Dynein light chain

Overview
NameDynein light chain
Smed IDSMED30027878
Length (bp)967
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Dynein light chain (SMED30027878) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Dynein light chain (SMED30027878) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30027878

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 3

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
protonephridiaSMED30027878h1SMcG0015828 dd_Smed_v4_15092_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
epidermisSMED30027878h1SMcG0015828 dd_Smed_v4_15092_0_1dd_Smed_v4PMID:28292427
Wurtzel et al., 2017		whole organism asexual adult single-cell RNA-sequencing evidence
dorsal region of the whole animalSMED30027878h1SMcG0015828 dd_Smed_v4_15092_0_1dd_Smed_v4PMID:28292427
Wurtzel et al., 2017		whole organism asexual adult colorimetric in situ hybridization evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Dynein light chain vs. Ensembl Celegans
Match: dlc-2 (Probable dynein light chain 2, cytoplasmic [Source:UniProtKB/Swiss-Prot;Acc:Q21557])

HSP 1 Score: 47.3654 bits (111), Expect = 5.821e-7
Identity = 26/82 (31.71%), Postives = 47/82 (57.32%), Query Frame = 1 
Query:  646 IDEDPLNDPKFKDFCMKICQEATNNENDFISIAKYLKSVLDVKFGRSWNVVVDIDAYGSFLSHEPGAFIHIKVRKFAILLWK 891
            + E  + DP+ +D  + + +EA    N    +A ++K  LD KFG +W+V+     +GS +S+E G FI +K  K  ++++K
Sbjct:    8 VKETDMEDPQ-RDMVISVVREAQRLYNIDKDVAAFVKEELDKKFGATWHVICG-KCFGSRVSYEMGHFILLKCNKVNVMIYK 87
[Close]
BLAST of Dynein light chain vs. UniProt/SwissProt
Match: sp|P14202|TEGU_SCHMA (Tegument antigen OS=Schistosoma mansoni OX=6183 GN=A12 PE=2 SV=1)

HSP 1 Score: 77.7962 bits (190), Expect = 7.487e-16
Identity = 58/184 (31.52%), Postives = 90/184 (48.91%), Query Frame = 1 
Query:  358 EFIKAFEEIDSDNSGEITRGELIRYMRLKNYKPAFVEKWLNIFDADNSGTITLEEFCNTLGLIPNKNYQXXXXXXXXXXXXXXXXXXXXPLYDLYVIDEDPLNDPKFKDFCMKICQEATNNE---NDFISIAKYLKSVLDVKFGRSWNVVVDIDAYGSFLSHEPGAFIHIKVRKFAILLWKVPA 900
            EFI+AF EID+D++  I + ELI+Y +        ++ W+  FD D    I++EEFC   GL   K  + R EK + +KE   +   L P  ++       ++  K  + C +  +   N     ND   +A  +KS+LD  +GR W VV+   +Y    SHEP   I  K   +  L W+ P+
Sbjct:   12 EFIRAFLEIDADSNEMIDKQELIKYCQKYRLDMKLIDPWIARFDTDKDNKISIEEFCRGFGL---KVSEIRREKDELKKERDGKFPKLPPNIEIIAA---TMSKTKQYEICCQFKEYVDNTSRTGNDMREVANKMKSLLDNTYGRVWQVVLLTGSYWMNFSHEPFLSIQFKYNNYVCLAWRTPS 189
[Close]
BLAST of Dynein light chain vs. UniProt/SwissProt
Match: sp|Q21557|DYL2_CAEEL (Probable dynein light chain 2, cytoplasmic OS=Caenorhabditis elegans OX=6239 GN=dlc-2 PE=3 SV=2)

HSP 1 Score: 47.3654 bits (111), Expect = 7.404e-6
Identity = 26/82 (31.71%), Postives = 47/82 (57.32%), Query Frame = 1 
Query:  646 IDEDPLNDPKFKDFCMKICQEATNNENDFISIAKYLKSVLDVKFGRSWNVVVDIDAYGSFLSHEPGAFIHIKVRKFAILLWK 891
            + E  + DP+ +D  + + +EA    N    +A ++K  LD KFG +W+V+     +GS +S+E G FI +K  K  ++++K
Sbjct:    8 VKETDMEDPQ-RDMVISVVREAQRLYNIDKDVAAFVKEELDKKFGATWHVICG-KCFGSRVSYEMGHFILLKCNKVNVMIYK 87
[Close]
BLAST of Dynein light chain vs. TrEMBL
Match: A0A267EIW9 (Dynein light chain OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig005207g1 PE=3 SV=1)

HSP 1 Score: 147.902 bits (372), Expect = 6.318e-40
Identity = 81/184 (44.02%), Postives = 116/184 (63.04%), Query Frame = 1 
Query:  355 MEFIKAFEEIDSDNSGEITRGELIRYMRLKNYKPAFVEKWLNIFDADNSGTITLEEFCNTLGLIPNKNYQXXXXXXXXXXXXXXXXXXXXPLYDLYVIDEDPLNDPKFKDFCMKICQEATN---NENDFISIAKYLKSVLDVKFGRSWNVVVDIDAYGSFLSHEPGAFIHIKVRKFAILLWKVP 897
            M+F+ AFE+IDSD SGEIT  EL  Y R  NY+  FVEKWL +FD DNSGTIT+EEFC+TLGL+P + Y ++++  + + E          +  + +I EDP      K+  ++I ++A     NE D   IA+++K+ LD  FGR+W+V+V    YGSF +HE G+  H  V + A+L+WK P
Sbjct:    1 MDFLHAFEDIDSDFSGEITTEELEAYCRRHNYEDRFVEKWLRLFDHDNSGTITIEEFCDTLGLVPKQEYMEKVQTNREKSEGGGI------MDGVKIITEDPELSDSTKEEIVRIARQAQEQFVNERD---IARHMKARLDDMFGRAWHVIVGRYQYGSFCTHETGSLFHFYVLRNAVLVWKTP 175
[Close]
BLAST of Dynein light chain vs. TrEMBL
Match: A0A1I8I7N8 (Dynein light chain OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig001380g1 PE=3 SV=1)

HSP 1 Score: 145.591 bits (366), Expect = 4.139e-39
Identity = 81/184 (44.02%), Postives = 113/184 (61.41%), Query Frame = 1 
Query:  355 MEFIKAFEEIDSDNSGEITRGELIRYMRLKNYKPAFVEKWLNIFDADNSGTITLEEFCNTLGLIPNKNYQXXXXXXXXXXXXXXXXXXXXPLYDLYVIDEDPLNDPKFKDFCMKI---CQEATNNENDFISIAKYLKSVLDVKFGRSWNVVVDIDAYGSFLSHEPGAFIHIKVRKFAILLWKVP 897
            M+F+ A+E ID+D SGEIT  EL  Y R  NY+  FVEKWL +FD DNSGTIT+EEFC TLGL+P + Y ++++  + +   +        +  + +I EDP    + K+  +++    QE   NE D   IA+Y+KS LD KF R+W+V+V    YGSF +HE G   H  V + AIL+WK P
Sbjct:    1 MDFLTAYEAIDTDFSGEITSEELEAYCRKHNYEDKFVEKWLRLFDHDNSGTITIEEFCETLGLVPKQEYMEKVQINREKSSGV--------MDGVKIITEDPDMTDELKEEIVQLARTAQEQFENERD---IARYMKSELDAKFDRAWHVIVGRFQYGSFCTHEVGRLFHFYVVRNAILVWKTP 173
[Close]
BLAST of Dynein light chain vs. TrEMBL
Match: A0A1I8IZR3 (Uncharacterized protein OS=Macrostomum lignano OX=282301 PE=4 SV=1)

HSP 1 Score: 149.058 bits (375), Expect = 1.818e-37
Identity = 82/185 (44.32%), Postives = 117/185 (63.24%), Query Frame = 1 
Query:  352 SMEFIKAFEEIDSDNSGEITRGELIRYMRLKNYKPAFVEKWLNIFDADNSGTITLEEFCNTLGLIPNKNYQXXXXXXXXXXXXXXXXXXXXPLYDLYVIDEDPLNDPKFKDFCMKICQEATN---NENDFISIAKYLKSVLDVKFGRSWNVVVDIDAYGSFLSHEPGAFIHIKVRKFAILLWKVP 897
            SM+F+ AFE+IDSD SGEIT  EL  Y R  NY+  FVEKWL +FD DNSGTIT+EEFC+TLGL+P + Y ++++  + + E          +  + +I EDP      K+  ++I ++A     NE D   IA+++K+ LD  FGR+W+V+V    YGSF +HE G+  H  V + A+L+WK P
Sbjct:  282 SMDFLHAFEDIDSDFSGEITTEELEAYCRRHNYEDRFVEKWLRLFDHDNSGTITIEEFCDTLGLVPKQEYMEKVQTNREKSEGGGI------MDGVKIITEDPELSDSTKEEIVRIARQAQEQFVNERD---IARHMKARLDDMFGRAWHVIVGRYQYGSFCTHETGSLFHFYVLRNAVLVWKTP 457
[Close]
BLAST of Dynein light chain vs. TrEMBL
Match: A0A1I8IZM2 (Uncharacterized protein OS=Macrostomum lignano OX=282301 PE=4 SV=1)

HSP 1 Score: 138.272 bits (347), Expect = 1.703e-35
Identity = 78/179 (43.58%), Postives = 112/179 (62.57%), Query Frame = 1 
Query:  355 MEFIKAFEEIDSDNSGEITRGELIRYMRLKNYKPAFVEKWLNIFDADNSGTITLEEFCNTLGLIPNKNYQXXXXXXXXXXXXXXXXXXXXPLYDLYVIDEDPLNDPKFKDFCMKICQEATN---NENDFISIAKYLKSVLDVKFGRSWNVVVDIDAYGSFLSHEPGAFIHIKVRKFAIL 882
            M+F+ AFE+IDSD SGEIT  EL  Y R  NY+  FVEKWL +FD DNSGTIT+EEFC+TLGL+P + Y ++++  + + E          +  + +I EDP      K+  ++I ++A     NE D   IA+++K+ LD  FGR+W+V+V    YGSF +HE G+  H  V + A+L
Sbjct:    1 MDFLHAFEDIDSDFSGEITTEELEAYCRRHNYEDRFVEKWLRLFDHDNSGTITIEEFCDTLGLVPKQEYMEKVQTNREKSEGGGI------MDGVKIITEDPELSDSTKEEIVRIARQAQEQFVNERD---IARHMKARLDDMFGRAWHVIVGRYQYGSFCTHETGSLFHFYVLRNAVL 170
[Close]
BLAST of Dynein light chain vs. TrEMBL
Match: A0A1I8ITI7 (Uncharacterized protein OS=Macrostomum lignano OX=282301 PE=4 SV=1)

HSP 1 Score: 141.739 bits (356), Expect = 1.151e-33
Identity = 79/181 (43.65%), Postives = 111/181 (61.33%), Query Frame = 1 
Query:  352 SMEFIKAFEEIDSDNSGEITRGELIRYMRLKNYKPAFVEKWLNIFDADNSGTITLEEFCNTLGLIPNKNYQXXXXXXXXXXXXXXXXXXXXPLYDLYVIDEDPLNDPKFKDFCMKI---CQEATNNENDFISIAKYLKSVLDVKFGRSWNVVVDIDAYGSFLSHEPGAFIHIKVRKFAILL 885
            +M+F+ A+E ID+D SGEIT  EL  Y R  NY+  FVEKWL +FD DNSGTIT+EEFC TLGL+P + Y ++++  + +   +        +  + +I EDP    + K+  +++    QE   NE D   IA+Y+KS LD KF R+W+V+V    YGSF +HE G   H  V + AILL
Sbjct:  813 TMDFLTAYEAIDTDFSGEITSEELEAYCRKHNYEDKFVEKWLRLFDHDNSGTITIEEFCETLGLVPKQEYMEKVQINREKSSGV--------MDGVKIITEDPDITDELKEEIVQLARTAQEQFENERD---IARYMKSELDAKFDRAWHVIVGRFQYGSFCTHEVGRLFHFYVVRNAILL 982
[Close]
BLAST of Dynein light chain vs. Ensembl Yeast
Match: DYN2 (Cytoplasmic light chain dynein, microtubule motor protein; required for intracellular transport and cell division; involved in mitotic spindle positioning; forms complex with dynein intermediate chain Pac11p that promotes Dyn1p homodimerization, potentiates motor processivity; Dyn2p-Pac11p complex important for interaction of dynein motor complex with dynactin complex; acts as molecular glue to dimerize, stabilize Nup82-Nsp1-Nup159 complex module of cytoplasmic pore filaments [Source:SGD;Acc:S000002832])

HSP 1 Score: 46.2098 bits (108), Expect = 2.419e-7
Identity = 24/75 (32.00%), Postives = 44/75 (58.67%), Query Frame = 1 
Query:  673 KFKDFCMKICQEATNNENDFISIAKYLKSVLDVKFGRSWNVVVDIDAYGSFLSHEPGAFIHIKVRKFAILLWKVP 897
            K K+  + I ++A +       IA  +K  LDVK+G +W+V+V  + +GS+++HE G F++  +   A L++K  
Sbjct:   19 KLKEDILTISKDALDKYQLERDIAGTVKKQLDVKYGNTWHVIVGKN-FGSYVTHEKGHFVYFYIGPLAFLVFKTA 92
[Close]
BLAST of Dynein light chain vs. Planmine SMEST
Match: SMESG000042102.1 (SMESG000042102.1)

HSP 1 Score: 329.717 bits (844), Expect = 1.062e-114
Identity = 182/182 (100.00%), Postives = 182/182 (100.00%), Query Frame = 1 
Query:  355 MEFIKAFEEIDSDNSGEITRGELIRYMRLKNYKPAFVEKWLNIFDADNSGTITLEEFCNTLGLIPNKNYQXXXXXXXXXXXXXXXXXXXXPLYDLYVIDEDPLNDPKFKDFCMKICQEATNNENDFISIAKYLKSVLDVKFGRSWNVVVDIDAYGSFLSHEPGAFIHIKVRKFAILLWKVPA 900
            MEFIKAFEEIDSDNSGEITRGELIRYMRLKNYKPAFVEKWLNIFDADNSGTITLEEFCNTLGLIPNKNYQKRIEKRKSEKELLKRKSLLIPLYDLYVIDEDPLNDPKFKDFCMKICQEATNNENDFISIAKYLKSVLDVKFGRSWNVVVDIDAYGSFLSHEPGAFIHIKVRKFAILLWKVPA
Sbjct:    1 MEFIKAFEEIDSDNSGEITRGELIRYMRLKNYKPAFVEKWLNIFDADNSGTITLEEFCNTLGLIPNKNYQKRIEKRKSEKELLKRKSLLIPLYDLYVIDEDPLNDPKFKDFCMKICQEATNNENDFISIAKYLKSVLDVKFGRSWNVVVDIDAYGSFLSHEPGAFIHIKVRKFAILLWKVPA 182
[Close]
BLAST of Dynein light chain vs. Planmine SMEST
Match: SMESG000008592.1 (SMESG000008592.1)

HSP 1 Score: 149.058 bits (375), Expect = 9.172e-44
Identity = 76/188 (40.43%), Postives = 120/188 (63.83%), Query Frame = 1 
Query:  355 MEFIKAFEEIDSDNSGEITRGELIRYMRLKNYKPAFVEKWLNIFDADNSGTITLEEFCNTLGLIPNKNYQXXXXXXXXXXXXXXX------XXXXXPLYDLYVIDEDPLNDPKFKDFCMKICQEATNNENDFISIAKYLKSVLDVKFGRSWNVVVDIDAYGSFLSHEPGAFIHIKVRKFAILLWKVPA 900
            M+ IKAFEEID+D SGEIT+ ELI YM  K+Y+  FV KW+ IFD +N+G ITLEEFC+ LGL PN++Y ++++ ++ E + + +      +     + D+ +I EDP    +F+ F + +  +A+ +      IAK +K  LD ++ + W+VVV    +GSF+SH+ G F+H K+  F  L+W+ P+
Sbjct:    1 MDLIKAFEEIDTDYSGEITKDELINYMIKKDYEMGFVNKWMEIFDPNNTGRITLEEFCDALGLQPNEDYLQQVQTKQEESKPMIQICPPFNEETNEEIIDVEIIREDPDTTAEFRQFAIDVSHQASKDHKLEKDIAKSIKKKLDEEYNKIWHVVVARSTFGSFISHKSGKFMHYKIENFCYLIWQTPS 188
[Close]
BLAST of Dynein light chain vs. Planmine SMEST
Match: SMESG000078154.1 (SMESG000078154.1)

HSP 1 Score: 123.635 bits (309), Expect = 6.647e-32
Identity = 64/187 (34.22%), Postives = 107/187 (57.22%), Query Frame = 1 
Query:  337 TTHCFSMEFIKAFEEIDSDNSGEITRGELIRYMRLKNYKPAFVEKWLNIFDADNSGTITLEEFCNTLGLIPNKNYQXXXXXXXXXXXXXXXXXXXXPLYDLYVIDEDPLNDPKFKDFCMKICQEATNNENDFISIAKYLKSVLDVKFGRSWNVVVDIDAYGSFLSHEPGAFIHIKVRKFAILLWKVP 897
            +    S++F+K FEEID D SGEI+  E+  YMR  N++  FV+KWL +F+ +  G IT+E +C +LGLIP ++Y  R+   +    L+ R +      ++ +I  +PL D   K F +++ ++A         IA+++K  LD+++G  W V+V    Y  +LSHE  + IH  + + +  +WK P
Sbjct:  236 SKKVMSLDFLKTFEEIDGDFSGEISYEEISTYMRRHNFEAEFVDKWLTLFEPNKDGRITIESYCGSLGLIPREHYYGRVVANRKVGSLIPRGNATEDWANVRIIRLEPLMDDTMKTFIIRLARKAQKELATEYEIARFIKQSLDLRWGGLWQVIVSRYPYACYLSHEMASLIHFWLLEHSFCIWKTP 422
[Close]
BLAST of Dynein light chain vs. Planmine SMEST
Match: SMESG000048100.1 (SMESG000048100.1)

HSP 1 Score: 119.398 bits (298), Expect = 4.071e-31
Identity = 55/67 (82.09%), Postives = 59/67 (88.06%), Query Frame = 1 
Query:  355 MEFIKAFEEIDSDNSGEITRGELIRYMRLKNYKPAFVEKWLNIFDADNSGTITLEEFCNTLGLIPNK 555
            MEFIKAFEEID D SGEITRGEL  YM+ KNYKPAFVEKW+ IFD DNSGTI+LEEFC+TLGLIP K
Sbjct:    1 MEFIKAFEEIDKDESGEITRGELEEYMKAKNYKPAFVEKWMRIFDIDNSGTISLEEFCSTLGLIPGK 67

HSP 2 Score: 83.1889 bits (204), Expect = 6.201e-18
Identity = 34/90 (37.78%), Postives = 57/90 (63.33%), Query Frame = 1 
Query:  625 PLYDLYVIDEDPLNDPKFKDFCMKICQEATNNENDFISIAKYLKSVLDVKFGRSWNVVVDIDAYGSFLSHEPGAFIHIKVRKFAILLWKV 894
            P  ++YVI EDP      ++F + +  ++    N+ + +AK +K +LD  F RSW+VV   DAYG  ++HE G FIH++ R++ IL+W++
Sbjct:  226 PSDEIYVISEDPDMTESLRNFVLNLSLDSARRFNEPLEMAKCIKRILDFTFNRSWHVVTGKDAYGCLVTHEEGRFIHVRAREWGILMWQI 315
[Close]
BLAST of Dynein light chain vs. Planmine SMEST
Match: SMESG000026622.1 (SMESG000026622.1)

HSP 1 Score: 97.4413 bits (241), Expect = 2.653e-24
Identity = 61/178 (34.27%), Postives = 90/178 (50.56%), Query Frame = 1 
Query:  361 FIKAFEEIDSDNSGEITRGELIRYMRLKNYKPAFVEKWLNIFDADNSGTITLEEFCNTLGLIPNKNYQXXXXXXXXXXXXXXXXXXXXPLYDLYVIDEDPLNDPKFKDFCMKICQEATNNENDFISIAKYLKSVLDVKFGRSWNVVVDIDAYGSFLSHEPGAFIHIKVRKFAILLWKV 894
            F+ AF  IDSD S EIT  EL +YMRL N K AFV+KW+NIFD+++ G ITL+E+C+ LGL+ N+    R +       + K     + +    V  E  +     +      CQ A         ++K++K  LD  +G SW+ V  +  + S+ S  P      K  K+  L+WK 
Sbjct:    4 FLTAFFNIDSDQSEEITIAELEKYMRLNNLKDAFVKKWINIFDSNDDGVITLDEYCSVLGLVTNEARIMREQFNIEHSAIPKTLPDDVKIIQSSVTSEMEIEMVDIEINGWSKCQNAPQ-------VSKFIKEELDKAYGPSWHCVTVLGQFWSYFSSAPATSFQYKRGKYIYLIWKT 174
The following BLAST results are available for this feature:
BLAST of Dynein light chain vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Dynein light chain vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 1
Match NameE-valueIdentityDescription
dlc-25.821e-731.71Probable dynein light chain 2, cytoplasmic [Sourc... [more]
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BLAST of Dynein light chain vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Dynein light chain vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Dynein light chain vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Dynein light chain vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Dynein light chain vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 2
Match NameE-valueIdentityDescription
sp|P14202|TEGU_SCHMA7.487e-1631.52Tegument antigen OS=Schistosoma mansoni OX=6183 GN... [more]
sp|Q21557|DYL2_CAEEL7.404e-631.71Probable dynein light chain 2, cytoplasmic OS=Caen... [more]
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BLAST of Dynein light chain vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A267EIW96.318e-4044.02Dynein light chain OS=Macrostomum lignano OX=28230... [more]
A0A1I8I7N84.139e-3944.02Dynein light chain OS=Macrostomum lignano OX=28230... [more]
A0A1I8IZR31.818e-3744.32Uncharacterized protein OS=Macrostomum lignano OX=... [more]
A0A1I8IZM21.703e-3543.58Uncharacterized protein OS=Macrostomum lignano OX=... [more]
A0A1I8ITI71.151e-3343.65Uncharacterized protein OS=Macrostomum lignano OX=... [more]
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BLAST of Dynein light chain vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Dynein light chain vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Dynein light chain vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 1
Match NameE-valueIdentityDescription
DYN22.419e-732.00Cytoplasmic light chain dynein, microtubule motor ... [more]
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BLAST of Dynein light chain vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Dynein light chain vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Dynein light chain vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000042102.11.062e-114100.00SMESG000042102.1[more]
SMESG000008592.19.172e-4440.43SMESG000008592.1[more]
SMESG000078154.16.647e-3234.22SMESG000078154.1[more]
SMESG000048100.14.071e-3182.09SMESG000048100.1[more]
SMESG000026622.12.653e-2434.27SMESG000026622.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30027878 ID=SMED30027878|Name=Dynein light chain|organism=Schmidtea mediterranea sexual|type=transcript|length=967bp
AAAAACTATTTCACAATCATCACCATTTGTTTAAATAAAGAATTTGTTTC
AGCTTCCTTTTTCTAGAAAAGTCTAAAACGAAAATTCTTGGTGCCTGATC
GATGCCAAACGGAGCACACAAGACGAAATCTAATCTCAATCATTGTCTGT
CTCCGTGATGTAATTACCTGAACAATTCATTACATTTTCTATTTGATTTC
CAATCAAATAATAGAAACGGCAGTGTGCAAAAATTTCAGTGCTCAATTTT
TAAACTGGCATTAAAAAGAACTTGTTTAAATATTGATCGGAAGATTTTGA
TATTTATATTAGAGTTTTGAAATTGTTTCATTTTTTACAACTCATTGTTT
TTCAATGGAGTTTATCAAAGCTTTTGAAGAAATTGATTCGGATAATTCCG
GAGAAATTACAAGAGGAGAGTTGATTCGTTATATGAGGCTCAAAAATTAC
AAACCAGCTTTTGTCGAGAAATGGCTGAATATATTTGATGCAGATAATTC
CGGTACAATAACACTCGAAGAGTTTTGCAATACGCTAGGACTTATTCCAA
ATAAAAATTATCAAAAAAGAATAGAGAAACGTAAATCAGAAAAAGAATTA
TTAAAAAGAAAGAGCCTCCTTATTCCTTTATACGATCTCTATGTCATTGA
CGAAGATCCTTTAAATGACCCAAAGTTCAAAGACTTTTGCATGAAAATTT
GCCAAGAGGCTACTAACAATGAAAATGATTTTATTTCAATTGCAAAATAC
CTTAAATCAGTATTAGATGTAAAATTCGGAAGGTCATGGAATGTCGTTGT
TGATATTGATGCATATGGATCATTTTTGAGTCACGAACCTGGAGCTTTTA
TTCATATAAAAGTTAGAAAATTCGCCATTTTACTGTGGAAGGTTCCAGCA
GAAGAATAAAATATATTTTCTTCAATATTTATTTTTTTCACCGAGTTTAC
AAAATAAAGAAAATTTC
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protein sequence of SMED30027878-orf-1

>SMED30027878-orf-1 ID=SMED30027878-orf-1|Name=SMED30027878-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=185bp
MEFIKAFEEIDSDNSGEITRGELIRYMRLKNYKPAFVEKWLNIFDADNSG
TITLEEFCNTLGLIPNKNYQKRIEKRKSEKELLKRKSLLIPLYDLYVIDE
DPLNDPKFKDFCMKICQEATNNENDFISIAKYLKSVLDVKFGRSWNVVVD
IDAYGSFLSHEPGAFIHIKVRKFAILLWKVPAEE*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: molecular function
TermDefinition
GO:0003774motor activity
GO:0005509calcium ion binding
Vocabulary: cellular component
TermDefinition
GO:0005737cytoplasm
GO:0005856cytoskeleton
GO:0005874microtubule
GO:0030286dynein complex
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000020protonephridia
PLANA:0000034epidermis
PLANA:0000141dorsal region of the whole animal
Vocabulary: INTERPRO
TermDefinition
IPR037177DLC_sf
IPR002048EF_hand_dom
IPR001372Dynein_light_chain_typ-1/2
IPR011992EF-hand-dom_pair
IPR018247EF_Hand_1_Ca_BS
Vocabulary: biological process
TermDefinition
GO:0007017microtubule-based process
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
NoneNo IPR availableCOILSCoilCoilcoord: 66..86
NoneNo IPR availableGENE3DG3DSA:1.10.238.10coord: 1..89
e-value: 4.4E-14
score: 54.3
IPR002048EF-hand domainSMARTSM00054efh_1coord: 2..30
e-value: 4.4E-4
score: 29.6
coord: 36..64
e-value: 0.005
score: 26.1
IPR002048EF-hand domainPFAMPF13499EF-hand_7coord: 5..59
e-value: 3.5E-10
score: 40.2
IPR002048EF-hand domainPROSITEPS50222EF_HAND_2coord: 1..33
score: 12.087
IPR002048EF-hand domainPROSITEPS50222EF_HAND_2coord: 37..67
score: 10.273
IPR002048EF-hand domainCDDcd00051EFhcoord: 2..58
e-value: 6.28093E-12
score: 56.0169
IPR001372Dynein light chain, type 1/2SMARTSM01375Dynein_light_2coord: 90..180
e-value: 4.9E-11
score: 52.7
IPR001372Dynein light chain, type 1/2PFAMPF01221Dynein_lightcoord: 107..179
e-value: 5.5E-17
score: 61.9
IPR037177Dynein light chain superfamilyGENE3DG3DSA:3.30.740.10coord: 100..180
e-value: 4.6E-15
score: 57.3
IPR018247EF-Hand 1, calcium-binding sitePROSITEPS00018EF_HAND_1coord: 11..23
IPR018247EF-Hand 1, calcium-binding sitePROSITEPS00018EF_HAND_1coord: 45..57
IPR011992EF-hand domain pairSUPERFAMILYSSF47473EF-handcoord: 2..151