Cullin 3

Overview
NameCullin 3
Smed IDSMED30027794
Length (bp)1622
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Cullin 3 (SMED30027794) t-SNE clustered cells

Violin plots show distribution of expression levels for Cullin 3 (SMED30027794) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Cullin 3 (SMED30027794) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Cullin 3 (SMED30027794) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30027794

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 7

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
Smed sexual biotypeSMED30027794h1SMcG0002989 Contig14510newmark_estsPMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30027794h1SMcG0002989 Contig14510uc_Smed_v2PMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30027794h1SMcG0002989 Contig50394newmark_estsPMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30027794h1SMcG0002989 Contig50394uc_Smed_v2PMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
neuronSMED30027794h1SMcG0002989 Contig18900newmark_estsPMID:27612384
Roberts-Galbraith et al., 2016		whole organism asexual adult colorimetric in situ hybridization evidence
neuronSMED30027794h1SMcG0002989 Contig18900uc_Smed_v2PMID:27612384
Roberts-Galbraith et al., 2016		whole organism asexual adult colorimetric in situ hybridization evidence
whole organismSMED30027794h1SMcG0002989 HO005153smed_ncbi_20240424PMID:29291974
Strand et al., 2018		whole organism asexual adult colorimetric in situ hybridization evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Cullin 3 vs. Ensembl Human
Match: CUL3 (cullin 3 [Source:HGNC Symbol;Acc:HGNC:2553])

HSP 1 Score: 595.89 bits (1535), Expect = 0.000e+0
Identity = 294/526 (55.89%), Postives = 388/526 (73.76%), Query Frame = 1 
Query:   52 SSNPSKMRIKAFPTSMSDQSVSKIWECLKRAIIEIQKKNNSGLSFEELYRNAYTMVLQKNGEQLYNGTKAVVTDHMI-KIRDEVLERLTNNFLAFLNRCWKDHITAMVMIRDILMYMDRVYVTTTDKPNVYNTGMIIFRDTVLRHEAIRRHLRVTLLDMVKRERHGEVISRLQLRDACQMLAQLGVDKLNIYEEDFENYFLEQSRDFYRSESERLLTENASNLYITQVNKIIEDEAKRARDFLNSTTEAKIVQVLNEELIKNHIESVVNTENFGLTHMLSNKKYSEIALMFNLLKRVDNGLATMCSCISRFLREEGRKIVEDD---KTPQIYIQELIYXXXXXXXXXXXXXXXXQLFKNQINSDFEFFINQNSRSPEYLSLYIDDKLKRGTKGISDQDIDAIFDKCIILFRYLQDKDIFERYYKQHLAKRLLMSKSQSDDQEKSMISKLLIECGGVFTSKLEGMFKDMAISKTLMEEFHSQLQMYTTNTLGIDLFVRVLTTGLWPTQTATQTVCMPDEAQNAFSIY 1617
            S   +KMRI+AFP +M ++ V+ IW+ LK AI EIQ+KNNSGLSFEELYRNAYTMVL K+GE+LY G + VVT+H+I K+R++VL  L NNFL  LN+ W DH TAMVMIRDILMYMDRVYV   +  NVYN G+IIFRD V+R+  IR HLR TLLDM+ RER GEV+ R  +R+ACQML  LG++  ++YEEDFE  FLE S +F++ ES++ L EN++++YI +V   I +E +R    L+ +TE  IV+V+  ELI  H++++V  EN GL HML N K  ++  M+ L  RV NGL TMC C+S +LRE+G+ +V ++   K P  YIQ L+ L+ R +  LL +  N++LFK  I  DFE+F+N NSRSPEYLSL+IDDKLK+G KG+++Q+++ I DK ++LFR++Q+KD+FERYYKQHLA+RLL +KS SDD EK+MISKL  ECG  FTSKLEGMF+DM+IS T M+EF   LQ    +  G+DL VRVLTTG WPTQ+AT    +P   ++AF I+
Sbjct:   10 SRKDTKMRIRAFPMTMDEKYVNSIWDLLKNAIQEIQRKNNSGLSFEELYRNAYTMVLHKHGEKLYTGLREVVTEHLINKVREDVLNSLNNNFLQTLNQAWNDHQTAMVMIRDILMYMDRVYVQQNNVENVYNLGLIIFRDQVVRYGCIRDHLRQTLLDMIARERKGEVVDRGAIRNACQMLMILGLEGRSVYEEDFEAPFLEMSAEFFQMESQKFLAENSASVYIKKVEARINEEIERVMHCLDKSTEEPIVKVVERELISKHMKTIVEMENSGLVHMLKNGKTEDLGCMYKLFSRVPNGLKTMCECMSSYLREQGKALVSEEGEGKNPVDYIQGLLDLKSRFDRFLLESFNNDRLFKQTIAGDFEYFLNLNSRSPEYLSLFIDDKLKKGVKGLTEQEVETILDKAMVLFRFMQEKDVFERYYKQHLARRLLTNKSVSDDSEKNMISKLKTECGCQFTSKLEGMFRDMSISNTTMDEFRQHLQATGVSLGGVDLTVRVLTTGYWPTQSATPKCNIPPAPRHAFEIF 535
[Close]
BLAST of Cullin 3 vs. Ensembl Human
Match: CUL3 (cullin 3 [Source:HGNC Symbol;Acc:HGNC:2553])

HSP 1 Score: 578.17 bits (1489), Expect = 0.000e+0
Identity = 286/511 (55.97%), Postives = 377/511 (73.78%), Query Frame = 1 
Query:   97 MSDQSVSKIWECLKRAIIEIQKKNNSGLSFEELYRNAYTMVLQKNGEQLYNGTKAVVTDHMI-KIRDEVLERLTNNFLAFLNRCWKDHITAMVMIRDILMYMDRVYVTTTDKPNVYNTGMIIFRDTVLRHEAIRRHLRVTLLDMVKRERHGEVISRLQLRDACQMLAQLGVDKLNIYEEDFENYFLEQSRDFYRSESERLLTENASNLYITQVNKIIEDEAKRARDFLNSTTEAKIVQVLNEELIKNHIESVVNTENFGLTHMLSNKKYSEIALMFNLLKRVDNGLATMCSCISRFLREEGRKIVEDD---KTPQIYIQELIYXXXXXXXXXXXXXXXXQLFKNQINSDFEFFINQNSRSPEYLSLYIDDKLKRGTKGISDQDIDAIFDKCIILFRYLQDKDIFERYYKQHLAKRLLMSKSQSDDQEKSMISKLLIECGGVFTSKLEGMFKDMAISKTLMEEFHSQLQMYTTNTLGIDLFVRVLTTGLWPTQTATQTVCMPDEAQNAFSIY 1617
            M ++ V+ IW+ LK AI EIQ+KNNSGLSFEELYRNAYTMVL K+GE+LY G + VVT+H+I K+R++VL  L NNFL  LN+ W DH TAMVMIRDILMYMDRVYV   +  NVYN G+IIFRD V+R+  IR HLR TLLDM+ RER GEV+ R  +R+ACQML  LG++  ++YEEDFE  FLE S +F++ ES++ L EN++++YI +V   I +E +R    L+ +TE  IV+V+  ELI  H++++V  EN GL HML N K  ++  M+ L  RV NGL TMC C+S +LRE+G+ +V ++   K P  YIQ L+ L+ R +  LL +  N++LFK  I  DFE+F+N NSRSPEYLSL+IDDKLK+G KG+++Q+++ I DK ++LFR++Q+KD+FERYYKQHLA+RLL +KS SDD EK+MISKL  ECG  FTSKLEGMF+DM+IS T M+EF   LQ    +  G+DL VRVLTTG WPTQ+AT    +P   ++AF I+
Sbjct:    1 MDEKYVNSIWDLLKNAIQEIQRKNNSGLSFEELYRNAYTMVLHKHGEKLYTGLREVVTEHLINKVREDVLNSLNNNFLQTLNQAWNDHQTAMVMIRDILMYMDRVYVQQNNVENVYNLGLIIFRDQVVRYGCIRDHLRQTLLDMIARERKGEVVDRGAIRNACQMLMILGLEGRSVYEEDFEAPFLEMSAEFFQMESQKFLAENSASVYIKKVEARINEEIERVMHCLDKSTEEPIVKVVERELISKHMKTIVEMENSGLVHMLKNGKTEDLGCMYKLFSRVPNGLKTMCECMSSYLREQGKALVSEEGEGKNPVDYIQGLLDLKSRFDRFLLESFNNDRLFKQTIAGDFEYFLNLNSRSPEYLSLFIDDKLKKGVKGLTEQEVETILDKAMVLFRFMQEKDVFERYYKQHLARRLLTNKSVSDDSEKNMISKLKTECGCQFTSKLEGMFRDMSISNTTMDEFRQHLQATGVSLGGVDLTVRVLTTGYWPTQSATPKCNIPPAPRHAFEIF 511
[Close]
BLAST of Cullin 3 vs. Ensembl Human
Match: CUL3 (cullin 3 [Source:HGNC Symbol;Acc:HGNC:2553])

HSP 1 Score: 578.17 bits (1489), Expect = 0.000e+0
Identity = 286/511 (55.97%), Postives = 377/511 (73.78%), Query Frame = 1 
Query:   97 MSDQSVSKIWECLKRAIIEIQKKNNSGLSFEELYRNAYTMVLQKNGEQLYNGTKAVVTDHMI-KIRDEVLERLTNNFLAFLNRCWKDHITAMVMIRDILMYMDRVYVTTTDKPNVYNTGMIIFRDTVLRHEAIRRHLRVTLLDMVKRERHGEVISRLQLRDACQMLAQLGVDKLNIYEEDFENYFLEQSRDFYRSESERLLTENASNLYITQVNKIIEDEAKRARDFLNSTTEAKIVQVLNEELIKNHIESVVNTENFGLTHMLSNKKYSEIALMFNLLKRVDNGLATMCSCISRFLREEGRKIVEDD---KTPQIYIQELIYXXXXXXXXXXXXXXXXQLFKNQINSDFEFFINQNSRSPEYLSLYIDDKLKRGTKGISDQDIDAIFDKCIILFRYLQDKDIFERYYKQHLAKRLLMSKSQSDDQEKSMISKLLIECGGVFTSKLEGMFKDMAISKTLMEEFHSQLQMYTTNTLGIDLFVRVLTTGLWPTQTATQTVCMPDEAQNAFSIY 1617
            M ++ V+ IW+ LK AI EIQ+KNNSGLSFEELYRNAYTMVL K+GE+LY G + VVT+H+I K+R++VL  L NNFL  LN+ W DH TAMVMIRDILMYMDRVYV   +  NVYN G+IIFRD V+R+  IR HLR TLLDM+ RER GEV+ R  +R+ACQML  LG++  ++YEEDFE  FLE S +F++ ES++ L EN++++YI +V   I +E +R    L+ +TE  IV+V+  ELI  H++++V  EN GL HML N K  ++  M+ L  RV NGL TMC C+S +LRE+G+ +V ++   K P  YIQ L+ L+ R +  LL +  N++LFK  I  DFE+F+N NSRSPEYLSL+IDDKLK+G KG+++Q+++ I DK ++LFR++Q+KD+FERYYKQHLA+RLL +KS SDD EK+MISKL  ECG  FTSKLEGMF+DM+IS T M+EF   LQ    +  G+DL VRVLTTG WPTQ+AT    +P   ++AF I+
Sbjct:    1 MDEKYVNSIWDLLKNAIQEIQRKNNSGLSFEELYRNAYTMVLHKHGEKLYTGLREVVTEHLINKVREDVLNSLNNNFLQTLNQAWNDHQTAMVMIRDILMYMDRVYVQQNNVENVYNLGLIIFRDQVVRYGCIRDHLRQTLLDMIARERKGEVVDRGAIRNACQMLMILGLEGRSVYEEDFEAPFLEMSAEFFQMESQKFLAENSASVYIKKVEARINEEIERVMHCLDKSTEEPIVKVVERELISKHMKTIVEMENSGLVHMLKNGKTEDLGCMYKLFSRVPNGLKTMCECMSSYLREQGKALVSEEGEGKNPVDYIQGLLDLKSRFDRFLLESFNNDRLFKQTIAGDFEYFLNLNSRSPEYLSLFIDDKLKKGVKGLTEQEVETILDKAMVLFRFMQEKDVFERYYKQHLARRLLTNKSVSDDSEKNMISKLKTECGCQFTSKLEGMFRDMSISNTTMDEFRQHLQATGVSLGGVDLTVRVLTTGYWPTQSATPKCNIPPAPRHAFEIF 511
[Close]
BLAST of Cullin 3 vs. Ensembl Human
Match: CUL3 (cullin 3 [Source:HGNC Symbol;Acc:HGNC:2553])

HSP 1 Score: 493.426 bits (1269), Expect = 9.285e-168
Identity = 243/447 (54.36%), Postives = 324/447 (72.48%), Query Frame = 1 
Query:  286 IRDEVLERLTNNFLAFLNRCWKDHITAMVMIRDILMYMDRVYVTTTDKPNVYNTGMIIFRDTVLRHEAIRRHLRVTLLDMVKRERHGEVISRLQLRDACQMLAQLGVDKLNIYEEDFENYFLEQSRDFYRSESERLLTENASNLYITQVNKIIEDEAKRARDFLNSTTEAKIVQVLNEELIKNHIESVVNTENFGLTHMLSNKKYSEIALMFNLLKRVDNGLATMCSCISRFLREEGRKIVEDD---KTPQIYIQELIYXXXXXXXXXXXXXXXXQLFKNQINSDFEFFINQNSRSPEYLSLYIDDKLKRGTKGISDQDIDAIFDKCIILFRYLQDKDIFERYYKQHLAKRLLMSKSQSDDQEKSMISKLLIECGGVFTSKLEGMFKDMAISKTLMEEFHSQLQMYTTNTLGIDLFVRVLTTGLWPTQTATQTVCMPDEAQNAFSIY 1617
            +R++VL  L NNFL  LN+ W DH TAMVMIRDILMYMDRVYV   +  NVYN G+IIFRD V+R+  IR HLR TLLDM+ RER GEV+ R  +R+ACQML  LG++  ++YEEDFE  FLE S +F++ ES++ L EN++++YI +V   I +E +R    L+ +TE  IV+V+  ELI  H++++V  EN GL HML N K  ++  M+ L  RV NGL TMC C+S +LRE+G+ +V ++   K P  YIQ L+ L+ R +  LL +  N++LFK  I  DFE+F+N NSRSPEYLSL+IDDKLK+G KG+++Q+++ I DK ++LFR++Q+KD+FERYYKQHLA+RLL +KS SDD EK+MISKL  ECG  FTSKLEGMF+DM+IS T M+EF   LQ    +  G+DL VRVLTTG WPTQ+AT    +P   ++AF I+
Sbjct:   23 VREDVLNSLNNNFLQTLNQAWNDHQTAMVMIRDILMYMDRVYVQQNNVENVYNLGLIIFRDQVVRYGCIRDHLRQTLLDMIARERKGEVVDRGAIRNACQMLMILGLEGRSVYEEDFEAPFLEMSAEFFQMESQKFLAENSASVYIKKVEARINEEIERVMHCLDKSTEEPIVKVVERELISKHMKTIVEMENSGLVHMLKNGKTEDLGCMYKLFSRVPNGLKTMCECMSSYLREQGKALVSEEGEGKNPVDYIQGLLDLKSRFDRFLLESFNNDRLFKQTIAGDFEYFLNLNSRSPEYLSLFIDDKLKKGVKGLTEQEVETILDKAMVLFRFMQEKDVFERYYKQHLARRLLTNKSVSDDSEKNMISKLKTECGCQFTSKLEGMFRDMSISNTTMDEFRQHLQATGVSLGGVDLTVRVLTTGYWPTQSATPKCNIPPAPRHAFEIF 469
[Close]
BLAST of Cullin 3 vs. Ensembl Human
Match: CUL4A (cullin 4A [Source:HGNC Symbol;Acc:HGNC:2554])

HSP 1 Score: 284.648 bits (727), Expect = 1.800e-86
Identity = 167/516 (32.36%), Postives = 281/516 (54.46%), Query Frame = 1 
Query:   67 KMRIKAFP--TSMSDQSVSKIWECLKRAIIEIQKKNNSGLSFEELYRNAYTMVLQKNGEQLYNGTKAVVTDH----MIKIRDEVLERLTNNFLAFLNRCWKDHITAMVMIRDILMYMDRVYVTTTDK-PNVYNTGMIIFRDTVLRHEAIRRHLRVTLLDMVKRERHGEVISRLQLRDACQMLAQLGVDKLNIYEEDFENYFLEQSRDFYRSESERLLTENASNLYITQVNKIIEDEAKRARDFLNSTTEAKIVQVLNEELIKNHIESVVNTENFGLTHMLSNKKYSEIALMFNLLKRVDNGLATMCSCISRFLREEGRKIVEDDKTPQIYIQELIYXXXXXXXXXXXXXXXXQLFKNQINSDFEFFINQNSRSP-EYLSLYIDDKLKRGTKGISDQDIDAIFDKCIILFRYLQDKDIFERYYKQHLAKRLLMSKSQSDDQEKSMISKLLIECGGVFTSKLEGMFKDMAISKTLMEEFHSQLQMYTTNTLGIDLFVRVLTTGLWPTQTATQTVCMPD 1590
            K+ IK F     + D      W  L  A+  +Q   +   + EELY+    +   K    LY   +    DH    ++  R++ L+ +   FL  +N CW+DH   M+MIR I +++DR YV      P++++ G+ +FR  ++  + ++      +L +++RER GE + R  LR    ML+ L      +Y++ FE  FLE++   Y +E +RL+ E     Y+  V+K +E+E  R   +L+ +T+  ++  + ++L+  H+ +++     GL H+L   +  ++A M+ L  RV  G   +    S +++  G  IV + +  +  +Q+L+  +D+ + ++      N+ F N +   FE FIN+    P E ++ ++D KL+ G K  +D++++   DK +ILFR++  KD+FE +YK+ LAKRLL+ KS S D EKSM+SKL  ECG  FTSKLEGMFKDM +SK +M  F   +Q   +++  IDL V +LT G WPT T  +    P+
Sbjct:   42 KLVIKNFRDRPRLPDNYTQDTWRKLHEAVRAVQSSTSIRYNLEELYQAVENLCSHKVSPMLYKQLRQACEDHVQAQILPFREDSLDSVL--FLKKINTCWQDHCRQMIMIRSIFLFLDRTYVLQNSTLPSIWDMGLELFRTHIISDKMVQSKTIDGILLLIERERSGEAVDRSLLRSLLGMLSDL-----QVYKDSFELKFLEETNCLYAAEGQRLMQEREVPEYLNHVSKRLEEEGDRVITYLDHSTQKPLIACVEKQLLGEHLTAILQK---GLDHLLDENRVPDLAQMYQLFSRVRGGQQALLQHWSEYIKTFGTAIVINPEKDKDMVQDLLDFKDKVDHVIEVCFQKNERFVNLMKESFETFINKRPNKPAELIAKHVDSKLRAGNKEATDEELERTLDKIMILFRFIHGKDVFEAFYKKDLAKRLLVGKSASVDAEKSMLSKLKHECGAAFTSKLEGMFKDMELSKDIMVHFKQHMQ-NQSDSGPIDLTVNILTMGYWPTYTPMEVHLTPE 546
[Close]
BLAST of Cullin 3 vs. Ensembl Celegans
Match: cul-3 (Cullin-3 [Source:UniProtKB/Swiss-Prot;Acc:Q17391])

HSP 1 Score: 431.409 bits (1108), Expect = 4.278e-143
Identity = 231/539 (42.86%), Postives = 345/539 (64.01%), Query Frame = 1 
Query:   46 SVSSNPSKMRIKAFPTSMSDQSVSKIWECLKRAIIEIQKKNNSGLSFEELYRNAYTMVLQKNGEQLYNGTKAVVTDHMIKIRDEVLERL-TNNFLAFLNRCWKDHITAMVMIRDILMYMDRVYVTTTDK--PNVYNTGMIIFRDTVLRHEAIRRHLRVTLLDMVKRERHGEVISRLQLRDACQMLAQLGVDKLNIYEEDFENYFLEQSRDFYRSESERLLT-ENASNLYITQVNKIIEDEAKRARDFLNSTTEAKIVQVLNEELIKNHIESVVNTENFGLTHMLSNKKYSEIALMFNLLKRVDN-------GLATMCSCISRFLREEGRKIVEDD---KTPQIYIQELIYXXXXXXXXXXXXXXXXQLFKNQINSDFEFFINQNSRSPEYLSLYIDDKLKRGTKGISDQDIDAIFDKCIILFRYLQDKDIFERYYKQHLAKRLLMSKSQSDDQEKSMISKLLIECGGVFTSKLEGMFKDMAISKTLMEEFHSQLQMYTTNTLGIDLFVRVLTTGLWPTQTATQTVCMPDEAQNAFSIYS 1620
            S +    KMRI+ F  ++ +Q V++ WE LKRAI EIQ+KNNSGLSFEELYRNAYTMVL K+GE+LYNG K V+ DHM  +R  ++E + + +FL  +   W DH  AMVMIRDILMYMDR+YV   +   P VYN G+  +R  +LR   I   +R  LL+++K +R    I+   +++AC ML  LG+D   +YE++FE   L+++ D+YR   +  L+ +N +  Y+ QV   + DEA RA  +L+  TEAKI+QV+++ ++  HI+++V  +N G+  ML +KK  ++  +F + KR+ +       GL  +   +S +L E G  IV+++   K P  ++ EL+ L+D  + LL  A  +++ FKN+   DFE F+N N +SPE+++LY+DD L+ G K +SD ++D   D  +ILFRYLQ+KD+FE+Y+KQ+LAKRLL+ KS SDD EK++++KL  ECG  FT KLE MF+D  +  TL   F    +   T  + ID+ +RVLT G+WPT      V +P E   A+ +++
Sbjct:    5 SGNGGQQKMRIRPFMATIDEQYVTQTWELLKRAIQEIQRKNNSGLSFEELYRNAYTMVLHKHGERLYNGLKDVIQDHMASVRIRIIESMNSGSFLETVAESWADHTVAMVMIRDILMYMDRIYVAQNNHVLP-VYNLGLDAYRTEILRQNGIGDRIRDALLELIKLDRKSNQINWHGIKNACDMLISLGIDSRTVYEDEFERPLLKETSDYYRDVCKNWLSGDNDACFYLAQVEIAMHDEASRASRYLDKMTEAKILQVMDDVMVAEHIQTIVYMQNGGVKFMLEHKKIEDLTRIFRIFKRIGDSVTVPGGGLKALLKAVSEYLNETGSNIVKNEDLLKNPVNFVNELLQLKDYFSSLLTTAFADDRDFKNRFQHDFETFLNSNRQSPEFVALYMDDMLRSGLKCVSDAEMDNKLDNVMILFRYLQEKDVFEKYFKQYLAKRLLLDKSCSDDVEKALLAKLKTECGCQFTQKLENMFRDKELWLTLATSFRDWREAQPTK-MSIDISLRVLTAGVWPT-VQCNPVVLPQELSVAYEMFT 540
[Close]
BLAST of Cullin 3 vs. Ensembl Celegans
Match: cul-3 (Cullin-3 [Source:UniProtKB/Swiss-Prot;Acc:Q17391])

HSP 1 Score: 431.409 bits (1108), Expect = 4.278e-143
Identity = 231/539 (42.86%), Postives = 345/539 (64.01%), Query Frame = 1 
Query:   46 SVSSNPSKMRIKAFPTSMSDQSVSKIWECLKRAIIEIQKKNNSGLSFEELYRNAYTMVLQKNGEQLYNGTKAVVTDHMIKIRDEVLERL-TNNFLAFLNRCWKDHITAMVMIRDILMYMDRVYVTTTDK--PNVYNTGMIIFRDTVLRHEAIRRHLRVTLLDMVKRERHGEVISRLQLRDACQMLAQLGVDKLNIYEEDFENYFLEQSRDFYRSESERLLT-ENASNLYITQVNKIIEDEAKRARDFLNSTTEAKIVQVLNEELIKNHIESVVNTENFGLTHMLSNKKYSEIALMFNLLKRVDN-------GLATMCSCISRFLREEGRKIVEDD---KTPQIYIQELIYXXXXXXXXXXXXXXXXQLFKNQINSDFEFFINQNSRSPEYLSLYIDDKLKRGTKGISDQDIDAIFDKCIILFRYLQDKDIFERYYKQHLAKRLLMSKSQSDDQEKSMISKLLIECGGVFTSKLEGMFKDMAISKTLMEEFHSQLQMYTTNTLGIDLFVRVLTTGLWPTQTATQTVCMPDEAQNAFSIYS 1620
            S +    KMRI+ F  ++ +Q V++ WE LKRAI EIQ+KNNSGLSFEELYRNAYTMVL K+GE+LYNG K V+ DHM  +R  ++E + + +FL  +   W DH  AMVMIRDILMYMDR+YV   +   P VYN G+  +R  +LR   I   +R  LL+++K +R    I+   +++AC ML  LG+D   +YE++FE   L+++ D+YR   +  L+ +N +  Y+ QV   + DEA RA  +L+  TEAKI+QV+++ ++  HI+++V  +N G+  ML +KK  ++  +F + KR+ +       GL  +   +S +L E G  IV+++   K P  ++ EL+ L+D  + LL  A  +++ FKN+   DFE F+N N +SPE+++LY+DD L+ G K +SD ++D   D  +ILFRYLQ+KD+FE+Y+KQ+LAKRLL+ KS SDD EK++++KL  ECG  FT KLE MF+D  +  TL   F    +   T  + ID+ +RVLT G+WPT      V +P E   A+ +++
Sbjct:    5 SGNGGQQKMRIRPFMATIDEQYVTQTWELLKRAIQEIQRKNNSGLSFEELYRNAYTMVLHKHGERLYNGLKDVIQDHMASVRIRIIESMNSGSFLETVAESWADHTVAMVMIRDILMYMDRIYVAQNNHVLP-VYNLGLDAYRTEILRQNGIGDRIRDALLELIKLDRKSNQINWHGIKNACDMLISLGIDSRTVYEDEFERPLLKETSDYYRDVCKNWLSGDNDACFYLAQVEIAMHDEASRASRYLDKMTEAKILQVMDDVMVAEHIQTIVYMQNGGVKFMLEHKKIEDLTRIFRIFKRIGDSVTVPGGGLKALLKAVSEYLNETGSNIVKNEDLLKNPVNFVNELLQLKDYFSSLLTTAFADDRDFKNRFQHDFETFLNSNRQSPEFVALYMDDMLRSGLKCVSDAEMDNKLDNVMILFRYLQEKDVFEKYFKQYLAKRLLLDKSCSDDVEKALLAKLKTECGCQFTQKLENMFRDKELWLTLATSFRDWREAQPTK-MSIDISLRVLTAGVWPT-VQCNPVVLPQELSVAYEMFT 540
[Close]
BLAST of Cullin 3 vs. Ensembl Celegans
Match: cul-3 (Cullin-3 [Source:UniProtKB/Swiss-Prot;Acc:Q17391])

HSP 1 Score: 431.409 bits (1108), Expect = 4.278e-143
Identity = 231/539 (42.86%), Postives = 345/539 (64.01%), Query Frame = 1 
Query:   46 SVSSNPSKMRIKAFPTSMSDQSVSKIWECLKRAIIEIQKKNNSGLSFEELYRNAYTMVLQKNGEQLYNGTKAVVTDHMIKIRDEVLERL-TNNFLAFLNRCWKDHITAMVMIRDILMYMDRVYVTTTDK--PNVYNTGMIIFRDTVLRHEAIRRHLRVTLLDMVKRERHGEVISRLQLRDACQMLAQLGVDKLNIYEEDFENYFLEQSRDFYRSESERLLT-ENASNLYITQVNKIIEDEAKRARDFLNSTTEAKIVQVLNEELIKNHIESVVNTENFGLTHMLSNKKYSEIALMFNLLKRVDN-------GLATMCSCISRFLREEGRKIVEDD---KTPQIYIQELIYXXXXXXXXXXXXXXXXQLFKNQINSDFEFFINQNSRSPEYLSLYIDDKLKRGTKGISDQDIDAIFDKCIILFRYLQDKDIFERYYKQHLAKRLLMSKSQSDDQEKSMISKLLIECGGVFTSKLEGMFKDMAISKTLMEEFHSQLQMYTTNTLGIDLFVRVLTTGLWPTQTATQTVCMPDEAQNAFSIYS 1620
            S +    KMRI+ F  ++ +Q V++ WE LKRAI EIQ+KNNSGLSFEELYRNAYTMVL K+GE+LYNG K V+ DHM  +R  ++E + + +FL  +   W DH  AMVMIRDILMYMDR+YV   +   P VYN G+  +R  +LR   I   +R  LL+++K +R    I+   +++AC ML  LG+D   +YE++FE   L+++ D+YR   +  L+ +N +  Y+ QV   + DEA RA  +L+  TEAKI+QV+++ ++  HI+++V  +N G+  ML +KK  ++  +F + KR+ +       GL  +   +S +L E G  IV+++   K P  ++ EL+ L+D  + LL  A  +++ FKN+   DFE F+N N +SPE+++LY+DD L+ G K +SD ++D   D  +ILFRYLQ+KD+FE+Y+KQ+LAKRLL+ KS SDD EK++++KL  ECG  FT KLE MF+D  +  TL   F    +   T  + ID+ +RVLT G+WPT      V +P E   A+ +++
Sbjct:    5 SGNGGQQKMRIRPFMATIDEQYVTQTWELLKRAIQEIQRKNNSGLSFEELYRNAYTMVLHKHGERLYNGLKDVIQDHMASVRIRIIESMNSGSFLETVAESWADHTVAMVMIRDILMYMDRIYVAQNNHVLP-VYNLGLDAYRTEILRQNGIGDRIRDALLELIKLDRKSNQINWHGIKNACDMLISLGIDSRTVYEDEFERPLLKETSDYYRDVCKNWLSGDNDACFYLAQVEIAMHDEASRASRYLDKMTEAKILQVMDDVMVAEHIQTIVYMQNGGVKFMLEHKKIEDLTRIFRIFKRIGDSVTVPGGGLKALLKAVSEYLNETGSNIVKNEDLLKNPVNFVNELLQLKDYFSSLLTTAFADDRDFKNRFQHDFETFLNSNRQSPEFVALYMDDMLRSGLKCVSDAEMDNKLDNVMILFRYLQEKDVFEKYFKQYLAKRLLLDKSCSDDVEKALLAKLKTECGCQFTQKLENMFRDKELWLTLATSFRDWREAQPTK-MSIDISLRVLTAGVWPT-VQCNPVVLPQELSVAYEMFT 540
[Close]
BLAST of Cullin 3 vs. Ensembl Celegans
Match: cul-3 (Cullin-3 [Source:UniProtKB/Swiss-Prot;Acc:Q17391])

HSP 1 Score: 360.533 bits (924), Expect = 2.088e-116
Identity = 195/482 (40.46%), Postives = 301/482 (62.45%), Query Frame = 1 
Query:  214 MVLQKNGEQLYNGTKAVVTDHMIKIRDEVLERL-TNNFLAFLNRCWKDHITAMVMIRDILMYMDRVYVTTTDKP-NVYNTGMIIFRDTVLRHEAIRRHLRVTLLDMVKRERHGEVISRLQLRDACQMLAQLGVDKLNIYEEDFENYFLEQSRDFYRSESERLLT-ENASNLYITQVNKIIEDEAKRARDFLNSTTEAKIVQVLNEELIKNHIESVVNTENFGLTHMLSNKKYSEIALMFNLLKRVDN-------GLATMCSCISRFLREEGRKIVEDD---KTPQIYIQELIYXXXXXXXXXXXXXXXXQLFKNQINSDFEFFINQNSRSPEYLSLYIDDKLKRGTKGISDQDIDAIFDKCIILFRYLQDKDIFERYYKQHLAKRLLMSKSQSDDQEKSMISKLLIECGGVFTSKLEGMFKDMAISKTLMEEFHSQLQMYTTNTLGIDLFVRVLTTGLWPTQTATQTVCMPDEAQNAFSIYS 1620
            MVL K+GE+LYNG K V+ DHM  +R  ++E + + +FL  +   W DH  AMVMIRDILMYMDR+YV   +    VYN G+  +R  +LR   I   +R  LL+++K +R    I+   +++AC ML  LG+D   +YE++FE   L+++ D+YR   +  L+ +N +  Y+ QV   + DEA RA  +L+  TEAKI+QV+++ ++  HI+++V  +N G+  ML +KK  ++  +F + KR+ +       GL  +   +S +L E G  IV+++   K P  ++ EL+ L+D  + LL  A  +++ FKN+   DFE F+N N +SPE+++LY+DD L+ G K +SD ++D   D  +ILFRYLQ+KD+FE+Y+KQ+LAKRLL+ KS SDD EK++++KL  ECG  FT KLE MF+D  +  TL   F    +   T  + ID+ +RVLT G+WPT      V +P E   A+ +++
Sbjct:    1 MVLHKHGERLYNGLKDVIQDHMASVRIRIIESMNSGSFLETVAESWADHTVAMVMIRDILMYMDRIYVAQNNHVLPVYNLGLDAYRTEILRQNGIGDRIRDALLELIKLDRKSNQINWHGIKNACDMLISLGIDSRTVYEDEFERPLLKETSDYYRDVCKNWLSGDNDACFYLAQVEIAMHDEASRASRYLDKMTEAKILQVMDDVMVAEHIQTIVYMQNGGVKFMLEHKKIEDLTRIFRIFKRIGDSVTVPGGGLKALLKAVSEYLNETGSNIVKNEDLLKNPVNFVNELLQLKDYFSSLLTTAFADDRDFKNRFQHDFETFLNSNRQSPEFVALYMDDMLRSGLKCVSDAEMDNKLDNVMILFRYLQEKDVFEKYFKQYLAKRLLLDKSCSDDVEKALLAKLKTECGCQFTQKLENMFRDKELWLTLATSFRDWREAQPTK-MSIDISLRVLTAGVWPT-VQCNPVVLPQELSVAYEMFT 480
[Close]
BLAST of Cullin 3 vs. Ensembl Celegans
Match: cul-1 (Cullin-1 [Source:UniProtKB/Swiss-Prot;Acc:Q17389])

HSP 1 Score: 152.91 bits (385), Expect = 3.348e-39
Identity = 123/504 (24.40%), Postives = 243/504 (48.21%), Query Frame = 1 
Query:  232 GEQLYNGTKAVVTDHMIKIRDEVLERLTNNFLAFLNRCWKDHITAMVMIRDILMYMDRVYVTTT-DKPN-----VYNTGMIIFRDTVLRHEAIRRHLRVTLLDMVKRERHGEVISRLQLRDACQMLAQLGVD-------------KLNIYEEDFENYFLEQSRDFYRSESERLLTENASNL--YITQVNKIIEDEAKRARDFLNSTTEAKIVQVLNEELIKNHIESVVNTENFGLTHMLSNKKYSEIALMFNLLKRVDNGLATMCSCISRFLREEG-----RKIVEDDKTPQIYIQELIYXXXXXXXXXXXXXXXXQLFKNQINSDFEFFINQNS------------RSPEYLSLYIDDKLKRGTKGISDQDIDAIFDKCIILFRYLQDKDIFERYYKQHLAKRLLMSKSQSDDQEKSMISKLLIECGGVFTSKLEGMFKDMAISKTLMEEFHSQLQMYTTNTLG---IDLFVRVLTTGLWPTQTATQTVCMPDEAQNAFSIYS 1620
            G ++Y   +  V  ++I + ++  E    + L +    W++   +  ++  I  Y++R ++    D+ +     VY   +++++  +     ++  +   +L++++ ER G +I+   +    + L +LGVD             KL +Y+E FE  FLE +R FY  E+   L+ N  N+  Y+ +V   +  E  R + +LNS+T+  +       LI N ++ +    +FG   +L +K+  +++ MF L  RV NGL  +   +   + +EG     R  +E     ++Y++ L+ + +R   L+  +  N   F   ++     FIN N+            +S E L+ Y D  L++ +K   + +++ +  K +++F+Y+ DKD+F ++Y +  +KRL+   S SD+ E + I+KL   CG  +T++L  M  D  +SK L  +F  +      + LG   ++  V VL++G WPT   T  + +P +      I+ 
Sbjct:   81 GHEMYQRVEEYVKAYVIAVCEKGAELSGEDLLKYYTTEWENFRISSKVMDGIFAYLNRHWIRRELDEGHENIYMVYTLALVVWKRNLFND--LKDKVIDAMLELIRSERTGSMINSRYISGVVECLVELGVDDSETDAKKDAETKKLAVYKEFFEVKFLEATRGFYTQEAANFLS-NGGNVTDYMIKVETRLNQEDDRCQLYLNSSTKTPLATCCESVLISNQLDFL--QRHFG--GLLVDKRDDDLSRMFKLCDRVPNGLDELRKSLENHIAKEGHQALERVAMEAATDAKLYVKTLLEVHERYQSLVNRSFKNEPGFMQSLDKAATSFINNNAVTKRAPPQAQLTKSAELLARYCDQLLRKSSKMPDEAELEELQTKIMVVFKYIDDKDVFSKFYTKMFSKRLISELSASDEAEANFITKLKSMCGYEYTARLSKMVNDTQVSKDLTADFKEK----KADMLGQKSVEFNVLVLSSGSWPT-FPTTPITLPQQLSKTIEIFG 572
[Close]
BLAST of Cullin 3 vs. Ensembl Fly
Match: Cul3 (gene:FBgn0261268 transcript:FBtr0302158)

HSP 1 Score: 540.421 bits (1391), Expect = 0.000e+0
Identity = 276/534 (51.69%), Postives = 381/534 (71.35%), Query Frame = 1 
Query:   46 SVSSNP----SKMRIKAFPTSMSDQSVSKIWECLKRAIIEIQKKNNSGLSFEELYRNAYTMVLQKNGEQLYNGTKAVVTDHM-IKIRDEVLERLTNNFLAFLNRCWKDHITAMVMIRDILMYMDRVYVTTTDKPNVYNTGMIIFRDTVLRHEAIRRHLRVTLLDMVKRERHGEVISRLQLRDACQMLAQLGVDKLNIYEEDFENYFLEQSRDFYRSESERLLTENASNLYITQVNKIIEDEAKRARDFLNSTTEAKIVQVLNEELIKNHIESVVNTENFGLTHMLSNKKYSEIALMFNLLKRV-DNGLATMCSCISRFLREEGRKIVEDDK----TPQIYIQELIYXXXXXXXXXXXXXXXXQLFKNQINSDFEFFINQNSRSPEYLSLYIDDKLKRGTKGISDQDIDAIFDKCIILFRYLQDKDIFERYYKQHLAKRLLMSKSQSDDQEKSMISKLLIECGGVFTSKLEGMFKDMAISKTLMEEFHSQLQMYTTNTLGIDLFVRVLTTGLWPTQTATQTVCMPDEAQNAFSIY 1617
            ++  NP     KMRI+AFP SM ++ V  IW  LK AI EIQKKNNSGLSFE+LYRNAY MVL K+G +LY G + VV++H+  K+R +VLE L +NFL  LN+ W DH T+MVMIRDILMYMDRVYV   +  NVYN G+I+FRD V+R+  I++ LR  LL MV  ERHGE I+ L +++AC ML  LG++   +YEEDFE  FL QS  FY+ ES+  L EN + +YI +V   I +E+ RA  +L+  TE +IV+V+ EELIK H+  +V  EN G+ +M+ N K  ++A  + L  R+ + GL  +   +S +LRE+GR +V++++     P  ++Q L+ L+DR +  L+++  N+++FKN I+SDFE F+N N++SPEYLSL+IDDKLK+G KG+S+Q+I++I DK ++LFR+L +KD+FERYYK HLAKRLL++KS SDD EK+MISKL  ECG  FTSKLEGMFKDM++S T+M+EF + +     +  G++L VR+LTTG WPTQTAT    +P   + AF I+
Sbjct:    2 NLRGNPPKKEGKMRIRAFPASMDEKYVETIWASLKNAIQEIQKKNNSGLSFEQLYRNAYNMVLHKHGNRLYYGLREVVSEHLEHKVRADVLEALHSNFLPKLNQAWTDHQTSMVMIRDILMYMDRVYVQQREVDNVYNLGLILFRDQVVRYSEIQKALREKLLGMVMEERHGEAINHLAIKNACSMLITLGINSRTVYEEDFEKPFLAQSAAFYKFESQNFLAENNAGVYIKKVEARITEESSRAALYLDKDTEPRIVRVVEEELIKKHMRPIVEMENSGVVYMIKNSKTEDLACTYKLFSRLKEEGLKVIADTMSAYLREQGRMLVKEEENGNTNPITFVQNLLDLKDRFDQFLVHSFANDRIFKNVISSDFEHFLNLNNKSPEYLSLFIDDKLKKGGKGMSEQEIESILDKTMVLFRFLLEKDVFERYYKTHLAKRLLLNKSVSDDFEKNMISKLKTECGCQFTSKLEGMFKDMSVSNTIMDEFKNFVNNNNLSLGGVELTVRILTTGFWPTQTATPNCNIPAAPREAFDIF 535
[Close]
BLAST of Cullin 3 vs. Ensembl Fly
Match: Cul3 (gene:FBgn0261268 transcript:FBtr0302157)

HSP 1 Score: 540.421 bits (1391), Expect = 0.000e+0
Identity = 276/534 (51.69%), Postives = 381/534 (71.35%), Query Frame = 1 
Query:   46 SVSSNP----SKMRIKAFPTSMSDQSVSKIWECLKRAIIEIQKKNNSGLSFEELYRNAYTMVLQKNGEQLYNGTKAVVTDHM-IKIRDEVLERLTNNFLAFLNRCWKDHITAMVMIRDILMYMDRVYVTTTDKPNVYNTGMIIFRDTVLRHEAIRRHLRVTLLDMVKRERHGEVISRLQLRDACQMLAQLGVDKLNIYEEDFENYFLEQSRDFYRSESERLLTENASNLYITQVNKIIEDEAKRARDFLNSTTEAKIVQVLNEELIKNHIESVVNTENFGLTHMLSNKKYSEIALMFNLLKRV-DNGLATMCSCISRFLREEGRKIVEDDK----TPQIYIQELIYXXXXXXXXXXXXXXXXQLFKNQINSDFEFFINQNSRSPEYLSLYIDDKLKRGTKGISDQDIDAIFDKCIILFRYLQDKDIFERYYKQHLAKRLLMSKSQSDDQEKSMISKLLIECGGVFTSKLEGMFKDMAISKTLMEEFHSQLQMYTTNTLGIDLFVRVLTTGLWPTQTATQTVCMPDEAQNAFSIY 1617
            ++  NP     KMRI+AFP SM ++ V  IW  LK AI EIQKKNNSGLSFE+LYRNAY MVL K+G +LY G + VV++H+  K+R +VLE L +NFL  LN+ W DH T+MVMIRDILMYMDRVYV   +  NVYN G+I+FRD V+R+  I++ LR  LL MV  ERHGE I+ L +++AC ML  LG++   +YEEDFE  FL QS  FY+ ES+  L EN + +YI +V   I +E+ RA  +L+  TE +IV+V+ EELIK H+  +V  EN G+ +M+ N K  ++A  + L  R+ + GL  +   +S +LRE+GR +V++++     P  ++Q L+ L+DR +  L+++  N+++FKN I+SDFE F+N N++SPEYLSL+IDDKLK+G KG+S+Q+I++I DK ++LFR+L +KD+FERYYK HLAKRLL++KS SDD EK+MISKL  ECG  FTSKLEGMFKDM++S T+M+EF + +     +  G++L VR+LTTG WPTQTAT    +P   + AF I+
Sbjct:    2 NLRGNPPKKEGKMRIRAFPASMDEKYVETIWASLKNAIQEIQKKNNSGLSFEQLYRNAYNMVLHKHGNRLYYGLREVVSEHLEHKVRADVLEALHSNFLPKLNQAWTDHQTSMVMIRDILMYMDRVYVQQREVDNVYNLGLILFRDQVVRYSEIQKALREKLLGMVMEERHGEAINHLAIKNACSMLITLGINSRTVYEEDFEKPFLAQSAAFYKFESQNFLAENNAGVYIKKVEARITEESSRAALYLDKDTEPRIVRVVEEELIKKHMRPIVEMENSGVVYMIKNSKTEDLACTYKLFSRLKEEGLKVIADTMSAYLREQGRMLVKEEENGNTNPITFVQNLLDLKDRFDQFLVHSFANDRIFKNVISSDFEHFLNLNNKSPEYLSLFIDDKLKKGGKGMSEQEIESILDKTMVLFRFLLEKDVFERYYKTHLAKRLLLNKSVSDDFEKNMISKLKTECGCQFTSKLEGMFKDMSVSNTIMDEFKNFVNNNNLSLGGVELTVRILTTGFWPTQTATPNCNIPAAPREAFDIF 535
[Close]
BLAST of Cullin 3 vs. Ensembl Fly
Match: Cul3 (gene:FBgn0261268 transcript:FBtr0302156)

HSP 1 Score: 540.421 bits (1391), Expect = 0.000e+0
Identity = 276/534 (51.69%), Postives = 381/534 (71.35%), Query Frame = 1 
Query:   46 SVSSNP----SKMRIKAFPTSMSDQSVSKIWECLKRAIIEIQKKNNSGLSFEELYRNAYTMVLQKNGEQLYNGTKAVVTDHM-IKIRDEVLERLTNNFLAFLNRCWKDHITAMVMIRDILMYMDRVYVTTTDKPNVYNTGMIIFRDTVLRHEAIRRHLRVTLLDMVKRERHGEVISRLQLRDACQMLAQLGVDKLNIYEEDFENYFLEQSRDFYRSESERLLTENASNLYITQVNKIIEDEAKRARDFLNSTTEAKIVQVLNEELIKNHIESVVNTENFGLTHMLSNKKYSEIALMFNLLKRV-DNGLATMCSCISRFLREEGRKIVEDDK----TPQIYIQELIYXXXXXXXXXXXXXXXXQLFKNQINSDFEFFINQNSRSPEYLSLYIDDKLKRGTKGISDQDIDAIFDKCIILFRYLQDKDIFERYYKQHLAKRLLMSKSQSDDQEKSMISKLLIECGGVFTSKLEGMFKDMAISKTLMEEFHSQLQMYTTNTLGIDLFVRVLTTGLWPTQTATQTVCMPDEAQNAFSIY 1617
            ++  NP     KMRI+AFP SM ++ V  IW  LK AI EIQKKNNSGLSFE+LYRNAY MVL K+G +LY G + VV++H+  K+R +VLE L +NFL  LN+ W DH T+MVMIRDILMYMDRVYV   +  NVYN G+I+FRD V+R+  I++ LR  LL MV  ERHGE I+ L +++AC ML  LG++   +YEEDFE  FL QS  FY+ ES+  L EN + +YI +V   I +E+ RA  +L+  TE +IV+V+ EELIK H+  +V  EN G+ +M+ N K  ++A  + L  R+ + GL  +   +S +LRE+GR +V++++     P  ++Q L+ L+DR +  L+++  N+++FKN I+SDFE F+N N++SPEYLSL+IDDKLK+G KG+S+Q+I++I DK ++LFR+L +KD+FERYYK HLAKRLL++KS SDD EK+MISKL  ECG  FTSKLEGMFKDM++S T+M+EF + +     +  G++L VR+LTTG WPTQTAT    +P   + AF I+
Sbjct:    2 NLRGNPPKKEGKMRIRAFPASMDEKYVETIWASLKNAIQEIQKKNNSGLSFEQLYRNAYNMVLHKHGNRLYYGLREVVSEHLEHKVRADVLEALHSNFLPKLNQAWTDHQTSMVMIRDILMYMDRVYVQQREVDNVYNLGLILFRDQVVRYSEIQKALREKLLGMVMEERHGEAINHLAIKNACSMLITLGINSRTVYEEDFEKPFLAQSAAFYKFESQNFLAENNAGVYIKKVEARITEESSRAALYLDKDTEPRIVRVVEEELIKKHMRPIVEMENSGVVYMIKNSKTEDLACTYKLFSRLKEEGLKVIADTMSAYLREQGRMLVKEEENGNTNPITFVQNLLDLKDRFDQFLVHSFANDRIFKNVISSDFEHFLNLNNKSPEYLSLFIDDKLKKGGKGMSEQEIESILDKTMVLFRFLLEKDVFERYYKTHLAKRLLLNKSVSDDFEKNMISKLKTECGCQFTSKLEGMFKDMSVSNTIMDEFKNFVNNNNLSLGGVELTVRILTTGFWPTQTATPNCNIPAAPREAFDIF 535
[Close]
BLAST of Cullin 3 vs. Ensembl Fly
Match: Cul3 (gene:FBgn0261268 transcript:FBtr0302159)

HSP 1 Score: 528.094 bits (1359), Expect = 1.209e-178
Identity = 269/519 (51.83%), Postives = 372/519 (71.68%), Query Frame = 1 
Query:   79 KAFPTSMSDQSVSKIWECLKRAIIEIQKKNNSGLSFEELYRNAYTMVLQKNGEQLYNGTKAVVTDHM-IKIRDEVLERLTNNFLAFLNRCWKDHITAMVMIRDILMYMDRVYVTTTDKPNVYNTGMIIFRDTVLRHEAIRRHLRVTLLDMVKRERHGEVISRLQLRDACQMLAQLGVDKLNIYEEDFENYFLEQSRDFYRSESERLLTENASNLYITQVNKIIEDEAKRARDFLNSTTEAKIVQVLNEELIKNHIESVVNTENFGLTHMLSNKKYSEIALMFNLLKRV-DNGLATMCSCISRFLREEGRKIVEDDK----TPQIYIQELIYXXXXXXXXXXXXXXXXQLFKNQINSDFEFFINQNSRSPEYLSLYIDDKLKRGTKGISDQDIDAIFDKCIILFRYLQDKDIFERYYKQHLAKRLLMSKSQSDDQEKSMISKLLIECGGVFTSKLEGMFKDMAISKTLMEEFHSQLQMYTTNTLGIDLFVRVLTTGLWPTQTATQTVCMPDEAQNAFSIY 1617
            +AF  SM ++ V  IW  LK AI EIQKKNNSGLSFE+LYRNAY MVL K+G +LY G + VV++H+  K+R +VLE L +NFL  LN+ W DH T+MVMIRDILMYMDRVYV   +  NVYN G+I+FRD V+R+  I++ LR  LL MV  ERHGE I+ L +++AC ML  LG++   +YEEDFE  FL QS  FY+ ES+  L EN + +YI +V   I +E+ RA  +L+  TE +IV+V+ EELIK H+  +V  EN G+ +M+ N K  ++A  + L  R+ + GL  +   +S +LRE+GR +V++++     P  ++Q L+ L+DR +  L+++  N+++FKN I+SDFE F+N N++SPEYLSL+IDDKLK+G KG+S+Q+I++I DK ++LFR+L +KD+FERYYK HLAKRLL++KS SDD EK+MISKL  ECG  FTSKLEGMFKDM++S T+M+EF + +     +  G++L VR+LTTG WPTQTAT    +P   + AF I+
Sbjct:  178 RAFNASMDEKYVETIWASLKNAIQEIQKKNNSGLSFEQLYRNAYNMVLHKHGNRLYYGLREVVSEHLEHKVRADVLEALHSNFLPKLNQAWTDHQTSMVMIRDILMYMDRVYVQQREVDNVYNLGLILFRDQVVRYSEIQKALREKLLGMVMEERHGEAINHLAIKNACSMLITLGINSRTVYEEDFEKPFLAQSAAFYKFESQNFLAENNAGVYIKKVEARITEESSRAALYLDKDTEPRIVRVVEEELIKKHMRPIVEMENSGVVYMIKNSKTEDLACTYKLFSRLKEEGLKVIADTMSAYLREQGRMLVKEEENGNTNPITFVQNLLDLKDRFDQFLVHSFANDRIFKNVISSDFEHFLNLNNKSPEYLSLFIDDKLKKGGKGMSEQEIESILDKTMVLFRFLLEKDVFERYYKTHLAKRLLLNKSVSDDFEKNMISKLKTECGCQFTSKLEGMFKDMSVSNTIMDEFKNFVNNNNLSLGGVELTVRILTTGFWPTQTATPNCNIPAAPREAFDIF 696
[Close]
BLAST of Cullin 3 vs. Ensembl Fly
Match: Cul4 (gene:FBgn0033260 transcript:FBtr0301355)

HSP 1 Score: 295.049 bits (754), Expect = 3.640e-90
Identity = 183/539 (33.95%), Postives = 296/539 (54.92%), Query Frame = 1 
Query:   37 LDSSVSSNPSKMRIKAF---PTSMSDQSVSKIWECLKRAIIEIQKKNNSGLSFEELYRNAYTMVLQKNGEQLYNGTKAVVTDHMIKIRDEVLERLTNN------FLAFLNRCWKDHITAMVMIRDILMYMDRVYV-TTTDKPNVYNTGMIIFRDTVLRHEAIRRHLRVTLLDMVKRERHGEVISRLQLRDACQMLAQLGVDKLNIYEEDFENYFLEQSRDFYRSESERLLTENASNLYITQVNKIIEDEAKRARDFLNSTTEAKIVQVLNEELIKNHIESVVNTENFGLTHMLSNKKYSEIALMFNLLKRVDNGLATMCSCISRFLREEGRKIVEDDKTPQIYIQELIYXXXXXXXXXXXXXXXXQLFKNQINSDFEFFINQNSRSP-EYLSLYIDDKLKRGTKGISDQDIDAIFDKCIILFRYLQDKDIFERYYKQHLAKRLLMSKSQSDDQEKSMISKLLIECGGVFTSKLEGMFKDMAISKTLMEEFHSQLQMYTTNTLGIDLFVRVLTTGLWPTQTATQTVCMPDEAQNAFSIYS 1620
            + +S   +  K+ IK F   PT + D      +  L+ A+I IQ       S EELY+    M   K   QLY   K +   H+   R+  L+ LT         L  +N  W      M+MIR I +YMDR YV   +   ++++ G+ +FR    ++  +++     LL ++++ER G  + R  L+   +ML  L      IY   FE  FL+ +   Y++ES+R + E     Y+  VNK + +E +R R +L+S+T+  ++  + +EL+  H+ S++     GL  +L + + S++ L++ LL RV NG + +C   + F++++GR IV D +  +  +Q+L+  +D+ + ++     +N+ F N +   FEFFINQ +  P E ++ Y+D KL+ G KG +D++++   DK ++LFR++  KD+FE +YK+ LAKRLL+ KS S D EKSM+SKL  ECGG FTSKLEGMFKDM +S+ +   F         +   +DL V +LT G WPT   T+ V MP +  N   I++
Sbjct:   91 IHNSKPGDVKKIVIKNFKDKPT-LPDNYSKDTYVKLEEAVIAIQLSKPIKYSLEELYQAVVNMCSHKMDAQLYAKLKELTEQHVK--RNIKLKELTGGSMDKLILLEKINHWWLSFCQQMIMIRSIFLYMDRTYVLQNSTVHSIWDMGLDLFRIHFAQNSVVQKRTVDGLLTLIEKERQGSTVDRGLLKSLVRMLCDL-----QIYTSSFEEKFLDATNQLYKAESQRKMQELEVPEYLQHVNKRLAEENERLRHYLDSSTKHPLIYNVEKELLAEHLTSILQK---GLDSLLEDNRLSDLTLLYGLLSRVKNGTSELCGNFNGFIKKKGRTIVIDPEKDKSMVQDLLDFKDKMDVIVRTCFEHNEKFTNSLREAFEFFINQRANKPAELIAKYVDMKLRSGNKGTTDEELEKTLDKIMVLFRFIHGKDVFEAFYKKDLAKRLLVGKSASVDSEKSMLSKLKQECGGGFTSKLEGMFKDMELSRDINIAFRGHALSNNRDVHNLDLCVSILTMGYWPTYAPTE-VTMPPQFINPQQIFN 617
[Close]
BLAST of Cullin 3 vs. Ensembl Zebrafish
Match: cul3b (cullin 3b [Source:ZFIN;Acc:ZDB-GENE-081007-1])

HSP 1 Score: 594.349 bits (1531), Expect = 0.000e+0
Identity = 292/531 (54.99%), Postives = 389/531 (73.26%), Query Frame = 1 
Query:   37 LDSSVSSNPSKMRIKAFPTSMSDQSVSKIWECLKRAIIEIQKKNNSGLSFEELYRNAYTMVLQKNGEQLYNGTKAVVTDHMI-KIRDEVLERLTNNFLAFLNRCWKDHITAMVMIRDILMYMDRVYVTTTDKPNVYNTGMIIFRDTVLRHEAIRRHLRVTLLDMVKRERHGEVISRLQLRDACQMLAQLGVDKLNIYEEDFENYFLEQSRDFYRSESERLLTENASNLYITQVNKIIEDEAKRARDFLNSTTEAKIVQVLNEELIKNHIESVVNTENFGLTHMLSNKKYSEIALMFNLLKRVDNGLATMCSCISRFLREEGRKIVEDD---KTPQIYIQELIYXXXXXXXXXXXXXXXXQLFKNQINSDFEFFINQNSRSPEYLSLYIDDKLKRGTKGISDQDIDAIFDKCIILFRYLQDKDIFERYYKQHLAKRLLMSKSQSDDQEKSMISKLLIECGGVFTSKLEGMFKDMAISKTLMEEFHSQLQMYTTNTLGIDLFVRVLTTGLWPTQTATQTVCMPDEAQNAFSIY 1617
            L    +   +KMRI+AFP +M ++ V+ IW+ LK AI EIQ+KNNSGLSFEELYRNAYTMVL K+GE+LY G + VVT+H+I K+R++VL  L NNFL  LN+ W DH TAMVMIRDILMYMDRVYV   +  NVYN G+IIFRD V+R+  IR HLR TLLDM+ RER GEV+ R  +R+ACQML  LG++  ++YEEDFE  FLE S +F++ ES++ L EN++++YI +V   I +E +R    L+ +TE  IV+V+  ELI  H++++V  EN GL HML N K  ++A M+ L  RV NGL TMC C+S +LRE+G+ +V ++   K P  YIQ L+ L+ R +  L  +  N++LFK  I  DFE+F+N NSRSPEYLSL+IDDKLK+G KG+++Q++++I DK ++LFR++Q+KD+FERYYKQHLA+RLL +KS SDD EK+MISKL  ECG  FTSKLEGMF+DM+IS T M+EF   L     +  G+DL VRVLTTG WPTQ+AT    +P   ++AF ++
Sbjct:    4 LSKGGTKKDTKMRIRAFPMTMDEKYVNNIWDLLKNAIQEIQRKNNSGLSFEELYRNAYTMVLHKHGEKLYTGLREVVTEHLINKVREDVLNSLNNNFLQTLNQAWNDHQTAMVMIRDILMYMDRVYVQQNNVENVYNLGLIIFRDQVVRYGCIRDHLRQTLLDMIARERKGEVVDRGAIRNACQMLMILGLEGRSVYEEDFEAPFLEMSAEFFQMESQKFLAENSASVYIKKVEARINEEIERVIHCLDKSTEEPIVKVVERELISKHMKTIVEMENSGLVHMLKNGKTEDLACMYKLFSRVPNGLKTMCECMSSYLREQGKALVSEEGEGKNPVDYIQGLLDLKSRFDRFLQESFNNDRLFKQTIAGDFEYFLNLNSRSPEYLSLFIDDKLKKGVKGLTEQEVESILDKAMVLFRFMQEKDVFERYYKQHLARRLLTNKSVSDDSEKNMISKLKTECGCQFTSKLEGMFRDMSISNTTMDEFRQHLTSTGVSLGGVDLIVRVLTTGYWPTQSATPKCNIPPSPRHAFEVF 534
[Close]
BLAST of Cullin 3 vs. Ensembl Zebrafish
Match: cul3a (cullin 3a [Source:ZFIN;Acc:ZDB-GENE-030131-3376])

HSP 1 Score: 593.964 bits (1530), Expect = 0.000e+0
Identity = 291/522 (55.75%), Postives = 388/522 (74.33%), Query Frame = 1 
Query:   64 SKMRIKAFPTSMSDQSVSKIWECLKRAIIEIQKKNNSGLSFEELYRNAYTMVLQKNGEQLYNGTKAVVTDHMI-KIRDEVLERLTNNFLAFLNRCWKDHITAMVMIRDILMYMDRVYVTTTDKPNVYNTGMIIFRDTVLRHEAIRRHLRVTLLDMVKRERHGEVISRLQLRDACQMLAQLGVDKLNIYEEDFENYFLEQSRDFYRSESERLLTENASNLYITQVNKIIEDEAKRARDFLNSTTEAKIVQVLNEELIKNHIESVVNTENFGLTHMLSNKKYSEIALMFNLLKRVDNGLATMCSCISRFLREEGRKIVEDD---KTPQIYIQELIYXXXXXXXXXXXXXXXXQLFKNQINSDFEFFINQNSRSPEYLSLYIDDKLKRGTKGISDQDIDAIFDKCIILFRYLQDKDIFERYYKQHLAKRLLMSKSQSDDQEKSMISKLLIECGGVFTSKLEGMFKDMAISKTLMEEFHSQLQMYTTNTLGIDLFVRVLTTGLWPTQTATQTVCMPDEAQNAFSIY 1617
            +KMRI+AFP +M ++ V+ IW+ LK AI EIQ+KNNSGLSFEELYRNAYTMVL K+GE+LY G + VVT+H+I K+R++VL  L NNFL  LN+ W DH TAMVMIRDILMYMDRVYV   +  NVYN G+IIFRD V+R+  IR HLR TLLDM+ RER GEV+ R  +R+ACQML  LG++  ++YEEDFE  FL+ S +F++ ES++ L EN++++YI +V   I +E +R    L+ +TE  IV+V+  ELI  H++++V  EN GL HML N K  ++A M+ L  RV NGL TMC C+S +LRE+G+ +V ++   K P  YIQ L+ L+ R +  L  +  N++LFK  I  DFE+F+N NSRSPEYLSL+IDDKLK+G KG+++Q++++I DK ++LFR++Q+KD+FERYYKQHLA+RLL +KS SDD EK+MISKL  ECG  FTSKLEGMF+DM+IS T M+EF   LQ    +  G+DL VRVLTTG WPTQ+AT    +P   ++AF ++
Sbjct:   20 TKMRIRAFPMTMDEKYVNNIWDLLKNAIQEIQRKNNSGLSFEELYRNAYTMVLHKHGEKLYTGLREVVTEHLINKVREDVLHSLNNNFLQTLNQAWNDHQTAMVMIRDILMYMDRVYVQQNNVENVYNLGLIIFRDQVVRYGCIRDHLRQTLLDMIARERRGEVVDRGAIRNACQMLMVLGLEGRSVYEEDFEIPFLDMSAEFFQMESQKFLAENSASVYIKKVEARINEEIERVMHCLDKSTEEPIVKVVERELISKHMKTIVEMENSGLVHMLKNGKTEDLACMYKLFGRVPNGLKTMCECMSWYLREQGKALVSEEGEGKNPVDYIQGLLDLKSRFDRFLQESFNNDRLFKQTIAGDFEYFLNLNSRSPEYLSLFIDDKLKKGVKGLTEQEVESILDKAMVLFRFMQEKDVFERYYKQHLARRLLTNKSVSDDSEKNMISKLKTECGCQFTSKLEGMFRDMSISNTTMDEFRHHLQTSQVSLCGVDLTVRVLTTGYWPTQSATPKCNIPPSPRHAFEVF 541
[Close]
BLAST of Cullin 3 vs. Ensembl Zebrafish
Match: cul3b (cullin 3b [Source:ZFIN;Acc:ZDB-GENE-081007-1])

HSP 1 Score: 592.038 bits (1525), Expect = 0.000e+0
Identity = 292/531 (54.99%), Postives = 389/531 (73.26%), Query Frame = 1 
Query:   37 LDSSVSSNPSKMRIKAFPTSMSDQSVSKIWECLKRAIIEIQKKNNSGLSFEELYRNAYTMVLQKNGEQLYNGTKAVVTDHMI-KIRDEVLERLTNNFLAFLNRCWKDHITAMVMIRDILMYMDRVYVTTTDKPNVYNTGMIIFRDTVLRHEAIRRHLRVTLLDMVKRERHGEVISRLQLRDACQMLAQLGVDKLNIYEEDFENYFLEQSRDFYRSESERLLTENASNLYITQVNKIIEDEAKRARDFLNSTTEAKIVQVLNEELIKNHIESVVNTENFGLTHMLSNKKYSEIALMFNLLKRVDNGLATMCSCISRFLREEGRKIVEDD---KTPQIYIQELIYXXXXXXXXXXXXXXXXQLFKNQINSDFEFFINQNSRSPEYLSLYIDDKLKRGTKGISDQDIDAIFDKCIILFRYLQDKDIFERYYKQHLAKRLLMSKSQSDDQEKSMISKLLIECGGVFTSKLEGMFKDMAISKTLMEEFHSQLQMYTTNTLGIDLFVRVLTTGLWPTQTATQTVCMPDEAQNAFSIY 1617
            L    +   +KMRI+AFP +M ++ V+ IW+ LK AI EIQ+KNNSGLSFEELYRNAYTMVL K+GE+LY G + VVT+H+I K+R++VL  L NNFL  LN+ W DH TAMVMIRDILMYMDRVYV   +  NVYN G+IIFRD V+R+  IR HLR TLLDM+ RER GEV+ R  +R+ACQML  LG++  ++YEEDFE  FLE S +F++ ES++ L EN++++YI +V   I +E +R    L+ +TE  IV+V+  ELI  H++++V  EN GL HML N K  ++A M+ L  RV NGL TMC C+S +LRE+G+ +V ++   K P  YIQ L+ L+ R +  L  +  N++LFK  I  DFE+F+N NSRSPEYLSL+IDDKLK+G KG+++Q++++I DK ++LFR++Q+KD+FERYYKQHLA+RLL +KS SDD EK+MISKL  ECG  FTSKLEGMF+DM+IS T M+EF   L     +  G+DL VRVLTTG WPTQ+AT    +P   ++AF ++
Sbjct:    4 LSKGGTKKDTKMRIRAFPMTMDEKYVNNIWDLLKNAIQEIQRKNNSGLSFEELYRNAYTMVLHKHGEKLYTGLREVVTEHLINKVREDVLNSLNNNFLQTLNQAWNDHQTAMVMIRDILMYMDRVYVQQNNVENVYNLGLIIFRDQVVRYGCIRDHLRQTLLDMIARERKGEVVDRGAIRNACQMLMILGLEGRSVYEEDFEAPFLEMSAEFFQMESQKFLAENSASVYIKKVEARINEEIERVIHCLDKSTEEPIVKVVERELISKHMKTIVEMENSGLVHMLKNGKTEDLACMYKLFSRVPNGLKTMCECMSSYLREQGKALVSEEGEGKNPVDYIQGLLDLKSRFDRFLQESFNNDRLFKQTIAGDFEYFLNLNSRSPEYLSLFIDDKLKKGVKGLTEQEVESILDKAMVLFRFMQEKDVFERYYKQHLARRLLTNKSVSDDSEKNMISKLKTECGCQFTSKLEGMFRDMSISNTTMDEFRQHLTSTGVSLGGVDLIVRVLTTGYWPTQSATPKCNIPPSPRHAFEVF 534
[Close]
BLAST of Cullin 3 vs. Ensembl Zebrafish
Match: cul4a (cullin 4A [Source:ZFIN;Acc:ZDB-GENE-040426-1357])

HSP 1 Score: 286.574 bits (732), Expect = 1.152e-88
Identity = 174/536 (32.46%), Postives = 291/536 (54.29%), Query Frame = 1 
Query:   43 SSVSSNPSKMRIKAFP--TSMSDQSVSKIWECLKRAIIEIQKKNNSGLSFEELYRNAYTMVLQKNGEQLYNGTKAVVTDH----MIKIRDEVLERLTNNFLAFLNRCWKDHITAMVMIRDILMYMDRVYVTTTDK-PNVYNTGMIIFRDTVLRHEAIRRHLRVTLLDMVKRERHGEVISRLQLRDACQMLAQLGVDKLNIYEEDFENYFLEQSRDFYRSESERLLTENASNLYITQVNKIIEDEAKRARDFLNSTTEAKIVQVLNEELIKNHIESVVNTENFGLTHMLSNKKYSEIALMFNLLKRVDNGLATMCSCISRFLREEGRKIVEDDKTPQIYIQELIYXXXXXXXXXXXXXXXXQLFKNQINSDFEFFINQNSRSP-EYLSLYIDDKLKRGTKGISDQDIDAIFDKCIILFRYLQDKDIFERYYKQHLAKRLLMSKSQSDDQEKSMISKLLIECGGVFTSKLEGMFKDMAISKTLMEEFHSQLQMYTTNTLGIDLFVRVLTTGLWPTQTATQTVCMPDEA---QNAFSIY 1617
            S+ +    K+ IK F     ++D      W  L+ A+  IQ   +   + EELY+    +   K    LY   + V  +H    + + R+E L+ L+  FL  +NRCW+DH    +MIR I +++DR YV      P++++TG+ +FR  ++   A++      +L+ V+RER GE + R  LR    ML+ L      +Y++ FE  FL ++   Y +E +RL+ E     Y+  V + +E+E  R   +L+ +T+  ++  + ++L+  H+ +++     GL  +L   +  E+ L++ L  +V  GL  +      +++  G + V   +  +  +QEL+  +D+ + +  +    N+ F N +   FE FINQ    P E ++ Y+D KL+ G K  ++++++ I DK +I+FR++  KD+FE +YK+ LAKRLL+ KS S D EKSM+SKL  ECG  FTSKLEGMFKDM +SK +M +F   +Q  T  +  I+L V +LT G WP+ T    V +P E    Q  F ++
Sbjct:   19 SAKAGASKKLVIKNFKDRPKLTDSYTEDTWLKLRDAVSAIQNSTSIQYNLEELYQAVENLCSYKVSPMLYKQLRQVCEEHVQAQIHQFREESLDSLS--FLKRMNRCWQDHCRQTIMIRSIFLFLDRTYVLQNSLLPSIWDTGLELFRTHIVSDAAVQSRTVQGILEQVERERSGETVDRSLLRSLLGMLSDL-----QVYKDSFEQRFLSETTRLYAAEGQRLMQERDVPEYLHHVARRLEEENDRVISYLDQSTQKPLIATVEKQLLGEHMTTILQK---GLRTLLDENRVCELTLLYELFSKVKGGLTALLQSWREYIKSVGAETVCSPERDREMVQELLDFKDQMDSVTQSCFQRNESFINAMKEAFENFINQRPNKPAELIAKYVDSKLRAGNKEATEEELERILDKIMIIFRFIHGKDVFEAFYKKDLAKRLLVGKSASVDAEKSMLSKLKHECGAAFTSKLEGMFKDMELSKDIMIQFKQYMQNQTEPS-NIELTVNILTMGYWPSYTPMD-VHLPAEMVKLQEVFKLF 542
[Close]
BLAST of Cullin 3 vs. Ensembl Zebrafish
Match: cul4b (cullin 4B [Source:ZFIN;Acc:ZDB-GENE-041008-208])

HSP 1 Score: 275.018 bits (702), Expect = 2.003e-82
Identity = 173/532 (32.52%), Postives = 293/532 (55.08%), Query Frame = 1 
Query:   19 SGNIRKLDSSVSSNPSKMRIKAFP--TSMSDQSVSKIWECLKRAIIEIQKKNNSGLSFEELYRNAYTMVLQKNGEQLYNGTKAVVTDHMIKIRDEVLERLTNN--FLAFLNRCWKDHITAMVMIRDILMYMDRVYVTTTDK-PNVYNTGMIIFRDTVLRHEAIRRHLRVTLLDMVKRERHGEVISRLQLRDACQMLAQLGVDKLNIYEEDFENYFLEQSRDFYRSESERLLTENASNLYITQVNKIIEDEAKRARDFLNSTTEAKIVQVLNEELIKNHIESVVNTENFGLTHMLSNKKYSEIALMFNLLKRVDNGLATMCSCISRFLREEGRKIVEDDKTPQIYIQELIYXXXXXXXXXXXXXXXXQLFKNQINSDFEFFINQNSRSP-EYLSLYIDDKLKRGTKGISDQDIDAIFDKCIILFRYLQDKDIFERYYKQHLAKRLLMSKSQSDDQEKSMISKLLIECGGVFTSKLEGMFKDMAISKTLMEEFHSQLQMYTTNTLG-IDLFVRVLTTGLWPTQTATQTVCMPDE 1593
            S       +S      K+ IK F     + +   ++ W+ LK A+  IQ   +   + EELY+    +   K   +LY   + V  DH+    D+  E   ++  FL  +++CW+DH   M+MIR I +++DR YV      P++++ G+ +FR  ++    ++      +L +++RER GE + R  LR    ML+ L      IY++ FE  FLE++   Y +E +RL+ E     Y+  VNK +E+EA R   +L+ +T+  ++  + ++L+  H+ +++     GL ++L   +  +++L++ L  RV  G+  +      +++  G  IV + +  +  +QEL+  +D+ + ++    + N+ F N +   FE FIN+    P E ++ Y+D KL+ G K  +D++++ + DK +I+FR++  KD+FE +YK+ LAKRLL+ KS S D EKSM+SKL  ECG  FTSKLEGMFKDM +SK +M +F   +Q    N  G I+L V +LT G WPT    + V +P E
Sbjct:  131 SAGSATFSNSKPGAAKKLVIKNFKEKPKLPENYTNETWQKLKEAVEAIQNSTSIKYNLEELYQAVENLCSHKISAKLYKQLRVVCEDHIKAQIDQFREDALDSVLFLKKIDKCWQDHCRQMIMIRSIFLFLDRTYVLQNSMLPSIWDMGLELFRFYIISDLKVQSKTIDGILLLIERERSGEAVDRSLLRSLLSMLSDL-----QIYQDSFEQRFLEETNRLYAAEGQRLMQEREVPEYLHHVNKRLEEEADRVITYLDQSTQKSLIATVEKQLLGEHLTAILQK---GLNNLLDENRIQDLSLLYQLFSRVRGGVQVLLQHWIEYIKAFGSTIVINPEKDKTMVQELLDFKDKVDHIIDVCFMKNEKFVNGMKEAFETFINKRPNKPAELIAKYVDSKLRAGNKEATDEELEKMLDKIMIIFRFIYGKDVFEAFYKKDLAKRLLVGKSASVDAEKSMLSKLKHECGAAFTSKLEGMFKDMELSKDIMVQFKQHMQ--CQNIPGNIELTVNILTMGYWPTYVPME-VHLPAE 651
[Close]
BLAST of Cullin 3 vs. Ensembl Xenopus
Match: cul3 (cullin 3 [Source:NCBI gene;Acc:548729])

HSP 1 Score: 598.586 bits (1542), Expect = 0.000e+0
Identity = 295/529 (55.77%), Postives = 391/529 (73.91%), Query Frame = 1 
Query:   43 SSVSSNPSKMRIKAFPTSMSDQSVSKIWECLKRAIIEIQKKNNSGLSFEELYRNAYTMVLQKNGEQLYNGTKAVVTDHMI-KIRDEVLERLTNNFLAFLNRCWKDHITAMVMIRDILMYMDRVYVTTTDKPNVYNTGMIIFRDTVLRHEAIRRHLRVTLLDMVKRERHGEVISRLQLRDACQMLAQLGVDKLNIYEEDFENYFLEQSRDFYRSESERLLTENASNLYITQVNKIIEDEAKRARDFLNSTTEAKIVQVLNEELIKNHIESVVNTENFGLTHMLSNKKYSEIALMFNLLKRVDNGLATMCSCISRFLREEGRKIVEDD---KTPQIYIQELIYXXXXXXXXXXXXXXXXQLFKNQINSDFEFFINQNSRSPEYLSLYIDDKLKRGTKGISDQDIDAIFDKCIILFRYLQDKDIFERYYKQHLAKRLLMSKSQSDDQEKSMISKLLIECGGVFTSKLEGMFKDMAISKTLMEEFHSQLQMYTTNTLGIDLFVRVLTTGLWPTQTATQTVCMPDEAQNAFSIY 1617
            S+ S   +KMRI+AFP +M ++ V+ IW+ LK AI EIQ+KNNSGLSFEELYRNAYTMVL K+GE+LY G + VVT+H+I K+R++VL  L NNFL  LN+ W DH TAMVMIRDILMYMDRVYV   +  NVYN G+IIFRD V+R+  IR HLR TLLDM+ RER GEV+ R  +R+ACQML  LG++  ++YEEDFE  FLE S +F++ ES++ L EN++++YI +V   I +E +R    L+ +TE  IV+V+  ELI  H++++V  EN GL HML N K  ++A M+ L  RV NGL TMC C+S +LRE+G+ +V ++   K P  YIQ L+ L+ R +  L  +  N++LFK  I  DFE+F+N NSRSPEYLSL+IDDKLK+G KG+++Q++++I DK ++LFR++Q+KD+FERYYKQHLA+RLL +KS SDD EK+MISKL  ECG  FTSKLEGMF+DM+IS T M+EF   LQ    +  G+DL VRVLTTG WPTQ+AT    +P   ++AF I+
Sbjct:    7 STGSRKDTKMRIRAFPMTMDEKYVNSIWDLLKNAIQEIQRKNNSGLSFEELYRNAYTMVLHKHGEKLYTGLREVVTEHLINKVREDVLNSLNNNFLQTLNQAWNDHQTAMVMIRDILMYMDRVYVQQNNVENVYNLGLIIFRDQVVRYGCIRDHLRQTLLDMIARERKGEVVDRGAIRNACQMLMILGLEGRSVYEEDFEAPFLEMSAEFFQMESQKFLAENSASVYIKKVEARINEEIERVMHCLDKSTEEPIVKVVERELISKHMKTIVEMENSGLVHMLKNGKTEDLACMYKLFSRVPNGLKTMCECMSLYLREQGKALVSEEGEGKNPVDYIQGLLDLKSRFDRFLQESFSNDRLFKQTIAGDFEYFLNLNSRSPEYLSLFIDDKLKKGVKGLTEQEVESILDKAMVLFRFMQEKDVFERYYKQHLARRLLTNKSVSDDSEKNMISKLKTECGCQFTSKLEGMFRDMSISNTTMDEFRQHLQTTGVSLGGVDLTVRVLTTGYWPTQSATPKCNIPPAPRHAFEIF 535
[Close]
BLAST of Cullin 3 vs. Ensembl Xenopus
Match: cul3 (cullin 3 [Source:NCBI gene;Acc:548729])

HSP 1 Score: 580.096 bits (1494), Expect = 0.000e+0
Identity = 286/512 (55.86%), Postives = 379/512 (74.02%), Query Frame = 1 
Query:   94 SMSDQSVSKIWECLKRAIIEIQKKNNSGLSFEELYRNAYTMVLQKNGEQLYNGTKAVVTDHMI-KIRDEVLERLTNNFLAFLNRCWKDHITAMVMIRDILMYMDRVYVTTTDKPNVYNTGMIIFRDTVLRHEAIRRHLRVTLLDMVKRERHGEVISRLQLRDACQMLAQLGVDKLNIYEEDFENYFLEQSRDFYRSESERLLTENASNLYITQVNKIIEDEAKRARDFLNSTTEAKIVQVLNEELIKNHIESVVNTENFGLTHMLSNKKYSEIALMFNLLKRVDNGLATMCSCISRFLREEGRKIVEDD---KTPQIYIQELIYXXXXXXXXXXXXXXXXQLFKNQINSDFEFFINQNSRSPEYLSLYIDDKLKRGTKGISDQDIDAIFDKCIILFRYLQDKDIFERYYKQHLAKRLLMSKSQSDDQEKSMISKLLIECGGVFTSKLEGMFKDMAISKTLMEEFHSQLQMYTTNTLGIDLFVRVLTTGLWPTQTATQTVCMPDEAQNAFSIY 1617
            +M ++ V+ IW+ LK AI EIQ+KNNSGLSFEELYRNAYTMVL K+GE+LY G + VVT+H+I K+R++VL  L NNFL  LN+ W DH TAMVMIRDILMYMDRVYV   +  NVYN G+IIFRD V+R+  IR HLR TLLDM+ RER GEV+ R  +R+ACQML  LG++  ++YEEDFE  FLE S +F++ ES++ L EN++++YI +V   I +E +R    L+ +TE  IV+V+  ELI  H++++V  EN GL HML N K  ++A M+ L  RV NGL TMC C+S +LRE+G+ +V ++   K P  YIQ L+ L+ R +  L  +  N++LFK  I  DFE+F+N NSRSPEYLSL+IDDKLK+G KG+++Q++++I DK ++LFR++Q+KD+FERYYKQHLA+RLL +KS SDD EK+MISKL  ECG  FTSKLEGMF+DM+IS T M+EF   LQ    +  G+DL VRVLTTG WPTQ+AT    +P   ++AF I+
Sbjct:   26 TMDEKYVNSIWDLLKNAIQEIQRKNNSGLSFEELYRNAYTMVLHKHGEKLYTGLREVVTEHLINKVREDVLNSLNNNFLQTLNQAWNDHQTAMVMIRDILMYMDRVYVQQNNVENVYNLGLIIFRDQVVRYGCIRDHLRQTLLDMIARERKGEVVDRGAIRNACQMLMILGLEGRSVYEEDFEAPFLEMSAEFFQMESQKFLAENSASVYIKKVEARINEEIERVMHCLDKSTEEPIVKVVERELISKHMKTIVEMENSGLVHMLKNGKTEDLACMYKLFSRVPNGLKTMCECMSLYLREQGKALVSEEGEGKNPVDYIQGLLDLKSRFDRFLQESFSNDRLFKQTIAGDFEYFLNLNSRSPEYLSLFIDDKLKKGVKGLTEQEVESILDKAMVLFRFMQEKDVFERYYKQHLARRLLTNKSVSDDSEKNMISKLKTECGCQFTSKLEGMFRDMSISNTTMDEFRQHLQTTGVSLGGVDLTVRVLTTGYWPTQSATPKCNIPPAPRHAFEIF 537
[Close]
BLAST of Cullin 3 vs. Ensembl Xenopus
Match: cul3 (cullin 3 [Source:NCBI gene;Acc:548729])

HSP 1 Score: 579.711 bits (1493), Expect = 0.000e+0
Identity = 286/512 (55.86%), Postives = 379/512 (74.02%), Query Frame = 1 
Query:   94 SMSDQSVSKIWECLKRAIIEIQKKNNSGLSFEELYRNAYTMVLQKNGEQLYNGTKAVVTDHMI-KIRDEVLERLTNNFLAFLNRCWKDHITAMVMIRDILMYMDRVYVTTTDKPNVYNTGMIIFRDTVLRHEAIRRHLRVTLLDMVKRERHGEVISRLQLRDACQMLAQLGVDKLNIYEEDFENYFLEQSRDFYRSESERLLTENASNLYITQVNKIIEDEAKRARDFLNSTTEAKIVQVLNEELIKNHIESVVNTENFGLTHMLSNKKYSEIALMFNLLKRVDNGLATMCSCISRFLREEGRKIVEDD---KTPQIYIQELIYXXXXXXXXXXXXXXXXQLFKNQINSDFEFFINQNSRSPEYLSLYIDDKLKRGTKGISDQDIDAIFDKCIILFRYLQDKDIFERYYKQHLAKRLLMSKSQSDDQEKSMISKLLIECGGVFTSKLEGMFKDMAISKTLMEEFHSQLQMYTTNTLGIDLFVRVLTTGLWPTQTATQTVCMPDEAQNAFSIY 1617
            +M ++ V+ IW+ LK AI EIQ+KNNSGLSFEELYRNAYTMVL K+GE+LY G + VVT+H+I K+R++VL  L NNFL  LN+ W DH TAMVMIRDILMYMDRVYV   +  NVYN G+IIFRD V+R+  IR HLR TLLDM+ RER GEV+ R  +R+ACQML  LG++  ++YEEDFE  FLE S +F++ ES++ L EN++++YI +V   I +E +R    L+ +TE  IV+V+  ELI  H++++V  EN GL HML N K  ++A M+ L  RV NGL TMC C+S +LRE+G+ +V ++   K P  YIQ L+ L+ R +  L  +  N++LFK  I  DFE+F+N NSRSPEYLSL+IDDKLK+G KG+++Q++++I DK ++LFR++Q+KD+FERYYKQHLA+RLL +KS SDD EK+MISKL  ECG  FTSKLEGMF+DM+IS T M+EF   LQ    +  G+DL VRVLTTG WPTQ+AT    +P   ++AF I+
Sbjct:   26 TMDEKYVNSIWDLLKNAIQEIQRKNNSGLSFEELYRNAYTMVLHKHGEKLYTGLREVVTEHLINKVREDVLNSLNNNFLQTLNQAWNDHQTAMVMIRDILMYMDRVYVQQNNVENVYNLGLIIFRDQVVRYGCIRDHLRQTLLDMIARERKGEVVDRGAIRNACQMLMILGLEGRSVYEEDFEAPFLEMSAEFFQMESQKFLAENSASVYIKKVEARINEEIERVMHCLDKSTEEPIVKVVERELISKHMKTIVEMENSGLVHMLKNGKTEDLACMYKLFSRVPNGLKTMCECMSLYLREQGKALVSEEGEGKNPVDYIQGLLDLKSRFDRFLQESFSNDRLFKQTIAGDFEYFLNLNSRSPEYLSLFIDDKLKKGVKGLTEQEVESILDKAMVLFRFMQEKDVFERYYKQHLARRLLTNKSVSDDSEKNMISKLKTECGCQFTSKLEGMFRDMSISNTTMDEFRQHLQTTGVSLGGVDLTVRVLTTGYWPTQSATPKCNIPPAPRHAFEIF 537
[Close]
BLAST of Cullin 3 vs. Ensembl Xenopus
Match: cul3 (cullin 3 [Source:NCBI gene;Acc:548729])

HSP 1 Score: 495.738 bits (1275), Expect = 1.159e-168
Identity = 243/447 (54.36%), Postives = 325/447 (72.71%), Query Frame = 1 
Query:  286 IRDEVLERLTNNFLAFLNRCWKDHITAMVMIRDILMYMDRVYVTTTDKPNVYNTGMIIFRDTVLRHEAIRRHLRVTLLDMVKRERHGEVISRLQLRDACQMLAQLGVDKLNIYEEDFENYFLEQSRDFYRSESERLLTENASNLYITQVNKIIEDEAKRARDFLNSTTEAKIVQVLNEELIKNHIESVVNTENFGLTHMLSNKKYSEIALMFNLLKRVDNGLATMCSCISRFLREEGRKIVEDD---KTPQIYIQELIYXXXXXXXXXXXXXXXXQLFKNQINSDFEFFINQNSRSPEYLSLYIDDKLKRGTKGISDQDIDAIFDKCIILFRYLQDKDIFERYYKQHLAKRLLMSKSQSDDQEKSMISKLLIECGGVFTSKLEGMFKDMAISKTLMEEFHSQLQMYTTNTLGIDLFVRVLTTGLWPTQTATQTVCMPDEAQNAFSIY 1617
            +R++VL  L NNFL  LN+ W DH TAMVMIRDILMYMDRVYV   +  NVYN G+IIFRD V+R+  IR HLR TLLDM+ RER GEV+ R  +R+ACQML  LG++  ++YEEDFE  FLE S +F++ ES++ L EN++++YI +V   I +E +R    L+ +TE  IV+V+  ELI  H++++V  EN GL HML N K  ++A M+ L  RV NGL TMC C+S +LRE+G+ +V ++   K P  YIQ L+ L+ R +  L  +  N++LFK  I  DFE+F+N NSRSPEYLSL+IDDKLK+G KG+++Q++++I DK ++LFR++Q+KD+FERYYKQHLA+RLL +KS SDD EK+MISKL  ECG  FTSKLEGMF+DM+IS T M+EF   LQ    +  G+DL VRVLTTG WPTQ+AT    +P   ++AF I+
Sbjct:   23 VREDVLNSLNNNFLQTLNQAWNDHQTAMVMIRDILMYMDRVYVQQNNVENVYNLGLIIFRDQVVRYGCIRDHLRQTLLDMIARERKGEVVDRGAIRNACQMLMILGLEGRSVYEEDFEAPFLEMSAEFFQMESQKFLAENSASVYIKKVEARINEEIERVMHCLDKSTEEPIVKVVERELISKHMKTIVEMENSGLVHMLKNGKTEDLACMYKLFSRVPNGLKTMCECMSLYLREQGKALVSEEGEGKNPVDYIQGLLDLKSRFDRFLQESFSNDRLFKQTIAGDFEYFLNLNSRSPEYLSLFIDDKLKKGVKGLTEQEVESILDKAMVLFRFMQEKDVFERYYKQHLARRLLTNKSVSDDSEKNMISKLKTECGCQFTSKLEGMFRDMSISNTTMDEFRQHLQTTGVSLGGVDLTVRVLTTGYWPTQSATPKCNIPPAPRHAFEIF 469
[Close]
BLAST of Cullin 3 vs. Ensembl Xenopus
Match: cul4a (cullin 4A [Source:NCBI gene;Acc:548647])

HSP 1 Score: 290.812 bits (743), Expect = 1.762e-89
Identity = 176/524 (33.59%), Postives = 285/524 (54.39%), Query Frame = 1 
Query:   43 SSVSSNPS---KMRIKAFP--TSMSDQSVSKIWECLKRAIIEIQKKNNSGLSFEELYRNAYTMVLQKNGEQLYNGTKAVVTDHMIKIRDEVLERLTNNFLAFLNRCWKDHITAMVMIRDILMYMDRVYVTTTDK-PNVYNTGMIIFRDTVLRHEAIRRHLRVTLLDMVKRERHGEVISRLQLRDACQMLAQLGVDKLNIYEEDFENYFLEQSRDFYRSESERLLTENASNLYITQVNKIIEDEAKRARDFLNSTTEAKIVQVLNEELIKNHIESVVNTENFGLTHMLSNKKYSEIALMFNLLKRVDNGLATMCSCISRFLREEGRKIVEDDKTPQIYIQELIYXXXXXXXXXXXXXXXXQLFKNQINSDFEFFINQNSRSP-EYLSLYIDDKLKRGTKGISDQDIDAIFDKCIILFRYLQDKDIFERYYKQHLAKRLLMSKSQSDDQEKSMISKLLIECGGVFTSKLEGMFKDMAISKTLMEEFHSQLQMYTTNTLGIDLFVRVLTTGLWPTQTATQTVCMPDE 1593
            S+++S PS   K+ IK F     + D      W+ L+ A+  I+   +   + EELY+    +   K    LY   + V  +HM       L      FL  +NRCWKDH   M+MIR I +++DR YV      P++++ G+ +FR  V+    ++      +L ++++ER GE + R  LR    ML+ L      +Y+E FE  FLE++   Y +E +RL+ E     Y+  VN+ +E+E  R   +L+  T   ++  + ++L+  H+ +++     GL +ML   +  E+ LM+ L  RV  G   +      +++  G  +V + +  +  +QEL+  +D  + ++      N+ F N +   FE FIN+ +  P E ++ Y+D KL+ G K  +D++++ + DK +I+FR++  KD+FE +YK+ LAKRLL+ KS S D EKSM+SKL  ECG  FTSKLEGMFKDM +SK +M +F   +Q + ++   IDL V +LT G WPT T    V +P E
Sbjct:   25 SALTSKPSASKKLIIKNFKDKPKLPDSYTQDTWQKLQEAVNAIESSTSIKYNLEELYQAVENLCSYKVSHTLYKQLRQVCEEHMKAQIHHFL------FLKKVNRCWKDHCRQMIMIRSIFLFLDRTYVLQNSMLPSIWDMGLELFRCHVVSDRMVQIKTIDGILKLIEQERSGEAVDRSLLRSLLGMLSDL-----QVYKESFETKFLEETNCLYAAEGQRLMQEREVPEYLHHVNRRLEEEVDRVITYLDHGTHKPLIACVEKQLLGEHLTAILQK---GLKNMLDENRDPELTLMYQLFSRVKGGQIILLQHWGEYIKNFGSGLVINPEKDKDMVQELLDFKDNVDHIIDVCFQKNEKFVNTMKESFETFINRRANKPAELIAKYVDSKLRSGNKEATDEELERLLDKIMIIFRFIHGKDVFEAFYKKDLAKRLLVGKSASVDSEKSMLSKLKHECGAAFTSKLEGMFKDMELSKDVMVQFKQHMQNH-SDPGNIDLTVNILTMGYWPTYTPVD-VHLPAE 532
[Close]
BLAST of Cullin 3 vs. Ensembl Mouse
Match: Cul3 (cullin 3 [Source:MGI Symbol;Acc:MGI:1347360])

HSP 1 Score: 596.275 bits (1536), Expect = 0.000e+0
Identity = 294/526 (55.89%), Postives = 388/526 (73.76%), Query Frame = 1 
Query:   52 SSNPSKMRIKAFPTSMSDQSVSKIWECLKRAIIEIQKKNNSGLSFEELYRNAYTMVLQKNGEQLYNGTKAVVTDHMI-KIRDEVLERLTNNFLAFLNRCWKDHITAMVMIRDILMYMDRVYVTTTDKPNVYNTGMIIFRDTVLRHEAIRRHLRVTLLDMVKRERHGEVISRLQLRDACQMLAQLGVDKLNIYEEDFENYFLEQSRDFYRSESERLLTENASNLYITQVNKIIEDEAKRARDFLNSTTEAKIVQVLNEELIKNHIESVVNTENFGLTHMLSNKKYSEIALMFNLLKRVDNGLATMCSCISRFLREEGRKIVEDD---KTPQIYIQELIYXXXXXXXXXXXXXXXXQLFKNQINSDFEFFINQNSRSPEYLSLYIDDKLKRGTKGISDQDIDAIFDKCIILFRYLQDKDIFERYYKQHLAKRLLMSKSQSDDQEKSMISKLLIECGGVFTSKLEGMFKDMAISKTLMEEFHSQLQMYTTNTLGIDLFVRVLTTGLWPTQTATQTVCMPDEAQNAFSIY 1617
            S   +KMRI+AFP +M ++ V+ IW+ LK AI EIQ+KNNSGLSFEELYRNAYTMVL K+GE+LY G + VVT+H+I K+R++VL  L NNFL  LN+ W DH TAMVMIRDILMYMDRVYV   +  NVYN G+IIFRD V+R+  IR HLR TLLDM+ RER GEV+ R  +R+ACQML  LG++  ++YEEDFE  FLE S +F++ ES++ L EN++++YI +V   I +E +R    L+ +TE  IV+V+  ELI  H++++V  EN GL HML N K  ++A M+ L  RV NGL TMC C+S +LRE+G+ +V ++   K P  YIQ L+ L+ R +  L  +  N++LFK  I  DFE+F+N NSRSPEYLSL+IDDKLK+G KG+++Q+++ I DK ++LFR++Q+KD+FERYYKQHLA+RLL +KS SDD EK+MISKL  ECG  FTSKLEGMF+DM+IS T M+EF   LQ    +  G+DL VRVLTTG WPTQ+AT    +P   ++AF I+
Sbjct:   10 SRKDTKMRIRAFPMTMDEKYVNSIWDLLKNAIQEIQRKNNSGLSFEELYRNAYTMVLHKHGEKLYTGLREVVTEHLINKVREDVLNSLNNNFLQTLNQAWNDHQTAMVMIRDILMYMDRVYVQQNNVENVYNLGLIIFRDQVVRYGCIRDHLRQTLLDMIARERKGEVVDRGAIRNACQMLMILGLEGRSVYEEDFEAPFLEMSAEFFQMESQKFLAENSASVYIKKVEARINEEIERVMHCLDKSTEEPIVKVVERELISKHMKTIVEMENSGLVHMLKNGKTEDLACMYKLFSRVPNGLKTMCECMSCYLREQGKALVSEEGEGKNPVDYIQGLLDLKSRFDRFLQESFNNDRLFKQTIAGDFEYFLNLNSRSPEYLSLFIDDKLKKGVKGLTEQEVETILDKAMVLFRFMQEKDVFERYYKQHLARRLLTNKSVSDDSEKNMISKLKTECGCQFTSKLEGMFRDMSISNTTMDEFRQHLQATGVSLGGVDLTVRVLTTGYWPTQSATPKCNIPPAPRHAFEIF 535
[Close]
BLAST of Cullin 3 vs. Ensembl Mouse
Match: Cul3 (cullin 3 [Source:MGI Symbol;Acc:MGI:1347360])

HSP 1 Score: 493.812 bits (1270), Expect = 4.133e-168
Identity = 243/447 (54.36%), Postives = 324/447 (72.48%), Query Frame = 1 
Query:  286 IRDEVLERLTNNFLAFLNRCWKDHITAMVMIRDILMYMDRVYVTTTDKPNVYNTGMIIFRDTVLRHEAIRRHLRVTLLDMVKRERHGEVISRLQLRDACQMLAQLGVDKLNIYEEDFENYFLEQSRDFYRSESERLLTENASNLYITQVNKIIEDEAKRARDFLNSTTEAKIVQVLNEELIKNHIESVVNTENFGLTHMLSNKKYSEIALMFNLLKRVDNGLATMCSCISRFLREEGRKIVEDD---KTPQIYIQELIYXXXXXXXXXXXXXXXXQLFKNQINSDFEFFINQNSRSPEYLSLYIDDKLKRGTKGISDQDIDAIFDKCIILFRYLQDKDIFERYYKQHLAKRLLMSKSQSDDQEKSMISKLLIECGGVFTSKLEGMFKDMAISKTLMEEFHSQLQMYTTNTLGIDLFVRVLTTGLWPTQTATQTVCMPDEAQNAFSIY 1617
            +R++VL  L NNFL  LN+ W DH TAMVMIRDILMYMDRVYV   +  NVYN G+IIFRD V+R+  IR HLR TLLDM+ RER GEV+ R  +R+ACQML  LG++  ++YEEDFE  FLE S +F++ ES++ L EN++++YI +V   I +E +R    L+ +TE  IV+V+  ELI  H++++V  EN GL HML N K  ++A M+ L  RV NGL TMC C+S +LRE+G+ +V ++   K P  YIQ L+ L+ R +  L  +  N++LFK  I  DFE+F+N NSRSPEYLSL+IDDKLK+G KG+++Q+++ I DK ++LFR++Q+KD+FERYYKQHLA+RLL +KS SDD EK+MISKL  ECG  FTSKLEGMF+DM+IS T M+EF   LQ    +  G+DL VRVLTTG WPTQ+AT    +P   ++AF I+
Sbjct:   23 VREDVLNSLNNNFLQTLNQAWNDHQTAMVMIRDILMYMDRVYVQQNNVENVYNLGLIIFRDQVVRYGCIRDHLRQTLLDMIARERKGEVVDRGAIRNACQMLMILGLEGRSVYEEDFEAPFLEMSAEFFQMESQKFLAENSASVYIKKVEARINEEIERVMHCLDKSTEEPIVKVVERELISKHMKTIVEMENSGLVHMLKNGKTEDLACMYKLFSRVPNGLKTMCECMSCYLREQGKALVSEEGEGKNPVDYIQGLLDLKSRFDRFLQESFNNDRLFKQTIAGDFEYFLNLNSRSPEYLSLFIDDKLKKGVKGLTEQEVETILDKAMVLFRFMQEKDVFERYYKQHLARRLLTNKSVSDDSEKNMISKLKTECGCQFTSKLEGMFRDMSISNTTMDEFRQHLQATGVSLGGVDLTVRVLTTGYWPTQSATPKCNIPPAPRHAFEIF 469
[Close]
BLAST of Cullin 3 vs. Ensembl Mouse
Match: Cul4a (cullin 4A [Source:MGI Symbol;Acc:MGI:1914487])

HSP 1 Score: 273.092 bits (697), Expect = 2.648e-82
Identity = 174/534 (32.58%), Postives = 288/534 (53.93%), Query Frame = 1 
Query:   16 MSGNIRKLDSSVSSNPSKMRIKAFP--TSMSDQSVSKIWECLKRAIIEIQKKNNSGLSFEELYRNAYTMVLQKNGEQLYNGTKAVVTDH----MIKIRDEVLERLTNNFLAFLNRCWKDHITAMVMIRDILMYMDRVYVTTTDK-PNVYNTGMIIFRDTVLRHEAIRRHLRVTLLDMVKRERHGEVISRLQLRDACQMLAQLGVDKLNIYEEDFENYFLEQSRDFYRSESERLLTENASNLYITQVNKIIEDEAKRARDFLNSTTEAKIVQVLNEELIKNHIESVVNTENFGLTHMLSNKKYSEIALMFNLLKRVDNGLATMCSCISRFLREEGRKIVEDDKTPQIYIQELIYXXXXXXXXXXXXXXXXQLFKNQINSDFEFFINQNSRSP-EYLSLYIDDKLKRGTKGISDQDIDAIFDKCIILFRYLQDKDIFERYYKQHLAKRLLMSKSQSDDQEKSMISKLLIECGGVFTSKLEGMFKDMAISKTLMEEFHSQLQMYTTNTLGIDLFVRVLTTGLWPTQTATQTVCMPDE 1593
            ++G   K   +  S   K+ IK F     + D      W  L  A+  IQ   +   + EELY+    +   K    LY   + V  DH    ++  R++ L+ +   FL  +N CW+DH   M+MIR I +++DR YV      P++++ G+ +FR+ ++    ++      +L ++ RER GE + R  LR    ML+ L      +Y++ FE  FLE++   Y +E +RL+ +     Y+  V+K +E+EA R   +L+ +T+  ++  + ++L+  H+ +++     GL H+L   +  ++  M+ L  RV  G   +    S +++  G  IV + +  +  +Q+L+  +D+ + ++      N+ F N +   FE FIN+    P E ++ ++D KL+ G K  +D++++ I DK +ILFR++  KD+FE +YK+ LAKRLL+ KS S D EKSM+SKL  ECG  FTSKLEGMFKDM +SK +M  F   +Q  +     IDL V +LT G WPT T  + V +P E
Sbjct:   27 LAGGPAKPGGTGGSR--KLVIKNFRDRPRLPDNYTQDTWRKLHEAVKAIQSSTSIRYNLEELYQAVENLCSHKVSPTLYKQLRQVCEDHVQAQILPFREDSLDSVL--FLKKINTCWQDHCRQMIMIRSIFLFLDRTYVLQNSMLPSIWDMGLELFRNHIISDRMVQSKTIDGILLLIGRERSGEAVDRSLLRSLLSMLSDL-----QVYKDSFELKFLEETNCLYAAEGQRLMQDREVPEYLNHVSKRLEEEADRVITYLDHSTQKPLIACVEKQLLGEHLTAILQK---GLEHLLDENRVPDLTQMYQLFSRVKGGQHALLQHWSEYIKTFGTTIVINPEKDKDMVQDLLDFKDKVDHVVEVCFQRNERFINLMKESFETFINKRPNKPAELIAKHVDSKLRAGNKEATDEELERILDKIMILFRFIHGKDVFEAFYKKDLAKRLLVGKSASVDAEKSMLSKLKHECGAAFTSKLEGMFKDMELSKDIMVHFKQHMQNQSAPG-PIDLTVNILTMGYWPTYTPME-VHLPPE 546
[Close]
BLAST of Cullin 3 vs. Ensembl Mouse
Match: Cul4b (cullin 4B [Source:MGI Symbol;Acc:MGI:1919834])

HSP 1 Score: 273.092 bits (697), Expect = 2.766e-81
Identity = 175/538 (32.53%), Postives = 299/538 (55.58%), Query Frame = 1 
Query:   19 SGNIRKLDSSVSSNPSKMRIKAF------PTSMSDQSVSKIWECLKRAIIEIQKKNNSGLSFEELYRNAYTMVLQKNGEQLYNGTKAVVTDHMI----KIRDEVLERLTNNFLAFLNRCWKDHITAMVMIRDILMYMDRVYVTTTDK-PNVYNTGMIIFRDTVLRHEAIRRHLRVTLLDMVKRERHGEVISRLQLRDACQMLAQLGVDKLNIYEEDFENYFLEQSRDFYRSESERLLTENASNLYITQVNKIIEDEAKRARDFLNSTTEAKIVQVLNEELIKNHIESVVNTENFGLTHMLSNKKYSEIALMFNLLKRVDNGLATMCSCISRFLREEGRKIVEDDKTPQIYIQELIYXXXXXXXXXXXXXXXXQLFKNQINSDFEFFINQNSRSP-EYLSLYIDDKLKRGTKGISDQDIDAIFDKCIILFRYLQDKDIFERYYKQHLAKRLLMSKSQSDDQEKSMISKLLIECGGVFTSKLEGMFKDMAISKTLMEEFHSQLQMYTTNTLG-IDLFVRVLTTGLWPTQTATQTVCMPDE 1593
            S  +    +S   +  K+ IK F      P + +D++    W+ LK A+  IQ   +   + EELY+    +   K    LY   + +  DH+     + R++ L+ +   FL  ++RCW++H   M+MIR I +++DR YV      P++++ G+ +FR  ++  + ++      +L +++RER+GE I R  LR    ML+ L      IY++ FE  FL+++   Y +E ++L+ E     Y+  VNK +E+EA R   +L+ TT+  ++  + ++L+  H+ +++     GL  +L   +  +++L++ L  RV  G+  +      +++  G  IV + +  +  +QEL+  +D+ + ++    L N+ F N +   FE FIN+    P E ++ Y+D KL+ G K  +D++++ + DK +I+FR++  KD+FE +YK+ LAKRLL+ KS S D EKSM+SKL  ECG  FTSKLEGMFKDM +SK +M +F   +Q    N  G I+L V +LT G WPT    + V +P E
Sbjct:  163 STAVSSFANSKPGSAKKLVIKNFKDKPKLPENYTDET----WQKLKEAVEAIQNSTSIKYNLEELYQAVENLCSHKISANLYKQLRQICEDHIKAQIHQFREDSLDSVL--FLKKIDRCWQNHCRQMIMIRSIFLFLDRTYVLQNSMLPSIWDMGLELFRAHIISDQKVQTKTIDGILLLIERERNGEAIDRSLLRSLLSMLSDL-----QIYQDSFEQQFLQETNRLYAAEGQKLMQEREVPEYLHHVNKRLEEEADRLITYLDQTTQKSLIASVEKQLLGEHLTAILQK---GLNSLLDENRIQDLSLLYQLFSRVRGGVQVLLQQWIEYIKAFGSTIVINPEKDKTMVQELLDFKDKVDHIIDTCFLKNEKFINAMKEAFETFINKRPNKPAELIAKYVDSKLRAGNKEATDEELEKMLDKIMIIFRFIYGKDVFEAFYKKDLAKRLLVGKSASVDAEKSMLSKLKHECGAAFTSKLEGMFKDMELSKDIMIQFKQYMQ--NQNVPGNIELTVNILTMGYWPTYVPME-VHLPPE 683
[Close]
BLAST of Cullin 3 vs. Ensembl Mouse
Match: Cul4b (cullin 4B [Source:MGI Symbol;Acc:MGI:1919834])

HSP 1 Score: 271.937 bits (694), Expect = 1.786e-80
Identity = 175/538 (32.53%), Postives = 299/538 (55.58%), Query Frame = 1 
Query:   19 SGNIRKLDSSVSSNPSKMRIKAF------PTSMSDQSVSKIWECLKRAIIEIQKKNNSGLSFEELYRNAYTMVLQKNGEQLYNGTKAVVTDHMI----KIRDEVLERLTNNFLAFLNRCWKDHITAMVMIRDILMYMDRVYVTTTDK-PNVYNTGMIIFRDTVLRHEAIRRHLRVTLLDMVKRERHGEVISRLQLRDACQMLAQLGVDKLNIYEEDFENYFLEQSRDFYRSESERLLTENASNLYITQVNKIIEDEAKRARDFLNSTTEAKIVQVLNEELIKNHIESVVNTENFGLTHMLSNKKYSEIALMFNLLKRVDNGLATMCSCISRFLREEGRKIVEDDKTPQIYIQELIYXXXXXXXXXXXXXXXXQLFKNQINSDFEFFINQNSRSP-EYLSLYIDDKLKRGTKGISDQDIDAIFDKCIILFRYLQDKDIFERYYKQHLAKRLLMSKSQSDDQEKSMISKLLIECGGVFTSKLEGMFKDMAISKTLMEEFHSQLQMYTTNTLG-IDLFVRVLTTGLWPTQTATQTVCMPDE 1593
            S  +    +S   +  K+ IK F      P + +D++    W+ LK A+  IQ   +   + EELY+    +   K    LY   + +  DH+     + R++ L+ +   FL  ++RCW++H   M+MIR I +++DR YV      P++++ G+ +FR  ++  + ++      +L +++RER+GE I R  LR    ML+ L      IY++ FE  FL+++   Y +E ++L+ E     Y+  VNK +E+EA R   +L+ TT+  ++  + ++L+  H+ +++     GL  +L   +  +++L++ L  RV  G+  +      +++  G  IV + +  +  +QEL+  +D+ + ++    L N+ F N +   FE FIN+    P E ++ Y+D KL+ G K  +D++++ + DK +I+FR++  KD+FE +YK+ LAKRLL+ KS S D EKSM+SKL  ECG  FTSKLEGMFKDM +SK +M +F   +Q    N  G I+L V +LT G WPT    + V +P E
Sbjct:  237 STAVSSFANSKPGSAKKLVIKNFKDKPKLPENYTDET----WQKLKEAVEAIQNSTSIKYNLEELYQAVENLCSHKISANLYKQLRQICEDHIKAQIHQFREDSLDSVL--FLKKIDRCWQNHCRQMIMIRSIFLFLDRTYVLQNSMLPSIWDMGLELFRAHIISDQKVQTKTIDGILLLIERERNGEAIDRSLLRSLLSMLSDL-----QIYQDSFEQQFLQETNRLYAAEGQKLMQEREVPEYLHHVNKRLEEEADRLITYLDQTTQKSLIASVEKQLLGEHLTAILQK---GLNSLLDENRIQDLSLLYQLFSRVRGGVQVLLQQWIEYIKAFGSTIVINPEKDKTMVQELLDFKDKVDHIIDTCFLKNEKFINAMKEAFETFINKRPNKPAELIAKYVDSKLRAGNKEATDEELEKMLDKIMIIFRFIYGKDVFEAFYKKDLAKRLLVGKSASVDAEKSMLSKLKHECGAAFTSKLEGMFKDMELSKDIMIQFKQYMQ--NQNVPGNIELTVNILTMGYWPTYVPME-VHLPPE 757
[Close]
BLAST of Cullin 3 vs. UniProt/SwissProt
Match: sp|Q6GPF3|CUL3B_XENLA (Cullin-3-B OS=Xenopus laevis OX=8355 GN=cul3b PE=1 SV=1)

HSP 1 Score: 598.971 bits (1543), Expect = 0.000e+0
Identity = 295/529 (55.77%), Postives = 391/529 (73.91%), Query Frame = 1 
Query:   43 SSVSSNPSKMRIKAFPTSMSDQSVSKIWECLKRAIIEIQKKNNSGLSFEELYRNAYTMVLQKNGEQLYNGTKAVVTDHMI-KIRDEVLERLTNNFLAFLNRCWKDHITAMVMIRDILMYMDRVYVTTTDKPNVYNTGMIIFRDTVLRHEAIRRHLRVTLLDMVKRERHGEVISRLQLRDACQMLAQLGVDKLNIYEEDFENYFLEQSRDFYRSESERLLTENASNLYITQVNKIIEDEAKRARDFLNSTTEAKIVQVLNEELIKNHIESVVNTENFGLTHMLSNKKYSEIALMFNLLKRVDNGLATMCSCISRFLREEGRKIVEDD---KTPQIYIQELIYXXXXXXXXXXXXXXXXQLFKNQINSDFEFFINQNSRSPEYLSLYIDDKLKRGTKGISDQDIDAIFDKCIILFRYLQDKDIFERYYKQHLAKRLLMSKSQSDDQEKSMISKLLIECGGVFTSKLEGMFKDMAISKTLMEEFHSQLQMYTTNTLGIDLFVRVLTTGLWPTQTATQTVCMPDEAQNAFSIY 1617
            S+ S   +KMRI+AFP +M ++ V+ IW+ LK AI EIQ+KNNSGLSFEELYRNAYTMVL K+GE+LY G + VVT+H+I K+R++VL  L NNFL  LN+ W DH TAMVMIRDILMYMDRVYV   +  NVYN G+IIFRD V+R+  IR HLR TLLDM+ RER GEV+ R  +R+ACQML  LG++  ++YEEDFE  FLE S +F++ ES++ L EN++++YI +V   I +E +R    L+ +TE  IV+V+  ELI  H++++V  EN GL HML N K  ++A M+ L  RV NGL TMC C+S +LRE+G+ +V ++   K P  YIQ L+ L+ R +  L  +  N++LFK  I  DFE+F+N NSRSPEYLSL+IDDKLK+G KG+++Q++++I DK ++LFR++Q+KD+FERYYKQHLA+RLL +KS SDD EK+MISKL  ECG  FTSKLEGMF+DM+IS T M+EF   LQ    +  G+DL VRVLTTG WPTQ+AT    +P   ++AF I+
Sbjct:    7 STGSRKDTKMRIRAFPMTMDEKYVNSIWDLLKNAIQEIQRKNNSGLSFEELYRNAYTMVLHKHGEKLYTGLREVVTEHLINKVREDVLNSLNNNFLQTLNQAWNDHQTAMVMIRDILMYMDRVYVQQNNVENVYNLGLIIFRDQVVRYGCIRDHLRQTLLDMIARERKGEVVDRGAIRNACQMLMILGLEGRSVYEEDFEAPFLEMSAEFFQMESQKFLAENSASVYIKKVEARINEEIERVMHCLDKSTEEPIVKVVERELISKHMKTIVEMENSGLVHMLKNGKTEDLACMYKLFSRVPNGLKTMCECMSLYLREQGKALVSEEGEGKNPVDYIQGLLDLKSRFDRFLQESFSNDRLFKQTIAGDFEYFLNLNSRSPEYLSLFIDDKLKKGVKGLTEQEVESILDKAMVLFRFMQEKDVFERYYKQHLARRLLTNKSVSDDSEKNMISKLKTECGCQFTSKLEGMFRDMSISNTTMDEFRQHLQTTGVSLGGVDLTVRVLTTGYWPTQSATPKCNIPPSPRHAFEIF 535
[Close]
BLAST of Cullin 3 vs. UniProt/SwissProt
Match: sp|A4IHP4|CUL3_XENTR (Cullin-3 OS=Xenopus tropicalis OX=8364 GN=cul3 PE=2 SV=1)

HSP 1 Score: 598.586 bits (1542), Expect = 0.000e+0
Identity = 295/529 (55.77%), Postives = 391/529 (73.91%), Query Frame = 1 
Query:   43 SSVSSNPSKMRIKAFPTSMSDQSVSKIWECLKRAIIEIQKKNNSGLSFEELYRNAYTMVLQKNGEQLYNGTKAVVTDHMI-KIRDEVLERLTNNFLAFLNRCWKDHITAMVMIRDILMYMDRVYVTTTDKPNVYNTGMIIFRDTVLRHEAIRRHLRVTLLDMVKRERHGEVISRLQLRDACQMLAQLGVDKLNIYEEDFENYFLEQSRDFYRSESERLLTENASNLYITQVNKIIEDEAKRARDFLNSTTEAKIVQVLNEELIKNHIESVVNTENFGLTHMLSNKKYSEIALMFNLLKRVDNGLATMCSCISRFLREEGRKIVEDD---KTPQIYIQELIYXXXXXXXXXXXXXXXXQLFKNQINSDFEFFINQNSRSPEYLSLYIDDKLKRGTKGISDQDIDAIFDKCIILFRYLQDKDIFERYYKQHLAKRLLMSKSQSDDQEKSMISKLLIECGGVFTSKLEGMFKDMAISKTLMEEFHSQLQMYTTNTLGIDLFVRVLTTGLWPTQTATQTVCMPDEAQNAFSIY 1617
            S+ S   +KMRI+AFP +M ++ V+ IW+ LK AI EIQ+KNNSGLSFEELYRNAYTMVL K+GE+LY G + VVT+H+I K+R++VL  L NNFL  LN+ W DH TAMVMIRDILMYMDRVYV   +  NVYN G+IIFRD V+R+  IR HLR TLLDM+ RER GEV+ R  +R+ACQML  LG++  ++YEEDFE  FLE S +F++ ES++ L EN++++YI +V   I +E +R    L+ +TE  IV+V+  ELI  H++++V  EN GL HML N K  ++A M+ L  RV NGL TMC C+S +LRE+G+ +V ++   K P  YIQ L+ L+ R +  L  +  N++LFK  I  DFE+F+N NSRSPEYLSL+IDDKLK+G KG+++Q++++I DK ++LFR++Q+KD+FERYYKQHLA+RLL +KS SDD EK+MISKL  ECG  FTSKLEGMF+DM+IS T M+EF   LQ    +  G+DL VRVLTTG WPTQ+AT    +P   ++AF I+
Sbjct:    7 STGSRKDTKMRIRAFPMTMDEKYVNSIWDLLKNAIQEIQRKNNSGLSFEELYRNAYTMVLHKHGEKLYTGLREVVTEHLINKVREDVLNSLNNNFLQTLNQAWNDHQTAMVMIRDILMYMDRVYVQQNNVENVYNLGLIIFRDQVVRYGCIRDHLRQTLLDMIARERKGEVVDRGAIRNACQMLMILGLEGRSVYEEDFEAPFLEMSAEFFQMESQKFLAENSASVYIKKVEARINEEIERVMHCLDKSTEEPIVKVVERELISKHMKTIVEMENSGLVHMLKNGKTEDLACMYKLFSRVPNGLKTMCECMSLYLREQGKALVSEEGEGKNPVDYIQGLLDLKSRFDRFLQESFSNDRLFKQTIAGDFEYFLNLNSRSPEYLSLFIDDKLKKGVKGLTEQEVESILDKAMVLFRFMQEKDVFERYYKQHLARRLLTNKSVSDDSEKNMISKLKTECGCQFTSKLEGMFRDMSISNTTMDEFRQHLQTTGVSLGGVDLTVRVLTTGYWPTQSATPKCNIPPAPRHAFEIF 535
[Close]
BLAST of Cullin 3 vs. UniProt/SwissProt
Match: sp|Q6DE95|CUL3A_XENLA (Cullin-3-A OS=Xenopus laevis OX=8355 GN=cul3a PE=1 SV=1)

HSP 1 Score: 598.586 bits (1542), Expect = 0.000e+0
Identity = 295/529 (55.77%), Postives = 391/529 (73.91%), Query Frame = 1 
Query:   43 SSVSSNPSKMRIKAFPTSMSDQSVSKIWECLKRAIIEIQKKNNSGLSFEELYRNAYTMVLQKNGEQLYNGTKAVVTDHMI-KIRDEVLERLTNNFLAFLNRCWKDHITAMVMIRDILMYMDRVYVTTTDKPNVYNTGMIIFRDTVLRHEAIRRHLRVTLLDMVKRERHGEVISRLQLRDACQMLAQLGVDKLNIYEEDFENYFLEQSRDFYRSESERLLTENASNLYITQVNKIIEDEAKRARDFLNSTTEAKIVQVLNEELIKNHIESVVNTENFGLTHMLSNKKYSEIALMFNLLKRVDNGLATMCSCISRFLREEGRKIVEDD---KTPQIYIQELIYXXXXXXXXXXXXXXXXQLFKNQINSDFEFFINQNSRSPEYLSLYIDDKLKRGTKGISDQDIDAIFDKCIILFRYLQDKDIFERYYKQHLAKRLLMSKSQSDDQEKSMISKLLIECGGVFTSKLEGMFKDMAISKTLMEEFHSQLQMYTTNTLGIDLFVRVLTTGLWPTQTATQTVCMPDEAQNAFSIY 1617
            S+ S   +KMRI+AFP +M ++ V+ IW+ LK AI EIQ+KNNSGLSFEELYRNAYTMVL K+GE+LY G + VVT+H+I K+R++VL  L NNFL  LN+ W DH TAMVMIRDILMYMDRVYV   +  NVYN G+IIFRD V+R+  IR HLR TLLDM+ RER GEV+ R  +R+ACQML  LG++  ++YEEDFE  FLE S +F++ ES++ L EN++++YI +V   I +E +R    L+ +TE  IV+V+  ELI  H++++V  EN GL HML N K  ++A M+ L  RV NGL TMC C+S +LRE+G+ +V ++   K P  YIQ L+ L+ R +  L  +  N++LFK  I  DFE+F+N NSRSPEYLSL+IDDKLK+G KG+++Q++++I DK ++LFR++Q+KD+FERYYKQHLA+RLL +KS SDD EK+MISKL  ECG  FTSKLEGMF+DM+IS T M+EF   LQ    +  G+DL VRVLTTG WPTQ+AT    +P   ++AF I+
Sbjct:    7 STGSRKDTKMRIRAFPMTMDEKYVNSIWDLLKNAIQEIQRKNNSGLSFEELYRNAYTMVLHKHGEKLYTGLREVVTEHLINKVREDVLNSLNNNFLQTLNQAWNDHQTAMVMIRDILMYMDRVYVQQNNVENVYNLGLIIFRDQVVRYGCIRDHLRQTLLDMIARERKGEVVDRGAIRNACQMLMILGLEGRSVYEEDFEAPFLEMSAEFFQMESQKFLAENSASVYIKKVEARINEEIERVMHCLDKSTEEPIVKVVERELISKHMKTIVEMENSGLVHMLKNGKTEDLACMYKLFSRVPNGLKTMCECMSLYLREQGKALVSEEGEGKNPVDYIQGLLDLKSRFDRFLQESFSNDRLFKQTIAGDFEYFLNLNSRSPEYLSLFIDDKLKKGVKGLTEQEVESILDKAMVLFRFMQEKDVFERYYKQHLARRLLTNKSVSDDSEKNMISKLKTECGCQFTSKLEGMFRDMSISNTTMDEFRQHLQTTGVSLGGVDLTVRVLTTGYWPTQSATPKCNIPPAPRHAFEIF 535
[Close]
BLAST of Cullin 3 vs. UniProt/SwissProt
Match: sp|B5DF89|CUL3_RAT (Cullin-3 OS=Rattus norvegicus OX=10116 GN=Cul3 PE=1 SV=2)

HSP 1 Score: 597.045 bits (1538), Expect = 0.000e+0
Identity = 294/526 (55.89%), Postives = 388/526 (73.76%), Query Frame = 1 
Query:   52 SSNPSKMRIKAFPTSMSDQSVSKIWECLKRAIIEIQKKNNSGLSFEELYRNAYTMVLQKNGEQLYNGTKAVVTDHMI-KIRDEVLERLTNNFLAFLNRCWKDHITAMVMIRDILMYMDRVYVTTTDKPNVYNTGMIIFRDTVLRHEAIRRHLRVTLLDMVKRERHGEVISRLQLRDACQMLAQLGVDKLNIYEEDFENYFLEQSRDFYRSESERLLTENASNLYITQVNKIIEDEAKRARDFLNSTTEAKIVQVLNEELIKNHIESVVNTENFGLTHMLSNKKYSEIALMFNLLKRVDNGLATMCSCISRFLREEGRKIVEDD---KTPQIYIQELIYXXXXXXXXXXXXXXXXQLFKNQINSDFEFFINQNSRSPEYLSLYIDDKLKRGTKGISDQDIDAIFDKCIILFRYLQDKDIFERYYKQHLAKRLLMSKSQSDDQEKSMISKLLIECGGVFTSKLEGMFKDMAISKTLMEEFHSQLQMYTTNTLGIDLFVRVLTTGLWPTQTATQTVCMPDEAQNAFSIY 1617
            S   +KMRI+AFP +M ++ V+ IW+ LK AI EIQ+KNNSGLSFEELYRNAYTMVL K+GE+LY G + VVT+H+I K+R++VL  L NNFL  LN+ W DH TAMVMIRDILMYMDRVYV   +  NVYN G+IIFRD V+R+  IR HLR TLLDM+ RER GEV+ R  +R+ACQML  LG++  ++YEEDFE  FLE S +F++ ES++ L EN++++YI +V   I +E +R    L+ +TE  IV+V+  ELI  H++++V  EN GL HML N K  ++A M+ L  RV NGL TMC C+S +LRE+G+ +V ++   K P  YIQ L+ L+ R +  L  +  N++LFK  I  DFE+F+N NSRSPEYLSL+IDDKLK+G KG+++Q+++ I DK ++LFR++Q+KD+FERYYKQHLA+RLL +KS SDD EK+MISKL  ECG  FTSKLEGMF+DM+IS T M+EF   LQ    +  G+DL VRVLTTG WPTQ+AT    +P   ++AF I+
Sbjct:   10 SRKDTKMRIRAFPMTMDEKYVNSIWDLLKNAIQEIQRKNNSGLSFEELYRNAYTMVLHKHGEKLYTGLREVVTEHLINKVREDVLNSLNNNFLQTLNQAWNDHQTAMVMIRDILMYMDRVYVQQNNVENVYNLGLIIFRDQVVRYGCIRDHLRQTLLDMIARERKGEVVDRGAIRNACQMLMILGLEGRSVYEEDFEAPFLEMSAEFFQMESQKFLAENSASVYIKKVEARINEEIERVMHCLDKSTEEPIVKVVERELISKHMKTIVEMENSGLVHMLKNGKTEDLACMYKLFSRVPNGLKTMCECMSSYLREQGKALVSEEGEGKNPVDYIQGLLDLKSRFDRFLQESFNNDRLFKQTIAGDFEYFLNLNSRSPEYLSLFIDDKLKKGVKGLTEQEVETILDKAMVLFRFMQEKDVFERYYKQHLARRLLTNKSVSDDSEKNMISKLKTECGCQFTSKLEGMFRDMSISNTTMDEFRQHLQATGVSLGGVDLTVRVLTTGYWPTQSATPKCNIPPAPRHAFEIF 535
[Close]
BLAST of Cullin 3 vs. UniProt/SwissProt
Match: sp|Q9JLV5|CUL3_MOUSE (Cullin-3 OS=Mus musculus OX=10090 GN=Cul3 PE=1 SV=1)

HSP 1 Score: 596.275 bits (1536), Expect = 0.000e+0
Identity = 294/526 (55.89%), Postives = 388/526 (73.76%), Query Frame = 1 
Query:   52 SSNPSKMRIKAFPTSMSDQSVSKIWECLKRAIIEIQKKNNSGLSFEELYRNAYTMVLQKNGEQLYNGTKAVVTDHMI-KIRDEVLERLTNNFLAFLNRCWKDHITAMVMIRDILMYMDRVYVTTTDKPNVYNTGMIIFRDTVLRHEAIRRHLRVTLLDMVKRERHGEVISRLQLRDACQMLAQLGVDKLNIYEEDFENYFLEQSRDFYRSESERLLTENASNLYITQVNKIIEDEAKRARDFLNSTTEAKIVQVLNEELIKNHIESVVNTENFGLTHMLSNKKYSEIALMFNLLKRVDNGLATMCSCISRFLREEGRKIVEDD---KTPQIYIQELIYXXXXXXXXXXXXXXXXQLFKNQINSDFEFFINQNSRSPEYLSLYIDDKLKRGTKGISDQDIDAIFDKCIILFRYLQDKDIFERYYKQHLAKRLLMSKSQSDDQEKSMISKLLIECGGVFTSKLEGMFKDMAISKTLMEEFHSQLQMYTTNTLGIDLFVRVLTTGLWPTQTATQTVCMPDEAQNAFSIY 1617
            S   +KMRI+AFP +M ++ V+ IW+ LK AI EIQ+KNNSGLSFEELYRNAYTMVL K+GE+LY G + VVT+H+I K+R++VL  L NNFL  LN+ W DH TAMVMIRDILMYMDRVYV   +  NVYN G+IIFRD V+R+  IR HLR TLLDM+ RER GEV+ R  +R+ACQML  LG++  ++YEEDFE  FLE S +F++ ES++ L EN++++YI +V   I +E +R    L+ +TE  IV+V+  ELI  H++++V  EN GL HML N K  ++A M+ L  RV NGL TMC C+S +LRE+G+ +V ++   K P  YIQ L+ L+ R +  L  +  N++LFK  I  DFE+F+N NSRSPEYLSL+IDDKLK+G KG+++Q+++ I DK ++LFR++Q+KD+FERYYKQHLA+RLL +KS SDD EK+MISKL  ECG  FTSKLEGMF+DM+IS T M+EF   LQ    +  G+DL VRVLTTG WPTQ+AT    +P   ++AF I+
Sbjct:   10 SRKDTKMRIRAFPMTMDEKYVNSIWDLLKNAIQEIQRKNNSGLSFEELYRNAYTMVLHKHGEKLYTGLREVVTEHLINKVREDVLNSLNNNFLQTLNQAWNDHQTAMVMIRDILMYMDRVYVQQNNVENVYNLGLIIFRDQVVRYGCIRDHLRQTLLDMIARERKGEVVDRGAIRNACQMLMILGLEGRSVYEEDFEAPFLEMSAEFFQMESQKFLAENSASVYIKKVEARINEEIERVMHCLDKSTEEPIVKVVERELISKHMKTIVEMENSGLVHMLKNGKTEDLACMYKLFSRVPNGLKTMCECMSCYLREQGKALVSEEGEGKNPVDYIQGLLDLKSRFDRFLQESFNNDRLFKQTIAGDFEYFLNLNSRSPEYLSLFIDDKLKKGVKGLTEQEVETILDKAMVLFRFMQEKDVFERYYKQHLARRLLTNKSVSDDSEKNMISKLKTECGCQFTSKLEGMFRDMSISNTTMDEFRQHLQATGVSLGGVDLTVRVLTTGYWPTQSATPKCNIPPAPRHAFEIF 535
[Close]
BLAST of Cullin 3 vs. TrEMBL
Match: A0A5J4NTB7 (Cullin 3 OS=Paragonimus westermani OX=34504 GN=DEA37_0001855 PE=3 SV=1)

HSP 1 Score: 677.552 bits (1747), Expect = 0.000e+0
Identity = 339/536 (63.25%), Postives = 424/536 (79.10%), Query Frame = 1 
Query:   19 SGNIRKLDSSVSSNPSKMRIKAFPTSMSDQSVSKIWECLKRAIIEIQKKNNSGLSFEELYRNAYTMVLQKNGEQLYNGTKAVVTDHMIKIRDEVLERLTNNFLAFLNRCWKDHITAMVMIRDILMYMDRVYVTTTDKPNVYNTGMIIFRDTVLRHEAIRRHLRVTLLDMVKRERHGEVISRLQLRDACQMLAQLGVDKLNIYEEDFENYFLEQSRDFYRSESERLLTENASN-LYITQVNKIIEDEAKRARDFLNSTTEAKIVQVLNEELIKNHIESVVNTENFGLTHMLSNKKYSEIALMFNLLKRVDNGLATMCSCISRFLREEGRKIVEDD--KTPQIYIQELIYXXXXXXXXXXXXXXXXQLFKNQINSDFEFFINQNSRSPEYLSLYIDDKLKRGTKGISDQDIDAIFDKCIILFRYLQDKDIFERYYKQHLAKRLLMSKSQSDDQEKSMISKLLIECGGVFTSKLEGMFKDMAISKTLMEEFHSQLQMYTTNTLGIDLFVRVLTTGLWPTQTATQTVCMPDEAQNAFSIY 1617
            SG++R+ D       ++MRIKAF  SM +   ++IWE LK AIIEIQKKNNSGLSFEELYRNAYT+VL K+GE+LY GTKA+V +HMI++RD ++E L N FL++LN CWKDH TAMVMIRDILMYMDRVYV   + P+VY  GM +F + VLR+  IR HL+ TLLDMV+RER GEVISR Q+RDACQM  QLGV  L++Y EDFE  FLEQSR+FYR+ESE  L EN S  LYI +V + IE+E KRA  +L+ +TEAKIV VL ++LI  H+E++V  EN GLTHML++ ++ +IA M+N+L RVD G   M   IS +LRE+GR IV +    TPQ YIQ+L+ LRDRANDLL+ AL N  +F+NQINSDFE+F+N N RSPE+LSL+ID+KLKRGTKG++DQD+DA+FDKCI+LFRYLQ+KD+FE YYK+HLAKRLL+SKSQSDDQEK+MISKL+ ECG V+TSKLEGMFKDMA+SKTLM+EF   L   +  +LG+DL+VRVLTTGLWPTQ+      +P+EA +AF +Y
Sbjct:    4 SGSVRRQDGG----STRMRIKAFANSMDESLANQIWEQLKSAIIEIQKKNNSGLSFEELYRNAYTLVLHKHGERLYAGTKALVCEHMIRVRDSIVENLNNKFLSYLNSCWKDHQTAMVMIRDILMYMDRVYVNQCNLPSVYKMGMTVFCNLVLRYSVIREHLQKTLLDMVRRERRGEVISRSQIRDACQMFVQLGVGSLSVYLEDFELVFLEQSREFYRAESEAFLAENTSAILYIKKVEQRIEEEIKRAHHYLDPSTEAKIVAVLEDQLISRHMETIVGMENSGLTHMLTHDRFEDIAAMYNVLSRVDEGPKIMSHYISMYLREQGRNIVRETGASTPQQYIQDLLQLRDRANDLLVRALNNQTIFRNQINSDFEYFVNLNPRSPEFLSLFIDEKLKRGTKGMADQDVDAVFDKCIVLFRYLQEKDVFEGYYKKHLAKRLLLSKSQSDDQEKNMISKLMAECGAVYTSKLEGMFKDMAVSKTLMDEFSVMLSS-SNRSLGLDLYVRVLTTGLWPTQSIGCGEALPEEAASAFEVY 534
[Close]
BLAST of Cullin 3 vs. TrEMBL
Match: A0A2H1BV54 (Cullin family protein OS=Fasciola hepatica OX=6192 GN=D915_14133 PE=3 SV=1)

HSP 1 Score: 667.922 bits (1722), Expect = 0.000e+0
Identity = 339/536 (63.25%), Postives = 419/536 (78.17%), Query Frame = 1 
Query:   19 SGNIRKLDSSVSSNPSKMRIKAFPTSMSDQSVSKIWECLKRAIIEIQKKNNSGLSFEELYRNAYTMVLQKNGEQLYNGTKAVVTDHMIKIRDEVLERLTNNFLAFLNRCWKDHITAMVMIRDILMYMDRVYVTTTDKPNVYNTGMIIFRDTVLRHEAIRRHLRVTLLDMVKRERHGEVISRLQLRDACQMLAQLGVDKLNIYEEDFENYFLEQSRDFYRSESERLLTENAS-NLYITQVNKIIEDEAKRARDFLNSTTEAKIVQVLNEELIKNHIESVVNTENFGLTHMLSNKKYSEIALMFNLLKRVDNGLATMCSCISRFLREEGRKIVEDDKT--PQIYIQELIYXXXXXXXXXXXXXXXXQLFKNQINSDFEFFINQNSRSPEYLSLYIDDKLKRGTKGISDQDIDAIFDKCIILFRYLQDKDIFERYYKQHLAKRLLMSKSQSDDQEKSMISKLLIECGGVFTSKLEGMFKDMAISKTLMEEFHSQLQMYTTNTLGIDLFVRVLTTGLWPTQTATQTVCMPDEAQNAFSIY 1617
             GN R+ D S     S+MRIK+F   M ++ V++IWE LK AIIEIQKKNNSGLSFEELYR+AYT+VLQK+GE+LY GTKA+V +HMI+IRD ++E L N FL +LN CWKDH TAMVMIRDILMYMDRVYV      +VY  GM +F + VLRH  IR HL+ TLLDMV+RER GEVISR Q+RDACQM  QLG   L +Y EDFE  FLEQSR+FYR+ESE  LTEN S +LYI +V + IE+E KRA  +L+ +TEAKIV VL EEL+  H+E++V  EN GLT++L+  ++ +IA M+N+L R + G   M   IS++LR++GR IV D     PQ YIQ+L  LRDRANDLL+ AL N  +F+NQINSDFE+FIN N+RSPE+LSL+ID+KLKRGTKG++DQD+DA+FDKCI+LFRYLQ+KD+FE YYK+HLAKRLL+SKSQSDDQEK MISKL+ ECG V+TSKLEGMFKDMA+SKTLM+EF++ L   T   LG+DL+VRVLTTGLWPTQ+      +P+EA  AF +Y
Sbjct:    4 GGNARRSDGS----NSRMRIKSFANPMDERLVNQIWEQLKNAIIEIQKKNNSGLSFEELYRSAYTLVLQKHGERLYAGTKALVCEHMIRIRDSIVENLNNKFLTYLNACWKDHQTAMVMIRDILMYMDRVYVGQQKLDSVYKMGMTVFCNLVLRHNVIREHLQKTLLDMVRRERRGEVISRSQIRDACQMFVQLGAGSLRVYLEDFEQPFLEQSREFYRAESENFLTENTSASLYIKKVEQRIEEEIKRAHHYLDPSTEAKIVSVLEEELVSRHMETIVGMENSGLTYLLTQDRFDDIAAMYNVLCRAEEGPKIMSQYISQYLRDQGRNIVRDTGALNPQQYIQDLSQLRDRANDLLVRALNNQTIFRNQINSDFEYFINLNARSPEFLSLFIDEKLKRGTKGMADQDVDAVFDKCIVLFRYLQEKDVFEGYYKKHLAKRLLLSKSQSDDQEKIMISKLMAECGAVYTSKLEGMFKDMAVSKTLMDEFNAMLHS-TNRNLGLDLYVRVLTTGLWPTQSINSCEALPEEAATAFDVY 534
[Close]
BLAST of Cullin 3 vs. TrEMBL
Match: A0A4S2MB97 (CULLIN_2 domain-containing protein OS=Opisthorchis felineus OX=147828 GN=CRM22_002660 PE=3 SV=1)

HSP 1 Score: 662.914 bits (1709), Expect = 0.000e+0
Identity = 329/536 (61.38%), Postives = 421/536 (78.54%), Query Frame = 1 
Query:   19 SGNIRKLDSSVSSNPSKMRIKAFPTSMSDQSVSKIWECLKRAIIEIQKKNNSGLSFEELYRNAYTMVLQKNGEQLYNGTKAVVTDHMIKIRDEVLERLTNNFLAFLNRCWKDHITAMVMIRDILMYMDRVYVTTTDKPNVYNTGMIIFRDTVLRHEAIRRHLRVTLLDMVKRERHGEVISRLQLRDACQMLAQLGVDKLNIYEEDFENYFLEQSRDFYRSESERLLTENASN-LYITQVNKIIEDEAKRARDFLNSTTEAKIVQVLNEELIKNHIESVVNTENFGLTHMLSNKKYSEIALMFNLLKRVDNGLATMCSCISRFLREEGRKIVEDDKTP--QIYIQELIYXXXXXXXXXXXXXXXXQLFKNQINSDFEFFINQNSRSPEYLSLYIDDKLKRGTKGISDQDIDAIFDKCIILFRYLQDKDIFERYYKQHLAKRLLMSKSQSDDQEKSMISKLLIECGGVFTSKLEGMFKDMAISKTLMEEFHSQLQMYTTNTLGIDLFVRVLTTGLWPTQTATQTVCMPDEAQNAFSIY 1617
               +R+ D +V     +MRIKAF  ++ ++  +++WE LK A+IEIQKKN+ GLS+EELYR+AYT+VL K+GE+LY GTK +V++HMI++RD ++E L N FL  LN CW DH T M MIRDILMYMDRVYV   + P+VY  GM +F + VLR+  IR HL+ TLLDMV+RER GEVISR Q+RDACQM  QLGV  L++Y EDFE  FLEQSRDFYR+ESE  L+EN S  LYI +V + IE+E +RA  +L+ +T+ KIV VL EELI  H+E++V  EN GLTHML++ ++ +IA M+N++ RV+ G   M   IS +LRE+GRKIV++  TP  Q YIQ+L+ LRDRANDLL+ AL N  +F+NQINSDFE+FIN N+RSPE+LSL+ID+KLKRGTKG++DQD+DA+FDKCI+LFRYLQ+KD+FE YYK+HLAKRLL+SKSQSDDQEK MISKL+ ECG V+TSKLEGMFKDMA+SKTLM+EF++ L   T   LG+DL+VRVLTTGLWPTQ+    V +P+EA NAF +Y
Sbjct:   17 GSGVRRPDGTVP----RMRIKAFAHTIDERHANQLWEHLKSAMIEIQKKNSGGLSYEELYRSAYTLVLHKHGERLYAGTKDLVSEHMIRVRDSIVENLNNKFLTHLNSCWTDHQTGMAMIRDILMYMDRVYVGQNNLPSVYKMGMTVFCNYVLRYSVIRDHLQKTLLDMVRRERRGEVISRSQIRDACQMFVQLGVGSLSVYLEDFEQPFLEQSRDFYRAESESFLSENTSAILYIKKVEQRIEEEIRRAHHYLDPSTKPKIVAVLEEELISRHMETIVGMENSGLTHMLTHDRFEDIAAMYNVISRVEEGPKIMSHYISMYLREQGRKIVQESGTPSSQQYIQDLLQLRDRANDLLVRALNNQTIFRNQINSDFEYFINLNTRSPEFLSLFIDEKLKRGTKGMADQDVDAVFDKCIVLFRYLQEKDVFEGYYKKHLAKRLLLSKSQSDDQEKIMISKLMAECGAVYTSKLEGMFKDMAVSKTLMDEFNAMLTS-TNRNLGLDLYVRVLTTGLWPTQSVNCCVALPEEAANAFEVY 547
[Close]
BLAST of Cullin 3 vs. TrEMBL
Match: A0A0X3PL62 (Cullin-3 (Fragment) OS=Schistocephalus solidus OX=70667 GN=CUL3 PE=3 SV=1)

HSP 1 Score: 662.144 bits (1707), Expect = 0.000e+0
Identity = 329/539 (61.04%), Postives = 416/539 (77.18%), Query Frame = 1 
Query:   13 IMSGNIRKLDSSVSSNPSKMRIKAFPTSMSDQSVSKIWECLKRAIIEIQKKNNSGLSFEELYRNAYTMVLQKNGEQLYNGTKAVVTDHMIKIRDEVLERLTNNFLAFLNRCWKDHITAMVMIRDILMYMDRVYVTTTDKPNVYNTGMIIFRDTVLRHEAIRRHLRVTLLDMVKRERHGEVISRLQLRDACQMLAQLGVDKLNIYEEDFENYFLEQSRDFYRSESERLLTENAS-NLYITQVNKIIEDEAKRARDFLNSTTEAKIVQVLNEELIKNHIESVVNTENFGLTHMLSNKKYSEIALMFNLLKRVDNGLATMCSCISRFLREEGRKIVEDDKT--PQIYIQELIYXXXXXXXXXXXXXXXXQLFKNQINSDFEFFINQNSRSPEYLSLYIDDKLKRGTKGISDQDIDAIFDKCIILFRYLQDKDIFERYYKQHLAKRLLMSKSQSDDQEKSMISKLLIECGGVFTSKLEGMFKDMAISKTLMEEFHSQLQMYTTNTLGIDLFVRVLTTGLWPTQTATQTVCMPDEAQNAFSIYS 1620
            + +G  R++++S SS   KMRIKAFPTSM ++ +++ WE LKRA++EIQKKNNSGLSFEELYRNAYT+VLQK G+ LY GT+ VV +HM++IR+ V+E L N FL+FLN  WKDH TAM MIRDILMYMDR+YV      NVY  GM  F   VLR+  IR +L+ TLLDMVKRER G+ ISR Q+RDACQM  QLGV  L +YEEDFE  FL Q+R+FYR+ESE  L E+ S  +Y+ +V + IE+E KRA  +L+S+TE K+V VL EELI  H++++VN EN GL  +L++ ++ EIA M+N+L RV  G   M  CIS FLRE G+ IV +  +  PQ YIQ+L+       ++LL +L N Q+F+NQIN+DFE+FIN N +S E+LSL+ID+KL+RGTKG++DQD+DA+FDKC +LFRYLQ+KDIFERYYKQHLAKRLL+SKSQSDDQEKSMISKL+ ECGGVFTSKLEGMFKDMA+SKTLMEEF   LQ  T  T  +DL+VRVLTTGLWPTQ+ +  V +P+EA  AF++YS
Sbjct:    6 MATGGARRVEASSSS---KMRIKAFPTSMDERHINQTWEQLKRAMLEIQKKNNSGLSFEELYRNAYTLVLQKKGDLLYTGTERVVQEHMLRIREAVIEHLNNQFLSFLNTSWKDHQTAMTMIRDILMYMDRIYVPRERLDNVYKMGMTFFCQYVLRYPIIRENLQKTLLDMVKRERLGDAISRPQIRDACQMFVQLGVGSLAVYEEDFEQAFLRQTREFYRAESEAFLAEHTSATMYVQKVEQRIEEEMKRAYQYLDSSTEPKVVAVLEEELISRHLQTIVNMENSGLVFLLTHDRFDEIANMYNVLSRVPEGPKAMSQCISTFLRERGQNIVRESGSSNPQQYIQDLL-QLRDRCNVLLTSLGNKQIFRNQINADFEYFINLNPKSTEFLSLFIDEKLRRGTKGMADQDVDAVFDKCTVLFRYLQEKDIFERYYKQHLAKRLLLSKSQSDDQEKSMISKLMAECGGVFTSKLEGMFKDMAVSKTLMEEF---LQS-TPVTPSLDLYVRVLTTGLWPTQSVSPRVSLPEEAMAAFNVYS 536
[Close]
BLAST of Cullin 3 vs. TrEMBL
Match: A0A183SVC2 (Cullin-3 OS=Schistocephalus solidus OX=70667 GN=SSLN_LOCUS8170 PE=3 SV=1)

HSP 1 Score: 661.759 bits (1706), Expect = 0.000e+0
Identity = 329/539 (61.04%), Postives = 416/539 (77.18%), Query Frame = 1 
Query:   13 IMSGNIRKLDSSVSSNPSKMRIKAFPTSMSDQSVSKIWECLKRAIIEIQKKNNSGLSFEELYRNAYTMVLQKNGEQLYNGTKAVVTDHMIKIRDEVLERLTNNFLAFLNRCWKDHITAMVMIRDILMYMDRVYVTTTDKPNVYNTGMIIFRDTVLRHEAIRRHLRVTLLDMVKRERHGEVISRLQLRDACQMLAQLGVDKLNIYEEDFENYFLEQSRDFYRSESERLLTENAS-NLYITQVNKIIEDEAKRARDFLNSTTEAKIVQVLNEELIKNHIESVVNTENFGLTHMLSNKKYSEIALMFNLLKRVDNGLATMCSCISRFLREEGRKIVEDDKT--PQIYIQELIYXXXXXXXXXXXXXXXXQLFKNQINSDFEFFINQNSRSPEYLSLYIDDKLKRGTKGISDQDIDAIFDKCIILFRYLQDKDIFERYYKQHLAKRLLMSKSQSDDQEKSMISKLLIECGGVFTSKLEGMFKDMAISKTLMEEFHSQLQMYTTNTLGIDLFVRVLTTGLWPTQTATQTVCMPDEAQNAFSIYS 1620
            + +G  R++++S SS   KMRIKAFPTSM ++ +++ WE LKRA++EIQKKNNSGLSFEELYRNAYT+VLQK G+ LY GT+ VV +HM++IR+ V+E L N FL+FLN  WKDH TAM MIRDILMYMDR+YV      NVY  GM  F   VLR+  IR +L+ TLLDMVKRER G+ ISR Q+RDACQM  QLGV  L +YEEDFE  FL Q+R+FYR+ESE  L E+ S  +Y+ +V + IE+E KRA  +L+S+TE K+V VL EELI  H++++VN EN GL  +L++ ++ EIA M+N+L RV  G   M  CIS FLRE G+ IV +  +  PQ YIQ+L+       ++LL +L N Q+F+NQIN+DFE+FIN N +S E+LSL+ID+KL+RGTKG++DQD+DA+FDKC +LFRYLQ+KDIFERYYKQHLAKRLL+SKSQSDDQEKSMISKL+ ECGGVFTSKLEGMFKDMA+SKTLMEEF   LQ  T  T  +DL+VRVLTTGLWPTQ+ +  V +P+EA  AF++YS
Sbjct:    1 MATGGARRVEASSSS---KMRIKAFPTSMDERHINQTWEQLKRAMLEIQKKNNSGLSFEELYRNAYTLVLQKKGDLLYTGTERVVQEHMLRIREAVIEHLNNQFLSFLNTSWKDHQTAMTMIRDILMYMDRIYVPRERLDNVYKMGMTFFCQYVLRYPIIRENLQKTLLDMVKRERLGDAISRPQIRDACQMFVQLGVGSLAVYEEDFEQAFLRQTREFYRAESEAFLAEHTSATMYVQKVEQRIEEEMKRAYQYLDSSTEPKVVAVLEEELISRHLQTIVNMENSGLVFLLTHDRFDEIANMYNVLSRVPEGPKAMSQCISTFLRERGQNIVRESGSSNPQQYIQDLL-QLRDRCNVLLTSLGNKQIFRNQINADFEYFINLNPKSTEFLSLFIDEKLRRGTKGMADQDVDAVFDKCTVLFRYLQEKDIFERYYKQHLAKRLLLSKSQSDDQEKSMISKLMAECGGVFTSKLEGMFKDMAVSKTLMEEF---LQS-TPVTPSLDLYVRVLTTGLWPTQSVSPRVSLPEEAMAAFNVYS 531
[Close]
BLAST of Cullin 3 vs. Ensembl Cavefish
Match: cul3b (cullin 3 [Source:NCBI gene;Acc:103024283])

HSP 1 Score: 594.349 bits (1531), Expect = 0.000e+0
Identity = 292/531 (54.99%), Postives = 389/531 (73.26%), Query Frame = 1 
Query:   37 LDSSVSSNPSKMRIKAFPTSMSDQSVSKIWECLKRAIIEIQKKNNSGLSFEELYRNAYTMVLQKNGEQLYNGTKAVVTDHMI-KIRDEVLERLTNNFLAFLNRCWKDHITAMVMIRDILMYMDRVYVTTTDKPNVYNTGMIIFRDTVLRHEAIRRHLRVTLLDMVKRERHGEVISRLQLRDACQMLAQLGVDKLNIYEEDFENYFLEQSRDFYRSESERLLTENASNLYITQVNKIIEDEAKRARDFLNSTTEAKIVQVLNEELIKNHIESVVNTENFGLTHMLSNKKYSEIALMFNLLKRVDNGLATMCSCISRFLREEGRKIVEDD---KTPQIYIQELIYXXXXXXXXXXXXXXXXQLFKNQINSDFEFFINQNSRSPEYLSLYIDDKLKRGTKGISDQDIDAIFDKCIILFRYLQDKDIFERYYKQHLAKRLLMSKSQSDDQEKSMISKLLIECGGVFTSKLEGMFKDMAISKTLMEEFHSQLQMYTTNTLGIDLFVRVLTTGLWPTQTATQTVCMPDEAQNAFSIY 1617
            L    +   +KMRI+AFP +M ++ V+ IW+ LK AI EIQ+KNNSGLSFEELYRNAYTMVL K+GE+LY G + VVT+H+I K+RD+VL  L NNFL  LN+ W DH TAMVMIRDILMYMDRVYV   +  NVYN G+IIFRD V+R+  IR HL+ TLLDM+ RER GEV+ R  +R+ACQML  LG++  ++YEEDFE  FLE S +F++ ES++ L EN++++YI +V   I +E +R    L+ +TE  IV+V+  ELI  H++++V  EN GL HML N K  ++A M+ L  RV NGL TMC C+S +LRE+G+ +V ++   K P  YIQ L+ L+ R +  L  +  N++LFK  I  DFE+F+N N RSPEYLSL+IDDKLK+G KG+++Q++++I DK ++LFR++Q+KD+FERYYKQHLA+RLL +KS SDD EK+MISKL  ECG  FTSKLEGMF+DM+IS T M+EF   LQ    +  G+DL VRVLTTG WPTQ+AT    +P   ++AF ++
Sbjct:    4 LSKGGTKKDTKMRIRAFPMTMDEKYVNNIWDLLKNAIQEIQRKNNSGLSFEELYRNAYTMVLHKHGEKLYTGLREVVTEHLINKVRDDVLNSLNNNFLQTLNQAWNDHQTAMVMIRDILMYMDRVYVQQNNVENVYNLGLIIFRDQVVRYGCIRDHLQQTLLDMIARERKGEVVDRGAIRNACQMLMILGLEGRSVYEEDFEAPFLEMSAEFFQMESQKFLAENSASVYIKKVEARINEEIERVMHCLDKSTEEPIVKVVERELISKHMKTIVEMENSGLVHMLKNGKTEDLACMYKLFSRVPNGLKTMCECMSSYLREQGKALVSEEGEGKNPVDYIQGLLDLKSRFDRFLQESFNNDRLFKQTIAGDFEYFLNLNPRSPEYLSLFIDDKLKKGVKGLTEQEVESILDKAMVLFRFMQEKDVFERYYKQHLARRLLTNKSVSDDSEKNMISKLKTECGCQFTSKLEGMFRDMSISNTTMDEFRQHLQSTGVSLGGVDLTVRVLTTGYWPTQSATPKCNIPPSPRHAFEVF 534
[Close]
BLAST of Cullin 3 vs. Ensembl Cavefish
Match: cul3a (cullin 3a [Source:ZFIN;Acc:ZDB-GENE-030131-3376])

HSP 1 Score: 594.349 bits (1531), Expect = 0.000e+0
Identity = 294/535 (54.95%), Postives = 391/535 (73.08%), Query Frame = 1 
Query:   25 NIRKLDSSVSSNPSKMRIKAFPTSMSDQSVSKIWECLKRAIIEIQKKNNSGLSFEELYRNAYTMVLQKNGEQLYNGTKAVVTDHMI-KIRDEVLERLTNNFLAFLNRCWKDHITAMVMIRDILMYMDRVYVTTTDKPNVYNTGMIIFRDTVLRHEAIRRHLRVTLLDMVKRERHGEVISRLQLRDACQMLAQLGVDKLNIYEEDFENYFLEQSRDFYRSESERLLTENASNLYITQVNKIIEDEAKRARDFLNSTTEAKIVQVLNEELIKNHIESVVNTENFGLTHMLSNKKYSEIALMFNLLKRVDNGLATMCSCISRFLREEGRKIVEDD---KTPQIYIQELIYXXXXXXXXXXXXXXXXQLFKNQINSDFEFFINQNSRSPEYLSLYIDDKLKRGTKGISDQDIDAIFDKCIILFRYLQDKDIFERYYKQHLAKRLLMSKSQSDDQEKSMISKLLIECGGVFTSKLEGMFKDMAISKTLMEEFHSQLQMYTTNTLGIDLFVRVLTTGLWPTQTATQTVCMPDEAQNAFSIY 1617
            N+  L+   +   +KMRI+AFP +M ++ V+ IW+ LK AI EIQ+KNNSGLSFEELYRNAYTMVL K+GE+LY G + VVT+H+I K+R++VL  L NNFL  LN+ W DH TAMVMIRDILMYMDRVYV   +  NVYN G+IIFRD V+R+  IR HLR TLL+M+ RER GEV+ R  +R+ACQML  LG++  ++YEEDFE  FLE S +F++ ES++ L EN++++YI +V   I +E +R    L+ +TE  IV+V+  ELI  H++++V  EN GL HML N K  ++A M+ L  RV NGL TMC C+S +LRE+G+ +V ++   K P  YIQ L+ L+ R +  L  +  N++LFK  I  DFE+F+N NSRSPEYLSL+IDDKLK+G KG+++Q+++ I DK ++LFR++Q+KD+FERYYKQHLA+RLL +KS SDD EK+MISKL  ECG  FTSKLEGMFKDM+IS T M+EF   LQ    +  G+DL VRVLTTG WPTQ AT    +P   ++AF ++
Sbjct:  119 NMSNLNKPGTKKDTKMRIRAFPMTMDEKYVNNIWDLLKNAIQEIQRKNNSGLSFEELYRNAYTMVLHKHGEKLYTGLREVVTEHLISKVREDVLISLNNNFLQTLNQAWNDHQTAMVMIRDILMYMDRVYVQQNNVENVYNLGLIIFRDQVVRYGCIRDHLRQTLLNMIARERKGEVVDRGAIRNACQMLMILGLEGRSVYEEDFEAPFLEMSAEFFQMESQKFLAENSASVYIKKVEARINEEIERVMHCLDKSTEEPIVKVVERELISKHMKTIVEMENSGLVHMLKNGKTEDLACMYKLFSRVPNGLKTMCECMSLYLREQGKALVSEEGEGKNPVDYIQGLLDLKTRFDRFLQESFSNDRLFKQTIAGDFEYFLNLNSRSPEYLSLFIDDKLKKGVKGLTEQEVEYILDKAMVLFRFMQEKDVFERYYKQHLARRLLTNKSVSDDSEKNMISKLKTECGCQFTSKLEGMFKDMSISNTTMDEFRQHLQSTGVSLGGVDLTVRVLTTGYWPTQAATPKCNIPPSPRHAFEVF 653
[Close]
BLAST of Cullin 3 vs. Ensembl Cavefish
Match: cul4b (cullin 4B [Source:ZFIN;Acc:ZDB-GENE-041008-208])

HSP 1 Score: 268.855 bits (686), Expect = 3.841e-80
Identity = 173/523 (33.08%), Postives = 287/523 (54.88%), Query Frame = 1 
Query:   43 SSVSSNPSKMRIKAFP--TSMSDQSVSKIWECLKRAIIEIQKKNNSGLSFEELYRNAYTMVLQKNGEQLYNGTKAVVTDHMIKIRDEVLERLTNN-FLAFLNRCWKDHITAMVMIRDILMYMDRVYVTTTDK-PNVYNTGMIIFRDTVLRHEAIRRHLRVTLLDMVKRERHGEVISRLQLRDACQMLAQLGVDKLNIYEEDFENYFLEQSRDFYRSESERLLTENASNLYITQVNKIIEDEAKRARDFLNSTTEAKIVQVLNEELIKNHIESVVNTENFGLTHMLSNKKYSEIALMFNLLKRVDNGLATMCSCISRFLREEGRKIVEDDKTPQIYIQELIYXXXXXXXXXXXXXXXXQLFKNQINSDFEFFINQNSRSP-EYLSLYIDDKLKRGTKGISDQDIDAIFDKCIILFRYLQDKDIFERYYKQHLAKRLLMSKSQSDDQEKSMISKLLIECGGVFTSKLEGMFKDMAISKTLMEEFHSQLQMYTTNTLG-IDLFVRVLTTGLWPTQTATQTVCMPDE 1593
            +S      K+ IK F     + +    + W+ LK A+  IQ   +   + EELY+    +   K   +LY   +AV  DH+    D+  E   +  FL  +++CW+DH   M+MIR I +++DR YV      P++++ G+ +FR  ++    ++      +L +++RER GE I R  LR    ML+ L      IY++ FE  FLE++   Y +E +RL+ E     Y+  VNK +E+E++ +   L    E  ++  + ++L+  H+ + +     GL H+L   +  +++L++ L  RV  G+  +      +++  G  IV + +  +  +QEL+  +D+ + ++    + N+ F N +   FE FIN+    P E ++ Y+D KL+ G K  +D++++ + DK +I+FR++  KD+FE +YK+ LAKRLL+ KS S D EKSM+SKL  ECG  FTSKLEGMFKDM +SK +M +F   +Q    N  G I+L V +LT G WPT    + V +P E
Sbjct:  138 NSKPGAAKKLVIKNFKEKPKLPENYTHETWQKLKEAVEAIQNSTSIKYNLEELYQAVENLCSHKISPKLYKQLRAVCEDHIKAQIDQFREYPFHVLFLKKIDKCWQDHCRQMIMIRSIFLFLDRTYVLQNSMLPSIWDMGLELFRFYIISDLKVQSKTIDGILLLIERERSGEAIDRSLLRSLLSMLSDL-----QIYQDSFEQRFLEETNRLYAAEGQRLMQEREVPEYLHHVNKRLEEESRPSHHILGP--EKPLIATVEKQLLGEHLTATLQK---GLNHLLDENRIQDLSLLYQLFSRVRGGVQVLLQHWIEYIKAFGSTIVINPEKDKTMVQELLDFKDKVDSIIDVCFMKNEKFVNAMKEAFETFINKRPNKPAELIAKYVDSKLRAGNKEATDEELEKMLDKIMIIFRFIYGKDVFEAFYKKDLAKRLLVGKSASVDAEKSMLSKLKHECGAAFTSKLEGMFKDMELSKDIMVQFKQYMQ--CQNIPGNIELTVNILTMGYWPTYVPME-VHLPPE 647
[Close]
BLAST of Cullin 3 vs. Ensembl Cavefish
Match: cul4a (cullin 4A [Source:ZFIN;Acc:ZDB-GENE-040426-1357])

HSP 1 Score: 244.202 bits (622), Expect = 7.730e-73
Identity = 141/420 (33.57%), Postives = 241/420 (57.38%), Query Frame = 1 
Query:  373 MIRDILMYMDRVYVTTTDK-PNVYNTGMIIFRDTVLRHEAIRRHLRVTLLDMVKRERHGEVISRLQLRDACQMLAQLGVDKLNIYEEDFENYFLEQSRDFYRSESERLLTENASNLYITQVNKIIEDEAKRARDFLNSTTEAKIVQVLNEELIKNHIESVVNTENFGLTHMLSNKKYSEIALMFNLLKRVDNGLATMCSCISRFLREEGRKIVEDDKTPQIYIQELIYXXXXXXXXXXXXXXXXQLFKNQINSDFEFFINQNSRSP-EYLSLYIDDKLKRGTKGISDQDIDAIFDKCIILFRYLQDKDIFERYYKQHLAKRLLMSKSQSDDQEKSMISKLLIECGGVFTSKLEGMFKDMAISKTLMEEFHSQLQMYTTNTLGIDLFVRVLTTGLWPTQTATQTVCMPDEA---QNAFSIY 1617
            MIR I +++DR YV      P++++TG+ +FR  ++    ++      +L+ ++RER+GE + R  LR    ML+ L      +Y+E FE  FL  +   Y +E +RL+ E     Y+  V + +E+E  R   +L+ +T+  ++  + ++L+  H+ +++     GL+ +L   + +E+ L++ L  +V  GL  +      +++  G +IV   +  +  +QEL+  +D+ +++       N+ F N +   FE FIN+    P E ++ Y+D KL+ G K  ++++++ I DK +I+FR++  KD+FE +YK+ LAKRLL+ KS S D EKSM+SKL  ECG  FTSKLEGMFKDM +SK +M +F   +Q  +  +  I+L V +LT G WPT T  + V +P E    Q  F ++
Sbjct:    1 MIRSIFLFLDRTYVLQNSLLPSIWDTGLELFRTHIVSDNMVQSRTVQGILEQIERERNGETVDRSLLRSLLGMLSDL-----QVYKESFEQKFLVDTDRLYAAEGQRLMLERDVPEYLHHVARRLEEENDRVISYLDQSTQKPLISTVEKQLLGEHMTAILQK---GLSTLLDENRVTELTLLYQLFSKVKGGLPVLLQFWRDYIKSFGGEIVGSPEKDKDMVQELLDFKDKMDNVAQRCFQRNESFINAMKEAFESFINKRPNKPAELIAKYVDSKLRAGNKEATEEELERILDKIMIIFRFIHGKDVFEAFYKKDLAKRLLVGKSASVDAEKSMLSKLKHECGAAFTSKLEGMFKDMELSKDIMIQFKQYMQNQSEPS-NIELTVNILTMGYWPTYTPME-VHLPAEMVKLQEVFKMF 410
[Close]
BLAST of Cullin 3 vs. Ensembl Cavefish
Match: ENSAMXT00000057183.1 (pep primary_assembly:Astyanax_mexicanus-2.0:APWO02001049.1:257741:270576:1 gene:ENSAMXG00000034138.1 transcript:ENSAMXT00000057183.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 221.09 bits (562), Expect = 4.741e-64
Identity = 145/417 (34.77%), Postives = 233/417 (55.88%), Query Frame = 1 
Query:  370 VMIRDILMYMDRVYVTTTDKPNVYNT------GMIIFRDTVLRHEAIRRHLRVTLLDMVKRERHGEVISRLQLRDACQMLAQLGVDKLNIYEEDFENYFLEQSRDFYRSESERLLTENASNLYITQVNKIIEDEAKRARDFLNSTTEAKIVQVLNEELIKNHIESVVNTENFGLTHMLSNKKYSEIALMFNLLKRVDNGLATMCSCISRFLREEGRKIVEDDKTPQIYIQELIYXXXXXXXXXXXXXXXXQLFKNQINSDFEFFINQNSRSPEYL--SLYIDDKLKRGTKGISDQDIDAIFDKCIILFRYLQDKDIFERYYKQHLAKRLLMSKSQSDDQEKSMISKLLIECGGVFTSKLEGMFKDMAISKTLMEEFHSQLQMYTTNTLG-IDLFVRVLTTGLWPTQTATQTVCMPDE 1593
            +MIR I     R YV T    ++  T      G+ +FR  ++    ++      +L +++RER GE I R  LR    ML+ L      IY++ FE  FLE++   Y +E +RL+ E     Y+  VNK +E+EA R   +L+ +T+  ++  + ++L+  H+ + +     GL H+L   +  +++L++ L  RV  G+  +      +++  G  IV + +  +  +QEL+  +D+ + ++    + N+ F N +   FE FIN+    P  L  S Y+D KL+ G K  +D++++ + DK +I+FR++  KD+FE +YK+ LAKRLL+ KS S D EKSM+SKL  ECG  FTSKLEGMFKDM +SK +M +F   +Q    N  G I+L V +LT G WPT    + V +P E
Sbjct:   17 IMIRSIFFVFGRTYVLTNLCCHLSGTYLLLDMGLELFRFYIISDLKVQSKTIDGILLLIERERSGEAIDRSLLRSLLSMLSDL-----QIYQDSFEQRFLEETNRLYAAEGQRLMQEREVPEYLHHVNKRLEEEADRVITYLDQSTQKPLIATVEKQLLGEHLTATLQK---GLNHLLDENRIQDLSLLYQLFSRVRGGVQVLLQHWIEYIKAFGSTIVINPEKDKTMVQELLDFKDKVDSIIDVCFMKNEKFVNAMKEAFETFINKRPNKPAELIGSKYVDSKLRAGNKEATDEELEKMLDKIMIIFRFIYGKDVFEAFYKKDLAKRLLVGKSASVDAEKSMLSKLKHECGAAFTSKLEGMFKDMELSKDIMVQFKQYMQ--CQNIPGNIELTVNILTMGYWPTYVPME-VHLPPE 422
[Close]
BLAST of Cullin 3 vs. Ensembl Sea Lamprey
Match: cul4b (cullin 4B [Source:ZFIN;Acc:ZDB-GENE-041008-208])

HSP 1 Score: 270.396 bits (690), Expect = 1.811e-83
Identity = 171/529 (32.33%), Postives = 292/529 (55.20%), Query Frame = 1 
Query:   43 SSVSSNPS---KMRIKAF--PTSMSDQSVSKIWECLKRAIIEIQKKNNSGLSFEELYRNAYTMVLQKNGEQLYNGTKAVVTDHMIKIRDEVLERLTNN-----FLAFLNRCWKDHITAMVMIRDILMYMDRVYVTTTDK-PNVYNTGMIIFRDTVLRHEAIRRHLRVTLLDMVKRERHGEVISRLQLRDACQMLAQLGVDKLNIYEEDFENYFLEQSRDFYRSESERLLTENASNLYITQVNKIIEDEAKRARDFLNSTTEAKIVQVLNEELIKNHIESVVNTENFGLTHMLSNKKYSEIALMFNLLKRVDNGLATMCSCISRFLREEGRKIVEDDKTPQIYIQELIYXXXXXXXXXXXXXXXXQLFKNQINSDFEFFINQNSRSP-EYLSLYIDDKLKRGTKGISDQDIDAIFDKCIILFRYLQDKDIFERYYKQHLAKRLLMSKSQSDDQEKSMISKLLIECGGVFTSKLEGMFKDMAISKTLMEEFHSQLQMYTTNTLGIDLFVRVLTTGLWPTQTATQTVCMPDE 1593
            SS ++ P    K+ IK F     + D   ++ W+ L+ A+  IQ   +   + EELY+    +   K   +LY   + V  +H   IR ++      +     FL  +++CW+DH   M+MIR I +++DR YV      P++++ G+ +FR  V+    ++      LL +++RER GE + R  LR    ML+      L IY++ FE  FL ++   Y +E +RL+ E     Y+  VNK +E+E+ R   +L+ +T+  ++  + ++L+  H+ +++     G  ++L   +  E++L++ L  RV  G+  +    + +++  G  IV + +  +  +QEL+  +++ + ++      +  F N +   FE FIN+    P E ++ Y+D KL+ G K  +D++++ + DK +I+FR++  KD+FE +YK+ LAKRLL+ KS S D EKSM+SKL  ECGG FTSKLEGMFKDM +SK +M +F   +Q    +   I+L V +LT G WPT T  + V +P E
Sbjct:   28 SSGNNKPGSAKKLVIKNFRDKPKLPDSYPAETWQKLQEAVQAIQNSTSIKYNLEELYQAVENLCSYKISAKLYLQLRQVCEEH---IRAQIQHFWAGSMDSVLFLKHIDKCWQDHCRQMIMIRSIFLFLDRTYVLQNSMLPSIWDMGLELFRTHVVSDRLVQNRTIDGLLLLIERERSGETVDRSLLRSLLSMLS-----DLQIYQDCFEQRFLVETNRLYAAEGQRLMQEREVPEYLHHVNKRLEEESDRIITYLDQSTQKSLIATVEKQLLGEHLTAILQK---GAANLLDENRIPELSLLYQLFSRVKGGIQVLLQHWADYIKVFGTTIVVNPEKDKTMVQELLDFKEKVDVIVEVCFQRSDKFINAMKEAFETFINKRLNKPAELIAKYVDSKLRAGNKEATDEELERLLDKIMIIFRFIHGKDVFEAFYKKDLAKRLLVGKSASVDAEKSMLSKLKHECGGAFTSKLEGMFKDMELSKDIMIQFKQYMQ-NQNDANNIELTVNILTMGYWPTYTPME-VHLPPE 543
[Close]
BLAST of Cullin 3 vs. Ensembl Sea Lamprey
Match: cul1b (cullin 1b [Source:ZFIN;Acc:ZDB-GENE-040426-2887])

HSP 1 Score: 193.356 bits (490), Expect = 8.180e-54
Identity = 144/560 (25.71%), Postives = 282/560 (50.36%), Query Frame = 1 
Query:   88 PTSMSDQSVSKIWECLKRAIIEIQKKNNSGLS-FEELYRNAY---TMVLQKN-------------------------GEQLYNGTKAVVTDHMIKIRDEVLERLTNNFLAFLNRCWKDHITAMVMIRDILMYMDRVYVT-TTDKP-----NVYNTGMIIFRDTVLRHEAIRRHLRVTLLDMVKRERHGEVISRLQLRDACQMLAQLGVDK---------LNIYEEDFENYFLEQSRDFYRSESERLLTENASNLYITQVNKIIEDEAKRARDFLNSTTEAKIVQVLNEELIKNHIESVVNTENFGLTHMLSNKKYSEIALMFNLLKRVDNGLATMCSCISRFLREEGRKIVEDD-----KTPQIYIQELIYXXXXXXXXXXXXXXXXQLFKNQINSDFEFFINQN---------SRSPEYLSLYIDDKLKRGTKGISDQDIDAIFDKCIILFRYLQDKDIFERYYKQHLAKRLLMSKSQSDDQEKSMISKLLIECGGVFTSKLEGMFKDMAISKTLMEEFHSQLQMYTTNTLGIDLFVRVLTTGLWPTQTATQTVCMPDE 1593
            P  +    + +IW+ LK  I ++  + +   S + ELY + Y   T V Q N                         G +LY   K  +  +++ +  +  + +    L F  + W+D+  +  ++  I  Y++R +V    D+       +Y+  ++ +R+ + +   + + +   +L ++++ER GE I+   +        +LG+++         L++Y+E FE+ FL  +  FY  ES   L++N    Y+ +    + +E +R + +L+ +T  ++ +   + LI+ H+E+  +       ++L + K  ++A M++L+ R+ +GL  + S +   +  +G   +E         P+IY+Q ++ +  + N L+++A  N+  F   ++     FIN N         S+SPE L+ Y D  LK+ +K   + +++   ++ +++F+Y++DKD+F+R+Y + LAKRL+   S SDD E SMISKL   CG  +TSKL+ MF+D+ +SK L E+F + L    +  L +D  ++VL++G WP Q +  T  +P E
Sbjct:    7 PHGLKQIGLDQIWDDLKAGIQQVYTRQSMAKSRYMELYTHVYNYCTSVHQANQARSGAMANTSKNKKGQPSGGAQFVGLELYKRLKDFLKMYLLNLLKDGEDLMDEGVLKFYTQQWEDYRFSSKVLNGICSYLNRHWVRRECDEGRKGIYEIYSLALVTWRECLFK--PLNKQVTNAVLKLIEKERTGETINTRLISGVVGSYVELGLNEDDLHAKGPTLSVYKEAFESQFLLDTERFYTRESTDFLSQNPVTEYMKKAETRLLEEQRRVQVYLHESTHDELARKCEQVLIEKHLENFYSE----FQNLLDDDKNEDLARMYSLVSRILDGLGELKSLLETHIHNQGLSAIEKCGEGALNDPKIYVQTILDVHKKYNALVMSAFNNDAGFVASLDKACGRFINTNAVTKMAQTSSKSPELLARYCDSLLKKSSKNPEEAELEDTLNQVMVVFKYIEDKDVFQRFYAKMLAKRLVNHNSASDDAEASMISKLKQACGFEYTSKLQRMFQDIGVSKDLNEQFKNHLA--NSEPLDLDFSIQVLSSGSWPFQQSC-TFALPSE 557
[Close]
BLAST of Cullin 3 vs. Ensembl Sea Lamprey
Match: cul1b (cullin 1b [Source:ZFIN;Acc:ZDB-GENE-040426-2887])

HSP 1 Score: 190.66 bits (483), Expect = 4.817e-53
Identity = 145/535 (27.10%), Postives = 278/535 (51.96%), Query Frame = 1 
Query:  109 SVSKIWECLKRAIIEIQKKNNSGLS-FEELYRNAY---TMVLQKN---------GEQLYNGTKAVVTDHMIKIRDEVLERLTNNFLAFLNRC---WKDHITAMVMIRDILMYMDRVYVT-TTDKP-----NVYNTGMIIFRDTVLRHEAIRRHLRVTLLDMVKRERHGEVISRLQLRDACQMLAQLGVDKLNIYEEDFENYFLEQSRDFYRSESERLLTENASNLYITQVNKIIEDEAKRARDFLNSTTEAKIVQVLNEELIKNHIESVVNTENFGLTHMLSNKKYSEIALMFNLLKRVDNGLATMCSCISRFLREEGRKIVEDD-----KTPQIYIQELIYXXXXXXXXXXXXXXXXQLFKNQINSDFEFFINQN---------SRSPEYLSLYIDDKLKRGTKGISDQDIDAIFDKCIILFRYLQDKDIFERYYKQHLAKRLLMSKSQSDDQEKSMISKLLIECGGVFTSKLEGMFKDMAISKTLMEEFHSQLQMYTTNTLGIDLFVRVLTTGLWPTQTATQTVCMPDEAQNA 1605
             + +IW+ LK  I ++  + +   S + ELY + Y   T V Q N         G +LY   K  +  +++ +  +V   L    L+  ++C   W+D+  +  ++  I  Y++R +V    D+       +Y+  ++ +R+ + +   + + +   +L ++++ER GE I+   +       A L V     Y+E FE+ FL  +  FY  ES   L++N    Y+ +    + +E +R + +L+ +T  ++ +   + LI+ H+E+  +       ++L + K  ++A M++L+ R+ +GL  + S +   +  +G   +E         P+IY+Q ++ +  + N L+++A  N+  F   ++     FIN N         S+SPE L+ Y D  LK+ +K   + +++   ++ +++F+Y++DKD+F+R+Y + LAKRL+   S SDD E SMISKL   CG  +TSKL+ MF+D+ +SK L E+F + L    +  L +D  ++VL++G WP Q +  T  +P E + +
Sbjct:    2 GLDQIWDDLKAGIQQVYTRQSMAKSRYMELYTHVYNYCTSVHQANQPSGGAQFVGLELYKRLKDFLKMYLLNLLKKVPAALFRPRLS--HKCTVQWEDYRFSSKVLNGICSYLNRHWVRRECDEGRKGIYEIYSLALVTWRECLFK--PLNKQVTNAVLKLIEKERTGETINTRLISGVVGSYATLSV-----YKEAFESQFLLDTERFYTRESTDFLSQNPVTEYMKKAETRLLEEQRRVQVYLHESTHDELARKCEQVLIEKHLENFYSE----FQNLLDDDKNEDLARMYSLVSRILDGLGELKSLLETHIHNQGLSAIEKCGEGALNDPKIYVQTILDVHKKYNALVMSAFNNDAGFVASLDKACGRFINTNAVTKMAQTSSKSPELLARYCDSLLKKSSKNPEEAELEDTLNQVMVVFKYIEDKDVFQRFYAKMLAKRLVNHNSASDDAEASMISKLKQACGFEYTSKLQRMFQDIGVSKDLNEQFKNHLA--NSEPLDLDFSIQVLSSGSWPFQQSC-TFALPSELERS 520
[Close]
BLAST of Cullin 3 vs. Ensembl Sea Lamprey
Match: cul2 (cullin 2 [Source:ZFIN;Acc:ZDB-GENE-030131-8032])

HSP 1 Score: 150.214 bits (378), Expect = 6.550e-39
Identity = 104/392 (26.53%), Postives = 203/392 (51.79%), Query Frame = 1 
Query:  484 EAIRRHLRVTLLDMVKRERHGEVISRLQLRDACQMLAQLGVDK----LNIYEEDFENYFLEQSRDFYRSESERLLTENASNLYITQVNKIIEDEAKRARDFLNSTTEAKIVQVLNEELIKNHIESVVNTENFGLTHMLSNKKYSEIALMFNLLKRVDNGLATMCSCISRFLREEGRKIVED---DKTPQIYIQELIYXXXXXXXXXXXXXXXXQLFKNQINSDFEFFINQN-----SRSPEYLSLYIDDKLKRGTKGISDQDIDAIFDKCIILFRYLQDKDIFERYYKQHLAKRLLMSKSQSDDQEKSMISKLLIECGGVFTSKLEGMFKDMAISKTLMEEFHSQLQMYTTNT-LGIDLFVRVLTTGLWP-TQTATQTVCMPDEAQNAFSIY 1617
            E +   L   LL  +K +R GE  ++  +         +   K    L  Y++ FE+ FL ++ ++++ E+ RLL     + Y+ QV   ++DE  R R +L+ ++ +K++    + ++ +H++  +++E      ++  +   ++A M+ LL+ V   L  M +     +R+EG K + +   +  P  +++ ++ +  +   L+ + L  +Q F + ++      +N        +SPE L+ Y D  LK+  KG+++ ++D      I++F+Y+ DKD+F+++Y + LAKRL+   S S D E+SMI+KL   CG  FTSKL  M+ DM++S  L  +F + ++   T   LG+   + VL  G WP +Q  +    +P E +    ++
Sbjct:  151 EPLEGSLVRVLLKEIKNDRSGENPNQKVIHGVINSFVHVEQYKKKFPLKFYQDVFESAFLVETGEYFKQEASRLLQTCNCSQYMQQVLGRLKDEEVRCRKYLHPSSYSKVISECQQRMVADHLQ-FLHSE---CQTIVRQELRDDMANMYTLLRTVPQALQHMVTEQQEHIRQEGLKAISNLSHENMPTQFVESVLEVHSKYVQLITSVLSGDQQFMSALDKACSAVVNYREPKSLCKSPELLAKYCDGMLKKTAKGMTENEVDDKLSNSIVVFKYIDDKDVFQKFYARMLAKRLIHGLSMSMDSEESMINKLKQACGYEFTSKLHRMYTDMSLSADLNNKFGNFIKEQETPIDLGVGFQIYVLQAGAWPLSQLPSTPFVIPQELEKCVRMF 538
[Close]
BLAST of Cullin 3 vs. Ensembl Sea Lamprey
Match: cul5a (cullin 5a [Source:ZFIN;Acc:ZDB-GENE-030131-5426])

HSP 1 Score: 60.8474 bits (146), Expect = 3.099e-10
Identity = 40/160 (25.00%), Postives = 78/160 (48.75%), Query Frame = 1 
Query:  490 IRRHLRVTLLDMVKRERHGEVISR---LQLRDACQMLAQLGVDKLNIYEEDFENYFLEQSRDFYRSESERLLTENASNLYITQVNKIIEDEAKRARDFLNSTTEAKIVQVLNEELIKNHIESVVNTENFGLTHMLSNKKYSEIALMFNLLKRVDNGLATM 960
            I+  L+ + + +V  ER GE       + +R++   L     D+L IY E+FE  +L+ +  FYR+++   L +N    ++   +  +++E +RA  +L +  +   VQ L +  +   + S   T     + M+   +  ++ LMF L+ RV  G+  M
Sbjct:  154 IKGRLQDSAMKLVHSERLGEAFDSQLVIGVRESYVNLCSNAEDRLQIYRENFEKAYLDATDTFYRTQAPAYLQQNGVQNFMKYADAKLKEEEQRALRYLETRKDCNSVQALVDCCVNALVTSFKETILAECSGMIKANETEKLQLMFQLMDRVPAGIEPM 313
[Close]
BLAST of Cullin 3 vs. Ensembl Yeast
Match: CDC53 (Cullin; structural protein of SCF complexes (which also contain Skp1p, Cdc34p, Hrt1p and an F-box protein) involved in ubiquitination; SCF promotes the G1-S transition by targeting G1 cyclins and the Cln-CDK inhibitor Sic1p for degradation; human homolog CUL1 can complement yeast cdc53 null mutant [Source:SGD;Acc:S000002290])

HSP 1 Score: 118.242 bits (295), Expect = 1.696e-28
Identity = 125/544 (22.98%), Postives = 238/544 (43.75%), Query Frame = 1 
Query:  184 FEELYRNAYTMVLQKNGEQLYNGTKAVVTDHMIKIRDEVLERLTN---------------NFLAFLNRCWKDHITAMVMIRDILMYMDRVYVT---TTDKPNVYNTG---MIIFRDTVLRHEAIRRHLRVTLLDMVKRERHGEVISRLQLRDACQMLAQLGVDK-------LNIYEEDFENYFLEQSRDFYRSESERLLTENASNLYITQVNKIIEDEAKRARDFLNSTTEAKIVQVLNEELIKNHIESVVNTENFGLTHMLSNKKYSEIALMFNLLKRVDNGLATMCSCISRFLREEG------------RKIVEDDK--------------TPQIYIQELIYXXXXXXXXXXXXXXXXQLFKNQINSDFEFFINQN-------------SRSPEYLSLYIDDKLKRGTKG-----ISDQDIDAIFDKCIILFRYLQDKDIFERYYKQHLAKRLLMSKSQSDDQEKSMISKLLIECGGVFTSKLEGMFKDMAISKTLMEEFHSQLQMYTTNTLG--IDLFVRVLTTGLWPTQTATQTVCMPDE 1593
            + E+Y   Y   + K+    +  T +      I +  E+ E+L N                FL F  + WK      + +     YM+R +V    +  K ++++     ++ +++ +   +  +  L   LLD V   R G++I R  +  A + L  LG+D        LN+Y + FE  FL++++++Y   +   L +++   YI + ++II+ E K    + +  T+  +   LN+ LI +HIE + N        +L  +   +I  ++ L++R    +  M S    ++++ G              I++++               +P+ YI++L+ + D  + +   +  ++      +++    FIN N             S++ E L+ Y D  LK+ TK      +SD+DI       I +F+YL DKD FE +Y++  AKRL+   S S + E+++I +L       +T K+  MF+D+ +SK L ++F   L+     +     DL   VL   +WP         +P E
Sbjct:   48 YMEVYTAIYNYCVNKSRSSGHFSTDSRTGQSTILVGSEIYEKLKNYLKNYILNFKQSNSETFLQFYVKRWKRFTIGAIFLNHAFDYMNRYWVQKERSDGKRHIFDVNTLCLMTWKEVMF--DPSKDVLINELLDQVTLGREGQIIQRSNISTAIKSLVALGIDPQDLKKLNLNVYIQVFEKPFLKKTQEYYTQYTNDYLEKHSVTEYIFEAHEIIKREEKAMTIYWDDHTKKPLSMALNKVLITDHIEKLENE----FVVLLDARDIEKITSLYALIRRDFTLIPRMASVFENYVKKTGENEISSLLAMHKHNIMKNENANPKKLALMTAHSLSPKDYIKKLLEVHDIFSKIFNESFPDDIPLAKALDNACGAFININEFALPAGSPKSATSKTSEMLAKYSDILLKKATKPEVASDMSDEDI-------ITIFKYLTDKDAFETHYRRLFAKRLIHGTSTSAEDEENIIQRLQAANSMEYTGKITKMFQDIRLSKILEDDFAVALKNEPDYSKAKYPDLQPFVLAENMWPFSYQEVEFKLPKE 578
[Close]
BLAST of Cullin 3 vs. Ensembl Yeast
Match: CUL3 (Ubiquitin-protein ligase; forms a complex with Elc1p that polyubiquitylates monoubiquitylated RNA polymerase II to trigger its proteolysis; cullin family member with similarity to Cdc53p and human CUL3 [Source:SGD;Acc:S000003235])

HSP 1 Score: 102.449 bits (254), Expect = 2.551e-23
Identity = 131/508 (25.79%), Postives = 230/508 (45.28%), Query Frame = 1 
Query:  133 LKRAIIEIQKKNNSGLSFEELYRNAYTMVLQKNGEQLYNGTKAVVTDHMIKIRDEVLERLTNN--FLAFLNRCWKDHITAMVMIRDILMYMDRVYVTTTDKPN----VYNTGMIIFRDTVLRHEAIRRHLRVTLLDMVKRERHGEVISRLQ--LRDACQMLAQLGVDKLNIYEEDFENYFLEQSRDFYRSESE-RLLTENASNLYITQVNKIIEDEAKRARDFLNSTTEAKIVQVLNEELIKNHIESVVNTENFGLTH---MLSNKKY--------SEIALMFNLLKRVDNGLATMCSCISRFLREEGRK-----IVEDDKTPQIYIQELIYXXXXXXXXXXXXXXXXQLFKNQINSDFEFFINQNSRSP-EYLSLYIDDKLKRGTKGISDQDIDAIFDKCI---ILFRYLQDKDIFERYYKQHLAKRLLMSKSQSDDQEKSMISKLLIECGGVFTSKLEGMFKDMAISKTLMEEFHSQLQMYTTNTLGIDLFV-RVLTTGLWPTQTA 1566
            +K AI  I   + + LSFE++Y+  YT+VL K G  LYN  K  +   +  +R+ +++  T++  FL  + R W+       +  D++MYMD+VY     KPN    VY+  + +FR  +L+ +     +   + D+ +    G V S      +    M+  L  ++ + +  DFE   +  + ++Y    +  LLT   S   + ++ K+ + E+     FLN  +  K+  VL   LI   +  ++      LTH   ++SN K         SE      +++ + + +    + I+    E  RK     I    +  ++Y  +  +L       +    L   +    +   F  + ++    P EYLS Y+D  +KR  +   D +I  I    +    L   L +KDIFE+ YK+ L++RLL  +S   + EK M+  +    G  FTSKLE M +D+++S  + + F    Q  T N++    F  +VLT   WP Q+ 
Sbjct:   29 VKYAIDHIYSDDMADLSFEQVYKTIYTIVLNKKGPILYNRLKDYLIQKLALLRETIVKDNTHDYEFLGTMARLWEVQCHCFKITGDLMMYMDKVYC----KPNRCMEVYDMCLDLFRIEILQ-KCSSSLISALISDIERIRNLGSVDSEHTSLWKVLIGMMETLHDNRDSFFLTDFEPVLISATEEYYNKAIDIELLTPIES---LEKIRKLRQFESMLDSSFLNVDSHNKLKTVLENVLIWGKLSDIIE----DLTHEAMVISNGKLLQEIYDLSSEEKYRVTVIESIKSYINK--NAINIPFNEGNRKKGQNAITWSSEIVELYRSQHSFLESIDFGSVRLNNLTGDVSNAILGDVFSMYFSKEGALPSEYLSTYVDHCMKRTKE--KDAEIVKIKQDLLDSTKLIGLLTEKDIFEKIYKKQLSRRLLQQRSLV-EIEKWMVQMIKKVLGTFFTSKLEIMLRDISLSSEMYQAF----QHSTINSIEYLSFAPQVLTRTSWPFQST 515
[Close]
BLAST of Cullin 3 vs. Ensembl Nematostella
Match: EDO35230 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SM65])

HSP 1 Score: 498.049 bits (1281), Expect = 2.591e-170
Identity = 251/474 (52.95%), Postives = 344/474 (72.57%), Query Frame = 1 
Query:  214 MVLQKNGEQLYNGTKAVVTDHM-IKIRDEVLERLTNNFLAFLNRCWKDHITAMVMIRDILMYMDRVYVTTTDKPNVYNTGMIIFRDTVLRHEAIRRHLRVTLLDMVKRERHGEVISRLQLRDACQMLAQLGVDKLNIYEEDFENYFLEQSRDFYRSESERLLTENASNLYITQVNKIIEDEAKRARDFLNSTTEAKIVQVLNEELIKNHIESVVNTENFGLTHMLSNKKYSEIALMFNLLKRVDNGLATMCSCISRFLREEGRKIVEDDKT-----PQIYIQELIYXXXXXXXXXXXXXXXXQLFKNQINSDFEFFINQNSRSPEYLSLYIDDKLKRGTKGISDQDIDAIFDKCIILFRYLQDKDIFERYYKQHLAKRLLMSKSQSDDQEKSMISKLLIECGGVFTSKLEGMFKDMAISKTLMEEFHSQLQMYTTNTLGIDLFVRVLTTGLWPTQTATQTVCMPDEAQNAFSIY 1617
            MVL K+GE+LYNG K VVT+H+  KIR +V+  L NNFL  LN  W DH T+MVMIRDILMYMDRVYV      NVYN G+I+FRD V+R+  IR HL  TLL +V++ER GEV+ R+ +R+ACQML  LG+D  ++YEEDFE  FLE+S +FY+ E ++ L EN++++YI +V   I +E++RA+ +L+ +TE  +V+V+ EELI+ H++++V+ EN G+ HML + K  ++A M+ L  RV  GL T+C C+  +LRE+G+ +V D+++     P   IQ L+ L+DR +  L N   +++LFK  I S+FE+F+N N +SPE+LSL+IDDKLK+G KG S+Q+++ + DKC++LFR+LQ+KD+FERYYKQHLAKRLL+ KS SDD EK+MISKL  ECG  FTSKLEGMFKDM +S T  EEF   L     N LG+DL VRVLTTG WPTQ+      +P +AQ+AF  +
Sbjct:    1 MVLHKHGERLYNGLKQVVTEHLEDKIRKDVVASLNNNFLDTLNAAWNDHQTSMVMIRDILMYMDRVYVQQNGVDNVYNLGLILFRDKVVRYGNIRDHLCQTLLSLVRKERRGEVVDRMAIRNACQMLVILGIDSRHVYEEDFERPFLEESAEFYKMEGQKFLAENSASIYIQKVETRINEESERAKHYLDPSTEESVVKVVEEELIRKHMKTIVDMENSGVIHMLKHDKIEDLARMYRLFYRVKEGLKTVCDCMRGYLREQGKAVVVDEESETARNPISCIQNLLELKDRFDHFLHNGFSSDRLFKQAIGSEFEYFLNLNGKSPEFLSLFIDDKLKKGVKGYSEQEVEVVLDKCMVLFRFLQEKDVFERYYKQHLAKRLLLQKSVSDDSEKNMISKLKTECGCQFTSKLEGMFKDMTVSHTTNEEFRQHLSNSQINLLGVDLIVRVLTTGFWPTQSGNHKCNVPPQAQHAFDCF 474
[Close]
BLAST of Cullin 3 vs. Ensembl Nematostella
Match: EDO35660 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SKY8])

HSP 1 Score: 227.639 bits (579), Expect = 1.837e-67
Identity = 120/349 (34.38%), Postives = 213/349 (61.03%), Query Frame = 1 
Query:  514 LLDMVKRERHGEVISRLQLRDACQMLAQLGVDKLNIYEEDFENYFLEQSRDFYRSESERLLTENASNLYITQVNKIIEDEAKRARDFLNSTTEAKIVQVLNEELIKNHIESVVNTENFGLTHMLSNKKYSEIALMFNLLKRVDNGLATMCSCISRFLREEGRKIVEDDKTPQIYIQELIYXXXXXXXXXXXXXXXXQLFKNQINSDFEFFINQNSRSP-EYLSLYIDDKLKRGTKGISDQDIDAIFDKCIILFRYLQDKDIFERYYKQHLAKRLLMSKSQSDDQEKSMISKLLIECGGVFTSKLEGMFKDMAISKTLMEEFHSQLQMYTTNTLGIDLFVRVLTTGLWPT 1557
            LL M+++ERHGE + R  L+   +MLA +      +YE+ FE+ FLE +   Y  E  R + E     Y+  V+K +++E  R   +L+ +T   ++  + ++L+  H+ S++     G  +++ + + +++ALM+ L  RV  G+  +C+  S F++++G  IV + +  +  +QEL+  +++ + ++  A + ++ F N +   FE FIN+    P E ++ ++D KL+ G K  ++++++ + D+ +++FR++  KD++E +YK+ LAKRLL+ KS S D EKSM+SKL  ECG  FTSKLEGMFKDM +SK +M +F   LQ + +    +D+ V +LT G WPT
Sbjct:   14 LLQMIEKERHGEAVDRSLLKSLLRMLADI-----QMYEDAFESKFLEATDVLYSQEGNRYMQETDVPKYLAHVDKRLKEEMDRLIHYLDQSTRKPLILCVEKQLLGQHLTSILQK---GFDNLMLSNRIADLALMYQLFGRVRKGMEELCAAFSGFIKKQGISIVLNPEKDKTMVQELLDFKEQLDTMIAEAFMKSEKFVNAMKESFESFINKRPNKPAELIAKFVDSKLRAGNKEATEEELERLLDRIMVIFRFIHGKDVYEAFYKKDLAKRLLVGKSASVDAEKSMLSKLKQECGAAFTSKLEGMFKDMELSKDVMVQFRQYLQ-HQSLPWNMDMVVSILTMGYWPT 353
[Close]
BLAST of Cullin 3 vs. Ensembl Nematostella
Match: EDO37570 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SFF7])

HSP 1 Score: 198.364 bits (503), Expect = 2.833e-55
Identity = 144/562 (25.62%), Postives = 286/562 (50.89%), Query Frame = 1 
Query:   82 AFPTSMSDQSVSKIWECLKRAIIEI-QKKNNSGLSFEELYRNAY---TMVLQKN-------------------GEQLYNGTKAVVTDHMIKIRDEVLERLTNNFLAFLNRCWKDHITAMVMIRDILMYMDRVYVT-TTDKP-----NVYNTGMIIFRDTVLRHEAIRRHLRVTLLDMVKRERHGEVISRLQLRDACQMLAQLGVDK---------LNIYEEDFENYFLEQSRDFYRSESERLLTENASNLYITQVNKIIEDEAKRARDFLNSTTEAKIVQVLNEELIKNHIESVVNTENFGLTHMLSNKKYSEIALMFNLLKRVDNGLATMCSCISRFLREEGRKIVE-------DDKTPQIYIQELIYXXXXXXXXXXXXXXXXQLFKNQINSDFEFFINQN---------SRSPEYLSLYIDDKLKRGTKGISDQDIDAIFDKCIILFRYLQDKDIFERYYKQHLAKRLLMSKSQSDDQEKSMISKLLIECGGVFTSKLEGMFKDMAISKTLMEEFHSQLQMYTTNTLGIDLFVRVLTTGLWPTQTATQTVCMPDEAQNA 1605
            A P  +   ++ +IW+ LK  I  +  +++ S   + ELY + Y   T V Q++                   G +LY   K  +  +++ ++ +  + +  + L F +  W+D+  +  ++  +  Y++R +V    D+       +Y   ++ +R+ + R   + + +   +L +++RER+GE I+   +    Q   +LG+++         L +Y++ FE+ FLE +  FY +ES   L EN    Y+ +    + +E +R   +L+ +T+ ++ +   + LI+ H++ +   E     ++L++ K  ++  M++L  R+ +GL  + + +   +  +G   +E       +  TP  Y+  +I++    N   + +  N+  F   ++  F  FIN N         S+SPE L+ Y D  LK+ +K   + +++ I +  +++F+Y++DKD+F+++Y   LAKRL+   S SDD E SMISKL   CG  +TSKL+ MF+D+ +SK L ++F + L    T +L +D  ++VL++G WP Q  + T  +P E + +
Sbjct:    6 ANPHGLRQINLDEIWDDLKEGIQHVYNQQSMSKQRYMELYTHVYNYCTSVHQQSQSRVPKQKKAPNQGGAQFVGHELYKRLKEFLKSYLLNMQKDGADLMDESVLRFYSSRWEDYRFSSKVLNGVCAYLNRHWVRRECDEGRKGIYEIYQLALVTWREHLFR--PLNKQVTNAVLRLIERERNGETINTRLVSGVIQCYVELGLNEEEQSSKGPALTVYKQYFESVFLEDTERFYTAESVEFLRENPVTEYMKKAEARLLEEQRRVNVYLHESTQDELARKCEQVLIEKHLD-IFYAE---FQNLLNDDKNEDLGRMYSLGSRIPDGLVQLRTLLENHICYQGLNALEKCGEQAYNVSTPASYVIIIIFVSKMCNYYFIMSFKNDAGFVAALDKAFGKFINSNAVTKQAQASSKSPELLARYCDSLLKKSSKNPEEAELEDILNSVMVVFKYIEDKDVFQKFYANMLAKRLVQHNSASDDAEASMISKLKQACGFEYTSKLQRMFQDIGVSKDLNDKFKAHLA--NTGSLDLDFTIQVLSSGSWPFQQ-SWTFSLPAEMEKS 558
[Close]
BLAST of Cullin 3 vs. Ensembl Nematostella
Match: EDO49091 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RI48])

HSP 1 Score: 173.326 bits (438), Expect = 1.338e-46
Identity = 137/533 (25.70%), Postives = 265/533 (49.72%), Query Frame = 1 
Query:  103 DQSVSKIWECLKRAIIEIQKKNNSGLSFEELYRNAYTMVL---QKNGEQLYNGTKAVVTDHMIKIRDEVLERLTNNFLAFLNRCWKDHITAMVMIRDILMYMDR-------------VYVTTTDKPNVYNTGMI---IFRDTVLRHEAIRRHLRVTLLDMVKRERHGEVISRLQLRDACQMLAQLGVDK------LNIYEEDFENYFLEQSRDFYRSESERLLTENASNLYITQVNKIIEDEAKRARDFLNSTTEAKIVQVLNEELIKNHIESVVNTENFGLTHMLSNKKYSEIALMFNLLKRVDNGLATMCSCISRFLREEGRKIVEDD----KTPQIYIQELIYXXXXXXXXXXXXXXXXQLFKNQINSDFEFFIN------QNSRSPEYLSLYIDDKLKRGTKGISDQDIDAIFDKCIILFRYLQDKDIFERYYKQHLAKRLLMSKSQSDDQEKSMISKLLIECGGVFTSKLEGMFKDMAISKTLMEEFHSQLQMYTTNTLGIDLFVRVLTTGLWP-TQTATQTVCMPDE 1593
            D++ +KI + LK A++ ++K   +   + + + + Y + +   +  GE+LY+  K  + +H +K   + +     + L   +  W  +      +  +  Y++               Y  T   P+  + G +   I++  ++  E ++  L   LL  ++++R+GE   +  + D  +    +GV +      L++YE +FE   L+++ ++YR E+  LL EN  ++YI +V+  I+DE  RAR FL+  + +++++     +++ HI  +          M+  +K ++++ M+ LLK +  GL  M + + + + E G+          + P  Y+  ++ +  +   L+      +Q F   ++      +N      + S+SPE L+ Y D  LK+  K +SD ++D    + II+F+Y+ DKDIF+++Y + LAKRL+ + S S D E++MIS+L   CG  +T++L  MF DM+IS  L   F   L     N +GI+  + VL +G WP  QT+     +P E
Sbjct:   11 DETWAKILKTLK-AVVTLEKIERA--VWNDRFSDVYALCVAYPEPLGEKLYSEIKLFLEEH-VKSLYQAVSSPDIDILREYHSHWAKYSQGSSYMDLLFRYLNSHLKKQKQDYVEISPYTVTPICPDAIDIGPLALSIWKSIMI--EPLKETLVQHLLAEIRKDRNGEGTQQNVVHDTIKSF--VGVQEYQSKGALSLYESEFEKPLLQETGEYYRREAADLLAENPCSVYIQKVDVRIQDEDLRARKFLHPVSYSRVIRECEARMVEEHIPYL----QAECRQMVRGEKCADLSRMYKLLKHIPRGLHVMVTELEQHVEETGQNHDTQKFICFQGPFQYVDAMLDVHSKFTKLIDETFHADQAFHASLDKACTTIVNYRHDARKPSKSPELLAKYCDLILKKSNKNLSDSELDEKLGEVIIVFKYIDDKDIFQKFYSKMLAKRLIHNLSISMDAEEAMISRLKHACGYEYTNRLHWMFTDMSISSDLNSSFSDFLATAQVN-MGINFSLLVLQSGAWPLGQTSVSPFSIPQE 530
[Close]
BLAST of Cullin 3 vs. Ensembl Nematostella
Match: EDO46074 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RQY8])

HSP 1 Score: 115.546 bits (288), Expect = 3.529e-29
Identity = 72/245 (29.39%), Postives = 120/245 (48.98%), Query Frame = 1 
Query:   97 MSDQSVSKIWECLKRAIIEIQKKNNSGLSFEELYRNAYTMVLQKNGEQLYNGTKAVVTDH----MIKIRDEVLERLTNN------FLAFLNRCWKDHITAMVMIRDILMYMDRVYV-TTTDKPNVYNTGMIIFRDTVLRHEAIRRHLRVTLLDMVKRERHGEVISRLQLRDACQMLAQLGVDKLNIYEEDFENYFLEQSRDFYRSESERLLTENASNLYITQVNKIIEDEAKRARDFLNSTTEAK 798
            + D      W  LK A+  I  K +   S EELY+    M   K    LY+  KA    H    +++      + L ++      +L  L +CW+ H   M+MIR I +Y+DR YV   T   ++++ G+ +FR  ++ +  ++R     LL M+++ERHGE + R  L+   +MLA      + +YE+ FE+ FLE +   Y  E  R + E     Y+  V+K +++E  R   +L+ +T  K
Sbjct:   14 LPDNYKEATWLKLKEAVCAIHHKTSIQYSLEELYKAVENMCSHKMAATLYSQLKAECEQHVKSNLVQFTGYPFQFLGHHSMDSVLYLGKLKQCWEGHCRQMIMIRSIFLYLDRTYVLQNTSILSLWDMGLHLFRSHIMVNPIVQRRTVDGLLQMIEKERHGEAVDRSLLKSLLRMLAD-----IQMYEDAFESKFLEATDVLYSQEGNRYMQETDVPKYLAHVDKRLKEEMDRLIHYLDQSTRYK 253
[Close]
BLAST of Cullin 3 vs. Ensembl Medaka
Match: CUL3 (cullin-3-like [Source:NCBI gene;Acc:101170875])

HSP 1 Score: 593.193 bits (1528), Expect = 0.000e+0
Identity = 289/522 (55.36%), Postives = 388/522 (74.33%), Query Frame = 1 
Query:   64 SKMRIKAFPTSMSDQSVSKIWECLKRAIIEIQKKNNSGLSFEELYRNAYTMVLQKNGEQLYNGTKAVVTDHMI-KIRDEVLERLTNNFLAFLNRCWKDHITAMVMIRDILMYMDRVYVTTTDKPNVYNTGMIIFRDTVLRHEAIRRHLRVTLLDMVKRERHGEVISRLQLRDACQMLAQLGVDKLNIYEEDFENYFLEQSRDFYRSESERLLTENASNLYITQVNKIIEDEAKRARDFLNSTTEAKIVQVLNEELIKNHIESVVNTENFGLTHMLSNKKYSEIALMFNLLKRVDNGLATMCSCISRFLREEGRKIVEDD---KTPQIYIQELIYXXXXXXXXXXXXXXXXQLFKNQINSDFEFFINQNSRSPEYLSLYIDDKLKRGTKGISDQDIDAIFDKCIILFRYLQDKDIFERYYKQHLAKRLLMSKSQSDDQEKSMISKLLIECGGVFTSKLEGMFKDMAISKTLMEEFHSQLQMYTTNTLGIDLFVRVLTTGLWPTQTATQTVCMPDEAQNAFSIY 1617
            +KMRI+AFP +M ++ V+ IW+ LK AI EIQ+KNNSGLSFEELYRNAYTMVL K+GE+LY G + VVT+H+I K+R++VL  L NNFL  LN+ W DH TAMVMIRDILMYMDRVYV   +  NVYN G+IIFRD V+R+  IR HLR TLLDM+ RER GEV+ R  +R+A QML  LG+D  ++YEEDFE  FL+ S +F++ ES++ L EN++++YI +V   I +E +R    L+ +TE  IV+V+  ELI  H++++V  EN GL HML N K  ++A M+ L  RV NGL TMC C+S +LRE+G+ +V ++   K P  YIQ L+ L+ R +  L+ +  N++LFK  I  DFE+F+N NSRSPEYLSL+IDDKLK+G KG+++Q++++I DK ++LFR++Q+KD+FERYYKQHL +RLL +KS SDD EK+MISKL  ECG  FTSKLEGMF+DM+IS T M+EF   +Q  + +  G+DL VRVLTTG WPTQ+AT    +P   ++AF ++
Sbjct:   12 TKMRIRAFPMTMDEKYVNNIWDLLKSAIQEIQRKNNSGLSFEELYRNAYTMVLHKHGERLYTGLREVVTEHLINKVREDVLNSLNNNFLQTLNQAWNDHQTAMVMIRDILMYMDRVYVQQNNVENVYNLGLIIFRDQVVRYGCIRDHLRQTLLDMIARERKGEVVDRGAIRNASQMLMILGLDGRSVYEEDFEGPFLDMSAEFFQMESQKFLAENSASVYIKKVEARINEEIERVMHCLDKSTEEPIVKVVERELISKHMKTIVEMENSGLVHMLKNSKTEDLACMYKLFSRVPNGLKTMCECMSSYLREQGKALVSEEGEGKNPVDYIQGLLDLKTRFDHFLIESFNNDRLFKQTIAGDFEYFLNLNSRSPEYLSLFIDDKLKKGVKGLTEQEVESILDKAMVLFRFMQEKDVFERYYKQHLGRRLLSNKSVSDDSEKNMISKLKTECGCQFTSKLEGMFRDMSISNTTMDEFRQHIQTTSASLSGVDLTVRVLTTGYWPTQSATPKCTIPPAPRHAFEVF 533
[Close]
BLAST of Cullin 3 vs. Ensembl Medaka
Match: cul3b (cullin-3 [Source:NCBI gene;Acc:101172920])

HSP 1 Score: 580.096 bits (1494), Expect = 0.000e+0
Identity = 285/512 (55.66%), Postives = 379/512 (74.02%), Query Frame = 1 
Query:   94 SMSDQSVSKIWECLKRAIIEIQKKNNSGLSFEELYRNAYTMVLQKNGEQLYNGTKAVVTDHMI-KIRDEVLERLTNNFLAFLNRCWKDHITAMVMIRDILMYMDRVYVTTTDKPNVYNTGMIIFRDTVLRHEAIRRHLRVTLLDMVKRERHGEVISRLQLRDACQMLAQLGVDKLNIYEEDFENYFLEQSRDFYRSESERLLTENASNLYITQVNKIIEDEAKRARDFLNSTTEAKIVQVLNEELIKNHIESVVNTENFGLTHMLSNKKYSEIALMFNLLKRVDNGLATMCSCISRFLREEGRKIVEDD---KTPQIYIQELIYXXXXXXXXXXXXXXXXQLFKNQINSDFEFFINQNSRSPEYLSLYIDDKLKRGTKGISDQDIDAIFDKCIILFRYLQDKDIFERYYKQHLAKRLLMSKSQSDDQEKSMISKLLIECGGVFTSKLEGMFKDMAISKTLMEEFHSQLQMYTTNTLGIDLFVRVLTTGLWPTQTATQTVCMPDEAQNAFSIY 1617
            +M ++ V+ IW+ LK AI EIQ+KNNSGLSFEELYRNAYTMVL K+GE+LY G + VVT+H+I K+R++VL  L NNFL  LN+ W DH TAMVMIRDILMYMDRVYV   +  NVYN G+IIFRD V+R+  IR HLR TLLDM+ RER GEV+ R  +R+ACQML  LG++  ++YEEDFE  FLE S +F++ ES++ L EN++++YI +V   I +E +R    L+ +TE  IV+V+  ELI  H++++V  EN GL HML N K  ++A M+ L  RV NGL TMC C+S +LRE+G+ +V ++   K P  YIQ L+ L+ R +  L  +  N++LFK  I  DFE+F+N NSRSPEYLSL+IDDKLK+G KG+++Q++++I DK ++LFR++Q+KD+FERYYKQHLA+RLL +KS SDD EK+MISKL  ECG  FTSKLEGMF+DM+IS T M+EF   LQ    +  G+DL VRVLTTG WPTQ+AT    +P   ++AF ++
Sbjct:    2 TMDEKYVNNIWDLLKNAIQEIQRKNNSGLSFEELYRNAYTMVLHKHGEKLYTGLREVVTEHLINKVREDVLNSLNNNFLQTLNQAWNDHQTAMVMIRDILMYMDRVYVQQNNVENVYNLGLIIFRDQVVRYGCIRDHLRQTLLDMIARERKGEVVDRGAIRNACQMLMILGLEGRSVYEEDFEAPFLEMSAEFFQMESQKFLAENSASVYIKKVEARINEEIERVMHCLDKSTEEPIVKVVERELISKHMKTIVEMENSGLVHMLKNGKTDDLACMYKLFSRVPNGLKTMCECMSAYLREQGKALVSEEGEGKNPVDYIQGLLDLKSRFDRFLQESFNNDRLFKQTIAGDFEYFLNLNSRSPEYLSLFIDDKLKKGVKGLTEQEVESILDKAMVLFRFMQEKDVFERYYKQHLARRLLTNKSVSDDSEKNMISKLKTECGCQFTSKLEGMFRDMSISNTTMDEFRQHLQTTGVSLGGVDLTVRVLTTGYWPTQSATPKCNIPPSPRHAFEVF 513
[Close]
BLAST of Cullin 3 vs. Ensembl Medaka
Match: CUL3 (cullin-3-like [Source:NCBI gene;Acc:101170875])

HSP 1 Score: 576.244 bits (1484), Expect = 0.000e+0
Identity = 282/512 (55.08%), Postives = 379/512 (74.02%), Query Frame = 1 
Query:   94 SMSDQSVSKIWECLKRAIIEIQKKNNSGLSFEELYRNAYTMVLQKNGEQLYNGTKAVVTDHMI-KIRDEVLERLTNNFLAFLNRCWKDHITAMVMIRDILMYMDRVYVTTTDKPNVYNTGMIIFRDTVLRHEAIRRHLRVTLLDMVKRERHGEVISRLQLRDACQMLAQLGVDKLNIYEEDFENYFLEQSRDFYRSESERLLTENASNLYITQVNKIIEDEAKRARDFLNSTTEAKIVQVLNEELIKNHIESVVNTENFGLTHMLSNKKYSEIALMFNLLKRVDNGLATMCSCISRFLREEGRKIVEDD---KTPQIYIQELIYXXXXXXXXXXXXXXXXQLFKNQINSDFEFFINQNSRSPEYLSLYIDDKLKRGTKGISDQDIDAIFDKCIILFRYLQDKDIFERYYKQHLAKRLLMSKSQSDDQEKSMISKLLIECGGVFTSKLEGMFKDMAISKTLMEEFHSQLQMYTTNTLGIDLFVRVLTTGLWPTQTATQTVCMPDEAQNAFSIY 1617
            +M ++ V+ IW+ LK AI EIQ+KNNSGLSFEELYRNAYTMVL K+GE+LY G + VVT+H+I K+R++VL  L NNFL  LN+ W DH TAMVMIRDILMYMDRVYV   +  NVYN G+IIFRD V+R+  IR HLR TLLDM+ RER GEV+ R  +R+A QML  LG+D  ++YEEDFE  FL+ S +F++ ES++ L EN++++YI +V   I +E +R    L+ +TE  IV+V+  ELI  H++++V  EN GL HML N K  ++A M+ L  RV NGL TMC C+S +LRE+G+ +V ++   K P  YIQ L+ L+ R +  L+ +  N++LFK  I  DFE+F+N NSRSPEYLSL+IDDKLK+G KG+++Q++++I DK ++LFR++Q+KD+FERYYKQHL +RLL +KS SDD EK+MISKL  ECG  FTSKLEGMF+DM+IS T M+EF   +Q  + +  G+DL VRVLTTG WPTQ+AT    +P   ++AF ++
Sbjct:    2 TMDEKYVNNIWDLLKSAIQEIQRKNNSGLSFEELYRNAYTMVLHKHGERLYTGLREVVTEHLINKVREDVLNSLNNNFLQTLNQAWNDHQTAMVMIRDILMYMDRVYVQQNNVENVYNLGLIIFRDQVVRYGCIRDHLRQTLLDMIARERKGEVVDRGAIRNASQMLMILGLDGRSVYEEDFEGPFLDMSAEFFQMESQKFLAENSASVYIKKVEARINEEIERVMHCLDKSTEEPIVKVVERELISKHMKTIVEMENSGLVHMLKNSKTEDLACMYKLFSRVPNGLKTMCECMSSYLREQGKALVSEEGEGKNPVDYIQGLLDLKTRFDHFLIESFNNDRLFKQTIAGDFEYFLNLNSRSPEYLSLFIDDKLKKGVKGLTEQEVESILDKAMVLFRFMQEKDVFERYYKQHLGRRLLSNKSVSDDSEKNMISKLKTECGCQFTSKLEGMFRDMSISNTTMDEFRQHIQTTSASLSGVDLTVRVLTTGYWPTQSATPKCTIPPAPRHAFEVF 513
[Close]
BLAST of Cullin 3 vs. Ensembl Medaka
Match: cul4b (cullin 4B [Source:NCBI gene;Acc:101161413])

HSP 1 Score: 274.248 bits (700), Expect = 3.459e-82
Identity = 173/525 (32.95%), Postives = 290/525 (55.24%), Query Frame = 1 
Query:   37 LDSSVSSNPSKMRIKAF--PTSMSDQSVSKIWECLKRAIIEIQKKNNSGLSFEELYRNAYTMVLQKNGEQLYNGTKAVVTDHMIKIRDEVLERLTNN--FLAFLNRCWKDHITAMVMIRDILMYMDRVYVTTTDK-PNVYNTGMIIFRDTVLRHEAIRRHLRVTLLDMVKRERHGEVISRLQLRDACQMLAQLGVDKLNIYEEDFENYFLEQSRDFYRSESERLLTENASNLYITQVNKIIEDEAKRARDFLNSTTEAKIVQVLNEELIKNHIESVVNTENFGLTHMLSNKKYSEIALMFNLLKRVDNGLATMCSCISRFLREEGRKIVEDDKTPQIYIQELIYXXXXXXXXXXXXXXXXQLFKNQINSDFEFFINQNSRSP-EYLSLYIDDKLKRGTKGISDQDIDAIFDKCIILFRYLQDKDIFERYYKQHLAKRLLMSKSQSDDQEKSMISKLLIECGGVFTSKLEGMFKDMAISKTLMEEFHSQLQMYTTNTLGIDLFVRVLTTGLWPTQTATQTVCMPDE 1593
              SS      K+ IK F     + +    + W+ LK A+  IQ   +   + EELY+    +   K   +LY   +A   DH+    D+  E   ++  FL  +++CW+DH   M+MIR I +++DR YV      P++++ G+ +FR  ++    ++      +L +++RER+GE I R  LR    ML+ L      IY++ FE  FLE++   Y +E +RL+ E     Y+  V+K +E+EA R   +L+ +T+  ++  + ++L+  H+ + +     GLT +L   +  +++L++ L  RV  G+  +      +++  G  IV + +  +  +QEL+  +D+ + ++    + N+ F N +   FE FIN+    P E ++ ++D KL+ G K  +D++++ + DK +I+FR++  KD+FE +YK+ LAKRLL+ KS S D EKSM+SKL  ECG  FTSKLEGMFKDM +SK +M +F  Q Q    N   I+L V +LT G WPT    + V +P E
Sbjct:  136 FSSSKPGAAKKLVIKNFREKPKLPENYTQETWQKLKEAVEAIQNSTSIKYNLEELYQAVENLCFHKVSAKLYKQLRAACEDHIKAQIDQFREDALDSVLFLKKIDKCWQDHCRQMIMIRSIFLFLDRTYVLQNSMLPSIWDMGLELFRFYIISDLKVQSKTINGILLLIERERNGEAIDRSLLRSLLSMLSDL-----QIYQDSFEQRFLEETNRLYAAEGQRLMQEREVPEYLHHVSKRLEEEADRVITYLDQSTQKPLIATVEKQLLGEHLTATLQK---GLTQLLDENRIQDLSLLYQLFSRVRGGVQVLLQHWIEYIKAFGSTIVINPEKDKTMVQELLDFKDKVDHIMDVCFIRNEKFVNAMKEAFETFINKRPNKPAELIAKHVDSKLRAGNKEATDEELEKMLDKIMIIFRFIYGKDVFEAFYKKDLAKRLLVGKSASVDAEKSMLSKLKHECGAAFTSKLEGMFKDMELSKDIMVQF-KQCQNIPGN---IELTVNILTMGYWPTYVPME-VHLPPE 647
[Close]
BLAST of Cullin 3 vs. Ensembl Medaka
Match: cul4a (cullin-4A [Source:NCBI gene;Acc:101154851])

HSP 1 Score: 245.358 bits (625), Expect = 2.762e-73
Identity = 140/420 (33.33%), Postives = 247/420 (58.81%), Query Frame = 1 
Query:  373 MIRDILMYMDRVYVTTTDK-PNVYNTGMIIFRDTVLRHEAIRRHLRVTLLDMVKRERHGEVISRLQLRDACQMLAQLGVDKLNIYEEDFENYFLEQSRDFYRSESERLLTENASNLYITQVNKIIEDEAKRARDFLNSTTEAKIVQVLNEELIKNHIESVVNTENFGLTHMLSNKKYSEIALMFNLLKRVDNGLATMCSCISRFLREEGRKIVEDDKTPQIYIQELIYXXXXXXXXXXXXXXXXQLFKNQINSDFEFFINQNSRSP-EYLSLYIDDKLKRGTKGISDQDIDAIFDKCIILFRYLQDKDIFERYYKQHLAKRLLMSKSQSDDQEKSMISKLLIECGGVFTSKLEGMFKDMAISKTLMEEFHSQLQMYTTNTLGIDLFVRVLTTGLWPTQTATQTVCMPDEA---QNAFSIY 1617
            MIR I +++DR YV      P++++TG+ +FR  ++   A+++     +L+ ++ ER+GE + R  LR    ML+ L      +Y++ FE  FL ++   Y +E +RL+ E     Y+  V + +E+E  R   +L+ +T+  ++  + ++L+  H+ +++     GL+++L   + +E+AL++ L  +V  GL T+      +++  G +IV   +  +  +Q+L+  +D+ +++  +    N+ F N +   FE FIN+    P E ++ Y+D KL+ G K  ++++++ I DK +I+FR++  KD+FE +YK+ LAKRLL+ KS S D EKSM+SKL  ECG  FTSKLEGMFKDM +SK +M +F   +Q  +  +  I+L V +LT G WP+ T  + V +P E    Q  F ++
Sbjct:    1 MIRSIFLFLDRTYVLQNSLLPSIWDTGLELFRTHIVSDSAVQKRTVEAILEQIELERNGETVDRSLLRSLLGMLSDL-----QVYKDSFEERFLAETDRLYAAEGQRLMQERDVPEYLHHVARRLEEENDRILSYLDQSTQKPLICCVEKQLLGEHMTAILQK---GLSNLLDENRVTELALLYQLFSKVKGGLPTLLQFWRDYIKSFGGEIVCTPEKDKDMVQDLLDFKDKMDNVAQSCFGRNEGFINAMKEAFETFINKRPNKPAELIAKYVDSKLRAGNKEATEEELERILDKIMIIFRFIHGKDVFEAFYKKDLAKRLLVGKSASVDAEKSMLSKLKHECGAAFTSKLEGMFKDMELSKDIMIQFKQHMQNQSEPS-NIELTVNILTMGYWPSYTPME-VHLPAEMVKLQEVFKLF 410
[Close]
BLAST of Cullin 3 vs. Planmine SMEST
Match: SMESG000001134.1 (SMESG000001134.1)

HSP 1 Score: 1070.84 bits (2768), Expect = 0.000e+0
Identity = 534/535 (99.81%), Postives = 534/535 (99.81%), Query Frame = 1 
Query:   16 MSGNIRKLDSSVSSNPSKMRIKAFPTSMSDQSVSKIWECLKRAIIEIQKKNNSGLSFEELYRNAYTMVLQKNGEQLYNGTKAVVTDHMIKIRDEVLERLTNNFLAFLNRCWKDHITAMVMIRDILMYMDRVYVTTTDKPNVYNTGMIIFRDTVLRHEAIRRHLRVTLLDMVKRERHGEVISRLQLRDACQMLAQLGVDKLNIYEEDFENYFLEQSRDFYRSESERLLTENASNLYITQVNKIIEDEAKRARDFLNSTTEAKIVQVLNEELIKNHIESVVNTENFGLTHMLSNKKYSEIALMFNLLKRVDNGLATMCSCISRFLREEGRKIVEDDKTPQIYIQELIYXXXXXXXXXXXXXXXXQLFKNQINSDFEFFINQNSRSPEYLSLYIDDKLKRGTKGISDQDIDAIFDKCIILFRYLQDKDIFERYYKQHLAKRLLMSKSQSDDQEKSMISKLLIECGGVFTSKLEGMFKDMAISKTLMEEFHSQLQMYTTNTLGIDLFVRVLTTGLWPTQTATQTVCMPDEAQNAFSIYS 1620
            MSGNIRKLDSSVSSNPSKMRIKAFPTSMSDQSVSKIWECLKRAIIEIQKKNNSGLSFEELYRNAYTMVLQKNGEQLYNGTKAVVTDHMIKIRDEVLERLTNNFLAFLNRCWKDHITAMVMIRDILMYMDRVYVTTTDKPNVYNTGMIIFRDTVLRHEAIRRHLRVTLLDMVKRERHGEVISRLQLRDACQMLAQLGVDKLNIYEEDFENYFLEQSRDFYRSESERLLTENASNLYITQVNKIIEDEAKRARDFLNSTTEAKIVQVLNEELIKNHIESVVNTENFGLTHMLSNKKYSEIALMFNLLKRVDNGLATM SCISRFLREEGRKIVEDDKTPQIYIQELIYLRDRANDLLLNALLNNQLFKNQINSDFEFFINQNSRSPEYLSLYIDDKLKRGTKGISDQDIDAIFDKCIILFRYLQDKDIFERYYKQHLAKRLLMSKSQSDDQEKSMISKLLIECGGVFTSKLEGMFKDMAISKTLMEEFHSQLQMYTTNTLGIDLFVRVLTTGLWPTQTATQTVCMPDEAQNAFSIYS
Sbjct:    1 MSGNIRKLDSSVSSNPSKMRIKAFPTSMSDQSVSKIWECLKRAIIEIQKKNNSGLSFEELYRNAYTMVLQKNGEQLYNGTKAVVTDHMIKIRDEVLERLTNNFLAFLNRCWKDHITAMVMIRDILMYMDRVYVTTTDKPNVYNTGMIIFRDTVLRHEAIRRHLRVTLLDMVKRERHGEVISRLQLRDACQMLAQLGVDKLNIYEEDFENYFLEQSRDFYRSESERLLTENASNLYITQVNKIIEDEAKRARDFLNSTTEAKIVQVLNEELIKNHIESVVNTENFGLTHMLSNKKYSEIALMFNLLKRVDNGLATMSSCISRFLREEGRKIVEDDKTPQIYIQELIYLRDRANDLLLNALLNNQLFKNQINSDFEFFINQNSRSPEYLSLYIDDKLKRGTKGISDQDIDAIFDKCIILFRYLQDKDIFERYYKQHLAKRLLMSKSQSDDQEKSMISKLLIECGGVFTSKLEGMFKDMAISKTLMEEFHSQLQMYTTNTLGIDLFVRVLTTGLWPTQTATQTVCMPDEAQNAFSIYS 535
[Close]
BLAST of Cullin 3 vs. Planmine SMEST
Match: SMESG000033325.1 (SMESG000033325.1)

HSP 1 Score: 692.575 bits (1786), Expect = 0.000e+0
Identity = 353/537 (65.74%), Postives = 439/537 (81.75%), Query Frame = 1 
Query:   16 MSGNIRKLDSSVSSNPSKMRIKAFPTSMSDQSVSKIWECLKRAIIEIQKKNNSGLSFEELYRNAYTMVLQKNGEQLYNGTKAVVTDHMIKIRDEVLERLTNNFLAFLNRCWKDHITAMVMIRDILMYMDRVYVTTTDKPNVYNTGMIIFRDTVLRHEAIRRHLRVTLLDMVKRERHGEVISRLQLRDACQMLAQLGVDKLNIYEEDFENYFLEQSRDFYRSESERLLTE-NASNLYITQVNKIIEDEAKRARDFLNSTTEAKIVQVLNEELIKNHIESVVNTENFGLTHMLSNKKYSEIALMFNLLKRVDNGLATMCSCISRFLREEGRKIVEDD-KTPQIYIQELIYXXXXXXXXXXXXXXXXQLFKNQINSDFEFFINQNSRSPEYLSLYIDDKLKRGTKGISDQDIDAIFDKCIILFRYLQDKDIFERYYKQHLAKRLLMSKSQSDDQEKSMISKLLIECGGVFTSKLEGMFKDMAISKTLMEEFHSQLQMYTTNTLGIDLFVRVLTTGLWPTQTATQTVCMPDEAQNAFSIYS 1620
            MS N RK ++S+SSN +KMRIKAFP S++DQ V KIWE LK+AI+EIQKKNNSGLSFEELYRNAYTMVLQK+GE+LYNGTK VVT+H+ KI+++VLE L NNFL +LN+CWKDH TAMVMIRDILMYMDRVYV  T+K NVYNTG+IIFRD VLR+  IR  L+  LL+MV +ER GEVI++ Q+RDACQML QLGV+   IYEEDFE  FL+QS++FYR ESE  L+E N S +YI +V + IE+E+KRAR +L+ +TE KIV+VL EELI  HI+ +VN  + GL +ML+ K+++ IA M+ LL RVDNGL  M  CIS FLRE+GR +V D+ K+P  ++ EL+ LRD+A+ LL  AL N+ LF+NQIN+DFE+FIN NSRSPEYLSL+IDDKL+RGTKG+ D D++A+FDKCI+LFRYLQDKD+FERYYKQHLAKRLL  KSQSDDQEKSMISKL++ECGGVFTSKLEGMFKDMAISK LM+++ + ++    N  G+DL+VRVLTTGLWPTQ+    + + +E Q+AF  Y+
Sbjct:    1 MSSNTRKFEASLSSNSNKMRIKAFPASLNDQYVGKIWETLKKAIVEIQKKNNSGLSFEELYRNAYTMVLQKHGEKLYNGTKVVVTEHLQKIKEQVLENLNNNFLNYLNQCWKDHHTAMVMIRDILMYMDRVYVAQTEKQNVYNTGLIIFRDIVLRNVEIRESLQSNLLNMVAKERKGEVIAKSQIRDACQMLVQLGVNSTLIYEEDFEKVFLDQSKEFYRLESESFLSENNLSIMYINRVEQRIEEESKRARHYLDPSTEPKIVKVLEEELISKHIDEIVNMSHSGLNYMLNEKQHTNIASMYKLLSRVDNGLQMMSQCISSFLREQGRAVVVDESKSPIAFVTELLTLRDKASTLLTEALDNHSLFRNQINADFEYFINHNSRSPEYLSLFIDDKLRRGTKGMDDPDVEAVFDKCIVLFRYLQDKDVFERYYKQHLAKRLLTMKSQSDDQEKSMISKLIVECGGVFTSKLEGMFKDMAISKILMDDWLNSIK--PANNTGVDLYVRVLTTGLWPTQSLNINISLSEEVQSAFDAYA 535
[Close]
BLAST of Cullin 3 vs. Planmine SMEST
Match: SMESG000008644.1 (SMESG000008644.1)

HSP 1 Score: 163.696 bits (413), Expect = 1.038e-42
Identity = 127/512 (24.80%), Postives = 248/512 (48.44%), Query Frame = 1 
Query:  232 GEQLYNGTKAVVTDHMIKIRDEVLERLTNNFLAFLNRCWKDHITAMVMIRDILMYMDRVYVTTTDKP------NVYNTGMIIFRDTVLR-HEAI-------------------RRHLRVTLLDMVKRERHGEVISRL-------QLRDACQMLAQLGVD-------KLNIYEEDFENYFLEQSRDFYRSESERLLTENASNLYITQVNKIIEDEAKRARDFLNSTTEAKIVQ----VLNEELIKNHIESVVNTENFGLTHMLSNKKYSEIALMFNLLKRVDNGLATMCSCISRFLREEGRKIVEDDKT-----PQIYIQELIYXXXXXXXXXXXXXXXXQLFKNQINSDFEFFINQNS---------RSPEYLSLYIDDKLKRGTKGISDQDIDAIFDKCIILFRYLQDKDIFERYYKQHLAKRLLMSKSQSDDQEKSMISKLLIECGGVFTSKLEGMFKDMAISKTLMEEFHSQLQMYTTNTLGIDLFVRVLTTGLWPTQTATQTVCMPDE 1593
            G +LY   K  + +H+IK++ +   +     L F+   W ++  ++ ++  + MY++R +V    +       ++Y   ++ + + +LR H+ I                    R L+  +  +V+  R G    ++       Q  D   ++ Q   D        L++Y + FE  F++++  FYR ES   L +N    Y+ +V   + +E +R   F++     K ++    VL + L+ +H++ ++N      T +L+ ++ S++  MF LL ++     +M S    F+ ++G + +    T     P++YI+ ++ +  +    +  A      F   ++   E FIN+N+         ++PE+L+ Y D  LK+ ++  +  D+D I  + + +F+Y++DKD+F+ +Y + LA+RL+   S S+D E +MIS+L   CG  +T+KL+ MF D + S+ L  +F    Q  + N   IDL V VL++  WP  TA +   +P E
Sbjct:   88 GWELYKKLKEYLKNHVIKLKIKGDGKTDEEMLKFIQSSWTEYSFSVKVLNGVCMYLNRNWVKRQLEEGHKQFHDIYTCALLAWTENLLRPHQTIISDALIKEVEKERLDEQLNHRFLKPIIDCLVEVGRVGGSTPKITGTLGQSQHSDNSTLIGQADHDVSMKMNFDLSVYVKIFETPFIKKTERFYRIESMDFLAKNEITDYLKKVEDRMAEEEQRINSFIHFAPRNKTLEELNSVLTKTLLADHLDRIINE----FTPLLAAERISDLRRMFTLLYKIPEAFISMTSHFENFVYQKGNEAISSKSTDNLPEPKVYIETILDVYKKNYATVTEAFHGEIRFLKALDKGCERFINKNAVTEMAKTSRKTPEFLAKYCDMLLKKSSRDTNTDDLDEILSRFMTVFKYIEDKDVFQGFYSKMLARRLINDLSISEDIEAAMISRLKESCGYEYTAKLQRMFSDKSTSRDLNAKFLISPQNKSGN---IDLNVMVLSSNSWP-YTAQEKFTLPQE 591
[Close]
BLAST of Cullin 3 vs. Planmine SMEST
Match: SMESG000054773.1 (SMESG000054773.1)

HSP 1 Score: 157.147 bits (396), Expect = 2.321e-41
Identity = 118/431 (27.38%), Postives = 227/431 (52.67%), Query Frame = 1 
Query:  388 LMYMDRVYVTTTDK-PNVYNTGMIIFRDTVLRHEAIRRHLRVTLLDMVKRERHGEVISRLQLRDACQMLAQLGVDKLNIYEEDFENYFLEQSRDFYRSESERLLTENASNLYITQVNKIIEDEAKRARDFLNS-TTEAKIVQVLNEELIKNHIESVVNTENFGLTHMLSNKKYSEIALMFNLLKRVDN------GLATMCSCISRFLREEGRKIVE----DDKTPQIYIQELIYXXXXXXXXXXXXXXXXQLFKNQINSDFEFFINQNSRSP-EYLSLYIDDKLKRGTKGISDQDIDAIFDKCIILFRYLQDKDIFERYYKQHLAKRLLMSKSQSDDQEKSMISKLLIECGGVFTSKLEGMFKDMAISKTLMEEFHSQLQMYTT-----NTLGIDLFVRVLTTGLWPTQTATQTVCMPD---EAQNAFSIY 1617
            ++++DR + +      + ++  M ++RD  +    I + + V  L  +  +R G + S L L  A   +AQ+ +D L++Y+  +E  +L+++R +Y  ESER L E ++  Y+  VN  +++E +R++ +L+  +   ++   L   ++K H++ ++ +   G  HM+ N     + L++NL + +++      G+  + +    ++ + G  IVE    D +  +   Q  + L+   + ++      +  F   I   FE F+N     P EYL+ ++D KL+ G K ++++ ++ I DK + LFR++  KD+FE +Y + LAKRLLM KS   D EK+M+ KL  ECG  +T K+E MF D+  S+ L ++F     +        N + I++ V V+    WP+   ++ + +P    + QNAFS +
Sbjct:    1 MLFVDRKFWSNNSSLMSFWDMAMQLWRDMYITGPLINKEI-VLCLKQIHNQRDG-ISSDLSLSKA---VAQMFID-LDLYQRFWEPKYLDEARSYYSQESERKLKELSNTDYLVYVNTRLDEENERSQMYLSGDSIRIQLRDQLVNIILKPHLDELLKS---GFNHMMENNDIFYLELLYNLAQLLNSKSADSSGIYILRNYFKEYVMKSGTLIVENPNDDVEKDKKMTQNFLDLKVHLDSVVEKCFKGDMSFYKTIRDCFEAFLNARPNKPAEYLAKFLDSKLRSGNKNLTEEAMELIMDKVMTLFRFITGKDVFEAFYLKDLAKRLLMGKSACVDTEKAMLEKLKHECGPNYTRKMEIMFSDIDNSQRLSKQFSDSNSLQNIIDKDMNKVNIEMNVNVICNATWPSLGGSKLLNIPQYMIDMQNAFSAF 422
[Close]
BLAST of Cullin 3 vs. Planmine SMEST
Match: SMESG000001104.1 (SMESG000001104.1)

HSP 1 Score: 150.599 bits (379), Expect = 1.201e-38
Identity = 120/453 (26.49%), Postives = 228/453 (50.33%), Query Frame = 1 
Query:  322 FLAFLNRCWKDHITAMVMIRDILMYMDRVYVTTTDK-PNVYNTGMIIFRDTVLRHEAIRRHLRVTLLDMVKRERHGEVISRLQLRDACQMLAQLGVDKLNIYEEDFENYFLEQSRDFYRSESERLLTENASNLYITQVNKIIEDEAKRARDFLNS-TTEAKIVQVLNEELIKNHIESVVNTENFGLTHMLSNKKYSEIALMFNLLKRVDN------GLATMCSCISRFLREEGRKIVE----DDKTPQIYIQELIYXXXXXXXXXXXXXXXXQLFKNQINSDFEFFINQNSRSP-EYLSLYIDDKLKRGTKGISDQDIDAIFDKCIILFRYLQDKDIFERYYKQHLAKRLLMSKSQSDDQEKSMISKLLIECGGVFTSKLEGMFKDMAISKTLMEEFHSQLQMYTT-----NTLGIDLFVRVLTTGLWPTQTATQTVCMPD---EAQNAFSIY 1617
            FL  +   W ++   + +IR I++++DR + +      + ++  M ++RD  +    I + + V  L  +  +R G + S L L  A   +AQ+ +D L++Y+                 ESER L E ++  Y+  VN  +++E +R++ +L+  +   ++   L   ++K H++ ++ +   G  HM+ N     + L++NL + +++      G+  + +    ++ + G  IVE    D +  +   Q  + L+   + ++      +  F   I   FE F+N     P EYL+ ++D KL+ G K ++++ ++ I DK + LFR++  KD+FE +Y + LAKRLLM KS   D EK+M+ KL  ECG  +T K+E MF D+  S+ L ++F     +        N + I++ V V+    WP+   ++ + +P    + QNAFS +
Sbjct:   64 FLNHITTSWNEYCMKIEIIRSIMLFVDRKFWSNNSSLMSFWDMAMQLWRDMYITGPLINKEI-VLCLKQIHNQRDG-ISSDLSLSKA---VAQMFID-LDLYQS---------------QESERKLKELSNTDYLVYVNTRLDEENERSQMYLSGDSIRIQLRDQLVNIILKPHLDELLKS---GFNHMMENNDIFYLELLYNLAQLLNSKSADSSGIYILRNYFKEYVMKSGTLIVENPNDDVEKDKKMTQNFLDLKVHLDSVVEKCFKGDMSFYKTIRDCFEAFLNARPNKPAEYLAKFLDSKLRSGNKNLTEEAMELIMDKVMTLFRFITGKDVFEAFYLKDLAKRLLMGKSACVDTEKAMLEKLKHECGPNYTRKMEIMFSDIDNSQRLSKQFSDSNSLQNIIDKDMNKVNIEMNVNVICNATWPSLGGSKLLNIPQYMIDMQNAFSAF 492
The following BLAST results are available for this feature:
BLAST of Cullin 3 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
CUL30.000e+055.89cullin 3 [Source:HGNC Symbol;Acc:HGNC:2553][more]
CUL30.000e+055.97cullin 3 [Source:HGNC Symbol;Acc:HGNC:2553][more]
CUL30.000e+055.97cullin 3 [Source:HGNC Symbol;Acc:HGNC:2553][more]
CUL39.285e-16854.36cullin 3 [Source:HGNC Symbol;Acc:HGNC:2553][more]
CUL4A1.800e-8632.36cullin 4A [Source:HGNC Symbol;Acc:HGNC:2554][more]
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BLAST of Cullin 3 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
cul-34.278e-14342.86Cullin-3 [Source:UniProtKB/Swiss-Prot;Acc:Q17391][more]
cul-34.278e-14342.86Cullin-3 [Source:UniProtKB/Swiss-Prot;Acc:Q17391][more]
cul-34.278e-14342.86Cullin-3 [Source:UniProtKB/Swiss-Prot;Acc:Q17391][more]
cul-32.088e-11640.46Cullin-3 [Source:UniProtKB/Swiss-Prot;Acc:Q17391][more]
cul-13.348e-3924.40Cullin-1 [Source:UniProtKB/Swiss-Prot;Acc:Q17389][more]
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BLAST of Cullin 3 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Cul30.000e+051.69gene:FBgn0261268 transcript:FBtr0302158[more]
Cul30.000e+051.69gene:FBgn0261268 transcript:FBtr0302157[more]
Cul30.000e+051.69gene:FBgn0261268 transcript:FBtr0302156[more]
Cul31.209e-17851.83gene:FBgn0261268 transcript:FBtr0302159[more]
Cul43.640e-9033.95gene:FBgn0033260 transcript:FBtr0301355[more]
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BLAST of Cullin 3 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
cul3b0.000e+054.99cullin 3b [Source:ZFIN;Acc:ZDB-GENE-081007-1][more]
cul3a0.000e+055.75cullin 3a [Source:ZFIN;Acc:ZDB-GENE-030131-3376][more]
cul3b0.000e+054.99cullin 3b [Source:ZFIN;Acc:ZDB-GENE-081007-1][more]
cul4a1.152e-8832.46cullin 4A [Source:ZFIN;Acc:ZDB-GENE-040426-1357][more]
cul4b2.003e-8232.52cullin 4B [Source:ZFIN;Acc:ZDB-GENE-041008-208][more]
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BLAST of Cullin 3 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
cul30.000e+055.77cullin 3 [Source:NCBI gene;Acc:548729][more]
cul30.000e+055.86cullin 3 [Source:NCBI gene;Acc:548729][more]
cul30.000e+055.86cullin 3 [Source:NCBI gene;Acc:548729][more]
cul31.159e-16854.36cullin 3 [Source:NCBI gene;Acc:548729][more]
cul4a1.762e-8933.59cullin 4A [Source:NCBI gene;Acc:548647][more]
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BLAST of Cullin 3 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Cul30.000e+055.89cullin 3 [Source:MGI Symbol;Acc:MGI:1347360][more]
Cul34.133e-16854.36cullin 3 [Source:MGI Symbol;Acc:MGI:1347360][more]
Cul4a2.648e-8232.58cullin 4A [Source:MGI Symbol;Acc:MGI:1914487][more]
Cul4b2.766e-8132.53cullin 4B [Source:MGI Symbol;Acc:MGI:1919834][more]
Cul4b1.786e-8032.53cullin 4B [Source:MGI Symbol;Acc:MGI:1919834][more]
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BLAST of Cullin 3 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q6GPF3|CUL3B_XENLA0.000e+055.77Cullin-3-B OS=Xenopus laevis OX=8355 GN=cul3b PE=1... [more]
sp|A4IHP4|CUL3_XENTR0.000e+055.77Cullin-3 OS=Xenopus tropicalis OX=8364 GN=cul3 PE=... [more]
sp|Q6DE95|CUL3A_XENLA0.000e+055.77Cullin-3-A OS=Xenopus laevis OX=8355 GN=cul3a PE=1... [more]
sp|B5DF89|CUL3_RAT0.000e+055.89Cullin-3 OS=Rattus norvegicus OX=10116 GN=Cul3 PE=... [more]
sp|Q9JLV5|CUL3_MOUSE0.000e+055.89Cullin-3 OS=Mus musculus OX=10090 GN=Cul3 PE=1 SV=... [more]
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BLAST of Cullin 3 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A5J4NTB70.000e+063.25Cullin 3 OS=Paragonimus westermani OX=34504 GN=DEA... [more]
A0A2H1BV540.000e+063.25Cullin family protein OS=Fasciola hepatica OX=6192... [more]
A0A4S2MB970.000e+061.38CULLIN_2 domain-containing protein OS=Opisthorchis... [more]
A0A0X3PL620.000e+061.04Cullin-3 (Fragment) OS=Schistocephalus solidus OX=... [more]
A0A183SVC20.000e+061.04Cullin-3 OS=Schistocephalus solidus OX=70667 GN=SS... [more]
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BLAST of Cullin 3 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
cul3b0.000e+054.99cullin 3 [Source:NCBI gene;Acc:103024283][more]
cul3a0.000e+054.95cullin 3a [Source:ZFIN;Acc:ZDB-GENE-030131-3376][more]
cul4b3.841e-8033.08cullin 4B [Source:ZFIN;Acc:ZDB-GENE-041008-208][more]
cul4a7.730e-7333.57cullin 4A [Source:ZFIN;Acc:ZDB-GENE-040426-1357][more]
ENSAMXT00000057183.14.741e-6434.77pep primary_assembly:Astyanax_mexicanus-2.0:APWO02... [more]
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BLAST of Cullin 3 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5
Match NameE-valueIdentityDescription
cul4b1.811e-8332.33cullin 4B [Source:ZFIN;Acc:ZDB-GENE-041008-208][more]
cul1b8.180e-5425.71cullin 1b [Source:ZFIN;Acc:ZDB-GENE-040426-2887][more]
cul1b4.817e-5327.10cullin 1b [Source:ZFIN;Acc:ZDB-GENE-040426-2887][more]
cul26.550e-3926.53cullin 2 [Source:ZFIN;Acc:ZDB-GENE-030131-8032][more]
cul5a3.099e-1025.00cullin 5a [Source:ZFIN;Acc:ZDB-GENE-030131-5426][more]
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BLAST of Cullin 3 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 2
Match NameE-valueIdentityDescription
CDC531.696e-2822.98Cullin; structural protein of SCF complexes (which... [more]
CUL32.551e-2325.79Ubiquitin-protein ligase; forms a complex with Elc... [more]
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BLAST of Cullin 3 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO352302.591e-17052.95Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO356601.837e-6734.38Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO375702.833e-5525.62Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO490911.338e-4625.70Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO460743.529e-2929.39Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Cullin 3 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
CUL30.000e+055.36cullin-3-like [Source:NCBI gene;Acc:101170875][more]
cul3b0.000e+055.66cullin-3 [Source:NCBI gene;Acc:101172920][more]
CUL30.000e+055.08cullin-3-like [Source:NCBI gene;Acc:101170875][more]
cul4b3.459e-8232.95cullin 4B [Source:NCBI gene;Acc:101161413][more]
cul4a2.762e-7333.33cullin-4A [Source:NCBI gene;Acc:101154851][more]
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BLAST of Cullin 3 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000001134.10.000e+099.81SMESG000001134.1[more]
SMESG000033325.10.000e+065.74SMESG000033325.1[more]
SMESG000008644.11.038e-4224.80SMESG000008644.1[more]
SMESG000054773.12.321e-4127.38SMESG000054773.1[more]
SMESG000001104.11.201e-3826.49SMESG000001104.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30027794 ID=SMED30027794|Name=Cullin 3|organism=Schmidtea mediterranea sexual|type=transcript|length=1622bp
ATGCAACTTTACATTATGTCTGGAAATATTCGTAAATTAGATTCATCAGT
TTCTTCAAATCCATCTAAAATGAGAATTAAAGCTTTTCCAACATCAATGA
GTGATCAATCTGTTAGTAAAATATGGGAATGTTTGAAAAGGGCTATTATT
GAAATACAAAAGAAAAATAATAGTGGATTAAGTTTTGAAGAGCTTTATAG
AAATGCTTATACGATGGTTTTACAGAAAAACGGTGAGCAGTTATATAATG
GTACTAAAGCAGTTGTCACAGATCACATGATCAAAATACGAGACGAAGTT
TTGGAAAGATTAACCAATAATTTTTTAGCTTTCCTGAACCGGTGTTGGAA
AGATCATATAACTGCTATGGTCATGATCAGAGATATTTTAATGTATATGG
ATAGGGTATATGTTACCACAACTGATAAACCAAATGTATATAATACAGGA
ATGATAATTTTTAGAGATACAGTATTGCGCCACGAAGCCATACGTCGTCA
TTTAAGAGTAACTTTATTAGATATGGTCAAAAGAGAACGTCATGGAGAGG
TGATATCACGTTTACAATTACGTGACGCTTGTCAGATGTTAGCGCAATTG
GGCGTAGATAAGTTAAACATTTATGAAGAAGATTTTGAAAACTATTTTCT
TGAACAATCACGAGATTTTTATCGATCTGAAAGTGAGCGATTATTGACGG
AAAATGCCTCAAATTTGTACATAACTCAAGTAAATAAAATAATCGAAGAT
GAGGCAAAACGAGCTAGGGATTTTTTAAATTCAACAACCGAAGCGAAAAT
TGTACAGGTTTTAAATGAAGAATTGATCAAAAATCATATCGAATCGGTTG
TAAATACAGAGAATTTTGGTTTGACTCACATGTTGAGCAATAAAAAATAT
TCTGAAATCGCTTTGATGTTCAATCTGTTGAAACGAGTCGACAACGGATT
GGCGACAATGTGCAGTTGCATCAGTAGGTTTTTGCGGGAAGAAGGACGGA
AAATTGTCGAAGATGACAAAACTCCTCAAATTTACATTCAAGAATTGATC
TATCTGCGAGATCGTGCCAATGATTTATTATTGAACGCTTTGCTAAATAA
TCAGCTTTTCAAAAATCAAATAAATTCTGATTTCGAGTTCTTCATCAATC
AGAATTCTCGCTCACCGGAATATTTATCTCTTTATATCGATGATAAATTG
AAACGCGGCACCAAAGGAATTAGCGATCAAGACATTGATGCCATTTTCGA
TAAATGCATCATTCTGTTTCGATATTTACAAGACAAAGATATTTTTGAGA
GGTATTACAAGCAACATTTGGCGAAACGATTGTTGATGAGTAAGAGTCAA
TCAGATGATCAAGAAAAGAGCATGATATCGAAATTGCTAATCGAATGCGG
TGGAGTTTTCACTAGCAAATTAGAAGGAATGTTCAAAGATATGGCTATAT
CGAAAACGTTAATGGAGGAATTTCATTCTCAACTGCAAATGTATACAACC
AATACTTTGGGAATCGATTTATTTGTTCGGGTCCTCACAACCGGGTTGTG
GCCGACACAGACAGCTACCCAAACCGTTTGCATGCCAGATGAAGCTCAGA
ATGCATTTAGTATCTATTCAAG
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protein sequence of SMED30027794-orf-1

>SMED30027794-orf-1 ID=SMED30027794-orf-1|Name=SMED30027794-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=540bp
MQLYIMSGNIRKLDSSVSSNPSKMRIKAFPTSMSDQSVSKIWECLKRAII
EIQKKNNSGLSFEELYRNAYTMVLQKNGEQLYNGTKAVVTDHMIKIRDEV
LERLTNNFLAFLNRCWKDHITAMVMIRDILMYMDRVYVTTTDKPNVYNTG
MIIFRDTVLRHEAIRRHLRVTLLDMVKRERHGEVISRLQLRDACQMLAQL
GVDKLNIYEEDFENYFLEQSRDFYRSESERLLTENASNLYITQVNKIIED
EAKRARDFLNSTTEAKIVQVLNEELIKNHIESVVNTENFGLTHMLSNKKY
SEIALMFNLLKRVDNGLATMCSCISRFLREEGRKIVEDDKTPQIYIQELI
YLRDRANDLLLNALLNNQLFKNQINSDFEFFINQNSRSPEYLSLYIDDKL
KRGTKGISDQDIDAIFDKCIILFRYLQDKDIFERYYKQHLAKRLLMSKSQ
SDDQEKSMISKLLIECGGVFTSKLEGMFKDMAISKTLMEEFHSQLQMYTT
NTLGIDLFVRVLTTGLWPTQTATQTVCMPDEAQNAFSIYS
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: INTERPRO
TermDefinition
IPR036317Cullin_homology_sf
IPR016158Cullin_homology
IPR001373Cullin_N
IPR016159Cullin_repeat-like_dom_sf
Vocabulary: biological process
TermDefinition
GO:0006511ubiquitin-dependent protein catabolic process
Vocabulary: molecular function
TermDefinition
GO:0031625ubiquitin protein ligase binding
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR016158Cullin homology domainSMARTSM00182cul_2coord: 412..535
e-value: 4.8E-36
score: 135.7
IPR016158Cullin homology domainPROSITEPS50069CULLIN_2coord: 382..535
score: 37.198
NoneNo IPR availableGENE3DG3DSA:1.20.1310.10coord: 276..380
e-value: 1.9E-22
score: 81.4
NoneNo IPR availableGENE3DG3DSA:1.20.1310.10coord: 22..151
e-value: 4.4E-42
score: 145.7
NoneNo IPR availableGENE3DG3DSA:1.20.1310.10coord: 153..275
e-value: 4.3E-35
score: 122.1
NoneNo IPR availableGENE3DG3DSA:1.20.1310.10coord: 381..494
e-value: 2.4E-41
score: 142.5
NoneNo IPR availablePANTHERPTHR11932:SF126CULLIN-3coord: 32..532
NoneNo IPR availablePANTHERPTHR11932CULLINcoord: 32..532
IPR001373Cullin, N-terminalPFAMPF00888Cullincoord: 37..532
e-value: 1.4E-157
score: 526.0
IPR036317Cullin homology domain superfamilySUPERFAMILYSSF75632Cullin homology domaincoord: 376..534
IPR016159Cullin repeat-like-containing domain superfamilySUPERFAMILYSSF74788Cullin repeat-likecoord: 30..380