Glypican-1

Overview
NameGlypican-1
Smed IDSMED30027983
Length (bp)3385
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Glypican-1 (SMED30027983) t-SNE clustered cells

Violin plots show distribution of expression levels for Glypican-1 (SMED30027983) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Glypican-1 (SMED30027983) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Glypican-1 (SMED30027983) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30027983

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 7

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
nervous systemSMED30027983SMESG000032627.1 SMESG000033244.1 dd_Smed_v4_4078_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
neoblastSMED30027983SMESG000032627.1 SMESG000033244.1 dd_Smed_v4_4078_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymal cellSMED30027983SMESG000032627.1 SMESG000033244.1 dd_Smed_v4_4078_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
muscle cellSMED30027983SMESG000032627.1 SMESG000033244.1 dd_Smed_v4_4078_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30027983SMESG000032627.1 Contig37032uc_Smed_v2PMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30027983SMESG000032627.1 Contig37032newmark_estsPMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
epidermisSMED30027983SMESG000032627.1 SMESG000033244.1 dd_Smed_v4_4078_0_1dd_Smed_v4PMID:28292427
Wurtzel et al., 2017		whole organism asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Glypican-1 vs. Ensembl Human
Match: GPC6 (glypican 6 [Source:HGNC Symbol;Acc:HGNC:4454])

HSP 1 Score: 121.709 bits (304), Expect = 5.977e-28
Identity = 93/395 (23.54%), Postives = 168/395 (42.53%), Query Frame = 2 
Query:  245 CPILQTRNCCNSVILKEMSSVSEIKLKGFAEEKLENLLTMFSNDSYILMNMYLNDLENTKNDLNQLFSATYGYNYKVEKNFFFSWFDKLKMYMEGKKHNIGQLLDEFFLEMAGKIVKILIPP-ESSPEVTKCQIDRLIEAKPYQEADNSLKKNIIRSYAPSRMFVNAIAVGRDGFRALMNKITPSSNCVAQFNTQFHCMLCNGL-TVKTCPVSCKSVMENCFGSFKLAELKKLDKIFTKYLSALFELANKLDNQLNFPAVNHKMNVQISTAIMNIQNIYPTIKEQIKAKCQN--TGSKVRRKRQVAKEFVAWQTKLGDESPFWKKKLNDNLKSGVSKKTPVGSQNTKLNDFLSPMSRRIKTKYKALEGYFLRGVHDFCTLNSQSNESSSTQCWNG 1417
            CP  Q   CC + +  ++S  S+++ +   EE    + T F +        +   LEN +  LN +F  TYG  Y      F   F +LK Y  G   N+ ++L++F+  +  ++ +++ P    S +  +C      + KP+ +    LK  + R++  +R FV  + VGR+     ++K++P+  C+       +C  C GL TV+ C   C +VM+ C     LA    LD  +  ++ A+  +A +L+   N  +V   ++V+IS AIMN+Q     +  ++   C        +R  R   + F                  N   +    ++ P  +  T L+  ++ +  ++K   K           D       SNE    +CWNG
Sbjct:   60 CP--QEYTCCTTEMEDKLSQQSKLEFENLVEETSHFVRTTFVSRHKKFDEFFRELLENAEKSLNDMFVRTYGMLYMQNSEVFQDLFTELKRYYTGGNVNLEEMLNDFWARLLERMFQLINPQYHFSEDYLECVSKYTDQLKPFGDVPRKLKIQVTRAFIAARTFVQGLTVGRE-VANRVSKVSPTPGCIRALMKMLYCPYCRGLPTVRPCNNYCLNVMKGC-----LANQADLDTEWNLFIDAMLLVAERLEGPFNIESVMDPIDVKISEAIMNMQENSMQVSAKVFQGCGQPKPAPALRSARSAPENF------------------NTRFRPYNPEERPTTAAGTSLDRLVTDIKEKLKLSKKVWSALPYTICKDESVTAGTSNEE---ECWNG 425
[Close]
BLAST of Glypican-1 vs. Ensembl Human
Match: GPC4 (glypican 4 [Source:HGNC Symbol;Acc:HGNC:4452])

HSP 1 Score: 104.76 bits (260), Expect = 2.033e-22
Identity = 72/290 (24.83%), Postives = 135/290 (46.55%), Query Frame = 2 
Query:  245 CPILQTRNCCNSVILKEMSSVSEIKLKGFAEEKLENLLTMFSNDSYILMNMYLNDLENTKNDLNQLFSATYGYNYKVEKNFFFSWFDKLKMYMEGKKHNIGQLLDEFFLEMAGKIVKILIPP-ESSPEVTKCQIDRLIEAKPYQEADNSLKKNIIRSYAPSRMFVNAIAVGRDGFRALMNKITPSSNCVAQFNTQFHCMLCNGL-TVKTCPVSCKSVMENCFGSFKLAELKKLDKIFTKYLSALFELANKLDNQLNFPAVNHKMNVQISTAIMNIQNIYPTIKEQIKAKC 1108
            CP  Q   CC+  + ++ S  S+   K    E+  +L  +F++        +   LEN +  LN +F  TYG+ Y      F   F +LK Y      N+ ++L++F+  +  ++ +++      + E  +C      + KP+ +    LK  + R++  +R F   +AV  D   + ++ + P++ C        +C  C GL TVK C   C ++M  C     LA    LD  +  ++ A+  +A +L+   N  +V   ++V+IS AIMN+Q+    + +++   C
Sbjct:   60 CP--QGSTCCSQEMEEKYSLQSKDDFKSVVSEQCNHLQAVFASRYKKFDEFFKELLENAEKSLNDMFVKTYGHLYMQNSELFKDLFVELKRYYVVGNVNLEEMLNDFWARLLERMFRLVNSQYHFTDEYLECVSKYTEQLKPFGDVPRKLKLQVTRAFVAARTFAQGLAVAGD-VVSKVSVVNPTAQCTHALLKMIYCSHCRGLVTVKPCYNYCSNIMRGC-----LANQGDLDFEWNNFIDAMLMVAERLEGPFNIESVMDPIDVKISDAIMNMQDNSVQVSQKVFQGC 341
[Close]
BLAST of Glypican-1 vs. Ensembl Human
Match: GPC2 (glypican 2 [Source:HGNC Symbol;Acc:HGNC:4450])

HSP 1 Score: 94.7449 bits (234), Expect = 2.682e-19
Identity = 85/410 (20.73%), Postives = 159/410 (38.78%), Query Frame = 2 
Query:  245 CPILQTRNCCNSVILKEMSSVSEIKLKGFAEEKLENLLTMFSNDSYILMNMYLNDLENTKNDLNQLFSATYGYNYKVEKNFFFSWFDKLKMYMEGKKHNIGQLLDEFFLEMAGKIVKILIPPESSPEVTKCQIDRLIEA-----KPYQEADNSLKKNIIRSYAPSRMFVNAIAVGRDGFRALMNKITPSSNCVAQFNTQFHCMLCNGL-TVKTCPVSCKSVMENCFGSFKLAELKKLDKIFTKYLSALFELANKLDNQLNFPAVNHKMNVQISTAIMNIQNIYPTIKEQIKAKCQNTGSKVRRKRQVAKEFVAWQTKLGDESPFWKKKLNDNLKSGVSKKTPVGSQNTKLNDFLSPMSRRIKTKYKALEGYFLRGVHDFCTLNSQSNESS--STQCWNGT-----LPGIV 1435
            CP  Q   CC+S   + +   +E   +G  E+    L+   +         +L  L   ++ L QLFS +YG  Y      F   F +L+ +       +   L +F+ ++  ++  +L P  S P      + RL  +     +P+ ++   L+  I R+   +R FV  +  GR+     + K+  S  C         C LC G+ ++  C   C +V+  C  S      + L+  +  YL  L  LA+KL    +F      + V+IS  +M +Q     +  Q+  +C        R R+               +P  +++          ++ P  +  T L+  +  +  R+      + G++ R     C  +  + ++S  +  CW G      LP +V
Sbjct:   62 CP--QEYTCCSSETEQRLIRETEATFRGLVEDSGSFLVHTLAARHRKFDEFFLEMLSVAQHSLTQLFSHSYGRLYAQHALIFNGLFSRLRDFYGESGEGLDDTLADFWAQLLERVFPLLHPQYSFPPDYLLCLSRLASSTDGSLQPFGDSPRRLRLQITRTLVAARAFVQGLETGRNVVSEAL-KVPVSEGCSQALMRLIGCPLCRGVPSLMPCQGFCLNVVRGCLSS------RGLEPDWGNYLDGLLILADKLQGPFSFELTAESIGVKISEGLMYLQENSAKVSAQVFQECGPPDPVPARNRR---------------APPPREEAGRLWSMVTEEERPTTAAGTNLHRLVWELRERLAR----MRGFWARLSLTVCGDSRMAADASLEAAPCWTGAGRGRYLPPVV 443
[Close]
BLAST of Glypican-1 vs. Ensembl Human
Match: GPC1 (glypican 1 [Source:HGNC Symbol;Acc:HGNC:4449])

HSP 1 Score: 79.7221 bits (195), Expect = 1.464e-14
Identity = 64/308 (20.78%), Postives = 129/308 (41.88%), Query Frame = 2 
Query:  245 CPILQTRNCCNSVILKEMSSVSEIKLKGFAEEKLENLLTMFSNDSYILMNMYLNDLENTKNDLNQLFSATYGYNYKVEKNFFFSWFDKLKMYMEGKKHNIGQLLDEFFLEMAGKIVKILIPPESSPEVTKCQIDRLIEA-KPYQEADNSLKKNIIRSYAPSRMFVNAIAVGRDGFRALMNKITPSSNCVAQFNTQFHCMLCNGL-TVKTCPVSCKSVMENCFGSFKLAELKKLDKIFTKYLSALFELANKLDNQLNFPAVNHKMNVQISTAIMNIQNIYPTIKEQIKAKC-------QNTGSKVRRKR 1141
            CP  Q   CC S + + +++ S  +L+    +    L  M +       + + + L +++  L   F   +G  Y      F   + +L++Y  G   ++ + L EF+  +  ++ K L P    P+     + +  EA +P+ EA   L+    R++  +R FV  + V  D  R +  ++     C        +C  C G+   + CP  C++V++ C     LA    LD  +   L ++  + +K        +V   ++  ++ AI  +Q+   T+  ++   C       Q  G + +R+R
Sbjct:   62 CP--QGYTCCTSEMEENLANRSHAELETALRDSSRVLQAMLATQLRSFDDHFQHLLNDSERTLQATFPGAFGELYTQNARAFRDLYSELRLYYRGANLHLEETLAEFWARLLERLFKQLHPQLLLPDDYLDCLGKQAEALRPFGEAPRELRLRATRAFVAARSFVQGLGVASDVVRKVA-QVPLGPECSRAVMKLVYCAHCLGVPGARPCPDYCRNVLKGC-----LANQADLDAEWRNLLDSMVLITDKFWGTSGVESVIGSVHTWLAEAINALQDNRDTLTAKVIQGCGNPKVNPQGPGPEEKRRR 361
[Close]
BLAST of Glypican-1 vs. Ensembl Human
Match: GPC1 (glypican 1 [Source:HGNC Symbol;Acc:HGNC:4449])

HSP 1 Score: 71.2478 bits (173), Expect = 1.339e-12
Identity = 58/256 (22.66%), Postives = 108/256 (42.19%), Query Frame = 2 
Query:  401 LNDLENTKNDLNQLFSATYGYNYKVEKNFFFSWFDKLKMYMEGKKHNIGQLLDEFFLEMAGKIVKILIPPESSPEVTKCQIDRLIEA-KPYQEADNSLKKNIIRSYAPSRMFVNAIAVGRDGFRALMNKITPSSNCVAQFNTQFHCMLCNGL-TVKTCPVSCKSVMENCFGSFKLAELKKLDKIFTKYLSALFELANKLDNQLNFPAVNHKMNVQISTAIMNIQNIYPTIKEQIKAKC-------QNTGSKVRRKR 1141
            LND E T   L   F   +G  Y      F   + +L++Y  G   ++ + L EF+  +  ++ K L P    P+     + +  EA +P+ EA   L+    R++  +R FV  + V  D  R +  ++     C        +C  C G+   + CP  C++V++ C     LA    LD  +   L ++  + +K        +V   ++  ++ AI  +Q+   T+  ++   C       Q  G + +R+R
Sbjct:   43 LNDSERT---LQATFPGAFGELYTQNARAFRDLYSELRLYYRGANLHLEETLAEFWARLLERLFKQLHPQLLLPDDYLDCLGKQAEALRPFGEAPRELRLRATRAFVAARSFVQGLGVASDVVRKVA-QVPLGPECSRAVMKLVYCAHCLGVPGARPCPDYCRNVLKGC-----LANQADLDAEWRNLLDSMVLITDKFWGTSGVESVIGSVHTWLAEAINALQDNRDTLTAKVIQGCGNPKVNPQGPGPEEKRRR 289
[Close]
BLAST of Glypican-1 vs. Ensembl Fly
Match: dlp (gene:FBgn0041604 transcript:FBtr0333032)

HSP 1 Score: 95.9005 bits (237), Expect = 1.032e-19
Identity = 62/281 (22.06%), Postives = 129/281 (45.91%), Query Frame = 2 
Query:  269 CCNSVILKEMSSVSEIKLKGFAEEKLENLLTMFSNDSYILMNMYLNDLENTKNDLNQLFSATYGYNYKVEKNFFFSWFDKLKMYMEGKKHNIGQLLDEFFLEMAGKIVKILIPPESSPE-VTKCQIDRLIEAKPYQEADNSLKKNIIRSYAPSRMFVNAIAVGRDGFRALMNKITPSSNCVAQFNTQFHCMLCNGLTVKTCPVSCKSVMENCFGSFKLAELKKLDKIFTKYLSALFELANKLDNQLNFPAVNHKMNVQISTAIMNIQNIYPTIKEQIKAKC 1108
            CC   +   M+  S  +L+G  ++++  +  +  + +    +++   L+ ++   N +F  TYG  Y+     F   F +L+ Y    + ++ +++D+FF  +  K+  +L    +  E   +C  + + E KP+ +  + L   I RS+  +R +  A+    +  + ++N +  +++C        HC  C G T K C   C +V++ C     L    + D  +  +  A+ ++A +L    N   V   +N++IS AIMN Q+    I  ++   C
Sbjct:  118 CCTYNMETRMAMQSRQQLEGHTKDQISRMSGILGSKATKFKDIFTALLKESRTQFNSMFIRTYGVIYERNSYVFSDLFKELETYFANGRVDLLEVMDKFFNTLYQKMFTVLNTQYTFDENYMRCVSEHMKELKPFGDVPDKLSVQIKRSFVATRTYGQALTTASEVAKKVLN-VRLNADCTGALTKMQHCGACKGYTEKPCTNYCVNVIKGC-----LHYQHEFDSEWENFAMAMDKVAERLLGSFNIVMVVEPLNIKISEAIMNFQDSGQDITNRVFQGC 392
[Close]
BLAST of Glypican-1 vs. Ensembl Fly
Match: dlp (gene:FBgn0041604 transcript:FBtr0075679)

HSP 1 Score: 95.9005 bits (237), Expect = 1.043e-19
Identity = 62/281 (22.06%), Postives = 129/281 (45.91%), Query Frame = 2 
Query:  269 CCNSVILKEMSSVSEIKLKGFAEEKLENLLTMFSNDSYILMNMYLNDLENTKNDLNQLFSATYGYNYKVEKNFFFSWFDKLKMYMEGKKHNIGQLLDEFFLEMAGKIVKILIPPESSPE-VTKCQIDRLIEAKPYQEADNSLKKNIIRSYAPSRMFVNAIAVGRDGFRALMNKITPSSNCVAQFNTQFHCMLCNGLTVKTCPVSCKSVMENCFGSFKLAELKKLDKIFTKYLSALFELANKLDNQLNFPAVNHKMNVQISTAIMNIQNIYPTIKEQIKAKC 1108
            CC   +   M+  S  +L+G  ++++  +  +  + +    +++   L+ ++   N +F  TYG  Y+     F   F +L+ Y    + ++ +++D+FF  +  K+  +L    +  E   +C  + + E KP+ +  + L   I RS+  +R +  A+    +  + ++N +  +++C        HC  C G T K C   C +V++ C     L    + D  +  +  A+ ++A +L    N   V   +N++IS AIMN Q+    I  ++   C
Sbjct:  118 CCTYNMETRMAMQSRQQLEGHTKDQISRMSGILGSKATKFKDIFTALLKESRTQFNSMFIRTYGVIYERNSYVFSDLFKELETYFANGRVDLLEVMDKFFNTLYQKMFTVLNTQYTFDENYMRCVSEHMKELKPFGDVPDKLSVQIKRSFVATRTYGQALTTASEVAKKVLN-VRLNADCTGALTKMQHCGACKGYTEKPCTNYCVNVIKGC-----LHYQHEFDSEWENFAMAMDKVAERLLGSFNIVMVVEPLNIKISEAIMNFQDSGQDITNRVFQGC 392
[Close]
BLAST of Glypican-1 vs. Ensembl Zebrafish
Match: gpc6b (glypican 6b [Source:ZFIN;Acc:ZDB-GENE-130515-2])

HSP 1 Score: 125.946 bits (315), Expect = 1.725e-29
Identity = 99/393 (25.19%), Postives = 173/393 (44.02%), Query Frame = 2 
Query:  269 CCNSVILKEMSSVSEIKLKGFAEEKLENLLTMFSNDSYILMNMYLNDLENTKNDLNQLFSATYGYNYKVEKNFFFSWFDKLKMYMEGKKHNIGQLLDEFFLEMAGKIVKILIPP-ESSPEVTKCQIDRLIEAKPYQEADNSLKKNIIRSYAPSRMFVNAIAVGRDGFRALMNKITPSSNCVAQFNTQFHCMLCNGL-TVKTCPVSCKSVMENCFGSFKLAELKKLDKIFTKYLSALFELANKLDNQLNFPAVNHKMNVQISTAIMNIQNIYPTIKEQIKAKCQN--TGSKVRRKRQVAKEFVAWQTKLGDESPFWKKKLNDNLKSGVSKKTPVGSQNTKLNDFLSPMSRRIKTKYKALEGYFLRGVHDFCTLN--SQSNESSSTQCWNGTLPG 1429
            CCN+ + +  S  S    +   ++  E L   F +      + +L  LE+ +  LN++F  TYG  Y      F S F +L+ +  G   N+ ++L +F+  +  ++ ++L    + + E  +C      + +P+ +    LK  + R++  +R FV  +AVGRD     + +++ SS+CV+ F    +C  C GL T+K C   C +VM+ C     LA    L+  ++K++ AL  L  +L+   N  +V   ++V+IS AIMN+Q     +  Q+   C         R  R V   F       G   P+              ++ P  +    L+  +S M    K K K  + +++     FC     S   ++   QCWNG   G
Sbjct:   57 CCNTQMEESFSHRSSHDFQKLMDDASEELRDTFMSGHKRFDDFFLELLESAERSLNEMFVRTYGKPYLQNAEVFQSLFSELRRFYTGGNVNLEEMLKDFWTRLLERMFQLLNSQFQITDEYLECIGKYTEQLRPFGDVPKKLKSQVTRAFIAARTFVQGLAVGRD-VANRVAQVSMSSSCVSGFTKMLYCSYCQGLFTLKPCRNYCLNVMKGC-----LANQADLNNEWSKFIDALLLLTERLEGPFNIESVMEPIDVKISEAIMNMQENSMQLSYQVFQGCGQPEPAGMTRSARSVHDSFS------GRFKPY--------------EELPTVASGAPLHRLVSEM----KEKLKHFQSFWVSLPLVFCKDEQISADGQTEDQQCWNGHHSG 419
[Close]
BLAST of Glypican-1 vs. Ensembl Zebrafish
Match: gpc6a (glypican 6a [Source:ZFIN;Acc:ZDB-GENE-071004-15])

HSP 1 Score: 112.849 bits (281), Expect = 3.308e-25
Identity = 75/305 (24.59%), Postives = 143/305 (46.89%), Query Frame = 2 
Query:  257 QTRNCCNSVILKEMSSVSEIKLKGFAEEKLENLLTMFSNDSYILMNMYLNDLENTKNDLNQLFSATYGYNYKVEKNFFFSWFDKLKMYMEGKKHNIGQLLDEFFLEMAGKIVKILIPPES-SPEVTKCQIDRLIEAKPYQEADNSLKKNIIRSYAPSRMFVNAIAVGRDGFRALMNKITPSSNCVAQFNTQFHCMLCNGLT-VKTCPVSCKSVMENCFGSFKLAELKKLDKIFTKYLSALFELANKLDNQLNFPAVNHKMNVQISTAIMNIQNIYPTIKEQIKAKCQN--TGSKVRRKRQVAKEF 1159
            Q   CC S I  ++   S++  +   ++   N+ T F++        +L  L+N++  LN +F  TYG  Y      F   F +LK Y  G   N+ ++L++F+  +  ++ ++L    + S +  +C      + KP+ +    LK  + +++  +R FV  + VGR+     + K+  S  C       ++C  C G++ +K C   C++VM  C     LA    LD  +  ++ A+  +A++L+   N  AV   ++V+IS AIM +Q+    +  ++   C +    S  R  R ++  F
Sbjct:   61 QGYTCCTSDIEDQLGQQSKLDFERLVDDSSRNIRTTFTSRHKKFDEFFLELLDNSEKSLNDMFVRTYGKLYTHNSEMFEDLFSELKRYYTGGNVNLEEVLNDFWSRLLERMFQLLNSQFTFSDDYLECISKYTDQLKPFGDVPRKLKAQVTKAFIAARSFVQGLMVGRE-VANRVAKVNISPGCSKALTKMWYCPYCGGMSGLKPCANYCQNVMRGC-----LANQADLDPEWNLFIDAMLLVADRLEGPFNIEAVMEPIDVKISEAIMTMQDNSMQVSSKVFQGCGHPKAASVGRSARGISDVF 359
[Close]
BLAST of Glypican-1 vs. Ensembl Zebrafish
Match: gpc4 (glypican 4 [Source:ZFIN;Acc:ZDB-GENE-011119-1])

HSP 1 Score: 110.538 bits (275), Expect = 1.764e-24
Identity = 87/332 (26.20%), Postives = 153/332 (46.08%), Query Frame = 2 
Query:  179 YSLKYPYLNLLENYKLQNTAFN-CPILQTRNCCNSVILKEMSSVSEIKLKGFAEEKLENLLTMFSNDSYILMNMYLNDLENTKNDLNQLFSATYGYNYKVEKNFFFSWFDKLKMYME--GKKHNIGQLLDEFFLEMAGKIVKIL-IPPESSPEVTKCQIDRLIEAKPYQEADNSLKKNIIRSYAPSRMFVNAIAVGRDGFRALMNKITPSSNCVAQFNTQFHCMLCNG-LTVKTCPVSCKSVMENCFGSFKLAELKKLDKIFTKYLSALFELANKLDNQLNFPAVNHKMNVQISTAIMNIQNIYPTIKEQIKAKC-QNTGSKVRRKRQVAKE 1156
            YS K   +N + N  +Q      CP  Q  +CC   + +++S +S + LK    +   NL + F+         +   L+N +  LN +F  TYG  Y   K  F  +F  L+ Y      + N+  +L EF+ E+  ++ +++ +  E S    +C      + KP+ +    L+  + RS+   R F   + +  D  R + + ++ S +CV       +C  C+G + +K C   C +VM  C     LA    LD  +  +L ++  LA +L+   NF +V   ++V+IS AIMN+Q     + +++   C Q   S   R R+ AK+
Sbjct:   35 YSSKGFNVNDVPNKGVQGAHLKVCP--QGFSCCTLEMEEKLSQLSHVDLKVPVHQLSSNLQSTFTQRHRHFDQFFRELLDNAEKSLNHMFVRTYGLMYVKNKELFEGFFSDLRRYYSHGSSEVNLDDMLAEFWSELLERMFRLVNVQYEFSDSYMECVSRHTDQLKPFGDVPRKLRLQLTRSFIAVRAFTRGLTLMPDVVRKV-STVSASPSCVRASMKMLYCPYCSGQVALKPCKNYCLNVMRGC-----LANQADLDTEWNNFLDSMLGLAERLEGPFNFESVVDPIDVKISDAIMNMQENSMQVSQKVFQGCGQPKLSMGFRSRRSAKD 358
[Close]
BLAST of Glypican-1 vs. Ensembl Zebrafish
Match: gpc1a (glypican 1a [Source:NCBI gene;Acc:553367])

HSP 1 Score: 96.6709 bits (239), Expect = 4.858e-20
Identity = 66/298 (22.15%), Postives = 133/298 (44.63%), Query Frame = 2 
Query:  245 CPILQTRNCCNSVILKEMSSVSEIKLKGFAEEKLENLLTMFSNDSYILMNMYLNDLENTKNDLNQLFSATYGYNYKVEKNFFFSWFDKLKMYMEGKKHNIGQLLDEFFLEMAGKIVKILIPPESS---PEVTKCQIDRLIEAKPYQEADNSLKKNIIRSYAPSRMFVNAIAVGRDGFRALMNKITPSSNCVAQFNTQFHCMLCNGL-TVKTCPVSCKSVMENCFGSFKLAELKKLDKIFTKYLSALFELANKLDNQLNFPAVNHKMNVQISTAIMNIQNIYPTIKEQIKAKCQNTGSK 1126
            CP  Q   CC S + + +S++S  + +G   E   ++  + +         +L  L  ++  L + F A  G  Y++    F   + +L  Y  G   N+ + LDEF++++  +++K   P  +S    +   C   +    +P+ +A   LK  ++R++  +R FV  +    +  R + +++  S  C        +C  C GL +VK C   CK+VM+ C     LA    LD  +   +  + ++A+    + +   V + + V+IS A++ +Q        ++   C + G +
Sbjct:   68 CP--QGYTCCTSAMEETLSNLSRREFEGLVREAGRSIQALLNAQYRTFDTYFLELLNGSERWLEEAFVAALGELYRLNAGVFRDLYAELHRYYSGASLNLEEALDEFWMKLLERLLKASDPETASLLSDDFLDCASKQTETLRPFGDAPRELKAKLVRAFIAARAFVQGLNAAGEIVRKV-SQVPLSPECNRAIMKLVYCPHCRGLGSVKPCINYCKNVMKGC-----LANQADLDTEWQSLIETMLQVASSFGAEPSMDTVIYSIPVRISEAVLAMQENMEIYTSKVFKACGDRGEE 357
[Close]
BLAST of Glypican-1 vs. Ensembl Zebrafish
Match: gpc1a (glypican 1a [Source:NCBI gene;Acc:553367])

HSP 1 Score: 95.9005 bits (237), Expect = 6.568e-20
Identity = 66/298 (22.15%), Postives = 133/298 (44.63%), Query Frame = 2 
Query:  245 CPILQTRNCCNSVILKEMSSVSEIKLKGFAEEKLENLLTMFSNDSYILMNMYLNDLENTKNDLNQLFSATYGYNYKVEKNFFFSWFDKLKMYMEGKKHNIGQLLDEFFLEMAGKIVKILIPPESS---PEVTKCQIDRLIEAKPYQEADNSLKKNIIRSYAPSRMFVNAIAVGRDGFRALMNKITPSSNCVAQFNTQFHCMLCNGL-TVKTCPVSCKSVMENCFGSFKLAELKKLDKIFTKYLSALFELANKLDNQLNFPAVNHKMNVQISTAIMNIQNIYPTIKEQIKAKCQNTGSK 1126
            CP  Q   CC S + + +S++S  + +G   E   ++  + +         +L  L  ++  L + F A  G  Y++    F   + +L  Y  G   N+ + LDEF++++  +++K   P  +S    +   C   +    +P+ +A   LK  ++R++  +R FV  +    +  R + +++  S  C        +C  C GL +VK C   CK+VM+ C     LA    LD  +   +  + ++A+    + +   V + + V+IS A++ +Q        ++   C + G +
Sbjct:   59 CP--QGYTCCTSAMEETLSNLSRREFEGLVREAGRSIQALLNAQYRTFDTYFLELLNGSERWLEEAFVAALGELYRLNAGVFRDLYAELHRYYSGASLNLEEALDEFWMKLLERLLKASDPETASLLSDDFLDCASKQTETLRPFGDAPRELKAKLVRAFIAARAFVQGLNAAGEIVRKV-SQVPLSPECNRAIMKLVYCPHCRGLGSVKPCINYCKNVMKGC-----LANQADLDTEWQSLIETMLQVASSFGAEPSMDTVIYSIPVRISEAVLAMQENMEIYTSKVFKACGDRGEE 348
[Close]
BLAST of Glypican-1 vs. Ensembl Xenopus
Match: GPC4 (glypican 4 [Source:NCBI gene;Acc:100126682])

HSP 1 Score: 120.939 bits (302), Expect = 9.370e-28
Identity = 95/395 (24.05%), Postives = 176/395 (44.56%), Query Frame = 2 
Query:  257 QTRNCCNSVILKEMSSVSEIKLKGFAEEKLENLLTMFSNDSYILMNMYLNDLENTKNDLNQLFSATYGYNYKVEKNFFFSWFDKLKMYMEGKKHNIGQLLDEFFLEMAGKIVKILIPP-ESSPEVTKCQIDRLIEAKPYQEADNSLKKNIIRSYAPSRMFVNAIAVGRDGFRALMNKIT---PSSNCVAQFNTQFHCMLCNGL-TVKTCPVSCKSVMENCFGSFKLAELKKLDKIFTKYLSALFELANKLDNQLNFPAVNHKMNVQISTAIMNIQNIYPTIKEQIKAKCQNTG--SKVRRKRQVAKEFVAWQTKLGDESPFWKKKLNDNLKSGVSKKTPVGSQNTKLNDFLSPMSRRIKTKYKALEGYFLRGVHDFCTLNSQSNESSSTQCWNGT 1420
            Q   CC+  + ++ S  S+   K    E   N+  +F++        +   L+N +N LN +F  TYG  Y      F  +F +LK Y  G   N+ ++L++F+  +  ++ +++ P  + + E  +C      + KP+ +    LK  + R++  +R F   ++V RD    ++NK++   P+  CV       +C  C+GL TVK C   C +VM  C     LA    LD  +  ++ A+  +A +L+   N   V   ++V+IS AIMN+Q     + +++   C      S+ R+ R V+                     N   +S   ++ P  +  T L+  ++ +  ++KT  K     F   +      N+ ++ +S   CWNG+
Sbjct:   62 QRHTCCSLAMEEKYSQQSKHDFKVAVIEPCNNMQHIFASRFNKFDEFFKELLQNAENSLNDMFVRTYGRLYMQNSELFKDFFVELKKYYVGGNVNLEEMLNDFWARLLERMFRLVNPQYQFTDEYLECVSKYTDQLKPFGDVPRKLKLQVTRAFVAARTFAQGLSVARD----VINKVSSVNPTPQCVKAMLKMTYCPYCSGLVTVKPCNNYCLNVMRGC-----LANPGDLDTEWNNFIDAMLLVAERLEGPFNIETVMDPIDVKISDAIMNMQENSMQVSQKVFQGCGQPKPLSQGRQARSVSDS-----------------NFNSRFRSYGPEERPTTAAGTSLDRLVADVKEKLKTAKK-----FWSSLPGSICKNNWTSGASEDDCWNGS 425
[Close]
BLAST of Glypican-1 vs. Ensembl Xenopus
Match: GPC6 (glypican 6 [Source:NCBI gene;Acc:100491173])

HSP 1 Score: 107.457 bits (267), Expect = 1.970e-23
Identity = 72/276 (26.09%), Postives = 132/276 (47.83%), Query Frame = 2 
Query:  245 CPILQTRNCCNSVILKEMSSVSEIKLKGFAEEKLENLLTMFSNDSYILMNMYLNDLENTKNDLNQLFSATYGYNYKVEKNFFFSWFDKLKMYMEGKKHNIGQLLDEFFLEMAGKIVKILIPP-ESSPEVTKCQIDRLIEAKPYQEADNSLKKNIIRSYAPSRMFVNAIAVGRDGFRALMNKITPSSNCVAQFNTQFHCMLCNGL-TVKTCPVSCKSVMENCFGSFKLAELKKLDKIFTKYLSALFELANKLDNQLNFPAVNHKMNVQISTAIMNIQ 1066
            CP  Q   CC S +  ++S  S+++ +   EE    +   F +        +   L+N +  LN +F  TYG  Y      F   F +LK Y  G   N+ ++L++F+  +  ++ +++ P    S +  +C      + KP+ +    LK  + R+   +R FV  + VGR+     ++KI+P+  C+       +C  C GL +V+ C   C +VM+ C     LA    LD  +  ++ A+  + ++L+   N  +V   ++V+IS AI+N+Q
Sbjct:   59 CP--QEYTCCTSEMEDKLSQQSKLEFESLVEETSHFVRATFVSWHRKFDEFFRELLKNAEKSLNDMFVNTYGMLYMQNTEVFQDLFTELKRYYTGGNVNLEEILNDFWARLLERMFQLINPQYHFSEDYLECVSKYTDQLKPFGDIPRKLKVQVTRALIAARTFVQGLTVGRE-VANRVSKISPNPGCIRALMKMLYCPYCRGLPSVRPCSNYCLNVMKGC-----LANQADLDIEWNLFIDAMLLVVDRLEGPFNIESVMGPIDVKISEAIVNMQ 326
[Close]
BLAST of Glypican-1 vs. Ensembl Xenopus
Match: atf2 (activating transcription factor 2 [Source:Xenbase;Acc:XB-GENE-961088])

HSP 1 Score: 86.6557 bits (213), Expect = 6.638e-17
Identity = 88/406 (21.67%), Postives = 159/406 (39.16%), Query Frame = 2 
Query:  245 CPILQTRNCCNSVILKEMSSVSEIKLKGFAEEK---LENLLTMFSNDSYILMNMYLNDLENTKND-LNQLFSATYGYNYKVEKNFFFSWFDKLKMYMEGKKHNIGQLLDEFFLEMAGKIVKILIPPES-SPEVTKCQIDRLIEAKPYQEADNSLKKNIIRSYAPSRMFVNAIAVGRDGFRALMNKITPSSNCVAQFNTQFHCMLCNGLT-VKTCPVSCKSVMENCFGSFKLAELKKLDKIFTKYLSALFELANKLDNQLNFPAVNHKMNVQISTAIMNIQNIYPTIKEQIKAKC-----QNTGSKVRRKRQVAKEFVAWQTKLGDESPFWKKKLNDNLKSGVSKKTPVGSQNTKLNDFLSPMSRRIKTKYKALEGYFLRGVHDFCTLNSQSNESSSTQCWNGTLPG 1429
            CP  Q   CC S + +  +++S ++ +    E    ++ LLT    +     + Y  DL NT    L + F + YG  Y      F   + +L+ Y  G   N+ + L EF+  +  ++ K      S S E   C + +  + KP+ +    +K    R++  +R FV  +    D  R   N++  S+ C        +C  C G + +K C   C +VM  C     LA    LD  +   + +L  +A+K +   N   +   ++ +IS AI ++Q     +  ++   C      N GSK   +R+  K                         +    K+ V + +  ++D        +K     ++ Y++     FCT    +   +  +CWNG   G
Sbjct:   66 CP--QGYTCCTSEMEENFANISRVEFEAKLRESSASIQRLLTTQHRN----FDSYFQDLLNTSERVLQERFPSQYGDLYSQNSKIFRDLYSELRQYYRGSGINLEEALIEFWSRLLERVFKAQHTQYSFSEEYMDCLVKQYEQLKPFGDTPREVKLKAARAFIAARSFVQGLNAAADVVRK-ANQVPMSTECARAVMKLVYCPHCRGHSSIKLCSNYCWNVMRGC-----LANQADLDSEWRNLIESLLLVADKFNGASNVENIVGAIHTKISEAITHMQENKELLTNKVFKICGTPKKTNKGSKSEERRRKGK-------------------------ATQEDKSAVATMDNLISD--------VKGILSDIQDYWVSLPSLFCTEKVTAGPGNEDKCWNGITKG 426
[Close]
BLAST of Glypican-1 vs. Ensembl Xenopus
Match: atf2 (activating transcription factor 2 [Source:Xenbase;Acc:XB-GENE-961088])

HSP 1 Score: 86.2705 bits (212), Expect = 7.892e-17
Identity = 88/406 (21.67%), Postives = 159/406 (39.16%), Query Frame = 2 
Query:  245 CPILQTRNCCNSVILKEMSSVSEIKLKGFAEEK---LENLLTMFSNDSYILMNMYLNDLENTKND-LNQLFSATYGYNYKVEKNFFFSWFDKLKMYMEGKKHNIGQLLDEFFLEMAGKIVKILIPPES-SPEVTKCQIDRLIEAKPYQEADNSLKKNIIRSYAPSRMFVNAIAVGRDGFRALMNKITPSSNCVAQFNTQFHCMLCNGLT-VKTCPVSCKSVMENCFGSFKLAELKKLDKIFTKYLSALFELANKLDNQLNFPAVNHKMNVQISTAIMNIQNIYPTIKEQIKAKC-----QNTGSKVRRKRQVAKEFVAWQTKLGDESPFWKKKLNDNLKSGVSKKTPVGSQNTKLNDFLSPMSRRIKTKYKALEGYFLRGVHDFCTLNSQSNESSSTQCWNGTLPG 1429
            CP  Q   CC S + +  +++S ++ +    E    ++ LLT    +     + Y  DL NT    L + F + YG  Y      F   + +L+ Y  G   N+ + L EF+  +  ++ K      S S E   C + +  + KP+ +    +K    R++  +R FV  +    D  R   N++  S+ C        +C  C G + +K C   C +VM  C     LA    LD  +   + +L  +A+K +   N   +   ++ +IS AI ++Q     +  ++   C      N GSK   +R+  K                         +    K+ V + +  ++D        +K     ++ Y++     FCT    +   +  +CWNG   G
Sbjct:   42 CP--QGYTCCTSEMEENFANISRVEFEAKLRESSASIQRLLTTQHRN----FDSYFQDLLNTSERVLQERFPSQYGDLYSQNSKIFRDLYSELRQYYRGSGINLEEALIEFWSRLLERVFKAQHTQYSFSEEYMDCLVKQYEQLKPFGDTPREVKLKAARAFIAARSFVQGLNAAADVVRK-ANQVPMSTECARAVMKLVYCPHCRGHSSIKLCSNYCWNVMRGC-----LANQADLDSEWRNLIESLLLVADKFNGASNVENIVGAIHTKISEAITHMQENKELLTNKVFKICGTPKKTNKGSKSEERRRKGK-------------------------ATQEDKSAVATMDNLISD--------VKGILSDIQDYWVSLPSLFCTEKVTAGPGNEDKCWNGITKG 402
[Close]
BLAST of Glypican-1 vs. Ensembl Xenopus
Match: atf2 (activating transcription factor 2 [Source:Xenbase;Acc:XB-GENE-961088])

HSP 1 Score: 86.6557 bits (213), Expect = 1.054e-16
Identity = 88/406 (21.67%), Postives = 159/406 (39.16%), Query Frame = 2 
Query:  245 CPILQTRNCCNSVILKEMSSVSEIKLKGFAEEK---LENLLTMFSNDSYILMNMYLNDLENTKND-LNQLFSATYGYNYKVEKNFFFSWFDKLKMYMEGKKHNIGQLLDEFFLEMAGKIVKILIPPES-SPEVTKCQIDRLIEAKPYQEADNSLKKNIIRSYAPSRMFVNAIAVGRDGFRALMNKITPSSNCVAQFNTQFHCMLCNGLT-VKTCPVSCKSVMENCFGSFKLAELKKLDKIFTKYLSALFELANKLDNQLNFPAVNHKMNVQISTAIMNIQNIYPTIKEQIKAKC-----QNTGSKVRRKRQVAKEFVAWQTKLGDESPFWKKKLNDNLKSGVSKKTPVGSQNTKLNDFLSPMSRRIKTKYKALEGYFLRGVHDFCTLNSQSNESSSTQCWNGTLPG 1429
            CP  Q   CC S + +  +++S ++ +    E    ++ LLT    +     + Y  DL NT    L + F + YG  Y      F   + +L+ Y  G   N+ + L EF+  +  ++ K      S S E   C + +  + KP+ +    +K    R++  +R FV  +    D  R   N++  S+ C        +C  C G + +K C   C +VM  C     LA    LD  +   + +L  +A+K +   N   +   ++ +IS AI ++Q     +  ++   C      N GSK   +R+  K                         +    K+ V + +  ++D        +K     ++ Y++     FCT    +   +  +CWNG   G
Sbjct:   73 CP--QGYTCCTSEMEENFANISRVEFEAKLRESSASIQRLLTTQHRN----FDSYFQDLLNTSERVLQERFPSQYGDLYSQNSKIFRDLYSELRQYYRGSGINLEEALIEFWSRLLERVFKAQHTQYSFSEEYMDCLVKQYEQLKPFGDTPREVKLKAARAFIAARSFVQGLNAAADVVRK-ANQVPMSTECARAVMKLVYCPHCRGHSSIKLCSNYCWNVMRGC-----LANQADLDSEWRNLIESLLLVADKFNGASNVENIVGAIHTKISEAITHMQENKELLTNKVFKICGTPKKTNKGSKSEERRRKGK-------------------------ATQEDKSAVATMDNLISD--------VKGILSDIQDYWVSLPSLFCTEKVTAGPGNEDKCWNGITKG 433
[Close]
BLAST of Glypican-1 vs. Ensembl Mouse
Match: Gpc6 (glypican 6 [Source:MGI Symbol;Acc:MGI:1346322])

HSP 1 Score: 121.324 bits (303), Expect = 5.669e-28
Identity = 93/395 (23.54%), Postives = 168/395 (42.53%), Query Frame = 2 
Query:  245 CPILQTRNCCNSVILKEMSSVSEIKLKGFAEEKLENLLTMFSNDSYILMNMYLNDLENTKNDLNQLFSATYGYNYKVEKNFFFSWFDKLKMYMEGKKHNIGQLLDEFFLEMAGKIVKILIPP-ESSPEVTKCQIDRLIEAKPYQEADNSLKKNIIRSYAPSRMFVNAIAVGRDGFRALMNKITPSSNCVAQFNTQFHCMLCNGL-TVKTCPVSCKSVMENCFGSFKLAELKKLDKIFTKYLSALFELANKLDNQLNFPAVNHKMNVQISTAIMNIQNIYPTIKEQIKAKCQN--TGSKVRRKRQVAKEFVAWQTKLGDESPFWKKKLNDNLKSGVSKKTPVGSQNTKLNDFLSPMSRRIKTKYKALEGYFLRGVHDFCTLNSQSNESSSTQCWNG 1417
            CP  Q   CC + +  ++S  S+++ +   EE    + T F +        +   LEN +  LN +F  TYG  Y      F   F +LK Y  G   N+ ++L++F+  +  ++ +++ P    S +  +C      + KP+ +    LK  + R++  +R FV  + VGR+     ++K++P+  C+       +C  C GL TV+ C   C +VM+ C     LA    LD  +  ++ A+  +A +L+   N  +V   ++V+IS AIMN+Q     +  ++   C        +R  R   + F                  N   +    ++ P  +  T L+  ++ +  ++K   K           D       SNE    +CWNG
Sbjct:   60 CP--QEYTCCTTEMEDKLSQQSKLEFENLVEETSHFVRTTFVSRHKKFDEFFRELLENAEKSLNDMFVRTYGMLYMQNSEVFQDLFTELKRYYTGGNVNLEEMLNDFWARLLERMFQLINPQYHFSEDYLECVSKYTDQLKPFGDVPRKLKIQVTRAFIAARTFVQGLTVGRE-VANRVSKVSPTPGCIRALMKMLYCPYCRGLPTVRPCNNYCLNVMKGC-----LANQADLDTEWNLFIDAMLLVAERLEGPFNIESVMDPIDVKISEAIMNMQENSMQVSAKVFQGCGQPKPAPALRSARSAPENF------------------NTRFRPYNPEERPTTAAGTSLDRLVTDIKEKLKLSKKVWSALPYTICKDERVTAGTSNEE---ECWNG 425
[Close]
BLAST of Glypican-1 vs. Ensembl Mouse
Match: Gpc6 (glypican 6 [Source:MGI Symbol;Acc:MGI:1346322])

HSP 1 Score: 121.324 bits (303), Expect = 5.669e-28
Identity = 93/395 (23.54%), Postives = 168/395 (42.53%), Query Frame = 2 
Query:  245 CPILQTRNCCNSVILKEMSSVSEIKLKGFAEEKLENLLTMFSNDSYILMNMYLNDLENTKNDLNQLFSATYGYNYKVEKNFFFSWFDKLKMYMEGKKHNIGQLLDEFFLEMAGKIVKILIPP-ESSPEVTKCQIDRLIEAKPYQEADNSLKKNIIRSYAPSRMFVNAIAVGRDGFRALMNKITPSSNCVAQFNTQFHCMLCNGL-TVKTCPVSCKSVMENCFGSFKLAELKKLDKIFTKYLSALFELANKLDNQLNFPAVNHKMNVQISTAIMNIQNIYPTIKEQIKAKCQN--TGSKVRRKRQVAKEFVAWQTKLGDESPFWKKKLNDNLKSGVSKKTPVGSQNTKLNDFLSPMSRRIKTKYKALEGYFLRGVHDFCTLNSQSNESSSTQCWNG 1417
            CP  Q   CC + +  ++S  S+++ +   EE    + T F +        +   LEN +  LN +F  TYG  Y      F   F +LK Y  G   N+ ++L++F+  +  ++ +++ P    S +  +C      + KP+ +    LK  + R++  +R FV  + VGR+     ++K++P+  C+       +C  C GL TV+ C   C +VM+ C     LA    LD  +  ++ A+  +A +L+   N  +V   ++V+IS AIMN+Q     +  ++   C        +R  R   + F                  N   +    ++ P  +  T L+  ++ +  ++K   K           D       SNE    +CWNG
Sbjct:   60 CP--QEYTCCTTEMEDKLSQQSKLEFENLVEETSHFVRTTFVSRHKKFDEFFRELLENAEKSLNDMFVRTYGMLYMQNSEVFQDLFTELKRYYTGGNVNLEEMLNDFWARLLERMFQLINPQYHFSEDYLECVSKYTDQLKPFGDVPRKLKIQVTRAFIAARTFVQGLTVGRE-VANRVSKVSPTPGCIRALMKMLYCPYCRGLPTVRPCNNYCLNVMKGC-----LANQADLDTEWNLFIDAMLLVAERLEGPFNIESVMDPIDVKISEAIMNMQENSMQVSAKVFQGCGQPKPAPALRSARSAPENF------------------NTRFRPYNPEERPTTAAGTSLDRLVTDIKEKLKLSKKVWSALPYTICKDERVTAGTSNEE---ECWNG 425
[Close]
BLAST of Glypican-1 vs. Ensembl Mouse
Match: Gpc6 (glypican 6 [Source:MGI Symbol;Acc:MGI:1346322])

HSP 1 Score: 117.857 bits (294), Expect = 8.105e-27
Identity = 75/276 (27.17%), Postives = 134/276 (48.55%), Query Frame = 2 
Query:  245 CPILQTRNCCNSVILKEMSSVSEIKLKGFAEEKLENLLTMFSNDSYILMNMYLNDLENTKNDLNQLFSATYGYNYKVEKNFFFSWFDKLKMYMEGKKHNIGQLLDEFFLEMAGKIVKILIPP-ESSPEVTKCQIDRLIEAKPYQEADNSLKKNIIRSYAPSRMFVNAIAVGRDGFRALMNKITPSSNCVAQFNTQFHCMLCNGL-TVKTCPVSCKSVMENCFGSFKLAELKKLDKIFTKYLSALFELANKLDNQLNFPAVNHKMNVQISTAIMNIQ 1066
            CP  Q   CC + +  ++S  S+++ +   EE    + T F +        +   LEN +  LN +F  TYG  Y      F   F +LK Y  G   N+ ++L++F+  +  ++ +++ P    S +  +C      + KP+ +    LK  + R++  +R FV  + VGR+     ++K++P+  C+       +C  C GL TV+ C   C +VM+ C     LA    LD  +  ++ A+  +A +L+   N  +V   ++V+IS AIMN+Q
Sbjct:   60 CP--QEYTCCTTEMEDKLSQQSKLEFENLVEETSHFVRTTFVSRHKKFDEFFRELLENAEKSLNDMFVRTYGMLYMQNSEVFQDLFTELKRYYTGGNVNLEEMLNDFWARLLERMFQLINPQYHFSEDYLECVSKYTDQLKPFGDVPRKLKIQVTRAFIAARTFVQGLTVGRE-VANRVSKVSPTPGCIRALMKMLYCPYCRGLPTVRPCNNYCLNVMKGC-----LANQADLDTEWNLFIDAMLLVAERLEGPFNIESVMDPIDVKISEAIMNMQ 327
[Close]
BLAST of Glypican-1 vs. Ensembl Mouse
Match: Gpc4 (glypican 4 [Source:MGI Symbol;Acc:MGI:104902])

HSP 1 Score: 108.227 bits (269), Expect = 8.773e-24
Identity = 73/290 (25.17%), Postives = 136/290 (46.90%), Query Frame = 2 
Query:  245 CPILQTRNCCNSVILKEMSSVSEIKLKGFAEEKLENLLTMFSNDSYILMNMYLNDLENTKNDLNQLFSATYGYNYKVEKNFFFSWFDKLKMYMEGKKHNIGQLLDEFFLEMAGKIVKILIPP-ESSPEVTKCQIDRLIEAKPYQEADNSLKKNIIRSYAPSRMFVNAIAVGRDGFRALMNKITPSSNCVAQFNTQFHCMLCNGL-TVKTCPVSCKSVMENCFGSFKLAELKKLDKIFTKYLSALFELANKLDNQLNFPAVNHKMNVQISTAIMNIQNIYPTIKEQIKAKC 1108
            CP  Q   CC+  + ++ S  S+   K    E+  +L  +F++        +   LEN +  LN +F  TYG+ Y      F   F +LK Y      N+ ++L++F+  +  ++ +++      + E  +C      + KP+ +    LK  + R++  +R F   +AV RD   + ++ + P++ C        +C  C GL TVK C   C ++M  C     LA    LD  +  ++ A+  +A +L+   N  +V   ++V+IS AIMN+Q+    + +++   C
Sbjct:   60 CP--QDYTCCSQEMEEKYSLQSKDDFKTVVSEQCNHLQAIFASRYKKFDEFFKELLENAEKSLNDMFVKTYGHLYMQNSELFKDLFVELKRYYVAGNVNLEEMLNDFWARLLERMFRLVNSQYHFTDEYLECVSKYTEQLKPFGDVPRKLKLQVTRAFVAARTFAQGLAVARD-VVSKVSVVNPTAQCTHALLKMIYCSHCRGLVTVKPCYNYCSNIMRGC-----LANQGDLDFEWNNFIDAMLMVAERLEGPFNIESVMDPIDVKISDAIMNMQDNSVQVSQKVFQGC 341
[Close]
BLAST of Glypican-1 vs. Ensembl Mouse
Match: Gpc1 (glypican 1 [Source:MGI Symbol;Acc:MGI:1194891])

HSP 1 Score: 83.1889 bits (204), Expect = 8.297e-16
Identity = 63/309 (20.39%), Postives = 130/309 (42.07%), Query Frame = 2 
Query:  245 CPILQTRNCCNSVILKEMSSVSEIKLKGFAEEKLENLLTMFSNDSYILMNMYLNDLENTKNDLNQLFSATYGYNYKVEKNFFFSWFDKLKMYMEGKKHNIGQLLDEFFLEMAGKIVKILIPPESSPEVTKCQIDRLIEAKPYQEADNSLKKNIIRSYAPSRMFVNAIAVGRDGFRALMNKITPSSNCVAQFNTQFHCMLCNGL-TVKTCPVSCKSVMENCFGSFKLAELKKLDKIFTKYLSALFELANKLDNQLNFPAVNHKMNVQISTAIMNIQNIYPTIKEQIKAKCQN-----TGSKVRRKRQVAK 1153
            CP  Q   CC S + + +++ S ++L+    +    L    +   + + + +   L +++  L + F   +G  Y      F   + +L++Y  G   ++ + L EF+  +  ++ K L P     +   C   +    +P+ +A   L+    R++  +R FV  + V  D  R +  ++  +  C        +C  C G+   + CP  C++V++ C     LA    LD  +   L ++  + +K        +V   ++V ++ AI  +Q+   T+  ++   C N      GS    KR+  K
Sbjct:   62 CP--QGYTCCTSEMEENLANHSRMELESALHDSSRALQATLATQLHGIDDHFQRLLNDSERTLQEAFPGAFGDLYTQNTRAFRDLYAELRLYYRGANLHLEETLAEFWARLLERLFKQLHPQLLPDDYLDCLGKQAEALRPFGDAPRELRLRATRAFVAARSFVQGLGVASDVVRKVA-QVPLAPECSRAIMKLVYCAHCRGVPGARPCPDYCRNVLKGC-----LANQADLDAEWRNLLDSMVLITDKFWGPSGAESVIGGVHVWLAEAINALQDNKDTLTAKVIQACGNPKVNPHGSGPEEKRRRGK 362
[Close]
BLAST of Glypican-1 vs. UniProt/SwissProt
Match: sp|Q9Y625|GPC6_HUMAN (Glypican-6 OS=Homo sapiens OX=9606 GN=GPC6 PE=1 SV=1)

HSP 1 Score: 121.709 bits (304), Expect = 2.870e-27
Identity = 93/395 (23.54%), Postives = 168/395 (42.53%), Query Frame = 2 
Query:  245 CPILQTRNCCNSVILKEMSSVSEIKLKGFAEEKLENLLTMFSNDSYILMNMYLNDLENTKNDLNQLFSATYGYNYKVEKNFFFSWFDKLKMYMEGKKHNIGQLLDEFFLEMAGKIVKILIPP-ESSPEVTKCQIDRLIEAKPYQEADNSLKKNIIRSYAPSRMFVNAIAVGRDGFRALMNKITPSSNCVAQFNTQFHCMLCNGL-TVKTCPVSCKSVMENCFGSFKLAELKKLDKIFTKYLSALFELANKLDNQLNFPAVNHKMNVQISTAIMNIQNIYPTIKEQIKAKCQN--TGSKVRRKRQVAKEFVAWQTKLGDESPFWKKKLNDNLKSGVSKKTPVGSQNTKLNDFLSPMSRRIKTKYKALEGYFLRGVHDFCTLNSQSNESSSTQCWNG 1417
            CP  Q   CC + +  ++S  S+++ +   EE    + T F +        +   LEN +  LN +F  TYG  Y      F   F +LK Y  G   N+ ++L++F+  +  ++ +++ P    S +  +C      + KP+ +    LK  + R++  +R FV  + VGR+     ++K++P+  C+       +C  C GL TV+ C   C +VM+ C     LA    LD  +  ++ A+  +A +L+   N  +V   ++V+IS AIMN+Q     +  ++   C        +R  R   + F                  N   +    ++ P  +  T L+  ++ +  ++K   K           D       SNE    +CWNG
Sbjct:   60 CP--QEYTCCTTEMEDKLSQQSKLEFENLVEETSHFVRTTFVSRHKKFDEFFRELLENAEKSLNDMFVRTYGMLYMQNSEVFQDLFTELKRYYTGGNVNLEEMLNDFWARLLERMFQLINPQYHFSEDYLECVSKYTDQLKPFGDVPRKLKIQVTRAFIAARTFVQGLTVGRE-VANRVSKVSPTPGCIRALMKMLYCPYCRGLPTVRPCNNYCLNVMKGC-----LANQADLDTEWNLFIDAMLLVAERLEGPFNIESVMDPIDVKISEAIMNMQENSMQVSAKVFQGCGQPKPAPALRSARSAPENF------------------NTRFRPYNPEERPTTAAGTSLDRLVTDIKEKLKLSKKVWSALPYTICKDESVTAGTSNEE---ECWNG 425
[Close]
BLAST of Glypican-1 vs. UniProt/SwissProt
Match: sp|Q9R087|GPC6_MOUSE (Glypican-6 OS=Mus musculus OX=10090 GN=Gpc6 PE=1 SV=1)

HSP 1 Score: 121.324 bits (303), Expect = 3.966e-27
Identity = 93/395 (23.54%), Postives = 168/395 (42.53%), Query Frame = 2 
Query:  245 CPILQTRNCCNSVILKEMSSVSEIKLKGFAEEKLENLLTMFSNDSYILMNMYLNDLENTKNDLNQLFSATYGYNYKVEKNFFFSWFDKLKMYMEGKKHNIGQLLDEFFLEMAGKIVKILIPP-ESSPEVTKCQIDRLIEAKPYQEADNSLKKNIIRSYAPSRMFVNAIAVGRDGFRALMNKITPSSNCVAQFNTQFHCMLCNGL-TVKTCPVSCKSVMENCFGSFKLAELKKLDKIFTKYLSALFELANKLDNQLNFPAVNHKMNVQISTAIMNIQNIYPTIKEQIKAKCQN--TGSKVRRKRQVAKEFVAWQTKLGDESPFWKKKLNDNLKSGVSKKTPVGSQNTKLNDFLSPMSRRIKTKYKALEGYFLRGVHDFCTLNSQSNESSSTQCWNG 1417
            CP  Q   CC + +  ++S  S+++ +   EE    + T F +        +   LEN +  LN +F  TYG  Y      F   F +LK Y  G   N+ ++L++F+  +  ++ +++ P    S +  +C      + KP+ +    LK  + R++  +R FV  + VGR+     ++K++P+  C+       +C  C GL TV+ C   C +VM+ C     LA    LD  +  ++ A+  +A +L+   N  +V   ++V+IS AIMN+Q     +  ++   C        +R  R   + F                  N   +    ++ P  +  T L+  ++ +  ++K   K           D       SNE    +CWNG
Sbjct:   60 CP--QEYTCCTTEMEDKLSQQSKLEFENLVEETSHFVRTTFVSRHKKFDEFFRELLENAEKSLNDMFVRTYGMLYMQNSEVFQDLFTELKRYYTGGNVNLEEMLNDFWARLLERMFQLINPQYHFSEDYLECVSKYTDQLKPFGDVPRKLKIQVTRAFIAARTFVQGLTVGRE-VANRVSKVSPTPGCIRALMKMLYCPYCRGLPTVRPCNNYCLNVMKGC-----LANQADLDTEWNLFIDAMLLVAERLEGPFNIESVMDPIDVKISEAIMNMQENSMQVSAKVFQGCGQPKPAPALRSARSAPENF------------------NTRFRPYNPEERPTTAAGTSLDRLVTDIKEKLKLSKKVWSALPYTICKDERVTAGTSNEE---ECWNG 425
[Close]
BLAST of Glypican-1 vs. UniProt/SwissProt
Match: sp|Q5RE54|GPC6_PONAB (Glypican-6 OS=Pongo abelii OX=9601 GN=GPC6 PE=2 SV=1)

HSP 1 Score: 121.324 bits (303), Expect = 4.261e-27
Identity = 93/395 (23.54%), Postives = 168/395 (42.53%), Query Frame = 2 
Query:  245 CPILQTRNCCNSVILKEMSSVSEIKLKGFAEEKLENLLTMFSNDSYILMNMYLNDLENTKNDLNQLFSATYGYNYKVEKNFFFSWFDKLKMYMEGKKHNIGQLLDEFFLEMAGKIVKILIPP-ESSPEVTKCQIDRLIEAKPYQEADNSLKKNIIRSYAPSRMFVNAIAVGRDGFRALMNKITPSSNCVAQFNTQFHCMLCNGL-TVKTCPVSCKSVMENCFGSFKLAELKKLDKIFTKYLSALFELANKLDNQLNFPAVNHKMNVQISTAIMNIQNIYPTIKEQIKAKCQN--TGSKVRRKRQVAKEFVAWQTKLGDESPFWKKKLNDNLKSGVSKKTPVGSQNTKLNDFLSPMSRRIKTKYKALEGYFLRGVHDFCTLNSQSNESSSTQCWNG 1417
            CP  Q   CC + +  ++S  S+++ +   EE    + T F +        +   LEN +  LN +F  TYG  Y      F   F +LK Y  G   N+ ++L++F+  +  ++ +++ P    S +  +C      + KP+ +    LK  + R++  +R FV  + VGR+     ++K++P+  C+       +C  C GL TV+ C   C +VM+ C     LA    LD  +  ++ A+  +A +L+   N  +V   ++V+IS AIMN+Q     +  ++   C        +R  R   + F                  N   +    ++ P  +  T L+  ++ +  ++K   K           D       SNE    +CWNG
Sbjct:   60 CP--QEYTCCTTEMEDKLSQQSKLEFENLVEETSHFVRTTFVSRHKKFDEFFRELLENAEKSLNDMFVRTYGMLYMQNSEVFQDLFTELKRYYTGGNVNLEEMLNDFWARLLERMFQLINPQYHFSEDYLECVSKYTDQLKPFGDVPRKLKIQVTRAFIAARTFVQGLTVGRE-VANRVSKVSPTPGCIRALMKMLYCPYCRGLPTVRPCNNYCLNVMKGC-----LANQADLDTEWNLFIDAMLLVAERLEGPFNIESVMDPIDVKISEAIMNMQENSMQVSAKVFQGCGQPKPAPALRSARSAPENF------------------NTRFRPYNPEERPTTAAGTSLDRLVTDIKEKLKLSKKVWSSLPYTICKDESMTAGTSNEE---ECWNG 425
[Close]
BLAST of Glypican-1 vs. UniProt/SwissProt
Match: sp|P51655|GPC4_MOUSE (Glypican-4 OS=Mus musculus OX=10090 GN=Gpc4 PE=1 SV=2)

HSP 1 Score: 108.227 bits (269), Expect = 6.136e-23
Identity = 73/290 (25.17%), Postives = 136/290 (46.90%), Query Frame = 2 
Query:  245 CPILQTRNCCNSVILKEMSSVSEIKLKGFAEEKLENLLTMFSNDSYILMNMYLNDLENTKNDLNQLFSATYGYNYKVEKNFFFSWFDKLKMYMEGKKHNIGQLLDEFFLEMAGKIVKILIPP-ESSPEVTKCQIDRLIEAKPYQEADNSLKKNIIRSYAPSRMFVNAIAVGRDGFRALMNKITPSSNCVAQFNTQFHCMLCNGL-TVKTCPVSCKSVMENCFGSFKLAELKKLDKIFTKYLSALFELANKLDNQLNFPAVNHKMNVQISTAIMNIQNIYPTIKEQIKAKC 1108
            CP  Q   CC+  + ++ S  S+   K    E+  +L  +F++        +   LEN +  LN +F  TYG+ Y      F   F +LK Y      N+ ++L++F+  +  ++ +++      + E  +C      + KP+ +    LK  + R++  +R F   +AV RD   + ++ + P++ C        +C  C GL TVK C   C ++M  C     LA    LD  +  ++ A+  +A +L+   N  +V   ++V+IS AIMN+Q+    + +++   C
Sbjct:   60 CP--QDYTCCSQEMEEKYSLQSKDDFKTVVSEQCNHLQAIFASRYKKFDEFFKELLENAEKSLNDMFVKTYGHLYMQNSELFKDLFVELKRYYVAGNVNLEEMLNDFWARLLERMFRLVNSQYHFTDEYLECVSKYTEQLKPFGDVPRKLKLQVTRAFVAARTFAQGLAVARD-VVSKVSVVNPTAQCTHALLKMIYCSHCRGLVTVKPCYNYCSNIMRGC-----LANQGDLDFEWNNFIDAMLMVAERLEGPFNIESVMDPIDVKISDAIMNMQDNSVQVSQKVFQGC 341
[Close]
BLAST of Glypican-1 vs. UniProt/SwissProt
Match: sp|O75487|GPC4_HUMAN (Glypican-4 OS=Homo sapiens OX=9606 GN=GPC4 PE=1 SV=4)

HSP 1 Score: 104.76 bits (260), Expect = 9.764e-22
Identity = 72/290 (24.83%), Postives = 135/290 (46.55%), Query Frame = 2 
Query:  245 CPILQTRNCCNSVILKEMSSVSEIKLKGFAEEKLENLLTMFSNDSYILMNMYLNDLENTKNDLNQLFSATYGYNYKVEKNFFFSWFDKLKMYMEGKKHNIGQLLDEFFLEMAGKIVKILIPP-ESSPEVTKCQIDRLIEAKPYQEADNSLKKNIIRSYAPSRMFVNAIAVGRDGFRALMNKITPSSNCVAQFNTQFHCMLCNGL-TVKTCPVSCKSVMENCFGSFKLAELKKLDKIFTKYLSALFELANKLDNQLNFPAVNHKMNVQISTAIMNIQNIYPTIKEQIKAKC 1108
            CP  Q   CC+  + ++ S  S+   K    E+  +L  +F++        +   LEN +  LN +F  TYG+ Y      F   F +LK Y      N+ ++L++F+  +  ++ +++      + E  +C      + KP+ +    LK  + R++  +R F   +AV  D   + ++ + P++ C        +C  C GL TVK C   C ++M  C     LA    LD  +  ++ A+  +A +L+   N  +V   ++V+IS AIMN+Q+    + +++   C
Sbjct:   60 CP--QGSTCCSQEMEEKYSLQSKDDFKSVVSEQCNHLQAVFASRYKKFDEFFKELLENAEKSLNDMFVKTYGHLYMQNSELFKDLFVELKRYYVVGNVNLEEMLNDFWARLLERMFRLVNSQYHFTDEYLECVSKYTEQLKPFGDVPRKLKLQVTRAFVAARTFAQGLAVAGD-VVSKVSVVNPTAQCTHALLKMIYCSHCRGLVTVKPCYNYCSNIMRGC-----LANQGDLDFEWNNFIDAMLMVAERLEGPFNIESVMDPIDVKISDAIMNMQDNSVQVSQKVFQGC 341
[Close]
BLAST of Glypican-1 vs. TrEMBL
Match: I1ZI58 (Glypican-1 OS=Schmidtea mediterranea OX=79327 PE=2 SV=1)

HSP 1 Score: 247.669 bits (631), Expect = 1.600e-65
Identity = 187/646 (28.95%), Postives = 310/646 (47.99%), Query Frame = 2 
Query:   98 FIHLFFILLKFSYSTSSDECTKSTPMWYSLKYPYLNLLENYKLQNTA-FNCPILQTRNCCNSVILKEMSSVSEIKLKGFAEEKLENLLTMFSNDSYILMNMYLNDLENTKNDLNQLFSATYGYNYKVEKNFFFSWFDKLKMYMEGKKHNIGQLLDEFFLEMAGKIVKILIPPESSPEVTKCQIDRLIEAKPYQEADNSLKKNIIRSYAPSRMFVNAIAVGRDGFRALMNKITPSSNCVAQFNTQFHCMLCNGLTVKTCPVSCKSVMENCFGSFKLAELKKLDKIFTKYLSALFELANKLDNQLNFPAVNHKMNVQISTAIMNIQNIYPTIKEQIKAKCQNTGSKVRRKRQVAKEFVAWQTKLGDESPFWK---KKLNDNLKSGVSKKTPVGSQNTKLNDFLSPMSRRIKTKYKALEGYFLRGVHDFCTLNSQSNESSSTQCWNGTLPGIVT-----XXXXXXXXXXXXXXXXXTVTNNLKDITMKINDLLRDKVPDPETVAV---------EDYLLYKSKPSSKRTG---------------KPIKPTLAP------SIEGSGDFEN-----------FPISPGEQTKKIEPEEVKPTLPPPNAGKPILEEDNNQNNKIPEQPKISHNPSWEGSG--DTSENKPDT 1879
             I + F L +   + +  +C      WYS KY Y + L  +    T    CP      CC++ +  E+  VS++KLK  AE  L++++ +  N+S  L + Y N+L+ +K+ +N++F +TY  +YK  + F F ++DKLK+YM+GK+ NI ++LD FF EMA KI+++ I  +++ E  +C  +  ++  PYQ  D ++  N   +Y  +RM VN++    D F  L  K+ PS  C  ++   F+C  C+      C   CKS++  CFGSF   E+ K++K +   L AL +++NK  +  NF  VN+ ++++IS A+MN+ N Y +I+++++A C+N   K+ RKR+ ++E          ES +++   K L       +S+  P+      LND ++ +  ++K     L+ Y          L  Q N     QCWNG    I T      K      +     + KT    L+ IT  +N++L  +V DP+   +         E   L  S+ S +  G               KP  PT+ P       IEGSG+ +            FP  P       +P ++  + P P+      +++ N+N K P +P     P  EGSG  DT E   +T
Sbjct:   10 IITVLFALFENQNAQNDVDCQAIKTRWYSHKYQYSDDLLKFTTSKTVDVICP---KTTCCDNAMKTEILGVSQMKLKSIAEIHLKSIIELLYNNSRDLNDFYQNNLDISKDQMNKMFLSTYASSYKDNQRFLFDFYDKLKLYMDGKEQNIEKILDTFFTEMAEKILRMSILSKNNAEKIRCLTNSFLKLNPYQNVDKAIVSNFKEAYPTARMLVNSLRAAHDVFLDLSQKLMPSIECTTKYAKAFYCSWCSLTETMPCDGLCKSIIGKCFGSFNRKEMNKINKAWKALLGALEKISNKAKHPFNFVEVNNNLHLKISEAVMNVHNFYTSIRDKLQANCEN---KLIRKRRNSEE--------ESESQYFESVPKTLE------ISQPKPI-----LLNDLVNKLLTKMKDMTLHLQNYKNAICSSTFKLPKQGN-----QCWNGA--EITTGYKPNVKEKDANKNLKISPLVKTSIATLQKITAALNNILSKQVVDPDAFKIKFVEKPKITEIPRLRPSRISEQMEGSGKGGVDIENTSNKSKPKLPTIEPINEPKEIIEGSGEIKTPSNEISKNRPAFPQLPPNNINTPKPGKITKSPPIPDDEDLPTDQNENKNEKTP-KPAEPRTPQIEGSGSLDTVEKSTET 622
[Close]
BLAST of Glypican-1 vs. TrEMBL
Match: A0A4Z2DX73 (Glypican-4 OS=Schistosoma japonicum OX=6182 GN=EWB00_002916 PE=3 SV=1)

HSP 1 Score: 174.481 bits (441), Expect = 2.140e-40
Identity = 132/525 (25.14%), Postives = 224/525 (42.67%), Query Frame = 2 
Query:  110 FFILLKFSYSTSSDECTKSTPMWYSLKYPYLNLLENYKLQNTAFN-CPILQTRNCCNSVILKEMSSVSEIKLKGFAEEKLENLLTMFSNDSYILMNMYLNDLENTKNDLNQLFSATYGYNYKVEKNFFFSWFDKLKMYMEGKKHNIGQLLDEFFLEMAGKIVKILI--------PP------------------ESSPEVT-----KCQIDRLIEAKPYQEADNSLKKNIIRSYAPSRMFVNAIAVGRDGFRALMNKITPSSNCVAQFNTQFHCMLCNGLTVK-TCPVSCKSVMENCFGSFKLAELKKLDKIFTKYLSALFELANKLDNQLNFPAVNHKMNVQISTAIMNIQNIYPTIKEQIKAKCQ--NTG---------------------------------------SKVRRKRQVAKEFVAWQ--TKLGDESPFWKKKLNDNLKSGVSKKTPVGSQNTKLNDFLSP------MSRRIKTKYKALEGYFLRGVHDFCTLNSQS-----NESS---STQCWN 1414
              +++    ST + +CT     W  ++Y  L  L +  +     N CP+  T +CC+  + +EM SV + +L       L+    M SNDS IL +++  DL+  K  L+Q FS  YGYNYK+ +NFFF +F  L+ YM G++  +G L+  FF ++   IV ++         PP                  E + E +     +C  D++ +  P+ + D  L   ++ +Y P+RM VN ++V       L++++   S C+        C LC   ++   CP SC  ++ +C       E  +L  I+ + +  +    N+L+   NFPAVN  + ++IS AI ++Q  Y   K + +++C+  + G                                       S++ R   V++EF+ WQ   +L        + L  N    ++ KT  G   +   + ++P          IK  Y +L   F   V + C  NS +     N SS   S  CWN
Sbjct:   13 ILLIMTLVTSTYALDCTSFKQQWMKIRYTMLKGLHSSTINGPTSNICPVTGT-SCCDVNMEREMYSVGQRQLIKQCNSWLQVARKM-SNDSAILESIFQADLQQAKGRLHQFFSRIYGYNYKLHRNFFFGFFTDLEQYMAGQRGQLGVLIKNFFNQLRDSIVSLIEKSGQVISNPPFGSAPSNAGSFGNNSPGIEGTDEASESRRIRCLSDKIAQLHPFDDVDVRLHARMLEAYPPARMLVNVLSVTSKLLHHLVDQVVAQSQCILGITRYRFCALCEAQSLSNVCPDSCAQLLSSCLHGDGPDE-AQLAYIWPQLIDTIVVATNRLERSFNFPAVNRNLQMEISEAITSLQTRYSETKSKFESECRFGSAGRRMPTLFNPIGPTHNNQENFANLSNISRWPRISNLNRRLSRIARSSPVSQEFLDWQGRQRLSKAISGSNRPLKINYGQQMTSKTSHGWDASDKENPVNPPHDLVRQVNEIKQAYSSLRNMFSGPVGNLCQSNSTTMSRNENLSSGNLSGHCWN 534
[Close]
BLAST of Glypican-1 vs. TrEMBL
Match: C1LFG9 (Glypican-4 OS=Schistosoma japonicum OX=6182 GN=Xgly4 PE=2 SV=1)

HSP 1 Score: 174.096 bits (440), Expect = 2.566e-40
Identity = 133/525 (25.33%), Postives = 227/525 (43.24%), Query Frame = 2 
Query:  110 FFILLKFSYSTSSDECTKSTPMWYSLKYPYLNLLENYKLQNTAFN-CPILQTRNCCNSVILKEMSSVSEIKLKGFAEEKLENLLTMFSNDSYILMNMYLNDLENTKNDLNQLFSATYGYNYKVEKNFFFSWFDKLKMYMEGKKHNIGQLLDEFFLEMAGKIVKILI--------PP------------------ESSPEVT-----KCQIDRLIEAKPYQEADNSLKKNIIRSYAPSRMFVNAIAVGRDGFRALMNKITPSSNCVAQFNTQFHCMLCNGLTVK-TCPVSCKSVMENCFGSFKLAELKKLDKIFTKYLSALFELANKLDNQLNFPAVNHKMNVQISTAIMNIQNIYPTIKEQIKAKCQ--NTG---------------------------------------SKVRRKRQVAKEFVAWQ--TKLGDESPFWKKKLNDNLKSGVSKKTPVGSQNTKLNDFLSP---MSRR---IKTKYKALEGYFLRGVHDFCTLNSQS-----NESS---STQCWN 1414
              +++    ST + +CT     W  ++Y  L  L +  +     N CP+  T +CC+  + +EM SV + +L       L+    M SNDS IL +++  DL+  K  L+Q FS  YGYNYK+ +NFFF +F  L+ YM G++  +G L+  FF ++   IV ++         PP                  E + E +     +C  D++ +  P+ + D  L   ++ +Y P+RM VN ++V       L++++   S C+        C LC   ++   CP SC  ++ +C       E  +L  I+ + +  +    N+L+   NFPAVN  + ++IS AI ++Q  Y   K + +++C+  + G                                       S++ R   V++EF+ WQ   +L        + L  N    ++ KT  G   +   + ++P   + R+   IK  Y +L   F   V + C  NS +     N SS   S  CWN
Sbjct:   13 ILLIMTLVTSTYALDCTSFKQQWMKIRYTMLKGLHSSTINGPTSNICPVTGT-SCCDVNMEREMYSVGQRQLIKQCNSWLQVARKM-SNDSAILESIFQADLQQAKGRLHQFFSRIYGYNYKLHRNFFFGFFTDLEQYMAGQRGQLGVLIKNFFNQLRDSIVSLIEKSGQVISNPPFGSAPSNAGSFGNNSPGIEGTDEASESRRIRCLSDKIAQLHPFDDVDVRLHARMLEAYPPARMLVNVLSVTSKLLHHLVDQVVAQSQCILGITRYRFCALCEAQSLSNVCPDSCAQLLSSCLHGDGPDE-AQLAYIWPQLIDTIVVATNRLERSFNFPAVNRNLQMEISEAITSLQTRYSETKSKFESECRFGSAGRRMPTLFNPIGPTHNNQENFANLSNISRWPRISNLNRRLSRIARSSPVSQEFLDWQGRQRLSKAISGSNRPLKINYGQQMTSKTSHGWDASDKENPVNPPHDLVRQVNEIKQAYSSLRNMFSGPVGNLCQSNSTTMSRNENLSSGNLSGHCWN 534
[Close]
BLAST of Glypican-1 vs. TrEMBL
Match: A0A183MKF2 (Uncharacterized protein OS=Schistosoma margrebowiei OX=48269 GN=SMRZ_LOCUS16527 PE=3 SV=1)

HSP 1 Score: 166.392 bits (420), Expect = 6.716e-38
Identity = 108/384 (28.12%), Postives = 182/384 (47.40%), Query Frame = 2 
Query:   83 MNFNAFIHLFFILLKFSYSTSSDECTKSTPMWYSLKYPYLNLLENYKLQNTAFN-CPILQTRNCCNSVILKEMSSVSEIKLKGFAEEKLENLLTMFSNDSYILMNMYLNDLENTKNDLNQLFSATYGYNYKVEKNFFFSWFDKLKMYMEGKKHNIGQLLDEFFLEMAGKIVKILI--------PPESS------------PEV-----------TKCQIDRLIEAKPYQEADNSLKKNIIRSYAPSRMFVNAIAVGRDGFRALMNKITPSSNCVAQFNTQFHCMLCNGLTV-KTCPVSCKSVMENCFGSFKLAELKKLDKIFTKYLSALFELANKLDNQLNFPAVNHKMNVQISTAIMNIQNIYPTIKEQIKAKCQNTGSKVRR 1135
            M  +  I L   L   +Y+    +CT     W  L+Y  L  + +  +   A N CP+  T +CC+  +  EM SV + +L       L+    M SNDS +L +++  DL+  K  L+Q FS  YGYNYK+ +NFFF +F  L+ YM G++  +G L+  FF ++   IV ++         PP SS            P V            +C  +++ +  P+ + D  L   ++ +Y P+RM VN ++V       L++++   S C+        C +C   ++   CP SC  ++  C       E  +L+ I+ + +  +    N+L+   NFPAVN  + ++IS AI ++Q  Y   K + +++C+  GS  RR
Sbjct:    7 MRTSGSILLIVTLCTSAYAL---DCTTFKQEWMKLRYTILTGVHSSAIIGPASNICPVTGT-SCCDVSMEHEMYSVGQRQLIKQTNSWLQVAWKM-SNDSAVLESIFQADLQQAKGRLHQFFSRIYGYNYKLHRNFFFGFFTDLEQYMAGQRGQLGVLIKNFFSQLRDSIVSLIEKSGQVNSNPPFSSVSPNTGSFGNSLPGVGGTDEASESRRIRCLSEKIAQLHPFDDVDVRLHARMLEAYPPARMLVNVLSVTSKLLHYLVDQVVTQSQCILGITRYRFCAICEAQSLNNVCPESCSQLLAGCLHGDGPDE-AQLEYIWPQLIDTIIMATNRLERSFNFPAVNRNLQMEISEAITSLQTRYSETKSKFESECR-FGSAGRR 383
[Close]
BLAST of Glypican-1 vs. TrEMBL
Match: A0A094ZZE7 (Glypican-6 OS=Schistosoma haematobium OX=6185 GN=MS3_08283 PE=3 SV=1)

HSP 1 Score: 159.844 bits (403), Expect = 1.709e-37
Identity = 103/375 (27.47%), Postives = 176/375 (46.93%), Query Frame = 2 
Query:  116 ILLKFSYSTSSD--ECTKSTPMWYSLKYPYLNLLENYKLQNTAFN-CPILQTRNCCNSVILKEMSSVSEIKLKGFAEEKLENLLTMFSNDSYILMNMYLNDLENTKNDLNQLFSATYGYNYKVEKNFFFSWFDKLKMYMEGKKHNIGQLLDEFFLEMAGKIVKIL-------------------------IP------PESSPEVTKCQIDRLIEAKPYQEADNSLKKNIIRSYAPSRMFVNAIAVGRDGFRALMNKITPSSNCVAQFNTQFHCMLCNGLTV-KTCPVSCKSVMENCFGSFKLAELKKLDKIFTKYLSALFELANKLDNQLNFPAVNHKMNVQISTAIMNIQNIYPTIKEQIKAKCQNTGSKVRR 1135
            ILL  +  TS+   +CT     W  L+Y  L  + +  +     N CP+  T +CC+  +  EM SV + +L       L+    M SNDS +L +++  DL+  K  L+Q FS  YGYNYK+ KNFFF +F  L+ YM G++  +G L+  FF ++   IV ++                         +P        S     +C  +++ +  P+ + D  L   ++ +Y P+RM VN ++V       L++++   S C+        C +C   ++   CP SC  ++  C       +  +L  I+ + +  +    N+L+   NFPAVN  + ++IS AI ++Q  Y   K + +++C+  GS  RR
Sbjct:   13 ILLIVTLCTSAYALDCTTFKQEWMKLRYTILTGVHSSTIIGPTSNICPVTGT-SCCDVSMEHEMYSVGQRQLIKQTNSWLQVAWKM-SNDSAVLESIFQADLKQAKGRLHQFFSRIYGYNYKLHKNFFFGFFTDLEQYMAGQQGQLGVLIKNFFSQLRDSIVSLIEKSGQVNSSPPFSSISPNTGSFGNSLPGVGGTDEASESRRIRCLSEKIAQLHPFDDVDVRLHARMLEAYPPARMLVNVLSVTSKLLHYLVDQVVAQSQCILGITRYRFCAICEAQSLNNVCPESCSQLLAGCL-HVDGPDETQLAYIWPQLIDTIIMATNRLERSFNFPAVNRNLQMEISEAITSLQTRYSETKSKFESECR-FGSAGRR 383
[Close]
BLAST of Glypican-1 vs. Ensembl Cavefish
Match: gpc6b (glypican 6b [Source:ZFIN;Acc:ZDB-GENE-130515-2])

HSP 1 Score: 118.627 bits (296), Expect = 3.174e-27
Identity = 101/397 (25.44%), Postives = 174/397 (43.83%), Query Frame = 2 
Query:  254 LQTRNCCNSVILKEMSSVSEIKLKGFAEEKLENLLTMFSNDSYILMNMYLNDLENTKNDLNQLFSATYGYNYKVEKNFFFSWFDKLKMYMEGKKHNIGQLLDEFFLEMAGKIVKILIPPESSPEVTKCQIDRLIEAKPYQEADNSLKKNIIRSYAPSRMFVNAIAVGRDGFRALMNKITPSSNCVAQFNTQFHCMLCNGLT-VKTCPVSCKSVMENCFGSFKLAELKKLDKIFTKYLSALFELANKLDNQLNFPAVNHKMNVQISTAIMNIQNIYPTIKEQIKAKC---QNTGSKVRRKRQVAKEFVAWQTKLGDESPFWKKKLNDNLKSGVSKKTPVGSQNTKLNDFLSPMSRRIKTKYKALEGYFLRGVHDFCTLNSQSNESSSTQ-CWNGTLPG 1429
            +Q R CC   + ++++  S+ + +   +E  E+L   F +        +L  LENT+  LN++F  TYG  Y      F   F +LK Y  G+   + QLL+  +L               + E  +C    + + KP+ +    LK  + R++  +R FV  + VGR+     ++K++ S  CV       +C  C GLT +K C   C +V++ C     LA    LD  +T Y+ A+  +  +L+   N  +V   ++V+IS AIMN+Q+    +  Q+   C   +++G+  R  R V+  F       G   P+  ++L            P  +  T L+  +      IK K +  + ++       C     S E+  T+ CWNG   G
Sbjct:   56 VQERTCCTLEVEEKLTERSKHEFEKLMDEATEDLRDTFVSRHKRFDEFFLELLENTERSLNEMFVRTYGKPYMQNAEVFQGLFSELKRYYTGR---MFQLLNSQYL--------------ITEEYLECISKYMDQLKPFGDVPKKLKSQVTRAFIAARTFVQGLMVGRE-VANRVSKVSISVACVKAVTRMLYCPSCRGLTAIKPCRTYCLNVLKGC-----LANQADLDPEWTHYIDAMLLVTERLEGPFNIESVMEPIDVKISEAIMNMQDKSVQLSYQVFQGCGQPKSSGTS-RSARGVSDVFS------GRFRPYNPEEL------------PTSAAGTSLDRLVID----IKDKLRHSKNFWSSLPEGICEGEHVSTETEETEDCWNGQEMG 406
[Close]
BLAST of Glypican-1 vs. Ensembl Cavefish
Match: gpc6b (glypican 6b [Source:ZFIN;Acc:ZDB-GENE-130515-2])

HSP 1 Score: 116.316 bits (290), Expect = 1.415e-26
Identity = 101/400 (25.25%), Postives = 174/400 (43.50%), Query Frame = 2 
Query:  254 LQTRNCCNSVILKEMSSVSEIKLKGFAEEKLENLLTMFSNDSYILMNMYLNDLENTKNDLNQLFSATYGYNYKVEKNFFFSWFDKLKMYMEGKKHNIGQLLDEFFLEMAGKIVKILIPPESSPEVTKCQIDRLIEAKPYQEADNSLKKNIIRSYAPSRMFVNAIAVGRDGFRALMNKITPSSNCVAQFNTQFHCMLCNGLT-VKTCPVSCKSVMENCFGSFKLAELKKLDKIFTKYLSALFELANKLDNQLNFPAVNHKMNVQISTAIMNIQNIYPTIKEQIKAKC---QNTGSKVRRKRQVAKEFVAWQTKLGDESPFWKKKLNDNLKSGVSKKTPVGSQNTKLNDFLSPMSRR---IKTKYKALEGYFLRGVHDFCTLNSQSNESSSTQ-CWNGTLPG 1429
            +Q R CC   + ++++  S+ + +   +E  E+L   F +        +L  LENT+  LN++F  TYG  Y      F   F +LK Y  G+   + QLL+  +L               + E  +C    + + KP+ +    LK  + R++  +R FV  + VGR+     ++K++ S  CV       +C  C GLT +K C   C +V++ C     LA    LD  +T Y+ A+  +  +L+   N  +V   ++V+IS AIMN+Q+    +  Q+   C   +++G+  R  R V+  F       G   P+  ++L           +  G+   +L      M      IK K +  + ++       C     S E+  T+ CWNG   G
Sbjct:   39 VQERTCCTLEVEEKLTERSKHEFEKLMDEATEDLRDTFVSRHKRFDEFFLELLENTERSLNEMFVRTYGKPYMQNAEVFQGLFSELKRYYTGR---MFQLLNSQYL--------------ITEEYLECISKYMDQLKPFGDVPKKLKSQVTRAFIAARTFVQGLMVGRE-VANRVSKVSISVACVKAVTRMLYCPSCRGLTAIKPCRTYCLNVLKGC-----LANQADLDPEWTHYIDAMLLVTERLEGPFNIESVMEPIDVKISEAIMNMQDKSVQLSYQVFQGCGQPKSSGTS-RSARGVSDVFS------GRFRPYNPEEL---------PTSAAGTSLDRLRIVWKTMQHSVIDIKDKLRHSKNFWSSLPEGICEGEHVSTETEETEDCWNGQEMG 399
[Close]
BLAST of Glypican-1 vs. Ensembl Cavefish
Match: gpc6a (glypican 6a [Source:ZFIN;Acc:ZDB-GENE-071004-15])

HSP 1 Score: 114.005 bits (284), Expect = 8.460e-26
Identity = 72/271 (26.57%), Postives = 134/271 (49.45%), Query Frame = 2 
Query:  263 RNCCNSVILKEMSSVSEIKLKGFAEEKLENLLTMFSNDSYILMNMYLNDLENTKNDLNQLFSATYGYNYKVEKNFFFSWFDKLKMYMEGKKHNIGQLLDEFFLEMAGKIVKILIPPES-SPEVTKCQIDRLIEAKPYQEADNSLKKNIIRSYAPSRMFVNAIAVGRDGFRALMNKITPSSNCVAQFNTQFHCMLCNGL-TVKTCPVSCKSVMENCFGSFKLAELKKLDKIFTKYLSALFELANKLDNQLNFPAVNHKMNVQISTAIMNIQN 1069
            + CC+S +  ++   S++KL+G  EE  + L + F +        +L  L+N++  LN +F  TYG  Y      F   F +LK Y  G   N+ ++L++F+  +  ++ ++L    + + +  +C      + KP+ +    LK  + R++  +R FV  + VGR+     ++K+  S  C        +C  C GL  ++ C   C++VM+ C     LA    LD  +  ++ A+  +A +L+   N  AV   ++V+IS AIM +Q+
Sbjct:   37 QTCCSSEMEDKLGVQSKVKLEGMVEESSDVLRSTFFSRHKKFDEFFLELLDNSEKSLNDMFVRTYGKLYTHNSEIFEDLFSELKRYYTGGNVNLEEMLNDFWSRLLERMFQLLNSQYTFTDDYLECISKYTDQLKPFGDIPRKLKAQVTRAFIAARTFVQGLMVGRE-VANRVSKVNVSPGCSKALTRMLYCPYCGGLPGLRPCGNYCQNVMKGC-----LANQADLDPEWNLFIDAMLLVAERLEGPFNIEAVMEPIDVKISEAIMTMQD 301
[Close]
BLAST of Glypican-1 vs. Ensembl Cavefish
Match: gpc4 (glypican-4 [Source:NCBI gene;Acc:103025650])

HSP 1 Score: 102.834 bits (255), Expect = 3.952e-22
Identity = 81/326 (24.85%), Postives = 146/326 (44.79%), Query Frame = 2 
Query:  179 YSLKYPYLNLLENYKLQNTAFN-CPILQTRNCCNSVILKEMSSVSEIKLKGFAEEKLENLLTMFSNDSYILMNMYLNDLENTKNDLNQLFSATYGYNYKVEKNFFFSWFDKLKMYME--GKKHNIGQLLDEFFLEMAGKIVKIL-IPPESSPEVTKCQIDRLIEAKPYQEADNSLKKNIIRSYAPSRMFVNAIAVGRDGFRALMNKITPSSNCVAQFNTQFHCMLCNG-LTVKTCPVSCKSVMENCFGSFKLAELKKLDKIFTKYLSALFELANKLDNQLNFPAVNHKMNVQISTAIMNIQNIYPTIKEQIKAKCQNTGSKVRRKR 1141
            YS K   +N + N  +Q      CP  Q  +CC   + +++S  S   LK    +    L + F+         +   L N +  L+ +F  TYG  Y      F  +F +L+ Y    G   ++  +L EF+ E+  ++ +++ +  E +    +C      + KP+ +    LK  + R++  +R F   +A+  D   + ++ ++ S +CV       +C  C+G + +K C   C +VM  C     LA    LD  +  +L A+  LA +L+   NF +V   ++V+IS AIMN+Q     + +++   C       R KR
Sbjct:   36 YSSKGFNINDVPNKGVQGAHLKVCP--QGFSCCTLEMEEKLSQQSRTDLKAPVSQLSSTLQSTFTQRHQHFDQFFKELLTNAEKSLHDMFVRTYGVMYVKNAELFKHFFHELRRYYASGGAAVHLDSMLSEFWAELLERMFRLVNVQYEFTDGYMECVSRHTDQLKPFGDVPRKLKLQLTRAFVAARTFTLGLALIPD-VVSKVSTVSASPSCVRAAMKMLYCPYCSGQVALKPCKNYCLNVMRGC-----LANQADLDTEWNNFLDAMLSLAERLEGPFNFESVMDPIDVKISDAIMNMQENSMQVSQKVFQGCGQPKPMYRSKR 353
[Close]
BLAST of Glypican-1 vs. Ensembl Cavefish
Match: gpc1a (glypican 1a [Source:NCBI gene;Acc:553367])

HSP 1 Score: 93.9745 bits (232), Expect = 2.635e-19
Identity = 97/447 (21.70%), Postives = 189/447 (42.28%), Query Frame = 2 
Query:  101 IHLFFILLKFSYSTSSDECTKSTPMWYSLKYPYLNLLENYKLQNTAFN-CPILQTRNCCNSVILKEMSSVSEIKLKGFAEEKLENLLTMFSNDSYILMNMYLNDLEN-TKNDLNQLFSATYGYNYKVEKNFFFSWFDKLKMYMEGKKHNIGQLLDEFFLEMAGKIVKILIPPESS---PEVTKCQIDRLIEAKPYQEADNSLKKNIIRSYAPSRMFVNAIAVGRDGFRALMNKITPSSNCVAQFNTQFHCMLCNGL-TVKTCPVSCKSVMENCFGSFKLAELKKLDKIFTKYLSALFELANKLDNQLNFPAVNHKMNVQISTAIMNIQNIYPTIKEQIKAKCQNTGSKVRRKRQVAKEFVAWQTKLGDESPFWKKKLNDNLKSGVS--KKTPVGSQNTKLNDFLSPMSRRIKTKYKALEGYFLRGVHDFCTLNSQSNESSSTQCWNG 1417
            + L  + +    +  +  CT+    +YS K   LN + N ++       CP  Q   CC S + + +S++S  + +G   E   ++     N  Y   + Y  +L N ++  L + F    G  Y      F   + +L+ Y  G   N+ + LDEF+  +  +++K   P  +S    +  +C   +    + + EA   LK  ++R +  +R FV  + +  D  R + +++  +  C        +C  C GL +VK C   CK+VM+ C     LA    LD  +   +  + ++A+    + +   + H + V+IS A+ ++Q        ++   C   G +               T + +E    KKK     +S V+  +  P  +   +L   +S +S    +K K ++ ++++     C   + S  S++ +CWNG
Sbjct:    8 VALCLLAVCVCAADKAKSCTE-VRHFYSGKGFTLNGVPNSEISGEHLRVCP--QGYTCCTSAMEETLSNLSRREFEGLVREAGRSIQATL-NAQYRSFDTYFIELLNGSERWLEEAFVKALGALYGPNAVVFRDLYSELRRYYRGAALNLEEALDEFWARLLERMLKASDPAAASLISDDFLECASKQAETLRLFGEAPRELKTRLVRVFVAARAFVQGLNMAGDVVRKV-SQVPLTPECNRAIMKLVYCPHCRGLGSVKPCANYCKNVMKGC-----LANQADLDTEWQNLIDTMLQVASSFGTEPSMDVILHSIPVRISEAVQHMQENMELYTNKLFQACGERGEE------------GTPTSVSEEP---KKK-----ESTVTTLEYKPSSAAAVRLEVQVSDVS----SKLKEMQMFWIQLASALCNSKAASGSSNNDKCWNG 420
[Close]
BLAST of Glypican-1 vs. Ensembl Medaka
Match: gpc2 (glypican 2 [Source:NCBI gene;Acc:101173153])

HSP 1 Score: 112.079 bits (279), Expect = 5.971e-25
Identity = 85/398 (21.36%), Postives = 172/398 (43.22%), Query Frame = 2 
Query:  245 CPILQTRNCCNSVILKEMSSVSEIKLKGFAEEKLENLLTMFSNDSYILMNMYLNDLENTKNDLNQLFSATYGYNYKVEKNFFFSWFDKLKMYMEGKKHNIGQLLDEFFLEMAGKIVKILIPP-ESSPEVTKCQIDRLIEAKPYQEADNSLKKNIIRSYAPSRMFVNAIAVGRDGFRALMNKITPSSNCVAQFNTQFHCMLCNGLT-VKTCPVSCKSVMENCFGSFKLAELKKLDKIFTKYLSALFELANKLDNQLNFPAVNHKMNVQISTAIMNIQNIYPTIKEQIKAKCQNTGSKVRRKRQVAKEFVAWQTKLGDESPFWKKKLNDNLKSGVSKKTPVGSQNTKLNDFLSPMSRRIKTKYKALEGYFLRGVHDFCTLNS-QSNESSSTQCWNGTLPG 1429
            CP  Q   CC+S + + +   SE       EE  + L T F+         +   ++ ++  +NQ+F+ TYG  +    + F   F +L+ Y  G   ++ ++L +F+  +  ++  ++ P  + S +  +C      + +P+ +    L+  + R++  +R     +A GRD       K+T    CV     Q++C LC G+  ++ C   C +VM+ C     LA    LD  +  ++ AL+ ++ KL+   N       + V++S AIM +Q    ++  ++   C        R ++  KE        G   PF         ++   ++ P  +  T L+  ++ +  R+    + + G+++      C      ++ ++S +CWNG   G
Sbjct:   68 CP--QDYTCCSSQMEETLGLQSERDFLKAIEENSQFLQTTFTQRHRRFDEFFRELIDLSEKSMNQMFTKTYGLLFTQNAHIFQELFVELRRYYSGSSVSLAEVLSDFWSRLVERVFSLVNPQYQFSEDYLECVSKHAEQLQPFGDMPRKLRVQVSRAFIAARSLSQGLATGRDIVNK-ATKLTADPECVRGLMRQWYCPLCRGVPYLQPCHPLCLNVMKGC-----LANQADLDTEWNNFIDALYLVSEKLEGPFNMELAAESIAVKVSEAIMYMQENSVSVSSKVFQGCGAPKPSPARSKRSPKE------SGGSRRPF---------RTYTPEEKPTTAAGTNLDRLVTELKERL----RPMTGFWVSLPQTICNDEKLAADVTNSERCWNGQTRG 438
[Close]
BLAST of Glypican-1 vs. Ensembl Medaka
Match: gpc2 (glypican 2 [Source:NCBI gene;Acc:101173153])

HSP 1 Score: 112.079 bits (279), Expect = 5.971e-25
Identity = 85/398 (21.36%), Postives = 172/398 (43.22%), Query Frame = 2 
Query:  245 CPILQTRNCCNSVILKEMSSVSEIKLKGFAEEKLENLLTMFSNDSYILMNMYLNDLENTKNDLNQLFSATYGYNYKVEKNFFFSWFDKLKMYMEGKKHNIGQLLDEFFLEMAGKIVKILIPP-ESSPEVTKCQIDRLIEAKPYQEADNSLKKNIIRSYAPSRMFVNAIAVGRDGFRALMNKITPSSNCVAQFNTQFHCMLCNGLT-VKTCPVSCKSVMENCFGSFKLAELKKLDKIFTKYLSALFELANKLDNQLNFPAVNHKMNVQISTAIMNIQNIYPTIKEQIKAKCQNTGSKVRRKRQVAKEFVAWQTKLGDESPFWKKKLNDNLKSGVSKKTPVGSQNTKLNDFLSPMSRRIKTKYKALEGYFLRGVHDFCTLNS-QSNESSSTQCWNGTLPG 1429
            CP  Q   CC+S + + +   SE       EE  + L T F+         +   ++ ++  +NQ+F+ TYG  +    + F   F +L+ Y  G   ++ ++L +F+  +  ++  ++ P  + S +  +C      + +P+ +    L+  + R++  +R     +A GRD       K+T    CV     Q++C LC G+  ++ C   C +VM+ C     LA    LD  +  ++ AL+ ++ KL+   N       + V++S AIM +Q    ++  ++   C        R ++  KE        G   PF         ++   ++ P  +  T L+  ++ +  R+    + + G+++      C      ++ ++S +CWNG   G
Sbjct:   68 CP--QDYTCCSSQMEETLGLQSERDFLKAIEENSQFLQTTFTQRHRRFDEFFRELIDLSEKSMNQMFTKTYGLLFTQNAHIFQELFVELRRYYSGSSVSLAEVLSDFWSRLVERVFSLVNPQYQFSEDYLECVSKHAEQLQPFGDMPRKLRVQVSRAFIAARSLSQGLATGRDIVNK-ATKLTADPECVRGLMRQWYCPLCRGVPYLQPCHPLCLNVMKGC-----LANQADLDTEWNNFIDALYLVSEKLEGPFNMELAAESIAVKVSEAIMYMQENSVSVSSKVFQGCGAPKPSPARSKRSPKE------SGGSRRPF---------RTYTPEEKPTTAAGTNLDRLVTELKERL----RPMTGFWVSLPQTICNDEKLAADVTNSERCWNGQTRG 438
[Close]
BLAST of Glypican-1 vs. Ensembl Medaka
Match: gpc6a (glypican-6 [Source:NCBI gene;Acc:101172317])

HSP 1 Score: 108.997 bits (271), Expect = 4.569e-24
Identity = 90/398 (22.61%), Postives = 176/398 (44.22%), Query Frame = 2 
Query:  245 CPILQTRNCCNSVILKEMSSVSEIKLKGFAEEKLENLLTMFSNDSYILMNMYLNDLENTKNDLNQLFSATYGYNYKVEKNFFFSWFDKLKMYMEGKKHNIGQLLDEFFLEMAGKIVKILIPP-ESSPEVTKCQIDRLIEA-KPYQEADNSLKKNIIRSYAPSRMFVNAIAVGRDGFRALMNKITPSSNCVAQFNTQFHCMLCNGLT-VKTCPVSCKSVMENCFGSFKLAELKKLDKIFTKYLSALFELANKLDNQLNFPAVNHKMNVQISTAIMNIQNIYPTIKEQIKAKCQNTGSKVRRKRQVAKEFVAWQTKLGDESPFWKKKLNDNLKSGVSKKTPVGSQNTKLNDFLSPMSRRIKTKYKALEGYFLRGVHDFCTLNSQSNESSSTQCWNGTLPG 1429
            CP  Q   CC S + ++++  S+++ +   EE    + T F +        +L  L+N++  LN LF+ TYG  Y      F   F +LK Y  G   N+ ++L++F+  +  ++ ++L      + +  +C I ++ +  KP+ +A   LK  + +++  +R FV  + VGR+     + K+  +  CV       +C  C G+  +K C   C +VM  C     LA    LD  +  ++ A+  +AN+L+   N  AV   ++++IS AI+ +Q     +  ++  +C           Q     ++  T+  D        LN   +    ++ P  +  T L   ++ +  R++   +     + +  +D C+   +  +    QCWN    G
Sbjct:   60 CP--QGYTCCTSEMEEKLNQQSKLEFENMVEESSRQMRTTFISRHKKFDEFFLELLDNSEKSLNSLFTRTYGKLYMQNSEVFQDLFTELKRYYTGGNVNLEEMLNDFWSRLLERMFQLLNSQYHFTDDYLEC-IGKIADVLKPFGDAPRRLKIQVTKAFIAARTFVQGLMVGRE-VANRVAKVNVAPACVRALTKMLYCPYCRGMAGLKPCHNYCHNVMRGC-----LANQADLDSEWNLFIDAMLLVANRLEGPDNIEAVIDPVDIKISEAIITMQENSMQVSAKVFQECG----------QPKPSGLSRSTRGID-------MLNSRFRPYTPEQRPTSAAGTSLERLVNDIKERLEESKRV----WSKLPNDICS-KEKLTQPDEEQCWNSHTKG 426
[Close]
BLAST of Glypican-1 vs. Ensembl Medaka
Match: gpc6a (glypican-6 [Source:NCBI gene;Acc:101172317])

HSP 1 Score: 107.842 bits (268), Expect = 1.253e-23
Identity = 74/291 (25.43%), Postives = 141/291 (48.45%), Query Frame = 2 
Query:  245 CPILQTRNCCNSVILKEMSSVSEIKLKGFAEEKLENLLTMFSNDSYILMNMYLNDLENTKNDLNQLFSATYGYNYKVEKNFFFSWFDKLKMYMEGKKHNIGQLLDEFFLEMAGKIVKILIPP-ESSPEVTKCQIDRLIEA-KPYQEADNSLKKNIIRSYAPSRMFVNAIAVGRDGFRALMNKITPSSNCVAQFNTQFHCMLCNGLT-VKTCPVSCKSVMENCFGSFKLAELKKLDKIFTKYLSALFELANKLDNQLNFPAVNHKMNVQISTAIMNIQNIYPTIKEQIKAKC 1108
            CP  Q   CC S + ++++  S+++ +   EE    + T F +        +L  L+N++  LN LF+ TYG  Y      F   F +LK Y  G   N+ ++L++F+  +  ++ ++L      + +  +C I ++ +  KP+ +A   LK  + +++  +R FV  + VGR+     + K+  +  CV       +C  C G+  +K C   C +VM  C     LA    LD  +  ++ A+  +AN+L+   N  AV   ++++IS AI+ +Q     +  ++  +C
Sbjct:   60 CP--QGYTCCTSEMEEKLNQQSKLEFENMVEESSRQMRTTFISRHKKFDEFFLELLDNSEKSLNSLFTRTYGKLYMQNSEVFQDLFTELKRYYTGGNVNLEEMLNDFWSRLLERMFQLLNSQYHFTDDYLEC-IGKIADVLKPFGDAPRRLKIQVTKAFIAARTFVQGLMVGRE-VANRVAKVNVAPACVRALTKMLYCPYCRGMAGLKPCHNYCHNVMRGC-----LANQADLDSEWNLFIDAMLLVANRLEGPDNIEAVIDPVDIKISEAIITMQENSMQVSAKVFQEC 341
[Close]
BLAST of Glypican-1 vs. Ensembl Medaka
Match: gpc4 (glypican-6 [Source:NCBI gene;Acc:101160491])

HSP 1 Score: 100.908 bits (250), Expect = 1.645e-21
Identity = 72/292 (24.66%), Postives = 142/292 (48.63%), Query Frame = 2 
Query:  245 CPILQTRNCCNSVILKEMSSVSEIKLKGFAEEKLENLLTMFSNDSYILMNMYLNDLENTKNDLNQLFSATYGYNYKVEKNFFFSWFDKL-KMYMEG-KKHNIGQLLDEFFLEMAGKIVKIL-IPPESSPEVTKCQIDRLIEAKPYQEADNSLKKNIIRSYAPSRMFVNAIAVGRDGFRALMNKITPSSNCVAQFNTQFHCMLCNG-LTVKTCPVSCKSVMENCFGSFKLAELKKLDKIFTKYLSALFELANKLDNQLNFPAVNHKMNVQISTAIMNIQNIYPTIKEQIKAKC 1108
            CP  Q  +CC   + +++S  S  ++K        NL T+F        N +   L+N +  L+ +F  TYG  Y+     F ++F  L + Y++G  K ++  +L +F+ ++  ++ +++ +  E S    +C      E +P+ +    L+  + R++  +R FV  + +  + F  + + ++ + +CV       +C  C+G + +K C   C +VM  C     LA    LD  +  +L A+  LA++L+   NF +V   ++V+IS AIMN+Q     + +++   C
Sbjct:   59 CP--QGFSCCTVEMEEKLSQQSHTEIKAPVSRLSTNLQTIFKERHNHFDNFFRELLKNAEASLHNMFLRTYGKMYEQNSELFGNFFASLTRYYIDGSAKVDLDAMLTDFWADLLERMFRLVNVQFEFSDAYMECVSRNTDELQPFGDVPRKLRIQLKRAFIAARTFVRGLKLMPEVFNKV-STVSATPSCVRAATKMLYCPYCSGQVALKPCQNYCLNVMRGC-----LANQADLDTEWNNFLDAMLNLADRLEGPFNFESVMDPIDVKISEAIMNMQENSMQVSQKVFQGC 342
[Close]
BLAST of Glypican-1 vs. Planmine SMEST
Match: SMESG000032627.1 (SMESG000032627.1)

HSP 1 Score: 1631.31 bits (4223), Expect = 0.000e+0
Identity = 864/865 (99.88%), Postives = 865/865 (100.00%), Query Frame = 2 
Query:   53 MIYAFLNNPKMNFNAFIHLFFILLKFSYSTSSDECTKSTPMWYSLKYPYLNLLENYKLQNTAFNCPILQTRNCCNSVILKEMSSVSEIKLKGFAEEKLENLLTMFSNDSYILMNMYLNDLENTKNDLNQLFSATYGYNYKVEKNFFFSWFDKLKMYMEGKKHNIGQLLDEFFLEMAGKIVKILIPPESSPEVTKCQIDRLIEAKPYQEADNSLKKNIIRSYAPSRMFVNAIAVGRDGFRALMNKITPSSNCVAQFNTQFHCMLCNGLTVKTCPVSCKSVMENCFGSFKLAELKKLDKIFTKYLSALFELANKLDNQLNFPAVNHKMNVQISTAIMNIQNIYPTIKEQIKAKCQNTGSKVRRKRQVAKEFVAWQTKLGDESPFWKKKLNDNLKSGVSKKTPVGSQNTKLNDFLSPMSRRIKTKYKALEGYFLRGVHDFCTLNSQSNESSSTQCWNGTLPGIVTXXXXXXXXXXXXXXXXXTVTNNLKDITMKINDLLRDKVPDPETVAVEDYLLYKSKPSSKRTGKPIKPTLAPSIEGSGDFENFPISPGEQTKKIEPEEVKPTLPPPNAGKPILEEDNNQNNKIPEQPKISHNPSWEGSGDTSENKPDTKPFNQLPVNTPEKKSSILVPRNTSTPSLVKVVIQSSTESNINTDDEDMVSRLPNIVPEKPIITSSSKPNIIPEGSGSDPDFAANKPQIPAVESITTITTTASLPDKPVEGSGSEVDPPQEVPRPVLPMIPEIQGSTIKPPSSRDSKFNPDEEKSIXXXXXXXXXXXXXXXXXXXXXXXIQRISPKPETITDYHHRQSTLSPTKSLQPDQYPGTIPSEVWIPGIXXXXXXXXXXXXTQKPLTTPGGNAISSHKSTLA 2647
            MIYAFLNNPKMNFNAFIHLFFILLKFSYSTSSDECTKSTPMWYSLKYPYLNLLENYKLQNTAFNCPILQTRNCCNSVILKEMSSVSEIKLKGFAEEKLENLLTMFSNDSYILMNMYLNDLENTKNDLNQLFSATYGYNYKVEKNFFFSWFDKLKMYMEGKKHNIGQLLDEFFLEMAGKIVKILIPPESSPEVTKCQIDRLIEAKPYQEADNSLKKNIIRSYAPSRMFVNAIAVGRDGFRALMNKITPSSNCVAQFNTQFHCMLCNGLTVKTCPVSCKSVMENCFGSFKLAELKKLDKIFTKYLSALFELANKLDNQLNFPAVNHKMNVQISTAIMNIQNIYPTIKEQIKAKCQNTGSKVRRKRQVAKEFVAWQTKLGDESPFW+KKLNDNLKSGVSKKTPVGSQNTKLNDFLSPMSRRIKTKYKALEGYFLRGVHDFCTLNSQSNESSSTQCWNGTLPGIVTDKNNKKKLDKSSVSVFKTVTNNLKDITMKINDLLRDKVPDPETVAVEDYLLYKSKPSSKRTGKPIKPTLAPSIEGSGDFENFPISPGEQTKKIEPEEVKPTLPPPNAGKPILEEDNNQNNKIPEQPKISHNPSWEGSGDTSENKPDTKPFNQLPVNTPEKKSSILVPRNTSTPSLVKVVIQSSTESNINTDDEDMVSRLPNIVPEKPIITSSSKPNIIPEGSGSDPDFAANKPQIPAVESITTITTTASLPDKPVEGSGSEVDPPQEVPRPVLPMIPEIQGSTIKPPSSRDSKFNPDEEKSIEGSGRAGGGGGGGGGEGGEGGAAIQRISPKPETITDYHHRQSTLSPTKSLQPDQYPGTIPSEVWIPGIVDVKNSNKDKDDTQKPLTTPGGNAISSHKSTLA
Sbjct:    1 MIYAFLNNPKMNFNAFIHLFFILLKFSYSTSSDECTKSTPMWYSLKYPYLNLLENYKLQNTAFNCPILQTRNCCNSVILKEMSSVSEIKLKGFAEEKLENLLTMFSNDSYILMNMYLNDLENTKNDLNQLFSATYGYNYKVEKNFFFSWFDKLKMYMEGKKHNIGQLLDEFFLEMAGKIVKILIPPESSPEVTKCQIDRLIEAKPYQEADNSLKKNIIRSYAPSRMFVNAIAVGRDGFRALMNKITPSSNCVAQFNTQFHCMLCNGLTVKTCPVSCKSVMENCFGSFKLAELKKLDKIFTKYLSALFELANKLDNQLNFPAVNHKMNVQISTAIMNIQNIYPTIKEQIKAKCQNTGSKVRRKRQVAKEFVAWQTKLGDESPFWEKKLNDNLKSGVSKKTPVGSQNTKLNDFLSPMSRRIKTKYKALEGYFLRGVHDFCTLNSQSNESSSTQCWNGTLPGIVTDKNNKKKLDKSSVSVFKTVTNNLKDITMKINDLLRDKVPDPETVAVEDYLLYKSKPSSKRTGKPIKPTLAPSIEGSGDFENFPISPGEQTKKIEPEEVKPTLPPPNAGKPILEEDNNQNNKIPEQPKISHNPSWEGSGDTSENKPDTKPFNQLPVNTPEKKSSILVPRNTSTPSLVKVVIQSSTESNINTDDEDMVSRLPNIVPEKPIITSSSKPNIIPEGSGSDPDFAANKPQIPAVESITTITTTASLPDKPVEGSGSEVDPPQEVPRPVLPMIPEIQGSTIKPPSSRDSKFNPDEEKSIEGSGRAGGGGGGGGGEGGEGGAAIQRISPKPETITDYHHRQSTLSPTKSLQPDQYPGTIPSEVWIPGIVDVKNSNKDKDDTQKPLTTPGGNAISSHKSTLA 865
[Close]
BLAST of Glypican-1 vs. Planmine SMEST
Match: SMESG000032627.1 (SMESG000032627.1)

HSP 1 Score: 1610.51 bits (4169), Expect = 0.000e+0
Identity = 854/855 (99.88%), Postives = 855/855 (100.00%), Query Frame = 2 
Query:   83 MNFNAFIHLFFILLKFSYSTSSDECTKSTPMWYSLKYPYLNLLENYKLQNTAFNCPILQTRNCCNSVILKEMSSVSEIKLKGFAEEKLENLLTMFSNDSYILMNMYLNDLENTKNDLNQLFSATYGYNYKVEKNFFFSWFDKLKMYMEGKKHNIGQLLDEFFLEMAGKIVKILIPPESSPEVTKCQIDRLIEAKPYQEADNSLKKNIIRSYAPSRMFVNAIAVGRDGFRALMNKITPSSNCVAQFNTQFHCMLCNGLTVKTCPVSCKSVMENCFGSFKLAELKKLDKIFTKYLSALFELANKLDNQLNFPAVNHKMNVQISTAIMNIQNIYPTIKEQIKAKCQNTGSKVRRKRQVAKEFVAWQTKLGDESPFWKKKLNDNLKSGVSKKTPVGSQNTKLNDFLSPMSRRIKTKYKALEGYFLRGVHDFCTLNSQSNESSSTQCWNGTLPGIVTXXXXXXXXXXXXXXXXXTVTNNLKDITMKINDLLRDKVPDPETVAVEDYLLYKSKPSSKRTGKPIKPTLAPSIEGSGDFENFPISPGEQTKKIEPEEVKPTLPPPNAGKPILEEDNNQNNKIPEQPKISHNPSWEGSGDTSENKPDTKPFNQLPVNTPEKKSSILVPRNTSTPSLVKVVIQSSTESNINTDDEDMVSRLPNIVPEKPIITSSSKPNIIPEGSGSDPDFAANKPQIPAVESITTITTTASLPDKPVEGSGSEVDPPQEVPRPVLPMIPEIQGSTIKPPSSRDSKFNPDEEKSIXXXXXXXXXXXXXXXXXXXXXXXIQRISPKPETITDYHHRQSTLSPTKSLQPDQYPGTIPSEVWIPGIXXXXXXXXXXXXTQKPLTTPGGNAISSHKSTLA 2647
            MNFNAFIHLFFILLKFSYSTSSDECTKSTPMWYSLKYPYLNLLENYKLQNTAFNCPILQTRNCCNSVILKEMSSVSEIKLKGFAEEKLENLLTMFSNDSYILMNMYLNDLENTKNDLNQLFSATYGYNYKVEKNFFFSWFDKLKMYMEGKKHNIGQLLDEFFLEMAGKIVKILIPPESSPEVTKCQIDRLIEAKPYQEADNSLKKNIIRSYAPSRMFVNAIAVGRDGFRALMNKITPSSNCVAQFNTQFHCMLCNGLTVKTCPVSCKSVMENCFGSFKLAELKKLDKIFTKYLSALFELANKLDNQLNFPAVNHKMNVQISTAIMNIQNIYPTIKEQIKAKCQNTGSKVRRKRQVAKEFVAWQTKLGDESPFW+KKLNDNLKSGVSKKTPVGSQNTKLNDFLSPMSRRIKTKYKALEGYFLRGVHDFCTLNSQSNESSSTQCWNGTLPGIVTDKNNKKKLDKSSVSVFKTVTNNLKDITMKINDLLRDKVPDPETVAVEDYLLYKSKPSSKRTGKPIKPTLAPSIEGSGDFENFPISPGEQTKKIEPEEVKPTLPPPNAGKPILEEDNNQNNKIPEQPKISHNPSWEGSGDTSENKPDTKPFNQLPVNTPEKKSSILVPRNTSTPSLVKVVIQSSTESNINTDDEDMVSRLPNIVPEKPIITSSSKPNIIPEGSGSDPDFAANKPQIPAVESITTITTTASLPDKPVEGSGSEVDPPQEVPRPVLPMIPEIQGSTIKPPSSRDSKFNPDEEKSIEGSGRAGGGGGGGGGEGGEGGAAIQRISPKPETITDYHHRQSTLSPTKSLQPDQYPGTIPSEVWIPGIVDVKNSNKDKDDTQKPLTTPGGNAISSHKSTLA
Sbjct:    1 MNFNAFIHLFFILLKFSYSTSSDECTKSTPMWYSLKYPYLNLLENYKLQNTAFNCPILQTRNCCNSVILKEMSSVSEIKLKGFAEEKLENLLTMFSNDSYILMNMYLNDLENTKNDLNQLFSATYGYNYKVEKNFFFSWFDKLKMYMEGKKHNIGQLLDEFFLEMAGKIVKILIPPESSPEVTKCQIDRLIEAKPYQEADNSLKKNIIRSYAPSRMFVNAIAVGRDGFRALMNKITPSSNCVAQFNTQFHCMLCNGLTVKTCPVSCKSVMENCFGSFKLAELKKLDKIFTKYLSALFELANKLDNQLNFPAVNHKMNVQISTAIMNIQNIYPTIKEQIKAKCQNTGSKVRRKRQVAKEFVAWQTKLGDESPFWEKKLNDNLKSGVSKKTPVGSQNTKLNDFLSPMSRRIKTKYKALEGYFLRGVHDFCTLNSQSNESSSTQCWNGTLPGIVTDKNNKKKLDKSSVSVFKTVTNNLKDITMKINDLLRDKVPDPETVAVEDYLLYKSKPSSKRTGKPIKPTLAPSIEGSGDFENFPISPGEQTKKIEPEEVKPTLPPPNAGKPILEEDNNQNNKIPEQPKISHNPSWEGSGDTSENKPDTKPFNQLPVNTPEKKSSILVPRNTSTPSLVKVVIQSSTESNINTDDEDMVSRLPNIVPEKPIITSSSKPNIIPEGSGSDPDFAANKPQIPAVESITTITTTASLPDKPVEGSGSEVDPPQEVPRPVLPMIPEIQGSTIKPPSSRDSKFNPDEEKSIEGSGRAGGGGGGGGGEGGEGGAAIQRISPKPETITDYHHRQSTLSPTKSLQPDQYPGTIPSEVWIPGIVDVKNSNKDKDDTQKPLTTPGGNAISSHKSTLA 855
[Close]
BLAST of Glypican-1 vs. Planmine SMEST
Match: SMESG000052359.1 (SMESG000052359.1)

HSP 1 Score: 247.669 bits (631), Expect = 3.818e-69
Identity = 186/643 (28.93%), Postives = 309/643 (48.06%), Query Frame = 2 
Query:   98 FIHLFFILLKFSYSTSSDECTKSTPMWYSLKYPYLNLLENYKLQNTA-FNCPILQTRNCCNSVILKEMSSVSEIKLKGFAEEKLENLLTMFSNDSYILMNMYLNDLENTKNDLNQLFSATYGYNYKVEKNFFFSWFDKLKMYMEGKKHNIGQLLDEFFLEMAGKIVKILIPPESSPEVTKCQIDRLIEAKPYQEADNSLKKNIIRSYAPSRMFVNAIAVGRDGFRALMNKITPSSNCVAQFNTQFHCMLCNGLTVKTCPVSCKSVMENCFGSFKLAELKKLDKIFTKYLSALFELANKLDNQLNFPAVNHKMNVQISTAIMNIQNIYPTIKEQIKAKCQNTGSKVRRKRQVAKEFVAWQTKLGDESPFWKKKLNDNLKSGVSKKTPVGSQNTKLNDFLSPMSRRIKTKYKALEGYFLRGVHDFCTLNSQSNESSSTQCWNGTLPGIVT-----XXXXXXXXXXXXXXXXXTVTNNLKDITMKINDLLRDKVPDPETVAV---------EDYLLYKSKPSSKRTG---------------KPIKPTLAP------SIEGSGDFEN-----------FPISPGEQTKKIEPEEVKPTLPPPNAGKPILEEDNNQNNKIPEQPKISHNPSWEGSG--DTSENKPDT 1879
             I + F L +   + +  +C      WYS KY Y + L  +    T    CP      CC++ +  E+  VS++KLK  AE  L++++ +  N+S  L + Y N+L+ +K+ +N++F +TY  +YK  + F F ++DKLK+YM+GK+ NI ++LD FF EMA KI+++ I  +++ E  +C  +  ++  PYQ  D ++  N   +Y  +RM VN++    D F  L  K+ PS  C  ++   F+C  C+      C   CKS++  CFGSF   E+ K++K +   L AL +++NK  +  NF  VN+ ++++IS A+MN+ N Y +I+++++A C+N   K+ RKR+ ++E          ES +++   N      +S+  P+      LND ++ +  ++K     L+ Y          L  Q N     QCWNG    I T      K      +     + KT    L+ IT  +N++L  +V DP+   +         E   L  S+ S +  G               KP  PT+ P       IEGSG+ +            FP  P       +P ++  + P P+      +++ N+N K P +P     P  EGSG  DT E   +T
Sbjct:   10 IITVLFALFENQNAQNDVDCQAIKTRWYSHKYQYSDDLLKFTTSKTVDVICP---KTTCCDNAMKTEILGVSQMKLKSIAEIHLKSIIELLYNNSRDLNDFYQNNLDISKDQMNKMFLSTYASSYKDNQRFLFDFYDKLKLYMDGKEQNIEKILDTFFTEMAEKILRMSILSKNNAEKIRCLTNSFLKLNPYQNVDKAIVSNFKEAYPTARMLVNSLRAAHDVFLDLSQKLMPSIECTTKYAKAFYCSWCSLTETMPCDGLCKSIIGKCFGSFNRKEMNKINKAWKALLGALEKISNKAKHPFNFVEVNNNLHLKISEAVMNVHNFYTSIRDKLQANCEN---KLIRKRRNSEE--------ESESQYFE---NVPKTLEISQPKPI-----LLNDLVNKLLTKMKDMTLHLQNYKNTICSSTFKLPKQGN-----QCWNGA--EITTGYKPNVKEKDANKNLKISPLVKTSIATLQKITAALNNILSKQVVDPDAFKIKFVEKPKITEIPRLRPSRISEQMEGSGKGGVDIENTSNKSKPKLPTIEPIKEPKEIIEGSGEIKTPSNEISKNRPAFPQLPPNNINTPKPGKITKSPPIPDDEDLPTDQNENKNEKTP-KPAEPRTPQIEGSGSLDTVEKSTET 622
The following BLAST results are available for this feature:
BLAST of Glypican-1 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
GPC65.977e-2823.54glypican 6 [Source:HGNC Symbol;Acc:HGNC:4454][more]
GPC42.033e-2224.83glypican 4 [Source:HGNC Symbol;Acc:HGNC:4452][more]
GPC22.682e-1920.73glypican 2 [Source:HGNC Symbol;Acc:HGNC:4450][more]
GPC11.464e-1420.78glypican 1 [Source:HGNC Symbol;Acc:HGNC:4449][more]
GPC11.339e-1222.66glypican 1 [Source:HGNC Symbol;Acc:HGNC:4449][more]
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BLAST of Glypican-1 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Glypican-1 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 2
Match NameE-valueIdentityDescription
dlp1.032e-1922.06gene:FBgn0041604 transcript:FBtr0333032[more]
dlp1.043e-1922.06gene:FBgn0041604 transcript:FBtr0075679[more]
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BLAST of Glypican-1 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
gpc6b1.725e-2925.19glypican 6b [Source:ZFIN;Acc:ZDB-GENE-130515-2][more]
gpc6a3.308e-2524.59glypican 6a [Source:ZFIN;Acc:ZDB-GENE-071004-15][more]
gpc41.764e-2426.20glypican 4 [Source:ZFIN;Acc:ZDB-GENE-011119-1][more]
gpc1a4.858e-2022.15glypican 1a [Source:NCBI gene;Acc:553367][more]
gpc1a6.568e-2022.15glypican 1a [Source:NCBI gene;Acc:553367][more]
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BLAST of Glypican-1 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
GPC49.370e-2824.05glypican 4 [Source:NCBI gene;Acc:100126682][more]
GPC61.970e-2326.09glypican 6 [Source:NCBI gene;Acc:100491173][more]
atf26.638e-1721.67activating transcription factor 2 [Source:Xenbase;... [more]
atf27.892e-1721.67activating transcription factor 2 [Source:Xenbase;... [more]
atf21.054e-1621.67activating transcription factor 2 [Source:Xenbase;... [more]
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BLAST of Glypican-1 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Gpc65.669e-2823.54glypican 6 [Source:MGI Symbol;Acc:MGI:1346322][more]
Gpc65.669e-2823.54glypican 6 [Source:MGI Symbol;Acc:MGI:1346322][more]
Gpc68.105e-2727.17glypican 6 [Source:MGI Symbol;Acc:MGI:1346322][more]
Gpc48.773e-2425.17glypican 4 [Source:MGI Symbol;Acc:MGI:104902][more]
Gpc18.297e-1620.39glypican 1 [Source:MGI Symbol;Acc:MGI:1194891][more]
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BLAST of Glypican-1 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q9Y625|GPC6_HUMAN2.870e-2723.54Glypican-6 OS=Homo sapiens OX=9606 GN=GPC6 PE=1 SV... [more]
sp|Q9R087|GPC6_MOUSE3.966e-2723.54Glypican-6 OS=Mus musculus OX=10090 GN=Gpc6 PE=1 S... [more]
sp|Q5RE54|GPC6_PONAB4.261e-2723.54Glypican-6 OS=Pongo abelii OX=9601 GN=GPC6 PE=2 SV... [more]
sp|P51655|GPC4_MOUSE6.136e-2325.17Glypican-4 OS=Mus musculus OX=10090 GN=Gpc4 PE=1 S... [more]
sp|O75487|GPC4_HUMAN9.764e-2224.83Glypican-4 OS=Homo sapiens OX=9606 GN=GPC4 PE=1 SV... [more]
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BLAST of Glypican-1 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
I1ZI581.600e-6528.95Glypican-1 OS=Schmidtea mediterranea OX=79327 PE=2... [more]
A0A4Z2DX732.140e-4025.14Glypican-4 OS=Schistosoma japonicum OX=6182 GN=EWB... [more]
C1LFG92.566e-4025.33Glypican-4 OS=Schistosoma japonicum OX=6182 GN=Xgl... [more]
A0A183MKF26.716e-3828.13Uncharacterized protein OS=Schistosoma margrebowie... [more]
A0A094ZZE71.709e-3727.47Glypican-6 OS=Schistosoma haematobium OX=6185 GN=M... [more]
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BLAST of Glypican-1 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
gpc6b3.174e-2725.44glypican 6b [Source:ZFIN;Acc:ZDB-GENE-130515-2][more]
gpc6b1.415e-2625.25glypican 6b [Source:ZFIN;Acc:ZDB-GENE-130515-2][more]
gpc6a8.460e-2626.57glypican 6a [Source:ZFIN;Acc:ZDB-GENE-071004-15][more]
gpc43.952e-2224.85glypican-4 [Source:NCBI gene;Acc:103025650][more]
gpc1a2.635e-1921.70glypican 1a [Source:NCBI gene;Acc:553367][more]
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BLAST of Glypican-1 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Glypican-1 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Glypican-1 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Glypican-1 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
gpc25.971e-2521.36glypican 2 [Source:NCBI gene;Acc:101173153][more]
gpc25.971e-2521.36glypican 2 [Source:NCBI gene;Acc:101173153][more]
gpc6a4.569e-2422.61glypican-6 [Source:NCBI gene;Acc:101172317][more]
gpc6a1.253e-2325.43glypican-6 [Source:NCBI gene;Acc:101172317][more]
gpc41.645e-2124.66glypican-6 [Source:NCBI gene;Acc:101160491][more]
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BLAST of Glypican-1 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 3
Match NameE-valueIdentityDescription
SMESG000032627.10.000e+099.88SMESG000032627.1[more]
SMESG000032627.10.000e+099.88SMESG000032627.1[more]
SMESG000052359.13.818e-6928.93SMESG000052359.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30027983 ID=SMED30027983|Name=Glypican-1|organism=Schmidtea mediterranea sexual|type=transcript|length=3385bp
ATATTAAATAGATTTAAAATCATATTAATCCACAAATTTATCAAAATTGT
CAATGATTTATGCTTTCCTTAATAATCCTAAAATGAATTTTAATGCATTT
ATTCATTTATTTTTTATTCTTCTAAAATTTTCATATTCCACTTCATCAGA
TGAATGTACGAAATCGACTCCAATGTGGTATTCATTGAAATACCCATATT
TAAATCTGCTGGAGAATTATAAATTACAAAACACTGCTTTCAATTGCCCA
ATTTTACAAACGAGAAATTGCTGTAATTCTGTTATTTTAAAGGAAATGTC
AAGTGTGAGTGAAATTAAATTAAAAGGATTTGCTGAAGAAAAATTAGAAA
ACCTCTTGACGATGTTTAGCAATGACAGTTACATTCTAATGAATATGTAT
TTAAATGATCTGGAAAACACGAAAAACGATCTCAATCAACTATTTAGTGC
TACTTACGGATACAATTATAAAGTGGAAAAGAATTTCTTTTTCAGCTGGT
TTGATAAATTGAAAATGTATATGGAAGGCAAGAAACACAACATTGGACAG
TTGTTGGATGAGTTTTTCCTTGAGATGGCTGGGAAAATCGTTAAGATTTT
AATCCCTCCTGAATCGAGTCCAGAAGTCACCAAATGCCAAATAGATCGGC
TAATTGAAGCTAAACCTTACCAGGAAGCCGACAACAGTTTAAAGAAAAAC
ATAATTCGCTCATACGCTCCATCAAGAATGTTTGTCAATGCAATTGCAGT
TGGACGGGATGGTTTTAGAGCTCTAATGAACAAGATAACTCCTAGTTCCA
ACTGTGTAGCACAATTTAATACTCAGTTTCATTGTATGCTATGTAACGGA
TTGACAGTCAAAACCTGTCCTGTGTCATGTAAAAGTGTAATGGAGAATTG
TTTTGGTTCATTTAAGTTGGCTGAGTTGAAAAAACTCGACAAGATTTTCA
CTAAATATTTAAGTGCTCTATTTGAACTTGCCAATAAATTAGATAATCAG
TTAAATTTCCCGGCAGTTAATCATAAGATGAATGTGCAAATATCGACTGC
CATAATGAACATACAAAATATTTATCCAACAATTAAAGAGCAAATCAAAG
CTAAATGTCAAAACACTGGAAGCAAAGTTCGAAGAAAAAGACAGGTTGCG
AAAGAATTTGTAGCTTGGCAAACCAAATTAGGCGACGAGTCCCCGTTTTG
GAAAAAAAAATTAAATGATAATTTAAAGTCCGGTGTATCCAAGAAAACTC
CGGTGGGCTCTCAAAATACTAAACTCAATGATTTTCTCTCTCCAATGTCC
AGAAGGATTAAAACAAAGTATAAGGCATTGGAAGGCTATTTCCTTAGAGG
TGTTCATGATTTTTGTACACTGAATTCACAATCTAATGAGTCGTCGTCTA
CTCAGTGTTGGAATGGAACGTTACCTGGTATTGTTACGGATAAAAATAAC
AAAAAAAAACTCGATAAGTCTTCCGTTTCAGTATTTAAAACTGTGACAAA
TAATTTGAAAGATATTACAATGAAAATAAACGATTTATTGAGGGACAAAG
TCCCAGATCCTGAAACTGTTGCCGTTGAAGATTATTTACTATATAAATCT
AAGCCTTCTAGTAAACGAACTGGAAAACCGATAAAACCTACTCTTGCCCC
CTCAATTGAAGGCAGTGGTGATTTTGAAAATTTCCCCATTAGTCCAGGCG
AACAAACAAAAAAGATTGAACCAGAAGAAGTCAAACCAACTCTTCCACCC
CCAAATGCTGGGAAACCCATTTTAGAAGAAGATAATAATCAAAATAATAA
AATTCCTGAACAACCTAAAATTTCACATAATCCCTCGTGGGAAGGTAGTG
GGGATACATCAGAAAATAAACCTGACACTAAACCTTTCAACCAATTACCT
GTAAATACACCAGAAAAAAAGTCATCGATTTTAGTTCCTAGAAATACTTC
TACTCCTTCCCTTGTGAAAGTTGTGATCCAATCGTCAACTGAATCAAATA
TAAATACAGATGATGAAGATATGGTTTCAAGATTACCAAATATTGTACCT
GAAAAGCCTATAATTACCTCATCTTCAAAACCGAATATTATACCAGAGGG
TAGCGGCTCAGATCCCGATTTCGCTGCAAATAAACCACAAATACCGGCTG
TTGAATCTATAACTACGATTACGACAACAGCTAGCTTGCCAGATAAACCA
GTCGAAGGTTCAGGATCAGAAGTCGATCCACCACAAGAAGTTCCCCGTCC
TGTTCTTCCAATGATACCAGAAATTCAAGGAAGTACAATTAAACCGCCTT
CATCGAGAGACTCCAAGTTCAATCCGGACGAAGAGAAATCGATTGAAGGT
AGCGGTAGAGCAGGAGGAGGAGGGGGAGGAGGGGGAGGAGAAGGAGGAGA
AGGAGGAGCTGCAATTCAGCGGATATCTCCCAAACCAGAAACTATTACTG
ATTATCATCATCGTCAGTCAACATTAAGCCCGACAAAATCTCTCCAACCC
GATCAATATCCCGGCACAATTCCATCAGAGGTTTGGATTCCCGGCATTGT
CGATGTGAAAAACTCTAACAAAGACAAAGACGACACTCAGAAACCGCTGA
CGACTCCAGGTGGCAATGCAATTTCCAGTCACAAATCAACCCTTGCTACA
ATTACCGTCACAACGCTCAGTCTTTTATTTGTATTATTATTAAACTGCCT
AAAATAAATCCCATCAAACTAACTGATAATAATTGTATTATTTGCAATAT
TTTATTGTCATACTTTCCATTGACCAATATAATATATATATATATATGTA
TATAATTTTTAGAATATTCTCGTGATAAAGCTGAAATACTATACACCGAT
ACCTCACTTTGCATTGCTTCCGTTTGCGTTGCAAATTTTATGATACTCAA
TTTTCAGTTTGCGTTTAAATTGTTTCACATTTTGTTGCGTTTTTATTTGT
AATTTTGCATTCAATAGTCAAAAAATAGATTGTAGAAATTTAAATAAAAA
TATCCACGTGAAATAGAGAAACAGTATTTTTTCTATTCATTTTCTTACAT
TGCGTCGATAGTCAAGTCGTATTTTTATTTTATGCAATTTTTGTTCACAT
TTTTAGATTGACCTGAATTTTACCGAGATATCAAAAATCATCAGAAAAAT
TCTATATATTTAGTCTGATATAAAAGATTTGGAGAACATAGCTAACACCA
TCCAATGTACTTTGAAGAAAATTTTAGTTTCAGGAGAAGAACAACAAAAA
ATAATGAATTAGAATAAAATTCAGAATGAATTTTTTTTGTCTATAATTGT
TGTTTAAACAGAATTGCGAATTCCTTGTTTTAAATTATAAACTAATACCA
TAATATAATTAATAAAATATAAAACATATCTATCA
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protein sequence of SMED30027983-orf-1

>SMED30027983-orf-1 ID=SMED30027983-orf-1|Name=SMED30027983-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=885bp
MIYAFLNNPKMNFNAFIHLFFILLKFSYSTSSDECTKSTPMWYSLKYPYL
NLLENYKLQNTAFNCPILQTRNCCNSVILKEMSSVSEIKLKGFAEEKLEN
LLTMFSNDSYILMNMYLNDLENTKNDLNQLFSATYGYNYKVEKNFFFSWF
DKLKMYMEGKKHNIGQLLDEFFLEMAGKIVKILIPPESSPEVTKCQIDRL
IEAKPYQEADNSLKKNIIRSYAPSRMFVNAIAVGRDGFRALMNKITPSSN
CVAQFNTQFHCMLCNGLTVKTCPVSCKSVMENCFGSFKLAELKKLDKIFT
KYLSALFELANKLDNQLNFPAVNHKMNVQISTAIMNIQNIYPTIKEQIKA
KCQNTGSKVRRKRQVAKEFVAWQTKLGDESPFWKKKLNDNLKSGVSKKTP
VGSQNTKLNDFLSPMSRRIKTKYKALEGYFLRGVHDFCTLNSQSNESSST
QCWNGTLPGIVTDKNNKKKLDKSSVSVFKTVTNNLKDITMKINDLLRDKV
PDPETVAVEDYLLYKSKPSSKRTGKPIKPTLAPSIEGSGDFENFPISPGE
QTKKIEPEEVKPTLPPPNAGKPILEEDNNQNNKIPEQPKISHNPSWEGSG
DTSENKPDTKPFNQLPVNTPEKKSSILVPRNTSTPSLVKVVIQSSTESNI
NTDDEDMVSRLPNIVPEKPIITSSSKPNIIPEGSGSDPDFAANKPQIPAV
ESITTITTTASLPDKPVEGSGSEVDPPQEVPRPVLPMIPEIQGSTIKPPS
SRDSKFNPDEEKSIEGSGRAGGGGGGGGGEGGEGGAAIQRISPKPETITD
YHHRQSTLSPTKSLQPDQYPGTIPSEVWIPGIVDVKNSNKDKDDTQKPLT
TPGGNAISSHKSTLATITVTTLSLLFVLLLNCLK*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: biological process
TermDefinition
GO:0009966regulation of signal transduction
Vocabulary: cellular component
TermDefinition
GO:0046658anchored component of plasma membrane
GO:0016020membrane
GO:0005578proteinaceous extracellular matrix
Vocabulary: INTERPRO
TermDefinition
IPR023795Serpin_CS
IPR001863Glypican
Vocabulary: molecular function
TermDefinition
GO:0043395heparan sulfate proteoglycan binding
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR001863GlypicanPFAMPF01153Glypicancoord: 65..456
e-value: 3.7E-38
score: 131.7
IPR001863GlypicanPANTHERPTHR10822GLYPICANcoord: 30..829
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 802..820
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 705..823
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 651..678
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 518..630
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 574..630
NoneNo IPR availableSIGNALP_EUKSignalP-noTMSignalP-noTMcoord: 1..32
score: 0.669
NoneNo IPR availableTMHMMTMhelixcoord: 864..883