high mobility group-2

Overview


Name	high mobility group-2 (AFJ24755.1)
Smed ID	SMED30027770
Length (bp)	686

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of high mobility group-2 (SMED30027770) t-SNE clustered cells

Violin plots show distribution of expression levels for high mobility group-2 (SMED30027770) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of high mobility group-2 (SMED30027770) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for high mobility group-2 (SMED30027770) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30027770

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 17

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication
X1 cell	SMED30027770	SMESG000020771.1	SmedASXL_006537	SmedAsxl_ww_GCZZ01	PMID:26114597 Zhu et al., 2015
nervous system	SMED30027770	SMESG000020771.1	dd_Smed_v4_1646_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
epidermis	SMED30027770	SMESG000020771.1	dd_Smed_v4_1646_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
cephalic ganglia	SMED30027770	SMESG000020771.1	dd_Smed_v4_1646_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
neuron	SMED30027770	SMESG000020771.1	dd_Smed_v4_1646_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
neoblast	SMED30027770	SMESG000020771.1	dd_Smed_v4_1646_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
parenchymal cell	SMED30027770	SMESG000020771.1	dd_Smed_v4_1646_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
muscle cell	SMED30027770	SMESG000020771.1	dd_Smed_v4_1646_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30027770	SMESG000020771.1	Contig50327	newmark_ests	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30027770	SMESG000020771.1	Contig50327	uc_Smed_v2	PMID:29674431 Fincher et al., 2018
X1 cell	SMED30027770	SMESG000020771.1	CUFF.40159.1	be_Smed_v2	PMID:22543868 Onal et al., 2012
zeta neoblast	SMED30027770	SMESG000020771.1	dd_Smed_v4_1646_0_1	dd_Smed_v4	PMID:28292427 Wurtzel et al., 2017
Category 1 cell	SMED30027770	SMESG000020771.1	H.22.5f	smed_ncbi_20200123	PMID:18786419 Eisenhoffer et al., 2008
Category 1 cell	SMED30027770	SMESG000020771.1	H.22.5f	smed_ncbi_20200123	PMID:18786419 Eisenhoffer et al., 2008
neoblast	SMED30027770	SMESG000020771.1	SMED30027770	smed_20140614	PMID:27523733 Lei et al., 2016
neoblast	SMED30027770	SMESG000020771.1	SMED_09062_V2_1	GPL14150_gene_models	PMID:22385657 Wagner et al., 2012
neoblast	SMED30027770	SMESG000020771.1	SMED_09062_V2_1	GPL14150	PMID:22385657 Wagner et al., 2012

Note: Hover over icons to view figure legend

Homology

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BLAST of high mobility group-2 vs. Ensembl Human
Match: HMGB1 (high mobility group box 1 [Source:HGNC Symbol;Acc:HGNC:4983])

HSP 1 Score: 130.568 bits (327), Expect = 8.162e-38
Identity = 65/134 (48.51%), Postives = 90/134 (67.16%), Query Frame = 1

Query:   43 KKPSGAKSAYIIYTQAVREEYKKKNPDGKVNFTEISKIASEKWKNISDKEKEKYNVLAQADKKRYTKEMEGYEPETDNRKPSKKAKREAKDPNKPKAPLTAFFFFSNEHRQTVKEKNPEFKVGDIAKVLGKMWS 444
            KKP G  S+Y  + Q  REE+KKK+PD  VNF+E SK  SE+WK +S KEK K+  +A+ADK RY +EM+ Y P      P  + K++ KDPN PK P +AFF F +E+R  +K ++P   +GD+AK LG+MW+
Sbjct:    7 KKPRGKMSSYAFFVQTCREEHKKKHPDASVNFSEFSKKCSERWKTMSAKEKGKFEDMAKADKARYEREMKTYIP------PKGETKKKFKDPNAPKRPPSAFFLFCSEYRPKIKGEHPGLSIGDVAKKLGEMWN 134

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Query:   43 KKPSGAKSAYIIYTQAVREEYKKKNPDGKVNFTEISKIASEKWKNISDKEKEKYNVLAQADKKRYTKEMEGYEPETDNRKPSKKAKREAKDPNKPKAPLTAFFFFSNEHRQTVKEKNPEFKVGDIAKVLGKMWS 444
            KKP G  S+Y  + Q  REE+KKK+PD  VNF+E SK  SE+WK +S KEK K+  +A+ADK RY +EM+ Y P      P  + K++ KDPN PK P +AFF F +E+R  +K ++P   +GD+AK LG+MW+
Sbjct:    7 KKPRGKMSSYAFFVQTCREEHKKKHPDASVNFSEFSKKCSERWKTMSAKEKGKFEDMAKADKARYEREMKTYIP------PKGETKKKFKDPNAPKRPPSAFFLFCSEYRPKIKGEHPGLSIGDVAKKLGEMWN 134

[Close]

BLAST of high mobility group-2 vs. Ensembl Human
Match: HMGB1 (high mobility group box 1 [Source:HGNC Symbol;Acc:HGNC:4983])

HSP 1 Score: 132.109 bits (331), Expect = 1.236e-37
Identity = 78/174 (44.83%), Postives = 108/174 (62.07%), Query Frame = 1

Query:   37 NNKKPSGAKSAYIIYTQAVREEYKKKNPDGKVNFTEISKIASEKWKNISDKEKEKYNVLAQADKKRYTKEMEGYEPETDNRKPSKKAKREAKDPNKPKAPLTAFFFFSNEHRQTVKEKNPEFKVGDIAKVLGKMW--SECKDKSKYEEMNKEAKEKYNLAMLEYK-NGVPSAKK 549
            + KKP G  S+Y  + Q  REE+KKK+PD  VNF+E SK  SE+WK +S KEK K+  +A+ADK RY +EM+ Y P      P  + K++ KDPN PK P +AFF F +E+R  +K ++P   +GD+AK LG+MW  +   DK  YE+   + KEKY   +  Y+  G P A K
Sbjct:    5 DPKKPRGKMSSYAFFVQTCREEHKKKHPDASVNFSEFSKKCSERWKTMSAKEKGKFEDMAKADKARYEREMKTYIP------PKGETKKKFKDPNAPKRPPSAFFLFCSEYRPKIKGEHPGLSIGDVAKKLGEMWNNTAADDKQPYEKKAAKLKEKYEKDIAAYRAKGKPDAAK 172

[Close]

Query:   37 NNKKPSGAKSAYIIYTQAVREEYKKKNPDGKVNFTEISKIASEKWKNISDKEKEKYNVLAQADKKRYTKEMEGYEPETDNRKPSKKAKREAKDPNKPKAPLTAFFFFSNEHRQTVKEKNPEFKVGDIAKVLGKMW--SECKDKSKYEEMNKEAKEKYNLAMLEYK-NGVPSAKK 549
            + KKP G  S+Y  + Q  REE+KKK+PD  VNF+E SK  SE+WK +S KEK K+  +A+ADK RY +EM+ Y P      P  + K++ KDPN PK P +AFF F +E+R  +K ++P   +GD+AK LG+MW  +   DK  YE+   + KEKY   +  Y+  G P A K
Sbjct:    5 DPKKPRGKMSSYAFFVQTCREEHKKKHPDASVNFSEFSKKCSERWKTMSAKEKGKFEDMAKADKARYEREMKTYIP------PKGETKKKFKDPNAPKRPPSAFFLFCSEYRPKIKGEHPGLSIGDVAKKLGEMWNNTAADDKQPYEKKAAKLKEKYEKDIAAYRAKGKPDAAK 172

[Close]

Query:   37 NNKKPSGAKSAYIIYTQAVREEYKKKNPDGKVNFTEISKIASEKWKNISDKEKEKYNVLAQADKKRYTKEMEGYEPETDNRKPSKKAKREAKDPNKPKAPLTAFFFFSNEHRQTVKEKNPEFKVGDIAKVLGKMW--SECKDKSKYEEMNKEAKEKYNLAMLEYK-NGVPSAKK 549
            + KKP G  S+Y  + Q  REE+KKK+PD  VNF+E SK  SE+WK +S KEK K+  +A+ADK RY +EM+ Y P      P  + K++ KDPN PK P +AFF F +E+R  +K ++P   +GD+AK LG+MW  +   DK  YE+   + KEKY   +  Y+  G P A K
Sbjct:    5 DPKKPRGKMSSYAFFVQTCREEHKKKHPDASVNFSEFSKKCSERWKTMSAKEKGKFEDMAKADKARYEREMKTYIP------PKGETKKKFKDPNAPKRPPSAFFLFCSEYRPKIKGEHPGLSIGDVAKKLGEMWNNTAADDKQPYEKKAAKLKEKYEKDIAAYRAKGKPDAAK 172

[Close]

BLAST of high mobility group-2 vs. Ensembl Celegans
Match: hmg-1.2 (High mobility group protein 1.2 [Source:UniProtKB/Swiss-Prot;Acc:Q09390])

HSP 1 Score: 112.849 bits (281), Expect = 1.586e-30
Identity = 68/173 (39.31%), Postives = 95/173 (54.91%), Query Frame = 1

Query:   13 YNLVTKSMNNKKPSGAKSAYIIYTQAVREEYKKKNPDGKVNFTEISKIASEKWKNISDKEKEKYNVLAQADKKRYTKEMEGYEPETDNRKPSKKAKREAKDPNKPKAPLTAFFFFSNEHRQTVKEKNPEFKVGDIAKVLGKMWSECKDKSK--YEEMNKEAKEKYNLAMLEYK 525
            Y    + M      G  S Y  + +   EE+KKK P+  V  TEISK  SEKWK + D EK ++  LAQ D +RY  E+  Y  E   R    K KR  KDP+ PK  L+AFFF+S + R  ++  +P++KVG +A+ LGKMW     ++K  YE+  +  K++Y   M  YK
Sbjct:   33 YQATPRDMGKPPVRGKTSPYGFFVKMCYEEHKKKYPNENVQVTEISKKCSEKWKTMVDDEKRRFYELAQKDAERYQAEVAAYGGEDAMR----KRKRAKKDPHAPKRALSAFFFYSQDKRPEIQAGHPDWKVGQVAQELGKMWKLVPQETKDMYEQKAQADKDRYADEMRNYK 201

HSP 2 Score: 46.595 bits (109), Expect = 4.007e-6
Identity = 27/73 (36.99%), Postives = 40/73 (54.79%), Query Frame = 1

Query:   49 PSGAKSAYIIYTQAVREEYKKKNPDGKVNFTEISKIASEKWKNISDKEKEKYNVLAQADKKRYTKEMEGYEPE 267
            P  A SA+  Y+Q  R E +  +PD KV   ++++   + WK +  + K+ Y   AQADK RY  EM  Y+ E
Sbjct:  133 PKRALSAFFFYSQDKRPEIQAGHPDWKVG--QVAQELGKMWKLVPQETKDMYEQKAQADKDRYADEMRNYKAE 203

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Query:   13 YNLVTKSMNNKKPSGAKSAYIIYTQAVREEYKKKNPDGKVNFTEISKIASEKWKNISDKEKEKYNVLAQADKKRYTKEMEGYEPETDNRKPSKKAKREAKDPNKPKAPLTAFFFFSNEHRQTVKEKNPEFKVGDIAKVLGKMWSECKDKSK--YEEMNKEAKEKYNLAMLEYK 525
            Y    + M      G  S Y  + +   EE+KKK P+  V  TEISK  SEKWK + D EK ++  LAQ D +RY  E+  Y  E   R    K KR  KDP+ PK  L+AFFF+S + R  ++  +P++KVG +A+ LGKMW     ++K  YE+  +  K++Y   M  YK
Sbjct:   33 YQATPRDMGKPPVRGKTSPYGFFVKMCYEEHKKKYPNENVQVTEISKKCSEKWKTMVDDEKRRFYELAQKDAERYQAEVAAYGGEDAMR----KRKRAKKDPHAPKRALSAFFFYSQDKRPEIQAGHPDWKVGQVAQELGKMWKLVPQETKDMYEQKAQADKDRYADEMRNYK 201

HSP 2 Score: 46.595 bits (109), Expect = 4.007e-6
Identity = 27/73 (36.99%), Postives = 40/73 (54.79%), Query Frame = 1

Query:   49 PSGAKSAYIIYTQAVREEYKKKNPDGKVNFTEISKIASEKWKNISDKEKEKYNVLAQADKKRYTKEMEGYEPE 267
            P  A SA+  Y+Q  R E +  +PD KV   ++++   + WK +  + K+ Y   AQADK RY  EM  Y+ E
Sbjct:  133 PKRALSAFFFYSQDKRPEIQAGHPDWKVG--QVAQELGKMWKLVPQETKDMYEQKAQADKDRYADEMRNYKAE 203

[Close]

BLAST of high mobility group-2 vs. Ensembl Celegans
Match: hmg-1.2 (High mobility group protein 1.2 [Source:UniProtKB/Swiss-Prot;Acc:Q09390])

HSP 1 Score: 108.227 bits (269), Expect = 9.780e-29
Identity = 68/175 (38.86%), Postives = 95/175 (54.29%), Query Frame = 1

Query:   13 YNLVTKSMNNKKPSGAKSAYIIYTQAVREEYKKKNPDGKVNFTEISKIASEKWKNISDKEKEKYNVLAQADKKRYTKEME--GYEPETDNRKPSKKAKREAKDPNKPKAPLTAFFFFSNEHRQTVKEKNPEFKVGDIAKVLGKMWSECKDKSK--YEEMNKEAKEKYNLAMLEYK 525
            Y    + M      G  S Y  + +   EE+KKK P+  V  TEISK  SEKWK + D EK ++  LAQ D +RY  E+    Y  E   R    K KR  KDP+ PK  L+AFFF+S + R  ++  +P++KVG +A+ LGKMW     ++K  YE+  +  K++Y   M  YK
Sbjct:   32 YQATPRDMGKPPVRGKTSPYGFFVKMCYEEHKKKYPNENVQVTEISKKCSEKWKTMVDDEKRRFYELAQKDAERYQAEVSVAAYGGEDAMR----KRKRAKKDPHAPKRALSAFFFYSQDKRPEIQAGHPDWKVGQVAQELGKMWKLVPQETKDMYEQKAQADKDRYADEMRNYK 202

HSP 2 Score: 46.595 bits (109), Expect = 4.069e-6
Identity = 27/73 (36.99%), Postives = 40/73 (54.79%), Query Frame = 1

Query:   49 PSGAKSAYIIYTQAVREEYKKKNPDGKVNFTEISKIASEKWKNISDKEKEKYNVLAQADKKRYTKEMEGYEPE 267
            P  A SA+  Y+Q  R E +  +PD KV   ++++   + WK +  + K+ Y   AQADK RY  EM  Y+ E
Sbjct:  134 PKRALSAFFFYSQDKRPEIQAGHPDWKVG--QVAQELGKMWKLVPQETKDMYEQKAQADKDRYADEMRNYKAE 204

[Close]

BLAST of high mobility group-2 vs. Ensembl Celegans
Match: hmg-1.2 (High mobility group protein 1.2 [Source:UniProtKB/Swiss-Prot;Acc:Q09390])

HSP 1 Score: 108.227 bits (269), Expect = 1.055e-28
Identity = 68/175 (38.86%), Postives = 95/175 (54.29%), Query Frame = 1

Query:   13 YNLVTKSMNNKKPSGAKSAYIIYTQAVREEYKKKNPDGKVNFTEISKIASEKWKNISDKEKEKYNVLAQADKKRYTKEME--GYEPETDNRKPSKKAKREAKDPNKPKAPLTAFFFFSNEHRQTVKEKNPEFKVGDIAKVLGKMWSECKDKSK--YEEMNKEAKEKYNLAMLEYK 525
            Y    + M      G  S Y  + +   EE+KKK P+  V  TEISK  SEKWK + D EK ++  LAQ D +RY  E+    Y  E   R    K KR  KDP+ PK  L+AFFF+S + R  ++  +P++KVG +A+ LGKMW     ++K  YE+  +  K++Y   M  YK
Sbjct:   33 YQATPRDMGKPPVRGKTSPYGFFVKMCYEEHKKKYPNENVQVTEISKKCSEKWKTMVDDEKRRFYELAQKDAERYQAEVSVAAYGGEDAMR----KRKRAKKDPHAPKRALSAFFFYSQDKRPEIQAGHPDWKVGQVAQELGKMWKLVPQETKDMYEQKAQADKDRYADEMRNYK 203

HSP 2 Score: 46.595 bits (109), Expect = 4.171e-6
Identity = 27/73 (36.99%), Postives = 40/73 (54.79%), Query Frame = 1

Query:   49 PSGAKSAYIIYTQAVREEYKKKNPDGKVNFTEISKIASEKWKNISDKEKEKYNVLAQADKKRYTKEMEGYEPE 267
            P  A SA+  Y+Q  R E +  +PD KV   ++++   + WK +  + K+ Y   AQADK RY  EM  Y+ E
Sbjct:  135 PKRALSAFFFYSQDKRPEIQAGHPDWKVG--QVAQELGKMWKLVPQETKDMYEQKAQADKDRYADEMRNYKAE 205

[Close]

BLAST of high mobility group-2 vs. Ensembl Celegans
Match: hmg-1.2 (High mobility group protein 1.2 [Source:UniProtKB/Swiss-Prot;Acc:Q09390])

HSP 1 Score: 108.227 bits (269), Expect = 1.055e-28
Identity = 68/175 (38.86%), Postives = 95/175 (54.29%), Query Frame = 1

Query:   13 YNLVTKSMNNKKPSGAKSAYIIYTQAVREEYKKKNPDGKVNFTEISKIASEKWKNISDKEKEKYNVLAQADKKRYTKEME--GYEPETDNRKPSKKAKREAKDPNKPKAPLTAFFFFSNEHRQTVKEKNPEFKVGDIAKVLGKMWSECKDKSK--YEEMNKEAKEKYNLAMLEYK 525
            Y    + M      G  S Y  + +   EE+KKK P+  V  TEISK  SEKWK + D EK ++  LAQ D +RY  E+    Y  E   R    K KR  KDP+ PK  L+AFFF+S + R  ++  +P++KVG +A+ LGKMW     ++K  YE+  +  K++Y   M  YK
Sbjct:   33 YQATPRDMGKPPVRGKTSPYGFFVKMCYEEHKKKYPNENVQVTEISKKCSEKWKTMVDDEKRRFYELAQKDAERYQAEVSVAAYGGEDAMR----KRKRAKKDPHAPKRALSAFFFYSQDKRPEIQAGHPDWKVGQVAQELGKMWKLVPQETKDMYEQKAQADKDRYADEMRNYK 203

HSP 2 Score: 46.595 bits (109), Expect = 4.171e-6
Identity = 27/73 (36.99%), Postives = 40/73 (54.79%), Query Frame = 1

Query:   49 PSGAKSAYIIYTQAVREEYKKKNPDGKVNFTEISKIASEKWKNISDKEKEKYNVLAQADKKRYTKEMEGYEPE 267
            P  A SA+  Y+Q  R E +  +PD KV   ++++   + WK +  + K+ Y   AQADK RY  EM  Y+ E
Sbjct:  135 PKRALSAFFFYSQDKRPEIQAGHPDWKVG--QVAQELGKMWKLVPQETKDMYEQKAQADKDRYADEMRNYKAE 205

[Close]

BLAST of high mobility group-2 vs. Ensembl Fly
Match: Dsp1 (gene:FBgn0278608 transcript:FBtr0089259)

HSP 1 Score: 141.739 bits (356), Expect = 5.565e-40
Identity = 75/165 (45.45%), Postives = 103/165 (62.42%), Query Frame = 1

Query:   40 NKKPSGAKSAYIIYTQAVREEYKKKNPDGKVNFTEISKIASEKWKNISDKEKEKYNVLAQADKKRYTKEMEGYEPETDNRKPSKKAKREAKDPNKPKAPLTAFFFFSNEHRQTVKEKNPEFKVGDIAKVLGKMWSEC--KDKSKYEEMNKEAKEKYNLAMLEYKN 528
            + KP G  +AY  + Q  REE+KKK+PD  V F E S+  +E+WK + DKEK++++ +A+ DK+RY  EM+ Y P         K +++ KDPN PK  L+AFF+F N+ R  VK  NPEF VGDIAK LG+ WS+   + K KYE M +  K +Y   M EYK 
Sbjct:  168 DAKPRGRMTAYAYFVQTCREEHKKKHPDETVIFAEFSRKCAERWKTMVDKEKKRFHEMAEKDKQRYEAEMQNYVPPKGAVVGRGKKRKQIKDPNAPKRSLSAFFWFCNDERNKVKALNPEFGVGDIAKELGRKWSDVDPEVKQKYESMAERDKARYEREMTEYKT 332

[Close]

BLAST of high mobility group-2 vs. Ensembl Fly
Match: Dsp1 (gene:FBgn0278608 transcript:FBtr0089260)

HSP 1 Score: 141.739 bits (356), Expect = 5.565e-40
Identity = 75/165 (45.45%), Postives = 103/165 (62.42%), Query Frame = 1

Query:   40 NKKPSGAKSAYIIYTQAVREEYKKKNPDGKVNFTEISKIASEKWKNISDKEKEKYNVLAQADKKRYTKEMEGYEPETDNRKPSKKAKREAKDPNKPKAPLTAFFFFSNEHRQTVKEKNPEFKVGDIAKVLGKMWSEC--KDKSKYEEMNKEAKEKYNLAMLEYKN 528
            + KP G  +AY  + Q  REE+KKK+PD  V F E S+  +E+WK + DKEK++++ +A+ DK+RY  EM+ Y P         K +++ KDPN PK  L+AFF+F N+ R  VK  NPEF VGDIAK LG+ WS+   + K KYE M +  K +Y   M EYK 
Sbjct:  168 DAKPRGRMTAYAYFVQTCREEHKKKHPDETVIFAEFSRKCAERWKTMVDKEKKRFHEMAEKDKQRYEAEMQNYVPPKGAVVGRGKKRKQIKDPNAPKRSLSAFFWFCNDERNKVKALNPEFGVGDIAKELGRKWSDVDPEVKQKYESMAERDKARYEREMTEYKT 332

[Close]

BLAST of high mobility group-2 vs. Ensembl Fly
Match: Dsp1 (gene:FBgn0278608 transcript:FBtr0089261)

HSP 1 Score: 141.739 bits (356), Expect = 5.565e-40
Identity = 75/165 (45.45%), Postives = 103/165 (62.42%), Query Frame = 1

Query:   40 NKKPSGAKSAYIIYTQAVREEYKKKNPDGKVNFTEISKIASEKWKNISDKEKEKYNVLAQADKKRYTKEMEGYEPETDNRKPSKKAKREAKDPNKPKAPLTAFFFFSNEHRQTVKEKNPEFKVGDIAKVLGKMWSEC--KDKSKYEEMNKEAKEKYNLAMLEYKN 528
            + KP G  +AY  + Q  REE+KKK+PD  V F E S+  +E+WK + DKEK++++ +A+ DK+RY  EM+ Y P         K +++ KDPN PK  L+AFF+F N+ R  VK  NPEF VGDIAK LG+ WS+   + K KYE M +  K +Y   M EYK 
Sbjct:  168 DAKPRGRMTAYAYFVQTCREEHKKKHPDETVIFAEFSRKCAERWKTMVDKEKKRFHEMAEKDKQRYEAEMQNYVPPKGAVVGRGKKRKQIKDPNAPKRSLSAFFWFCNDERNKVKALNPEFGVGDIAKELGRKWSDVDPEVKQKYESMAERDKARYEREMTEYKT 332

[Close]

BLAST of high mobility group-2 vs. Ensembl Fly
Match: Dsp1 (gene:FBgn0278608 transcript:FBtr0089262)

HSP 1 Score: 141.739 bits (356), Expect = 5.672e-40
Identity = 75/165 (45.45%), Postives = 103/165 (62.42%), Query Frame = 1

Query:   40 NKKPSGAKSAYIIYTQAVREEYKKKNPDGKVNFTEISKIASEKWKNISDKEKEKYNVLAQADKKRYTKEMEGYEPETDNRKPSKKAKREAKDPNKPKAPLTAFFFFSNEHRQTVKEKNPEFKVGDIAKVLGKMWSEC--KDKSKYEEMNKEAKEKYNLAMLEYKN 528
            + KP G  +AY  + Q  REE+KKK+PD  V F E S+  +E+WK + DKEK++++ +A+ DK+RY  EM+ Y P         K +++ KDPN PK  L+AFF+F N+ R  VK  NPEF VGDIAK LG+ WS+   + K KYE M +  K +Y   M EYK 
Sbjct:  169 DAKPRGRMTAYAYFVQTCREEHKKKHPDETVIFAEFSRKCAERWKTMVDKEKKRFHEMAEKDKQRYEAEMQNYVPPKGAVVGRGKKRKQIKDPNAPKRSLSAFFWFCNDERNKVKALNPEFGVGDIAKELGRKWSDVDPEVKQKYESMAERDKARYEREMTEYKT 333

[Close]

BLAST of high mobility group-2 vs. Ensembl Fly
Match: Dsp1 (gene:FBgn0278608 transcript:FBtr0339766)

HSP 1 Score: 141.739 bits (356), Expect = 5.672e-40
Identity = 75/165 (45.45%), Postives = 103/165 (62.42%), Query Frame = 1

Query:   40 NKKPSGAKSAYIIYTQAVREEYKKKNPDGKVNFTEISKIASEKWKNISDKEKEKYNVLAQADKKRYTKEMEGYEPETDNRKPSKKAKREAKDPNKPKAPLTAFFFFSNEHRQTVKEKNPEFKVGDIAKVLGKMWSEC--KDKSKYEEMNKEAKEKYNLAMLEYKN 528
            + KP G  +AY  + Q  REE+KKK+PD  V F E S+  +E+WK + DKEK++++ +A+ DK+RY  EM+ Y P         K +++ KDPN PK  L+AFF+F N+ R  VK  NPEF VGDIAK LG+ WS+   + K KYE M +  K +Y   M EYK 
Sbjct:  169 DAKPRGRMTAYAYFVQTCREEHKKKHPDETVIFAEFSRKCAERWKTMVDKEKKRFHEMAEKDKQRYEAEMQNYVPPKGAVVGRGKKRKQIKDPNAPKRSLSAFFWFCNDERNKVKALNPEFGVGDIAKELGRKWSDVDPEVKQKYESMAERDKARYEREMTEYKT 333

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BLAST of high mobility group-2 vs. Ensembl Zebrafish
Match: hmgb2a (high mobility group box 2a [Source:ZFIN;Acc:ZDB-GENE-051120-126])

HSP 1 Score: 135.961 bits (341), Expect = 2.113e-39
Identity = 79/172 (45.93%), Postives = 104/172 (60.47%), Query Frame = 1

Query:   46 KPSGAKSAYIIYTQAVREEYKKKNPDGKVNFTEISKIASEKWKNISDKEKEKYNVLAQADKKRYTKEMEGYEPETDNRKPSKKAKREAKDPNKPKAPLTAFFFFSNEHRQTVKEKNPEFKVGDIAKVLGKMWSEC--KDKSKYEEMNKEAKEKY--NLAMLEYKNGVPSAKK 549
            KP G  S+Y  + Q  REE+KKKNP   VNF+E SK  SE+W+ +S KEK K+  +A+ DK RY +EM+ Y P         K  ++ KDPN PK P +AFF F ++HR  VK  NP   +GDIAK LG+MWS+   K+KS YE+   + KEKY  ++A    K G P   K
Sbjct:    7 KPRGKTSSYAFFVQTCREEHKKKNPGTSVNFSEFSKKCSERWRTMSSKEKGKFEEMAKTDKVRYDREMKNYVPPK-----GAKGGKKKKDPNAPKRPPSAFFVFCSDHRPKVKGDNPGISIGDIAKKLGEMWSKLSPKEKSPYEQKAMKLKEKYEKDVAAYRAKGGKPDGAK 173

[Close]

BLAST of high mobility group-2 vs. Ensembl Zebrafish
Match: hmgb2b (high mobility group box 2b [Source:ZFIN;Acc:ZDB-GENE-040912-122])

HSP 1 Score: 134.806 bits (338), Expect = 6.444e-39
Identity = 72/171 (42.11%), Postives = 109/171 (63.74%), Query Frame = 1

Query:   46 KPSGAKSAYIIYTQAVREEYKKKNPDGKVNFTEISKIASEKWKNISDKEKEKYNVLAQADKKRYTKEMEGYEPETDNRKPSKKAKREAKDPNKPKAPLTAFFFFSNEHRQTVKEKNPEFKVGDIAKVLGKMWS--ECKDKSKYEEMNKEAKEKYNLAMLEYKNGVPSAKKS 552
            KP G  SAY  + Q  R+E+K+K+PD  VNF+E SK  SE+WK+++  +K K+  +A+ADK RY +EM+ Y P     K   K  R+ KDPN PK P +AFF F +E+R TVK ++P   +G+IAK LG++WS    KD++ +E+   + +EKY   +  Y+ G  ++K+ 
Sbjct:    8 KPKGKTSAYAFFVQTCRDEHKRKSPDVPVNFSEFSKKCSERWKSLNASDKVKFEDMAKADKVRYDREMKTYVPP----KGVGKTGRKKKDPNAPKRPPSAFFVFCSEYRPTVKSEHPNLTIGEIAKKLGELWSKQSSKDRAPFEQKAGKLREKYEKEVAAYRAGGGASKRG 174

[Close]

Query:   46 KPSGAKSAYIIYTQAVREEYKKKNPDGKVNFTEISKIASEKWKNISDKEKEKYNVLAQADKKRYTKEMEGYEPETDNRKPSKKAKREAKDPNKPKAPLTAFFFFSNEHRQTVKEKNPEFKVGDIAKVLGKMWS--ECKDKSKYEEMNKEAKEKYNLAMLEYKNGVPSAKKS 552
            KP G  SAY  + Q  R+E+K+K+PD  VNF+E SK  SE+WK+++  +K K+  +A+ADK RY +EM+ Y P     K   K  R+ KDPN PK P +AFF F +E+R TVK ++P   +G+IAK LG++WS    KD++ +E+   + +EKY   +  Y+ G  ++K+ 
Sbjct:    8 KPKGKTSAYAFFVQTCRDEHKRKSPDVPVNFSEFSKKCSERWKSLNASDKVKFEDMAKADKVRYDREMKTYVPP----KGVGKTGRKKKDPNAPKRPPSAFFVFCSEYRPTVKSEHPNLTIGEIAKKLGELWSKQSSKDRAPFEQKAGKLREKYEKEVAAYRAGGGASKRG 174

[Close]

BLAST of high mobility group-2 vs. Ensembl Zebrafish
Match: hmgb2a (high mobility group box 2a [Source:ZFIN;Acc:ZDB-GENE-051120-126])

HSP 1 Score: 133.265 bits (334), Expect = 8.290e-39
Identity = 74/154 (48.05%), Postives = 97/154 (62.99%), Query Frame = 1

Query:   46 KPSGAKSAYIIYTQAVREEYKKKNPDGKVNFTEISKIASEKWKNISDKEKEKYNVLAQADKKRYTKEMEGYEPETDNRKPSKKAKREAKDPNKPKAPLTAFFFFSNEHRQTVKEKNPEFKVGDIAKVLGKMWSEC--KDKSKYEEMNKEAKEKY 501
            KP G  S+Y  + Q  REE+KKKNP   VNF+E SK  SE+W+ +S KEK K+  +A+ DK RY +EM+ Y P         K  ++ KDPN PK P +AFF F ++HR  VK  NP   +GDIAK LG+MWS+   K+KS YE+   + KEKY
Sbjct:    7 KPRGKTSSYAFFVQTCREEHKKKNPGTSVNFSEFSKKCSERWRTMSSKEKGKFEEMAKTDKVRYDREMKNYVPPK-----GAKGGKKKKDPNAPKRPPSAFFVFCSDHRPKVKGDNPGISIGDIAKKLGEMWSKLSPKEKSPYEQKAMKLKEKY 155

[Close]

BLAST of high mobility group-2 vs. Ensembl Zebrafish
Match: hmgb3b (high mobility group box 3b [Source:ZFIN;Acc:ZDB-GENE-050417-290])

HSP 1 Score: 125.176 bits (313), Expect = 1.135e-35
Identity = 63/140 (45.00%), Postives = 83/140 (59.29%), Query Frame = 1

Query:   46 KPSGAKSAYIIYTQAVREEYKKKNPDGKVNFTEISKIASEKWKNISDKEKEKYNVLAQADKKRYTKEMEGYEPETDNRKPSKKAKREAKDPNKPKAPLTAFFFFSNEHRQTVKEKNPEFKVGDIAKVLGKMWSECKDKSK 465
            KP G  SAY  + +  REE+ KKNP   VNF+E SK  SE+WK +S KEK K+  LA+ DK RY +EM  Y        P KK +++ KDPN P+ P + FF F  + R  +K +NP   +GD+AK LG MW+   D  K
Sbjct:    8 KPKGKMSAYAYFVKTCREEHNKKNPGVTVNFSEFSKKCSERWKTMSPKEKTKFEDLAKQDKARYDQEMMHYN-------PGKKGRKQKKDPNAPRRPPSGFFLFCAKQRPIIKAQNPSLGIGDVAKKLGGMWNNLSDSEK 140

[Close]

BLAST of high mobility group-2 vs. Ensembl Xenopus
Match: hmgb2 (high mobility group box 2 [Source:NCBI gene;Acc:394499])

HSP 1 Score: 133.265 bits (334), Expect = 3.881e-38
Identity = 76/162 (46.91%), Postives = 100/162 (61.73%), Query Frame = 1

Query:   46 KPSGAKSAYIIYTQAVREEYKKKNPDGKVNFTEISKIASEKWKNISDKEKEKYNVLAQADKKRYTKEMEGYEPETDNRKPSKKAKREAKDPNKPKAPLTAFFFFSNEHRQTVKEKNPEFKVGDIAKVLGKMWSE--CKDKSKYEEMNKEAKEKYNLAMLEYK 525
            KP G  S+Y  + Q  REE+KKK+PD  VNF E SK  SE+WK +S KEK K+  +A+ DK RY +EM+ Y P        +K  ++ KDPN PK P +AFF F +EHR  +K ++P   +GD AK LG+MWSE   KDK  YE+   + KEKY   +  YK
Sbjct:    8 KPRGKMSSYAYFVQTCREEHKKKHPDSSVNFAEFSKKCSERWKTMSAKEKSKFEEMAKNDKVRYEREMKTYIPPK-----GEKKGKKKKDPNAPKRPPSAFFLFCSEHRPQIKSESPGLSIGDTAKKLGEMWSEQTPKDKLPYEQKAAKLKEKYEKDVAAYK 164

[Close]

BLAST of high mobility group-2 vs. Ensembl Xenopus
Match: cep170b (centrosomal protein 170B [Source:Xenbase;Acc:XB-GENE-5943417])

HSP 1 Score: 132.88 bits (333), Expect = 4.837e-38
Identity = 75/165 (45.45%), Postives = 101/165 (61.21%), Query Frame = 1

Query:   37 NNKKPSGAKSAYIIYTQAVREEYKKKNPDGKVNFTEISKIASEKWKNISDKEKEKYNVLAQADKKRYTKEMEGYEPETDNRKPSKKAKREAKDPNKPKAPLTAFFFFSNEHRQTVKEKNPEFKVGDIAKVLGKMW--SECKDKSKYEEMNKEAKEKYNLAMLEYK 525
            + KKP G  S+Y  + Q  REE+KKK+PD  VNF E SK  SE+WK +S KEK K+  +A+ADK RY +EM+ Y P      P  + K++ KDPN PK P +AFF F +E R  +K ++P   +GDIAK LG+MW  +   DK  YE    + KEKY   +  Y+
Sbjct:    5 DPKKPRGKMSSYAYFVQTCREEHKKKHPDASVNFAEFSKKCSERWKTMSAKEKSKFEDMAKADKVRYEREMKTYIP------PKGETKKKFKDPNAPKRPPSAFFLFCSEFRPKIKGEHPGSTIGDIAKKLGEMWNNTATDDKLPYERKAAKLKEKYEKDVAAYR 163

[Close]

BLAST of high mobility group-2 vs. Ensembl Xenopus
Match: hmgb3 (high mobility group box 3 [Source:NCBI gene;Acc:448228])

HSP 1 Score: 123.635 bits (309), Expect = 1.353e-34
Identity = 71/157 (45.22%), Postives = 94/157 (59.87%), Query Frame = 1

Query:   64 SAYIIYTQAVREEYKKKNPDGKVNFTEISKIASEKWKNISDKEKEKYNVLAQADKKRYTKEMEGYEPETDNRKPSKKAKREAKDPNKPKAPLTAFFFFSNEHRQTVKEKNPEFKVGDIAKVLGKMWSECKDKSKYEEMNKEA--KEKYNLAMLEYKN 528
            SAY  + Q  REE+KKKNP+  VNF E SK  SE+WK +S KEK K++ LA+ADK RY +EM+ + P            ++ KDPN PK P + FF F +E R  +K  NP   +GD+AK LG+MW+   D  K    NK A  KEKY   + +YK+
Sbjct:   14 SAYAYFVQTCREEHKKKNPEIPVNFAEFSKKCSERWKTMSAKEKSKFDDLAKADKVRYDREMKDFGPVK--------KGKKKKDPNAPKRPPSGFFLFCSEFRPKIKSTNPGISIGDVAKKLGEMWNNLNDGEKQPYNNKAAKLKEKYEKDVADYKS 162

[Close]

BLAST of high mobility group-2 vs. Ensembl Xenopus
Match: hmgb3 (high mobility group box 3 [Source:NCBI gene;Acc:448228])

HSP 1 Score: 120.939 bits (302), Expect = 7.371e-34
Identity = 69/148 (46.62%), Postives = 89/148 (60.14%), Query Frame = 1

Query:   64 SAYIIYTQAVREEYKKKNPDGKVNFTEISKIASEKWKNISDKEKEKYNVLAQADKKRYTKEMEGYEPETDNRKPSKKAKREAKDPNKPKAPLTAFFFFSNEHRQTVKEKNPEFKVGDIAKVLGKMWSECKDKSKYEEMNKEA--KEKY 501
            SAY  + Q  REE+KKKNP+  VNF E SK  SE+WK +S KEK K++ LA+ADK RY +EM+ + P            ++ KDPN PK P + FF F +E R  +K  NP   +GD+AK LG+MW+   D  K    NK A  KEKY
Sbjct:   14 SAYAYFVQTCREEHKKKNPEIPVNFAEFSKKCSERWKTMSAKEKSKFDDLAKADKVRYDREMKDFGPVK--------KGKKKKDPNAPKRPPSGFFLFCSEFRPKIKSTNPGISIGDVAKKLGEMWNNLNDGEKQPYNNKAAKLKEKY 153

[Close]

BLAST of high mobility group-2 vs. Ensembl Xenopus
Match: abcb6 (ATP binding cassette subfamily B member 6 (Langereis blood group) [Source:Xenbase;Acc:XB-GENE-1001119])

HSP 1 Score: 54.6842 bits (130), Expect = 2.960e-8
Identity = 27/83 (32.53%), Postives = 48/83 (57.83%), Query Frame = 1

Query:  286 SKKAKREAKDPNKPKAPLTAFFFFSNEHRQTVKEKNPEFKVGDIAKVLGKMWSE--CKDKSKYEEMNKEAKEKYNLAMLEYKN 528
             +K KR  +D N PKAPLT +  F NE R+ ++ + P+    +I +++G  WS+    +K  Y +  ++ KE+Y   + +Y+N
Sbjct:   88 GRKRKRSPRDNNAPKAPLTGYVRFMNERREQLRTERPDVPFPEITRIVGSEWSKLPAHEKQHYLDEAEKDKERYTKELQQYQN 170

HSP 2 Score: 50.447 bits (119), Expect = 7.028e-7
Identity = 25/75 (33.33%), Postives = 42/75 (56.00%), Query Frame = 1

Query:   37 NNKKPSGAKSAYIIYTQAVREEYKKKNPDGKVNFTEISKIASEKWKNISDKEKEKYNVLAQADKKRYTKEMEGYE 261
            +N  P    + Y+ +    RE+ + + PD  V F EI++I   +W  +   EK+ Y   A+ DK+RYTKE++ Y+
Sbjct:   97 DNNAPKAPLTGYVRFMNERREQLRTERPD--VPFPEITRIVGSEWSKLPAHEKQHYLDEAEKDKERYTKELQQYQ 169

[Close]

BLAST of high mobility group-2 vs. Ensembl Mouse
Match: Hmgb1 (high mobility group box 1 [Source:MGI Symbol;Acc:MGI:96113])

HSP 1 Score: 132.109 bits (331), Expect = 7.864e-38
Identity = 78/172 (45.35%), Postives = 107/172 (62.21%), Query Frame = 1

Query:   43 KKPSGAKSAYIIYTQAVREEYKKKNPDGKVNFTEISKIASEKWKNISDKEKEKYNVLAQADKKRYTKEMEGYEPETDNRKPSKKAKREAKDPNKPKAPLTAFFFFSNEHRQTVKEKNPEFKVGDIAKVLGKMW--SECKDKSKYEEMNKEAKEKYNLAMLEYK-NGVPSAKK 549
            KKP G  S+Y  + Q  REE+KKK+PD  VNF+E SK  SE+WK +S KEK K+  +A+ADK RY +EM+ Y P      P  + K++ KDPN PK P +AFF F +E+R  +K ++P   +GD+AK LG+MW  +   DK  YE+   + KEKY   +  Y+  G P A K
Sbjct:   21 KKPRGKMSSYAFFVQTCREEHKKKHPDASVNFSEFSKKCSERWKTMSAKEKGKFEDMAKADKARYEREMKTYIP------PKGETKKKFKDPNAPKRPPSAFFLFCSEYRPKIKGEHPGLSIGDVAKKLGEMWNNTAADDKQPYEKKAAKLKEKYEKDIAAYRAKGKPDAAK 186

[Close]

BLAST of high mobility group-2 vs. Ensembl Mouse
Match: Hmgb1 (high mobility group box 1 [Source:MGI Symbol;Acc:MGI:96113])

HSP 1 Score: 132.109 bits (331), Expect = 8.488e-38
Identity = 78/174 (44.83%), Postives = 108/174 (62.07%), Query Frame = 1

Query:   37 NNKKPSGAKSAYIIYTQAVREEYKKKNPDGKVNFTEISKIASEKWKNISDKEKEKYNVLAQADKKRYTKEMEGYEPETDNRKPSKKAKREAKDPNKPKAPLTAFFFFSNEHRQTVKEKNPEFKVGDIAKVLGKMW--SECKDKSKYEEMNKEAKEKYNLAMLEYK-NGVPSAKK 549
            + KKP G  S+Y  + Q  REE+KKK+PD  VNF+E SK  SE+WK +S KEK K+  +A+ADK RY +EM+ Y P      P  + K++ KDPN PK P +AFF F +E+R  +K ++P   +GD+AK LG+MW  +   DK  YE+   + KEKY   +  Y+  G P A K
Sbjct:    5 DPKKPRGKMSSYAFFVQTCREEHKKKHPDASVNFSEFSKKCSERWKTMSAKEKGKFEDMAKADKARYEREMKTYIP------PKGETKKKFKDPNAPKRPPSAFFLFCSEYRPKIKGEHPGLSIGDVAKKLGEMWNNTAADDKQPYEKKAAKLKEKYEKDIAAYRAKGKPDAAK 172

[Close]

Query:   37 NNKKPSGAKSAYIIYTQAVREEYKKKNPDGKVNFTEISKIASEKWKNISDKEKEKYNVLAQADKKRYTKEMEGYEPETDNRKPSKKAKREAKDPNKPKAPLTAFFFFSNEHRQTVKEKNPEFKVGDIAKVLGKMW--SECKDKSKYEEMNKEAKEKYNLAMLEYK-NGVPSAKK 549
            + KKP G  S+Y  + Q  REE+KKK+PD  VNF+E SK  SE+WK +S KEK K+  +A+ADK RY +EM+ Y P      P  + K++ KDPN PK P +AFF F +E+R  +K ++P   +GD+AK LG+MW  +   DK  YE+   + KEKY   +  Y+  G P A K
Sbjct:    5 DPKKPRGKMSSYAFFVQTCREEHKKKHPDASVNFSEFSKKCSERWKTMSAKEKGKFEDMAKADKARYEREMKTYIP------PKGETKKKFKDPNAPKRPPSAFFLFCSEYRPKIKGEHPGLSIGDVAKKLGEMWNNTAADDKQPYEKKAAKLKEKYEKDIAAYRAKGKPDAAK 172

[Close]

Query:   37 NNKKPSGAKSAYIIYTQAVREEYKKKNPDGKVNFTEISKIASEKWKNISDKEKEKYNVLAQADKKRYTKEMEGYEPETDNRKPSKKAKREAKDPNKPKAPLTAFFFFSNEHRQTVKEKNPEFKVGDIAKVLGKMW--SECKDKSKYEEMNKEAKEKYNLAMLEYK-NGVPSAKK 549
            + KKP G  S+Y  + Q  REE+KKK+PD  VNF+E SK  SE+WK +S KEK K+  +A+ADK RY +EM+ Y P      P  + K++ KDPN PK P +AFF F +E+R  +K ++P   +GD+AK LG+MW  +   DK  YE+   + KEKY   +  Y+  G P A K
Sbjct:    5 DPKKPRGKMSSYAFFVQTCREEHKKKHPDASVNFSEFSKKCSERWKTMSAKEKGKFEDMAKADKARYEREMKTYIP------PKGETKKKFKDPNAPKRPPSAFFLFCSEYRPKIKGEHPGLSIGDVAKKLGEMWNNTAADDKQPYEKKAAKLKEKYEKDIAAYRAKGKPDAAK 172

[Close]

BLAST of high mobility group-2 vs. Ensembl Mouse
Match: Hmgb1 (high mobility group box 1 [Source:MGI Symbol;Acc:MGI:96113])

HSP 1 Score: 130.568 bits (327), Expect = 9.518e-38
Identity = 65/134 (48.51%), Postives = 90/134 (67.16%), Query Frame = 1

Query:   43 KKPSGAKSAYIIYTQAVREEYKKKNPDGKVNFTEISKIASEKWKNISDKEKEKYNVLAQADKKRYTKEMEGYEPETDNRKPSKKAKREAKDPNKPKAPLTAFFFFSNEHRQTVKEKNPEFKVGDIAKVLGKMWS 444
            KKP G  S+Y  + Q  REE+KKK+PD  VNF+E SK  SE+WK +S KEK K+  +A+ADK RY +EM+ Y P      P  + K++ KDPN PK P +AFF F +E+R  +K ++P   +GD+AK LG+MW+
Sbjct:    7 KKPRGKMSSYAFFVQTCREEHKKKHPDASVNFSEFSKKCSERWKTMSAKEKGKFEDMAKADKARYEREMKTYIP------PKGETKKKFKDPNAPKRPPSAFFLFCSEYRPKIKGEHPGLSIGDVAKKLGEMWN 134

[Close]

BLAST of high mobility group-2 vs. UniProt/SwissProt
Match: sp|P26584|HMGB2_CHICK (High mobility group protein B2 OS=Gallus gallus OX=9031 GN=HMGB2 PE=2 SV=2)

HSP 1 Score: 138.658 bits (348), Expect = 1.404e-39
Identity = 75/162 (46.30%), Postives = 99/162 (61.11%), Query Frame = 1

Query:   46 KPSGAKSAYIIYTQAVREEYKKKNPDGKVNFTEISKIASEKWKNISDKEKEKYNVLAQADKKRYTKEMEGYEPETDNRKPSKKAKREAKDPNKPKAPLTAFFFFSNEHRQTVKEKNPEFKVGDIAKVLGKMWSE--CKDKSKYEEMNKEAKEKYNLAMLEYK 525
            KP G  S+Y  + Q  REE+KKK+PD  VNF E S+  SE+WK +S KEK K+  +A+ DK RY +EM+ Y P      P  + K + KDPN PK P +AFF F +EHR  +K  +P   +GD AK LG+MWSE   KDK  YE+   + KEKY   +  Y+
Sbjct:    8 KPRGKMSSYAYFVQTCREEHKKKHPDSSVNFAEFSRKCSERWKTMSSKEKGKFEEMAKGDKARYDREMKNYVP------PKGEKKGKKKDPNAPKRPPSAFFLFCSEHRPKIKNDHPGLSIGDTAKKLGEMWSEQLAKDKQPYEQKAAKLKEKYEKDIAAYR 163

[Close]

BLAST of high mobility group-2 vs. UniProt/SwissProt
Match: sp|Q24537|HMG2_DROME (High mobility group protein DSP1 OS=Drosophila melanogaster OX=7227 GN=Dsp1 PE=2 SV=1)

HSP 1 Score: 141.739 bits (356), Expect = 6.155e-39
Identity = 75/165 (45.45%), Postives = 103/165 (62.42%), Query Frame = 1

Query:   40 NKKPSGAKSAYIIYTQAVREEYKKKNPDGKVNFTEISKIASEKWKNISDKEKEKYNVLAQADKKRYTKEMEGYEPETDNRKPSKKAKREAKDPNKPKAPLTAFFFFSNEHRQTVKEKNPEFKVGDIAKVLGKMWSEC--KDKSKYEEMNKEAKEKYNLAMLEYKN 528
            + KP G  +AY  + Q  REE+KKK+PD  V F E S+  +E+WK + DKEK++++ +A+ DK+RY  EM+ Y P         K +++ KDPN PK  L+AFF+F N+ R  VK  NPEF VGDIAK LG+ WS+   + K KYE M +  K +Y   M EYK 
Sbjct:  176 DAKPRGRMTAYAYFVQTCREEHKKKHPDETVIFAEFSRKCAERWKTMVDKEKKRFHEMAEKDKQRYEAEMQNYVPPKGAVVGRGKKRKQIKDPNAPKRSLSAFFWFCNDERNKVKALNPEFGVGDIAKELGRKWSDVDPEVKQKYESMAERDKARYEREMTEYKT 340

[Close]

BLAST of high mobility group-2 vs. UniProt/SwissProt
Match: sp|P63159|HMGB1_RAT (High mobility group protein B1 OS=Rattus norvegicus OX=10116 GN=Hmgb1 PE=1 SV=2)

HSP 1 Score: 132.109 bits (331), Expect = 5.938e-37
Identity = 78/174 (44.83%), Postives = 108/174 (62.07%), Query Frame = 1

Query:   37 NNKKPSGAKSAYIIYTQAVREEYKKKNPDGKVNFTEISKIASEKWKNISDKEKEKYNVLAQADKKRYTKEMEGYEPETDNRKPSKKAKREAKDPNKPKAPLTAFFFFSNEHRQTVKEKNPEFKVGDIAKVLGKMW--SECKDKSKYEEMNKEAKEKYNLAMLEYK-NGVPSAKK 549
            + KKP G  S+Y  + Q  REE+KKK+PD  VNF+E SK  SE+WK +S KEK K+  +A+ADK RY +EM+ Y P      P  + K++ KDPN PK P +AFF F +E+R  +K ++P   +GD+AK LG+MW  +   DK  YE+   + KEKY   +  Y+  G P A K
Sbjct:    5 DPKKPRGKMSSYAFFVQTCREEHKKKHPDASVNFSEFSKKCSERWKTMSAKEKGKFEDMAKADKARYEREMKTYIP------PKGETKKKFKDPNAPKRPPSAFFLFCSEYRPKIKGEHPGLSIGDVAKKLGEMWNNTAADDKQPYEKKAAKLKEKYEKDIAAYRAKGKPDAAK 172

[Close]

BLAST of high mobility group-2 vs. UniProt/SwissProt
Match: sp|B1MTB0|HMGB1_PLEMO (High mobility group protein B1 OS=Plecturocebus moloch OX=9523 GN=HMGB1 PE=3 SV=1)

HSP 1 Score: 132.109 bits (331), Expect = 5.938e-37
Identity = 78/174 (44.83%), Postives = 108/174 (62.07%), Query Frame = 1

Query:   37 NNKKPSGAKSAYIIYTQAVREEYKKKNPDGKVNFTEISKIASEKWKNISDKEKEKYNVLAQADKKRYTKEMEGYEPETDNRKPSKKAKREAKDPNKPKAPLTAFFFFSNEHRQTVKEKNPEFKVGDIAKVLGKMW--SECKDKSKYEEMNKEAKEKYNLAMLEYK-NGVPSAKK 549
            + KKP G  S+Y  + Q  REE+KKK+PD  VNF+E SK  SE+WK +S KEK K+  +A+ADK RY +EM+ Y P      P  + K++ KDPN PK P +AFF F +E+R  +K ++P   +GD+AK LG+MW  +   DK  YE+   + KEKY   +  Y+  G P A K
Sbjct:    5 DPKKPRGKMSSYAFFVQTCREEHKKKHPDASVNFSEFSKKCSERWKTMSAKEKGKFEDMAKADKARYEREMKTYIP------PKGETKKKFKDPNAPKRPPSAFFLFCSEYRPKIKGEHPGLSIGDVAKKLGEMWNNTAADDKQPYEKKAAKLKEKYEKDIAAYRAKGKPDAAK 172

[Close]

BLAST of high mobility group-2 vs. UniProt/SwissProt
Match: sp|A9RA84|HMGB1_PAPAN (High mobility group protein B1 OS=Papio anubis OX=9555 GN=HMGB1 PE=3 SV=1)

HSP 1 Score: 132.109 bits (331), Expect = 5.938e-37
Identity = 78/174 (44.83%), Postives = 108/174 (62.07%), Query Frame = 1

Query:   37 NNKKPSGAKSAYIIYTQAVREEYKKKNPDGKVNFTEISKIASEKWKNISDKEKEKYNVLAQADKKRYTKEMEGYEPETDNRKPSKKAKREAKDPNKPKAPLTAFFFFSNEHRQTVKEKNPEFKVGDIAKVLGKMW--SECKDKSKYEEMNKEAKEKYNLAMLEYK-NGVPSAKK 549
            + KKP G  S+Y  + Q  REE+KKK+PD  VNF+E SK  SE+WK +S KEK K+  +A+ADK RY +EM+ Y P      P  + K++ KDPN PK P +AFF F +E+R  +K ++P   +GD+AK LG+MW  +   DK  YE+   + KEKY   +  Y+  G P A K
Sbjct:    5 DPKKPRGKMSSYAFFVQTCREEHKKKHPDASVNFSEFSKKCSERWKTMSAKEKGKFEDMAKADKARYEREMKTYIP------PKGETKKKFKDPNAPKRPPSAFFLFCSEYRPKIKGEHPGLSIGDVAKKLGEMWNNTAADDKQPYEKKAAKLKEKYEKDIAAYRAKGKPDAAK 172

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BLAST of high mobility group-2 vs. TrEMBL
Match: I1ZIA1 (High mobility group-2 OS=Schmidtea mediterranea OX=79327 PE=2 SV=1)

HSP 1 Score: 353.599 bits (906), Expect = 5.615e-122
Identity = 176/177 (99.44%), Postives = 176/177 (99.44%), Query Frame = 1

Query:   34 MNNKKPSGAKSAYIIYTQAVREEYKKKNPDGKVNFTEISKIASEKWKNISDKEKEKYNVLAQADKKRYTKEMEGYEPETDNRKPSKKAKREAKDPNKPKAPLTAFFFFSNEHRQTVKEKNPEFKVGDIAKVLGKMWSECKDKSKYEEMNKEAKEKYNLAMLEYKNGVPSAKKSKAHV 564
            MNNKKPSGAKSAYIIYTQAVREEYKKKNPDGKVNFTEISKIASEKWKNISDKEKEKYNVLAQADKKRYTKEMEGYEPETDNRKPSKKAKREAKDPNKPKAPLTAFFFFSNEHRQTVKEKNPEFKVGDIAKVLGKMWSECKDKSKYEEMNKEAKEKYNLAMLEYKNG PSAKKSKAHV
Sbjct:    1 MNNKKPSGAKSAYIIYTQAVREEYKKKNPDGKVNFTEISKIASEKWKNISDKEKEKYNVLAQADKKRYTKEMEGYEPETDNRKPSKKAKREAKDPNKPKAPLTAFFFFSNEHRQTVKEKNPEFKVGDIAKVLGKMWSECKDKSKYEEMNKEAKEKYNLAMLEYKNGAPSAKKSKAHV 177

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BLAST of high mobility group-2 vs. TrEMBL
Match: I1ZIJ2 (High mobility group-1 OS=Schmidtea mediterranea OX=79327 PE=2 SV=1)

HSP 1 Score: 197.208 bits (500), Expect = 2.939e-60
Identity = 100/175 (57.14%), Postives = 128/175 (73.14%), Query Frame = 1

Query:   34 MNNKKPSGAKSAYIIYTQAVREEYKKKNPDGKVNFTEISKIASEKWKNISDKEKEKYNVLAQADKKRYTKEMEGYEPETDNRKPSKKAKREAKDPNKPKAPLTAFFFFSNEHRQTVKEKNPEFKVGDIAKVLGKMWSECKDKSKYEEMNKEAKEKYNLAMLEYKNGVPSAKKSKA 558
            M +KKP GAK+ Y  + Q VREE+KKK+PD ++ F+E SK  SEKWK +S KEK+++  +A  DK+RY KEM+ Y+P         K KR+ KDPNKPK   TAFFFFS+EHR+ +KE+NPE+KVGD+AKVLGKMW  CKDKSKYEE  K  KE+YN  + EYK+G P +KK+K 
Sbjct:    1 MVDKKPKGAKTPYACFVQVVREEHKKKHPDEQIVFSEFSKRCSEKWKEMSPKEKQRFMDIAAKDKERYLKEMDNYQPPAGT-----KNKRKIKDPNKPKGAWTAFFFFSDEHRKKIKEENPEYKVGDVAKVLGKMWEACKDKSKYEEQAKRDKERYNKELEEYKSGTPVSKKTKG 170

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BLAST of high mobility group-2 vs. TrEMBL
Match: A0A5J4NYU2 (Uncharacterized protein OS=Paragonimus westermani OX=34504 GN=DEA37_0014045 PE=4 SV=1)

HSP 1 Score: 152.14 bits (383), Expect = 3.115e-42
Identity = 73/171 (42.69%), Postives = 114/171 (66.67%), Query Frame = 1

Query:   22 VTKSMNNKKPSGAKSAYIIYTQAVREEYKKKNPDGKVNFTEISKIASEKWKNISDKEKEKYNVLAQADKKRYTKEMEGYEPETDNRKPSKKAKREAKDPNKPKAPLTAFFFFSNEHRQTVKEKNPEFKVGDIAKVLGKMWSECKDKSKYEEMNKEAKEKYNLAMLEYKNGV 534
            ++++ +  KP GA SAY  + Q +REE+KKK+P  ++ F++ SK  +E+WK ++ KEK+++  LA  DK+R+ +EM  Y P    +K   K ++  +DP  P+   +AFFFF +EHR  VKE NPE+KV D+AK LG+MW  C+DK+KYE + ++ K++Y   M +Y  GV
Sbjct:    1 MSRTKDKNKPKGAMSAYACFVQVIREEHKKKHPGEQIVFSDFSKKCAERWKLMTSKEKKRFEDLAALDKERFNREMSEYVPPEGMKK--GKKRKVPRDPGLPRRAWSAFFFFCDEHRGKVKENNPEYKVADVAKELGRMWETCQDKAKYELLAQQDKQRYEEDMAKYHAGV 169

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BLAST of high mobility group-2 vs. TrEMBL
Match: A0A2J7PFM2 (Uncharacterized protein OS=Cryptotermes secundus OX=105785 GN=B7P43_G15567 PE=4 SV=1)

HSP 1 Score: 151.369 bits (381), Expect = 4.043e-42
Identity = 83/175 (47.43%), Postives = 111/175 (63.43%), Query Frame = 1

Query:   40 NKKPSGAKSAYIIYTQAVREEYKKKNPDGKVNFTEISKIASEKWKNISDKEKEKYNVLAQADKKRYTKEMEGYEPETDNRKPSKKAKREAKDPNKPKAPLTAFFFFSNEHRQTVKEKNPEFKVGDIAKVLGKMWSECKD--KSKYEEMNKEAKEKYNLAMLEY----KNGVPSAK 546
            + KP G  +AY  + Q  REE+KKK+PD  V F E SK  +E+WK + DKEK++++ +A+ DKKRY  EMEGY P    +   KK ++  KDPN PK  L+AFF+F N+ R  VK  NPEF VGDIAK LG+ WS+     KSKYE M ++ K +Y+  M  Y    K G+P A+
Sbjct:    7 DAKPRGRMTAYAFFVQTCREEHKKKHPDENVIFAEFSKKCAERWKTMLDKEKKRFHEMAEKDKKRYDSEMEGYTPAKGEKARGKK-RKHVKDPNAPKRSLSAFFWFCNDERSKVKALNPEFGVGDIAKELGRRWSDVDPELKSKYEAMAEKDKARYDREMTAYKKRPKGGMPVAQ 180

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BLAST of high mobility group-2 vs. TrEMBL
Match: A0A4S2M7M8 (Uncharacterized protein OS=Opisthorchis felineus OX=147828 GN=CRM22_002095 PE=4 SV=1)

HSP 1 Score: 150.984 bits (380), Expect = 8.882e-42
Identity = 72/163 (44.17%), Postives = 110/163 (67.48%), Query Frame = 1

Query:   46 KPSGAKSAYIIYTQAVREEYKKKNPDGKVNFTEISKIASEKWKNISDKEKEKYNVLAQADKKRYTKEMEGYEPETDNRKPSKKAKREAKDPNKPKAPLTAFFFFSNEHRQTVKEKNPEFKVGDIAKVLGKMWSECKDKSKYEEMNKEAKEKYNLAMLEYKNGV 534
            +P GA SAY  + Q +REE+KKK+P  ++ F++ SK  +E+WK ++ KEK+++  LA  DK+R+ +EM  Y P    +K   K ++  +DP  P+   +AFFFF +EHR  VKE NPEFKV D+AK LG+ W  C+DK+KYE + ++ K++Y   M++Y+ GV
Sbjct:    9 RPKGAMSAYACFVQVIREEHKKKHPGEQIVFSDFSKKCAERWKLMTPKEKKRFEDLAALDKERFNREMSDYVPPEGMKK--GKKRKVPRDPGLPRRAWSAFFFFCDEHRGKVKENNPEFKVADVAKELGRQWEACQDKAKYELLAQQDKQRYEEDMVKYRAGV 169

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BLAST of high mobility group-2 vs. Ensembl Cavefish
Match: hmgb2a (high mobility group box 2 [Source:NCBI gene;Acc:111195933])

HSP 1 Score: 130.568 bits (327), Expect = 1.953e-37
Identity = 79/175 (45.14%), Postives = 106/175 (60.57%), Query Frame = 1

Query:   46 KPSGAKSAYIIYTQAVREEYKKKNPDGKVNFTEISKIASEKWKNISDKEKEKYNVLAQADKKRYTKEMEGYEPETDNRKPSKKAKREAKDPNKPKAPLTAFFFFSNEHRQTVKEKNPEFKVGDIAKVLGKMWSE--CKDKSKYEEMNKEAKEKYNLAMLEYKNGVPSAKKSKAHV 564
            KP G  S+Y  + Q  REE+KKK+P   VNF E SK  +E+WK +S KEK K+  LA+ DK RY +EM+ Y P         K  ++ KDPN PK P +AFF F ++HR  VK ++P   +GDIAK LG+MWS+   KDK+ YE+   + KEKY   +  Y+     AK +KA V
Sbjct:    7 KPRGKTSSYAFFVQTCREEHKKKHPGTSVNFAEFSKKCAERWKTMSPKEKTKFEDLAKNDKVRYDREMKTYIPPK-----GAKKGKKKKDPNAPKRPPSAFFVFCSDHRPKVKSEHPGISIGDIAKKLGEMWSKQSPKDKAPYEQKAMKLKEKYEKDVAAYR-----AKGAKADV 171

[Close]

BLAST of high mobility group-2 vs. Ensembl Cavefish
Match: hmgb1a (high mobility group-T protein-like [Source:NCBI gene;Acc:103039534])

HSP 1 Score: 128.642 bits (322), Expect = 8.546e-37
Identity = 74/164 (45.12%), Postives = 101/164 (61.59%), Query Frame = 1

Query:   46 KPSGAKSAYIIYTQAVREEYKKKNPDGKVNFTEISKIASEKWKNISDKEKEKYNVLAQADKKRYTKEMEGYEPETDNRKPSKKAKREAKDPNKPKAPLTAFFFFSNEHRQTVKEKNPEFKVGDIAKVLGKMW--SECKDKSKYEEMNKEAKEKYNLAMLEYKNG 531
            KP G  S+Y  + Q  REE+KKK+PD  VNF+E SK  SE+WK +S KEK K+  +A+ DK RY +EM+ Y P      P  + K+  KDPN PK P +AFF F  E+R  VKE+ P   +GD+AK LG+MW  +  ++K  YE+   + KEKY   +  Y+ G
Sbjct:    7 KPRGKMSSYAYFVQTCREEHKKKHPDTSVNFSEFSKKCSERWKTMSAKEKGKFEEMARLDKARYEREMKNYVP------PRGEKKKRFKDPNAPKRPPSAFFIFCAEYRPKVKEETPGLSIGDVAKKLGEMWNKTSAEEKQPYEKKAAKLKEKYEKDIAAYRKG 164

[Close]

BLAST of high mobility group-2 vs. Ensembl Cavefish
Match: ENSAMXT00000044228.1 (high mobility group protein B2-like [Source:NCBI gene;Acc:103034313])

HSP 1 Score: 127.102 bits (318), Expect = 4.453e-36
Identity = 73/171 (42.69%), Postives = 103/171 (60.23%), Query Frame = 1

Query:   46 KPSGAKSAYIIYTQAVREEYKKKNPDGKVNFTEISKIASEKWKNISDKEKEKYNVLAQADKKRYTKEMEGYEPETDNRKPSKKAKREAKDPNKPKAPLTAFFFFSNEHRQTVKEKNPEFKVGDIAKVLGKMWSEC--KDKSKYEEMNKEAKEKYNLAMLEYKNGVPSAKKS 552
            KP G  SAY  +  + R+E KKK+P   VNF + SK  SE WK ++  EK+K+  LA+ADK RY +EM+ Y P     K   K  R+ KDPN PK P +AFF F +EHR  VK ++P   +G+IAK LG+ WS+   KD+S +++     +EKY   +  Y++G   AK+ 
Sbjct:    7 KPKGRTSAYAFFVLSSRDELKKKSPGTSVNFGKFSKKCSEDWKALTPSEKKKFEDLAKADKARYDEEMKSYVPP----KGMGKMGRKKKDPNAPKRPPSAFFIFCSEHRPAVKSEHPNLTIGEIAKKLGEKWSKLSTKDRSPFDQKAVLLREKYEKEVAAYRSGGSVAKRG 173

[Close]

BLAST of high mobility group-2 vs. Ensembl Cavefish
Match: hmgb1b (high mobility group protein B1-like [Source:NCBI gene;Acc:103041093])

HSP 1 Score: 125.561 bits (314), Expect = 1.323e-35
Identity = 63/134 (47.01%), Postives = 87/134 (64.93%), Query Frame = 1

Query:   43 KKPSGAKSAYIIYTQAVREEYKKKNPDGKVNFTEISKIASEKWKNISDKEKEKYNVLAQADKKRYTKEMEGYEPETDNRKPSKKAKREAKDPNKPKAPLTAFFFFSNEHRQTVKEKNPEFKVGDIAKVLGKMWS 444
            +KP G  S+Y  + Q  REE+KKK+P+  VNF+E SK  SE+WK +S KEK K+  +A+ DK RY +EM+ Y P      P  + K+  KDPN PK P +AFF F  ++R  +K +NP   +GDIAK LG+MW+
Sbjct:    6 RKPRGKMSSYAYFVQTCREEHKKKHPEASVNFSEFSKKCSERWKTMSPKEKSKFEDMAKQDKVRYEREMKNYIP------PKGEKKKRFKDPNAPKRPPSAFFIFCGDYRPKIKGENPGLSIGDIAKKLGEMWN 133

[Close]

BLAST of high mobility group-2 vs. Ensembl Cavefish
Match: hmgb3a (high mobility group protein B3 [Source:NCBI gene;Acc:103036962])

HSP 1 Score: 114.775 bits (286), Expect = 2.523e-31
Identity = 65/164 (39.63%), Postives = 95/164 (57.93%), Query Frame = 1

Query:   43 KKPSGAKSAYIIYTQAVREEYKKKNPDGKVNFTEISKIASEKWKNISDKEKEKYNVLAQADKKRYTKEMEGYEPETDNRKPSKKAKREAKDPNKPKAPLTAFFFFSNEHRQTVKEKNPEFKVGDIAKVLGKMWSECKDKSK--YEEMNKEAKEKYNLAMLEYKN 528
            +KP G  SAY  + Q  REE+K K+P+  VNF E SK  S +WK +S KEK ++  +A+ DK RY +EM  Y          K+ K+  KDPN PK P + FF F ++HR  +K + P   +G++AK LG+MW+   D  K  Y   + + K+KY   + +YK+
Sbjct:    7 RKPKGKMSAYAYFVQTCREEHKLKSPEIPVNFAEFSKKCSVRWKAMSGKEKTRFEDMAKQDKVRYDQEMMHYT--------GKRGKK--KDPNAPKRPPSGFFIFCSDHRPKIKAQYPHMGIGEVAKKLGEMWNNLTDAHKQPYVMKSNKLKDKYQQDIADYKS 160

[Close]

BLAST of high mobility group-2 vs. Ensembl Sea Lamprey
Match: hmgb2b (high mobility group box 2b [Source:ZFIN;Acc:ZDB-GENE-040912-122])

HSP 1 Score: 129.798 bits (325), Expect = 8.629e-38
Identity = 69/157 (43.95%), Postives = 96/157 (61.15%), Query Frame = 1

Query:   64 SAYIIYTQAVREEYKKKNPDGKVNFTEISKIASEKWKNISDKEKEKYNVLAQADKKRYTKEMEGYEPETDNRKPSKKAKREAKDPNKPKAPLTAFFFFSNEHRQTVKEKNPEFKVGDIAKVLGKMW--SECKDKSKYEEMNKEAKEKYNLAMLEYKN 528
            S+Y  + Q  REE+KKKNP+  VNF E SK  SE+WK +S+KEK ++  +A+ DK RY +EM+ Y P    R       R+ KDPN PK P +AFF +  E+R  V+ +NP   +G IAK LG+MW  +   +KS YE    + KEKY+  M  Y++
Sbjct:   14 SSYAYFVQTCREEHKKKNPEASVNFAEFSKKCSERWKTMSEKEKTRFEDMAKVDKVRYDREMKTYVPPKGER-----GSRKKKDPNAPKRPPSAFFIYCAEYRSKVRAENPGLTIGSIAKKLGEMWNNAPADEKSIYERKTAKLKEKYDKDMASYRS 165

[Close]

BLAST of high mobility group-2 vs. Ensembl Sea Lamprey
Match: hmgb2a (high mobility group box 2a [Source:ZFIN;Acc:ZDB-GENE-051120-126])

HSP 1 Score: 128.642 bits (322), Expect = 1.345e-37
Identity = 64/133 (48.12%), Postives = 85/133 (63.91%), Query Frame = 1

Query:   46 KPSGAKSAYIIYTQAVREEYKKKNPDGKVNFTEISKIASEKWKNISDKEKEKYNVLAQADKKRYTKEMEGYEPETDNRKPSKKAKREAKDPNKPKAPLTAFFFFSNEHRQTVKEKNPEFKVGDIAKVLGKMWS 444
            KP G  S+Y  + Q  REE+KKK+P+  VNF E SK  SE+WK +S KEK ++  +A+ADK R+ +EM+ Y P         K KR+ KDPN PK P +AFF F +EHR  VK  +P   +G+IAK LG+MW 
Sbjct:    8 KPRGKMSSYAYFVQTCREEHKKKHPEASVNFAEFSKKCSERWKTMSPKEKARFEEMAKADKARFDREMKNYVPP--------KGKRKTKDPNAPKRPPSAFFVFCSEHRPKVKADHPGLGIGEIAKRLGEMWG 132

[Close]

BLAST of high mobility group-2 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000005794.1 (pep scaffold:Pmarinus_7.0:GL478246:10745:21158:-1 gene:ENSPMAG00000005214.1 transcript:ENSPMAT00000005794.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 50.0618 bits (118), Expect = 1.613e-7
Identity = 33/121 (27.27%), Postives = 60/121 (49.59%), Query Frame = 1

Query:  130 VNFTEISKIASEKWKNISDKEKEKYNVLAQADKKRYTKEMEGY-EPETDNRKPSKKAKREAKDPNK----------------PKAPLTAFFFFSNEHRQTVKEKNPEFKVGDIAKVLGKMW 441
            V  TE     S +WK +S KEK+ Y+   +  KK+Y  + + + E  TD  +   + +  AK+  K                P+ P++A F FS E R+ +++KNP+    ++ ++L ++W
Sbjct:  318 VPSTERMHECSRQWKVLSPKEKDAYHKRCEQKKKQYEIDFQKFVENLTDEERERIQMEERAKEGGKMASLATAAALESAVDRPQRPISAMFIFSQEKRKKLRKKNPDLPESELTRLLARLW 438

HSP 2 Score: 47.3654 bits (111), Expect = 1.169e-6
Identity = 42/165 (25.45%), Postives = 82/165 (49.70%), Query Frame = 1

Query:   49 PSGAKSAYIIYTQAVREEYKKKNPDGKVNFTEISKIASEKWKNISDKEKEKYNVLAQADKKRYTKEMEGYEPETDNRKPSKKAKREAKDPNKPKAPLTAFFFFSNEHRQTVKEKNPEFKVGDIAKVLGKMWSECKDKSKYEEMNK--EAKEKYNLAMLEYKNGVP 537
            P    + Y  +  A R +Y K +PD  +   +++KI S K+K +++K+K KY    Q DK+ + K M  +  +  +    + A R++  P KPK P   ++   +  ++   + +PE  + ++ + L + WS   DK + + + K  E + ++ L + EY    P
Sbjct:  113 PKKPLTPYFRFFMAKRAKYAKMHPD--LTNLDLTKILSTKYKEMTEKKKLKYMEDYQRDKEEFDKAMAKFREQHPDL--VEVAVRKSDVPEKPKTPQQLWY---HHEKKAYMKLHPEMNLKEVNETLRRQWSVLPDKKRLKWIAKALELQRQHALELKEYICTHP 270

[Close]

BLAST of high mobility group-2 vs. Ensembl Sea Lamprey
Match: smarce1 (SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1 [Source:ZFIN;Acc:ZDB-GENE-030131-967])

HSP 1 Score: 44.2838 bits (103), Expect = 9.640e-6
Identity = 25/73 (34.25%), Postives = 37/73 (50.68%), Query Frame = 1

Query:  310 KDPNKPKAPLTAFFFFSNEHRQTVKEKNPEFKVGDIAKVLGKMWSECKDKSKYEEMNKEAKEK--YNLAMLEY 522
            K P  P  PL  +  +S +    VK  NP+ K+ +I K++G MW +  ++ K E +N    EK  YN  M  Y
Sbjct:   65 KAPKAPDKPLMPYMRYSRKVWDQVKAANPDLKLWEIGKIIGSMWRDLSEEDKQEYLNDYEAEKIEYNDLMKAY 137

[Close]

BLAST of high mobility group-2 vs. Ensembl Yeast
Match: NHP6B (High-mobility group (HMG) protein; binds to and remodels nucleosomes; involved in recruiting FACT and other chromatin remodelling complexes to the chromosomes; functionally redundant with Nhp6Ap; required for transcriptional initiation fidelity of some tRNA genes; homologous to mammalian HMGB1 and HMGB2; NHP6B has a paralog, NHP6A, that arose from the whole genome duplication [Source:SGD;Acc:S000002157])

HSP 1 Score: 61.2326 bits (147), Expect = 5.946e-13
Identity = 28/75 (37.33%), Postives = 45/75 (60.00%), Query Frame = 1

Query:  283 PSKKAKREAKDPNKPKAPLTAFFFFSNEHRQTVKEKNPEFKVGDIAKVLGKMWS--ECKDKSKYEEMNKEAKEKY 501
            P K+  R  KDPN PK  L+A+ FF+NE+R  V+ +NP+   G + ++LG+ W     ++K  YE   +  K++Y
Sbjct:   13 PKKRTTRRKKDPNAPKRGLSAYMFFANENRDIVRSENPDVTFGQVGRILGERWKALTAEEKQPYESKAQADKKRY 87

HSP 2 Score: 53.5286 bits (127), Expect = 3.541e-10
Identity = 28/70 (40.00%), Postives = 41/70 (58.57%), Query Frame = 1

Query:   49 PSGAKSAYIIYTQAVREEYKKKNPDGKVNFTEISKIASEKWKNISDKEKEKYNVLAQADKKRYTKEMEGY 258
            P    SAY+ +    R+  + +NPD  V F ++ +I  E+WK ++ +EK+ Y   AQADKKRY  E E Y
Sbjct:   27 PKRGLSAYMFFANENRDIVRSENPD--VTFGQVGRILGERWKALTAEEKQPYESKAQADKKRYESEKELY 94

[Close]

BLAST of high mobility group-2 vs. Ensembl Yeast
Match: ABF2 (Mitochondrial DNA-binding protein; involved in mitochondrial DNA replication and recombination, member of HMG1 DNA-binding protein family; activity may be regulated by protein kinase A phosphorylation; ABF2 has a paralog, IXR1, that arose from the whole genome duplication; human homolog TFAM can complement yeast abf2 mutant, rescuing the loss-of-mitochondrial DNA phenotype in a yeast abf2 strain [Source:SGD;Acc:S000004676])

HSP 1 Score: 62.7734 bits (151), Expect = 9.770e-13
Identity = 50/154 (32.47%), Postives = 76/154 (49.35%), Query Frame = 1

Query:   49 PSGAKSAYIIYTQAVREEYKKKNPDGKVNFTEISKIASEKWKNISDKEKEKYNVLAQADKKRYTKEMEGYEPETDNRKPSKKAKREAKDPNKPKAPLTAFFFFSNEHRQTVKEKNPEFKVGDIAKVLGKMWSECKD--KSKYEEMNKEAKEKYN 504
            P    SAY +Y Q  R ++ K+NP  +    EISKIA EKW+N+    KEKY     +++K+   E +             KAK+E  +   PK P   F  ++NE R  V  ++P+    D+ K++G  W       K KY +  K+A ++YN
Sbjct:   43 PKRPTSAYFLYLQDHRSQFVKENPTLRP--AEISKIAGEKWQNLEADIKEKYI----SERKKLYSEYQ-------------KAKKEFDEKLPPKKPAGPFIKYANEVRSQVFAQHPDKSQLDLMKIIGDKWQSLDQSIKDKYIQEYKKAIQEYN 177

[Close]

BLAST of high mobility group-2 vs. Ensembl Yeast
Match: IXR1 (Transcriptional repressor that regulates hypoxic genes during normoxia; involved in the aerobic repression of genes such as COX5b, TIR1, and HEM13; binds DNA intrastrand cross-links formed by cisplatin; HMG (high mobility group box) domain containing protein which binds and bends cisplatin-modified DNA, blocking excision repair; IXR1 has a paralog, ABF2, that arose from the whole genome duplication [Source:SGD;Acc:S000001515])

HSP 1 Score: 60.4622 bits (145), Expect = 3.294e-11
Identity = 41/143 (28.67%), Postives = 74/143 (51.75%), Query Frame = 1

Query:   43 KKPSGAKSAYIIYTQAVREEYKKKNPDGKVNFTEISKIASEKWKNISDKEKEKYNVLAQADKKRYTKEMEGYEPETDNRKPSKKAKREAKDPNKPKAPLTAFFFFSNEHRQTVKEKNPEFKVGDIAKVLGKMWSECKDKSKYE 471
            K+PS   SAY +++ ++R E  ++ P+ KV   E+SK+AS +WK ++D +K+ +    + + ++Y    + YE              +   P +P  P   F  F+ E R TV ++NP+  + +I K++G+ W E     K E
Sbjct:  362 KRPS---SAYFLFSMSIRNELLQQFPEAKV--PELSKLASARWKELTDDQKKPFYEEFRTNWEKYRVVRDAYE--------------KTLPPKRPSGP---FIQFTQEIRPTVVKENPDKGLIEITKIIGERWRELDPAKKAE 482

[Close]

BLAST of high mobility group-2 vs. Ensembl Yeast
Match: NHP6A (High-mobility group (HMG) protein; binds to and remodels nucleosomes; involved in recruiting FACT and other chromatin remodelling complexes to chromosomes; functionally redundant with Nhp6Bp; required for transcriptional initiation fidelity of some tRNA genes; homologous to mammalian HMGB1 and HMGB2; NHP6A has a paralog, NHP6B, that arose from the whole genome duplication; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000006256])

HSP 1 Score: 54.299 bits (129), Expect = 1.556e-10
Identity = 30/77 (38.96%), Postives = 47/77 (61.04%), Query Frame = 1

Query:  277 RKPSKKAKREAKDPNKPKAPLTAFFFFSNEHRQTVKEKNPEFKVGDIAKVLGKMWSEC--KDKSKYEEMNKEAKEKY 501
            R+P K+  R+ KDPN PK  L+A+ FF+NE+R  V+ +NP+   G + K LG+ W     ++K  YE   +  K++Y
Sbjct:    5 REPKKRTTRKKKDPNAPKRALSAYMFFANENRDIVRSENPDITFGQVGKKLGEKWKALTPEEKQPYEAKAQADKKRY 81

HSP 2 Score: 53.1434 bits (126), Expect = 5.232e-10
Identity = 29/70 (41.43%), Postives = 41/70 (58.57%), Query Frame = 1

Query:   49 PSGAKSAYIIYTQAVREEYKKKNPDGKVNFTEISKIASEKWKNISDKEKEKYNVLAQADKKRYTKEMEGY 258
            P  A SAY+ +    R+  + +NPD  + F ++ K   EKWK ++ +EK+ Y   AQADKKRY  E E Y
Sbjct:   21 PKRALSAYMFFANENRDIVRSENPD--ITFGQVGKKLGEKWKALTPEEKQPYEAKAQADKKRYESEKELY 88

[Close]

BLAST of high mobility group-2 vs. Ensembl Nematostella
Match: EDO36028 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SJW6])

HSP 1 Score: 119.013 bits (297), Expect = 1.055e-33
Identity = 73/173 (42.20%), Postives = 111/173 (64.16%), Query Frame = 1

Query:   46 KPSGAKSAYIIYTQAVREEYKKKNPDGKVNFTEISKIASEKWKNISDKEKEKYNVLAQADKKRYTKEMEGYEPETDNRKPSKKAKREAKDPNKPKAPLTAFFFFSNEHRQTVKEKNPEFKVGDIAKVLGKMWSEC--KDKSKYEEMNKEAKEKYNLAMLEYKNGVPSAKKSKA 558
            KP GAKSAY  + Q  RE+ +++  +GK +  + SK+++EKWKN+S++EKE +   A  DK+R+ +EM+ Y P        KK K++ KDPNKPK  L+A+F F N  R  VK+ NP    G ++KVLG+MWS+    DK++Y++M K+ K +Y   M  +K+G   AK++K 
Sbjct:    2 KPKGAKSAYNFFLQDQREKLQRE--EGKFSLADFSKVSAEKWKNMSEEEKETFVQKAGKDKERFKEEMQSYTPPPSEESGKKKRKKQTKDPNKPKRCLSAYFHFINLKRDDVKKDNPNASGGALSKVLGEMWSKMTDDDKTQYQDMAKKDKVRYESEMKAFKDGKLPAKQNKT 172

[Close]

BLAST of high mobility group-2 vs. Ensembl Nematostella
Match: EDO39305 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SAG5])

HSP 1 Score: 58.9214 bits (141), Expect = 5.684e-12
Identity = 28/66 (42.42%), Postives = 41/66 (62.12%), Query Frame = 1

Query:  325 PKAPLTAFFFFSNEHRQTVKEKNPEFKVGDIAKVLGKMWSECKDKSKYEEMNKEAKEKYNLAMLEY 522
            PK  ++A+  + N+ RQ +K+KNP   V +++KV G+MW    DKSK+EE     K+KY   M EY
Sbjct:    1 PKRAMSAYMLWLNDTRQEIKDKNPGISVTEVSKVAGEMWKNLTDKSKWEEKAAIEKQKYVQRMKEY 66

HSP 2 Score: 51.9878 bits (123), Expect = 2.000e-9
Identity = 28/70 (40.00%), Postives = 44/70 (62.86%), Query Frame = 1

Query:   49 PSGAKSAYIIYTQAVREEYKKKNPDGKVNFTEISKIASEKWKNISDKEKEKYNVLAQADKKRYTKEMEGY 258
            P  A SAY+++    R+E K KNP   ++ TE+SK+A E WKN++D  K K+   A  +K++Y + M+ Y
Sbjct:    1 PKRAMSAYMLWLNDTRQEIKDKNPG--ISVTEVSKVAGEMWKNLTD--KSKWEEKAAIEKQKYVQRMKEY 66

[Close]

BLAST of high mobility group-2 vs. Ensembl Nematostella
Match: EDO41032 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S5L8])

HSP 1 Score: 61.6178 bits (148), Expect = 1.852e-11
Identity = 31/82 (37.80%), Postives = 49/82 (59.76%), Query Frame = 1

Query:  286 SKKAKREAKDPNKPKAPLTAFFFFSNEHRQTVKEKNPEFKVGDIAKVLGKMWSEC--KDKSKYEEMNKEAKEKYNLAMLEYK 525
             +K K+  KD N PKAPLT +  F NEHR+ V+ +NP+    ++ ++LG MWS+     K  + E  ++ KE+Y   + EY+
Sbjct:    2 GRKRKKAHKDVNAPKAPLTGYVRFLNEHREKVRSENPDLPFHEVTRILGNMWSQLPTPQKQLFLEEAEKDKERYMKELEEYQ 83

[Close]

BLAST of high mobility group-2 vs. Ensembl Nematostella
Match: EDO47230 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RMY4])

HSP 1 Score: 57.3806 bits (137), Expect = 5.524e-10
Identity = 28/82 (34.15%), Postives = 48/82 (58.54%), Query Frame = 1

Query:  286 SKKAKREAKDPNKPKAPLTAFFFFSNEHRQTVKEKNPEFKVGDIAKVLGKMWSECK--DKSKYEEMNKEAKEKYNLAMLEYK 525
             K+ ++  +D N PKAPLT +  F NE R+ V+ ++PE    ++ K+LG  WS+    DK +Y +  +  KE+Y + +  Y+
Sbjct:    8 GKRRRKTLRDTNAPKAPLTGYVQFLNEQREKVRSEHPELPFPEVTKILGAEWSKMSQDDKQRYLDDAERDKERYIIELENYQ 89

[Close]

BLAST of high mobility group-2 vs. Ensembl Nematostella
Match: EDO40495 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S799])

HSP 1 Score: 48.521 bits (114), Expect = 5.520e-7
Identity = 33/88 (37.50%), Postives = 47/88 (53.41%), Query Frame = 1

Query:  310 KDPNKPKAPLTAFFFFSNEHRQTVKE--KNPEFKVG--DIAKVLGKMWSEC--KDKSKYEEMNKEAKEKYNLAMLEYKNGVPSAKKSK 555
            KDPN PK P  AFF F  + R  ++E  K+    +G  ++ K L K W+     +K  Y EM +  KE+Y L M +Y +  P +KK K
Sbjct:  109 KDPNAPKKPANAFFMFCQQQRTVMQEDHKDATAVMGHHELTKSLAKEWNNLLPDEKKVYYEMYERDKERYELEMKQYSSDKPPSKKQK 196

[Close]

BLAST of high mobility group-2 vs. Ensembl Medaka
Match: hmgb2a (high mobility group protein B2 [Source:NCBI gene;Acc:101157589])

HSP 1 Score: 133.265 bits (334), Expect = 1.891e-38
Identity = 77/170 (45.29%), Postives = 102/170 (60.00%), Query Frame = 1

Query:   22 VTKSMNNKKPSGAKSAYIIYTQAVREEYKKKNPDGKVNFTEISKIASEKWKNISDKEKEKYNVLAQADKKRYTKEMEGYEPETDNRKPSKKAKREAKDPNKPKAPLTAFFFFSNEHRQTVKEKNPEFKVGDIAKVLGKMWS--ECKDKSKYEEMNKEAKEKYNLAMLEYK 525
            +TK  N  KP G  SAY  +    REE+KKK+P   VNF E SK  SE+WK +S KEK K++ LA+ DK RY +EM+ Y P         K  ++ KDPN PK P +AFF F ++HR  +KE NP   +GDIAK LG++W+    KDK+ YE    + KEKY   +  Y+
Sbjct:    1 MTKDPN--KPRGKTSAYAYFVATCREEHKKKHPGTSVNFAEFSKKCSERWKTMSSKEKVKFDELAKTDKARYDREMKTYVPPK-----GAKKVKKKKDPNAPKRPPSAFFVFCSDHRPKIKEDNPGISIGDIAKKLGELWATQSAKDKAPYEAKAAKLKEKYEKDVAAYR 163

[Close]

BLAST of high mobility group-2 vs. Ensembl Medaka
Match: hmgb1b (high mobility group protein B1 [Source:NCBI gene;Acc:101156596])

HSP 1 Score: 125.561 bits (314), Expect = 1.025e-35
Identity = 72/166 (43.37%), Postives = 102/166 (61.45%), Query Frame = 1

Query:   37 NNKKPSGAKSAYIIYTQAVREEYKKKNPDGKVNFTEISKIASEKWKNISDKEKEKYNVLAQADKKRYTKEMEGYEPETDNRKPSKKAKREAKDPNKPKAPLTAFFFFSNEHRQTVKEKNPEFKVGDIAKVLGKMW--SECKDKSKYEEMNKEAKEKYNLAMLEYKN 528
            + KKP G  S+Y  + Q  REE+KKK+PD  VNF+E SK  SE+WK +S KEK K+  +A+ DK RY +EM+ Y P      P  + K+  KDPN PK P +AFF F  + R  +K ++P   +GD AK LG+MW  S  ++K  YE+   + KEKY+  ++ Y+ 
Sbjct:    4 DPKKPRGKMSSYAYFVQTCREEHKKKHPDASVNFSEFSKKCSERWKTMSPKEKGKFEDMAKQDKVRYEREMKNYVP------PKGQKKKRFKDPNAPKRPPSAFFLFCADFRPKIKSESPGLSIGDTAKKLGEMWNSSSAEEKQPYEKKAAKLKEKYDKDIVAYRT 163

[Close]

BLAST of high mobility group-2 vs. Ensembl Medaka
Match: hmgb1a (high mobility group-T protein [Source:NCBI gene;Acc:101165167])

HSP 1 Score: 124.02 bits (310), Expect = 7.030e-35
Identity = 74/163 (45.40%), Postives = 100/163 (61.35%), Query Frame = 1

Query:   46 KPSGAKSAYIIYTQAVREEYKKKNPDGKVNFTEISKIASEKWKNISDKEKEKYNVLAQADKKRYTKEMEGYEPETDNRKPSKKAK-REAKDPNKPKAPLTAFFFFSNEHRQTVKEKNPEFKVGDIAKVLGKMW--SECKDKSKYEEMNKEAKEKYNLAMLEYK 525
            KP G  S+Y  + Q  REE+KKK+PD  VNF E SK  SE+WK +S KEK K+  +A+ DK RY +EM  Y        P+K AK ++ KDPN PK P +AFF F +E R  VK ++P   +GD+AK LG+MW  +  +DK  YE+   + KEKY   +  Y+
Sbjct:    7 KPRGKMSSYAYFVQTCREEHKKKHPDASVNFAEFSKKCSERWKTMSAKEKGKFEDMARQDKVRYDREMMSYV-------PAKGAKTKKFKDPNAPKRPPSAFFIFCSEFRPKVKGESPGLTIGDVAKRLGEMWNSTSAEDKQPYEKKAAKLKEKYGKDIAAYR 162

[Close]

BLAST of high mobility group-2 vs. Ensembl Medaka
Match: ubtf (upstream binding transcription factor [Source:NCBI gene;Acc:101156013])

HSP 1 Score: 57.3806 bits (137), Expect = 3.149e-9
Identity = 39/139 (28.06%), Postives = 63/139 (45.32%), Query Frame = 1

Query:  130 VNFTEISKIASEKWKNISDKEKEKYNVLAQADKKRYTKEMEGY---------------------------EPETDNRKPSKKAKREAKDPNKPKAPLTAFFFFSNEHRQTVKEKNPEFKVGDIAKVLGKMWSECKDKSK 465
            V  TE   + S++WK +   EK+ Y    +  KK Y  EM  +                            P T  +KP+ KAK    +P KPK P++A F F+ E RQ ++++ P+    ++ + L +MW++  DK K
Sbjct:  313 VPSTERMMMCSQRWKLLKQHEKDAYQKRCEQRKKEYEIEMNRFLSSLSEEEQRRVLGEDKGGFKRGGRANSPAT--KKPASKAK---ANPEKPKRPISAMFIFAEEKRQKLQQERPDLSDSEVTRCLARMWNDLPDKKK 446

[Close]

BLAST of high mobility group-2 vs. Ensembl Medaka
Match: ubtf (upstream binding transcription factor [Source:NCBI gene;Acc:101156013])

HSP 1 Score: 54.299 bits (129), Expect = 2.676e-8
Identity = 34/128 (26.56%), Postives = 64/128 (50.00%), Query Frame = 1

Query:  130 VNFTEISKIASEKWKNISDKEKEKY-----NVL----------AQADKKRYTKEMEG-YEPETDNRKPSKKAKREAKDPNKPKAPLTAFFFFSNEHRQTVKEKNPEFKVGDIAKVLGKMWSECKDKSK 465
            V  TE   + S++WK +   EK+ Y     N+L          ++ +++R   E +G ++       P+ K      +P KPK P++A F F+ E RQ ++++ P+    ++ + L +MW++  DK K
Sbjct:  317 VPSTERMMMCSQRWKLLKQHEKDAYQKRCENILYLPFGPLQSLSEEEQRRVLGEDKGGFKRGGRANSPATKKPASKANPEKPKRPISAMFIFAEEKRQKLQQERPDLSDSEVTRCLARMWNDLPDKKK 444

HSP 2 Score: 46.9802 bits (110), Expect = 8.457e-6
Identity = 41/166 (24.70%), Postives = 82/166 (49.40%), Query Frame = 1

Query:   49 PSGAKSAYIIYTQAVREEYKKKNPDGKVNFTEISKIASEKWKNISDKEKEKYNVLAQADKKRYTKEMEGYEPETDNRKPSKKAKREAKDPNKPKAPLTAFFFFSNEHRQTVKEKNPEFKVGDIAKVLGKMWSECKDKSKYEEMNK--EAKEKYNLAMLEYKNGVPS 540
            P    + Y  +    R +Y K +P+  ++  +++KI S+K++ + DK+K+KY      DK+ +   M  +  E  +   +   K+ +  P KPK P   ++   N  ++   + +P+    DI   LGK W++  DK + + ++K  E ++ Y + +L   N  P+
Sbjct:  112 PKKPLTPYFRFFMEKRAKYAKLHPE--MSNLDLTKILSKKYRELPDKKKKKYVEDFLRDKETFVHSMSKFREEHPDLVETI-TKKGSNVPEKPKTPQQLWY---NHEKKAFLKTHPDATTKDIKDSLGKQWTQLPDKKRLKWISKSLEQQKAYEVRVLVVLNHSPA 271

[Close]

BLAST of high mobility group-2 vs. Planmine SMEST
Match: SMESG000020771.1 (SMESG000020771.1)

HSP 1 Score: 353.599 bits (906), Expect = 1.562e-125
Identity = 176/177 (99.44%), Postives = 176/177 (99.44%), Query Frame = 1

Query:   34 MNNKKPSGAKSAYIIYTQAVREEYKKKNPDGKVNFTEISKIASEKWKNISDKEKEKYNVLAQADKKRYTKEMEGYEPETDNRKPSKKAKREAKDPNKPKAPLTAFFFFSNEHRQTVKEKNPEFKVGDIAKVLGKMWSECKDKSKYEEMNKEAKEKYNLAMLEYKNGVPSAKKSKAHV 564
            MNNKKPSGAKSAYIIYTQAVREEYKKKNPDGKVNFTEISKIASEKWKNISDKEKEKYNVLAQADKKRYTKEMEGYEPETDNRKPSKKAKREAKDPNKPKAPLTAFFFFSNEHRQTVKEKNPEFKVGDIAKVLGKMWSECKDKSKYEEMNKEAKEKYNLAMLEYKNG PSAKKSKAHV
Sbjct:    1 MNNKKPSGAKSAYIIYTQAVREEYKKKNPDGKVNFTEISKIASEKWKNISDKEKEKYNVLAQADKKRYTKEMEGYEPETDNRKPSKKAKREAKDPNKPKAPLTAFFFFSNEHRQTVKEKNPEFKVGDIAKVLGKMWSECKDKSKYEEMNKEAKEKYNLAMLEYKNGAPSAKKSKAHV 177

[Close]

BLAST of high mobility group-2 vs. Planmine SMEST
Match: SMESG000068286.1 (SMESG000068286.1)

HSP 1 Score: 197.208 bits (500), Expect = 8.174e-64
Identity = 100/175 (57.14%), Postives = 128/175 (73.14%), Query Frame = 1

Query:   34 MNNKKPSGAKSAYIIYTQAVREEYKKKNPDGKVNFTEISKIASEKWKNISDKEKEKYNVLAQADKKRYTKEMEGYEPETDNRKPSKKAKREAKDPNKPKAPLTAFFFFSNEHRQTVKEKNPEFKVGDIAKVLGKMWSECKDKSKYEEMNKEAKEKYNLAMLEYKNGVPSAKKSKA 558
            M +KKP GAK+ Y  + Q VREE+KKK+PD ++ F+E SK  SEKWK +S KEK+++  +A  DK+RY KEM+ Y+P         K KR+ KDPNKPK   TAFFFFS+EHR+ +KE+NPE+KVGD+AKVLGKMW  CKDKSKYEE  K  KE+YN  + EYK+G P +KK+K 
Sbjct:    1 MVDKKPKGAKTPYACFVQVVREEHKKKHPDEQIVFSEFSKRCSEKWKEMSPKEKQRFMDIAAKDKERYLKEMDNYQPPAGT-----KNKRKIKDPNKPKGAWTAFFFFSDEHRKKIKEENPEYKVGDVAKVLGKMWEACKDKSKYEEQAKRDKERYNKELEEYKSGTPVSKKTKG 170

HSP 2 Score: 45.4394 bits (106), Expect = 8.133e-6
Identity = 30/84 (35.71%), Postives = 50/84 (59.52%), Query Frame = 1

Query:   46 KPSGAKSAYIIYTQAVREEYKKKNPDGKVNFTEISKIASEKWKNISDKEKEKYNVLAQADKKRYTKEMEGYEPETDNRKPSKKA 297
            KP GA +A+  ++   R++ K++NP+ KV   +++K+  + W+   DK K  Y   A+ DK+RY KE+E Y+  T   K +K A
Sbjct:   92 KPKGAWTAFFFFSDEHRKKIKEENPEYKVG--DVAKVLGKMWEACKDKSK--YEEQAKRDKERYNKELEEYKSGTPVSKKTKGA 171

[Close]

BLAST of high mobility group-2 vs. Planmine SMEST
Match: SMESG000012056.1 (SMESG000012056.1)

HSP 1 Score: 171.014 bits (432), Expect = 1.148e-53
Identity = 92/159 (57.86%), Postives = 113/159 (71.07%), Query Frame = 1

Query:   34 MNNKKPSGAKSAYIIYTQAVREEYKKKNPDGKVNFTEISKIASEKWKNISDKEKEKYNVLAQADKKRYTKEMEGYEP---ETDNRKPSKKAKREAKDPNKPKAPLTAFFFFSNEHRQTVKEKNPEFKVGDIAKVLGKMWSECKDKSKYEEMNKEAKEKY 501
            M NKKP+G+KSAY  + ++  E+YK +NPD K+N  EISK+ S+KWKN+S+ EK ++  LA  DKKRY  EME YEP   +    K  KK KR AKDPNKPK P+TAF FFSNE R +VKE NPEFK+GDIAK LG+ W EC +K KYE + K AK  Y
Sbjct:    1 MTNKKPTGSKSAYNCFMKSFIEKYKTENPDIKMNLGEISKLVSKKWKNLSEFEKNEFIELAAIDKKRYVDEMESYEPSEKDITKLKNKKKEKRAAKDPNKPKRPMTAFLFFSNEFRLSVKESNPEFKIGDIAKELGRKWKECIEKDKYENLAKSAKANY 159

[Close]

BLAST of high mobility group-2 vs. Planmine SMEST
Match: SMESG000012070.1 (SMESG000012070.1)

HSP 1 Score: 160.614 bits (405), Expect = 2.206e-49
Identity = 90/169 (53.25%), Postives = 121/169 (71.60%), Query Frame = 1

Query:   34 MNNKKPSGAKSAYIIYTQAVREEYKKKNPDGKVNFTEISKIASEKWKNISDKEKEKYNVLAQADKKRYTKEMEGYEPE------TDNRKPSKKAKREAKDPNKPKAPLTAFFFFSNEHRQTVKEKNPEFKVGDIAKVLGKMWSECKDKSKYEEMNKEAKEKYNLAMLEY 522
            M NKKPSG+KSAYI + Q+ RE+YK +NP+ K NF  ISK+ +E+WK +S+ +K+++N +A  DKKRY +EM  YEP+        ++K +K+AKR  +DPNKPK  ++AF  FSN+ R +VKE NPEFK+GD+AK LGKMW +  +K KYE M K AKEKY   M EY
Sbjct:    1 MTNKKPSGSKSAYICFQQSFREKYKTENPEIKPNFINISKLGAEEWKKLSESDKKEFNEMATIDKKRYAEEMANYEPDEKDVKDIKDKKKAKRAKRAKRDPNKPKRFMSAFILFSNDFRLSVKESNPEFKIGDVAKELGKMWKDYSEKDKYENMAKSAKEKYENEMREY 169

[Close]

BLAST of high mobility group-2 vs. Planmine SMEST
Match: SMESG000012065.1 (SMESG000012065.1)

HSP 1 Score: 160.614 bits (405), Expect = 2.206e-49
Identity = 90/169 (53.25%), Postives = 121/169 (71.60%), Query Frame = 1

Query:   34 MNNKKPSGAKSAYIIYTQAVREEYKKKNPDGKVNFTEISKIASEKWKNISDKEKEKYNVLAQADKKRYTKEMEGYEPE------TDNRKPSKKAKREAKDPNKPKAPLTAFFFFSNEHRQTVKEKNPEFKVGDIAKVLGKMWSECKDKSKYEEMNKEAKEKYNLAMLEY 522
            M NKKPSG+KSAYI + Q+ RE+YK +NP+ K NF  ISK+ +E+WK +S+ +K+++N +A  DKKRY +EM  YEP+        ++K +K+AKR  +DPNKPK  ++AF  FSN+ R +VKE NPEFK+GD+AK LGKMW +  +K KYE M K AKEKY   M EY
Sbjct:    1 MTNKKPSGSKSAYICFQQSFREKYKTENPEIKPNFINISKLGAEEWKKLSESDKKEFNEMATIDKKRYAEEMANYEPDEKDVKDIKDKKKAKRAKRAKRDPNKPKRFMSAFILFSNDFRLSVKESNPEFKIGDVAKELGKMWKDYSEKDKYENMAKSAKEKYENEMREY 169

The following BLAST results are available for this feature:

BLAST of high mobility group-2 vs. Ensembl Human
BLAST of high mobility group-2 vs. Ensembl Celegans
BLAST of high mobility group-2 vs. Ensembl Fly
BLAST of high mobility group-2 vs. Ensembl Zebrafish
BLAST of high mobility group-2 vs. Ensembl Xenopus
BLAST of high mobility group-2 vs. Ensembl Mouse
BLAST of high mobility group-2 vs. UniProt/SwissProt
BLAST of high mobility group-2 vs. TrEMBL
BLAST of high mobility group-2 vs. Ensembl Cavefish
BLAST of high mobility group-2 vs. Ensembl Sea Lamprey
BLAST of high mobility group-2 vs. Ensembl Yeast
BLAST of high mobility group-2 vs. Ensembl Nematostella
BLAST of high mobility group-2 vs. Ensembl Medaka
BLAST of high mobility group-2 vs. Planmine SMEST

BLAST of high mobility group-2 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
HMGB1	8.162e-38	48.51	high mobility group box 1 [Source:HGNC Symbol;Acc:...	[more]
HMGB1	8.162e-38	48.51	high mobility group box 1 [Source:HGNC Symbol;Acc:...	[more]
HMGB1	1.236e-37	44.83	high mobility group box 1 [Source:HGNC Symbol;Acc:...	[more]
HMGB1	1.236e-37	44.83	high mobility group box 1 [Source:HGNC Symbol;Acc:...	[more]
HMGB1	1.236e-37	44.83	high mobility group box 1 [Source:HGNC Symbol;Acc:...	[more]

BLAST of high mobility group-2 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5


Match Name	E-value	Identity	Description
hmg-1.2	1.586e-30	39.31	High mobility group protein 1.2 [Source:UniProtKB...	[more]
hmg-1.2	1.586e-30	39.31	High mobility group protein 1.2 [Source:UniProtKB...	[more]
hmg-1.2	9.780e-29	38.86	High mobility group protein 1.2 [Source:UniProtKB...	[more]
hmg-1.2	1.055e-28	38.86	High mobility group protein 1.2 [Source:UniProtKB...	[more]
hmg-1.2	1.055e-28	38.86	High mobility group protein 1.2 [Source:UniProtKB...	[more]

BLAST of high mobility group-2 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Dsp1	5.565e-40	45.45	gene:FBgn0278608 transcript:FBtr0089259	[more]
Dsp1	5.565e-40	45.45	gene:FBgn0278608 transcript:FBtr0089260	[more]
Dsp1	5.565e-40	45.45	gene:FBgn0278608 transcript:FBtr0089261	[more]
Dsp1	5.672e-40	45.45	gene:FBgn0278608 transcript:FBtr0089262	[more]
Dsp1	5.672e-40	45.45	gene:FBgn0278608 transcript:FBtr0339766	[more]

BLAST of high mobility group-2 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
hmgb2a	2.113e-39	45.93	high mobility group box 2a [Source:ZFIN;Acc:ZDB-GE...	[more]
hmgb2b	6.444e-39	42.11	high mobility group box 2b [Source:ZFIN;Acc:ZDB-GE...	[more]
hmgb2b	6.444e-39	42.11	high mobility group box 2b [Source:ZFIN;Acc:ZDB-GE...	[more]
hmgb2a	8.290e-39	48.05	high mobility group box 2a [Source:ZFIN;Acc:ZDB-GE...	[more]
hmgb3b	1.135e-35	45.00	high mobility group box 3b [Source:ZFIN;Acc:ZDB-GE...	[more]

BLAST of high mobility group-2 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5


Match Name	E-value	Identity	Description
hmgb2	3.881e-38	46.91	high mobility group box 2 [Source:NCBI gene;Acc:39...	[more]
cep170b	4.837e-38	45.45	centrosomal protein 170B [Source:Xenbase;Acc:XB-GE...	[more]
hmgb3	1.353e-34	45.22	high mobility group box 3 [Source:NCBI gene;Acc:44...	[more]
hmgb3	7.371e-34	46.62	high mobility group box 3 [Source:NCBI gene;Acc:44...	[more]
abcb6	2.960e-8	32.53	ATP binding cassette subfamily B member 6 (Langere...	[more]

BLAST of high mobility group-2 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Hmgb1	7.864e-38	45.35	high mobility group box 1 [Source:MGI Symbol;Acc:M...	[more]
Hmgb1	8.488e-38	44.83	high mobility group box 1 [Source:MGI Symbol;Acc:M...	[more]
Hmgb1	8.488e-38	44.83	high mobility group box 1 [Source:MGI Symbol;Acc:M...	[more]
Hmgb1	8.488e-38	44.83	high mobility group box 1 [Source:MGI Symbol;Acc:M...	[more]
Hmgb1	9.518e-38	48.51	high mobility group box 1 [Source:MGI Symbol;Acc:M...	[more]

BLAST of high mobility group-2 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|P26584\|HMGB2_CHICK	1.404e-39	46.30	High mobility group protein B2 OS=Gallus gallus OX...	[more]
sp\|Q24537\|HMG2_DROME	6.155e-39	45.45	High mobility group protein DSP1 OS=Drosophila mel...	[more]
sp\|P63159\|HMGB1_RAT	5.938e-37	44.83	High mobility group protein B1 OS=Rattus norvegicu...	[more]
sp\|B1MTB0\|HMGB1_PLEMO	5.938e-37	44.83	High mobility group protein B1 OS=Plecturocebus mo...	[more]
sp\|A9RA84\|HMGB1_PAPAN	5.938e-37	44.83	High mobility group protein B1 OS=Papio anubis OX=...	[more]

BLAST of high mobility group-2 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
I1ZIA1	5.615e-122	99.44	High mobility group-2 OS=Schmidtea mediterranea OX...	[more]
I1ZIJ2	2.939e-60	57.14	High mobility group-1 OS=Schmidtea mediterranea OX...	[more]
A0A5J4NYU2	3.115e-42	42.69	Uncharacterized protein OS=Paragonimus westermani ...	[more]
A0A2J7PFM2	4.043e-42	47.43	Uncharacterized protein OS=Cryptotermes secundus O...	[more]
A0A4S2M7M8	8.882e-42	44.17	Uncharacterized protein OS=Opisthorchis felineus O...	[more]

BLAST of high mobility group-2 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
hmgb2a	1.953e-37	45.14	high mobility group box 2 [Source:NCBI gene;Acc:11...	[more]
hmgb1a	8.546e-37	45.12	high mobility group-T protein-like [Source:NCBI ge...	[more]
ENSAMXT00000044228.1	4.453e-36	42.69	high mobility group protein B2-like [Source:NCBI g...	[more]
hmgb1b	1.323e-35	47.01	high mobility group protein B1-like [Source:NCBI g...	[more]
hmgb3a	2.523e-31	39.63	high mobility group protein B3 [Source:NCBI gene;A...	[more]

BLAST of high mobility group-2 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 4


Match Name	E-value	Identity	Description
hmgb2b	8.629e-38	43.95	high mobility group box 2b [Source:ZFIN;Acc:ZDB-GE...	[more]
hmgb2a	1.345e-37	48.12	high mobility group box 2a [Source:ZFIN;Acc:ZDB-GE...	[more]
ENSPMAT00000005794.1	1.613e-7	27.27	pep scaffold:Pmarinus_7.0:GL478246:10745:21158:-1 ...	[more]
smarce1	9.640e-6	34.25	SWI/SNF related, matrix associated, actin dependen...	[more]

BLAST of high mobility group-2 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 4


Match Name	E-value	Identity	Description
NHP6B	5.946e-13	37.33	High-mobility group (HMG) protein; binds to and re...	[more]
ABF2	9.770e-13	32.47	Mitochondrial DNA-binding protein; involved in mit...	[more]
IXR1	3.294e-11	28.67	Transcriptional repressor that regulates hypoxic g...	[more]
NHP6A	1.556e-10	38.96	High-mobility group (HMG) protein; binds to and re...	[more]

BLAST of high mobility group-2 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5


Match Name	E-value	Identity	Description
EDO36028	1.055e-33	42.20	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO39305	5.684e-12	42.42	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO41032	1.852e-11	37.80	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO47230	5.524e-10	34.15	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO40495	5.520e-7	37.50	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of high mobility group-2 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5


Match Name	E-value	Identity	Description
hmgb2a	1.891e-38	45.29	high mobility group protein B2 [Source:NCBI gene;A...	[more]
hmgb1b	1.025e-35	43.37	high mobility group protein B1 [Source:NCBI gene;A...	[more]
hmgb1a	7.030e-35	45.40	high mobility group-T protein [Source:NCBI gene;Ac...	[more]
ubtf	3.149e-9	28.06	upstream binding transcription factor [Source:NCBI...	[more]
ubtf	2.676e-8	26.56	upstream binding transcription factor [Source:NCBI...	[more]

BLAST of high mobility group-2 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5


Match Name	E-value	Identity	Description
SMESG000020771.1	1.562e-125	99.44	SMESG000020771.1	[more]
SMESG000068286.1	8.174e-64	57.14	SMESG000068286.1	[more]
SMESG000012056.1	1.148e-53	57.86	SMESG000012056.1	[more]
SMESG000012070.1	2.206e-49	53.25	SMESG000012070.1	[more]
SMESG000012065.1	2.206e-49	53.25	SMESG000012065.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Cross References

External references for this transcript


Database	Accession
SmedGD GBrowse	SMED30027770
GenBank	AFJ24755.1

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30027770 ID=SMED30027770|Name=high mobility group-2|organism=Schmidtea mediterranea sexual|type=transcript|length=686bp
AATTTTTAAGGTTATAATTTAGTGACAAAGTCAATGAACAACAAAAAGCC
ATCTGGAGCCAAGTCGGCTTATATTATTTATACACAAGCAGTAAGAGAGG
AATACAAAAAGAAAAATCCCGATGGCAAAGTAAATTTTACAGAAATTTCT
AAAATTGCATCCGAGAAATGGAAGAACATTTCCGATAAAGAAAAGGAAAA
ATATAATGTTTTGGCTCAAGCTGATAAAAAGAGATACACGAAAGAAATGG
AAGGTTATGAGCCCGAAACCGACAATAGGAAGCCTTCAAAAAAAGCTAAA
CGCGAAGCTAAGGATCCTAATAAGCCGAAGGCTCCTTTGACTGCATTTTT
TTTCTTTTCAAATGAACACCGACAAACAGTTAAGGAAAAGAATCCTGAAT
TTAAAGTCGGTGATATTGCAAAAGTTTTGGGTAAAATGTGGAGTGAATGC
AAGGATAAATCTAAGTACGAAGAAATGAACAAAGAGGCTAAAGAGAAATA
TAATTTGGCAATGCTAGAGTACAAAAATGGAGTTCCATCTGCCAAGAAAT
CTAAAGCTCATGTCAGTGATGAAGGAGATGAGGAAGAATATGAAAGCGAA
GAAGAAGAATAAACTGCTGTCATGAGATTTAGTAAAGCACAAACTTTTTG
TGCTATTATCAAATAAATTTGCATTTATGTGTTTTT

protein sequence of SMED30027770-orf-1

>SMED30027770-orf-1 ID=SMED30027770-orf-1|Name=SMED30027770-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=193bp
MNNKKPSGAKSAYIIYTQAVREEYKKKNPDGKVNFTEISKIASEKWKNIS
DKEKEKYNVLAQADKKRYTKEMEGYEPETDNRKPSKKAKREAKDPNKPKA
PLTAFFFFSNEHRQTVKEKNPEFKVGDIAKVLGKMWSECKDKSKYEEMNK
EAKEKYNLAMLEYKNGVPSAKKSKAHVSDEGDEEEYESEEEE*

Aliases

The feature 'high mobility group-2' has the following synonyms


Synonym
hmg-2

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000014	zeta neoblast
PLANA:0000099	neuron
PLANA:0000429	neoblast
PLANA:0002013	Category 1 cell
PLANA:0002109	X1 cell

Vocabulary: **INTERPRO**
Term	Definition
IPR036910	HMG_box_dom_sf
IPR009071	HMG_box_dom

Vocabulary: **molecular function**
Term	Definition
GO:0003677	DNA binding

Vocabulary: **cellular component**
Term	Definition
GO:0005634	nucleus

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
None	No IPR available	COILS	Coil	Coil	coord: 142..162
None	No IPR available	COILS	Coil	Coil	coord: 189..192
None	No IPR available	PRINTS	PR00886	HIGHMOBLTY12	coord: 131..150 score: 32.96 coord: 113..131 score: 41.91 coord: 37..59 score: 48.95
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 68..98
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 68..97
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 165..192
None	No IPR available	PANTHER	PTHR13711:SF302	HIGH MOBILITY GROUP PROTEIN DSP1-RELATED	coord: 80..188
None	No IPR available	PANTHER	PTHR13711	SWI/SNF-RELATED CHROMATIN BINDING PROTEIN	coord: 80..188
None	No IPR available	PANTHER	PTHR13711	SWI/SNF-RELATED CHROMATIN BINDING PROTEIN	coord: 5..87
None	No IPR available	PANTHER	PTHR13711:SF302	HIGH MOBILITY GROUP PROTEIN DSP1-RELATED	coord: 5..87
None	No IPR available	CDD	cd01390	HMGB-UBF_HMG-box	coord: 6..73 e-value: 2.44283E-14 score: 62.6453
None	No IPR available	CDD	cd01390	HMGB-UBF_HMG-box	coord: 98..160 e-value: 9.07255E-14 score: 61.1045
IPR009071	High mobility group box domain	SMART	SM00398	hmgende2	coord: 97..165 e-value: 2.5E-21 score: 86.9 coord: 5..77 e-value: 1.9E-22 score: 90.5
IPR009071	High mobility group box domain	PFAM	PF09011	HMG_box_2	coord: 4..75 e-value: 1.4E-19 score: 70.4
IPR009071	High mobility group box domain	PFAM	PF00505	HMG_box	coord: 98..164 e-value: 1.8E-18 score: 66.7
IPR009071	High mobility group box domain	PROSITE	PS50118	HMG_BOX_2	coord: 98..164 score: 16.865
IPR009071	High mobility group box domain	PROSITE	PS50118	HMG_BOX_2	coord: 6..76 score: 18.034
IPR036910	High mobility group box domain superfamily	GENE3D	G3DSA:1.10.30.10		coord: 1..77 e-value: 1.4E-25 score: 91.4
IPR036910	High mobility group box domain superfamily	GENE3D	G3DSA:1.10.30.10		coord: 91..165 e-value: 9.3E-23 score: 82.5
IPR036910	High mobility group box domain superfamily	SUPERFAMILY	SSF47095	HMG-box	coord: 89..168
IPR036910	High mobility group box domain superfamily	SUPERFAMILY	SSF47095	HMG-box	coord: 2..78