A disintegrin and metalloproteinase with thrombospondin motifs

Overview
NameA disintegrin and metalloproteinase with thrombospondin motifs
Smed IDSMED30027813
Length (bp)5007
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of A disintegrin and metalloproteinase with thrombospondin motifs (SMED30027813) t-SNE clustered cells

Violin plots show distribution of expression levels for A disintegrin and metalloproteinase with thrombospondin motifs (SMED30027813) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of A disintegrin and metalloproteinase with thrombospondin motifs (SMED30027813) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for A disintegrin and metalloproteinase with thrombospondin motifs (SMED30027813) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30027813

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 10

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
muscle cellSMED30027813SMESG000038885.1 dd_Smed_v4_10259_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymaSMED30027813SMESG000038885.1 Contig38164newmark_estsPMID:27612384
Roberts-Galbraith et al., 2016		whole organism asexual adult colorimetric in situ hybridization evidence
parenchymaSMED30027813SMESG000038885.1 Contig38164uc_Smed_v2PMID:27612384
Roberts-Galbraith et al., 2016		whole organism asexual adult colorimetric in situ hybridization evidence
protonephridiaSMED30027813SMESG000038885.1 Contig12938newmark_estsPMID:27612384
Roberts-Galbraith et al., 2016		whole organism asexual adult colorimetric in situ hybridization evidence
protonephridiaSMED30027813SMESG000038885.1 Contig12938uc_Smed_v2PMID:27612384
Roberts-Galbraith et al., 2016		whole organism asexual adult colorimetric in situ hybridization evidence
eyeSMED30027813SMESG000038885.1 Contig12938newmark_estsPMID:27612384
Roberts-Galbraith et al., 2016		whole organism asexual adult colorimetric in situ hybridization evidence
eyeSMED30027813SMESG000038885.1 Contig12938uc_Smed_v2PMID:27612384
Roberts-Galbraith et al., 2016		whole organism asexual adult colorimetric in situ hybridization evidence
secretory cellSMED30027813SMESG000038885.1 Contig12938newmark_estsPMID:27612384
Roberts-Galbraith et al., 2016		whole organism asexual adult colorimetric in situ hybridization evidence
secretory cellSMED30027813SMESG000038885.1 Contig12938uc_Smed_v2PMID:27612384
Roberts-Galbraith et al., 2016		whole organism asexual adult colorimetric in situ hybridization evidence
muscle cellSMED30027813SMESG000038885.1 dd_Smed_v4_10259_0_1dd_Smed_v4PMID:30962434
Cote et al., 2019		whole organism asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
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BLAST of A disintegrin and metalloproteinase with thrombospondin motifs vs. Ensembl Human
Match: ADAMTS20 (ADAM metallopeptidase with thrombospondin type 1 motif 20 [Source:HGNC Symbol;Acc:HGNC:17178])

HSP 1 Score: 366.311 bits (939), Expect = 2.232e-102
Identity = 375/1415 (26.50%), Postives = 575/1415 (40.64%), Query Frame = 1 
Query:  271 GVFQWDNKLWFIKPNTKTKFNSKFLKTEMNFLPHKIYFTALN--LNKPLFSCKL---------LKNNGYRNIPQESHF--SRVFQRMKRETYPVVDSE--------IVEPNIIELLIVVTSNFVKRFKKDFRQYILSNVAIATKLLHDPTIKASITXXXXXXXXXXEDYERNNDLHDWSLLSQDRVVSRFCHWVRQKKQLWNYS---WDSAILIN-DGVFSS----NAIGIAHLRSMCND-NNCLAVVDRGFGTGFIIAHELAHQMNARHDFDNAEACSFFEKQYDNKTKYNTIMSTSLFFEYYPFIWSVCSQNVINSFLKSKYSFCLKQRNRHRNLYPHEQINEFFQKYSTGVDYDLNEQCSFAFGEKSEFCETDQNSRKKCSVLYCRL--KRYPICLRADAIIADGTECDVNQHCINGKCLYKNITIAPIDGGWSEYSEWSNCSRPCNGGVQFSYRTCDNPVPADGGRFCTGTKERIRSCNIEECSSFS-DPREESCGKYNLKPY----IPTNDEEFP----------CNLVC--ITTNHSLKYDISLTDGTPCSPFRSDICVKGTCYKTGCDRIVGSKKAIDNCNICAGQNDTCFKKESFFDGSKVAKVRMIRAFRIPPNVYNLFIKKVSQRMTPFTDEVY---DDFELLLVVNRRTVIRRSETIEPLAGGQ--LRYSGSKNKVETISIKGKLNVGISIVIKVENTKTTLNLPFISYHYFV-----KDIFVWKYLEVITHPCKDQCGGFIEISPACFKKRDNQRYVDHYCSKATKPEPKIIKCGAICGYRWQRATEHYINSTVNKSCPIRCGTGKVKIPFVCQKINNQDDNNSLWETVEENLCFAVDLVDRPIEELNCVGQCNPLLWSYGKWEECPIECGTTFRYRNFICKDNKGLEWQKEWCERHLGLPDNKETCLSFNNCRNLTRWVTSPWSRCSNSCESELQKRMVYCFRSEKSDEILDEKFLKIHEQISDAFCDIHSPKPITERPCSLNSCYFWIXXXXXXXXXXXXLGFRIQSHECKKKFNKNHEMITVDDKFCLKQNLVKPLDVRMRCFLKKCAIES----------------FWIEMEWSKCSVSCGEGLQYRSLKCGYENENKTLTTWDNNEMCKNKMVPVSIQICKVTPCPKWIYSEWSECEGTCEYGSQHRTVLCTD---PISE-------QILPDSKCDIK------NKFP----------------------NFQKCLLSKLCG-HWIVGKWSQCSASCGLGVKTRTITCNYSNGSKSIDHSVCKSVA-PFEEIHCQVKPCSTNAFWWLVKPSECYEYNCQPGIMYAHVRCVNRKFQVLYDSKCSRIKHPSYYVGCLNTTC-RRYFWTAESWDNIPCPDISCTMKIRNRDVYCVDDYGNIQKDAMCDQSDKPDTWRLCPS 4167
            G F+  N  +F++P  K   N      + +  PH IY   LN    + L  C +         L  + Y N+ ++ +    RV     +   P+ D          I  P  IE+++   +  V     + + YIL+ ++I   +  DP+I   I I VV +V++  + E      D +       +  FC W + +  L +      D+A+LI  + + SS    N +G+++L ++C+   +C    ++G  + F IAHEL H +  +HD DN              TKY+ +M+ +L F   P+ WS CS+  +  FL + Y  CL  +       P E+I     +   G  YD N+QC  AFG  S+ C         C  L+C    K +  C       ADGT+C    HC +G C+ K     P++G W  +  +S+CSR C GG++ + R C+ P P +GG +C G + + RSCN + C   + D RE+ C  +N K      IP+N    P          C L C    TN+       + DGTPC     DICV+G C   GCD ++ S   ID C +C G N +C      F+ S      ++   +IP    N+ I++ S    P  D+ Y    D E   + N   ++  S+    + G +  + YSGS N VE I+   +      ++++V       N P + Y + +      D+F W         C   C G    +  C  K D+    D  C     P      C   C  RW     H I  +    C  +CG G   +   C K +  +      +TV+ +  +  D +  P +EL C G C    W Y +W +C   CG   R R   C +N G       C+    +   +E C  F    +   W  S WS C  +C    ++R V+C              L + + +SD FC+  S KP +  PC L++C  W     G C+  CG G++++  +C  +         ++D  C + +  +P D R  C L  C+  S                 W    W+ CSVSCG G Q R + C        L    +   C +   P  I  C  TPC +W   +WS C  +C +G   R VLC +   PI E       + L + +C +       + FP                      N  + +   + G  W  G W  CS+SC  G++ R + C   NG  +   S C + + P E   C   PC     W      EC +  C  GI    V C     Q+L D  C  +  P   + C    C     W  E W +      SC    + R+V+C+D +    +D  C Q  KP T + C S
Sbjct:  153 GTFKGQNGEYFLEPIMKADGNEY---EDGHNKPHLIYRQDLNNSFLQTLKYCSVSESQIKETSLPFHTYSNMNEDLNVMKERVLGHTSKNV-PLKDERRHSRKKRLISYPRYIEIMVTADAKVVSAHGSNLQNYILTLMSIVATIYKDPSIGNLIHIVVVKLVMIHREEEGPVINFDGAT-----TLKNFCSWQQTQNDLDDVHPSHHDTAVLITREDICSSKEKCNMLGLSYLGTICDPLQSCFINEEKGLISAFTIAHELGHTLGVQHD-DNPRCKEM------KVTKYH-VMAPALSFHMSPWSWSNCSRKYVTEFLDTGYGECLLDK-------PDEEIYNLPSELP-GSRYDGNKQCELAFGPGSQMCP----HINICMHLWCTSTEKLHKGCFTQHVPPADGTDCGPGMHCRHGLCVNKETETRPVNGEWGPWEPYSSCSRTCGGGIESATRRCNRPEPRNGGNYCVGRRMKFRSCNTDSCPKGTQDFREKQCSDFNGKHLDISGIPSNVRWLPRYSGIGTKDRCKLYCQVAGTNYFYLLKDMVEDGTPCGTETHDICVQGQCMAAGCDHVLNSSAKIDKCGVCGGDNSSCKTITGVFNSSHYGYNVVV---KIPAGATNVDIRQYSYSGQP--DDSYLALSDAEGNFLFNGNFLLSTSKKEINVQGTRTVIEYSGSNNAVERINSTNRQEK--ELILQVLCVGNLYN-PDVHYSFNIPLEERSDMFTWDPYGPW-EGCTKMCQGLQRRNITCIHKSDHSVVSDKECDHLPLPSFVTQSCNTDCELRW-----HVIGKS---ECSSQCGQGYRTLDIHCMKYSIHEG-----QTVQVDDHYCGDQLKPPTQEL-CHGNCVFTRWHYSEWSQCSRSCGGGERSRESYCMNNFGHRLADNECQELSRV--TRENCNEF----SCPSWAASEWSECLVTCGKGTKQRQVWC-------------QLNV-DHLSDGFCN-SSTKPESLSPCELHTCASWQVGPWGPCTTTCGHGYQMRDVKCVNELAS----AVLEDTECHEAS--RPSD-RQSCVLTPCSFISKLETALLPTVLIKKMAQWRHGSWTPCSVSCGRGTQARYVSC-----RDALDRIADESYCAHLPRPAEIWDC-FTPCGEWQAGDWSPCSASCGHGKTTRQVLCMNYHQPIDENYCDPEVRPLMEQECSLAACPPAHSHFPSSPVQPSYYLSTNLPLTQKLEDNENQVVHPSVRGNQWRTGPWGSCSSSCSGGLQHRAVVCQDENGQSA---SYCDAASKPPELQQCGPGPCPQ---WNYGNWGECSQ-TCGGGIKSRLVICQFPNGQILEDHNCEIVNKPPSVIQCHMHACPADVSWHQEPWTSC---SASCGKGRKYREVFCIDQFQRKLEDTNCSQVQKPPTHKACRS 1471

HSP 2 Score: 166.777 bits (421), Expect = 1.505e-40
Identity = 214/863 (24.80%), Postives = 336/863 (38.93%), Query Frame = 1 
Query: 2209 SIVIKVENTKTTLNLPFISYHYFVKDIFVWKYLEVITHPCKDQCGGFIEISPACFKKRDNQRYVDHYCSKATKPEPKIIKCGAICGYRWQRATEHYINSTVNKSCPIRCGTGKVKIPFVCQKINNQDDNNSLWETVEENLCFAVDLVDRPIEELNC-VGQCNPLLWSYGKWEECPIECGTTFRYRNFICKDNKGLEWQKEWCERHLGLPDNKETCLSFNNCRNLTRWVTSPWSRCSNSCESELQKRMVYCFRSEKSDEILDEKFLKIHEQISDAFCDIHSPKPITERPCSLNSCYFWIXXXXXXXXXXXXLGFRIQSHECKKKFNKNHEMITVDDKFCLKQNLVKPLDVRMRCFLKKCAIESFWIEMEWSKCSVSCGEGLQYRSLKCGYENENKTLTTWDNNEMCKNKMVPVSIQICKVTPCPKWIYSEWSECEGTCEYGSQHRTVLCTDPISEQILPDSKCDIKNKFPNFQKCLLSKLCGHWIVGKWS-QCSASCGLGVKTRTITCNYSNGSKSIDHSVCKSVAPFEEIHCQVKPCSTNAFWWLVKPSECYEYNCQPGIMYAHVRCVN---------RKFQVLYDSKCSRIKHPSYYVGCLNTTCRRYFWTAESWDNIPCPDISCTMKIRNRDVYCVDDYGNIQKDAMCDQSDKPDTWRLCPSPQNCSNIPRSCKELKSRQSVSKDGEYSLAIDLNWAYFIYCADMNTEEPKEYLTL--RELNYARTSKYVSTDVSSCIYEEEMEFNQKCPTCKINENLWSITYYNKIRINLSDLSIDVMDDRFSATNGQSFIPFGTAKDCAGSTSCPKGHFKINLRGTGFSVSMETRWNEVYPKYGYRILRKQTSQIVKGWCGGHCSGCSP 4758
            S + K+E    T  LP +     +K +  W++      PC   CG   +      +   ++   + YC+   +P  +I  C   CG  WQ              C   CG GK     +C   +         + ++EN C   D   RP+ E  C +  C P   ++  +   P++        ++    N  L  + E  E  +  P  +             +W T PW  CS+SC   LQ R V C      DE             S ++CD  S KP   + C    C  W     G+CS  CG G + +   C+    +      ++D  C   N  KP  V ++C +  C  +  W +  W+ CS SCG+G +YR + C  + + K   T      C     P + + C+   CP W  + W+EC  TC  G Q R V C      Q++ +  CD   +  + ++C       H  + +    CS SC      + + C  +   +  +     S       +C+  PC  N        S+C   NC          C            + + +   +C  +     Y  C+N+      W    W       ++C + I  R V C+  +G +  D +C    KP   + C +  +C +   +CKE++ +  + KDG+Y L I       IYCADM  E PKEYLTL   E N++    +   +   C +      + +C    +       T ++KIRI+L+ + I   D  FS T   + +PF TA DC  +  CP+G F INL GTG  +S   +W          I R +      G CGG+C  C P
Sbjct: 1135 SFISKLE----TALLPTV----LIKKMAQWRHGSWT--PCSVSCGRGTQARYVSCRDALDRIADESYCAHLPRPA-EIWDCFTPCG-EWQAGDW--------SPCSASCGHGKTTRQVLCMNYH---------QPIDENYC---DPEVRPLMEQECSLAACPP---AHSHFPSSPVQ-------PSYYLSTNLPLTQKLEDNENQVVHPSVRGN-----------QWRTGPWGSCSSSCSGGLQHRAVVC-----QDE----------NGQSASYCDAAS-KPPELQQCGPGPCPQWNYGNWGECSQTCGGGIKSRLVICQFPNGQ-----ILEDHNCEIVN--KPPSV-IQCHMHACPADVSWHQEPWTSCSASCGKGRKYREVFCIDQFQRKLEDT-----NCSQVQKPPTHKACRSVRCPSWKANSWNECSVTCGSGVQQRDVYCRLKGVGQVV-EEMCDQSTRPCSQRRCWSQDCVQHKGMERGRLNCSTSCERKDSHQRMECTDNQIRQVNEIVYNSSTISLTSKNCRNPPC--NYIVVTADSSQCAN-NCGFSYRQRITYCTEIPSTKKHKLHRLRPIVYQECPVVPSSQVYQ-CINSCLHLATWKVGKWSKC---SVTCGIGIMKRQVKCITKHG-LSSD-LCLNHLKPGAQKKCYA-NDCKSF-TTCKEIQVKNHIRKDGDYYLNIK-GRIIKIYCADMYLENPKEYLTLVQGEENFSEVYGFRLKNPYQCPFNGSRREDCECDNGHLAAGY---TVFSKIRIDLTSMQIKTTDLLFSKTIFGNAVPFATAGDCYSAFRCPQGQFSINLSGTGMKISSTAKWLTQGSYTSVSIRRSEDGTRFFGKCGGYCGKCLP 1899

HSP 3 Score: 95.5153 bits (236), Expect = 7.677e-19
Identity = 144/575 (25.04%), Postives = 219/575 (38.09%), Query Frame = 1 
Query: 2656 PIEELNCVGQCNPLLWSYGKWEECPIECGTTFRYRNFIC--KDNKGLEWQKEWCERHLGLPD-NKETCLSFNNCRNLTRWVTSPWSRCSNSCESELQKRMVYCFRSEKSDEILDEKFLKIHE----QISDAFCDIHSPKPITERPCSLNSCYF--WIXXXXXXXXXXXXLGFRIQSHECKKKFNKNHEMITVDDKFCLKQNLVKPLDVRMRCFLKKCAIESFWIEMEWSKCSVSCGEGLQYRSLKCGYENENKTLTTWDNNEMCKNKMVPVSIQICKVTPCPKWIYSEWSECEGTCEYGSQHRTVLCTDPISEQILPDSKCDIKNKFPNFQKCLLS------------------KLCGHWIVGKWSQCSASCGLGVKTRTITCNYSNGSKSIDHSVCKSVAPFEEIHCQVKPCSTNAFWWLVKPSECYEYNCQPGIMYAHVRCVN-----------RKFQVLYDSKCSRIK-------------HPSYYVG---------------CLNTTCRRYFWTAESWDNIPCPDISCTMKIRNRDVYCVDDYGNIQKDAMCDQSDKPDTWRLC---PSPQ 4173
            P+EE + +   +P    YG WE C   C    + RN  C  K +  +   KE C+ HL LP    ++C    N     RW     S CS+ C    +   ++C +              IHE    Q+ D +C     KP T+  C  N C F  W  S+  +CS  CG G R +   C   F        + D  C + + V     R  C    C     W   EWS+C V+CG+G + R + C    ++ +      +  C +   P S+  C++  C  W    W  C  TC +G Q R V C + ++  +L D++C   ++  + Q C+L+                  K    W  G W+ CS SCG G + R ++C  +   +  D S C  +    EI     PC     W     S C   +C  G     V C+N            + + L + +CS                 PSYY+                 ++ + R   W    W +      SC+  +++R V C D+ G  Q  + CD + KP   + C   P PQ
Sbjct:  840 PLEERSDMFTWDP----YGPWEGCTKMC-QGLQRRNITCIHKSDHSVVSDKE-CD-HLPLPSFVTQSC----NTDCELRWHVIGKSECSSQCGQGYRTLDIHCMK------------YSIHEGQTVQVDDHYCG-DQLKPPTQELCHGN-CVFTRWHYSEWSQCSRSCGGGERSRESYCMNNFGHR-----LADNECQELSRV----TRENCNEFSCP---SWAASEWSECLVTCGKGTKQRQVWCQLNVDHLS------DGFCNSSTKPESLSPCELHTCASWQVGPWGPCTTTCGHGYQMRDVKCVNELASAVLEDTECHEASRPSDRQSCVLTPCSFISKLETALLPTVLIKKMAQWRHGSWTPCSVSCGRGTQARYVSCRDAL-DRIADESYCAHLPRPAEIWDCFTPCGE---WQAGDWSPC-SASCGHGKTTRQVLCMNYHQPIDENYCDPEVRPLMEQECSLAACPPAHSHFPSSPVQPSYYLSTNLPLTQKLEDNENQVVHPSVRGNQWRTGPWGSC---SSSCSGGLQHRAVVCQDENG--QSASYCDAASKPPELQQCGPGPCPQ 1361
[Close]
BLAST of A disintegrin and metalloproteinase with thrombospondin motifs vs. Ensembl Human
Match: ADAMTS9 (ADAM metallopeptidase with thrombospondin type 1 motif 9 [Source:HGNC Symbol;Acc:HGNC:13202])

HSP 1 Score: 359.377 bits (921), Expect = 4.244e-100
Identity = 334/1331 (25.09%), Postives = 530/1331 (39.82%), Query Frame = 1 
Query:  436 NGYRNIPQESHFSRVFQRMKRETYPVVDSEIVEPNIIELLIVVTSNFVKRFKKDFRQYILSNVAIATKLLHDPTIKASITXXXXXXXXXXEDYERNNDLHDWSLLSQDRVVSRFCHWVRQKKQLWNYSWDSAILINDGVF-----SSNAIGIAHLRSMCND-NNCLAVVDRGFGTGFIIAHELAHQMNARHDFDNAEACSFFEKQYDNKTKYNTIMSTSLFFEYYPFIWSVCSQNVINSFLKSKYSFCLKQRNRHRNLYPHEQINEFFQKYSTGVDYDLNEQCSFAFGEKSEFCETDQNSRKKCSVLYCRLKR--YPICLRADAIIADGTECDVNQHCINGKCLYKNITIAPIDGGWSEYSEWSNCSRPCNGGVQFSYRTCDNPVPADGGRFCTGTKERIRSCNIEEC-SSFSDPREESCGKYNLKPY----IPTNDEEFP----------CNLVCITTNHSLKYDI--SLTDGTPCSPFRSDICVKGTCYKTGCDRIVGSKKAIDNCNICAGQNDTCFKKESFFDGSKVAKVRMIRAFRIPPNVYNLFIKKVSQRMTPFTDEVYDDFELLLVVNRRTVIRRSETIEPLAGGQLR-------YSGSKNKVETIS----IKGKLNVGISIVIKVEN--TKTTLNLPF--ISYHYFVKDIFVWKYLEVITHPCKDQCGGFIEISPACFKKRDNQRYVDHYCSKATKPEPKIIKCGAICGYRWQRATEHYINSTVNKSCPIRCGTGKVKIPFVCQKINNQDDNNSLWETVEENLCFAVDLVDRPIEELNCVGQCNPLLWSYGKWEECPIECGTTFRYRNFICKDNKGLEWQKEWCERHLGLPDNKETCLSFNNCRNLTRWVTSPWSRCSNSCESELQKRMVYCFRSEKSDEILDEKFLKIHEQISDAFCDIHSPKPITERPCSLNSCYFWIXXXXXXXXXXXXLGFRIQSHECKKKFNKNHEMITVDDKFCLKQNLVKPLDVRMRCFLKKC---------------AIESFWIEMEWSKCSVSCGEGLQYRSLKCGYENENKTLTTWDNNEMCKNKMVPVSIQICKVTPCPKWIYSEWSECEGTCEYGSQHRTVLCTDPISEQILPDSKCDIKNKFPNFQKCLL---------SKLCGH------------------------WIVGKWSQCSASCGLGVKTRTITCNYSNGSKSIDHSVCKSVAPFEEIHCQVKPCSTNAFWWLVKPSECYEYNCQPGIMYAHVRCVNRKFQVLYDSKCSRIKHPSYYVGCLNTTC-RRYFWTAESWDNIPCPDISCTMKIRNRDVYCVDDYGNIQKDAMCDQSDKPDTWRLC 4161
            + Y N    +   R  +R KR         +  P  +E+L+V  +  V    ++ + YIL+ ++I   +  DP+I   I I +V+++++  +     D    S  +Q   +  FC W   K        D+A+L+            + +G+A L ++C+   +C    D G  T F IAHEL H  N  HD +N       + + +       +M+ +L F   P++WS CS+  I  FL + Y  CL      R  YP             G+ Y++N+QC   FG  S+ C        +C  L+C      +  C       ADGTEC+  +HC  G C+ K + +   DG W  +S +  CSR C GG++ + R C+ P P +GG++C G + + +SCN E C     D R+E C  ++ K +    +  N    P          C L C    ++  Y +   + DGTPC    +DICV+G C + GCD ++ SK   D C +C G N +C      F+        ++   RIP    N+ +++ S     F+ E  DD  L L  ++   +     +  +A  ++R       YSGS+  VE I+    I+ +L + +  V K+ N   + + N+P       ++      W+        C   C G  +    C ++ D     D  C +  +P      CG  C  RW  A+           C  +CG G   +   C K +  D      E V++  C +     +P     C G+CN   W Y  W EC   C    + R  IC + +        C     +    + C  F       +W +  WS C  +C    + R V+C   E              ++++D  CD  + KP + + C    C  W     G+CS  CG G+++++ +C         M  VDD  C      +P D +  C L  C               A  + W    W+ CS +CG+G + R + C   +EN ++    +   C     PV+ + C VTPC +W   +WS C  TC  G   R V+C +  S+ ++  S+CD        Q C +         S L  H                        W  G W  CS++C  G + R + C   NG  + D    + + P E+  C+  PC     W      EC +  C  GI    V C     +   D  C  +  P     C    C     W+   W +     +SC    + R+VYC+   G+  +   C    KP   R C
Sbjct:  267 SAYGNKTDNTREKRTHRRTKRF--------LSYPRFVEVLVVADNRMVSYHGENLQHYILTLMSIVASIYKDPSIGNLINIVIVNLIVIHNE----QDGPSISFNAQT-TLKNFCQWQHSKNSPGGIHHDTAVLLTRQDICRAHDKCDTLGLAELGTICDPYRSCSISEDSGLSTAFTIAHELGHVFNMPHDDNN-------KCKEEGVKSPQHVMAPTLNFYTNPWMWSKCSRKYITEFLDTGYGECLLNEPESRP-YP-------LPVQLPGILYNVNKQCELIFGPGSQVCPY----MMQCRRLWCNNVNGVHKGCRTQHTPWADGTECEPGKHCKYGFCVPKEMDVPVTDGSWGSWSPFGTCSRTCGGGIKTAIRECNRPEPKNGGKYCVGRRMKFKSCNTEPCLKQKRDFRDEQCAHFDGKHFNINGLLPNVRWVPKYSGILMKDRCKLFCRVAGNTAYYQLRDRVIDGTPCGQDTNDICVQGLCRQAGCDHVLNSKARRDKCGVCGGDNSSCKTVAGTFNTVHYGYNTVV---RIPAGATNIDVRQHS-----FSGETDDDNYLALSSSKGEFLLNGNFVVTMAKREIRIGNAVVEYSGSETAVERINSTDRIEQELLLQVLSVGKLYNPDVRYSFNIPIEDKPQQFYWNSHGPWQ-------ACSKPCQGERKRKLVCTRESDQLTVSDQRCDRLPQPGHITEPCGTDCDLRWHVASR--------SECSAQCGLGYRTLDIYCAKYSRLDGKT---EKVDDGFCSS---HPKPSNREKCSGECNTGGWRYSAWTECSKSCDGGTQRRRAICVNTRNDVLDDSKCTHQEKV--TIQRCSEF----PCPQWKSGDWSECLVTCGKGHKHRQVWCQFGE--------------DRLNDRMCDPET-KPTSMQTCQQPECASWQAGPWGQCSVTCGQGYQLRAVKCI----IGTYMSVVDDNDC--NAATRPTDTQ-DCELPSCHPPPAAPETRRSTYSAPRTQWRFGSWTPCSATCGKGTRMRYVSC--RDENGSVA---DESACATLPRPVAKEECSVTPCGQWKALDWSSCSVTCGQGRATRQVMCVN-YSDHVIDRSECDQDYIPETDQDCSMSPCPQRTPDSGLAQHPFQNEDYRPRSASPSRTHVLGGNQWRTGPWGACSSTCAGGSQRRVVVCQDENGYTAND--CVERIKPDEQRACESGPCPQ---WAYGNWGECTKL-CGGGIRTRLVVCQRSNGERFPDLSCEILDKPPDREQCNTHACPHDAAWSTGPWSSC---SVSCGRGHKQRNVYCMAKDGSHLESDYCKHLAKPHGHRKC 1493

HSP 2 Score: 206.453 bits (524), Expect = 1.241e-52
Identity = 199/802 (24.81%), Postives = 324/802 (40.40%), Query Frame = 1 
Query: 2521 CPIRCGTGKVKIPFVCQKINNQDDNNSLWETVEENLCFAVDLVDRPIEELNC-VGQCNPLLWSYGKWEECPIECGTTFRYRNFICKDNKGLEWQKEWCERHLGLPDNKETCLSFNNCRNLT-------------------------------RWVTSPWSRCSNSCESELQKRMVYCFRSEKSDEILDEKFLKIHEQISDAFCDIHSPKPITERPCSLNSCYFWIXXXXXXXXXXXXLGFRIQSHECKKKFNKNHEMITVDDKFCLKQNLVKPLDVRMRCFLKKCAIESFWIEMEWSKCSVSCGEGLQYRSLKCGYENENKTLTTWDNNEMCKNKMVPVSIQICKVTPCPKWIYSEWSECEGTCEYGSQHRTVLCTDPISEQILPDSKCDIKNKFPNFQKCLLSKLCGH-WIVGKWSQCSASCGLGVKTRTITCNYSNGSKSIDHSVCKSVAPFEEIHCQVKPCSTNAFWWLVKPSECYEYNCQPGIMYAHVRCV-------NRKFQVLYDSKCSRIKHPSYYVGCLNTTCRRYFWTAESWDNIPCPDISCTMKIRNRDVYCVDDYGNIQKDAMCDQSDKPDTWRLCPSPQNCSNIPRSCKELKSRQSVSKDGEYSLAIDLNWAYFIYCADMNTEEPKEYLTLRELNYARTSKYVSTDVSSCIYEEEMEFNQKCP---------TCKINENLWSITYYNKIRINLSDLSIDVMDDRFSATNGQSFIPFGTAKDCAGSTSCPKGHFKINLRGTGFSVSMETRWNEVYPKYGYRILRKQTSQIVKGWCGGHCSGCSPLKKFFVE 4779
            C   CG G       C+     D+N S+    +E+ C  +    RP+ +  C V  C    W    W  C + CG     R  +C +       +  C++   +P+  + C S + C   T                               +W T PW  CS++C    Q+R+V C          DE     ++ +          KP  +R C    C  W     G+C+  CG G R +   C++   +    ++        + L KP D R +C    C  ++ W    WS CSVSCG G + R++ C  ++ +        ++ CK+   P   + C+   CPKW    WS+C  +C  G Q R V C    + +I  +++C+   +  + + C   +   + W   +W +C+ +CG G + R + C   N ++        S  P +   C ++PC     W   + SEC    C  G     V C        N ++       C   + PS +   L        W   +W +     +SC + +  R V C+ +    Q   +C    KP+  + C +  NC  +P++CKE+K  +  S+DGEY L I       I+CA M+++ PKEY+TL   +    S+         +Y   +    +CP          C+ +      + + KIRI+L+ + I   D +F+ T+    +PF TA DC  +  CP+G F INL GTG S++   RW          I +      V G CGG+C  C+P     +E
Sbjct: 1194 CSATCGKGTRMRYVSCR-----DENGSV---ADESACATLP---RPVAKEECSVTPCG--QWKALDWSSCSVTCGQGRATRQVMCVNYSDHVIDRSECDQDY-IPETDQDC-SMSPCPQRTPDSGLAQHPFQNEDYRPRSASPSRTHVLGGNQWRTGPWGACSSTCAGGSQRRVVVC---------QDENGYTANDCVERI-------KPDEQRACESGPCPQWAYGNWGECTKLCGGGIRTRLVVCQRSNGERFPDLSC-------EILDKPPD-REQCNTHACPHDAAWSTGPWSSCSVSCGRGHKQRNVYCMAKDGSHL-----ESDYCKHLAKPHGHRKCRGGRCPKWKAGAWSQCSVSCGRGVQQRHVGCQIG-THKIARETECNPYTRPESERDCQGPRCPLYTWRAEEWQECTKTCGEGSRYRKVVCVDDNKNEVHGARCDVSKRPVDRESCSLQPC--EYVWITGEWSEC-SVTCGKGYKQRLVSCSEIYTGKENYEYSYQTTINCPGTQPPSVHPCYLRDCPVSATWRVGNWGSC---SVSCGVGVMQRSVQCLTN--EDQPSHLCHTDLKPEERKTCRNVYNC-ELPQNCKEVKRLKGASEDGEYFLMIRGK-LLKIFCAGMHSDHPKEYVTLVHGDSENFSE---------VYGHRLHNPTECPYNGSRRDDCQCRKDYTAAGFSSFQKIRIDLTSMQIITTDLQFARTSEGHPVPFATAGDCYSAAKCPQGRFSINLYGTGLSLTESARWISQGNYAVSDIKKSPDGTRVVGKCGGYCGKCTPSSGTGLE 1931

HSP 3 Score: 132.88 bits (333), Expect = 3.685e-30
Identity = 129/450 (28.67%), Postives = 188/450 (41.78%), Query Frame = 1 
Query: 2893 SPWSRCSNSCESELQKRMVYCFRSEKSDEILDEKFLKIHEQISDAFCD-IHSPKPITERPCSLNSCYFWIXXXXXXXXXXXXLGFRIQSHECKKKFNKNHEMITVDDKFCLKQNLVKPLDVRMRCFLKKCAIE---SFWIEMEWSKCSVSCGEGLQYRSLKCGYENENKTLTTWDNNEMCKNKMVPVSIQICKVTPCPKWIYSEWSECEGTCEYGSQHRTVLCTDPISEQILPDSKCDIKNKFPNFQKCLLSKLCGHWIVGKWSQCSASCGLGVKTRTITCNYSNGSKSIDHSVCKSVA-PFEEIHCQVKPC---------------STNAFWWLVKPSECYEYNCQPGIMYAHVRCVNRKFQVLYDSKCSRIKHPSYYVGCLNTTCRRYFWTAESWDNIPCPDISCTMKIRNRDVYCVDDYGNIQKDAMCDQSDKPDTWRLC---PSPQ 4173
             PW  CS  C+ E ++++V C R  +SD++           +SD  CD +  P  ITE PC  +    W  +   +CSA+CGLG+R     C K    + +   VDD FC      KP +       +KC+ E     W    W++CS SC  G Q R   C     N  L    ++  C ++   V+IQ C   PCP+W   +WSEC  TC  G +HR V C     E  L D  CD + K  + Q C   + C  W  G W QCS +CG G + R + C        +D + C +   P +   C++  C               +    W     + C    C  G    +V C +    V  +S C+ +  P     C  T C +  W A  W +     ++C      R V CV+   ++   + CDQ   P+T + C   P PQ
Sbjct:  885 GPWQACSKPCQGERKRKLV-CTR--ESDQLT----------VSDQRCDRLPQPGHITE-PCGTDCDLRWHVASRSECSAQCGLGYRTLDIYCAKYSRLDGKTEKVDDGFCSSH--PKPSN------REKCSGECNTGGWRYSAWTECSKSCDGGTQRRRAIC-VNTRNDVL----DDSKCTHQE-KVTIQRCSEFPCPQWKSGDWSECLVTCGKGHKHRQVWCQ--FGEDRLNDRMCDPETKPTSMQTCQQPE-CASWQAGPWGQCSVTCGQGYQLRAVKCIIGTYMSVVDDNDCNAATRPTDTQDCELPSCHPPPAAPETRRSTYSAPRTQWRFGSWTPC-SATCGKGTRMRYVSCRDENGSVADESACATLPRPVAKEECSVTPCGQ--WKALDWSSC---SVTCGQGRATRQVMCVNYSDHVIDRSECDQDYIPETDQDCSMSPCPQ 1297

HSP 4 Score: 126.331 bits (316), Expect = 2.995e-28
Identity = 114/415 (27.47%), Postives = 166/415 (40.00%), Query Frame = 1 
Query: 2518 SCPIRCGTGKVKIPFVCQKINNQDDNNSLWETVEENLCFAVDLVDR--PIEELNCVGQCNPLLWSYGKWEECPIECGTTFRYRNFICKDNKGLEWQKEWCERHLGLPDNKETCLSFNNCRNLTRWVTSPWSRCSNSCESELQKRMVYCFRSEKSDEILDEKFLKIHEQISDAFCDIHSPKPITERPCSLNSCYFWIXXXXXXXXXXXXLGFRIQSHECKKKFNKNHEMITVDDKFCLKQNLVKPL---DVRMRCFLKKCAIESFWIEMEWSKCSVSCGEGLQYRSLKCGYENENKTLTTWDNNEMCKNKMVPVSIQICKVTPCP-KWIYSEWSECEGTCEYGSQHRTVLCTDPIS--EQILPDSKCDIK---NKFPNFQKCLLSK--LCGHWIVGKWSQCSASCGLGVKTRTITC 3723
            +C   C  G  +   VCQ               +EN   A D V+R  P E+  C     P  W+YG W EC   CG   R R  +C+ + G  +    CE  L  P ++E C + + C +   W T PWS CS SC    ++R VYC   + S   L+  + K            H  KP   R C    C  W               +   S  C +   + H    +      ++    P    +    C   +C + + W   EW +C+ +CGEG +YR + C  +N+N+      +   C     PV  + C + PC   WI  EWSEC  TC  G + R V C++  +  E      +  I     + P+   C L    +   W VG W  CS SCG+GV  R++ C
Sbjct: 1339 ACSSTCAGGSQRRVVVCQ---------------DENGYTANDCVERIKPDEQRACESGPCPQ-WAYGNWGECTKLCGGGIRTRLVVCQRSNGERFPDLSCEI-LDKPPDREQC-NTHACPHDAAWSTGPWSSCSVSCGRGHKQRNVYCMAKDGSH--LESDYCK------------HLAKPHGHRKCRGGRCPKW-----------KAGAWSQCSVSCGRGVQQRHVGCQIGTHKIARETECNPYTRPESERDCQGPRCPLYT-WRAEEWQECTKTCGEGSRYRKVVCVDDNKNEV-----HGARCDVSKRPVDRESCSLQPCEYVWITGEWSECSVTCGKGYKQRLVSCSEIYTGKENYEYSYQTTINCPGTQPPSVHPCYLRDCPVSATWRVGNWGSCSVSCGVGVMQRSVQC 1704
[Close]
BLAST of A disintegrin and metalloproteinase with thrombospondin motifs vs. Ensembl Human
Match: ADAMTS20 (ADAM metallopeptidase with thrombospondin type 1 motif 20 [Source:HGNC Symbol;Acc:HGNC:17178])

HSP 1 Score: 347.821 bits (891), Expect = 3.805e-97
Identity = 360/1368 (26.32%), Postives = 547/1368 (39.99%), Query Frame = 1 
Query:  271 GVFQWDNKLWFIKPNTKTKFNSKFLKTEMNFLPHKIYFTALN--LNKPLFSCKL---------LKNNGYRNIPQESHF--SRVFQRMKRETYPVVDSE--------IVEPNIIELLIVVTSNFVKRFKKDFRQYILSNVAIATKLLHDPTIKASITXXXXXXXXXXEDYERNNDLHDWSLLSQDRVVSRFCHWVRQKKQLWNYS---WDSAILINDGVFSS-----NAIGIAHLRSMCND-NNCLAVVDRGFGTGFIIAHELAHQMNARHDFDNAEACSFFEKQYDNKTKYNTIMSTSLFFEYYPFIWSVCSQNVINSFLKSKYSFCLKQRNRHRNLYPHEQINEFFQKYSTGVDYDLNEQCSFAFGEKSEFCETDQNSRKKCSVLYCRL--KRYPICLRADAIIADGTECDVNQHCINGKCLYKNITIAPIDGGWSEYSEWSNCSRPCNGGVQFSYRTCDNPVPADGGRFCTGTKERIRSCNIEECSSFS-DPREESCGKYNLKPY----IPTNDEEFP----------CNLVC--ITTNHSLKYDISLTDGTPCSPFRSDICVKGTCYKTGCDRIVGSKKAIDNCNICAGQNDTCFKKESFFDGSKVAKVRMIRAFRIPPNVYNLFIKKVSQRMTPFTDEVY---DDFELLLVVNRRTVIRRSETIEPLAGGQ--LRYSGSKNKVETISIKGKLNVGISI-VIKVENTKTTLNLPFISYHYFV-----KDIFVWKYLEVITHPCKDQCGGFIEISPACFKKRDNQRYVDHYCSKATKPEPKIIKCGAICGYRWQRATEHYINSTVNKSCPIRCGTGKVKIPFVCQKINNQDDNNSLWETVEENLCFAVDLVDRPIEELNCVGQCNPLLWSYGKWEECPIECGTTFRYRNFICKDNKGLEWQKEWCERHLGLPDNKETCLSFNNCRNLTRWVTSPWSRCSNSCESELQKRMVYCFRSEKSDEILDEKFLKIHEQISDAFCDIHSPKPITERPCSLNSCYFWIXXXXXXXXXXXXLGFRIQSHECKKKFNKNHEMITVDDKFCLKQNLVKPLDVRMRCFLKKCAIES----------------FWIEMEWSKCSVSCGEGLQYRSLKCGYENENKTLTTWDNNEMCKNKMVPVSIQICKVTPCPKWIYSEWSECEGTCEYGSQHRTVLCTD---PISE-------QILPDSKCDIK------NKFP----------------------NFQKCLLSKLCG-HWIVGKWSQCSASCGLGVKTRTITCNYSNGSKSIDHSVCKSVA-PFEEIHCQVKPCSTNAFWWLVKPSECYEYNCQPGIMYAHVRCVNRKFQVLYDSKCSRIKHPSYYVGCLNTTC-RRYFWTAESW 4023
            G F+  N  +F++P  K   N      + +  PH IY   LN    + L  C +         L  + Y N+ ++ +    RV     +   P+ D          I  P  IE+++   +  V     + + YIL+ ++I   +  DP+I   I I VV +V++  + E      D +       +  FC W + +  L +      D+A+LI      S     N +G+++L ++C+   +C    ++G  + F IAHEL H +  +HD DN              TKY+ +M+ +L F   P+ WS CS+  +  FL + Y  CL  +       P E+I     +   G  YD N+QC  AFG  S+ C         C  L+C    K +  C       ADGT+C    HC +G C+ K     P++G W  +  +S+CSR C GG++ + R C+ P P +GG +C G + + RSCN + C   + D RE+ C  +N K      IP+N    P          C L C    TN+       + DGTPC     +I         GCD ++ S   ID C +C G N +C      F+ S      ++   +IP    N+ I++ S    P  D+ Y    D E   + N   ++  S+    + G +  + YSGS N VE I+   +    I I V+ V N    L  P + Y + +      D+F W         C   C G    +  C  K D+    D  C     P      C   C  RW     H I  +    C  +CG G   +   C K +  +      +TV+ +  +  D +  P +EL C G C    W Y +W +C   CG   R R   C +N G       C+    +   +E C  F    +   W  S WS C  +C    ++R V+C              L + + +SD FC+  S KP +  PC L++C  W     G C+  CG G++++  +C  +         ++D  C + +  +P D R  C L  C+  S                 W    W+ CSVSCG G Q R + C        L    +   C +   P  I  C  TPC +W   +WS C  +C +G   R VLC +   PI E       + L + +C +       + FP                      N  + +   + G  W  G W QCS+SC  G++ R + C   NG  +   S C + + P E   C   PC     W      EC +  C  GI    V C     Q+L D  C  +  P   + C    C     W  E W
Sbjct:  153 GTFKGQNGEYFLEPIMKADGNEY---EDGHNKPHLIYRQDLNNSFLQTLKYCSVSESQIKETSLPFHTYSNMNEDLNVMKERVLGHTSKNV-PLKDERRHSRKKRLISYPRYIEIMVTADAKVVSAHGSNLQNYILTLMSIVATIYKDPSIGNLIHIVVVKLVMIHREEEGPVINFDGAT-----TLKNFCSWQQTQNDLDDVHPSHHDTAVLITRYDICSSKEKCNMLGLSYLGTICDPLQSCFINEEKGLISAFTIAHELGHTLGVQHD-DNPRCKEM------KVTKYH-VMAPALSFHMSPWSWSNCSRKYVTEFLDTGYGECLLDK-------PDEEIYNLPSELP-GSRYDGNKQCELAFGPGSQMCP----HINICMHLWCTSTEKLHKGCFTQHVPPADGTDCGPGMHCRHGLCVNKETETRPVNGEWGPWEPYSSCSRTCGGGIESATRRCNRPEPRNGGNYCVGRRMKFRSCNTDSCPKGTQDFREKQCSDFNGKHLDISGIPSNVRWLPRYSGIGTKDRCKLYCQVAGTNYFYLLKDMVEDGTPCGTHSYNIDCNCVLKAAGCDHVLNSSAKIDKCGVCGGDNSSCKTITGVFNSSHYGYNVVV---KIPAGATNVDIRQYSYSGQP--DDSYLALSDAEGNFLFNGNFLLSTSKKEINVQGTRTVIEYSGSNNAVERINSTNRQEKEILIEVLCVGN----LYNPDVHYSFNIPLEERSDMFTWDPYGPW-EGCTKMCQGLQRRNITCIHKSDHSVVSDKECDHLPLPSFVTQSCNTDCELRW-----HVIGKS---ECSSQCGQGYRTLDIHCMKYSIHEG-----QTVQVDDHYCGDQLKPPTQEL-CHGNCVFTRWHYSEWSQCSRSCGGGERSRESYCMNNFGHRLADNECQELSRV--TRENCNEF----SCPSWAASEWSECLVTCGKGTKQRQVWC-------------QLNV-DHLSDGFCN-SSTKPESLSPCELHTCASWQVGPWGPCTTTCGHGYQMRDVKCVNELAS----AVLEDTECHEAS--RPSD-RQSCVLTPCSFISKLETALLPTVLIKKMAQWRHGSWTPCSVSCGRGTQARYVSC-----RDALDRIADESYCAHLPRPAEIWDC-FTPCGEWQAGDWSPCSASCGHGKTTRQVLCMNYHQPIDENYCDPEVRPLMEQECSLAACPPAHSHFPSSPVQPSYYLSTNLPLTQKLEDNENQVVHPSVRGNQWRTGPWGQCSSSCSGGLQHRAVVCQDENGQSA---SYCDAASKPPELQQCGPGPCPQ---WNYGNWGECSQ-TCGGGIKSRLVICQFPNGQILEDHNCEIVNKPPSVIQCHMHACPADVSWHQEPW 1426

HSP 2 Score: 115.161 bits (287), Expect = 7.297e-25
Identity = 135/521 (25.91%), Postives = 197/521 (37.81%), Query Frame = 1 
Query: 2695 LLWSYGKWEECPIECGTTFRYRNFIC-----KDNKGLEWQKEWCERHLGLPDNKETCLSFNNCRNLTRWVTSPWSRCSNSCESELQKRMVYCFRSEKSDEILDEKFLKIHEQISDAFCDIHSPKPITERPCSLNSCYFWIXXXXXXXXXXXXLGFRIQSHECKKKFNKNHEMITVDDKFCLKQNLVKPLDVRMRCFLKKCAIESFWIEMEWSKCSVSCGEGLQYRSLKCGYENENKTLTTWDNNEMCKNKMVPVSIQICKVTPC-------------------PKWIYSEWSECEGTCEYGSQHRTVLCTDPISEQILPDSKCDIKNKFPNFQKCLLSKLCGHWIVGKWSQCSASCGLGVKTRTITCNYSNGSKSIDHSVCK-SVAPFEEIHCQVKPCSTNAFWWLVKPSECYEYNCQPGIMYAHVRCVNRKFQVLYDSKCSRIKHPSYYVGCLNTTCRRYFWTAESWDNIPCPDISCTMKIRNRDVYCVDDYGNIQKDAMCDQSDKPDTWRLC---PSPQ 4173
            L W      EC  +CG  +R  +  C      + + ++    +C   L  P  +   L   NC   TRW  S WS+CS SC    + R  YC  +                +++D  C   S   +T   C+  SC  W  S+  +C   CG G + +   C+   N +H    + D FC   +  KP  +   C L  CA    W    W  C+ +CG G Q R +KC  E  +  L     +  C     P   Q C +TPC                    +W +  W+ C  +C  G+Q R V C D + ++I  +S C    +      C     CG W  G WS CSASCG G  TR + C   N  + ID + C   V P  E  C +  C          P     +   P +  ++    N       +   +++ HPS          R   W    W        SC+  +++R V C D+ G  Q  + CD + KP   + C   P PQ
Sbjct:  906 LRWHVIGKSECSSQCGQGYRTLDIHCMKYSIHEGQTVQVDDHYCGDQLKPPTQE---LCHGNCV-FTRWHYSEWSQCSRSCGGGERSRESYCMNN-------------FGHRLADNECQELSR--VTRENCNEFSCPSWAASEWSECLVTCGKGTKQRQVWCQ--LNVDH----LSDGFC--NSSTKPESLS-PCELHTCA---SWQVGPWGPCTTTCGHGYQMRDVKCVNELASAVL----EDTECHEASRPSDRQSCVLTPCSFISKLETALLPTVLIKKMAQWRHGSWTPCSVSCGRGTQARYVSCRDAL-DRIADESYCAHLPRPAEIWDCFTP--CGEWQAGDWSPCSASCGHGKTTRQVLC--MNYHQPIDENYCDPEVRPLMEQECSLAAC----------PPAHSHFPSSP-VQPSYYLSTNLPLTQKLEDNENQVVHPSV---------RGNQWRTGPWGQC---SSSCSGGLQHRAVVCQDENG--QSASYCDAASKPPELQQCGPGPCPQ 1361
[Close]
BLAST of A disintegrin and metalloproteinase with thrombospondin motifs vs. Ensembl Human
Match: ADAMTS20 (ADAM metallopeptidase with thrombospondin type 1 motif 20 [Source:HGNC Symbol;Acc:HGNC:17178])

HSP 1 Score: 345.51 bits (885), Expect = 1.799e-96
Identity = 361/1367 (26.41%), Postives = 553/1367 (40.45%), Query Frame = 1 
Query:  271 GVFQWDNKLWFIKPNTKTKFNSKFLKTEMNFLPHKIYFTALN--LNKPLFSCKL---------LKNNGYRNIPQESHF--SRVFQRMKRETYPVVDSE--------IVEPNIIELLIVVTSNFVKRFKKDFRQYILSNVAIATKLLHDPTIKASITXXXXXXXXXXEDYERNNDLHDWSLLSQDRVVSRFCHWVRQKKQLWNYS---WDSAILIN-DGVFSS----NAIGIAHLRSMCND-NNCLAVVDRGFGTGFIIAHELAHQMNARHDFDNAEACSFFEKQYDNKTKYNTIMSTSLFFEYYPFIWSVCSQNVINSFLKSKYSFCLKQRNRHRNLYPHEQINEFFQKYSTGVDYDLNEQCSFAFGEKSEFCETDQNSRKKCSVLYCRL--KRYPICLRADAIIADGTECDVNQHCINGKCLYKNITIAPIDGGWSEYSEWSNCSRPCNGGVQFSYRTCDNPVPADGGRFCTGTKERIRSCNIEECSSFS-DPREESCGKYNLKPY----IPTNDEEFP----------CNLVC--ITTNHSLKYDISLTDGTPCSPFRSDICVKGTCYKTGCDRIVGSKKAIDNCNICAGQNDTCFKKESFFDGSKVAKVRMIRAFRIPPNVYNLFIKKVSQRMTPFTDEVY---DDFELLLVVNRRTVIRRSETIEPLAGGQ--LRYSGSKNKVETISIKGKLNVGISIVIKVENTKTTLNLPFISYHYFV-----KDIFVWKYLEVITHPCKDQCGGFIEISPACFKKRDNQRYVDHYCSKATKPEPKIIKCGAICGYRWQRATEHYINSTVNKSCPIRCGTGKVKIPFVCQKINNQDDNNSLWETVEENLCFAVDLVDRPIEELNCVGQCNPLLWSYGKWEECPIECGTTFRYRNFICKDNKGLEWQKEWCERHLGLPDNKETCLSFNNCRNLTRWVTSPWSRCSNSCESELQKRMVYCFRSEKSDEILDEKFLKIHEQISDAFCDIHSPKPITERPCSLNSCYFWIXXXXXXXXXXXXLGFRIQSHECKKKFNKNHEMITVDDKFCLKQNLVKPLDVRMRCFLKKCAIES----------------FWIEMEWSKCSVSCGEGLQYRSLKCGYENENKTLTTWDNNEMCKNKMVPVSIQICKVTPCPKWIYSEWSECEGTCEYGSQHRTVLCTD---PISE-------QILPDSKCDIK------NKFP----------------------NFQKCLLSKLCG-HWIVGKWSQCSASCGLGVKTRTITCNYSNGSKSIDHSVCKSVA-PFEEIHCQVKPCSTNAFWWLVKPSECYEYNCQPGIMYAHVRCVNRKFQVLYDSKCSRIKHPSYYVGCLNTTC-RRYFWTAESW 4023
            G F+  N  +F++P  K   N      + +  PH IY   LN    + L  C +         L  + Y N+ ++ +    RV     +   P+ D          I  P  IE+++   +  V     + + YIL+ ++I   +  DP+I   I I VV +V++  + E      D +       +  FC W + +  L +      D+A+LI  + + SS    N +G+++L ++C+   +C    ++G  + F IAHEL H +  +HD DN              TKY+ +M+ +L F   P+ WS CS+  +  FL + Y  CL  +       P E+I     +   G  YD N+QC  AFG  S+ C         C  L+C    K +  C       ADGT+C    HC +G C+ K     P++G W  +  +S+CSR C GG++ + R C+ P P +GG +C G + + RSCN + C   + D RE+ C  +N K      IP+N    P          C L C    TN+       + DGTPC     DICV+G C   GCD ++ S   ID C +C G N +C      F+ S      ++   +IP    N+ I++ S    P  D+ Y    D E   + N   ++  S+    + G +  + YSGS N VE I+   +      ++++V       N P + Y + +      D+F W         C   C G    +  C  K D+    D  C     P      C   C  RW     H I  +    C  +CG G   +   C K +  +      +TV+ +  +  D +  P +EL C G C    W Y +W +C   CG   R R   C +N G       C+    +   +E C  F    +   W  S WS C  +C    ++R V+C              L + + +SD FC+  S KP +  PC L++C  W     G C+  CG G++++  +C  +         ++D  C + +  +P D R  C L  C+  S                 W    W+ CSVSCG G Q R + C        L    +   C +   P  I  C  TPC +W   +WS C  +C +G   R VLC +   PI E       + L + +C +       + FP                      N  + +   + G  W  G W  CS+SC  G++ R + C   NG  +   S C + + P E   C   PC     W      EC +  C  GI    V C     Q+L D  C  +  P   + C    C     W  E W
Sbjct:  153 GTFKGQNGEYFLEPIMKADGNEY---EDGHNKPHLIYRQDLNNSFLQTLKYCSVSESQIKETSLPFHTYSNMNEDLNVMKERVLGHTSKNV-PLKDERRHSRKKRLISYPRYIEIMVTADAKVVSAHGSNLQNYILTLMSIVATIYKDPSIGNLIHIVVVKLVMIHREEEGPVINFDGAT-----TLKNFCSWQQTQNDLDDVHPSHHDTAVLITREDICSSKEKCNMLGLSYLGTICDPLQSCFINEEKGLISAFTIAHELGHTLGVQHD-DNPRCKEM------KVTKYH-VMAPALSFHMSPWSWSNCSRKYVTEFLDTGYGECLLDK-------PDEEIYNLPSELP-GSRYDGNKQCELAFGPGSQMCP----HINICMHLWCTSTEKLHKGCFTQHVPPADGTDCGPGMHCRHGLCVNKETETRPVNGEWGPWEPYSSCSRTCGGGIESATRRCNRPEPRNGGNYCVGRRMKFRSCNTDSCPKGTQDFREKQCSDFNGKHLDISGIPSNVRWLPRYSGIGTKDRCKLYCQVAGTNYFYLLKDMVEDGTPCGTETHDICVQGQCMAAGCDHVLNSSAKIDKCGVCGGDNSSCKTITGVFNSSHYGYNVVV---KIPAGATNVDIRQYSYSGQP--DDSYLALSDAEGNFLFNGNFLLSTSKKEINVQGTRTVIEYSGSNNAVERINSTNRQEK--ELILQVLCVGNLYN-PDVHYSFNIPLEERSDMFTWDPYGPW-EGCTKMCQGLQRRNITCIHKSDHSVVSDKECDHLPLPSFVTQSCNTDCELRW-----HVIGKS---ECSSQCGQGYRTLDIHCMKYSIHEG-----QTVQVDDHYCGDQLKPPTQEL-CHGNCVFTRWHYSEWSQCSRSCGGGERSRESYCMNNFGHRLADNECQELSRV--TRENCNEF----SCPSWAASEWSECLVTCGKGTKQRQVWC-------------QLNV-DHLSDGFCN-SSTKPESLSPCELHTCASWQVGPWGPCTTTCGHGYQMRDVKCVNELAS----AVLEDTECHEAS--RPSD-RQSCVLTPCSFISKLETALLPTVLIKKMAQWRHGSWTPCSVSCGRGTQARYVSC-----RDALDRIADESYCAHLPRPAEIWDC-FTPCGEWQAGDWSPCSASCGHGKTTRQVLCMNYHQPIDENYCDPEVRPLMEQECSLAACPPAHSHFPSSPVQPSYYLSTNLPLTQKLEDNENQVVHPSVRGNQWRTGPWGSCSSSCSGGLQHRAVVCQDENGQSA---SYCDAASKPPELQQCGPGPCPQ---WNYGNWGECSQ-TCGGGIKSRLVICQFPNGQILEDHNCEIVNKPPSVIQCHMHACPADVSWHQEPW 1426

HSP 2 Score: 108.997 bits (271), Expect = 5.344e-23
Identity = 135/521 (25.91%), Postives = 198/521 (38.00%), Query Frame = 1 
Query: 2695 LLWSYGKWEECPIECGTTFRYRNFIC-----KDNKGLEWQKEWCERHLGLPDNKETCLSFNNCRNLTRWVTSPWSRCSNSCESELQKRMVYCFRSEKSDEILDEKFLKIHEQISDAFCDIHSPKPITERPCSLNSCYFWIXXXXXXXXXXXXLGFRIQSHECKKKFNKNHEMITVDDKFCLKQNLVKPLDVRMRCFLKKCAIESFWIEMEWSKCSVSCGEGLQYRSLKCGYENENKTLTTWDNNEMCKNKMVPVSIQICKVTPC-------------------PKWIYSEWSECEGTCEYGSQHRTVLCTDPISEQILPDSKCDIKNKFPNFQKCLLSKLCGHWIVGKWSQCSASCGLGVKTRTITCNYSNGSKSIDHSVCK-SVAPFEEIHCQVKPCSTNAFWWLVKPSECYEYNCQPGIMYAHVRCVNRKFQVLYDSKCSRIKHPSYYVGCLNTTCRRYFWTAESWDNIPCPDISCTMKIRNRDVYCVDDYGNIQKDAMCDQSDKPDTWRLC---PSPQ 4173
            L W      EC  +CG  +R  +  C      + + ++    +C   L  P  +   L   NC   TRW  S WS+CS SC    + R  YC  +                +++D  C   S   +T   C+  SC  W  S+  +C   CG G + +   C+   N +H    + D FC   +  KP  +   C L  CA    W    W  C+ +CG G Q R +KC  E  +  L     +  C     P   Q C +TPC                    +W +  W+ C  +C  G+Q R V C D + ++I  +S C    +      C     CG W  G WS CSASCG G  TR + C   N  + ID + C   V P  E  C +  C          P     +   P +  ++    N       +   +++ HPS          R   W    W +      SC+  +++R V C D+ G  Q  + CD + KP   + C   P PQ
Sbjct:  906 LRWHVIGKSECSSQCGQGYRTLDIHCMKYSIHEGQTVQVDDHYCGDQLKPPTQE---LCHGNCV-FTRWHYSEWSQCSRSCGGGERSRESYCMNN-------------FGHRLADNECQELSR--VTRENCNEFSCPSWAASEWSECLVTCGKGTKQRQVWCQ--LNVDH----LSDGFC--NSSTKPESLS-PCELHTCA---SWQVGPWGPCTTTCGHGYQMRDVKCVNELASAVL----EDTECHEASRPSDRQSCVLTPCSFISKLETALLPTVLIKKMAQWRHGSWTPCSVSCGRGTQARYVSCRDAL-DRIADESYCAHLPRPAEIWDCFTP--CGEWQAGDWSPCSASCGHGKTTRQVLC--MNYHQPIDENYCDPEVRPLMEQECSLAAC----------PPAHSHFPSSP-VQPSYYLSTNLPLTQKLEDNENQVVHPSV---------RGNQWRTGPWGSC---SSSCSGGLQHRAVVCQDENG--QSASYCDAASKPPELQQCGPGPCPQ 1361
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BLAST of A disintegrin and metalloproteinase with thrombospondin motifs vs. Ensembl Human
Match: ADAMTS9 (ADAM metallopeptidase with thrombospondin type 1 motif 9 [Source:HGNC Symbol;Acc:HGNC:13202])

HSP 1 Score: 346.665 bits (888), Expect = 4.717e-96
Identity = 327/1331 (24.57%), Postives = 515/1331 (38.69%), Query Frame = 1 
Query:  436 NGYRNIPQESHFSRVFQRMKRETYPVVDSEIVEPNIIELLIVVTSNFVKRFKKDFRQYILSNVAIATKLLHDPTIKASITXXXXXXXXXXEDYERNNDLHDWSLLSQDRVVSRFCHWVRQKKQLWNYSWDSAILINDGVF-----SSNAIGIAHLRSMCND-NNCLAVVDRGFGTGFIIAHELAHQMNARHDFDNAEACSFFEKQYDNKTKYNTIMSTSLFFEYYPFIWSVCSQNVINSFLKSKYSFCLKQRNRHRNLYPHEQINEFFQKYSTGVDYDLNEQCSFAFGEKSEFCETDQNSRKKCSVLYCRLKR--YPICLRADAIIADGTECDVNQHCINGKCLYKNITIAPIDGGWSEYSEWSNCSRPCNGGVQFSYRTCDNPVPADGGRFCTGTKERIRSCNIEEC-SSFSDPREESCGKYNLKPY----IPTNDEEFP----------CNLVCITTNHSLKYDI--SLTDGTPCSPFRSDICVKGTCYKTGCDRIVGSKKAIDNCNICAGQNDTCFKKESFFDGSKVAKVRMIRAFRIPPNVYNLFIKKVSQRMTPFTDEVYDDFELLLVVNRRTVIRRSETIEPLAGGQLR-------YSGSKNKVETIS----IKGKLNVGISIVIKVEN--TKTTLNLPF--ISYHYFVKDIFVWKYLEVITHPCKDQCGGFIEISPACFKKRDNQRYVDHYCSKATKPEPKIIKCGAICGYRWQRATEHYINSTVNKSCPIRCGTGKVKIPFVCQKINNQDDNNSLWETVEENLCFAVDLVDRPIEELNCVGQCNPLLWSYGKWEECPIECGTTFRYRNFICKDNKGLEWQKEWCERHLGLPDNKETCLSFNNCRNLTRWVTSPWSRCSNSCESELQKRMVYCFRSEKSDEILDEKFLKIHEQISDAFCDIHSPKPITERPCSLNSCYFWIXXXXXXXXXXXXLGFRIQSHECKKKFNKNHEMITVDDKFCLKQNLVKPLDVRMRCFLKKC---------------AIESFWIEMEWSKCSVSCGEGLQYRSLKCGYENENKTLTTWDNNEMCKNKMVPVSIQICKVTPCPKWIYSEWSECEGTCEYGSQHRTVLCTDPISEQILPDSKCDIKNKFPNFQKCLL---------SKLCGH------------------------WIVGKWSQCSASCGLGVKTRTITCNYSNGSKSIDHSVCKSVAPFEEIHCQVKPCSTNAFWWLVKPSECYEYNCQPGIMYAHVRCVNRKFQVLYDSKCSRIKHPSYYVGCLNTTC-RRYFWTAESWDNIPCPDISCTMKIRNRDVYCVDDYGNIQKDAMCDQSDKPDTWRLC 4161
            + Y N    +   R  +R KR         +  P  +E+L+V  +  V    ++ + YIL+ ++I       P+I                              +    +  FC W   K        D+A+L+            + +G+A L ++C+   +C    D G  T F IAHEL H  N  HD +N       + + +       +M+ +L F   P++WS CS+  I  FL + Y  CL      R  YP             G+ Y++N+QC   FG  S+ C        +C  L+C      +  C       ADGTEC+  +HC  G C+ K + +   DG W  +S +  CSR C GG++ + R C+ P P +GG++C G + + +SCN E C     D R+E C  ++ K +    +  N    P          C L C    ++  Y +   + DGTPC    +DICV+G C + GCD ++ SK   D C +C G N +C      F+        ++   RIP    N+ +++ S     F+ E  DD  L L  ++   +     +  +A  ++R       YSGS+  VE I+    I+ +L + +  V K+ N   + + N+P       ++      W+        C   C G  +    C ++ D     D  C +  +P      CG  C  RW  A+           C  +CG G   +   C K +  D      E V++  C +     +P     C G+CN   W Y  W EC   C    + R  IC + +        C     +    + C  F       +W +  WS C  +C    + R V+C   E              ++++D  CD  + KP + + C    C  W     G+CS  CG G+++++ +C         M  VDD  C      +P D +  C L  C               A  + W    W+ CS +CG+G + R + C   +EN ++    +   C     PV+ + C VTPC +W   +WS C  TC  G   R V+C +  S+ ++  S+CD        Q C +         S L  H                        W  G W  CS++C  G + R + C   NG  + D    + + P E+  C+  PC     W      EC +  C  GI    V C     +   D  C  +  P     C    C     W+   W +     +SC    + R+VYC+   G+  +   C    KP   R C
Sbjct:  267 SAYGNKTDNTREKRTHRRTKRF--------LSYPRFVEVLVVADNRMVSYHGENLQHYILTLMSI-----DGPSIS----------------------------FNAQTTLKNFCQWQHSKNSPGGIHHDTAVLLTRQDICRAHDKCDTLGLAELGTICDPYRSCSISEDSGLSTAFTIAHELGHVFNMPHDDNN-------KCKEEGVKSPQHVMAPTLNFYTNPWMWSKCSRKYITEFLDTGYGECLLNEPESRP-YP-------LPVQLPGILYNVNKQCELIFGPGSQVCPY----MMQCRRLWCNNVNGVHKGCRTQHTPWADGTECEPGKHCKYGFCVPKEMDVPVTDGSWGSWSPFGTCSRTCGGGIKTAIRECNRPEPKNGGKYCVGRRMKFKSCNTEPCLKQKRDFRDEQCAHFDGKHFNINGLLPNVRWVPKYSGILMKDRCKLFCRVAGNTAYYQLRDRVIDGTPCGQDTNDICVQGLCRQAGCDHVLNSKARRDKCGVCGGDNSSCKTVAGTFNTVHYGYNTVV---RIPAGATNIDVRQHS-----FSGETDDDNYLALSSSKGEFLLNGNFVVTMAKREIRIGNAVVEYSGSETAVERINSTDRIEQELLLQVLSVGKLYNPDVRYSFNIPIEDKPQQFYWNSHGPWQ-------ACSKPCQGERKRKLVCTRESDQLTVSDQRCDRLPQPGHITEPCGTDCDLRWHVASR--------SECSAQCGLGYRTLDIYCAKYSRLDGKT---EKVDDGFCSS---HPKPSNREKCSGECNTGGWRYSAWTECSKSCDGGTQRRRAICVNTRNDVLDDSKCTHQEKV--TIQRCSEF----PCPQWKSGDWSECLVTCGKGHKHRQVWCQFGE--------------DRLNDRMCDPET-KPTSMQTCQQPECASWQAGPWGQCSVTCGQGYQLRAVKCI----IGTYMSVVDDNDC--NAATRPTDTQ-DCELPSCHPPPAAPETRRSTYSAPRTQWRFGSWTPCSATCGKGTRMRYVSC--RDENGSVA---DESACATLPRPVAKEECSVTPCGQWKALDWSSCSVTCGQGRATRQVMCVN-YSDHVIDRSECDQDYIPETDQDCSMSPCPQRTPDSGLAQHPFQNEDYRPRSASPSRTHVLGGNQWRTGPWGACSSTCAGGSQRRVVVCQDENGYTAND--CVERIKPDEQRACESGPCPQ---WAYGNWGECTKL-CGGGIRTRLVVCQRSNGERFPDLSCEILDKPPDREQCNTHACPHDAAWSTGPWSSC---SVSCGRGHKQRNVYCMAKDGSHLESDYCKHLAKPHGHRKC 1465

HSP 2 Score: 206.068 bits (523), Expect = 1.620e-52
Identity = 199/802 (24.81%), Postives = 328/802 (40.90%), Query Frame = 1 
Query: 2521 CPIRCGTGKVKIPFVCQKINNQDDNNSLWETVEENLCFAVDLVDRPIEELNC-VGQCNPLLWSYGKWEECPIECGTTFRYRNFICKDNKGLEWQKEWCERHLGLPDNKETCLSFNNCRNLT-------------------------------RWVTSPWSRCSNSCESELQKRMVYCFRSEKSDEILDEKFLKIHEQISDAFCDIHSPKPITERPCSLNSCYFWIXXXXXXXXXXXXLGFRIQSHECKKKFNKNHEMITVDDKFCLKQNLVKPLDVRMRCFLKKCAIESFWIEMEWSKCSVSCGEGLQYRSLKCGYENENKTLTTWDNNEMCKNKMVPVSIQICKVTPCPKWIYSEWSECEGTCEYGSQHRTVLCTDPISEQILPDSKCDIKNKFPNFQKCLLSKLCGH-WIVGKWSQCSASCGLGVKTRTITCNYSNGSKSIDHSVCKSVAPFEEIHCQVKPCSTNAFWWLVKPSECYEYNCQPGIMYAHVRCV-------NRKFQVLYDSKCSRIKHPSYYVGCLNTTCRRYFWTAESWDNIPCPDISCTMKIRNRDVYCVDDYGNIQKDAMCDQSDKPDTWRLCPSPQNCSNIPRSCKELKSRQSVSKDGEYSLAIDLNWAYFIYCADMNTEEPKEYLTLRELNYARTSKYVSTDVSSCIYEEEMEFNQKCP---------TCKINENLWSITYYNKIRINLSDLSIDVMDDRFSATNGQSFIPFGTAKDCAGSTSCPKGHFKINLRGTGFSVSMETRWNEVYPKYGYRILRKQTSQIVKGWCGGHCSGCSPLKKFFVE 4779
            C   CG G  ++ +V    + +D+N S+    +E+ C  +    RP+ +  C V  C    W    W  C + CG     R  +C +       +  C++   +P+  + C S + C   T                               +W T PW  CS++C    Q+R+V C          DE     ++ +          KP  +R C    C  W     G+C+  CG G R +   C++   +    ++        + L KP D R +C    C  ++ W    WS CSVSCG G + R++ C  ++ +        ++ CK+   P   + C+   CPKW    WS+C  +C  G Q R V C    + +I  +++C+   +  + + C   +   + W   +W +C+ +CG G + R + C   N ++        S  P +   C ++PC     W   + SEC    C  G     V C        N ++       C   + PS +   L        W   +W +     +SC + +  R V C+ +    Q   +C    KP+  + C +  NC  +P++CKE+K  +  S+DGEY L I       I+CA M+++ PKEY+TL   +    S+         +Y   +    +CP          C+ +      + + KIRI+L+ + I   D +F+ T+    +PF TA DC  +  CP+G F INL GTG S++   RW          I +      V G CGG+C  C+P     +E
Sbjct: 1166 CSATCGKG-TRMRYV----SCRDENGSV---ADESACATLP---RPVAKEECSVTPCG--QWKALDWSSCSVTCGQGRATRQVMCVNYSDHVIDRSECDQDY-IPETDQDC-SMSPCPQRTPDSGLAQHPFQNEDYRPRSASPSRTHVLGGNQWRTGPWGACSSTCAGGSQRRVVVC---------QDENGYTANDCVERI-------KPDEQRACESGPCPQWAYGNWGECTKLCGGGIRTRLVVCQRSNGERFPDLSC-------EILDKPPD-REQCNTHACPHDAAWSTGPWSSCSVSCGRGHKQRNVYCMAKDGSHL-----ESDYCKHLAKPHGHRKCRGGRCPKWKAGAWSQCSVSCGRGVQQRHVGC-QIGTHKIARETECNPYTRPESERDCQGPRCPLYTWRAEEWQECTKTCGEGSRYRKVVCVDDNKNEVHGARCDVSKRPVDRESCSLQPC--EYVWITGEWSEC-SVTCGKGYKQRLVSCSEIYTGKENYEYSYQTTINCPGTQPPSVHPCYLRDCPVSATWRVGNWGSC---SVSCGVGVMQRSVQCLTN--EDQPSHLCHTDLKPEERKTCRNVYNC-ELPQNCKEVKRLKGASEDGEYFLMIRGK-LLKIFCAGMHSDHPKEYVTLVHGDSENFSE---------VYGHRLHNPTECPYNGSRRDDCQCRKDYTAAGFSSFQKIRIDLTSMQIITTDLQFARTSEGHPVPFATAGDCYSAAKCPQGRFSINLYGTGLSLTESARWISQGNYAVSDIKKSPDGTRVVGKCGGYCGKCTPSSGTGLE 1903

HSP 3 Score: 132.494 bits (332), Expect = 4.837e-30
Identity = 129/450 (28.67%), Postives = 188/450 (41.78%), Query Frame = 1 
Query: 2893 SPWSRCSNSCESELQKRMVYCFRSEKSDEILDEKFLKIHEQISDAFCD-IHSPKPITERPCSLNSCYFWIXXXXXXXXXXXXLGFRIQSHECKKKFNKNHEMITVDDKFCLKQNLVKPLDVRMRCFLKKCAIE---SFWIEMEWSKCSVSCGEGLQYRSLKCGYENENKTLTTWDNNEMCKNKMVPVSIQICKVTPCPKWIYSEWSECEGTCEYGSQHRTVLCTDPISEQILPDSKCDIKNKFPNFQKCLLSKLCGHWIVGKWSQCSASCGLGVKTRTITCNYSNGSKSIDHSVCKSVA-PFEEIHCQVKPC---------------STNAFWWLVKPSECYEYNCQPGIMYAHVRCVNRKFQVLYDSKCSRIKHPSYYVGCLNTTCRRYFWTAESWDNIPCPDISCTMKIRNRDVYCVDDYGNIQKDAMCDQSDKPDTWRLC---PSPQ 4173
             PW  CS  C+ E ++++V C R  +SD++           +SD  CD +  P  ITE PC  +    W  +   +CSA+CGLG+R     C K    + +   VDD FC      KP +       +KC+ E     W    W++CS SC  G Q R   C     N  L    ++  C ++   V+IQ C   PCP+W   +WSEC  TC  G +HR V C     E  L D  CD + K  + Q C   + C  W  G W QCS +CG G + R + C        +D + C +   P +   C++  C               +    W     + C    C  G    +V C +    V  +S C+ +  P     C  T C +  W A  W +     ++C      R V CV+   ++   + CDQ   P+T + C   P PQ
Sbjct:  857 GPWQACSKPCQGERKRKLV-CTR--ESDQLT----------VSDQRCDRLPQPGHITE-PCGTDCDLRWHVASRSECSAQCGLGYRTLDIYCAKYSRLDGKTEKVDDGFCSSH--PKPSN------REKCSGECNTGGWRYSAWTECSKSCDGGTQRRRAIC-VNTRNDVL----DDSKCTHQE-KVTIQRCSEFPCPQWKSGDWSECLVTCGKGHKHRQVWCQ--FGEDRLNDRMCDPETKPTSMQTCQQPE-CASWQAGPWGQCSVTCGQGYQLRAVKCIIGTYMSVVDDNDCNAATRPTDTQDCELPSCHPPPAAPETRRSTYSAPRTQWRFGSWTPC-SATCGKGTRMRYVSCRDENGSVADESACATLPRPVAKEECSVTPCGQ--WKALDWSSC---SVTCGQGRATRQVMCVNYSDHVIDRSECDQDYIPETDQDCSMSPCPQ 1269

HSP 4 Score: 126.331 bits (316), Expect = 3.615e-28
Identity = 114/415 (27.47%), Postives = 166/415 (40.00%), Query Frame = 1 
Query: 2518 SCPIRCGTGKVKIPFVCQKINNQDDNNSLWETVEENLCFAVDLVDR--PIEELNCVGQCNPLLWSYGKWEECPIECGTTFRYRNFICKDNKGLEWQKEWCERHLGLPDNKETCLSFNNCRNLTRWVTSPWSRCSNSCESELQKRMVYCFRSEKSDEILDEKFLKIHEQISDAFCDIHSPKPITERPCSLNSCYFWIXXXXXXXXXXXXLGFRIQSHECKKKFNKNHEMITVDDKFCLKQNLVKPL---DVRMRCFLKKCAIESFWIEMEWSKCSVSCGEGLQYRSLKCGYENENKTLTTWDNNEMCKNKMVPVSIQICKVTPCP-KWIYSEWSECEGTCEYGSQHRTVLCTDPIS--EQILPDSKCDIK---NKFPNFQKCLLSK--LCGHWIVGKWSQCSASCGLGVKTRTITC 3723
            +C   C  G  +   VCQ               +EN   A D V+R  P E+  C     P  W+YG W EC   CG   R R  +C+ + G  +    CE  L  P ++E C + + C +   W T PWS CS SC    ++R VYC   + S   L+  + K            H  KP   R C    C  W               +   S  C +   + H    +      ++    P    +    C   +C + + W   EW +C+ +CGEG +YR + C  +N+N+      +   C     PV  + C + PC   WI  EWSEC  TC  G + R V C++  +  E      +  I     + P+   C L    +   W VG W  CS SCG+GV  R++ C
Sbjct: 1311 ACSSTCAGGSQRRVVVCQ---------------DENGYTANDCVERIKPDEQRACESGPCPQ-WAYGNWGECTKLCGGGIRTRLVVCQRSNGERFPDLSCEI-LDKPPDREQC-NTHACPHDAAWSTGPWSSCSVSCGRGHKQRNVYCMAKDGSH--LESDYCK------------HLAKPHGHRKCRGGRCPKW-----------KAGAWSQCSVSCGRGVQQRHVGCQIGTHKIARETECNPYTRPESERDCQGPRCPLYT-WRAEEWQECTKTCGEGSRYRKVVCVDDNKNEV-----HGARCDVSKRPVDRESCSLQPCEYVWITGEWSECSVTCGKGYKQRLVSCSEIYTGKENYEYSYQTTINCPGTQPPSVHPCYLRDCPVSATWRVGNWGSCSVSCGVGVMQRSVQC 1676
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BLAST of A disintegrin and metalloproteinase with thrombospondin motifs vs. Ensembl Celegans
Match: gon-1 (A disintegrin and metalloproteinase with thrombospondin motifs gon-1 [Source:UniProtKB/Swiss-Prot;Acc:Q19791])

HSP 1 Score: 328.561 bits (841), Expect = 1.166e-90
Identity = 336/1299 (25.87%), Postives = 516/1299 (39.72%), Query Frame = 1 
Query:  544 IELLIVVTSNFVKRFKKDFRQYILSNVAIATKLLHDPTIKASITXXXXXXXXXXEDYERNNDLHDWSLLSQDRVVSRFCHWVRQKKQLWNYSWDSAILINDGVF------------SSNAIGIAHLRSMCN-DNNCLAVVDRGFGTGFIIAHELAHQMNARHDFDNAEACSFFEKQYDNKTKYNTIMSTSLFFEYYPFIWSVCSQNVINSFLKSK--YSFCLKQRNRHRNLYPHEQINEFFQKYSTGVDYDLNEQCSFAFGEKSEFCETDQNSRKK-CSVLY-----CRLKRYPICLRADAIIADGTECDVNQH--CINGKCL-YKNITIAPIDGGWSEYSEWSNCSRPCNGGVQFSYRTCDNPVPADGGRFCTGTKERIRSCNIEECSSFSDP-REESCGKYN-----LKPYIPTNDEEFP----------CNLVCITTNHSLKYDI--SLTDGTPCSPFRSDICVKGTCYKTGCDRIVGSKKAIDNCNICAGQNDTCFKKESFFDGSKVAKVRMIRAFRIPPNVYNLFIKKVSQRMTPFTDEVYDDFELLLVVNRRTVIRRSETIEPLAGGQ-------LRYSGSKNKVETISIKGKLNVGISI-VIKVENTKTTLNLPFISYHYFVKDI------------FVWKYLEVITHPCKDQCGGFIEISPACFKKRDNQRYVDHYCSKATKPEPKIIKCGAICGYRWQRATEHYINSTVNKSCPIRCGTGKVKIPFVCQKINNQDDNNSLWETVEENLCFAVDLVDRPIEELNCVGQCNPLLWSYGKWEECPIECGTTFR-YRNFICKDNKGLEWQKEWCERHLGLPDNKETCLSFNNCRNLTRWVTSPWSRCSNSCESELQKRMVYCFRSEKSDEILDEKFLKIHEQISDAFCDIHSPKPITERPCSLNSCYFWIXXXXXXXXXXXXLGFRIQSHECKKKFNKNHEMITVDDKFCLKQN--LVKPLDVRMRCFLKKCAIESFWIEMEWSKCSVSCGEGLQYRSLKCGYENENKTLTTWDNNEMCKNKM-VPVSIQICKVTPCPKWIYSEWSECEGTCEYGSQHRTVLCTDPISEQILPDSKCDIKNKFPNFQKCLLSKLCGHWIVGKWSQCSASCGLGVKTRTITCNYSNGSKSIDHSVC-KSVAPFEEIHCQVKPC-----------STNAFWWLVKPSECYEYNCQPGIMYAHVRCVNRKFQVLYDSKCSRIKHPSYYVGCLNTTCRRYFWTAESWDNIPCPDISCTMKIRNRDVYCV---DDYGNIQKDAMCDQSDKPDTWRLC---PSPQNCSNI 4188
            +E+L+V  +   +   +    Y+L+  +    +    +++ASI + VV +++L  +        +     QD     FC W    +Q +N   DS++  +D                 + +G+A L +MC+   +C  + D G    F IAHEL H  +  HD  +   CS +     NK  ++ IM+ +L +  +P+ WS CS  ++  FL++    + CL  +   R  Y      + F +   G  YD ++QC F FG  SE C      R+  C+  Y     CR +  P         ADGT CD ++   C +G C+     ++  IDG W ++  W  CSR C GGVQ   R CD+P P +GG++C G +ER RSCN +EC   + P RE  C ++N     ++    TN    P          C L C  +  +  Y +   + DGTPC     DICV G C   GCD  + S    D C +C G + +C   +  F+         +   +IP    N+ I     R   + +   DD  L L       +        LA  Q       L YSGS   +E I+  G +   I + V+ V +     + P ISY Y    +            ++W+  +  T  C   C G       C     +++  D  C    KP+     C   C  RW       I   V+ SC  +CG+G+ +    C K+              E+LC   D   +P +  +C   C+   W+YG+W  C   CG+  + +R   C D+      +  C R     + KE      N     RWV   WS CS SC+  ++ R   C         LD    + H                T+  C+ ++C +W       CSAKCG G + +   C  +    H  +  + + CLK    + KP      C  + C         EWS+CSVSC +G   R + C   N  +      +  +C      P S Q C +  CP W  ++WS C  +C  G + RT  C     EQ +  S C         Q C L   C  W    WS CS +CG G++TR+++C   +    +D   C ++  P  +  C+   C                 W   P       C  G     ++C +   + L D  C+ +        C    C   +W    W+   CP    T   ++R+V CV   D    I KD  CD   +P + R C   P P+   +I
Sbjct:  282 VEVLVVADTKMYEYHGRSLEDYVLTLFSTVASIYRHQSLRASINVVVVKLIVLKTENAGPRITQNAQQTLQD-----FCRW----QQYYNDPDDSSVQHHDVAILLTRKDICRSQGKCDTLGLAELGTMCDMQKSCAIIEDNGLSAAFTIAHELGHVFSIPHD--DERKCSTYMPV--NKNNFH-IMAPTLEYNTHPWSWSPCSAGMLERFLENNRGQTQCLFDQPVERRYY-----EDVFVRDEPGKKYDAHQQCKFVFGPASELCPYMPTCRRLWCATFYGSQMGCRTQHMPW--------ADGTPCDESRSMFCHHGACVRLAPESLTKIDGQWGDWRSWGECSRTCGGGVQKGLRDCDSPKPRNGGKYCVGQRERYRSCNTQECPWDTQPYREVQCSEFNNKDIGIQGVASTNTHWVPKYANVAPNERCKLYCRLSGSAAFYLLRDKVVDGTPCDRNGDDICVAGACMPAGCDHQLHSTLRRDKCGVCGGDDSSCKVVKGTFNEQGTFGYNEV--MKIPAGSANIDI-----RQKGYNNMKEDDNYLSLRAANGEFLLNGHFQVSLARQQIAFQDTVLEYSGSDAIIERINGTGPIRSDIYVHVLSVGS-----HPPDISYEYMTAAVPNAVIRPISSALYLWRVTDTWTE-CDRACRGQQSQKLMCLDMSTHRQSHDRNCQNVLKPKQATRMCNIDCSTRW-------ITEDVS-SCSAKCGSGQKRQRVSCVKMEGDRQT-----PASEHLC---DRNSKPSDIASCYIDCSGRKWNYGEWTSCSETCGSNGKMHRKSYCVDDSNRRVDESLCGR-----EQKEATERECNRIPCPRWVYGHWSECSRSCDGGVKMRHAQC---------LDAADRETHTS--------RCGPAQTQEHCNEHACTWWQFGVWSDCSAKCGDGVQYRDANCTDR----HRSVLPEHR-CLKMEKIITKP------CHRESCPKYKL---GEWSQCSVSCEDGWSSRRVSCVSGNGTEV-----DMSLCGTASDRPASHQTCNLGTCPFWRNTDWSACSVSCGIGHRERTTECI--YREQSVDASFCGDTKMPETSQTCHLLP-CTSWKPSHWSPCSVTCGSGIQTRSVSCTRGSEGTIVDEYFCDRNTRPRLKKTCEKDTCDGPRVLQKLQADVPPIRWATGPWTACSATCGNGTQRRLLKCRDH-VRDLPDEYCNHLDKEVSTRNCRLRDC--SYWKMAEWEE--CPATCGTHVQQSRNVTCVSAEDGGRTILKDVDCDVQKRPTSARNCRLEPCPKGEEHI 1475

HSP 2 Score: 168.703 bits (426), Expect = 1.564e-41
Identity = 138/508 (27.17%), Postives = 215/508 (42.32%), Query Frame = 1 
Query: 3295 WIEMEWSKCSVSCGEGLQYRSLKCGYENENKTLTTWDNNEMCKNKMVPVSIQICKVTPCPKWIYSEWSECEGTCEYGSQHRTVLCTDPISEQILPDSKCDIKNKFPNFQKCLLSKLCGH-WIVGKWSQCSASCGLGVK-TRTITCNYSNGSKSIDHSVCKSVAPFEEIHCQVKPCSTNAFWWLVKPSECYEYNCQPGIMYAHVRC-----VNRKFQVLY---------DSKCSRIKHPSYYVGC-LNTTCRRYFWTAESWDNIPCPDISCTMKIRNRDVYCVDDYGNIQKDAMCDQSDKPDTWRLCPSPQNCSNIPRSCKELKSRQSVSKDGEYSLAIDLNWAYFIYCADMNTEEPKEYLTLR-ELNYARTSKYVSTDVSSCIYEEEMEFNQKCPTCKINENLWSITYYNKIRINLSDLSIDVMDDRFSATNGQSFIPFGTAKDCAGSTSCPKGHFKINLRGTGFSVSMETRWNEVYPKYGYRILRKQTSQIVKGWCGGHCSGCSPLK 4764
            W    WS CS  CG G + R ++C   + N T+ + +    C     PV    C+   CP+W  + WS C  TC  G + R V C     + ++ DS+C+ K K  +   C       + W V  WS+C   C  G K TR + C  ++G ++       + AP     C    C    + W+    +    +C  G+    VRC      N    +++           KC     P+    C LN     + W+   W        +C   IR R V CV + G   +   C  + KP   + C   +NC  +P +C+ELKS+   +KDG Y++ +D  +   IYC  MN+  PK YL +    N+A           +C +  +   N  C   +  +    +T +NK+RI+L +    + D  F+       +P+GTA DC     CP+G F I+L+  G  +  +  W +   +   RI R   +  V G CGG C  CSP +
Sbjct: 1625 WQTSAWSACSAKCGRGTKRRVVECVNPSLNVTVASTE----CDQTKKPVEEVRCRTKHCPRWKTTTWSSCSVTCGRGIRRREVQCYRG-RKNLVSDSECNPKTKLNSVANCFPVACPAYRWNVTPWSKCKDECARGQKQTRRVHCISTSGKRAAPRMCELARAPTSIRECDTSNC---PYEWVPGDWQTCSKSCGEGVQTREVRCRRKINFNSTIPIIFMLEDEPAVPKEKCELFPKPNESQTCELNPCDSEFKWSFGPWGEC---SKNCGQGIRRRRVKCVANDGRRVERVKC-TTKKPRRTQYC-FERNC--LPSTCQELKSQNVKAKDGNYTILLD-GFTIEIYCHRMNSTIPKAYLNVNPRTNFAEVYGKKLIYPHTCPFNGDR--NDSCHCSEDGDASAGLTRFNKVRIDLLNRKFHLADYTFAKREYGVHVPYGTAGDCYSMKDCPQGIFSIDLKSAGLKLVDDLNWEDQGHRTSSRIDRFYNNAKVIGHCGGFCGKCSPER 2114

HSP 3 Score: 135.191 bits (339), Expect = 2.803e-31
Identity = 135/517 (26.11%), Postives = 212/517 (41.01%), Query Frame = 1 
Query: 2701 WSYGKWEECPIECGTTFRYRNFICKDNKGLEWQKEWC---ERHLGLPDNKETCLSFNNCRNLTRWVTSPWSRCSNSCESELQKRMVYCFRSEKSDEILDEKFLKIHEQISDAFCDIHSPKPITERPCSLNSCYFWIXXXXXXXXXXXXLGFRIQSHECKKKFNKNHEMITVDDKFCLKQNLVKPLDVRMRCFLKKCAIESFWIEMEWSKCSVSCGEGLQYRSLKCGYENENKTLTTW--DNN-----------EMCKNKMVPVSIQICKVTPCPKWIYSEWSECEGTCEYGSQHRTVLCTDPISEQILPDSKCDIKNKFPNFQKCLLSKLCGHWIVGKWSQCSASCGLGVK-TRTITC-NYSNGSKSIDHSVCKSVA--PFEEIHCQVKPCSTN----AFWWLVKPSECYEYNCQPGIMYAHVRCVNRKFQVLYDSKCSRIKHPSYYVGCLNTTCRRYFWTAESWDNIPCP--DISCTMKIRNRDVYCVDDY-GNIQKDAMCDQSDKPDTWRLCPSP 4170
            W +G W +C  +CG   +YR+  C D       +  C   E+ +  P ++E+C  +             WS+CS SCE     R V C     +             ++  + C   S +P + + C+L +C FW  +    CS  CG+G R ++ EC  +        +VD  FC      K  +    C L  C   + W    WS CSV+CG G+Q RS+ C   +E   +  +  D N           + C    V   +Q     P  +W    W+ C  TC  G+Q R + C D + +  LPD  C+  +K  + + C L + C +W + +W +C A+CG  V+ +R +TC +  +G ++I   V   V   P    +C+++PC         W +   S+C   +C  G     V C +        S C   + P  +  C    C     T  SW   P     +SC   ++ R ++C D   G  Q D  C +  KP   R C  P
Sbjct: 1117 WQFGVWSDCSAKCGDGVQYRDANCTDRHRSVLPEHRCLKMEKIITKPCHRESCPKYK---------LGEWSQCSVSCEDGWSSRRVSCVSGNGT-------------EVDMSLCGTASDRPASHQTCNLGTCPFWRNTDWSACSVSCGIGHRERTTECIYREQ------SVDASFC---GDTKMPETSQTCHLLPC---TSWKPSHWSPCSVTCGSGIQTRSVSCTRGSEGTIVDEYFCDRNTRPRLKKTCEKDTCDGPRVLQKLQA--DVPPIRWATGPWTACSATCGNGTQRRLLKCRDHVRD--LPDEYCNHLDKEVSTRNCRL-RDCSYWKMAEWEECPATCGTHVQQSRNVTCVSAEDGGRTILKDVDCDVQKRPTSARNCRLEPCPKGEEHIGSWIIGDWSKC-SASCGGGWRRRSVSCTS--------SSCDETRKPKMFDKCNEELCPPL--TNNSWQISPWTHCSVSCGGGVQRRKIWCEDVLSGRKQDDIECSEI-KPREQRDCEMP 1582

HSP 4 Score: 124.79 bits (312), Expect = 3.553e-28
Identity = 146/574 (25.44%), Postives = 218/574 (37.98%), Query Frame = 1 
Query: 2614 VEENLCFAVDLVDRPIEELNC-VGQCNPLLWSYGKWEECPIECGTTFRYRNFICKDNKGLEWQKEWCERHLGLPDNKETCLSFNNCRNLTRWVTSPWSRCSNSCESELQKRMVYCFRSEKSDEILDEKFLKIHEQISDAFCDIHSPKPITERPCSLNSC---------------YFWIXXXXXXXXXXXXLGFRIQSHECKKKFNKNHEMITVDDKFCLKQNLVKPLDVRMRCFLKKCAIESFWIEMEWSKCSVSCGEGLQY-RSLKC-GYENENKTLTTWDNNEMCKNKMVPVSIQICKVTPCPK-------WIYSEWSECEGTCEYGSQHRTVLCTDPISEQILPDSKCDIKNKFPNFQKCLLSKLC-----GHWIVGKWSQCSASCGLGVKTRTITCNYSNGSKSIDHSVCKSVAPFEEIHCQVKPCSTN----------------------------------AFWWLVKPSECYEYNCQPGIMYAHVRCVNRKFQV-LYDSKCSRIKHPSYYVGCLNTTCRRYFWTAESWDNIPCPDISCTMKIRNRDVYCVDDYGNIQKDAMCDQSDK 4140
            V+ +LC      DRP     C +G C    W    W  C + CG   R R   C   +       +C     +P+  +TC         T W  S WS CS +C S +Q R V C R  +   I+DE            FCD ++ +P  ++ C  ++C                 W       CSA CG G + +  +C+           + D++C   +L K +  R  C L+ C   S+W   EW +C  +CG  +Q  R++ C   E+  +T+     +  C  +  P S + C++ PCPK       WI  +WS+C  +C  G + R+V CT          S CD   K   F KC   +LC       W +  W+ CS SCG GV+ R I C      +  D   C  + P E+  C++ PC ++                                     W           C  G     V CVN    V +  ++C + K P   V C    C R  W   +W +     ++C   IR R+V C     N+  D+ C+   K
Sbjct: 1203 VDMSLCGTAS--DRPASHQTCNLGTCP--FWRNTDWSACSVSCGIGHRERTTECI-YREQSVDASFCG-DTKMPETSQTCHLLP----CTSWKPSHWSPCSVTCGSGIQTRSVSCTRGSEG-TIVDE-----------YFCDRNT-RPRLKKTCEKDTCDGPRVLQKLQADVPPIRWATGPWTACSATCGNGTQRRLLKCRDHVRD------LPDEYC--NHLDKEVSTR-NCRLRDC---SYWKMAEWEECPATCGTHVQQSRNVTCVSAEDGGRTIL---KDVDCDVQKRPTSARNCRLEPCPKGEEHIGSWIIGDWSKCSASCGGGWRRRSVSCTS---------SSCDETRKPKMFDKCN-EELCPPLTNNSWQISPWTHCSVSCGGGVQRRKIWCEDVLSGRKQDDIECSEIKPREQRDCEMPPCRSHYHNKTSSASMTSLSSSNSNTTSSASASSLPILPPVVSWQTSAWSACSAKCGRGTKRRVVECVNPSLNVTVASTECDQTKKPVEEVRCRTKHCPR--WKTTTWSSC---SVTCGRGIRRREVQCYRGRKNLVSDSECNPKTK 1723

HSP 5 Score: 103.99 bits (258), Expect = 8.132e-22
Identity = 122/514 (23.74%), Postives = 190/514 (36.96%), Query Frame = 1 
Query: 2692 PLLWSYGKWEECPIECGTTFRYRNFICKDNKGLEWQKEWCERHLGLPDNKETCLSFNNCR--NLTRWVTSPWSRCSNSCESELQK-RMVYCFRSEKSDEILDEKFLKIHEQISDAFCDIHSPKPITERPCSLNSC-------YFWIXXXXXXXXXXXXLGFRIQSHECKKKFNKNHEMITVDDKFCLKQNLVKPLDVRMRCFLKKCAIESFWIEMEWSKCSVSCGEGLQYRSLKCGYENENKTLTTWDNNEMCKNKMVPVSIQICKVTPCPK--------------------------------------WIYSEWSECEGTCEYGSQHRTVLCTDPISEQILPDSKCDIKNKFPNFQKCLLSKLCGHWIVGKWSQCSASCGLGVKTRTITCNYSNGSKSIDHSVCKSVAPFEEIHCQVKPCSTNAFWWLVKP-SECYEYNCQPGIMYAHVRCVNRKFQVLYDSKCSRIKHPSYYVGCLNTTCRRYFWTAESWDNIPCPDISCTMKIRNRDVYC 4086
            P+ W+ G W  C   CG   + R   C+D+   +   E+C  HL    +KE  +S  NCR  + + W  + W  C  +C + +Q+ R V C  +E     +          + D  CD+   +P + R C L  C         WI     KCSA CG G+R +S  C            + DK    + L  PL              + W    W+ CSVSCG G+Q R + C        L+    +++  +++ P   + C++ PC                                        W  S WS C   C  G++ R V C +P     +  ++CD   K     +C  +K C  W    WS CS +CG G++ R + C Y      +  S C        +     P +  A+ W V P S+C +   +       V C++   +      C   + P+    C  + C  Y W    W        SC   ++ R+V C
Sbjct: 1353 PIRWATGPWTACSATCGNGTQRRLLKCRDHV-RDLPDEYCN-HL----DKE--VSTRNCRLRDCSYWKMAEWEECPATCGTHVQQSRNVTCVSAEDGGRTI----------LKDVDCDVQK-RPTSARNCRLEPCPKGEEHIGSWIIGDWSKCSASCGGGWRRRSVSCTSSSCDETRKPKMFDK--CNEELCPPL------------TNNSWQISPWTHCSVSCGGGVQRRKIWC-----EDVLSGRKQDDIECSEIKPREQRDCEMPPCRSHYHNKTSSASMTSLSSSNSNTTSSASASSLPILPPVVSWQTSAWSACSAKCGRGTKRRVVECVNPSLNVTVASTECDQTKKPVEEVRC-RTKHCPRWKTTTWSSCSVTCGRGIRRREVQC-YRGRKNLVSDSECNPKTKLNSV-ANCFPVACPAYRWNVTPWSKCKDECARGQKQTRRVHCISTSGKRAAPRMCELARAPTSIRECDTSNC-PYEWVPGDWQTC---SKSCGEGVQTREVRC 1821

HSP 6 Score: 68.5514 bits (166), Expect = 4.537e-11
Identity = 78/297 (26.26%), Postives = 120/297 (40.40%), Query Frame = 1 
Query: 2518 SCPIRCGTGKVKIPFVCQKINNQDDNNSLWETVEENLCFAVDLVDRPIEELNCVGQCNPLLWSYGKWEECPIECGTTFRYRNFIC-KDNKGLEWQKEWCERHLGLPDNKETCL-SFNNCRNLT----RWVTSPWSRCSNSC-ESELQKRMVYCFRSEKSDEILDEKFLKIHEQISDAFCDIHSPKPITERPCSLNSC-YFWIXXXXXXXXXXXXLGFRIQSHECKKKFNKNHEMITV----DDKFCLKQ--NLVKPLDVRMRCFLKKCAIESFWIEMEWSKCSVSCGEGLQYRSLKC 3366
            +C  +CG G  +    C        N SL  TV    C   D   +P+EE+ C  +  P  W    W  C + CG   R R   C +  K L    E          N +T L S  NC  +     RW  +PWS+C + C   + Q R V+C  +               ++ +   C++ +  P + R C  ++C Y W+      CS  CG G + +   C++K N N  +  +    D+    K+   L    +    C L  C  E  W    W +CS +CG+G++ R +KC
Sbjct: 1632 ACSAKCGRGTKRRVVECV-------NPSLNVTVASTEC---DQTKKPVEEVRCRTKHCPR-WKTTTWSSCSVTCGRGIRRREVQCYRGRKNLVSDSEC---------NPKTKLNSVANCFPVACPAYRWNVTPWSKCKDECARGQKQTRRVHCISTSG-------------KRAAPRMCEL-ARAPTSIRECDTSNCPYEWVPGDWQTCSKSCGEGVQTREVRCRRKINFNSTIPIIFMLEDEPAVPKEKCELFPKPNESQTCELNPCDSEFKWSFGPWGECSKNCGQGIRRRRVKC 1894
[Close]
BLAST of A disintegrin and metalloproteinase with thrombospondin motifs vs. Ensembl Celegans
Match: gon-1 (A disintegrin and metalloproteinase with thrombospondin motifs gon-1 [Source:UniProtKB/Swiss-Prot;Acc:Q19791])

HSP 1 Score: 317.775 bits (813), Expect = 2.727e-87
Identity = 335/1314 (25.49%), Postives = 514/1314 (39.12%), Query Frame = 1 
Query:  544 IELLIVVTSNFVKRFKKDFRQYILSNVAIATKLLHDPTIKASITXXXXXXXXXXEDYERNNDLHDWSLLSQDRVVSRFCHWVRQKKQLWNYSWDSAILINDGVF------------SSNAIGIAHLRSMCN-DNNCLAVVDRGFGTGFIIAHELAHQMNARHDFDNAEACSFFEKQYDNKTKYNTIMSTSLFFEYYPFIWSVCSQNVINSFLKSK--YSFCLKQRNRHRNLYPHEQINEFFQKYSTGVDYDLNEQCSFAFGEKSEFCETDQNSRKK-CSVLY-----CRLKRYPICLRADAIIADGTECDVNQH--CINGKCL-YKNITIAPIDGGWSEYSEWSNCSRPCNGGVQFSYRTCDNP---------------VPADGGRFCTGTKERIRSCNIEECSSFSDP-REESCGKYN-----LKPYIPTNDEEFP----------CNLVCITTNHSLKYDI--SLTDGTPCSPFRSDICVKGTCYKTGCDRIVGSKKAIDNCNICAGQNDTCFKKESFFDGSKVAKVRMIRAFRIPPNVYNLFIKKVSQRMTPFTDEVYDDFELLLVVNRRTVIRRSETIEPLAGGQ-------LRYSGSKNKVETISIKGKLNVGISI-VIKVENTKTTLNLPFISYHYFVKDI------------FVWKYLEVITHPCKDQCGGFIEISPACFKKRDNQRYVDHYCSKATKPEPKIIKCGAICGYRWQRATEHYINSTVNKSCPIRCGTGKVKIPFVCQKINNQDDNNSLWETVEENLCFAVDLVDRPIEELNCVGQCNPLLWSYGKWEECPIECGTTFR-YRNFICKDNKGLEWQKEWCERHLGLPDNKETCLSFNNCRNLTRWVTSPWSRCSNSCESELQKRMVYCFRSEKSDEILDEKFLKIHEQISDAFCDIHSPKPITERPCSLNSCYFWIXXXXXXXXXXXXLGFRIQSHECKKKFNKNHEMITVDDKFCLKQN--LVKPLDVRMRCFLKKCAIESFWIEMEWSKCSVSCGEGLQYRSLKCGYENENKTLTTWDNNEMCKNKM-VPVSIQICKVTPCPKWIYSEWSECEGTCEYGSQHRTVLCTDPISEQILPDSKCDIKNKFPNFQKCLLSKLCGHWIVGKWSQCSASCGLGVKTRTITCNYSNGSKSIDHSVC-KSVAPFEEIHCQVKPC-----------STNAFWWLVKPSECYEYNCQPGIMYAHVRCVNRKFQVLYDSKCSRIKHPSYYVGCLNTTCRRYFWTAESWDNIPCPDISCTMKIRNRDVYCV---DDYGNIQKDAMCDQSDKPDTWRLC---PSPQNCSNI 4188
            +E+L+V  +   +   +    Y+L+  +    +    +++ASI + VV +++L  +        +     QD     FC W    +Q +N   DS++  +D                 + +G+A L +MC+   +C  + D G    F IAHEL H  +  HD  +   CS +     NK  ++ IM+ +L +  +P+ WS CS  ++  FL++    + CL  +   R  Y      + F +   G  YD ++QC F FG  SE C      R+  C+  Y     CR +  P         ADGT CD ++   C +G C+     ++  IDG W ++  W  CSR C GGVQ   R CD+P                P +GG++C G +ER RSCN +EC   + P RE  C ++N     ++    TN    P          C L C  +  +  Y +   + DGTPC     DICV G C   GCD  + S    D C +C G + +C   +  F+         +   +IP    N+ I     R   + +   DD  L L       +        LA  Q       L YSGS   +E I+  G +   I + V+ V +     + P ISY Y    +            ++W+  +  T  C   C G       C     +++  D  C    KP+     C   C  RW       I   V+ SC  +CG+G+ +    C K+              E+LC   D   +P +  +C   C+   W+YG+W  C   CG+  + +R   C D+      +  C R     + KE      N     RWV   WS CS SC+  ++ R   C         LD    + H                T+  C+ ++C +W       CSAKCG G + +   C  +         + +  CLK    + KP      C  + C         EWS+CSVSC +G   R + C   N  +      +  +C      P S Q C +  CP W  ++WS C  +C  G + RT  C     EQ +  S C         Q C L   C  W    WS CS +CG G++TR+++C   +    +D   C ++  P  +  C+   C                 W   P       C  G     ++C +   + L D  C+ +        C    C   +W    W+   CP    T   ++R+V CV   D    I KD  CD   +P + R C   P P+   +I
Sbjct:  282 VEVLVVADTKMYEYHGRSLEDYVLTLFSTVASIYRHQSLRASINVVVVKLIVLKTENAGPRITQNAQQTLQD-----FCRW----QQYYNDPDDSSVQHHDVAILLTRKDICRSQGKCDTLGLAELGTMCDMQKSCAIIEDNGLSAAFTIAHELGHVFSIPHD--DERKCSTYMPV--NKNNFH-IMAPTLEYNTHPWSWSPCSAGMLERFLENNRGQTQCLFDQPVERRYY-----EDVFVRDEPGKKYDAHQQCKFVFGPASELCPYMPTCRRLWCATFYGSQMGCRTQHMPW--------ADGTPCDESRSMFCHHGACVRLAPESLTKIDGQWGDWRSWGECSRTCGGGVQKGLRDCDSPKSENEVETLKSNVTSRPRNGGKYCVGQRERYRSCNTQECPWDTQPYREVQCSEFNNKDIGIQGVASTNTHWVPKYANVAPNERCKLYCRLSGSAAFYLLRDKVVDGTPCDRNGDDICVAGACMPAGCDHQLHSTLRRDKCGVCGGDDSSCKVVKGTFNEQGTFGYNEV--MKIPAGSANIDI-----RQKGYNNMKEDDNYLSLRAANGEFLLNGHFQVSLARQQIAFQDTVLEYSGSDAIIERINGTGPIRSDIYVHVLSVGS-----HPPDISYEYMTAAVPNAVIRPISSALYLWRVTDTWTE-CDRACRGQQSQKLMCLDMSTHRQSHDRNCQNVLKPKQATRMCNIDCSTRW-------ITEDVS-SCSAKCGSGQKRQRVSCVKMEGDRQT-----PASEHLC---DRNSKPSDIASCYIDCSGRKWNYGEWTSCSETCGSNGKMHRKSYCVDDSNRRVDESLCGR-----EQKEATERECNRIPCPRWVYGHWSECSRSCDGGVKMRHAQC---------LDAADRETHTS--------RCGPAQTQEHCNEHACTWWQFGVWSDCSAKCGDGVQYRDANCTDRHRS-----VLPEHRCLKMEKIITKP------CHRESCPKYKL---GEWSQCSVSCEDGWSSRRVSCVSGNGTEV-----DMSLCGTASDRPASHQTCNLGTCPFWRNTDWSACSVSCGIGHRERTTECI--YREQSVDASFCGDTKMPETSQTCHLLP-CTSWKPSHWSPCSVTCGSGIQTRSVSCTRGSEGTIVDEYFCDRNTRPRLKKTCEKDTCDGPRVLQKLQADVPPIRWATGPWTACSATCGNGTQRRLLKCRDH-VRDLPDEYCNHLDKEVSTRNCRLRDC--SYWKMAEWEE--CPATCGTHVQQSRNVTCVSAEDGGRTILKDVDCDVQKRPTSARNCRLEPCPKGEEHI 1490

HSP 2 Score: 168.703 bits (426), Expect = 1.752e-41
Identity = 138/508 (27.17%), Postives = 215/508 (42.32%), Query Frame = 1 
Query: 3295 WIEMEWSKCSVSCGEGLQYRSLKCGYENENKTLTTWDNNEMCKNKMVPVSIQICKVTPCPKWIYSEWSECEGTCEYGSQHRTVLCTDPISEQILPDSKCDIKNKFPNFQKCLLSKLCGH-WIVGKWSQCSASCGLGVK-TRTITCNYSNGSKSIDHSVCKSVAPFEEIHCQVKPCSTNAFWWLVKPSECYEYNCQPGIMYAHVRC-----VNRKFQVLY---------DSKCSRIKHPSYYVGC-LNTTCRRYFWTAESWDNIPCPDISCTMKIRNRDVYCVDDYGNIQKDAMCDQSDKPDTWRLCPSPQNCSNIPRSCKELKSRQSVSKDGEYSLAIDLNWAYFIYCADMNTEEPKEYLTLR-ELNYARTSKYVSTDVSSCIYEEEMEFNQKCPTCKINENLWSITYYNKIRINLSDLSIDVMDDRFSATNGQSFIPFGTAKDCAGSTSCPKGHFKINLRGTGFSVSMETRWNEVYPKYGYRILRKQTSQIVKGWCGGHCSGCSPLK 4764
            W    WS CS  CG G + R ++C   + N T+ + +    C     PV    C+   CP+W  + WS C  TC  G + R V C     + ++ DS+C+ K K  +   C       + W V  WS+C   C  G K TR + C  ++G ++       + AP     C    C    + W+    +    +C  G+    VRC      N    +++           KC     P+    C LN     + W+   W        +C   IR R V CV + G   +   C  + KP   + C   +NC  +P +C+ELKS+   +KDG Y++ +D  +   IYC  MN+  PK YL +    N+A           +C +  +   N  C   +  +    +T +NK+RI+L +    + D  F+       +P+GTA DC     CP+G F I+L+  G  +  +  W +   +   RI R   +  V G CGG C  CSP +
Sbjct: 1640 WQTSAWSACSAKCGRGTKRRVVECVNPSLNVTVASTE----CDQTKKPVEEVRCRTKHCPRWKTTTWSSCSVTCGRGIRRREVQCYRG-RKNLVSDSECNPKTKLNSVANCFPVACPAYRWNVTPWSKCKDECARGQKQTRRVHCISTSGKRAAPRMCELARAPTSIRECDTSNC---PYEWVPGDWQTCSKSCGEGVQTREVRCRRKINFNSTIPIIFMLEDEPAVPKEKCELFPKPNESQTCELNPCDSEFKWSFGPWGEC---SKNCGQGIRRRRVKCVANDGRRVERVKC-TTKKPRRTQYC-FERNC--LPSTCQELKSQNVKAKDGNYTILLD-GFTIEIYCHRMNSTIPKAYLNVNPRTNFAEVYGKKLIYPHTCPFNGDR--NDSCHCSEDGDASAGLTRFNKVRIDLLNRKFHLADYTFAKREYGVHVPYGTAGDCYSMKDCPQGIFSIDLKSAGLKLVDDLNWEDQGHRTSSRIDRFYNNAKVIGHCGGFCGKCSPER 2129

HSP 3 Score: 135.191 bits (339), Expect = 3.084e-31
Identity = 135/517 (26.11%), Postives = 212/517 (41.01%), Query Frame = 1 
Query: 2701 WSYGKWEECPIECGTTFRYRNFICKDNKGLEWQKEWC---ERHLGLPDNKETCLSFNNCRNLTRWVTSPWSRCSNSCESELQKRMVYCFRSEKSDEILDEKFLKIHEQISDAFCDIHSPKPITERPCSLNSCYFWIXXXXXXXXXXXXLGFRIQSHECKKKFNKNHEMITVDDKFCLKQNLVKPLDVRMRCFLKKCAIESFWIEMEWSKCSVSCGEGLQYRSLKCGYENENKTLTTW--DNN-----------EMCKNKMVPVSIQICKVTPCPKWIYSEWSECEGTCEYGSQHRTVLCTDPISEQILPDSKCDIKNKFPNFQKCLLSKLCGHWIVGKWSQCSASCGLGVK-TRTITC-NYSNGSKSIDHSVCKSVA--PFEEIHCQVKPCSTN----AFWWLVKPSECYEYNCQPGIMYAHVRCVNRKFQVLYDSKCSRIKHPSYYVGCLNTTCRRYFWTAESWDNIPCP--DISCTMKIRNRDVYCVDDY-GNIQKDAMCDQSDKPDTWRLCPSP 4170
            W +G W +C  +CG   +YR+  C D       +  C   E+ +  P ++E+C  +             WS+CS SCE     R V C     +             ++  + C   S +P + + C+L +C FW  +    CS  CG+G R ++ EC  +        +VD  FC      K  +    C L  C   + W    WS CSV+CG G+Q RS+ C   +E   +  +  D N           + C    V   +Q     P  +W    W+ C  TC  G+Q R + C D + +  LPD  C+  +K  + + C L + C +W + +W +C A+CG  V+ +R +TC +  +G ++I   V   V   P    +C+++PC         W +   S+C   +C  G     V C +        S C   + P  +  C    C     T  SW   P     +SC   ++ R ++C D   G  Q D  C +  KP   R C  P
Sbjct: 1132 WQFGVWSDCSAKCGDGVQYRDANCTDRHRSVLPEHRCLKMEKIITKPCHRESCPKYK---------LGEWSQCSVSCEDGWSSRRVSCVSGNGT-------------EVDMSLCGTASDRPASHQTCNLGTCPFWRNTDWSACSVSCGIGHRERTTECIYREQ------SVDASFC---GDTKMPETSQTCHLLPC---TSWKPSHWSPCSVTCGSGIQTRSVSCTRGSEGTIVDEYFCDRNTRPRLKKTCEKDTCDGPRVLQKLQA--DVPPIRWATGPWTACSATCGNGTQRRLLKCRDHVRD--LPDEYCNHLDKEVSTRNCRL-RDCSYWKMAEWEECPATCGTHVQQSRNVTCVSAEDGGRTILKDVDCDVQKRPTSARNCRLEPCPKGEEHIGSWIIGDWSKC-SASCGGGWRRRSVSCTS--------SSCDETRKPKMFDKCNEELCPPL--TNNSWQISPWTHCSVSCGGGVQRRKIWCEDVLSGRKQDDIECSEI-KPREQRDCEMP 1597

HSP 4 Score: 124.79 bits (312), Expect = 3.778e-28
Identity = 146/574 (25.44%), Postives = 218/574 (37.98%), Query Frame = 1 
Query: 2614 VEENLCFAVDLVDRPIEELNC-VGQCNPLLWSYGKWEECPIECGTTFRYRNFICKDNKGLEWQKEWCERHLGLPDNKETCLSFNNCRNLTRWVTSPWSRCSNSCESELQKRMVYCFRSEKSDEILDEKFLKIHEQISDAFCDIHSPKPITERPCSLNSC---------------YFWIXXXXXXXXXXXXLGFRIQSHECKKKFNKNHEMITVDDKFCLKQNLVKPLDVRMRCFLKKCAIESFWIEMEWSKCSVSCGEGLQY-RSLKC-GYENENKTLTTWDNNEMCKNKMVPVSIQICKVTPCPK-------WIYSEWSECEGTCEYGSQHRTVLCTDPISEQILPDSKCDIKNKFPNFQKCLLSKLC-----GHWIVGKWSQCSASCGLGVKTRTITCNYSNGSKSIDHSVCKSVAPFEEIHCQVKPCSTN----------------------------------AFWWLVKPSECYEYNCQPGIMYAHVRCVNRKFQV-LYDSKCSRIKHPSYYVGCLNTTCRRYFWTAESWDNIPCPDISCTMKIRNRDVYCVDDYGNIQKDAMCDQSDK 4140
            V+ +LC      DRP     C +G C    W    W  C + CG   R R   C   +       +C     +P+  +TC         T W  S WS CS +C S +Q R V C R  +   I+DE            FCD ++ +P  ++ C  ++C                 W       CSA CG G + +  +C+           + D++C   +L K +  R  C L+ C   S+W   EW +C  +CG  +Q  R++ C   E+  +T+     +  C  +  P S + C++ PCPK       WI  +WS+C  +C  G + R+V CT          S CD   K   F KC   +LC       W +  W+ CS SCG GV+ R I C      +  D   C  + P E+  C++ PC ++                                     W           C  G     V CVN    V +  ++C + K P   V C    C R  W   +W +     ++C   IR R+V C     N+  D+ C+   K
Sbjct: 1218 VDMSLCGTAS--DRPASHQTCNLGTCP--FWRNTDWSACSVSCGIGHRERTTECI-YREQSVDASFCG-DTKMPETSQTCHLLP----CTSWKPSHWSPCSVTCGSGIQTRSVSCTRGSEG-TIVDE-----------YFCDRNT-RPRLKKTCEKDTCDGPRVLQKLQADVPPIRWATGPWTACSATCGNGTQRRLLKCRDHVRD------LPDEYC--NHLDKEVSTR-NCRLRDC---SYWKMAEWEECPATCGTHVQQSRNVTCVSAEDGGRTIL---KDVDCDVQKRPTSARNCRLEPCPKGEEHIGSWIIGDWSKCSASCGGGWRRRSVSCTS---------SSCDETRKPKMFDKCN-EELCPPLTNNSWQISPWTHCSVSCGGGVQRRKIWCEDVLSGRKQDDIECSEIKPREQRDCEMPPCRSHYHNKTSSASMTSLSSSNSNTTSSASASSLPILPPVVSWQTSAWSACSAKCGRGTKRRVVECVNPSLNVTVASTECDQTKKPVEEVRCRTKHCPR--WKTTTWSSC---SVTCGRGIRRREVQCYRGRKNLVSDSECNPKTK 1738

HSP 5 Score: 103.99 bits (258), Expect = 8.642e-22
Identity = 122/514 (23.74%), Postives = 190/514 (36.96%), Query Frame = 1 
Query: 2692 PLLWSYGKWEECPIECGTTFRYRNFICKDNKGLEWQKEWCERHLGLPDNKETCLSFNNCR--NLTRWVTSPWSRCSNSCESELQK-RMVYCFRSEKSDEILDEKFLKIHEQISDAFCDIHSPKPITERPCSLNSC-------YFWIXXXXXXXXXXXXLGFRIQSHECKKKFNKNHEMITVDDKFCLKQNLVKPLDVRMRCFLKKCAIESFWIEMEWSKCSVSCGEGLQYRSLKCGYENENKTLTTWDNNEMCKNKMVPVSIQICKVTPCPK--------------------------------------WIYSEWSECEGTCEYGSQHRTVLCTDPISEQILPDSKCDIKNKFPNFQKCLLSKLCGHWIVGKWSQCSASCGLGVKTRTITCNYSNGSKSIDHSVCKSVAPFEEIHCQVKPCSTNAFWWLVKP-SECYEYNCQPGIMYAHVRCVNRKFQVLYDSKCSRIKHPSYYVGCLNTTCRRYFWTAESWDNIPCPDISCTMKIRNRDVYC 4086
            P+ W+ G W  C   CG   + R   C+D+   +   E+C  HL    +KE  +S  NCR  + + W  + W  C  +C + +Q+ R V C  +E     +          + D  CD+   +P + R C L  C         WI     KCSA CG G+R +S  C            + DK    + L  PL              + W    W+ CSVSCG G+Q R + C        L+    +++  +++ P   + C++ PC                                        W  S WS C   C  G++ R V C +P     +  ++CD   K     +C  +K C  W    WS CS +CG G++ R + C Y      +  S C        +     P +  A+ W V P S+C +   +       V C++   +      C   + P+    C  + C  Y W    W        SC   ++ R+V C
Sbjct: 1368 PIRWATGPWTACSATCGNGTQRRLLKCRDHV-RDLPDEYCN-HL----DKE--VSTRNCRLRDCSYWKMAEWEECPATCGTHVQQSRNVTCVSAEDGGRTI----------LKDVDCDVQK-RPTSARNCRLEPCPKGEEHIGSWIIGDWSKCSASCGGGWRRRSVSCTSSSCDETRKPKMFDK--CNEELCPPL------------TNNSWQISPWTHCSVSCGGGVQRRKIWC-----EDVLSGRKQDDIECSEIKPREQRDCEMPPCRSHYHNKTSSASMTSLSSSNSNTTSSASASSLPILPPVVSWQTSAWSACSAKCGRGTKRRVVECVNPSLNVTVASTECDQTKKPVEEVRC-RTKHCPRWKTTTWSSCSVTCGRGIRRREVQC-YRGRKNLVSDSECNPKTKLNSV-ANCFPVACPAYRWNVTPWSKCKDECARGQKQTRRVHCISTSGKRAAPRMCELARAPTSIRECDTSNC-PYEWVPGDWQTC---SKSCGEGVQTREVRC 1836

HSP 6 Score: 68.5514 bits (166), Expect = 4.983e-11
Identity = 78/297 (26.26%), Postives = 120/297 (40.40%), Query Frame = 1 
Query: 2518 SCPIRCGTGKVKIPFVCQKINNQDDNNSLWETVEENLCFAVDLVDRPIEELNCVGQCNPLLWSYGKWEECPIECGTTFRYRNFIC-KDNKGLEWQKEWCERHLGLPDNKETCL-SFNNCRNLT----RWVTSPWSRCSNSC-ESELQKRMVYCFRSEKSDEILDEKFLKIHEQISDAFCDIHSPKPITERPCSLNSC-YFWIXXXXXXXXXXXXLGFRIQSHECKKKFNKNHEMITV----DDKFCLKQ--NLVKPLDVRMRCFLKKCAIESFWIEMEWSKCSVSCGEGLQYRSLKC 3366
            +C  +CG G  +    C        N SL  TV    C   D   +P+EE+ C  +  P  W    W  C + CG   R R   C +  K L    E          N +T L S  NC  +     RW  +PWS+C + C   + Q R V+C  +               ++ +   C++ +  P + R C  ++C Y W+      CS  CG G + +   C++K N N  +  +    D+    K+   L    +    C L  C  E  W    W +CS +CG+G++ R +KC
Sbjct: 1647 ACSAKCGRGTKRRVVECV-------NPSLNVTVASTEC---DQTKKPVEEVRCRTKHCPR-WKTTTWSSCSVTCGRGIRRREVQCYRGRKNLVSDSEC---------NPKTKLNSVANCFPVACPAYRWNVTPWSKCKDECARGQKQTRRVHCISTSG-------------KRAAPRMCEL-ARAPTSIRECDTSNCPYEWVPGDWQTCSKSCGEGVQTREVRCRRKINFNSTIPIIFMLEDEPAVPKEKCELFPKPNESQTCELNPCDSEFKWSFGPWGECSKNCGQGIRRRRVKC 1909
[Close]
BLAST of A disintegrin and metalloproteinase with thrombospondin motifs vs. Ensembl Celegans
Match: mig-6 (Papilin [Source:UniProtKB/Swiss-Prot;Acc:O76840])

HSP 1 Score: 137.117 bits (344), Expect = 6.653e-32
Identity = 177/697 (25.39%), Postives = 268/697 (38.45%), Query Frame = 1 
Query: 1474 GGWSEYSEWSNCSRPCNGGVQFSYRTCDNPVPADGGRFCTGTKERIRSCNIEECSSFSDPREESCGKYNLK----------PYIPTNDEEFPCNLVCI--TTNHSLKYDISLTDGTPCSPFRSDICVKGTCYKTGCDRIVGSKKAIDNCNICAGQNDTCFKKESFFDGSKVAKVRMIRAFRIPPNVYNLFIKKVSQRMTPFTDEVYDDFELLLVVNRRTVIRRSETIEPLAGGQLRYSGSKNKVETISIKGKLNVGISIVIKVENTKTTLNLPFISYHYFVKDIFVWKYLEVITHPCKDQCGGFIEISPA-CFKKRDNQRYVDHYCSK--ATKPEPKIIKCGAICGYRWQRATEHYINSTVNKSCPIRCGTGKVKIPFV-CQKINNQDDNNSLWETVEENLCFAVDLVDRPIEELNCVGQCNPLLWSYGKWEECPIECGTTFRYRNFICKDNKGLEWQK----EWCERHLGLPDNKETCLSFNNCRNLTRWVTSPWSRCSNSCESELQKRMVYCFRSEKSDEILDEKFLKIHEQISDAFCDIHSPKPITERPCSLNSCYFWIXXXXXXXXXXXXLGFRIQSHECKKKFNKNHEMITVDDKFCLKQNLVKPLDVRMRCFLKKCAIESFWIEMEWSKCSVSCGEGLQYRSLKCGYENENKTLTTWDNNEMCKNKMVPVSIQICKVTPCPKWIYSEWSEC 3504
            G W  +   + CSR C GGVQ   R C           CTG   R  SCN+  C S +D R E C K+N +          PY   N     C LVC   + N   K+   + DGT C    +DICV G C   GCD  +GS    D C  C G   TC   E  FD   ++        ++P    N+ I++  +       +   D      +N   +I+  + +E + G    Y  +  + ET+S +G L+  +++ +          + +  +   +++   + Y      PC   CG  ++     C   ++  R  D  C +  ATKPE +       C   W             +SC   CG    +   V C ++      N    TVE+  C     V+RP  +  C     P  W  G W  C  +CG  F+YR+  C+  K  E  K    + C        + E   +   C  LT +VT  W+ C+  C    + R V C  S+     L++  +    +I        +    T+ PC     Y W  S+  KC+ +CG G + +   C    ++N  +  VD+  C  +   KP         +KC     W    WS+C+  CG G Q R   C    + K +  W     C   + P   Q C V  CP  + SE+  C
Sbjct:   77 GNWGPWVPENECSRSCGGGVQLEKRQCSGD--------CTGASVRYISCNLNACESGTDFRAEQCSKFNDEALDGNYHKWTPYKGKNK----CELVCKPESGNFYYKWADKVVDGTKCDSKSNDICVDGECLPVGCDGKLGSSLKFDKCGKCDGDGSTCKTIEGRFDERNLSP-GYHDIIKLPEGATNIKIQEARKSTNNLALKNGSDH---FYLNGNGLIQVEKEVE-VGGTIFVYDDA--EPETLSAQGPLSEELTVALLFRKGSRDTAIKY-EFSIPLEEEVDYMYKFDNWTPCSVSCGKGVQTRNLYCIDGKNKGRVEDDLCEENNATKPEFEKSCETVDCEAEWFTGDW--------ESCSSTCGDQGQQYRVVYCHQVF----ANGRRVTVEDGNC----TVERPPVKQTCNRFACP-EWQAGPWSACSEKCGDAFQYRSVTCRSEKEGEEGKLLAADACPADEQEKFDTERTCNLGPCEGLT-FVTGEWNLCTR-CNDTEETREVTCKDSQGRAYPLEKCLVDNSTEIP-----TDTRSCATQPPCE----YEWTVSEWSKCTTECGHGHKTRRVIC--AIHQNGGLEVVDEGHCQAE---KPEGKTNCTNEEKCT--GTWYTSSWSECTAECGGGSQDRVAVC-LNYDKKPVPEW-----CDEAVKPSEKQDCNVDDCPTCVDSEFGCC 712

HSP 2 Score: 75.0998 bits (183), Expect = 4.276e-13
Identity = 84/331 (25.38%), Postives = 134/331 (40.48%), Query Frame = 1 
Query: 2899 WSRCSNSCESELQKRMVYCFRSEKSDEILDEKFLKIHEQISDAFCDIH-SPKPITERPCSLNSCY--FWIXXXXXXXXXXXXLGFRIQSHECKKKFNKNHEMITVDDKFCLKQNLVKPLDVRMRCFLKKCAIESFWIEMEWSKCSVSCGEGLQYRSLKCGYENENKTLTTWDNNEMCKNKMVPVSIQ-ICKVTPCPK--WIYSEWSECEGTCEYGSQHRTVLCTDPISEQILPDSKCDIKN--KFP-NFQKCLLSKLCGH-WIVGKWSQCSASCGLGVKTRTITC--NYSNGSKSIDHSVCKSVAPFEEIHCQVKPCSTNAFWWLVKPSEC 3855
            W+ CS SC   +Q R +YC               K   ++ D  C+ + + KP  E+ C    C   ++        S     G + +   C + F  N   +TV+D  C     V+   V+  C    C     W    WS CS  CG+  QYRS+ C  E E +       +    ++      +  C + PC    ++  EW+ C   C    + R V C D    +  P  KC + N  + P + + C     C + W V +WS+C+  CG G KTR + C  + + G + +D   C++  P  + +C  +   T   W+    SEC
Sbjct:  350 WTPCSVSCGKGVQTRNLYCIDG------------KNKGRVEDDLCEENNATKPEFEKSCETVDCEAEWFTGDWESCSSTCGDQGQQYRVVYCHQVF-ANGRRVTVEDGNCT----VERPPVKQTCNRFACPE---WQAGPWSACSEKCGDAFQYRSVTCRSEKEGEEGKLLAADACPADEQEKFDTERTCNLGPCEGLTFVTGEWNLCT-RCNDTEETREVTCKDSQG-RAYPLEKCLVDNSTEIPTDTRSCATQPPCEYEWTVSEWSKCTTECGHGHKTRRVICAIHQNGGLEVVDEGHCQAEKPEGKTNCTNEEKCTGT-WYTSSWSEC 657
[Close]
BLAST of A disintegrin and metalloproteinase with thrombospondin motifs vs. Ensembl Celegans
Match: mig-6 (Papilin [Source:UniProtKB/Swiss-Prot;Acc:O76840])

HSP 1 Score: 137.117 bits (344), Expect = 6.653e-32
Identity = 177/697 (25.39%), Postives = 268/697 (38.45%), Query Frame = 1 
Query: 1474 GGWSEYSEWSNCSRPCNGGVQFSYRTCDNPVPADGGRFCTGTKERIRSCNIEECSSFSDPREESCGKYNLK----------PYIPTNDEEFPCNLVCI--TTNHSLKYDISLTDGTPCSPFRSDICVKGTCYKTGCDRIVGSKKAIDNCNICAGQNDTCFKKESFFDGSKVAKVRMIRAFRIPPNVYNLFIKKVSQRMTPFTDEVYDDFELLLVVNRRTVIRRSETIEPLAGGQLRYSGSKNKVETISIKGKLNVGISIVIKVENTKTTLNLPFISYHYFVKDIFVWKYLEVITHPCKDQCGGFIEISPA-CFKKRDNQRYVDHYCSK--ATKPEPKIIKCGAICGYRWQRATEHYINSTVNKSCPIRCGTGKVKIPFV-CQKINNQDDNNSLWETVEENLCFAVDLVDRPIEELNCVGQCNPLLWSYGKWEECPIECGTTFRYRNFICKDNKGLEWQK----EWCERHLGLPDNKETCLSFNNCRNLTRWVTSPWSRCSNSCESELQKRMVYCFRSEKSDEILDEKFLKIHEQISDAFCDIHSPKPITERPCSLNSCYFWIXXXXXXXXXXXXLGFRIQSHECKKKFNKNHEMITVDDKFCLKQNLVKPLDVRMRCFLKKCAIESFWIEMEWSKCSVSCGEGLQYRSLKCGYENENKTLTTWDNNEMCKNKMVPVSIQICKVTPCPKWIYSEWSEC 3504
            G W  +   + CSR C GGVQ   R C           CTG   R  SCN+  C S +D R E C K+N +          PY   N     C LVC   + N   K+   + DGT C    +DICV G C   GCD  +GS    D C  C G   TC   E  FD   ++        ++P    N+ I++  +       +   D      +N   +I+  + +E + G    Y  +  + ET+S +G L+  +++ +          + +  +   +++   + Y      PC   CG  ++     C   ++  R  D  C +  ATKPE +       C   W             +SC   CG    +   V C ++      N    TVE+  C     V+RP  +  C     P  W  G W  C  +CG  F+YR+  C+  K  E  K    + C        + E   +   C  LT +VT  W+ C+  C    + R V C  S+     L++  +    +I        +    T+ PC     Y W  S+  KC+ +CG G + +   C    ++N  +  VD+  C  +   KP         +KC     W    WS+C+  CG G Q R   C    + K +  W     C   + P   Q C V  CP  + SE+  C
Sbjct:   77 GNWGPWVPENECSRSCGGGVQLEKRQCSGD--------CTGASVRYISCNLNACESGTDFRAEQCSKFNDEALDGNYHKWTPYKGKNK----CELVCKPESGNFYYKWADKVVDGTKCDSKSNDICVDGECLPVGCDGKLGSSLKFDKCGKCDGDGSTCKTIEGRFDERNLSP-GYHDIIKLPEGATNIKIQEARKSTNNLALKNGSDH---FYLNGNGLIQVEKEVE-VGGTIFVYDDA--EPETLSAQGPLSEELTVALLFRKGSRDTAIKY-EFSIPLEEEVDYMYKFDNWTPCSVSCGKGVQTRNLYCIDGKNKGRVEDDLCEENNATKPEFEKSCETVDCEAEWFTGDW--------ESCSSTCGDQGQQYRVVYCHQVF----ANGRRVTVEDGNC----TVERPPVKQTCNRFACP-EWQAGPWSACSEKCGDAFQYRSVTCRSEKEGEEGKLLAADACPADEQEKFDTERTCNLGPCEGLT-FVTGEWNLCTR-CNDTEETREVTCKDSQGRAYPLEKCLVDNSTEIP-----TDTRSCATQPPCE----YEWTVSEWSKCTTECGHGHKTRRVIC--AIHQNGGLEVVDEGHCQAE---KPEGKTNCTNEEKCT--GTWYTSSWSECTAECGGGSQDRVAVC-LNYDKKPVPEW-----CDEAVKPSEKQDCNVDDCPTCVDSEFGCC 712

HSP 2 Score: 75.0998 bits (183), Expect = 4.276e-13
Identity = 84/331 (25.38%), Postives = 134/331 (40.48%), Query Frame = 1 
Query: 2899 WSRCSNSCESELQKRMVYCFRSEKSDEILDEKFLKIHEQISDAFCDIH-SPKPITERPCSLNSCY--FWIXXXXXXXXXXXXLGFRIQSHECKKKFNKNHEMITVDDKFCLKQNLVKPLDVRMRCFLKKCAIESFWIEMEWSKCSVSCGEGLQYRSLKCGYENENKTLTTWDNNEMCKNKMVPVSIQ-ICKVTPCPK--WIYSEWSECEGTCEYGSQHRTVLCTDPISEQILPDSKCDIKN--KFP-NFQKCLLSKLCGH-WIVGKWSQCSASCGLGVKTRTITC--NYSNGSKSIDHSVCKSVAPFEEIHCQVKPCSTNAFWWLVKPSEC 3855
            W+ CS SC   +Q R +YC               K   ++ D  C+ + + KP  E+ C    C   ++        S     G + +   C + F  N   +TV+D  C     V+   V+  C    C     W    WS CS  CG+  QYRS+ C  E E +       +    ++      +  C + PC    ++  EW+ C   C    + R V C D    +  P  KC + N  + P + + C     C + W V +WS+C+  CG G KTR + C  + + G + +D   C++  P  + +C  +   T   W+    SEC
Sbjct:  350 WTPCSVSCGKGVQTRNLYCIDG------------KNKGRVEDDLCEENNATKPEFEKSCETVDCEAEWFTGDWESCSSTCGDQGQQYRVVYCHQVF-ANGRRVTVEDGNCT----VERPPVKQTCNRFACPE---WQAGPWSACSEKCGDAFQYRSVTCRSEKEGEEGKLLAADACPADEQEKFDTERTCNLGPCEGLTFVTGEWNLCT-RCNDTEETREVTCKDSQG-RAYPLEKCLVDNSTEIPTDTRSCATQPPCEYEWTVSEWSKCTTECGHGHKTRRVICAIHQNGGLEVVDEGHCQAEKPEGKTNCTNEEKCTGT-WYTSSWSEC 657
[Close]
BLAST of A disintegrin and metalloproteinase with thrombospondin motifs vs. Ensembl Celegans
Match: mig-6 (Papilin [Source:UniProtKB/Swiss-Prot;Acc:O76840])

HSP 1 Score: 137.117 bits (344), Expect = 6.653e-32
Identity = 177/697 (25.39%), Postives = 268/697 (38.45%), Query Frame = 1 
Query: 1474 GGWSEYSEWSNCSRPCNGGVQFSYRTCDNPVPADGGRFCTGTKERIRSCNIEECSSFSDPREESCGKYNLK----------PYIPTNDEEFPCNLVCI--TTNHSLKYDISLTDGTPCSPFRSDICVKGTCYKTGCDRIVGSKKAIDNCNICAGQNDTCFKKESFFDGSKVAKVRMIRAFRIPPNVYNLFIKKVSQRMTPFTDEVYDDFELLLVVNRRTVIRRSETIEPLAGGQLRYSGSKNKVETISIKGKLNVGISIVIKVENTKTTLNLPFISYHYFVKDIFVWKYLEVITHPCKDQCGGFIEISPA-CFKKRDNQRYVDHYCSK--ATKPEPKIIKCGAICGYRWQRATEHYINSTVNKSCPIRCGTGKVKIPFV-CQKINNQDDNNSLWETVEENLCFAVDLVDRPIEELNCVGQCNPLLWSYGKWEECPIECGTTFRYRNFICKDNKGLEWQK----EWCERHLGLPDNKETCLSFNNCRNLTRWVTSPWSRCSNSCESELQKRMVYCFRSEKSDEILDEKFLKIHEQISDAFCDIHSPKPITERPCSLNSCYFWIXXXXXXXXXXXXLGFRIQSHECKKKFNKNHEMITVDDKFCLKQNLVKPLDVRMRCFLKKCAIESFWIEMEWSKCSVSCGEGLQYRSLKCGYENENKTLTTWDNNEMCKNKMVPVSIQICKVTPCPKWIYSEWSEC 3504
            G W  +   + CSR C GGVQ   R C           CTG   R  SCN+  C S +D R E C K+N +          PY   N     C LVC   + N   K+   + DGT C    +DICV G C   GCD  +GS    D C  C G   TC   E  FD   ++        ++P    N+ I++  +       +   D      +N   +I+  + +E + G    Y  +  + ET+S +G L+  +++ +          + +  +   +++   + Y      PC   CG  ++     C   ++  R  D  C +  ATKPE +       C   W             +SC   CG    +   V C ++      N    TVE+  C     V+RP  +  C     P  W  G W  C  +CG  F+YR+  C+  K  E  K    + C        + E   +   C  LT +VT  W+ C+  C    + R V C  S+     L++  +    +I        +    T+ PC     Y W  S+  KC+ +CG G + +   C    ++N  +  VD+  C  +   KP         +KC     W    WS+C+  CG G Q R   C    + K +  W     C   + P   Q C V  CP  + SE+  C
Sbjct:   77 GNWGPWVPENECSRSCGGGVQLEKRQCSGD--------CTGASVRYISCNLNACESGTDFRAEQCSKFNDEALDGNYHKWTPYKGKNK----CELVCKPESGNFYYKWADKVVDGTKCDSKSNDICVDGECLPVGCDGKLGSSLKFDKCGKCDGDGSTCKTIEGRFDERNLSP-GYHDIIKLPEGATNIKIQEARKSTNNLALKNGSDH---FYLNGNGLIQVEKEVE-VGGTIFVYDDA--EPETLSAQGPLSEELTVALLFRKGSRDTAIKY-EFSIPLEEEVDYMYKFDNWTPCSVSCGKGVQTRNLYCIDGKNKGRVEDDLCEENNATKPEFEKSCETVDCEAEWFTGDW--------ESCSSTCGDQGQQYRVVYCHQVF----ANGRRVTVEDGNC----TVERPPVKQTCNRFACP-EWQAGPWSACSEKCGDAFQYRSVTCRSEKEGEEGKLLAADACPADEQEKFDTERTCNLGPCEGLT-FVTGEWNLCTR-CNDTEETREVTCKDSQGRAYPLEKCLVDNSTEIP-----TDTRSCATQPPCE----YEWTVSEWSKCTTECGHGHKTRRVIC--AIHQNGGLEVVDEGHCQAE---KPEGKTNCTNEEKCT--GTWYTSSWSECTAECGGGSQDRVAVC-LNYDKKPVPEW-----CDEAVKPSEKQDCNVDDCPTCVDSEFGCC 712

HSP 2 Score: 75.0998 bits (183), Expect = 4.276e-13
Identity = 84/331 (25.38%), Postives = 134/331 (40.48%), Query Frame = 1 
Query: 2899 WSRCSNSCESELQKRMVYCFRSEKSDEILDEKFLKIHEQISDAFCDIH-SPKPITERPCSLNSCY--FWIXXXXXXXXXXXXLGFRIQSHECKKKFNKNHEMITVDDKFCLKQNLVKPLDVRMRCFLKKCAIESFWIEMEWSKCSVSCGEGLQYRSLKCGYENENKTLTTWDNNEMCKNKMVPVSIQ-ICKVTPCPK--WIYSEWSECEGTCEYGSQHRTVLCTDPISEQILPDSKCDIKN--KFP-NFQKCLLSKLCGH-WIVGKWSQCSASCGLGVKTRTITC--NYSNGSKSIDHSVCKSVAPFEEIHCQVKPCSTNAFWWLVKPSEC 3855
            W+ CS SC   +Q R +YC               K   ++ D  C+ + + KP  E+ C    C   ++        S     G + +   C + F  N   +TV+D  C     V+   V+  C    C     W    WS CS  CG+  QYRS+ C  E E +       +    ++      +  C + PC    ++  EW+ C   C    + R V C D    +  P  KC + N  + P + + C     C + W V +WS+C+  CG G KTR + C  + + G + +D   C++  P  + +C  +   T   W+    SEC
Sbjct:  350 WTPCSVSCGKGVQTRNLYCIDG------------KNKGRVEDDLCEENNATKPEFEKSCETVDCEAEWFTGDWESCSSTCGDQGQQYRVVYCHQVF-ANGRRVTVEDGNCT----VERPPVKQTCNRFACPE---WQAGPWSACSEKCGDAFQYRSVTCRSEKEGEEGKLLAADACPADEQEKFDTERTCNLGPCEGLTFVTGEWNLCT-RCNDTEETREVTCKDSQG-RAYPLEKCLVDNSTEIPTDTRSCATQPPCEYEWTVSEWSKCTTECGHGHKTRRVICAIHQNGGLEVVDEGHCQAEKPEGKTNCTNEEKCTGT-WYTSSWSEC 657
[Close]
BLAST of A disintegrin and metalloproteinase with thrombospondin motifs vs. Ensembl Fly
Match: AdamTS-A (gene:FBgn0286071 transcript:FBtr0339398)

HSP 1 Score: 246.128 bits (627), Expect = 2.732e-65
Identity = 260/1035 (25.12%), Postives = 435/1035 (42.03%), Query Frame = 1 
Query:  472 SRVFQRMKRETYPVVDSEIVEPNIIELLIVVTSNFVKRFKKDFRQYILSNVAIATKLLHDPTIKASITXXXXXXXXXXEDYERNNDLHDWSLLSQDRVVSRFCHWVRQKKQLWNYSWDSAILINDGVFSSNA-------IGIAHLRSMCNDNNCLAVVDRGFGTGFIIAHELAHQMNARHDFDNAEACSFFEKQYDNKTKYNTIMSTSLFFEYYPFIWSVCSQNVINSFLKSKYSFCLKQRNRHRNLYPHEQINEFFQKYSTGVDYDLNEQCSFAFGEKSEFCETDQNSRKKCSVLYCRL---KRYPICLRADAIIADGTECDVNQH-CINGKCLY-KNITIAPIDGGWSEYSEWSNCSRPCNGGVQFSYRTCDNPVPADGGRFCTGTKERIRSCNIEECSSFS-DPREESCGKYNLK----PYIPTNDEEFP------CNLVCITTNHSLKYDIS--LTDGTPCSPFRSDICVKGTCYKTGCDRIVGSKKAIDNCNICAGQNDTCFKKE---------SFFDGSKVAKVRMIRAFRIPPNVYNLFIKKVSQRMTPFTDEVYDDFELLLVVNRRTVIRRSETIE--PL----AGGQLRYSGSKNKVETISIKGKLNVGISIVIKVENTKTT----LNLPFISYHYFV-------KDIFVWKYLEVITHPCKDQCGGFIEISPACFKKRDNQRYVDHYCSKATKPEPKIIKCGAICGYRWQRATEHYINSTVN--KSCPIRCGT-GKVKIPFVC-QKINNQDDNNSLWETVEENLCFAVDLVDRPIEELNCVGQCNPLLWSYGKWEECPIECGTTFRYRNFIC-------KDNKGLEWQKEWCERHLGLPDNKETCLSFN---NCRNLTRWVTSPWSRCSNSCESELQKRMVYCFRSEKSDEILDEKFLKIHEQISDAFCDIHSPKPITERPCSLNSCYFWIXXXXXXXXXXXXLGFRIQSHECKKKFNKN-----HEMITVDDKFCLKQNLVKPLDVRMRCFLKKCAIESFWIEMEWSKCSVSCGEGLQYRSLKC 3366
            SR   R KR  Y  VD+++     +E+LI V ++  +   +D + YIL  ++I + +  D +I  SI I +V ++ L      N+  H     S + ++  FC ++ Q      Y  D+A+LI       +        +G+A L ++C+ ++C  V D G  T F +AHEL H +N  HD D+ +   +  +Q +NK  +  IMS+ +    +P+ WS CS++ ++ FL+     CL+        Y  E++         G  Y L+ QC  +FG    +C TD+    +C  L+C          C  ++   ADGT C  + H C  GKC+  K+     ++GGW  ++ ++ CS  C GGVQ S R C+ PVP +GG++CTG++++ RSCN  +C   S DPRE+ C   N +    P +  + +  P      C L C        + +   +TDGT C+    D CV G C   GCD  + S   +D C +C G+NDTC +              DG++  K  +    RIP    N+ I   +QR  P      D   ++L  +R   +   + ++  PL    AG  ++Y+GS + VE ++      +   +++++ +   +     +   +SY Y +        ++ ++++       C   C G     PAC       +    +C K+  P+     C   C           +N TV     C   CG  G  +  + C Q   N   +N +      ++ +     D    E     +C    W   +W  C   CGT  + R   C        D+      K      +G+  N E+C ++    N   ++ WV   W  C+  CE   + R V C                         C    PK +  R C    C+    S    CS +CG G + +   C + +  +        + VD+ +C+ + + +P   ++R   K C I   W   +W +C   C E  Q R ++C
Sbjct:  286 SRKLNRKKRH-YADVDNQVY---TLEVLIAVDNSMKQFHGEDLQPYILILMSIVSSIFADASIGNSIRILLVRLISLPNI---NDQTH-----SSNEMLKHFCQFINQS----GYERDTAMLITREPICGSVPGKICHMLGLAELGTVCSSSSCSIVQDTGLPTAFTMAHELGHILNMNHD-DDDKCMPYVTRQNNNKVLH--IMSSVMGIHMHPWSWSKCSRHFVSEFLEKTDKSCLETSVGAHIPYGTERL--------PGEIYSLDAQCQLSFGNDFGYCPTDE----ECKRLWCNRTSGNSNEQCASSNLPWADGTPCGSSGHWCQRGKCVSNKHGYGRQVNGGWGPWTPFTPCSLTCGGGVQESRRECNQPVPENGGKYCTGSRKKYRSCNTHQCPPGSMDPREQQCYAMNGRNMNIPGVNPDTKWVPKYEKDACKLFCRMDMKVTYFMLKSMVTDGTSCAVDSFDKCVNGICRPAGCDNELNSIAKLDKCGVCEGRNDTCHEVTGNLLVSNLLGLNDGNEPNKT-LYYVTRIPKGASNIII---TQRGYP------DQNFIVLTDDRDNELLNGKFLKTYPLKFVYAGVTMQYTGSSSVVEQVNTTYSWKLSRDLIVQIISLDVSPSKRQDTVLLSYSYTIDKPPDYEAEVEIYRWEMQAPSNCDSLCEGRSHRLPACISTTQGVKVAPQFCDKSAMPKIDDRACNTDC----------RLNLTVTSISECSAACGELGTREKTYACVQTFTNMQRSNIV------DMSYCKLKFDVAYHE-----ECREGCWVLSEWSTCSKSCGTGSQQREAHCYLHNSRVSDDLCNPRTKPHLNTLIGIC-NTESCPTYTKSPNALAVSNWVIGEWGECNEWCE---KTRSVSC------------------SHPYGIGCGSRKPKDV--RKC----CHIKYTSDWTDCSVQCGEGVKRKKQSCTRVYKPDVPGTRKRRVYVDESYCISRKVHRP---KLRTTTKSCRINCKWNASDWRRCPADCSEEYQTRDVRC 1227

HSP 2 Score: 124.02 bits (310), Expect = 8.241e-28
Identity = 162/651 (24.88%), Postives = 245/651 (37.63%), Query Frame = 1 
Query: 2881 RWVTSPWSRCSNSCESELQKRMVYCFRSEKSDEILDEKFLKIHEQISDAFCDIHSPKPITERPCSLN-SCYFWIXXXXXXXXXXXXLGFRIQSHECKKKFNKNHEMITVDDKFC-LKQNLVKPLDVRMRCFLKKCAIESFWIEMEWSKCSVSCGEGLQYRSLKCGYENENKTLTTWDNNEMCKNKMVP---VSIQICKVTPCP------------KWIYSEWSECEGTCEYGSQHRTVLCTDPISEQILPDSKCDIKNKFPNFQKCLLSKLCGHWIVGKWSQCSASCGLGVKTRTITCNYS-----NGSKS----IDHSVCKSVAPFE-EIHCQVKPCSTNAFW----WLVKPSECYEYNCQPGIMYAHVRCVNRKFQVLYDSKCSRIKHPSYYVGCLN---------TTC-------RRYFWTAESWDNIPCPDISCTMKIRNRDVYCVDDYGNIQKDAMCDQ-SDKPDTWRLCPSPQNCS-------NIPRSCKELKSRQSVSKDGEYSLAIDLNWAYFIYCADMNTEEPKEYLTLR-ELNYARTSKYVSTDVSSCIYEEE-MEFNQKCPTCKINENLWSITYYNKIRINLSDLSIDVMDDRFSATNGQSFIPFGTAKDCAGSTS-CPKGHFKINLRGTGFSVSMETRW 4659
            RW     S C + CE     R+  C  + +              +++  FCD  +   I +R C+ +      + S S   +A   LG R +++ C + F        VD  +C LK ++    + R  C          W+  EWS CS SCG G Q R   C   N   +      +++C  +  P     I IC    CP             W+  EW EC   CE   + R+V C+ P           D++            K C       W+ CS  CG GVK +  +C         G++     +D S C S      ++    K C  N  W    W   P++C E           VRC + +   + D  C   K PS    C N         + C       RR F        I CP      + R     C       ++ A+    S +P    +  S    S         PRSC +LK     +KDG Y L +     + IYC  MN+  P+EY+ +  + NY+   +Y +   +SC  E    E+         N+     T++ K+R+N++DL I   D +F+ + G +    G+A DC      CP+G F IN++ T FS+   T W
Sbjct:  905 RWEMQAPSNCDSLCEGR-SHRLPACISTTQG------------VKVAPQFCDKSAMPKIDDRACNTDCRLNLTVTSISECSAACGELGTREKTYACVQTFTNMQRSNIVDMSYCKLKFDVAYHEECREGC----------WVLSEWSTCSKSCGTGSQQREAHCYLHNSRVS------DDLCNPRTKPHLNTLIGICNTESCPTYTKSPNALAVSNWVIGEWGECNEWCE---KTRSVSCSHPYGIGCGSRKPKDVR------------KCCHIKYTSDWTDCSVQCGEGVKRKKQSCTRVYKPDVPGTRKRRVYVDESYCISRKVHRPKLRTTTKSCRINCKWNASDWRRCPADCSEE-----YQTRDVRCESFQGDGVEDKHCDAKKRPSKRRICNNCVRRQSRVISQCNCEGVEKRRDFCFNSHKGRIACP-----TRARVERHSCTPPPHCRRRSAIGSSISSRPRGTGVSSSRSLNSIGGSRNRGTPRSCADLKEMHGYNKDGNYQLEVRSRMVH-IYCHGMNSRTPQEYVNVDPQENYSIYYEYRTKQTNSCPPESRGHEY--------YNDQNSGRTHFRKLRLNITDLRIMDNDFKFADSRGLA-QKLGSAGDCYNRIGQCPQGDFSINMKDTDFSIRPGTVW 1491
[Close]
BLAST of A disintegrin and metalloproteinase with thrombospondin motifs vs. Ensembl Fly
Match: AdamTS-A (gene:FBgn0286071 transcript:FBtr0334629)

HSP 1 Score: 246.128 bits (627), Expect = 3.051e-65
Identity = 260/1035 (25.12%), Postives = 435/1035 (42.03%), Query Frame = 1 
Query:  472 SRVFQRMKRETYPVVDSEIVEPNIIELLIVVTSNFVKRFKKDFRQYILSNVAIATKLLHDPTIKASITXXXXXXXXXXEDYERNNDLHDWSLLSQDRVVSRFCHWVRQKKQLWNYSWDSAILINDGVFSSNA-------IGIAHLRSMCNDNNCLAVVDRGFGTGFIIAHELAHQMNARHDFDNAEACSFFEKQYDNKTKYNTIMSTSLFFEYYPFIWSVCSQNVINSFLKSKYSFCLKQRNRHRNLYPHEQINEFFQKYSTGVDYDLNEQCSFAFGEKSEFCETDQNSRKKCSVLYCRL---KRYPICLRADAIIADGTECDVNQH-CINGKCLY-KNITIAPIDGGWSEYSEWSNCSRPCNGGVQFSYRTCDNPVPADGGRFCTGTKERIRSCNIEECSSFS-DPREESCGKYNLK----PYIPTNDEEFP------CNLVCITTNHSLKYDIS--LTDGTPCSPFRSDICVKGTCYKTGCDRIVGSKKAIDNCNICAGQNDTCFKKE---------SFFDGSKVAKVRMIRAFRIPPNVYNLFIKKVSQRMTPFTDEVYDDFELLLVVNRRTVIRRSETIE--PL----AGGQLRYSGSKNKVETISIKGKLNVGISIVIKVENTKTT----LNLPFISYHYFV-------KDIFVWKYLEVITHPCKDQCGGFIEISPACFKKRDNQRYVDHYCSKATKPEPKIIKCGAICGYRWQRATEHYINSTVN--KSCPIRCGT-GKVKIPFVC-QKINNQDDNNSLWETVEENLCFAVDLVDRPIEELNCVGQCNPLLWSYGKWEECPIECGTTFRYRNFIC-------KDNKGLEWQKEWCERHLGLPDNKETCLSFN---NCRNLTRWVTSPWSRCSNSCESELQKRMVYCFRSEKSDEILDEKFLKIHEQISDAFCDIHSPKPITERPCSLNSCYFWIXXXXXXXXXXXXLGFRIQSHECKKKFNKN-----HEMITVDDKFCLKQNLVKPLDVRMRCFLKKCAIESFWIEMEWSKCSVSCGEGLQYRSLKC 3366
            SR   R KR  Y  VD+++     +E+LI V ++  +   +D + YIL  ++I + +  D +I  SI I +V ++ L      N+  H     S + ++  FC ++ Q      Y  D+A+LI       +        +G+A L ++C+ ++C  V D G  T F +AHEL H +N  HD D+ +   +  +Q +NK  +  IMS+ +    +P+ WS CS++ ++ FL+     CL+        Y  E++         G  Y L+ QC  +FG    +C TD+    +C  L+C          C  ++   ADGT C  + H C  GKC+  K+     ++GGW  ++ ++ CS  C GGVQ S R C+ PVP +GG++CTG++++ RSCN  +C   S DPRE+ C   N +    P +  + +  P      C L C        + +   +TDGT C+    D CV G C   GCD  + S   +D C +C G+NDTC +              DG++  K  +    RIP    N+ I   +QR  P      D   ++L  +R   +   + ++  PL    AG  ++Y+GS + VE ++      +   +++++ +   +     +   +SY Y +        ++ ++++       C   C G     PAC       +    +C K+  P+     C   C           +N TV     C   CG  G  +  + C Q   N   +N +      ++ +     D    E     +C    W   +W  C   CGT  + R   C        D+      K      +G+  N E+C ++    N   ++ WV   W  C+  CE   + R V C                         C    PK +  R C    C+    S    CS +CG G + +   C + +  +        + VD+ +C+ + + +P   ++R   K C I   W   +W +C   C E  Q R ++C
Sbjct:  334 SRKLNRKKRH-YADVDNQVY---TLEVLIAVDNSMKQFHGEDLQPYILILMSIVSSIFADASIGNSIRILLVRLISLPNI---NDQTH-----SSNEMLKHFCQFINQS----GYERDTAMLITREPICGSVPGKICHMLGLAELGTVCSSSSCSIVQDTGLPTAFTMAHELGHILNMNHD-DDDKCMPYVTRQNNNKVLH--IMSSVMGIHMHPWSWSKCSRHFVSEFLEKTDKSCLETSVGAHIPYGTERL--------PGEIYSLDAQCQLSFGNDFGYCPTDE----ECKRLWCNRTSGNSNEQCASSNLPWADGTPCGSSGHWCQRGKCVSNKHGYGRQVNGGWGPWTPFTPCSLTCGGGVQESRRECNQPVPENGGKYCTGSRKKYRSCNTHQCPPGSMDPREQQCYAMNGRNMNIPGVNPDTKWVPKYEKDACKLFCRMDMKVTYFMLKSMVTDGTSCAVDSFDKCVNGICRPAGCDNELNSIAKLDKCGVCEGRNDTCHEVTGNLLVSNLLGLNDGNEPNKT-LYYVTRIPKGASNIII---TQRGYP------DQNFIVLTDDRDNELLNGKFLKTYPLKFVYAGVTMQYTGSSSVVEQVNTTYSWKLSRDLIVQIISLDVSPSKRQDTVLLSYSYTIDKPPDYEAEVEIYRWEMQAPSNCDSLCEGRSHRLPACISTTQGVKVAPQFCDKSAMPKIDDRACNTDC----------RLNLTVTSISECSAACGELGTREKTYACVQTFTNMQRSNIV------DMSYCKLKFDVAYHE-----ECREGCWVLSEWSTCSKSCGTGSQQREAHCYLHNSRVSDDLCNPRTKPHLNTLIGIC-NTESCPTYTKSPNALAVSNWVIGEWGECNEWCE---KTRSVSC------------------SHPYGIGCGSRKPKDV--RKC----CHIKYTSDWTDCSVQCGEGVKRKKQSCTRVYKPDVPGTRKRRVYVDESYCISRKVHRP---KLRTTTKSCRINCKWNASDWRRCPADCSEEYQTRDVRC 1275

HSP 2 Score: 123.635 bits (309), Expect = 9.197e-28
Identity = 162/653 (24.81%), Postives = 246/653 (37.67%), Query Frame = 1 
Query: 2875 LTRWVTSPWSRCSNSCESELQKRMVYCFRSEKSDEILDEKFLKIHEQISDAFCDIHSPKPITERPCSLN-SCYFWIXXXXXXXXXXXXLGFRIQSHECKKKFNKNHEMITVDDKFC-LKQNLVKPLDVRMRCFLKKCAIESFWIEMEWSKCSVSCGEGLQYRSLKCGYENENKTLTTWDNNEMCKNKMVP---VSIQICKVTPCP------------KWIYSEWSECEGTCEYGSQHRTVLCTDPISEQILPDSKCDIKNKFPNFQKCLLSKLCGHWIVGKWSQCSASCGLGVKTRTITCNYS-----NGSKS----IDHSVCKSVAPFE-EIHCQVKPCSTNAFW----WLVKPSECYEYNCQPGIMYAHVRCVNRKFQVLYDSKCSRIKHPSYYVGCLN---------TTC-------RRYFWTAESWDNIPCPDISCTMKIRNRDVYCVDDYGNIQKDAMCDQ-SDKPDTWRLCPSPQNCS-------NIPRSCKELKSRQSVSKDGEYSLAIDLNWAYFIYCADMNTEEPKEYLTLR-ELNYARTSKYVSTDVSSCIYEEE-MEFNQKCPTCKINENLWSITYYNKIRINLSDLSIDVMDDRFSATNGQSFIPFGTAKDCAGSTS-CPKGHFKINLRGTGFSVSMETRW 4659
            + RW     S C + CE     R+  C  + +              +++  FCD  +   I +R C+ +      + S S   +A   LG R +++ C + F        VD  +C LK ++    + R  C          W+  EWS CS SCG G Q R   C   N   +      +++C  +  P     I IC    CP             W+  EW EC   CE   + R+V C+ P           D++            K C       W+ CS  CG GVK +  +C         G++     +D S C S      ++    K C  N  W    W   P++C E           VRC + +   + D  C   K PS    C N         + C       RR F        I CP      + R     C       ++ A+    S +P    +  S    S         PRSC +LK     +KDG Y L +     + IYC  MN+  P+EY+ +  + NY+   +Y +   +SC  E    E+         N+     T++ K+R+N++DL I   D +F+ + G +    G+A DC      CP+G F IN++ T FS+   T W
Sbjct:  951 IYRWEMQAPSNCDSLCEGR-SHRLPACISTTQG------------VKVAPQFCDKSAMPKIDDRACNTDCRLNLTVTSISECSAACGELGTREKTYACVQTFTNMQRSNIVDMSYCKLKFDVAYHEECREGC----------WVLSEWSTCSKSCGTGSQQREAHCYLHNSRVS------DDLCNPRTKPHLNTLIGICNTESCPTYTKSPNALAVSNWVIGEWGECNEWCE---KTRSVSCSHPYGIGCGSRKPKDVR------------KCCHIKYTSDWTDCSVQCGEGVKRKKQSCTRVYKPDVPGTRKRRVYVDESYCISRKVHRPKLRTTTKSCRINCKWNASDWRRCPADCSEE-----YQTRDVRCESFQGDGVEDKHCDAKKRPSKRRICNNCVRRQSRVISQCNCEGVEKRRDFCFNSHKGRIACP-----TRARVERHSCTPPPHCRRRSAIGSSISSRPRGTGVSSSRSLNSIGGSRNRGTPRSCADLKEMHGYNKDGNYQLEVRSRMVH-IYCHGMNSRTPQEYVNVDPQENYSIYYEYRTKQTNSCPPESRGHEY--------YNDQNSGRTHFRKLRLNITDLRIMDNDFKFADSRGLA-QKLGSAGDCYNRIGQCPQGDFSINMKDTDFSIRPGTVW 1539
[Close]
BLAST of A disintegrin and metalloproteinase with thrombospondin motifs vs. Ensembl Fly
Match: AdamTS-A (gene:FBgn0286071 transcript:FBtr0083160)

HSP 1 Score: 246.128 bits (627), Expect = 3.548e-65
Identity = 260/1035 (25.12%), Postives = 435/1035 (42.03%), Query Frame = 1 
Query:  472 SRVFQRMKRETYPVVDSEIVEPNIIELLIVVTSNFVKRFKKDFRQYILSNVAIATKLLHDPTIKASITXXXXXXXXXXEDYERNNDLHDWSLLSQDRVVSRFCHWVRQKKQLWNYSWDSAILINDGVFSSNA-------IGIAHLRSMCNDNNCLAVVDRGFGTGFIIAHELAHQMNARHDFDNAEACSFFEKQYDNKTKYNTIMSTSLFFEYYPFIWSVCSQNVINSFLKSKYSFCLKQRNRHRNLYPHEQINEFFQKYSTGVDYDLNEQCSFAFGEKSEFCETDQNSRKKCSVLYCRL---KRYPICLRADAIIADGTECDVNQH-CINGKCLY-KNITIAPIDGGWSEYSEWSNCSRPCNGGVQFSYRTCDNPVPADGGRFCTGTKERIRSCNIEECSSFS-DPREESCGKYNLK----PYIPTNDEEFP------CNLVCITTNHSLKYDIS--LTDGTPCSPFRSDICVKGTCYKTGCDRIVGSKKAIDNCNICAGQNDTCFKKE---------SFFDGSKVAKVRMIRAFRIPPNVYNLFIKKVSQRMTPFTDEVYDDFELLLVVNRRTVIRRSETIE--PL----AGGQLRYSGSKNKVETISIKGKLNVGISIVIKVENTKTT----LNLPFISYHYFV-------KDIFVWKYLEVITHPCKDQCGGFIEISPACFKKRDNQRYVDHYCSKATKPEPKIIKCGAICGYRWQRATEHYINSTVN--KSCPIRCGT-GKVKIPFVC-QKINNQDDNNSLWETVEENLCFAVDLVDRPIEELNCVGQCNPLLWSYGKWEECPIECGTTFRYRNFIC-------KDNKGLEWQKEWCERHLGLPDNKETCLSFN---NCRNLTRWVTSPWSRCSNSCESELQKRMVYCFRSEKSDEILDEKFLKIHEQISDAFCDIHSPKPITERPCSLNSCYFWIXXXXXXXXXXXXLGFRIQSHECKKKFNKN-----HEMITVDDKFCLKQNLVKPLDVRMRCFLKKCAIESFWIEMEWSKCSVSCGEGLQYRSLKC 3366
            SR   R KR  Y  VD+++     +E+LI V ++  +   +D + YIL  ++I + +  D +I  SI I +V ++ L      N+  H     S + ++  FC ++ Q      Y  D+A+LI       +        +G+A L ++C+ ++C  V D G  T F +AHEL H +N  HD D+ +   +  +Q +NK  +  IMS+ +    +P+ WS CS++ ++ FL+     CL+        Y  E++         G  Y L+ QC  +FG    +C TD+    +C  L+C          C  ++   ADGT C  + H C  GKC+  K+     ++GGW  ++ ++ CS  C GGVQ S R C+ PVP +GG++CTG++++ RSCN  +C   S DPRE+ C   N +    P +  + +  P      C L C        + +   +TDGT C+    D CV G C   GCD  + S   +D C +C G+NDTC +              DG++  K  +    RIP    N+ I   +QR  P      D   ++L  +R   +   + ++  PL    AG  ++Y+GS + VE ++      +   +++++ +   +     +   +SY Y +        ++ ++++       C   C G     PAC       +    +C K+  P+     C   C           +N TV     C   CG  G  +  + C Q   N   +N +      ++ +     D    E     +C    W   +W  C   CGT  + R   C        D+      K      +G+  N E+C ++    N   ++ WV   W  C+  CE   + R V C                         C    PK +  R C    C+    S    CS +CG G + +   C + +  +        + VD+ +C+ + + +P   ++R   K C I   W   +W +C   C E  Q R ++C
Sbjct:  437 SRKLNRKKRH-YADVDNQVY---TLEVLIAVDNSMKQFHGEDLQPYILILMSIVSSIFADASIGNSIRILLVRLISLPN---INDQTH-----SSNEMLKHFCQFINQS----GYERDTAMLITREPICGSVPGKICHMLGLAELGTVCSSSSCSIVQDTGLPTAFTMAHELGHILNMNHD-DDDKCMPYVTRQNNNKVLH--IMSSVMGIHMHPWSWSKCSRHFVSEFLEKTDKSCLETSVGAHIPYGTERL--------PGEIYSLDAQCQLSFGNDFGYCPTDE----ECKRLWCNRTSGNSNEQCASSNLPWADGTPCGSSGHWCQRGKCVSNKHGYGRQVNGGWGPWTPFTPCSLTCGGGVQESRRECNQPVPENGGKYCTGSRKKYRSCNTHQCPPGSMDPREQQCYAMNGRNMNIPGVNPDTKWVPKYEKDACKLFCRMDMKVTYFMLKSMVTDGTSCAVDSFDKCVNGICRPAGCDNELNSIAKLDKCGVCEGRNDTCHEVTGNLLVSNLLGLNDGNEPNKT-LYYVTRIPKGASNIII---TQRGYP------DQNFIVLTDDRDNELLNGKFLKTYPLKFVYAGVTMQYTGSSSVVEQVNTTYSWKLSRDLIVQIISLDVSPSKRQDTVLLSYSYTIDKPPDYEAEVEIYRWEMQAPSNCDSLCEGRSHRLPACISTTQGVKVAPQFCDKSAMPKIDDRACNTDC----------RLNLTVTSISECSAACGELGTREKTYACVQTFTNMQRSNIV------DMSYCKLKFDVAYHE-----ECREGCWVLSEWSTCSKSCGTGSQQREAHCYLHNSRVSDDLCNPRTKPHLNTLIGIC-NTESCPTYTKSPNALAVSNWVIGEWGECNEWCE---KTRSVSC------------------SHPYGIGCGSRKPKDV--RKC----CHIKYTSDWTDCSVQCGEGVKRKKQSCTRVYKPDVPGTRKRRVYVDESYCISRKVHRP---KLRTTTKSCRINCKWNASDWRRCPADCSEEYQTRDVRC 1378

HSP 2 Score: 123.25 bits (308), Expect = 1.193e-27
Identity = 162/651 (24.88%), Postives = 245/651 (37.63%), Query Frame = 1 
Query: 2881 RWVTSPWSRCSNSCESELQKRMVYCFRSEKSDEILDEKFLKIHEQISDAFCDIHSPKPITERPCSLN-SCYFWIXXXXXXXXXXXXLGFRIQSHECKKKFNKNHEMITVDDKFC-LKQNLVKPLDVRMRCFLKKCAIESFWIEMEWSKCSVSCGEGLQYRSLKCGYENENKTLTTWDNNEMCKNKMVP---VSIQICKVTPCP------------KWIYSEWSECEGTCEYGSQHRTVLCTDPISEQILPDSKCDIKNKFPNFQKCLLSKLCGHWIVGKWSQCSASCGLGVKTRTITCNYS-----NGSKS----IDHSVCKSVAPFE-EIHCQVKPCSTNAFW----WLVKPSECYEYNCQPGIMYAHVRCVNRKFQVLYDSKCSRIKHPSYYVGCLN---------TTC-------RRYFWTAESWDNIPCPDISCTMKIRNRDVYCVDDYGNIQKDAMCDQ-SDKPDTWRLCPSPQNCS-------NIPRSCKELKSRQSVSKDGEYSLAIDLNWAYFIYCADMNTEEPKEYLTLR-ELNYARTSKYVSTDVSSCIYEEE-MEFNQKCPTCKINENLWSITYYNKIRINLSDLSIDVMDDRFSATNGQSFIPFGTAKDCAGSTS-CPKGHFKINLRGTGFSVSMETRW 4659
            RW     S C + CE     R+  C  + +              +++  FCD  +   I +R C+ +      + S S   +A   LG R +++ C + F        VD  +C LK ++    + R  C          W+  EWS CS SCG G Q R   C   N   +      +++C  +  P     I IC    CP             W+  EW EC   CE   + R+V C+ P           D++            K C       W+ CS  CG GVK +  +C         G++     +D S C S      ++    K C  N  W    W   P++C E           VRC + +   + D  C   K PS    C N         + C       RR F        I CP      + R     C       ++ A+    S +P    +  S    S         PRSC +LK     +KDG Y L +     + IYC  MN+  P+EY+ +  + NY+   +Y +   +SC  E    E+         N+     T++ K+R+N++DL I   D +F+ + G +    G+A DC      CP+G F IN++ T FS+   T W
Sbjct: 1056 RWEMQAPSNCDSLCEGR-SHRLPACISTTQG------------VKVAPQFCDKSAMPKIDDRACNTDCRLNLTVTSISECSAACGELGTREKTYACVQTFTNMQRSNIVDMSYCKLKFDVAYHEECREGC----------WVLSEWSTCSKSCGTGSQQREAHCYLHNSRVS------DDLCNPRTKPHLNTLIGICNTESCPTYTKSPNALAVSNWVIGEWGECNEWCE---KTRSVSCSHPYGIGCGSRKPKDVR------------KCCHIKYTSDWTDCSVQCGEGVKRKKQSCTRVYKPDVPGTRKRRVYVDESYCISRKVHRPKLRTTTKSCRINCKWNASDWRRCPADCSEE-----YQTRDVRCESFQGDGVEDKHCDAKKRPSKRRICNNCVRRQSRVISQCNCEGVEKRRDFCFNSHKGRIACP-----TRARVERHSCTPPPHCRRRSAIGSSISSRPRGTGVSSSRSLNSIGGSRNRGTPRSCADLKEMHGYNKDGNYQLEVRSRMVH-IYCHGMNSRTPQEYVNVDPQENYSIYYEYRTKQTNSCPPESRGHEY--------YNDQNSGRTHFRKLRLNITDLRIMDNDFKFADSRGLA-QKLGSAGDCYNRIGQCPQGDFSINMKDTDFSIRPGTVW 1642
[Close]
BLAST of A disintegrin and metalloproteinase with thrombospondin motifs vs. Ensembl Fly
Match: AdamTS-B (gene:FBgn0029791 transcript:FBtr0301083)

HSP 1 Score: 196.438 bits (498), Expect = 1.788e-50
Identity = 172/633 (27.17%), Postives = 277/633 (43.76%), Query Frame = 1 
Query:  544 IELLIVVTSNFVKRFKKDFRQYILSNVAIATKLLHDPTIKASITXXXXXXXXXXEDYERNNDLHDWSLLSQDRVVSRFCHW---VRQKKQLWNYSWDSAILINDGVFSSN---AIGIAHLRSMCN-DNNCLAVVDRGFGTGFIIAHELAHQMNARHDFDNAEACSFFEKQYDNKTKYNTIMSTSLFFEYYPFIWSVCSQNVINSFLKSKYSFCLKQRNRHRNLYPHEQINEF-FQKYSTGVDYDLNEQCSFAFGEKSEFCETDQNSRKK--CSVLYCRLKRYPICLRADAIIADGTECDVNQHCINGKCLYKNITIAPIDGGWSEYSEWSNCSRPCNGGVQFSYRTCDNPVPADGGRFCTGTKERIRSCNIEECSSFSDP--REESCGKYNLKPY-------IPTNDEEFPCNLVCITTNHSL--KYDISLTDGTPCSPFRSDICVKGTCYKTGCDRIVGSKKAIDNCNICAGQNDTCFK-KESFFDGSKVAKVRMIRAFRIPPNVYNLFIKKVSQR---MTPFTDEVYDDFELLLVVNRRTVIRRSETIEPLAGGQLRYSGSKNKVETISIKGKLNVGISIVIKVENTKTTLNL----PFISYHYFVKDIFVWKYLEVITHPCKDQCGGFIE 2355
            +E LIV  +  +  F +D   Y+L+ + + + L  DP+I  SI I VV I+ LDE+    + L      +  + + RFC W   + +  +   +  D AILI      +N    +G+A++  MC    +C    D G      I HEL H     HD      C      +        IM+ +   +     WS CS+  I  FL      CL          P   ++E+ +     G+ Y+   QC   F   ++  E    S     CS L+C++     C+      A GT C  N+ C NGKC+ +   +A ++GGW ++SEWS CSR C GGV    R CDNPVPA+GG FC G ++R + C    C +  +P  R + C +++   Y       +P  D+  PC L C   + ++   +  ++ DGTPC+   +++C+ G C K GCD IV S+   D C +C G  D C   +E++ D         +    IP    ++ I++++     +   T +  D F L    N  ++I      E +AG +  Y    ++ ETI+I   +   IS+   V   ++   +       + +      F W+        C   CGG ++
Sbjct:  315 VETLIVADAT-MSAFHRDLNGYLLTIMNMVSALYKDPSIGNSIEIVVVRIIQLDEE---ESQLQLNLTQNAQKNLDRFCSWQHKLNKGSEKDPHHHDVAILITRKNICANNCMTLGLANVGGMCKPKQSCSVNEDNGIMLSHTITHELGHNFGMFHDTAKI-GC------HPRVGPIVHIMTPTFGADTLQVCWSNCSRKYITHFLDQGLGECLDD--------PPTPLDEYNYTGELPGMRYNARGQCRLQFNLTTD-SEVGACSAPHEFCSTLWCKVNGE--CVTHMRPTAPGTLCGRNKWCQNGKCVRRE-ELAAVNGGWGDWSEWSECSRSCGGGVSTQQRECDNPVPANGGVFCIGERKRYKICRKRPCPA-EEPSFRAQQCARFDNVSYQGATYKWLPFFDKNNPCKLFCSDVDDTIIANWGATVLDGTPCTLGTNNMCIDGICKKVGCDWIVDSEVQDDRCGVCGGSGDQCQPVRETYTDPFAAKDGAYVEIVTIPARARHILIRELANSPHFLAIATGDGGDRFYL----NGDSLISMPGEFE-IAGAESLYD-RVDEQETITIPQPIQHSISLYAIVRGNESNAGIFYEFTLPALNVTAGRQFQWRLSNWTA--CSASCGGGVQ 915
[Close]
BLAST of A disintegrin and metalloproteinase with thrombospondin motifs vs. Ensembl Fly
Match: AdamTS-B (gene:FBgn0029791 transcript:FBtr0301084)

HSP 1 Score: 162.155 bits (409), Expect = 3.042e-40
Identity = 131/450 (29.11%), Postives = 205/450 (45.56%), Query Frame = 1 
Query:  544 IELLIVVTSNFVKRFKKDFRQYILSNVAIATKLLHDPTIKASITXXXXXXXXXXEDYERNNDLHDWSLLSQDRVVSRFCHW---VRQKKQLWNYSWDSAILINDGVFSSN---AIGIAHLRSMCN-DNNCLAVVDRGFGTGFIIAHELAHQMNARHDFDNAEACSFFEKQYDNKTKYNTIMSTSLFFEYYPFIWSVCSQNVINSFLKSKYSFCLKQRNRHRNLYPHEQINEF-FQKYSTGVDYDLNEQCSFAFGEKSEFCETDQNSRKK--CSVLYCRLKRYPICLRADAIIADGTECDVNQHCINGKCLYKNITIAPIDGGWSEYSEWSNCSRPCNGGVQFSYRTCDNPVPADGGRFCTGTKERIRSCNIEECSSFSDP--REESCGKYNLKPY-------IPTNDEEFPCNLVCITTNHSL--KYDISLTDGTPCSPFRSDICVKGTC 1830
            +E LIV  +  +  F +D   Y+L+ + + + L  DP+I  SI I VV I+ LDE+    + L      +  + + RFC W   + +  +   +  D AILI      +N    +G+A++  MC    +C    D G      I HEL H     HD      C      +        IM+ +   +     WS CS+  I  FL      CL          P   ++E+ +     G+ Y+   QC   F   ++  E    S     CS L+C++     C+      A GT C  N+ C NGKC+ +   +A ++GGW ++SEWS CSR C GGV    R CDNPVPA+GG FC G ++R + C    C +  +P  R + C +++   Y       +P  D+  PC L C   + ++   +  ++ DGTPC+   +++C+ G C
Sbjct:  315 VETLIVADAT-MSAFHRDLNGYLLTIMNMVSALYKDPSIGNSIEIVVVRIIQLDEE---ESQLQLNLTQNAQKNLDRFCSWQHKLNKGSEKDPHHHDVAILITRKNICANNCMTLGLANVGGMCKPKQSCSVNEDNGIMLSHTITHELGHNFGMFHDTAKI-GC------HPRVGPIVHIMTPTFGADTLQVCWSNCSRKYITHFLDQGLGECLDD--------PPTPLDEYNYTGELPGMRYNARGQCRLQFNLTTD-SEVGACSAPHEFCSTLWCKVNGE--CVTHMRPTAPGTLCGRNKWCQNGKCVRRE-ELAAVNGGWGDWSEWSECSRSCGGGVSTQQRECDNPVPANGGVFCIGERKRYKICRKRPCPA-EEPSFRAQQCARFDNVSYQGATYKWLPFFDKNNPCKLFCSDVDDTIIANWGATVLDGTPCTLGTNNMCIDGIC 740
[Close]
BLAST of A disintegrin and metalloproteinase with thrombospondin motifs vs. Ensembl Zebrafish
Match: adamts9 (ADAM metallopeptidase with thrombospondin type 1 motif, 9 [Source:ZFIN;Acc:ZDB-GENE-070814-6])

HSP 1 Score: 358.221 bits (918), Expect = 6.500e-101
Identity = 347/1407 (24.66%), Postives = 566/1407 (40.23%), Query Frame = 1 
Query:  157 KERVQSG-EHLSMTLFCQSLISVLLNFNPFIYLEYHNSDGVFQWDNKLWFIKPNT--------KTKFNSKFLKTEMNFLPHKIYFTALNLNKPLFSCKLLKNNGYRNIP---------QESHFSRVFQRMKRETYPVVDSEIVEPNIIELLIVVTSNFVKRFKKDFRQYILSNVAIATKLLHDPTIKASITXXXXXXXXXXEDYERNNDLHDWSL-LSQDRVVSRFCHWVRQKKQLWN---YSWDSAILINDGVF-----SSNAIGIAHLRSMCND-NNCLAVVDRGFGTGFIIAHELAHQMNARHDFDNAEACSFFEKQYDNKTKYNTIMSTSLFFEYYPFIWSVCSQNVINSFLKSKYSFCLKQRNRHRNLYPHEQINEFFQKYSTGVDYDLNEQCSFAFGEKSEFCETDQNSRKKCSVLYCR----LKRYPICLRADAIIADGTECDVNQHCINGKCLYKNITIAPIDGGWSEYSEWSNCSRPCNGGVQFSYRTCDNPVPADGGRFCTGTKERIRSCNIEECS-SFSDPREESCGKYNLKPY----IPTNDEEFP----------CNLVCITTNHSLKYDI--SLTDGTPCSPFRSDICVKGTCYKTGCDRIVGSKKAIDNCNICAGQNDTCFKKESFFDGSKVAKVRMIRAFRIPPNVYNLFIKKVSQRMTPFTDEVYDDFELLLVVNRRTVIRRSETIEPLAGGQLR-------YSGSKNKVETISIKGKLNVGISI-VIKVEN-----TKTTLNLPFIS--YHYFVKDIFVWKYLEVITHPCKDQCGGFIEISPACFKKRDNQRYVDHYCSKATKPEPKIIKCGAICGYRWQRATEHYINSTVNKSCPIRCGTGKVKIPFVCQKINNQDDNNSLWETVEENLCFAVDLVDRPIEELNCVGQCNPLLWSYGKWEECPIECGTTFRYRNFICKDNKGLEWQKEWCERHLGLPDNKETCLSFNNCRNL--TRWVTSPWSRCSNSCESELQKRMVYCFRSEKSDEILDEKFLKIHEQISDAFCDIHSPKPITERPCSLNSCYFWIXXXXXXXXXXXXLGFRIQSHECKKKFNKNHEMITVDDKFCLKQNLVKPLDVRMRCFLKKCAI----------------ESFWIEMEWSKCSVSCGEGLQYRSLKCGYENENKTLTTWDNNEMCKNKMVPVSIQICKVTPCPKWIYSEWSECEGTCEYGSQHRTVLCTDPISEQILPDSKCDIKNKFPNFQKCLL----------------------SKLCG-------------HWIVGKWSQCSASCGLGVKTRTITCNYSNGSKSIDHSVCKSVAPFEEIHCQVKPCSTNAFWWLVKPSECYEYNCQPGIMYAHVRCVNRKFQVLYDSKCSRIKHPSYYVGCLNTTCR-RYFWTAESW 4023
            K  V +G EH ++   C  L+    +     ++E  +S     ++ +   IKP+         KT  +S   +T  +  P++ +   L    P      L+    R  P          ES  S+  +R KR         +  P  +E+++V  S  V+    + + YIL+ ++I + +  DP+I   I I +V +V++       N+L   ++  +    +  FC W + +    +      D+AILI            + +G+A L ++C+   +C    D G  T F IAHEL H  N  HD  N       + + D       +M+ +L +   P++WS CS+  I  FL + Y  CL      R     +Q+         G  Y +N+QC   FG  ++ C        +C  L+C     ++R   C       ADGT+C   +HC +G C++K     P++G W  +S +  CSR C GG++ + R C+ PVP +GG++C G + + RSCN E CS    D REE C  ++ + +    +P N    P          C L C     +  Y +   +TDGT C P  +DICV+G C + GCD ++ SK   D C +C G N +C      F+   +         RIP    N+ +++ S     ++ +  DD  L L  +R   +   + +  +   ++R       YSGS + VE I+   ++   I I V+ V N      + + N+P      H+F      W+   ++       C G  +    C ++ D     D  C    KP      C   C   W  A +          C   CG G   +   C K +  D      + V+E  C +     +P ++  C G CNP  W Y  W EC   CG   R RN IC  +          ER      N +  L+   C      +W T  WS C  +C    + R  +C   E              E++   FCD  S KP + + C    C  W     G+C+  CG G+++++ +C      +     +DD  C      +P D +  C L +C +                ++ W    W++CS +CG+G + R + C  +              C +   P + ++C +  C +W   EW+ C  +C  G+  R V+C + IS+Q++  S+CD+ +K    Q+C +                      + L G              W  G W  CS++C  G + R + C   NG  +I  S  +S+ P E+  C+   C     W+    SEC + +C  GI    V C     +   D  C  +  P     C   +C     W+ + W
Sbjct:  112 KGHVNAGQEHTAVISLCSGLLGTFRSPEGEFFVEPLHSYNSEHYEEE--HIKPHVVYRKDASKKTVDDSAACETSGHTEPNRRHRNRLKRKSPSSMLSDLETLNSRLFPFSENKHNSANESSDSKPHRRSKRF--------LSYPRFVEVMVVADSKMVEHHGSNLQHYILTLMSIVSSIYKDPSIGNLINIVIVKLVII------KNELDGPTISFNAQATLKNFCIWQQSQNHPDDNHPSHHDTAILITRQDICRARDKCDTLGLAELGTVCDPYRSCSINEDNGLSTAFTIAHELGHVFNMPHDDSN-------KCKEDGVKNQQHVMAPTLNYYTNPWMWSKCSRKYITEFLDTGYGECLLDEPVSRPYSLSQQL--------PGQIYSVNKQCELIFGPGTQVCPY----MTQCRRLWCTSPDGVQRG--CRTQHMPWADGTDCAPGKHCKHGLCIHKEHEYVPVEGAWGVWSPFGTCSRTCGGGIKIAVRECNRPVPRNGGKYCVGRRMKFRSCNSEPCSKQKKDFREEQCASFDGRHFNINGLPPNVRWVPKYSGILMKDRCKLFCRVAGSTAYYQLRDRVTDGTQCGPDTNDICVQGLCRQAGCDHVLNSKARRDKCGVCGGDNSSCKPVAGTFN---IVHYGYNVVVRIPSGATNIDVRQHS-----YSGKAEDDNYLALSNSRGEYLLNGDFVVSMFKREVRVGNAVIEYSGSDHVVERINCTDRIEEEIIIQVLSVGNLYNPDVRYSYNIPIEDKPQHFFWDAYGPWQDCSLL-------CQGERKKKILCNRESDRVVVSDQRCHGLPKPAAITESCNTDCELGWHIARK--------SECTAACGVGYRSLDIYCTKQSRLDGKT---QKVDERYCSS---QHKPNDKEVCHGDCNPGGWEYSSWSECSRSCGGGTRRRNAICGKSD---------ERDDDSKCNPQEKLTAQPCNEFLCPQWKTGDWSECLVTCGKGYKHRQTWCQFGE--------------ERLDVRFCD--SSKPESVQACQQQECASWQVGPWGQCTTTCGPGYQMRAVKCVVGSYGS----VMDDTEC--NAATRPTDTQ-DCELSQCPVTHPVAPEPKVMPHPGHKTQWRFGSWTQCSATCGKGTRMRYVSCRDQQGGVA-----EESACAHLPKPPASEVCSIVACGQWKVLEWTACSVSCGQGTTTRQVVCMN-ISDQVVELSECDLDDKPAAEQECAMPQCPSRSSDHGGFSPNPDFRKKTALPGRTDRNRAGRLQAQQWRTGPWGACSSTCAGGFQRRVVVCQDENGYPAI--SCDESIQPIEQRSCESGSCPQ---WFYGSWSECSK-SCGGGIKTRLVACQRPNGERFNDLSCEILDKPPDREQCNTQSCSINPHWSTDQW 1408

HSP 2 Score: 120.939 bits (302), Expect = 9.110e-27
Identity = 118/445 (26.52%), Postives = 187/445 (42.02%), Query Frame = 1 
Query: 2893 SPWSRCSNSCESELQKRMVYCFRSEKSDEILDEKFLKIHEQISDAFC-DIHSPKPITERPCSLNSCYFWIXXXXXXXXXXXXLGFRIQSHECKKKFNKNHEMITVDDKFCLKQNLVKPLDVRMRCFLKKCAIESFWIEMEWSKCSVSCGEGLQYRSLKCGYENENKTLTTWDNNEMCKNKMVPVSIQICKVTPCPKWIYSEWSECEGTCEYGSQHRTVLCTDPISEQILPDSKCDIKNKFPNFQKCLLSKLCGHWIVGKWSQCSASCGLGVKTRTITCNYSNGSKSIDHSVCKSVA-PFEEIHCQVKPCSTN----------------AFWWLVKPSECYEYNCQPGIMYAHVRCVNRKFQVLYDSKCSRIKHPSYYVGCLNTTCRRYFWTAESWDNIPCPDISCTMKIRNRDVYCVDDYGNIQKDAMCDQSDKPDTWRLCPSPQ 4173
             PW  CS  C+ E +K+++ C R  +SD ++          +SD  C  +  P  ITE  C+ +    W  ++  +C+A CG+G+R     C K+   + +   VD+++C  Q+  KP D  + C          W    WS+CS SCG G + R+  CG  +E       D++  C N    ++ Q C    CP+W   +WSEC  TC  G +HR   C     E+ L    CD  +K  + Q C   + C  W VG W QC+ +CG G + R + C   +    +D + C +   P +   C++  C                     W     ++C    C  G    +V C +++  V  +S C+ +  P     C    C +  W    W       +SC      R V C++    + + + CD  DKP   + C  PQ
Sbjct:  842 GPWQDCSLLCQGERKKKIL-CNR--ESDRVV----------VSDQRCHGLPKPAAITES-CNTDCELGWHIARKSECTAACGVGYRSLDIYCTKQSRLDGKTQKVDERYCSSQH--KPNDKEV-CHGD--CNPGGWEYSSWSECSRSCGGGTRRRNAICGKSDER------DDDSKC-NPQEKLTAQPCNEFLCPQWKTGDWSECLVTCGKGYKHRQTWCQ--FGEERLDVRFCD-SSKPESVQACQQQE-CASWQVGPWGQCTTTCGPGYQMRAVKCVVGSYGSVMDDTECNAATRPTDTQDCELSQCPVTHPVAPEPKVMPHPGHKTQWRFGSWTQC-SATCGKGTRMRYVSCRDQQGGVAEESACAHLPKPPASEVCSIVACGQ--WKVLEWTAC---SVSCGQGTTTRQVVCMNISDQVVELSECDLDDKPAAEQECAMPQ 1250

HSP 3 Score: 103.219 bits (256), Expect = 2.004e-21
Identity = 85/332 (25.60%), Postives = 127/332 (38.25%), Query Frame = 1 
Query: 2701 WSYGKWEECPIECGTTFRYRNFICKDNKGLEWQKEWCERHLGLPDNKETCLSFNNCRNLTRWVTSPWSRCSNSCESELQKRMVYCFRSEKSDEILDEKFLKIHEQISDAFCDIHSPKPITERPCSLNSCYFWIXXXXXXXXXXXXLGFRIQSHECKKKFNKNHEMITVDDKFCLKQNLVKPLDVRMRCFLKKCAIESFWIEMEWSKCSVSCGEGLQYRSLKCGYENENKTLTTWDNNEMCKNKMVPVSIQICKVTPCPKWIYSEWSECEGTCEYGSQHRTVLCTDPISEQILPDSKCDIKNKFPNFQKCLLS--KLCGHWIVGKWSQCSASC 3690
            W +G W +C   CG   R R   C+D +G   ++  C  HL  P   E C S   C    +W    W+ CS SC      R V C         + ++ +++ E      CD+   KP  E+ C++  C                              + +H   + +  F  K  L    D      L+       W    W  CS +C  G Q R + C  EN    ++       C   + P+  + C+   CP+W Y  WSEC  +C  G + R V C  P  E+   D  C+I +K P+ ++C      +  HW   +WS C ASC
Sbjct: 1142 WRFGSWTQCSATCGKGTRMRYVSCRDQQGGVAEESACA-HLPKPPASEVC-SIVAC---GQWKVLEWTACSVSCGQGTTTRQVVCMN-------ISDQVVELSE------CDLDD-KPAAEQECAMPQC---------------------------PSRSSDHGGFSPNPDFRKKTALPGRTDRNRAGRLQA----QQWRTGPWGACSSTCAGGFQRRVVVCQDENGYPAIS-------CDESIQPIEQRSCESGSCPQWFYGSWSECSKSCGGGIKTRLVACQRPNGER-FNDLSCEILDKPPDREQCNTQSCSINPHWSTDQWSLCFASC 1415
[Close]
BLAST of A disintegrin and metalloproteinase with thrombospondin motifs vs. Ensembl Zebrafish
Match: adamts9 (ADAM metallopeptidase with thrombospondin type 1 motif, 9 [Source:ZFIN;Acc:ZDB-GENE-070814-6])

HSP 1 Score: 357.066 bits (915), Expect = 1.108e-100
Identity = 347/1407 (24.66%), Postives = 566/1407 (40.23%), Query Frame = 1 
Query:  157 KERVQSG-EHLSMTLFCQSLISVLLNFNPFIYLEYHNSDGVFQWDNKLWFIKPNT--------KTKFNSKFLKTEMNFLPHKIYFTALNLNKPLFSCKLLKNNGYRNIP---------QESHFSRVFQRMKRETYPVVDSEIVEPNIIELLIVVTSNFVKRFKKDFRQYILSNVAIATKLLHDPTIKASITXXXXXXXXXXEDYERNNDLHDWSL-LSQDRVVSRFCHWVRQKKQLWN---YSWDSAILINDGVF-----SSNAIGIAHLRSMCND-NNCLAVVDRGFGTGFIIAHELAHQMNARHDFDNAEACSFFEKQYDNKTKYNTIMSTSLFFEYYPFIWSVCSQNVINSFLKSKYSFCLKQRNRHRNLYPHEQINEFFQKYSTGVDYDLNEQCSFAFGEKSEFCETDQNSRKKCSVLYCR----LKRYPICLRADAIIADGTECDVNQHCINGKCLYKNITIAPIDGGWSEYSEWSNCSRPCNGGVQFSYRTCDNPVPADGGRFCTGTKERIRSCNIEECS-SFSDPREESCGKYNLKPY----IPTNDEEFP----------CNLVCITTNHSLKYDI--SLTDGTPCSPFRSDICVKGTCYKTGCDRIVGSKKAIDNCNICAGQNDTCFKKESFFDGSKVAKVRMIRAFRIPPNVYNLFIKKVSQRMTPFTDEVYDDFELLLVVNRRTVIRRSETIEPLAGGQLR-------YSGSKNKVETISIKGKLNVGISI-VIKVEN-----TKTTLNLPF--ISYHYFVKDIFVWKYLEVITHPCKDQCGGFIEISPACFKKRDNQRYVDHYCSKATKPEPKIIKCGAICGYRWQRATEHYINSTVNKSCPIRCGTGKVKIPFVCQKINNQDDNNSLWETVEENLCFAVDLVDRPIEELNCVGQCNPLLWSYGKWEECPIECGTTFRYRNFICKDNKGLEWQKEWCERHLGLPDNKETCLSFNNCRNL--TRWVTSPWSRCSNSCESELQKRMVYCFRSEKSDEILDEKFLKIHEQISDAFCDIHSPKPITERPCSLNSCYFWIXXXXXXXXXXXXLGFRIQSHECKKKFNKNHEMITVDDKFCLKQNLVKPLDVRMRCFLKKCAI----------------ESFWIEMEWSKCSVSCGEGLQYRSLKCGYENENKTLTTWDNNEMCKNKMVPVSIQICKVTPCPKWIYSEWSECEGTCEYGSQHRTVLCTDPISEQILPDSKCDIKNKFPNFQKCLL----------------------SKLCG-------------HWIVGKWSQCSASCGLGVKTRTITCNYSNGSKSIDHSVCKSVAPFEEIHCQVKPCSTNAFWWLVKPSECYEYNCQPGIMYAHVRCVNRKFQVLYDSKCSRIKHPSYYVGCLNTTCR-RYFWTAESW 4023
            K  V +G EH ++   C  L+    +     ++E  +S     ++ +   IKP+         KT  +S   +T  +  P++ +   L    P      L+    R  P          ES  S+  +R KR         +  P  +E+++V  S  V+    + + YIL+ ++I + +  DP+I   I I +V +V++       N+L   ++  +    +  FC W + +    +      D+AILI            + +G+A L ++C+   +C    D G  T F IAHEL H  N  HD  N       + + D       +M+ +L +   P++WS CS+  I  FL + Y  CL      R     +Q+         G  Y +N+QC   FG  ++ C        +C  L+C     ++R   C       ADGT+C   +HC +G C++K     P++G W  +S +  CSR C GG++ + R C+ PVP +GG++C G + + RSCN E CS    D REE C  ++ + +    +P N    P          C L C     +  Y +   +TDGT C P  +DICV+G C + GCD ++ SK   D C +C G N +C      F+   +         RIP    N+ +++ S     ++ +  DD  L L  +R   +   + +  +   ++R       YSGS + VE I+   ++   I I V+ V N      + + N+P      H+F      W+   ++       C G  +    C ++ D     D  C    KP      C   C   W  A +          C   CG G   +   C K +  D      + V+E  C +     +P ++  C G CNP  W Y  W EC   CG   R RN IC  +          ER      N +  L+   C      +W T  WS C  +C    + R  +C   E              E++   FCD  S KP + + C    C  W     G+C+  CG G+++++ +C      +     +DD  C      +P D +  C L +C +                ++ W    W++CS +CG+G + R + C  +              C +   P + ++C +  C +W   EW+ C  +C  G+  R V+C + IS+Q++  S+CD+ +K    Q+C +                      + L G              W  G W  CS++C  G + R + C   NG  +I  S  +S+ P E+  C+   C     W+    SEC + +C  GI    V C     +   D  C  +  P     C   +C     W+ + W
Sbjct:  142 KGHVNAGQEHTAVISLCSGLLGTFRSPEGEFFVEPLHSYNSEHYEEE--HIKPHVVYRKDASKKTVDDSAACETSGHTEPNRRHRNRLKRKSPSSMLSDLETLNSRLFPFSENKHNSANESSDSKPHRRSKRF--------LSYPRFVEVMVVADSKMVEHHGSNLQHYILTLMSIVSSIYKDPSIGNLINIVIVKLVII------KNELDGPTISFNAQATLKNFCIWQQSQNHPDDNHPSHHDTAILITRQDICRARDKCDTLGLAELGTVCDPYRSCSINEDNGLSTAFTIAHELGHVFNMPHDDSN-------KCKEDGVKNQQHVMAPTLNYYTNPWMWSKCSRKYITEFLDTGYGECLLDEPVSRPYSLSQQL--------PGQIYSVNKQCELIFGPGTQVCPY----MTQCRRLWCTSPDGVQRG--CRTQHMPWADGTDCAPGKHCKHGLCIHKEHEYVPVEGAWGVWSPFGTCSRTCGGGIKIAVRECNRPVPRNGGKYCVGRRMKFRSCNSEPCSKQKKDFREEQCASFDGRHFNINGLPPNVRWVPKYSGILMKDRCKLFCRVAGSTAYYQLRDRVTDGTQCGPDTNDICVQGLCRQAGCDHVLNSKARRDKCGVCGGDNSSCKPVAGTFN---IVHYGYNVVVRIPSGATNIDVRQHS-----YSGKAEDDNYLALSNSRGEYLLNGDFVVSMFKREVRVGNAVIEYSGSDHVVERINCTDRIEEEIIIQVLSVGNLYNPDVRYSYNIPIEDKPQHFFWDAYGPWQDCSLL-------CQGERKKKILCNRESDRVVVSDQRCHGLPKPAAITESCNTDCELGWHIARK--------SECTAACGVGYRSLDIYCTKQSRLDGKT---QKVDERYCSS---QHKPNDKEVCHGDCNPGGWEYSSWSECSRSCGGGTRRRNAICGKSD---------ERDDDSKCNPQEKLTAQPCNEFLCPQWKTGDWSECLVTCGKGYKHRQTWCQFGE--------------ERLDVRFCD--SSKPESVQACQQQECASWQVGPWGQCTTTCGPGYQMRAVKCVVGSYGS----VMDDTEC--NAATRPTDTQ-DCELSQCPVTHPVAPEPKVMPHPGHKTQWRFGSWTQCSATCGKGTRMRYVSCRDQQGGVA-----EESACAHLPKPPASEVCSIVACGQWKVLEWTACSVSCGQGTTTRQVVCMN-ISDQVVELSECDLDDKPAAEQECAMPQCPSRSSDHGGFSPNPDFRKKTALPGRTDRNRAGRLQAQQWRTGPWGACSSTCAGGFQRRVVVCQDENGYPAI--SCDESIQPIEQRSCESGSCPQ---WFYGSWSECSK-SCGGGIKTRLVACQRPNGERFNDLSCEILDKPPDREQCNTQSCSINPHWSTDQW 1438

HSP 2 Score: 120.553 bits (301), Expect = 1.146e-26
Identity = 117/445 (26.29%), Postives = 186/445 (41.80%), Query Frame = 1 
Query: 2893 SPWSRCSNSCESELQKRMVYCFRSEKSDEILDEKFLKIHEQISDAFC-DIHSPKPITERPCSLNSCYFWIXXXXXXXXXXXXLGFRIQSHECKKKFNKNHEMITVDDKFCLKQNLVKPLDVRMRCFLKKCAIESFWIEMEWSKCSVSCGEGLQYRSLKCGYENENKTLTTWDNNEMCKNKMVPVSIQICKVTPCPKWIYSEWSECEGTCEYGSQHRTVLCTDPISEQILPDSKCDIKNKFPNFQKCLLSKLCGHWIVGKWSQCSASCGLGVKTRTITCNYSNGSKSIDHSVCKSVA-PFEEIHCQVKPCSTN----------------AFWWLVKPSECYEYNCQPGIMYAHVRCVNRKFQVLYDSKCSRIKHPSYYVGCLNTTCRRYFWTAESWDNIPCPDISCTMKIRNRDVYCVDDYGNIQKDAMCDQSDKPDTWRLCPSPQ 4173
             PW  CS  C+ E +K+++ C R  +SD ++          +SD  C  +  P  ITE  C+ +    W  ++  +C+A CG+G+R     C K+   + +   VD+++C  Q+  KP D  +            W    WS+CS SCG G + R+  CG  +E       D++  C N    ++ Q C    CP+W   +WSEC  TC  G +HR   C     E+ L    CD  +K  + Q C   + C  W VG W QC+ +CG G + R + C   +    +D + C +   P +   C++  C                     W     ++C    C  G    +V C +++  V  +S C+ +  P     C    C +  W    W       +SC      R V C++    + + + CD  DKP   + C  PQ
Sbjct:  872 GPWQDCSLLCQGERKKKIL-CNR--ESDRVV----------VSDQRCHGLPKPAAITES-CNTDCELGWHIARKSECTAACGVGYRSLDIYCTKQSRLDGKTQKVDERYCSSQH--KPNDKEV---CHGDCNPGGWEYSSWSECSRSCGGGTRRRNAICGKSDER------DDDSKC-NPQEKLTAQPCNEFLCPQWKTGDWSECLVTCGKGYKHRQTWCQ--FGEERLDVRFCD-SSKPESVQACQQQE-CASWQVGPWGQCTTTCGPGYQMRAVKCVVGSYGSVMDDTECNAATRPTDTQDCELSQCPVTHPVAPEPKVMPHPGHKTQWRFGSWTQC-SATCGKGTRMRYVSCRDQQGGVAEESACAHLPKPPASEVCSIVACGQ--WKVLEWTAC---SVSCGQGTTTRQVVCMNISDQVVELSECDLDDKPAAEQECAMPQ 1280

HSP 3 Score: 96.6709 bits (239), Expect = 1.847e-19
Identity = 81/326 (24.85%), Postives = 123/326 (37.73%), Query Frame = 1 
Query: 2701 WSYGKWEECPIECGTTFRYRNFICKDNKGLEWQKEWCERHLGLPDNKETCLSFNNCRNLTRWVTSPWSRCSNSCESELQKRMVYCFRSEKSDEILDEKFLKIHEQISDAFCDIHSPKPITERPCSLNSCYFWIXXXXXXXXXXXXLGFRIQSHECKKKFNKNHEMITVDDKFCLKQNLVKPLDVRMRCFLKKCAIESFWIEMEWSKCSVSCGEGLQYRSLKCGYENENKTLTTWDNNEMCKNKMVPVSIQICKVTPCPKWIYSEWSECEGTCEYGSQHRTVLCTDPISEQILPDSKCDIKNKFPNFQKCLLS--KLCGHWIVGKWS 3672
            W +G W +C   CG   R R   C+D +G   ++  C  HL  P   E C S   C    +W    W+ CS SC      R V C         + ++ +++ E      CD+   KP  E+ C++  C                              + +H   + +  F  K  L    D      L+       W    W  CS +C  G Q R + C  EN    ++       C   + P+  + C+   CP+W Y  WSEC  +C  G + R V C  P  E+   D  C+I +K P+ ++C      +  HW   +WS
Sbjct: 1172 WRFGSWTQCSATCGKGTRMRYVSCRDQQGGVAEESACA-HLPKPPASEVC-SIVAC---GQWKVLEWTACSVSCGQGTTTRQVVCMN-------ISDQVVELSE------CDLDD-KPAAEQECAMPQC---------------------------PSRSSDHGGFSPNPDFRKKTALPGRTDRNRAGRLQA----QQWRTGPWGACSSTCAGGFQRRVVVCQDENGYPAIS-------CDESIQPIEQRSCESGSCPQWFYGSWSECSKSCGGGIKTRLVACQRPNGER-FNDLSCEILDKPPDREQCNTQSCSINPHWSTDQWS 1439
[Close]
BLAST of A disintegrin and metalloproteinase with thrombospondin motifs vs. Ensembl Zebrafish
Match: adamts6 (ADAM metallopeptidase with thrombospondin type 1 motif, 6 [Source:ZFIN;Acc:ZDB-GENE-091113-9])

HSP 1 Score: 259.61 bits (662), Expect = 3.700e-70
Identity = 238/873 (27.26%), Postives = 363/873 (41.58%), Query Frame = 1 
Query:  541 IIELLIVVTSNFVK-RFKKDFRQYILSNVAIATKLLHDPTIKASITXXXXXXXXXXEDYERNNDLHDWSLLSQDRVVSRFCHWVRQKKQLWNYSWDSAILINDGVFSSN-------------------AIGIAHLRSMCN-DNNCLAVVDRGFGTGFIIAHELAHQMNARHD-FDNAEACSFFEKQYDNKTKYNTIMSTSLFFEYYPFIWSVCSQNVINSFLKSKYSFCLKQRNRHRN-LYPHEQINEFFQKYSTGVDYDLNEQCSFAFGEKSEFCETDQNSRKKCSVLYCRLKRYPICLRADAIIADGTECDVNQ----HCINGKCLYKNITIAPIDGGWSEYSEWSNCSRPCNGGVQFSYRTCDNPVPADGGRFCTGTKERIRSCNIEECSSFS-DPREESCGK----------YNLKPYIPTNDEEFPCNLVCITTNHSLKYDIS--LTDGTPCSPFRSDICVKGTCYKTGCDRIVGSKKAIDNCNICAGQNDTCFKKESFFDGSKVAKVRMIRAFRIPPNVYNLFIKKVSQRMTPFTDEVYDDFELLLVVNRRTVIRRSETIE-----PLAGGQLRYSGSKNKVETISIKGKL--NVGISIVIKVEN--TKTTLNLPFISYHYFVKDI-FVWKYLEVITHPCKDQC-GGFIEISPACFKKRDNQRYVDHYCSKATKPEPKIIKCGA-ICGYRWQRATEHYIN--STVNKSCPIRCGTGKVKIPFVCQKINNQDDNNSLWETVEENLCFAVDLVDRPIEELNCVGQCNPLLWSYGKWEECPIECGTTFRYRNFICKDNKGLE-WQKEWCERHLGLPDNKETCLSFNNCRNLTRWVTSPWSRCSNSCESELQKRMVYC--FRSEKSDEILD 2988
             +E L+V     V    +KD   YILS + I  KL  D ++   + I V  +++L ED       H       D+ +  FC W   +K + ++  D   +  +G+   +                    +G+A +  MC  + +C    D G G+ F IAHE+ H     HD   N+      E           +M+  +     PF WS CS++ I SFL S    CL      R+ LYP           + G  YD +EQC F +G  S  C+  +     C  L+C L +   C+      A+GT C  N      C  G+C+        +DG W  ++ W  CSR C GGV  S R CD+P P+ GG++C G ++R RSCN + C   S D RE+ C            YN KPY  T     PC L C+   ++   + S  + DGT C     DIC+ G C   GCD I+GS    D C +C G   TC   E  F+ S + +   +   +IP    ++ I++V+         V  ++  L        I  + TI+      +AG    Y    ++ E++   G    N+ + ++++ +N   +   N+P         ++ F W +L      C   C GG  +    C +  DN    + YC + +KP     +C    C   W      +I   S   K+C    G  + +     +KIN  ++     ET+E++ C    L  RPIE+ +C  Q  P  W    W EC  +CG  F++R  +CK +   + +    C  H   P  +  C S   C    RW+   W +CS  C    Q R V C  +  + S E LD
Sbjct:  250 FVETLVVADKMMVGYHGRKDIEHYILSVMNIVAKLYRDASLGNVVNIIVTRLIVLTEDQPNLEINH-----HADKSLDSFCKW---QKSILSHQGDGNSIPENGIAHHDNAVLITRYDICTYKNKPCGTLGLASVAGMCEPERSCSINEDIGLGSAFTIAHEIGHNFGMNHDGIGNSCGTKGHETA--------KLMAAHITANTNPFSWSACSKDYITSFLDSGRGTCLDNEPLKRDFLYP---------TVAPGQVYDADEQCRFQYGASSRQCKYGE----VCRELWC-LSKSNRCVTNSIPAAEGTLCQTNTIEKGWCYQGECVAFGTWPQSVDGSWGPWTVWGECSRTCGGGVSSSMRHCDSPAPSGGGKYCLGERKRYRSCNTDACPEGSRDFREKQCADFDSLPFRGKYYNWKPY--TGGGVKPCALNCLAEGYNFYTERSPAVIDGTRCQGDSLDICINGECKHVGCDNILGSDAKEDRCRVCGGDGSTCELTEGLFNDS-LPRGGYMEVVQIPKGSVHIEIREVA---------VSKNYIALKSEGDDYYINGAWTIDWPRKFDIAGTAFHYKRPTDEPESLEALGATMENLVVMVLLQEQNLGIQYKFNVPIQRTGSGDNEVGFSWHHLPW--SECSATCAGGSQKQEVVCKRLDDNSVVQNSYCDQDSKPPGNQRRCNTEPCPPEW------FIGDWSECGKTCD---GGIRTRTVLCIRKINPAEE-----ETLEDSHC----LTHRPIEQESCNNQSCPPQWVTLDWSECTPKCGPGFKHRIVLCKSSDLTKTFPAALCSDH-SKPPVRIRC-SLGRCPP-PRWIPGEWGQCSAQCGLGQQMRTVQCLSYTGQPSSECLD 1057

HSP 2 Score: 88.1965 bits (217), Expect = 6.650e-17
Identity = 71/251 (28.29%), Postives = 111/251 (44.22%), Query Frame = 1 
Query: 2884 WVTSPWSRCSNSCESELQKRMVYCFRSEKSDEILDEKFLKIHEQISDAFCDIHSPKPITERPCSLNSC-YFWIXXXXXXXXXXXXLGFRIQSHECKKKFNKNHEMITVDDKFCLKQNLVKPLDVRMRCFLKKCAIESFWIEMEWSKCSVSCGEGLQYRSLKCGYENENKTLTTWDNNEMCKNKMVPVSIQICKVTPC--PKWIYSEWSECEGTCEYGSQHRTVLCTDPISEQILPDSKCDIKNKFPNFQKC 3627
            W   PWS CS +C    QK+ V C R       LD+  +     + +++CD  S  P  +R C+   C   W      +C   C  G R ++  C +K N   E  T++D  CL     +P++ +  C  + C  +  W+ ++WS+C+  CG G ++R + C   +  KT        +C +   P     C +  C  P+WI  EW +C   C  G Q RTV C   +S    P S+C    +    Q+C
Sbjct:  843 WHHLPWSECSATCAGGSQKQEVVCKR-------LDDNSV-----VQNSYCDQDSKPPGNQRRCNTEPCPPEWFIGDWSECGKTCDGGIRTRTVLCIRKINPAEEE-TLEDSHCLTH---RPIE-QESCNNQSCPPQ--WVTLDWSECTPKCGPGFKHRIVLCKSSDLTKTFPA----ALCSDHSKPPVRIRCSLGRCPPPRWIPGEWGQCSAQCGLGQQMRTVQC---LSYTGQPSSECLDSLRPNTMQQC 1067

HSP 3 Score: 87.4261 bits (215), Expect = 1.277e-16
Identity = 56/185 (30.27%), Postives = 89/185 (48.11%), Query Frame = 1 
Query: 3199 TVDDKFCLKQNLVKPLDVRMRCFLKKCAIESFWIEMEWSKCSVSCGEGLQYRSLKCGYENENKTLTTWDNNEMCKNKMVPVSIQICKVTPCP-KWIYSEWSECEGTCEYGSQHRTVLCTDPISEQILPDSKCDIKNKFPNFQKCLLSKL-CGHWIVGKWSQCSASCGLGVKTRTITCNYSNGSKS 3747
             V + +C + +  KP   + RC  + C  E  W   +WS+C  +C  G++ R++ C  +       T +++    ++  P+  + C    CP +W+  +WSEC   C  G +HR VLC      +  P + C   +K P   +C L +     WI G+W QCSA CGLG + RT+ C    G  S
Sbjct:  874 VVQNSYCDQDS--KPPGNQRRCNTEPCPPE--WFIGDWSECGKTCDGGIRTRTVLCIRKINPAEEETLEDSHCLTHR--PIEQESCNNQSCPPQWVTLDWSECTPKCGPGFKHRIVLCKSSDLTKTFPAALCSDHSKPPVRIRCSLGRCPPPRWIPGEWGQCSAQCGLGQQMRTVQCLSYTGQPS 1052

HSP 4 Score: 86.6557 bits (213), Expect = 1.966e-16
Identity = 58/183 (31.69%), Postives = 85/183 (46.45%), Query Frame = 1 
Query: 3295 WIEMEWSKCSVSCGEGLQYRSLKCGYENENKTLTTWDNNEMCKNKMVPVSIQ-ICKVTPC-PKWIYSEWSECEGTCEYGSQHRTVLC---TDPISEQILPDSKC----DIKNKFPNFQKCLLSKLCGHWIVGKWSQCSASCGLGVKTRTITCNYSNGSKSIDHSVCKSVA-PFEEIHCQVKPC 3813
            W  + WS+CS +C  G Q + + C   ++N  +     N  C     P   Q  C   PC P+W   +WSEC  TC+ G + RTVLC    +P  E+ L DS C     I+ +  N Q C        W+   WS+C+  CG G K R + C  S+ +K+   ++C   + P   I C +  C
Sbjct:  843 WHHLPWSECSATCAGGSQKQEVVCKRLDDNSVV----QNSYCDQDSKPPGNQRRCNTEPCPPEWFIGDWSECGKTCDGGIRTRTVLCIRKINPAEEETLEDSHCLTHRPIEQESCNNQSCPP-----QWVTLDWSECTPKCGPGFKHRIVLCKSSDLTKTFPAALCSDHSKPPVRIRCSLGRC 1016

HSP 5 Score: 83.5741 bits (205), Expect = 1.901e-15
Identity = 67/245 (27.35%), Postives = 104/245 (42.45%), Query Frame = 1 
Query: 3478 WIYSEWSECEGTCEYGSQHRTVLCTDPISEQILPDSKCDIKNKFPNFQKCLLSKLC-GHWIVGKWSQCSASCGLGVKTRTITCNYS---NGSKSIDHSVCKSVAPFEEIHCQVKPCSTNAFWWLVKPSECYEYNCQPGIMYAHVRCVNRKFQVLYDSK-CSRIKHPSYYVGCLNTTCRRYFWTAESWDNIPCPDISCTMKIRNRDVYCVDDYGNIQKDAMCDQSDKPDTWRLCPSPQNCSNIPRS 4197
            W +  WSEC  TC  GSQ + V+C       ++ +S CD  +K P  Q+   ++ C   W +G WS+C  +C  G++TRT+ C         ++++ S C +  P E+  C  + C     W  +  SEC    C PG  +  V C +      + +  CS    P   + C    C    W    W         C +  + R V C+   G  Q  + C  S +P+T + C S   C + P S
Sbjct:  843 WHHLPWSECSATCAGGSQKQEVVCKRLDDNSVVQNSYCDQDSKPPGNQRRCNTEPCPPEWFIGDWSECGKTCDGGIRTRTVLCIRKINPAEEETLEDSHCLTHRPIEQESCNNQSCPPQ--WVTLDWSECTP-KCGPGFKHRIVLCKSSDLTKTFPAALCSDHSKPPVRIRCSLGRCPPPRWIPGEWGQC---SAQCGLGQQMRTVQCLSYTG--QPSSECLDSLRPNTMQQCES--KCDSTPIS 1077
[Close]
BLAST of A disintegrin and metalloproteinase with thrombospondin motifs vs. Ensembl Zebrafish
Match: adamts10 (ADAM metallopeptidase with thrombospondin type 1 motif, 10 [Source:ZFIN;Acc:ZDB-GENE-081104-414])

HSP 1 Score: 243.817 bits (621), Expect = 3.116e-65
Identity = 234/874 (26.77%), Postives = 352/874 (40.27%), Query Frame = 1 
Query:  487 RMKRETYPVVDSEIVEPNIIELLIVVTSNFVK-RFKKDFRQYILSNVAIATKLLHDPTIKASITXXXXXXXXXXEDYERNNDLHDWSLLSQDRVVSRFCHWVRQKKQLWNYSWDSAILINDGVFSSNAI------------------GIAHLRSMCN-DNNCLAVVDRGFGTGFIIAHELAHQMNARHDFDNAEACSFFEKQYDNKTKYNTIMSTSLFFEYYPFIWSVCSQNVINSFLKSKYSFCLKQRNRHRNLYPHEQINEFFQKYSTGVDYDLNEQCSFAFGEKSEFCETDQNSRKKCSVLYCRLKRYPICLRADAIIADGTECDVNQ----HCINGKCLYKNITIAPIDGGWSEYSEWSNCSRPCNGGVQFSYRTCDNPVPADGGRFCTGTKERIRSCNIEECSSFS-DPREESC---------GK-YNLKPYIPTNDEEFPCNLVCITTNHSL--KYDISLTDGTPCSPFRSDICVKGTCYKTGCDRIVGSKKAIDNCNICAGQNDTCFKKESFFDGSKVAKVRMIRAFRIPPNVYNLFIKKVSQRMTPFT-----DEVYDDFELLLVVNRRTVIRRSETIEPLAGGQLRYSGSKNKVETISIKGKLNVGISIVIKVENTKTTLNLPFISYHY---FVKD---IFVWKYLEVITHPCKDQCGGFIEISP-ACFKKRDNQRYVDHYCSKATKPEPKIIKCGA-ICGYRWQRATEHYINSTVNKSCPIRCGTGKVKIPFVCQKINNQDDNNSLWETVEENLCFAVDLVDRPIEELNCVGQCNPLLWSYGKWEECPIECGTTFRYRNFICKDNKGLEWQKEWCERHLGLPDNKETCLSFNNCRNLTRWVTSPWSRCSNSCESELQKRMVYCF 2958
            +M R   P+  S +     +E L+V     V    ++D  QYIL+ + I  KL  D ++  ++ I V  ++LL ED       H        + +  FC W  QK  L      +AI  N       A+                  G+A +  MC  + +C    D G  T F IAHE+ H     HD     AC    ++         +M+  +  +  PF+WS CS++ I +FL S    CL       N+ P ++    +   + G  YD +EQC F +G KS  C+  +     CS L+C + +   C+ +    A+GT C  +      C    C+        +DGGW  +S W  CSR C GGV  S R CD+P P  GG++C G ++R RSCNI+EC   S D RE  C         GK Y  KPY     +   C+L C+   ++   +   ++ DGTPC     D+CV G C   GCDRI+GS    D C +C G   +C   E  F+ S +++       RIP     + I++++  +         D+ + + +L +   RR  I         AGG   Y    N+ ET+   G  N+ + +++ V         P I Y +     +D    + W Y       C   C G +++    C K+ D     +H+C K  KP+ K   C    C   W        + + N     R    K K+    +K+            +++  C       RP     C     P  W    W EC   CG  +RYR  +C+     E   E        P  +  C +   C    +WV  PW  CS  C    + R V C 
Sbjct:  228 QMGRGQLPLKRS-VSRERFVETLVVADKMMVSYHGRRDIEQYILAVMNIVAKLFQDSSLGNAVNIVVTRLILLMEDQPTLEVNHH-----AGKSLDSFCKW--QKSILHRNGHGNAIPDNGIAHHDTAVLITRYDICIYKNKPCGTLGLAPVGGMCEPERSCSINEDIGLATAFTIAHEIGHTFGMNHD-GVGNACGVRSQETAK------LMAAHITMKTNPFVWSACSRDYITNFLDSGMGSCLN------NVPPKQEF--VYPTTAPGQAYDADEQCRFQYGVKSRQCKYGE----VCSELWC-MSKGNRCITSSIPAAEGTICQTSTIEKGWCYKRLCVPYGTRPEGVDGGWGHWSPWEECSRTCGGGVSSSIRHCDSPRPTVGGKYCLGERKRFRSCNIDECPVGSQDFREIQCSDFDSVPFRGKFYTWKPYRGGGVKS--CSLNCLAEGYNFYTERAPAVVDGTPCRDDSLDVCVNGECKHVGCDRILGSDVREDRCRVCGGDGSSCQVIEGVFNDS-LSEGGYEEVVRIPKGSVFIHIQELNISLNYLVLKSKGDQYFINGKLTIDTPRRFDI---------AGGTFHYRRPANEPETLEALGPTNMTLIVMVLVREEN-----PGILYRFNPPVSRDPLSSYSWHYTSWSR--CSALCAGGVQVQQVVCKKQADLSVVYNHFCDKKNKPKDKKRPCNQEPCPPTWWTGDWSECSRSCNGGVRTREVLCKRKMSVTEEKV------------LDDTACTTT----RPSVTEPCNNHTCPPEWHALDWSECTPGCGPGYRYRVILCRSGDNGETLPESECPKQSRPTTRVRC-NIQRCPP-PQWVAGPWGECSARCGMGQEIRFVQCL 1036

HSP 2 Score: 73.9442 bits (180), Expect = 1.597e-12
Identity = 43/153 (28.10%), Postives = 72/153 (47.06%), Query Frame = 1 
Query: 3295 WIEMEWSKCSVSCGEGLQYRSLKCGYENENKTLTTWDNNEMCKNKMVPVSIQICKVTPCP-KWIYSEWSECEGTCEYGSQHRTVLCTDPISEQILPDSKCDIKNKFPNFQKCLLSKL-CGHWIVGKWSQCSASCGLGVKTRTITCNYSNGSKS 3747
            W   +WS+CS SC  G++ R + C  +         D+      +  P   + C    CP +W   +WSEC   C  G ++R +LC    + + LP+S+C  +++     +C + +     W+ G W +CSA CG+G + R + C    G  S
Sbjct:  893 WWTGDWSECSRSCNGGVRTREVLCKRKMSVTEEKVLDDTACTTTR--PSVTEPCNNHTCPPEWHALDWSECTPGCGPGYRYRVILCRSGDNGETLPESECPKQSRPTTRVRCNIQRCPPPQWVAGPWGECSARCGMGQEIRFVQCLTHTGQPS 1043

HSP 3 Score: 73.559 bits (179), Expect = 2.203e-12
Identity = 62/235 (26.38%), Postives = 97/235 (41.28%), Query Frame = 1 
Query: 3295 WIEMEWSKCSVSCGEGLQYRSLKCGYENENKTLTTWDNNEMCKNKMVPVSIQICKVTPCPK-WIYSEWSECEGTCEYGSQHRTVLCTDPIS---EQILPDSKCDIKNKFPNFQKCLLSKLCG-HWIVGKWSQCSASCGLGVKTRTITCNYSNGSKSIDHSVC-KSVAPFEEIHCQVKPCSTNAFWWLVKP-SECYEYNCQPGIMYAHVRCVNRKFQVLYDSKCSRIKHPSYYVGC 3978
            W    WS+CS  C  G+Q + + C    +   L+   N+   K        + C   PCP  W   +WSEC  +C  G + R VLC   +S   E++L D+ C      P+  +   +  C   W    WS+C+  CG G + R I C   +  +++  S C K   P   + C ++ C      W+  P  EC    C  G     V+C+    Q    ++C     P++   C
Sbjct:  834 WHYTSWSRCSALCAGGVQVQQVVC---KKQADLSVVYNHFCDKKNKPKDKKRPCNQEPCPPTWWTGDWSECSRSCNGGVRTREVLCKRKMSVTEEKVLDDTACTTTR--PSVTEPCNNHTCPPEWHALDWSECTPGCGPGYRYRVILCRSGDNGETLPESECPKQSRPTTRVRCNIQRCPPPQ--WVAGPWGEC-SARCGMGQEIRFVQCLTHTGQP--SNECPESHRPAFMQQC 1058

HSP 4 Score: 69.707 bits (169), Expect = 2.763e-11
Identity = 69/254 (27.17%), Postives = 101/254 (39.76%), Query Frame = 1 
Query: 3478 WIYSEWSECEGTCEYGSQHRTVLCTDPISEQILPDSKCDIKNKFPNFQKCLLSKLCG-HWIVGKWSQCSASCGLGVKTRTITCNYS---NGSKSIDHSVCKSVAPFEEIHCQVKPCSTNAFWWLVKPSECYEYNCQPGIMYAHVRC-VNRKFQVLYDSKCSRIKHPSYYVGCLNTTCRRYFWTAESWDNIPCPDISCTMKIRNRDVYCVDDYGNIQKDAMCDQSDKPDTWRLCPSP---QNCSNIPRSCKELKS 4215
            W Y+ WS C   C  G Q + V+C       ++ +  CD KNK  + ++    + C   W  G WS+CS SC  GV+TR + C         K +D + C +  P     C    C     W  +  SEC    C PG  Y  + C      + L +S+C +   P+  V C    C    W A  W         C M    R V C+   G  Q    C +S +P   + C S       ++ P  CK++ +
Sbjct:  834 WHYTSWSRCSALCAGGVQVQQVVCKKQADLSVVYNHFCDKKNKPKDKKRPCNQEPCPPTWWTGDWSECSRSCNGGVRTREVLCKRKMSVTEEKVLDDTACTTTRPSVTEPCNNHTCPPE--WHALDWSECTP-GCGPGYRYRVILCRSGDNGETLPESECPKQSRPTTRVRCNIQRCPPPQWVAGPWGEC---SARCGMGQEIRFVQCLTHTG--QPSNECPESHRPAFMQQCKSKCDHSGPTDNPEECKDVNT 1079

HSP 5 Score: 59.6918 bits (143), Expect = 3.329e-8
Identity = 69/260 (26.54%), Postives = 105/260 (40.38%), Query Frame = 1 
Query: 2701 WSYGKWEECPIECGTTFRYRNFICKDNKGLEW-QKEWCERHLGL-----PDNKETCLSFNNCRNLTRWVTSPWSRCSNSCESELQKRMVYCFRSEKSDEILDEKFLKIHEQISDAFCDIHSPKPITERPCSLNSC-YFWIXXXXXXXXXXXXLGFRIQSHECKKKFNKNHEMITVDDKFCLKQNLVKPLDVRMRCFLKKCAIESFWIEMEWSKCSVSCGEGLQYRSLKCGYENENKTLTTWDNNEMCKNKMVPVSIQICK 3459
            W Y  W  C   C    + +  +CK    L      +C++         P N+E C           W T  WS CS SC   ++ R V C R      + +EK L       D  C   + +P    PC+ ++C   W      +C+  CG G+R +   C+   N      T+ +  C KQ+  +P   R+RC +++C     W+   W +CS  CG G + R ++C       T T   +NE C     P  +Q CK
Sbjct:  834 WHYTSWSRCSALCAGGVQVQQVVCKKQADLSVVYNHFCDKKNKPKDKKRPCNQEPCPP--------TWWTGDWSECSRSCNGGVRTREVLCKRKMS---VTEEKVL------DDTACT--TTRPSVTEPCNNHTCPPEWHALDWSECTPGCGPGYRYRVILCRSGDNGE----TLPESECPKQS--RPT-TRVRCNIQRCPPPQ-WVAGPWGECSARCGMGQEIRFVQC------LTHTGQPSNE-CPESHRPAFMQQCK 1059
[Close]
BLAST of A disintegrin and metalloproteinase with thrombospondin motifs vs. Ensembl Zebrafish
Match: adamts18 (ADAM metallopeptidase with thrombospondin type 1 motif, 18 [Source:ZFIN;Acc:ZDB-GENE-070815-1])

HSP 1 Score: 244.588 bits (623), Expect = 5.067e-65
Identity = 225/875 (25.71%), Postives = 367/875 (41.94%), Query Frame = 1 
Query:  454 PQESHF---SRVFQRMKRETYPVVDSEIVEPNIIELLIVVTSNFVKRFKKDFRQYILSNVAIATKLLHDPTIKASITXXXXXXXXXXEDYERNNDLHDWSLLSQDRVVSRFCHWVRQKKQLWNYSWDSAILINDGVFSS------NAIGIAHLRSMCND-NNCLAVVDRGFGTGFIIAHELAHQMNARHDFDNAEACSFFEKQYDNKTKYNTIMSTSLFFEYYPFIWSVCSQNVINSFLKSKYSFCLKQRNRHRNLYPH-EQINEFFQKYSTGVDYDLNEQCSFAFGEKSEFCETDQNSRKKCSVLYCRLKRYPICLRADAIIADGTECDVNQHCINGKCL-YKNITIAPIDGGWSEYSEWSNCSRPCNGGVQFSYRTCDNPVPADGGRFCTGTKERIRSCNIEECSSFS-DPREESCGKYNLKPY---------IPTNDEEFPCNLVCITTNHSLKYDIS--LTDGTPCSPFRSDICVKGTCYKTGCDRIVGSKKAIDNCNICAGQNDTCFKKESFFDGSKVAKVRMIRAF---RIPPNVYNLFIKKVSQRMTPFTDEVYDDFELLLVVNRRTVIRRSE-TIE-----PLAGGQLRYSGSKNKVETISIKGKLNVGISIVIKVENTKTTLNLPFISYHYFVKDIFVWKYLEVITHPCKDQC-GGFIEISPACFKKRDNQRYVDHYCSKATKPEPKIIKCGAICGYRWQRATEHYINSTVNKSCPIRCGTGKVKIPFVC-QKINNQDDNNSLWETVEENLCFAVDLVDRPIEELNCVGQCNPLLWSYGKWEECPIECGTTFRYRNFICKDN----KGLEWQKEWCERHLGLPDNKETCLSFNNCRNLTR--WVTSPWSRCSNSCESELQKRMVYC 2955
            P E HF       Q+++ +   +  S+    N+  L++       K  + +   Y+L+ + + + L  D TI   I I VV ++LL++D    +  H       D+ ++ FC W            D AIL+      S      + +G A +  MC+   +C    D G G  F IAHE  H     HD +              KT+ N IMS +L      F WS CS+  +N FL +  + CL    +    Y + EQ+         G  YD + QC + FG K++ C  D   +  C  L+C    +  C       A+GT C  +  C  G+C+ + +     + G WS +SEWS+CSR C GGV +  R+C++P P   G+FC G     + CN + C     D R + C +YN KP+             +EE  C L CI  +    + +S  + DGT CS ++  +C+ G C   GCD+++GSK A+D C +C G N TC     F+ G    + R    +    +P    ++ ++++         E+ + +  +  + R T    ++ T++       AG    Y  S N+ ET+   G  N  +   I ++     +   +   H   K  + W    V+   C   C GG +     C +  D Q  V+   S    P+ + +    +C     +    Y  +     C   CG G+      C +K+  Q +     E   ++LC     V  P +   C  Q  P  WS   W +C   CG   + R+  C+      + +      C+ HL  P  +E+C+  + C    R  W+TS W  CS SC + +++R ++C
Sbjct:  269 PTEDHFVMPDEFEQQIRVKRSEITSSKEGGLNVETLVVADRKMLEKHGRDNVTTYVLTVMNMVSSLFKDGTIGNDINIVVVSLLLLEKDPLGLSINHH-----ADQSLNSFCQWQSGLVGKNGKRHDHAILLTGLDICSWKNEPCDTLGFAPISGMCSKYRSCTINEDTGLGLAFTIAHESGHNFGMIHDGEGNPC---------RKTEGN-IMSPTLAGNNGVFSWSACSRQYLNRFLGTAQASCLVDEPKQIGQYKYPEQL--------PGQLYDADIQCKWQFGSKAKLCGLD-FVKDICKSLWCHRTGH-RCETKFMPAAEGTICGADMWCRKGQCVKFGDHGPKAVHGQWSGWSEWSDCSRTCGGGVMYRERSCNSPSPQHNGKFCQGPGRLHQLCNTKPCQPDGVDFRAQQCAEYNSKPFRGWYYKWKPYTKVEEEDICKLYCIAEDFDFFFAMSSKVKDGTSCSDYKGGVCIDGICEPVGCDQVLGSKAALDACGVCKGDNSTC----KFYSGQYTLQHRANEYYPVVMVPAGARSIQVQEM---------EISNSYLAVRSLKRGTYYLTADWTVDWPGRFQFAGTTFNYQRSFNRPETLFATGPTNETLLFEILLQGKNPGITWEYTLPHPEKKHNYTW---SVVRSDCSAPCAGGRVSTKAICLQ--DQQTQVN---SSLCNPQTRPVVGSHLCN---TQPCPAYWTTGKWGVCSRTCGGGQQTRNIRCLRKVTYQRE-----EVAAQSLC----PVMAPAQLQPCNTQSCPPEWSTSSWTQCSKTCGRGLKKRSVFCRSTDPGARAVVVPDSMCKLHL-KPKAQESCV-LSRCPKNERLQWITSAWGECSASCGAGVRRRELHC 1083

HSP 2 Score: 90.8929 bits (224), Expect = 9.926e-18
Identity = 67/238 (28.15%), Postives = 104/238 (43.70%), Query Frame = 1 
Query: 3190 EMITVDDKFCLKQNLVKPLDVRMRCFLKKCAIESFWIEMEWSKCSVSCGEGLQYRSLKCGYENENKTLTTWDNNEMCKNK----MVPVSIQICKVTPCP-KWIYSEWSECEGTCEYGSQHRTVLC--TDPISEQIL-PDSKCDIKNKFPNFQKCLLSKLCG----HWIVGKWSQCSASCGLGVKTRTITC---NYSNGSKSIDHSVCKSVAPFE---EIHCQVKPCSTNAFWWLVKPS 3849
            +   V+   C  Q   +P+     C  + C   ++W   +W  CS +CG G Q R+++C  +       T+   E+        M P  +Q C    CP +W  S W++C  TC  G + R+V C  TDP +  ++ PDS C +  K    + C+LS+        WI   W +CSASCG GV+ R + C   +   G        C+++   E   E  C   PC       L++P 
Sbjct:  904 QQTQVNSSLCNPQ--TRPVVGSHLCNTQPCP--AYWTTGKWGVCSRTCGGGQQTRNIRCLRK------VTYQREEVAAQSLCPVMAPAQLQPCNTQSCPPEWSTSSWTQCSKTCGRGLKKRSVFCRSTDPGARAVVVPDSMCKLHLKPKAQESCVLSRCPKNERLQWITSAWGECSASCGAGVRRRELHCGEKDSQGGYTEFPARRCRNLQKPEADLEQSCNNGPCPEPLAPQLLQPG 1131

HSP 3 Score: 70.4774 bits (171), Expect = 2.048e-11
Identity = 66/244 (27.05%), Postives = 98/244 (40.16%), Query Frame = 1 
Query: 2884 WVTSPWSRCSNSCESELQKRMVYCFRSEKSDEILDEKFLKIHEQISDAFCDIHSPKPITERPCSLNSC-YFWIXXXXXXXXXXXXLGFRIQSHECKKKFNKNHEMITVDDKFCLKQNLVKPLDVRMRCFLKKCAIESF--WIEMEWSKCSVSCGEGLQYRSLKCGYENENKTLTTWDNNEMCKNKMVPVSI--QICKVTPCPK-----------------WIYSEWSECEGTCEYGSQHRTVLC 3549
            W T  W  CS +C    Q R + C R         +   +  E  + + C + +P  +  +PC+  SC   W  S   +CS  CG G + +S  C+   +     + V D  C     +KP   +  C L +C       WI   W +CS SCG G++ R L CG ++     T +     C+N   P +   Q C   PCP+                 W  S W +C  +C  G Q R+V C
Sbjct:  935 WTTGKWGVCSRTCGGGQQTRNIRCLR---------KVTYQREEVAAQSLCPVMAPAQL--QPCNTQSCPPEWSTSSWTQCSKTCGRGLKKRSVFCRST-DPGARAVVVPDSMCKLH--LKP-KAQESCVLSRCPKNERLQWITSAWGECSASCGAGVRRRELHCGEKDSQGGYTEFPARR-CRNLQKPEADLEQSCNNGPCPEPLAPQLLQPGGPSVTLGWYSSPWLQCTVSCGGGVQTRSVQC 1162
[Close]
BLAST of A disintegrin and metalloproteinase with thrombospondin motifs vs. Ensembl Xenopus
Match: ADAMTS9 (ADAM metallopeptidase with thrombospondin type 1 motif 9 [Source:NCBI gene;Acc:493280])

HSP 1 Score: 453.366 bits (1165), Expect = 1.289e-131
Identity = 428/1702 (25.15%), Postives = 652/1702 (38.31%), Query Frame = 1 
Query:  271 GVFQWDNKLWFIKPNTKTKFNSKFLKTEMNFLPHKIYF---TALNLNKPLFSCKLLKNNGYRNIPQESHFSRVFQRMKRETYPVVDSEIVEPNIIELLIVVTSNFVKRFKKDFRQYILSNVAIATKLLHDPTIKASITXXXXXXXXXXEDYERNNDLHDWSLLSQDRVVSRFCHWVRQKKQLWN---YSWDSAILIND-----GVFSSNAIGIAHLRSMCND-NNCLAVVDRGFGTGFIIAHELAHQMNARHDFDNAEACSFFEKQYDNKTKYNTIMSTSLFFEYYPFIWSVCSQNVINSFLKSKYSFCLKQRNRHRNLYPHEQINEFFQKYSTGVDYDLNEQCSFAFGEKSEFCETDQNSRKKCSVLYC--RLKRYPICLRADAIIADGTECDVNQHCINGKCLYKNITIAPIDGGWSEYSEWSNCSRPCNGGVQFSYRTCDNPVPADGGRFCTGTKERIRSCNIEECSSFS-DPREESCGKYNLKPY----IPTNDEEFP----------CNLVCITTNHSLKYDI--SLTDGTPCSPFRSDICVKGTCYKTGCDRIVGSKKAIDNCNICAGQNDTCFKKESFFDGSKVAKVRMIRAFRIPPNVYNLFIKKVSQRMTPFTDE--VYDDFELLLVVNRRTVIRRSETIEPLAGGQLRYSGSKNKVETISIKGKLNVGISI-VIKVEN-----TKTTLNLPF--ISYHYFVKDIFVWKYLEVITHPCKDQCGGFIEISPACFKKRDNQRYVDHYCSKATKPEPKIIKCGAICGYRWQRATEHYINSTVNKSCPIRCGTGKVKIPFVCQKINNQDDNNSLWETVEENLCFAVDLVDRPIEELNCVGQCNPLLWSYGKWEECPIECGTTFRYRNFICKD------------------------------------------NKGLEWQKEWCE-----RHLGLPDNKETCLSFNNCRN--LTRWVTSPWSRCSNSCESELQKRMVYCFRSEKSDEILDEKFLKIHEQISDAFCDIHSPKPITERPCSLNSCYFWIXXXXXXXXXXXXLGFRIQSHECKKKFNKNHEMITVDDKFCLKQNLVKPLDVRMRCFLKKCAIESFWIEMEWSKCSVSCGEGLQYRSLKCGYENENKTLTTWDNNEMCKNKMVPVSIQICKVTPC------------------------------------------PKWIYSEWSECEGTCEYGSQHRTVLCTDPISEQILPDSKCDIKNKFPNFQKCLLSKLCGHWIVGKWSQCSASCGLGVKTRTITCNYSNGSKSIDHSVCKSVAPFEEIHCQVKPCSTNAFW----W------------------------LVKPSECYEY---------------------------NCQPGIMYAHVRCVNRKFQVLYDSKCSRIKHPSYYVGCLNTTCRRYFWTAESWDNIP--------------CP-DISCTMKIRNRDVYCVDDYGNIQKDAMCDQSDKPDTWRLCPSPQNCSNIPRSCKELKSRQSVSKDGEYSLAIDLNWAYFIYCADMNTEEPKEYLTL---RELNYARTSKYVSTDVSSCIYEEEMEFNQKCPTCKINENLWSITYYNKIRINLSDLSIDVMDDRFSATNGQSFIPFGTAKDCAGSTSCPKGHFKINLRGTGFSVSMETRWNEVYPKYGYR-ILRKQTSQIVKGWCGGHCSGCSP 4758
            G F+  +  +F++P      +      E +  PH +Y       N+++   +C     N   N    +  +R  +R KR         +  P  +E+++V  +  V+    + + Y+L+ ++I   +  DP+I   I I +V + ++ ++ E           +    +  FC W + +    +      D+A+LI            + +G+A L ++C+   +C    D G  T F IAHEL H  N  HD  N   C    K+   K + + +M+ +L F   P++WS CS+  +  FL + Y  CL      R     +Q+         G  Y++N+QC   FG  S+ C   Q    +C  L+C     ++  C       ADGTEC+  +HC  G C+ K   +   DG W  +S +  CSR C GG++ S R C+ P P +GG++C G + + +SCN E C+    D REE C  ++ K +    +P N    P          C L C     +  Y +   + DGT C P  +DICV+G C + GCD ++ SK   D C +C G N +C      ++   +         RIP    NL +++ S    P  D      +     ++N   V+   +    +    + YSGS N +E I+   ++   I + ++ V N      + T N+P       ++      W+       PC   C G  +  P C +  D     D  C +  +PEP    C   C  RW  A +          C ++CG G   +   C K    D  N   E V+E  C     + +P+ +  C G CN   W Y  W EC   CGT  R R  IC +                                           KG + ++ WC+      H    D +    S   C       W   PW +C+ +C    Q R+V C        + D +            C+  +   I E    ++S   W       CSA CG G R++   C     ++ +    D+  C +  L KPL     C +  C     W  +EWS CSV+CG+G   R + C  +  ++T+   D +E C    VP   Q C ++PC                                           +W    W  C  TC  G Q R V+C D   E   P S CD K K P  Q+   S  C  W  G W +CS  CG G +TR + C  SNG    D S      P +   C +  C     W    W                         V+P  C                               C  GI    V C     ++  +S+C +   P     C    C  Y W AE W  +               CP  ++C   +  R V C+ +        MC    KP+  R+C S  +C     SC +LK    V  DGE+ + I       IYCA M +E PKEY+TL      NY+    Y   + + C Y      + +   CK +      + ++K+R+++  L I   D  F+ T     +PF TA DC  +  CP+G F INL GTG S+S   +W     +  Y  +   Q    V G CGG+C  C P
Sbjct:  142 GTFKSQDGDYFVEP----LLSDDSEYEEEHNKPHVVYRHNPPHRNISREEQTCH---TNPLFNKADNATGTRTLRRKKRF--------LSYPRYVEVMVVADNKMVEYHGANLQHYVLTLMSIVASIYKDPSIGNLINIAIVKLAVVHDEQE-----GPAISFNAQSTLKNFCIWQQSQNNPDDNHPSHHDTAVLITRQDICRAQEKCDTLGLAELGTVCDPYRSCSISEDNGLSTAFTIAHELGHVFNMPHDDSNK--C----KEESGKNQQH-VMAPTLNFYTNPWMWSKCSRKYVTQFLDTGYGECLLDEPISRTYTLPQQL--------PGALYNVNKQCELIFGPGSQVCPYMQ---MQCRRLWCISSDGQHKGCRTQHTPWADGTECEPGKHCRYGVCIPKERDVQIADGSWGSWSPFGACSRSCGGGIKTSIRECNRPEPKNGGKYCVGRRMKFKSCNTELCAKHKRDFREEQCADFDGKHFNINGLPPNVRWVPKYSGILMKDRCKLFCRVAGSTAYYQLRDRVVDGTSCGPDTNDICVQGLCRQAGCDHVLNSKARRDKCGVCGGDNSSCKTIAGTYN---IVHYGYNSVVRIPAGATNLDVRQHSYSGKPEDDNYLALSNSHGEFLLNGDFVVSMFKREIKVGNAVIEYSGSDNAIERINCTDRIEQEIVLQILSVGNLYNPDVRYTFNIPIEDKPQQFYWNPYGPWQ-------PCNKMCQGERKQKPVCIRDSDQLVVSDQRCDRIPQPEPVTEPCNTECEVRWHVARK--------SECTVQCGLGYRTLDIHCAKYTRADGKN---EKVDERYC---SHLQKPLTKEKCSGDCNTGGWRYSPWSECSKSCGTGTRRRRAICVNALHDILDDSKCGQQEKPTEQRCSEFPCPQWKTGDWSDCLVTCGKGHKHRQTWCQFGDDRLHDRFCDTETKPESVEACEQPECASWQVGPWGQCTAACGPGYQMRVVKCVVGAYRAVVDDSECNAATRPTDTQDCEADACPGIPETKQIVHSRTQWRFGSWTPCSATCGKGTRMRYVSC-----RDDQGSVADEAACAQ--LPKPLATEA-CSVTPCGQ---WKALEWSSCSVTCGQGKATRQVIC-VDFADQTV---DGSE-CDPDDVPAVEQECSMSPCYYLNHDYSKPIQTVPNTDHRIRSNPTLAILNRNTGRPAGSGGSQWRTGPWGACSSTCAGGFQRRVVVCQD---ENGYPASNCDEKTK-PIEQRSCESGSCPQWAFGNWGECSKKCGGGTRTRQVVCQRSNGDIFNDLSCEILDKPPDREQCNMHSCPRETGWNSGPWNVCSVSCGRGVKTRPVYCVTKEGVTVEPENCKHLAKPNIQKKCRGGKCPKWKAGEWEKCSVTCGRGIQQRAVHCQVGAQKMSRESECPQHARPPSEQYCQVAECPLYTWKAEEWQEVSGSWEGRATLAMYQICPCSVTCGSGVTQRSVQCLTN--EDLPSNMCSVDQKPEEKRICYSNHDCKICFISCLKLK---HVGADGEHYVMIQEK-IIKIYCAGMQSESPKEYITLLSGEAENYSEVYGYRLQNPTECPYNGSRREDCQ---CKKDYTAAGFSTFSKVRLDVVTLQIITTDLHFARTQDGRPVPFATAGDCYSAAKCPQGRFSINLLGTGLSISETAKW---MSQGNYAPVTSSQDGTKVTGRCGGYCGKCVP 1749
[Close]
BLAST of A disintegrin and metalloproteinase with thrombospondin motifs vs. Ensembl Xenopus
Match: ADAMTS9 (ADAM metallopeptidase with thrombospondin type 1 motif 9 [Source:NCBI gene;Acc:493280])

HSP 1 Score: 382.104 bits (980), Expect = 1.630e-107
Identity = 348/1384 (25.14%), Postives = 538/1384 (38.87%), Query Frame = 1 
Query:  397 LNKPLFSCKLLKNNGYRNIPQESHFSRVFQRMKRETYPVVDSEIVEPNIIELLIVVTSNFVKRFKKDFRQYILSNVAIATKLLHDPTIKASITXXXXXXXXXXEDYERNNDLHDWSLLSQDRVVSRFCHWVRQKKQLWN---YSWDSAILIND-----GVFSSNAIGIAHLRSMCND-NNCLAVVDRGFGTGFIIAHELAHQMNARHDFDNAEACSFFEKQYDNKTKYNTIMSTSLFFEYYPFIWSVCSQNVINSFLKSKYSFCLKQRNRHRNLYPHEQINEFFQKYSTGVDYDLNEQCSFAFGEKSEFCETDQNSRKKCSVLYC--RLKRYPICLRADAIIADGTECDVNQHCINGKCLYKNITIAPIDGGWSEYSEWSNCSRPCNGGVQFSYRTCDNPVPADGGRFCTGTKERIRSCNIEECSSFS-DPREESCGKYNLKPY----IPTNDEEFP----------CNLVCITTNHSLKYDI--SLTDGTPCSPFRSDICVKGTCYKTGCDRIVGSKKAIDNCNICAGQNDTCFKKESFFDGSKVAKVRMIRAFRIPPNVYNLFIKKVSQRMTPFTDE--VYDDFELLLVVNRRTVIRRSETIEPLAGGQLRYSGSKNKVETISIKGKLNVGISI-VIKVEN-----TKTTLNLPF--ISYHYFVKDIFVWKYLEVITHPCKDQCGGFIEISPACFKKRDNQRYVDHYCSKATKPEPKIIKCGAICGYRWQRATEHYINSTVNKSCPIRCGTGKVKIPFVCQKINNQDDNNSLWETVEENLCFAVDLVDRPIEELNCVGQCNPLLWSYGKWEECPIECGTTFRYRNFICKD------------------------------------------NKGLEWQKEWCE-----RHLGLPDNKETCLSFNNCRN--LTRWVTSPWSRCSNSCESELQKRMVYCFRSEKSDEILDEKFLKIHEQISDAFCDIHSPKPITERPCSLNSCYFWIXXXXXXXXXXXXLGFRIQSHECKKKFNKNHEMITVDDKFCLKQNLVKPLDVRMRCFLKKCAIESFWIEMEWSKCSVSCGEGLQYRSLKCGYENENKTLTTWDNNEMCKNKMVPVSIQICKVTPC------------------------------------------PKWIYSEWSECEGTCEYGSQHRTVLCTDPISEQILPDSKCDIKNKFPNFQKCLLSKLCGHWIVGKWSQCSASCGLGVKTRTITCNYSNGSKSIDHSVCKSVAPFEEIHCQVKPCSTNAFWWLVKPSECYEYNCQPGIMYAHVRCVNRKFQVLYDSKCSRIKHPSYYVGCLNTTCRRYFWTAESWDNIPCPDISCTMKIRNRDVYCVDDYGNIQKDAMCDQSDKPDTWRLC 4161
            LNK L    L   N   N    +  +R  +R KR         +  P  +E+++V  +  V+    + + Y+L+ ++I   +  DP+I   I I +V + ++ ++ E           +    +  FC W + +    +      D+A+LI            + +G+A L ++C+   +C    D G  T F IAHEL H  N  HD  N   C    K+   K + + +M+ +L F   P++WS CS+  +  FL + Y  CL      R     +Q+         G  Y++N+QC   FG  S+ C   Q    +C  L+C     ++  C       ADGTEC+  +HC  G C+ K   +   DG W  +S +  CSR C GG++ S R C+ P P +GG++C G + + +SCN E C+    D REE C  ++ K +    +P N    P          C L C     +  Y +   + DGT C P  +DICV+G C + GCD ++ SK   D C +C G N +C      ++   +         RIP    NL +++ S    P  D      +     ++N   V+   +    +    + YSGS N +E I+   ++   I + ++ V N      + T N+P       ++      W+       PC   C G  +  P C +  D     D  C +  +PEP    C   C  RW  A +          C ++CG G   +   C K    D  N   E V+E  C     + +P+ +  C G CN   W Y  W EC   CGT  R R  IC +                                           KG + ++ WC+      H    D +    S   C       W   PW +C+ +C    Q R+V C        + D +            C+  +   I E    ++S   W       CSA CG G R++   C     ++ +    D+  C +  L KPL     C +  C     W  +EWS CSV+CG+G   R + C  +  ++T+   D +E C    VP   Q C ++PC                                           +W    W  C  TC  G Q R V+C D   E   P S CD K K P  Q+   S  C  W  G W +CS  CG G +TR + C  SNG    D S      P +   C +  C      W   P      +C  G+    V CV ++   +    C  +  P+    C    C +  W A  W+      ++C   I+ R V+C      + +++ C Q  +P + + C
Sbjct:  212 LNKGL----LGTQNPLFNKADNATGTRTLRRKKRF--------LSYPRYVEVMVVADNKMVEYHGANLQHYVLTLMSIVASIYKDPSIGNLINIAIVKLAVVHDEQE-----GPAISFNAQSTLKNFCIWQQSQNNPDDNHPSHHDTAVLITRQDICRAQEKCDTLGLAELGTVCDPYRSCSISEDNGLSTAFTIAHELGHVFNMPHDDSNK--C----KEESGKNQQH-VMAPTLNFYTNPWMWSKCSRKYVTQFLDTGYGECLLDEPISRTYTLPQQL--------PGALYNVNKQCELIFGPGSQVCPYMQ---MQCRRLWCISSDGQHKGCRTQHTPWADGTECEPGKHCRYGVCIPKERDVQIADGSWGSWSPFGACSRSCGGGIKTSIRECNRPEPKNGGKYCVGRRMKFKSCNTELCAKHKRDFREEQCADFDGKHFNINGLPPNVRWVPKYSGILMKDRCKLFCRVAGSTAYYQLRDRVVDGTSCGPDTNDICVQGLCRQAGCDHVLNSKARRDKCGVCGGDNSSCKTIAGTYN---IVHYGYNSVVRIPAGATNLDVRQHSYSGKPEDDNYLALSNSHGEFLLNGDFVVSMFKREIKVGNAVIEYSGSDNAIERINCTDRIEQEIVLQILSVGNLYNPDVRYTFNIPIEDKPQQFYWNPYGPWQ-------PCNKMCQGERKQKPVCIRDSDQLVVSDQRCDRIPQPEPVTEPCNTECEVRWHVARK--------SECTVQCGLGYRTLDIHCAKYTRADGKN---EKVDERYC---SHLQKPLTKEKCSGDCNTGGWRYSPWSECSKSCGTGTRRRRAICVNALHDILDDSKCGQQEKPTEQRCSEFPCPQWKTGDWSDCLVTCGKGHKHRQTWCQFGDDRLHDRFCDTETKPESVEACEQPECASWQVGPWGQCTAACGPGYQMRVVKCVVGAYRAVVDDSECNAATRPTDTQDCEADACPGIPETKQIVHSRTQWRFGSWTPCSATCGKGTRMRYVSC-----RDDQGSVADEAACAQ--LPKPLATEA-CSVTPCGQ---WKALEWSSCSVTCGQGKATRQVIC-VDFADQTV---DGSE-CDPDDVPAVEQECSMSPCYYLNHDYSKPIQTVPNTDHRIRSNPTLAILNRNTGRPAGSGGSQWRTGPWGACSSTCAGGFQRRVVVCQD---ENGYPASNCDEKTK-PIEQRSCESGSCPQWAFGNWGECSKKCGGGTRTRQVVCQRSNGDIFNDLSCEILDKPPDREQCNMHSCPRETG-WNSGPWNVCSVSCGRGVKTRPVYCVTKEGVTVEPENCKHLAKPNIQKKCRGGKCPK--WKAGEWEKC---SVTCGRGIQQRAVHCQVGAQKMSRESECPQHARPPSEQYC 1510

HSP 2 Score: 204.142 bits (518), Expect = 5.014e-52
Identity = 231/835 (27.66%), Postives = 339/835 (40.60%), Query Frame = 1 
Query: 2323 PCKDQCGGFIEIS-PACFKKRDNQRYVDHYCSKATKPEP------KIIKCGAICGYRWQRATEHYINSTVNKSCPIRCGTGKVKIPFVCQKINNQDDNNSLWETVEENLCFAVDLVDRPIEELNC-VGQCNPLLWSYGKWEECPIECGTTFRYRNFICKDNKGLEWQKEWCERHLGLPDNKETCLSFNNCRNLTRWVTSPWSRCSNSCESELQKRMVYCFRSEKSDEILDEKFLKIHEQISDAFCDIHSPKPITERPCSLNSCYFWIXXXXXXXXXXXXLGFRIQSHECKKKFNKNHEMITVDDKFCLKQNLVKPLDVRMRCFLKKCAIESFWIEMEWSKCSVSCGEGLQYRSLKCGYENENKTLTTWDNNEMCKNKMVPVSIQICKVTPCPKWIYSEWSECEGTCEYGSQHRTVLCTDPISEQILPDSKCDIKNKFPNFQKCLLSKLCGH-WIVGKWSQCSASCGLGVKTRTITCNYSNGSKSIDHSVCK-SVAPFEEIHCQVKPCSTNAFWWLVKP-SECYEYNCQPGIMYAHVRCVNRKFQVLYDSKCSRIKHPSY-YVGCLNTTCRRYFWTAESWDN--------IPCPDISCTMKIRNRDVYCVDDYGNIQKDAMCDQSDKPDTWRLCPSPQNCSNIPRSCKELKSRQSVSKDGEYSLAIDLNWAYFIYCADMNTEEPKEYLTL---RELNYARTSKYVSTDVSSCIYEEEMEFNQKCPTCKINENLWSITYYNKIRINLSDLSIDVMDDRFSATNGQSFIPFGTAKDCAGSTSCPKGHFKINLRGTGFSVSMETRWNEVYPKYGYRILRKQTSQIVKGWCGGHCSGCSP 4758
            PC   CG    +   +C   RD+Q  V    + A  P+P       +  CG      W              SC + CG GK     +C    +Q        TV+ + C   D  D P  E  C +  C  L   Y K    PI+   T    +   + N  L        R+ G P               ++W T PW  CS++C    Q+R+V C          DE           + CD  + KPI +R C   SC  W     G+CS KCG G R +   C++    N ++   +D  C  + L KP D R +C +  C  E+ W    W+ CSVSCG G++ R + C    E  T+      E CK+   P   + C+   CPKW   EW +C  TC  G Q R V C    ++++  +S+C    + P+ Q C +++   + W   +W +CS +C  G++ R   C      K +  S C+ +  P E   C V+ C    F W+    SEC    C  G     V C       +Y +K     H  Y Y    N    R        +N        +P   ++C   +  R V C+ +        MC    KP+  R+C       ++PR+C E+K  + V  DGE+ + I       IYCA M +E PKEY+TL      NY+    Y   + + C Y      + +C   K +      + ++K+R+++  L I   D  F+ T     +PF TA DC  +  CP+G F INL GTG S+S   +W          I +      V G CGG+C  C P
Sbjct: 1146 PCSATCGKGTRMRYVSC---RDDQGSVADEAACAQLPKPLATEACSVTPCGQWKALEW-------------SSCSVTCGQGKATRQVICVDFADQ--------TVDGSEC---DPDDVPAVEQECSMSPCYYLNHDYSK----PIQ---TVPNTDHRIRSNPTLAI----LNRNTGRPAGS----------GGSQWRTGPWGACSSTCAGGFQRRVVVC---------QDENGYPA------SNCDEKT-KPIEQRSCESGSCPQWAFGNWGECSKKCGGGTRTRQVVCQRS---NGDIF--NDLSC--EILDKPPD-REQCNMHSCPRETGWNSGPWNVCSVSCGRGVKTRPVYC-VTKEGVTVEP----ENCKHLAKPNIQKKCRGGKCPKWKAGEWEKCSVTCGRGIQQRAVHC-QVGAQKMSRESECPQHARPPSEQYCQVAECPLYTWKAEEWQECSKTCDEGLRYRKAIC-LDEDKKEVPQSHCEENKKPPEVEKCNVQSCE---FLWITGEWSEC-SVTCGTGYKQRLVTCSE-----VYSAK----DHYEYGYQSSANCPFPREKCGVIFLENDVKSAVLLVPSCSVTCGSGVTQRSVQCLTN--EDLPSNMCSVDQKPEEKRIC-------DLPRNCLEVKRLKHVGADGEHYVMIQEK-IIKIYCAGMQSESPKEYITLLSGEAENYSEVYGYRLQNPTECPYNGSRREDCQC---KKDYTAAGFSTFSKVRLDVVTLQIITTDLHFARTQDGRPVPFATAGDCYSAAKCPQGRFSINLLGTGLSISETAKWMSQGNYAVTEIKKSPDGTKVTGRCGGYCGKCVP 1875

HSP 3 Score: 133.265 bits (334), Expect = 2.075e-30
Identity = 125/494 (25.30%), Postives = 188/494 (38.06%), Query Frame = 1 
Query: 2701 WSYGKWEECPIECGTTFRYRNFICKDNKGLEWQKEWCERHLGLPDNKETCLSFNNCRNLTRWVTSPWSRCSNSCESELQKRMVYCFRSEKSDEILDEKFLKIHEQISDAFCDIHSPKPITERPCSLNSCYFWIXXXXXXXXXXXXLGFRIQSHECKKKF----NKNHEMITVDDKFCLKQNLVKPLDVRMRCFLKKCAIESFWIEMEWSKCSVSCGEGLQYRSLKCGYENENKTLTTWDNNEMCKNKMVPVSIQICKVTPCPKWIYSEWSECEGTCEYGSQHRTVLCTDPISEQILPDSKCDIKNKFPNFQKCLLSKLCGH--WIVGKWSQCSASCGLGVKTRTITCNYSNGSKSIDHSVCKSVA-PFEEIHCQVKPCSTNAFWWLVKPSECYEYNCQPGIMYAHVRCVNRKFQVLYDSKCSRIKHPSYYVGCLNTTCRRYFWTAESWDNIPCPDISCTMKIRNRDVYCVDDYGNIQKDAMCDQSDKPDTWRLC 4161
            W +G W  C   CG   R R   C+D++G    +  C + L  P   E C S   C    +W    WS CS +C      R V C   + +D+ +D            + CD     P  E+ CS++ CY+                    +H+  K      N +H + +      L +N  +P            +  S W    W  CS +C  G Q R + C  EN             C  K  P+  + C+   CP+W +  W EC   C  G++ R V+C     + I  D  C+I +K P+ ++C +        W  G W+ CS SCG GVKTR + C    G  +++   CK +A P  +  C+   C      W     E     C  GI    V C     ++  +S+C +   P     C    C  Y W AE W        +C   +R R   C+D+       + C+++ KP     C
Sbjct: 1139 WRFGSWTPCSATCGKGTRMRYVSCRDDQGSVADEAACAQ-LPKPLATEAC-SVTPC---GQWKALEWSSCSVTCGQGKATRQVICV--DFADQTVD-----------GSECDPDD-VPAVEQECSMSPCYYL-------------------NHDYSKPIQTVPNTDHRIRSNPTLAILNRNTGRPAG----------SGGSQWRTGPWGACSSTCAGGFQRRVVVCQDENGYPASN-------CDEKTKPIEQRSCESGSCPQWAFGNWGECSKKCGGGTRTRQVVCQRSNGD-IFNDLSCEILDKPPDREQCNMHSCPRETGWNSGPWNVCSVSCGRGVKTRPVYCVTKEGV-TVEPENCKHLAKPNIQKKCRGGKCPK----WKAGEWEKCSVTCGRGIQQRAVHCQVGAQKMSRESECPQHARPPSEQYCQVAECPLYTWKAEEWQEC---SKTCDEGLRYRKAICLDEDKKEVPQSHCEENKKPPEVEKC 1568

HSP 4 Score: 58.151 bits (139), Expect = 1.466e-7
Identity = 60/238 (25.21%), Postives = 100/238 (42.02%), Query Frame = 1 
Query: 3484 YSEWSECEGTCEYGSQHRTVLCTDPISEQILPDSKCD-IKNKFPNFQKCLLSKLCGHWIVGKWSQCSASCGLGVKTRTITC----NYSNGSKSIDHSVCKSVA-PFEEIHCQVKPCSTNAFWWLVKP-SECYEYNCQPGIMYAHVRCVNRKFQVLYDSKCSRIKHPSYYVGCLNTTCRRYFWTAESWDNIPCPDISCTMKIRNRDVYCVDDYGNIQ-KDAMCDQSDKPDTWRLCPSPQ 4173
            Y  W  C   C+ G + +  +C     + ++ D +CD I    P  + C  ++    W V + S+C+  CGLG +T  I C         ++ +D   C  +  P  +  C    C+T    W   P SEC + +C  G       CVN    +L DSKC + + P+    C    C +  W    W +     ++C    ++R  +C   +G+ +  D  CD   KP++   C  P+
Sbjct:  842 YGPWQPCNKMCQ-GERKQKPVCIRDSDQLVVSDQRCDRIPQPEPVTEPCN-TECEVRWHVARKSECTVQCGLGYRTLDIHCAKYTRADGKNEKVDERYCSHLQKPLTKEKCSGD-CNTGG--WRYSPWSECSK-SCGTGTRRRRAICVNALHDILDDSKCGQQEKPTEQR-CSEFPCPQ--WKTGDWSDCL---VTCGKGHKHRQTWC--QFGDDRLHDRFCDTETKPESVEACEQPE 1065
[Close]
BLAST of A disintegrin and metalloproteinase with thrombospondin motifs vs. Ensembl Xenopus
Match: ADAMTS9 (ADAM metallopeptidase with thrombospondin type 1 motif 9 [Source:NCBI gene;Acc:493280])

HSP 1 Score: 381.333 bits (978), Expect = 2.807e-107
Identity = 348/1384 (25.14%), Postives = 538/1384 (38.87%), Query Frame = 1 
Query:  397 LNKPLFSCKLLKNNGYRNIPQESHFSRVFQRMKRETYPVVDSEIVEPNIIELLIVVTSNFVKRFKKDFRQYILSNVAIATKLLHDPTIKASITXXXXXXXXXXEDYERNNDLHDWSLLSQDRVVSRFCHWVRQKKQLWN---YSWDSAILIND-----GVFSSNAIGIAHLRSMCND-NNCLAVVDRGFGTGFIIAHELAHQMNARHDFDNAEACSFFEKQYDNKTKYNTIMSTSLFFEYYPFIWSVCSQNVINSFLKSKYSFCLKQRNRHRNLYPHEQINEFFQKYSTGVDYDLNEQCSFAFGEKSEFCETDQNSRKKCSVLYC--RLKRYPICLRADAIIADGTECDVNQHCINGKCLYKNITIAPIDGGWSEYSEWSNCSRPCNGGVQFSYRTCDNPVPADGGRFCTGTKERIRSCNIEECSSFS-DPREESCGKYNLKPY----IPTNDEEFP----------CNLVCITTNHSLKYDI--SLTDGTPCSPFRSDICVKGTCYKTGCDRIVGSKKAIDNCNICAGQNDTCFKKESFFDGSKVAKVRMIRAFRIPPNVYNLFIKKVSQRMTPFTDE--VYDDFELLLVVNRRTVIRRSETIEPLAGGQLRYSGSKNKVETISIKGKLNVGISI-VIKVEN-----TKTTLNLPFIS--YHYFVKDIFVWKYLEVITHPCKDQCGGFIEISPACFKKRDNQRYVDHYCSKATKPEPKIIKCGAICGYRWQRATEHYINSTVNKSCPIRCGTGKVKIPFVCQKINNQDDNNSLWETVEENLCFAVDLVDRPIEELNCVGQCNPLLWSYGKWEECPIECGTTFRYRNFICKD------------------------------------------NKGLEWQKEWCE-----RHLGLPDNKETCLSFNNCRN--LTRWVTSPWSRCSNSCESELQKRMVYCFRSEKSDEILDEKFLKIHEQISDAFCDIHSPKPITERPCSLNSCYFWIXXXXXXXXXXXXLGFRIQSHECKKKFNKNHEMITVDDKFCLKQNLVKPLDVRMRCFLKKCAIESFWIEMEWSKCSVSCGEGLQYRSLKCGYENENKTLTTWDNNEMCKNKMVPVSIQICKVTPC------------------------------------------PKWIYSEWSECEGTCEYGSQHRTVLCTDPISEQILPDSKCDIKNKFPNFQKCLLSKLCGHWIVGKWSQCSASCGLGVKTRTITCNYSNGSKSIDHSVCKSVAPFEEIHCQVKPCSTNAFWWLVKPSECYEYNCQPGIMYAHVRCVNRKFQVLYDSKCSRIKHPSYYVGCLNTTCRRYFWTAESWDNIPCPDISCTMKIRNRDVYCVDDYGNIQKDAMCDQSDKPDTWRLC 4161
            LNK L    L   N   N    +  +R  +R KR         +  P  +E+++V  +  V+    + + Y+L+ ++I   +  DP+I   I I +V + ++ ++ E           +    +  FC W + +    +      D+A+LI            + +G+A L ++C+   +C    D G  T F IAHEL H  N  HD  N   C    K+   K + + +M+ +L F   P++WS CS+  +  FL + Y  CL      R     +Q+         G  Y++N+QC   FG  S+ C   Q    +C  L+C     ++  C       ADGTEC+  +HC  G C+ K   +   DG W  +S +  CSR C GG++ S R C+ P P +GG++C G + + +SCN E C+    D REE C  ++ K +    +P N    P          C L C     +  Y +   + DGT C P  +DICV+G C + GCD ++ SK   D C +C G N +C      ++   +         RIP    NL +++ S    P  D      +     ++N   V+   +    +    + YSGS N +E I+   ++   I + ++ V N      + T N+P       ++      W+       PC   C G  +  P C +  D     D  C +  +PEP    C   C  RW  A +          C ++CG G   +   C K    D  N   E V+E  C     + +P+ +  C G CN   W Y  W EC   CGT  R R  IC +                                           KG + ++ WC+      H    D +    S   C       W   PW +C+ +C    Q R+V C        + D +            C+  +   I E    ++S   W       CSA CG G R++   C     ++ +    D+  C +  L KPL     C +  C     W  +EWS CSV+CG+G   R + C  +  ++T+   D +E C    VP   Q C ++PC                                           +W    W  C  TC  G Q R V+C D   E   P S CD K K P  Q+   S  C  W  G W +CS  CG G +TR + C  SNG    D S      P +   C +  C      W   P      +C  G+    V CV ++   +    C  +  P+    C    C +  W A  W+      ++C   I+ R V+C      + +++ C Q  +P + + C
Sbjct:  193 LNKGL----LGTQNPLFNKADNATGTRTLRRKKRF--------LSYPRYVEVMVVADNKMVEYHGANLQHYVLTLMSIVASIYKDPSIGNLINIAIVKLAVVHDEQE-----GPAISFNAQSTLKNFCIWQQSQNNPDDNHPSHHDTAVLITRQDICRAQEKCDTLGLAELGTVCDPYRSCSISEDNGLSTAFTIAHELGHVFNMPHDDSNK--C----KEESGKNQQH-VMAPTLNFYTNPWMWSKCSRKYVTQFLDTGYGECLLDEPISRTYTLPQQL--------PGALYNVNKQCELIFGPGSQVCPYMQ---MQCRRLWCISSDGQHKGCRTQHTPWADGTECEPGKHCRYGVCIPKERDVQIADGSWGSWSPFGACSRSCGGGIKTSIRECNRPEPKNGGKYCVGRRMKFKSCNTELCAKHKRDFREEQCADFDGKHFNINGLPPNVRWVPKYSGILMKDRCKLFCRVAGSTAYYQLRDRVVDGTSCGPDTNDICVQGLCRQAGCDHVLNSKARRDKCGVCGGDNSSCKTIAGTYN---IVHYGYNSVVRIPAGATNLDVRQHSYSGKPEDDNYLALSNSHGEFLLNGDFVVSMFKREIKVGNAVIEYSGSDNAIERINCTDRIEQEIVLQILSVGNLYNPDVRYTFNIPIEDKPQQFYWNPYGPWQ-------PCNKMCQGERKQKPVCIRDSDQLVVSDQRCDRIPQPEPVTEPCNTECEVRWHVARK--------SECTVQCGLGYRTLDIHCAKYTRADGKN---EKVDERYC---SHLQKPLTKEKCSGDCNTGGWRYSPWSECSKSCGTGTRRRRAICVNALHDILDDSKCGQQEKPTEQRCSEFPCPQWKTGDWSDCLVTCGKGHKHRQTWCQFGDDRLHDRFCDTETKPESVEACEQPECASWQVGPWGQCTAACGPGYQMRVVKCVVGAYRAVVDDSECNAATRPTDTQDCEADACPGIPETKQIVHSRTQWRFGSWTPCSATCGKGTRMRYVSC-----RDDQGSVADEAACAQ--LPKPLATEA-CSVTPCGQ---WKALEWSSCSVTCGQGKATRQVIC-VDFADQTV---DGSE-CDPDDVPAVEQECSMSPCYYLNHDYSKPIQTVPNTDHRIRSNPTLAILNRNTGRPAGSGGSQWRTGPWGACSSTCAGGFQRRVVVCQD---ENGYPASNCDEKTK-PIEQRSCESGSCPQWAFGNWGECSKKCGGGTRTRQVVCQRSNGDIFNDLSCEILDKPPDREQCNMHSCPRETG-WNSGPWNVCSVSCGRGVKTRPVYCVTKEGVTVEPENCKHLAKPNIQKKCRGGKCPK--WKAGEWEKC---SVTCGRGIQQRAVHCQVGAQKMSRESECPQHARPPSEQYC 1491

HSP 2 Score: 203.756 bits (517), Expect = 6.190e-52
Identity = 231/835 (27.66%), Postives = 339/835 (40.60%), Query Frame = 1 
Query: 2323 PCKDQCGGFIEIS-PACFKKRDNQRYVDHYCSKATKPEP------KIIKCGAICGYRWQRATEHYINSTVNKSCPIRCGTGKVKIPFVCQKINNQDDNNSLWETVEENLCFAVDLVDRPIEELNC-VGQCNPLLWSYGKWEECPIECGTTFRYRNFICKDNKGLEWQKEWCERHLGLPDNKETCLSFNNCRNLTRWVTSPWSRCSNSCESELQKRMVYCFRSEKSDEILDEKFLKIHEQISDAFCDIHSPKPITERPCSLNSCYFWIXXXXXXXXXXXXLGFRIQSHECKKKFNKNHEMITVDDKFCLKQNLVKPLDVRMRCFLKKCAIESFWIEMEWSKCSVSCGEGLQYRSLKCGYENENKTLTTWDNNEMCKNKMVPVSIQICKVTPCPKWIYSEWSECEGTCEYGSQHRTVLCTDPISEQILPDSKCDIKNKFPNFQKCLLSKLCGH-WIVGKWSQCSASCGLGVKTRTITCNYSNGSKSIDHSVCK-SVAPFEEIHCQVKPCSTNAFWWLVKP-SECYEYNCQPGIMYAHVRCVNRKFQVLYDSKCSRIKHPSY-YVGCLNTTCRRYFWTAESWDN--------IPCPDISCTMKIRNRDVYCVDDYGNIQKDAMCDQSDKPDTWRLCPSPQNCSNIPRSCKELKSRQSVSKDGEYSLAIDLNWAYFIYCADMNTEEPKEYLTL---RELNYARTSKYVSTDVSSCIYEEEMEFNQKCPTCKINENLWSITYYNKIRINLSDLSIDVMDDRFSATNGQSFIPFGTAKDCAGSTSCPKGHFKINLRGTGFSVSMETRWNEVYPKYGYRILRKQTSQIVKGWCGGHCSGCSP 4758
            PC   CG    +   +C   RD+Q  V    + A  P+P       +  CG      W              SC + CG GK     +C    +Q        TV+ + C   D  D P  E  C +  C  L   Y K    PI+   T    +   + N  L        R+ G P               ++W T PW  CS++C    Q+R+V C          DE           + CD  + KPI +R C   SC  W     G+CS KCG G R +   C++    N ++   +D  C  + L KP D R +C +  C  E+ W    W+ CSVSCG G++ R + C    E  T+      E CK+   P   + C+   CPKW   EW +C  TC  G Q R V C    ++++  +S+C    + P+ Q C +++   + W   +W +CS +C  G++ R   C      K +  S C+ +  P E   C V+ C    F W+    SEC    C  G     V C       +Y +K     H  Y Y    N    R        +N        +P   ++C   +  R V C+ +        MC    KP+  R+C       ++PR+C E+K  + V  DGE+ + I       IYCA M +E PKEY+TL      NY+    Y   + + C Y      + +C   K +      + ++K+R+++  L I   D  F+ T     +PF TA DC  +  CP+G F INL GTG S+S   +W          I +      V G CGG+C  C P
Sbjct: 1127 PCSATCGKGTRMRYVSC---RDDQGSVADEAACAQLPKPLATEACSVTPCGQWKALEW-------------SSCSVTCGQGKATRQVICVDFADQ--------TVDGSEC---DPDDVPAVEQECSMSPCYYLNHDYSK----PIQ---TVPNTDHRIRSNPTLAI----LNRNTGRPAGS----------GGSQWRTGPWGACSSTCAGGFQRRVVVC---------QDENGYPA------SNCDEKT-KPIEQRSCESGSCPQWAFGNWGECSKKCGGGTRTRQVVCQRS---NGDIF--NDLSC--EILDKPPD-REQCNMHSCPRETGWNSGPWNVCSVSCGRGVKTRPVYC-VTKEGVTVEP----ENCKHLAKPNIQKKCRGGKCPKWKAGEWEKCSVTCGRGIQQRAVHC-QVGAQKMSRESECPQHARPPSEQYCQVAECPLYTWKAEEWQECSKTCDEGLRYRKAIC-LDEDKKEVPQSHCEENKKPPEVEKCNVQSCE---FLWITGEWSEC-SVTCGTGYKQRLVTCSE-----VYSAK----DHYEYGYQSSANCPFPREKCGVIFLENDVKSAVLLVPSCSVTCGSGVTQRSVQCLTN--EDLPSNMCSVDQKPEEKRIC-------DLPRNCLEVKRLKHVGADGEHYVMIQEK-IIKIYCAGMQSESPKEYITLLSGEAENYSEVYGYRLQNPTECPYNGSRREDCQC---KKDYTAAGFSTFSKVRLDVVTLQIITTDLHFARTQDGRPVPFATAGDCYSAAKCPQGRFSINLLGTGLSISETAKWMSQGNYAVTEIKKSPDGTKVTGRCGGYCGKCVP 1856

HSP 3 Score: 133.265 bits (334), Expect = 2.466e-30
Identity = 125/490 (25.51%), Postives = 185/490 (37.76%), Query Frame = 1 
Query: 2701 WSYGKWEECPIECGTTFRYRNFICKDNKGLEWQKEWCERHLGLPDNKETCLSFNNCRNLTRWVTSPWSRCSNSCESELQKRMVYCFRSEKSDEILDEKFLKIHEQISDAFCDIHSPKPITERPCSLNSCYFWIXXXXXXXXXXXXLGFRIQSHECKKKFNKNHEMITVDDKFCLKQNLVKPLDVRMRCFLKKCAIESFWIEMEWSKCSVSCGEGLQYRSLKCGYENENKTLTTWDNNEMCKNKMVPVSIQICKVTPCPKWIYSEWSECEGTCEYGSQHRTVLCTDPISEQILPDSKCDIKNKFPNFQKCLLSKLCGH--WIVGKWSQCSASCGLGVKTRTITCNYSNGSKSIDHSVCKSVA-PFEEIHCQVKPCSTNAFWWLVKPSECYEYNCQPGIMYAHVRCVNRKFQVLYDSKCSRIKHPSYYVGCLNTTCRRYFWTAESWDNIPCPDISCTMKIRNRDVYCVDDYGNIQKDAMCDQSDKPDTWRLC 4161
            W +G W  C   CG   R R   C+D++G    +  C + L  P   E C S   C    +W    WS CS +C      R V C   + +D+ +D            + CD     P  E+ CS++ CY+     S           RI+S+      N+N                 +P            +  S W    W  CS +C  G Q R + C  EN             C  K  P+  + C+   CP+W +  W EC   C  G++ R V+C     + I  D  C+I +K P+ ++C +        W  G W+ CS SCG GVKTR + C    G  +++   CK +A P  +  C+   C      W     E     C  GI    V C     ++  +S+C +   P     C    C  Y W AE W        +C   +R R   C+D+       + C+++ KP     C
Sbjct: 1120 WRFGSWTPCSATCGKGTRMRYVSCRDDQGSVADEAACAQ-LPKPLATEAC-SVTPC---GQWKALEWSSCSVTCGQGKATRQVICV--DFADQTVD-----------GSECDPDD-VPAVEQECSMSPCYYLNHDYSKPIQTVPNTDHRIRSNPTLAILNRN---------------TGRPAG----------SGGSQWRTGPWGACSSTCAGGFQRRVVVCQDENGYPASN-------CDEKTKPIEQRSCESGSCPQWAFGNWGECSKKCGGGTRTRQVVCQRSNGD-IFNDLSCEILDKPPDREQCNMHSCPRETGWNSGPWNVCSVSCGRGVKTRPVYCVTKEGV-TVEPENCKHLAKPNIQKKCRGGKCPK----WKAGEWEKCSVTCGRGIQQRAVHCQVGAQKMSRESECPQHARPPSEQYCQVAECPLYTWKAEEWQEC---SKTCDEGLRYRKAICLDEDKKEVPQSHCEENKKPPEVEKC 1549

HSP 4 Score: 58.151 bits (139), Expect = 1.552e-7
Identity = 60/238 (25.21%), Postives = 100/238 (42.02%), Query Frame = 1 
Query: 3484 YSEWSECEGTCEYGSQHRTVLCTDPISEQILPDSKCD-IKNKFPNFQKCLLSKLCGHWIVGKWSQCSASCGLGVKTRTITC----NYSNGSKSIDHSVCKSVA-PFEEIHCQVKPCSTNAFWWLVKP-SECYEYNCQPGIMYAHVRCVNRKFQVLYDSKCSRIKHPSYYVGCLNTTCRRYFWTAESWDNIPCPDISCTMKIRNRDVYCVDDYGNIQ-KDAMCDQSDKPDTWRLCPSPQ 4173
            Y  W  C   C+ G + +  +C     + ++ D +CD I    P  + C  ++    W V + S+C+  CGLG +T  I C         ++ +D   C  +  P  +  C    C+T    W   P SEC + +C  G       CVN    +L DSKC + + P+    C    C +  W    W +     ++C    ++R  +C   +G+ +  D  CD   KP++   C  P+
Sbjct:  823 YGPWQPCNKMCQ-GERKQKPVCIRDSDQLVVSDQRCDRIPQPEPVTEPCN-TECEVRWHVARKSECTVQCGLGYRTLDIHCAKYTRADGKNEKVDERYCSHLQKPLTKEKCSGD-CNTGG--WRYSPWSECSK-SCGTGTRRRRAICVNALHDILDDSKCGQQEKPTEQR-CSEFPCPQ--WKTGDWSDCL---VTCGKGHKHRQTWC--QFGDDRLHDRFCDTETKPESVEACEQPE 1046
[Close]
BLAST of A disintegrin and metalloproteinase with thrombospondin motifs vs. Ensembl Xenopus
Match: ADAMTS9 (ADAM metallopeptidase with thrombospondin type 1 motif 9 [Source:NCBI gene;Acc:493280])

HSP 1 Score: 379.022 bits (972), Expect = 1.186e-106
Identity = 348/1384 (25.14%), Postives = 537/1384 (38.80%), Query Frame = 1 
Query:  397 LNKPLFSCKLLKNNGYRNIPQESHFSRVFQRMKRETYPVVDSEIVEPNIIELLIVVTSNFVKRFKKDFRQYILSNVAIATKLLHDPTIKASITXXXXXXXXXXEDYERNNDLHDWSLLSQDRVVSRFCHWVRQKKQLWN---YSWDSAILIND-----GVFSSNAIGIAHLRSMCND-NNCLAVVDRGFGTGFIIAHELAHQMNARHDFDNAEACSFFEKQYDNKTKYNTIMSTSLFFEYYPFIWSVCSQNVINSFLKSKYSFCLKQRNRHRNLYPHEQINEFFQKYSTGVDYDLNEQCSFAFGEKSEFCETDQNSRKKCSVLYC--RLKRYPICLRADAIIADGTECDVNQHCINGKCLYKNITIAPIDGGWSEYSEWSNCSRPCNGGVQFSYRTCDNPVPADGGRFCTGTKERIRSCNIEECSSFS-DPREESCGKYNLKPY----IPTNDEEFP----------CNLVCITTNHSLKYDI--SLTDGTPCSPFRSDICVKGTCYKTGCDRIVGSKKAIDNCNICAGQNDTCFKKESFFDGSKVAKVRMIRAFRIPPNVYNLFIKKVSQRMTPFTDE--VYDDFELLLVVNRRTVIRRSETIEPLAGGQLRYSGSKNKVETISIKGKLNVGISIVIKVEN-----TKTTLNLPF--ISYHYFVKDIFVWKYLEVITHPCKDQCGGFIEIS-PACFKKRDNQRYVDHYCSKATKPEPKIIKCGAICGYRWQRATEHYINSTVNKSCPIRCGTGKVKIPFVCQKINNQDDNNSLWETVEENLCFAVDLVDRPIEELNCVGQCNPLLWSYGKWEECPIECGTTFRYRNFICKD------------------------------------------NKGLEWQKEWCE-----RHLGLPDNKETCLSFNNCRN--LTRWVTSPWSRCSNSCESELQKRMVYCFRSEKSDEILDEKFLKIHEQISDAFCDIHSPKPITERPCSLNSCYFWIXXXXXXXXXXXXLGFRIQSHECKKKFNKNHEMITVDDKFCLKQNLVKPLDVRMRCFLKKCAIESFWIEMEWSKCSVSCGEGLQYRSLKCGYENENKTLTTWDNNEMCKNKMVPVSIQICKVTPC------------------------------------------PKWIYSEWSECEGTCEYGSQHRTVLCTDPISEQILPDSKCDIKNKFPNFQKCLLSKLCGHWIVGKWSQCSASCGLGVKTRTITCNYSNGSKSIDHSVCKSVAPFEEIHCQVKPCSTNAFWWLVKPSECYEYNCQPGIMYAHVRCVNRKFQVLYDSKCSRIKHPSYYVGCLNTTCRRYFWTAESWDNIPCPDISCTMKIRNRDVYCVDDYGNIQKDAMCDQSDKPDTWRLC 4161
            LNK L    L   N   N    +  +R  +R KR         +  P  +E+++V  +  V+    + + Y+L+ ++I   +  DP+I   I I +V + ++ ++ E           +    +  FC W + +    +      D+A+LI            + +G+A L ++C+   +C    D G  T F IAHEL H  N  HD  N   C    K+   K + + +M+ +L F   P++WS CS+  +  FL + Y  CL      R     +Q+         G  Y++N+QC   FG  S+ C         C  L+C     ++  C       ADGTEC+  +HC  G C+ K   +   DG W  +S +  CSR C GG++ S R C+ P P +GG++C G + + +SCN E C+    D REE C  ++ K +    +P N    P          C L C     +  Y +   + DGT C P  +DICV+G C + GCD ++ SK   D C +C G N +C      ++   +         RIP    NL +++ S    P  D      +     ++N   V+   +    +    + YSGS N +E I+   ++     I++ V N      + T N+P       ++      W+       PC   C G I+ + P C +  D     D  C +  +PEP    C   C  RW  A +          C ++CG G   +   C K    D  N   E V+E  C     + +P+ +  C G CN   W Y  W EC   CGT  R R  IC +                                           KG + ++ WC+      H    D +    S   C       W   PW +C+ +C    Q R+V C        + D +            C+  +   I E    ++S   W       CSA CG G R++   C     ++ +    D+  C +  L KPL     C +  C     W  +EWS CSV+CG+G   R + C  +  ++T+   D +E C    VP   Q C ++PC                                           +W    W  C  TC  G Q R V+C D   E   P S CD K K P  Q+   S  C  W  G W +CS  CG G +TR + C  SNG    D S      P +   C +  C      W   P      +C  G+    V CV ++   +    C  +  P+    C    C +  W A  W+      ++C   I+ R V+C      + +++ C Q  +P + + C
Sbjct:  171 LNKGL----LGTQNPLFNKADNATGTRTLRRKKRF--------LSYPRYVEVMVVADNKMVEYHGANLQHYVLTLMSIVASIYKDPSIGNLINIAIVKLAVVHDEQE-----GPAISFNAQSTLKNFCIWQQSQNNPDDNHPSHHDTAVLITRQDICRAQEKCDTLGLAELGTVCDPYRSCSISEDNGLSTAFTIAHELGHVFNMPHDDSNK--C----KEESGKNQQH-VMAPTLNFYTNPWMWSKCSRKYVTQFLDTGYGECLLDEPISRTYTLPQQL--------PGALYNVNKQCELIFGPGSQVCPY------MCRRLWCISSDGQHKGCRTQHTPWADGTECEPGKHCRYGVCIPKERDVQIADGSWGSWSPFGACSRSCGGGIKTSIRECNRPEPKNGGKYCVGRRMKFKSCNTELCAKHKRDFREEQCADFDGKHFNINGLPPNVRWVPKYSGILMKDRCKLFCRVAGSTAYYQLRDRVVDGTSCGPDTNDICVQGLCRQAGCDHVLNSKARRDKCGVCGGDNSSCKTIAGTYN---IVHYGYNSVVRIPAGATNLDVRQHSYSGKPEDDNYLALSNSHGEFLLNGDFVVSMFKREIKVGNAVIEYSGSDNAIERINCTDRIEQ--EIILSVGNLYNPDVRYTFNIPIEDKPQQFYWNPYGPWQ-------PCNKMCQGTIQCNKPVCIRDSDQLVVSDQRCDRIPQPEPVTEPCNTECEVRWHVARK--------SECTVQCGLGYRTLDIHCAKYTRADGKN---EKVDERYC---SHLQKPLTKEKCSGDCNTGGWRYSPWSECSKSCGTGTRRRRAICVNALHDILDDSKCGQQEKPTEQRCSEFPCPQWKTGDWSDCLVTCGKGHKHRQTWCQFGDDRLHDRFCDTETKPESVEACEQPECASWQVGPWGQCTAACGPGYQMRVVKCVVGAYRAVVDDSECNAATRPTDTQDCEADACPGIPETKQIVHSRTQWRFGSWTPCSATCGKGTRMRYVSC-----RDDQGSVADEAACAQ--LPKPLATEA-CSVTPCGQ---WKALEWSSCSVTCGQGKATRQVIC-VDFADQTV---DGSE-CDPDDVPAVEQECSMSPCYYLNHDYSKPIQTVPNTDHRIRSNPTLAILNRNTGRPAGSGGSQWRTGPWGACSSTCAGGFQRRVVVCQD---ENGYPASNCDEKTK-PIEQRSCESGSCPQWAFGNWGECSKKCGGGTRTRQVVCQRSNGDIFNDLSCEILDKPPDREQCNMHSCPRETG-WNSGPWNVCSVSCGRGVKTRPVYCVTKEGVTVEPENCKHLAKPNIQKKCRGGKCPK--WKAGEWEKC---SVTCGRGIQQRAVHCQVGAQKMSRESECPQHARPPSEQYC 1464

HSP 2 Score: 184.111 bits (466), Expect = 6.130e-46
Identity = 188/739 (25.44%), Postives = 277/739 (37.48%), Query Frame = 1 
Query: 2701 WSYGKWEECPIECGTTFRYRNFICKDNKGLEWQKEWCERHLGLPDNKETCLSFNNCRNLTRWVTSPWSRCSNSCESELQKRMVYCFRSEKSDEILDEKFLKIHEQISDAFCDIHSPKPITERPCSLNSCYFWIXXXXXXXXXXXXLGFRIQSHECKKKFNKN------------------------------HEMITVDDKFCLKQNL---VKPLDVRMRCFLKKCAIESFWIEMEWSKCSVSCGEGLQYRSLKCGYENENKTLTTWDNNEMCKNKMVPVSIQICKVTPCPK---WIYSEWSECEGTCEYGSQHRTVLCTDPISEQILPDSKCDIKNKFPNFQKCLLSKLCGHWIVGKWSQCSASCGLGVKTRTITCNYSNGSKSIDHSVCKSVAPFEEIHCQVKPCSTNAF----WWLVKPS---ECYEYNCQPGIMYAHVRC-----VNRKFQVLYDSKCS-RIKHPSYYVGCLNTTCR-RYFWTAESWDNIPCPDISCTMKIRNRDVYCVDDYGNIQKDAMCDQSDKPDTWRLCPSPQNCSNIPRSCKELKSRQSVSKDGEYSLAIDLNWAYFIYCADMNTEEPKEYLTL---RELNYARTSKYVSTDVSSCIYEEEMEFNQKCPTCKINENLWSITYYNKIRINLSDLSIDVMDDRFSATNGQSFIPFGTAKDCAGSTSCPKGHFKINLRGTGFSVSMETRWNEVYPKYGYRILRKQTSQIVKGWCGGHCSGCSP 4758
            W +G W  C   CG   R R   C+D++G    +  C + L  P   E C S   C    +W    WS CS +C      R V C   + +D+ +D            + CD     P  E+ CS++ CY+     S           RI+S+      N+N                                ++  D+      N     KP++ R  C    C     W    W +CS  CG G + R + C   N +       N+  C+    P   + C +  CP+   W    W+ C  +C  G + R V C       + P++ C    K PN QK      C  W  G+W +CS +CG G++ R + C       S +    +   P  E +CQV  C    +    W  V  S         C  G     V C         ++  Y S  +   + P     C    C     W   +W       ++C   +  R V C+ +        MC    KP+  R+C S  +C     SC +LK    V  DGE+ + I       IYCA M +E PKEY+TL      NY+    Y   + + C Y      + +C   K +      + ++K+R+++  L I   D  F+ T     +PF TA DC  +  CP+G F INL GTG S+S   +W          I +      V G CGG+C  C P
Sbjct: 1093 WRFGSWTPCSATCGKGTRMRYVSCRDDQGSVADEAACAQ-LPKPLATEAC-SVTPC---GQWKALEWSSCSVTCGQGKATRQVICV--DFADQTVD-----------GSECDPDD-VPAVEQECSMSPCYYLNHDYSKPIQTVPNTDHRIRSNPTLAILNRNTGRPAGSGGSQWRTGPWGACSSTCAGGFQRRVVVCQDENGYPASNCDEKTKPIEQR-SCESGSCPQ---WAFGNWGECSKKCGGGTRTRQVVCQRSNGDIF-----NDLSCEILDKPPDREQCNMHSCPRETGWNSGPWNVCSVSCGRGVKTRPVYCVTKEGVTVEPEN-CKHLAK-PNIQKKCRGGKCPKWKAGEWEKCSVTCGRGIQQRAVHCQVGAQKMSRESECPQHARPPSEQYCQVAECPLYTWKAEEWQEVSGSWEGRACSVTCGTGYKQRLVTCSEVYSAKDHYEYGYQSSANCPGEQPPTVQNCYQGECPISASWRVGNWGKC---SVTCGSGVTQRSVQCLTN--EDLPSNMCSVDQKPEEKRICYSNHDCKICFISCLKLKH---VGADGEHYVMIQEK-IIKIYCAGMQSESPKEYITLLSGEAENYSEVYGYRLQNPTECPYNGSRREDCQC---KKDYTAAGFSTFSKVRLDVVTLQIITTDLHFARTQDGRPVPFATAGDCYSAAKCPQGRFSINLLGTGLSISETAKWMSQGNYAVTEIKKSPDGTKVTGRCGGYCGKCVP 1789

HSP 3 Score: 105.531 bits (262), Expect = 6.393e-22
Identity = 131/525 (24.95%), Postives = 197/525 (37.52%), Query Frame = 1 
Query: 2323 PCKDQCGGFIEIS-PACFKKRDNQRYVDHYCSKATKPEP------KIIKCGAICGYRWQRATEHYINSTVNKSCPIRCGTGKVKIPFVCQKINNQ---------DDNNSLWETVEENLCFAVDL-VDRPIEELNCVG---QCNPLL-----------------WSYGKWEECPIECGTTFRYRNFICKDNKGLEWQKEWCERHLGLPDNKETCLSFNNCRNLTRWVTSPWSRCSNSCESELQKRMVYCFRSEKSDEILDEKFLKIHEQISDAFCDIHSPKPITERPCSLNSC---YFWIXXXXXXXXXXXXLGFRIQSHECKKKFNKNHEMITVDDKFCLKQNLVKPLDVRMRCFLKKCAIESFWIEMEWSKCSVSCGEGLQYRSLKCGYENENKTLTTWDNNEMCKNKMVPVSIQICKVTPCP--KWIYSEWSECEG---------TCEYGSQHRTVLCTDPIS-----EQILPDSKCDIKNKFPNFQKCLLSK--LCGHWIVGKWSQCSASCGLGVKTRTITC 3723
            PC   CG    +   +C   RD+Q  V    + A  P+P       +  CG      W              SC + CG GK     +C    +Q         DD  ++ +    + C+ ++    +PI+ +       + NP L                 W  G W  C   C   F+ R  +C+D  G  +    C+     P  + +C S     +  +W    W  CS  C    + R V C RS               +  +D  C+I    P  E+ C+++SC     W       CS  CG G + +   C  K     E +TV+ + C  ++L KP +++ +C   KC     W   EW KCSV+CG G+Q R++ C    +  +  +      C     P S Q C+V  CP   W   EW E  G         TC  G + R V C++  S     E     S      + P  Q C   +  +   W VG W +CS +CG GV  R++ C
Sbjct: 1100 PCSATCGKGTRMRYVSC---RDDQGSVADEAACAQLPKPLATEACSVTPCGQWKALEW-------------SSCSVTCGQGKATRQVICVDFADQTVDGSECDPDDVPAVEQECSMSPCYYLNHDYSKPIQTVPNTDHRIRSNPTLAILNRNTGRPAGSGGSQWRTGPWGACSSTCAGGFQRRVVVCQDENG--YPASNCDEKT-KPIEQRSCESG----SCPQWAFGNWGECSKKCGGGTRTRQVVCQRSNG-------------DIFNDLSCEILDKPPDREQ-CNMHSCPRETGWNSGPWNVCSVSCGRGVKTRPVYCVTK-----EGVTVEPENC--KHLAKP-NIQKKCRGGKCPK---WKAGEWEKCSVTCGRGIQQRAVHCQVGAQKMSRES-----ECPQHARPPSEQYCQVAECPLYTWKAEEWQEVSGSWEGRACSVTCGTGYKQRLVTCSEVYSAKDHYEYGYQSSANCPGEQPPTVQNCYQGECPISASWRVGNWGKCSVTCGSGVTQRSVQC 1571

HSP 4 Score: 79.7221 bits (195), Expect = 4.246e-14
Identity = 75/327 (22.94%), Postives = 128/327 (39.14%), Query Frame = 1 
Query: 2521 CPIRCGTGKVKIPFVCQKINNQDDNNSLWETVEENLCFAVDLVDRPIEELNCVGQCNP--LLWSYGKWEECPIECGTTFRYRNFICKDNKGLEWQKEWCERHLGLPDNKETCLSFNNCRNLTRWVTSPWSRCSNSCESELQKRMVYCFRSEKSDEILDEKFLKIHEQISDAFCDIHSPKPITERPCSLNSCYFWIXXXXXXXXXXXXLGFRIQSHECKKKFNKNHEMITVDDKFCLKQNLV------------KPLDVRMRCFLKKCAIESFWIEMEWSKCSVSCGEGLQYRSLKCGYENENKTLTTWD-NNEMCKNKMVPVSIQIC 3456
            C  +CG G      VCQ+ N    N+            + +++D+P +   C     P    W+ G W  C + CG   + R   C   +G+  + E C +HL  P+ ++ C          +W    W +CS +C   +Q+R V+C       ++  +K  +  E      C  H+ +P +E+ C +  C  +                R  S  C   + +   ++T  + +  K +              +P  V+  C+  +C I + W    W KCSV+CG G+  RS++C        LT  D  + MC     P   +IC
Sbjct: 1309 CSKKCGGGTRTRQVVCQRSNGDIFND-----------LSCEILDKPPDREQCNMHSCPRETGWNSGPWNVCSVSCGRGVKTRPVYCVTKEGVTVEPENC-KHLAKPNIQKKCRGGK----CPKWKAGEWEKCSVTCGRGIQQRAVHC-------QVGAQKMSRESE------CPQHA-RPPSEQYCQVAECPLYTWKAEEWQEVSGSWEGRACSVTCGTGYKQ--RLVTCSEVYSAKDHYEYGYQSSANCPGEQPPTVQ-NCYQGECPISASWRVGNWGKCSVTCGSGVTQRSVQC--------LTNEDLPSNMCSVDQKPEEKRIC 1594

HSP 5 Score: 57.7658 bits (138), Expect = 2.454e-7
Identity = 60/238 (25.21%), Postives = 98/238 (41.18%), Query Frame = 1 
Query: 3484 YSEWSECEGTCEYGSQHRTVLCTDPISEQILPDSKCD-IKNKFPNFQKCLLSKLCGHWIVGKWSQCSASCGLGVKTRTITC----NYSNGSKSIDHSVCKSVA-PFEEIHCQVKPCSTNAFWWLVKP-SECYEYNCQPGIMYAHVRCVNRKFQVLYDSKCSRIKHPSYYVGCLNTTCRRYFWTAESWDNIPCPDISCTMKIRNRDVYCVDDYGNIQ-KDAMCDQSDKPDTWRLCPSPQ 4173
            Y  W  C   C+   Q    +C     + ++ D +CD I    P  + C  ++    W V + S+C+  CGLG +T  I C         ++ +D   C  +  P  +  C    C+T    W   P SEC + +C  G       CVN    +L DSKC + + P+    C    C +  W    W +     ++C    ++R  +C   +G+ +  D  CD   KP++   C  P+
Sbjct:  795 YGPWQPCNKMCQGTIQCNKPVCIRDSDQLVVSDQRCDRIPQPEPVTEPCN-TECEVRWHVARKSECTVQCGLGYRTLDIHCAKYTRADGKNEKVDERYCSHLQKPLTKEKCSGD-CNTGG--WRYSPWSECSK-SCGTGTRRRRAICVNALHDILDDSKCGQQEKPTEQR-CSEFPCPQ--WKTGDWSDCL---VTCGKGHKHRQTWC--QFGDDRLHDRFCDTETKPESVEACEQPE 1019
[Close]
BLAST of A disintegrin and metalloproteinase with thrombospondin motifs vs. Ensembl Xenopus
Match: ADAMTS9 (ADAM metallopeptidase with thrombospondin type 1 motif 9 [Source:NCBI gene;Acc:493280])

HSP 1 Score: 378.252 bits (970), Expect = 2.274e-106
Identity = 352/1430 (24.62%), Postives = 552/1430 (38.60%), Query Frame = 1 
Query:  271 GVFQWDNKLWFIKPNTKTKFNSKFLKTEMNFLPHKIYF---TALNLNKPLFSCKLLKNNGYRNIPQESHFSRVFQRMKRETYPVVDSEIVEPNIIELLIVVTSNFVKRFKKDFRQYILSNVAIATKLLHDPTIKASITXXXXXXXXXXEDYERNNDLHDWSLLSQDRVVSRFCHWVRQKKQLWN---YSWDSAILIND-----GVFSSNAIGIAHLRSMCND-NNCLAVVDRGFGTGFIIAHELAHQMNARHDFDNAEACSFFEKQYDNKTKYNTIMSTSLFFEYYPFIWSVCSQNVINSFLKSKYSFCLKQRNRHRNLYPHEQINEFFQKYSTGVDYDLNEQCSFAFGEKSEFCETDQNSRKKCSVLYC--RLKRYPICLRADAIIADGTECDVNQHCINGKCLYKNITIAPIDGGWSEYSEWSNCSRPCNGGVQFSYRTCDNPVPADGGRFCTGTKERIRSCNIEECSSFS-DPREESCGKYNLKPY----IPTNDEEFP----------CNLVCITTNHSLKYDI--SLTDGTPCSPFRSDICVKGTCYKTGCDRIVGSKKAIDNCNICAGQNDTCFKKESFFDGSKVAKVRMIRAFRIPPNVYNLFIKKVSQRMTPFTDE--VYDDFELLLVVNRRTVIRRSETIEPLAGGQLRYSGSKNKVETISIKGKLNVGISI-VIKVEN-----TKTTLNLPF--ISYHYFVKDIFVWKYLEVITHPCKDQCGGFIEISPACFKKRDNQRYVDHYCSKATKPEPKIIKCGAICGYRWQRATEHYINSTVNKS-CPIRCGTGKVKIPFVCQKINNQDDNNSLWETVEENLCFAVDLVDRPIEELNCVGQCNPLLWSYGKWEECPIECGTTFRYRNFICKD------------------------------------------NKGLEWQKEWCE-----RHLGLPDNKETCLSFNNCRN--LTRWVTSPWSRCSNSCESELQKRMVYCFRSEKSDEILDEKFLKIHEQISDAFCDIHSPKPITERPCSLNSCYFWIXXXXXXXXXXXXLGFRIQSHECKKKFNKNHEMITVDDKFCLKQNLVKPLDVRMRCFLKKCAIESFWIEMEWSKCSVSCGEGLQYRSLKCGYENENKTLTTWDNNEMCKNKMVPVSIQICKVTPC------------------------------------------PKWIYSEWSECEGTCEYGSQHRTVLCTDPISEQILPDSKCDIKNKFPNFQKCLLSKLCGHWIVGKWSQCSASCGLGVKTRTITCNYSNGSKSIDHSVCKSVAPFEEIHCQVKPCSTNAFWWLVKPSECYEYNCQPGIMYAHVRCVNRKFQVLYDSKCSRIKHPSYYVGCLNTTCRRYFWTAESWDNIPCPDISCTMKIRNRDVYCVDDYGNIQKDAMCDQSDKPDTWRLC 4161
            G F+  +  +F++P      +      E +  PH +Y       N+++   +C    N G     Q   F++        T       +  P  +E+++V  +  V+    + + Y+L+ ++I   +  DP+I   I I +V + ++ ++ E           +    +  FC W + +    +      D+A+LI            + +G+A L ++C+   +C    D G  T F IAHEL H  N  HD  N   C    K+   K + + +M+ +L F   P++WS CS+  +  FL + Y  CL      R     +Q+         G  Y++N+QC   FG  S+ C         C  L+C     ++  C       ADGTEC+  +HC  G C+ K   +   DG W  +S +  CSR C GG++ S R C+ P P +GG++C G + + +SCN E C+    D REE C  ++ K +    +P N    P          C L C     +  Y +   + DGT C P  +DICV+G C + GCD ++ SK   D C +C G N +C      ++   +         RIP    NL +++ S    P  D      +     ++N   V+   +    +    + YSGS N +E I+   ++   I + ++ V N      + T N+P       ++      W+       PC   C G  +  P C +  D     D  C +  +PEP    C   C  R       Y+     KS C ++CG G   +   C K    D  N   E V+E  C     + +P+ +  C G CN   W Y  W EC   CGT  R R  IC +                                           KG + ++ WC+      H    D +    S   C       W   PW +C+ +C    Q R+V C        + D +            C+  +   I E    ++S   W       CSA CG G R++   C     ++ +    D+  C +  L KPL     C +  C     W  +EWS CSV+CG+G   R + C  +  ++T+   D +E C    VP   Q C ++PC                                           +W    W  C  TC  G Q R V+C D   E   P S CD K K P  Q+   S  C  W  G W +CS  CG G +TR + C  SNG    D S      P +   C +  C      W   P      +C  G+    V CV ++   +    C  +  P+    C    C +  W A  W+      ++C   I+ R V+C      + +++ C Q  +P + + C
Sbjct:  141 GTFKSQDGDYFVEP----LLSDDSEYEEEHNKPHVVYRHNPPHRNISREEQTCHTALNKGLLGT-QNPLFNKADNATGTRTLRRKKRFLSYPRYVEVMVVADNKMVEYHGANLQHYVLTLMSIVASIYKDPSIGNLINIAIVKLAVVHDEQEGPA-----ISFNAQSTLKNFCIWQQSQNNPDDNHPSHHDTAVLITRQDICRAQEKCDTLGLAELGTVCDPYRSCSISEDNGLSTAFTIAHELGHVFNMPHDDSNK--C----KEESGKNQQH-VMAPTLNFYTNPWMWSKCSRKYVTQFLDTGYGECLLDEPISRTYTLPQQL--------PGALYNVNKQCELIFGPGSQVCPY------MCRRLWCISSDGQHKGCRTQHTPWADGTECEPGKHCRYGVCIPKERDVQIADGSWGSWSPFGACSRSCGGGIKTSIRECNRPEPKNGGKYCVGRRMKFKSCNTELCAKHKRDFREEQCADFDGKHFNINGLPPNVRWVPKYSGILMKDRCKLFCRVAGSTAYYQLRDRVVDGTSCGPDTNDICVQGLCRQAGCDHVLNSKARRDKCGVCGGDNSSCKTIAGTYN---IVHYGYNSVVRIPAGATNLDVRQHSYSGKPEDDNYLALSNSHGEFLLNGDFVVSMFKREIKVGNAVIEYSGSDNAIERINCTDRIEQEIVLQILSVGNLYNPDVRYTFNIPIEDKPQQFYWNPYGPWQ-------PCNKMCQGERKQKPVCIRDSDQLVVSDQRCDRIPQPEPVTEPCNTECEVR-------YLWHVARKSECTVQCGLGYRTLDIHCAKYTRADGKN---EKVDERYC---SHLQKPLTKEKCSGDCNTGGWRYSPWSECSKSCGTGTRRRRAICVNALHDILDDSKCGQQEKPTEQRCSEFPCPQWKTGDWSDCLVTCGKGHKHRQTWCQFGDDRLHDRFCDTETKPESVEACEQPECASWQVGPWGQCTAACGPGYQMRVVKCVVGAYRAVVDDSECNAATRPTDTQDCEADACPGIPETKQIVHSRTQWRFGSWTPCSATCGKGTRMRYVSC-----RDDQGSVADEAACAQ--LPKPLATEA-CSVTPCGQ---WKALEWSSCSVTCGQGKATRQVIC-VDFADQTV---DGSE-CDPDDVPAVEQECSMSPCYYLNHDYSKPIQTVPNTDHRIRSNPTLAILNRNTGRPAGSGGSQWRTGPWGACSSTCAGGFQRRVVVCQD---ENGYPASNCDEKTK-PIEQRSCESGSCPQWAFGNWGECSKKCGGGTRTRQVVCQRSNGDIFNDLSCEILDKPPDREQCNMHSCPRETG-WNSGPWNVCSVSCGRGVKTRPVYCVTKEGVTVEPENCKHLAKPNIQKKCRGGKCPK--WKAGEWEKC---SVTCGRGIQQRAVHCQVGAQKMSRESECPQHARPPSEQYC 1490

HSP 2 Score: 177.178 bits (448), Expect = 9.820e-44
Identity = 186/741 (25.10%), Postives = 284/741 (38.33%), Query Frame = 1 
Query: 2701 WSYGKWEECPIECGTTFRYRNFICKDNKGLEWQKEWCERHLGLPDNKETCLSFNNCRNLTRWVTSPWSRCSNSCESELQKRMVYCFRSEKSDEILDEKFLKIHEQISDAFCDIHSPKPITERPCSLNSCYFWIXXXXXXXXXXXXLGFRIQSHECKKKFNKN------------------------------HEMITVDDKFCLKQNL---VKPLDVRMRCFLKKCAIESFWIEMEWSKCSVSCGEGLQYRSLKCGYENENKTLTTWDNNEMCKNKMVPVSIQICKVTPCPK---WIYSEWSECEGTCEYGSQHRTVLCTDPISEQILPDSKCDIKNKFPNFQKCLLSKLCGHWIVGKWSQCSASCGLGVKTRTITCNYSNGSKSIDHSVCKSVAPFEEIHCQVKPCSTNAF----WWLVKPSECYEYNCQPGIMY--------AHVRCVNRKFQVLYDSKCS-RIKHPSYYVGCLNTTCR-RYFWTAESWDNIPCPDISCTMKIRNRDVYCVDDYGNIQKDAMCDQSDKPDTWRLCPSPQNCSNIPRSCK-ELKSRQSVSKDGEYSLAIDLNWAYFIYCADMNTEEPKEYLTL---RELNYARTSKYVSTDVSSCIYEEEMEFNQKCPTCKINENLWSITYYNKIRINLSDLSIDVMDDRFSATNGQSFIPFGTAKDCAGSTSCPKGHFKINLRGTGFSVSMETRWNEVYPKYGYR-ILRKQTSQIVKGWCGGHCSGCSP 4758
            W +G W  C   CG   R R   C+D++G    +  C + L  P   E C S   C    +W    WS CS +C      R V C   + +D+ +D            + CD     P  E+ CS++ CY+     S           RI+S+      N+N                                ++  D+      N     KP++ R  C    C     W    W +CS  CG G + R + C   N +       N+  C+    P   + C +  CP+   W    W+ C  +C  G + R V C       + P++ C    K PN QK      C  W  G+W +CS +CG G++ R + C       S +    +   P  E +CQV  C    +    W  V  S  +E    PG ++        + V      ++  Y S  +   + P     C    C     W   +W       ++C   +  R V C+ +        MC    KP+  R+C S  +C    + C+  L S   V  D    +++ L + + IYCA M +E PKEY+TL      NY+    Y   + + C Y      + +C   K +      + ++K+R+++  L I   D  F+ T     +PF TA DC  +  CP+G F INL GTG S+S   +W     +  Y  +   Q    V G CGG+C  C P
Sbjct: 1119 WRFGSWTPCSATCGKGTRMRYVSCRDDQGSVADEAACAQ-LPKPLATEAC-SVTPC---GQWKALEWSSCSVTCGQGKATRQVICV--DFADQTVD-----------GSECDPDD-VPAVEQECSMSPCYYLNHDYSKPIQTVPNTDHRIRSNPTLAILNRNTGRPAGSGGSQWRTGPWGACSSTCAGGFQRRVVVCQDENGYPASNCDEKTKPIEQR-SCESGSCPQ---WAFGNWGECSKKCGGGTRTRQVVCQRSNGDIF-----NDLSCEILDKPPDREQCNMHSCPRETGWNSGPWNVCSVSCGRGVKTRPVYCVTKEGVTVEPEN-CKHLAK-PNIQKKCRGGKCPKWKAGEWEKCSVTCGRGIQQRAVHCQVGAQKMSRESECPQHARPPSEQYCQVAECPLYTWKAEEWQEVSGS--WEGRAAPGTIHNTHILVTCSEVYSAKDHYEYGYQSSANCPGEQPPTVQNCYQGECPISASWRVGNWGKC---SVTCGSGVTQRSVQCLTN--EDLPSNMCSVDQKPEEKRICYSNHDC----KICEFYLMSLFLVHCDWLEKVSVTLCY-WQIYCAGMQSESPKEYITLLSGEAENYSEVYGYRLQNPTECPYNGSRREDCQC---KKDYTAAGFSTFSKVRLDVVTLQIITTDLHFARTQDGRPVPFATAGDCYSAAKCPQGRFSINLLGTGLSISETAKW---MSQGNYAPVTSSQDGTKVTGRCGGYCGKCVP 1811

HSP 3 Score: 101.679 bits (252), Expect = 1.047e-20
Identity = 130/522 (24.90%), Postives = 196/522 (37.55%), Query Frame = 1 
Query: 2323 PCKDQCGGFIEISPACFKKRDNQRYVDHYCSKATKPEP------KIIKCGAICGYRWQRATEHYINSTVNKSCPIRCGTGKVKIPFVCQKINNQ---------DDNNSLWETVEENLCFAVDL-VDRPIEELNCVG---QCNPLL-----------------WSYGKWEECPIECGTTFRYRNFICKDNKGLEWQKEWCERHLGLPDNKETCLSFNNCRNLTRWVTSPWSRCSNSCESELQKRMVYCFRSEKSDEILDEKFLKIHEQISDAFCDIHSPKPITERPCSLNSC---YFWIXXXXXXXXXXXXLGFRIQSHECKKKFNKNHEMITVDDKFCLKQNLVKPLDVRMRCFLKKCAIESFWIEMEWSKCSVSCGEGLQYRSLKCGYENENKTLTTWDNNEMCKNKMVPVSIQICKVTPCP--KWIYSEWSECEGTCEY----GSQHRT---VLCTDPIS-----EQILPDSKCDIKNKFPNFQKCLLSK--LCGHWIVGKWSQCSASCGLGVKTRTITC 3723
            PC   CG    +       RD+Q  V    + A  P+P       +  CG      W              SC + CG GK     +C    +Q         DD  ++ +    + C+ ++    +PI+ +       + NP L                 W  G W  C   C   F+ R  +C+D  G  +    C+     P  + +C S     +  +W    W  CS  C    + R V C RS               +  +D  C+I    P  E+ C+++SC     W       CS  CG G + +   C  K     E +TV+ + C  ++L KP +++ +C   KC     W   EW KCSV+CG G+Q R++ C    +  +  +      C     P S Q C+V  CP   W   EW E  G+ E     G+ H T   V C++  S     E     S      + P  Q C   +  +   W VG W +CS +CG GV  R++ C
Sbjct: 1126 PCSATCGKGTRMR--YVSCRDDQGSVADEAACAQLPKPLATEACSVTPCGQWKALEW-------------SSCSVTCGQGKATRQVICVDFADQTVDGSECDPDDVPAVEQECSMSPCYYLNHDYSKPIQTVPNTDHRIRSNPTLAILNRNTGRPAGSGGSQWRTGPWGACSSTCAGGFQRRVVVCQDENG--YPASNCDEKT-KPIEQRSCESG----SCPQWAFGNWGECSKKCGGGTRTRQVVCQRSNG-------------DIFNDLSCEILDKPPDREQ-CNMHSCPRETGWNSGPWNVCSVSCGRGVKTRPVYCVTK-----EGVTVEPENC--KHLAKP-NIQKKCRGGKCPK---WKAGEWEKCSVTCGRGIQQRAVHCQVGAQKMSRES-----ECPQHARPPSEQYCQVAECPLYTWKAEEWQEVSGSWEGRAAPGTIHNTHILVTCSEVYSAKDHYEYGYQSSANCPGEQPPTVQNCYQGECPISASWRVGNWGKCSVTCGSGVTQRSVQC 1595

HSP 4 Score: 73.9442 bits (180), Expect = 2.557e-12
Identity = 92/378 (24.34%), Postives = 152/378 (40.21%), Query Frame = 1 
Query: 2518 SCPIRCGTGKVKIPFVCQKINNQDDNNSLWETVEENLCFAVDLVDRPIEELNCVGQCNPLLWSYGKWEECPIECGTTFRYRNFICKDNKGLEWQKEWCERHLGLPDNKETCLSFNNCRNLTRWVTSPWSRCSNSCESELQKRMVYCFRSEKSDEILDEKFLKIHEQISDAFCDIHSPKPITERPCSLNSCYFWIXXXXXXXXXXXXLGFRIQSHECK---KKFNKNHEMITVDDKFCLKQNLVKPLDVRMRCFLKKCAIESFWIEMEWSKCSVS----CGEGLQYRS---LKCG--YENENKTLTTWDNNEMCKNKMVPVSIQICKVTPCP---KWIYSEWSECEGTCEYGSQHRTVLCTDPISEQILPDSKCDIKNK 3606
            +C   C  G  +   VCQ  N    +N              D   +PIE+ +C     P  W++G W EC  +CG   R R  +C+ + G  +    CE  L  P ++E C + ++C   T W + PW+ CS SC   ++ R VYC   E     ++ +  K            H  KP  ++ C    C  W   +  KCS  CG G + ++  C+   +K ++  E           Q+   P +    C + +C + + W   EW + S S       G  + +   + C   Y  ++     + ++  C  +  P ++Q C    CP    W    W +C  TC  G   R+V C   ++ + LP + C +  K
Sbjct: 1280 ACSSTCAGGFQRRVVVCQDENGYPASN-------------CDEKTKPIEQRSCESGSCPQ-WAFGNWGECSKKCGGGTRTRQVVCQRSNGDIFNDLSCEI-LDKPPDREQC-NMHSCPRETGWNSGPWNVCSVSCGRGVKTRPVYCVTKEGV--TVEPENCK------------HLAKPNIQKKCRGGKCPKWKAGEWEKCSVTCGRGIQQRAVHCQVGAQKMSRESE---------CPQHARPPSE--QYCQVAECPLYT-WKAEEWQEVSGSWEGRAAPGTIHNTHILVTCSEVYSAKDHYEYGYQSSANCPGEQ-PPTVQNCYQGECPISASWRVGNWGKCSVTCGSGVTQRSVQC---LTNEDLPSNMCSVDQK 1611

HSP 5 Score: 57.3806 bits (137), Expect = 2.766e-7
Identity = 60/239 (25.10%), Postives = 100/239 (41.84%), Query Frame = 1 
Query: 3484 YSEWSECEGTCEYGSQHRTVLCTDPISEQILPDSKCD-IKNKFPNFQKCLLS-KLCGHWIVGKWSQCSASCGLGVKTRTITC----NYSNGSKSIDHSVCKSVA-PFEEIHCQVKPCSTNAFWWLVKP-SECYEYNCQPGIMYAHVRCVNRKFQVLYDSKCSRIKHPSYYVGCLNTTCRRYFWTAESWDNIPCPDISCTMKIRNRDVYCVDDYGNIQ-KDAMCDQSDKPDTWRLCPSPQ 4173
            Y  W  C   C+ G + +  +C     + ++ D +CD I    P  + C    ++   W V + S+C+  CGLG +T  I C         ++ +D   C  +  P  +  C    C+T    W   P SEC + +C  G       CVN    +L DSKC + + P+    C    C +  W    W +     ++C    ++R  +C   +G+ +  D  CD   KP++   C  P+
Sbjct:  820 YGPWQPCNKMCQ-GERKQKPVCIRDSDQLVVSDQRCDRIPQPEPVTEPCNTECEVRYLWHVARKSECTVQCGLGYRTLDIHCAKYTRADGKNEKVDERYCSHLQKPLTKEKCSGD-CNTGG--WRYSPWSECSK-SCGTGTRRRRAICVNALHDILDDSKCGQQEKPTEQR-CSEFPCPQ--WKTGDWSDCL---VTCGKGHKHRQTWC--QFGDDRLHDRFCDTETKPESVEACEQPE 1045
[Close]
BLAST of A disintegrin and metalloproteinase with thrombospondin motifs vs. Ensembl Mouse
Match: Adamts20 (a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 20 [Source:MGI Symbol;Acc:MGI:2660628])

HSP 1 Score: 374.785 bits (961), Expect = 3.279e-105
Identity = 356/1421 (25.05%), Postives = 560/1421 (39.41%), Query Frame = 1 
Query:  271 GVFQWDNKLWFIKPNTKTKFNSKFLKTEMNFLPHKIYFTALNLNKPLFS---CKLLKNN---------------GYRNIPQESHF------SRVFQRMKRETYPVVDSEIVEPNIIELLIVVTSNFVKRFKKDFRQYILSNVAIATKLLHDPTIKASITXXXXXXXXXXEDYE-------RNNDLHDWSLLSQDRVVSRFCHWVRQKKQLWNYSWDSAILIN-----DGVFSSNAIGIAHLRSMCNDN-NCLAVVDRGFGTGFIIAHELAHQMNARHDFDNAEACSFFEKQYDNKTKYNTIMSTSLFFEYYPFIWSVCSQNVINSFLKSKYSFCLKQRNRHRNLYPHEQINEFFQKYSTGVDYDLNEQCSFAFGEKSEFCETDQNSRKKCSVLYCRLKR--YPICLRADAIIADGTECDVNQHCINGKCLYKNITIAPIDGGWSEYSEWSNCSRPCNGGVQFSYRTCDNPVPADGGRFCTGTKERIRSCNIEECSSFS-DPREESCGKYNLKPY----IPTNDEEFP----------CNLVCITTNHSLKYDIS--LTDGTPCSPFRSDICVKGTCYKTGCDRIVGSKKAIDNCNICAGQNDTCFKKESFFDGSKVAKVRMIRAFRIPPNVYNLFIKKVSQRMTPFTDE--VYDDFELLLVVNRRTVIRRSETIEPLAGGQLRYSGSKNKVETISIKGKLNVGISIVIKVENTKTTLNLPFISYHYFV-----KDIFVWKYLEVITHPCKDQCGGFIEISPACFKKRDNQRYVDHYCSKATKPEPKIIKCGAICGYRWQRATEHYINSTVNKSCPIRCGTGKVKIPFVCQKINNQDDNNSLWETVEENLCFAVDLVDRPIEELNCVGQCNPLLWSYGKWEECPIECGTTFRYRNFICKDNKGLEWQKEWCERHLGLPDNKETCLSFNNCRNL--TRWVTSPWSRCSNSCESELQKRMVYCFRSEKSDEILDEKFLKIHEQISDAFCDIHSPKPITERPCSLNSCYFWIXXXXXXXXXXXXLGFRIQSHECKKKFNKNHEMITVDDKFCLKQNLVKPLDVRMRCFLKKC----------------AIESFWIEMEWSKCSVSCGEGLQYRSLKCGYENENKTLTTWDNNEMCKNKMVPVSIQICKVTPCPKWIYSEWSECEGTCEYGSQHRTVLCTDPISEQILPDSKCDIKNKFPNFQKC-----------------------------------------LLSKLCGHWIVGKWSQCSASCGLGVKTRTITCNYSNGSKSIDHSVCKSVAPFEEIHCQVKPCSTNAFWWLVKPSECYEYNCQPGIMYAHVRCVNRKFQVLYDSKCSRIKHPSYYVGCLNTTCRRYFWTAESWDNIPCPDISCTMKIRNRDVYCVDDYGNIQKDAMCDQSDKPDTWRLCPS 4167
            G F+ ++  +F++P  +   ++     + +  PH IY   L  N    S   C++ +N                G  +I +E+ F      S++  R KR         +  P  +E+++   +  V    ++ + Y+L+ ++I   +  D +I   I I +V +V++  + E           L ++ L  Q + V    H             D+A+LI            + +G+A L ++C+ + +C    + G    F IAHEL H  N  HD       SF  K+   K +Y+ +M+ +L +   P+ WS CSQ  I  FL + +  CL  +   R      Q+         G  YD N QC   FG  S+ C       K C  L+C      +  C      +ADGT C    HC  G C+ +++   P+DG W  +  +S+CSR C GG++ + R CD P P +GGR+C G + + RSCN + C     D RE+ C  ++ K +    +P N    P          C L C     +  Y +   + DGTPC    +DICV+G C + GCD ++ SK   D C +C G N +C      F+ +      ++   +IP    N+ I + S    P  D      D +   ++N   V+  ++    + G    YSGS N +E I+   +L     +V++V       N P + Y + +      ++F W         C   C G      AC +K D+    DH C     P     KC   C  RW     H I  +    C  +CG G   +   C K +         + V     +  D +  P  E  C G C    W Y +W +C   CG   + R   C +  G    +  C     LP      +   NC       W TS WS C  +C   +++R V+C  SE              + + D FC+  S KP + RPC L +C  W     G C+A CG G+++++ +C  +         +DD+ C + +  +P D R  C L  C                   + W    W+ CSVSCG G Q R + C   ++        +   C +   P ++ +C  +PC +W   +WS C  +C +G   R VLC +    Q++ +S CD + +    Q+C                                          LS     W  G W  CS SC  G++ R + C   +G  +   S   S  P E  HC   PC     W      EC +  C  G+    V C     Q+  +  C   K PS     L+       W    W +      SC   ++ R+V C+D +    ++  C    KP T + C S
Sbjct:  153 GTFKANDGEYFLEPVLRADGSAH---DDDHNKPHLIYRQELKRNSFARSHKPCEVSENQMEKTALPSQSSRNTTGDVDIEEEAVFRLEGERSQLHSRNKRF--------LSYPRYVEVMVTADAKMVHHHGQNLQHYVLTLMSIVAAIYKDSSIGNLINIVIVKLVVIHSEQEGPVISFNAATTLRNFCLWQQSQNVPDDAHPSHH---------DTAVLITREDICGAKEKCDTLGLAELGTLCDPSRSCSISEENGLSAAFTIAHELGHVFNVPHDD------SFKCKEAGIKHQYH-VMAPTLNYHTSPWTWSACSQKHITEFLDTGHGECLLDKPNGRTYDLSPQL--------PGSVYDGNRQCELMFGPGSQVCPY----LKHCRRLWCTSAEGVHKGCRTQHMPLADGTSCGPGMHCHRGLCVTRDMETRPVDGEWGPWGPYSSCSRTCGGGIKSTARLCDRPEPRNGGRYCVGRRMKFRSCNTDSCPKGKRDFREKQCSDFDGKHFDINGLPPNVRWLPKYSGIAVKDRCKLYCRVAGTTSFYQLKDRVADGTPCGTETNDICVQGLCRQAGCDHVLNSKAKRDKCGVCGGDNSSCQTLAGVFNSAHYGYNVVV---KIPAGATNIEILQHSYSGRPEDDNYLALSDTQGNFLLNGNFVVSMAKKEINIQGAVFEYSGSNNSIERINSTDRLEA--ELVLQVLCVGNLYN-PDVRYSFNIPIEERSNLFSWDPYGPW-QDCTKMCQGLHRRKIACVRKSDHAVVSDHNCGHLPMPLFVTEKCNMDCELRW-----HIIGKS---DCSSQCGQGYRTLDVHCMKYSVHKG-----QAVPVGDQYCGDQLKPPSRE-PCHGSCVLTRWHYSEWSQCSRSCGGGDKTRESYCVNGFGHRLAESECRE---LPR-----VVLENCNEFPCPSWATSEWSECPVTCGKGMKQRQVWCQLSE--------------DPMRDGFCNA-STKPESLRPCELRACASWHVGPWGSCTATCGHGYQMRAVKCISEIFGT----MLDDRECPQAS--RPSD-RQDCILAPCLAIPEVGATSLPAIPLGRAAQWRHGSWTPCSVSCGRGSQARYVSCRDAHDEVA-----DESNCAHLPRPAAVSLC-FSPCGEWQAGDWSPCSASCGHGKTTRRVLCVN--YHQLVDESYCDPEGRPVTEQECSLAACPPLYSRAPSSSEQPSHVPSRNVPLTHKPGENQDQGAQLSIRGNQWRTGPWGACSRSCAGGLQHRAVVCQDEDGRSAT--SCDGSSKPPESRHCGSGPC---PHWNYGDWGECTQ-TCGGGVKSRFVICQFPNGQMTQEHSCELPKPPSMMQCHLHACPEDVSWYRGPWKSC---SASCGKGVKYREVLCIDQFQRKLEEKYCSHLHKPRTHKACRS 1466

HSP 2 Score: 179.104 bits (453), Expect = 2.107e-44
Identity = 212/814 (26.04%), Postives = 307/814 (37.71%), Query Frame = 1 
Query: 2521 CPIRCGTGKVKIPFVCQKINNQDDNNSLWETVEENLCFAVDLVDRPIEELNCVGQCNPLLWSYGKWEECPIECGTTFRYRNFICKDNKGLEWQKEWCERHLGLPDNKETCLSFNNC-------------------RNL--------------------TRWVTSPWSRCSNSCESELQKRMVYCFRSEKSDEILDEKFLKIHEQISDAFCDIHSPKPITERPCSLNSCYFWIXXXXXXXXXXXXLGFRIQSHECKKKFNKNHEMITVDDKFCLKQNLVKPLDVRMRCFLKKCAIESFWIEMEWSKCSVSCGEGLQYRSLKCGYENENKTLTTWDNNEMCKNKMVPVSIQICKVTPCPKWIYSEWSECEGTCEYGSQHRTVLC----TDPISEQILPDSKCDIKNKFPNFQKCLLSKLCG--HWIVGKWSQCSASCGLGVKTRTITCNYSNGSKSIDHSVCK------SVAPFEEIHCQVK-------PCSTN-AFWWLVKPSECYEYNCQPGIMYAHVRCVNRKFQVLYDSKCSRIKHPSYYVGCLNTTCRRYFWTAESWDNIPCPDISCTMKIRNRDVYCVDDYGNIQKDAMCDQSDKPDTWRLCPSPQNCSNIPRSCKELKSRQSVSKDGEYSLAIDLNWAYFIYCADMNTEEPKEYLTLRELNYARTSKYVSTDVSSCIYEEEMEFNQKCP---------TCKINENLWSITYYNKIRINLSDLSIDVMDDRFSATNGQSFIPFGTAKDCAGSTSCPKGHFKINLRGTGFSVSMETRWNEVYPKYGYRILRKQTSQIVKGWCGGHCSGCSP 4758
            C + CG G       C+  ++        E  +E+ C  +    RP     C   C    W  G W  C   CG     R  +C +   L   + +C+   G P  ++ C S   C                   RN+                     +W T PW  CS SC   LQ R V C      DE          +  S   CD  S KP   R C    C  W     G+C+  CG G + +   C+     N +M    +  C    L KP  + M+C L  C  +  W    W  CS SCG+G++YR + C  + + K        + C +   P + + C+   CP W  ++W EC  TC  G Q R V C    T  +SE +     CD   + P  Q+    + C    W  G W  CS SC      R + C      ++ + S+C       S+      HC+          C+ N  F    K + C +        +  +R       V+Y  +C  I  P  Y   L +      W    W       ++C + I  R V C  + G      +C +  KPD  + C +  N   +  +CKEL+   +V+KDG+Y L +       I+C+ M  E P+EYL L +          S D  S IY   ++   +CP          C+ +      T ++K+R++L  + I   D  FS T     +PF TA DC  +  CP+G F INL GTG  +S   +W          I R Q    V G CGG C  C P
Sbjct: 1160 CSVSCGRGSQARYVSCRDAHD--------EVADESNCAHLP---RPAAVSLCFSPCGE--WQAGDWSPCSASCGHGKTTRRVLCVNYHQLV-DESYCDPE-GRPVTEQEC-SLAACPPLYSRAPSSSEQPSHVPSRNVPLTHKPGENQDQGAQLSIRGNQWRTGPWGACSRSCAGGLQHRAVVC-----QDE----------DGRSATSCD-GSSKPPESRHCGSGPCPHWNYGDWGECTQTCGGGVKSRFVICQ---FPNGQM--TQEHSC---ELPKPPSM-MQCHLHACPEDVSWYRGPWKSCSASCGKGVKYREVLCIDQFQRKL-----EEKYCSHLHKPRTHKACRSGRCPSWKANKWKECSVTCGSGVQQREVYCRLRGTGRVSEDM-----CDPSTR-PQGQRQCWRQDCMRYQWTTGDWLDCSTSCKKKETYRLVKCVNEQNVQA-NESLCDPLTKPLSIKKCRNPHCKYSVVTGDSSQCAGNCGFTSPQKITYCTKIQSSKKHTFHQLR------PVVY-GECPVIPSPQAYKCDLRSCLHVATWKVGKWSKC---SVTCGIGIMERRVACRTENG--WPSDLCLKRLKPDAQKKCYA--NDCKLLTTCKELQVTNNVTKDGDYDLNVR-GRILKIHCSGMQLENPREYLPLVK----------SEDNFSEIYGLRLQNPYECPFNGSRRPDCACENDYLPAGYTVFSKVRVDLESMQIKTADLLFSQTLSGKAVPFATAGDCYSAARCPQGQFSINLAGTGMKISNTAKWLAQGRYASVIIHRSQDGTKVYGRCGGFCGKCIP 1895

HSP 3 Score: 93.2041 bits (230), Expect = 3.173e-18
Identity = 86/357 (24.09%), Postives = 140/357 (39.22%), Query Frame = 1 
Query: 3181 KNHEMITVDDKFCLKQNLVKPLDVRMRCFLKKCAIESFWIEMEWSKCSVSCGEGLQYRSLKCGYENENKTLTTWDNNEMCKNKMVPVSIQICKVT-PCPKWIYSEWSECEGTCEYGSQHRTVLCTDPISEQI-------LPDSKCDIKNKFPNFQKCLLSKLCGHWIVGKWSQCSASCGLGVKTRTITCNYSNGSKSIDHSVCKSVAPFEEIH-CQVKPCSTNAFWWLVKPSECYEYNCQPGIMYAHVRCVNRKFQVLYDSK-CSRIKHPSYYVGCLNTTC-----------------RRYFWTAESWDNIPCPDISCTMKIRNRDVYCVDDYGNIQKDAMCDQSDKPDTWRLCPSP 4170
            +  +   V D  C   +L  PL V  +C +     E  W  +  S CS  CG+G +   + C   + +K       ++ C +++ P S + C  +    +W YSEWS+C  +C  G + R   C +    ++       LP    +  N+FP          C  W   +WS+C  +CG G+K R + C  S     +    C +    E +  C+++ C++    W V P       C  G     V+C++  F  + D + C +   PS    C+   C                 R   W   SW   PC  +SC    + R V C D +  +  ++ C    +P    LC SP
Sbjct:  871 RKSDHAVVSDHNC--GHLPMPLFVTEKCNMD---CELRWHIIGKSDCSSQCGQGYRTLDVHCMKYSVHKGQAVPVGDQYCGDQLKPPSREPCHGSCVLTRWHYSEWSQCSRSCGGGDKTRESYCVNGFGHRLAESECRELPRVVLENCNEFP----------CPSWATSEWSECPVTCGKGMKQRQVWCQLSE--DPMRDGFCNASTKPESLRPCELRACAS----WHVGPWGSCTATCGHGYQMRAVKCISEIFGTMLDDRECPQASRPSDRQDCILAPCLAIPEVGATSLPAIPLGRAAQWRHGSW--TPC-SVSCGRGSQARYVSCRDAHDEVADESNCAHLPRPAAVSLCFSP 1203
[Close]
BLAST of A disintegrin and metalloproteinase with thrombospondin motifs vs. Ensembl Mouse
Match: Adamts20 (a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 20 [Source:MGI Symbol;Acc:MGI:2660628])

HSP 1 Score: 359.377 bits (921), Expect = 1.764e-101
Identity = 344/1376 (25.00%), Postives = 541/1376 (39.32%), Query Frame = 1 
Query:  271 GVFQWDNKLWFIKPNTKTKFNSKFLKTEMNFLPHKIYFTALNLNKPLFS---CKLLKNN---------------GYRNIPQESHF------SRVFQRMKRETYPVVDSEIVEPNIIELLIVVTSNFVKRFKKDFRQYILSNVAIATKLLHDPTIKASITXXXXXXXXXXEDYE-------RNNDLHDWSLLSQDRVVSRFCHWVRQKKQLWNYSWDSAILIN-----DGVFSSNAIGIAHLRSMCNDN-NCLAVVDRGFGTGFIIAHELAHQMNARHDFDNAEACSFFEKQYDNKTKYNTIMSTSLFFEYYPFIWSVCSQNVINSFLKSKYSFCLKQRNRHRNLYPHEQINEFFQKYSTGVDYDLNEQCSFAFGEKSEFCETDQNSRKKCSVLYCRLKR--YPICLRADAIIADGTECDVNQHCINGKCLYKNITIAPIDGGWSEYSEWSNCSRPCNGGVQFSYRTCDNPVPADGGRFCTGTKERIRSCNIEECSSFS-DPREESCGKYNLKPY----IPTNDEEFP----------CNLVCITTNHSLKYDIS--LTDGTPCSPFRSDICVKGTCYKTGCDRIVGSKKAIDNCNICAGQNDTCFKKESFFDGSKVAKVRMIRAFRIPPNVYNLFIKKVSQRMTPFTDE--VYDDFELLLVVNRRTVIRRSETIEPLAGGQLRYSGSKNKVETISIKGKLNVGISIVIKVENTKTTLNLPFISYHYFV-----KDIFVWKYLEVITHPCKDQCGGFIEISPACFKKRDNQRYVDHYCSKATKPEPKIIKCGAICGYRWQRATEHYINSTVNKSCPIRCGTGKVKIPFVCQKINNQDDNNSLWETVEENLCFAVDLVDRPIEELNCVGQCNPLLWSYGKWEECPIECGTTFRYRNFICKDNKGLEWQKEWCERHLGLPDNKETCLSFNNCRNL--TRWVTSPWSRCSNSCESELQKRMVYCFRSEKSDEILDEKFLKIHEQISDAFCDIHSPKPITERPCSLNSCYFWIXXXXXXXXXXXXLGFRIQSHECKKKFNKNHEMITVDDKFCLKQNLVKPLDVRMRCFLKKC----------------AIESFWIEMEWSKCSVSCGEGLQYRSLKCGYENENKTLTTWDNNEMCKNKMVPVSIQICKVTPCPKWIYSEWSECEGTCEYGSQHRTVLCTDPISEQILPDSKCDIKNKFPNFQKC-----------------------------------------LLSKLCGHWIVGKWSQCSASCGLGVKTRTITCNYSNGSKSIDHSVCKSVAPFEEIHCQVKPCSTNAFWWLVKPSECYEYNCQPGIMYAHVRCVNRKFQVLYDSKCSRIKHPSYYVGCLNTTCRRYFWTAESWDNI 4032
            G F+ ++  +F++P  +   ++     + +  PH IY   L  N    S   C++ +N                G  +I +E+ F      S++  R KR         +  P  +E+++   +  V    ++ + Y+L+ ++I   +  D +I   I I +V +V++  + E           L ++ L  Q + V    H             D+A+LI            + +G+A L ++C+ + +C    + G    F IAHEL H  N  HD       SF  K+   K +Y+ +M+ +L +   P+ WS CSQ  I  FL + +  CL  +   R      Q+         G  YD N QC   FG  S+ C       K C  L+C      +  C      +ADGT C    HC  G C+ +++   P+DG W  +  +S+CSR C GG++ + R CD P P +GGR+C G + + RSCN + C     D RE+ C  ++ K +    +P N    P          C L C     +  Y +   + DGTPC    +DICV+G C + GCD ++ SK   D C +C G N +C      F+ +      ++   +IP    N+ I + S    P  D      D +   ++N   V+  ++    + G    YSGS N +E I+   +L     +V++V       N P + Y + +      ++F W         C   C G      AC +K D+    DH C     P     KC   C  RW     H I  +    C  +CG G   +   C K +         + V     +  D +  P  E  C G C    W Y +W +C   CG   + R   C +  G    +  C     LP      +   NC       W TS WS C  +C   +++R V+C  SE              + + D FC+  S KP + RPC L +C  W     G C+A CG G+++++ +C  +         +DD+ C + +  +P D R  C L  C                   + W    W+ CSVSCG G Q R + C   ++        +   C +   P ++ +C  +PC +W   +WS C  +C +G   R VLC +    Q++ +S CD + +    Q+C                                          LS     W  G W  CS SC  G++ R + C   +G  +   S   S  P E  HC   PC     W      EC +  C  G+    V C     Q+  +  C   K PS     L+       W    W ++
Sbjct:  153 GTFKANDGEYFLEPVLRADGSAH---DDDHNKPHLIYRQELKRNSFARSHKPCEVSENQMEKTALPSQSSRNTTGDVDIEEEAVFRLEGERSQLHSRNKRF--------LSYPRYVEVMVTADAKMVHHHGQNLQHYVLTLMSIVAAIYKDSSIGNLINIVIVKLVVIHSEQEGPVISFNAATTLRNFCLWQQSQNVPDDAHPSHH---------DTAVLITREDICGAKEKCDTLGLAELGTLCDPSRSCSISEENGLSAAFTIAHELGHVFNVPHDD------SFKCKEAGIKHQYH-VMAPTLNYHTSPWTWSACSQKHITEFLDTGHGECLLDKPNGRTYDLSPQL--------PGSVYDGNRQCELMFGPGSQVCPY----LKHCRRLWCTSAEGVHKGCRTQHMPLADGTSCGPGMHCHRGLCVTRDMETRPVDGEWGPWGPYSSCSRTCGGGIKSTARLCDRPEPRNGGRYCVGRRMKFRSCNTDSCPKGKRDFREKQCSDFDGKHFDINGLPPNVRWLPKYSGIAVKDRCKLYCRVAGTTSFYQLKDRVADGTPCGTETNDICVQGLCRQAGCDHVLNSKAKRDKCGVCGGDNSSCQTLAGVFNSAHYGYNVVV---KIPAGATNIEILQHSYSGRPEDDNYLALSDTQGNFLLNGNFVVSMAKKEINIQGAVFEYSGSNNSIERINSTDRLEA--ELVLQVLCVGNLYN-PDVRYSFNIPIEERSNLFSWDPYGPWQD-CTKMCQGLHRRKIACVRKSDHAVVSDHNCGHLPMPLFVTEKCNMDCELRW-----HIIGKS---DCSSQCGQGYRTLDVHCMKYSVHKG-----QAVPVGDQYCGDQLKPPSRE-PCHGSCVLTRWHYSEWSQCSRSCGGGDKTRESYCVNGFGHRLAESECRE---LPR-----VVLENCNEFPCPSWATSEWSECPVTCGKGMKQRQVWCQLSE--------------DPMRDGFCNA-STKPESLRPCELRACASWHVGPWGSCTATCGHGYQMRAVKCISEIFG----TMLDDRECPQAS--RPSD-RQDCILAPCLAIPEVGATSLPAIPLGRAAQWRHGSWTPCSVSCGRGSQARYVSCRDAHDEVA-----DESNCAHLPRPAAVSLC-FSPCGEWQAGDWSPCSASCGHGKTTRRVLCVN--YHQLVDESYCDPEGRPVTEQECSLAACPPLYSRAPSSSEQPSHVPSRNVPLTHKPGENQDQGAQLSIRGNQWRTGPWGACSRSCAGGLQHRAVVCQDEDGRSAT--SCDGSSKPPESRHCGSGPC---PHWNYGDWGECTQ-TCGGGVKSRFVICQFPNGQMTQEHSCELPKPPSMMQCHLHACPEDVSWYRGPWKSV 1424

HSP 2 Score: 93.5893 bits (231), Expect = 2.041e-18
Identity = 86/357 (24.09%), Postives = 140/357 (39.22%), Query Frame = 1 
Query: 3181 KNHEMITVDDKFCLKQNLVKPLDVRMRCFLKKCAIESFWIEMEWSKCSVSCGEGLQYRSLKCGYENENKTLTTWDNNEMCKNKMVPVSIQICKVT-PCPKWIYSEWSECEGTCEYGSQHRTVLCTDPISEQI-------LPDSKCDIKNKFPNFQKCLLSKLCGHWIVGKWSQCSASCGLGVKTRTITCNYSNGSKSIDHSVCKSVAPFEEIH-CQVKPCSTNAFWWLVKPSECYEYNCQPGIMYAHVRCVNRKFQVLYDSK-CSRIKHPSYYVGCLNTTC-----------------RRYFWTAESWDNIPCPDISCTMKIRNRDVYCVDDYGNIQKDAMCDQSDKPDTWRLCPSP 4170
            +  +   V D  C   +L  PL V  +C +     E  W  +  S CS  CG+G +   + C   + +K       ++ C +++ P S + C  +    +W YSEWS+C  +C  G + R   C +    ++       LP    +  N+FP          C  W   +WS+C  +CG G+K R + C  S     +    C +    E +  C+++ C++    W V P       C  G     V+C++  F  + D + C +   PS    C+   C                 R   W   SW   PC  +SC    + R V C D +  +  ++ C    +P    LC SP
Sbjct:  871 RKSDHAVVSDHNC--GHLPMPLFVTEKCNMD---CELRWHIIGKSDCSSQCGQGYRTLDVHCMKYSVHKGQAVPVGDQYCGDQLKPPSREPCHGSCVLTRWHYSEWSQCSRSCGGGDKTRESYCVNGFGHRLAESECRELPRVVLENCNEFP----------CPSWATSEWSECPVTCGKGMKQRQVWCQLSE--DPMRDGFCNASTKPESLRPCELRACAS----WHVGPWGSCTATCGHGYQMRAVKCISEIFGTMLDDRECPQASRPSDRQDCILAPCLAIPEVGATSLPAIPLGRAAQWRHGSW--TPC-SVSCGRGSQARYVSCRDAHDEVADESNCAHLPRPAAVSLCFSP 1203
[Close]
BLAST of A disintegrin and metalloproteinase with thrombospondin motifs vs. Ensembl Mouse
Match: Adamts9 (a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 9 [Source:MGI Symbol;Acc:MGI:1916320])

HSP 1 Score: 357.066 bits (915), Expect = 1.353e-99
Identity = 328/1288 (25.47%), Postives = 520/1288 (40.37%), Query Frame = 1 
Query:  535 PNIIELLIVVTSNFVKRFKKDFRQYILSNVAIATKLLHDPTIKASITXXXXXXXXXXEDYERNNDLHDWSLLSQDRVVSRFCHWVRQKKQLWNYSWDSAILIND-----GVFSSNAIGIAHLRSMCND-NNCLAVVDRGFGTGFIIAHELAHQMNARHDFDNAEACSFFEKQYDNKTKYNTIMSTSLFFEYYPFIWSVCSQNVINSFLKSKYSFCLKQRNRHRNLYPHEQINEFFQKYSTGVDYDLNEQCSFAFGEKSEFCETDQNSRKKCSVLYCR--LKRYPICLRADAIIADGTECDVNQHCINGKCLYKNITIAPIDGGWSEYSEWSNCSRPCNGGVQFSYRTCDNPVPADGGRFCTGTKERIRSCNIEEC-SSFSDPREESCGKYNLKPY-----------IPTNDEEF---PCNLVCITTNHSLKYDI--SLTDGTPCSPFRSDICVKGTCYKTGCDRIVGSKKAIDNCNICAGQNDTCFKKESFFDGSKVAKVRMIRAFRIPPNVYNLFIKKVSQRMTPFTDEVYDDFELLL-------VVNRRTVIRRSETIEPLAGGQLRYSGSKNKVETIS----IKGKLNVGISIVIKVEN--TKTTLNLPF--ISYHYFVKDIFVWKYLEVITHPCKDQCGGFIEISPACFKKRDNQRYVDHYCSKATKPEPKIIKCGAICGYRWQRATEHYINSTVNKSCPIRCGTGKVKIPFVCQKINNQDDNNSLWETVEENLCFAVDLVDRPIEELNCVGQCNPLLWSYGKWEECPIECGTTFRYRNFICKDNKGLEWQKEWCERHLGLPDNKETCLSFNNCRNLTRWVTSPWSRCSNSCESELQKRMVYCFRSEKSDEILDEKFLKIHEQISDAFCDIHSPKPITERPCSLNSCYFWIXXXXXXXXXXXXLGFRIQSHECKKKFNKNHEMITVDDKFCLKQNLVKPLDVRMRCFLKKC-----AIE----------SFWIEMEWSKCSVSCGEGLQYRSLKCGYENENKTLTTWDNNEMCKNKMVPVSIQICKVTPCPKWIYSEWSECEGTCEYGSQHRTVLCTDPISEQILPDSKCDIKNKFPNFQKCLLSK----------------------------LCG-HWIVGKWSQCSASCGLGVKTRTITCNYSNGSKSIDHSVCKSVAPFEEIHCQVKPCSTNAFWWLVKPSECYEYNCQPGIMYAHVRCVNRKFQVLYDSKCSRIKHPSYYVGCLNTTC-RRYFWTAESWDNIPCPDISCTMKIRNRDVYCVDDYGNIQKDAMCDQSDKP 4143
            P  +E+++V     V     + + YIL+ ++I   +  D +I   I I +V++V++  + E       +   +    +  FC W   K  L     D+A+L+            + +G+A L ++C+   +C    D G  T F IAHEL H  N  HD  N       + + +       +M+ +L F   P++WS CS+  I  FL + Y  CL      R  YP             G+ Y++N+QC   FG  S+ C        +C  L+C      +  C       ADGTEC+  +HC  G C+ K +    IDG W  +S +  CSR C GG++ + R C+ P P +GG++C G + + +SCN E C     D REE C  ++ K +           +P          C L C    ++  Y +   + DGTPC    +DICV+G C + GCD I+ SK   D C IC G N +C      F+        ++   RIP    ++ +++ S     F+ +  DD  L L       ++N   V+  S+    +    + YSGS N VE ++    I+ +L + +  V K+ N   + + N+P       ++      W+        C   C G       C ++ D     D  C +  +P P    CG  C  RW  A++          C  +CG G   +   C K +  D      E V+++ C +     RP  +  C G+C+   W Y  W EC   C    + R  IC + +        C     +    ++C  F    +   W T  WS C  +C    + R V+C   E              +++SD  CD  + KP   + C    C  W     G+CS  CG G+++++ +C         M  VDD  C      +P D +  C L  C     A+E          + W    W+ CS +CG+G + R + C   +E+ ++    +   C     PV+ + C VTPC +W   +WS C  TC  G   R V+C +  S+ ++  S+CD        Q C +S                             L G  W  G W  CS++C  G + R + C   NG  + D    + + P E+  C+  PC     W      EC +  C  G+    V C         D  C  +  P+    C    C +   W+   W +     +SC    ++R+VYC+   G+  +   C    KP
Sbjct:  292 PRFVEVMVVADHRMVLYHGANLQHYILTLMSIVASIYKDSSIGNLINIVIVNLVVIHNEQE-----GPYINFNAQTTLKNFCQWQHSKNYLGGIQHDTAVLVTREDICRAQDKCDTLGLAELGTICDPYRSCSISEDSGLSTAFTIAHELGHVFNMPHDDSN-------KCKEEGVKSPQHVMAPTLNFYTNPWMWSKCSRKYITEFLDTGYGECLLNEPASRT-YP-------LPSQLPGLLYNVNKQCELIFGPGSQVCPY----MMQCRRLWCNNVDGAHKGCRTQHTPWADGTECEPGKHCKFGFCVPKEMEGPAIDGSWGGWSHFGTCSRTCGGGIKTAIRECNRPEPKNGGKYCVGRRMKFKSCNTEPCMKQKRDFREEQCAHFDGKHFNINGLLPSVRWVPKYSGILMKDRCKLFCRVAGNTAYYQLRDRVIDGTPCGQDTNDICVQGLCRQAGCDHILNSKARKDKCGICGGDNSSCKTVAGTFNTVHYGYNTVV---RIPAGATSIDVRQHS-----FSGKSEDDNYLALSNSKGEFLLNGDFVVSMSKREVRVGSAVIEYSGSDNVVERLNCTDRIEEELLLQVLSVGKLYNPDVRYSFNIPIEDKPQQFYWNSHGPWQ-------ACSKPCQGERRRKLVCTRESDQLTVSDQRCDRLPQPGPVTEACGTDCDLRWHVASK--------SECSAQCGLGYRTLDIHCAKYSRMDGKT---EKVDDSFCSS---QPRPSNQEKCSGECSTGGWRYSAWTECSRSCDGGTQRRRAICVNTRNDVLDDSKCTHQEKV--VVQSCNEF----SCPHWKTGDWSECLVTCGKGHKHRQVWCQFGE--------------DRLSDRMCDPEA-KPEPMQTCQQPECAAWQAGPWGQCSVTCGQGYQLRAVKCI----MGTYMSVVDDNDC--NAATRPTDTQ-DCELASCHPSILALEPRRNAQSIPRTQWRFGSWTPCSATCGKGTRMRYVSC--RDEDGSVA---DESACATLPKPVAKEECSVTPCGQWKALDWSSCSVTCGQGKATRQVVCVN-YSDHVIDRSECDPDYIPETDQDCSMSPCPQWTGLAHPFQNEDFRPRSDSPSRTHVLGGNQWRTGPWGACSSTCAGGSQRRVVVCQDENGYTAND--CVERIKPDEQRACESGPCPQ---WAYGSWGECTKL-CGGGMRTRLVVCQRANGDRFPDLSCEVLDKPTDREQCNTHACPQDAAWSTGPWSSC---SVSCGRGHKHRNVYCLAKDGSHLESDNCKHLPKP 1483

HSP 2 Score: 203.371 bits (516), Expect = 7.525e-52
Identity = 179/707 (25.32%), Postives = 282/707 (39.89%), Query Frame = 1 
Query: 2701 WSYGKWEECPIECGTTFRYRNFICKDNKGLEWQKEWCERHLGLPDNKETCLSFNNCRNLTRWVTSPWSRCSNSCESELQKRMVYCFRSEKSDEILDEKFLKIHEQISDAFCDIHSPKPITERPCSLNSC---YFWIXXXXXXXXXXXXLGFRIQSHECKKKFNKNHEMITVDDKFCLKQNLVKPLDVRMRCFLKKCAIESFWIEMEWSKCSVSCGEGLQYRSLKCGYENENKTLTTWDNNEMCKNKMVPVSIQICKVTPCP--KWIYSEWSECEGTCEYGSQHRTVLCTDPISEQILPDSKCDIKNKFPNFQKCLLSKLCGHWIVGKWSQCSASCGLGVKTRTITCNYSNGSKSIDHSVCKSVAPFEEIHCQVKPCSTNAFWWLVKPSECYEYNCQPGIMYAHVRCVNRKFQVLYDSKCSRIKHPSYYVGCLNTTCRRYFWTAESWDNIPCPDISCTMKIRNRDVYCVDDYGNIQKDAMCDQSDKPDTWRLCPSPQNCSNIPRSCKELKSRQSVSKDGEYSLAIDLNWAYFIYCADMNTEEPKEYLTLRELNYARTSKYVSTDVSSCIYEEEMEFNQKCP---------TCKINENLWSITYYNKIRINLSDLSIDVMDDRFSATNGQSFIPFGTAKDCAGSTSCPKGHFKINLRGTGFSVSMETRWNEVYPKYGYRILRKQTSQIVKGWCGGHCSGCSPLKKFFVE 4779
            W  G W  C   C    + R  +C+D  G  +    C   +  PD +  C S        +W    W  C+  C   ++ R+V C R+               ++  D  C++   KP     C+ ++C     W       CS  CG G + ++  C  K           D   L+ +  K L         +      W    WS+CSVSCG+G+Q R + C                 C +   P S ++C+ +PCP   W   +W +C  TC  GS++R V+C      ++   + CD   + P+ + C L      WI G+WS+CS +CG G + R ++C+                    EI+                  E YEY+ Q       V C   +   +         HP Y   C  +      W   +W +     +SC + + +R V C+ +    Q   +C    KP+  + C +  NC  +P++CKE+K   S S DGEY LA+       ++CA MN++ PKEY+TL   +    S+         +Y   +    +CP          C+ +      + + KIR++L+ + I   D  F+ T+    +PF TA DC  +  CP+G F INL GTG S++   RW          I +      V G CGG+C  C+P     +E
Sbjct: 1328 WRTGPWGACSSTCAGGSQRRVVVCQDENG--YTANDCVERI-KPDEQRACESGP----CPQWAYGSWGECTKLCGGGMRTRLVVCQRANG-------------DRFPDLSCEVLD-KPTDREQCNTHACPQDAAWSTGPWSSCSVSCGRGHKHRNVYCLAK-----------DGSHLESDNCKHLPKPHGHRRCRGGRCPRWKAGAWSQCSVSCGQGVQQRHVGCQIGTHKAA-----RESECSSYSRPESERVCQASPCPLYTWRAEQWQQCTKTCGEGSRYRQVVCVAEDQSEVH-STHCDSDQRPPDRESCSLQPCEYVWITGEWSECSVTCGKGYRQRLVSCS--------------------EIY---------------TGKENYEYSYQ-----TTVNCPGAQPPSV---------HPCYLRDCPVSA----TWRVGNWGSC---SVSCGIGVMHRSVQCLTN--EDQPSHLCPTDTKPEERKACRNVYNC-ELPQNCKEVKKLNSASVDGEYFLAVRGK-PLKVFCAGMNSDYPKEYVTLAHGDSENFSE---------VYGHRLHNPTECPYNGSRRDDCHCRKDYTAAGFSSFQKIRLDLTSMQIITTDLEFARTSEGHPVPFATAGDCYSAAKCPQGRFSINLYGTGLSLTESARWTSQGNYAVSDIKKSPDGTRVVGKCGGYCGKCTPSSGTGLE 1927

HSP 3 Score: 68.5514 bits (166), Expect = 1.001e-10
Identity = 69/241 (28.63%), Postives = 104/241 (43.15%), Query Frame = 1 
Query: 3484 YSEWSECEGTCEYGSQHRTVLCTDPISEQILPDSKCDIKNKFPNFQKCLLSKLCG-----HWIVGKWSQCSASCGLGVKTRTITC-NYS---NGSKSIDHSVCKSVA-PFEEIHCQVKPCSTNAFWWLVKPSECYEYNCQPGIMYAHVRCVNRKFQVLYDSKCSRIKHPSYYVGCLNTTCRRYFWTAESWDNIPCPDISCTMKIRNRDVYCVDDYGNIQ-KDAMCDQSDKPDTWRLCPSPQ 4173
            +  W  C   C+ G + R ++CT    +  + D +CD   + P  Q   +++ CG      W V   S+CSA CGLG +T  I C  YS     ++ +D S C S   P  +  C  + CST   W     +EC   +C  G       CVN +  VL DSKC+  +       C   +C    W    W       ++C    ++R V+C   +G  +  D MCD   KP+  + C  P+
Sbjct:  884 HGPWQACSKPCQ-GERRRKLVCTRESDQLTVSDQRCD---RLP--QPGPVTEACGTDCDLRWHVASKSECSAQCGLGYRTLDIHCAKYSRMDGKTEKVDDSFCSSQPRPSNQEKCSGE-CSTGG-WRYSAWTECSR-SCDGGTQRRRAICVNTRNDVLDDSKCTH-QEKVVVQSCNEFSCP--HWKTGDWSECL---VTCGKGHKHRQVWC--QFGEDRLSDRMCDPEAKPEPMQTCQQPE 1107
[Close]
BLAST of A disintegrin and metalloproteinase with thrombospondin motifs vs. Ensembl Mouse
Match: Adamts6 (a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 6 [Source:MGI Symbol;Acc:MGI:1347348])

HSP 1 Score: 259.996 bits (663), Expect = 2.422e-70
Identity = 251/959 (26.17%), Postives = 387/959 (40.35%), Query Frame = 1 
Query:  271 GVFQWDNKLWFIKPNTKTKFNSKFLKTEMNFLPHKIYFTALNLNKPLFSCK---------------LLKNNGYRNIPQESHFSRVFQRMKRETYPVVDSEIVEPNIIELLIVVTSNFVK-RFKKDFRQYILSNVAIATKLLHDPTIKASITXXXXXXXXXXEDYERNNDLHDWSLLSQDRVVSRFCHWVRQKKQLWNYSWDSAILINDGVFSSNAI------------------GIAHLRSMCN-DNNCLAVVDRGFGTGFIIAHELAHQMNARHD-FDNAEACSFFEKQYDNKTKYNTIMSTSLFFEYYPFIWSVCSQNVINSFLKSKYSFCLKQRNRHRN-LYPHEQINEFFQKYSTGVDYDLNEQCSFAFGEKSEFCETDQNSRKKCSVLYCRLKRYPICLRADAIIADGTECDVNQ----HCINGKCLYKNITIAPIDGGWSEYSEWSNCSRPCNGGVQFSYRTCDNPVPADGGRFCTGTKERIRSCNIEECSSFS-DPREESCG----------KYNLKPYIPTNDEEFPCNLVCITTNHSLKYD--ISLTDGTPCSPFRSDICVKGTCYKTGCDRIVGSKKAIDNCNICAGQNDTCFKKESFFDGSKVAKVRMIRAFRIPPNVYNLFIKKVSQRMTPFT-DEVYDDFELLLVVNRRTVIRRSETIEPLAGGQLRYSGSKNKVETISIKGKL--NVGISIVIKVEN--TKTTLNLPFISYHYFVKDI-FVWKYLEVITHPCKDQCGGFIEISPACFKKRDNQRYV-DHYCSKATKPEPKIIKCGA-ICGYRWQRATEHYINSTVNKSCPIRCGTGKVKIPFVCQKINNQDDNNSLWETVEENLCFAVDLVDRPIEELNCVGQCNPLLWSYGKWEECPIECGTTFRYRNFICKDNK-GLEWQKEWCERHLGLPDNKETCLSFNNCRNLTRWVTSPWSRCSNSCESELQKRMVYCF 2958
            G+   +++ +FI+P   T  +SK    E N  PH IY  +    + ++                  L K + + ++P  +  + +  R +R         +     +E L+V     V    +KD   YILS + I  KL  D ++   + I V  +++L ED       H       D+ +  FC W  QK  L + S  + I  N      NA+                  G+A +  MC  + +C    D G G+ F IAHE+ H     HD   N+      E           +M+  +     PF WS CS++ I SFL S    CL      R+ LYP           + G  YD +EQC F +G  S  C+  +     C  L+C L +   C+      A+GT C         C  G C+        IDGGW  +S W  CSR C GGV  S R CD+P P+ GG++C G ++R RSCN + C   S D RE+ C            YN KPY  T     PC L C+   ++   +   ++ DGT C+    DIC+ G C   GCD I+GS    D C +C G   TC   E FF+ S + +   +   +IP    ++ +++VS            DD+     +N    I      + ++G    Y    ++ E++   G    N+ + ++++ +N   +   N+P +       ++ F+W Y       C   C G ++      K+ D+   V +++C   +KP      C    C   W      +I   +   C   C  G      +C +         +  + EE L +   L  RP+E+ +C  Q  P  W    W EC  +CG+ F++R  +CK +     +    C      P  +  C S   C    RWVT  W +CS  C    Q R V C 
Sbjct:  156 GIIATEDEEYFIEPLKNTTEDSKHFSYE-NGHPHVIYKKSTLQQQHIYDHSHCGVSDLTGSGKPWWLNKTSSFPSLPPIND-THIHHRKRRS--------VSTERFVETLVVADKMMVGYHGRKDIEHYILSVMNIVAKLYRDSSLGNVVNIIVARLIVLTEDQPNLEINH-----HADKSLDSFCKW--QKSILSHQSDGNTIPENGIAHHDNAVLITRYDICTYKNKPCGTLGLASVAGMCEPERSCSINEDIGLGSAFTIAHEIGHNFGMNHDGIGNSCGTKGHEAA--------KLMAAHITANTNPFSWSACSRDYITSFLDSGRGTCLDNEPPKRDFLYP---------AVAPGQVYDADEQCRFQYGATSRQCKYGE----VCRELWC-LSKSNRCVTNSIPAAEGTLCQTGNIEKGWCYQGDCVPFGTWPQSIDGGWGSWSLWGECSRTCGGGVSSSLRHCDSPAPSGGGKYCLGERKRYRSCNTDPCPLGSRDFREKQCADFDSMPFRGKHYNWKPY--TGGGVKPCALNCLAEGYNFYTERAPAVIDGTQCNADSLDICINGECKHVGCDNILGSDAREDRCRVCGGDGSTCDAIEGFFNDS-LPRGGYMEVVQIPRGSVHIEVREVSMSKNYIALKSEGDDY----YINGAWTIDWPRKFD-VSGTAFHYKRPTDEPESLEALGPTSENLIVMVLLQEQNLGIRYKFNVPIVRTGSGDNEVGFMWTYQPWAE--CSATCAGGVQRQEVVCKRLDDNSIVQNNFCDPDSKPPENQRACNTEPCPPEW------FIGDWLE--CSKTCDGGMRTRAVLCIR--------KVGPSEEETLDYGDCLTHRPVEKESCNNQSCPPQWVALDWSECTPKCGSGFKHRIVLCKSSDLSKTFPAAQCPEE-SKPPARIRC-SLGRCPP-PRWVTGDWGQCSAQCGLGQQMRTVQCL 1046

HSP 2 Score: 92.8189 bits (229), Expect = 3.153e-18
Identity = 58/186 (31.18%), Postives = 90/186 (48.39%), Query Frame = 1 
Query: 3202 VDDKFCLKQNLVKPLDVRMRCFLKKCAIESFWIEMEWSKCSVSCGEGLQYRSLKCGYENENKTLTTWDNNEMCKNKMVPVSIQICKVTPCP-KWIYSEWSECEGTCEYGSQHRTVLCTDPISEQILPDSKCDIKNKFPNFQKCLLSKLCG-HWIVGKWSQCSASCGLGVKTRTITCNYSNGSKSID 3753
            V + FC   +  KP + +  C  + C  E  W   +W +CS +C  G++ R++ C  +       T D  +   ++  PV  + C    CP +W+  +WSEC   C  G +HR VLC      +  P ++C  ++K P   +C L +     W+ G W QCSA CGLG + RT+ C    G  S+D
Sbjct:  876 VQNNFCDPDS--KPPENQRACNTEPCPPE--WFIGDWLECSKTCDGGMRTRAVLCIRKVGPSEEETLDYGDCLTHR--PVEKESCNNQSCPPQWVALDWSECTPKCGSGFKHRIVLCKSSDLSKTFPAAQCPEESKPPARIRCSLGRCPPPRWVTGDWGQCSAQCGLGQQMRTVQCLSYTGQASVD 1055

HSP 3 Score: 85.1149 bits (209), Expect = 7.246e-16
Identity = 66/251 (26.29%), Postives = 109/251 (43.43%), Query Frame = 1 
Query: 2884 WVTSPWSRCSNSCESELQKRMVYCFRSEKSDEILDEKFLKIHEQISDAFCDIHSPKPITERPCSLNSC-YFWIXXXXXXXXXXXXLGFRIQSHECKKKFNKNHEMITVDDKFCLKQNLVKPLDVRMRCFLKKCAIESFWIEMEWSKCSVSCGEGLQYRSLKCGYENENKTLTTWDNNEMCKNKMVPVSIQICKVTPC--PKWIYSEWSECEGTCEYGSQHRTVLCTDPISEQILPDSKCDIKNKFPNFQKC 3627
            W   PW+ CS +C   +Q++ V C R       LD+  +     + + FCD  S  P  +R C+   C   W      +CS  C  G R ++  C +K   + E  T+D   CL    V+    +  C  + C  +  W+ ++WS+C+  CG G ++R + C   + +KT         C  +  P +   C +  C  P+W+  +W +C   C  G Q RTV C     +  +    C    + P+ Q+C
Sbjct:  844 WTYQPWAECSATCAGGVQRQEVVCKR-------LDDNSI-----VQNNFCDPDSKPPENQRACNTEPCPPEWFIGDWLECSKTCDGGMRTRAVLCIRKVGPSEEE-TLDYGDCLTHRPVE----KESCNNQSCPPQ--WVALDWSECTPKCGSGFKHRIVLCKSSDLSKTFPA----AQCPEESKPPARIRCSLGRCPPPRWVTGDWGQCSAQCGLGQQMRTVQCLSYTGQASV---DCPETVRPPSMQQC 1068

HSP 4 Score: 80.4925 bits (197), Expect = 1.951e-14
Identity = 63/248 (25.40%), Postives = 102/248 (41.13%), Query Frame = 1 
Query: 3478 WIYSEWSECEGTCEYGSQHRTVLCTDPISEQILPDSKCDIKNKFPNFQKCLLSKLC-GHWIVGKWSQCSASCGLGVKTRTITCNYSNG---SKSIDHSVCKSVAPFEEIHCQVKPCSTNAFWWLVKPSECYEYNCQPGIMYAHVRCVNRKFQVLYD-SKCSRIKHPSYYVGCLNTTCRRYFWTAESWDNIPCPDISCTMKIRNRDVYCVDDYGNIQKDAMCDQSDKPDTWRLCPSPQNCSNIPRSCKE 4206
            W Y  W+EC  TC  G Q + V+C       I+ ++ CD  +K P  Q+   ++ C   W +G W +CS +C  G++TR + C    G    +++D+  C +  P E+  C  + C     W  +  SEC    C  G  +  V C +      +  ++C     P   + C    C    W    W         C +  + R V C+   G    D  C ++ +P + + C S   C + P S  E
Sbjct:  844 WTYQPWAECSATCAGGVQRQEVVCKRLDDNSIVQNNFCDPDSKPPENQRACNTEPCPPEWFIGDWLECSKTCDGGMRTRAVLCIRKVGPSEEETLDYGDCLTHRPVEKESCNNQSCPPQ--WVALDWSECTP-KCGSGFKHRIVLCKSSDLSKTFPAAQCPEESKPPARIRCSLGRCPPPRWVTGDWGQC---SAQCGLGQQMRTVQCLSYTGQASVD--CPETVRPPSMQQCDS--KCDSTPLSSTE 1081
[Close]
BLAST of A disintegrin and metalloproteinase with thrombospondin motifs vs. Ensembl Mouse
Match: Adamts6 (a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 6 [Source:MGI Symbol;Acc:MGI:1347348])

HSP 1 Score: 259.996 bits (663), Expect = 2.422e-70
Identity = 251/959 (26.17%), Postives = 387/959 (40.35%), Query Frame = 1 
Query:  271 GVFQWDNKLWFIKPNTKTKFNSKFLKTEMNFLPHKIYFTALNLNKPLFSCK---------------LLKNNGYRNIPQESHFSRVFQRMKRETYPVVDSEIVEPNIIELLIVVTSNFVK-RFKKDFRQYILSNVAIATKLLHDPTIKASITXXXXXXXXXXEDYERNNDLHDWSLLSQDRVVSRFCHWVRQKKQLWNYSWDSAILINDGVFSSNAI------------------GIAHLRSMCN-DNNCLAVVDRGFGTGFIIAHELAHQMNARHD-FDNAEACSFFEKQYDNKTKYNTIMSTSLFFEYYPFIWSVCSQNVINSFLKSKYSFCLKQRNRHRN-LYPHEQINEFFQKYSTGVDYDLNEQCSFAFGEKSEFCETDQNSRKKCSVLYCRLKRYPICLRADAIIADGTECDVNQ----HCINGKCLYKNITIAPIDGGWSEYSEWSNCSRPCNGGVQFSYRTCDNPVPADGGRFCTGTKERIRSCNIEECSSFS-DPREESCG----------KYNLKPYIPTNDEEFPCNLVCITTNHSLKYD--ISLTDGTPCSPFRSDICVKGTCYKTGCDRIVGSKKAIDNCNICAGQNDTCFKKESFFDGSKVAKVRMIRAFRIPPNVYNLFIKKVSQRMTPFT-DEVYDDFELLLVVNRRTVIRRSETIEPLAGGQLRYSGSKNKVETISIKGKL--NVGISIVIKVEN--TKTTLNLPFISYHYFVKDI-FVWKYLEVITHPCKDQCGGFIEISPACFKKRDNQRYV-DHYCSKATKPEPKIIKCGA-ICGYRWQRATEHYINSTVNKSCPIRCGTGKVKIPFVCQKINNQDDNNSLWETVEENLCFAVDLVDRPIEELNCVGQCNPLLWSYGKWEECPIECGTTFRYRNFICKDNK-GLEWQKEWCERHLGLPDNKETCLSFNNCRNLTRWVTSPWSRCSNSCESELQKRMVYCF 2958
            G+   +++ +FI+P   T  +SK    E N  PH IY  +    + ++                  L K + + ++P  +  + +  R +R         +     +E L+V     V    +KD   YILS + I  KL  D ++   + I V  +++L ED       H       D+ +  FC W  QK  L + S  + I  N      NA+                  G+A +  MC  + +C    D G G+ F IAHE+ H     HD   N+      E           +M+  +     PF WS CS++ I SFL S    CL      R+ LYP           + G  YD +EQC F +G  S  C+  +     C  L+C L +   C+      A+GT C         C  G C+        IDGGW  +S W  CSR C GGV  S R CD+P P+ GG++C G ++R RSCN + C   S D RE+ C            YN KPY  T     PC L C+   ++   +   ++ DGT C+    DIC+ G C   GCD I+GS    D C +C G   TC   E FF+ S + +   +   +IP    ++ +++VS            DD+     +N    I      + ++G    Y    ++ E++   G    N+ + ++++ +N   +   N+P +       ++ F+W Y       C   C G ++      K+ D+   V +++C   +KP      C    C   W      +I   +   C   C  G      +C +         +  + EE L +   L  RP+E+ +C  Q  P  W    W EC  +CG+ F++R  +CK +     +    C      P  +  C S   C    RWVT  W +CS  C    Q R V C 
Sbjct:  156 GIIATEDEEYFIEPLKNTTEDSKHFSYE-NGHPHVIYKKSTLQQQHIYDHSHCGVSDLTGSGKPWWLNKTSSFPSLPPIND-THIHHRKRRS--------VSTERFVETLVVADKMMVGYHGRKDIEHYILSVMNIVAKLYRDSSLGNVVNIIVARLIVLTEDQPNLEINH-----HADKSLDSFCKW--QKSILSHQSDGNTIPENGIAHHDNAVLITRYDICTYKNKPCGTLGLASVAGMCEPERSCSINEDIGLGSAFTIAHEIGHNFGMNHDGIGNSCGTKGHEAA--------KLMAAHITANTNPFSWSACSRDYITSFLDSGRGTCLDNEPPKRDFLYP---------AVAPGQVYDADEQCRFQYGATSRQCKYGE----VCRELWC-LSKSNRCVTNSIPAAEGTLCQTGNIEKGWCYQGDCVPFGTWPQSIDGGWGSWSLWGECSRTCGGGVSSSLRHCDSPAPSGGGKYCLGERKRYRSCNTDPCPLGSRDFREKQCADFDSMPFRGKHYNWKPY--TGGGVKPCALNCLAEGYNFYTERAPAVIDGTQCNADSLDICINGECKHVGCDNILGSDAREDRCRVCGGDGSTCDAIEGFFNDS-LPRGGYMEVVQIPRGSVHIEVREVSMSKNYIALKSEGDDY----YINGAWTIDWPRKFD-VSGTAFHYKRPTDEPESLEALGPTSENLIVMVLLQEQNLGIRYKFNVPIVRTGSGDNEVGFMWTYQPWAE--CSATCAGGVQRQEVVCKRLDDNSIVQNNFCDPDSKPPENQRACNTEPCPPEW------FIGDWLE--CSKTCDGGMRTRAVLCIR--------KVGPSEEETLDYGDCLTHRPVEKESCNNQSCPPQWVALDWSECTPKCGSGFKHRIVLCKSSDLSKTFPAAQCPEE-SKPPARIRC-SLGRCPP-PRWVTGDWGQCSAQCGLGQQMRTVQCL 1046

HSP 2 Score: 92.8189 bits (229), Expect = 3.153e-18
Identity = 58/186 (31.18%), Postives = 90/186 (48.39%), Query Frame = 1 
Query: 3202 VDDKFCLKQNLVKPLDVRMRCFLKKCAIESFWIEMEWSKCSVSCGEGLQYRSLKCGYENENKTLTTWDNNEMCKNKMVPVSIQICKVTPCP-KWIYSEWSECEGTCEYGSQHRTVLCTDPISEQILPDSKCDIKNKFPNFQKCLLSKLCG-HWIVGKWSQCSASCGLGVKTRTITCNYSNGSKSID 3753
            V + FC   +  KP + +  C  + C  E  W   +W +CS +C  G++ R++ C  +       T D  +   ++  PV  + C    CP +W+  +WSEC   C  G +HR VLC      +  P ++C  ++K P   +C L +     W+ G W QCSA CGLG + RT+ C    G  S+D
Sbjct:  876 VQNNFCDPDS--KPPENQRACNTEPCPPE--WFIGDWLECSKTCDGGMRTRAVLCIRKVGPSEEETLDYGDCLTHR--PVEKESCNNQSCPPQWVALDWSECTPKCGSGFKHRIVLCKSSDLSKTFPAAQCPEESKPPARIRCSLGRCPPPRWVTGDWGQCSAQCGLGQQMRTVQCLSYTGQASVD 1055

HSP 3 Score: 85.1149 bits (209), Expect = 7.246e-16
Identity = 66/251 (26.29%), Postives = 109/251 (43.43%), Query Frame = 1 
Query: 2884 WVTSPWSRCSNSCESELQKRMVYCFRSEKSDEILDEKFLKIHEQISDAFCDIHSPKPITERPCSLNSC-YFWIXXXXXXXXXXXXLGFRIQSHECKKKFNKNHEMITVDDKFCLKQNLVKPLDVRMRCFLKKCAIESFWIEMEWSKCSVSCGEGLQYRSLKCGYENENKTLTTWDNNEMCKNKMVPVSIQICKVTPC--PKWIYSEWSECEGTCEYGSQHRTVLCTDPISEQILPDSKCDIKNKFPNFQKC 3627
            W   PW+ CS +C   +Q++ V C R       LD+  +     + + FCD  S  P  +R C+   C   W      +CS  C  G R ++  C +K   + E  T+D   CL    V+    +  C  + C  +  W+ ++WS+C+  CG G ++R + C   + +KT         C  +  P +   C +  C  P+W+  +W +C   C  G Q RTV C     +  +    C    + P+ Q+C
Sbjct:  844 WTYQPWAECSATCAGGVQRQEVVCKR-------LDDNSI-----VQNNFCDPDSKPPENQRACNTEPCPPEWFIGDWLECSKTCDGGMRTRAVLCIRKVGPSEEE-TLDYGDCLTHRPVE----KESCNNQSCPPQ--WVALDWSECTPKCGSGFKHRIVLCKSSDLSKTFPA----AQCPEESKPPARIRCSLGRCPPPRWVTGDWGQCSAQCGLGQQMRTVQCLSYTGQASV---DCPETVRPPSMQQC 1068

HSP 4 Score: 80.4925 bits (197), Expect = 1.951e-14
Identity = 63/248 (25.40%), Postives = 102/248 (41.13%), Query Frame = 1 
Query: 3478 WIYSEWSECEGTCEYGSQHRTVLCTDPISEQILPDSKCDIKNKFPNFQKCLLSKLC-GHWIVGKWSQCSASCGLGVKTRTITCNYSNG---SKSIDHSVCKSVAPFEEIHCQVKPCSTNAFWWLVKPSECYEYNCQPGIMYAHVRCVNRKFQVLYD-SKCSRIKHPSYYVGCLNTTCRRYFWTAESWDNIPCPDISCTMKIRNRDVYCVDDYGNIQKDAMCDQSDKPDTWRLCPSPQNCSNIPRSCKE 4206
            W Y  W+EC  TC  G Q + V+C       I+ ++ CD  +K P  Q+   ++ C   W +G W +CS +C  G++TR + C    G    +++D+  C +  P E+  C  + C     W  +  SEC    C  G  +  V C +      +  ++C     P   + C    C    W    W         C +  + R V C+   G    D  C ++ +P + + C S   C + P S  E
Sbjct:  844 WTYQPWAECSATCAGGVQRQEVVCKRLDDNSIVQNNFCDPDSKPPENQRACNTEPCPPEWFIGDWLECSKTCDGGMRTRAVLCIRKVGPSEEETLDYGDCLTHRPVEKESCNNQSCPPQ--WVALDWSECTP-KCGSGFKHRIVLCKSSDLSKTFPAAQCPEESKPPARIRCSLGRCPPPRWVTGDWGQC---SAQCGLGQQMRTVQCLSYTGQASVD--CPETVRPPSMQQCDS--KCDSTPLSSTE 1081
[Close]
BLAST of A disintegrin and metalloproteinase with thrombospondin motifs vs. UniProt/SwissProt
Match: sp|P59511|ATS20_MOUSE (A disintegrin and metalloproteinase with thrombospondin motifs 20 OS=Mus musculus OX=10090 GN=Adamts20 PE=2 SV=2)

HSP 1 Score: 374.785 bits (961), Expect = 2.294e-104
Identity = 356/1421 (25.05%), Postives = 560/1421 (39.41%), Query Frame = 1 
Query:  271 GVFQWDNKLWFIKPNTKTKFNSKFLKTEMNFLPHKIYFTALNLNKPLFS---CKLLKNN---------------GYRNIPQESHF------SRVFQRMKRETYPVVDSEIVEPNIIELLIVVTSNFVKRFKKDFRQYILSNVAIATKLLHDPTIKASITXXXXXXXXXXEDYE-------RNNDLHDWSLLSQDRVVSRFCHWVRQKKQLWNYSWDSAILIN-----DGVFSSNAIGIAHLRSMCNDN-NCLAVVDRGFGTGFIIAHELAHQMNARHDFDNAEACSFFEKQYDNKTKYNTIMSTSLFFEYYPFIWSVCSQNVINSFLKSKYSFCLKQRNRHRNLYPHEQINEFFQKYSTGVDYDLNEQCSFAFGEKSEFCETDQNSRKKCSVLYCRLKR--YPICLRADAIIADGTECDVNQHCINGKCLYKNITIAPIDGGWSEYSEWSNCSRPCNGGVQFSYRTCDNPVPADGGRFCTGTKERIRSCNIEECSSFS-DPREESCGKYNLKPY----IPTNDEEFP----------CNLVCITTNHSLKYDIS--LTDGTPCSPFRSDICVKGTCYKTGCDRIVGSKKAIDNCNICAGQNDTCFKKESFFDGSKVAKVRMIRAFRIPPNVYNLFIKKVSQRMTPFTDE--VYDDFELLLVVNRRTVIRRSETIEPLAGGQLRYSGSKNKVETISIKGKLNVGISIVIKVENTKTTLNLPFISYHYFV-----KDIFVWKYLEVITHPCKDQCGGFIEISPACFKKRDNQRYVDHYCSKATKPEPKIIKCGAICGYRWQRATEHYINSTVNKSCPIRCGTGKVKIPFVCQKINNQDDNNSLWETVEENLCFAVDLVDRPIEELNCVGQCNPLLWSYGKWEECPIECGTTFRYRNFICKDNKGLEWQKEWCERHLGLPDNKETCLSFNNCRNL--TRWVTSPWSRCSNSCESELQKRMVYCFRSEKSDEILDEKFLKIHEQISDAFCDIHSPKPITERPCSLNSCYFWIXXXXXXXXXXXXLGFRIQSHECKKKFNKNHEMITVDDKFCLKQNLVKPLDVRMRCFLKKC----------------AIESFWIEMEWSKCSVSCGEGLQYRSLKCGYENENKTLTTWDNNEMCKNKMVPVSIQICKVTPCPKWIYSEWSECEGTCEYGSQHRTVLCTDPISEQILPDSKCDIKNKFPNFQKC-----------------------------------------LLSKLCGHWIVGKWSQCSASCGLGVKTRTITCNYSNGSKSIDHSVCKSVAPFEEIHCQVKPCSTNAFWWLVKPSECYEYNCQPGIMYAHVRCVNRKFQVLYDSKCSRIKHPSYYVGCLNTTCRRYFWTAESWDNIPCPDISCTMKIRNRDVYCVDDYGNIQKDAMCDQSDKPDTWRLCPS 4167
            G F+ ++  +F++P  +   ++     + +  PH IY   L  N    S   C++ +N                G  +I +E+ F      S++  R KR         +  P  +E+++   +  V    ++ + Y+L+ ++I   +  D +I   I I +V +V++  + E           L ++ L  Q + V    H             D+A+LI            + +G+A L ++C+ + +C    + G    F IAHEL H  N  HD       SF  K+   K +Y+ +M+ +L +   P+ WS CSQ  I  FL + +  CL  +   R      Q+         G  YD N QC   FG  S+ C       K C  L+C      +  C      +ADGT C    HC  G C+ +++   P+DG W  +  +S+CSR C GG++ + R CD P P +GGR+C G + + RSCN + C     D RE+ C  ++ K +    +P N    P          C L C     +  Y +   + DGTPC    +DICV+G C + GCD ++ SK   D C +C G N +C      F+ +      ++   +IP    N+ I + S    P  D      D +   ++N   V+  ++    + G    YSGS N +E I+   +L     +V++V       N P + Y + +      ++F W         C   C G      AC +K D+    DH C     P     KC   C  RW     H I  +    C  +CG G   +   C K +         + V     +  D +  P  E  C G C    W Y +W +C   CG   + R   C +  G    +  C     LP      +   NC       W TS WS C  +C   +++R V+C  SE              + + D FC+  S KP + RPC L +C  W     G C+A CG G+++++ +C  +         +DD+ C + +  +P D R  C L  C                   + W    W+ CSVSCG G Q R + C   ++        +   C +   P ++ +C  +PC +W   +WS C  +C +G   R VLC +    Q++ +S CD + +    Q+C                                          LS     W  G W  CS SC  G++ R + C   +G  +   S   S  P E  HC   PC     W      EC +  C  G+    V C     Q+  +  C   K PS     L+       W    W +      SC   ++ R+V C+D +    ++  C    KP T + C S
Sbjct:  153 GTFKANDGEYFLEPVLRADGSAH---DDDHNKPHLIYRQELKRNSFARSHKPCEVSENQMEKTALPSQSSRNTTGDVDIEEEAVFRLEGERSQLHSRNKRF--------LSYPRYVEVMVTADAKMVHHHGQNLQHYVLTLMSIVAAIYKDSSIGNLINIVIVKLVVIHSEQEGPVISFNAATTLRNFCLWQQSQNVPDDAHPSHH---------DTAVLITREDICGAKEKCDTLGLAELGTLCDPSRSCSISEENGLSAAFTIAHELGHVFNVPHDD------SFKCKEAGIKHQYH-VMAPTLNYHTSPWTWSACSQKHITEFLDTGHGECLLDKPNGRTYDLSPQL--------PGSVYDGNRQCELMFGPGSQVCPY----LKHCRRLWCTSAEGVHKGCRTQHMPLADGTSCGPGMHCHRGLCVTRDMETRPVDGEWGPWGPYSSCSRTCGGGIKSTARLCDRPEPRNGGRYCVGRRMKFRSCNTDSCPKGKRDFREKQCSDFDGKHFDINGLPPNVRWLPKYSGIAVKDRCKLYCRVAGTTSFYQLKDRVADGTPCGTETNDICVQGLCRQAGCDHVLNSKAKRDKCGVCGGDNSSCQTLAGVFNSAHYGYNVVV---KIPAGATNIEILQHSYSGRPEDDNYLALSDTQGNFLLNGNFVVSMAKKEINIQGAVFEYSGSNNSIERINSTDRLEA--ELVLQVLCVGNLYN-PDVRYSFNIPIEERSNLFSWDPYGPW-QDCTKMCQGLHRRKIACVRKSDHAVVSDHNCGHLPMPLFVTEKCNMDCELRW-----HIIGKS---DCSSQCGQGYRTLDVHCMKYSVHKG-----QAVPVGDQYCGDQLKPPSRE-PCHGSCVLTRWHYSEWSQCSRSCGGGDKTRESYCVNGFGHRLAESECRE---LPR-----VVLENCNEFPCPSWATSEWSECPVTCGKGMKQRQVWCQLSE--------------DPMRDGFCNA-STKPESLRPCELRACASWHVGPWGSCTATCGHGYQMRAVKCISEIFGT----MLDDRECPQAS--RPSD-RQDCILAPCLAIPEVGATSLPAIPLGRAAQWRHGSWTPCSVSCGRGSQARYVSCRDAHDEVA-----DESNCAHLPRPAAVSLC-FSPCGEWQAGDWSPCSASCGHGKTTRRVLCVN--YHQLVDESYCDPEGRPVTEQECSLAACPPLYSRAPSSSEQPSHVPSRNVPLTHKPGENQDQGAQLSIRGNQWRTGPWGACSRSCAGGLQHRAVVCQDEDGRSAT--SCDGSSKPPESRHCGSGPC---PHWNYGDWGECTQ-TCGGGVKSRFVICQFPNGQMTQEHSCELPKPPSMMQCHLHACPEDVSWYRGPWKSC---SASCGKGVKYREVLCIDQFQRKLEEKYCSHLHKPRTHKACRS 1466

HSP 2 Score: 179.104 bits (453), Expect = 1.474e-43
Identity = 212/814 (26.04%), Postives = 307/814 (37.71%), Query Frame = 1 
Query: 2521 CPIRCGTGKVKIPFVCQKINNQDDNNSLWETVEENLCFAVDLVDRPIEELNCVGQCNPLLWSYGKWEECPIECGTTFRYRNFICKDNKGLEWQKEWCERHLGLPDNKETCLSFNNC-------------------RNL--------------------TRWVTSPWSRCSNSCESELQKRMVYCFRSEKSDEILDEKFLKIHEQISDAFCDIHSPKPITERPCSLNSCYFWIXXXXXXXXXXXXLGFRIQSHECKKKFNKNHEMITVDDKFCLKQNLVKPLDVRMRCFLKKCAIESFWIEMEWSKCSVSCGEGLQYRSLKCGYENENKTLTTWDNNEMCKNKMVPVSIQICKVTPCPKWIYSEWSECEGTCEYGSQHRTVLC----TDPISEQILPDSKCDIKNKFPNFQKCLLSKLCG--HWIVGKWSQCSASCGLGVKTRTITCNYSNGSKSIDHSVCK------SVAPFEEIHCQVK-------PCSTN-AFWWLVKPSECYEYNCQPGIMYAHVRCVNRKFQVLYDSKCSRIKHPSYYVGCLNTTCRRYFWTAESWDNIPCPDISCTMKIRNRDVYCVDDYGNIQKDAMCDQSDKPDTWRLCPSPQNCSNIPRSCKELKSRQSVSKDGEYSLAIDLNWAYFIYCADMNTEEPKEYLTLRELNYARTSKYVSTDVSSCIYEEEMEFNQKCP---------TCKINENLWSITYYNKIRINLSDLSIDVMDDRFSATNGQSFIPFGTAKDCAGSTSCPKGHFKINLRGTGFSVSMETRWNEVYPKYGYRILRKQTSQIVKGWCGGHCSGCSP 4758
            C + CG G       C+  ++        E  +E+ C  +    RP     C   C    W  G W  C   CG     R  +C +   L   + +C+   G P  ++ C S   C                   RN+                     +W T PW  CS SC   LQ R V C      DE          +  S   CD  S KP   R C    C  W     G+C+  CG G + +   C+     N +M    +  C    L KP  + M+C L  C  +  W    W  CS SCG+G++YR + C  + + K        + C +   P + + C+   CP W  ++W EC  TC  G Q R V C    T  +SE +     CD   + P  Q+    + C    W  G W  CS SC      R + C      ++ + S+C       S+      HC+          C+ N  F    K + C +        +  +R       V+Y  +C  I  P  Y   L +      W    W       ++C + I  R V C  + G      +C +  KPD  + C +  N   +  +CKEL+   +V+KDG+Y L +       I+C+ M  E P+EYL L +          S D  S IY   ++   +CP          C+ +      T ++K+R++L  + I   D  FS T     +PF TA DC  +  CP+G F INL GTG  +S   +W          I R Q    V G CGG C  C P
Sbjct: 1160 CSVSCGRGSQARYVSCRDAHD--------EVADESNCAHLP---RPAAVSLCFSPCGE--WQAGDWSPCSASCGHGKTTRRVLCVNYHQLV-DESYCDPE-GRPVTEQEC-SLAACPPLYSRAPSSSEQPSHVPSRNVPLTHKPGENQDQGAQLSIRGNQWRTGPWGACSRSCAGGLQHRAVVC-----QDE----------DGRSATSCD-GSSKPPESRHCGSGPCPHWNYGDWGECTQTCGGGVKSRFVICQ---FPNGQM--TQEHSC---ELPKPPSM-MQCHLHACPEDVSWYRGPWKSCSASCGKGVKYREVLCIDQFQRKL-----EEKYCSHLHKPRTHKACRSGRCPSWKANKWKECSVTCGSGVQQREVYCRLRGTGRVSEDM-----CDPSTR-PQGQRQCWRQDCMRYQWTTGDWLDCSTSCKKKETYRLVKCVNEQNVQA-NESLCDPLTKPLSIKKCRNPHCKYSVVTGDSSQCAGNCGFTSPQKITYCTKIQSSKKHTFHQLR------PVVY-GECPVIPSPQAYKCDLRSCLHVATWKVGKWSKC---SVTCGIGIMERRVACRTENG--WPSDLCLKRLKPDAQKKCYA--NDCKLLTTCKELQVTNNVTKDGDYDLNVR-GRILKIHCSGMQLENPREYLPLVK----------SEDNFSEIYGLRLQNPYECPFNGSRRPDCACENDYLPAGYTVFSKVRVDLESMQIKTADLLFSQTLSGKAVPFATAGDCYSAARCPQGQFSINLAGTGMKISNTAKWLAQGRYASVIIHRSQDGTKVYGRCGGFCGKCIP 1895

HSP 3 Score: 93.2041 bits (230), Expect = 2.219e-17
Identity = 86/357 (24.09%), Postives = 140/357 (39.22%), Query Frame = 1 
Query: 3181 KNHEMITVDDKFCLKQNLVKPLDVRMRCFLKKCAIESFWIEMEWSKCSVSCGEGLQYRSLKCGYENENKTLTTWDNNEMCKNKMVPVSIQICKVT-PCPKWIYSEWSECEGTCEYGSQHRTVLCTDPISEQI-------LPDSKCDIKNKFPNFQKCLLSKLCGHWIVGKWSQCSASCGLGVKTRTITCNYSNGSKSIDHSVCKSVAPFEEIH-CQVKPCSTNAFWWLVKPSECYEYNCQPGIMYAHVRCVNRKFQVLYDSK-CSRIKHPSYYVGCLNTTC-----------------RRYFWTAESWDNIPCPDISCTMKIRNRDVYCVDDYGNIQKDAMCDQSDKPDTWRLCPSP 4170
            +  +   V D  C   +L  PL V  +C +     E  W  +  S CS  CG+G +   + C   + +K       ++ C +++ P S + C  +    +W YSEWS+C  +C  G + R   C +    ++       LP    +  N+FP          C  W   +WS+C  +CG G+K R + C  S     +    C +    E +  C+++ C++    W V P       C  G     V+C++  F  + D + C +   PS    C+   C                 R   W   SW   PC  +SC    + R V C D +  +  ++ C    +P    LC SP
Sbjct:  871 RKSDHAVVSDHNC--GHLPMPLFVTEKCNMD---CELRWHIIGKSDCSSQCGQGYRTLDVHCMKYSVHKGQAVPVGDQYCGDQLKPPSREPCHGSCVLTRWHYSEWSQCSRSCGGGDKTRESYCVNGFGHRLAESECRELPRVVLENCNEFP----------CPSWATSEWSECPVTCGKGMKQRQVWCQLSE--DPMRDGFCNASTKPESLRPCELRACAS----WHVGPWGSCTATCGHGYQMRAVKCISEIFGTMLDDRECPQASRPSDRQDCILAPCLAIPEVGATSLPAIPLGRAAQWRHGSW--TPC-SVSCGRGSQARYVSCRDAHDEVADESNCAHLPRPAAVSLCFSP 1203
[Close]
BLAST of A disintegrin and metalloproteinase with thrombospondin motifs vs. UniProt/SwissProt
Match: sp|P59510|ATS20_HUMAN (A disintegrin and metalloproteinase with thrombospondin motifs 20 OS=Homo sapiens OX=9606 GN=ADAMTS20 PE=2 SV=2)

HSP 1 Score: 367.466 bits (942), Expect = 4.222e-102
Identity = 379/1416 (26.77%), Postives = 576/1416 (40.68%), Query Frame = 1 
Query:  271 GVFQWDNKLWFIKPNTKTKFNSKFLKTEMNFLPHKIYFTALN--LNKPLFSCKL---------LKNNGYRNIPQESHF--SRVFQRMKRETYPVVDSE--------IVEPNIIELLIVVTSNFVKRFKKDFRQYILSNVAIATKLLHDPTIKASITXXXXXXXXXXEDYERNNDLHDWSLLSQDRVVSRFCHWVRQKKQLWNYS---WDSAILIN-DGVFSS----NAIGIAHLRSMCND-NNCLAVVDRGFGTGFIIAHELAHQMNARHDFDNAEACSFFEKQYDNKTKYNTIMSTSLFFEYYPFIWSVCSQNVINSFLKSKYSFCLKQRNRHRNLYPHEQINEFFQKYSTGVDYDLNEQCSFAFGEKSEFCETDQNSRKKCSVLYCRL--KRYPICLRADAIIADGTECDVNQHCINGKCLYKNITIAPIDGGWSEYSEWSNCSRPCNGGVQFSYRTCDNPVPADGGRFCTGTKERIRSCNIEECSSFS-DPREESCGKYNLKPY----IPTNDEEFP----------CNLVC--ITTNHSLKYDISLTDGTPCSPFRSDICVKGTCYKTGCDRIVGSKKAIDNCNICAGQNDTCFKKESFFDGSKVAKVRMIRAFRIPPNVYNLFIKKVSQRMTPFTDEVY---DDFELLLVVNRRTVIRRSETIEPLAGGQ--LRYSGSKNKVETISIKGKLNVGISI-VIKVENTKTTLNLPFISYHYFV-----KDIFVWKYLEVITHPCKDQCGGFIEISPACFKKRDNQRYVDHYCSKATKPEPKIIKCGAICGYRWQRATEHYINSTVNKSCPIRCGTGKVKIPFVCQKINNQDDNNSLWETVEENLCFAVDLVDRPIEELNCVGQCNPLLWSYGKWEECPIECGTTFRYRNFICKDNKGLEWQKEWCERHLGLPDNKETCLSFNNCRNLTRWVTSPWSRCSNSCESELQKRMVYCFRSEKSDEILDEKFLKIHEQISDAFCDIHSPKPITERPCSLNSCYFWIXXXXXXXXXXXXLGFRIQSHECKKKFNKNHEMITVDDKFCLKQNLVKPLDVRMRCFLKKCAIES----------------FWIEMEWSKCSVSCGEGLQYRSLKCGYENENKTLTTWDNNEMCKNKMVPVSIQICKVTPCPKWIYSEWSECEGTCEYGSQHRTVLCTD---PISE-------QILPDSKCDIK------NKFP----------------------NFQKCLLSKLCG-HWIVGKWSQCSASCGLGVKTRTITCNYSNGSKSIDHSVCKSVA-PFEEIHCQVKPCSTNAFWWLVKPSECYEYNCQPGIMYAHVRCVNRKFQVLYDSKCSRIKHPSYYVGCLNTTC-RRYFWTAESWDNIPCPDISCTMKIRNRDVYCVDDYGNIQKDAMCDQSDKPDTWRLCPS 4167
            G F+  N  +F++P  K   N      + +  PH IY   LN    + L  C +         L  + Y N+ ++ +    RV     +   P+ D          I  P  IE+++   +  V     + + YIL+ ++I   +  DP+I   I I VV +V++  + E      D +       +  FC W + +  L +      D+A+LI  + + SS    N +G+++L ++C+   +C    ++G  + F IAHEL H +  +HD DN              TKY+ +M+ +L F   P+ WS CS+  +  FL + Y  CL  +       P E+I     +   G  YD N+QC  AFG  S+ C         C  L+C    K +  C       ADGT+C    HC +G C+ K     P++G W  +  +S+CSR C GG++ + R C+ P P +GG +C G + + RSCN + C   + D RE+ C  +N K      IP+N    P          C L C    TN+       + DGTPC     DICV+G C   GCD ++ S   ID C +C G N +C      F+ S      ++   +IP    N+ I++ S    P  D+ Y    D E   + N   ++  S+    + G +  + YSGS N VE I+   +    I I V+ V N    L  P + Y + +      D+F W         C   C G    +  C  K D+    D  C     P      C   C  RW     H I  +    C  +CG G   +   C K +  +      +TV+ +  +  D +  P +EL C G C    W Y +W +C   CG   R R   C +N G       C+    +   +E C  F    +   W  S WS C  +C    ++R V+C              L + + +SD FC+  S KP +  PC L++C  W     G C+  CG G++++  +C  +         ++D  C + +  +P D R  C L  C+  S                 W    W+ CSVSCG G Q R + C        L    +   C +   P  I  C  TPC +W   +WS C  +C +G   R VLC +   PI E       + L + +C +       + FP                      N  + +   + G  W  G W  CS+SC  G++ R + C   NG  +   S C + + P E   C   PC     W      EC +  C  GI    V C     Q+L D  C  +  P   + C    C     W  E W +      SC    + R+V+C+D +    +D  C Q  KP T + C S
Sbjct:  153 GTFKGQNGEYFLEPIMKADGNEY---EDGHNKPHLIYRQDLNNSFLQTLKYCSVSESQIKETSLPFHTYSNMNEDLNVMKERVLGHTSKNV-PLKDERRHSRKKRLISYPRYIEIMVTADAKVVSAHGSNLQNYILTLMSIVATIYKDPSIGNLIHIVVVKLVMIHREEEGPVINFDGAT-----TLKNFCSWQQTQNDLDDVHPSHHDTAVLITREDICSSKEKCNMLGLSYLGTICDPLQSCFINEEKGLISAFTIAHELGHTLGVQHD-DNPRCKEM------KVTKYH-VMAPALSFHMSPWSWSNCSRKYVTEFLDTGYGECLLDK-------PDEEIYNLPSELP-GSRYDGNKQCELAFGPGSQMCP----HINICMHLWCTSTEKLHKGCFTQHVPPADGTDCGPGMHCRHGLCVNKETETRPVNGEWGPWEPYSSCSRTCGGGIESATRRCNRPEPRNGGNYCVGRRMKFRSCNTDSCPKGTQDFREKQCSDFNGKHLDISGIPSNVRWLPRYSGIGTKDRCKLYCQVAGTNYFYLLKDMVEDGTPCGTETHDICVQGQCMAAGCDHVLNSSAKIDKCGVCGGDNSSCKTITGVFNSSHYGYNVVV---KIPAGATNVDIRQYSYSGQP--DDSYLALSDAEGNFLFNGNFLLSTSKKEINVQGTRTVIEYSGSNNAVERINSTNRQEKEILIEVLCVGN----LYNPDVHYSFNIPLEERSDMFTWDPYGPW-EGCTKMCQGLQRRNITCIHKSDHSVVSDKECDHLPLPSFVTQSCNTDCELRW-----HVIGKS---ECSSQCGQGYRTLDIHCMKYSIHEG-----QTVQVDDHYCGDQLKPPTQEL-CHGNCVFTRWHYSEWSQCSRSCGGGERSRESYCMNNFGHRLADNECQELSRV--TRENCNEF----SCPSWAASEWSECLVTCGKGTKQRQVWC-------------QLNV-DHLSDGFCN-SSTKPESLSPCELHTCASWQVGPWGPCTTTCGHGYQMRDVKCVNELAS----AVLEDTECHEAS--RPSD-RQSCVLTPCSFISKLETALLPTVLIKKMAQWRHGSWTPCSVSCGRGTQARYVSC-----RDALDRIADESYCAHLPRPAEIWDC-FTPCGEWQAGDWSPCSASCGHGKTTRQVLCMNYHQPIDENYCDPEVRPLMEQECSLAACPPAHSHFPSSPVQPSYYLSTNLPLTQKLEDNENQVVHPSVRGNQWRTGPWGSCSSSCSGGLQHRAVVCQDENGQSA---SYCDAASKPPELQQCGPGPCPQ---WNYGNWGECSQ-TCGGGIKSRLVICQFPNGQILEDHNCEIVNKPPSVIQCHMHACPADVSWHQEPWTSC---SASCGKGRKYREVFCIDQFQRKLEDTNCSQVQKPPTHKACRS 1471

HSP 2 Score: 166.777 bits (421), Expect = 7.107e-40
Identity = 214/863 (24.80%), Postives = 336/863 (38.93%), Query Frame = 1 
Query: 2209 SIVIKVENTKTTLNLPFISYHYFVKDIFVWKYLEVITHPCKDQCGGFIEISPACFKKRDNQRYVDHYCSKATKPEPKIIKCGAICGYRWQRATEHYINSTVNKSCPIRCGTGKVKIPFVCQKINNQDDNNSLWETVEENLCFAVDLVDRPIEELNC-VGQCNPLLWSYGKWEECPIECGTTFRYRNFICKDNKGLEWQKEWCERHLGLPDNKETCLSFNNCRNLTRWVTSPWSRCSNSCESELQKRMVYCFRSEKSDEILDEKFLKIHEQISDAFCDIHSPKPITERPCSLNSCYFWIXXXXXXXXXXXXLGFRIQSHECKKKFNKNHEMITVDDKFCLKQNLVKPLDVRMRCFLKKCAIESFWIEMEWSKCSVSCGEGLQYRSLKCGYENENKTLTTWDNNEMCKNKMVPVSIQICKVTPCPKWIYSEWSECEGTCEYGSQHRTVLCTDPISEQILPDSKCDIKNKFPNFQKCLLSKLCGHWIVGKWS-QCSASCGLGVKTRTITCNYSNGSKSIDHSVCKSVAPFEEIHCQVKPCSTNAFWWLVKPSECYEYNCQPGIMYAHVRCVN---------RKFQVLYDSKCSRIKHPSYYVGCLNTTCRRYFWTAESWDNIPCPDISCTMKIRNRDVYCVDDYGNIQKDAMCDQSDKPDTWRLCPSPQNCSNIPRSCKELKSRQSVSKDGEYSLAIDLNWAYFIYCADMNTEEPKEYLTL--RELNYARTSKYVSTDVSSCIYEEEMEFNQKCPTCKINENLWSITYYNKIRINLSDLSIDVMDDRFSATNGQSFIPFGTAKDCAGSTSCPKGHFKINLRGTGFSVSMETRWNEVYPKYGYRILRKQTSQIVKGWCGGHCSGCSP 4758
            S + K+E    T  LP +     +K +  W++      PC   CG   +      +   ++   + YC+   +P  +I  C   CG  WQ              C   CG GK     +C   +         + ++EN C   D   RP+ E  C +  C P   ++  +   P++        ++    N  L  + E  E  +  P  +             +W T PW  CS+SC   LQ R V C      DE             S ++CD  S KP   + C    C  W     G+CS  CG G + +   C+    +      ++D  C   N  KP  V ++C +  C  +  W +  W+ CS SCG+G +YR + C  + + K   T      C     P + + C+   CP W  + W+EC  TC  G Q R V C      Q++ +  CD   +  + ++C       H  + +    CS SC      + + C  +   +  +     S       +C+  PC  N        S+C   NC          C            + + +   +C  +     Y  C+N+      W    W       ++C + I  R V C+  +G +  D +C    KP   + C +  +C +   +CKE++ +  + KDG+Y L I       IYCADM  E PKEYLTL   E N++    +   +   C +      + +C    +       T ++KIRI+L+ + I   D  FS T   + +PF TA DC  +  CP+G F INL GTG  +S   +W          I R +      G CGG+C  C P
Sbjct: 1135 SFISKLE----TALLPTV----LIKKMAQWRHGSWT--PCSVSCGRGTQARYVSCRDALDRIADESYCAHLPRPA-EIWDCFTPCG-EWQAGDW--------SPCSASCGHGKTTRQVLCMNYH---------QPIDENYC---DPEVRPLMEQECSLAACPP---AHSHFPSSPVQ-------PSYYLSTNLPLTQKLEDNENQVVHPSVRGN-----------QWRTGPWGSCSSSCSGGLQHRAVVC-----QDE----------NGQSASYCDAAS-KPPELQQCGPGPCPQWNYGNWGECSQTCGGGIKSRLVICQFPNGQ-----ILEDHNCEIVN--KPPSV-IQCHMHACPADVSWHQEPWTSCSASCGKGRKYREVFCIDQFQRKLEDT-----NCSQVQKPPTHKACRSVRCPSWKANSWNECSVTCGSGVQQRDVYCRLKGVGQVV-EEMCDQSTRPCSQRRCWSQDCVQHKGMERGRLNCSTSCERKDSHQRMECTDNQIRQVNEIVYNSSTISLTSKNCRNPPC--NYIVVTADSSQCAN-NCGFSYRQRITYCTEIPSTKKHKLHRLRPIVYQECPVVPSSQVYQ-CINSCLHLATWKVGKWSKC---SVTCGIGIMKRQVKCITKHG-LSSD-LCLNHLKPGAQKKCYA-NDCKSF-TTCKEIQVKNHIRKDGDYYLNIK-GRIIKIYCADMYLENPKEYLTLVQGEENFSEVYGFRLKNPYQCPFNGSRREDCECDNGHLAAGY---TVFSKIRIDLTSMQIKTTDLLFSKTIFGNAVPFATAGDCYSAFRCPQGQFSINLSGTGMKISSTAKWLTQGSYTSVSIRRSEDGTRFFGKCGGYCGKCLP 1899

HSP 3 Score: 95.5153 bits (236), Expect = 3.750e-18
Identity = 144/575 (25.04%), Postives = 219/575 (38.09%), Query Frame = 1 
Query: 2656 PIEELNCVGQCNPLLWSYGKWEECPIECGTTFRYRNFIC--KDNKGLEWQKEWCERHLGLPD-NKETCLSFNNCRNLTRWVTSPWSRCSNSCESELQKRMVYCFRSEKSDEILDEKFLKIHE----QISDAFCDIHSPKPITERPCSLNSCYF--WIXXXXXXXXXXXXLGFRIQSHECKKKFNKNHEMITVDDKFCLKQNLVKPLDVRMRCFLKKCAIESFWIEMEWSKCSVSCGEGLQYRSLKCGYENENKTLTTWDNNEMCKNKMVPVSIQICKVTPCPKWIYSEWSECEGTCEYGSQHRTVLCTDPISEQILPDSKCDIKNKFPNFQKCLLS------------------KLCGHWIVGKWSQCSASCGLGVKTRTITCNYSNGSKSIDHSVCKSVAPFEEIHCQVKPCSTNAFWWLVKPSECYEYNCQPGIMYAHVRCVN-----------RKFQVLYDSKCSRIK-------------HPSYYVG---------------CLNTTCRRYFWTAESWDNIPCPDISCTMKIRNRDVYCVDDYGNIQKDAMCDQSDKPDTWRLC---PSPQ 4173
            P+EE + +   +P    YG WE C   C    + RN  C  K +  +   KE C+ HL LP    ++C    N     RW     S CS+ C    +   ++C +              IHE    Q+ D +C     KP T+  C  N C F  W  S+  +CS  CG G R +   C   F        + D  C + + V     R  C    C     W   EWS+C V+CG+G + R + C    ++ +      +  C +   P S+  C++  C  W    W  C  TC +G Q R V C + ++  +L D++C   ++  + Q C+L+                  K    W  G W+ CS SCG G + R ++C  +   +  D S C  +    EI     PC     W     S C   +C  G     V C+N            + + L + +CS                 PSYY+                 ++ + R   W    W +      SC+  +++R V C D+ G  Q  + CD + KP   + C   P PQ
Sbjct:  840 PLEERSDMFTWDP----YGPWEGCTKMC-QGLQRRNITCIHKSDHSVVSDKE-CD-HLPLPSFVTQSC----NTDCELRWHVIGKSECSSQCGQGYRTLDIHCMK------------YSIHEGQTVQVDDHYCG-DQLKPPTQELCHGN-CVFTRWHYSEWSQCSRSCGGGERSRESYCMNNFGHR-----LADNECQELSRV----TRENCNEFSCP---SWAASEWSECLVTCGKGTKQRQVWCQLNVDHLS------DGFCNSSTKPESLSPCELHTCASWQVGPWGPCTTTCGHGYQMRDVKCVNELASAVLEDTECHEASRPSDRQSCVLTPCSFISKLETALLPTVLIKKMAQWRHGSWTPCSVSCGRGTQARYVSCRDAL-DRIADESYCAHLPRPAEIWDCFTPCGE---WQAGDWSPC-SASCGHGKTTRQVLCMNYHQPIDENYCDPEVRPLMEQECSLAACPPAHSHFPSSPVQPSYYLSTNLPLTQKLEDNENQVVHPSVRGNQWRTGPWGSC---SSSCSGGLQHRAVVCQDENG--QSASYCDAASKPPELQQCGPGPCPQ 1361
[Close]
BLAST of A disintegrin and metalloproteinase with thrombospondin motifs vs. UniProt/SwissProt
Match: sp|Q9P2N4|ATS9_HUMAN (A disintegrin and metalloproteinase with thrombospondin motifs 9 OS=Homo sapiens OX=9606 GN=ADAMTS9 PE=1 SV=4)

HSP 1 Score: 359.377 bits (921), Expect = 2.038e-99
Identity = 334/1331 (25.09%), Postives = 530/1331 (39.82%), Query Frame = 1 
Query:  436 NGYRNIPQESHFSRVFQRMKRETYPVVDSEIVEPNIIELLIVVTSNFVKRFKKDFRQYILSNVAIATKLLHDPTIKASITXXXXXXXXXXEDYERNNDLHDWSLLSQDRVVSRFCHWVRQKKQLWNYSWDSAILINDGVF-----SSNAIGIAHLRSMCND-NNCLAVVDRGFGTGFIIAHELAHQMNARHDFDNAEACSFFEKQYDNKTKYNTIMSTSLFFEYYPFIWSVCSQNVINSFLKSKYSFCLKQRNRHRNLYPHEQINEFFQKYSTGVDYDLNEQCSFAFGEKSEFCETDQNSRKKCSVLYCRLKR--YPICLRADAIIADGTECDVNQHCINGKCLYKNITIAPIDGGWSEYSEWSNCSRPCNGGVQFSYRTCDNPVPADGGRFCTGTKERIRSCNIEEC-SSFSDPREESCGKYNLKPY----IPTNDEEFP----------CNLVCITTNHSLKYDI--SLTDGTPCSPFRSDICVKGTCYKTGCDRIVGSKKAIDNCNICAGQNDTCFKKESFFDGSKVAKVRMIRAFRIPPNVYNLFIKKVSQRMTPFTDEVYDDFELLLVVNRRTVIRRSETIEPLAGGQLR-------YSGSKNKVETIS----IKGKLNVGISIVIKVEN--TKTTLNLPF--ISYHYFVKDIFVWKYLEVITHPCKDQCGGFIEISPACFKKRDNQRYVDHYCSKATKPEPKIIKCGAICGYRWQRATEHYINSTVNKSCPIRCGTGKVKIPFVCQKINNQDDNNSLWETVEENLCFAVDLVDRPIEELNCVGQCNPLLWSYGKWEECPIECGTTFRYRNFICKDNKGLEWQKEWCERHLGLPDNKETCLSFNNCRNLTRWVTSPWSRCSNSCESELQKRMVYCFRSEKSDEILDEKFLKIHEQISDAFCDIHSPKPITERPCSLNSCYFWIXXXXXXXXXXXXLGFRIQSHECKKKFNKNHEMITVDDKFCLKQNLVKPLDVRMRCFLKKC---------------AIESFWIEMEWSKCSVSCGEGLQYRSLKCGYENENKTLTTWDNNEMCKNKMVPVSIQICKVTPCPKWIYSEWSECEGTCEYGSQHRTVLCTDPISEQILPDSKCDIKNKFPNFQKCLL---------SKLCGH------------------------WIVGKWSQCSASCGLGVKTRTITCNYSNGSKSIDHSVCKSVAPFEEIHCQVKPCSTNAFWWLVKPSECYEYNCQPGIMYAHVRCVNRKFQVLYDSKCSRIKHPSYYVGCLNTTC-RRYFWTAESWDNIPCPDISCTMKIRNRDVYCVDDYGNIQKDAMCDQSDKPDTWRLC 4161
            + Y N    +   R  +R KR         +  P  +E+L+V  +  V    ++ + YIL+ ++I   +  DP+I   I I +V+++++  +     D    S  +Q   +  FC W   K        D+A+L+            + +G+A L ++C+   +C    D G  T F IAHEL H  N  HD +N       + + +       +M+ +L F   P++WS CS+  I  FL + Y  CL      R  YP             G+ Y++N+QC   FG  S+ C        +C  L+C      +  C       ADGTEC+  +HC  G C+ K + +   DG W  +S +  CSR C GG++ + R C+ P P +GG++C G + + +SCN E C     D R+E C  ++ K +    +  N    P          C L C    ++  Y +   + DGTPC    +DICV+G C + GCD ++ SK   D C +C G N +C      F+        ++   RIP    N+ +++ S     F+ E  DD  L L  ++   +     +  +A  ++R       YSGS+  VE I+    I+ +L + +  V K+ N   + + N+P       ++      W+        C   C G  +    C ++ D     D  C +  +P      CG  C  RW  A+           C  +CG G   +   C K +  D      E V++  C +     +P     C G+CN   W Y  W EC   C    + R  IC + +        C     +    + C  F       +W +  WS C  +C    + R V+C   E              ++++D  CD  + KP + + C    C  W     G+CS  CG G+++++ +C         M  VDD  C      +P D +  C L  C               A  + W    W+ CS +CG+G + R + C   +EN ++    +   C     PV+ + C VTPC +W   +WS C  TC  G   R V+C +  S+ ++  S+CD        Q C +         S L  H                        W  G W  CS++C  G + R + C   NG  + D    + + P E+  C+  PC     W      EC +  C  GI    V C     +   D  C  +  P     C    C     W+   W +     +SC    + R+VYC+   G+  +   C    KP   R C
Sbjct:  267 SAYGNKTDNTREKRTHRRTKRF--------LSYPRFVEVLVVADNRMVSYHGENLQHYILTLMSIVASIYKDPSIGNLINIVIVNLIVIHNE----QDGPSISFNAQT-TLKNFCQWQHSKNSPGGIHHDTAVLLTRQDICRAHDKCDTLGLAELGTICDPYRSCSISEDSGLSTAFTIAHELGHVFNMPHDDNN-------KCKEEGVKSPQHVMAPTLNFYTNPWMWSKCSRKYITEFLDTGYGECLLNEPESRP-YP-------LPVQLPGILYNVNKQCELIFGPGSQVCPY----MMQCRRLWCNNVNGVHKGCRTQHTPWADGTECEPGKHCKYGFCVPKEMDVPVTDGSWGSWSPFGTCSRTCGGGIKTAIRECNRPEPKNGGKYCVGRRMKFKSCNTEPCLKQKRDFRDEQCAHFDGKHFNINGLLPNVRWVPKYSGILMKDRCKLFCRVAGNTAYYQLRDRVIDGTPCGQDTNDICVQGLCRQAGCDHVLNSKARRDKCGVCGGDNSSCKTVAGTFNTVHYGYNTVV---RIPAGATNIDVRQHS-----FSGETDDDNYLALSSSKGEFLLNGNFVVTMAKREIRIGNAVVEYSGSETAVERINSTDRIEQELLLQVLSVGKLYNPDVRYSFNIPIEDKPQQFYWNSHGPWQ-------ACSKPCQGERKRKLVCTRESDQLTVSDQRCDRLPQPGHITEPCGTDCDLRWHVASR--------SECSAQCGLGYRTLDIYCAKYSRLDGKT---EKVDDGFCSS---HPKPSNREKCSGECNTGGWRYSAWTECSKSCDGGTQRRRAICVNTRNDVLDDSKCTHQEKV--TIQRCSEF----PCPQWKSGDWSECLVTCGKGHKHRQVWCQFGE--------------DRLNDRMCDPET-KPTSMQTCQQPECASWQAGPWGQCSVTCGQGYQLRAVKCI----IGTYMSVVDDNDC--NAATRPTDTQ-DCELPSCHPPPAAPETRRSTYSAPRTQWRFGSWTPCSATCGKGTRMRYVSC--RDENGSVA---DESACATLPRPVAKEECSVTPCGQWKALDWSSCSVTCGQGRATRQVMCVN-YSDHVIDRSECDQDYIPETDQDCSMSPCPQRTPDSGLAQHPFQNEDYRPRSASPSRTHVLGGNQWRTGPWGACSSTCAGGSQRRVVVCQDENGYTAND--CVERIKPDEQRACESGPCPQ---WAYGNWGECTKL-CGGGIRTRLVVCQRSNGERFPDLSCEILDKPPDREQCNTHACPHDAAWSTGPWSSC---SVSCGRGHKQRNVYCMAKDGSHLESDYCKHLAKPHGHRKC 1493

HSP 2 Score: 206.453 bits (524), Expect = 5.962e-52
Identity = 199/802 (24.81%), Postives = 324/802 (40.40%), Query Frame = 1 
Query: 2521 CPIRCGTGKVKIPFVCQKINNQDDNNSLWETVEENLCFAVDLVDRPIEELNC-VGQCNPLLWSYGKWEECPIECGTTFRYRNFICKDNKGLEWQKEWCERHLGLPDNKETCLSFNNCRNLT-------------------------------RWVTSPWSRCSNSCESELQKRMVYCFRSEKSDEILDEKFLKIHEQISDAFCDIHSPKPITERPCSLNSCYFWIXXXXXXXXXXXXLGFRIQSHECKKKFNKNHEMITVDDKFCLKQNLVKPLDVRMRCFLKKCAIESFWIEMEWSKCSVSCGEGLQYRSLKCGYENENKTLTTWDNNEMCKNKMVPVSIQICKVTPCPKWIYSEWSECEGTCEYGSQHRTVLCTDPISEQILPDSKCDIKNKFPNFQKCLLSKLCGH-WIVGKWSQCSASCGLGVKTRTITCNYSNGSKSIDHSVCKSVAPFEEIHCQVKPCSTNAFWWLVKPSECYEYNCQPGIMYAHVRCV-------NRKFQVLYDSKCSRIKHPSYYVGCLNTTCRRYFWTAESWDNIPCPDISCTMKIRNRDVYCVDDYGNIQKDAMCDQSDKPDTWRLCPSPQNCSNIPRSCKELKSRQSVSKDGEYSLAIDLNWAYFIYCADMNTEEPKEYLTLRELNYARTSKYVSTDVSSCIYEEEMEFNQKCP---------TCKINENLWSITYYNKIRINLSDLSIDVMDDRFSATNGQSFIPFGTAKDCAGSTSCPKGHFKINLRGTGFSVSMETRWNEVYPKYGYRILRKQTSQIVKGWCGGHCSGCSPLKKFFVE 4779
            C   CG G       C+     D+N S+    +E+ C  +    RP+ +  C V  C    W    W  C + CG     R  +C +       +  C++   +P+  + C S + C   T                               +W T PW  CS++C    Q+R+V C          DE     ++ +          KP  +R C    C  W     G+C+  CG G R +   C++   +    ++        + L KP D R +C    C  ++ W    WS CSVSCG G + R++ C  ++ +        ++ CK+   P   + C+   CPKW    WS+C  +C  G Q R V C    + +I  +++C+   +  + + C   +   + W   +W +C+ +CG G + R + C   N ++        S  P +   C ++PC     W   + SEC    C  G     V C        N ++       C   + PS +   L        W   +W +     +SC + +  R V C+ +    Q   +C    KP+  + C +  NC  +P++CKE+K  +  S+DGEY L I       I+CA M+++ PKEY+TL   +    S+         +Y   +    +CP          C+ +      + + KIRI+L+ + I   D +F+ T+    +PF TA DC  +  CP+G F INL GTG S++   RW          I +      V G CGG+C  C+P     +E
Sbjct: 1194 CSATCGKGTRMRYVSCR-----DENGSV---ADESACATLP---RPVAKEECSVTPCG--QWKALDWSSCSVTCGQGRATRQVMCVNYSDHVIDRSECDQDY-IPETDQDC-SMSPCPQRTPDSGLAQHPFQNEDYRPRSASPSRTHVLGGNQWRTGPWGACSSTCAGGSQRRVVVC---------QDENGYTANDCVERI-------KPDEQRACESGPCPQWAYGNWGECTKLCGGGIRTRLVVCQRSNGERFPDLSC-------EILDKPPD-REQCNTHACPHDAAWSTGPWSSCSVSCGRGHKQRNVYCMAKDGSHL-----ESDYCKHLAKPHGHRKCRGGRCPKWKAGAWSQCSVSCGRGVQQRHVGCQIG-THKIARETECNPYTRPESERDCQGPRCPLYTWRAEEWQECTKTCGEGSRYRKVVCVDDNKNEVHGARCDVSKRPVDRESCSLQPC--EYVWITGEWSEC-SVTCGKGYKQRLVSCSEIYTGKENYEYSYQTTINCPGTQPPSVHPCYLRDCPVSATWRVGNWGSC---SVSCGVGVMQRSVQCLTN--EDQPSHLCHTDLKPEERKTCRNVYNC-ELPQNCKEVKRLKGASEDGEYFLMIRGK-LLKIFCAGMHSDHPKEYVTLVHGDSENFSE---------VYGHRLHNPTECPYNGSRRDDCQCRKDYTAAGFSSFQKIRIDLTSMQIITTDLQFARTSEGHPVPFATAGDCYSAAKCPQGRFSINLYGTGLSLTESARWISQGNYAVSDIKKSPDGTRVVGKCGGYCGKCTPSSGTGLE 1931

HSP 3 Score: 132.88 bits (333), Expect = 1.770e-29
Identity = 129/450 (28.67%), Postives = 188/450 (41.78%), Query Frame = 1 
Query: 2893 SPWSRCSNSCESELQKRMVYCFRSEKSDEILDEKFLKIHEQISDAFCD-IHSPKPITERPCSLNSCYFWIXXXXXXXXXXXXLGFRIQSHECKKKFNKNHEMITVDDKFCLKQNLVKPLDVRMRCFLKKCAIE---SFWIEMEWSKCSVSCGEGLQYRSLKCGYENENKTLTTWDNNEMCKNKMVPVSIQICKVTPCPKWIYSEWSECEGTCEYGSQHRTVLCTDPISEQILPDSKCDIKNKFPNFQKCLLSKLCGHWIVGKWSQCSASCGLGVKTRTITCNYSNGSKSIDHSVCKSVA-PFEEIHCQVKPC---------------STNAFWWLVKPSECYEYNCQPGIMYAHVRCVNRKFQVLYDSKCSRIKHPSYYVGCLNTTCRRYFWTAESWDNIPCPDISCTMKIRNRDVYCVDDYGNIQKDAMCDQSDKPDTWRLC---PSPQ 4173
             PW  CS  C+ E ++++V C R  +SD++           +SD  CD +  P  ITE PC  +    W  +   +CSA+CGLG+R     C K    + +   VDD FC      KP +       +KC+ E     W    W++CS SC  G Q R   C     N  L    ++  C ++   V+IQ C   PCP+W   +WSEC  TC  G +HR V C     E  L D  CD + K  + Q C   + C  W  G W QCS +CG G + R + C        +D + C +   P +   C++  C               +    W     + C    C  G    +V C +    V  +S C+ +  P     C  T C +  W A  W +     ++C      R V CV+   ++   + CDQ   P+T + C   P PQ
Sbjct:  885 GPWQACSKPCQGERKRKLV-CTR--ESDQLT----------VSDQRCDRLPQPGHITE-PCGTDCDLRWHVASRSECSAQCGLGYRTLDIYCAKYSRLDGKTEKVDDGFCSSH--PKPSN------REKCSGECNTGGWRYSAWTECSKSCDGGTQRRRAIC-VNTRNDVL----DDSKCTHQE-KVTIQRCSEFPCPQWKSGDWSECLVTCGKGHKHRQVWCQ--FGEDRLNDRMCDPETKPTSMQTCQQPE-CASWQAGPWGQCSVTCGQGYQLRAVKCIIGTYMSVVDDNDCNAATRPTDTQDCELPSCHPPPAAPETRRSTYSAPRTQWRFGSWTPC-SATCGKGTRMRYVSCRDENGSVADESACATLPRPVAKEECSVTPCGQ--WKALDWSSC---SVTCGQGRATRQVMCVNYSDHVIDRSECDQDYIPETDQDCSMSPCPQ 1297

HSP 4 Score: 126.331 bits (316), Expect = 1.438e-27
Identity = 114/415 (27.47%), Postives = 166/415 (40.00%), Query Frame = 1 
Query: 2518 SCPIRCGTGKVKIPFVCQKINNQDDNNSLWETVEENLCFAVDLVDR--PIEELNCVGQCNPLLWSYGKWEECPIECGTTFRYRNFICKDNKGLEWQKEWCERHLGLPDNKETCLSFNNCRNLTRWVTSPWSRCSNSCESELQKRMVYCFRSEKSDEILDEKFLKIHEQISDAFCDIHSPKPITERPCSLNSCYFWIXXXXXXXXXXXXLGFRIQSHECKKKFNKNHEMITVDDKFCLKQNLVKPL---DVRMRCFLKKCAIESFWIEMEWSKCSVSCGEGLQYRSLKCGYENENKTLTTWDNNEMCKNKMVPVSIQICKVTPCP-KWIYSEWSECEGTCEYGSQHRTVLCTDPIS--EQILPDSKCDIK---NKFPNFQKCLLSK--LCGHWIVGKWSQCSASCGLGVKTRTITC 3723
            +C   C  G  +   VCQ               +EN   A D V+R  P E+  C     P  W+YG W EC   CG   R R  +C+ + G  +    CE  L  P ++E C + + C +   W T PWS CS SC    ++R VYC   + S   L+  + K            H  KP   R C    C  W               +   S  C +   + H    +      ++    P    +    C   +C + + W   EW +C+ +CGEG +YR + C  +N+N+      +   C     PV  + C + PC   WI  EWSEC  TC  G + R V C++  +  E      +  I     + P+   C L    +   W VG W  CS SCG+GV  R++ C
Sbjct: 1339 ACSSTCAGGSQRRVVVCQ---------------DENGYTANDCVERIKPDEQRACESGPCPQ-WAYGNWGECTKLCGGGIRTRLVVCQRSNGERFPDLSCEI-LDKPPDREQC-NTHACPHDAAWSTGPWSSCSVSCGRGHKQRNVYCMAKDGSH--LESDYCK------------HLAKPHGHRKCRGGRCPKW-----------KAGAWSQCSVSCGRGVQQRHVGCQIGTHKIARETECNPYTRPESERDCQGPRCPLYT-WRAEEWQECTKTCGEGSRYRKVVCVDDNKNEV-----HGARCDVSKRPVDRESCSLQPCEYVWITGEWSECSVTCGKGYKQRLVSCSEIYTGKENYEYSYQTTINCPGTQPPSVHPCYLRDCPVSATWRVGNWGSCSVSCGVGVMQRSVQC 1704
[Close]
BLAST of A disintegrin and metalloproteinase with thrombospondin motifs vs. UniProt/SwissProt
Match: sp|Q19791|GON1_CAEEL (A disintegrin and metalloproteinase with thrombospondin motifs gon-1 OS=Caenorhabditis elegans OX=6239 GN=gon-1 PE=1 SV=3)

HSP 1 Score: 328.561 bits (841), Expect = 1.483e-89
Identity = 336/1299 (25.87%), Postives = 516/1299 (39.72%), Query Frame = 1 
Query:  544 IELLIVVTSNFVKRFKKDFRQYILSNVAIATKLLHDPTIKASITXXXXXXXXXXEDYERNNDLHDWSLLSQDRVVSRFCHWVRQKKQLWNYSWDSAILINDGVF------------SSNAIGIAHLRSMCN-DNNCLAVVDRGFGTGFIIAHELAHQMNARHDFDNAEACSFFEKQYDNKTKYNTIMSTSLFFEYYPFIWSVCSQNVINSFLKSK--YSFCLKQRNRHRNLYPHEQINEFFQKYSTGVDYDLNEQCSFAFGEKSEFCETDQNSRKK-CSVLY-----CRLKRYPICLRADAIIADGTECDVNQH--CINGKCL-YKNITIAPIDGGWSEYSEWSNCSRPCNGGVQFSYRTCDNPVPADGGRFCTGTKERIRSCNIEECSSFSDP-REESCGKYN-----LKPYIPTNDEEFP----------CNLVCITTNHSLKYDI--SLTDGTPCSPFRSDICVKGTCYKTGCDRIVGSKKAIDNCNICAGQNDTCFKKESFFDGSKVAKVRMIRAFRIPPNVYNLFIKKVSQRMTPFTDEVYDDFELLLVVNRRTVIRRSETIEPLAGGQ-------LRYSGSKNKVETISIKGKLNVGISI-VIKVENTKTTLNLPFISYHYFVKDI------------FVWKYLEVITHPCKDQCGGFIEISPACFKKRDNQRYVDHYCSKATKPEPKIIKCGAICGYRWQRATEHYINSTVNKSCPIRCGTGKVKIPFVCQKINNQDDNNSLWETVEENLCFAVDLVDRPIEELNCVGQCNPLLWSYGKWEECPIECGTTFR-YRNFICKDNKGLEWQKEWCERHLGLPDNKETCLSFNNCRNLTRWVTSPWSRCSNSCESELQKRMVYCFRSEKSDEILDEKFLKIHEQISDAFCDIHSPKPITERPCSLNSCYFWIXXXXXXXXXXXXLGFRIQSHECKKKFNKNHEMITVDDKFCLKQN--LVKPLDVRMRCFLKKCAIESFWIEMEWSKCSVSCGEGLQYRSLKCGYENENKTLTTWDNNEMCKNKM-VPVSIQICKVTPCPKWIYSEWSECEGTCEYGSQHRTVLCTDPISEQILPDSKCDIKNKFPNFQKCLLSKLCGHWIVGKWSQCSASCGLGVKTRTITCNYSNGSKSIDHSVC-KSVAPFEEIHCQVKPC-----------STNAFWWLVKPSECYEYNCQPGIMYAHVRCVNRKFQVLYDSKCSRIKHPSYYVGCLNTTCRRYFWTAESWDNIPCPDISCTMKIRNRDVYCV---DDYGNIQKDAMCDQSDKPDTWRLC---PSPQNCSNI 4188
            +E+L+V  +   +   +    Y+L+  +    +    +++ASI + VV +++L  +        +     QD     FC W    +Q +N   DS++  +D                 + +G+A L +MC+   +C  + D G    F IAHEL H  +  HD  +   CS +     NK  ++ IM+ +L +  +P+ WS CS  ++  FL++    + CL  +   R  Y      + F +   G  YD ++QC F FG  SE C      R+  C+  Y     CR +  P         ADGT CD ++   C +G C+     ++  IDG W ++  W  CSR C GGVQ   R CD+P P +GG++C G +ER RSCN +EC   + P RE  C ++N     ++    TN    P          C L C  +  +  Y +   + DGTPC     DICV G C   GCD  + S    D C +C G + +C   +  F+         +   +IP    N+ I     R   + +   DD  L L       +        LA  Q       L YSGS   +E I+  G +   I + V+ V +     + P ISY Y    +            ++W+  +  T  C   C G       C     +++  D  C    KP+     C   C  RW       I   V+ SC  +CG+G+ +    C K+              E+LC   D   +P +  +C   C+   W+YG+W  C   CG+  + +R   C D+      +  C R     + KE      N     RWV   WS CS SC+  ++ R   C         LD    + H                T+  C+ ++C +W       CSAKCG G + +   C  +    H  +  + + CLK    + KP      C  + C         EWS+CSVSC +G   R + C   N  +      +  +C      P S Q C +  CP W  ++WS C  +C  G + RT  C     EQ +  S C         Q C L   C  W    WS CS +CG G++TR+++C   +    +D   C ++  P  +  C+   C                 W   P       C  G     ++C +   + L D  C+ +        C    C   +W    W+   CP    T   ++R+V CV   D    I KD  CD   +P + R C   P P+   +I
Sbjct:  282 VEVLVVADTKMYEYHGRSLEDYVLTLFSTVASIYRHQSLRASINVVVVKLIVLKTENAGPRITQNAQQTLQD-----FCRW----QQYYNDPDDSSVQHHDVAILLTRKDICRSQGKCDTLGLAELGTMCDMQKSCAIIEDNGLSAAFTIAHELGHVFSIPHD--DERKCSTYMPV--NKNNFH-IMAPTLEYNTHPWSWSPCSAGMLERFLENNRGQTQCLFDQPVERRYY-----EDVFVRDEPGKKYDAHQQCKFVFGPASELCPYMPTCRRLWCATFYGSQMGCRTQHMPW--------ADGTPCDESRSMFCHHGACVRLAPESLTKIDGQWGDWRSWGECSRTCGGGVQKGLRDCDSPKPRNGGKYCVGQRERYRSCNTQECPWDTQPYREVQCSEFNNKDIGIQGVASTNTHWVPKYANVAPNERCKLYCRLSGSAAFYLLRDKVVDGTPCDRNGDDICVAGACMPAGCDHQLHSTLRRDKCGVCGGDDSSCKVVKGTFNEQGTFGYNEV--MKIPAGSANIDI-----RQKGYNNMKEDDNYLSLRAANGEFLLNGHFQVSLARQQIAFQDTVLEYSGSDAIIERINGTGPIRSDIYVHVLSVGS-----HPPDISYEYMTAAVPNAVIRPISSALYLWRVTDTWTE-CDRACRGQQSQKLMCLDMSTHRQSHDRNCQNVLKPKQATRMCNIDCSTRW-------ITEDVS-SCSAKCGSGQKRQRVSCVKMEGDRQT-----PASEHLC---DRNSKPSDIASCYIDCSGRKWNYGEWTSCSETCGSNGKMHRKSYCVDDSNRRVDESLCGR-----EQKEATERECNRIPCPRWVYGHWSECSRSCDGGVKMRHAQC---------LDAADRETHTS--------RCGPAQTQEHCNEHACTWWQFGVWSDCSAKCGDGVQYRDANCTDR----HRSVLPEHR-CLKMEKIITKP------CHRESCPKYKL---GEWSQCSVSCEDGWSSRRVSCVSGNGTEV-----DMSLCGTASDRPASHQTCNLGTCPFWRNTDWSACSVSCGIGHRERTTECI--YREQSVDASFCGDTKMPETSQTCHLLP-CTSWKPSHWSPCSVTCGSGIQTRSVSCTRGSEGTIVDEYFCDRNTRPRLKKTCEKDTCDGPRVLQKLQADVPPIRWATGPWTACSATCGNGTQRRLLKCRDH-VRDLPDEYCNHLDKEVSTRNCRLRDC--SYWKMAEWEE--CPATCGTHVQQSRNVTCVSAEDGGRTILKDVDCDVQKRPTSARNCRLEPCPKGEEHI 1475

HSP 2 Score: 168.703 bits (426), Expect = 1.989e-40
Identity = 138/508 (27.17%), Postives = 215/508 (42.32%), Query Frame = 1 
Query: 3295 WIEMEWSKCSVSCGEGLQYRSLKCGYENENKTLTTWDNNEMCKNKMVPVSIQICKVTPCPKWIYSEWSECEGTCEYGSQHRTVLCTDPISEQILPDSKCDIKNKFPNFQKCLLSKLCGH-WIVGKWSQCSASCGLGVK-TRTITCNYSNGSKSIDHSVCKSVAPFEEIHCQVKPCSTNAFWWLVKPSECYEYNCQPGIMYAHVRC-----VNRKFQVLY---------DSKCSRIKHPSYYVGC-LNTTCRRYFWTAESWDNIPCPDISCTMKIRNRDVYCVDDYGNIQKDAMCDQSDKPDTWRLCPSPQNCSNIPRSCKELKSRQSVSKDGEYSLAIDLNWAYFIYCADMNTEEPKEYLTLR-ELNYARTSKYVSTDVSSCIYEEEMEFNQKCPTCKINENLWSITYYNKIRINLSDLSIDVMDDRFSATNGQSFIPFGTAKDCAGSTSCPKGHFKINLRGTGFSVSMETRWNEVYPKYGYRILRKQTSQIVKGWCGGHCSGCSPLK 4764
            W    WS CS  CG G + R ++C   + N T+ + +    C     PV    C+   CP+W  + WS C  TC  G + R V C     + ++ DS+C+ K K  +   C       + W V  WS+C   C  G K TR + C  ++G ++       + AP     C    C    + W+    +    +C  G+    VRC      N    +++           KC     P+    C LN     + W+   W        +C   IR R V CV + G   +   C  + KP   + C   +NC  +P +C+ELKS+   +KDG Y++ +D  +   IYC  MN+  PK YL +    N+A           +C +  +   N  C   +  +    +T +NK+RI+L +    + D  F+       +P+GTA DC     CP+G F I+L+  G  +  +  W +   +   RI R   +  V G CGG C  CSP +
Sbjct: 1625 WQTSAWSACSAKCGRGTKRRVVECVNPSLNVTVASTE----CDQTKKPVEEVRCRTKHCPRWKTTTWSSCSVTCGRGIRRREVQCYRG-RKNLVSDSECNPKTKLNSVANCFPVACPAYRWNVTPWSKCKDECARGQKQTRRVHCISTSGKRAAPRMCELARAPTSIRECDTSNC---PYEWVPGDWQTCSKSCGEGVQTREVRCRRKINFNSTIPIIFMLEDEPAVPKEKCELFPKPNESQTCELNPCDSEFKWSFGPWGEC---SKNCGQGIRRRRVKCVANDGRRVERVKC-TTKKPRRTQYC-FERNC--LPSTCQELKSQNVKAKDGNYTILLD-GFTIEIYCHRMNSTIPKAYLNVNPRTNFAEVYGKKLIYPHTCPFNGDR--NDSCHCSEDGDASAGLTRFNKVRIDLLNRKFHLADYTFAKREYGVHVPYGTAGDCYSMKDCPQGIFSIDLKSAGLKLVDDLNWEDQGHRTSSRIDRFYNNAKVIGHCGGFCGKCSPER 2114

HSP 3 Score: 135.191 bits (339), Expect = 3.566e-30
Identity = 135/517 (26.11%), Postives = 212/517 (41.01%), Query Frame = 1 
Query: 2701 WSYGKWEECPIECGTTFRYRNFICKDNKGLEWQKEWC---ERHLGLPDNKETCLSFNNCRNLTRWVTSPWSRCSNSCESELQKRMVYCFRSEKSDEILDEKFLKIHEQISDAFCDIHSPKPITERPCSLNSCYFWIXXXXXXXXXXXXLGFRIQSHECKKKFNKNHEMITVDDKFCLKQNLVKPLDVRMRCFLKKCAIESFWIEMEWSKCSVSCGEGLQYRSLKCGYENENKTLTTW--DNN-----------EMCKNKMVPVSIQICKVTPCPKWIYSEWSECEGTCEYGSQHRTVLCTDPISEQILPDSKCDIKNKFPNFQKCLLSKLCGHWIVGKWSQCSASCGLGVK-TRTITC-NYSNGSKSIDHSVCKSVA--PFEEIHCQVKPCSTN----AFWWLVKPSECYEYNCQPGIMYAHVRCVNRKFQVLYDSKCSRIKHPSYYVGCLNTTCRRYFWTAESWDNIPCP--DISCTMKIRNRDVYCVDDY-GNIQKDAMCDQSDKPDTWRLCPSP 4170
            W +G W +C  +CG   +YR+  C D       +  C   E+ +  P ++E+C  +             WS+CS SCE     R V C     +             ++  + C   S +P + + C+L +C FW  +    CS  CG+G R ++ EC  +        +VD  FC      K  +    C L  C   + W    WS CSV+CG G+Q RS+ C   +E   +  +  D N           + C    V   +Q     P  +W    W+ C  TC  G+Q R + C D + +  LPD  C+  +K  + + C L + C +W + +W +C A+CG  V+ +R +TC +  +G ++I   V   V   P    +C+++PC         W +   S+C   +C  G     V C +        S C   + P  +  C    C     T  SW   P     +SC   ++ R ++C D   G  Q D  C +  KP   R C  P
Sbjct: 1117 WQFGVWSDCSAKCGDGVQYRDANCTDRHRSVLPEHRCLKMEKIITKPCHRESCPKYK---------LGEWSQCSVSCEDGWSSRRVSCVSGNGT-------------EVDMSLCGTASDRPASHQTCNLGTCPFWRNTDWSACSVSCGIGHRERTTECIYREQ------SVDASFC---GDTKMPETSQTCHLLPC---TSWKPSHWSPCSVTCGSGIQTRSVSCTRGSEGTIVDEYFCDRNTRPRLKKTCEKDTCDGPRVLQKLQA--DVPPIRWATGPWTACSATCGNGTQRRLLKCRDHVRD--LPDEYCNHLDKEVSTRNCRL-RDCSYWKMAEWEECPATCGTHVQQSRNVTCVSAEDGGRTILKDVDCDVQKRPTSARNCRLEPCPKGEEHIGSWIIGDWSKC-SASCGGGWRRRSVSCTS--------SSCDETRKPKMFDKCNEELCPPL--TNNSWQISPWTHCSVSCGGGVQRRKIWCEDVLSGRKQDDIECSEI-KPREQRDCEMP 1582

HSP 4 Score: 124.79 bits (312), Expect = 4.520e-27
Identity = 146/574 (25.44%), Postives = 218/574 (37.98%), Query Frame = 1 
Query: 2614 VEENLCFAVDLVDRPIEELNC-VGQCNPLLWSYGKWEECPIECGTTFRYRNFICKDNKGLEWQKEWCERHLGLPDNKETCLSFNNCRNLTRWVTSPWSRCSNSCESELQKRMVYCFRSEKSDEILDEKFLKIHEQISDAFCDIHSPKPITERPCSLNSC---------------YFWIXXXXXXXXXXXXLGFRIQSHECKKKFNKNHEMITVDDKFCLKQNLVKPLDVRMRCFLKKCAIESFWIEMEWSKCSVSCGEGLQY-RSLKC-GYENENKTLTTWDNNEMCKNKMVPVSIQICKVTPCPK-------WIYSEWSECEGTCEYGSQHRTVLCTDPISEQILPDSKCDIKNKFPNFQKCLLSKLC-----GHWIVGKWSQCSASCGLGVKTRTITCNYSNGSKSIDHSVCKSVAPFEEIHCQVKPCSTN----------------------------------AFWWLVKPSECYEYNCQPGIMYAHVRCVNRKFQV-LYDSKCSRIKHPSYYVGCLNTTCRRYFWTAESWDNIPCPDISCTMKIRNRDVYCVDDYGNIQKDAMCDQSDK 4140
            V+ +LC      DRP     C +G C    W    W  C + CG   R R   C   +       +C     +P+  +TC         T W  S WS CS +C S +Q R V C R  +   I+DE            FCD ++ +P  ++ C  ++C                 W       CSA CG G + +  +C+           + D++C   +L K +  R  C L+ C   S+W   EW +C  +CG  +Q  R++ C   E+  +T+     +  C  +  P S + C++ PCPK       WI  +WS+C  +C  G + R+V CT          S CD   K   F KC   +LC       W +  W+ CS SCG GV+ R I C      +  D   C  + P E+  C++ PC ++                                     W           C  G     V CVN    V +  ++C + K P   V C    C R  W   +W +     ++C   IR R+V C     N+  D+ C+   K
Sbjct: 1203 VDMSLCGTAS--DRPASHQTCNLGTCP--FWRNTDWSACSVSCGIGHRERTTECI-YREQSVDASFCG-DTKMPETSQTCHLLP----CTSWKPSHWSPCSVTCGSGIQTRSVSCTRGSEG-TIVDE-----------YFCDRNT-RPRLKKTCEKDTCDGPRVLQKLQADVPPIRWATGPWTACSATCGNGTQRRLLKCRDHVRD------LPDEYC--NHLDKEVSTR-NCRLRDC---SYWKMAEWEECPATCGTHVQQSRNVTCVSAEDGGRTIL---KDVDCDVQKRPTSARNCRLEPCPKGEEHIGSWIIGDWSKCSASCGGGWRRRSVSCTS---------SSCDETRKPKMFDKCN-EELCPPLTNNSWQISPWTHCSVSCGGGVQRRKIWCEDVLSGRKQDDIECSEIKPREQRDCEMPPCRSHYHNKTSSASMTSLSSSNSNTTSSASASSLPILPPVVSWQTSAWSACSAKCGRGTKRRVVECVNPSLNVTVASTECDQTKKPVEEVRCRTKHCPR--WKTTTWSSC---SVTCGRGIRRREVQCYRGRKNLVSDSECNPKTK 1723

HSP 5 Score: 103.99 bits (258), Expect = 1.034e-20
Identity = 122/514 (23.74%), Postives = 190/514 (36.96%), Query Frame = 1 
Query: 2692 PLLWSYGKWEECPIECGTTFRYRNFICKDNKGLEWQKEWCERHLGLPDNKETCLSFNNCR--NLTRWVTSPWSRCSNSCESELQK-RMVYCFRSEKSDEILDEKFLKIHEQISDAFCDIHSPKPITERPCSLNSC-------YFWIXXXXXXXXXXXXLGFRIQSHECKKKFNKNHEMITVDDKFCLKQNLVKPLDVRMRCFLKKCAIESFWIEMEWSKCSVSCGEGLQYRSLKCGYENENKTLTTWDNNEMCKNKMVPVSIQICKVTPCPK--------------------------------------WIYSEWSECEGTCEYGSQHRTVLCTDPISEQILPDSKCDIKNKFPNFQKCLLSKLCGHWIVGKWSQCSASCGLGVKTRTITCNYSNGSKSIDHSVCKSVAPFEEIHCQVKPCSTNAFWWLVKP-SECYEYNCQPGIMYAHVRCVNRKFQVLYDSKCSRIKHPSYYVGCLNTTCRRYFWTAESWDNIPCPDISCTMKIRNRDVYC 4086
            P+ W+ G W  C   CG   + R   C+D+   +   E+C  HL    +KE  +S  NCR  + + W  + W  C  +C + +Q+ R V C  +E     +          + D  CD+   +P + R C L  C         WI     KCSA CG G+R +S  C            + DK    + L  PL              + W    W+ CSVSCG G+Q R + C        L+    +++  +++ P   + C++ PC                                        W  S WS C   C  G++ R V C +P     +  ++CD   K     +C  +K C  W    WS CS +CG G++ R + C Y      +  S C        +     P +  A+ W V P S+C +   +       V C++   +      C   + P+    C  + C  Y W    W        SC   ++ R+V C
Sbjct: 1353 PIRWATGPWTACSATCGNGTQRRLLKCRDHV-RDLPDEYCN-HL----DKE--VSTRNCRLRDCSYWKMAEWEECPATCGTHVQQSRNVTCVSAEDGGRTI----------LKDVDCDVQK-RPTSARNCRLEPCPKGEEHIGSWIIGDWSKCSASCGGGWRRRSVSCTSSSCDETRKPKMFDK--CNEELCPPL------------TNNSWQISPWTHCSVSCGGGVQRRKIWC-----EDVLSGRKQDDIECSEIKPREQRDCEMPPCRSHYHNKTSSASMTSLSSSNSNTTSSASASSLPILPPVVSWQTSAWSACSAKCGRGTKRRVVECVNPSLNVTVASTECDQTKKPVEEVRC-RTKHCPRWKTTTWSSCSVTCGRGIRRREVQC-YRGRKNLVSDSECNPKTKLNSV-ANCFPVACPAYRWNVTPWSKCKDECARGQKQTRRVHCISTSGKRAAPRMCELARAPTSIRECDTSNC-PYEWVPGDWQTC---SKSCGEGVQTREVRC 1821

HSP 6 Score: 68.5514 bits (166), Expect = 5.772e-10
Identity = 78/297 (26.26%), Postives = 120/297 (40.40%), Query Frame = 1 
Query: 2518 SCPIRCGTGKVKIPFVCQKINNQDDNNSLWETVEENLCFAVDLVDRPIEELNCVGQCNPLLWSYGKWEECPIECGTTFRYRNFIC-KDNKGLEWQKEWCERHLGLPDNKETCL-SFNNCRNLT----RWVTSPWSRCSNSC-ESELQKRMVYCFRSEKSDEILDEKFLKIHEQISDAFCDIHSPKPITERPCSLNSC-YFWIXXXXXXXXXXXXLGFRIQSHECKKKFNKNHEMITV----DDKFCLKQ--NLVKPLDVRMRCFLKKCAIESFWIEMEWSKCSVSCGEGLQYRSLKC 3366
            +C  +CG G  +    C        N SL  TV    C   D   +P+EE+ C  +  P  W    W  C + CG   R R   C +  K L    E          N +T L S  NC  +     RW  +PWS+C + C   + Q R V+C  +               ++ +   C++ +  P + R C  ++C Y W+      CS  CG G + +   C++K N N  +  +    D+    K+   L    +    C L  C  E  W    W +CS +CG+G++ R +KC
Sbjct: 1632 ACSAKCGRGTKRRVVECV-------NPSLNVTVASTEC---DQTKKPVEEVRCRTKHCPR-WKTTTWSSCSVTCGRGIRRREVQCYRGRKNLVSDSEC---------NPKTKLNSVANCFPVACPAYRWNVTPWSKCKDECARGQKQTRRVHCISTSG-------------KRAAPRMCEL-ARAPTSIRECDTSNCPYEWVPGDWQTCSKSCGEGVQTREVRCRRKINFNSTIPIIFMLEDEPAVPKEKCELFPKPNESQTCELNPCDSEFKWSFGPWGECSKNCGQGIRRRRVKC 1894
[Close]
BLAST of A disintegrin and metalloproteinase with thrombospondin motifs vs. UniProt/SwissProt
Match: sp|Q8TE60|ATS18_HUMAN (A disintegrin and metalloproteinase with thrombospondin motifs 18 OS=Homo sapiens OX=9606 GN=ADAMTS18 PE=1 SV=3)

HSP 1 Score: 258.455 bits (659), Expect = 1.277e-68
Identity = 240/855 (28.07%), Postives = 361/855 (42.22%), Query Frame = 1 
Query:  544 IELLIVVTSNFV-KRFKKDFRQYILSNVAIATKLLHDPTIKASITXXXXXXXXXXEDYERNNDLHDWSLLSQDRVVSRFCHWVRQKKQLWNYSWDSAILINDGVFSS------NAIGIAHLRSMCND-NNCLAVVDRGFGTGFIIAHELAHQMNARHDFDNAEACSFFEKQYDNKTKYNTIMSTSLFFEYYPFIWSVCSQNVINSFLKSKYSFCLKQRNRHRNLYPHEQINEFFQKYSTGVDYDLNEQCSFAFGEKSEFCETDQNSRKKCSVLYCRLKRYPICLRADAIIADGTECDVNQHCINGKCL-YKNITIAPIDGGWSEYSEWSNCSRPCNGGVQFSYRTCDNPVPADGGRFCTGTKERIRSCNIEECSSFS-DPREESCGKYNLKPY---------IPTNDEEFPCNLVCITTNHSLKYDIS--LTDGTPCSPFRSDICVKGTCYKTGCDRIVGSKKAIDNCNICAGQNDTC-FKKESFFDGSKVAKVRMIRAFRIPPNVYNLFIKKVSQRMTPFTDEVYDDFELLLVVNRRTVIRRSETIE-----PLAGGQLRYSGSKNKVETISIKGKLNVGISIVIKVENTKTTLNLPFISYHYFVKDI------------FVWKYLEVITHPCKDQC-GGFIEISPACFKKRDNQRYVDHYCSKATKP--EPKIIKCGAI-CGYRWQRATEHYINSTVNKSCPIRCGTGKVKIPFVCQKINNQDDNNSLWETVEENLCFAVDLVDRPIEELNCVGQCNPLLWSYGKWEECPIECGTTFRYRNFICKDNKGLEWQKEWCERHLGLPDNKETCLSFNNCRNLTR--WVTSPWSRCSNSCESELQKRMVYCFRSEKS 2973
            +E L+V     V K  K +   YIL+ + + + L  D TI + I + VV ++LL+++       H       D+ ++ FC W            D AIL+      S      + +G A +  MC+   +C    D G G  F IAHE  H     HD +    C   E           IMS +L      F WS CS+  +  FL +  + CL    +    Y        +     G  YD + QC + FG K++ C      +  C  L+C    +  C       A+GT C ++  C  G+C+ +  +   PI G WS +S+WS CSR C GGV+F  R C+NP P  GG FC G+    + CNI  C+  S D R + C +YN KP+             +EE  C L C   N    + +S  + DGTPCSP ++D+C+ G C   GCD  +GSK   D C +C G N TC F K  + +  K  +   +    IP    ++ I+++         +V   +  +  ++++  +    +I+     P AG    Y  S N+ E +   G  N  +   I ++        P I++ Y +  +            + W    ++   C   C GG+I +   C + ++ Q     +CS  TKP  EPKI  C A  C   W         ST +K+C    G    KI  V +K   ++      E V  +LC     V  P +   C     P  WS G W +C   CG   R R  +CK +      +  C   L  P+ +E C+    C   +R  WV S WS CS +C   ++KR + C  SEK 
Sbjct:  295 VETLVVADKKMVEKHGKGNVTTYILTVMNMVSGLFKDGTIGSDINVVVVSLILLEQEPGGLLINHH-----ADQSLNSFCQWQSALIGKNGKRHDHAILLTGFDICSWKNEPCDTLGFAPISGMCSKYRSCTINEDTGLGLAFTIAHESGHNFGMIHDGE-GNPCRKAE---------GNIMSPTLTGNNGVFSWSSCSRQYLKKFLSTPQAGCLVDEPKQAGQYK-------YPDKLPGQIYDADTQCKWQFGAKAKLCSLG-FVKDICKSLWCHRVGH-RCETKFMPAAEGTVCGLSMWCRQGQCVKFGELGPRPIHGQWSAWSKWSECSRTCGGGVKFQERHCNNPKPQYGGLFCPGSSRIYQLCNINPCNENSLDFRAQQCAEYNSKPFRGWFYQWKPYTKVEEEDRCKLYCKAENFEFFFAMSGKVKDGTPCSPNKNDVCIDGVCELVGCDHELGSKAVSDACGVCKGDNSTCKFYKGLYLNQHKANEYYPV--VLIPAGARSIEIQEL---------QVSSSYLAVRSLSQKYYLTGGWSIDWPGEFPFAGTTFEYQRSFNRPERLYAPGPTNETLVFEILMQGKN-----PGIAWKYALPKVMNGTPPATKRPAYTW---SIVQSECSVSCGGGYINVKAICLRDQNTQ-VNSSFCSAKTKPVTEPKI--CNAFSCPAYWMPGEW----STCSKACAG--GQQSRKIQCVQKKPFQKE------EAVLHSLC----PVSTPTQVQACNSHACPPQWSLGPWSQCSKTCGRGVRKRELLCKGSAAETLPESQCTS-LPRPELQEGCV-LGRCPKNSRLQWVASSWSECSATCGLGVRKREMKC--SEKG 1083

HSP 2 Score: 88.9669 bits (219), Expect = 3.523e-16
Identity = 89/313 (28.43%), Postives = 131/313 (41.85%), Query Frame = 1 
Query: 3313 SKCSVSCGEGLQYRSLKCGYENENKTLTTWDNNEMCKNKMVPVS-IQICKVTPCPK-WIYSEWSECEGTCEYGSQHRTVLCTD--PIS-EQILPDSKCDIKNKFPNFQKCLLSKLCGHWIVGKWSQCSASCGLGVKTRTITCNYSNGSKSIDHSVCKSVA-PFEEIHCQVKPCSTNA-FWWLVKP-SECYEYNCQPGIMYAHVRCVNRKFQ----VLYDSKCSRIKHPSYYVGCLNTTCRRYFWTAE-------SWDNIPCPD--ISCTMKIRNRDVYCVDDYGNIQKDAMCDQSDKPDTWR-----LCPSPQ 4173
            S+CSVSCG G       C   ++N    T  N+  C  K  PV+  +IC    CP  W+  EWS C   C  G Q R + C    P   E+ +  S C +       Q C        W +G WSQCS +CG GV+ R + C  S  ++++  S C S+  P  +  C +  C  N+   W+    SEC    C  G+    ++C  + FQ       + +C  IK P+     L  TC R    A         W ++P     ++C   ++ R V+CV      +  + C    KP   R      CP+P+
Sbjct:  883 SECSVSCGGGYINVKAIC-LRDQN----TQVNSSFCSAKTKPVTEPKICNAFSCPAYWMPGEWSTCSKACAGGQQSRKIQCVQKKPFQKEEAVLHSLCPVSTPT-QVQACNSHACPPQWSLGPWSQCSKTCGRGVRKRELLCKGS-AAETLPESQCTSLPRPELQEGCVLGRCPKNSRLQWVASSWSEC-SATCGLGVRKREMKCSEKGFQGKLITFPERRCRNIKKPNLD---LEETCNRRACPAHPVYNMVAGWYSLPWQQCTVTCGGGVQTRSVHCVQQG---RPSSSCLLHQKPPVLRACNTNFCPAPE 1181

HSP 3 Score: 85.8853 bits (211), Expect = 2.969e-15
Identity = 70/259 (27.03%), Postives = 109/259 (42.08%), Query Frame = 1 
Query: 3202 VDDKFCLKQNLVKPLDVRMRCFLKKCAIESFWIEMEWSKCSVSCGEGLQYRSLKC----GYENENKTLTTWDNNEMCKNKMVPVSIQICKVTPCP-KWIYSEWSECEGTCEYGSQHRTVLCTDPISEQILPDSKCDIKNKFPNFQKCLL------SKLCGHWIVGKWSQCSASCGLGVKTRTITCN---YSNGSKSIDHSVCKSVAP----FEEI----HCQVKPCSTNAFWWLVKPSECYEYNCQPGIMYAHVRCVNR 3912
            V+  FC  +   KP+     C    C   ++W+  EWS CS +C  G Q R ++C     ++ E   L     + +C     P  +Q C    CP +W    WS+C  TC  G + R +LC    +E  LP+S+C    +    + C+L      S+L   W+   WS+CSA+CGLGV+ R + C+   +     +     C+++       EE      C   P       W   P +     C  G+    V CV +
Sbjct:  908 VNSSFCSAK--TKPVTEPKICNAFSCP--AYWMPGEWSTCSKACAGGQQSRKIQCVQKKPFQKEEAVL-----HSLCPVS-TPTQVQACNSHACPPQWSLGPWSQCSKTCGRGVRKRELLCKGSAAE-TLPESQCTSLPRPELQEGCVLGRCPKNSRL--QWVASSWSECSATCGLGVRKREMKCSEKGFQGKLITFPERRCRNIKKPNLDLEETCNRRACPAHPVYNMVAGWYSLPWQQCTVTCGGGVQTRSVHCVQQ 1153
[Close]
BLAST of A disintegrin and metalloproteinase with thrombospondin motifs vs. TrEMBL
Match: T1D158 (ADAMTS5 OS=Dendrocoelum lacteum OX=27895 PE=2 SV=1)

HSP 1 Score: 1530 bits (3960), Expect = 0.000e+0
Identity = 757/1539 (49.19%), Postives = 1035/1539 (67.25%), Query Frame = 1 
Query:  271 GVFQWDNKLWFIKPNTKTKFNSKFLKTEMNFLPHKIYFTALNLNKPLFSCKLLKNNGYRNIPQ-ESHFS-RVFQRMKRET--------YPVVDSEIVEPNIIELLIVVTSNFVKRFKKDFRQYILSNVAIATKLLHDPTIKASITXXXXXXXXXXEDYERNNDLHDWSLLSQDRVVSRFCHWVRQKKQLWNYSWDSAILINDGVFSSNAIGIAHLRSMCNDNNCLAVVDRGFGTGFIIAHELAHQMNARHDFDNAEACSFFEKQYDNKTKYNTIMSTSLFFEYYPFIWSVCSQNVINSFLKSKYSFCLKQRNRHRNLYPHEQINEFFQKYSTGVDYDLNEQCSFAFGEKSEFCETDQNSRKKCSVLYCRLKRYPICLRADAIIADGTECDVNQHCINGKCLYKNITIAPIDGGWSEYSEWSNCSRPCNGGVQFSYRTCDNPVPADGGRFCTGTKERIRSCNIEECSSFSDPREESCGKYNLKPYIPTNDEEFPCNLVCITTNHSLKYDISLTDGTPCSPFRSDICVKGTCYKTGCDRIVGSKKAIDNCNICAGQNDTCFKKESFFDGSKVAKVR-MIRAFRIPPNVYNLFIKKVSQRMTPFTDEVYDDFELLLVVNRRTVIRRSETIEPLAGGQLRYSGSKNKVETISIKGKLNVGISIVIKVENTKTTLNLPFISYHYFV--------KDIFVWKYLEVITHPCKDQCGGFIEISPACFKKRDNQRYVDHYCSKATKPEPKIIKCGAICGYRWQRATEHYINSTVNKSCPIRCGTGKVKIPFVCQKINNQDDNNSLWETVEENLCFAVDLVDRPIEELNCVGQCNPLLWSYGKWEECPIECGTTFRYRNFICKDNKGLEWQKEWCERHLGLPDNKETCLSFNNCRNLTRWVTSPWSRCSNSCESELQKRMVYCFRSEKSDE---ILDEKFLKIHEQISDAFCDIHSPKPITERPCSLNSCYFWIXXXXXXXXXXXXLGFRIQSHECKKKFNKNHEMITVDDKFCLKQNLVKPLDVRMRCFLKKCAIESFWIEMEWSKCSVSCGEGLQYRSLKCGYENENKTLTTW-DNNEMCKNKMVPVSIQICKVTPCPKWIYSEWSECEGTCEYGSQHRTVLCTDPISEQILPDSKCDIKNKFPNFQKCLLSKLCGHWIVGKWSQCSASCGLGVKTRTITCNYSNGSKSIDHSVCKSVAPFEEIHCQVKPCSTNAFWWLVKPSECYEYNCQPGIMYAHVRCVNRKFQVLYDSKCSRIKHPSYYVGCLNTTCRRYFWTAESWDNIPCPDISCTMKIRNRDVYCVDDYGNIQKDAMCDQSDKPDTWRLCPSPQNCSNIPRSCKELKSRQSVSKDGEYSLAIDLNWAYFIYCADMNTEEPKEYLTLRELNYARTSKYVST-DVSSCIYEEEMEFNQKCPTCKINENLWSITYYNKIRINLSDLSIDVMDDRFSATNGQSFIPFGTAKDCAGSTSCPKGHFKINLRGTGFSVSMETRWNEVYPKYGYRILRKQTSQIVKGWCGGHCSGCSPLKKFFVEPQMYGRDFEIKS 4815
            GVF W+NK +FIKP   ++ N+ +         H I++  ++  KPLFSCKLL++    +    ESH   ++ QR+KR          +P +D +++   +IELLIVVTSN VKRF    ++YILSN+AIATK+L DP+IK SI I+VVDI+ LD++YE+ + L +W LL+QD VV RFCHWVR  K+   YSWDSA+LINDG FS++AIGI HLRSMC  N+C+A+VDRGFGTG I+AHE+ HQ+NARHDF+   AC  FE+++  ++ YNT+MSTSL+FE YPFIWS CS+ +INS+LKS+ S+CLK++N    LY ++ I ++ + +STG+ YDLN QC+ AFGE S+ C ++++  K CS LYC  KR  +C+R+ +II+DGT CDV++ CI+G+CL  N  I PIDGGWSEY EWSNCSR CNGGVQFS R C+NP P  GGR+C GT+ R++SCNI +C    D R+E C ++N KPY+P  D++  C L+CI  N  L +++SL DGTPC   ++DICV   CYKTGCDR + S K  DNC IC G+NDTC   + FFDGSK++  R M+ AF+ P NV N+F++KVSQR++PF++EV+DDF+LLL+++  T+IRR E+IEP  GG+L YSGS  K ET  I G +   I ++I+ EN  T LN+P + YHY+V        ++ + WKY ++ +  C   C    EI   CFK ++N +  D  C    KP+ +I +C + C +RWQ+ T  +I     +SCP+RCG G + I  VCQK        ++WETV EN CF+  L+ RP    +CVG CNPL+WSYG WE C   CG+ FR R  ICKD  G  W +  C + LG    KE C+S   C+    W  S WS CS  C    Q R + C       E   IL EK     EQ+SD+FC   S KP+ ++ C  N CY W    S KCS  CG+G RI  + C K    N   ITV+DK+C +  + KP  +   C +  C  +  W+++ W KCS SCG+G++ R ++CGY+ + + +T W  N+  C+N+  P  ++ C+  PC    Y  WS C+GTC YG+Q RT+ C D  S++ILPDS C+  +K    +KCL++ LCGHW V  WS+CS SCGLG KTR ++C Y NGS+S D S+C++ +P +EI+C+   C + AFWWL+K S+CY Y C+PG+ Y+ +RCVN  FQ+L D  C  +KHP+YY  C+ + CR+YFW+AESW NIPC   SC M IRNR V CVD+YGN+  ++ CD++ + D WRLC SP+NCS++PRSCKELK R   ++DGEYSLAIDLNW YFI+C++M TE P EYLTL+  NYA+ S  +S  +  +C     M++   C  C+ +E L SITYYNK+R+N++DLSID+ D+++S T G +++P+GTAKDCAGS +CP+GHF ++L  T FSVSM+T WNE++  YGY+I+R + SQ+VKGWCGG CSGC+PL K ++EPQMYGRD E+KS
Sbjct:  116 GVFYWNNKEYFIKPAKPSENNNGYTNPGKFLSLHHIHYNEVSSKKPLFSCKLLEDEKASHYSSDESHQKPKLLQRVKRSIEYENDDNFFPFIDHDVIHDYVIELLIVVTSNMVKRFGDTLKEYILSNIAIATKMLRDPSIKTSIAINVVDIIPLDQEYEKMHYLDNWGLLTQDAVVERFCHWVRYWKRHSKYSWDSAVLINDGSFSTHAIGITHLRSMCAPNSCIAIVDRGFGTGLILAHEIGHQINARHDFEGIVACKEFERKH-GESMYNTMMSTSLYFENYPFIWSECSEKLINSYLKSEDSWCLKEQNEGPILYLNKHIYDYHKNFSTGLIYDLNAQCTLAFGEPSDHCNSEEHV-KTCSTLYCIPKRMGMCIRSQSIISDGTPCDVDKRCIHGECLEVNRNIEPIDGGWSEYHEWSNCSRLCNGGVQFSKRFCNNPSPQLGGRYCIGTRVRMKSCNIHDCDHEVDIRKEICKRFNAKPYVPRVDDDSVCRLICIKDNKVLLHNLSLVDGTPCYSHKTDICVNSKCYKTGCDRDLLSDKVFDNCRICGGKNDTCSIVKGFFDGSKISSSRSMMVAFKFPKNVTNVFVRKVSQRLSPFSEEVFDDFQLLLLIDHNTMIRRGESIEPFPGGELYYSGSNKKEETYRITGLIQKEIVVLIRTENPSTLLNIPSVDYHYYVPNQVRFSSQEEYSWKYSKINSSFCFGHCNAQFEIKSICFKNKENIQVSDTLCKSILKPKRQIKQCRSFCDFRWQKPTIKFIKLEAKQSCPVRCGNGSIIINHVCQKKTIMKPRQNVWETVPENHCFSSGLLKRPNTTNHCVGSCNPLIWSYGNWENCSKSCGSGFRKRTAICKDTDGRSWNEVECLKDLGGALEKEPCISKFTCKEDAYWAISNWSVCSKMCGLGTQTRDIACLLKNSLSELSAILTEKLFLNSEQVSDSFCLSFSDKPLIKKTCIGNECYQWNIKYSAKCSVTCGVGSRISDYICVKVGQSN---ITVEDKYCFENRIEKPKYLAKPCIMNAC-YQPKWLKLPWGKCSESCGKGMKLRLIRCGYKTK-RNMTIWLRNDAACRNESRPAVMEHCQNVPCSTLRYGPWSRCQGTCLYGNQQRTIECIDENSKKILPDSACESYSKLQKTRKCLVTALCGHWKVESWSKCSVSCGLGTKTRAVSCLYVNGSQSSDTSICQNASPIKEIYCENPICKSKAFWWLLKSSQCYAYGCKPGVTYSDIRCVNNAFQILPDYMCDDLKHPNYYAECIRSECRQYFWSAESWSNIPCSSNSCMMTIRNRQVTCVDEYGNVYGNSHCDEATRLDDWRLCASPRNCSDVPRSCKELKERHPETEDGEYSLAIDLNWTYFIFCSNMKTESPTEYLTLKRPNYAKASHLLSIPNNKTC-----MKYEDTCSDCRSDETLRSITYYNKVRLNMTDLSIDIYDNQYSTTIGSAYVPYGTAKDCAGSKTCPQGHFVVDLSATEFSVSMKTSWNELHNNYGYKIVRTKGSQVVKGWCGGECSGCNPLPKLYIEPQMYGRDLEVKS 1642
[Close]
BLAST of A disintegrin and metalloproteinase with thrombospondin motifs vs. TrEMBL
Match: A0A4E0RLR3 (A disintegrin and metalloproteinase with thrombospondin motifs 9 OS=Fasciola hepatica OX=6192 GN=D915_001571 PE=4 SV=1)

HSP 1 Score: 775.007 bits (2000), Expect = 0.000e+0
Identity = 525/1823 (28.80%), Postives = 802/1823 (43.99%), Query Frame = 1 
Query:  505 YPVVDSEIVEPNIIELLIVVTSNFVKRFKKDFRQYILSNVAIATKLLHDPTIKASITXXXXXXXXXXEDYERNNDLHDWSLLSQDRVVSRFCHWVRQKKQLWNYSWDSAILINDGVFSSNAIGIAHLRSMCN-DNNCLAVVDRGFGTGFIIAHELAHQMNARHDFDNAEACSFFE-----------------------------------KQYDNKTKYNTIMSTSLFFEYYPFIWSVCSQNVINSFLKSKYSFCLKQRNRHRNLYPHEQINEFFQKYSTGVDYDLNEQCSFAFGE-KSEFCETDQNSRKKCSVLYCRLKRYPICLRADAIIADGTECDVNQHCINGKCLYKNITIAPIDGGWSEYSEWSNCSRPCNGGVQFSYRTCDNPVPADGGRFCTGTKERIRSCNIEECSSFSDPREESCG----KYN--LKPYIPTNDEEFPCNLVCITTNHSLKYDISLTDGTPCSPFRSDICVKGTCYKTGCDRIVGSKKAIDNCNICAGQNDTCFKKESFFDGSKVAKVR-----MIRAFRIPPNVYNLFIKKVSQRMTPFTDEVYDDFELLLVVNRRTVIRRSETIEPLAGGQLRYSGSKNKVETISIKGKL--NVGISIVIKVENT--------------KTTLNLP--FIS-----------------YHYFVKDI------------------------------FVWKYLEVIT--HPCKDQCGGFIEISPACFKKRDNQRY---------VDHYCSKATKPEPKIIKCGAICGYRWQ-----RATEHYINSTVNKSCPIRCGTGKVKIPFVCQK----INNQDDNNSLWETVE--ENLCFAVDL--VDRPIEELNCVGQCNPLLWSYGKWEECPIECGTTFRYRNFICKDNKGLEWQKEWCERHLGLP---------------------------------------DNKETCLSFNN-CRNLTRWVTSPWSRCS-------NSCES-------------ELQKRMVYC-------------FRSEKSDEILDEKFLKIHEQISDAFCDIHSPKPITERPCSLNSCYFWIXXXXXXXXXXXXLGFR---------------------------------IQSHECKKKFNKNHEM-ITVDDKFCLKQNLVKPLD---------------VRMRCFLKKCAIE-SFWIEMEWSKCSVSCGEGLQYRSLKCGYENENKTLTTWDNN---------------------------EMCKNKMVPVSI--QICKVTPCPKWIYSEWSECEGTCEYGSQHRTVLCT-----------------DPISEQILPDS--------------------KCDIKNKFPNFQK-CLLSKLCGHWIVGKWSQCSASCGLGVKTRTITCNYSNGSK-------------------------SIDH-----------SVCKSVAPFEEIHCQVKPCSTN-AFWWLVKPSECYEYNCQPGIMYAHVRCVNRKFQVLYDSKCSRIKHPSYYVGCLNTTCRRYFWTAESWDNIPCPDISCTMKIRNRDVYCVDDYGNIQKDAMCDQSDKPDTWRLCPSPQNCSNIPRSCKELKSRQSVSKDGEYSLAIDLNWAYFIYCADMNTEEPKEYLTLRELNYARTSKYVSTDVSS--CIYEEEMEFNQK--------------------------------CPTCKINENLWSITYYNKIRINLSDLSIDVMDDRFSATNGQSFIPFGTAKDCAGSTSCPKGHFKINLRGTGFSVSMETRWNEVYPKYGYRILRKQTSQIVKGWCGGHCSGCSPLKKFFVE 4779
            YPV+  + VEP+ IELL+VVT    +RF +   +Y+LS +   + LL  P++K S+ + +VDI+ L+ +Y   ++L DWS   Q++V+SRFC WV + ++  +++WDSAIL+N G F S A+G+AH RSMCN +++CLAV+DRGFGTG+IIAHEL HQ+ A+HDF+    C   +                                   K+  +  + +TIMS +L+F+ +P  WS CS+  I+ FL++  + CL++ +    L+  + + +  +    G  + L++QC F      + FC         C  LYC+      CL  +A  A+G+EC  N+ CI G+C+  +     ++G W E+  WS CSR C GGV+FS R C+NP PA GG FC GT+ R+RSC I  C    + R+E C     +Y   L  Y+P   E   C+L C+ +  ++ + I L DGTPC   R DIC+KG C++TGCD ++GS +  D C +C G N TC K +  + G  V  +      +I A RIP  V N F++KVS R TP++ + YDD+ LL+     T IRR ET EP  G +L YSG++   E +SI G+L  +V I I ++   T              K+ LN P  FI+                  H  V  +                              FVW+  E+ +    C      + E  P      + Q++          D+ C+   +P P + +C   CG RW       +T+       + +C  RCG G+     +C++        D    +W   +  E  C    L    +    ++C G C P+ W    W +C   CG   R+R   C+D  G +W    C +    P                                       D  E C +FNN C +  +W +S WS C        + C S              +++R V C             F   +S +  D   ++       +   +  P+P + + C    CY W  +   KCS  CG G R                                 +   EC ++      + I+ D +    + + +PL                +++ C +++C+     W    WSKCSV CG G++ R   C  E + + L +  +N                           E+C    +P  I  + C   PCPKW+  +W  CEGTCEYG Q R + C                  DP    +   S                    +C      P  ++ CLLS  C +W  G WS CS SCG+GV+ R + C + NG+K                         +ID            + C    P +   C+ +PC+ N  FWW +  SEC    C+ G     +RC++     + +S C  ++ PS ++ C+   C+++ W AE W+  PCP   C  ++R R V+CVD  G    D++C    KPD WR+C  P  C+++P++C E+K R   + DG + + +  +    ++CADM T  P EY+ L  +NYART+ ++    +S  C Y+ +   +Q                                 CP C    NL S TYY K+R++++ +S+D+ D RF+ T G S +PF TAKDC GST CP+G F I+LRGTG  VS +T W          I R ++ Q++ G CGG C GC P  + ++E
Sbjct:  383 YPVLSFQYVEPHTIELLVVVTERMAQRFGRLINEYLLSLLTTVSSLLRHPSLKTSLQLKIVDIMQLERNYAIRHNLDDWSYSKQEQVMSRFCRWVNRLRRP-DFNWDSAILLNIGHFKSTALGVAHYRSMCNMESSCLAVLDRGFGTGYIIAHELGHQLGAKHDFEQNSDCEMADQTPSNEFMDNTGQEFGTNHGISVDDLSQSTHYWQPKESTDAVRRDTIMSGTLYFDNFPLRWSACSRQAIHVFLETNGASCLRREDMPSALHTADWLAKRSRDDLPGSMFSLDQQCQFVLKVYATRFC---GQMLPACRQLYCQDAENGACLPMEAAWAEGSECGENKWCIQGQCVSTSQKPVRVNGNWGEWGPWSACSRSCGGGVRFSERECNNPEPAHGGDFCQGTRTRMRSCAIHPCKQPINIRQELCDVIGHRYGRQLGAYLPKLGEASACSLTCLDSGQAVHHAIKLPDGTPCYSQRDDICIKGHCWETGCDGVLGSSQRFDQCRVCGGDNSTCMKIKGVYKGESVNSLGIQTRGLINALRIPSGVTNAFVRKVSPRTTPYSSDSYDDYMLLIFEELTTQIRRGETREPFVGAELYYSGTRRAEEIVSITGRLRKDVNIMIKLENTETTRPPPTVEYHYFVDKSQLNSPLYFIAEEEALLASELANRRAGRSHSTVTTVDMPVHQSSSPMTRSGTPKSKEVRTDKPRVYFVWRISELPSGCRTCAGNSTSYAECYPMVHDAAERQKFSDYDFYRPVADYLCANLPRPPPVVRRCADFCGVRWTAKPAPSSTDESSGRRTHGACSARCGMGQQAAIHICEEYIVPAEEPDKTKGIWRPAQLGERACVKAGLGATSKQPSFVSCEGTCEPVFWIATNWTKCSANCGQGERFRQIRCQDKSGRDWPLMECIQSAESPAHMEAITGIISAQEAQISLAKFAANGQHTVGQISMNLRLDVSEQCFAFNNECASQLQWSSSLWSECEPLNDEMRSVCRSIEQADSRKRITVVGMRQRQVSCQYSGSKLPGTLQAFSITRSLDTTDTWPIQPELCRKASLMGVIQPEPSSRQVCPRPICYRWGTAHLSKCSVTCGKGVRSATVPCERVTVDSSTVLHRDSPPEQSIAPWVEQVSLAECHQRLGYTPRIFISEDSQSIFVETVERPLQGSRLKQLMDLNLDHPIQLECLMERCSSTIPVWHTTAWSKCSVPCGTGIRRRQAICMLETQEQNLDSRPSNENAATGRLEAFATVVTVSRLKAEIADQELCHKHNLPKPIEEEACFEGPCPKWMPEDWGPCEGTCEYGIQQRKLRCVLDVLPSRGHPMSGHPQEDPSQTLLFSASQGRHRVRLHRSVQYMDVDVERCHTVGPQPVTKRLCLLSDGCPYWYRGDWSSCSVSCGIGVRGRQVECRFPNGTKYHASNVGLSRFHGEPSQYPVDRFERAIDELTQVIENRSPTTFCTLPKPVDSSSCKTRPCTQNQPFWWSLMVSECGSETCEVGRRQRVIRCLSSTLGPIDESSCRYLERPSNWIPCVPFRCKQFEWRAERWN--PCPR-ECGPRMRYRRVHCVDHLGEEYSDSLCPAHLKPDNWRVC--PDLCTSLPKNCLEVKQRYPGALDGVHQILLG-HVQIPVHCADMETANPSEYIILARVNYARTAAFMQPTSTSNHCPYDVQSFTHQASRKGKSGSSSLLDTTAEEIRRQLTTKEVSAANCPDCPFVPNLASATYYQKVRLDVNTMSVDIHDMRFAYTVGSSPVPFATAKDCFGSTLCPQGRFHIDLRGTGLRVSTKTHWEGSNDHVASHIHRSESRQVIVGRCGGKCVGCWPRPRLYLE 2195
[Close]
BLAST of A disintegrin and metalloproteinase with thrombospondin motifs vs. TrEMBL
Match: G4LXI4 (ADAMTS peptidase (M12 family) OS=Schistosoma mansoni OX=6183 GN=Smp_124500 PE=4 SV=1)

HSP 1 Score: 721.465 bits (1861), Expect = 0.000e+0
Identity = 514/1758 (29.24%), Postives = 771/1758 (43.86%), Query Frame = 1 
Query:  508 PVVDSEIVEPNIIELLIVVTSNFVKRFKKDFRQYILSNVAIATKLLHDPTIKASITXXXXXXXXXXEDYERNNDLHDWSLLSQDRVVSRFCHWVRQKKQLWNYSWDSAILINDGVFSSNAIGIAHLRSMCN-DNNCLAVVDRGFGTGFIIAHELAHQMNARHDFDNAEACSFFEK----------------------------QYDNKTKY-------------NTIMSTSLFFEYYPFIWSVCSQNVINSFLKSKYSFCLKQRNRHRNLYPHEQINEFFQKYSTGVDYDLNEQCSFAFG-EKSEFCETDQNSRKKCSVLYCRLKRYPICLRADAIIADGTECDVNQHCINGKCLYKNITIAPIDGGWSEYSEWSNCSRPCNGGVQFSYRTCDNPVPADGGRFCTGTKERIRSCNIEECSSFSDPREESCGKYN------LKPYIPTNDEEFPCNLVCITTNHSLKYDISLTDGTPCSPFRSDICVKGTCYKTGCDRIVGSKKAIDNCNICAGQNDTCFKKESFFDGSKVAKV-----RMIRAFRIPPNVYNLFIKKVSQRMTPFTDEVYDDFELLLVVNRRTVIRRSETIEPLAGGQLRYSGSKNKVETISIKGKLNVGISIVIKVENTKTTLNLPFISYHYFVKD--------------------------------IFVWKYLEVITHPCKDQ-------------------------------CGGFIEISPACFK--KRDNQR-----------YVDHYCSKATKPEPKIIKCGAICGYRWQR------ATEHYINSTVNKSCPIRCGTGKVKIPFVCQK----INNQDDNNSLWETVE--ENLCFAVDLVDRPIEE--LNCVGQCNPLLWSYGKWEECPIECGTTFRYRNFICKDNKGLEWQKEWCE-------RHLGLPDNKET--------------------------------CLSFNNCRNLTRWVTSPWSRCSNSCESELQKRMVYCFRSEKSDEILDEKFLKIHEQISDAFCDIHSPKPITERPCSLNSCYFWIXXXXXXXXXXXXLGFRIQSHECKKKFNKNHEMITVDDKFCLKQNLVKPLDV----RMRCFLKKCAIESFWIEMEWSKCSVSCGEGLQYRSLKC----------GYENEN----KTLTTWDNNEMCKN-----------------------------KMVPVSIQ--------ICKVTPC----PKWIYSEWSECEGTCEYGSQHRTVLCTDPISE------------QILPDSKCDIKN-----------KFPNFQKCLLSKLCGHWIVGKWSQCSASCGLGVKTRTITCNYSNGS-----------------------------KSIDHSV-----CKSVAPFEEIHCQVKPCS-TNAFWWLVKPSECYEYNCQPGIMYAHVRCVNRKFQVLYDSKCSRIKHPSYYVGCLNTTCRRYFWTAESWDNIPCPDISCTMKIRNRDVYCVDDYGNIQKDAMCDQSDKPDTWRLCPSPQNCSNIPRSCKELKSRQSVSKDGEYSLAIDLNWAYFIYCADMNTEEPKEYLTLRELNYARTSKYVST-----------------DVSSCIYE----------------EEMEFNQ-KCPTCKINENLWSITYYNKIRINLSDLSIDVMDDRFSATNGQSFIPFGTAKDCAGSTSCPKGHFKINLRGTGFSVSMETRWNEVYPKYGYRILRKQTSQIVKGWCGGHCSGCSPLKKFFVE 4779
            P++  + VEP+ +ELL+VVT    ++F     +Y+LS +   + LL  P++K SI ++VVDI+LLD  Y R ++L DWS   Q++V++RFC WV + +    Y+WDSAIL+N G F S A+G+AH RSMCN +++CLAV+DRGFGTG IIAHEL HQ+ A+HDF    +C   E+                            ++D +  Y             +TIMS +L+F+ +P  WS CS+  I+ F++S  + CL+  N     Y  E++         G  + LN+QC F      ++FC         C  LYC+   +  CL  +   A+GT C  ++ CI G+C+  N    P+ G W E+  WS CSR C GGVQFS R C+NP P +GG FC GT+ R+RSC  E C    + R+  C K +      L+ Y P   E   CNLVC+  +HS+ +  SL DGTPC   R DIC++G C++TGCD I+GS+   D C +C G N TC + +  F+G+ +         ++ A RIP  V N F++KVS R TP++ + YDDF LL+    +T IRR ET EP AG +L YSGS+++ E +SI G+LN  ++IVI+VEN+ TT +LP + Y YF+                                  +  +K ++ + HP ++                                C G +     C+    +D++R             D+ C+   KP     +C   CG RW         T + I      SC  RC  G   + +VC++       +D +  +W   +  E +C    L   P +   + C G C+P+ W    W EC   CG   R R   C+D  G  W    C         H   P    T                                C S + CRN   W T+ WS C       L ++M    R    D I D K L I++ I   + ++              SC             K  +  ++ S    ++       I ++  FC K +++  L      R  C   KC     W   + S CSV+CG G++   + C             NE     + +   DN++  +N                             +M+P+ +          C   PC    P W  + WS C  +C  G + R V+C                   I   S+ +I+              P  Q+  L   C  W    W +CS +CG+G+++R + C  SNG+                             ++I  S+     C    P ++I C  +PC+    FWW V  SEC    C+       ++C++ +   ++D+ C+ ++ P  +  C +  C+R+ W   SW    CPD +C  +++ R V CVDD GN   + +C  + KP    +CP+   CS+IP+SC+ELK R   + DG Y L I+ +  Y IYCADM +  P EY+TLR++NYA +S+++                   ++S  +Y+                  ME N   CP+C    +L S T+YNK+R+++  L + + D RFS T G S +P+GTAKDC  ST CP                                   Q SQ++ G CGGHC+GC P    F+E
Sbjct:  136 PILSFQYVEPHTVELLVVVTETMKQKFGLFIDEYLLSTMTTVSTLLRHPSLKNSIQLNVVDIILLDPVYARRHNLEDWSNSKQEQVMARFCKWVNRLRTP-TYTWDSAILLNVGHFKSTALGVAHYRSMCNRESSCLAVLDRGFGTGHIIAHELGHQLGAKHDFQLNSSCGLEEQDHHMADPPTRSSAHDLKLGTYPYYQSGDEWDYREDYRNSDVHQYEFVRRDTIMSGTLYFDQFPLRWSACSRQAIHLFIESNGANCLRYLNSETTFYSAEKLAHHSMDNRPGQIFSLNKQCEFVLKINGTQFC---GQMLPPCRQLYCQDSEHRSCLPMETAWAEGTPCGSSKWCIQGRCVSTNENPTPLHGNWGEWGSWSKCSRSCGGGVQFSERECNNPEPQNGGNFCHGTRTRMRSCGNEPCEKQLNIRQTLCDKIDGQYKGQLRAYFPKLGEPTSCNLVCLYNSHSVSHGFSLPDGTPCYALRDDICIQGKCWETGCDGILGSRLRFDRCRVCGGDNSTCEEIKGVFNGNTLTPPGTYPRGLMTAVRIPKGVTNAFVRKVSDRNTPYSSDSYDDFMLLIFEELKTQIRRGETHEPFAGAELYYSGSRSREEIVSITGRLNKDVNIVIRVENSHTTQSLPRVEYSYFIDKSQKNNSLYFIAESEARLAEDRINRRTGRSQNILSSYKTVDELIHPVQNNPNELDNRKIKNEKPQIYFVWRISELPTGCTTCAGNVTTPAECYPLVPKDSERSQFSQFDLLRPVADYLCASMPKPPSVFRRCSDYCGVRWSAKPMQTGKTSNGIYKFYTSSCSARCNEGHEAVEYVCEEYIVPAEQKDKSKGIWRVAQLGELVCHKAGLGKAPSQPAYVTCKGSCHPVYWILSNWTECNNSCGDGTRKRILYCQDEIGQNWPLNECMNYGESMIHHSKAPKQSITIHSAQEIILLYQQNNNFQVSFEHNLYIEQYNDCFSLSKCRNDINWSTTRWSEC-----EPLDEQMKSNCR--LVDNITDRKDL-INKIIGVRYRNV--------------SCIIENNDNYHNSLNKYIVTDQLTSGYFMRR-------IQLNLNFCRKASMLGELMEEPYGREACTQPKCY---RWGNGQMSACSVNCGRGVKQTRISCECIILKDDLDTSSNEKNIVLQGIHIVDNDKCMQNLQYMPRLFTDKTNGTIFVETVERRIDNDQEMIPLKVDNINEPVMLTCIEAPCDLRVPAWRTTSWSACSSSCGLGVRQRKVMCVVETQNANLHKRHSISYTSIFTTSRFNIEVVDSQICHNALLPMPTEQETCLEAPCPMWQAEDWQECSVNCGMGIRSRQVACRSSNGTVINVETINDNQTFYHNIESSHGNSLQYTIQTIKKSITTKRKCLGPRPIDKISCGTRPCTGLEVFWWPVASSECNITGCELAKRERIIKCLSPRRGPVHDTACNHLEKPLNWTICESFKCKRFEWRTGSWSQ--CPD-TCVSRMKYRQVKCVDDLGNEYSETLCPANLKPSNRGVCPNL--CSDIPKSCRELKYRYPSADDGTYQLLIEQSLVY-IYCADMESSNPSEYITLRQINYAASSEFLQPYPDLNWCPPVNQNASMFNISKNMYQPNSNLDSSKDIPESFLTSMEVNNVNCPSCPTVSSLVSKTFYNKVRLDIYSLEVKINDGRFSHTLGSSMMPYGTAKDCFSSTVCP-----------------------------------QDSQLIYGRCGGHCTGCWPQPGLFLE 1816
[Close]
BLAST of A disintegrin and metalloproteinase with thrombospondin motifs vs. TrEMBL
Match: A0A5K4F784 (Uncharacterized protein OS=Schistosoma mansoni OX=6183 PE=4 SV=1)

HSP 1 Score: 671.774 bits (1732), Expect = 0.000e+0
Identity = 523/1851 (28.25%), Postives = 777/1851 (41.98%), Query Frame = 1 
Query:  508 PVVDSEIVEPNIIELLIVVTSNFVKRFKKDFRQYILSNVAIATKLLHDPTIKASITXXXXXXXXXXEDYERNNDLHDWSLLSQDRVVSRFCHWVRQKKQLWNYSWDSAILINDGVFSSNAIGIAHLRSMCN-DNNCLAVVDRGFGTGFIIAHELAHQMNARHDFDNAEACSFFEK----------------------------QYDNKTKY-------------NTIMSTSLFFEYYPFIWSVCSQNVINSFLKSKYSFCLKQRNRHRNLYPHEQINEFFQKYSTGVDYDLNEQCSFAFG-EKSEFCETDQNSRKKCSVLYCRLKRYPICLRADAIIADGTECDVNQHCINGKCLYKNITIAPIDGGWSEYSEWSNCSRPCNGGVQFSYRTCDNPVPADGGRFCTGTKERIRSCNIEECSSFSDPREESCGKYN------LKPYIPTNDEEFPCNLVCITTNHSLKYDISLTDGTPCSPFRSDICVKGTCYKTGCDRIVGSKKAIDNCNICAGQNDTCFKKESFFDGSKVAKV-----RMIRAFRIPPNVYNLFIKKVSQRMTPFTDEVYDDFELLLVVNRRTVIRRSETIEPLAGGQLRYSGSKNKVETISIKGKLNVGISIVIKVENTKTTLNLPFISYHYFVKD--------------------------------IFVWKYLEVITHPCKDQ-------------------------------CGGFIEISPACFK--KRDNQR-----------YVDHYCSKATKPEPKIIKCGAICGYRWQR------ATEHYINSTVNKSCPIRCGTGKVKIPFVCQK----INNQDDNNSLWETVE--ENLCFAVDLVDRPIEE--LNCVGQCNPLLWSYGKWEECPIECGTTFRYRNFICKDNKGLEWQKEWCE-------RHLGLPDNKET--------------------------------CLSFNNCRNLTRWVTSPWSRCSNSCESELQKRMVYCFRSEKSDEILDEKFLKIHEQISDAFCDIHSPKPITERPCSLNSCYFWIXXXXXXXXXXXXLGFRIQSHECKKKFNKNHEMITVDDKFCLKQNLVKPLDV----RMRCFLKKCAIESFWIEMEWSKCSVSCGEGLQYRSLKC----------GYENEN----KTLTTWDNNEMCKN-----------------------------KMVPVSIQ--------ICKVTPC----PKWIYSEWSECEGTCEYGSQHRTVLCTDPISE------------QILPDSKCDIKN-----------KFPNFQKCLLSKLCGHWIVGKWSQCSASCGLGVKTRTITC-----------NYSNGSK-------SIDH--------SVCKSVAPFEEIHCQ--------VKPCSTN---AFWWLVKPSECYEYNCQPGIMYAHVRC------------VNRKFQVLYDSKCSRIKHPSYYVGCL--NTTCRRYFWTAESWDNIPCPDISCT--------------------MKIRNRDVYCVDDYGNIQKDAMCDQSDKPDTWRLCPS----------------PQNC----------------------------------------SNIPRSCKELKSRQSVSKDGEYSLAIDLNWAYFIYCADMNTEEPKEYLTLRELNYARTSKYVST-----------------DVSSCIYE----------------EEMEFNQ-KCPTCKINENLWSITYYNKIRINLSDLSIDVMDDRFSATNGQSFIPFGTAKDCAGSTSCPKGHFKINLRGTGFSVSMETRWNEVYPKYGY-RILRKQTSQIVKGWCGGHCSGCSPLKKFFVE 4779
            P++  + VEP+ +ELL+VVT    ++F     +Y+LS +   + LL  P++K SI ++VVDI+LLD  Y R ++L DWS   Q++V++RFC WV + +    Y+WDSAIL+N G F S A+G+AH RSMCN +++CLAV+DRGFGTG IIAHEL HQ+ A+HDF+   +C   E+                            ++D +  Y             +TIMS +L+F+ +P  WS CS+  I+ F++S  + CL+  N     Y  E++         G  + LN+QC F      ++FC         C  LYC+   +  CL  +   A+GT C  ++ CI G+C+  N    P+ G W E+  WS CSR C GGVQFS R C+NP P +GG FC GT+ R+RSC  E C    + R+  C K +      L+ Y P   E   CNLVC+  +HS+ +  SL DGTPC   R DIC++G C++TGCD I+GS+   D C +C G N TC + +  F+G+ +         ++ A RIP  V N F++KVS R TP++ + YDDF LL+    +T IRR ET EP AG +L YSGS+++ E +SI G+LN  ++IVI+VEN+ TT +LP + Y YF+                                  +  +K ++ + HP ++                                C G +     C+    +D++R             D+ C+   KP     +C   CG RW         T + I      SC  RC  G   + +VC++       +D +  +W   +  E +C    L   P +   + C G C+P+ W    W EC   CG   R R   C+D  G  W    C         H   P    T                                C S + CRN   W T+ WS C       L ++M    R    D I D K L I++ I   + ++              SC             K  +  ++ S    ++       I ++  FC K +++  L      R  C   KC     W   + S CSV+CG G++   + C             NE     + +   DN++  +N                             +M+P+ +          C   PC    P W  + WS C  +C  G + R V+C                   I   S+ +I+              P  Q+  L   C  W    W +C   C  G++ R I C           N+   S+       SI+H        S   ++   ++  C+         +PC  N    +W+  + S+C   NC  GI    V C            +N      ++ + S +    Y +  +  + T +R        D I C    CT                    +  R R + C+        D  C+  +KP  W +C S                P  C                                        S+IP+SC+ELK R   + DG Y L I+ +  Y IYCADM +  P EY+TLR++NYA +S+++                   ++S  +Y+                  ME N   CP+C    +L S T+YNK+R+++  L + + D RFS T G S +P+GTAKDC  ST CP+G F+I+LRGT F VS++TRW       G   I R Q SQ++ G CGGHC+GC P    F+E
Sbjct:  307 PILSFQYVEPHTVELLVVVTETMKQKFGLFIDEYLLSTMTTVSTLLRHPSLKNSIQLNVVDIILLDPVYARRHNLEDWSNSKQEQVMARFCKWVNRLRTP-TYTWDSAILLNVGHFKSTALGVAHYRSMCNRESSCLAVLDRGFGTGHIIAHELGHQLGAKHDFELNSSCGLEEQDHHMADPPTRSSAHDLKLGTYPYYQSGDEWDYREDYRNSDVHQYEFVRRDTIMSGTLYFDQFPLRWSACSRQAIHLFIESNGANCLRYLNSETTFYSAEKLAHHSMDNRPGQIFSLNKQCEFVLKINGTQFC---GQMLPPCRQLYCQDSEHRSCLPMETAWAEGTPCGSSKWCIQGRCVSTNENPTPLHGNWGEWGSWSKCSRSCGGGVQFSERECNNPEPQNGGNFCHGTRTRMRSCGNEPCEKQLNIRQTLCDKIDGQYKGQLRAYFPKLGEPTSCNLVCLYNSHSVSHGFSLPDGTPCYALRDDICIQGKCWETGCDGILGSRLRFDRCRVCGGDNSTCEEIKGVFNGNTLTPPGTYPRGLMTAVRIPKGVTNAFVRKVSDRNTPYSSDSYDDFMLLIFEELKTQIRRGETHEPFAGAELYYSGSRSREEIVSITGRLNKDVNIVIRVENSHTTQSLPRVEYSYFIDKSQKNNSLYFIAESEARLAEDRINRRTGRSQNILSSYKTVDELIHPVQNNPNELDNRKIKNEKPQIYFVWRISELPTGCTTCAGNVTTPAECYPLVPKDSERSQFSQFDLLRPVADYLCASMPKPPSVFRRCSDYCGVRWSAKPMQTGKTSNGIYKFYTSSCSARCNEGHEAVEYVCEEYIVPAEQKDKSKGIWRVAQLGELVCHKAGLGKAPSQPAYVTCKGSCHPVYWILSNWTECNNSCGDGTRKRILYCQDEIGQNWPLNECMNYGESMIHHSKAPKQSITIHSAQEIILLYQQNNNFQVSFEHNLYIEQYNDCFSLSKCRNDINWSTTRWSEC-----EPLDEQMKSNCR--LVDNITDRKDL-INKIIGVRYRNV--------------SCIIENNDNYHNSLNKYIVTDQLTSGYFMRR-------IQLNLNFCRKASMLGELMEEPYGREACTQPKCY---RWGNGQMSACSVNCGRGVKQTRISCECIILKDDLDTSSNEKNIVLQGIHIVDNDKCMQNLQYMPRLFTDKTNGTIFVETVERRIDNDQEMIPLKVDNINEPVMLTCIEAPCDLRVPAWRTTSWSACSSSCGLGVRQRKVMCVVETQNANLHKRHSISYTSIFTTSRFNIEVVDSQICHNALLPMPTEQETCLEAPCPMWQAEDWQECIGECEYGIQHRKIRCIIELTSSQQINNHLQKSEDDSSLRLSINHLDSSLIRRSRSVNIMDVDQERCRNAGAKPISERPCLINLSCPYWYKSEWSKC-SVNCGMGIRSRQVACRSSNGTVINVETINDNQTFYHNIESSHVNSLQYTIQTIKKSITTKRKCLGPRPIDKISCGTRPCTGLEVFWWPVASSECNITGCELAKRERIIKCLSPRRGPVHDTACNHLEKPLNWTICESFKCKRFEWRTGSWSQCPDTCVSRMKYRQVKCVDDLGNEYSETLCPANLKPSNRGVCPNLCSDIPKSCRELKYRYPSADDGTYQLLIEQSLVY-IYCADMESSNPSEYITLRQINYAASSEFLQPYPDLNWCPPVNQNASMFNISKNMYQPNSNLDSSKDIPESFLTSMEVNNVNCPSCPTVSSLVSKTFYNKVRLDIYSLEVKINDGRFSHTLGSSMMPYGTAKDCFSSTVCPQGKFQIDLRGTSFKVSVKTRWTSNQITNGVSHIHRLQDSQLIYGRCGGHCTGCWPQPGLFLE 2119
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BLAST of A disintegrin and metalloproteinase with thrombospondin motifs vs. TrEMBL
Match: A0A4Z2DIS5 (A disintegrin and metalloproteinase with thrombospondin motifs 5 OS=Schistosoma japonicum OX=6182 GN=EWB00_000485 PE=4 SV=1)

HSP 1 Score: 491.5 bits (1264), Expect = 4.981e-140
Identity = 324/935 (34.65%), Postives = 480/935 (51.34%), Query Frame = 1 
Query:  508 PVVDSEIVEPNIIELLIVVTSNFVKRFKKDFRQYILSNVAIATKLLHDPTIKASITXXXXXXXXXXEDYERNNDLHDWSLLSQDRVVSRFCHWVRQKKQLWNYSWDSAILINDGVFSSNAIGIAHLRSMCN-DNNCLAVVDRGFGTGFIIAHELAHQMNARHDFDNAEACSFFEK----------------------------QYDNKTKY------------NTIMSTSLFFEYYPFIWSVCSQNVINSFLKSKYSFCLKQRNRHRNLYPHEQINEFFQKYSTGVDYDLNEQCSFAFGEK-SEFCETDQNSRKKCSVLYCRLKRYPICLRADAIIADGTECDVNQHCINGKCLYKNITIAPIDGGWSEYSEWSNCSRPCNGGVQFSYRTCDNPVPADGGRFCTGTKERIRSCNIEECSSFSDPREESCGKYN------LKPYIPTNDEEFPCNLVCITTNHSLKYDISLTDGTPCSPFRSDICVKGTCYKTGCDRIVGSKKAIDNCNICAGQNDTCFKKESFFDGSKVAKVR-----MIRAFRIPPNVYNLFIKKVSQRMTPFTDEVYDDFELLLVVNRRTVIRRSETIEPLAGGQLRYSGSKNKVETISIKGKLNVGISIVIKVENTKTTLNLPFISYHYFVKDIFVWKYLEVITHPCKDQCGGFIEISPACF-KKRDNQRYVDHYCS-KATKPEPKIIKCGAICGYRWQRATEHYINSTVNKSCPIRCGT--GKVKIPFVCQKINNQDDNNS------LWETVEENLCFAVDLVDRPIEELN-CVGQCN--------PLLWSYGKWEE-----CPIECGTTFRYRNFICKDNKGLEWQKE-----WCERHLGLP-------DNKETCLSFNNCRNL---TRWVTSPWSRCSNSCESELQKRMVYCFRSEKSDEILDEKFLKI---HEQISDA 3027
            P++  + VEP+ +ELL+VVT    ++F     +Y+LS +   + LL  P++KAS  + +VDI+LLD  Y R ++L DW    Q++V++RFC WV + +    Y+WDSAIL+N G F S A+G+AH RSMCN +++CLAV+DRGFGTG IIAHEL HQ+ A+HDF+    C   E+                            ++D K  Y            +TIMS +L+F+ +P  WS CS+  I+SF++S  + CL+  N  +  Y  +++   +     G  + LN+QC F    K ++FC         C  LYC+   +  CL  +A  A+GT C  N+ CI G+C+  N    P+ G W E+  WS CSR C GGVQFS R C+NP P +GG FC GT+ R+RSC IE C    + R+  C K +      LK Y P   E   CNL+C+  +HS+ + ISL DGTPC   R DIC++G C++TGCD I+GS+   D+C +C G N TC + +  F+G+ +         +I A RIP  V N F++KVS R T ++ + YDDF LL+    +T IRR ET EP AG +L YSGS+++ E +SI G+LN  ++IVI+VEN+ TT +LP + Y YF            I    K+    FI  + A   ++R N+R      + K+ +   K+I        +WQ   + Y    +++  P  C T  G V  P  C  +  +D   S      L+  V + LC ++    RP      C   C         P+L S    +E     C   CG       ++C++      QK+     W    LG          +  T  ++  C+       WV S W+ C+NSC    +KR + C    + +  L+E    I   H+Q++++
Sbjct:  357 PILSFQYVEPHTVELLVVVTERMRRQFGPFINEYLLSTMTTVSTLLRHPSLKASFQLSIVDIILLDPVYARRHNLEDWLNSKQEQVMARFCKWVNRLRTP-TYTWDSAILLNVGHFKSTALGVAHYRSMCNPESSCLAVLDRGFGTGHIIAHELGHQLGAKHDFELNSDCGLEEQNHHVVDTPTWSNTHDLKLGTYPYYQGDDEWDYKESYRNSVHQYEFIRRDTIMSGTLYFDQFPLRWSACSRQAIHSFVESNAANCLRHTNADKTFYSVKKLASHYVDNRPGKIFSLNQQCEFVLKNKGTQFC---GQMLPVCRQLYCQDSEHRSCLPMEAAWAEGTPCGDNKWCIQGQCISVNENPTPLHGSWGEWGSWSQCSRSCGGGVQFSERECNNPEPRNGGDFCHGTRTRMRSCGIEPCEKQLNIRQMLCDKIDGYYKGQLKAYFPKLGEPTSCNLICLHNSHSVPHTISLPDGTPCYAQRDDICIQGKCWETGCDGILGSRLRFDHCRVCGGDNSTCEEIKGVFNGNTLTPPGTYPRGLITAVRIPRGVTNAFVRKVSDRNTAYSSDSYDDFMLLIFEELKTQIRRGETREPFAGAELYYSGSRSREEIVSITGRLNKDVNIVIRVENSHTTQSLPRVEYSYF------------IDKSQKNNSLYFIAENEARLAEERINRRTGRSQNTFKSLETSEKLINSVKSSPGKWQDKPQVYFVWRISE-LPTGCTTCAGNVTTPAECYPLVPKDSERSQFSQFDLFRPVADYLCASMP---RPPPVFRRCSDYCGVRWSAKPVPILKSSNNIQEFHTSSCSARCGEGREAVMYVCEEYIIPAEQKDKSKGIWRAAQLGELVCYKAGLGSAPTQPAYITCKGTCHPVHWVLSNWTECTNSCGDGKRKRTLSCQDEIEQNWPLNECIQHIESTHQQLNNS 1271

HSP 2 Score: 306.605 bits (784), Expect = 2.717e-80
Identity = 198/628 (31.53%), Postives = 294/628 (46.82%), Query Frame = 1 
Query: 3295 WIEMEWSKCSVSCGEGLQYRSLKCGYENENKTLTTWD------------------NNEMCKNKMVPVSIQ--ICKVTPCPKWIYSEWSECEGTCEYGSQHRTVLC---------------------TDPISEQI---------------------LPDSKCDIKNKFPNFQK-CLLSKLCGHWIVGKWSQCSASCGLGVKTRTITCNYSNGS----------------------KSIDHSV------------CKSVAPFEEIHCQVKPCS-TNAFWWLVKPSECYEYNCQPGIMYAHVRCVNRKFQVLYDSKCSRIKHPSYYVGCLNTTCRRYFWTAESWDNIPCPDISCTMKIRNRDVYCVDDYGNIQKDAMCDQSDKPDTWRLCPSPQNCSNIPRSCKELKSRQSVSKDGEYSLAIDLNWAYFIYCADMNTEEPKEYLTLRELNYARTSKYV------------------------------STDVSSCIYEE---EMEFNQ-KCPTCKINENLWSITYYNKIRINLSDLSIDVMDDRFSATNGQSFIPFGTAKDCAGSTSCPKGHFKINLRGTGFSVSMETRWNEVYPKYGY-RILRKQTSQIVKGWCGGHCSGCSPLKKFFVE 4779
            W    WS CS SCG G++ R + C  E  N  L                      ++++C   ++P+  +   C   PCP W   EW +C G CEYG Q+R V C                     TD  S ++                     + + +C      P  +K CLL+  C +W   +WS CS +CG+G++ R + C + NG+                       S+ H +            C+   P ++I C+ +PC+ T  FWW V  SEC    C+       ++C+N K   ++DS C+ ++ P  +  C    C+R+ W+  SW    CP+ +C +++RNR V CVDD GN   + +C  + KP+   LCP+   CS++P+SC ELK R   + DG Y L I+ N+  +IYC +MNT  P EY+ LR++NYA +S+++                              + D S+ I E     ME N   CP C    NL S T+Y+KIR+++  L + + D RFS T G S +P+GTAKDC  ST CP+G F+I+LRGT F VS++T+W       G   I R Q  Q++ G CGG C+GC P    F+E
Sbjct: 1548 WRTTSWSACSSSCGLGIRLRQVMCVLETHNANLNKHHSVSYTSIFTASQSDVEVVDSQICNAALLPMPTEQETCLEAPCPVWRAEEWQDCIGECEYGIQYRHVRCVIELTSLQKISKHLQTSENDDTDDDSLRLSLNNPDSSSLIRRSRSANIMDVDEERCRNAGPKPISEKPCLLNNSCPYWHKSEWSSCSVNCGMGIRLRQVDCRFINGTVIDVEALNNNQTTYYNMEALHVNSLQHVIQTIKKGSTIRNKCQGPRPIDKIPCRTRPCTGTEVFWWPVTSSECNVTRCEMIKRERIIKCINPKLGPIHDSACNHLEKPLNWTICELFKCKRFKWSTGSWS--LCPN-TCELRMRNRQVKCVDDLGNEYSENLCPANLKPNNRALCPNL--CSDVPKSCWELKLRYPSADDGTYQLLIE-NYLVYIYCGNMNTSNPLEYINLRQINYAGSSEFLQPYPDSKWCPSINENNSLLHASENIYHIHSNIDSSNDITESLLTNMEVNTINCPKCPTVSNLASKTFYHKIRLDIYSLGVKIDDTRFSHTIGSSIMPYGTAKDCFSSTICPQGQFQIDLRGTNFKVSVKTQWTVNKHSDGVSHIHRLQDGQLIYGRCGGQCTGCWPQSGLFLE 2169
[Close]
BLAST of A disintegrin and metalloproteinase with thrombospondin motifs vs. Ensembl Cavefish
Match: ADAMTS20 (ADAM metallopeptidase with thrombospondin type 1 motif 20 [Source:HGNC Symbol;Acc:HGNC:17178])

HSP 1 Score: 444.121 bits (1141), Expect = 1.372e-128
Identity = 408/1600 (25.50%), Postives = 629/1600 (39.31%), Query Frame = 1 
Query:  535 PNIIELLIVVTSNFVKRFKKDFRQYILSNVAIATKLLHDPTIKASITXXXXXXXXXXEDYERNN-DLHDWSLLSQDRVVSRFCHWVRQKKQLWNYS---WDSAILIND-----GVFSSNAIGIAHLRSMCND-NNCLAVVDRGFGTGFIIAHELAHQMNARHDFDNAEACSFFEKQYDNKTKYNTIMSTSLFFEYYPFIWSVCSQNVINSFLKSKYSFCLKQRNRHRNLYPHEQINEFFQKYSTGVDYDLNEQCSFAFGEKSEFCETDQNSRKKCSVLYCRLKR--YPICLRADAIIADGTECDVNQHCINGKCLYKNITIAPIDGGWSEYSEWSNCSRPCNGGVQFSYRTCDNPVPADGGRFCTGTKERIRSCNIEECS-SFSDPREESCGKYNLKPY----IPTNDEEFP----------CNLVCITTNHSLKYDI--SLTDGTPCSPFRSDICVKGTCYKTGCDRIVGSKKAIDNCNICAGQNDTCFKKESFFDGSKVAKVRMIRAFRIPPNVYNLFIKKVSQRMTPFTDE--VYDDFELLLVVNRRTVIRRSETIEPLAGGQLRYSGSKNKVETISIKGKLNVGISIVIKVENTKTTLNLPFISYHYFV-----KDIFVWKYLEVITHPCKDQCGGFIEISPACFKKRDNQRYVDHYCSKATKPEPKIIKCGAICGYRWQRATEHYINSTVNKSCPIRCGTGKVKIPFVCQKINNQDDNNSLWETVEENLCFAVDLVDRPIEELNCVGQCNPLLWSYGKWE----------------------------------------------ECPIECGTTFRYRNFICKDNK-GLEWQKEWCERHLGLPDNKE--------------TCLSFNNCRNLTRWVTSPWSRCSNSCESELQKRMVYCFRSEKSDEILDEKFLKIHEQISDAFCDIHSPKPITERPCSLNSCYFWIXXXXXXXXXXXXLGFRIQSHECKKKFNKNHEMITVDDKFCLKQNLVKPLDVRMRCFLKKC------------------------------AIESFWIEMEWSKCSVSCGEGLQYRSLKCGYENENKTLTTWDNNEMCKNKMVPVSIQICKVTPCPKWIYSEWSECEGTCEYGSQHRTVLCTDPISEQILPDSKCDIKNKFPNFQKCLLSKLCG--HWIVGKWSQCSASCGLGVKTRTITCNYSNGSKSIDHSVCKSVAPFEEIHCQVKPCSTNAFWWLVKPSECYEYNCQPGIMYAHVRCVNRKFQVLYDSKCSRIKHPSYYVGCLNTTCRRYFWTAESWDNIPCPDISCTMKIRNRDVYCVDDYGNIQKDAMCDQSDKPDTWRLCPSPQ--------------------------NCSNIP------------------------------RSCKELKSRQSVSKDGEYSLAIDLNWAYFIYCADMNTEEPKEYLTLREL---NYARTSKYVSTDVSSCIYEEEMEFNQKCPTCKINENLWSITYYNKIRINLSDLSIDVMDDRFSATNGQSFIPFGTAKDCAGSTSCPKGHFKINLRGTGFSVSMETRW----NEVYPKYGYRILRKQTSQIVKGWCGGHCSGCSP 4758
            P  +EL++   +  V+   ++   YIL+ +++   +  DP++   I I +V ++++  + E  N + +  + L        FC W +    L +      D+A+LI            + +G+A L +MC+   +C    + G  + F IAHEL H  N  HD DN +      ++   K +Y+ +M+ +L ++  P+ WS CS+  I  FL + Y  CL          P  +  +   K   G  Y++N QC   FG  S+ C       K+C  L+C      +  C      +ADGT+C    +C +G C+ K I   P+ G W  +  +S CSR C GG + + R C+ P P +GGRFC G + + RSCN E C     D REE C  ++ K +    +P      P          C L C        Y +   + DGTPC P   DICV+G C + GCD ++ SK   D C +C G N +C      F+ ++     ++   RIP    N+ IK+VS   TP  D      D     ++N   V+   +      G ++ YSGS   VE I+   ++     ++++V    +  N P + Y + +     ++ FVW         C   C G       C +K D+    D  C    +P      C   C  RW  A +          C  +CG G   +  +C +        S+ E VE   C   DL  +P    +C G C    W Y  W                                               +CP+ CG  ++ R   C     G     + C       D++E              T       + LT+W    W+ CS SC    + R V C  ++    + DE +              H P+P     C  + C  W + +   CS  CG+G   +   C    N N +   VD+ +C      KP      C    C                              + ++ W    W  CS +C  G Q R + C  ++E ++         C  ++ P   + C   PCP W Y  W EC  +C  G + R V+C  P + Q L +  CD+ +K P+ ++C +    G   W    W  CS +CG G + R + C Y N +++++ +      P     C+V+PC T    W     +    +C  G+    V C  +    + + +C     PS    C+   C  Y W+A  W      + SC   IR+R   CVD       D++CD S +P  +  C S                            +CS +P                               SC+EL+ R+ + KDGE+ L++   +   IYCA+M T  PKEY+TLR     NY+    Y   +   C Y       Q C  C+ +      T ++++R++LS + I   D +FS T     +PF TA DC  +  CP+G F INL GTG  V+  T+W    N V  K G RI          G CGG C  C P
Sbjct:  273 PRFVELMVTADAKMVRHHGRNLEHYILTIMSVVAAVYKDPSVGNLINIMIVKLIVIHNEQEGPNVNFYAATTLHN------FCVWQQSHNVLDDSHPSHHDTALLITREDICRAKDKCDTLGLAELGTMCDPYRSCSISEENGLSSAFTIAHELGHVFNMPHD-DNPKC-----REAGIKHQYH-VMAPTLNYDTSPWSWSKCSRKYITEFLDTGYGECLLDE-------PVGKTYDLPVKLP-GQLYNVNRQCELMFGPGSQVCPF----MKQCKRLWCTSAEGDHKGCRTQHMPLADGTDCGHGMYCKHGMCVNKEIESRPVHGEWGPWGPYSVCSRTCGGGTRSTSRDCNKPAPKNGGRFCVGRRMKFRSCNTEPCPRDQKDFREEQCSHFDGKHFNINGLPPTIRWVPKYSGILMKDRCKLFCRVAGTMAYYQLRDRVVDGTPCGPDTYDICVQGLCRQAGCDHVLNSKARNDKCGVCGGDNSSCRTVAGTFNNAQYGYNVVV---RIPAGATNIDIKQVSYSGTPEDDNYLALSDSRSNFLLNGNLVVSMFKREISFKGTEIEYSGSNTTVERINCTERIE--DELILQVLCVGSLYN-PDVRYSFNIPIEEQREQFVWD-TSGPWQECSRMCQGERRRKAVCVRKSDHLVVSDQRCELLPRPRGATESCNTDCELRWHVAGK--------SECSSKCGPGYRTVEVLCMRYRQ---TKSVSEKVEVRACG--DLT-KPQSRESCHGDCLQKSWQYSAWSQFVNKCYIYILKSIKSQILMDLKVFLCSCFEMRAGKFYTESLHLCLQCPVTCGHGYQIRAVRCVSGSYGKTVDDQECNAASRPQDSQECELPACPRISSPVSTSRPAAPGQLLTQWRYGSWTTCSVSCGKGERARYVSCRDAQGG--VADESYC------------AHLPRPPETSVC-FSPCGHWREGEWSSCSVSCGVGRSTRQVVC---MNYNQQ---VDESYCHPDE--KP-STEQECAAVPCHSVYTHWPNNQPYFPYDPGSHPGHSSWNVPSADNQWRTGPWGSCSSTCEGGFQRRVVVC-QDSEGRS------TNYCDERVKPSESKSCDSGPCPLWNYGIWGECTQSCGGGQRTRLVVCQRP-NGQRLNEHNCDMLDKPPDVEQCNMQPCPGSASWHRRPWKSCSVTCGKGTRQRELACVYHNQTQTMEENCAHLPRPKTHKPCRVEPCPT----WKTNKWKACPVSCGAGVQTREVYCRLKGKGRIEEERCDAHIRPSSLQSCMLPDCHHYTWSATEWKEC---NASCGKGIRHRTAICVDMKMTPVLDSLCDPSSRPALYEPCFSAPCQYVWVTAAWTECSVSCGVGYQQRMVSCSAVPSTPDLQVFAAHLCLYYHAFSACRLRQCELFSSCRELQIREGIRKDGEHYLSVKSKFIQ-IYCAEMQTNFPKEYVTLRSGQTDNYSEVFGYRLNNPFECPYNGSRR--QDC-ACRNDYPAVGYTLFHRVRLDLSTMRIITTDVQFSQTLLGHSVPFATAGDCYSAARCPQGQFSINLTGTGLKVAESTKWVSHGNYVSVKDGTRIY---------GRCGGFCGKCLP 1774
[Close]
BLAST of A disintegrin and metalloproteinase with thrombospondin motifs vs. Ensembl Cavefish
Match: adamts9 (ADAM metallopeptidase with thrombospondin type 1 motif, 9 [Source:ZFIN;Acc:ZDB-GENE-070814-6])

HSP 1 Score: 366.696 bits (940), Expect = 9.390e-103
Identity = 338/1351 (25.02%), Postives = 533/1351 (39.45%), Query Frame = 1 
Query:  535 PNIIELLIVVTSNFVKRFKKDFRQYILSNVAIATKLLHDPTIKASITXXXXXXXXXXEDYERNNDLHDWSL-LSQDRVVSRFCHWVRQKKQL---WNYSWDSAILINDGVF-----SSNAIGIAHLRSMCND-NNCLAVVDRGFGTGFIIAHELAHQMNARHDFDNAEACSFFEKQYDNKTKYNTIMSTSLFFEYYPFIWSVCSQNVINSFLKSKYSFCLKQRNRHRNLYPHEQINEFFQKYSTGVDYDLNEQCSFAFGEKSEFCETDQNSRK------KCSVLYCRLKRYPICLRADAIIADGTECDVNQHCINGKCLYKNITIAPIDGGWSEYSEWSNCSRPCNGGVQFSYRTCDNPVPADGGRFCTGTKERIRSCNIEECSSFS-DPREESCGKYNLKPY----IPTNDEEFP----------CNLVCITTNHSLKYDI--SLTDGTPCSPFRSDICVKGTCYKTGCDRIVGSKKAIDNCNICAGQNDTCFKKESFFDGSKVAKVRMIRAFRIPPNVYNLFIKKVSQRMTPFTDEVYDDFELLLVVNRRTVIRRSETIEPL-------AGGQLRYSGSKNKVETISIKGKLNVGISIVIKVENTKTTLNLPFISYHYFV-----KDIFVWKYLEVITHPCKDQCGGFIEISPACFKKRDNQRYVDHYCSKATKPEPKIIKCGAICGYRWQRATEHYINSTVNKSCPIRCGTGKVKIPFVCQKINNQDDNNS---------------------------------------LWETVEENLCFAVDLVDRPIEELNC-------VGQCNPLL---WSYGKWEECPIECGTTFRYRNFICKDNKGLEWQKEWCERHLGLPDNKETCLSFNNCRNLTRWVTSPWSRCSNSCESELQKRMVYCFRSEKSDEILDEKFLKIHEQISDAFCDI------HSPKPITERPCSLNSCYFWIXXXXXXXXXXXXLGFRIQSHECKKKFNKNHEMITVDDKFCLKQNLVKPLDVRMRCFLKKCAIESFWIEMEWSKCSVSCGEGLQYRSLKC-GYENENKTLTTWDNNEMCKNKMVPVSIQICKVTPCP----------------------------------KWIYSEWSECEGTCEYGSQHRTVLCTDPISEQILPDSKCDIKNKFPNFQKCLLSKLCGHWIVGKWSQCSASCGLGVKTRTITCNYSNGSKSIDHSVCKSVAPFEEIHCQVKPCSTNAFWWLVKPSECYEYNCQPGIMYAHVRCVNRKFQVLYDSKCSRIKHPSYYVGCLNTTCRRYFWTAESWDNIPCPDISCTMKIRNRDVYCVDDYGNIQKDAMCDQSDKPDTWRLCPSPQNCS 4182
            P  +E+++V  S  V+      + YIL+ ++I + +  DP+I   I I VV +V++      NN+L    +  +    +  FC W + +  L    +   D+AILI            + +G+A L ++C+   +C    D G  T F IAHEL H  N  HD  N       + + D       +M+ +L +   P++WS CS+  I  FL + Y  CL      R  YP         +   G  Y++N+QC   FG  ++ C      R+      + +   CR +  P         ADGT+C   +HC +G C+ K     P++G W  +S + +CSR C GG++ + R C+ P+P +GG++C G + + RSCN E CS  + D REE C  ++ + +    +P N    P          C L C  +  +  Y +   + DGTPC P  +DICV+G C + GCD ++ SK   D C +C G N +C      F+        ++   RIP    N+ +++ S     F+ +  DD  L +  +R   +   + +  +           + YSGS + +E ++   ++     IV++V +     N P + Y Y +        F+W         C   C G  +    C ++ D     D  C  + +P     +C   C  RW  A +          C   CG G   +   C K +  D                                           LW   +          +R  +E  C       V  CN  L   W  G+W EC + CG  +++R   C+  +       +C+     P++ + C      +    W   PW +C+ SC    Q R V C        + D +            C+I      H   P T+          W      +CSA CG G R++   C     ++++    +D  C   +L KP   R  C +  C     W  +EWS+CSVSCG+G   R + C  + ++++ +   D +E C     P + Q C +  CP                                  +W    W  C  TC  G Q R V+C D   E   P + CD ++  PN Q+   S  C  W+ G W +CS  CG G+KTR + C   NG +  D S    V P ++  C  + CS N  W     S C   +C  G  Y +V CV R  + + +  C  +  P     C    C +  W   +W        SC    + R+V+C         D+ C    +P      PS Q CS
Sbjct:  249 PRFVEVMVVADSKMVEHHGSSLQHYILTLMSIVSSIYKDPSIGNLINIVVVKLVII------NNELEGPVISFNAQSTLKNFCIWQQGQNHLDDNHHSHHDTAILITRQDICRARDKCDTLGLAELGTVCDPYRSCSISEDNGLSTAFTIAHELGHVFNMPHDDSN-------KCKEDGVKNQQHVMAPTLNYYTNPWMWSKCSRKYITEFLDTGYGECLLDEPVSRP-YP-------LPQQQPGRIYNVNKQCELIFGPGTQVCPYMTQCRRLWCTSPEGAQRGCRTQHMPW--------ADGTDCAPGKHCKHGLCIPKEHDSTPVEGAWGVWSPFGSCSRTCGGGIKIAVRDCNRPLPRNGGKYCVGRRMKFRSCNSEPCSKQNKDFREEQCATFDGRHFNINGLPPNVRWVPKYSGILMKDRCKLFCRVSGSTAYYQLRDRVIDGTPCGPDTNDICVQGLCRQAGCDHVLNSKARRDKCGVCGGDNSSCKTVAGTFNTVNYGYNVVV---RIPSGATNIDVRQHS-----FSGKPEDDNYLAVANSRGDYLLNGDFVVSMFKREIKVGNAVIEYSGSDHVIERLNCTDRIEE--EIVVQVLSVGNLYN-PDVRYSYNIPIEDKSQQFIWDAYGPWQE-CSRLCQGERKRKILCSRESDRVVVSDQRCHGSPRPAAITEQCNTDCELRWHIARK--------SECTAICGIGYRTLEIYCAKNSRSDSKTQKVDDRYCSNQRKPDDKEVCHGDCSPGGWEYSPWSEVRGHLWGGTQRRSAVCGKSAERNADESKCNSRDKLTVQPCNEFLCPQWKTGEWSECLVTCGKGYKHRQTWCQFGED-RLDDRFCDS--SKPESVQACQQ----QECASWQVGPWGQCTTSCGPGYQLRAVKCVVGSYGAVMDDTECNAATRPTHTQDCEISQCPITHPVSPETKMVPHPGHKTQWRYGSWTQCSATCGKGTRMRYVSC-----RDNQGGVAEDSSCA--HLPKP-PAREVCSVGACGQ---WKALEWSQCSVSCGQGKATRQVLCVNFSDQDQVV---DMSE-CDPDDRPATEQECNMAQCPSRSSDHGGFPPNSDARKRTPSSGRADRIRGGRSHQWRTGPWGACSSTCAGGFQRRVVVCQD---ENGYPANSCD-ESMQPNEQRSCESGPCPQWVYGNWGECSKPCGGGIKTRLVACQRPNGERFNDLSCEIFVKPSDQEQCNTQSCSANPHWSTDPWSSC-SASCGRGYRYRNVTCVGRSGRPIAEENCRHVSRPQKQRRCRGGRCPK--WKTSAWGEC---SASCGAGEQRREVFCQIGDQRRVPDSECSHLPRP------PSTQTCS 1512

HSP 2 Score: 211.46 bits (537), Expect = 2.100e-54
Identity = 199/754 (26.39%), Postives = 304/754 (40.32%), Query Frame = 1 
Query: 2644 LVDRPIEELNCVGQCNPLLWSYGKWEECPIECGTTFRYRNFIC-----------------KDNKGLEWQKEWCE------RHLGLPDNKETCLSFNNCRNLTR--------WVTSPWSRCSNSCESELQKRMVYCFRSEKSDEILDEKFLKIHEQISDAFCDIHSPKPITERPCSLNSCYFWIXXXXXXXXXXXXLGFRIQSHECKKKFNKNHEMITVDDKFCLKQNLVKPLDVRMRCFLKKCAIESFWIEMEWSKCSVSCGEGLQYRSLKCGYENENKTLTTWDNNEMCKNKMVPVSIQICKVTPCPKWIYSEWSECEGTCEYGSQHRTVLCTDPISEQI-LPDSKCDIKNKFPNFQKCLLSKLCGH--WIVGKWSQCSASCGLGVKTRTITCNYSNGSKSIDHSVCKSVAPFEEIHCQVKPCSTNAFWWLVKP-SECYEYNCQPGIMYAHVRCV-------NRKFQVLYDSKCSRIKHPSYYVGCLNTTCRRYFWTAESWDNIPCPDISCTMKIRNRDVYCVDDYGNIQKDAMCDQSDKPDTWRLCPSPQ-NCSNIPR---SCKELKSRQSVSKDGEYSLAIDLNWAYFIYCADMNTEEPKEYLTL---RELNYARTSKYVSTDVSSCIYEEEMEFNQKCPTCKINENLWSITYYNKIRINLSDLSIDVMDDRFSATNGQSFIPFGTAKDCAGSTSCPKGHFKINLRGTGFSVSMETRWNEVYPKYGYRILRKQTSQIVKGWCGGHCSGCSP 4758
            L   P  E+  VG C    W   +W +C + CG     R  +C                  D    E +    +       H G P N +      +     R        W T PW  CS++C    Q+R+V C          DE     +       CD  S +P  +R C    C  W+    G+CS  CG G + +   C++   +       +D  C  +  VKP D + +C  + C+    W    WS CS SCG G +YR++ C   +           E C++   P   + C+   CPKW  S W EC  +C  G Q R V C   I +Q  +PDS+C    + P+ Q C   +      W   +W  CS +CG G + RT+ C   N  +  +        P +   C  +PC    F W+    +EC    C  G     V C        N ++     S C      SY    L +    + W    W   PC  +SC      R V CV   G +  +  C  + +P+  + C +P   C   P+   S   +  +  V  DGE  L++    A  IYC++M+T+ PKEY+TL      N++    +   D + C     +   + C  C+ +     ++ + ++R++LS ++I   D  ++ T+    +PF TA DC  +  CP+G F+INL GTGF V+  T+W          I +      V G CGG+C  C+P
Sbjct: 1185 LPKPPAREVCSVGACG--QWKALEWSQCSVSCGQGKATRQVLCVNFSDQDQVVDMSECDPDDRPATEQECNMAQCPSRSSDHGGFPPNSDARKRTPSSGRADRIRGGRSHQWRTGPWGACSSTCAGGFQRRVVVC---------QDENGYPANS------CD-ESMQPNEQRSCESGPCPQWVYGNWGECSKPCGGGIKTRLVACQRPNGER-----FNDLSC--EIFVKPSD-QEQCNTQSCSANPHWSTDPWSSCSASCGRGYRYRNVTCVGRSGRPIA-----EENCRHVSRPQKQRRCRGGRCPKWKTSAWGECSASCGAGEQRREVFCQ--IGDQRRVPDSECSHLPRPPSTQTCSREECPARYRWSQTEWQTCSKTCGSGGRHRTVVCLDHNEHEVHEMYCSDQGRPGDNEPCNTQPCE---FIWITGDWTEC-SVTCGQGYRRRLVSCSEVHAGVENYEYGHQASSNCPGTPPESYMACNLPSCPSGHTWRVGIWG--PC-SVSCGEGWMERSVQCVSADGELSDE--CPSTSRPEGRKPCSNPSCECVIHPQISLSAVIVSLKTGVVTDGEQVLSVQGK-ALKIYCSEMDTDSPKEYITLTTGEHENFSEVFGFRLMDPTQC--PTNLSRREDC-HCRRDYTAAGLSTFTRVRLDLSKMTIITTDWTYAFTHEGHKVPFATAGDCYSAARCPQGRFRINLSGTGFQVAESTKWISQGNYAVADIHKSVDGSRVTGTCGGYCGKCTP 1892

HSP 3 Score: 98.5969 bits (244), Expect = 5.375e-20
Identity = 101/363 (27.82%), Postives = 147/363 (40.50%), Query Frame = 1 
Query: 2521 CPIRCGTGKVKIPFVCQKINNQDDNNSLWETVEENLCFAVDLVDRPIEELNCVGQ---CNPLLWSYGKWEECPIECGTTFRYRNFICKDNKGLEWQKEWCERHLGLPDNKETCLSFNNCRNLTRWVTSPWSRCSNSCESELQKRMVYCFRSEKSDEILDEKFLKIHEQISDAFCDIHSPKPITERPCSLNSC---YFWIXXXXXXXXXXXXLGFRIQSHECKKKFNKNHEMITVDDKFCLKQNLVKPLDVRMRCFLKKCAIESFWIEMEWSKCSVSCGEGLQYRSLKC-----GYENENKTLTTWDNNEMCKNKMVPVSIQICKVTPCPK---WIYSEWSECEGTCEYGSQHRTVLCTDPISE 3567
            C   CG G       CQ+ N +  N+            + ++  +P ++  C  Q    NP  WS   W  C   CG  +RYRN  C    G    +E C RH+  P  +  C          +W TS W  CS SC +  Q+R V+C       +I D++      ++ D+ C  H P+P + + CS   C   Y W +++   CS  CG G R ++  C      +H    V + +C  Q   +P D    C  + C  E  WI  +W++CSV+CG+G + R + C     G EN         N   C     P S   C +  CP    W    W  C  +C  G   R+V C     E
Sbjct: 1356 CSKPCGGGIKTRLVACQRPNGERFND-----------LSCEIFVKPSDQEQCNTQSCSANPH-WSTDPWSSCSASCGRGYRYRNVTCVGRSGRPIAEENC-RHVSRPQKQRRCRGG----RCPKWKTSAWGECSASCGAGEQRREVFC-------QIGDQR------RVPDSECS-HLPRPPSTQTCSREECPARYRWSQTEWQTCSKTCGSGGRHRTVVC-----LDHNEHEVHEMYCSDQG--RPGD-NEPCNTQPC--EFIWITGDWTECSVTCGQGYRRRLVSCSEVHAGVENYEYGHQASSN---CPG-TPPESYMACNLPSCPSGHTWRVGIWGPCSVSCGEGWMERSVQCVSADGE 1673
[Close]
BLAST of A disintegrin and metalloproteinase with thrombospondin motifs vs. Ensembl Cavefish
Match: adamts9 (ADAM metallopeptidase with thrombospondin type 1 motif, 9 [Source:ZFIN;Acc:ZDB-GENE-070814-6])

HSP 1 Score: 344.354 bits (882), Expect = 3.731e-96
Identity = 312/1226 (25.45%), Postives = 496/1226 (40.46%), Query Frame = 1 
Query:  535 PNIIELLIVVTSNFVKRFKKDFRQYILSNVAIATKLLHDPTIKASITXXXXXXXXXXEDYERNNDLHDWSL-LSQDRVVSRFCHWVRQKKQL---WNYSWDSAILINDGVF-----SSNAIGIAHLRSMCND-NNCLAVVDRGFGTGFIIAHELAHQMNARHDFDNAEACSFFEKQYDNKTKYNTIMSTSLFFEYYPFIWSVCSQNVINSFLKSKYSFCLKQRNRHRNLYPHEQINEFFQKYSTGVDYDLNEQCSFAFGEKSEFCETDQNSRKKCSVLYCRLKRYPI--CLRADAIIADGTECDVNQHCINGKCLYKNITIAPIDGGWSEYSEWSNCSRPCNGGVQFSYRTCDNPVPADGGRFCTGTKERIRSCNIEECSSFS-DPREESCGKYNLKPY----IPTNDEEFP----------CNLVCITTNHSLKYDI--SLTDGTPCSPFRSDICVKGTCYKTGCDRIVGSKKAIDNCNICAGQNDTCFKKESFFDGSKVAKVRMIRAFRIPPNVYNLFIKKVSQRMTPFTDEVYDDFELLLVVNRRTVIRRSETIEPL-------AGGQLRYSGSKNKVETISIKGKLNVGISIVIKVENTKTTLNLPFISYHYFV-----KDIFVWKYLEVITHPCKDQCGGFIEISPACFKKRDNQRYVDHYCSKATKPEPKIIKCGAICGYRWQRATEHYINSTVNKSCPIRCGTGKVKIPFVC----------QKINNQ--------DDN-----------------NSLWETVEENLCFAVDLVDRPIEELNC-------VGQCNPLL---WSYGKWEECPIECGTTFRYRNFICKDNKGLEWQKEWCERHLGLPDNKETCLSFNNCRNLTRWVTSPWSRCSNSCESELQKRMVYCFRSEKSDEILDEKFLKIHEQISDAFCDI------HSPKPITERPCSLNSCYFWIXXXXXXXXXXXXLGFRIQSHECKKKFNKNHEMITVDDKFCLKQNLVKPLDVRMRCFLKKCAIESFWIEMEWSKCSVSCGEGLQYRSLKC-GYENENKTLTTWDNNEMCKNKMVPVSIQICKVTPCP----------------------------------KWIYSEWSECEGTCEYGSQHRTVLCTDPISEQILPDSKCDIKNKFPNFQKCLLSKLCGHWIVGKWSQCSASCGLGVKTRTITCNYSNGSKSIDHSVCKSVAPFEEIHCQVKPCSTNAFW 3831
            P  +E+++V  S  V+      + YIL+ ++I + +  DP+I   I I VV +V++      NN+L    +  +    +  FC W + +  L    +   D+AILI            + +G+A L ++C+   +C    D G  T F IAHEL H  N  HD  N       + + D       +M+ +L +   P++WS CS+  I  FL + Y  CL      R  YP         +   G  Y++N+QC   FG  ++ C        +C  L+C         C       ADGT+C   +HC +G C+ K     P++G W  +S + +CSR C GG++ + R C+ P+P +GG++C G + + RSCN E CS  + D REE C  ++ + +    +P N    P          C L C  +  +  Y +   + DGTPC P  +DICV+G C + GCD ++ SK   D C +C G N +C      F+        ++   RIP    N+ +++ S     F+ +  DD  L +  +R   +   + +  +           + YSGS + +E ++   ++     IV++V +     N P + Y Y +        F+W         C   C G  +    C ++ D     D  C  + +P     +C   C  RW  A +          C   CG G   +   C          QK++++        DD                  + LW   +          +R  +E  C       V  CN  L   W  G+W EC + CG  +++R   C+  +       +C+     P++ + C      +    W   PW +C+ SC    Q R V C        + D +            C+I      H   P T+          W      +CSA CG G R++   C     ++++    +D  C   +L KP   R  C +  C     W  +EWS+CSVSCG+G   R + C  + ++++ +   D +E C     P + Q C +  CP                                  +W    W  C  TC  G Q R V+C D   E   P + CD ++  PN Q+   S  C  W+ G W +CS  CG G+KTR + C   NG +  D S    V P ++  C  + CS N  W
Sbjct:  342 PRFVEVMVVADSKMVEHHGSSLQHYILTLMSIVSSIYKDPSIGNLINIVVVKLVII------NNELEGPVISFNAQSTLKNFCIWQQGQNHLDDNHHSHHDTAILITRQDICRARDKCDTLGLAELGTVCDPYRSCSISEDNGLSTAFTIAHELGHVFNMPHDDSN-------KCKEDGVKNQQHVMAPTLNYYTNPWMWSKCSRKYITEFLDTGYGECLLDEPVSRP-YP-------LPQQQPGRIYNVNKQCELIFGPGTQVCPY----MTQCRRLWCTSPEGAQRGCRTQHMPWADGTDCAPGKHCKHGLCIPKEHDSTPVEGAWGVWSPFGSCSRTCGGGIKIAVRDCNRPLPRNGGKYCVGRRMKFRSCNSEPCSKQNKDFREEQCATFDGRHFNINGLPPNVRWVPKYSGILMKDRCKLFCRVSGSTAYYQLRDRVIDGTPCGPDTNDICVQGLCRQAGCDHVLNSKARRDKCGVCGGDNSSCKTVAGTFNTVNYGYNVVV---RIPSGATNIDVRQHS-----FSGKPEDDNYLAVANSRGDYLLNGDFVVSMFKREIKVGNAVIEYSGSDHVIERLNCTDRIEE--EIVVQVLSVGNLYN-PDVRYSYNIPIEDKSQQFIWDAYGPWQE-CSRLCQGERKRKILCSRESDRVVVSDQRCHGSPRPAAITEQCNTDCELRWHIARK--------SECTAICGIGYRTLEIYCAKNSRSDSKTQKVDDRYCSNQRKPDDKEVCHGDCSPGGWEYSPWSELWGGTQRRSAVCGKSAERNADESKCNSRDKLTVQPCNEFLCPQWKTGEWSECLVTCGKGYKHRQTWCQFGED-RLDDRFCDS--SKPESVQACQQ----QECASWQVGPWGQCTTSCGPGYQLRAVKCVVGSYGAVMDDTECNAATRPTHTQDCEISQCPITHPVSPETKMVPHPGHKTQWRYGSWTQCSATCGKGTRMRYVSC-----RDNQGGVAEDSSCA--HLPKP-PAREVCSVGACGQ---WKALEWSQCSVSCGQGKATRQVLCVNFSDQDQVV---DMSE-CDPDDRPATEQECNMAQCPSRSSDHGGFPPNSDARKRTPSSGRADRIRGGRSHQWRTGPWGACSSTCAGGFQRRVVVCQD---ENGYPANSCD-ESMQPNEQRSCESGPCPQWVYGNWGECSKPCGGGIKTRLVACQRPNGERFNDLSCEIFVKPSDQEQCNTQSCSANPHW 1496

HSP 2 Score: 114.775 bits (286), Expect = 5.611e-25
Identity = 124/444 (27.93%), Postives = 180/444 (40.54%), Query Frame = 1 
Query: 2893 SPWSRCSNSCESELQKRMVYCFRSEKSDEILDEKFLKIHEQISDAFCDIHSPKP--ITERPCSLNSCYFWIXXXXXXXXXXXXLGFRIQSHECKKKFNKNHEMITVDDKFCLKQNLVKPLDVRMRCFLKKCAIESFWIEMEWSKCSVSCGEGLQYRSLKCGYENENKTLTTWDNNEMCKNKMVPVSIQICKVTPCPKWIYSEWSECEGTCEYGSQHRTVLCTDPISEQILPDSKCDIKNKFPNFQKCLLSKLCGHWIVGKWSQCSASCGLGVKTRTITCNYSNGSKSIDHSVCKSVA-PFEEIHCQVKPC----------------STNAFWWLVKPSECYEYNCQPGIMYAHVRCVNRKFQVLYDSKCSRIKHPSYYVGCLNTTCRRYFWTAESWDNIPCPDISCTMKIRNRDVYCVD--DYGNIQKDAMCDQSDKPDTWRLC 4161
             PW  CS  C+ E +KR + C R  +SD ++          +SD  C   SP+P  ITE+ C+ +    W  ++  +C+A CG+G+R     C K    + +   VDD++C  Q   KP D  + C    C+    W    WS+       G Q RS  CG   E         +E   N    +++Q C    CP+W   EWSEC  TC  G +HR   C     E  L D  CD  +K  + Q C   + C  W VG W QC+ SCG G + R + C   +    +D + C +   P     C++  C                     W     ++C    C  G    +V C + +  V  DS C+ +  P     C    C +  W A  W       +SC      R V CV+  D   +   + CD  D+P T + C
Sbjct:  938 GPWQECSRLCQGE-RKRKILCSR--ESDRVV----------VSDQRCH-GSPRPAAITEQ-CNTDCELRWHIARKSECTAICGIGYRTLEIYCAKNSRSDSKTQKVDDRYCSNQR--KPDDKEV-CH-GDCS-PGGWEYSPWSEL----WGGTQRRSAVCGKSAERNA------DESKCNSRDKLTVQPCNEFLCPQWKTGEWSECLVTCGKGYKHRQTWCQ--FGEDRLDDRFCD-SSKPESVQACQQQE-CASWQVGPWGQCTTSCGPGYQLRAVKCVVGSYGAVMDDTECNAATRPTHTQDCEISQCPITHPVSPETKMVPHPGHKTQWRYGSWTQC-SATCGKGTRMRYVSCRDNQGGVAEDSSCAHLPKPPAREVCSVGACGQ--WKALEWSQC---SVSCGQGKATRQVLCVNFSDQDQVVDMSECDPDDRPATEQEC 1341

HSP 3 Score: 96.2857 bits (238), Expect = 2.652e-19
Identity = 84/326 (25.77%), Postives = 116/326 (35.58%), Query Frame = 1 
Query: 2701 WSYGKWEECPIECGTTFRYRNFICKDNKGLEWQKEWCERHLGLPDNKETCLSFNNCRNLTRWVTSPWSRCSNSCESELQKRMVYCFRSEKSDEILDEKFLKIHEQISDAFCDIHSPKPITERPCSLNSCYFWIXXXXXXXXXXXXLGFRIQSHECKKKFNKNHEMITVDDKFCLKQNLVKPLDVRMRCFLKKCAIESFWIEMEWSKCSVSCGEGLQYRSLKCGYENENKTLTTWDNNEMCKNKMVPVSIQICKVTPCPKWIYSEWSECEGTCEYGSQHRTVLCTDPISEQILPDSKCDIKNKFPNFQKCLLSKLCG--HWIVGKWS 3672
            W YG W +C   CG   R R   C+DN+G   +   C  HL  P  +E C S   C    +W    WS+CS SC      R V C      D+++D            + CD    +P TE+ C++  C            +    GF   S   K+  +                          R    +      W    W  CS +C  G Q R + C  EN     +       C   M P   + C+  PCP+W+Y  W EC   C  G + R V C  P  E+   D  C+I  K  + ++C         HW    WS
Sbjct: 1235 WRYGSWTQCSATCGKGTRMRYVSCRDNQGGVAEDSSCA-HLPKPPAREVC-SVGAC---GQWKALEWSQCSVSCGQGKATRQVLCVNFSDQDQVVDM-----------SECDPDD-RPATEQECNMAQC---------PSRSSDHGGFPPNSDARKRTPSSG------------------------RADRIRGGRSHQWRTGPWGACSSTCAGGFQRRVVVCQDENGYPANS-------CDESMQPNEQRSCESGPCPQWVYGNWGECSKPCGGGIKTRLVACQRPNGER-FNDLSCEIFVKPSDQEQCNTQSCSANPHWSTDPWS 1502

HSP 4 Score: 92.0485 bits (227), Expect = 4.157e-18
Identity = 86/348 (24.71%), Postives = 131/348 (37.64%), Query Frame = 1 
Query: 3295 WIEMEWSKCSVSCGEGLQYRSLKCGYENENKTLTTWDNNEMCKNKMVPVSIQICKVTPCPKWIYSEWSECEGTCEYGSQHRTVLCTDPISEQILPDSKCDIKNKFPNFQKCLLS------------KLCGH------WIVGKWSQCSASCGLGVKTRTITCNYSNGSKSIDHSVCKSVAPFEEIHCQVKPCSTNAFWWLVKPSECYEYNCQPGIMYAHVRCVN--RKFQVLYDSKCSRIKHPSYYVGCLNTTC--------------------------------RRYFWTAESWDNIPCPDISCTMKIRNRDVYCVDDYGNIQKDAMCDQSDKPDTWRLC---PSPQ 4173
            W   EWS+C V+CG+G ++R   C +  +        ++  C +   P S+Q C+   C  W    W +C  +C  G Q R V C       ++ D++C+   +  + Q C +S            K+  H      W  G W+QCSA+CG G + R ++C  + G  + D S      P     C V  C     W  ++ S+C   +C  G     V CVN   + QV+  S+C     P+    C    C                                R + W    W        +C    + R V C D+ G       CD+S +P+  R C   P PQ
Sbjct: 1105 WKTGEWSECLVTCGKGYKHRQTWCQFGEDRL------DDRFCDSSK-PESVQACQQQECASWQVGPWGQCTTSCGPGYQLRAVKCVVGSYGAVMDDTECNAATRPTHTQDCEISQCPITHPVSPETKMVPHPGHKTQWRYGSWTQCSATCGKGTRMRYVSCRDNQGGVAEDSSCAHLPKPPAREVCSVGACGQ---WKALEWSQC-SVSCGQGKATRQVLCVNFSDQDQVVDMSECDPDDRPATEQECNMAQCPSRSSDHGGFPPNSDARKRTPSSGRADRIRGGRSHQWRTGPWGAC---SSTCAGGFQRRVVVCQDENGYPANS--CDESMQPNEQRSCESGPCPQ 1436
[Close]
BLAST of A disintegrin and metalloproteinase with thrombospondin motifs vs. Ensembl Cavefish
Match: ADAMTS20 (ADAM metallopeptidase with thrombospondin type 1 motif 20 [Source:HGNC Symbol;Acc:HGNC:17178])

HSP 1 Score: 345.125 bits (884), Expect = 5.643e-96
Identity = 330/1288 (25.62%), Postives = 510/1288 (39.60%), Query Frame = 1 
Query:  535 PNIIELLIVVTSNFVKRFKKDFRQYILSNVAIATKLLHDPTIKASITXXXXXXXXXXEDYERNN-DLHDWSLLSQDRVVSRFCHWVRQKKQLWNYS---WDSAILIND-----GVFSSNAIGIAHLRSMCND-NNCLAVVDRGFGTGFIIAHELAHQMNARHDFDNAEACSFFEKQYDNKTKYNTIMSTSLFFEYYPFIWSVCSQNVINSFLKSKYSFCLKQRNRHRNLYPHEQINEFFQKYSTGVDYDLNEQCSFAFGEKSEFCETDQNSRKKCSVLYCRLKR--YPICLRADAIIADGTECDVNQHCINGKCLYKNITIAPIDGGWSEYSEWSNCSRPCNGGVQFSYRTCDNPVPADGGRFCTGTKERIRSCNIEECS-SFSDPREESCGKYNLKPY----IPTNDEEFP----------CNLVCITTNHSLKYDI--SLTDGTPCSPFRSDICVKGTCYKTGCDRIVGSKKAIDNCNICAGQNDTCFKKESFFDGSKVAKVRMIRAFRIPPNVYNLFIKKVSQRMTPFTDE--VYDDFELLLVVNRRTVIRRSETIEPLAGGQLRYSGSKNKVETISIKGKLNVGISIVIKVENTKTTLNLPFISYHYFV-----KDIFVWKYLEVITHPCKDQCGGFIEISPACFKKRDNQRYVDHYCSKATKPEPKIIKCGAICGYRWQRATEHYINSTVNKSCPIRCGTGKVKIPFVCQKINNQDDNNSLWETVEENLCFAVDLVDRPIEELNCVGQCNPLLWSYGKWEECPIECGTTFRYRNFICKDNKGLEWQKEWCERHLGLPDNKETCLSFNNCRNLTRWVTSPWSRCSNSCESELQKRMVYCFRSEKSDEILDEKFLKIHEQISDAFCDIHS-PK---PI-TERPCSLNSCYF-WIXXXXXXXXXXXXLGFRIQSHECKKKFNKNHEMITVDDKFCLKQNLVKPLDVRMRCFLKKCAIESFWIEMEWSKCSVSCGEGLQYRSLKCGYENENKTLTTWDNNEMCKNKMVPVSIQICKVTPCP---------------------------------KWIYSEWSECEGTCEYGSQHRTVLCTDPISEQILPDSKCDIKNKFPNFQKCLLSKLCGHWIVGKWSQCSASCGLGVKTRTITCNYSNGSKSIDHSVCKSVAPFEEIHCQVKPCSTNAFWWLVKPSECYEYNCQPGIMYAHVRCVNRKFQVLYDSKCSRIKHPSYYVGCLNTTCRRYFWTAESWDNIPCPDISCTMKIRNRDVYC-VDDYGNIQKDAMCDQSDKPDTWRLCPSP 4170
            P  +EL++   +  V+   ++   YIL+ +++   +  DP++   I I +V ++++  + E  N + +  + L        FC W +    L +      D+A+LI            + +G+A L +MC+   +C    + G  + F IAHEL H  N  HD DN +      ++   K +Y+ +M+ +L ++  P+ WS CS+  I  FL + Y  CL          P  +  +   K   G  Y++N QC   FG  S+ C       K+C  L+C      +  C      +ADGT+C    +C +G C+ K I   P+ G W  +  +S CSR C GG + + R C+ P P +GGRFC G + + RSCN E C     D REE C  ++ K +    +P      P          C L C        Y +   + DGTPC P   DICV+G C + GCD ++ SK   D C +C G N +C      F+ ++     ++   RIP    N+ IK+VS   TP  D      D     ++N   V+   +      G ++ YSGS   VE I+   ++     ++++V    +  N P + Y + +     ++ FVW         C   C G       C +K D+    D  C    +P      C   C  RW  A +          C  +CG G   +  +C +        S+ E VE   C   DL  +P    +C G C    W Y  W +                    G EW     E  +G      TCLS          +  PW  C +      Q R V C        + D++            C++ + P+   P+ T RP +       W       CS  CG G R +   C     ++ +    D+ +C   +L +P +  + CF   C     W E EWS CSVSCG G   R + C   N+        +   C     P + Q C   PC                                  +W    W  C  TCE G Q R V+C D         + CD + K P+  K   S  C  W  G W +C+ SCG G +TR + C   NG +  +H+      P +   C ++PC  +A W   +P +     C  G     + CV        +  C+ +  P  +  C    C    W    W   P   +SC   ++ R+VYC +   G I+++  CD   +P + + C  P
Sbjct:  244 PRFVELMVTADAKMVRHHGRNLEHYILTIMSVVAAVYKDPSVGNLINIMIVKLIVIHNEQEGPNVNFYAATTLHN------FCVWQQSHNVLDDSHPSHHDTALLITREDICRAKDKCDTLGLAELGTMCDPYRSCSISEENGLSSAFTIAHELGHVFNMPHD-DNPKC-----REAGIKHQYH-VMAPTLNYDTSPWSWSKCSRKYITEFLDTGYGECLLDE-------PVGKTYDLPVKLP-GQLYNVNRQCELMFGPGSQVCPF----MKQCKRLWCTSAEGDHKGCRTQHMPLADGTDCGHGMYCKHGMCVNKEIESRPVHGEWGPWGPYSVCSRTCGGGTRSTSRDCNKPAPKNGGRFCVGRRMKFRSCNTEPCPRDQKDFREEQCSHFDGKHFNINGLPPTIRWVPKYSGILMKDRCKLFCRVAGTMAYYQLRDRVVDGTPCGPDTYDICVQGLCRQAGCDHVLNSKARNDKCGVCGGDNSSCRTVAGTFNNAQYGYNVVV---RIPAGATNIDIKQVSYSGTPEDDNYLALSDSRSNFLLNGNLVVSMFKREISFKGTEIEYSGSNTTVERINCTERIE--DELILQVLCVGSLYN-PDVRYSFNIPIEEQREQFVWD-TSGPWQECSRMCQGERRRKAVCVRKSDHLVVSDQRCELLPRPRGATESCNTDCELRWHVAGK--------SECSSKCGPGYRTVEVLCMRYRQ---TKSVSEKVEVRACG--DLT-KPQSRESCHGDCLQKSWQYSAWSQ-------------------GGGEWLSSLGE--VGWYYLGSTCLST---------LVLPWVTCGHG----YQIRAVRCVSGSYGKTVDDQECNAASRPQDSQECELPACPRISSPVSTSRPAAPGQLLTQWRYGSWTTCSVSCGKGERARYVSC-----RDAQGGVADESYCA--HLPRPPETSV-CF-SPCG---HWREGEWSSCSVSCGVGRSTRQVVCMNYNQQV------DESYCHPDEKPSTEQECAAVPCHSVYTHWPNNQPYFPYDPGSHPGHSSWNVPSADNQWRTGPWGSCSSTCEGGFQRRVVVCQDSEGRST---NYCDERVK-PSESKSCDSGPCPLWNYGIWGECTQSCGGGQRTRLVVCQRPNGQRLNEHNCDMLDKPPDVEQCNMQPCPGSASWHR-RPWKSCSVTCGKGTRQRELACVYHNQTQTMEENCAHLPRPKTHKPCRVEPCPT--WKTNKWKACP---VSCGAGVQTREVYCRLKGKGRIEEE-RCDAHIRPSSLQSCMLP 1422

HSP 2 Score: 196.052 bits (497), Expect = 8.710e-50
Identity = 201/783 (25.67%), Postives = 305/783 (38.95%), Query Frame = 1 
Query: 2518 SCPIRCGTGKVKIPFVCQKINNQDDNNSLWETVEENLCFAVDLVDRPIEELNCVGQCNPLLWSYGKWEECPIECGTTFRYRNFICKDNKGLEWQKEWCERHLGLPDNKETCL-----------------------------SFNNCRNLTRWVTSPWSRCSNSCESELQKRMVYCFRSE-KSDEILDEKFLKIHEQISDAFCDIHSPKPITERPCSLNSCYFWIXXXXXXXXXXXXLGFRIQSHECKKKFNKNHEMITVDDKFCLKQNLVKPLDVRMRCFLKKCAIESFWIEMEWSKCSVSCGEGLQYRSLKCGYENENKTLTTWDNNEMCKNKMVPVSIQICKVTPCPKWIYSEWSECEGTCEYGSQHRTVLCTDPISEQILPDSKCDIKNKFPNFQKCLLSKLCGH--WIVGKWSQCSASCGLGVKTRTITCNYSNGSKSIDHSVCKSVAPFEEIHCQVKPCSTNAFWWLVKPSECYEYNCQPGIMYAHVRCVNRKFQVLYDSKCSRIKHPSYYVGCLNTTCRRY-FWTAESWDNIPCPDISCTMKIRNRDVYCVDDYGNIQKDAMCDQSDKPDTWRLCPSPQNCSNIPRSCKELKSRQSVSKDGEYSLAIDLNWAYFIYCADMNTEEPKEYLTLREL---NYARTSKYVSTDVSSCIYEEEMEFNQKCPTCKINENLWSITYYNKIRINLSDLSIDVMDDRFSATNGQSFIPFGTAKDCAGSTSCPKGHFKINLRGTGFSVSMETRWNEVYPKYGYRILRKQTSQIVKGWCGGHCSGCSP 4758
            +C + CG G+      C+               +E+ C  +    RP E   C   C    W  G+W  C + CG     R  +C  N   +  + +C      P  ++ C                              S+N      +W T PW  CS++CE   Q+R+V C  SE +S    DE+                  KP   + C    C  W     G+C+  CG G R +   C++   +      +++  C    L KP DV  +C ++ C   + W    W  CSV+CG+G + R L C Y N+ +T+      E C +   P + + C+V PCP W  ++W  C  +C  G Q R V C      +I  + +CD   +  + Q C+L   C H  W   +W + S    L   TR I          +   V K +  F+   C V  C       +V    C      P +     +                   P     C    C  + +W    W        +C   +  R V C++      K  +C  S KP +   C   Q    +  SC+EL+ R+ + KDGE+ L++   +   IYCA+M T  PKEY+TLR     NY+    Y   +   C Y       Q C  C+ +      T ++++R++LS + I   D +FS T     +PF TA DC  +  CP+G F INL GTG  V+  T+W         ++ R +    + G CGG C  C P
Sbjct: 1066 TCSVSCGKGERARYVSCRDAQGG--------VADESYCAHLP---RPPETSVCFSPCG--HWREGEWSSCSVSCGVGRSTRQVVCM-NYNQQVDESYCHPDE-KPSTEQECAAVPCHSVYTHWPNNQPYFPYDPGSHPGHSSWNVPSADNQWRTGPWGSCSSTCEGGFQRRVVVCQDSEGRSTNYCDERV-----------------KPSESKSCDSGPCPLWNYGIWGECTQSCGGGQRTRLVVCQRPNGQR-----LNEHNC--DMLDKPPDVE-QCNMQPCPGSASWHRRPWKSCSVTCGKGTRQRELACVYHNQTQTM-----EENCAHLPRPKTHKPCRVEPCPTWKTNKWKACPVSCGAGVQTREVYCRLKGKGRI-EEERCDAHIRPSSLQSCMLPD-CHHYTWSATEWKEVSTPLAL---TRAIL---------VKIVVMKCLFGFQ---CSVS-CGVGYQQRMVS---CSAVPSTPDLQVFAAQSYTHASPSECPEPPPSHTKP-----CQMPECPPHGYWKVGPWSKC---SQTCGAGMMERMVECLNAKHLPSK--ICPLSSKPTSQAACRLRQ--CELFSSCRELQIREGIRKDGEHYLSVKSKFIQ-IYCAEMQTNFPKEYVTLRSGQTDNYSEVFGYRLNNPFECPYNGSRR--QDC-ACRNDYPAVGYTLFHRVRLDLSTMRIITTDVQFSQTLLGHSVPFATAGDCYSAARCPQGQFSINLTGTGLKVAESTKWVSHGNYVSVKVHRSEDGTRIYGRCGGFCGKCLP 1766

HSP 3 Score: 92.0485 bits (227), Expect = 4.298e-18
Identity = 134/505 (26.53%), Postives = 194/505 (38.42%), Query Frame = 1 
Query: 2884 WVTS-PWSRCSNSCESELQKRMVYCFRSEKSDEILDEKFLKIHEQISDAFCD-IHSPKPITERPCSLNSCYFWIXXXXXXXXXXXXLGFRIQSHECKKKFNKNHEMITVDDKFCLKQNLVKPLDVRMRCF---LKKCAIESFWIE--MEW-------------SKCS-------VSCGEGLQYRSLKCGYENENKTLTTWDNNEMCKNKMVPVSIQICKVTPCPK-------------------WIYSEWSECEGTCEYGSQHRTVLCTDPISEQILPDSKCDIKNKFPNFQKCLLSKLCGHWIVGKWSQCSASCGLGVKTRTITCNYSNGSKSIDHSVCK-SVAPFEEIHCQVKPC-STNAFWWLVKPSECYEYNCQPGIMYAHVRCVNRKFQVLYDSKCSRIKHPSY---YVGCLNTTCRRYFWTAE--------SWDNIPCP----------DISCTMKIRNRDVYCVDDYGNIQKDAMCDQSDKPDTWRLC---PSPQNCS 4182
            W TS PW  CS  C+ E +++ V C R  KSD ++          +SD  C+ +  P+  TE  C+ +    W  +   +CS+KCG G+R     C +          V+ + C   +L KP   R  C    L+K    S W +   EW             S C        V+CG G Q R+++C   +  KT+    +++ C     P   Q C++  CP+                   W Y  W+ C  +C  G + R V C D     +  +S C    + P    C     CGHW  G+WS CS SCG+G  TR + C   N ++ +D S C     P  E  C   PC S    W   +P   Y+    PG    +V   + +++      CS      +    V C ++  R   +  E        S D+ PCP            SC    R R V C    G    +  CD  DKP     C   P P + S
Sbjct:  836 WDTSGPWQECSRMCQGERRRKAV-CVR--KSDHLV----------VSDQRCELLPRPRGATES-CNTDCELRWHVAGKSECSSKCGPGYRTVEVLCMRYRQTKSVSEKVEVRAC--GDLTKP-QSRESCHGDCLQKSWQYSAWSQGGGEWLSSLGEVGWYYLGSTCLSTLVLPWVTCGHGYQIRAVRCVSGSYGKTV----DDQECNAASRPQDSQECELPACPRISSPVSTSRPAAPGQLLTQWRYGSWTTCSVSCGKGERARYVSCRD-AQGGVADESYCAHLPRPPETSVCF--SPCGHWREGEWSSCSVSCGVGRSTRQVVC--MNYNQQVDESYCHPDEKPSTEQECAAVPCHSVYTHWPNNQPYFPYDPGSHPGHSSWNVPSADNQWRTGPWGSCSSTCEGGFQRRVVVCQDSEGRSTNYCDERVKPSESKSCDSGPCPLWNYGIWGECTQSCGGGQRTRLVVCQRPNGQRLNEHNCDMLDKPPDVEQCNMQPCPGSAS 1314

HSP 4 Score: 53.5286 bits (127), Expect = 2.406e-6
Identity = 60/249 (24.10%), Postives = 90/249 (36.14%), Query Frame = 1 
Query: 2293 VWKYLEVITHPCKDQCGGFIEISPACFKKRDNQRYVDHYCSKATKPEPKIIKCGA---ICGYRWQRATEHYINSTVNKSCPIRCGTGKVKIPFVCQKINNQDDNNSLWETVEENLCFAVDLVDRPIEELNCVGQCNPLLWSYGKWEECPIECGTTFRYRNFICKDNKGLEWQKEWCERHLGLPDNKETCLSFNNCRNLTRWVTSPWS-------------------------RCSNSCESELQKRMVYC 2955
            +W Y   I   C   CGG         ++ + QR  +H C    KP P + +C          W R           KSC + CG G  +    C   N         +T+EEN       + RP     C  +  P  W   KW+ CP+ CG   + R   C+       ++E C+ H+  P + ++C+   +C + T W  + W                          +CS SC    Q+RMV C
Sbjct: 1255 LWNY--GIWGECTQSCGGGQRTRLVVCQRPNGQRLNEHNCDMLDKP-PDVEQCNMQPCPGSASWHRRPW--------KSCSVTCGKGTRQRELACVYHNQT-------QTMEENCAH----LPRPKTHKPCRVEPCPT-WKTNKWKACPVSCGAGVQTREVYCRLKGKGRIEEERCDAHI-RPSSLQSCM-LPDCHHYT-WSATEWKEVSTPLALTRAILVKIVVMKCLFGFQCSVSCGVGYQQRMVSC 1477
[Close]
BLAST of A disintegrin and metalloproteinase with thrombospondin motifs vs. Ensembl Cavefish
Match: ADAMTS20 (ADAM metallopeptidase with thrombospondin type 1 motif 20 [Source:HGNC Symbol;Acc:HGNC:17178])

HSP 1 Score: 343.969 bits (881), Expect = 1.359e-95
Identity = 319/1298 (24.58%), Postives = 506/1298 (38.98%), Query Frame = 1 
Query:  535 PNIIELLIVVTSNFVKRFKKDFRQYILSNVAIATKLLHDPTIKASITXXXXXXXXXXEDYERNN-DLHDWSLLSQDRVVSRFCHWVRQKKQLWNYS---WDSAILIND-----GVFSSNAIGIAHLRSMCND-NNCLAVVDRGFGTGFIIAHELAHQMNARHDFDNAEACSFFEKQYDNKTKYNTIMSTSLFFEYYPFIWSVCSQNVINSFLKSKYSFCLKQRNRHRNLYPHEQINEFFQKYSTGVDYDLNEQCSFAFGEKSEFCETDQNSRKKCSVLYCRLKR--YPICLRADAIIADGTECDVNQHCINGKCLYKNITIAPIDGGWSEYSEWSNCSRPCNGGVQFSYRTCDNPVPADGGRFCTGTKERIRSCNIEECS-SFSDPREESCGKYNLKPY----IPTNDEEFP----------CNLVCITTNHSLKYDI--SLTDGTPCSPFRSDICVKGTCYKTGCDRIVGSKKAIDNCNICAGQNDTCFKKESFFDGSKVAKVRMIRAFRIPPNVYNLFIKKVSQRMTPFTDE--VYDDFELLLVVNRRTVIRRSETIEPLAGGQLRYSGSKNKVETISIKGKLNVGISIVIKVENTKTTLNLPFISYHYFV-----KDIFVWKYLEVITHPCKDQCGGFIEISPACFKKRDNQRYVDHYCSKATKPEPKIIKCGAICGYRWQRATEHYINSTVNKSCPIRCGTGKVKIPFVCQKINNQDDNNSLWETVEENLCFAVDLVDRPIEELNCVGQCNPLLWSYGKWE----------------------------------------------ECPIECGTTFRYRNFICKDNK-GLEWQKEWCERHLGLPDNKE--------------TCLSFNNCRNLTRWVTSPWSRCSNSCESELQKRMVYCFRSEKSDEILDEKFLKIHEQISDAFCDIHSPKPITERPCSLNSCYFWIXXXXXXXXXXXXLGFRIQSHECKKKFNKNHEMITVDDKFCLKQNLVKPLDVRMRCFLKKC------------------------------AIESFWIEMEWSKCSVSCGEGLQYRSLKCGYENENKTLTTWDNNEMCKNKMVPVSIQICKVTPCPKWIYSEWSECEGTCEYGSQHRTVLCTDPISEQILPDSKCDIKNKFPNFQKCLLSKLCG--HWIVGKWSQCSASCGLGVKTRTITCNYSNGSKSIDHSVCKSVAPFEEIHCQVKPCSTNAFWWLVKPSECYEYNCQPGIMYAHVRCVNRKFQVLYDSKCSRIKHPSYYVGCLNTTCRRYFWTAESWDNIPCP 4041
            P  +EL++   +  V+   ++   YIL+ +++   +  DP++   I I +V ++++  + E  N + +  + L        FC W +    L +      D+A+LI            + +G+A L +MC+   +C    + G  + F IAHEL H  N  HD DN +      ++   K +Y+ +M+ +L ++  P+ WS CS+  I  FL + Y  CL          P  +  +   K   G  Y++N QC   FG  S+ C       K+C  L+C      +  C      +ADGT+C    +C +G C+ K I   P+ G W  +  +S CSR C GG + + R C+ P P +GGRFC G + + RSCN E C     D REE C  ++ K +    +P      P          C L C        Y +   + DGTPC P   DICV+G C + GCD ++ SK   D C +C G N +C      F+ ++     ++   RIP    N+ IK+VS   TP  D      D     ++N   V+   +      G ++ YSGS   VE I+   ++     ++++V    +  N P + Y + +     ++ FVW         C   C G       C +K D+    D  C    +P      C   C  RW  A +          C  +CG G   +  +C +        S+ E VE   C   DL  +P    +C G C    W Y  W                                               +CP+ CG  ++ R   C     G     + C       D++E              T       + LT+W    W+ CS SC    + R V C  ++    + DE +              H P+P     C  + C  W + +   CS  CG+G   +   C    N N +   VD+ +C      KP      C    C                              + ++ W    W  CS +C  G Q R + C  ++E ++         C  ++ P   + C   PCP W Y  W EC  +C  G + R V+C  P + Q L +  CD+ +K P+ ++C +    G   W    W  CS +CG G + R + C Y N +++++ +      P     C+V+PC T    W     +    +C  G+    V C  +    + + +C     PS    C+   C  Y W+A  W  +  P
Sbjct:  249 PRFVELMVTADAKMVRHHGRNLEHYILTIMSVVAAVYKDPSVGNLINIMIVKLIVIHNEQEGPNVNFYAATTLHN------FCVWQQSHNVLDDSHPSHHDTALLITREDICRAKDKCDTLGLAELGTMCDPYRSCSISEENGLSSAFTIAHELGHVFNMPHD-DNPKC-----REAGIKHQYH-VMAPTLNYDTSPWSWSKCSRKYITEFLDTGYGECLLDE-------PVGKTYDLPVKLP-GQLYNVNRQCELMFGPGSQVCPF----MKQCKRLWCTSAEGDHKGCRTQHMPLADGTDCGHGMYCKHGMCVNKEIESRPVHGEWGPWGPYSVCSRTCGGGTRSTSRDCNKPAPKNGGRFCVGRRMKFRSCNTEPCPRDQKDFREEQCSHFDGKHFNINGLPPTIRWVPKYSGILMKDRCKLFCRVAGTMAYYQLRDRVVDGTPCGPDTYDICVQGLCRQAGCDHVLNSKARNDKCGVCGGDNSSCRTVAGTFNNAQYGYNVVV---RIPAGATNIDIKQVSYSGTPEDDNYLALSDSRSNFLLNGNLVVSMFKREISFKGTEIEYSGSNTTVERINCTERIE--DELILQVLCVGSLYN-PDVRYSFNIPIEEQREQFVWD-TSGPWQECSRMCQGERRRKAVCVRKSDHLVVSDQRCELLPRPRGATESCNTDCELRWHVAGK--------SECSSKCGPGYRTVEVLCMRYRQ---TKSVSEKVEVRACG--DLT-KPQSRESCHGDCLQKSWQYSAWSQFVNKCYIYILKSIKSQILMDLKVFLCSCFEMRAGKFYTESLHLCLQCPVTCGHGYQIRAVRCVSGSYGKTVDDQECNAASRPQDSQECELPACPRISSPVSTSRPAAPGQLLTQWRYGSWTTCSVSCGKGERARYVSCRDAQGG--VADESYC------------AHLPRPPETSVC-FSPCGHWREGEWSSCSVSCGVGRSTRQVVC---MNYNQQ---VDESYCHPDE--KP-STEQECAAVPCHSVYTHWPNNQPYFPYDPGSHPGHSSWNVPSADNQWRTGPWGSCSSTCEGGFQRRVVVC-QDSEGRS------TNYCDERVKPSESKSCDSGPCPLWNYGIWGECTQSCGGGQRTRLVVCQRP-NGQRLNEHNCDMLDKPPDVEQCNMQPCPGSASWHRRPWKSCSVTCGKGTRQRELACVYHNQTQTMEENCAHLPRPKTHKPCRVEPCPT----WKTNKWKACPVSCGAGVQTREVYCRLKGKGRIEEERCDAHIRPSSLQSCMLPDCHHYTWSATEWKEVSTP 1464

HSP 2 Score: 196.438 bits (498), Expect = 8.135e-50
Identity = 200/790 (25.32%), Postives = 303/790 (38.35%), Query Frame = 1 
Query: 2518 SCPIRCGTGKVKIPFVCQKINNQDDNNSLWETVEENLCFAVDLVDRPIEELNCVGQCNPLLWSYGKWEECPIECGTTFRYRNFICKDNKGLEWQKEWCERHLGLPDNKETCL-----------------------------SFNNCRNLTRWVTSPWSRCSNSCESELQKRMVYCFRSE-KSDEILDEKFLKIHEQISDAFCDIHSPKPITERPCSLNSCYFWIXXXXXXXXXXXXLGFRIQSHECKKKFNKNHEMITVDDKFCLKQNLVKPLDVRMRCFLKKCAIESFWIEMEWSKCSVSCGEGLQYRSLKCGYENENKTLTTWDNNEMCKNKMVPVSIQICKVTPCPKWIYSEWSECEGTCEYGSQHRTVLCTDPISEQILPDSKCDIKNKFPNFQKCLLSKLCGH--WIVGKWSQCSASCGLG----VKTRTITCNYSNGSKSID---HSVCKSVAPFEEIHCQVKPCSTNAFWWLVKPSECYEYNCQPGIMYAHVRCVNRKFQVLYDSKCSRIKHPSYYVGCLNTTCRRY-FWTAESWDNIPCPDISCTMKIRNRDVYCVDDYGNIQKDAMCDQSDKPDTWRLCPSPQNCSNIPRSCKELKSRQSVSKDGEYSLAIDLNWAYFIYCADMNTEEPKEYLTLREL---NYARTSKYVSTDVSSCIYEEEMEFNQKCPTCKINENLWSITYYNKIRINLSDLSIDVMDDRFSATNGQSFIPFGTAKDCAGSTSCPKGHFKINLRGTGFSVSMETRWNEVYPKYGYRILRKQTSQIVKGWCGGHCSGCSP 4758
            +C + CG G+      C+               +E+ C  +    RP E   C   C    W  G+W  C + CG     R  +C  N   +  + +C      P  ++ C                              S+N      +W T PW  CS++CE   Q+R+V C  SE +S    DE+                  KP   + C    C  W     G+C+  CG G R +   C++   +       D        L KP DV  +C ++ C   + W    W  CSV+CG+G + R L C Y N+ +T+      E C +   P + + C+V PCP W  ++W  C  +C  G Q R V C      +I  + +CD   +  + Q C+L   C H  W   +W + S    L     VK   ++     GS  +      + + V       C V  C       +V    C      P +     +                   P     C    C  + +W    W        +C   +  R V C++      K  +C  S KP +   C   Q    +  SC+EL+ R+ + KDGE+ L++   +   IYCA+M T  PKEY+TLR     NY+    Y   +   C Y       Q C  C+ +      T ++++R++LS + I   D +FS T     +PF TA DC  +  CP+G F INL GTG  V+  T+W         ++ R +    + G CGG C  C P
Sbjct: 1090 TCSVSCGKGERARYVSCRDAQGG--------VADESYCAHLP---RPPETSVCFSPCG--HWREGEWSSCSVSCGVGRSTRQVVCM-NYNQQVDESYCHPDEK-PSTEQECAAVPCHSVYTHWPNNQPYFPYDPGSHPGHSSWNVPSADNQWRTGPWGSCSSTCEGGFQRRVVVCQDSEGRSTNYCDERV-----------------KPSESKSCDSGPCPLWNYGIWGECTQSCGGGQRTRLVVCQRPNGQRLNEHNCD-------MLDKPPDVE-QCNMQPCPGSASWHRRPWKSCSVTCGKGTRQRELACVYHNQTQTM-----EENCAHLPRPKTHKPCRVEPCPTWKTNKWKACPVSCGAGVQTREVYCRLKGKGRI-EEERCDAHIRPSSLQSCMLPD-CHHYTWSATEWKEVSTPLALTRAILVKIVVMSFALRYGSLQLPNYFQPLTEGVCCLFGFQCSVS-CGVGYQQRMVS---CSAVPSTPDLQVFAAQSYTHASPSECPEPPPSHTKP-----CQMPECPPHGYWKVGPWSKC---SQTCGAGMMERMVECLNAKHLPSK--ICPLSSKPTSQAACRLRQ--CELFSSCRELQIREGIRKDGEHYLSVKSKFIQ-IYCAEMQTNFPKEYVTLRSGQTDNYSEVFGYRLNNPFECPYNGSRR--QDC-ACRNDYPAVGYTLFHRVRLDLSTMRIITTDVQFSQTLLGHSVPFATAGDCYSAARCPQGQFSINLTGTGLKVAESTKWVSHGNYVSVKVHRSEDGTRIYGRCGGFCGKCLP 1812

HSP 3 Score: 89.7373 bits (221), Expect = 2.398e-17
Identity = 136/559 (24.33%), Postives = 205/559 (36.67%), Query Frame = 1 
Query: 2656 PIEELNCVGQCNPLLW-SYGKWEECPIECGTTFRYRNFICKDNKGLEWQKEWCERHLGLPDNKETCLSFNNCRNLTRWVTSPWSRCSNSCESELQKRMVYCFRSEKSDEILDEKFLKIHEQISDAFCDIHSPKPITERPCSLNSCYFWIXXXXXXXXXXXXLGFRIQSHECKKKFNKNHEMITVDDKFCLKQNLVKPLDVRM-RCFLKKCA---IESFWIEMEWSKCSVSCGEGLQYRSLKCGYENENKTLTTWDNNEMCKNKMVPVSIQICKVTPCPK-------------------WIYSEWSECEGTCEYGSQHRTVLCTDPISEQILPDSKCDIKNKFPNFQKCLLSKLCGHWIVGKWSQCSASCGLGVKTRTITCNYSNGSKSIDHSVCK-SVAPFEEIHCQVKPC-STNAFWWLVKPSECYEYNCQPGIMYAHVRCVNRKFQVLYDSKCSRIKHPSY---YVGCLNTTCRRYFWTAE--------SWDNIPCP----------DISCTMKIRNRDVYCVDDYGNIQKDAMCDQSDKPDTWRLC---PSPQNCS 4182
            PIEE     Q    +W + G W+EC   C    R +    + +  L    + CE    LP  +    S N    L RW  +  S CS+ C    +   V C R  ++  + ++  ++       A  D+  P+       S  SC+               L    Q     +  NK +  I       +K  ++  L V +  CF  +      ES  + ++   C V+CG G Q R+++C   +  KT+    +++ C     P   Q C++  CP+                   W Y  W+ C  +C  G + R V C D     +  +S C    + P    C     CGHW  G+WS CS SCG+G  TR + C   N ++ +D S C     P  E  C   PC S    W   +P   Y+    PG    +V   + +++      CS      +    V C ++  R   +  E        S D+ PCP            SC    R R V C    G    +  CD  DKP     C   P P + S
Sbjct:  831 PIEE-----QREQFVWDTSGPWQECSRMCQGERRRKAVCVRKSDHLVVSDQRCEL---LPRPRGATESCNTDCEL-RWHVAGKSECSSKCGPGYRTVEVLCMRYRQTKSVSEKVEVR-------ACGDLTKPQ-------SRESCH------------GDCLQKSWQYSAWSQFVNKCYIYILKS----IKSQILMDLKVFLCSCFEMRAGKFYTESLHLCLQ---CPVTCGHGYQIRAVRCVSGSYGKTV----DDQECNAASRPQDSQECELPACPRISSPVSTSRPAAPGQLLTQWRYGSWTTCSVSCGKGERARYVSCRD-AQGGVADESYCAHLPRPPETSVCF--SPCGHWREGEWSSCSVSCGVGRSTRQVVC--MNYNQQVDESYCHPDEKPSTEQECAAVPCHSVYTHWPNNQPYFPYDPGSHPGHSSWNVPSADNQWRTGPWGSCSSTCEGGFQRRVVVCQDSEGRSTNYCDERVKPSESKSCDSGPCPLWNYGIWGECTQSCGGGQRTRLVVCQRPNGQRLNEHNCDMLDKPPDVEQCNMQPCPGSAS 1338
[Close]
BLAST of A disintegrin and metalloproteinase with thrombospondin motifs vs. Ensembl Sea Lamprey
Match: ENSPMAT00000009765.1 (pep scaffold:Pmarinus_7.0:GL478392:8852:44628:-1 gene:ENSPMAG00000008816.1 transcript:ENSPMAT00000009765.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 174.481 bits (441), Expect = 1.403e-45
Identity = 162/649 (24.96%), Postives = 267/649 (41.14%), Query Frame = 1 
Query: 1060 IMSTSLFFEYYPFIWSVCSQNVINSFLK---SKYSFCLKQRNRHRNLYPHEQINEFFQKYSTGVDYDLNEQCSFAFGEKSEFCETDQNSRKKCSVLYCRLKRYPICLRADAIIADGTECDVNQHCINGKCLYKNITIAPIDGGWSEYSEWSNCSRPCNGGVQFSYRTCDNPVPADGGRFCTGTKERIRSCNIEECSSFS-DPREESCGKYNLKPYIPTNDEEFP---------CNLVC--ITTNHSLKYDISLTDGTPCSPFRS--DICVKGTCYKTGCDRIVGSKKAIDNCNICAGQNDTCFKKESFFDGSKVAKVRMIRAFRIPPNVYNLFIKKVSQRMTPFTDEVYDDFELLLVVNRRTVIRRSETIEPLAGGQLRYSGSKNKVETISIKGKL--NVGISIVIKVENTKTTLNLPFISYHYFVK-------DI----FVWKYLEVITHPCKDQCGGFIEISPACFKKRDNQRYVDHYCSKATKPEPKIIKCGAICGYRWQRATEHYINSTVNKSCPIRCGTGKVKIPFVCQKINNQDDNNSLWETVEENLCFAVDLVDRPIEELNCVGQCNPLLWSYGKWEECPIECG-TTFRYRNFICKDNKGLEWQKEWCE---RHLGLPDNKETCLSFNNCRNLTRWVTSPWS 2904
            IMS  L ++  P  WS CS+  I  FL+     + FCL          P +  +        G  YD+N+QC   +G  S FC+   +    C  L+C +     C        +GT+C  ++ C +G+C+        ++G W  +S WS+C+R C  GVQ + R C+NP P  GGR+C G ++R R+CN++ CS+     R+  C +++  PY     +  P         C L C  +    S K   ++ DGTPC    +  D+C+ G C   GCD  + S    D C +C G   +C   +  ++  +   +  +    IP    ++ +++V++          D     L  N   VI+ +   +  AG    Y+ S N +E ++  G     V I ++ + +N       P I Y Y ++       DI      W Y+      C   CG  ++       +R      + +C+  T+P+ +   C        Q     YI     K+  I    GK+   + C     Q  ++ L  T+  NL      +D+      CV  C   +W  G W++C   CG     +R  +C  + G + QK       +HL  P  + +C     C   +RWV   W+
Sbjct:   22 IMSPQLLYDTSPLTWSRCSKEYITRFLEMPSRGWGFCLDDG-------PAKPHDLSVPSLPPGSLYDVNQQCRLQYGPDSRFCDGVDDV---CRTLWCTVGS--TCHSKMDAAVEGTKCGEDKWCFHGECVTVAQRSGSVNGDWGAWSSWSHCTRTCGVGVQSALRKCNNPTPRFGGRYCVGERKRYRTCNVQPCSADGLSFRQMQCSEFDTVPYRSGLHKWAPLFGTVEPNSCELHCRPMVGYFSEKMLDAVIDGTPCYEGNASRDVCIDGICKNVGCDYEIDSNAMEDRCGVCQGNGSSCETVKMTYE--ETEGLGYVDVGLIPEGARDIRVEEVAEASNFLALRSEDPARYFL--NGDWVIQWNGDYK-AAGTTFTYARSGN-LENLTAPGPTMEPVWIQLLFQEKN-------PGIRYEYTIRKDTDSDNDIAPPELFWHYMPW--SKCTVTCGAGVQRQTVSCLERTAGIVEEKFCNSTTRPDDRQRACNE------QDCPSRYIFCIDFKTSSIGFAGGKLLFRWECV----QTRSHKLHRTMLHNLQSVTGNIDQITA---CVYLCCMPMWWAGDWQKCSATCGRNGTAHRTVLCLRSIGPDAQKALPNSECQHLPKPKLQSSCNQHVPCP--SRWVVGNWT 628

HSP 2 Score: 52.373 bits (124), Expect = 9.388e-7
Identity = 50/194 (25.77%), Postives = 71/194 (36.60%), Query Frame = 1 
Query: 3286 ESFWIEMEWSKCSVSCGEGLQYRSLKC-----GYENE---NKTLTTWDNNEMCKNKMVP---------------------------------------------VSIQICKVTPC------PKWIYSEWSECEGTC-EYGSQHRTVLC---TDPISEQILPDSKCDIKNKFPNFQKCLLSKLC-GHWIVGKWSQ 3675
            E FW  M WSKC+V+CG G+Q +++ C     G   E   N T    D    C  +  P                                             V+  I ++T C      P W   +W +C  TC   G+ HRTVLC     P +++ LP+S+C    K      C     C   W+VG W++
Sbjct:  436 ELFWHYMPWSKCTVTCGAGVQRQTVSCLERTAGIVEEKFCNSTTRPDDRQRACNEQDCPSRYIFCIDFKTSSIGFAGGKLLFRWECVQTRSHKLHRTMLHNLQSVTGNIDQITACVYLCCMPMWWAGDWQKCSATCGRNGTAHRTVLCLRSIGPDAQKALPNSECQHLPKPKLQSSCNQHVPCPSRWVVGNWTE 629
[Close]
BLAST of A disintegrin and metalloproteinase with thrombospondin motifs vs. Ensembl Sea Lamprey
Match: adamtsl3 (ADAMTS-like 3 [Source:ZFIN;Acc:ZDB-GENE-121030-8])

HSP 1 Score: 160.229 bits (404), Expect = 1.566e-39
Identity = 205/893 (22.96%), Postives = 323/893 (36.17%), Query Frame = 1 
Query: 1471 DGGWSEYSEWSNCSRPCNGGVQFSYRTCDNPVPADGGRFCTGTKERIRSCNIEEC-SSFSDPREESCGKYN-------LKPYIPT-NDEEFPCNLVCITTNHSLKYDIS--LTDGTPCSPFRSDICVKGTCYKTGCDRIVGSKKAIDNCNICAGQNDTCFKKE-SFFDGSKVAKVR-MIRAFRIPPNVYNLFIKKVSQRMTPFTDEVYDDFELLLVVNRRTVIRRSETIEPLAGGQLRYSGSKNKVE------TISIKGKLNVGISIVIKVENTKTTLNLPFISYHYFVKDIFVWKYLEVITHPCKDQCGGFIEISPA-CFKKRDNQRYVDHYCS---KATKPEPKIIKCG-----AICGYRWQRATEHYI--------NSTVNKSCPIRCGTGKVKIPFVCQKINNQDDNNSLWETVEENLCFAV--DLVDRPIEELNCVGQCNPLLWSYGKWEECPIECGTTFRYRNFICKDNKGLEWQKEWCERHLG------LPDNKETCLSFNNC----------------RNLTRWVTSP------------WSRCSNSCESELQKRMVYCFRSEKSDEILDEKFLKIHEQISDAFCDIHSPKPITERPCSLNSCYFWIXXXXXXXXXXXXLGFRIQSHECKKKFN---------------KNHEMITV----------DDKFCLKQNLVKPLDVRMRCFLKKCAIESFWIEMEWSKCSVSCGEGLQYRSLKCGYENENKTLTTWDNNEMCK-NKMVPVSIQICKVTPC-PKWIYSEWSECEGTC-EYGSQHRTVLC--------TDPISEQILPDSKCDIKNKFPNFQKCLLSKLCGHWIVGKWSQCSASCGLGVKTRTITCNYSNGSKSI---DHSVCKSVA-PFEEIHCQVKPC 3813
            D  W  +  WS CSR C GG  +S R C        GR C G   R +SC+ E+C +   D R + C  +N        + + P     E PC L C+    SL  ++S  + DGT C+P   D+C+ G C    C      K+   N     G  D  F  E +F   SK+ K    + A         + +K   Q                L+V  +T+  R   I   + G      S  + +       + I G +    +I  +  ++  T+ L F+ Y          ++ E    PC   CGG  +++ A C   R+ +   DH+C+   +  KP+P++ +C      +  G++   + +HY           +   +C   CG G       C     ++D     E VEE  C  V    V +P    +C        W   +W  C + CG   +YR  +C D++G         +H G       P  KE CL    C                +     +  P            WS CS SC   ++ R V C        +L   F +   ++ D  C+    +P +ERPC+L  C                L  R Q  +    F+                N E I +          D+  C      +P  ++  C    C   S W   EW  CS SCG GL+ RS+ C      +   + +           P  ++ C  + C P W   +W  C  TC   G Q R++ C        +  + EQ+ PDS+   +      Q    S+    W+  +W Q +   G   + R ++C +S  +++    + S C S+  P     C + PC
Sbjct:   35 DPTWDAWGPWSECSRTCGGGASYSIRRC------LAGRSCVGQTIRYKSCSTEDCPADAGDFRAQQCSAHNDVKFRGQYREWQPVYEGAEKPCALYCVARGTSLVEELSPKVLDGTRCAPGSLDMCISGICQALCCIHKKLVKRHNRNVRNTLGSTDQDFCIEGTFLSVSKITKTEDTVIAIPFGSRQIKITVKGPDQ----------------LLVETKTLQGRRGEISLTSAGTFSLENSSLEFQRHPGKRVLHITGPIQADFTIKARHVSSAETVVL-FLFYQPIPH-----QWRETDFFPCSSSCGGGYQLTSAECVDMRNARIASDHFCNYYPENKKPKPRLRECSMEPCPSSDGFKQIMSYDHYQPLPRPCRWEGSPWTACSSSCGGGVQSRSVSCV----EEDQQGHLEPVEEWKCMYVLRPAVTQPCNLYDCPK------WMAQEWSSCTVTCGRGLKYRVVLCIDHRG---------QHTGGCNTKIKPHVKEECLVTTPCYKPREKLPVEAKVPWFKQAQELIEGPAVSEEAAFAPDAWSPCSRSCGPGVRTRAVRC-------RVL-LPFSRSVVELPDGECE--GERPASERPCALGPCVE-AADGLLTDEEAQALEERGQGGDEALAFDWEYGGFSHCSVSCAGGNREAIVICVNKETGEAEDESLCDAD--ARPPQIQRPCHTLPCP--SRWETSEWGACSASCGAGLRARSVGCARTVAREADGSEERQRATDCTGPRPPDVEPCARSDCPPAWHARDWQPCSRTCGSSGVQSRSLRCRRLLADGSSRDVDEQLCPDSRPLAQQACGGGQ----SECPAEWVASEWGQINTHQGNYTQHRDVSCQFSTAAEATSVANASQCSSLPKPLASRACTLPPC 861

HSP 2 Score: 90.8929 bits (224), Expect = 2.380e-18
Identity = 62/217 (28.57%), Postives = 93/217 (42.86%), Query Frame = 1 
Query: 3193 MITVDDKFCLKQNLVKP-LDVRMRCFLKKCAIESFWIEMEWSKCSVSCGEGLQYRSLKCGYENENKTLTTWDNNEMCKNKMVPVSIQICKVTPCPKWIYSEWSECEGTC---EYGSQHRTVLCTDPISEQILPDSKCDIKNKFPNFQKCLLSKLCGHWIVGKWSQCSASCGL-GVKTRTITCNYSNGSKSIDHSVCK-SVAPFEEIHCQVKPCSTNA 3825
            +  V D FC    L +P L     C    C  + +W+   WS CS +CG G++ RS+ C        L  +     C+    P   + CK   CP+W    W+EC G C     G+QHR VLC    +    P+  C  K +  + Q C +      W  G W+ C+ASCG  G + R + C +   ++    + C     P     C + PC+T +
Sbjct: 1539 VTVVSDAFC--SLLPRPQLPTNSPCPAVGC--QPWWVTGPWSDCSEACGAGVRVRSVVCRSPAGATALPDYS----CRGAERPARAEPCKRHGCPEWAVGAWAECTGRCVGLGIGTQHRRVLCFL-HNGTAAPEGDCASKARPGSVQNCSVEACAVQWRTGPWAVCTASCGTHGFQARRVECAHVRTARPAPDAHCAWQHKPATWQRCNITPCATTS 1746

HSP 3 Score: 84.3445 bits (207), Expect = 2.478e-16
Identity = 83/328 (25.30%), Postives = 120/328 (36.59%), Query Frame = 1 
Query: 3295 WIEMEWSKCSVSCGEGLQYRSLKCGYENENKTLTTWDNNEMCKNKMVPVSIQICKVTPCPKWIYSEWSECEGTCEYGSQHRTVLCTDP---------------ISEQIL-------PDSKCDIKNKFPNFQKC--LLSKLC----GHWIVGKWSQCSASCGLGVKTRTITCN----YSNGSKSIDHSVCKSVAPFEEIHCQVKPC------------------------STNAFWWLVKPSECYEYNCQPGIMYAHVRCVNRKFQVL-------YDSKCSRIKHPSYYVGCLNTTCRRYFWTAESWDNIPCPDISCTMKIRNRDVYCV 4089
            W    W+ CS SCG G+Q RS+ C  E++   L   +  + C   + P   Q C +  CPKW+  EWS C  TC  G ++R VLC D                + E+ L       P  K  ++ K P F++   L+          +    WS CS SCG GV+TR + C     +S     +    C+   P  E  C + PC                           AF W          +C  G   A V CVN++            D++  +I+ P + + C +       W    W        SC   +R R V C 
Sbjct:  385 WEGSPWTACSSSCGGGVQSRSVSCVEEDQQGHLEPVEEWK-CMYVLRPAVTQPCNLYDCPKWMAQEWSSCTVTCGRGLKYRVVLCIDHRGQHTGGCNTKIKPHVKEECLVTTPCYKPREKLPVEAKVPWFKQAQELIEGPAVSEEAAFAPDAWSPCSRSCGPGVRTRAVRCRVLLPFSRSVVELPDGECEGERPASERPCALGPCVEAADGLLTDEEAQALEERGQGGDEALAFDWEYGGFSHCSVSCAGGNREAIVICVNKETGEAEDESLCDADARPPQIQRPCHTLPCPSR------WETSEWGAC---SASCGAGLRARSVGCA 702

HSP 4 Score: 55.0694 bits (131), Expect = 1.747e-7
Identity = 55/248 (22.18%), Postives = 88/248 (35.48%), Query Frame = 1 
Query: 3448 QICKVTPCPKWIYSEWSECEGTCEYGSQHRTVL---CTDPISEQILPDSKCDI--KNKFPNFQKCLLSKLCGHWIVGKWSQCSASCGLGVKTRTITCNYSNGSKSIDHSVCKSVAPFEEIHCQVKPCSTNA--FWWLVKPSECYEYNCQPGIMYAHVR--CVNRKFQVLYDSKCSRIKHPSYYVGCLNTTCRRYFWTAESWDNIPCPDISCTMKIRNRDVYCVD-DYGNIQKDAMCDQSDKPDTWRLC 4161
            ++  V P  +W  ++ + C  +C   S           D ++  ++ D+ C +  + + P    C        W+ G WS CS +CG GV+ R++ C    G+ ++    C+      E   + +PC  +    W +   +EC       GI   H R  C         +  C+    P     C    C    W    W    C     T   + R V C          DA C    KP TW+ C
Sbjct: 1499 KVALVLPEHRWFVNDTASCPASCGNASARGAPAPRCVRDNVT--VVSDAFCSLLPRPQLPTNSPCPAVGCQPWWVTGPWSDCSEACGAGVRVRSVVCRSPAGATALPDYSCRGA----ERPARAEPCKRHGCPEWAVGAWAECTGRCVGLGIGTQHRRVLCFLHNGTAAPEGDCASKARPGSVQNCSVEAC-AVQWRTGPWAV--CTASCGTHGFQARRVECAHVRTARPAPDAHCAWQHKPATWQRC 1737

HSP 5 Score: 53.5286 bits (127), Expect = 4.761e-7
Identity = 53/215 (24.65%), Postives = 86/215 (40.00%), Query Frame = 1 
Query: 2884 WVTSPWSRCSNSCESELQKRMVYCFRSEKSDEILDEKFLKIHEQISDAFCDIHSPKPITERPCSLNSCYFW-IXXXXXXXXXXXXLGFRIQSHECKKKFNKNHEMITVDDKFCLKQNLVKPLDVRMRCFLKKCAIESFWIEMEWSKCSVSCG-EGLQYRSLKCGYENENKTLTTWDNNEMCKNKMVPVSIQICKVTPCPKWIYSEWSECEGTCEY 3522
            WVT PWS CS +C + ++ R V C RS      L +   +  E            +P    PC  + C  W + + +       GLG   Q    ++     H      +  C  +   +P  V+  C ++ CA++  W    W+ C+ SCG  G Q R ++C +    +       +  C  +  P + Q C +TPC     +  SEC  +  Y
Sbjct: 1570 WVTGPWSDCSEACGAGVRVRSVVC-RSPAGATALPDYSCRGAE------------RPARAEPCKRHGCPEWAVGAWAECTGRCVGLGIGTQH---RRVLCFLHNGTAAPEGDCASK--ARPGSVQ-NCSVEACAVQ--WRTGPWAVCTASCGTHGFQARRVECAHVRTARPAP----DAHCAWQHKPATWQRCNITPC-----ATTSECRDSSRY 1754
[Close]
BLAST of A disintegrin and metalloproteinase with thrombospondin motifs vs. Ensembl Sea Lamprey
Match: ENSPMAT00000007886.1 (pep scaffold:Pmarinus_7.0:GL477456:619503:639284:-1 gene:ENSPMAG00000007122.1 transcript:ENSPMAT00000007886.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 142.895 bits (359), Expect = 1.022e-34
Identity = 114/439 (25.97%), Postives = 175/439 (39.86%), Query Frame = 1 
Query:  775 FCHWVRQKKQLWNYSWDS---AILIND----GVFSSNAIGIAHLRSMCN-DNNCLAVVDRGFGTGFIIAHELAHQMNARHDFDNAEACSFFEKQYDNKTKYNTIMSTSLFFEYYPFIWSVCSQNVINSFLKSKYSFCLKQRNRHRNLYPHEQINEFFQKYSTGVDYDLNEQCSFAFGEKSEFCETDQNSRKKCSVLYCRLK-------------RYPICLRADAIIADGTECDVNQHCINGKCLYKNITIAPIDGGWSEYSEWSNCSRPCNGGVQFSYRTCDNPVPADGGRFCTGTKERIRSCNIEECS-----SFSDPREESCGKYNLK-----------------------PYIPTNDEEFPCNLVCITTNHSLKYDIS--LTDGTPC-SPFRSDICVKGTCYKTGCDRIVGSKKAIDNCNICAGQNDTCFKKESFF 1935
            FC W  Q++++   +  +   A+L+      G  S + +G+A + ++C+   +C  + D G    + +AHE+ H +   HD   ++AC            +  IMS +L        WS CS  +++    S  + CL        L    Q       ++ G  Y  + QC  AFG  +  C         C+ L+C +              R  +C+      A GT C   + C +G C       + +DGGW  +  W  CSR C GG Q S R CD+P P   G +C G + R RSC+   C      SF   REE C ++N                         P +        C L+C     +  Y  +  + DGT C +     +CV+G C  TGCD  +GS+ A D C +C G   +C      F
Sbjct:  260 FCAW--QRREMRGGAGPAHHVAVLLTRQELCGAHSCHTLGMADVGTVCDPQRSCAVIRDHGMTAAYTMAHEIGHILGLPHD--ESKACIKIMSPSGRPRAH--IMSATLAHVDPARPWSPCSAALLDDIFHSGGADCLLSAPAAPPLSTGHQAEP--TPFTPGARYPASVQCRLAFGPGARVCAHT----APCAKLWCAVPGATLESGTGGARHRGKVCVTRHLPWAQGTACGHGRWCSHGVCTSAEQRASDVDGGWGGWGPWGPCSRSCGGGAQVSPRACDSPAPRGHGAYCGGARVRYRSCHARACQLATGLSF---REEQCAQHNSASAKGAPEPPGPPGARASRPVLWVPKVSGVALADRCKLLCRANGTAYYYMFARRVVDGTACGAEPGGGVCVEGQCVPTGCDGTLGSRAARDRCGVCRGDGSSCTLVSGVF 683
[Close]
BLAST of A disintegrin and metalloproteinase with thrombospondin motifs vs. Ensembl Sea Lamprey
Match: ENSPMAT00000007884.1 (pep scaffold:Pmarinus_7.0:GL477456:619446:639227:-1 gene:ENSPMAG00000007122.1 transcript:ENSPMAT00000007884.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 140.584 bits (353), Expect = 4.887e-34
Identity = 114/439 (25.97%), Postives = 178/439 (40.55%), Query Frame = 1 
Query:  775 FCHWVRQKKQLWNYSWDS---AILIND----GVFSSNAIGIAHLRSMCN-DNNCLAVVDRGFGTGFIIAHELAHQMNARHDFDNAEACSFFEKQYDNKTKYNTIMSTSLFFEYYPFIWSVCSQNVINSFLKSKYSFCLKQRNRHRNLYPHEQINEFFQKYSTGVDYDLNEQCSFAFGEKSEFCETDQNSRKKCSVLYCRLK-------------RYPICLRADAIIADGTECDVNQHCINGKCLYKNITIAPIDGGWSEYSEWSNCSRPCNGGVQFSYRTCDNPVPADGGRFCTGTKERIRSCNIEECS-----SFSDPREESCGKYNLK-----------------------PYIPTNDEEFPCNLVCITTNHSLKYDIS--LTDGTPC-SPFRSDICVKGTCYKTGCDRIVGSKKAIDNCNICAGQNDTCFKKESFF 1935
            FC W  Q++++   +  +   A+L+      G  S + +G+A + ++C+   +C  + D G    + +AHE+ H +   HD   ++AC     +   + + + IMS +L        WS CS  +++    S  + CL        L    Q       ++ G  Y  + QC  AFG  +  C         C+ L+C +              R  +C+      A GT C   + C +G C       + +DGGW  +  W  CSR C GG Q S R CD+P P   G +C G + R RSC+   C      SF   REE C ++N                         P +        C L+C     +  Y  +  + DGT C +     +CV+G C  TGCD  +GS+ A D C +C G   +C      F
Sbjct:  241 FCAW--QRREMRGGAGPAHHVAVLLTRQELCGAHSCHTLGMADVGTVCDPQRSCAVIRDHGMTAAYTMAHEIGHILGLPHD--ESKAC----IKIIGRPRAH-IMSATLAHVDPARPWSPCSAALLDDIFHSGGADCLLSAPAAPPLSTGHQAEP--TPFTPGARYPASVQCRLAFGPGARVCAHT----APCAKLWCAVPGATLESGTGGARHRGKVCVTRHLPWAQGTACGHGRWCSHGVCTSAEQRASDVDGGWGGWGPWGPCSRSCGGGAQVSPRACDSPAPRGHGAYCGGARVRYRSCHARACQLATGLSF---REEQCAQHNSASAKGAPEPPGPPGARASRPVLWVPKVSGVALADRCKLLCRANGTAYYYMFARRVVDGTACGAEPGGGVCVEGQCVPTGCDGTLGSRAARDRCGVCRGDGSSCTLVSGVF 661
[Close]
BLAST of A disintegrin and metalloproteinase with thrombospondin motifs vs. Ensembl Sea Lamprey
Match: paplna (papilin a, proteoglycan-like sulfated glycoprotein [Source:ZFIN;Acc:ZDB-GENE-070815-4])

HSP 1 Score: 134.035 bits (336), Expect = 3.095e-32
Identity = 135/568 (23.77%), Postives = 211/568 (37.15%), Query Frame = 1 
Query: 1480 WSEYSEWSNCSRPCNGGVQFSYRTCDNPVPADGGRFCTGTKERIRSCNIEECSSFSDP-REESCGKYNLKPY-------IPTNDEEFPCNLVCITT--NHSLKYDISLTDGTPCSPFRSDICVKGTCYKTGCDRIVGSKKAIDNCNICAGQNDTCFKKESFFDGSKVAKVRMIRAFRIPPNVYNLFIKK-VSQRMTPFTDEVYDDFELLLVVNRRTVIRRSETIEPLAGGQLRY---SGSKNKVETISIKGKLNVGISI-VIKVENTKTTLNLPFISYHYFV-----KDIFVWKYLEVITHPCKDQCGGFIEISPACFKKR------DNQRYVDHYCSKATKPEPK----IIKCGAICGYRWQRATEHYINSTVNKSCPIRCGTGKVKIPFVCQKINNQDDNNSLWETVEENLCFAVDLVDRPIEELNCVGQCNPLLWSYGKWEECPIECGTTFRYRNFICKDNKGLEWQKEWCERHLGLPDNKETCLSFNNCRNLTRWVTSPWSRCSNSCESELQKRMVYCFRSEKSDEILDEKFLKIHEQISDAFCDIHSPKPITERPCSLNSCYF 3093
            W  + +W+ CSR C GG+    R C   +  DG   C G+    R+CN++ C   S P R   C +++  P+       +P +     C L C+    N   ++ +++ DGTPC   +SD CV+G C + GCD  + S +A D C +C G   TC+     F  S++        + +P    ++ IK+ +  R       +  ++ L    N    +  S+T    AG  + Y    GS    +++   G     + + +I  E  K       I Y YF+     +    + +       C  +C G +      F+ R      DN+   D YC+   +P          C A+   RW+             SC + CG G+   P  C          +     +E+ C A  L   P    +C  Q  P  W  G WE C   CGT  + R   C        Q   C      P  ++ C           W   PW  CS SC   L+KR   C+  +   E++D +                   P  E  C+   CY 
Sbjct:    7 WGPWGDWAACSRSCGGGITHRERPCLY-LRDDGQPECFGSTRMYRTCNVQACPEGSRPFRNVQCSEFDEVPFEGRTYKWVPYHGGTKRCELNCMPKGENFYFRHALAVIDGTPCELGKSDKCVEGICMRVGCDGELESDRAEDKCRVCGGDGRTCYPVSGVFTKSQLPIGATATWWLVPAGATSILIKEMIPSRNFLAVRTLRGEYHL----NGDWTVDYSQTFT-AAGTTVEYDRSEGSHRSAQSVHASGPTTEPLLVELISQEENKG------IHYEYFMPAKRNRAQLGYGWSHGSWGSCGKECSGGLPG----FQTRTVYCSSDNEVLPDAYCAGDIRPASNRSCNTDPCPAV--IRWRVGDW--------GSCSVTCGAGEQTRPVRCMS-----SGPAAAAPADESACLA-SLGPAPASRQSCSLQPCPQ-WIIGSWEPCSATCGTGVQTRAVTCGPPAPRGAQLARCS-PASTPPARQPCERAACPARSFGWFEGPWGLCSVSCGGGLRKRQALCYNEDF--EVMDPRMCGEEGH------------PTEEEGCNTQPCYL 526

HSP 2 Score: 98.9821 bits (245), Expect = 3.484e-21
Identity = 68/243 (27.98%), Postives = 95/243 (39.09%), Query Frame = 1 
Query: 3295 WIEMEWSKCSVSCGEGL---QYRSLKCGYENENKTLTTWDNNEMCKNKMVPVSIQICKVTPCP---KWIYSEWSECEGTCEYGSQHRTVLC--TDPISEQILPDSKC--DIKNKFPNFQKCLLSKLCGHWIVGKWSQCSASCGLGVKTRTITCNYSNGSKSIDHSVCKSVAPFEEIHCQVKPCSTNAFWWLVKPSECYEYNCQPGIMYAHVRCVNRKFQVLYDSKCSRIKHPSYYVGCLNTTC 3993
            W    W  C   C  GL   Q R++ C  +NE         +  C   + P S + C   PCP   +W   +W  C  TC  G Q R V C  + P +     +S C   +     + Q C L + C  WI+G W  CSA+CG GV+TR +TC       +       +  P     C+   C   +F W   P      +C  G+      C N  F+V+    C    HP+   GC    C
Sbjct:  289 WSHGSWGSCGKECSGGLPGFQTRTVYCSSDNEVLP------DAYCAGDIRPASNRSCNTDPCPAVIRWRVGDWGSCSVTCGAGEQTRPVRCMSSGPAAAAPADESACLASLGPAPASRQSCSL-QPCPQWIIGSWEPCSATCGTGVQTRAVTCGPPAPRGAQLARCSPASTPPARQPCERAACPARSFGWFEGPWGLCSVSCGGGLRKRQALCYNEDFEVMDPRMCGEEGHPTEEEGCNTQPC 524

HSP 3 Score: 93.2041 bits (230), Expect = 2.244e-19
Identity = 60/208 (28.85%), Postives = 84/208 (40.38%), Query Frame = 1 
Query: 3202 VDDKFCLKQNLVKPLDVRMRCFLKKCAIESFWIEMEWSKCSVSCGEGLQYRSLKCGYENENKTLTTWDNNEMCKNKMVPVSIQICKVTPCPKWIYSEWSECEGTCEYGSQHRTVLCTDPISEQILPDSKCDIKNKFPNFQKCLLSKLCGH---WIVGKWSQCSASCGLGVKTRTITCNYSNGSKSIDHSVCKSVA-PFEEIHCQVKPC 3813
            + D +C     ++P   R  C    C     W   +W  CSV+CG G Q R ++C            ++  +      P S Q C + PCP+WI   W  C  TC  G Q R V C  P        ++C   +  P  Q C  +        W  G W  CS SCG G++ R   C Y+   + +D  +C     P EE  C  +PC
Sbjct:  322 LPDAYCAGD--IRPASNRS-CNTDPCPAVIRWRVGDWGSCSVTCGAGEQTRPVRCMSSGPAAAAPADESACLASLGPAPASRQSCSLQPCPQWIIGSWEPCSATCGTGVQTRAVTCGPPAPRGAQ-LARCSPASTPPARQPCERAACPARSFGWFEGPWGLCSVSCGGGLRKRQALC-YNEDFEVMDPRMCGEEGHPTEEEGCNTQPC 524

HSP 4 Score: 72.7886 bits (177), Expect = 4.866e-13
Identity = 73/291 (25.09%), Postives = 112/291 (38.49%), Query Frame = 1 
Query: 3478 WIYSEWSECEGTCEYGS---QHRTVLCTDPISEQILPDSKC--DIK---NKFPNFQKCLLSKLCGHWIVGKWSQCSASCGLGVKTRTITCNYSNGSKSI--DHSVCKSV---APFEEIHCQVKPCSTNAFWWLVKPSECYEYNCQPGIMYAHVRCVNRKFQVLYDSKCSRIKHPSYYVGCLNTTC--RRYFWTAESWDNIPCPDISCTMKIRNRDVYCVDDYGNIQKDAMCDQSDKPDTWRLCPSPQNCSNIPRSCKELKSRQSVSKDGEYSL-AIDLNWAYFIYCADMNT 4302
            W +  W  C   C  G    Q RTV C+     ++LPD+ C  DI+   N+  N   C        W VG W  CS +CG G +TR + C  S  + +   D S C +    AP     C ++PC      W++   E     C  G+    V C     +    ++CS    P     C    C  R + W    W       +SC   +R R   C ++   +    MC +   P     C + Q C  +P+  +  K  Q+VS        ++ + +  F+Y    N+
Sbjct:  289 WSHGSWGSCGKECSGGLPGFQTRTVYCSS--DNEVLPDAYCAGDIRPASNRSCNTDPCPAVI---RWRVGDWGSCSVTCGAGEQTRPVRCMSSGPAAAAPADESACLASLGPAPASRQSCSLQPCPQ----WIIGSWEPCSATCGTGVQTRAVTCGPPAPRGAQLARCSPASTPPARQPCERAACPARSFGWFEGPWGLC---SVSCGGGLRKRQALCYNEDFEVMDPRMCGEEGHPTEEEGC-NTQPC-YLPQGGEPSKLIQTVSPPTRRPFKSVRIGFNNFVYKESRNS 565

HSP 5 Score: 69.707 bits (169), Expect = 4.156e-12
Identity = 69/262 (26.34%), Postives = 101/262 (38.55%), Query Frame = 1 
Query: 2701 WSYGKWEECPIECG---TTFRYRNFICK-DNKGLEWQKEWCERHLGLPDNKETCLSFNNCRNLTRWVTSPWSRCSNSCESELQKRMVYCFRSEKSDEILDEKFLKIHEQISDAFCDIHSPKPITERPCSLNSCYFWIXXXXXXXXXXXXLGFRIQSHECKKKFNKNHEMITVDDKFCLKQNLVKPLDVRMRCFLKKCAIESF-WIEMEWSKCSVSCGEGLQYRSLKCGYENENKTLTTWDNNEMCKNKMVPVSIQICKVTPC 3471
            WS+G W  C  EC      F+ R   C  DN+ L     +C   +  P +  +C + + C  + RW    W  CS +C +  Q R V C  S  +     ++          A      P P + + CSL  C  WI      CSA CG G + ++  C     +  ++         + +       R  C    C   SF W E  W  CSVSCG GL+ R   C Y  + + +    +  MC  +  P   + C   PC
Sbjct:  289 WSHGSWGSCGKECSGGLPGFQTRTVYCSSDNEVLP--DAYCAGDI-RPASNRSC-NTDPCPAVIRWRVGDWGSCSVTCGAGEQTRPVRCMSSGPAAAAPADE---------SACLASLGPAPASRQSCSLQPCPQWIIGSWEPCSATCGTGVQTRAVTCGPPAPRGAQLA--------RCSPASTPPARQPCERAACPARSFGWFEGPWGLCSVSCGGGLRKRQALC-YNEDFEVM----DPRMCGEEGHPTEEEGCNTQPC 524
[Close]
BLAST of A disintegrin and metalloproteinase with thrombospondin motifs vs. Ensembl Nematostella
Match: EDO44376 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RW19])

HSP 1 Score: 369.007 bits (946), Expect = 1.421e-104
Identity = 359/1298 (27.66%), Postives = 531/1298 (40.91%), Query Frame = 1 
Query:  529 VEPNIIELLIVVTSNFVKRF--KKDFRQYILSNVAIATKLLHDPTIKASITXXXXXXXXXXEDYERNNDLHDWSLLSQDRVVSR-FCHWVRQKKQLWNYS---WDSAILIND-----GVFSSNAIGIAHLRSMCNDNNCLAVVD-RGFGTGFIIAHELAHQMNARHDFDNAEACSFFEKQYDNKTKYNTIMSTSLFFEYYPFIWSVCSQNVINSFLKSKYSFCLKQRNRHRNLYPHEQINEFFQKYSTGVDYDLNEQCSFAFGEKSEFCETDQNSRKKCSVLYC--RLKRYPICLRADAIIADGTECDVNQHCINGKCLYKNITIAPIDGGWSEYSEWSNCSRPCNGGVQFSYRTCDNPVPADGGRFCTGTKERIRSCNIEECSSFS-DPREESCGKYNLKP-----------YIPTND---EEFPCNLVCITTNHSLKYDIS--LTDGTPCSPFRSDICVKGTCYKTGCDRIVGSKKAIDNCNICAGQNDTCFKKESFFDGSKVAKVRMIRAFRIPPNVYNLFIKKVSQRMTPFTDEVYDDFELL--------LVVNRRTVIRRSETIEPLAGGQLRYSGSKNKVETISIKGKLNVGISI-VIKV-----ENTKTTLNLPFISYHYFVKDIFVWKYLEVITHPCKDQCGGFIEISPACFKKRDNQRYVDHYCSKATKPEPKIIKCGAICGYRWQRATEHYINSTVNKSCPIRCGTGKVKIPFVCQKINNQDDNNSLWETVEENLCFAVDLVDRPIEELNCVGQCNPLLWSYGKWEECPIECGTTFRYRNFICKDNKGLEWQKEWCERHLGLPDN----KETCLSFNNCR-NLTRWVTSPWSR----CSNSCESELQKRMVYCFRSEKSDEILDEKFLKIHEQISDAFCDIHSPKPITERPCSLNSCYFWIXXXXXXXXXXXXLGFRIQSHECKKKFNKNHEMITVDDKFCLKQNLVKPLDVRMRCFLKKCAIESF------WIEMEWSKCSVSCG-EGLQYRSLKCGYENENKTLTTWDNNEMCKNKMVPVSIQICKVTPCPKWIYSEWSECEGTCEYGSQHRTVLCTDPISEQILPDSKCDIKNKFPNFQKCLLSK---LCGH-----------------------WIVGKWSQCSASCGLGVKTRTITCNYSNGSKSIDHSVCKSVAPFEEIHCQVKPCSTNAFWWLVKPSECYEYNCQPGIMYAHVRCVNRKFQVLYDSKCSRIKHPSYYVGCLNTTCRRYFWTAESWDNIPCPDISCTMKIRNRDVYCVDDYGNIQKDAMCDQSDKPDTWRLC 4161
            +E   +E ++    + V  F  K + + +I++ + +  ++  D TI  SI I +V I++L        DL +  + S      R FC W  +  +  +     +D+AIL+            + +G+A L ++CN +   ++V+  G  + F IAHELAH  N  HD D+           D K+    +M+ SL F   P++WS CS++ I  F    Y  CL+ +       P E+    F     G  Y  N+QC   FG +S  C         C  L+C   L +   C       ADGT C  ++ CI GKC+ KN  +  +DG W  ++ +  CSR C GG+QF+ R C+NP P +GG +C G ++R RSCN EEC   S D R   C + N KP           ++P      EE  C L C   +  + + +S  + DGTPC  F SD+CV G C   GCDRIVGS+   D C +C G N TC K +  +   K+A       ++IP    N+ I +   R         D+F  L         ++N  +V+   E    + G  + YSGS    E I I GK    + + V+ V      N   +LN+PFI  H F   I  W        PC   C G       C +  D +      C    +P     KC   C  RW+   E          C   CG GK K    C ++         W+ V    C     ++RP+  + C G+C    W Y +W +C   CG+  + R   C D+KG             LPD      +  L    C     +W  + W +    CS SC S +Q R+V C                IH    D+ C   + KP   + C+   C  W       CS  CG+G + +S  C  ++N      T  D+  L+ +L +      RC    C  ++F      W    WS+CS SCG +G + R + C    +++ +   +   +C     P + + C V PC  W +  W  C  +C  G Q R V C    + +I  DS+CD   + P  ++C L K   L  H                       W    W  CS +CG G++ R +TC   NG  S  ++  +   P +   C    C T   W +   S+C    C  G+    + C +        +KC   K P     C NT      W    W       +SC    R R+VYC+ + GN      CD   KP   + C
Sbjct:    6 IEAGYVETMVTADKSMVDAFPSKAELQSFIITIMGMVARIYRDKTIGNSINIVLVKIIIL------EIDLPELEITSNAASSLRSFCKWQTKMNKPSDEEPGHFDTAILLTRKDICRAAGKCDTLGLAELGTVCNPSRSCSIVEVTGLSSAFTIAHELAHVFNVPHDGDH--------NMCDEKSGNYNLMAPSLSFNTKPWMWSTCSRDAIRLFFDLGYGKCLEDK-------PDERQETQFDFELPGEKYSANDQCQLIFGSQSRLCPF----LDPCMRLWCVKNLGKRRGCQTHHMPWADGTPCGNHKWCIRGKCV-KNRRMKIVDGQWGNWAAFGACSRTCGGGIQFAKRECNNPEPENGGLYCQGARKRFRSCNSEECPPGSKDFRALQCAQLNNKPVRISGVAKTVNWLPKYQGVREEDRCKLYCQVESKRIHFKMSDKVIDGTPCQQFSSDVCVDGKCISAGCDRIVGSQAKYDVCRVCNGDNTTCKKHKGTY--RKIA-YGYNPVYKIPSGSTNVVIIEYGSRDA-------DNFLALKQVGPTARYLINGGSVVSLGERTYQIEGASIYYSGSDKAEEMIKITGKTQEDLLLEVLSVGKLTPPNVHYSLNVPFIGPHKFKWIIKRWT-------PCNRLCQGRRRRKVRCARVSDKRLVKSSRCKHLPRPASPSEKCNTDCELRWRTERED--------KCSAHCGPGKQKQKSDCMRVTGNK-----WQLVNVKYC---KHLERPLAVVPCEGKCENTRWVYTRWSQCSRTCGSGIKTRRANCVDHKGDF-----------LPDTDCRPSDRLLLQQVCEAECPKWRAADWEQASNLCSASCGSGMQSRVVQCSVGS-----------VIHP---DSACP-RAAKPTGTQRCNQQPCPAWETRNWSGCSVSCGVGEKTRSVTC--RYNGTSISPTRCDRA-LRPSLTE------RCTQPPCPTQAFIYPETKWKAGPWSQCSQSCGDQGRRMRRVTCA---DSRGVAVAE--RLCDAPNRPATYERCNVKPCTSWKHGAWGLCSKSCGKGVQSRIVKCAYE-NWKIAKDSQCDPFKRPPEQRECELQKCEELALHVNKQATVLPTDPYRPLTPAHQPTWRTSAWGACSVTCGKGIRRRPVTCTR-NGRTS--NACVQDSRPADTEVCTNAACPT---WIMGSWSKC-SLTCGGGVQTRRIDCSSSL------TKCDHRKKPVESRRC-NTEACPATWREGPWSKC---SVSCGRGQRRRNVYCLPEGGN------CDLRVKPSEIQPC 1180

HSP 2 Score: 208.379 bits (529), Expect = 4.783e-54
Identity = 210/762 (27.56%), Postives = 310/762 (40.68%), Query Frame = 1 
Query: 2611 TVEENLCFAVDLVDRPIEELNC-VGQCNPLLWSYGKWEECPIECGTTFRYRNFICK-------------------DNKGLEWQKEWCERHLGLPDNKE-TCLSFNNCRNLT-----RWVTSPWSRCSNSCESELQKRMVYCFRSEKSDEILDEKFLKIHEQISDAFCDIHSPKPITERPCSLNSCYFWIXXXXXXXXXXXXLGFRIQSHECKKKFNK-NHEMITVDDKFCLKQNLVKPLDVRMRCFLKKCAIESFWIEMEWSKCSVSCGEGLQYRSLKCGYENENKTLTTWDNNEMCKNKMVPVSIQICKVTPCPKWIYSEWSECEGTCEYGSQHRTVLCTDPISEQILPDSKCDIKNKFPNFQKCLLSKLCGHWIVGKWSQCSASCGLGVKTRTITCNYSNGSKSIDHSVC-KSVAPFEEIHCQVKPCSTNAFWWLVKPSECYEYNCQPGIMYAHVRCVNRKFQVLYDSKCS-RIKHPSYYVGCLNTTCRRYFWTAESWDNIPCPDISCTMKIRNRDVYCVDDYGNIQKDAMCDQSDKPDTWRLCPSPQNCSNIPRSCKELKSRQSVSKDGEYSLAIDLNWAYFIYCADMNTEEPKEYLTLRELNYARTSKYVSTDVSSCIYEEEMEFNQKCPT---------CKINENLWS-ITYYNKIRINLSDLSIDVMDDRFSATNGQSFIPFGTAKDCAGSTSCPKGHFKINLRGTGFSVSMETRWNEVYPKYGYRILRKQTSQIVKGWCGGHCSGCSPLKKFFVE 4779
             V E LC   D  +RP     C V  C    W +G W  C   CG   + R   C                    + +  E QK  CE  L L  NK+ T L  +  R LT      W TS W  CS +C   +++R V C R+ ++                     +   +P     C+  +C  WI     KCS  CG G + +  +C     K +H                KP++ R RC  + C   + W E  WSKCSVSCG G + R++ C  E  N           C  ++ P  IQ C    CP+W    WSEC  TC  G   R V C+          ++C    K    + C L   C  W+  +W +CS +CG+G + R++ C+         H  C K   P     C + PC+T   W     S+C    C  G     V C ++       S C  R K  S  V   +  C +  W   +W        +C + I +R+V C+    ++   A CD + +P   R+C   Q     PR+C+E++    +  DGE+ L +       IYC  M T++PKEY++L         K  S D  + +Y +++    +CP+         C   + + S  +Y+ K+RI++  + I   D +F++T G    P+ TA DC     CP+G F INL GTG  +S + RW      +   I R    + V   CGG C  CSP     ++
Sbjct:  925 AVAERLC---DAPNRPATYERCNVKPCTS--WKHGAWGLCSKSCGKGVQSRIVKCAYENWKIAKDSQCDPFKRPPEQRECELQK--CE-ELALHVNKQATVLPTDPYRPLTPAHQPTWRTSAWGACSVTCGKGIRRRPVTCTRNGRTSNAC-----------------VQDSRPADTEVCTNAACPTWIMGSWSKCSLTCGGGVQTRRIDCSSSLTKCDHRK--------------KPVESR-RCNTEACP--ATWREGPWSKCSVSCGRGQRRRNVYCLPEGGN-----------CDLRVKPSEIQPCAKKACPEWTVGRWSECSVTCGEGVVRRVVTCS-------AGGNRCQDDTKPEVVKLCELPD-CPSWLSQEWGECSVTCGVGRRLRSVVCSI--------HGKCDKQRQPSSSTLCNMGPCAT---WQTGTWSQC-SVTCGKGTQVRTVTCSDKD-----TSACDLRTKPQSSTVCGTSQECPK--WIIGNWSQC---SRTCGIGITSREVQCILGNNSLPY-ASCDSNSRPVIRRVC---QLIECTPRTCREIQLTSGLQADGEHVLQVQGK-LLKIYCHGMTTDDPKEYISL---------KTGSKDNFAEVYTKKLLDPNQCPSNGKHVDSCACYSQDYIDSGSSYFTKLRIDIVKMKIIPDDFQFASTRGLKPPPYATAGDCYSRKRCPQGRFSINLEGTGIELSPDVRWRSTGRSFTQLIYRYPEGKRVIAKCGGRCGMCSPATGIGLQ 1589
[Close]
BLAST of A disintegrin and metalloproteinase with thrombospondin motifs vs. Ensembl Nematostella
Match: EDO42270 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S1V9])

HSP 1 Score: 216.853 bits (551), Expect = 1.372e-60
Identity = 150/506 (29.64%), Postives = 223/506 (44.07%), Query Frame = 1 
Query:  598 FRQYILSNVAIATKLLHDPTIKASITXXXXXXXXXXEDYERNNDLHDWSLLSQDRVVSR-FCHWVRQKKQLWNYS------WDSAILIN------DGVFSSNAIGIAHLRSMCN-DNNCLAVVDRGFGTGFIIAHELAHQMNARHDFDNAEACSFFEKQYDNKTKYNTIMSTSLFFEYYP------FIWSVCSQNVINSFLKSKYSFCLKQRNRHRNLYPHEQINEFFQKYSTGVDYDLNEQCSFAFGEKSEFCETDQNSRKKCSVLYCRLKRYPICLRADAIIADGTECDVNQHCINGKCLYKNITIAPIDGGWSEYSEWSNCSRPCNGGVQFSYRTCDNPVPADGGRFCTGTKERIRSCNIEECSSFS-DPREESCGKYNLKP-------YIPTNDEEFPCNLVCITTNHSLKYDISLT----DGTPCSPFRSDICVKGTCYKTGCDRIVGSKKAIDNCNICAGQNDTCFKKESFFDGSKVAKVRMIRAFRIPPNVYNLFIKKV 2019
              +Y+L+ + + + +  DP++  SI I+V+ I+ L    E         +    R   R FC W    + +  YS      +D+A+L+       D     + +GI ++  MC+    C    D G    F IAHELAH     HD D               T Y+  +   +   + P        WS CS + +  FL+SK S CL    RH    P     +       GV Y  ++QC   +G +++ C+      + C  L+C ++  P+C       A GTEC   + C+ G C+   +    +DG W E+S W++CSR C  GV    R CDNP P +GG +C G K R R CN + C   S D RE  CGK+N          +IP   +  PC L C   N S ++   L     DGTPC+    DIC+ G C   GCD  +GS    D C +C G    C+  E  F+  ++A    + A  IP    N+ +++V
Sbjct:   10 IEEYVLTVMNMVSSMYRDPSLGTSIKIEVLKIIYLHATPE------GLRITPNGRKTLRSFCDWQNSLQWMTGYSAKHHWDYDAAVLMTRKDICADQNEPCSTVGIGYMYGMCDTKRRCSVSEDSGLNVAFTIAHELAHNFGVFHDGDGNRC-----------TDYSGYIPHLMSERWEPDNIHGSMKWSKCSIDSLQEFLRSKDSSCLY---RHALEKPIALPTDL-----AGVTYSADDQCRLQYGNRAKHCDKMSECDRMCQNLWCAIRGEPLCRTKRLPPARGTECGEGKWCMYGSCVNNTMIPVKLDGDWGEWSRWTDCSRTCGSGVTTMERKCDNPKPINGGHYCIGEKRRYRICNDKPCPEGSRDFREVQCGKFNNTKFKGKKYHWIPAISDGQPCALFCKPANQSWRFSAKLADAVVDGTPCAVGSRDICIGGKCQAVGCDHKLGSDAREDMCGVCKGNGTACYTVEGSFN--QLAGKGYVEAALIPKGARNIRVREV 488
[Close]
BLAST of A disintegrin and metalloproteinase with thrombospondin motifs vs. Ensembl Nematostella
Match: EDO32516 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SUT8])

HSP 1 Score: 220.32 bits (560), Expect = 3.169e-59
Identity = 205/843 (24.32%), Postives = 336/843 (39.86%), Query Frame = 1 
Query:  367 PHKIYF-TALNLNKPLFSCKLLKNNGYRNIPQESHFSRVFQRMKRETYPVVDSE---------IVEPNIIELLIVVTSNFVKRFKKDFRQYILSNVAIATKLLHDPTIKASITXXXXXXXXXXEDYERNNDLHDWSLLSQDRVVSRFCHW---VRQKKQLWNYSWDSAILIN-----DGVFSS-NAIGIAHLRSMCNDN-NCLAVVDRGFGTGFIIAHELAHQMNARHDFDNAEACSFFEKQYDNKTKYNTIMSTSLFFEYYPFIWSVCSQNVINSFLKSKYSFCLKQRNRHRNLYPHEQINEFFQKYSTGVDYDLNEQCSFAFGEKSEFCETDQNSRKKCSVLYCRLKRYPICLRADAIIADGTECDVNQHCINGKCLYKNITIAPIDGGWSEYSEWSNCSRPCNGGVQFSYRTCDNPVPADGGRFCTGTKERIRSCNIEECSSFS-DPREESCGKYNLK-------PYIPTNDEEFPCNLVCITTNH-----SLKYDISLTDGTPCSPFRSDICVKGTCYKTGCDRIVGSKKAIDNCNICAGQNDTCFKKESFFDGSKVAKVRMIRAFRIPPNVYNLFIKKVSQRMTPFTDEVYDDFELLLVVNRRTVIRRSETIEPLAGGQLRYSGSKNKVETISIKGKLNVGISIVIKVENTKTTLNLPFISYHYFVKDI-----FVWKYLEVITHPCKDQCG-GFIEISPACFKKRDNQRYVDHYCSKATKPEPKIIKCGA-ICGYRWQRATEHYINSTVNKSCPIRCGTGKVKIPFVCQKINNQDDNNSLWETVEENLCFAVDLVDRPIEELNCVGQCNPLLWSYGKWEECPIECGTTFRYRNFICK 2775
            PH +Y  +A++++ P          G +    ++H     ++ KRE Y  +  E         +     +E+L+V      +       +Y+L+ + +   +  D +I  +I I VV I++L  D    +  H          +  FC W   V  +        D A+L+       G+      +G+A +  MC    +C    D G    + IAHE+ H     HD D  +      K+ DN T Y  +MS  L        WS CS+  +  FL   + +CL       N  P +           G  YD + QC   +G  S  C    +    C  L+C++ +   C       ADGT C  ++ C  G+C+ + +    +DGGW ++S WS CSR C GGV  S R CDNP P + G++C G   + R CN++EC+  S D RE  C ++N +        + P      PC L C          S K+   + DGT C P + D+C+ G C   GCD ++ S    D C +C G   +C   +S F+  +   +  +    IP    ++ + +V+                L   N    I+ S   +  AG  +RY+   NK ET S  G     + I++  +     +   +      V++      F W+Y + +  PC   CG G       C+++  +    + YC+  T+P+ +   C    C   W R      + + ++   +R          +C +    D+  +L    E+  C       RP+    C  +  P  W  G W +C   CG   + R   CK
Sbjct:   26 PHLVYRRSAMSVSGP----------GDQRPGCDTHEKISMEKRKREPYLELIRETGHERQRRSVSTERNVEVLVVADRTMHEFHGAALEEYLLTVMNMVNNIYRDQSIGNAINIVVVRIIILKRDLPDLDIGH-----HAGNTIESFCAWASRVNPRSDTHPNHHDVAVLVTRKDICKGIDEPCGTLGLAQVNGMCTSTKSCNVNEDSGLSVAYTIAHEIGHNFGMLHDGDENDC-----KRNDN-TPY--LMSALLQTTGKQQYWSECSRGYLRRFLNKGWGWCL-------NDVPSQHPRFRATVALPGTVYDADHQCRLQYGSNSSQCTGMSDP---CGTLWCKVGK--ACQSKLEQAADGTYCGKDKWCFQGRCIKQGVIPKSVDGGWGQWSNWSECSRSCGGGVSSSERHCDNPRPMNNGKYCIGKWRKYRLCNVKECAVGSIDFRERQCAEFNTRVIRNRKWHWKPKILRSRPCELHCSPRGAYGRFFSKKFGDHVVDGTKCFPSKRDVCIAGKCEYVGCDNVLHSNAREDRCGVCRGDGSSCETVKSTFN--QTTGIGYVETKIIPQGARHIKVAEVAGAPNYLALRSSSGKYYL---NGHWYIQWSGEYQ-AAGTTVRYTRKHNK-ETFSADGPTTSDLHIMLLFQTRNPGIEFEYTIPKKTVEEFRGSLSFKWRYTDWM--PCSATCGVGTTRSEVECYEESSDSPIDEKYCNGTTRPDDRQKTCNENPCPATWYRGPWQTCSQSCDRGVSVR--------SVLCVRSIKNDEQVAL----EDKECAR----PRPLSVRACYKRPCPPPWVSGNWTKCSARCGRGIQRRAVTCK 808

HSP 2 Score: 70.4774 bits (171), Expect = 4.733e-12
Identity = 42/151 (27.81%), Postives = 68/151 (45.03%), Query Frame = 1 
Query: 3295 WIEMEWSKCSVSCGEGLQYRSLKCGYENENKTLTTWDNNEMCKNKMVPVSIQ-ICKVTPCPK-WIYSEWSECEGTCEYGSQHRTVLCTDPI--SEQILPDSKCDIKNKFPNFQKCLLSKLCGHWIVGKWSQCSASCGLGVKTRTITCNYSN 3735
            W   +W  CS +CG G     ++C  E+ +  +    + + C     P   Q  C   PCP  W    W  C  +C+ G   R+VLC   I   EQ+  + K   + +  + + C        W+ G W++CSA CG G++ R +TC  ++
Sbjct:  665 WRYTDWMPCSATCGVGTTRSEVECYEESSDSPI----DEKYCNGTTRPDDRQKTCNENPCPATWYRGPWQTCSQSCDRGVSVRSVLCVRSIKNDEQVALEDKECARPRPLSVRACYKRPCPPPWVSGNWTKCSARCGRGIQRRAVTCKGAD 811

HSP 3 Score: 52.373 bits (124), Expect = 1.782e-6
Identity = 32/117 (27.35%), Postives = 49/117 (41.88%), Query Frame = 1 
Query: 3475 KWIYSEWSECEGTCEYGSQHRTVLCTDPISEQILPDSKCDIKNKFPNFQKCLLSKLC-GHWIVGKWSQCSASCGLGVKTRTITCNYS---NGSKSIDHSVCKSVAPFEEIHCQVKPC 3813
            KW Y++W  C  TC  G+    V C +  S+  + +  C+   +  + QK      C   W  G W  CS SC  GV  R++ C  S   +   +++   C    P     C  +PC
Sbjct:  664 KWRYTDWMPCSATCGVGTTRSEVECYEESSDSPIDEKYCNGTTRPDDRQKTCNENPCPATWYRGPWQTCSQSCDRGVSVRSVLCVRSIKNDEQVALEDKECARPRPLSVRACYKRPC 780

HSP 4 Score: 50.8322 bits (120), Expect = 4.928e-6
Identity = 48/176 (27.27%), Postives = 66/176 (37.50%), Query Frame = 1 
Query: 3652 WIVGKWSQCSASCGLGVKTRTITCNYSNGSKSIDHSVCKSVAPFEEIH--CQVKPCSTNAFWWLVKPSECYEYNCQPGIMYAHVRCV----NRKFQVLYDSKCSRIKHPSYYVGCLNTTCRRYFWTAESWDNIPCPDISCTMKIRNRDVYCVDDYGNIQKDAMCDQSDKPDTWRLC 4161
            W    W  CSA+CG+G     + C   +    ID   C      ++    C   PC      W   P +    +C  G+    V CV    N +   L D +C+R + P     C    C    W + +W         C   I+ R V C      IQK   CD S +P +WRLC
Sbjct:  665 WRYTDWMPCSATCGVGTTRSEVECYEESSDSPIDEKYCNGTTRPDDRQKTCNENPCPAT---WYRGPWQTCSQSCDRGVSVRSVLCVRSIKNDEQVALEDKECARPR-PLSVRACYKRPCPPP-WVSGNWTKC---SARCGRGIQRRAVTC-KGADIIQKP--CDISSRPVSWRLC 829
[Close]
BLAST of A disintegrin and metalloproteinase with thrombospondin motifs vs. Ensembl Nematostella
Match: EDO47184 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RMZ8])

HSP 1 Score: 179.489 bits (454), Expect = 1.286e-45
Identity = 155/551 (28.13%), Postives = 236/551 (42.83%), Query Frame = 1 
Query:  862 NAIGIAHLRSMCNDNNCLAV-VDRGFGTGFIIAHELAHQMNARHDFDNAEACSFFEKQYDNKTKYNTIMSTSLFFEYYPFIWSVCSQNVINSFLKSKYSFCLKQRNRHRNLYPHEQINEFFQKYSTGVDYDLNEQCSFAFGEKSEFCETDQNSRKKCSVLYCRL-KRYPICLRADAIIADGTECDVNQHCINGKCLYKNI-TIAPIDGGWSEYSE-WSNCSRPCNGGVQFSYRTCDNPVPADGGRFCTGTKERIRSCNIEECS-SFSDPREESCGKYNLKPYIPTNDE----EFP----CNLVCITTNHSLKYDIS-LTDGTPCSPFRSDICVKGTCYKTGCDRIVGSKKAIDNCNICAGQNDTCFKKESFFDGSKVAKVRMIRAFRIPPNVYNLFIKKVSQRMTPFTDEVYDDFELLLVVNRRTVIRRSETIEPLAGGQLRYSGSKNKVETISIKGKLNVGISI---VIKVENTKTTLNLPFISYHYFV---KDIFVWKYLEVITHPCKDQCGGFIEISPA-CFKKRDNQRYVDHYCSKATKPEPKIIKC 2451
            + +G+A  R MC+  +  +V  D G   G  +AHE  H M   HD  +   C+  E           +MST    +   F WS CS+N +  FL S  S CL  +   R+L     ++      + G  YD ++QC  A+G++++FC   +   + C  L+C +      C  A     DGT C   + C  G C+         +DGGWSE+SE +S CSR C GGVQ+  R C+ P P +GG+ C G     + CN++ CS S  D R   C + + + +   ND+    EF     C L C   N  L +    + DGT CS    D C+ G C + GCD ++ S+  ID C +C G   +C       + +  A+ +        P+   L +  +S       +  YD       V+RR  + + +      G  ++ S S  + E+  IK  LN  +SI   +++   T      P  +    +    D F W    V    C   CGG  E S A C +  D     +  C    KP  + + C
Sbjct:  317 DTLGLARTRGMCSFPSSASVNQDNGLMLGMTLAHETGHSMGINHDGGD---CADGE----------NVMSTFAPGKPAAFSWSSCSRNYLKQFLASDDSKCLDDQPTRRSLISTAALD------NPGRLYDKDQQCQLAYGQEAKFCSGAKFLDQVCVKLWCEVPAGSGQCKTAQVPATDGTSCGEGKWCKRGHCVASTSEGDGAMDGGWSEWSENYSRCSRSCGGGVQYRERRCNKPQPKNGGKHCAGADREYKLCNVDSCSISEVDFRNYQCQEKDSQMF---NDQYYNWEFKPSTLCILGCFIKNTGLGFAFGNVVDGTDCSEGSPDKCIMGQCKRVGCDGVIDSRAVIDRCGVCDGDGSSCTGVTDTANNTSSAQKK-----DALPHGGGLLVTAISV----LKNLGYD-------VDRRGHVAKPDDDRSNTG--IKSSRSDLRGESFLIKESLNTMLSIRFLILRNHPTPPPPAYPGYAPDILLMNGDDTFYWA---VEKTGCSVSCGGGAERSYAQCRRSDDGSPVAERKCDVTKKPPRQEMHC 824

HSP 2 Score: 58.9214 bits (141), Expect = 1.827e-8
Identity = 39/150 (26.00%), Postives = 63/150 (42.00%), Query Frame = 1 
Query: 3286 ESFWIEMEWSKCSVSCGEGLQYRSLKCGYENENKTLTTWDNNEMCK-NKMVPVSIQICKVTPCPK-WIYSEWSECEGTCEYGSQHRTVLCTDPISEQIL--PDSKCDIKNKFPNFQKCLLSKLCGHWIVGKWSQCSASCGLGVKTRTITC 3723
            ++F+  +E + CSVSCG G +    +C   ++   +        C   K  P     C   PCP  W    W +C  TC  G++ R V C    ++ +    D +  +  + P  + C        W+   +  CS  CG G +TRT+ C
Sbjct:  771 DTFYWAVEKTGCSVSCGGGAERSYAQCRRSDDGSPVA----ERKCDVTKKPPRQEMHCNRQPCPPVWKAEGWEDCTRTCNGGNRTRQVKCMQVAADGVEYDVDQRLCLDPRPPTVEACNTVPCLPEWVAQPFGPCSTVCGRGEQTRTVKC 916

HSP 3 Score: 51.9878 bits (123), Expect = 2.162e-6
Identity = 48/190 (25.26%), Postives = 77/190 (40.53%), Query Frame = 1 
Query: 2518 SCPIRCGTGKVKIPFVCQKINNQDDNNSLWETVEENLCFAVDLVDRPI-EELNCVGQCNPLLWSYGKWEECPIECGTTFRYRNFICKD--NKGLEWQKEWCERHLGLPDNKETCLSFNNCRNLTRWVTSPWSRCSNSCESELQKRMVYCFRSEKSDEILDEKFLKIHEQISDA--------FCDIHSPKP 3054
             C + CG G  +    C++    DD +     V E  C   D+  +P  +E++C  Q  P +W    WE+C   C    R R   C      G+E+     ++ L L     T  + N    L  WV  P+  CS  C    Q R V C +++     ++   L++ E   D         +C++H+P P
Sbjct:  781 GCSVSCGGGAERSYAQCRR---SDDGSP----VAERKC---DVTKKPPRQEMHCNRQPCPPVWKAEGWEDCTRTCNGGNRTRQVKCMQVAADGVEYD---VDQRLCLDPRPPTVEACNTVPCLPEWVAQPFGPCSTVCGRGEQTRTVKCMKAD-----VNSNLLEVPEAQCDGMMKPPLKEYCNVHNPCP 952
[Close]
BLAST of A disintegrin and metalloproteinase with thrombospondin motifs vs. Ensembl Nematostella
Match: EDO35202 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SM44])

HSP 1 Score: 165.236 bits (417), Expect = 3.811e-41
Identity = 177/665 (26.62%), Postives = 268/665 (40.30%), Query Frame = 1 
Query:  850 VFSSNAIGIAHLRSMCNDNNCLAVVDRGFGTGFIIAHELAHQMNARHDFDNAEACSFFEKQYDNKTKYNTIMSTSLFFEYYPFIWSVCSQNVINSFLKSKYSFCLKQRNRHRNLYPHEQINEF--FQKYSTGVDYDLNEQCSFAFGEKSEFCETDQNSRKKCSVLYCRLKRYPICLRADAIIADGTECDVNQHCINGKCLYKNITIAPIDGGWSEYS-EWSNCSRPCNGGVQFSYRTCDNPVPADGGRFCTG-TKERIRSCNIEECSSFSDP-REESCGKYNLKPYIPTNDEE----FPCNLVCITTNHSLKYDIS-LTDGTPCSPFRS--DICVKGTCYKTGCDRIVGSKKAIDNCNICAGQNDTCFKKESFFDG--SKVAKVRMIRAFRIPPNVYNLFIKKVSQRMTPFTDEVYDDFELLLVVNRRTVIRRSETIEPLAGGQLRYSGSKNKVE-TISIKGKLN--VGISIVIKVENTKTTLNLPFISYHYFVKDIFV-WKYLEVITHPCKDQCG-GFIEISPACFKKRDNQRYVDHYCSKATKPEPKIIKCGAICGYRWQRATEHYINSTVNKSCPIRCGTGKVKIPFVCQKINNQDDNNSLWETVEENLCFAVDLVDRPIEELNCVGQCN----PLLWSYGKWEECPIECGTTFRYRNFICK 2775
            V  S   G+A   S C         + G     I+AHE+AH +   HD  ++        QY        IM TS+      + +S CS+  + S L       L          P + ++    +Q    G  YD  +QC   +    + C         C +LYC       CL  +A   DGT C V + CI G+C+  +   +P+DGGWS++S E+S CS  C GGVQ+  RTC NP P  GG  C G ++   + CN + C S +D  R+  C   N K   P   ++    + C+L+CI    SL +    + DGT C    S  D+C++G C + GCD ++GS + +D C +C G + TC      +     +       + F +P    N+ ++K +            D     ++N  T    S T+E  AG ++ Y    +  + TI I G  N  +G+ +V  + + K       I  +  V    V WK        C   CG G  E   AC +K D++ YV       +KP        A C   W         +T    C   CG G      +C++       +  +ET+ +  C       +P   LN   +CN    P  W   +W  C   C    + R   CK
Sbjct:  274 VTRSVTGGLASAGSTCGSLGKALAGNSGIQASIIVAHEIAHTLGVGHDGASSRP-DCRNGQY--------IMGTSVSGGGKAYKFSPCSREKLQSILTGSSCSPLDDA-------PGKMVHSLTSWQGKHPGQIYDRTKQCQMTYNSDYKGCGPKIGD---CGLLYCSKNGGVTCLSMNAPPLDGTHCGVRKWCIAGECV--DDGSSPVDGGWSDWSAEYSTCSYSCGGGVQWKTRTCTNPKPLRGGADCVGPSRAHYKICNPQPCPSGTDTYRKHQCRAINFKAPEPRYSKDSTTGYECDLLCI--EGSLMHPRGKVGDGTRCFKDSSIKDVCIQGKCEQVGCDDVLGSGQRVDRCGVCNGDSSTCSVVTGTYSAHCPRWGPYPGCKMFDLPAGATNVHVEKTNADHNVLG---IKDASGSYLINLPTW---STTVE-AAGTKVIYKHEDSVYQDTIDIPGPTNEQLGLFMVSVIGSNKAVTWTYLIPGNSSVSSSDVEWK--TGAWSACSKACGTGSQERDVACVRK-DDKTYVRESLCAGSKPAANQECETAKCVSSWY--------TTEWSPCSATCGKGTQSRSVICRR--ETFTGSKQYETLPDASCTG----SKPTVTLN--QECNKVDCPPEWMPTEWSACTKTCAGGRQSRTLSCK 889

HSP 2 Score: 60.4622 bits (145), Expect = 6.107e-9
Identity = 43/121 (35.54%), Postives = 57/121 (47.11%), Query Frame = 1 
Query: 3205 DDKFCLKQNL---VKPLDVRMRCFLKKCAIESFWIEMEWSKCSVSCGEGLQYRSLKCGYE--NENKTLTTWDNNEMCKNKMVPVSIQICKVTPC-PKWIYSEWSECEGTCEYGSQHRTVLC 3549
            DDK  ++++L    KP      C   KC   S W   EWS CS +CG+G Q RS+ C  E    +K   T  +     +K      Q C    C P+W+ +EWS C  TC  G Q RT+ C
Sbjct:  771 DDKTYVRESLCAGSKPA-ANQECETAKCV--SSWYTTEWSPCSATCGKGTQSRSVICRRETFTGSKQYETLPDASCTGSKPTVTLNQECNKVDCPPEWMPTEWSACTKTCAGGRQSRTLSC 888

HSP 3 Score: 55.0694 bits (131), Expect = 3.173e-7
Identity = 45/177 (25.42%), Postives = 69/177 (38.98%), Query Frame = 1 
Query: 3475 KWIYSEWSECEGTCEYGSQHRTVLCTDPISEQILPDSKCDIKNKFPNFQKCLLSKLCGHWIVGKWSQCSASCGLGVKTRTITCNYS--NGSK---SIDHSVCKSVAPFEEIHCQVKPCSTNAFWWLVKPSECYEYNCQPGIMYAHVRC----VNRKFQVLYDSKCSRIKHPSYYVGC 3978
            +W    WS C   C  GSQ R V C     +  + +S C       N Q+C  +K    W   +WS CSA+CG G ++R++ C      GSK   ++  + C    P   ++ +         W   + S C +  C  G     + C    +N  +  + D  C     PS    C
Sbjct:  743 EWKTGAWSACSKACGTGSQERDVACVRKDDKTYVRESLCAGSKPAAN-QECETAKCVSSWYTTEWSPCSATCGKGTQSRSVICRRETFTGSKQYETLPDASCTGSKPTVTLNQECNKVDCPPEWMPTEWSACTK-TCAGGRQSRTLSCKLKDLNGAYHEVADYHCHNAIKPSRQQAC 917

HSP 4 Score: 50.8322 bits (120), Expect = 4.871e-6
Identity = 52/193 (26.94%), Postives = 82/193 (42.49%), Query Frame = 1 
Query: 2884 WVTSPWSRCSNSCESELQKRMVYCFRSEKSDEILDEKFLKIHEQISDAFCDIHSPKPITERPCSLNSCYF-WIXXXXXXXXXXXXLGFRIQSHECKKK-FNKNHEMITVDDKFCLKQNLVKPLDVRMRCFLKKCAIESFWIEMEWSKCSVSCGEGLQYRSLKCGYENENKTLTTWDNNEMCKNKMVPVSIQIC 3456
            W T  WS CS +C +  Q+R V C R +      D+ +++      ++ C     KP   + C    C   W  ++   CSA CG G + +S  C+++ F  + +  T+ D  C        L+    C    C  E  W+  EWS C+ +C  G Q R+L C  ++ N       +   C N + P   Q C
Sbjct:  744 WKTGAWSACSKACGTGSQERDVACVRKD------DKTYVR------ESLCA--GSKPAANQECETAKCVSSWYTTEWSPCSATCGKGTQSRSVICRRETFTGSKQYETLPDASCTGSKPTVTLN--QECNKVDCPPE--WMPTEWSACTKTCAGGRQSRTLSCKLKDLNGAYHEVADYH-CHNAIKPSRQQAC 917
[Close]
BLAST of A disintegrin and metalloproteinase with thrombospondin motifs vs. Ensembl Medaka
Match: ADAMTS20 (A disintegrin and metalloproteinase with thrombospondin motifs 20 [Source:NCBI gene;Acc:101170674])

HSP 1 Score: 382.489 bits (981), Expect = 1.592e-108
Identity = 357/1395 (25.59%), Postives = 551/1395 (39.50%), Query Frame = 1 
Query:  412 FSCKLLKNNGYRNIPQESH-------FSRVFQRMKRETYPVVDSEIVEPNIIELLIVVTSNFVKRFKKDFRQYILSNVAIATKLLHDPTIKASITXXXXXXXXXXEDYERNNDLHDWSLLSQDRVVSRFCHWVRQKKQLWNYS----WDSAILIND-----GVFSSNAIGIAHLRSMCND-NNCLAVVDRGFGTGFIIAHELAHQMNARHDFDNAEACSFFEKQYDNKTKYNTIMSTSLFFEYYPFIWSVCSQNVINSFLKSKYSFCLKQRNRHRNLYPHEQINEFFQKYSTGVDYDLNEQCSFAFGEKSEFCETDQNSRKKCSVLYCRLKR--YPICLRADAIIADGTECDVNQHCINGKCLYKNITIAPIDGGWSEYSEWSNCSRPCNGGVQFSYRTCDNPVPADGGRFCTGTKERIRSCNIEECS-SFSDPREESCGKYNLKPY----IPTNDEEFP----------CNLVCITTNHSLKYDIS--LTDGTPCSPFRSDICVKGTCYKTGCDRIVGSKKAIDNCNICAGQNDTCFKKESFFDGSKVAKVRMIRAFRIPPNVYNLFIKKVSQRMTPFTDE--VYDDFELLLVVNRRTVIRRSETIEPLAGGQLRYSGSKNKVETISIKGKLNVGISI-VIKVEN-----TKTTLNLPFISYHYFVKDIFVW----KYLEVITHPCKDQCGGFIEISPACFKKRDNQRYVDHYCSKATKPEPKIIKCGAICGYRWQRATEHYINSTVNKSCPIRCGTGKVKIPFVCQKINNQDDNNSLWETVEENLCFAVDLVDRPIEELNCVGQCNPLLWSYGKWEECPIECGTTFRYRNFICKDNKGLEWQKEWCERHLGLPDNKETCLSFNNCRNL--TRWVTSPWSRCSNSCESELQKRMVYCFRSEKSDEILDEKFLKIHEQISDAFCDIHSPKPITERPCSLNSCYFWIXXXXXXXXXXXXLGFRIQSHECKKKFNKNHEMITVDDKFCLKQNLVKPLDVRMRCFLKKCA----------------IESFWIEMEWSKCSVSCGEGLQYR--------------------------------------------SLKCGYENENKTLTTWD-----NNEMCKNKMVPVSIQICKVTPCP-----------------------------------KWIYSEWSECEGTCEYGSQHRTVLCTDPISEQILPDSKCDIKNKFPNFQKCLLSKLCGHWIVGKWSQCSASCGLGVKTRTITCNYSNGSKSIDHSVCKSVAPFEEIHCQVKPCSTNAFWWLVKPSECYEYNCQPGIMYAHVRCVNRKFQVLYDSKCSRIKHPSYYVGCLNTTCRRYFWTAESWDNIPCPDISCTMKIRNRDVYC-VDDYGNIQKDAMCDQSDKP 4143
             +C + K+       QESH        SR  +R KR         +  P  +EL++   +   +   ++   YIL+ +++A  +  DP++   I I VV +V++  + E      D +       +  FC W +Q + +   S     D+A+LI            + +G+A L +MC+   +C    + G    F IAHEL H  N  HD  ++  C    ++   K +Y+ +M+ +L ++  P+ WS CS+  I  FL + Y  CL          P  +I E       G  Y+ N QC   FG  S+ C       K+C  L+C      +  C      +ADGT+C    +C +G C+ K + + P+ G W  +  +S CSR C GG + + R C  P P +GGRFC G + + RSCN E C     D REE C +++ K +    +  N    P          C L C      + Y +   + DGTPC P   DICV+G C + GCD ++ SK   D C +C G N +C      F+ ++     ++   RIP    N+ IK+VS    P  D      D +   ++N   V+   +    L G  + YSGS  KVE I+   ++   I + V+ V N      + + N+P   +    ++ F+W     +LE     C   C G       CF++ D+    D  C    +P      C A C  RW  A +          C  +CG G   +   C K +     +   E VE + C     + +P    +C G C    W Y  W +C   CG   R R   C +N G       C             +    C +L   +W  + WS C  +C   ++ R+V C   E+             E++S+ +CD+ S KP     C L  C  W     G C+  CG G+++++  C      N    TVDD+ C      +P D +  C +  C                 + + W    W+ CSVSCG+G Q R                                            S+ CG     + +   +     +   C N   P + Q C   PCP                                   +W    W  C  TCE G Q R V+C D        +S CD + K P   K   S  C  W  G W +C+  CG G +TR + C   NG   ID++      P +   C ++PC  +A W   +P +    +C  GI    + CV +    L ++ CS ++ P     C    C    W    W       ++C   ++NRDVYC +   G +++D +CD   +P
Sbjct:  213 LTCSIYKHRLNTIEQQESHETNSTGEHSRPGRRRKRF--------LSYPRYVELMVTADAKMAQHHGRNLEHYILTIMSVAA-VYKDPSVGNLINIMVVKLVIIHNEQEGPTVSFDAAT-----TLHNFCVW-QQNQNVQEDSDPSHHDTALLITREDICRAKHKCDTLGLAELGTMCDPYRSCSISEENGISASFTIAHELGHVFNMPHD--DSPMC----REAGMKHQYH-VMAPTLNYDTNPWSWSKCSRKYITEFLDTGYGECLLDE-------PVGRIYEL-PTLLPGQIYNANRQCELMFGPGSQICPY----MKQCKRLWCTSSEGDHKGCRTQHMPLADGTDCGHGMYCRHGMCVNKELDLQPVHGEWGPWGPYSACSRSCGGGTRSATRDCKKPEPRNGGRFCVGRRMKFRSCNTEPCPRGKKDFREEQCSQFDGKHFNINGLTPNVRWVPKYSGILMKDRCKLFCRVAGAMMYYQLKDRVIDGTPCGPDTYDICVQGLCRQAGCDHVLNSKARNDKCGVCGGDNSSCKTLAGTFNDAQYGYNTVV---RIPAGATNIDIKQVSYSGKPEDDSYLALSDSQSNFLLNGNFVVSMFKREITLKGTVIEYSGSDTKVERINCTDRIEEEIILQVLCVGNPHNPDVRYSFNIPIEEH----REQFLWDPSGSWLE-----CSRMCHGKKRRKAVCFRQSDHLEVSDQRCEHLPRPVAVTEPCNADCEVRWHVAGK--------SECSAKCGPGHRSLDIQCMKYSLLQRES---ERVEASACAE---IPKPHTRESCHGDCLLKSWQYSAWTQCSKTCGRGSRSRESYCMNNLGRRLVDRECSEFQR--------VVIETCNDLPCPQWTVNEWSECLVTCGKGMKHRLVTCMGGEE-------------EKLSEQYCDL-STKPAATESCQLPECASWQVGIWGACAVTCGHGYQMRAVRCVLGDYGN----TVDDREC--NAAARPRDSQ-ECEMPACPWISPVQSTPRPDNSAQLHTQWRYGSWTACSVSCGKGKQARYVTCINAQGAVADESYCAHLPRPPEFSTCFSPCGQWHAREWSTCSVTCGVGRATRQVVCSNYHHPVDQSFCDNDDKPATEQECTAGPCPSVYNRQRIYEQPYGYPQDPGHHPGHSSWNVPSADNQWRTGPWGACSSTCEGGFQRRVVVCQDGDGRS---NSYCDERIK-PAESKSCDSGPCPLWNYGVWGECTQPCGGGRRTRLVVCQRPNGETLIDYNCDMLDKPLDMEQCNLQPCPGSASWHR-QPWKPCSVSCGRGIKQREIACVYQNQTKLEEAHCSHLQRPRTQKACRARICP--TWKTSRWREC---SVTCGFGVQNRDVYCRLKGAGRVRED-LCDAGTRP 1507

HSP 2 Score: 137.502 bits (345), Expect = 6.313e-32
Identity = 122/496 (24.60%), Postives = 184/496 (37.10%), Query Frame = 1 
Query: 2701 WSYGKWEECPIECGTTFRYRNFICKDNKGLEWQKEWCERHLGLPDNKETCLSFNNCRNLTRWVTSPWSRCSNSCESELQKRMVYCFRSEKSDEILDEKFLKIHEQISDAFCDIHSPKPITERPCSLNSCYFWIXXXXXXXXXXXXLGFRIQSHECKKKFNKNHEMITVDDKFCLKQNLVKPLDVRMRCFLKKCAIESFWIEMEWSKCSVSCGEGLQYRSLKCGYENENKTLTTWDNNEMCKNKMVPVSIQICKVTPCPKWIYSEWSECEGTCEYGSQHRTVLCTDPISEQILPDSKCDIKNKFPNFQKCLLSKLCG--HWIVGKWSQCSASCGLGVKTRTITCNYSNGSKSIDHSVCKSVAPFEEIHCQVKPCSTNAFWWLVKPSECYEYNCQPGIMYAHVRCVNRKFQVLYDSKCSRIKHPSYYVGCLNTTCRRYFWTAESWDNIPCPDISCTMKIRNRDVYCVDDYGNIQKDAMCDQSDKPDTWRLCPSPQNCS 4182
            W YG W  C + CG   + R   C + +G    + +C  HL  P    TC  F+ C    +W    WS CS +C      R V C                 H  +  +FCD +  KP TE+ C+                             C   +N+       +  +   Q+   P            + ++ W    W  CS +C  G Q R + C  + + ++      N  C  ++ P   + C   PCP W Y  W EC   C  G + R V+C  P  E ++ D  CD+ +K  + ++C L    G   W    W  CS SCG G+K R I C Y N +K  +        P  +  C+ + C T   W   +  EC    C  G+    V C  +    + +  C     P +   C    C  Y W    WD     ++SC    R+R V+C        ++  C+ S +P      PS Q+C+
Sbjct: 1151 WRYGSWTACSVSCGKGKQARYVTCINAQGAVADESYCA-HLPRPPEFSTC--FSPC---GQWHAREWSTCSVTCGVGRATRQVVCS--------------NYHHPVDQSFCD-NDDKPATEQECTAGP--------------------------CPSVYNRQR---IYEQPYGYPQD---PGHHPGHSSWNVPSADNQWRTGPWGACSSTCEGGFQRRVVVC-QDGDGRS------NSYCDERIKPAESKSCDSGPCPLWNYGVWGECTQPCGGGRRTRLVVCQRPNGETLI-DYNCDMLDKPLDMEQCNLQPCPGSASWHRQPWKPCSVSCGRGIKQREIACVYQNQTKLEEAHCSHLQRPRTQKACRARICPT---WKTSRWREC-SVTCGFGVQNRDVYCRLKGAGRVREDLCDAGTRPLFLQPCHTAECTHYTWVTGEWDKC---NVSCGDGTRSRKVWCAGPEMTPAQNDYCEPSSRP------PSVQSCT 1572

HSP 3 Score: 129.028 bits (323), Expect = 2.390e-29
Identity = 135/492 (27.44%), Postives = 206/492 (41.87%), Query Frame = 1 
Query: 2821 LGLPDNKETCLSFN----NCRNLTRWVTS-PWSRCSNSCESELQKRMVYCFRSEKSDEILDEKFLKIHEQISDAFCDIHSPKPIT-ERPCSLNSCYFWIXXXXXXXXXXXXLGFRIQSHECKKKFNKNHEMITVDDKFCLKQNLVKPLDVRMRCFLKKCAIESFWIEMEWSKCSVSCGEGLQYRSLKCGYENENKTLTTWDNNEMCKNKMVPVSIQICKVTPCPKWIYSEWSECEGTCEYGSQHRTVLCTDPISEQILPDSKCDIKNKFPNFQKCLLSKLCGHWIVGKWSQCSASCGLGVKTRTITCNYSNGSKSIDHSVCKSVA-PFEEIHCQVKPC----------------STNAFWWLVKPSECYEYNCQPGIMYAHVRCVNRKFQVLYDSKCSRIKHPSYYVGCLNTTCRRYFWTAESWDNIPCPDISCTMKIRNRDVYCVDDYGNIQKDAMCDQSDKPDTWRLCPSPQNCSNIPRSCKELKSRQSV 4227
            +G P N +   SFN      R    W  S  W  CS  C  + ++R   CFR  +SD          H ++SD  C+ H P+P+    PC+ +    W  +   +CSAKCG G R    +C K      E   V+   C +  + KP   R  C    C ++S W    W++CS +CG G + R   C   N  + L   + +E  +     V I+ C   PCP+W  +EWSEC  TC  G +HR V C     E+ L +  CD+  K    + C L + C  W VG W  C+ +CG G + R + C   +   ++D   C + A P +   C++  C                  +  W     + C   +C  G    +V C+N +  V  +S C+ +  P  +  C +   +   W A  W       ++C +    R V C  +Y +    + CD  DKP T       Q C+  P  C  + +RQ +
Sbjct:  819 VGNPHNPDVRYSFNIPIEEHREQFLWDPSGSWLECSRMCHGK-KRRKAVCFR--QSD----------HLEVSDQRCE-HLPRPVAVTEPCNADCEVRWHVAGKSECSAKCGPGHRSLDIQCMKYSLLQRESERVEASACAE--IPKP-HTRESCH-GDCLLKS-WQYSAWTQCSKTCGRGSRSRESYC-MNNLGRRLVDRECSEFQR-----VVIETCNDLPCPQWTVNEWSECLVTCGKGMKHRLVTCMGG-EEEKLSEQYCDLSTKPAATESCQLPE-CASWQVGIWGACAVTCGHGYQMRAVRCVLGDYGNTVDDRECNAAARPRDSQECEMPACPWISPVQSTPRPDNSAQLHTQWRYGSWTAC-SVSCGKGKQARYVTCINAQGAVADESYCAHLPRPPEFSTCFSPCGQ---WHAREWSTC---SVTCGVGRATRQVVC-SNYHHPVDQSFCDNDDKPAT------EQECTAGP--CPSVYNRQRI 1267

HSP 4 Score: 127.872 bits (320), Expect = 5.426e-29
Identity = 117/434 (26.96%), Postives = 175/434 (40.32%), Query Frame = 1 
Query: 2518 SCPIRCGTGKVKIPFVCQKINNQDDNNSLWETVEENLCFAVDLVDRPIEELNCVGQCNPLLWSYGKWEECPIECGTTFRYRNFICK-----------DNKGLEWQKEWC---------------ERHLGLPDN---KETCLSFNNCRNLTRWVTSPWSRCSNSCESELQKRMVYCFRSE-KSDEILDEKFLKIHEQISDAFCDIHSPKPITERPCSLNSCYFWIXXXXXXXXXXXXLGFRIQSHECKKKFNKNHEMITVDDKFCLKQNLVKPLDVRMRCFLKKCAIESFWIEMEWSKCSVSCGEGLQYRSLKCGYENENKTLTTWDNNEMCKNKMVPVSIQICKVTPCPKWIYSEWSECEGTCEYGSQHRTVLCTDPISEQILPDSKCDIKNKFPNFQKCLLSKLCGH--WIVGKWSQCSASCGLGVKTRTITC 3723
            +C + CG GK      C  IN Q          +E+ C  +    RP E   C   C    W   +W  C + CG     R  +C            DN      ++ C               E+  G P +        S+N      +W T PW  CS++CE   Q+R+V C   + +S+   DE+                  KP   + C    C  W     G+C+  CG G R +   C++   +     T+ D  C    L KPLD+  +C L+ C   + W    W  CSVSCG G++ R + C Y+N+ K          C +   P + + C+   CP W  S W EC  TC +G Q+R V C    + ++  D  CD   +    Q C  ++ C H  W+ G+W +C+ SCG G ++R + C
Sbjct: 1158 ACSVSCGKGKQARYVTC--INAQG------AVADESYCAHLP---RPPEFSTCFSPCG--QWHAREWSTCSVTCGVGRATRQVVCSNYHHPVDQSFCDNDDKPATEQECTAGPCPSVYNRQRIYEQPYGYPQDPGHHPGHSSWNVPSADNQWRTGPWGACSSTCEGGFQRRVVVCQDGDGRSNSYCDERI-----------------KPAESKSCDSGPCPLWNYGVWGECTQPCGGGRRTRLVVCQRPNGE-----TLIDYNC--DMLDKPLDME-QCNLQPCPGSASWHRQPWKPCSVSCGRGIKQREIACVYQNQTKL-----EEAHCSHLQRPRTQKACRARICPTWKTSRWRECSVTCGFGVQNRDVYCRLKGAGRVRED-LCDAGTRPLFLQPCHTAE-CTHYTWVTGEWDKCNVSCGDGTRSRKVWC 1546

HSP 5 Score: 82.8037 bits (203), Expect = 3.278e-15
Identity = 81/292 (27.74%), Postives = 119/292 (40.75%), Query Frame = 1 
Query: 2653 RPIEELNC-VGQCNPLLWSYGKWEECPIECGTTFRYRNFICKDNKGLEWQKEWCERHLGLPDNKETCLSFNNCRNLTRWVTSPWSRCSNSCESELQKRMVYCFRSEKSDEILDEKFLKIHEQISDAFCDIHSPKPITERPCSLNSCYFWIXXXXXXXXXXXXLGFRIQSHECKKKFNKNHEMITVDDKFCLKQNLVKPLDVRMRCFLKKCAIES----FWIEMEWSKCSVSCGEGLQYRSLKCGYENENKTLTTWDNNEMCKNKMVPVSIQICKVTPCP-KWIYSEWSECEG 3510
            +P E  +C  G C   LW+YG W EC   CG   R R  +C+   G       C+  L  P + E C +   C     W   PW  CS SC   +++R + C    ++             ++ +A C  H  +P T++ C    C  W  S+  +CS  CG G + +   C+ K         V +  C      +PL      FL+ C         W+  EW KC+VSCG+G + R + C          T   N+ C+    P S+Q C    C   W+  EWS+  G
Sbjct: 1335 KPAESKSCDSGPCP--LWNYGVWGECTQPCGGGRRTRLVVCQRPNGETLIDYNCDM-LDKPLDMEQC-NLQPCPGSASWHRQPWKPCSVSCGRGIKQREIACVYQNQT-------------KLEEAHCS-HLQRPRTQKACRARICPTWKTSRWRECSVTCGFGVQNRDVYCRLKGAGR-----VREDLC--DAGTRPL------FLQPCHTAECTHYTWVTGEWDKCNVSCGDGTRSRKVWCAGPE-----MTPAQNDYCEPSSRPPSVQSCTEAACQYVWVTGEWSQVRG 1590
[Close]
BLAST of A disintegrin and metalloproteinase with thrombospondin motifs vs. Ensembl Medaka
Match: adamts9 (ADAM metallopeptidase with thrombospondin type 1 motif 9 [Source:NCBI gene;Acc:101171570])

HSP 1 Score: 373.629 bits (958), Expect = 6.265e-105
Identity = 337/1343 (25.09%), Postives = 532/1343 (39.61%), Query Frame = 1 
Query:  535 PNIIELLIVVTSNFVKRFKKDFRQYILSNVAIATKLLHDPTIKASITXXXXXXXXXXEDYERNNDLHDWSLLS--QDRVVSRFCHWVRQKKQL---WNYSWDSAILINDGVF-----SSNAIGIAHLRSMCND-NNCLAVVDRGFGTGFIIAHELAHQMNARHDFDNAEACSFFEKQYDNKTKYNTIMSTSLFFEYYPFIWSVCSQNVINSFLKSKYSFCLKQRNRHRNLYPHEQINEFFQKYSTGVDYDLNEQCSFAFGEKSEFCETDQNSRK------KCSVLYCRLKRYPICLRADAIIADGTECDVNQHCINGKCLYKNITIAPIDGGWSEYSEWSNCSRPCNGGVQFSYRTCDNPVPADGGRFCTGTKERIRSCNIEECS-SFSDPREESCGKYNLKPY----IPTNDEEFP----------CNLVCITTNHSLKYDI--SLTDGTPCSPFRSDICVKGTCYKTGCDRIVGSKKAIDNCNICAGQNDTCFKKESFFDGSKVAKVRMIRAFRIPPNVYNLFIKKVSQRMTPFTDEVYDDFELLLVVNRRTVIRRSETIEPLAGGQLR-------YSGSKNKVETISIKGKLNVGISIVIKVENTKTTLNLPFISYHYFV-----KDIFVWKYLEVITHPCKDQCGGFIEISPACFKKRDNQRYVDHYCSKATKPEPKIIKCGAICGYRWQRATEHYINSTVNKSCPIRCGTGKVKIPFVCQKINNQDDNNSLWETVEENLCFAVDLVDRPIEELNCVGQCNPLLWSYGKWEECPIECGTTFRYRNFICKD------------------------------------------NKGLEWQKEWCE--------RHLGLPDNKETCLSFNNCRNLTRWVTSPWSRCSNSCESELQKRMVYCFRSEKSDEILDEKFLKIHEQISDAFCDI------HSPKPITERPCSLNSCYFWIXXXXXXXXXXXXLGFRIQSHECKKKFNKNHEMITVDDKFCLKQNLVKPLDVRMRCFLKKCAIESFWIEMEWSKCSVSCGEGLQYRSLKCGYENENKTLTTWDNNEMCKNKMVPVSIQICKVTPCP-------------------------KWIYSEWSECEGTCEYGSQHRTVLCTDPISEQILPDSKCDIKNKFPNFQKCLLSKLCGHWIVGKWSQCSASCGLGVKTRTITCNYSNGSKSIDHSVCKSVAPFEEIHCQVKPCSTNAFWWLVKPSECYEYNCQPGIMYAHVRCVNRKFQVLYDSKCSRIK-HPSYYVGCLNTTCRRYFWTAESWDNIPCPDISCTMKIRNRDVYCVDDYGNIQKDAMCDQSDKPDTWRLCPSPQNC 4179
            P  +E+++V  S  V+    + + YIL+ ++I + +  DP+I   I I +V +V++       N+  +  ++S      +  FC W + +  L    +   D+AILI            + +G+A L ++C+   +C    D G  T F IAHEL H  N  HD  +++ C     + D       +M+ +L +   P++WS CS+  I  FL + Y  CL      R     +Q+         G  Y +N+QC   FG  ++ C      R+      + +   CR +  P         ADGT+C    HC +G C+ K     P++G W  +S +  CSR C GG++ + R C+ PVP +GG +C G + + RSCN E CS    D REE C  ++ + +    +P N    P          C L C     +  Y +   +TDGTPC P  +DICV+G C + GCD ++ SK   D C IC G N +C   ++  D   + +       RIP    N+ +++ S     ++ +  DD  L +  +R   +   E +  +   +++       YSGS + +E I+   ++     ++I+V +     N P + Y + +        F W         C   C G  +    C ++ D     D  C    +P      C   C  RW  A +          C  +CG G   +   C KI++        + ++   C       +P ++ +C G CNP  W Y  W EC   CG   R+R  IC+                                            KG + ++ WC+        R  G P  K   +     +    W   PW +C+ SC    Q R V C     +  + D +        +   C++      H   P T+ P        W       CSA CG G  ++   C     ++ +    DD  C   +L KP    + C +  C     W  +EW+ CSV+CG+GL  R + C   NE +      N   C     P + Q C ++ CP                         +W    W  C  TC  G Q R V+C D   E   P + C+  ++ PN Q+   S  C  W  G W +C+  CG G+KTR + C   NG +  D S      P ++  C  +PC ++  W     S C   +C  G     V CV    + + +  C  +   PS    C    C +  W   SW        SC   ++ R+V C D+      +  C Q  +P      PS Q+C
Sbjct:  302 PRFVEVMVVADSKMVEHHGSNLQHYILTLMSIVSSIYKDPSIGNLINIVIVKLVII-------NNEQEGPVISFNAQTTLKNFCIWQQSQNMLDDSHHSHHDTAILITRQDICRARDKCDTLGLAELGTVCDPYRSCSISEDNGLSTAFTIAHELGHVFNMPHD--DSKKC-----KEDGVKIQQHVMAPTLNYNTNPWMWSKCSRKYITEFLDTGYGECLLDEPVSRPYTLSQQL--------PGQIYSVNKQCELIFGPGTQVCPYMTQCRRLWCTSPEGAQRGCRTQHMPW--------ADGTDCSPGNHCKHGLCIAKEHDTTPVEGAWGVWSPFGTCSRTCGGGIKIAVRECNRPVPRNGGMYCVGRRMKFRSCNSEPCSKQKKDFREEQCATFDGRHFNINGLPPNVRWVPKYSGILMKDRCKLFCRAAGSTAYYQLRDRVTDGTPCGPDTNDICVQGLCRQAGCDHVLNSKARRDKCGICGGDNSSC---KTVADTFNIVRYGYNEVVRIPSGATNIDVRQHS-----YSGKSDDDNYLAVSNSRGEFLLNGEFVVSMFKREIKVGNTVIEYSGSDHVIERINCTDRIEE--EVIIQVLSVGNLYN-PNVRYSFNIPIEDKPQQFFWDAYGPWQE-CSHLCQGERKRKILCSRESDRVVVSDQRCYGTGRPAVVTEPCNTECELRWYVARK--------SECTAQCGHGYRTLEIYCAKISHGKT-----QKIDGRFCSG---QHKPEDKESCHGDCNPGGWEYSPWSECSKSCGGGTRHRGAICRKAAESGGDDSKCSQRDKLTIQPCNEFLCPQWKTGEWSECLVTCGKGYKHRQAWCQFGEDRLDDRFCGSP--KPESVQMCQQQECASWQVGPWGQCTTSCGPGYQMRAVKCVVGSYAAVMDDTECNAATRPTNTQDCEVAQCPNSHPVPPGTKVPSHQGHKTQWRFGSWAPCSASCGKGTWMRFVSC-----RDDQGGLADDSACA--HLPKPPASGV-CSVVACGQ---WKVLEWTLCSVTCGQGLTTRQVLCVDFNEQEV-----NASECDPDDRPTTQQDCAMSQCPSRSSESRPLPSSPNARSSLPHSQSHQWRTGPWGACSSTCAGGFQRRVVVCQD---ENGYPANSCEDSSR-PNEQRSCESGPCPQWAYGSWGECTKPCGGGIKTRLVVCQRPNGERFNDLSCEIHDKPPDQEQCNTQPCPSSPHWSTDPWSSC-SASCGRGFKSRKVSCVTGSGRAVPEENCQHLSPKPSKQRRCRGGRCPK--WKTGSWGEC---SASCGDGVQQREVSCHDEGHRSPLETGCTQRSRP------PSSQSC 1552

HSP 2 Score: 196.052 bits (497), Expect = 1.102e-49
Identity = 185/725 (25.52%), Postives = 294/725 (40.55%), Query Frame = 1 
Query: 2701 WSYGKWEECPIECGTTFRYRNFICKDNKGLEWQKEWCERHLGLPDNKETCL---SFNNCRNLT----------------------RWVTSPWSRCSNSCESELQKRMVYCFRSEKSDEILDEKFLKIHEQISDAFCDIHSPKPITERPCSLNSCYFWIXXXXXXXXXXXXLGFRIQSHECKKKFNKNHEMITVDDKFCLKQNLVKPLDVRMRCFLKKCAIESFWIEMEWSKCSVSCGEGLQYRSLKCGYENENKTLTTWDNNEMCKN-KMVPVSIQICKVTPCPKWIYSEWSECEGTCEYGSQHRTVLCTDPISEQILPDSKCDIKNKFPNFQKCLLSKLCGH--WIVGKWSQCSASCGLGVKTRTITCNYSNGSKSIDHSVCKSVAPFEEIHCQVKPCSTNAFWWLVKPSECYEYNCQPG----IMY---AHVRCVNRKFQVLYDSKCSRIKHPSYYVGCLNTTCR-RYFWTAESWDNIPCPDISCTMKIRNRDVYCVDDYGNIQKDAMCDQSDKPDTWRLCPSPQNCSNIPRSCKELKSRQSVSKDGEYSLAIDLNWAYFIYCADMNTEEPKEYLTL---RELNYARTSKYVSTDVSSCIYEEEMEFNQKCPTCKINENLWSITYYNKIRINLSDLSIDVMDDRFSATNGQSFIPFGTAKDCAGSTSCPKGHFKINLRGTGFSVSMETRWNEVYPKYGYRILRKQTSQIVKGWCGGHCSGCSP 4758
            W   +W  C + CG     R  +C D    E     C+     PD++ T     + + C + +                      +W T PW  CS++C    Q+R+V C          DE     +       C+  S +P  +R C    C  W     G+C+  CG G + +   C++   +       +D  C   +  KP D + +C  + C     W    WS CS SCG G + R + C      + +      E C++    P   + C+   CPKW    W EC  +C  G Q R V C D      L ++ C  +++ P+ Q C ++       W  G+W  CS SCG G + R++ C   N  +  +      + P     C    C     W   + +EC    C  G    ++Y    H+   N ++     S C     P  Y+ C    C     W    W       +SC   +  R V+CV   G  Q+   C +   P+T +LC  P    ++P SC +++  + +  DGE+ L++    A  ++CA M TE P+EY+TL      N++    +   D + C         + C  C+ +      T ++K+R++L  +SI   D +F++++    +PF TA DC  +  CP+G F INL GTG  +S    W          I + Q    V G CGG+C  C+P
Sbjct: 1253 WKVLEWTLCSVTCGQGLTTRQVLCVDFNEQEVNASECD-----PDDRPTTQQDCAMSQCPSRSSESRPLPSSPNARSSLPHSQSHQWRTGPWGACSSTCAGGFQRRVVVC---------QDENGYPANS------CE-DSSRPNEQRSCESGPCPQWAYGSWGECTKPCGGGIKTRLVVCQRPNGER-----FNDLSCEIHD--KPPD-QEQCNTQPCPSSPHWSTDPWSSCSASCGRGFKSRKVSC-VTGSGRAVP----EENCQHLSPKPSKQRRCRGGRCPKWKTGSWGECSASCGDGVQQREVSCHDEGHRSPL-ETGCTQRSRPPSSQSCRVADCPSRYRWKEGEWQTCSKSCGTGRRQRSLQCVDLNQQEVHEIYCVNEIRPPNMESCNTHAC--ELIWITGEWTEC-SATCGRGYRQRLVYCSEVHLENNNYEYSHQSLSNCPG-SPPESYMPCKLIPCPPTQEWRVGIWGEC---SVSCGDGVMERMVHCVSADG--QESNRCSEDAMPETQKLCRKPS--CHLPSSCLDIQRLKGLLPDGEHFLSVQGK-ALKVFCAGMQTETPQEYITLATGEGENFSEIFAFRLNDPTQCPANGSRR--EDC-DCRRDYTAAGFTSFSKVRLDLRRMSIITADWQFASSHESKDVPFATAGDCYSAAGCPQGRFSINLSGTGLKLSEGISWISHGNYAVINIHKSQDGSRVSGTCGGYCGKCTP 1927

HSP 3 Score: 55.8398 bits (133), Expect = 5.542e-7
Identity = 50/225 (22.22%), Postives = 85/225 (37.78%), Query Frame = 1 
Query: 2326 CKDQCGGFIEISPACFKKRDNQRYVDHYCSKATKPEP----KIIKCGAICGYRWQRATEHYINSTVNKSCPIRCGTGKVKIPFVCQKINNQDDNNSLWETVEENLCFAVDLVDRPIEELNCVGQCNPLLWSYGKWEECPIECGTTFRYRNFICK----DNKGLEWQKEWCERHLGLPDNKETCLSFNNCRNLTRWVTSPWSRCSNSCESELQKRMVYCFRSEKSD 2976
            C   CG  ++          ++  ++  C++ ++P      ++  C +   YRW+            ++C   CGTG+ +    C  +N Q+        V E  C  V+ + RP    +C      L+W  G+W EC   CG  +R R   C     +N   E+  +      G P           C     W    W  CS SC   + +RMV+C  ++  +
Sbjct: 1512 CSASCGDGVQQREVSCHDEGHRSPLETGCTQRSRPPSSQSCRVADCPSR--YRWKEGEW--------QTCSKSCGTGRRQRSLQCVDLNQQE--------VHEIYC--VNEI-RPPNMESCNTHACELIWITGEWTECSATCGRGYRQRLVYCSEVHLENNNYEYSHQSLSNCPGSPPESYMPCKLIPCPPTQEWRVGIWGECSVSCGDGVMERMVHCVSADGQE 1715
[Close]
BLAST of A disintegrin and metalloproteinase with thrombospondin motifs vs. Ensembl Medaka
Match: ADAMTS20 (A disintegrin and metalloproteinase with thrombospondin motifs 20 [Source:NCBI gene;Acc:101170674])

HSP 1 Score: 363.614 bits (932), Expect = 8.632e-102
Identity = 339/1304 (26.00%), Postives = 522/1304 (40.03%), Query Frame = 1 
Query:  535 PNIIELLIVVTSNFVKRFKKDFRQYILSNVAIATKLLHDPTIKASITXXXXXXXXXXEDYERNNDLHDWSLLSQDRVVSRFCHWVRQKKQLWNYS----WDSAILIND-----GVFSSNAIGIAHLRSMCND-NNCLAVVDRGFGTGFIIAHELAHQMNARHDFDNAEACSFFEKQYDNKTKYNTIMSTSLFFEYYPFIWSVCSQNVINSFLKSKYSFCLKQRNRHRNLYPHEQINEFFQKYSTGVDYDLNEQCSFAFGEKSEFCETDQNSRKKCSVLYCRLKR--YPICLRADAIIADGTECDVNQHCINGKCLYKNITIAPIDGGWSEYSEWSNCSRPCNGGVQFSYRTCDNPVPADGGRFCTGTKERIRSCNIEECS-SFSDPREESCGKYNLKPY----IPTNDEEFP----------CNLVCITTNHSLKYDIS--LTDGTPCSPFRSDICVKGTCYKTGCDRIVGSKKAIDNCNICAGQNDTCFKKESFFDGSKVAKVRMIRAFRIPPNVYNLFIKKVSQRMTPFTDE--VYDDFELLLVVNRRTVIRRSETIEPLAGGQLRYSGSKNKVETISIKGKLNVGISI-VIKVEN-----TKTTLNLPFISYHYFVKDIFVW----KYLEVITHPCKDQCGGFIEISPACFKKRDNQRYVDHYCSKATKPEPKIIKCGAICGYRWQRATEHYINSTVNKSCPIRCGTGKVKIPFVCQKINNQDDNNSLWETVEENLCFAVDLVDRPIEELNCVGQCNPLLWSYGKWEECPIECGTTFRYRNFICKDNKGLEWQKEWCERHLGLPDNKETCLSFNNCRNL--TRWVTSPWSRCSNSCESELQKRMVYCFRSEKSDEILDEKFLKIHEQISDAFCDIHSPKPITERPCSLNSCYFWIXXXXXXXXXXXXLGFRIQSHECKKKFNKNHEMITVDDKFCLKQNLVKPLDVRMRCFLKKCA----------------IESFWIEMEWSKCSVSCGEGLQYRSLKCGYENENKTLTTWDNNEMCKNKMVPVSIQICKVTPCPKWIYSEWSECEGTCEYGSQHRTVLCTDPISEQILPDSKCDIKNKFPNFQKCLLS-------------------KLCGH---------------WIVGKWSQCSASCGLGVKTRTITCNYSNGSKSIDHSVC-KSVAPFEEIHCQVKPCSTNAFWWLVKPSECYEYNCQPGIMYAHVRCVNRKFQVLYDSKCSRIKHPSYYVGCLNTTC-RRYFWTAESWDNIPCPDISCTMKIRNRDVYCVDDYGNIQKDAMCDQSDKPDTWRLC 4161
            P  +EL++   +   +   ++   YIL+ +++   +  DP++   I I VV +V++  + E      D +       +  FC W +Q + +   S     D+A+LI            + +G+A L +MC+   +C    + G    F IAHEL H  N  HD  ++  C    ++   K +Y+ +M+ +L ++  P+ WS CS+  I  FL + Y  CL          P  +I E       G  Y+ N QC   FG  S+ C       K+C  L+C      +  C      +ADGT+C    +C +G C+ K + + P+ G W  +  +S CSR C GG + + R C  P P +GGRFC G + + RSCN E C     D REE C +++ K +    +  N    P          C L C      + Y +   + DGTPC P   DICV+G C + GCD ++ SK   D C +C G N +C      F+ ++     ++   RIP    N+ IK+VS    P  D      D +   ++N   V+   +    L G  + YSGS  KVE I+   ++   I + V+ V N      + + N+P   +    ++ F+W     +LE     C   C G       CF++ D+    D  C    +P      C A C  RW  A +          C  +CG G   +   C K +     +   E VE + C     + +P    +C G C    W Y  W +C   CG   R R   C +N G       C             +    C +L   +W  + WS C  +C   ++ R+V C   E+             E++S+ +CD+ S KP     C L  C  W     G C+  CG G+++++  C      N    TVDD+ C      +P D +  C +  C                 + + W    W+ CSVSCG+G Q R + C   N    +    +   C +   P     C  +PC +W   EWS C  TC  G   R V+C++      +  S CD  +K    Q+C                      +  GH               W  G W  CS++C  G + R + C   +G     +S C + + P E   C   PC     W      EC +  C  G     V C     + L D  C  +  P     C    C     W  + W   PC  +SC   I+ R++ CV       ++A C    +P T + C
Sbjct:  132 PRYVELMVTADAKMAQHHGRNLEHYILTIMSVVAAVYKDPSVGNLINIMVVKLVIIHNEQEGPTVSFDAAT-----TLHNFCVW-QQNQNVQEDSDPSHHDTALLITREDICRAKHKCDTLGLAELGTMCDPYRSCSISEENGISASFTIAHELGHVFNMPHD--DSPMC----REAGMKHQYH-VMAPTLNYDTNPWSWSKCSRKYITEFLDTGYGECLLDE-------PVGRIYEL-PTLLPGQIYNANRQCELMFGPGSQICPY----MKQCKRLWCTSSEGDHKGCRTQHMPLADGTDCGHGMYCRHGMCVNKELDLQPVHGEWGPWGPYSACSRSCGGGTRSATRDCKKPEPRNGGRFCVGRRMKFRSCNTEPCPRGKKDFREEQCSQFDGKHFNINGLTPNVRWVPKYSGILMKDRCKLFCRVAGAMMYYQLKDRVIDGTPCGPDTYDICVQGLCRQAGCDHVLNSKARNDKCGVCGGDNSSCKTLAGTFNDAQYGYNTVV---RIPAGATNIDIKQVSYSGKPEDDSYLALSDSQSNFLLNGNFVVSMFKREITLKGTVIEYSGSDTKVERINCTDRIEEEIILQVLCVGNPHNPDVRYSFNIPIEEH----REQFLWDPSGSWLE-----CSRMCHGERRRKAVCFRQSDHLEVSDQRCEHLPRPVAVTEPCNADCEVRWHVAGK--------SECSAKCGPGHRSLDIQCMKYSLLQRES---ERVEASACAE---IPKPHTRESCHGDCLLKSWQYSAWTQCSKTCGRGSRSRESYCMNNLGRRLVDRECSEFQR--------VVIETCNDLPCPQWTVNEWSECLVTCGKGMKHRLVTCMGGEE-------------EKLSEQYCDL-STKPAATESCQLPECASWQVGIWGACAVTCGHGYQMRAVRCVLGDYGN----TVDDREC--NAAARPRDSQ-ECEMPACPWISPVQSTPRPDNSAQLHTQWRYGSWTACSVSCGKGKQARYVTC--INAQGAVA---DESYCAHLPRPPEFSTC-FSPCGQWHAREWSTCSVTCGVGRATRQVVCSN--YHHPVDQSFCDNDDKPATEQECTAGPCPSVYNRQRIYEQPYGYPQDPGHHPGHSSWNVPSADNQWRTGPWGACSSTCEGGFQRRVVVCQDGDGR---SNSYCDERIKPAESKSCDSGPC---PLWNYGVWGECTQ-PCGGGRRTRLVVCQRPNGETLIDYNCDMLDKPLDMEQCNLQPCPGSASWHRQPWK--PC-SVSCGRGIKQREIACVYQNQTKLEEAHCSHLQRPRTQKAC 1337

HSP 2 Score: 222.246 bits (565), Expect = 8.812e-58
Identity = 209/765 (27.32%), Postives = 310/765 (40.52%), Query Frame = 1 
Query: 2518 SCPIRCGTGKVKIPFVCQKINNQDDNNSLWETVEENLCFAVDLVDRPIEELNCVGQCNPLLWSYGKWEECPIECGTTFRYRNFICK-----------DNKGLEWQKEWC---------------ERHLGLPDN---KETCLSFNNCRNLTRWVTSPWSRCSNSCESELQKRMVYCFRSE-KSDEILDEKFLKIHEQISDAFCDIHSPKPITERPCSLNSCYFWIXXXXXXXXXXXXLGFRIQSHECKKKFNKNHEMITVDDKFCLKQNLVKPLDVRMRCFLKKCAIESFWIEMEWSKCSVSCGEGLQYRSLKCGYENENKTLTTWDNNEMCKNKMVPVSIQICKVTPCPKWIYSEWSECEGTCEYGSQHRTVLCTDPISEQILPDSKCDIKNKFPNFQKCLLSKLCGH--WIVGKWSQCSASCGLGVKTRTITCNYSNGSKSIDHSVCKSVAPFEEIHCQVKPCSTNAFWWLVKPSECYEYNCQPGIMYAHVRCV---NRKFQVLYDS------KCSRIKHPSYYVGCLNTTCRRYFWTAESWDNIPCPDISCTMKIRNRDVYCVDDYGNIQKDAMCDQSDKPDTWRLCPSPQNCSNIPRSCKELKSRQSVSKDGEYSLAIDLNWAYFIYCADMNTEEPKEYLTLRELNYARTSKYVSTDVSSCIYEEEMEFNQKCP---------TCKINENLWSITYYNKIRINLSDLSIDVMDDRFSATNGQSFIPFGTAKDCAGSTSCPKGHFKINLRGTGFSVSMETRWN 4662
            +C + CG GK      C  IN Q          +E+ C  +    RP E   C   C    W   +W  C + CG     R  +C            DN      ++ C               E+  G P +        S+N      +W T PW  CS++CE   Q+R+V C   + +S+   DE+                  KP   + C    C  W     G+C+  CG G R +   C++   +     T+ D  C    L KPLD+  +C L+ C   + W    W  CSVSCG G++ R + C Y+N+ K          C +   P + + C+   CP W  S W EC  TC +G Q+R V C    + ++  D  CD   +    Q C  ++ C H  W+ G+W +C+ SCG G ++R + C     + + +     S  P     C    C     W   + S+C    C  G    +V C    +   Q LY        KC     P      L       +W A  W        +C   +  R V C+   G  Q   +C  S++P +   C   Q    +  SC+E++ RQ V  +GEY L +       IYCA+M T+ PKEY+TLR            TD  S +Y   +    +CP         +C+ + +    T ++K+R++LS L I + D +FS T     +PF TA DC  +  CP+G F INL GTG  V+  T+W 
Sbjct: 1038 ACSVSCGKGKQARYVTC--INAQG------AVADESYCAHLP---RPPEFSTCFSPCG--QWHAREWSTCSVTCGVGRATRQVVCSNYHHPVDQSFCDNDDKPATEQECTAGPCPSVYNRQRIYEQPYGYPQDPGHHPGHSSWNVPSADNQWRTGPWGACSSTCEGGFQRRVVVCQDGDGRSNSYCDERI-----------------KPAESKSCDSGPCPLWNYGVWGECTQPCGGGRRTRLVVCQRPNGE-----TLIDYNC--DMLDKPLDME-QCNLQPCPGSASWHRQPWKPCSVSCGRGIKQREIACVYQNQTKL-----EEAHCSHLQRPRTQKACRARICPTWKTSRWRECSVTCGFGVQNRDVYCRLKGAGRVRED-LCDAGTRPLFLQPCHTAE-CTHYTWVTGEWDKCNVSCGDGTRSRKVWCAGPEMTPAQNDYCEPSSRPPSVQSCTEAAC--QYVWVTGEWSQC-SVTCGIGYQQRYVSCSMIPSSPGQGLYAQTPIAAEKCLEPSPPGTRPCVLRECSNTAYWKAGPWSKC---SQTCGAGLMERRVECMTLKG--QPSKVCHHSERPASQAACQDRQ--CQLFTSCREVQMRQGVRMNGEYYLKVKSR-ILQIYCAEMQTDFPKEYVTLRSGQ---------TDNYSEVYGYRLLNPFECPNNGSRLQDCSCRNDYSAAGYTLFHKVRLDLSSLRIMITDLQFSQTLLGRPVPFATAGDCYSAAKCPQGQFSINLTGTGLKVAPATKWT 1737

HSP 3 Score: 130.183 bits (326), Expect = 1.060e-29
Identity = 136/492 (27.64%), Postives = 207/492 (42.07%), Query Frame = 1 
Query: 2821 LGLPDNKETCLSFN----NCRNLTRWVTS-PWSRCSNSCESELQKRMVYCFRSEKSDEILDEKFLKIHEQISDAFCDIHSPKPIT-ERPCSLNSCYFWIXXXXXXXXXXXXLGFRIQSHECKKKFNKNHEMITVDDKFCLKQNLVKPLDVRMRCFLKKCAIESFWIEMEWSKCSVSCGEGLQYRSLKCGYENENKTLTTWDNNEMCKNKMVPVSIQICKVTPCPKWIYSEWSECEGTCEYGSQHRTVLCTDPISEQILPDSKCDIKNKFPNFQKCLLSKLCGHWIVGKWSQCSASCGLGVKTRTITCNYSNGSKSIDHSVCKSVA-PFEEIHCQVKPC----------------STNAFWWLVKPSECYEYNCQPGIMYAHVRCVNRKFQVLYDSKCSRIKHPSYYVGCLNTTCRRYFWTAESWDNIPCPDISCTMKIRNRDVYCVDDYGNIQKDAMCDQSDKPDTWRLCPSPQNCSNIPRSCKELKSRQSV 4227
            +G P N +   SFN      R    W  S  W  CS  C  E +++ V CFR  +SD          H ++SD  C+ H P+P+    PC+ +    W  +   +CSAKCG G R    +C K      E   V+   C +  + KP   R  C    C ++S W    W++CS +CG G + R   C   N  + L   + +E  +     V I+ C   PCP+W  +EWSEC  TC  G +HR V C     E+ L +  CD+  K    + C L + C  W VG W  C+ +CG G + R + C   +   ++D   C + A P +   C++  C                  +  W     + C   +C  G    +V C+N +  V  +S C+ +  P  +  C +   +   W A  W       ++C +    R V C  +Y +    + CD  DKP T       Q C+  P  C  + +RQ +
Sbjct:  699 VGNPHNPDVRYSFNIPIEEHREQFLWDPSGSWLECSRMCHGERRRKAV-CFR--QSD----------HLEVSDQRCE-HLPRPVAVTEPCNADCEVRWHVAGKSECSAKCGPGHRSLDIQCMKYSLLQRESERVEASACAE--IPKP-HTRESCH-GDCLLKS-WQYSAWTQCSKTCGRGSRSRESYC-MNNLGRRLVDRECSEFQR-----VVIETCNDLPCPQWTVNEWSECLVTCGKGMKHRLVTCMGG-EEEKLSEQYCDLSTKPAATESCQLPE-CASWQVGIWGACAVTCGHGYQMRAVRCVLGDYGNTVDDRECNAAARPRDSQECEMPACPWISPVQSTPRPDNSAQLHTQWRYGSWTAC-SVSCGKGKQARYVTCINAQGAVADESYCAHLPRPPEFSTCFSPCGQ---WHAREWSTC---SVTCGVGRATRQVVC-SNYHHPVDQSFCDNDDKPAT------EQECTAGP--CPSVYNRQRI 1147

HSP 4 Score: 58.5362 bits (140), Expect = 7.950e-8
Identity = 67/262 (25.57%), Postives = 98/262 (37.40%), Query Frame = 1 
Query: 2323 PCKDQCGGFIEISPACFKKRDNQRYVDHYCSKATKPEPKIIKCGAICGYRWQRATEHYINSTVNKS----CPIRCGTGKVKIPFVCQKINNQDDNNSLWET--VEENLCFAVDLVDRPIEELNC-VGQCNPLLWSYGKWEECPIECGTTFRYRNFICKDNKGLEWQKEWCERHLGLPDNKETCLSFNNCRNLTRWVTSPWSRCSNSCESELQKRMVYCFRSEKSDEILDEKFLKIHEQISDAFCDIHSPKPITERPCSLNSC 3087
            PC   CG  I+        ++  +  + +CS   +P             R Q+A    I  T   S    C + CG G          + N+D    L     V E+LC   D   RP+    C   +C    W  G+W++C + CG   R R   C   +    Q ++CE     P + ++C     C+ +  WVT  WS+CS +C    Q+R V C        I       ++ Q   A      P P   RPC L  C
Sbjct: 1296 PCSVSCGRGIKQREIACVYQNQTKLEEAHCSHLQRP-------------RTQKACRARICPTWKTSRWRECSVTCGFG----------VQNRDVYCRLKGAGRVREDLC---DAGTRPLFLQPCHTAECTHYTWVTGEWDKCNVSCGDGTRSRKVWCAGPEMTPAQNDYCEPS-SRPPSVQSCTEA-ACQYV--WVTGEWSQCSVTCGIGYQQRYVSC------SMIPSSPGQGLYAQTPIAAEKCLEPSPPGTRPCVLREC 1521
[Close]
BLAST of A disintegrin and metalloproteinase with thrombospondin motifs vs. Ensembl Medaka
Match: adamts10 (A disintegrin and metalloproteinase with thrombospondin motifs 10 [Source:NCBI gene;Acc:101172968])

HSP 1 Score: 269.24 bits (687), Expect = 1.863e-73
Identity = 259/973 (26.62%), Postives = 406/973 (41.73%), Query Frame = 1 
Query:  301 FIKPNTKTKFNSKFLKTEMNFLPHKIY-FTALNLNKPLFSCKLLKNNGYRNIPQESHFSRVFQR----MKRETYPVVDSEIVEPNIIELLIVVTSNFVK-RFKKDFRQYILSNVAIATKLLHDPTIKASITXXXXXXXXXXEDYERNNDLHDWSLLSQDRVVSRFCHWVRQKKQLWNYS----------WDSAILIN--DGVFSSN----AIGIAHLRSMCN-DNNCLAVVDRGFGTGFIIAHELAHQMNARHDFDNAEACSFFEKQYDNKTKYNTIMSTSLFFEYYPFIWSVCSQNVINSFLKSKYSFCLKQRNRHRNLYPHEQINEF-FQKYSTGVDYDLNEQCSFAFGEKSEFCETDQNSRKKCSVLYCRLKRYPICLRADAIIADGTECDVNQ----HCINGKCLYKNITIAPIDGGWSEYSEWSNCSRPCNGGVQFSYRTCDNPVPADGGRFCTGTKERIRSCNIEECSSFS-DPREESC---------GK-YNLKPYIPTNDEEFPCNLVCITTNHSL--KYDISLTDGTPCSPFRSDICVKGTCYKTGCDRIVGSKKAIDNCNICAGQNDTCFKKESFFDGSKVAKVRMIRAFRIPPNVYNLFIKKVSQRMTPF-----TDEVYDDFELLLVVNRRTVIRRSETIEPLAGGQLRYSGSKNKVETISIKGKLNVGISIVIKVENTKTTLNLPF-ISYHYFVKDIFVWKYLEVITHPCKDQCGGFIEISP-ACFKKRDNQRYVDHYCSKATKPEPKIIKCGA-ICGYRWQRATEHYINSTVNKSCPIRCGTGKVKIPFVCQKINNQDDNNSLWETVEENLCFAVDLVDRPIEELNCVGQCNPLLWSYGKWEECPIECGTTFRYRNFICKDNK-GLEWQKEWCERHLGLPDNKETCLSFNNCRNLTR-----WVTSPWSRCSNSCESELQKRMVYCF--RSEKSDEILDEKFLKIHEQISDAFCDIHSP 3048
             + P+ +TK        E    PH +Y  ++L       SC ++     +++   S + R  +     + R   P+  S + +   +E L+V     V    ++D  QYIL+ + I  KL  D ++  ++ I V  ++LL ED       H        + +  FC W +  +   +Y            D+A+LI   D     N     +G+A +  MC  + +C    D G GT F IAHE+ H     HD      C    ++         +M+  +  +  PFIWS CS++ I SFL S    CL       N  P +Q  EF +   + G  YD +EQC F +G +S  C+  +     CS L+C + +   C+ +    A+GT C  N      C    C+        +DGGWS +S W  CSR C GGV  S R CD+P P  GG++C G ++R RSCNI+EC + S D RE  C         GK Y  KPY     +  PC+L C+   ++   +   ++ DGTPC     D+CV G C   GCDR++GS    D C IC G   +C   E  F+ S + +       RIP     + I++++  +        +D+ + + +L +   RR  +         AG    Y    +  ET+   G  N+ + +++ V      ++  F    +    + F W Y       C   C G ++I    C +  D+    +H+C K +KP+ K   C    C   W        + + N     R    K +I    +KI            ++++ C +     RP     C     P  W    W EC   CG  +R+R  +CK  + G    +  C +H G P ++  C       NL R     W+  PW  CS  C    + R+V C     + S+E LD +     +Q     CD++ P
Sbjct:  166 LVSPDNQTKTEGSERTEER---PHVVYKRSSLRHQYKGRSCGVIDEKPLKSL---SWWQRTLKTPPHLVGRGQLPLKRS-VSQERYVETLVVADKMMVGYHGRRDIEQYILAVMNIVAKLFQDSSLGNAVNIVVTRLILLMEDQPTLEINHH-----AGKSLDSFCKWQKSIQHRNSYGNAIPDNGIAHHDTAVLITRYDICIQKNKPCETLGLAPVGGMCEPERSCSINEDIGLGTAFTIAHEIGHTFGMNHD-GMGNTCGPRSQETAK------LMADHITMKTNPFIWSACSRDYITSFLDSGMGSCL-------NNVPLKQ--EFVYPTTAPGQAYDADEQCRFQYGIRSRQCKYSE----VCSELWC-MSKSNRCITSSIPAAEGTICQTNTIEKGWCYKRMCVAYGTRPEGVDGGWSLWSPWGECSRTCGGGVSSSVRHCDSPRPTIGGKYCLGERKRFRSCNIDECPAGSRDFREIQCSDFDNIPFRGKFYTWKPYRGGGVK--PCSLNCLAEGYNFYTERAPAVVDGTPCRDESLDMCVSGECKHVGCDRVLGSDVREDRCRICGGDGSSCVSVEGVFNDS-LPEGGYEEVVRIPKGSVFIHIQELNMSLNYLVLKSKSDQYFINGKLTIDTPRRFNV---------AGTTFHYRRPTDGPETLEALGPTNITLIVMVLVREENPGIHYRFNPPLNRDPLNGFSWFYTSWSR--CSVLCAGGVQIQQVVCKRLLDHTVVYNHFCDKKSKPKEKRRSCNTEPCSPTWWTGGWSECSRSCNGGLRTREVLCKRRISVTEEKI------------LDDSACSS----HRPSLTEPCNNHSCPPEWLALDWSECTPSCGPGYRHRVVLCKSGESGDILSESRCPKH-GRPTSRVRC-------NLKRCPPPQWIVGPWGECSAKCGLGQEMRLVQCLTHTGQPSNECLDHQRPAAMQQCRSK-CDLNLP 1066

HSP 2 Score: 93.2041 bits (230), Expect = 1.933e-18
Identity = 69/212 (32.55%), Postives = 100/212 (47.17%), Query Frame = 1 
Query: 3139 GFRIQSHECKKKFNKNHEMITVDDKFCLKQNLVKPLDVRMRCFLKKCAIESFWIEMEWSKCSVSCGEGLQYRSLKCGYENENKTLTTWDNNEMCKNKMVPVSIQICKVTPCP-KWIYSEWSECEGTCEYGSQHRTVLCTDPISEQILPDSKCDIKNKFPNFQKCLLSKLC--GHWIVGKWSQCSASCGLGVKTRTITCNYSNGSKS---IDH 3756
            G +IQ   CK+  +       V + FC K++  KP + R  C  + C+    W    WS+CS SC  GL+ R + C            D++    ++  P   + C    CP +W+  +WSEC  +C  G +HR VLC    S  IL +S+C    +  +  +C L K C    WIVG W +CSA CGLG + R + C    G  S   +DH
Sbjct:  848 GVQIQQVVCKRLLDHT----VVYNHFCDKKS--KPKEKRRSCNTEPCS--PTWWTGGWSECSRSCNGGLRTREVLCKRRISVTEEKILDDSACSSHR--PSLTEPCNNHSCPPEWLALDWSECTPSCGPGYRHRVVLCKSGESGDILSESRCPKHGRPTSRVRCNL-KRCPPPQWIVGPWGECSAKCGLGQEMRLVQCLTHTGQPSNECLDH 1048

HSP 3 Score: 80.8777 bits (198), Expect = 9.132e-15
Identity = 66/217 (30.41%), Postives = 92/217 (42.40%), Query Frame = 1 
Query: 3295 WIEMEWSKCSVSCGEGLQYRSLKCGYENENKTLTTWDNNEMCKNKMVPVSI-QICKVTPC-PKWIYSEWSECEGTCEYGSQHRTVLCTDPIS---EQILPDSKCDIKNKFPNFQKCLLSKLC-GHWIVGKWSQCSASCGLGVKTRTITCNYSNGSKSIDHSVC-KSVAPFEEIHCQVKPCSTNAFWWLVKP-SECYEYNCQPGIMYAHVRCVNRKFQ 3921
            W    WS+CSV C  G+Q + + C    ++  +     N  C  K  P    + C   PC P W    WSEC  +C  G + R VLC   IS   E+IL DS C   +  P+  +   +  C   W+   WS+C+ SCG G + R + C        +  S C K   P   + C +K C      W+V P  EC    C  G     V+C+    Q
Sbjct:  833 WFYTSWSRCSVLCAGGVQIQQVVCKRLLDHTVVY----NHFCDKKSKPKEKRRSCNTEPCSPTWWTGGWSECSRSCNGGLRTREVLCKRRISVTEEKILDDSACS--SHRPSLTEPCNNHSCPPEWLALDWSECTPSCGPGYRHRVVLCKSGESGDILSESRCPKHGRPTSRVRCNLKRCPPPQ--WIVGPWGEC-SAKCGLGQEMRLVQCLTHTGQ 1040

HSP 4 Score: 73.1738 bits (178), Expect = 2.332e-12
Identity = 63/235 (26.81%), Postives = 92/235 (39.15%), Query Frame = 1 
Query: 3478 WIYSEWSECEGTCEYGSQHRTVLCTDPISEQILPDSKCDIKNKFPNFQKCLLSKLCG-HWIVGKWSQCSASCGLGVKTRTITCNYS---NGSKSIDHSVCKSVAPFEEIHCQVKPCSTNAFWWLVKPSECYEYNCQPGIMYAHVRC-VNRKFQVLYDSKCSRIKHPSYYVGCLNTTCRRYFWTAESWDNIPCPDISCTMKIRNRDVYCVDDYGNIQKDAMCDQSDKPDTWRLCPS 4167
            W Y+ WS C   C  G Q + V+C   +   ++ +  CD K+K    ++   ++ C   W  G WS+CS SC  G++TR + C         K +D S C S  P     C    C     W  +  SEC   +C PG  +  V C       +L +S+C +   P+  V C    C    W    W         C +    R V C+   G  Q    C    +P   + C S
Sbjct:  833 WFYTSWSRCSVLCAGGVQIQQVVCKRLLDHTVVYNHFCDKKSKPKEKRRSCNTEPCSPTWWTGGWSECSRSCNGGLRTREVLCKRRISVTEEKILDDSACSSHRPSLTEPCNNHSCPPE--WLALDWSECTP-SCGPGYRHRVVLCKSGESGDILSESRCPKHGRPTSRVRCNLKRCPPPQWIVGPWGEC---SAKCGLGQEMRLVQCLTHTG--QPSNECLDHQRPAAMQQCRS 1059
[Close]
BLAST of A disintegrin and metalloproteinase with thrombospondin motifs vs. Ensembl Medaka
Match: adamts10 (A disintegrin and metalloproteinase with thrombospondin motifs 10 [Source:NCBI gene;Acc:101172968])

HSP 1 Score: 269.24 bits (687), Expect = 1.961e-73
Identity = 259/973 (26.62%), Postives = 406/973 (41.73%), Query Frame = 1 
Query:  301 FIKPNTKTKFNSKFLKTEMNFLPHKIY-FTALNLNKPLFSCKLLKNNGYRNIPQESHFSRVFQR----MKRETYPVVDSEIVEPNIIELLIVVTSNFVK-RFKKDFRQYILSNVAIATKLLHDPTIKASITXXXXXXXXXXEDYERNNDLHDWSLLSQDRVVSRFCHWVRQKKQLWNYS----------WDSAILIN--DGVFSSN----AIGIAHLRSMCN-DNNCLAVVDRGFGTGFIIAHELAHQMNARHDFDNAEACSFFEKQYDNKTKYNTIMSTSLFFEYYPFIWSVCSQNVINSFLKSKYSFCLKQRNRHRNLYPHEQINEF-FQKYSTGVDYDLNEQCSFAFGEKSEFCETDQNSRKKCSVLYCRLKRYPICLRADAIIADGTECDVNQH----CINGKCLYKNITIAPIDGGWSEYSEWSNCSRPCNGGVQFSYRTCDNPVPADGGRFCTGTKERIRSCNIEECSSFS-DPREESC---------GK-YNLKPYIPTNDEEFPCNLVCITTNHSL--KYDISLTDGTPCSPFRSDICVKGTCYKTGCDRIVGSKKAIDNCNICAGQNDTCFKKESFFDGSKVAKVRMIRAFRIPPNVYNLFIKKVSQRMTPF-----TDEVYDDFELLLVVNRRTVIRRSETIEPLAGGQLRYSGSKNKVETISIKGKLNVGISIVIKVENTKTTLNLPF-ISYHYFVKDIFVWKYLEVITHPCKDQCGGFIEISP-ACFKKRDNQRYVDHYCSKATKPEPKIIKCGA-ICGYRWQRATEHYINSTVNKSCPIRCGTGKVKIPFVCQKINNQDDNNSLWETVEENLCFAVDLVDRPIEELNCVGQCNPLLWSYGKWEECPIECGTTFRYRNFICKDNK-GLEWQKEWCERHLGLPDNKETCLSFNNCRNLTR-----WVTSPWSRCSNSCESELQKRMVYCF--RSEKSDEILDEKFLKIHEQISDAFCDIHSP 3048
             + P+ +TK        E    PH +Y  ++L       SC ++     +++   S + R  +     + R   P+  S + +   +E L+V     V    ++D  QYIL+ + I  KL  D ++  ++ I V  ++LL ED       H        + +  FC W +  +   +Y            D+A+LI   D     N     +G+A +  MC  + +C    D G GT F IAHE+ H     HD      C    ++         +M+  +  +  PFIWS CS++ I SFL S    CL       N  P +Q  EF +   + G  YD +EQC F +G +S  C+  +     CS L+C + +   C+ +    A+GT C  N      C    C+        +DGGWS +S W  CSR C GGV  S R CD+P P  GG++C G ++R RSCNI+EC + S D RE  C         GK Y  KPY     +  PC+L C+   ++   +   ++ DGTPC     D+CV G C   GCDR++GS    D C IC G   +C   E  F+ S + +       RIP     + I++++  +        +D+ + + +L +   RR  +         AG    Y    +  ET+   G  N+ + +++ V      ++  F    +    + F W Y       C   C G ++I    C +  D+    +H+C K +KP+ K   C    C   W        + + N     R    K +I    +KI            ++++ C +     RP     C     P  W    W EC   CG  +R+R  +CK  + G    +  C +H G P ++  C       NL R     W+  PW  CS  C    + R+V C     + S+E LD +     +Q     CD++ P
Sbjct:  161 LVSPDNQTKTEGSERTEER---PHVVYKRSSLRHQYKGRSCGVIDEKPLKSL---SWWQRTLKTPPHLVGRGQLPLKRS-VSQERYVETLVVADKMMVGYHGRRDIEQYILAVMNIVAKLFQDSSLGNAVNIVVTRLILLMEDQPTLEINHH-----AGKSLDSFCKWQKSIQHRNSYGNAIPDNGIAHHDTAVLITRYDICIQKNKPCETLGLAPVGGMCEPERSCSINEDIGLGTAFTIAHEIGHTFGMNHD-GMGNTCGPRSQETAK------LMADHITMKTNPFIWSACSRDYITSFLDSGMGSCL-------NNVPLKQ--EFVYPTTAPGQAYDADEQCRFQYGIRSRQCKYSE----VCSELWC-MSKSNRCITSSIPAAEGTICQTNTIEKGWCYKRMCVAYGTRPEGVDGGWSLWSPWGECSRTCGGGVSSSVRHCDSPRPTIGGKYCLGERKRFRSCNIDECPAGSRDFREIQCSDFDNIPFRGKFYTWKPYRGGGVK--PCSLNCLAEGYNFYTERAPAVVDGTPCRDESLDMCVSGECKHVGCDRVLGSDVREDRCRICGGDGSSCVSVEGVFNDS-LPEGGYEEVVRIPKGSVFIHIQELNMSLNYLVLKSKSDQYFINGKLTIDTPRRFNV---------AGTTFHYRRPTDGPETLEALGPTNITLIVMVLVREENPGIHYRFNPPLNRDPLNGFSWFYTSWSR--CSVLCAGGVQIQQVVCKRLLDHTVVYNHFCDKKSKPKEKRRSCNTEPCSPTWWTGGWSECSRSCNGGLRTREVLCKRRISVTEEKI------------LDDSACSS----HRPSLTEPCNNHSCPPEWLALDWSECTPSCGPGYRHRVVLCKSGESGDILSESRCPKH-GRPTSRVRC-------NLKRCPPPQWIVGPWGECSAKCGLGQEMRLVQCLTHTGQPSNECLDHQRPAAMQQCRSK-CDLNLP 1061

HSP 2 Score: 92.8189 bits (229), Expect = 2.135e-18
Identity = 69/212 (32.55%), Postives = 100/212 (47.17%), Query Frame = 1 
Query: 3139 GFRIQSHECKKKFNKNHEMITVDDKFCLKQNLVKPLDVRMRCFLKKCAIESFWIEMEWSKCSVSCGEGLQYRSLKCGYENENKTLTTWDNNEMCKNKMVPVSIQICKVTPCP-KWIYSEWSECEGTCEYGSQHRTVLCTDPISEQILPDSKCDIKNKFPNFQKCLLSKLC--GHWIVGKWSQCSASCGLGVKTRTITCNYSNGSKS---IDH 3756
            G +IQ   CK+  +       V + FC K++  KP + R  C  + C+    W    WS+CS SC  GL+ R + C            D++    ++  P   + C    CP +W+  +WSEC  +C  G +HR VLC    S  IL +S+C    +  +  +C L K C    WIVG W +CSA CGLG + R + C    G  S   +DH
Sbjct:  843 GVQIQQVVCKRLLDHT----VVYNHFCDKKS--KPKEKRRSCNTEPCS--PTWWTGGWSECSRSCNGGLRTREVLCKRRISVTEEKILDDSACSSHR--PSLTEPCNNHSCPPEWLALDWSECTPSCGPGYRHRVVLCKSGESGDILSESRCPKHGRPTSRVRCNL-KRCPPPQWIVGPWGECSAKCGLGQEMRLVQCLTHTGQPSNECLDH 1043

HSP 3 Score: 80.8777 bits (198), Expect = 9.348e-15
Identity = 66/217 (30.41%), Postives = 92/217 (42.40%), Query Frame = 1 
Query: 3295 WIEMEWSKCSVSCGEGLQYRSLKCGYENENKTLTTWDNNEMCKNKMVPVSI-QICKVTPC-PKWIYSEWSECEGTCEYGSQHRTVLCTDPIS---EQILPDSKCDIKNKFPNFQKCLLSKLC-GHWIVGKWSQCSASCGLGVKTRTITCNYSNGSKSIDHSVC-KSVAPFEEIHCQVKPCSTNAFWWLVKP-SECYEYNCQPGIMYAHVRCVNRKFQ 3921
            W    WS+CSV C  G+Q + + C    ++  +     N  C  K  P    + C   PC P W    WSEC  +C  G + R VLC   IS   E+IL DS C   +  P+  +   +  C   W+   WS+C+ SCG G + R + C        +  S C K   P   + C +K C      W+V P  EC    C  G     V+C+    Q
Sbjct:  828 WFYTSWSRCSVLCAGGVQIQQVVCKRLLDHTVVY----NHFCDKKSKPKEKRRSCNTEPCSPTWWTGGWSECSRSCNGGLRTREVLCKRRISVTEEKILDDSACS--SHRPSLTEPCNNHSCPPEWLALDWSECTPSCGPGYRHRVVLCKSGESGDILSESRCPKHGRPTSRVRCNLKRCPPPQ--WIVGPWGEC-SAKCGLGQEMRLVQCLTHTGQ 1035

HSP 4 Score: 73.1738 bits (178), Expect = 2.194e-12
Identity = 63/235 (26.81%), Postives = 92/235 (39.15%), Query Frame = 1 
Query: 3478 WIYSEWSECEGTCEYGSQHRTVLCTDPISEQILPDSKCDIKNKFPNFQKCLLSKLCG-HWIVGKWSQCSASCGLGVKTRTITCNYS---NGSKSIDHSVCKSVAPFEEIHCQVKPCSTNAFWWLVKPSECYEYNCQPGIMYAHVRC-VNRKFQVLYDSKCSRIKHPSYYVGCLNTTCRRYFWTAESWDNIPCPDISCTMKIRNRDVYCVDDYGNIQKDAMCDQSDKPDTWRLCPS 4167
            W Y+ WS C   C  G Q + V+C   +   ++ +  CD K+K    ++   ++ C   W  G WS+CS SC  G++TR + C         K +D S C S  P     C    C     W  +  SEC   +C PG  +  V C       +L +S+C +   P+  V C    C    W    W         C +    R V C+   G  Q    C    +P   + C S
Sbjct:  828 WFYTSWSRCSVLCAGGVQIQQVVCKRLLDHTVVYNHFCDKKSKPKEKRRSCNTEPCSPTWWTGGWSECSRSCNGGLRTREVLCKRRISVTEEKILDDSACSSHRPSLTEPCNNHSCPPE--WLALDWSECTP-SCGPGYRHRVVLCKSGESGDILSESRCPKHGRPTSRVRCNLKRCPPPQWIVGPWGEC---SAKCGLGQEMRLVQCLTHTG--QPSNECLDHQRPAAMQQCRS 1054
[Close]
BLAST of A disintegrin and metalloproteinase with thrombospondin motifs vs. Planmine SMEST
Match: SMESG000038885.1 (SMESG000038885.1)

HSP 1 Score: 3102.77 bits (8043), Expect = 0.000e+0
Identity = 1520/1520 (100.00%), Postives = 1520/1520 (100.00%), Query Frame = 1 
Query:  268 DGVFQWDNKLWFIKPNTKTKFNSKFLKTEMNFLPHKIYFTALNLNKPLFSCKLLKNNGYRNIPQESHFSRVFQRMKRETYPVVDSEIVEPNIIELLIVVTSNFVKRFKKDFRQYILSNVAIATKLLHDPTIKASITXXXXXXXXXXEDYERNNDLHDWSLLSQDRVVSRFCHWVRQKKQLWNYSWDSAILINDGVFSSNAIGIAHLRSMCNDNNCLAVVDRGFGTGFIIAHELAHQMNARHDFDNAEACSFFEKQYDNKTKYNTIMSTSLFFEYYPFIWSVCSQNVINSFLKSKYSFCLKQRNRHRNLYPHEQINEFFQKYSTGVDYDLNEQCSFAFGEKSEFCETDQNSRKKCSVLYCRLKRYPICLRADAIIADGTECDVNQHCINGKCLYKNITIAPIDGGWSEYSEWSNCSRPCNGGVQFSYRTCDNPVPADGGRFCTGTKERIRSCNIEECSSFSDPREESCGKYNLKPYIPTNDEEFPCNLVCITTNHSLKYDISLTDGTPCSPFRSDICVKGTCYKTGCDRIVGSKKAIDNCNICAGQNDTCFKKESFFDGSKVAKVRMIRAFRIPPNVYNLFIKKVSQRMTPFTDEVYDDFELLLVVNRRTVIRRSETIEPLAGGQLRYSGSKNKVETISIKGKLNVGISIVIKVENTKTTLNLPFISYHYFVKDIFVWKYLEVITHPCKDQCGGFIEISPACFKKRDNQRYVDHYCSKATKPEPKIIKCGAICGYRWQRATEHYINSTVNKSCPIRCGTGKVKIPFVCQKINNQDDNNSLWETVEENLCFAVDLVDRPIEELNCVGQCNPLLWSYGKWEECPIECGTTFRYRNFICKDNKGLEWQKEWCERHLGLPDNKETCLSFNNCRNLTRWVTSPWSRCSNSCESELQKRMVYCFRSEKSDEILDEKFLKIHEQISDAFCDIHSPKPITERPCSLNSCYFWIXXXXXXXXXXXXLGFRIQSHECKKKFNKNHEMITVDDKFCLKQNLVKPLDVRMRCFLKKCAIESFWIEMEWSKCSVSCGEGLQYRSLKCGYENENKTLTTWDNNEMCKNKMVPVSIQICKVTPCPKWIYSEWSECEGTCEYGSQHRTVLCTDPISEQILPDSKCDIKNKFPNFQKCLLSKLCGHWIVGKWSQCSASCGLGVKTRTITCNYSNGSKSIDHSVCKSVAPFEEIHCQVKPCSTNAFWWLVKPSECYEYNCQPGIMYAHVRCVNRKFQVLYDSKCSRIKHPSYYVGCLNTTCRRYFWTAESWDNIPCPDISCTMKIRNRDVYCVDDYGNIQKDAMCDQSDKPDTWRLCPSPQNCSNIPRSCKELKSRQSVSKDGEYSLAIDLNWAYFIYCADMNTEEPKEYLTLRELNYARTSKYVSTDVSSCIYEEEMEFNQKCPTCKINENLWSITYYNKIRINLSDLSIDVMDDRFSATNGQSFIPFGTAKDCAGSTSCPKGHFKINLRGTGFSVSMETRWNEVYPKYGYRILRKQTSQIVKGWCGGHCSGCSPLKKFFVEPQMYGRDFEIKSREVL 4827
            DGVFQWDNKLWFIKPNTKTKFNSKFLKTEMNFLPHKIYFTALNLNKPLFSCKLLKNNGYRNIPQESHFSRVFQRMKRETYPVVDSEIVEPNIIELLIVVTSNFVKRFKKDFRQYILSNVAIATKLLHDPTIKASITIDVVDIVLLDEDYERNNDLHDWSLLSQDRVVSRFCHWVRQKKQLWNYSWDSAILINDGVFSSNAIGIAHLRSMCNDNNCLAVVDRGFGTGFIIAHELAHQMNARHDFDNAEACSFFEKQYDNKTKYNTIMSTSLFFEYYPFIWSVCSQNVINSFLKSKYSFCLKQRNRHRNLYPHEQINEFFQKYSTGVDYDLNEQCSFAFGEKSEFCETDQNSRKKCSVLYCRLKRYPICLRADAIIADGTECDVNQHCINGKCLYKNITIAPIDGGWSEYSEWSNCSRPCNGGVQFSYRTCDNPVPADGGRFCTGTKERIRSCNIEECSSFSDPREESCGKYNLKPYIPTNDEEFPCNLVCITTNHSLKYDISLTDGTPCSPFRSDICVKGTCYKTGCDRIVGSKKAIDNCNICAGQNDTCFKKESFFDGSKVAKVRMIRAFRIPPNVYNLFIKKVSQRMTPFTDEVYDDFELLLVVNRRTVIRRSETIEPLAGGQLRYSGSKNKVETISIKGKLNVGISIVIKVENTKTTLNLPFISYHYFVKDIFVWKYLEVITHPCKDQCGGFIEISPACFKKRDNQRYVDHYCSKATKPEPKIIKCGAICGYRWQRATEHYINSTVNKSCPIRCGTGKVKIPFVCQKINNQDDNNSLWETVEENLCFAVDLVDRPIEELNCVGQCNPLLWSYGKWEECPIECGTTFRYRNFICKDNKGLEWQKEWCERHLGLPDNKETCLSFNNCRNLTRWVTSPWSRCSNSCESELQKRMVYCFRSEKSDEILDEKFLKIHEQISDAFCDIHSPKPITERPCSLNSCYFWIKSKSGKCSAKCGLGFRIQSHECKKKFNKNHEMITVDDKFCLKQNLVKPLDVRMRCFLKKCAIESFWIEMEWSKCSVSCGEGLQYRSLKCGYENENKTLTTWDNNEMCKNKMVPVSIQICKVTPCPKWIYSEWSECEGTCEYGSQHRTVLCTDPISEQILPDSKCDIKNKFPNFQKCLLSKLCGHWIVGKWSQCSASCGLGVKTRTITCNYSNGSKSIDHSVCKSVAPFEEIHCQVKPCSTNAFWWLVKPSECYEYNCQPGIMYAHVRCVNRKFQVLYDSKCSRIKHPSYYVGCLNTTCRRYFWTAESWDNIPCPDISCTMKIRNRDVYCVDDYGNIQKDAMCDQSDKPDTWRLCPSPQNCSNIPRSCKELKSRQSVSKDGEYSLAIDLNWAYFIYCADMNTEEPKEYLTLRELNYARTSKYVSTDVSSCIYEEEMEFNQKCPTCKINENLWSITYYNKIRINLSDLSIDVMDDRFSATNGQSFIPFGTAKDCAGSTSCPKGHFKINLRGTGFSVSMETRWNEVYPKYGYRILRKQTSQIVKGWCGGHCSGCSPLKKFFVEPQMYGRDFEIKSREVL
Sbjct:  111 DGVFQWDNKLWFIKPNTKTKFNSKFLKTEMNFLPHKIYFTALNLNKPLFSCKLLKNNGYRNIPQESHFSRVFQRMKRETYPVVDSEIVEPNIIELLIVVTSNFVKRFKKDFRQYILSNVAIATKLLHDPTIKASITIDVVDIVLLDEDYERNNDLHDWSLLSQDRVVSRFCHWVRQKKQLWNYSWDSAILINDGVFSSNAIGIAHLRSMCNDNNCLAVVDRGFGTGFIIAHELAHQMNARHDFDNAEACSFFEKQYDNKTKYNTIMSTSLFFEYYPFIWSVCSQNVINSFLKSKYSFCLKQRNRHRNLYPHEQINEFFQKYSTGVDYDLNEQCSFAFGEKSEFCETDQNSRKKCSVLYCRLKRYPICLRADAIIADGTECDVNQHCINGKCLYKNITIAPIDGGWSEYSEWSNCSRPCNGGVQFSYRTCDNPVPADGGRFCTGTKERIRSCNIEECSSFSDPREESCGKYNLKPYIPTNDEEFPCNLVCITTNHSLKYDISLTDGTPCSPFRSDICVKGTCYKTGCDRIVGSKKAIDNCNICAGQNDTCFKKESFFDGSKVAKVRMIRAFRIPPNVYNLFIKKVSQRMTPFTDEVYDDFELLLVVNRRTVIRRSETIEPLAGGQLRYSGSKNKVETISIKGKLNVGISIVIKVENTKTTLNLPFISYHYFVKDIFVWKYLEVITHPCKDQCGGFIEISPACFKKRDNQRYVDHYCSKATKPEPKIIKCGAICGYRWQRATEHYINSTVNKSCPIRCGTGKVKIPFVCQKINNQDDNNSLWETVEENLCFAVDLVDRPIEELNCVGQCNPLLWSYGKWEECPIECGTTFRYRNFICKDNKGLEWQKEWCERHLGLPDNKETCLSFNNCRNLTRWVTSPWSRCSNSCESELQKRMVYCFRSEKSDEILDEKFLKIHEQISDAFCDIHSPKPITERPCSLNSCYFWIKSKSGKCSAKCGLGFRIQSHECKKKFNKNHEMITVDDKFCLKQNLVKPLDVRMRCFLKKCAIESFWIEMEWSKCSVSCGEGLQYRSLKCGYENENKTLTTWDNNEMCKNKMVPVSIQICKVTPCPKWIYSEWSECEGTCEYGSQHRTVLCTDPISEQILPDSKCDIKNKFPNFQKCLLSKLCGHWIVGKWSQCSASCGLGVKTRTITCNYSNGSKSIDHSVCKSVAPFEEIHCQVKPCSTNAFWWLVKPSECYEYNCQPGIMYAHVRCVNRKFQVLYDSKCSRIKHPSYYVGCLNTTCRRYFWTAESWDNIPCPDISCTMKIRNRDVYCVDDYGNIQKDAMCDQSDKPDTWRLCPSPQNCSNIPRSCKELKSRQSVSKDGEYSLAIDLNWAYFIYCADMNTEEPKEYLTLRELNYARTSKYVSTDVSSCIYEEEMEFNQKCPTCKINENLWSITYYNKIRINLSDLSIDVMDDRFSATNGQSFIPFGTAKDCAGSTSCPKGHFKINLRGTGFSVSMETRWNEVYPKYGYRILRKQTSQIVKGWCGGHCSGCSPLKKFFVEPQMYGRDFEIKSREVL 1630
[Close]
BLAST of A disintegrin and metalloproteinase with thrombospondin motifs vs. Planmine SMEST
Match: SMESG000038885.1 (SMESG000038885.1)

HSP 1 Score: 1679.46 bits (4348), Expect = 0.000e+0
Identity = 819/819 (100.00%), Postives = 819/819 (100.00%), Query Frame = 1 
Query:  268 DGVFQWDNKLWFIKPNTKTKFNSKFLKTEMNFLPHKIYFTALNLNKPLFSCKLLKNNGYRNIPQESHFSRVFQRMKRETYPVVDSEIVEPNIIELLIVVTSNFVKRFKKDFRQYILSNVAIATKLLHDPTIKASITXXXXXXXXXXEDYERNNDLHDWSLLSQDRVVSRFCHWVRQKKQLWNYSWDSAILINDGVFSSNAIGIAHLRSMCNDNNCLAVVDRGFGTGFIIAHELAHQMNARHDFDNAEACSFFEKQYDNKTKYNTIMSTSLFFEYYPFIWSVCSQNVINSFLKSKYSFCLKQRNRHRNLYPHEQINEFFQKYSTGVDYDLNEQCSFAFGEKSEFCETDQNSRKKCSVLYCRLKRYPICLRADAIIADGTECDVNQHCINGKCLYKNITIAPIDGGWSEYSEWSNCSRPCNGGVQFSYRTCDNPVPADGGRFCTGTKERIRSCNIEECSSFSDPREESCGKYNLKPYIPTNDEEFPCNLVCITTNHSLKYDISLTDGTPCSPFRSDICVKGTCYKTGCDRIVGSKKAIDNCNICAGQNDTCFKKESFFDGSKVAKVRMIRAFRIPPNVYNLFIKKVSQRMTPFTDEVYDDFELLLVVNRRTVIRRSETIEPLAGGQLRYSGSKNKVETISIKGKLNVGISIVIKVENTKTTLNLPFISYHYFVKDIFVWKYLEVITHPCKDQCGGFIEISPACFKKRDNQRYVDHYCSKATKPEPKIIKCGAICGYRWQRATEHYINSTVNKSCPIRCGTGKVKIPFVCQKINNQDDNNSLWETVEENLCFAVDLVDRPIEELNCVGQCNPLLWSYGKWEE 2724
            DGVFQWDNKLWFIKPNTKTKFNSKFLKTEMNFLPHKIYFTALNLNKPLFSCKLLKNNGYRNIPQESHFSRVFQRMKRETYPVVDSEIVEPNIIELLIVVTSNFVKRFKKDFRQYILSNVAIATKLLHDPTIKASITIDVVDIVLLDEDYERNNDLHDWSLLSQDRVVSRFCHWVRQKKQLWNYSWDSAILINDGVFSSNAIGIAHLRSMCNDNNCLAVVDRGFGTGFIIAHELAHQMNARHDFDNAEACSFFEKQYDNKTKYNTIMSTSLFFEYYPFIWSVCSQNVINSFLKSKYSFCLKQRNRHRNLYPHEQINEFFQKYSTGVDYDLNEQCSFAFGEKSEFCETDQNSRKKCSVLYCRLKRYPICLRADAIIADGTECDVNQHCINGKCLYKNITIAPIDGGWSEYSEWSNCSRPCNGGVQFSYRTCDNPVPADGGRFCTGTKERIRSCNIEECSSFSDPREESCGKYNLKPYIPTNDEEFPCNLVCITTNHSLKYDISLTDGTPCSPFRSDICVKGTCYKTGCDRIVGSKKAIDNCNICAGQNDTCFKKESFFDGSKVAKVRMIRAFRIPPNVYNLFIKKVSQRMTPFTDEVYDDFELLLVVNRRTVIRRSETIEPLAGGQLRYSGSKNKVETISIKGKLNVGISIVIKVENTKTTLNLPFISYHYFVKDIFVWKYLEVITHPCKDQCGGFIEISPACFKKRDNQRYVDHYCSKATKPEPKIIKCGAICGYRWQRATEHYINSTVNKSCPIRCGTGKVKIPFVCQKINNQDDNNSLWETVEENLCFAVDLVDRPIEELNCVGQCNPLLWSYGKWEE
Sbjct:  111 DGVFQWDNKLWFIKPNTKTKFNSKFLKTEMNFLPHKIYFTALNLNKPLFSCKLLKNNGYRNIPQESHFSRVFQRMKRETYPVVDSEIVEPNIIELLIVVTSNFVKRFKKDFRQYILSNVAIATKLLHDPTIKASITIDVVDIVLLDEDYERNNDLHDWSLLSQDRVVSRFCHWVRQKKQLWNYSWDSAILINDGVFSSNAIGIAHLRSMCNDNNCLAVVDRGFGTGFIIAHELAHQMNARHDFDNAEACSFFEKQYDNKTKYNTIMSTSLFFEYYPFIWSVCSQNVINSFLKSKYSFCLKQRNRHRNLYPHEQINEFFQKYSTGVDYDLNEQCSFAFGEKSEFCETDQNSRKKCSVLYCRLKRYPICLRADAIIADGTECDVNQHCINGKCLYKNITIAPIDGGWSEYSEWSNCSRPCNGGVQFSYRTCDNPVPADGGRFCTGTKERIRSCNIEECSSFSDPREESCGKYNLKPYIPTNDEEFPCNLVCITTNHSLKYDISLTDGTPCSPFRSDICVKGTCYKTGCDRIVGSKKAIDNCNICAGQNDTCFKKESFFDGSKVAKVRMIRAFRIPPNVYNLFIKKVSQRMTPFTDEVYDDFELLLVVNRRTVIRRSETIEPLAGGQLRYSGSKNKVETISIKGKLNVGISIVIKVENTKTTLNLPFISYHYFVKDIFVWKYLEVITHPCKDQCGGFIEISPACFKKRDNQRYVDHYCSKATKPEPKIIKCGAICGYRWQRATEHYINSTVNKSCPIRCGTGKVKIPFVCQKINNQDDNNSLWETVEENLCFAVDLVDRPIEELNCVGQCNPLLWSYGKWEE 929
[Close]
BLAST of A disintegrin and metalloproteinase with thrombospondin motifs vs. Planmine SMEST
Match: SMESG000038885.1 (SMESG000038885.1)

HSP 1 Score: 1272.3 bits (3291), Expect = 0.000e+0
Identity = 628/628 (100.00%), Postives = 628/628 (100.00%), Query Frame = 1 
Query: 2944 MVYCFRSEKSDEILDEKFLKIHEQISDAFCDIHSPKPITERPCSLNSCYFWIXXXXXXXXXXXXLGFRIQSHECKKKFNKNHEMITVDDKFCLKQNLVKPLDVRMRCFLKKCAIESFWIEMEWSKCSVSCGEGLQYRSLKCGYENENKTLTTWDNNEMCKNKMVPVSIQICKVTPCPKWIYSEWSECEGTCEYGSQHRTVLCTDPISEQILPDSKCDIKNKFPNFQKCLLSKLCGHWIVGKWSQCSASCGLGVKTRTITCNYSNGSKSIDHSVCKSVAPFEEIHCQVKPCSTNAFWWLVKPSECYEYNCQPGIMYAHVRCVNRKFQVLYDSKCSRIKHPSYYVGCLNTTCRRYFWTAESWDNIPCPDISCTMKIRNRDVYCVDDYGNIQKDAMCDQSDKPDTWRLCPSPQNCSNIPRSCKELKSRQSVSKDGEYSLAIDLNWAYFIYCADMNTEEPKEYLTLRELNYARTSKYVSTDVSSCIYEEEMEFNQKCPTCKINENLWSITYYNKIRINLSDLSIDVMDDRFSATNGQSFIPFGTAKDCAGSTSCPKGHFKINLRGTGFSVSMETRWNEVYPKYGYRILRKQTSQIVKGWCGGHCSGCSPLKKFFVEPQMYGRDFEIKSREVL 4827
            MVYCFRSEKSDEILDEKFLKIHEQISDAFCDIHSPKPITERPCSLNSCYFWIKSKSGKCSAKCGLGFRIQSHECKKKFNKNHEMITVDDKFCLKQNLVKPLDVRMRCFLKKCAIESFWIEMEWSKCSVSCGEGLQYRSLKCGYENENKTLTTWDNNEMCKNKMVPVSIQICKVTPCPKWIYSEWSECEGTCEYGSQHRTVLCTDPISEQILPDSKCDIKNKFPNFQKCLLSKLCGHWIVGKWSQCSASCGLGVKTRTITCNYSNGSKSIDHSVCKSVAPFEEIHCQVKPCSTNAFWWLVKPSECYEYNCQPGIMYAHVRCVNRKFQVLYDSKCSRIKHPSYYVGCLNTTCRRYFWTAESWDNIPCPDISCTMKIRNRDVYCVDDYGNIQKDAMCDQSDKPDTWRLCPSPQNCSNIPRSCKELKSRQSVSKDGEYSLAIDLNWAYFIYCADMNTEEPKEYLTLRELNYARTSKYVSTDVSSCIYEEEMEFNQKCPTCKINENLWSITYYNKIRINLSDLSIDVMDDRFSATNGQSFIPFGTAKDCAGSTSCPKGHFKINLRGTGFSVSMETRWNEVYPKYGYRILRKQTSQIVKGWCGGHCSGCSPLKKFFVEPQMYGRDFEIKSREVL
Sbjct:    1 MVYCFRSEKSDEILDEKFLKIHEQISDAFCDIHSPKPITERPCSLNSCYFWIKSKSGKCSAKCGLGFRIQSHECKKKFNKNHEMITVDDKFCLKQNLVKPLDVRMRCFLKKCAIESFWIEMEWSKCSVSCGEGLQYRSLKCGYENENKTLTTWDNNEMCKNKMVPVSIQICKVTPCPKWIYSEWSECEGTCEYGSQHRTVLCTDPISEQILPDSKCDIKNKFPNFQKCLLSKLCGHWIVGKWSQCSASCGLGVKTRTITCNYSNGSKSIDHSVCKSVAPFEEIHCQVKPCSTNAFWWLVKPSECYEYNCQPGIMYAHVRCVNRKFQVLYDSKCSRIKHPSYYVGCLNTTCRRYFWTAESWDNIPCPDISCTMKIRNRDVYCVDDYGNIQKDAMCDQSDKPDTWRLCPSPQNCSNIPRSCKELKSRQSVSKDGEYSLAIDLNWAYFIYCADMNTEEPKEYLTLRELNYARTSKYVSTDVSSCIYEEEMEFNQKCPTCKINENLWSITYYNKIRINLSDLSIDVMDDRFSATNGQSFIPFGTAKDCAGSTSCPKGHFKINLRGTGFSVSMETRWNEVYPKYGYRILRKQTSQIVKGWCGGHCSGCSPLKKFFVEPQMYGRDFEIKSREVL 628

HSP 2 Score: 75.485 bits (184), Expect = 2.540e-13
Identity = 100/384 (26.04%), Postives = 169/384 (44.01%), Query Frame = 1 
Query: 2653 RPIEELNC-VGQCNPLLWSYGKWEECPIECGTTFRYRNFIC-----KDNKGLEWQKEWC-ERHLGLPDNKETCLSFNNCRNLTRWVTSPWSRCSNSCESELQKRMVYC-FRSE-KSDEILDEKFLKIHEQISDAFCDIHSPKPITERPCSLNSCYFWIXXXXXXXXXXXXLGFRIQSHECKKKFNKNHEMITVDDKFCLKQNLVKPLDVRMRCFLKKCAIESFWIEMEWSKCSVSCGEGLQYRSLKCGYENENKTLTTWDNNEMCKNKMVPVSIQICKVTPCPK---WIYSEWSEC-EGTCEYGSQHRTVLCTDPISEQILPDSKCDIKNKFPNFQKCLLSKLCGH--WIVGKWSQC---SASCGLGVKTRTITC--NYSNGSK 3744
            +PI E  C +  C    W   K  +C  +CG  FR ++  C     K+++ +    ++C +++L  P +         C   + W+   WS+CS SC   LQ R + C + +E K+    D   +  ++ +           P++ + C +  C  WI S+  +C   C  G + ++  C    +   E I  D K  +K           +C L K  +   WI  +WS+CS SCG G++ R++ C Y N +K++    ++ +CK+ + P     C+V PC     W   + SEC E  C+ G  +  V C +    Q+L DSKC  + K P++    L+  C    W    W        SC + ++ R + C  +Y N  K
Sbjct:   36 KPITERPCSLNSC--YFWIKSKSGKCSAKCGLGFRIQSHECKKKFNKNHEMITVDDKFCLKQNLVKPLDVRMRCFLKKCAIESFWIEMEWSKCSVSCGEGLQYRSLKCGYENENKTLTTWDNNEMCKNKMV-----------PVSIQICKVTPCPKWIYSEWSECEGTCEYGSQHRTVLCTDPIS---EQILPDSKCDIKNKFPN----FQKCLLSK--LCGHWIVGKWSQCSASCGLGVKTRTITCNYSNGSKSI----DHSVCKS-VAPFEEIHCQVKPCSTNAFWWLVKPSECYEYNCQPGIMYAHVRCVNR-KFQVLYDSKCS-RIKHPSYYVGCLNTTCRRYFWTAESWDNIPCPDISCTMKIRNRDVYCVDDYGNIQK 390

HSP 3 Score: 66.6254 bits (161), Expect = 1.351e-10
Identity = 101/394 (25.63%), Postives = 159/394 (40.36%), Query Frame = 1 
Query: 2521 CPIRCGTGKVKIPFVCQKINNQDDNNSLWETVEENLCFAVDLVDRPIEELNC-VGQCN-PLLWSYGKWEECPIECGTTFRYRNFICKDNKGLEWQKEWCERHLGLPDNKETC------LSFNNCRNLT--RWVTSPWSRCSNSCESELQKRMVYCFRSEKSDEILDEKFLKIHEQI-SDAFCDIHSPKPITERPCSLNSCYFWIXXXXXXXXXXXXLGFRIQSHECKKKFNKNHEMITVDDKFCLKQNLVKPLDVRMRCFLKKCAIESFWIEMEWSKC-SVSCGEGLQYRSLKCGYENENKTLTTWDNNEMCKNKMVPVSIQICKVTPCPK--WIYSEWSEC---EGTCEYGSQHRTVLCTDPISEQILPDSKCDIKNKFPNFQKCLLSKLCGH 3651
            C  +CG G       C+K  N+   N    TV++  C   +LV      + C + +C     W   +W +C + CG   +YR+  C    G E +     + L   DN E C      +S   C+     +W+ S WS C  +CE   Q R V C                I EQI  D+ CDI +  P  ++      C  WI  K  +CSA CGLG + ++  C    N ++   ++D   C     V P +  + C +K C+  +FW  ++ S+C   +C  G+ Y  ++C      K    +D+   C     P     C  T C +  W    W      + +C    ++R V C D     I  D+ CD  +K   ++ C   + C +
Sbjct:   59 CSAKCGLGFRIQSHECKKKFNK---NHEMITVDDKFCLKQNLVKPLDVRMRCFLKKCAIESFWIEMEWSKCSVSCGEGLQYRSLKC----GYENE----NKTLTTWDNNEMCKNKMVPVSIQICKVTPCPKWIYSEWSECEGTCEYGSQHRTVLCTDP-------------ISEQILPDSKCDIKNKFPNFQKCLLSKLCGHWIVGKWSQCSASCGLGVKTRTITC----NYSNGSKSIDHSVC---KSVAPFE-EIHCQVKPCSTNAFWWLVKPSECYEYNCQPGIMYAHVRCV---NRKFQVLYDSK--CSRIKHPSYYVGCLNTTCRRYFWTAESWDNIPCPDISCTMKIRNRDVYCVDDYG-NIQKDAMCDQSDKPDTWRLCPSPQNCSN 414
[Close]
BLAST of A disintegrin and metalloproteinase with thrombospondin motifs vs. Planmine SMEST
Match: SMESG000038881.1 (SMESG000038881.1)

HSP 1 Score: 279.641 bits (714), Expect = 6.055e-84
Identity = 131/260 (50.38%), Postives = 190/260 (73.08%), Query Frame = 1 
Query: 4051 CTMKIRNRDVYCVDDYGNIQKDAMCDQSDKPDTWRLCPSPQNCSNIPRSCKELKSRQSVSKDGEYSLAIDLNWAYFIYCADMNTEEPKEYLTLRELNYARTSKYVS-TDVSSCIYEEEMEFNQKCPTCKINENLWSITYYNKIRINLSDLSIDVMDDRFSATNGQSFIPFGTAKDCAGSTSCPKGHFKINLRGTGFSVSMETRWNEVYPKYGYRILRKQTSQIVKGWCGGHCSGCSPLKKFFVEPQMYGRDFEIKSREVL 4827
            C+   + R V CVDD+ N+  +++C++  KP+ W+LC    +CS++PR+CKE+K++   SKDGEY+L ++  W   IYC DM++E P+EYLTL+  NYAR+SK+VS  + +SC Y +E   + +  +   N NL+S T Y+KIRINL D SID++D+ FS T+G +++P+GTAKDC+  T CPKGHFKI+LRGTGFSVS+ET+WNE Y  YGY+I R   SQ++ GWCGG C+GCSP+ K ++ P+  G+D+E KS ++L
Sbjct:   87 CSSVNQKRSVQCVDDFDNVYNESLCNKDSKPNFWKLCQRSTSCSSVPRNCKEIKAKFPDSKDGEYNLEMNSFWNNDIYCYDMDSENPREYLTLKHSNYARSSKFVSLKENASCTYNKEEASHVEIDS---NSNLFSQTNYHKIRINLEDFSIDILDNTFSETSGLAYMPYGTAKDCSDLTICPKGHFKIDLRGTGFSVSVETKWNERYHTYGYKISRTHKSQVILGWCGGRCTGCSPIDKLYIVPKNQGQDYEEKSADLL 343
[Close]
BLAST of A disintegrin and metalloproteinase with thrombospondin motifs vs. Planmine SMEST
Match: SMESG000021248.1 (SMESG000021248.1)

HSP 1 Score: 63.1586 bits (152), Expect = 2.435e-9
Identity = 34/81 (41.98%), Postives = 42/81 (51.85%), Query Frame = 1 
Query: 1393 DGTECDVNQHCINGKCLYKNITIAPIDGGWSEYSEWSNCSRPCNGGVQFSYRTCDNPVPADGGRFCTGTKERIRSCNIEEC 1635
            DG E +V + C  G C        PIDG WS +S+WS CS+ C  G++   R CDNP P  GG  C GT  +   CN   C
Sbjct: 3224 DGKELEV-RACSKGPC--------PIDGRWSSWSKWSYCSKSCGSGIKQKARRCDNPTPKFGGANCVGTNIKKEKCNELPC 3295

HSP 2 Score: 58.5362 bits (140), Expect = 5.270e-8
Identity = 105/384 (27.34%), Postives = 149/384 (38.80%), Query Frame = 1 
Query: 2692 PLLWS-YGKWEECPIECGTTFRYRNFICKDNKGLEWQKEWCERHLGLPDNKETCLSFNNCRNLTRWVTSP---WSRCSNSCESELQKRMVYCFRSEKSDEILDEKFLKIHEQISDAFCDIHSPKPITE-----RP---CSLNSCYFWIXXXXXXXXXXXXLGFRIQSHECKKKFNKNHEMITVDDKFCLKQNLVKPLDVRMRCFLKKCAIESFWIE-MEWSKCSVSCGEGLQYRSLKCGYENENKTLTTWDNNEMCKNKMVPVSIQICKVTPCP---KWI-YSEWSECEGTCEYGSQHRTVLCTDPI-----------SEQILPDSKCDIKNKFPNFQKCLLSK--LCGHWIVGKWSQCSASC-----GLGVKTRTITCNYSNG 3738
            P  WS + +W +C + CG  F  R  +C +        E+    +G    K  CL    C     W  SP   WS CS  C S +++R   C     S+  L +    I E I D  C+ + P PI       +P   CS+ +C F               G + +   C     KN      + KFC      K L+VR  C    C I+  W    +WS CS SCG G++ ++ +C    +N T      N +  N    +  + C   PCP   +W  +  WSEC   C  G Q R   CT+P            S+++    KC       N  KC ++K  +   W   +WS CS  C         +TR   C  SNG
Sbjct: 3068 PGGWSAWQEWSKCSLSCGKGFISRKRLCNNPP----PSEFGMTCIGEDFEKRDCL-LRFCPTDGEW--SPWQEWSICSTKCGSGIRQRTRRCDNPPPSN--LGKPC--IGEAIEDILCEGNLPCPINGAWSEWKPWTVCSI-TCGFG--------------GSQRRDRSCNSPEPKN------NGKFCDG----KELEVRA-CSKGPCPIDGRWSSWSKWSYCSKSCGSGIKQKARRC----DNPTPKFGGANCVGTN----IKKEKCNELPCPVHGQWSNWGSWSECSTECGSGLQERDRTCTEPSPNFGGQWCRGPSKEV---QKC-------NENKCTINKVNIVSPW--SEWSSCSLPCLKNSVDTSERTRNRKCLSSNG 3394

HSP 3 Score: 55.8398 bits (133), Expect = 4.413e-7
Identity = 23/58 (39.66%), Postives = 33/58 (56.90%), Query Frame = 1 
Query: 1465 PIDGGWSEYSEWSNCSRPCNGGVQFSYRTCDNPVPADGGRFCTGTKERIRSCNIEECS 1638
            P+ G WS +  WS CS  C  G+Q   RTC  P P  GG++C G  + ++ CN  +C+
Sbjct: 3296 PVHGQWSNWGSWSECSTECGSGLQERDRTCTEPSPNFGGQWCRGPSKEVQKCNENKCT 3353

HSP 4 Score: 54.299 bits (129), Expect = 1.014e-6
Identity = 24/58 (41.38%), Postives = 36/58 (62.07%), Query Frame = 1 
Query: 1465 PIDGGWSEYSEWSNCSRPCN-GGVQFSYRTCDNPVPADGGRFCTGTKERIRSCNIEEC 1635
            PI+G WSE+  W+ CS  C  GG Q   R+C++P P + G+FC G +  +R+C+   C
Sbjct: 3181 PINGAWSEWKPWTVCSITCGFGGSQRRDRSCNSPEPKNNGKFCDGKELEVRACSKGPC 3238
The following BLAST results are available for this feature:
BLAST of A disintegrin and metalloproteinase with thrombospondin motifs vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ADAMTS202.232e-10226.50ADAM metallopeptidase with thrombospondin type 1 m... [more]
ADAMTS94.244e-10025.09ADAM metallopeptidase with thrombospondin type 1 m... [more]
ADAMTS203.805e-9726.32ADAM metallopeptidase with thrombospondin type 1 m... [more]
ADAMTS201.799e-9626.41ADAM metallopeptidase with thrombospondin type 1 m... [more]
ADAMTS94.717e-9624.57ADAM metallopeptidase with thrombospondin type 1 m... [more]
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BLAST of A disintegrin and metalloproteinase with thrombospondin motifs vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
gon-11.166e-9025.87A disintegrin and metalloproteinase with thrombosp... [more]
gon-12.727e-8725.49A disintegrin and metalloproteinase with thrombosp... [more]
mig-66.653e-3225.39Papilin [Source:UniProtKB/Swiss-Prot;Acc:O76840][more]
mig-66.653e-3225.39Papilin [Source:UniProtKB/Swiss-Prot;Acc:O76840][more]
mig-66.653e-3225.39Papilin [Source:UniProtKB/Swiss-Prot;Acc:O76840][more]
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BLAST of A disintegrin and metalloproteinase with thrombospondin motifs vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
AdamTS-A2.732e-6525.12gene:FBgn0286071 transcript:FBtr0339398[more]
AdamTS-A3.051e-6525.12gene:FBgn0286071 transcript:FBtr0334629[more]
AdamTS-A3.548e-6525.12gene:FBgn0286071 transcript:FBtr0083160[more]
AdamTS-B1.788e-5027.17gene:FBgn0029791 transcript:FBtr0301083[more]
AdamTS-B3.042e-4029.11gene:FBgn0029791 transcript:FBtr0301084[more]
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BLAST of A disintegrin and metalloproteinase with thrombospondin motifs vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
adamts96.500e-10124.66ADAM metallopeptidase with thrombospondin type 1 m... [more]
adamts91.108e-10024.66ADAM metallopeptidase with thrombospondin type 1 m... [more]
adamts63.700e-7027.26ADAM metallopeptidase with thrombospondin type 1 m... [more]
adamts103.116e-6526.77ADAM metallopeptidase with thrombospondin type 1 m... [more]
adamts185.067e-6525.71ADAM metallopeptidase with thrombospondin type 1 m... [more]
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BLAST of A disintegrin and metalloproteinase with thrombospondin motifs vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ADAMTS91.289e-13125.15ADAM metallopeptidase with thrombospondin type 1 m... [more]
ADAMTS91.630e-10725.14ADAM metallopeptidase with thrombospondin type 1 m... [more]
ADAMTS92.807e-10725.14ADAM metallopeptidase with thrombospondin type 1 m... [more]
ADAMTS91.186e-10625.14ADAM metallopeptidase with thrombospondin type 1 m... [more]
ADAMTS92.274e-10624.62ADAM metallopeptidase with thrombospondin type 1 m... [more]
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BLAST of A disintegrin and metalloproteinase with thrombospondin motifs vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Adamts203.279e-10525.05a disintegrin-like and metallopeptidase (reprolysi... [more]
Adamts201.764e-10125.00a disintegrin-like and metallopeptidase (reprolysi... [more]
Adamts91.353e-9925.47a disintegrin-like and metallopeptidase (reprolysi... [more]
Adamts62.422e-7026.17a disintegrin-like and metallopeptidase (reprolysi... [more]
Adamts62.422e-7026.17a disintegrin-like and metallopeptidase (reprolysi... [more]
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BLAST of A disintegrin and metalloproteinase with thrombospondin motifs vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|P59511|ATS20_MOUSE2.294e-10425.05A disintegrin and metalloproteinase with thrombosp... [more]
sp|P59510|ATS20_HUMAN4.222e-10226.77A disintegrin and metalloproteinase with thrombosp... [more]
sp|Q9P2N4|ATS9_HUMAN2.038e-9925.09A disintegrin and metalloproteinase with thrombosp... [more]
sp|Q19791|GON1_CAEEL1.483e-8925.87A disintegrin and metalloproteinase with thrombosp... [more]
sp|Q8TE60|ATS18_HUMAN1.277e-6828.07A disintegrin and metalloproteinase with thrombosp... [more]
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BLAST of A disintegrin and metalloproteinase with thrombospondin motifs vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
T1D1580.000e+049.19ADAMTS5 OS=Dendrocoelum lacteum OX=27895 PE=2 SV=1[more]
A0A4E0RLR30.000e+028.80A disintegrin and metalloproteinase with thrombosp... [more]
G4LXI40.000e+029.24ADAMTS peptidase (M12 family) OS=Schistosoma manso... [more]
A0A5K4F7840.000e+028.25Uncharacterized protein OS=Schistosoma mansoni OX=... [more]
A0A4Z2DIS54.981e-14034.65A disintegrin and metalloproteinase with thrombosp... [more]
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BLAST of A disintegrin and metalloproteinase with thrombospondin motifs vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ADAMTS201.372e-12825.50ADAM metallopeptidase with thrombospondin type 1 m... [more]
adamts99.390e-10325.02ADAM metallopeptidase with thrombospondin type 1 m... [more]
adamts93.731e-9625.45ADAM metallopeptidase with thrombospondin type 1 m... [more]
ADAMTS205.643e-9625.62ADAM metallopeptidase with thrombospondin type 1 m... [more]
ADAMTS201.359e-9524.58ADAM metallopeptidase with thrombospondin type 1 m... [more]
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BLAST of A disintegrin and metalloproteinase with thrombospondin motifs vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ENSPMAT00000009765.11.403e-4524.96pep scaffold:Pmarinus_7.0:GL478392:8852:44628:-1 g... [more]
adamtsl31.566e-3922.96ADAMTS-like 3 [Source:ZFIN;Acc:ZDB-GENE-121030-8][more]
ENSPMAT00000007886.11.022e-3425.97pep scaffold:Pmarinus_7.0:GL477456:619503:639284:-... [more]
ENSPMAT00000007884.14.887e-3425.97pep scaffold:Pmarinus_7.0:GL477456:619446:639227:-... [more]
paplna3.095e-3223.77papilin a, proteoglycan-like sulfated glycoprotein... [more]
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BLAST of A disintegrin and metalloproteinase with thrombospondin motifs vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of A disintegrin and metalloproteinase with thrombospondin motifs vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO443761.421e-10427.66Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO422701.372e-6029.64Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO325163.169e-5924.32Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO471841.286e-4528.13Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO352023.811e-4126.62Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of A disintegrin and metalloproteinase with thrombospondin motifs vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ADAMTS201.592e-10825.59A disintegrin and metalloproteinase with thrombosp... [more]
adamts96.265e-10525.09ADAM metallopeptidase with thrombospondin type 1 m... [more]
ADAMTS208.632e-10226.00A disintegrin and metalloproteinase with thrombosp... [more]
adamts101.863e-7326.62A disintegrin and metalloproteinase with thrombosp... [more]
adamts101.961e-7326.62A disintegrin and metalloproteinase with thrombosp... [more]
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BLAST of A disintegrin and metalloproteinase with thrombospondin motifs vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000038885.10.000e+0100.00SMESG000038885.1[more]
SMESG000038885.10.000e+0100.00SMESG000038885.1[more]
SMESG000038885.12.540e-13100.00SMESG000038885.1[more]
SMESG000038881.16.055e-8450.38SMESG000038881.1[more]
SMESG000021248.12.435e-941.98SMESG000021248.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30027813 ID=SMED30027813|Name=A disintegrin and metalloproteinase with thrombospondin motifs|organism=Schmidtea mediterranea sexual|type=transcript|length=5007bp
TGTATAAATTGCCACTAATTATTGGAAAATGTAATGAATCGATTTTACAC
TTTTTCAAATATATTTTCATTATTAAATCAATGATTTGATTTCAGTTCTT
ACATTTATCAATTGATTTGTGTTGCACGAAATGGTTAAAAGAAATTAAAT
GATGCCAAGGAGAGAGTTCAAAGTGGTGAACATTTGTCTATGACCTTATT
TTGTCAATCATTAATAAGTGTTTTGTTAAACTTTAATCCATTTATATATT
TAGAGTATCACAATTCGGACGGTGTCTTTCAGTGGGATAATAAATTATGG
TTTATAAAACCTAATACAAAGACAAAATTCAATTCTAAATTTTTGAAAAC
TGAAATGAATTTTTTACCTCATAAGATTTATTTTACTGCATTAAATTTAA
ACAAGCCACTTTTCTCATGTAAACTCCTTAAAAATAATGGTTATAGAAAC
ATTCCACAAGAATCTCATTTCAGTCGAGTATTTCAGAGAATGAAAAGAGA
AACATACCCGGTAGTTGACAGTGAGATTGTAGAACCAAATATCATTGAAC
TGTTGATAGTTGTCACTTCGAATTTCGTTAAAAGATTCAAAAAAGATTTT
AGGCAATATATTCTCAGTAATGTGGCCATTGCAACGAAATTATTGCACGA
TCCCACCATAAAAGCATCAATTACAATCGATGTGGTTGACATAGTTCTTT
TGGATGAAGATTATGAGAGAAACAACGATCTTCACGACTGGAGCTTGTTA
AGTCAGGACCGAGTAGTAAGTCGATTTTGTCACTGGGTTCGACAAAAGAA
ACAATTATGGAATTATTCATGGGATTCTGCCATTCTCATAAATGATGGAG
TTTTCAGCAGCAATGCGATCGGCATAGCTCATTTGCGTTCAATGTGCAAT
GACAATAACTGTTTGGCGGTAGTTGATCGTGGTTTCGGAACTGGATTTAT
TATTGCTCATGAACTTGCTCATCAAATGAATGCAAGACATGACTTTGATA
ACGCAGAGGCTTGCAGTTTTTTTGAAAAACAATATGACAATAAAACTAAA
TACAATACAATTATGTCAACAAGTTTATTCTTTGAATATTATCCATTCAT
TTGGTCTGTGTGCAGCCAAAATGTGATAAATTCATTTTTAAAATCGAAAT
ATTCATTTTGCTTAAAGCAAAGAAATCGGCATAGAAATCTCTATCCGCAC
GAACAAATTAATGAATTTTTTCAGAAATACTCCACCGGTGTTGATTATGA
TCTCAATGAACAATGTTCCTTTGCTTTTGGTGAAAAGTCTGAATTTTGTG
AAACGGATCAAAATAGTAGGAAGAAGTGTTCCGTGTTATACTGTCGTTTA
AAGAGATATCCGATTTGTCTAAGGGCTGACGCAATTATTGCTGATGGAAC
TGAATGTGATGTGAACCAGCATTGCATTAATGGGAAATGCTTGTATAAAA
ATATAACAATTGCTCCAATTGATGGAGGGTGGTCAGAGTACAGTGAATGG
TCGAATTGTTCACGGCCGTGCAATGGTGGGGTTCAGTTTTCATACCGGAC
CTGTGATAATCCAGTCCCCGCTGATGGAGGTCGATTCTGTACCGGAACAA
AAGAAAGAATTCGTTCTTGTAATATTGAAGAATGTTCGTCATTTAGTGAT
CCTAGAGAAGAGTCATGCGGCAAATATAACCTTAAGCCATATATACCTAC
AAATGATGAAGAATTTCCTTGCAATTTAGTGTGCATAACAACTAATCATT
CTCTTAAGTATGACATTTCATTAACCGATGGAACGCCATGCAGTCCATTT
CGGTCTGACATCTGTGTTAAAGGAACTTGCTATAAAACTGGTTGTGATCG
AATTGTCGGCTCGAAAAAAGCAATTGATAATTGTAATATTTGTGCTGGAC
AAAATGATACATGTTTCAAAAAAGAGAGTTTTTTCGATGGATCAAAAGTT
GCGAAAGTTCGAATGATAAGGGCTTTTCGAATTCCACCAAATGTCTATAA
TCTTTTCATTAAAAAGGTTTCCCAAAGAATGACTCCATTCACTGATGAAG
TCTATGATGACTTTGAGTTATTGCTCGTTGTAAATAGGCGAACTGTGATA
CGTCGGTCAGAAACAATTGAACCTCTTGCTGGAGGGCAATTGCGTTACAG
TGGGTCTAAGAATAAAGTAGAAACTATTAGTATCAAAGGAAAACTTAATG
TAGGAATTTCAATTGTTATTAAAGTTGAGAATACAAAAACTACTTTGAAT
TTACCTTTTATAAGTTATCATTACTTTGTTAAAGACATTTTTGTTTGGAA
ATATCTGGAAGTAATTACTCATCCATGCAAGGATCAGTGTGGAGGTTTTA
TTGAAATCAGTCCAGCATGTTTTAAGAAGCGAGACAATCAACGATATGTT
GATCATTATTGTTCAAAAGCAACAAAACCAGAACCTAAGATTATTAAATG
CGGTGCAATTTGTGGCTATCGGTGGCAGAGGGCAACAGAGCATTATATTA
ATTCAACAGTCAATAAGTCCTGTCCCATCAGGTGTGGTACTGGGAAAGTT
AAAATTCCATTCGTTTGTCAAAAAATTAATAATCAAGATGATAATAATTC
TTTATGGGAAACTGTAGAAGAAAATCTTTGTTTTGCCGTTGACTTGGTCG
ACAGACCAATTGAAGAACTCAATTGCGTTGGGCAGTGCAATCCGTTATTG
TGGTCTTATGGGAAATGGGAGGAGTGTCCAATTGAATGTGGAACAACTTT
CCGATATCGAAATTTTATTTGTAAAGACAATAAAGGATTAGAGTGGCAAA
AAGAATGGTGTGAACGTCATTTAGGTTTACCGGATAATAAAGAAACTTGC
TTATCATTCAATAACTGTCGCAACTTAACGAGATGGGTAACTTCCCCTTG
GTCTAGGTGTTCTAATTCTTGTGAATCTGAACTGCAAAAGCGCATGGTGT
ACTGTTTTAGATCTGAAAAATCTGATGAAATTTTAGATGAAAAGTTTTTA
AAAATACATGAGCAAATATCTGATGCCTTTTGTGATATACATTCCCCTAA
ACCAATCACCGAAAGGCCATGTTCACTCAACAGCTGTTACTTTTGGATAA
AAAGTAAAAGCGGAAAATGCTCTGCGAAATGTGGCTTGGGTTTTCGAATC
CAGTCTCATGAGTGCAAGAAAAAATTCAATAAAAATCACGAGATGATCAC
AGTTGATGACAAGTTTTGTTTGAAGCAAAATCTCGTCAAACCGTTGGATG
TTAGAATGCGGTGCTTTTTAAAAAAGTGCGCTATCGAATCCTTTTGGATT
GAAATGGAATGGAGTAAATGCTCGGTATCCTGTGGAGAAGGTCTTCAATA
TAGATCTCTTAAATGTGGTTATGAAAATGAGAATAAAACACTTACAACTT
GGGATAATAACGAGATGTGCAAAAATAAAATGGTACCGGTCTCGATACAA
ATATGTAAAGTTACTCCTTGTCCAAAATGGATTTACAGTGAATGGTCTGA
ATGTGAAGGCACCTGTGAATATGGATCACAACATCGAACGGTGCTTTGCA
CAGATCCGATTTCTGAACAAATATTGCCAGATTCAAAATGTGACATAAAA
AATAAATTTCCGAATTTCCAAAAATGTCTTCTATCGAAATTATGTGGTCA
TTGGATAGTTGGTAAATGGTCTCAGTGTTCAGCCTCATGTGGTTTGGGAG
TCAAAACAAGAACGATTACATGTAATTACAGTAACGGTTCTAAGTCAATA
GACCATTCGGTATGCAAAAGCGTGGCTCCGTTTGAAGAAATACATTGCCA
AGTTAAACCATGTTCAACTAATGCATTTTGGTGGCTAGTGAAACCAAGTG
AATGTTACGAATACAATTGTCAGCCTGGAATCATGTATGCTCATGTTAGA
TGTGTAAATAGAAAATTTCAAGTGCTATATGATTCCAAATGCAGTCGAAT
CAAACATCCAAGCTATTATGTTGGATGCCTGAATACTACGTGCCGGCGTT
ATTTCTGGACTGCAGAATCGTGGGATAATATTCCATGCCCTGATATATCA
TGCACGATGAAAATTCGCAATAGAGACGTTTACTGCGTAGATGATTACGG
AAATATTCAAAAGGATGCAATGTGTGATCAATCTGATAAACCAGATACTT
GGAGACTTTGTCCTTCTCCTCAAAATTGTTCAAATATACCTAGAAGTTGC
AAGGAGTTGAAATCCAGACAATCTGTATCAAAAGATGGTGAATACAGCCT
TGCCATTGATTTGAACTGGGCATATTTCATTTATTGTGCCGATATGAATA
CTGAAGAACCAAAGGAATATCTAACTCTGAGGGAACTTAATTATGCTAGG
ACCTCAAAATATGTATCAACAGATGTGTCAAGTTGTATTTATGAAGAAGA
AATGGAATTCAATCAAAAGTGTCCAACTTGTAAGATCAATGAGAACTTAT
GGAGCATCACTTACTACAACAAAATTAGAATTAATTTATCCGATCTTTCA
ATTGACGTAATGGATGACCGCTTTTCTGCGACTAATGGTCAGTCCTTCAT
CCCATTCGGAACTGCGAAGGACTGTGCAGGTTCAACTAGTTGTCCGAAAG
GTCATTTCAAAATAAATTTAAGAGGGACTGGATTTTCAGTTTCAATGGAA
ACAAGGTGGAACGAGGTATATCCAAAATATGGTTACCGAATTTTGAGAAA
GCAGACATCCCAAATTGTTAAAGGTTGGTGTGGCGGTCATTGTTCAGGGT
GTTCTCCGTTGAAAAAATTCTTTGTAGAGCCACAAATGTATGGTCGAGAC
TTTGAAATCAAGTCCAGAGAAGTCCTATAAAACTACTTGTAAAAATAGAC
ATTCAAATCCAAAGAGTTGAAAATTATTTGAACTGTTTTTTTTCTTATCA
AACTTTTTAGCACATATTTTAATTTATTTTTGCTCATTTATTTTAATATG
AGCTCGATTTTTTATGAAATTTTTGGTAGTGCAATTATTGCTAATATCTA
GCTTGAT
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protein sequence of SMED30027813-orf-1

>SMED30027813-orf-1 ID=SMED30027813-orf-1|Name=SMED30027813-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=1547bp
MTLFCQSLISVLLNFNPFIYLEYHNSDGVFQWDNKLWFIKPNTKTKFNSK
FLKTEMNFLPHKIYFTALNLNKPLFSCKLLKNNGYRNIPQESHFSRVFQR
MKRETYPVVDSEIVEPNIIELLIVVTSNFVKRFKKDFRQYILSNVAIATK
LLHDPTIKASITIDVVDIVLLDEDYERNNDLHDWSLLSQDRVVSRFCHWV
RQKKQLWNYSWDSAILINDGVFSSNAIGIAHLRSMCNDNNCLAVVDRGFG
TGFIIAHELAHQMNARHDFDNAEACSFFEKQYDNKTKYNTIMSTSLFFEY
YPFIWSVCSQNVINSFLKSKYSFCLKQRNRHRNLYPHEQINEFFQKYSTG
VDYDLNEQCSFAFGEKSEFCETDQNSRKKCSVLYCRLKRYPICLRADAII
ADGTECDVNQHCINGKCLYKNITIAPIDGGWSEYSEWSNCSRPCNGGVQF
SYRTCDNPVPADGGRFCTGTKERIRSCNIEECSSFSDPREESCGKYNLKP
YIPTNDEEFPCNLVCITTNHSLKYDISLTDGTPCSPFRSDICVKGTCYKT
GCDRIVGSKKAIDNCNICAGQNDTCFKKESFFDGSKVAKVRMIRAFRIPP
NVYNLFIKKVSQRMTPFTDEVYDDFELLLVVNRRTVIRRSETIEPLAGGQ
LRYSGSKNKVETISIKGKLNVGISIVIKVENTKTTLNLPFISYHYFVKDI
FVWKYLEVITHPCKDQCGGFIEISPACFKKRDNQRYVDHYCSKATKPEPK
IIKCGAICGYRWQRATEHYINSTVNKSCPIRCGTGKVKIPFVCQKINNQD
DNNSLWETVEENLCFAVDLVDRPIEELNCVGQCNPLLWSYGKWEECPIEC
GTTFRYRNFICKDNKGLEWQKEWCERHLGLPDNKETCLSFNNCRNLTRWV
TSPWSRCSNSCESELQKRMVYCFRSEKSDEILDEKFLKIHEQISDAFCDI
HSPKPITERPCSLNSCYFWIKSKSGKCSAKCGLGFRIQSHECKKKFNKNH
EMITVDDKFCLKQNLVKPLDVRMRCFLKKCAIESFWIEMEWSKCSVSCGE
GLQYRSLKCGYENENKTLTTWDNNEMCKNKMVPVSIQICKVTPCPKWIYS
EWSECEGTCEYGSQHRTVLCTDPISEQILPDSKCDIKNKFPNFQKCLLSK
LCGHWIVGKWSQCSASCGLGVKTRTITCNYSNGSKSIDHSVCKSVAPFEE
IHCQVKPCSTNAFWWLVKPSECYEYNCQPGIMYAHVRCVNRKFQVLYDSK
CSRIKHPSYYVGCLNTTCRRYFWTAESWDNIPCPDISCTMKIRNRDVYCV
DDYGNIQKDAMCDQSDKPDTWRLCPSPQNCSNIPRSCKELKSRQSVSKDG
EYSLAIDLNWAYFIYCADMNTEEPKEYLTLRELNYARTSKYVSTDVSSCI
YEEEMEFNQKCPTCKINENLWSITYYNKIRINLSDLSIDVMDDRFSATNG
QSFIPFGTAKDCAGSTSCPKGHFKINLRGTGFSVSMETRWNEVYPKYGYR
ILRKQTSQIVKGWCGGHCSGCSPLKKFFVEPQMYGRDFEIKSREVL*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000020protonephridia
PLANA:0000036eye
PLANA:0000101muscle cell
PLANA:0000105secretory cell
PLANA:0002142parenchyma
PLANA:0003001lateral region of the whole animal
Vocabulary: INTERPRO
TermDefinition
IPR041645ADAM_CR_2
IPR036383TSP1_rpt_sf
IPR013273ADAMTS/ADAMTS-like
IPR000884TSP1_rpt
IPR006586ADAM_Cys-rich
IPR024079MetalloPept_cat_dom_sf
IPR012314Pept_M12B_GON-ADAMTSs
IPR001590Peptidase_M12B
Vocabulary: cellular component
TermDefinition
GO:0005578proteinaceous extracellular matrix
Vocabulary: molecular function
TermDefinition
GO:0008237metallopeptidase activity
GO:0008270zinc ion binding
GO:0004222metalloendopeptidase activity
GO:0046872metal ion binding
Vocabulary: biological process
TermDefinition
GO:0006508proteolysis
GO:0007229integrin-mediated signaling pathway
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR013273ADAMTS/ADAMTS-likePRINTSPR01857ADAMTSFAMILYcoord: 556..575
score: 42.35
coord: 437..455
score: 54.99
coord: 536..555
score: 42.14
IPR000884Thrombospondin type-1 (TSP1) repeatSMARTSM00209TSP1_2coord: 898..967
e-value: 0.67
score: 10.9
coord: 1154..1209
e-value: 3.9E-7
score: 39.7
coord: 1096..1147
e-value: 0.0016
score: 27.7
coord: 1036..1095
e-value: 0.0031
score: 26.8
coord: 837..894
e-value: 3.5
score: 4.5
coord: 431..483
e-value: 8.6E-12
score: 55.2
IPR000884Thrombospondin type-1 (TSP1) repeatPFAMPF00090TSP_1coord: 1158..1182
e-value: 4.8E-4
score: 20.3
coord: 1100..1152
e-value: 1.4E-4
score: 22.0
coord: 1040..1094
e-value: 1.2E-4
score: 22.2
coord: 432..482
e-value: 5.8E-10
score: 39.2
coord: 901..924
e-value: 0.082
score: 13.1
IPR000884Thrombospondin type-1 (TSP1) repeatPROSITEPS50092TSP1coord: 1030..1095
score: 8.873
IPR000884Thrombospondin type-1 (TSP1) repeatPROSITEPS50092TSP1coord: 428..483
score: 12.878
IPR000884Thrombospondin type-1 (TSP1) repeatPROSITEPS50092TSP1coord: 895..967
score: 8.729
IPR000884Thrombospondin type-1 (TSP1) repeatPROSITEPS50092TSP1coord: 1151..1209
score: 10.365
IPR006586ADAM, cysteine-rich domainSMARTSM00608acrcoord: 351..420
e-value: 0.0042
score: -15.6
NoneNo IPR availablePFAMPF13688Reprolysin_5coord: 117..295
e-value: 1.8E-14
score: 54.3
NoneNo IPR availableGENE3DG3DSA:2.60.120.830coord: 561..705
e-value: 3.1E-7
score: 32.4
NoneNo IPR availablePANTHERPTHR13723ADAMTS A DISINTEGRIN AND METALLOPROTEASE WITH THROMBOSPONDIN MOTIFS PROTEASEcoord: 119..1002
NoneNo IPR availablePANTHERPTHR13723ADAMTS A DISINTEGRIN AND METALLOPROTEASE WITH THROMBOSPONDIN MOTIFS PROTEASEcoord: 1022..1211
NoneNo IPR availablePANTHERPTHR13723:SF278ADAM METALLOPEPTIDASE WITH THROMBOSPONDIN TYPE 1 MOTIF A, ISOFORM Bcoord: 1022..1211
NoneNo IPR availablePANTHERPTHR13723:SF278ADAM METALLOPEPTIDASE WITH THROMBOSPONDIN TYPE 1 MOTIF A, ISOFORM Bcoord: 119..1002
coord: 1226..1523
NoneNo IPR availablePANTHERPTHR13723ADAMTS A DISINTEGRIN AND METALLOPROTEASE WITH THROMBOSPONDIN MOTIFS PROTEASEcoord: 1226..1523
NoneNo IPR availableSUPERFAMILYSSF55486Metalloproteases ("zincins"), catalytic domaincoord: 115..326
IPR041645ADAM cysteine-rich domain 2PFAMPF17771ADAM_CR_2coord: 350..418
e-value: 3.1E-14
score: 53.3
IPR036383Thrombospondin type-1 (TSP1) repeat superfamilyGENE3DG3DSA:2.20.100.10coord: 426..482
e-value: 1.5E-17
score: 65.7
IPR036383Thrombospondin type-1 (TSP1) repeat superfamilyGENE3DG3DSA:2.20.100.10coord: 895..966
e-value: 1.1E-5
score: 27.8
coord: 1096..1150
e-value: 4.5E-6
score: 29.0
coord: 1034..1095
e-value: 2.1E-8
score: 36.5
coord: 1151..1208
e-value: 1.7E-8
score: 36.8
IPR036383Thrombospondin type-1 (TSP1) repeat superfamilySUPERFAMILYSSF82895TSP-1 type 1 repeatcoord: 1036..1094
IPR036383Thrombospondin type-1 (TSP1) repeat superfamilySUPERFAMILYSSF82895TSP-1 type 1 repeatcoord: 425..482
IPR036383Thrombospondin type-1 (TSP1) repeat superfamilySUPERFAMILYSSF82895TSP-1 type 1 repeatcoord: 1152..1208
IPR036383Thrombospondin type-1 (TSP1) repeat superfamilySUPERFAMILYSSF82895TSP-1 type 1 repeatcoord: 897..966
IPR036383Thrombospondin type-1 (TSP1) repeat superfamilySUPERFAMILYSSF82895TSP-1 type 1 repeatcoord: 1089..1148
IPR012314Peptidase M12B, GON-ADAMTSsPFAMPF08685GONcoord: 1334..1525
e-value: 6.1E-50
score: 169.9
IPR012314Peptidase M12B, GON-ADAMTSsPROSITEPS51046GONcoord: 1333..1534
score: 43.752
IPR024079Metallopeptidase, catalytic domain superfamilyGENE3DG3DSA:3.40.390.10coord: 113..333
e-value: 2.7E-42
score: 146.9
IPR001590Peptidase M12B, ADAM/reprolysinPROSITEPS50215ADAM_MEPROcoord: 117..329
score: 14.689