Serine/threonine kinase receptor associated protein

Overview


Name	Serine/threonine kinase receptor associated protein
Smed ID	SMED30027898
Length (bp)	889

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of Serine/threonine kinase receptor associated protein (SMED30027898) t-SNE clustered cells

Violin plots show distribution of expression levels for Serine/threonine kinase receptor associated protein (SMED30027898) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Serine/threonine kinase receptor associated protein (SMED30027898) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30027898

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 2

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication	Specimen	Lifecycle	Evidence
X1 cell	SMED30027898	SMESG000035983.1	SmedASXL_010639	SmedAsxl_ww_GCZZ01	PMID:26114597 Zhu et al., 2015
X2 cell	SMED30027898	SMESG000035983.1	SmedASXL_010639	SmedAsxl_ww_GCZZ01	PMID:26114597 Zhu et al., 2015

Note: Hover over icons to view figure legend

Homology

[Close]

BLAST of Serine/threonine kinase receptor associated protein vs. Ensembl Human
Match: STRAP (serine/threonine kinase receptor associated protein [Source:HGNC Symbol;Acc:HGNC:30796])

HSP 1 Score: 147.517 bits (371), Expect = 2.939e-41
Identity = 86/168 (51.19%), Postives = 114/168 (67.86%), Query Frame = 3

Query:  174 ALRQNSIQCSGHTRPVVDLHFSRLNDDKTYYVISASKDSVPMLRFGHTGDWIGSFKGHKGAVWSCTLSNDASKAATGAADFTAKVWDCENGKAITSIDHNHIVRCVDFNETANQLVTATNKFGIEIHDLKSPGKPIMNFNGHTDMIHRTMWLNDDQKIISVSKDKTIR 677
            A+RQ  + CSGHTRPVVDL FS +     Y++ISA KD  PMLR G TGDWIG+F GHKGAVW  TL+ DA+KAAT AADFTAKVWD  +G  + ++ H HIV+ VDF + +N L+T      + I+DL  P       +GHT  I + +W ++D++I+S + DKT+R
Sbjct:    2 AMRQTPLTCSGHTRPVVDLAFSGITP-YGYFLISACKDGKPMLRQGDTGDWIGTFLGHKGAVWGATLNKDATKAATAAADFTAKVWDAVSGDELMTLAHKHIVKTVDFTQDSNYLLTGGQDKLLRIYDLNKPEAEPKEISGHTSGIKKALWCSEDKQILS-ADDKTVR 167

[Close]

BLAST of Serine/threonine kinase receptor associated protein vs. Ensembl Human
Match: STRAP (serine/threonine kinase receptor associated protein [Source:HGNC Symbol;Acc:HGNC:30796])

HSP 1 Score: 138.272 bits (347), Expect = 1.242e-37
Identity = 86/181 (47.51%), Postives = 114/181 (62.98%), Query Frame = 3

Query:  174 ALRQNSIQCSGHTRPVVDLHFSRLNDDKTYYVISASK-------------DSVPMLRFGHTGDWIGSFKGHKGAVWSCTLSNDASKAATGAADFTAKVWDCENGKAITSIDHNHIVRCVDFNETANQLVTATNKFGIEIHDLKSPGKPIMNFNGHTDMIHRTMWLNDDQKIISVSKDKTIR 677
            A+RQ  + CSGHTRPVVDL FS +     Y++ISA K             D  PMLR G TGDWIG+F GHKGAVW  TL+ DA+KAAT AADFTAKVWD  +G  + ++ H HIV+ VDF + +N L+T      + I+DL  P       +GHT  I + +W ++D++I+S + DKT+R
Sbjct:    2 AMRQTPLTCSGHTRPVVDLAFSGITP-YGYFLISACKGAGQHLPRLSGQHDGKPMLRQGDTGDWIGTFLGHKGAVWGATLNKDATKAATAAADFTAKVWDAVSGDELMTLAHKHIVKTVDFTQDSNYLLTGGQDKLLRIYDLNKPEAEPKEISGHTSGIKKALWCSEDKQILS-ADDKTVR 180

[Close]

BLAST of Serine/threonine kinase receptor associated protein vs. Ensembl Human
Match: EIF3I (eukaryotic translation initiation factor 3 subunit I [Source:HGNC Symbol;Acc:HGNC:3272])

HSP 1 Score: 67.3958 bits (163), Expect = 1.971e-13
Identity = 34/115 (29.57%), Postives = 59/115 (51.30%), Query Frame = 3

Query:  192 IQCSGHTRPVVDLHFSRLNDDKTYYVISASKDSVPMLRFGHTGDWIGSFKGHKGAVWSCTLSNDASKAATGAADFTAKVWDCENGKAITSIDHNHIVRCVDFNETANQLVTATNK 536
            I   GH R +  + ++R  D     + + +KD +  + +   G+ +G++ GH GAVW      D     TG+AD + ++WDCE GK +  +  N  VR   F+   N ++ +T+K
Sbjct:    4 ILLQGHERSITQIKYNREGD----LLFTVAKDPIVNVWYSVNGERLGTYMGHTGAVWCVDADWDTKHVLTGSADNSCRLWDCETGKQLALLKTNSAVRTCGFDFGGNIIMFSTDK 114

[Close]

BLAST of Serine/threonine kinase receptor associated protein vs. Ensembl Human
Match: EIF3I (eukaryotic translation initiation factor 3 subunit I [Source:HGNC Symbol;Acc:HGNC:3272])

HSP 1 Score: 68.1662 bits (165), Expect = 1.711e-12
Identity = 42/155 (27.10%), Postives = 72/155 (46.45%), Query Frame = 3

Query:  192 IQCSGHTRPVVDLHFSRLNDDKTYYVISASKDSVPMLRFGHTGDWIGSFKGHKGAVWSCTLSNDASKAATGAADFTAKVWDCENGKAITSIDHNHIVRCVDFNETANQLVTATNK-FG----IEIHDLKSPGK-----PIMNFNGHTDMIHRTMW 626
            I   GH R +  + ++R  D     + + +KD +  + +   G+ +G++ GH GAVW      D     TG+AD + ++WDCE GK +  +  N  VR   F+   N ++ +T+K  G    +   DL+ P +     P M    +   I   +W
Sbjct:    4 ILLQGHERSITQIKYNREGD----LLFTVAKDPIVNVWYSVNGERLGTYMGHTGAVWCVDADWDTKHVLTGSADNSCRLWDCETGKQLALLKTNSAVRTCGFDFGGNIIMFSTDKQMGYQCFVSFFDLRDPSQIDNNEPYMKIPCNDSKITSAVW 154

[Close]

BLAST of Serine/threonine kinase receptor associated protein vs. Ensembl Human
Match: NLE1 (notchless homolog 1 [Source:HGNC Symbol;Acc:HGNC:19889])

HSP 1 Score: 63.929 bits (154), Expect = 1.265e-11
Identity = 46/178 (25.84%), Postives = 86/178 (48.31%), Query Frame = 3

Query:  150 TMEKLNNKAL-RQNSIQCSGHTRPVVDLHFSRLNDDKTYYVISASKDSVPMLRFGHTGDWIGSFKGHKGAVWSCTLSNDASKAATGAADFTAKVWDCENGKAITSI-DHNHIVRCVDFNETANQLVTATNKFGIEIHDLKSPGKPIMNFNGHTDMIHRTMWLNDDQKIISVSKDKTIR 677
            ++++L  +AL R N ++  G  R V        +DD T ++ S ++D  P+ R            GH+  +     S D+   A+ + D + K+WD   GK + S+  H   V  + ++  +  LV+ ++   +++ D+K+  K  M+  GH D ++   W  D Q++ S  KDK +R
Sbjct:   29 SLQELKERALSRYNLVRGQGPERLVSG------SDDFTLFLWSPAEDKKPLTRM----------TGHQALINQVLFSPDSRIVASASFDKSIKLWDGRTGKYLASLRGHVAAVYQIAWSADSRLLVSGSSDSTLKVWDVKAQ-KLAMDLPGHADEVYAVDWSPDGQRVASGGKDKCLR 189

[Close]

BLAST of Serine/threonine kinase receptor associated protein vs. Ensembl Celegans
Match: eif-3.I (Eukaryotic translation initiation factor 3 subunit I [Source:UniProtKB/Swiss-Prot;Acc:Q965S8])

HSP 1 Score: 73.1738 bits (178), Expect = 1.329e-14
Identity = 39/135 (28.89%), Postives = 65/135 (48.15%), Query Frame = 3

Query:  192 IQCSGHTRPVVDLHFSRLNDDKTYYVISASKDSVPMLRFGHTGDWIGSFKGHKGAVWSCTLSNDASKAATGAADFTAKVWDCENGKAITSIDHNHIVRCVDFNETANQLVTATNKF-----GIEIHDLKSPGKPI 581
            +   GH R +  + F+R  D       S +KD  P + +   G+ IGS+ GH GAVW   +S D +K  T + D T K+WD E G  + +I+H   ++   F+ + N +   T K        ++ DL+   + +
Sbjct:    4 LSLKGHERALTRVRFNREGD----LTFSCAKDKKPCVWYTENGERIGSYDGHNGAVWDIDVSWDTTKCVTASGDLTVKIWDAELGNCLYTINHQTPMKSCGFSYSGNLVCFTTQKMTKNLSTFQVRDLRDSSQMV 134

[Close]

BLAST of Serine/threonine kinase receptor associated protein vs. Ensembl Celegans
Match: qui-1 (QUInine non-avoider [Source:UniProtKB/TrEMBL;Acc:N1NTL8])

HSP 1 Score: 54.6842 bits (130), Expect = 3.887e-8
Identity = 47/157 (29.94%), Postives = 71/157 (45.22%), Query Frame = 3

Query:  246 NDDKTYYVISASKDSVPMLRFGHTGDWIGSFKGHKGAVWSCTLSNDASKAATGAADFTAKVWDCENGK---------------AITSIDHNHIVRCVDFNETANQLVTATNKFGIEIHDLKSPGKPIMNFNGHTDMIHRTMWLNDDQKIISVSKDKT 671
            +DD+  Y+I+AS DS   +    TG+ + SF  H G+V S  L+++     TG+ DF  ++WD  NGK               AITS D   +V C D  ET     T     G E+H+L           GH   ++  +   DD ++ + +K K 
Sbjct:  963 SDDQ--YLITASADSSAKMIKLETGEVMRSFNDHTGSVVSLQLTSNNQFLITGSGDFVVQMWDVTNGKCISRMGGLMAPVSTLAITSNDAFVVVACED--ETLKVFSTVG---GQELHELM----------GHEGKVNSLVCAQDDCQLFAATKSKV 1102

[Close]

BLAST of Serine/threonine kinase receptor associated protein vs. Ensembl Celegans
Match: qui-1 (QUInine non-avoider [Source:UniProtKB/TrEMBL;Acc:N1NTL8])

HSP 1 Score: 54.6842 bits (130), Expect = 4.794e-8
Identity = 47/156 (30.13%), Postives = 71/156 (45.51%), Query Frame = 3

Query:  246 NDDKTYYVISASKDSVPMLRFGHTGDWIGSFKGHKGAVWSCTLSNDASKAATGAADFTAKVWDCENGK---------------AITSIDHNHIVRCVDFNETANQLVTATNKFGIEIHDLKSPGKPIMNFNGHTDMIHRTMWLNDDQKIISVSKDK 668
            +DD+  Y+I+AS DS   +    TG+ + SF  H G+V S  L+++     TG+ DF  ++WD  NGK               AITS D   +V C D  ET     T     G E+H+L           GH   ++  +   DD ++ + +K K
Sbjct:  698 SDDQ--YLITASADSSAKMIKLETGEVMRSFNDHTGSVVSLQLTSNNQFLITGSGDFVVQMWDVTNGKCISRMGGLMAPVSTLAITSNDAFVVVACED--ETLKVFSTVG---GQELHELM----------GHEGKVNSLVCAQDDCQLFAATKSK 836

[Close]

BLAST of Serine/threonine kinase receptor associated protein vs. Ensembl Celegans
Match: W07E6.2 (pep chromosome:WBcel235:II:480722:483104:-1 gene:WBGene00021074.1 transcript:W07E6.2b.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:W07E6.2)

HSP 1 Score: 50.447 bits (119), Expect = 9.774e-8
Identity = 36/122 (29.51%), Postives = 59/122 (48.36%), Query Frame = 3

Query:  165 NNKALRQNSIQCSGHTRPVVDLHFSRLNDDKTYYVISASKDSVPMLRFGHTGDWIGSFKGHKGAVWSCTLSNDASKAATGAADFTAKVWDCENGKAITSID-HNHIVRCVDFNETANQLVTA 527
            N K  +Q+  + +GH + V  + FS      T Y+ SAS D    L  G TG ++ S +GH G V+    S D+    +G+AD T KV++ +       +  H   V  VD++    ++V+ 
Sbjct:    3 NPKETKQSINRMTGHMQLVNQVVFS----PDTRYIASASFDKSVKLWCGRTGKYLASLRGHVGPVYQVAWSADSRLLVSGSADSTLKVFELKTKSLYYDLPGHGDEVFTVDWSPEGTKVVSG 120

[Close]

BLAST of Serine/threonine kinase receptor associated protein vs. Ensembl Celegans
Match: smu-1 (Smu-1 suppressor of mec-8 and unc-52 protein [Source:UniProtKB/Swiss-Prot;Acc:G5EEG7])

HSP 1 Score: 51.9878 bits (123), Expect = 2.214e-7
Identity = 34/111 (30.63%), Postives = 53/111 (47.75%), Query Frame = 3

Query:  351 GAVWSCTLSNDASKAATGAADFTAKVWDCENGKAITSIDHNHI--VRCVDFNETANQLVTATNKFGIEIHDLKSPGKPIMNFNGHTDMIHRTMWLNDDQKIISVSKDKTIR 677
             AV   + S D+   ATG+ D   KVW  E G  +   D  H   V  V F++  + +++  N   + +H +KS GK +    GH+  I    + ++   IIS S D +IR
Sbjct:  265 AAVRCISFSRDSEMLATGSIDGKIKVWKVETGDCLRRFDRAHTKGVCAVRFSKDNSHILSGGNDHVVRVHGMKS-GKCLKEMRGHSSYITDVRYSDEGNHIISCSTDGSIR 374

[Close]

BLAST of Serine/threonine kinase receptor associated protein vs. Ensembl Fly
Match: wmd (gene:FBgn0034876 transcript:FBtr0113112)

HSP 1 Score: 165.622 bits (418), Expect = 8.224e-49
Identity = 81/167 (48.50%), Postives = 111/167 (66.47%), Query Frame = 3

Query:  177 LRQNSIQCSGHTRPVVDLHFSRLNDDKTYYVISASKDSVPMLRFGHTGDWIGSFKGHKGAVWSCTLSNDASKAATGAADFTAKVWDCENGKAITSIDHNHIVRCVDFNETANQLVTATNKFGIEIHDLKSPGKPIMNFNGHTDMIHRTMWLNDDQKIISVSKDKTIR 677
            LRQ  + CSGHTRPVV L FS + D   Y++ISA KD  PMLR G TGDW+G+F+GHKGAVW+ TL+ +A+ AA+GAADFT KVW+   G  I S  H HIV+ V F+  +  +VT +N+  + + +L+ P      + GHT  I R ++   D+ IIS ++DKT+R
Sbjct:    6 LRQIPLTCSGHTRPVVHLDFSDICD-AGYFLISACKDGSPMLRHGDTGDWVGTFEGHKGAVWNATLNRNATLAASGAADFTGKVWNAVTGAEIHSFQHKHIVKSVAFDRDSENIVTGSNEKLVRVFNLEQPEAQPEEYAGHTGAIKRALFCRGDKCIISAAEDKTVR 171

[Close]

BLAST of Serine/threonine kinase receptor associated protein vs. Ensembl Fly
Match: wmd (gene:FBgn0034876 transcript:FBtr0072114)

HSP 1 Score: 165.622 bits (418), Expect = 8.224e-49
Identity = 81/167 (48.50%), Postives = 111/167 (66.47%), Query Frame = 3

Query:  177 LRQNSIQCSGHTRPVVDLHFSRLNDDKTYYVISASKDSVPMLRFGHTGDWIGSFKGHKGAVWSCTLSNDASKAATGAADFTAKVWDCENGKAITSIDHNHIVRCVDFNETANQLVTATNKFGIEIHDLKSPGKPIMNFNGHTDMIHRTMWLNDDQKIISVSKDKTIR 677
            LRQ  + CSGHTRPVV L FS + D   Y++ISA KD  PMLR G TGDW+G+F+GHKGAVW+ TL+ +A+ AA+GAADFT KVW+   G  I S  H HIV+ V F+  +  +VT +N+  + + +L+ P      + GHT  I R ++   D+ IIS ++DKT+R
Sbjct:    6 LRQIPLTCSGHTRPVVHLDFSDICD-AGYFLISACKDGSPMLRHGDTGDWVGTFEGHKGAVWNATLNRNATLAASGAADFTGKVWNAVTGAEIHSFQHKHIVKSVAFDRDSENIVTGSNEKLVRVFNLEQPEAQPEEYAGHTGAIKRALFCRGDKCIISAAEDKTVR 171

[Close]

BLAST of Serine/threonine kinase receptor associated protein vs. Ensembl Fly
Match: CG10459 (gene:FBgn0033440 transcript:FBtr0088468)

HSP 1 Score: 107.457 bits (267), Expect = 8.576e-27
Identity = 59/165 (35.76%), Postives = 91/165 (55.15%), Query Frame = 3

Query:  192 IQCSGHTRPVVDLHFSRLNDDKTYYVISASKDSVPMLRFGHTGDWIGSFKGHKGAVWSCTLSNDASKAATGAADFTAKVWDCENGKAITSIDHNHIVRCVDFNETANQLVTAT--NKFGIEIHDLKSPGK-PIMNFNGHTDMIHRTMWLNDDQKIISVSKDKTIR 677
            + C GH+  VV+L F+R + D  Y++ SA  D V  LR G TGD I   + H  +VWS +LS+DA   A+G AD   +VWD   GK +  + H   V CVD N  A +L+T     +  + + D++   K P+M F GH+  +   ++  ++   +S S D+T+R
Sbjct:    7 VLCPGHSDSVVELSFNR-DYDTGYFLASAGLDGVAALRHGDTGDCITHLRKHTDSVWSVSLSHDAKILASGGADCKVRVWDALLGKQLKKLRHTKTVACVDLNPKATRLLTGCIDQESPLALFDMEQSEKAPLMEFRGHSRGVRDVIFCLEEHCFLSSSYDRTVR 170

[Close]

BLAST of Serine/threonine kinase receptor associated protein vs. Ensembl Fly
Match: eIF3i (gene:FBgn0015834 transcript:FBtr0079053)

HSP 1 Score: 79.337 bits (194), Expect = 1.237e-16
Identity = 49/165 (29.70%), Postives = 79/165 (47.88%), Query Frame = 3

Query:  192 IQCSGHTRPVVDLHFSRLNDDKTYYVISASKDSVPMLRFGHTGDWIGSFKGHKGAVWSCTLSNDASKAATGAADFTAKVWDCENGKAITSIDHNHIVRCVDFNETANQLVTATNK--------FGIEIHDLK---SPGKPIMNFNGHTDMIHRTMWLNDDQKIIS 653
            +   GH R +  + ++R  D     + S SKD  P + +   G+ +G++ GH+GAVW   +  ++ K  TGA D TAK+WD E G  I SI     VR  +F+ + NQ   +T+K        F I++ +     S  +P +        I   +W   D+ II+
Sbjct:    4 LMLQGHERSITQIKYNREGD----LLFSCSKDQKPNVWYSLNGERLGTYDGHQGAVWCLDVDWESRKLITGAGDMTAKIWDVEYGTVIASIPTKSSVRTSNFSFSGNQAAYSTDKAMGQSCELFLIDVRNADSSLSEQEPTLRIPMTESKITSMLWGPLDETIIT 164

[Close]

BLAST of Serine/threonine kinase receptor associated protein vs. Ensembl Fly
Match: wds (gene:FBgn0040066 transcript:FBtr0308566)

HSP 1 Score: 61.2326 bits (147), Expect = 2.280e-10
Identity = 42/160 (26.25%), Postives = 80/160 (50.00%), Query Frame = 3

Query:  201 SGHTRPVVDLHFSRLNDDKTYYVISASKDSVPMLRFGHTGDWIGSFKGHKGAVWSCTLSNDASKAATGAADFTAKVWDCENGKAITSID-HNHIVRCVDFNETANQLVTATNKFGIEIHDLKSPGKPIMNFNGHTDMIHRTMWLNDDQKIISVSKDKTIR 677
            +GHT+ V  + FS   +    ++ S+S D +  +   + G +  +  GHK  +     S+D+    +G+ D T KVW+   GK++ ++  H++ V C +FN  +N +V+ +    + I D+++ GK +     H+D +    +  D   I+S S D   R
Sbjct:   69 AGHTKAVSAVKFSPNGE----WLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDSRLLVSGSDDKTLKVWELSTGKSLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVRT-GKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCR 223

[Close]

BLAST of Serine/threonine kinase receptor associated protein vs. Ensembl Zebrafish
Match: strap (serine/threonine kinase receptor associated protein [Source:ZFIN;Acc:ZDB-GENE-040426-1110])

HSP 1 Score: 158.688 bits (400), Expect = 5.939e-46
Identity = 88/168 (52.38%), Postives = 113/168 (67.26%), Query Frame = 3

Query:  174 ALRQNSIQCSGHTRPVVDLHFSRLNDDKTYYVISASKDSVPMLRFGHTGDWIGSFKGHKGAVWSCTLSNDASKAATGAADFTAKVWDCENGKAITSIDHNHIVRCVDFNETANQLVTATNKFGIEIHDLKSPGKPIMNFNGHTDMIHRTMWLNDDQKIISVSKDKTIR 677
            A+RQ  + CSGHTRPVVDL FS +     Y++ISA KD  PMLR G TGDWIG+F GHKGAVW  TL+ +A+KAAT AADFTAKVWD   G  + ++ H HIV+ V+F + +N L+T  N   + I+DL  P        GHT  I + +W N+DQ+I+S + DKTIR
Sbjct:    2 AMRQTPLTCSGHTRPVVDLAFSGITP-YGYFLISACKDGKPMLRQGDTGDWIGTFLGHKGAVWGATLNTEATKAATAAADFTAKVWDAVTGDEVLTLAHKHIVKSVNFTQDSNYLLTGGNDKVLRIYDLSKPEAEPQEIAGHTSAIKKALWCNNDQQILSAADDKTIR 168

[Close]

BLAST of Serine/threonine kinase receptor associated protein vs. Ensembl Zebrafish
Match: eif3i (eukaryotic translation initiation factor 3, subunit I [Source:NCBI gene;Acc:406263])

HSP 1 Score: 70.8626 bits (172), Expect = 1.445e-13
Identity = 38/131 (29.01%), Postives = 69/131 (52.67%), Query Frame = 3

Query:  192 IQCSGHTRPVVDLHFSRLNDDKTYYVISASKDSVPMLRFGHTGDWIGSFKGHKGAVWSCTLSNDASKAATGAADFTAKVWDCENGKAITSIDHNHIVRCVDFNETANQLVTATNK-FG----IEIHDLKSP 569
            I   GH R +  + ++R  D     + S +KD +  + +   G+ +G++ GH GAVW   +  D     TG+AD + ++WDCE GK +  ++ +  VR   F+ + N ++ +T+K  G    +  +DL+ P
Sbjct:    4 ILLQGHERSITQIKYNREGD----LLFSVAKDPIANVWYSVNGERLGTYNGHTGAVWCVDVDWDTKNVLTGSADNSCRLWDCETGKQLALLETSSAVRTCGFDFSGNIIMFSTDKQMGYQCFLNYYDLRDP 130

[Close]

BLAST of Serine/threonine kinase receptor associated protein vs. Ensembl Zebrafish
Match: nle1 (notchless homolog 1 (Drosophila) [Source:ZFIN;Acc:ZDB-GENE-050522-321])

HSP 1 Score: 66.6254 bits (161), Expect = 5.799e-12
Identity = 50/178 (28.09%), Postives = 87/178 (48.88%), Query Frame = 3

Query:  150 TMEKLNNKAL-RQNSIQCSGHTRPVVDLHFSRLNDDKTYYVISASKDSVPMLRFGHTGDWIGSFKGHKGAVWSCTLSNDASKAATGAADFTAKVWDCENGKAITSI-DHNHIVRCVDFNETANQLVTATNKFGIEIHDLKSPGKPIMNFNGHTDMIHRTMWLNDDQKIISVSKDKTIR 677
            ++E++  KAL R NS++  GH R V        +DD T ++ + ++D  P+ R            GH+  V     S D    A+ + D + K+WD + GK + S+  H   V  V ++  +  LV+ ++   +++ D+K+ GK   +  GH D +    W  D Q++ S  KDK +R
Sbjct:  312 SLEEIKEKALKRYNSVRGEGHERLVSG------SDDFTMFLWNPAEDKKPVARL----------TGHQALVNEVLFSPDTRLIASASFDKSIKIWDGKTGKYLNSLRGHVGPVYQVAWSADSRLLVSGSSDSTLKVWDIKT-GKLNADLPGHADEVFAVDWSPDGQRVASGGKDKCLR 472

[Close]

Query:  150 TMEKLNNKAL-RQNSIQCSGHTRPVVDLHFSRLNDDKTYYVISASKDSVPMLRFGHTGDWIGSFKGHKGAVWSCTLSNDASKAATGAADFTAKVWDCENGKAITSI-DHNHIVRCVDFNETANQLVTATNKFGIEIHDLKSPGKPIMNFNGHTDMIHRTMWLNDDQKIISVSKDKTIR 677
            ++E++  KAL R NS++  GH R V        +DD T ++ + ++D  P+ R            GH+  V     S D    A+ + D + K+WD + GK + S+  H   V  V ++  +  LV+ ++   +++ D+K+ GK   +  GH D +    W  D Q++ S  KDK +R
Sbjct:  312 SLEEIKEKALKRYNSVRGEGHERLVSG------SDDFTMFLWNPAEDKKPVARL----------TGHQALVNEVLFSPDTRLIASASFDKSIKIWDGKTGKYLNSLRGHVGPVYQVAWSADSRLLVSGSSDSTLKVWDIKT-GKLNADLPGHADEVFAVDWSPDGQRVASGGKDKCLR 472

[Close]

Query:  150 TMEKLNNKAL-RQNSIQCSGHTRPVVDLHFSRLNDDKTYYVISASKDSVPMLRFGHTGDWIGSFKGHKGAVWSCTLSNDASKAATGAADFTAKVWDCENGKAITSI-DHNHIVRCVDFNETANQLVTATNKFGIEIHDLKSPGKPIMNFNGHTDMIHRTMWLNDDQKIISVSKDKTIR 677
            ++E++  KAL R NS++  GH R V        +DD T ++ + ++D  P+ R            GH+  V     S D    A+ + D + K+WD + GK + S+  H   V  V ++  +  LV+ ++   +++ D+K+ GK   +  GH D +    W  D Q++ S  KDK +R
Sbjct:  312 SLEEIKEKALKRYNSVRGEGHERLVSG------SDDFTMFLWNPAEDKKPVARL----------TGHQALVNEVLFSPDTRLIASASFDKSIKIWDGKTGKYLNSLRGHVGPVYQVAWSADSRLLVSGSSDSTLKVWDIKT-GKLNADLPGHADEVFAVDWSPDGQRVASGGKDKCLR 472

[Close]

BLAST of Serine/threonine kinase receptor associated protein vs. Ensembl Xenopus
Match: strap (serine/threonine kinase receptor associated protein [Source:NCBI gene;Acc:100145616])

HSP 1 Score: 152.14 bits (383), Expect = 4.797e-44
Identity = 86/167 (51.50%), Postives = 111/167 (66.47%), Query Frame = 3

Query:  177 LRQNSIQCSGHTRPVVDLHFSRLNDDKTYYVISASKDSVPMLRFGHTGDWIGSFKGHKGAVWSCTLSNDASKAATGAADFTAKVWDCENGKAITSIDHNHIVRCVDFNETANQLVTATNKFGIEIHDLKSPGKPIMNFNGHTDMIHRTMWLNDDQKIISVSKDKTIR 677
            +RQ  + CSGHTRPVVDL FS +     +++ISA KD  PMLR G TGDWIG+F GHKGAVW  TL+ DA+KAAT AADFTAKVWD   G  + ++ H HIV+ VDF E +N L+T      + I+D+  P       +GHT  I + +W N+D +I+S S DKT+R
Sbjct:    1 MRQTPLTCSGHTRPVVDLAFSPVTP-YGFFLISACKDGKPMLRQGDTGDWIGTFLGHKGAVWGATLNRDATKAATAAADFTAKVWDAVTGDELITLAHKHIVKSVDFTEDSNNLLTGGQDKVLRIYDMNKPEAEPWEISGHTSAIKKALWYNNDNQILSASDDKTVR 166

[Close]

BLAST of Serine/threonine kinase receptor associated protein vs. Ensembl Xenopus
Match: eif3i (eukaryotic translation initiation factor 3 subunit I [Source:NCBI gene;Acc:548498])

HSP 1 Score: 68.5514 bits (166), Expect = 1.308e-12
Identity = 44/164 (26.83%), Postives = 77/164 (46.95%), Query Frame = 3

Query:  192 IQCSGHTRPVVDLHFSRLNDDKTYYVISASKDSVPMLRFGHTGDWIGSFKGHKGAVWSCTLSNDASKAATGAADFTAKVWDCENGKAITSIDHNHIVRCVDFNETANQLVTATNK-FG----IEIHDLKSP-----GKPIMNFNGHTDMIHRTMWLNDDQKIIS 653
            I   GH R +  + ++R  D     + + +KD V  + +   G+ +G++ GH GAVW   +  D     +G+AD + ++WDCE GK +  ++ N  VR   F+   N ++ +T+K  G    +   DL+ P      +P M        I   +W    + II+
Sbjct:    4 ILLQGHERSITQIKYNRDGD----LLFTVAKDPVVNVWYSVNGERLGTYSGHTGAVWCVDVDWDTRHVLSGSADNSCRLWDCETGKQLALLETNSAVRTCGFDFGGNIIMFSTDKQMGYQCFVSFIDLRDPTQIEDNEPYMKIPCSESKITSAVWGPLGENIIA 163

[Close]

Query:  192 IQCSGHTRPVVDLHFSRLNDDKTYYVISASKDSVPMLRFGHTGDWIGSFKGHKGAVWSCTLSNDASKAATGAADFTAKVWDCENGKAITSIDHNHIVRCVDFNETANQLVTATNK-FG----IEIHDLKSP-----GKPIMNFNGHTDMIHRTMWLNDDQKIIS 653
            I   GH R +  + ++R  D     + + +KD V  + +   G+ +G++ GH GAVW   +  D     +G+AD + ++WDCE GK +  ++ N  VR   F+   N ++ +T+K  G    +   DL+ P      +P M        I   +W    + II+
Sbjct:    4 ILLQGHERSITQIKYNRDGD----LLFTVAKDPVVNVWYSVNGERLGTYSGHTGAVWCVDVDWDTRHVLSGSADNSCRLWDCETGKQLALLETNSAVRTCGFDFGGNIIMFSTDKQMGYQCFVSFIDLRDPTQIEDNEPYMKIPCSESKITSAVWGPLGENIIA 163

[Close]

BLAST of Serine/threonine kinase receptor associated protein vs. Ensembl Xenopus
Match: ppp6c (protein phosphatase 6, catalytic subunit [Source:Xenbase;Acc:XB-GENE-1017127])

HSP 1 Score: 64.3142 bits (155), Expect = 4.469e-11
Identity = 36/110 (32.73%), Postives = 57/110 (51.82%), Query Frame = 3

Query:  354 AVWSCTLSNDASKAATGAADFTAKVWDCENGKAITSIDHNHI--VRCVDFNETANQLVTATNKFGIEIHDLKSPGKPIMNFNGHTDMIHRTMWLNDDQKIISVSKDKTIR 677
            AV     S D    ATGA D   KVW  ++G+ +   +  H   V C+ F++  +Q+++A+    I +H LKS GK +  F GH+  ++   +  D   IIS S D T++
Sbjct:  215 AVLCMCFSRDTEMLATGAQDGKIKVWKIQSGQCLRRFERAHSKGVTCLSFSKDCSQILSASFDQTIRVHGLKS-GKTLKEFRGHSSFVNEATFTQDGHYIISASSDGTVK 323

[Close]

BLAST of Serine/threonine kinase receptor associated protein vs. Ensembl Xenopus
Match: ppp6c (protein phosphatase 6, catalytic subunit [Source:Xenbase;Acc:XB-GENE-1017127])

HSP 1 Score: 64.6994 bits (156), Expect = 4.477e-11
Identity = 36/110 (32.73%), Postives = 57/110 (51.82%), Query Frame = 3

Query:  354 AVWSCTLSNDASKAATGAADFTAKVWDCENGKAITSIDHNHI--VRCVDFNETANQLVTATNKFGIEIHDLKSPGKPIMNFNGHTDMIHRTMWLNDDQKIISVSKDKTIR 677
            AV     S D    ATGA D   KVW  ++G+ +   +  H   V C+ F++  +Q+++A+    I +H LKS GK +  F GH+  ++   +  D   IIS S D T++
Sbjct:  266 AVLCMCFSRDTEMLATGAQDGKIKVWKIQSGQCLRRFERAHSKGVTCLSFSKDCSQILSASFDQTIRVHGLKS-GKTLKEFRGHSSFVNEATFTQDGHYIISASSDGTVK 374

[Close]

BLAST of Serine/threonine kinase receptor associated protein vs. Ensembl Mouse
Match: Strap (serine/threonine kinase receptor associated protein [Source:MGI Symbol;Acc:MGI:1329037])

HSP 1 Score: 149.058 bits (375), Expect = 4.416e-42
Identity = 87/168 (51.79%), Postives = 114/168 (67.86%), Query Frame = 3

Query:  174 ALRQNSIQCSGHTRPVVDLHFSRLNDDKTYYVISASKDSVPMLRFGHTGDWIGSFKGHKGAVWSCTLSNDASKAATGAADFTAKVWDCENGKAITSIDHNHIVRCVDFNETANQLVTATNKFGIEIHDLKSPGKPIMNFNGHTDMIHRTMWLNDDQKIISVSKDKTIR 677
            A+RQ  + CSGHTRPVVDL FS +     Y++ISA KD  PMLR G TGDWIG+F GHKGAVW  TL+ DA+KAAT AADFTAKVWD  +G  + ++ H HIV+ VDF + +N L+T      + I+DL  P       +GHT  I + +W +DD++I+S + DKT+R
Sbjct:    2 AMRQTPLTCSGHTRPVVDLAFSGITP-YGYFLISACKDGKPMLRQGDTGDWIGTFLGHKGAVWGATLNKDATKAATAAADFTAKVWDAVSGDELMTLAHKHIVKTVDFTQDSNYLLTGGQDKLLRIYDLNKPEAEPKEISGHTSGIKKALWCSDDKQILS-ADDKTVR 167

[Close]

BLAST of Serine/threonine kinase receptor associated protein vs. Ensembl Mouse
Match: Eif3i (eukaryotic translation initiation factor 3, subunit I [Source:MGI Symbol;Acc:MGI:1860763])

HSP 1 Score: 68.1662 bits (165), Expect = 1.163e-12
Identity = 42/155 (27.10%), Postives = 72/155 (46.45%), Query Frame = 3

Query:  192 IQCSGHTRPVVDLHFSRLNDDKTYYVISASKDSVPMLRFGHTGDWIGSFKGHKGAVWSCTLSNDASKAATGAADFTAKVWDCENGKAITSIDHNHIVRCVDFNETANQLVTATNK-FG----IEIHDLKSPGK-----PIMNFNGHTDMIHRTMW 626
            I   GH R +  + ++R  D     + + +KD +  + +   G+ +G++ GH GAVW      D     TG+AD + ++WDCE GK +  +  N  VR   F+   N ++ +T+K  G    +   DL+ P +     P M    +   I   +W
Sbjct:    4 ILLQGHERSITQIKYNREGD----LLFTVAKDPIVNVWYSVNGERLGTYMGHTGAVWCVDADWDTKHVLTGSADNSCRLWDCETGKQLALLKTNSAVRTCGFDFGGNIIMFSTDKQMGYQCFVSFFDLRDPSQIDSNEPYMKIPCNDSKITSAVW 154

[Close]

BLAST of Serine/threonine kinase receptor associated protein vs. Ensembl Mouse
Match: Smu1 (smu-1 suppressor of mec-8 and unc-52 homolog (C. elegans) [Source:MGI Symbol;Acc:MGI:1915546])

HSP 1 Score: 65.4698 bits (158), Expect = 1.472e-11
Identity = 37/110 (33.64%), Postives = 58/110 (52.73%), Query Frame = 3

Query:  354 AVWSCTLSNDASKAATGAADFTAKVWDCENGKAITSIDHNHI--VRCVDFNETANQLVTATNKFGIEIHDLKSPGKPIMNFNGHTDMIHRTMWLNDDQKIISVSKDKTIR 677
            AV     S D    ATGA D   KVW  ++G+ +   +  H   V C+ F++ ++Q+++A+    I IH LKS GK +  F GH+  ++   +  D   IIS S D T++
Sbjct:  266 AVLCMCFSRDTEMLATGAQDGKIKVWKIQSGQCLRRFERAHSKGVTCLSFSKDSSQILSASFDQTIRIHGLKS-GKTLKEFRGHSSFVNEATFTQDGHYIISASSDGTVK 374

[Close]

BLAST of Serine/threonine kinase receptor associated protein vs. Ensembl Mouse
Match: Apaf1 (apoptotic peptidase activating factor 1 [Source:MGI Symbol;Acc:MGI:1306796])

HSP 1 Score: 64.3142 bits (155), Expect = 6.179e-11
Identity = 53/179 (29.61%), Postives = 82/179 (45.81%), Query Frame = 3

Query:  153 MEKLNNKALRQNS-IQCSGHTRPVVDLHFSRLNDDKTYYVISASKDSVPMLRFGHTGDWIGSFKGHKGAVWSCTLSNDASKAATGAADFTAKVWDCENGKAITSID-HNHIVRCVDFNETANQLVTAT--NKFGIEIHDLKSPGKPIMNFNGHTDMIHRTMWLNDDQKIISVSKDKTIR 677
            +E +N K ++  S +    HT  V    FS+        + S   D    +    TG+ +   K H+  V  C  S+D S  AT +AD   K+WD   GK + + D H+  V C  F   +N L+ AT  N F +++ DL         F GHT+ ++   +  DD+ + S S D T+R
Sbjct:  595 LEWINKKTIKNLSRLVVRPHTDAVYHACFSQ----DGQRIASCGADKTLQVFKAETGEKLLDIKAHEDEVLCCAFSSDDSYIATCSADKKVKIWDSATGKLVHTYDEHSEQVNCCHFTNKSNHLLLATGSNDFFLKLWDLNQKECRNTMF-GHTNSVNHCRFSPDDELLASCSADGTLR 768

[Close]

Query:  153 MEKLNNKALRQNS-IQCSGHTRPVVDLHFSRLNDDKTYYVISASKDSVPMLRFGHTGDWIGSFKGHKGAVWSCTLSNDASKAATGAADFTAKVWDCENGKAITSID-HNHIVRCVDFNETANQLVTAT--NKFGIEIHDLKSPGKPIMNFNGHTDMIHRTMWLNDDQKIISVSKDKTIR 677
            +E +N K ++  S +    HT  V    FS+        + S   D    +    TG+ +   K H+  V  C  S+D S  AT +AD   K+WD   GK + + D H+  V C  F   +N L+ AT  N F +++ DL         F GHT+ ++   +  DD+ + S S D T+R
Sbjct:  595 LEWINKKTIKNLSRLVVRPHTDAVYHACFSQ----DGQRIASCGADKTLQVFKAETGEKLLDIKAHEDEVLCCAFSSDDSYIATCSADKKVKIWDSATGKLVHTYDEHSEQVNCCHFTNKSNHLLLATGSNDFFLKLWDLNQKECRNTMF-GHTNSVNHCRFSPDDELLASCSADGTLR 768

[Close]

BLAST of Serine/threonine kinase receptor associated protein vs. UniProt/SwissProt
Match: sp|Q54LT8|STRAP_DICDI (Serine-threonine kinase receptor-associated protein OS=Dictyostelium discoideum OX=44689 GN=strap PE=3 SV=1)

HSP 1 Score: 148.673 bits (374), Expect = 1.159e-41
Identity = 75/168 (44.64%), Postives = 109/168 (64.88%), Query Frame = 3

Query:  177 LRQNSIQCSGHTRPVVDLHFSRLNDDKTYYVISASKDSVPMLRFGHTGDWIGSFKGHKGAVWSCTLSNDASKAATGAADFTAKVWDCENGKAITSIDHNHIVRCVDFNETANQLVTATNKFGIEIHDLKSPGKPIMNFNGHTDMIHRTMW-LNDDQKIISVSKDKTIR 677
            +RQ  I CSGH+RPV DL FS  N D ++ ++SA  D  PMLR G  GDWIG+F+GHKGAVWS   ++ AS+A T +AD+T K+WD  NG  I SI+H  IV+  DF+   +++VT  ++  + I DL+ P  P++  +GHT+ I    W +++D  ++S   D+ IR
Sbjct:    1 MRQPLI-CSGHSRPVSDLSFSNENSDGSF-IVSACLDGSPMLRNGENGDWIGTFEGHKGAVWSSRFNSTASQALTASADYTVKLWDTLNGSEILSIEHQSIVKTADFSNNNSRVVTGGSEKILRIFDLERPNDPLLQISGHTNTIKTATWSVHNDDIVLSGGLDEVIR 166

[Close]

BLAST of Serine/threonine kinase receptor associated protein vs. UniProt/SwissProt
Match: sp|Q9Z1Z2|STRAP_MOUSE (Serine-threonine kinase receptor-associated protein OS=Mus musculus OX=10090 GN=Strap PE=1 SV=2)

HSP 1 Score: 149.058 bits (375), Expect = 3.089e-41
Identity = 87/168 (51.79%), Postives = 114/168 (67.86%), Query Frame = 3

Query:  174 ALRQNSIQCSGHTRPVVDLHFSRLNDDKTYYVISASKDSVPMLRFGHTGDWIGSFKGHKGAVWSCTLSNDASKAATGAADFTAKVWDCENGKAITSIDHNHIVRCVDFNETANQLVTATNKFGIEIHDLKSPGKPIMNFNGHTDMIHRTMWLNDDQKIISVSKDKTIR 677
            A+RQ  + CSGHTRPVVDL FS +     Y++ISA KD  PMLR G TGDWIG+F GHKGAVW  TL+ DA+KAAT AADFTAKVWD  +G  + ++ H HIV+ VDF + +N L+T      + I+DL  P       +GHT  I + +W +DD++I+S + DKT+R
Sbjct:    2 AMRQTPLTCSGHTRPVVDLAFSGITP-YGYFLISACKDGKPMLRQGDTGDWIGTFLGHKGAVWGATLNKDATKAATAAADFTAKVWDAVSGDELMTLAHKHIVKTVDFTQDSNYLLTGGQDKLLRIYDLNKPEAEPKEISGHTSGIKKALWCSDDKQILS-ADDKTVR 167

[Close]

BLAST of Serine/threonine kinase receptor associated protein vs. UniProt/SwissProt
Match: sp|Q5XIG8|STRAP_RAT (Serine-threonine kinase receptor-associated protein OS=Rattus norvegicus OX=10116 GN=Strap PE=1 SV=1)

HSP 1 Score: 147.517 bits (371), Expect = 1.084e-40
Identity = 86/168 (51.19%), Postives = 114/168 (67.86%), Query Frame = 3

Query:  174 ALRQNSIQCSGHTRPVVDLHFSRLNDDKTYYVISASKDSVPMLRFGHTGDWIGSFKGHKGAVWSCTLSNDASKAATGAADFTAKVWDCENGKAITSIDHNHIVRCVDFNETANQLVTATNKFGIEIHDLKSPGKPIMNFNGHTDMIHRTMWLNDDQKIISVSKDKTIR 677
            A+RQ  + CSGHTRPVVDL FS +     Y++ISA KD  PMLR G TGDWIG+F GHKGAVW  TL+ DA+KAAT AADFTAKVWD  +G  + ++ H HIV+ VDF + +N L+T      + I+DL  P       +GHT  I + +W ++D++I+S + DKT+R
Sbjct:    2 AMRQTPLTCSGHTRPVVDLAFSGITP-YGYFLISACKDGKPMLRQGDTGDWIGTFLGHKGAVWGATLNKDATKAATAAADFTAKVWDAVSGDELMTLAHKHIVKTVDFTQDSNYLLTGGQDKLLRIYDLNKPEAEPKEISGHTSGIKKALWCSEDKQILS-ADDKTVR 167

[Close]

BLAST of Serine/threonine kinase receptor associated protein vs. UniProt/SwissProt
Match: sp|Q5E959|STRAP_BOVIN (Serine-threonine kinase receptor-associated protein OS=Bos taurus OX=9913 GN=STRAP PE=2 SV=1)

HSP 1 Score: 147.517 bits (371), Expect = 1.192e-40
Identity = 86/168 (51.19%), Postives = 114/168 (67.86%), Query Frame = 3

Query:  174 ALRQNSIQCSGHTRPVVDLHFSRLNDDKTYYVISASKDSVPMLRFGHTGDWIGSFKGHKGAVWSCTLSNDASKAATGAADFTAKVWDCENGKAITSIDHNHIVRCVDFNETANQLVTATNKFGIEIHDLKSPGKPIMNFNGHTDMIHRTMWLNDDQKIISVSKDKTIR 677
            A+RQ  + CSGHTRPVVDL FS +     Y++ISA KD  PMLR G TGDWIG+F GHKGAVW  TL+ DA+KAAT AADFTAKVWD  +G  + ++ H HIV+ VDF + +N L+T      + I+DL  P       +GHT  I + +W ++D++I+S + DKT+R
Sbjct:    2 AMRQTPLTCSGHTRPVVDLAFSGITP-YGYFLISACKDGKPMLRQGDTGDWIGTFLGHKGAVWGATLNKDATKAATAAADFTAKVWDAVSGDELMTLAHKHIVKTVDFTQDSNYLLTGGQDKLLRIYDLNKPEAEPKEISGHTSGIKKALWCSEDKQILS-ADDKTVR 167

[Close]

BLAST of Serine/threonine kinase receptor associated protein vs. UniProt/SwissProt
Match: sp|Q9Y3F4|STRAP_HUMAN (Serine-threonine kinase receptor-associated protein OS=Homo sapiens OX=9606 GN=STRAP PE=1 SV=1)

HSP 1 Score: 147.517 bits (371), Expect = 1.411e-40
Identity = 86/168 (51.19%), Postives = 114/168 (67.86%), Query Frame = 3

Query:  174 ALRQNSIQCSGHTRPVVDLHFSRLNDDKTYYVISASKDSVPMLRFGHTGDWIGSFKGHKGAVWSCTLSNDASKAATGAADFTAKVWDCENGKAITSIDHNHIVRCVDFNETANQLVTATNKFGIEIHDLKSPGKPIMNFNGHTDMIHRTMWLNDDQKIISVSKDKTIR 677
            A+RQ  + CSGHTRPVVDL FS +     Y++ISA KD  PMLR G TGDWIG+F GHKGAVW  TL+ DA+KAAT AADFTAKVWD  +G  + ++ H HIV+ VDF + +N L+T      + I+DL  P       +GHT  I + +W ++D++I+S + DKT+R
Sbjct:    2 AMRQTPLTCSGHTRPVVDLAFSGITP-YGYFLISACKDGKPMLRQGDTGDWIGTFLGHKGAVWGATLNKDATKAATAAADFTAKVWDAVSGDELMTLAHKHIVKTVDFTQDSNYLLTGGQDKLLRIYDLNKPEAEPKEISGHTSGIKKALWCSEDKQILS-ADDKTVR 167

[Close]

BLAST of Serine/threonine kinase receptor associated protein vs. TrEMBL
Match: T1FM24 (WD_REPEATS_REGION domain-containing protein OS=Helobdella robusta OX=6412 GN=20209873 PE=4 SV=1)

HSP 1 Score: 193.741 bits (491), Expect = 3.203e-56
Identity = 94/168 (55.95%), Postives = 124/168 (73.81%), Query Frame = 3

Query:  174 ALRQNSIQCSGHTRPVVDLHFSRLNDDKTYYVISASKDSVPMLRFGHTGDWIGSFKGHKGAVWSCTLSNDASKAATGAADFTAKVWDCENGKAITSIDHNHIVRCVDFNETANQLVTATNKFGIEIHDLKSPGKPIMNFNGHTDMIHRTMWLNDDQKIISVSKDKTIR 677
            ++RQN + CSGHTRPVV L FSR+  D  Y+VISASKD+ PMLR G TGDWIG+F+GHKGAVW+ TL+ +ASKAATG+ADFTAKVW+   G+ + S  H HIV+CVDF+  +N L+T +N+  + I+DL  P +     NGHT  +   +WL DD+ IIS ++DKTI+
Sbjct:    3 SMRQNPLTCSGHTRPVVHLSFSRITPDG-YFVISASKDAKPMLRQGETGDWIGTFEGHKGAVWAATLNYEASKAATGSADFTAKVWNAVTGEEVQSFAHKHIVKCVDFSPDSNYLLTGSNEKLLRIYDLNKPSESPEVINGHTSNLKCCLWL-DDRTIISAAEDKTIK 168

[Close]

BLAST of Serine/threonine kinase receptor associated protein vs. TrEMBL
Match: T1K495 (WD_REPEATS_REGION domain-containing protein OS=Tetranychus urticae OX=32264 GN=107360417 PE=4 SV=1)

HSP 1 Score: 187.578 bits (475), Expect = 4.671e-54
Identity = 93/168 (55.36%), Postives = 120/168 (71.43%), Query Frame = 3

Query:  174 ALRQNSIQCSGHTRPVVDLHFSRLNDDKTYYVISASKDSVPMLRFGHTGDWIGSFKGHKGAVWSCTLSNDASKAATGAADFTAKVWDCENGKAITSIDHNHIVRCVDFNETANQLVTATNKFGIEIHDLKSPGKPIMNFNGHTDMIHRTMWLNDDQKIISVSKDKTIR 677
            AL+Q+++ C+GHTRPVV L+FS + D K YY+ISA KD  PMLR G TGDWIG+F+GHKGAVW   L+ DASKAATGAADF+AK+WD  NG  + S+ H HIV+ V F+  ++QLVT +N+  + I DL       +  NGHT  I   ++LNDD+ +IS S DKTIR
Sbjct:    2 ALKQHNLTCTGHTRPVVFLNFSGITDGK-YYLISACKDGKPMLRQGETGDWIGTFEGHKGAVWGAALNVDASKAATGAADFSAKLWDAINGSELASLPHRHIVKSVSFSTDSSQLVTGSNEKLMRIFDLNRLDAEPLKINGHTSSIRHALFLNDDRWLISASDDKTIR 168

[Close]

BLAST of Serine/threonine kinase receptor associated protein vs. TrEMBL
Match: T1K499 (WD_REPEATS_REGION domain-containing protein OS=Tetranychus urticae OX=32264 PE=4 SV=1)

HSP 1 Score: 187.193 bits (474), Expect = 1.612e-53
Identity = 93/168 (55.36%), Postives = 120/168 (71.43%), Query Frame = 3

Query:  174 ALRQNSIQCSGHTRPVVDLHFSRLNDDKTYYVISASKDSVPMLRFGHTGDWIGSFKGHKGAVWSCTLSNDASKAATGAADFTAKVWDCENGKAITSIDHNHIVRCVDFNETANQLVTATNKFGIEIHDLKSPGKPIMNFNGHTDMIHRTMWLNDDQKIISVSKDKTIR 677
            AL+Q+++ C+GHTRPVV L+FS + D K YY+ISA KD  PMLR G TGDWIG+F+GHKGAVW   L+ DASKAATGAADF+AK+WD  NG  + S+ H HIV+ V F+  ++QLVT +N+  + I DL       +  NGHT  I   ++LNDD+ +IS S DKTIR
Sbjct:    2 ALKQHNLTCTGHTRPVVFLNFSGITDGK-YYLISACKDGKPMLRQGETGDWIGTFEGHKGAVWGAALNVDASKAATGAADFSAKLWDAINGSELASLPHRHIVKSVSFSTDSSQLVTGSNEKLMRIFDLNRLDAEPLKINGHTSSIRHALFLNDDRWLISASDDKTIR 168

[Close]

BLAST of Serine/threonine kinase receptor associated protein vs. TrEMBL
Match: A0A023FLZ8 (Putative serine/threonine kinase receptor-associated protein (Fragment) OS=Amblyomma cajennense OX=34607 PE=2 SV=1)

HSP 1 Score: 187.193 bits (474), Expect = 1.992e-53
Identity = 92/170 (54.12%), Postives = 117/170 (68.82%), Query Frame = 3

Query:  171 KALRQNSIQCSGHTRPVVDLHFSRLNDDKTYYVISASKDSVPMLRFGHTGDWIGSFKGHKGAVWSCTLSNDASKAATGAADFTAKVWDCENGKAITSIDHNHIVRCVDFNETANQLVTATNKFGIEIHDL-KSPGKPIMNFNGHTDMIHRTMWLNDDQKIISVSKDKTIR 677
            + LRQ  + CSGHTRPVVDL FS+L+   TYY+ISA KD  PMLR G TGDWIG+F GHKGAVW   L+ DAS AATGAADFTAK+W+   G+ + +  H HIVRCVDF+    +L+T +N   + I D+ K    P M   GHT  I + ++L DD++I+S S DKT+R
Sbjct:    1 RRLRQTPLTCSGHTRPVVDLCFSKLSSTGTYYLISACKDGKPMLRQGDTGDWIGTFVGHKGAVWGVALNKDASVAATGAADFTAKLWNAVAGEELHTFAHPHIVRCVDFDSEGVRLLTGSNDKTLRIFDVNKEDAAPTM-MKGHTSAIKKVLFLQDDKRIVSASDDKTVR 169

[Close]

BLAST of Serine/threonine kinase receptor associated protein vs. TrEMBL
Match: A0A0C9S2N0 (Putative serine/threonine kinase receptor-associated protein OS=Amblyomma americanum OX=6943 PE=2 SV=1)

HSP 1 Score: 186.422 bits (472), Expect = 3.745e-53
Identity = 91/169 (53.85%), Postives = 116/169 (68.64%), Query Frame = 3

Query:  174 ALRQNSIQCSGHTRPVVDLHFSRLNDDKTYYVISASKDSVPMLRFGHTGDWIGSFKGHKGAVWSCTLSNDASKAATGAADFTAKVWDCENGKAITSIDHNHIVRCVDFNETANQLVTATNKFGIEIHDL-KSPGKPIMNFNGHTDMIHRTMWLNDDQKIISVSKDKTIR 677
             LRQ  + CSGHTRPVVDL FS+L+   TYY+ISA KD  PMLR G TGDWIG+F GHKGAVW   L+ DAS AATGAADFTAK+W+   G+ + +  H HIVRCVDF+    +L+T +N   + I D+ K    P M   GHT  I + ++L DD++I+S S DK++R
Sbjct:    3 GLRQTPLTCSGHTRPVVDLCFSKLSSTGTYYLISACKDGKPMLRQGDTGDWIGTFVGHKGAVWGVALNKDASVAATGAADFTAKLWNAVAGEELHTFSHPHIVRCVDFDSEGVRLLTGSNDKTLRIFDVNKEDAAPTM-LKGHTSAIKKVLFLQDDKRIVSASDDKSVR 170

[Close]

BLAST of Serine/threonine kinase receptor associated protein vs. Ensembl Cavefish
Match: strap (serine/threonine kinase receptor associated protein [Source:NCBI gene;Acc:111193019])

HSP 1 Score: 166.392 bits (420), Expect = 5.508e-49
Identity = 85/168 (50.60%), Postives = 114/168 (67.86%), Query Frame = 3

Query:  174 ALRQNSIQCSGHTRPVVDLHFSRLNDDKTYYVISASKDSVPMLRFGHTGDWIGSFKGHKGAVWSCTLSNDASKAATGAADFTAKVWDCENGKAITSIDHNHIVRCVDFNETANQLVTATNKFGIEIHDLKSPGKPIMNFNGHTDMIHRTMWLNDDQKIISVSKDKTIR 677
            A+RQ  + CSGHTRPVVDL FS +     Y++ISA KD  PMLR G TGDWIG+F GHKGAVW  TL+ +A+KAAT AADF+AKVWD   G  + ++ H HIV+ V+F + +N L+T  N   + I+DL  P       +GHT  + + +W N+DQ+I+S + D+TIR
Sbjct:    2 AMRQTPLTCSGHTRPVVDLAFSGITP-YGYFLISACKDGKPMLRQGDTGDWIGTFLGHKGAVWGATLNKEATKAATAAADFSAKVWDAVTGDEVLTLAHKHIVKSVNFTQDSNCLLTGGNDKLLRIYDLSKPEAEPQEISGHTSAVKKALWCNNDQQILSAADDRTIR 168

[Close]

BLAST of Serine/threonine kinase receptor associated protein vs. Ensembl Cavefish
Match: eif3i (eukaryotic translation initiation factor 3 subunit I [Source:NCBI gene;Acc:103045556])

HSP 1 Score: 71.633 bits (174), Expect = 6.229e-14
Identity = 39/131 (29.77%), Postives = 68/131 (51.91%), Query Frame = 3

Query:  192 IQCSGHTRPVVDLHFSRLNDDKTYYVISASKDSVPMLRFGHTGDWIGSFKGHKGAVWSCTLSNDASKAATGAADFTAKVWDCENGKAITSIDHNHIVRCVDFNETANQLVTATNK-FGIEIH----DLKSP 569
            I   GH R +  + ++R  D     + S +KD    + +   G+ +G++ GH GAVW   +  D     TG+AD + ++WDCE GK +  ++ N  VR   F+ + N ++ +T+K  G + +    DL+ P
Sbjct:    4 ILLQGHERSLTQIKYNREGD----LLFSVAKDQFANVWYSVNGERLGTYNGHSGAVWCVDVDWDTKNVLTGSADNSCRLWDCETGKQLAMLETNSAVRTCGFDFSGNIIMFSTDKQMGYQCYLNYFDLRDP 130

[Close]

BLAST of Serine/threonine kinase receptor associated protein vs. Ensembl Cavefish
Match: smu1a (SMU1 DNA replication regulator and spliceosomal factor a [Source:NCBI gene;Acc:393168])

HSP 1 Score: 66.2402 bits (160), Expect = 6.348e-12
Identity = 38/110 (34.55%), Postives = 58/110 (52.73%), Query Frame = 3

Query:  354 AVWSCTLSNDASKAATGAADFTAKVWDCENGKAITSIDHNHI--VRCVDFNETANQLVTATNKFGIEIHDLKSPGKPIMNFNGHTDMIHRTMWLNDDQKIISVSKDKTIR 677
            AV     S D    ATGA D   KVW  ++G+ +   +  H   V CV F++ ++QL++A+    I +H LKS GK +  F GH+  ++   +  D   IIS S D T++
Sbjct:  215 AVLCMCFSRDTEMLATGAQDGKIKVWKIQSGQCLRRFERAHSKGVTCVSFSKDSSQLLSASFDQTIRVHGLKS-GKSLKEFRGHSSFVNEATFTPDGHHIISASSDGTVK 323

[Close]

BLAST of Serine/threonine kinase receptor associated protein vs. Ensembl Cavefish
Match: snrnp40 (small nuclear ribonucleoprotein U5 subunit 40 [Source:NCBI gene;Acc:103032740])

HSP 1 Score: 62.3882 bits (150), Expect = 1.025e-10
Identity = 46/166 (27.71%), Postives = 82/166 (49.40%), Query Frame = 3

Query:  183 QNSIQCSGHTRPVVDLHFSRLNDDKTYYVISASKDSVPMLRFGHTGDWIGSFKGHKGAVWSCTLSNDASK-AATGAADFTAKVWDCENGKAITSIDHNHIVRCVDFNETANQLVTATNKFGIEIHDLKSPGKPIMNFNGHTDMIHRTMWLNDDQKIISVSKDKTIR 677
            +N     GH+  V++LH+   N D +  + SAS D    +    TG+ +   KGH   V SC  +    + A TG+ D T K+WD     ++ +  + + V  V FN+T++Q+++      I++ DL+   K I +  GH D +      ++   ++S S D ++R
Sbjct:   90 ENFATLKGHSGAVMELHY---NTDGSL-LYSASTDKTVCVWDSETGERVKRLKGHTSFVNSCFPARRGPQLACTGSDDGTVKLWDIRKKASVHTFQNTYQVLSVTFNDTSDQIISGGIDNDIKVWDLRQ-NKLIYSMQGHGDSVTGLSLSSEGSYLLSNSMDNSVR 250

[Close]

BLAST of Serine/threonine kinase receptor associated protein vs. Ensembl Cavefish
Match: wdr5 (WD repeat domain 5 [Source:NCBI gene;Acc:103033424])

HSP 1 Score: 62.003 bits (149), Expect = 1.213e-10
Identity = 42/160 (26.25%), Postives = 80/160 (50.00%), Query Frame = 3

Query:  201 SGHTRPVVDLHFSRLNDDKTYYVISASKDSVPMLRFGHTGDWIGSFKGHKGAVWSCTLSNDASKAATGAADFTAKVWDCENGKAITSID-HNHIVRCVDFNETANQLVTATNKFGIEIHDLKSPGKPIMNFNGHTDMIHRTMWLNDDQKIISVSKDKTIR 677
            +GHT+ V  + FS   +    ++ S+S D +  +   + G +  +  GHK  +     S+D++   + + D T K+WD  +GK + ++  H++ V C +FN  +N +V+ +    + I D+K+ GK +     H+D +    +  D   I+S S D   R
Sbjct:   42 AGHTKAVSSVKFSPSGE----WLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDSNLLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKT-GKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCR 196

[Close]

BLAST of Serine/threonine kinase receptor associated protein vs. Ensembl Sea Lamprey
Match: strap (serine/threonine kinase receptor associated protein [Source:ZFIN;Acc:ZDB-GENE-040426-1110])

HSP 1 Score: 143.665 bits (361), Expect = 5.862e-41
Identity = 88/168 (52.38%), Postives = 109/168 (64.88%), Query Frame = 3

Query:  174 ALRQNSIQCSGHTRPVVDLHFSRLNDDKTYYVISASKDSVPMLRFGHTGDWIGSFKGHKGAVWSCTLSNDASKAATGAADFTAKVWDCENGKAITSIDHNHIVRCVDFNETANQLVTATNKFGIEIHDLKSPGKPIMNFNGHTDMIHRTMWLNDDQKIISVSKDKTIR 677
            ALRQ  + CSGHTRPVVDL FS +     Y++ISA KD  PMLR G TGDW+G+F GHKGAVW  TL+ DA+KAAT AADFTAKVWD  +G  + S  H HIV+ VDF E +  L+T      + I+DL+         +GHT  + R  W   ++ IISV+ DKTIR
Sbjct:    2 ALRQTPLTCSGHTRPVVDLAFSTITP-YGYFMISACKDGKPMLRQGDTGDWVGTFLGHKGAVWGATLNRDATKAATAAADFTAKVWDAVSGDEVVSFTHKHIVKTVDFTEDSVHLLTGGQDKVLRIYDLEKTDAEPQLLSGHTSGVRRA-WCTGEKLIISVADDKTIR 167

[Close]

BLAST of Serine/threonine kinase receptor associated protein vs. Ensembl Sea Lamprey
Match: pafah1b1b (platelet-activating factor acetylhydrolase 1b, regulatory subunit 1b [Source:NCBI gene;Acc:394247])

HSP 1 Score: 59.3066 bits (142), Expect = 1.901e-10
Identity = 43/160 (26.88%), Postives = 79/160 (49.38%), Query Frame = 3

Query:  201 SGHTRPVVDLHFSRLNDDKTYYVISASKDSVPMLRFGHTGDWIGSFKGHKGAVWSCTLSNDASKAATGAADFTAKVWDCENGKAITSI-DHNHIVRCVDFNETANQLVTATNKFGIEIHDLKSPGKPIMNFNGHTDMIHRTMWLNDDQKIISVSKDKTIR 677
            SGH  PV  + F  +       ++SAS+D+   +    TGD+  + KGH  +V   +        A+ +AD T K+WD ++ + + ++  H+H V  V F    + LV+A+    +++ ++++ G  +  F GH + +       D   I S S D+T+R
Sbjct:   44 SGHRSPVTRVIFHPVFS----VIVSASEDATIKVWDYETGDFERTLKGHTDSVQDISFDLSGKMLASCSADMTVKLWDFQSFECLRTMHGHDHNVSSVAFMPNGDHLVSASRDKTMKMWEVQT-GYCVKTFTGHREWVRMVRPNQDGSLIASCSNDQTVR 198

[Close]

BLAST of Serine/threonine kinase receptor associated protein vs. Ensembl Sea Lamprey
Match: snrnp40 (small nuclear ribonucleoprotein 40 (U5) [Source:ZFIN;Acc:ZDB-GENE-040426-978])

HSP 1 Score: 56.9954 bits (136), Expect = 1.210e-9
Identity = 44/165 (26.67%), Postives = 76/165 (46.06%), Query Frame = 3

Query:  186 NSIQCSGHTRPVVDLHFSRLNDDKTYYVISASKDSVPMLRFGHTGDWIGSFKGHKGAVWSCTLSNDASK-AATGAADFTAKVWDCENGKAITSIDHNHIVRCVDFNETANQLVTATNKFGIEIHDLKSPGKPIMNFNGHTDMIHRTMWLNDDQKIISVSKDKTIR 677
            N     GHT  ++D+H+S   D  T  + ++S D    L    TG+ I   KGH   V +C  +    +   T + D T K+WD     ++ S  + +    V FN+T++Q+++      I++ DL+   K I    GH D +       D   ++S + D ++R
Sbjct:   92 NYAHLKGHTGAILDIHYS--TDGST--IFTSSTDKTVGLWDSETGERIKRLKGHTSFVNACFPARRGPQMVCTASDDGTVKLWDTRKKGSVHSFQNTYQCLSVTFNDTSDQILSGGIDNVIKVWDLRQ-NKLIYTMKGHNDSVTGLSLSPDGSYLLSNAMDNSVR 251

[Close]

BLAST of Serine/threonine kinase receptor associated protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000004902.1 (pep scaffold:Pmarinus_7.0:GL478254:5937:33805:1 gene:ENSPMAG00000004437.1 transcript:ENSPMAT00000004902.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 50.8322 bits (120), Expect = 2.033e-7
Identity = 41/179 (22.91%), Postives = 81/179 (45.25%), Query Frame = 3

Query:  153 MEKLNNKALRQNSIQCS----GHTRPVVDLHFSRLNDDKTYYVISASKDSVPMLRFGHTGDWIGSFKGHKGAVWSCTLSNDASKAATGAADFTAKVWDCENGKAITSID-HNHIVRCVDFNETANQLVTATNKFGIEIHDLKSPGKPIMNFNGHTDMIHRTMWLNDDQKIISVSKDKTI 674
            ++K  + A+R  S++ S     H  PV  +        +   +++AS D +  +     GD I + +GH   +  C  +   +  ATG  D T KVWD   G  + +++ H H V    ++   + + +++     ++ D+ S  +      GHTD ++   +L     +++ S DKT+
Sbjct:  312 VQKQPSDAMRSGSLRISQTLKAHEMPVSSMALH----PRKEIIVTASDDQLWKMWSIPNGDIIMTGQGHTDWIGDCDFNPTGTNLATGGGDSTVKVWDFSQGACVLTLEGHGHAVWGCSWHSCGDFIASSSMDNSSKVWDVNSE-RCRQTLRGHTDSVNSVEFLPYSSTLLTSSADKTL 485

[Close]

BLAST of Serine/threonine kinase receptor associated protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000008862.1 (pep scaffold:Pmarinus_7.0:GL476579:86637:114999:1 gene:ENSPMAG00000008000.1 transcript:ENSPMAT00000008862.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 49.6766 bits (117), Expect = 4.026e-7
Identity = 33/138 (23.91%), Postives = 69/138 (50.00%), Query Frame = 3

Query:  267 VISASKDSVPMLRFGHTGDWIGSFKGHKGAVWSCTLSNDASKAATGAADFTAKVWDCENGKAI-TSIDHNHIVRCVDFNETANQLVTATNKFGIEIHDLKSPGKPIMNFNGHTDMIHRTMWLNDDQKIISVSKDKTIR 677
            ++S S D+   +    TG  + +  GH G VWS  +  +     +G+ D T KVW+ + G+ + T   H   VRC+  +   N++V+ +    + + D+++ G+ +    GH   +    +  D ++++S + D T++
Sbjct:  247 IVSGSDDNTLKVWSAVTGKCLRTLVGHTGGVWSSQMRGNI--IVSGSTDRTLKVWNADTGQCVHTLYGHTSTVRCMHLH--GNRVVSGSRDATLRVWDIET-GQCLHVLAGHVAAVRCVQY--DGRRVVSGAYDYTVK 377

[Close]

BLAST of Serine/threonine kinase receptor associated protein vs. Ensembl Yeast
Match: TIF34 (eIF3i subunit of the eukaryotic translation initiation factor 3 (eIF3); subunit of the core complex of eIF3; essential for translation; stimulates rate of ribosomal scanning during translation reinitiation; eIF3 is also involved in programmed stop codon readthrough [Source:SGD;Acc:S000004754])

HSP 1 Score: 63.929 bits (154), Expect = 4.360e-12
Identity = 34/128 (26.56%), Postives = 64/128 (50.00%), Query Frame = 3

Query:  189 SIQCSGHTRPVVDLHFSRLNDDKTYYVISASKDSVPMLRFGHTGDWIGSFKGHKGAVWSCTLSNDASKAATGAADFTAKVWDCENGKAITSIDHNHIVRCVDFNETANQLVTATNKFGIEIHDLKSPG 572
            +I+ +GH RP+  + +++  D     + S SKDS   + +   G+ +G+  GH G +WS  +        TG+AD++ K+WD  NG+ + +      V+ V+F+   N  +   +        +K+PG
Sbjct:    3 AIKLTGHERPLTQVKYNKEGD----LLFSCSKDSSASVWYSLNGERLGTLDGHTGTIWSIDVDCFTKYCVTGSADYSIKLWDVSNGQCVATWKSPVPVKRVEFSPCGNYFLAILDNV------MKNPG 120

[Close]

BLAST of Serine/threonine kinase receptor associated protein vs. Ensembl Yeast
Match: ASC1 (G-protein beta subunit and guanine dissociation inhibitor for Gpa2p; ortholog of RACK1 that inhibits translation; core component of the small (40S) ribosomal subunit; required to prevent frameshifting at ribosomes stalled at repeated CGA codons; regulates P-body formation induced by replication stress; represses Gcn4p in the absence of amino acid starvation [Source:SGD;Acc:S000004722])

HSP 1 Score: 51.2174 bits (121), Expect = 5.802e-8
Identity = 40/150 (26.67%), Postives = 73/150 (48.67%), Query Frame = 3

Query:  267 VISASKDSVPMLRFGHTGD------WIGSFKGHKGAVWSCTLSNDASKAATGAADFTAKVWDCENGKAITS-IDHNHIVRCVDFNETANQLVTATNKFGIEIHDLKSPGKPIMNFNGHTDMIHRTMWL------NDDQKIISVSKDKTIR 677
            ++SAS+D   ++ +  TGD       + SFKGH   V  CTL+ D + A + + D T ++WD   G+     + H   V  VD ++ A+ +++ +    I++  +K  G+ +    GH D + +   +      +D   IIS   DK ++
Sbjct:   33 LLSASRDKT-LISWKLTGDDQKFGVPVRSFKGHSHIVQDCTLTADGAYALSASWDKTLRLWDVATGETYQRFVGHKSDVMSVDIDKKASMIISGSRDKTIKVWTIK--GQCLATLLGHNDWVSQVRVVPNEKADDDSVTIISAGNDKMVK 179

[Close]

BLAST of Serine/threonine kinase receptor associated protein vs. Ensembl Yeast
Match: RSA4 (WD-repeat protein involved in ribosome biogenesis; may interact with ribosomes; required for maturation and efficient intra-nuclear transport or pre-60S ribosomal subunits, localizes to the nucleolus [Source:SGD;Acc:S000000668])

HSP 1 Score: 45.0542 bits (105), Expect = 8.951e-6
Identity = 35/145 (24.14%), Postives = 67/145 (46.21%), Query Frame = 3

Query:  246 NDDKTYYVISASKDSVPMLRFGHTGDWIGSFKGHKGAVWSCTLSNDASKAATGAADFTAKVWDCENGKAITSI-DHNHIVRCVDFNETANQLVTATNKFGIEIHDLKSPGKPIMNFNGHTDMIHRTMWLNDDQKIISVSKDKTIR 677
            +DD T ++ +  K + P+ R            GH+  V     S D     + + D + K+WD  +GK I++   H   V  V ++     LV+ +    +++ D+++  K  ++  GH D ++   W  D +++ S  KDK +R
Sbjct:  378 SDDYTMFLWNPLKSTKPIARM----------TGHQKLVNHVAFSPDGRYIVSASFDNSIKLWDGRDGKFISTFRGHVASVYQVAWSSDCRLLVSCSKDTTLKVWDVRT-RKLSVDLPGHKDEVYTVDWSVDGKRVCSGGKDKMVR 511

[Close]

BLAST of Serine/threonine kinase receptor associated protein vs. Ensembl Nematostella
Match: EDO27706 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T8I0])

HSP 1 Score: 82.4185 bits (202), Expect = 2.901e-19
Identity = 53/166 (31.93%), Postives = 77/166 (46.39%), Query Frame = 3

Query:  180 RQNSIQCSGHTRPVVDLHFSRLNDDKTYYVISASKDSVPMLRFGHTGDWIGSFKGHKGAVWSCTLSNDASKAATGAADFTAKVWDCENGKAITSIDHNHIVRCVDFNETANQLVTATNKFGIEIHDLKSPGKPIMNFNGHTDMIHRTMWLNDDQKIISVSKDKTIR 677
            RQ  + CSGHTRPVVDLHFS +     Y++ISA K    +           S   H   ++    +            F  KVWD  +G  + S+ H HIV+ VDF+    +L+T +N+  + I DL++         GHT  I   +W  ++  + S   DK IR
Sbjct:    3 RQIPLSCSGHTRPVVDLHFSDITP-HGYFLISACKGEKRLEFHLKELSIFSSVHIHSRLLFVLLKNTKWWLQLFEGFFFFRKVWDALSGDEVASLPHKHIVKTVDFSSDGIRLLTGSNEKILRIFDLQNLDSEPQVLTGHTGSIKTALWNKENNMVYSGGDDKMIR 167

[Close]

BLAST of Serine/threonine kinase receptor associated protein vs. Ensembl Nematostella
Match: EDO47524 (Eukaryotic translation initiation factor 3 subunit I [Source:UniProtKB/Swiss-Prot;Acc:A7RM20])

HSP 1 Score: 75.0998 bits (183), Expect = 1.317e-15
Identity = 33/111 (29.73%), Postives = 64/111 (57.66%), Query Frame = 3

Query:  204 GHTRPVVDLHFSRLNDDKTYYVISASKDSVPMLRFGHTGDWIGSFKGHKGAVWSCTLSNDASKAATGAADFTAKVWDCENGKAITSIDHNHIVRCVDFNETANQLVTATNK 536
            GH R +  + ++R+ D     + SA+KD+ P + +   G+ +G++ GH GAVW   ++ D ++  +G AD   ++WDCE G  ++ I+    VR   F+   N+++ +T++
Sbjct:    8 GHERNITQIKYNRMGD----LLFSAAKDTRPTVWYSLNGERLGTYNGHGGAVWCIDVNYDTTQFISGGADNCLRLWDCEKGVTLSKIETKSAVRTCGFSYGGNEIMLSTDR 114

[Close]

BLAST of Serine/threonine kinase receptor associated protein vs. Ensembl Nematostella
Match: EDO47633 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RLM8])

HSP 1 Score: 68.9366 bits (167), Expect = 5.255e-13
Identity = 37/114 (32.46%), Postives = 64/114 (56.14%), Query Frame = 3

Query:  339 KGHKGAVWSCTLSNDASKAATGAADFTAKVWDCENGKAITSID-HNHIVRCVDFNETANQLVTATNKFGIEIHDLKSPGKPIMNFNGHTDMIHRTMWLNDDQKIISVSKDKTIR 677
            K H GAV+ C  S+D+SK  +   D   KVWD ++G+ + SI  H  +V C  F+   +++++ +    ++I D  S G+ ++ F GHT  +    +  DD K +S S D+T++
Sbjct:  604 KVHCGAVYCCKFSSDSSKVVSCGTDNHVKVWDSQSGRQLLSISGHGDVVNCCAFSHDDSRIISCSADQTVKIWD-ASSGEGVLCFVGHTQEVFSCSFSPDDTKAVSCSADRTVK 716

HSP 2 Score: 56.225 bits (134), Expect = 6.812e-9
Identity = 35/131 (26.72%), Postives = 65/131 (49.62%), Query Frame = 3

Query:  267 VISASKDSVPMLRFGHTGDWIGSFKGHKGAVWSCTLSNDASKAATGAADFTAKVWDCENGKAI-TSIDHNHIVRCVDFNETANQLVTATNKFGIEIHDLKSPGKPIMNFNGHTDMIHRTMWLNDDQKIISV 656
            +IS S D    +    +G+ +  F GH   V+SC+ S D +KA + +AD T KVWD + G      + H  IVR   F+    ++ + ++   + I +  S G+ +   + HT  +    ++N  + +++V
Sbjct:  664 IISCSADQTVKIWDASSGEGVLCFVGHTQEVFSCSFSPDDTKAVSCSADRTVKVWDSKTGVCYHVYMAHTDIVRWCCFSPDGGKVASCSDDNTVRIWE-ASSGEDLCLLDDHTSSVSFCCFMNQGESVVTV 793

HSP 3 Score: 49.2914 bits (116), Expect = 1.067e-6
Identity = 33/123 (26.83%), Postives = 58/123 (47.15%), Query Frame = 3

Query:  312 HTGDWIGSFKGHKGAVWSCTLSNDASKAATGAADFTAKVWDCENGKAITS-IDHNHIVRCVDFNETANQLVTATNKFGIEIHDLKSPGKPIMNFNGHTDMIHRTMWLNDDQKIISVSKDKTIR 677
             +G  + S  GH   V  C  S+D S+  + +AD T K+WD  +G+ +   + H   V    F+    + V+ +    +++ D K+ G     +  HTD++    +  D  K+ S S D T+R
Sbjct:  637 QSGRQLLSISGHGDVVNCCAFSHDDSRIISCSADQTVKIWDASSGEGVLCFVGHTQEVFSCSFSPDDTKAVSCSADRTVKVWDSKT-GVCYHVYMAHTDIVRWCCFSPDGGKVASCSDDNTVR 758

HSP 4 Score: 46.9802 bits (110), Expect = 6.044e-6
Identity = 32/115 (27.83%), Postives = 57/115 (49.57%), Query Frame = 3

Query:  327 IGSFKGHKGAVWSCTLSNDASKAATGAADFTAKVWDCENGKAITSID--HNHIVRCVDFNETANQLVTATNKFGIEIHDLKSPGKPIMNFNGHTDMIHRTMWLNDDQKIISVSKD 665
            + SF  HKGAV  C  S D     + + D TAKV++ +  + + ++    N + RC+ FN    +++TA+    +++ D K+        +  TD +      +D Q++IS S D
Sbjct:  973 LQSFSEHKGAVRRCYFSQDGQLLLSASDDKTAKVFNLQEARVMYTLAGHTNKLRRCMFFNND-TRILTASLDGSLKVWDAKTGNLEFTCCHSSTDYVLTCDVSHDSQRLISASAD 1086

[Close]

BLAST of Serine/threonine kinase receptor associated protein vs. Ensembl Nematostella
Match: EDO41499 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S4D0])

HSP 1 Score: 66.2402 bits (160), Expect = 3.006e-12
Identity = 38/109 (34.86%), Postives = 56/109 (51.38%), Query Frame = 3

Query:  357 VWSCTLSNDASKAATGAADFTAKVWDCENGKAITSIDHNHI--VRCVDFNETANQLVTATNKFGIEIHDLKSPGKPIMNFNGHTDMIHRTMWLNDDQKIISVSKDKTIR 677
            V   T S D+   A+G  D   KVW  + G+ +   +  H   V CV F+  A+QL++ +    I +H LKS GK +  F GHT  ++  ++  D   IIS S D TI+
Sbjct:  267 VLCLTFSRDSEMLASGGQDGKIKVWKLQTGQCLRRFERAHSKGVTCVTFSRDASQLLSGSFDMTIRMHGLKS-GKTLKEFRGHTSFVNDVIFTADAHHIISASSDGTIK 374

[Close]

BLAST of Serine/threonine kinase receptor associated protein vs. Ensembl Nematostella
Match: EDO41896 (Lissencephaly-1 homolog [Source:UniProtKB/Swiss-Prot;Acc:A7S338])

HSP 1 Score: 61.6178 bits (148), Expect = 7.551e-11
Identity = 43/160 (26.88%), Postives = 79/160 (49.38%), Query Frame = 3

Query:  201 SGHTRPVVDLHFSRLNDDKTYYVISASKDSVPMLRFGHTGDWIGSFKGHKGAVWSCTLSNDASKAATGAADFTAKVWDCENGKAITSI-DHNHIVRCVDFNETANQLVTATNKFGIEIHDLKSPGKPIMNFNGHTDMIHRTMWLNDDQKIISVSKDKTIR 677
            +GH  P+  + F  +       ++++S+D+   +    TGD+  + KGH  AV      +     A+ +AD T K+WD +  + I ++  H+H V  + F  + + LV+A+    I++ ++ + G  +  F GH + + R     D   I S S D+TIR
Sbjct:  103 TGHRSPITKVLFHPVYS----VMVTSSEDATVKVWDYETGDFERTLKGHTDAVQDLAFDHTGKFLASSSADMTIKLWDFQGFECIRTLHGHDHNVSSISFLPSGDHLVSASRDKTIKMWEIAT-GYCVKTFQGHGEWVRRVRPNADGSLIASCSNDQTIR 257

[Close]

BLAST of Serine/threonine kinase receptor associated protein vs. Ensembl Medaka
Match: strap (serine/threonine kinase receptor associated protein [Source:NCBI gene;Acc:101165272])

HSP 1 Score: 150.984 bits (380), Expect = 4.375e-43
Identity = 89/168 (52.98%), Postives = 113/168 (67.26%), Query Frame = 3

Query:  174 ALRQNSIQCSGHTRPVVDLHFSRLNDDKTYYVISASKDSVPMLRFGHTGDWIGSFKGHKGAVWSCTLSNDASKAATGAADFTAKVWDCENGKAITSIDHNHIVRCVDFNETANQLVTATNKFGIEIHDLKSPGKPIMNFNGHTDMIHRTMWLNDDQKIISVSKDKTIR 677
            A+RQ  + CSGHTRPVVDL FS +     Y++ISA KD  PMLR G TGDWIG+F GHKGAVW  TL+ DA+KAAT AADFTAKVWD  +G  + S+ H HIV+ V+F + +N L+TA N   + I DL +         GH   I + +W NDD++I+S + DKTIR
Sbjct:    2 AMRQTPLTCSGHTRPVVDLAFSGITP-FGYFLISACKDGKPMLRQGDTGDWIGTFLGHKGAVWGATLNMDATKAATAAADFTAKVWDSVSGDEVLSLAHKHIVKSVNFTQDSNHLLTAGNDKLLRIFDLSNTDAAPQEIAGHGAAIKKALWCNDDKQILSAADDKTIR 168

[Close]

BLAST of Serine/threonine kinase receptor associated protein vs. Ensembl Medaka
Match: strap (serine/threonine kinase receptor associated protein [Source:NCBI gene;Acc:101165272])

HSP 1 Score: 150.214 bits (378), Expect = 6.059e-43
Identity = 89/168 (52.98%), Postives = 113/168 (67.26%), Query Frame = 3

Query:  174 ALRQNSIQCSGHTRPVVDLHFSRLNDDKTYYVISASKDSVPMLRFGHTGDWIGSFKGHKGAVWSCTLSNDASKAATGAADFTAKVWDCENGKAITSIDHNHIVRCVDFNETANQLVTATNKFGIEIHDLKSPGKPIMNFNGHTDMIHRTMWLNDDQKIISVSKDKTIR 677
            A+RQ  + CSGHTRPVVDL FS +     Y++ISA KD  PMLR G TGDWIG+F GHKGAVW  TL+ DA+KAAT AADFTAKVWD  +G  + S+ H HIV+ V+F + +N L+TA N   + I DL +         GH   I + +W NDD++I+S + DKTIR
Sbjct:    2 AMRQTPLTCSGHTRPVVDLAFSGITP-FGYFLISACKDGKPMLRQGDTGDWIGTFLGHKGAVWGATLNMDATKAATAAADFTAKVWDSVSGDEVLSLAHKHIVKSVNFTQDSNHLLTAGNDKLLRIFDLSNTDAAPQEIAGHGAAIKKALWCNDDKQILSAADDKTIR 168

[Close]

BLAST of Serine/threonine kinase receptor associated protein vs. Ensembl Medaka
Match: EIF3I (eukaryotic translation initiation factor 3 subunit I [Source:NCBI gene;Acc:101173320])

HSP 1 Score: 69.707 bits (169), Expect = 3.087e-13
Identity = 42/155 (27.10%), Postives = 76/155 (49.03%), Query Frame = 3

Query:  192 IQCSGHTRPVVDLHFSRLNDDKTYYVISASKDSVPMLRFGHTGDWIGSFKGHKGAVWSCTLSNDASKAATGAADFTAKVWDCENGKAITSIDHNHIVRCVDFNETANQLVTATNK-FGIEIH----DLKSPGK-----PIMNFNGHTDMIHRTMW 626
            I   GH R +  + ++R  D     + S +KD+V    +   G+ +G++ GH GAVW      D     TG+AD + ++WDCE GK +  ++ +  VR   F+ + N ++ +T+K  G + +    DL+ P +     P ++   +   I   +W
Sbjct:    4 ILLQGHERSITQIKYNREGD----LLFSVAKDTVANAWYSVNGERLGTYNGHTGAVWCVDCDWDTKNVLTGSADNSCRLWDCETGKQLALLNTSSAVRTCGFDFSGNIIMFSTDKQMGYQCYLNFFDLRDPQQIEDNNPYLSVPCNESKITSAVW 154

[Close]

BLAST of Serine/threonine kinase receptor associated protein vs. Ensembl Medaka
Match: snrnp40 (small nuclear ribonucleoprotein U5 subunit 40 [Source:NCBI gene;Acc:101156339])

HSP 1 Score: 66.2402 bits (160), Expect = 4.558e-12
Identity = 49/166 (29.52%), Postives = 83/166 (50.00%), Query Frame = 3

Query:  183 QNSIQCSGHTRPVVDLHFSRLNDDKTYYVISASKDSVPMLRFGHTGDWIGSFKGHKGAVWSCTLSNDASK-AATGAADFTAKVWDCENGKAITSIDHNHIVRCVDFNETANQLVTATNKFGIEIHDLKSPGKPIMNFNGHTDMIHRTMWLNDDQKIISVSKDKTIR 677
            +N     GH+  V++LH+   N D +  + SAS D    +    TG+ I   KGH   V +C  +    +   TG+ D T K+WD     AI +  + + V  V FN+T++Q+++      I++ DL+   K I N +GH+D +      ++   ++S S D T+R
Sbjct:   90 ENYATLKGHSGAVMELHY---NTDGSL-LFSASTDKTVGIWDSETGERIKRLKGHTSFVNTCYPARRGPQLVCTGSDDGTIKLWDIRKKAAIHTFQNTYQVLAVTFNDTSDQILSGGIDNDIKVWDLRQ-NKLIYNMHGHSDSVTGLSLSSEGSYLLSNSMDNTVR 250

[Close]

BLAST of Serine/threonine kinase receptor associated protein vs. Ensembl Medaka
Match: snrnp40 (small nuclear ribonucleoprotein U5 subunit 40 [Source:NCBI gene;Acc:101156339])

HSP 1 Score: 66.2402 bits (160), Expect = 5.355e-12
Identity = 49/166 (29.52%), Postives = 83/166 (50.00%), Query Frame = 3

Query:  183 QNSIQCSGHTRPVVDLHFSRLNDDKTYYVISASKDSVPMLRFGHTGDWIGSFKGHKGAVWSCTLSNDASK-AATGAADFTAKVWDCENGKAITSIDHNHIVRCVDFNETANQLVTATNKFGIEIHDLKSPGKPIMNFNGHTDMIHRTMWLNDDQKIISVSKDKTIR 677
            +N     GH+  V++LH+   N D +  + SAS D    +    TG+ I   KGH   V +C  +    +   TG+ D T K+WD     AI +  + + V  V FN+T++Q+++      I++ DL+   K I N +GH+D +      ++   ++S S D T+R
Sbjct:  116 ENYATLKGHSGAVMELHY---NTDGSL-LFSASTDKTVGIWDSETGERIKRLKGHTSFVNTCYPARRGPQLVCTGSDDGTIKLWDIRKKAAIHTFQNTYQVLAVTFNDTSDQILSGGIDNDIKVWDLRQ-NKLIYNMHGHSDSVTGLSLSSEGSYLLSNSMDNTVR 276

[Close]

BLAST of Serine/threonine kinase receptor associated protein vs. Planmine SMEST
Match: SMESG000035983.1 (SMESG000035983.1)

HSP 1 Score: 367.466 bits (942), Expect = 1.448e-128
Identity = 175/175 (100.00%), Postives = 175/175 (100.00%), Query Frame = 3

Query:  153 MEKLNNKALRQNSIQCSGHTRPVVDLHFSRLNDDKTYYVISASKDSVPMLRFGHTGDWIGSFKGHKGAVWSCTLSNDASKAATGAADFTAKVWDCENGKAITSIDHNHIVRCVDFNETANQLVTATNKFGIEIHDLKSPGKPIMNFNGHTDMIHRTMWLNDDQKIISVSKDKTIR 677
            MEKLNNKALRQNSIQCSGHTRPVVDLHFSRLNDDKTYYVISASKDSVPMLRFGHTGDWIGSFKGHKGAVWSCTLSNDASKAATGAADFTAKVWDCENGKAITSIDHNHIVRCVDFNETANQLVTATNKFGIEIHDLKSPGKPIMNFNGHTDMIHRTMWLNDDQKIISVSKDKTIR
Sbjct:    1 MEKLNNKALRQNSIQCSGHTRPVVDLHFSRLNDDKTYYVISASKDSVPMLRFGHTGDWIGSFKGHKGAVWSCTLSNDASKAATGAADFTAKVWDCENGKAITSIDHNHIVRCVDFNETANQLVTATNKFGIEIHDLKSPGKPIMNFNGHTDMIHRTMWLNDDQKIISVSKDKTIR 175

[Close]

BLAST of Serine/threonine kinase receptor associated protein vs. Planmine SMEST
Match: SMESG000034899.1 (SMESG000034899.1)

HSP 1 Score: 65.855 bits (159), Expect = 4.847e-12
Identity = 35/125 (28.00%), Postives = 61/125 (48.80%), Query Frame = 3

Query:  159 KLNNKALRQNSIQCSGHTRPVVDLHFSRLNDDKTYYVISASKDSVPMLRFGHTGDWIGSFKGHKGAVWSCTLSNDASKAATGAADFTAKVWDCENGKAITSIDHNHIVRCVDFNETANQLVTATN 533
            K   K  ++  +   GH RP+  + ++R  D     + + +K+  P + +   G+ +G++ GHKGAVW   +  +     TGAAD +  +WD E G  + SI     VR   F  + N ++  T+
Sbjct:   10 KFKLKISKKRPLILQGHERPITQVKYNREGD----LLFTIAKEKEPNVWYTVNGERLGTYDGHKGAVWCLDVDWETRFLITGAADDSLNIWDIETGTLLNSIRTLTSVRSCQFGYSGNTILMTTD 130

[Close]

BLAST of Serine/threonine kinase receptor associated protein vs. Planmine SMEST
Match: SMESG000034899.1 (SMESG000034899.1)

HSP 1 Score: 65.0846 bits (157), Expect = 1.304e-11
Identity = 34/117 (29.06%), Postives = 58/117 (49.57%), Query Frame = 3

Query:  183 QNSIQCSGHTRPVVDLHFSRLNDDKTYYVISASKDSVPMLRFGHTGDWIGSFKGHKGAVWSCTLSNDASKAATGAADFTAKVWDCENGKAITSIDHNHIVRCVDFNETANQLVTATN 533
            Q  +   GH RP+  + ++R  D     + + +K+  P + +   G+ +G++ GHKGAVW   +  +     TGAAD +  +WD E G  + SI     VR   F  + N ++  T+
Sbjct:  264 QRPLILQGHERPITQVKYNREGD----LLFTIAKEKEPNVWYTVNGERLGTYDGHKGAVWCLDVDWETRFLITGAADDSLNIWDIETGTLLNSIRTLTSVRSCQFGYSGNTILMTTD 376

[Close]

BLAST of Serine/threonine kinase receptor associated protein vs. Planmine SMEST
Match: SMESG000034899.1 (SMESG000034899.1)

HSP 1 Score: 63.929 bits (154), Expect = 2.023e-11
Identity = 33/111 (29.73%), Postives = 56/111 (50.45%), Query Frame = 3

Query:  201 SGHTRPVVDLHFSRLNDDKTYYVISASKDSVPMLRFGHTGDWIGSFKGHKGAVWSCTLSNDASKAATGAADFTAKVWDCENGKAITSIDHNHIVRCVDFNETANQLVTATN 533
             GH RP+  + ++R  D     + + +K+  P + +   G+ +G++ GHKGAVW   +  +     TGAAD +  +WD E G  + SI     VR   F  + N ++  T+
Sbjct:    7 QGHERPITQVKYNREGD----LLFTIAKEKEPNVWYTVNGERLGTYDGHKGAVWCLDVDWETRFLITGAADDSLNIWDIETGTLLNSIRTLTSVRSCQFGYSGNTILMTTD 113

[Close]

BLAST of Serine/threonine kinase receptor associated protein vs. Planmine SMEST
Match: SMESG000034899.1 (SMESG000034899.1)

HSP 1 Score: 63.929 bits (154), Expect = 2.344e-11
Identity = 33/111 (29.73%), Postives = 56/111 (50.45%), Query Frame = 3

Query:  201 SGHTRPVVDLHFSRLNDDKTYYVISASKDSVPMLRFGHTGDWIGSFKGHKGAVWSCTLSNDASKAATGAADFTAKVWDCENGKAITSIDHNHIVRCVDFNETANQLVTATN 533
             GH RP+  + ++R  D     + + +K+  P + +   G+ +G++ GHKGAVW   +  +     TGAAD +  +WD E G  + SI     VR   F  + N ++  T+
Sbjct:   18 QGHERPITQVKYNREGD----LLFTIAKEKEPNVWYTVNGERLGTYDGHKGAVWCLDVDWETRFLITGAADDSLNIWDIETGTLLNSIRTLTSVRSCQFGYSGNTILMTTD 124

The following BLAST results are available for this feature:

BLAST of Serine/threonine kinase receptor associated protein vs. Ensembl Human
BLAST of Serine/threonine kinase receptor associated protein vs. Ensembl Celegans
BLAST of Serine/threonine kinase receptor associated protein vs. Ensembl Fly
BLAST of Serine/threonine kinase receptor associated protein vs. Ensembl Zebrafish
BLAST of Serine/threonine kinase receptor associated protein vs. Ensembl Xenopus
BLAST of Serine/threonine kinase receptor associated protein vs. Ensembl Mouse
BLAST of Serine/threonine kinase receptor associated protein vs. UniProt/SwissProt
BLAST of Serine/threonine kinase receptor associated protein vs. TrEMBL
BLAST of Serine/threonine kinase receptor associated protein vs. Ensembl Cavefish
BLAST of Serine/threonine kinase receptor associated protein vs. Ensembl Sea Lamprey
BLAST of Serine/threonine kinase receptor associated protein vs. Ensembl Yeast
BLAST of Serine/threonine kinase receptor associated protein vs. Ensembl Nematostella
BLAST of Serine/threonine kinase receptor associated protein vs. Ensembl Medaka
BLAST of Serine/threonine kinase receptor associated protein vs. Planmine SMEST

BLAST of Serine/threonine kinase receptor associated protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
STRAP	2.939e-41	51.19	serine/threonine kinase receptor associated protei...	[more]
STRAP	1.242e-37	47.51	serine/threonine kinase receptor associated protei...	[more]
EIF3I	1.971e-13	29.57	eukaryotic translation initiation factor 3 subunit...	[more]
EIF3I	1.711e-12	27.10	eukaryotic translation initiation factor 3 subunit...	[more]
NLE1	1.265e-11	25.84	notchless homolog 1 [Source:HGNC Symbol;Acc:HGNC:1...	[more]

BLAST of Serine/threonine kinase receptor associated protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5


Match Name	E-value	Identity	Description
eif-3.I	1.329e-14	28.89	Eukaryotic translation initiation factor 3 subunit...	[more]
qui-1	3.887e-8	29.94	QUInine non-avoider [Source:UniProtKB/TrEMBL;Acc:...	[more]
qui-1	4.794e-8	30.13	QUInine non-avoider [Source:UniProtKB/TrEMBL;Acc:...	[more]
W07E6.2	9.774e-8	29.51	pep chromosome:WBcel235:II:480722:483104:-1 gene:W...	[more]
smu-1	2.214e-7	30.63	Smu-1 suppressor of mec-8 and unc-52 protein [Sou...	[more]

BLAST of Serine/threonine kinase receptor associated protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5


Match Name	E-value	Identity	Description
wmd	8.224e-49	48.50	gene:FBgn0034876 transcript:FBtr0113112	[more]
wmd	8.224e-49	48.50	gene:FBgn0034876 transcript:FBtr0072114	[more]
CG10459	8.576e-27	35.76	gene:FBgn0033440 transcript:FBtr0088468	[more]
eIF3i	1.237e-16	29.70	gene:FBgn0015834 transcript:FBtr0079053	[more]
wds	2.280e-10	26.25	gene:FBgn0040066 transcript:FBtr0308566	[more]

BLAST of Serine/threonine kinase receptor associated protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
strap	5.939e-46	52.38	serine/threonine kinase receptor associated protei...	[more]
eif3i	1.445e-13	29.01	eukaryotic translation initiation factor 3, subuni...	[more]
nle1	5.799e-12	28.09	notchless homolog 1 (Drosophila) [Source:ZFIN;Acc:...	[more]
nle1	5.799e-12	28.09	notchless homolog 1 (Drosophila) [Source:ZFIN;Acc:...	[more]
nle1	5.799e-12	28.09	notchless homolog 1 (Drosophila) [Source:ZFIN;Acc:...	[more]

BLAST of Serine/threonine kinase receptor associated protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5


Match Name	E-value	Identity	Description
strap	4.797e-44	51.50	serine/threonine kinase receptor associated protei...	[more]
eif3i	1.308e-12	26.83	eukaryotic translation initiation factor 3 subunit...	[more]
eif3i	1.308e-12	26.83	eukaryotic translation initiation factor 3 subunit...	[more]
ppp6c	4.469e-11	32.73	protein phosphatase 6, catalytic subunit [Source:X...	[more]
ppp6c	4.477e-11	32.73	protein phosphatase 6, catalytic subunit [Source:X...	[more]

BLAST of Serine/threonine kinase receptor associated protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Strap	4.416e-42	51.79	serine/threonine kinase receptor associated protei...	[more]
Eif3i	1.163e-12	27.10	eukaryotic translation initiation factor 3, subuni...	[more]
Smu1	1.472e-11	33.64	smu-1 suppressor of mec-8 and unc-52 homolog (C. e...	[more]
Apaf1	6.179e-11	29.61	apoptotic peptidase activating factor 1 [Source:MG...	[more]
Apaf1	6.179e-11	29.61	apoptotic peptidase activating factor 1 [Source:MG...	[more]

BLAST of Serine/threonine kinase receptor associated protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|Q54LT8\|STRAP_DICDI	1.159e-41	44.64	Serine-threonine kinase receptor-associated protei...	[more]
sp\|Q9Z1Z2\|STRAP_MOUSE	3.089e-41	51.79	Serine-threonine kinase receptor-associated protei...	[more]
sp\|Q5XIG8\|STRAP_RAT	1.084e-40	51.19	Serine-threonine kinase receptor-associated protei...	[more]
sp\|Q5E959\|STRAP_BOVIN	1.192e-40	51.19	Serine-threonine kinase receptor-associated protei...	[more]
sp\|Q9Y3F4\|STRAP_HUMAN	1.411e-40	51.19	Serine-threonine kinase receptor-associated protei...	[more]

BLAST of Serine/threonine kinase receptor associated protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
T1FM24	3.203e-56	55.95	WD_REPEATS_REGION domain-containing protein OS=Hel...	[more]
T1K495	4.671e-54	55.36	WD_REPEATS_REGION domain-containing protein OS=Tet...	[more]
T1K499	1.612e-53	55.36	WD_REPEATS_REGION domain-containing protein OS=Tet...	[more]
A0A023FLZ8	1.992e-53	54.12	Putative serine/threonine kinase receptor-associat...	[more]
A0A0C9S2N0	3.745e-53	53.85	Putative serine/threonine kinase receptor-associat...	[more]

BLAST of Serine/threonine kinase receptor associated protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
strap	5.508e-49	50.60	serine/threonine kinase receptor associated protei...	[more]
eif3i	6.229e-14	29.77	eukaryotic translation initiation factor 3 subunit...	[more]
smu1a	6.348e-12	34.55	SMU1 DNA replication regulator and spliceosomal fa...	[more]
snrnp40	1.025e-10	27.71	small nuclear ribonucleoprotein U5 subunit 40 [Sou...	[more]
wdr5	1.213e-10	26.25	WD repeat domain 5 [Source:NCBI gene;Acc:103033424...	[more]

BLAST of Serine/threonine kinase receptor associated protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5


Match Name	E-value	Identity	Description
strap	5.862e-41	52.38	serine/threonine kinase receptor associated protei...	[more]
pafah1b1b	1.901e-10	26.88	platelet-activating factor acetylhydrolase 1b, reg...	[more]
snrnp40	1.210e-9	26.67	small nuclear ribonucleoprotein 40 (U5) [Source:ZF...	[more]
ENSPMAT00000004902.1	2.033e-7	22.91	pep scaffold:Pmarinus_7.0:GL478254:5937:33805:1 ge...	[more]
ENSPMAT00000008862.1	4.026e-7	23.91	pep scaffold:Pmarinus_7.0:GL476579:86637:114999:1 ...	[more]

BLAST of Serine/threonine kinase receptor associated protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 3


Match Name	E-value	Identity	Description
TIF34	4.360e-12	26.56	eIF3i subunit of the eukaryotic translation initia...	[more]
ASC1	5.802e-8	26.67	G-protein beta subunit and guanine dissociation in...	[more]
RSA4	8.951e-6	24.14	WD-repeat protein involved in ribosome biogenesis;...	[more]

BLAST of Serine/threonine kinase receptor associated protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5


Match Name	E-value	Identity	Description
EDO27706	2.901e-19	31.93	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO47524	1.317e-15	29.73	Eukaryotic translation initiation factor 3 subunit...	[more]
EDO47633	5.255e-13	32.46	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO41499	3.006e-12	34.86	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO41896	7.551e-11	26.88	Lissencephaly-1 homolog [Source:UniProtKB/Swiss-P...	[more]

BLAST of Serine/threonine kinase receptor associated protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5


Match Name	E-value	Identity	Description
strap	4.375e-43	52.98	serine/threonine kinase receptor associated protei...	[more]
strap	6.059e-43	52.98	serine/threonine kinase receptor associated protei...	[more]
EIF3I	3.087e-13	27.10	eukaryotic translation initiation factor 3 subunit...	[more]
snrnp40	4.558e-12	29.52	small nuclear ribonucleoprotein U5 subunit 40 [Sou...	[more]
snrnp40	5.355e-12	29.52	small nuclear ribonucleoprotein U5 subunit 40 [Sou...	[more]

BLAST of Serine/threonine kinase receptor associated protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5


Match Name	E-value	Identity	Description
SMESG000035983.1	1.448e-128	100.00	SMESG000035983.1	[more]
SMESG000034899.1	4.847e-12	28.00	SMESG000034899.1	[more]
SMESG000034899.1	1.304e-11	29.06	SMESG000034899.1	[more]
SMESG000034899.1	2.023e-11	29.73	SMESG000034899.1	[more]
SMESG000034899.1	2.344e-11	29.73	SMESG000034899.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30027898 ID=SMED30027898|Name=Serine/threonine kinase receptor associated protein|organism=Schmidtea mediterranea sexual|type=transcript|length=889bp
ATTTAATGTGTTTATTTTCTAAAATGAATAAAAACTCATTTTTCAACATT
CAATCTTTTTAGTTCTTCTTGACTATTGTTTTAACATTTTATTATTCGTT
TATTGAGTTTAATATGATAATTATGTTTTTAATATTTTAGCAAATTTACA
CAATGGAAAAGCTAAATAATAAAGCACTCAGACAAAACTCTATTCAATGC
TCGGGTCATACGAGACCAGTTGTTGATTTACATTTTAGTCGTTTAAATGA
TGATAAAACATATTATGTAATATCTGCTAGCAAAGACAGTGTTCCAATGC
TACGGTTCGGTCACACTGGTGATTGGATAGGCAGCTTTAAAGGACATAAA
GGAGCTGTTTGGTCATGCACTTTATCGAACGATGCTTCAAAAGCTGCAAC
TGGTGCTGCTGATTTCACAGCTAAAGTTTGGGATTGTGAAAATGGTAAAG
CTATTACTTCAATCGATCACAACCACATTGTACGATGTGTTGATTTTAAT
GAAACTGCTAATCAGTTAGTGACTGCTACCAACAAATTTGGAATTGAAAT
TCACGATTTAAAATCACCTGGAAAACCTATAATGAATTTCAACGGCCATA
CCGACATGATCCATCGAACGATGTGGCTCAATGATGATCAGAAAATAATA
TCGGTATCCAAAGATAAAACAATAAGGTCATCATAATTCCTAATTTTGAG
TTTATTTTAATTGTAAAAATGTTAAATAATATTCAACGTATCAGCTGATT
ATTTAATTGTACTTTTTGAGTTACCCACTTTAATTTGATTAAATCTAGTT
TTATATTTACAAAGAATTAGAGTTGCTTAATAAATTGAAAAATGGACTAT
TAAAATTCTTAAAAAAATTACTATTTTGATAATTTACAC

protein sequence of SMED30027898-orf-1

>SMED30027898-orf-1 ID=SMED30027898-orf-1|Name=SMED30027898-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=178bp
MEKLNNKALRQNSIQCSGHTRPVVDLHFSRLNDDKTYYVISASKDSVPML
RFGHTGDWIGSFKGHKGAVWSCTLSNDASKAATGAADFTAKVWDCENGKA
ITSIDHNHIVRCVDFNETANQLVTATNKFGIEIHDLKSPGKPIMNFNGHT
DMIHRTMWLNDDQKIISVSKDKTIRSS*

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0002109	X1 cell
PLANA:0002111	X2 cell

Vocabulary: **INTERPRO**
Term	Definition
IPR036322	WD40_repeat_dom_sf
IPR011528	NERD
IPR001680	WD40_repeat
IPR015943	WD40/YVTN_repeat-like_dom_sf
IPR019775	WD40_repeat_CS
IPR017986	WD40_repeat_dom

Vocabulary: **molecular function**
Term	Definition
GO:0005515	protein binding
GO:0016301	kinase activity

Vocabulary: **biological process**
Term	Definition
GO:0016310	phosphorylation

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR001680	WD40 repeat	SMART	SM00320	WD40_4	coord: 55..94 e-value: 2.9E-6 score: 36.8 coord: 9..54 e-value: 230.0 score: 2.1 coord: 97..135 e-value: 0.8 score: 17.6 coord: 139..176 e-value: 3.0 score: 14.0
IPR001680	WD40 repeat	PFAM	PF00400	WD40	coord: 59..94 e-value: 4.6E-4 score: 20.9
IPR001680	WD40 repeat	PROSITE	PS50082	WD_REPEATS_2	coord: 62..103 score: 12.681
IPR015943	WD40/YVTN repeat-like-containing domain superfamily	GENE3D	G3DSA:2.130.10.10		coord: 12..143 e-value: 6.2E-31 score: 109.8
None	No IPR available	PANTHER	PTHR19877	WD40 REPEAT PROTEIN	coord: 11..174
None	No IPR available	PANTHER	PTHR19877:SF4	F9L1.42 PROTEIN	coord: 11..174
IPR019775	WD40 repeat, conserved site	PROSITE	PS00678	WD_REPEATS_1	coord: 81..95
IPR017986	WD40-repeat-containing domain	PROSITE	PS50294	WD_REPEATS_REGION	coord: 62..177 score: 13.923
IPR036322	WD40-repeat-containing domain superfamily	SUPERFAMILY	SSF50978	WD40 repeat-like	coord: 14..175