 (42.51%), Postives = 215/334 (64.37%), Query Frame = 3 
Query:   93 VLDSEYFGIDKKRQLLLLKSVRWNYDIFTLDRITSGHPIVHLGMFLFEYHNLLTSFKIDYLKFLHTLTLLENNYHQKNPYHNALHAADVTQAMHCYVSDSKIRQKMKQFDFMVSLLGAMFHDVDHPGVNQAFLEKTNNYLSEFYKAQSVLENHHYRMALSILHETRVFHHFTTKQWGELQYRMYKLIMATDIARQNEYLDQFTNFIEQNIGIKEAFTKENKILIMQMALKCADICNPCREWRVAACWANLISAEFFRQGDRERRMNLPLAPTMDRYGITKPKVQTGFIRFLVRPLFNKWNEFMKTRLSEKMVQQLEQNLLRWELKQNQMAEKSD 1094
            +LD +Y G   + + +L K   WN+DIF  DR+T+G+ +V L   LF  H L+  F +D +K    L +++ +YH +NPYHNA+HAADVTQAMHCY+ + K+   +  +D ++SL+ A  HD+DHPGVNQ FL KTN+YL+  YK  SVLENHH+R A+ +L E+ +F H   +   +++ ++  LI+ATDI+RQNEYL  F + +++     E     ++ L++QMALKCADICNPCR W ++  W+  ++ EFF QGD E++ +L ++P  DR+  +   +Q GF+ +LV PLF +W  F  TRLS+ M+  +  N   W+  Q + +   D
Sbjct:  135 ILDDDYNG---QAKCMLEKVGNWNFDIFLFDRLTNGNSLVSLTFHLFSLHGLIEYFHLDMMKLRRFLVMIQEDYHSQNPYHNAVHAADVTQAMHCYLKEPKLANSVTPWDILLSLIAAATHDLDHPGVNQPFLIKTNHYLATLYKNTSVLENHHWRSAVGLLRESGLFSHLPLESRQQMETQIGALILATDISRQNEYLSLFRSHLDRGDLCLE--DTRHRHLVLQMALKCADICNPCRTWELSKQWSEKVTEEFFHQGDIEKKYHLGVSPLCDRHTESIANIQIGFMTYLVEPLFTEWARFSNTRLSQTMLGHVGLNKASWKGLQREQSSSED 463
[Close]
BLAST of Phosphodiesterase vs. UniProt/SwissProt
Match: sp|O08593|PDE7A_RAT (High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A (Fragment) OS=Rattus norvegicus OX=10116 GN=Pde7a PE=2 SV=1)

HSP 1 Score: 298.901 bits (764), Expect = 1.303e-96
Identity = 143/334 (42.81%), Postives = 212/334 (63.47%), Query Frame = 3 
Query:   93 VLDSEYFGIDKKRQLLLLKSVRWNYDIFTLDRITSGHPIVHLGMFLFEYHNLLTSFKIDYLKFLHTLTLLENNYHQKNPYHNALHAADVTQAMHCYVSDSKIRQKMKQFDFMVSLLGAMFHDVDHPGVNQAFLEKTNNYLSEFYKAQSVLENHHYRMALSILHETRVFHHFTTKQWGELQYRMYKLIMATDIARQNEYLDQFTNFIEQNIGIKEAFTKENKILIMQMALKCADICNPCREWRVAACWANLISAEFFRQGDRERRMNLPLAPTMDRYGITKPKVQTGFIRFLVRPLFNKWNEFMKTRLSEKMVQQLEQNLLRWELKQNQMAEKSD 1094
            +LD +Y G   + + +L K   WN+DIF  DR+T+G+ +V L   LF  H L+  F +D +K    L +++ +YH +NPYHNA+HAADVTQAMHCY+ + K+   +  +D ++SL+ A  HD+DHPGVNQ FL KTN+YL+  YK  SVLENHH+R A+ +L E+ +F H   +   E++ ++  LI+ATDI+RQNEYL  F + +++  G        ++ L++QMALKCADICNPCR W ++  W+  ++ EFF QGD E++ +L ++P  DR   +   +Q GF+ +L  PLF +W  F  TRLS+ M+  +  N   W+  Q Q     D
Sbjct:   79 ILDEDYNG---QAKCMLEKVGNWNFDIFLFDRLTNGNSLVSLTFHLFSLHGLIEYFHLDMVKLRRFLVMIQEDYHSQNPYHNAVHAADVTQAMHCYLKEPKLANSVTPWDILLSLIAAATHDLDHPGVNQPFLIKTNHYLATLYKNTSVLENHHWRSAVGLLRESGLFSHLPLESRHEMEAQIGALILATDISRQNEYLSLFRSHLDK--GDLHLDDGRHRHLVLQMALKCADICNPCRNWELSKQWSEKVTEEFFHQGDIEKKYHLGVSPLCDRQTESIANIQIGFMTYLQEPLFTEWARFSDTRLSQTMLGHVGLNKASWKGLQRQQPSSED 407
[Close]
BLAST of Phosphodiesterase vs. UniProt/SwissProt
Match: sp|Q9QXQ1|PDE7B_MOUSE (cAMP-specific 3',5'-cyclic phosphodiesterase 7B OS=Mus musculus OX=10090 GN=Pde7b PE=1 SV=1)

HSP 1 Score: 280.411 bits (716), Expect = 3.133e-89
Identity = 141/358 (39.39%), Postives = 221/358 (61.73%), Query Frame = 3 
Query:   93 VLDSEYFGIDKKRQLLLLKSVRWNYDIFTLDRITSGHPIVHLGMFLFEYHNLLTSFKIDYLKFLHTLTLLENNYHQKNPYHNALHAADVTQAMHCYVSDSKIRQKMKQFDFMVSLLGAMFHDVDHPGVNQAFLEKTNNYLSEFYKAQSVLENHHYRMALSILHETRVFHHFTTKQWGELQYRMYKLIMATDIARQNEYLDQFTNFIE-QNIGIKEAFTKENKILIMQMALKCADICNPCREWRVAACWANLISAEFFRQGDRERRMNLPLAPTMDRYGITKPKVQTGFIRFLVRPLFNKWNEFM-KTRLSEKMVQQLEQNLLRWE-LKQNQMAEKSDMLGED-AKPVSQTIPKTTAAV 1154
            +LD +Y G   + + +L K   W++DIF  DR+T+G+ +V L   LF  H L+  FK+D +     L +++ +YH  NPYHNA+HAADVTQAMHCY+ + K+   +   D M+ LL A  HDVDHPGVNQ FL KTN++L+  Y+  SVLENHH+R  + +L E+R+  H   +   +++ ++  LI+ATDI RQNE+L +    +  +++ ++     +++  ++Q+ALKCADICNPCR W ++  W+  +  EF+RQGD E++  L ++P  ++   + P +Q GF+ ++V PLF +W  F   + LSE M+  L  N  +W+ L  NQ   +    G+D A P  +T+ +T  A 
Sbjct:   96 LLDEDYLG---QARHMLSKVGTWDFDIFLFDRLTNGNSLVTLLCHLFNSHGLIHHFKLDMVTLHRFLVMVQEDYHGHNPYHNAVHAADVTQAMHCYLKEPKLASFLTPLDIMLGLLAAAAHDVDHPGVNQPFLIKTNHHLANLYQNMSVLENHHWRSTIGMLRESRLLAHLPKEMTQDIEQQLGSLILATDINRQNEFLTRLKAHLHNKDLRLENV---QDRHFMLQIALKCADICNPCRIWEMSKQWSERVCEEFYRQGDLEQKFELEISPLCNQQKDSIPSIQIGFMTYIVEPLFREWARFTGNSTLSENMLSHLAHNKAQWKSLLSNQHRRRGS--GQDLAGPAPETLEQTEGAT 445
[Close]
BLAST of Phosphodiesterase vs. UniProt/SwissProt
Match: sp|Q9NP56|PDE7B_HUMAN (cAMP-specific 3',5'-cyclic phosphodiesterase 7B OS=Homo sapiens OX=9606 GN=PDE7B PE=1 SV=1)

HSP 1 Score: 275.404 bits (703), Expect = 3.090e-87
Identity = 136/349 (38.97%), Postives = 216/349 (61.89%), Query Frame = 3 
Query:   93 VLDSEYFGIDKKRQLLLLKSVRWNYDIFTLDRITSGHPIVHLGMFLFEYHNLLTSFKIDYLKFLHTLTLLENNYHQKNPYHNALHAADVTQAMHCYVSDSKIRQKMKQFDFMVSLLGAMFHDVDHPGVNQAFLEKTNNYLSEFYKAQSVLENHHYRMALSILHETRVFHHFTTKQWGELQYRMYKLIMATDIARQNEYLDQFTNFI-EQNIGIKEAFTKENKILIMQMALKCADICNPCREWRVAACWANLISAEFFRQGDRERRMNLPLAPTMDRYGITKPKVQTGFIRFLVRPLFNKWNEFM-KTRLSEKMVQQLEQNLLRWE--LKQNQMAEKSDMLGEDAKPVSQ 1127
            +LD +Y G   + + +L K   W++DIF  DR+T+G+ +V L   LF  H L+  FK+D +     L +++ +YH +NPYHNA+HAADVTQAMHCY+ + K+   +   D M+ LL A  HDVDHPGVNQ FL KTN++L+  Y+  SVLENHH+R  + +L E+R+  H   +   +++ ++  LI+ATDI RQNE+L +    +  +++ +++A   +++  ++Q+ALKCADICNPCR W ++  W+  +  EF+RQG+ E++  L ++P  ++   + P +Q GF+ ++V PLF +W  F   + LSE M+  L  N  +W+  L +   +  S   G D     Q
Sbjct:   96 LLDEDYLG---QARHMLSKVGMWDFDIFLFDRLTNGNSLVTLLCHLFNTHGLIHHFKLDMVTLHRFLVMVQEDYHSQNPYHNAVHAADVTQAMHCYLKEPKLASFLTPLDIMLGLLAAAAHDVDHPGVNQPFLIKTNHHLANLYQNMSVLENHHWRSTIGMLRESRLLAHLPKEMTQDIEQQLGSLILATDINRQNEFLTRLKAHLHNKDLRLEDA---QDRHFMLQIALKCADICNPCRIWEMSKQWSERVCEEFYRQGELEQKFELEISPLCNQQKDSIPSIQIGFMSYIVEPLFREWAHFTGNSTLSENMLGHLAHNKAQWKSLLPRQHRSRGSSGSGPDHDHAGQ 438
[Close]
BLAST of Phosphodiesterase vs. TrEMBL
Match: A0A4E0RI82 (High affinity cAMP-specific 3' 5'-cyclic phosphodiesterase 7A isoform X1 OS=Fasciola hepatica OX=6192 GN=D915_000691 PE=3 SV=1)

HSP 1 Score: 316.62 bits (810), Expect = 9.669e-102
Identity = 142/303 (46.86%), Postives = 212/303 (69.97%), Query Frame = 3 
Query:  159 WNYDIFTLDRITSGHPIVHLGMFLFEYHNLLTSFKIDYLKFLHTLTLLENNYHQKNPYHNALHAADVTQAMHCYVSDSKIRQKMKQFDFMVSLLGAMFHDVDHPGVNQAFLEKTNNYLSEFYKAQSVLENHHYRMALSILHETRVFHHFTTKQWGELQYRMYKLIMATDIARQNEYLDQFTNFIE--QNIGIKEAFTKENKILIMQMALKCADICNPCREWRVAACWANLISAEFFRQGDRERRMNLPLAPTMDRYGITKPKVQTGFIRFLVRPLFNKWNEFMKTRLSEKMVQQLEQNLLRWE 1061
            WN++IF+++R+T+GHPI+ LG+++FE + L+  FKID L  ++T  +LEN+YHQ N +HNA+HAADV QA  C + D + R+ +  FDF  S L A  HD+DHPGVNQ++LEKT+++L+EFY+  SVLENHH+R  +S+L +T++ +  ++++W E   R+  LI++TDI RQ  Y++ F  F+   +N G      K+  +L+ QM LKCAD+ NPCR W     WANL++ EFFRQGD+E+   L + PTMDR   TK K+QT FI+F+V PL   W+ F++++LS  MV++  +NL  W+
Sbjct:   53 WNFNIFSIERLTNGHPILGLGLYIFERYKLIEKFKIDTLVLVNTFRILENSYHQDNVFHNAIHAADVVQASLCLLRDLRNRKVISNFDFACSTLAAFGHDLDHPGVNQSYLEKTDDFLAEFYQHSSVLENHHFRSTVSVLQKTKLLNSLSSEKWQEFVRRLKLLILSTDITRQQHYVEHFKTFLNTIENSGRWNDTVKQEIVLVQQMVLKCADVSNPCRNWESYVTWANLVTEEFFRQGDQEKERGLHVFPTMDRLLTTKQKIQTNFIQFIVLPLIELWDSFIQSKLSGYMVKKCYRNLHVWQ 355
[Close]
BLAST of Phosphodiesterase vs. TrEMBL
Match: A0A504YUZ9 (Phosphodiesterase OS=Fasciola gigantica OX=46835 GN=FGIG_10839 PE=3 SV=1)

HSP 1 Score: 315.464 bits (807), Expect = 3.119e-101
Identity = 142/303 (46.86%), Postives = 210/303 (69.31%), Query Frame = 3 
Query:  159 WNYDIFTLDRITSGHPIVHLGMFLFEYHNLLTSFKIDYLKFLHTLTLLENNYHQKNPYHNALHAADVTQAMHCYVSDSKIRQKMKQFDFMVSLLGAMFHDVDHPGVNQAFLEKTNNYLSEFYKAQSVLENHHYRMALSILHETRVFHHFTTKQWGELQYRMYKLIMATDIARQNEYLDQFTNFIE--QNIGIKEAFTKENKILIMQMALKCADICNPCREWRVAACWANLISAEFFRQGDRERRMNLPLAPTMDRYGITKPKVQTGFIRFLVRPLFNKWNEFMKTRLSEKMVQQLEQNLLRWE 1061
            WN++IF+++R+T GHPI+ LG+++FE + L+  FKID L   +T  +LEN+YHQ N +HNA+HAADV QA  C + D + R+ +  FDF  S L A  HD+DHPGVNQ++LEKT+++L+EFY+  SVLENHH+R  +S+L +T++ +  ++++W E   R+  LI++TDI RQ  Y++ F  F+   +N G      K+  +L+ QM LKCAD+ NPCR W     WANLI+ EFF+QGD+E+   L + PTMDR   TK K+QT FI+F+V PL   W+ F++++LS  MV++  +NL  W+
Sbjct:   53 WNFNIFSIERLTDGHPILGLGLYIFERYKLIEKFKIDTLVLFNTFRILENSYHQDNVFHNAIHAADVVQASLCLLRDLRNRKVISNFDFACSTLAAFGHDLDHPGVNQSYLEKTDDFLAEFYQHSSVLENHHFRSTVSVLQKTKLLNSLSSEKWQEFVRRLKLLILSTDITRQQHYVEHFKTFLNTIENSGRWNDTVKQEIVLVQQMVLKCADVSNPCRNWESYVTWANLITEEFFKQGDQEKERGLHVFPTMDRLLTTKQKIQTNFIQFIVLPLIELWDSFIQSKLSGYMVKKCYRNLHVWQ 355
[Close]
BLAST of Phosphodiesterase vs. TrEMBL
Match: A0A068WL13 (High affinity cAMP specific 3'5' cyclic OS=Echinococcus granulosus OX=6210 GN=EgrG_000613600 PE=3 SV=1)

HSP 1 Score: 313.153 bits (801), Expect = 1.107e-100
Identity = 148/333 (44.44%), Postives = 220/333 (66.07%), Query Frame = 3 
Query:   63 KPPRRIDIYGVLDSEYFGIDKKRQLLLLKSVRWNYDIFTLDRITSGHPIVHLGMFLFEYHNLLTSFKIDYLKFLHTLTLLENNYHQKNPYHNALHAADVTQAMHCYVSDSKIRQKMKQFDFMVSLLGAMFHDVDHPGVNQAFLEKTNNYLSEFYKAQSVLENHHYRMALSILHETRVFHHFTTKQWGELQYRMYKLIMATDIARQNEYLDQFTNFIEQNIGIKEAF-TKENKILIMQMALKCADICNPCREWRVAACWANLISAEFFRQGDRERRMNLPLAPTMDRYGITKPKVQTGFIRFLVRPLFNKWNEFMKTRLSEKMVQQLEQNLLRW 1058
            K  RR   +  L  E + +D  RQ LL   + WN+++FTL+R+T+G P++ +G +LFE       F +D+   +  L  +E+ YH+ NPYHNALHAADVTQA +C +   ++ + +  FDFM ++L A+ HD+DHPGVNQAFL KT   LS FY+ +S+LE+HH  + +S+L ++RVF  F+ ++WG +++ M +LI+ATDI++Q EYL+Q  +  E+    +    T E+  L+M+MA+KCADI NPCR W     WAN I+ EFF+QGDRE  + LP+ P MDR   TK KVQ GFI F V PLF +W+ +++++ S  +V + ++NL  W
Sbjct:   13 KDKRRPRYFRCLLDETYFVD--RQSLLQPLLHWNFNLFTLERLTAGFPLLAIGKYLFEKSKFFQKFHLDHFLVVRLLRQIEDLYHENNPYHNALHAADVTQATYCLLKRLRVEKSISAFDFMCAILAAICHDIDHPGVNQAFLIKTKQMLSIFYE-ESILEHHHSNVCISVLLQSRVFSAFSIRRWGAMKHYMKRLILATDISKQEEYLEQLESLTERRYPSENYLPTHEDITLVMEMAIKCADISNPCRHWETCQQWANCITEEFFQQGDRESLLGLPVMPLMDRNKTTKAKVQIGFIEFQVLPLFEQWDAYVRSKFSRSLVAKCKKNLAIW 342
[Close]
BLAST of Phosphodiesterase vs. TrEMBL
Match: A0A5K3F0I6 (Uncharacterized protein OS=Mesocestoides corti OX=53468 PE=4 SV=1)

HSP 1 Score: 310.457 bits (794), Expect = 1.558e-99
Identity = 147/343 (42.86%), Postives = 227/343 (66.18%), Query Frame = 3 
Query:   48 KRAGCKPPRRI-DIYGVLDSEYFGIDKKRQLLLLKSVRWNYDIFTLDRITSGHPIVHLGMFLFEYHNLLTSFKIDYLKFLHTLTLLENNYHQKNPYHNALHAADVTQAMHCYVSDSKIRQKMKQFDFMVSLLGAMFHDVDHPGVNQAFLEKTNNYLSEFYKAQSVLENHHYRMALSILHETRVFHHFTTKQWGELQYRMYKLIMATDIARQNEYLDQFTNFIEQNIGIKE-AFTKENKILIMQMALKCADICNPCREWRVAACWANLISAEFFRQGDRERRMNLPLAPTMDRYGITKPKVQTGFIRFLVRPLFNKWNEFMKTRLSEKMVQQLEQNLLRWELKQ 1070
            KR   K  R++ D   +LD  YF +D  R  LL  ++ W++++F+L+R+T+G P++ +G FLF+       F +DY   +     +E+ YH+ N YHNALHAADV QA++C + + ++ + +  F++M ++L A+ HD+DHPGVNQ+FL K+   LS FY + S+LENHH  +  S+L +++ F  F+T++W  L+  +  LI+ATDI RQ+E+L    +  E+  G ++   T +++ L+ Q+A+KCADI NPCR+W V+  WAN I+ EFF QGDRE  + LP+ PTM+R   TK KVQ GFI+FLV PLF KW+ +M+T+ S  +V++ ++NL  W  KQ
Sbjct:   19 KRDEWKKKRKLHDFRCLLDESYF-VD--RPSLLKPALHWSFNLFSLERLTAGFPLLAIGTFLFQKAKFFQKFHLDYFHVIRLFKHIEDLYHENNSYHNALHAADVAQAIYCLLKEQRVNKCISAFEYMCAILAAICHDIDHPGVNQSFLVKSKQMLSIFYTS-SLLENHHSNVTTSVLLQSKAFSDFSTRRWDALKANVKGLILATDITRQDEFLQNIQDLTERRYGQEDYVLTDDDRKLVTQVAIKCADISNPCRQWAVSLLWANCITEEFFLQGDRENLLGLPVLPTMNRKTTTKAKVQIGFIKFLVLPLFEKWDNYMRTKFSRALVEKCKKNLAIWTAKQ 357
[Close]
BLAST of Phosphodiesterase vs. TrEMBL
Match: A0A068Y1T0 (High affinity cAMP specific 3'5' cyclic OS=Echinococcus multilocularis OX=6211 PE=3 SV=1)

HSP 1 Score: 308.531 bits (789), Expect = 7.283e-99
Identity = 148/332 (44.58%), Postives = 219/332 (65.96%), Query Frame = 3 
Query:   96 LDSEYFGIDKKRQLLLLKSVRWNYDIFTLDRITSGHPIVHLGMFLFEYHNLLTSFKIDYLKFLHTLTLLENNYHQKNPYHNALHAADVTQAMHCYVSDSKIRQKMKQFDFMVSLLGAMFHDVDHPGVNQAFLEKTNNYLSEFYKAQSVLENHHYRMALSILHETRVFHHFTTKQWGELQYRMYKLIMATDIARQNEYLDQFTNFIEQNIGIKEAF-TKENKILIMQMALKCADICNPCREWRVAACWANLISAEFFRQGDRERRMNLPLAPTMDRYGITKPKVQTGFIRFLVRPLFNKWNEFMKTRLSEKMVQQLEQNLLRWELKQNQMAEK 1088
            LD  YF +D  RQ LL   + WN+++FTL+R+T+G P++ +G +LFE       F +D+   +  L  +E+ YH+ NPYHNALHAADVTQA +C +   ++ + +  FDFM ++L A+ HD+DHPGVNQAFL KT   LS FY+ +S+LE+HH  + +S+L ++RVF  F+ ++W  +++ M +LI+ATDI++Q EYL+Q  +  E+    +    T E+  L+M+MA+KCADI NPCR W     WAN I+ EFF+QGDRE  + LP+ P MDR   TK KVQ GFI F V PLF +W+ +++++ S  +V + ++NL  W  +     EK
Sbjct:   25 LDETYF-VD--RQSLLQPLLHWNFNLFTLERLTAGFPLLAIGKYLFEKSKFFQKFHLDHFLVVRLLRQIEDLYHENNPYHNALHAADVTQATYCLLKRLRVEKSISAFDFMCAILAAICHDIDHPGVNQAFLIKTKQMLSIFYE-ESILEHHHSNVCISVLLQSRVFSAFSIRRWEAMKHYMKRLILATDISKQEEYLEQLESLTERRYPSENYLPTHEDITLVMEMAIKCADISNPCRHWETCQQWANCITEEFFQQGDREILLGLPVMPLMDRNKTTKAKVQIGFIEFQVLPLFEQWDAYVRSKFSRSLVAKCKKNLAIWLARDAAANEK 352
[Close]
BLAST of Phosphodiesterase vs. Ensembl Cavefish
Match: pde7a (phosphodiesterase 7A [Source:NCBI gene;Acc:103042481])

HSP 1 Score: 291.967 bits (746), Expect = 5.624e-95
Identity = 140/331 (42.30%), Postives = 212/331 (64.05%), Query Frame = 3 
Query:   93 VLDSEYFGIDKKRQLLLLKSVRWNYDIFTLDRITSGHPIVHLGMFLFEYHNLLTSFKIDYLKFLHTLTLLENNYHQKNPYHNALHAADVTQAMHCYVSDSKIRQKMKQFDFMVSLLGAMFHDVDHPGVNQAFLEKTNNYLSEFYKAQSVLENHHYRMALSILHETRVFHHFTTKQWGELQYRMYKLIMATDIARQNEYLDQF-TNFIEQNIGIKEAFTKENKILIMQMALKCADICNPCREWRVAACWANLISAEFFRQGDRERRMNLPLAPTMDRYGITKPKVQTGFIRFLVRPLFNKWNEFMKTRLSEKMVQQLEQNLLRWELKQNQMA 1082
            +LD +Y G   + + +L K   WN+DIF  DR+T+G+ +V L ++L  ++ L+  F++D +K    L L++ +YH  NPYHNA+HAADVTQAMHCY+ + K+ + +   D ++ LL A  HD+DHPGVNQ FL KTN+YL+  Y+  SVLENHH+R A+ +L ET +  H   +    ++ ++  LI+ATDI+RQNEYL +F T+  ++++ +  A    ++  I+QMALKCADICNPCR W ++  W+  ++ EFF QGD E++  L ++P  D    +   VQ GF+ ++V PLF +W  F  TRLS+ M+  L  N   W   Q + +
Sbjct:   73 ILDEDYCG---QAKCMLEKVGSWNFDIFLFDRLTNGNSLVTLTLYLLSHYGLIELFQLDMVKVHRFLVLVQEDYHNHNPYHNAVHAADVTQAMHCYLKEPKLAKSLTSCDILLGLLAAATHDLDHPGVNQPFLIKTNHYLAVLYRNTSVLENHHWRSAVGLLRETELLSHLPAEDRLTMERQLGSLILATDISRQNEYLSKFRTHLDQEDLCLGNA---SHRHFILQMALKCADICNPCRPWELSKQWSEKVTEEFFHQGDIEKKHKLEVSPLCDSENNSIADVQIGFMTYVVEPLFAEWARFSDTRLSQTMLGHLCLNKASWNAMQPEAS 397
[Close]
BLAST of Phosphodiesterase vs. Ensembl Cavefish
Match: pde7a (phosphodiesterase 7A [Source:NCBI gene;Acc:103042481])

HSP 1 Score: 291.967 bits (746), Expect = 9.801e-95
Identity = 140/331 (42.30%), Postives = 212/331 (64.05%), Query Frame = 3 
Query:   93 VLDSEYFGIDKKRQLLLLKSVRWNYDIFTLDRITSGHPIVHLGMFLFEYHNLLTSFKIDYLKFLHTLTLLENNYHQKNPYHNALHAADVTQAMHCYVSDSKIRQKMKQFDFMVSLLGAMFHDVDHPGVNQAFLEKTNNYLSEFYKAQSVLENHHYRMALSILHETRVFHHFTTKQWGELQYRMYKLIMATDIARQNEYLDQF-TNFIEQNIGIKEAFTKENKILIMQMALKCADICNPCREWRVAACWANLISAEFFRQGDRERRMNLPLAPTMDRYGITKPKVQTGFIRFLVRPLFNKWNEFMKTRLSEKMVQQLEQNLLRWELKQNQMA 1082
            +LD +Y G   + + +L K   WN+DIF  DR+T+G+ +V L ++L  ++ L+  F++D +K    L L++ +YH  NPYHNA+HAADVTQAMHCY+ + K+ + +   D ++ LL A  HD+DHPGVNQ FL KTN+YL+  Y+  SVLENHH+R A+ +L ET +  H   +    ++ ++  LI+ATDI+RQNEYL +F T+  ++++ +  A    ++  I+QMALKCADICNPCR W ++  W+  ++ EFF QGD E++  L ++P  D    +   VQ GF+ ++V PLF +W  F  TRLS+ M+  L  N   W   Q + +
Sbjct:   84 ILDEDYCG---QAKCMLEKVGSWNFDIFLFDRLTNGNSLVTLTLYLLSHYGLIELFQLDMVKVHRFLVLVQEDYHNHNPYHNAVHAADVTQAMHCYLKEPKLAKSLTSCDILLGLLAAATHDLDHPGVNQPFLIKTNHYLAVLYRNTSVLENHHWRSAVGLLRETELLSHLPAEDRLTMERQLGSLILATDISRQNEYLSKFRTHLDQEDLCLGNA---SHRHFILQMALKCADICNPCRPWELSKQWSEKVTEEFFHQGDIEKKHKLEVSPLCDSENNSIADVQIGFMTYVVEPLFAEWARFSDTRLSQTMLGHLCLNKASWNAMQPEAS 408
[Close]
BLAST of Phosphodiesterase vs. Ensembl Cavefish
Match: pde7a (phosphodiesterase 7A [Source:NCBI gene;Acc:103042481])

HSP 1 Score: 291.967 bits (746), Expect = 2.092e-94
Identity = 140/331 (42.30%), Postives = 212/331 (64.05%), Query Frame = 3 
Query:   93 VLDSEYFGIDKKRQLLLLKSVRWNYDIFTLDRITSGHPIVHLGMFLFEYHNLLTSFKIDYLKFLHTLTLLENNYHQKNPYHNALHAADVTQAMHCYVSDSKIRQKMKQFDFMVSLLGAMFHDVDHPGVNQAFLEKTNNYLSEFYKAQSVLENHHYRMALSILHETRVFHHFTTKQWGELQYRMYKLIMATDIARQNEYLDQF-TNFIEQNIGIKEAFTKENKILIMQMALKCADICNPCREWRVAACWANLISAEFFRQGDRERRMNLPLAPTMDRYGITKPKVQTGFIRFLVRPLFNKWNEFMKTRLSEKMVQQLEQNLLRWELKQNQMA 1082
            +LD +Y G   + + +L K   WN+DIF  DR+T+G+ +V L ++L  ++ L+  F++D +K    L L++ +YH  NPYHNA+HAADVTQAMHCY+ + K+ + +   D ++ LL A  HD+DHPGVNQ FL KTN+YL+  Y+  SVLENHH+R A+ +L ET +  H   +    ++ ++  LI+ATDI+RQNEYL +F T+  ++++ +  A    ++  I+QMALKCADICNPCR W ++  W+  ++ EFF QGD E++  L ++P  D    +   VQ GF+ ++V PLF +W  F  TRLS+ M+  L  N   W   Q + +
Sbjct:  115 ILDEDYCG---QAKCMLEKVGSWNFDIFLFDRLTNGNSLVTLTLYLLSHYGLIELFQLDMVKVHRFLVLVQEDYHNHNPYHNAVHAADVTQAMHCYLKEPKLAKSLTSCDILLGLLAAATHDLDHPGVNQPFLIKTNHYLAVLYRNTSVLENHHWRSAVGLLRETELLSHLPAEDRLTMERQLGSLILATDISRQNEYLSKFRTHLDQEDLCLGNA---SHRHFILQMALKCADICNPCRPWELSKQWSEKVTEEFFHQGDIEKKHKLEVSPLCDSENNSIADVQIGFMTYVVEPLFAEWARFSDTRLSQTMLGHLCLNKASWNAMQPEAS 439
[Close]
BLAST of Phosphodiesterase vs. Ensembl Cavefish
Match: pde7a (phosphodiesterase 7A [Source:NCBI gene;Acc:103042481])

HSP 1 Score: 291.582 bits (745), Expect = 3.575e-94
Identity = 140/331 (42.30%), Postives = 212/331 (64.05%), Query Frame = 3 
Query:   93 VLDSEYFGIDKKRQLLLLKSVRWNYDIFTLDRITSGHPIVHLGMFLFEYHNLLTSFKIDYLKFLHTLTLLENNYHQKNPYHNALHAADVTQAMHCYVSDSKIRQKMKQFDFMVSLLGAMFHDVDHPGVNQAFLEKTNNYLSEFYKAQSVLENHHYRMALSILHETRVFHHFTTKQWGELQYRMYKLIMATDIARQNEYLDQF-TNFIEQNIGIKEAFTKENKILIMQMALKCADICNPCREWRVAACWANLISAEFFRQGDRERRMNLPLAPTMDRYGITKPKVQTGFIRFLVRPLFNKWNEFMKTRLSEKMVQQLEQNLLRWELKQNQMA 1082
            +LD +Y G   + + +L K   WN+DIF  DR+T+G+ +V L ++L  ++ L+  F++D +K    L L++ +YH  NPYHNA+HAADVTQAMHCY+ + K+ + +   D ++ LL A  HD+DHPGVNQ FL KTN+YL+  Y+  SVLENHH+R A+ +L ET +  H   +    ++ ++  LI+ATDI+RQNEYL +F T+  ++++ +  A    ++  I+QMALKCADICNPCR W ++  W+  ++ EFF QGD E++  L ++P  D    +   VQ GF+ ++V PLF +W  F  TRLS+ M+  L  N   W   Q + +
Sbjct:  122 ILDEDYCG---QAKCMLEKVGSWNFDIFLFDRLTNGNSLVTLTLYLLSHYGLIELFQLDMVKVHRFLVLVQEDYHNHNPYHNAVHAADVTQAMHCYLKEPKLAKSLTSCDILLGLLAAATHDLDHPGVNQPFLIKTNHYLAVLYRNTSVLENHHWRSAVGLLRETELLSHLPAEDRLTMERQLGSLILATDISRQNEYLSKFRTHLDQEDLCLGNA---SHRHFILQMALKCADICNPCRPWELSKQWSEKVTEEFFHQGDIEKKHKLEVSPLCDSENNSIADVQIGFMTYVVEPLFAEWARFSDTRLSQTMLGHLCLNKASWNAMQPEAS 446
[Close]
BLAST of Phosphodiesterase vs. Ensembl Cavefish
Match: pde7a (phosphodiesterase 7A [Source:NCBI gene;Acc:103042481])

HSP 1 Score: 291.967 bits (746), Expect = 5.531e-94
Identity = 140/331 (42.30%), Postives = 212/331 (64.05%), Query Frame = 3 
Query:   93 VLDSEYFGIDKKRQLLLLKSVRWNYDIFTLDRITSGHPIVHLGMFLFEYHNLLTSFKIDYLKFLHTLTLLENNYHQKNPYHNALHAADVTQAMHCYVSDSKIRQKMKQFDFMVSLLGAMFHDVDHPGVNQAFLEKTNNYLSEFYKAQSVLENHHYRMALSILHETRVFHHFTTKQWGELQYRMYKLIMATDIARQNEYLDQF-TNFIEQNIGIKEAFTKENKILIMQMALKCADICNPCREWRVAACWANLISAEFFRQGDRERRMNLPLAPTMDRYGITKPKVQTGFIRFLVRPLFNKWNEFMKTRLSEKMVQQLEQNLLRWELKQNQMA 1082
            +LD +Y G   + + +L K   WN+DIF  DR+T+G+ +V L ++L  ++ L+  F++D +K    L L++ +YH  NPYHNA+HAADVTQAMHCY+ + K+ + +   D ++ LL A  HD+DHPGVNQ FL KTN+YL+  Y+  SVLENHH+R A+ +L ET +  H   +    ++ ++  LI+ATDI+RQNEYL +F T+  ++++ +  A    ++  I+QMALKCADICNPCR W ++  W+  ++ EFF QGD E++  L ++P  D    +   VQ GF+ ++V PLF +W  F  TRLS+ M+  L  N   W   Q + +
Sbjct:  148 ILDEDYCG---QAKCMLEKVGSWNFDIFLFDRLTNGNSLVTLTLYLLSHYGLIELFQLDMVKVHRFLVLVQEDYHNHNPYHNAVHAADVTQAMHCYLKEPKLAKSLTSCDILLGLLAAATHDLDHPGVNQPFLIKTNHYLAVLYRNTSVLENHHWRSAVGLLRETELLSHLPAEDRLTMERQLGSLILATDISRQNEYLSKFRTHLDQEDLCLGNA---SHRHFILQMALKCADICNPCRPWELSKQWSEKVTEEFFHQGDIEKKHKLEVSPLCDSENNSIADVQIGFMTYVVEPLFAEWARFSDTRLSQTMLGHLCLNKASWNAMQPEAS 472
[Close]
BLAST of Phosphodiesterase vs. Ensembl Sea Lamprey
Match: pde7a (phosphodiesterase 7A [Source:ZFIN;Acc:ZDB-GENE-031222-10])

HSP 1 Score: 290.812 bits (743), Expect = 3.494e-96
Identity = 137/319 (42.95%), Postives = 207/319 (64.89%), Query Frame = 3 
Query:  138 LLLKSVRWNYDIFTLDRITSGHPIVHLGMFLFEYHNLLTSFKIDYLKFLHTLTLLENNYHQKNPYHNALHAADVTQAMHCYVSDSKIRQKMKQFDFMVSLLGAMFHDVDHPGVNQAFLEKTNNYLSEFYKAQSVLENHHYRMALSILHETRVFHHFTTKQWGELQYRMYKLIMATDIARQNEYLDQFTNFIEQ-NIGIKEAFTKENKILIMQMALKCADICNPCREWRVAACWANLISAEFFRQGDRERRMNLPLAPTMDRYGITKPKVQTGFIRFLVRPLFNKWNEFMKTRLSEKMVQQLEQNLLRWELKQNQMAEKS 1091
            +L+K+  W++D+F  DR+T+G+ +V L   LF +H L+  F++D +K    L +++ +YH +NPYHNA+HAADVTQAMHCY+ + K+   + + D M+ LL A  HDVDHPGVNQ FL KT+++L+  Y   SVLENHH+R  + +L E+ +F H    +  +++  +  LI+ATDI+RQNE+L QF + +++ ++ ++EA    ++  I+Q+ALKCADICNPCR W  +  W+  +  EFF+QGD ER+  L ++P  DRY  T P +Q GF+ F+V PLF +W  FM       M+  L  N   W   QN++   S
Sbjct:    1 MLMKAASWSFDMFLFDRLTNGNSLVSLTCHLFNFHGLIQHFQLDMVKLRGFLVMVQEDYHNQNPYHNAVHAADVTQAMHCYLREPKLAVHLTRRDIMLGLLAASAHDVDHPGVNQPFLIKTHHHLASLYHNSSVLENHHWRSTVGMLRESGLFAHLPMDERLQMERDLGSLILATDISRQNEFLSQFKSHLDKGDLCLEEA---PHRHFILQIALKCADICNPCRVWDTSKRWSEKVCEEFFKQGDMERKWRLEISPLCDRYTQTVPNIQIGFMTFVVEPLFMEWARFMGYTHLSPMLGHLGLNKASWRGLQNELEAGS 316
[Close]
BLAST of Phosphodiesterase vs. Ensembl Sea Lamprey
Match: pde8a (phosphodiesterase 8A [Source:ZFIN;Acc:ZDB-GENE-070112-622])

HSP 1 Score: 181.8 bits (460), Expect = 2.583e-51
Identity = 93/327 (28.44%), Postives = 167/327 (51.07%), Query Frame = 3 
Query:  159 WNYDIFTLDRITSGHPIVHLGMFLFEYHNLLTSFKIDYLKFLHTLTLLENNYHQKNPYHNALHAADVTQAMHCYVSDSKIRQKMKQFDFMVSLLGAMFHDVDHPGVNQAFLEKTNNYLSEFYKAQSVLENHHYRMALSILHETR---VFHHFTTKQWGELQYRMYKLIMATDIARQNEYLDQFTNFIEQ---------NIGIKEAFTKEN-------------KILIMQMALKCADICNPCREWRVAACWANLISAEFFRQGDRERRMNLPLA-PTMDRYGITKPKVQTGFIRFLVRPLFNKWNEFMKTRLSEKMVQQLEQNLLRWE 1061
            W++DIF L+  T   P+V+LG+ +F    +              L+L+E NYH  N YHN+ HAADV  A   ++   +++  + Q D + +L+ A  HDVDHPG   +FL    + L+  Y   +VLE+HH  +A  +    R   +F +    ++  L+  +  +++AT++ +  E++++F N + +         ++ +  + ++++             ++L+ +M +KCAD+CNPCR   +   WA  IS E+F Q D E+R  LP+  P  DR   + PK Q  FI + +  +F+ W+ + +      ++Q L  N   W+
Sbjct:  343 WDFDIFELESSTHARPLVYLGLKVFARFGVCDFLGCSEATLRAWLSLIEANYHSSNSYHNSTHAADVLHATAYFLRKERVKSCLDQADEVAALIAATVHDVDHPGRTNSFLCNAGSELAVLYNDTAVLESHHAALAFQLSMRDRAANIFRNMDRSEFRTLRQAIIDMVLATEMTKHFEHVNKFVNSVNKMAAAGSTGDSVSLNGSSSEDDSGGGPGPPSTPEMRLLVKRMLIKCADVCNPCRPLALCVEWAGRISEEYFAQTDEEKRKGLPVVMPVFDRCSCSVPKSQISFIDYFITDMFDAWDAYAEL---PNLMQHLSTNYRYWK 666
[Close]
BLAST of Phosphodiesterase vs. Ensembl Sea Lamprey
Match: pde1a (phosphodiesterase 1A, calmodulin-dependent [Source:ZFIN;Acc:ZDB-GENE-090831-2])

HSP 1 Score: 157.532 bits (397), Expect = 3.052e-43
Identity = 87/303 (28.71%), Postives = 155/303 (51.16%), Query Frame = 3 
Query:  156 RWNYDIFTLDRITSGHPIVHLGMFLFEYHNLLTSFKIDYLKFLHTLTLLENNYHQ-KNPYHNALHAADVTQAMHCYVSDSKIRQKMKQFDFMVSLLGAMFHDVDHPGVNQAFLEKTNNYLSEFYKAQSVLENHHYRMALSILHET--RVFHHFTTKQWGELQYRMYKLIMATDIARQNEYLDQFTNFIEQNIGIKEAFTKENKILIMQMALKCADICNPCREWRVAACWANLISAEFFRQGDRERRMNLPLAPTMDRYGITKPKVQTGFIRFLVRPLFNKWNEFMKTRLSEKMVQQLEQNLLR 1055
            +W++D+F L+  +  H +  +   L   + L++ +KI     +  +  LE  Y + KNPYHN  HAADVTQ +H  +  S +   + + + +  +  A  HD++H G    F  +T + ++  Y  ++VLENHH   A  ++ +    +F + +   W EL+  + ++++ATD++   + +    + ++Q   I       +K   M + L   DI +P +EW +   W   +  EFFRQGDRE ++ LP +P  DR      + Q GF+ F+V P F+     + T ++EK+V  L +   R
Sbjct:  152 KWSFDVFVLNEASGEHALKFVMHELLTRYELISRYKIPVAALVSFVEALEAGYSKHKNPYHNLAHAADVTQTVHYLLLQSGLMHWLSELETLAVIFAAAIHDLEHTGTTNNFHIQTRSDVALLYNDRAVLENHHVSAAYRLMQDDDMNIFINLSKDDWRELRALVVEMVLATDMSCHFQQIKTMKSALQQPESI-------DKSKAMSLLLHAGDISHPTKEWPLHQRWTEALMEEFFRQGDREAKLGLPFSPLCDRNSTMVAQSQIGFMDFIVEPTFS-----VLTDMAEKVVVPLAEEAAR 442
[Close]
BLAST of Phosphodiesterase vs. Ensembl Sea Lamprey
Match: PDE1C (phosphodiesterase 1C [Source:HGNC Symbol;Acc:HGNC:8776])

HSP 1 Score: 154.836 bits (390), Expect = 6.387e-43
Identity = 93/304 (30.59%), Postives = 151/304 (49.67%), Query Frame = 3 
Query:  141 LLKSV-RWNYDIFTLDRITSGHPIVHLGMFLFEYHNLLTSFKIDYLKFLHTLTLLENNYHQ-KNPYHNALHAADVTQAMHCYVSDSKIRQKMKQFDFMVSLLGAMFHDVDHPGVNQAFLEKTNNYLSEFYKAQSVLENHHYRMALSILHETR---VFHHFTTKQWGELQYRMYKLIMATDIARQNEYLDQFTNFIEQNIGIKEAFTKENKILIMQMALKCADICNPCREWRVAACWANLISAEFFRQGDRERRMNLPLAPTMDRYGITKPKVQTGFIRFLVRPLFNKWNEFMKTRLSEKMVQQL 1037
            +LK V +W++D+F L   +  H +  +   LF  ++L+  FKI     +  +  LE  Y + KNPYHN++HAADVTQ +H  +  +     + + + +  +  A  HD +H G    F  +T +  +  Y  +SVLENHH   A  ++ E     +  + +   W EL+  + + ++ATD++     L    N ++Q  G++       K   M + L  ADI +P + W +   W   +  EFFRQGD+E  + L  +P  DR     P+ Q GFI ++V P F      + T LSE +V  L
Sbjct:  137 VLKEVDKWSFDVFALHEASGEHALKFIVYELFTRYDLIARFKIPVSSVVSFVEALEAGYSKHKNPYHNSVHAADVTQTVHYLMLKTGTIHWLNELEILSMIFAAAIHDYEHTGTTNNFHIQTRSDSAILYNDRSVLENHHVSAAYRLMQEDEEMNILINLSKDDWRELRALVVETVLATDMSCHFHQLKSIKNLLQQPEGVE-------KPKAMSLMLHTADISHPAKNWNLHRRWTMSLMEEFFRQGDKEAELGLSFSPLCDRNATMVPQSQIGFIDYIVEPTFT-----VLTDLSEFVVAPL 428
[Close]
BLAST of Phosphodiesterase vs. Ensembl Sea Lamprey
Match: ENSPMAT00000007435.1 (pep scaffold:Pmarinus_7.0:GL486982:1709:8825:-1 gene:ENSPMAG00000006710.1 transcript:ENSPMAT00000007435.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 110.923 bits (276), Expect = 6.264e-29
Identity = 57/182 (31.32%), Postives = 95/182 (52.20%), Query Frame = 3 
Query:  417 FDFMVSLLGAMFHDVDHPGVNQAFLEKTNNYLSEFYKAQSVLENHHYRMALSILHETR--VFHHFTTKQWGELQYRMYKLIMATDIARQNEYLDQFTNFIE----QNIGIKEAFTKENKILIMQMALKCADICNPCREWRVAACWANLISAEFFRQGDRERRMNLPLAPTMDRYGITKPKVQ 944
             + + ++  +  HDVDHPGV+  FL  TN+ L+  Y  +SVLENHH  +   +L E    +F + + KQ   L+  +  +++ATD+++    L      +E     + G+       ++I ++Q  + CAD+ NP +   V   W   I  EFFRQGDRER   + ++P  D++  +  K Q
Sbjct:   11 LEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDESVLENHHLAVGFKLLQEENCDIFQNLSKKQRQTLRKMVIDMVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYTDRIQVLQNMVHCADLSNPTKPLDVYRQWTERIMEEFFRQGDRERERGMEISPMCDKHSASVEKSQ 192
[Close]
BLAST of Phosphodiesterase vs. Ensembl Yeast
Match: PDE2 (High-affinity cyclic AMP phosphodiesterase; component of the cAMP-dependent protein kinase signaling system, protects the cell from extracellular cAMP, contains readthrough motif surrounding termination codon [Source:SGD;Acc:S000005887])

HSP 1 Score: 72.7886 bits (177), Expect = 2.430e-14
Identity = 58/197 (29.44%), Postives = 94/197 (47.72%), Query Frame = 3 
Query:  300 LENNYHQKNPYHNALHAADVTQA---MHCYV-SDSKIRQKMKQFDFMVSLLGAMFHDVDHPGVNQAFLEKTNNYLSEFYKAQSVLENHHYRMALSILHETRVFHHFTTKQWGELQYRMYK-------LIMATDIARQNEYLDQFTNFIEQNIGIKEAFTKENKILIMQMALKCADICNPCREWRVAACWANLISAEF 857
            LE++YHQ N +HN  HA DV QA   +  Y+  D+ ++        ++  + A+ HDV HPG N   L    + +++ +K  S+LEN H  +          F    ++ W +L     K        I+ATD+A  ++Y D+          + E   K+  I ++ + +K ADI N  R   ++A WA LI+ EF
Sbjct:  254 LESSYHQVNKFHNFRHAIDVMQATWRLCTYLLKDNPVQT-------LLLCMAAIGHDVGHPGTNNQLLCNCESEVAQNFKNVSILENFHREL----------FQQLLSEHWPQLLSISKKKFDFISEAILATDMALHSQYEDRL---------MHENPMKQ--ITLISLIIKAADISNVTRTLSISARWAYLITLEF 422
[Close]
BLAST of Phosphodiesterase vs. Ensembl Nematostella
Match: EDO46133 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RQM4])

HSP 1 Score: 184.496 bits (467), Expect = 5.429e-53
Identity = 96/325 (29.54%), Postives = 179/325 (55.08%), Query Frame = 3 
Query:  111 FGIDKKRQ---LLLLKSV-RWNYDIFTLDRITSGHPIVHLGMFLFEYHNLLTSFKIDYLKFLHTLTLLENNYHQKNPYHNALHAADVTQAMHCYVSDSKIRQKMKQFDFMVSLLGAMFHDVDHPGVNQAFLEKTNNYLSEFYKAQSVLENHHYRMALSILH--ETRVFHHFTTKQWGELQYRMYKLIMATDIARQNEYLDQFTNFIE------QNIGIKEAFTKENKILIMQMALKCADICNPCREWRVAACWANLISAEFFRQGDRERRMN-LPLAPTMDRYGITKPKVQTGFIRFLVRPLFNKWNEFMKTRLSEKMVQQLEQN 1046
            FG++ + +     +L++V +W++D F L   T+GHP++ +   + +  +LL  FKI    F++ +TL+EN+Y +  P+HN +HAADVTQ  H  +S           + + +++ +  HDVDHPGVN  FL  TN+ ++  Y  +SVLENHH  +A  +L   +  +F + + ++    +  + ++++ATD A+    L      +E         G+       +++ +++  + CAD+ NP +   +   W + +  EFFRQGD+ER ++ + ++P MDR+  +  K Q  FI F+ +PL+  W E ++   ++ ++  +E N
Sbjct:  192 FGVEVQNESELATILENVNKWDFDAFALGEATNGHPMLAVSYTILQARDLLKIFKIKPTTFINYMTLVENHYLKDVPFHNCIHAADVTQTAHVLLSAQAFDNVFTDLEILSAIIASAVHDVDHPGVNNHFLVATNSEMALMYNDESVLENHHLAVAFQLLQHEDCDIFENLSKQERQTARRMIIEMVLATDNAKHMSLLASLKTMVETKKVAGTGSGVLCLENYTDRMQVLKSLVHCADLSNPTKPLPIYRKWVDRLMEEFFRQGDKERDIDGMEISPMMDRHNASIEKSQVVFIDFVAQPLWETWGELVQPD-AQDLLDTIEDN 515
[Close]
BLAST of Phosphodiesterase vs. Ensembl Nematostella
Match: EDO32142 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SVX8])

HSP 1 Score: 179.489 bits (454), Expect = 1.150e-49
Identity = 97/302 (32.12%), Postives = 162/302 (53.64%), Query Frame = 3 
Query:  141 LLKSVRWNYDIFTLDRITSGHPIVHLGMFLFEYHNLLTSFKI--DYLKFLHTLTLLENNYHQKNPYHNALHAADVTQAMHCYVSDSKIRQKMKQFDFMVSLLGAMFHDVDHPGVNQAFLEKTNNYLSEFYKAQSVLENHHYRMALSIL---HETRVFHHFTTKQWGELQYRMYKLIMATDIARQNEYLDQFTNFI---------EQNIGIKEAF-TKENKILIMQMALKCADICNPCREWRVAACWANLISAEFFRQGDRERRMNLPLA-PTMDRYGITKPKVQTGFIRFLVRPLFNKWNEF 998
            ++    W++DI  L++ ++  P+  LG+ +     +     I  DY+K  + L L+E NYH+KN YHN+ HAADV  A   +++  +++  ++  D + SL+ A+ HDVDHPG   +FL    + L+  Y   +VLE+HH  +A  +     ++ +F +   +++  ++  +  ++MAT++ R  E+L +F N I         + N     A  T EN+ LI +M +KCADI NP R   +   WA  I+ E+F Q D E+R  LP+  P  DR     P+ Q  FI + V  L++ W+ F
Sbjct:  517 MVDEADWDFDILKLEKASNHRPLYFLGLKILNRFRVCEKLNISEDYVK--NWLQLIEANYHRKNAYHNSTHAADVLHATAVFLAKERVKAVLEPLDEVASLIAAIVHDVDHPGYTNSFLCNAGSELAILYNDIAVLESHHAALAFKLTARDDKSNIFSNLDVEEFRTVRQAIIDMVMATEMTRHFEHLSKFVNSINKRRSSSTPDSNTSTSTALNTPENRTLIKRMLIKCADIANPARPRYLCKEWAYRIAEEYFSQTDEEKRRGLPVVMPVFDRATCNVPRSQVWFIDYFVSDLYDAWDAF 816
[Close]
BLAST of Phosphodiesterase vs. Ensembl Nematostella
Match: EDO37301 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SGA1])

HSP 1 Score: 159.073 bits (401), Expect = 6.159e-45
Identity = 89/289 (30.80%), Postives = 143/289 (49.48%), Query Frame = 3 
Query:  147 KSVRWNYDIFTLDRITSGHPIVHLGMFLFEYHNLLTSFKIDYLKFLHTLTLLENNYHQ-KNPYHNALHAADVTQAMHCYVSDSKIRQKMKQFDFMVSLLGAMFHDVDHPGVNQAFLEKTNNYLSEFYKAQSVLENHHYRMALSILH--ETRVFHHFTTKQWGELQYRMYKLIMATDIARQNEYLDQFTNFIEQNIGIKEAFTKENKILIMQMALKCADICNPCREWRVAACWANLISAEFFRQGDRERRMNLPLAPTMDRYGITKPKVQTGFIRFLVRPLFNKWNEFMK 1004
            K+  W +D+F L     GHP+ ++G  +    ++L +FKI  +     L  +E  Y +  NPYHN  HAADVT  +H ++    + + +   +    LL A+ HD++H G   AF   + + L+  Y  +SVLENHH   A  IL   E  +      +Q+ +++  M   ++ATD++   E L          + +      EN+  ++Q+ L  ADI NP ++W +   W   I  EFF QGD E  + L ++P  DR     P+ Q GFI F+V P     +E ++
Sbjct:   77 KAFEWTFDVFALSESCEGHPLRYIGYEVLHRRDMLRNFKIHAMTLDRFLQDVETGYKRHSNPYHNDCHAADVTHTVHYFLECMGVSKYLSDLEVFGLLLSAIIHDLEHTGTTNAFHINSRSDLALLYNDRSVLENHHVSCAFRILQDDEKNILSGLNLEQYADVRSLMIDTVLATDMSSHFEQLRLM------KVALVAGSPIENR-EVVQLLLHVADISNPTKDWTIHRQWTTKIMEEFFTQGDMEIELGLDVSPLCDRSTTLIPESQIGFIDFIVSPALEVCSEVLE 358
[Close]
BLAST of Phosphodiesterase vs. Ensembl Nematostella
Match: EDO32179 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SVS5])

HSP 1 Score: 151.369 bits (381), Expect = 6.109e-41
Identity = 85/254 (33.46%), Postives = 140/254 (55.12%), Query Frame = 3 
Query:  243 NLLTSFKIDYLKFLHTLTLLENNYHQKNPYHNALHAADVTQAMHCYVSDSKIRQKMKQFDFMVSLLGAMFHDVDHPGVNQAFLEKTNNYLSEFYKAQSVLENHHYRMALSILHETR--VFHHFTTKQWGELQYRMYKLIMATDIARQNEYLDQFTNFIEQNIGIKEAFTKENKILIMQMALKCADICNPCREWRVAACWANLISAEFFRQGDRERRMNLPLAPTMDRYGITKPKVQTGFIRFLVRPLFNKWNEF 998
             LL  FKI+  K  H L  +  +Y+   P+HN  HA  VTQ M+  +  ++I  K+ + D ++ L  A+ HD+DHPG N A+       L+  Y   S LENHH  +A  I+ + +  +  + + + + +++  M K I++TD+AR ++ L++F   ++      +   + +K ++MQ+ +K +D+ N  R   VA  W + +  EFF Q D E+   LP+AP MDR  +TKP  Q GFI+F++ PLF    E 
Sbjct:  196 GLLDEFKIERSKLQHFLFEVYRHYN-PTPFHNFRHAFCVTQMMYGLIWLTEIFNKITKQDLLIMLTSALCHDLDHPGYNNAYQINARTELALRYNDISPLENHHCAVAFDIMKQDKSNILQNVSAETFKKIREGMIKCILSTDMARHSDILNKFKELLKSGFKFDD---EAHKSMLMQIMIKVSDVSNEARPMDVAEPWLDCLLQEFFIQSDVEKLEGLPVAPFMDRDKVTKPSAQIGFIKFVLVPLFEALGEL 445
[Close]
BLAST of Phosphodiesterase vs. Ensembl Nematostella
Match: EDO43748 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RXZ4])

HSP 1 Score: 121.709 bits (304), Expect = 3.806e-31
Identity = 93/349 (26.65%), Postives = 155/349 (44.41%), Query Frame = 3 
Query:  105 EYFGIDKKRQL--LLLKSVRWNYDIFTLDRITSGHPIVHLGMFLFEYHNLLTSFKIDYLKFLHTLTLLENNYHQKNPYHNALHAADVTQAMHCYVSDSKIR--------QKMKQ-------------------------------FDFMVSLL----------GAMFHDVDHPGVNQAFLEKTNNYLSEFYKAQSVLENHHYRMALSILHETRVFH---HFTTKQWGELQYRMYKLIMATDIARQNEYLDQFTNFIEQNIGIKEAFTKENKILIMQMALKCADICNPCREWRVAACWANLISAEFFRQGDRERRMNLPLAPTMDRYGITKPKVQTGFIRFLVRPLFNKW 989
            E F + +  +L  L+ K   WN+ IF  D    G+ +V +   +F+       FKI   KFL+    LE+ YH   PYHN++HA+DV Q ++ +++ +KI         QK+                                 +  +V ++           A  HD DHPG   AFL  T ++ +  Y  +SVLENHH   A ++L     ++     +  ++   ++   + I+ATD+ R  + L  F     +  G     ++ +++L +Q  +K +DI  P +   +   W   I  EF+ QGD ER   + ++P MDR      ++Q  FI  LV PL+N +
Sbjct:    6 EEFELPRSEELTRLMDKVTDWNFPIF--DACEHGNILVQVSYRIFQNAGFFEIFKIPERKFLNYFFALESGYHSI-PYHNSIHASDVLQGVY-FLTTAKIPGFCPPGTPQKLGDNESDSDSDSGITSGVLGEGEEDKKDDDGGGDYGALVDVIPLLELLSLYTAAAMHDYDHPGRTNAFLVATLSHQALLYNDRSVLENHHAAAAFTLLMSDPKYNFLCELSPAEFKRFRFLAIEAILATDLKRHFDILSDFNAKTAE--GGVNWDSEADRLLTLQFCIKMSDISGPSKRRDIHTLWTERIVEEFYEQGDDERARGMAVSPYMDRQQPHVAQLQDSFINHLVAPLYNSY 348
[Close]
BLAST of Phosphodiesterase vs. Ensembl Medaka
Match: pde7a (phosphodiesterase 7A [Source:NCBI gene;Acc:101157095])

HSP 1 Score: 290.426 bits (742), Expect = 2.182e-93
Identity = 137/354 (38.70%), Postives = 218/354 (61.58%), Query Frame = 3 
Query:   93 VLDSEYFGIDKKRQLLLLKSVRWNYDIFTLDRITSGHPIVHLGMFLFEYHNLLTSFKIDYLKFLHTLTLLENNYHQKNPYHNALHAADVTQAMHCYVSDSKIRQKMKQFDFMVSLLGAMFHDVDHPGVNQAFLEKTNNYLSEFYKAQSVLENHHYRMALSILHETRVFHHFTTKQWGELQYRMYKLIMATDIARQNEYLDQFTNFIE-QNIGIKEAFTKENKILIMQMALKCADICNPCREWRVAACWANLISAEFFRQGDRERRMNLPLAPTMDRYGITKPKVQTGFIRFLVRPLFNKWNEFMKTRLSEKMVQQLEQNLLRWELKQNQMAEKSDMLGEDAKPVSQTIPKTTAA 1151
            +LD +Y G   + Q +L K   WN+DIF  DR+T+G+ +V L   L   + L+  F++D +K    L +++ +YH  NPYHNA+HAADVTQAM+C++ +  + + +  +D ++ LL A  HD+ HPGVNQ FL KT++YL+  Y+  SVLENHH++ A+ +L ETR+F H   +    ++  +  LI+ATDI+RQN+YL +F   ++ +N+ +  A    ++  ++QMALKCADICNPCR W ++  W+  ++ EFF+QGD E++  L ++P  DR   T   +Q GF+ ++V PLF +W  F  +RLS+ M+  +  N   WE  Q +    S+  G  A      +   +++
Sbjct:  141 ILDEDYNG---QAQCMLEKVGNWNFDIFLFDRLTNGNSLVTLTFHLLNKYGLVELFQLDMVKLWRFLVMVQEDYHNDNPYHNAVHAADVTQAMYCFLQEPMLAKSLTSYDILLGLLAAATHDLGHPGVNQPFLIKTDHYLATLYRNTSVLENHHWKSAVGLLRETRLFSHLPAEDSLNMERELGSLILATDISRQNDYLSRFRMHLDKENLCLSNA---SHRHFVLQMALKCADICNPCRPWELSKQWSERVTEEFFQQGDIEKKHKLEVSPLCDREANTIGNIQIGFMSYVVEPLFAEWARFSDSRLSQTMLGHMGLNKASWEGLQQEQTAASEEAGPSATDAENAVAGGSSS 488
[Close]
BLAST of Phosphodiesterase vs. Ensembl Medaka
Match: PDE7B (phosphodiesterase 7B [Source:NCBI gene;Acc:101164940])

HSP 1 Score: 263.462 bits (672), Expect = 1.127e-82
Identity = 129/337 (38.28%), Postives = 206/337 (61.13%), Query Frame = 3 
Query:   54 AGCKPPRRIDIYGVLDSEYFGIDKKRQLLLLKSVRWNYDIFTLDRITSGHPIVHLGMFLFEYHNLLTSFKIDYLKFLHTLTLLENNYHQKNPYHNALHAADVTQAMHCYVSDSKIRQKMKQFDFMVSLLGAMFHDVDHPGVNQAFLEKTNNYLSEFYKAQSVLENHHYRMALSILHETRVFHHFTTKQWGELQYRMYKLIMATDIARQNEYLDQFTNFIE-QNIGIKEAFTKENKILIMQMALKCADICNPCREWRVAACWANLISAEFFRQGDRERRMNLPLAPTMDRYGITKPKVQTGFIRFLVRPLFNKWNEFM-KTRLSEKMVQQLEQNLLRW 1058
             G  P     +Y +LD +Y G   +   +L K   WN+DIF  DR+T+G+ +V L   LF  ++L+  F++D +K      +++ +YH +NPYHNA+HAADVTQA++CY+ + K+  ++   D  + L+ A  HDVDHPGVNQ FL KT ++L+  Y+  SVLE+HH+R  + +L E+ +  H   +    ++ ++  LI+ATDI RQNE+L  F   ++ Q++ + EA    ++  I+Q+ALKCAD+CNPCR W ++  W   +  EF +QG+ E++ +L ++P  D    + P +Q+GFI  +  PLF +WN F   + LS+ M+  L +N   W
Sbjct:  165 GGLAPHDSGSLY-LLDDDYLG---QAAHMLSKVGTWNFDIFLFDRLTNGNSLVTLMCHLFNIYDLIHHFQLDIVKLHRFFGMVQKDYHSQNPYHNAIHAADVTQAIYCYLKEPKLADQLSPLDVFLGLIAAAAHDVDHPGVNQPFLIKTRHHLASLYQNTSVLESHHWRSTVGMLRESGLLAHLPAEITRVIEQQLGSLILATDICRQNEFLLTFREHLDNQDLDLLEA---SHRHFILQIALKCADVCNPCRSWELSRQWGERVCEEFHKQGELEKKFDLEVSPQCDHQVDSVPAIQSGFISCIAEPLFEEWNRFTHPSLLSQTMLDHLHKNKAHW 494
[Close]
BLAST of Phosphodiesterase vs. Ensembl Medaka
Match: pde4ca (cAMP-specific 3',5'-cyclic phosphodiesterase 4C [Source:NCBI gene;Acc:101161266])

HSP 1 Score: 187.193 bits (474), Expect = 1.166e-52
Identity = 99/322 (30.75%), Postives = 170/322 (52.80%), Query Frame = 3 
Query:  111 FGIDKKRQLLLLKSV----RWNYDIFTLDRITSGHPIVHLGMFLFEYHNLLTSFKIDYLKFLHTLTLLENNYHQKNPYHNALHAADVTQAMHCYVSDSKIRQKMKQFDFMVSLLGAMFHDVDHPGVNQAFLEKTNNYLSEFYKAQSVLENHHYRMALSILHETR--VFHHFTTKQWGELQYRMYKLIMATDIARQNEYLDQFTNFIE----QNIGIKEAFTKENKILIMQMALKCADICNPCREWRVAACWANLISAEFFRQGDRERRMNLPLAPTMDRYGITKPKVQTGFIRFLVRPLFNKWNEFMKTRLSEKMVQQLEQN 1046
            FG++  ++ LL K +    RW  DIF +   +   P+      +F+  +LL +FKI    F++ +  LE++YH +  YHN +HAADV Q+MH  +S   +       + + +L  +  HDVDHPGV+  FL  TN+ L+  Y   SVLENHH  +   +L E +  +F   + KQ   L+  +  +++ATD+++    L      +E     ++G+       ++I ++Q  + CAD+ NP +   +   W + I  EFF QGDRER   + ++P  D++  +  K Q GFI ++  PL+  W + +    +++++  LE N
Sbjct:  278 FGVNASQEGLLAKQLEDINRWGIDIFKVAEYSGTRPLTVTMYSIFQERDLLKTFKIPVDIFINFVMTLEDHYHSEVAYHNNIHAADVVQSMHVLLSTPALEAVFTDLEILAALFASAIHDVDHPGVSNQFLINTNSELALMYNDMSVLENHHLAVGFKLLQEDQCDIFQDLSKKQRQSLRKMVIDMVLATDMSKHMNLLADLKTMVETKKVTSLGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLELYRKWTDRIMVEFFTQGDRERDKGMEISPMCDKHNASIEKNQVGFIDYIAHPLWETWADLVHPD-AQEILDTLEDN 598
[Close]
BLAST of Phosphodiesterase vs. Ensembl Medaka
Match: pde4cb (phosphodiesterase 4C [Source:NCBI gene;Acc:101163965])

HSP 1 Score: 187.963 bits (476), Expect = 1.844e-52
Identity = 103/350 (29.43%), Postives = 175/350 (50.00%), Query Frame = 3 
Query:   27 LNMIKTKKRAGCKPPRRIDIYGVLDSEYFGIDKKRQLLLLKSV----RWNYDIFTLDRITSGHPIVHLGMFLFEYHNLLTSFKIDYLKFLHTLTLLENNYHQKNPYHNALHAADVTQAMHCYVSDSKIRQKMKQFDFMVSLLGAMFHDVDHPGVNQAFLEKTNNYLSEFYKAQSVLENHHYRMALSILHETR--VFHHFTTKQWGELQYRMYKLIMATDIARQNEYLDQFTNFIE----QNIGIKEAFTKENKILIMQMALKCADICNPCREWRVAACWANLISAEFFRQGDRERRMNLPLAPTMDRYGITKPKVQTGFIRFLVRPLFNKWNEFMKTRLSEKMVQQLEQN 1046
            ++ +K   ++   PP  I          FG++   + LL K +    RW  DIF +   +   P+  +   +F+  +LL +FKI    F+  +  LE++YH    YHN +HAADV Q+ H  +S   +       + M +L  +  HDVDHPGV   FL  T++ L+  Y   SVLENHH  +   +L E    +F + + KQ   L+  +  +++ATD+++   +L      +E     N+G+       ++I ++Q  + CAD+ NP +   +   W + I  E F QGDRER   + ++P  D+   +  K Q GFI ++V PL+  W + +    +++++  LE N
Sbjct:  271 ISGVKKATQSPSLPPASI--------SRFGVNTPHESLLAKEIEDIDRWGMDIFKIAEYSGNRPLTVIMYSIFQERDLLKTFKIQADTFITFMMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEIMAALFASAIHDVDHPGVTNQFLINTSSELALMYNDASVLENHHLAVGFKLLQEENCDIFENLSKKQKDSLRKMVIDMVLATDMSKHINFLADMKTMVETKKVTNLGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLELYRKWTDRIMVELFTQGDREREKGMEISPMCDKQNASIEKTQVGFIDYVVHPLWETWADLVHPD-AQEILDTLEDN 611
[Close]
BLAST of Phosphodiesterase vs. Ensembl Medaka
Match: pde4cb (phosphodiesterase 4C [Source:NCBI gene;Acc:101163965])

HSP 1 Score: 187.963 bits (476), Expect = 2.014e-52
Identity = 104/353 (29.46%), Postives = 176/353 (49.86%), Query Frame = 3 
Query:   18 FS*LNMIKTKKRAGCKPPRRIDIYGVLDSEYFGIDKKRQLLLLKSV----RWNYDIFTLDRITSGHPIVHLGMFLFEYHNLLTSFKIDYLKFLHTLTLLENNYHQKNPYHNALHAADVTQAMHCYVSDSKIRQKMKQFDFMVSLLGAMFHDVDHPGVNQAFLEKTNNYLSEFYKAQSVLENHHYRMALSILHETR--VFHHFTTKQWGELQYRMYKLIMATDIARQNEYLDQFTNFIE----QNIGIKEAFTKENKILIMQMALKCADICNPCREWRVAACWANLISAEFFRQGDRERRMNLPLAPTMDRYGITKPKVQTGFIRFLVRPLFNKWNEFMKTRLSEKMVQQLEQN 1046
             S ++ +K   ++   PP  I          FG++   + LL K +    RW  DIF +   +   P+  +   +F+  +LL +FKI    F+  +  LE++YH    YHN +HAADV Q+ H  +S   +       + M +L  +  HDVDHPGV   FL  T++ L+  Y   SVLENHH  +   +L E    +F + + KQ   L+  +  +++ATD+++   +L      +E     N+G+       ++I ++Q  + CAD+ NP +   +   W + I  E F QGDRER   + ++P  D+   +  K Q GFI ++V PL+  W + +    +++++  LE N
Sbjct:  286 MSQISGVKKATQSPSLPPASI--------SRFGVNTPHESLLAKEIEDIDRWGMDIFKIAEYSGNRPLTVIMYSIFQERDLLKTFKIQADTFITFMMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEIMAALFASAIHDVDHPGVTNQFLINTSSELALMYNDASVLENHHLAVGFKLLQEENCDIFENLSKKQKDSLRKMVIDMVLATDMSKHINFLADMKTMVETKKVTNLGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLELYRKWTDRIMVELFTQGDREREKGMEISPMCDKQNASIEKTQVGFIDYVVHPLWETWADLVHPD-AQEILDTLEDN 629
[Close]
BLAST of Phosphodiesterase vs. Planmine SMEST
Match: SMESG000053281.1 (SMESG000053281.1)

HSP 1 Score: 790.03 bits (2039), Expect = 0.000e+0
Identity = 374/374 (100.00%), Postives = 374/374 (100.00%), Query Frame = 3 
Query:   33 MIKTKKRAGCKPPRRIDIYGVLDSEYFGIDKKRQLLLLKSVRWNYDIFTLDRITSGHPIVHLGMFLFEYHNLLTSFKIDYLKFLHTLTLLENNYHQKNPYHNALHAADVTQAMHCYVSDSKIRQKMKQFDFMVSLLGAMFHDVDHPGVNQAFLEKTNNYLSEFYKAQSVLENHHYRMALSILHETRVFHHFTTKQWGELQYRMYKLIMATDIARQNEYLDQFTNFIEQNIGIKEAFTKENKILIMQMALKCADICNPCREWRVAACWANLISAEFFRQGDRERRMNLPLAPTMDRYGITKPKVQTGFIRFLVRPLFNKWNEFMKTRLSEKMVQQLEQNLLRWELKQNQMAEKSDMLGEDAKPVSQTIPKTTAAV 1154
            MIKTKKRAGCKPPRRIDIYGVLDSEYFGIDKKRQLLLLKSVRWNYDIFTLDRITSGHPIVHLGMFLFEYHNLLTSFKIDYLKFLHTLTLLENNYHQKNPYHNALHAADVTQAMHCYVSDSKIRQKMKQFDFMVSLLGAMFHDVDHPGVNQAFLEKTNNYLSEFYKAQSVLENHHYRMALSILHETRVFHHFTTKQWGELQYRMYKLIMATDIARQNEYLDQFTNFIEQNIGIKEAFTKENKILIMQMALKCADICNPCREWRVAACWANLISAEFFRQGDRERRMNLPLAPTMDRYGITKPKVQTGFIRFLVRPLFNKWNEFMKTRLSEKMVQQLEQNLLRWELKQNQMAEKSDMLGEDAKPVSQTIPKTTAAV
Sbjct:    1 MIKTKKRAGCKPPRRIDIYGVLDSEYFGIDKKRQLLLLKSVRWNYDIFTLDRITSGHPIVHLGMFLFEYHNLLTSFKIDYLKFLHTLTLLENNYHQKNPYHNALHAADVTQAMHCYVSDSKIRQKMKQFDFMVSLLGAMFHDVDHPGVNQAFLEKTNNYLSEFYKAQSVLENHHYRMALSILHETRVFHHFTTKQWGELQYRMYKLIMATDIARQNEYLDQFTNFIEQNIGIKEAFTKENKILIMQMALKCADICNPCREWRVAACWANLISAEFFRQGDRERRMNLPLAPTMDRYGITKPKVQTGFIRFLVRPLFNKWNEFMKTRLSEKMVQQLEQNLLRWELKQNQMAEKSDMLGEDAKPVSQTIPKTTAAV 374
[Close]
BLAST of Phosphodiesterase vs. Planmine SMEST
Match: SMESG000053281.1 (SMESG000053281.1)

HSP 1 Score: 740.339 bits (1910), Expect = 0.000e+0
Identity = 356/376 (94.68%), Postives = 359/376 (95.48%), Query Frame = 3 
Query:   33 MIKTKKRAGCKPPRRIDIYGVLDSEYFGIDKKRQLLLLKSVRWNYDIFTLDRITSGHPIVHLGMFLFEYHNLLTSFKIDYLKFLHTLTLLENNYHQKNPYHNALHAADVTQAMHCYVSDSKIRQKMKQFDFMVSLLGAMFHDVDHPGVNQAFLEKTNNYLSEFYKAQSVLENHHYRMALSILHETRVFHHFTTKQWGELQYRM--YKLIMATDIARQNEYLDQFTNFIEQNIGIKEAFTKENKILIMQMALKCADICNPCREWRVAACWANLISAEFFRQGDRERRMNLPLAPTMDRYGITKPKVQTGFIRFLVRPLFNKWNEFMKTRLSEKMVQQLEQNLLRWELKQNQMAEKSDMLGEDAKPVSQTIPKTTAAV 1154
            MIKTKKRAGCKPPRRIDIYGVLDSEYFGIDKKRQLLLLKSVRWNYDIFTLDRITSGHPIVHLGMFLFEYHNLLTSFKIDYLKFLHTLTLLENNYHQKNPYHNALHAADVTQAMHCYVSDSKIRQKMKQFDFMVSLLGAMFHDVDHPGVNQAFLEKTNNYLSEFYKAQSVLENHHYRMALSILHETRVFHHFTTKQWGELQYR+  Y L +   I          +NFIEQNIGIKEAFTKENKILIMQMALKCADICNPCREWRVAACWANLISAEFFRQGDRERRMNLPLAPTMDRYGITKPKVQTGFIRFLVRPLFNKWNEFMKTRLSEKMVQQLEQNLLRWELKQNQMAEKSDMLGEDAKPVSQTIPKTTAAV
Sbjct:    1 MIKTKKRAGCKPPRRIDIYGVLDSEYFGIDKKRQLLLLKSVRWNYDIFTLDRITSGHPIVHLGMFLFEYHNLLTSFKIDYLKFLHTLTLLENNYHQKNPYHNALHAADVTQAMHCYVSDSKIRQKMKQFDFMVSLLGAMFHDVDHPGVNQAFLEKTNNYLSEFYKAQSVLENHHYRMALSILHETRVFHHFTTKQWGELQYRIPVYNLNVGKKI----------SNFIEQNIGIKEAFTKENKILIMQMALKCADICNPCREWRVAACWANLISAEFFRQGDRERRMNLPLAPTMDRYGITKPKVQTGFIRFLVRPLFNKWNEFMKTRLSEKMVQQLEQNLLRWELKQNQMAEKSDMLGEDAKPVSQTIPKTTAAV 366
[Close]
BLAST of Phosphodiesterase vs. Planmine SMEST
Match: SMESG000028250.1 (SMESG000028250.1)

HSP 1 Score: 308.916 bits (790), Expect = 2.708e-99
Identity = 142/310 (45.81%), Postives = 206/310 (66.45%), Query Frame = 3 
Query:  138 LLLKSV-RWNYDIFTLDRITSGHPIVHLGMFLFEYHNLLTSFKIDYLKFLHTLTLLENNYHQKNPYHNALHAADVTQAMHCYVSDSKIRQKMKQFDFMVSLLGAMFHDVDHPGVNQAFLEKTNNYLSEFYKAQSVLENHHYRMALSILHETRVFHHFTTKQWGELQYRMYKLIMATDIARQNEYLDQFTN-FIEQNIGIKEAFTKENKILIMQMALKCADICNPCREWRVAACWANLISAEFFRQGDRERRMNLPLAPTMDRYGITKPKVQTGFIRFLVRPLFNKWNEFMKTRLSEKMVQQLEQNLLRWE 1061
            ++L S+  W+++IF L+R TSG P+ +L + LFE HNL+  F++D       L  +E +YHQ NPYHNALHAADVTQA++C + D +I  ++   D + SLL  + HDVDHPG+N  FL  +N++LS  YK QSVLENHH+  +LS+L +T +F HF    W ++      LI ATDI++QN YL  F    + ++  I E   +E KIL++QMA+KCADICNPCR W +  CWA L++ EFF+QGD+E+ + LP++P MDR    +  VQ  FI+FLV PLF  W++F+++ LS  ++  ++ N   W+
Sbjct:   91 MILNSIDNWDFNIFALERFTSGTPLTYLSIHLFEKHNLIQHFQLDISMVFQFLVTIERSYHQSNPYHNALHAADVTQAINCIIQDKQIFGQLTSQDILCSLLSTICHDVDHPGLNNMFLINSNHHLSILYKKQSVLENHHWAFSLSVLRQTNLFLHFDKDLWKQVTNTCGSLIRATDISKQNAYLSDFNKILLSKDSPINEPLNEEQKILVLQMAIKCADICNPCRRWDICNCWAYLVTEEFFQQGDKEKALLLPISPIMDREKSKQAVVQRDFIKFLVLPLFTVWHQFIESNLSRNILDLIDSNKNMWQ 400
[Close]
BLAST of Phosphodiesterase vs. Planmine SMEST
Match: SMESG000028250.1 (SMESG000028250.1)

HSP 1 Score: 309.301 bits (791), Expect = 3.308e-99
Identity = 142/310 (45.81%), Postives = 206/310 (66.45%), Query Frame = 3 
Query:  138 LLLKSV-RWNYDIFTLDRITSGHPIVHLGMFLFEYHNLLTSFKIDYLKFLHTLTLLENNYHQKNPYHNALHAADVTQAMHCYVSDSKIRQKMKQFDFMVSLLGAMFHDVDHPGVNQAFLEKTNNYLSEFYKAQSVLENHHYRMALSILHETRVFHHFTTKQWGELQYRMYKLIMATDIARQNEYLDQFTN-FIEQNIGIKEAFTKENKILIMQMALKCADICNPCREWRVAACWANLISAEFFRQGDRERRMNLPLAPTMDRYGITKPKVQTGFIRFLVRPLFNKWNEFMKTRLSEKMVQQLEQNLLRWE 1061
            ++L S+  W+++IF L+R TSG P+ +L + LFE HNL+  F++D       L  +E +YHQ NPYHNALHAADVTQA++C + D +I  ++   D + SLL  + HDVDHPG+N  FL  +N++LS  YK QSVLENHH+  +LS+L +T +F HF    W ++      LI ATDI++QN YL  F    + ++  I E   +E KIL++QMA+KCADICNPCR W +  CWA L++ EFF+QGD+E+ + LP++P MDR    +  VQ  FI+FLV PLF  W++F+++ LS  ++  ++ N   W+
Sbjct:   91 MILNSIDNWDFNIFALERFTSGTPLTYLSIHLFEKHNLIQHFQLDISMVFQFLVTIERSYHQSNPYHNALHAADVTQAINCIIQDKQIFGQLTSQDILCSLLSTICHDVDHPGLNNMFLINSNHHLSILYKKQSVLENHHWAFSLSVLRQTNLFLHFDKDLWKQVTNTCGSLIRATDISKQNAYLSDFNKILLSKDSPINEPLNEEQKILVLQMAIKCADICNPCRRWDICNCWAYLVTEEFFQQGDKEKALLLPISPIMDREKSKQAVVQRDFIKFLVLPLFTVWHQFIESNLSRNILDLIDSNKNMWQ 400
[Close]
BLAST of Phosphodiesterase vs. Planmine SMEST
Match: SMESG000028250.1 (SMESG000028250.1)

HSP 1 Score: 308.916 bits (790), Expect = 3.406e-99
Identity = 142/310 (45.81%), Postives = 206/310 (66.45%), Query Frame = 3 
Query:  138 LLLKSV-RWNYDIFTLDRITSGHPIVHLGMFLFEYHNLLTSFKIDYLKFLHTLTLLENNYHQKNPYHNALHAADVTQAMHCYVSDSKIRQKMKQFDFMVSLLGAMFHDVDHPGVNQAFLEKTNNYLSEFYKAQSVLENHHYRMALSILHETRVFHHFTTKQWGELQYRMYKLIMATDIARQNEYLDQFTN-FIEQNIGIKEAFTKENKILIMQMALKCADICNPCREWRVAACWANLISAEFFRQGDRERRMNLPLAPTMDRYGITKPKVQTGFIRFLVRPLFNKWNEFMKTRLSEKMVQQLEQNLLRWE 1061
            ++L S+  W+++IF L+R TSG P+ +L + LFE HNL+  F++D       L  +E +YHQ NPYHNALHAADVTQA++C + D +I  ++   D + SLL  + HDVDHPG+N  FL  +N++LS  YK QSVLENHH+  +LS+L +T +F HF    W ++      LI ATDI++QN YL  F    + ++  I E   +E KIL++QMA+KCADICNPCR W +  CWA L++ EFF+QGD+E+ + LP++P MDR    +  VQ  FI+FLV PLF  W++F+++ LS  ++  ++ N   W+
Sbjct:  100 MILNSIDNWDFNIFALERFTSGTPLTYLSIHLFEKHNLIQHFQLDISMVFQFLVTIERSYHQSNPYHNALHAADVTQAINCIIQDKQIFGQLTSQDILCSLLSTICHDVDHPGLNNMFLINSNHHLSILYKKQSVLENHHWAFSLSVLRQTNLFLHFDKDLWKQVTNTCGSLIRATDISKQNAYLSDFNKILLSKDSPINEPLNEEQKILVLQMAIKCADICNPCRRWDICNCWAYLVTEEFFQQGDKEKALLLPISPIMDREKSKQAVVQRDFIKFLVLPLFTVWHQFIESNLSRNILDLIDSNKNMWQ 409
The following BLAST results are available for this feature:
BLAST of Phosphodiesterase vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
PDE7A7.112e-9842.51phosphodiesterase 7A [Source:HGNC Symbol;Acc:HGNC:... [more]
PDE7A1.692e-9742.51phosphodiesterase 7A [Source:HGNC Symbol;Acc:HGNC:... [more]
PDE7B6.434e-8838.97phosphodiesterase 7B [Source:HGNC Symbol;Acc:HGNC:... [more]
PDE7B5.178e-8739.36phosphodiesterase 7B [Source:HGNC Symbol;Acc:HGNC:... [more]
PDE7A1.330e-8443.30phosphodiesterase 7A [Source:HGNC Symbol;Acc:HGNC:... [more]
back to top
BLAST of Phosphodiesterase vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
pde-69.817e-4533.65Probable 3',5'-cyclic phosphodiesterase pde-6 [So... [more]
pde-44.156e-4428.75Probable 3',5'-cyclic phosphodiesterase pde-4 [So... [more]
pde-48.183e-4429.19Probable 3',5'-cyclic phosphodiesterase pde-4 [So... [more]
pde-41.157e-4329.19Probable 3',5'-cyclic phosphodiesterase pde-4 [So... [more]
pde-41.329e-4329.19Probable 3',5'-cyclic phosphodiesterase pde-4 [So... [more]
back to top
BLAST of Phosphodiesterase vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
dnc1.251e-4829.50gene:FBgn0000479 transcript:FBtr0070522[more]
dnc1.006e-4729.50gene:FBgn0000479 transcript:FBtr0070518[more]
dnc1.006e-4729.50gene:FBgn0000479 transcript:FBtr0333312[more]
dnc1.008e-4729.50gene:FBgn0000479 transcript:FBtr0070521[more]
Pde82.153e-4730.79gene:FBgn0266377 transcript:FBtr0344176[more]
back to top
BLAST of Phosphodiesterase vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
pde7a6.284e-9942.21phosphodiesterase 7A [Source:ZFIN;Acc:ZDB-GENE-031... [more]
pde4ca9.153e-5530.50phosphodiesterase 4C, cAMP-specific a [Source:ZFIN... [more]
pde4ca9.153e-5530.50phosphodiesterase 4C, cAMP-specific a [Source:ZFIN... [more]
pde4ca1.690e-5430.79phosphodiesterase 4C, cAMP-specific a [Source:ZFIN... [more]
pde4ba1.639e-5231.37phosphodiesterase 4B, cAMP-specific a [Source:ZFIN... [more]
back to top
BLAST of Phosphodiesterase vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
PDE7A5.696e-9741.84phosphodiesterase 7A [Source:NCBI gene;Acc:1004985... [more]
PDE7A7.180e-9741.84phosphodiesterase 7A [Source:NCBI gene;Acc:1004985... [more]
PDE7A1.816e-9641.84phosphodiesterase 7A [Source:NCBI gene;Acc:1004985... [more]
PDE7A2.327e-9642.86phosphodiesterase 7A [Source:NCBI gene;Acc:1004985... [more]
PDE7A1.169e-9541.67phosphodiesterase 7A [Source:NCBI gene;Acc:1004985... [more]
back to top
BLAST of Phosphodiesterase vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Pde7a1.849e-9843.11phosphodiesterase 7A [Source:MGI Symbol;Acc:MGI:12... [more]
Pde7a4.128e-9843.11phosphodiesterase 7A [Source:MGI Symbol;Acc:MGI:12... [more]
Pde7b4.479e-9039.39phosphodiesterase 7B [Source:MGI Symbol;Acc:MGI:13... [more]
Pde7b4.915e-9039.39phosphodiesterase 7B [Source:MGI Symbol;Acc:MGI:13... [more]
Pde7b2.784e-8939.39phosphodiesterase 7B [Source:MGI Symbol;Acc:MGI:13... [more]
back to top
BLAST of Phosphodiesterase vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|P70453|PDE7A_MOUSE1.293e-9743.11High affinity cAMP-specific 3',5'-cyclic phosphodi... [more]
sp|Q13946|PDE7A_HUMAN8.127e-9742.51High affinity cAMP-specific 3',5'-cyclic phosphodi... [more]
sp|O08593|PDE7A_RAT1.303e-9642.81High affinity cAMP-specific 3',5'-cyclic phosphodi... [more]
sp|Q9QXQ1|PDE7B_MOUSE3.133e-8939.39cAMP-specific 3',5'-cyclic phosphodiesterase 7B OS... [more]
sp|Q9NP56|PDE7B_HUMAN3.090e-8738.97cAMP-specific 3',5'-cyclic phosphodiesterase 7B OS... [more]
back to top
BLAST of Phosphodiesterase vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A4E0RI829.669e-10246.86High affinity cAMP-specific 3' 5'-cyclic phosphodi... [more]
A0A504YUZ93.119e-10146.86Phosphodiesterase OS=Fasciola gigantica OX=46835 G... [more]
A0A068WL131.107e-10044.44High affinity cAMP specific 3'5' cyclic OS=Echinoc... [more]
A0A5K3F0I61.558e-9942.86Uncharacterized protein OS=Mesocestoides corti OX=... [more]
A0A068Y1T07.283e-9944.58High affinity cAMP specific 3'5' cyclic OS=Echinoc... [more]
back to top
BLAST of Phosphodiesterase vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
pde7a5.624e-9542.30phosphodiesterase 7A [Source:NCBI gene;Acc:1030424... [more]
pde7a9.801e-9542.30phosphodiesterase 7A [Source:NCBI gene;Acc:1030424... [more]
pde7a2.092e-9442.30phosphodiesterase 7A [Source:NCBI gene;Acc:1030424... [more]
pde7a3.575e-9442.30phosphodiesterase 7A [Source:NCBI gene;Acc:1030424... [more]
pde7a5.531e-9442.30phosphodiesterase 7A [Source:NCBI gene;Acc:1030424... [more]
back to top
BLAST of Phosphodiesterase vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5
Match NameE-valueIdentityDescription
pde7a3.494e-9642.95phosphodiesterase 7A [Source:ZFIN;Acc:ZDB-GENE-031... [more]
pde8a2.583e-5128.44phosphodiesterase 8A [Source:ZFIN;Acc:ZDB-GENE-070... [more]
pde1a3.052e-4328.71phosphodiesterase 1A, calmodulin-dependent [Source... [more]
PDE1C6.387e-4330.59phosphodiesterase 1C [Source:HGNC Symbol;Acc:HGNC:... [more]
ENSPMAT00000007435.16.264e-2931.32pep scaffold:Pmarinus_7.0:GL486982:1709:8825:-1 ge... [more]
back to top
BLAST of Phosphodiesterase vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 1
Match NameE-valueIdentityDescription
PDE22.430e-1429.44High-affinity cyclic AMP phosphodiesterase; compon... [more]
back to top
BLAST of Phosphodiesterase vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO461335.429e-5329.54Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO321421.150e-4932.12Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO373016.159e-4530.80Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO321796.109e-4133.46Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO437483.806e-3126.65Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
back to top
BLAST of Phosphodiesterase vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
pde7a2.182e-9338.70phosphodiesterase 7A [Source:NCBI gene;Acc:1011570... [more]
PDE7B1.127e-8238.28phosphodiesterase 7B [Source:NCBI gene;Acc:1011649... [more]
pde4ca1.166e-5230.75cAMP-specific 3',5'-cyclic phosphodiesterase 4C [S... [more]
pde4cb1.844e-5229.43phosphodiesterase 4C [Source:NCBI gene;Acc:1011639... [more]
pde4cb2.014e-5229.46phosphodiesterase 4C [Source:NCBI gene;Acc:1011639... [more]
back to top
BLAST of Phosphodiesterase vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000053281.10.000e+0100.00SMESG000053281.1[more]
SMESG000053281.10.000e+094.68SMESG000053281.1[more]
SMESG000028250.12.708e-9945.81SMESG000028250.1[more]
SMESG000028250.13.308e-9945.81SMESG000028250.1[more]
SMESG000028250.13.406e-9945.81SMESG000028250.1[more]
back to top
Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30027985 ID=SMED30027985|Name=Phosphodiesterase|organism=Schmidtea mediterranea sexual|type=transcript|length=1248bp
TCTAAAAATTTATTTCATTTAGTTAATTGAATATGATTAAAACTAAAAAA
AGAGCTGGGTGTAAACCCCCAAGACGAATCGATATTTATGGCGTGTTAGA
TAGTGAATACTTTGGAATTGACAAGAAACGACAACTTTTGCTACTAAAAT
CTGTTAGATGGAATTATGATATTTTTACACTTGATCGGATAACTTCAGGC
CATCCTATTGTTCACTTAGGAATGTTTTTATTCGAATATCATAATTTACT
CACATCCTTTAAAATTGATTATCTGAAATTTCTTCACACATTAACTTTAT
TGGAAAATAATTATCATCAGAAAAATCCCTATCACAATGCACTTCACGCA
GCAGACGTAACTCAAGCTATGCACTGCTATGTATCGGATAGTAAAATCAG
ACAGAAAATGAAGCAGTTTGATTTCATGGTTTCATTATTAGGTGCAATGT
TTCATGATGTTGATCATCCTGGAGTTAATCAAGCATTCCTAGAGAAAACT
AATAATTATTTATCCGAATTTTATAAGGCACAATCTGTCTTAGAGAATCA
TCATTATCGGATGGCACTTTCGATTCTTCACGAAACACGAGTTTTTCATC
ATTTTACAACAAAGCAATGGGGTGAGCTTCAATATCGAATGTACAAATTA
ATAATGGCCACTGACATTGCTAGACAAAATGAATACCTAGACCAGTTTAC
AAATTTTATTGAACAAAATATTGGTATTAAAGAAGCATTTACAAAGGAAA
ATAAAATTCTCATAATGCAGATGGCTCTAAAATGCGCCGATATTTGCAAT
CCTTGCCGAGAATGGCGAGTTGCAGCTTGTTGGGCTAATTTAATATCCGC
TGAGTTTTTCAGACAAGGAGATAGGGAACGGCGAATGAATTTACCACTAG
CTCCAACAATGGATAGGTATGGGATTACAAAGCCCAAAGTTCAAACAGGA
TTTATTCGTTTTCTTGTCCGCCCGTTATTTAACAAATGGAATGAATTCAT
GAAAACAAGATTATCGGAAAAAATGGTGCAACAACTTGAACAGAATCTTT
TGCGTTGGGAGTTAAAGCAAAACCAAATGGCAGAAAAATCTGATATGCTA
GGTGAAGACGCTAAACCAGTATCTCAAACGATTCCAAAAACTACGGCCGC
TGTTTAATTTCTTTTCTTTTTTGAATTTTTGATTTGGTTTTTCCTTATCG
AATGAATAATTTTTAGTTTTCTATTTACAATCATAGCATTTAGGTCAG
back to top

protein sequence of SMED30027985-orf-1

>SMED30027985-orf-1 ID=SMED30027985-orf-1|Name=SMED30027985-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=375bp
MIKTKKRAGCKPPRRIDIYGVLDSEYFGIDKKRQLLLLKSVRWNYDIFTL
DRITSGHPIVHLGMFLFEYHNLLTSFKIDYLKFLHTLTLLENNYHQKNPY
HNALHAADVTQAMHCYVSDSKIRQKMKQFDFMVSLLGAMFHDVDHPGVNQ
AFLEKTNNYLSEFYKAQSVLENHHYRMALSILHETRVFHHFTTKQWGELQ
YRMYKLIMATDIARQNEYLDQFTNFIEQNIGIKEAFTKENKILIMQMALK
CADICNPCREWRVAACWANLISAEFFRQGDRERRMNLPLAPTMDRYGITK
PKVQTGFIRFLVRPLFNKWNEFMKTRLSEKMVQQLEQNLLRWELKQNQMA
EKSDMLGEDAKPVSQTIPKTTAAV*
back to top
Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000208testis
PLANA:0000220spermatogonium
PLANA:0000221spermatocyte
PLANA:0000222spermatid
PLANA:0000232copulatory apparatus
PLANA:0002089reproductive organ
PLANA:0002109X1 cell
PLANA:0003304testis primordium
Vocabulary: INTERPRO
TermDefinition
IPR036971PDEase_catalytic_dom_sf
IPR023088PDEase
IPR003607HD/PDEase_dom
IPR002073PDEase_catalytic_dom
IPR023174PDEase_CS
Vocabulary: molecular function
TermDefinition
GO:0008081phosphoric diester hydrolase activity
GO:00041143',5'-cyclic-nucleotide phosphodiesterase activity
GO:00041153',5'-cyclic-AMP phosphodiesterase activity
GO:0016787hydrolase activity
GO:0046872metal ion binding
Vocabulary: biological process
TermDefinition
GO:0007165signal transduction
GO:0006198cAMP catabolic process
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
NoneNo IPR availableCOILSCoilCoilcoord: 332..352
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 353..374
NoneNo IPR availablePANTHERPTHR11347:SF203coord: 20..351
NoneNo IPR availablePANTHERPTHR11347CYCLIC NUCLEOTIDE PHOSPHODIESTERASEcoord: 20..351
NoneNo IPR availableSUPERFAMILYSSF109604HD-domain/PDEase-likecoord: 42..352
IPR0230883'5'-cyclic nucleotide phosphodiesterasePRINTSPR00387PDIESTERASE1coord: 96..109
score: 54.71
coord: 141..156
score: 48.38
coord: 168..184
score: 45.53
coord: 249..262
score: 26.57
coord: 266..282
score: 55.41
IPR003607HD/PDEase domainSMARTSM00471hd_13coord: 98..267
e-value: 1.0E-6
score: 38.3
IPR003607HD/PDEase domainCDDcd00077HDccoord: 100..276
e-value: 1.35748E-6
score: 45.4081
IPR0369713'5'-cyclic nucleotide phosphodiesterase, catalytic domain superfamilyGENE3DG3DSA:1.10.1300.10coord: 21..346
e-value: 6.6E-105
score: 352.8
IPR0020733'5'-cyclic nucleotide phosphodiesterase, catalytic domainPFAMPF00233PDEase_Icoord: 100..335
e-value: 7.7E-70
score: 235.3
IPR0020733'5'-cyclic nucleotide phosphodiesterase, catalytic domainPROSITEPS51845PDEASE_I_2coord: 14..349
score: 85.652
IPR0231743'5'-cyclic nucleotide phosphodiesterase, conserved sitePROSITEPS00126PDEASE_I_1coord: 141..152