NAD-dependent protein deacetylase
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30027733 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 7
Homology
BLAST of NAD-dependent protein deacetylase vs. Ensembl Human
Match: SIRT3 (sirtuin 3 [Source:HGNC Symbol;Acc:HGNC:14931]) HSP 1 Score: 191.045 bits (484), Expect = 2.209e-53 Identity = 93/168 (55.36%), Postives = 116/168 (69.05%), Query Frame = 2
Query: 290 SGTDDQKFIVDICQKILTSKIKNIVIMAGAGISCPSGIPDFRSPGTGLYDNLKQYKIPYPEAIFDIDYFLQNPKPFFALAKELFPSGKYRPNKVHYFFRLLQEKKLLRRVYTQNIDGLERLAGLNDTNLVEAHGTFASASCVRC-----GEDYSATQLKLKHSISEIC 778
G DD D+ + I + +V+M GAGIS PSGIPDFRSPG+GLY NL+QY +PYPEAIF++ +F NPKPFF LAKEL+P G Y+PN HYF RLL +K LL R+YTQNIDGLER++G+ + LVEAHGTFASA+C C GED A + + +C
Sbjct: 41 GGRDD-----DVAELIRARACQRVVVMVGAGISTPSGIPDFRSPGSGLYSNLQQYDLPYPEAIFELPFFFHNPKPFFTLAKELYP-GNYKPNVTHYFLRLLHDKGLLLRLYTQNIDGLERVSGIPASKLVEAHGTFASATCTVCQRPFPGEDIRADVMADRVPRCPVC 202 HSP 2 Score: 96.6709 bits (239), Expect = 6.004e-21 Identity = 52/99 (52.53%), Postives = 61/99 (61.62%), Query Frame = 2
Query: 1106 CSKCRGIVKPDIVFFGEDLPSKFHLFRSDFQQADLLLVMGTSLEVEPFASIVDSTRFGTPRVLINRQPVGVFRSKRRVHDNCVLGKQT----SVSELAG 1390
C C G+VKPDIVFFGE LP +F L DF ADLLL++GTSLEVEPFAS+ ++ R PR+LINR VG R D LG S+ EL G
Sbjct: 199 CPVCTGVVKPDIVFFGEPLPQRFLLHVVDFPMADLLLILGTSLEVEPFASLTEAVRSSVPRLLINRDLVGPLAWHPRSRDVAQLGDVVHGVESLVELLG 297
BLAST of NAD-dependent protein deacetylase vs. Ensembl Human
Match: SIRT3 (sirtuin 3 [Source:HGNC Symbol;Acc:HGNC:14931]) HSP 1 Score: 191.045 bits (484), Expect = 5.248e-53 Identity = 85/146 (58.22%), Postives = 110/146 (75.34%), Query Frame = 2
Query: 320 DICQKILTSKIKNIVIMAGAGISCPSGIPDFRSPGTGLYDNLKQYKIPYPEAIFDIDYFLQNPKPFFALAKELFPSGKYRPNKVHYFFRLLQEKKLLRRVYTQNIDGLERLAGLNDTNLVEAHGTFASASCVRCGEDYSATQLKLK 757
D+ + I + +V+M GAGIS PSGIPDFRSPG+GLY NL+QY +PYPEAIF++ +F NPKPFF LAKEL+P G Y+PN HYF RLL +K LL R+YTQNIDGLER++G+ + LVEAHGTFASA+C C + ++++
Sbjct: 127 DVAELIRARACQRVVVMVGAGISTPSGIPDFRSPGSGLYSNLQQYDLPYPEAIFELPFFFHNPKPFFTLAKELYP-GNYKPNVTHYFLRLLHDKGLLLRLYTQNIDGLERVSGIPASKLVEAHGTFASATCTVCQRPFPGEDIRVE 271
BLAST of NAD-dependent protein deacetylase vs. Ensembl Human
Match: SIRT3 (sirtuin 3 [Source:HGNC Symbol;Acc:HGNC:14931]) HSP 1 Score: 191.045 bits (484), Expect = 1.919e-52 Identity = 90/158 (56.96%), Postives = 113/158 (71.52%), Query Frame = 2
Query: 320 DICQKILTSKIKNIVIMAGAGISCPSGIPDFRSPGTGLYDNLKQYKIPYPEAIFDIDYFLQNPKPFFALAKELFPSGKYRPNKVHYFFRLLQEKKLLRRVYTQNIDGLERLAGLNDTNLVEAHGTFASASCVRC-----GEDYSATQLKLKHSISEIC 778
D+ + I + +V+M GAGIS PSGIPDFRSPG+GLY NL+QY +PYPEAIF++ +F NPKPFF LAKEL+P G Y+PN HYF RLL +K LL R+YTQNIDGLER++G+ + LVEAHGTFASA+C C GED A + + +C
Sbjct: 127 DVAELIRARACQRVVVMVGAGISTPSGIPDFRSPGSGLYSNLQQYDLPYPEAIFELPFFFHNPKPFFTLAKELYP-GNYKPNVTHYFLRLLHDKGLLLRLYTQNIDGLERVSGIPASKLVEAHGTFASATCTVCQRPFPGEDIRADVMADRVPRCPVC 283 HSP 2 Score: 96.2857 bits (238), Expect = 2.396e-20 Identity = 48/85 (56.47%), Postives = 56/85 (65.88%), Query Frame = 2
Query: 1106 CSKCRGIVKPDIVFFGEDLPSKFHLFRSDFQQADLLLVMGTSLEVEPFASIVDSTRFGTPRVLINRQPVGVFRSKRRVHDNCVLG 1360
C C G+VKPDIVFFGE LP +F L DF ADLLL++GTSLEVEPFAS+ ++ R PR+LINR VG R D LG
Sbjct: 280 CPVCTGVVKPDIVFFGEPLPQRFLLHVVDFPMADLLLILGTSLEVEPFASLTEAVRSSVPRLLINRDLVGPLAWHPRSRDVAQLG 364
BLAST of NAD-dependent protein deacetylase vs. Ensembl Human
Match: SIRT3 (sirtuin 3 [Source:HGNC Symbol;Acc:HGNC:14931]) HSP 1 Score: 182.57 bits (462), Expect = 3.026e-51 Identity = 87/142 (61.27%), Postives = 105/142 (73.94%), Query Frame = 2
Query: 368 MAGAGISCPSGIPDFRSPGTGLYDNLKQYKIPYPEAIFDIDYFLQNPKPFFALAKELFPSGKYRPNKVHYFFRLLQEKKLLRRVYTQNIDGLERLAGLNDTNLVEAHGTFASASCVRC-----GEDYSATQLKLKHSISEIC 778
M GAGIS PSGIPDFRSPG+GLY NL+QY +PYPEAIF++ +F NPKPFF LAKEL+P G Y+PN HYF RLL +K LL R+YTQNIDGLER++G+ + LVEAHGTFASA+C C GED A + + +C
Sbjct: 1 MVGAGISTPSGIPDFRSPGSGLYSNLQQYDLPYPEAIFELPFFFHNPKPFFTLAKELYP-GNYKPNVTHYFLRLLHDKGLLLRLYTQNIDGLERVSGIPASKLVEAHGTFASATCTVCQRPFPGEDIRADVMADRVPRCPVC 141 HSP 2 Score: 97.4413 bits (241), Expect = 9.497e-22 Identity = 52/99 (52.53%), Postives = 61/99 (61.62%), Query Frame = 2
Query: 1106 CSKCRGIVKPDIVFFGEDLPSKFHLFRSDFQQADLLLVMGTSLEVEPFASIVDSTRFGTPRVLINRQPVGVFRSKRRVHDNCVLGKQT----SVSELAG 1390
C C G+VKPDIVFFGE LP +F L DF ADLLL++GTSLEVEPFAS+ ++ R PR+LINR VG R D LG S+ EL G
Sbjct: 138 CPVCTGVVKPDIVFFGEPLPQRFLLHVVDFPMADLLLILGTSLEVEPFASLTEAVRSSVPRLLINRDLVGPLAWHPRSRDVAQLGDVVHGVESLVELLG 236
BLAST of NAD-dependent protein deacetylase vs. Ensembl Human
Match: SIRT2 (sirtuin 2 [Source:HGNC Symbol;Acc:HGNC:10886]) HSP 1 Score: 176.792 bits (447), Expect = 1.639e-49 Identity = 87/176 (49.43%), Postives = 123/176 (69.89%), Query Frame = 2
Query: 245 MIYLSSTFGRYLSTPSGTD---DQKFIVDICQKILTSKIKNIVIMAGAGISCPSGIPDFRSPGTGLYDNLKQYKIPYPEAIFDIDYFLQNPKPFFALAKELFPSGKYRPNKVHYFFRLLQEKKLLRRVYTQNIDGLERLAGLNDTNLVEAHGTFASASCV--RCGEDYSATQLKLK 757
M +L + F + LS S + D+ + + + + + + + ++ + GAGIS +GIPDFRSP TGLYDNL++Y +PYPEAIF+I YF ++P+PFFALAKEL+P G+++P HYF RLL++K LL R YTQNID LER+AGL +LVEAHGTF ++ CV C +Y + +K K
Sbjct: 1 MDFLRNLFSQTLSLGSQKERLLDELTLEGVARYMQSERCRRVICLVGAGISTSAGIPDFRSPSTGLYDNLEKYHLPYPEAIFEISYFKKHPEPFFALAKELYP-GQFKPTICHYFMRLLKDKGLLLRCYTQNIDTLERIAGLEQEDLVEAHGTFYTSHCVSASCRHEYPLSWMKEK 175 HSP 2 Score: 60.4622 bits (145), Expect = 2.548e-9 Identity = 28/45 (62.22%), Postives = 35/45 (77.78%), Query Frame = 2
Query: 1106 CSKCRGIVKPDIVFFGEDLPSK-FHLFRSDFQQADLLLVMGTSLE 1237
C C+ +VKPDIVFFGE LP++ F +SDF + DLLLVMGTSL+
Sbjct: 184 CEDCQSLVKPDIVFFGESLPARFFSCMQSDFLKVDLLLVMGTSLQ 228
BLAST of NAD-dependent protein deacetylase vs. Ensembl Celegans
Match: sir-2.1 (NAD-dependent protein deacetylase sir-2.1 [Source:UniProtKB/Swiss-Prot;Acc:Q21921]) HSP 1 Score: 119.398 bits (298), Expect = 1.420e-27 Identity = 58/135 (42.96%), Postives = 85/135 (62.96%), Query Frame = 2
Query: 353 KNIVIMAGAGISCPSGIPDFRSPGTGLYDNLKQY--KIPYPEAIFDIDYFLQNPKPFFALAKELFPSGKYRPNKVHYFFRLLQEKKLLRRVYTQNIDGLERLAGLNDTNLVEAHGTFASASCVRCGEDYSATQLK 751
K+I+++ GAG+S GIPDFRS G+Y L+ +P P A+FDI YF +NP PF+ A+E+FP G++ P+ H F + L+ L R YTQNID LE G+ +VE HG+F+ +C RCG+ Y +++
Sbjct: 116 KHILVLTGAGVSVSCGIPDFRSKD-GIYARLRSEFPDLPDPTAMFDIRYFRENPAPFYNFAREIFP-GQFVPSVSHRFIKELETSGRLLRNYTQNIDTLEHQTGIK--RVVECHGSFSKCTCTRCGQKYDGNEIR 246 HSP 2 Score: 71.633 bits (174), Expect = 1.588e-12 Identity = 41/120 (34.17%), Postives = 66/120 (55.00%), Query Frame = 2
Query: 998 IINC-GSLSKNSLSNISGPKASLIIYLESIDKSEICYCSKCRGIVKPDIVFFGEDLPSKFHL-FRSDFQQADLLLVMGTSLEVEPFASIVDSTRFGTPRVLINRQPVGVFRSKRRVHDNC 1351
++ C GS SK + + G K E + + +C +C G++KP+IVFFGEDL +FH D + DL++V+G+SL+V P A I P++LINR+ + + + + NC
Sbjct: 221 VVECHGSFSKCTCTRC-GQKYDGNEIREEVLAMRVAHCKRCEGVIKPNIVFFGEDLGREFHQHVTEDKHKVDLIVVIGSSLKVRPVALIPHCVDKNVPQILINRESLPHYNADIELLGNC 339
BLAST of NAD-dependent protein deacetylase vs. Ensembl Celegans
Match: sir-2.1 (NAD-dependent protein deacetylase sir-2.1 [Source:UniProtKB/Swiss-Prot;Acc:Q21921]) HSP 1 Score: 119.398 bits (298), Expect = 1.420e-27 Identity = 58/135 (42.96%), Postives = 85/135 (62.96%), Query Frame = 2
Query: 353 KNIVIMAGAGISCPSGIPDFRSPGTGLYDNLKQY--KIPYPEAIFDIDYFLQNPKPFFALAKELFPSGKYRPNKVHYFFRLLQEKKLLRRVYTQNIDGLERLAGLNDTNLVEAHGTFASASCVRCGEDYSATQLK 751
K+I+++ GAG+S GIPDFRS G+Y L+ +P P A+FDI YF +NP PF+ A+E+FP G++ P+ H F + L+ L R YTQNID LE G+ +VE HG+F+ +C RCG+ Y +++
Sbjct: 116 KHILVLTGAGVSVSCGIPDFRSKD-GIYARLRSEFPDLPDPTAMFDIRYFRENPAPFYNFAREIFP-GQFVPSVSHRFIKELETSGRLLRNYTQNIDTLEHQTGIK--RVVECHGSFSKCTCTRCGQKYDGNEIR 246 HSP 2 Score: 71.633 bits (174), Expect = 1.588e-12 Identity = 41/120 (34.17%), Postives = 66/120 (55.00%), Query Frame = 2
Query: 998 IINC-GSLSKNSLSNISGPKASLIIYLESIDKSEICYCSKCRGIVKPDIVFFGEDLPSKFHL-FRSDFQQADLLLVMGTSLEVEPFASIVDSTRFGTPRVLINRQPVGVFRSKRRVHDNC 1351
++ C GS SK + + G K E + + +C +C G++KP+IVFFGEDL +FH D + DL++V+G+SL+V P A I P++LINR+ + + + + NC
Sbjct: 221 VVECHGSFSKCTCTRC-GQKYDGNEIREEVLAMRVAHCKRCEGVIKPNIVFFGEDLGREFHQHVTEDKHKVDLIVVIGSSLKVRPVALIPHCVDKNVPQILINRESLPHYNADIELLGNC 339
BLAST of NAD-dependent protein deacetylase vs. Ensembl Celegans
Match: sir-2.1 (NAD-dependent protein deacetylase sir-2.1 [Source:UniProtKB/Swiss-Prot;Acc:Q21921]) HSP 1 Score: 119.398 bits (298), Expect = 1.420e-27 Identity = 58/135 (42.96%), Postives = 85/135 (62.96%), Query Frame = 2
Query: 353 KNIVIMAGAGISCPSGIPDFRSPGTGLYDNLKQY--KIPYPEAIFDIDYFLQNPKPFFALAKELFPSGKYRPNKVHYFFRLLQEKKLLRRVYTQNIDGLERLAGLNDTNLVEAHGTFASASCVRCGEDYSATQLK 751
K+I+++ GAG+S GIPDFRS G+Y L+ +P P A+FDI YF +NP PF+ A+E+FP G++ P+ H F + L+ L R YTQNID LE G+ +VE HG+F+ +C RCG+ Y +++
Sbjct: 116 KHILVLTGAGVSVSCGIPDFRSKD-GIYARLRSEFPDLPDPTAMFDIRYFRENPAPFYNFAREIFP-GQFVPSVSHRFIKELETSGRLLRNYTQNIDTLEHQTGIK--RVVECHGSFSKCTCTRCGQKYDGNEIR 246 HSP 2 Score: 71.633 bits (174), Expect = 1.588e-12 Identity = 41/120 (34.17%), Postives = 66/120 (55.00%), Query Frame = 2
Query: 998 IINC-GSLSKNSLSNISGPKASLIIYLESIDKSEICYCSKCRGIVKPDIVFFGEDLPSKFHL-FRSDFQQADLLLVMGTSLEVEPFASIVDSTRFGTPRVLINRQPVGVFRSKRRVHDNC 1351
++ C GS SK + + G K E + + +C +C G++KP+IVFFGEDL +FH D + DL++V+G+SL+V P A I P++LINR+ + + + + NC
Sbjct: 221 VVECHGSFSKCTCTRC-GQKYDGNEIREEVLAMRVAHCKRCEGVIKPNIVFFGEDLGREFHQHVTEDKHKVDLIVVIGSSLKVRPVALIPHCVDKNVPQILINRESLPHYNADIELLGNC 339
BLAST of NAD-dependent protein deacetylase vs. Ensembl Celegans
Match: sir-2.1 (NAD-dependent protein deacetylase sir-2.1 [Source:UniProtKB/Swiss-Prot;Acc:Q21921]) HSP 1 Score: 119.398 bits (298), Expect = 1.534e-27 Identity = 58/135 (42.96%), Postives = 85/135 (62.96%), Query Frame = 2
Query: 353 KNIVIMAGAGISCPSGIPDFRSPGTGLYDNLKQY--KIPYPEAIFDIDYFLQNPKPFFALAKELFPSGKYRPNKVHYFFRLLQEKKLLRRVYTQNIDGLERLAGLNDTNLVEAHGTFASASCVRCGEDYSATQLK 751
K+I+++ GAG+S GIPDFRS G+Y L+ +P P A+FDI YF +NP PF+ A+E+FP G++ P+ H F + L+ L R YTQNID LE G+ +VE HG+F+ +C RCG+ Y +++
Sbjct: 146 KHILVLTGAGVSVSCGIPDFRSKD-GIYARLRSEFPDLPDPTAMFDIRYFRENPAPFYNFAREIFP-GQFVPSVSHRFIKELETSGRLLRNYTQNIDTLEHQTGIK--RVVECHGSFSKCTCTRCGQKYDGNEIR 276 HSP 2 Score: 71.633 bits (174), Expect = 1.699e-12 Identity = 41/120 (34.17%), Postives = 66/120 (55.00%), Query Frame = 2
Query: 998 IINC-GSLSKNSLSNISGPKASLIIYLESIDKSEICYCSKCRGIVKPDIVFFGEDLPSKFHL-FRSDFQQADLLLVMGTSLEVEPFASIVDSTRFGTPRVLINRQPVGVFRSKRRVHDNC 1351
++ C GS SK + + G K E + + +C +C G++KP+IVFFGEDL +FH D + DL++V+G+SL+V P A I P++LINR+ + + + + NC
Sbjct: 251 VVECHGSFSKCTCTRC-GQKYDGNEIREEVLAMRVAHCKRCEGVIKPNIVFFGEDLGREFHQHVTEDKHKVDLIVVIGSSLKVRPVALIPHCVDKNVPQILINRESLPHYNADIELLGNC 369
BLAST of NAD-dependent protein deacetylase vs. Ensembl Celegans
Match: sir-2.1 (NAD-dependent protein deacetylase sir-2.1 [Source:UniProtKB/Swiss-Prot;Acc:Q21921]) HSP 1 Score: 119.398 bits (298), Expect = 1.534e-27 Identity = 58/135 (42.96%), Postives = 85/135 (62.96%), Query Frame = 2
Query: 353 KNIVIMAGAGISCPSGIPDFRSPGTGLYDNLKQY--KIPYPEAIFDIDYFLQNPKPFFALAKELFPSGKYRPNKVHYFFRLLQEKKLLRRVYTQNIDGLERLAGLNDTNLVEAHGTFASASCVRCGEDYSATQLK 751
K+I+++ GAG+S GIPDFRS G+Y L+ +P P A+FDI YF +NP PF+ A+E+FP G++ P+ H F + L+ L R YTQNID LE G+ +VE HG+F+ +C RCG+ Y +++
Sbjct: 146 KHILVLTGAGVSVSCGIPDFRSKD-GIYARLRSEFPDLPDPTAMFDIRYFRENPAPFYNFAREIFP-GQFVPSVSHRFIKELETSGRLLRNYTQNIDTLEHQTGIK--RVVECHGSFSKCTCTRCGQKYDGNEIR 276 HSP 2 Score: 71.633 bits (174), Expect = 1.699e-12 Identity = 41/120 (34.17%), Postives = 66/120 (55.00%), Query Frame = 2
Query: 998 IINC-GSLSKNSLSNISGPKASLIIYLESIDKSEICYCSKCRGIVKPDIVFFGEDLPSKFHL-FRSDFQQADLLLVMGTSLEVEPFASIVDSTRFGTPRVLINRQPVGVFRSKRRVHDNC 1351
++ C GS SK + + G K E + + +C +C G++KP+IVFFGEDL +FH D + DL++V+G+SL+V P A I P++LINR+ + + + + NC
Sbjct: 251 VVECHGSFSKCTCTRC-GQKYDGNEIREEVLAMRVAHCKRCEGVIKPNIVFFGEDLGREFHQHVTEDKHKVDLIVVIGSSLKVRPVALIPHCVDKNVPQILINRESLPHYNADIELLGNC 369
BLAST of NAD-dependent protein deacetylase vs. Ensembl Fly
Match: Sirt2 (gene:FBgn0038788 transcript:FBtr0083882) HSP 1 Score: 171.014 bits (432), Expect = 2.651e-46 Identity = 77/133 (57.89%), Postives = 101/133 (75.94%), Query Frame = 2
Query: 353 KNIVIMAGAGISCPSGIPDFRSPGTGLYDNLKQYKIPYPEAIFDIDYFLQNPKPFFALAKELFPSGKYRPNKVHYFFRLLQEKKLLRRVYTQNIDGLERLAGLNDTNLVEAHGTFASASCVRCGEDYSATQLK 751
+ IV M GAGIS +GIPDFRSPG+GLY NLK+Y++P+P AIFD+DYF +NP PFFALAKEL+P G + P HYF RLL +K LL+R YTQNID L+RL GL + ++EAHG+F + C++C ++Y +K
Sbjct: 48 RKIVTMVGAGISTSAGIPDFRSPGSGLYSNLKKYELPHPTAIFDLDYFEKNPAPFFALAKELYP-GSFIPTPAHYFIRLLNDKGLLQRHYTQNIDTLDRLTGLPEDKIIEAHGSFHTNHCIKCRKEYDMDWMK 179 HSP 2 Score: 84.7297 bits (208), Expect = 4.001e-17 Identity = 42/71 (59.15%), Postives = 52/71 (73.24%), Query Frame = 2
Query: 1106 CSKCRGIVKPDIVFFGEDLPSKFHLF-RSDFQQADLLLVMGTSLEVEPFASIVDSTRFGTPRVLINRQPVG 1315
C KC+G+VKPDIVFFGE+LP +F+ DFQ DLL++MGTSLEV+PFAS+V R+LINR VG
Sbjct: 190 CQKCQGVVKPDIVFFGENLPKRFYSSPEEDFQDCDLLIIMGTSLEVQPFASLVWRPGPRCIRLLINRDAVG 260
BLAST of NAD-dependent protein deacetylase vs. Ensembl Fly
Match: Sirt2 (gene:FBgn0038788 transcript:FBtr0344243) HSP 1 Score: 171.014 bits (432), Expect = 2.651e-46 Identity = 77/133 (57.89%), Postives = 101/133 (75.94%), Query Frame = 2
Query: 353 KNIVIMAGAGISCPSGIPDFRSPGTGLYDNLKQYKIPYPEAIFDIDYFLQNPKPFFALAKELFPSGKYRPNKVHYFFRLLQEKKLLRRVYTQNIDGLERLAGLNDTNLVEAHGTFASASCVRCGEDYSATQLK 751
+ IV M GAGIS +GIPDFRSPG+GLY NLK+Y++P+P AIFD+DYF +NP PFFALAKEL+P G + P HYF RLL +K LL+R YTQNID L+RL GL + ++EAHG+F + C++C ++Y +K
Sbjct: 48 RKIVTMVGAGISTSAGIPDFRSPGSGLYSNLKKYELPHPTAIFDLDYFEKNPAPFFALAKELYP-GSFIPTPAHYFIRLLNDKGLLQRHYTQNIDTLDRLTGLPEDKIIEAHGSFHTNHCIKCRKEYDMDWMK 179 HSP 2 Score: 84.7297 bits (208), Expect = 4.001e-17 Identity = 42/71 (59.15%), Postives = 52/71 (73.24%), Query Frame = 2
Query: 1106 CSKCRGIVKPDIVFFGEDLPSKFHLF-RSDFQQADLLLVMGTSLEVEPFASIVDSTRFGTPRVLINRQPVG 1315
C KC+G+VKPDIVFFGE+LP +F+ DFQ DLL++MGTSLEV+PFAS+V R+LINR VG
Sbjct: 190 CQKCQGVVKPDIVFFGENLPKRFYSSPEEDFQDCDLLIIMGTSLEVQPFASLVWRPGPRCIRLLINRDAVG 260
BLAST of NAD-dependent protein deacetylase vs. Ensembl Fly
Match: Sirt1 (gene:FBgn0024291 transcript:FBtr0080434) HSP 1 Score: 124.02 bits (310), Expect = 1.920e-28 Identity = 58/130 (44.62%), Postives = 90/130 (69.23%), Query Frame = 2
Query: 338 LTSKIKNIVIMAGAGISCPSGIPDFRSPGTGLYDNLKQY--KIPYPEAIFDIDYFLQNPKPFFALAKELFPSGKYRPNKVHYFFRLLQEKKLLRRVYTQNIDGLERLAGLNDTNLVEAHGTFASASCVRC 721
L K + I+++ GAG+S GIPDFRS G+Y L +P P+A+FDI+YF ++P+PF+ A+E++P G+++P+ H F ++L+ K L R YTQNID LER+AG+ ++E HG+F++ASC +C
Sbjct: 217 LVKKSQKIIVLTGAGVSVSCGIPDFRS-TNGIYARLAHDFPDLPDPQAMFDINYFKRDPRPFYKFAREIYP-GEFQPSPCHRFIKMLETKGKLLRNYTQNIDTLERVAGIQ--RVIECHGSFSTASCTKC 342 HSP 2 Score: 65.4698 bits (158), Expect = 2.515e-10 Identity = 32/63 (50.79%), Postives = 44/63 (69.84%), Query Frame = 2
Query: 1121 GIVKPDIVFFGEDLPSKFH-LFRSDFQQADLLLVMGTSLEVEPFASIVDSTRFGTPRVLINRQ 1306
GI+KPDIVFFGE LP ++H + +D DLL+V+G+SL+V P A I S P++LINR+
Sbjct: 392 GIMKPDIVFFGEGLPDEYHTVMATDKDVCDLLIVIGSSLKVRPVAHIPSSIPATVPQILINRE 454
BLAST of NAD-dependent protein deacetylase vs. Ensembl Fly
Match: Sirt6 (gene:FBgn0037802 transcript:FBtr0305358) HSP 1 Score: 66.2402 bits (160), Expect = 3.827e-11 Identity = 48/173 (27.75%), Postives = 78/173 (45.09%), Query Frame = 2
Query: 278 LSTPSGTDDQKFIVDICQKI--LTSKIKNIVIMAGAGISCPSGIPDFRSPGTGLYDNLKQYKIPYPEAIFDIDYFLQNPKPFFALAKELFPSGKYRPNKVHYFFRLLQEKKLLRRVYTQNIDGLERLAGLNDTNLVEAHGTFASASCVRCGEDY---SATQLKLKHSISEICE 781
L P D + + + CQ++ L K ++V+ GAGIS +GIPDFR P + ++ ++ + KP F ++ + + RP K H L E ++ V +QNIDGL +GL+ L E HG C +C + SA + + S+ C+
Sbjct: 18 LGAPESFDSDEVVAEKCQELAELIKKSGHVVLHTGAGISTSAGIPDFRGP----------------KGVWTLEE--KGEKPDFNVSFD-----EARPTKTHMAIIALIESGYVQYVISQNIDGLHLKSGLDRKYLSELHGNIYIEQCKKCRRQFVSPSAVETVGQKSLQRACK 167
BLAST of NAD-dependent protein deacetylase vs. Ensembl Fly
Match: Sirt4 (gene:FBgn0029783 transcript:FBtr0070852) HSP 1 Score: 65.855 bits (159), Expect = 5.511e-11 Identity = 48/149 (32.21%), Postives = 73/149 (48.99%), Query Frame = 2
Query: 287 PSGTDDQKFIVDICQKILTSKIKNIVIMAGAGISCPSGIPDFRSPGTGLYDNLKQYKIPYPEAIFDIDYFLQNP---KPFFALAKELFPS-GKYRPNKVHYFFRLLQEKKLLRRVYTQNIDGLERLAGLNDTNLVEAHGTFASASCVRC 721
P DD K + D L SK N++++ GAGIS SGIPD+RS G GLY + + E F+++ K ++A +P +PN H+ + ++ ++ V TQN+D L AG N+VE HG+ C+ C
Sbjct: 29 PVVEDDIKRLEDF----LLSK-PNVLVLTGAGISTESGIPDYRSEGVGLYARSNHKPVQHME-------FVKSSAVRKRYWARNFVGWPKFSATQPNATHHALARFEREERVQAVVTQNVDRLHTKAG--SRNVVEVHGSGYVVKCLSC 163
BLAST of NAD-dependent protein deacetylase vs. Ensembl Zebrafish
Match: sirt3 (sirtuin 3 [Source:ZFIN;Acc:ZDB-GENE-070112-1762]) HSP 1 Score: 203.371 bits (516), Expect = 2.146e-57 Identity = 95/149 (63.76%), Postives = 116/149 (77.85%), Query Frame = 2
Query: 305 QKFIVDICQKILTSKIKNIVIMAGAGISCPSGIPDFRSPGTGLYDNLKQYKIPYPEAIFDIDYFLQNPKPFFALAKELFPSGKYRPNKVHYFFRLLQEKKLLRRVYTQNIDGLERLAGLNDTNLVEAHGTFASASCVRCGEDYSATQLK 751
Q+ + DI +KI K K IV+MAGAGIS PSGIPDFRSPG+GLYDNL+QY +PY EAIF+I+YF NP PFFALAKEL+P G Y+PN HYF R+L +K+ L R+YTQNIDGLER+AG+ LVEAHGTFA+A+C C DY +L+
Sbjct: 85 QQTLEDIAEKIRERKFKRIVVMAGAGISTPSGIPDFRSPGSGLYDNLQQYNLPYAEAIFEINYFHHNPNPFFALAKELYP-GNYQPNLTHYFIRMLHDKEQLLRMYTQNIDGLERMAGIPPKMLVEAHGTFATATCTVCRRDYKGEELR 232 HSP 2 Score: 100.523 bits (249), Expect = 3.905e-22 Identity = 51/94 (54.26%), Postives = 62/94 (65.96%), Query Frame = 2
Query: 1106 CSKCRGIVKPDIVFFGEDLPSKFHLFRSDFQQADLLLVMGTSLEVEPFASIVDSTRFGTPRVLINRQPVGVFRSKRRVHDNCVLGKQTSVSELA 1387
C C+GI+KPDIVFFGE+LP F + +DF ADLL+VMGTSLEVEPFAS+ + R PR+LINR VG F S + H T V+EL
Sbjct: 243 CPTCKGIIKPDIVFFGEELPQHFFTYLTDFPIADLLIVMGTSLEVEPFASLAGAVRGSVPRLLINRDLVGPFASGSQRH--------TDVAELG 328
BLAST of NAD-dependent protein deacetylase vs. Ensembl Zebrafish
Match: sirt3 (sirtuin 3 [Source:ZFIN;Acc:ZDB-GENE-070112-1762]) HSP 1 Score: 203.371 bits (516), Expect = 2.184e-57 Identity = 95/149 (63.76%), Postives = 116/149 (77.85%), Query Frame = 2
Query: 305 QKFIVDICQKILTSKIKNIVIMAGAGISCPSGIPDFRSPGTGLYDNLKQYKIPYPEAIFDIDYFLQNPKPFFALAKELFPSGKYRPNKVHYFFRLLQEKKLLRRVYTQNIDGLERLAGLNDTNLVEAHGTFASASCVRCGEDYSATQLK 751
Q+ + DI +KI K K IV+MAGAGIS PSGIPDFRSPG+GLYDNL+QY +PY EAIF+I+YF NP PFFALAKEL+P G Y+PN HYF R+L +K+ L R+YTQNIDGLER+AG+ LVEAHGTFA+A+C C DY +L+
Sbjct: 85 QQTLEDIAEKIRERKFKRIVVMAGAGISTPSGIPDFRSPGSGLYDNLQQYNLPYAEAIFEINYFHHNPNPFFALAKELYP-GNYQPNLTHYFIRMLHDKEQLLRMYTQNIDGLERMAGIPPKMLVEAHGTFATATCTVCRRDYKGEELR 232 HSP 2 Score: 100.523 bits (249), Expect = 4.113e-22 Identity = 51/94 (54.26%), Postives = 62/94 (65.96%), Query Frame = 2
Query: 1106 CSKCRGIVKPDIVFFGEDLPSKFHLFRSDFQQADLLLVMGTSLEVEPFASIVDSTRFGTPRVLINRQPVGVFRSKRRVHDNCVLGKQTSVSELA 1387
C C+GI+KPDIVFFGE+LP F + +DF ADLL+VMGTSLEVEPFAS+ + R PR+LINR VG F S + H T V+EL
Sbjct: 243 CPTCKGIIKPDIVFFGEELPQHFFTYLTDFPIADLLIVMGTSLEVEPFASLAGAVRGSVPRLLINRDLVGPFASGSQRH--------TDVAELG 328
BLAST of NAD-dependent protein deacetylase vs. Ensembl Zebrafish
Match: si:dkey-103i16.6 (si:dkey-103i16.6 [Source:ZFIN;Acc:ZDB-GENE-061207-46]) HSP 1 Score: 196.052 bits (497), Expect = 1.067e-54 Identity = 92/159 (57.86%), Postives = 120/159 (75.47%), Query Frame = 2
Query: 278 LSTPSGTDDQKFIVDICQKILT-SKIKNIVIMAGAGISCPSGIPDFRSPGTGLYDNLKQYKIPYPEAIFDIDYFLQNPKPFFALAKELFPSGKYRPNKVHYFFRLLQEKKLLRRVYTQNIDGLERLAGLNDTNLVEAHGTFASASCVRCGEDYSATQLK 751
LS+PSG + ++ +++ +++NIV++AGAGIS SGIPDFR+PGTGLY NL +Y IPYPEA+F+IDYF NP PFF+LAKEL+P G +RPN VHYF R+L +K LL R+YTQNIDGLE+L G+ D LVEAHG+FA+A+C C Y A + K
Sbjct: 67 LSSPSGRSVSRGALETIGRLMKLGRVRNIVVVAGAGISTASGIPDFRTPGTGLYANLAKYDIPYPEAVFNIDYFSDNPHPFFSLAKELYP-GHHRPNYVHYFIRMLHQKGLLLRMYTQNIDGLEKLCGIPDDKLVEAHGSFATAACHLCYTPYPAEEAK 224 HSP 2 Score: 90.1225 bits (222), Expect = 1.301e-18 Identity = 60/171 (35.09%), Postives = 90/171 (52.63%), Query Frame = 2
Query: 929 HHRSFHPQLWVKNLNG--KMC*FP*IINCGSLSKNSLSNISGPKASLIIYL-----------ESIDKSEICYCSKCRGIVKPDIVFFGEDLPSKFHLFRSDFQQADLLLVMGTSLEV---EPFASIVDSTRFGTPRVLINRQPVGVF-RSKRRVHDNCVLGK-QTSVSELA 1387
H + +++ +N++G K+C P + L G A+ +L ++I + C+ C G VKP++VFFGEDLP K+ DF +ADLL++MGTSL+V EPFAS++++ + PR+L+NR VG F R R D LG SV +LA
Sbjct: 172 HQKGLLLRMYTQNIDGLEKLCGIP---------DDKLVEAHGSFATAACHLCYTPYPAEEAKQAIMNGSVPICTFCAGAVKPNVVFFGEDLPEKYFQHAEDFPKADLLIIMGTSLKVGLIEPFASLINTVKSTVPRLLLNRDAVGPFERRPLRRADYMELGDLSESVRKLA 333
BLAST of NAD-dependent protein deacetylase vs. Ensembl Zebrafish
Match: si:dkey-103i16.6 (si:dkey-103i16.6 [Source:ZFIN;Acc:ZDB-GENE-061207-46]) HSP 1 Score: 196.438 bits (498), Expect = 1.279e-54 Identity = 92/159 (57.86%), Postives = 120/159 (75.47%), Query Frame = 2
Query: 278 LSTPSGTDDQKFIVDICQKILT-SKIKNIVIMAGAGISCPSGIPDFRSPGTGLYDNLKQYKIPYPEAIFDIDYFLQNPKPFFALAKELFPSGKYRPNKVHYFFRLLQEKKLLRRVYTQNIDGLERLAGLNDTNLVEAHGTFASASCVRCGEDYSATQLK 751
LS+PSG + ++ +++ +++NIV++AGAGIS SGIPDFR+PGTGLY NL +Y IPYPEA+F+IDYF NP PFF+LAKEL+P G +RPN VHYF R+L +K LL R+YTQNIDGLE+L G+ D LVEAHG+FA+A+C C Y A + K
Sbjct: 89 LSSPSGRSVSRGALETIGRLMKLGRVRNIVVVAGAGISTASGIPDFRTPGTGLYANLAKYDIPYPEAVFNIDYFSDNPHPFFSLAKELYP-GHHRPNYVHYFIRMLHQKGLLLRMYTQNIDGLEKLCGIPDDKLVEAHGSFATAACHLCYTPYPAEEAK 246 HSP 2 Score: 94.7449 bits (234), Expect = 4.098e-20 Identity = 59/168 (35.12%), Postives = 91/168 (54.17%), Query Frame = 2
Query: 929 HHRSFHPQLWVKNLNG--KMC*FP*IINCGSLSKNSLSNISGPKASLIIYL-----------ESIDKSEICYCSKCRGIVKPDIVFFGEDLPSKFHLFRSDFQQADLLLVMGTSLEVEPFASIVDSTRFGTPRVLINRQPVGVF-RSKRRVHDNCVLGKQT-SVSELA 1387
H + +++ +N++G K+C P + L G A+ +L ++I + C+ C G VKP++VFFGEDLP K+ DF +ADLL++MGTSL++EPFAS++++ + PR+L+NR VG F R R D LG + SV +LA
Sbjct: 194 HQKGLLLRMYTQNIDGLEKLCGIP---------DDKLVEAHGSFATAACHLCYTPYPAEEAKQAIMNGSVPICTFCAGAVKPNVVFFGEDLPEKYFQHAEDFPKADLLMIMGTSLKIEPFASLINTVKSTVPRLLLNRDAVGPFERRPLRRADYMELGDLSESVRKLA 352
BLAST of NAD-dependent protein deacetylase vs. Ensembl Zebrafish
Match: sirt2 (sirtuin 2 (silent mating type information regulation 2, homolog) 2 (S. cerevisiae) [Source:NCBI gene;Acc:322309]) HSP 1 Score: 191.045 bits (484), Expect = 6.093e-53 Identity = 93/175 (53.14%), Postives = 125/175 (71.43%), Query Frame = 2
Query: 239 NEMIYLSSTFGRYLSTPSGTD--DQKFIVDICQKILTSKIKNIVIMAGAGISCPSGIPDFRSPGTGLYDNLKQYKIPYPEAIFDIDYFLQNPKPFFALAKELFPSGKYRPNKVHYFFRLLQEKKLLRRVYTQNIDGLERLAGLNDTNLVEAHGTFASASCVR--CGEDYSATQLK 751
EM +L S F R L G D+ + + + IL+ K KNI+ M GAGIS +GIPDFRSPGTGLY NL++Y +PYPEAIF IDYF ++P+PFFALA+EL+P G+++P HYF ++L++K LLRR Y+QNID LER+AGL +L+EAHGTF ++ CV C ++YS +K
Sbjct: 35 TEMDFLRSLFSRTLGLSPGDKVLDELTLDSVARYILSGKCKNIICMVGAGISTSAGIPDFRSPGTGLYANLQKYNLPYPEAIFQIDYFKKHPEPFFALARELYP-GQFKPTVCHYFIKMLKDKGLLRRCYSQNIDTLERVAGLEGEDLIEAHGTFHTSHCVSFLCRKEYSMDWMK 208 HSP 2 Score: 85.1149 bits (209), Expect = 5.892e-17 Identity = 41/75 (54.67%), Postives = 52/75 (69.33%), Query Frame = 2
Query: 1094 EICYCSKCRGIVKPDIVFFGEDLPSKFHL-FRSDFQQADLLLVMGTSLEVEPFASIVDSTRFGTPRVLINRQPVG 1315
EI C C +VKPDIVFFGE LPS+F ++DF Q DLL++MGTSL+V+PFAS+V PR+LIN + G
Sbjct: 215 EIPKCDSCGSLVKPDIVFFGESLPSRFFTSMKADFPQCDLLIIMGTSLQVQPFASLVSRVSNRCPRLLINMEKTG 289
BLAST of NAD-dependent protein deacetylase vs. Ensembl Xenopus
Match: SIRT2 (sirtuin 2 [Source:NCBI gene;Acc:100489469]) HSP 1 Score: 196.052 bits (497), Expect = 6.536e-56 Identity = 100/177 (56.50%), Postives = 126/177 (71.19%), Query Frame = 2
Query: 239 NEMIYLSSTFGRYLS--TPSGTDDQKFIVDICQKILTSKIKNIVIMAGAGISCPSGIPDFRSPGTGLYDNLKQYKIPYPEAIFDIDYFLQNPKPFFALAKELFPSGKYRPNKVHYFFRLLQEKKLLRRVYTQNIDGLERLAGLNDTNLVEAHGTFASASCVR--CGEDYSATQLKLK 757
+EM YL + F R L TP D+ I I + +L+ K KN+V M GAGIS +GIPDFRSPG+GLY NL++Y +PYPEAIF I YF +NP+PFFALA+ELFP G+++P HYF RLL+EK LL R Y+QNID LER+AGL +LVEAHGTF S+ CV C +YS + +K K
Sbjct: 12 SEMDYLRNLFSRTLGIGTPEKVLDELSIEGISRFMLSEKCKNVVCMVGAGISTSAGIPDFRSPGSGLYSNLQKYNLPYPEAIFQIGYFKENPEPFFALARELFP-GQFKPTICHYFIRLLKEKGLLLRCYSQNIDTLERVAGLTSDDLVEAHGTFHSSHCVDTFCRAEYSLSWMKEK 187 HSP 2 Score: 54.6842 bits (130), Expect = 2.652e-7 Identity = 27/53 (50.94%), Postives = 38/53 (71.70%), Query Frame = 2
Query: 1157 DLPSKFHLFRSDFQQADLLLVMGTSLEVEPFASIVDSTRFGTPRVLINRQPVG 1315
+L S+F +DF + DLL+VMGTSL+V+PFAS+V TPR+LIN++ G
Sbjct: 201 NLKSRF----TDFPKVDLLIVMGTSLQVQPFASLVSKVSSKTPRLLINKELAG 249
BLAST of NAD-dependent protein deacetylase vs. Ensembl Xenopus
Match: SIRT2 (sirtuin 2 [Source:NCBI gene;Acc:100489469]) HSP 1 Score: 194.512 bits (493), Expect = 7.773e-55 Identity = 100/177 (56.50%), Postives = 126/177 (71.19%), Query Frame = 2
Query: 239 NEMIYLSSTFGRYLS--TPSGTDDQKFIVDICQKILTSKIKNIVIMAGAGISCPSGIPDFRSPGTGLYDNLKQYKIPYPEAIFDIDYFLQNPKPFFALAKELFPSGKYRPNKVHYFFRLLQEKKLLRRVYTQNIDGLERLAGLNDTNLVEAHGTFASASCVR--CGEDYSATQLKLK 757
+EM YL + F R L TP D+ I I + +L+ K KN+V M GAGIS +GIPDFRSPG+GLY NL++Y +PYPEAIF I YF +NP+PFFALA+ELFP G+++P HYF RLL+EK LL R Y+QNID LER+AGL +LVEAHGTF S+ CV C +YS + +K K
Sbjct: 12 SEMDYLRNLFSRTLGIGTPEKVLDELSIEGISRFMLSEKCKNVVCMVGAGISTSAGIPDFRSPGSGLYSNLQKYNLPYPEAIFQIGYFKENPEPFFALARELFP-GQFKPTICHYFIRLLKEKGLLLRCYSQNIDTLERVAGLTSDDLVEAHGTFHSSHCVDTFCRAEYSLSWMKEK 187 HSP 2 Score: 74.7146 bits (182), Expect = 9.215e-14 Identity = 40/70 (57.14%), Postives = 48/70 (68.57%), Query Frame = 2
Query: 1058 SLIIYLESIDKSEICYCSKCRGIVKPDIVFFGEDLPSK-FHLFRSDFQQADLLLVMGTSLEVEPFASIVD 1264
SL E I I C KC +VKPDIVFFGE LPS+ F +SDF + DLL+VMGTSL+V+PFAS+ D
Sbjct: 180 SLSWMKEKIFSDLIPKCEKCNNLVKPDIVFFGESLPSRFFSAIKSDFPKVDLLIVMGTSLQVQPFASLGD 249
BLAST of NAD-dependent protein deacetylase vs. Ensembl Xenopus
Match: SIRT2 (sirtuin 2 [Source:NCBI gene;Acc:100489469]) HSP 1 Score: 196.052 bits (497), Expect = 4.137e-54 Identity = 100/177 (56.50%), Postives = 126/177 (71.19%), Query Frame = 2
Query: 239 NEMIYLSSTFGRYLS--TPSGTDDQKFIVDICQKILTSKIKNIVIMAGAGISCPSGIPDFRSPGTGLYDNLKQYKIPYPEAIFDIDYFLQNPKPFFALAKELFPSGKYRPNKVHYFFRLLQEKKLLRRVYTQNIDGLERLAGLNDTNLVEAHGTFASASCVR--CGEDYSATQLKLK 757
+EM YL + F R L TP D+ I I + +L+ K KN+V M GAGIS +GIPDFRSPG+GLY NL++Y +PYPEAIF I YF +NP+PFFALA+ELFP G+++P HYF RLL+EK LL R Y+QNID LER+AGL +LVEAHGTF S+ CV C +YS + +K K
Sbjct: 66 SEMDYLRNLFSRTLGIGTPEKVLDELSIEGISRFMLSEKCKNVVCMVGAGISTSAGIPDFRSPGSGLYSNLQKYNLPYPEAIFQIGYFKENPEPFFALARELFP-GQFKPTICHYFIRLLKEKGLLLRCYSQNIDTLERVAGLTSDDLVEAHGTFHSSHCVDTFCRAEYSLSWMKEK 241 HSP 2 Score: 90.1225 bits (222), Expect = 2.387e-18 Identity = 47/87 (54.02%), Postives = 58/87 (66.67%), Query Frame = 2
Query: 1058 SLIIYLESIDKSEICYCSKCRGIVKPDIVFFGEDLPSKF-HLFRSDFQQADLLLVMGTSLEVEPFASIVDSTRFGTPRVLINRQPVG 1315
SL E I I C KC +VKPDIVFFGE LPS+F +SDF + DLL+VMGTSL+V+PFAS+V TPR+LIN++ G
Sbjct: 234 SLSWMKEKIFSDLIPKCEKCNNLVKPDIVFFGESLPSRFFSAIKSDFPKVDLLIVMGTSLQVQPFASLVSKVSSKTPRLLINKELAG 320
BLAST of NAD-dependent protein deacetylase vs. Ensembl Xenopus
Match: SIRT2 (sirtuin 2 [Source:NCBI gene;Acc:100489469]) HSP 1 Score: 191.815 bits (486), Expect = 3.780e-53 Identity = 98/173 (56.65%), Postives = 123/173 (71.10%), Query Frame = 2
Query: 251 YLSSTFGRYLS--TPSGTDDQKFIVDICQKILTSKIKNIVIMAGAGISCPSGIPDFRSPGTGLYDNLKQYKIPYPEAIFDIDYFLQNPKPFFALAKELFPSGKYRPNKVHYFFRLLQEKKLLRRVYTQNIDGLERLAGLNDTNLVEAHGTFASASCVR--CGEDYSATQLKLK 757
YL + F R L TP D+ I I + +L+ K KN+V M GAGIS +GIPDFRSPG+GLY NL++Y +PYPEAIF I YF +NP+PFFALA+ELFP G+++P HYF RLL+EK LL R Y+QNID LER+AGL +LVEAHGTF S+ CV C +YS + +K K
Sbjct: 67 YLRNLFSRTLGIGTPEKVLDELSIEGISRFMLSEKCKNVVCMVGAGISTSAGIPDFRSPGSGLYSNLQKYNLPYPEAIFQIGYFKENPEPFFALARELFP-GQFKPTICHYFIRLLKEKGLLLRCYSQNIDTLERVAGLTSDDLVEAHGTFHSSHCVDTFCRAEYSLSWMKEK 238 HSP 2 Score: 75.485 bits (184), Expect = 1.163e-13 Identity = 40/70 (57.14%), Postives = 48/70 (68.57%), Query Frame = 2
Query: 1058 SLIIYLESIDKSEICYCSKCRGIVKPDIVFFGEDLPSK-FHLFRSDFQQADLLLVMGTSLEVEPFASIVD 1264
SL E I I C KC +VKPDIVFFGE LPS+ F +SDF + DLL+VMGTSL+V+PFAS+ D
Sbjct: 231 SLSWMKEKIFSDLIPKCEKCNNLVKPDIVFFGESLPSRFFSAIKSDFPKVDLLIVMGTSLQVQPFASLGD 300
BLAST of NAD-dependent protein deacetylase vs. Ensembl Xenopus
Match: hoga1 (4-hydroxy-2-oxoglutarate aldolase 1 [Source:Xenbase;Acc:XB-GENE-957775]) HSP 1 Score: 190.66 bits (483), Expect = 2.737e-52 Identity = 93/144 (64.58%), Postives = 109/144 (75.69%), Query Frame = 2
Query: 320 DICQKILTSKIKNIVIMAGAGISCPSGIPDFRSPGTGLYDNLKQYKIPYPEAIFDIDYFLQNPKPFFALAKELFPSGKYRPNKVHYFFRLLQEKKLLRRVYTQNIDGLERLAGLNDTNLVEAHGTFASASCVRCGEDYSATQLK 751
DI I + NI++MAGAGIS SGIPDFR+PG+GLYDNL++Y IPYPEAIFDI+YF+ NP PFF LAKELFP GKY+PN VHYF +LL +K LL R YTQNIDGLERLAG+ +VE HGTF SASC C + A + K
Sbjct: 116 DILDLITKNCCTNIIVMAGAGISTASGIPDFRTPGSGLYDNLQKYDIPYPEAIFDINYFVCNPNPFFHLAKELFP-GKYKPNLVHYFIKLLHDKGLLLRCYTQNIDGLERLAGIPVEKIVEVHGTFFSASCSLCYTPFPANEAK 258 HSP 2 Score: 97.0561 bits (240), Expect = 1.284e-20 Identity = 53/100 (53.00%), Postives = 65/100 (65.00%), Query Frame = 2
Query: 1106 CSKCRGIVKPDIVFFGEDLPSKFHLFRSDFQQADLLLVMGTSLEVEPFASIVDSTRFGTPRVLINRQPVGVFRSKR-RVHDNCVLGK-----QTSVSELA 1387
C C G VKPDIVFFGEDLP F DF +ADLL++MGTSL++EPFAS+V++ + PR+LINR+ VG F KR R D LG T VS L+
Sbjct: 269 CKFCAGPVKPDIVFFGEDLPQTFTQAYQDFPKADLLIIMGTSLKIEPFASLVNTVKPSIPRLLINREKVGPFAKKRLRRRDVAELGDLCDIIHTMVSRLS 368
BLAST of NAD-dependent protein deacetylase vs. Ensembl Mouse
Match: Sirt3 (sirtuin 3 [Source:MGI Symbol;Acc:MGI:1927665]) HSP 1 Score: 190.66 bits (483), Expect = 3.294e-54 Identity = 92/165 (55.76%), Postives = 117/165 (70.91%), Query Frame = 2
Query: 302 DQKF-IVDICQKILTSKIKNIVIMAGAGISCPSGIPDFRSPGTGLYDNLKQYKIPYPEAIFDIDYFLQNPKPFFALAKELFPSGKYRPNKVHYFFRLLQEKKLLRRVYTQNIDGLERLAGLNDTNLVEAHGTFASASCVRC-----GEDYSATQLKLKHSISEIC 778
++KF + D+ + + T +V+M GAGIS PSGIPDFRSPG+GLY NL+QY IPYPEAIF++ +F NPKPFF LAKEL+P G YRPN HYF RLL +K+LL R+YTQNIDGLER +G+ + LVEAHGTF +A+C C GED A + + +C
Sbjct: 55 EKKFSLQDVAELLRTRACSRVVVMVGAGISTPSGIPDFRSPGSGLYSNLQQYDIPYPEAIFELGFFFHNPKPFFMLAKELYP-GHYRPNVTHYFLRLLHDKELLLRLYTQNIDGLERASGIPASKLVEAHGTFVTATCTVCRRSFPGEDIWADVMADRVPRCPVC 218 HSP 2 Score: 65.855 bits (159), Expect = 3.407e-11 Identity = 29/44 (65.91%), Postives = 35/44 (79.55%), Query Frame = 2
Query: 1106 CSKCRGIVKPDIVFFGEDLPSKFHLFRSDFQQADLLLVMGTSLE 1237
C C G+VKPDIVFFGE LP++F L +DF ADLLL++GTSLE
Sbjct: 215 CPVCTGVVKPDIVFFGEQLPARFLLHMADFALADLLLILGTSLE 258
BLAST of NAD-dependent protein deacetylase vs. Ensembl Mouse
Match: Sirt3 (sirtuin 3 [Source:MGI Symbol;Acc:MGI:1927665]) HSP 1 Score: 181.415 bits (459), Expect = 5.553e-52 Identity = 85/140 (60.71%), Postives = 105/140 (75.00%), Query Frame = 2
Query: 368 MAGAGISCPSGIPDFRSPGTGLYDNLKQYKIPYPEAIFDIDYFLQNPKPFFALAKELFPSGKYRPNKVHYFFRLLQEKKLLRRVYTQNIDGLERLAGLNDTNLVEAHGTFASASCVRCGEDYSATQLKLK--HSISEICE 781
M GAGIS PSGIPDFRSPG+GLY NL+QY IPYPEAIF++ +F NPKPFF LAKEL+P G YRPN HYF RLL +K+LL R+YTQNIDGLER +G+ + LVEAHGTF +A+C C + + ++ S+SE +
Sbjct: 1 MVGAGISTPSGIPDFRSPGSGLYSNLQQYDIPYPEAIFELGFFFHNPKPFFMLAKELYP-GHYRPNVTHYFLRLLHDKELLLRLYTQNIDGLERASGIPASKLVEAHGTFVTATCTVCRRSFPGEDIWVEPFASLSEAVQ 139
BLAST of NAD-dependent protein deacetylase vs. Ensembl Mouse
Match: Sirt3 (sirtuin 3 [Source:MGI Symbol;Acc:MGI:1927665]) HSP 1 Score: 181.03 bits (458), Expect = 9.744e-52 Identity = 87/142 (61.27%), Postives = 104/142 (73.24%), Query Frame = 2
Query: 368 MAGAGISCPSGIPDFRSPGTGLYDNLKQYKIPYPEAIFDIDYFLQNPKPFFALAKELFPSGKYRPNKVHYFFRLLQEKKLLRRVYTQNIDGLERLAGLNDTNLVEAHGTFASASCVRC-----GEDYSATQLKLKHSISEIC 778
M GAGIS PSGIPDFRSPG+GLY NL+QY IPYPEAIF++ +F NPKPFF LAKEL+P G YRPN HYF RLL +K+LL R+YTQNIDGLER +G+ + LVEAHGTF +A+C C GED A + + +C
Sbjct: 1 MVGAGISTPSGIPDFRSPGSGLYSNLQQYDIPYPEAIFELGFFFHNPKPFFMLAKELYP-GHYRPNVTHYFLRLLHDKELLLRLYTQNIDGLERASGIPASKLVEAHGTFVTATCTVCRRSFPGEDIWADVMADRVPRCPVC 141 HSP 2 Score: 65.855 bits (159), Expect = 1.064e-11 Identity = 29/45 (64.44%), Postives = 36/45 (80.00%), Query Frame = 2
Query: 1106 CSKCRGIVKPDIVFFGEDLPSKFHLFRSDFQQADLLLVMGTSLEV 1240
C C G+VKPDIVFFGE LP++F L +DF ADLLL++GTSLE+
Sbjct: 138 CPVCTGVVKPDIVFFGEQLPARFLLHMADFALADLLLILGTSLEM 182
BLAST of NAD-dependent protein deacetylase vs. Ensembl Mouse
Match: Sirt3 (sirtuin 3 [Source:MGI Symbol;Acc:MGI:1927665]) HSP 1 Score: 182.185 bits (461), Expect = 3.679e-51 Identity = 87/142 (61.27%), Postives = 104/142 (73.24%), Query Frame = 2
Query: 368 MAGAGISCPSGIPDFRSPGTGLYDNLKQYKIPYPEAIFDIDYFLQNPKPFFALAKELFPSGKYRPNKVHYFFRLLQEKKLLRRVYTQNIDGLERLAGLNDTNLVEAHGTFASASCVRC-----GEDYSATQLKLKHSISEIC 778
M GAGIS PSGIPDFRSPG+GLY NL+QY IPYPEAIF++ +F NPKPFF LAKEL+P G YRPN HYF RLL +K+LL R+YTQNIDGLER +G+ + LVEAHGTF +A+C C GED A + + +C
Sbjct: 1 MVGAGISTPSGIPDFRSPGSGLYSNLQQYDIPYPEAIFELGFFFHNPKPFFMLAKELYP-GHYRPNVTHYFLRLLHDKELLLRLYTQNIDGLERASGIPASKLVEAHGTFVTATCTVCRRSFPGEDIWADVMADRVPRCPVC 141 HSP 2 Score: 98.2117 bits (243), Expect = 3.618e-22 Identity = 53/110 (48.18%), Postives = 66/110 (60.00%), Query Frame = 2
Query: 1106 CSKCRGIVKPDIVFFGEDLPSKFHLFRSDFQQADLLLVMGTSLEVEPFASIVDSTRFGTPRVLINRQPVGVFRSKRRVHDNCVLGKQTSVSELAGTDCGRRSSALTLLQQ 1435
C C G+VKPDIVFFGE LP++F L +DF ADLLL++GTSLEVEPFAS+ ++ + PR+LINR VG F R D LG E G L L+Q+
Sbjct: 138 CPVCTGVVKPDIVFFGEQLPARFLLHMADFALADLLLILGTSLEVEPFASLSEAVQKSVPRLLINRDLVGPFVLSPRRKDVVQLGDVVHGVERLVDLLGWTQELLDLMQR 247
BLAST of NAD-dependent protein deacetylase vs. Ensembl Mouse
Match: Sirt3 (sirtuin 3 [Source:MGI Symbol;Acc:MGI:1927665]) HSP 1 Score: 182.185 bits (461), Expect = 3.679e-51 Identity = 87/142 (61.27%), Postives = 104/142 (73.24%), Query Frame = 2
Query: 368 MAGAGISCPSGIPDFRSPGTGLYDNLKQYKIPYPEAIFDIDYFLQNPKPFFALAKELFPSGKYRPNKVHYFFRLLQEKKLLRRVYTQNIDGLERLAGLNDTNLVEAHGTFASASCVRC-----GEDYSATQLKLKHSISEIC 778
M GAGIS PSGIPDFRSPG+GLY NL+QY IPYPEAIF++ +F NPKPFF LAKEL+P G YRPN HYF RLL +K+LL R+YTQNIDGLER +G+ + LVEAHGTF +A+C C GED A + + +C
Sbjct: 1 MVGAGISTPSGIPDFRSPGSGLYSNLQQYDIPYPEAIFELGFFFHNPKPFFMLAKELYP-GHYRPNVTHYFLRLLHDKELLLRLYTQNIDGLERASGIPASKLVEAHGTFVTATCTVCRRSFPGEDIWADVMADRVPRCPVC 141 HSP 2 Score: 98.2117 bits (243), Expect = 3.618e-22 Identity = 53/110 (48.18%), Postives = 66/110 (60.00%), Query Frame = 2
Query: 1106 CSKCRGIVKPDIVFFGEDLPSKFHLFRSDFQQADLLLVMGTSLEVEPFASIVDSTRFGTPRVLINRQPVGVFRSKRRVHDNCVLGKQTSVSELAGTDCGRRSSALTLLQQ 1435
C C G+VKPDIVFFGE LP++F L +DF ADLLL++GTSLEVEPFAS+ ++ + PR+LINR VG F R D LG E G L L+Q+
Sbjct: 138 CPVCTGVVKPDIVFFGEQLPARFLLHMADFALADLLLILGTSLEVEPFASLSEAVQKSVPRLLINRDLVGPFVLSPRRKDVVQLGDVVHGVERLVDLLGWTQELLDLMQR 247
BLAST of NAD-dependent protein deacetylase vs. UniProt/SwissProt
Match: sp|Q8R104|SIR3_MOUSE (NAD-dependent protein deacetylase sirtuin-3 OS=Mus musculus OX=10090 GN=Sirt3 PE=1 SV=2) HSP 1 Score: 191.045 bits (484), Expect = 1.469e-52 Identity = 92/165 (55.76%), Postives = 117/165 (70.91%), Query Frame = 2
Query: 302 DQKF-IVDICQKILTSKIKNIVIMAGAGISCPSGIPDFRSPGTGLYDNLKQYKIPYPEAIFDIDYFLQNPKPFFALAKELFPSGKYRPNKVHYFFRLLQEKKLLRRVYTQNIDGLERLAGLNDTNLVEAHGTFASASCVRC-----GEDYSATQLKLKHSISEIC 778
++KF + D+ + + T +V+M GAGIS PSGIPDFRSPG+GLY NL+QY IPYPEAIF++ +F NPKPFF LAKEL+P G YRPN HYF RLL +K+LL R+YTQNIDGLER +G+ + LVEAHGTF +A+C C GED A + + +C
Sbjct: 55 EKKFSLQDVAELLRTRACSRVVVMVGAGISTPSGIPDFRSPGSGLYSNLQQYDIPYPEAIFELGFFFHNPKPFFMLAKELYP-GHYRPNVTHYFLRLLHDKELLLRLYTQNIDGLERASGIPASKLVEAHGTFVTATCTVCRRSFPGEDIWADVMADRVPRCPVC 218 HSP 2 Score: 97.8265 bits (242), Expect = 1.692e-20 Identity = 53/110 (48.18%), Postives = 66/110 (60.00%), Query Frame = 2
Query: 1106 CSKCRGIVKPDIVFFGEDLPSKFHLFRSDFQQADLLLVMGTSLEVEPFASIVDSTRFGTPRVLINRQPVGVFRSKRRVHDNCVLGKQTSVSELAGTDCGRRSSALTLLQQ 1435
C C G+VKPDIVFFGE LP++F L +DF ADLLL++GTSLEVEPFAS+ ++ + PR+LINR VG F R D LG E G L L+Q+
Sbjct: 215 CPVCTGVVKPDIVFFGEQLPARFLLHMADFALADLLLILGTSLEVEPFASLSEAVQKSVPRLLINRDLVGPFVLSPRRKDVVQLGDVVHGVERLVDLLGWTQELLDLMQR 324
BLAST of NAD-dependent protein deacetylase vs. UniProt/SwissProt
Match: sp|Q7ZVK3|SIR2_DANRE (NAD-dependent protein deacetylase sirtuin-2 OS=Danio rerio OX=7955 GN=sirt2 PE=1 SV=1) HSP 1 Score: 191.045 bits (484), Expect = 5.264e-52 Identity = 93/175 (53.14%), Postives = 125/175 (71.43%), Query Frame = 2
Query: 239 NEMIYLSSTFGRYLSTPSGTD--DQKFIVDICQKILTSKIKNIVIMAGAGISCPSGIPDFRSPGTGLYDNLKQYKIPYPEAIFDIDYFLQNPKPFFALAKELFPSGKYRPNKVHYFFRLLQEKKLLRRVYTQNIDGLERLAGLNDTNLVEAHGTFASASCVR--CGEDYSATQLK 751
EM +L S F R L G D+ + + + IL+ K KNI+ M GAGIS +GIPDFRSPGTGLY NL++Y +PYPEAIF IDYF ++P+PFFALA+EL+P G+++P HYF ++L++K LLRR Y+QNID LER+AGL +L+EAHGTF ++ CV C ++YS +K
Sbjct: 35 TEMDFLRSLFSRTLGLSPGDKVLDELTLDSVARYILSGKCKNIICMVGAGISTSAGIPDFRSPGTGLYANLQKYNLPYPEAIFQIDYFKKHPEPFFALARELYP-GQFKPTVYHYFIKMLKDKGLLRRCYSQNIDTLERVAGLEGEDLIEAHGTFHTSHCVSFLCRKEYSMDWMK 208 HSP 2 Score: 85.1149 bits (209), Expect = 4.174e-16 Identity = 41/75 (54.67%), Postives = 52/75 (69.33%), Query Frame = 2
Query: 1094 EICYCSKCRGIVKPDIVFFGEDLPSKFHL-FRSDFQQADLLLVMGTSLEVEPFASIVDSTRFGTPRVLINRQPVG 1315
EI C C +VKPDIVFFGE LPS+F ++DF Q DLL++MGTSL+V+PFAS+V PR+LIN + G
Sbjct: 215 EIPKCDSCGSLVKPDIVFFGESLPSRFFTSMKADFPQCDLLIIMGTSLQVQPFASLVSRVSNRCPRLLINMEKTG 289
BLAST of NAD-dependent protein deacetylase vs. UniProt/SwissProt
Match: sp|Q9NTG7|SIR3_HUMAN (NAD-dependent protein deacetylase sirtuin-3, mitochondrial OS=Homo sapiens OX=9606 GN=SIRT3 PE=1 SV=2) HSP 1 Score: 191.045 bits (484), Expect = 9.218e-52 Identity = 90/158 (56.96%), Postives = 113/158 (71.52%), Query Frame = 2
Query: 320 DICQKILTSKIKNIVIMAGAGISCPSGIPDFRSPGTGLYDNLKQYKIPYPEAIFDIDYFLQNPKPFFALAKELFPSGKYRPNKVHYFFRLLQEKKLLRRVYTQNIDGLERLAGLNDTNLVEAHGTFASASCVRC-----GEDYSATQLKLKHSISEIC 778
D+ + I + +V+M GAGIS PSGIPDFRSPG+GLY NL+QY +PYPEAIF++ +F NPKPFF LAKEL+P G Y+PN HYF RLL +K LL R+YTQNIDGLER++G+ + LVEAHGTFASA+C C GED A + + +C
Sbjct: 127 DVAELIRARACQRVVVMVGAGISTPSGIPDFRSPGSGLYSNLQQYDLPYPEAIFELPFFFHNPKPFFTLAKELYP-GNYKPNVTHYFLRLLHDKGLLLRLYTQNIDGLERVSGIPASKLVEAHGTFASATCTVCQRPFPGEDIRADVMADRVPRCPVC 283 HSP 2 Score: 96.2857 bits (238), Expect = 1.151e-19 Identity = 48/85 (56.47%), Postives = 56/85 (65.88%), Query Frame = 2
Query: 1106 CSKCRGIVKPDIVFFGEDLPSKFHLFRSDFQQADLLLVMGTSLEVEPFASIVDSTRFGTPRVLINRQPVGVFRSKRRVHDNCVLG 1360
C C G+VKPDIVFFGE LP +F L DF ADLLL++GTSLEVEPFAS+ ++ R PR+LINR VG R D LG
Sbjct: 280 CPVCTGVVKPDIVFFGEPLPQRFLLHVVDFPMADLLLILGTSLEVEPFASLTEAVRSSVPRLLINRDLVGPLAWHPRSRDVAQLG 364
BLAST of NAD-dependent protein deacetylase vs. UniProt/SwissProt
Match: sp|Q5RBF1|SIR2_PONAB (NAD-dependent protein deacetylase sirtuin-2 OS=Pongo abelii OX=9601 GN=SIRT2 PE=2 SV=1) HSP 1 Score: 177.178 bits (448), Expect = 1.832e-47 Identity = 89/186 (47.85%), Postives = 127/186 (68.28%), Query Frame = 2
Query: 245 MIYLSSTFGRYLSTPSGTD---DQKFIVDICQKILTSKIKNIVIMAGAGISCPSGIPDFRSPGTGLYDNLKQYKIPYPEAIFDIDYFLQNPKPFFALAKELFPSGKYRPNKVHYFFRLLQEKKLLRRVYTQNIDGLERLAGLNDTNLVEAHGTFASASCV--RCGEDYSATQLKLK--HSISEICE 781
M +L + F + LS S + D+ + + + + + + + ++ + GAGIS +GIPDFRSP TGLYDNL++Y +PYPEAIF+I YF ++P+PFFALAKEL+P G+++P HYF RLL++K LL R YTQNID LER+AGL +LVEAHGTF ++ CV C +Y + +K K ++ CE
Sbjct: 1 MDFLRNLFSQTLSLGSQKERLLDELTLEGVARYMQSERCRRVICLVGAGISTSAGIPDFRSPSTGLYDNLEKYHLPYPEAIFEISYFKKHPEPFFALAKELYP-GQFKPTICHYFMRLLKDKGLLLRCYTQNIDTLERIAGLEQEDLVEAHGTFYTSHCVSASCRHEYPLSWMKEKIFSEVTPKCE 185 HSP 2 Score: 88.9669 bits (219), Expect = 1.996e-17 Identity = 40/71 (56.34%), Postives = 53/71 (74.65%), Query Frame = 2
Query: 1106 CSKCRGIVKPDIVFFGEDLPSKF-HLFRSDFQQADLLLVMGTSLEVEPFASIVDSTRFGTPRVLINRQPVG 1315
C C+ +VKPDIVFFGE LP++F +SDF + DLLLVMGTSL+V+PFAS++ TPR+LIN++ G
Sbjct: 184 CEDCQSLVKPDIVFFGESLPARFFSCMQSDFLKVDLLLVMGTSLQVQPFASLISKAPLSTPRLLINKEKAG 254
BLAST of NAD-dependent protein deacetylase vs. UniProt/SwissProt
Match: sp|Q5RJQ4|SIR2_RAT (NAD-dependent protein deacetylase sirtuin-2 OS=Rattus norvegicus OX=10116 GN=Sirt2 PE=1 SV=1) HSP 1 Score: 176.407 bits (446), Expect = 2.654e-47 Identity = 87/176 (49.43%), Postives = 124/176 (70.45%), Query Frame = 2
Query: 245 MIYLSSTFGRYLSTPSGTD---DQKFIVDICQKILTSKIKNIVIMAGAGISCPSGIPDFRSPGTGLYDNLKQYKIPYPEAIFDIDYFLQNPKPFFALAKELFPSGKYRPNKVHYFFRLLQEKKLLRRVYTQNIDGLERLAGLNDTNLVEAHGTFASASCVR--CGEDYSATQLKLK 757
M +L + F + L S + D+ + + + + + + + ++ + GAGIS +GIPDFRSP TGLY NL++Y +PYPEAIF+I YF ++P+PFFALAKEL+P G+++P HYF RLL+EK LL R YTQNID LER+AGL +LVEAHGTF ++ CV CG++Y+ + +K K
Sbjct: 1 MDFLRNLFTQTLGLGSQKERLLDELTLEGVTRYMQSERCRRVICLVGAGISTSAGIPDFRSPSTGLYANLEKYHLPYPEAIFEISYFKKHPEPFFALAKELYP-GQFKPTICHYFIRLLKEKGLLLRCYTQNIDTLERVAGLEPQDLVEAHGTFYTSHCVNTSCGKEYTMSWMKEK 175 HSP 2 Score: 90.8929 bits (224), Expect = 4.333e-18 Identity = 39/71 (54.93%), Postives = 54/71 (76.06%), Query Frame = 2
Query: 1106 CSKCRGIVKPDIVFFGEDLPSKF-HLFRSDFQQADLLLVMGTSLEVEPFASIVDSTRFGTPRVLINRQPVG 1315
C KC+ +VKPDIVFFGE+LP +F +SDF + DLL++MGTSL+V+PFAS++ TPR+LIN++ G
Sbjct: 184 CEKCQNVVKPDIVFFGENLPPRFFSCMQSDFSKVDLLIIMGTSLQVQPFASLISKAPLATPRLLINKEKTG 254
BLAST of NAD-dependent protein deacetylase vs. TrEMBL
Match: C3Z1Z2 (Deacetylase sirtuin-type domain-containing protein (Fragment) OS=Branchiostoma floridae OX=7739 GN=BRAFLDRAFT_223028 PE=4 SV=1) HSP 1 Score: 218.009 bits (554), Expect = 1.955e-60 Identity = 102/146 (69.86%), Postives = 121/146 (82.88%), Query Frame = 2
Query: 314 IVDICQKILTSKIKNIVIMAGAGISCPSGIPDFRSPGTGLYDNLKQYKIPYPEAIFDIDYFLQNPKPFFALAKELFPSGKYRPNKVHYFFRLLQEKKLLRRVYTQNIDGLERLAGLNDTNLVEAHGTFASASCVRCGEDYSATQLK 751
I D+ + IL +K KN+V+MAGAGIS PSGIPDFRSPGTGLYDNL+QY IPYPEAIFDIDYF + +PF+ LAKEL+P G YRPN VHYF RLL EK LL R+YTQNIDGLER++G+ ++ LVEAHGTFA+ASC+RC YS Q+K
Sbjct: 1 IDDVARYILANKCKNVVVMAGAGISTPSGIPDFRSPGTGLYDNLQQYNIPYPEAIFDIDYFHMDSRPFYTLAKELYP-GNYRPNYVHYFIRLLHEKGLLLRMYTQNIDGLERMSGIPESKLVEAHGTFATASCIRCNAKYSGKQIK 145 HSP 2 Score: 103.219 bits (256), Expect = 1.889e-20 Identity = 57/98 (58.16%), Postives = 67/98 (68.37%), Query Frame = 2
Query: 1079 SIDKSEICYCSK---CRGIVKPDIVFFGEDLPSKFHLFRSDFQQADLLLVMGTSLEVEPFASIVDSTRFGTPRVLINRQPVGVF-RSKRRVHDNCVLG 1360
+I K +I C+ C+G +KPDIVFFGEDLP +F+ + DF DLLLVMGTSLEVEPFASIV+S+R PRVL NR PVG F R R D LG
Sbjct: 147 AIMKGDIPKCTNSKWCKGKIKPDIVFFGEDLPRRFYYYLKDFPLCDLLLVMGTSLEVEPFASIVNSSRGYVPRVLFNRDPVGPFGRVPLRDTDCAELG 244
BLAST of NAD-dependent protein deacetylase vs. TrEMBL
Match: H2ZB27 (NAD-dependent protein deacetylase OS=Ciona savignyi OX=51511 PE=3 SV=1) HSP 1 Score: 218.009 bits (554), Expect = 3.299e-60 Identity = 100/148 (67.57%), Postives = 119/148 (80.41%), Query Frame = 2
Query: 314 IVDICQKILTSKIKNIVIMAGAGISCPSGIPDFRSPGTGLYDNLKQYKIPYPEAIFDIDYFLQNPKPFFALAKELFPSGKYRPNKVHYFFRLLQEKKLLRRVYTQNIDGLERLAGLNDTNLVEAHGTFASASCVRCGEDYSATQLKLK 757
I D+ + I + +KNI++MAGAGIS SGIPDFRSPGTGLYDNL++YK+PYP A+FD+DYF NPKPFF LAKEL+PSGKYRPN VHYF R L E+ LL R+YTQNIDGLERLAG+ LVEAHGTF SASC +CG+ Y+ +K K
Sbjct: 16 IEDVARIIKSEGVKNIIVMAGAGISTASGIPDFRSPGTGLYDNLQKYKVPYPTAVFDLDYFHSNPKPFFELAKELYPSGKYRPNAVHYFVRCLHERGLLLRMYTQNIDGLERLAGIPPMKLVEAHGTFTSASCTKCGKKYNGETIKDK 163 HSP 2 Score: 103.605 bits (257), Expect = 1.725e-20 Identity = 53/92 (57.61%), Postives = 64/92 (69.57%), Query Frame = 2
Query: 1115 CRGIVKPDIVFFGEDLPSKFHLFRSDFQQADLLLVMGTSLEVEPFASIVDSTRFGTPRVLINRQPVGVFRSKRRVHDNCVLGK-QTSVSELA 1387
C GI+KPDIVFFGEDLP +F+ + DF DLLLVMGTSL+VEPFAS+VDSTR TPR+L+N VG F R D + G S+ +LA
Sbjct: 178 CYGIIKPDIVFFGEDLPKRFYYYLKDFPACDLLLVMGTSLQVEPFASLVDSTRATTPRLLLNMVKVGPFTKPSRRTDLSITGDISDSIHKLA 269
BLAST of NAD-dependent protein deacetylase vs. TrEMBL
Match: A0A1S3JTY3 (NAD-dependent protein deacetylase sirtuin-3 OS=Lingula unguis OX=7574 GN=LOC106176139 PE=4 SV=1) HSP 1 Score: 224.557 bits (571), Expect = 4.014e-60 Identity = 100/144 (69.44%), Postives = 120/144 (83.33%), Query Frame = 2
Query: 320 DICQKILTSKIKNIVIMAGAGISCPSGIPDFRSPGTGLYDNLKQYKIPYPEAIFDIDYFLQNPKPFFALAKELFPSGKYRPNKVHYFFRLLQEKKLLRRVYTQNIDGLERLAGLNDTNLVEAHGTFASASCVRCGEDYSATQLK 751
D+ + I + KNIV+MAGAGIS PSGIPDFRSPGTGLYDNL+QY IPYPEAIFDIDYF NP+PFFAL+KEL+PSGKYRPN +HYF RLL +K LL R+YTQNIDGLERLAG+ LVEAHGTF++A+C+RC ++ ++K
Sbjct: 101 DVSRYIREGRAKNIVVMAGAGISTPSGIPDFRSPGTGLYDNLQQYNIPYPEAIFDIDYFHMNPRPFFALSKELYPSGKYRPNYIHYFMRLLHDKGLLHRMYTQNIDGLERLAGIPSEKLVEAHGTFSTATCIRCNLEHRGDEIK 244 HSP 2 Score: 114.005 bits (284), Expect = 1.128e-22 Identity = 55/87 (63.22%), Postives = 67/87 (77.01%), Query Frame = 2
Query: 1085 DKSEICYCSKCRGIVKPDIVFFGEDLPSKFHLFRSDFQQADLLLVMGTSLEVEPFASIVDSTRFGTPRVLINRQPVGVFRSKRRVHD 1345
DK C + C GIVKPDIVFFGE+LP +F+ + DF QADL+LV+GTSLEVEPFASIVD++R PRVL NR+ VG F+ KRR +D
Sbjct: 250 DKLPKCKKTNCLGIVKPDIVFFGEELPRRFYYYLKDFPQADLVLVLGTSLEVEPFASIVDASRSYIPRVLFNREAVGPFKRKRRNND 336
BLAST of NAD-dependent protein deacetylase vs. TrEMBL
Match: W4XPP2 (Deacetylase sirtuin-type domain-containing protein OS=Strongylocentrotus purpuratus OX=7668 PE=4 SV=1) HSP 1 Score: 226.868 bits (577), Expect = 5.543e-60 Identity = 108/166 (65.06%), Postives = 128/166 (77.11%), Query Frame = 2
Query: 257 SSTFGRYLSTPSGTDDQ-KFIVDICQKILTSKIKNIVIMAGAGISCPSGIPDFRSPGTGLYDNLKQYKIPYPEAIFDIDYFLQNPKPFFALAKELFPSGKYRPNKVHYFFRLLQEKKLLRRVYTQNIDGLERLAGLNDTNLVEAHGTFASASCVRCGEDYSATQLK 751
S+T R S+ +G K I D+ ++IL K KNIV+MAGAGIS PSGIPDFRSPG+GLYDNL+QY+IPYPEAIFDID+F +NPKPFF LAKEL+PSGKYRPN VHYF R+L EK LL R+YTQNIDGLERLAG+ LVEAHGTF +C +CG + +K
Sbjct: 166 SATPKRRQSSSAGNSSTFKTIEDVARRILQKKSKNIVVMAGAGISTPSGIPDFRSPGSGLYDNLQQYRIPYPEAIFDIDFFRKNPKPFFTLAKELYPSGKYRPNYVHYFVRMLYEKGLLLRMYTQNIDGLERLAGIPGDKLVEAHGTFTRCTCTKCGYQHEGEDVK 331 HSP 2 Score: 97.0561 bits (240), Expect = 6.841e-17 Identity = 52/94 (55.32%), Postives = 61/94 (64.89%), Query Frame = 2
Query: 1085 DKSEICYCSKCRGIVKPDIVFFGEDLPSKFHLFRSDFQQADLLLVMGTSLEVEPFASIVDSTRFGTPRVLINRQPVGVFR--SKRRVHDNCVLG 1360
DK C +C G+VKP+IVFFGEDLP +F + D DLL+VMGTSLEV PFA IVDS R PR+LINR+ VG F S R +D V G
Sbjct: 337 DKIPRCMRPRCTGVVKPNIVFFGEDLPKRFFYYMKDMPLCDLLIVMGTSLEVYPFAGIVDSVRPFVPRLLINREVVGPFSRPSSSRHNDLAVTG 430
BLAST of NAD-dependent protein deacetylase vs. TrEMBL
Match: H2ZB26 (NAD-dependent protein deacetylase OS=Ciona savignyi OX=51511 PE=3 SV=1) HSP 1 Score: 217.238 bits (552), Expect = 9.113e-60 Identity = 100/148 (67.57%), Postives = 119/148 (80.41%), Query Frame = 2
Query: 314 IVDICQKILTSKIKNIVIMAGAGISCPSGIPDFRSPGTGLYDNLKQYKIPYPEAIFDIDYFLQNPKPFFALAKELFPSGKYRPNKVHYFFRLLQEKKLLRRVYTQNIDGLERLAGLNDTNLVEAHGTFASASCVRCGEDYSATQLKLK 757
I D+ + I + +KNI++MAGAGIS SGIPDFRSPGTGLYDNL++YK+PYP A+FD+DYF NPKPFF LAKEL+PSGKYRPN VHYF R L E+ LL R+YTQNIDGLERLAG+ LVEAHGTF SASC +CG+ Y+ +K K
Sbjct: 1 IEDVARIIKSEGVKNIIVMAGAGISTASGIPDFRSPGTGLYDNLQKYKVPYPTAVFDLDYFHSNPKPFFELAKELYPSGKYRPNAVHYFVRCLHERGLLLRMYTQNIDGLERLAGIPPMKLVEAHGTFTSASCTKCGKKYNGETIKDK 148 HSP 2 Score: 90.5077 bits (223), Expect = 6.087e-16 Identity = 53/115 (46.09%), Postives = 65/115 (56.52%), Query Frame = 2
Query: 1115 CRGIVKPDIVFFGEDLPSKFHLFRSDFQQADLLLVMGTSLE-----------------------VEPFASIVDSTRFGTPRVLINRQPVGVFRSKRRVHDNCVLGKQT-SVSELA 1387
C GI+KPDIVFFGEDLP +F+ + DF DLLLVMGTSL+ VEPFAS+VDSTR TPR+L+N VG F R D + G + S+ +LA
Sbjct: 163 CYGIIKPDIVFFGEDLPKRFYYYLKDFPACDLLLVMGTSLQVRCYSLYFTAARITQCDFILSYFVEPFASLVDSTRATTPRLLLNMVKVGPFTKPSRRTDLSITGDISDSIHKLA 277
BLAST of NAD-dependent protein deacetylase vs. Ensembl Cavefish
Match: sirt3 (sirtuin 3 [Source:NCBI gene;Acc:103044645]) HSP 1 Score: 199.134 bits (505), Expect = 4.662e-56 Identity = 94/144 (65.28%), Postives = 112/144 (77.78%), Query Frame = 2
Query: 320 DICQKILTSKIKNIVIMAGAGISCPSGIPDFRSPGTGLYDNLKQYKIPYPEAIFDIDYFLQNPKPFFALAKELFPSGKYRPNKVHYFFRLLQEKKLLRRVYTQNIDGLERLAGLNDTNLVEAHGTFASASCVRCGEDYSATQLK 751
DI + I + K IV+MAGAGIS PSGIPDFRSPG+GLYDNL+QY +PY EAIF+I+YF NPKPFFALAKEL+P G Y+PN HYF RLL +K L R+YTQNIDGLER+AG+ LVEAHGTFA+A+C C DY +L+
Sbjct: 79 DIAKGIRDREYKRIVVMAGAGISTPSGIPDFRSPGSGLYDNLQQYNLPYAEAIFEINYFHHNPKPFFALAKELYP-GNYQPNLTHYFIRLLHDKGQLLRMYTQNIDGLERMAGIPPKMLVEAHGTFATATCTVCRRDYKGEELR 221 HSP 2 Score: 99.7525 bits (247), Expect = 5.097e-22 Identity = 54/114 (47.37%), Postives = 68/114 (59.65%), Query Frame = 2
Query: 1106 CSKCRGIVKPDIVFFGEDLPSKFHLFRSDFQQADLLLVMGTSLEVEPFASIVDSTRFGTPRVLINRQPVGVFRSKRRVHDNCVLGKQTSVSELAGTDCGRRSSALTLLQQPILE 1447
C C+G++KPDIVFFGE+LP F L+ +DF ADL++VMGTSLEVEPFAS+ + R R+LINR VG F H++ V+EL G R A L P LE
Sbjct: 232 CPHCKGVIKPDIVFFGEELPQHFFLYLTDFPIADLVIVMGTSLEVEPFASLAGAVRGSVSRLLINRDLVGPFAWGSPRHND--------VAELGDVVSGVRRLAEALGWMPELE 337
BLAST of NAD-dependent protein deacetylase vs. Ensembl Cavefish
Match: si:dkey-103i16.6 (si:dkey-103i16.6 [Source:ZFIN;Acc:ZDB-GENE-061207-46]) HSP 1 Score: 185.267 bits (469), Expect = 3.479e-52 Identity = 85/156 (54.49%), Postives = 117/156 (75.00%), Query Frame = 2
Query: 347 KIKNIVIMAGAGISCPSGIPDFRSPGTGLYDNLKQYKIPYPEAIFDIDYFLQNPKPFFALAKELFPSGKYRPNKVHYFFRLLQEKKLLRRVYTQNIDGLERLAGLNDTNLVEAHGTFASASCVRCGEDYSATQLKLKHSIS--EICEIFFIASVVL 808
+++N+V++AGAGIS SGIPDFR+PGTGLY NL++Y +PYPEA+F+IDYF +P+PFF+LAKEL+P G++RPN +HYF R+L +K LL R+YTQNIDGLE++ G+ D LVEAHG+FA+ASC C + + + + +I C SVV
Sbjct: 5 RLRNVVVVAGAGISTASGIPDFRTPGTGLYANLEKYNVPYPEAVFNIDYFSDDPRPFFSLAKELYP-GRHRPNYIHYFIRMLHQKGLLLRMYTQNIDGLEKMCGIPDDKLVEAHGSFATASCHLCYTPFPSEEAIMSDNIPTCSFCSATVKPSVVF 159 HSP 2 Score: 96.6709 bits (239), Expect = 1.255e-21 Identity = 63/160 (39.38%), Postives = 87/160 (54.37%), Query Frame = 2
Query: 929 HHRSFHPQLWVKNLNG--KMC*FP*---IINCGSLSKNSLSNISGPKASLIIYLESIDKSEICYCSKCRGIVKPDIVFFGEDLPSKFHLFRSDFQQADLLLVMGTSLEVEPFASIVDSTRFGTPRVLINRQPVGVF-RSKRRVHDNCVLGKQT-SVSELA 1387
H + +++ +N++G KMC P + GS + S P S E+I I CS C VKP +VFFGEDLP + DF +ADLL++MGTSL++EPFAS+V++ + PR+L+NR VG F R R D LG SV +LA
Sbjct: 86 HQKGLLLRMYTQNIDGLEKMCGIPDDKLVEAHGSFATASCHLCYTPFPSE----EAIMSDNIPTCSFCSATVKPSVVFFGEDLPETYFQHAQDFPKADLLIIMGTSLQIEPFASLVNTVKSTVPRLLLNRHAVGPFERKPLRRRDYLELGDLVHSVRKLA 241
BLAST of NAD-dependent protein deacetylase vs. Ensembl Cavefish
Match: si:dkey-103i16.6 (si:dkey-103i16.6 [Source:ZFIN;Acc:ZDB-GENE-061207-46]) HSP 1 Score: 187.963 bits (476), Expect = 1.704e-51 Identity = 81/135 (60.00%), Postives = 111/135 (82.22%), Query Frame = 2
Query: 347 KIKNIVIMAGAGISCPSGIPDFRSPGTGLYDNLKQYKIPYPEAIFDIDYFLQNPKPFFALAKELFPSGKYRPNKVHYFFRLLQEKKLLRRVYTQNIDGLERLAGLNDTNLVEAHGTFASASCVRCGEDYSATQLK 751
+++N+V++AGAGIS SGIPDFR+PGTGLY NL++Y +PYPEA+F+IDYF +P+PFF+LAKEL+P G++RPN +HYF R+L +K LL R+YTQNIDGLE++ G+ D LVEAHG+FA+ASC C + + + K
Sbjct: 120 RLRNVVVVAGAGISTASGIPDFRTPGTGLYANLEKYNVPYPEAVFNIDYFSDDPRPFFSLAKELYP-GRHRPNYIHYFIRMLHQKGLLLRMYTQNIDGLEKMCGIPDDKLVEAHGSFATASCHLCYTPFPSEEAK 253 HSP 2 Score: 95.1301 bits (235), Expect = 4.038e-20 Identity = 54/147 (36.73%), Postives = 78/147 (53.06%), Query Frame = 2
Query: 929 HHRSFHPQLWVKNLNG--KMC*FP*IINCGSLSKNSLSNISGPKASLIIYL-----------ESIDKSEICYCSKCRGIVKPDIVFFGEDLPSKFHLFRSDFQQADLLLVMGTSLEVEPFASIVDSTRFGTPRVLINRQPVGVFRSK 1330
H + +++ +N++G KMC P + L G A+ +L E+I I CS C VKP +VFFGEDLP + DF +ADLL++MGTSL++EPFAS+V++ + PR+L+NR VG F K
Sbjct: 201 HQKGLLLRMYTQNIDGLEKMCGIP---------DDKLVEAHGSFATASCHLCYTPFPSEEAKEAIMSDNIPTCSFCSATVKPSVVFFGEDLPETYFQHAQDFPKADLLIIMGTSLQIEPFASLVNTVKSTVPRLLLNRHAVGPFERK 338
BLAST of NAD-dependent protein deacetylase vs. Ensembl Cavefish
Match: sirt2 (sirtuin 2 [Source:NCBI gene;Acc:103038996]) HSP 1 Score: 185.652 bits (470), Expect = 5.015e-51 Identity = 92/177 (51.98%), Postives = 125/177 (70.62%), Query Frame = 2
Query: 239 NEMIYLSSTFGRYL--STPSGTDDQKFIVDICQKILTSKIKNIVIMAGAGISCPSGIPDFRSPGTGLYDNLKQYKIPYPEAIFDIDYFLQNPKPFFALAKELFPSGKYRPNKVHYFFRLLQEKKLLRRVYTQNIDGLERLAGLNDTNLVEAHGTFASASCVR--CGEDYSATQLKLK 757
+EM +L + F R L S D + + + I + K KNI+ M GAGIS +GIPDFRSPGTGLY NL++Y +PYPEAIF IDYF ++P+PFFALA+EL+P G+++P HYF R+L++K LLRR Y+QNID LER+AGL +L+EAHGTF ++ CV C ++Y+ +K K
Sbjct: 37 SEMDFLRNLFSRTLGLSPEEKVLDDLSLEGVARYIQSGKCKNIICMVGAGISTSAGIPDFRSPGTGLYANLQKYNLPYPEAIFQIDYFKKHPEPFFALARELYP-GQFKPTVCHYFIRMLKDKGLLRRCYSQNIDTLERVAGLEGEDLIEAHGTFHTSHCVSLFCRKEYTMDWMKEK 212 HSP 2 Score: 82.4185 bits (202), Expect = 3.614e-16 Identity = 40/81 (49.38%), Postives = 53/81 (65.43%), Query Frame = 2
Query: 1076 ESIDKSEICYCSKCRGIVKPDIVFFGEDLPSKF-HLFRSDFQQADLLLVMGTSLEVEPFASIVDSTRFGTPRVLINRQPVG 1315
E I +I C C +VKPDIVFFGE+LP++F + DF DLL++MGTSL+V+PFAS+V PR+LIN + G
Sbjct: 211 EKIFSEDIPKCDACNNLVKPDIVFFGENLPARFFTTMKKDFPHCDLLIIMGTSLQVQPFASLVSRVPNSCPRLLINMEKTG 291
BLAST of NAD-dependent protein deacetylase vs. Ensembl Cavefish
Match: ENSAMXT00000003809.2 (pep primary_assembly:Astyanax_mexicanus-2.0:25:45151234:45158481:-1 gene:ENSAMXG00000003731.2 transcript:ENSAMXT00000003809.2 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 120.168 bits (300), Expect = 2.738e-27 Identity = 59/125 (47.20%), Postives = 88/125 (70.40%), Query Frame = 2
Query: 353 KNIVIMAGAGISCPSGIPDFRSPGTGLYDNLKQ--YKIPYPEAIFDIDYFLQNPKPFFALAKELFPSGKYRPNKVHYFFRLLQEKKLLRRVYTQNIDGLERLAGLNDTNLVEAHGTFASASCVRC 721
K I+++ GAG+S GIPDFRS G+Y L +P P+A+FDIDYF ++P+PFF AKE++P G+++P+ H F +L +K+ L R YTQNID LE++AG+ +++ HG+FA+ASC+ C
Sbjct: 290 KKILVLTGAGVSVSCGIPDFRS-RDGIYARLAVDFPDLPDPQAMFDIDYFRRDPRPFFKFAKEIYP-GQFQPSLCHRFISMLDKKEKLLRNYTQNIDTLEQVAGVQ--KIIQCHGSFATASCLVC 410 HSP 2 Score: 72.4034 bits (176), Expect = 1.643e-12 Identity = 39/84 (46.43%), Postives = 52/84 (61.90%), Query Frame = 2
Query: 1076 ESIDKSEICYCSKCR----GIVKPDIVFFGEDLPSKFH-LFRSDFQQADLLLVMGTSLEVEPFASIVDSTRFGTPRVLINRQPV 1312
E I + + +C KC I+KPDIVFFGE+LP FH + D DLL+V+G+SL+V P A I S P+VLINR+P+
Sbjct: 421 EDIFRQVVPHCPKCPDIPFAIMKPDIVFFGENLPESFHRAMKQDKDAVDLLIVIGSSLKVRPVALIPSSVPHDVPQVLINREPL 504
BLAST of NAD-dependent protein deacetylase vs. Ensembl Sea Lamprey
Match: sirt2 (sirtuin 2 (silent mating type information regulation 2, homolog) 2 (S. cerevisiae) [Source:NCBI gene;Acc:322309]) HSP 1 Score: 187.963 bits (476), Expect = 8.791e-53 Identity = 89/171 (52.05%), Postives = 120/171 (70.18%), Query Frame = 2
Query: 254 LSSTFGRYLSTPSGTDDQKFIVD-----ICQKILTSKIKNIVIMAGAGISCPSGIPDFRSPGTGLYDNLKQYKIPYPEAIFDIDYFLQNPKPFFALAKELFPSGKYRPNKVHYFFRLLQEKKLLRRVYTQNIDGLERLAGLNDTNLVEAHGTFASASCVRCGEDYSATQLK 751
L R L S + ++ + + + + IL K KNIV M GAGIS +GIPDFRSPGTGLYDNL++Y +P+P+A+FDI YF +NP+PFFALAKEL+P G+++P HYF RLL++K+ L R YTQNID LER+AGL + LVEAHGTF ++ C+ C +Y + +K
Sbjct: 4 LREMLARKLELGSASGHERVLEELTLGGVAKHILAGKCKNIVCMVGAGISTAAGIPDFRSPGTGLYDNLQKYNLPHPQAVFDIGYFRENPEPFFALAKELYP-GQFKPTVSHYFIRLLKDKECLLRCYTQNIDTLERVAGLENNELVEAHGTFHTSHCLGCRHEYCLSWMK 173 HSP 2 Score: 83.1889 bits (204), Expect = 3.541e-17 Identity = 42/81 (51.85%), Postives = 54/81 (66.67%), Query Frame = 2
Query: 1076 ESIDKSEICYCSKCRGIVKPDIVFFGEDLPSKF-HLFRSDFQQADLLLVMGTSLEVEPFASIVDSTRFGTPRVLINRQPVG 1315
E I ++ C KC+ +VKPDIVFFGE LP KF +SDF + DLL++MGTSL V+PFAS+ TPR+LIN + G
Sbjct: 174 EQIFSDKVPRCEKCKSVVKPDIVFFGEALPEKFFTCVQSDFPKCDLLIIMGTSLVVQPFASLTSRVPDSTPRLLINLEKSG 254
BLAST of NAD-dependent protein deacetylase vs. Ensembl Sea Lamprey
Match: sirt3 (sirtuin 3 [Source:ZFIN;Acc:ZDB-GENE-070112-1762]) HSP 1 Score: 171.785 bits (434), Expect = 4.948e-48 Identity = 88/144 (61.11%), Postives = 112/144 (77.78%), Query Frame = 2
Query: 320 DICQKILTSKIKNIVIMAGAGISCPSGIPDFRSPGTGLYDNLKQYKIPYPEAIFDIDYFLQNPKPFFALAKELFPSGKYRPNKVHYFFRLLQEKKLLRRVYTQNIDGLERLAGLNDTNLVEAHGTFASASCVRCGEDYSATQLK 751
D+ + I KNIV+MAGAG+S SGIPDFR+PGTGLYDNL++Y +P+PEA+FD+D+F +PKPFF LA+EL+P G RPN HYF RLL E++LL R+YTQNIDGLER+AGL LVEAHGTFASA+C +C + Q++
Sbjct: 16 DVARLIRDGHCKNIVLMAGAGMSTASGIPDFRTPGTGLYDNLQRYHLPFPEAVFDLDFFAVDPKPFFTLAQELYP-GNCRPNDAHYFARLLHERRLLLRLYTQNIDGLERVAGLPPDMLVEAHGTFASATCTQCRKPQPGDQVR 158 HSP 2 Score: 103.605 bits (257), Expect = 1.774e-24 Identity = 50/112 (44.64%), Postives = 70/112 (62.50%), Query Frame = 2
Query: 1076 ESIDKSEICYCSKCRGIVKPDIVFFGEDLPSKFHLFRSDFQQADLLLVMGTSLEVEPFASIVDSTRFGTPRVLINRQPVGVFRSKRR-----VHDNCVLGKQTSVSELAGTD 1396
++ +I +C C +VKPDIVFFGEDLP +F+ + DF ADLL+V+GTSLEV PFA +V + R G PR+L+NR+ VG+FR H + V+ ++ L G D
Sbjct: 159 RTVMSGKIPHCGACSAVVKPDIVFFGEDLPRRFYAYDQDFSMADLLIVIGTSLEVMPFAGLVSAVRPGVPRLLLNREAVGLFRRAASSPTDVAHLDDVVAGVRRLTNLVGWD 270
BLAST of NAD-dependent protein deacetylase vs. Ensembl Sea Lamprey
Match: sirt4 (sirtuin 4 [Source:ZFIN;Acc:ZDB-GENE-041010-65]) HSP 1 Score: 67.781 bits (164), Expect = 2.421e-12 Identity = 51/176 (28.98%), Postives = 79/176 (44.89%), Query Frame = 2
Query: 272 RYLSTPSGTDDQKFIVDICQKILTSK----------IKNIVIMAGAGISCPSGIPDFRSPGTGLYDNLKQYKIPYPE----AIFDIDYFLQNPKPFFALAKELFPSGKYRPNKVHYFFRLLQEKKLLRRVYTQNIDGLERLAGLNDTNLVEAHGTFASASCVRCGEDYSATQLKLK 757
R+ S+P+ + D F V C T + + + ++AGAG+S SGIPD+RS G GLY + + + E A+ Y+ +N F + F S RPN H +++ L + TQN+D L AG + E HG C+ C E T+L+ +
Sbjct: 15 RWCSSPAASPDLAF-VPACAPAGTQQRGQLQDFLANSRRLFVLAGAGLSTESGIPDYRSEGVGLYARTSRRPMQHAEFARSAVARRRYWARN---FTGWPR--FSS--RRPNAAHLALGRWEQQGRLHWLVTQNVDALHAKAG--SRRITELHGCSHRVVCLDCKEVTQRTELQQR 180
BLAST of NAD-dependent protein deacetylase vs. Ensembl Sea Lamprey
Match: sirt6 (sirtuin 6 [Source:ZFIN;Acc:ZDB-GENE-031007-2]) HSP 1 Score: 59.3066 bits (142), Expect = 1.537e-9 Identity = 44/154 (28.57%), Postives = 67/154 (43.51%), Query Frame = 2
Query: 338 LTSKIKNIVIMAGAGISCPSGIPDFRSPGTGLYDNLKQYKIPYPEAIFDIDYFLQNPKPFFALAKELFPSGKYRPNKVHYFFRLLQEKKLLRRVYTQNIDGLERLAGLNDTNLVEAHGTFASASCVRCGE----DYSATQLKLKHSISEICEIF 787
L K +VI GAG+S +GIPDF G P ++ ++ PK F + E RP H L + LL+ + +QN+DGL +G L E HG C RCG+ D++ + LK++ +IC++
Sbjct: 40 LVRASKYMVIHTGAGVSTAAGIPDFSYRG--------------PNGVWTMEQKGLTPK--FNITFE-----DARPTATHMAMLGLYREGLLKHLVSQNVDGLHIRSGFPRDKLSELHGNMFIEECERCGKQYVRDHTVGTMGLKYT-GKICDVV 171
BLAST of NAD-dependent protein deacetylase vs. Ensembl Yeast
Match: HST2 (Cytoplasmic NAD(+)-dependent protein deacetylase; deacetylation targets are primarily cytoplasmic proteins; member of the silencing information regulator 2 (Sir2) family of NAD(+)-dependent protein deacetylases; modulates nucleolar (rDNA) and telomeric silencing; possesses NAD(+)-dependent histone deacetylase activity in vitro; contains a nuclear export signal (NES); function regulated by its nuclear export [Source:SGD;Acc:S000005936]) HSP 1 Score: 170.244 bits (430), Expect = 8.004e-47 Identity = 76/133 (57.14%), Postives = 98/133 (73.68%), Query Frame = 2
Query: 359 IVIMAGAGISCPSGIPDFRSPGTGLYDNLKQYKIPYPEAIFDIDYFLQNPKPFFALAKELFPSGKYRPNKVHYFFRLLQEKKLLRRVYTQNIDGLERLAGLNDTNLVEAHGTFASASCVRCGEDYSATQLKLK 757
++ M GAGIS GIPDFRSPGTGLY NL + K+PYPEA+FD+D+F +P PF+ LAKEL+P G +RP+K HY +L Q+K +L+RVYTQNID LER AG+ D ++EAHG+FA C+ CG+ Y K K
Sbjct: 27 VIFMVGAGISTSCGIPDFRSPGTGLYHNLARLKLPYPEAVFDVDFFQSDPLPFYTLAKELYP-GNFRPSKFHYLLKLFQDKDVLKRVYTQNIDTLERQAGVKDDLIIEAHGSFAHCHCIGCGKVYPPQVFKSK 158 HSP 2 Score: 60.077 bits (144), Expect = 6.267e-10 Identity = 37/94 (39.36%), Postives = 50/94 (53.19%), Query Frame = 2
Query: 1106 CSKCRGIVKPDIVFFGEDLPSKF-HLFRSDFQ-------------QADLLLVMGTSLEVEPFASIVDSTRFGTPRVLINRQPVGVFRSKRRVHD 1345
C C +VKP IVFFGEDLP F + +D + Q L++V+GTSL V PFAS+ + RVL N + VG F++ +R D
Sbjct: 170 CDVCGELVKPAIVFFGEDLPDSFSETWLNDSEWLREKITTSGKHPQQPLVIVVGTSLAVYPFASLPEEIPRKVKRVLCNLETVGDFKANKRPTD 263
BLAST of NAD-dependent protein deacetylase vs. Ensembl Yeast
Match: HST1 (NAD(+)-dependent histone deacetylase; essential subunit of the Sum1p/Rfm1p/Hst1p complex required for ORC-dependent silencing and meiotic repression; non-essential subunit of the Set3C deacetylase complex; involved in telomere maintenance; HST1 has a paralog, SIR2, that arose from the whole genome duplication [Source:SGD;Acc:S000005429]) HSP 1 Score: 112.079 bits (279), Expect = 3.704e-26 Identity = 55/124 (44.35%), Postives = 79/124 (63.71%), Query Frame = 2
Query: 353 KNIVIMAGAGISCPSGIPDFRSPGTGLYDNLKQYKIPYPEAIFDIDYFLQNPKPFFALAKELFP-SGKYRPNKVHYFFRLLQEKKLLRRVYTQNIDGLERLAGLNDTNLVEAHGTFASASCVRC 721
K I+++ GAG+S GIPDFRS G Y ++ + P+ +F++D FLQ+P F+ +A + P Y P +H F ++LQ+K L R YTQNID LE AG++ LV+ HG+FA+ASCV C
Sbjct: 201 KKILVLTGAGVSTSLGIPDFRS-SEGFYSKIRHLGLEDPQDVFNLDIFLQDPSVFYNIAHMVLPPENMYSP--LHSFIKMLQDKGKLLRNYTQNIDNLESYAGIDPDKLVQCHGSFATASCVTC 321 HSP 2 Score: 68.5514 bits (166), Expect = 2.590e-12 Identity = 33/68 (48.53%), Postives = 45/68 (66.18%), Query Frame = 2
Query: 1112 KCRGIVKPDIVFFGEDLPSKFH-LFRSDFQQADLLLVMGTSLEVEPFASIVDSTRFGTPRVLINRQPV 1312
K G++KPD+ FFGE LPS+FH R D + DLL+ +GTSL+V P + IV+ P++LINR V
Sbjct: 374 KSYGVLKPDMTFFGEALPSRFHKTIRKDILECDLLICIGTSLKVAPVSEIVNMVPSHVPQILINRDMV 441
BLAST of NAD-dependent protein deacetylase vs. Ensembl Yeast
Match: SIR2 (Conserved NAD+ dependent histone deacetylase of the Sirtuin family; deacetylation targets are primarily nuclear proteins; required for telomere hypercluster formation in quiescent yeast cells; involved in regulation of lifespan; plays roles in silencing at HML, HMR, telomeres, and rDNA; negatively regulates initiation of DNA replication; functions as regulator of autophagy like mammalian homolog SIRT1, and also of mitophagy [Source:SGD;Acc:S000002200]) HSP 1 Score: 105.916 bits (263), Expect = 4.835e-24 Identity = 57/139 (41.01%), Postives = 85/139 (61.15%), Query Frame = 2
Query: 311 FIVD-ICQKILTSKIKNIVIMAGAGISCPSGIPDFRSPGTGLYDNLKQYKIPYPEAIFDIDYFLQNPKPFFALAKELFPSGK-YRPNKVHYFFRLLQEKKLLRRVYTQNIDGLERLAGLNDTNLVEAHGTFASASCVRC 721
F +D QK+ T++ I+++ GAG+S GIPDFRS G Y +K + P+ +F+ + F+ +P F+ +A + P K Y P +H F ++LQ K L R YTQNID LE AG++ LV+ HG+FA+A+CV C
Sbjct: 242 FTIDHFIQKLHTAR--KILVLTGAGVSTSLGIPDFRS-SEGFYSKIKHLGLDDPQDVFNYNIFMHDPSVFYNIANMVLPPEKIYSP--LHSFIKMLQMKGKLLRNYTQNIDNLESYAGISTDKLVQCHGSFATATCVTC 375 HSP 2 Score: 76.2554 bits (186), Expect = 9.954e-15 Identity = 42/101 (41.58%), Postives = 56/101 (55.45%), Query Frame = 2
Query: 1103 YCSKCRGIVKPDIVFFGEDLPSKFH-LFRSDFQQADLLLVMGTSLEVEPFASIVDSTRFGTPRVLINRQPVGVFRSKRRVHDNCVLGKQTSVSELAGTDCG 1402
Y G++KPDI FFGE LP+KFH R D + DLL+ +GTSL+V P + IV+ P+VLINR PV K D +LG ++ + CG
Sbjct: 430 YILNSYGVLKPDITFFGEALPNKFHKSIREDILECDLLICIGTSLKVAPVSEIVNMVPSHVPQVLINRDPV-----KHAEFDLSLLGYCDDIAAMVAQKCG 525
BLAST of NAD-dependent protein deacetylase vs. Ensembl Yeast
Match: HST3 (Member of the Sir2 family of NAD(+)-dependent protein deacetylases; involved along with Hst4p in telomeric silencing, cell cycle progression, radiation resistance, genomic stability and short-chain fatty acid metabolism [Source:SGD;Acc:S000005551]) HSP 1 Score: 80.8777 bits (198), Expect = 2.378e-16 Identity = 53/154 (34.42%), Postives = 77/154 (50.00%), Query Frame = 2
Query: 344 SKIKNIVIMAGAGISCPSGIPDFRSPGTGLYDNLKQ-----YKIPYPEAIFDIDYFLQNPKP--FFALAKELFPSGKY-RPNKVHYFFRLLQEKKLLRRVYTQNIDGLERLAGLNDTN----------------LVEAHGTFASASCVRCGEDY 733
S+ + I + GAGISC +GIPDFRS GLYD +K+ + I +FDI F + K F + L+ + + +P K H F L+++ L R YTQNIDGLE GL +N +V+ HG + SC +C + +
Sbjct: 50 SRSRRIACLTGAGISCNAGIPDFRS-SDGLYDLVKKDCSQYWSIKSGREMFDISLFRDDFKISIFAKFMERLYSNVQLAKPTKTHKFIAHLKDRNKLLRCYTQNIDGLEESIGLTLSNRKLPLTSFSSHWKNLDVVQLHGDLKTLSCTKCFQTF 202
BLAST of NAD-dependent protein deacetylase vs. Ensembl Yeast
Match: HST4 (NAD(+)-dependent protein deacetylase; deacetylation targets are primarily mitochondrial proteins; involved along with Hst3p in silencing at telomeres, cell cycle progression, radiation resistance, genomic stability and short-chain fatty acid metabolism; accumulates in mitochondria in response to biotin starvation and may link biotin metabolism with energy homeostasis; member of the Sir2 family and may be the functional equivalent of human SIRT3 [Source:SGD;Acc:S000002599]) HSP 1 Score: 52.7582 bits (125), Expect = 1.813e-7 Identity = 43/139 (30.94%), Postives = 59/139 (42.45%), Query Frame = 2
Query: 353 KNIVIMAGAGISCPSGIPDFRSP-------GTGLYDNLKQYKIPYPEAIFDIDYFLQNPKPFFALAKELFPSGKYRPNKVHYFFRLLQEKKLLRRVYTQNIDGLERLAGLNDTNL---------VEAHGTFASASCVRC 721
K +V+++GAGIS +GIPDFRS G +L Y Y + + F Q F L+K +P K H L R+YTQNIDGL+ TN+ V+ HG+ C +C
Sbjct: 93 KRMVVVSGAGISVAAGIPDFRSSEGIFSTVNGGSGKDLFDYNRVYGDESMSLK-FNQLMVSLFRLSKNC------QPTKFHEMLNEFARDGRLLRLYTQNIDGLDTQLPHLSTNVPLAKPIPSTVQLHGSIKHMECNKC 224
BLAST of NAD-dependent protein deacetylase vs. Ensembl Nematostella
Match: EDO47672 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RLD5]) HSP 1 Score: 184.111 bits (466), Expect = 2.009e-51 Identity = 85/128 (66.41%), Postives = 101/128 (78.91%), Query Frame = 2
Query: 368 MAGAGISCPSGIPDFRSPGTGLYDNLKQYKIPYPEAIFDIDYFLQNPKPFFALAKELFPSGKYRPNKVHYFFRLLQEKKLLRRVYTQNIDGLERLAGLNDTNLVEAHGTFASASCVRCGEDYSATQLK 751
MAGAGIS PSGIPDFR+PGTGLYDNL++Y IP P AIFDI+YF +P+PFF LAK L+P G Y+PN VHYF +LL +K L R+YTQNIDGLERLAGL LVEAHGTF++ASC+ C Y Q++
Sbjct: 1 MAGAGISTPSGIPDFRTPGTGLYDNLQEYNIPEPTAIFDIEYFWYDPRPFFCLAKTLYP-GNYQPNYVHYFVKLLHDKGFLLRMYTQNIDGLERLAGLPAEKLVEAHGTFSTASCISCHHSYDGEQIR 127 HSP 2 Score: 108.227 bits (269), Expect = 1.939e-25 Identity = 58/109 (53.21%), Postives = 75/109 (68.81%), Query Frame = 2
Query: 1076 ESIDKSEICYCS--KCRGIVKPDIVFFGEDLPSKFHLFRSDFQQADLLLVMGTSLEVEPFASIVDSTRFGTPRVLINRQPVGVFRS--KRRVHDNCVLGK-QTSVSELA 1387
++I+ +I C KC+G++KPD+VFFGEDLP +F+ F DF++ DLLLVMGTSLEVEPFA IV+ TPRVLINR+ VG F +RR D + G +SV LA
Sbjct: 128 KTIENGDIPRCETIKCKGVIKPDVVFFGEDLPKRFYSFEIDFRKCDLLLVMGTSLEVEPFAGIVNEVSRSTPRVLINRESVGPFLHPWRRRPKDVVLKGDIVSSVKRLA 236
BLAST of NAD-dependent protein deacetylase vs. Ensembl Nematostella
Match: EDO46813 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RNW2]) HSP 1 Score: 165.622 bits (418), Expect = 2.217e-45 Identity = 81/143 (56.64%), Postives = 109/143 (76.22%), Query Frame = 2
Query: 323 ICQKILTSKIKNIVIMAGAGISCPSGIPDFRSPGTGLYDNLKQYKIPYPEAIFDIDYFLQNPKPFFALAKELFPSGKYRPNKVHYFFRLLQEKKLLRRVYTQNIDGLERLAGLNDTNLVEAHGTFASASCVRCGEDYSATQLK 751
+ I + K K+I++M GAGIS +GIPDFRSPGTGLYDNL++Y +PYPE+IF+I YF NP+PFFAL KEL+P G ++P HYF +LL +KKLL R YTQN+D LER+AG+ D LVEAHG+F +A C+ C ++Y+ ++
Sbjct: 33 VANYIKSGKCKHIIVMTGAGISTAAGIPDFRSPGTGLYDNLQKYNLPYPESIFEIGYFRSNPEPFFALCKELYP-GSFKPTMSHYFIKLLYDKKLLLRNYTQNVDTLERIAGVPDDLLVEAHGSFHTAHCIECKKEYTKEDVR 174 HSP 2 Score: 87.4261 bits (215), Expect = 1.139e-18 Identity = 39/71 (54.93%), Postives = 51/71 (71.83%), Query Frame = 2
Query: 1106 CSKCRGIVKPDIVFFGEDLPSKFH-LFRSDFQQADLLLVMGTSLEVEPFASIVDSTRFGTPRVLINRQPVG 1315
CS C G++KPDIVFFGE LP +FH L D DL+++MGTSL V+PFAS++D TPR+LIN++ G
Sbjct: 185 CSGCEGVIKPDIVFFGESLPGRFHRLVPQDMPHCDLIIIMGTSLAVQPFASLIDRVLATTPRLLINKEKCG 255
BLAST of NAD-dependent protein deacetylase vs. Ensembl Nematostella
Match: EDO48459 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RIU3]) HSP 1 Score: 158.303 bits (399), Expect = 4.364e-43 Identity = 75/153 (49.02%), Postives = 107/153 (69.93%), Query Frame = 2
Query: 299 DDQKFIVDICQKILTSKIKNIVIMAGAGISCPSGIPDFRSPGTGLYDNLKQYKIPYPEAIFDIDYFLQNPKPFFALAKELFPSGKYRPNKVHYFFRLLQEKKLLRRVYTQNIDGLERLAGLNDTNLVEAHGTFASASCVRCGEDYSATQLKLK 757
DD F I + I + K KNIV++ GAGIS +GIPDFR+PG+GL++ L+ Y + +IF+IDYF NPKPFF AK ++P G+++P HYF +LLQ K LL R YTQNID LER+AG+ +L+EAHG+F + C+ C ++YS ++++
Sbjct: 2 DDVSF-EGIARYITSGKCKNIVVLTGAGISTTAGIPDFRTPGSGLFNVLQTYGLTTARSIFEIDYFQMNPKPFFVAAKAVYP-GQFKPTISHYFIKLLQNKGLLLRHYTQNIDTLERVAGITGDHLMEAHGSFHTGHCMACNKEYSQDWIRVE 152 HSP 2 Score: 83.1889 bits (204), Expect = 2.544e-17 Identity = 41/79 (51.90%), Postives = 55/79 (69.62%), Query Frame = 2
Query: 1082 IDKSEICYCSKCRGIVKPDIVFFGEDLPSKFH-LFRSDFQQADLLLVMGTSLEVEPFASIVDSTRFGTPRVLINRQPVG 1315
I +I C++C G+VKPDI FFG+ +P KF+ L DF + DLL+VMGTSL V+PFAS++ TPR+LINR+ G
Sbjct: 153 IMADKIPRCTECDGVVKPDIGFFGDPMPDKFYQLAAEDFPKCDLLIVMGTSLIVQPFASLIARVSVDTPRLLINREKCG 231
BLAST of NAD-dependent protein deacetylase vs. Ensembl Nematostella
Match: EDO31684 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SX90]) HSP 1 Score: 128.642 bits (322), Expect = 1.231e-32 Identity = 66/140 (47.14%), Postives = 94/140 (67.14%), Query Frame = 2
Query: 338 LTSKIKNIVIMAGAGISCPSGIPDFRSPGTGLYDNLK-QY-KIPYPEAIFDIDYFLQNPKPFFALAKELFPSGKYRPNKVHYFFRLLQEKKLLRRVYTQNIDGLERLAGLNDTNLVEAHGTFASASCVRCGEDYSATQLK 751
L K KNI+++ GAG+S GIPDFRS G+Y L +Y +P P+A+FDI YF QNPKPFF AKE++P G+++P+ H F L+E L R Y+QNID LE++AG+ T +++ HG+F++ASC+RC +K
Sbjct: 65 LIKKCKNIIVLTGAGVSVSCGIPDFRS-RDGIYAKLSVEYPDLPDPQAMFDITYFNQNPKPFFKFAKEIYP-GQFKPSLCHRFIHQLEEHGHLLRNYSQNIDTLEQVAGI--TRVIQCHGSFSTASCMRCKHKVPCEAIK 200 HSP 2 Score: 68.5514 bits (166), Expect = 2.397e-12 Identity = 39/86 (45.35%), Postives = 51/86 (59.30%), Query Frame = 2
Query: 1076 ESIDKSEICYCSKCR------GIVKPDIVFFGEDLPSKFHL-FRSDFQQADLLLVMGTSLEVEPFASIVDSTRFGTPRVLINRQPV 1312
E I + I CS C I+KPDIVFFGE LPS F+ D +ADLL+V+G+SL+V P A I P++LINR+P+
Sbjct: 201 EDIFRKNIPVCSTCSPDEEFPSIMKPDIVFFGESLPSNFYTHLGDDSNKADLLIVIGSSLKVRPVALIPSHISPEVPQILINREPL 286
BLAST of NAD-dependent protein deacetylase vs. Ensembl Nematostella
Match: EDO35866 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SK95]) HSP 1 Score: 66.2402 bits (160), Expect = 1.477e-11 Identity = 44/137 (32.12%), Postives = 65/137 (47.45%), Query Frame = 2
Query: 359 IVIMAGAGISCPSGIPDFRSPGTGLY----DNLKQYKIPYPEAIFDIDYFLQN--PKPFFALAKELFPSGKYRPNKVHYFFRLLQEKKLLRRVYTQNIDGLERLAGLNDTNLVEAHGTFASASCVRCGEDYSATQLK 751
I ++ GAGIS SGI D+RS G GLY D +Y++ A+ Y+ +N P F G +PN+ HY L+ + + TQN+D L AG N++E HG C+ C + + T L+
Sbjct: 63 IFVITGAGISTESGIRDYRSEGKGLYAITNDRPMEYQVFLKSAVMRQRYWARNYVGWPEF---------GSRQPNEAHYALAKLETLGSVHSLVTQNVDALHTKAG--SKNVIELHGCSHRVICLGCNQITARTALQ 188
BLAST of NAD-dependent protein deacetylase vs. Ensembl Medaka
Match: sirt3 (sirtuin 3 [Source:NCBI gene;Acc:101161471]) HSP 1 Score: 192.971 bits (489), Expect = 4.232e-54 Identity = 90/149 (60.40%), Postives = 112/149 (75.17%), Query Frame = 2
Query: 305 QKFIVDICQKILTSKIKNIVIMAGAGISCPSGIPDFRSPGTGLYDNLKQYKIPYPEAIFDIDYFLQNPKPFFALAKELFPSGKYRPNKVHYFFRLLQEKKLLRRVYTQNIDGLERLAGLNDTNLVEAHGTFASASCVRCGEDYSATQLK 751
Q + DI + + + K +V+MAGAGIS PSGIPDFRSPG+GLYDNL+QY +PY EAIF+I +F +NP PFFALAKEL+P G YRPN H+F LL +K L R+YTQNIDGLERLAG+ LVEAHGTFA+A+C C + Y +L+
Sbjct: 65 QLTLQDIARSLRDRQHKRVVVMAGAGISTPSGIPDFRSPGSGLYDNLQQYDLPYAEAIFEIGFFHRNPAPFFALAKELYP-GNYRPNPTHFFVHLLHQKGQLLRMYTQNIDGLERLAGIPPEKLVEAHGTFATATCTSCLQKYKGEELR 212 HSP 2 Score: 107.842 bits (268), Expect = 6.645e-25 Identity = 51/95 (53.68%), Postives = 64/95 (67.37%), Query Frame = 2
Query: 1079 SIDKSEICYCSKCRGIVKPDIVFFGEDLPSKFHLFRSDFQQADLLLVMGTSLEVEPFASIVDSTRFGTPRVLINRQPVGVFRSKRRVHDNCVLGK 1363
++ + CS C G+VKPDIVFFGE+LP F + +DF ADLL++MGTSLEVEPFAS+ + R PR+LINR PVG F RR D LG+
Sbjct: 214 AVMSGSVPKCSACGGVVKPDIVFFGEELPPHFLKYLTDFPLADLLIIMGTSLEVEPFASLAGAVRSSVPRLLINRDPVGPFVWGRRPQDVLQLGE 308
BLAST of NAD-dependent protein deacetylase vs. Ensembl Medaka
Match: si:dkey-103i16.6 (NAD-dependent protein deacetylase sirtuin-3, mitochondrial [Source:NCBI gene;Acc:101165477]) HSP 1 Score: 187.963 bits (476), Expect = 1.607e-51 Identity = 85/146 (58.22%), Postives = 112/146 (76.71%), Query Frame = 2
Query: 314 IVDICQKILTSKIKNIVIMAGAGISCPSGIPDFRSPGTGLYDNLKQYKIPYPEAIFDIDYFLQNPKPFFALAKELFPSGKYRPNKVHYFFRLLQEKKLLRRVYTQNIDGLERLAGLNDTNLVEAHGTFASASCVRCGEDYSATQLK 751
++ + + + + KN+V++AGAGIS SGIPDFR+PGTGLY NL++Y +PYPEAIF+IDYF NP+PFF+LAK L+P G +RPN +HYF R+L K LL R+YTQNIDGLE+L G+ D LVEAHG+FA+ASC C Y A + +
Sbjct: 107 LLSVARLVKLGRCKNVVVVAGAGISTASGIPDFRTPGTGLYSNLEKYNVPYPEAIFNIDYFSDNPQPFFSLAKVLYP-GSHRPNYIHYFIRVLHHKGLLLRMYTQNIDGLEKLCGIPDDKLVEAHGSFATASCHLCYTPYPAEEAR 251 HSP 2 Score: 103.99 bits (258), Expect = 4.374e-23 Identity = 64/151 (42.38%), Postives = 88/151 (58.28%), Query Frame = 2
Query: 929 HHRSFHPQLWVKNLNG--KMC*FP*---IINCGSLSKNSLSNISGP-KASLIIYLESIDKSEICYCSKCRGIVKPDIVFFGEDLPSKFHLFRSDFQQADLLLVMGTSLEVEPFASIVDSTRFGTPRVLINRQPVGVF-RSKRRVHDNCVLG 1360
HH+ +++ +N++G K+C P + GS + S P A Y +I + CS C VKPD+VFFGEDLP K+ L R DF +ADLL++MGTSL++EPFAS+V+S R PR+L+NR VG F R R D+ LG
Sbjct: 199 HHKGLLLRMYTQNIDGLEKLCGIPDDKLVEAHGSFATASCHLCYTPYPAEEARY--AIMHDRVPTCSFCTATVKPDVVFFGEDLPRKYFLHRKDFPKADLLIIMGTSLKIEPFASLVNSVRSTVPRLLLNRNAVGPFERVPLRRGDHMELG 347
BLAST of NAD-dependent protein deacetylase vs. Ensembl Medaka
Match: sirt3 (sirtuin 3 [Source:NCBI gene;Acc:101161471]) HSP 1 Score: 182.956 bits (463), Expect = 2.054e-51 Identity = 85/128 (66.41%), Postives = 101/128 (78.91%), Query Frame = 2
Query: 368 MAGAGISCPSGIPDFRSPGTGLYDNLKQYKIPYPEAIFDIDYFLQNPKPFFALAKELFPSGKYRPNKVHYFFRLLQEKKLLRRVYTQNIDGLERLAGLNDTNLVEAHGTFASASCVRCGEDYSATQLK 751
MAGAGIS PSGIPDFRSPG+GLYDNL+QY +PY EAIF+I +F +NP PFFALAKEL+P G YRPN H+F LL +K L R+YTQNIDGLERLAG+ LVEAHGTFA+A+C C + Y +L+
Sbjct: 1 MAGAGISTPSGIPDFRSPGSGLYDNLQQYDLPYAEAIFEIGFFHRNPAPFFALAKELYP-GNYRPNPTHFFVHLLHQKGQLLRMYTQNIDGLERLAGIPPEKLVEAHGTFATATCTSCLQKYKGEELR 127 HSP 2 Score: 107.842 bits (268), Expect = 1.778e-25 Identity = 51/95 (53.68%), Postives = 64/95 (67.37%), Query Frame = 2
Query: 1079 SIDKSEICYCSKCRGIVKPDIVFFGEDLPSKFHLFRSDFQQADLLLVMGTSLEVEPFASIVDSTRFGTPRVLINRQPVGVFRSKRRVHDNCVLGK 1363
++ + CS C G+VKPDIVFFGE+LP F + +DF ADLL++MGTSLEVEPFAS+ + R PR+LINR PVG F RR D LG+
Sbjct: 129 AVMSGSVPKCSACGGVVKPDIVFFGEELPPHFLKYLTDFPLADLLIIMGTSLEVEPFASLAGAVRSSVPRLLINRDPVGPFVWGRRPQDVLQLGE 223
BLAST of NAD-dependent protein deacetylase vs. Ensembl Medaka
Match: sirt2 (sirtuin 2 [Source:NCBI gene;Acc:101155450]) HSP 1 Score: 181.415 bits (459), Expect = 1.080e-49 Identity = 93/176 (52.84%), Postives = 120/176 (68.18%), Query Frame = 2
Query: 242 EMIYLSSTFGRYLSTPSGTD--DQKFIVDICQKILTSKIKNIVIMAGAGISCPSGIPDFRSPGTGLYDNLKQYKIPYPEAIFDIDYFLQNPKPFFALAKELFPSGKYRPNKVHYFFRLLQEKKLLRRVYTQNIDGLERLAGLNDTNLVEAHGTFASASCVR--CGEDYSATQLKLK 757
EM +L + F L S D + + Q I + K KNI+ M GAGIS +GIPDFRSP TGLY NL++Y +PYPEAIF IDYF ++P+PFF LAKEL+P G+++P HYF +LL+ K LLRR YTQNID LER+AGL +L+EAHGTF ++ CV C ++YS +K K
Sbjct: 37 EMDFLRNLFSSTLGLGSAEKVLDALTLEGVAQYIKSGKCKNIICMVGAGISTSAGIPDFRSPETGLYANLQKYNLPYPEAIFQIDYFKKHPEPFFTLAKELYP-GQFKPTICHYFIKLLKNKGLLRRCYTQNIDTLERVAGLEKEDLIEAHGTFYTSHCVSFCCRKEYSLDWMKEK 211 HSP 2 Score: 83.1889 bits (204), Expect = 1.884e-16 Identity = 43/87 (49.43%), Postives = 55/87 (63.22%), Query Frame = 2
Query: 1058 SLIIYLESIDKSEICYCSKCRGIVKPDIVFFGEDLPSKFHL-FRSDFQQADLLLVMGTSLEVEPFASIVDSTRFGTPRVLINRQPVG 1315
SL E I I C KC +VKPDIVFFGE+LP++F + DF + DLL+VMGTSL+V+PFA +V PR+LIN + G
Sbjct: 204 SLDWMKEKIFSDAIPKCEKCNSLVKPDIVFFGENLPARFFTSVKMDFPRCDLLIVMGTSLQVQPFAGLVGRVSKSCPRLLINMEKAG 290
BLAST of NAD-dependent protein deacetylase vs. Ensembl Medaka
Match: sirt2 (sirtuin 2 [Source:NCBI gene;Acc:101155450]) HSP 1 Score: 180.259 bits (456), Expect = 2.679e-49 Identity = 92/170 (54.12%), Postives = 118/170 (69.41%), Query Frame = 2
Query: 254 LSSTFGRYLSTPSGTDDQKFIVDICQKILTSKIKNIVIMAGAGISCPSGIPDFRSPGTGLYDNLKQYKIPYPEAIFDIDYFLQNPKPFFALAKELFPSGKYRPNKVHYFFRLLQEKKLLRRVYTQNIDGLERLAGLNDTNLVEAHGTFASASCVR--CGEDYSATQLKLK 757
SST G L + D + + Q I + K KNI+ M GAGIS +GIPDFRSP TGLY NL++Y +PYPEAIF IDYF ++P+PFF LAKEL+P G+++P HYF +LL+ K LLRR YTQNID LER+AGL +L+EAHGTF ++ CV C ++YS +K K
Sbjct: 29 FSSTLG--LGSAEKVLDALTLEGVAQYIKSGKCKNIICMVGAGISTSAGIPDFRSPETGLYANLQKYNLPYPEAIFQIDYFKKHPEPFFTLAKELYP-GQFKPTICHYFIKLLKNKGLLRRCYTQNIDTLERVAGLEKEDLIEAHGTFYTSHCVSFCCRKEYSLDWMKEK 195 HSP 2 Score: 75.8702 bits (185), Expect = 4.814e-14 Identity = 41/75 (54.67%), Postives = 51/75 (68.00%), Query Frame = 2
Query: 1058 SLIIYLESIDKSEICYCSKCRGIVKPDIVFFGEDLPSKFHLFRSDFQQADLLLVMGTSLEVEPFASIVDSTRFGT 1282
SL E I I C KC +VKPDIVFFGE+LP++F F SDF + DLL+VMGTSL+V+PFA +V R+G
Sbjct: 188 SLDWMKEKIFSDAIPKCEKCNSLVKPDIVFFGENLPARF--FTSDFPRCDLLIVMGTSLQVQPFAGLVG--RYGV 258
BLAST of NAD-dependent protein deacetylase vs. Planmine SMEST
Match: SMESG000079800.1 (SMESG000079800.1) HSP 1 Score: 486.878 bits (1252), Expect = 7.686e-162 Identity = 274/309 (88.67%), Postives = 275/309 (89.00%), Query Frame = 2
Query: 2207 DIVKAQTQLEVIAVDXXXXXXXXXXXXXXXXXXXSINSDFLSKLILYEEKFQIIEKSMKQYGKSNDQKASKSGNDQTKWENEMIKSLKLMYENQINFLTEEKERMNKIIFGLKHELEIVKEEARQAVHEFMIKKNMFEELQFNF*TKYRKTRLLFIDSFAPVQV*LRSK*YEYLNIKYEGLEMNFIKNLDQLNSIQISVTVNNLELKNLRHKEAHWKSQCNQAQLSFSRLSNDWILLQADNNEIKRQIEILKNSLEKSESHNKSLQTEIFKLQSKINCLENEKKIESFNSRCANRPKIYESPLITTFDQ 3133
DIVKAQTQLEVIAVDLKEKEEELNNIILENIELKSINSDFLSKLILYEEKFQIIEKSMKQYGKSNDQKASKSGNDQTKWENEMIKSLKLMYENQINFLTEEKERMNKIIFGLKHELEIVKEEARQAVHEFMIKKNMFEELQ IKYEGLEMNFIKNLDQLNSIQISVTVNNLELKNLRHKEAHWKSQCNQAQLSFS+LSNDWILLQADNNEIKRQIEILKNSLEKSESHNKSLQTEIFKLQSKINCLENEKKIESFNSRCANRPKIYESPLITTFDQ
Sbjct: 35 DIVKAQTQLEVIAVDLKEKEEELNNIILENIELKSINSDFLSKLILYEEKFQIIEKSMKQYGKSNDQKASKSGNDQTKWENEMIKSLKLMYENQINFLTEEKERMNKIIFGLKHELEIVKEEARQAVHEFMIKKNMFEELQ----------------------------------IKYEGLEMNFIKNLDQLNSIQISVTVNNLELKNLRHKEAHWKSQCNQAQLSFSKLSNDWILLQADNNEIKRQIEILKNSLEKSESHNKSLQTEIFKLQSKINCLENEKKIESFNSRCANRPKIYESPLITTFDQ 309
BLAST of NAD-dependent protein deacetylase vs. Planmine SMEST
Match: SMESG000079803.1 (SMESG000079803.1) HSP 1 Score: 351.673 bits (901), Expect = 2.613e-110 Identity = 168/173 (97.11%), Postives = 168/173 (97.11%), Query Frame = 2
Query: 260 STFGRYLSTPSGTDDQKFIVDICQKILTSKIKNIVIMAGAGISCPSGIPDFRSPGTGLYDNLKQYKIPYPEAIFDIDYFLQNPKPFFALAKELFPSGKYRPNKVHYFFRLLQEKKLLRRVYTQNIDGLERLAGLNDTNLVEAHGTFASASCVRCGEDYSATQLKLKHSISEIC 778
STFGRYLSTPSGTDDQKFIVDICQKILTSKIKNIVIMAGAGISCPSGIPDFRSPGTGLYDNLKQYKIPYPEAIFDIDYFLQNPKPFFALAKELFPSGKYRPNKVHYFFRLLQEKKLLRRVYTQNIDGLERLAGLNDTNLVEAHGTFASASCVRCGEDYSATQLK SEIC
Sbjct: 125 STFGRYLSTPSGTDDQKFIVDICQKILTSKIKNIVIMAGAGISCPSGIPDFRSPGTGLYDNLKQYKIPYPEAIFDIDYFLQNPKPFFALAKELFPSGKYRPNKVHYFFRLLQEKKLLRRVYTQNIDGLERLAGLNDTNLVEAHGTFASASCVRCGEDYSATQLKESIDKSEIC 297 HSP 2 Score: 203.756 bits (517), Expect = 1.931e-56 Identity = 95/95 (100.00%), Postives = 95/95 (100.00%), Query Frame = 2
Query: 1076 ESIDKSEICYCSKCRGIVKPDIVFFGEDLPSKFHLFRSDFQQADLLLVMGTSLEVEPFASIVDSTRFGTPRVLINRQPVGVFRSKRRVHDNCVLG 1360
ESIDKSEICYCSKCRGIVKPDIVFFGEDLPSKFHLFRSDFQQADLLLVMGTSLEVEPFASIVDSTRFGTPRVLINRQPVGVFRSKRRVHDNCVLG
Sbjct: 289 ESIDKSEICYCSKCRGIVKPDIVFFGEDLPSKFHLFRSDFQQADLLLVMGTSLEVEPFASIVDSTRFGTPRVLINRQPVGVFRSKRRVHDNCVLG 383
BLAST of NAD-dependent protein deacetylase vs. Planmine SMEST
Match: SMESG000079103.1 (SMESG000079103.1) HSP 1 Score: 126.331 bits (316), Expect = 6.613e-30 Identity = 62/125 (49.60%), Postives = 89/125 (71.20%), Query Frame = 2
Query: 353 KNIVIMAGAGISCPSGIPDFRSPGTGLYDNLKQY--KIPYPEAIFDIDYFLQNPKPFFALAKELFPSGKYRPNKVHYFFRLLQEKKLLRRVYTQNIDGLERLAGLNDTNLVEAHGTFASASCVRC 721
KNI+++ GAGIS P G+PDFRS G+Y L + P+++FDI YF +NPKPFF AKE++P GK+ P+ H F ++L++K L R Y+QNID LE++AG+ N++ HG+FASA+C+RC
Sbjct: 107 KNIMVLTGAGISVPCGVPDFRS-RNGIYARLAVDFPDLDEPQSMFDIHYFSKNPKPFFKFAKEIYP-GKFTPSFGHRFIKVLEDKGKLLRNYSQNIDTLEQIAGI--KNIIHCHGSFASATCMRC 227 HSP 2 Score: 59.6918 bits (143), Expect = 7.745e-9 Identity = 30/62 (48.39%), Postives = 40/62 (64.52%), Query Frame = 2
Query: 1124 IVKPDIVFFGEDLPSKFHL-FRSDFQQADLLLVMGTSLEVEPFASIVDSTRFGTPRVLINRQ 1306
I+KPD+VFFGE LP FH D Q DLL+V+G+SL+V P A I P++LIN++
Sbjct: 278 IMKPDVVFFGEGLPKDFHAKLSEDKDQVDLLIVIGSSLKVRPVAHIPGCLPPNIPQILINKE 339
BLAST of NAD-dependent protein deacetylase vs. Planmine SMEST
Match: SMESG000079103.1 (SMESG000079103.1) HSP 1 Score: 125.946 bits (315), Expect = 6.780e-30 Identity = 62/125 (49.60%), Postives = 89/125 (71.20%), Query Frame = 2
Query: 353 KNIVIMAGAGISCPSGIPDFRSPGTGLYDNLKQY--KIPYPEAIFDIDYFLQNPKPFFALAKELFPSGKYRPNKVHYFFRLLQEKKLLRRVYTQNIDGLERLAGLNDTNLVEAHGTFASASCVRC 721
KNI+++ GAGIS P G+PDFRS G+Y L + P+++FDI YF +NPKPFF AKE++P GK+ P+ H F ++L++K L R Y+QNID LE++AG+ N++ HG+FASA+C+RC
Sbjct: 98 KNIMVLTGAGISVPCGVPDFRS-RNGIYARLAVDFPDLDEPQSMFDIHYFSKNPKPFFKFAKEIYP-GKFTPSFGHRFIKVLEDKGKLLRNYSQNIDTLEQIAGI--KNIIHCHGSFASATCMRC 218 HSP 2 Score: 59.6918 bits (143), Expect = 7.906e-9 Identity = 30/62 (48.39%), Postives = 40/62 (64.52%), Query Frame = 2
Query: 1124 IVKPDIVFFGEDLPSKFHL-FRSDFQQADLLLVMGTSLEVEPFASIVDSTRFGTPRVLINRQ 1306
I+KPD+VFFGE LP FH D Q DLL+V+G+SL+V P A I P++LIN++
Sbjct: 269 IMKPDVVFFGEGLPKDFHAKLSEDKDQVDLLIVIGSSLKVRPVAHIPGCLPPNIPQILINKE 330
BLAST of NAD-dependent protein deacetylase vs. Planmine SMEST
Match: SMESG000062887.1 (SMESG000062887.1) HSP 1 Score: 98.9821 bits (245), Expect = 2.486e-22 Identity = 65/147 (44.22%), Postives = 89/147 (60.54%), Query Frame = 2
Query: 314 IVDICQKILTSKIKNIVIMAGAGISCPSGIPDFRSPGTGLYDNLK-QYKIPYPEAIFDIDYFLQNPKPFFALAKELFPSGKYRPNKVHYFFRLLQEKKLLRRVYTQNIDGLERLAGLNDTNLVEAHGTFASASCVRCGEDYSATQLK 751
++DI + I +++ K IV GAGIS +GIPDFRS GLY+ +K + +P PE IFDI YF +P F +AK+ F Y P H F +LL KKLL R +TQNIDGL+ G+ D +E HG F + C+ C + YS ++K
Sbjct: 30 LIDIIEIIRSNESK-IVTFTGAGISTSAGIPDFRSEN-GLYNIVKSKLNMPNPELIFDISYFEIDPTMFCCIAKQ-FIQNDYYPTLTHCFLKLLHNKKLLLRNFTQNIDGLDSKVGIPDDINIECHGHFKTGHCLSCEKLYSYEEMK 173 HSP 2 Score: 68.5514 bits (166), Expect = 3.838e-12 Identity = 34/73 (46.58%), Postives = 44/73 (60.27%), Query Frame = 2
Query: 1100 CYCSKCRGIVKPDIVFFGEDLPSKFHLFRSDFQQADLLLVMGTSLEVEPFASIVDSTRFGTPRVLI-NRQPVG 1315
C C G+VKPDIV FGE LP K + +ADL++VMG+SL V PF ++ R TP ++I N QP G
Sbjct: 184 CQAENCNGLVKPDIVLFGESLPKKVFENLNKISKADLIIVMGSSLRVTPFNQFINLARKETPLLVINNEQPSG 256 The following BLAST results are available for this feature:
BLAST of NAD-dependent protein deacetylase vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of NAD-dependent protein deacetylase vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of NAD-dependent protein deacetylase vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of NAD-dependent protein deacetylase vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of NAD-dependent protein deacetylase vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of NAD-dependent protein deacetylase vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of NAD-dependent protein deacetylase vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of NAD-dependent protein deacetylase vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of NAD-dependent protein deacetylase vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of NAD-dependent protein deacetylase vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 4
BLAST of NAD-dependent protein deacetylase vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 5
BLAST of NAD-dependent protein deacetylase vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of NAD-dependent protein deacetylase vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of NAD-dependent protein deacetylase vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30027733 ID=SMED30027733|Name=NAD-dependent protein deacetylase|organism=Schmidtea mediterranea sexual|type=transcript|length=3133bpback to top protein sequence of SMED30027733-orf-1 >SMED30027733-orf-1 ID=SMED30027733-orf-1|Name=SMED30027733-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=165bp MMGLANPIEQLNIENLQNQNDIVKAQTQLEVIAVDLKEKEEELNNIILENback to top protein sequence of SMED30027733-orf-2 >SMED30027733-orf-2 ID=SMED30027733-orf-2|Name=SMED30027733-orf-2|organism=Schmidtea mediterranea sexual|type=polypeptide|length=127bp MNFIKNLDQLNSIQISVTVNNLELKNLRHKEAHWKSQCNQAQLSFSRLSNback to top protein sequence of SMED30027733-orf-3 >SMED30027733-orf-3 ID=SMED30027733-orf-3|Name=SMED30027733-orf-3|organism=Schmidtea mediterranea sexual|type=polypeptide|length=193bp MIYLSSTFGRYLSTPSGTDDQKFIVDICQKILTSKIKNIVIMAGAGISCPback to top protein sequence of SMED30027733-orf-4 >SMED30027733-orf-4 ID=SMED30027733-orf-4|Name=SMED30027733-orf-4|organism=Schmidtea mediterranea sexual|type=polypeptide|length=131bp MDRAADQTSRKNDKILSGPTRSCRVDAHKYPGDCNNINDKIPNGNYEKNNback to top Annotated Terms
The following terms have been associated with this transcript:
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