Calpain-5

Query:  159 MFDKPILYKNQNYTKIKSQLLETNTMFTDKEFPPNLTSLFSTLSNYDLTQNEELNNIRWRRPGQICENPYLFVNGVSTNDVLQGRLGNCWFVAACTCITVYRENWMMLIPDYKSQEWTKEDKSEYCGIFKFRFWKYGQWTEVVIDDQLPTLENDLIYCHSNYRNEFWSALLEKAYAKILGSYEALEGGELIESLVDFTGGLAEPIVITDDHLKPD--KSSKLFQYLLKEHGNKSLIAAAIPAMTPEEQEEETSMGLIIGHAYAITMVIDLPVDTSKSDLKLVQSKVSNGHIRMMRLRNPWGQGEWKGPFCDGSPEWDVVSKSSRHRVGLTFQDDGEFWMTFIDFLNNFKSVVICHQINS---IFNKVYYESVFHSEWS------KGFSGGCLNFKNTFLDNPQYAFDINSADGEEVQFCLTQKMIRELNRNGGATGLLHIGYSILKVEANRQYRVHRLDHCLLEQSSAFKNGRSIFLRLHLKRGRYIAVPCTFQPGQIQSFMFRIYSKNSINTGELTQSLPSPGMSNYLVKVPEVATRISIFKAISLPRLDPIHGANPFFVLICENQKCISSICHGTMEPEWDESFIFYRKYFSKEPIVLLVYSRSGIIDEFIGK 1970
            MF     Y++QNY+ ++        +F D  FP    SL+     Y  T       +RW+RP  ICE+P LFV+G+S++D+ QG++GNCWFVAAC+ +      W  +IPD+K QEW  E  + Y GIF F FW++G+W +VVIDD+LPT+ N LIYCHSN RNEFW AL+EKAYAK+ G Y+AL+GG   ++LVDFTGG++EPI +T+     D  K ++LF+ +LK H    LI+A+I A+T  + E   + GL+ GHAYA+T V    V      L   +S+     + M+RLRNPWG+ EW GP+ D S EW  VSKS R ++G+T QDDGEFWMTF D    F  ++ C  IN+     +K + E+  H  W+      +   GGC+N K+TF  NPQY F++   + +EV  C+ Q+  R   R G    L  IG+ I KVE NRQYR+H L H     SS + N RS+FLR     GRY+ +P TF+PG    F+ R+++    N  EL    P     + L   P++ T++ +  A  L   D   GAN + ++ CE  K  S++  GT  PE++   IFYRK  S +PI + V++   + DEF+G+
Sbjct:    1 MFSCVKPYEDQNYSALRRDCRRRKVLFEDPLFPATDDSLY-----YKGTPGPA---VRWKRPKGICEDPRLFVDGISSHDLHQGQVGNCWFVAACSSLASRESLWQKVIPDWKEQEWDPEKPNAYAGIFHFHFWRFGEWVDVVIDDRLPTVNNQLIYCHSNSRNEFWCALVEKAYAKLAGCYQALDGGNTADALVDFTGGVSEPIDLTEGDFANDETKRNQLFERMLKVHSRGGLISASIKAVTAADMEARLACGLVKGHAYAVTDV--RKVRLGHGLLAFFKSE----KLDMIRLRNPWGEREWNGPWSDTSEEWQKVSKSEREKMGVTVQDDGEFWMTFEDVCRYFTDIIKCRVINTSHLSIHKTWEEARLHGAWTLHEDPRQNRGGGCINHKDTFFQNPQYIFEVKKPE-DEVLICIQQRPKRSTRREGKGENLA-IGFDIYKVEENRQYRMHSLQH--KAASSIYINSRSVFLRTDQPEGRYVIIPTTFEPGHTGEFLLRVFTDVPSNCRELRLDEPPHTCWSSLCGYPQLVTQVHVLGAAGLK--DSPTGANSYVIIKCEGDKVRSAVQKGTSTPEYNVKGIFYRKKLS-QPITVQVWNHRVLKDEFLGQ 594          

Query:  159 MFDKPILYKNQNYTKIKSQLLETNTMFTDKEFPPNLTSLFSTLSNYDLTQNEELNNIRWRRPGQICENPYLFVNGVSTNDVLQGRLGNCWFVAACTCITVYRENWMMLIPDYKSQEWTKEDKSEYCGIFKFRFWKYGQWTEVVIDDQLPTLENDLIYCHSNYRNEFWSALLEKAYAKILGSYEALEGGELIESLVDFTGGLAEPIVITDDHLKPD--KSSKLFQYLLKEHGNKSLIAAAIPAMTPEEQEEETSMGLIIGHAYAITMVIDLPVDTSKSDLKLVQSKVSNGHIRMMRLRNPWGQGEWKGPFCDGSPEWDVVSKSSRHRVGLTFQDDGEFWMTFIDFLNNFKSVVICHQINS---IFNKVYYESVFHSEWS------KGFSGGCLNFKNTFLDNPQYAFDINSADGEEVQFCLTQKMIRELNRNGGATGLLHIGYSILKVEANRQYRVHRLDHCLLEQSSAFKNGRSIFLRLHLKRGRYIAVPCTFQPGQIQSFMFRIYSKNSINTGELTQSLPSPGMSNYLVKVPEVATRISIFKAISLPRLDPIHGANPFFVLICENQKCISSICHGTMEPEWDESFIFYRKYFSKEPIVLLVYSRSGIIDEFIGK 1970
            MF     Y++QNY+ ++        +F D  FP    SL+     Y  T       +RW+RP  ICE+P LFV+G+S++D+ QG++GNCWFVAAC+ +      W  +IPD+K QEW  E  + Y GIF F FW++G+W +VVIDD+LPT+ N LIYCHSN RNEFW AL+EKAYAK+ G Y+AL+GG   ++LVDFTGG++EPI +T+     D  K ++LF+ +LK H    LI+A+I A+T  + E   + GL+ GHAYA+T V    V      L   +S+     + M+RLRNPWG+ EW GP+ D S EW  VSKS R ++G+T QDDGEFWMTF D    F  ++ C  IN+     +K + E+  H  W+      +   GGC+N K+TF  NPQY F++   + +EV  C+ Q+  R   R G    L  IG+ I KVE NRQYR+H L H     SS + N RS+FLR     GRY+ +P TF+PG    F+ R+++    N  EL    P     + L   P++ T++ +  A  L   D   GAN + ++ CE  K  S++  GT  PE++   IFYRK  S +PI + V++   + DEF+G+
Sbjct:    1 MFSCVKPYEDQNYSALRRDCRRRKVLFEDPLFPATDDSLY-----YKGTPGPA---VRWKRPKGICEDPRLFVDGISSHDLHQGQVGNCWFVAACSSLASRESLWQKVIPDWKEQEWDPEKPNAYAGIFHFHFWRFGEWVDVVIDDRLPTVNNQLIYCHSNSRNEFWCALVEKAYAKLAGCYQALDGGNTADALVDFTGGVSEPIDLTEGDFANDETKRNQLFERMLKVHSRGGLISASIKAVTAADMEARLACGLVKGHAYAVTDV--RKVRLGHGLLAFFKSE----KLDMIRLRNPWGEREWNGPWSDTSEEWQKVSKSEREKMGVTVQDDGEFWMTFEDVCRYFTDIIKCRVINTSHLSIHKTWEEARLHGAWTLHEDPRQNRGGGCINHKDTFFQNPQYIFEVKKPE-DEVLICIQQRPKRSTRREGKGENLA-IGFDIYKVEENRQYRMHSLQH--KAASSIYINSRSVFLRTDQPEGRYVIIPTTFEPGHTGEFLLRVFTDVPSNCRELRLDEPPHTCWSSLCGYPQLVTQVHVLGAAGLK--DSPTGANSYVIIKCEGDKVRSAVQKGTSTPEYNVKGIFYRKKLS-QPITVQVWNHRVLKDEFLGQ 594          

Query:  159 MFDKPILYKNQNYTKIKSQLLETNTMFTDKEFPPNLTSLFSTLSNYDLTQNEELNNIRWRRPGQICENPYLFVNGVSTNDVLQGRLGNCWFVAACTCITVYRENWMMLIPDYKSQEWTKEDKSEYCGIFKFRFWKYGQWTEVVIDDQLPTLENDLIYCHSNYRNEFWSALLEKAYAKILGSYEALEGGELIESLVDFTGGLAEPIVITDDHLKPD--KSSKLFQYLLKEHGNKSLIAAAIPAMTPEEQEEETSMGLIIGHAYAITMVIDLPVDTSKSDLKLVQSKVSNGHIRMMRLRNPWGQGEWKGPFCDGSPEWDVVSKSSRHRVGLTFQDDGEFWMTFIDFLNNFKSVVICHQINS---IFNKVYYESVFHSEWS------KGFSGGCLNFKNTFLDNPQYAFDINSADGEEVQFCLTQKMIRELNRNGGATGLLHIGYSILKVEANRQYRVHRLDHCLLEQSSAFKNGRSIFLRLHLKRGRYIAVPCTFQPGQIQSFMFRIYSKNSINTGELTQSLPSPGMSNYLVKVPEVATRISIFKAISLPRLDPIHGANPFFVLICENQKCISSICHGTMEPEWDESFIFYRKYFSKEPIVLLVYSRSGIIDEFIGK 1970
            MF     Y++QNY+ ++        +F D  FP    SL+     Y  T       +RW+RP  ICE+P LFV+G+S++D+ QG++GNCWFVAAC+ +      W  +IPD+K QEW  E  + Y GIF F FW++G+W +VVIDD+LPT+ N LIYCHSN RNEFW AL+EKAYAK+ G Y+AL+GG   ++LVDFTGG++EPI +T+     D  K ++LF+ +LK H    LI+A+I A+T  + E   + GL+ GHAYA+T V    V      L   +S+     + M+RLRNPWG+ EW GP+ D S EW  VSKS R ++G+T QDDGEFWMTF D    F  ++ C  IN+     +K + E+  H  W+      +   GGC+N K+TF  NPQY F++   + +EV  C+ Q+  R   R G    L  IG+ I KVE NRQYR+H L H     SS + N RS+FLR     GRY+ +P TF+PG    F+ R+++    N  EL    P     + L   P++ T++ +  A  L   D   GAN + ++ CE  K  S++  GT  PE++   IFYRK  S +PI + V++   + DEF+G+
Sbjct:    1 MFSCVKPYEDQNYSALRRDCRRRKVLFEDPLFPATDDSLY-----YKGTPGPA---VRWKRPKGICEDPRLFVDGISSHDLHQGQVGNCWFVAACSSLASRESLWQKVIPDWKEQEWDPEKPNAYAGIFHFHFWRFGEWVDVVIDDRLPTVNNQLIYCHSNSRNEFWCALVEKAYAKLAGCYQALDGGNTADALVDFTGGVSEPIDLTEGDFANDETKRNQLFERMLKVHSRGGLISASIKAVTAADMEARLACGLVKGHAYAVTDV--RKVRLGHGLLAFFKSE----KLDMIRLRNPWGEREWNGPWSDTSEEWQKVSKSEREKMGVTVQDDGEFWMTFEDVCRYFTDIIKCRVINTSHLSIHKTWEEARLHGAWTLHEDPRQNRGGGCINHKDTFFQNPQYIFEVKKPE-DEVLICIQQRPKRSTRREGKGENLA-IGFDIYKVEENRQYRMHSLQH--KAASSIYINSRSVFLRTDQPEGRYVIIPTTFEPGHTGEFLLRVFTDVPSNCRELRLDEPPHTCWSSLCGYPQLVTQVHVLGAAGLK--DSPTGANSYVIIKCEGDKVRSAVQKGTSTPEYNVKGIFYRKKLS-QPITVQVWNHRVLKDEFLGQ 594          

Query:  159 MFDKPILYKNQNYTKIKSQLLETNTMFTDKEFPPNLTSLFSTLSNYDLTQNEELNNIRWRRPG----------------------------------------QICENPYLFVNGVSTNDVLQGRLGNCWFVAACTCITVYRENWMMLIPDYKSQEWTKEDKSEYCGIFKFRFWKYGQWTEVVIDDQLPTLENDLIYCHSNYRNEFWSALLEKAYAKILGSYEALEGGELIESLVDFTGGLAEPIVITDDHLKPD--KSSKLFQYLLKEHGNKSLIAAAIPAMTPEEQEEETSMGLIIGHAYAITMVIDLPVDTSKSDLKLVQSKVSNGHIRMMRLRNPWGQGEWKGPFCDGSPEWDVVSKSSRHRVGLTFQDDGEFWMTFIDFLNNFKSVVICHQINS---IFNKVYYESVFHSEWS------KGFSGGCLNFKNTFLDNPQYAFDINSADGEEVQFCLTQKMIRELNRNGGATGLLHIGYSILKVEANRQYRVHRLDHCLLEQSSAFKNGRSIFLRLHLKRGRYIAVPCTFQPGQIQSFMFRIYSKNSINTGELTQSLPSPGMSNYLVKVPEVATRISIFKAISLPRLDPIHGANPFFVLICENQKCISSICHGTMEPEWDESFIFYRKYFSKEPIVLLVYSRSGIIDEFIGK 1970
            MF     Y++QNY+ ++        +F D  FP    SL+     Y  T       +RW+RP                                          ICE+P LFV+G+S++D+ QG++GNCWFVAAC+ +      W  +IPD+K QEW  E  + Y GIF F FW++G+W +VVIDD+LPT+ N LIYCHSN RNEFW AL+EKAYAK+ G Y+AL+GG   ++LVDFTGG++EPI +T+     D  K ++LF+ +LK H    LI+A+I A+T  + E   + GL+ GHAYA+T V    V      L   +S+     + M+RLRNPWG+ EW GP+ D S EW  VSKS R ++G+T QDDGEFWMTF D    F  ++ C  IN+     +K + E+  H  W+      +   GGC+N K+TF  NPQY F++   + +EV  C+ Q+  R   R G    L  IG+ I KVE NRQYR+H L H     SS + N RS+FLR     GRY+ +P TF+PG    F+ R+++    N  EL    P     + L   P++ T++ +  A  L   D   GAN + ++ CE  K  S++  GT  PE++   IFYRK  S +PI + V++   + DEF+G+
Sbjct:    1 MFSCVKPYEDQNYSALRRDCRRRKVLFEDPLFPATDDSLY-----YKGTPGPA---VRWKRPKYSGHSLAPHRPGWGDARRMENVPRPGSSGCPSSSLRARDLGICEDPRLFVDGISSHDLHQGQVGNCWFVAACSSLASRESLWQKVIPDWKEQEWDPEKPNAYAGIFHFHFWRFGEWVDVVIDDRLPTVNNQLIYCHSNSRNEFWCALVEKAYAKLAGCYQALDGGNTADALVDFTGGVSEPIDLTEGDFANDETKRNQLFERMLKVHSRGGLISASIKAVTAADMEARLACGLVKGHAYAVTDV--RKVRLGHGLLAFFKSE----KLDMIRLRNPWGEREWNGPWSDTSEEWQKVSKSEREKMGVTVQDDGEFWMTFEDVCRYFTDIIKCRVINTSHLSIHKTWEEARLHGAWTLHEDPRQNRGGGCINHKDTFFQNPQYIFEVKKPE-DEVLICIQQRPKRSTRREGKGENLA-IGFDIYKVEENRQYRMHSLQH--KAASSIYINSRSVFLRTDQPEGRYVIIPTTFEPGHTGEFLLRVFTDVPSNCRELRLDEPPHTCWSSLCGYPQLVTQVHVLGAAGLK--DSPTGANSYVIIKCEGDKVRSAVQKGTSTPEYNVKGIFYRKKLS-QPITVQVWNHRVLKDEFLGQ 634          

Query:  177 LYKNQNYTKIKSQLLETNTMFTDKEFPPNLTSLFSTLSNYDLTQNEEL-NNIRWRRPGQICENPYLFVNGVSTNDVLQGRLGNCWFVAACTCITVYRENWMMLIPDYKSQEWTKEDKSEYCGIFKFRFWKYGQWTEVVIDDQLPTLENDLIYCHSNYRNEFWSALLEKAYAKILGSYEALEGGELIESLVDFTGGLAEPIVITDDHLKP--DKSSKLFQYLLKEHGNKSLIAAAIPAMTPEEQEEETSMGLIIGHAYAITMVIDLPVDTSKSDLKLVQSKVSNGHIRMMRLRNPWGQGEWKGPFCDGSPEWDVVSKSSRHRVGLTFQDDGEFWMTFIDFLNNFKSVVICHQINS-IFNKVYYESVFHSEWS------KGFSGGCLNFKNTFLDNPQYAFDINSADGEEVQFCLTQKMIRELNRNGGATGLLHIGYSILKVEANRQYRVHRLDHCLLEQSSAFKNGRSIFLRLHLKRGRYIAVPCTFQPGQIQSFMFRIYSKNSINTGELTQSLPSPGMSNYLVKVPEVATRISIFKAISLPRLDPIHGANPFFVLICENQKCISSICHGTMEPEWDESFIFYRKYFSKEPIVLLVYSRSGIIDEFIGKQAFEGN 1988
            L+KNQ Y ++K + ++ + +F D  F P   SLF          N  L   + W+RP  IC++P+L V  +S + + QGRLG+   V+A +C+ V   +W   IP++K QEW  +   +Y GIF FRFW +G+WTEVVIDD LPT+  DL++  S   NEFW+ALLEKAYAK+LG YEAL+G  + + +VDFTG LAE + +         ++  KLF  L K      LI  +I +   EEQE ET  GL+ GH Y +T +  + +       +LV+   S   + M+RLRNP G+ EW GP+ + S EW  ++ S R  +GL   DDGEFWM+  DF  NF  + +C  +N+ IF +   ESV    W+         SGGC N ++TFL NPQY F +   DG +V   L QK +R   R G     + IG+ + KVE NR++R+H L       +S + + R++FL  +LK+G Y+ VP  FQ G+   F+ RI+S+  +   ELT  +P     N     P+V T+I++  A  L +       NP+ V+ C  ++  S +   T+   +D   IFYR+  +  PI++ V++     D+F+G+   + +
Sbjct:    7 LFKNQKYQELKQECIKDSRLFCDPTFLPENDSLFY---------NRLLPGKVVWKRPQDICDDPHLIVGNISNHQLTQGRLGHKPMVSAFSCLAVQESHWTKTIPNHKEQEWDPQKTEKYAGIFHFRFWHFGEWTEVVIDDLLPTINGDLVFSFSTSMNEFWNALLEKAYAKLLGCYEALDGLTITDIIVDFTGTLAETVDMQKGRYTELVEEKYKLFGELYKTFTKGGLICCSIESPNQEEQEVETDWGLLKGHTYTMTDIRKIRLGE-----RLVEV-FSAEKVYMVRLRNPLGRQEWSGPWSEISEEWQQLTASDRKNLGLVMSDDGEFWMSLEDFCRNFHKLNVCRNVNNPIFGRKELESVLGC-WTVDDDPLMNRSGGCYNNRDTFLQNPQYIFTV-PEDGHKVIMSLQQKDLRTYRRMGRPDNYI-IGFELFKVEMNRKFRLHHLYIQERAGTSTYIDTRTVFLSKYLKKGNYVLVPTMFQHGRTSEFLLRIFSEVPVQLRELTLDMPKMSCWNLARGYPKVVTQITVHSAEDLEKKYANETVNPYLVIKCGKEEVRSPVQKNTVHAIFDTQAIFYRRT-TDIPIIVQVWNSRKFCDQFLGQVTLDAD 601          

Query:  180 YKNQNYTKIKSQLLETNTMFTDKEFPPNLTSLFSTLSNYDLTQNEELNNIRWRRPGQICENPYLFVNGVSTNDVLQGRLGNCWFVAACTCITVYRENWMMLIPDYKSQEWTKEDKSEYCGIFKFRFWKYGQWTEVVIDDQLPTLENDLIYCHSNYRNEFWSALLEKAYAKILGSYEALEGGELIESLVDFTGGLAEPIVITDDHLKPDKSS---KLFQYLLKEHGNKSLIAAAIPAMTPEEQEEETSMGLIIGHAYAITMV--IDLPVDTSKSDLKLVQSKVSNGHIRMMRLRNPWGQGEWKGPFCDGSPEWDVVSKSSRHRVGL----TFQDDGEFWMTFIDFLNNFKSVVICHQINS---IFNKVYYESVFHSEWSKG---------FSGGCLNFKNTFLDNPQYAFDINSADGEEVQFCLTQKMIRELNRNGGATGL------LHIGYSILKVEANRQYRVHRLDHCLLEQSSAFKNGRSIFLRLH-LKRGRYIAVPCTFQPGQIQSFMFRIYSKNSINTGELTQSLPSPGMSNYLVKVPEVATRISI----FKAISLPRLDPIHGANPFFVLICENQKCI-SSICHGTMEPEWDESFIFYR 1895
            + NQNY K++   ++    F D  FPP   SLF         +  + ++I W+RPG++  +P+LFV G S NDV QG LGNCWFV+AC+ +T   +    +IPD   QEW+   K  Y GIF+FRFW++G+W EVVIDD LPT +  L++  S   NEFWSALLEKA+AK+ G YE L GG L ++L D +GG+AE + +    LK D +    KLF  L       +L+ AAI A T EE EE    GL+ GHAYA++ V  ID+     +S    +    S     ++RL+NPWG+ EW G + D SPEW  VS S    +G+    +  DDG+FWM +  F++ F  + +C   N+    F++ Y E +  SEW+            +GGC NFK TF +NPQY FDI S +   V F L Q        N  + GL      + IG  ++KVE NRQYRVH   H +    S + +GRS++L L  L RGRY+ +P TF P +   FM R+YS   I+   LT+  P  G+     K  +  TR++I    F + S        G +  + ++ +++K   +    G    +WDE F+F++
Sbjct:   10 FGNQNYEKLRKICIKKKQPFVDTLFPPTNQSLF--------LEQRQSSDIVWKRPGELHPDPHLFVEGASPNDVTQGILGNCWFVSACSALTHNFKLLAQVIPDADDQEWST--KHAYAGIFRFRFWRFGKWVEVVIDDLLPTRDGKLLFARSKTPNEFWSALLEKAFAKLYGCYENLVGGHLSDALQDVSGGVAETLHVR-KFLKDDPNDTELKLFNDLKTAFDKGALVVAAIAARTKEEIEESLDCGLVKGHAYAVSAVCTIDVTNPNERSFTSFIMG--SKRKQNLIRLQNPWGEKEWNGAWSDDSPEWQNVSASQLSTMGVQPANSDSDDGDFWMPWESFVHYFTDISLCQLFNTSVFSFSRSYDEQIVFSEWTTNGKKSGAPDDRAGGCHNFKATFCNNPQYIFDIPSPNC-SVMFALIQ--------NDPSEGLKKREPFVTIGMHVMKVENNRQYRVHTAMHPI--AISDYASGRSVYLHLQSLPRGRYLLIPTTFAPKEQTLFMLRVYSDEHIHFSPLTKHAPKLGLLK--CKSAQSVTRLTIHGVDFNSAST-------GTHNVYAILKDSRKSFRTKTLSGVKSIQWDEQFLFHK 581          

Query:  192 NYTKIKSQLLETNTMFTDKEFPPNLTSLFSTLSNYDLTQNEELNNIRWRRPGQICENPYLFVNGVSTNDVLQGRLGNCWFVAACTCITVYRENWMMLIPDYKSQEWTKEDKSEYCGIFKFRFWKYGQWTEVVIDDQLPTLENDLIYCHSNYRNEFWSALLEKAYAKILGSYEALEGGELIESLVDFTGGLAEPIVITDDHLKPDKSSKLFQYLLKEHGNKSLIAAAIPAMTPEEQEEETSMGLIIGHAYAITMVIDLPVDTSKSDLKLVQSKVSNGHIRMMRLRNPWGQG-EWKGPFCDGSPEWDVVSKSSRHRVGLTFQDDGEFWMTFIDFLNNFKSVVICHQINSIFNKV---------------YYESVFHSEWS--KGFSGGCLNFKNTFLDNPQYA------FDINSADGE-EVQFCLTQKMIRELNRNGGATGLLHIGYSILKVEANRQYRVHRLDHCLLEQSSAFKNGRSIFLRLHLKRGRYIAVPCTFQPGQIQSFMFRIYSKNSINTGEL 1673
            N+ + + + L+   +F D +FP N +SL+     Y    +E    I W+RPG+I ENP L V   S  DV QG LG+CW +AA   +T+  E +  ++P    Q +T+     Y GIF F+FW+YGQW +VVIDD+LPT++  L Y  S   NEFWSALLEKAYAK+ G YE L+GG   E+L DFTGGL E   I+    K DKS+ L   L++     SL   +I A     +E + + GL+ GHAY+IT +  +                  G + ++R+RNPWG   EW G + DGS EW  V    R ++G+ F  DGEFWM+F DF+ NF  +  C+    + +++               + E     EW+  +G +GGC N  +T+ +NPQY        D    DG+  V   + QK  REL   G     L IG+S+ K + + Q          + ++  F N R + +R  +  G+Y+ VPCTF      SF+ RI+S     T  L
Sbjct:  296 NFQQERQRCLDQRCLFEDPQFPANDSSLY-----YKTRPDEP---IIWKRPGEIYENPQLIVGEKSRFDVKQGALGDCWLLAAVANLTLRDELFYRVVP--PDQSFTEN----YAGIFHFQFWRYGQWVDVVIDDRLPTVDGRLCYMRSQENNEFWSALLEKAYAKLYGGYENLDGGTTAEALEDFTGGLTEFFDIS----KGDKSTTL-AMLVRGMQMGSLFGCSIDA-DENVKEAQLTNGLVRGHAYSITAIQTV--------------NTYGGQVPLLRIRNPWGNSKEWNGAWSDGSSEWSQVDPQQREQMGVQFAKDGEFWMSFDDFMTNFTQMECCNLSADVMDEISEMTGVEVHDKQKHQWVEKSEDGEWNSRQGTAGGCQN-NDTYCNNPQYGTYFQVPMDSVEHDGKCTVIGAVLQKYRRELRTKG--LDNLPIGFSVYKADGSGQAIHDVSGQKPIARTKVFINMREVTVRFRVPPGQYVIVPCTFDAHDDASFLLRIFSNAEFQTTRL 777          

Query:  192 NYTKIKSQLLETNTMFTDKEFPPNLTSLFSTLSNYDLTQNEELNNIRWRRPGQICENPYLFVNGVSTNDVLQGRLGNCWFVAACTCITVYRENWMMLIPDYKSQEWTKEDKSEYCGIFKFRFWKYGQWTEVVIDDQLPTLENDLIYCHSNYRNEFWSALLEKAYAKILGSYEALEGGELIESLVDFTGGLAEPIVITDDHLKPDKSSKLFQYLLKEHGNKSLIAAAIPAMTPEEQEEETSMGLIIGHAYAITMVIDLPVDTSKSDLKLVQSKVSNGHIRMMRLRNPWGQG-EWKGPFCDGSPEWDVVSKSSRHRVGLTFQDDGEFWMTFIDFLNNFKSVVICHQINSIFNKV---------------YYESVFHSEWS--KGFSGGCLNFKNTFLDNPQYA------FDINSADGE-EVQFCLTQKMIRELNRNGGATGLLHIGYSILKVEANRQYRVHRLDHCLLEQSSAFKNGRSIFLRLHLKRGRYIAVPCTFQPGQIQSFMFRIYSKNSINTGEL 1673
            N+ + + + L+   +F D +FP N +SL+     Y    +E    I W+RPG+I ENP L V   S  DV QG LG+CW +AA   +T+  E +  ++P    Q +T+     Y GIF F+FW+YGQW +VVIDD+LPT++  L Y  S   NEFWSALLEKAYAK+ G YE L+GG   E+L DFTGGL E   I+    K DKS+ L   L++     SL   +I A     +E + + GL+ GHAY+IT +  +                  G + ++R+RNPWG   EW G + DGS EW  V    R ++G+ F  DGEFWM+F DF+ NF  +  C+    + +++               + E     EW+  +G +GGC N  +T+ +NPQY        D    DG+  V   + QK  REL   G     L IG+S+ K + + Q          + ++  F N R + +R  +  G+Y+ VPCTF      SF+ RI+S     T  L
Sbjct:  296 NFQQERQRCLDQRCLFEDPQFPANDSSLY-----YKTRPDEP---IIWKRPGEIYENPQLIVGEKSRFDVKQGALGDCWLLAAVANLTLRDELFYRVVP--PDQSFTEN----YAGIFHFQFWRYGQWVDVVIDDRLPTVDGRLCYMRSQENNEFWSALLEKAYAKLYGGYENLDGGTTAEALEDFTGGLTEFFDIS----KGDKSTTL-AMLVRGMQMGSLFGCSIDA-DENVKEAQLTNGLVRGHAYSITAIQTV--------------NTYGGQVPLLRIRNPWGNSKEWNGAWSDGSSEWSQVDPQQREQMGVQFAKDGEFWMSFDDFMTNFTQMECCNLSADVMDEISEMTGVEVHDKQKHQWVEKSEDGEWNSRQGTAGGCQN-NDTYCNNPQYGTYFQVPMDSVEHDGKCTVIGAVLQKYRRELRTKG--LDNLPIGFSVYKADGSGQAIHDVSGQKPIARTKVFINMREVTVRFRVPPGQYVIVPCTFDAHDDASFLLRIFSNAEFQTTRL 777          

Query:  207 KSQLLETNTMFTDKEFPPNLTSLFSTLSNYDLTQNEELNNIRWRRPGQICENPYLFVNGVSTNDVLQGRLGNCWFVAACTCITVYRENWMMLIPDYKSQEWTKEDKSEYCGIFKFRFWKYGQWTEVVIDDQLPTLENDLIYCHSNYRNEFWSALLEKAYAKILGSYEALEGGELIESLVDFTGGLAEPIVITDDHLKPDKSSKLFQYLLKEHGNKSLIAAAIPAMTPEEQEEETSMGLIIGHAYAITMVIDLPVDTSKSDLKLVQSKVSNGHIRMMRLRNPWG-QGEWKGPFCDGSPEWDVVSKSSRHRVGLTFQDDGEFWMTFIDFLNNFKSVVICHQINSIFNKV------------------YYESVFHSEWS--KGFSGGCLNFKNTFLDNPQYAFDINS------ADGE-EVQFCLTQKMIRELNRNGGATGLLHIGYSILKVEANRQYRVHRLDHCL-----LEQSSAFKNGRSIFLRLHLKRGRYIAVPCTFQPGQIQSFMFRIYSKNSINTGEL 1673
            + + L   T+F D EFP    SL+      D         I W+RPG+I  NP L   G S  DV QG LG+CWF+AA   IT+Y   +  ++P   +Q +T+     Y GIF F+FW YG+W +VV+DD+LPT+ N L Y HS    EFWSAL+EKAYAK+ G YE L+GG   E+L DFTGGL E        L+  + + +   L+K     SL   +I A     +E +   GL+ GHAY+IT +  +      + L              +RLRNPWG + EW G + DGS EW  + ++++ ++ + F  DGEFWM+F DF +NF  + +C+    IF+++                  ++E +   EWS  KG +GGC N  +T+  NPQ++    +      ADG   V   + QK  REL   G    +L IG SI  + A    R             + +++ F N R + +R  +  G+Y+ VPCTF       F+ R+Y+  ++ +  L
Sbjct:  231 REKCLRNKTLFEDPEFPATAASLYYRTPPRD--------RIIWKRPGEIIANPQLITQGESRFDVKQGALGDCWFLAALANITLYDALFYRIVP--PNQSFTEN----YAGIFHFQFWHYGKWVDVVVDDRLPTVNNQLYYLHSADNTEFWSALVEKAYAKLHGGYENLDGGTTAEALEDFTGGLTEYF-----DLRKSEKAAVLAALVKGMEMGSLFGCSIDA-DANIKEAQLRNGLVCGHAYSITAIHSITYYGEDTTL--------------LRLRNPWGNEKEWNGAWSDGSSEWSKIDEATKKQIDVQFARDGEFWMSFEDFFSNFTQMEVCNLTAEIFDEIAEMTGVNRATETVEEEHQWHEIMEDGEWSSKKGTAGGCNNNPSTYPKNPQFSTFFTAPQSSIEADGNVTVIVAVLQKYRRELRSKG--KDVLPIGVSIYSLGAEGTARSPLTAQFFSQNRPIARTTVFVNTREVTVRFRVPPGQYVIVPCTFDAYDDAEFLLRVYANGTLKSSLL 716          

Query:  189 QNYTKIKSQLLETNTMFTDKEFPPNLTSLFSTLSNYDLTQNEELNNIRWRRPGQICENPYLFVNGVSTNDVLQGRLGNCWFVAACTCITVYRENWMMLIPDYKSQEWTKEDKSEYCGIFKFRFWKYGQWTEVVIDDQLPTLENDLIYCHSNYRNEFWSALLEKAYAKILGSYEALEGGELIESLVDFTGGLAEPIVITDDHLKPDKSSKLFQYLLKEHGNKSLIAAAIPAMTPEEQEEETSMGLIIGHAYAIT--MVIDLPVDTSKSDLKLVQSKVSNGHIRMMRLRNPWG-QGEWKGPFCDGSPEWDVVSKSSRHRVGLTFQDDGEFWMTFIDFLNNFKSVVICHQINSIFNKVY------------YESVFHSEWSKG-FSGGCLNFKNTFLDNPQYAFDINSADGEE------VQFCLTQKMIRELNRNGGATGLLHIGYSILKVEANRQYRVHRLDHCLLE------QSSAFKNGRSIFLRLHLKRGRYIAVPCTFQPGQIQSFMFRIYSKNSINTGEL 1673
            Q++ +++ Q LE+  +F D +F  N +SLF +              + W RPG+I   P L   G S  DV+QG LG+CW +AA   +T+  E +  ++P    Q +T+     Y GIF F+FW+YG+W +VVIDD+LPT   +L+Y HS   NEFWSALLEKAYAK+ GSYEAL+GG   E+L D TGGL E I    D   P ++  L Q +++     SL   +I A  P   E + S GL+ GHAY+IT   ++D P                NG   ++R+RNPWG + EW GP+ D S EW  V  S +  +GL F  DGEFWM+F DF+ NF+ + IC+    + ++VY              +     W +   +GGC N+ NTF +NPQ+   +  +D ++      V F + QK  R L ++G     + IG+++     NR     RL            +S+AF N R +  R  +  G Y+ VP TF+P +   FM R+Y+   I + EL
Sbjct:  280 QDFYELRDQCLESKRLFEDPQFLANDSSLFFS--------KRPPKRVEWLRPGEITREPQLITEGHSRFDVIQGELGDCWLLAAAANLTLKDELFYRVVP--PDQSFTEN----YAGIFHFQFWQYGKWVDVVIDDRLPTSNGELLYMHSASNNEFWSALLEKAYAKLFGSYEALKGGTTSEALEDMTGGLTEFI----DLKNPPRN--LMQMMMRGFEMGSLFGCSIEA-DPNVWEAKMSNGLVKGHAYSITGCRIVDGP----------------NGQTCILRIRNPWGNEQEWNGPWSDNSREWRSVPDSVKQDMGLKFDHDGEFWMSFDDFMRNFEKMEICNLGPDVMDEVYQMTGVKAAGMVWAANTHDGAWVRNQTAGGCRNYINTFANNPQFRVQLTDSDPDDDDELCTVIFAVLQKYRRNLKQDGLDN--VPIGFAVYDAGNNR----GRLSKQFFAANKSAMRSAAFINLREMTGRFRVPPGNYVVVPSTFEPNEEAEFMLRVYTNGFIESEEL 759          

Query:  189 QNYTKIKSQLLETNTMFTDKEFPPNLTSL-FSTLSNYDLTQNEELNNIRWRRPGQICENPYLFVNGVSTNDVLQGRLGNCWFVAACTCITVYRENWMMLIPDYKSQEWTKEDKSEYCGIFKFRFWKYGQWTEVVIDDQLPTLENDLIYCHSNYRNEFWSALLEKAYAKILGSYEALEGGELIESLVDFTGGLAEPIVITDDHLKPDKSSKLFQYLLKEHGNKSLIAAAIPAMTPEEQEEETSMGLIIGHAYAITMVIDLPVDTSKSDLKLVQSKVSNGHIRMMRLRNPWG-QGEWKGPFCDGSPEWDVVSKSSRHRVGLTFQDDGEFWMTFIDFLNNFKSVVICH---------QINSIFNKVYYESVFHSEWSKGF-SGGCLNFKNTFLDNPQYAFDINSAD--GEEVQFCLTQKMIRELNRNGGATGL--LHIGYSILKV-EANRQYRVHRLD----HCLLEQSSAFKNGRSIFLRLHLKRGRYIAVPCTFQPGQIQSFMFRIYSKNSIN 1661
            Q+Y  I +  L + ++F D  FP +  SL FS   +          +I W RP +I ENP  FV G S  DV QG LG+CW +AA   +T     +  +IP  +S E        Y GIF FRFW+YG+W +V+IDD+LPT   +L+Y HS  +NEFWSALLEKAYAK+ GSYEAL+GG   E++ DFTGG++E   +       +    LF  L K     S++  +I    P   E ET  GLI GHAY+IT V  + + T              G I M+R+RNPWG + EW GP+ D SPEW  + +  +  +GLTF  DGEFWM+F DFLN+F  V IC+         Q NS   K +  S++  EW+ G  +GGC NF +TF  NPQY   +   D   EE Q  +   ++++  R+    G+  L IG++I  + +   + R   L+       + +S  F N R +  R  L  G Y+ VP TF P +   F+ R++S+   N
Sbjct:   73 QDYETILNSCLASGSLFEDPLFPASNESLQFSRRPD---------RHIEWLRPHEIAENPQFFVEGYSRFDVQQGELGDCWLLAATANLTQESNLFFRVIPAEQSFE------ENYAGIFHFRFWQYGKWVDVIIDDRLPTYNGELMYMHSTEKNEFWSALLEKAYAKLHGSYEALKGGSTCEAMEDFTGGVSEWYDLK------EAPGNLFTILQKAAERNSMMGCSIEP-DPNVTEAETPQGLIRGHAYSITKVCLIDIVTPN----------RQGKIPMIRMRNPWGNEAEWNGPWSDSSPEWRYIPEEQKAEIGLTFDRDGEFWMSFQDFLNHFDRVEICNLSPDSLTEDQQNSGKRK-WEMSMYEGEWTPGVTAGGCRNFLDTFWHNPQYIITLVDPDEEDEEGQCTVIVALMQKNRRSKRNMGMECLTIGFAIYSLNDRELENRPQGLNFFRYKSSVGRSPHFINTREVCARFKLPPGHYLIVPSTFDPNEEGEFIIRVFSETQNN 551          

Query:  189 QNYTKIKSQLLETNTMFTDKEFPPNLTSL-FSTLSNYDLTQNEELNNIRWRRPGQICENPYLFVNGVSTNDVLQGRLGNCWFVAACTCITVYRENWMMLIPDYKSQEWTKEDKSEYCGIFKFRFWKYGQWTEVVIDDQLPTLENDLIYCHSNYRNEFWSALLEKAYAKILGSYEALEGGELIESLVDFTGGLAEPIVITDDHLKPDKSSKLFQYLLKEHGNKSLIAAAIPAMTPEEQEEETSMGLIIGHAYAITMVIDLPVDTSKSDLKLVQSKVSNGHIRMMRLRNPWG-QGEWKGPFCDGSPEWDVVSKSSRHRVGLTFQDDGEFWMTFIDFLNNFKSVVICH---------QINSIFNKVYYESVFHSEWSKGF-SGGCLNFKNTFLDNPQYAFDINSADGEE------VQFCLTQKMIRELNRNGGATGLLHIGYSILKV-EANRQYRVHRLD----HCLLEQSSAFKNGRSIFLRLHLKRGRYIAVPCTFQPGQIQSFMFRIYSKNSINTGE 1670
            Q+Y  I +  L + ++F D  FP +  SL FS   +          +I W RP +I ENP  FV G S  DV QG LG+CW +AA   +T     +  +IP  +S E        Y GIF FRFW+YG+W +V+IDD+LPT   +L+Y HS  +NEFWSALLEKAYAK+ GSYEAL+GG   E++ DFTGG++E   +       +    LF  L K     S++  +I    P   E ET  GLI GHAY+IT V  + + T              G I M+R+RNPWG + EW GP+ D SPEW  + +  +  +GLTF  DGEFWM+F DFLN+F  V IC+         Q NS   K +  S++  EW+ G  +GGC NF +TF  NPQY   +   D E+      V   L QK  R   RN G    L IG++I  + +   + R   L+       + +S  F N R +  R  L  G Y+ VP TF P +   F+ R++S+   N  E
Sbjct:   73 QDYETILNSCLASGSLFEDPLFPASNESLQFSRRPD---------RHIEWLRPHEIAENPQFFVEGYSRFDVQQGELGDCWLLAATANLTQESNLFFRVIPAEQSFE------ENYAGIFHFRFWQYGKWVDVIIDDRLPTYNGELMYMHSTEKNEFWSALLEKAYAKLHGSYEALKGGSTCEAMEDFTGGVSEWYDLK------EAPGNLFTILQKAAERNSMMGCSIEP-DPNVTEAETPQGLIRGHAYSITKVCLIDIVTPN----------RQGKIPMIRMRNPWGNEAEWNGPWSDSSPEWRYIPEEQKAEIGLTFDRDGEFWMSFQDFLNHFDRVEICNLSPDSLTEDQQNSGKRK-WEMSMYEGEWTPGVTAGGCRNFLDTFWHNPQYIITLVDPDEEDEEGQCTVIVALMQKN-RRSKRNMGME-CLTIGFAIYSLNDRELENRPQGLNFFRYKSSVGRSPHFINTREVCARFKLPPGHYLIVPSTFDPNEEGEFIIRVFSETQNNMEE 554          

Query:  189 QNYTKIKSQLLETNTMFTDKEFPPNLTSL-FSTLSNYDLTQNEELNNIRWRRPGQICENPYLFVNGVSTNDVLQGRLGNCWFVAACTCITVYRENWMMLIPDYKSQEWTKEDKSEYCGIFKFRFWKYGQWTEVVIDDQLPTLENDLIYCHSNYRNEFWSALLEKAYAKILGSYEALEGGELIESLVDFTGGLAEPIVITDDHLKPDKSSKLFQYLLKEHGNKSLIAAAIPAMTPEEQEEETSMGLIIGHAYAITMVIDLPVDTSKSDLKLVQSKVSNGHIRMMRLRNPWG-QGEWKGPFCDGSPEWDVVSKSSRHRVGLTFQDDGEFWMTFIDFLNNFKSVVICH---------QINSIFNKVYYESVFHSEWSKGF-SGGCLNFKNTFLDNPQYAFDINSADGEE------VQFCLTQKMIRELNRNGGATGLLHIGYSILKV-EANRQYRVHRLD----HCLLEQSSAFKNGRSIFLRLHLKRGRYIAVPCTFQPGQIQSFMFRIYSKNSINTGE 1670
            Q+Y  I +  L + ++F D  FP +  SL FS   +          +I W RP +I ENP  FV G S  DV QG LG+CW +AA   +T     +  +IP  +S E        Y GIF FRFW+YG+W +V+IDD+LPT   +L+Y HS  +NEFWSALLEKAYAK+ GSYEAL+GG   E++ DFTGG++E   +       +    LF  L K     S++  +I    P   E ET  GLI GHAY+IT V  + + T              G I M+R+RNPWG + EW GP+ D SPEW  + +  +  +GLTF  DGEFWM+F DFLN+F  V IC+         Q NS   K +  S++  EW+ G  +GGC NF +TF  NPQY   +   D E+      V   L QK  R   RN G    L IG++I  + +   + R   L+       + +S  F N R +  R  L  G Y+ VP TF P +   F+ R++S+   N  E
Sbjct:   73 QDYETILNSCLASGSLFEDPLFPASNESLQFSRRPD---------RHIEWLRPHEIAENPQFFVEGYSRFDVQQGELGDCWLLAATANLTQESNLFFRVIPAEQSFE------ENYAGIFHFRFWQYGKWVDVIIDDRLPTYNGELMYMHSTEKNEFWSALLEKAYAKLHGSYEALKGGSTCEAMEDFTGGVSEWYDLK------EAPGNLFTILQKAAERNSMMGCSIEP-DPNVTEAETPQGLIRGHAYSITKVCLIDIVTPN----------RQGKIPMIRMRNPWGNEAEWNGPWSDSSPEWRYIPEEQKAEIGLTFDRDGEFWMSFQDFLNHFDRVEICNLSPDSLTEDQQNSGKRK-WEMSMYEGEWTPGVTAGGCRNFLDTFWHNPQYIITLVDPDEEDEEGQCTVIVALMQKN-RRSKRNMGME-CLTIGFAIYSLNDRELENRPQGLNFFRYKSSVGRSPHFINTREVCARFKLPPGHYLIVPSTFDPNEEGEFIIRVFSETQNNMEE 554          

Query:  189 QNYTKIKSQLLETNTMFTDKEFPPNLTSL-FSTLSNYDLTQNEELNNIRWRRPGQICENPYLFVNGVSTNDVLQGRLGNCWFVAACTCITVYRENWMMLIPDYKSQEWTKEDKSEYCGIFKFRFWKYGQWTEVVIDDQLPTLENDLIYCHSNYRNEFWSALLEKAYAKILGSYEALEGGELIESLVDFTGGLAEPIVITDDHLKPDKSSKLFQYLLKEHGNKSLIAAAIPAMTPEEQEEETSMGLIIGHAYAITMVIDLPVDTSKSDLKLVQSKVSNGHIRMMRLRNPWG-QGEWKGPFCDGSPEWDVVSKSSRHRVGLTFQDDGEFWMTFIDFLNNFKSVVICH---------QINSIFNKVYYESVFHSEWSKGF-SGGCLNFKNTFLDNPQYAFDINSADGEE------VQFCLTQKMIRELNRNGGATGLLHIGYSILKV-EANRQYRVHRLD----HCLLEQSSAFKNGRSIFLRLHLKRGRYIAVPCTFQPGQIQSFMFRIYSKNSINTGE 1670
            Q+Y  I +  L + ++F D  FP +  SL FS   +          +I W RP +I ENP  FV G S  DV QG LG+CW +AA   +T     +  +IP  +S E        Y GIF FRFW+YG+W +V+IDD+LPT   +L+Y HS  +NEFWSALLEKAYAK+ GSYEAL+GG   E++ DFTGG++E   +       +    LF  L K     S++  +I    P   E ET  GLI GHAY+IT V  + + T              G I M+R+RNPWG + EW GP+ D SPEW  + +  +  +GLTF  DGEFWM+F DFLN+F  V IC+         Q NS   K +  S++  EW+ G  +GGC NF +TF  NPQY   +   D E+      V   L QK  R   RN G    L IG++I  + +   + R   L+       + +S  F N R +  R  L  G Y+ VP TF P +   F+ R++S+   N  E
Sbjct:   88 QDYETILNSCLASGSLFEDPLFPASNESLQFSRRPD---------RHIEWLRPHEIAENPQFFVEGYSRFDVQQGELGDCWLLAATANLTQESNLFFRVIPAEQSFE------ENYAGIFHFRFWQYGKWVDVIIDDRLPTYNGELMYMHSTEKNEFWSALLEKAYAKLHGSYEALKGGSTCEAMEDFTGGVSEWYDLK------EAPGNLFTILQKAAERNSMMGCSIEP-DPNVTEAETPQGLIRGHAYSITKVCLIDIVTPN----------RQGKIPMIRMRNPWGNEAEWNGPWSDSSPEWRYIPEEQKAEIGLTFDRDGEFWMSFQDFLNHFDRVEICNLSPDSLTEDQQNSGKRK-WEMSMYEGEWTPGVTAGGCRNFLDTFWHNPQYIITLVDPDEEDEEGQCTVIVALMQKN-RRSKRNMGME-CLTIGFAIYSLNDRELENRPQGLNFFRYKSSVGRSPHFINTREVCARFKLPPGHYLIVPSTFDPNEEGEFIIRVFSETQNNMEE 569          

Query:  192 NYTKIKSQLLETNTMFTDKEFPPNLTSLFSTLSNYDLTQNEELNNIRWRRPGQICENPYLFVNGVSTNDVLQGRLGNCWFVAACTCITVYRENWMMLIP-DYKSQEWTKEDKSEYCGIFKFRFWKYGQWTEVVIDDQLPTLENDLIYCHSNYRNEFWSALLEKAYAKILGSYEALEGGELIESLVDFTGGLAEPIVITDDHLKPDKSSKLFQYLLKEHGNKSLIAAAIPAMTPEEQEEETSMGLIIGHAYAITMVIDLPVDTSKSDLKLVQSKVSNGHIRMMRLRNPWG-QGEWKGPFCDGSPEWDVVSKSSRHRVGLTFQDDGEFWMTFIDFLNNFKSVVICH---------QINSIFNKVYYESVFHSEWSKGF-SGGCLNFKNTFLDNPQYAFDI-----NSADGEEVQFCLTQKMIRELNRNGGATGLLHIGYSILKV-EANRQYRVHRLD----HCLLEQSSAFKNGRSIFLRLHLKRGRYIAVPCTFQPGQIQSFMFRIYSKNSINTGELTQSLPSPGMSNYLVKVPEVATRISIFKAISLPRLDPIHGANPFFVLICENQKCISSICHGTMEPEWDE 1877
            ++  ++   L   TMF D +FP    SL        +          W RPG I ++P  FV G S  DV QG LG+CW +AA   +T     +  +IP D   QE        Y GIF F+FW+YG+W EVVIDD+LPT   +LIY HS  +NEFWSALLEKAYAK+ GSYEAL+GG   E++ DFTGG+ E   I       +    LF  ++K     S++  ++    P   E ET  GLI GHAY+IT V  + + T              G + M+R+RNPWG   EW GP+ D SPEW  + + ++  +GL F  DGEFWM+F DFLN+F  V IC+         Q +S   K +  S+F  EW+ G  +GGC NF  TF  NPQY   +        DG+        +  R   RN G    L IG++I  + + + Q +   L+       + +S  F N R +  R  L  G Y+ VP TF P +   F+ R++S+   N  E          ++  V   E   RI    A SLP   P    +P  + +   ++   S+     E +W E
Sbjct:  245 DFQSLRDSCLANGTMFEDPDFPATNASL--------MYSRRPDRYYEWLRPGDIADDPQFFVEGYSRFDVQQGELGDCWLLAAAANLTQDSTLFFRVIPPDQDFQE-------NYAGIFHFKFWQYGKWVEVVIDDRLPTYNGELIYMHSTEKNEFWSALLEKAYAKLHGSYEALKGGTTCEAMEDFTGGVTEWYDIK------EAPPNLFSIMMKAAERGSMMGCSL-EPDPHVLEAETPQGLIRGHAYSITKVCLMDISTPN----------RQGKLPMIRMRNPWGNDAEWSGPWSDSSPEWRFIPEHTKEEIGLNFDRDGEFWMSFQDFLNHFDRVEICNLSPDSLTEDQQHSSRRK-WEMSMFEGEWTSGVTAGGCRNFLETFWHNPQYIISLEDPDDEDDDGKCTAIVALMQKNRRSKRNVG-IDCLTIGFAIYHLTDRDMQVKPQGLNFFKYRASVARSPHFINTREVCARFKLPPGHYLIVPSTFDPNEEGEFIIRVFSETRNNMEE----------NDDEVGFGETDDRI----APSLPPPTPKEEDDPQRIAL---RRLFDSVAGSDEEVDWQE 777          

Query:  159 MFDKPILYKNQNYTKIKSQLLETNTMFTDKEFPPNLTSLFSTLSNYDLTQNEELNNIRWRRPGQICENPYLFVNGVSTNDVLQGRLGNCWFVAACTCITVYRENWMMLIPDYKSQEWTKEDKSEYCGIFKFRFWKYGQWTEVVIDDQLPTLENDLIYCHSNYRNEFWSALLEKAYAKILGSYEALEGGELIESLVDFTGGLAEPIVITDDHLKPDKSSK--LFQYLLKEHGNKSLIAAAIPAMTPEEQEEETSMGLIIGHAYAITMVIDLPVDTSKSDLKLVQSKVSNGHIRMMRLRNPWGQGEWKGPFCDGSPEWDVVSKSSRHRVGLTFQDDGEFWMTFIDFLNNFKSVVICHQINSIF---NKVYYESVFHSEW------SKGFSGGCLNFKNTFLDNPQYAFDINSADGEEVQFCLTQKMIRELNRNGGATGLLHIGYSILKVEANRQYRVHRLDHCLLEQSSAFKNGRSIFLRLHLKRGRYIAVPCTFQPGQIQSFMFRIYSKNSINTGELTQSLPSPGMSNYLVKVPEVATRISIFKAISLPRLDPIHGANPFFVLICENQKCISSICHGTMEPEWDESFIFYRKYFSKEPIVLLVYSRSGIIDEFIGKQAF--EGNGKEENQVLEFKLLGKKPDSVSHGSIFVQYKT 2081
            MF     ++ Q+Y+ +K Q L++  +F D  FP    SLF         Q   +  + W+RP ++C++P+LFV+G+S +D+ QG+LGNCWFVAAC+ +      W  +IPD+K QEW  E    Y GIF FRFW++G+W +VVIDD+LPT++N L+YCHSN  NEFWSAL+EKAYAK+ G YEAL+GG   ++LVDFTGG++EP+ + +     D++++  LF+ +LK H    LI+ +I A T E+ E     GL+ GHAYA+T V    V      L   +S+     + M+R+RNPWG+ EW GP+ D S EW  VSKS R ++G+T QDDGEFWM F DF + F  +++C  IN+ +   +K + E V    W       +  +GGC+N K TFL NPQY FD+   + +EV  CL QK  R   + G    L  IG+ I +VE NR+YR+H     +    S + N R +FLR  LK GRY+ +P TF PGQ   F+ R+++    +  ELT   P       +   P++ T++ +  A  L   D    ++P+ ++ CE +K  S +   T  P +D   IFYRK   KE I + +Y+++ I+D F+G+     + N ++E   +  K  G + D+   G++ V+  T
Sbjct:    1 MFSSAKAFEGQHYSTLKRQCLQSGALFEDPLFPAVDDSLF--------YQGNRIGRVHWKRPEELCDDPHLFVDGISAHDLHQGQLGNCWFVAACSSLASRESLWQKVIPDWKEQEWDPEKADSYAGIFHFRFWRFGEWVDVVIDDRLPTVDNQLVYCHSNDSNEFWSALVEKAYAKVYGCYEALDGGNTADALVDFTGGVSEPMDLLEGQFAQDETARNQLFERVLKVHNRDGLISCSIRATTVEDMEARLDCGLVKGHAYAVTDV--RKVRLGHGLLAYFKSE----KLHMIRMRNPWGEKEWSGPWSDSSEEWKKVSKSEREKLGVTVQDDGEFWMNFEDFCHYFTDLILCRLINTSYLSIHKTWEEEVMRGLWLHRDEPLRNRAGGCINHKTTFLQNPQYVFDVRKVE-DEVLICLQQKERRATPKEGKGENLA-IGFDIHRVELNRKYRMHSAQQKV--AGSIYINSRCVFLRKELKEGRYVIIPTTFDPGQQGEFLLRVFTDVPSDCKELTLDEPPQTCWTGMCGYPQLVTQVHVLSAEGLQGQDANGASDPYVIITCEGEKVRSPVHKDTRCPNFDIKGIFYRKK-PKEGIHIEIYNKNVIVDTFLGQVTLFSDPNDRQEQHTVYLKDKGSRQDNNLPGTLTVRVIT 635          

Query:  159 MFDKPILYKNQNYTKIKSQLLETNTMFTDKEFPPNLTSLFSTLSNYDLTQNEELNNIRWRRPGQICENPYLFVNGVSTNDVLQGRLGNCWFVAACTCITVYRENWMMLIPDYKSQEWTKEDKSEYCGIFKFRFWKYGQWTEVVIDDQLPTLENDLIYCHSNYRNEFWSALLEKAYAKILGSYEALEGGELIESLVDFTGGLAEPIVITDDHLKPDKSSK--LFQYLLKEHGNKSLIAAAIPAMTPEEQEEETSMGLIIGHAYAITMVIDLPVDTSKSDLKLVQSKVSNGHIRMMRLRNPWGQGEWKGPFCDGSPEWDVVSKSSRHRVGLTFQDDGEFWMTFIDFLNNFKSVVICHQINSIF---NKVYYESVFHSEW------SKGFSGGCLNFKNTFLDNPQYAFDINSADGEEVQFCLTQKMIRELNRNGGATGLLHIGYSILKVEANRQYRVHRLDHCLLEQSSAFKNGRSIFLRLHLKRGRYIAVPCTFQPGQIQSFMFRIYSKNSINTGELTQSLPSPGMSNYLVKVPEVATRISIFKAISLPRLDPIHGANPFFVLICENQKCISSICHGTMEPEWDESFIFYRKYFSKEPIVLLVYSRSGIIDEFIGKQAF--EGNGKEENQVLEFKLLGKKPDSVSHGSIFVQYKT 2081
            MF     ++ Q+Y+ +K Q L++  +F D  FP    SLF         Q   +  + W+RP ++C++P+LFV+G+S +D+ QG+LGNCWFVAAC+ +      W  +IPD+K QEW  E    Y GIF FRFW++G+W +VVIDD+LPT++N L+YCHSN  NEFWSAL+EKAYAK+ G YEAL+GG   ++LVDFTGG++EP+ + +     D++++  LF+ +LK H    LI+ +I A T E+ E     GL+ GHAYA+T V    V      L   +S+     + M+R+RNPWG+ EW GP+ D S EW  VSKS R ++G+T QDDGEFWM F DF + F  +++C  IN+ +   +K + E V    W       +  +GGC+N K TFL NPQY FD+   + +EV  CL QK  R   + G    L  IG+ I +VE NR+YR+H     +    S + N R +FLR  LK GRY+ +P TF PGQ   F+ R+++    +  ELT   P       +   P++ T++ +  A  L   D    ++P+ ++ CE +K  S +   T  P +D   IFYRK   +   + + +  + I+D F+G+     + N ++E   +  K  G + D+   G++ V+  T
Sbjct:    1 MFSSAKAFEGQHYSTLKRQCLQSGALFEDPLFPAVDDSLF--------YQGNRIGRVHWKRPEELCDDPHLFVDGISAHDLHQGQLGNCWFVAACSSLASRESLWQKVIPDWKEQEWDPEKADSYAGIFHFRFWRFGEWVDVVIDDRLPTVDNQLVYCHSNDSNEFWSALVEKAYAKVYGCYEALDGGNTADALVDFTGGVSEPMDLLEGQFAQDETARNQLFERVLKVHNRDGLISCSIRATTVEDMEARLDCGLVKGHAYAVTDV--RKVRLGHGLLAYFKSE----KLHMIRMRNPWGEKEWSGPWSDSSEEWKKVSKSEREKLGVTVQDDGEFWMNFEDFCHYFTDLILCRLINTSYLSIHKTWEEEVMRGLWLHRDEPLRNRAGGCINHKTTFLQNPQYVFDVRKVE-DEVLICLQQKERRATPKEGKGENLA-IGFDIHRVELNRKYRMHSAQQKV--AGSIYINSRCVFLRKELKEGRYVIIPTTFDPGQQGEFLLRVFTDVPSDCKELTLDEPPQTCWTGMCGYPQLVTQVHVLSAEGLQGQDANGASDPYVIITCEGEKVRSPVHKDTRCPNFDIKGIFYRKKPKEGIHIEVSWKYNVIVDTFLGQVTLFSDPNDRQEQHTVYLKDKGSRQDNNLPGTLTVRVIT 636          

Query:  159 MFDKPILYKNQNYTKIKSQLLETNTMFTDKEFPPNLTSLFSTLSNYDLTQNEELNNIRWRRPGQICENPYLFVNGVSTNDVLQGRLGNCWFVAACTCITVYRENWMMLIPDYKSQEWTKEDKSEYCGIFKFRFWKYGQWTEVVIDDQLPTLENDLIYCHSNYRNEFWSALLEKAYAKILGSYEALEGGELIESLVDFTGGLAEPIVITDDHLKPDKSSK--LFQYLLKEHGNKSLIAAAIPAMTPEEQEEETSMGLIIGHAYAITMVIDLPVDTSKSDLKLVQSKVSNGHIRMMRLRNPWGQGEWKGPFCDGSPEWDVVSKSSRHRVGLTFQDDGEFWMTFIDFLNNFKSVVICHQINSIF---NKVYYESVFHSEWS------KGFSGGCLNFKNTFLDNPQYAFDINSADGEEVQFCLTQKMIRELNRNGGATGLLHIGYSILKVEANRQYRVHRLDHCLLEQSSAFKNGRSIFLRLHLKRGRYIAVPCTFQPGQIQSFMFRIYSKNSINTGELTQSLPSPGMSNYLVKVPEVATRISIFKAISLPRLDPIHGANPFFVLICENQKCISSICHGTMEPEWDESFIFYRKYFSKEPIVLLVYSRSGIIDEFIGKQAFEGNGKEENQVLEFKLLGK 2033
            MF     ++ Q ++ ++ Q  + +T+F D  F     SLF         Q   L  + W+RP  +CE+P+LFVNG+S +D+ QG+LGNCWFVAAC+ +      W  +IPD+K QEW K     Y GIF FRFW++G W +VVIDD+LPT    LIYCHSN  NEFWSAL+EKAYAK+ G YEAL+GG   ++LVDFTGG++EP+ + +     D+ ++  LF  +LK H    LI+ +I A T  + E     GL+ GHAYA+T V  + + +    L   +S+     + M+R+RNPWGQ EW G + D S EW  VSK  R R+G+T +DDGEFWM F DF  +F  +++C  IN+ +   +K + E V    WS      +  SGGC+N K TFL NPQY FD+  A+ +EV  CL Q+  R   R  G    + IG+ I +VE NR YR+H +   +   SS + N RS+FLR  LK GRY+ VP TF PG    F+ RI++    +  ELT   P           P++ T++ + +A  L  LD    ++P+ ++ CE +K  S +   T  P++D   +FYRK   K+PI + +Y+++ + D F+G+    G+  +  Q+   +L  K
Sbjct:    1 MFSSVKPFEGQEFSALRKQCQQNHTLFEDPVFRAEDQSLF--------LQGNRLGKVTWKRPKDLCEDPHLFVNGISAHDLNQGQLGNCWFVAACSSLASREALWQKVIPDWKDQEWDKNKPESYAGIFHFRFWRFGDWVDVVIDDRLPTANGKLIYCHSNDSNEFWSALVEKAYAKMCGCYEALDGGNTADALVDFTGGVSEPMDLLEGKFAQDEEARHQLFDRVLKVHNRGGLISCSIRATTQADMEARLDCGLVKGHAYAVTDVRKVRLGSGL--LAFFKSE----KLSMIRMRNPWGQREWNGAWSDSSEEWKRVSKGERERLGVTVEDDGEFWMDFDDFCKHFTDLILCRLINTSYLSIHKTWEEEVMRGCWSRHDDPLRNRSGGCINHKTTFLQNPQYVFDVTKAE-DEVLICLQQQDKRA--RAKGEN--MAIGFDIQRVELNRIYRMHSIQKSV--GSSIYINSRSVFLRKDLKEGRYVIVPSTFDPGMPGDFLLRIFTDVPSDCKELTVDEPPQTCWTSCCGYPKLVTQVHVIRADGLKALDGDGSSDPYIIISCEGEKVCSPVHKDTQSPDFDVKAVFYRKK-PKQPIRIQIYNKNLLSDSFMGQVTLNGDLSDLQQLHTLRLQDK 614          

Query:  159 MFDKPILYKNQNYTKIKSQLLETNTMFTDKEFPPNLTSLFSTLSNYDLTQNEELNNIRWRRPGQICENPYLFVNGVSTNDVLQGRLGNCWFVAACTCITVYRENWMMLIPDYKSQEWTKEDKSEYCGIFKFRFWKYGQWTEVVIDDQLPTLENDLIYCHSNYRNEFWSALLEKAYAKILGSYEALEGGELIESLVDFTGGLAEPIVITDDHLKPDKSSK--LFQYLLKEHGNKSLIAAAIPAMTPEEQEEETSMGLIIGHAYAITMVIDLPVDTSKSDLKLVQSKVSNGHIRMMRLRNPWGQGEWKGPFCDGSPEWDVVSKSSRHRVGLTFQDDGEFWMTFIDFLNNFKSVVICHQINSIF---NKVYYESVFHSEWS------KGFSGGCLNFKNTFLDNPQYAFDINSADGEEVQFCLTQKMIRELNRNGGATGLLHIGYSILKVEANRQYRVHRLDHCLLEQSSAFKNGRSIFLRLHLKRGRYIAVPCTFQPGQIQSFMFRIYSKNSINTGELTQSLPSPGMSNYLVKVPEVATRISIFKAISLPRLDPIHGANPFFVLICENQKCISSICHGTMEPEWDESFIFYRKYFSKEPIVLLVYSRSGIIDEFIGKQAFEGNGKEENQVLEFKLLGK 2033
            MF     ++ Q ++ ++ Q  + +T+F D  F     SLF         Q   L  + W+RP  +CE+P+LFVNG+S +D+ QG+LGNCWFVAAC+ +      W  +IPD+K QEW K     Y GIF FRFW++G W +VVIDD+LPT    LIYCHSN  NEFWSAL+EKAYAK+ G YEAL+GG   ++LVDFTGG++EP+ + +     D+ ++  LF  +LK H    LI+ +I A T  + E     GL+ GHAYA+T V  + + +    L   +S+     + M+R+RNPWGQ EW G + D S EW  VSK  R R+G+T +DDGEFWM F DF  +F  +++C  IN+ +   +K + E V    WS      +  SGGC+N K TFL NPQY FD+  A+ +EV  CL Q+  R   R  G    + IG+ I +VE NR YR+H +   +   SS + N RS+FLR  LK GRY+ VP TF PG    F+ RI++    +  ELT   P           P++ T++ + +A  L  LD    ++P+ ++ CE +K  S +   T  P++D   +FYRK   K+PI + +Y+++ + D F+G+    G+  +  Q+   +L  K
Sbjct:    1 MFSSVKPFEGQEFSALRKQCQQNHTLFEDPVFRAEDQSLF--------LQGNRLGKVTWKRPKDLCEDPHLFVNGISAHDLNQGQLGNCWFVAACSSLASREALWQKVIPDWKDQEWDKNKPESYAGIFHFRFWRFGDWVDVVIDDRLPTANGKLIYCHSNDSNEFWSALVEKAYAKMCGCYEALDGGNTADALVDFTGGVSEPMDLLEGKFAQDEEARHQLFDRVLKVHNRGGLISCSIRATTQADMEARLDCGLVKGHAYAVTDVRKVRLGSGL--LAFFKSE----KLSMIRMRNPWGQREWNGAWSDSSEEWKRVSKGERERLGVTVEDDGEFWMDFDDFCKHFTDLILCRLINTSYLSIHKTWEEEVMRGCWSRHDDPLRNRSGGCINHKTTFLQNPQYVFDVTKAE-DEVLICLQQQDKRA--RAKGEN--MAIGFDIQRVELNRIYRMHSIQKSV--GSSIYINSRSVFLRKDLKEGRYVIVPSTFDPGMPGDFLLRIFTDVPSDCKELTVDEPPQTCWTSCCGYPKLVTQVHVIRADGLKALDGDGSSDPYIIISCEGEKVCSPVHKDTQSPDFDVKAVFYRKK-PKQPIRIQIYNKNLLSDSFMGQVTLNGDLSDLQQLHTLRLQDK 614          

Query:  159 MFDKPILYKNQNYTKIKSQLLETNTMFTDKEFPPNLTSLFSTLSNYDLTQNEELNNIRWRRP---------------------------GQICENPYLFVNGVSTNDVLQGRLGNCWFVAACTCITVYRENWMMLIPDYKSQEWTKEDKSEYCGIFKFRFWKYGQWTEVVIDDQLPTLENDLIYCHSNYRNEFWSALLEKAYAKILGSYEALEGGELIESLVDFTGGLAEPIVITDDHLKPDKSSK--LFQYLLKEHGNKSLIAAAIPAMTPEEQEEETSMGLIIGHAYAITMVIDLPVDTSKSDLKLVQSKVSNGHIRMMRLRNPWGQGEWKGPFCDGSPEWDVVSKSSRHRVGLTFQDDGEFWMTFIDFLNNFKSVVICHQINSIF---NKVYYESVFHSEW------SKGFSGGCLNFKNTFLDNPQYAFDINSADGEEVQFCLTQKMIRELNRNGGATGLLHIGYSILKVEANRQYRVHRLDHCLLEQSSAFKNGRSIFLRLHLKRGRYIAVPCTFQPGQIQSFMFRIYSKNSINTGELTQSLPSPGMSNYLVKVPEVATRISIFKAISLPRLDPIHGANPFFVLICENQKCISSICHGTMEPEWDESFIFYRKYFSKEPIVLLVYSRSGIIDEFIGKQAF--EGNGKEENQVLEFKLLGKKPDSVSHGSIFVQYKT 2081
            MF     ++ Q+Y+ +K Q L++  +F D  FP    SLF         Q   +  + W+RP                            ++C++P+LFV+G+S +D+ QG+LGNCWFVAAC+ +      W  +IPD+K QEW  E    Y GIF FRFW++G+W +VVIDD+LPT++N L+YCHSN  NEFWSAL+EKAYAK+ G YEAL+GG   ++LVDFTGG++EP+ + +     D++++  LF+ +LK H    LI+ +I A T E+ E     GL+ GHAYA+T V    V      L   +S+     + M+R+RNPWG+ EW GP+ D S EW  VSKS R ++G+T QDDGEFWM F DF + F  +++C  IN+ +   +K + E V    W       +  +GGC+N K TFL NPQY FD+   + +EV  CL QK  R   + G    L  IG+ I +VE NR+YR+H     +    S + N R +FLR  LK GRY+ +P TF PGQ   F+ R+++    +  ELT   P       +   P++ T++ +  A  L   D    ++P+ ++ CE +K  S +   T  P +D   IFYRK   +   + + +  + I+D F+G+     + N ++E   +  K  G + D+   G++ V+  T
Sbjct:    1 MFSSAKAFEGQHYSTLKRQCLQSGALFEDPLFPAVDDSLF--------YQGNRIGRVHWKRPEVSSIMPFSRSWNEARRRISFTDKHTSAELCDDPHLFVDGISAHDLHQGQLGNCWFVAACSSLASRESLWQKVIPDWKEQEWDPEKADSYAGIFHFRFWRFGEWVDVVIDDRLPTVDNQLVYCHSNDSNEFWSALVEKAYAKVYGCYEALDGGNTADALVDFTGGVSEPMDLLEGQFAQDETARNQLFERVLKVHNRDGLISCSIRATTVEDMEARLDCGLVKGHAYAVTDV--RKVRLGHGLLAYFKSE----KLHMIRMRNPWGEKEWSGPWSDSSEEWKKVSKSEREKLGVTVQDDGEFWMNFEDFCHYFTDLILCRLINTSYLSIHKTWEEEVMRGLWLHRDEPLRNRAGGCINHKTTFLQNPQYVFDVRKVE-DEVLICLQQKERRATPKEGKGENLA-IGFDIHRVELNRKYRMHSAQQKV--AGSIYINSRCVFLRKELKEGRYVIIPTTFDPGQQGEFLLRVFTDVPSDCKELTLDEPPQTCWTGMCGYPQLVTQVHVLSAEGLQGQDANGASDPYVIITCEGEKVRSPVHKDTRCPNFDIKGIFYRKKPKEGIHIEVSWKYNVIVDTFLGQVTLFSDPNDRQEQHTVYLKDKGSRQDNNLPGTLTVRVIT 663          

Query:  468 NWMMLIPDYKSQEWTKEDKSEYCGIFKFRFWKYGQWTEVVIDDQLPTLENDLIYCHSNYRNEFWSALLEKAYAKILGSYEALEGGELIESLVDFTGGLAEPIVITDDHLKPD--KSSKLFQYLLKEHGNKSLIAAAIPAMTPEEQEEETSMGLIIGHAYAITMVIDLPVDTSKSDLKLVQSKVSNGHIRMMRLRNPWGQGEWKGPFCDGSPEWDVVSKSSRHRVGLTFQDDGEFWMTFIDFLNNFKSVVICHQINSIF---NKVYYESVFHSEWS------KGFSGGCLNFKNTFLDNPQYAFDINSADGEEVQFCLTQKMIRELNRNGGATGLLHIGYSILKVEANRQYRVHRLDHCLLEQSSAFKNGRSIFLRLHLKRGRYIAVPCTFQPGQIQSFMFRIYSKNSINTGELTQSLPSPGMSNYLVKVPEVATRISIFKAISLPRLDPIHGANPFFVLICENQKCISSICHGTMEPEWDESFIFYRKYFSKEPIVLLVYSRSGIIDEFIGKQAFEG--NGKEENQVLEFKLLGKKPDSVSHGSI 2063
            +++++IPD+K QEW  +    Y GIF F FWK+G+W +VVIDD+LPT+ N LIYCHSN +NE W AL+EKAYAK+ G YEAL+GG   ++LVDFTGG++EPI +T+ H   D  K + LF+ +LK H    LI+ +I A +  + E   + GL+ GHAYA+T V    V      L   +S+     + M+R+RNPWG+ EW GP+ D S EW  VSKS R ++G+T +DDGEFWMTF DF   +  +++C  IN+ +   +K + E+V  S W       +  SGGCLNFK T+L NPQ+ FD+   + +EV  CL QK  R   + G A  L  IG+ I +VE NR++R+H L   +   SS + N R +FLR  LK GRY+ +P TF PG    F+ R+++    N  EL    P+    + L   P++ +++ +  A  L + D   GA+P+ ++ CE  K  S +    ++P+++   +FYRK    +PIV+ V++ + I DEF+G     G  N  +    LE +  G K      G+I
Sbjct:    9 SFIVVIPDWKEQEWYADKPQIYAGIFHFHFWKFGEWVDVVIDDRLPTINNQLIYCHSNEKNELWCALVEKAYAKLAGCYEALDGGNTADALVDFTGGVSEPIELTEGHFVTDVEKRNDLFERVLKVHNRGGLISCSIRATSASDMEARMACGLVKGHAYAVTDV--RKVRLGHGLLAFFKSE----KLEMIRMRNPWGEREWNGPWSDSSEEWQKVSKSEREKLGVTVEDDGEFWMTFEDFCKYYTDIIMCRLINTSYLSIHKTWEEAVLRSSWVQHQDPLQNRSGGCLNFKATYLQNPQFVFDVKKPE-DEVLVCLQQKTKRTTRQEGKAENLA-IGFEIHQVELNRRFRMHTLQPKV--ASSIYINSRCVFLRTDLKEGRYVIIPTTFDPGHTGEFLLRVFTDLPSNCCELKLDEPTKTCWSGLCGYPQLVSQVHVVSAQGLKQQDSNGGADPYVIISCEGNKVQSPVIKDCLDPKFNVKGVFYRKK-PGQPIVVQVWNHNVIKDEFMGLVDLSGDANNLQTQHSLELQDKGNKKSGTVSGTI 542          

Query:  183 KNQNYTKIKSQLLETNTMFTDKEFPPNLTSLFSTLSNYDLTQNEELNNIRWRRPGQICENPYLFVNGVSTNDVLQGRLGNCWFVAACTCITVYRENWMMLIPDYKSQEWTKEDKSEYCGIFKFRFWKYGQWTEVVIDDQLPTLENDLIYCHSNYRNEFWSALLEKAYAKILGSYEALEGGELIESLVDFTGGLAEPIVITDDHLKPD--KSSKLFQYLLKEHGNKSLIAAAIPAMTPEEQEEETSMGLIIGHAYAITMVIDLPVDTSKSDLKLVQSKVSNGHIRMMRLRNPWGQGEWKGPFCDGSPEWDVVSKSSRHRVGLTFQDDGEFWMTFIDFLNNFKSVVICHQINSIF---NKVYYESVFHSEWSKGF------SGGCLNFKNTFLDNPQYAFDINSADGEEVQFCLTQKMIRELNRNGGATGLLHIGYSILKVEANRQYRVHRLDHCLLEQSSAFKNGRSIFLRLHLKRGRYIAVPCTFQPGQIQSFMFRIYSKNSINTGELTQSLPSPGMSNYLVKVPEVATRISI 1748
            K QNY ++K + ++   +F D EFP +  SLF + +  DL        I W+RP ++CE+P+LFV+G+S++D+ QGRLGNCWFVAAC+C+ + +  W  +I ++K QEW  +    Y GIF F+FW  G W +VVIDD+LP+++ +L+YCHSN +NEFWSALLEKAYAK+ GSYEAL+GG   +++VDFTG + E   +     +    + +KLFQ LLK +    LI+  I  ++  + E  TS GL+ GHAY++T +  +PV       + +    ++  + M+R+RNPWG+ EWKG + D S EW+ VS+S +  +GLT  DDGEFWMTF D+  +F    +C  +N+ +    K + +   H  WSK        SGGC N + TF  NPQY F++   + +EV   L QK  R   ++G     + IG+ I KVE NR+YR+H++        S++ N R+IFLR  L  GRY+ +P TF PG   SF+ R+++  S    EL    P     + L   P+  T++ +
Sbjct:    9 KTQNYHELKKECIKNGKLFEDPEFPASDESLFYSKAP-DL-------RIEWKRPKELCEDPHLFVDGISSHDLHQGRLGNCWFVAACSCLALKKALWTKVISNWKKQEWDPKRPHRYAGIFHFKFWCLGDWVDVVIDDRLPSVDGNLVYCHSNVKNEFWSALLEKAYAKLAGSYEALDGGNTADAIVDFTGAVTESFELDKGDYRTSLMEQTKLFQELLKVYRAGGLISCYIKPVSSNDMEAVTSYGLVKGHAYSVTAIKKMPVG------QRILCFGNSNKLFMIRMRNPWGKREWKGAWSDESEEWNKVSRSEKATLGLTVADDGEFWMTFEDWCLSFTHADVCRILNTSYLSCYKTWKQEEVHGAWSKNTDPLLNRSGGCFN-ETTFFQNPQYIFEVRKKE-DEVLISLQQKDQRIHKKDGKGNNFI-IGFEIFKVELNREYRIHKISGQEKTLRSSYINLRAIFLRKVLTHGRYVIIPTTFHPGISSSFILRLFTDESSRFRELLLDKPKVSCWSLLCGYPQRVTQVLV 524          

Query:  474 MMLIPDYKSQEWTKEDKSEYCGIFKFRFWKYGQWTEVVIDDQLPTLENDLIYCHSNYRNEFWSALLEKAYAKILGSYEALEGGELIESLVDFTGGLAEPIVITDDHLKPD--KSSKLFQYLLKEHGNKSLIAAAIPAMTPEEQEEETSMGLIIGHAYAITMVIDLPVDTSKSDLKLVQSKVSNGHIRMMRLRNPWGQGEWKGPFCDGSPEWDVVSKSSRHRVGLTFQDDGEFWMTFIDFLNNFKSVVICHQINSIF---NKVYYESVFHSEWS------KGFSGGCLNFKNTFLDNPQYAFDINSADGEEVQFCLTQKMIRELNRNGGATGLLHIGYSILKVEANRQYRVHRLDHCLLEQSSAFKNGRSIFLRLHLKRGRYIAVPCTFQPGQIQSFMFRIYSKNSINTGELTQSLPSPGMSNYLVKVPEVATRISIFKAISLPRLDPIHGANPFFVLICENQKCISSICHGTMEPEWDESFIFYRKYFSKEPIVLLVYSRSGIIDEFIGKQAFEG--NGKEENQVLEFKLLGKKPDSVSHGSI 2063
            + +IPD+K QEW  +    Y GIF F FWK+G+W +VVIDD+LPT+ N LIYCHSN +NE W AL+EKAYAK+ G YEAL+GG   ++LVDFTGG++EPI +T+ H   D  K + LF+ +LK H    LI+ +I A +  + E   + GL+ GHAYA+T V    V      L   +S+     + M+R+RNPWG+ EW GP+ D S EW  VSKS R ++G+T +DDGEFWMTF DF   +  +++C  IN+ +   +K + E+V  S W       +  SGGCLNFK T+L NPQ+ FD+   + +EV  CL QK  R   + G A  L  IG+ I +VE NR++R+H L   +   SS + N R +FLR  LK GRY+ +P TF PG    F+ R+++    N  EL    P+    + L   P++ +++ +  A  L + D  +GA+P+ ++ CE  K  S +    ++P+++   +FYRK    +PIV+ V++ + I DEF+G     G  N  +    LE +  G K      G+I
Sbjct:   21 LQVIPDWKEQEWYADKPQIYAGIFHFHFWKFGEWVDVVIDDRLPTINNQLIYCHSNEKNELWCALVEKAYAKLAGCYEALDGGNTADALVDFTGGVSEPIELTEGHFVTDVEKRNDLFERVLKVHNRGGLISCSIRATSASDMEARMACGLVKGHAYAVTDV--RKVRLGHGLLAFFKSE----KLEMIRMRNPWGEREWNGPWSDSSEEWQKVSKSEREKLGVTVEDDGEFWMTFEDFCKYYTDIIMCRLINTSYLSIHKTWEEAVLRSSWVQHQDPLQNRSGGCLNFKATYLQNPQFVFDVKKPE-DEVLVCLQQKTKRTTRQEGKAENLA-IGFEIHQVELNRRFRMHTLQPKV--ASSIYINSRCVFLRTDLKEGRYVIIPTTFDPGHTGEFLLRVFTDLPSNCCELKLDEPTKTCWSGLCGYPQLVSQVHVVSAQGLKQQDS-NGADPYVIISCEGNKVQSPVIKDCLDPKFNVKGVFYRKK-PGQPIVVQVWNHNVIKDEFMGLVDLSGDANNLQTQHSLELQDKGNKKSGTVSGTI 551          

Query:  474 MMLIPDYKSQEWTKEDKSEYCGIFKFRFWKYGQWTEVVIDDQLPTLENDLIYCHSNYRNEFWSALLEKAYAKILGSYEALEGGELIESLVDFTGGLAEPIVITDDHLKPD--KSSKLFQYLLKEHGNKSLIAAAIPAMTPEEQEEETSMGLIIGHAYAITMVIDLPVDTSKSDLKLVQSKVSNGHIRMMRLRNPWGQGEWKGPFCDGSPEWDVVSKSSRHRVGLTFQDDGEFWMTFIDFLNNFKSVVICHQINSIF---NKVYYESVFHSEWS------KGFSGGCLNFKNTFLDNPQYAFDINSADGEEVQFCLTQKMIRELNRNGGATGLLHIGYSILKVEANRQYRVHRLDHCLLEQSSAFKNGRSIFLRLHLKRGRYIAVPCTFQPGQIQSFMFRIYSKNSINTGELTQSLPSPGMSNYLVKVPEVATRISIFKAISLPRLDPIHGANPFFVLICENQKCISSICHGTMEPEWDESFIFYRKYFSKEPIVLLVYSRSGIIDEFIGKQAFEG--NGKEENQVLEFKLLGKKPDSVSHGSI 2063
            + +IPD+K QEW  +    Y GIF F FWK+G+W +VVIDD+LPT+ N LIYCHSN +NE W AL+EKAYAK+ G YEAL+GG   ++LVDFTGG++EPI +T+ H   D  K + LF+ +LK H    LI+ +I A +  + E   + GL+ GHAYA+T V    V      L   +S+     + M+R+RNPWG+ EW GP+ D S EW  VSKS R ++G+T +DDGEFWMTF DF   +  +++C  IN+ +   +K + E+V  S W       +  SGGCLNFK T+L NPQ+ FD+   + +EV  CL QK  R   + G A  L  IG+ I +VE NR++R+H L   +   SS + N R +FLR  LK GRY+ +P TF PG    F+ R+++    N  EL    P+    + L   P++ +++ +  A  L + D  +GA+P+ ++ CE  K  S +    ++P+++   +FYRK    +PIV+ V++ + I DEF+G     G  N  +    LE +  G K      G+I
Sbjct:   36 LQVIPDWKEQEWYADKPQIYAGIFHFHFWKFGEWVDVVIDDRLPTINNQLIYCHSNEKNELWCALVEKAYAKLAGCYEALDGGNTADALVDFTGGVSEPIELTEGHFVTDVEKRNDLFERVLKVHNRGGLISCSIRATSASDMEARMACGLVKGHAYAVTDV--RKVRLGHGLLAFFKSE----KLEMIRMRNPWGEREWNGPWSDSSEEWQKVSKSEREKLGVTVEDDGEFWMTFEDFCKYYTDIIMCRLINTSYLSIHKTWEEAVLRSSWVQHQDPLQNRSGGCLNFKATYLQNPQFVFDVKKPE-DEVLVCLQQKTKRTTRQEGKAENLA-IGFEIHQVELNRRFRMHTLQPKV--ASSIYINSRCVFLRTDLKEGRYVIIPTTFDPGHTGEFLLRVFTDLPSNCCELKLDEPTKTCWSGLCGYPQLVSQVHVVSAQGLKQQDS-NGADPYVIISCEGNKVQSPVIKDCLDPKFNVKGVFYRKK-PGQPIVVQVWNHNVIKDEFMGLVDLSGDANNLQTQHSLELQDKGNKKSGTVSGTI 566          

Query:  474 MMLIPDYKSQEWTKEDKSEYCGIFKFRFWKYGQWTEVVIDDQLPTLENDLIYCHSNYRNEFWSALLEKAYAKILGSYEALEGGELIESLVDFTGGLAEPIVITDDHLKPD--KSSKLFQYLLKEHGNKSLIAAAIPAMTPEEQEEETSMGLIIGHAYAITMVIDLPVDTSKSDLKLVQSKVSNGHIRMMRLRNPWGQGEWKGPFCDGSPEWDVVSKSSRHRVGLTFQDDGEFWMTFIDFLNNFKSVVICHQINSIF---NKVYYESVFHSEWS------KGFSGGCLNFKNTFLDNPQYAFDINSADGEEVQFCLTQKMIRELNRNGGATGLLHIGYSILKVEANRQYRVHRLDHCLLEQSSAFKNGRSIFLRLHLKRGRYIAVPCTFQPGQIQSFMFRIYSKNSINTGELTQSLPSPGMSNYLVKVPEVATRISIFKAISLPRLDPIHGANPFFVLICENQKCISSICHGTMEPEWDESFIFYRKYFSKEPIVLLVYSRSGIIDEFIGKQAFEG--NGKEENQVLEFKLLGKKPDSVSHGSI 2063
            + +IPD+K QEW  +    Y GIF F FWK+G+W +VVIDD+LPT+ N LIYCHSN +NE W AL+EKAYAK+ G YEAL+GG   ++LVDFTGG++EPI +T+ H   D  K + LF+ +LK H    LI+ +I A +  + E   + GL+ GHAYA+T V    V      L   +S+     + M+R+RNPWG+ EW GP+ D S EW  VSKS R ++G+T +DDGEFWMTF DF   +  +++C  IN+ +   +K + E+V  S W       +  SGGCLNFK T+L NPQ+ FD+   + +EV  CL QK  R   + G A  L  IG+ I +VE NR++R+H L   +   SS + N R +FLR  LK GRY+ +P TF PG    F+ R+++    N  EL    P+    + L   P++ +++ +  A  L + D  +GA+P+ ++ CE  K  S +    ++P+++   +FYRK    +PIV+ V++ + I DEF+G     G  N  +    LE +  G K      G+I
Sbjct:   68 LQVIPDWKEQEWYADKPQIYAGIFHFHFWKFGEWVDVVIDDRLPTINNQLIYCHSNEKNELWCALVEKAYAKLAGCYEALDGGNTADALVDFTGGVSEPIELTEGHFVTDVEKRNDLFERVLKVHNRGGLISCSIRATSASDMEARMACGLVKGHAYAVTDV--RKVRLGHGLLAFFKSE----KLEMIRMRNPWGEREWNGPWSDSSEEWQKVSKSEREKLGVTVEDDGEFWMTFEDFCKYYTDIIMCRLINTSYLSIHKTWEEAVLRSSWVQHQDPLQNRSGGCLNFKATYLQNPQFVFDVKKPE-DEVLVCLQQKTKRTTRQEGKAENLA-IGFEIHQVELNRRFRMHTLQPKV--ASSIYINSRCVFLRTDLKEGRYVIIPTTFDPGHTGEFLLRVFTDLPSNCCELKLDEPTKTCWSGLCGYPQLVSQVHVVSAQGLKQQDS-NGADPYVIISCEGNKVQSPVIKDCLDPKFNVKGVFYRKK-PGQPIVVQVWNHNVIKDEFMGLVDLSGDANNLQTQHSLELQDKGNKKSGTVSGTI 598          

Query:  159 MFDKPILYKNQNYTKIKSQLLETNTMFTDKEFPPNLTSLFSTLSNYDLTQNEELNNIRWRRPGQICENPYLFVNGVSTNDVLQGRLGNCWFVAACTCITVYRENWMMLIPDYKSQEWTKEDKSEYCGIFKFRFWKYGQWTEVVIDDQLPTLENDLIYCHSNYRNEFWSALLEKAYAKILGSYEALEGGELIESLVDFTGGLAEPIVITDDHLKPD--KSSKLFQYLLKEHGNKSLIAAAIPAMTPEEQEEETSMGLIIGHAYAITMVIDLPVDTSKSDLKLVQSKVSNGHIRMMRLRNPWGQGEWKGPFCDGSPEWDVVSKSSRHRVGLTFQDDGEFWMTFIDFLNNFKSVVICHQINSIF---NKVYYESVFHSEWSK------GFSGGCLNFKNTFLDNPQYAFDINSADGEEVQFCLTQKMIRELNRNGGATGLLHIGYSILKVEANRQYRVHRLDHCLLEQSSAFKNGRSIFLRLHLKRGRYIAVPCTFQPGQIQSFMFRIYSKNSINTGELTQSLPSPGMSNYLVKVPEVATRISIFKAISLPRLDPIHGANPFFVLICENQKCISSICHGTMEPEWDESFIFYRKYFSKEPIVLLVYSRSGIIDEFIGK 1970
            MF     Y++QNY+ +K   L    +F D  FP    SL+     Y  T       +RW+RP  IC++P LFV+G+S++D+ QG++GNCWFVAAC+ +      W  +IPD+K QEW  E    Y GIF F FW++G+W +V++DD+LPT+ N LIYCHSN +NEFW AL+EKAYAK+ G Y+AL+GG   ++LVDFTGG++EPI +T+  L  D  K ++LF+ +LK H    LI+A+I A+T  + E   + GL+ GHAYA+T V    V      L   +S+     + M+RLRNPWG+ EW GP+ D S EW  VSKS R ++G+T QDDGEFWMTF D    F  ++ C  IN+ +   +K + E+  H  W++        SGGC+N K+TF  NPQY F++   + +EV   + Q+  R   R G    L  IG+ I KVE NRQYR+H L H     SS + N RS+FLR  L  GRY+ +P TF+PG    F+ R+++    N  EL    P     + L   P+   ++ +  A  L   D   GAN + ++ CE +K  S++  GT  PE++   IFYRK  + +PI + V++   + DEF+G+
Sbjct:    1 MFSCAKAYEDQNYSALKRACLRKKVLFEDPLFPATDDSLY-----YKGTPGP---TVRWKRPKDICDDPRLFVDGISSHDLHQGQVGNCWFVAACSSLASRESLWQKVIPDWKEQEWNPEKPDSYAGIFHFNFWRFGEWVDVIVDDRLPTVNNQLIYCHSNSKNEFWCALVEKAYAKLAGCYQALDGGNTADALVDFTGGVSEPIDLTEGDLATDEAKRNQLFERVLKVHSRGGLISASIKAVTAADMEARLACGLVKGHAYAVTDV--RKVRLGHGLLAFFKSE----KLDMIRLRNPWGEREWTGPWSDTSEEWQKVSKSEREKMGVTVQDDGEFWMTFEDMCRYFTDIIKCRLINTSYLSIHKTWEEARLHGAWTRHEDPQQNRSGGCINHKDTFFQNPQYVFEVKKPE-DEVLISIQQRPKRSTRREGKGENLA-IGFDIYKVEENRQYRMHSLQH--KAASSIYINSRSVFLRTELPEGRYVIIPTTFEPGHTGEFLLRVFTDVPSNCRELRLDEPPRTCWSSLCGYPQQVAQVHVLGAAGLK--DSPTGANSYVIIKCEGEKVRSAVQRGTSTPEYNVKGIFYRKKLA-QPITVQVWNHRVLKDEFLGQ 594          

Query:  159 MFDKPILYKNQNYTKIKSQLLETNTMFTDKEFPPNLTSLFSTLSNYDLTQNEELNNIRWRRPGQICENPYLFVNGVSTNDVLQGRLGNCWFVAACTCITVYRENWMMLIPDYKSQEWTKEDKSEYCGIFKFRFWKYGQWTEVVIDDQLPTLENDLIYCHSNYRNEFWSALLEKAYAKILGSYEALEGGELIESLVDFTGGLAEPIVITDDHLKPD--KSSKLFQYLLKEHGNKSLIAAAIPAMTPEEQEEETSMGLIIGHAYAITMVIDLPVDTSKSDLKLVQSKVSNGHIRMMRLRNPWGQGEWKGPFCDGSPEWDVVSKSSRHRVGLTFQDDGEFWMTFIDFLNNFKSVVICHQINSIF---NKVYYESVFHSEWSK------GFSGGCLNFKNTFLDNPQYAFDINSADGEEVQFCLTQKMIRELNRNGGATGLLHIGYSILKVEANRQYRVHRLDHCLLEQSSAFKNGRSIFLRLHLKRGRYIAVPCTFQPGQIQSFMFRIYSKNSINTGELTQSLPSPGMSNYLVKVPEVATRISIFKAISLPRLDPIHGANPFFVLICENQKCISSICHGTMEPEWDESFIFYRKYFSKEPIVLLVYSRSGIIDEFIGK 1970
            MF     Y++QNY+ +K   L    +F D  FP    SL+     Y  T       +RW+RP  IC++P LFV+G+S++D+ QG++GNCWFVAAC+ +      W  +IPD+K QEW  E    Y GIF F FW++G+W +V++DD+LPT+ N LIYCHSN +NEFW AL+EKAYAK+ G Y+AL+GG   ++LVDFTGG++EPI +T+  L  D  K ++LF+ +LK H    LI+A+I A+T  + E   + GL+ GHAYA+T V    V      L   +S+     + M+RLRNPWG+ EW GP+ D S EW  VSKS R ++G+T QDDGEFWMTF D    F  ++ C  IN+ +   +K + E+  H  W++        SGGC+N K+TF  NPQY F++   + +EV   + Q+  R   R G    L  IG+ I KVE NRQYR+H L H     SS + N RS+FLR  L  GRY+ +P TF+PG    F+ R+++    N  EL    P     + L   P+   ++ +  A  L   D   GAN + ++ CE +K  S++  GT  PE++   IFYRK  + +PI + V++   + DEF+G+
Sbjct:    1 MFSCAKAYEDQNYSALKRACLRKKVLFEDPLFPATDDSLY-----YKGTPGP---TVRWKRPKDICDDPRLFVDGISSHDLHQGQVGNCWFVAACSSLASRESLWQKVIPDWKEQEWNPEKPDSYAGIFHFNFWRFGEWVDVIVDDRLPTVNNQLIYCHSNSKNEFWCALVEKAYAKLAGCYQALDGGNTADALVDFTGGVSEPIDLTEGDLATDEAKRNQLFERVLKVHSRGGLISASIKAVTAADMEARLACGLVKGHAYAVTDV--RKVRLGHGLLAFFKSE----KLDMIRLRNPWGEREWTGPWSDTSEEWQKVSKSEREKMGVTVQDDGEFWMTFEDMCRYFTDIIKCRLINTSYLSIHKTWEEARLHGAWTRHEDPQQNRSGGCINHKDTFFQNPQYVFEVKKPE-DEVLISIQQRPKRSTRREGKGENLA-IGFDIYKVEENRQYRMHSLQH--KAASSIYINSRSVFLRTELPEGRYVIIPTTFEPGHTGEFLLRVFTDVPSNCRELRLDEPPRTCWSSLCGYPQQVAQVHVLGAAGLK--DSPTGANSYVIIKCEGEKVRSAVQRGTSTPEYNVKGIFYRKKLA-QPITVQVWNHRVLKDEFLGQ 594          

Query:  177 LYKNQNYTKIKSQLLETNTMFTDKEFPPNLTSLFSTLSNYDLTQNEEL-NNIRWRRPGQICENPYLFVNGVSTNDVLQGRLGNCWFVAACTCITVYRENWMMLIPDYKSQEWTKEDKSEYCGIFKFRFWKYGQWTEVVIDDQLPTLENDLIYCHSNYRNEFWSALLEKAYAKILGSYEALEGGELIESLVDFTGGLAEPIVITDDHLKP--DKSSKLFQYLLKEHGNKSLIAAAIPAMTPEEQEEETSMGLIIGHAYAITMVIDLPVDTSKSDLKLVQSKVSNGHIRMMRLRNPWGQGEWKGPFCDGSPEWDVVSKSSRHRVGLTFQDDGEFWMTFIDFLNNFKSVVICHQINS-IFNKVYYESVFHSEWS------KGFSGGCLNFKNTFLDNPQYAFDINSADGEEVQFCLTQKMIRELNRNGGATGLLHIGYSILKVEANRQYRVHRLDHCLLEQSSAFKNGRSIFLRLHLKRGRYIAVPCTFQPGQIQSFMFRIYSKNSINTGELTQSLPSPGMSNYLVKVPEVATRISIFKAISLPRLDPIHGANPFFVLICENQKCISSICHGTMEPEWDESFIFYRKYFSKEPIVLLVYSRSGIIDEFIGKQAFEGN 1988
            L+KNQ Y ++K + ++   +F D  F P   SLF          N  L   + W+RP  I ++P+L V  +S + ++QGRLGN   ++A +C+ V   +W   IP++K QEW      +Y GIF FRFW +G+WTEVVIDD LPT+  DL++  S   NEFW+ALLEKAYAK+LG YEAL+G  + + ++DFTG LAE I +         ++  KLF  L K      LI  +I + + EEQE ET  GL+ G+ Y +T +  L +       +LV+   S   + M+RLRNP G+ EW GP+ + S EW  ++ + R  +GL   DDGEFWM+  DF +NF  + +C  +N+ +F +   ESV    W+         SGGC N ++TFL NPQY F +   DG +V   L QK +R   R G     + IG+ + KVE NR++R+H L       +S + + R++FL  +LK+G Y+ VP  FQ G+   F+ RI+S+  +   ELT  +P     N     P+V T+I++  A  L +       NP+ ++ C  ++  S +   T+   +D   IFYR+  +  PI++ V++     D+F+G+   + +
Sbjct:    7 LFKNQKYQELKQECMKDGRLFCDPTFLPENDSLFF---------NRLLPGKVVWKRPQDISDDPHLIVGNISNHQLIQGRLGNKAMISAFSCLAVQESHWTKAIPNHKDQEWDPRKPEKYAGIFHFRFWHFGEWTEVVIDDLLPTINGDLVFSFSTSMNEFWNALLEKAYAKLLGCYEALDGLTITDIIMDFTGTLAEIIDMQKGRYTDLVEEKYKLFGELYKTFTKGGLICCSIESPSQEEQEVETDWGLLKGYTYTMTDIRKLRLGE-----RLVEV-FSTEKLYMVRLRNPLGRQEWSGPWSEISEEWQQLTVTDRKNLGLVMSDDGEFWMSLEDFCHNFHKLNVCRNVNNPVFGRKELESVVGC-WTVDDDPLMNRSGGCYNNRDTFLQNPQYIFTV-PEDGHKVIMSLQQKDLRTYRRMGRPDNYI-IGFELFKVEMNRRFRLHHLYIQERAGTSTYIDTRTVFLSKYLKKGSYVLVPTMFQHGRTSEFLLRIFSEVPVQLRELTLDMPKMSCWNLARGYPKVVTQITVHSAEGLEKKYANETVNPYLIIKCGKEEVRSPVQKNTVHAIFDTQAIFYRRT-TDIPIIIQVWNSRKFCDQFLGQVTLDAD 601          

Query:  156 GMFDKPILYKNQNYTKIKSQLLETNTMFTDKEFPPNLTSLFSTLSNYDLTQNEELNNIRWRRPGQICENPYLFVNGVSTNDVLQGRLGNCWFVAACTCITVYRENWMMLIPDYKSQEWTKEDKSEYCGIFKFRFWKYGQWTEVVIDDQLPTLENDLIYCHSNYRNEFWSALLEKAYAKILGSYEALEGGELIESLVDFTGGLAEPIVITDDHLKPDKSSKLFQYLLKEHGNKSLIAAAIPAMTPEEQEEETSMGLIIGHAYAITMVIDLPVDTSKSDLKLVQSKVSNGHIRMMRLRNPWGQGEWKGPFCDGSPEWDVVSKSSRHRVGLTFQDDGEFWMTFIDFLNNFKSVVICH----QINSIFNKVYYESVFHSEWSKGFS-GGCLNFKNTFLDNPQYAFDINSADGEEVQ--------FCLTQKMIRELNRNGGATGLLHIGYSILKV----EANRQY--RVHRLDHCLLEQSSAFKNGRSIFLRLHLKRGRYIAVPCTFQPGQIQSFMFRIYSKN------SINTGELTQSLPSPGMSN 1706
            G   +P+ ++ Q++  +K Q L    +F D+ FP  + +L S    ++L+Q  ++  I W+RP +ICENP   + G +  D+ QG LG+CWF+AA  C+T+       +IP    Q +T+     Y GIF F+FW+YG W +VVIDD LPT  N L++  SN+RNEFWSALLEKAYAK+ GSYEAL+GG   E++ DFTGG+ E   I       D  S +++ + K     SL+  +I  + P + E   + GL+ GHAY++T               L ++      ++++RLRNPWGQ EW G + DG  +W  V K  + R+     +DGEFWM++ DF+ +F  + IC+     + S   + +  SV    W +G S GGC NF +TF  NPQY   +   D +             L QK  R+ +R  GA  L  IG++I +V      N+Q+  +   L +    +S  + N R +  R  L    Y+ VP T++P Q   F+ R++S+       + NT  + + +P PG ++
Sbjct:   24 GTVSQPLKFEGQDFVVLKQQCLAQKCLFEDRVFPAGVQALGS----HELSQKAKMKAITWKRPKEICENPRFIIGGANRTDICQGDLGDCWFLAAIACLTLNERLLFRVIP--HDQSFTEN----YAGIFHFQFWRYGDWVDVVIDDCLPTYNNQLVFTKSNHRNEFWSALLEKAYAKLHGSYEALKGGNTTEAMEDFTGGVTEFFEI------KDAPSDMYKIMRKAIERGSLMGCSIDTIVPVQYETRMACGLVKGHAYSVT--------------GLEEALFKGEKVKLVRLRNPWGQVEWNGSWSDGWKDWSFVDKDEKARLQHQVTEDGEFWMSYDDFVYHFTKLEICNLTADALESDKLQTWTVSVNEGRWVRGCSAGGCRNFPDTFWTNPQYRLKLLEEDDDPEDSEVICSFLVALMQKNRRK-DRKLGAN-LFTIGFAIYEVPKEMHGNKQHLQKDFFLYNASKARSKTYINMREVSQRFRLPPSEYVIVPSTYEPHQEGEFILRVFSEKRNLSEEAENTISVDRPVPRPGHTD 533          

Query:  156 GMFDKPILYKNQNYTKIKSQLLETNTMFTDKEFPPNLTSLFSTLSNYDLTQNEELNNIRWRRPGQICENPYLFVNGVSTNDVLQGRLGNCWFVAACTCITVYRENWMMLIPDYKSQEWTKEDKSEYCGIFKFRFWKYGQWTEVVIDDQLPTLENDLIYCHSNYRNEFWSALLEKAYAKILGSYEALEGGELIESLVDFTGGLAEPIVITDDHLKPDKSSKLFQYLLKEHGNKSLIAAAIPAMTPEEQEEETSMGLIIGHAYAITMVIDLPVDTSKSDLKLVQSKVSNGHIRMMRLRNPWGQGEWKGPFCDGSPEWDVVSKSSRHRVGLTFQDDGEFWMTFIDFLNNFKSVVICH----QINSIFNKVYYESVFHSEWSKGFS-GGCLNFKNTFLDNPQYAFDINSADGEEVQ--------FCLTQKMIRELNRNGGATGLLHIGYSILKV----EANRQY--RVHRLDHCLLEQSSAFKNGRSIFLRLHLKRGRYIAVPCTFQPGQIQSFMFRIYSKN------SINTGELTQSLPSPGMSN 1706
            G   +P+ ++ Q++  +K Q L    +F D+ FP  + +L S    ++L+Q  ++  I W+RP +ICENP   + G +  D+ QG LG+CWF+AA  C+T+       +IP    Q +T+     Y GIF F+FW+YG W +VVIDD LPT  N L++  SN+RNEFWSALLEKAYAK+ GSYEAL+GG   E++ DFTGG+ E   I       D  S +++ + K     SL+  +I  + P + E   + GL+ GHAY++T               L ++      ++++RLRNPWGQ EW G + DG  +W  V K  + R+     +DGEFWM++ DF+ +F  + IC+     + S   + +  SV    W +G S GGC NF +TF  NPQY   +   D +             L QK  R+ +R  GA  L  IG++I +V      N+Q+  +   L +    +S  + N R +  R  L    Y+ VP T++P Q   F+ R++S+       + NT  + + +P PG ++
Sbjct:   24 GTVSQPLKFEGQDFVVLKQQCLAQKCLFEDRVFPAGVQALGS----HELSQKAKMKAITWKRPKEICENPRFIIGGANRTDICQGDLGDCWFLAAIACLTLNERLLFRVIP--HDQSFTEN----YAGIFHFQFWRYGDWVDVVIDDCLPTYNNQLVFTKSNHRNEFWSALLEKAYAKLHGSYEALKGGNTTEAMEDFTGGVTEFFEIK------DAPSDMYKIMRKAIERGSLMGCSIDTIVPVQYETRMACGLVKGHAYSVT--------------GLEEALFKGEKVKLVRLRNPWGQVEWNGSWSDGWKDWSFVDKDEKARLQHQVTEDGEFWMSYDDFVYHFTKLEICNLTADALESDKLQTWTVSVNEGRWVRGCSAGGCRNFPDTFWTNPQYRLKLLEEDDDPEDSEVICSFLVALMQKNRRK-DRKLGAN-LFTIGFAIYEVPKEMHGNKQHLQKDFFLYNASKARSKTYINMREVSQRFRLPPSEYVIVPSTYEPHQEGEFILRVFSEKRNLSEEAENTISVDRPVPRPGHTD 533          

Query:  159 MFDKPILYKNQNYTKIKSQLLETNTMFTDKEFPPNLTSLFSTLSNYDLTQNEELNNIRWRRPGQICENPYLFVNGVSTNDVLQGRLGNCWFVAACTCITVYRENWMMLIPDYKSQEWTKEDKSEYCGIFKFRFWKYGQWTEVVIDDQLPTLENDLIYCHSNYRNEFWSALLEKAYAKILGSYEALEGGELIESLVDFTGGLAEPIVITDDHLKPD--KSSKLFQYLLKEHGNKSLIAAAIPAMTPEEQEEETSMGLIIGHAYAITMVIDLPVDTSKSDLKLVQSKVSNGHIRMMRLRNPWGQGEWKGPFCDGSPEWDVVSKSSRHRVGLTFQDDGEFWMTFIDFLNNFKSVVICHQINSIF---NKVYYESVFHSEWSK------GFSGGCLNFKNTFLDNPQYAFDINSADGEEVQFCLTQKMIRELNRNGGATGLLHIGYSILKVEANRQYRVHRLDHCLLEQSSAFKNGRSIFLRLHLKRGRYIAVPCTFQPGQIQSFMFRIYSKNSINTGELTQSLPSPGMSNYLVKVPEVATRISIFKAISLPRLDPIHGANPFFVLICENQKCISSICHGTMEPEWDESFIFYRKYFSKEPIVLLVYSRSGIIDEFIGK 1970
            MF     Y++QNY+ +K   L    +F D  FP    SL+     Y  T       +RW+RP  IC++P LFV+G+S++D+ QG++GNCWFVAAC+ +      W  +IPD+K QEW  E    Y GIF F FW++G+W +V++DD+LPT+ N LIYCHSN +NEFW AL+EKAYAK+ G Y+AL+GG   ++LVDFTGG++EPI +T+  L  D  K ++LF+ +LK H    LI+A+I A+T  + E   + GL+ GHAYA+T V    V      L   +S+     + M+RLRNPWG+ EW GP+ D S EW  VSKS R ++G+T QDDGEFWMTF D    F  ++ C  IN+ +   +K + E+  H  W++        SGGC+N K+TF  NPQY F++   + +EV   + Q+  R   R G    L  IG+ I KVE NRQYR+H L H     SS + N RS+FLR  L  GRY+ +P TF+PG    F+ R+++    N  EL    P     + L   P+   ++ +  A  L   D   GAN + ++ CE +K  S++  GT  PE++   IFYRK  + +PI + V++   + DEF+G+
Sbjct:    1 MFSCAKAYEDQNYSALKRACLRKKVLFEDPLFPATDDSLY-----YKGTPGP---TVRWKRPKDICDDPRLFVDGISSHDLHQGQVGNCWFVAACSSLASRESLWQKVIPDWKEQEWNPEKPDSYAGIFHFNFWRFGEWVDVIVDDRLPTVNNQLIYCHSNSKNEFWCALVEKAYAKLAGCYQALDGGNTADALVDFTGGVSEPIDLTEGDLATDEAKRNQLFERVLKVHSRGGLISASIKAVTAADMEARLACGLVKGHAYAVTDV--RKVRLGHGLLAFFKSE----KLDMIRLRNPWGEREWTGPWSDTSEEWQKVSKSEREKMGVTVQDDGEFWMTFEDMCRYFTDIIKCRLINTSYLSIHKTWEEARLHGAWTRHEDPQQNRSGGCINHKDTFFQNPQYVFEVKKPE-DEVLISIQQRPKRSTRREGKGENLA-IGFDIYKVEENRQYRMHSLQH--KAASSIYINSRSVFLRTELPEGRYVIIPTTFEPGHTGEFLLRVFTDVPSNCRELRLDEPPRTCWSSLCGYPQQVAQVHVLGAAGLK--DSPTGANSYVIIKCEGEKVRSAVQRGTSTPEYNVKGIFYRKKLA-QPITVQVWNHRVLKDEFLGQ 594          

Query:  159 MFDKPILYKNQNYTKIKSQLLETNTMFTDKEFPPNLTSLFSTLSNYDLTQNEELNNIRWRRPGQICENPYLFVNGVSTNDVLQGRLGNCWFVAACTCITVYRENWMMLIPDYKSQEWTKEDKSEYCGIFKFRFWKYGQWTEVVIDDQLPTLENDLIYCHSNYRNEFWSALLEKAYAKILGSYEALEGGELIESLVDFTGGLAEPIVITDDHLKPD--KSSKLFQYLLKEHGNKSLIAAAIPAMTPEEQEEETSMGLIIGHAYAITMVIDLPVDTSKSDLKLVQSKVSNGHIRMMRLRNPWGQGEWKGPFCDGSPEWDVVSKSSRHRVGLTFQDDGEFWMTFIDFLNNFKSVVICHQINSIF---NKVYYESVFHSEWSK------GFSGGCLNFKNTFLDNPQYAFDINSADGEEVQFCLTQKMIRELNRNGGATGLLHIGYSILKVEANRQYRVHRLDHCLLEQSSAFKNGRSIFLRLHLKRGRYIAVPCTFQPGQIQSFMFRIYSKNSINTGELTQSLPSPGMSNYLVKVPEVATRISIFKAISLPRLDPIHGANPFFVLICENQKCISSICHGTMEPEWDESFIFYRKYFSKEPIVLLVYSRSGIIDEFIGK 1970
            MF     Y+ QNY+ +K   L    +F D  FP +  SL+     Y  T       +RW+RP  IC++P LFV+G+S++D+ QG++GNCWFVAAC+ +      W  +IPD+K QEW  E    Y GIF F FW++G+W +VV+DD+LPT+ N LIYCHSN +NEFW A +EKAYAK+ G Y+AL+GG   ++LVDFTGG++EPI +T+  L  D  K S+LF+ +LK H    LI+A+I AMT  + E   + GL+ GHAYA+T V    V      L   +S+     + M+RLRNPWG+  W GP+ D S EW  VSKS R ++G+T QDDGEFWMT+ D    F  ++ C  IN+ +   +K + E+     W++        SGGC+N K+TF  NPQY F++   + +EV  C+ Q+  R   R G    L  IG+ I KVE NRQYR+H L H     SS + N RS+FLR  L  GRY+ +P TF+PG     + R+++    N  EL    P     + L   P+  T++ +  A  L   D   GAN + ++ CE +K  S++  GT  PE++   IFYRK  S +PI + V++   + DEF+G+
Sbjct:    1 MFSCTKAYEYQNYSALKRACLRRKVLFEDPHFPASDDSLY-----YKGTPGP---TVRWKRPFDICDDPRLFVDGISSHDLHQGQVGNCWFVAACSSLASRESLWQKVIPDWKEQEWNPEKPDSYAGIFHFNFWRFGEWVDVVVDDRLPTVNNQLIYCHSNSKNEFWCAPVEKAYAKLAGCYQALDGGNTADALVDFTGGVSEPIDLTEGDLATDEAKRSQLFERVLKVHSRGGLISASIKAMTAADMETRLACGLVKGHAYAVTDV--RKVRLGHGLLAFFKSE----KLDMIRLRNPWGERVWTGPWSDTSEEWQKVSKSEREKMGVTVQDDGEFWMTYEDMCRYFTDIIKCRLINTSYLSIHKTWEEARLRGAWTRHEDPQQNRSGGCINHKDTFFQNPQYIFEVKKPE-DEVLICIQQRPKRSTRREGKGENLA-IGFDIYKVEENRQYRMHSLQH--KAASSIYINSRSVFLRTELPEGRYVIIPTTFEPGHTGELLLRVFTDVPSNCRELRLDEPPRTCWSSLCGYPQQVTQVHVLGAAGLK--DSSTGANSYVIIKCEGEKVRSAVQRGTSTPEYNVKGIFYRKKLS-QPITVQVWNNRVLKDEFLGQ 594          

Query:  159 MFDKPILYKNQNYTKIKSQLLETNTMFTDKEFPPNLTSLFSTLSNYDLTQNEELNNIRWRRPGQICENPYLFVNGVSTNDVLQGRLGNCWFVAACTCITVYRENWMMLIPDYKSQEWTKEDKSEYCGIFKFRFWKYGQWTEVVIDDQLPTLENDLIYCHSNYRNEFWSALLEKAYAKILGSYEALEGGELIESLVDFTGGLAEPIVITDDHLKPD--KSSKLFQYLLKEHGNKSLIAAAIPAMTPEEQEEETSMGLIIGHAYAITMVIDLPVDTSKSDLKLVQSKVSNGHIRMMRLRNPWGQGEWKGPFCDGSPEWDVVSKSSRHRVGLTFQDDGEFWMTFIDFLNNFKSVVICHQINS---IFNKVYYESVFHSEWS------KGFSGGCLNFKNTFLDNPQYAFDINSADGEEVQFCLTQKMIRELNRNGGATGLLHIGYSILKVEANRQYRVHRLDHCLLEQSSAFKNGRSIFLRLHLKRGRYIAVPCTFQPGQIQSFMFRIYSKNSINTGELTQSLPSPGMSNYLVKVPEVATRISIFKAISLPRLDPIHGANPFFVLICENQKCISSICHGTMEPEWDESFIFYRKYFSKEPIVLLVYSRSGIIDEFIGK 1970
            MF     Y++QNY+ ++        +F D  FP    SL+     Y  T       +RW+RP  ICE+P LFV+G+S++D+ QG++GNCWFVAAC+ +      W  +IPD+K QEW  E  + Y GIF F FW++G+W +VVIDD+LPT+ N LIYCHSN RNEFW AL+EKAYAK+ G Y+AL+GG   ++LVDFTGG++EPI +T+     D  K ++LF+ +LK H    LI+A+I A+T  + E   + GL+ GHAYA+T V    V      L   +S+     + M+RLRNPWG+ EW GP+ D S EW  VSKS R ++G+T QDDGEFWMTF D    F  ++ C  IN+     +K + E+  H  W+      +   GGC+N K+TF  NPQY F++   + +EV  C+ Q+  R   R G    L  IG+ I KVE NRQYR+H L H     SS + N RS+FLR     GRY+ +P TF+PG    F+ R+++    N  EL    P     + L   P++ T++ +  A  L   D   GAN + ++ CE  K  S++  GT  PE++   IFYRK  S +PI + V++   + DEF+G+
Sbjct:    1 MFSCVKPYEDQNYSALRRDCRRRKVLFEDPLFPATDDSLY-----YKGTPGPA---VRWKRPKGICEDPRLFVDGISSHDLHQGQVGNCWFVAACSSLASRESLWQKVIPDWKEQEWDPEKPNAYAGIFHFHFWRFGEWVDVVIDDRLPTVNNQLIYCHSNSRNEFWCALVEKAYAKLAGCYQALDGGNTADALVDFTGGVSEPIDLTEGDFANDETKRNQLFERMLKVHSRGGLISASIKAVTAADMEARLACGLVKGHAYAVTDV--RKVRLGHGLLAFFKSE----KLDMIRLRNPWGEREWNGPWSDTSEEWQKVSKSEREKMGVTVQDDGEFWMTFEDVCRYFTDIIKCRVINTSHLSIHKTWEEARLHGAWTLHEDPRQNRGGGCINHKDTFFQNPQYIFEVKKPE-DEVLICIQQRPKRSTRREGKGENLA-IGFDIYKVEENRQYRMHSLQH--KAASSIYINSRSVFLRTDQPEGRYVIIPTTFEPGHTGEFLLRVFTDVPSNCRELRLDEPPHTCWSSLCGYPQLVTQVHVLGAAGLK--DSPTGANSYVIIKCEGDKVRSAVQKGTSTPEYNVKGIFYRKKLS-QPITVQVWNHRVLKDEFLGQ 594          

Query:  177 LYKNQNYTKIKSQLLETNTMFTDKEFPPNLTSLFSTLSNYDLTQNEEL-NNIRWRRPGQICENPYLFVNGVSTNDVLQGRLGNCWFVAACTCITVYRENWMMLIPDYKSQEWTKEDKSEYCGIFKFRFWKYGQWTEVVIDDQLPTLENDLIYCHSNYRNEFWSALLEKAYAKILGSYEALEGGELIESLVDFTGGLAEPIVITDDHLKP--DKSSKLFQYLLKEHGNKSLIAAAIPAMTPEEQEEETSMGLIIGHAYAITMVIDLPVDTSKSDLKLVQSKVSNGHIRMMRLRNPWGQGEWKGPFCDGSPEWDVVSKSSRHRVGLTFQDDGEFWMTFIDFLNNFKSVVICHQINS-IFNKVYYESVFHSEWS------KGFSGGCLNFKNTFLDNPQYAFDINSADGEEVQFCLTQKMIRELNRNGGATGLLHIGYSILKVEANRQYRVHRLDHCLLEQSSAFKNGRSIFLRLHLKRGRYIAVPCTFQPGQIQSFMFRIYSKNSINTGELTQSLPSPGMSNYLVKVPEVATRISIFKAISLPRLDPIHGANPFFVLICENQKCISSICHGTMEPEWDESFIFYRKYFSKEPIVLLVYSRSGIIDEFIGKQAFEGN 1988
            L+KNQ Y ++K + ++ + +F D  F P   SLF          N  L   + W+RP  IC++P+L V  +S + + QGRLG+   V+A +C+ V   +W   IP++K QEW  +   +Y GIF FRFW +G+WTEVVIDD LPT+  DL++  S   NEFW+ALLEKAYAK+LG YEAL+G  + + +VDFTG LAE + +         ++  KLF  L K      LI  +I +   EEQE ET  GL+ GH Y +T +  + +       +LV+   S   + M+RLRNP G+ EW GP+ + S EW  ++ S R  +GL   DDGEFWM+  DF  NF  + +C  +N+ IF +   ESV    W+         SGGC N ++TFL NPQY F +   DG +V   L QK +R   R G     + IG+ + KVE NR++R+H L       +S + + R++FL  +LK+G Y+ VP  FQ G+   F+ RI+S+  +   ELT  +P     N     P+V T+I++  A  L +       NP+ V+ C  ++  S +   T+   +D   IFYR+  +  PI++ V++     D+F+G+   + +
Sbjct:    7 LFKNQKYQELKQECIKDSRLFCDPTFLPENDSLFY---------NRLLPGKVVWKRPQDICDDPHLIVGNISNHQLTQGRLGHKPMVSAFSCLAVQESHWTKTIPNHKEQEWDPQKTEKYAGIFHFRFWHFGEWTEVVIDDLLPTINGDLVFSFSTSMNEFWNALLEKAYAKLLGCYEALDGLTITDIIVDFTGTLAETVDMQKGRYTELVEEKYKLFGELYKTFTKGGLICCSIESPNQEEQEVETDWGLLKGHTYTMTDIRKIRLGE-----RLVEV-FSAEKVYMVRLRNPLGRQEWSGPWSEISEEWQQLTASDRKNLGLVMSDDGEFWMSLEDFCRNFHKLNVCRNVNNPIFGRKELESVLGC-WTVDDDPLMNRSGGCYNNRDTFLQNPQYIFTV-PEDGHKVIMSLQQKDLRTYRRMGRPDNYI-IGFELFKVEMNRKFRLHHLYIQERAGTSTYIDTRTVFLSKYLKKGNYVLVPTMFQHGRTSEFLLRIFSEVPVQLRELTLDMPKMSCWNLARGYPKVVTQITVHSAEDLEKKYANETVNPYLVIKCGKEEVRSPVQKNTVHAIFDTQAIFYRRT-TDIPIIVQVWNSRKFCDQFLGQVTLDAD 601          

Query:  177 LYKNQNYTKIKSQLLETNTMFTDKEFPPNLTSLFSTLSNYDLTQNEEL-NNIRWRRPGQICENPYLFVNGVSTNDVLQGRLGNCWFVAACTCITVYRENWMMLIPDYKSQEWTKEDKSEYCGIFKFRFWKYGQWTEVVIDDQLPTLENDLIYCHSNYRNEFWSALLEKAYAKILGSYEALEGGELIESLVDFTGGLAEPIVITDDHLKP--DKSSKLFQYLLKEHGNKSLIAAAIPAMTPEEQEEETSMGLIIGHAYAITMVIDLPVDTSKSDLKLVQSKVSNGHIRMMRLRNPWGQGEWKGPFCDGSPEWDVVSKSSRHRVGLTFQDDGEFWMTFIDFLNNFKSVVICHQINS-IFNKVYYESVFHSEWS------KGFSGGCLNFKNTFLDNPQYAFDINSADGEEVQFCLTQKMIRELNRNGGATGLLHIGYSILKVEANRQYRVHRLDHCLLEQSSAFKNGRSIFLRLHLKRGRYIAVPCTFQPGQIQSFMFRIYSKNSINTGELTQSLPSPGMSNYLVKVPEVATRISIFKAISLPRLDPIHGANPFFVLICENQKCISSICHGTMEPEWDESFIFYRKYFSKEPIVLLVYSRSGIIDEFIGKQAFEGN 1988
            L+KNQ Y ++K + ++   +F D  F P   SLF          N  L   + W+RP  I ++P+L V  +S + ++QGRLGN   ++A +C+ V   +W   IP++K QEW      +Y GIF FRFW +G+WTEVVIDD LPT+  DL++  S   NEFW+ALLEKAYAK+LG YEAL+G  + + ++DFTG LAE I +         ++  KLF  L K      LI  +I + + EEQE ET  GL+ G+ Y +T +  L +       +LV+   S   + M+RLRNP G+ EW GP+ + S EW  ++ + R  +GL   DDGEFWM+  DF +NF  + +C  +N+ +F +   ESV    W+         SGGC N ++TFL NPQY F +   DG +V   L QK +R   R G     + IG+ + KVE NR++R+H L       +S + + R++FL  +LK+G Y+ VP  FQ G+   F+ RI+S+  +   ELT  +P     N     P+V T+I++  A  L +       NP+ ++ C  ++  S +   T+   +D   IFYR+  +  PI++ V++     D+F+G+   + +
Sbjct:    7 LFKNQKYQELKQECMKDGRLFCDPTFLPENDSLFF---------NRLLPGKVVWKRPQDISDDPHLIVGNISNHQLIQGRLGNKAMISAFSCLAVQESHWTKAIPNHKDQEWDPRKPEKYAGIFHFRFWHFGEWTEVVIDDLLPTINGDLVFSFSTSMNEFWNALLEKAYAKLLGCYEALDGLTITDIIMDFTGTLAEIIDMQKGRYTDLVEEKYKLFGELYKTFTKGGLICCSIESPSQEEQEVETDWGLLKGYTYTMTDIRKLRLGE-----RLVEV-FSTEKLYMVRLRNPLGRQEWSGPWSEISEEWQQLTVTDRKNLGLVMSDDGEFWMSLEDFCHNFHKLNVCRNVNNPVFGRKELESVVGC-WTVDDDPLMNRSGGCYNNRDTFLQNPQYIFTV-PEDGHKVIMSLQQKDLRTYRRMGRPDNYI-IGFELFKVEMNRRFRLHHLYIQERAGTSTYIDTRTVFLSKYLKKGSYVLVPTMFQHGRTSEFLLRIFSEVPVQLRELTLDMPKMSCWNLARGYPKVVTQITVHSAEGLEKKYANETVNPYLIIKCGKEEVRSPVQKNTVHAIFDTQAIFYRRT-TDIPIIIQVWNSRKFCDQFLGQVTLDAD 601          

Query:  159 MFDKPILYKNQNYTKIKSQLLETNTMFTDKEFPPNLTSLFSTLSNYDLTQNEELNNIRWRRPGQICENPYLFVNGVSTNDVLQGRLGNCWFVAACTCITVYRENWMMLIPDYKSQEWTKEDKSEYCGIFKFRFWKYGQWTEVVIDDQLPTLENDLIYCHSNYRNEFWSALLEKAYAKILGSYEALEGGELIESLVDFTGGLAEPIVITDDHL--KPDKSSKLFQYLLKEHGNKSLIAAAIPAMTPEEQEEETSMGLIIGHAYAITMVIDLPVDTSKSDLKLVQSKVSNGHIRMMRLRNPWGQGEWKGPFCDGSPEWDVVSKSSRHRVGLTFQDDGEFWMTFIDFLNNFKSVVICHQINSIF---NKVYYESVFHSEWS-KGFSGGCLNFKNTFLDNPQYAFDINSADGEEVQFCLTQKMIRELNRNGGATGLLHIGYSILKVEANRQYRVHRLDHCLLEQSSAFKNGRSIFLRLH-LKRGRYIAVPCTFQPGQIQSFMFRIYSKNSINTGELTQSLPSPGMSNYLVKVPEVATRISIFKAISLPRLDPIHGANPFFVLICENQKCISSICHGTMEPEWDESFIFYRKYFSKEPIVLLVYSRSGIIDEFIGKQAFEGNGKEENQVLEFKLLGKKPDS 2045
            +FD    +KNQ+Y K+K +     T+F D EFPP+  SL ST   Y          + W+RP QIC +P LFV G S+ DV QG+LGNCWFVAA +C+  ++E W  +IPD K+QEW  E  + Y GIF F FW+YG W +VV+DD LPT+ + LI+ HS  +NEFWSALLEKAYAK+ G+YEAL+GGEL E+L DFTGG+++ I + +  +  KP++   LF  + KE   KSL+AA+IPA +  + E  T+ GL+ GHAY IT V ++ ++ S       + K+      M+RLRNPWG+GEWKG F DGS EW+ +SKS R ++GLTF +DGEFWMTF D+  +F    IC  +N+ +    K ++E + H +W     +GGC N + +F+ NPQY FDI + +GEE    L QK  R+   +   T    IG++ILKVE NR+YR+H L      +S+ +KN RSIFLR   +K+GRY+ +P TF PG++  ++FR+Y+  + N  ELTQ  P     N   K P + T I I +A  L + D   GA+P+ ++ CE QK  +S C  T +PEW+ S +FYRK   K P+ + +++ + I D F+GK  F      +NQ  E  L  +K +S
Sbjct:    3 LFDSVSKFKNQDYAKLKKECQTKGTLFIDTEFPPDERSLSSTPGKY--------GGVVWKRPKQICTDPKLFVEGASSGDVSQGKLGNCWFVAASSCLASFKEVWHKVIPDQKNQEWDSEKPNNYQGIFHFHFWRYGHWIDVVVDDLLPTINDQLIFIHSQSKNEFWSALLEKAYAKLFGNYEALDGGELSEALEDFTGGVSDTINLVEMEVATKPEERVALFSRMQKEMDRKSLMAASIPATSAADMEATTASGLVKGHAYGITSVKNVHLEGSGLFGLFNREKLP-----MIRLRNPWGKGEWKGAFSDGSTEWNKISKSDREKIGLTFDEDGEFWMTFEDYCKHFVQTCICRVVNTSYLSLAKTWHEGLAHGQWKVPDRAGGCPNNQESFVKNPQYMFDI-TEEGEECMIQLMQKSTRDKQGSQNVT----IGFTILKVELNREYRIHDLYLHEKIKSTVYKNSRSIFLRHGPMKKGRYVVIPSTFDPGEVAQYLFRVYTNAANNFKELTQEKPVKAWYNCCGKNPVMVTHIKIVRATGLEKQDRTGGADPYCIITCEGQKVTTSDCKSTTDPEWNVSALFYRKNPVKNPVTIQIWNNNIIKDNFMGKLVFASTDDFKNQGSEHGLTDRKNES 620          

Query:  153 FGMFDKPILYKNQNYTKIKSQLLETNTMFTDKEFPPNLTSLFSTLSNYDLTQNEELNNIRWRRPGQICENPYLFVNGVSTNDVLQGRLGNCWFVAACTCITVYRENWMMLIPDYKSQEWTKEDKSEYCGIFKFRFWKYGQWTEVVIDDQLPTLENDLIYCHSNYRNEFWSALLEKAYAKILGSYEALEGGELIESLVDFTGGLAEPIVITDDHLKPD--KSSKLFQYLLKEHGNKSLIAAAIPAMTPEEQEEETSMGLIIGHAYAITMVIDLPVDTSKSDLKLVQSKVSNGHIRMMRLRNPWGQGEWKGPFCDGSPEWDVVSKSSRHRVGLTFQDDGEFWMTFIDFLNNFKSVVICHQINSIF---NKVYYESVFHSEWSKGF-SGGCLNFKNTFLDNPQYAFDINSADGEEVQFCLTQKMIRELNRNGGATGLLHIGYSILKVEANRQYRVHRLDHCLLEQSSAFKNGRSIFLRLHLKRGRYIAVPCTFQPGQIQSFMFRIYSKNSINTGELTQSLP-SPGMSNYLVKVPEVATRISIFKAISLPRLDPIHGANPFFVLICENQKCISSICHGTMEPEWDESFIFYRKYFSKEPIVLLVYSRSGIIDEFIGKQAFEGNGKEENQVLEFKLLGKKPDSVSH--GSIFVQ 2072
             G+F  P  Y  Q Y+ ++ Q   +   F D +FPP+  SLF T          +L  + W+RP  ICENP LFV G S+ DV QG+LGNCWFVAA +C+   +  W  +IP++K QEW  +   +Y GIF F+FW+YG+W +VVIDD LPT+   L + HS  +NEFWSALLEKAYAK+ G YEAL+GG L E+L DFTGG+AE I I +     D  K  +L+    KE   +SL+AAAIPA + +E E +T  GL+ GHAY IT V  +P++ +      + +      I+M+RLRNPWG  EW G F DGSPEW+ + K  R ++GLTF+DDGEFWMTF DF   F ++ IC  +N+ F   +K ++E+ FH  W     +GGCLN K+TFL NPQY F I   + +EV   L QK      R  G    L +G+SI+KVE NR+YRVHR    +  +SSAF+N RSIFLR  LK+GRY+ +PCTF+PG+   F+ R+Y+ +  +  E+    P  P +  +    P++ T++   +A  L + D + GA+P+ ++ CE +K  + +   T+ P WD + IFYRK    +P+ + +++ + I DEF+G+  F      E+++LE  L G+K +  +   G + V+
Sbjct:    1 MGLFSSPTPYHGQVYSDLRKQAQTSGHPFIDTDFPPDDKSLFYTKG--------KLAGVEWKRPKDICENPKLFVEGTSSGDVSQGQLGNCWFVAAASCLANEKAIWQKVIPNHKDQEWDDQHPEKYGGIFHFQFWRYGEWIDVVIDDFLPTIGGQLCFVHSTSKNEFWSALLEKAYAKLFGCYEALDGGSLEEALTDFTGGIAEDINIKEGQYATDTVKQMELWDMAYKEIQRRSLMAAAIPAQSADEMEAKTDTGLVKGHAYGITAVKKVPLEGTG-----LFNFFKKDKIKMVRLRNPWGGVEWTGAFSDGSPEWEKIGKGDREKLGLTFEDDGEFWMTFDDFCTYFTNMAICRVVNTSFFSLHKAWWEAKFHGAWKNPMRAGGCLNNKDTFLRNPQYVFKITDEE-DEVMISLMQKS----GRGDGDPDKLTVGFSIMKVEENRRYRVHRPQEIV--KSSAFRNSRSIFLRHTLKKGRYVLLPCTFEPGKEGQFLLRMYTSSDNDAREMMYDSPQKPCLCCFCWSAPQMVTKVITRRATGLEKQDSVGGADPYCIISCEGEKVTTPVQKDTLNPGWDTAAIFYRKKPLTKPVKVQIWNSNNIRDEFMGQAIFVATEPCESKILEVDLYGRKNEKATKKPGKLIVE 629          

Query:  153 FGMFDKPILYKNQNYTKIKSQLLETNTMFTDKEFPPNLTSLFSTLSNYDLTQNEELNNIRWRRPGQICENPYLFVNGVSTNDVLQGRLGNCWFVAACTCITVYRENWMMLIPDYKSQEWTKEDKSEYCGIFKFRFWKYGQWTEVVIDDQLPTLENDLIYCHSNYRNEFWSALLEKAYAKILGSYEALEGGELIESLVDFTGGLAEPIVITDDHLKPD--KSSKLFQYLLKEHGNKSLIAAAIPAMTPEEQEEETSMGLIIGHAYAITMVIDLPVDTSKSDLKLVQSKVSNGHIRMMRLRNPWGQGEWKGPFCDGSPEWDVVSKSSRHRVGLTFQDDGEFWMTFIDFLNNFKSVVICHQINSIF---NKVYYESVFHSEWSKGF-SGGCLNFKNTFLDNPQYAFDINSADGEEVQFCLTQKMIRELNRNGGATGLLHIGYSILKVEANRQYRVHRLDHCLLEQSSAFKNGRSIFLRLHLKRGRYIAVPCTFQPGQIQSFMFRIYSKNSINTGELTQSLPSPG--MSNYLVKVPEVATRISIFKAISLPRLDPIH-GANPFFVLICENQKCISSICHGTMEPEWDESFIFYRKYFSKEPIVLLVYSRSGIIDEFIGKQAFEGNGKEENQVLEFKLLGKKPDSVSH--GSIFVQ 2072
             G+F  P  Y  Q Y+ ++ Q   +   F D +FPP+  SLF T          +L  + W+RP  ICENP LFV G S+ DV QG+LGNCWFVAA +C+   +  W  +IP++K QEW  +   +Y GIF F+FW+YG+W +VVIDD LPT+   L + HS  +NEFWSALLEKAYAK+ G YEAL+GG L E+L DFTGG+AE I I +     D  K  +L+    KE   +SL+AAAIPA + +E E +T  GL+ GHAY IT V  +P++ +      + +      I+M+RLRNPWG  EW G F DGSPEW+ + K  R ++GLTF+DDGEFWMTF DF   F ++ IC  +N+ F   +K ++E+ FH  W     +GGCLN K+TFL NPQY F I   + +EV   L QK      R  G    L +G+SI+KVE NR+YRVHR    +  +SSAF+N RSIFLR  LK+GRY+ +PCTF+PG+   F+ R+Y+ +  +  E+ + LP P   M  +L   P+    I +  A+ L R D    GA+P+ ++ CE +K  + +   T+ P WD + IFYRK    +P+ + +++ + I DEF+G+  F      E+++LE  L G+K +  +   G + V+
Sbjct:    1 MGLFSSPTPYHGQVYSDLRKQAQTSGHPFIDTDFPPDDKSLFYTKG--------KLAGVEWKRPKDICENPKLFVEGTSSGDVSQGQLGNCWFVAAASCLANEKAIWQKVIPNHKDQEWDDQHPEKYGGIFHFQFWRYGEWIDVVIDDFLPTIGGQLCFVHSTSKNEFWSALLEKAYAKLFGCYEALDGGSLEEALTDFTGGIAEDINIKEGQYATDTVKQMELWDMAYKEIQRRSLMAAAIPAQSADEMEAKTDTGLVKGHAYGITAVKKVPLEGTG-----LFNFFKKDKIKMVRLRNPWGGVEWTGAFSDGSPEWEKIGKGDREKLGLTFEDDGEFWMTFDDFCTYFTNMAICRVVNTSFFSLHKAWWEAKFHGAWKNPMRAGGCLNNKDTFLRNPQYVFKITDEE-DEVMISLMQKS----GRGDGDPDKLTVGFSIMKVEENRRYRVHRPQEIV--KSSAFRNSRSIFLRHTLKKGRYVLLPCTFEPGKEGQFLLRMYTSSDNDAREIIRDLPPPDLWMPCFLQTDPQQVAHIVVKNAVGLERQDTAEGGADPYCIISCEGEKVTTPVQKDTLNPGWDTAAIFYRKKPLTKPVKVQIWNSNNIRDEFMGQAIFVATEPCESKILEVDLYGRKNEKATKKPGKLIVE 631          

Query:  162 FDKPILYKNQNYTKIKSQLLETNTMFTDKEFPPNLTSLFSTLSNYDLTQNEELNNIRWRRPGQICENPYLFVNGVSTNDVLQGRLGNCWFVAACTCITVYRENWMMLIPDYKSQEWTKEDKSEYCGIFKFRFWKYGQWTEVVIDDQLPTLENDLIYCHSNYRNEFWSALLEKAYAKILGSYEALEGGELIESLVDFTGGLAEPIVITDDHLKPDKSSK--LFQYLLKEHGNKSLIAAAIPAMTPEEQEEETSMGLIIGHAYAITMVIDLPVDTSKSDLKLVQSKVSNGHIRMMRLRNPWGQGEWKGPFCDGSPEWDVVSKSSRHRVGLTFQDDGEFWMTFIDFLNNFKSVVICHQINS---IFNKVYYESVFHSEW-SKGFSGGCLNFKNTFLDNPQYAFDINSADGEEVQFCLTQKMIRELNRNGGATGLLHIGYSILKVEANRQYRVHRLDHCLLEQSSAFKNGRSIFLRLHLKRGRYIAVPCTFQPGQIQSFMFRIYSKNSINTGELTQSLPSPGMSNYL--VKVPEVATRISIFKAISLPRLDPIHGANPFFVLICENQKCISSICHGTMEPEWDESFIFYRKYFSKEPIVLLVYSRSGIIDEFIGKQAFEGNGKEENQVLEFKLLGK-----KPDSVSHGSIFVQYKT 2081
            F   +L+K+Q+Y K++ +   +  +FTD  FP N  S+    +            I W+RP  I ENP LFV+GV+ +D+ QG LGNCWFVAAC+C+   +E W  +IP++K QEW  E   +Y GI+ FRFW++G+WT+VVIDD LPT   DL+Y HS  RNEFWSALLEKAYAK+ GSYE+L+GGEL E+L DFTGG++EP+ + D  +  ++ ++  L++ + K   N +++AAAIP+ T EEQEE   MGL+ GHAY IT V  + ++ +      + +  +   I M+RLRNPWG  EWKG F D S EW  + K SR ++GLTF DDGEFWM F D+  +F ++ IC  IN+    F   + E+  H EW +  FSGGC+N K TFL NPQY FD++  D +E  F LTQK      R G       IG+SI+KVE NR+YRVH++    + +SSAFKN R IFLR  L +GRY+ V CTF+P      + R+Y+  + +   L +  PS    + L     P V TR++I +A  L + D I GA+P+  + CE     +S    T+ PEW+ S+IFYR+    +PI + +++ + + + F+G+Q    + +E +++ E  LL +     K      G IF+Q  T
Sbjct:    3 FKSVVLFKDQDYDKLRKEAQSSGQLFTDPTFPANEASIGGNAAG-----------IEWKRPKDIAENPSLFVDGVTCSDLNQGELGNCWFVAACSCLATNKEIWRKVIPNHKDQEWDPEKPEKYAGIYYFRFWRFGEWTDVVIDDLLPTRNGDLVYAHSKDRNEFWSALLEKAYAKLYGSYESLDGGELAEALEDFTGGVSEPLNLVDLKVGIEEEARNDLYKVMRKAMDNHAMMAAAIPSATKEEQEEVMDMGLVKGHAYGITAVKRIALEGTG-----IFNMFNKEKIAMIRLRNPWGGTEWKGAFSDESEEWKKIDKESREKIGLTFDDDGEFWMNFEDYCKHFTNMSICRVINTSLFSFQTTWTEACMHGEWVTPHFSGGCVNNKETFLKNPQYVFDVDDND-DECLFQLTQK----CGRGGEGIEKTTIGFSIMKVEYNRKYRVHQMQR--ITKSSAFKNSRGIFLRHTLDKGRYVIVACTFEPNVKAKHLLRVYTTGTSHAHALVKDKPSEKTLSCLPWFAYPSVVTRVTIIRARDLEKQDTIGGADPYCQISCEGHHYKTSTIKDTVNPEWNSSYIFYRRNHRSKPIEIEIWNSNALKNTFMGRQVIPASTEETDKIYEMTLLERENSKDKTSKAVPGKIFLQITT 632          

Query:  147 NLFGMFDKPILYKNQNYTKIKSQLLETNTMFTDKEFPPNLTSLFSTLSNYDLTQNEELNNIRWRRPGQICENPYLFVNGVSTNDVLQGRLGNCWFVAACTCITVYRENWMMLIPDYKSQEWTKEDKSEYCGIFKFRFWKYGQWTEVVIDDQLPTLENDLIYCHSNYRNEFWSALLEKAYAKILGSYEALEGGELIESLVDFTGGLAEPIVITDDHL--KPDKSSKLFQYLLKEHGNKSLIAAAIPAMTPEEQEEETSMGLIIGHAYAITMVIDLPVDTSKSDLKLVQSKVSNGHIRMMRLRNPWGQGEWKGPFCDGSPEWDVVSKSSRHRVGLTFQDDGEFWMTFIDFLNNFKSVVICHQINS---IFNKVYYESVFHSEWSK-GFSGGCLNFKNTFLDNPQYAFDINSADGEEVQFCLTQKMIRELNRNGGATGLLHIGYSILKVEANRQYRVHRLDHCLLEQSSAFKNGRSIFLRLHLKRGRYIAVPCTFQPGQIQSFMFRIYSKNSINTGELTQSLPSPGMSNYLVKVPEVATRISIFKAISLPRLDPIHGANPFFVLICENQKCISSICHGTMEPEWDESFIFYRKYFSKEPIVLLVYSRSGIIDEFIGKQAFEGNGKEENQVLEFKLL--GKKPDSVSHGSIFVQ 2072
            N+   F     YKNQ+Y K+K +      +F D EFPP+  SLF +          +L ++ W+RP QI +NP LFV G S  DV QGRLGNCWFVAA +C++  ++ W  +IPD++ QEW   D  +Y GIF FRFW+YG+W ++VIDD LPT+ N+L++ HS  +NEFWSALLEKAYAK+ G YEAL+GGEL E+L DFTGG++E + +    L  KP++ + LF+ + K+   KSL+AA+IPA + EE E  T +GL+ GHAY IT V ++ ++ S       + +     I M+RLRNPWG+ EWKG F DGS EW+ +SK  R ++GLTF+DDGEFWM   DF   F    IC  +N+    F+K ++E + HS+W K   +GGCLN K+TFL+NPQ+ F+I   + +E  F LTQK      R  G +  + +G+SI+KVE NR+YR+H +    +  SSAF++ R+IFLR  L +GRY  V CTF PG    F+ R+Y+ ++ N   L    P     +      ++ TR+ + +A  L R +   GA+P+ V+ CE +K  + +   T  PEW+ S IFYRK   K+P+ + +++ + + D ++GK  F    +  +++    L+  GK+ D V+ G ++VQ
Sbjct:    2 NILPCFGSMKKYKNQDYVKLKKESKAKGNLFIDLEFPPDDRSLFYSQG--------KLADVVWKRPKQITDNPKLFVEGASAGDVTQGRLGNCWFVAASSCLSANKDVWDRVIPDWQDQEWDDNDTDKYQGIFHFRFWRYGEWIDIVIDDMLPTINNELVFIHSQSKNEFWSALLEKAYAKLFGCYEALDGGELGEALEDFTGGVSEQVDLKGLDLANKPEERADLFERMKKQMDRKSLMAASIPAESSEEMEASTDIGLVKGHAYGITAVKNIHLEGSSGLFNFFRRE----KIPMVRLRNPWGEKEWKGAFSDGSAEWNKISKDDRQKIGLTFEDDGEFWMQMEDFCRYFVKAAICCVVNTSIFAFSKTWHEGLAHSKWVKPNRAGGCLNHKDTFLNNPQFTFEITDKE-DEPMFQLTQKS----TRGSGGSRNMTVGFSIIKVEENRRYRMHDMSQQEMVTSSAFRDSRAIFLRHKLTKGRYAIVACTFDPGNECDFLLRMYTSSANNFKPLIYEKPQKNWWHCCGGSIQLVTRVKVMRAEGLERQERT-GADPYCVISCEGEKVTTKVVDDTTCPEWNSSAIFYRKTALKKPLKIQIWNSNVLRDTYMGKHVFTSVDECRDKISAVGLVQRGKQGDKVASGQLYVQ 633          

Query:  159 MFDKPILYKNQNYTKIKSQLLETNTMFTDKEFPPNLTSLFSTLSNYDLTQNEELNNIRWRRPGQICENPYLFVNGVSTNDVLQGRLGNCWFVAACTCITVYRENWMMLIPDYKSQEWTKEDKSEYCGIFKFRFWKYGQWTEVVIDDQLPTLENDLIYCHSNYRNEFWSALLEKAYAKILGSYEALEGGELIESLVDFTGGLAEPIVITDDHLKPDKSSK--LFQYLLKEHGNKSLIAAAIPAMTPEEQEEETSMGLIIGHAYAITMVIDLPVDTSKSDLKLVQSKVSNGHIRMMRLRNPWGQGEWKGPFCDGSPEWDVVSKSSRHRVGLTFQDDGEFWMTFIDFLNNFKSVVICHQINSIF---NKVYYESVFHSEWS------KGFSGGCLNFKNTFLDNPQYAFDINSADGEEVQFCLTQKMIRELNRNGGATGLLHIGYSILKVEANRQYRVHRLDHCLLEQSSAFKNGRSIFLRLHLKRGRYIAVPCTFQPGQIQSFMFRIYSKNSINTGELTQSLPSPGMSNYLVKVPEVATRISIFKAISLPRLDPIHGANPFFVLICENQKCISSICHGTMEPEWDESFIFYRKYFSKEPIVLLVYSRSGIIDEFIGKQAF--EGNGKEENQVLEFKLLGKKPDSVSHGSIFVQYKT 2081
            MF     ++ Q Y+ +K Q L++ T+F D  FP    SLF         Q   +  + W+RP ++C++P+LFV+G+S +D+ QG+LGNCWFVAAC+ +      W  +IPD++ QEW  E    Y GIF FRFW++G+W +VVIDD+LPT++N L+YCHSN  NEFWSAL+EKAYAK+ G YEAL+GG   ++LVDFTGG++EP+ + +  +  D+ ++  LF+ +LK H    LI+ +I A T E+ E     GL+ GHAYA+T V    V      L   +S+     + M+R+RNPWG+ EW GP+ D S EW  VSKS R ++G+T QDDGEFWM F DF   F  +++C  IN+ +   +K + E V    W       +  SGGC+N K TFL NPQY FD+   + +EV  CL QK  R   + G    L  IG+ I +VE NR+YR+H     +    S + N R +FLR  LK GRY+ +P TF PGQ   F+ R+++    +  ELT   P       +   P++ T++ +  A  L   D    ++P+ ++ CE +K  S +   T  P +D   +F+RK   KE I + +Y+++ I+D F+G+     + N ++E   +  +  G + D+   G++ V+  T
Sbjct:    1 MFSSVKAFEGQQYSTLKKQCLQSGTLFEDPLFPAVDDSLF--------YQGNRIGRVHWKRPRELCDDPHLFVDGISAHDLHQGQLGNCWFVAACSSLASRESLWQKVIPDWREQEWDPEKDESYVGIFHFRFWRFGEWVDVVIDDRLPTVDNQLVYCHSNDSNEFWSALVEKAYAKVYGCYEALDGGNTADALVDFTGGVSEPMDLLEGQMAQDEVARNQLFERVLKVHNRDGLISCSIRATTVEDMEARLDCGLVKGHAYAVTDV--KKVRLGHGLLAFFKSE----KLHMIRMRNPWGEKEWSGPWSDSSEEWKKVSKSEREKLGVTVQDDGEFWMNFDDFCQYFTDLILCRLINTSYLSIHKTWEEEVMRGTWVYRDDPLRNRSGGCINHKATFLQNPQYVFDVRKVE-DEVLICLQQKEKRATPKEGKGENLA-IGFDIHRVELNRKYRMHSAQQKV--AGSIYINSRCVFLRKELKEGRYVIIPTTFDPGQQGEFLLRVFTDVPSDCKELTLDDPPQTCWTGMCGYPQLVTQVHVLSAEGLQGQDSNGASDPYVIITCEGEKVRSPVHKDTRCPNFDVKGVFFRKK-PKEGIHIEIYNKNVIVDTFLGQVTLFSDPNDRQEQHTVHLRDKGSRQDNDLPGTLTVRLIT 635          

Query:  159 MFDKPILYKNQNYTKIKSQLLETNTMFTDKEFPPNLTSLFSTLSNYDLTQNEELNNIRWRRPGQICENPYLFVNGVSTNDVLQGRLGNCWFVAACTCITVYRENWMMLIPDYKSQEWTKEDKSEYCGIFKFRFWKYGQWTEVVIDDQLPTLENDLIYCHSNYRNEFWSALLEKAYAKILGSYEALEGGELIESLVDFTGGLAEPIVITDDHLKPDKSSK--LFQYLLKEHGNKSLIAAAIPAMTPEEQEEETSMGLIIGHAYAITMVIDLPVDTSKSDLKLVQSKVSNGHIRMMRLRNPWGQGEWKGPFCDGSPEWDVVSKSSRHRVGLTFQDDGEFWMTFIDFLNNFKSVVICHQINSIF---NKVYYESVFHSEWS------KGFSGGCLNFKNTFLDNPQYAFDINSADGEEVQFCLTQKMIRELNRNGGATGLLHIGYSILKVEANRQYRVHRLDHCLLEQSSAFKNGRSIFLRLHLKRGRYIAVPCTFQPGQIQSFMFRIYSKNSINTGELTQSLPSPGMSNYLVKVPEVATRISIFKAISLPRLDPIHGANPFFVLICENQKCISSICHGTMEPEWDESFIFYRK 1898
            MF     ++ Q Y+ +K Q L++ T+F D  FP    SLF         Q   +  + W+RP ++C++P+LFV+G+S +D+ QG+LGNCWFVAAC+ +      W  +IPD++ QEW  E    Y GIF FRFW++G+W +VVIDD+LPT++N L+YCHSN  NEFWSAL+EKAYAK+ G YEAL+GG   ++LVDFTGG++EP+ + +  +  D+ ++  LF+ +LK H    LI+ +I A T E+ E     GL+ GHAYA+T V    V      L   +S+     + M+R+RNPWG+ EW GP+ D S EW  VSKS R ++G+T QDDGEFWM F DF   F  +++C  IN+ +   +K + E V    W       +  SGGC+N K TFL NPQY FD+   + +EV  CL QK  R   + G    L  IG+ I +VE NR+YR+H     +    S + N R +FLR  LK GRY+ +P TF PGQ   F+ R+++    +  ELT   P       +   P++ T++ +  A  L   D    ++P+ ++ CE +K  S +   T  P +D   +F+RK
Sbjct:    1 MFSSVKAFEGQQYSTLKKQCLQSGTLFEDPLFPAVDDSLF--------YQGNRIGRVHWKRPRELCDDPHLFVDGISAHDLHQGQLGNCWFVAACSSLASRESLWQKVIPDWREQEWDPEKDESYVGIFHFRFWRFGEWVDVVIDDRLPTVDNQLVYCHSNDSNEFWSALVEKAYAKVYGCYEALDGGNTADALVDFTGGVSEPMDLLEGQMAQDEVARNQLFERVLKVHNRDGLISCSIRATTVEDMEARLDCGLVKGHAYAVTDV--KKVRLGHGLLAFFKSE----KLHMIRMRNPWGEKEWSGPWSDSSEEWKKVSKSEREKLGVTVQDDGEFWMNFDDFCQYFTDLILCRLINTSYLSIHKTWEEEVMRGTWVYRDDPLRNRSGGCINHKATFLQNPQYVFDVRKVE-DEVLICLQQKEKRATPKEGKGENLA-IGFDIHRVELNRKYRMHSAQQKV--AGSIYINSRCVFLRKELKEGRYVIIPTTFDPGQQGEFLLRVFTDVPSDCKELTLDDPPQTCWTGMCGYPQLVTQVHVLSAEGLQGQDSNGASDPYVIITCEGEKVRSPVHKDTRCPNFDVKGVFFRK 573          

Query:  159 MFDKPILYKNQNYTKIKSQLLETNTMFTDKEFPPNLTSLFSTLSNYDLTQNEELNNIRWRRPGQICENPYLFVNGVSTNDVLQGRLGNCWFVAACTCITVYRENWMMLIPDYKSQEWTKEDKSEYCGIFKFRFWKYGQWTEVVIDDQLPTLENDLIYCHSNYRNEFWSALLEKAYAKILGSYEALEGGELIESLVDFTGGLAEPIVITDDHLKPDKSSK--LFQYLLKEHGNKSLIAAAIPAMTPEEQEEETSMGLIIGHAYAITMVIDLPVDTSKSDLKLVQSKVSNGHIRMMRLRNPWGQGEWKGPFCDGSPEWDVVSKSSRHRVGLTFQDDGEFWMTFIDFLNNFKSVVICHQINSIF---NKVYYESVFHSEWSK------GFSGGCLNFKNTFLDNPQYAFDINSADGEEVQFCLTQKMIRELNRNGGATGLLHIGYSILKVEANRQYRVHRLDHCLLEQSSAFKNGRSIFLRLHLKRGRYIAVPCTFQPGQIQSFMFRIYSKNSINTGELTQSLPSPGMSNYLVKVPEVATRISIFKAISLPRLDPIHGANPFFVLICENQKCISSICHGTMEPEWDESFIFYRKYFSKEPIVLLVYSRSGIIDEFIGKQAFEGN--GKEENQVLEFKLLGKKPDSVSHGSIFVQYKT 2081
            MF     Y+ Q +  ++ +  ++ T+F D  FPP   SLF         Q  ++  + W+RP ++C +P+LFVNG+S +D+ QGRLGNCWFVAAC+ +      W  +IPD+K QEW       Y GIF FRFW +G+W +VVIDD+LPT   +LIYCHSN  NEFWSAL+EKAYAKI G YEAL+GG   ++LVDFTGG++EP+ + +     ++ ++  LF  +LK H    LI+ +I A T  + E     GL+ GHAYA+T V    V      L   +S+     + M+R+RNPWG+ EW GP+ D S EW  VSK  R ++G+T QDDGEFWM F DF  +F  +++C  IN+ +   +K + E+V    WS+        SGGC+N K T+L NPQY FD+   + +EV  CL QK  R   + G    L  IG+ + +VE NR YR+H     L   SS + N RS+F+R  LK GRY+ +P TF PG    F+ R+++    +  ELT   P       L   P++ T++ + K + L   D    ++P+ ++ CE  K  S      + PE+D   +FYRK    + I + VY+++ + D F+G+    G+    +++  L  +  G + +S   G + V   T
Sbjct:    1 MFSSVKPYEGQQFEALRKRCQQSRTLFEDPLFPPVDESLF--------YQTNQIGKVTWKRPKELCSDPHLFVNGISAHDLHQGRLGNCWFVAACSSLASREALWQKVIPDWKDQEWDSNHPDSYAGIFHFRFWLFGEWVDVVIDDRLPTANGNLIYCHSNDSNEFWSALVEKAYAKIHGCYEALDGGNTADALVDFTGGVSEPVDLLEGRFGQEEEARNQLFDRVLKVHNRGGLISCSIRATTQADMEARLDCGLVKGHAYAVTDV--RRVRLGHGLLAYFKSE----KLMMIRMRNPWGEREWNGPWSDSSEEWQKVSKGEREKLGVTVQDDGEFWMMFEDFSKHFTDLILCRLINTSYLSIHKTWEEAVMMGSWSRHDDPLSNRSGGCINNKTTYLQNPQYVFDVKKPE-DEVLICLQQKDRRARPKEGKGENLA-IGFDLQRVELNRVYRMHTSQQKLC--SSVYINSRSVFVRKDLKEGRYVIIPTTFNPGLQGDFLLRVFTDVPSDCKELTLDEPPQTCWTGLCGYPQLVTQVHVMKGVGLQGQDSDGSSDPYIIISCEGVKVKSPAHKSNLSPEFDVKALFYRKK-PGQGIHIEVYNKNVLNDSFMGQVTLSGDLTDLQQHHTLHLRRKGSRQNSDLPGMLSVSVIT 635          

Query:  159 MFDKPILYKNQNYTKIKSQLLETNTMFTDKEFPPNLTSLFSTLSNYDLTQNEELNNIRWRRPGQICENPYLFVNGVSTNDVLQGRLGNCWFVAACTCITVYRENWMMLIPDYKSQEWTKEDKSEYCGIFKFRFWKYGQWTEVVIDDQLPTLENDLIYCHSNYRNEFWSALLEKAYAKILGSYEALEGGELIESLVDFTGGLAEPIVITDDHLKPDKSS--KLFQYLLKEHGNKSLIAAAIPAMTPEEQEEETSMGLIIGHAYAITMVIDLPVDTSKSDLKLVQSKVSNGHIRMMRLRNPWGQGEWKGPFCDGSPEWDVVSKSSRHRVGLTFQDDGEFWMTFIDFLNNFKSVVICHQINS---IFNKVYYESVF------HSEWSKGFSGGCLNFKNTFLDNPQYAFDINSADGEEVQFCLTQKMIRELNRNGGATGLLHIGYSILKVEANRQYRVHRLDHCLLEQSSAFKNGRSIFLRLHLKRGRYIAVPCTFQPGQIQSFMFRIYSKNSINTGELTQSLPSPGMSNYLVKVPEVATRISIFKAISLPRLDPIHGANPFFVLICENQKCISSICHGTMEPEWDESFIFYRKYFSKEPIVLLVYSRSGIIDEFIGKQAFEGNGKE--ENQVLEFKLLGKKPDSVSHGSIFVQYKTYPINEYTML 2108
            MF     YKNQ+Y+++K + L+   +F D EF  +  SLF         +      ++W+RPG +CE P LFV G+S +D+ QG +GNCWFVAAC+C+ +  + W  +IP++K QEW  +    Y GIF F+FW +G+WT+VV+DD+LPT+   LIYCHS   NEFWSALLEKAYAK+ G YE+L GG   +++VDF+G + EP+ +     + D  +  KLF  LL  +    +I+ +I A +P E+E   + GL+ GHAY++T V  + +         + +   N  + ++R+RNPWG+ EW+G + D    W  V ++        F       M+F D+  NF  V +C  +N+      K + E V       HSE  +  SGGC+N + TFL NPQY  D+   D +E+   L Q+ ++ ++R  G    L IG++I KVE NR+YR+H +       +S++ N RS+FLR  L +GRYI +P TF PG +  FM R+Y+   +   EL    PS    +  +  P+V T++ +  A  L   D   GA+P+ ++ CE     S +   T +P++D   IFYRK  +K PI + V++ + + D+F+G+       K+  + Q L+ K  G + D    G I +Q  T  + E T +
Sbjct:    1 MFSTVSAYKNQHYSELKRECLQQKKLFEDPEFLCSNRSLF--------YRTPPPGPVQWKRPG-MCEAPRLFVEGISAHDLNQGEVGNCWFVAACSCLALKPQLWQKVIPNWKEQEWDPDRPDRYTGIFHFQFWIFGEWTDVVVDDRLPTINGKLIYCHSKSNNEFWSALLEKAYAKLSGCYESLNGGNTGDAVVDFSGAVNEPVSLETGSFRTDSKTREKLFSDLLNVNDQGGIISCSI-AASPHERELRLANGLVKGHAYSVTGVRRVRLGHG------LLAYFKNDTVDLIRMRNPWGKHEWRGAWSD---RWGNVLRT----FLCVFCR-----MSFDDWCQNFTDVDVCRLMNTSVLSLQKRWREVVHFGSWIKHSEPLRNRSGGCMNHRQTFLQNPQYILDLQ--DEDELLVSLQQRDMK-IHRAHGQGENLTIGFAIFKVELNRKYRMHDIITQQNVATSSYINARSVFLRKLLPKGRYIIIPSTFTPGILGDFMLRVYANQDLICRELDVDKPSVRCWSSFMGYPQVVTQVYVHGAEGLENQDSSGGADPYVIISCEKNSIQSEVQKDTRDPQFDIRAIFYRKKPNK-PITIQVWNSNVVKDQFMGQVVLPAVLKDSADPQKLQLKKRGGQRDGEMPGKISLQIVT--VRELTAM 629          

Query:  171 PILYKNQNYTKIKSQLLETNTMFTDKEFPPNLTSLFSTLSNYDLTQNEELNNIRWRRPGQICENPYLFVNGVSTNDVLQGRLGNCWFVAACTCITVYRENWMMLIPDYKSQEWTKEDKSEYCGIFKFRFWKYGQWTEVVIDDQLPTLENDLIYCHSNYRNEFWSALLEKAYAKILGSYEALEGGELIESLVDFTGGLAEPIVITDDHLKPDKSS--KLFQYLLKEHGNKSLIAAAIPAMTPEEQEEETSMGLIIGHAYAITMVIDLPVDTSKSDLKLVQSKVSNGHIRMMRLRNPWGQGEWKGPFCDGSPEWDVVSKSSRHRVGLTFQDDGEFW--MTFIDFLNNFKSVVICHQINS---IFNKVYYESVF------HSEWSKGFSGGCLNFKNTFLDNPQYAFDINSADGEEVQFCLTQKMIRELNRNGGATGLLHIGYSILKVEANRQYRVHRLDHCLLEQSSAFKNGRSIFLRLHLKRGRYIAVPCTFQPGQIQSFMFRIYSKNSINTGELTQSLPSPGMSNYLVKVPEVATRISIFKAISLPRLDPIHGANPFFVLICENQKCISSICHGTMEPEWDESFIFYRKYFSKEPIVLLVYSRSGIIDEFIGKQAFEGNGKE--ENQVLEFKLLGKKPDSVSHGSIFVQYKTYPINEYTML 2108
            P   +NQ+Y+++K + L+   +F D EF  +  SLF         +      ++W+RPG++CE P LFV G+S +D+ QG +GNCWFVAAC+C+ +  + W  +IP++K QEW  +    Y GIF F+FW +G+WT+VV+DD+LPT+   LIYCHS   NEFWSALLEKAYAK+ G YE+L GG   +++VDF+G + EP+ +     + D  +  KLF  LL  +    +I+ +I   +P E+E   + GL+ GHAY++T V  + +         + +   N  + ++R+RNPWG+ EW+G + D              R G    DD +    M+F D+  NF  V +C  +N+      K + E V       HSE  +  SGGC+N + TFL NPQY  D+   D +E+   L Q+ ++ ++R  G    L IG++I KVE NR+YR+H +       +S++ N RS+FLR  L +GRYI +P TF PG +  FM R+Y+   +   EL    PS    +  +  P+V T++ +  A  L   D    A+P+ ++ CE     S +   T +P++D   IFYRK  +K PI + V++ + + D+F+G+       K+  + Q L+ K  G + D    G I +Q  T  + E T +
Sbjct:    3 PPETRNQHYSELKRECLQQKKLFEDPEFLCSNRSLF--------YRTPPPGPVQWKRPGEMCEAPRLFVEGISAHDLNQGEVGNCWFVAACSCLALKPQLWQKVIPNWKEQEWDPDRPDRYTGIFHFQFWIFGEWTDVVVDDRLPTINGKLIYCHSKSNNEFWSALLEKAYAKLSGCYESLNGGNTGDAVVDFSGAVNEPVSLETGSFRTDSKTREKLFSDLLNVNDQGGIISCSI--ASPHERELRLANGLVKGHAYSVTGVRRVRLGHG------LLAYFKNDTVDLIRMRNPWGKHEWRGAWSD--------------RWGEFLSDDFKLLKKMSFDDWCQNFTDVDVCRLMNTSVLSLQKRWREVVHFGSWIKHSEPLRNRSGGCMNHRQTFLQNPQYILDLQ--DEDELLVSLQQRDMK-IHRAHGQGENLTIGFAIFKVELNRKYRMHDIITQQNVATSSYINARSVFLRKLLPKGRYIIIPSTFTPGILGDFMLRVYANQDLICRELDVDKPSVRCWSSFMGYPQVVTQVYVHGAEGLENQD---SADPYVIISCEKNSIQSEVQKDTRDPQFDIRAIFYRKKPNK-PITIQVWNSNVVKDQFMGQVVLPAVLKDSADPQKLQLKKRGGQRDGEMPGKISLQIVT--VRELTAM 624          

Query:  327 IRWRRPGQICENPYLFVNGVSTNDVLQGRLGNCWFVAACTCITVYRENWMMLIPDYKSQEWTKEDKSEYCGIFKF--RFWKYGQWTEVVIDDQLPTLENDLIYCHSNYRNEFWSALLEKAYAKILGSYEALEGGELIESLVDFTGGLAEPIVITDDHLKPDKSSKLFQYLLKEHGNKSLIAAAIPAMTPEEQEEETSMGLIIGHAYAITMVIDLPVDTSKSDLKLVQSKVSNGHIRMMRLRNPWGQGEWKGPFCDGSPEWDVVSKSSRHRVGLTFQDDGEFWMTFIDFLNNFKSVVICH----QINSIFNKVYYESVFH-SEWSKG-FSGGCLNFKNTFLDNPQYAFDINSADGEEVQ---------FCLTQKMIRELNRNGGATGLLHIGYSILKV--EANRQYRVHRLDHCLLEQSSAFKNGRSIFLRLHLKRGRYIAVPCTFQPGQIQSFMFRIYSK 1649
            ++W    +I +NP   V+G +  D+ QG LG+CW +AA   +T+  +    ++P  ++       +  Y GIF F  +FW +G+W +V IDD+LPT    L++ HS  + EFWSALLEKAY+K+ GSYEAL+GG + E++ DFTGG+ E + +      PD    LF+ + K     S++  +I      E E  TS GL+ GHAY+IT V ++     K              ++++R+RNPWG+ EW G + D +PEW  + +  R+R+     +DGEFWM+F DF+ +F  + IC+    ++    +  Y+    H   W KG  +GGC NF  TF  NPQ+   +++ D E  +           L QK +R+  RN     +L +GY+I K+  +     +   L +    +S +F N R +  R  L  G Y+ VP TF+P Q   F+ R++++
Sbjct:    2 VKWGLSREIVQNPEFIVDGATRTDIKQGALGDCWLLAAIASLTLNDQLLAKVVPPGQNF------RDGYAGIFHFQQKFWHFGEWMDVFIDDRLPTKNGQLVFVHSADKREFWSALLEKAYSKLNGSYEALKGGSIAEAMEDFTGGVYELLDLKT--APPD----LFRIMCKARQKGSMMGCSIDVTNASESEARTSNGLVKGHAYSITGVDEVNYRGQK--------------VKLLRIRNPWGEVEWNGAWSDHAPEWKALDQGERNRLQQVMAEDGEFWMSFDDFMRHFTKMEICNLTPDRVEREGDPRYWTVTVHDGRWLKGCTAGGCRNFPETFWTNPQFRLKLHNEDDEADETGSKACSFIVALMQKNMRKQQRN-----MLTMGYAIYKIPDQTGPMPKEFFLYNASKARSPSFINLREVSQRFRLPAGEYVIVPSTFEPHQEADFLVRVFAE 430          

Query:  183 KNQNYTKIKSQLLETNTMFTDKEFPPNLTSLFSTLSNYDLTQNEELNNIRWRRPGQICENPYLFVNGVSTNDVLQGRLGNCWFVAACTCITVYRENWMMLIPDYKSQEWTKEDKSEYCGIFKFRFWKYGQWTEVVIDDQLPTLENDLIYCHSNYRNEFWSALLEKAYAKILGSYEALEGGELIESLVDFTGGLAEPIVITDDHLKPDKSSKLFQYLLKEHGNKSLIAAAI----------PA----------MTP------------------------EEQEEETSMGLIIGHAYAITMVIDLPVDTSKSDLKLVQSKVSNGHIRMMRLRNPWGQGEWKGPFCDGSPEWDVVSKSSRHRVGLTFQDDGEFWMTFIDFLNNFKSVVICH----QINSIFNKVYYESVFHSEWSKGFS-GGCLNFKNTFLDNPQYAFDINSADGEEVQ--------FCLTQKMIRELNRNGGATGLLHIGYSILKV-EANRQYRVHRLDHCLLEQSS-----AFKNGRSIFLRLHLKRGRYIAVPCTFQPGQIQSFMFRIYSK 1649
            + +++ ++++  L  + +F D +FP +  S++        +QN  +   +W RP ++C  P   V   +   + +G LG+CW +AA  C+T+  E    +IP  +S E        Y GIF F+FW++G+W +VV+DD+LPT  N L++  S  RNEFWSALLEKAYAK+ GSYEAL+GG   E++ DFTGG+ E   + +    P K   L++ ++K    +SL+  +I          PA          M+P                           E  T MGL+  HAY+IT      +D  K   K+VQ         ++RLRNPWG  EW GP+ D S EW+ ++ S + R+ L   +DGEFW++F DF  NF  + IC+     +       +  SV    W +G S GGC N+ +TF  NPQY   +   D +             L QK  R+  R G  + +L IG++I +V E  R  R H      L  +S     ++ N R +  R  L  G Y+ VP TF+  Q   F+ R++++
Sbjct:   49 QGKSFEELRTLCLSHDVLFEDPDFPAHNNSIY-------FSQNAPMQ-FQWMRPKELCV-PRSIVIEANHTHICEGDLGDCWVLAAIACMTMNEELLARVIPAGQSFE------ENYAGIFHFQFWRFGEWVDVVVDDRLPTFNNQLVFVQSAERNEFWSALLEKAYAKVHGSYEALKGGNTTEAMEDFTGGVTEYFEMKN----PPKD--LYKIMVKATSRRSLMGCSIDDGMCWRCGVPAPDSIGLVRSNMSPPILRHIQLTPIGIEDAKKRKIAMLTHAESRTPMGLVRNHAYSIT-----GLDEVKHRSKIVQ---------LVRLRNPWGHVEWIGPWSDASKEWNEITPSEKQRLQLISAEDGEFWISFQDFCRNFTKLEICNLSPDALADDRTNKWTVSVSEGRWVRGCSAGGCRNYPDTFWTNPQYRLQLYDEDDDPDDNELLCSFIVALMQKNRRKERRQG--STMLTIGFAIYEVTEELRGSREHLPKDFFLYNASRARCNSYINLREVTERFRLPPGEYVIVPSTFEAHQEGEFLLRVFAE 563          

Query:  183 KNQNYTKIKSQLLETNTMFTDKEFPPNLTSLFSTLSNYDLTQNEELNNIRWRRPGQICENPYLFVNGVSTNDVLQGRLGNCWFVAACTCITVYRENWMMLIPDYKSQEWTKEDKSEYCGIFKFRFWKYGQWTEVVIDDQLPTLENDLIYCHSNYRNEFWSALLEKAYAKILGSYEALEGGELIESLVDFTGGLAEPIVITDDHLKPDKSSKLFQYLLKEHGNKSLIAAAIPAMTPEEQEEE-TSMGLIIGHAYAITMVIDLPVDTSKSDLKLVQSKVSNGHIRMMRLRNPWGQGEWKGPFCDGSPEWDVVSKSSRHRVGLTFQDDGEFWMTFIDFLNNFKSVVICHQINSI----FNKVYYESVFHSEWSKGFSGGCLNFKNTFLDNP-QYAFDINSADGEEVQ---------FCLTQKMIRELNRNGGATGLLHIGYSILK-VEANRQYRVHRL-DHCLLEQSSAFKNGRSIFLRLHLKRGRYIAVPCTFQPGQIQSFMFRIYSKNS 1655
            K++ + +IK + L+   +F D +FP +L+SL   +    +TQ+   N I W+RP ++  +P   V+G +  D+ QG L +CW ++A   +T+Y +    ++P  +S         +Y GIF FRF +YG+W +V +DD+LPT + +L++  S   NEFWSALLEKAYAK+ G YEAL  G  +E+L DFTGG+ E   +       +     +  + +     ++I   I  +    + E+ T MGL+ GHAY+IT VI L              K     ++++R+RNP+G+ E+ GP+ DGS  W+ V +  + R+ +   +DGEFW++  DF  NF  V ICHQ + +       ++   + +S W KG + G       F + P  Y F +   + + V            LTQK  R+  + G     + IG  I K V   ++    +L     L +S  F   R + +R+ L  G YI +PCT   GQ   F+ RI+ + +
Sbjct:   26 KSKTFQEIKKECLQRKILFEDPDFPASLSSLHIRVQPTVITQSN--NFIEWKRPWELVRHPEFIVSGATRADINQGTLPDCWLLSAIASLTLYPDLLAKVVPMGQSFH------EDYAGIFLFRFCQYGEWVDVHVDDRLPTKKGELVFVQSGTGNEFWSALLEKAYAKLNGCYEALAYGFPVEALCDFTGGVGETFTMN------NAPRDYWDGISRAIKKGAIICCGIETLAASGRGEKVTPMGLVEGHAYSITGVIKL--------------KFPGKTVQLIRVRNPYGKVEYTGPWSDGSTTWNEVPEEDQKRLHVR-AEDGEFWISDKDFRKNFHLVEICHQGSEVEIEHRKNLWICELHNSMWLKGLNAGGSRRHRVFKEFPLNYQFFLTLLEEDNVMDVCHGCHFLLSLTQKHRRKFRKIG--IDFVPIGIYIYKAVVPGKKLTPQQLRKEKPLVESPEFIARREVTMRMTLPPGNYIIIPCTESAGQEAQFLLRIFMEKA 502          

Query:  336 RRPGQICENPYLFVNGVSTNDVLQGRLGNCWFVAACTCITVYRENWMMLIPDYKSQEWTKEDKSEYCGIFKFRFWKYGQWTEVVIDDQLPTLENDLIYCHSNYRNEFWSALLEKAYAKILGSYEALEGGELIESLVDFTGGL--------AEPIVITDDHLKPDKSSKL---------FQY------------------------------LLKEHGNKSLIAAA-IPAMTPEEQEEETSMGLIIGHAYAITMVIDLPVDTSKSDLKLVQSKVSNGHIRMMRLRNPWGQGEWKGPFCDGSPEWDVVSKSSRHRVGLTFQDDGEFWMTFIDFLNNFKSVVICHQINSIF-----NKVYYESVFHSEWSKG-FSGGCLNFKNTFLDNPQYAFDINSADGEEVQ--------FCLTQKMIRELNRNGGATGLLHIGYSILKVEANRQYRVHRLDHCLLEQSSA------FKNGRSIFLRLHLKRGRYIAVPCTFQPGQIQSFMFRIY-SKNSINTGELTQSLPSPG 1697
            R P +IC NP   VNG +  D+ QG LG+CW +AA   +T++      ++P+ +S          Y GIF F+FW++G+W +VVIDD LPT  N L + HS  RNEFWSALLEKAYAK+ GSYEAL+GG + E++ DFTGG+        A P +        +K+S +         F+Y                              L    G+  L+A++ I   +  + E     GL+ GHAY+IT               L Q       +R++R+RNPWG+ EW G + D S EW VV  S R R+     +DGEFWM+F DF  NF  + IC+           ++ +  +     W +G  +GGC N+  TF  NPQ+   ++  D +             L QK +R   R+     LL IGY+I ++          L      ++S+      F N R +  R  L  G Y+ VP T++P Q   F+ R+Y  K + + GE   +  S G
Sbjct:    1 RAPQEICYNPQFIVNGATRTDIKQGALGDCWLLAAIASLTLHPRLLARVVPEGQSFS------DGYAGIFHFQFWQFGEWVDVVIDDLLPTQNNKLAFLHSTDRNEFWSALLEKAYAKLNGSYEALKGGSIAEAMEDFTGGVFEFYNLKKAPPDLYRIMRKGLEKASMMGCSIDEGSTFKYRSTPRAINMSKMTATFRAWSSGIRRFAERFLPSRLGHARLLASSGIEITSMFDLEARLPNGLVKGHAYSIT--------------GLDQVFFEGQDVRLVRIRNPWGEVEWNGAWSDNSWEWRVVDVSERRRLEQVRAEDGEFWMSFSDFKRNFSKMEICNLSPDTLRTQSGSRHWTVTAHEGRWLRGCTAGGCRNYAGTFWTNPQFHLRLHEEDDDPDDDEVACSFIVALMQKNMRRQKRD-----LLTIGYAIYEIPLKAPPGCTHLPGEFFVRNSSRARSHNFINLREVSDRFRLPPGHYVIVPSTYEPHQEADFLLRVYCEKMNRSRGETKHNSVSKG 498          

Query:  189 QNYTKIKSQLLETNTMFTDKEFPPNLTSLFSTLSNYDLTQNEELNN-IRWRRPGQICENPYLFVNGVSTNDVLQGRLGNCWFVAACTCITVYRENWMMLIPDYKSQEWTKEDKSEYCGIFKFRFWKYGQWTEVVIDDQLPTLENDLIYCHSNYRNEFWSALLEKAYAKILGS------YEALEGGELIESLVDFTGGLAEPIVITDDHLKPDKSSKLFQYLLKEHGNKSLIAAAIPAMT--PEEQEEETSMGLIIGHAYAITMVIDLPVDTSKSDLKLVQSKVSNGH-IRMMRLRNPWGQGEWKGPFCDGSPEWDVVSKSSRHRVGLTFQDDGEFWMTFIDFLNNFKSVVICHQINSIFNK----VYYESVFHSEWSKGFS-GGCLNFKNTFLDNPQYAFDINSADGEEVQFCLTQKMIRELNRNGGATGLLHIGYSILKVEANRQYRVHRLDHCLLEQSSA------FKNGRSIFLRLHLKRGRYIAVPCTFQPGQIQSFMFRIYSKN 1652
            Q YT+I++  L    +FTD  FPP  TSL       +L    +L   + W RP +IC+NP   V+  S  D+ QG +G+CWF+AA   +T++      ++P    Q ++  D   Y GIF+FR     ++ EV    ++ T E                  L++A ++   S        A   G L       TGG           L+           L       L    +P+    P+  E ET  G+++GHAY++T V               +  +  G  + ++RLRNPWG  EW G + D +P+W+ V      R+     +DGEFWM    F  NF ++ +CH       +     +  +    EW +G S GG   +++T+  NPQY   I + +G EV   L QK  R++ RN     LL IG+ I ++  N+      L    L  +S+      + N R +  R HL  G Y+ VPCTFQP     F+ RI+++ 
Sbjct:    1 QVYTRIRADCLRLRRLFTDDLFPPEATSL----GYAELGAGSKLARAVVWSRPEEICKNPQFIVDDASRFDLCQGEVGDCWFLAALASVTLHPRLLERVLPS--QQSFSAVDG--YAGIFRFRVRSVSKYLEVSRGAEVATAEA-----------------LKQAASQPCPSATSSCCLAARSTGGLYCCCCCSTGGFYCCCGTGRSWLEKGALGAFCPAAL------GLCCGGVPSGLSFPKRPEVETKDGIVLGHAYSVTGV---------------EKVIYRGQSVELVRLRNPWGCVEWSGDWSDRAPQWNEVDPRVMQRMRNAL-EDGEFWMYMGHFRKNFHTLDMCHLTADDLAEGQRHRWAVATHAGEWRRGHSAGGTCQYQDTYRTNPQYRVRILAREGGEVLLTLLQKP-RDMQRN--RQPLLSIGFLIHQIPKNKAATTLHLPQEALTAASSVGGTATWSNLREVGGRFHLPYGDYVVVPCTFQPNDEAEFILRIFAQR 459          

Query:  180 YKNQNYTKIKSQLLETNTMFTDKEFPPNLTSLFSTLSNYDLTQNEELNNIRWRRPGQICEN--PYLFVNGVSTNDVLQGRLGNCWFVAACTCITVYRENWMMLIPDYKSQEWTKEDKSEYCGIFKFRFWKYGQWTEVVIDDQLPTLENDLIYCHSNYRNEFWSALLEKAYAKILGSYEALEGGELIESLVDFTGGLAEPIVITDDHLKPDKSSK--LFQYLLKEHGNKSLIAAAIPAMTPEEQEEETSMGLIIGHAYAITMVIDLPVDTSKSDLKLVQSKVSNGHIRMMRLRNPWGQGEWKGPFCDGSPEWDVVSKSSRHRVGLTFQDDGEFWMTFIDFLNNFKSVVICHQIN-SIFNKVYYESVFHSE---WSKG-FSGGCLNFKNTFLDNPQYAFDINSADGEEVQFCLTQKMIRELNRNGGATGLLHIGYSILKVEANRQYRVHRLDHCLLEQSSAFKNGRSIFLRLHLKRGRYIAVPCTFQPGQIQSFMFRIYSKNSINTGELTQSLPSPGMSNYL----VKVPEVATRISIFKAISLPRLDPIH-GANPFFVLICENQKCISSICHGTMEPEWDESFIFYRKYFSKEPIVLLVYSRSGIIDEFIGKQAFEGNGKEENQVLEFKLLGKKP--DSVSHGSIFVQYKTY 2084
            + NQ Y+K+K++  +   +F D  F P  +SL+ + S            + W+RP +IC    P+LFV+G  ++DV QG+LGNCWFVAAC+ + +       +IPD   QEW  +    Y GIF+FRF++ G+WTEVV+DD LPT+   L+Y HS  +NEFWSAL+EKAYAK+ G+YEAL  G   ++LVDFTGG+AE I +++     D+  +  LF+ L + H  KSL++A+I      E E+    GLI GHAY +TMV  + V   +  L L   K    H  M+RLRNPWG+ EW G + D S EW  +    R ++G+ F++DGEFWM F DF   F    +CH IN ++ +KV+ +   +     W++G  +GGC+  ++TFL NPQYAF I   +GE+    L Q+  R+    G   G L IG+ I+KVE NR+YRVH +        S F N R +  R  L  GRY+ VP T++P     FM RI+++   N   L Q   S G   +      + P+    + +  A  L +   +    +P+ ++ICE +K  + I + T+ P WD   +FY +   K  IV+ ++  + I+D F+G+     N         + L G++   D    G++ VQ   Y
Sbjct:    7 FANQRYSKLKAECEKNEQLFVDSVFKPETSSLYYSRSC-------PPEPVEWKRPSEICHPAVPHLFVDGADSHDVTQGKLGNCWFVAACSSLALRPFLLYKVIPDKDKQEWDPKKPENYQGIFRFRFYRQGEWTEVVVDDLLPTVNGKLVYIHSKEKNEFWSALIEKAYAKLAGTYEALAAGSTADALVDFTGGVAEAISLSNGGYAEDQEKRLQLFKTLERGHKEKSLMSASIKINNRNEMEQRLDTGLIKGHAYGVTMVKKVTV--GEGLLSLFNKK----HFYMIRLRNPWGEKEWNGRWSDESEEWKKLKPGDRKKMGIVFENDGEFWMEFDDFCREFTDCTLCHVINKAMIHKVFKQWHIYKHNYNWTQGQNAGGCVQNQDTFLKNPQYAFSITDNEGEDAMVSLMQEDRRKDKSKG--VGNLTIGFYIMKVEENRKYRVHSM--FPKAGDSIFINAREVMNRFFLAAGRYLVVPSTYEPHTPGHFMMRIFTRKRSNAMFLDQD-HSVGSKIWCCLPRCRAPQCVVSVYVTSAAGLQKTGKMSLTCDPYALIICEGRKIKTPIKYDTLIPSWDAGALFYVRQPQKSQIVVQIWDSNWILDSFMGQVKIPVNITNSKTQASYNLKGRRREHDLQKPGTVTVQINAY 639          

Query:  186 NQNYTKIKSQLLETNTMFTDKEFPPNLTSLFSTLSNYDLTQNEELNNIRWRRPGQICENPYLFVNGVSTNDVLQGRLGNCWFVAACTCITVYRENWMMLIP-DYKSQEWTKEDKSEYCGIFKFRFWKYGQWTEVVIDDQLPTLENDLIYCHSNYRNEFWSALLEKAYAKILGSYEALEGGELIESLVDFTGGLAEPIVITDDHLKPDKSSKLFQYLLKEHGNKSLIAAAIPAMTPEEQEEETSMGLIIGHAYAITMVIDLPVDTSKSDLKLVQSKVSNGHIRMMRLRNPWG-QGEWKGPFCDGSPEWDVVSKSSRHRVGLTFQDDGEFWMTFIDFLNNFKSVVICH-QINSIF--NKVYYESVF-HSEWSKGF-SGGCLNFKNTFLDNPQYAFDINSADGEEVQFC-----LTQKMIRELNRNGGATGLLHIGYSILKVEANRQYRVHRLD------HCLLEQSSAFKNGRSIFLRLHLKRGRYIAVPCTFQPGQIQSFMFRIYSKNSINTGELTQ 1679
            N     ++ Q+  T   F D EF    +S+F +                W+RP  ICE+P++FV G S  D+ QG LG+CW +AA   +T +      ++P DY +      +   Y G  KF  W+YG+W +V+IDD+LPT    L++ HS+ RNEFWSALLEKAYAK+ GSYE+L+GG+  E+L DFTGGLAE        L  +    LF  +       +L+  +I A    E E + + GL+ GHAY +T    +   T + DL           + ++R+RNPWG + EWKG + DGS EW ++S   +  +GLTF+DDGEFWM+F DF  +F ++ IC    +S    + V +ES   H  W +G  +GGC NF  TF  NPQ+   +  +D +    C     L QK  R+  ++G     L IG+SI K+E  +  +   LD      H    +S  F N R +  R  L  G Y+ +P TF P +  +F+ R+YS+ +  T E+ +
Sbjct:    3 NLTMDDVRRQVRSTGKPFEDDEFLAIDSSIFFS--------KRPPRPFEWKRPSDICEDPHMFVGGASRLDIQQGMLGDCWLLAAIAALTQHSALMNKVVPQDYVANP----NDRNYTGALKFCIWQYGEWKDVIIDDRLPTYNGKLVFVHSSERNEFWSALLEKAYAKLNGSYESLKGGQTGEALEDFTGGLAESF-----DLNKNVPKDLFCIMQTAEKRHALMGCSIAA-KANEIEAKLNNGLVKGHAYTVTGCRQVKAKTRRGDL----------DVELVRVRNPWGNEREWKGAWGDGSSEWQLLSDYEKKSIGLTFEDDGEFWMSFDDFKKHFTTLEICMLGADSAMEGSSVGFESRSEHGMWRRGLTAGGCRNFIKTFHKNPQFRITLQDSDDDADDLCTVIIALMQKDRRKEKKHG--INPLTIGFSIYKLEEEKD-KQGNLDMEFFQYHASTARSPVFINSREVVGRYALPPGEYVVIPTTFNPNEEGNFVLRMYSEKAHKTCEVDE 487          

Query:  168 KPILYKNQNYTKIKSQLLETNTMFTDKEFPPNLTSLFSTLSNYDLTQNEELNNIRWRRPGQICENPYLFVNGVSTNDVLQGRLGNCWFVAACTCITVYRENWMMLIPDYKSQEWTKEDKSEYCGIFKFRFWKYGQWTEVVIDDQLPTLENDLIYCHSNYRNEFWSALLEKAYAKILGSYEALEGGELIESLVDFTGGLAEPIVITDDHLKPDKSSKLFQYLLKEHGNKSLIAAAIPAMTPEEQEEETSM--GLIIGHAYAITMVIDLPVDTSKSDLKLVQSKVSNGHIRMMRLRNPWG-QGEWKGPFCDGSPEWDVVSKSSRHRVGLTFQDDGEFWMTFIDFLNNFKSVVIC----HQINSIFNKVYYESVFHSEWSKGF-SGGCLNFKNTFLDNPQYAFDINSADGEEVQFC--LTQKMIRELNRNGGATGLLHIGYSILKVEANRQYRVHRLDHCLLE------QSSAFKNGRSIFLRLHLKRGRYIAVPCTFQPGQIQSFMFRIYSKNSINTGELTQ 1679
            +  L+K + +  ++ QLL +  +F D++FP +   LF+   +  L          W+RP +I ++P     G S++DV QGR+ NCWFVAA   +T   +    + P  +S E        YCG+F+F FW++G+W E+++DD LPT    L +  S+  +EFWSALLEKAYAK+ GSYEA+  G + E+L D TGG+ E + +       +    LF  ++K +  +SL+  +I        + E ++  GLI  HAY+IT +        K+ L  ++ +     + ++RLRNP     EW+G + D SPEW+++S   +  + LTF DDGEFWM+F DFLNNF  + IC      +     + +        W KG  +GGC NF  +F  NPQ+   + + D ++ + C  +   M  + +          IG++I K  ++ + +  RLD    E       +++F   R I  R  L  G Y+ +P TF PGQ   F+ RI+S+      E+ Q
Sbjct:    3 RRALHKRERFASLQRQLLNSKRLFEDRDFPASNRVLFTRRRSVQLI---------WKRPHEISKSPQFIARGFSSSDVAQGRIRNCWFVAALADLTTNIDLLHHVCPPDQSFE-----PGSYCGMFRFNFWQFGEWVEIIVDDYLPTYNGRLYFTKSDDPDEFWSALLEKAYAKLCGSYEAMSLGRISEALQDMTGGMIENVDLQ------NPPHGLFNVMMKAYERQSLMGCSIEVKKYSSDQYEGTLENGLITRHAYSITGL-------RKATLSSLRGR---PEVDLIRLRNPHANSSEWRGAWSDRSPEWNMLSSQEKRELNLTFDDDGEFWMSFDDFLNNFTRLEICMLTPDSMEQNDRRKWDVQNEKGRWQKGVTAGGCRNFIASFYTNPQFRVCLKNPDDDDDELCTVIVSLMRVDHSHRVKIPDRAPIGFAIYKAPSDMR-KGDRLDRAFFEYNKAVAMTTSFSKLREISSRYRLHAGEYVVIPSTFNPGQEGDFLLRIFSERPQYASEIDQ 491          

Query:  348 QICENPYLFVNGVSTNDVLQGRLGNCWFVAACTCITVYRENWMMLIPD--YKSQEWTKEDKSEYCGIFKFRFWKYGQWTEVVIDDQLPTLENDLIYCHSNYRNEFWSALLEKAYAKILGSYEALEGGELIESLVDFTGGLAEPIVITDDHLKPDKSSKLFQYLLKEHGNKSLIAAAIPAMTPEEQEEETSMGLIIGHAYAITMVIDLPVDTSKSDLKLVQSKVSNGHIRMMRLRNPWG-QGEWKGPFCDGSPEWDVVSKSSRHRVGLTFQDDGEFWMTFIDFLNNFKSVVICH-QINSIFNKVYYESVFHSEWSKGF------SGGCLNFKNTFLDNPQY 1337
            +IC  P  +V+G S  D+ QG LGNCW +AA + +  ++     ++P+  Y++  ++      Y G   F+ W+YG+W  V+IDD+LPT +  L++ HS  +NEFW ALLEKAYAKI GSYEAL+GG   E+L DFTGGL+E  V+       D  + LFQ + +     +L+  +I                                              + G + ++R+RNPWG + EW G + D SPEW  +S+  +  + L F  DGEFWM+F DF ++F  + +C   + +  +K   +  F+S    GF      +GGC NF  TF  NPQ+
Sbjct:   12 EICSEPRFYVDGASRLDIKQGVLGNCWLLAAMSVLAQHKPLVDRIMPEGVYEADRFS----PRYTGKVVFKLWQYGEWVTVIIDDRLPTYKGKLVFVHSPEKNEFWCALLEKAYAKIHGSYEALKGGLTGEALEDFTGGLSEVFVL------EDAPANLFQIMQRAEKRSALMGCSINVFLS-----------------------------------------TRGGVELIRIRNPWGDEKEWTGAWGDRSPEWQELSQDEKRSLDLEFDVDGEFWMSFEDFKSHFDKLEVCMLDVENAIDKT--QISFNSRLENGFWRKHVSAGGCRNFLETFHTNPQF 298          

Query: 1443 IGYSILKVE--ANRQYRVHRLDHCLLE-----QSSAFKNGRSIFLRLHLKRGRYIAVPCTFQPGQIQSFMFRIYSKNSINTGELTQS--LPSPGMSNYLVKVPEVATRISIF 1751
            IG+++ K++    R+Y V RLD    +     + S F N R +  R  L  G Y+ VP TF       F+ RI+S+ ++++  LT+S    S G+    +K    A +  +F
Sbjct:  393 IGFALYKIDDITKRKYGVSRLDKEYFQFNKSTERSTFINSREVVGRFELAPGEYVIVPSTFIQNAEADFLLRIFSEKAVSSSALTESTFFGSLGIDQVDLKDMNDAEKFRVF 504          

Query:  237 FTDKEFPPNLTSLFSTLSNYDLTQNEELNNIRWRRPGQI-----CEN--PYLFVNGVSTNDVLQGRLGNCWFVAACTCITVYRENWMMLIPDYKSQEWTKEDKSEYCGIFKFRFWKYGQWTEVVIDDQLPTLENDLIYCHSNYRNEFWSALLEKAYAKILGSYEALEGGELIESLVDFTGGLAEPIVITDDH-----LKPDKSSKLFQYLLKEHGNKSLIAAAIPAMT-PEEQEEETSMGLIIGHAYAITMVIDLPVDTSKSDLKLVQSKVSNGHIRMMRLRNPWGQGEWKGPFCDGSPEWDVVSKSSRHRVGLTFQDDGEFWMTFIDFLNNFKSVVICHQINSIFNKVYYESVFHSEWSKGFSGGCLNFKNTFLDNPQYAFDINSADGEEVQFCLTQKMIR 1403
            F D  FPP L SL+      +   +E      W RP +I     C    P+        +D++QG LG+CWF+++   + V  E   +L     ++E + +      G ++ R  K G+WT ++IDD LP  +         +R + W  L+EKA AK+ GSYEAL  G  IE L   TG   E I + +        +P     ++  L+       L+ A+    T PEE+    ++GL   HAY++  V D+                 +G IR++RLRNPWGQ  W G + D S  W   +   RH + +    +G FWM+  DF+  F SV +C   +S              W+     GC      F   P     +      E+  CL Q  IR
Sbjct:   44 FVDDSFPPVLKSLY-----INPRHSEHPRVADWLRPNEIDNFSTCRTNIPWAVFRNPRPSDIIQGVLGDCWFLSS---LAVLAERPELLEKILITREVSPQ------GAYQVRLCKDGKWTVILIDDLLPCNQRGQPVYSWAHRRQLWVPLIEKAMAKLHGSYEALTAGRSIEGLATLTGAPCESIALHESQNNSGNTEPIDKDLIWAQLISSRTAGFLMGASCGGDTQPEEEPGYNAVGLQTHHAYSVLDVRDV-----------------HG-IRLLRLRNPWGQYSWTGDWSDASSLW---TPELRHELMVHGAQEGVFWMSLEDFMKYFDSVDVCKIRDS--------------WADVRVTGCF---PPFAAGPAKVAMVTVFSPTELDLCLFQTGIR 393          

Query:  159 MFDKPILYKNQNYTKIKSQLLETNTMFTDKEFPPNLTSLFSTLSNYDLTQNEELNNIRWRRPGQICENPYLFVNGVSTNDVLQGRLGNCWFVAACTCITVYRENWMMLIPDYKSQEWTKEDKSEYCGIFKFRFWKYGQWTEVVIDDQLPTLENDLIYCHSNYRNEFWSALLEKAYAKILGSYEALEGGELIESLVDFTGGLAEPIVITDDHLKPDKSSK--LFQYLLKEHGNKSLIAAAIPAMTPEEQEEETSMGLIIGHAYAITMVIDLPVDTSKSDLKLVQSKVSNGHIRMMRLRNPWGQGEWKGPFCDGSPEWDVVSKSSRHRVGLTFQDDGEFWMTFIDFLNNFKSVVICHQINSIF---NKVYYESVFHSEWS------KGFSGGCLNFKNTFLDNPQYAFDINSADGEEVQFCLTQKMIRELNRNGGATGLLHIGYSILKVEANRQYRVHRLDHCLLEQSSAFKNGRSIFLRLHLKRGRYIAVPCTFQPGQIQSFMFRIYSKNSINTGELTQSLPSPGMSNYLVKVPEVATRISIFKAISLPRLDPIHGANPFFVLICENQKCISSICHGTMEPEWDESFIFYRKYFSKEPIVLLVYSRSGIIDEFIGKQAF--EGNGKEENQVLEFKLLGKKPDSVSHGSIFVQYKT 2081
            MF     +  Q Y+ +K Q L++  +F D  FP    SLF  L N        +  + W+RP ++CE+P+LFV+G+S +D+ QG+LGNCWFVAAC+ +      W  +IPD+K QEW  E    Y GIF FRFW++G+W +VVIDD+LPT++N L+YCHSN  NEFWSAL+EKAYAK+ G YEAL+GG   ++LVDFTGG++EP+ + +  +  D++++  LF+ +LK H    LI+ +I A T E+ E     GL+ GHAYA+T V    V      L   +S+     ++M+R+RNPWG+ EW GP+ D S EW+ VSKS R ++G+T QDDGEFWMTF DF   F  +++C  IN+ +   +K + E V    W       +  +GGC+N K+TFL NPQY FD+   + +EV  CL QK  R   + G    L  IG+ I +VE NR+YR+H     +    S + N R +FLR  +K GRY+ +P TF PGQ   F+ R+++    +  ELT   P       +   P++ T++ +  A  L   D     + + V+ CE ++  S +   T  P +D   +FYRK   KE I + VY+R+ I+D F+G+     + N ++E   L  +  G + D+   G++ V+  T
Sbjct:   73 MFTSVKAFDGQQYSTLKRQCLQSGLLFEDPRFPAIDDSLF-YLGN-------RIGRVVWKRPRELCEDPHLFVDGISAHDLHQGQLGNCWFVAACSSLASRESLWQKVIPDWKEQEWDTEKPDSYTGIFHFRFWRFGEWVDVVIDDRLPTVDNQLVYCHSNDSNEFWSALVEKAYAKVYGCYEALDGGNTADALVDFTGGVSEPVDLLEGQMATDEAARNQLFERVLKVHNRDGLISCSIRATTVEDMEARLDCGLVKGHAYAVTDV--RKVRLGHGLLAFFKSE----KLQMIRMRNPWGEKEWSGPWSDSSEEWNKVSKSEREKLGVTVQDDGEFWMTFDDFCQYFTDLILCRLINTSYLSIHKTWEEEVIRGLWVHRQDPLRNRAGGCINHKSTFLQNPQYVFDVKKLE-DEVLICLQQKERRATPKEGKGENLA-IGFDIHRVELNRKYRMHTAQQKV--AGSIYINSRCVFLRKEMKEGRYVIIPTTFDPGQQGEFLLRVFTDVPSDCKELTLDEPPQTCWTGMCGYPQLVTQVHVLNAEGLQGQDSNGAVDSYVVITCEGERVRSPVQKDTRCPNFDFKGLFYRKK-PKEGIHIEVYNRNMIVDTFLGQVILFSDPNERQEQHTLHLRDKGNRQDNNLPGTLTVRLIT 707          

Query:  159 MFDKPILYKNQNYTKIKSQLLETNTMFTDKEFPPNLTSLFSTLSNYDLTQNEELNNIRWRRPGQICENPYLFVNGVSTNDVLQGRLGNCWFVAACTCITVYRENWMMLIPDYKSQEWTKEDKSEYCGIFKFRFWKYGQWTEVVIDDQLPTLENDLIYCHSNYRNEFWSALLEKAYAKILGSYEALEGGELIESLVDFTGGLAEPIVITDDHLKPDKSSK--LFQYLLKEHGNKSLIAAAIPAMTPEEQEEETSMGLIIGHAYAITMVIDLPVDTSKSDLKLVQSKVSNGHIRMMRLRNPWGQGEWKGPFCDGSPEWDVVSKSSRHRVGLTFQDDGEFWMTFIDFLNNFKSVVICHQINSIF---NKVYYESVFHSEWS------KGFSGGCLNFKNTFLDNPQYAFDINSADGEEVQFCLTQKMIRELNRNGGATGLLHIGYSILKVEANRQYRVHRLDHCLLEQSSAFKNGRSIFLRLHLKRGRYIAVPCTFQPGQIQSFMFRIYSKNSINTGELTQSLPSPGMSNYLVKVPEVATRISIFKAISLPRLDP---IHGANP--------------FFVLICENQKCISSICHGTMEPEWDESFIFYRKYFSKEPIVLLVYSRSGIIDEFIGKQAF--EGNGKEENQVLEFKLLGKKPDSVSHGSIFVQYKT 2081
            MF     +  Q Y+ +K Q L++  +F D  FP    SLF  L N        +  + W+RP ++CE+P+LFV+G+S +D+ QG+LGNCWFVAAC+ +      W  +IPD+K QEW  E    Y GIF FRFW++G+W +VVIDD+LPT++N L+YCHSN  NEFWSAL+EKAYAK+ G YEAL+GG   ++LVDFTGG++EP+ + +  +  D++++  LF+ +LK H    LI+ +I A T E+ E     GL+ GHAYA+T V    V      L   +S+     ++M+R+RNPWG+ EW GP+ D S EW+ VSKS R ++G+T QDDGEFWMTF DF   F  +++C  IN+ +   +K + E V    W       +  +GGC+N K+TFL NPQY FD+   + +EV  CL QK  R   + G    L  IG+ I +VE NR+YR+H     +    S + N R +FLR  +K GRY+ +P TF PGQ   F+ R+++    +  ELT   P       +   P++ T++ +  A  L   D    +H  NP              + V+ CE ++  S +   T  P +D   +FYRK   KE I + VY+R+ I+D F+G+     + N ++E   L  +  G + D+   G++ V+  T
Sbjct:   73 MFTSVKAFDGQQYSTLKRQCLQSGLLFEDPRFPAIDDSLF-YLGN-------RIGRVVWKRPRELCEDPHLFVDGISAHDLHQGQLGNCWFVAACSSLASRESLWQKVIPDWKEQEWDTEKPDSYTGIFHFRFWRFGEWVDVVIDDRLPTVDNQLVYCHSNDSNEFWSALVEKAYAKVYGCYEALDGGNTADALVDFTGGVSEPVDLLEGQMATDEAARNQLFERVLKVHNRDGLISCSIRATTVEDMEARLDCGLVKGHAYAVTDV--RKVRLGHGLLAFFKSE----KLQMIRMRNPWGEKEWSGPWSDSSEEWNKVSKSEREKLGVTVQDDGEFWMTFDDFCQYFTDLILCRLINTSYLSIHKTWEEEVIRGLWVHRQDPLRNRAGGCINHKSTFLQNPQYVFDVKKLE-DEVLICLQQKERRATPKEGKGENLA-IGFDIHRVELNRKYRMHTAQQKV--AGSIYINSRCVFLRKEMKEGRYVIIPTTFDPGQQGEFLLRVFTDVPSDCKELTLDEPPQTCWTGMCGYPQLVTQVHVLNAEGLQGQDSNGELHCLNPQKKRLLGKAQAVDSYVVITCEGERVRSPVQKDTRCPNFDFKGLFYRKK-PKEGIHIEVYNRNMIVDTFLGQVILFSDPNERQEQHTLHLRDKGNRQDNNLPGTLTVRLIT 724          

Query:  174 ILYKNQNYTKIKSQLLETNTMFTDKEFPPNLTSLFSTLSNYDLTQNEELNNIRWRRPGQICENPYLFVNGVSTNDVLQGRLGNCWFVAACTCITVYRENWMMLIPDYKSQEWTKEDKSEYCGIFKFRFWKYGQWTEVVIDDQLPTLENDLIYCHSNYRNEFWSALLEKAYAKILGSYEALEGGELIESLVDFTGGLAEPIVITDDHLKPD--KSSKLFQYLLKEHGNKSLIAAAIPAMTPEEQEEETSMGLIIGHAYAITMVIDLPVDTSKSDLKLVQSKVSNGHIRMMRLRNPWGQGEWKGPFCDGSPEWDVVSKSSRHRVGLTFQDDGEFWMTFIDFLNNFKSVVICHQINSIF---NKVYYESVFHSEWS------KGFSGGCLNFKNTFLDNPQYAFDINSADGEEVQFCLTQKMIRELNRNGGATGLLHIGYSILKVEANRQYRVHRLDHCLLEQSSAFKNGRSIFLRLHLKRGRYIAVPCTFQPGQIQSFMFRIYSKNSINTGELTQSLPSPGMSNYLVKVPEVATRISIFKAISLPRLDPIHGANPFFVLICENQKCISSICHGTMEPEWDESFIFYRKYFSKEPIVLLVYSRSGIIDEFIGKQAFEGNGKEENQVLEFKLLGKKPDSVSHGSIFVQYKTYPI 2090
            + Y+ Q+++ ++ +  +   +F D  FPP+  SLF         +   +  + W+RPG++  +P+LFV+G+S +D+ QG+LGNCWFVAAC+ +      W  +IPD+K QEW KE    Y GIF FRFW++G+W +VVIDD LPT+   L+Y HSN  NEFWSAL+EKAYAK+ G YEAL+GG   ++LVDFTGG++EPI +  +  K D  K  +LF+ +LK H    LI+ +I A +  + E     GL+ GHAYA+T V    V      L   +S      + M+R+RNPWGQ EW GP+ D S EW  VSKS R ++G+T  DDGEFWMTF DFL NF  +++C  IN+ +   +K + E V    W       +  +GGC N K++   NPQY FD+   + +EV  CL QK  R   + G     L IG+ I KVE NR YR+H     +    S + N R++FLR+ LK+GRY+ VP TF+ G    F+ RI++    N  ELT   P     + L   P + T++ + +A  L   D    ++P+ ++ CE Q+  S +   T  P +D   +FYRK  SK+PI + +Y+ +   D F+GK           +    K  G + D+   G++ +  +T  +
Sbjct:    3 VPYEGQSFSALRKRCQQKGCLFEDPLFPPSDKSLF--------YEGNRVGQVVWKRPGELSSDPHLFVDGISAHDLHQGQLGNCWFVAACSSLASREALWQKVIPDWKEQEWDKEKPQSYAGIFHFRFWRFGEWVDVVIDDLLPTVSGQLLYGHSNDHNEFWSALVEKAYAKMFGCYEALDGGNTADALVDFTGGVSEPIDLIQNGYKEDDEKRDELFERVLKVHNRGGLISCSIRATSAADMEARLGCGLVKGHAYAVTDV--RRVRLGHGLLAFFKSD----KLSMIRMRNPWGQKEWNGPWSDSSEEWKKVSKSEREKMGVTVDDDGEFWMTFDDFLTNFTDLILCRLINTSYLSLHKTWEEVVVRGSWRRHDEPLRNRAGGCSNNKHSHFQNPQYVFDVTKPE-DEVMVCLQQKDRRATLKEGRGEN-LPIGFDIQKVELNRVYRMHAAQQKV--GGSIYINSRAVFLRIDLKKGRYVIVPTTFEAGLEGEFLLRIFTDVPSNCRELTLDEPRRSCWSGLRGYPSLVTQVYVQQANGLAGQDSDRVSDPYVIIRCEGQEVRSDVHKNTCSPVFDTKALFYRKK-SKQPISVEIYNHNVFKDSFLGKVTLPAEEGTLQKTFHLKNKGDRQDNDLPGTVTLSIETSSV 633          

Query:  174 ILYKNQNYTKIKSQLLETNTMFTDKEFPPNLTSLFSTLSNYDLTQNEELNNIRWRRPGQICENPYLFVNGVSTNDVLQGRLGNCWFVAACTCITVYRENWMMLIPDYKSQEWTKEDKSEYCGIFKFRFWKYGQWTEVVIDDQLPTLENDLIYCHSNYRNEFWSALLEKAYAKILGSYEALEGGELIESLVDFTGGLAEPIVITDDHLKPDKSSK--LFQYLLKEHGNKSLIAAAIPAMTPEEQEEETSMGLIIGHAYAITMVIDLPVDTSKSDLKLVQSKVSNGHIRMMRLRNPWGQGEWKGPFCDGSPEWDVVSKSSRHRVGLTFQDDGEFWMTFIDFLNNFKSVVICHQINSIF---NKVYYESVFHSEWSK------GFSGGCLNFKNTFLDNPQYAFDINSADGEEVQFCLTQKMIRELNRNGGATGLLHIGYSILKVEANRQYRVHRLDHCLLEQSSAFKNGRSIFLRLHLKRGRYIAVPCTFQPGQIQSFMFRIYSKNSINTGELTQSLPSPGMSNYLVKVPEVATRISIFKAISLPRLDPIHGANPFFVLICENQKCISSICHGTMEPEWDESFIFYRKYFSKEPIVLLVYSRSGIIDEFIGKQAFEGNGKEENQVLEFKL 2024
            + +KNQ Y  +K + ++   +F D EFP + +SLF         +      + W+RP +I  +P+LFV G++++D+ QG +GNCWFVAA +C+ +    W  +IPD++ QEW  +    Y GIF F+FW +GQWT+VV+DD+LPT+   LIYCHSN + EFWSALLEKAYAK+ G YE+L GG   +++VDFTG + E I +  +    D+ ++  LF+ LLK + +  +I+  I A  P E E + + GL+ GHAY++T V  + +         + +      I M+R+RNPWG+ EW GP+ D S EW  +  + RH +GLT +DDGEFWM+F D+   F    +C  IN+     +K + E +    W+K         GGC N  NTFL NPQY FD+ + + EEV   L QK  R   + G     L IG+S+LKVE NR+YR+HRL      +SS F N RS+F+R  L +GRYI +P TFQ G++  FM RI++       ELT+  P       L   P+  T + + KA  L   D   GA+P+ ++ CE +   S +   T+ P++D S +FYRK  SK PI + V++ + + DEF+G+    G+ K+  Q L+ +L
Sbjct:    6 VPFKNQRYADLKRESIQRKILFRDPEFPADDSSLF--------YKEPPPGKVEWKRPWKISSDPHLFVEGINSHDLYQGEIGNCWFVAASSCLAMMPHLWQKVIPDWQEQEWDPKHPENYAGIFHFQFWVFGQWTDVVVDDRLPTINGKLIYCHSNSKKEFWSALLEKAYAKLYGCYESLSGGFAGDAVVDFTGAVYERIDLEREAFYKDQRNQDYLFENLLKVYEHGGIISCGITA-EPHELEFKMANGLVKGHAYSVTAVKRIHLRHE------LVAHFKTETIPMIRMRNPWGKMEWNGPWSDSSEEWSKIGDTERHNLGLTVEDDGEFWMSFEDWCKKFTDADVCSIINTSLVSIHKTWSEVLHFGSWTKHGDPLLNRCGGCGN-NNTFLQNPQYMFDV-TKEIEEVLITLQQKDRRTFKKTGQGEN-LSIGFSVLKVELNRKYRIHRLLSQKSMESSVFINARSVFVRCILPQGRYIIIPSTFQAGELGEFMLRIFTDVDSGCRELTEDKPKVKCWTPLFGYPQAVTHVFVEKAERLENQDRTAGADPYVIISCEGKSVKSIVHKDTLNPQFDTSAVFYRKKPSK-PITVEVWNSNAVADEFMGQVVLPGSPKDSQQKLKLQL 614          

Query:  174 ILYKNQNYTKIKSQLLETNTMFTDKEFPPNLTSLFSTLSNYDLTQNEELNNIRWRRPGQICENPYLFVNGVSTNDVLQGRLGNCWFVAACTCITVYRENWMMLIPDYKSQEWTKEDKSEYCGIFKFRFWKYGQWTEVVIDDQLPTLENDLIYCHSNYRNEFWSALLEKAYAKILGSYEALEGGELIESLVDFTGGLAEPIVITDDHLKPDKSSK--LFQYLLKEHGNKSLIAAAIPAMTPEEQEEETSMGLIIGHAYAITMVIDLPVDTSKSDLKLVQSKVSNGHIRMMRLRNPWGQGEWKGPFCDGSPEWDVVSKSSRHRVGLTFQDDGEFWMTFIDFLNNFKSVVICHQINSIF---NKVYYESVFHSEWSK------GFSGGCLNFKNTFLDNPQYAFDINSADGEEVQFCLTQKMIRELNRNGGATGLLHIGYSILKVEANRQYRVHRLDHCLLEQSSAFKNGRSIFLRLHLKRGRYIAVPCTFQPGQIQSFMFRIYSKNSINTGELTQSLPSPGMSNYLVKVPEVATRISIFKAISLPRLDPIHGANPFFVLICENQKCISSICHGTMEPEWDESFIFYRKYFSKEPIVLLVYSRSGIIDEFIGKQAFEGNGKEENQVLEFKL 2024
            + +KNQ Y  +K + ++   +F D EFP + +SLF         +      + W+RP +I  +P+LFV G++++D+ QG +GNCWFVAA +C+ +    W  +IPD++ QEW  +    Y GIF F+FW +GQWT+VV+DD+LPT+   LIYCHSN + EFWSALLEKAYAK+ G YE+L GG   +++VDFTG + E I +  +    D+ ++  LF+ LLK + +  +I+ +I A  P+E E + + GL+ GHAY++T V  + +         + +      + M+R+RNPWG+ EW G + D S EW  +  + RH +GLT +DDGEFWM+F D+   F    +C  IN+     +K + E +    W+K         GGC N  NTFL NPQY FD+ + + EEV   L QK  R   + G     L IG+S+LKVE NR+YR+HRL      +SS F N RS+F+R  L +GRYI +P TFQ G++  FM RI++       ELT+  P       L   P+  T + + KA  L   D   GA+P+ ++ CE +   S +   T+ P++D S +FYRK  SK PI + V++ + + DEF+G+    G+ K+  Q L+ +L
Sbjct:    6 VPFKNQRYADLKRESIQRKILFRDPEFPADDSSLF--------YKEPPPGKVEWKRPWKISSDPHLFVEGINSHDLYQGEIGNCWFVAASSCLAMMPHLWQKVIPDWQEQEWDPKHPENYAGIFHFQFWVFGQWTDVVVDDRLPTINGKLIYCHSNSKKEFWSALLEKAYAKLYGCYESLSGGFAGDAVVDFTGAVYERIDLEREAFYKDQRNQDYLFENLLKVYEHGGIISCSIKA-KPDELEFKMANGLVKGHAYSVTAVKRIHL------CHELVAHFKTETLPMIRMRNPWGKMEWNGAWSDSSEEWSKIGDTERHNLGLTVEDDGEFWMSFEDWCKKFTDADVCSIINTSLVSIHKTWSEVLHFGSWTKHGDPLLNRCGGCGN-NNTFLQNPQYMFDV-TKEIEEVLITLQQKDRRTFKKTGQGEN-LSIGFSVLKVELNRKYRIHRLLSQKSMESSVFINARSVFVRCILPQGRYIIIPSTFQAGELGEFMLRIFTDVDSGCRELTEDKPKVKCWTPLFGYPQAVTHVFVEKAERLENQDRTAGADPYVIISCEGKSVKSIVHKDTLNPQFDTSAVFYRKKPSK-PITVEVWNSNAVADEFMGQVVLPGSPKDSQQKLKLQL 614          

Query:  693 LGSYEALEGGELIESLVDFTGGLAEPIVITDDHLKPDKSSKLFQYLLKEHGNKSLIAAAIPAMTPEEQEEETSMGLIIGHAYAITMVIDLPVDTSKSDLKLVQSKVSNGHIRMMRLRNPWGQGEWKGPFCDGSPEWDVVSKSSRHRVGLTFQDDGEFWMTFIDFLNNFKSVVICHQINSIFNKVYYESVFHSEWSKGFSGGCLNFKNTFLDNPQYAFDINSADGEEVQFCLTQKMIRELNRNGGATGLLHIGYSILKVEANRQYRVHRLDHCLLEQSSAFKNGRSIFLRLHLKRGRYIAVPCTFQPGQIQSFMFRIYSKNSINTGELTQSLPSPGMSNYLVKVPEVATRISIFKAISLPRLDPIHGANPFFVLICENQKCISSICHGTMEPEWDESFIFYRKYFSKEPIVLLVYSRSGIIDEFIGKQAFEGNGKEENQVLEFKLLGKKPDSVSHGSIFVQYKTYPINEYTML 2108
            + SYEALEGGELIESLVDFTGGLAEPIVITDDHLKPDKSSKLFQYLLKEHGNKSLIAAAIPAMTPEEQEEETSMGLIIGHAYAITMVIDLPVDTSKSDLKLVQSKVSNGHIRMMRLRNPWGQGEWKGPFCDGSPEW+VVSKSSRHRVGLTFQDDGEFWMTFIDFLNNFKSVVICHQINSIFNKVYYESVFHSEWSKGFSGGCLNFKNTFLDNPQYAFDINSADGEEVQFCLTQKMIRELNRNGGATGLLHIGYSILKVEANRQYRVHRLDHCLLEQSSAFKNGRSIFLRLHLKRGRYIAVPCTFQPGQIQSFMFRIYSKNSINTGELTQSLPSPGMSNYLVKVPEVATRISIFKAISLPRLDPIHGANPFFVLICENQKCISSICHGTMEPEWDESFIFYRKYFSKEPIVLLVYSRSGIIDEFIGKQAFEGN KEENQVLEFKLLGKKPDSVSHGSIFVQYKTYPINEYTML
Sbjct:   38 IASYEALEGGELIESLVDFTGGLAEPIVITDDHLKPDKSSKLFQYLLKEHGNKSLIAAAIPAMTPEEQEEETSMGLIIGHAYAITMVIDLPVDTSKSDLKLVQSKVSNGHIRMMRLRNPWGQGEWKGPFCDGSPEWEVVSKSSRHRVGLTFQDDGEFWMTFIDFLNNFKSVVICHQINSIFNKVYYESVFHSEWSKGFSGGCLNFKNTFLDNPQYAFDINSADGEEVQFCLTQKMIRELNRNGGATGLLHIGYSILKVEANRQYRVHRLDHCLLEQSSAFKNGRSIFLRLHLKRGRYIAVPCTFQPGQIQSFMFRIYSKNSINTGELTQSLPSPGMSNYLVKVPEVATRISIFKAISLPRLDPIHGANPFFVLICENQKCISSICHGTMEPEWDESFIFYRKYFSKEPIVLLVYSRSGIIDEFIGKQAFEGNSKEENQVLEFKLLGKKPDSVSHGSIFVQYKTYPINEYTML 509          

Query:  660 SALLEKAY--AKILGSYEALEGGELIESLVDFTGGLAEPIVITDDHLKPDKSSKLFQYLLKEHGNKSLIAAAIPAMTPEEQEEETSMGLIIGHAYAITMVIDLPVDTSKSDLKLVQSKVSNGHIRMMRLRNPWGQGEWKGPFCDGSPEWDVVSKSSRHRVGLTFQDDGEFWMTFIDFLNNFKSVVICHQINSIFNKVYYESVFHSEWSKGFSGGCLNFKNTFLDNPQ---------------------YAFDINSADGEEVQFCLTQKMIRELNRNGGATGLLHIGYSILKVEANRQYRVHRLDHCLLEQSSAFKNGRSIFLRLHLKRGRYIAVPCTFQPGQIQSFMFRIYSKNSINTGELTQSLPSPGMSNYLVKVPEVATRISIFKAISLPRLDPIHGANPFFVLICENQKCISSICHGTMEPEWDESFIFYRKYFSKEPIVLLVYSRSGIIDEFIGKQAFEGNGKEENQVLEFKLLGKKPDSVSHGSIFVQYKTYPINEYTML 2108
            S L++K +   +ILGSYEALEGGELIESLVDFTGGLAEPIVITDDHLKPDKSSKLFQYLLKEHGNKSLIAAAIPAMTPEEQEEETSMGLIIGHAYAITMVIDLPVDTSKSDLKLVQSKVSNGHIRMMRLRNPWGQGEWKGPFCDGSPEW+VVSKSSRHRVGLTFQDDGEFWMTFIDFLNNFKSVVICHQINSIFNKVYYESVFHSEWSKGFSGGCLNFKNTFLDNPQ                     YAFDINSADGEEVQFCLTQKMIRELNRNGGATGLLHIGYSILKVEANRQYRVHRLDHCLLEQSSAFKNGRSIFLRLHLKRGRYIAVPCTFQPGQIQSFMFRIYSKNSINTGELTQSLPSPGMSNYLVKVPEVATRISIFKAISLPRLDPIHGANPFFVLICENQKCISSICHGTMEPEWDESFIFYRKYFSKEPIVLLVYSRSGIIDEFIGKQAFEGN KEENQVLEFKLLGKKPDSVSHGSIFVQYKTYPINEYTML
Sbjct:    8 SILMDKLWLNIEILGSYEALEGGELIESLVDFTGGLAEPIVITDDHLKPDKSSKLFQYLLKEHGNKSLIAAAIPAMTPEEQEEETSMGLIIGHAYAITMVIDLPVDTSKSDLKLVQSKVSNGHIRMMRLRNPWGQGEWKGPFCDGSPEWEVVSKSSRHRVGLTFQDDGEFWMTFIDFLNNFKSVVICHQINSIFNKVYYESVFHSEWSKGFSGGCLNFKNTFLDNPQGSVRLPLLRVQLYGSDFVLLAYAFDINSADGEEVQFCLTQKMIRELNRNGGATGLLHIGYSILKVEANRQYRVHRLDHCLLEQSSAFKNGRSIFLRLHLKRGRYIAVPCTFQPGQIQSFMFRIYSKNSINTGELTQSLPSPGMSNYLVKVPEVATRISIFKAISLPRLDPIHGANPFFVLICENQKCISSICHGTMEPEWDESFIFYRKYFSKEPIVLLVYSRSGIIDEFIGKQAFEGNSKEENQVLEFKLLGKKPDSVSHGSIFVQYKTYPINEYTML 513          

Query:  693 LGSYEALEGGELIESLVDFTGGLAEPIVITDDHLKPDKSSKLFQYLLKEHGNKSLIAAAIPAMTPEEQEEETSMGLIIGHAYAITMVIDLPVDTSKSDLKLVQSKVSNGHIRMMRLRNPWGQGEWKGPFCDGSPEWDVVSKSSRHRVGLTFQDDGEFWMTFIDFLNNFKSVVICHQINSIFNKVYYESVFHSEWSKGFSGGCLNFKNTFLDNPQ--------------------------YAFDINSADGEEVQFCLTQKMIRELNRNGGATGLLHIGYSILKVEANRQYRVHRLDHCLLEQSSAFKNGRSIFLRLHLKRGRYIAVPCTFQPGQIQSFMFRIYSKNSINTGELTQSLPSPGMSNYLVKVPEVATRISIFKAISLPRLDPIHGANPFFVLICENQKCISSICHGTMEPEWDESFIFYRKYFSKEPIVLLVYSRSGIIDEFIGKQAFEGNGKEENQVLEFKLLGKKPDSVSHGSIFVQYKTYPINEYTML 2108
            + SYEALEGGELIESLVDFTGGLAEPIVITDDHLKPDKSSKLFQYLLKEHGNKSLIAAAIPAMTPEEQEEETSMGLIIGHAYAITMVIDLPVDTSKSDLKLVQSKVSNGHIRMMRLRNPWGQGEWKGPFCDGSPEW+VVSKSSRHRVGLTFQDDGEFWMTFIDFLNNFKSVVICHQINSIFNKVYYESVFHSEWSKGFSGGCLNFKNTFLDNPQ                          YAFDINSADGEEVQFCLTQKMIRELNRNGGATGLLHIGYSILKVEANRQYRVHRLDHCLLEQSSAFKNGRSIFLRLHLKRGRYIAVPCTFQPGQIQSFMFRIYSKNSINTGELTQSLPSPGMSNYLVKVPEVATRISIFKAISLPRLDPIHGANPFFVLICENQKCISSICHGTMEPEWDESFIFYRKYFSKEPIVLLVYSRSGIIDEFIGKQAFEGN KEENQVLEFKLLGKKPDSVSHGSIFVQYKTYPINEYTML
Sbjct:   38 IASYEALEGGELIESLVDFTGGLAEPIVITDDHLKPDKSSKLFQYLLKEHGNKSLIAAAIPAMTPEEQEEETSMGLIIGHAYAITMVIDLPVDTSKSDLKLVQSKVSNGHIRMMRLRNPWGQGEWKGPFCDGSPEWEVVSKSSRHRVGLTFQDDGEFWMTFIDFLNNFKSVVICHQINSIFNKVYYESVFHSEWSKGFSGGCLNFKNTFLDNPQPVEHKGSVRLPLLRVQLYGSDFVLLAYAFDINSADGEEVQFCLTQKMIRELNRNGGATGLLHIGYSILKVEANRQYRVHRLDHCLLEQSSAFKNGRSIFLRLHLKRGRYIAVPCTFQPGQIQSFMFRIYSKNSINTGELTQSLPSPGMSNYLVKVPEVATRISIFKAISLPRLDPIHGANPFFVLICENQKCISSICHGTMEPEWDESFIFYRKYFSKEPIVLLVYSRSGIIDEFIGKQAFEGNSKEENQVLEFKLLGKKPDSVSHGSIFVQYKTYPINEYTML 535          

Query:  138 MTANLFGMFDKPILYKNQNYTKIKSQLLETNTMFTDKEFPPNLTSLFSTLSNYDLTQNEELNNIRWRRPGQICENPYLFVNGVSTNDVLQGRLGNCWFVAACTCITVYRENWMMLIPDYKSQEWTKEDKSEYCGIFKFRFWKYGQWTEVVIDDQLPTLENDLIYCHSNYRNEFWSALLEKAYAK 689
            MTANLFGMFDKPILYKNQNYTKIKSQLLETNTMFTDKEFPPNLTSLFSTLSNYDLTQNEELNNIRW+RPGQICENPYLFVNGVSTNDVLQGRLGNCWFVAACTCITVYRENWMMLIPDYKSQEWTKEDKSEYCGIFKFRFWKYGQWTEVVIDDQLPTLENDLIYCHSNYRNEFWSALLEKAYAK
Sbjct:    1 MTANLFGMFDKPILYKNQNYTKIKSQLLETNTMFTDKEFPPNLTSLFSTLSNYDLTQNEELNNIRWKRPGQICENPYLFVNGVSTNDVLQGRLGNCWFVAACTCITVYRENWMMLIPDYKSQEWTKEDKSEYCGIFKFRFWKYGQWTEVVIDDQLPTLENDLIYCHSNYRNEFWSALLEKAYAK 184          

Query:  189 QNYTKIKSQLLETNTMFTDKEFPPNLTSLFSTLSNYDLTQNEELNNIRWRRPGQICENPYLFVNGVSTNDVLQGRLGNCWFVAACTCITVYRENWMMLIPDYKSQEWTKEDKSEYCGIFKFRFWKYGQWTEVVIDDQLPTLENDLIYCHSNYRNEFWSALLEKAYAKILGSYEALEGGELIESLVDFTGGLAEPIVITDDHLKPDKSS-KLFQYLLKEHGNKSLIAAAIPAMTPEEQEEETSMGLIIGHAYAITMVIDLPVDTSKSDLKLVQSKVS--NGH-IRMMRLRNPWGQGEWKGPFCDGSPEWDVVSKSSRHRVGLTFQDDGEFWMTFIDFLNNFKSVVICH---------QINSIFNKVYYESVFHSEWSKGFS-GGCLNFKNTFLDNPQYAFDINSADGEE------VQFCLTQKMIRELNRNGGATGLLHIGYSILKVEANRQ-------YRVHRLDHCLLEQSSAFKNGRSIFLRLHLKRGRYIAVPCTFQPGQIQSFMFRIYSKNSINTGELTQSLPSPGMSNYLVKVP----EVATRISIFKAIS 1763
            ++Y  +K +L+   T++ D++FP N  S++ T        + +  N +W+RP +IC +P  FV G S  DV QG LG+CW +AA   +++    +  + P+ +S       K +YCG F F FW YG+W E++IDD+LPT  N L++ HS   NEFWSALLEKAYAK+ GSYE L+GG   E++ DFTGG+ E I +  D+ K ++S  KLFQ +++ H   SL+  +I A  P+  E +   GLI+GHAY+IT V            K + +KV   NG  I+++R+RNPWGQ EW G + D S  W  +S   R  +GL F +DGEFWM+F DF+NNF+ + ICH          + +   + +  SV    W KG S GGCLNF+ TF  NPQ+   +   D ++      V   L QK +R +   G    L  IGY + K+ +          +R +R     +  S AF N R +  R  L  G Y  +P TF+  Q   F+ RI+S+ + N G+           N ++ VP    E+    S FKA++
Sbjct:   90 ESYDSLKEKLVAKGTLYEDEDFPANGESIYFT--------SNKGGNFQWKRPHEICSDPQFFVGGASRFDVCQGELGDCWLLAAVASLSMQTMLFSQVAPNDQSFA-----KGKYCGAFHFNFWHYGEWKEIIIDDRLPTRNNRLVFMHSRDSNEFWSALLEKAYAKLCGSYELLKGGSSSEAMEDFTGGITEIIDLKGDNRKNNESKEKLFQIMIQSHSKMSLMGCSIDA-NPKVTEAKLGNGLIMGHAYSITAV------------KQISAKVPGYNGDIIKLVRIRNPWGQSEWNGEWGDSSDSWHHISDKERGVLGLNFDNDGEFWMSFNDFVNNFEKLEICHLGPQSVGESLLKNSNKRTWESSVQQGAWKKGASAGGCLNFQETFWSNPQFRIVVTDPDKDDTDNMGTVIIGLLQKNMRSIKNRG--NDLFPIGYVLYKLPSTDCGPLDKVFFRTNR----KVAMSPAFINMREVCGRHRLPPGSYAIIPSTFEVNQEADFLLRIFSERA-NCGKEIDETSKMDDKNLVLPVPVNESEIEQLRSAFKAVA 612