PCI domain-containing protein 2

Overview
NamePCI domain-containing protein 2
Smed IDSMED30027678
Length (bp)1339
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of PCI domain-containing protein 2 (SMED30027678) t-SNE clustered cells

Violin plots show distribution of expression levels for PCI domain-containing protein 2 (SMED30027678) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of PCI domain-containing protein 2 (SMED30027678) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for PCI domain-containing protein 2 (SMED30027678) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30027678

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 1

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
X1 cellSMED30027678SMESG000007339.1 SmedASXL_011201SmedAsxl_ww_GCZZ01PMID:26114597
Zhu et al., 2015		FACS sorted cell population asexual adult RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of PCI domain-containing protein 2 vs. Ensembl Human
Match: PCID2 (PCI domain containing 2 [Source:HGNC Symbol;Acc:HGNC:25653])

HSP 1 Score: 355.91 bits (912), Expect = 1.484e-119
Identity = 181/396 (45.71%), Postives = 257/396 (64.90%), Query Frame = 1 
Query:   82 QMTIETFISMVAKNVKALNGEELAKLFDLNDRHIQDPTLIPFIPEKMKMGKQFVPWREMIVSHLNVLTHLNNKDLKGALEEQFNLIEIFSDLFEQIKDDNWFLPVMTVLTVDLRCLAHAMDYGIDSQVKHHSSAGENMKRVADCLMRLFRKCVSDSRSNVETSKKMGMMALCNQLFKIFFTISQLNLCKSLILAIENLGIIDKFSICQQVTYNYYVGRKCMFDDNFQKANESLTFAFENCHRDYVKNKRLILIYLIPVKMLLGNFPTDKLLVKYNLKEFSGVVKSVRIGDLCNLEAELNINGPFFISCGVYLILEKLKYIAYRNLFKTVSTMIGSHMISISAFSDALKFVGVSDIDIDETECILANLIFENKIKGYLAHQQQKLVMSKTNAFPSIS 1269
             +TI  ++  V + + + +G   A+L      H+ +P L    PE+        P+ EM  +HL     + N D   A + Q  +++ F   F+  K++NW LPVM  + +DLR  A+  D  +  + K  S  G+ +++ A+ LM  FR C SD+R+ +E SKK GM+ L NQLFKI+F I++L+LCK LI AI++  + D +S  Q+VTY YYVGRK MFD +F++A E L+FAFE+CHR   KNKR+ILIYL+PVKMLLG+ PT +LL KY+L +F+ V ++V  G+L  L   L  +  FFI CG++LILEKLK I YRNLFK V  ++ +H +S+ AF  ALKF+ V D+DIDE +CILANLI+   +KGY++HQ QKLV+SK N FP +S
Sbjct:    3 HITINQYLQQVYEAIDSRDGASCAELVSFKHPHVANPRLQMASPEEKCQQVLEPPYDEMFAAHLRCTYAVGNHDFIEAYKCQTVIVQSFLRAFQAHKEENWALPVMYAVALDLRVFANNADQQLVKKGK--SKVGDMLEKAAELLMSCFRVCASDTRAGIEDSKKWGMLFLVNQLFKIYFKINKLHLCKPLIRAIDSSNLKDDYSTAQRVTYKYYVGRKAMFDSDFKQAEEYLSFAFEHCHRSSQKNKRMILIYLLPVKMLLGHMPTVELLKKYHLMQFAEVTRAVSEGNLLLLHEALAKHEAFFIRCGIFLILEKLKIITYRNLFKKVYLLLKTHQLSLDAFLVALKFMQVEDVDIDEVQCILANLIYMGHVKGYISHQHQKLVVSKQNPFPPLS 396
[Close]
BLAST of PCI domain-containing protein 2 vs. Ensembl Human
Match: PCID2 (PCI domain containing 2 [Source:HGNC Symbol;Acc:HGNC:25653])

HSP 1 Score: 355.91 bits (912), Expect = 1.484e-119
Identity = 181/396 (45.71%), Postives = 257/396 (64.90%), Query Frame = 1 
Query:   82 QMTIETFISMVAKNVKALNGEELAKLFDLNDRHIQDPTLIPFIPEKMKMGKQFVPWREMIVSHLNVLTHLNNKDLKGALEEQFNLIEIFSDLFEQIKDDNWFLPVMTVLTVDLRCLAHAMDYGIDSQVKHHSSAGENMKRVADCLMRLFRKCVSDSRSNVETSKKMGMMALCNQLFKIFFTISQLNLCKSLILAIENLGIIDKFSICQQVTYNYYVGRKCMFDDNFQKANESLTFAFENCHRDYVKNKRLILIYLIPVKMLLGNFPTDKLLVKYNLKEFSGVVKSVRIGDLCNLEAELNINGPFFISCGVYLILEKLKYIAYRNLFKTVSTMIGSHMISISAFSDALKFVGVSDIDIDETECILANLIFENKIKGYLAHQQQKLVMSKTNAFPSIS 1269
             +TI  ++  V + + + +G   A+L      H+ +P L    PE+        P+ EM  +HL     + N D   A + Q  +++ F   F+  K++NW LPVM  + +DLR  A+  D  +  + K  S  G+ +++ A+ LM  FR C SD+R+ +E SKK GM+ L NQLFKI+F I++L+LCK LI AI++  + D +S  Q+VTY YYVGRK MFD +F++A E L+FAFE+CHR   KNKR+ILIYL+PVKMLLG+ PT +LL KY+L +F+ V ++V  G+L  L   L  +  FFI CG++LILEKLK I YRNLFK V  ++ +H +S+ AF  ALKF+ V D+DIDE +CILANLI+   +KGY++HQ QKLV+SK N FP +S
Sbjct:    3 HITINQYLQQVYEAIDSRDGASCAELVSFKHPHVANPRLQMASPEEKCQQVLEPPYDEMFAAHLRCTYAVGNHDFIEAYKCQTVIVQSFLRAFQAHKEENWALPVMYAVALDLRVFANNADQQLVKKGK--SKVGDMLEKAAELLMSCFRVCASDTRAGIEDSKKWGMLFLVNQLFKIYFKINKLHLCKPLIRAIDSSNLKDDYSTAQRVTYKYYVGRKAMFDSDFKQAEEYLSFAFEHCHRSSQKNKRMILIYLLPVKMLLGHMPTVELLKKYHLMQFAEVTRAVSEGNLLLLHEALAKHEAFFIRCGIFLILEKLKIITYRNLFKKVYLLLKTHQLSLDAFLVALKFMQVEDVDIDEVQCILANLIYMGHVKGYISHQHQKLVVSKQNPFPPLS 396
[Close]
BLAST of PCI domain-containing protein 2 vs. Ensembl Human
Match: PCID2 (PCI domain containing 2 [Source:HGNC Symbol;Acc:HGNC:25653])

HSP 1 Score: 355.91 bits (912), Expect = 1.484e-119
Identity = 181/396 (45.71%), Postives = 257/396 (64.90%), Query Frame = 1 
Query:   82 QMTIETFISMVAKNVKALNGEELAKLFDLNDRHIQDPTLIPFIPEKMKMGKQFVPWREMIVSHLNVLTHLNNKDLKGALEEQFNLIEIFSDLFEQIKDDNWFLPVMTVLTVDLRCLAHAMDYGIDSQVKHHSSAGENMKRVADCLMRLFRKCVSDSRSNVETSKKMGMMALCNQLFKIFFTISQLNLCKSLILAIENLGIIDKFSICQQVTYNYYVGRKCMFDDNFQKANESLTFAFENCHRDYVKNKRLILIYLIPVKMLLGNFPTDKLLVKYNLKEFSGVVKSVRIGDLCNLEAELNINGPFFISCGVYLILEKLKYIAYRNLFKTVSTMIGSHMISISAFSDALKFVGVSDIDIDETECILANLIFENKIKGYLAHQQQKLVMSKTNAFPSIS 1269
             +TI  ++  V + + + +G   A+L      H+ +P L    PE+        P+ EM  +HL     + N D   A + Q  +++ F   F+  K++NW LPVM  + +DLR  A+  D  +  + K  S  G+ +++ A+ LM  FR C SD+R+ +E SKK GM+ L NQLFKI+F I++L+LCK LI AI++  + D +S  Q+VTY YYVGRK MFD +F++A E L+FAFE+CHR   KNKR+ILIYL+PVKMLLG+ PT +LL KY+L +F+ V ++V  G+L  L   L  +  FFI CG++LILEKLK I YRNLFK V  ++ +H +S+ AF  ALKF+ V D+DIDE +CILANLI+   +KGY++HQ QKLV+SK N FP +S
Sbjct:    3 HITINQYLQQVYEAIDSRDGASCAELVSFKHPHVANPRLQMASPEEKCQQVLEPPYDEMFAAHLRCTYAVGNHDFIEAYKCQTVIVQSFLRAFQAHKEENWALPVMYAVALDLRVFANNADQQLVKKGK--SKVGDMLEKAAELLMSCFRVCASDTRAGIEDSKKWGMLFLVNQLFKIYFKINKLHLCKPLIRAIDSSNLKDDYSTAQRVTYKYYVGRKAMFDSDFKQAEEYLSFAFEHCHRSSQKNKRMILIYLLPVKMLLGHMPTVELLKKYHLMQFAEVTRAVSEGNLLLLHEALAKHEAFFIRCGIFLILEKLKIITYRNLFKKVYLLLKTHQLSLDAFLVALKFMQVEDVDIDEVQCILANLIYMGHVKGYISHQHQKLVVSKQNPFPPLS 396
[Close]
BLAST of PCI domain-containing protein 2 vs. Ensembl Human
Match: PCID2 (PCI domain containing 2 [Source:HGNC Symbol;Acc:HGNC:25653])

HSP 1 Score: 351.288 bits (900), Expect = 1.141e-117
Identity = 179/388 (46.13%), Postives = 253/388 (65.21%), Query Frame = 1 
Query:  106 SMVAKNVKALNGEELAKLFDLNDRHIQDPTLIPFIPEKMKMGKQFVPWREMIVSHLNVLTHLNNKDLKGALEEQFNLIEIFSDLFEQIKDDNWFLPVMTVLTVDLRCLAHAMDYGIDSQVKHHSSAGENMKRVADCLMRLFRKCVSDSRSNVETSKKMGMMALCNQLFKIFFTISQLNLCKSLILAIENLGIIDKFSICQQVTYNYYVGRKCMFDDNFQKANESLTFAFENCHRDYVKNKRLILIYLIPVKMLLGNFPTDKLLVKYNLKEFSGVVKSVRIGDLCNLEAELNINGPFFISCGVYLILEKLKYIAYRNLFKTVSTMIGSHMISISAFSDALKFVGVSDIDIDETECILANLIFENKIKGYLAHQQQKLVMSKTNAFPSIS 1269
             +V + + + +G   A+L      H+ +P L    PE+        P+ EM  +HL     + N D   A + Q  +++ F   F+  K++NW LPVM  + +DLR  A+  D  +  + K  S  G+ +++ A+ LM  FR C SD+R+ +E SKK GM+ L NQLFKI+F I++L+LCK LI AI++  + D +S  Q+VTY YYVGRK MFD +F++A E L+FAFE+CHR   KNKR+ILIYL+PVKMLLG+ PT +LL KY+L +F+ V ++V  G+L  L   L  +  FFI CG++LILEKLK I YRNLFK V  ++ +H +S+ AF  ALKF+ V D+DIDE +CILANLI+   +KGY++HQ QKLV+SK N FP +S
Sbjct:    9 QLVYEAIDSRDGASCAELVSFKHPHVANPRLQMASPEEKCQQVLEPPYDEMFAAHLRCTYAVGNHDFIEAYKCQTVIVQSFLRAFQAHKEENWALPVMYAVALDLRVFANNADQQLVKKGK--SKVGDMLEKAAELLMSCFRVCASDTRAGIEDSKKWGMLFLVNQLFKIYFKINKLHLCKPLIRAIDSSNLKDDYSTAQRVTYKYYVGRKAMFDSDFKQAEEYLSFAFEHCHRSSQKNKRMILIYLLPVKMLLGHMPTVELLKKYHLMQFAEVTRAVSEGNLLLLHEALAKHEAFFIRCGIFLILEKLKIITYRNLFKKVYLLLKTHQLSLDAFLVALKFMQVEDVDIDEVQCILANLIYMGHVKGYISHQHQKLVVSKQNPFPPLS 394
[Close]
BLAST of PCI domain-containing protein 2 vs. Ensembl Human
Match: PCID2 (PCI domain containing 2 [Source:HGNC Symbol;Acc:HGNC:25653])

HSP 1 Score: 351.288 bits (900), Expect = 1.141e-117
Identity = 179/388 (46.13%), Postives = 253/388 (65.21%), Query Frame = 1 
Query:  106 SMVAKNVKALNGEELAKLFDLNDRHIQDPTLIPFIPEKMKMGKQFVPWREMIVSHLNVLTHLNNKDLKGALEEQFNLIEIFSDLFEQIKDDNWFLPVMTVLTVDLRCLAHAMDYGIDSQVKHHSSAGENMKRVADCLMRLFRKCVSDSRSNVETSKKMGMMALCNQLFKIFFTISQLNLCKSLILAIENLGIIDKFSICQQVTYNYYVGRKCMFDDNFQKANESLTFAFENCHRDYVKNKRLILIYLIPVKMLLGNFPTDKLLVKYNLKEFSGVVKSVRIGDLCNLEAELNINGPFFISCGVYLILEKLKYIAYRNLFKTVSTMIGSHMISISAFSDALKFVGVSDIDIDETECILANLIFENKIKGYLAHQQQKLVMSKTNAFPSIS 1269
             +V + + + +G   A+L      H+ +P L    PE+        P+ EM  +HL     + N D   A + Q  +++ F   F+  K++NW LPVM  + +DLR  A+  D  +  + K  S  G+ +++ A+ LM  FR C SD+R+ +E SKK GM+ L NQLFKI+F I++L+LCK LI AI++  + D +S  Q+VTY YYVGRK MFD +F++A E L+FAFE+CHR   KNKR+ILIYL+PVKMLLG+ PT +LL KY+L +F+ V ++V  G+L  L   L  +  FFI CG++LILEKLK I YRNLFK V  ++ +H +S+ AF  ALKF+ V D+DIDE +CILANLI+   +KGY++HQ QKLV+SK N FP +S
Sbjct:    9 QLVYEAIDSRDGASCAELVSFKHPHVANPRLQMASPEEKCQQVLEPPYDEMFAAHLRCTYAVGNHDFIEAYKCQTVIVQSFLRAFQAHKEENWALPVMYAVALDLRVFANNADQQLVKKGK--SKVGDMLEKAAELLMSCFRVCASDTRAGIEDSKKWGMLFLVNQLFKIYFKINKLHLCKPLIRAIDSSNLKDDYSTAQRVTYKYYVGRKAMFDSDFKQAEEYLSFAFEHCHRSSQKNKRMILIYLLPVKMLLGHMPTVELLKKYHLMQFAEVTRAVSEGNLLLLHEALAKHEAFFIRCGIFLILEKLKIITYRNLFKKVYLLLKTHQLSLDAFLVALKFMQVEDVDIDEVQCILANLIYMGHVKGYISHQHQKLVVSKQNPFPPLS 394
[Close]
BLAST of PCI domain-containing protein 2 vs. Ensembl Celegans
Match: C27F2.10 (PCI domain-containing protein 2 homolog [Source:UniProtKB/Swiss-Prot;Acc:Q95QU0])

HSP 1 Score: 318.546 bits (815), Expect = 3.550e-105
Identity = 169/384 (44.01%), Postives = 246/384 (64.06%), Query Frame = 1 
Query:  136 NGEELAKLFDLNDRHIQDPTL-IPFIPEKMKMGK--QFVPWREMIVSHLNVLTHLN-NKDLKGALEEQFNLIEIFS-DLFEQIKDDNWFLPVMTVLTVDLRCLAHAMDYGIDSQVKHHSSAGENMKRVADCLMRLFRKCVSDSRSNVETSKKMGMMALCNQLFKIFFTISQLNLCKSLILAIENLG-IIDKFSICQQVTYNYYVGRKCMFDDNFQKANESLTFAFENCHRDYVKNKRLILIYLIPVKMLLGNFPTDKLLVKYNLKEFSGVVKSVRIGDLCNLEAELNINGPFFISCGVYLILEKLKYIAYRNLFKTVSTMIGSHMISISAFSDALKFVGVSDIDIDETECILANLIFENKIKGYLAHQQQKLVMSKTNAFPSIS 1269
            NGE+++K     D H Q+P + I     + K  +  +   + E++  HL+VL +++  +DL  A   Q  +I++F+ ++ ++ KD+NWFLP+   L  DLR L+   +  +    +  S+A    +  A  +   +R CVSD  +   T+KK+ M+ + NQLF+I+F I++LNL K LI AI+N G +   F +  +V YNY++GRK MFD +   A +SL +AF NC  D + NKR ILIYLIPVKM LG+ PT +LL +Y L EF  VV  V+ G+L  L+  L  N  FFI CG++L+LEKL+ I +R LFK VS ++G+  I + AF  AL+FVGV+D+D+DE ECI+ANLI   KIKGYL+HQ QKLV+SK NAFP++S
Sbjct:   25 NGEKISKFVSTYDEHAQEPFMHIEAYGSRSKRCRVSEDEVFDEIVCLHLHVLYNIHVAQDLITAQSTQIQIIQLFNKEILQKRKDENWFLPIFYRLCTDLRWLSKGAEACVSGDDEGDSNANSFFESAAKAITECYRTCVSDVHAEEGTTKKVAMLNMTNQLFQIYFQINKLNLLKPLIRAIDNCGSLYHDFLMSDKVAYNYFLGRKAMFDADLNLAEKSLLYAFRNCPADSMSNKRKILIYLIPVKMFLGHMPTSQLLHEYRLDEFQDVVAGVKDGNLAQLDGALAANEAFFIKCGIFLMLEKLRMITFRTLFKKVSQIVGTAQIPLDAFQTALRFVGVTDVDMDELECIIANLIASKKIKGYLSHQHQKLVISKMNAFPTLS 408
[Close]
BLAST of PCI domain-containing protein 2 vs. Ensembl Celegans
Match: C27F2.10 (PCI domain-containing protein 2 homolog [Source:UniProtKB/Swiss-Prot;Acc:Q95QU0])

HSP 1 Score: 318.546 bits (815), Expect = 3.550e-105
Identity = 169/384 (44.01%), Postives = 246/384 (64.06%), Query Frame = 1 
Query:  136 NGEELAKLFDLNDRHIQDPTL-IPFIPEKMKMGK--QFVPWREMIVSHLNVLTHLN-NKDLKGALEEQFNLIEIFS-DLFEQIKDDNWFLPVMTVLTVDLRCLAHAMDYGIDSQVKHHSSAGENMKRVADCLMRLFRKCVSDSRSNVETSKKMGMMALCNQLFKIFFTISQLNLCKSLILAIENLG-IIDKFSICQQVTYNYYVGRKCMFDDNFQKANESLTFAFENCHRDYVKNKRLILIYLIPVKMLLGNFPTDKLLVKYNLKEFSGVVKSVRIGDLCNLEAELNINGPFFISCGVYLILEKLKYIAYRNLFKTVSTMIGSHMISISAFSDALKFVGVSDIDIDETECILANLIFENKIKGYLAHQQQKLVMSKTNAFPSIS 1269
            NGE+++K     D H Q+P + I     + K  +  +   + E++  HL+VL +++  +DL  A   Q  +I++F+ ++ ++ KD+NWFLP+   L  DLR L+   +  +    +  S+A    +  A  +   +R CVSD  +   T+KK+ M+ + NQLF+I+F I++LNL K LI AI+N G +   F +  +V YNY++GRK MFD +   A +SL +AF NC  D + NKR ILIYLIPVKM LG+ PT +LL +Y L EF  VV  V+ G+L  L+  L  N  FFI CG++L+LEKL+ I +R LFK VS ++G+  I + AF  AL+FVGV+D+D+DE ECI+ANLI   KIKGYL+HQ QKLV+SK NAFP++S
Sbjct:   25 NGEKISKFVSTYDEHAQEPFMHIEAYGSRSKRCRVSEDEVFDEIVCLHLHVLYNIHVAQDLITAQSTQIQIIQLFNKEILQKRKDENWFLPIFYRLCTDLRWLSKGAEACVSGDDEGDSNANSFFESAAKAITECYRTCVSDVHAEEGTTKKVAMLNMTNQLFQIYFQINKLNLLKPLIRAIDNCGSLYHDFLMSDKVAYNYFLGRKAMFDADLNLAEKSLLYAFRNCPADSMSNKRKILIYLIPVKMFLGHMPTSQLLHEYRLDEFQDVVAGVKDGNLAQLDGALAANEAFFIKCGIFLMLEKLRMITFRTLFKKVSQIVGTAQIPLDAFQTALRFVGVTDVDMDELECIIANLIASKKIKGYLSHQHQKLVISKMNAFPTLS 408
[Close]
BLAST of PCI domain-containing protein 2 vs. Ensembl Fly
Match: PCID2 (gene:FBgn0036184 transcript:FBtr0076102)

HSP 1 Score: 320.087 bits (819), Expect = 6.328e-106
Identity = 169/399 (42.36%), Postives = 248/399 (62.16%), Query Frame = 1 
Query:   88 TIETFISMVAKNVKALNGEELAKLFDLNDRHIQDPTLIPFIPEKMKMGKQFVPWREMIVSHLNVLTHLNNKDLKGALE---EQFNLIEIFSDLFEQIKDDNWFLPVMTVLTVDLRCLAHAMDYGIDSQVKHHS--SAGENMKRVADCLMRLFRKCVSDSRSNVETSKKMGMMALCNQLFKIFFTISQLNLCKSLILAIENLGIIDKFSICQQVTYNYYVGRKCMFDDNFQKANESLTFAFENCHRDYVKNKRLILIYLIPVKMLLGNFPTDKLLVKYNLKEFSGVVKSVRIGDLCNLEAELNINGPFFISCGVYLILEKLKYIAYRNLFKTVSTMIGSHMISISAFSDALKFVGVSDIDIDETECILANLIFENKIKGYLAHQQQKLVMSKTNAFPSIS 1269
            T+  ++S V    + L+GE LA    L D H+Q+  L    PEK+       P  E++ +HL VL HL  ++  G +E   +Q         L +Q+KD+NW LP+M  + +DLR LA A +       KH    + G  +++ ADC+M  FR C +D R++ E +K++GMM L NQLFKI+F I++L+LCK LI AI+N    D F + +Q+TY Y+VGR+ MFD N+Q A + L++AF NC   +  NKRLILIYL+PVKMLLG  P+  LL +Y+L  F  +  +++ G++   +  +       I  G+YL++EKLK++ YRNLFK V  +  SH + +  F  AL FVG++D+ +DET CI+ANLI++ KIKGY++H   KLV+SK N FPS+S
Sbjct:    4 TVNNYLSGVLHAAQDLDGESLATYLSLRDVHVQNHNLYIAQPEKLVDRFLKPPLDEVVSAHLKVLYHLA-QEPPGYMEAYTQQSAACGAVVRLLQQLKDENWCLPLMYRVCLDLRYLAQACE-------KHCQGFTPGHVLEKAADCIMACFRVCAADGRASEEDTKRLGMMNLVNQLFKIYFRINKLHLCKPLIRAIDNCIFKDSFPLPEQITYKYFVGRRAMFDSNYQAAVQYLSYAFSNCPDRFASNKRLILIYLVPVKMLLGYLPSKSLLQRYDLLLFLDLAMAMKAGNVNRFDEIVRDQELVLIRSGIYLLVEKLKFLVYRNLFKKVFVIRKSHQLDMGDFLSALHFVGLTDVSLDETHCIVANLIYDGKIKGYISHAHNKLVVSKQNPFPSVS 394
[Close]
BLAST of PCI domain-containing protein 2 vs. Ensembl Zebrafish
Match: pcid2 (PCI domain containing 2 [Source:NCBI gene;Acc:492509])

HSP 1 Score: 335.495 bits (859), Expect = 1.175e-111
Identity = 173/396 (43.69%), Postives = 259/396 (65.40%), Query Frame = 1 
Query:   82 QMTIETFISMVAKNVKALNGEELAKLFDLNDRHIQDPTLIPFIPEKMKMGKQFVPWREMIVSHLNVLTHLNNKDLKGALEEQFNLIEIFSDLFEQIKDDNWFLPVMTVLTVDLRCLAHAMDYGIDSQVKHHSSAGENMKRVADCLMRLFRKCVSDSRSNVETSKKMGMMALCNQLFKIFFTISQLNLCKSLILAIENLGIIDKFSICQQVTYNYYVGRKCMFDDNFQKANESLTFAFENCHRDYVKNKRLILIYLIPVKMLLGNFPTDKLLVKYNLKEFSGVVKSVRIGDLCNLEAELNINGPFFISCGVYLILEKLKYIAYRNLFKTVSTMIGSHMISISAFSDALKFVGVSDIDIDETECILANLIFENKIKGYLAHQQQKLVMSKTNAFPSIS 1269
             +T+  ++  V + + + +G   A++      H+ +P L    PE+        P+ EM+ +HL     ++N D   A + Q  +++ F   F+  K++NW LP+M  +T+DLR  A+  +  +  Q K     G+ +++ A+ LM  FR C SD+R+ ++ SKK GM+ L NQLFKI+F I++L+LCK LI AI++  + D++++ Q+VTY YYVGRK MFD +F+ A E L+F+F +CHR   +NKRLILIYL+PVKMLLG+ PT +LL KY+L +F+ V K+V  G+L  L A L  +  FFI CG++LILEKLK I YRNLFK V  ++ +H + ++AF  +L+ + V D+DIDE +CILANLI+   IKGY++HQ QKLV+SK N FP +S
Sbjct:    3 HITLNQYLQQVLEAIDSRDGSFCAEMLSFKHPHVANPRLQLSSPEEKCQQLLEPPYDEMVAAHLRCTFAVSNHDFVEAYKCQTVVVQSFLKAFQAHKEENWALPIMFAVTLDLRIFANNAEQQL--QQKGKGKVGDMLEKAAEQLMSCFRVCASDNRAGIDDSKKWGMLFLINQLFKIYFKINKLHLCKPLIRAIDSSNLKDEYTMAQRVTYKYYVGRKAMFDSDFKPAEECLSFSFTHCHRSCQRNKRLILIYLLPVKMLLGHMPTHQLLKKYDLMQFADVTKAVSEGNLLLLNAALVKHETFFIRCGIFLILEKLKIITYRNLFKKVYHLLRTHQLPLAAFLVSLQMMKVEDVDIDEVQCILANLIYMGHIKGYISHQHQKLVVSKQNPFPPLS 396
[Close]
BLAST of PCI domain-containing protein 2 vs. Ensembl Zebrafish
Match: pcid2 (PCI domain containing 2 [Source:NCBI gene;Acc:492509])

HSP 1 Score: 335.495 bits (859), Expect = 1.175e-111
Identity = 173/396 (43.69%), Postives = 259/396 (65.40%), Query Frame = 1 
Query:   82 QMTIETFISMVAKNVKALNGEELAKLFDLNDRHIQDPTLIPFIPEKMKMGKQFVPWREMIVSHLNVLTHLNNKDLKGALEEQFNLIEIFSDLFEQIKDDNWFLPVMTVLTVDLRCLAHAMDYGIDSQVKHHSSAGENMKRVADCLMRLFRKCVSDSRSNVETSKKMGMMALCNQLFKIFFTISQLNLCKSLILAIENLGIIDKFSICQQVTYNYYVGRKCMFDDNFQKANESLTFAFENCHRDYVKNKRLILIYLIPVKMLLGNFPTDKLLVKYNLKEFSGVVKSVRIGDLCNLEAELNINGPFFISCGVYLILEKLKYIAYRNLFKTVSTMIGSHMISISAFSDALKFVGVSDIDIDETECILANLIFENKIKGYLAHQQQKLVMSKTNAFPSIS 1269
             +T+  ++  V + + + +G   A++      H+ +P L    PE+        P+ EM+ +HL     ++N D   A + Q  +++ F   F+  K++NW LP+M  +T+DLR  A+  +  +  Q K     G+ +++ A+ LM  FR C SD+R+ ++ SKK GM+ L NQLFKI+F I++L+LCK LI AI++  + D++++ Q+VTY YYVGRK MFD +F+ A E L+F+F +CHR   +NKRLILIYL+PVKMLLG+ PT +LL KY+L +F+ V K+V  G+L  L A L  +  FFI CG++LILEKLK I YRNLFK V  ++ +H + ++AF  +L+ + V D+DIDE +CILANLI+   IKGY++HQ QKLV+SK N FP +S
Sbjct:    3 HITLNQYLQQVLEAIDSRDGSFCAEMLSFKHPHVANPRLQLSSPEEKCQQLLEPPYDEMVAAHLRCTFAVSNHDFVEAYKCQTVVVQSFLKAFQAHKEENWALPIMFAVTLDLRIFANNAEQQL--QQKGKGKVGDMLEKAAEQLMSCFRVCASDNRAGIDDSKKWGMLFLINQLFKIYFKINKLHLCKPLIRAIDSSNLKDEYTMAQRVTYKYYVGRKAMFDSDFKPAEECLSFSFTHCHRSCQRNKRLILIYLLPVKMLLGHMPTHQLLKKYDLMQFADVTKAVSEGNLLLLNAALVKHETFFIRCGIFLILEKLKIITYRNLFKKVYHLLRTHQLPLAAFLVSLQMMKVEDVDIDEVQCILANLIYMGHIKGYISHQHQKLVVSKQNPFPPLS 396
[Close]
BLAST of PCI domain-containing protein 2 vs. Ensembl Xenopus
Match: rnf138 (ring finger protein 138 [Source:Xenbase;Acc:XB-GENE-1001373])

HSP 1 Score: 345.895 bits (886), Expect = 1.076e-115
Identity = 178/396 (44.95%), Postives = 257/396 (64.90%), Query Frame = 1 
Query:   82 QMTIETFISMVAKNVKALNGEELAKLFDLNDRHIQDPTLIPFIPEKMKMGKQFVPWREMIVSHLNVLTHLNNKDLKGALEEQFNLIEIFSDLFEQIKDDNWFLPVMTVLTVDLRCLAHAMDYGIDSQVKHHSSAGENMKRVADCLMRLFRKCVSDSRSNVETSKKMGMMALCNQLFKIFFTISQLNLCKSLILAIENLGIIDKFSICQQVTYNYYVGRKCMFDDNFQKANESLTFAFENCHRDYVKNKRLILIYLIPVKMLLGNFPTDKLLVKYNLKEFSGVVKSVRIGDLCNLEAELNINGPFFISCGVYLILEKLKYIAYRNLFKTVSTMIGSHMISISAFSDALKFVGVSDIDIDETECILANLIFENKIKGYLAHQQQKLVMSKTNAFPSIS 1269
             +TI  ++  V + + + NG   A L      H+ +  L    PE+        P+ EM  +HL  +  ++N D   A + Q  +++ F   F+  K++NW LP+M  +T+DLR  A+  D  +  + K     G+ +++ A+ LM  FR C SD+R++ E SKK GM+ L NQLFKI+F IS+L+LCK LI AI++    +++++ Q+VTY YYVGRK MFD +F+KA E L+FAFE+CHR   KNKR+ILIYL+PVKMLLG+ P  +LL KY+L +F+ V K+V  G+L  L   L+ +  FFI CG++LILE LK I+YRNLFK V  ++ +H +S+ AF  ALKF+ V DID+ E +CI+ANLI+   IKGY++HQ QKLV+SK N FP +S
Sbjct:    3 HITINQYLQQVQEAIDSKNGYNCADLVSFRHPHVANARLQLSSPEEKCQQVLEPPYDEMFAAHLRCINAVSNHDFVEAYKYQTLVVQSFLKSFQAHKEENWALPIMYSITLDLRIFANNADQQLVKKGK--GKVGDMLEKAAELLMSCFRVCASDTRASFEDSKKWGMLFLVNQLFKIYFKISKLHLCKPLIRAIDSSNFKEEYTMAQRVTYKYYVGRKSMFDSDFKKAEEYLSFAFEHCHRSSQKNKRMILIYLLPVKMLLGHMPAIQLLKKYDLMQFAEVTKAVSEGNLLLLTEALSKHETFFIRCGIFLILENLKIISYRNLFKKVYLLLKTHQLSLDAFLVALKFMEVEDIDLAEVQCIIANLIYMGHIKGYISHQHQKLVVSKQNPFPPLS 396
[Close]
BLAST of PCI domain-containing protein 2 vs. Ensembl Xenopus
Match: rnf138 (ring finger protein 138 [Source:Xenbase;Acc:XB-GENE-1001373])

HSP 1 Score: 324.709 bits (831), Expect = 1.467e-107
Identity = 173/396 (43.69%), Postives = 248/396 (62.63%), Query Frame = 1 
Query:   82 QMTIETFISMVAKNVKALNGEELAKLFDLNDRHIQDPTLIPFIPEKMKMGKQFVPWREMIVSHLNVLTHLNNKDLKGALEEQFNLIEIFSDLFEQIKDDNWFLPVMTVLTVDLRCLAHAMDYGIDSQVKHHSSAGENMKRVADCLMRLFRKCVSDSRSNVETSKKMGMMALCNQLFKIFFTISQLNLCKSLILAIENLGIIDKFSICQQVTYNYYVGRKCMFDDNFQKANESLTFAFENCHRDYVKNKRLILIYLIPVKMLLGNFPTDKLLVKYNLKEFSGVVKSVRIGDLCNLEAELNINGPFFISCGVYLILEKLKYIAYRNLFKTVSTMIGSHMISISAFSDALKFVGVSDIDIDETECILANLIFENKIKGYLAHQQQKLVMSKTNAFPSIS 1269
             +TI  ++  V + + + NG   A L      H+ +  L    PE+        P+ EM  +HL  +  ++N D   A + Q  ++                LP+M  +T+DLR  A+  D  +  + K     G+ +++ A+ LM  FR C SD+R++ E SKK GM+ L NQLFKI+F IS+L+LCK LI AI++    +++++ Q+VTY YYVGRK MFD +F+KA E L+FAFE+CHR   KNKR+ILIYL+PVKMLLG+ P  +LL KY+L +F+ V K+V  G+L  L   L+ +  FFI CG++LILE LK I+YRNLFK V  ++ +H +S+ AF  ALKF+ V DID+ E +CI+ANLI+   IKGY++HQ QKLV+SK N FP +S
Sbjct:    3 HITINQYLQQVQEAIDSKNGYNCADLVSFRHPHVANARLQLSSPEEKCQQVLEPPYDEMFAAHLRCINAVSNHDFVEAYKYQTLVVA---------------LPIMYSITLDLRIFANNADQQLVKKGK--GKVGDMLEKAAELLMSCFRVCASDTRASFEDSKKWGMLFLVNQLFKIYFKISKLHLCKPLIRAIDSSNFKEEYTMAQRVTYKYYVGRKSMFDSDFKKAEEYLSFAFEHCHRSSQKNKRMILIYLLPVKMLLGHMPAIQLLKKYDLMQFAEVTKAVSEGNLLLLTEALSKHETFFIRCGIFLILENLKIISYRNLFKKVYLLLKTHQLSLDAFLVALKFMEVEDIDLAEVQCIIANLIYMGHIKGYISHQHQKLVVSKQNPFPPLS 381
[Close]
BLAST of PCI domain-containing protein 2 vs. Ensembl Xenopus
Match: rnf138 (ring finger protein 138 [Source:Xenbase;Acc:XB-GENE-1001373])

HSP 1 Score: 320.087 bits (819), Expect = 8.720e-106
Identity = 175/395 (44.30%), Postives = 247/395 (62.53%), Query Frame = 1 
Query:  103 ISMVAKN------VKALNGEELAKLFDLNDRHIQDPTLIPFIPEKMKMGKQFVPWREMIVSHLNVLTHLNNKDLKGALEEQFNLIEIFSDLFEQIKDDNWFLPVMTVLTVDLRCLAHAMDYGIDSQVKHHSSAGENMKRVADCLMRLFRKCVSDSRSNVETSKKMGMMALCNQLFKIFFTISQLNLCKSLILAIENLGIIDKFSICQQVTYNYYVGRKCMFDDNFQKANESLTFAFENCHRDYVKNKRLILIYLIPVKMLLGNFPTDKLLVKYNLKEFSGVVKSVRIGDLCNLEAELNINGPFFISCGVYLILEKLKYIAYRNLFKTVSTMIGSHMISISAFSDALKFVGVSDIDIDETECILANLIFENKIKGYLAHQQQKLVMSKTNAFPSIS 1269
            IS VAK+      + + NG   A L      H+ +  L    PE+        P+ EM  +HL  +  ++N D   A + Q  ++                LP+M  +T+DLR  A+  D  +  + K     G+ +++ A+ LM  FR C SD+R++ E SKK GM+ L NQLFKI+F IS+L+LCK LI AI++    +++++ Q+VTY YYVGRK MFD +F+KA E L+FAFE+CHR   KNKR+ILIYL+PVKMLLG+ P  +LL KY+L +F+ V K+V  G+L  L   L+ +  FFI CG++LILE LK I+YRNLFK V  ++ +H +S+ AF  ALKF+ V DID+ E +CI+ANLI+   IKGY++HQ QKLV+SK N FP +S
Sbjct:    3 ISTVAKHLLVQEAIDSKNGYNCADLVSFRHPHVANARLQLSSPEEKCQQVLEPPYDEMFAAHLRCINAVSNHDFVEAYKYQTLVVA---------------LPIMYSITLDLRIFANNADQQLVKKGK--GKVGDMLEKAAELLMSCFRVCASDTRASFEDSKKWGMLFLVNQLFKIYFKISKLHLCKPLIRAIDSSNFKEEYTMAQRVTYKYYVGRKSMFDSDFKKAEEYLSFAFEHCHRSSQKNKRMILIYLLPVKMLLGHMPAIQLLKKYDLMQFAEVTKAVSEGNLLLLTEALSKHETFFIRCGIFLILENLKIISYRNLFKKVYLLLKTHQLSLDAFLVALKFMEVEDIDLAEVQCIIANLIYMGHIKGYISHQHQKLVVSKQNPFPPLS 380
[Close]
BLAST of PCI domain-containing protein 2 vs. Ensembl Xenopus
Match: rnf138 (ring finger protein 138 [Source:Xenbase;Acc:XB-GENE-1001373])

HSP 1 Score: 314.694 bits (805), Expect = 3.175e-104
Identity = 162/342 (47.37%), Postives = 228/342 (66.67%), Query Frame = 1 
Query:  244 PWREMIVSHLNVLTHLNNKDLKGALEEQFNLIEIFSDLFEQIKDDNWFLPVMTVLTVDLRCLAHAMDYGIDSQVKHHSSAGENMKRVADCLMRLFRKCVSDSRSNVETSKKMGMMALCNQLFKIFFTISQLNLCKSLILAIENLGIIDKFSICQQVTYNYYVGRKCMFDDNFQKANESLTFAFENCHRDYVKNKRLILIYLIPVKMLLGNFPTDKLLVKYNLKEFSGVVKSVRIGDLCNLEAELNINGPFFISCGVYLILEKLKYIAYRNLFKTVSTMIGSHMISISAFSDALKFVGVSDIDIDETECILANLIFENKIKGYLAHQQQKLVMSKTNAFPSIS 1269
            P+ EM  +HL  +  ++N D   A + Q  ++                LP+M  +T+DLR  A+  D  +  + K     G+ +++ A+ LM  FR C SD+R++ E SKK GM+ L NQLFKI+F IS+L+LCK LI AI++    +++++ Q+VTY YYVGRK MFD +F+KA E L+FAFE+CHR   KNKR+ILIYL+PVKMLLG+ P  +LL KY+L +F+ V K+V  G+L  L   L+ +  FFI CG++LILE LK I+YRNLFK V  ++ +H +S+ AF  ALKF+ V DID+ E +CI+ANLI+   IKGY++HQ QKLV+SK N FP +S
Sbjct:   19 PYDEMFAAHLRCINAVSNHDFVEAYKYQTLVVA---------------LPIMYSITLDLRIFANNADQQLVKKGK--GKVGDMLEKAAELLMSCFRVCASDTRASFEDSKKWGMLFLVNQLFKIYFKISKLHLCKPLIRAIDSSNFKEEYTMAQRVTYKYYVGRKSMFDSDFKKAEEYLSFAFEHCHRSSQKNKRMILIYLLPVKMLLGHMPAIQLLKKYDLMQFAEVTKAVSEGNLLLLTEALSKHETFFIRCGIFLILENLKIISYRNLFKKVYLLLKTHQLSLDAFLVALKFMEVEDIDLAEVQCIIANLIYMGHIKGYISHQHQKLVVSKQNPFPPLS 343
[Close]
BLAST of PCI domain-containing protein 2 vs. Ensembl Xenopus
Match: rnf138 (ring finger protein 138 [Source:Xenbase;Acc:XB-GENE-1001373])

HSP 1 Score: 308.145 bits (788), Expect = 2.865e-101
Identity = 168/396 (42.42%), Postives = 237/396 (59.85%), Query Frame = 1 
Query:   82 QMTIETFISMVAKNVKALNGEELAKLFDLNDRHIQDPTLIPFIPEKMKMGKQFVPWREMIVSHLNVLTHLNNKDLKGALEEQFNLIEIFSDLFEQIKDDNWFLPVMTVLTVDLRCLAHAMDYGIDSQVKHHSSAGENMKRVADCLMRLFRKCVSDSRSNVETSKKMGMMALCNQLFKIFFTISQLNLCKSLILAIENLGIIDKFSICQQVTYNYYVGRKCMFDDNFQKANESLTFAFENCHRDYVKNKRLILIYLIPVKMLLGNFPTDKLLVKYNLKEFSGVVKSVRIGDLCNLEAELNINGPFFISCGVYLILEKLKYIAYRNLFKTVSTMIGSHMISISAFSDALKFVGVSDIDIDETECILANLIFENKIKGYLAHQQQKLVMSKTNAFPSIS 1269
             +TI  ++  V + + + NG   A L      H+ +  L    PE+        P+ EM  +HL  +  ++N D   A + Q     +F      IK D   +                         K     G+ +++ A+ LM  FR C SD+R++ E SKK GM+ L NQLFKI+F IS+L+LCK LI AI++    +++++ Q+VTY YYVGRK MFD +F+KA E L+FAFE+CHR   KNKR+ILIYL+PVKMLLG+ P  +LL KY+L +F+ V K+V  G+L  L   L+ +  FFI CG++LILE LK I+YRNLFK V  ++ +H +S+ AF  ALKF+ V DID+ E +CI+ANLI+   IKGY++HQ QKLV+SK N FP +S
Sbjct:    3 HITINQYLQQVQEAIDSKNGYNCADLVSFRHPHVANARLQLSSPEEKCQQVLEPPYDEMFAAHLRCINAVSNHDFVEAYKYQ---TLVFYMAVAPIKADQQLVK------------------------KGKGKVGDMLEKAAELLMSCFRVCASDTRASFEDSKKWGMLFLVNQLFKIYFKISKLHLCKPLIRAIDSSNFKEEYTMAQRVTYKYYVGRKSMFDSDFKKAEEYLSFAFEHCHRSSQKNKRMILIYLLPVKMLLGHMPAIQLLKKYDLMQFAEVTKAVSEGNLLLLTEALSKHETFFIRCGIFLILENLKIISYRNLFKKVYLLLKTHQLSLDAFLVALKFMEVEDIDLAEVQCIIANLIYMGHIKGYISHQHQKLVVSKQNPFPPLS 371
[Close]
BLAST of PCI domain-containing protein 2 vs. Ensembl Mouse
Match: Pcid2 (PCI domain containing 2 [Source:MGI Symbol;Acc:MGI:2443003])

HSP 1 Score: 350.517 bits (898), Expect = 1.291e-117
Identity = 183/396 (46.21%), Postives = 256/396 (64.65%), Query Frame = 1 
Query:   82 QMTIETFISMVAKNVKALNGEELAKLFDLNDRHIQDPTLIPFIPEKMKMGKQFVPWREMIVSHLNVLTHLNNKDLKGALEEQFNLIEIFSDLFEQIKDDNWFLPVMTVLTVDLRCLAHAMDYGIDSQVKHHSSAGENMKRVADCLMRLFRKCVSDSRSNVETSKKMGMMALCNQLFKIFFTISQLNLCKSLILAIENLGIIDKFSICQQVTYNYYVGRKCMFDDNFQKANESLTFAFENCHRDYVKNKRLILIYLIPVKMLLGNFPTDKLLVKYNLKEFSGVVKSVRIGDLCNLEAELNINGPFFISCGVYLILEKLKYIAYRNLFKTVSTMIGSHMISISAFSDALKFVGVSDIDIDETECILANLIFENKIKGYLAHQQQKLVMSKTNAFPSIS 1269
             +TI  ++  V + +   +G   A+L      H+ +P L    PE+        P+ EM  +HL     + N D   A + Q  +++ F   F+  K++NW LPVM  + +DLR  A+  D  +  + K  S  G+ +++ A+ LM  FR C SD+R+ +E SKK GM+ L NQLFKI+F I++L+LCK LI AI++  + D +S  Q++TY YYVGRK MFD +F++A E L+FAFE+CHR   KNKR+ILIYL+PVKMLLG+ PT +LL KY+L +FS V K+V  G+L  L   L  +  FFI CG++LILEKLK I YRNLFK V  ++ +H +S+ AF  ALKF+ V D+DIDE +CILANLI+   IKGY++HQ QKLV+SK N FP +S
Sbjct:    3 HITINQYLQQVYEAIDTRDGASCAELVSFKHPHVANPRLQMASPEEKCQQVLEPPYDEMFAAHLRCTYAVGNHDFIEAYKCQTVIVQSFLRAFQAHKEENWALPVMYAVALDLRIFANNADQQLVKKGK--SKVGDMLEKAAELLMSCFRVCASDTRAGIEDSKKWGMLFLVNQLFKIYFKINKLHLCKPLIRAIDSSNLKDDYSTAQRITYKYYVGRKAMFDSDFKQAEEYLSFAFEHCHRSSQKNKRMILIYLLPVKMLLGHMPTIELLRKYHLMQFSEVTKAVSEGNLLLLNEALAKHETFFIRCGIFLILEKLKIITYRNLFKKVYLLLKTHQLSLDAFLVALKFMHVEDVDIDEVQCILANLIYMGHIKGYISHQHQKLVVSKQNPFPPLS 396
[Close]
BLAST of PCI domain-containing protein 2 vs. Ensembl Mouse
Match: Pcid2 (PCI domain containing 2 [Source:MGI Symbol;Acc:MGI:2443003])

HSP 1 Score: 60.8474 bits (146), Expect = 6.003e-11
Identity = 33/117 (28.21%), Postives = 55/117 (47.01%), Query Frame = 1 
Query:   82 QMTIETFISMVAKNVKALNGEELAKLFDLNDRHIQDPTLIPFIPEKMKMGKQFVPWREMIVSHLNVLTHLNNKDLKGALEEQFNLIEIFSDLFEQIKDDNWFLPVMTVLTVDLRCLA 432
             +TI  ++  V + +   +G   A+L      H+ +P L    PE+        P+ EM  +HL     + N D   A + Q  +++ F   F+  K++NW LPVM  + +DLR  A
Sbjct:    3 HITINQYLQQVYEAIDTRDGASCAELVSFKHPHVANPRLQMASPEEKCQQVLEPPYDEMFAAHLRCTYAVGNHDFIEAYKCQTVIVQSFLRAFQAHKEENWALPVMYAVALDLRIFA 119
[Close]
BLAST of PCI domain-containing protein 2 vs. UniProt/SwissProt
Match: sp|Q5JVF3|PCID2_HUMAN (PCI domain-containing protein 2 OS=Homo sapiens OX=9606 GN=PCID2 PE=1 SV=2)

HSP 1 Score: 355.91 bits (912), Expect = 7.129e-119
Identity = 181/396 (45.71%), Postives = 257/396 (64.90%), Query Frame = 1 
Query:   82 QMTIETFISMVAKNVKALNGEELAKLFDLNDRHIQDPTLIPFIPEKMKMGKQFVPWREMIVSHLNVLTHLNNKDLKGALEEQFNLIEIFSDLFEQIKDDNWFLPVMTVLTVDLRCLAHAMDYGIDSQVKHHSSAGENMKRVADCLMRLFRKCVSDSRSNVETSKKMGMMALCNQLFKIFFTISQLNLCKSLILAIENLGIIDKFSICQQVTYNYYVGRKCMFDDNFQKANESLTFAFENCHRDYVKNKRLILIYLIPVKMLLGNFPTDKLLVKYNLKEFSGVVKSVRIGDLCNLEAELNINGPFFISCGVYLILEKLKYIAYRNLFKTVSTMIGSHMISISAFSDALKFVGVSDIDIDETECILANLIFENKIKGYLAHQQQKLVMSKTNAFPSIS 1269
             +TI  ++  V + + + +G   A+L      H+ +P L    PE+        P+ EM  +HL     + N D   A + Q  +++ F   F+  K++NW LPVM  + +DLR  A+  D  +  + K  S  G+ +++ A+ LM  FR C SD+R+ +E SKK GM+ L NQLFKI+F I++L+LCK LI AI++  + D +S  Q+VTY YYVGRK MFD +F++A E L+FAFE+CHR   KNKR+ILIYL+PVKMLLG+ PT +LL KY+L +F+ V ++V  G+L  L   L  +  FFI CG++LILEKLK I YRNLFK V  ++ +H +S+ AF  ALKF+ V D+DIDE +CILANLI+   +KGY++HQ QKLV+SK N FP +S
Sbjct:    3 HITINQYLQQVYEAIDSRDGASCAELVSFKHPHVANPRLQMASPEEKCQQVLEPPYDEMFAAHLRCTYAVGNHDFIEAYKCQTVIVQSFLRAFQAHKEENWALPVMYAVALDLRVFANNADQQLVKKGK--SKVGDMLEKAAELLMSCFRVCASDTRAGIEDSKKWGMLFLVNQLFKIYFKINKLHLCKPLIRAIDSSNLKDDYSTAQRVTYKYYVGRKAMFDSDFKQAEEYLSFAFEHCHRSSQKNKRMILIYLLPVKMLLGHMPTVELLKKYHLMQFAEVTRAVSEGNLLLLHEALAKHEAFFIRCGIFLILEKLKIITYRNLFKKVYLLLKTHQLSLDAFLVALKFMQVEDVDIDEVQCILANLIYMGHVKGYISHQHQKLVVSKQNPFPPLS 396
[Close]
BLAST of PCI domain-containing protein 2 vs. UniProt/SwissProt
Match: sp|Q8BFV2|PCID2_MOUSE (PCI domain-containing protein 2 OS=Mus musculus OX=10090 GN=Pcid2 PE=1 SV=1)

HSP 1 Score: 350.517 bits (898), Expect = 9.031e-117
Identity = 183/396 (46.21%), Postives = 256/396 (64.65%), Query Frame = 1 
Query:   82 QMTIETFISMVAKNVKALNGEELAKLFDLNDRHIQDPTLIPFIPEKMKMGKQFVPWREMIVSHLNVLTHLNNKDLKGALEEQFNLIEIFSDLFEQIKDDNWFLPVMTVLTVDLRCLAHAMDYGIDSQVKHHSSAGENMKRVADCLMRLFRKCVSDSRSNVETSKKMGMMALCNQLFKIFFTISQLNLCKSLILAIENLGIIDKFSICQQVTYNYYVGRKCMFDDNFQKANESLTFAFENCHRDYVKNKRLILIYLIPVKMLLGNFPTDKLLVKYNLKEFSGVVKSVRIGDLCNLEAELNINGPFFISCGVYLILEKLKYIAYRNLFKTVSTMIGSHMISISAFSDALKFVGVSDIDIDETECILANLIFENKIKGYLAHQQQKLVMSKTNAFPSIS 1269
             +TI  ++  V + +   +G   A+L      H+ +P L    PE+        P+ EM  +HL     + N D   A + Q  +++ F   F+  K++NW LPVM  + +DLR  A+  D  +  + K  S  G+ +++ A+ LM  FR C SD+R+ +E SKK GM+ L NQLFKI+F I++L+LCK LI AI++  + D +S  Q++TY YYVGRK MFD +F++A E L+FAFE+CHR   KNKR+ILIYL+PVKMLLG+ PT +LL KY+L +FS V K+V  G+L  L   L  +  FFI CG++LILEKLK I YRNLFK V  ++ +H +S+ AF  ALKF+ V D+DIDE +CILANLI+   IKGY++HQ QKLV+SK N FP +S
Sbjct:    3 HITINQYLQQVYEAIDTRDGASCAELVSFKHPHVANPRLQMASPEEKCQQVLEPPYDEMFAAHLRCTYAVGNHDFIEAYKCQTVIVQSFLRAFQAHKEENWALPVMYAVALDLRIFANNADQQLVKKGK--SKVGDMLEKAAELLMSCFRVCASDTRAGIEDSKKWGMLFLVNQLFKIYFKINKLHLCKPLIRAIDSSNLKDDYSTAQRITYKYYVGRKAMFDSDFKQAEEYLSFAFEHCHRSSQKNKRMILIYLLPVKMLLGHMPTIELLRKYHLMQFSEVTKAVSEGNLLLLNEALAKHETFFIRCGIFLILEKLKIITYRNLFKKVYLLLKTHQLSLDAFLVALKFMHVEDVDIDEVQCILANLIYMGHIKGYISHQHQKLVVSKQNPFPPLS 396
[Close]
BLAST of PCI domain-containing protein 2 vs. UniProt/SwissProt
Match: sp|Q5FWP8|PCID2_XENLA (PCI domain-containing protein 2 OS=Xenopus laevis OX=8355 GN=pcid2 PE=2 SV=1)

HSP 1 Score: 347.821 bits (891), Expect = 1.061e-115
Identity = 179/396 (45.20%), Postives = 256/396 (64.65%), Query Frame = 1 
Query:   82 QMTIETFISMVAKNVKALNGEELAKLFDLNDRHIQDPTLIPFIPEKMKMGKQFVPWREMIVSHLNVLTHLNNKDLKGALEEQFNLIEIFSDLFEQIKDDNWFLPVMTVLTVDLRCLAHAMDYGIDSQVKHHSSAGENMKRVADCLMRLFRKCVSDSRSNVETSKKMGMMALCNQLFKIFFTISQLNLCKSLILAIENLGIIDKFSICQQVTYNYYVGRKCMFDDNFQKANESLTFAFENCHRDYVKNKRLILIYLIPVKMLLGNFPTDKLLVKYNLKEFSGVVKSVRIGDLCNLEAELNINGPFFISCGVYLILEKLKYIAYRNLFKTVSTMIGSHMISISAFSDALKFVGVSDIDIDETECILANLIFENKIKGYLAHQQQKLVMSKTNAFPSIS 1269
             +TI  ++  V + + + +G   A L      H+ +  L    PE+        P+ EM  +HL  +   +N D   A + Q  +++ F   F+  K++NW LP+M  +T+DLR  A+  D  +  + K     G+ +++ A+ LM  FR C SD+R+  E SKK GM+ L NQLFKI+F IS+L+LCK LI AI++    +++++ Q+VT+ YYVGRK MFD +F+KA E L+FAFE+CHR   KNKR+ILIYL+PVKMLLG+ PT  LL KY+L +F+ V K+V  G+L  L   L  +  FFI CG++LILEKLK I+YRNLFK V  ++ +H +S+ AF  ALKF+ V D+DIDE +CI+ANLI+   IKGY++HQ QKLV+SK N FP +S
Sbjct:    3 HITINQYLQQVQEAIDSKDGFNCADLVSFKHPHVANARLQLLSPEEKCQQVLEPPYDEMFAAHLRCINAASNHDFVEAYKYQTLVVQSFLKSFQAHKEENWALPIMYSITLDLRIFANNADQQLVKKGK--GKVGDMLEKAAEILMSCFRVCASDTRAAFEDSKKWGMLFLVNQLFKIYFKISKLHLCKPLIRAIDSSNFKEEYTMAQRVTFKYYVGRKSMFDSDFKKAEEYLSFAFEHCHRSSQKNKRMILIYLLPVKMLLGHMPTIHLLKKYDLMQFAEVTKAVSEGNLLLLTEALTKHETFFIRCGIFLILEKLKIISYRNLFKKVYLLLKTHQLSLDAFLVALKFMEVGDVDIDEVQCIIANLIYMGHIKGYISHQHQKLVVSKQNPFPPLS 396
[Close]
BLAST of PCI domain-containing protein 2 vs. UniProt/SwissProt
Match: sp|Q2TBN6|PCID2_BOVIN (PCI domain-containing protein 2 OS=Bos taurus OX=9913 GN=PCID2 PE=2 SV=1)

HSP 1 Score: 343.199 bits (879), Expect = 8.659e-114
Identity = 181/405 (44.69%), Postives = 258/405 (63.70%), Query Frame = 1 
Query:   82 QMTIETFISMVAKNVKALNGEELAKLFDLNDRHIQDPTLIPFIPEKMKMGKQFVPWREMIVSHLNVLTHLNNKDLKGALEEQFNLIEIFSDLFEQIKDDNWFLPVMTVLTVDLRCLAHAMDYGIDSQVKHHSSAGENMKRVADCLMRLFRKCVSDSRSNVETSKKMGMMALCNQLFKIFFTISQLNLCKSLILAIENLGIIDKFSICQQVTYNYYVGRKCMFDDNFQKANESLTFAFENCHRDYVKNKRLILIYLIPVKMLLGNFPTDKLLVKYNLKEFSGVVKSVRIGDLCNLEAELNINGPFFISCGVYLILEKLKYIAYRNLFKTVST---------MIGSHMISISAFSDALKFVGVSDIDIDETECILANLIFENKIKGYLAHQQQKLVMSKTNAFPSIS 1269
             +TI  ++  V + +   +G  LA+L      H+ +P L    PE+        P+ EM  +HL     + N D   A + Q  +++ F   F+  K++NW LPVM  + +DLR  A+  D  +  + K  S  G+ +++ A+ LM  FR C SD+R+ +E SKK GM+ L NQLFKI+F I++L+LCK LI AI++  + D +S  Q+VTY YYVGRK MFD +F++A E L+FAFE+CHR   KNKR++LIYL+PVKMLLG+ PT +LL KY+L +F+ V ++V  G+L  L   L  +  FFI CG++LILEKLK I YRNLFK V++         ++ +H +S+ AF  ALKF+ V D+DI E +CILANLI+   IKGY++HQ QKLV+SK N FP +S
Sbjct:    3 HITINQYLQQVCEAIDTRDGASLAELVSFKHPHVANPRLQMASPEEKCQQVLEPPYDEMFAAHLRCTYAVGNHDFIEAYKCQTVIVQSFLRAFQAHKEENWALPVMYAVALDLRIFANNADQQLVKKGK--SKVGDMLEKAAELLMGCFRVCASDTRAGIEDSKKRGMLFLVNQLFKIYFKINKLHLCKPLIRAIDSSNLKDDYSTAQRVTYRYYVGRKAMFDSDFKQAEEYLSFAFEHCHRSSQKNKRMVLIYLLPVKMLLGHMPTIELLRKYHLMQFAEVTRAVSEGNLLLLNEALAAHETFFIRCGIFLILEKLKIITYRNLFKKVNSLSSASSRYLLLKTHQLSLDAFLVALKFMQVEDVDIAEVQCILANLIYMGHIKGYISHQHQKLVVSKQNPFPPLS 405
[Close]
BLAST of PCI domain-containing protein 2 vs. UniProt/SwissProt
Match: sp|Q5U3P0|PCID2_DANRE (PCI domain-containing protein 2 OS=Danio rerio OX=7955 GN=pcid2 PE=2 SV=1)

HSP 1 Score: 334.339 bits (856), Expect = 1.895e-110
Identity = 172/396 (43.43%), Postives = 258/396 (65.15%), Query Frame = 1 
Query:   82 QMTIETFISMVAKNVKALNGEELAKLFDLNDRHIQDPTLIPFIPEKMKMGKQFVPWREMIVSHLNVLTHLNNKDLKGALEEQFNLIEIFSDLFEQIKDDNWFLPVMTVLTVDLRCLAHAMDYGIDSQVKHHSSAGENMKRVADCLMRLFRKCVSDSRSNVETSKKMGMMALCNQLFKIFFTISQLNLCKSLILAIENLGIIDKFSICQQVTYNYYVGRKCMFDDNFQKANESLTFAFENCHRDYVKNKRLILIYLIPVKMLLGNFPTDKLLVKYNLKEFSGVVKSVRIGDLCNLEAELNINGPFFISCGVYLILEKLKYIAYRNLFKTVSTMIGSHMISISAFSDALKFVGVSDIDIDETECILANLIFENKIKGYLAHQQQKLVMSKTNAFPSIS 1269
             +T+  ++  V + + + +G   A++      H+ +P L    PE+        P+ EM+ +HL     ++N D   A + Q  +++ F   F+  K++NW LP+M  +T+DLR  A+  +  +  Q K     G+ +++ A+ LM  FR C SD+R+ ++ SKK GM+ L NQLFKI+F I++L+LCK LI AI++  + D++++ Q+VTY YYVGRK MFD +F+ A E L+F+F +CHR   +NKRLILIYL+PVKMLLG+ PT +LL KY+L +F+ V ++V  G+L  L A L  +  FFI CG++LILEKLK I YRNLFK V  ++ +H + ++AF  +L+   V D+DIDE +CILANLI+   IKGY++HQ QKLV+SK N FP +S
Sbjct:    3 HITLNQYLQQVLEAIDSRDGSFCAEMMSFKHPHVANPRLQLSSPEEKCQQLLEPPYDEMVAAHLRCTFAVSNHDFVEAYKCQTVVVQSFLKAFQAHKEENWALPIMFAVTLDLRIFANNAEQHL--QQKGKGKVGDMLEKAAEQLMSCFRVCASDNRAGIDDSKKWGMLFLINQLFKIYFKINKLHLCKPLIRAIDSSNLKDEYTMAQRVTYKYYVGRKAMFDSDFKPAEECLSFSFTHCHRSCQRNKRLILIYLLPVKMLLGHMPTHQLLKKYDLMQFADVTRAVSEGNLLLLNAALVKHETFFIRCGIFLILEKLKIITYRNLFKKVYHLLRTHQLPLAAFLVSLQMTKVEDVDIDEVQCILANLIYMGHIKGYISHQHQKLVVSKQNPFPPLS 396
[Close]
BLAST of PCI domain-containing protein 2 vs. TrEMBL
Match: A0A4S2MAW6 (PCI domain-containing protein OS=Opisthorchis felineus OX=147828 GN=CRM22_002678 PE=4 SV=1)

HSP 1 Score: 393.66 bits (1010), Expect = 4.230e-131
Identity = 194/392 (49.49%), Postives = 265/392 (67.60%), Query Frame = 1 
Query:   97 TFISMVAKNVKALNGEELAKLFDLNDRHIQDPTLIPFIPEKMKMGKQFVPWREMIVSHLNVLTHLNNKDLKGALEEQFNLIEIFSDLFEQIKDDNWFLPVMTVLTVDLRCLAHAMDY-GIDSQVKHHSSAGENMKRVADCLMRLFRKCVSDSRSNVETSKKMGMMALCNQLFKIFFTISQLNLCKSLILAIENLGIIDKFSICQQVTYNYYVGRKCMFDDNFQKANESLTFAFENCHRDYVKNKRLILIYLIPVKMLLGNFPTDKLLVKYNLKEFSGVVKSVRIGDLCNLEAELNINGPFFISCGVYLILEKLKYIAYRNLFKTVSTMIGSHMISISAFSDALKFVGVSDIDIDETECILANLIFENKIKGYLAHQQQKLVMSKTNAFPSIS 1269
             ++S  +  + + NG+ELA   +  D H+ +P L    PE M M     PW E   +H+  +  +  +D + A   Q  L++  + +  +IK++NW LPV+    +DLR  AH +D   + ++ +     G +M+  A  ++RLF+ C SDSR+ ++ SKK+GMM L NQLFKI+F I++LNLCK +I AIEN+ I D+FS+ Q+VTY+YYVGRK MFD +F  A++SL+FAFE C      NKRLILIYLIPVKMLLG FP   LLVKYNL EF G+  + + G+L  ++ ELN    FF+SCGVYLILEKLK I YRNLFK V  ++ +H++ I  F+ AL+ +GV DID DETECILANLI+E KIKGYLAHQQQKLV+SK  AFP+++
Sbjct:    8 VYLSECSSLINSRNGKELAHTLECRDPHVYNPRLANPEPESMVMKHVSTPWDEAFSAHMRCVWAMRKQDFEEAYACQVVLVKTVARILIEIKEENWMLPVVLATAIDLRRFAHGLDAKAVSNKNQLGRGHGRHMETAAQLILRLFQICASDSRTQLDDSKKLGMMGLANQLFKIYFQINKLNLCKPMIRAIENMNINDRFSLAQRVTYSYYVGRKAMFDGDFVSADKSLSFAFERCLGSAWHNKRLILIYLIPVKMLLGVFPYPSLLVKYNLNEFLGISDAAKAGNLQKMDMELNKYEEFFLSCGVYLILEKLKLITYRNLFKKVCAIMKTHLMPIEVFTAALRLMGVEDIDQDETECILANLIYEGKIKGYLAHQQQKLVVSKLQAFPALT 399
[Close]
BLAST of PCI domain-containing protein 2 vs. TrEMBL
Match: A0A504YG57 (PCI domain-containing protein 2 OS=Fasciola gigantica OX=46835 GN=FGIG_09633 PE=4 SV=1)

HSP 1 Score: 392.504 bits (1007), Expect = 1.827e-130
Identity = 196/390 (50.26%), Postives = 264/390 (67.69%), Query Frame = 1 
Query:  124 VKALNGEELAKLFDLNDRHIQDPTLIPFIPEKMKMGKQFVPWREMIVSHLNVLTHLNNKDLKGALEEQFNLIEIFSDLFEQIKDDNWFLPVMTVLTVDLRCLAHAMDYGI----DSQVKHHSSA----GENMKRVADCLMRLFRKCVSDSRSNVETSKKMGMMALCNQLFKIFFTISQLNLCKSLILAIENLGIIDKFSICQQVTYNYYVGRKCMFDDNFQKANESLTFAFENCHRDYVKNKRLILIYLIPVKMLLGNFPTDKLLVKYNLKEFSGVVKSVRIGDLCNLEAELNINGPFFISCGVYLILEKLKYIAYRNLFKTVSTMIGSHMISISAFSDALKFVGVSDIDIDETECILANLIFENKIKGYLAHQQQKLVMSKTNAFPSIS 1269
            +K  NG  L+KL   +D H+ +P L    PE M M     PW E+  +H+  +     KD + A   Q  +++    +  ++K++NW LPV+  + +DLR  AH +D       +S     +SA    G  M+  A  +++LF+ C SDSR+ +E SKK+GMM L NQLFKI+F I++LNLCKS+I AI+NLG+ D+FS+ Q+VTY YYVGRK MFD +F  A++SL+FAFE C      NKRLILIYLIPVKMLLG FP   LL KYNL EF G+ ++V+ GDL  +++ELN +  FF+SCGVYLILEKLK I YRNLFK V +++ +H++ I  F+ AL+ +G+ DID DETECILANLI+E KIKGYLAHQQQKLV+SK   FP ++
Sbjct:   17 IKNKNGPALSKLLACSDPHVYNPRLADPEPESMAMKHLQAPWDEIFSAHMRCIWATRKKDFEEAYACQMIVVKTVGRILTELKEENWILPVVLSVAIDLRRFAHGLDSTAAEANNSGAVKSTSANRMHGRRMETAAQSILKLFQICASDSRTQIEDSKKLGMMGLANQLFKIYFQINKLNLCKSMIRAIDNLGMNDRFSLAQRVTYCYYVGRKAMFDGDFVAADKSLSFAFERCLGSASHNKRLILIYLIPVKMLLGIFPISSLLSKYNLNEFLGISEAVKSGDLRRMDSELNQHESFFLSCGVYLILEKLKLITYRNLFKRVCSIMKTHLLPIDVFTAALRLMGMDDIDQDETECILANLIYEGKIKGYLAHQQQKLVVSKLQPFPPLT 406
[Close]
BLAST of PCI domain-containing protein 2 vs. TrEMBL
Match: A0A0X3PHD1 (PCI domain-containing protein 2 OS=Schistocephalus solidus OX=70667 GN=PCID2 PE=4 SV=1)

HSP 1 Score: 389.037 bits (998), Expect = 3.987e-130
Identity = 183/347 (52.74%), Postives = 251/347 (72.33%), Query Frame = 1 
Query:  226 MGKQFVPWREMIVSHLNVLTHLNNKDLKGALEEQFNLIEIFSDLFEQIKDDNWFLPVMTVLTVDLRCLAHAMDYGIDSQVKHHSSAGENMKRVADCLMRLFRKCVSDSRSNVETSKKMGMMALCNQLFKIFFTISQLNLCKSLILAIENLGIIDKFSICQQVTYNYYVGRKCMFDDNFQKANESLTFAFENCHRDYVKNKRLILIYLIPVKMLLGNFPTDKLLVKYNLKEFSGVVKSVRIGDLCNLEAELNINGPFFISCGVYLILEKLKYIAYRNLFKTVSTMIGSHMISISAFSDALKFVGVSDIDIDETECILANLIFENKIKGYLAHQQQKLVMSKTNAFPSI 1266
            MG    PW E++ +HL  L  LN  D + A   Q  L++  + +F ++K++NW LPV+    VDLR  A A+D     + +  S+ G +M+RVA  +M+LF+ C +DSR+ +E SKK GMM L NQLFKI+F I++LNLCKS+I AIEN+ +   FS+ Q+VT+NYYVGRK MFD  F+ AN +LTFAFE C     +NKR++LIYLIPV+MLLG FP  KLL KYNL+EF G+ ++ + G++  L  +L     FFISCG++LILEKLK IAYRNLFK +++++ +H++ I+AF+DALKF+G+ D+D DET CIL+NLI++ KIKGYLAHQQQKLV+SK  AFP +
Sbjct:    1 MGIVLPPWDEIVSAHLRCLWALNKGDFEEACACQVILVKAIAKIFSEVKEENWMLPVVLTSAVDLRSFATALDTSTTGKAEPKSTYGGHMERVAQLIMKLFQICAADSRTAIEDSKKRGMMGLANQLFKIYFQINKLNLCKSIIRAIENMNMDPHFSLAQRVTFNYYVGRKAMFDGEFKLANTALTFAFERCLSSSERNKRMVLIYLIPVRMLLGIFPQQKLLGKYNLREFEGIAEAAKSGNIKRLNEDLGRYEDFFISCGIFLILEKLKVIAYRNLFKRIASILKTHLLPIAAFTDALKFMGMEDVDSDETSCILSNLIYDGKIKGYLAHQQQKLVVSKVQAFPPL 347
[Close]
BLAST of PCI domain-containing protein 2 vs. TrEMBL
Match: A0A5K3EQ90 (Uncharacterized protein OS=Mesocestoides corti OX=53468 PE=4 SV=1)

HSP 1 Score: 387.497 bits (994), Expect = 7.947e-129
Identity = 191/394 (48.48%), Postives = 268/394 (68.02%), Query Frame = 1 
Query:   88 TIETFISMVAKNVKALNGEELAKLFDLNDRHIQDPTLIPFIPEKMKMGKQF-VPWREMIVSHLNVLTHLNNKDLKGALEEQFNLIEIFSDLFEQIKDDNWFLPVMTVLTVDLRCLAHAMDYGIDSQVKHHSSAGENMKRVADCLMRLFRKCVSDSRSNVETSKKMGMMALCNQLFKIFFTISQLNLCKSLILAIENLGIIDKFSICQQVTYNYYVGRKCMFDDNFQKANESLTFAFENCHRDYVKNKRLILIYLIPVKMLLGNFPTDKLLVKYNLKEFSGVVKSVRIGDLCNLEAELNINGPFFISCGVYLILEKLKYIAYRNLFKTVSTMIGSHMISISAFSDALKFVGVSDIDIDETECILANLIFENKIKGYLAHQQQKLVMSKTNAFPSI 1266
            ++++++    + +   NG+ELA      D+H  +  L    PE + +G  F  PW E+  +HL  L  + + + + A   Q  L++  + +F ++K++NW LPV+ V+ VDLR  A+A+D     + + +S+ G +++R+A  +M+LF+ C +DSR+ +E SKK GMM L NQLFKI+F I++LNLCK +I AIEN+ +   FS+ Q++T+NYYVGRK MFD +F+ AN  LTFAFE C   +  NKRLILIYLIPV+MLLG FP + LL KY L+E  G+  + R G++  L  EL     FFISCG+YLILEKLK + YRNLFK V+ ++ +H+  I AF+D LK +GV DID DETECILANLI+E KIKGYLAHQQQKLV+SK  AFP +
Sbjct:    5 SVQSYLVEAHRLLSICNGKELATYLQCTDKHALNSRLALAEPETV-VGSVFEAPWDEIFSAHLRCLWAIASNNFEEACACQLVLVKALTKVFSEVKEENWMLPVVIVVAVDLRRFAYALDISNKRKDESNSTYGSHLERIAQAIMKLFQICAADSRTAIEDSKKRGMMGLANQLFKIYFQINKLNLCKPIIRAIENMNMDAYFSLAQRITFNYYVGRKAMFDGDFKMANTCLTFAFERCLASHHTNKRLILIYLIPVRMLLGIFPRNSLLQKYKLQELEGIANAARTGNVQKLGEELQRYEGFFISCGIYLILEKLKMLTYRNLFKKVAGLLKTHLQPIPAFTDILKVMGVEDIDTDETECILANLIYEGKIKGYLAHQQQKLVVSKVQAFPPL 397
[Close]
BLAST of PCI domain-containing protein 2 vs. TrEMBL
Match: A0A3P7BUP3 (PCI domain-containing protein OS=Schistocephalus solidus OX=70667 GN=SSLN_LOCUS151 PE=4 SV=1)

HSP 1 Score: 382.489 bits (981), Expect = 1.922e-127
Identity = 189/366 (51.64%), Postives = 252/366 (68.85%), Query Frame = 1 
Query:  169 NDRHIQDPTLIPFIPEKMKMGKQFVPWREMIVSHLNVLTHLNNKDLKGALEEQFNLIEIFSDLFEQIKDDNWFLPVMTVLTVDLRCLAHAMDYGIDSQVKHHSSAGENMKRVADCLMRLFRKCVSDSRSNVETSKKMGMMALCNQLFKIFFTISQLNLCKSLILAIENLGIIDKFSICQQVTYNYYVGRKCMFDDNFQKANESLTFAFENCHRDYVKNKRLILIYLIPVKMLLGNFPTDKLLVKYNLKEFSGVVKSVRIGDLCNLEAELNINGPFFISCGVYLILEKLKYIAYRNLFKTVSTMIGSHMISISAFSDALKFVGVSDIDIDETECILANLIFENKIKGYLAHQQQKLVMSKTNAFPSI 1266
            +DRH     L    PE   MG    PW E++ +HL  L  LN    KG  EE             Q+K++NW LPV+    VDLR  A A+D     + +  S+ G +M+RVA  +M+LF+ C +DSR+ +E SKK GMM L NQLFKI+F I++LNLCKS+I AIEN+ +   FS+ Q+VT+NYYVGRK MFD  F+ AN +LTFAFE C     +NKR++LIYLIPV+MLLG FP  KLL KYNL+EF G+ ++ + G++  L  +L     FFISCG++LILEKLK IAYRNLFK +++++ +H++ I+AF+DALKF+G+ D+D DET CIL+NLI++ KIKGYLAHQQQKLV+SK  AFP +
Sbjct:    4 SDRHALSAQLRVPEPENAVMGIVLPPWDEIVSAHLRCLWALN----KGDFEEACAC---------QVKEENWMLPVVLTSAVDLRSFATALDTSTTGKAEPKSTYGGHMERVAQLIMKLFQICAADSRTAIEDSKKRGMMGLANQLFKIYFQINKLNLCKSIIRAIENMNMDPHFSLAQRVTFNYYVGRKAMFDGEFKLANTALTFAFERCLSSSERNKRMVLIYLIPVRMLLGIFPQQKLLGKYNLREFEGIAEAAKSGNIKRLNEDLGRYEDFFISCGIFLILEKLKVIAYRNLFKRIASILKTHLLPIAAFTDALKFMGMEDVDSDETSCILSNLIYDGKIKGYLAHQQQKLVVSKVQAFPPL 356
[Close]
BLAST of PCI domain-containing protein 2 vs. Ensembl Cavefish
Match: pcid2 (PCI domain containing 2 [Source:NCBI gene;Acc:103047003])

HSP 1 Score: 333.183 bits (853), Expect = 7.480e-111
Identity = 176/396 (44.44%), Postives = 253/396 (63.89%), Query Frame = 1 
Query:   82 QMTIETFISMVAKNVKALNGEELAKLFDLNDRHIQDPTLIPFIPEKMKMGKQFVPWREMIVSHLNVLTHLNNKDLKGALEEQFNLIEIFSDLFEQIKDDNWFLPVMTVLTVDLRCLAHAMDYGIDSQVKHHSSAGENMKRVADCLMRLFRKCVSDSRSNVETSKKMGMMALCNQLFKIFFTISQLNLCKSLILAIENLGIIDKFSICQQVTYNYYVGRKCMFDDNFQKANESLTFAFENCHRDYVKNKRLILIYLIPVKMLLGNFPTDKLLVKYNLKEFSGVVKSVRIGDLCNLEAELNINGPFFISCGVYLILEKLKYIAYRNLFKTVSTMIGSHMISISAFSDALKFVGVSDIDIDETECILANLIFENKIKGYLAHQQQKLVMSKTNAFPSIS 1269
             +TI  ++  V + ++  +G    +L      H+ +P L    PE         P+ EM+ +HL     + N D   A + Q  +++ F   F+  K++NW LPVM  +T+DLR  A+  +  +  Q K     G+ +++ A+ LM  FR C SD+R+ ++ SKK GM+ L NQLFKI+F I++L+LCK LI AI++  + D +S+ Q+VTY YYVGRK MFD NF+ A E L+F+F++ HR   +NKRLILIYL+PVKMLLG+ PT++LL KY+L +F+ V K+V  G+L  L   L  +  FFI CG++LILEKLK I YRNLFK V  ++ +H + + AF  ALK +   D+DIDE +CILANLI+   IKGY++HQ QKLV+SK N FP +S
Sbjct:    3 HITINQYLQQVLEAIETRDGVFCGELLSFKHPHVANPRLQLSSPEDKCQQVLEPPYDEMVAAHLRCTYAVANHDFVEAYKCQTLVVQSFLKAFQAHKEENWALPVMFAVTLDLRIFANNAEQQL--QKKGKGKVGDMLEKAAEQLMSCFRVCASDNRAGIDDSKKWGMLFLINQLFKIYFKINKLHLCKPLIRAIDSSNLKDDYSMAQRVTYKYYVGRKAMFDSNFKLAEEYLSFSFQHSHRACQRNKRLILIYLLPVKMLLGHMPTNQLLRKYDLMQFADVTKAVSEGNLLLLNEALAKHETFFIRCGIFLILEKLKIITYRNLFKKVYLLLKTHQLPLDAFLVALKMMQCEDVDIDEVQCILANLIYMGHIKGYISHQHQKLVVSKQNPFPPLS 396
[Close]
BLAST of PCI domain-containing protein 2 vs. Ensembl Cavefish
Match: pcid2 (PCI domain containing 2 [Source:NCBI gene;Acc:103047003])

HSP 1 Score: 333.183 bits (853), Expect = 7.480e-111
Identity = 176/396 (44.44%), Postives = 253/396 (63.89%), Query Frame = 1 
Query:   82 QMTIETFISMVAKNVKALNGEELAKLFDLNDRHIQDPTLIPFIPEKMKMGKQFVPWREMIVSHLNVLTHLNNKDLKGALEEQFNLIEIFSDLFEQIKDDNWFLPVMTVLTVDLRCLAHAMDYGIDSQVKHHSSAGENMKRVADCLMRLFRKCVSDSRSNVETSKKMGMMALCNQLFKIFFTISQLNLCKSLILAIENLGIIDKFSICQQVTYNYYVGRKCMFDDNFQKANESLTFAFENCHRDYVKNKRLILIYLIPVKMLLGNFPTDKLLVKYNLKEFSGVVKSVRIGDLCNLEAELNINGPFFISCGVYLILEKLKYIAYRNLFKTVSTMIGSHMISISAFSDALKFVGVSDIDIDETECILANLIFENKIKGYLAHQQQKLVMSKTNAFPSIS 1269
             +TI  ++  V + ++  +G    +L      H+ +P L    PE         P+ EM+ +HL     + N D   A + Q  +++ F   F+  K++NW LPVM  +T+DLR  A+  +  +  Q K     G+ +++ A+ LM  FR C SD+R+ ++ SKK GM+ L NQLFKI+F I++L+LCK LI AI++  + D +S+ Q+VTY YYVGRK MFD NF+ A E L+F+F++ HR   +NKRLILIYL+PVKMLLG+ PT++LL KY+L +F+ V K+V  G+L  L   L  +  FFI CG++LILEKLK I YRNLFK V  ++ +H + + AF  ALK +   D+DIDE +CILANLI+   IKGY++HQ QKLV+SK N FP +S
Sbjct:    3 HITINQYLQQVLEAIETRDGVFCGELLSFKHPHVANPRLQLSSPEDKCQQVLEPPYDEMVAAHLRCTYAVANHDFVEAYKCQTLVVQSFLKAFQAHKEENWALPVMFAVTLDLRIFANNAEQQL--QKKGKGKVGDMLEKAAEQLMSCFRVCASDNRAGIDDSKKWGMLFLINQLFKIYFKINKLHLCKPLIRAIDSSNLKDDYSMAQRVTYKYYVGRKAMFDSNFKLAEEYLSFSFQHSHRACQRNKRLILIYLLPVKMLLGHMPTNQLLRKYDLMQFADVTKAVSEGNLLLLNEALAKHETFFIRCGIFLILEKLKIITYRNLFKKVYLLLKTHQLPLDAFLVALKMMQCEDVDIDEVQCILANLIYMGHIKGYISHQHQKLVVSKQNPFPPLS 396
[Close]
BLAST of PCI domain-containing protein 2 vs. Ensembl Sea Lamprey
Match: pcid2 (PCI domain containing 2 [Source:NCBI gene;Acc:492509])

HSP 1 Score: 322.783 bits (826), Expect = 1.707e-108
Identity = 158/327 (48.32%), Postives = 227/327 (69.42%), Query Frame = 1 
Query:  289 LNNKDLKGALEEQFNLIEIFSDLFEQIKDDNWFLPVMTVLTVDLRCLAHAMDYGIDSQVKHHSSAGENMKRVADCLMRLFRKCVSDSRSNVETSKKMGMMALCNQLFKIFFTISQLNLCKSLILAIENLGIIDKFSICQQVTYNYYVGRKCMFDDNFQKANESLTFAFENCHRDYVKNKRLILIYLIPVKMLLGNFPTDKLLVKYNLKEFSGVVKSVRIGDLCNLEAELNINGPFFISCGVYLILEKLKYIAYRNLFKTVSTMIGSHMISISAFSDALKFVGVSDIDIDETECILANLIFENKIKGYLAHQQQKLVMSKTNAFPSIS 1269
            + N +   A + Q  +++ F   F+  K++NW LP+M  +T+DLR  A++ D  +    K     G+ +++ AD LM  FR C SD+R+ ++ SKK GM+ L NQLFKI+F I++L+LCK LI AI++  + D+++  Q+VT+ YYVGRK MFD +F++A E L+FAF +CHR   KNKR+ILIYL+PVKMLLG+ PT +LL KY+L +F+ V K+V  G+L  L   L  +  FFI CG++LILEKLK I YRNL K V  ++ +H + + AF  AL+F+ V D+D+DE +CILANLI+   IKGY++HQ QKLV+SK N FP++S
Sbjct:    6 VGNHEYVEAYKYQTVVVQSFIKAFQADKEENWALPIMNSVTLDLRIFANSADLQLAR--KGRGKVGDTLEKAADTLMSCFRVCASDNRAGIDDSKKWGMLFLVNQLFKIYFKINKLHLCKPLIRAIDSSPLKDEYTKAQRVTFKYYVGRKAMFDSDFKQAEEYLSFAFSHCHRSSQKNKRMILIYLLPVKMLLGHMPTLRLLKKYDLMQFADVTKAVSEGNLLLLNEALTRHEAFFIRCGIFLILEKLKIITYRNLSKKVYQLLRTHQLPLDAFLVALRFMKVDDVDLDEVQCILANLIYNGHIKGYISHQHQKLVVSKQNPFPALS 330
[Close]
BLAST of PCI domain-containing protein 2 vs. Ensembl Sea Lamprey
Match: pcid2 (PCI domain containing 2 [Source:NCBI gene;Acc:492509])

HSP 1 Score: 209.149 bits (531), Expect = 1.085e-65
Identity = 100/218 (45.87%), Postives = 151/218 (69.27%), Query Frame = 1 
Query:  289 LNNKDLKGALEEQFNLIEIFSDLFEQIKDDNWFLPVMTVLTVDLRCLAHAMDYGIDSQVKHHSSAGENMKRVADCLMRLFRKCVSDSRSNVETSKKMGMMALCNQLFKIFFTISQLNLCKSLILAIENLGIIDKFSICQQVTYNYYVGRKCMFDDNFQKANESLTFAFENCHRDYVKNKRLILIYLIPVKMLLGNFPTDKLLVKYNLKEFSGVVKSVR 942
            + N +   A + Q  +++  S  F+  K++NW LP+M  +T+DLR  A+++       ++     G+ +++ AD LM  FR C SD+R+ ++ SKK GM+ L NQLFKI+F I++L+LCK LI AI++  + D+++  Q+VT+ YYVGRK MFD +F++A E L+FAF +CHR   KNKR+ILIYL+PVKMLLG+ PT +LL KY+L +F+ V K+VR
Sbjct:    6 VGNHEYVEAYKYQTVVVQYPSKAFQADKEENWALPIMNSVTLDLRIFANSVSLTFHPLLESIHKQGDTLEKAADTLMSCFRVCASDNRAGIDDSKKWGMLFLVNQLFKIYFKINKLHLCKPLIRAIDSSPLKDEYTKAQRVTFKYYVGRKAMFDSDFKQAEEYLSFAFSHCHRSSQKNKRMILIYLLPVKMLLGHMPTLRLLKKYDLMQFADVTKAVR 223
[Close]
BLAST of PCI domain-containing protein 2 vs. Ensembl Yeast
Match: THP1 (Nuclear pore-associated protein; component of TREX-2 complex (Sac3p-Thp1p-Sus1p-Cdc31p) involved in transcription elongation and mRNA export from the nucleus; involved in post-transcriptional tethering of active genes to the nuclear periphery and to non-nascent mRNP; contains a PAM domain implicated in protein-protein binding [Source:SGD;Acc:S000005433])

HSP 1 Score: 72.4034 bits (176), Expect = 3.510e-14
Identity = 71/294 (24.15%), Postives = 127/294 (43.20%), Query Frame = 1 
Query:  385 FLPVMTVLTVDLRCLAHAMDYGIDSQVKHHSSAGENMKRVADCLMRLFRKCVSDSRSNVETSKKMG----MMALCNQLFKIFFTISQLNLCKSLILAIEN---LGIIDKFSICQQVTYNYYVGRKCMFDDNFQKANESLTFAFEN------CHRDYVKNKRLILIYLIPVKMLLGNF----PTDKLLVKYNLKEFSGVVKSVRIGDLCNLEAELNINGPFFISCGVYLIL-EKLKYIAYRNLFKTV----STMIGSHMISISAFSDALKF-VGVSDIDIDETECILANLIFENK 1197
             +PV T  T  +  LA  +D      ++ H+ + + +  ++  L RLF   +   R N  ++   G    ++ L N+L  I+F I    LC ++    +    L   +++ + QQ+ Y Y +GR  + +     A      AF++       ++   +N   IL Y+IP  ++LG      P    L +  +  +S + K VR G++  +   L  N     +  + ++L EKL  + YRNL KTV    +T  G + +  S     L+  +G +  D    E  + N I   K
Sbjct:  109 LIPVATRETEFIINLAGKLD---SFHLQLHTRSHQFLSHISSILSRLF-NSIKPPRGNASSTNIPGKQRILLYLVNKLNNIYFRIESPQLCSNIFKNFQPKSMLAHFNEYQLDQQIEYRYLLGRYYLLNSQVHNAFVQFNEAFQSLLNLPLTNQAITRNGTRILNYMIPTGLILGKMVKWGPLRPFLSQETIDNWSVLYKHVRYGNIQGVSLWLRQNERHLCARQLLIVLLEKLPMVTYRNLIKTVIKSWTTEWGQNKLPYSLIERVLQLSIGPTFEDPGAQEITIYNGIHSPK 398
[Close]
BLAST of PCI domain-containing protein 2 vs. Ensembl Yeast
Match: YJR084W (Protein that forms a complex with Thp3p; may have a role in transcription elongation and/or mRNA splicing; identified as a COP9 signalosome component but phenotype and interactions suggest it may not be involved with the signalosome [Source:SGD;Acc:S000003844])

HSP 1 Score: 65.855 bits (159), Expect = 3.971e-12
Identity = 85/372 (22.85%), Postives = 155/372 (41.67%), Query Frame = 1 
Query:  304 LKGALEEQFNLIEIFSDLFEQI--KDDNWFLPVMTVLTVDLRCLAHAMDYGIDSQVKHHSSAGENMKRVADC---LMRLFRKCVSDSRSNVETSKKMGMMALCNQLFKIFFTISQLNLCKSLILAIE------NLGIIDKF----SICQQVTYNYYVGR--KCMFDDNFQKANESLTFAFENCHRDYVKNK---------RLILIYLIPVKMLLGNFPTDKLLVKYNLKEFSGV--------------VKSVRIGDLCNLEAELNINGPFFISCGVYLILEKLKYIAYRNLFK-------------TVSTMIGSHMISISAFSDALKFVGVSDIDIDETECILANLIFENKIKGYLAHQQQKLVMSKTNAFP 1260
            +K A EE   L      LF +I  ++ NW +  + V+   L  LA+              S+  N   + +C   + R F  C++D    +  +KK+G     N  F I+  +S  ++ K+L+  +E      ++  ++K        Q V YNYY+G+   C+ +D+ ++    L  A   C   YV++            I+I L+P+ +L     T +L   ++    +GV              V+SV  G+L   EA    +  FF+S G+++++  L+ + +  L +              +  ++ +     SA  D        +  +D  EC LA+ I    ++ YL+H  + +V SK   FP
Sbjct:   75 IKNATEELLRLANEQLKLFNRIVERETNWIIYPLWVMAKQLIRLAN-------------ESSELNKDSIEECGRTIHRSFTICLNDRNPRLNENKKIGCYMFANLEFSIYHRLSNKDMIKNLVKVLESRVNARDIPPLNKSLAMEHKSQVVLYNYYLGQYYGCLENDH-ERGFFHLNEALLQCPMLYVESTGKFVLQGQMEKIMILLVPLALL-----TKRLYPHWDHPVIAGVITRSKRLSQVYPTLVRSVISGNLSLYEATAASHERFFLSQGLHVVITLLREVVFTRLVQRCWQWGNDRKSIMPLKILLATKQHDSSANED-------EEEQLDALECRLASAIASGLLRAYLSHSNRCIVFSKKEPFP 420
[Close]
BLAST of PCI domain-containing protein 2 vs. Ensembl Nematostella
Match: EDO39944 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S8I2])

HSP 1 Score: 340.117 bits (871), Expect = 5.770e-114
Identity = 178/396 (44.95%), Postives = 251/396 (63.38%), Query Frame = 1 
Query:   88 TIETFISMVAKNVKALNGEELAKLFDLNDRHIQDPTLIPFIPEKMKMGKQFV--PWREMIVSHLNVLTHLNNKDLKGALEEQFNLIEIFSDLFEQIKDDNWFLPVMTVLTVDLRCLAHAMDYGIDSQVKHHSSAGENMKRVADCLMRLFRKCVSDSRSNVETSKKMGMMALCNQLFKIFFTISQLNLCKSLILAIENLGIIDKFSICQQVTYNYYVGRKCMFDDNFQKANESLTFAFENCHRDYVKNKRLILIYLIPVKMLLGNFPTDKLLVKYNLKEFSGVVKSVRIGDLCNLEAELNINGPFFISCGVYLILEKLKYIAYRNLFKTVSTMIGSHMISISAFSDALKFVGVSDIDIDETECILANLIFENKIKGYLAHQQQKLVMSKTNAFPSIS 1269
            T+  ++  V   + + NG+  A+L      HI  P L   IP+     +++   P  E++  HL  +  + N D   A   Q ++++ F  +F+  KD+NW LP+M+ +T+D+R  A   D  +    +     G+ +++ A+ +M  FR C SDSRS+++ SKK GM+AL   LFKI+F I++L+LCK LI AI++  I D+F +   V Y ++VGRK MFD +F  A E L+FAFE+CHR+  KNKR ILIYLIPVKMLLGNFP  ++L KY L +F  VVKSVR G+L   +  L     FFI CG+YLILEKLK I YRNLFK V  M+ +H + + AF  ALK + V D+DI E +CI+ANLI+   IKGY++HQ QKLV+SK NAFP ++
Sbjct:    5 TVIQYLQQVVDAMSSRNGDLAAELLSFTHPHIASPRLQ--IPDAQSQCERWFEPPLDELVACHLRAVWAVGNNDYVEAYNAQASVVQAFIKIFQAQKDENWSLPLMSAVTLDIRRFAVKADQQMCQ--RGAGKPGDTLEKAAEMIMGCFRVCASDSRSSLDVSKKWGMLALVVHLFKIYFKINKLHLCKPLIRAIDSAPIKDQFKLGHLVAYRFFVGRKYMFDGDFCSAEEYLSFAFEHCHRESPKNKRAILIYLIPVKMLLGNFPKQEVLKKYRLSQFIEVVKSVRQGNLLLFDETLERQQAFFIQCGIYLILEKLKIITYRNLFKKVYLMMKTHQLPLDAFVVALKAMKVDDMDIMEVQCIVANLIYMGYIKGYISHQHQKLVVSKQNAFPPLN 396
[Close]
BLAST of PCI domain-containing protein 2 vs. Ensembl Medaka
Match: pcid2 (PCI domain containing 2 [Source:NCBI gene;Acc:101155259])

HSP 1 Score: 302.753 bits (774), Expect = 4.045e-99
Identity = 174/400 (43.50%), Postives = 249/400 (62.25%), Query Frame = 1 
Query:   82 QMTIETFISMVAKNVKALNGEELAKLFDLNDRHIQDPTLIPFIPEKMKMGKQFVPWREMIVSHLNVLTHLNNKDLKGALEEQFNLIEIFSDLFEQIKDDNWFLPVMTVLTVDLRCLAHAMDYGIDSQVKHHSSAGENMKRVADCLMRLFRKCVSDSRSNVETSKKMGMMALCNQLFKIFF--TISQLNLCKSLILAIENLGIIDKFSICQQVTYNYYVGRKCMFDDNFQKANESLTFAFENCHRDYVKNKRLILIYLIPVKMLL--GNFPTDKLLVKYNLKEFSGVVKSVRIGDLCNLEAELNINGPFFISCGVYLILEKLKYIAYRNLFKTVSTMIGSHMISISAFSDALKFVGVSDIDIDETECILANLIFENKIKGYLAHQQQKLVMSKTNAFPSIS 1269
             +TI  ++  + + +    G   A+L      H+ +P L    PE         P+ EM+ +HL     + N D   A + Q  ++      F+  K++N  LP+M+ +T+DLR  A+  +  +  + K H   GE +++ A+ LM  FR C SD R+ ++ SKK GMM L NQLFKI+F   I++L+LCK LI AI++  + + +S  Q+VTY YYVGRK MFD +F+ A E L+FAF +CHR   KNKR+ILIYL+PVKMLL  G+ PT +LL KY+L +FS V K+V  G+L  L   L+ +  FFI CG++LILEKLK I YRNLFK    ++ +H + + AF  +LK + V D+D+DE +CILANLI+   IKGY++HQ QKLV+SK N FP +S
Sbjct:    3 HITINQYLQQIYEAIDNHEGSFCAELLSFKHPHVANPRLQLANPEDKCQQILEPPYDEMVAAHLCTYA-VANHDFVEAYKFQTLVVA-----FQSHKEENA-LPIMSAVTLDLRIFANNAEQQLQKKGKGHP--GEMLEKAAEQLMSCFRVCASD-RAGIDDSKKWGMMFLSNQLFKIYFKLQINKLHLCKPLIRAIDSSNLKNDYSQAQKVTYKYYVGRKAMFDSDFKPAEEFLSFAFHHCHRSSQKNKRMILIYLLPVKMLLFQGHMPTHQLLRKYDLMQFSDVTKAVE-GNLLLLNEALSKHETFFIRCGIFLILEKLKIITYRNLFKKY-LLLKTHQLPLDAFLVSLKMMQVEDVDLDEVQCILANLIYMGHIKGYISHQHQKLVVSKQNPFPPLS 390
[Close]
BLAST of PCI domain-containing protein 2 vs. Planmine SMEST
Match: SMESG000007339.1 (SMESG000007339.1)

HSP 1 Score: 601.282 bits (1549), Expect = 0.000e+0
Identity = 292/292 (100.00%), Postives = 292/292 (100.00%), Query Frame = 1 
Query:  397 MTVLTVDLRCLAHAMDYGIDSQVKHHSSAGENMKRVADCLMRLFRKCVSDSRSNVETSKKMGMMALCNQLFKIFFTISQLNLCKSLILAIENLGIIDKFSICQQVTYNYYVGRKCMFDDNFQKANESLTFAFENCHRDYVKNKRLILIYLIPVKMLLGNFPTDKLLVKYNLKEFSGVVKSVRIGDLCNLEAELNINGPFFISCGVYLILEKLKYIAYRNLFKTVSTMIGSHMISISAFSDALKFVGVSDIDIDETECILANLIFENKIKGYLAHQQQKLVMSKTNAFPSISQ 1272
            MTVLTVDLRCLAHAMDYGIDSQVKHHSSAGENMKRVADCLMRLFRKCVSDSRSNVETSKKMGMMALCNQLFKIFFTISQLNLCKSLILAIENLGIIDKFSICQQVTYNYYVGRKCMFDDNFQKANESLTFAFENCHRDYVKNKRLILIYLIPVKMLLGNFPTDKLLVKYNLKEFSGVVKSVRIGDLCNLEAELNINGPFFISCGVYLILEKLKYIAYRNLFKTVSTMIGSHMISISAFSDALKFVGVSDIDIDETECILANLIFENKIKGYLAHQQQKLVMSKTNAFPSISQ
Sbjct:    1 MTVLTVDLRCLAHAMDYGIDSQVKHHSSAGENMKRVADCLMRLFRKCVSDSRSNVETSKKMGMMALCNQLFKIFFTISQLNLCKSLILAIENLGIIDKFSICQQVTYNYYVGRKCMFDDNFQKANESLTFAFENCHRDYVKNKRLILIYLIPVKMLLGNFPTDKLLVKYNLKEFSGVVKSVRIGDLCNLEAELNINGPFFISCGVYLILEKLKYIAYRNLFKTVSTMIGSHMISISAFSDALKFVGVSDIDIDETECILANLIFENKIKGYLAHQQQKLVMSKTNAFPSISQ 292
[Close]
BLAST of PCI domain-containing protein 2 vs. Planmine SMEST
Match: SMESG000007206.1 (SMESG000007206.1)

HSP 1 Score: 431.409 bits (1108), Expect = 5.750e-150
Identity = 221/395 (55.95%), Postives = 280/395 (70.89%), Query Frame = 1 
Query:   85 MTIETFISMVAKNVKALNGEELAKLFDLNDRHIQDPTLIPFIPEKMKMGKQFVPWREMIVSHLNVLTHLNNKDLKGALEEQFNLIEIFSDLFEQIKDDNWFLPVMTVLTVDLRCLAHAMDYGIDSQVKHHSSAGENMKRVA-DCLMRLFRKCVSDSRSNVETSKKMGMMALCNQLFKIFFTISQLNLCKSLILAIENLGIIDKFSICQQVTYNYYVGRKCMFDDNFQKANESLTFAFENCHRDYVKNKRLILIYLIPVKMLLGNFPTDKLLVKYNLKEFSGVVKSVRIGDLCNLEAELNINGPFFISCGVYLILEKLKYIAYRNLFKTVSTMIGSHMISISAFSDALKFVGVSDIDIDETECILANLIFENKIKGYLAHQQQKLVMSKTNAFPSI 1266
            MTIE+ I+ + +N+++ NG ELAK + LND HIQD TLI F  E +KMG QF  W+EM+++HL ++ ++++K+ K                                  +DLR LA A++    S+VK  S    +   VA D + RLF +C  D  +  E+SK++GMMA+CNQLFKI+F I+Q  LCK LI AIENLGI +KFS+  QVT+NYYVGRK +FD+NFQKA E LTFAFENCHR+ VKNK+ IL+YLIPVKML+G    + LL+KYNL EF G++KSVR G++  L++ELN N  FFI+CG+YLILEKLKYIAYRNLFK V   + +H+I IS F DALKF GV DID+DET CILANLIFENKIKGYLAHQQQKLV+SKTNAFPS+
Sbjct:    1 MTIESLIANIVRNIRSQNGHELAKQYSLNDSHIQDQTLIGFHSEYVKMGSQFSLWKEMLIAHLKIINYVHDKNFK----------------------------------LDLRLLAFAVNSKTGSKVKDLSRDSRSSMTVAVDYIRRLFNECSFDKNTTFESSKRLGMMAMCNQLFKIYFAINQFTLCKPLINAIENLGIAEKFSVSHQVTFNYYVGRKYIFDNNFQKAVEYLTFAFENCHRNSVKNKKSILLYLIPVKMLMGILAPESLLMKYNLPEFVGIMKSVRNGNISFLDSELNKNKAFFINCGIYLILEKLKYIAYRNLFKNVCKAMENHLIPISVFCDALKFAGVPDIDMDETCCILANLIFENKIKGYLAHQQQKLVISKTNAFPSL 361
The following BLAST results are available for this feature:
BLAST of PCI domain-containing protein 2 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
PCID21.484e-11945.71PCI domain containing 2 [Source:HGNC Symbol;Acc:HG... [more]
PCID21.484e-11945.71PCI domain containing 2 [Source:HGNC Symbol;Acc:HG... [more]
PCID21.484e-11945.71PCI domain containing 2 [Source:HGNC Symbol;Acc:HG... [more]
PCID21.141e-11746.13PCI domain containing 2 [Source:HGNC Symbol;Acc:HG... [more]
PCID21.141e-11746.13PCI domain containing 2 [Source:HGNC Symbol;Acc:HG... [more]
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BLAST of PCI domain-containing protein 2 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 2
Match NameE-valueIdentityDescription
C27F2.103.550e-10544.01PCI domain-containing protein 2 homolog [Source:U... [more]
C27F2.103.550e-10544.01PCI domain-containing protein 2 homolog [Source:U... [more]
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BLAST of PCI domain-containing protein 2 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 1
Match NameE-valueIdentityDescription
PCID26.328e-10642.36gene:FBgn0036184 transcript:FBtr0076102[more]
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BLAST of PCI domain-containing protein 2 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 2
Match NameE-valueIdentityDescription
pcid21.175e-11143.69PCI domain containing 2 [Source:NCBI gene;Acc:4925... [more]
pcid21.175e-11143.69PCI domain containing 2 [Source:NCBI gene;Acc:4925... [more]
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BLAST of PCI domain-containing protein 2 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
rnf1381.076e-11544.95ring finger protein 138 [Source:Xenbase;Acc:XB-GEN... [more]
rnf1381.467e-10743.69ring finger protein 138 [Source:Xenbase;Acc:XB-GEN... [more]
rnf1388.720e-10644.30ring finger protein 138 [Source:Xenbase;Acc:XB-GEN... [more]
rnf1383.175e-10447.37ring finger protein 138 [Source:Xenbase;Acc:XB-GEN... [more]
rnf1382.865e-10142.42ring finger protein 138 [Source:Xenbase;Acc:XB-GEN... [more]
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BLAST of PCI domain-containing protein 2 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 2
Match NameE-valueIdentityDescription
Pcid21.291e-11746.21PCI domain containing 2 [Source:MGI Symbol;Acc:MGI... [more]
Pcid26.003e-1128.21PCI domain containing 2 [Source:MGI Symbol;Acc:MGI... [more]
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BLAST of PCI domain-containing protein 2 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q5JVF3|PCID2_HUMAN7.129e-11945.71PCI domain-containing protein 2 OS=Homo sapiens OX... [more]
sp|Q8BFV2|PCID2_MOUSE9.031e-11746.21PCI domain-containing protein 2 OS=Mus musculus OX... [more]
sp|Q5FWP8|PCID2_XENLA1.061e-11545.20PCI domain-containing protein 2 OS=Xenopus laevis ... [more]
sp|Q2TBN6|PCID2_BOVIN8.659e-11444.69PCI domain-containing protein 2 OS=Bos taurus OX=9... [more]
sp|Q5U3P0|PCID2_DANRE1.895e-11043.43PCI domain-containing protein 2 OS=Danio rerio OX=... [more]
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BLAST of PCI domain-containing protein 2 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A4S2MAW64.230e-13149.49PCI domain-containing protein OS=Opisthorchis feli... [more]
A0A504YG571.827e-13050.26PCI domain-containing protein 2 OS=Fasciola gigant... [more]
A0A0X3PHD13.987e-13052.74PCI domain-containing protein 2 OS=Schistocephalus... [more]
A0A5K3EQ907.947e-12948.48Uncharacterized protein OS=Mesocestoides corti OX=... [more]
A0A3P7BUP31.922e-12751.64PCI domain-containing protein OS=Schistocephalus s... [more]
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BLAST of PCI domain-containing protein 2 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 2
Match NameE-valueIdentityDescription
pcid27.480e-11144.44PCI domain containing 2 [Source:NCBI gene;Acc:1030... [more]
pcid27.480e-11144.44PCI domain containing 2 [Source:NCBI gene;Acc:1030... [more]
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BLAST of PCI domain-containing protein 2 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 2
Match NameE-valueIdentityDescription
pcid21.707e-10848.32PCI domain containing 2 [Source:NCBI gene;Acc:4925... [more]
pcid21.085e-6545.87PCI domain containing 2 [Source:NCBI gene;Acc:4925... [more]
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BLAST of PCI domain-containing protein 2 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 2
Match NameE-valueIdentityDescription
THP13.510e-1424.15Nuclear pore-associated protein; component of TREX... [more]
YJR084W3.971e-1222.85Protein that forms a complex with Thp3p; may have ... [more]
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BLAST of PCI domain-containing protein 2 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 1
Match NameE-valueIdentityDescription
EDO399445.770e-11444.95Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of PCI domain-containing protein 2 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 1
Match NameE-valueIdentityDescription
pcid24.045e-9943.50PCI domain containing 2 [Source:NCBI gene;Acc:1011... [more]
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BLAST of PCI domain-containing protein 2 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 2
Match NameE-valueIdentityDescription
SMESG000007339.10.000e+0100.00SMESG000007339.1[more]
SMESG000007206.15.750e-15055.95SMESG000007206.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30027678 ID=SMED30027678|Name=PCI domain-containing protein 2|organism=Schmidtea mediterranea sexual|type=transcript|length=1339bp
CAAAATGAAGACTATTAAATTTGTTTAAATTATTGAAATATTTGAATTTT
ATTTGAACAAATATTAATTTATCGAAAACCACAAATGACAATCGAAACAT
TCATATCAATGGTTGCTAAAAATGTGAAAGCATTAAATGGAGAAGAATTA
GCTAAACTATTTGATCTTAATGACCGGCATATACAAGATCCAACTTTAAT
ACCTTTTATACCTGAAAAAATGAAAATGGGTAAACAATTTGTTCCATGGA
GAGAAATGATAGTTAGCCATTTAAATGTTTTAACACATCTCAATAATAAG
GATTTAAAAGGTGCTTTAGAAGAGCAGTTTAATTTAATTGAGATATTTTC
TGACCTATTTGAACAAATAAAAGATGATAATTGGTTCCTACCAGTAATGA
CAGTATTAACTGTTGATCTGCGATGCTTAGCCCATGCTATGGATTATGGT
ATCGATTCTCAAGTGAAACATCACAGTAGTGCTGGAGAGAATATGAAAAG
AGTAGCTGATTGTTTAATGAGATTATTTCGCAAATGCGTTAGTGATAGCC
GTTCAAATGTGGAAACTTCGAAAAAAATGGGAATGATGGCACTTTGTAAT
CAATTGTTCAAAATATTTTTTACGATTAGCCAACTAAATCTCTGCAAATC
TCTTATTCTTGCCATAGAGAATCTTGGCATAATCGATAAATTTAGCATTT
GTCAACAAGTGACATACAATTATTATGTCGGTCGAAAATGCATGTTCGAT
GATAATTTCCAAAAAGCTAATGAGTCTTTAACTTTTGCTTTTGAAAATTG
TCATCGCGACTATGTTAAAAATAAGCGATTGATTTTGATTTATTTGATTC
CGGTTAAGATGTTGCTCGGTAATTTTCCGACTGATAAATTGCTTGTGAAA
TATAATCTGAAAGAATTTAGTGGTGTTGTTAAGAGTGTACGAATCGGGGA
TTTGTGTAATTTAGAAGCTGAATTGAACATCAATGGACCGTTTTTTATTA
GTTGTGGAGTGTATTTAATTCTTGAAAAACTGAAATATATTGCCTATCGC
AATCTCTTTAAAACTGTATCAACCATGATTGGTAGCCATATGATATCTAT
TTCGGCTTTTTCAGATGCTTTAAAATTCGTTGGCGTGTCGGATATTGATA
TCGATGAAACGGAATGCATTCTAGCCAATCTTATATTTGAGAATAAGATC
AAAGGCTATCTCGCTCATCAGCAACAAAAATTGGTAATGAGCAAAACAAA
TGCGTTTCCATCCATTAGCCAAACTACTGTAACTGTTACAAGATAAATCG
TGTTTGTAAAATAAATTGTTGTTTTTTGTGAAAAAAAAA
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protein sequence of SMED30027678-orf-1

>SMED30027678-orf-1 ID=SMED30027678-orf-1|Name=SMED30027678-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=404bp
MTIETFISMVAKNVKALNGEELAKLFDLNDRHIQDPTLIPFIPEKMKMGK
QFVPWREMIVSHLNVLTHLNNKDLKGALEEQFNLIEIFSDLFEQIKDDNW
FLPVMTVLTVDLRCLAHAMDYGIDSQVKHHSSAGENMKRVADCLMRLFRK
CVSDSRSNVETSKKMGMMALCNQLFKIFFTISQLNLCKSLILAIENLGII
DKFSICQQVTYNYYVGRKCMFDDNFQKANESLTFAFENCHRDYVKNKRLI
LIYLIPVKMLLGNFPTDKLLVKYNLKEFSGVVKSVRIGDLCNLEAELNIN
GPFFISCGVYLILEKLKYIAYRNLFKTVSTMIGSHMISISAFSDALKFVG
VSDIDIDETECILANLIFENKIKGYLAHQQQKLVMSKTNAFPSISQTTVT
VTR*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000101muscle cell
PLANA:0002109X1 cell
PLANA:0003001lateral region of the whole animal
Vocabulary: INTERPRO
TermDefinition
IPR036388WH-like_DNA-bd_sf
IPR000717PCI_dom
Vocabulary: molecular function
TermDefinition
GO:0005515protein binding
GO:0003690double-stranded DNA binding
GO:0003723RNA binding
Vocabulary: biological process
TermDefinition
GO:0000973posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery
GO:0006368transcription elongation from RNA polymerase II promoter
GO:0016973poly(A)+ mRNA export from nucleus
GO:0043066negative regulation of apoptotic process
GO:0043488regulation of mRNA stability
GO:0045579positive regulation of B cell differentiation
GO:0045893positive regulation of transcription, DNA-templated
GO:0048536spleen development
GO:0071033nuclear retention of pre-mRNA at the site of transcription
GO:0090267positive regulation of mitotic cell cycle spindle assembly checkpoint
GO:2000117negative regulation of cysteine-type endopeptidase activity
Vocabulary: cellular component
TermDefinition
GO:0005575cellular_component
GO:0070390transcription export complex 2
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR000717Proteasome component (PCI) domainPFAMPF01399PCIcoord: 277..387
e-value: 4.1E-15
score: 56.2
IPR000717Proteasome component (PCI) domainPROSITEPS50250PCIcoord: 209..390
score: 19.169
IPR036388Winged helix-like DNA-binding domain superfamilyGENE3DG3DSA:1.10.10.10coord: 327..398
e-value: 9.8E-29
score: 101.1
NoneNo IPR availableGENE3DG3DSA:1.25.40.570coord: 197..326
e-value: 2.0E-39
score: 136.4
NoneNo IPR availablePANTHERPTHR12732UNCHARACTERIZED PROTEASOME COMPONENT REGION PCI-CONTAININGcoord: 2..396
NoneNo IPR availablePANTHERPTHR12732:SF0PCI DOMAIN-CONTAINING PROTEIN 2coord: 2..396