Immunoglobulin superfamily member 10

Overview
NameImmunoglobulin superfamily member 10
Smed IDSMED30027888
Length (bp)2009
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Immunoglobulin superfamily member 10 (SMED30027888) t-SNE clustered cells

Violin plots show distribution of expression levels for Immunoglobulin superfamily member 10 (SMED30027888) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Immunoglobulin superfamily member 10 (SMED30027888) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Immunoglobulin superfamily member 10 (SMED30027888) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30027888

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 12

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
central nervous systemSMED30027888SMESG000021154.1 dd_Smed_v4_8690_0_1dd_Smed_v4PMID:27063937
Scimone et al., 2016		whole organism asexual adult colorimetric in situ hybridization evidence
midlineSMED30027888SMESG000021154.1 dd_Smed_v4_8690_0_1dd_Smed_v4PMID:27063937
Scimone et al., 2016		whole organism asexual adult colorimetric in situ hybridization evidence
head regionSMED30027888SMESG000021154.1 SmedASXL_019619SmedAsxl_ww_GCZZ01PMID:27034770
Currie et al., 2016		whole organism asexual adult RNA-sequencing evidence
nervous systemSMED30027888SMESG000021154.1 dd_Smed_v4_8690_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30027888SMESG000021154.1 dd_Smed_v4_8690_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
neuronSMED30027888SMESG000021154.1 dd_Smed_v4_8690_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		whole organism asexual adult colorimetric in situ hybridization evidence
muscle cellSMED30027888SMESG000021154.1 dd_Smed_v4_8690_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cilated neuronSMED30027888SMESG000021154.1 dd_Smed_v4_8690_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30027888SMESG000048912.1 Contig4782GPL15192PMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30027888SMESG000021154.1 Contig4782GPL15192PMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
head regionSMED30027888SMESG000021154.1 dd_Smed_v6_8690_0_1dd_Smed_v6PMID:28171748
Stückemann et al., 2017		whole organism asexual adult RNA-sequencing evidence
epidermisSMED30027888SMESG000021154.1 dd_Smed_v4_8690_0_1dd_Smed_v4PMID:28292427
Wurtzel et al., 2017		whole organism asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Immunoglobulin superfamily member 10 vs. Ensembl Human
Match: LRRC4 (leucine rich repeat containing 4 [Source:HGNC Symbol;Acc:HGNC:15586])

HSP 1 Score: 63.929 bits (154), Expect = 6.435e-10
Identity = 68/266 (25.56%), Postives = 108/266 (40.60%), Query Frame = 1 
Query:  589 GLDFLDFSENLKLYIENRAFDNLKLKHLKLDFIGNLEFS---EDAFQGLL-VASLTIAKSHLQALPYRLIEPLSRELRXXXXXXXXXXXXXXXXESLFRQLTILDLHGNPFICSCNMLWLGVTLKWRQNYYRSNTNSFSEPQFPKCDKPYYLLNQYLYEIPETEFNCRSPKLDRI--EVQFKSQQSAVLKCAASLESKRAPM-KISWL-----YLSSKEYVPNLLPSSKSNEAEIEITQKHYIDQ--YFCSVSSAAGNASVKVNFN 1344
            GL+ L+ S N    I   +F  L    LK  ++ N + S    +AF GL  +  L +A ++L +LP+ L  PL                         R L  L LH NP+ C C++LWL     W + Y  +N+         +C  P ++  +YL E+ +  F C +P +     ++     + A LKC      +  PM  + WL      LS     P +   S  N+  +  +     D   Y C V++ AGN++     N
Sbjct:  219 GLEELEMSGNHFPEIRPGSFHGLS--SLKKLWVMNSQVSLIERNAFDGLASLVELNLAHNNLSSLPHDLFTPL-------------------------RYLVELHLHHNPWNCDCDILWLA---WWLREYIPTNSTCCG-----RCHAPMHMRGRYLVEVDQASFQCSAPFIMDAPRDLNISEGRMAELKC------RTPPMSSVKWLLPNGTVLSHASRHPRI---SVLNDGTLNFSHVLLSDTGVYTCMVTNVAGNSNASAYLN 440
[Close]
BLAST of Immunoglobulin superfamily member 10 vs. Ensembl Human
Match: LGI4 (leucine rich repeat LGI family member 4 [Source:HGNC Symbol;Acc:HGNC:18712])

HSP 1 Score: 53.9138 bits (128), Expect = 3.454e-7
Identity = 50/175 (28.57%), Postives = 71/175 (40.57%), Query Frame = 1 
Query:  571 TFYDVSGLDFLDFSENLKLYIENRAFDNLKLKHLKLDFIGNLEF---SEDAFQGLL-VASLTIAKSHLQALPYRLIEPLSRELRXXXXXXXXXXXXXXXXESLFRQLTILDLHGNPFICSCNMLWLGVTLKWRQNYYRSNTNSFSEPQFPKCDKPYYLLNQYLYEIPETEFNCRS 1083
            +F  +  L  L F+ N    IE+ AF  L   HL+  FI + E    S++A +GL  +  L++A +HL+ LP  L   L                           LT +DL GNPF C C +LWL   L+W      S            C  P  L +  L+ +    F CR+
Sbjct:   71 SFLRIPSLHLLLFTSNSFSVIEDDAFAGLS--HLQYLFIEDNEIGSISKNALRGLRSLTHLSLANNHLETLPRFLFRGLD-------------------------TLTHVDLRGNPFQCDCRVLWL---LQWMPTVNASVGTG-------ACAGPASLSHMQLHHLDPKTFKCRA 208
[Close]
BLAST of Immunoglobulin superfamily member 10 vs. Ensembl Human
Match: LGI4 (leucine rich repeat LGI family member 4 [Source:HGNC Symbol;Acc:HGNC:18712])

HSP 1 Score: 54.299 bits (129), Expect = 5.165e-7
Identity = 51/178 (28.65%), Postives = 73/178 (41.01%), Query Frame = 1 
Query:  571 TFYDVSGLDFLDFSENLKLYIENRAFDNLKLKHLKLDFIGNLEF---SEDAFQGLL-VASLTIAKSHLQALPYRLIEPLSRELRXXXXXXXXXXXXXXXXESLFRQLTILDLHGNPFICSCNMLWLGVTLKWRQNYYRSNTNSFSEPQFPKCDKPYYLLNQYLYEIPETEFNCRSPKL 1092
            +F  +  L  L F+ N    IE+ AF  L   HL+  FI + E    S++A +GL  +  L++A +HL+ LP  L   L                           LT +DL GNPF C C +LWL   L+W      S            C  P  L +  L+ +    F CR+ +L
Sbjct:   71 SFLRIPSLHLLLFTSNSFSVIEDDAFAGLS--HLQYLFIEDNEIGSISKNALRGLRSLTHLSLANNHLETLPRFLFRGLD-------------------------TLTHVDLRGNPFQCDCRVLWL---LQWMPTVNASVGTG-------ACAGPASLSHMQLHHLDPKTFKCRAIEL 211
[Close]
BLAST of Immunoglobulin superfamily member 10 vs. Ensembl Human
Match: LGI4 (leucine rich repeat LGI family member 4 [Source:HGNC Symbol;Acc:HGNC:18712])

HSP 1 Score: 54.299 bits (129), Expect = 5.752e-7
Identity = 53/190 (27.89%), Postives = 77/190 (40.53%), Query Frame = 1 
Query:  571 TFYDVSGLDFLDFSENLKLYIENRAFDNLKLKHLKLDFIGNLEF---SEDAFQGLL-VASLTIAKSHLQALPYRLIEPLSRELRXXXXXXXXXXXXXXXXESLFRQLTILDLHGNPFICSCNMLWLGVTLKWRQNYYRSNTNSFSEPQFPKCDKPYYLLNQYLYEIPETEFNCRSPKLDRIEVQFKSQQS 1128
            +F  +  L  L F+ N    IE+ AF  L   HL+  FI + E    S++A +GL  +  L++A +HL+ LP  L   L                           LT +DL GNPF C C +LWL   L+W      S            C  P  L +  L+ +    F CR+ +L   +   +S  S
Sbjct:   71 SFLRIPSLHLLLFTSNSFSVIEDDAFAGLS--HLQYLFIEDNEIGSISKNALRGLRSLTHLSLANNHLETLPRFLFRGLD-------------------------TLTHVDLRGNPFQCDCRVLWL---LQWMPTVNASVGTG-------ACAGPASLSHMQLHHLDPKTFKCRAIELSWFQTVGESALS 223
[Close]
BLAST of Immunoglobulin superfamily member 10 vs. Ensembl Human
Match: LRRC4B (leucine rich repeat containing 4B [Source:HGNC Symbol;Acc:HGNC:25042])

HSP 1 Score: 52.373 bits (124), Expect = 2.593e-6
Identity = 61/266 (22.93%), Postives = 104/266 (39.10%), Query Frame = 1 
Query:  592 LDFLDFSENLKLYIENRAFDNL-KLKHLKLDFIGNLEFSEDAFQGLL-VASLTIAKSHLQALPYRLIEPLSRELRXXXXXXXXXXXXXXXXESLFRQLTILDLHGNPFICSCNMLWLGVTLKWRQNYYRSNTNSFSEPQFPKCDKPYYLLNQYLYEIPETEFNCRSPKLDR--IEVQFKSQQSAVLKCAASLESKRAPMKISWLYLSSKEYVPN-LLPSSKSNEAEIEITQKHYID----------QYFCSVSSAAGNASVKVNFN 1344
            L+ L+ S N    I   +F  L  L+ L L          +AF  L  +  L ++ ++L +LP+ L  PL R                         L  + L+ NP+ C+C++LWL     W +    SNT   +     +C  P  L  +Y+ E+ ++ F C +P +     ++      +A LKC     +  +   ++WL        PN  L +  S    I +     ++          QY C V+++AGN +     N
Sbjct:  231 LEELELSGNRLDLIRPGSFQGLTSLRKLWLMHAQVATIERNAFDDLKSLEELNLSHNNLMSLPHDLFTPLHR-------------------------LERVHLNHNPWHCNCDVLWLSW---WLKETVPSNTTCCA-----RCHAPAGLKGRYIGELDQSHFTCYAPVIVEPPTDLNVTEGMAAELKC----RTGTSMTSVNWL-------TPNGTLMTHGSYRVRISVLHDGTLNFTNVTVQDTGQYTCMVTNSAGNTTASATLN 452
[Close]
BLAST of Immunoglobulin superfamily member 10 vs. Ensembl Fly
Match: sli (gene:FBgn0264089 transcript:FBtr0330730)

HSP 1 Score: 66.6254 bits (161), Expect = 6.355e-11
Identity = 64/248 (25.81%), Postives = 105/248 (42.34%), Query Frame = 1 
Query:  340 CPNVCTPCLEHAITCENGGLDGIPTELYEETTRVILVGHKFSQTFLSRQNFSKFTKPKYSIEXXXXXXXXXXXXXXXTFYDVSGLDFLDFSENLKLYIENRAFDNLK-LKHLKLDFIGNLEFSEDAFQGLL-VASLTIAKSHLQALPYRLIEPLSRELRXXXXXXXXXXXXXXXXESLFRQLTILDLHGNPFICSCNMLWLGVTLKWRQNYYRSNTNSFSEPQFPKCDKPYYLLNQYLYEIPETEFNC 1077
            CP VC+ C    + C + GL  +P ++  +  R+ L G+    T +   +F + TK    +  L +  + I  I   +F D+  L+ LD S N+   +  R F   + L+ L+LD        E AF+GL+ +  LT+  ++L +LP+ +   L R                         L  L L  NPF C C++ WL         + RS T       + +C  P  L  Q + ++ + EF C
Sbjct:   73 CPRVCS-CTGLNVDCSHRGLTSVPRKISADVERLELQGNNL--TVIYETDFQRLTK----LRMLQLTDNQIHTIERNSFQDLVSLERLDISNNVITTVGRRVFKGAQSLRSLQLDNNQITCLDEHAFKGLVELEILTLNNNNLTSLPHNIFGGLGR-------------------------LRALRLSDNPFACDCHLSWL-------SRFLRSATRL---APYTRCQSPSQLKGQNVADLHDQEFKC 278
[Close]
BLAST of Immunoglobulin superfamily member 10 vs. Ensembl Fly
Match: sli (gene:FBgn0264089 transcript:FBtr0330729)

HSP 1 Score: 66.6254 bits (161), Expect = 6.587e-11
Identity = 64/248 (25.81%), Postives = 105/248 (42.34%), Query Frame = 1 
Query:  340 CPNVCTPCLEHAITCENGGLDGIPTELYEETTRVILVGHKFSQTFLSRQNFSKFTKPKYSIEXXXXXXXXXXXXXXXTFYDVSGLDFLDFSENLKLYIENRAFDNLK-LKHLKLDFIGNLEFSEDAFQGLL-VASLTIAKSHLQALPYRLIEPLSRELRXXXXXXXXXXXXXXXXESLFRQLTILDLHGNPFICSCNMLWLGVTLKWRQNYYRSNTNSFSEPQFPKCDKPYYLLNQYLYEIPETEFNC 1077
            CP VC+ C    + C + GL  +P ++  +  R+ L G+    T +   +F + TK    +  L +  + I  I   +F D+  L+ LD S N+   +  R F   + L+ L+LD        E AF+GL+ +  LT+  ++L +LP+ +   L R                         L  L L  NPF C C++ WL         + RS T       + +C  P  L  Q + ++ + EF C
Sbjct:   73 CPRVCS-CTGLNVDCSHRGLTSVPRKISADVERLELQGNNL--TVIYETDFQRLTK----LRMLQLTDNQIHTIERNSFQDLVSLERLDISNNVITTVGRRVFKGAQSLRSLQLDNNQITCLDEHAFKGLVELEILTLNNNNLTSLPHNIFGGLGR-------------------------LRALRLSDNPFACDCHLSWL-------SRFLRSATRL---APYTRCQSPSQLKGQNVADLHDQEFKC 278
[Close]
BLAST of Immunoglobulin superfamily member 10 vs. Ensembl Fly
Match: sli (gene:FBgn0264089 transcript:FBtr0330732)

HSP 1 Score: 66.6254 bits (161), Expect = 6.587e-11
Identity = 64/248 (25.81%), Postives = 105/248 (42.34%), Query Frame = 1 
Query:  340 CPNVCTPCLEHAITCENGGLDGIPTELYEETTRVILVGHKFSQTFLSRQNFSKFTKPKYSIEXXXXXXXXXXXXXXXTFYDVSGLDFLDFSENLKLYIENRAFDNLK-LKHLKLDFIGNLEFSEDAFQGLL-VASLTIAKSHLQALPYRLIEPLSRELRXXXXXXXXXXXXXXXXESLFRQLTILDLHGNPFICSCNMLWLGVTLKWRQNYYRSNTNSFSEPQFPKCDKPYYLLNQYLYEIPETEFNC 1077
            CP VC+ C    + C + GL  +P ++  +  R+ L G+    T +   +F + TK    +  L +  + I  I   +F D+  L+ LD S N+   +  R F   + L+ L+LD        E AF+GL+ +  LT+  ++L +LP+ +   L R                         L  L L  NPF C C++ WL         + RS T       + +C  P  L  Q + ++ + EF C
Sbjct:   73 CPRVCS-CTGLNVDCSHRGLTSVPRKISADVERLELQGNNL--TVIYETDFQRLTK----LRMLQLTDNQIHTIERNSFQDLVSLERLDISNNVITTVGRRVFKGAQSLRSLQLDNNQITCLDEHAFKGLVELEILTLNNNNLTSLPHNIFGGLGR-------------------------LRALRLSDNPFACDCHLSWL-------SRFLRSATRL---APYTRCQSPSQLKGQNVADLHDQEFKC 278
[Close]
BLAST of Immunoglobulin superfamily member 10 vs. Ensembl Zebrafish
Match: lrrc4.2 (leucine rich repeat containing 4.2 [Source:ZFIN;Acc:ZDB-GENE-030131-7997])

HSP 1 Score: 65.4698 bits (158), Expect = 1.428e-10
Identity = 70/270 (25.93%), Postives = 115/270 (42.59%), Query Frame = 1 
Query:  589 GLDFLDFSENLKLYIENRAFDNLKLKHLKLDFIGNLEFS---EDAFQGL-LVASLTIAKSHLQALPYRLIEPLSRELRXXXXXXXXXXXXXXXXESLFRQLTILDLHGNPFICSCNMLWLGVTLKWRQNYYRSNTNSFSEPQFPKCDKPYYLLNQYLYEIPETEFNCRSP-KLDRI-EVQFKSQQSAVLKCAASLESKRAPM-KISWLYLSSKEYVPN-LLPSSKSNEAEIEITQKHYID----------QYFCSVSSAAGNASVKVNFN 1344
            GL+ L+ SEN    ++  +F  LK   LK  +I N   +    +AF  +  +  L +A ++L +LP+ L  PLS                          L  L LH NP+ C C+++WL     W + Y  +N+         +C  P YL  +YL E+ ++ F C +P  LD   ++   +++ A LKC      + APM  + WL       +PN  + +  SN   I +     ++           Y C V++ AGN++     N
Sbjct:  213 GLEELEMSENYFPELKPGSFRGLK--SLKKLWIMNSRITTIERNAFDDVTALVELNLAHNNLSSLPHDLFAPLS-------------------------YLVELHLHHNPWRCDCDVVWLA---WWLREYIPTNSTCCG-----RCHTPAYLRGRYLVEVDQSTFQCSAPFILDAPRDLNISAERVAELKC------RTAPMSSVRWL-------LPNGTVLTHGSNHPRISVLNDGTLNFSNVLPADTGVYTCMVTNMAGNSNASAYLN 434
[Close]
BLAST of Immunoglobulin superfamily member 10 vs. Ensembl Zebrafish
Match: lrrc4.1 (leucine rich repeat containing 4.1 [Source:ZFIN;Acc:ZDB-GENE-041210-129])

HSP 1 Score: 56.9954 bits (136), Expect = 5.431e-8
Identity = 69/273 (25.27%), Postives = 113/273 (41.39%), Query Frame = 1 
Query:  574 FYDVSGLDFLDFSENLKLYIENRAFDNLK-LKHLKL--DFIGNLEFSEDAFQGLL-VASLTIAKSHLQALPYRLIEPLSRELRXXXXXXXXXXXXXXXXESLFRQLTILDLHGNPFICSCNMLWLGVTLKWRQNYYRSNTNSFSEPQFPKCDKPYYLLNQYLYEIPETE---FNCRSPKLDRI--EVQFKSQQSAVLKCAASLESKRAPMKISWLY-----LSSKEYVPNLLPSSKSNEAEIEITQKHYID--QYFCSVSSAAGNASVKVNFN 1344
            F  + GL+ L+ SENL   I+  +F  L  LK L +    IG +E   +AF  L  +  L +A ++L +LP+ L  PL                         + L  L LH NP+ C C+ LWL    +W + Y  +N+         +C  P ++  + L E+   +     C +P +     ++   +++ A LKC  +  S      + WL      L+     P L   +  N+  +  +     D   Y C VS+AAGN++     N
Sbjct:  209 FTPLVGLEELEISENLFPEIKPGSFRGLSSLKKLWIMNSQIGLIE--RNAFDDLASLVELNLAHNNLSSLPHDLYTPL-------------------------KYLVELHLHHNPWNCGCDSLWLA---RWLREYIPTNSTCCG-----RCHSPAHMRGRQLVELDRGDTGAMQCSAPFIADAPRDLNISAERVAELKCRTAAMS-----AVRWLLPNGTILTHASSHPRL---TVLNDGTLNFSNVLAGDTGMYTCMVSNAAGNSNASAYLN 438
[Close]
BLAST of Immunoglobulin superfamily member 10 vs. Ensembl Zebrafish
Match: lrrc4.1 (leucine rich repeat containing 4.1 [Source:ZFIN;Acc:ZDB-GENE-041210-129])

HSP 1 Score: 56.9954 bits (136), Expect = 6.399e-8
Identity = 69/273 (25.27%), Postives = 113/273 (41.39%), Query Frame = 1 
Query:  574 FYDVSGLDFLDFSENLKLYIENRAFDNLK-LKHLKL--DFIGNLEFSEDAFQGLL-VASLTIAKSHLQALPYRLIEPLSRELRXXXXXXXXXXXXXXXXESLFRQLTILDLHGNPFICSCNMLWLGVTLKWRQNYYRSNTNSFSEPQFPKCDKPYYLLNQYLYEIPETE---FNCRSPKLDRI--EVQFKSQQSAVLKCAASLESKRAPMKISWLY-----LSSKEYVPNLLPSSKSNEAEIEITQKHYID--QYFCSVSSAAGNASVKVNFN 1344
            F  + GL+ L+ SENL   I+  +F  L  LK L +    IG +E   +AF  L  +  L +A ++L +LP+ L  PL                         + L  L LH NP+ C C+ LWL    +W + Y  +N+         +C  P ++  + L E+   +     C +P +     ++   +++ A LKC  +  S      + WL      L+     P L   +  N+  +  +     D   Y C VS+AAGN++     N
Sbjct:  213 FTPLVGLEELEISENLFPEIKPGSFRGLSSLKKLWIMNSQIGLIE--RNAFDDLASLVELNLAHNNLSSLPHDLYTPL-------------------------KYLVELHLHHNPWNCGCDSLWLA---RWLREYIPTNSTCCG-----RCHSPAHMRGRQLVELDRGDTGAMQCSAPFIADAPRDLNISAERVAELKCRTAAMS-----AVRWLLPNGTILTHASSHPRL---TVLNDGTLNFSNVLAGDTGMYTCMVSNAAGNSNASAYLN 442
[Close]
BLAST of Immunoglobulin superfamily member 10 vs. Ensembl Zebrafish
Match: lrrc4.1 (leucine rich repeat containing 4.1 [Source:ZFIN;Acc:ZDB-GENE-041210-129])

HSP 1 Score: 56.6102 bits (135), Expect = 7.591e-8
Identity = 69/273 (25.27%), Postives = 113/273 (41.39%), Query Frame = 1 
Query:  574 FYDVSGLDFLDFSENLKLYIENRAFDNLK-LKHLKL--DFIGNLEFSEDAFQGLL-VASLTIAKSHLQALPYRLIEPLSRELRXXXXXXXXXXXXXXXXESLFRQLTILDLHGNPFICSCNMLWLGVTLKWRQNYYRSNTNSFSEPQFPKCDKPYYLLNQYLYEIPETE---FNCRSPKLDRI--EVQFKSQQSAVLKCAASLESKRAPMKISWLY-----LSSKEYVPNLLPSSKSNEAEIEITQKHYID--QYFCSVSSAAGNASVKVNFN 1344
            F  + GL+ L+ SENL   I+  +F  L  LK L +    IG +E   +AF  L  +  L +A ++L +LP+ L  PL                         + L  L LH NP+ C C+ LWL    +W + Y  +N+         +C  P ++  + L E+   +     C +P +     ++   +++ A LKC  +  S      + WL      L+     P L   +  N+  +  +     D   Y C VS+AAGN++     N
Sbjct:  209 FTPLVGLEELEISENLFPEIKPGSFRGLSSLKKLWIMNSQIGLIE--RNAFDDLASLVELNLAHNNLSSLPHDLYTPL-------------------------KYLVELHLHHNPWNCGCDSLWLA---RWLREYIPTNSTCCG-----RCHSPAHMRGRQLVELDRGDTGAMQCSAPFIADAPRDLNISAERVAELKCRTAAMS-----AVRWLLPNGTILTHASSHPRL---TVLNDGTLNFSNVLAGDTGMYTCMVSNAAGNSNASAYLN 438
[Close]
BLAST of Immunoglobulin superfamily member 10 vs. Ensembl Zebrafish
Match: lrrc4.1 (leucine rich repeat containing 4.1 [Source:ZFIN;Acc:ZDB-GENE-041210-129])

HSP 1 Score: 56.6102 bits (135), Expect = 7.838e-8
Identity = 69/273 (25.27%), Postives = 113/273 (41.39%), Query Frame = 1 
Query:  574 FYDVSGLDFLDFSENLKLYIENRAFDNLK-LKHLKL--DFIGNLEFSEDAFQGLL-VASLTIAKSHLQALPYRLIEPLSRELRXXXXXXXXXXXXXXXXESLFRQLTILDLHGNPFICSCNMLWLGVTLKWRQNYYRSNTNSFSEPQFPKCDKPYYLLNQYLYEIPETE---FNCRSPKLDRI--EVQFKSQQSAVLKCAASLESKRAPMKISWLY-----LSSKEYVPNLLPSSKSNEAEIEITQKHYID--QYFCSVSSAAGNASVKVNFN 1344
            F  + GL+ L+ SENL   I+  +F  L  LK L +    IG +E   +AF  L  +  L +A ++L +LP+ L  PL                         + L  L LH NP+ C C+ LWL    +W + Y  +N+         +C  P ++  + L E+   +     C +P +     ++   +++ A LKC  +  S      + WL      L+     P L   +  N+  +  +     D   Y C VS+AAGN++     N
Sbjct:  209 FTPLVGLEELEISENLFPEIKPGSFRGLSSLKKLWIMNSQIGLIE--RNAFDDLASLVELNLAHNNLSSLPHDLYTPL-------------------------KYLVELHLHHNPWNCGCDSLWLA---RWLREYIPTNSTCCG-----RCHSPAHMRGRQLVELDRGDTGAMQCSAPFIADAPRDLNISAERVAELKCRTAAMS-----AVRWLLPNGTILTHASSHPRL---TVLNDGTLNFSNVLAGDTGMYTCMVSNAAGNSNASAYLN 438
[Close]
BLAST of Immunoglobulin superfamily member 10 vs. Ensembl Xenopus
Match: ENSXETT00000007893.1 (leucine rich repeat and fibronectin type III domain containing 4 [Source:NCBI gene;Acc:101734445])

HSP 1 Score: 61.6178 bits (148), Expect = 3.515e-9
Identity = 50/180 (27.78%), Postives = 78/180 (43.33%), Query Frame = 1 
Query:  883 ILDLHGNPFICSCNMLWLGVTLKWRQNYYRSNTNSFSEPQFPKCDKPYYLLNQYLYEIPETEFNCRSPKLDRIEVQF--KSQQSAVLKCAASLESKRAPMKISWLYLSSKEYVPN--LLPSSKSNEAEIEITQKHYIDQYFCSVSSAAGNASVKVNF--------NWPTVTNIRQRPNNS 1386
            +L+  GNPF C+C +LWL   ++              E     C  P  L  +Y + IPE EF C  P + R   Q      Q A LKC A  + +  P+ I W+    K  +PN     S ++   +I +T       Y C   +AAG ++ +V+         N  +++ +RQ P +S
Sbjct:  236 VLNFGGNPFHCNCELLWLRRLVR--------------EDDMETCASPSQLAGRYFWSIPEEEFTCEPPLITRHTHQLWVLEGQRATLKCRAIGDPE--PV-IHWVSPDDK-IMPNSSRTASYRNGTLDILVTTIRDDGSYTCIAINAAGESTAQVDLKMIPLPHRNNGSISVLRQDPGSS 397
[Close]
BLAST of Immunoglobulin superfamily member 10 vs. Ensembl Xenopus
Match: lrrc4 (leucine rich repeat containing 4 [Source:NCBI gene;Acc:100493671])

HSP 1 Score: 56.225 bits (134), Expect = 1.645e-7
Identity = 63/266 (23.68%), Postives = 109/266 (40.98%), Query Frame = 1 
Query:  589 GLDFLDFSENLKLYIENRAFDNLKLKHLKLDFIGNLEFS---EDAFQGLL-VASLTIAKSHLQALPYRLIEPLSRELRXXXXXXXXXXXXXXXXESLFRQLTILDLHGNPFICSCNMLWLGVTLKWRQNYYRSNTNSFSEPQFPKCDKPYYLLNQYLYEIPETEFNCRSPKLDRI--EVQFKSQQSAVLKCAASLESKRAPMKISWLYLSSK--EYVPNLLPSSKSNEAEIEITQKHYIDQ--YFCSVSSAAGNASVKVNFNWPTV 1356
            GL+ L+ S N    I+  +F  L+   LK  +I N + +    +AF  L  +  L +A +++ +LP+ L  PL                         + L  L LH NP+ C C++LWL     W + Y  +N+         +C  P ++  +Y+ E+  + F C +P +     ++     + A LKC  S  S      + WL  +     +  N    +  N+  +  +Q    D   Y C V++ AGN++     N  T 
Sbjct:  213 GLEELEISGNNFPEIKPGSFHGLR--SLKKLWIMNSQINTIERNAFDDLTSLVELNLAHNNVTSLPHDLFAPL-------------------------KYLVELHLHHNPWDCDCDVLWLS---WWLREYIPTNSTCCG-----RCHSPPHMRGKYVVEVDHSMFQCSAPFIMDAPRDLNISEGRMAELKCRTSAMS-----SVRWLLPNGTVLTHASNHPRITILNDGTLNFSQVLLTDTGVYTCMVTNVAGNSNASAYLNVSTA 438
[Close]
BLAST of Immunoglobulin superfamily member 10 vs. Ensembl Mouse
Match: Lrrc4 (leucine rich repeat containing 4 [Source:MGI Symbol;Acc:MGI:2182081])

HSP 1 Score: 67.3958 bits (163), Expect = 4.293e-11
Identity = 69/266 (25.94%), Postives = 110/266 (41.35%), Query Frame = 1 
Query:  589 GLDFLDFSENLKLYIENRAFDNLKLKHLKLDFIGNLEFS---EDAFQGLL-VASLTIAKSHLQALPYRLIEPLSRELRXXXXXXXXXXXXXXXXESLFRQLTILDLHGNPFICSCNMLWLGVTLKWRQNYYRSNTNSFSEPQFPKCDKPYYLLNQYLYEIPETEFNCRSPKLDRI--EVQFKSQQSAVLKCAASLESKRAPM-KISWL-----YLSSKEYVPNLLPSSKSNEAEIEITQKHYIDQ--YFCSVSSAAGNASVKVNFN 1344
            GL+ L+ S N    I   +F  L    LK  ++ N + S    +AF GL  +  L +A ++L +LP+ L  PL                         R L  L LH NP+ C C++LWL     W + Y  +N+         +C  P ++  +YL E+ +  F C +P +     ++     + A LKC      +  PM  + WL      LS     P +   S  N+  +  ++   ID   Y C V++ AGN++     N
Sbjct:  218 GLEELEMSGNHFPEIRPGSFHGLS--SLKKLWVMNSQVSLIERNAFDGLASLVELNLAHNNLSSLPHDLFTPL-------------------------RYLVELHLHHNPWNCDCDILWLA---WWLREYIPTNSTCCG-----RCHAPMHMRGRYLVEVDQAAFQCSAPFIMDAPRDLNISEDRMAELKC------RTPPMSSVKWLLPNGTVLSHASRHPRI---SVLNDGTLNFSRVLLIDTGVYTCMVTNVAGNSNASAYLN 439
[Close]
BLAST of Immunoglobulin superfamily member 10 vs. Ensembl Mouse
Match: Lrfn5 (leucine rich repeat and fibronectin type III domain containing 5 [Source:MGI Symbol;Acc:MGI:2144814])

HSP 1 Score: 52.7582 bits (125), Expect = 1.565e-6
Identity = 94/398 (23.62%), Postives = 149/398 (37.44%), Query Frame = 1 
Query:  286 FILPLFMYDSLTAVFIKPCPNVC-----TPCLEHAITCENGGLDGIPTELYEETTRVILVGHKFSQTFLSRQNFSKFTKPKYSIEXXXXXXXXXXXXXXXTFYDVSGLDFLDFSENLKLYIENRAFDNL-KLKHLKLDFIGNLEFSEDAFQGLL-VASLTIAKSHLQALPYRLIEPL---------------------SRELRXXXXXXXXXXXXXXXXESLFRQLTIL-------------DLHGNPFICSCNMLWLGVTLKWRQNYYRSNTNSFSEPQFPKCDKPYYLLNQYLYEIPETEFNCRSPKLDR--IEVQFKSQQSAVLKCAASLESKRAPMKISWLYLSSKEYVPNLLPSS--KSNEAEIEITQKHYIDQYFCSVSSAAGNASVKVNFN 1344
            F+  LF+     AV  + CP  C     +P L  A  C   GL  +P  +   T  + L  +    T + R++F+  T    S+  L++ R+ I  I    F D+  L  L  + N    I N  F  L  L HL L+       S  AF  +  +  L ++ ++L+ +P+  +E +                     S   +   L            + LF++  +L                GNP  C+C +LWL       +   R       E     C  P  L  +Y + IPE EF C  P + R   E++    Q A L+C A  + + A   I W+    K  + N   S    +   +I IT       + C  S+ AG A+  V+ +
Sbjct:    4 FLFYLFLIG--IAVRAQICPKRCVCQILSPNL--ATLCAKKGLLFVPPNIDRRTVELRLADNFV--TNIKRKDFANMT----SLVDLTLSRNTISFITPHAFADLRNLRALHLNSNRLTKITNDMFSGLSNLHHLILNNNQLTLISSTAFDDVFALEELDLSYNNLETIPWDAVEKMVSLHTLSLDHNMIDNIPKGTFSHLHKMTRLDVTSNKLQKLPPDPLFQRAQVLATSGIISPSTFALSFGGNPLHCNCELLWL-------RRLSR-------EDDLETCASPALLTGRYFWSIPEEEFLCEPPLITRHTHEMRVLEGQRATLRCKARGDPEPA---IHWISPEGK-LISNATRSLVYDNGTLDILITTVKDTGAFTCIASNPAGEATQTVDLH 373
[Close]
BLAST of Immunoglobulin superfamily member 10 vs. Ensembl Mouse
Match: Lrfn5 (leucine rich repeat and fibronectin type III domain containing 5 [Source:MGI Symbol;Acc:MGI:2144814])

HSP 1 Score: 52.373 bits (124), Expect = 1.848e-6
Identity = 44/157 (28.03%), Postives = 64/157 (40.76%), Query Frame = 1 
Query:  886 LDLHGNPFICSCNMLWLGVTLKWRQNYYRSNTNSFSEPQFPKCDKPYYLLNQYLYEIPETEFNCRSPKLDR--IEVQFKSQQSAVLKCAASLESKRAPMKISWLYLSSKEYVPNLLPSS--KSNEAEIEITQKHYIDQYFCSVSSAAGNASVKVNFN 1344
            L   GNP  C+C +LWL       +   R       E     C  P  L  +Y + IPE EF C  P + R   E++    Q A L+C A  + + A   I W+    K  + N   S    +   +I IT       + C  S+ AG A+  V+ +
Sbjct:  235 LSFGGNPLHCNCELLWL-------RRLSR-------EDDLETCASPALLTGRYFWSIPEEEFLCEPPLITRHTHEMRVLEGQRATLRCKARGDPEPA---IHWISPEGK-LISNATRSLVYDNGTLDILITTVKDTGAFTCIASNPAGEATQTVDLH 373
[Close]
BLAST of Immunoglobulin superfamily member 10 vs. Ensembl Mouse
Match: Lrrc4b (leucine rich repeat containing 4B [Source:MGI Symbol;Acc:MGI:3027390])

HSP 1 Score: 52.373 bits (124), Expect = 1.886e-6
Identity = 61/266 (22.93%), Postives = 104/266 (39.10%), Query Frame = 1 
Query:  592 LDFLDFSENLKLYIENRAFDNL-KLKHLKLDFIGNLEFSEDAFQGLL-VASLTIAKSHLQALPYRLIEPLSRELRXXXXXXXXXXXXXXXXESLFRQLTILDLHGNPFICSCNMLWLGVTLKWRQNYYRSNTNSFSEPQFPKCDKPYYLLNQYLYEIPETEFNCRSPKLDR--IEVQFKSQQSAVLKCAASLESKRAPMKISWLYLSSKEYVPN-LLPSSKSNEAEIEITQKHYID----------QYFCSVSSAAGNASVKVNFN 1344
            L+ L+ S N    I   +F  L  L+ L L          +AF  L  +  L ++ ++L +LP+ L  PL R                         L  + L+ NP+ C+C++LWL     W +    SNT   +     +C  P  L  +Y+ E+ ++ F C +P +     ++      +A LKC     +  +   ++WL        PN  L +  S    I +     ++          QY C V+++AGN +     N
Sbjct:  233 LEELELSGNRLDLIRPGSFQGLTSLRKLWLMHAQVATIERNAFDDLKSLEELNLSHNNLMSLPHDLFTPLHR-------------------------LERVHLNHNPWHCNCDVLWLS---WWLKETVPSNTTCCA-----RCHAPAGLKGRYIGELDQSHFTCYAPVIVEPPTDLNVTEGMAAELKC----RTGTSMTSVNWL-------TPNGTLMTHGSYRVRISVLHDGTLNFTNVTVQDTGQYTCMVTNSAGNTTASATLN 454
[Close]
BLAST of Immunoglobulin superfamily member 10 vs. Ensembl Mouse
Match: Lrrc4c (leucine rich repeat containing 4C [Source:MGI Symbol;Acc:MGI:2442636])

HSP 1 Score: 52.373 bits (124), Expect = 1.986e-6
Identity = 66/267 (24.72%), Postives = 106/267 (39.70%), Query Frame = 1 
Query:  592 LDFLDFSENLKLYIENRAFDNLKLKHL-KLDFI-GNLEFSE-DAFQGLL-VASLTIAKSHLQALPYRLIEPLSRELRXXXXXXXXXXXXXXXXESLFRQLTILDLHGNPFICSCNMLWLGVTLKWRQNYYRSNTNSFSEPQFPKCDKPYYLLNQYLYEIPETEFNCRSPKLDR--IEVQFKSQQSAVLKCAASLESKRAPMKISWL-----YLSSKEYVPNLLPSSKSNEAEIEITQKHYIDQYFCSVSSAAGNASVKVNFNWPTVT 1359
            LD LD S N    I   +F  L   HL KL  I   ++  E +AF  L  +  + +A ++L  LP+ L  PL                           L  + LH NP+ C+C++LWL     W ++   SNT   +     +C+ P  L  +Y+ E+ +  F C +P +     ++      +A LKC AS     +   +SW+      ++   Y   +   S        +T +     Y C VS++ GN +     N    T
Sbjct:  221 LDELDLSGNHLSAIRPGSFQGLM--HLQKLWMIQSQIQVIERNAFDNLQSLVEINLAHNNLTLLPHDLFTPL-------------------------HHLERIHLHHNPWNCNCDILWLS---WWIRDMAPSNTACCA-----RCNTPPNLKGRYIGELDQNYFTCYAPVIVEPPADLNVTEGMAAELKCRAS----TSLTSVSWITPNGTVMTHGAYKVRIAVLSDGTLNFTNVTVQD-TGMYTCMVSNSVGNTTASATLNVTAAT 447
[Close]
BLAST of Immunoglobulin superfamily member 10 vs. UniProt/SwissProt
Match: sp|Q99PH1|LRRC4_MOUSE (Leucine-rich repeat-containing protein 4 OS=Mus musculus OX=10090 GN=Lrrc4 PE=1 SV=2)

HSP 1 Score: 67.3958 bits (163), Expect = 3.003e-10
Identity = 69/266 (25.94%), Postives = 110/266 (41.35%), Query Frame = 1 
Query:  589 GLDFLDFSENLKLYIENRAFDNLKLKHLKLDFIGNLEFS---EDAFQGLL-VASLTIAKSHLQALPYRLIEPLSRELRXXXXXXXXXXXXXXXXESLFRQLTILDLHGNPFICSCNMLWLGVTLKWRQNYYRSNTNSFSEPQFPKCDKPYYLLNQYLYEIPETEFNCRSPKLDRI--EVQFKSQQSAVLKCAASLESKRAPM-KISWL-----YLSSKEYVPNLLPSSKSNEAEIEITQKHYIDQ--YFCSVSSAAGNASVKVNFN 1344
            GL+ L+ S N    I   +F  L    LK  ++ N + S    +AF GL  +  L +A ++L +LP+ L  PL                         R L  L LH NP+ C C++LWL     W + Y  +N+         +C  P ++  +YL E+ +  F C +P +     ++     + A LKC      +  PM  + WL      LS     P +   S  N+  +  ++   ID   Y C V++ AGN++     N
Sbjct:  218 GLEELEMSGNHFPEIRPGSFHGLS--SLKKLWVMNSQVSLIERNAFDGLASLVELNLAHNNLSSLPHDLFTPL-------------------------RYLVELHLHHNPWNCDCDILWLA---WWLREYIPTNSTCCG-----RCHAPMHMRGRYLVEVDQAAFQCSAPFIMDAPRDLNISEDRMAELKC------RTPPMSSVKWLLPNGTVLSHASRHPRI---SVLNDGTLNFSRVLLIDTGVYTCMVTNVAGNSNASAYLN 439
[Close]
BLAST of Immunoglobulin superfamily member 10 vs. UniProt/SwissProt
Match: sp|Q45R42|LRRC4_RAT (Leucine-rich repeat-containing protein 4 OS=Rattus norvegicus OX=10116 GN=Lrrc4 PE=1 SV=1)

HSP 1 Score: 67.0106 bits (162), Expect = 3.389e-10
Identity = 69/266 (25.94%), Postives = 110/266 (41.35%), Query Frame = 1 
Query:  589 GLDFLDFSENLKLYIENRAFDNLKLKHLKLDFIGNLEFS---EDAFQGLL-VASLTIAKSHLQALPYRLIEPLSRELRXXXXXXXXXXXXXXXXESLFRQLTILDLHGNPFICSCNMLWLGVTLKWRQNYYRSNTNSFSEPQFPKCDKPYYLLNQYLYEIPETEFNCRSPKLDRI--EVQFKSQQSAVLKCAASLESKRAPM-KISWL-----YLSSKEYVPNLLPSSKSNEAEIEITQKHYIDQ--YFCSVSSAAGNASVKVNFN 1344
            GL+ L+ S N    I   +F  L    LK  ++ N + S    +AF GL  +  L +A ++L +LP+ L  PL                         R L  L LH NP+ C C++LWL     W + Y  +N+         +C  P ++  +YL E+ +  F C +P +     ++     + A LKC      +  PM  + WL      LS     P +   S  N+  +  ++   ID   Y C V++ AGN++     N
Sbjct:  218 GLEELEMSGNHFPEIRPGSFHGLS--SLKKLWVMNSQVSLIERNAFDGLASLVELNLAHNNLSSLPHDLFTPL-------------------------RYLVELHLHHNPWNCDCDILWLA---WWLREYIPTNSTCCG-----RCHAPMHMRGRYLVEVDQASFQCSAPFIMDAPRDLNISEDRMAELKC------RTPPMSSVKWLLPNGTVLSHASRHPRI---SVLNDGTLNFSRVLLIDTGVYTCMVTNVAGNSNASAYLN 439
[Close]
BLAST of Immunoglobulin superfamily member 10 vs. UniProt/SwissProt
Match: sp|Q9HBW1|LRRC4_HUMAN (Leucine-rich repeat-containing protein 4 OS=Homo sapiens OX=9606 GN=LRRC4 PE=1 SV=2)

HSP 1 Score: 63.929 bits (154), Expect = 3.090e-9
Identity = 68/266 (25.56%), Postives = 108/266 (40.60%), Query Frame = 1 
Query:  589 GLDFLDFSENLKLYIENRAFDNLKLKHLKLDFIGNLEFS---EDAFQGLL-VASLTIAKSHLQALPYRLIEPLSRELRXXXXXXXXXXXXXXXXESLFRQLTILDLHGNPFICSCNMLWLGVTLKWRQNYYRSNTNSFSEPQFPKCDKPYYLLNQYLYEIPETEFNCRSPKLDRI--EVQFKSQQSAVLKCAASLESKRAPM-KISWL-----YLSSKEYVPNLLPSSKSNEAEIEITQKHYIDQ--YFCSVSSAAGNASVKVNFN 1344
            GL+ L+ S N    I   +F  L    LK  ++ N + S    +AF GL  +  L +A ++L +LP+ L  PL                         R L  L LH NP+ C C++LWL     W + Y  +N+         +C  P ++  +YL E+ +  F C +P +     ++     + A LKC      +  PM  + WL      LS     P +   S  N+  +  +     D   Y C V++ AGN++     N
Sbjct:  219 GLEELEMSGNHFPEIRPGSFHGLS--SLKKLWVMNSQVSLIERNAFDGLASLVELNLAHNNLSSLPHDLFTPL-------------------------RYLVELHLHHNPWNCDCDILWLA---WWLREYIPTNSTCCG-----RCHAPMHMRGRYLVEVDQASFQCSAPFIMDAPRDLNISEGRMAELKC------RTPPMSSVKWLLPNGTVLSHASRHPRI---SVLNDGTLNFSHVLLSDTGVYTCMVTNVAGNSNASAYLN 440
[Close]
BLAST of Immunoglobulin superfamily member 10 vs. UniProt/SwissProt
Match: sp|Q8N135|LGI4_HUMAN (Leucine-rich repeat LGI family member 4 OS=Homo sapiens OX=9606 GN=LGI4 PE=1 SV=1)

HSP 1 Score: 54.299 bits (129), Expect = 2.480e-6
Identity = 51/178 (28.65%), Postives = 73/178 (41.01%), Query Frame = 1 
Query:  571 TFYDVSGLDFLDFSENLKLYIENRAFDNLKLKHLKLDFIGNLEF---SEDAFQGLL-VASLTIAKSHLQALPYRLIEPLSRELRXXXXXXXXXXXXXXXXESLFRQLTILDLHGNPFICSCNMLWLGVTLKWRQNYYRSNTNSFSEPQFPKCDKPYYLLNQYLYEIPETEFNCRSPKL 1092
            +F  +  L  L F+ N    IE+ AF  L   HL+  FI + E    S++A +GL  +  L++A +HL+ LP  L   L                           LT +DL GNPF C C +LWL   L+W      S            C  P  L +  L+ +    F CR+ +L
Sbjct:   71 SFLRIPSLHLLLFTSNSFSVIEDDAFAGLS--HLQYLFIEDNEIGSISKNALRGLRSLTHLSLANNHLETLPRFLFRGLD-------------------------TLTHVDLRGNPFQCDCRVLWL---LQWMPTVNASVGTG-------ACAGPASLSHMQLHHLDPKTFKCRAIEL 211
[Close]
BLAST of Immunoglobulin superfamily member 10 vs. TrEMBL
Match: A0A5P8I4L0 (PXDN-like protein OS=Schmidtea mediterranea OX=79327 PE=2 SV=1)

HSP 1 Score: 172.94 bits (437), Expect = 4.606e-43
Identity = 143/473 (30.23%), Postives = 246/473 (52.01%), Query Frame = 1 
Query:  274 IRVSFILPLFMYD---SLTAVFIKPCPNVC--TPCLEHAITCENGGLDGIPTELYEETTRVILVGHKFSQTFLSRQNFSKFTKPKYSIEXXXXXXXXXXXXXXXTFYDVSGLDFLDFSENLKLYIENRAFDNLKLKHLKLDFIGNLEFSEDAFQGLLVASLTIAKSHLQALPYRLIEPLSRELRXXXXXXXXXXXXXXXXESLFRQLTILDLHGNPFICSCNMLWLGVTLKWRQNYYRSNTNSFSEPQFPKCDKPYYLLNQYLYEIPETEFNCRSPKLDRIEVQFKSQQSAVLKCAASLESKRAPMKISWLYLSSKEYVPNLLPSSKSNEAEIEITQKHYIDQYFCSVSSAAGNASVKVNFNWPT--VTNIRQRPNN---SIDEYFVTKPTWKTNYYQENYFFREQYTLLEXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXEQLKKSGHVTYETGFYSDSQTYDIPQYSSS 1662
            +++ F+LP+ ++    + T+    PCP+VC    C    + C +GGL  IP  L+++T ++I+   +FS   L+  NFS +  P Y IE+++++   +  I S  F  ++ L  LD S NL   I    F  L L+ L+LD    ++F   +F+GL VA L++   +L  L + +   +S  L+ L L+NNKL  +  +F  LF  L  L ++ NPF C+CN+ WL   L  R+      ++S   P   +C+ P  +  + + ++   +F+C SP+L  I+V   S  SA L C +  ++  +P  + W+      YVP +    K   A + + +K  ID+Y C + +     +V ++ +WP   V N  Q  N    S ++     P   +  +  + F+ +Q+TLLE++G ++GTF IT+++F+ IY+       +      KK  +++YET   SDSQTYDIP  ++ 
Sbjct:    1 MKIPFLLPMLLFILFLAKTSAHFNPCPSVCHEMACQTGVLACTDGGLLQIPPVLHQKTHKIIVSNQRFSSPHLTYSNFSNYGPPNYKIEKIALQFCELVSIASNCFSHLTDLRVLDLSHNLLGEIPPDTFKALHLQFLRLDDNKMIQFHRFSFRGLNVAELSLFDCNLTELDFEVFSEISERLKKLILTNNKLNVIDKRFRILFENLPDLQINENPFNCTCNLRWLNSVLVSRKKAINL-SSSKRIPNQAQCNYPDRVKGKQIADLDLKDFDCDSPRLKLIDVFMTSTSSAKLTCISEPKAHSSP-DVIWMTEHKNTYVPEIQSIEK---ASLSVLRKSRIDKYKCVIKNNNDYVTVVISIHWPVKRVNNASQSLNTLGVSPNDMIPYLPNANSTLHVRSVFYEKQFTLLEMIGGVVGTFTITMILFLCIYRHLAMTMKRND----KKKWYLSYETAIGSDSQTYDIPNNTAG 464
[Close]
BLAST of Immunoglobulin superfamily member 10 vs. TrEMBL
Match: I1ZIL5 (Slit-2 OS=Schmidtea mediterranea OX=79327 PE=2 SV=1)

HSP 1 Score: 137.502 bits (345), Expect = 9.720e-31
Identity = 147/463 (31.75%), Postives = 236/463 (50.97%), Query Frame = 1 
Query:  340 CPNVCT--PCLEHAITCENGGLDGIPTELYEETTRVILVGHKFSQTFLSRQNFSKFTKPKYSIEXXXXXXXXXXXXXXXTFYDVSGLDFLDFSENLKLYIENRAFDNLKLKHLKLDFIGNLEFSEDAFQGLLVASLTIAKSHLQALPYRLIEPLSRELRXXXXXXXXXXXXXXXXESLFRQLTILDLHGNPFICSCNMLWLGVTLKWRQNYYRSNT--NSFSEPQFPKCDKPYYLLNQYLYEIPETEFNCRSPKLDRIEVQFKSQQSAVLKCAASLESKRAPMKISWLYLSSKEYVPNLLP--------SSKSNEAEIEITQKHYIDQYFCSVSSAAGNASVKVNFNWPT-----VTNIRQRPNNSIDEYFVTKPTWKTNYYQE-------NYFFREQYTLLEXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXEQLKKSGHVTYETGFYSDSQTYDIPQYS 1656
            CP +C    C    + CE  GL  IP        +VIL    F    L+  N S++   +  +++L+I   ++  I S+ F  +  L  LD S N  L+I    F +L LK L LD   NL+ ++D+F+GL+V SL++   HL+ L +  I+ +S  L +L L++N+L  LS+ F+ LFR L  L+L  N F CSC + WL +TL+ R    R N+  +S      P C+ P  L    +  +    F C+ PKL RI+++  S+ +A + C +   S     ++ W       Y  NL P        +S  N+A I +++K   D Y C + +  GNA+V +   WPT     V +    P N+++++ +     K++   +       NY + +QYT +E++ +I GTFIIT++ FIL+Y    ++    + + + K     YE G YS+SQTYD+PQ S
Sbjct:   35 CPELCNQGACKLTMLLCETPGLLQIPMNPPRGIQKVILSNQNFLYPRLTYTNLSRYGSEEIILKKLTISNCSLTSIESEAFSHLIYLQELDLSSNRLLFIYPNTFKSLSLKTLVLDSNRNLQLAKDSFRGLVVQSLSMKDCHLKILTHESIKQISGYLTTLNLADNRLEYLSNDFDLLFRGLDNLNLENNLFNCSCQLKWLALTLQTRTK-RRDNSPKHSLLRLTNPVCEYPKNLKGSSIENLSIVSFQCQIPKLQRIDIKVTSEITAEISCISDDMSNS---QVKW------RYRYNLSPLFYRYPDQNSGVNQASIIVSKKSEFDFYSCLIINENGNATVDIKIKWPTLNKEYVESPINSPPNTVNQFNLRNNITKSSVILKEFDKLHVNYLWIKQYTFIEMVLAICGTFIITLVTFILLYVVINYRRKNSRSKNILKG----YEVGVYSESQTYDVPQMS 483
[Close]
BLAST of Immunoglobulin superfamily member 10 vs. TrEMBL
Match: R7V5M3 (Ig-like domain-containing protein OS=Capitella teleta OX=283909 GN=CAPTEDRAFT_190342 PE=4 SV=1)

HSP 1 Score: 134.42 bits (337), Expect = 1.911e-29
Identity = 104/345 (30.14%), Postives = 171/345 (49.57%), Query Frame = 1 
Query:  340 CPNVCTPCLEHAIT-CENGGLDGIPTELYEETTRVILVGHKFSQTFLSRQNFSKFTKPKYSIEXXXXXXXXXXXXXXXTFYDVSGLDFLDFSENLKLYIENRAFDNLKLKHLKLDFIGNLEFSEDAFQGLLVASLTIAKSHLQALPYRLIEPLSRELRXXXXXXXXXXXXXXXXESLFRQLTILDLHGNPFICSCNMLWLGVTLKWRQNYYRSNTNSFSEPQFPKCDKPYYLLNQYLYEIPETEFNCRSPKLDRIEVQFKSQQSAVLKCAASLESKRAPMKISWLYLSSK--EYVPNLLPSSKSNEAEIEITQKHYIDQ-----YFCSVSSAAGNASVKVNFNWP 1350
            CP+VC   +   I  C   GL  IPT +  +T ++ L G+ F  T L R NFS+++    S+E L +    I+ I   TF D+S L++LD S N    +++  F  L+L+HL L+   ++     A +GL  + L +    L  L   ++ PL+  LR L+L  N+L  L  +   LF  L+ L L  NP  C+C +LWL       + +Y  + + F     P C  P  L  ++  E+  T+F C++P  + I+  F S Q   LKC A+ +   AP  + W+  + +  +Y+      ++ NE  + +T+    DQ     Y C  ++ AGN ++ +N +WP
Sbjct:   61 CPHVCFCNVNSKIVYCSRRGLPAIPTSIPRDTLQLNLNGNVFQSTGLERSNFSRWS----SLEHLYMSECGIESIAVDTFRDLSSLEWLDISNNRIKIVQDYTFRGLQLQHLFLNGNRHIGLQPKAMEGLTTSGLYLHDCSLSRLHPEVLTPLNHTLRYLWLHGNELDRLERRLSPLFSSLSHLRLGSNPLHCNCELLWL-------KEFYDRHGDKFKGATSPSCLTPQRLRGKFFNEMAMTDFRCQAPVFNNIDALFDSFQGR-LKCTATGDP--AP-TLYWIQPNGRTTKYIAPPDEDARKNEGLLTLTKPAGSDQELAGMYICVANNEAGNVTLTINVSWP 390
[Close]
BLAST of Immunoglobulin superfamily member 10 vs. TrEMBL
Match: A0A068YC11 (Variable lymphocyte receptor OS=Echinococcus multilocularis OX=6211 GN=EmuJ_000739800 PE=4 SV=1)

HSP 1 Score: 127.102 bits (318), Expect = 9.548e-27
Identity = 124/454 (27.31%), Postives = 210/454 (46.26%), Query Frame = 1 
Query:  286 FILPLFMYDSLTAVFIKPCP-------NVCTPCLEHAITCENGGL-DGIPTELYEETTRVILVGHKFSQTFLSRQNFSKFTKPKYSIEXXXXXXXXXXXXXXXTFYDVSGLDFLDFSENLKLYIENRAFDNLKLKHLKLDFIGNLEFSEDAFQGLLVASLTIAKSHLQALPYRLIEPL--SRELRXXXXXXXXXXXXXXXXESLFRQLTILDLHGNPFICSCNMLWLGVTLKWRQN------YYRSNTNSF---SEPQFPKCDKPYYLLNQYLYEIPETEFNCRSPKLDRIEVQF---KSQQS--------AVLKCAASLESKRAPMKISWLYLSSKEYVPNLLPSSK---SNEAEIEITQKHYIDQ-----------YFCSVSSAAGNASVKVNFNWPT-----------VTNIR--QRPNNSIDEYFVTKPTWKTNYYQENYFFREQYTLLE 1476
            F+L  F+Y S+  + I+           +C  C   +I+C+   L   +P  L     +VI+V  +F   FLSRQN S +T P  +I +L+I    ++ I + TF  +S L  LD S+N    I+   F  L+L  L+LD    L    +AF+ L V+SL++    L++L Y + +PL  SR L +L L++N LT+L ++FE  FR L+ L L  NPF+C C ++WL  TL+ ++       + R N +      +   P C+ P +L  +++  +   +F C  P++  +EV F   +  QS         ++KCAA    +   M+++W     +   P  LP  +   S   E+ I+   +              + C      GN S  ++  WP             +N R    P++   +Y      +  +   + YFF +++T+LE
Sbjct:    6 FMLNSFLYLSVALLGIRGGEITADEVCRICEGCTYGSISCQEADLLHMLPNNLPNGIEKVIIVSQRFDSQFLSRQNISSYTLPGVNIHELTIMHCGLRAIEAGTFSGLSSLTKLDLSKNSLSRIQGHTFSGLRLDLLRLDDNQGLTLDSEAFENLTVSSLSMQNCGLRSLSYEVFQPLVQSRSLTTLRLTSNSLTTLDARFEPFFRNLSFLSLARNPFVCDCKLVWLSRTLQRKRRADSDDAFRRLNDDRLLIVPDDDHPVCESPNHLRGKHIVSLSTRDFFCGPPQMRALEVDFSDLRVGQSETFNMTGVVLIKCAAQGSPE---MQLAWFRRDRRGGEPIRLPGLRQVASGVVEVSISHSLFAKNSKSETEDAGQLFTCLGVDTYGNTSADLSLRWPALPLLSPLPSSPTSNNRNPMEPSSGDSKYLNNDKGYFQSDRLDEYFFMKKFTILE 456
[Close]
BLAST of Immunoglobulin superfamily member 10 vs. TrEMBL
Match: A0A2H1CUL7 (Leucine Rich repeat-containing domain protein OS=Fasciola hepatica OX=6192 GN=D915_01256 PE=4 SV=1)

HSP 1 Score: 122.865 bits (307), Expect = 4.659e-26
Identity = 111/399 (27.82%), Postives = 187/399 (46.87%), Query Frame = 1 
Query:  349 VCTPCLEHAITCENGGLDGIPTELYEETTRVILVGHKFSQTFLSRQNFSKFTKPKYSIEXXXXXXXXXXXXXXXTFYDVSGLDFLDFSENLKLYIENRAFDNLKLKHLKLDFIGNLEFSEDAFQGLLVASLTIAKSHLQALPYRLIEPLSRE--LRXXXXXXXXXXXXXXXXESLFRQLTILDLHGNPFICSCNMLWLGVTLKWRQNYYRSNT---NSFSEPQF--------PKCDKPYYLLNQYLYEIPETEFNCRSPKLDRIEV---QFK------------SQQSAV-LKCAASLESKRAPMKISWLYLS--------------SKEYVPNLLPSS--KSNEAEIEITQ-------KH----------YIDQYFCSVSSAAGNASVKVNFNWPTVT 1359
            +C+ C+  +++C+ GGL G+P EL ++   +IL+GH+F  + L+R NF+ +      ++++++R   I+ I+  +F  +  L  LD S+N   +IE   F  L+L +L+LD    L  +  AF    + SL++ +  ++++ Y  + PL R   L +L LS N+L +L ++ E +F +L  L L  NPF C C + WL   L+ RQ   +S     +S   P          P C  P  L  + L  +   +F C  P+L  +EV   ++K            SQ  AV L+C  S   +   MK++W   S                +++  LL S    S+ AEI + Q       KH           ++Q  C  +  +GN S +V   WP ++
Sbjct:    1 MCSGCMAGSLSCQEGGLTGLPDELAKDIQSMILIGHRFEGSALARHNFTSYPHQTKVLQRITLRNCGIERIQPGSFEPIQSLKQLDLSQNQINFIEAGTFAGLRLDYLRLDENHRLHLAPGAFNDASIVSLSMNQCGIESITYEDLAPLLRHHVLTTLHLSGNRLVTLENRMEPVFLELQSLSLDQNPFYCDCRLSWLAEVLQRRQIRRKSRALKQDSIMGPDAPLDSDLPRPTCRAPDRLAGRPLETLTTEDFFCGLPQLKNLEVFIEEYKEAGENQKLVNSVSQPLAVTLRCQVSGSPE---MKLAWYRRSIFSPTVTSQLEFYNELDHLSKLLSSRAVSSDVAEIRLIQPSPSISSKHDPISSKSQSSALEQLVCMATDTSGNISAEVRLQWPPLS 396
[Close]
BLAST of Immunoglobulin superfamily member 10 vs. Ensembl Cavefish
Match: lrrc4.2 (leucine rich repeat containing 4.2 [Source:ZFIN;Acc:ZDB-GENE-030131-7997])

HSP 1 Score: 65.0846 bits (157), Expect = 1.471e-10
Identity = 70/268 (26.12%), Postives = 113/268 (42.16%), Query Frame = 1 
Query:  589 GLDFLDFSENLKLYIENRAFDNLK-LKHLKLDFIGNLEFSEDAFQGL-LVASLTIAKSHLQALPYRLIEPLSRELRXXXXXXXXXXXXXXXXESLFRQLTILDLHGNPFICSCNMLWLGVTLKWRQNYYRSNTNSFSEPQFPKCDKPYYLLNQYLYEIPETEFNCRSP-KLDRI-EVQFKSQQSAVLKCAASLESKRAPM-KISWLYLSSKEYVPN-LLPSSKSNEAEIEITQKHYID----------QYFCSVSSAAGNASVKVNFN 1344
            GL+ L+ SEN    I+  +F  LK LK L +          +AF  +  +  L +A ++L +LP+ L  PLS                          L  L LH NP+ C C+++WL     W + Y  +N+         +C  P +L  +YL E+ +T F C +P  LD   ++   +++ A LKC      + APM  + WL       +PN  + +  SN   I +     ++           Y C V++ AGN++     N
Sbjct:  213 GLEELEMSENYFPEIKPGSFRGLKSLKKLWIMNSRITTMERNAFDDVTALVELNLAHNNLSSLPHDLFAPLS-------------------------YLVELHLHHNPWRCDCDVVWLA---WWLREYIPTNSTCCG-----RCHTPAHLRGRYLVEVDQTTFQCSAPFILDAPRDLNISAERVAELKC------RTAPMSSVRWL-------LPNGTVLTHGSNHPRIYVLNDGTLNFSNVLASDTGVYTCMVTNMAGNSNASAYLN 434
[Close]
BLAST of Immunoglobulin superfamily member 10 vs. Ensembl Cavefish
Match: lrrc4ba (leucine-rich repeat-containing protein 4B-like [Source:NCBI gene;Acc:103034410])

HSP 1 Score: 54.299 bits (129), Expect = 4.036e-7
Identity = 76/298 (25.50%), Postives = 122/298 (40.94%), Query Frame = 1 
Query:  574 FYDVSGLDFLDFSENLKL-YIENRAFDNL-KLKHLKLDFIG--------------NLEFSED--------AFQGL-LVASLTIAKSHLQALPYRLIEPLSRELRXXXXXXXXXXXXXXXXESLFRQLTILD---LHGNPFICSCNMLWLGVTLKWRQNYYRSNTNSFSEPQFPKCDKPYYLLNQYLYEIPETEFNCRSPKLDR--IEVQFKSQQSAVLKCAASLESKRAPMKISWLYLSSKEYVPN-LLPSSKSNEAEIEITQKHYID----------QYFCSVSSAAGNASVKVNFN 1344
            F+ V  L  LD  E  KL YI + AF  L  L++L L   G               LE S +        +FQGL  +  L +  S +  +     +    +L+SL   N    SL S    LF  L  L+   L+ NP++C+C++LWL     W +    SNT   +     +C  P YL  +Y+ E+ ++ F C +P +     ++      +A LKC     +  +   ++W+        PN  L +  S    I +     ++          QY C V+++AGN +     N
Sbjct:  161 FHRVPSLRRLDLGELKKLDYISDAAFVGLINLRYLNLGMCGLKDIPNLTPLVRLEELELSGNRLEIIRPGSFQGLESLRKLWLMHSQMTVIERNAFD----DLKSLEELNLSHNSLHSLPHDLFTPLQKLERVHLNHNPWVCNCDVLWLS---WWLKETVPSNTTCCA-----RCHAPPYLKGKYIGELDQSHFTCYAPVIVEPPTDLNVTEGMAAELKC----RTGTSMTSVNWI-------TPNGTLMTHGSYRVRISVLHDGTLNFTNVTLRDTGQYTCMVTNSAGNTTATAVLN 435
[Close]
BLAST of Immunoglobulin superfamily member 10 vs. Ensembl Cavefish
Match: lrrc4ba (leucine-rich repeat-containing protein 4B-like [Source:NCBI gene;Acc:103034410])

HSP 1 Score: 54.299 bits (129), Expect = 4.036e-7
Identity = 76/298 (25.50%), Postives = 122/298 (40.94%), Query Frame = 1 
Query:  574 FYDVSGLDFLDFSENLKL-YIENRAFDNL-KLKHLKLDFIG--------------NLEFSED--------AFQGL-LVASLTIAKSHLQALPYRLIEPLSRELRXXXXXXXXXXXXXXXXESLFRQLTILD---LHGNPFICSCNMLWLGVTLKWRQNYYRSNTNSFSEPQFPKCDKPYYLLNQYLYEIPETEFNCRSPKLDR--IEVQFKSQQSAVLKCAASLESKRAPMKISWLYLSSKEYVPN-LLPSSKSNEAEIEITQKHYID----------QYFCSVSSAAGNASVKVNFN 1344
            F+ V  L  LD  E  KL YI + AF  L  L++L L   G               LE S +        +FQGL  +  L +  S +  +     +    +L+SL   N    SL S    LF  L  L+   L+ NP++C+C++LWL     W +    SNT   +     +C  P YL  +Y+ E+ ++ F C +P +     ++      +A LKC     +  +   ++W+        PN  L +  S    I +     ++          QY C V+++AGN +     N
Sbjct:  161 FHRVPSLRRLDLGELKKLDYISDAAFVGLINLRYLNLGMCGLKDIPNLTPLVRLEELELSGNRLEIIRPGSFQGLESLRKLWLMHSQMTVIERNAFD----DLKSLEELNLSHNSLHSLPHDLFTPLQKLERVHLNHNPWVCNCDVLWLS---WWLKETVPSNTTCCA-----RCHAPPYLKGKYIGELDQSHFTCYAPVIVEPPTDLNVTEGMAAELKC----RTGTSMTSVNWI-------TPNGTLMTHGSYRVRISVLHDGTLNFTNVTLRDTGQYTCMVTNSAGNTTATAVLN 435
[Close]
BLAST of Immunoglobulin superfamily member 10 vs. Ensembl Cavefish
Match: lrrc4ba (leucine-rich repeat-containing protein 4B-like [Source:NCBI gene;Acc:103034410])

HSP 1 Score: 53.9138 bits (128), Expect = 4.227e-7
Identity = 75/295 (25.42%), Postives = 124/295 (42.03%), Query Frame = 1 
Query:  574 FYDVSGLDFLDFSENLKL-YIENRAFDNL-KLKHLKLDFIG--------------NLEFSED--------AFQGL-LVASLTIAKSHLQALPYRLIEPLSRELRXXXXXXXXXXXXXXXXESLFRQLTILDLHGNPFICSCNMLWLGVTLKWRQNYYRSNTNSFSEPQFPKCDKPYYLLNQYLYEIPETEFNCRSPKLDR--IEVQFKSQQSAVLKCAASLESKRAPMKISWLYLSSKEYVPN-LLPSSKSNEAEIEITQKHYID----------QYFCSVSSAAGNASVKVNFN 1344
            F+ V  L  LD  E  KL YI + AF  L  L++L L   G               LE S +        +FQGL  +  L +  S +  +     + L + L  L LS+N L SL     +  ++L  + L+ NP++C+C++LWL     W +    SNT   +     +C  P YL  +Y+ E+ ++ F C +P +     ++      +A LKC     +  +   ++W+        PN  L +  S    I +     ++          QY C V+++AGN +     N
Sbjct:  148 FHRVPSLRRLDLGELKKLDYISDAAFVGLINLRYLNLGMCGLKDIPNLTPLVRLEELELSGNRLEIIRPGSFQGLESLRKLWLMHSQMTVIERNAFDDL-KSLEELNLSHNSLHSLPHDLFTPLQKLERVHLNHNPWVCNCDVLWLS---WWLKETVPSNTTCCA-----RCHAPPYLKGKYIGELDQSHFTCYAPVIVEPPTDLNVTEGMAAELKC----RTGTSMTSVNWI-------TPNGTLMTHGSYRVRISVLHDGTLNFTNVTLRDTGQYTCMVTNSAGNTTATAVLN 422
[Close]
BLAST of Immunoglobulin superfamily member 10 vs. Ensembl Cavefish
Match: lrrc4ca (leucine-rich repeat-containing protein 4C [Source:NCBI gene;Acc:103046976])

HSP 1 Score: 53.1434 bits (126), Expect = 7.811e-7
Identity = 64/272 (23.53%), Postives = 106/272 (38.97%), Query Frame = 1 
Query:  592 LDFLDFSENLKLYIENRAFDNLK------LKHLKLDFIGNLEFSEDAFQGLLVASLTIAKSHLQALPYRLIEPLSRELRXXXXXXXXXXXXXXXXESLFRQLTILDLHGNPFICSCNMLWLGVTLKWRQNYYRSNTNSFSEPQFPKCDKPYYLLNQYLYEIPETEFNCRSPKLDR--IEVQFKSQQSAVLKCAASLESKRAPMKISWL-----YLSSKEYVPNLLPSSKSNEAEIEITQKHYID--QYFCSVSSAAGNASVKVNFNWPTVTN 1362
            LD L+ S N    I   +F  L       + H ++  I    F  D  Q L+   L +A ++L  LP+ L  PL                           L  + LH NP+ C+C++LWL     W +    +NT+  +     +C  P     +Y+ E+ +  F+C +P +     ++      +A LKC AS     +   +SW+      ++   Y   +   S  N+  +  T     D   Y C VS++AGN +     N  +  N
Sbjct:  222 LDELEMSGNQLSVIRPGSFKGLVHLQKLWMMHAQIQTIERNAF--DDLQSLV--ELNLAHNNLTLLPHDLFTPL-------------------------HHLERVHLHHNPWNCNCDILWLS---WWLKEMVPANTSCCA-----RCSTPTSHKGRYIGELDQNYFHCYAPVIVEPPADLNVTEGMAAELKCRAS-----SLTSVSWITPNGSIMTHGAYKVRI---SVLNDGTLNFTNVTMQDTGTYTCMVSNSAGNTTASATLNVSSTEN 448
[Close]
BLAST of Immunoglobulin superfamily member 10 vs. Ensembl Sea Lamprey
Match: lrfn5a (leucine rich repeat and fibronectin type III domain containing 5a [Source:ZFIN;Acc:ZDB-GENE-080327-17])

HSP 1 Score: 57.3806 bits (137), Expect = 8.624e-9
Identity = 93/393 (23.66%), Postives = 150/393 (38.17%), Query Frame = 1 
Query:  340 CPNVC-----TPCLEHAITCENGGLDGIPTELYEETTRVILVGHKFSQTFLSRQNFSKFTKPKYSIEXXXXXXXXXXXXXXXTFYDVSGLDFLDFSENLKLYIENRAFDNLK-LKHLKLDFIGNLEFSEDAFQGLLVA--SLTIAKSHLQALPYRLIEPL---------------------SRELRXXXXXXXXXXXXXXXXESLFRQLT-------------ILDLHGNPFICSCNMLWLGVTLKWRQNYYRSNTNSFSEPQFPKCDKPYYLLNQYLYEIPETEFNCRSPKLDR--IEVQFKSQQSAVLKCAASLESKRAPMKISWLYLSS--KEYVPNLLPSSKSNEAEIEITQKHYIDQ--YFCSVSSAAGNASVKVNF---NWPTVTNI 1365
            CP  C     +P L  +  C   GL  +P  +   T  + L G  F  T + RQ+F   T     +  L++ R+ I  I    F D+S L FL F  N   +I N++F  L  L+HL +      + S  AF   L++   L +A ++L+ +P+  I+ +                     S   +   L            + LF +L              +L+  GNP  C+C +LWL    +              E     C  P  L+ +Y + IPE EF C  P + R    +     Q A LKC A  +         W++  S  ++ + N   +   +   +EI      D   + C  S+ AG ++  V     + P ++NI
Sbjct:   20 CPTHCICQNLSPSL--STVCAKIGLLFVPHNIDRRTVELRL-GDNFI-TSVRRQDFGNMTL----MVDLTLSRNTISQIAPYAFADLSSLTFLHFDYNRLTHIGNKSFKGLSNLRHLIISNNQLSDISVGAFDDFLMSLEDLDLAYNNLEKVPWEAIQKMTSLHTLSLDHNMIDYIEAGTFSHLHKLARLDMTSNKLQKLPPDPLFTRLQLFANKGIHHTPPLVLNFGGNPLHCNCELLWLRRLTR--------------EDDLETCASPQALVGKYFWSIPEEEFVCEPPLITRHTHRLLVLEGQRATLKCKAIGDPD------PWVHWISPDEKVISNTTRTVVHDNGTLEILVTTTKDDGTFTCIASNPAGESTTFVELSIIHLPHLSNI 384
[Close]
BLAST of Immunoglobulin superfamily member 10 vs. Ensembl Medaka
Match: lrrc4.1 (leucine-rich repeat-containing protein 4 [Source:NCBI gene;Acc:101168588])

HSP 1 Score: 64.6994 bits (156), Expect = 1.800e-10
Identity = 73/292 (25.00%), Postives = 122/292 (41.78%), Query Frame = 1 
Query:  583 VSGLDFLDFSENLKLYIENRAFDNLKLKHLKLDFIGNLEFS---EDAFQGLL-VASLTIAKSHLQALPYRLIEPLSRELRXXXXXXXXXXXXXXXXESLFRQLTILDLHGNPFICSCNMLWLGVTLKWRQNYYRSNTNSFSEPQFPKCDKPYYLLNQYLYEIPETE---FNCRSPKLDRI--EVQFKSQQSAVLKCAASLESKRAPM-KISWLY-----LSSKEYVPNLLPSSKSNEAEIEITQKHYID--QYFCSVSSAAGNASVKVNFNWPTVTNIRQRPNNSIDEYFVT 1407
            ++GL+ L+ SENL   I+  +F  L+   LK  ++ N + +    +AF GL  +  L +A ++L A+P+ L  PL                         R L  L LH NP+ C C   WL    +W + Y  +N+         +C+ P  +  + L E+ + E     C +P +     ++   + + A L+C+       APM  +SWL      L+   + P +   S  ++  +  +     D   Y C VS+AAGN++     N           N S+  YF T
Sbjct:  219 LNGLEELEISENLFPVIKPGSFKGLR--SLKKLWVMNSQITVIERNAFDGLSSLVELNLAHNNLSAVPHNLFSPL-------------------------RYLVELHLHHNPWNCGCEAAWLA---RWLREYIPTNSTCCG-----RCNSPVTMRGRQLIEVEQGEGAAIQCSAPFIADAPRDLNISAGRVAELRCST------APMSSVSWLLPNGTILTHASWHPRI---SVLSDGTLNFSNVLAGDTGTYTCMVSNAAGNSNASAYLNVSAA-----ELNTSVLSYFTT 461
[Close]
BLAST of Immunoglobulin superfamily member 10 vs. Ensembl Medaka
Match: lrrc4.2 (leucine rich repeat containing 4 [Source:NCBI gene;Acc:101167534])

HSP 1 Score: 58.151 bits (139), Expect = 2.293e-8
Identity = 65/264 (24.62%), Postives = 111/264 (42.05%), Query Frame = 1 
Query:  589 GLDFLDFSENLKLYIENRAFDNLK-LKHLKLDFIGNLEFSEDAFQGL-LVASLTIAKSHLQALPYRLIEPLSRELRXXXXXXXXXXXXXXXXESLFRQLTILDLHGNPFICSCNMLWLGVTLKWRQNYYRSNTNSFSEPQFPKCDKPYYLLNQYLYEIPETEFNCRSP-KLDRI-EVQFKSQQSAVLKC-AASLESKRAPMKISWL-----YLSSKEYVPNLLPSSKSNEAEIEITQKHYIDQ--YFCSVSSAAGNASVKVNFN 1344
            GL+ L+ S+N+   ++  AF  LK L+ L +          +AF  +  +  L +A ++L +LP+ L  PL                         + L  L LH NP+ C C+++WL     W +    +N+         +C  P ++  ++L EI +T F C +P  LD   ++   + + A L+C  A++ S R      WL      L+     P +   S  N+  +  +     D   Y C VS+ AGN++     N
Sbjct:  219 GLEELEISDNVFPELKPWAFHGLKNLRKLWIMNSAITTIERNAFDDITALVELNLAHNNLSSLPHNLFTPL-------------------------QYLVELHLHHNPWSCDCDVVWLSA---WLRENIPTNSTCCG-----RCHTPIHIRGRHLVEIDQTTFQCSAPFILDAPRDLNISAARVAELRCRTAAMSSVR------WLLPNGTVLTHGSAHPRI---SVLNDGTLNFSNVLPSDTGIYTCMVSNMAGNSNASAYLN 440
[Close]
BLAST of Immunoglobulin superfamily member 10 vs. Ensembl Medaka
Match: lrrc4ba (leucine rich repeat containing 4B [Source:NCBI gene;Acc:101164310])

HSP 1 Score: 55.4546 bits (132), Expect = 1.599e-7
Identity = 59/251 (23.51%), Postives = 96/251 (38.25%), Query Frame = 1 
Query:  631 IENRAFDNLKLKHLKLDFIGNLEFSEDAFQGLLVASLTIAKSHLQALPYRLIEPLSRELRXXXXXXXXXXXXXXXXESLFRQLTILDLHGNPFICSCNMLWLGVTLKWRQNYYRSNTNSFSEPQFPKCDKPYYLLNQYLYEIPETEFNCRSPKLDR--IEVQFKSQQSAVLKCAASLESKRAPMKISWLYLSSKEYVPN-LLPSSKSNEAEIEITQKHYID----------QYFCSVSSAAGNASVKVNFN 1344
            IE  AFD+LK          NLE             L ++ + L +LP+ L  PL                          QL  + L+ NP++C+C++LWL     W +    SNT   +     +C  P  L  +Y+ E+ ++ F C +P +     ++      +A LKC  S  +      ++W+        PN  L +  S    I +     ++          QY C V++AAGN +     N
Sbjct:  251 IERNAFDDLK----------NLE------------ELNLSHNSLHSLPHDLFTPL-------------------------HQLERVHLNHNPWVCNCDVLWLS---WWLKETVPSNTTCCA-----RCHAPPILKGKYIGELDQSHFTCYAPVIVEPPTDLNVTEGMAAELKCRTSTSTT----SVNWI-------TPNGTLMTHGSYRVRISVLHDGTLNFTNVTLRDTGQYTCMVTNAAGNTTATAVLN 435
[Close]
BLAST of Immunoglobulin superfamily member 10 vs. Ensembl Medaka
Match: lrfn4b (leucine-rich repeat and fibronectin type-III domain-containing protein 4 [Source:NCBI gene;Acc:105356388])

HSP 1 Score: 54.299 bits (129), Expect = 3.228e-7
Identity = 42/155 (27.10%), Postives = 66/155 (42.58%), Query Frame = 1 
Query:  886 LDLHGNPFICSCNMLWLGVTLKWRQNYYRSNTNSFSEPQFPKCDKPYYLLNQYLYEIPETEFNCRSPKLDR--IEVQFKSQQSAVLKCAASLESKRAPMKISWLYLSSKEYVPNLLPSSKSNEA-EIEITQKHYIDQYFCSVSSAAGNASVKVNF 1341
            L+  GNP  C+C +LWL       +   R +           C  P +L  +Y + IPE EF C  P + R   ++     Q A LKC A  + +  P+ + W+    +    +   SS SN   ++ +T       Y C   +AAG A+  V+ 
Sbjct:  226 LNFGGNPLHCNCELLWL-------RRLARGD-------DMETCATPAHLAARYFWTIPEEEFTCEPPLITRHTHKLWVLEGQRATLKCRAIGDPE--PV-VHWVSPDDRIVANSSRTSSFSNGTLDMLVTVARDDGAYTCIAINAAGEATATVDL 363
[Close]
BLAST of Immunoglobulin superfamily member 10 vs. Ensembl Medaka
Match: zgc:172282 (leucine-rich repeat and fibronectin type III domain-containing protein 1-like protein [Source:NCBI gene;Acc:101174935])

HSP 1 Score: 54.299 bits (129), Expect = 3.786e-7
Identity = 97/408 (23.77%), Postives = 154/408 (37.75%), Query Frame = 1 
Query:  334 KPCPNVC-----TPCLEHAITCENGGLDGIPTELYEETTRVILVGHKFSQTFLSRQNFSKFTKPKYSIEXXXXXXXXXXXXXXXTFYDVSGLDFLDFSENLKLYIENRAFDNL-KLKHLKL--------------DFIGNLEFSEDAFQGLL------------VASLTIAKSHLQALPYRLIEPLSRELRXXXXXXXXXXXXXXXXESLFRQLTI-------------LDLHGNPFICSCNMLWLGVTLKWRQNYYRSNTNSFSEPQFPKCDKPYYLLNQYLYEIPETEFNCRSPKLDRIE--VQFKSQQSAVLKCAASLESKRAPMKISWLYL-------SSKEYV-PNLLPSSKSNEAEIEITQKHYIDQYFCSVSSAAGNASVKVNFNWPTVTNIRQRPNNSID 1392
            +PCP  C     +P L  AI C   GL  +PT +   T  + L  +    T + R++F+  T    S+  L++ ++ I  I    F D+  L  L    N    I++  F  L  L+HL L              DF+  LE  + ++  L+            V +L +  + ++ +P  +   L +  R    SN          + LF ++ +             L   GNP  C+C +LWL       +   R       E     C  P  L  +Y + IPE EF C  P L R          Q A LKC A+ + +    ++ W+          SK  V PN          EI +T +     + C  S+AAG ++ +V      V ++    + S D
Sbjct:   18 QPCPKRCMCQSLSPSL--AILCSKTGLLFVPTAIDRRTVELRLQENFI--TAVRRKDFANMT----SLLHLTLSKNTISQILPSAFSDLRRLRALHLDSNRITVIKDEHFKGLTNLRHLILANNQLHSISPHAFDDFLSTLEDLDLSYNNLIQVPWETIGHLTNVNTLNMDHNLIENVPQGVFTNLHKLARLDMTSNKLKKIPP---DPLFLRIPVYAKSKGSPLSSLVLSFGGNPLHCNCELLWL-------RRLTR-------EDDLETCASPSDLSAKYFWTIPEEEFICDPPVLTRRSPLTVIMEGQPASLKCKANGDPEP---EVHWISPEGRLISNGSKTLVFPN-------GSLEINVTSQKDSGNFTCIASNAAGESTGRVEVVVTAVPHLANSTSRSRD 390
[Close]
BLAST of Immunoglobulin superfamily member 10 vs. Planmine SMEST
Match: SMESG000021154.1 (SMESG000021154.1)

HSP 1 Score: 887.486 bits (2292), Expect = 0.000e+0
Identity = 503/504 (99.80%), Postives = 503/504 (99.80%), Query Frame = 1 
Query:  238 MAKILALLQIYFIRVSFILPLFMYDSLTAVFIKPCPNVCTPCLEHAITCENGGLDGIPTELYEETTRVILVGHKFSQTFLSRQNFSKFTKPKYSIEXXXXXXXXXXXXXXXTFYDVSGLDFLDFSENLKLYIENRAFDNLKLKHLKLDFIGNLEFSEDAFQGLLVASLTIAKSHLQALPYRLIEPLSRELRXXXXXXXXXXXXXXXXESLFRQLTILDLHGNPFICSCNMLWLGVTLKWRQNYYRSNTNSFSEPQFPKCDKPYYLLNQYLYEIPETEFNCRSPKLDRIEVQFKSQQSAVLKCAASLESKRAPMKISWLYLSSKEYVPNLLPSSKSNEAEIEITQKHYIDQYFCSVSSAAGNASVKVNFNWPTVTNIRQRPNNSIDEYFVTKPTWKTNYYQENYFFREQYTLLEXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXEQLKKSGHVTYETGFYSDSQTYDIPQYSSSDFRTKLYQPVFKILPSTRLYTDCKELNNV 1749
            MAKILALLQIYFIRVSFILPLFMYDSLTAVFIKPCPNVCTPCLEHAITCENGGLDGIPTELYEETTRVILVGHKFSQTFLSRQNFSKFTKPKYSIEQLSIRRSNIQIIRSQTFYDVSGLDFLDFSENLKLYIENRAFDNLKLKHLKLDFIGNLEFSEDAFQGLLVASLTIAKSHLQALPYRLIEPLSRELRSLFLSNNKLTSLSSKFESLFRQLTILDLHGNPFICSCNMLWLGVTLKWRQNYYRSNTNSFSEPQFPKCDKPYYLLNQYLYEIPETEFNCR PKLDRIEVQFKSQQSAVLKCAASLESKRAPMKISWLYLSSKEYVPNLLPSSKSNEAEIEITQKHYIDQYFCSVSSAAGNASVKVNFNWPTVTNIRQRPNNSIDEYFVTKPTWKTNYYQENYFFREQYTLLELLGSILGTFIITILIFILIYKFYFFKTIKMKKEQLKKSGHVTYETGFYSDSQTYDIPQYSSSDFRTKLYQPVFKILPSTRLYTDCKELNNV
Sbjct:    1 MAKILALLQIYFIRVSFILPLFMYDSLTAVFIKPCPNVCTPCLEHAITCENGGLDGIPTELYEETTRVILVGHKFSQTFLSRQNFSKFTKPKYSIEQLSIRRSNIQIIRSQTFYDVSGLDFLDFSENLKLYIENRAFDNLKLKHLKLDFIGNLEFSEDAFQGLLVASLTIAKSHLQALPYRLIEPLSRELRSLFLSNNKLTSLSSKFESLFRQLTILDLHGNPFICSCNMLWLGVTLKWRQNYYRSNTNSFSEPQFPKCDKPYYLLNQYLYEIPETEFNCRPPKLDRIEVQFKSQQSAVLKCAASLESKRAPMKISWLYLSSKEYVPNLLPSSKSNEAEIEITQKHYIDQYFCSVSSAAGNASVKVNFNWPTVTNIRQRPNNSIDEYFVTKPTWKTNYYQENYFFREQYTLLELLGSILGTFIITILIFILIYKFYFFKTIKMKKEQLKKSGHVTYETGFYSDSQTYDIPQYSSSDFRTKLYQPVFKILPSTRLYTDCKELNNV 504
[Close]
BLAST of Immunoglobulin superfamily member 10 vs. Planmine SMEST
Match: SMESG000079433.1 (SMESG000079433.1)

HSP 1 Score: 276.174 bits (705), Expect = 7.442e-85
Identity = 198/445 (44.49%), Postives = 274/445 (61.57%), Query Frame = 1 
Query:  340 CPNVCTPCLEHAITCENGGLDGIPTELYEETTRVILVGHKFSQTFLSRQNFSKFTKPKYSIEXXXXXXXXXXXXXXXTFYDVSGLDFLDFSENLKLYIENRAFDNLKLKHLKLDFIGNLEFSEDAFQGLLVASLTIAKSHLQALPYRLIEPLSRELRXXXXXXXXXXXXXXXXESLFRQLTILDLHGNPFICSCNMLWLGVTLKWRQNYYRSN--TNSFSEPQFPKCDKPYYLLNQYLYEIPETEFNCRSPKLDRIEVQFKSQQSAVLKCAASLESKRAPMKISWLYLSS----KEYVPNLLPSSKSNEAEIEITQKHYIDQYFCSVSSAAGNASVKVNFNWPTVTNIRQRPNNSIDEYFVTKPTWKTNYYQE-NYFFREQYTLLEXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXEQLKKSGHVTYETGFYSDSQTYDIPQ 1650
            CP VC  C    ++C  GGL  IPT ++E TT++ L+GH+F  + LS+ NFS F KPKYSIEQLSIR+SNI++I   TFYD+SGLD LD SEN  + I N+AF+NLKLKHLKLD I  L     AF GL V SL++  S L+ L + L+ P+S  LRSLFLSNN ++ L  KFE L  QL+ LDL GNPF C+C ++WL   L+ R         +NS     FP C  P ++ ++Y++ I E EF+C  P LD I++QF++     LKC+A L  K AP+++ W  +S     K+      P+ ++N A   I +   ++ Y C   S++GNA+++V  NWP V N R +P  +           ++N   E N+FFREQ+TLLE+LG+++GTF +T+ IF+L+        +   K   LKKSG+  YE   YSDSQTYD+PQ
Sbjct:   25 CPKVCIICFNDHLSCTTGGLLSIPTNIHESTTKITLIGHEFLSSSLSKSNFSGFFKPKYSIEQLSIRQSNIKVIEKDTFYDLSGLDNLDLSENKAIIIRNKAFNNLKLKHLKLDQIQGLVLERGAFDGLAVTSLSMKNSSLKTLSFDLMRPISNNLRSLFLSNNHISELDQKFEPLITQLSHLDLTGNPFQCTCKLVWLSRALEKRMGLGLELEFSNSGQYVNFPLCAGPAHVKDKYIHNITEAEFSCEPPSLDVIDIQFENLDIVKLKCSAKLPFKAAPIQVYWQEISDPFSLKDSQLEKNPNDETNLAVTVIRKSSSVNLYQCLAKSSSGNATIRVTINWPPVIN-RTKPLENNTPNSNNNWFGQSNKQTEKNFFFREQFTLLEMLGAVMGTFTVTLTIFLLLYRFCVKATSKVKKANSLKKSGYSIYEPAIYSDSQTYDVPQ 468
[Close]
BLAST of Immunoglobulin superfamily member 10 vs. Planmine SMEST
Match: SMESG000018621.1 (SMESG000018621.1)

HSP 1 Score: 192.971 bits (489), Expect = 6.861e-54
Identity = 166/452 (36.73%), Postives = 264/452 (58.41%), Query Frame = 1 
Query:  340 CPNVCTPCLEHAITCENGGLDGIPTELYEETTRVILVGHKFSQTFLSRQNFSKFTKPKYSIEXXXXXXXXXXXXXXXTFYDVSGLDFLDFSENLKLYIENRAFDNLKLKHLKLDFIGNLEFSEDAFQGLLVASLTIAKSHLQALPYRLIEPLSRELRXXXXXXXXXXXXXXXXESLFRQLTILDLHGNPFICSCNMLWLGVTLKWRQNYYRSNTNSFSEP--QFPKCDKPYYLLNQYLYEIPETEFNCRSPKLDRIEVQFKSQQSAVLKCAASLESKRAPMKISW---LYLSSKEYVPNLLPSSKSNEA--------EIEITQKHYIDQYFCSVSSAAGNASVKVNFNWPTVTNIRQRPNNSIDEYFVTKPTWKTNYYQENYFFREQYTLLEXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXEQLKKSGHVTYETGFYSDSQTYDIPQYS 1656
            C   C  C+E +I+C   G   +P ++ + T R IL+  +F+  FLSR+N +K + P   +E L+IR+SNI++I+  TF D++ L  LD + N  L+I++ +F  LKLK LKLD   NL+FS +AF  L V SL +++S +  LPY L++P+   L+ LF++NN L SL  +F+  F+ L  L L GN F CSC+M WL     +R    + N  +F++    FP C +P Y+  ++++EIP + FNC  P L ++++ F+S     L C+A  +  +APM ++W   +     E + ++L +SKSN           + I + +  D + C   +  GNA+  V  +WP      + PN + + Y  T  +W+ +  ++NYFF++++TLLE+ G++ GTF IT+++F +IYKF F      +K  L  +G+ TYE   YSDSQTYDIP  S
Sbjct:   25 CGKFCDACVEDSISCTKPGFKEMPQQMSKTTKRFILISQQFTNNFLSRENLTKISPPNVFLEYLTIRKSNIKLIKPMTFSDLTVLRALDLTYNNNLFIDSGSFSGLKLKLLKLDNNDNLKFSINAFVDLTVESLHMSQSSIFDLPYDLLKPILPFLKKLFINNNNLISLDPRFQIPFKNLQTLYLQGNSFDCSCSMKWLTAVYVYRTTNGKYNKGTFTDEIQSFPTCKEPKYMEGKHMHEIPLSLFNCDPPNLTQLKIDFQSATETELSCSAVQKVDQAPMTVNWFTDIINGIGEKMFSIL-NSKSNPTTDRNVHVETVLIQKNNSTDSFQCIAKNLNGNATAIVRISWPPS---EKFPNPNRNVYQSTIDSWQKS-EEDNYFFQKRFTLLEMFGAVFGTFAITLILFFMIYKFVFINRSTDRKAILPPNGYTTYEAAVYSDSQTYDIPGNS 471
[Close]
BLAST of Immunoglobulin superfamily member 10 vs. Planmine SMEST
Match: SMESG000001555.1 (SMESG000001555.1)

HSP 1 Score: 187.193 bits (474), Expect = 3.023e-51
Identity = 144/417 (34.53%), Postives = 206/417 (49.40%), Query Frame = 1 
Query:  340 CPNVCTPCLEHAITCENGGLDGIPTELYEETTRVILVGHKFSQTFLSRQNFSKFTKPKYSIEXXXXXXXXXXXXXXXTFYDVSGLDFLDFSENLKLYIENRAFDNLKLKHLKLDFIGNLEFSEDAFQGLLVASLTIAKSHLQALPYRLIEPLSRELRXXXXXXXXXXXXXXXXESLFRQLTILDLHGNPFICSCNMLWLGVTLKWRQNYYRSNTNSFSEPQ---------FPKCDKPYYLLNQYLYEIPETEFNCRSPKLDRIEVQFKSQQSAVLKCAASLESK--RAPMKISW-------------LYLSSKEYVPNLLPSSKSNEAEIEITQKHYID--------QYFCSVSSAAGNASVKVNFNWPTVTNI--RQRPNNSIDEYFVTKPT----WKTNYYQENYFFREQYTLLE 1476
            CP  C+ CL   I+C  G L  IP +L  +T  + L G       LS  NF+    PKY I  LSIR  +I  + S TF  +  L  LD SEN +L I + +F  L LK LKLD IG L  S D+F  L   SL++  S LQ+L + + +P+S  L+ L + NN++  L   FE LF +L  ++L  N FIC C++LWL   L+ + ++Y+S  N FS+ +         FPKC  P YL ++ L  I E+EFNC+ P++ +IE+   S    ++ C+   E K  + P K+ W             +Y  S+  V     S   N    E + K   D         + C   + AG + V V  +WP   N     +PN+   E    +PT    W T   Q++YFF +QYTLLE
Sbjct:   28 CPMHCSICLPSHISCTTGSLTSIPNQLQPKTETITLSGQLQFHPVLSSANFTDLAYPKYQIHTLSIRSCSIYELSSHTFSQLVMLKILDLSENQRLTIMSSSFSGLHLKVLKLDDIGKLMLSPDSFSDLSTESLSMKASRLQSLNFNIFQPISHSLKHLNIENNQIKILDQSFEPLFYRLESVNLKDNTFICYCDLLWLSKALRSKLSFYKSQ-NRFSDGKADSNSDVNNFPKCVGPTYLRDRQLQTISESEFNCQVPQIAQIEIDLLSVFGGMMSCSIKPEEKGHKIPTKVFWEKQHPQNGKVFQRVYEKSQNAVDGF--SLLENNGIAEFSSKIKFDSDRNKNQENFNCVAENKAGRSLVSVQISWPKFNNSLDSSQPNSPTTESEKKQPTDHYQWNTP-NQKSYFFTKQYTLLE 440
[Close]
BLAST of Immunoglobulin superfamily member 10 vs. Planmine SMEST
Match: SMESG000026559.1 (SMESG000026559.1)

HSP 1 Score: 174.096 bits (440), Expect = 4.910e-47
Identity = 144/473 (30.44%), Postives = 246/473 (52.01%), Query Frame = 1 
Query:  274 IRVSFILPLFMYD---SLTAVFIKPCPNVC--TPCLEHAITCENGGLDGIPTELYEETTRVILVGHKFSQTFLSRQNFSKFTKPKYSIEXXXXXXXXXXXXXXXTFYDVSGLDFLDFSENLKLYIENRAFDNLKLKHLKLDFIGNLEFSEDAFQGLLVASLTIAKSHLQALPYRLIEPLSRELRXXXXXXXXXXXXXXXXESLFRQLTILDLHGNPFICSCNMLWLGVTLKWRQNYYRSNTNSFSEPQFPKCDKPYYLLNQYLYEIPETEFNCRSPKLDRIEVQFKSQQSAVLKCAASLESKRAPMKISWLYLSSKEYVPNLLPSSKSNEAEIEITQKHYIDQYFCSVSSAAGNASVKVNFNWPT--VTNIRQRPNN---SIDEYFVTKPTWKTNYYQENYFFREQYTLLEXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXEQLKKSGHVTYETGFYSDSQTYDIPQYSSS 1662
            +++ F+LP+ ++    + T+    PCP+VC    C    + C +GGL  IP  L+++T ++I+   +FS   L+  NFS +  P Y IE+++++   +  I S  F  ++ L  LD S NL   I    F  L L+ L+LD    ++F   +F+GL VA L++   +L  L + +   +S  L+ L L+NNKL  +  +F  LF  L  L ++ NPF C+CN+ WL   L  R+      ++S   P   +C+ P  +  + + ++   +F+C SP+L  I+V   S  SA L C +  ++  +P  + W+      YVP +     S  A + + +K  ID+Y C + +     +V ++ +WP   V N  Q  N    S ++     P   +  +  + F+ +Q+TLLE++G I+GTF IT+++F+ IY+       +      KK  +++YET   SDSQTYDIP  ++ 
Sbjct:    1 MKIPFLLPMLLFILFLAKTSAHSNPCPSVCHEMACQTGVLACTDGGLLQIPPVLHQKTHKIIVSNQRFSSPHLTYSNFSNYGPPNYKIEKIALQFCELVSIASNCFSHLTDLRVLDLSHNLLGEIPPDTFKALHLQFLRLDDNKMIQFHRFSFRGLNVAELSLFDCNLTELDFEVFSEISERLKKLILTNNKLNVIDKRFRILFENLPDLQINENPFNCTCNLRWLNSVLVSRKKAINL-SSSKRIPNQAQCNYPDRVKGKQIADLDLKDFDCDSPRLKLIDVFMTSTSSAKLTCISEPKAHSSP-DVIWMAEHRNTYVPEI---QSSENASLSVLRKSRIDKYKCVIKNNNDYVTVVISIHWPVKRVNNASQSLNTLGVSPNDMIPYLPNANSTLHVRSVFYEKQFTLLEMIGGIVGTFTITMILFLCIYRHLAMTMKRND----KKKWYLSYETAIGSDSQTYDIPNNTAG 464
The following BLAST results are available for this feature:
BLAST of Immunoglobulin superfamily member 10 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
LRRC46.435e-1025.56leucine rich repeat containing 4 [Source:HGNC Symb... [more]
LGI43.454e-728.57leucine rich repeat LGI family member 4 [Source:HG... [more]
LGI45.165e-728.65leucine rich repeat LGI family member 4 [Source:HG... [more]
LGI45.752e-727.89leucine rich repeat LGI family member 4 [Source:HG... [more]
LRRC4B2.593e-622.93leucine rich repeat containing 4B [Source:HGNC Sym... [more]
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BLAST of Immunoglobulin superfamily member 10 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Immunoglobulin superfamily member 10 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 3
Match NameE-valueIdentityDescription
sli6.355e-1125.81gene:FBgn0264089 transcript:FBtr0330730[more]
sli6.587e-1125.81gene:FBgn0264089 transcript:FBtr0330729[more]
sli6.587e-1125.81gene:FBgn0264089 transcript:FBtr0330732[more]
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BLAST of Immunoglobulin superfamily member 10 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
lrrc4.21.428e-1025.93leucine rich repeat containing 4.2 [Source:ZFIN;Ac... [more]
lrrc4.15.431e-825.27leucine rich repeat containing 4.1 [Source:ZFIN;Ac... [more]
lrrc4.16.399e-825.27leucine rich repeat containing 4.1 [Source:ZFIN;Ac... [more]
lrrc4.17.591e-825.27leucine rich repeat containing 4.1 [Source:ZFIN;Ac... [more]
lrrc4.17.838e-825.27leucine rich repeat containing 4.1 [Source:ZFIN;Ac... [more]
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BLAST of Immunoglobulin superfamily member 10 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 2
Match NameE-valueIdentityDescription
ENSXETT00000007893.13.515e-927.78leucine rich repeat and fibronectin type III domai... [more]
lrrc41.645e-723.68leucine rich repeat containing 4 [Source:NCBI gene... [more]
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BLAST of Immunoglobulin superfamily member 10 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Lrrc44.293e-1125.94leucine rich repeat containing 4 [Source:MGI Symbo... [more]
Lrfn51.565e-623.62leucine rich repeat and fibronectin type III domai... [more]
Lrfn51.848e-628.03leucine rich repeat and fibronectin type III domai... [more]
Lrrc4b1.886e-622.93leucine rich repeat containing 4B [Source:MGI Symb... [more]
Lrrc4c1.986e-624.72leucine rich repeat containing 4C [Source:MGI Symb... [more]
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BLAST of Immunoglobulin superfamily member 10 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 4
Match NameE-valueIdentityDescription
sp|Q99PH1|LRRC4_MOUSE3.003e-1025.94Leucine-rich repeat-containing protein 4 OS=Mus mu... [more]
sp|Q45R42|LRRC4_RAT3.389e-1025.94Leucine-rich repeat-containing protein 4 OS=Rattus... [more]
sp|Q9HBW1|LRRC4_HUMAN3.090e-925.56Leucine-rich repeat-containing protein 4 OS=Homo s... [more]
sp|Q8N135|LGI4_HUMAN2.480e-628.65Leucine-rich repeat LGI family member 4 OS=Homo sa... [more]
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BLAST of Immunoglobulin superfamily member 10 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A5P8I4L04.606e-4330.23PXDN-like protein OS=Schmidtea mediterranea OX=793... [more]
I1ZIL59.720e-3131.75Slit-2 OS=Schmidtea mediterranea OX=79327 PE=2 SV=... [more]
R7V5M31.911e-2930.14Ig-like domain-containing protein OS=Capitella tel... [more]
A0A068YC119.548e-2727.31Variable lymphocyte receptor OS=Echinococcus multi... [more]
A0A2H1CUL74.659e-2627.82Leucine Rich repeat-containing domain protein OS=F... [more]
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BLAST of Immunoglobulin superfamily member 10 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
lrrc4.21.471e-1026.12leucine rich repeat containing 4.2 [Source:ZFIN;Ac... [more]
lrrc4ba4.036e-725.50leucine-rich repeat-containing protein 4B-like [So... [more]
lrrc4ba4.036e-725.50leucine-rich repeat-containing protein 4B-like [So... [more]
lrrc4ba4.227e-725.42leucine-rich repeat-containing protein 4B-like [So... [more]
lrrc4ca7.811e-723.53leucine-rich repeat-containing protein 4C [Source:... [more]
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BLAST of Immunoglobulin superfamily member 10 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 1
Match NameE-valueIdentityDescription
lrfn5a8.624e-923.66leucine rich repeat and fibronectin type III domai... [more]
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BLAST of Immunoglobulin superfamily member 10 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Immunoglobulin superfamily member 10 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Immunoglobulin superfamily member 10 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
lrrc4.11.800e-1025.00leucine-rich repeat-containing protein 4 [Source:N... [more]
lrrc4.22.293e-824.62leucine rich repeat containing 4 [Source:NCBI gene... [more]
lrrc4ba1.599e-723.51leucine rich repeat containing 4B [Source:NCBI gen... [more]
lrfn4b3.228e-727.10leucine-rich repeat and fibronectin type-III domai... [more]
zgc:1722823.786e-723.77leucine-rich repeat and fibronectin type III domai... [more]
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BLAST of Immunoglobulin superfamily member 10 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000021154.10.000e+099.80SMESG000021154.1[more]
SMESG000079433.17.442e-8544.49SMESG000079433.1[more]
SMESG000018621.16.861e-5436.73SMESG000018621.1[more]
SMESG000001555.13.023e-5134.53SMESG000001555.1[more]
SMESG000026559.14.910e-4730.44SMESG000026559.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30027888 ID=SMED30027888|Name=Immunoglobulin superfamily member 10|organism=Schmidtea mediterranea sexual|type=transcript|length=2009bp
ACAATTGATTATTTTTATCTTTATAAATCATTTATAAACTGCTTTACATT
TTGGTGTTTAGCAAATTGATTTTATTTTCAATGATTTAATGATTTATGCA
GCTTATTTCAACCAATACCAGATATCTACATAAATTTACCATTTATTTCG
AAATTGGATGGATATTCTGACAATCTAGTCTGAAAATTCTGCAATTATTA
AACCAAATGTTAAATTAAAAATTTTCTTTGTGATAAAATGGCTAAGATAT
TGGCTTTGTTACAAATCTATTTTATAAGAGTCAGTTTTATCTTGCCACTG
TTTATGTATGATTCATTAACAGCTGTGTTCATCAAACCTTGTCCAAATGT
CTGTACGCCGTGCTTGGAACACGCAATAACATGCGAAAATGGCGGACTAG
ATGGAATACCAACTGAACTCTATGAAGAAACGACAAGAGTCATTTTGGTT
GGACACAAATTCTCACAGACTTTTCTCAGTCGACAAAACTTTTCCAAATT
CACAAAGCCAAAGTATTCAATTGAACAATTATCGATTCGTCGAAGTAATA
TTCAAATTATTCGCTCTCAAACCTTCTACGACGTGAGTGGATTGGATTTT
CTAGATTTTTCGGAGAATCTGAAATTATATATTGAAAATCGAGCTTTCGA
CAACTTGAAATTGAAACATCTCAAACTCGATTTCATCGGCAATTTGGAAT
TCAGTGAAGACGCATTTCAAGGATTGTTAGTAGCATCGCTTACAATTGCA
AAAAGTCACCTCCAAGCACTTCCTTATAGATTAATTGAGCCGTTATCTCG
TGAATTGCGATCTCTGTTTTTATCGAATAATAAATTGACGAGTTTGAGCT
CGAAATTCGAATCCCTATTTCGGCAGTTAACCATTCTTGATCTCCACGGA
AATCCGTTCATTTGCTCATGCAACATGTTATGGTTGGGAGTCACTTTGAA
ATGGCGTCAGAACTATTATCGTTCCAATACTAATTCGTTTTCTGAGCCCC
AGTTTCCGAAATGTGACAAACCTTATTATTTATTGAATCAATATCTCTAC
GAGATCCCCGAAACTGAATTCAATTGTCGTTCACCAAAATTAGATCGAAT
CGAAGTTCAATTCAAATCCCAACAATCAGCTGTATTGAAATGTGCAGCGT
CACTTGAATCCAAACGAGCTCCGATGAAAATCTCGTGGCTATATCTCAGT
TCGAAAGAGTACGTTCCAAATTTATTGCCCAGCTCGAAAAGCAACGAAGC
AGAAATCGAAATAACCCAGAAACATTACATCGACCAGTATTTCTGTTCTG
TGAGCAGTGCGGCCGGAAATGCCAGTGTAAAGGTGAATTTTAATTGGCCG
ACTGTCACCAATATCCGGCAACGGCCGAATAATTCTATCGACGAATACTT
TGTCACTAAACCGACTTGGAAGACGAATTATTATCAGGAAAATTATTTTT
TCCGAGAACAATATACTCTGTTGGAGTTACTTGGATCTATCCTTGGGACA
TTTATTATTACAATATTGATATTTATTTTAATTTACAAATTTTATTTCTT
CAAAACAATTAAAATGAAAAAGGAACAATTAAAAAAGTCTGGTCATGTTA
CATATGAAACCGGATTTTATTCCGATTCCCAAACCTATGACATTCCACAG
TACTCCTCCTCAGATTTCAGAACGAAACTTTATCAGCCAGTGTTTAAAAT
TTTGCCGTCGACTCGACTTTATACAGATTGTAAAGAACTGAATAATGTTT
GACGTATGAGTTTATTTTAAGCTGTGAATCCTGTTGCATTTGAAGAAAAA
AATCACATTTTTATTTTATCTGATTAAGATGTATATTATCAAAAAATTCA
TATCCTTTTGAGGATTATTTAGTGGCAAATAGAAGTGCACTAAGATTTTT
CATTTTCCAACGCCAAATCCCGTTTGCAGACTTCATAAAAATCGGATGAG
CGCGCAAATTTATGGTTAATGACAAAATTTCCTAATATCTACAAATAAGA
TTACTACCC
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protein sequence of SMED30027888-orf-1

>SMED30027888-orf-1 ID=SMED30027888-orf-1|Name=SMED30027888-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=505bp
MAKILALLQIYFIRVSFILPLFMYDSLTAVFIKPCPNVCTPCLEHAITCE
NGGLDGIPTELYEETTRVILVGHKFSQTFLSRQNFSKFTKPKYSIEQLSI
RRSNIQIIRSQTFYDVSGLDFLDFSENLKLYIENRAFDNLKLKHLKLDFI
GNLEFSEDAFQGLLVASLTIAKSHLQALPYRLIEPLSRELRSLFLSNNKL
TSLSSKFESLFRQLTILDLHGNPFICSCNMLWLGVTLKWRQNYYRSNTNS
FSEPQFPKCDKPYYLLNQYLYEIPETEFNCRSPKLDRIEVQFKSQQSAVL
KCAASLESKRAPMKISWLYLSSKEYVPNLLPSSKSNEAEIEITQKHYIDQ
YFCSVSSAAGNASVKVNFNWPTVTNIRQRPNNSIDEYFVTKPTWKTNYYQ
ENYFFREQYTLLELLGSILGTFIITILIFILIYKFYFFKTIKMKKEQLKK
SGHVTYETGFYSDSQTYDIPQYSSSDFRTKLYQPVFKILPSTRLYTDCKE
LNNV*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000030midline
PLANA:0000034epidermis
PLANA:0000099neuron
PLANA:0000103central nervous system
PLANA:0000418head
Vocabulary: INTERPRO
TermDefinition
IPR025875Leu-rich_rpt_4
IPR013783Ig-like_fold
IPR001611Leu-rich_rpt
IPR032675LRR_dom_sf
IPR007110Ig-like_dom
Vocabulary: molecular function
TermDefinition
GO:0005515protein binding
Vocabulary: cellular component
TermDefinition
GO:0016020membrane
GO:0016021integral component of membrane
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR032675Leucine-rich repeat domain superfamilyGENE3DG3DSA:3.80.10.10coord: 152..282
e-value: 1.1E-19
score: 72.4
IPR032675Leucine-rich repeat domain superfamilyGENE3DG3DSA:3.80.10.10coord: 31..151
e-value: 1.8E-9
score: 38.9
IPR025875Leucine rich repeat 4PFAMPF12799LRR_4coord: 189..225
e-value: 2.8E-6
score: 27.6
IPR001611Leucine-rich repeatPFAMPF13855LRR_8coord: 96..148
e-value: 4.8E-7
score: 29.4
IPR001611Leucine-rich repeatPROSITEPS51450LRRcoord: 213..234
score: 4.978
IPR001611Leucine-rich repeatPROSITEPS51450LRRcoord: 189..210
score: 7.774
NoneNo IPR availablePANTHERPTHR45842FAMILY NOT NAMEDcoord: 33..367
NoneNo IPR availableSUPERFAMILYSSF52058L domain-likecoord: 47..283
NoneNo IPR availableTMHMMTMhelixcoord: 415..437
IPR007110Immunoglobulin-like domainPROSITEPS50835IG_LIKEcoord: 283..369
score: 7.831