Ras-related protein Rab-3

Overview
NameRas-related protein Rab-3
Smed IDSMED30027710
Length (bp)1090
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Ras-related protein Rab-3 (SMED30027710) t-SNE clustered cells

Violin plots show distribution of expression levels for Ras-related protein Rab-3 (SMED30027710) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Ras-related protein Rab-3 (SMED30027710) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Ras-related protein Rab-3 (SMED30027710) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30027710

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 11

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
head regionSMED30027710h1SMcG0004292 SmedASXL_006038SmedAsxl_ww_GCZZ01PMID:27034770
Currie et al., 2016		whole organism asexual adult RNA-sequencing evidence
Smed sexual biotypeSMED30027710h1SMcG0004292 Contig38967newmark_estsPMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30027710h1SMcG0004292 Contig38967uc_Smed_v2PMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
nervous systemSMED30027710h1SMcG0004292 dd_Smed_v4_7977_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30027710h1SMcG0004292 dd_Smed_v4_7977_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
neuronSMED30027710h1SMcG0004292 dd_Smed_v4_7977_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		whole organism asexual adult colorimetric in situ hybridization evidence
neoblastSMED30027710h1SMcG0004292 dd_Smed_v4_7977_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30027710h1SMcG0004292 Contig9267uc_Smed_v2PMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30027710h1SMcG0004292 Contig9267newmark_estsPMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
head regionSMED30027710h1SMcG0004292 dd_Smed_v6_7977_0_1dd_Smed_v6PMID:28171748
Stückemann et al., 2017		whole organism asexual adult RNA-sequencing evidence
photoreceptor neuronSMED30027710h1SMcG0004292 SMED30027710smed_20140614PMID:22884275
Lapan et al., 2012		whole organism asexual adult colorimetric in situ hybridization evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Ras-related protein Rab-3 vs. Ensembl Human
Match: RAB3C (RAB3C, member RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:30269])

HSP 1 Score: 348.977 bits (894), Expect = 1.586e-120
Identity = 170/221 (76.92%), Postives = 185/221 (83.71%), Query Frame = 2 
Query:  221 MGSTKDA------GSDQNFDYMFKILIIGNSSVGKTSFLFRYADDSFTSAFVSTVGIDFKVKTVYKDDKRIKLQIWDTAGQERYRTITTAYYRGAMGFILMYDIANEESFNAVQDWVTQIKTYSWDNAQVVLVGNKCDLEGDRIISTERGCHLANQLGLEFLETSAKENINVKTVFERLVDIICDKMSESLEADHSVGKSSNSGTRLTSEPQKVLTDQCQC 865
            M S +DA       SDQNFDYMFK+LIIGNSSVGKTSFLFRYADDSFTSAFVSTVGIDFKVKTV+K++KRIKLQIWDTAGQERYRTITTAYYRGAMGFILMYDI NEESFNAVQDW TQIKTYSWDNAQV+LVGNKCD+E +R+ISTERG HL  QLG EF ETSAK+NINVK  FERLVDIICDKMSESLE D ++  ++   TRL   P     + C C
Sbjct:    9 MASAQDARYGQKDSSDQNFDYMFKLLIIGNSSVGKTSFLFRYADDSFTSAFVSTVGIDFKVKTVFKNEKRIKLQIWDTAGQERYRTITTAYYRGAMGFILMYDITNEESFNAVQDWSTQIKTYSWDNAQVILVGNKCDMEDERVISTERGQHLGEQLGFEFFETSAKDNINVKQTFERLVDIICDKMSESLETDPAI-TAAKQNTRLKETPPPPQPN-CAC 227
[Close]
BLAST of Ras-related protein Rab-3 vs. Ensembl Human
Match: RAB3B (RAB3B, member RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:9778])

HSP 1 Score: 331.643 bits (849), Expect = 7.849e-114
Identity = 161/211 (76.30%), Postives = 181/211 (85.78%), Query Frame = 2 
Query:  233 KDAGSDQNFDYMFKILIIGNSSVGKTSFLFRYADDSFTSAFVSTVGIDFKVKTVYKDDKRIKLQIWDTAGQERYRTITTAYYRGAMGFILMYDIANEESFNAVQDWVTQIKTYSWDNAQVVLVGNKCDLEGDRIISTERGCHLANQLGLEFLETSAKENINVKTVFERLVDIICDKMSESLEADHSVGKSSNSGTRLTSEPQKVLTDQCQC 865
            KDA SDQNFDYMFK+LIIGNSSVGKTSFLFRYADD+FT AFVSTVGIDFKVKTVY+ +KR+KLQIWDTAGQERYRTITTAYYRGAMGFILMYDI NEESFNAVQDW TQIKTYSWDNAQV+LVGNKCD+E +R++ TE+G  LA QLG +F E SAKENI+V+  FERLVD ICDKMS+SL+ D S+  SS + TRL+  P  +L   C C
Sbjct:   12 KDA-SDQNFDYMFKLLIIGNSSVGKTSFLFRYADDTFTPAFVSTVGIDFKVKTVYRHEKRVKLQIWDTAGQERYRTITTAYYRGAMGFILMYDITNEESFNAVQDWATQIKTYSWDNAQVILVGNKCDMEEERVVPTEKGQLLAEQLGFDFFEASAKENISVRQAFERLVDAICDKMSDSLDTDPSMLGSSKN-TRLSDTP-PLLQQNCSC 219
[Close]
BLAST of Ras-related protein Rab-3 vs. Ensembl Human
Match: RAB3A (RAB3A, member RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:9777])

HSP 1 Score: 331.257 bits (848), Expect = 1.178e-113
Identity = 159/208 (76.44%), Postives = 177/208 (85.10%), Query Frame = 2 
Query:  245 SDQNFDYMFKILIIGNSSVGKTSFLFRYADDSFTSAFVSTVGIDFKVKTVYKDDKRIKLQIWDTAGQERYRTITTAYYRGAMGFILMYDIANEESFNAVQDWVTQIKTYSWDNAQVVLVGNKCDLEGDRIISTERGCHLANQLGLEFLETSAKENINVKTVFERLVDIICDKMSESLEADHSVGKSSNSGTRLTSEPQKVLTDQ-CQC 865
            SDQNFDYMFKILIIGNSSVGKTSFLFRYADDSFT AFVSTVGIDFKVKT+Y++DKRIKLQIWDTAGQERYRTITTAYYRGAMGFILMYDI NEESFNAVQDW TQIKTYSWDNAQV+LVGNKCD+E +R++S+ERG  LA+ LG EF E SAK+NINVK  FERLVD+IC+KMSESL+        +  G +L+   Q+V   Q C C
Sbjct:   15 SDQNFDYMFKILIIGNSSVGKTSFLFRYADDSFTPAFVSTVGIDFKVKTIYRNDKRIKLQIWDTAGQERYRTITTAYYRGAMGFILMYDITNEESFNAVQDWSTQIKTYSWDNAQVLLVGNKCDMEDERVVSSERGRQLADHLGFEFFEASAKDNINVKQTFERLVDVICEKMSESLDTADPAVTGAKQGPQLSD--QQVPPHQDCAC 220
[Close]
BLAST of Ras-related protein Rab-3 vs. Ensembl Human
Match: RAB3D (RAB3D, member RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:9779])

HSP 1 Score: 322.783 bits (826), Expect = 1.885e-110
Identity = 152/188 (80.85%), Postives = 167/188 (88.83%), Query Frame = 2 
Query:  218 TMGSTKDAGSDQNFDYMFKILIIGNSSVGKTSFLFRYADDSFTSAFVSTVGIDFKVKTVYKDDKRIKLQIWDTAGQERYRTITTAYYRGAMGFILMYDIANEESFNAVQDWVTQIKTYSWDNAQVVLVGNKCDLEGDRIISTERGCHLANQLGLEFLETSAKENINVKTVFERLVDIICDKMSESLEA 781
            T    +DA +DQNFDYMFK+L+IGNSSVGKTSFLFRYADDSFT AFVSTVGIDFKVKTVY+ DKRIKLQIWDTAGQERYRTITTAYYRGAMGF+LMYDIAN+ESF AVQDW TQIKTYSWDNAQV+LVGNKCDLE +R++  E G  LA+ LG EF E SAKENINVK VFERLVD+IC+KM+ESLE 
Sbjct:    7 TQAGPRDA-ADQNFDYMFKLLLIGNSSVGKTSFLFRYADDSFTPAFVSTVGIDFKVKTVYRHDKRIKLQIWDTAGQERYRTITTAYYRGAMGFLLMYDIANQESFAAVQDWATQIKTYSWDNAQVILVGNKCDLEDERVVPAEDGRRLADDLGFEFFEASAKENINVKQVFERLVDVICEKMNESLEP 193
[Close]
BLAST of Ras-related protein Rab-3 vs. Ensembl Human
Match: RAB3D (RAB3D, member RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:9779])

HSP 1 Score: 322.783 bits (826), Expect = 1.885e-110
Identity = 152/188 (80.85%), Postives = 167/188 (88.83%), Query Frame = 2 
Query:  218 TMGSTKDAGSDQNFDYMFKILIIGNSSVGKTSFLFRYADDSFTSAFVSTVGIDFKVKTVYKDDKRIKLQIWDTAGQERYRTITTAYYRGAMGFILMYDIANEESFNAVQDWVTQIKTYSWDNAQVVLVGNKCDLEGDRIISTERGCHLANQLGLEFLETSAKENINVKTVFERLVDIICDKMSESLEA 781
            T    +DA +DQNFDYMFK+L+IGNSSVGKTSFLFRYADDSFT AFVSTVGIDFKVKTVY+ DKRIKLQIWDTAGQERYRTITTAYYRGAMGF+LMYDIAN+ESF AVQDW TQIKTYSWDNAQV+LVGNKCDLE +R++  E G  LA+ LG EF E SAKENINVK VFERLVD+IC+KM+ESLE 
Sbjct:    7 TQAGPRDA-ADQNFDYMFKLLLIGNSSVGKTSFLFRYADDSFTPAFVSTVGIDFKVKTVYRHDKRIKLQIWDTAGQERYRTITTAYYRGAMGFLLMYDIANQESFAAVQDWATQIKTYSWDNAQVILVGNKCDLEDERVVPAEDGRRLADDLGFEFFEASAKENINVKQVFERLVDVICEKMNESLEP 193
[Close]
BLAST of Ras-related protein Rab-3 vs. Ensembl Celegans
Match: rab-3 (Ras-related protein Rab-3 [Source:UniProtKB/Swiss-Prot;Acc:Q94986])

HSP 1 Score: 335.495 bits (859), Expect = 1.436e-115
Identity = 159/208 (76.44%), Postives = 179/208 (86.06%), Query Frame = 2 
Query:  245 SDQNFDYMFKILIIGNSSVGKTSFLFRYADDSFTSAFVSTVGIDFKVKTVYKDDKRIKLQIWDTAGQERYRTITTAYYRGAMGFILMYDIANEESFNAVQDWVTQIKTYSWDNAQVVLVGNKCDLEGDRIISTERGCHLANQLGLEFLETSAKENINVKTVFERLVDIICDKMSESLEADHSVGKSSNSGTRLTSEP-QKVLTDQCQC 865
             DQNFDYMFK+LIIGNSSVGKTSFLFRY DDSFTSAFVSTVGIDFKVKTV++ DKR+KLQIWDTAGQERYRTITTAYYRGAMGFILMYDI NEESFN+VQDW TQIKTYSW+NAQVVLVGNKCD++ +R++S +RG  LA+QLGLEF ETSAKENINVK VFE+LV+IICDKM+ESL+ D    +    G +L + P QK    QC C
Sbjct:   29 PDQNFDYMFKLLIIGNSSVGKTSFLFRYCDDSFTSAFVSTVGIDFKVKTVFRGDKRVKLQIWDTAGQERYRTITTAYYRGAMGFILMYDITNEESFNSVQDWCTQIKTYSWENAQVVLVGNKCDMDSERVVSMDRGRQLADQLGLEFFETSAKENINVKAVFEKLVEIICDKMAESLDKDP---QQQPKGQKLEANPTQKPAQQQCNC 233
[Close]
BLAST of Ras-related protein Rab-3 vs. Ensembl Celegans
Match: rab-3 (Ras-related protein Rab-3 [Source:UniProtKB/Swiss-Prot;Acc:Q94986])

HSP 1 Score: 333.954 bits (855), Expect = 3.601e-115
Identity = 159/208 (76.44%), Postives = 179/208 (86.06%), Query Frame = 2 
Query:  245 SDQNFDYMFKILIIGNSSVGKTSFLFRYADDSFTSAFVSTVGIDFKVKTVYKDDKRIKLQIWDTAGQERYRTITTAYYRGAMGFILMYDIANEESFNAVQDWVTQIKTYSWDNAQVVLVGNKCDLEGDRIISTERGCHLANQLGLEFLETSAKENINVKTVFERLVDIICDKMSESLEADHSVGKSSNSGTRLTSEP-QKVLTDQCQC 865
             DQNFDYMFK+LIIGNSSVGKTSFLFRY DDSFTSAFVSTVGIDFKVKTV++ DKR+KLQIWDTAGQERYRTITTAYYRGAMGFILMYDI NEESFN+VQDW TQIKTYSW+NAQVVLVGNKCD++ +R++S +RG  LA+QLGLEF ETSAKENINVK VFE+LV+IICDKM+ESL+ D    +    G +L + P QK    QC C
Sbjct:   15 PDQNFDYMFKLLIIGNSSVGKTSFLFRYCDDSFTSAFVSTVGIDFKVKTVFRGDKRVKLQIWDTAGQERYRTITTAYYRGAMGFILMYDITNEESFNSVQDWCTQIKTYSWENAQVVLVGNKCDMDSERVVSMDRGRQLADQLGLEFFETSAKENINVKAVFEKLVEIICDKMAESLDKDP---QQQPKGQKLEANPTQKPAQQQCNC 219
[Close]
BLAST of Ras-related protein Rab-3 vs. Ensembl Celegans
Match: rab-8 (RAB family; Rab8 [Source:UniProtKB/TrEMBL;Acc:G5EFC1])

HSP 1 Score: 207.223 bits (526), Expect = 1.526e-65
Identity = 100/189 (52.91%), Postives = 141/189 (74.60%), Query Frame = 2 
Query:  251 QNFDYMFKILIIGNSSVGKTSFLFRYADDSFTSAFVSTVGIDFKVKTVYKDDKRIKLQIWDTAGQERYRTITTAYYRGAMGFILMYDIANEESFNAVQDWVTQIKTYSWDNAQVVLVGNKCDLEGDRIISTERGCHLANQLGLEFLETSAKENINVKTVFERLVDIICDKMSES-LEADHSVGKSSNSG 814
            + +DY+FK+L+IG+S VGKT  LFR++DDSF ++F+ST+GIDFK++T+  D K+IKLQIWDTAGQER+RTITTAYYRGAMG IL+YDI NE SF  +++W+  I+ ++  + + +++GNKCD+E  R +S +RG  LA + G +FLETSAK N+N+   F  L   I  KM ++ + A  SV   SN+G
Sbjct:    3 KTYDYLFKLLLIGDSGVGKTCVLFRFSDDSFNNSFISTIGIDFKIRTIELDGKKIKLQIWDTAGQERFRTITTAYYRGAMGIILVYDITNERSFENIKNWIRNIEEHAASDVERMIIGNKCDIEERREVSRDRGEQLAIEYGTKFLETSAKANLNIDEAFFTLARDIKSKMEQNEMRAGGSV---SNTG 188
[Close]
BLAST of Ras-related protein Rab-3 vs. Ensembl Celegans
Match: rab-8 (RAB family; Rab8 [Source:UniProtKB/TrEMBL;Acc:G5EFC1])

HSP 1 Score: 207.223 bits (526), Expect = 1.526e-65
Identity = 100/189 (52.91%), Postives = 141/189 (74.60%), Query Frame = 2 
Query:  251 QNFDYMFKILIIGNSSVGKTSFLFRYADDSFTSAFVSTVGIDFKVKTVYKDDKRIKLQIWDTAGQERYRTITTAYYRGAMGFILMYDIANEESFNAVQDWVTQIKTYSWDNAQVVLVGNKCDLEGDRIISTERGCHLANQLGLEFLETSAKENINVKTVFERLVDIICDKMSES-LEADHSVGKSSNSG 814
            + +DY+FK+L+IG+S VGKT  LFR++DDSF ++F+ST+GIDFK++T+  D K+IKLQIWDTAGQER+RTITTAYYRGAMG IL+YDI NE SF  +++W+  I+ ++  + + +++GNKCD+E  R +S +RG  LA + G +FLETSAK N+N+   F  L   I  KM ++ + A  SV   SN+G
Sbjct:    3 KTYDYLFKLLLIGDSGVGKTCVLFRFSDDSFNNSFISTIGIDFKIRTIELDGKKIKLQIWDTAGQERFRTITTAYYRGAMGIILVYDITNERSFENIKNWIRNIEEHAASDVERMIIGNKCDIEERREVSRDRGEQLAIEYGTKFLETSAKANLNIDEAFFTLARDIKSKMEQNEMRAGGSV---SNTG 188
[Close]
BLAST of Ras-related protein Rab-3 vs. Ensembl Celegans
Match: rab-1 (RAB family [Source:UniProtKB/TrEMBL;Acc:Q9UAQ6])

HSP 1 Score: 199.904 bits (507), Expect = 8.582e-63
Identity = 94/200 (47.00%), Postives = 135/200 (67.50%), Query Frame = 2 
Query:  239 AGSDQNFDYMFKILIIGNSSVGKTSFLFRYADDSFTSAFVSTVGIDFKVKTVYKDDKRIKLQIWDTAGQERYRTITTAYYRGAMGFILMYDIANEESFNAVQDWVTQIKTYSWDNAQVVLVGNKCDLEGDRIISTERGCHLANQLGLEFLETSAKENINVKTVFERLVDIICDKMSESLEADHSVGKSSNSGTRLT-SEP 835
            A  +  +DY+FK+L+IG+S VGK+  L R+ADD++T +++ST+G+DFK++T+  D K IKLQIWDTAGQER+RTIT++YYRGA G I++YDI ++E+FN V+ W+ +I  Y+ +N   +LVGNKCDL   R + T+     A QLG+ FLETSAK + NV+  F  +   I  +M          G     G R+T S+P
Sbjct:    2 AAMNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQERFRTITSSYYRGAHGIIVVYDITDQETFNNVKQWLQEIDRYACENVNKLLVGNKCDLTAKRAVETQAAQDYAGQLGIPFLETSAKSSTNVEQAFLTMASEIKSRMGPVQ------GAGGAPGVRITGSQP 195
[Close]
BLAST of Ras-related protein Rab-3 vs. Ensembl Fly
Match: Rab3 (gene:FBgn0005586 transcript:FBtr0473383)

HSP 1 Score: 349.747 bits (896), Expect = 2.198e-121
Identity = 167/211 (79.15%), Postives = 185/211 (87.68%), Query Frame = 2 
Query:  233 KDAGSDQNFDYMFKILIIGNSSVGKTSFLFRYADDSFTSAFVSTVGIDFKVKTVYKDDKRIKLQIWDTAGQERYRTITTAYYRGAMGFILMYDIANEESFNAVQDWVTQIKTYSWDNAQVVLVGNKCDLEGDRIISTERGCHLANQLGLEFLETSAKENINVKTVFERLVDIICDKMSESLEADHSVGKSSNSGTRLTSEPQKVLTDQCQC 865
            KDA +DQNFDYMFK+LIIGNSSVGKTSFLFRYADDSFTSAFVSTVGIDFKVKTV++ DKR+KLQIWDTAGQERYRTITTAYYRGAMGFILMYD+ NE+SFN+VQDWVTQIKTYSWDNAQV+LVGNKCD+E  R+IS ERG  LA+QLG+EF ETSAKEN+NVK VFERLVDIICDKMSESL+AD ++      G RLT +PQ      C C
Sbjct:   11 KDA-ADQNFDYMFKLLIIGNSSVGKTSFLFRYADDSFTSAFVSTVGIDFKVKTVFRHDKRVKLQIWDTAGQERYRTITTAYYRGAMGFILMYDVTNEDSFNSVQDWVTQIKTYSWDNAQVILVGNKCDMEDQRVISFERGRQLADQLGVEFFETSAKENVNVKAVFERLVDIICDKMSESLDADPTLVGGGQKGQRLTDQPQGTPNANCNC 220
[Close]
BLAST of Ras-related protein Rab-3 vs. Ensembl Fly
Match: Rab3 (gene:FBgn0005586 transcript:FBtr0088257)

HSP 1 Score: 349.747 bits (896), Expect = 2.198e-121
Identity = 167/211 (79.15%), Postives = 185/211 (87.68%), Query Frame = 2 
Query:  233 KDAGSDQNFDYMFKILIIGNSSVGKTSFLFRYADDSFTSAFVSTVGIDFKVKTVYKDDKRIKLQIWDTAGQERYRTITTAYYRGAMGFILMYDIANEESFNAVQDWVTQIKTYSWDNAQVVLVGNKCDLEGDRIISTERGCHLANQLGLEFLETSAKENINVKTVFERLVDIICDKMSESLEADHSVGKSSNSGTRLTSEPQKVLTDQCQC 865
            KDA +DQNFDYMFK+LIIGNSSVGKTSFLFRYADDSFTSAFVSTVGIDFKVKTV++ DKR+KLQIWDTAGQERYRTITTAYYRGAMGFILMYD+ NE+SFN+VQDWVTQIKTYSWDNAQV+LVGNKCD+E  R+IS ERG  LA+QLG+EF ETSAKEN+NVK VFERLVDIICDKMSESL+AD ++      G RLT +PQ      C C
Sbjct:   11 KDA-ADQNFDYMFKLLIIGNSSVGKTSFLFRYADDSFTSAFVSTVGIDFKVKTVFRHDKRVKLQIWDTAGQERYRTITTAYYRGAMGFILMYDVTNEDSFNSVQDWVTQIKTYSWDNAQVILVGNKCDMEDQRVISFERGRQLADQLGVEFFETSAKENVNVKAVFERLVDIICDKMSESLDADPTLVGGGQKGQRLTDQPQGTPNANCNC 220
[Close]
BLAST of Ras-related protein Rab-3 vs. Ensembl Fly
Match: Rab8 (gene:FBgn0262518 transcript:FBtr0308833)

HSP 1 Score: 202.986 bits (515), Expect = 6.426e-64
Identity = 92/180 (51.11%), Postives = 136/180 (75.56%), Query Frame = 2 
Query:  251 QNFDYMFKILIIGNSSVGKTSFLFRYADDSFTSAFVSTVGIDFKVKTVYKDDKRIKLQIWDTAGQERYRTITTAYYRGAMGFILMYDIANEESFNAVQDWVTQIKTYSWDNAQVVLVGNKCDLEGDRIISTERGCHLANQLGLEFLETSAKENINVKTVFERLVDIICDKMSESLEADHS 790
            + +DY+FK+L+IG+S VGKT  LFR+++D+F + F+ST+GIDFK++T+  D+K+IKLQIWDTAGQER+RTITTAYYRGAMG +L+YDI  E+SF  +++W+  I+  +  + + +L+GNKC+L   R +S ERG  LA + G++F+ETSAK +INV+  F  L   I  K  + +EA++ 
Sbjct:    3 KTYDYLFKLLLIGDSGVGKTCILFRFSEDAFNTTFISTIGIDFKIRTIELDNKKIKLQIWDTAGQERFRTITTAYYRGAMGIMLVYDITQEKSFENIKNWIRNIEENASADVEKMLLGNKCELTDKRQVSKERGEQLAIEYGIKFMETSAKASINVEEAFLTLASDIKAKTEKRMEANNP 182
[Close]
BLAST of Ras-related protein Rab-3 vs. Ensembl Fly
Match: Rab8 (gene:FBgn0262518 transcript:FBtr0074921)

HSP 1 Score: 202.986 bits (515), Expect = 6.426e-64
Identity = 92/180 (51.11%), Postives = 136/180 (75.56%), Query Frame = 2 
Query:  251 QNFDYMFKILIIGNSSVGKTSFLFRYADDSFTSAFVSTVGIDFKVKTVYKDDKRIKLQIWDTAGQERYRTITTAYYRGAMGFILMYDIANEESFNAVQDWVTQIKTYSWDNAQVVLVGNKCDLEGDRIISTERGCHLANQLGLEFLETSAKENINVKTVFERLVDIICDKMSESLEADHS 790
            + +DY+FK+L+IG+S VGKT  LFR+++D+F + F+ST+GIDFK++T+  D+K+IKLQIWDTAGQER+RTITTAYYRGAMG +L+YDI  E+SF  +++W+  I+  +  + + +L+GNKC+L   R +S ERG  LA + G++F+ETSAK +INV+  F  L   I  K  + +EA++ 
Sbjct:    3 KTYDYLFKLLLIGDSGVGKTCILFRFSEDAFNTTFISTIGIDFKIRTIELDNKKIKLQIWDTAGQERFRTITTAYYRGAMGIMLVYDITQEKSFENIKNWIRNIEENASADVEKMLLGNKCELTDKRQVSKERGEQLAIEYGIKFMETSAKASINVEEAFLTLASDIKAKTEKRMEANNP 182
[Close]
BLAST of Ras-related protein Rab-3 vs. Ensembl Fly
Match: Rab10 (gene:FBgn0015789 transcript:FBtr0077337)

HSP 1 Score: 202.601 bits (514), Expect = 7.650e-64
Identity = 95/185 (51.35%), Postives = 135/185 (72.97%), Query Frame = 2 
Query:  245 SDQNFDYMFKILIIGNSSVGKTSFLFRYADDSFTSAFVSTVGIDFKVKTVYKDDKRIKLQIWDTAGQERYRTITTAYYRGAMGFILMYDIANEESFNAVQDWVTQIKTYSWDNAQVVLVGNKCDLEGDRIISTERGCHLANQLGLEFLETSAKENINVKTVFERLVDIICDKMS--ESLEADHSV 793
            + + +D +FK+L+IG+S VGKT  LFR++DD+FTS F+ST+GIDFK+KTV    K+IKLQIWDTAGQER+ TITT+YYRGAMG +L+YDI NE+SF  +  W+  I  ++ ++ + +++GNKCD+   R+++ ERG  +A + G+ F+ETSAK NIN++  F  L + I DK S  ES E    V
Sbjct:    2 AKKTYDLLFKLLLIGDSGVGKTCILFRFSDDAFTSTFISTIGIDFKIKTVELRGKKIKLQIWDTAGQERFHTITTSYYRGAMGIMLVYDITNEKSFENIVKWLRNIDEHANEDVEKMILGNKCDMTDKRVVNKERGEAIAREHGIRFMETSAKSNINIERAFCELAEAILDKTSGRESAENQERV 186
[Close]
BLAST of Ras-related protein Rab-3 vs. Ensembl Zebrafish
Match: rab3c (RAB3C, member RAS oncogene family [Source:ZFIN;Acc:ZDB-GENE-040718-263])

HSP 1 Score: 338.191 bits (866), Expect = 1.042e-116
Identity = 164/219 (74.89%), Postives = 180/219 (82.19%), Query Frame = 2 
Query:  221 MGSTKD----AGSDQNFDYMFKILIIGNSSVGKTSFLFRYADDSFTSAFVSTVGIDFKVKTVYKDDKRIKLQIWDTAGQERYRTITTAYYRGAMGFILMYDIANEESFNAVQDWVTQIKTYSWDNAQVVLVGNKCDLEGDRIISTERGCHLANQLGLEFLETSAKENINVKTVFERLVDIICDKMSESLEADHSVGKSSNSGTRLTSEPQKVLTDQCQC 865
            M +T+D      SDQNFDYMFK+LIIGNSSVGKTSFLFRYADD+FTSAFVSTVGIDFKVKTVYK+DKRIKLQIWDTAGQERYRTITTAYYRGAMGFILMYDI NEESF AVQDW TQIKTYSWDNAQV+L GNKCD+E +RI+S + G  LA QLG EF ETSAK+NINVK  F+RLVDIICDKMS++LEAD +    + S  RLT  P       C C
Sbjct:    1 MAATQDNKQKENSDQNFDYMFKLLIIGNSSVGKTSFLFRYADDTFTSAFVSTVGIDFKVKTVYKNDKRIKLQIWDTAGQERYRTITTAYYRGAMGFILMYDITNEESFAAVQDWATQIKTYSWDNAQVILAGNKCDMEEERIVSVDSGRLLAEQLGFEFFETSAKDNINVKQTFDRLVDIICDKMSDTLEADPAAAGGTPSA-RLTETPAPPQPSDCSC 218
[Close]
BLAST of Ras-related protein Rab-3 vs. Ensembl Zebrafish
Match: rab3c (RAB3C, member RAS oncogene family [Source:ZFIN;Acc:ZDB-GENE-040718-263])

HSP 1 Score: 338.191 bits (866), Expect = 1.042e-116
Identity = 164/219 (74.89%), Postives = 180/219 (82.19%), Query Frame = 2 
Query:  221 MGSTKD----AGSDQNFDYMFKILIIGNSSVGKTSFLFRYADDSFTSAFVSTVGIDFKVKTVYKDDKRIKLQIWDTAGQERYRTITTAYYRGAMGFILMYDIANEESFNAVQDWVTQIKTYSWDNAQVVLVGNKCDLEGDRIISTERGCHLANQLGLEFLETSAKENINVKTVFERLVDIICDKMSESLEADHSVGKSSNSGTRLTSEPQKVLTDQCQC 865
            M +T+D      SDQNFDYMFK+LIIGNSSVGKTSFLFRYADD+FTSAFVSTVGIDFKVKTVYK+DKRIKLQIWDTAGQERYRTITTAYYRGAMGFILMYDI NEESF AVQDW TQIKTYSWDNAQV+L GNKCD+E +RI+S + G  LA QLG EF ETSAK+NINVK  F+RLVDIICDKMS++LEAD +    + S  RLT  P       C C
Sbjct:    1 MAATQDNKQKENSDQNFDYMFKLLIIGNSSVGKTSFLFRYADDTFTSAFVSTVGIDFKVKTVYKNDKRIKLQIWDTAGQERYRTITTAYYRGAMGFILMYDITNEESFAAVQDWATQIKTYSWDNAQVILAGNKCDMEEERIVSVDSGRLLAEQLGFEFFETSAKDNINVKQTFDRLVDIICDKMSDTLEADPAAAGGTPSA-RLTETPAPPQPSDCSC 218
[Close]
BLAST of Ras-related protein Rab-3 vs. Ensembl Zebrafish
Match: rab3c (RAB3C, member RAS oncogene family [Source:ZFIN;Acc:ZDB-GENE-040718-263])

HSP 1 Score: 338.191 bits (866), Expect = 1.564e-116
Identity = 164/219 (74.89%), Postives = 180/219 (82.19%), Query Frame = 2 
Query:  221 MGSTKD----AGSDQNFDYMFKILIIGNSSVGKTSFLFRYADDSFTSAFVSTVGIDFKVKTVYKDDKRIKLQIWDTAGQERYRTITTAYYRGAMGFILMYDIANEESFNAVQDWVTQIKTYSWDNAQVVLVGNKCDLEGDRIISTERGCHLANQLGLEFLETSAKENINVKTVFERLVDIICDKMSESLEADHSVGKSSNSGTRLTSEPQKVLTDQCQC 865
            M +T+D      SDQNFDYMFK+LIIGNSSVGKTSFLFRYADD+FTSAFVSTVGIDFKVKTVYK+DKRIKLQIWDTAGQERYRTITTAYYRGAMGFILMYDI NEESF AVQDW TQIKTYSWDNAQV+L GNKCD+E +RI+S + G  LA QLG EF ETSAK+NINVK  F+RLVDIICDKMS++LEAD +    + S  RLT  P       C C
Sbjct:    7 MAATQDNKQKENSDQNFDYMFKLLIIGNSSVGKTSFLFRYADDTFTSAFVSTVGIDFKVKTVYKNDKRIKLQIWDTAGQERYRTITTAYYRGAMGFILMYDITNEESFAAVQDWATQIKTYSWDNAQVILAGNKCDMEEERIVSVDSGRLLAEQLGFEFFETSAKDNINVKQTFDRLVDIICDKMSDTLEADPAAAGGTPSA-RLTETPAPPQPSDCSC 224
[Close]
BLAST of Ras-related protein Rab-3 vs. Ensembl Zebrafish
Match: rab3ab (RAB3A, member RAS oncogene family, b [Source:ZFIN;Acc:ZDB-GENE-041210-268])

HSP 1 Score: 332.413 bits (851), Expect = 2.599e-114
Identity = 157/207 (75.85%), Postives = 175/207 (84.54%), Query Frame = 2 
Query:  245 SDQNFDYMFKILIIGNSSVGKTSFLFRYADDSFTSAFVSTVGIDFKVKTVYKDDKRIKLQIWDTAGQERYRTITTAYYRGAMGFILMYDIANEESFNAVQDWVTQIKTYSWDNAQVVLVGNKCDLEGDRIISTERGCHLANQLGLEFLETSAKENINVKTVFERLVDIICDKMSESLEADHSVGKSSNSGTRLTSEPQKVLTDQCQC 865
            SDQNFDYMFKILIIGNSSVGKTSFLFRYADDSFT AFVSTVGIDFKVKT+Y++DKRIKLQIWDTAGQERYRTITTAYYRGAMGFILMYDI NEESF AVQDW TQIKTYSWDNAQV+LVGNKCD+E +R++++ERG  L+  LG E+ E SAK+NINVK  FERLVDIIC+KMSESL+A       +  G +LT +P     D C C
Sbjct:   15 SDQNFDYMFKILIIGNSSVGKTSFLFRYADDSFTPAFVSTVGIDFKVKTIYRNDKRIKLQIWDTAGQERYRTITTAYYRGAMGFILMYDITNEESFAAVQDWSTQIKTYSWDNAQVLLVGNKCDMEDERVVASERGRQLSEHLGFEYFEASAKDNINVKQTFERLVDIICEKMSESLDAADPAVTGAKQGPQLTEQPAAPHQD-CAC 220
[Close]
BLAST of Ras-related protein Rab-3 vs. Ensembl Zebrafish
Match: rab3aa (RAB3A, member RAS oncogene family, a [Source:ZFIN;Acc:ZDB-GENE-040801-2])

HSP 1 Score: 328.561 bits (841), Expect = 6.876e-113
Identity = 156/221 (70.59%), Postives = 181/221 (81.90%), Query Frame = 2 
Query:  221 MGSTKDA------GSDQNFDYMFKILIIGNSSVGKTSFLFRYADDSFTSAFVSTVGIDFKVKTVYKDDKRIKLQIWDTAGQERYRTITTAYYRGAMGFILMYDIANEESFNAVQDWVTQIKTYSWDNAQVVLVGNKCDLEGDRIISTERGCHLANQLGLEFLETSAKENINVKTVFERLVDIICDKMSESLEADHSVGKSSNSGTRLTSEPQKVLTDQCQC 865
            M S  DA       ++QNFDYMFK+LIIGNSSVGKTSFLFRYADDSFT AFVSTVGIDFKVKT+Y++DKRIKLQIWDTAGQERYRTITTAYYRGAMGFILMYDI NE+SFNAVQDW TQIKTYSWDNAQV+LVGNKCD+E +R+++ +RG  L+ QLG EF E SAK+NINVK  FERLVD+IC++MSE+LE+       +  G  L+ +PQ+   D C C
Sbjct:    1 MASANDARYGQKDSAEQNFDYMFKVLIIGNSSVGKTSFLFRYADDSFTPAFVSTVGIDFKVKTIYRNDKRIKLQIWDTAGQERYRTITTAYYRGAMGFILMYDITNEDSFNAVQDWSTQIKTYSWDNAQVLLVGNKCDMEDERVVAGQRGRQLSEQLGFEFFEASAKDNINVKQTFERLVDVICERMSENLESADPSMTGNKLGPELSEQPQRSHKD-CAC 220
[Close]
BLAST of Ras-related protein Rab-3 vs. Ensembl Xenopus
Match: rab3a (RAB3A, member RAS oncogene family [Source:NCBI gene;Acc:549180])

HSP 1 Score: 332.798 bits (852), Expect = 2.367e-114
Identity = 159/207 (76.81%), Postives = 174/207 (84.06%), Query Frame = 2 
Query:  245 SDQNFDYMFKILIIGNSSVGKTSFLFRYADDSFTSAFVSTVGIDFKVKTVYKDDKRIKLQIWDTAGQERYRTITTAYYRGAMGFILMYDIANEESFNAVQDWVTQIKTYSWDNAQVVLVGNKCDLEGDRIISTERGCHLANQLGLEFLETSAKENINVKTVFERLVDIICDKMSESLEADHSVGKSSNSGTRLTSEPQKVLTDQCQC 865
            SDQNFDYMFKILIIGNSSVGKTSFLFRYADDSFT AFVSTVGIDFKVKT+Y++DKRIKLQIWDTAGQERYRTITTAYYRGAMGFILMYDI NEESFNAVQDW TQIKTYSWDNAQV+LVGNKCD+E +R++S+ERG  LA  LG EF E SAK+NINVK  FERLVDIIC+KMSESL+        +  G +LT +      D C C
Sbjct:   15 SDQNFDYMFKILIIGNSSVGKTSFLFRYADDSFTPAFVSTVGIDFKVKTIYRNDKRIKLQIWDTAGQERYRTITTAYYRGAMGFILMYDITNEESFNAVQDWSTQIKTYSWDNAQVLLVGNKCDMEDERVVSSERGRQLAEHLGFEFFEASAKDNINVKQTFERLVDIICEKMSESLDTADPAVTGAKQGPQLTDQQAPPHQD-CAC 220
[Close]
BLAST of Ras-related protein Rab-3 vs. Ensembl Xenopus
Match: rab3b (RAB3B, member RAS oncogene family [Source:NCBI gene;Acc:100101786])

HSP 1 Score: 332.028 bits (850), Expect = 4.834e-114
Identity = 159/207 (76.81%), Postives = 178/207 (85.99%), Query Frame = 2 
Query:  245 SDQNFDYMFKILIIGNSSVGKTSFLFRYADDSFTSAFVSTVGIDFKVKTVYKDDKRIKLQIWDTAGQERYRTITTAYYRGAMGFILMYDIANEESFNAVQDWVTQIKTYSWDNAQVVLVGNKCDLEGDRIISTERGCHLANQLGLEFLETSAKENINVKTVFERLVDIICDKMSESLEADHSVGKSSNSGTRLTSEPQKVLTDQCQC 865
            SDQNFDYMFK+LIIGNSSVGKTSFLFRYADD+FTSAFVSTVGIDFKVKTVY++DKR+KLQIWDTAGQERYRTITTAYYRGAMGFILMYDI +E S+NAVQDW TQIKTYSWDNAQV+LVGNKCD+E +R+I+ E+G HLA+QLG EF E SAKENI VK VFERLVDIICDKMSESL+ D   G  +   T  T+ P   +  +C C
Sbjct:   15 SDQNFDYMFKLLIIGNSSVGKTSFLFRYADDTFTSAFVSTVGIDFKVKTVYRNDKRVKLQIWDTAGQERYRTITTAYYRGAMGFILMYDITSESSYNAVQDWATQIKTYSWDNAQVILVGNKCDMEEERVIAPEKGKHLADQLGFEFFEASAKENIQVKQVFERLVDIICDKMSESLDTDQPPGGKNLRFTD-TAPP---IHQKCSC 217
[Close]
BLAST of Ras-related protein Rab-3 vs. Ensembl Xenopus
Match: RAB3C (RAB3C, member RAS oncogene family [Source:NCBI gene;Acc:100496123])

HSP 1 Score: 331.257 bits (848), Expect = 1.084e-113
Identity = 156/178 (87.64%), Postives = 167/178 (93.82%), Query Frame = 2 
Query:  245 SDQNFDYMFKILIIGNSSVGKTSFLFRYADDSFTSAFVSTVGIDFKVKTVYKDDKRIKLQIWDTAGQERYRTITTAYYRGAMGFILMYDIANEESFNAVQDWVTQIKTYSWDNAQVVLVGNKCDLEGDRIISTERGCHLANQLGLEFLETSAKENINVKTVFERLVDIICDKMSESLE 778
            SDQNFDYMFK+LIIGNSSVGKTSFLFRYADDSFTSAFVSTVGIDFKVKTV+K++KRIKLQIWDTAGQERYRTITTAYYRGAMGFILMYDI NEESFNAVQDW TQIKTYSWDNAQV+LVGNKCD+E +R+IS ERG HLA QLG EF E SAK+NINVK  FERLVDIICDKMSE++E
Sbjct:   23 SDQNFDYMFKLLIIGNSSVGKTSFLFRYADDSFTSAFVSTVGIDFKVKTVFKNEKRIKLQIWDTAGQERYRTITTAYYRGAMGFILMYDITNEESFNAVQDWSTQIKTYSWDNAQVILVGNKCDMEDERVISAERGKHLAEQLGFEFFEASAKDNINVKQTFERLVDIICDKMSENIE 200
[Close]
BLAST of Ras-related protein Rab-3 vs. Ensembl Xenopus
Match: RAB3C (RAB3C, member RAS oncogene family [Source:NCBI gene;Acc:100496123])

HSP 1 Score: 330.487 bits (846), Expect = 1.943e-113
Identity = 156/178 (87.64%), Postives = 167/178 (93.82%), Query Frame = 2 
Query:  245 SDQNFDYMFKILIIGNSSVGKTSFLFRYADDSFTSAFVSTVGIDFKVKTVYKDDKRIKLQIWDTAGQERYRTITTAYYRGAMGFILMYDIANEESFNAVQDWVTQIKTYSWDNAQVVLVGNKCDLEGDRIISTERGCHLANQLGLEFLETSAKENINVKTVFERLVDIICDKMSESLE 778
            SDQNFDYMFK+LIIGNSSVGKTSFLFRYADDSFTSAFVSTVGIDFKVKTV+K++KRIKLQIWDTAGQERYRTITTAYYRGAMGFILMYDI NEESFNAVQDW TQIKTYSWDNAQV+LVGNKCD+E +R+IS ERG HLA QLG EF E SAK+NINVK  FERLVDIICDKMSE++E
Sbjct:   15 SDQNFDYMFKLLIIGNSSVGKTSFLFRYADDSFTSAFVSTVGIDFKVKTVFKNEKRIKLQIWDTAGQERYRTITTAYYRGAMGFILMYDITNEESFNAVQDWSTQIKTYSWDNAQVILVGNKCDMEDERVISAERGKHLAEQLGFEFFEASAKDNINVKQTFERLVDIICDKMSENIE 192
[Close]
BLAST of Ras-related protein Rab-3 vs. Ensembl Xenopus
Match: tekt1 (tektin 1 [Source:Xenbase;Acc:XB-GENE-5929242])

HSP 1 Score: 323.553 bits (828), Expect = 7.655e-111
Identity = 161/216 (74.54%), Postives = 176/216 (81.48%), Query Frame = 2 
Query:  218 TMGSTKDAGSDQNFDYMFKILIIGNSSVGKTSFLFRYADDSFTSAFVSTVGIDFKVKTVYKDDKRIKLQIWDTAGQERYRTITTAYYRGAMGFILMYDIANEESFNAVQDWVTQIKTYSWDNAQVVLVGNKCDLEGDRIISTERGCHLANQLGLEFLETSAKENINVKTVFERLVDIICDKMSESLEADHSVGKSSNSGTRLTSEPQKVLTDQCQC 865
            T    KDA +DQ+FDYMFK+LIIGNSSVGKTSFLFRYADDSFTSAFVSTVGIDFKVKTVY+++KR+KLQIWDTAGQERYRTITTAYYRGAMGF+LMYDI+N ESFNAVQDW TQIKTYSWDNAQV+LVGNKCDLE DR+I  E G  LA +LG EF E SAK+NINVK VFERLVDIIC+KM+ESLE          SGT   SE        C C
Sbjct:    7 TRQPQKDA-ADQSFDYMFKLLIIGNSSVGKTSFLFRYADDSFTSAFVSTVGIDFKVKTVYRNEKRVKLQIWDTAGQERYRTITTAYYRGAMGFLLMYDISNLESFNAVQDWATQIKTYSWDNAQVLLVGNKCDLEDDRVIPAEDGRKLAEELGFEFFEASAKDNINVKQVFERLVDIICEKMNESLE-----NGPVPSGTAQLSESAPKEHSNCSC 216
[Close]
BLAST of Ras-related protein Rab-3 vs. Ensembl Mouse
Match: Rab3c (RAB3C, member RAS oncogene family [Source:MGI Symbol;Acc:MGI:1914545])

HSP 1 Score: 343.584 bits (880), Expect = 1.361e-118
Identity = 168/221 (76.02%), Postives = 183/221 (82.81%), Query Frame = 2 
Query:  221 MGSTKDA------GSDQNFDYMFKILIIGNSSVGKTSFLFRYADDSFTSAFVSTVGIDFKVKTVYKDDKRIKLQIWDTAGQERYRTITTAYYRGAMGFILMYDIANEESFNAVQDWVTQIKTYSWDNAQVVLVGNKCDLEGDRIISTERGCHLANQLGLEFLETSAKENINVKTVFERLVDIICDKMSESLEADHSVGKSSNSGTRLTSEPQKVLTDQCQC 865
            M S +DA       SDQNFDYMFK+LIIGNSSVGKTSFLFRYADDSFTSAFVSTVGIDFKVKTV+K++KRIKLQIWDTAGQERYRTITTAYYRGAMGFILMYDI NEESFNAVQDW TQIKTYSWDNAQV+L GNKCD+E +R++STERG  L  QLG EF ETSAK+NINVK  FERLVDIICDKMSESLE D ++  +  S TRL   P     + C C
Sbjct:    9 MASAQDARFGQKDSSDQNFDYMFKLLIIGNSSVGKTSFLFRYADDSFTSAFVSTVGIDFKVKTVFKNEKRIKLQIWDTAGQERYRTITTAYYRGAMGFILMYDITNEESFNAVQDWSTQIKTYSWDNAQVILAGNKCDMEDERVVSTERGQRLGEQLGFEFFETSAKDNINVKQTFERLVDIICDKMSESLETDPAITAAKQS-TRLKETPPPPQPN-CGC 227
[Close]
BLAST of Ras-related protein Rab-3 vs. Ensembl Mouse
Match: Rab3c (RAB3C, member RAS oncogene family [Source:MGI Symbol;Acc:MGI:1914545])

HSP 1 Score: 342.428 bits (877), Expect = 2.974e-118
Identity = 168/221 (76.02%), Postives = 183/221 (82.81%), Query Frame = 2 
Query:  221 MGSTKDA------GSDQNFDYMFKILIIGNSSVGKTSFLFRYADDSFTSAFVSTVGIDFKVKTVYKDDKRIKLQIWDTAGQERYRTITTAYYRGAMGFILMYDIANEESFNAVQDWVTQIKTYSWDNAQVVLVGNKCDLEGDRIISTERGCHLANQLGLEFLETSAKENINVKTVFERLVDIICDKMSESLEADHSVGKSSNSGTRLTSEPQKVLTDQCQC 865
            M S +DA       SDQNFDYMFK+LIIGNSSVGKTSFLFRYADDSFTSAFVSTVGIDFKVKTV+K++KRIKLQIWDTAGQERYRTITTAYYRGAMGFILMYDI NEESFNAVQDW TQIKTYSWDNAQV+L GNKCD+E +R++STERG  L  QLG EF ETSAK+NINVK  FERLVDIICDKMSESLE D ++  +  S TRL   P     + C C
Sbjct:    7 MASAQDARFGQKDSSDQNFDYMFKLLIIGNSSVGKTSFLFRYADDSFTSAFVSTVGIDFKVKTVFKNEKRIKLQIWDTAGQERYRTITTAYYRGAMGFILMYDITNEESFNAVQDWSTQIKTYSWDNAQVILAGNKCDMEDERVVSTERGQRLGEQLGFEFFETSAKDNINVKQTFERLVDIICDKMSESLETDPAITAAKQS-TRLKETPPPPQPN-CGC 225
[Close]
BLAST of Ras-related protein Rab-3 vs. Ensembl Mouse
Match: Rab3d (RAB3D, member RAS oncogene family [Source:MGI Symbol;Acc:MGI:97844])

HSP 1 Score: 334.339 bits (856), Expect = 4.720e-115
Identity = 164/216 (75.93%), Postives = 178/216 (82.41%), Query Frame = 2 
Query:  224 GSTKDAGSDQNFDYMFKILIIGNSSVGKTSFLFRYADDSFTSAFVSTVGIDFKVKTVYKDDKRIKLQIWDTAGQERYRTITTAYYRGAMGFILMYDIANEESFNAVQDWVTQIKTYSWDNAQVVLVGNKCDLEGDRIISTERGCHLANQLGLEFLETSAKENINVKTVFERLVDIICDKMSESLEADHSVGKSSNSGTRL--TSEPQKVLTDQCQC 865
             S +DA +DQNFDYMFK+L+IGNSSVGKTSFLFRYADDSFT AFVSTVGIDFKVKTVY+ DKRIKLQIWDTAGQERYRTITTAYYRGAMGF+LMYDIAN+ESF AVQDW TQIKTYSWDNAQV+LVGNKCDLE +R++  E G  LA+ LG EF E SAKENINVK VFERLVDIICDKM+ESLE   S G S+  G  L  T  PQ      C C
Sbjct:    9 ASPRDA-ADQNFDYMFKLLLIGNSSVGKTSFLFRYADDSFTPAFVSTVGIDFKVKTVYRHDKRIKLQIWDTAGQERYRTITTAYYRGAMGFLLMYDIANQESFTAVQDWATQIKTYSWDNAQVILVGNKCDLEDERVVPAEDGRRLADDLGFEFFEASAKENINVKQVFERLVDIICDKMNESLEPSSSPG-SNGKGPALGDTPPPQP---SSCSC 219
[Close]
BLAST of Ras-related protein Rab-3 vs. Ensembl Mouse
Match: Rab3d (RAB3D, member RAS oncogene family [Source:MGI Symbol;Acc:MGI:97844])

HSP 1 Score: 334.339 bits (856), Expect = 4.720e-115
Identity = 164/216 (75.93%), Postives = 178/216 (82.41%), Query Frame = 2 
Query:  224 GSTKDAGSDQNFDYMFKILIIGNSSVGKTSFLFRYADDSFTSAFVSTVGIDFKVKTVYKDDKRIKLQIWDTAGQERYRTITTAYYRGAMGFILMYDIANEESFNAVQDWVTQIKTYSWDNAQVVLVGNKCDLEGDRIISTERGCHLANQLGLEFLETSAKENINVKTVFERLVDIICDKMSESLEADHSVGKSSNSGTRL--TSEPQKVLTDQCQC 865
             S +DA +DQNFDYMFK+L+IGNSSVGKTSFLFRYADDSFT AFVSTVGIDFKVKTVY+ DKRIKLQIWDTAGQERYRTITTAYYRGAMGF+LMYDIAN+ESF AVQDW TQIKTYSWDNAQV+LVGNKCDLE +R++  E G  LA+ LG EF E SAKENINVK VFERLVDIICDKM+ESLE   S G S+  G  L  T  PQ      C C
Sbjct:    9 ASPRDA-ADQNFDYMFKLLLIGNSSVGKTSFLFRYADDSFTPAFVSTVGIDFKVKTVYRHDKRIKLQIWDTAGQERYRTITTAYYRGAMGFLLMYDIANQESFTAVQDWATQIKTYSWDNAQVILVGNKCDLEDERVVPAEDGRRLADDLGFEFFEASAKENINVKQVFERLVDIICDKMNESLEPSSSPG-SNGKGPALGDTPPPQP---SSCSC 219
[Close]
BLAST of Ras-related protein Rab-3 vs. Ensembl Mouse
Match: Rab3a (Ras-related protein Rab-3A [Source:UniProtKB/Swiss-Prot;Acc:P63011])

HSP 1 Score: 332.413 bits (851), Expect = 2.111e-114
Identity = 158/207 (76.33%), Postives = 175/207 (84.54%), Query Frame = 2 
Query:  245 SDQNFDYMFKILIIGNSSVGKTSFLFRYADDSFTSAFVSTVGIDFKVKTVYKDDKRIKLQIWDTAGQERYRTITTAYYRGAMGFILMYDIANEESFNAVQDWVTQIKTYSWDNAQVVLVGNKCDLEGDRIISTERGCHLANQLGLEFLETSAKENINVKTVFERLVDIICDKMSESLEADHSVGKSSNSGTRLTSEPQKVLTDQCQC 865
            SDQNFDYMFKILIIGNSSVGKTSFLFRYADDSFT AFVSTVGIDFKVKT+Y++DKRIKLQIWDTAGQERYRTITTAYYRGAMGFILMYDI NEESFNAVQDW TQIKTYSWDNAQV+LVGNKCD+E +R++S+ERG  LA+ LG EF E SAK+NINVK  FERLVD+IC+KMSESL+        +  G +LT +      D C C
Sbjct:   15 SDQNFDYMFKILIIGNSSVGKTSFLFRYADDSFTPAFVSTVGIDFKVKTIYRNDKRIKLQIWDTAGQERYRTITTAYYRGAMGFILMYDITNEESFNAVQDWSTQIKTYSWDNAQVLLVGNKCDMEDERVVSSERGRQLADHLGFEFFEASAKDNINVKQTFERLVDVICEKMSESLDTADPAVTGAKQGPQLTDQQAPPHQD-CAC 220
[Close]
BLAST of Ras-related protein Rab-3 vs. UniProt/SwissProt
Match: sp|P25228|RAB3_DROME (Ras-related protein Rab-3 OS=Drosophila melanogaster OX=7227 GN=Rab3 PE=1 SV=1)

HSP 1 Score: 349.747 bits (896), Expect = 2.203e-120
Identity = 167/211 (79.15%), Postives = 185/211 (87.68%), Query Frame = 2 
Query:  233 KDAGSDQNFDYMFKILIIGNSSVGKTSFLFRYADDSFTSAFVSTVGIDFKVKTVYKDDKRIKLQIWDTAGQERYRTITTAYYRGAMGFILMYDIANEESFNAVQDWVTQIKTYSWDNAQVVLVGNKCDLEGDRIISTERGCHLANQLGLEFLETSAKENINVKTVFERLVDIICDKMSESLEADHSVGKSSNSGTRLTSEPQKVLTDQCQC 865
            KDA +DQNFDYMFK+LIIGNSSVGKTSFLFRYADDSFTSAFVSTVGIDFKVKTV++ DKR+KLQIWDTAGQERYRTITTAYYRGAMGFILMYD+ NE+SFN+VQDWVTQIKTYSWDNAQV+LVGNKCD+E  R+IS ERG  LA+QLG+EF ETSAKEN+NVK VFERLVDIICDKMSESL+AD ++      G RLT +PQ      C C
Sbjct:   11 KDA-ADQNFDYMFKLLIIGNSSVGKTSFLFRYADDSFTSAFVSTVGIDFKVKTVFRHDKRVKLQIWDTAGQERYRTITTAYYRGAMGFILMYDVTNEDSFNSVQDWVTQIKTYSWDNAQVILVGNKCDMEDQRVISFERGRQLADQLGVEFFETSAKENVNVKAVFERLVDIICDKMSESLDADPTLVGGGQKGQRLTDQPQGTPNANCNC 220
[Close]
BLAST of Ras-related protein Rab-3 vs. UniProt/SwissProt
Match: sp|Q96E17|RAB3C_HUMAN (Ras-related protein Rab-3C OS=Homo sapiens OX=9606 GN=RAB3C PE=1 SV=1)

HSP 1 Score: 348.977 bits (894), Expect = 7.616e-120
Identity = 170/221 (76.92%), Postives = 185/221 (83.71%), Query Frame = 2 
Query:  221 MGSTKDA------GSDQNFDYMFKILIIGNSSVGKTSFLFRYADDSFTSAFVSTVGIDFKVKTVYKDDKRIKLQIWDTAGQERYRTITTAYYRGAMGFILMYDIANEESFNAVQDWVTQIKTYSWDNAQVVLVGNKCDLEGDRIISTERGCHLANQLGLEFLETSAKENINVKTVFERLVDIICDKMSESLEADHSVGKSSNSGTRLTSEPQKVLTDQCQC 865
            M S +DA       SDQNFDYMFK+LIIGNSSVGKTSFLFRYADDSFTSAFVSTVGIDFKVKTV+K++KRIKLQIWDTAGQERYRTITTAYYRGAMGFILMYDI NEESFNAVQDW TQIKTYSWDNAQV+LVGNKCD+E +R+ISTERG HL  QLG EF ETSAK+NINVK  FERLVDIICDKMSESLE D ++  ++   TRL   P     + C C
Sbjct:    9 MASAQDARYGQKDSSDQNFDYMFKLLIIGNSSVGKTSFLFRYADDSFTSAFVSTVGIDFKVKTVFKNEKRIKLQIWDTAGQERYRTITTAYYRGAMGFILMYDITNEESFNAVQDWSTQIKTYSWDNAQVILVGNKCDMEDERVISTERGQHLGEQLGFEFFETSAKDNINVKQTFERLVDIICDKMSESLETDPAI-TAAKQNTRLKETPPPPQPN-CAC 227
[Close]
BLAST of Ras-related protein Rab-3 vs. UniProt/SwissProt
Match: sp|P10949|RAB3C_BOVIN (Ras-related protein Rab-3C OS=Bos taurus OX=9913 GN=RAB3C PE=2 SV=3)

HSP 1 Score: 347.821 bits (891), Expect = 1.747e-119
Identity = 170/221 (76.92%), Postives = 185/221 (83.71%), Query Frame = 2 
Query:  221 MGSTKDA------GSDQNFDYMFKILIIGNSSVGKTSFLFRYADDSFTSAFVSTVGIDFKVKTVYKDDKRIKLQIWDTAGQERYRTITTAYYRGAMGFILMYDIANEESFNAVQDWVTQIKTYSWDNAQVVLVGNKCDLEGDRIISTERGCHLANQLGLEFLETSAKENINVKTVFERLVDIICDKMSESLEADHSVGKSSNSGTRLTSEPQKVLTDQCQC 865
            M S +DA       SDQNFDYMFK+LIIGNSSVGKTSFLFRYADDSFTSAFVSTVGIDFKVKTV+K++KRIKLQIWDTAGQERYRTITTAYYRGAMGFILMYDI NEESFNAVQDW TQIKTYSWDNAQV+LVGNKCD+E +R+ISTERG HL  QLG EF ETSAK+NINVK  FERLVDIICDKMSESLE D ++  ++   TRL   P     + C C
Sbjct:    9 MASAQDARYGQKDSSDQNFDYMFKLLIIGNSSVGKTSFLFRYADDSFTSAFVSTVGIDFKVKTVFKNEKRIKLQIWDTAGQERYRTITTAYYRGAMGFILMYDITNEESFNAVQDWSTQIKTYSWDNAQVILVGNKCDMEDERVISTERGQHLGEQLGFEFFETSAKDNINVKQTFERLVDIICDKMSESLETDPAI-TAAKQNTRLKETPPPPQPN-CGC 227
[Close]
BLAST of Ras-related protein Rab-3 vs. UniProt/SwissProt
Match: sp|P62824|RAB3C_RAT (Ras-related protein Rab-3C OS=Rattus norvegicus OX=10116 GN=Rab3c PE=1 SV=1)

HSP 1 Score: 343.584 bits (880), Expect = 9.520e-118
Identity = 168/221 (76.02%), Postives = 183/221 (82.81%), Query Frame = 2 
Query:  221 MGSTKDA------GSDQNFDYMFKILIIGNSSVGKTSFLFRYADDSFTSAFVSTVGIDFKVKTVYKDDKRIKLQIWDTAGQERYRTITTAYYRGAMGFILMYDIANEESFNAVQDWVTQIKTYSWDNAQVVLVGNKCDLEGDRIISTERGCHLANQLGLEFLETSAKENINVKTVFERLVDIICDKMSESLEADHSVGKSSNSGTRLTSEPQKVLTDQCQC 865
            M S +DA       SDQNFDYMFK+LIIGNSSVGKTSFLFRYADDSFTSAFVSTVGIDFKVKTV+K++KRIKLQIWDTAGQERYRTITTAYYRGAMGFILMYDI NEESFNAVQDW TQIKTYSWDNAQV+L GNKCD+E +R++STERG  L  QLG EF ETSAK+NINVK  FERLVDIICDKMSESLE D ++  +  S TRL   P     + C C
Sbjct:    9 MASAQDARFGQKDSSDQNFDYMFKLLIIGNSSVGKTSFLFRYADDSFTSAFVSTVGIDFKVKTVFKNEKRIKLQIWDTAGQERYRTITTAYYRGAMGFILMYDITNEESFNAVQDWSTQIKTYSWDNAQVILAGNKCDMEDERVVSTERGQRLGEQLGFEFFETSAKDNINVKQTFERLVDIICDKMSESLETDPAITAAKQS-TRLKETPPPPQPN-CGC 227
[Close]
BLAST of Ras-related protein Rab-3 vs. UniProt/SwissProt
Match: sp|P62823|RAB3C_MOUSE (Ras-related protein Rab-3C OS=Mus musculus OX=10090 GN=Rab3c PE=1 SV=1)

HSP 1 Score: 343.584 bits (880), Expect = 9.520e-118
Identity = 168/221 (76.02%), Postives = 183/221 (82.81%), Query Frame = 2 
Query:  221 MGSTKDA------GSDQNFDYMFKILIIGNSSVGKTSFLFRYADDSFTSAFVSTVGIDFKVKTVYKDDKRIKLQIWDTAGQERYRTITTAYYRGAMGFILMYDIANEESFNAVQDWVTQIKTYSWDNAQVVLVGNKCDLEGDRIISTERGCHLANQLGLEFLETSAKENINVKTVFERLVDIICDKMSESLEADHSVGKSSNSGTRLTSEPQKVLTDQCQC 865
            M S +DA       SDQNFDYMFK+LIIGNSSVGKTSFLFRYADDSFTSAFVSTVGIDFKVKTV+K++KRIKLQIWDTAGQERYRTITTAYYRGAMGFILMYDI NEESFNAVQDW TQIKTYSWDNAQV+L GNKCD+E +R++STERG  L  QLG EF ETSAK+NINVK  FERLVDIICDKMSESLE D ++  +  S TRL   P     + C C
Sbjct:    9 MASAQDARFGQKDSSDQNFDYMFKLLIIGNSSVGKTSFLFRYADDSFTSAFVSTVGIDFKVKTVFKNEKRIKLQIWDTAGQERYRTITTAYYRGAMGFILMYDITNEESFNAVQDWSTQIKTYSWDNAQVILAGNKCDMEDERVVSTERGQRLGEQLGFEFFETSAKDNINVKQTFERLVDIICDKMSESLETDPAITAAKQS-TRLKETPPPPQPN-CGC 227
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BLAST of Ras-related protein Rab-3 vs. TrEMBL
Match: A0A1S3H6N1 (ras-related protein Rab-3 isoform X5 OS=Lingula unguis OX=7574 GN=LOC106152563 PE=4 SV=1)

HSP 1 Score: 358.607 bits (919), Expect = 2.621e-121
Identity = 172/211 (81.52%), Postives = 191/211 (90.52%), Query Frame = 2 
Query:  233 KDAGSDQNFDYMFKILIIGNSSVGKTSFLFRYADDSFTSAFVSTVGIDFKVKTVYKDDKRIKLQIWDTAGQERYRTITTAYYRGAMGFILMYDIANEESFNAVQDWVTQIKTYSWDNAQVVLVGNKCDLEGDRIISTERGCHLANQLGLEFLETSAKENINVKTVFERLVDIICDKMSESLEADHSVGKSSNSGTRLTSEPQKVLTDQCQC 865
            KDA +DQNFDYMFK+LIIGNSSVGKTSFLFRYADDSFTSAFVSTVGIDFKVKTV++ DKR+KLQIWDTAGQERYRTITTAYYRGAMGFILMYD+ NEESFNAVQDWVTQIKTYSWDNAQVVLVGNKCDLE +R++STERG  LA+QLGLEF ETSAKENINVK VFERLVDIIC+KMSESL++D ++  +   GTRLT  P +  ++ CQC
Sbjct:   18 KDA-ADQNFDYMFKLLIIGNSSVGKTSFLFRYADDSFTSAFVSTVGIDFKVKTVFRQDKRVKLQIWDTAGQERYRTITTAYYRGAMGFILMYDVTNEESFNAVQDWVTQIKTYSWDNAQVVLVGNKCDLEDERVVSTERGKQLADQLGLEFFETSAKENINVKAVFERLVDIICEKMSESLDSDPTIVSNQRGGTRLTETPNQQASN-CQC 226
[Close]
BLAST of Ras-related protein Rab-3 vs. TrEMBL
Match: A0A1S3H6L2 (ras-related protein Rab-3 isoform X6 OS=Lingula unguis OX=7574 GN=LOC106152563 PE=4 SV=1)

HSP 1 Score: 358.221 bits (918), Expect = 2.937e-121
Identity = 172/211 (81.52%), Postives = 191/211 (90.52%), Query Frame = 2 
Query:  233 KDAGSDQNFDYMFKILIIGNSSVGKTSFLFRYADDSFTSAFVSTVGIDFKVKTVYKDDKRIKLQIWDTAGQERYRTITTAYYRGAMGFILMYDIANEESFNAVQDWVTQIKTYSWDNAQVVLVGNKCDLEGDRIISTERGCHLANQLGLEFLETSAKENINVKTVFERLVDIICDKMSESLEADHSVGKSSNSGTRLTSEPQKVLTDQCQC 865
            KDA +DQNFDYMFK+LIIGNSSVGKTSFLFRYADDSFTSAFVSTVGIDFKVKTV++ DKR+KLQIWDTAGQERYRTITTAYYRGAMGFILMYD+ NEESFNAVQDWVTQIKTYSWDNAQVVLVGNKCDLE +R++STERG  LA+QLGLEF ETSAKENINVK VFERLVDIIC+KMSESL++D ++  +   GTRLT  P +  ++ CQC
Sbjct:   11 KDA-ADQNFDYMFKLLIIGNSSVGKTSFLFRYADDSFTSAFVSTVGIDFKVKTVFRQDKRVKLQIWDTAGQERYRTITTAYYRGAMGFILMYDVTNEESFNAVQDWVTQIKTYSWDNAQVVLVGNKCDLEDERVVSTERGKQLADQLGLEFFETSAKENINVKAVFERLVDIICEKMSESLDSDPTIVSNQRGGTRLTETPNQQASN-CQC 219
[Close]
BLAST of Ras-related protein Rab-3 vs. TrEMBL
Match: A0A1S3H822 (ras-related protein Rab-3 isoform X4 OS=Lingula unguis OX=7574 GN=LOC106152563 PE=4 SV=1)

HSP 1 Score: 358.607 bits (919), Expect = 3.416e-121
Identity = 172/211 (81.52%), Postives = 191/211 (90.52%), Query Frame = 2 
Query:  233 KDAGSDQNFDYMFKILIIGNSSVGKTSFLFRYADDSFTSAFVSTVGIDFKVKTVYKDDKRIKLQIWDTAGQERYRTITTAYYRGAMGFILMYDIANEESFNAVQDWVTQIKTYSWDNAQVVLVGNKCDLEGDRIISTERGCHLANQLGLEFLETSAKENINVKTVFERLVDIICDKMSESLEADHSVGKSSNSGTRLTSEPQKVLTDQCQC 865
            KDA +DQNFDYMFK+LIIGNSSVGKTSFLFRYADDSFTSAFVSTVGIDFKVKTV++ DKR+KLQIWDTAGQERYRTITTAYYRGAMGFILMYD+ NEESFNAVQDWVTQIKTYSWDNAQVVLVGNKCDLE +R++STERG  LA+QLGLEF ETSAKENINVK VFERLVDIIC+KMSESL++D ++  +   GTRLT  P +  ++ CQC
Sbjct:   19 KDA-ADQNFDYMFKLLIIGNSSVGKTSFLFRYADDSFTSAFVSTVGIDFKVKTVFRQDKRVKLQIWDTAGQERYRTITTAYYRGAMGFILMYDVTNEESFNAVQDWVTQIKTYSWDNAQVVLVGNKCDLEDERVVSTERGKQLADQLGLEFFETSAKENINVKAVFERLVDIICEKMSESLDSDPTIVSNQRGGTRLTETPNQQASN-CQC 227
[Close]
BLAST of Ras-related protein Rab-3 vs. TrEMBL
Match: A0A1S3H6M6 (ras-related protein Rab-3 isoform X1 OS=Lingula unguis OX=7574 GN=LOC106152563 PE=4 SV=1)

HSP 1 Score: 358.221 bits (918), Expect = 7.421e-121
Identity = 173/224 (77.23%), Postives = 193/224 (86.16%), Query Frame = 2 
Query:  209 FISTMGSTKDA-----GSDQNFDYMFKILIIGNSSVGKTSFLFRYADDSFTSAFVSTVGIDFKVKTVYKDDKRIKLQIWDTAGQERYRTITTAYYRGAMGFILMYDIANEESFNAVQDWVTQIKTYSWDNAQVVLVGNKCDLEGDRIISTERGCHLANQLGLEFLETSAKENINVKTVFERLVDIICDKMSESLEADHSVGKSSNSGTRLTSEPQKVLTDQCQC 865
            F   M S  D+      +DQNFDYMFK+LIIGNSSVGKTSFLFRYADDSFTSAFVSTVGIDFKVKTV++ DKR+KLQIWDTAGQERYRTITTAYYRGAMGFILMYD+ NEESFNAVQDWVTQIKTYSWDNAQVVLVGNKCDLE +R++STERG  LA+QLGLEF ETSAKENINVK VFERLVDIIC+KMSESL++D ++  +   GTRLT  P +  ++ CQC
Sbjct:   23 FYRKMASANDSKWQKDAADQNFDYMFKLLIIGNSSVGKTSFLFRYADDSFTSAFVSTVGIDFKVKTVFRQDKRVKLQIWDTAGQERYRTITTAYYRGAMGFILMYDVTNEESFNAVQDWVTQIKTYSWDNAQVVLVGNKCDLEDERVVSTERGKQLADQLGLEFFETSAKENINVKAVFERLVDIICEKMSESLDSDPTIVSNQRGGTRLTETPNQQASN-CQC 245
[Close]
BLAST of Ras-related protein Rab-3 vs. TrEMBL
Match: A0A0L8G4F2 (Uncharacterized protein OS=Octopus bimaculoides OX=37653 GN=OCBIM_22000262mg PE=4 SV=1)

HSP 1 Score: 357.066 bits (915), Expect = 8.571e-121
Identity = 173/211 (81.99%), Postives = 187/211 (88.63%), Query Frame = 2 
Query:  233 KDAGSDQNFDYMFKILIIGNSSVGKTSFLFRYADDSFTSAFVSTVGIDFKVKTVYKDDKRIKLQIWDTAGQERYRTITTAYYRGAMGFILMYDIANEESFNAVQDWVTQIKTYSWDNAQVVLVGNKCDLEGDRIISTERGCHLANQLGLEFLETSAKENINVKTVFERLVDIICDKMSESLEADHSVGKSSNSGTRLTSEPQKVLTDQCQC 865
            KDA +DQNFDYMFK+LIIGNSSVGKTSFLFRYADDSFTSAFVSTVGIDFKVKTV++ DKR+KLQIWDTAGQERYRTITTAYYRGAMGFILMYD+ NEESFNAVQDW TQIKTYSWDNAQVVLVGNKCDLE +R++STERG  LA+QLGLEF ETSAKENINVK VFERLVDIICDKMSESL++D ++  S   GTRLT  P       CQC
Sbjct:   11 KDA-ADQNFDYMFKLLIIGNSSVGKTSFLFRYADDSFTSAFVSTVGIDFKVKTVFRQDKRVKLQIWDTAGQERYRTITTAYYRGAMGFILMYDVTNEESFNAVQDWCTQIKTYSWDNAQVVLVGNKCDLEEERVVSTERGKQLADQLGLEFFETSAKENINVKAVFERLVDIICDKMSESLDSDPTLVNSQTKGTRLTENPNP-QNSSCQC 219
[Close]
BLAST of Ras-related protein Rab-3 vs. Ensembl Cavefish
Match: RAB3C (RAB3C, member RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:30269])

HSP 1 Score: 344.354 bits (882), Expect = 2.959e-119
Identity = 163/215 (75.81%), Postives = 177/215 (82.33%), Query Frame = 2 
Query:  221 MGSTKDAGSDQNFDYMFKILIIGNSSVGKTSFLFRYADDSFTSAFVSTVGIDFKVKTVYKDDKRIKLQIWDTAGQERYRTITTAYYRGAMGFILMYDIANEESFNAVQDWVTQIKTYSWDNAQVVLVGNKCDLEGDRIISTERGCHLANQLGLEFLETSAKENINVKTVFERLVDIICDKMSESLEADHSVGKSSNSGTRLTSEPQKVLTDQCQC 865
            M + +   SDQNFDYMFK+LIIGNSSVGKTSFLFRYADDSFTSAFVSTVGIDFKVKTVYK+DKRIKLQIWDTAGQERYRTITTAYYRGAMGFILMYDI NEESF AVQDW TQIKTYSWDNAQV+L GNKCD+E +R++S + G  LA QLG EF ETSAK+N+NVK  FERLVDIICDKMSESLE D +V   +    RLT  P       C C
Sbjct:    1 MAAAQKESSDQNFDYMFKLLIIGNSSVGKTSFLFRYADDSFTSAFVSTVGIDFKVKTVYKNDKRIKLQIWDTAGQERYRTITTAYYRGAMGFILMYDITNEESFGAVQDWSTQIKTYSWDNAQVILAGNKCDMEEERVVSVDSGRLLAEQLGFEFFETSAKDNVNVKQTFERLVDIICDKMSESLETDPTVTTGTQGNARLTDNPPPSQQPNCAC 215
[Close]
BLAST of Ras-related protein Rab-3 vs. Ensembl Cavefish
Match: rab3aa (ras-related protein Rab-3A-like [Source:NCBI gene;Acc:103026901])

HSP 1 Score: 337.421 bits (864), Expect = 1.784e-116
Identity = 159/207 (76.81%), Postives = 180/207 (86.96%), Query Frame = 2 
Query:  245 SDQNFDYMFKILIIGNSSVGKTSFLFRYADDSFTSAFVSTVGIDFKVKTVYKDDKRIKLQIWDTAGQERYRTITTAYYRGAMGFILMYDIANEESFNAVQDWVTQIKTYSWDNAQVVLVGNKCDLEGDRIISTERGCHLANQLGLEFLETSAKENINVKTVFERLVDIICDKMSESLEADHSVGKSSNSGTRLTSEPQKVLTDQCQC 865
            SDQNFDYMFKILIIGNSSVGKTSFLFRYADDSFT AFVSTVGIDFKVKT+Y++DKRIKLQIWDTAGQERYRTITTAYYRGAMGFILMYDI NE+SFNAVQDW TQIKTYSWDNAQV+LVGNKCD+E +R+++++RG  LA+QLG EF E SAK+NINVK  FERLVD+IC++MSESLE+  S       G +LT +PQ+   D C C
Sbjct:   15 SDQNFDYMFKILIIGNSSVGKTSFLFRYADDSFTPAFVSTVGIDFKVKTIYRNDKRIKLQIWDTAGQERYRTITTAYYRGAMGFILMYDITNEDSFNAVQDWSTQIKTYSWDNAQVLLVGNKCDIEDERLVASQRGRQLADQLGFEFFEASAKDNINVKQTFERLVDVICERMSESLESGDSSVTGGKQGPQLTEQPQRSHQD-CAC 220
[Close]
BLAST of Ras-related protein Rab-3 vs. Ensembl Cavefish
Match: rab3aa (ras-related protein Rab-3A-like [Source:NCBI gene;Acc:103026901])

HSP 1 Score: 337.421 bits (864), Expect = 2.230e-116
Identity = 159/207 (76.81%), Postives = 180/207 (86.96%), Query Frame = 2 
Query:  245 SDQNFDYMFKILIIGNSSVGKTSFLFRYADDSFTSAFVSTVGIDFKVKTVYKDDKRIKLQIWDTAGQERYRTITTAYYRGAMGFILMYDIANEESFNAVQDWVTQIKTYSWDNAQVVLVGNKCDLEGDRIISTERGCHLANQLGLEFLETSAKENINVKTVFERLVDIICDKMSESLEADHSVGKSSNSGTRLTSEPQKVLTDQCQC 865
            SDQNFDYMFKILIIGNSSVGKTSFLFRYADDSFT AFVSTVGIDFKVKT+Y++DKRIKLQIWDTAGQERYRTITTAYYRGAMGFILMYDI NE+SFNAVQDW TQIKTYSWDNAQV+LVGNKCD+E +R+++++RG  LA+QLG EF E SAK+NINVK  FERLVD+IC++MSESLE+  S       G +LT +PQ+   D C C
Sbjct:   22 SDQNFDYMFKILIIGNSSVGKTSFLFRYADDSFTPAFVSTVGIDFKVKTIYRNDKRIKLQIWDTAGQERYRTITTAYYRGAMGFILMYDITNEDSFNAVQDWSTQIKTYSWDNAQVLLVGNKCDIEDERLVASQRGRQLADQLGFEFFEASAKDNINVKQTFERLVDVICERMSESLESGDSSVTGGKQGPQLTEQPQRSHQD-CAC 227
[Close]
BLAST of Ras-related protein Rab-3 vs. Ensembl Cavefish
Match: rab3b (ras-related protein Rab-3B [Source:NCBI gene;Acc:103027359])

HSP 1 Score: 335.495 bits (859), Expect = 1.051e-115
Identity = 158/206 (76.70%), Postives = 183/206 (88.83%), Query Frame = 2 
Query:  242 GSDQNFDYMFKILIIGNSSVGKTSFLFRYADDSFTSAFVSTVGIDFKVKTVYKDDKRIKLQIWDTAGQERYRTITTAYYRGAMGFILMYDIANEESFNAVQDWVTQIKTYSWDNAQVVLVGNKCDLEGDRIISTERGCHLANQLGLEFLETSAKENINVKTVFERLVDIICDKMSESLEADHSVGKSSNSGTRLTSEPQKVLTDQC 859
            GSDQNFDYMFK+LIIGNSSVGKTSFLFRYADDSF+++FVSTVGIDFKVKTVY++DKR+KLQIWDTAGQERYRTITTAYYRGAMGFILMYDI NEESFNAVQDW TQIKTYSWDNAQV+LVGNKCD++ +R+I  E+G HLA+QLG E+ E SAKENINV+ VFERLVDIIC KMSE ++AD S+   + + TRLT +P ++  + C
Sbjct:   13 GSDQNFDYMFKLLIIGNSSVGKTSFLFRYADDSFSNSFVSTVGIDFKVKTVYRNDKRVKLQIWDTAGQERYRTITTAYYRGAMGFILMYDITNEESFNAVQDWATQIKTYSWDNAQVILVGNKCDMDDERVIPMEKGKHLADQLGFEYYEASAKENINVRQVFERLVDIICVKMSERVDADPSMVTGAKT-TRLTDKPAQLPQNCC 217
[Close]
BLAST of Ras-related protein Rab-3 vs. Ensembl Cavefish
Match: rab3ab (RAB3A, member RAS oncogene family [Source:NCBI gene;Acc:103043849])

HSP 1 Score: 333.183 bits (853), Expect = 1.026e-114
Identity = 158/207 (76.33%), Postives = 174/207 (84.06%), Query Frame = 2 
Query:  245 SDQNFDYMFKILIIGNSSVGKTSFLFRYADDSFTSAFVSTVGIDFKVKTVYKDDKRIKLQIWDTAGQERYRTITTAYYRGAMGFILMYDIANEESFNAVQDWVTQIKTYSWDNAQVVLVGNKCDLEGDRIISTERGCHLANQLGLEFLETSAKENINVKTVFERLVDIICDKMSESLEADHSVGKSSNSGTRLTSEPQKVLTDQCQC 865
            SDQNFDYMFKILIIGNSSVGKTSFLFRYADDSFT AFVSTVGIDFKVKT+Y++DKRIKLQIWDTAGQERYRTITTAYYRGAMGFILMYDI NEESF AVQDW TQIKTYSWDNAQV+LVGNKCD+E +R+++ ERG  L+  LG EF E SAK+NINVK  FERLVDIIC+KMSESL+A       +  G +LT +P     D C C
Sbjct:   15 SDQNFDYMFKILIIGNSSVGKTSFLFRYADDSFTPAFVSTVGIDFKVKTIYRNDKRIKLQIWDTAGQERYRTITTAYYRGAMGFILMYDITNEESFAAVQDWSTQIKTYSWDNAQVLLVGNKCDMEDERVVAAERGRQLSEHLGFEFFEASAKDNINVKQTFERLVDIICEKMSESLDAADPAVTGAKQGPQLTEQPAAPHQD-CAC 220
[Close]
BLAST of Ras-related protein Rab-3 vs. Ensembl Sea Lamprey
Match: rab3c (RAB3C, member RAS oncogene family [Source:ZFIN;Acc:ZDB-GENE-040718-263])

HSP 1 Score: 327.02 bits (837), Expect = 7.905e-113
Identity = 166/216 (76.85%), Postives = 182/216 (84.26%), Query Frame = 2 
Query:  233 KDAGSDQNFDYMFKILIIGNSSVGKTSFLFRYADDSFTSAFVSTVGIDFKVKTVYKDDKRIKLQIWDTAGQERYRTITTAYYRGAMGFILMYDIANEESFNAVQDWVTQIKTYSWDNAQVVLVGNKCDLEGDRIISTERGCHLANQLGLEFLETSAKENINVKTVFERLVDIICDKMSESL----EADHSVGKSSNSGTRLT-SEPQKVLTDQCQC 865
            KDA +DQNFDYMFK+LIIGNSSVGKTSFLFRYAD+SFTSAFVSTVGIDFKVKTVY+++KRIKLQIWDTAGQERYRTITTAYYRGAMGFILMYDI NE+SFNAV DW TQIKTYSWDNAQVVLVGNKCD+E DR++ TE+G  LA QLG EF ETSAK+NINVK  FERLVD+IC+KMSESL     A  +    S  GTRLT S PQ   +  C C
Sbjct:   19 KDA-ADQNFDYMFKLLIIGNSSVGKTSFLFRYADESFTSAFVSTVGIDFKVKTVYRNEKRIKLQIWDTAGQERYRTITTAYYRGAMGFILMYDITNEDSFNAVSDWSTQIKTYSWDNAQVVLVGNKCDMEDDRMVPTEQGRQLAEQLGFEFFETSAKDNINVKQTFERLVDVICEKMSESLDGDGAAAGAGAAGSKQGTRLTDSLPQS--SQACGC 231
[Close]
BLAST of Ras-related protein Rab-3 vs. Ensembl Sea Lamprey
Match: rab8a (RAB8A, member RAS oncogene family [Source:ZFIN;Acc:ZDB-GENE-070424-36])

HSP 1 Score: 208.379 bits (529), Expect = 1.291e-66
Identity = 98/205 (47.80%), Postives = 147/205 (71.71%), Query Frame = 2 
Query:  251 QNFDYMFKILIIGNSSVGKTSFLFRYADDSFTSAFVSTVGIDFKVKTVYKDDKRIKLQIWDTAGQERYRTITTAYYRGAMGFILMYDIANEESFNAVQDWVTQIKTYSWDNAQVVLVGNKCDLEGDRIISTERGCHLANQLGLEFLETSAKENINVKTVFERLVDIICDKMSESLEADHSVGKSSNSGTRLTSEPQKVLTDQCQC 865
            + +DY+FK+L+IG+S VGKT  LFR+++D+F S F+ST+GIDFK++T+  D K+IKLQIWDTAGQER+RTITTAYYRGAMG +L+YDI NE+SF  +++W+  I+ ++  + + +++GNKCD+   R ++ ERG  LA + G++F+ETSAK +INV+  F  L   I  KM   LE +++     ++  R+T+  Q   T   +C
Sbjct:    3 KTYDYLFKLLLIGDSGVGKTCVLFRFSEDAFNSTFISTIGIDFKIRTIDLDGKKIKLQIWDTAGQERFRTITTAYYRGAMGIMLVYDITNEKSFENIKNWIRNIEEHASADVEKMILGNKCDMNERRQVTRERGEKLAIEYGIKFMETSAKASINVEEAFFTLARDIKAKMDRKLEGNNT---PDSNAVRITAPSQGKKTSFFRC 204
[Close]
BLAST of Ras-related protein Rab-3 vs. Ensembl Sea Lamprey
Match: rab1aa (RAB1A, member RAS oncogene family a [Source:ZFIN;Acc:ZDB-GENE-090312-110])

HSP 1 Score: 188.348 bits (477), Expect = 7.779e-59
Identity = 90/204 (44.12%), Postives = 133/204 (65.20%), Query Frame = 2 
Query:  248 DQNFDYMFKILIIGNSSVGKTSFLFRYADDSFTSAFVSTVGIDFKVKTVYKDDKRIKLQIWDTAGQERYRTITTAYYRGAMGFILMYDIANEESFNAVQDWVTQIKTYSWDNAQVVLVGNKCDLEGDRIISTERGCHLANQLGLEFLETSAKENINVKTVFERLVDIICDKMSESLEADHSVGKSSNSGTRLTSEPQKVLTDQC 859
            +  +DY+FK+L+IG+S VGK+  L R+ADD++T +++ST+G+DFK++T+  D K IKLQIWDTAGQER+RTIT++YYRGA G I++YD+ ++ESFN V+ W+ +I  Y+ +N   +LVGNKCDL   +++        A+ L + FLETSAK   NV+  F  +   I  +M          GKS+    ++ S P K     C
Sbjct:    5 NPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQERFRTITSSYYRGAHGIIVVYDVTDQESFNNVKQWLQEIDRYASENVNKLLVGNKCDLTTKKVVDYTTAKEFADSLEIPFLETSAKNATNVEQAFMTMAAEIKKRMGPG-ATQAGAGKSN---VKIDSTPVKTGGGGC 204
[Close]
BLAST of Ras-related protein Rab-3 vs. Ensembl Sea Lamprey
Match: rab8a (RAB8A, member RAS oncogene family [Source:ZFIN;Acc:ZDB-GENE-070424-36])

HSP 1 Score: 176.792 bits (447), Expect = 2.683e-54
Identity = 90/187 (48.13%), Postives = 130/187 (69.52%), Query Frame = 2 
Query:  251 QNFDYMFKILIIGNSSVGKTSFLFRYADDSFTSAFVSTVGIDFKVKTV--YKDDKRIKLQIWDTAGQERYRTITTAYYRGAMGFILMYDIANEESFNAVQDWVTQIKTYSWDNAQVVLVGNKCDLEGDRIISTERGCHLANQLGLEFLETSAKENINVKTVFERLVDIICDKMSESLEADHSVGKSS 805
            +++D +FK+L+IG+S VGKT  LFR+++D+F S F+ST+G    V  V    D K+IKLQIWDTAGQER+RTITTAYYRGAMG +L+YDI NE+SF  +++W+  I+ ++  + Q  +VGNKCD+   R ++ +RG  LA    ++F+ETSAK +INV+  F  L   I  KM + +E + +   SS
Sbjct:    3 KSYDCLFKLLLIGDSGVGKTCVLFRFSEDAFNSTFISTIGGSRPVCQVCIRIDLKKIKLQIWDTAGQERFRTITTAYYRGAMGSMLVYDITNEKSFENIKNWIRNIEEHASADVQ-KMVGNKCDMNDRRQVTKDRGEKLAEDYNIQFMETSAKASINVEEAFFTLAREIKAKMDKKMEGNTAAENSS 188
[Close]
BLAST of Ras-related protein Rab-3 vs. Ensembl Sea Lamprey
Match: rab18b (RAB18B, member RAS oncogene family [Source:NCBI gene;Acc:445055])

HSP 1 Score: 153.68 bits (387), Expect = 1.924e-45
Identity = 75/162 (46.30%), Postives = 109/162 (67.28%), Query Frame = 2 
Query:  269 FKILIIGNSSVGKTSFLFRYADDSFTSAFVSTVGIDFKVKTVYKDDKRIKLQIWDTAGQERYRTITTAYYRGAMGFILMYDIANEESFNAVQDWVTQIKTYSWDNAQV-VLVGNKCDLEGDRIISTERGCHLANQLGLEFLETSAKENINVKTVFERLVDII 751
             KILIIG S VGK+S L R+ DD+F     +T+G+DFKVKT+  D  + KL IWDTAGQER+RT+T +YYRGA G IL+YD+   ++F  +++W+++++TY+  +  V +LVGNK D +G R++    G   A +  + F+E SAK    V+  FE LV+ I
Sbjct:    8 LKILIIGESGVGKSSLLLRFTDDTFDPELAATIGVDFKVKTIAVDGNKAKLAIWDTAGQERFRTLTPSYYRGAQGVILVYDVTKRDTFLKLENWLSELETYTTRSDIVKMLVGNKIDKDG-RVLDRTEGLKFARKHSMLFIEASAKTRDGVQCAFEELVEKI 168
[Close]
BLAST of Ras-related protein Rab-3 vs. Ensembl Yeast
Match: SEC4 (Rab family GTPase; essential for vesicle-mediated exocytic secretion and autophagy; associates with the exocyst component Sec15p and may regulate polarized delivery of transport vesicles to the exocyst at the plasma membrane [Source:SGD;Acc:S000001889])

HSP 1 Score: 187.193 bits (474), Expect = 1.474e-58
Identity = 84/175 (48.00%), Postives = 131/175 (74.86%), Query Frame = 2 
Query:  239 AGSDQNFDYMFKILIIGNSSVGKTSFLFRYADDSFTSAFVSTVGIDFKVKTVYKDDKRIKLQIWDTAGQERYRTITTAYYRGAMGFILMYDIANEESFNAVQDWVTQIKTYSWDNAQVVLVGNKCDLEGDRIISTERGCHLANQLGLEFLETSAKENINVKTVFERLVDIICDKM 763
            +G+ +++D + KIL+IG+S VGK+  L R+ +D F  +F++T+GIDFK+KTV  + K++KLQ+WDTAGQER+RTITTAYYRGAMG IL+YD+ +E +F  ++ W   +  ++ D AQ++LVGNK D+E  R+++ ++G  LA +LG+ F+E+SAK + NV  +F  L  +I +K+
Sbjct:   11 SGNGKSYDSIMKILLIGDSGVGKSCLLVRFVEDKFNPSFITTIGIDFKIKTVDINGKKVKLQLWDTAGQERFRTITTAYYRGAMGIILVYDVTDERTFTNIKQWFKTVNEHANDEAQLLLVGNKSDME-TRVVTADQGEALAKELGIPFIESSAKNDDNVNEIFFTLAKLIQEKI 184
[Close]
BLAST of Ras-related protein Rab-3 vs. Ensembl Yeast
Match: YPT1 (Rab family GTPase; involved in the ER-to-Golgi step of the secretory pathway; complex formation with the Rab escort protein Mrs6p is required for prenylation of Ypt1p by type II protein geranylgeranyltransferase (Bet2p-Bet4p); binds to unspliced HAC1 mRNA; regulates the unfolded protein response (UPR) by promoting the decay of HAC1 RNA; localizes to the early Golgi, the transitional Golgi and ER membranes, pre-autophagosomal structures, and cytoplasmic vesicles [Source:SGD;Acc:S000001856])

HSP 1 Score: 181.8 bits (460), Expect = 1.538e-56
Identity = 82/171 (47.95%), Postives = 124/171 (72.51%), Query Frame = 2 
Query:  257 FDYMFKILIIGNSSVGKTSFLFRYADDSFTSAFVSTVGIDFKVKTVYKDDKRIKLQIWDTAGQERYRTITTAYYRGAMGFILMYDIANEESFNAVQDWVTQIKTYSWDNAQVVLVGNKCDLEGDRIISTERGCHLANQLGLEFLETSAKENINVKTVFERLVDIICDKMSE 769
            +DY+FK+L+IGNS VGK+  L R++DD++T+ ++ST+G+DFK+KTV  D K +KLQIWDTAGQER+RTIT++YYRG+ G I++YD+ ++ESFN V+ W+ +I  Y+      +LVGNKCDL+  R++  +     A+   + FLETSA ++ NV+  F  +   I + MS+
Sbjct:    5 YDYLFKLLLIGNSGVGKSCLLLRFSDDTYTNDYISTIGVDFKIKTVELDGKTVKLQIWDTAGQERFRTITSSYYRGSHGIIIVYDVTDQESFNGVKMWLQEIDRYATSTVLKLLVGNKCDLKDKRVVEYDVAKEFADANKMPFLETSALDSTNVEDAFLTMARQIKESMSQ 175
[Close]
BLAST of Ras-related protein Rab-3 vs. Ensembl Yeast
Match: YPT31 (Rab family GTPase; involved in the exocytic pathway; mediates intra-Golgi traffic or the budding of post-Golgi vesicles from the trans-Golgi; YPT31 has a paralog, YPT32, that arose from the whole genome duplication; localizes to the transitional and late Golgi [Source:SGD;Acc:S000000833])

HSP 1 Score: 158.303 bits (399), Expect = 3.013e-47
Identity = 85/209 (40.67%), Postives = 127/209 (60.77%), Query Frame = 2 
Query:  227 STKDAGSDQNFDYMFKILIIGNSSVGKTSFLFRYADDSFTSAFVSTVGIDFKVKTVYKDDKRIKLQIWDTAGQERYRTITTAYYRGAMGFILMYDIANEESFNAVQDWVTQIKTYSWDNAQVVLVGNKCDLEGDRIISTERGCHLANQLGLEFLETSAKENINVKTVFERLVDIICDKMSE-SLEADHSVGKSSNSGTRLTSEPQKVLT 850
            S++D G D  +D +FKI++IG+S VGK++ L R+  + F     ST+G++F  +T+  D KRIK QIWDTAGQERYR IT+AYYRGA+G +++YDI+   S+     W+++++  + DN  V L+GNK DL   R + TE     A +  L F ETSA  + NV   FE L++ I  K+S+  ++   S    + +G    + P   LT
Sbjct:    2 SSEDYGYD--YDLLFKIVLIGDSGVGKSNLLSRFTKNEFNMDSKSTIGVEFATRTLEIDGKRIKAQIWDTAGQERYRAITSAYYRGAVGALIVYDISKSSSYENCNHWLSELRENADDNVAVGLIGNKSDLAHLRAVPTEESKTFAQENQLLFTETSALNSENVDKAFEELINTIYQKVSKHQMDLGDSSANGNANGASAPNGPTISLT 208
[Close]
BLAST of Ras-related protein Rab-3 vs. Ensembl Yeast
Match: YPT32 (Rab family GTPase involved in the exocytic pathway; mediates intra-Golgi traffic or the budding of post-Golgi vesicles from the trans-Golgi; protein abundance increases in response to DNA replication stress; YPT32 has a paralog, YPT31, that arose from the whole genome duplication [Source:SGD;Acc:S000003178])

HSP 1 Score: 153.295 bits (386), Expect = 2.433e-45
Identity = 81/197 (41.12%), Postives = 124/197 (62.94%), Query Frame = 2 
Query:  227 STKDAGSDQNFDYMFKILIIGNSSVGKTSFLFRYADDSFTSAFVSTVGIDFKVKTVYKDDKRIKLQIWDTAGQERYRTITTAYYRGAMGFILMYDIANEESFNAVQDWVTQIKTYSWDNAQVVLVGNKCDLEGDRIISTERGCHLANQLGLEFLETSAKENINVKTVFERLVDIICDKMSESLEADHSVGKSSNSGT 817
            S +D G D  +DY+FKI++IG+S VGK++ L R+  D F     ST+G++F  +T+  ++K+IK QIWDTAGQERYR IT+AYYRGA+G +++YDI+   S+     W+T+++  + DN  V L+GNK DL   R + T+   + A +  + F ETSA  + NV   F  L+  I   +S+  + D S   ++N G+
Sbjct:    2 SNEDYGYD--YDYLFKIVLIGDSGVGKSNLLSRFTTDEFNIESKSTIGVEFATRTIEVENKKIKAQIWDTAGQERYRAITSAYYRGAVGALIVYDISKSSSYENCNHWLTELRENADDNVAVGLIGNKSDLAHLRAVPTDEAKNFAMENQMLFTETSALNSDNVDKAFRELIVAIFQMVSKH-QVDLSGSGTNNMGS 195
[Close]
BLAST of Ras-related protein Rab-3 vs. Ensembl Yeast
Match: YPT6 (Rab family GTPase; required for endosome-to-Golgii, intra-Golgi retrograde, and retrograde Golgi-to-ER transport; temporarily at the Golgi, dissociating into the cytosol on arrival of the late Golgi GTPase Ypt32p; Golgi-localized form is GTP bound, while cytosolic form is GDP-bound; required for delivery of Atg9p to the phagophore assembly site during autophagy under heat stress, with Ypt6p for starvation induced autophagy and for the CVT pathway; homolog of mammalian Rab6 [Source:SGD;Acc:S000004252])

HSP 1 Score: 142.51 bits (358), Expect = 3.197e-41
Identity = 81/205 (39.51%), Postives = 119/205 (58.05%), Query Frame = 2 
Query:  269 FKILIIGNSSVGKTSFLFRYADDSFTSAFVSTVGIDFKVKTVYKDDKRIKLQIWDTAGQERYRTITTAYYRGAMGFILMYDIANEESFNAVQDWVTQIKTYSWD-NAQVVLVGNKCDLEGDRIISTERGCHLANQLGLE-FLETSAKENINVKTVFERLVDIICD-KMSESLEADHSVGKSSN---SGTRLTSEPQKVLTDQCQC 865
            +KI+ +G   VGKTS + R+  D+F   + +T+GIDF  KT+Y DDK I+LQ+WDTAGQER+R++  +Y R +   I++YDI   +SF  +  W+  +K    D N  + +VGNK DL  +R ISTE G   A  LG + F+ETS K   NVK +F+++   + + + SES   D     S+N    G    S  ++     CQC
Sbjct:   11 YKIVFLGEQGVGKTSLITRFMYDTFDDHYQATIGIDFLSKTMYLDDKTIRLQLWDTAGQERFRSLIPSYIRDSRVAIIVYDITKRKSFEYIDKWIEDVKNERGDENVILCIVGNKSDLSDERQISTEEGEKKAKLLGAKIFMETSTKAGYNVKALFKKIAKSLPEFQNSESTPLDSENANSANQNKPGVIDISTAEEQEQSACQC 215
[Close]
BLAST of Ras-related protein Rab-3 vs. Ensembl Nematostella
Match: EDO34944 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SMW8])

HSP 1 Score: 335.88 bits (860), Expect = 2.947e-116
Identity = 162/212 (76.42%), Postives = 184/212 (86.79%), Query Frame = 2 
Query:  233 KDAGSDQNFDYMFKILIIGNSSVGKTSFLFRYADDSFTSAFVSTVGIDFKVKTVYKDDKRIKLQIWDTAGQERYRTITTAYYRGAMGFILMYDIANEESFNAVQDWVTQIKTYSWDNAQVVLVGNKCDLEGDRIISTERGCHLANQLGLEFLETSAKENINVKTVFERLVDIICDKMSESLEADHSVGKSSNSG-TRLTSEPQKVLTDQCQC 865
            KDA +DQNFDYMFK+LIIGNS+VGKTSFLFRYADDSFTSAFVSTVGIDFKVKTV+++DKR+KLQIWDTAGQERYRTITTAYYRGAMGFILMYDI NEESF AVQDW TQ+KTYSW NAQV+LVGNKCD+E +R++S +RG  LA+QLGLEF ETSAK+N NVK VFERLVDIICDKMS+SL+ D ++      G T+LT+E  K   D C C
Sbjct:   11 KDA-ADQNFDYMFKLLIIGNSAVGKTSFLFRYADDSFTSAFVSTVGIDFKVKTVFRNDKRVKLQIWDTAGQERYRTITTAYYRGAMGFILMYDITNEESFQAVQDWSTQVKTYSWANAQVILVGNKCDMEEERVVSYDRGKQLADQLGLEFYETSAKDNTNVKKVFERLVDIICDKMSQSLDTDPTIVSGQKPGTTKLTAERPKQNQDNCAC 221
[Close]
BLAST of Ras-related protein Rab-3 vs. Ensembl Nematostella
Match: EDO41018 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S5I6])

HSP 1 Score: 206.838 bits (525), Expect = 7.802e-66
Identity = 96/196 (48.98%), Postives = 144/196 (73.47%), Query Frame = 2 
Query:  251 QNFDYMFKILIIGNSSVGKTSFLFRYADDSFTSAFVSTVGIDFKVKTVYKDDKRIKLQIWDTAGQERYRTITTAYYRGAMGFILMYDIANEESFNAVQDWVTQIKTYSWDNAQVVLVGNKCDLEGDRIISTERGCHLANQLGLEFLETSAKENINVKTVFERLVDIICDKMSESLEADHSVGKSSNSGTRLTSEPQ 838
            + +D++FK+L+IG+S VGKT  LFR+++D+F S F+ST+GIDFK++T+  D K+IKLQIWDTAGQER+RTITTAYYRGAMG +L+YDI N++SF  +++W+  I+ ++  + + +++GNKCD+E  R +S ERG  LA + G++F+ETSAK +INV+  F  L   I  KM + LE  +    +S    ++T E +
Sbjct:    3 KTYDFLFKLLLIGDSGVGKTCVLFRFSEDAFNSTFISTIGIDFKIRTIELDGKKIKLQIWDTAGQERFRTITTAYYRGAMGIMLVYDITNDKSFENIKNWIRNIEEHASQDVEKMVLGNKCDMEDRRQVSKERGEQLAVEYGIKFMETSAKASINVEEAFFTLARDIKLKMDKKLENSNP---ASTGAVKITHEKE 195
[Close]
BLAST of Ras-related protein Rab-3 vs. Ensembl Nematostella
Match: EDO47471 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RMA6])

HSP 1 Score: 200.675 bits (509), Expect = 1.540e-63
Identity = 88/172 (51.16%), Postives = 132/172 (76.74%), Query Frame = 2 
Query:  245 SDQNFDYMFKILIIGNSSVGKTSFLFRYADDSFTSAFVSTVGIDFKVKTVYKDDKRIKLQIWDTAGQERYRTITTAYYRGAMGFILMYDIANEESFNAVQDWVTQIKTYSWDNAQVVLVGNKCDLEGDRIISTERGCHLANQLGLEFLETSAKENINVKTVFERLVDIICDK 760
            + +++DY+FK+L+IG+S VGKT  LFR++DD+F + F+ST+GIDFK+KT+    K+IKLQIWDTAGQER+ TITT+YYRGAMG +L+YDI  E++F+ +  W+  I+ ++ ++ + +++GNKCD++  RI+S ERG  +A + G+ FLETSAK NIN++  F+ L   I  K
Sbjct:    2 AKKSYDYLFKLLLIGDSGVGKTCILFRFSDDAFNTTFISTIGIDFKIKTIEMQGKKIKLQIWDTAGQERFHTITTSYYRGAMGIMLVYDITQEKTFDNISKWLRNIEEHANEDVEKMILGNKCDMDDRRIVSRERGEQIAREHGIRFLETSAKTNINIEQAFQYLAQDILKK 173
[Close]
BLAST of Ras-related protein Rab-3 vs. Ensembl Nematostella
Match: EDO40845 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S5Z2])

HSP 1 Score: 191.815 bits (486), Expect = 3.030e-60
Identity = 89/182 (48.90%), Postives = 131/182 (71.98%), Query Frame = 2 
Query:  245 SDQNFDYMFKILIIGNSSVGKTSFLFRYADDSFTSAFVSTVGIDFKVKTVYKDDKRIKLQIWDTAGQERYRTITTAYYRGAMGFILMYDIANEESFNAVQDWVTQIKTYSWDNAQVVLVGNKCDLEGDRIISTERGCHLANQLGLEFLETSAKENINVKTVF----ERLVDIICDKMSESLE 778
            +++  D  FK+L+IG+S VGKT  +FR+AD++F  +F+ST+GIDFK+KT+    K+IKLQIWDTAGQER+ TITTAYYRGAMG +L+YD+ NE+SF+ +  W+ +I  ++ ++ + +LVGNKCD+   R+IS  +G  LA+  G+ F+ETSA  NINV+  F    E +++ +C    E  E
Sbjct:    2 ANKKSDLFFKLLLIGDSGVGKTCIIFRFADNTFNPSFISTIGIDFKIKTLELGGKKIKLQIWDTAGQERFHTITTAYYRGAMGIMLVYDVTNEKSFSNISKWLKKIDDHANEDVKRMLVGNKCDMYDKRVISQTKGEQLASSYGISFIETSALSNINVEKSFVVLTEDILNAVCPPTVEETE 183
[Close]
BLAST of Ras-related protein Rab-3 vs. Ensembl Nematostella
Match: EDO40167 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S806])

HSP 1 Score: 191.815 bits (486), Expect = 6.359e-60
Identity = 87/183 (47.54%), Postives = 127/183 (69.40%), Query Frame = 2 
Query:  248 DQNFDYMFKILIIGNSSVGKTSFLFRYADDSFTSAFVSTVGIDFKVKTVYKDDKRIKLQIWDTAGQERYRTITTAYYRGAMGFILMYDIANEESFNAVQDWVTQIKTYSWDNAQVVLVGNKCDLEGDRIISTERGCHLANQLGLEFLETSAKENINVKTVFERLVDIICDKMSESLEADHSVG 796
            +  +DY+FK+L+IG+S VGK+  L R+ADD++T +++ST+G+DFK++T+  D K IKLQIWDTAGQER+RTIT++YYRGA G I++YD+ ++ESFN V+ W+ +I  Y+ +N   +LVGNKCDL   +++        A  LG+ FLETSAK   NV+  F  +   I ++M  S  A    G
Sbjct:    5 NPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQERFRTITSSYYRGAHGIIVVYDVTDQESFNNVKQWLQEIDRYACENVNKLLVGNKCDLTTKKVVDFTTAKEYAESLGVPFLETSAKNATNVEQAFMTMAAEIKNRMGPS-PAPQGAG 186
[Close]
BLAST of Ras-related protein Rab-3 vs. Ensembl Medaka
Match: rab3c (RAB3C, member RAS oncogene family [Source:NCBI gene;Acc:101166306])

HSP 1 Score: 335.495 bits (859), Expect = 9.614e-116
Identity = 164/220 (74.55%), Postives = 181/220 (82.27%), Query Frame = 2 
Query:  221 MGSTKDA-----GSDQNFDYMFKILIIGNSSVGKTSFLFRYADDSFTSAFVSTVGIDFKVKTVYKDDKRIKLQIWDTAGQERYRTITTAYYRGAMGFILMYDIANEESFNAVQDWVTQIKTYSWDNAQVVLVGNKCDLEGDRIISTERGCHLANQLGLEFLETSAKENINVKTVFERLVDIICDKMSESLEADHSVGKSSNSGTRLTSEPQKVLTDQCQC 865
            M +T+DA     G DQNFDYMFK+LIIGNSSVGKTSFLFRYADD+FTSAFVSTVGIDFKVKTVYK+DKRIKLQIWDTAGQERYRTITTAYYRGAMGFILMYDI NEESF AVQDW TQIKTYSWDNAQVVL GNKCD+E +R++S E G  LA QLG EF ETSAK+NINVK  FERLVD+ICDKMSESL+ D +V   + +  +LT     +    C C
Sbjct:    1 MAATQDAKGKGEGGDQNFDYMFKLLIIGNSSVGKTSFLFRYADDAFTSAFVSTVGIDFKVKTVYKNDKRIKLQIWDTAGQERYRTITTAYYRGAMGFILMYDITNEESFGAVQDWSTQIKTYSWDNAQVVLAGNKCDMEEERVVSVESGRLLAEQLGFEFFETSAKDNINVKQTFERLVDLICDKMSESLDTDPAVTTGAPTA-KLTDSAPPLQQQGCNC 219
[Close]
BLAST of Ras-related protein Rab-3 vs. Ensembl Medaka
Match: rab3c (RAB3C, member RAS oncogene family [Source:NCBI gene;Acc:101166306])

HSP 1 Score: 335.88 bits (860), Expect = 9.979e-116
Identity = 164/220 (74.55%), Postives = 181/220 (82.27%), Query Frame = 2 
Query:  221 MGSTKDA-----GSDQNFDYMFKILIIGNSSVGKTSFLFRYADDSFTSAFVSTVGIDFKVKTVYKDDKRIKLQIWDTAGQERYRTITTAYYRGAMGFILMYDIANEESFNAVQDWVTQIKTYSWDNAQVVLVGNKCDLEGDRIISTERGCHLANQLGLEFLETSAKENINVKTVFERLVDIICDKMSESLEADHSVGKSSNSGTRLTSEPQKVLTDQCQC 865
            M +T+DA     G DQNFDYMFK+LIIGNSSVGKTSFLFRYADD+FTSAFVSTVGIDFKVKTVYK+DKRIKLQIWDTAGQERYRTITTAYYRGAMGFILMYDI NEESF AVQDW TQIKTYSWDNAQVVL GNKCD+E +R++S E G  LA QLG EF ETSAK+NINVK  FERLVD+ICDKMSESL+ D +V   + +  +LT     +    C C
Sbjct:    8 MAATQDAKGKGEGGDQNFDYMFKLLIIGNSSVGKTSFLFRYADDAFTSAFVSTVGIDFKVKTVYKNDKRIKLQIWDTAGQERYRTITTAYYRGAMGFILMYDITNEESFGAVQDWSTQIKTYSWDNAQVVLAGNKCDMEEERVVSVESGRLLAEQLGFEFFETSAKDNINVKQTFERLVDLICDKMSESLDTDPAVTTGAPTA-KLTDSAPPLQQQGCNC 226
[Close]
BLAST of Ras-related protein Rab-3 vs. Ensembl Medaka
Match: rab3c (RAB3C, member RAS oncogene family [Source:NCBI gene;Acc:101166306])

HSP 1 Score: 335.109 bits (858), Expect = 1.835e-115
Identity = 164/220 (74.55%), Postives = 181/220 (82.27%), Query Frame = 2 
Query:  221 MGSTKDA-----GSDQNFDYMFKILIIGNSSVGKTSFLFRYADDSFTSAFVSTVGIDFKVKTVYKDDKRIKLQIWDTAGQERYRTITTAYYRGAMGFILMYDIANEESFNAVQDWVTQIKTYSWDNAQVVLVGNKCDLEGDRIISTERGCHLANQLGLEFLETSAKENINVKTVFERLVDIICDKMSESLEADHSVGKSSNSGTRLTSEPQKVLTDQCQC 865
            M +T+DA     G DQNFDYMFK+LIIGNSSVGKTSFLFRYADD+FTSAFVSTVGIDFKVKTVYK+DKRIKLQIWDTAGQERYRTITTAYYRGAMGFILMYDI NEESF AVQDW TQIKTYSWDNAQVVL GNKCD+E +R++S E G  LA QLG EF ETSAK+NINVK  FERLVD+ICDKMSESL+ D +V   + +  +LT     +    C C
Sbjct:    7 MAATQDAKGKGEGGDQNFDYMFKLLIIGNSSVGKTSFLFRYADDAFTSAFVSTVGIDFKVKTVYKNDKRIKLQIWDTAGQERYRTITTAYYRGAMGFILMYDITNEESFGAVQDWSTQIKTYSWDNAQVVLAGNKCDMEEERVVSVESGRLLAEQLGFEFFETSAKDNINVKQTFERLVDLICDKMSESLDTDPAVTTGAPTA-KLTDSAPPLQQQGCNC 225
[Close]
BLAST of Ras-related protein Rab-3 vs. Ensembl Medaka
Match: rab3ab (RAB3A, member RAS oncogene family [Source:NCBI gene;Acc:101167944])

HSP 1 Score: 334.339 bits (856), Expect = 3.604e-115
Identity = 158/207 (76.33%), Postives = 175/207 (84.54%), Query Frame = 2 
Query:  245 SDQNFDYMFKILIIGNSSVGKTSFLFRYADDSFTSAFVSTVGIDFKVKTVYKDDKRIKLQIWDTAGQERYRTITTAYYRGAMGFILMYDIANEESFNAVQDWVTQIKTYSWDNAQVVLVGNKCDLEGDRIISTERGCHLANQLGLEFLETSAKENINVKTVFERLVDIICDKMSESLEADHSVGKSSNSGTRLTSEPQKVLTDQCQC 865
            SDQNFDYMFKILIIGNSSVGKTSFLFRYADDSFT AFVSTVGIDFKVKT+Y++DKRIKLQIWDTAGQERYRTITTAYYRGAMGFILMYDI NE+SFNAVQDW TQIKTYSWDNAQV+LVGNKCD+E +R++S +RG  L+  LG EF E SAK+NINVK  FERLVDIIC+KMSESL+A       +  G +LT +P     D C C
Sbjct:   14 SDQNFDYMFKILIIGNSSVGKTSFLFRYADDSFTPAFVSTVGIDFKVKTIYRNDKRIKLQIWDTAGQERYRTITTAYYRGAMGFILMYDITNEDSFNAVQDWSTQIKTYSWDNAQVLLVGNKCDMEDERVVSADRGRQLSEHLGFEFFEASAKDNINVKQTFERLVDIICEKMSESLDAGDPAVTGAKQGPQLTEQPAPPHQD-CAC 219
[Close]
BLAST of Ras-related protein Rab-3 vs. Ensembl Medaka
Match: rab3ab (RAB3A, member RAS oncogene family [Source:NCBI gene;Acc:101167944])

HSP 1 Score: 334.339 bits (856), Expect = 3.604e-115
Identity = 158/207 (76.33%), Postives = 175/207 (84.54%), Query Frame = 2 
Query:  245 SDQNFDYMFKILIIGNSSVGKTSFLFRYADDSFTSAFVSTVGIDFKVKTVYKDDKRIKLQIWDTAGQERYRTITTAYYRGAMGFILMYDIANEESFNAVQDWVTQIKTYSWDNAQVVLVGNKCDLEGDRIISTERGCHLANQLGLEFLETSAKENINVKTVFERLVDIICDKMSESLEADHSVGKSSNSGTRLTSEPQKVLTDQCQC 865
            SDQNFDYMFKILIIGNSSVGKTSFLFRYADDSFT AFVSTVGIDFKVKT+Y++DKRIKLQIWDTAGQERYRTITTAYYRGAMGFILMYDI NE+SFNAVQDW TQIKTYSWDNAQV+LVGNKCD+E +R++S +RG  L+  LG EF E SAK+NINVK  FERLVDIIC+KMSESL+A       +  G +LT +P     D C C
Sbjct:   14 SDQNFDYMFKILIIGNSSVGKTSFLFRYADDSFTPAFVSTVGIDFKVKTIYRNDKRIKLQIWDTAGQERYRTITTAYYRGAMGFILMYDITNEDSFNAVQDWSTQIKTYSWDNAQVLLVGNKCDMEDERVVSADRGRQLSEHLGFEFFEASAKDNINVKQTFERLVDIICEKMSESLDAGDPAVTGAKQGPQLTEQPAPPHQD-CAC 219
[Close]
BLAST of Ras-related protein Rab-3 vs. Planmine SMEST
Match: SMESG000034019.1 (SMESG000034019.1)

HSP 1 Score: 352.443 bits (903), Expect = 1.548e-122
Identity = 168/213 (78.87%), Postives = 186/213 (87.32%), Query Frame = 2 
Query:  227 STKDAGSDQNFDYMFKILIIGNSSVGKTSFLFRYADDSFTSAFVSTVGIDFKVKTVYKDDKRIKLQIWDTAGQERYRTITTAYYRGAMGFILMYDIANEESFNAVQDWVTQIKTYSWDNAQVVLVGNKCDLEGDRIISTERGCHLANQLGLEFLETSAKENINVKTVFERLVDIICDKMSESLEADHSVGKSSNSGTRLTSEPQKVLTDQCQC 865
            S     +DQNFDYMFK+LIIGNSSVGKTSFLFRYADDSFTSAFVSTVGIDFKVKT+ + DK++KLQIWDTAGQERYRTITTAYYRGAMGFILMYDI NEESFNAVQDWVTQIKTYSWDNAQVVLVGNK DL+ +R+IS +RG  LA+QLGLEF ETSAKEN++VK+VFERLVDIICDKMSESL+ D S+  + N GTRL  E  K L + CQC
Sbjct:    2 SANSKDTDQNFDYMFKLLIIGNSSVGKTSFLFRYADDSFTSAFVSTVGIDFKVKTIVRRDKKVKLQIWDTAGQERYRTITTAYYRGAMGFILMYDITNEESFNAVQDWVTQIKTYSWDNAQVVLVGNKVDLDYERVISIDRGRQLASQLGLEFFETSAKENLHVKSVFERLVDIICDKMSESLDTDPSIVNNPNKGTRLADETNKALPNDCQC 214
[Close]
BLAST of Ras-related protein Rab-3 vs. Planmine SMEST
Match: SMESG000037789.1 (SMESG000037789.1)

HSP 1 Score: 325.094 bits (832), Expect = 8.268e-112
Identity = 154/207 (74.40%), Postives = 176/207 (85.02%), Query Frame = 2 
Query:  245 SDQNFDYMFKILIIGNSSVGKTSFLFRYADDSFTSAFVSTVGIDFKVKTVYKDDKRIKLQIWDTAGQERYRTITTAYYRGAMGFILMYDIANEESFNAVQDWVTQIKTYSWDNAQVVLVGNKCDLEGDRIISTERGCHLANQLGLEFLETSAKENINVKTVFERLVDIICDKMSESLEADHSVGKSSNSGTRLTSEPQKVLTDQCQC 865
            SDQNFDYMFK+L+IGNSSVGKTSFLFRYAD+SF+SAFV+TVGIDFKVKTV++ DKR+KLQIWDTAGQERYRTITTAYYRGAMGFILMYD+ NEESFNAV DW+ QIKTYSWDNAQVVLVGNKCDLE D++IS  RG  LA+QLG+EF E+SAKENINVK VFERLVDIIC+KM ES+E +  +      G +L  +  +     CQC
Sbjct:    6 SDQNFDYMFKLLLIGNSSVGKTSFLFRYADNSFSSAFVATVGIDFKVKTVFRHDKRVKLQIWDTAGQERYRTITTAYYRGAMGFILMYDVTNEESFNAVHDWIMQIKTYSWDNAQVVLVGNKCDLEDDKVISISRGQQLADQLGVEFFESSAKENINVKIVFERLVDIICEKMMESIEGEPYLANGGVKGKKL-HQASETDGQGCQC 211
[Close]
BLAST of Ras-related protein Rab-3 vs. Planmine SMEST
Match: SMESG000055715.1 (SMESG000055715.1)

HSP 1 Score: 300.442 bits (768), Expect = 2.196e-102
Identity = 139/176 (78.98%), Postives = 161/176 (91.48%), Query Frame = 2 
Query:  266 MFKILIIGNSSVGKTSFLFRYADDSFTSAFVSTVGIDFKVKTVYKDDKRIKLQIWDTAGQERYRTITTAYYRGAMGFILMYDIANEESFNAVQDWVTQIKTYSWDNAQVVLVGNKCDLEGDRIISTERGCHLANQLGLEFLETSAKENINVKTVFERLVDIICDKMSESLEADHSV 793
            MFK+L+IGNSSVGKTSFLFRYAD+SFTSAFV+TVGIDFKVKTV++ DKR+KLQIWDTAGQERYRTITTAYYRGAMGFILMYDI NE++FN VQDWVTQIKTYSWDNAQ++LVGNKCDLE +R +STER   LA+ L L+F ETSAKENINVK VFERLVD+ICDKM+E +++  ++
Sbjct:    1 MFKLLLIGNSSVGKTSFLFRYADNSFTSAFVATVGIDFKVKTVFRQDKRVKLQIWDTAGQERYRTITTAYYRGAMGFILMYDITNEDTFNCVQDWVTQIKTYSWDNAQIILVGNKCDLEENRAVSTERAKQLADYLNLDFFETSAKENINVKAVFERLVDVICDKMAECIDSSPAL 176
[Close]
BLAST of Ras-related protein Rab-3 vs. Planmine SMEST
Match: SMESG000035214.1 (SMESG000035214.1)

HSP 1 Score: 194.126 bits (492), Expect = 2.167e-60
Identity = 86/182 (47.25%), Postives = 134/182 (73.63%), Query Frame = 2 
Query:  245 SDQNFDYMFKILIIGNSSVGKTSFLFRYADDSFTSAFVSTVGIDFKVKTVYKDDKRIKLQIWDTAGQERYRTITTAYYRGAMGFILMYDIANEESFNAVQDWVTQIKTYSWDNAQVVLVGNKCDLEGDRIISTERGCHLANQLGLEFLETSAKENINVKTVFERLVDIICDKMSESLEADHS 790
            + +++D +FK+L+IG+S VGKT  LFRYADD+F++ F+ST+GIDFK+KT+  + KRIKLQIWDTAGQER+ TIT +YYRGAMG +L+YD+ N++SF+ +  W+T I++++ ++ + ++V NK D+E  R+++ + G ++A    + FLE SAK  +NV   FE+L   I  K+  + E+  S
Sbjct:    2 AKKSYDLLFKLLLIGDSGVGKTCLLFRYADDTFSTTFISTIGIDFKIKTIEMNGKRIKLQIWDTAGQERFHTITMSYYRGAMGIMLVYDVTNKKSFDNISKWLTNIQSHASESVEKLIVANKIDMEEKRVVTKDIGENIAVANKVSFLEVSAKTGVNVPQAFEKLTMAILAKVPNTKESAES 183
[Close]
BLAST of Ras-related protein Rab-3 vs. Planmine SMEST
Match: SMESG000026178.1 (SMESG000026178.1)

HSP 1 Score: 191.815 bits (486), Expect = 1.263e-59
Identity = 90/205 (43.90%), Postives = 143/205 (69.76%), Query Frame = 2 
Query:  251 QNFDYMFKILIIGNSSVGKTSFLFRYADDSFTSAFVSTVGIDFKVKTVYKDDKRIKLQIWDTAGQERYRTITTAYYRGAMGFILMYDIANEESFNAVQDWVTQIKTYSWDNAQVVLVGNKCDLEGDRIISTERGCHLANQLGLEFLETSAKENINVKTVFERLVDIICDKMSESLEADHSVGKSSNSGTRLTSEPQKVLTDQCQC 865
            + +D++FK+L+IG+S VGKTS LFR+++D+F + F++T+GIDFK++T+  + K+IKLQIWDTAGQER+RTITTAYYRGAMG +L+YD+ +E+SFN +  W+  I  ++  + + +L+GNK D+   R + T+ G  LA   G++F+ETSAK   NV   F +L   I +KM +  +    V  +S+  T+  S+ ++  + +C+ 
Sbjct:    3 KPYDHLFKLLLIGDSGVGKTSVLFRFSEDNFNATFIATIGIDFKIRTIDINGKKIKLQIWDTAGQERFRTITTAYYRGAMGIMLVYDVTSEKSFNNINQWIDNITQHANADVEKMLLGNKADMNDQRQVPTDTGRELAQSHGIKFMETSAKTGQNVDEAFRQLALDIKNKMEKRSDLTGVVPPTSHKITK-ESKRRRAFSFKCEI 206
The following BLAST results are available for this feature:
BLAST of Ras-related protein Rab-3 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
RAB3C1.586e-12076.92RAB3C, member RAS oncogene family [Source:HGNC Sym... [more]
RAB3B7.849e-11476.30RAB3B, member RAS oncogene family [Source:HGNC Sym... [more]
RAB3A1.178e-11376.44RAB3A, member RAS oncogene family [Source:HGNC Sym... [more]
RAB3D1.885e-11080.85RAB3D, member RAS oncogene family [Source:HGNC Sym... [more]
RAB3D1.885e-11080.85RAB3D, member RAS oncogene family [Source:HGNC Sym... [more]
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BLAST of Ras-related protein Rab-3 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
rab-31.436e-11576.44Ras-related protein Rab-3 [Source:UniProtKB/Swiss... [more]
rab-33.601e-11576.44Ras-related protein Rab-3 [Source:UniProtKB/Swiss... [more]
rab-81.526e-6552.91RAB family; Rab8 [Source:UniProtKB/TrEMBL;Acc:G5E... [more]
rab-81.526e-6552.91RAB family; Rab8 [Source:UniProtKB/TrEMBL;Acc:G5E... [more]
rab-18.582e-6347.00RAB family [Source:UniProtKB/TrEMBL;Acc:Q9UAQ6][more]
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BLAST of Ras-related protein Rab-3 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Rab32.198e-12179.15gene:FBgn0005586 transcript:FBtr0473383[more]
Rab32.198e-12179.15gene:FBgn0005586 transcript:FBtr0088257[more]
Rab86.426e-6451.11gene:FBgn0262518 transcript:FBtr0308833[more]
Rab86.426e-6451.11gene:FBgn0262518 transcript:FBtr0074921[more]
Rab107.650e-6451.35gene:FBgn0015789 transcript:FBtr0077337[more]
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BLAST of Ras-related protein Rab-3 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
rab3c1.042e-11674.89RAB3C, member RAS oncogene family [Source:ZFIN;Acc... [more]
rab3c1.042e-11674.89RAB3C, member RAS oncogene family [Source:ZFIN;Acc... [more]
rab3c1.564e-11674.89RAB3C, member RAS oncogene family [Source:ZFIN;Acc... [more]
rab3ab2.599e-11475.85RAB3A, member RAS oncogene family, b [Source:ZFIN;... [more]
rab3aa6.876e-11370.59RAB3A, member RAS oncogene family, a [Source:ZFIN;... [more]
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BLAST of Ras-related protein Rab-3 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
rab3a2.367e-11476.81RAB3A, member RAS oncogene family [Source:NCBI gen... [more]
rab3b4.834e-11476.81RAB3B, member RAS oncogene family [Source:NCBI gen... [more]
RAB3C1.084e-11387.64RAB3C, member RAS oncogene family [Source:NCBI gen... [more]
RAB3C1.943e-11387.64RAB3C, member RAS oncogene family [Source:NCBI gen... [more]
tekt17.655e-11174.54tektin 1 [Source:Xenbase;Acc:XB-GENE-5929242][more]
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BLAST of Ras-related protein Rab-3 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Rab3c1.361e-11876.02RAB3C, member RAS oncogene family [Source:MGI Symb... [more]
Rab3c2.974e-11876.02RAB3C, member RAS oncogene family [Source:MGI Symb... [more]
Rab3d4.720e-11575.93RAB3D, member RAS oncogene family [Source:MGI Symb... [more]
Rab3d4.720e-11575.93RAB3D, member RAS oncogene family [Source:MGI Symb... [more]
Rab3a2.111e-11476.33Ras-related protein Rab-3A [Source:UniProtKB/Swis... [more]
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BLAST of Ras-related protein Rab-3 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|P25228|RAB3_DROME2.203e-12079.15Ras-related protein Rab-3 OS=Drosophila melanogast... [more]
sp|Q96E17|RAB3C_HUMAN7.616e-12076.92Ras-related protein Rab-3C OS=Homo sapiens OX=9606... [more]
sp|P10949|RAB3C_BOVIN1.747e-11976.92Ras-related protein Rab-3C OS=Bos taurus OX=9913 G... [more]
sp|P62824|RAB3C_RAT9.520e-11876.02Ras-related protein Rab-3C OS=Rattus norvegicus OX... [more]
sp|P62823|RAB3C_MOUSE9.520e-11876.02Ras-related protein Rab-3C OS=Mus musculus OX=1009... [more]
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BLAST of Ras-related protein Rab-3 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A1S3H6N12.621e-12181.52ras-related protein Rab-3 isoform X5 OS=Lingula un... [more]
A0A1S3H6L22.937e-12181.52ras-related protein Rab-3 isoform X6 OS=Lingula un... [more]
A0A1S3H8223.416e-12181.52ras-related protein Rab-3 isoform X4 OS=Lingula un... [more]
A0A1S3H6M67.421e-12177.23ras-related protein Rab-3 isoform X1 OS=Lingula un... [more]
A0A0L8G4F28.571e-12181.99Uncharacterized protein OS=Octopus bimaculoides OX... [more]
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BLAST of Ras-related protein Rab-3 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
RAB3C2.959e-11975.81RAB3C, member RAS oncogene family [Source:HGNC Sym... [more]
rab3aa1.784e-11676.81ras-related protein Rab-3A-like [Source:NCBI gene;... [more]
rab3aa2.230e-11676.81ras-related protein Rab-3A-like [Source:NCBI gene;... [more]
rab3b1.051e-11576.70ras-related protein Rab-3B [Source:NCBI gene;Acc:1... [more]
rab3ab1.026e-11476.33RAB3A, member RAS oncogene family [Source:NCBI gen... [more]
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BLAST of Ras-related protein Rab-3 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5
Match NameE-valueIdentityDescription
rab3c7.905e-11376.85RAB3C, member RAS oncogene family [Source:ZFIN;Acc... [more]
rab8a1.291e-6647.80RAB8A, member RAS oncogene family [Source:ZFIN;Acc... [more]
rab1aa7.779e-5944.12RAB1A, member RAS oncogene family a [Source:ZFIN;A... [more]
rab8a2.683e-5448.13RAB8A, member RAS oncogene family [Source:ZFIN;Acc... [more]
rab18b1.924e-4546.30RAB18B, member RAS oncogene family [Source:NCBI ge... [more]
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BLAST of Ras-related protein Rab-3 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 5
Match NameE-valueIdentityDescription
SEC41.474e-5848.00Rab family GTPase; essential for vesicle-mediated ... [more]
YPT11.538e-5647.95Rab family GTPase; involved in the ER-to-Golgi ste... [more]
YPT313.013e-4740.67Rab family GTPase; involved in the exocytic pathwa... [more]
YPT322.433e-4541.12Rab family GTPase involved in the exocytic pathway... [more]
YPT63.197e-4139.51Rab family GTPase; required for endosome-to-Golgii... [more]
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BLAST of Ras-related protein Rab-3 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO349442.947e-11676.42Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO410187.802e-6648.98Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO474711.540e-6351.16Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO408453.030e-6048.90Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO401676.359e-6047.54Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Ras-related protein Rab-3 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
rab3c9.614e-11674.55RAB3C, member RAS oncogene family [Source:NCBI gen... [more]
rab3c9.979e-11674.55RAB3C, member RAS oncogene family [Source:NCBI gen... [more]
rab3c1.835e-11574.55RAB3C, member RAS oncogene family [Source:NCBI gen... [more]
rab3ab3.604e-11576.33RAB3A, member RAS oncogene family [Source:NCBI gen... [more]
rab3ab3.604e-11576.33RAB3A, member RAS oncogene family [Source:NCBI gen... [more]
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BLAST of Ras-related protein Rab-3 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000034019.11.548e-12278.87SMESG000034019.1[more]
SMESG000037789.18.268e-11274.40SMESG000037789.1[more]
SMESG000055715.12.196e-10278.98SMESG000055715.1[more]
SMESG000035214.12.167e-6047.25SMESG000035214.1[more]
SMESG000026178.11.263e-5943.90SMESG000026178.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30027710 ID=SMED30027710|Name=Ras-related protein Rab-3|organism=Schmidtea mediterranea sexual|type=transcript|length=1090bp
TGCACACACGATGCAATACATACAATACTTGTATTTACACACTCAATTTA
AGTAGAAATACATTAGAAATACTTACACTCTCGAAATGAGAGTTGTACTT
AGTTTATCTATTCTTTGACAGATTAATACGATTCCAAAATTAAGAAAGCA
AGTAAAATAACTTCAAACTAATTCTTGAAGAAATATTGATTTCAATTCTT
TTGCTATTTTTATTAGCACAATGGGATCTACAAAGGATGCTGGTTCAGAT
CAAAACTTTGATTATATGTTTAAAATTTTAATTATTGGAAATTCATCAGT
TGGGAAAACTTCATTTTTATTTCGGTATGCCGATGATAGTTTCACGTCAG
CGTTTGTATCAACTGTAGGCATTGATTTCAAGGTGAAGACAGTATATAAA
GATGACAAAAGAATTAAATTGCAAATATGGGACACTGCCGGTCAAGAGCG
ATATCGCACTATCACAACAGCGTATTACCGAGGAGCAATGGGGTTTATTT
TAATGTATGACATTGCCAATGAAGAATCTTTTAATGCTGTTCAAGATTGG
GTAACGCAAATCAAAACCTATTCTTGGGATAATGCACAAGTTGTGTTAGT
CGGTAATAAATGTGACTTGGAGGGTGATAGGATTATATCAACAGAAAGAG
GTTGCCATCTGGCTAATCAATTGGGTTTAGAATTTCTTGAAACTTCAGCG
AAAGAAAATATCAATGTTAAAACGGTTTTCGAAAGATTAGTAGATATTAT
TTGTGACAAAATGTCAGAGAGTTTAGAAGCTGATCATTCAGTTGGTAAAA
GCTCCAATTCTGGAACTCGTCTTACCAGTGAACCTCAGAAAGTTCTCACT
GATCAGTGTCAGTGCTAGAGTGTAAAACGTTTTAGTTTGTCTAATCTGAA
ATAAATTATATTTCCCCATGTTAGAAATGATATTTACGGTTTATTTACCA
AGCTGCTTTATGAATGTTAGTTCCACTAAAATTGTTTCTGTTTTTATTGG
TTGTCTGAAATATTCTTTTTCGCGTAATCGTTTACCAGAGTTGTTTATTT
ATTGTCCTTCAAAATAAACAGCTGTAACTTTTTGTAAATG
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protein sequence of SMED30027710-orf-1

>SMED30027710-orf-1 ID=SMED30027710-orf-1|Name=SMED30027710-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=216bp
MGSTKDAGSDQNFDYMFKILIIGNSSVGKTSFLFRYADDSFTSAFVSTVG
IDFKVKTVYKDDKRIKLQIWDTAGQERYRTITTAYYRGAMGFILMYDIAN
EESFNAVQDWVTQIKTYSWDNAQVVLVGNKCDLEGDRIISTERGCHLANQ
LGLEFLETSAKENINVKTVFERLVDIICDKMSESLEADHSVGKSSNSGTR
LTSEPQKVLTDQCQC*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000017photoreceptor neuron
PLANA:0000099neuron
PLANA:0000418head
Vocabulary: INTERPRO
TermDefinition
IPR005225Small_GTP-bd_dom
IPR027417P-loop_NTPase
IPR001806Small_GTPase
Vocabulary: molecular function
TermDefinition
GO:0005525GTP binding
GO:0000166nucleotide binding
GO:0003924GTPase activity
Vocabulary: biological process
TermDefinition
GO:0007264small GTPase mediated signal transduction
GO:0006810transport
GO:0006887exocytosis
GO:0007269neurotransmitter secretion
GO:0015031protein transport
GO:0016192vesicle-mediated transport
GO:0031630regulation of synaptic vesicle fusion to presynaptic active zone membrane
GO:0032482Rab protein signal transduction
GO:0048172regulation of short-term neuronal synaptic plasticity
GO:0048789cytoskeletal matrix organization at active zone
GO:0048790maintenance of presynaptic active zone structure
Vocabulary: cellular component
TermDefinition
GO:0008021synaptic vesicle
GO:0030054cell junction
GO:0031410cytoplasmic vesicle
GO:0031982vesicle
GO:0045202synapse
GO:0048786presynaptic active zone
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
NoneNo IPR availablePRINTSPR00449RASTRNSFRMNGcoord: 58..80
score: 55.35
coord: 40..56
score: 30.65
coord: 120..133
score: 54.13
coord: 155..177
score: 43.24
coord: 17..38
score: 42.14
NoneNo IPR availableSMARTSM00174rho_sub_3coord: 19..180
e-value: 7.0E-15
score: 65.4
NoneNo IPR availableSMARTSM00176ran_sub_2coord: 22..215
e-value: 1.1E-4
score: 17.8
NoneNo IPR availableSMARTSM00175rab_sub_5coord: 17..180
e-value: 1.0E-93
score: 327.4
NoneNo IPR availableSMARTSM00173ras_sub_4coord: 17..180
e-value: 3.3E-29
score: 113.0
NoneNo IPR availableGENE3DG3DSA:3.40.50.300coord: 3..183
e-value: 3.0E-65
score: 221.0
NoneNo IPR availablePANTHERPTHR24073FAMILY NOT NAMEDcoord: 6..212
NoneNo IPR availablePANTHERPTHR24073:SF853RAS-RELATED PROTEIN RAB-3coord: 6..212
NoneNo IPR availablePROSITEPS51419RABcoord: 12..215
score: 34.963
IPR001806Small GTPasePFAMPF00071Rascoord: 18..177
e-value: 6.3E-61
score: 204.7
IPR005225Small GTP-binding protein domainTIGRFAMTIGR00231TIGR00231coord: 15..171
e-value: 3.5E-28
score: 96.4
IPR027417P-loop containing nucleoside triphosphate hydrolaseSUPERFAMILYSSF52540P-loop containing nucleoside triphosphate hydrolasescoord: 12..185